The effect of trigeminal nerve and ganglion manipulation on recurrence of ocular herpes simplex in rabbits . - pubmed
Latent herpes simplex virus ( HSV ) has been demonstrated in the trigeminal ganglia of experimentally infected rabbits between episodes of spontaneous ocular recurrence . - pubmed
These studies provide additional evidence for the theory that the reservoir for latent ocular HSV in rabbits is the trigeminal ganglion . - pubmed
Moreover , the studies suggest that the transmission of latent HSV from the trigeminal ganglion to its infectious form in the peripheral tissues involves the trigeminal nerve . - pubmed
We have shown that mechanical and stereotaxic stimulation of the trigeminal ganglion is a reliable and rapid means of precipitating peripheral ocular shedding of HSV on command , a finding which should prove most productive in future research . - pubmed
[ Ultrastructural changes in the central nervous system of monkeys in poliomyelitis ] . - pubmed
The ultrastructure of cells of the central nervous system of Rhesus monkeys in experimental poliomyelitis caused by virus of poliomyelitis Type 3 was studied . - pubmed
Laminitis in the horse . - pubmed
To our knowledge , only one experimental study has mentioned morphological lesions similar to the hemolytic uremic syndrome in the human . - pubmed
Hepatitogenicity of three plaque purified mutant strains of mouse hepatitis virus , designated as MHV-2S , -2 M and -2L , isolated from MHV-2 infected SR - CDF1 - DBT cells was studied . - pubmed
Immunofluorescence revealed MHV specific antigen in the liver of MHV-2S infected mice in and around necrotic areas though less extensive than that of parental MHV-2 infected mice . - pubmed
With MHV-2 M specific fluorescence was restricted in degenerated hepatocytes in the small necrotic foci . - pubmed
In mice inoculated with MHV-2L only faint fluorescence was detected . - pubmed
Histopathologically , in the liver of MHV-2S infected mice zonal necrosis and cell infiltration were observed . - pubmed
There were spotty necrosis and focal cell infiltration in the liver of MHV-2 M infected mice and only small inflammatory foci were seen in MHV-2L infected mice . - pubmed
Thus , in rat cardiac myocytes a reduction in the myofilament Ca2 + response , possibly due to a decrease in myofilament Ca2 + sensitivity , is a mechanism for contractile depression due to clinically relevant ETOH concentrations. - pubmed
Some health care administrators have discussed the propriety the routine testing of faculty and students for HIV disease , especially when invasive procedures are involved : This article discusses some of the legal issues which attend routine HIV testing in this context . - pubmed
Mixed infection of the mosquitoes ' larvae of the first age group by densonucleasis virus and entomopathogenic strains of Pseudomonas fluorescens and Serratia marcescens enhanced viral infection in the presence of toxicosis induced by exogenic entomotoxic bacterial metabolites . - pubmed
Sixty - nine patients , mean age 50.0 years with an ischaemic cerebrovascular attack in the carotid circulation were subjected since 1983 to a complete examination incl . - pubmed
Recent studies have suggested that Plesiomonas shigelloides is a cause of diarrhea . - pubmed
shigelloides - infected patients had findings suggestive of colitis , and P. - pubmed
Continuous arteriovenous haemodialysis in critically ill patients . - pubmed
Continuous arteriovenous haemodialysis ( CAVHD ) is a new treatment for critically ill patients with renal failure that combines convective and diffusive solute removal . - pubmed
The clearance of urea ( 14.8 - 22.1 ml / min ) is sufficient to achieve a steady - state urea concentration of 22 mmol / l , even in patients with a high catabolic rate and cardiovascular instability . - pubmed
Initial experience in 36 critically ill patients with renal failure indicates that it is safe and reliable , with less associated morbidity than other techniques . - pubmed
Treatment of cryptococcal meningitis in mice with fluconazole . - pubmed
We compared fluconazole in murine cryptococcosis with ketoconazole and amphotericin B. - pubmed
Fluconazole was highly effective in suppressing cryptococcosis in mice challenged by the intravenous and intranasal routes , and was comparable with the other two drugs in its protective capacity . - pubmed
PMNs were collected from the rat pleural cavity after induction of one acute inflammatory reaction ( pleurisy induced by injection of a suspension of calcium pyrophosphate crystals ) . - pubmed
To determine the effect of lithium carbonate on the productivity and idiosyncrasy of written associations of euthymic outpatients with affective disorder , the authors assessed 22 patients at weekly intervals during lithium treatment , 2 consecutive weeks of placebo , and 2 consecutive weeks after lithium was resumed . - pubmed
Reproductive and endocrine gonadal functions in adults following multidrug chemotherapy for acute lymphoblastic or undifferentiated leukemia . - pubmed
The impact of aggressive chemotherapy on reproductive and endocrine gonadal function was studied in ten women and ten men with acute lymphoblastic leukemia ( ALL ) or acute undifferentiated leukemia ( AUL ) in complete remission . - pubmed
These results demonstrate that multidrug chemotherapy induced significant impairment of reproductive function in all male patients with early and complete recovery . - pubmed
Since the magnitude of such increases is thought to reflect the degree of lung injury , the results suggest that O3 exposure causes greater lung injury in older rats than in younger rats . - pubmed
The results of these studies further demonstrate that older rats are more susceptible to lung injury from O3 than younger rats . - pubmed
The effects of oxalate treatment on the smear layer of ground surfaces of human dentine . - pubmed
The role of oncogene expression in tumor metastasis was examined using the Abelson leukemia virus - transformed murine large cell lymphoma RAW117 . - pubmed
Histochemistry of synovium in experimental haemarthrosis in the rabbit . - pubmed
[ Clinical aspects and diagnosis of congenital dysfunction of the adrenal cortex ( salt - loosing form ) in young children ] . - pubmed
Induction of chromosomal aberrations and mutations with isomeric forms of L - threitol - I,4 - bismethanesulfonate in plant materials . - pubmed
The growth of Ehrlich 's ascites carcinoma in C3H mice and in mice of an unrelated closed colony . - pubmed
Hemodynamic and metabolic effects of physical training in four patients with essential hypertension . - pubmed
Stage - specific transforming genes of human and mouse B- and T - lymphocyte neoplasms . - pubmed
DNAs of 20 B - and T - lymphocyte neoplasms of human and mouse origin induced transformation of NIH / 3T3 cells with high efficiencies , indicating that these neoplasms contained activated transforming genes that were detectable by transfection . - pubmed
A case is reported of the reconstruction of a continent anus after an abdominoperineal resection for a patient who presented with a Dukes B adenocarcinoma at 4.5 cm from the anal verge . - pubmed
[ Effects of anisodamine on pulmonary circulation and function of the dog in shock ] . - pubmed
FH rats do not closely resemble CHS mice or human beings in having deficient NK activity and can not be considered the rat homolog of the CHS . - pubmed
Breathlessness was measured in 20 patients with severe chronic obstructive lung disease by the use of a visual - analogue scale . - pubmed
The value of short - term intermittent oxygen in patients with severe chronic obstructive lung disease needs to be evaluated in terms of both exercise ability and breathlessness . - pubmed
A 3.5 - year - old boy with eosinophilic cystitis was extensively investigated , but there was no evidence of parasitism . - pubmed
Pharmacodynamic interaction between hydralazine and phenobarbital in normotensive and spontaneously hypertensive rats . - pubmed
Primary indications include preoperative assessment of fluid and volume status , evaluation of patients with severe heart disease , and management of multisystem organ failure . - pubmed
For a neuropathological analysis of degenerative changes in saccadic disorders of patients , the histological identification of the burst neuron areas in man is important . - pubmed
Kinematic and dynamic axial computed tomography of the patello - femoral joint in patients with anterior knee pain . - pubmed
Thirty - eight knees of 26 patients with anterior knee pain ( 12 bilateral ) were included in the study . - pubmed
In 38 IDDM patients , there were four cases with microalbuminuria and one case with overt nephropathy . - pubmed
The measurements of UA in single - void specimens by ELISA is a satisfactory approach to detect impending nephropathy in IDDM patients . - pubmed
We determined the pharmacokinetics of 6 - methoxy-2 - naphythylacetic acid ( 6 - MNA ) , the active metabolite of nabumetone , in normal subjects and in subjects with impaired renal function , including subjects requiring hemodialysis . - pubmed
However , the increased half - life in patients with renal failure is offset by changes in the apparent volume of distribution that prevent the accumulation of 6 - MNA in the serum of patients with impaired renal function . - pubmed
Therefore dosage adjustments may not be necessary in patients with decreased renal function . - pubmed
A 43 year old man with inoperable aortic coarctation and severe hypertension requiring near maximal anti - hypertensive treatment was admitted in severe heart failure . - pubmed
The patient was re - admitted a week later with gross fluid retention and in renal failure . - pubmed
We propose that the renal haemodynamics in severe aortic coarctation are similar to those in bilateral severe renal artery stenosis and advise caution in the use of ACE inhibitors for adults with aortic coarctation . - pubmed
Strains of Bacteroides fragilis isolated from clinical specimens are known to be frequently resistant to penicillins or cephalosporins . - pubmed
Antiemetics in children receiving cancer chemotherapy . - pubmed
Side effects were found in 3 patients ( oliguria , 2 ; eruption due to drug , 1 ) and one case resulted in serious renal disorder . - pubmed
Thirty - two percent of hypothalamic neurons were stimulated by a hypercapnic stimulus in intact cats ; of those that were stimulated by hypercapnia , all had a basal discharge related to cardiovascular and/or respiratory activity . - pubmed
Hypoxia significantly increased the discharge rate of 21 % of hypothalamic units in intact animals ; 90 % of those had a cardiovascular and/or respiratory - related rhythm . - pubmed
PURPOSE : This study investigates the response rate to and toxicity of carboplatin and vincristine in children with recurrent low - grade gliomas ( LGGs ) or patients younger than 60 months with newly diagnosed LGGs . - pubmed
PATIENTS AND METHODS : Twenty - three children with recurrent and 37 children with newly diagnosed LGGs were treated with a 10 - week induction cycle of carboplatin and vincristine , followed by maintenance treatment with the same drugs . - pubmed
RESULTS : Twelve of 23 ( 52 % + /- 10 % ; 95 % confidence interval [ CI ] , 0.32 to 0.72 ) assessable children with recurrent disease had an objective response to treatment , which included a greater than 50 % reduction in tumor size in seven of 23 ( 30 % + /- 10 % ; 95 % CI , 0.10 to 0.50 ) . - pubmed
Twenty - three of 37 ( 62 % + /- .08 ; 95 % CI , 0.46 to 0.78 ) of newly diagnosed patients had an objective response , 16 of 37 ( 43 % + /- 0.08 % ; 95 % CI , 0.27 to 0.59 ) with greater than 50 % reduction in tumor size . - pubmed
The majority of those with an objective response had diencephalic tumors ( n = 29 ) , but children with thalamic ( n = 2 ) , cortical ( n = 1 ) , and brain stem ( n = 2 ) LGGs also responded to treatment . - pubmed
Hematologic toxicity was common , but resulted in cessation of therapy in only one patient . - pubmed
Six children have been removed from the study because of allergic reactions , which were considered to be carboplatin - associated . - pubmed
CONCLUSION : Carboplatin and vincristine have activity in children with recurrent and newly diagnosed progressive LGGs . - pubmed
This drug regimen is relatively well tolerated , and further studies are indicated to define the role of this combination of drugs in children with newly diagnosed LGGs . - pubmed
ONO-1078 antagonizes diarrhea - causing changes in ion transport and smooth muscle contraction induced by peptidoleukotrienes in rat and human colon in vitro . - pubmed
BACKGROUND : To diagnose baker 's asthma , occupational sensitization to wheat flour should be distinguished clearly from influences of cosensitization such as it may exist in pollinosis patients . - pubmed
Use of amiloride to reduce osmotic stress injury of mouse oocytes during cryopreservation . - pubmed
Our survey confirms that for treating physicians there remain uncertainties regarding the relative efficacy and tolerability of available antidepressant medications for patients with PD . - pubmed
METHODS AND RESULTS : A total of 14 617 women who reported hypertension and regular use of diuretics , beta - blockers , calcium channel blockers , ACE inhibitors , or a combination in 1988 were included in the analyses . - pubmed
Circular RNAs reminiscent of viroids and the human hepatitis delta virus have been proposed as possible nonconventional pathogens responsible for Crohn ' s disease and ulcerative colitis , two inflammatory bowel diseases . - pubmed
[ Immediate - acting oral morphine sulfate in patients with cancer pain ] . - pubmed
In this article , we describe our experience with oral morphine for the treatment of patients with cancer pain who were referred to a Palliative Care Unit . - pubmed
In 50 patients ( 96 % ) , there was a decreased intensity of pain from severe ( Visual Analogue Scale average ( VAS ) 8.7 ) to mild ( VAS average 1.9 ) . - pubmed
Even though most authors recommend morphine q4h , in our population q6h was enough to achieve pain control in 83 % of patients . - pubmed
It should be known by the medical population that morphine is essential therapy for pain in cancer patients . - pubmed
This study confirms that morphine is an excellent drug for the control of pain in cancer patients , with minimal dosages and controllable side effects . - pubmed
We present a case of a radically resected duodenal stromal tumour with benign features , in a young woman , with metastases to the liver and peritoneum occurring 8 years after the initial diagnosis . - pubmed
BACKGROUND : Induction chemotherapy has become the standard of care for patients with locally advanced breast cancer ( LABC ) and currently is being evaluated in prospective clinical trials in patients with earlier - stage disease . - pubmed
To better gauge the role of axillary lymph node dissection in patients with LABC this study was performed to assess initial axillary status on physical and ultrasound examination , axillary tumor downstaging following induction chemotherapy , and the accuracy of physical examination compared with axillary sonography in predicting which patients will have axillary lymph node metastases found on pathologic examination . - pubmed
METHODS : Between 1992 and 1996 , 147 consecutive patients with LABC were registered in a prospective trial of induction chemotherapy using 5 - fluorouracil , doxorubicin , and cyclophosphamide . - pubmed
RESULTS : Following induction chemotherapy , 43 ( 32 % ) of the 133 patients with clinically positive lymph nodes on initial examination had axillary tumor downstaging as assessed by physical and ultrasound examination . - pubmed
Among the 55 patients in whom the findings of both physical and ultrasound examination of the axilla were negative following induction chemotherapy , 29 patients ( 53 % ) were found to have axillary lymph node metastases on pathologic examination of the axillary contents . - pubmed
However , 28 ( 97 % ) of these patients had either 1 to 3 positive lymph nodes or only micrometastases 2 to 5 mm in diameter . - pubmed
CONCLUSIONS : Preoperative clinical assessment of the axilla by physical examination combined with ultrasound examination is not completely accurate in predicting metastases in patients with LABC following tumor downstaging . - pubmed
However , patients with negative findings on both physical and ultrasound examinations of the axilla may be potential candidates for omission of axillary dissection if the axilla will be irradiated because minimal axillary disease remains . - pubmed
Gold - thioglucose - induced hypothalamic lesions inhibit metabolic modulation of light - induced circadian phase shifts in mice . - pubmed
2 - deoxy - D - glucose and in hypoglycemic mice fasted for 30 h , pre - treated with 5 IU / kg s.c . - pubmed
In contrast , similar metabolic challenges in mice with gold - thioglucose - induced hypothalamic lesions did not significantly affect light - induced phase delays compared to mice treated with gold - thioglucose and fed ad libitum . - pubmed
This concept has engaged scientists to investigate human models to explore the molecular basis of hypertrophy or dilation of the myocardium . - pubmed
Helicobacter pylori infection in postoperative patients with biliary atresia . - pubmed
The prevalence of Helicobacter pylori infection in postoperative patients with biliary atresia ( BA ) was investigated in relation to esophageal varices , portal - hypertensive gastropathy ( PHG ) , and peptic ulcer disease ( PUD ) in 25 Japanese patients ( 10 boys and 15 girls ) aged from 16 months to 20 years . - pubmed
Esophageal varices were found in 19 patients ( 60 % of group A and all patients in groups B and C ) and PHG in 3 group B patients . - pubmed
pylori infection and PUD in postoperative patients with BA was quite low , and a pathological relationship with the severity of liver disease could not be determined in these patients . - pubmed
The Centers for Disease Control and Prevention HIV classifications for the 18 HIV - infected children were : A ( n = 7 ) , B ( n = 6 ) , and C ( n = 5 ) . - pubmed
By parent report , 7 HIV - infected children napped and 2 noninfected children napped , indicating greater daytime fatigue in the HIV - infected children . - pubmed
HIV - infected children also reported a greater level of evening tiredness ( 2.47 vs 1.8 ) . - pubmed
Some new approaches are described for patients with hormone - refractory prostate cancer . - pubmed
CONCLUSIONS : Newer tumor - biology - based combinations are promising in the treatment of hormone - refractory prostate cancer , but their effect on patient survival needs to be evaluated in larger clinical trials . - pubmed
Seasonal consumption of salad vegetables and fresh fruit in relation to the development of cardiovascular disease and cancer . - pubmed
OBJECTIVE : To investigate the protective association between seasonality of consumption of fresh fruit or salad vegetables and cancer and cardiovascular disease ( CVD ) development . - pubmed
CONCLUSIONS : Diets high in fresh fruit and salad vegetables appear protective against cancer and CVD . - pubmed
The effects of chloroquine on bleeding time and disappearance of platelet 5 - hydroxytryptamine in rabbits . - pubmed
Bleeding times in chloroquine - treated and control rabbits were not significantly different ( 64.8 + /- 2.2 vs. 62.3 + /- 4.0 sec , respectively ) . - pubmed
CONCLUSION : Chloroquine prolongs platelet survival but does not affect bleeding time in rabbits . - pubmed
Short term effect of continuous positive airway pressure on muscle sympathetic nerve activity in patients with chronic heart failure . - pubmed
OBJECTIVE : To test the hypothesis that the short term application of continuous positive airways pressure ( CPAP ) increases muscle sympathetic nerve activity in patients with congestive heart failure . - pubmed
PATIENTS : 10 patients with congestive heart failure ( New York Heart Association functional class III ; mean ( SEM ) left ventricular ejection fraction 22 ( 1)% ) and 10 healthy subjects matched for age , sex , and weight . - pubmed
Development of a reliable approach for prediction of environmental disease not only will provide fundamental information regarding the genetic basis of human disease but will be useful for reducing disease burden in the population and for advancing patient care . - pubmed
Depressive symptoms and risk of functional decline and death in patients with heart failure . - pubmed
OBJECTIVES : We sought to examine whether depressive symptoms are associated with poorer prognosis in patients with heart failure . - pubmed
BACKGROUND : Depression is an established risk factor for poor outcome in patients with coronary heart disease ( CHD ) . - pubmed
Little is known of its role in patients with heart failure . - pubmed
METHODS : We prospectively followed 391 patients & gt ; or = 50 years of age who met criteria for decompensated heart failure on hospital admission . - pubmed
CONCLUSIONS : An increasing number of depressive symptoms is a negative prognostic factor for patients with heart failure , just as it is for patients with CHD . - pubmed
A case of acute myocardial infarction associated with a mild blunt thoracic trauma in a 60 - year - old woman with normal coronary angiography is described . - pubmed
METHOD AND DESIGN : Retrospective cohort study of 20,222 children aged 1 month to 18 years , receiving Medicaid , who had a first diagnosis of gastroenteritis , diarrhea , or vomiting between January 1 , 1998 , and December 31 , 1998 . - pubmed
[ Study of the causes of recurrence of patients with glottic cancer after partial laryngectomy ] . - pubmed
OBJECTIVE : To study the causes of recurrence of patients with glottic cancer after partial laryngectomy and to propose some possible measures for the prevention of glottic cancer postoperative recurrence . - pubmed
METHOD : A retrospective review of consecutive 46 patients with recurrent glottic cancer after partial laryngectomy was conducted . - pubmed
RESULT : Among 46 patients diagnosed with glottic cancer recurrence after partial laryngectomy , 32 cases were local recurrences and 14 were regional metastasis or local - regional recurrences . - pubmed
Artificial caries lesions were produced on coronal dentin of extracted human molars . - pubmed
Analysis in human fetuses and patients with cryptorchidism . - pubmed
We studied the distal insertions of the gubernaculum in human fetuses and patients with cryptorchidism . - pubmed
MATERIALS AND METHODS : We studied 326 gubernacula in 163 human fetuses at 10 to 35 weeks of gestation and 133 gubernacula in 101 patients with cryptorchidism ( mean age 6.4 years ) . - pubmed
CONCLUSIONS : The existence of anomalous insertions at the distal portion of the gubernaculum is rare in human fetuses and patients with cryptorchidism . - pubmed
We found in murine allogeneic bone marrow transplantation ( BMT ) models that recipients of alpha(4)beta(7)(- ) donor T cells had significantly less graft - versus - host disease ( GVHD ) morbidity and mortality compared with recipients of alpha(4)beta(7)(+ ) donor T cells . - pubmed
Effects of thienopyridines ticlopidine and clopidogrel on acute changes of these parameters in patients with NSTEACS are not well investigated . - pubmed
METHODS : Patients with NSTEACS , treated with aspirin and unfractionated heparin ( n=37 , & lt;48 hours from pain onset , Braunwald class IIIb ) were randomized to open ticlopidine ( n=19 , 500 mg BID loading dose for 2 days and 250 mg BID for subsequent 5 days ) or no ticlopidine ( n=18 ) . - pubmed
Esophagitis impairs esophageal smooth muscle reactivity in the rat model : an in vitro study . - pubmed
All test animals apart from the controls developed gross and histologic evidence of esophagitis . - pubmed
These changes may correspond to the functional motor abnormalities of the esophagus seen in patients with reflux esophagitis . - pubmed
We retrospectively identified all of the pediatric patients with Noonan syndrome seen at our institution and reviewed the ocular findings to determine specific ocular manifestations in pediatric Noonan syndrome patients . - pubmed
The muscle of the obese Zucker rat is highly insulin resistant . - pubmed
The purpose of this review is to discuss the cellular defects associated with the muscle insulin resistance of the obese Zucker rat , as well as the mechanisms by which exercise training alleviates or compensates for these defects . - pubmed
BACKGROUND : In the 2003 West Nile virus ( WNV ) epidemic , Colorado reported more WNV cases than any other state , including an unprecedented number in organ transplant recipients . - pubmed
All but 1 patient had a prodrome typical of WNV encephalitis in nonimmunosuppressed patients . - pubmed
Ten patients developed meningoencephalitis , which in 3 cases was associated with acute flaccid paralysis . - pubmed
One patient developed acute flaccid paralysis without encephalitis . - pubmed
Six patients had significant movement disorders including tremor , myoclonus , or parkinsonism . - pubmed
Magnetic resonance images of the brain were abnormal in 7 of 8 tested patients , and electroencephalograms were abnormal in 7 of 7 , with 2 showing periodic lateralized epileptiform discharges . - pubmed
Nine of 11 patients survived infection , but 3 had significant residual deficits . - pubmed
One patient died 17 days after admission , and autopsy findings revealed severe panencephalitic changes with multifocal areas of necrosis in the cerebral deep gray nuclei , brainstem , and spinal cord as well as diffuse macrophage influx in the periventricular white matter . - pubmed
A second patient died of complications of WNV encephalitis 6 months after hospital admission . - pubmed
Zinc nutritional status and its relationships with hyperinsulinemia in obese children and adolescents . - pubmed
A study was carried out in a group of obese children and adolescents ( n=23 ) and compared to a control group ( n=21 ) , both between 7 and 14 yr of age . - pubmed
As a result , considering that zinc is part of the synthesis and secretion of this hormone , an assessment is necessary of the possible participation of the oligoelement in the mechanisms of insulin resistance , commonly present in obese patients . - pubmed
Antigen - based therapies using ignored determinants of beta cell antigens can more effectively inhibit late - stage autoimmune disease in diabetes - prone mice . - pubmed
Using a panel of immunogenic peptides from various beta cell Ags , we evaluated the factors influencing the efficacy of Ag - based therapies in diabetes - prone NOD mice with advanced disease . - pubmed
CONTEXT : A 1990 National Institutes of Health Consensus Conference recommended that patients with stage III colon cancer receive adjuvant chemotherapy because survival was improved in clinical trials in patients who received a 5 - fluorouracil - based regimen . - pubmed
CONCLUSIONS : Adjuvant chemotherapy use has increased from 1990 to 2002 for patients with stage III colon cancer with an associated increase in 5 - year survival of 16 % . - pubmed
New options for adjuvant therapy in 2004 - 2005 may further improve the outcome of patients with stage III colon cancer . - pubmed
In the patients with diffusely severe VAS ( & gt;70 % lumen reduction , the length of plaque & gt;1 cm or multiple plaques ) or localized critical VAS ( & gt;90 % lumen reduction ) diagnosed by TCDFI and confirmed with DSA , a narrowed and tortuous VA was demonstrated with minimal flow on color Doppler imaging and decreased 50 % of normal PSV and PSV & lt;0.30 m / s accompanied by slow early systolic acceleration on Doppler spectrum . - pubmed
[ Hemangiosarcoma in a dog ] . - pubmed
Furthermore , it may be worth using FG in the observation of substituted eye movements in patients with horizontal gaze palsy due to a pontine tegmental injury . - pubmed
The study comprised 62 men with ED : 16 neurogenic ( NGED ) , 15 arteriogenic ( AGED ) , 11 venogenic ( VGED ) and 22 psychogenic ( PGED ) . - pubmed
OBJECTIVE : To compare the hemodynamic state , the severity and reversibility of pulmonary arterial hypertension ( PAH ) in patients with Down ' s syndrome and congenital heart disease ( CHD ) with respect to those without chromosomal pathologies . - pubmed
MATERIAL AND METHODS : 30 patients with congenital heart disease and left to right shunt were studied , corroborated by echocardiography ; 16 patients had Down ' s syndrome and CHD and the control group was constituted by 14 patients without chromosomal abnormalities and with CHD . - pubmed
CONCLUSIONS : Although patients with Down ' s syndrome present CHD with greater predisposition to develop irreversible pulmonary arterial hypertension like common atrioventricular canal , the hemodynamic behavior of pulmonary hypertension and during the challenge with oxygen was similar in both groups . - pubmed
Endovascular treatment of complicated aortic aneurysms in patients with underlying arteriopathies . - pubmed
Patients with arteriopathies including giant cell arteritis , Marfan syndrome , and Takayasu ' s disease are at risk for aneurysmal degeneration of the aorta . - pubmed
The purpose of this study was to examine outcomes following endovascular stent graft ( EVSG ) repair of aortic aneurysms in this patient population . - pubmed
Over an 8 - year period , 11 patients ( six men , five women ) with arteriopathies underwent endovascular aortic repair . - pubmed
EVSG repair of aortic aneurysms is feasible and can be safely performed in patients with arteriopathies . - pubmed
Long - term durability in this younger group of patients who carry an ongoing risk of arterial degeneration remains to be determined . - pubmed
CASE REPORT : A 67 - year - old female was referred for treatment of chest wall pain following a T-12 compression fracture . - pubmed
The patient experienced a rapid and complete loss of sensation and movement below the T-10 level within five minutes after the injection . - pubmed
PATIENTS AND METHODS : We conducted a retrospective review of patients with pulmonary metastases ( PM ) from HCC who had undergone curative PM - ectomy at National Taiwan University Hospital between 1990 and 2004 . - pubmed
CONCLUSION : Patients with longer DFIs and fewer PMs can benefit from PM - ectomy in HCC . - pubmed
( 1 ) For patients with hypercholesterolaemia requiring primary or secondary prevention , pravastatin , simvastatin and atorvastatin have a proven benefit in terms of mortality and/or morbidity . - pubmed
Hepatotoxic effects occur in about 2 % of patients , especially in those using high daily doses or sustained - release formulations . - pubmed
Vestibular rehabilitation in a patient with whiplash - associated disorders . - pubmed
In this paper , the comprehensive treatment of a patient with whiplash - associated disorders is presented . - pubmed
A 71 - year - old woman was admitted to our hospital due to unilateral leg edema . - pubmed
In patients with well - defined syndrome of chronic mesenteric and gastric ischemia or with exercise - induced pain , good results can be expected with division of the median arcuate ligament with open celiac artery reconstruction . - pubmed
Laparoscopic division of the median arcuate ligament followed by celiac artery stenting is an effective , minimally invasive technique to manage selected patients with celiac artery compression syndrome . - pubmed
A fast , geometric beam angle optimization ( BAO ) algorithm for clinical intensity - modulated radiation therapy ( IMRT ) was implemented on ten localized prostate cancer patients on the Radiation Therapy Oncology Group ( RTOG ) 0126 protocol . - pubmed
Dialysis therapy has the same rules for diabetic and non - diabetic patients . - pubmed
Tolerance to ultrafiltration is lower and haemodynamic instability is easier to provoke in diabetics than in non - diabetic patients . - pubmed
Customized , specifically designed and targeted intervention in diabetic patients may slow down the progression of diabetic vascular changes , improve diabetes compensation and the patients ' quality of life . - pubmed
A water deprivation test was developed for the differentiation of polyuric disorders in birds using the racing pigeon as a model . - pubmed
For a period of 3 days of food and water deprivation , urine and plasma osmolalities and body weight of 40 clinically healthy racing pigeons were monitored . - pubmed
Muscle action potentials in human poliomyelitis before and after treatment by Billig 's method . - pubmed
We describe here one such young male patient with unilateral lacrimal gland swelling . - pubmed
Patient is well and has no other manifestation or recurrence of the disease during a follow - up of 24 months . - pubmed
Abnormal fMRI Connectivity in Children with Dyslexia During a Phoneme Task : Before But Not After Treatment . - pubmed
Brains of 18 children with dyslexia ( 5 girls , 13 boys ) and 21 and without dyslexia ( 8 girls , 13 boys ) were scanned before and after the children with dyslexia received instructional treatment . - pubmed
Children with dyslexia had greater functional connectivity from the left inferior frontal gyrus seed point to the right inferior frontal gyrus than did the children without dyslexia . - pubmed
Compared to adults with and without dyslexia who differed in bilateral connectivity from left inferior frontal gyrus on the same task , the children with and without dyslexia differed in left side connectivity from left inferior frontal gyrus . - pubmed
At Time 2 after treatment , the children with dyslexia , who had participated in a three - week instructional program that provided explicit instruction in linguistic awareness , alphabetic principle ( taught in a way to maximize temporal contiguity of grapheme - phoneme associations ) , decoding and spelling , and a writers ' workshop , did not differ from the children without dyslexia in any of the clusters in the group difference map identifying differences between dyslexics and good readers , showing that functional connectivity ( and not just regions of interest ) may normalize following instructional treatment . - pubmed
Effect of oral erythromycin therapy in patients with aseptic loosening of joint prostheses . - pubmed
We recruited 32 AL patients . - pubmed
AL patients were treated with either EM ( 600 mg / day , n=18 ) or placebo ( n=14 ) daily , started one month before surgery and ending on the day of surgery . - pubmed
Our results suggest that EM represents a biological cure or prevention for those patients who might need repeated revision surgeries and/or show the early signs of progressive osteolysis after TJR . - pubmed
Possible modulating action of plant infusion of Ocimum sanctum L. on chromosomal aberrations and sister chromatid exchanges induced by chlormadinone acetate in human lymphocytes in vitro . - pubmed
The aim of the present study is to study the anti- genotoxic activity of the plant infusion against the CMA induced genotoxic damage on cultured human lymphocytes , using chromosomal aberrations and sister chromatid exchanges ( SCFs ) as parameters . - pubmed
The results of the present study suggest that the plant infusion per se does not have genotoxic potential , but can modulate the genotoxicity of chlormadinone acetate in human lymphocytes in vitro . - pubmed
Diary and patient - reported outcomes in patients with severe overactive bladder switching from tolterodine extended release 4 mg / day to solifenacin treatment : An open - label , flexible - dosing , multicentre study . - pubmed
METHODS : VERSUS was a 12 - week , open - label , flexible - dosing study assessing the efficacy , tolerability and effects on health - related quality of life ( HRQOL ) of solifenacin in patients with OAB . - pubmed
The PPBC scale and Overactive Bladder Questionnaire ( OAB - q ) assessed patient - reported outcomes . - pubmed
CONCLUSION : In patients with severe OAB symptoms , solifenacin was effective and well tolerated . - pubmed
Solifenacin improved urgency , incontinence , micturition frequency , nocturia and nocturnal voids in patients continuing to experience urgency episodes on tolterodine ER 4 mg / day . - pubmed
Patients experienced improvements in HRQOL and perceived bother from OAB . - pubmed
We performed a single - institution phase II study to evaluate the efficacy and toxicities of vinorelbine monotherapy in patients previously treated with anthracyclines and taxanes . - pubmed
Grade 3 or 4 hematologic toxicities included neutropenia in 18 patients ( 69.2 % ) and anemia in four patients ( 15.3 % ) . - pubmed
Grade 1 or 2 peripheral neuropathy was observed in 11 patients ( 42.3 % ) , however there were no cases of grade 3 or 4 peripheral neuropathy . - pubmed
The results of this study indicate that vinorelbine monotherapy was feasible regimen with manageable toxicities in patients with metastatic breast cancer who were previously exposed to anthracyclines and taxanes . - pubmed
The severity of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis is related to altered cerebrospinal fluid dynamics . - pubmed
The aim of this study was to investigate the relationship between a Doppler cerebral venous hemodynamic insufficiency severity score ( VHISS ) and cerebrospinal fluid ( CSF ) flow dynamics in 16 patients presenting with CCSVI and relapsing - remitting MS ( CCSVI - MS ) and in eight healthy controls ( HCs ) . - pubmed
This study demonstrates that venous outflow disturbances in the form of CCSVI significantly impact on CSF pathophysiology in patients with MS . - pubmed
albicans cells , with obvious differences between cells recovered from culture and those from a murine model of disseminated candidiasis . - pubmed
Oral phosphate binders in patients with kidney failure . - pubmed
HIV drug resistance testing is recommended as routine part of clinical practice in HIV / AIDS treatment and care . - pubmed
Postural control of mouth breathing school aged children regarding gender . - pubmed
BACKGROUND : Postural control of mouth breathing school aged children . - pubmed
Our data suggest that intermediate - risk ERMS is driven by a common set of genomic defects , a finding that has important implications for the application of targeted therapies to improve the treatment of children diagnosed with this disease . - pubmed
The effect of metoprolol alone and combined metoprolol - felodipin on the digital microcirculation of patients with primary Raynaud ' s syndrome . - pubmed
METHODS : We enrolled in this study 46 patients suffering from both hypertension and primary Raynaud ' s syndrome . - pubmed
PARTICIPANTS : Caregivers of children with motor disabilities completed an interview survey for children 0 - 21 years . - pubmed
Efficacy and safety of entecavir in clinical practice in treatment - naive Caucasian chronic hepatitis B patients . - pubmed
METHODS : We retrospectively analysed data from 190 nucleos(t)ide - naive chronic hepatitis B patients treated with entecavir ( 0.5 mg / day ) in 25 Spanish centres . - pubmed
Thirty - four per cent of the patients who underwent biopsy had advanced fibrosis / cirrhosis . - pubmed
METHODS : Retrospective case series was taken to study the clinical data of 15 patients ( 30 eyes ) diagnosed with Takayasu ' s arteritis at Peking Union Medical College Hospital from 1992 to 2010 . - pubmed
Two patients recognized by initial presentation of impaired vision prior to the diagnosis of Takayasu ' s arteritis . - pubmed
Six cases were classified as brachiocephalic arteritis , and 9 patients belonged to extensive arteritis . - pubmed
The first symptom in some patients can be impaired vision . - pubmed
BACKGROUND : Mycoplasma pneumoniae ( Mp ) frequently colonizes the airways of patients with chronic asthma and likely contributes to asthma exacerbations . - pubmed
CONCLUSION : The therapy of TRAE combined with cryoablation contributes to reduce the percentage of Treg cells and improve the immune situation of patients with renal cell carcinoma , which consequently increase tumor necrosis rate and prolong the patients ' survival duration . - pubmed
PGI ( 2 ) analogs have been used effectively in primary pulmonary hypertension in adults and have shown promise in PPHN . - pubmed
Study of treatment using percutaneous acetabuloplasty and interstitial implantation of ( 125 ) I seeds for patients with metastatic periacetabular tumors . - pubmed
METHODS : A retrospective analysis was performed on 24 patients with metastatic periacetabular tumors who underwent combined therapy of percutaneous acetabuloplasty and interstitial implantation of ( 125 ) I seeds between February 2003 and June 2011 . - pubmed
Complete pain relief was achieved in 58 % ( 14 of 24 ) of patients , and pain reduction was achieved in the 42 % remaining ( 10 ) patients . - pubmed
Pain recurred in one patient 3 months after surgery . - pubmed
Comparing the KPS , Harris and VAS scores pre- and postoperativelyat 1 , 6 , and 12 months , the combined therapy method was significantly effective in metastatic periacetabular tumor patients ( P<0.05 ) . - pubmed
CONCLUSIONS : Percutaneous cementoplasty with interstitial implantation of ( 125 ) I seeds is an effective treatment method for metastatic periacetabular tumor patients , providing tumor resistance , pain relief , increased bone stability , and improved quality of life for patients . - pubmed
We present a case of acute oxalate nephropathy in a patient with underlying systemic lupus erythematosus who recently received intravenous vitamin C. - pubmed
Clinical and polysomnographic features of patients with multiple system atrophy in Southwest China . - pubmed
PURPOSE : The association between clinical features and polysomnographic variables of Chinese patients with multiple - system atrophy ( MSA ) remains largely unknown . - pubmed
METHODS : This study assessed 30 patients with MSA from Southwest China using the Unified Multiple - System Atrophy Rating Scale ( UMSARS ) . - pubmed
RESULTS : Of the 30 patients , 23 ( 76.7 % ) were classified as having MSA - C and seven ( 23.3 % ) were diagnosed with MSA - P. - pubmed
Twenty - one patients complained of sleep disorders . - pubmed
Twenty - one patients had obstructive sleep apnea . - pubmed
CONCLUSIONS : Various sleep disorders are common in Chinese MSA patients . - pubmed
House finch populations differ in early inflammatory signaling and pathogen tolerance at the peak of Mycoplasma gallisepticum infection . - pubmed
Periodontitis is an inflammatory disease of microbial origin , resulting in devastation of the tooth supporting apparatus . - pubmed
There is miniscule literature regarding the contribution of AGE to periodontal disease in patients with DM . - pubmed
Dibenzoyl and isoflavonoid glycosides from Sophora flavescens : inhibition of the cytotoxic effect of D - galactosamine on human hepatocyte HL-7702 . - pubmed
Compounds 1 , 2 , 13 , 14 , and 19 exhibited weak inhibition of the cytotoxic effect of d - galactosamine on the human hepatic cell line HL-7702 . - pubmed
MicroRNAs define distinct human neuroblastoma cell phenotypes and regulate their differentiation and tumorigenicity . - pubmed
BACKGROUND : Neuroblastoma ( NB ) is the most common extracranial solid tumor in children . - pubmed
Resting - state brain activation correlates with short - time antidepressant treatment outcome in drug - naive patients with major depressive disorder . - pubmed
OBJECTIVE : A resting - state functional magnetic resonance imaging study ( fMRI ) to investigate pretreatment regional differences in brain function , in patients with early treatment responsive ( ERD ) and early treatment nonresponsive ( END ) major depressive disorder ( MDD ) . - pubmed
METHODS : Patients with MDD and healthy control subjects underwent fMRI . - pubmed
Brain activity in patients with ERD ( n = 26 ) differed from those with END ( n = 30 ) in the lingual gyrus and cerebellum . - pubmed
There was a significantly correlation between activity in these regions and disease duration in patients with ERD , and with amelioration of depressive symptoms in patients with END . - pubmed
A preemptive management approach to patients at high risk of relapse is more effective . - pubmed
SUMMARY : Allogeneic haematopoietic stem cell transplantation is curative in up to 40 % of myelodysplastic syndrome patients . - pubmed
Biopsy Gleason score & gt;= 8 was the most common cause for classification of patients into the high - risk PCa group . - pubmed
Prediction of coronary artery disease in patients with lower extremity peripheral artery disease . - pubmed
Coronary artery disease ( CAD ) is a major determinant of long - term prognosis in patients with peripheral artery disease ( PAD ) . - pubmed
We investigated the predictors of CAD in patients with lower extremity PAD.A total of 107 patients with PAD who underwent peripheral and simultaneous coronary angiography were reviewed . - pubmed
The prevalence of CAD in patients with PAD was 62 % ( 67/107 ) , and of this 62 % , only 13 % ( 9/67 ) had angina and 72 % ( 48/67 ) had multi - vessel disease . - pubmed
The patient experienced convulsions , and the 24 - h ambulatory electroencephalography results showed abnormalities , but the electromyography results were normal . - pubmed
OBJECTIVES : Cytotoxic effects of obturation materials were tested in presence and absence of endotoxin on human monocytes in vitro . - pubmed
BACKGROUND : Breast surgery compromises one of the most common cancer surgeries in females and commonly followed by acute postoperative pain . - pubmed
We assumed that pregabalin and ketamine can be used in control of postoperative pain in female patients undergoing breast cancer surgery . - pubmed
All patients received general anesthesia and after recovery , the three groups were assessed in the first postoperative 24 h for postoperative visual analog scale ( VAS ) , total 24 h morphine consumption , incidence of postoperative nausea and vomiting ( PONV ) , sedation score & gt;2 and any complications from the drugs used in the study . - pubmed
Safety , efficacy , and pharmacokinetics of navitoclax ( ABT-263 ) in combination with erlotinib in patients with advanced solid tumors . - pubmed
This phase I study ( NCT01009073 ) evaluated the safety , pharmacokinetics , and preliminary antitumor activity of navitoclax combined with erlotinib in patients with advanced solid tumors . - pubmed
Patients with documented cancers for whom erlotinib therapy was appropriate received erlotinib 150 mg orally once daily plus navitoclax 150 mg orally once daily , with navitoclax dose escalation via a continuous reassessment method model . - pubmed
RESULTS : Eleven patients were enrolled , including six patients with nonsmall cell lung cancer . - pubmed
Dose - limiting toxicities , most commonly diarrhea , were observed in 4 patients . - pubmed
The respiratory DC / macrophage network at steady - state and upon influenza infection in the swine biomedical model . - pubmed
Human and mouse respiratory tracts show anatomical and physiological differences , which will benefit from alternative experimental models for studying many respiratory diseases . - pubmed
Pig has been recognized as a valuable biomedical model , in particular for lung transplantation or pathologies such as cystic fibrosis and influenza infection . - pubmed
Interestingly , porcine moDCs increased in the lung upon influenza infection , as observed in the mouse model . - pubmed
METHODS : Two groups of patients were screened retrospectively over a 5 - year period for the inclusion criterion of severe retrobulbar hematoma after retrobulbar or parabulbar injection . - pubmed
Although osteoarthritis can affect all joints , knee osteoarthritis is the most common type among adolescents . - pubmed
We established a new ' transmission kinetic assay ( TKA ) ' to quantify the human cytomegalovirus ( HCMV ) transmission between cells in vitro and to phenotypically characterize HCMV strains based on their mode of transmission by flow cytometric analysis . - pubmed
Autologous hematopoietic stem cell transplantation ( HSCT ) is a very effective treatment option for patients with severe systemic sclerosis ( SSc ) . - pubmed
As transfection efficiency in some primary and established cells is low , lentivirus based expression systems with high infection rates can improve experimental design . - pubmed
We provide detailed protocols for the generation of CSC293Ts and for the production of lentivirus for CSC infection using glioblastoma as a model . - pubmed
MATERIAL AND METHODS : A total of 32 participants with edentulism were included . - pubmed
We have validated this method in a chemo - genetic zebrafish model of dopaminergic neuron degeneration . - pubmed
Pseudomonas aeruginosa and Aspergillus fumigatus are the leading bacterial and fungal pathogens in cystic fibrosis ( CF ) . - pubmed
Patients with beta thalassemia major may develop a specific osteoarthropathy as they approach the second and third decades of life . - pubmed
Twenty - five of 50 patients between the ages of 5 and 33 years had evidence of periarticular disease that consisted of dull - aching ankle pain exacerbated by weight bearing and relieved by rest . - pubmed
Acute toxicity of phosphate ester mixtures to invertebrates and fish . - pubmed
Studies of human semen in topical corticosteroid - treated and in methotrexate - treated psoriatics . - pubmed
Ejaculates were studied from ten men with severa psoriasis treated with topical corticosteroids and from ten similar patients who had received methotrexate therapy from 1 to 9 years . - pubmed
The effect of acupuncture needling in hindlimb points on the threshold of pain arising from the radiant heat applied to the snout of the rabbit has been evaluated both before and after various surgical lesions produced in the spinal cord . - pubmed
Fibroblasts from affected and unaffected skin sites of patients with PSS and from normal adult skin were cultured in the presence of various human sera or conditioned media . - pubmed
Serum and peritoneal fluid from women with and without evidence of endometriosis were tested for the presence of antibodies against endometrial tissue antigens with Western blot analysis . - pubmed
The patients with endometriosis had serum antibodies against 34 - kd endometrial cytosolic antigen , which was not present in serum from fertile women without endometriosis . - pubmed
The peritoneal fluid from patients with endometriosis also reacted with 34 - kd endometrial antigen but not the peritoneal fluid from control fertile women . - pubmed
Percutaneous cardiopulmonary support system ( PCPS ) was applied for a 85 years old man with circulatory collapse caused by left ventricular free wall blow out rupture following acute anterior myocardial infarction . - pubmed
The patient was transferred to operating room and closure of the ventricular rupture was performed under the usual cardiopulmonary bypass . - pubmed
Adult ( 2 to 3 months old ) hypophysectomized rats were treated intratesticularly with increasing doses of 5 alpha - dihydrotestosterone ( DHT ; 10 - 200 micrograms/100 g body weight ) or vehicle ( 50 microliters dimethyl sulphoxide ; DMSO ) in the contralateral testis . - pubmed
[ Pharmacological support in dental treatment of hemophiliac patients ] . - pubmed
During a 4 - year period , 83 pregnant women with fetal choroid plexus cysts were investigated in our unit . - pubmed
The effect of magnesium sulphate ( MgSO4 ) infusion on blood pressure and circulating venous catecholamine levels in 8 patients with severe gestational proteinuric hypertension is described . - pubmed
The literature mentions its occurrence in patients subjected to aortic valve replacement who have low cardiac output and in patients undergoing myocardial revascularization . - pubmed
A randomized clinical study of patients with advanced epithelial ovarian cancer after debulking surgery showed that high - dose ( 120 mg / m2 ) cis - platinum ( DDP ) in combination with cyclophosphamide ( 600 mg / m2 ) had a significantly higher response and survival rate than the low - dose DDP ( 60 mg / m2 ) and cyclophosphamide combination . - pubmed
Though moderate to severe marrow toxicity was evident in 80 % of the patients in the high - dose group and 40 % of the low - dose group , no serious sepsis or death developed as a result of the marrow depression . - pubmed
Mild neurotoxicity was observed in 55 % of the patients in the high - dose group and only 20 % in the low - dose group . - pubmed
Mild nephrotoxicity was seen in 25 and 17 % of patients in the high- and low - dose groups , respectively . - pubmed
However , it should only be used in institutions with supportive facilities in the management of patients with severe marrow depression . - pubmed
The effect of selective intracoronary antiarrhythmic drug infusion on inducibility of cardiac arrhythmias was studied in 3 patients with recurrent sustained monomorphic ventricular tachycardia referred for comprehensive electrophysiologic studies . - pubmed
Each patient had evidence of prior myocardial infarction , 1 or more occluded coronary arteries and a readily identifiable collateral vessel that provided collateral flow to the infarct - related artery . - pubmed
In each patient , the clinical arrhythmia was reproducibly inducible by programmed stimulation in the control state . - pubmed
In each patient the clinical arrhythmia was rendered noninducible during selective intracoronary drug infusion . - pubmed
On follow - up , four patients had died of their disease , one developed recurrence and pulmonary metastases , one was free of disease after 4 years , and one is a recent case . - pubmed
Chemotherapy protocols may need to be altered to include sarcoma - oriented drugs for this particular group of patients . - pubmed
A placebo - controlled , double - blind study of 63 inpatients with major affective disorder was performed to compare the safety and efficacy of fluvoxamine and imipramine . - pubmed
Although low - dose soluble aspirin can be recommended as a useful anti - thrombotic drug regimen in patients with vascular disease , enteric - coated preparations have a theoretical advantage for aspirin preparations which are to be ingested daily for many years . - pubmed
The intense antifibrillatory and antiarrhythmic actions of GS 015 , a derivative of the novel structure series of the 5 -( beta - aminoacyl )- 3 - carbalkoxyamino - iminodibenzyles , are demonstrated on models of myocardial ischaemia : antifibrillatory action on the acute coronary occlusion in the conscious rat ( 1.0 mg / kg i.v . ) - pubmed
The substance seems suitable for preventing terminal arrhythmias in patients with ischaemic heart disease as well as for treating arrhythmias in the acute stage of myocardial infarction . - pubmed
The patient also presented with oesophageal diverticulum and hiatal hernia . - pubmed
Electron microscopic study of leucocytic infiltration of the mammary teat duct during infection with Staphylococcus aureus . - pubmed
Leucocytic response to Staphylococcus aureus infection was observed in the bovine mammary teat duct using transmission electron microscopy . - pubmed
Dermal connective tissue in patients with chronic obstructive airways disease . - pubmed
Electron microscopic study of spontaneous mammary carcinomas in cats and dogs : virus - like particles in cat mammary carcinomas . - pubmed
[ 2 cases of purulent meningitis caused by Neisseria flavescens in the same environment ] . - pubmed
Pronounced stimulation of citrate metabolism by glutamate was demonstrated in 12 of 13 strains of N. - pubmed
meningitidis tested and only 1 of 6 strains of N. - pubmed
The remaining strains of N. - pubmed
Insulin resistance in genetically obese , hyperglycemic mice . - pubmed
A case of abomasal inpaction in a cow . - pubmed
[ Current status of diet and drug therapy of diabetes mellitus in children ] . - pubmed
Sixty - one were atopic and 15 had anaphylaxis due to bee stings or drugs . - pubmed
A series of 47 children with absence seizures was analysed retrospectively . - pubmed
Fourteen of these children also had other types of seizures , and four had repeated episodes of absence status . - pubmed
A 100 % reduction in seizure frequency was achieved in 38 children ( 80.8 % ) . - pubmed
VPA was superior in the treatment of children who had EEG polyspikes or absence status . - pubmed
A seizure reduction of 50 % to 75 % was achieved in 7 children ( 14.9 % ) . - pubmed
Two patients ( 4.3 % ) had refractory seizures . - pubmed
A transient Stevens - Johnson syndrome occurred in a patient treated with ESM . - pubmed
Objective evidence of antitumor activity was seen in non - Hodgkin ' s lymphoma , chronic lymphocytic leukemia , Hodgkin ' s disease , breast cancer , and melanoma , indicating that IFL - rA , the first genetically engineered biological response modifier available for testing in cancer patients , is biologically active in vivo . - pubmed
Among 35 patients , abortion occurred spontaneously or was performed electively in 25.7 % , and 71 % of the remainder underwent delivery before 37 weeks . - pubmed
We concluded that perinatal outcome has significantly improved for diabetic women with nephropathy . - pubmed
History and physical examination in acute pulmonary embolism in patients without preexisting cardiac or pulmonary disease . - pubmed
The history and physical examination were assessed in 215 patients with acute pulmonary embolism uncomplicated by preexisting cardiac or pulmonary disease . - pubmed
[ Rat brain gangliosides under the combined effect of hypercapnia , hypoxia and hypothermia ] . - pubmed
This study describes the regional distribution in the canine atria of electrophysiologic effects induced by stimulation of the right and left cervical vagosympathetic complexes , the right atrial ganglionated plexus , and the right and left stellate ganglia . - pubmed
To quantify the dose - response relation of irritant - induced erythema , we examined inflammation in human skin after application of an irritant , using perpendicular polarized photography and diffuse reflectance spectroscopy as compared to clinical visual scoring . - pubmed
Yet in groups at high risk for HIV serology is not sufficient because of the window period between infection and seroconversion . - pubmed
These new assays to detect HIV immunity enable us to identify two new groups among seronegative , at risk individuals ; namely those with immunity to HIV and a detectable HIV infection ( silent carriers ) , and those with immunity and no proof of infection . - pubmed
Most importantly , rat - derived NK cells were functional in both YAC tumor cytolysis and ADCC assays , suggesting that the xenogeneic mouse host environment was sufficient to support the generation , maturation , and function of rat - derived NK cells . - pubmed
Evaluation of cell death in EBV - transformed lymphocytes using agarose gel electrophoresis , light microscopy and electron microscopy . - pubmed
Recently we treated several patients with limited facial injuries in which the nasoethmoidal complex " greensticks . " - pubmed
Could serum HBV DNA level in the early phase of acute hepatitis B predict evolution to chronic HBV carriage ? - pubmed
By using this analytical method , MTIC was quantified in plasma of cancer patients ( n=12 ) within 0.25 - 12 h after oral administration of temozolomide at 150 mg / m2 . - pubmed
The subjects consisted of 20 patients with skull - base meningiomas , and were classified into a preoperative embolized group and a non - embolized group . - pubmed
Apoptotic cell death in patients with sepsis , shock , and multiple organ dysfunction . - pubmed
OBJECTIVES : The purpose of this study was to determine whether apoptosis is a major mechanism of cell death in patients with sepsis . - pubmed
DESIGN : A prospective study of 20 patients who died of sepsis and multiple organ dysfunction was performed . - pubmed
The control group of 16 patients consisted of critically ill , nonseptic patients who were evaluated either prospectively ( 7 ) or retrospectively ( 9 ) . - pubmed
In addition , normal colon sections from seven patients who had bowel resections were included . - pubmed
PATIENTS : Critically ill patients . - pubmed
Indirect evidence of lymphocyte apoptosis in septic patients included extensive depletion of lymphocytes in white pulp and a marked lymphocytopenia in 15 of 19 patients . - pubmed
There were no significant differences in the overall incidence or treatment of intracranial hypertension between patients who were treated with therapeutic hypothermia and normal controls . - pubmed
Therapeutic hypothermia maintained the ICP at lower levels during the cooling phase , but once patients were rewarmed , the ICP elevated to the levels of normothermic patients . - pubmed
The absence of cardiac and circulatory function causes severe edema in amphibian embryos . - pubmed
Mechanical hyperalgesia was measured as paw withdrawal threshold ( PWT ) in response to a mechanical stimulus in two animal models of persistent pain ; ( 1 ) 24 h following subplantar injections of Freund 's complete adjuvant ( FCA ) into the left hind paw or ( 2 ) 11 - 15 days following a partial ligation of the left sciatic nerve . - pubmed
In patients with severe MTHFR deficiency , a metabolite(s ) other than hyperhomocyst(e)inemia also appears to be associated with its clinical manifestation in cerebrovascular disease . - pubmed
Semen and serum pharmacokinetics of zidovudine and zidovudine - glucuronide in men with HIV-1 infection . - pubmed
STUDY OBJECTIVE : To characterize the concentration - time profiles of zidovudine and zidovudine - glucuronide in semen and serum of men infected with the human immunodeficiency-1 virus ( HIV-1 ) . - pubmed
PATIENTS : Four asymptomatic HIV-1 - infected men . - pubmed
A 60 - year - old man underwent anterior resection for advanced rectal carcinoma . - pubmed
The patient remained disease - free for 10 months postoperatively , until multiple lung metastases appeared . - pubmed
We conclude that patients with solitary adrenal metastasis may benefit from surgical resection and that resection could be considered as a therapy for solitary adrenal metastasis from colorectal carcinoma . - pubmed
The process of interaction of the Choachi strain of Trypanosoma rangeli with intestinal epithelial cells of Rhodnius prolixus was analyzed in experiments carried out in vitro and in vivo . - pubmed
A case of disseminated infection with Pichia ohmeri . - pubmed
Multiple locations of ESBC were observed in seven patients ( 20 % ) . - pubmed
Local recurrence was observed within 4 years in 10 patients ( 28 % ) . - pubmed
CONCLUSION : Our results suggest that cryotherapy is an effective method of treatment in patients with ESBC . - pubmed
MATERIALS AND METHODS : To analyse a case of a patient suffering from this congenital malformation , her progressive clinical state , the surgical approach . - pubmed
a 42 - year - old woman , suffers from a cerebello - spino - medullar disturbance responsible for a major dependence and respiratory insufficiency with a risk of death . - pubmed
BACKGROUND : A recent Intergroup trial demonstrated a significant survival advantage of postgastrectomy chemoradiation in gastric cancer patients , primarily because of a reduction of a relative locoregional recurrence ( LRR ) rate exceeding 70 % in control patients . - pubmed
METHODS : Information on patients undergoing gastrectomy for potentially curable gastric cancer between 1990 and 2000 was reviewed . - pubmed
The effect of stimulus duration on the mismatch negativity of the auditory event - related potentials was studied in healthy children and those with attention - deficit symptoms . - pubmed
Similar analysis of human mesothelioma tumor tissue showed that , with few exceptions , receptor gene expression was substantially less than that for the carrier gene . - pubmed
Our studies have , for the first time , suggested that alcohol consumption alone does not lead to the development of marked liver necrosis ( at least in the rat ) , but rather that a second insult is required for this to occur . - pubmed
Total antioxidant capacity was determined using oxygen absorbance capacity assay ( ORAC ) in serum of patients suffering from depression , schizophrenia , Alzheimer ' s disease ( AD ) , anorexia nervosa , Parkinson ' s disease ( PD ) , amyotrophic lateral sclerosis ( ALS ) , Aids - encephalopathy , diabetic polyneuropathy ( PNP ) , cardiomyopathy ( CM ) , renal disease , and healthy individuals as controls ( C ) . - pubmed
In serum of patients with renal disease significantly elevated antioxidant capacity was found . - pubmed
Decrease of serum antioxidant capacity in patients with anorexia nervosa and Aids - encephalopathy are probably due primarily to malnutrition and secondly to insufficient antioxidant and immune system . - pubmed
There was only 1 ( 4 % ) intraoperative complication , which occurred in the second patient operated on with this procedure . - pubmed
Concerning the technique , we believe that LAO with intact spermatic vessels could be considered the treatment of choice in the patient with IAT , as it does not affect normal testicular vascularization . - pubmed
Patients presenting for initial access evaluation in contemporary practice are less likely to have arteries and veins suitable for native fistula ( AVF ) formation in the classic location . - pubmed
Seasonal changes in the physiology of male Virginia opossums ( Didelphis virginiana ): signs of the Dasyurid semelparity syndrome ? - pubmed
Treatment of human and experimental anthrax with tetracycline . - pubmed
PALMITATE UTILIZATION IN OBESE - HYPERGLYCEMIC MICE . - pubmed
Human tumor transplants in hamsters : their usefulness in the study and treatment of patients with cancer . - pubmed
METHODS AND RESULTS : One hundred ninety - eight guinea pigs ( 850 - 1,050 g ) received 30 episodes of ventricular fibrillation followed by transthoracic defibrillation . - pubmed
Health education , mass chemotherapy and the sanitary disposal of faeces have been the traditional mainstays of hookworm control , but more recently chemotherapy targeted only to heavily infected individuals who appear predisposed to hookworm anaemia has emerged as a realistic alternative . - pubmed
Continuous muscle stretch prevents disuse muscle atrophy and deterioration of its oxidative capacity in rat tail - suspension models . - pubmed
The objective of this report is to emphasize the efficacy of the oxaliplatin/5 - fluorouracil / leucovorin regimen ( FOLFOX-4 ) in three patients presenting oncologic emergencies secondary to advanced colon cancer . - pubmed
The first case was a 40 - year - old man with severe respiratory insufficiency due to massive carcinomatous lymphangitis ; subsequently a cecal adenocarcinoma was diagnosed . - pubmed
The second case was a 41 - year - old woman presenting with fever , abdominal mass and pain . - pubmed
The patient 's condition deteriorated with intestinal obstruction secondary to the large left liver mass . - pubmed
The third case was a 58 - year - old woman presenting with hepatic mass , fever and weight loss . - pubmed
These cases demonstrate that even patients with advanced colorectal cancer presenting with oncologic emergencies and life - threatening conditions can be successfully treated with the FOLFOX-4 regimen . - pubmed
A microscopic itch mite ( Pyemotes herfsi ) was identified as the likely cause of the outbreak , which affected an estimated 54 % of the Crawford County population ( 2000 population : 38,242 ) . - pubmed
In vivo , we compared the bone resorption and bone formation response to T3 in ADOI patients and age- and sex - matched controls . - pubmed
We report a 53 - year - old man , with an unusual phenotype of CTX . - pubmed
Vibrio parahaemolyticus , a gram - negative marine bacterium , is an important pathogen causing food - borne gastroenteritis or septicemia . - pubmed
Recent genome sequencing of the RIMD2210633 strain ( a Kanagawa phenomenon - positive clinical isolate of serotype O3 : K6 ) revealed that the strain has two sets of gene clusters that encode the type III secretion system ( TTSS ) apparatus . - pubmed
To match the patients with IP and unique patients with OP , logistic regression was used to develop a propensity score . - pubmed
Patients with IP were matched to unique patients with OP with an identical 5 - digit propensity score . - pubmed
METHODS : Homocysteine concentrations were measured in 30 XFS / XFG patients and 18 age matched controls . - pubmed
In XFS / XFG patients homocysteine concentration was significantly elevated ( unpaired t test , p = 0.023 ) , and CCA stiffness was higher ( p<0.05 ) , while strain , cross sectional compliance coefficient , distensibility , and BRS were significantly reduced compared to the controls ( Mann - Whitney U test , p< ; or = 0.013 for each parameter ) . - pubmed
Effect of linear polarized light irradiation near the stellate ganglion in skin blood flow of fingers in patients with progressive systemic sclerosis . - pubmed
OBJECTIVE : The purpose of this study is to evaluate the effect of linear polarized light irradiation near the stellate ganglion area on cutaneous blood flow in fingers of patients with progressive systemic sclerosis . - pubmed
BACKGROUND DATA : Sympathetic overactivity is known to be present in patients with progressive systemic sclerosis . - pubmed
METHODS : Five patients with progressive systemic sclerosis and three normal healthy controls were studied . - pubmed
RESULTS : No significant alternations of the skin blood flow between normal controls and patients with progressive systemic sclerosis after linear polarized light irradiation were detected . - pubmed
The effect of linear polarized light on the microcirculation of patients with progressive systemic sclerosis was minimal and transient . - pubmed
CONCLUSION : The effect of linear polarized light in treating patients with progressive systemic sclerosis may not result from the improvement of skin blood flow . - pubmed
A 65 - year - old woman with a left occipital lobe tumor . - pubmed
[ Analysis of postoperative complications of radical hysterectomy for 219 cervical cancer patients ] . - pubmed
OBJECTIVE : To analyze the causes and therapeutic approaches for the complications of radical hysterectomy plus pelvic lymphadenectomy in cervical cancer patients . - pubmed
RESULTS : a total of 49 patients ( 22.4 % ) developed postoperative complications . - pubmed
The patients in the group treated by radical hysterectomy plus pelvic lymphadenectomy was likely to develop postoperative complication compared with the patients in the group by modified radical hysterectomy plus pelvic lymphadenectomy ( 24.0 % versus 0 , P = 0.067 ) . - pubmed
The postoperative complication incidence in the patients who had preoperative neoadjuvant chemotherapy through intra - arterial catheter or radical radiotherapy in the other hospitals were 50.0 % ( 2/4 ) and 100.0 % ( 1/1 ) , which were higher than that of the patients treated primarily in our hospital ( 21.3 % , 25.3 % ) though without statistically significant difference among the groups . - pubmed
On the example of a 5 - year longitudinal study of a boy who suffered severe traumatic brain injury , it is shown that there seems to be no limit as to the repair of the injured central nervous system ( CNS ) if Schalow Coordination Dynamics Therapy is administered . - pubmed
This study examined asthma morbidity in relation to mold , cockroach , dust mite , and cat allergens in the homes of 61 low - income Chicago children with asthma . - pubmed
Spontaneous polymorphic ventricular tachycardia after administration of pilsicainide in a patient resuscitated from ventricular fibrillation . - pubmed
We performed a pilsicainide challenge test in a 38 - year - old man who was resuscitated from ventricular fibrillation without apparent baseline electrocardiogram ( ECG ) abnormality . - pubmed
Low selenium levels have been associated with anemia in animals , but this relationship has not been well characterized in humans . - pubmed
METHODS : One eye each of 40 healthy subjects , 48 glaucoma patients , and six patients with ocular hypertension were measured with SLP - VCC and CSLO . - pubmed
Four glaucoma specialists , four general ophthalmologists , four residents in ophthalmology , and four optometrists classified the ONH photographs as normal or glaucomatous . - pubmed
Role of pre - infarction angina and inflammatory status in the extent of microvascular obstruction detected by MRI in myocardial infarction patients treated by PCI . - pubmed
Our study aimed to investigate the incidence and the influencing factors of MVO in patients with ST - elevation myocardial infarction ( STEMI ) treated by primary percutaneous intervention ( PCI ) . - pubmed
PATIENTS , METHODS : Using contrast - enhanced MRI , microvascular obstruction was defined as early hypoenhancement . - pubmed
50 patients ( 56+/-11 years ) with STEMI underwent PCI . - pubmed
RESULTS : Microvascular obstruction ( score 1 to 3 ) was observed in 90 % of the patients and major microvascular obstruction ( score 2 - 3 ) in 54 % . - pubmed
Water stress augments silicon - mediated resistance of susceptible sugarcane cultivars to the stalk borer Eldana saccharina ( Lepidoptera : Pyralidae ) . - pubmed
All patients were women , aged 52 to 63 years and presented with single or multiple pulmonary nodules . - pubmed
The study cohort comprised 64 FMF patients who were classified as attack - free patients ( Group 1 ; n = 34 patients , aged 3 - 19 years ) and attack patients ( Group 2 ; n = 30 patients , aged 3 - 21 years ) . - pubmed
Inflammation with increased acute phase reactants continued during both attack and attack - free periods in FMF patients . - pubmed
METHODS : We developed a modified model of chronic antigen - induced arthritis ( AIA ) in mice with a strong bias toward inflammation . - pubmed
RESULTS : In this novel model of AIA , mice developed organized ectopic lymphoid follicles with topologically segregated B cell and T cell areas , high endothelial venules , and germinal center formation within the chronically inflamed synovial tissue . - pubmed
For example , knowledge of the pathways involved in the development of endothelial dysfunction or in endothelial repair associated with bone marrow - derived cells -- a common feature of a number of cardiovascular conditions -- could lead to treatments that are able to stimulate endothelial replacement with circulating progenitor cells in patients with pulmonary arterial hypertension of whatever etiology . - pubmed
Follow - up PET scans were negative for abdominal malignancy in 38 patients . - pubmed
Thirty - five of these 38 patients with negative follow - up PET were proven to be without abdominal malignancy , with a negative predictive value of 92.1 % ( 35 of 38 ) . - pubmed
Fifteen of these 17 patients with a positive follow - up PET scans were found to have malignancy in the abdomen with a positive predicative value of 88.2 % ( 15 of 17 ) . - pubmed
All 4 patients with indeterminate follow - up scans were proven not to have malignancy . - pubmed
We studied 99 patients discharged from the department between March and December 2002 with a HF diagnosis and samples of cTnI. - pubmed
Patients with acute coronary syndromes , myocarditis or renal failure were excluded . - pubmed
We report the clinical and molecular characteristics of 6 new patients with recessive hereditary methemoglobinemia due to cytochrome b5 reductase deficiency . - pubmed
One patient was affected by Type - II disease with cyanosis and severe progressive neurological dysfunction , whereas the others displayed the benign Type - I phenotype . - pubmed
The RNA alphavirus Semliki Forest ( SFV ) triggers apoptosis in various mammalian cells , but it has remained controversial at what infection stage and by which signalling pathways host cells are killed . - pubmed
The recombinant strain of Bacillus subtilis bearing B. - pubmed
METHODS : The study included 21 patients ( 12 males , 9 females ; mean age 45 years ; range 19 to 72 years ) with tennis elbow . - pubmed
The patients were evaluated with a pain score ( 0 to 10 points ) and clinical examination before and one month after treatment . - pubmed
RESULTS : Complete or near - complete relief of pain and unlimited function were obtained in four patients ( 40 % ) in group 1 , and in 10 patients ( 90.9 % ) in group 2 . - pubmed
On physical examination , two patients ( 20 % ) in group 1 and eight patients ( 72.7 % ) in group 2 were pain - free upon pressure on the lateral epicondyle or dorsiflexion of the wrist . - pubmed
OB glue paste technique for establishing nude mouse human gastric cancer orthotopic transplantation models . - pubmed
METHODS : Using OB glue paste technique , orthopic transplantation models were established by implanting SGC-7901 and MKN-45 human gastric cancer cell strains into the gastric wall of nude mice . - pubmed
The biological behaviors of the nude mouse human gastric cancer orthotopic transplantation models established with this technique are similar to the natural processes of growth and metastasis of human gastric cancer , and , therefore , can be used as an ideal model for experimental research of proliferative metastasis of tumors . - pubmed
BACKGROUND : Bariatric surgery achieves long - term weight loss in obese adults with amelioration of diabetes and hypertension . - pubmed
RESULTS : The baseline ( preoperative ) mean age was 46 years , 82 % were women , 26 had a blood pressure of & gt ; or = 140/90 mm Hg , and 25 had type 2 diabetes . - pubmed
Selection for body weight at 49 day of age ( s and h , downward selected lines ; s ' and h ' , upward selected lines ) affected reproductive traits in CF1 mice lines . - pubmed
In general , 25 % of the patients develop metastasis . - pubmed
None of these patients developed metastasis . - pubmed
Seventeen patients were described to have melanocytic schwannoma of the skin or subcutaneous tissues . - pubmed
Two of the three patients showed metastatic disease , one of them died of disseminated metastases . - pubmed
Owing to the lack of clinical trials , we recommend that patients be treated according to the existing guidelines for melanoma . - pubmed
The first and most important action on encountering a patient with unexplained gastric or duodenal ulceration is to double check that they are truly H. - pubmed
Visual impairment was considered absent in 87 patients ; mild in 52 ; moderate in 17 ; and 22 patients were legally blind . - pubmed
The results clearly demonstrate that it is possible to perform a complete evaluation of visual function and ocular health in the elderly institutionalized patient , independent of age , cognitive status , or communication disorders . - pubmed
METHODS : A cross - sectional survey with serological testing for HIV , syphilis , HBV and HCV through long - chain referral sampling strategy to help control the bias generated from non - statistic sampling . - pubmed
Supplementation with cholecalciferol does not improve glycaemic control in diabetic subjects with normal serum 25 - hydroxyvitamin D levels . - pubmed
CONCLUSIONS : We were not able to demonstrate that vitamin D supplementation had a significant effect on glucose metabolism in subjects with type 2 diabetes but without vitamin D deficiency . - pubmed
Further studies are needed in larger groups of subjects with type 2 diabetes or impaired glucose tolerance , who also exhibit low serum 25 - hydroxyvitamin D levels . - pubmed
The DNA - DNA hybridization value between strain YIM 65188 ( T ) and S. - pubmed
is proposed , with YIM 65188 ( T ) (= CCTCC AA 208020(T ) = DSM 41942(T ) ) as the type strain . - pubmed
Virus infection is one of the major threats to human health and can be avoided by minimizing exposure to infectious viruses . - pubmed
Image - based non - destructive methods were used to quantify root growth reactions happening within hours following simulated leaf herbivore attack.1 The induction of wound reactions in leaves of seedlings of Nicotiana attenuata led to transiently decreased root growth rates : Upon application of the oral secretions and regurgitants of the specialist herbivore Manduca sexta , a transient decrease in root growth was observed that was more pronounced than if a mere mechanical wounding was imposed . - pubmed
MATERIALS AND METHODS : A total of 750 children of rural areas in the age group of 6 - 10 years were examined , using WHO index , to record the prevalence of dental caries and treatment needs . - pubmed
To evaluate the clinical usefulness of noninvasive positive pressure ventilation ( NPPV ) in liver transplant recipients , we established application criteria for NPPV in respiratory management in these patients , as follows : ( 1 ) arterial oxygen tension to fraction of inspired oxygen ratio less than 300 and arterial carbon dioxide tension greater than 45 mm Hg ; ( 2 ) arterial oxygen tension to fraction of inspired oxygen ratio less than 200 ; ( 3 ) respiratory rate greater than 25 / min ; and ( 4 ) presence of severe atelectasis or pulmonary edema . - pubmed
In 1 patient , reintubation was required because of deterioration of respiratory function due to systemic infection . - pubmed
OBJECTIVE : To search for novel autoantibodies in patients with rheumatoid arthritis ( RA ) in an effort to better understand the processes of joint destruction in this disease . - pubmed
METHODS : A 25 - year - old woman , without medical or familiar history for hypertension or cerebrovascular diseases , underwent a normal spontaneous delivery with neonatal birth weight of 2340 g ( 9th percentile ) . - pubmed
Eight days later the patient presented sudden headache and generalized tonic - clonic seizures . - pubmed
FYX-051 showed a potent and long - lasting hypouricemic effect in a rat model of potassium oxonate - induced hyperuricemia , and it seems to be a promising candidate for the clinical treatment of hyperuricemia . - pubmed
Of the 23 patients studied , 18 presented the cardiac form and five presented the cardiodigestive form of Chagas disease . - pubmed
Echinocandin lock therapy could significantly enhance the management of candidiasis in patients with indwelling catheters by combating biofilms and enabling device maintenance in situ . - pubmed
We examined the effects of cisplatin , an anti - cancer drug , on HCs of the inner ear and on HCs and support cells ( SCs ) of neuromasts in zebrafish using transmission and scanning electron microscopy . - pubmed
Usefulness of serial determination of Aspergillus galactomannan in the diagnosis and management of invasive aspergillosis in an AIDS patient with non - Hodgkin lymphoma . - pubmed
GAG storage in untreated MPS I dogs was significantly different from normal dogs in all examined sections . - pubmed
GAG levels in normal dogs varied by region : frontal lobe ( mean : 2.36 + - 0.54 mug / mg protein ) , cerebellum ( 2.67 + - 0.33 ) , basal ganglia and thalamus ( 3.51 + - 0.60 ) , hippocampus ( 3.30 + - 0.40 ) , and brainstem ( 3.73 + - 1.10 ) . - pubmed
METHODS : Twenty - two patients who had been treated previously with cannulated screws or dynamic hip screw for femoral - neck fracture and progressed to nonunion were treated with revision internal fixation using an angle blade plate and autogenous nonvascularised fibular graft . - pubmed
Mean patient age was 38 ( range 21 - 52 ) years , with average duration between injury and revision surgery 11.2 m ( range 8 - 16 months ) . - pubmed
Patients with poor results included one with nonunion and other with avascular necrosis with collapse of the femoral head . - pubmed
Ranolazine injection into coronary or femoral arteries exerts marked , transient regional vasodilation without systemic hypotension in an intact porcine model . - pubmed
This report describes a patient presenting with recurrent acute renal failure occurring in the course of POEMS syndrome , a multisystem disease associated with plasma cell dyscrasia . - pubmed
This case report describes a 52 - year - old woman with a 10 - year history of underlying systemic lupus erythematosus with minimal proteinuria who developed sudden onset of nephrotic syndrome . - pubmed
Silent peripheral arterial disease in patients admitted to the emergency room . - pubmed
Detection during preclinical stages ( silent ) may help to identify individuals and populations at risk ( elderly patients ) for atherothrombotic disease ( stroke or coronary ) . - pubmed
Subacute toxicity assessment of carotenoids extracted from citrus peel ( Nanfengmiju , Citrus reticulata Blanco ) in rats . - pubmed
The mixture of carotenoids extracted from citrus peel ( Nanfengmiju , Citrus reticulata Blanco ) was tested for subacute oral toxicity . - pubmed
In this study , dose levels of 0 , 200 , 500 and 2000 mg / kg body weight / day were administered by gavage to 10 Wistar rats / sex / group for 28 days . - pubmed
These findings suggested that the No - Observed - Adverse - Effect Level for the mixture of carotenoids extracted from citrus peel was at least 2000 mg / kg body weight / day . - pubmed
Neuroimaging , biochemical and cellular evidence of protection by mycophenolate mofetil on middle cerebral artery occlusion induced injury in rats . - pubmed
Therefore , the present study was designed to evaluate the effect of mycophenolate mofetil ( MMF ) on the cerebral ischemic injury in the middle cerebral artery occlusion ( MCAo ) model in rats . - pubmed
One hour after MCAo , the animals were treated with MMF ( 50 , 100 , 200mg / kg , i.p . ) - pubmed
The efficacy and safety of lixivaptan in outpatients with heart failure and volume overload : results of a multicentre , randomized , double - blind , placebo - controlled , parallel - group study . - pubmed
This study assessed weight loss after 1 day and 8 weeks of treatment with lixivaptan in outpatients with HF and volume overload . - pubmed
CONCLUSIONS : In outpatients with HF and volume overload , lixivaptan 100 mg once daily , when added to standard therapy , reduced body weight , improved dyspnoea and orthopnoea , and was well tolerated . - pubmed
BACKGROUND & amp ; AIMS : New treatment approaches are needed for patients with pancreatic adenocarcinoma . - pubmed
Direct lipid extraction from wet Chlamydomonas reinhardtii biomass using osmotic shock . - pubmed
Osmotic shock treatment was applied directly to wet Chlamydomonas reinhardtii biomass with water content & gt;99 % , along with both polar and non - polar organic solvents . - pubmed
Outcome of patients with localized orbital sarcoma who relapsed following treatment on Intergroup Rhabdomyosarcoma Study Group ( IRSG ) Protocols - III and -IV , 1984 - 1997 : a report from the Children 's Oncology Group . - pubmed
RESULTS : Twenty - four of 188 patients ( 12.8 % ) developed local ( n = 22 ) or distant relapse ( n = 2 ) at 0.057 - 7.05 years ( median , 1.58 ) after enrollment . - pubmed
After recurrence , patients underwent orbital exenteration ( n = 10 ) , enucleation ( 2 ) , tumor excision ( 3 ) , or biopsy ( 1 ) ; 7 had no operation , and 1 had no data . - pubmed
Two patients died ; one at 1.79 years after contralateral brain metastasis followed by local recurrence , and another at 2.49 years after multiple local recurrences . - pubmed
Twenty - two patients ( 91.7 % ) survived sarcoma - free for 0.04 - 17 years ( median , 6.9 ) after relapse , and 18 of 22 ( 82 % ) were alive & gt;=5 years after relapse . - pubmed
No mechanism exists to predict accurately the risk of recurrence in patients with PA following successful gross total surgical resection . - pubmed
METHODS : A multicentre , retrospective cohort study of patients admitted for leg ulceration between 1996 and 2007 was conducted . - pubmed
The aims of this study were to investigate the long - term course and biological behavior of orthotopically implanted C6 gliomas and to dynamically monitor the distribution of superparamagnetic iron oxide ( SPIO ) nanocomposite - labeled C6 glioma cells in rats using 7.0 T MRI . - pubmed
DESIGN : This cross - sectional study included 151 children and adolescents 8 - 17 years old with NS from 16 participating institutions in North America . - pubmed
OBJECTIVE : To evaluate the retraction technique for urinary catheterization of women with Type III female genital mutilation ( FGM ) . - pubmed
METHODS : Male rats randomized into four groups ( n = 12 ): control , diabetic , control + resveratrol , and diabetic + resveratrol . - pubmed
Nephropathy is a common consequence of diabetes , with a high prevalence in patients with type 1 ( 15%-25 % ) and type 2 diabetes mellitus ( T2DM ; 30%-40 % ) . - pubmed
The ongoing advances in T2DM therapy may allow optimization of glycemic control in a wide range of patients , thereby helping to reduce the increasing morbidity and mortality associated with diabetic nephropathy . - pubmed
INTRODUCTION : Alveolointerstitial involvement is a common manifestation in patients with connective tissue disorders . - pubmed
MATERIAL AND METHODS : Thirty one consecutive patients with a suspected diagnosis of rheumatoid lung involvement were examined with high resolution transthoracic ultrasonography for detecting of ultrasonographic comet tail signe as a ultrasonographic marker of lung involvement in alveolointerstitial involvement in rheumatoid lung disease and the results of them were compared with High resolution computed tomography as gold standard method for diagnosis of lung involvement in this patients . - pubmed
Until now , these procedures have been reserved for low - risk patients and are rarely offered to patients with advanced disease where neoadjuvant chemotherapy and postmastectomy radiation are a planned part of the treatment . - pubmed
CONCLUSIONS : SSM and NSSM have been offered to patients with relatively low - risk breast cancer as oncologically safe while affording superior cosmesis with one - step immediate reconstruction . - pubmed
Our series demonstrates that either procedure can be offered to patients with more advanced cancers requiring postoperative RT . - pubmed
Neonatal colonization of germ - free mice with Bifidobacterium longum prevents allergic sensitization to major birch pollen allergen Bet v 1 . - pubmed
longum might be a promising candidate for perinatal intervention strategies against the onset of allergic diseases in humans . - pubmed
UNLABELLED : Neoadjuvant sunitinib might downsize unresectable renal cell carcinoma ( RCC ) and enable nephrectomy in a subset of patients . - pubmed
After neoadjuvant sunitinib in 27 RCC patients , tumors were resected in 13 patients . - pubmed
INTRODUCTION : In patients with locally advanced and metastatic RCC , selection criteria for nephrectomy are imprecise . - pubmed
CT scans of unresectable primary RCCs before and after neoadjuvant sunitinib were retrospectively reviewed to identify radiographic features associated with patient selection for surgery . - pubmed
PATIENTS AND METHODS : CT scans of 27 patients with RCC ( 31 tumors ) treated with neoadjuvant sunitinib were performed as part of a prospective clinical trial . - pubmed
After neoadjuvant sunitinib , tumors were surgically resected in 13 patients ( 17 tumors ) and not resected in 14 patients ( 14 tumors ) . - pubmed
Eligible patients had to be over 16 years of age , consulted within 72 hours for a trauma , and available for outpatient follow - up at 2 , 7 , and 14 days posttrauma . - pubmed
OBJECTIVE : The aim of this study was to evaluate the detection rate accuracy of Double - balloon Enteroscopy ( DBE ) after Capsule Endoscopy ( CE ) in patients with suspected small bowel diseases . - pubmed
METHODOLOGY : From January 2009 to March 2012 , sixty - two patients with obscure small bowel diseases who underwent CE followed by DBE were included in this study . - pubmed
Furthermore , the detection rate of small bowel diseases in patients with obscure small intestinal bleeding using CE + DBE ( 90.9 % , 30/33 ) was superior to that of CE ( 78.8 % , 26/33 ) ; chi(2)=1.8857 , P>0.05 . - pubmed
Using of CE followed by DBE is effective in the diagnosis and management of patients with obscure small bowel diseases . - pubmed
The most common indication for 1 - step PEG placement was swallowing dysfunction in children with neurological impairment ( 49 % ) . - pubmed
Direct - acting antiviral agents in patients with hepatitis C cirrhosis . - pubmed
Patients with cirrhosis who are infected with hepatitis C virus ( HCV ) are the most in need of antiviral treatment . - pubmed
Tissue damage on the ocular surface of patients with RA is autoimmune - mediated . - pubmed
False - positive fluorodeoxyglucose positron emission tomography results after chemotherapy in patients with metastatic seminoma . - pubmed
MATERIALS AND METHODS : Between July 2003 and September 2013 we performed 305 PC - RPLNDs in 277 patients , 22 because of metastatic seminoma . - pubmed
In 1 patient , there was uncertainty whether the initial retroperitoneal tumor contained choriocarcinoma elements . - pubmed
In 4 of 7 patients , intraoperative or postoperative complications occurred ( polar artery ligation with functional loss , bilateral non - nerve - sparing technique with retrograde ejaculation , ureteral replacement with an ileal segment , and pulmonary embolism ) . - pubmed
CONCLUSION : In patients with metastatic seminoma who received chemotherapy , FDG - PET is a valuable tool to evaluate whether the residual mass contains viable tumor tissue or only necrosis . - pubmed
, patients with ureteral compression , patients with high risk of recurrence , or patients with unclear initial histology ) . - pubmed
There was one late noncardiac death and 73 patients returned for angiography ( 82 % ) , thus 12 additional patients were lost to follow - up at 1 year . - pubmed
METHODS : Thirty participants with acute stroke who were enrolled in inpatient rehabilitation and had cognitive impairments were randomized to receive strategy training ( n = 15 , 10 sessions as adjunct to usual inpatient rehabilitation ) or reflective listening ( n = 15 , same dose ) . - pubmed
In Taiwan , the first human - infecting H6N1 avian influenza virus was isolated in 2013 . - pubmed
We report on a 17 - year - old female patient with hypertrichosis on the lumbosacral area since birth that was later diagnosed with tethered cord in magnetic resonance imaging . - pubmed
We present the case of a 18 year - old man with abdominal pain , nausea and hematemesis , the endoscopy showed polypoid tumor bleeding of 5 cm in gastric antrum . - pubmed
The aim of this study was to investigate the effect of early vessel recanalization on clinical outcome in patients with large - vessel occlusion stroke . - pubmed
METHODS : This is a single - center cohort study , analyzing prospectively collected data on 152 patients with large - vessel occlusion and acute ischemic stroke . - pubmed
RESULTS : Early recanalization was an independent predictor of a good clinical outcome in only those patients who presented with a severe ischemic stroke ( National Institutes of Health Stroke Scale [ NIHSS ] score & gt;15 ; P = .017 ) . - pubmed
This was not the case for less severe strokes ( NIHSS score & lt;= 15 ) where recanalization did not lead to more patients with functional independence at 90 - day follow - up ( P = .21 ) . - pubmed
CONCLUSIONS : In this study of acute large - vessel occlusion stroke , we found that clinical outcome following early recanalization was dependent on the patient 's pretreatment NIHSS score . - pubmed
A non - negligible proportion of patients with milder strokes did well despite persistent large - vessel occlusion . - pubmed
These results may suggest that in patients who are able to maintain adequate collateral flow despite proximal arterial occlusion , effective adaptive mechanisms are present , which for some patients are long - lasting . - pubmed
BACKGROUND : Trichomoniasis , caused by Trichomonas vaginalis , is the most common sexually transmitted disease ( STD ) in the world with estimates of 7 - 8 million infections annually in the United States and 180 million globally . - pubmed
PURPOSE : Radiotherapy ( RT ) is used frequently in patients with melanoma , but results are suboptimal because the disease is often radioresistant . - pubmed
Additionally , athymic mice with D04 flank tumours were treated with fractionated RT after gavage with trametinib and monitored for tumour growth . - pubmed
Mice receiving the combination treatment ( trametinib 1mg / kg and RT over 3 days ) showed a reduced mean tumour volume compared with mice receiving trametinib alone ( p=0.016 ) , or RT alone ( p=0.047 ) . - pubmed
Ultrastructural pathological features of unilateral renal artery stenosis in the rats . - pubmed
In this study , we aimed to investigate histopathological characteristics in a rat model of RAS . - pubmed
AIM : To analyze the expression of proapoptotic molecules in patients with lupus erythematosus discoid and lupus profundus . - pubmed
OBJECTIVE : Patients with subarachnoid haemorrhage ( SAH ) often require multidisciplinary management and their treatment is difficult to standardize . - pubmed
A nationwide registry to assess the overall management of patients treated for SAH would be useful to further investigate patients with SAH . - pubmed
MATERIALS AND METHODS : Consecutive men undergoing radical prostatectomy for histologically confirmed prostate cancer were analyzed . - pubmed
This paper reports a 25 - year follow - up of a patient with Clouston syndrome , from childhood to adulthood , monitoring diagnosis and clinical course of the disease . - pubmed
Current treatment options for hepatitis C patients co - infected with HIV . - pubmed
With the availability of all - oral , direct acting antivirals ( DAAs ) , hepatitis C virus ( HCV ) therapy has been revolutionized for HIV / HCV co - infected patients . - pubmed
Indeed HCV cure rates are now no longer different between HCV mono and HIV / HCV co - infected persons and are both greater than 95 % . - pubmed
In HIV / HCV co - infection however , drug interactions between HIV and HCV agents need be checked prior to starting HCV therapy . - pubmed
Acute Effect of Intravenous Sildenafil on Cerebral Blood Flow in Patients with Vasospasm After Subarachnoid Hemorrhage . - pubmed
We recently demonstrated that it could improve cerebral vasospasm ( CVS ) in humans after SAH . - pubmed
METHODS : Six subjects with angiographically confirmed CVS received 30 - mg of intravenous sildenafil ( mean 9 + - 2 days after aneurysmal SAH ) . - pubmed
PURPOSE : Measures derived from longitudinal tumour size data have been increasingly utilised to predict survival of patients with solid tumours . - pubmed
The aim of this study was to examine the prognostic value of such measures for patients with metastatic pancreatic cancer undergoing gemcitabine therapy . - pubmed
CONCLUSIONS : A parametric model that incorporates model - derived tumour shrinkage metrics in addition to other baseline variables could predict reasonably well survival of patients with metastatic pancreatic cancer . - pubmed
Artemisinin - Resistant Plasmodium falciparum Malaria . - pubmed
Our primary outcome was survival of OHCA patients at the end of ED stay . - pubmed
Here , we present the IND enabling preclinical rodent studies in support of clinical testing of vesicular stomatitis virus ( VSV ) as a systemic therapy . - pubmed
Efficacy studies showed dose - dependent tumor regression in C57BL / KaLwRij mice bearing syngeneic 5TGM1 plasmacytomas after systemic VSV administration . - pubmed
These findings suggest that active CMV infection in the setting of treated HIV may represent an attractive potential target for therapeutic intervention . - pubmed
METHODS : Ninety - five patients with IBS and 276 healthy controls were enrolled in the study . - pubmed
However , the response to treatment is not as robust as is seen in osteoporosis , and it seems less effective in certain types of OI , and in adult OI patients as compared to most pediatric cases . - pubmed
In this review , we will summarize the recent findings regarding the pharmacological and biological strategies for the treatment of patients with OI . - pubmed
The clinical characteristics and antibody levels were compared between patients with ( seizure group ) and without seizures ( non - seizure group ) . - pubmed
RESULTS : The non - seizure and seizure groups comprised 173 and 29 patients , respectively . - pubmed
From the clinical point of view , it is important to be aware that patients with microtia must obtain also appropriate diagnostic imaging studies of the craniovetebral junction due to eventual concomitant occipitalization of the atlas and frequently associated C1 - C2 instability . - pubmed
On the basis of the results , the researchers concluded that Tribulus terrestris can be used as a safe therapeutic alternative to current modalities for the management of motility dysfunction in males . - pubmed
Cervical artery dissection , including carotid artery and vertebral artery dissection , is associated in at least 20 % of young adult patients with stroke . - pubmed
PATIENT CONCERNS : We reported 2 patients who complained of dizziness and pain , the findings of US confirmed the presence of extracranial vertebral artery dissection . - pubmed
OUTCOMES : The patients were diagnosed of vertebral artery dissection by US . - pubmed
Testing of a novel percutaneous temporary aortic valve in a rabbit model of acute severe aortic regurgitation : an experimental study . - pubmed
The redesigned membrane - based TAV prototype is evaluated in a rabbit model of acute severe aortic regurgitation . - pubmed
Eight rabbits of body weights ranging 4.9 - 5.4 kg were randomly assigned to two groups : those received additional hemodynamic support with the TAV prototype immediately after aortic regurgitation was induced versus no TAV support . - pubmed
RESULTS : Comparing the groups with TAV versus without TAV , the mean body weights were similar : 4.99 + - 0.06 vs. 5.10 + - 0.22 kg ( p = 0.71 ) . - pubmed
CONCLUSIONS : In a rabbit model of acute massive aortic regurgitation , the use of the TAV support prototype did not hasten the animals ' death , but rather survival may be enhanced by the use of the device . - pubmed
Atheroprotective effects of statins in patients with unstable angina by regulating the blood - borne microRNA network . - pubmed
The present study investigated the protective role of statins in patients with unstable angina ( UA ) by regulating the circulating miRNA network . - pubmed
miRNA array results demonstrated that there were 21 differentially expressed miRNAs in non - statin - treated patients with UA ( n=8 ) compared with non - coronary artery disease controls ( n=8 ) , and 33 differentially expressed miRNAs in statin - treated patients with UA ( n=8 ) compared with non - statin patients . - pubmed
This study aimed to explore the effects of two siderophore - producing bacterial strains on iron absorption and plant growth of peanut in calcareous soil . - pubmed
Two siderophore - producing bacterial strains , namely , YZ29 and DZ13 , isolated from the rhizosphere soil of peanut , were identified as Paenibacillus illinoisensis and Bacillus sp . - pubmed
Therefore , YZ29 and DZ13 can be used as candidate bacterial strains to relieve chlorosis of peanut and promote peanut growth . - pubmed
PATIENTS : One hundred eighteen patients who sustained combat - related upper extremity amputations between October 2001 and December 2011 . - pubmed
CASE : A 28 - year - old woman with neurofibromatosis type 1 and acromegaly presented with absent breast development despite hormone therapy . - pubmed
Examination noted a normally developed woman with acromegalic features and Tanner stage I breasts . - pubmed
After attempting hormone therapy , patients with absent thelarche should be evaluated for congenital breast anomalies , estrogen receptor abnormalities , or gene defects . - pubmed
To investigate the effect of removal of cerebrospinal fluid by lumbar " tap test " on the cerebral circulation in patients with iNPH , 14 patients with " probable " iNPH were studied using a novel blood tracking technique based on blood oxygenation level - dependent ( BOLD ) magnetic resonance signal intensity . - pubmed
BACKGROUND : Delirium is a common and severe problem for hospitalised patients , with occurrence ranging from 14%-56 % , morbidity and mortality from 25%-33 % . - pubmed
METHODS : The bite force of 345 patients was measured with a bite force recorder ; impressions of the shape and size of the oral tori were taken on plaster models prior to orthodontic treatments . - pubmed
We present a case of a 54 - year - old man who had been followed - up for ankylosing spondylitis and presented with pain in the shoulder and pelvic girdles , restricted movement , and morning stiffness for 2 months . - pubmed
Methods A total of 136 patients ( type 1 : n = 47 , type 2 : n = 89 ) who enrolled in the study were diagnosed based on the Japanese Diabetes Society diagnostic criteria for diabetes mellitus . - pubmed
paratuberculosis ( Map ) exposed bulls of which four were intratracheally infected with a Belgian field strain of M. - pubmed
Map exposure did not interfere with the development of SIT in M. - pubmed
Chitosan - based nanoformulated ( -)- epigallocatechin-3 - gallate ( EGCG ) modulates human keratinocyte - induced responses and alleviates imiquimod - induced murine psoriasiform dermatitis . - pubmed
We investigated and compared the efficacy of nanoEGCG versus native or free EGCG in vitro and in an in vivo imiquimod ( IMQ)-induced murine psoriasis - like dermatitis model . - pubmed
The in vivo relevance and efficacy of nanoEGCG formulation ( 48 microg / mouse ) were assessed in an IMQ - induced mouse psoriasis - like skin lesion model compared to free EGCG ( 1 mg / mouse ) . - pubmed
Background : Mycoplasma hominis is often present in the amniotic cavity with microbial invasion associated with spontaneous preterm labor . - pubmed
Methods : Amniotic fluid samples were collected from 65 pregnant women ( age range : 25 - 45 years ) previously followed at an infertility clinic . - pubmed
Postoperative outcomes were evaluated , with a focus on the effects of portal vein resection and resected liver volume on remnant liver regeneration in patients with liver tumors . - pubmed
Preventive Effect of Garlic Oil and Its Organosulfur Component Diallyl - Disulfide on Cigarette Smoke - Induced Airway Inflammation in Mice . - pubmed
The aim of this study was to explore the preventive effect of garlic oil ( GO ) and its organosulfur component diallyl disulfide ( DADS ) on cigarette smoke ( CS)-induced airway inflammation . - pubmed
Anti - Carcinogenic Glucosinolates in Cruciferous Vegetables and Their Antagonistic Effects on Prevention of Cancers . - pubmed
RESULTS : Of 315 patients screened , 49 ( 15.5 % ) were randomized ( 26 to early palliative care ; 23 to the control group ) ; aged ( mean + - SD ) 71 + - 8 years ; FEV1 was 37 + - 14 % predicted ; 88 % with a COPD assessment test score & gt ; 10 ; 69 % on long - term oxygen therapy or home noninvasive ventilation . - pubmed
To characterize compatible plant pathogen interactions at early stages of infection by the obligate biotrophic fungus Podosphaera pannosa , which causes powdery mildew , and the hemibiotrophic fungus Diplocarpon rosae , which causes black spot , we analyzed changes in the leaf transcriptome after the inoculation of detached rose leaves with each pathogen . - pubmed
This report describes the surgical management of a male patient with early - stage lung cancer who underwent thoracoscopic completion right lower lobectomy after previously undergoing sublobar resection for multifocal ground glass nodules of the lung . - pubmed
On 1 - year follow - up , patient weight loss was 14 lb . - pubmed
We report the case of a 4 - year - old boy with intestinal obstruction due to Ascaris lumbricoides infestation and discuss its public health significance . - pubmed
The study reviewed the clinicopathological features and outcomes of patients who developed t - MN . - pubmed
METHODS : Retrospective analysis of all patients diagnosed with t - MN by 2016 WHO classification , from a cohort of 521 patients who received PRRT / PRCRT over a 12 - year period . - pubmed
RESULTS : Twenty - five of 521 ( 4.8 % ) patients were diagnosed with t - MN , including six acute myeloid leukaemia ( AML ) and 19 myelodysplastic syndrome ( MDS ) . - pubmed
Twenty - two of 25 ( 88 % ) patients had grade 1 - 2 pancreatic or small bowel NEN with moderate metastatic liver burden . - pubmed
Azacitidine therapy was utilised in ten eligible patients , while four received induction chemotherapy for AML . - pubmed
Sexual transmission by African genotype ZIKVs has not been assessed in laboratory animal models , due to rapid and high mortality rates of immunodeficient mice following inoculation . - pubmed
The African genotype and chimeric ZIKV elicited greater pathogenic effects in the male reproductive tract and generated higher viremias . - pubmed
The extracts revealed also able to inhibit fungal and bacterial species involved in ulcerative colitis , including Candida albicans , Candida tropicalis , Staphylococcus aureus , and Staphylococcus thyphimurium . - pubmed
Finally , we also showed the antiproliferative effects exerted by the EA extracts on human colon cancer HCT116 cell line . - pubmed
The goal of enhanced recovery is to improve patient outcome by improving organ function and decreasing postoperative complications , and therefore decreasing length of hospital stay . - pubmed
Conclusion A model that includes pretreatment fluorine 18 - fluorodeoxyglucose PET texture features from the primary tumor , tumor penumbra , and bone marrow predicts disease - free survival of patients with non - small cell lung cancer more accurately than clinical features alone . - pubmed
OCTA has become an important tool nowadays in the diagnosis and follow - up of patients with age - related macular degeneration , inherited chorioretinal diseases , diabetic retinopathy , retinal vascular occlusive diseases and optic nerve disorders . - pubmed
This mini - review describes the use of OCTA in patients with NIPU and summarizes some practical points in several uveitic entities . - pubmed
Untreated patients in need of systemic therapy with symptomatic and progressive iNHLs including follicular ( FL ) and marginal zone lymphoma ( MZL ) , mucosa - associated lymphoid tissue ( MALT ) , small lymphocytic ( SLL ) , and lymphoplasmacytic ( LPL ) lymphoma were eligible . - pubmed
Two - hundred and fifty patients [ FL 42 % , MZL / MALT 38 % , LPL/ Waldenstrom Macroglobulinaemia ( WM ) 11 % , SLL 9 % ] were enrolled and randomized ( R - CHOP : 127 , R - CVP : 123 ) . - pubmed
Grade III / IV adverse events ( 65 vs. 22 ) occurred in 40 ( 33 1 % ) and 18 ( 15 3 % ) patients , P = 0 001 ; neutropenia in 16 ( 11 6 % ) and 4 ( 3 4 % ) patients , P = 0 017 ; infection in 14 ( 10 7 % ) and 3 ( 2 5 % ) patients , ; P = 0 011 ; and a second neoplasm in three versus seven patients . - pubmed
This multicentre randomized study with > five - year follow - up shows similar outcome in patients with indolent lymphoma in need of systemic therapy treated with R - CVP or R - CHOP immunochemotherapy and rituximab maintenance in both arms . - pubmed
INTRODUCTION : The most suitable treatment in most early - stage lung cancer patients is surgical resection . - pubmed
METHODS : A prospective analysis study with 3,307 patients operated for bronchopulmonary carcinoma in 24 hospitals . - pubmed
After initial radiographs , ultrasound ( US ) is often the next modality utilized to evaluate patients with suspected soft tissue infections given its low cost , availability , portability , and potential for real - time guidance of fluid aspiration . - pubmed
METHODS : A retrospective analysis was performed to identify patients with phyllodes tumors who underwent surgery between 2002 and 2014 using a regional pathology database . - pubmed
Here , we demonstrate that rheumatoid arthritis ( RA ) patients and arthritic mice have a reduction in microbial - derived short - chain fatty acids ( SCFAs ) compared to healthy controls and that in mice , supplementation with the SCFA butyrate reduces arthritis severity . - pubmed
Efficacy and safety of immune checkpoint blockade in self - identified black patients with advanced non - small cell lung cancer . - pubmed
BACKGROUND : To the authors ' knowledge , race - based differences in efficacy for the treatment of patients with advanced non - small cell lung cancer ( NSCLC ) have not been studied to date due to the underrepresentation of patients of minority backgrounds in pivotal trials . - pubmed
METHODS : The authors retrospectively analyzed the clinical outcomes of patients with advanced NSCLC who were treated with single - agent immune checkpoint blockade ( ICB ) between 2013 and July 2018 at Winship Cancer Institute of Emory University in Atlanta , Georgia . - pubmed
The malaria parasite , Plasmodium falciparum , was introduced into Hispaniola and other regions of the Americas through the slave trade spanning the 16th through the 19th centuries . - pubmed
Multimodality imaging in a patient with hydatid disease of the pelvic bone . - pubmed
11 children ( 3.2 % ) required intensive care admission for altered mental status / status epilepticus ( 3 ) , sepsis ( 2 ) and ARDS ( 6 ) . - pubmed
A percentage of patients with PCMs present with trigeminal pain . - pubmed
We present four patients with small PCMs presenting with Trigeminal neuralgia ( TN ) that were treated with radiosurgery and continued to have debilitating trigeminal pain afterwards . - pubmed
METHODS : Patients with petroclival meningiomas presenting with trigeminal pain and having persistent pain after treatment with radiosurgery were included in our review . - pubmed
Those patients were treated with microsurgical resection of their tumor to help control their persistent pain . - pubmed
The primary aim of the review was to assess the patients ' Barrow Neurological Institute ( BNI ) trigeminal neuralgia scores following microsurgical resection . - pubmed
Twenty - six patients with cervical spondylosis and radiculomyelopathy were treated surgically . - pubmed
Mediterranean fruit flies : sterility and sexual competitiveness in the laboratory after treatment with gamma irradiation in air , carbon dioxide , helium , nitrogen or partial vacuum . - pubmed
Four adult female patients with moyamoya vessels are described . - pubmed
Hypertension and hyperlipidaemia were discovered in three patients . - pubmed
This paper reports on 25 patients with MVP in a family practice setting and compares this experience to recent literature on this problem . - pubmed
Thirteeen patients with the characteristic signs and symptoms of the nevoid basal cell carcinoma syndrome ( NBS ) are presented . - pubmed
The jaw cysts removed from the patients with NBS were clinically , radiologically , and histopathologically typical keratocysts with a high occurrence of epithelial islands and/or microcyts in the connective tissue of the capsule . - pubmed
The significantly higher occurrence of proliferative epithelial remnants in the connective tissue of the cyst wall may be an explanation of the high recurrence rate seen in patients with NBS and of the recurrence of some solitary keratocysts in patients without any signs or symptoms of NBS . - pubmed
In a follow - up period of 2 years , 85 % of the patients with NBS showed recurrence . - pubmed
One - third of these patients did not show any recurrence at the 1 - year follow - up . - pubmed
Therefore , a follow - up period of 2 years or more is mandatory in the care of patients with the nevoid basal cell carcinoma syndrome . - pubmed
In vitro and in vivo studies on the mechanism of experimental autoimmune thyroiditis in guinea pigs . - pubmed
Letter : Serological evidence for infection of sheep with Leptospira interrogans serotype hardjo . - pubmed
In the present investigation 100 psoriatic patients were examined for the presence of oral lesions . - pubmed
Tracheobronchial aspirates were obtained from 27 normal horses and from 57 horses with respiratory disease . - pubmed
Eosinophils were rarely found , even from horses with histories suggestive of allergic respiratory disease . - pubmed
Aspirates from horses with epistaxis frequently had macrophages with intracytoplasmic green globules ( hemosiderin ) . - pubmed
Four horses with no clinical signs of lung disease and lungs that were unremarkable on percussion and normal on auscultation had adpirates suggestive of inflammation ; histologic examination confirmed bronchiolitis . - pubmed
Coumarin is an investigational new drug that has produced objective tumor regression in some patients with metastatic renal cell carcinoma and malignant melanoma . - pubmed
Coumarin has shown activity against prostatic carcinoma in the Dunning R-3327 rat prostatic adenocarcinoma model . - pubmed
Coumarin is a relatively nontoxic drug that may warrant further trials in a subset of patients with prostatic carcinoma . - pubmed
Eighteen patients with necrotizing fasciitis of the extremities were reviewed . - pubmed
The subtle size differences between the large aggregating PGs isolated from rat chondrosarcoma , bovine nasal septal cartilage , and adult bovine articular cartilage ( which consists of two subpopulations ) can be distinguished by their migration on these large pore gels . - pubmed
Nine consecutive patients were studied with a presumable diagnosis of pulmonary aspergilloma . - pubmed
Hypothermia and infection in elderly patients admitted to hospital . - pubmed
Twenty - five consecutive elderly patients with hypothermia were studied . - pubmed
An autopsy case of a 70 - year - old woman with sarcoidosis followed up for 16 years is reported . - pubmed
Electrical carotid sinus nerve stimulation was applied in three normotensive anginal patients and one hypertensive patient during upright tilting . - pubmed
Different patterns of glycolipid antigens are expressed following differentiation of TERA-2 human embryonal carcinoma cells induced by retinoic acid , hexamethylene bisacetamide ( HMBA ) or bromodeoxyuridine ( BUdR ) . - pubmed
Haemodynamic and hormonal effects of cilazapril in comparison with propranolol in healthy subjects and in hypertensive patients . - pubmed
Seventeen hypertensive patients received after a 2 week placebo period in random order cilazapril ( 2.5 mg day-1 ) or propranolol ( 120 mg day-1 ) for 3 weeks . - pubmed
The fimbriae of 50 strains of serotype Gallinarum and 35 strains of serotype Pullorum of the genus Salmonella were compared with the type-1 fimbriae of serotype Typhimurium strains by immune electron microscopy and dot blot hybridization tests with gene probes for type-1 fimbriation in Typhimurium . - pubmed
A pancreatic injury may evolve over time so that repetitive clinical diagnostic studies may be required to evaluate the condition of these patients . - pubmed
In seven conscious dogs , endocardial ST - segment changes within the central ischemic area at 2 min after coronary occlusion were compared with the amount of reactive hyperemia and collateral blood flow . - pubmed
We have treated 29 patients with UM ( 9 treated continuously and 20 treated intermittently ): II with PV , 16 with ET , and 2 with myelofibrosis ( MF ) . - pubmed
Three patients developed AL , two after continuous therapy . - pubmed
These two patients with PV had received the fourth highest and highest total dose of UM , and their duration of treatment was the third and fourth longest among the nine patients treated continuously , respectively . - pubmed
One out of 20 patients treated intermittently with UM developed AL . - pubmed
This patient ( 3 ) with ET had received the highest total dose of UM , and her duration of treatment was the longest among the 20 patients treated intermittently . - pubmed
A comparison of the efficacy of high dose and normal dose budesonide in prednisone dependent patients with chronic obstructive lung disease ( COLD ) . - pubmed
Mononuclear as well as polymorphonuclear cell infiltration was seen predominantly in the pars plana region of the ciliary body of test animals with uveitis . - pubmed
Increasing the concentration of glucose from 5 to 10 mM in the perfusion fluid did not alter the function in either control or in diabetic rat hearts . - pubmed
When the study was repeated on hearts from 6 - week diabetic animals , cardiac function of diabetic rats was significantly depressed as compared with controls . - pubmed
on the acquisition of kindled - amygdaloid seizures in the rat was studied . - pubmed
Further studies with additional fully amygdaloid kindled rats failed to show significant modification of suprathreshold or threshold elicited seizures after single 30 - 60 mg / kg i.p . - pubmed
Despite previous studies which have shown antibodies to GM1 ganglioside to be convulsive , no anticonvulsant activity was demonstrated in this study with exogenous GM1 ganglioside using a battery of kindled - amygdaloid seizure tests in the rat . - pubmed
Neural tube closure defects occurred in 33 % of the embryos obtained from matings of male mice heterozygous for a reciprocal chromosome translocation ( T(2;4)1Sn ) with normal female CFLP mice . - pubmed
Two definitive chronic inhalation bioassays on rodents have demonstrated that formaldehyde produces nasal cancer in rats and mice at 14 ppm and in rats at 6 ppm , which is within the domain of present permissible human exposure ( 8 - hr time - weighted average of 3 ppm , a 5 ppm ceiling , and a 10 ppm short - term exposure limit ) . - pubmed
Comparison with the values of PBI in healthy children , in children with hypothyroidism during therapy and in children with tall stature ] . - pubmed
Potentiation of amygdaloid kindling and metrazol - induced seizures by 6 - hydroxydopamine in rats . - pubmed
Pseudomonas aeruginosa cervical diskitis with chondro - osteomyelitis in an intravenous drug abuser . - pubmed
Studies on the mechanism of cytoplasmic antigen accumulation following infection with a new variant of polyoma virus . - pubmed
Although the simultaneous measurement of multiple peptides in patients with benign gastrointestinal disease has yielded information that contributes to our understanding of the complexities of gut neuroendocrine interaction , the pathophysiological role of gut peptides and their clinical relevance need further evaluation . - pubmed
In 38 hyperlipoproteinemic patients , known to be at risk for early CVD , fibrinolytic activity was measured before and after stimulation with DDAVP . - pubmed
Fibrinolytic activity and response to DDAVP were lowest in those patients with hypertriglyceridemia who also had a tendency to develop hyperchylomicronemia . - pubmed
Pattern - reversal retinal potentials ( PRRPs ) are electrical signals generated within the human retina , possibly by the retinal ganglion cells , when a phase - alternating checkerboard pattern ( or grating ) is viewed . - pubmed
At the time of diagnosis by renal biopsy two patients had severe chronic renal failure . - pubmed
STUDY DESIGN : Patients treated with a transpedicular anterior and posterior convex hemiepiphysiodesis and hemiarthrodesis for progressive congenital scoliosis were followed to evaluate this treatment . - pubmed
METHODS : Nineteen curves were fused in 16 patients who had a variety of congenital anomalies . - pubmed
CONCLUSIONS : This procedure appears to be most effective in arresting growth in the young patient who has an isolated hemivertebrae and no excessive kyphosis . - pubmed
The effect of nasal CPAP on nocturnal reflux in patients with aperistaltic esophagus . - pubmed
It has been shown that nasal continuous positive airway pressure ( nasal CPAP ) significantly reduces nocturnal reflux both in patients with sleep apnea and in patients without sleep apnea but consistent abnormal nocturnal reflux . - pubmed
Seven patients with scleroderma esophagus and six patients treated for achalasia were tested over a 48 - h period . - pubmed
The percentage of time the pH & lt ; 4.0 , the number of reflux events & gt ; 5 min , and the length of the longest reflux event were all significantly reduced in the patients with achalasia ( p & lt ; 0.03 ) , but not in the scleroderma group ( p & gt ; 0.20 ) . - pubmed
These results suggest that a residual resting LES pressure greater than that demonstrated by patients with scleroderma ( & gt ; 10 mm Hg ) may be necessary for nasal CPAP to affect nocturnal reflux . - pubmed
Zygomycosis caused by Conidiobolus coronatus in a llama ( Lama glama ) . - pubmed
RESULTS : The mean duration of infection was 3.0 years ( SD 1.9 years ) , and between four and ten courses of antibiotics had been prescribed for six of the 12 patients . - pubmed
Clinical improvement was dramatic in most lesions , and four patients healed completely without recurrence after a total 7 - 10 g of ceftriaxone . - pubmed
Increased risk of Pneumocystis carinii pneumonia in patients with Wegener ' s granulomatosis . - pubmed
During a 10 - month period , we observed 6 cases of Pneumocystis carinii pneumonia ( PCP ) in 23 patients with biopsy - proven WG and renal involvement . - pubmed
Renal function was significantly impaired ( creatininemia = 493.5 vs 195.4 micromol / l ; p = 0.03 ) in the 6 patients presenting PCP vs those without . - pubmed
For these patients , this opportunistic infection must remain highly suspect in order to reach a diagnosis earlier and rapidly initiate treatment . - pubmed
The high levels of LTB4 measured in the bronchoalveolar lavages and pulmonary tissues from nonimmune animals infected with live bacteria implicate LTB4 as an important amplifier of the inflammatory response during acute pulmonary infections with mucoid P. - pubmed
METHODS : Pregnancy outcome was studied in 311 women with class B - RF diabetes from two institutions . - pubmed
Using 104 women without chronic hypertension followed at the University of California , San Francisco , we constructed a receiver - operating characteristic curve relating 24 - hour urinary total protein before 20 weeks ' gestation to the subsequent development of preeclampsia . - pubmed
From the curve , a predictive cutoff level of proteinuria was selected and tested in two validation groups not used to construct the curve : 158 women without chronic hypertension followed at the University of Cincinnati and 49 women with chronic hypertension from both institutions . - pubmed
The Wistar fatty rat is a model of obese non - insulin - dependent diabetes mellitus . - pubmed
On the other hand , female fatty rats develop hyperglycemia only when they are given sucrose for several weeks . - pubmed
The paper presents a patient with acute pancreatitis ( AP ) after partial gastrectomy by means of Billroth mode . - pubmed
METHODS : We analyzed the clinical course of 271 hypertensive patients delivered at a tertiary center . - pubmed
An 11 - month - old boy with Downs Syndrome and obstructive sleep apnoea presented for tonsillectomy . - pubmed
Seven groups ( 2596 subjects ) were vaccinated with a human live anthrax vaccine ( HLAV ) by three different routes ( scarification , subcutaneous and aerosol ) . - pubmed
Rats pituitary - grafted at the 30th day showed a greater hyperprolactinemia than rats grafted at the 5th or 60th day . - pubmed
The case is described of a 58 year old man with systemic Whipple ' s disease with pericardial and pleural effusions and severe pulmonary hypertension . - pubmed
The aim of this work was to evaluate in an immunosuppressed rat cryptosporidiosis model a new method that combines vacuum and low - temperature hydrogen peroxide gas plasma for sterilization of endoscopic material contaminated by Cryptosporidium parvum . - pubmed
Septic thrombus formation of both the main portal vein and its intrahepatic branches were observed on CT in a patient with peripancreatic abscess . - pubmed
The management and clinical course of patients with myasthenia gravis admitted to a neurological intensive therapy unit ( ITU ) for thymectomy over a 66 month period were reviewed . - pubmed
Plasma exchange was required for two patients ( 3.8 % ) due to persistent severe myasthenic weakness . - pubmed
Thymectomy for myasthenia gravis is followed by sustained clinical improvement in the majority of patients . - pubmed
Tamoxifen and toremifene , both used to treat advanced breast cancer , also have beneficial effects on bone mineral density and serum lipids in postmenopausal women . - pubmed
Tamoxifen was recently shown to decrease the risk of invasive breast cancer in women at high risk . - pubmed
Raloxifene , used for prevention of postmenopausal osteoporosis and fragility fractures , also has favourable effects on bone mineral density , serum lipids and the incidence of invasive breast cancer in postmenopausal women but does not stimulate the endometrium . - pubmed
Cortical dysgenesis arising from neuronal migration disorders is closely associated with intractable epilepsy in humans . - pubmed
These results suggest that the excitability of the CA1 region in rats with hippocampal dysplasia is greater than in control animals . - pubmed
Prospective genotyping of schizophrenic patients for the many genes at the level of the drug target , drug metabolism , and disease pathways will contribute to individualized therapy matching the patient 's unique genetic make - up with an optimally effective drug . - pubmed
IAPAC proposes rationing HIV drugs in the U.S. International Association of Physicians in AIDS Care . - pubmed
Risk assessment in patients with acute myocardial infarction treated with thrombolytic therapy . - pubmed
We investigated consecutive patients with AMI treated with thrombolysis to further clarify this issue . - pubmed
RESULTS : A total of 6 patients died , seven had a nonfatal reinfarction , and 23 were revascularized . - pubmed
Patients suffering either death or nonfatal reinfarction had a clinical risk assessment score 2 points higher ( 8.8 vs. 6.7 , P = 0.05 ) than the group without such events . - pubmed
via echocardiography ) contribute with prognostic information in thrombolysed MI - patients . - pubmed
METHODS : Vitreous fluid was taken from patients with PDR ( ET-1 , n = 12 ; NO , n = 12 ) and from patients with macular holes as controls ( ET-1 , n = 10 ; NO , n = 10 ) at vitreous surgery . - pubmed
There was a significant difference between patients with PDR and controls ( P = 0.009 , Mann - Whitney ) . - pubmed
Nitrate ( NO3 ) was 49.8 + /- 5.0 micromol / L in patients with PDR and 24.2 + /- 2.8 micromol / L in patients with macula hole ; it was also significantly elevated in patients with PDR ( P = 0.004 , Mann - Whitney ) , whereas nitrite ( NO2 ) was not detected in this study . - pubmed
When exponentially growing cells , both mouse fibroblasts and human cancer cell lines , were incubated with purvalanol A for prolonged periods of time ( 24 hr ) , a lasting inhibition of cell proliferation as well as cell death were observed . - pubmed
Molecular and morphological studies on the Anopheles minimus group of mosquitoes in southern China : taxonomic review , distribution and malaria vector status . - pubmed
Malignant rhabdoid tumor of the clitoris in an elderly patient : report of a case . - pubmed
We report a case of malignant rhabdoid tumor of the clitoris occurring in an elderly patient . - pubmed
OBJECTIVE : To compare the predictive value of conventional two - dimensional ultrasound measurement of cervical length and three - dimensional multiplanar volume assessment of the cervix for delivery at & lt ; 37 weeks of gestation among patients with preterm labor . - pubmed
MATERIALS AND METHODS : This preliminary prospective study was conducted in 28 patients hospitalized for preterm labor between 24(+0 ) and 33(+6 ) weeks of gestation , defined by regular and painful uterine contractions ( at least two per 10 min ) , intact membranes and a cervical length of & lt ; or = 26 mm measured by two - dimensional transvaginal ultrasonography at admission with a Voluson 530 ( Kretz , France ) machine using a 7.5 - MHz transvaginal transducer . - pubmed
Convulsive threshold values to parenterally injected pentamethylenetetrazole in epileptic monkeys . - pubmed
[ Isoplasm therapy of acute dehydration in children ] . - pubmed
Comparative studies on adrenal cortical function and cortisol metabolism in healthy adults and in patients with shock due to infection . - pubmed
A study of the anemia occurring in the tumor - bearing mice of the C3H strain . - pubmed
The aim of this case - control study was to investigate the relationship between trace elements , immune parameters , and human cancer , taking into account some personality traits , such as anxiety , implicated in the modulation of both immune responses and pathology . - pubmed
Thirty patients affected by the most frequent cancer types were recruited at the onset of disease together with 30 healthy controls . - pubmed
The only differences found between trace element levels in cases and controls were significantly higher erythrocyte Zn in cancer patients and higher plasma Cu levels in male patients . - pubmed
Interestingly , in patients only , GSH - Px in plasma was positively related to trait anxiety scores ( p & lt ; 0.02 ) and Cu to state anxiety scores ( p & lt ; 0.05 ) . - pubmed
Improved glycemic control induces regression of left ventricular mass in patients with type 1 diabetes mellitus . - pubmed
We sought to determine whether improved glycemic control in patients with type 1 diabetes mellitus will induce reversal of those abnormalities . - pubmed
METHODS : We prospectively studied 19 patients ( mean age 40+/-9 years ) with longstanding type 1 diabetes mellitus ( 28+/-4 years ) , who participated in a program of stringent glycemic control . - pubmed
CONCLUSIONS : Improved glycemic control in patients with type 1 diabetes mellitus is associated with regression of septal thickness and left ventricular mass without significant effect on systolic or diastolic function , in the absence of significant alterations in ambulatory 24 - h blood pressures . - pubmed
The authors report two cases of patients presenting with complex voiding disorders treated successfully by bilateral neuromodulation . - pubmed
The incidence of bacteremias due to MRSA and Pseudomonas aeruginosa has remained unchanged ( P & lt;.20 ) ; however , that due to enteric gram - negative bacteria , particularly Klebsiella pneumoniae has increased ( P = .02 ) . - pubmed
Prognostic factors for survival of patients with glioblastoma : recursive partitioning analysis . - pubmed
Survival for patients with glioblastoma multiforme is short , and current treatments provide limited benefit . - pubmed
In this retrospective study of 832 glioblastoma multiforme patients enrolled into prospective clinical trials at the time of initial diagnosis , we evaluated several potential prognostic markers for survival to establish risk groups . - pubmed
The 2 lower risk groups included patients under the age of 40 , the lowest risk group being young patients with tumor in the frontal lobe only . - pubmed
Eighty patients with acute right hemisphere stroke and 81 controls performed the CLBT that consists of two subtests , the Letter - line and Star - line Bisection tasks . - pubmed
This total score detected 55 ( 68.8 % ) patients with neglect . - pubmed
Within this group , the Letter - line and Star - line tasks diagnosed neglect in 50 and 48 patients , respectively , resulting in the highest sensitivities ( 90.9 , 87.3 % ) of the six tests . - pubmed
These data suggested that it is possible to apply them to hemodialyzers , oxygenators and percutaneous glucose sensors to keep diabetic patients easier . - pubmed
INTERPRETATION : High bone mineral content at operation correlates significantly with periprosthetic bone loss after five years in younger patients with cementless custom femoral implant . - pubmed
BACKGROUND : Cardiac resynchronization reduces symptoms and improves left ventricular function in many patients with heart failure due to left ventricular systolic dysfunction and cardiac dyssynchrony . - pubmed
CONCLUSIONS : In patients with heart failure and cardiac dyssynchrony , cardiac resynchronization improves symptoms and the quality of life and reduces complications and the risk of death . - pubmed
The recurrent laryngeal nerves were examined by electron microscopy in five control , four subclinical and four clinical laryngeal hemiplegic horses . - pubmed
This syndrome , first described by Widal in 1922 , is very frequent : it affects nearly 15 % of asthmatic patients and is usually associated with severe and sometimes fatal asthma . - pubmed
An immunopharmacological study of basophil activation ( detected by flow cytometry ) , sulfidoleukotriene production in the presence of NSAIDs in vitro , and other related studies reviewed here have revealed that : a ) basophils from patients with the Widal syndrome are hyperactivated in a non specific manner , probably related to chronic inflammation in the skin or airways ; b ) these hyperactive basophils produce increased amounts of sulfidoleukotrienes but decreased amounts of PGE2 when exposed to NSAIDs in vitro . - pubmed
Rats ' presses on one lever canceled shocks programmed after variable cycles , while presses on a second lever occasionally produced a 2 - min timout during which the shock - delection schedule was suspended and its correlated stimuli removed . - pubmed
Analyses based on the generalized matching law suggest that the reduction in the response requirement correlated with termination of the avoidance schedule was a more important factor in the reinforcing effectiveness of timeout than was shock - frequency reduction , at least in 2 of 3 rats . - pubmed
Ventricular fibrillation during no - flow global ischemia in isolated rabbit hearts . - pubmed
INTRODUCTION : The dominant frequency ( DF ) during ventricular fibrillation ( VF ) in Langendorff - perfused guinea pig hearts is higher in left ventricle ( LV ) than in right ventricle ( RV ) . - pubmed
METHODS AND RESULTS : By using a two - camera optical mapping system , epicardial activation patterns of VF were studied in 12 isolated rabbit hearts during baseline , no - flow global ischemia , and reperfusion . - pubmed
A bimodal extended - release formulation of d - methylphenidate ( d - MPH ) has been developed to enable fast onset of action and once - daily administration in patients with attention deficit hyperactivity disorder . - pubmed
Two hundred twenty thousand children each year acquire folic acid - preventable spina bifida because many governments , including all in Europe , have yet to implement mandatory folic acid fortification . - pubmed
BACKGROUND AND PURPOSE : Priorities in the care of stroke patients are often intuitive . - pubmed
METHODS : The authors retrospectively reviewed the charts of 44 patients who presented to Louisiana State University Health Sciences Center with pelvic plexus tumors . - pubmed
Clinical utility of breast magnetic resonance imaging in patients presenting with primary breast cancer . - pubmed
Since magnetic resonance imaging ( MRI ) of the breast has been shown to be sensitive in identifying the extent of the primary tumor and other foci of cancer , we examined its clinical utility in the surgical management of breast cancer patients . - pubmed
From January 2004 to April 2007 , 117 patients with newly diagnosed breast cancer underwent bilateral MRI prior to definitive surgical management . - pubmed
Six patients ( 5.1 % ) had a larger area of tumor than detected by mammography or ultrasound . - pubmed
Additional foci of cancer were identified in 17 patients ( 14.5 % ): 12 ( 10.2 % ) in the ipsilateral breast and 5 ( 4.3 % ) in the contralateral breast . - pubmed
The main objective of this review is to analyze recent advances and current perspectives in the use of antibiotic delivery systems in the treatment of intracellular infections such as mycobacterial infections , brucellosis , salmonellosis , listeriosis , fungal infections , visceral leishmaniasis , and HIV . - pubmed
RESULTS : Among 151 out of 1935 infected patients 20 were colonized and infected by strains of multidrug - resistant A. - pubmed
In the present study , we investigated a large Pakistani family with 11 affected individuals having hereditary congenital nail clubbing as a single invariable clinical feature without any associated ectodermal , skeletal or systemic imperfection . - pubmed
Toxicity of 3'3 - ditrifluormethyldiphenyl diselenide administered during intra - uterine development of rats . - pubmed
Therefore an earlier diagnosis of MPM is needed to significantly increase the survival of patients . - pubmed
HIV - DNA may be used even in masked primary infection in newborns whose mothers have received HAART . - pubmed
The role of surgery in breast cancer patients with isolated bone metastases at the time of diagnosis . - pubmed
BACKGROUND : Surgery for the primary tumor in breast cancer patients with synchronous isolated bone metastasis is applied for palliation . - pubmed
METHODS : Forty - four patients were diagnosed between the dates June 2004 and January 2007 and these patients are classified according to the removal of the primary tumor or not . - pubmed
Patients and tumor characteristics , removal of the primary tumor , and response to systemic therapy are examined as the factors that were affecting overall survival and time to progression of the disease . - pubmed
CONCLUSION : The response to systemic therapy is the major factor on survival in the breast cancer patients with isolated bone metastasis . - pubmed
Quinone type compound , pulsaquinone 1 , isolated from the aqueous ethanol extract of the roots of Pulsatilla koreana exhibited antimicrobial activities against an anaerobic non - spore - forming gram - positive bacillus , Propionibacterium acnes , which is related with the pathogenesis of the inflamed lesions in a common skin disease , acne vulgaris . - pubmed
This links tobacco smoke as a potential contributing and/or exacerbating factor in exposed individuals with chronic rhinosinusitis . - pubmed
MATERIALS AND METHODS : We reviewed needle biopsy and radical prostatectomy slides from 61 patients in whom cancer was present on transition zone directed needle biopsy . - pubmed
[ Effect of new generation application sorbents on the results of complex treatment in patients with diabetic foot syndrome ] . - pubmed
The work objective is the results of complex treatment improvement in patients with diabetic foot syndrome . - pubmed
The work is based on the results of complex treatment analysis data in 32 patients suffering diabetes mellitus , complicated by diabetic foot syndrome . - pubmed
PATIENTS AND METHODS : Between 1979 and 2008 , 23 infants with MP underwent laparotomy at our institution . - pubmed
Eleven of the 23 infants ( 47.8 % ) developed obstructive jaundice postoperatively . - pubmed
Of these 11 infants , 4 had acholic stools . - pubmed
However , ultrasonography and HIDA scintigraphy should be performed to differentiate BA in infants with MP who show prolonged jaundice with acholic stools . - pubmed
METHODS : A retrospective chart review was performed of 34 consecutive patients over a 5 - year period with NF of the upper and/or lower extremities that required surgical debridement and reconstruction . - pubmed
Laboratory challenges using specific - pathogen - free Pacific herring Clupea pallasii from three distinct populations indicated that stock origin had no effect on susceptibility to viral hemorrhagic septicemia ( VHS ) . - pubmed
Immune tolerance induction in patients with hemophilia A. - pubmed
Characteristics of osteoma of the temporal bone in young adolescents . - pubmed
The author conducted a retrospective review of the clinical presentation , management , and complications of temporal bone osteoma in young adolescents . - pubmed
The study population was made up of 9 patients-5 girls and 4 boys , aged 12 to 15 years at presentation ( mean : 13.7)-who had been seen for radiologically and histopathologically proven temporal bone osteoma at the author 's institution over a 9 - year period . - pubmed
Of this group , 5 patients had extracanalicular osteoma ( 3 in the mastoid portion of the temporal bone , 1 in the squamous portion , and 1 in the mastoid antrum ) and 4 patients had osteoma of the external auditory canal . - pubmed
All patients were followed for a minimum of 1 year , and no recurrences and no complications were observed during that time . - pubmed
Liver transplantation seems ideal for complete resection of bile duct cancer , but the high recurrence rate and decreased patient survival after liver transplant preclude it from being considered standard treatment . - pubmed
All patients were reviewed and examined in 2011 to establish whether the tumour had recurred . - pubmed
One patient had developed a solitary nodular recurrence 8 years after the initial procedure . - pubmed
PURPOSE : Both patients with cutaneous T - cell lymphoma ( CTCL ) and those with atopic dermatitis ( AD ) have pruritus , T(H)2 - biased T cells , and a tendency to have bacterial infections , suggesting a common pathologic basis for these two diseases . - pubmed
EXPERIMENTAL DESIGN : Skin biopsies and sera were collected from patients with CTCL or psoriasis and from healthy volunteers . - pubmed
Gastric mucosa injury model was established by intragastric perfusion of dehydrated alcohol ( 1.0 mL / rat ) . - pubmed
Causes of death of 32 patients on device support included multiple organ failure ( 13 ) , pulmonary failure ( 6 ) , and neurologic injury ( 4 ) . - pubmed
Daphnane diterpene hirsein B downregulates melanogenesis in B16 murine melanoma cells by cAMP pathway inhibition . - pubmed
Therefore , research laboratories and eye clinics using Cirrus HD - OCT as a diagnostic imaging method , can also benefit from a reliable noncontact pachymeter when counseling patients with glaucoma and those undergoing corneal and refractive surgeries . - pubmed
Autoimmune hemolytic anemia in patients with beta - thalassemia major . - pubmed
Hemolysis is a common feature in patients with beta - thalassemia major . - pubmed
Here , the authors described the clinical features and management of 7 patients with beta - thalassemia major and autoimmune hemolytic anemia . - pubmed
These patients had fever , cough , and tea - colored urine on admission . - pubmed
Six of the patients responded well to the management , but 1 patient developed recurrent autoimmune hemolytic anemia that required cyclosporin A treatment . - pubmed
For risk reduction of listeriosis and toxoplasmosis , raw animal foods , soft cheeses and packed fresh salads should be avoided ; fresh fruit , vegetables and salad should be washed well and consumed promptly . - pubmed
In a descriptive and analytic retrospective study we studied the medical records of 63 patients with diffuse large B - cell lymphoma hospitalized during the period from 1991 to 2007 . - pubmed
PEPFAR 's support of TB / HIV integration has also included significant investment in health systems , including improved laboratory services and educating and enlarging the workforce . - pubmed
The scale - up of antiretroviral therapy along with support of programs to increase HIV counseling and testing and improve linkage and retention in HIV care may have considerable impact on TB morbidity and mortality , if used synergistically with isoniazid preventive therapy , intensified case finding , and infection control . - pubmed
Issues to be addressed by future programming include accelerating implementation of isoniazid preventive therapy , increasing access and ensuring appropriate use of new TB diagnostics , supporting early initiation of antiretroviral therapy for HIV - infected TB patients , and strengthening systems to monitor and evaluate program implementation . - pubmed
Patients with AS present a specific set of anesthesia - related challenges , and the parturient with AS presents particular anesthetic considerations . - pubmed
We report our experience with a parturient with advanced AS and offer a novel explanation for the high incidence of epidural failures in this patient population . - pubmed
We have determined the preferences of these phages for Mycobacterium tuberculosis and for other strains of Mycobacterium smegmatis , and find there is a correlation between genome type ( cluster , subcluster , singleton ) and host range . - pubmed
BACKGROUND : Hepatitis B virus ( HBV ) infection is one of the most prevalent viral infections in humans and represents a serious public health problem . - pubmed
The effects of Sutaehwan - Gami on menopausal symptoms induced by ovariectomy in rats . - pubmed
We report here the use of milnacipran , a serotonin and norepinephrine reuptake inhibitor , to treat phantom limb pain after amputation of injured or diseased limbs in three patients . - pubmed
High versus low radioiodine activity in patients with differentiated thyroid cancer : a meta - analysis . - pubmed
BACKGROUND : The purpose of the meta - analysis was to estimate the effectiveness and toxicity of low activity radioiodine ablation versus high activity in patients with differentiated thyroid cancer ( DTC ) . - pubmed
Salivary dysfunction , nausea , and neck pain were significantly more frequent among patients with higher dose for ablation . - pubmed
CONCLUSION : Our meta - analysis provides some evidence from randomized trials that a lower activity of radioiodine ablation is as effective as higher dose after surgery in patients with DTC with lower toxicity . - pubmed
Ominous odors : olfactory control of instinctive fear and aggression in mice . - pubmed
Cysticercosis in humans is caused by Taenia solium larvae infestation . - pubmed
We present a case of masseter cysticercosis in a young woman who presented with painful recurrent cheek swelling . - pubmed
Copper overload in patients with Wilson ' s disease is caused by impairment to the biliary route for excretion of dietary copper A combination of neurological , psychiatric and hepatic symptoms can make the diagnosis of Wilson ' s disease challenging . - pubmed
METHODS : Advanced NSCLC patients with central airway obstruction were enrolled . - pubmed
Eight patients were undergoing additional treatment after resolving airway obstruction . - pubmed
The neurological examination in the assessment of polyneuropathy in mechanically ventilated patients . - pubmed
We wanted to see which clinical parameters can be used to identify patients with polyneuropathy in the intensive care . - pubmed
Health care utilization and access to human immunodeficiency virus ( HIV ) testing and care and treatment services in a rural area with high HIV prevalence , Nyanza Province , Kenya , 2007 . - pubmed
We present health and demographic surveillance system data to assess associations with health care utilization and human immunodeficiency virus ( HIV ) service receipt in a high HIV prevalence area of western Kenya . - pubmed
It is important to include hypothyroidism as the differential diagnosis in patients with cardiac tamponade and altered level of consciousness especially in winter months . - pubmed
The majority ( 72%;1480/2,2060 ) of the participants responded that they would get tested if free testing were offered , and 67 % ( 1272/1912 ) of those responded that they would test for hepatitis B / C in conjunction with HIV . - pubmed
Most individuals would elect to be tested for hepatitis with HIV , which raises the possibility of integrated testing . - pubmed
Increased macromolecular damage due to oxidative stress in the neocortex and hippocampus of WNIN / Ob , a novel rat model of premature aging . - pubmed
This animal model exhibits all traits of metabolic syndrome and has a remarkably reduced lifespan ( 1.5 years as compared to 3 years in parental WNIN rats ) , albeit , the factors associated with premature aging are not well understood . - pubmed
Our study revealed that the magnitude of oxidative stress and DNA damage in the neocortex and hippocampus of 3 - month - old WNIN / Ob obese rats is as high as that seen in 15 - month - old parental WNIN control rats . - pubmed
From these results , it can be concluded that increased oxidative stress - induced damage of macromolecules , probably due to reduced activity of antioxidant enzymes , is associated with premature aging in WNIN / Ob obese rats . - pubmed
OBJECTIVES : This study aimed at identifying the problem areas in GPs ' patient care during the H1N1 and EHEC ( enterohemorrhagic strain of Escherichia coli ) outbreaks . - pubmed
The marrow necrosis , adipocyte hypertrophy and proliferation , diminished hematopoiesis , thinner and sparse trabeculae , and increased empty osteocyte lacunae in the femoral head were observed in Group M and Group Con rabbits . - pubmed
Synergistic in vitro anti - tumor effect of letrozole and everolimus on human endometrial carcinoma Ishikawa cells . - pubmed
OBJECTIVES : To investigate the in vitro effect of the use of combination of letrozole and everolimus on the proliferation and apoptosis of human endometrial carcinoma Ishikawa cells . - pubmed
Bilateral central retinal vein occlusion in a patient with disseminated metastatic renal cell carcinoma treated with sorafenib . - pubmed
PURPOSE : The aim of the article is to report a case of a patient with disseminated metastatic renal cell carcinoma on long - term treatment with sorafenib who had developed bilateral central retinal vein occlusion over a period of 6 months . - pubmed
METHODS : A 73 - year - old man with decreased visual acuity in the right eye and central retinal vein occlusion in the left eye 6 months previously . - pubmed
The patient had been on long - term treatment with the antiangiogenic drug , sorafenib for disseminated metastatic renal cell carcinoma - a highly vascularized tumor . - pubmed
CONCLUSION : The patient with disseminated metastatic renal cell carcinoma on long - term sorafenib treatment should undergo periodic ophthalmologic examinations to exclude any potential vascular complications associated with cancer ( vein occlusion associated with disseminated metastatic disease , tumor embolus , tumor thrombus ) or with treatment ( antiangiogenic drugs , steroids ) . - pubmed
Exploration of skin perfusion in cirrhotic patients with septic shock . - pubmed
BACKGROUND & amp ; AIMS : Skin perfusion alterations are early and strong predictors of death in patients with septic shock . - pubmed
We aimed at assessing whether the mottling score and tissue oxygen saturation ( StO2 ) could be used as early predictors of death in cirrhotic patients with septic shock . - pubmed
METHODS : This observational study included cirrhotic patients with septic shock . - pubmed
Data of 75 non - cirrhotic patients with previously reported septic shock were used as control . - pubmed
Monitoring brain tumor vascular heamodynamic following anti - angiogenic therapy with advanced magnetic resonance imaging in mice . - pubmed
Advanced MR imaging methods have an essential role in classification , grading , follow - up and therapeutic management in patients with brain tumors . - pubmed
In this study , we described clinical profile and outcome of six patients of PSH admitted in neurocritical care unit . - pubmed
All patients admitted at neurology critical unit during 6 - month period from August 2013 to January 2014 were screened for the occurrence of PSH . - pubmed
RESULTS : PSH was observed in 6 patients . - pubmed
The leading causes were traumatic brain injury ( two patients ) , stroke ( two patients ) and Japanese encephalitis ( JE ) ( one patient ) and tuberculous meningitis ( one patient ) . - pubmed
AltitudeOmics : impaired pulmonary gas exchange efficiency and blunted ventilatory acclimatization in humans with patent foramen ovale after 16 days at 5,260 m. A patent foramen ovale ( PFO ) , present in ~40 % of the general population , is a potential source of right - to - left shunt that can impair pulmonary gas exchange efficiency [ i.e. - pubmed
IDX184 is a phosphoramidate prodrug of 2 '- methylguanosine-5 '- monophosphate , developed to treat patients infected with hepatitis C virus . - pubmed
Muscular dystrophy ( MD ) is the most common human genetic disease occurring in approximately 1 in 2500 births . - pubmed
Alternatively , other genes which cause human MD have been genetically disrupted in mice . - pubmed
This paper aims to assess the time - course severity of the disease in the mouse models and determine which is best for MD research . - pubmed
Fate of bone marrow mesenchymal stromal cells following autologous transplantation in a rabbit model of osteonecrosis . - pubmed
In the present study , i - QDs were used to label rabbit mesenchymal stromal cells ( MSCs ) that were then transplanted into rabbits to assess differentiation potential in an osteonecrosis model . - pubmed
[ Clinical study on efficacy of nasal surgical expansion as a basic operation in treatment of patients with OSAHS ] . - pubmed
OBJECTIVE : To observe the clinical effect of nasal surgical expansion as basical surgical treatment of patients with OSAHS . - pubmed
METHOD : A total of 320 patients with OSAHS were retrospectively analyzed . - pubmed
CONCLUSION : Solving the problem of nasal airway obstruction is the first step in surgical treatment of patients with OSAHS . - pubmed
Perioperative VTE occurred in 16 % of cancer patients and was associated with an advanced FIGO stage , but not MV TF PCA . - pubmed
To address this issue , the current study was designed to evaluate the correlation of serum 25 ( OH ) D level and disease activity in patients with UC . - pubmed
METHOD : All consecutively selected UC outpatients referred to a gastroenterology clinic were enrolled in 2014 . - pubmed
RESULTS : Fifty UC patients with mean age of 36.98 ( + - 11.81 ) years were evaluated . - pubmed
CONCLUSION : Lower serum 25 ( OH ) D level might be associated with higher disease activity in UC patients with mild - to - moderate activity . - pubmed
Accordingly , the conventional animal models for AML are mostly myeloablated as leukemia can be induced with short latency and complete penetrance . - pubmed
Recently , a non - irradiated AML mouse model has been established ; therefore , normal hematopoietic cells can be investigated during leukemia development . - pubmed
Experiments based on the non - irradiated animal model have monitored the kinetics of leukemic and ( intact ) hematopoietic cells in multiple tissues simultaneously ; and thus a systematic computational model for the multi - tissue hematopoiesis under leukemia has become possible . - pubmed
Here , we present the first reported case of the course of pregnancy in a woman with the systemic form of Degos disease . - pubmed
Combined beta - glucosylceramide and ambroxol hydrochloride in patients with Gaucher related Parkinson disease : From clinical observations to drug development . - pubmed
RTX patients with at least one episode of CMV viremia tended to have lower GrB+ B - cells as compared to patients without viremic episodes . - pubmed
Polycystic kidney diseases ( PKDs ) are genetic disorders that can cause renal failure and death in children and adults . - pubmed
Case : A 66 year - old woman who presented with sudden lower abdominal pain was transferred to our emergency room . - pubmed
The goal of our current study is to understand the impact of chronological aging on innate immune responses to a secondary , post viral infection with Streptococcus pneumoniae , a causative agent of bacterial pneumonia . - pubmed
MATERIALS AND METHODS : Fifty consecutive pectus excavatum patients , 10 to 32 years of age ( mean age 15 + - 4 years ) , underwent routine cardiac magnetic resonance imaging ( CMR ) including standard measures of chest geometry and cardiac size and function . - pubmed
However , there was significant decrease in mid - cavity circumferential strain magnitude in pectus patients compared with controls ( -11.31 + - 2.79 versus -16.19 + - 2.86 ; p & lt ; 0.001 ) . - pubmed
PE patients had a significantly higher basal circumferential strain ( -13.66 + - 3.09 % versus -9.76 + - 1.79 ; p & lt ; 0.001 ) as well as apical circumferential strain ( -20.73 + - 3.45 % versus -12.07 + - 3.38 ) than control group . - pubmed
CONCLUSION : Mid - cavity circumferential strain but not longitudinal strain is reduced in pectus excavatum patients . - pubmed
CONCLUSIONS : Propamidin - isethionate as diamidine and chlorhexidin as biguanide may be used clinically to reduce cytotoxicity of antiamoebic treatment on human corneal cells . - pubmed
Therefore , in spite of lower cytotoxicity , the inhibitory effect on proliferation and migration indicates that extended use of propamidin - isethionate should be avoided in patients . - pubmed
BACKGROUND : Cysticercosis ( CC ) is a tissue infection caused by the larval cysts of the pork tapeworm Taenia solium . - pubmed
In Brazil , visceral leishmaniasis is caused by the protozoan Leishmania infantum , primarily transmitted by Lutzomyia longipalpis and with the dog as its main urban reservoir . - pubmed
METHODS : Thirty - two Japanese healthy adult rabbits were randomly divided into four groups with 8 rabbits in each group : normal control group ( NC group ) , diabetes mellitus group ( DM group ) , diabetes mellitus + pioglitazone 4 mgxkg-1xd-1 and 8 mgxkg-1xd-1 groups ( DM+PGZ 4 mg and 8 mg groups ) . - pubmed
The use of these medications is rapidly increasing in elderly patients with , and without , dementia . - pubmed
Adjuvant bevacizumab for melanoma patients at high risk of recurrence : survival analysis of the AVAST - M trial . - pubmed
We evaluated the role of adjuvant bevacizumab in melanoma patients at high risk of recurrence . - pubmed
Patients and methods : Patients with resected AJCC stage IIB , IIC and III cutaneous melanoma were randomised to receive either adjuvant bevacizumab ( 7.5 mg / kg i.v . - pubmed
With 6.4 - year median follow - up , 515 ( 38 % ) patients had died [ 254 ( 38 % ) bevacizumab ; 261 ( 39 % ) observation ] ; 707 ( 53 % ) patients had disease recurrence [ 336 ( 50 % ) bevacizumab , 371 ( 55 % ) observation ] . - pubmed
Two patients ( 28.5 % ) had acute kidney injury . - pubmed
Of the 264 children included in the statistical analysis , four were diagnosed with ASD , and four were diagnosed with ODP . - pubmed
New onset psoriasis in a patient with chronic inflammatory demyelinating polyneuropathy treated with Rituximab . - pubmed
A fungus was recovered on potato dextrose agar ( PDA , pH nature ) from the margin of necrotic leaf spots . - pubmed
The development of accelerated methods of detection and differentiation of the virulent properties of pathogenic bacteria will allow scientifically to substantiate and develop a set of measures aimed at preventing animal diseases and obtaining safe livestock products to prevent human diseases . - pubmed
Anthracycline - Induced Cardiotoxicity in Acute Myeloid Leukemia Patients Who Undergo Allogeneic Hematopoietic Stem Cell Transplantation . - pubmed
INTRODUCTION : There is paucity of data regarding the cardiotoxic effects of anthracycline treatment in the context of acute myeloid leukemia ( AML ) patients who undergo allogeneic hematopoietic stem cell transplantation ( HSCT ) . - pubmed
PATIENTS AND METHODS : We reviewed the clinical records and echocardiography examinations of 78 patients with AML who received induction therapy and underwent HSCT . - pubmed
Patients who developed systolic dysfunction had inferior overall survival ( 13 months compared with 27 months ; P = .013 ) . - pubmed
CONCLUSION : Although even transient reduction in systolic function might compromise survival outcome , diastolic dysfunction predicts improved survival in patients with AML who undergo HSCT . - pubmed
Alcohol and HBV synergistically promote hepatic steatosis . - pubmed
Synergy between hepatitis B virus ( HBV ) and alcohol in promoting liver cell damage and disease progression has been reported . - pubmed
However , the interaction of HBV and ethanol in hepatic steatosis development has not been fully elucidated . - pubmed
Furthermore , a meta - analysis of the effects of alcohol and HBV on hepatic steatosis in populations was performed . - pubmed
RESULTS : Hepatic steatosis was significantly more severe in the HBV+EtOH group than in the other groups . - pubmed
In addition , the meta - analysis showed that alcohol consumption increased the risk of hepatic steatosis by 43 % in HBV - infected patients ( pooled risk ratio ( RR)=1.43 , P<0.01 ) . - pubmed
CONCLUSIONS : Alcohol and HBV synergistically promote high - fat diet - induced hepatic steatosis in mice . - pubmed
RESULTS : Altogether 2 127 patients underwent surgery for morbid obesity , whereof 1 468 were women . - pubmed
Obesity - related sequelae were registered in 1 196 patients before surgery . - pubmed
A large proportion of the patients who underwent surgery had obesity - related sequalae . - pubmed
Background : Correcting false cognitions and establishing preventive behaviors in patients with chronic low - back pain can improve self - efficacy and self - discovery of these patients against the physical and psychological consequences of chronic back pain through reinforcing thoughts and constructive behaviors . - pubmed
Effect of Pars Plana Vitrectomy With or Without Cataract Surgery in Patients with Diabetes : A Systematic Review and Meta - Analysis . - pubmed
Given the high rate of accelerated cataract progression after PPV , PPV combined with cataract surgery appears to be an attractive treatment option for patients with diabetes . - pubmed
In four of these studies , final visual acuity did not vary significantly between patients undergoing PPV alone and those undergoing PPV combined with cataract surgery ( combined surgery ) . - pubmed
In addition , patients receiving PPV alone had a lower risk of neovascular glaucoma ( OR 0.36 ; P & lt ; 0.05 ) , iris synechias to anterior capsule ( OR 0.36 ; P & lt ; 0.05 ) , and iris rubeosis ( OR 0.26 ; P & lt ; 0.05 ) compared with those receiving combined surgery . - pubmed
Given the high rates of cataract progression after PPV , combined surgery may be the more appropriate treatment for patients with diabetes and coexistent visually significant cataract . - pubmed
However , the currently adopted methods of modification of T cells pose a risk of insertional oncogenesis because lentiviral and retroviral vectors integrate the CAR transgene in a semi - random fashion . - pubmed
Measurement of the somatic cell count ( SCC ) in milk is commonly used to detect mastitis in lactating dairy cows . - pubmed
Many techniques and tools have been developed and adapted to quantify milk SCC , but few tools have been evaluated in their ability to enumerate somatic cells in non - lactating bovine mammary secretions . - pubmed
The objective of these studies was to evaluate methods of somatic cell quantification , originally developed for milk , in their ability to quantify the SCC in non - lactating bovine mammary secretions when compared to the gold standard microscopic quantification method . - pubmed
Development of a standardized approach for quantifying somatic cells in non - lactating dairy animals such as heifers and cows , via a rapid automated counter , can allow for the detection of mastitis in non - lactating dairy animals . - pubmed
Diagnosis and management of postlaparotomy wound infection caused by Mycobacterium fortuitum . - pubmed
Mycobacterium fortuitum is ubiquitous in nature and can cause a wide variety of lesions in humans with immunocompromised or antecedent chronic illness . - pubmed
Inaccurate point - of - care blood glucose measurement in a dog with secondary erythrocytosis . - pubmed
KEY FINDINGS : A 1.5 - year - old dog , previously diagnosed with multiple congenital cardiac malformations , right - to - left cardiac shunting and secondary erythrocytosis , presented to a veterinary emergency center minimally responsive and without detectable pulses . - pubmed
A pathological cause for hypoglycemia was not identified and PBGM readings were determined to be erroneously low due to the dog 's abnormally high HCT . - pubmed
SIGNIFICANCE : This case demonstrates the limitations of using PBGMs to assess blood glucose in a dog with secondary erythrocytosis . - pubmed
The report emphasizes the need for judicious use of PBGMs in critically ill patients and that these glucometers may not be reliable in patients with abnormal HCT values . - pubmed
METHODS : A case - control study was performed from April 2011 to February 2016 with pregnant women with GDM who needed complementary treatments besides diet and physical exercise . - pubmed
Removal of tumor thrombus from the azygos vein in an esophageal squamous cell carcinoma patient . - pubmed
Neoadjuvant chemotherapy can decrease the stage in patients with advanced preoperative tumor staging , regaining surgical opportunities and significantly prolonging progression - free survival and overall survival . - pubmed
Herein , we present a case of esophageal squamous cell carcinoma accompanied by tumor thrombus in the arch of the azygos vein , and the patient underwent radical surgery after neoadjuvant chemotherapy . - pubmed
CASE PRESENTATION : A 63 - year - old male with esophageal squamous cell carcinoma was found to have tumor thrombus formation in the arch of the azygos vein . - pubmed
In this review , we discuss new advances in pharmacological treatment both in cardiovascular prevention and in HF management with a special focus on T2DM patients . - pubmed
Moreover , SGLT2i demonstrated strong evidence of benefit particularly in HF management both in diabetic and non - diabetic patients . - pubmed
New therapies , which are on the horizon , promise to further reduce cardiovascular mortality and morbidity in HF patients irrespective of diabetic status . - pubmed
In women age 45 to 49 years , 61 ( 96.8 % ) had benign follow - up , one ( 1.6 % ) had atypical hyperplasia , and one ( 1.6 % ) had malignant follow - up . - pubmed
METHODS : This is a case - series of five COVID-19 positive patients who demonstrated severe hypoxemia , declining respiratory performance , and escalating oxygen requirements . - pubmed
Patients met the following criteria : COVID-19 positivity , worsening respiratory performance , severe hypoxemia ( PaO2 < = 80 ) despite traditional supportive measures , escalating supplemental oxygen requirements , and D - dimer greater than 1.5 mug / mL. - pubmed
Patient one was on maximum ventilator support , paralytics , and prone positioning without improvement . - pubmed
Three of these patients avoided intubation due to COVID-19 - associated respiratory failure . - pubmed
Furthermore , the expressions of genes involved in two heart disease - related pathways were down - regulated at the death stage of D. - pubmed
magna after TCEP exposure for 62 days , suggesting that TCEP delayed the death of D. - pubmed
METHODS : Forty - one adults with ID of both sexes , ranging in age from 20 to 60 years old , participated in the study . - pubmed
An 80 - year - old woman presented with abdominal and right lower limb pain . - pubmed
Fifteen healthy controls ( HC ) , 26 cognitively normal PD ( PD - CN ) , and 27 PD - MCI subjects participated in this study . - pubmed
The in vivo gastroprotective effects of that fraction were evaluated using alcohol - induced gastric ulcers in rats . - pubmed
Therefore , we recommend the use of Murcott mandarin leaves as a part of a protection strategy for gastric ulcer . - pubmed
METHODOLOGY / PRINCIPAL FINDINGS : In this study , extracts of fifteen traditional medicines used for treating various NTDs in local communities were screened in vitro for efficacy against schistosomiasis , onchocerciasis and African trypanosomiasis . - pubmed
Here , we use a combinatorial approach on a characterized mouse model of hormone induced male infertility to uncover misregulated pathways . - pubmed
Results suggest that infertility is associated with substantial loss of proteomic heterogeneity , which define distinct stages of seminiferous tubuli in healthy animals . - pubmed
To achieve the optimum survival rate in aortic aneurysms , knowledge of natural course , genetic association , and surgical results are needed to be applied with adequate medical treatment and careful selection of patients for operation . - pubmed
TAA expands up to 0.3 cm annually in a non - bicuspid aortic valve patient . - pubmed
CONCLUSION : In the future , genetic testing may be the gold standard for tackling the geneticheterogeneity of aneurysms , therefore , identifying at - risk individuals developing TAA andAAA earlier . - pubmed
Solid tumor models for the assessment of different treatment modalities : II : rapid , intermediate , and slow growing transplantable rat hepatomas . - pubmed
A double - blind multicenter trial was carried out in 146 patients with urinary tract infections in order to compare the combination of rifampicin and trimethoprim ( 450 mg plus 120 mg twice daily ) with rifampicin alone ( 450 mg twice daily ) . - pubmed
The study reports also four cases of hepatic vein thrombosis ( Budd - Chiari - Syndrome -- Venoocclusive disease ) and three cases of benign hepatic tumors ( liver cell adenoma and focal nodular hyperplasia ) in young women following 2- to 5 - year treatment with oral contraceptive steroids . - pubmed
The rate of excretion of labelled hycanthone has been determined in bile and urine from three strains of rats ( Sprague - Dawley , hooded and Gunn ) , and from dogs , cats , rabbits and monkeys . - pubmed
Genetic variability within and between outbred Wistar strains of rats . - pubmed
The ventriculograms of patients with chronic postinfarction aneurysm of the heart were studied with the use of separate analysis of the contraction indices of the functioning and non - functioning parts of the left ventricular myocardium . - pubmed
A radiological study of 110 patients with special reference to demonstration of cerebral plaques . - pubmed
The brains of 110 patients with multiple sclerosis ( MS ) were examined by computer tomography ( CT ) with the fine matrix EMI scanner . - pubmed
No difference was demonstrated between duration of disease or age at onset in plaque cases , atrophy cases and patients with normal EMI scans . - pubmed
Congenital malformations were registered in 410 pigs equalizing 1.4 per cent of the pigs born ( Table I ) . - pubmed
Patients resistant to the full hypotensive effects of sodium nitroprusside , or unable to maintain the level of hypotension , or requiring more than 3.5 mg per Kg to achieve the required effect for the anticipated time , may accumulate toxic levels of cyanide in the blood . - pubmed
Patients with Leber ' s optic atrophy , tobacco amblyopia and possibly those with other nerve atrophies should not receive sodium nitroprusside or any other cyanide precursor . - pubmed
36 rats and 99 mice survived the terms of appearance of the first tumors . - pubmed
In the experiments on rats sarcomas were found in 9 cases at the site of the injection of the substance . - pubmed
In one rat renal adenocarcinoma developed . - pubmed
Very low values were obtained in patients suffering from malignant disease , especially carcinoma of the prostate . - pubmed
Ultrasonography was performed in 39 patients and detected gallstones in 7 patients and sludge in 3 . - pubmed
Liver biopsies were obtained in 31 patients and cirrhosis was found in 4 . - pubmed
The nucleation time ( median : 21 days ) was higher in patients with chronic pancreatitis than in patients with cholesterol stones ( median : 2 days ) ( P & lt ; 0.001 ) but was not different from nucleation time in patients either free of stones ( median : 21 days ) or with pigment stones ( median : 21 days ) . - pubmed
The cholesterol saturation index was similar in patients with chronic pancreatitis and in controls . - pubmed
The 2 patients with chronic pancreatitis who underwent cholecystectomy had pigment stones . - pubmed
Reduced attention - related negative potentials in schizophrenic children . - pubmed
ERPs were recorded from normal and schizophrenic children during performance of a reaction time task ( RT ) followed by a complex visual discrimination , the span of apprehension task ( Span ) , sensitive to vulnerability factors in schizophrenia . - pubmed
When RT and Span task ERPs are compared , schizophrenic children produced a significantly smaller than normal increment in endogenous negative activity . - pubmed
Angiosarcoma is a well known complication following radiotherapy and lymphedema , and is likely to be seen more frequently as conservation treatment is used more commonly for patients with early breast cancer . - pubmed
Authors discuss nephrotoxicity of aminoglycosides in patients with hepatic and biliary disorders . - pubmed
Various chemicals were tested in Escherichia coli for the ability to modify the cellular growth rate and to induce the synthesis of heat shock and stress proteins . - pubmed
In patients with previously documented or probable sustained ventricular tachycardia , it would seem to be necessary to continue ventricular stimulation irrespective to the rate and duration of the induced non - sustained ventricular tachycardia . - pubmed
A total of 274 patients ( mean age 67.1 + /- 8.2 years ) with asymptomatic stenosis of the internal carotid artery greater than 70 % was treated by desobliteration and patchplasty ; 332 reconstructions were performed either uni- or bilaterally . - pubmed
The author has summed up his experience in the diagnosis and radiation therapy of 6 patients with breast cancer ( 5 ) and lung cancer metastases to the vascular coat of the eye . - pubmed
In 3 patients metastases to the eye developed against a background of tumor generalization . - pubmed
Prolonged follow - up identified relapses in patients assumed to have been cured . - pubmed
Clinical utility of liver biopsy in patients with serum antibodies to the human immunodeficiency virus . - pubmed
For example , 70 % of patients with AIDS , as compared to 25 % of patients with serum antibodies to HIV but without AIDS , had diagnostic liver biopsies . - pubmed
The microbiological etiology of pneumonia in 34 renal transplant patients with clinical and X - ray evidence of pulmonary parenchymal disease was studied . - pubmed
Laboratory evaluation included histological and cytological methods , cultures for bacteria , fungus and virus and immunofluorescence techniques for the detection of Pneumocystis carinii , cytomegalovirus ( CMV ) and legionella . - pubmed
Pulmonary edema was found in 7 patients , bacterial pneumonia in 11 patients , P. - pubmed
Bronchoscopy gave correct diagnosis in 13/14 patients with infectious pulmonary diseases ( 93 % ) . - pubmed
Favourable clinical effects of the antibiotic needle jet injection were observed in the patients with acute nonspecific pulmonary diseases : decreased hospitalization terms and lower total course doses of the antibiotics . - pubmed
[ Effect of isoproterenol on regional myocardial oxygen balance in dog hearts with coronary stenosis ] . - pubmed
Effects of intravenous and intracoronary isoproterenol on oxygen balance in the regional myocardium as well as on coronary hemodynamics were investigated in eight dogs with coronary stenosis under droperidol - fentanyl anesthesia . - pubmed
Managing critically ill patients with esmolol . - pubmed
Cross sectional osteon diameter ( D ) and Haversian canal diameter ( d ) were measured in undecalcified , unstained sections from the mid - diaphysis of femoral bones from 13 patients with long lasting chronic pulmonary insufficiency , 10 patients with unilateral thrombosis of the femoral artery and from sex- and age - matched normal controls . - pubmed
[ No correlation between suppressor cell function and disease activity in natural history studies of patients with systemic lupus erythematosus ] . - pubmed
In ten patients with systemic lupus erythematosus lymphocyte suppressor cell function was repeatedly monitored over a period of nine months . - pubmed
Increased arterial wall stiffness and thickness in medium - sized arteries in patients with insulin - dependent diabetes mellitus . - pubmed
A patient with a giant aneurysm arising from the tonsillomedullary segment of the posterior inferior cerebellar artery ( PICA ) presented with clinical and computed tomography findings suggestive of spontaneous cerebellar hemorrhage . - pubmed
The apparent reversal of a wasting syndrome by nutritional intervention in Saguinus mystax . - pubmed
Within 1 year after arrival , the mortality was 60 % and the majority of the tamarins showed signs similar to " wasting marmoset syndrome " ( WMS ) . - pubmed
Under analysis were clinical data and roentgencardiometric parameters in 181 patients with mitral diseases . - pubmed
Experiments on mice with Ehrlich solid carcinoma showed the dependence of a rise of the antitumor effect of preceding radiation induced by glucose and glucose combined with mexamine on a degree of the blood flow inhibition under the influence of these modifying agents . - pubmed
These results imply that although histamine can modulate immune responses in uninfected animals , it is not a major component of the immunoregulatory pathway induced by infection with N. - pubmed
Twenty - one patients with bladder tumors were treated with THP instillation into the bladder . - pubmed
Of 21 patients , 4 showed complete disappearance of the bladder tumors , while partial response ( 50 % tumor reduction ) was observed in 6 cases . - pubmed
The main side effect of THP instillation was temporary bladder irritability , which was seen in 57 % of all the patients . - pubmed
Ventricular fibrillation was found in 13 of the 20 patients attended by the cardiac arrest team . - pubmed
Effect of a synthetic peptide , ORG 2766 , on inpatients with severe senile dementia . - pubmed
Fenoprofen calcium 600 mg , four times daily , and ibuprofen 400 mg , four times daily , were compared in a double - blind crossover study involving the treatment of soft - tissue rheumatism in fifty patients . - pubmed
The effect of chronic administration of bromocriptine to 20 patients with the polycystic ovary syndrome ( PCOS ) was studied . - pubmed
Eleven out of 20 patients ultimately noted a subjective improvement in hirsutism . - pubmed
Sex differences in the susceptibility of rats to carbon tetrachloride -- alcohol - induced liver injury . - pubmed
However , we have found that continuous administration of very low amounts of amphetamine reliably produces SB in rats , and that this behavioral change can be very selective . - pubmed
We compared SB produced by continuous amphetamine to SB produced by daily caffeine ; the latter has been proposed as an animal model for self - injurious behavior ( SIB ) in the Lesch - Nyhan syndrome . - pubmed
The dopamine antagonist haloperidol was only marginally effective in controlling SB produced by daily caffeine but the dopamine antagonist pimozide ( which has a longer duration of action ) prevented SB by amphetamine pellet rats . - pubmed
Continuous release amphetamine pellets may provide an alternative to the caffeine model of SIB in humans , particularly for the Lesch - Nyhan syndrome . - pubmed
A simple transillumination screening test for identifying patients in whom mydriasis presents a risk is described . - pubmed
The case report presented herein describes a forty - six year old woman with multiple myeloma and cutis laxa . - pubmed
Two of those three had parapneumonic effusions and the remaining one had a tuberculous pleurisy with a previous bacterial empyema . - pubmed
We have compared the effects of nebulized adrenaline and a selective beta 2 agonist ( salbutamol ) on the arterial oxygen saturation ( SaO2 ) , minute ventilation ( VE ) , forced expiratory volume in 1 s ( FEV1 ) , plasma potassium and the electrocardiogram ( ECG ) in patients with chronic stable asthma . - pubmed
There was an increased heart rate after both adrenaline and salbutamol and ventricular ectopic beats and a short run of parasystole were recorded on the ECG in one patient after adrenaline and in two patients after salbutamol . - pubmed
We conclude that both adrenaline and a selective beta 2 agonist salbutamol can cause a fall in SaO2 and ventricular ectopy in some asthmatic patients . - pubmed
All groups , including control , had dogs which had a chronic inflammatory response in the epidural space , as represented by fibrosis , foreign body giant cells , and lymphocytes , but no spinal cord pathology . - pubmed
Plasmids in several strains of Deinococcus radiodurans . - pubmed
A total of 43 patients with advanced , previously untreated non - small - cell lung cancer ( NSCLC ) were treated with a novel nitrosourea , fotemustine , given at 100 mg / m2 on days 1 and 8 . - pubmed
A 62 year old man with chronic lymphocytic leukaemia presented with malabsorption , the cause of which could not be found during life . - pubmed
Physical characterization of plasmid pMQV10 from a steroid biotransforming strain of Micrococcus . - pubmed
The presence of a single plasmid 8.5 kb in size has been demonstrated in a cholesterol biotransforming strain of Micrococcus . - pubmed
From 1973 to 1987 , 28 patients seen at our institution sustained isolated posterior cruciate ligament tears . - pubmed
Entomological studies on prevalence of adult and immatures of Aedes aegypti along with associated ecological factors have been conducted in a dengue endemic area of Jalore , Rajasthan from 1992 to 1993 . - pubmed
Neutralization of the toxic effects of scorpion stings by serotherapy is limited due to the various serotypes expressed by these proteins . - pubmed
HCV viremia levels were not associated with the severity of liver histology , duration of disease or the source of hepatitis . - pubmed
Cell cycle gene regulation in reversibly differentiated new human hepatoma cell lines . - pubmed
Several novel differentiated cell lines have been derived from a human hepatocarcinoma named HBG . - pubmed
Ovine lentivirus ( OvLV ) , a retrovirus , causes lymphoid interstitial pneumonia ( LIP ) in sheep . - pubmed
OBJECTIVE : To better understand the neuropathological correlates of Tourette ' s syndrome ( TS ) , measures of saccadic eye movement performance were examined among patients with TS . - pubmed
Twenty one patients with DSM - IV TS ( mean age 40.6 years ( SD 11.0 ) ; 38 % female ) mainly recruited from UCSD Psychiatry Services , and a community based sample of 21 normal subjects ( mean age 34.6 years ( SD 13.4 ) ; 43 % women ) participated in this study . - pubmed
Whereas patients with TS generated prosaccades with normal reaction times and amplitudes , their saccade durations were shorter and their mean velocities were higher than in normal subjects . - pubmed
During a prosaccade gap task , patients with TS exhibited an increased proportion of anticipatory saccades ( RTs<90 ) . - pubmed
Patients with TS had fewer correct antisaccade responses than did normal subjects , an effect accounted for by 19 % of the patients . - pubmed
Antisaccade reaction times among patients with TS were increased during an overlap version of the task . - pubmed
Nifedipine - induced gingival hyperplasia : non - surgical management of a patient . - pubmed
A clinical report of nifedipine - induced gingivitis in a medically compromised patient is presented . - pubmed
METHODS : From November 1979 to December 1996 , 50 patients with chronic persistent empyema were treated by pedicled omentum majus transplanted into the thoracic cavity . - pubmed
[ The sensitivity of clinical isolates of Helicobacter pylori and associated microflora to antimicrobial and anti - ulcer preparations ] . - pubmed
Combining electrocardiography and necrosis biomarkers improved detection of acute myocardial infarction in patients with LBBB . - pubmed
The establishment and maintenance of effective urinary tract drainage for patients with malignant extrinsic ureteric obstruction is a formidable challenge for the urologist . - pubmed
Lake whitefish ( Coregonus clupeaformis ) were fed diets at a ration of 0.5 % of body weight three times a week containing 0 , 10 , 100 , and 1000 microg Ni / g ( as NiSO ( 4 ) ) for 10 , 31 , and 104 days . - pubmed
OBJECTIVE : The determination of high risk patients for sudden death and sustained ventricular tachycardia after acute myocardial infarction constitutes the main goal to decrease morbidity and mortality . - pubmed
METHODS : Thirty - five patients ( mean age 53 + /- 9 years ) with acute myocardial infarction who were not given thrombolytic therapy were enrolled . - pubmed
Decreased catecholamine - induced cell death in B lymphocytes from patients with rheumatoid arthritis . - pubmed
MATERIAL : From 1989 trough 1999 , 14 young patients , 11 male and three female ranging in age between 13 and 24 years were treated for primary TPPC in our department . - pubmed
Growth retardation and skin abnormalities of the Recql4 - deficient mouse . - pubmed
[ Experimental study of seven strains of lymphocytic choriomeningitis virus of the Armstrong type isolated in man ] . - pubmed
Comparison of some physical and chemical properties of eight strains of tobacco mosaic virus . - pubmed
[ Hypervolemia and hypersalemia in cyanotic children with congenital heart defects ] . - pubmed
Hyperaemia of the deeper cutaneous vessels after irradiation of human skin with large doses of ultra - violet and visible light . - pubmed
Candida tropicalis ATCC 20336 can grow on fatty acids or alkanes as its sole source of carbon and energy , but strains blocked in beta - oxidation convert these substrates to long - chain alpha , omega - dicarboxylic acids ( diacids ) , compounds of potential commercial value ( Picataggio et al . - pubmed
This in vitro study investigated the potential of the heat - treated porcine trabecular bone block as a bone substitute for the treatment of bone defects or related diseases . - pubmed
Down syndrome ( DS ) is the congenital birth defect responsible for the greatest number of individuals with mental retardation . - pubmed
The control of infectious diseases transmitted from animals to humans ( zoonoses ) was recently put on a new basis in the European Union when a new Zoonoses Directive entered into force . - pubmed
Brucellosis , campylobacteriosis , echinococcosis , listeriosis , salmonellosis , trichinosis , and the respective causative agents , tuberculosis due to Mycobacterium bovis , and verotoxigenic Escherichia coli must be included in monitoring . - pubmed
Operative findings and outcomes of microvascular decompression for trigeminal neuralgia in 35 patients affected by multiple sclerosis . - pubmed
Magnetic resonance imaging preoperative identification of suspicious vessels along the cisternal course of the trigeminal nerve in MS patients raises the question of a possible causative role of vascular compression in MS patients . - pubmed
RESULTS : Magnetic resonance imaging revealed the presence of demyelinating lesions affecting the brainstem trigeminal pathways of the painful side in 26 ( 74 % ) of 35 patients . - pubmed
During surgery , severe neurovascular compression at the trigeminal root entry zone was found in 16 ( 46 % ) of 35 patients . - pubmed
There was no mortality , with a 2.5 % long - term morbidity rate ( facial nerve palsy in one patient ) . - pubmed
PARTICIPANTS : 1334 patients consulting their general practices about low back pain . - pubmed
Intratumoral injection of IL - secreting syngeneic / allogeneic fibroblasts transfected with DNA from breast cancer cells prolongs the survival of mice with intracerebral breast cancer . - pubmed
Here , the immunotherapeutic properties of a vaccine prepared by transfection of mouse fibroblasts with DNA from a breast carcinoma ( SB-5b ) that arose spontaneously in a C3H / He mouse ( H-2Kb ) were tested in mice with intracerebral breast cancer . - pubmed
The results of two independent in vitro cytotoxicity assays indicate that systemic cellular antitumor immunity was generated in mice injected i.c . - pubmed
MATERIAL AND METHODS : Fifteen SCL patients suffering from NDO and incontinence were included in the study . - pubmed
CONCLUSION : BTA proved to be a highly effective treatment modality for NDO and incontinence in SCL patients . - pubmed
Caspofungin , an antifungal agent that is a member of the echinocandin family , an inhibitor of glucan synthesis in the fungal wall , is active against Aspergillus and Candidae infections . - pubmed
CASE SUMMARY : This report describes a case of invasive Aspergillus sinusitis in a kidney transplant recipient with diabetes mellitus . - pubmed
The AmBisome had to be discontinued due to deterioration of renal and hepatic function , but the patient completed a further 7 - week course of caspofungin alone . - pubmed
CONCLUSION : This case indicates that caspofungin is effective to treat invasive Aspergillus sinusitis in kidney transplant recipients . - pubmed
BACKGROUND : Noroviruses are common pathogens in gastro - enteritis outbreaks in humans worldwide . - pubmed
CONCLUSIONS : In Hungary , emerging recombinant noroviruses became the second most common norovirus variants - next to GGII-4 / Lordsdale virus - causing epidemics of gastroenteritis in the last 4 years . - pubmed
Successful rapid discontinuation of immunosuppressive therapy at molecular relapse after allogeneic bone marrow transplantation in a pediatric patient with myelodysplastic syndrome . - pubmed
The success of allogeneic bone marrow transplantation ( allo - BMT ) in children with myelodysplastic syndrome ( MDS ) is mainly affected by relapse . - pubmed
The role of additional immunotherapy for pediatric patients with MDS relapsing after allo - BMT remains to be established . - pubmed
Because immunotherapy is generally more effective for patients who bear a low tumor burden , monitoring of minimal residual diseases ( MRD ) is essential for early diagnosis at molecular relapse . - pubmed
NICU patients are at particularly high risk of harm and even death from medical error . - pubmed
METHODS : A human squamous cell carcinoma line ( KB ) , two human osteosarcoma cell lines from mandible ( HOSM-1 , HOSM-2 ) , and the human gingiva - derived fibroblast line ( HF ) , representing normal cells , were used . - pubmed
The macro and microscopical characteristics of hepatic lesions , together with the finding of F. - pubmed
Currently , infliximab is the drug of choice for the treatment of patients with active AS associated with IBD . - pubmed
Early voluntary exercise does not promote healing in a rat model of Achilles tendon injury . - pubmed
We observed the persistent presence of neutrophils in injured tendons of rats that began exercise immediately after the trauma [ injured + early exercise ( Inj+EEx ) ] . - pubmed
Aging individuals with HIV may be at risk for developing more age - related cognitive decline , mild cognitive impairment , or even dementia . - pubmed
OBJECTIVE : To compare growth , lipids and adipocytokines in HIV - positive children with and without lipoatrophy . - pubmed
PATIENTS : Eleven HIV - positive children with facial lipoatrophy , and 22 age- and sex - matched HIV - positive controls without signs of fat abnormality . - pubmed
Strikingly , despite similar BMI z - scores and virological control , lipoatrophic patients were shorter by 1 standard deviation score ( p = 0.03 ) . - pubmed
CONCLUSIONS : The presence of facial lipoatrophy in a child with HIV infection is a marker for significant metabolic derangements including dyslipidemia and hypoadiponectinemia , and suggests the need for careful growth evaluation . - pubmed
Rabies was diagnosed in a 40 kg pig from a closed feeder barn in which recently unexplained deaths of eight to ten pigs had occurred . - pubmed
Managing risk when considering the use of atypical antipsychotics for elderly patients with dementia - related psychosis . - pubmed
In 2005 , responding to several studies , the FDA issued a black box warning on atypical ( second generation ) antipsychotic medications , noting that the drugs may increase the risk of cerebrovascular adverse events in elderly patients with dementia - related behavior disturbances . - pubmed
Oxcarbazepine is an antiepileptic drug that has been approved by the US FDA and is indicated for use as monotherapy or adjunctive therapy in the treatment of partial seizures in adults and children aged over 4 years . - pubmed
In light of controlled and open - label prospective studies , it may be useful for manic symptoms in the treatment of bipolar and schizoaffective patients . - pubmed
In addition , owing to its lower propensity for drug interactions and side effects , it may be useful in the treatment of refractory patients with bipolar and schizoaffective disorder . - pubmed
Subjective satisfaction of the patients was evaluated on the basis of a questionnaire , in which hand function , pain and cosmetic appearance were recorded . - pubmed
Long - lasting pain relief was reported by 79 % and satisfaction with hand function by 90 % of the patients . - pubmed
Improvements in the range of motion and joint alignment and alleviation of pain result in a markedly improved hand function and patients ' satisfaction . - pubmed
A woman with psoriasis vulgaris and psoriatic arthritis developed granulomatous rosacea after four weeks of therapy with etanercept . - pubmed
METHODS : Twenty - four primary FSGS patients were transplanted at our centre from 1997 to 2007 . - pubmed
The 15 ATIP patients using hematopoietic stem cell transplantation ( HSCT ) under minimum nonmyeloablative conditioning was performed using living donors . - pubmed
RESULTS : Mean serum creatinine ( SCr ) values of the 12 ATIP patients who were doing well at 1 , 3 , 5 years and at present were : 1.62 , 1.48 , 1.6 , and 1.92 mg% , respectively , on cyclosporine ( 1.5 + /- 1 mg / kg per day ) and prednisone ( 7.5 mg / day ) . - pubmed
Four patients displayed recurrences at 8 days , 1 month , and 1 and 2 years posttransplant . - pubmed
One patient died at 1 year posttransplant ; one patient received a subsequent cadaver donor graft and two are on maintenance dialysis . - pubmed
[ Changes of blood pressure and pulse rate and the microstructure of celiac ganglion in rabbits with damaged celiac ganglion induced by high intensity focused ultrasound and alcohol ] . - pubmed
CURRENT GUIDELINES : At present , appropriate treatment for girls with TS may include growth - promoting therapy and pubertal induction with the dual aims of optimizing adult height and facilitating psychosocial adjustment . - pubmed
Olanzapine compared to quetiapine in adolescents with a first psychotic episode . - pubmed
OBJECTIVE : To compare the efficacy , safety , and tolerability of olanzapine and quetiapine in adolescents with first episode psychosis . - pubmed
METHOD : Fifty adolescents ( age 16 + /- 1.25 ) with a first episode of psychosis were randomized to quetiapine or olanzapine in a 6 - month open label study . - pubmed
We have investigated the in vitro antitumor activity of the mushroom Agaricus blazei Murill on human cancer cell lines as well as its potential anticancer activity in a model of rat colon carcinogenesis . - pubmed
The in vitro anticancer analysis was performed using 9 human cancer cell lines incubated with organic and aqueous extracts of A. - pubmed
Investigation of ethanol - induced impairment of spatial memory in gamma2 heterozygous knockout mice . - pubmed
PURPOSE : To investigate hemodynamic response to volume replacement with saline solution and hypertonic hydroxyethyl starch in hypovolemic dogs . - pubmed
Recurrent malignant peripheral nerve sheath tumour in a patient with neurofibromatosis Type 1 : a case report . - pubmed
We report a 58 - year - old patient with known neurofibromatosis Type 1 ( NF-1 ) who presented with an aggressive recurrent malignant peripheral nerve sheath tumour and spinal cord compression 5 weeks after undergoing tumour excision with thoracic ( T)6 - 7 laminectomy . - pubmed
The case and literature review are instructive to those following NF-1 patients with regards to screening for , and management of , malignant conversion of plexiform neurofibroma . - pubmed
STUDY OBJECTIVE : Past studies have shown that acute experimental reduction of time in bed in otherwise healthy , non - sleepy people leads to hyperalgesia . - pubmed
We hypothesized that otherwise healthy , sleepy people may also exhibit hyperalgesia relative to their non - sleepy counterparts . - pubmed
CONCLUSION : This suggests that sleepy individuals experience hyperalgesia in response to a painful stimulus when compared with non - sleepy individuals . - pubmed
OBJECTIVES : The purpose of this study was ( i ) to document the average depths and density of adnexal structures in non - lasered facial and non - facial body skin ; ( ii ) to determine injury in ex vivo human thigh skin with varying fractional laser modes ; and ( iii ) to evaluate the clinical safety and efficacy of treatments . - pubmed
Histological studies of samples from human thigh skin demonstrated that increased fluencies in the superficial , deep and combined mode resulted in predictable deeper levels of ablations and thermal injury . - pubmed
Here we report that nicotine ( 1 microM ) suppresses in vitro hyperexcitability of colonic dorsal root ganglia ( DRG ) ( L(1)-L(2 ) ) neurons in the dextran sodium sulfate ( DSS)-induced mouse model of acute colonic inflammation . - pubmed
Nicotine gradually reduced regenerative multiple - spike action potentials in colitis mice to a single action potential . - pubmed
This clinical case reports a 31 - year - old man with bilateral long finger metacarpal head avascular necrosis , treated with osteochondral mosaicplasty . - pubmed
Studies have consistently demonstrated that early EN is safe and well tolerated , showing a reduction in wound morbidity and healing , fewer septic complications , diminished weight loss , and improved protein kinetics in patients administered early EN . - pubmed
Both of them significantly extended the replicative lifespan of the K6001 yeast strain . - pubmed
BACKGROUND : This study compared the results of patients treated for ulnar impaction syndrome using an ulnar shortening osteotomy ( USO ) alone with those treated with combined arthroscopic debridement and USO . - pubmed
CONCLUSIONS : Both USO alone and combined arthroscopic TFCC debridement with USO improved the wrist function and reduced the level of pain in the patients treated for ulnar impaction syndrome . - pubmed
Acute inflammation triggered by enteric pathogens , such as Salmonella enterica serotype Typhimurium ( S. - pubmed
Herein , we analyzed ciliary ultrastructural defects in 22 children with MPP and determined the association of these defects with prognosis . - pubmed
The recovery time in patients with multiple abnormalities was longer than that in patients with single abnormality . - pubmed
A preliminary sketch of horn cancer transcriptome in Indian zebu cattle . - pubmed
Horn cancer , a type of squamous cell carcinoma , in zebu cattle is an expensive affair in Indian agriculture sector , which accounts for 83.34 % of total tumors found . - pubmed
We employed Roche 454 next generation sequencing platform to sequence Bos indicus cancerous and normal horn tissue transcripts . - pubmed
This study for the first time provides primary transcriptome sketch of Bos indicus horn cancer tissue , and also demonstrates the suitability of the 454 sequencer for transcriptome analysis , which supports the concept of varied gene expression in cancerous condition . - pubmed
In addition , we compared estrogen and testosterone levels in Japanese postmenopausal women with and without fractures . - pubmed
Estrogen concentrations in postmenopausal women were associated with BMD ; however , no association was found between sex hormone levels and the presence of fractures . - pubmed
Patients either transmitted electrocardiograms ( ECGs ) daily or upon experiencing cardiac symptoms . - pubmed
Of the 70 patients included , 25 were diagnosed with PAF . - pubmed
Patients with stroke had more episodes of AF ( 56.5 + -106.3 versus 6.7 + -85.9 , p=0.685 ) and symptomatic AF episodes ( 9.8 + -17.5 versus 4.9 + -8.1 , p=0.381 ) than the patients who did not have a stroke , but the differences were not statistically significant because of the low numbers of patients and episodes . - pubmed
Clinical trials established aspirin plus clopidogrel as the standard dual anti - platelet therapy in patients with ACS and patients undergoing percutaneous coronary intervention ( PCI ) with stenting . - pubmed
Prasugrel is the next approved thienopyridine that has shown superior efficacy in ACS patients undergoing PCI in comparison to clopidogrel , although at the cost of a higher bleeding risk . - pubmed
The data so far suggests that ticagrelor has a wider applicability in usage in patients with ACS as compared to prasugrel . - pubmed
Results of the present study demonstrate that IRL-1620 , administered on day 1 , provides significant neuroprotection till 7 days after the induction of cerebral ischemia in rats . - pubmed
Risk of thiazide - induced hyponatremia in patients with hypertension . - pubmed
Facial appearance reflects human familial longevity and cardiovascular disease risk in healthy individuals . - pubmed
In DKO mice , diffuse lymphocytic infiltration was seen in submandibular glands , a major target of pSS , by age 6 wk , progressing to severe inflammation by age 12 wk . - pubmed
Curcumin is a polyphenol derived from the rhizome of Curcuma longa whose pharmacological effects include antioxidant , anti - inflammatory and anti - cancer properties . - pubmed
Cisplatin neurotoxicity is clinically evident in patients that have undergone a full course of chemotherapy and develop a peripheral neuropathy that may affect the treatment regimen and the patient 's qualify of life . - pubmed
All but two of these patients developed BMs after becoming castration - resistant . - pubmed
Effects of pitavastatin and atorvastatin on lipoprotein oxidation biomarkers in patients with dyslipidemia . - pubmed
METHODS AND RESULTS : The VISION ( Value of oxIdant lipid lowering effect by Statin InterventiON in hypercholesterolemia ) Trial randomized patients with hypercholesterolemia to 12 - week administration of pitavastatin 2 mg / day ( n = 21 ) or atorvastatin 10 mg / day ( n = 21 ) and a variety of lipoprotein oxidative biomarkers were measured . - pubmed
CONCLUSIONS : The VISION study describes the first comparison on lipoprotein oxidation biomarkers between pitavastatin and atorvastatin and suggests diverse effects on lipoprotein oxidation markers in patients with hypercholesterolemia . - pubmed
CT scan showed pneumothorax in 92 patients . - pubmed
Osteomalacia and insufficiency fracture in a hemodialysis patient with autosomal dominant polycystic kidney disease . - pubmed
A 61 - year - old Japanese woman on hemodialysis with autosomal dominant polycystic kidney disease ( ADPKD ) was admitted to the hospital with gluteal pain . - pubmed
This case emphasizes that vitamin D deficiency and malnutrition can cause osteomalacia in dialysis patients , even if calcium ( Ca ) and phosphate ( P ) levels are controlled by calcium carbonate . - pubmed
A 30 - year - old man with fever , myalgias , arthritis , and rash . - pubmed
We reviewed 111 patients diagnosed with early - stage ovarian cancer who had undergone primary surgery at Hacettepe Hospital between 1984 and 2001 , using diagnostic criteria from the WHO-2003 classification . - pubmed
FIGO - stage and mitotic count were significant for survivals of 59 patients with cancer . - pubmed
The patients with stage - II cancer had 5.65 times more risk of recurrence than stage - I cancer . - pubmed
National estimates of GW burden in sexually transmitted disease ( STD ) clinic settings are useful to provide a baseline assessment to monitor and evaluate reductions in GW and serve as an important early measure of human papillomavirus ( HPV ) vaccine impact in this population . - pubmed
Given the opportunity for prevention with a quadrivalent HPV vaccine , STD clinics may be an ideal setting for monitoring trends in GW prevalence among men ( MSW and MSM ) . - pubmed
SUBJECTS AND METHODS : We reviewed medical records retrospectively for 325 patients diagnosed with IE between January 1 , 1987 , and March 31 , 2012 . - pubmed
Among patients with head and neck squamous cell carcinoma with a negative neck who are initially treated with ( chemo)radiotherapy , a number of cases will recur locally without obvious neck recurrence . - pubmed
The risk of occult neck node metastasis in a clinically rN0 patient correlated with tumor site and T stage . - pubmed
For patients with more advanced laryngeal recurrences or recurrence at other high - risk sites , neck dissection could be considered for the rN0 patient , particularly if the neck was not included in the previous radiation fields . - pubmed
Tumorigenesis in vivo was assessed using a mouse xenograft model . - pubmed
Antimicrobial Susceptibility Pattern of Burkholderia cepacia Isolates from Patients with Malignancy . - pubmed
In this report , we describe a case of mesenteric venous thrombosis in a young woman caused by a vaginal contraceptive ring . - pubmed
It seems logical to assume a similar beneficial effect in children hospitalised for an acute asthma exacerbation . - pubmed
MAIN RESULTS : Seven randomised trials were included , four of which reported usable data on 472 children with asthma one to 18 years of age who were admitted to paediatric wards . - pubmed
These findings support current national and international recommendations indicating that healthcare practitioners should refrain from using anticholinergics in children hospitalised for acute asthma . - pubmed
METHODS : This study involved 33 patients ( 20 high - grade and 13 low - grade gliomas ) . - pubmed
OBJECTIVE : To assess the relationship between AD - related pathological changes in human brain tissue , ventricular and lumbar CSF , and brain interstitial fluid ( ISF ) . - pubmed
METHODS : Altogether 11 patients with suspected idiopathic normal pressure hydrocephalus underwent frontal cortical brain biopsy , 24 - h intraventricular pressure monitoring , and a microdialysis procedure . - pubmed
We therefore intended to study the relationship between the ventilatory response to CO2 and the impairment of lung function in DM1 patients . - pubmed
Sixty - nine DM1 patients were prospectively investigated ( 43.5 + - 12.7 years ) . - pubmed
Thirty - one DM1 patients ( 45 % ) presented a ventilatory restriction , 38 ( 55 % ) were hypoxaemic and 15 ( 22 % ) were hypercapnic . - pubmed
Ventilatory response to CO2 was neither different among restricted / non - restricted patients ( p = 0.2395 ) nor among normoxaemic / hypoxaemic subjects ( p = 0.6380 ) . - pubmed
The reduced ventilatory response to CO2 in DM1 patients appeared independent of lung function impairment and respiratory muscle weakness , suggesting a central cause of CO2 insensitivity . - pubmed
Ginseng Purified Dry Extract , BST204 , Improved Cancer Chemotherapy - Related Fatigue and Toxicity in Mice . - pubmed
A large proportion of cancer patients experience cancer - related physical and central fatigue so new strategies are needed for treatment and improved survival of these patients . - pubmed
PURPOSE : To investigate the causes of late - onset , progressive neurological deficits in patients with severe angular kyphosis caused by spondylitis secondary to tuberculosis ( TB spondylitis ) . - pubmed
METHODS : From 2000 to 2011 , 36 patients with severe angular kyphosis secondary to TB spondylitis ( TB kyphosis ) were enrolled in the study . - pubmed
All patients had late - onset , progressive neurological deficits . - pubmed
Group A ( n = 25 , 69.4 % ) comprised patients whose neurological deficits resulted from the kyphosis itself . - pubmed
Patients in group B ( n = 11 , 30.6 % ) had developed neurological symptoms related to a lesion cephalad or caudal from the kyphosis . - pubmed
CONCLUSIONS : In their evaluation of paraplegic patients , spine surgeons should consider the many potential causes of late - onset neurological deficits in TB spondylitis to avoid performing unnecessary surgery . - pubmed
Lugol chromoendoscopic screening for esophageal dysplasia / early squamous cell carcinoma in patients with esophageal symptoms in low - risk region in China . - pubmed
In the chromoendoscopy group , 213 patients had unstained lesions of & gt;0.5 cm , the detection rates of dysplasia / early carcinoma were 5.3 % ( 4/76 ) in those with lesions of 0.5 - 1.0 cm , and 37.2 % ( 51/137 ) in those with lesions & gt;1.0 cm ( chi2=21.46 , P<0.001 ) . - pubmed
Forty - two critically ill patients requiring PiCCO - Plus cardiac output monitoring were prospectively studied . - pubmed
Thirty older adults ( 69.0 + - 4.2 years of age ) were studied on two separate occasions on both the WBB and a stationary isometric dynamometer ( SID ) . - pubmed
Trauma date , patient gender and age , mechanism and anatomic topography of injury , surgical management , need for surgical re - intervention , hospitalization period , postoperative complications , mortality and limb amputation rates were analyzed . - pubmed
RESULTS : One hundred seventy - three patients with 255 vascular injuries were analyzed ; 95.95 % were male ( p<0.05 ) , mean age of 28.92 years ; 47.4 % were caused by firearm projectiles ( p<0.05 ) ; topographic distribution : 45.66 % lower limbs ( p<0.05 ) , 37.57 % upper limbs , 6.94 % abdominal , 5.2 % thoracic and 4.62 % were cervical vascular injuries ; 51.42 % of patients required hospitalization for seven days or less ( p<0.05 ) ; limb amputation was necessary in 15.6 % and the overall mortality was 6.36 % . - pubmed
We report herein on an ex vivo conjunctival inflammation and squamous metaplasia model by culturing human conjunctival tissues at an air - liquid interface for up to 8 days to study the effects of minocycline on inflammation and squamous metaplasia . - pubmed
CONTEXT : 3,5 - Diiodo - L - thyronine ( 3,5 - T2 ) is a thyroid hormone metabolite which exhibited versatile effects in rodent models , including the prevention of insulin resistance or hepatic steatosis typically forced by a high - fat diet . - pubmed
Salivary oxidant/ antioxidant status and hematological parameters in patients with recurrent aphthous stomatitis . - pubmed
METHODS : This case - control study consisted of 28 patients with RAS and 28 age and sex -matched control without RAS . - pubmed
Detection of CHLAMYDIA PSITTACI in feral pigeons ( COLUMBA LIVIA DOMESTICA ) in Slovakia and their characterisation . - pubmed
INTRODUCTION AND OBJECTIVES : Chlamydia psittaci , an obligate intracellular bacterium , which is the etiologic agent of avian chlamydiosis in birds and ornithosis / psittacosis in humans , has been reported to be one of the most common pathogens found in feral pigeons worldwide , and thus constitutes a zoonotic risk . - pubmed
We have treated a series of 15 patients with 17 fractures of the condylar head , in which the use of ultrasound - activated resorbable fixation has provided adequate strength and stability during early healing . - pubmed
MATERIALS AND METHODS : Sixty - one patients ( 43 men and 18 women ; mean [ + - SD ] age , 65.8 + - 8.6 years ; age range , 44 - 82 years ) with 71 HCCs ( mean [ + - SD ] size , 2.8 + - 0.9 cm ; range , 0.7 - 4.2 cm ) underwent combined TACE and RFA . - pubmed
Aggressive intrasegmental recurrence was observed in one patient ( representing 1.4 % of all treated HCCs and 4.5 % of periportal HCCs ) after treatment of a 4.0 - cm periportal HCC . - pubmed
HIV / AIDS knowledge , attitudes and behaviour of persons with and without disabilities from the Uganda Demographic and Health Survey 2011 : Differential access to HIV / AIDS information and services . - pubmed
Recommendations are also made for the inclusion of disability measures in Uganda 's AIDS Indicator Survey to provide cyclical and systematic data on disability and HIV / AIDS , including HIV prevalence amongst persons with disabilities . - pubmed
Multiple stressors including contaminant exposure and parasite infection predict spleen mass and energy expenditure in breeding ring - billed gulls . - pubmed
The objective of this study was to determine how multiple physiological stressors ( parasite infection and contaminant exposure ) and natural challenges ( energy - demanding activities and weather conditions ) may affect DEE in nesting ring - billed gulls ( Larus delawarensis ) exposed to high concentrations of persistent organic contaminants ( POPs ) . - pubmed
Fighting tuberculosis by drugs targeting nonreplicating Mycobacterium tuberculosis bacilli . - pubmed
Drugs were less effective in C3HeB / FeJ mice forming caseous granulomas . - pubmed
Clinical implications of blood eosinophil count in patients with non - asthma - COPD overlap syndrome COPD . - pubmed
We investigated the clinical implications of the blood eosinophil count in patients with non - ACOS COPD . - pubmed
Cancer of the Breast in a Man . - pubmed
Hepatic performance of the patients , thrombotic events , inflammatory disorders and autoimmune system activation must be the main concerns together with necessary precautions . - pubmed
Methods : Our retrospective monocentric study was based on 130 patients followed on a regular basis , with acromegaly controlled by medical treatments or cured by surgery or radiation technique . - pubmed
Conclusions : The follow - up of glucose disorders needs to be maintained on a long - term basis in patients controlled for acromegaly . - pubmed
Materials and Methods : Sixty - one patients with cervical cancer were included in this study from June 30 , 2015 to April 30 , 2017 . - pubmed
RESULTS : There were 534 patients with aortic stenosis , 254 with aortic regurgitation , 61 with aortic stenoregurgitation , 19 with infective endocarditis , and 5 with a previous aortic valve procedure . - pubmed
Fifteen patients needed reoperation ( 13 infective endocarditis , 1 break of thread , and 1 tear of cusp case ) . - pubmed
CONCLUSIONS : The midterm outcomes of AVNeo using autologous pericardium were satisfactory in 850 patients with various aortic valve diseases . - pubmed
Biological trials of peritoneally injected Abu - TGIRIS - Abu - NH2 gave an evidence of its better efficacy versus immunocortin in a test for suppression of the experimental autoimmune encephalomyelitis ( EAE ) in Dark Agouti ( DA ) rats . - pubmed
Comparison of non - invasive assessment of liver fibrosis in patients with alpha1 - antitrypsin deficiency using magnetic resonance elastography ( MRE ) , acoustic radiation force impulse ( ARFI ) Quantification , and 2D - shear wave elastography ( 2D - SWE ) . - pubmed
PURPOSE : Although it has been known for decades that patients with alpha1 - antitrypsin deficiency ( AATD ) have an increased risk of cirrhosis and hepatocellular carcinoma , limited data exist on non - invasive imaging - based methods for assessing liver fibrosis such as magnetic resonance elastography ( MRE ) and acoustic radiation force impulse ( ARFI ) quantification , and no data exist on 2D - shear wave elastography ( 2D - SWE ) . - pubmed
METHODS : Fifteen clinically asymptomatic AATD patients ( 11 homozygous PiZZ , 4 heterozygous PiMZ ) and 16 matched healthy volunteers were examined using MRE and ARFI quantification . - pubmed
This study was aimed to examine the potential treatment effect of intravenous lipid emulsion on rat liver tissue in the toxicity of malathion . - pubmed
RESULTS : The prevalence of AF in HCM patients has gradually increased to 1.6 - fold from 13.4 % in 2005 to 20.9 % in 2015 . - pubmed
The prevalence of stroke in HCM patients was approximately 10 % , while that in HCM patients with AF was about 20 % . - pubmed
We report the first case of a gasless robot - assisted nipple - sparing mastectomy and immediate reconstruction in a patient with early breast cancer . - pubmed
Fisetin suppresses migration , invasion and stem - cell - like phenotype of human non - small cell lung carcinoma cells via attenuation of epithelial to mesenchymal transition . - pubmed
Cautious approach in intraoperative inspired oxygen fraction is required for patients susceptible to postoperative pulmonary complications . - pubmed
Cell death is a common driver of human disease and is frequently studied in a variety of in vitro settings . - pubmed
All patients fulfilling the in-/exclusion criteria and presenting full data sets on lesion diameter , lesion color , as well as pain perception for baseline ( day 0 ) and 4 and 7 days after treatment were enrolled into the presented study . - pubmed
Both groups showed equal distribution in patient 's age , sex and presented a similar mean lesion size ( 3.0 + - 1.0 mm ) , lesion color distribution as well as pain perception at baseline . - pubmed
All patients showed significant normalization of lesion color , reduction of pain , and lesion dimension within the course of their treatment . - pubmed
METHODS : A 16 - week RCT training intervention was conducted in overweight premenopausal women randomized into three groups : a team handball training group without prior experience ( UN ; n = 13 ) , a team handball group with prior experience ( EXP ; n = 10 ) , and an inactive control group ( CON ; n = 9 ) . - pubmed
Moreover , the synthesized nanoparticles ( NPs ) demonstrate potent cytotoxicity against human U87 glioblastoma cells by inducing cell apoptosis via triggering intracellular ROS overproduction . - pubmed
The full - length genome of four Moroccan vvIBDV strains was determined , in order to get a more exhaustive molecular characterization allowing to conduct the evolution time scale and speculations on their origin . - pubmed
In a phylogenetic tree , nucleotide sequences of segment A and B formed a common branch with those vvIBDV references strains published in GenBank , but they clearly grouped into a distinct subcluster . - pubmed
The purpose of this study was to evaluate the effect of BMI percentile on sagittal alignment in AIS patients compared with nonscoliotic adolescents . - pubmed
METHODS : Posterior - anterior and lateral spinal radiographs of 1,551 AIS patients with a thoracic major curve ( Lenke 1 - 4 ) and 70 nonscoliotic adolescent patients were compared . - pubmed
RESULTS : Coronal plane deformity magnitude was not significantly different between the 4 categories of AIS patients ( p = .51 ) . - pubmed
This was also true in obese adolescents without spinal deformity ( p < .04 ) . - pubmed
Lumbar lordosis , pelvic incidence , and pelvic tilt were not significantly different between AIS patients in the four BMI percentile categories ( p > .07 ) . - pubmed
Pelvic incidence was significantly greater in AIS patients compared with nonscoliotic adolescents ( 54 + - 13 vs. 46 + - 11 ; p = .01 ) . - pubmed
CONCLUSION : Increased BMI percentile is associated with increased thoracic kyphosis in AIS patients and nonscoliotic adolescents . - pubmed
AIS patients have an increased pelvic incidence compared with nonscoliotic adolescents ; however , this variable is not influenced by body mass . - pubmed
A 45 - year - old Japanese man presenting with leg purpura , abdominal pain , and arthralgia was diagnosed with IgA vasculitis . - pubmed
The blood loss was approximately 10800ml and the patient received transfusions of 48 units of concentrated red blood cells , 18 units of fresh frozen plasma , and 30 units of concentrated platelets . - pubmed
Rarely , massive bleeding , perforation , intussusception , and/or intestinal obstruction occur in the gastrointestinal tract and these complications affect patients ' prognoses . - pubmed
The clinical course in the present patient indicated that severe bleeding from the gastrointestinal tract can occur even after symptom remission in patients with IgA vasculitis . - pubmed
Comparing wound complications associated with midline and flank approaches for spaying cats . - pubmed
Using a non - randomized clinical study design we assessed adult rituximab naive patients with B - cell lymphoid malignancies from January 2017 to July 2019 . - pubmed
The envelope following response ( EFR ) has been proposed as a non - invasive marker of synaptopathy in animal models . - pubmed
The combined analysis of simulations and experimental data proposes that the DBEFRs extracted from the [ 2 - 6]-kHz frequency band is a sensitive and frequency - specific measure of synaptopathy in humans . - pubmed
Rebuttal to letter " Is thromboprophylaxis with high - dose enoxaparin really necessary for COVID-19 patients ? - pubmed
Members of Fusarium graminearum species complex ( FGSC ) are the major pathogens that cause Fusarium head blight ( FHB ) in cereals worldwide . - pubmed
asiaticum with the NIV chemotype was less aggressive than that with the 3ADON chemotype in wheat , while the NIV - producing strains were more virulent than the 3ADON - producing strains in rice . - pubmed
Chronic kidney disease ( CKD ) patients with secondary hyperparathyroidism ( SHPT ) have an increased risk of cardiovascular disease ( CVD ) . - pubmed
Cinacalcet was administered to six SHPT patients for a period of 8 weeks . - pubmed
Furthermore , this aerogel exhibits the shortest clotting time and lowest blood loss in rat hemorrhage model . - pubmed
Radiotherapy improves local and regional control in patients with breast cancer , and it could even improve relapse - free survival and overall survival in patients with nodal disease . - pubmed
The toxicity of this treatment in most cases is mild and transient , but in a low percentage of patients , radiotherapy - induced tumors may develop . - pubmed
CASE PRESENTATION : Seven Colombian patients treated for breast cancer at our institution developed radiotherapy - induced tumors between 2008 and 2018 . - pubmed
Six patients had locally advanced tumors at the time breast cancer was diagnosed , and all of them received neoadjuvant or adjuvant chemotherapy and radiotherapy . - pubmed
Septic arthritis post anterior cruciate ligament reconstruction due to Clostridioides difficile . - pubmed
Clostridioides difficile is an obligate anaerobe ubiquitous in the environment and is of particular interest in the healthcare setting as a cause of healthcare associated infection usually presenting with colitis . - pubmed
Blends of Gelucire 44/14 and coconut oil were employed as lipid excipients to obtain suppository formulations with self - emulsifying properties , which were then tested in a TNBS ( 2,4,6 - trinitrobenzenesulfonic acid ) induced rat colitis model . - pubmed
Effect of Secondary Prevention Medication on the Prognosis in Patients With Myocardial Infarction With Nonobstructive Coronary Artery Disease . - pubmed
The role of secondary prevention therapy in patients with MINOCA remains unclear . - pubmed
This study aimed to evaluate the associations between secondary prevention medications and outcomes in patients with MINOCA . - pubmed
A total of 259 patients with MINOCA were consecutively enrolled . - pubmed
About 19.1 % of patients with MINOCA suffered adverse events during the follow - up period . - pubmed
Objective : Catheter ablation combined with left atrial appendage closure ( LAAC ) has emerged as a promising strategy for atrial fibrillation ( AF ) patients at high risk for stroke or with contraindications for oral anticoagulants ( OACs ) . - pubmed
Methods : From October 2015 to December 2017 , a total of 76 consecutive non - valvular , drug - refractory AF patients who underwent a combined procedure of CBA and LAAC are included . - pubmed
With a mean follow - up time of 23.7 + - 11.0 months , the recurrence of atrial arrhythmia was recorded in 35 patients ( 48.0 % ) . - pubmed
Among the 72 patients ( 94.7 % ) who underwent TEE , one patient ( 1.4 % ) had device - related thrombosis and one patient ( 1.4 % ) had prominent residual flow ( over 3 mm ) . - pubmed
This study examined the effect of acupuncture stimulation in the vicinity of the cervical - sympathetic ganglion on respiratory function in humans . - pubmed
In Sr2 + - Tyrode lacking Ca2 + all three toxins exhibited the same immediate depression followed by facilitation in the rat and mouse diaphragms , but the final blocking activity was only 3 - 10 % with beta - bungarotoxin and crotoxin and was 30 % with taipoxin . - pubmed
The authors report the results of a randomized study in which comparison was made between two different kinds of treatment in patients affected by uncomplicated duodenal ulcer endoscopically diagnosed . - pubmed
Chronic unremitting , generally symmetric , erosive polyarthritis was studied in 8 dogs . - pubmed
The disease had clinical , serologic , radiographic , and pathologic changes similar to those of rheumatoid arthritis of man . - pubmed
The condition occurred mainly in smaller breeds of dogs , with time of onset from 8 months to 8 years of age , Characteristic radiographic changes were seen in the joints several weeks to several months after the appearance of the initial lameness . - pubmed
The effect of various doses of specific serum administered in passive immunization on the formation of primary and secondary adaptive immunity in mice of the CBA strain was studied . - pubmed
Scalp infections occurred in children and were due either to Microsporum canis or Microsporum ferrigineum . - pubmed
Over the past 20 years the Orthopaedic Oncology Unit of the Massachusetts General Hospital has performed over 660 massive cadaveric allograft transplantations , mostly for patients with bone tumors . - pubmed
To determine whether the oats - related extra spots were derived from mycotoxin contamination , two groups of rats were fed either Wayne diet or Wayne diet containing zearalenone ( 0.05 mg / kg ) for three weeks . - pubmed
It probably results from reactivation of infection by Epstein - Barr virus ( EBV ) and usually presents as bilateral white patches on the lateral borders of the tongue . - pubmed
Diagnosis of hairy leukoplakia should normally be confirmed by demonstrating EBV in the koilocyte - like cells by immunocytochemistry or DNA in situ hybridization . - pubmed
[ Possibility of ovulation induction using naloxone in women with hypothalamic amenorrhea ] . - pubmed
Within the study we treated 6 women suffering from hypothalamic amenorrhea with 4 mg naloxone intravenous daily . - pubmed
The other women ( non - responder in Naloxone - Test ) reaches a follicular growth till 17 mm follicle diameter following in preterm atresia during therapy . - pubmed
This decrease was markedly delayed in the liver of hypothyroid rats . - pubmed
This increase was markedly delayed in the liver of hypothyroid rats . - pubmed
Mice were then observed for survival or sacrificed at day 21 after tumor inoculation to determine size of primary tumor , numbers and size of lung metastases , and other hematological parameters including numbers of granulocyte - macrophage progenitor cells ( CFU - gm ) . - pubmed
Human papillomaviruses are oncogenic viruses that have been found in a variety of epithelial neoplasias . - pubmed
Human papillomavirus type-16 DNA was found in four of the five tumors , including two tumors that contained both type-16 and type-18 DNA . - pubmed
[ Clinical observations on the treatment of hookworm , Ascaris and Trichuris infection with oxibendazole ] . - pubmed
The purpose of this study was to determine what advantages the use of paramagnetic contrast material might have in evaluating patients clinically suspected of having spinal infection . - pubmed
Our results showed the following advantages of gadolinium - enhanced MR : it ( a ) provided excellent anatomical delineation of all epidural abscesses , routinely differentiating them from the adjacent compressed thecal sac even when this was not possible by noncontrast MR ; ( b ) increased observer confidence in the diagnosis of disk space infection and osteomyelitis in patients with equivocal noncontrast MR ; ( c ) localized those portions of paraspinal masses most likely to yield a positive percutaneous biopsy ; and ( d ) identified active infections from those that had responded adequately to antibiotic therapy . - pubmed
We studied transepithelial potential difference ( PD ) in normal persons , patients with chronic disease , and patients with cystic fibrosis ( CF ) , using the technique described by Knowles and co - workers . - pubmed
These data confirm the observation that patients with CF have hyperpolarized nasal epithelia that demonstrate greater change in response to amiloride than that in non - CF controls . - pubmed
In a randomized clinical trial the effects of selective digestive decolonization ( SDD ) on the frequency of pneumonia and sepsis and the rate of lethality as well as the resistance quota and colonization of bacteria were studied in 102 surgical ICU - patients requiring prolonged mechanical ventilation . - pubmed
Immunologic patterns in CAPD patients with peritonitis . - pubmed
In a third of the patients these cysts are associated with malformations of CNS a./o . - pubmed
Nude rats and thymus - grafted nude rats were susceptible to infection with T. - pubmed
mentagrophytes but only thymus - grafted nude rats cleared the dermatophytosis . - pubmed
Clearance of the fungal infection took twice as long ( approximately 60 days ) in thymus - grafted nude rats when compared with heterozygous euthymic ( + /RNU ) controls ( approximately 35 days ) . - pubmed
Following clearance of the primary dermatophytosis , peritoneal exudate cells ( PEC ) were adoptively transferred from either thymus - grafted or heterozygous rats to nude rats . - pubmed
All heterozygous ( + /RNU ) rats , thymus - grafted nude rats ( 4/4 ) , and 8 of 12 PEC - recipient nude rats , which had cleared a primary dermatophytosis also expressed delayed - type hypersensitivity and elevated serum antibody titers to trichophytin antigen . - pubmed
mentagrophytes in the rat is T cell - dependent , and that the absence of functional T lymphocytes and not an epithelial defect results in chronic dermatophytosis in the nude rat . - pubmed
A cellular analysis of 330 middle ear effusions ( MEEs ) from children with otitis media with effusion ( OME ) was performed with the use of cytocentrifuge prepared smears and the results were compared with their clinical data . - pubmed
Information was sought on the phenotype of lymphoid cells causing lethal graft - vs - host disease ( GVHD ) in irradiated mice expressing whole or partial H-2 differences . - pubmed
Children and adolescents with IBD are at risk for serious thromboembolic complications . - pubmed
The Casella reaction and the permanganate - induced basophilia of human elastica . - pubmed
[ Corneal sensitivity in patients following surgery for retinal detachment ] . - pubmed
Subcutaneous growth and transplantation of the RS 1 rat tumor into adult unconditioned golden hamsters . - pubmed
Histaminemia in guinea pigs inoculated with Junin virus ] . - pubmed
The size of the second and third mandibular molar teeth of inbred mice is altered if the mice are fostered on a different strain . - pubmed
None of these persons had any signs of pancreatic disease . - pubmed
Sugar cataracts in Mongolian gerbil ( Meriones unguiculatus ) . - pubmed
Mongolian gerbils ( Meriones unguiculatus ) given a 50 % galactose diet developed cataracts similar to those produced in rats maintained on the same diet . - pubmed
The first sign of a cataract appeared 24 hr after feeding gerbils on the high galactose diet . - pubmed
The pace of cataract maturation was observed to be about twice of that in rats , although the blood galactose levels were similar in the two species . - pubmed
The gerbil thus appears to be another suitable model for the study of sugar cataracts . - pubmed
[ Initial experience with an operation for pulmonary artery narrowing in young children with patent common atrioventricular canal ] . - pubmed
METHODS AND RESULTS : Hamster hearts were obtained for RNA isolation and analysis and in situ hybridization from two groups : normal control animals ( n = 4 ) and untreated cardiomyopathic hamsters ( n = 5 ) . - pubmed
The case of a 77 - year - old woman with a 6/5/4.5 cm , mobile , hard , white - yellowish tumour associated with axillary adenopathy , with a progressive evolution in the upper external frame of the right breast is presented . - pubmed
It is proposed that the phenomena of psychosis ( including negative symptoms ) can be understood as part of the diversity of human personality structure generated by a process of sexual selection acting on a sexual dimorphism for cerebral asymmetry . - pubmed
The dogs were followed for endocrine and exocrine pancreatic insufficiency . - pubmed
Two dogs ( 13 % ) developed radiation - induced morbidity which consisted of a common bile duct stenosis and an enterocolic fistula , as was confirmed at autopsy after 8 and 18 months , respectively . - pubmed
After a follow - up of 1 year , none of the dogs had developed pancreatitis , diabetes or exocrine insufficiency . - pubmed
The first , that yeast respiratory activity protects anaerobic rumen bacteria from damage by O2 , was tested using different strains of yeast that had previously been shown to have differing abilities to increase the viable count of rumen bacteria . - pubmed
Forty - three patients with T3 glottic carcinomas and treated by a combination of total laryngectomy and radiotherapy were studied . - pubmed
The difference in peristomal recurrence between the tracheostomy and non - tracheostomy patients was not statistically significant . - pubmed
In this case a patient ( aged 57 years ) suffering from a recurrent larynx papillomatosis was treated with PDT . - pubmed
After treatment the patient was admitted to an intensive care unit for 24 h. 3 h after photoradiation , general urticarial wheals arose , as well as tachycardia and a decrease in blood pressure followed by all the signs of serious anaphylaxis . - pubmed
Moreover , QA produced a marked hyperactivity , an inability to use the forelimbs to retrieve food pellets in a staircase test , increased the latency of the rats to remove adhesive stimuli from their paws , and decreased the number of steps taken in a bracing test that assessed motor rigidity . - pubmed
A 60 - year - old man underwent transfrontal surgery for a macroadenoma of the pituitary which presented with chiasmal compression , and immunohistochemical examination of the resected specimen revealed a corticotrophic tumour . - pubmed
PATIENTS AND METHODS : A review of 127 patients with non - metastatic osteosarcoma of the extremity , treated between March 1983 and June 1986 , was performed . - pubmed
None of the patients who relapsed with local or distant recurrences other than lung metastasis are now alive . - pubmed
All of the patients who were not surgically treated had disease progression and died within 40 months after the first recurrence . - pubmed
RESULTS : In all 35 cases of adults melanoma malignum was diagnosed and confirmed anatomopathologically . - pubmed
In 7 among 20 children the appearance of tumor was not confirmed by anatomopathologic findings . - pubmed
CONCLUSIONS : Special attention should be paid to the improvement of intraocular tumor diagnosis , particularly in children . - pubmed
DATA SYNTHESIS : Low - risk patients with single - vessel coronary artery disease and normal left ventricular function had greater alleviation of symptoms with PTCA than with medical treatment ; mortality rates and rates of myocardial infarction were unchanged . - pubmed
In high - risk patients ( risk was defined by severity of ischemia , number of diseased vessels , and presence of left ventricular dysfunction ) , improvement of survival was greater with CABG than with medical therapy . - pubmed
In moderate - risk patients with multivessel coronary artery disease ( most had two - vessel disease and normal left ventricular function ) , PTCA and CABG produced equivalent mortality rates and rates of myocardial infarction . - pubmed
In moderate - risk patients , PTCA and CABG produce similar mortality rates and rates of myocardial infarction but PTCA - treated patients require more revascularization procedures . - pubmed
We studied the electrophysiological parameters of motor performance in eight patients with multiple sclerosis and troublesome fatigue , before and after treatment with 3,4 - diaminopyridine . - pubmed
After a 3 - week course of 3,4 - diaminopyridine ( 25 - 60 mg / day ) , six out of the eight patients reported substantial improvement in fatigue and the group showed slightly less fatigue on the exercise test . - pubmed
A group of 20 patients underwent plastic surgery for inguinal hernia . - pubmed
This reflex is potentiated by shock exposure and associative shock conditioning ( in animals and human volunteers ) and unpleasant pictures ( in human volunteers ) . - pubmed
Investigation of oxidant stress and vasodepression to glyceryl trinitrate in the obese Zucker rat in vivo . - pubmed
We examined the relationship between oxidant stress and the vasodepressor activity of glyceryl trinitrate ( GTN ) in vivo , including rapid GTN tolerance development , in 13 - week old obese and age - matched lean Zucker rats which had been maintained for 4 weeks on either control diet or diets enriched with the lipophilic , chain - breaking antioxidants vitamin E ( 0.5 % w w(-1 ) ) or probucol ( 0.5 % w w(-1 ) ) or the superoxide anion scavenger tiron ( 1 % w v(-1 ) in drinking water ) . - pubmed
The basal plasma level of the isoprostane 8 - epi - PGF2alpha , an in vivo marker of lipid peroxidation , was elevated by approximately 5 fold in the obese Zucker rat and markedly reduced by dietary lipophilic antioxidants and depressed by dietary tiron . - pubmed
, was impaired in obese animals and completely restored by dietary antioxidants . - pubmed
appeared more severe in obese animals . - pubmed
However , rapid nitrate tolerance was not affected by dietary antioxidants in either the obese or lean Zucker rat . - pubmed
We therefore provide evidence that elevated oxidant stress in the obese Zucker rat is associated with an impairment in nitrate vasodepressor activity . - pubmed
OBJECTIVE : To evaluate the incidence and mechanism of beta - lactam adverse reactions during an 8 - year period in all episodes of suspected infective endocarditis in patients treated at a university - affiliated institution . - pubmed
A total of 121 low - velocity gunshot fractures were evaluated in 107 patients . - pubmed
Visual function deficits in children . - pubmed
In the past year , new work on sensory testing in preverbal infants has expanded our knowledge in three areas : 1 ) visual acuity testing in infants in varying levels of illumination ; 2 ) visual evoked cortical potential - evidence for binocular function in infantile esotropia ; and 3 ) a new time - efficient method to evaluate color vision in newborns and infants . - pubmed
We describe the case of a 7 - year - old girl who was clinically diagnosed as having a pontine glioma based on magnetic resonance imaging studies . - pubmed
Aerosol - derived airway morphometry and aerosol bolus dispersion in patients with lung fibrosis and lung emphysema . - pubmed
OBJECTIVE : Patients with lung emphysema show increased aerosol - derived dimensions of peripheral airspaces and increased aerosol bolus dispersion ( AD ) . - pubmed
DESIGN : This study was designed as a cross - sectional study in which airspace dimensions and AD in patients with emphysema and in patients with fibrosis were compared . - pubmed
Forty patients participated in the study : 20 patients had high - resolution CT ( HRCT)-proved lung emphysema and 20 patients had HRCT - proved lung fibrosis . - pubmed
RESULTS : Patients with lung emphysema showed normal dimensions of small airways but enlarged airspace dimensions in the lung periphery . - pubmed
AD was increased in patients with emphysema but was normal in patients with fibrosis . - pubmed
Patients with signs of general arteriosclerosis or those in whom upper abdominal resection has been performed previously may benefit from angiography . - pubmed
METHODS : Fifteen rats were randomized into three equally large groups and sustained to either thoracic laminectomy or to severe spinal cord compression trauma of the Th 8 - 9 segments . - pubmed
The non - trauma group contained laminectomized animals submitted to a hypothermic procedure in which the core temperature was reduced from 38 to 30 degrees C. The two trauma groups were either submitted to the same hypothermic procedure or kept normothermic during the corresponding time . - pubmed
CONCLUSIONS : This study demonstrates reduced axonal swelling in the peri - injury zones of spinal cord injured rats treated with systemic hypothermia . - pubmed
Patients with previous paroxysmal atrial fibrillation had lower left atrial appendage ejection fractions than patients in sinus rhythm without paroxysmal atrial fibrillation ( 33 + /- 14 vs. 47 + /- 14 % , p & lt ; 0.001 ) . - pubmed
More than half of the patients ( 7/13 [ 54 % ] ) with previous paroxysmal atrial fibrillation showed delayed and incomplete opacification of the left atrial appendage with Albunex . - pubmed
CONCLUSION : We conclude that paroxysmal atrial fibrillation causes left atrial appendage stunning , at least in some patients . - pubmed
OBJECTIVE : The aim of this systematic review was to evaluate all controlled trials of autogenic training ( AT ) as a means of reducing stress and anxiety levels in human subjects . - pubmed
This clinical report documents rectal toxicity from a large cohort of men treated by a single practitioner for adenocarcinoma of the prostate . - pubmed
Four patients ( 0.5 % ) reported Grade 3 rectal toxicity with rectal ulceration identified on colonoscopy at 1 year from implant . - pubmed
In 3 of the 4 patients the Grade 3 rectal toxicity has resolved spontaneously and 1 patient continues to heal at the time of this report . - pubmed
The authors report the case of a patient undergoing anterior pelvic exenteration for cancer of the urethra with sigmoid colon urinary diversion and vaginal reconstruction using a colonic segment . - pubmed
METHODS : Twelve patients with advanced malignant tumors involving the shoulder girdle or the proximal humerus underwent forequarter amputation ( FQA ) for palliative purposes . - pubmed
Lung metastases were the dominant cause of death in our patients . - pubmed
CONCLUSIONS : The results of FQA in our series point to its feasibility and the gain in quality of life and performance status in severely ill patients with advanced malignancies . - pubmed
Amblyomma testudinarium tick bite : one case of engorged adult and a case of extraordinary number of larval tick infestation . - pubmed
This paper reports two recent cases of tick bite due to Amblyomma testudinarium . - pubmed
To our knowledge , the latter case is the eleventh case of larval tick bites among all tick species and the fourth case with larval A. - pubmed
The term " strawberry gallbladder " refers to an anatomo - pathological aspect which is included in the wider chapter of gallbladder cholesterolosis . - pubmed
Splenic lymphoproliferative disorders in human T lymphotropic virus type - I endemic area of japan : clinicopathological , immunohistochemical and genetic analysis of 27 cases . - pubmed
Here we characterized splenic lymphomas in an human T lymphotropic virus type - I ( HTLV - I ) endemic area of Japan . - pubmed
Cases were divided into primary splenic lymphoma in 11 patients and secondary in 16 patients . - pubmed
Follow - up of 26 patients indicated that all but one patient with primary lymphoma were still alive ( range , 1 - 89 months ) and 8 of 15 patients with secondary lymphomas died due to the progression of malignant lymphoma ; the survival rate at 2 years was 50 % in these patients . - pubmed
In situ hybridization for Epstein - Barr virus ( EBV ) showed no reactivity of lymphoma cells , although a few small lymphocytes were positive for EBV . - pubmed
Hepatitis C virus was observed in 6 of 20 ( 30 % ) patients examined and 4 of 11 ( 36 % ) cases of primary splenic lymphoma . - pubmed
METHODS : 188 unselected patients , seen at an interdisciplinary dermatorheumatologic outpatient clinic , were clinically examined for the presence of ANT and possible associations to preexisting disease . - pubmed
The mean age of ANT patients was 57.5 + /- 8.2 years . - pubmed
CONCLUSIONS : ANT is not uncommon among patients attending a dermatorheumatologic outpatient clinic . - pubmed
We have performed a retrospective study including a non consecutive series of 92 patients presenting both BPH and inguinal hernia . - pubmed
Selected parameters of blood coagulation and fibrinolysis were evaluated in 20 patients with squamous cell carcinoma of the oral cavity ( stages T2/4 N0/3 M0 ) . - pubmed
We conclude that , in patients treated surgically because of carcinoma of the oral cavity , there might be increased activity of the fibrinolytic system both prior to and after operation . - pubmed
Semantic clustering in verbal fluency : schizophrenic patients versus control participants . - pubmed
BACKGROUND : Schizophrenic patients generate fewer words than healthy controls during verbal fluency tasks . - pubmed
METHODS : Twenty - four healthy controls and 24 patients with schizophrenia participated in six , 3 min semantic fluency tasks . - pubmed
The present study investigated the in vitro radiosensitizing effect of flavopiridol and the underlying molecular mechanisms in a murine ovarian cancer cell line , OCA - I. - pubmed
All patients responded well to therapy without locomotive disability , and persistent pain was uncommon . - pubmed
CONCLUSION : Septic sacroiliitis should be considered in peripartum patients who present with fever and severe localized pain . - pubmed
Diamond blackfan anemia stem cells fail to repopulate erythropoiesis in NOD / SCID mice . - pubmed
When tested in vivo , folate - targeted liposomes were found to deliver approximately 1.8 - fold more oligonucleotide to the livers of nude mice ( relative to the nontargeted PEG - containing formulations ) ; however , no improvement in KB tumor uptake was observed . - pubmed
Detection and characterization of measles virus strains in cases of subacute sclerosing panencephalitis in Croatia . - pubmed
Studies on acute disseminated encephalomyelitis produced experimentally in rhesus monkeys . - pubmed
We conclude that the development of cytomegaly is inhibited by Fe chelation and may be facilitated by an HCMV - induced increase in the LIP . - pubmed
OBJECTIVE : To investigate clinical effect , liver pathohistological changes ( including pathology , HBV markers in liver tissue ) in patients with chronic hepatitis B. - pubmed
METHODS : 70 patients of chronic hepatitis B were administered 100 mg Lamivudine orally daily for 1 year . - pubmed
First experience with gemtuzumab ozogamicin plus cytarabine as continuous infusion for elderly acute myeloid leukaemia patients . - pubmed
We treated with GO in combination with cytarabine as continuous perfusion nine elderly AML patients , either untreated ( five cases ) , or with relapsed / refractory disease ( four cases ) . - pubmed
Larger prospective studies are now warranted in order to better define the possible role of this regimen in the treatment of elderly AML patients . - pubmed
Experimentally induced ulcers and gastric sensory - motor function in rats . - pubmed
In earlier studies using positron emission tomography ( PET ) with the tracer alpha [( 11 ) C ] methyl - l - tryptophan ( AMT ) , we reported global and focal abnormalities of serotonin synthesis in children with autism . - pubmed
In the present study , we measured brain serotonin synthesis in a large group of autistic children ( n = 117 ) with AMT PET and related these neuroimaging data to handedness and language function . - pubmed
K - complex values of autistic children with asymmetry or no asymmetry in cortical AMT uptake followed different developmental patterns , compared to that of a control group of non - autistic children . - pubmed
Five - year follow - up of patients with epidemic glomerulonephritis due to Streptococcus zooepidemicus . - pubmed
BACKGROUND : In 1998 there was a large outbreak of acute glomerulonephritis in Nova Serrana , Brazil , caused by group C Streptococcus zooepidemicus . - pubmed
Patients with reduced creatinine clearance were older than those without reduced renal function ( 54+/-15 vs 34+/-12 years , P<0.001 ) . - pubmed
CONCLUSIONS : After a mean time of 5.4 years , a relatively high proportion of patients with epidemic poststreptococcal glomerulonephritis due to S.zooepidemicus present hypertension , reduced renal function and increased microalbuminuria . - pubmed
Determination of these SNPs in ( future ) transplant recipients has the potential to identify individuals who are at risk of under - immunosuppression or the development of adverse drug reactions . - pubmed
Formalin fixed paraffin embedded tumour samples of 10 patients and adjacent non - malignant controls were analysed by radioactive labelled riboprobe in situ hybridisation ( isH ) and immunohistochemistry . - pubmed
The results also imply the existence of a cumulative exposure time or dose threshold for alcohol if promoting effects of cessation are to be seen on rat hepatocarcinogenesis . - pubmed
Women completed tests of memory , learning , and executive functioning , and hot flush and sleep assessments at baseline and study end . - pubmed
Facial paralysis may occur as a complication of central nervous system leukemias in children , but it is rarely a presenting symptom . - pubmed
This report describes an 8 - month - old child who presented with peripheral facial palsy , failure to thrive , anemia , and otitis media . - pubmed
This case should alert physicians to consider hematologic malignancies in children with facial paralysis . - pubmed
Here , we report on the results of 3 years of pamidronate treatment in 10 children and adolescents with OI type VI ( age range 0.8 to 14.5 years , three girls ) . - pubmed
Our results suggest that 3 years of intravenous pamidronate therapy led to improvements in bone mineral mass , gross motor function , muscle force and fracture incidence in patients with OI type VI . - pubmed
1034 children ( 91.8 % ) were dentally examined to assess their normative needs for 6 types of treatment ( dental caries , traumatic dental injuries , enamel defects , periodontal , orthodontic and prosthodontic treatment ) . - pubmed
Orf is a parapoxvirus infection of sheep and goats that causes blistering lesions on the lips , nostrils , udders or toes of affected animals . - pubmed
The 80 % aqueous acetone extracts from the fruit ( 50 mg / kg / d ) and seeds ( 12.5 and 25 mg / kg / d ) of Rosa canina L. , but not from the pericarps , were found to show substantial inhibitory effect on the gain of body weight and/or weight of visceral fat without affecting food intake in mice for 2 weeks after administration of the extracts . - pubmed
With regard to the active constituents , the principal constituent , trans - tiliroside ( 0.1 - 10 mg / kg / d ) , potently inhibited the gain of body weight , especially visceral fat weight , and significantly reduced blood glucose levels after glucose loading ( 1 g / kg , ip ) in mice . - pubmed
We describe the case of a patient with neurofibromatosis type 1 ( NF1 ) complicated by severe pulmonary aterial hypertension ( PAH ) ; only seven cases have been reported on this association so far , and PAH seems to be related to the vascular involvement of neurofibromatosis . - pubmed
On the basis of histological findings and of the results of genetic study we believe that PAH was a complication of NF1 in our patient and we suggest to screen patients with NF1 for the presence of PAH by means of trans - thoracic echocardiogram . - pubmed
Evaluation of tongue pressure on the inferior dental arch in patients with mandibular prognathism . - pubmed
UNLABELLED : The aim of the present study was to find out whether there is a difference between the force exerted by the tongue ( pressure ) in patients with mandibular prognathism and healthy controls and to determine the difference in tongue pressure on the inferior dental arch in patients with mandibular prognathism before and after mandibular setback . - pubmed
MATERIAL AND METHODS : Patients with mandibular prognathism were compared with healthy controls and data on tongue pressure were collected . - pubmed
RESULTS : Tongue pressure on the inferior dental arch in patients with mandibular prognathism ranged from 1.98 N to 12.26 N ( mean 5.356 N ) . - pubmed
Tongue pressure in the control group ranged from 2.36 N to 16.9 N ( mean 6.56 N ) , with most of the values ranging from 4.02 N to 7.84 N. CONCLUSIONS : Tongue pressure on the inferior dental arch is reduced in patients with mandibular prognathism . - pubmed
METHODS : Subjects were 230 healthy volunteers , 18 to 30 years of age with no history of alcohol or drug dependence . - pubmed
The epidermis , the outer layer of the skin composed of keratinocytes , is a stratified epithelium that functions as a barrier to protect the organism from dehydration and external insults . - pubmed
This paper reports a case of coccidioidal pericarditis diagnosed by an in - house Coccidioides posadasii antigen and confirmed with mycological and molecular methods . - pubmed
Direct thrombin inhibitors are commonly used anticoagulants in patients with known or suspected heparin - induced thrombocytopenia ( HIT ) . - pubmed
We describe a 26 - year - old pregnant woman with portal vein thrombosis and thrombocytopenia treated with argatroban for possible HIT during her last trimester . - pubmed
Even though the cause of this patient 's thrombocytopenia was later determined to be idiopathic thrombocytopenic purpura , this is an important case that adds to the literature on use of argatroban during pregnancy . - pubmed
[ Yakon tea induced hepatitis in a patient with alcoholic liver cirrhosis ] . - pubmed
To test this hypothesis , we analyzed sterol esters in plasma and tissues in patients having non - cholesterol sterols ( sitosterolemia and Smith - Lemli - Opitz syndrome ) . - pubmed
Relationship between postoperative infectious complications and glycemic control for diabetic patients in an orthopedic hospital in Kuwait . - pubmed
OBJECTIVE : To study the relationship between postoperative infectious complications and glycemic control for diabetic patients in an orthopedic hospital in Kuwait . - pubmed
RESULTS : Of 318 diabetic patients who underwent surgical operations , 90 ( 28.3 % ) developed postoperative complications ; HbA(1c ) & lt;7 % was significantly associated with decreased infectious complications with an adjusted odds ratio of 2.51 ( 95 % confidence interval , 1.20 - 2.89 ) . - pubmed
Regarding types of complications , urinary tract infectious complications were significantly higher among those patients with HbA(1c ) & gt ; or = 7 % ( p & lt ; 0.0001 ) , while other complications ( SSI , lower respiratory tract infection and sepsis ) showed nonsignificant differences ( p & gt ; 0.05 ) . - pubmed
Prophylaxis by antibiotics with preoperative patient preparation , proficient surgical technique and postoperative wound care is recommended for uncontrolled diabetics subjected to surgery . - pubmed
METHOD : Three patients with PLA were identified from the ward registion files and were retrospectively reviewed . - pubmed
Two patients were diagnosed with hepatocellular carcinoma and one with metastatic cholangiocarcinoma . - pubmed
Two patients were subjected to biopsies showing features of inflammatory pseudotumor before a diagnosis of hepatocellular carcinoma . - pubmed
CONCLUSIONS : This series of cases highlights the importance of considering underlying hepatobiliary malignancies in patients with PLA and a close follow - up necessary for non - resolving hepatic lesions . - pubmed
Characteristic mutations in hepatitis C virus core gene related to the occurrence of hepatocellular carcinoma . - pubmed
Previous studies have shown that there might be some characteristic mutations in the core region of HCV related to HCC . - pubmed
Whole genome survey of copy number variation in the spontaneously hypertensive rat : relationship to quantitative trait loci , gene expression , and blood pressure . - pubmed
The aim of our study was to determine whether copy number variants ( CNVs ) exist between the spontaneously hypertensive rat ( SHR ) and its control strain , the Wistar - Kyoto rat , whether these map to quantitative trait loci in the rat and whether CNVs associate with gene expression or blood pressure differences between the 2 strains . - pubmed
Acute ST - elevation myocardial infarction in young patients : 15 years of experience in a single center . - pubmed
BACKGROUND : There have been few studies done regarding young patients with ST - elevation myocardial infarction ( STEMI ) . - pubmed
The purpose of this study was to investigate the clinical characteristics and coronary angiographic features in young patients with STEMI . - pubmed
METHODS : We collected data on 849 consecutive patients with STEMI from 1992 to 2006 . - pubmed
RESULTS : Young patients presented 11.6 % of all patients with STEMI . - pubmed
Because of an unpredicted and unavoidable shortage in global supplies of imiglucerase for Gaucher disease , we collected clinical and laboratory data from patients who were evaluated & lt;= 6months before drug withdrawal and then retested before / during reinstatement of therapy . - pubmed
Although we no longer think that drug vacations should be considered as a form of maintenance for patients requiring enzyme therapy for Gaucher disease , but if necessary - for compelling personal reasons - one may be reassured that a short - term drug interruption is not likely to lead to irreversible complications or return to baseline values of critical clinical parameters . - pubmed
The Charles Bonnet syndrome ( CBS ) is a condition associated with complex visual hallucinations occurring in the elderly in patients with visual impairment and normal mental health . - pubmed
Here , we report the case of a 78 - year - old woman who has a limited visual acuity with a CBS that we postulated to be in relationship to a vitamin B12 deficiency . - pubmed
Radiological techniques are important in evaluating patients with gastrointestinal bleeding . - pubmed
Scintigraphic , computed tomographic angiographic , and enterographic techniques are sensitive tools in identifying the source of bleeding and may be useful in identifying patients likely to have a benign course and in selecting patients for therapeutic intervention . - pubmed
With the refining developments in body imaging and related reconstructive techniques , it is likely that radiological interventions will play an expanding and critical role in evaluating patients with gastrointestinal hemorrhage in the future . - pubmed
Splenectomy following abdominal trauma is rare in children . - pubmed
We report two cases of children requiring splenectomy following severe blunt abdominal injury . - pubmed
We wish to highlight these radiological features of splenic avulsion as they can help to focus management decisions regarding the need / timing for a laparotomy following blunt abdominal trauma in children . - pubmed
We present a case of paraffinoma in a 64 - year - old woman , which occurred in the eyelid after endoscopic sinus surgery for chronic sinusitis . - pubmed
Rib metastases from a non - tonsillar squamous cell carcinoma in a dog . - pubmed
The dog presented with a history of a rapidly growing SCC of the right upper incisive region , which was confirmed by histopathology as a SCC . - pubmed
Although erectile dysfunction ( ED ) is a frequent complaint in patients with DM1 , it has not been investigated in great depth . - pubmed
Patients with hormonal evidence of interstitial failure had a larger CTG expansion ( p = 0.008 ) , longer disease duration ( p = 0.013 ) , higher grade of disease ( p = 0.004 ) and lower erectile function score ( p = 0.02 ) than eugonadic patients . - pubmed
Impotence occurred in 13/14 hypogonadic patients with interstitial failure and in 5/12 eugonadic patients ( p = 0.017 , OR = 18.2 ) . - pubmed
Recent studies present data on patient - reported outcomes and show that the benefit of suppression of joint damage progression is maintained over time . - pubmed
Many of these analogues had MIC & lt;= 0.25 mug / mL against quinolone - resistant MRSA strains . - pubmed
The MICs of these select ITQs versus a panel of clinical MRSA strains were determined , and the ITQs were found to have 8- to 16 - fold greater potency than linezolid . - pubmed
We compared patient outcomes following neoadjuvant or adjuvant systemic chemotherapy for cT2 - T4aN0 - N2M0 bladder cancer . - pubmed
METHODS : In a retrospective review of a single institutional database from 1988 through 2009 , we identified patients receiving neoadjuvant or adjuvant multiagent platinum - based systemic chemotherapy for locally advanced bladder cancer . - pubmed
With regard to the limited efficacy of currently available anti - dementia drugs it is crucial to investigate whether such treatments also provide clinically meaningful benefits to cognitively impaired older individuals . - pubmed
METHODS : We conducted a systematic review of randomized controlled trials evaluating cognition - focused interventions in participants with mild cognitive impairment or dementia . - pubmed
We describe a patient with multiple metachronous bone metastases from lower rectal cancer who was successfully treated with multimodal treatment including surgical resections and has shown 32 mo disease - free survival . - pubmed
Surgical resection of metastatic bone lesion(s ) from colorectal cancer may be a good treatment option in selected patients . - pubmed
Use of acupuncture therapy as a supplement to conventional medical treatments for acute ischaemic stroke patients in an academic medical centre in Korea . - pubmed
This study was conducted to estimate the usage rate of acupuncture as a supplemental treatment in acute ischaemic stroke patients and to identify factors associated with the choice to use this therapy . - pubmed
METHODS : Using the registry of stroke patients admitted to an academic medical centre in Korea , the use of acupuncture therapy was recorded and analysed , along with the patients ' socio - demographic characteristics , hospital access variables , risk factors for ischaemic stroke and clinical characteristics . - pubmed
After controlling for other significant factors , there was an approximately 3.4 - fold greater usage in patients with moderately severe strokes ( 95 % confidence interval ( CI)=2.5 - 4.6 ) and 4.1 - fold greater usage in patients with severe strokes ( 95 % CI=2.7 - 6.4 ) . - pubmed
CONCLUSIONS : The findings provide a better understanding of patients ' utilization of acupuncture therapy as a supplement to conventional medical treatments and of factors associated with the utilization of acupuncture in patients with acute ischemic stroke . - pubmed
Participants were interviewed and tested for HIV and STIs . - pubmed
METHODS : A total of 165 patients ( 104 with acute and 61 with chronic urticaria ) from a tertiary referral hospital were enrolled in this study . - pubmed
Morphological and immunohistochemical characterization of spontaneous thyroid gland neoplasms in guinea pigs ( Cavia porcellus ) . - pubmed
Reports of thyroid gland neoplasms in guinea pigs ( Cavia porcellus ) are rare , but thyroid tumors are among the most common neoplasms seen in cases submitted to Northwest ZooPath . - pubmed
This report describes the histological and immunohistochemical characteristics of thyroid neoplasms and lists the concurrent conditions found in guinea pig cases submitted to Northwest ZooPath during 1998 to 2008 . - pubmed
Of 526 guinea pig case submissions , 19 had thyroid neoplasms . - pubmed
Neoplasms were removed as an excisional biopsy from 7 guinea pigs , and 3 of these animals died within a few days after surgery . - pubmed
Research is needed to determine the appropriate modalities for antemortem diagnosis and treatment and whether thyroid disease plays a role in the pathogenesis of chronic degenerative diseases in guinea pigs . - pubmed
We currently use Mucor circinelloides as a model organism to develop strains able to produce new , more valuable , and with an increased content of carotenoids . - pubmed
Bronchiolitis associated with exposure to artificial butter flavoring in workers at a cookie factory in Brazil . - pubmed
OBJECTIVE : To report the cases of four patients with bronchiolitis caused by exposure to artificial butter flavoring at a cookie factory in Brazil . - pubmed
RESULTS : All four patients were young male nonsmokers and developed persistent airflow obstruction ( reduced FEV1 / FVC ratio and FEV1 at 25 - 44 % of predicted ) after 1 - 3 years of exposure to diacetyl , without the use of personal protective equipment , at a cookie factory . - pubmed
CONCLUSIONS : Bronchiolitis resulting from exposure to artificial flavoring agents should be included in the differential diagnosis of airflow obstruction in workers in Brazil . - pubmed
Identification and characterization of the functional toxboxes in the Vibrio cholerae cholera toxin promoter . - pubmed
METHODS : The study was conducted in patients of COPD in TB chest department of a medical college hospital . - pubmed
Human adipose - derived stromal / stem cells : a novel approach to inhibiting acute pancreatitis . - pubmed
Accumulated data suggest human adipose - derived stromal / stem cells would be a valuable tool for cell - based therapy for inflammatory disease , autoimmune disease , tissue repair , and ischemic insults by controlling cell death , immune response , inflammation , and tissue regeneration . - pubmed
Thus , it is reasonable to hypothesize that human adipose - derived stromal / stem cells would be a novel approach to inhibiting inflammation and reducing acute pancreatitis . - pubmed
Dahl ( S x R ) rat congenic strain analysis confirms and defines a chromosome 17 spatial navigation quantitative trait locus to & lt;10 Mbp . - pubmed
METHODS : A model was developed using NONMEM ( ) version 7.2 based on RBC data obtained from 48 patients with RA receiving once - weekly low - dose MTX treatment . - pubmed
BACKGROUND : Since sedatives are often administered to immune - compromised and critically ill patients , our understanding of immunomodulation by sedation will be critical . - pubmed
CONCLUSIONS : Dexmedetomidine can have beneficial effect on preoperative or postoperative inflammatory bowel disease patients in intensive care units by down - regulating inflammatory immune response not only in systemic circulation but also in tissue - specific manner . - pubmed
Timely anticoagulation introduction in asymptomatic patients may impact on the stroke rate . - pubmed
According to the results of repeated Monte Carlo simulations based on a real population of 166 patients , daily monitoring may reduce the 2 - year stroke risk by 9 - 18 % with an absolute reduction of 0.2 - 0.6 % , compared with conventional inter - visit intervals of 6 - 12 months . - pubmed
Whereas imaging studies commonly show hippocampal activation during short - delay memory tasks , evidence from amnesic patients with MTL lesions is mixed . - pubmed
MATERIAL AND METHOD : One hundred and twenty consecutive patients with steatosis or normal liver , assessed by ultrasound by the same expert , were enrolled . - pubmed
[ Clinical features and treatment of acute clenbuterol poisoning in children ] . - pubmed
OBJECTIVE : To study clinical features , treatment and curative effects in children with acute clenbuterol poisoning , in order to provide a basis for early diagnosis and treatment . - pubmed
METHODS : Clinical data of 28 hospitalized children with acute clenbuterol poisoning in April 2011 were retrospectively studied . - pubmed
Vomiting , palpitations and limb shaking were found as main clinical manifestations in the patients . - pubmed
CONCLUSIONS : Acute clenbuterol poisoning is characterized by vomiting , palpitations , limb shaking , hypokalemia , lactic acidosis and tachycardia in children . - pubmed
Phenotypic and genotypic coefficients of variation , heritability , and genetic advance were estimated for : time to vine emergence , leaf size , leaf virus infection , plant leafiness , shoot height , vine dry weight , number of tubers per hill and tuber yield per hill in white yam ( Dioscorea rotundata Poir . ) - pubmed
Improving cytopenia with splenic artery embolization in a patient with paroxysmal nocturnal hemoglobinuria on eculizumab . - pubmed
We describe a patient under treatment with the anti - complement antibody eculizumab who developed pancytopenia , requiring blood transfusions , due to massive splenomegaly . - pubmed
BACKGROUND : Endoscopic collateral ventilation assessment ( ECVA ) can be used to select patients suffering from emphysema for application of valves to achieve a reduction of lung volume . - pubmed
METHODS : Patients with severe chronic obstructive pulmonary disease ( COPD ) underwent examination for a possible reduction of lung volume . - pubmed
RESULTS : Of a tested 310 emphysema patients , 17 met criteria allowing ECVA ; 10 of 17 proved eligible for valve application . - pubmed
CONCLUSIONS : Only a small portion of patients with progressive emphysema of the lung seem suitable for endoscopic reduction of lung volume by application of valves . - pubmed
Hypothesizing a continuum between emesis gravidarum and HG , we investigated androgen concentrations in women with HG . - pubmed
STUDY DESIGN : In a case - control study , 32 women hospitalized for HG were compared with 29 control women scheduled for elective surgical abortion . - pubmed
CONCLUSION : Steroid hormone homeostasis may be altered in women with HG . - pubmed
Impact of acellular mucin pools on survival in patients with complete pathological response to neoadjuvant treatment in rectal cancer . - pubmed
The objective of this study was to determine impact of acellular mucin pools on disease free and overall survival in patients with complete pathological response to neoadjuvant chemoradiotherapy in rectal cancer . - pubmed
METHODS : One hundred and seventy two patients received neoadjuvant chemoradiotherapy for rectal cancer and underwent surgery . - pubmed
BACKGROUND : Guidelines now recommend high - intensity statins in all individuals with atherosclerotic cardiovascular disease . - pubmed
METHODS : SATURN ( Study of Coronary Atheroma by Intravascular Ultrasound : Effect of Rosuvastatin Versus Atorvastatin ) employed serial intravascular ultrasound measures of coronary atheroma volume in patients treated with rosuvastatin 40 mg or atorvastatin 80 mg for 24 months . - pubmed
CONCLUSIONS : Women with coronary disease demonstrate greater coronary atheroma regression than men when empirically prescribed guideline - driven potent statin therapy . - pubmed
Glioblastoma multiforme ( GBM ) is the prevalent and most fatal brain tumor in adults . - pubmed
We evaluated the contribution of headache chronicity to QOL in relation to clinical , psychiatric , and psychosocial variables in patients with migraine . - pubmed
RESULTS : Among 251 eligible patients , 183 ( 72.9 % ) had episodic migraine ( EM ) and 68 ( 27.1 % ) had chronic migraine ( CM ) . - pubmed
Patients with CM had more serious clinical , psychiatric , and poor QOL than did patients with EM . - pubmed
Triple immunosuppressive therapy in steroid - resistant nephrotic syndrome children with tacrolimus resistance or tacrolimus sensitivity but frequently relapsing . - pubmed
METHODS : Eighteen consecutive children with steroid- and tacrolimus ( TAC)-resistant ( n = 10 ) or TAC - sensitive but frequent relapsing nephrotic syndrome ( n = 8) were randomly recruited in the present study . - pubmed
RESULTS : Compared with previous double - combination therapy of prednisone ( Pre ) and TAC , the short - term remission rate in all 18 patients was significantly improved after the triple - combination therapy , while the frequent relapse rate in the following 12 months was also significantly decreased . - pubmed
CONCLUSION : Triple - combination therapy with Pre + TAC + CTX / MMF / LEF is effective for short - term response and 1 year remission , without significant additional side - effects seen in children with steroid - resistant and tacrolimus - resistant or tacrolimus - sensitive but frequently relapsing nephrotic syndrome . - pubmed
Classical swine fever ( CSF ) caused by CSF virus ( CSFV ) is a highly contagious and devastating disease that affects the pig industry worldwide . - pubmed
All animals were challenged with CSFV C - strain at 4 weeks and then boosted with the same dose . - pubmed
The rabbits inoculated with CSFV-1.1E2 and CSFV-1.1 + 2.1E2 received complete protection against CSFV C - strain . - pubmed
These results demonstrate that CSFV-1.1E2 and CSFV-1.1 + 2.1E2 not only elicit humoral and cell - mediated immune responses but also confer complete protection against CSFV C - strain in rabbits . - pubmed
PRESENTATION OF CASE : A 37 - year - old woman complained of painless and reducible swelling in her left groin , and referred to our hospital for surgical management against left inguinal hernia with the incarcerated ovary . - pubmed
The accurate diagnosis of an inguinal hydrocele in a female is seldom made . - pubmed
CONCLUSION : Laparoscopic diagnosis and TEP treatment offers a useful alternative in selected patients with hydrocele of the canal of Nuck . - pubmed
In this respect , it is known that the patients who underwent radical nephrectomy due to renal tumor are under high risk of chronic kidney disease ( CKD ) in the long term . - pubmed
70 patients who underwent donor nephrectomy as renal donors and 130 patients who underwent radical nephrectomy due to renal tumor were studied . - pubmed
Peripheral nerve injury is a serious problem affecting significantly patients ' life . - pubmed
Autografts are the " gold standard " used to repair the injury gap , however , only 50 % of patients fully recover from the trauma . - pubmed
METHODS : A single - institution retrospective study was performed with 331 patients who underwent radical resection of thymoma between 1991 and 2012 . - pubmed
Relapse occurred in 23 patients with the pleura ( 14 ) and tumor bed ( 6 ) as the most common sites of recurrence . - pubmed
According to the definitions of the International Thymic Malignancy Interest Group , 10 ( 43.5 % ) patients had local relapse , 15 ( 65.2 % ) had regional relapse , 10 ( 43.5 % ) had distant relapse . - pubmed
The recurrence - free survival rates in patients with tumor size & gt;=8 cm were worse than those of patients with tumor size & lt;8 cm ( P=0.007 ) . - pubmed
Mixed Infections and Rifampin Heteroresistance among Mycobacterium tuberculosis Clinical Isolates . - pubmed
Mixed infections and heteroresistance of Mycobacterium tuberculosis contribute to the difficulty of diagnosis , treatment , and control of tuberculosis . - pubmed
We aimed to assess 1 - year prognosis in patients experiencing silent AF in AMI . - pubmed
METHODS : All consecutive patients with AMI who were prospectively analysed by CEM during the first 48 h after admission and who survived at hospital discharge were included . - pubmed
Silent AF was defined as asymptomatic episodes lasting at least 30 s. Patients were followed up at 1 year for cardiovascular ( CV ) outcomes . - pubmed
RESULTS : Among the 737 patients analysed , 106 ( 14 % ) developed silent AF and 32 ( 4 % ) symptomatic AF . - pubmed
Compared with the no - AF group , patients with silent AF were markedly older ( 79 vs 62 years , p<0.001 ) , more frequently hypertensive ( 71 % vs 49 % , p<0.001 ) and less likely to be smokers ( 23 % vs 37 % , p<0.001 ) . - pubmed
However , a history of stroke or AF was less frequent in silent AF than in symptomatic - AF patients ( 10 % vs 25 % and 10 % vs 38 % , respectively ) . - pubmed
Systematic screening and specific management should be investigated in order to improve outcomes of patients after AMI . - pubmed
METHODS : With Institutional Review Board approval , 4 septic and 6 nonseptic extremely low birth weight patients were enrolled . - pubmed
The aim of this study was to assess the impact of CT - assessed sarcopenia on short- and long - term outcomes in patients undergoing surgical resection of gastrointestinal and hepatopancreatobiliary malignancies . - pubmed
WML were present in 103 ( 52.6 % ) individuals . - pubmed
According to this classification , HBV carriers showing acute hepatitis exacerbation were divided into 3 subgroups ; asymptomatic or inactive HBV carriers without drug exposure , asymptomatic or inactive HBV carriers developing HBV reactivation during and after immunosuppressive therapies and/or antineoplastic chemotherapies and those with previously resolved HBV infection showing iatrogenic HBV reactivation . - pubmed
In an annual nationwide survey in 2013 , however , a patient with previously resolved HBV infection was enrolled , in whom LOHF developed as a result of HBV reactivation despite in the absence of immunosuppressive therapies and/or antineoplastic chemotherapies . - pubmed
Thus , the study group revised the classification criteria in 2015 ; HBV carriers developing acute hepatitis exacerbation were classified into asymptomatic or inactive HBV carriers and patients with previously resolved HBV infection , and both groups were further sub - classified into those receiving immunosuppressive therapies and/or antineoplastic chemotherapies and those without such drugs exposure . - pubmed
Evaluation of the potential for QTc prolongation in patients with solid tumors receiving nivolumab . - pubmed
Role of gefitinib in the targeted treatment of non - small - cell lung cancer in Chinese patients . - pubmed
This paper reviews its role in the targeted treatment of NSCLC in Chinese patients . - pubmed
A total of 20,922 participants ( 53 % women ; mean age 58 + - 9 years ) were included of whom 1101 developed heart failure during the follow up ( mean 12.5 + - 2.7 years , total person years 262,291 years ) . - pubmed
Men experienced significant improvement in urinary flow rate , postvoid residual urine , and OAB symptoms reported on the OABSS . - pubmed
Of the 28/42 men with preoperative , clinically significant OAB ( ie , OABSS & gt;= 8) , 25/28 reported a 54.2 % ( 0%-100 % ) median reduction in OABSS , with only 1 patient reporting worsening of symptoms following surgery . - pubmed
Those men with the highest preoperative OABSS experienced the greatest improvement in OAB symptoms postoperatively . - pubmed
However , the function of lncRNAs in human gastric cancer remains largely unknown . - pubmed
PURPOSE : To compare visual acuity ( VA ) , contrast sensitivity , stereopsis , and subjective visual performance of Acuvue Oasys for Presbyopia ( AOP ) , Air Optix Aqua Multifocal ( AOMF ) , and Air Optix Aqua Single Vision ( AOSV ) lenses in patients with presbyopia . - pubmed
Twenty patients with mild presbyopia ( add & lt;=+1.25 D ) and 22 with moderate / severe presbyopia ( add & gt;=+1.50 D ) who wore lenses bilaterally for 1 h , with a minimum overnight washout period between the use of each lens . - pubmed
CONCLUSIONS : Further development of multifocal lenses is required before significant advantages of multifocal lenses over single vision lens are observed in patients with presbyopia . - pubmed
DT97 was evaluated in the NCI-60 panel of human cancer cell types and anticancer activity was greatest against MM , leukemia and lymphoma cells . - pubmed
Co - treatment with DT97 and bortezomib synergistically induced apoptosis in MM patient cells and overcame bortezomib - resistance . - pubmed
Co - treatment with bortezomib and DT97 reduced the growth of myeloma xenotransplants in murine models and prolonged host survival . - pubmed
Analysis of oral yeast microflora in patients with oral squamous cell carcinoma . - pubmed
BACKGROUND : Oral squamous cell carcinoma ( OSCC ) is the most common form of oral cancer , in this study , the association between OSCC and oral yeast carriage was investigated . - pubmed
FINDINGS : 20 patients having OSCC as well as 40 healthy controls were tested for the presence of yeasts in the oral cavity . - pubmed
We found that the level of oral yeast carriage was significantly higher in patients with OSCC that was accompanied by a higher diversity of yeasts in the oral cavity of these patients . - pubmed
BACKGROUND : The ability to identify high risk head and neck cancer ( HNC ) patients with disseminated disease prior to presenting with clinically detectable metastases holds remarkable potential . - pubmed
However , the clinical significance of CTCs in head and neck cancer patients has yet to be determined . - pubmed
METHODS : The aim of this study was to screen advanced stage HNC patients by the CellSearch platform and utilise two other epitope - independent approaches , ScreenCell ( microfiltration device ) and RosetteSep ( negative enrichment ) , to determine how a shift to such methodologies would enable CTC enrichment and detection . - pubmed
BACKGROUND : The human body has an extensive capacity to regenerate bone tissue after trauma . - pubmed
Therefore , the aim of the present study was to assess the pool and biological functions of human mesenchymal stromal cells ( hMSCs ) isolated from different bone marrow locations of the lower limbs and to identify novel strategies to prime the cells prior to their use in bone fracture healing . - pubmed
White - nose syndrome is an invasive bat disease caused by the fungus Pseudogymnoascus destructans , which has killed more than six million bats in the last 7 years . - pubmed
Our results suggest that bats in western North America caves possess novel bacterial microbiota with the potential to inhibit P. destructansIMPORTANCE This study reports the largest collection of actinobacteria from bats with activity against Pseudogymnoascus destructans , the fungal causative agent of white - nose syndrome . - pubmed
These cells were inoculated in the mammary fat pad of female severe compromised immunodeficient mice , which subsequently formed xenograft tumors that metastasized to the lungs . - pubmed
Our data was compared to several gene datasets of various subtypes , classes , and grades of human breast cancers . - pubmed
We demonstrated that the genes and pathways altered in the transgenic cell line and metastatic animal models parallel many of the dysregulated gene pathways observed in human breast cancers . - pubmed
pylori - positive dyspeptic patients were enrolled , either naive or with previous failure treatment . - pubmed
They were mild in all cases except in four , who discontinued the study due to diarrhea ( three patients ) and diffuse urticarial rush ( one patient ) . - pubmed
One Health is an emerging concept that stresses the linkages between human , animal , and environmental health , as well as the need for interdisciplinary communication and collaboration to address health issues including emerging zoonotic diseases , climate change impacts , and the human - animal bond . - pubmed
Data support further development of FXaI16L for patients with acute hemorrhagic conditions . - pubmed
The safety profile , pharmacokinetics and pharmacodynamics observed in this clinical trial support the further development of FXaI16L for hemostatic treatment in individuals with acute hemorrhagic conditions . - pubmed
Clinical characteristics and surgical treatment of spinal paraganglioma : A case series of 18 patients . - pubmed
METHODS : The clinical and follow - up data of 18 patients who were diagnosed of spinal paraganglioma and treated with surgeries in our hospitals from 2003 to 2014 were retrospectively analyzed . - pubmed
RESULT : A total of fourteen patients radiographed of intra - spinal tumor underwent extra - capsular tumor resection . - pubmed
Of five patients with obvious vertebral bone damage , four cases underwent piecemeal resection , and the left one with sacral tumor underwent en bloc tumor excision . - pubmed
METHODS : A retrospective analysis of all 58 patients with MRTK from Austria , Switzerland , and Germany treated in the framework of consecutive , prospective renal / rhabdoid tumor studies SIOP9 / GPO , SIOP93 - 01 / GPOH ( where SIOP is International Society of Pediatric Oncology and GPOH is German Society of Pediatric Oncology and Hematology ) , SIOP2001 / GPOH , and European Rhabdoid Tumor Registry from 1991 to 2014 . - pubmed
Thirty - seven ( 64 % ) patients achieved a complete remission , 17 ( 29 % ) relapsed , 34 ( 59 % ) died of disease progression , and two ( 3 % ) died of treatment - related complication . - pubmed
CONCLUSION : Our retrospective analysis suggests comparable outcomes for patients with and without HDSCT , if adjusted for early disease progression . - pubmed
Observations : An 81 - year - old male presented with decreased vision in the left eye due to a full - thickness macular hole secondary to vitreomacular traction . - pubmed
Tacrolimus and Mycophenolate Mofetil as Second - Line Therapies for Pediatric Patients with Autoimmune Hepatitis . - pubmed
BACKGROUND : We studied the efficacy and safety of mycophenolate mofetil ( MMF ) and tacrolimus as second - line therapy in pediatric patients with autoimmune hepatitis ( AIH ) who were intolerant or non - responders to standard therapy ( corticosteroid and azathioprine ) . - pubmed
CONCLUSIONS : Long - term therapy with MMF or tacrolimus was generally well tolerated by pediatric patients with AIH . - pubmed
In vivo therapeutic efficacies of gemcitabine and rad001 alone and their combination were further evaluated using a xenograft mouse model and a chemically induced orthotopic cholangiocarcinoma rat model . - pubmed
In a chemically induced cholangiocarcinoma - afflicted rat model , the gemcitabine plus rad001 treatment suppressed tumor glycolysis as measured by 18F - fludeoxyglucose micro - positron emission tomography . - pubmed
Elevated extracellular potassium prior to muscle contraction reduces onset and steady - state exercise hyperemia in humans . - pubmed
Persisters have been linked to recalcitrant infections caused by numerous bacterial pathogens , including Pseudomonas aeruginosa A classic example is the incurable infection of the airways for patients with cystic fibrosis . - pubmed
However , less is known about EBV 's interaction with T cells and its association with T cell lymphoma . - pubmed
Because , the co - presence of EBV infection with malaria is a well - known aetiology of lymphoma , EBV - early RNA ( EBER ) transcripts were investigated in paraffin - embedded tissue samples and found to be positive in macrophage - like histiocytes . - pubmed
This case emphasizes the clinical importance of EBV monitoring in T - LGL patients with skin involvement . - pubmed
Postural Orthostatic Tachycardia in a Patient with Type 2 Diabetes with Diabetic Neuropathy . - pubmed
A 24 - year - old Japanese man with type 2 diabetes mellitus and diabetic neuropathy was admitted to our ward to evaluate the cause of orthostatic intolerance . - pubmed
The relative sympathetic hyperactivity in the present patient with diabetic neuropathy seemed to be related to POTS . - pubmed
STUDY OBJECTIVE : To evaluate the feasibility , effectiveness , and reproductive outcome of hysteroscopic management using the Hysteroscopy Endo Operative system ( HEOS ) in patients with diffuse uterine leiomyomatosis ( DUL ) . - pubmed
Two patients had mild synechia after the first hysteroscopic surgery . - pubmed
One patient suffered a miscarriage in the second trimester ( live birth rate , 75 % ) . - pubmed
Importantly , treatment of adult mice with the established disease also reduced ICH . - pubmed
Anti - proliferative activity of Origanum vulgare inhibited lipogenesis and induced mitochondrial mediated apoptosis in human stomach cancer cell lines . - pubmed
In our present study , we have identified the bio - active principles of oregano essential oil ( EO ) and evaluated its apoptotic effects against human stomach cancer cell lines ( AGS ) . - pubmed
The present study finds rationale to use the oregano EO for stomach cancer treatments in traditional medicinal practice . - pubmed
Considering that hepatoblastoma develops in infants and children and aflatoxin M1 ( AFM1 ) , the aflatoxin B1 ( AFB1 ) hydroxylated metabolite , can be present in mothers ' milk and in marketed milk products , in this study we decided to test the effects of AFM1 on a hepatoblastoma cell line ( HepG2 ) . - pubmed
Recently , several studies have shown that morbidity and quality of life in adolescent and adult patients with 21 - OHD are impaired by obesity , hypertension , diabetes mellitus , impaired glucose tolerance , dyslipidemia , and osteoporosis . - pubmed
The tagging single nucleotide polymorphisms were genotyped using the TaqMan Allelic Discrimination assay in a total of 468 subjects ( 265 KD patients and 203 controls ) . - pubmed
Methodological questions regarding focused assessment sonography for trauma comparison with computed tomography in dogs . - pubmed
However , the patient subsequently developed multiple organ failure and died in April 2018 , approximately 6 months after the initial discovery of the mass in his neck . - pubmed
Purpose : For chronic inflammatory demyelinating polyneuropathy ( CIDP ) patients , each branded intravenous immunoglobulin ( IVIG ) treatment differs in production processes , virus elimination , formulation , and composition . - pubmed
Patients and methods : Two independent analytic teams retrospectively evaluated IVIG treatment - naive patients with an ICD diagnosis code for CIDP . - pubmed
Chronic pain is a major health - care problem worldwide , affecting more than one out of five adults in Europe . - pubmed
A 64 - year - old man with gastrointestinal stromal tumor of the small intestine discontinued adjuvant imatinib because of interstitial pneumonia . - pubmed
RESULTS : Cervical magnetic resonance imaging ( MRI ) revealed spinal cord edema in 9 patients and suspected hemorrhage or contusion in 7 cases . - pubmed
CASE REPORT A 76 - year - old male patient with a 4 - year history of reducible left inguinal hernia complained of abdominal pain for 2 h before admission . - pubmed
The present case report suggests that clinical and radiological awareness are very important for accurate diagnosis and management in patients with reduction en - masse of an inguinal hernia . - pubmed
Frequency of MRI changes suggestive of axial spondyloarthritis in the axial skeleton in a large population - based cohort of individuals aged < 45 years . - pubmed
Immune checkpoint inhibitors therapy in older patients ( > = 70 years ) with metastatic melanoma : a multicentre study . - pubmed
Aim : To analyse the efficacy and safety of immunotherapy with checkpoint inhibitors in older patients ( > = 70 years ) with metastatic melanoma . - pubmed
Neonates and immunosuppressed / immunocompromised pediatric patients are at high risk of invasive fungal diseases . - pubmed
In all patients , intra- and postoperative complications as well as the overall treatment outcome were recorded . - pubmed
Postoperative complications were found in 6 patients in group A and in one patient in group B. Analyzing risk factors for these complications , the highest OR ( 6.72 with p = 0.085 in univariate analysis ; 12.81 with p = 0.052 in multivariate analysis ) was found for the type of procedure ( group A / group B ) . - pubmed
All patients had complete mucosal coverage without any signs of antiresorptive agent - related osteonecrosis of the jaw at the final control examination 90 days postoperatively . - pubmed
CONCLUSION : Based on the results of this study , the use of PRF can be recommended as a preventive measure in patients requiring tooth extractions while being under antiresorptive therapy for osteoporosis . - pubmed
Chlorophenols ( CPs ) are known as a class of pollutants posing a great threat to the environment and human health because of their carcinogenesis and teratogenesis , and thus exploring convenient and efficient methods for their detection and identification becomes particularly important . - pubmed
Patients with mucosal melanoma may be offered the same therapies recommended for cutaneous melanoma . - pubmed
Incidence of New Primary Cutaneous Melanoma in Patients With Metastatic Melanoma Treated With Immune Checkpoint Inhibitors : A Single - Center Cohort Study . - pubmed
Objective : To determine the incidence of new CM in patients treated with ipilimumab , nivolumab , and/or pembrolizumab for metastatic melanoma . - pubmed
Design , Setting , and Participants : Single - center , retrospective , observational cohort study using an institutional database to identify patients diagnosed with melanoma at a tertiary care cancer hospital in New York , New York . - pubmed
Patients who developed a new CM were more likely to have a family history of melanoma ( 23.8 % vs 16.3 % , P = .02 ) . - pubmed
Conclusions and Relevance : Patients treated with ICI therapy for metastatic melanoma remain at risk for the development of new CM . - pubmed
RESULTS : 326 studies were screened , and 30 studies reporting findings from 55,176 patients including 899 with stroke were included . - pubmed
The average age of patients who suffered from stroke as a complication of COVID-19 was 65.5 ( Range : 40.4 - 76.4 years ) . - pubmed
The average mortality of stroke in COVID-19 patients was 31.76 % ( 95 % CI : 17.77 % to 47.31 % ) . - pubmed
In COVID-19 patients , stroke was associated with older age , comorbidities , and severe illness . - pubmed
Objectives : The paper presents the reconstructive options of the lower eyelid region in patients who have benefited from the excision of basal cell carcinomas . - pubmed
Methods : The study was based on the clinical and evolutionary particularities analyzed in a series of cases , the patients benefiting from excision and reconstruction for the treatment of basal cell carcinomas located at the level of the orbital region . - pubmed
The aesthetic results were strongly influenced by the stage of the neoplasm , the final aspect being satisfactory for the patients included in the study . - pubmed
The resolution of gastritis and peptic ulcer appears to be linked with the eradication of H pylori . - pubmed
Consequently , strategies aiming at inhibition of the cholesterol glucosylation process have the potential to attenuate the potency of H pylori infection and abrogate H pylori immune evasion capabilities . - pubmed
In this work , we review the main roles of cholesterol glucosylation in H pylori and evaluate whether this mechanism can be targeted for the development of alternate methods for eradication of H pylori infection . - pubmed
We identified 92 patients who were diagnosed with sIBM , according to the 2011 ENMC or Griggs et al criteria . - pubmed
BACKGROUND : 5 - Hydroxy-4 - methoxycanthin-6 - one ( PQ - A ) is the main active compound in Ramulus et Folium Picrasmae , a Chinese herbal medicine commonly used in colitis treatment . - pubmed
Less severe course of COVID-19 is associated with elevated levels of antibodies against seasonal human coronaviruses OC43 and HKU1 ( HCoV OC43 , HCoV HKU1 ) . - pubmed
However , in the rats adrenalectomized on day 15 or 20 , the body weights were lower than in control rats . - pubmed
A delay in the time at which vaginal opening and the first oestrus occurred was found in rats adrenalectomized at 20 or 25 days of age ; however this delay was accompanied in these rats by a retardation in the gain in body weight . - pubmed
[ Human pulmonary diffusing capacity in combined exposure to hypokinesia and hypoxia ] . - pubmed
Seven women in spontaneous labor , were compared to 7 women in whom labor was induced . - pubmed
The inhibitory effect of the combination of antineoplaston A-10 injection with a small dose of cis - diamminedichloroplatinum on cell and tumor growth of human hepatocellular carcinoma . - pubmed
A human hepatocellular carcinoma cell line ( KIM-1 ) was used for the cell growth and transplanted tumor growth studies . - pubmed
In the tumor growth study , daily administration of Antineoplaston A-10 Injection 75 mg with once a week administration of 20 micrograms of CDDP for 5 weeks inhibited transplanted tumor growth in athymic mice after 33 days of treatment , while administration of 75 mg of A-10 Injection or 20 or 60 micrograms of CDDP alone showed no significant inhibition of tumor growth . - pubmed
Patients ( pts ) with essential hypertension normally exhibit a typical diurnal variation with a nocturnal blood - pressure ( BP ) decreased . - pubmed
[ Functional activity of polymorphonuclear leukocytes in isoprenaline - induced cardiomyopathy in rats ] . - pubmed
The article studies the dynamics of changes of the parameters of the functional activity using chemiluminescent and turbidimetric methods as well as blood plasma myocardium and liver homogenates in isoprenaline cardiomyopathy in rats . - pubmed
Mechanisms of pathogenesis of isoprenaline - induced cardiomyopathy in rats is being discussed . - pubmed
The bidirectional effects of shock on alcohol preference in rats . - pubmed
Rats that initially preferred alcohol decreased alcohol preference during shock days , whereas , rats that initially avoided alcohol increased alcohol preference during shock days . - pubmed
[ Drug abuse and HIV in the hospital ] . - pubmed
In addition , HIV-1 PCR and HIV-1 culture were compared in testing the PBMC of 59 HIV-1 antibody - positive and 20 HIV-1 antibody - negative hemophiliacs . - pubmed
In contrast , the sensitivities of serum HIV-1 antigen testing in AIDS patients and asymptomatic seropositive patients were 42 and 17 % , respectively . - pubmed
Our ability to directly demonstrate HIV-1 infection in all HIV-1 antibody - positive individuals provides definitive support that HIV-1 antibody positivity is associated with present HIV-1 infection . - pubmed
Conception : Retrospective analysis of patients ( pts ) admitted either to UCIM or UTIC - AC with the diagnosis of AMI receiving SK . - pubmed
In contrast to avian influenza virus genes , human influenza virus genes evolve rapidly under the selective pressure of antibody . - pubmed
The changes in histamine and prostaglandins ( PGE2 and PGF ) in carrageenan - induced acute inflammation were studied in 6 day old air pouches in mice . - pubmed
Argon laser therapy of endometriosis : a review of 92 consecutive patients . - pubmed
The conception rate , relief of pain , and safety of argon laser photocoagulation of endometriosis were evaluated in 92 patients . - pubmed
The release and metabolism of endogenous arachidonic acid ( AA ) in physiologically activated platelets obtained from 11 atopic patients with allergic rhinitis and/or asthma was compared to that of sex- and age - matched nonatopic controls . - pubmed
Mild hypnotics are often recommended for young children with sleep problems . - pubmed
This study assesses the efficacy of trimeprazine tartrate in 1 to 3 year old children with persistent and severe night waking in a double blind crossover trial with placebo . - pubmed
Treatment outcome and complications in patients treated for malignant epidural spinal cord compression ( SCC ) . - pubmed
Lipid synthesis ( 14 C - acetate incorporation ) in the isolated human sebaceous gland , the appendage - freed epidermis , the sebocyst ( steatocystoma ) and the wen ( keratinous cyst of skin ) . - pubmed
Unusual serological behavior of a strain of Cl . - pubmed
[ Acid - base equilibrium of the amniotic fluid in pregnant women with heart defects ] . - pubmed
Disturbances of pulmonary function in patients with fat embolism . - pubmed
In the 26 animals studied , proliferative GN of variable severity was induced , with mild disease in 5 animals , moderate proliferation in 15 and crescentic GN in 6 . - pubmed
Specific binding of 1,25 - dihydroxycholecalciferol in human medullary thyroid carcinoma . - pubmed
A specific 1,25 - dihydroxycholecalciferol - binding protein has been detected in high - salt cytosols prepared from human medullary thyroid carcinomas . - pubmed
The management of the diabetic patient with renal disease . - pubmed
The case is presented of a 36 - year - old woman with a plasma - cell granuloma arising in the fourth ventricle . - pubmed
Morphine sulfate inhibits bronchoconstriction in subjects with mild asthma whose responses are inhibited by atropine . - pubmed
To determine whether morphine sulfate alters the bronchoconstrictive response to inhalation of distilled water , we gave 13 subjects with mild asthma 0.15 mg / kg morphine sulfate or normal saline intravenously , after which they inhaled increasing volumes of nebulized distilled water from an ultrasonic nebulizer . - pubmed
In the majority of the patients , subjective symptoms were noted : fever , headache , chills , nausea , myalgias . - pubmed
Leucopenia and thrombopenia were seen in 11 out of 13 patients . - pubmed
Activity of two phase I drugs , homoharringtonine and tricyclic nucleotide , against surgical explants of human tumors in the 6 - day subrenal capsule assay . - pubmed
Clearance half - times were prolonged in patients with lupus erythematosus compared with those in normal controls ( p less than 0.0001 ) and longer in patients with renal disease than in those without ( p less than 0.025 ) . - pubmed
When matched for nonrenal activity , patients with nephritis had greater clearance dysfunction than their counterparts without renal disease . - pubmed
Tiaprofenic acid 200 mg three times a day was compared with indomethacin 25 mg three times a day in 36 patients suffering from osteoarthritis of the knee and hip . - pubmed
Schistosoma mansoni : biochemical changes during early stages of the infection . - pubmed
Controversies surround the practice of prescribing potassium for ambulatory hypertensive patients who are being treated with diuretics . - pubmed
A chart review was conducted in a family medicine group practice to examine habits of potassium monitoring and supplement prescribing for patients receiving diuretic therapy for control of hypertension . - pubmed
An 11.1 % incidence of femoral osteolysis ( 30 cases in 28 patients ) was identified in a series of 271 primary total knee arthroplasties . - pubmed
In the study population , statistically significant factors associated with femoral osteolysis included male gender ( P & lt ; .05 ) , younger age ( P & lt ; .05 ) , increased patient weight ( P & lt ; .05 ) , positive tibial osteolysis ( P & lt ; .001 ) , osteoarthritis ( P & lt ; .07 ) , and length of time in situ ( P & lt ; .001 ) . - pubmed
The influence of age on treatment choice and survival in 735 patients with renal carcinoma . - pubmed
OBJECTIVE : To determine whether age is related to treatment choice and survival in patients with renal carcinoma . - pubmed
PATIENTS AND METHODS : In this retrospective study 735 patients with renal carcinoma , diagnosed between 1982 and 1990 in one of the hospitals connected to the Rotterdam Cancer Registry , were evaluated with respect to treatment choice and survival . - pubmed
RESULTS : Nephrectomy was performed less often in elderly patients , both with and without distant metastases . - pubmed
For patients with tumours restricted to the kidney ( Robson stage 1 ) , corrected survival rates were 80 , 70 and 48 % respectively . - pubmed
CONCLUSION : Treatment choice and outcome in patients with renal carcinoma were affected by age . - pubmed
The antimutagenic activity Angelica archangelica L. water and alcohol extracts thio - tepa against mutagenicity was investigated by the micronucleus test in mouse bone marrow and peripheral blood cells . - pubmed
Injury to 51Cr - labeled bovine artery pulmonary endothelial ( BPAE ) cells was quantified by the release of 51Cr from BPAE cells incubated for 18 h with injury expressed as a cytotoxic index . - pubmed
METHODS : A comprehensive staff follow - up program for all blood exposures with known patient sources was initiated in 1989 , consisting of patient follow - up by the Infection Control Department ( risk assessment for hepatitis B virus [ HBV ] and [ HIV ] infection and obtaining of consent for HIV testing ) and staff follow - up by the Occupational Health Department . - pubmed
HIV and HBV screening was obtained for 67.9 % and 87.6 % of patients assessed as at low risk and 82.3 % and 92.2 % of those assessed as at high risk for infection , respectively . - pubmed
Impact of tumor extent and location on treatment outcome in patients with stage III non - small cell lung cancer treated with radiation therapy . - pubmed
The results of treatment of 141 patients with stage III non - small cell lung cancer ( NSCLC ) who received definitive radiation therapy at Gunma University Hospital between 1976 and 1989 were retrospectively analyzed . - pubmed
As for tumor location , the patients with primary tumors in the upper lobes or the superior segment of the lower lobes of the lung lived longer than those with primary tumors at any other site ( P = 0.032 ) . - pubmed
Patients with epidermoid carcinoma had a higher survival rate at 5 years than those with other histologic types ( 14 % vs 3 % , P = 0.074 ) . - pubmed
Among the patients with stage III NSCLC , those with stage IIIA epidermoid carcinoma in the upper lobe or the superior segment of the lower lobe of the lung were considered to be the most favorable candidates for definitive radiation therapy . - pubmed
We investigated how residual tumour burden after cytoreductive surgery was related to the occurrence of acute and delayed nausea and vomiting in 101 ovarian cancer patients receiving their first chemotherapy course . - pubmed
Patients with large compared with minimal TB had more delayed emesis , especially on days 2 - 7 . - pubmed
The aggravating effect associated with large residual TB was more evident in patients & gt ; or = 55 years . - pubmed
During the second week after the chemotherapy the occurrence of nausea was higher in patients & gt ; or = 55 years than in those & lt ; 55 years . - pubmed
This was seen primarily in patients with large residual TB . - pubmed
The course of spinal muscular atrophy ( SMA ) is not well established except for those patients whose age of onset is before 6 months and who achieve only " sit with support " as their maximum function ( Werdnig - Hoffmann disease or SMA I ) . - pubmed
A microdialysis study in spontaneously hypertensive rats . - pubmed
Two groups of eight spontaneously hypertensive ( SHR ) and normotensive Wistar - Kyoto ( WKY ) rats , aged 14 to 16 weeks , were studied . - pubmed
Both activities were present in the PF of subjects with or without endometriosis . - pubmed
Our results demonstrate that although the strains belonged to different clones of V. - pubmed
Selective hippocampal lesions yield nonspatial memory impairments in rhesus monkeys . - pubmed
Monkeys with removals of medial temporal lobe ( MTL ) structures are widely recognized as valid models of human global anterograde amnesia , a syndrome that arises consequent to damage to a finite set of brain structures situated in the medial temporal lobe and/or medial diencephalon . - pubmed
However , a comparison of memory deficits in human and nonhuman primates with MTL damage has presented a long - standing puzzle . - pubmed
Whereas amnesic patients are impaired in learning object discrimination problems , monkeys with MTL damage are typically not . - pubmed
If this analysis is correct , monkeys with MTL damage might be disadvantaged in learning to discriminate similar objects presented in different contexts . - pubmed
Monkeys with hippocampal lesions were impaired relative to controls in learning object discrimination problems of this type . - pubmed
These findings strongly support the idea that the difference in the effect on object memory of MTL damage in human and nonhuman primates is due to a difference in the opportunity to employ contextual cues rather than to a difference in the organization of memory . - pubmed
One patient was a 29 - year - old male who complained of posteromedial radiating knee pain . - pubmed
The schedule is active in patients with heavily pre - treated breast cancer , with responses in up to 53 % ( overall 29 % ) . - pubmed
At the Royal Marsden Hospital we have evaluated infusional 5 - FU 200 mg / m2 per day for up to 6 months in combination with 3 - weekly bolus epirubicin ( E ) 60 mg / m2 and cisplatin ( C ) 60 mg / m2 ( infusional ECF ) as pre - operative / neo - adjuvant treatment in 123 patients with operable breast cancer greater than 3 cm ( median 6 cm ) , initially in a phase II study of 50 patients and subsequently as part of a randomised phase III trial . - pubmed
These trials will determine whether encouraging phase II activity with continuous infusional chemotherapy translates eventually into real survival benefit for patients with early breast cancer . - pubmed
OBJECTIVE : To study the injury factors , pathogenic process and clinical features of delay two - phase multiple organ dysfunction syndrome ( MODS ) in severe burned patients and to replicate a standardized animal model that would accurately imitate the clinical features of MODS . - pubmed
METHODS : Forty - five human patients with burn size larger than 30 % total body surface area ( TBSA ) were analyzed . - pubmed
Thirty - two goats were randomly divided into three groups : 1 ) hemorrhagic shock ( group H , n = 6 ) ; 2 ) endotoxemia ( group E , n = 6 ) ; and 3 ) hemorrhagic shock plus endotoxemia ( group M , n = 20 ) . - pubmed
Two patients with burn extent reaching 100 % TBSA survived with only mild acute respiratory distress syndrome ( ARDS ) and renal dysfunction after comprehensive treatment of burn shock , including adequate fluid resuscitation , drugs to remove oxygen free radicals , rapid restoration of pHi , and early extensive excision of burn eschars . - pubmed
CONCLUSION : Both in human patients or animal experimentation , the typical delay two - phase MODS is shown to be produced by two successive insults in the forms of hypovolemic shock and sepsis . - pubmed
The purpose of this study was to examine whether vitamin E supplementation in humans would attenuate an increase of serum enzymes as an indirect marker of muscle damage following a sudden large increase in the running distance in a 6 - day running training or not . - pubmed
Styrene epoxidation of the strain PS-1206 was studied in different reaction time . - pubmed
Conversion was required in three patients secondary to bleeding or anatomical anomalies . - pubmed
METHODS : The mouse model of live fibrosis was established with the application of intragastric installations of carbon tetrachloride once every three days ; scanning electron microscope and computer image processing were used to detect the area and the distributive density of the peritoneal lymphatic stomata ; and the concentrations and NO in the serum were measured and analyzed in the experiment . - pubmed
PAGOD syndrome : eighth case and comparison to animal models of congenital vitamin A deficiency . - pubmed
The condition may resemble the malformation complex associated with developmental deficiency of vitamin A or retinoic acid , as described in animal models . - pubmed
Affected children may suffer profound developmental and cognitive impairment from exposure to high levels of BCAA and their associated neurotoxic metabolites . - pubmed
This approach results in a 75 % reduction of systemic toxin levels within 3 h. When compared to other reported modalities of therapy for symptomatic neonates with MSUD , this approach appears to be most efficacious . - pubmed
Use of cattle farm resources by badgers ( Meles meles ) and risk of bovine tuberculosis ( Mycobacterium bovis ) transmission to cattle . - pubmed
We conclude that exploitation by badgers of resources provided by cattle farms constitutes a potentially important mechanism for tuberculosis transmission from badgers to cattle . - pubmed
Assessment of cell type specific gene transfer of polyoma virus like particles presenting a tumor specific antibody Fv fragment . - pubmed
Cyanovirin - N ( CV - N ) is under development as a topical ( vaginal or rectal ) microbicide to prevent sexual transmission of human immunodeficiency virus ( HIV ) , and an economically feasible means for very large - scale production of the protein is an urgent priority . - pubmed
Chlamydia pneumoniae DNA has been detected in at least 40 % of all major arteries affected by atherosclerosis , but several other microorganisms have also been detected . - pubmed
These findings may have implications for antibiotic prophylaxis of coronary heart disease if directed solely at Chlamydia pneumoniae . - pubmed
Neonatal lesions in the amygdala or ventral hippocampus disrupt prepulse inhibition of the acoustic startle response ; implications for an animal model of neurodevelopmental disorders like schizophrenia . - pubmed
Schizophrenic patients show deficits in prepulse inhibition of the acoustic startle response . - pubmed
The animal model of neurodevelopmental disorders such as schizophrenia , as purported in earlier reports and the present study , is based on the assumption that damage to brain structures early in life ( on day 7 ) disrupts brain maturation of structures connected to the damaged areas , measurable by behavioural changes , whereas similar damage later in life ( on day 21 ) does not result in these behavioural changes . - pubmed
The effects of early postnatal lesions on prepulse inhibition and locomotor activity are in support of the animal model of neurodevelopmental disorders like schizophrenia . - pubmed
Renal transplantation offers the best renal replacement therapy for most children with end stage renal disease improving their potential for growth and nutrition , neurodevelopment and quality of life . - pubmed
Advances in organ retrieval and preservation , improved surgical techniques , newer immunosuppressive drugs and prevention and treatment of infections have significantly improved patient and graft survival . - pubmed
Of a study group of 1286 patients who were referred in early chronic - phase CML between 1981 - 2001 and who received therapies other than allogeneic SCT , 1093 patients had regular follow - up at the study institution . - pubmed
Patients with sudden blastic - phase disease were found to have more often low - risk features at the time of presentation , including low incidences of blasts and thrombocytosis . - pubmed
The strains tested had a negative impact on the survival of Eurytemora , as well as on the embryonic development and hatching regime of the Baltic herring . - pubmed
[ Review of Polish literature on human brucellosis from 1928 to 1958 ] . - pubmed
[ Development of a mouse mammary adenocarcinoma transplanted into a pneumoderma ] . - pubmed
The new continuous leukemia cell line MUTZ-11 was established in 1994 from the peripheral blood of a 60 - year - old woman with acute myeloid leukemia ( AML ) M4 ( following 2 years with myelodysplastic syndromes ) . - pubmed
The authors tested 11 patients with developmental prosopagnosia using this test , and a majority scored in the normal range . - pubmed
Government cleared in disabled man 's AIDS - related death . - pubmed
A hypercholesterolemic patient medicated with cerivastatin for 22 days resulted in acute rhabdomyolysis . - pubmed
OBJECTIVE : In the 7,12 - dimethylbenz [ a ] anthracene ( DMBA ) model of rat mammary carcinogenesis , microvascular density and angiogenic potential increase with progression from normal to invasive disease , but the mechanisms involved are unknown . - pubmed
Efficacy and safety of lanthanum carbonate for reduction of serum phosphorus in patients with chronic renal failure receiving hemodialysis . - pubmed
BACKGROUND : Lanthanum carbonate is a highly effective phosphate binder with significant potential as a treatment for hyperphosphatemia in patients with end - stage renal disease ( ESRD ) . - pubmed
CONCLUSION : Lanthanum carbonate is an effective and well - tolerated agent for the short - term treatment of hyperphosphatemia in patients with ESRD . - pubmed
Streptococcus pneumoniae is the most important bacterial cause of pneumonia and meningitis among adults world wide . - pubmed
It is a particularly common cause of these infections and also bacteraemia among HIV infected adults with rates of disease increasing to more than 100 times the normal as HIV infection progresses to AIDS . - pubmed
Factors underlying susceptibility to pneumococcal infection in HIV infected adults are then reviewed , along with the effectiveness of current vaccines . - pubmed
Finally , novel approaches that will be needed to combat PD in HIV afflicted parts of the world are suggested . - pubmed
To investigate the relationship between ischemia - reperfusion and apoptosis in the uterus , we analyzed a uterine ischemia - reperfusion model using BDF1 and C57BL/6 mice . - pubmed
Our mouse model could be suitable for investigating ischemia - related uterine injury in humans , particularly in menstruation . - pubmed
Neonatal HBV vaccination prevents adult cancer . - pubmed
In the prevention of acquired rubella , varicella , HBV , influenza , poliovirus , measles and hepatitis A , one should mention the added bonus of preventing secondary cases by preventing transmission from infants and children to other children and adults . - pubmed
Preventing paediatric HSV , HBV and HIV infection in females may even be preventing subsequent transmission to future generations . - pubmed
As a powerful predictor of future fracture risk , the identification of vertebral fracture helps target individuals who will benefit from anti - fracture therapy . - pubmed
[ Late course three - dimensional conformal radiotherapy in patients with stage III non - small cell lung cancer ] . - pubmed
OBJECTIVE : To evaluate the therapeutic efficacy and radiation complications of late course three - dimensional conformal radiotherapy ( 3DCRT ) in patients with stage III non - small cell lung cancer ( NSCLC ) . - pubmed
METHODS : Eighty - six patients with stage III NSCLC were randomly divided into group A ( n=42 ) receiving conventional radiotherapy at the total dose of 66 to 70 Gy in 33 to 35 fractions completed in 6 to 7 weeks and group B ( n=44 ) with late course 3DCRT at the dose of 24 - 30 Gy in 6 fractions ( 400 - 500 cGy per fraction every other day ) after 40 Gy conventional radiotherapy , completed in 5 to 6 weeks . - pubmed
CONCLUSION : Late course 3DCRT produces better therapeutic effects than conventional radiotherapy in patients with stage III NSCLC . - pubmed
We describe our experience in the case of a 71 - year - old woman with a posterior fossa DAVF who presented with sudden onset headache , collapse and neurological deficit secondary to a subarachnoid haemorrhage . - pubmed
Studies in the biochemistry of micro - organisms : Itaconic acid , a metabolic product of a strain of Aspergillus terreus Thom . - pubmed
METHODS : We investigated the influence of NO on the proliferation , cell cycle , apoptosis , and differentiation of immortalized human oral keratinocytes ( IHOK ) and primary oral cancer cells ( HN4 ) using the 3 -( 4,5 - dimethylthiazol-2 - yl )- 2,5 - diphenyltetrazolium bromide ( MTT ) assay , sulforhodamine B ( SRB ) assay , flow cytometry , nuclear DNA staining , and Western blotting . - pubmed
Extracts of Aesculus hippocastanum ( horse chestnut ) seed have been used in the treatment of chronic venous insufficiency , edema , and hemorrhoids . - pubmed
In addition , we analyzed the cell growth inhibitory effects and the induction of apoptosis in HT-29 human colon cancer cell line . - pubmed
To understand the growth inhibitory effects , HT-29 human colon carcinoma cell lines were treated with various concentrations of beta - escin and analyzed by flow cytometry for apoptosis and cell cycle progression . - pubmed
[ Effects of Siwu decoction on bone marrow protein expression of blood deficiency mice induced by cyclophosphamide ] . - pubmed
OBJECTIVE : To study the effects of Siwu decoction on protein expression of blood deficiency mice induced by cyclophosphamide ( CIX ) and discuss the possible molecular mechanism on blood enriching function of Siwu decoction . - pubmed
METHOD : Blood deficiency mice were established by injecting ip with 250 mg x kg(-1 ) CTX . - pubmed
RESULT : Siwu decoction could restore the changes of 12 up - regulated and 3 down - regulated proteins in bone marrow of blood deficiency mice induced by cyclosphosphamide . - pubmed
OBJECTIVES : To evaluate the changes in voiding symptoms in female patients with stress urinary incontinence ( SUI ) undergoing transvaginal sling techniques over a five - year period in the Department of Urology at the University Hospital of Albacete . - pubmed
METHODS : Between November 2001 and December 2005 126 patients with SUI ( mean age 57.09 years ; 36 - 78 ) underwent transvaginal sling techniques ( Sling in Fast , TVK TOT ) . - pubmed
The number of urinary leak episodes per day diminished in 114 patients ( 90.5 % ) with a mean decrease of 9.65 episodes ( 95 % CI : 8.56 - 10.79 ) ( p & lt ; 0.0001 ) . - pubmed
Hcy - thiolactone levels are elevated in hyperhomocysteinemic humans and mice . - pubmed
OBJECTIVE : To describe speech production longitudinally in a group of children with unilateral cleft lip and palate ( UCLP ) . - pubmed
PARTICIPANTS : Twenty consecutive children with UCLP and nine age - matched children without clefts in a comparison group . - pubmed
The most active compounds were N -[ 2 -( 4 - chlorophenoxymethyl )- benzoyl ]- N '-( 2,6 - dichlorophenyl )- thiourea ( 5 g ) and N -[ 2 -( 4 - chlorophenoxymethyl )- benzoyl ]- N '-( 4 - bromophenyl )- thiourea ( 5h ) , which showed a broad spectrum of antimicrobial activity against enterobacterial strains ( E. - pubmed
In this report , we present a case of a patient with severe mitral stenosis that underwent successful video - assisted minimally invasive mitral valve replacement . - pubmed
Alpha - ZrPN were applied for the analysis of tryptic digests of mouse liver and leukemia cell phosphoproteomes and succeeded in identifying 158 phosphopeptides ( 209 phosphorylation sites ) from 101 phosphoproteins in mouse liver lysate and 78 phosphopeptides ( 104 phosphorylation sites ) from 59 phosphoproteins in leukemia cell extract . - pubmed
This review will highlight the developments in cellular medicine that may soon permit interventional pain management physicians to treat a much wider variety of clinical conditions and highlight an interventional case study using these technologies OBJECTIVE : To determine if isolated and expanded human autologous mesenchymal stem cells could effectively regenerate cartilage and meniscal tissue when percutaneously injected into knees . - pubmed
CONCLUSION : The described process of autologous mesenchymal stem cell culture and percutaneous injection into a knee with symptomatic and radiographic degenerative joint disease resulted in significant cartilage growth , decreased pain and increased joint mobility in this patient . - pubmed
We compared the surgical outcomes of recent patients with cerebellopontine angle ( CPA ) epidermoids treated with advanced surgical tools with those of patients treated in earlier series . - pubmed
From November 2000 to June 2004 , we treated 12 patients with epidermoid tumors . - pubmed
Total removal was achieved in 7 of the 10 patients with unilateral CPA epidermoids . - pubmed
Clinical criteria are persistent erythematous macules and annular lesions with a red - brown edge and a central hypopigmentation usually found on the flanks and groins of children and adolescents . - pubmed
RESULTS : Significant left main stem disease was present in 54 patients ( 6.8 % ) . - pubmed
71 patients ( 9 % ) had at least one of the events comprised in the combined study end - point ( unstable angina , myocardial infarction ( AMI ) and cardiac death ) . - pubmed
RESULTS : The rate of major adverse cardiac events including death , myocardial infarction , and target vessel revascularization in patients excluded from randomization ( n = 343 ) was significantly higher at 30 days ( 10.2 % vs. 1.6 % ) , 6 months ( 17.5 % vs. 5.6 % ) , and 12 months ( 24.5 % vs. 9 % ) compared with randomized patients ( n = 1,005 ; P & lt ; 0.0001 ) . - pubmed
[ Pleuropulmonary blastoma in an adult women with pleurorrhea as the major clinical manifestation : report of a case ] . - pubmed
OBJECTIVE : Pleuropulmonary blastoma ( PPB ) is a rare dysontogenetic neoplasm in children and has been recognized as a distinct clinicopathological entity different from the ordinary pulmonary blastoma of adulthood . - pubmed
A new yeast species , Vanderwaltozyma verrucispora , is proposed in this study based on two strains isolated from partially decayed leaves in Japan and one strain from soil in Taiwan . - pubmed
CONCLUSION : The results of this meta - analysis suggest an improvement of survival in the patients treated with the targeted therapies approved for pulmonary arterial hypertension . - pubmed
Depending on the patient 's cooperation and the fracture stability , a lower - leg cast may additionally be applied . - pubmed
Fifty - six pregnant women with gestational diabetes mellitus ( GDM ) and 42 normal glucose tolerant ( NGT ) pregnant women between 26 and 36 gestational weeks were included in the study prospectively . - pubmed
BACKGROUND & amp ; AIMS : Epstein - Barr virus ( EBV ) has been causally associated with cancer ; some gastric carcinomas have a monoclonal EBV genome in every cancer cell , indicating that they arose from a single infected progenitor cell . - pubmed
METHODS : We conducted a meta - analysis of 70 studies including 15,952 cases of gastric cancer assessed by in situ hybridization for EBV - encoded small RNA . - pubmed
RESULTS : The pooled prevalence estimate of EBV positivity was 8.7 % ( 95 % confidence interval [ CI ] : 7.5%-10.0 % ) overall , with a 2 - fold difference by sex : 11.1 % ( 95 % CI : 8.7%-14.1 % ) of gastric cancer cases in males vs 5.2 % ( 95 % CI : 3.6%-7.4 % ) of cases in females . - pubmed
EBV prevalence was 4 times higher ( 35.1 % ) for tumors in postsurgical gastric stump / remnants . - pubmed
Over 90 % of lymphoepithelioma - like carcinomas were EBV positive , but only 15 studies reported any cases of this type ; prevalence did not significantly differ between the more common diffuse ( 9.5 % ) [ corrected ] and intestinal ( 7.6 % ) [ corrected ] histologies . - pubmed
Epidemiologic studies comparing EBV - positive and -negative gastric cancers are warranted to investigate EBV 's role in gastric carcinogenesis . - pubmed
Osteoporosis in women with breast cancer and its effect on quality of life : a pilot study . - pubmed
PURPOSE : The primary aim of this study was to evaluate the risk of osteoporosis ( OP ) in patients who had received adjuvant chemotherapy for breast cancer . - pubmed
PATIENTS AND METHODS : Twenty - six patients with breast cancer and 21 healthy controls were recruited into the study . - pubmed
All breast cancer patients were treated with 6 cycles of adjuvant chemotherapy . - pubmed
The most affected domain of the SF-36 in patients with breast cancer was the physical role . - pubmed
OP should be investigated during follow - up in order to improve the quality of life of the surviving breast cancer patients . - pubmed
RESULTS : The study population consisted of 40 rheumatoid arthritis ( RA ) , 34 ankylosing spondylitis ( AS ) , 9 juvenile rheumatoid arthritis ( JRA ) , and 3 other patients . - pubmed
Investigations of naturally occurring mutations , such as the deletional thalassaemias and hereditary persistence of fetal haemoglobins ( HPFHs ) , have brought many insights into human globin switching , but limited data have been reported so far . - pubmed
CONCLUSIONS : Time to first detectable uPSA identifies men with low - risk recurrence prostate cancer . - pubmed
METHODS : We prospectively evaluated the diagnostic efficacy of the cell block ( CB ) method and that of smear cytology using tissue samples obtained in the same needle pass at EUS - FNA in 33 patients with pancreatic tumors , abdominal tumors or swollen lymph nodes . - pubmed
DJD - associated pain in cats : what can we do to promote patient comfort ? - pubmed
PRACTICAL RELEVANCE : Degenerative joint disease ( DJD ) has a high prevalence in domestic cats and can be associated with pain . - pubmed
AUDIENCE : All practitioners are faced with cats that are mobility impaired due to DJD - associated pain . - pubmed
PATIENT GROUP : Cats of all ages and breeds , and either sex , can experience DJD - associated discomfort . - pubmed
CLINICAL CHALLENGES : Recognizing DJD and assessing DJD - associated pain in cats is a challenge . - pubmed
Current understanding of the etiology of feline DJD and the mechanisms of DJD - associated pain is incomplete , making the rational choice of treatments a further challenge . - pubmed
EVIDENCE BASE : Evidence is emerging on the prevalence of feline DJD , and on how to assess the associated pain and mobility impairment . - pubmed
There is a lack of information on the etiology of feline DJD and a relative lack of data on the efficacy of putative treatments . - pubmed
Of 116 patients , 69 % had optimal follow - up of MGUS . - pubmed
High - risk MGUS patients ( & gt;= 1.5 g / dL and/or non - IgG MGUS ) were more likely to be optimally followed ( 81 % vs 64 % ) , and be diagnosed with MM secondary to serial follow - up testing ( 21 % vs 7 % ) . - pubmed
Future studies are needed to replicate and expand our findings and to determine the optimal frequency of monitoring in higher - risk MGUS patients . - pubmed
In many patients , no treatment is ever necessary -- because IHs are well known for their natural history of spontaneous involution . - pubmed
Primary spinal cord oligodendroglial tumor is very rare , and in only one patient with spinal cord oligodendroglioma has a deletion of chromosome 1p/19q been reported . - pubmed
We present the case of an 18 - year - old girl , who had one - year lower back pain and one - month lower limb weakness . - pubmed
After treatment with temozolomide for six months , the patient had a remarkable improvement of her lower limb symptoms , and complete imaging regression of the residual tumor showed no evidence of recurrence at any other sites . - pubmed
It is also the first case of the patient with recurrent intramedullary anaplastic oligodendroglioma who had a significant clinical improvement and complete imaging remission after subtotal resection then treatment with temozolomide chemotherapy . - pubmed
To describe uncommon association between central retinal artery obstruction and dominant macular drusen in two young female patients . - pubmed
Second patient , a 34 - year - old female with a previous history of right central retinal artery obstruction diagnosed elsewhere . - pubmed
Antenatal nicotine induces heightened oxidative stress and vascular dysfunction in rat offspring . - pubmed
Outcome and predictors of treatment failure in total hip / knee prosthetic joint infections due to Staphylococcus aureus . - pubmed
BACKGROUND : Variables associated with the outcome of patients treated for prosthetic joint infections ( PJIs ) due to Staphylococcus aureus are not well known . - pubmed
METHODS : The medical records of patients treated surgically for total hip or knee prosthesis infection due to S. - pubmed
aureus ( MRSA)-related PJIs were not associated with worse outcome , compared with methicillin - susceptible S. - pubmed
CONCLUSIONS : The results of the present study suggest that the ASA score significantly affects the outcome of patients treated for total hip and knee prosthetic infections due to MSSA or MRSA and that rifampin combination therapy is associated with a better outcome for these patients when compared with other antibiotic regimens . - pubmed
RESULTS : Pancreatic beta cells from Zucker fa / fa rats and obese individuals were found to be hyper - responsive to glucose . - pubmed
In 2 elderly patients ( 1 % ) , a minor dural injury with a cerebrospinal fluid leak was controlled during the operation with temporalis fascia grafting . - pubmed
In 1 patient ( 0.5 % ) , a subdural hematoma was observed after bipolar cauterization of a prominent diploic vein . - pubmed
We found that all three strains of T. - pubmed
METHODS : The clinical and outcome data of all advanced ovarian , primary peritoneal and tubal carcinoma patients who after diagnosis had neoadjuvant chemotherapy and underwent interval debulking during the period 2000 - 2010 , were abstracted . - pubmed
OBJECTIVE : This study was carried out between June - December 2008 to determine the prevalence of toxoplasmosis in Pirlak sheep in the Suhut district of Afyonkarahisar . - pubmed
Greater physician awareness about these potential infections is important to optimize patient outcomes through early recognition and potential preventive strategies . - pubmed
Mild - to - moderate alveolitis was observed in the histopathological test of lungs from GSEI and EPEV virus - infected mice . - pubmed
Tooth agenesis is one of the most common developmental disorders in humans . - pubmed
We conducted a single - center retrospective study in patients with lymphoma and myeloma treated at Brest Hospital to assess the cost reductions related to and the efficiency and safety of filgrastim biosimilars . - pubmed
We identified 65 patients with lymphoma or myeloma treated with filgrastim biosimilars for ASCT and compared 19 parameters of these patients , including BM recovery , side effects , infectious complications and treatment costs , with published historical data on a cohort of 50 patients treated with classic filgrastim . - pubmed
PATIENTS : Children with clinical deterioration , defined as cardiopulmonary arrest , acute respiratory compromise , or urgent intensive care unit transfer while hospitalized on pediatric wards ( n = 141 ) . - pubmed
Physical predictors for moderate to severe obstructive sleep apnea in snoring patients . - pubmed
PURPOSE : This study aimed to identify physical findings that may predict the presence of moderate to severe obstructive sleep apnea ( OSA ) in snoring patients . - pubmed
METHODS : A total of 283 subjects ( 165 males and 118 females ) were recruited , including 217 OSA patients and 66 patients with apnea - hypopnea index ( AHI)<5 as a control group , diagnosed by level-1 polysomnography . - pubmed
Arsenic trioxide ( ATO ) is being successfully used as a first and second line therapy for the treatment of patients with acute promyelocytic leukemia . - pubmed
Results indicated that pre - training or pre - test intra - CA1 administration of scopolamine ( 1.5 and 3 mug / rat ) dose - dependently reduced the step - through latency , showing an amnestic response . - pubmed
The pre - training scopolamine - induced amnesia ( 3 mug / rat ) was reversed by the pre - test administration of scopolamine , indicating a state - dependent effect . - pubmed
Pneumothorax occurred in 3.1 % of patients , requiring chest tube drainage in 1.6 % of these cases . - pubmed
Among them is the tumor differentially expressed ( TDE ) protein family , which shows no homologue to any other protein families and is unique to eukaryotes . - pubmed
Goserelin fosters bone elongation but does not prevent ovarian damage in cyclophosphamide - treated prepubertal mice . - pubmed
ANIMAL(S ): C57BL/6J mouse strain . - pubmed
, 8708 DALYs / year for hepatitis B virus and 740 DALYs / year for measles virus . - pubmed
METHODS : In all , 87 unselected consecutive hospitalizations due to AECOPD in 61 subjects and a total of 190 consecutive subjects with stable COPD were recruited . - pubmed
Only 5.6 % of AECOPD subjects were associated with systolic dysfunction defined as a left ventricular ejection fraction ( LVEF ) & lt;50 % ; a further 7.4 % were considered to have impaired relaxation defined as an E / A wave velocity ratio & lt;0.8 and a deceleration time of E & gt;240 ms . - pubmed
Mycoplasma genitalium is an emerging sexually transmitted pathogen associated with reproductive tract disease in men and women , and it can persist for months to years despite the development of a robust antibody response . - pubmed
The histocompatibility efficacy of these nerve guide scaffolds was tested in a rat model for peripheral nerve injury treatment . - pubmed
Based on the compelling evidence of the randomized Placement of Aortic transcatheter valves ( PARTNER ) A and B cohort , TAVI is now considered standard of care for extreme risk and inoperable patients and is an alternative to surgery for high - risk patients with symptomatic aortic stenosis . - pubmed
This case shows that Hermansky - Pudlak syndrome should be considered in the differential diagnosis of a patient presenting with bleeding diathesis , when the clinical presentation also includes oculocutaneous albinism and visual problems . - pubmed
We shortly introduce these channels , summarize nomenclature and chromosomal location of the 28 mammalian Trp genes , and list the available Trp - deficient mouse lines . - pubmed
Different effects of bifeprunox , aripiprazole , and haloperidol on body weight gain , food and water intake , and locomotor activity in rats . - pubmed
In this study , the changes in elemental composition that occurred in the hippocampal formation in the electrical kindling model of seizures were examined to determine the mechanisms responsible for the phenomenon of kindling and spontaneous seizure activity that may occur in this animal model . - pubmed
MATERIALS & amp ; METHODS : Ex vivo biochemical experiments with human platelets and exosomes , and FeCl3 -induced murine carotid artery thrombosis . - pubmed
Injected exosomes inhibited occlusive thrombosis in FeCl3 -damaged murine carotid arteries . - pubmed
Control platelets infused into irradiated , thrombocytopenic mice reconstituted thrombosis in damaged carotid arteries , but failed to do so after prior ex vivo incubation with exosomes . - pubmed
INTRODUCTION : We evaluated the characteristics of thyroid carcinoma in geriatric patients and outcomes after a 10 - years follow - up . - pubmed
METHODS : Comparative retrospective study on a group of 31 geriatric patients and one of 224 non - geriatric , who underwent surgery for thyroid carcinoma in the period 1998 - 2003 . - pubmed
We compared with Fisher 's exact test : histology , multifocality , tumor size , lymph - node metastasis , distant metastasis , persistence / recurrence and mortality , including and excluding anaplastic carcinomas , in a subgroup of 26 geriatric patients and another of 223 non - geriatric patients . - pubmed
DISCUSSION : Thyroid carcinoma is more aggressive in geriatric patients . - pubmed
CONCLUSION : It would be useful to undertake randomized prospective studies on a large cohort of patients to determine the most effective therapy for geriatric patients suffering from thyroid carcinoma . - pubmed
These studies enrolled mostly treatment - resistant depression patients , who received daily stimulation sessions on the left dorsolateral prefrontal cortex . - pubmed
Abortion and foetal lesions induced by Neospora caninum in experimentally infected water buffalos ( Bubalus bubalis ) . - pubmed
It has been postulated that buffalo may be resistant to abortion caused by neosporosis , because of high serological prevalences found in buffalo herds from different localities , with no description of Neospora caninum - related abortion . - pubmed
Recent studies have demonstrated the potential impact of neosporosis in pregnant water buffalo cows . - pubmed
In this work , three pregnant buffalo cows were experimentally infected with Nc-1 strain of N. - pubmed
Here , we report a case of this uncommon sub type of ameloblastoma in a young female patient presenting as an extensive lesion in mandibular ramus area . - pubmed
Patient underwent segmental mandibulectomy and histological examination of excisional specimen revealed features of ameloblastoma with abundant keratinization leading to a diagnosis of keratoameloblastoma . - pubmed
We reviewed outcomes for 84 patients treated with clofarabine for relapsed or refractory AML or MDS , either with clofarabine as monotherapy ( n=19 ) or in combination with cytarabine ( n=65 ) . - pubmed
We describe clinical and muscle biopsy findings of a patient with sarcoidosis and inclusion body myositis . - pubmed
A 66 - year - old man presented with a 6 - year history of progressive , asymmetrical and selective weakness of the quadriceps , biceps and finger flexor muscles ; he had a remote history of pulmonary sarcoidosis . - pubmed
INTERVENTIONS : Patients were organized by date of dysplasia diagnosis , divided into 2 groups ( group 1 , January 1 , 1993 , through December 31 , 2002 ; group 2 , January 1 , 2003 , through December 31 , 2012 ) , and compared against one another . - pubmed
Fish oil , which contains omega-3 fatty acids mainly in the form of triglycerides , has benefits for reducing breast cancer risk , similar to tamoxifen action . - pubmed
METHODS : Clinical data of 316 surgical GBC patients were analyzed retrospectively , and preoperative serum platelet and lymphocyte counts were used to calculate the PLR . - pubmed
Then , we conducted multivariate Cox analysis to assess the independent effect of the PLR on the survival of GBC patients . - pubmed
CONCLUSION : The PLR could be used as a simple , inexpensive , and valuable tool for predicting the prognosis of GBC patients . - pubmed
David 's procedure is also feasible in patients with bicuspid aortic valve ( BA ) , though few long - term data are available . - pubmed
METHODS : An analysis was conducted of the long - term echocardiographic data from patients with BAV who had undergone David 's procedure at early and long - term follow up ( FU ) examinations . - pubmed
RESULTS : Between 1994 and 2010 , a total of 30 patients with BAV underwent David 's procedure at the authors'institution . - pubmed
Four patients ( 13 % ) had to be reoperated after 10.00 + - 4.74 years ( range : 5.49 - 17.06 years ) due to aortic stenosis ( n = 1 ) and aortic insufficiency ( n = 3 ) ; the latter three patients had a significant prolapse of both the fused and the non - coronary cusp of reconstruction . - pubmed
Patients with prolapsing non - coronary leaflet at reconstruction seemed vulnerable to recurrent AR . - pubmed
METHODS AND RESULTS : Four groups of patients undergoing TAVI in the Placement of Aortic Transcatheter Valves ( PARTNER ) trial and registries were compared : prior PPM ( n=586 ) , new PPM ( n=173 ) , no PPM ( n=1612 ) , and left bundle branch block ( LBBB)/no PPM ( n=160 ) . - pubmed
CONCLUSIONS : In the PARTNER trial , prior PPM , along with new PPM and chronic LBBB patients , had worsened clinical and echocardiographic outcomes relative to no PPM patients , and the presence of a PPM was independently associated with 1 - year mortality . - pubmed
chagasi was expressed in three different strains of Escherichia coli . - pubmed
chagasi may be a useful tool in the diagnosis of CVL , and further tests regarding the infection stage and the specie of parasite at which the dogs are sampled should provide a better understanding of our results . - pubmed
The treatment goal for CBS - deficient patients is to normalize the metabolic values of these three metabolites using a combination of vitamin therapy and dietary manipulation . - pubmed
To better understand the effectiveness of nutritional treatment strategies , we have performed a series of long - term dietary manipulation studies using our previously developed Tg - I278 T Cbs(-/- ) mouse model of CBS deficiency and sibling Tg - I278 T Cbs(+/- ) controls . - pubmed
BACKGROUND : Femoroacetabular impingement ( FAI ) has been reported as a cause of hip pain in young patients and is suggested as the trigger for hip osteoarthritis ( OA ) . - pubmed
The goal of this study was to quantify the metabolic profiles of articular tissues ( cartilage , synovium , and labrum ) harvested from patients with FAI and with end - stage OA . - pubmed
The differences in gene expression in articular tissues from the patients with FAI were also evaluated on the basis of clinical parameters ( age range and alpha angle ) . - pubmed
CONCLUSIONS : Our results indicate that the metabolic conditions of articular cartilage in FAI and OA are different and that the expression of genes associated with inflammation is greater in the articular cartilage of patients with FAI compared with the synovium and the labrum . - pubmed
CLINICAL RELEVANCE : The articular cartilage from the impingement lesion in patients with FAI showed biologically higher inflammation and degeneration , supporting the concept that FAI may be a trigger for joint degeneration . - pubmed
METHODS : A total of 172 multiply injured patients ( mean Injury Severity Score [ ISS ] 26.7 ) recruited from eight trauma centres participating in the German Trauma Registry were compared with 166 marginally injured patients ( mean ISS 3.9 ) . - pubmed
Deep brain stimulation at low frequency improves dysphagia and freezing of gait in Parkinson patients . - pubmed
Bimagrumab seems to increase muscular volume and force in patients with inclusion body myositis . - pubmed
Place of Colistin - Rifampicin Association in the Treatment of Multidrug - Resistant Acinetobacter Baumannii Meningitis : A Case Study . - pubmed
Treatment of Acinetobacter baumannii meningitis is an important challenge due to the accumulation of resistance of this bacteria and low meningeal diffusion of several antimicrobial requiring use of an antimicrobial effective combination to eradicate these species . - pubmed
We report a case of Acinetobacter baumannii multidrug - resistant nosocomial meningitis which was successfully treated with intravenous and intrathecal colistin associated with rifampicin . - pubmed
Proton Therapy in Children : A Systematic Review of Clinical Effectiveness in 15 Pediatric Cancers . - pubmed
For chondrosarcoma , chordoma , craniopharyngioma , ependymoma , esthesioneuroblastoma , Ewing sarcoma , central nervous system germinoma , glioma , medulloblastoma , osteosarcoma , and rhabdomyosarcoma , there was insufficient evidence to either support or refute PT in children . - pubmed
For patients with RRMS , what are the pharmacological strategies for patients not adequately controlled on initial pharmacotherapy ? - pubmed
Should combination strategies be considered for treatment of patients with RRMS ? - pubmed
We aimed to assess the outcomes after a single catheter ablation procedure , comparing PVI using CRYO vs. RF ablation for PVI plus additional ablation in a cohort of patients with persistent AF . - pubmed
METHODS : In this prospective multicenter propensity score - matched comparison , 59 consecutive patients undergoing CRYO ablation of persistent AF were matched to 59 patients treated with RF from November 2010 to June 2012 . - pubmed
RESULTS : During a mean follow - up of 15.6 + - 11.5 months , 43.2 % of patients presented atrial arrhythmia relapse after a blanking period of 3 months , which was comparable between the two groups ( 40.7 % in CRYO vs. 45.8 % in RF , Log rank P = 0.14 ; HR = 0.67 , 95 % CI 0.38 - 1.16 , P = 0.15 ) , despite the fact that 52.5 % of RF patients add additional complex fractionated atrial electrogram ablation , as well as left atrial linear ablation in over two - thirds ( roof line in 67.8 % and mitral isthmus in 32.2 % ) . - pubmed
CONCLUSION : In our multicenter experience , freedom from atrial arrhythmias was comparable among matched patients treated with CRYO and RF , despite non - significant trends in favor of RF in terms of complications , at the cost of longer procedure times . - pubmed
Here we compare genital shedding patterns of herpes simplex virus-2 ( HSV-2 ) in 98 HIV infected and 98 HIV uninfected men matched on length of infection , HSV-1 serostatus and nationality . - pubmed
Iron Deficiency Induces a Partial Inhibition of the Photosynthetic Electron Transport and a High Sensitivity to Light in the Diatom Phaeodactylum tricornutum . - pubmed
In this study , a combination of thermoluminescence ( TL ) , chlorophyll fluorescence , and P700 absorbance measurements have been used to elucidate the effects of iron deficiency in the photosynthetic electron transport of the marine diatom P. - pubmed
Iron deficiency also induced a marked increase in light sensitivity in P. - pubmed
A reduction in left ventricular ( LV ) global longitudinal strain in all patients , or reduction in LV global circumferential strain or global radial strain in patients at intermediate to high risk for cardiotoxicity , despite normal LV ejection fraction warrants a clinical assessment on the benefits of continuing cardiotoxic chemotherapeutic agents . - pubmed
Listeria monocytogenes sequence type 204 ( ST204 ) strains have been isolated from a range of food , environmental , and clinical sources in Australia . - pubmed
All patients alive 90 days after pancreatoduodenectomy for M0 -pancreatic cancer between 2008 and 2013 in the Netherlands were included in this study . - pubmed
Of the 1195 patients undergoing a pancreatoduodenectomy for pancreatic cancer , 642 ( 54 % ) patients received adjuvant chemotherapy . - pubmed
Patients with a higher tumor stage , younger age , and diagnosed more recently were more likely to receive adjuvant treatment . - pubmed
The finding that elderly patients and patients with a low tumor stage are less likely to undergo treatment needs further attention , especially since adjuvant treatment is known to prolong survival in most of these patients . - pubmed
OBJECTIVE : To evaluate potential development of tolerance to adjunctive clobazam in patients with Lennox - Gastaut syndrome . - pubmed
Individual patient listings were reviewed for dosage increases & gt;=40 % and increasing seizure rates . - pubmed
For patients free of drop seizures , there was no notable change in dosage over 24 months . - pubmed
Few patients had a dosage increase & gt;=40 % associated with an increase in seizure rates . - pubmed
A total of 16 patients ( 20.8 % ) had severe postoperative thrombocytopenia ( & lt;50x103 / mm3 ) . - pubmed
The incidence of severe thrombocytopenia was significantly higher ( p = 0.046 ) in Perceval S patients ( n = 9 ; 33.3 % ) than in Mitroflow patients ( n = 7 ; 14 % ) . - pubmed
The platelet count recovered in all patients with severe thrombocytopenia . - pubmed
To further understand the role of lipogenesis and lipotoxicity in the development of obesity and diabetes , lipidomes of various organs from ob / ob mice and their wild type controls were analyzed by shotgun lipidomics at 10 , 12 , and 16 weeks of age . - pubmed
Moreover , levels of lipotoxic lipid classes were significantly higher in ob / ob mice than their age - matched controls , supporting the notion that elevated lipotoxic components are tightly associated with insulin resistance in ob / ob mice . - pubmed
Taken together , the current study revealed that lipogenesis and lipotoxicity in ob / ob mice likely contribute to insulin resistance and provides great insights into the underlying mechanisms of diabetes and obesity . - pubmed
METHODS : We prospectively studied 708 type-2 diabetes patients [ 433 men ( [ 61.2 % ) ] , candidate for isolated coronary artery bypass grafting . - pubmed
All patients were telemonitored for 72 hours after operation for the occurrence of atrial fibrillation . - pubmed
RESULTS : A total of 109 ( 15.3 % ) patients developed POAF . - pubmed
Patients in the atrial fibrillation group tended to be older , with prolonged longer diabetes , and have renal failure , chronic obstructive pulmonary disease , and hypertension . - pubmed
Medical Management of Extensive Arterial Thromboembolism in a Patient with Essential Thrombocythemia and Warfarin Failure . - pubmed
Patients with ET and PV are at an increased risk for thromboembolic and hemorrhagic events . - pubmed
We assessed the preliminary efficacy , tolerability , and safety of azithromycin compared with placebo in the treatment of OCD and associated symptoms in children with pediatric acute - onset neuropsychiatric syndrome ( PANS ) . - pubmed
The primary outcome , obsessive - compulsive symptom severity , was assessed using the OCD Clinical Global Impressions Severity ( CGI - S OCD ) and Children 's Yale - Brown Obsessive Compulsive Scale ( CY - BOCS ) . - pubmed
RESULTS : Participants in the azithromycin group ( n = 17 ) showed significantly greater reductions in OCD severity on the CGI - S OCD than the placebo group ( n = 14 ) posttreatment ( p = 0.003 ) , although there were no significant differences on the CY - BOCS . - pubmed
OBJECTIVES : Statins may improve outcomes in patients with chronic liver disease ( CLD ) . - pubmed
METHODS AND MATERIALS : A retrospective analysis of patients receiving palliative RT for axial skeletal bone metastases from 2012 to 2014 was conducted . - pubmed
Patient and treatment characteristics were obtained including dosimetric variables , acute toxicity , and subjective pain during treatment and in the acute posttreatment period ( & lt;=60 days after completion ) . - pubmed
The patient was an emergency transported , 57 - year - old man complaining of left thoraco - lateroabdominal pain , with a history of blunt chest trauma 3 months prior . - pubmed
Laparoscopic - assisted percutaneous nephrolithotomy as an alternative in the treatment of complex renal calculi in patients with retrorenal colon . - pubmed
There were 969 case patients who experienced a primary cardiovascular outcome , and there were 3170 control patients who were event free at the time of a case event and had the same type of index ACS ( unstable angina or myocardial infarction ) as that of the respective case patients . - pubmed
OBJECTIVE : To evaluate outcomes for RBU in a multi - institutional cohort of patients treated for revision ureteropelvic junction obstruction and long or multifocal ureteral stricture at three tertiary referral centers . - pubmed
This study aims to evaluate the impact of covert hepatic encephalopathy on the emotional state and which factors are associated with changes in the emotional state in patients with cirrhosis . - pubmed
METHODS : This single - center study included all patients with cirrhosis who underwent the portosystemic encephalopathy syndrome ( PSE ) test , critical flicker frequency , and emotional state assessment with the Eigenschaftsworterliste 60 - S in 2011 . - pubmed
RESULTS : One hundred seventeen patients with cirrhosis were included ( median age : 59 [ interquartile range : 48 - 67 ] , 32 % female , 74 % alcohol - associated ) . - pubmed
Seventy patients had covert hepatic encephalopathy ( 60 % ) with a higher MELD ( 16 [ interquartile range : 13 - 21 ] , p = 0.001 ) and a higher Child - Pugh score ( p = 0.003 ) compared to patients without encephalopathy . - pubmed
Patients with covert encephalopathy felt reduced mental activity ( p = 0.004 ) , lower general well - being ( p = 0.001 ) , and reduced extraversion ( p = 0.021 ) . - pubmed
The scores in the negative domains such as general lethargy ( p = 0.031 ) and anxiousness / depressiveness ( p = 0.033 ) were higher in patients with covert hepatic encephalopathy . - pubmed
Patients with 2 pathological tests ( critical flicker frequency and PSE ) showed the most distinct alterations in the emotional state in the group of patients with covert hepatic encephalopathy . - pubmed
CONCLUSIONS : Patients with covert hepatic encephalopathy have an alteration of the emotional state , which is more marked in patients with 2 pathological tests . - pubmed
Across a range of countries , the model results indicate that a more efficient allocation of HIV resources could reduce cumulative new HIV infections by an average of 18 % over the years to 2020 and 25 % over the years to 2030 , along with an approximately 25 % reduction in deaths for both timelines . - pubmed
METHODS : Seventy - nine patients diagnosed with OCD who received a standardized combination of treatments for 10 continuous years were divided into three groups according to their improvement rates on the Yale - Brown Obsessive - Compulsive Scale after 10 years of treatment . - pubmed
Prevalence and distribution of HPV genotypes and cervical - associated lesions in sexually active young French women following HPV vaccine . - pubmed
OBJECTIVE : To estimate the overall prevalence and distribution of HPV in vaccinated , sexually active young French women who were screened for cervical cancer by cytology and HPV testing . - pubmed
METHODS : High - risk HPV ( HR - HPV ) prevalence , genotype - specific prevalence and extent of multiple infections were assessed in 125 cervical samples from females with available vaccine data using hc2 assay and INNO - LiPA assay . - pubmed
CONCLUSION : Among HPV - vaccinated young women , HR - HPV are detected at a high rate , and an association with the grade of cytological abnormalities was observed . - pubmed
Congenital Microphthalmic Syndrome in a Swine . - pubmed
A 17 - week - old crossbred finishing pig was presented for lameness of approximately one week . - pubmed
To the authors ' knowledge , this is the first case report describing in detail histopathological changes in the porcine congenital microphthalmic syndrome . - pubmed
The role of extended infusion beta - lactams in the treatment of bloodstream infections in patients with liver cirrhosis . - pubmed
INTRODUCTION : Bloodstream infections ( BSIs ) in patients with liver cirrhosis are associated with significant morbidity and mortality . - pubmed
Areas covered : This review covers several aspects of how the pharmacokinetic / pharmacodynamic behavior of antimicrobials may change in patients with liver cirrhosis . - pubmed
Common features of cirrhosis , including hypoproteinemia , third space expansion and impairment of renal function may alter drug distribution in patients receiving hydrophilic drugs like beta - lactams , which are often frontline agents . - pubmed
Expert commentary : Observational studies have suggested that cirrhotic patients have improved outcomes when beta - lactam therapy is administered by extended or continuum infusion . - pubmed
Further studies are being completed to determine the optimal timing , depth and duration of hypothermia to optimize patient outcomes . - pubmed
METHODS : This was a cross - sectional study of 403 participants with asthma , aged 17 - 75 years , from three Swedish centres . - pubmed
CASE DESCRIPTION : The patient presented with heart failure immediately after birth . - pubmed
Patient 's characteristics at baseline , including New York Heart Association class , ejection fraction , QRS width and morphology , ischaemic aetiology of cardiomyopathy ( ICM ) , number of scarred segments , age at implantation , atrial fibrillation , and mechanical dyssynchrony ( Dyss ) were analysed . - pubmed
Women ( 24 % of the population ) had less ICM ( 23 % vs. 49 % , P & lt ; 0.0001 ) , less scarred segments ( 0.4 + - 1.3 vs. 1.0 + - 2.1 , P & lt ; 0.0001 ) , more left bundle branch block ( LBBB ; 87 % vs. 80 % , P = 0.01 ) , and more Dyss at baseline ( 78 % vs. 57 % , P & lt ; 0.0001 ) . - pubmed
Its antibacterial activity over six oral bacteria was analyzed using the microdilution method , and its cytotoxicity in osteoblasts was assessed with the MTT assay . - pubmed
Of the five Plasmodium species that are pathogenic to humans , infection with Plasmodium falciparum leads to fulminant progression of the disease with massive impact on pregnancy . - pubmed
Clinical efficacy of acute respiratory viral infections prevention in patients with chronic heart failure . - pubmed
MATERIALS AND METHODS : Conducted a comprehensive survey , dynamic monitoring and treatment of 60 patients aged from 49 to 70 years ( mean age 60.25 + -4.57 years , 17 men and 43 women ) with CHF with preserved ejection fraction of left ventricle ( LVEF ) ( & gt;=50 % ) , II - III functional class ( FC ) according to the classification of new York Heart Association ( NYHA ) , which developed as a result of coronary heart disease ( CHD ) , hypertensive disease ( HD ) . - pubmed
Of these , 30 patients ( group 1 ) on the background of standard therapy for CHF received for the prevention of ARVI tiloron ( Amixin ) at a dose of 125 mg once a week for 6 weeks , two courses for 1 year . - pubmed
Group 2 patients received only standard therapy for CHF . - pubmed
The positive dynamics of biomarkers of systemic inflammation and neurohormonal activation explains the improvement of the clinical course in patients with CHF ( increase of tolerance to physical loads , reducing the number of visits to General practitioner and hospital admissions in the hospital during 12 months of observation ) . - pubmed
CONCLUSION : A promising approach to the prevention of SARS in patients with CHF is course therapy with Amixin ( 2 times a year before the seasonal rising in the incidence of respiratory viral infections and influenza ) , which allows to achieve both decreasing in the frequency of SARS per year , and improvement the clinical course of CHF . - pubmed
A total of 60 participants with SAP ( n=20 ) , AMI ( n=20 ) and non - CHD controls ( n=20 ) were enrolled . - pubmed
Moreover , there was a more marked increase in the expression of these indicators in AMI patients when compared to SAP patients . - pubmed
Association between physician - staffed ambulances and patient prognoses after out - of - hospital cardiac arrests with respect to shockable and non - shockable rhythms : a retrospective observational study in a southern area of Shiga Prefecture Japan . - pubmed
Our observations could provide more appropriate prehospital treatment options for OHCA patients . - pubmed
parahaemolyticus to twenty - six bacterial and yeast strains and use the beneficial ones to enrich live food ( Branchiopod , Artemia franciscana , rotifer , Brachionus plicatilis and copepod , Tigriopus japonicus ) . - pubmed
From the total bacteria and yeast strains that were used , Candida parapsilosis , Pseudoalteromonas flavipulchra , Lactobacillus sakei , Bacillus natto , and B. - pubmed
Obstructive voiding symptoms in female patients with overactive bladder syndrome . - pubmed
The proportions of patients who suffered relapse after 6 months , 1 year , and 2 years were 28 % , 31 % , and 40 % for the postpartum group and 39 % , 50 % , and 55 % for the nonpostpartum group . - pubmed
Contrast sensitivity and visual acuity in subjects wearing multifocal contact lenses with high additions designed for myopia progression control . - pubmed
Correction to : Oral inoculation of ultraviolet - irradiated Eimeria species oocysts protects chickens against coccidiosis . - pubmed
The Short - Term Cost - Effectiveness of Once - Weekly Semaglutide Versus Once - Daily Sitagliptin and Once - Weekly Dulaglutide for the Treatment of Patients with Type 2 Diabetes : A Cost of Control Analysis in Spain . - pubmed
These trials also assessed the proportions of patients achieving treatment targets capturing glycemic control and avoidance of hypoglycemia and weight gain . - pubmed
This study assessed the cost of bringing patients with type 2 diabetes to three clinically relevant endpoints with semaglutide versus sitagliptin and dulaglutide in Spain . - pubmed
METHODS : The proportions of patients achieving endpoints of HbA1c < 7.0 % , HbA1c < 7.0 % without hypoglycemia and without weight gain , and a > = 1.0 % HbA1c reduction with > = 5.0 % weight loss were taken from SUSTAIN 2 and 7 . - pubmed
The largest increase was found in miR-125a in the FXS sample , and the miR-125a levels were increased in two independent sets of urine samples from a total of 19 FXS children . - pubmed
The Panther Fusion respiratory panels consist of 3 separate multiplex assays that test for 1 ) influenza A , influenza B , and RSV ; 2 ) parainfluenza virus types 1 - 4 ; or 3 ) adenovirus , human metapneumovirus , and rhinovirus . - pubmed
A paradigm shift is underway from the current focus of drug development targeting the pathogen , to advancing cellular Host - Directed Therapies ( HDTs ) for tackling the aberrant host immune and inflammatory responses which underlie the pathogenesis of SARS - CoV-2 and high COVID-19 mortality rates . - pubmed
Background : We aim to evaluate the speed and rates of reperfusion in tandem large vessel occlusion acute stroke patients undergoing upfront cervical lesion treatment ( Neck - First : angioplasty and/or stent before thrombectomy ) as compared to direct intracranial occlusion therapy ( Head - First ) in a large international multicenter cohort . - pubmed
Results : In total , 289 patients with tandem atherosclerotic etiology were included in the analysis ( 182 Neck - First and 107 Head - First patients ) . - pubmed
Conclusions : The upfront approach of the intracranial lesion in patients with tandem large vessel occlusion strokes leads to similar reperfusion rates but faster reperfusion as compared to initial cervical revascularization followed by mechanical thrombectomy . - pubmed
METHODS : Paired cancerous and pre - cancerous tissues surgically resected from EC patients were collected in this study . - pubmed
: The leaves of Bersama abyssinica are used for the treatment of diabetes mellitus in folk medicine system of Ethiopia . - pubmed
The present study was done based on the traditional claim of B abyssinica for the treatment of diabetes mellitus . - pubmed
Blood glucose lowering activity of the extracts was studied in 4 animal models ; normoglycemic , oral glucose loaded , and streptozotocin - induced diabetic mice models . - pubmed
The crude extract at doses of 200 , and 400 mg / kg showed significant ( P < .05 ) hypoglycemic activity in normoglycemic mice . - pubmed
Background : Fatigue and insomnia are common symptoms experienced by breast cancer patients undergoing adjuvant radiation therapy ( RT ) , yet the underlying mechanisms of these symptoms are unclear . - pubmed
Methods : Breast cancer patients ( n = 147 ) completed questionnaires to longitudinally assess symptoms before , during , and after adjuvant RT . - pubmed
Carbon tetrachloride ( CCl4 ) was applied to create a mouse liver fibrosis model . - pubmed
Trabectedin Plus Radiotherapy for Advanced Soft - Tissue Sarcoma : Experience in Forty Patients Treated at a Sarcoma Reference Center . - pubmed
Symptomatic control and tumoral shrinkage is an unmet need in advanced soft - tissue sarcoma ( STS ) patients beyond first - line . - pubmed
We retrospectively reviewed advanced sarcoma patients treated with trabectedin concomitantly with radiotherapy with palliative intent . - pubmed
The combination of trabectedin plus radiotherapy is an active therapeutic option in patients with advanced STS , especially when tumor shrinkage for symptomatic relief is needed . - pubmed
Background : The Acupuncture Trialists ' Collaboration has updated its individual patient data meta - analysis of acupuncture for chronic pain originally published in 2012 . - pubmed
Two out of four HCV+ donors were viremic at the time of explantation . - pubmed
Purpose : To evaluate the predominant pathogens and clinical course in pediatric patients with orbital cellulitis ( OC ) complicated by subperiosteal abscess ( SPA ) . - pubmed
Methods : This is a single - center retrospective chart review evaluating pediatric patients with OC complicated by SPA treated at a tertiary care center in the Pacific Northwest . - pubmed
Results : Twenty - seven children were identified with OC complicated by SPA and bacterial cultures drawn . - pubmed
Pediatric patients with SAG infections required more surgery than children without this isolate , 100 % and 65 % , respectively ( p = .030 ) . - pubmed
BACKGROUND : Patients with human papillomavirus - related oropharyngeal cancers have excellent outcomes but experience clinically significant toxicities when treated with standard chemoradiotherapy ( 70 Gy ) . - pubmed
METHODS : In 19 patients , pre- and intratreatment dynamic fluorine-18 - labeled fluoromisonidazole positron emission tomography ( PET ) was used to assess tumor hypoxia . - pubmed
Patients without hypoxia at baseline or intratreatment received 30 Gy ; patients with persistent hypoxia received 70 Gy . - pubmed
RESULTS : Fifteen of 19 patients had no hypoxia on baseline PET or resolution on intratreatment PET and were deescalated to 30 Gy . - pubmed
Infection with mycobacterium kansasli and cryptococcus neoformans . - pubmed
EEG , regional cerebral blood flow ( rCBF ) and neuropathological autopsy data were studied in 17 patients with presenile dementia . - pubmed
In contrast , the Pick ( DFT ) patients had normal EEGs which remained so even late in the course when the signs of dementia were marked . - pubmed
( some comments on their relation with human eosinophilic granuloma ) ( author 's transl ) ] . - pubmed
Prostaglandins in cerebrospinal fluid of patients during various infectious diseases . - pubmed
In accord with the results of animal experiments prostaglandins of the E series seem to act as mediators of fever during infectious diseases also in man . - pubmed
This study demonstrated that treatment aiming at reducing the subgingival bacterial mass and suppressing the anaerobic segment had a beneficial effect in patients suffering from peri - implantitis . - pubmed
Because further immunosuppression would predispose the transplant patient to other opportunistic infections , we advocate a trial of plasmapheresis in the treatment of Guillain - Barre syndrome in this population . - pubmed
Postnatal behavioral development in methylazoxymethanol - induced microcephalic rats -- a behavioral teratology study . - pubmed
Behavioral testings in methylazoxymethanol ( MAM)-induced microcephalic rats were conducted . - pubmed
Maudsley reactive ( MR ) and nonreactive ( MNRA ) and Sprague - Dawley ( SD ) male rats were tested for their immobility response in the forced swim test when the water was fresh or soiled by a rat of the same or other strain . - pubmed
For all strains , rats tested in soiled water were less immobile than rats in fresh water . - pubmed
The interpretation of these findings regarding the use of the Maudsley rat strains as an animal model for studying anxiety and/or depression is discussed . - pubmed
Effects of guanethidine on sensitization to natural stimuli and self - mutilating behaviour in rats with a peripheral neuropathy . - pubmed
In the present study we have used a recent rat model for neuropathic pain to investigate the effect of the sympatholytic drug guanethidine on changes in behavioural responses evoked by mechanical , heat and cold stimuli and on self - mutilating behaviour . - pubmed
After a unilateral peripheral mononeuropathy induced by ligatures around the right common sciatic nerve , the left side receiving just a sham wound , lesioned and non - operated control animals were treated with saline or guanethidine ( 30 mg / kg ) for 4 consecutive days commencing 5 days before or 10 days after surgery . - pubmed
PURPOSE : To investigate the effects of chronic subcutaneous administration of reserpine ( Res ) or propranolol ( Prop ) on the postinfarction myocardial hypertrophy and the effects of Prop treatment on myocardial contractility in rats . - pubmed
METHODS : Male albino rats ( 3 - month - old ) were submitted to left coronary artery ligation to produce myocardial infarction . - pubmed
Comparison of management outcome of primary and secondary referred patients with traumatic extradural haematoma in a neurosurgical unit . - pubmed
A total of 104 patients with a traumatic extradural haematoma in a 5 - year period were studied . - pubmed
This better result was associated with a shorter delay between the time of conscious level deterioration and decompressive operation : 0.7 + /- 1.0 h vs 3.2 + /- 0.5 h. Direct admission of all head injured patients to a neurosurgical unit resulted in significant reduction in mortality and morbidity in patients with an extradural haematoma . - pubmed
in 6 patients , in 5 it was terminated early because of typical signs of clinical hypoglycaemia . - pubmed
The course of the blood sugar curves revealed differences between patients from abrupt drops of hyperglycaemic values to hypoglycaemia to balanced low blood sugar levels . - pubmed
The danger of early hypoglycaemia within 60 minutes was recorded only in patients with a known history of severe hypoglycaemic states . - pubmed
The authors described 2 patients with spinal tuberculosis . - pubmed
Staphylococcus aureus nasal carriage and infection in patients on continuous ambulatory peritoneal dialysis . - pubmed
We studied 140 consecutive patients beginning continuous ambulatory peritoneal dialysis ( CAPD ) at one of seven hospitals to assess the relation of the nasal carriage of Staphylococcus aureus to subsequent catheter - exit - site infection or peritonitis . - pubmed
The rates of peritonitis of all bacterial types did not differ significantly between the groups , but all 11 episodes of peritonitis caused by S. - pubmed
The patient presented without hypercalcemia , or urinary infection , or renal tubular acidosis , or ureteral obstruction , or ingestion of antacids , or metabolic disease , or previous graft lithiasis . - pubmed
A multifocal outbreak of hepatitis A traced to commercially distributed lettuce . - pubmed
Case - control studies of patrons of two of these restaurants found that eating green salad was strongly associated with acquiring hepatitis A : OR = 11.6 and OR = 4.4 . - pubmed
A 37 - year - old woman with diagnosis of thalassemia intermedia was admitted because of mild dyspnea and edema of her lower extremities . - pubmed
Prevention of autoimmune damage to islet grafts in BB rats by antibody therapy . - pubmed
One hundred and twenty - four patients had a postanal repair for the treatment of faecal incontinence between January 1976 and July 1987 . - pubmed
Incontinence was improved in 81 per cent of patients . - pubmed
Thirty patients with long - standing ( mean 30 days ) type I atrial flutter ( AF ) were treated with overdrive atrial pacing . - pubmed
Pacing was performed from a mean number of 2.1 sites per patient in Group A , 1.2 in B and 2.0 in C. Atrial fibrillation occurred in 7 , 3 and 4 patients , respectively . - pubmed
Acceleration of atrial flutter to a faster form of AF occurred in 3 , 3 and 4 patients , respectively . - pubmed
The administration of DISO is beneficial when overdrive atrial pacing is performed for the treatment of long standing AF in patients with organic heart disease . - pubmed
Perinatal outcomes of these pregnancies were compared with perinatal outcomes of a matched group of obstetric patients with no history or evidence of substance abuse ( group 3 [ N = 40 ] ) . - pubmed
Group 2 women had an increased rate of preterm delivery and low - birth - weight infants as well as an increased rate of intrauterine growth retardation . - pubmed
The protection afforded by the inhaled muscarinic cholinergic antagonist , ipratropium bromide ( IB ) 1 mg , from bronchoconstriction induced by inhaled adenosine was compared with that of methacholine in 8 allergic asthmatic subjects . - pubmed
The authors relate the case of two patients of 61 and 64 years old , each one having a high latero - cervical tumor , arching the soft palate , developed from the right vagus nerve and which was a chromaffin paraganglioma . - pubmed
Anismus , or constipation due to functional obstruction at the pelvic outlet by paradoxical contraction of the striated sphincter muscles during defaecation straining , is described in ten constipated patients and four patients with Parkinson ' s disease and constipation . - pubmed
A case of multiple intracranial arterial aneurysms occurring in a 43 year - old patient with an 8 - year history of Behcet ' s disease is reported . - pubmed
Decrease in number of hippocampal gamma - aminobutyric acid ( GABA ) immunoreactive cells in the rat kindling model of epilepsy . - pubmed
[ Human parasitosis in Mexico ] . - pubmed
Myocardial involvement in progressive muscular dystrophy of the Duchenne type was evaluated in 19 patients using thallium-201 myocardial perfusion imaging . - pubmed
Extensive perfusion defects were shown in 2 patients who died of congestive heart failure 1 to 2 years after the scintigraphic study . - pubmed
Increased renal carcinogenesis by dimethyl nitrosamine in protein deficient rats . - pubmed
Diacytosis of 125I - asialoorosomucoid by rat hepatocytes . - pubmed
Eighty - one patients with rosacea were treated with either I% metronidazole cream or the cream base as a placebo for two months . - pubmed
The first case of haemolytic anaemia with thrombocytopenia and acute renal failure induced by ingestion of aspirin in a 22 - year old woman is reported . - pubmed
In addition , the allergic nature of the patient 's hypersensitivity to aspirin was confirmed by positive lymphocyte transformation and basophil degranulation tests in the presence of the drug . - pubmed
Body weights were not changed by either treatment , although they were greater for the CD broilers than for the SAD broilers . - pubmed
Aberrations in T - cell subpopulations in patients with psoriasis and psoriatic arthritis . - pubmed
Peripheral blood T - cell subpopulations and B - cell numbers from 25 patients with uncomplicated psoriasis and 22 patients with psoriatic arthritis were compared with those of 24 age- and sex - matched healthy volunteers and 11 patients with radiologically defined erosive osteoarthritis . - pubmed
The numbers of early and late rosettes were found to be reduced in patients with psoriasis , with and without arthritis , while the total T - cell population ( measured by aminoethylthiouronium bromide - rosettes ) was found to be normal . - pubmed
There was no difference in the number of B cells between psoriatic patients and controls . - pubmed
The pokeweed mitogen response , however , was reduced in patients with cutaneous psoriasis and increased in patients with psoriatic arthritis . - pubmed
These studies further support the concept of an immunologic imbalance in lymphocyte populations from patients with psoriasis and psoriatic arthritis . - pubmed
Haematological and rheological ( plasma and serum viscosity , whole blood viscosity , and erythrocyte filterability ) factors were studied in 31 age - sex matched pairs of patients with sickle cell haemoglobin C disease with and without proliferative sickle retinopathy ( PSR ) . - pubmed
Growth , food intake , motor activity and experimental cardiac necrosis in early malnourished male rats . - pubmed
Male rats with protein energy malnutrition from birth to the 49th day of life ( PEM ) and then receiving normal diet ad libitum had lower body weights and relatively higher food intakes ( g/100 g body weight ) than controls ( C ) . - pubmed
the cardiac damage was smaller in previously malnourished animals ( PEM ) . - pubmed
The administration of dibekacine to 10 newborn carriers of a germ infection -- or staphylococcus , was controlled for auditory tolerance . - pubmed
Sequential femoropopliteal - tibial grafts have been advocated as a promising treatment for use in patients with severe ischemia of the distal lower extremity . - pubmed
M - mode and two - dimensional parasternal long axis view echocardiography , and left anterior oblique cineangiography were employed to assess the left ventricular wall motion in 10 normal subjects ( N ) and in 25 patients with hypertrophic cardiomyopathy : 7 patients with symmetric hypertrophy ( SH ) and 6 patients with apical cardiomyopathy ( AHCM ) and no intraventricular gradient ; 12 patients with hypertrophic obstructive cardiomyopathy and asymmetric septal hypertrophy with resting intraventricular gradient ( 6 pts ) ( HOCM - R ) or gradient occurring only after isoproterenol infusion ( 6 pts ) ( HOCM - I ) . - pubmed
The histories of two patients with restrictive ophthalmopathy are reported in whom the initial diagnosis was delayed primarily due to the relatively acute onset . - pubmed
The uptake of mercury in the species investigated varied considerably , being highest in the two strains of mice , followed by rat and hamster , and lowest in the guinea - pig . - pubmed
The two strains of mice were exposed to a wide range of mercury concentrations in air ( 0.002 - 3.5 mg / m3 ) . - pubmed
In acatalasemic mice the mercury content in liver was higher at all concentrations investigated , whereas in brain no difference between the two strains was found . - pubmed
Serum antibodies to hepatitis C virus ( HCV ) were tested for inpatients undergoing allogeneic BMT to determine the risk of acquiring HCV infection and the role of HCV in posttransplant liver complications . - pubmed
Before screening for non - A , non - B hepatitis , 14 % of the patients seroconverted to HCV ( 0.44 % per unit transfused ) . - pubmed
Positive anti - HCV status before and after BMT was not predictive of veno - occlusive disease , liver graft - versus - host disease ( GVHD ) , or death due to liver dysfunction . - pubmed
Group 1 comprised 27 patients ( seven with gastric ulcers , 14 with duodenal ulcers and six with gastritis ) treated with a combination of clarithromycin ( 200 mg , three times a day ) + sofalcone ( 100 mg , three times a day ) for 3 weeks . - pubmed
Group 2 comprised 15 patients with chronic active gastritis treated with the same doses of clarithromycin + sofalcone but for only 2 weeks ( group 2 ) . - pubmed
In these patients , significant improvements were seen in the gastritis score ( P & lt ; 0.025 ) , the index of periodic acid - Schiff - positive substances in the antral mucosa ( P & lt ; 0.025 ) and the ammonia concentration in gastric secretions ( P & lt ; 0.02 ) after treatment . - pubmed
[ Recovery of Staphylococcus aureus after acid injury in milk products ] . - pubmed
To determine the extent to which resorption contributes to the relative loss of bone during skeletal unloading of the growing rat and to explore potential means of preventing such bone loss , 0.1 mg P / kg alendronate was administered to rats before unloading of the hindquarters . - pubmed
Detection of Muerto Canyon virus RNA in peripheral blood mononuclear cells from patients with hantavirus pulmonary syndrome . - pubmed
Extrapulmonary thoracic disease caused by Blastomyces dermatitidis . - pubmed
A gene library constructed from large ( approximately 20 kb ) fragments of total DNA from the geldananmycin - producing strain Streptomyces hygroscopicus 3602 cloned in the plasmid vector pIJ61 were used to transform S. - pubmed
Three transformants of about 800 tested were found to have acquired the ability to produce an antibiotic lethal to a geldanamycin - sensitive strain of Bacillus subtilis . - pubmed
Prevalence of Helicobacter pylori infection and its effect on symptoms and non - steroidal anti - inflammatory drug induced gastrointestinal damage in patients with rheumatoid arthritis . - pubmed
Non - steroidal anti - inflammatory drugs ( NSAIDs ) and Helicobacter ( H pylori ) are both associated with an increased risk of peptic ulceration and gastropathy . - pubmed
Fifty two patients with rheumatoid arthritis requiring longterm NSAID treatment were studied . - pubmed
Patients with H pylori infection ( n = 26 ) had a higher dyspeptic symptom score ( p & lt ; 0.05 ) . - pubmed
In mismatch repair - deficient yeast strains , simple repeats are very unstable . - pubmed
Liver tumors were the most frequently observed neoplasms in these exposed dogs and included 7 primary hepatic hemangiosarcomas , 1 cholangiocarcinoma , 1 hepatocellular carcinoma , 1 fibrosarcoma , 4 biliary cystadenomas , and 1 fibroma . - pubmed
The morphologic features of the hemangiosarcomas and associated hepatic lesions were similar to those described for hemangiosarcomas induced in people exposed to Thorotrast . - pubmed
Human colon tumours usually form more prostaglandins ( PGs ) than associated normal tissues , but the mechanism(s ) are not fully understood . - pubmed
It is assumed that most cases of nosocomial diarrhea are due to Clostridium difficile because of the widespread use of broad - spectrum antibiotic agents . - pubmed
In a total of 20 patients with persistent hemodynamic depression despite mechanical ventilation plus dopamine ( 10 - 12 micrograms / kg / min ) and nitroglycerin ( 33 micrograms / min ) infusions additional therapy with dobutamine ( maximal dose : 9 micrograms / kg / min ; n = 10 ) or milrinone ( 0.5 microgram / kg / min ; n = 10 ) was started . - pubmed
After 16 months facial and auriculotemporal nerve function was assessed and the patient 's estimation of the scar was registered . - pubmed
Five percent of the patients had transient facial nerve weakness . - pubmed
Auriculotemporal nerve weakness was reported by 34 % of the patients . - pubmed
None of the patients found the scars disfiguring . - pubmed
In vivo electrically mediated protein and gene transfer in murine melanoma . - pubmed
We show that efficient permeabilization of murine melanoma can be obtained in vivo by applying electric pulses . - pubmed
We studied aspects of cell - matrix interaction of myocytes in an esophagogastrectomy specimen from a 12 - year - old patient with DL . - pubmed
Another group of animals was irradiated under the same conditions but , for radioprotective purposes , were also in deep hypothermia during radiation exposure . - pubmed
In the upper jaws of the animals exposed to irradiation , the Se concentration was significantly lower than in those irradiated under conditions of hypothermia ( p & lt ; 0.05 ) , although both groups showed no significant difference in Se concentration when compared to nonirradiated controls . - pubmed
In the lower jaws , the concentration of Se was significantly reduced in the irradiated group when compared with controls and the rats irradiated under conditions of hypothermia ( p & lt ; 0.05 ) . - pubmed
There was no significant difference in Se concentration between rats irradiated under conditions of hypothermia and nonirradiated controls . - pubmed
There was no significant change in Se concentration in the jaws of the rats protected by hypothermia during radiation exposure compared with nonirradiated controls . - pubmed
Pharmacokinetic and pharmacodynamic variations of acenocoumarol orally administrated either once or twice daily in patients with deep venous thrombosis . - pubmed
Antihepatotoxic potential of Trianthema portulacastrum in carbon tetrachloride - induced chronic hepatocellular injury in mice : reflection in haematological , histological and biochemical characteristics . - pubmed
The effect of an ethanolic extract of the plant Trianthema portulacastrum L. on the CCl4 - induced chronic hepatocellular damage of Swiss albino mice has been investigated . - pubmed
We also observed the dose - dependent antihepatotoxic effect of the extraction on these mice . - pubmed
Novel hypotensive agents from Verbesina caracasana . - pubmed
Caracasandiamide , a second hypotensive agent isolated from Verbesina caracasana , is the cyclobutane dimer ( truxinic type ) of the previously reported 1 -[( 3 , 4 - dimethoxycinnamoyl ) amino ]- 4 -[( 3 - methyl-2 - butenyl ) guanidino ] butane ( caracasanamide ) ( Delle Monache , G. ; et al . - pubmed
Caracasandiamide , assayed by the iv route in anesthetized rats at doses ranging from 50 to 3200 microgram / kg of body weight , was found to have no appreciable effect on heart rate . - pubmed
This retrospective review examined the cause , level of pathology , onset of symptoms , time taken to treatment , and outcome of 19 patients with cauda equina syndrome ( CES ) . - pubmed
Bladder dysfunction was observed in 19/19 patients , with 12/19 regarded as having significant impairment . - pubmed
Of the five patients identified as having a poor overall outcome , all five presented with a significant sphincter disturbance and 4/5 were left with residual sphincter dysfunction . - pubmed
Value of the lymphoblastic transformation in patients with silicosis . - pubmed
A 55 - year - old man with diabetes mellitus was sick with shivering , abdominal pain and Escherichia coli in blood and urine cultures ; a 40 - year - old woman with asthmatic bronchitis had abdominal pain and anaemia . - pubmed
In the woman , a calculus obstructed the pyelo - ureteral passage ; the resected kidney contained a squamous cell carcinoma . - pubmed
The condition is observed mostly in patients with diabetes mellitus or obstruction of the urinary tract . - pubmed
[ Identification of Escherichia coli and coliforms in childhood urinary sepsis using CROMOCEN CC chromogenic - fluorogenic medium ] . - pubmed
In the last few years , the use of chromogenic and fluorogenic reactions for the identification of the most important pathogens in human urinary tract infections has became a powerful tool in clinic diagnostic . - pubmed
Inactivation of the human androgen receptor gene is associated with CpG hypermethylation in uterine endometrial cancer . - pubmed
Impaired endothelium - dependent vasodilatation in renal failure in humans . - pubmed
BACKGROUND : The main causes of death in patients with chronic renal failure ( CRF ) are cardiovascular complications . - pubmed
The aim of the present study was to compare endothelium - dependent vasodilatation ( EDV ) in patients with chronic renal failure with a control population controlling for hypertension , diabetes mellitus and hypercholesterolaemia . - pubmed
METHODS : Fifty - six patients with moderate CRF ( mean creatinine clearance 29.4 ml / min/1.73 m(2 ) ) underwent evaluation of EDV and endothelium - independent vasodilatation ( EIDV ) by means of forearm blood flow ( FBF ) measurements with venous occlusion plethysmography during local intra - arterial infusions of methacholine ( Mch , 2 and 4 microg / min evaluating EDV ) and sodium nitroprusside ( SNP , 5 and 10 microg / min evaluating EIDV ) . - pubmed
Fifty - six control subjects without renal impairment underwent the same investigation . - pubmed
RESULTS : Infusion of Mch increased FBF significantly less in patients with renal failure than in controls ( 198 vs 374 % , P<0.001 ) , whereas no significant difference was seen regarding the vasodilatation induced by SNP ( 278 vs 269 % ) . - pubmed
CONCLUSIONS : Patients with moderate CRF have an impaired EDV even after correction for traditional cardiovascular risk factors and this impairment is related to the degree of renal failure . - pubmed
Plasmodium malariae -- a case of quartan malaria in Assam . - pubmed
Recent clinical results on patients treated with beta - emitting 32P stents suggest that radiation reduces in - stent restenosis but may exacerbate neointimal growth at the edges of the stents . - pubmed
We set up a randomized , double - blind , placebo - controlled trial to study the effectiveness of a topical corticosteroid agent -- fluticasone propionate aqueous nasal spray ( FPANS ) in patients with CRS . - pubmed
Mycobacterium avium subspecies paratuberculosis is a cause of Crohn ' s disease . - pubmed
The administration of many chemo - radiotherapy regimens in patients with cancer may be complicated by toxicities that limit the clinicians ' abilities to deliver the most effective doses of active agents . - pubmed
Oral mucositis is a major dose - limiting toxic effect and the most important cause of morbidity in patients undergoing chemo - radiotherapy for head and neck cancers , in patients undergoing bone marrow transplantation and those receiving certain chemotherapeutic agents for a variety of human malignancies . - pubmed
The intent of this paper is to review preventive strategies and treatment approaches for patients with established oral mucositis . - pubmed
Current studies and our increasing understanding of the etiology and pathogenesis of oral mucositis will lead to new approaches to the management and improved quality of life for these patients . - pubmed
[ Doppler investigation of blood flow in uterine vessels of patients with endometrial cancer ] . - pubmed
BACKGROUND : Sotalol is used in certain pediatric patients to treat , suppress , or prevent the recurrence of life - threatening ventricular arrhythmias . - pubmed
Human functional magnetic resonance imaging and magnetoencepholography data strongly suggest that aura is caused by cortical spreading depression . - pubmed
Mitochondrial dysfunction has been suggested by a low phosphocreatine : Pi ratio and a possible response by migraine patients to riboflavin prophylaxis . - pubmed
Inhalation exposure to methylene chloride does not induce systemic immunotoxicity in rats . - pubmed
Routine experience of the mouse - protection assay of pertussis vaccine . - pubmed
Experimental infection of the hemipteron Oncopeltus fasciatus with trypanosomatidae isolated from other hosts . - pubmed
After 110 months 83 % of patients had recurrence - free disease in M+ , whereas in M- only 40 % of patients were recurrence - free . - pubmed
[ Relation of asthenopia and some ophthalmological , neuropsychological , and musculoskeletal parameters in workers assigned to video display terminals ] . - pubmed
[ Treatment for hypertensive patients with diabetes mellitus ] . - pubmed
Diabetes mellitus doubles the risk of cardiovascular diseases , even in hypertensive patients who are already at high risk because of their high blood pressure . - pubmed
Of these patients , final pathology revealed focal nodular hyperplasia in 4 patients . - pubmed
The remaining 2 patients , who had adenoma , were found to harbor malignancy within the surgical specimens . - pubmed
In four clinical trials in mostly chemotherapy - naive patients with metastatic melanoma , paclitaxel was found to be effective with a response rate of 16 % . - pubmed
In vitro studies have shown that following exposure of cancer cells to paclitaxel for 1 h , sensitivity to repeat paclitaxel doses decreased markedly at 48 - 72 h and returned at 120 h. In this phase II study we assessed the efficacy of paclitaxel at a dose of 90 mg / m per day given intravenously over 80 min on days 1 , 5 and 9 every 3 weeks , initially in two groups of 14 patients with metastatic choroidal and non - choroidal melanoma . - pubmed
One patient in the non - choroidal melanoma group had a confirmed response , and 23 additional patients were therefore accrued to this group . - pubmed
We observed & gt;50 % tumour regression in six patients . - pubmed
All the responses except one were amongst the 32 evaluable patients with non - choroidal melanoma . - pubmed
OBJECTIVE : We aimed at investigating the relationship between Helicobacter pylori infection and in vivo lipid peroxidation and platelet activation , as reflected by urinary 8 - iso - prostaglandin ( PG ) F ( 2alpha ) and 11 - dehydro - thromboxane ( TX ) B2 , respectively , in otherwise healthy dyspeptic subjects . - pubmed
METHODS AND RESULTS : We measured urinary 8 - iso - PGF2alpha and 11 - dehydro - TXB2 excretion in 40 dyspeptic subjects with a positive 13C - urea breath test and 38 dyspeptic individuals with a negative test . - pubmed
The arterial circle of Willis of the mouse helps to decipher secrets of cerebral vascular accidents in the human . - pubmed
Thus , it is conceivable that the human tendency to develop cerebral vascular accidents ( CVAs ) might represent a disease of hominization . - pubmed
Thus , anatomical findings and possibly functions of the arterial circle of Willi may vary from one species to another , depending on one 's specific cerebral evolution . - pubmed
Indirect voiding urosonography for detecting vesicoureteral reflux in children . - pubmed
Among 57 children ( 45 girls and 12 boys , aged 2.7 to 12.0 years ) admitted for echo - enhanced VUS either as part of routine evaluation after urinary tract infection ( UTI ) or follow - up of a previously detected VUR , IVUS was also successfully performed in 47 children . - pubmed
METHODS AND RESULTS : Five strains of Bifidobacterium were analysed for their carbohydrate preference from 12 substrates . - pubmed
In vitro characterization of the human biotransformation pathways of aplidine , a novel marine anti - cancer drug . - pubmed
Analysis of fertility indices of cows with reproductive disorders and of normal cows in herds with low and normal fertility . - pubmed
In 16,910 cows , conception rates to first AI in cows with reproductive disorder were & gt;50 % below those in normal cows ( P<0.001 ) . - pubmed
Since a sizeable percentage of normal cows can be identified , reproducing normally under identical management conditions , cows in both kinds of herds with reproductive disorder must be less resistant to environmental stress . - pubmed
Thus , while cows with reproductive disorders maintained their general health and their high level of productivity , they responded either immediately with uterine disturbances or they refused to cycle properly , and they conceived later . - pubmed
In vivo imaging of hepatic fatty acid metabolism in patients with non - alcoholic steatohepatitis using semiquantitative 123I - labeled branched - chain fatty acid analog . - pubmed
Rats were pre - exposed to the footshock chamber ( context ) and shock stimulus was used unconditioned stimulus . - pubmed
During re - exposure to context , conditioned rats spent 80 % of the session in freezing while non - conditioned rats ( no shock group ) spent less than 15 % of the session time in freezing . - pubmed
METHODS AND MATERIALS : Between January 2001 and February 2006 , 59 patients with locally advanced or unfavorably located choroidal melanoma were enrolled in a Phase I / II clinical trial of carbon - ion radiotherapy at the National Institute of Radiologic Sciences . - pubmed
The primary endpoint of this study was normal tissue morbidity , and secondary endpoints were local tumor control and patient survival . - pubmed
RESULTS : Twenty - three patients ( 40 % ) developed neovascular glaucoma , and three underwent enucleation for eye pain due to elevated intraocular pressure . - pubmed
Five patients had died at analysis , three of distant metastasis and two of concurrent disease . - pubmed
All but one patient , who developed marginal recurrence , were controlled locally . - pubmed
Six patients developed distant metastasis , five in the liver and one in the lung . - pubmed
The current study examined the potential benefits of self - generation on learning and memory in individuals with traumatic brain injury ( TBI ) and multiple sclerosis ( MS ) . - pubmed
Subjects consisted of 18 individuals with TBI and 31 individuals with clinically definite MS . - pubmed
METHODS : One hundred eighty - two ( 182 ) patients with DSM - IV bipolar I disorder were longitudinally investigated ( approximately 17 years duration of the illness ) with standardized instruments . - pubmed
According to that dominance , the patients were divided into three groups ( mood - dominated , schizo - affective - dominated , schizophreniform - dominated ) , and these groups were compared to each other at various levels . - pubmed
Here we describe a 52 year old woman admitted with chest pain and ST elevation with mildly increased cardiac enzymes . - pubmed
The purpose of this study was to evaluate the size responses and vascular responses to three different sizes of Embosphere ( EMBS ) embolization particles used for chemo - embolization in patients with unresectable hepatocellular carcinoma ( HCC ) . - pubmed
Forty - seven patients with biopsy proven HCC treated with TACE using EMBS ( Biosphere Medical , Rockland , MA , USA ) were included in this study . - pubmed
We demonstrate the use of such an approach in estimating the number of people infected with the hepatitis C virus ( HCV ) in England and Wales . - pubmed
[ Light therapy : its effectiveness in treating insomnia in elderly patients ] . - pubmed
Cord blood - derived human MSCs were exposed to in vitro conditions simulating in vivo environments of the beating heart with acute ischemia , as follows : ( a ) myocardial proteins or serum obtained from sham - operated rats , and ( b ) myocardial proteins or serum from AMI rats , with or without application of oscillating pressure . - pubmed
The pathophysiologic significance of in vitro results was confirmed using the rat AMI model . - pubmed
Composting has been used for disposal of poultry carcasses and manure following outbreaks caused by avian influenza virus ( AIV ) and Newcastle disease virus ( NDV ) , but methods are needed to test for survival of the viruses in compost to ensure biosecurity . - pubmed
We have previously reported that 50 % of patients with sudden sensorineural hearing loss ( SNHL ) show high signals in the affected inner ear on 3D - FLAIR MRI . - pubmed
STUDY DESIGN AND METHODS : We used 3D - FLAIR at 3 Tesla with and without gadolinium enhancement to evaluate the pathologic conditions in the inner ears of 48 patients with sudden SNHL . - pubmed
RESULTS : Thirty - one of 48 patients with sudden SNHL showed high signals in the affected inner ear on precontrast 3D - FLAIR . - pubmed
In this case , we report on a pregnant woman who was diagnosed with non - small - cell lung cancer and received therapy with paclitaxel and cisplatin . - pubmed
METHODS : To study the formation of functional filtration bleb after trabeculectomy , the result of trabeculectomy with the limbus based conjunctival flap in 165 eyes and the fornix based conjunctival flap in 207 eyes ( 372 eyes in 372 cases with primary glaucoma in total ) was compared . - pubmed
In patients with trabeculectomy using the limbus based conjunctival flap , the success rate of the formation of the filtration bleb was 83.03 % in 1 week and 78.69 % in three months postoperatively , while in those using the fornix based conjunctival flap , the success rate was 55.07 % in 1 week and 53.03 % in 3 months . - pubmed
OBJECTIVE : To assess whether complementary and alternative medicine ( CAM ) use is associated with the timing of highly active antiretroviral therapy ( HAART ) initiation among human immunodeficiency virus ( HIV )- infected participants of the Women 's Interagency HIV Study . - pubmed
Prognostic significance of myocardial ischemia by dobutamine stress echocardiography in patients without angina pectoris after coronary revascularization . - pubmed
The clinical utility of stress testing in patients without angina pectoris after revascularization has been questioned . - pubmed
Idiopathic intracranial hypertension after 40 years of age : clinical features in 23 patients . - pubmed
The aim of this study is to investigate the clinical features of IIH in patients older than 40 years . - pubmed
METHODS : This is a retrospective chart review ( 1998 - 2007 ) of all consecutive patients older than 40 years who were diagnosed with IIH based on the Modified Dandy Criteria . - pubmed
RESULTS : Twenty three of the 200 IIH patients in the institutional database fulfilled study entry criteria . - pubmed
Coexisting systemic arterial hypertension was found in 13 ( 56.5 % ) patients . - pubmed
The most common presenting symptoms were visual ; mainly blurred vision and transient visual obscuration ( 15/17 patients , 88.23 % ) . - pubmed
Eleven patients ( 64.7 % ) complained of headache , and another 4 ( 23.5 % ) of pulsatile intracranial noise . - pubmed
Indoor allergen exposure to sources such as house - dust mites , pets , fungi , and insects plays a significant role in patients with allergic rhinitis and asthma . - pubmed
METHODS : A prospective double - blind randomised placebo - controlled crossover trial of phenylalanine - restricted diet was performed in a group of 34 adults ( aged 21 - 61 years , median 49 ) with late diagnosed PKU with severe challenging behaviour . - pubmed
Twenty years after the onset of diabetes , almost all patients with type 1 diabetes and over 60 % of patients with type 2 diabetes will have some degree of retinopathy . - pubmed
Predictors of nonresponse to lactulose for minimal hepatic encephalopathy in patients with cirrhosis . - pubmed
BACKGROUND / AIMS : Minimal hepatic encephalopathy ( MHE ) impairs health - related quality of life and predicts overt hepatic encephalopathy ( HE ) in cirrhotic patients . - pubmed
RESULTS : Sixty patients ( 54.5 % ) were diagnosed as having MHE : 17/39 ( 44 % ) in Child 's A , 21/42 ( 50 % ) Child 's B and 22/29 ( 76 % ) in Child 's C. There was a significant difference between Child 's C 's vs Child 's A 's and B 's ( P<0.05 ) . - pubmed
Of 60 patients with MHE , after treatment , psychometry remained abnormal in 22 ( 36.6 % ) and P300ERP in 21 ( 35 % ) patients . - pubmed
CONCLUSION : The prevalence of MHE was 55 % and MHE improved in 57 % patients with lactulose . - pubmed
BACKGROUND AND PURPOSE : Patients with chronic visual field defects typically show a contralesional line bisection error ( LBE ) . - pubmed
METHODS : Twenty - two patients with visual field defects due to stroke without neglect were tested for line bisection and for the anatomic lesion site by voxelwise lesion - behavior mapping analysis . - pubmed
RESULTS : Patients with visual field defects in the acute and chronic phases differed in neither the direction nor the extent of their LBE . - pubmed
INTRODUCTION : Conventional imaging ( CI ) is known to have limitations with respect to staging of patients with primary or relapsed prostate cancer . - pubmed
METHODS : Sixteen prostate cancer patients were evaluated ( 7 for staging and 9 for restaging ) . - pubmed
CONCLUSION : FCH - PET / CT has the potential to impact on the management of patients with prostate cancer significantly more often than CI . - pubmed
BACKGROUND : In patients with various autoimmune and rheumatic diseases , a drug - induced lupus - like syndrome ( DILS ) has been reported with the use of adalimumab , cerrolizumab pegol , etanercept , and infliximab . - pubmed
MATERIALS AND METHODS : We describe a 62 - year - old woman with rheumatoid arthritis who developed a pruritic photo - distributed rash two months after the initiation of etanercept therapy . - pubmed
RESULTS : In our study , all patients were having bilateral nasal polypi . - pubmed
A number of novel pyrrole [ 1,2 - a ] pyrazine derivatives were synthesized and evaluated in in vivo animal models of epilepsy . - pubmed
Obese men participated in an 8 - week low - intensity training program without concomitant diet . - pubmed
At baseline , obese men showed diastolic dysfunction on standard echocardiography , lower strain values ( systolic strain : 15.9 + - 0.9 vs. 18.8 + - 0.3 % , diastolic strain rate : 0.81 + - 0.09 vs. 1.05 + - 0.06 s(-1 ) ) , and significant intraventricular dyssynchrony ( systolic : 13.3 + - 2.1 vs. 5.4 + - 2.1 ms , diastolic : 17.4 + - 3.2 vs. 9.1 + - 2.1 ms ) ( P & lt ; 0.05 vs. controls for all variables ) . - pubmed
A randomized , double - blind , placebo - controlled pilot study to assess the ability of rifaximin to prevent recurrent diarrhoea in patients with Clostridium difficile infection . - pubmed
BACKGROUND : Uncontrolled case series have demonstrated decreased Clostridium difficile infection ( CDI ) recurrence in patients given rifaximin after standard antibiotic therapy . - pubmed
However , clinical trials assessing whether rifaximin decreases recurrent diarrhoea in patients with CDI have not been performed . - pubmed
The purpose of this study was to assess rates of recurrent diarrhoea in patients with CDI given rifaximin versus placebo immediately after standard therapy . - pubmed
Patients with CDI and a Horn 's index & gt;=1 were randomized to receive rifaximin 400 mg three times daily or placebo for 20 days given immediately after finishing standard anti - CDI antibiotics . - pubmed
Patients were followed for 3 months and assessed for recurrent diarrhoea that included CDI recurrence ( return of diarrhoea with a positive toxin test ) and patient self - reported return of non - CDI diarrhoea after a period of wellness . - pubmed
Recurrent diarrhoea occurred in 17 of 35 ( 49 % ) patients given placebo and 7 of 33 ( 21 % ) given rifaximin ( P = 0.018 ) . - pubmed
CDI recurrence occurred in 11 of 35 ( 31 % ) patients given placebo and 5 of 33 ( 15 % ) patients given rifaximin ( P = 0.11 ) . - pubmed
CONCLUSIONS : Patients with CDI given a rifaximin chaser regimen experienced a decreased incidence of recurrent diarrhoea compared with placebo . - pubmed
Effects of glutamine supplementation on oxidative stress - related gene expression and antioxidant properties in rats with streptozotocin - induced type 2 diabetes . - pubmed
These results suggest that dietary GLN supplementation decreases oxidative stress - related gene expression , increases the antioxidant potential and may consequently attenuate renal oxidative damage in rats with STZ - induced diabetes . - pubmed
BACKGROUND : There are no clear recommendations to guide posttreatment surveillance in patients with pancreatic cancer . - pubmed
Our goal was to describe the posttreatment surveillance patterns in patients undergoing curative - intent resection for pancreatic cancer . - pubmed
BACKGROUND : The cat , considered the main reservoir of Microsporum canis , lives in urban areas , and also plays an important role in the emergence of dermatomycoses . - pubmed
A total of 45 samples from cats with and without dermatological lesions were analysed . - pubmed
Mycoplasma hyosynoviae is a common agent responsible for polyarthritis leading to decreased production in swine herds worldwide . - pubmed
Antimicrobial agents are used to combat infections ; however breakpoints for M. - pubmed
A dry microbroth dilution method was conducted to compare the minimum inhibitory concentrations ( MICs ) for 18 antibiotics , representative of different classes , against 24 recent isolates ( 23 field isolates and the type strain ) of M. - pubmed
STUDY DESIGN AND SETTING : Prospective cohort study of 602 newly diagnosed prostate cancer patients recruited from an urban academic hospital and a Veterans Administration hospital . - pubmed
METHODS : Consecutive patients with high myopia ( & gt;=6 diopters [ D ] ) with no other pathology such as lacquer cracks in the fovea , choroidal neovascularization , or myopic macular schisis , were evaluated . - pubmed
RESULTS : The New York cohort was composed of 35 eyes of 25 patients who had a mean age of 57 years ( standard deviation , + -18.1 years ) and a mean refractive error of -10.9 D ( + -3.6 D ) . - pubmed
The Japanese cohort was composed of 110 eyes of 61 patients who had a mean age of 46.8 years ( + -14.7 years ) and a mean refractive error of -9.2 D ( + -3.1 D ) and a mean axial length of 27 mm ( + -1.4 mm ) . - pubmed
[ Late renal artery stent thrombosis treated with aspiration trombectomy in a patient with renal insufficiency and renal hypertension ] . - pubmed
METHODS AND RESULTS : A total of 652 patients with stable CAD were studied . - pubmed
RESULTS : During 1990 - 1991 , 14 538 children were identified with respiratory infections and bronchiolitis was diagnosed in 519/14 538 children ( 3.56 % ) . - pubmed
Tobacco use leads to numerous health problems , including cancer , heart disease , emphysema , and stroke . - pubmed
We report a case of multiple cutaneous atypical leiomyomas occurring in a 43 - year - old man with long history of lesions of the right lower leg and a family history of leiomyomatosis . - pubmed
Duration of antiresorptive effects of low - dose zoledronate in osteopenic postmenopausal women : a randomized , placebo - controlled trial . - pubmed
A total of 180 postmenopausal women with osteopenia enrolled in a double - blind , randomized , placebo - controlled trial over 2 years at an academic research center . - pubmed
Weight reduction improves nocturnal respiration in obese sleep apnoea patients - A randomized controlled pilot study . - pubmed
SUMMARY : OBJECTIVES : Randomized controlled pilot study of the effect of weight reduction on nocturnal respiratory parameters in obese patients with obstructive sleep apnoea syndrome ( OSAS ) . - pubmed
CONCLUSIONS : This pilot study indicates that weight reduction improves nocturnal respiration in obese OSAS patients after 3 months ' dietary treatment compared to expectancy . - pubmed
BACKGROUND : Over the past years , Q fever has become a major public health problem in the Netherlands , with a peak of 2,357 human cases in 2009 . - pubmed
In the first instance , Q fever was mainly a local problem of one province with a high density of large dairy goat farms , but in 2009 an alarming increase of Q fever cases was observed in adjacent provinces . - pubmed
RESULTS : Overall , public perceptions and behaviors regarding Q fever were consistent with the trends over time in the numbers of new human Q fever cases in different epidemiological regions and the amount of media attention focused on Q fever in the Netherlands . - pubmed
Preoperative pulmonary rehabilitation in patients with non - small cell lung cancer and chronic obstructive pulmonary disease . - pubmed
INTRODUCTION : The aim of this study was to assess the effects of preoperative pulmonary rehabilitation ( PPR ) on preoperative clinical status changes in patients with chronic obstructive pulmonary disease ( COPD ) and non - small cell lung cancer ( NSCLC ) , and net effects of PPR and cancer resection on residual pulmonary function and functional capacity . - pubmed
MATERIAL AND METHODS : This prospective single group study included 83 COPD patients ( 62 + -8 years , 85 % males , FEV1 = 1844 + -618 ml , Tiffeneau index = 54 + -9 % ) with NSCLC , on 2 - 4 - week PPR , before resection . - pubmed
CONCLUSIONS : Preoperative pulmonary rehabilitation significantly enhances clinical status of COPD patients before NSCLC resection . - pubmed
Subsequent testing of donations positive in Treponema pallidum hemagglutination assay included Venereal Disease Research Laboratory and fluorescent Treponemal antibody absorption . - pubmed
Coinfection with HIV , HCV , and HBV was calculated as 8 % , 1.88 % , and 0.37 % for positive donations , respectively . - pubmed
A 12 - year - old boy presented with a 6 - month history of hip pain . - pubmed
Tuberculosis in HIV patient . - pubmed
Bone metastases are often observed in patients with lung cancer , kidney cancer , breast cancer , myeloma , and prostate cancer . - pubmed
Autologous engineered skin substitutes ( ESS ) have been shown to close excised , full - thickness burns , but are consistently hypopigmented due to depletion of human melanocytes ( hM ) during culture of keratinocytes . - pubmed
To evaluate this risk , 16 strains of hM were isolated and propagated in selective culture medium , then injected subcutaneously into athymic mice ( 1 x 10(7 ) hM / animal ; n = 6 / strain ) and followed for 24 weeks . - pubmed
Human melanoma cells ( SK - Mel-2 , SK - Mel-5 ) served as positive controls . - pubmed
In contrast , SK - Mel-2 formed tumors in 50 % of mice , and SK - Mel-5 formed tumors in 83 % of mice . - pubmed
PURPOSE OF REVIEW : Cardiac patients are a fast emerging population vulnerable to gastrointestinal bleeding ( GIB ) due to their use of antithrombotic medications . - pubmed
This review will quantify the GIB risk of cardiac patients prescribed antithrombotic medications , summarize risk - management strategies and highlight knowledge gaps . - pubmed
We report that up to 49 of the 232 monogenic etiologies ( 21 % ) of human primary immunodeficiencies ( PIDs ) were initially reported in single patients . - pubmed
When supported by satisfaction of rigorous criteria , the report of single patient - based discovery of Mendelian disorders should be encouraged , as it can provide the first step in the understanding of a group of human diseases , thereby revealing crucial pathways underlying physiological and pathological processes . - pubmed
Yet , current treatments targeting serotonergic and noradrenaline reuptake systems are insufficient to provide long - term relief from depressive symptoms in most patients , indicating the need for new treatment targets . - pubmed
A sample from periodontal pocket was extracted to identify Porphyromonas gingivalis ( Pg ) , Treponema denticola ( Td ) , Tannerella forsythia ( Tf ) Prevotella intermedia ( Pi ) and Agreggatibacter actinomycemcomitans ( Aa ) . - pubmed
CLINICAL FEATURES : A 48 - year - old white man presented to a chiropractic clinic with a complaint of left lateral elbow pain that began 2 years previous with insidious onset . - pubmed
The patient reported an inability to play 18 consecutive holes of golf due to the pain . - pubmed
Significance of oral glucose tolerance tests in non - alcoholic fatty liver disease patients with a fasting plasma glucose level of & lt;126 mg / dL and HbA1c level of & lt;= 6.4 % in Japan . - pubmed
OBJECTIVE : The aim of this study was to clarify the indications for oral glucose tolerance tests ( OGTT ) in non - alcoholic fatty liver disease ( NAFLD ) subjects with a HbA1c level of & lt;=6.4 % , fasting plasma glucose ( FPG ) level of & lt;126 mg / dL and no history of diabetes . - pubmed
PATIENTS : A total of 569 NAFLD subjects underwent 75 - g OGTT . - pubmed
RESULTS : The prevalence of diabetes on the OGTT was 7.7 % ( 44/569 ) among the NAFLD patients with an HbA1c level of & lt;=6.4 % , FPG level of & lt;126 mg / dL and no history of diabetes . - pubmed
Factor structure and psychometric properties of the TFEQ in morbid obese patients , candidates to bariatric surgery . - pubmed
METHODS : Immune - activating properties of MPLA and LPS were compared in human monocytes and mast cells ( MCs ) , a mouse endotoxin shock model ( ESM ) , and mouse bone marrow ( BM)-derived myeloid dendritic cells ( mDCs ) , T cells ( TCs ) , B cells , and MCs . - pubmed
RESULTS : The most common clinical syndrome in these 42 patients was chronic cholecystitis , followed by acute cholecystitis . - pubmed
PURPOSE : In this phase I study , single - agent chemotherapy was conducted in patients with locoregionally advanced nasopharyngeal carcinoma ( NPC ) using nedaplatin ( NDP ) and concomitant radiotherapy . - pubmed
CONCLUSION : NDP combined with radiotherapy and administered every 21 days for three cycles was active in patients with locoregionally advanced NPC . - pubmed
METHODS : We identified 8427 patients in Surveillance , Epidemiology , and End Results ( SEER ) with nonmetastatic oropharyngeal cancer with unknown HPV - status diagnosed from 2004 to 2008 . - pubmed
We present two cases of congenital intrahepatic portosystemic shunts in which the right portal vein directly communicated with the inferior venacava ( IVC ) in one patient and with the hepatic vein in the other . - pubmed
Multiple hepatic nodules consistent with focal nodular hyperplasia ( FNH ) were seen in the first patient . - pubmed
The second patient presented with recurrent history of hepatic encephalopathy . - pubmed
Chemotherapy for Adults with Malignant Glioma : A Systematic Review and Network Meta - Analysis . - pubmed
To compare the efficacy of common therapies , we performed network meta - analysis to estimate the efficacy and safety among procarbazine , lomustine , vincristine , temozolomide , bevacizumab plus temozolomide , and placebo for patients with malignant glioma . - pubmed
The primary endpoint of the analysis was the overall survival ( OS ) and progression - free survival ( PFS ) of glioma patients . - pubmed
CONCLUSION : Bevacizumab plus temozolomide combination therapy is not significantly more effective than temozolomide alone in improving survival of glioma patients . - pubmed
Bevacizumab should be used with caution in glioma patients . - pubmed
EXPERT OPINION : Ospemifene is efficacious for improving vaginal dryness or dyspareunia as the patient - identified most bothersome symptom , and Phase III clinical trials ( 4648 patients ) have shown good efficacy in terms of improvement of objective and subjective signs and measures of GSM in postmenopausal women . - pubmed
A 67 - year - old man presented with labile hypertension and orthostatic hypotension after radical neck dissection and radiotherapy for squamus cell carcinoma . - pubmed
Our findings have implications for the use of mouse models to assess bone marrow toxicity for DNA - damaging agents and inhibitors of the DNA damage response . - pubmed
METHODS : A bioglue - coated Teflon sling was crafted by the surgeon and applied to patients in whom neurovascular compression was caused by the VA . - pubmed
Neither recurrence nor postoperative neurological deficit was noted during the 2 - year follow - up , except in one patient who developed permanent deafness . - pubmed
Parametrial involvement in women with low - risk , early - stage cervical cancer . - pubmed
This study identified the incidence of parametrial involvement in low risk , early - stage cervical cancer patients and evaluated the factors associated with parametrial involvement . - pubmed
Patients with squamous cell carcinoma or adenocarcinoma grade 1 - 2 , tumour size less than 2 cm , no lymphovascular space invasion ( LVSI ) , negative pelvic nodes and depth of stromal invasion ( DSI ) less than 10 mm were identified as the low - risk group . - pubmed
Most patients ( 81.5 % ) had tumour size less than 2 cm . - pubmed
Thirteen patients ( 5.3 % ) had parametrial involvement , 77 ( 31.7 % ) had DSI more than 10 mm , 121 ( 49.8 % ) had more than 50 % invasion , 119 ( 49 % ) had LVSI and 19 ( 7.5 % ) had node metastasis . - pubmed
A comparison with a matched population of patients with femoroacetabular impingement . - pubmed
PURPOSE : To prospectively compare defects of the articular cartilage and labrum in asymptomatic volunteers and in patients with femoroacetabular impingement ( FAI ) matched for age and gender . - pubmed
A total of 14 % of volunteers had acetabular cartilage defects , and 6 % had femoral cartilage defects , compared with 47 % and 30 % in symptomatic patients ( P & lt;= 0.001 and P & lt;= 0.003 ) , respectively . - pubmed
Labrum defects were seen in 44 % of volunteers versus 61 % of patients ( P & lt;= 0.12 ) . - pubmed
CONCLUSION : A substantial number of asymptomatic volunteers had labral tears , defects of the acetabular cartilage , and to a lesser degree , defects of the femoral cartilage ; our data demonstrate that not all cartilage and labral defects of the hip joint are symptomatic and that a similar predilection for location of defects is found in volunteers and FAI patients . - pubmed
Post - Anoxic Reticular Reflex Myoclonus in a Child and Proposed Classification of Post - Anoxic Myoclonus . - pubmed
PATIENT DESCRIPTION : A nine - year - old boy with severe hypoxic - ischemic encephalopathy due to submersion developed early epileptic spasms followed by stimulus sensitive multifocal generalized myoclonus and later dystonia . - pubmed
CONCLUSIONS : Reticular reflex myoclonus can be demonstrated by detailed neurophysiological assessment in children as in adults , and it has a similar poor prognosis in children . - pubmed
Aortoiliac occlusive disease ( AIOD ) is widely prevalent and leads to significant limitations in patient quality of life . - pubmed
hydrophila recovered from Nile tilapia exhibiting disease and mortality after exposed to transport - induced stress and subsequently confirmed their virulence in artificial infection . - pubmed
Experimental infection revealed that the high dose of A. - pubmed
Here , we present a 56 - year - old man with pancreatic SCC . - pubmed
However , routine vaccines for the world 's major human parasitic diseases do not yet exist . - pubmed
We performed a real - life study on topical therapies in psoriasis and observed a variation in the amounts of ointment patients applied during the study . - pubmed
CONCLUSIONS : We look forward to seeing whether the current pressure to improve psoriasis treatment leads to more patients receiving systemic therapies or to better adherence to , and persistence with , topical therapies . - pubmed
CONCLUSION : Metastatic , castration - resistant prostate cancer is a discrete and different phase of prostate cancer with newer agents that have shown great promise in controlling the disease and offering a survival benefit for patients . - pubmed
Venous invasion by hepatic tumors most commonly occurs with hepatocellular carcinoma and is associated with worse patient prognosis . - pubmed
Research has shown that the process of sensory gating is disrupted in patients suffering from clinical disorders including attention deficit hyper activity disorder , schizophrenia , and Alzheimer ' s disease . - pubmed
Infarct size were measured in isolated male Sprague - Dawley rat Langendorff perfused hearts treated for 125 min with Sunitinib in the presence and absence of NQDI-1 . - pubmed
Sunitinib significantly decreased the cell viability of human acute myeloid leukemia 60 cell line ( HL60 ) . - pubmed
METHODS : Eight - nine MDS patients(MDS group ) and 20 persons without hematologic disease as controls(Control group ) were enrolled . - pubmed
These findings may partially explain the cause of hematopoietic stem cell malignant clone in MDS patients . - pubmed
[ Analysis of effect of prevention and control technique training of human important parasitic diseases in Jiangsu Province in 2017 ] . - pubmed
OBJECTIVE : To evaluate the effect of the prevention and control technique training of human important parasitic diseases for basic professional and technical personnel in Jiangsu Province in 2017 . - pubmed
Patients in cardiogenic shock due to severe failure of a mitral bioprosthesis have extremely high risk for repeat standard cardiac surgery . - pubmed
We report a successful transseptal mitral valve - in - valve implant performed in a patient in cardiogenic shock due to a flail mitral bioprosthesis requiring bridging intravenous inotropic and intra - aortic balloon pump support . - pubmed
The aim of this study was two - fold : ( i ) to investigate structural and functional brain network architecture in patients with Alzheimer ' s disease ( AD ) and amnestic mild cognitive impairment ( aMCI ) , stratified in converters ( c - aMCI ) and non - converters ( nc - aMCI ) to AD ; and to assess the relationship between healthy brain network functional connectivity and the topography of brain atrophy in patients along the AD continuum . - pubmed
Ninety - four AD patients , 47 aMCI patients ( 25 c - aMCI within 36 months ) and 53 age- and sex - matched healthy controls were studied . - pubmed
Healthy topological features of brain regions were assessed based on their connectivity with the point of maximal atrophy ( epicenter ) in AD and aMCI patients . - pubmed
Brain network graph analysis properties were severely altered in AD patients . - pubmed
Brain regions most strongly connected with the disease - epicenter in the healthy functional connectome were also the most atrophic in both AD and c - aMCI patients . - pubmed
One - year optical coherence tomography findings in patients with late and very - late stent thrombosis treated with intravascular imaging guided percutaneous coronary intervention . - pubmed
Patients with late / very - late stent thrombosis ( ST ) are at high risk of recurrent - ST . - pubmed
None of the patients had thin - cap fibroatheroma neoatherosclerosis . - pubmed
This single center study aimed to characterize GIST patients in terms of tumor location , clinical presentation , metastasis formation , as well as associated secondary malignancies . - pubmed
METHODS : In a retrospective study , 104 patients with a histologically confirmed diagnosis of GIST , collected between 1993 and 2011 , were characterized for several clinical features . - pubmed
Although uncommon , congenital cardiac defects should be considered in animals presenting with clinical signs of hypoxemia , dyspnea , or failure to thrive . - pubmed
METHODS : All patients with SSc who underwent at least two 6MWT within a minimum 3 - month interval plus simultaneous routine clinical , biological , and functional evaluations were consecutively enrolled in this observational study over 6 years . - pubmed
CONCLUSION : We show strong reproducibility for the 6MWD and confirm the 6MWT utility to assess the overall prognosis of patients with SSc . - pubmed
Importantly , we find that distinctive dynamic connectivity patterns are spatially associated with Allen Human Brain Atlas genetic transcription levels of synaptic long - term potentiation and long - term depression - related genes . - pubmed
METHODS : 44 patients with congenital heart defect were enrolled in the study . - pubmed
Methods : In this double - blind , cluster - randomized trial , villages were randomly allocated ( 1:1 ) for high - coverage vaccination of children aged 6 months through 10 years with 2008 - 09 northern hemisphere IIV3 or inactivated polio vaccine ( IPV ) . - pubmed
Among vaccinees , total effectiveness against illness caused by seasonal influenza virus ( presumed all drifted A / H3N2 based on antigenic characterization data ) circulating at high rates among children was 43.6 % ( 95 % CI , 18.6 % to 60.9 % ) . - pubmed
Total effectiveness against illness caused by pandemic influenza virus ( A / H1N1pdm09 ) was -52.1 % ( 95 % CI , -177.2 % to 16.6 % ) . - pubmed
Conclusions : IIV3 provided statistically significant , moderate protection to children in Senegal against circulating pre-2010 seasonal influenza strains but not against A / H1N1pdm09 not included in the vaccine . - pubmed
METHODS : We performed a retrospective analysis of a prospectively held database of all patients who underwent arterial ligation for infected femoral pseudoaneurysms due to chronic intravenous drug abuse from January 2012 to March 2018 . - pubmed
Information recorded for each patient included age , gender , blood investigations , microbiologic results , diagnostic modality , operative details , outcome of surgery , postoperative complications , and follow - up . - pubmed
Nine patients underwent major limb amputation for severe limb ischemia ( 7 transfemoral amputations and two 53 hip disarticulation ) . - pubmed
ETHNOPHARMACOLOGICAL RELEVANCE : Copaiba oleoresin has been used in folk medicine in the treatment of bronchitis , syphilis , skin diseases and ulcers due to its anti - inflammatory and antiseptic activities , but there is no information about major compounds oral absorption to support the traditional use . - pubmed
Prevalence of cervical disease at age 20 after immunisation with bivalent HPV vaccine at age 12 - 13 in Scotland : retrospective population study . - pubmed
OBJECTIVE : To quantify the effect on cervical disease at age 20 years of immunisation with bivalent human papillomavirus ( HPV ) vaccine at age 12 - 13 years . - pubmed
CONCLUSIONS : Routine vaccination of girls aged 12 - 13 years with the bivalent HPV vaccine in Scotland has led to a dramatic reduction in preinvasive cervical disease . - pubmed
Development and validation of a real - time RT - PCR assay for the quantification of rabies virus as quality control of inactivated rabies vaccines . - pubmed
Elemental formula is commonly used in children with feeding intolerance . - pubmed
We describe two , medically complex and feeding tube dependent , patients exclusively fed with Neocate who subsequently developed hypophosphatemic rickets . - pubmed
Cervical cancer develops through persistent infection with high - risk human papilloma virus ( hrHPV ) and is a leading cause of death among women worldwide and in the United States . - pubmed
Periodic surveillance through hrHPV and Pap smear - based testing has remarkably reduced cervical cancer incidence worldwide and in the USA . - pubmed
BACKGROUND : Staphylococcus aureus remains a medical challenge in the treatment of bacterial infections . - pubmed
Pleomorphic xanthoastrocytoma ( PXA ) is an uncommon , long - term epilepsy associated tumor of young adults . - pubmed
Larger trials are required to understand long - term efficacy and safety of this medication in various patient populations and to elucidate its effect on the pathologic processes underpinning type 2 diabetes . - pubmed
The reinforcing effects of drugs mostly depend on dopamine signaling in the nucleus accumbens , and chronic drug exposure triggers glutamatergic - mediated neuroadaptations in dopamine striato - thalamo - cortical ( predominantly in prefrontal cortical regions including orbitofrontal cortex and anterior cingulate cortex ) and limbic pathways ( amygdala and hippocampus ) that , in vulnerable individuals , can result in addiction . - pubmed
Methods for generating hypotheses in human enteric illness outbreak investigations : a scoping review of the evidence . - pubmed
PATIENT CONCERNS : A 47 - year - old woman was admitted due to poor appetite , general fatigue , puffiness of face , systemic rash , and abdominal distension . - pubmed
On physical examination , the patient displayed as general lymphadenopathy , splenomegaly , hepatomegaly , and shifting dullness . - pubmed
Everolimus - associated cytomegalovirus colitis in a patient with metastasized breast cancer : a case report . - pubmed
PURPOSE : Anti - cancer therapy put patients in an immunocompromised status . - pubmed
METHODS : We present a case of everolimus - associated cytomegalovirus colitis on a patient receiving everolimus and exemestane therapy for the treatment of metastasized breast cancer . - pubmed
RESULTS : The patient presented septic shock and acute peritonitis at first . - pubmed
Thus , for solid cancer patients presented with fever of unknown origin , clinicians should consider potential complications of CMV infection . - pubmed
The most common adverse events were cataract / posterior subcapsular opacities in 47 ( 11.03 % ) patients and conjunctival hemorrhage in 24 ( 5.44 % ) patients . - pubmed
METHODS : Two 12 - week , Phase 3 , randomized , multicenter , double - blind , vehicle - controlled , 2 - arm studies were performed in patients with moderate - to - severe papulopustular rosacea . - pubmed
RESULTS : Subjects who received FMX103 1.5 % , vs vehicle - treated controls , exhibited a significantly greater reduction in the number of inflammatory lesions ( FX2016 - 11 : -17.57 vs -15.65 ; P=.0031 ; FX2016 - 12 : -18.54 vs -14.88 ; P<.0001 ) and higher rates of Investigator Global Assessment treatment success ( FX2016 - 11 : 52.1 % vs 43.0 % ; P=.0273 ; FX2016 - 12 : 49.1 % vs 39.0 % ; P=.0077 ) . - pubmed
Genetic improvement in banana is a challenging task due to its parthenocarpic nature and triploid genome . - pubmed
Inosine prevents hyperlocomotion in a ketamine - induced model of mania in rats . - pubmed
Evidence shows that individuals in manic episodes present a purinergic system dysfunction . - pubmed
Despite the limitations , inosine administration could be a promising candidate for bipolar disorder treatment , especially by attenuating maniac phase symptoms , once it was able to prevent the hyperlocomotion induced by ketamine in rats . - pubmed
ImPlementation REsearCh to DEvelop Interventions for People Living with HIV ( the PRECluDE consortium ): Combatting chronic disease comorbidities in HIV populations through implementation research . - pubmed
Buruli ulcer ( BU ) is a subcutaneous necrotic infection of the skin caused by Mycobacterium ulcerans . - pubmed
It is the third most common human mycobacterial disease after tuberculosis ( TB ) and leprosy . - pubmed
In addition , the high level of genetic polymorphism of different strains of N. - pubmed
METHODS : In this randomized trial with adult depressed outpatients ( n = 151 ) , we estimated Gaussian graphical models among nine core MDD symptom - domains before and after 8 weeks of treatment with either escitalopram or desvenlafaxine . - pubmed
KEY POINTS : Early detection and diagnosis of vertebral fragility fractures ( VFFs ) significantly reduce patient morbidity and mortality . - pubmed
Analysis of Risk Factors for Lymph Node Metastases in Elderly Patients with Papillary Thyroid Micro - Carcinoma . - pubmed
Methods : We retrospectively analyzed the clinical data of thyroid cancer patients admitted to the Head and Neck Surgery Center of Sichuan Cancer Hospital , Chengdu , China , from January 2015 to September 2018 . - pubmed
Conclusion : 1 ) Preoperative color Doppler ultrasound is not recommended as the basis for cervical lymph node dissection in PTMC patients . - pubmed
2 ) For multiple cancer foci , irregular nodules , and elderly patients with PTMC extra - thyroidal expansion , we recommend a prophylactic central lymph node dissecting . - pubmed
3 ) Nonsurgical observation of PTMC in elderly patients with low risk should be carefully selected . - pubmed
Effect of resveratrol on the progression of experimental periodontitis in an ovariectomized rat model of osteoporosis : Morphometric , immune - enzymatic , and gene expression analysis . - pubmed
OBJECTIVE : This study aimed to determine the role of resveratrol ( RESV ) on the progression of experimental periodontitis ( EP ) in ovariectomy rats ( OVT ) . - pubmed
Thus , this study aimed at investigating the effect of RESV on the progression of EP in estrogen - deficient rats . - pubmed
Advanced head and neck cancer ( HNC ) can invade facial bone and cause bone pain , thus posing a significant challenge to the quality of life of patients presenting with advanced HNC . - pubmed
The present study was designed to investigate HNC bone pain ( HNC - BP ) in an intratibial mouse xenograft model that utilized an HNC cell line ( SAS cells ) . - pubmed
The in vivo efficacy of galeterone as single drug alone and its ability in augmenting chemotherapy 's efficacy were also shown in breast cancer xenograft mouse model . - pubmed
In this article , we present a case with HaNDL syndrome in a 28 - year - old male patient who presented with confusion and agitation after sudden onset of headache , right hemiparesis , and lymphocytosis pleocytosis . - pubmed
Lesions of mice under rotating shift schedules were larger and contained less prostabilizing fibrillar collagen and significantly increased areas of necrosis . - pubmed
Human papilloma virus genotype distribution in women with premalignant or malignant lesions of the uterine cervix . - pubmed
OBJECTIVE : Cervical cancer is caused by persistent infection with high - risk human papillomavirus ( hrHPV ) . - pubmed
This study evaluated the distribution of different types of hrHPV relative to age in cervical cancer and its precursor lesions . - pubmed
Among HPV - positive women , HPV-16 , HPV-18 , and " HPV other " types were found in 33.5 , 4.4 , and 49.4 % , respectively . - pubmed
Among women with cervical cancer , 75.8 % were infected with HPV-16 or had coinfection with HPV-16 and " HPV other " . - pubmed
CONCLUSIONS : HPV-16 is the most common type of hrHPV in HSIL + lesions . - pubmed
Therefore , women age > = 35 with persistent infection with this type of hrHPV need careful surveillance , as they are at high risk of progression to cervical cancer . - pubmed
Oncofetal protein accompanying irradiation - induced small - bowel adenocarcinoma in the rat . - pubmed
A tumor - associated protein was found in tissue derived from an X - irradiation - induced adenocarcinoma in the small bowel of the rat . - pubmed
It shared common antigenic determinants both with a rat fetal protein and a perchloric acid - soluble protein isolated from the serum of the tumor - bearing rat . - pubmed
[ Increased contents of phenylethanolamine , m - octopamine and p - octopamine in the hypothalamus and brain stem of spontanously hypertensive rats ( S.H.R. - pubmed
Phenylethanolamine , p - octopamine and m - octopamine contents were determined in the hypothalamus and the brain stem of spontaneously hypertensive Rats ( S.H.R. - pubmed
Effects of the diazafluoranthen derivative AC-3579 ( NSC-170561 ) , a new experimental antitumour drug , on rat hepatoma . - pubmed
The effects of AC-3579 ( NSC-170561 ) , a new experimental antitumour drug which depresses phospholipid catabolism in liver , were compared in rat aflatoxin - induced hepatoma and in non - neoplastic hepatocytes surrounding the tumour . - pubmed
Effect of lithium upon plaque and gingivitis in the beagle dog . - pubmed
Animal models of cardiac dysrhythmias . - pubmed
After infusion of 51Cr -- labeled isologous platelets into one patient with no hematological disease and into four patients with thrombocytopenia , radioactivity was measured from 1 to 8 days . - pubmed
Normal platelets survival was determined as 7 to 8 days in the first patient , whereas the thrombocytopenic patients showed a reduced survival , between 1 to 2 days . - pubmed
The percentage of maximum recovery of transfused platelets was severely reduced in those patients with thrombocytopenia , ranging from 13 to 18 % , as compared with the normal 50 % found in the first patient . - pubmed
Such observations are used to implement the utility of serial biopsies from the beagle dog prior to and during long - term study of potential hepatic injury . - pubmed
The authors recommend that any infant having a mid - line lumbar cutaneous abnormality , such as a hemangioma , lipoma , hair patch or dimple , be evaluated to rule out tethering of the spinal cord . - pubmed
Dependence and withdraw syndromes related with tobacco are mentioned . - pubmed
All endometriosis patients were treated medically with either Danazol or Buserelin . - pubmed
The possibility of the rabbit as a model for HIV-1 infection is also discussed . - pubmed
The C cats shared fully with BD cats a dramatic impairment in the visually delayed response . - pubmed
This short - term memory deficit was presumably due to a limited practice in visual learning in cage - reared cats . - pubmed
Coliforms were obtained from 36pc and streptococci from 18pc of swabs . - pubmed
It is a known fact that pH in rodent tumors decline significantly upon heating most likely due to breakdown of the tumor blood circulation . - pubmed
against metrazol - induced seizures was studied in rats aged 7 , 12 , 18 and 90 days . - pubmed
The results differed between the various age groups after longer intervals : The protection was longest in 18 - day - old rats -- seizures did not appear even six hours after VPA administration . - pubmed
On the contrary , all 7 - day - old rat pups exhibited seizures two hours after VPA . - pubmed
In this study , urine - isolated microorganisms from urinary tract infections were generally evaluated , and among these microorganisms , 407 E. - pubmed
coli strains have been researched if they are uropathogenic E. - pubmed
In nonfasted obese rats , bromocriptine dramatically reduced both cholesterol ( from 440 to 130 mg / dl ) and triglyceride ( from 1570 to 540 mg / dl ) levels compared with controls . - pubmed
Retained placenta in cattle : the effect of treatment or nontreatment on puerperal diseases and subsequent fertility . - pubmed
In order to examine the effect of treated and untreated retained placenta ( RP ) on fertility and on the occurrence of puerperal and fertility diseases , the records of 248 cows with RP were examined : 199 cows were treated with intrauterine tetracycline or systemic therapeutics , and 49 were left untreated . - pubmed
The fertility of the cows with RP was lower than that of the controls . - pubmed
The untreated cows with RP seemed to be treated more often for endometritis and repeat breeding than either the treated animals or the controls . - pubmed
As patients with undetected volume contraction may be more endangered by cardiovascular complications , the hematocrit should be monitored before and after dialysis , especially in patients with high weight gain and in children . - pubmed
The safety of phenylpropanolamine in patients with stable hypertension . - pubmed
A patient with osteomyelitis of the distal right first metacarpal bone due to Actinomyces israelii following a punch injury during fisticuffs is described . - pubmed
Analysis of the pus in these infections typically reveals sulfur granules ; strict anaerobic conditions must be employed to culture the etiologic agent , A israelii . - pubmed
Plasma concentrations of TBPA were measured by rocket immunoelectrophoresis in 43 normal and 35 hypothyroid dogs . - pubmed
Reference levels for TBPA ranged between 205 and 474 mg / l. Hypothyroid dogs had a mean TBPA level of 315.0 mg / l ( SD : 91.1 mg / l ) . - pubmed
Forty - five mostly elderly patients with serious infections were treated in a prospective , comparative and randomized pharmacokinetic study with amikacin 11.0 or 15.0 mg / kg administered in a single daily dose as an intravenous , short - term infusion or with amikacin 7.5 mg / kg administered twice daily in the same way . - pubmed
[ Syndrome of lipid hyperperoxidation in burn patients and its correction using autotransfusion of UV - irradiated blood ] . - pubmed
Dynamics of lipid peroxidation was studied in blood serum of patients with burns of various severity and degree . - pubmed
High efficiency of the procedure was demonstrated by reduction of the lipid hyperperoxidation syndrome in patients with burns . - pubmed
To assess the feasibility of percutaneous mitral commissurotomy , we undertook dilatation of mitral stenosis in 26 adults . - pubmed
The procedure was unsuccessful in six patients ( hemopericardium in one , and five failures ) . - pubmed
In a patient with severe valvular and subvalvular disease , mitral regurgitation increased from grade I to grade III . - pubmed
Abnormalities of compliance and functional residual capacity were shown in eight young children aged 2 - 8 years with asthma during an acute attack . - pubmed
In reviewing the literature that links migraine with thromboembolic cerebral vascular events , a distinction is made between two stroke events that occur in migraine patients : stroke associated with a migraine attack ( a migrainous stroke ) and stroke unrelated to a migraine attack ( a non - migrainous stroke ) . - pubmed
The two types of upper limb somatosensory evoked potential abnormality observed in nine patients with syringomyelia were reduced amplitude or absent cervical potentials and an abnormal central conduction time . - pubmed
AZT was administered by intravenous drip infusion to 2 cases of puerperal endometritis , 2 cases ( the same patient ) of vaginal wall abscess , 1 case of postoperative lymphocele infection and 1 case of infected ovarian cyst suspected , and it was effective for all of them . - pubmed
Cranial hyperostosis of squirrel monkeys ( Saimiri sciureus ) . - pubmed
Development of broad spectrum of tumors by ethylnitrosourea in mice and the modifying role of age , sex , and strain . - pubmed
[ Caries incidence in children exposed to repeated topical applications of 8 per cent tin fluoride ] . - pubmed
Hyperkinetic episodes in Scottish Terrier dogs . - pubmed
The clinicopathological findings are reported in a child with congenital oculofacial diplegia , paresis of pharyngeal and laryngeal muscles , and concomitant tetraparesis . - pubmed
These findings are important clinically , particularly as they relate to burn patients who often accumulate iodine concentrations sufficient to depress immune responsiveness . - pubmed
A review of the pathologic material from 34 patients having bronchioloalveolar carcinoma has demonstrated two histopathologic types that have a bearing on the prognosis . - pubmed
We applied the method to monitor ( by use of 24 - h urine specimens ) an uncomplicated , normally progressing pregnancy , a patient with metastatic melanoma being treated with cytostatic drugs , and ( in more detail ) the treatment of a patient with high - grade non - Hodgkin lymphoma . - pubmed
Nuclear estrogen binding sites in human endometriosis . - pubmed
Regional energy balance in rat brain after transient forebrain ischemia . - pubmed
In eleven patients with partial gastrectomy and isoperistaltic jejunal interpositions in ulcer disease the concentrations of bile acids and lysolecithin were determined . - pubmed
While with jejunal interpositions of 20 cm and more in length normal amounts of duodenogastric reflux could be observed , in patients with shorter segments the values were still pathological . - pubmed
Auditory and vestibular function was monitored in 30 patients treated with netilmicin for urinary tract infection . - pubmed
Results of highly sensitive vestibular tests in 15 patients including computerized analysis of the nystagmus responses to caloric tests were compared with results obtained from a sample of normal individuals . - pubmed
Thirty patients with portal hypertension underwent as an emergency measure esophageal transection for uncontrolled variceal bleeding . - pubmed
Immediate operative deaths , within one month , occurred in 17 patients . - pubmed
Five patients had a recurrence of varices . - pubmed
Bleeding recurred in three patients . - pubmed
The patients suffering from left ventricular failure show gastritis of varying intensity . - pubmed
Microcirculatory disorders play an important role in the genesis of changes in the mucous membrane of the stomach in patients with heart failure . - pubmed
Olfactory function was estimated in the group of 37 patients with the penetrating war head injury . - pubmed
In 4 ( 10.8 % ) patients mutual anosmia was found . - pubmed
The patients with complicated penetrating head injury were less successful at the level of all olfactive qualities comparing to those without injury complications . - pubmed
By contrast , 12- and 24 - month - old animals experienced statistically significantly lesser high - energy rebound , developing greater necrosis in the ischemic regions . - pubmed
The purpose of this study was to examine the effects of xenon and nitrous oxide in equipotent doses of 0.3 MAC on pain threshold and auditory response time in six healthy male volunteers . - pubmed
METHODS : High resolution magnetic resonance imaging ( MRI ) examinations of four patients with primary lymphoma of bone were reviewed retrospectively , and in each case intramedullary tumors demonstrated " penetrating channels " extending through the cortex . - pubmed
The MRI studies were correlated with the histopathologic assessment of the tumor for each patient . - pubmed
Polymorphonuclear neutrophils ( PMN ) in freshly voided urines from 20 symptomatic bacteriuric patients were examined . - pubmed
PATIENTS : Two hundred inpatients with steady , moderate or severe pain within 72 hours after orthopedic surgery . - pubmed
INTERVENTIONS : Patients received a single oral dose of bromfenac 25 , 50 , or 100 mg , or ibuprofen 200 or 400 mg , when they experienced steady , moderate or severe pain that , in their opinion , required an analgesic . - pubmed
CONCLUSIONS : The relative potency of the analgesic effect of bromfenac to ibuprofen is 11 - 16.7 in patients with pain after orthopedic surgery . - pubmed
[ Transthoracic and transesophageal follow - up in patients with left atrial thrombosis ] . - pubmed
The embolic risk and changes of thrombus location and size were investigated in 29 consecutive patients with echocardiographically proven thrombi in the left atrium . - pubmed
Thus , the embolic rate was 14 % per patient year . - pubmed
All patients received phenprocoumon ( n = 4 ) or aspirin at the time of embolism . - pubmed
Furthermore , in two patients after cardiac thrombectomy left atrial thrombi were seen again although patients were treated with anticoagulants . - pubmed
On the other hand , in 12 patients ( 5 received oral anticoagulation , 2 received aspirin ) thrombi completely resolved . - pubmed
It can be concluded from these data , that the majority of patients receiving anticoagulation profit from this therapy , however , a complete protection against arterial embolism or reoccurrence of thrombi can not be reached . - pubmed
Left atrial spontaneous echo contrast was the only risk factor significantly associated with thromboembolism in patients with left atrial thrombi . - pubmed
The plasma level achieved by oral administration of 10 mg / kg DV-7028 was more than 10(-7 ) M. The hyperreactivity to serotonin in isolated pulmonary artery segments from MCT - treated rats was significantly reduced by DV-7028 ( 10(-7 ) M ) . - pubmed
The present study suggests that serotonin , released from platelets and accumulated in pulmonary capillaries , contributes to the initiation and/or progression of pulmonary hypertension in MCT - treated rats . - pubmed
[ Nutritional therapy in cancer patients ] . - pubmed
One partial ( 7 + months ) and two complete responses ( 36 and 26 + months ) were observed in 9 patients with metastases from cutaneous melanoma . - pubmed
None of 6 patients with metastases from ocular melanoma responded . - pubmed
Irradiated fetal thymus transplantation in a patient with combined immunodeficiency with predominant T cell defect . - pubmed
Male reproductive toxicity study of nitrazepam in rats . - pubmed
CASE : A 34 - year - old woman was to undergo hysterectomy for menorrhagia unresponsive to treatment . - pubmed
CONCLUSION : Vascular malformation have been found in various organs in individuals with hereditary hemorrhagic telangiectasia . - pubmed
Although involvement of the uterus in hereditary hemorrhagic telangiectasia is uncommon , telangiectasia should be considered in any patient with menorrhagia resistant to treatment . - pubmed
After oral administration , the ED50s of DFU - lactol in the carrageenan - induced paw edema and lipopolysaccharide - induced pyresis assays in rats are comparable with the ED50s observed when dosing with DFU . - pubmed
Of 37 Staphylococcus epidermidis strains isolated between 1980 and 1981 , all were susceptible to vancomycin and teicoplanin on both MHA and BHIA . - pubmed
Population analysis was performed with six strains each of Staphylococcus epidermidis and Staphylococcus haemolyticus ( three with vancomycin MIC & gt ; or = 8 micrograms / ml and three with vancomycin MIC & lt ; or = 4 micrograms / ml using BHIA ) . - pubmed
The population curves of the Staphylococcus epidermidis strains showed a homogeneous pattern of susceptibility . - pubmed
Whereas , those for two Staphylococcus haemolyticus strains ( vancomycin MIC = 8 micrograms / ml using BHIA ) showed a typical heterogeneous pattern . - pubmed
In heifers in which mastitis was associated with increased rectal temperature or other systemic signs , the proportion of clinically affected quarters that were infected with Staph . - pubmed
In children with MPGN and nephrotic syndrome and/or impaired renal function , a trial of steroids is warranted ( grade A ) . - pubmed
In adults with MPGN , impaired renal function , and/or nephrotic - range proteinuria , a trial of aspirin ( 325 mg daily ) , dipyridamole ( 75 to 100 mg tid ) , or a combination of the two for 12 months is reasonable ( grade B ) . - pubmed
A 55 years - old woman was admitted to the hospital because fifteen days of malaise , right upper quadrant pain and fever . - pubmed
Acute effects of thirty minutes of light - intensity , intermittent exercise on patients with chronic fatigue syndrome . - pubmed
BACKGROUND AND PURPOSE : Currently , there is no consensus on exercise prescription for patients with chronic fatigue syndrome ( CFS ) . - pubmed
This investigation examined whether light - intensity , intermittent physical activity exacerbated symptoms in patients with CFS immediately following exercise to 7 days following exercise . - pubmed
After in vitro characterization of each virus , human prostate cancer cells infected with these viruses were subcutaneously injected into athymic mouse . - pubmed
Right GPi lesions were not consistently associated with neuropsychological deficit , except in one study that included a significant proportion of demented patients . - pubmed
The proportion of pertussis infections resulting in recognizable symptoms may have increased among vaccinated persons because of a mismatch of the vaccine strain and circulating Bordetella pertussis strains . - pubmed
Ovariectomized cynomolgus monkeys have previously been investigated as a nonhuman primate model of postmenopausal osteoporosis ( Jerome et al . - pubmed
In the present study , Fourier transform infrared microspectroscopy ( FTIRM ) was used to verify that differences in bone mineral quality and quantity in the vertebrae of mature intact ( INT ) and ovariectomized ( ovx ) monkeys were analogous to those seen in osteoporotic and nondiseased human bones . - pubmed
These spectra were compared with those of both trabecular and previously reported osteonal bone obtained from 3 " normal " and 11 postmenopausal osteoporotic human subjects . - pubmed
While variations in the mineral : matrix ratio ( mineral content ) , carbonate : phosphate ratio , and crystallinity are typical for trabecular bone from iliac crests of normal human subjects , the values of these parameters were relatively static for trabecular bone from postmenopausal osteoporotic human subjects . - pubmed
In general , trabecular bone from postmenopausal osteoporotic human subjects exhibited decreased mineral content ( 1.0 + /- 0.5 vs. 2.9 + /- 0.6 ) , increased crystallinity , and increased carbonate : phosphate relative to controls . - pubmed
These data support the hypothesis that ovariectomized adult monkeys are an excellent model for postmenopausal osteoporosis , and can be used for the evaluation of therapeutic modalities . - pubmed
Microsphaeropsis olivacea keratitis and consecutive endophthalmitis . - pubmed
PURPOSE : To report a case of fungal keratitis with consecutive endophthalmitis caused by Microsphaeropsis olivacea . - pubmed
RESULTS : A 51 - year - old man developed fungal keratitis and consecutive endophthalmitis after sustaining a penetrating injury to the right eye . - pubmed
The ability of Staphylococcus aureus to invade mammalian cells may explain its capacity to colonize mucosa and to persist in tissues after bacteraemia . - pubmed
OBJECTIVE : To evaluate the efficacy of inhaled albuterol for treatment of hyperkalemia in premature neonates by conducting a prospective , randomized placebo - controlled and double - blinded clinical trial . - pubmed
Brain circuits involved in emotional learning in antisocial behavior and social phobia in humans . - pubmed
METHODS : Six patients ranging in age from 6 to 37 years with traumatic high - flow priapism underwent superselective embolization with gelatin sponges ( n=3 ) or minicoils ( n=3 ) . - pubmed
In 2 patients , repeated embolization led to a flow reduction in the fistula , which spontaneously occluded a few days later . - pubmed
CONCLUSIONS : Transarterial superselective embolization is an effective and well - tolerated therapy in patients with traumatic priapism . - pubmed
BACKGROUND : The aim of this study was to identify the independent histopathologic prognostic factors for patients with cervical carcinoma treated with radical hysterectomy including paraaortic lymphadenectomy . - pubmed
METHODS : A total of 187 patients with stage IB to IIB cervical carcinomas treated with radical hysterectomy and systematic retroperitoneal lymphadenectomy were retrospectively analyzed . - pubmed
RESULTS : Using multivariate Cox regression analysis , lymph node ( LN ) status ( negative vs. metastasis to pelvic nodes except for common iliac nodes vs. common iliac / paraaortic node metastasis ) , histopathologic parametrial invasion , lymph - vascular space invasion ( LVSI ) , and histology of pure adenocarcinoma were found to be independently related to patients ' poor survival . - pubmed
For patients who had a tumor histologically confined to the uterus and have neither parametrial invasion nor lymph node metastasis , LVSI was the most important prognostic factor , and histologic type , depth of cervical stromal invasion , and tumor size were not related to survival . - pubmed
The survival of patients with a tumor extending to parametrium or pelvic lymph node(s ) was adversely affected by histology of pure adenocarcinoma . - pubmed
When the tumor extended to common iliac or paraaortic nodes , patients ' survival became quite poor irrespective of LVSI or histologic type of pure adenocarcinoma . - pubmed
Patients ' prognosis could be stratified into low risk ( patients with a tumor confined to the uterus not associated with LVSI : n = 80 ) , intermediate risk ( patients with a tumor confined to the uterus associated with positive LVSI , and patients with squamous / adenosquamous carcinoma associated with pelvic lymph node metastasis or parametrial invasion : n = 86 ) , and high risk ( patients with pure adenocarcinoma associated with pelvic lymph node metastasis or parametrial invasion , and patients with common iliac / paraaortic node metastasis : n = 21 ) with an estimated 5 - year survival rate of 100 + /- 0 ( mean + /- SE)% , 85.5 + /- 3.9 % , and 25.1 + /- 9.7 % , respectively . - pubmed
Prognosis for patients with cervical carcinoma may be stratified by combined analysis of these histopathologic prognostic factors . - pubmed
CONCLUSIONS : Three hundred eighty - one patients reported that they were receiving antidepressant therapy for psychiatric and other medical reasons . - pubmed
CLINICAL IMPLICATIONS : Patients receiving antidepressant therapy are at risk of developing xerostomia and orthostatic hypotension , as well as experiencing the adverse effects of interaction with vasoconstrictors . - pubmed
In 1998 we conducted a multicentre study in Spain on the susceptibility of Streptococcus pyogenes isolates to different 14 - , 15 - and 16 - membered macrolides and clindamycin , in which the number of strains examined was proportional to the number of inhabitants in each geographical area . - pubmed
Surgical correction of cor triatriatum dexter in a dog under extracorporeal circulation . - pubmed
A shiba inu dog with marked abdominal distension was diagnosed with cor triatriatum dexter and surgical correction was performed under extracorporeal circulation . - pubmed
Although several methods have been used to treat cor triatriatum dexter in dogs , the authors consider surgical correction under extracorporeal circulation to be a reliable approach . - pubmed
Metabolic studies of a patient with osteoporosis and diabetes mellitus . - pubmed
The demonstration that initiation of cardiovascular protective medications , including lipid - lowering therapy , prior to hospital discharge for atherosclerotic cardiovascular events results in a marked increase in treatment rates , improved long - term patient compliance , and better clinical outcomes has led to the revision of national guidelines to endorse this approach as the standard of care . - pubmed
Recent studies suggest that when the beta - blocker carvedilol is initiated in acute - MI patients with left ventricular dysfunction with or without symptoms of heart failure prior to hospital discharge , it is safe and effective and improves clinical outcomes . - pubmed
OBJECTIVE : Resistance to imatinib mesylate monotherapy is clearly a barrier to successful treatment of chronic myeloid leukemia ( CML ) patients . - pubmed
METHODS : A total of 225 infants ( mean age 30 days ) were diagnosed with uncomplicated VSD : 31 ( 14 % ) subpulmonary VSD , 159 ( 70 % ) perimembranous , and 35 ( 16 % ) muscular . - pubmed
The patients were divided into two groups according to the presence or absence of congestive heart failure ( CHF ) . - pubmed
SC occurred in 107 patients ( 48 % ) ; three ( 10 % ) of 31 with subpulmonary VSD , 75 ( 47 % ) of 159 with perimembranous VSD , and 29 ( 83 % ) of 35 with a muscular VSD . - pubmed
In three SC patients with a subpulmonary VSD , there was no aortic valve prolapse and no aortic regurgitation . - pubmed
SC occurred in 96 % of SC patients with a perimembranous VSD by the age of 6 years , and in 93 % of those with a muscular VSD by the age of 3 years . - pubmed
In patients without CHF , the rate of SC was 72 % ; 23 % in subpulmonary VSD , 74 % in perimembranous , and 85 % in muscular . - pubmed
The best TcpO(2 ) parameters to predict the efficacy of spinal cord stimulation to improve limb salvage in patients with inoperable critical leg ischemia . - pubmed
METHODS : Studies in which inoperable CLI patients were treated with conservative treatment with or without SCS , and in whom various TcpO ( 2 ) measurements were performed before and during treatment were pooled to investigate which TcpO ( 2 ) parameter(s ) were best to detect patients who benefit most from SCS treatment as to limb salvage . - pubmed
Selection using ( a combination of ) TcpO ( 2 ) measurements substantially improves limb salvage of patients treated with SCS for inoperable CLI . - pubmed
Here we demonstrate 2 patients who showed marked hyperglycemia after androgen - deprivation therapy for prostate cancer and the efficacy of the thiazolidinedione pioglitazone on their glycemic control . - pubmed
Case 1 was a 61 - year - old man diagnosed with prostate cancer who had type 2 diabetes mellitus for 7 years . - pubmed
Six months after starting the leuprolide treatment , the patient complained of thirst and weight loss and was diagnosed with diabetes mellitus with a fasting glucose of 19.4 mmol / L and HbA1c of 9.9 % . - pubmed
Insulin resistance after the androgen - deprivation therapy might lead to marked hyperglycemia in these patients . - pubmed
To explore whether the procoagulant activity of vessel wall - bound cells regulates thrombus expansion , we studied in vitro spatial clot growth initiated by cultured human cells of different types in contact pathway - inhibited , non - flowing human plasma . - pubmed
CONCLUSIONS : If health care personnel are exposed to hepatitis A and B virus , the combined vaccination should be preferred to the concomitant one , as this vaccination scheme induced earlier seroprotection against hepatitis B virus infection ( & gt ; or = 10 IU / l and & gt ; or = 100 IU / l ) . - pubmed
A comparison of continuous renal replacement therapy to intermittent dialysis in the management of renal insufficiency in the acutely III surgical patient . - pubmed
Acute renal failure ( ARF ) occurs in 10 per cent to 23 per cent of intensive care unit patients with mortality ranging from 50 per cent to 90 per cent . - pubmed
We hypothesize that renal function and hemodynamic stability in trauma/ surgical critical care patients are better preserved by CRRT than by ID . - pubmed
We performed a retrospective review of trauma / surgical critical care patients requiring renal supportive therapy . - pubmed
CRRT provides better control of azotemia while preserving hemodynamic stability in patients undergoing renal replacement therapy . - pubmed
Data were 4518 observations of somatic cell score ( SCS ) and bacterial infection from both udder halves of 310 goats from 5 herds in Northern Italy . - pubmed
Patients with advanced , incurable non - small cell lung cancer ( NSCLC ) may derive a clinical benefit from first- and second - line chemotherapy , but third - line treatment with available cytotoxic agents is not effective . - pubmed
Erlotinib is the first of this novel class of drug to demonstrate a statistically significant and clinically relevant difference in overall survival , progression free survival and time to disease related symptoms ( cough , pain , shortness of breath ) compared with treatment with best supportive care in patients who have failed standard first- or second - line chemotherapy . - pubmed
OBJECTIVE : Patients with metastatic breast cancer ( MBC ) generally have a poor prognosis . - pubmed
PATIENTS AND METHODS : From September 2000 to September 2001 , informed consent was obtained from 20 heavily pretreated women with MBC . - pubmed
One patient had grade III neutropenia , which was reversible on cessation of treatment . - pubmed
The goal of this study was to verify the prevalence of anxiety and depression in adolescents , and their relationship with signs and symptoms of TMD . - pubmed
This is a five - year retrospective study of 32 histologically diagnosed cases of Kaposi ' s sarcoma ( KS ) who had undergone HIV antibody testing at the Jos University Teaching Hospital : 13 cases ( 40 % ) were HIV - negative . - pubmed
This pattern of KS seen in Nigerian patients shows similarities with other African countries which have been affected by the HIV epidemic . - pubmed
PARTICIPANTS : Eighteen subjects with recurrent ankle inversion sprain . - pubmed
Early experience with venous stenting suggests that it may be a helpful treatment for patients with PTS but more experience and longer follow - up is required to define the subgroups of patients for whom it is most appropriate . - pubmed
CLINICAL PICTURE : A previously well 12 - year - old boy presented with fever , right - sided flank pain and weight loss of 1 - month duration . - pubmed
Patients with maximum RIFLE class R , class I and class F had hospital mortality rates of 8.8 % , 11.4 % and 26.3 % , respectively , compared with 5.5 % for patients without acute kidney injury . - pubmed
Adherence to maintenance therapy is often poor in patients with asthma . - pubmed
In this 12 - week , randomized , double - blind , double - dummy , parallel - group study , 617 patients with mild to moderate persistent asthma ( mean forced expiratory volume in 1s [ FEV1 ] 78.5 % predicted ) who were not optimally controlled on inhaled corticosteroids ( 200 - 500 microg / day ) were randomized to once - daily budesonide / formoterol ( 80/4.5 microg , 2 inhalations in the evening ) , twice - daily budesonide / formoterol ( 80/4.5 microg , 1 inhalation ) , or a corresponding dose of budesonide once - daily ( 200 microg , 1 inhalation in the evening ) . - pubmed
Budesonide / formoterol administered once daily in the evening is a convenient treatment regimen that is as effective in improving asthma control as twice - daily dosing in patients with mild to moderate persistent asthma . - pubmed
OBJECTIVE : The aim of the present study was to uncover proteins differentially expressed in the WAT of overweight / obese subjects and study the role of the identified proteins in adipocyte differentiation . - pubmed
RESULTS : Human visceral adipose tissue of overweight / obese subjects displayed a differential protein expression profile , compared with that of normal - weight controls . - pubmed
Although potentially autoreactive T cells are present even in healthy subjects , most individuals do not develop autoimmune disease . - pubmed
Despite the available effective therapy the majority of individuals with obstructive sleep apnea and cardiovascular disease remains underdiagnosed and untreated . - pubmed
We investigated such effect in Taiwanese type 2 diabetic patients . - pubmed
MATERIALS AND METHODS : This prospective study has been carried out on 33 patients ( 23 males and 10 females ) with lower ureteral stone ( 17 cases in the right ureter and 16 in the left ) located under iscial spine as was indicated in their KUB . - pubmed
All patients underwent ureteroscopy , and accordingly those with submucosal ureteral stones were distinguished . - pubmed
The average distance between the peak of stone and the middle line of sacrum in patients with submucosal ureteral stone was 9.7 mm with an accuracy of 1.4 mm , a confidence interval 95 % and standard deviation of 3.1 mm . - pubmed
The contact lens wearer ( CLW ) group consisted of 22 eyes of 22 patients ( age distribution , 23 - 50 years ) with a history of refractive errors and more than ten - year soft contact lens wear . - pubmed
Thirty - eight eyes of 38 patients ( age distribution , 18 - 52 years ) with refractive errors but no history of contact lens wear were observed as the controls . - pubmed
Effects of antiepileptic drug therapy on vitamin D status and biochemical markers of bone turnover in children with epilepsy . - pubmed
Reports of decreased serum 25 - hydroxyvitamin D ( 25 - OHD ) and altered bone metabolism associated with antiepileptic drug ( AED ) treatment are inconsistent and predominantly restricted to adults . - pubmed
In this cross - sectional observational study , the aim was to evaluate the influence of AED treatment on vitamin D status and markers of bone turnover in children with epilepsy . - pubmed
Atherosclerosis is accelerated in diabetic patients . - pubmed
These results establish the canine as a model for future studies of TDA . - pubmed
Changes in natriuretic peptides following passive containment surgery in heart failure patients with dilated cardiomyopathy . - pubmed
To evaluate the influence on circulating plasma levels of natriuretic peptides following passive containment surgery in heart failure patients with dilated cardiomyopathy , thirteen patients with dilated cardiomyopathy subjected to cardiac surgery received the Acorn Cardiac Support Device . - pubmed
Patients with ischemic cardiomyopathy ( n=7 ) underwent coronary artery bypass surgery receiving 2 - 3 bypass grafts . - pubmed
In the idiopathic cardiomyopathy group ( n=6 ) , mitral valve plasty was performed in five patients while one patients received the Cardiac Support Device only . - pubmed
Evaluation of drug - metabolizing and functional competence of human hepatocytes incubated under hypothermia in different media for clinical infusion . - pubmed
Hepatocyte transplantation has been proposed as a method to support patients with liver insufficiency . - pubmed
CASE PRESENTATION : A 23 - year - old man presented to us with right hip pain of more than 10 years duration . - pubmed
In the MRAUP group , 87 % of the patients ( 26 patients ) had a final VAS for snoring below 3 , while in the RAUP group 63 % of the patients ( 19 patients ) were below 3 on the scale ( P & lt ; 0.05 ) . - pubmed
These mice , engineered with a common genetic profile to human melanoma , provide a system to study melanoma 's cardinal feature of metastasis and for preclinical evaluation of agents designed to prevent or treat metastatic disease . - pubmed
Cannabis consumers should be made aware of their tobacco use while consuming cannabis and the risk of inducing nicotine addiction through cannabis use , despite the perceived disconnect between the two substances . - pubmed
Nitrofurantoin and Nalidixic acid can be considered as the first line antibiotics for prophylaxis and or treatment of patients with recurrent UTI , while Meropenam and Ciprofloxacin can be used empirically in treating patients with complicated UTI . - pubmed
Construction of flocculating yeast strains by genetic approach and utilization of yeast flocculation for ethanol production from various feedstocks were presented . - pubmed
[ Dorsal release of the ankle with transfer of the posterior tibial tendon in patients with paralytic drop foot ] . - pubmed
RESULTS : Six patients ( mean age 52 years ) presented with a neurologic fixed drop foot deformity that had developed more than 8.3 years ago . - pubmed
licheniformis NH1 strain was achieved in the presence of 7.5 g / l chicken feathers and 1 g / l yeast extract . - pubmed
High levels of 15 - oxygenated steroids in circulation of patients with multiple sclerosis : fact or fiction ? - pubmed
The levels were reported to be increased in patients with multiple sclerosis in a progressive phase and the authors suggested that this could be utilized diagnostically . - pubmed
Using combined gas chromatography - mass spectrometry we fail to detect significant plasma levels of 15HC either in healthy controls or in patients with multiple sclerosis ( levels & lt ; 2 ng / ml ) . - pubmed
Recently , a critical role of iNKT cells in the mouse model of asthma and also in asthma patients has been reported , while some contradictory results have also been described . - pubmed
Here , we summarize the experimental results in mouse and human systems , and discuss the current understanding of the role of NKT cells in the pathogenesis of asthma , including a possible mechanism by which iNKT cells are activated in asthma patients . - pubmed
We evaluated and compared the in vivo tissue distribution and imaging properties of 64Cu - X -( Gly - Ser - Gly )- KCCYSL peptide ( X = 1,4,7,10 , tetraazacyclododecane - N , N ' , N '' , N '''- tetracetic acid , [ DOTA ] 1,4,8,11 - tetraazabicyclo [ 6.6.2 ] hexadecane-4,11 - diacetic acid [ CB - TE2A ] , and 1,4,7 - triazacyclononane-1,4,7 - triacetic acid [ NOTA ] chelators ) in a human breast cancer xenograft mouse model using dual modality PET and computed tomography ( CT ) . - pubmed
The synthesized peptides DO3A - GSG - KCCYSL , CB - TE2A - GSG - KCCYSL , and NO2A - GSG - KCCYSL were purified , radiolabeled with 64Cu , and evaluated for human breast cancer cell ( MDA - MB-435 ) binding , 50 % inhibitory concentration , and serum stability . - pubmed
Cutaneous hyalohyphomycosis caused by Paecilomyces lilacinus successfully treated by oral voriconazole and nystatin packing . - pubmed
We describe a woman with liver cirrhosis with hemorrhagic , bullous , ulcerative leg lesions caused by Paecilomyces lilacinus . - pubmed
Human papillomavirus ( HPV ) can infect oral mucosa , causing asymptomatic infection or warty lesions . - pubmed
Several case - control studies have confirmed HPV as an independent risk factor for squamous cell carcinoma . - pubmed
HPV - related cancers seem to have better prognoses and different risk factors than do HPV - negative ones . - pubmed
The increased risk of HPV infection in HIV patients has been associated with impaired immune response to HPV , highly active antiretroviral therapy , aging of the HIV - infected patients , and direct interaction between the 2 viruses . - pubmed
HPV32 seems to be much more prevalent in asymptomatic HPV infections and warts among those infected with HIV than among those in the general population . - pubmed
METHODS : Twenty - five healthy women of reproductive age with no ocular pathology or systemic diseases were recruited . - pubmed
METHODS AND RESULTS : The study material consisted of a total of 219 patients : 31 with usual ductal hyperplasia ( UDH ) , 25 with atypical ductal hyperplasia ( ADH ) , 30 with ductal carcinoma in situ ( DCIS ) and 133 with invasive carcinoma . - pubmed
This isolate was further identified by partial 16S rDNA sequencing and phylogenetic analysis revealed that the strain belonged to Gammaproteobacteria and was closely related to Halomonas bolviensis ( 96 % sequence similarity , 570 bp ) . - pubmed
In cell culture experiments , top - type hydrogels demonstrated excessive suppression of human epidermal carcinoma A431 cell proliferation over 5 days due to the initial high concentration of released PTX . - pubmed
As an extended work , we sought to confirm its efficacy and safety of Ginsenoside - Rd in patients with acute ischaemic stroke . - pubmed
METHODS : We conducted a randomized , double - blind , placebo - controlled trial involving 390 patients with acute ischaemic stroke in a 3:1 ratio to receive a 14 - day intravenous infusion of Ginsenoside - Rd or placebo within 72 h after the onset of stroke . - pubmed
Physiological response of mouse retinal ganglion cells to electrical stimulation : effect of soma size . - pubmed
An epiretinal prosthesis aims to restore functional vision by stimulating electrically the retinal ganglion cells ( RGCs ) in patients affected by photoreceptor degenerative diseases , such as age - related macular degeneration ( AMD ) and retinitis pigmentosa ( RP ) . - pubmed
Genetic diagnosis and cochlear implantation for patients with nonsyndromic hearing loss and enlarged vestibular aqueduct . - pubmed
OBJECTIVE : To review the genotype and cochlear implantation outcome of patients with nonsyndromic hearing loss and enlarged vestibular aqueduct . - pubmed
METHODS : Twenty - one Chinese children with nonsyndromic hearing loss and enlarged vestibular aqueduct underwent genetic examination . - pubmed
Cochlear implantation is a safe and effective treatment in patients with enlarged vestibular aqueduct . - pubmed
Late - onset patients with sporadic amyotrophic lateral sclerosis in Japan have a higher progression rate of ALSFRS - R at the time of diagnosis . - pubmed
This study sought to investigate the clinical features of patients with late - onset ALS compared with those with early - onset ALS using the progression rate ( DeltaFS ) . - pubmed
METHODS : Forty - five patients with sporadic ALS were divided into 2 groups : 23 patients with early - onset of ALS ( < 65 years ; early onset ) and 22 patients with late - onset ALS ( > = 65 years ; late onset ) . - pubmed
Every patient was followed up from the time of initial diagnosis to the primary endpoint ( death or time culminating in death without tracheostomy or ventilation assistance including noninvasive positive pressure ventilation ) or for at least 48 months after initial diagnosis . - pubmed
CONCLUSION : Our finding suggested that patients with late - onset ALS showed more rapid disease progression than those with early - onset ALS using DeltaFS . - pubmed
Here we identify cold shock as a novel trigger of SG assembly in yeast and mammals . - pubmed
BACKGROUND / AIMS : The immunosuppressive drug tacrolimus ( FK506 ) is used clinically to reduce the rejection rate in patients with kidney transplantation ; however , the resultant nephrotoxicity remains a serious problem . - pubmed
Acoustic radiation force impulse ( ARFI ) imaging with Virtual Touch Tissue Quantification in liver disease associated with cystic fibrosis in children . - pubmed
MATERIALS AND METHODS : Virtual Touch Tissue Quantification , an implementation of US ARFI with shear - wave velocity ( SWV ) measurements was used in 75 children with cystic fibrosis ( CF ) and suspected CFLD to quantify hepatic stiffness . - pubmed
RESULTS : Among CF patients , median SWV was significantly higher in patients with clinical , biochemical and US signs of hepatic involvement than in patients without US evidence of liver disease 1.08 m / s [ ( 95 % confidence interval ( CI ) , 1.02 - 1.14 ] . - pubmed
CONCLUSIONS : ARFI is an innovative screening technique able to help identify CFLD in children . - pubmed
To investigate this mechanism , we examined the levels of intracellular reactive oxygen species ( ROS ) and neurotoxicity in rat primary neurons using E22P - Abeta42 , a mutant that induces a turn at positions 22 and 23 , and E22V - Abeta42 , a turn - preventing mutant . - pubmed
Role of gastric bypass in patients with unresectable advanced carcinoma of stomach . - pubmed
Adipose - specific gene deletion in mice is crucial in determining gene function in adipocyte homeostasis and the development of obesity . - pubmed
PATIENTS AND METHODS : We patch tested 480 consecutive patients , visited at the Mekele IDC , exhibiting symptoms of contact dermatitis . - pubmed
In in vitro screening experiments , MIL showed strong antiproliferation activity in several human cancer cell lines , especially in HepG2 cells with an IC50 of 1.51 microM. - pubmed
In HepG2 tumor - bearing mice models , MIL remarkably and dose dependently inhibited tumor growth . - pubmed
We present the case of a patient who presents a harmonic vestibular deficit of the right ear . - pubmed
In this case we detail the importance of taking hematological disorders into consideration in the differential diagnosis of patients with otoneurological symptoms , and we also review the etiopathogenic mechanisms , symptoms , diagnosis , and therapeutic options for chronic myeloid leukemia with sudden hearing loss and vertigo . - pubmed
MATERIAL AND METHODS : Surgical outcome of 36 patients with large cystic VS was retrospectively assessed , and compared with a group of 67 patients with large solid VS . - pubmed
At 1 year after surgery , 75.8 % of the patients with cystic VSs had favorable facial nerve function and 24.2 % had poor function . - pubmed
CONCLUSION : In most cystic VS patients , favorable facial nerve function can be attained by surgical treatment via retrosigmoid approach . - pubmed
Clinically diagnosed patients with PT ( n = 44 ) and ET ( n = 22 ) with rest tremor were included . - pubmed
Rest tremor suppression was found in 39/44 PD patients and in 2/22 patients with ET during the personal assessment . - pubmed
MATERIAL AND METHOD : This was a retrospective study of 85 patients with nasal polyposis who were treated by endoscopic sinus surgery between the years of 2005 and 2010 . - pubmed
RESULTS : When the patients with ( 16.4 % ) and without ( 83.6 % ) bronchial asthma were compared regarding the eosinophil , lymphocyte , neutrophil , macrophage , mast cells and goblet cells/ epithelial cell rate , no statistical significance was found ( p & gt ; 0.05 ) . - pubmed
The neutrophil amount ( 16.53 + - 19.87 ) on the preparations of the patients with metaplasia was higher than the neutrophil amount ( 8.71 + - 23.98 ) on the preparations of the patients without metaplasia ( p=0.001 ) . - pubmed
Attenuated effects of Neu2000 on hypoxia - induced synaptic activities in a rat hippocampus . - pubmed
Patella dislocation is a common injury in children and adolescents and occurs at a rate of 29 to 43 per 100,000 among the 10- to 17 - year - olds . - pubmed
Effects of body - color mutations on vitality : an attempt to establish easy - to - breed see - through medaka strains by outcrossing . " - pubmed
See - through " strains of medaka are unique tools for experiments : their skin is transparent , and their internal organs can be externally monitored throughout life . - pubmed
The patient was an 18 - year - old man who had undergone surgical closure of ventricular septal defect at the age of 2 years . - pubmed
In regenerative medicine and drug screening for the treatment of severe liver diseases , human induced pluripotent stem ( iPS ) cell - derived mature functional hepatocytes are considered to be a potentially good cell source . - pubmed
When these cells were cultured in a suitable extracellular matrix gel , they eventually formed a cholangiocytic cyst - like structure with epithelial polarity , suggesting that human iPS cell - derived hepatic progenitor - like cells have a bipotent differentiation ability . - pubmed
Approximately 50 % of the world 's population is infected with Helicobacter pylori , leading to chronic inflammation , which increases the risk for gastric adenocarcinoma . - pubmed
Infection of MyD88 - deficient ( Myd88 (-/- ) ) mice with Helicobacter resulted in early and rapid advancement to gastric dysplasia as early as 25 weeks postinfection . - pubmed
METHODS : Using a Social Observation Inventory , 10 patients with bvFTD and 10 patients with Alzheimer ' s disease ( AD ) were compared to their caregiver interlocutors on 1 - hour mealtime , in - home videotaped segments . - pubmed
BACKGROUND : Anomia is a common and debilitating symptom for many dementia sufferers , but is particularly marked in patients with the semantic variant of primary progressive aphasia , semantic dementia ( SD ) . - pubmed
Our results reveal the high thermal and light sensitivities of C. - pubmed
BACKGROUND : It is largely accepted that specific immunological parameters in solid malignancies are associated with patient 's prognosis . - pubmed
So far there are no studies analyzing the macrophage polarization in cervical lymph nodes of oscc patients . - pubmed
In the present study we aimed to correlate macrophage polarization in different anatomical lymph node compartments of patients diagnosed with oscc with histopathologic parameters of the primary tumor ( T- , N- , L- , V- , Pn - status , grading ) . - pubmed
Our aim was to expose rats to one month of training ( 70 or 700 g load ) on a custom - designed weight - lifting apparatus for analysis of reactive forces and muscle morphology prior to muscle hypertrophy . - pubmed
METHODS : Twenty - three patients ( 17 men and 6 women , range : 45 - 85 years old , mean age 65 years ) with malignant liver tumors underwent ultrasound - guided percutaneous tumor ablation [ radiofrequency ( n = 14 ) , microwave ( n = 9 ) ] followed by intravenous contrast - enhanced CBCT . - pubmed
Local tumor recurrence and new liver tumors were found 3 mo after initial treatment in one patient ( 4 % ) . - pubmed
The fusion of baseline MDCT and peri - procedural CBCT images was feasible in all patients and showed satisfactory tumor coverage ( at least 5 - mm margin ) . - pubmed
Further , control groups may be contaminated by significant numbers of preclinical AD patients , which also reduces the power of genetic association studies . - pubmed
More Extensive Pelvic Lymph Node Dissection Improves Survival in Patients with Node - positive Prostate Cancer . - pubmed
aureus ATCC 29213 as the reference and quality control strain . - pubmed
A 58 - year - old man was on dialysis for type II diabetes and chronic renal failure . - pubmed
Occurrence of antibodies to Anaplasma phagocytophilum in patients with suspected tick - borne encephalitis . - pubmed
INTRODUCTION AND OBJECTIVES : Human granulocytic anaplasmosis ( HGA ) is an emerging tick - borne infectious disease caused by Anaplasma phagocytophilum . - pubmed
phagocytophilum in blood sera of humans with suspected tick - borne encephalitis . - pubmed
In a separate analysis of all 48 patients initially identified , the MRIs of patients with ( n = 26 ) and without ( n = 22 ) FBDS were compared by 2 neuroradiologists blinded to the clinical details . - pubmed
The patients often presented with renal mass . - pubmed
Variation in relapse frequency and the transmission potential of Plasmodium vivax malaria . - pubmed
Unexpected arterial wall and cellular inflammation in patients with rheumatoid arthritis in remission using biological therapy : a cross - sectional study . - pubmed
BACKGROUND : Increasing numbers of patients ( up to 40 % ) with rheumatoid arthritis ( RA ) achieve remission , yet it remains to be elucidated whether this also normalizes their cardiovascular risk . - pubmed
RESULTS : Overall , arterial wall inflammation was comparable in RA patients ( n = 23 ) in long - term remission and controls ( n = 17 ) . - pubmed
METHODS : In a prospective study , 41 FECD patients who received DSAEK were compared to 40 cataract patients with normal corneas who received cataract surgery ( control group ) . - pubmed
Catquest-9SF effect size was 1.32 ( CI : 1.0 - 1.6 ) in the control group , 1.84 ( CI : 1.4 - 2.3 ) in FECD patients who received phacoemulsification and intra - ocular lens implantation in combination with DSAEK ( n = 26 ) and 1.37 ( CI : 0.6 - 2.1 ) in pseudophakic FECD patients who received DSAEK ( n = 15 ) . - pubmed
CONCLUSIONS : DSAEK surgery leads to considerable improvement in patient - reported outcome in FECD patients . - pubmed
Microscopic studies revealed that , in incompatible interactions , posthaustorial hypersensitivity reaction was the most prevalent but not exclusive plant defense response in Mv Hombar , and fungal growth was mostly arrested during haustorium formation or in the early stages of colony development . - pubmed
Central vein stenosis is a common problem in patients on dialysis . - pubmed
We describe three patients with left innominate vein stenosis who were known case of chronic kidney disease on haemodialysis and had a left brachio - cephalic fistula and presented with unilateral facial and upper limb oedema . - pubmed
STUDY POPULATION : All newly diagnosed patients with multiple myeloma ( MM ) , smoldering MM , solitary plasmacytomas , and plasma cell leukemia in Denmark are registered annually ; ~350 patients . - pubmed
MAIN VARIABLES : The main registered variables at diagnosis are patient demographics , baseline disease characteristics , myeloma - defining events , clinical complications , prognostics , first- and second - line treatments , treatment responses , progression free , and overall survival . - pubmed
DESCRIPTIVE DATA : Up to June 2015 , 2,907 newly diagnosed patients with MM , 485 patients with smoldering MM , 64 patients with plasma cell leukemia , and 191 patients with solitary plasmacytomas were registered . - pubmed
A 20 - year - old man was admitted with acute respiratory failure . - pubmed
The Effectiveness of Intraocular Methotrexate in the Treatment of Posterior Uveitis in Behcet ' s Disease Patients Compared to Retrobulbar Steroids Injection . - pubmed
To evaluate the efficacy of intravitreal methotrexate ( MTX ) compared to retrobulbar triamcinolone acetonide ( TAA ) , in controlling posterior segment involvement and inducing remissions among Behcet ' s disease ( BD ) patients . - pubmed
31 adult BD male patients with a mean disease duration of 5.45 years who presented with bilateral posterior segment involvement were included . - pubmed
No statistical differences were found between both treatment modalities ; however , based on clinical observations , intravitreal MTX may ensure better control of inflammatory reaction and may encourage longer remission as compared to retrobulbar TAA in BD patients . - pubmed
However , a large fraction of nonresponding patients are AR - V7 - negative . - pubmed
DESIGN , SETTING , AND PARTICIPANTS : Peripheral blood was collected from patients with CRPC ( n=30 ) before initiation of a new line of systemic therapy . - pubmed
[ Treatment Strategy and Results of Carotid Endarterectomy in Chronic Renal Failure Patients ] . - pubmed
Few reports have described carotid endarterectomy(CEA)for chronic renal failure patients because of the unacceptable rate of perioperative stroke and other morbidities . - pubmed
RESULTS : Dialysis treatment was initiated due to diabetes in 4 patients and renal sclerosis in 2 patients . - pubmed
In all the patients , heart vascular lesions and arteriosclerosis risk factors were present . - pubmed
MATERIALS AND METHODS : Follow - up data were collected from 722 patients undergoing radical cystectomy for urothelial carcinoma of the bladder ( UCB ) between 2004 and 2014 . - pubmed
All patients with suspected bladder tumors were eligible for study inclusion . - pubmed
CONCLUSIONS : Our results showed that efficacy and safety of the monopolar and bipolar methods seems to be comparable in patients with bladder tumors . - pubmed
biting midges and can cause abortions and congenital malformations in ruminants and milk drop in dairy cattle . - pubmed
BACKGROUND : Palliative systemic therapy is frequently underutilized in patients with advanced non - small - cell lung cancer ( NSCLC ) , for many reasons . - pubmed
PATIENTS AND METHODS : With ethics approval , we analyzed ESAS scores at initial oncology consultation for 461 patients with advanced NSCLC seen at The Ottawa Hospital Cancer Centre from 2009 to 2012 . - pubmed
CONCLUSIONS : Overall , this demonstrates a novel role for the ESAS as a prognostic tool that could complement existing patient assessment models , such as Eastern Cooperative Oncology Group performance status , in the development of optimal treatment plans and estimation of survival , in patients with advanced lung cancer . - pubmed
Currently no treatments exist for preterm infants with diffuse white matter injury ( DWMI ) caused by hypoxia . - pubmed
We demonstrate that hypoxia activates the ISR in primary mouse oligodendrocyte precursor cells ( OPCs ) in vitro and that genetically inhibiting the ISR in differentiating OPCs increases their susceptibility to in vitro hypoxia . - pubmed
We also show that a well - established in vivo mild chronic hypoxia ( MCH ) mouse model and a new severe acute hypoxia ( SAH ) mouse model of DWMI activates the initial step of the ISR . - pubmed
This study was conducted on 30 OLP patients and 30 healthy individuals . - pubmed
Unstimulated saliva flow was significantly lower in OLP patients ( P = 0.0001 ) . - pubmed
Lungs represent the essential part of the mammalian respiratory system , which is reflected in the fact that lung failure still is one of the leading causes of morbidity and mortality worldwide . - pubmed
Using these approaches , here we identify the earliest preclinical AD stage in subjects from the ADNI and BioFINDER cohorts . - pubmed
Therefore , the aim of the present study was to propose a new murine model of BPH / prostatitis induced by intraurethral injection of LPS . - pubmed
Participants weight gain / loss at 24 months was defined as any value that was either above / below the weight value recorded at baseline . - pubmed
Neuropathological lesions in terminally ill transgenic mice were similar to scrapie - infected wt controls , but less severe . - pubmed
In addition , 2 - AP treatment significantly decreased mortality in a mouse model of pulmonary fibrosis . - pubmed
BACKGROUND : Neuraxial anesthesia improves components of the Virchow 's triad ( hypercoagulability , venous stasis , and endothelial injury ) which are key pathogenic contributors to venous thrombosis in surgical patients . - pubmed
We therefore tested the primary hypothesis that neuraxial anesthesia reduces the incidence of 30 - day VTE in adults recovering from orthopedic surgery . - pubmed
CONCLUSIONS : Neuraxial anesthesia appears to provide only weak VTE prophylaxis , but can be offered as an adjuvant to current thromboprophylaxis in high - risk patients . - pubmed
METHODS : In a longitudinally cohort study , 107 formerly preeclamptic women were assessed for traditional risk factors ( insulin resistance , obesity , dyslipidemia , hypertension , and microalbuminuria ) of metabolic syndrome ( World Health Organization criteria ) at two time points : at 3 - 30 months postpartum ( visit 1 ) and 24 - 65 months later ( visit 2 ) . - pubmed
Pooled gene - trap mutagenesis of haploid human HAP1 cells has proven to be a formidable tool for revealing genes involved in the infection process for a suite of human pathogenic viruses . - pubmed
tuberculosis H37Rv strain identified five active druglike compounds which were further profiled against patient - derived M. - pubmed
The compound was shown to possess low toxicity for mice ( LD50 = 900.0 + - 83.96 mg / kg ) and to be similarly efficacious to etambutol , in the mouse model of drug - sensitive tuberculosis , and to neurotoxic cycloserine in mice infected with MDR tuberculosis . - pubmed
These practices are essential in swine production , especially for highly infectious agents such as porcine reproductive and respiratory syndrome virus ( PRRSv ) . - pubmed
bovis infections will be an important component of the strategy employed to eradicate bovine TB from NZ livestock and wildlife . - pubmed
The discovery of endophytic Bt strains opened new perspectives for studies aimed at the control of sap - sucking insects , such as the Asian citrus psyllid Diaphorina citri Kuwayama ( Hemiptera : Liviidae ) , a vector of " Candidatus Liberibacter spp . - pubmed
In this study , translocation of endophytic Bt strains in citrus seedlings inoculated with Bt suspension delivered by soil - drench , and their systemic pathogenicity to D. - pubmed
Serum Thiol - Disulphide Levels in Epileptic Pediatric Patients . - pubmed
OBJECTIVE : The aim of this study was to determine serum levels of thiol and disulfide in epileptic pediatric patients . - pubmed
METHODS : Ninety patients , 54 epilepsy and 36 controls were included in the study . - pubmed
CONCLUSION : We demonstrated a meaningful relationship between oxidative stress markers and epilepsy in pediatric patients . - pubmed
We discuss here another patient diagnosed with primary cutaneous T - cell LBL at our institute . - pubmed
This patient was initially misdiagnosed as having peripheral T - cell lymphoma NOS . - pubmed
We believe that this presentation of T - LBL is underreported , and many patients are likely misdiagnosed as having high - grade cutaneous T - cell lymphomas . - pubmed
Two groups of six Wistar rats anesthetized with ketamine 200 mg / kg body weight were used . - pubmed
The lack of immunocompetent small animal models for hepatitis C virus ( HCV ) has greatly hindered the development of effective vaccines . - pubmed
Using rodent hepacivirus ( RHV ) , a homologue of HCV that shares many characteristics of HCV infection , we report the development and application of a novel RHV/ outbred rat model for HCV vaccine development . - pubmed
Mekong schistosomiasis caused by Schistosoma mekongi is a public health problem that occurs along the border between southern Laos and northern Cambodia . - pubmed
Our results demonstrate that : ( i ) a large fraction of cationic and non - ionic , but not anionic fMWCNT become trapped at the luminal brain endothelial cell membrane ; ( ii ) despite high cell association , fMWCNT uptake by brain endothelial cells is low ( & lt;1.5 % ID ) and does not correlate with BBB translocation , ( iii ) anionic fMWCNT have highest transport levels across an in vitro model of the human BBB compared to non - ionic or cationic nanotubes ; and ( iv ) fMWCNT are not toxic to hippocampal neurons at relevant abluminal concentrations ; however , fMWCNT charge has an effect on carbon nanotube neurotoxicity at higher fMWCNT concentrations . - pubmed
This quantitative combination of microscopy and spectroscopy , with cellular assays , provides a crucial strategy to predict brain penetration efficiency and neurotoxicity of unlabelled MWCNT and other nanoparticle technologies relevant to human health . - pubmed
Taxane - induced peripheral neuropathy and quality of life in breast cancer patients . - pubmed
METHODS : OST measurements were performed in the metacarpophalangeal , proximal intraphalangeal and wrist joints of 168 RA patients and 114 controls . - pubmed
Additionally , the expansion of indications for ALT which included the implementation of ALT for patients with liver cancer and ALT for patients with liver cirrhosis was discussed . - pubmed
Prosthetic rehabilitation plays a crucial role in restoring patients with facial defects to normalcy . - pubmed
This rare case report of a patient with partial lip necrosis describes her functional , mechanically retained prosthetic rehabilitation , which improved phonetics , esthetics , and function without the need of additional retentive features , increasing convenience and ease of use by the patient and at the same time cutting down cost . - pubmed
Zika virus ( ZIKV ) was responsible in 2015 to 2016 for a major epidemic in South America and was associated in some cases with neurological impairments . - pubmed
Our observations suggest a complex interplay between ZIKV and the BBB , which may trigger local inflammation , leukocyte recruitment , and possible cerebral vasculature impairment . - pubmed
IMPORTANCE Zika virus ( ZIKV ) can be associated with neurological impairment in children and adults . - pubmed
These results were also observed in a mouse model of ZIKV infection . - pubmed
In this clinical trial , the effect of Turmacin on knee joint discomfort in healthy adults subjected to strenuous physical activity was evaluated . - pubmed
Giardia intestinalis is a human parasite that causes a diarrheal disease in developing countries . - pubmed
MATERIALS - METHODS : Patients who were admitted with any kind of LUTS and diagnosed with posterior compartment defects were retrospectively analyzed at urogynecology units of 2 different tertiary referral centers . - pubmed
Patients were included in the analysis if they had isolated posterior vaginal compartment defects with no clinically significant anterior and apical compartment defects . - pubmed
The control group consisted of patients with no pelvic organ prolapse ( POP ) . - pubmed
RESULTS : Of the 340 women with posterior POP , 280 were excluded from the analysis due to combined anterior and/or apical POP with posterior POP and stage 4 POP . - pubmed
When we compared the symptoms between the control group and the remaining 60 patients with isolated posterior POP , there was a statistically significant difference in urge , frequency , nocturia , abnormal emptying , vaginal winding , difficult stool passage ( p = 0.031 , p < 0.001 , p < 0.001 , p = 0.022 , p = 0.041 , and p = 0.039 , respectively ) . - pubmed
One hundred three patients with biopsy - proven MM who underwent WBLDCT were retrospectively enrolled . - pubmed
Patients with lesions > 10 mm showed an odds ratio ( OR ) of 29.8 ( 95%CIs 3.8 - 230.5 ) to develop at least one fracture . - pubmed
WBLDCT represents a reliable imaging - based tool for proper management of MM patients , showing that diffuse form or small lytic lesions may deserve a less frequent follow - up . - pubmed
Effect of granulocyte chalone on acute and chronic granulocytic leukaemia in man . - pubmed
This study reports results from the first clinical tests in which 7 patients with myeloid leukaemia ( 5 acute and 2 chronic leukaemias in metamorphosis ) were treated from 4 to 45 days with granulocyte chalone , the tissue - specific endogenous inhibitor of granulopoiesis . - pubmed
Inhibition of leukaemic growth was distinct in 6 of the 7 patients ; in 5 cases the inhibition was followed by acutal regression of the leukaemia , lasting up to several months in the absence of any maintenance therapy , and in one case the treatment led to a complete remission . - pubmed
This study shows that granulocyte chalone is biologically active against myeloid leukaemia in man , but not that the therapeutic value of the impure chalone is superior to modern cytostatic drugs . - pubmed
[ Effectiveness of a Bulgarian vaccine against Marek ' s disease in broilers ] . - pubmed
Nine goats assigned to three groups were given a jugular infusion of [ 14C ] 3MI ( 0.02 to 0.03 g of 3MI / kg of body weight containing 0.5 muCi / kg of body weight ) for 1.5 hours to induce acute pulmonary edema . - pubmed
Goats pretreated with PB had more severe lung lesions than did 3MI controls . - pubmed
We studied the smoking habits of 114 patients with senile disciform degeneration of the macula . - pubmed
We advise all patients with disciform degeneration to stop smoking . - pubmed
The authors report successful surgical treatment of a patient with an anterior communicating artery aneurysm associated with absence of all of the left cervical carotid arteries . - pubmed
Freeze - fracture of capillary endothelium in rat brain . - pubmed
A carotid endarterectomy with removal of the thrombus and intima was performed with satisfactory recovery of the patient . - pubmed
Plasma zinc levels were measured in both healthy and diabetic individuals having an age range of 10 - 93 years . - pubmed
No significant differences in plasma zinc concentrations were found between males and females in either healthy or diabetic individuals . - pubmed
Hypothermia causes adult - like retention deficits of prior learning in infant mice . - pubmed
Nine - day - old S - W mice receiving deep body hypothermia or hyperthermia immediately after escape training were retested 1 or 24 hr later . - pubmed
Hyperthermia had no effect , with the mice demonstrating retention of the escape response at both retest intervals . - pubmed
[ Preliminary results of the use of an antimycotic drug , clotrimazole ( bis - phenyl -( 2 - chlorophenyl )- 1 - imidazoly - methane : BAY b 5097 ) in local administration for therapy of vaginitis caused by Candida albicans and by Trichomonas vaginalis ] . - pubmed
Cardiac microdialysis measurement of extracellular adenine nucleotide breakdown products during regional ischemia and reperfusion in canine heart : protective effect of propranolol against reperfusion injury . - pubmed
Lhermitte 's sign , as part of cisplatin - related neurotoxicity , was observed in four patients , with ovarian or lung cancer , simultaneously with peripheral neuropathy , after a dose of 375 - 700 mg / m2 . - pubmed
Periodontal and restorative treatment in a patient with familial gingival fibromatosis : a case report . - pubmed
No raised levels ( less than 18 unit ( U ) ml-1 ) of the antigen were found in the serum of 220 normal individuals or of patients with germ cell tumours ( n = 6 ) , granulosa theca cell tumour ( n = 1 ) , gastric carcinomas ( n = 10 ) and colo - rectal carcinomas ( n = 8) . - pubmed
The body weight gain , total feed intake , and feed conversion were determined for male and female chickens between 3 and 7 wk of age . - pubmed
Here we report that milk - transmitted MuMTV also delays the development of the acute erythroleukemia induced by Friend leukemia virus ( FLV ) , and retards , or prevents in some cases , the development of long - term lymphomas caused by its helper component . - pubmed
A number of studies have shown that Chlamydia trachomatis bacteria are important pathogens in urogenital tract infections , such as acute urethritis , acute epididymo - orchitis in male patients and pelvic inflammatory disease in female patients . - pubmed
Altogether 38 tarsorraphies were carried out to 19 patients with corneal epithelial defects resistant to conventional therapy . - pubmed
The main operative indications were lagothalmos , dry eyes and inadequate blinking ( 6 patients ) . - pubmed
An epizootic of feline infectious peritonitis in a captive cheetah population during 1982 - 1983 served to focus attention on the susceptibility of the cheetah ( Acinoyx jubatus ) to infectious disease . - pubmed
A 37 - year - old man with such a tumor in his right eyebrow is reported , and the relevant literature is reviewed . - pubmed
In the acute phase of the disease there was : 1 ) a fall in serum triglycerides in patients with bacteremic pneumococcal disease and in patients with no defined aetiology ( p less than 0.01 and less than 0.005 , respectively ) . - pubmed
Diagnosis and successful treatment of diarrhoea in horses caused by immature small strongyles apparently insusceptible to anthelmintics . - pubmed
It is , therefore , concluded that both the histological structures and cell morphology have close relationships with cell kinetics in the human gastric cancers . - pubmed
Tumors from three separate cohorts of patients were studied as follows : population A , 62 primary breast cancers from 1983 ; population B , 72 primary lesions stored from 1976 to 1983 ; and population C , 23 patients with metastases , treated with hormonal therapy . - pubmed
Some physiological responses to anoxia in the great plains toad , Bufo cognatus . - pubmed
Intramuscular methohexital for rapid induction of short duration sleep in the EEG laboratory : a study of forty - four hyperkinetic children . - pubmed
Severe hepatic damage with submassive necrosis induced in rats by an intraperitoneal injection of a single dose of galactosamine hydrochloride was studied . - pubmed
Parathyroid hyperplasia can sometimes be controlled medically , but the only definitive treatment for hyperplasia and parathyroid adenomata is surgery , to the extent indicated , in these often critically ill patients with this multisystem disease . - pubmed
[ Dietary intake and urinary excretion of various mineral substances in patients with hypertension and ischemic heart disease ] . - pubmed
In patients with coronary heart disease , potassium was eliminated in a greater amount and calcium in a less amount as compared with the amounts supplied with the diet . - pubmed
The most demonstrable retention of sodium was recorded in patients with stage III essential hypertension . - pubmed
Fifty - five infants participated in a double - blind study of indomethacin therapy for the closure of patent ductus arteriosus . - pubmed
For those infants who survived and returned for follow - up at approximately 1 year of age , there was no significant difference between the control ( n = 17 ) and indomethacin ( n = 13 ) groups with respect to physical growth , Bayley scores , respiratory infection , abnormal eye ground , neurological defects , and abnormal EEG . - pubmed
The effects of blended Chinese traditional medicines applied for diabetes mellitus were studied on the pattern of action to the glucose tolerance curves in genetically diabetic KK - CAy mice . - pubmed
Localization of a tumor suppressor gene associated with progression of human prostate cancer within a 1.2 Mb region of 8p22 - p21.3 . - pubmed
Human prostate cancers frequently show loss of heterozygosity at loci on the short arm of chromosome 8 . - pubmed
Peripheral neurotoxicity of taxol in patients previously treated with cisplatin . - pubmed
METHODS : Twenty - two patients affected by a relapse of cisplatin - treated ovarian cancer were examined clinically and neurophysiologically to determine the evolution of taxol - induced peripheral somatic and autonomic neurotoxicity and the possible cumulative effect of a combination of taxol and cisplatin . - pubmed
RESULTS : No patients were excluded from the study because of unacceptable toxicities of any kind . - pubmed
The serial examinations demonstrated that taxol induced onset of ( or worsening of preexisting ) neuropathic symptoms and signs in almost all the patients . - pubmed
It appears that a cumulative , but not dose - limiting , neurotoxic effect occurs using taxol in patients previously treated with cisplatin . - pubmed
[ Immunologically mediated thrombocytopenia in Legionella pneumophila pneumonia ] . - pubmed
Leuprolide acetate was used to produce a constant hypoestrogenic environment in a young patient with histologically confirmed adenomyosis . - pubmed
Conservative medical therapy was initiated because of the patient 's complaint of severe dysmenorrhea coupled with her strong desire for uterine conservation . - pubmed
Dystrophic form of inherited epidermolysis bullosa in a dog ( Akita Inu ) . - pubmed
We report a dog with dystrophic epidermolysis bullosa . - pubmed
japonicus Temminck , had a 3 - year - history of ulcers and scars over the pressure areas on the limbs , and dystrophic nails , since the age of 1 year , which corresponds to early adulthood in humans . - pubmed
BACKGROUND : The short- and long - term effects of levodopa ( L - dopa ) , an oral dopaminergic prodrug , were assessed in patients with severe left ventricular dysfunction . - pubmed
The remaining 22 patients with favorable hemodynamic response to L - dopa ( increase in cardiac index , stroke volume index , reduction in total systemic resistance ) were randomized in a nonblinded fashion to the conventional ( 11 patients ) or conventional plus L - dopa ( 11 patients ) treatment groups . - pubmed
The cause of congestive heart failure was primary dilated cardiomyopathy in 11 patients and ischemic heart disease in 9 patients . - pubmed
CONCLUSIONS : The addition of L - dopa to conventional therapy has beneficial short- and long - term effects in patients with severe left ventricular dysfunction . - pubmed
Short - term ( 6 weeks ) treatment of 15 anti - ANT antibody - positive IDC patients with prednisone was of beneficial effect . - pubmed
Some considerations regarding the use of amino acid racemization in human dentine as an indicator of age at death . - pubmed
[ The normal tear fluid and decreased tearing in patients with Sjogren ' s disease and Sjogren ' s syndrome . - pubmed
MATERIAL AND METHODS : An outcome based study was conducted of 51 patients undergoing construction of a vaginal wall sling for genuine stress incontinence or intrinsic sphincteric deficiency . - pubmed
Despite long - term resolution of stress incontinence in 92 % of those with genuine stress incontinence and 75 % with intrinsic sphincter deficiency , postoperative urge incontinence was the single most important factor affecting patient satisfaction ( p = 0.001 ) . - pubmed
Although preoperative leak point pressure correlated with resolution of stress incontinence , no preoperative demographic factors , symptoms or urodynamic parameters could reliably predict postoperative patients satisfaction . - pubmed
Langerhans and other immunocompetent cells in vocal cord epithelial hyperplastic lesions of patients with chronic laryngitis . - pubmed
The aim of the study was to evaluate the intraepithelial and stromal density of Langerhans cells and lymphoid infiltrate in different stages of carcinogenesis in vocal cord biopsies of 24 randomly selected patients with chronic laryngitis . - pubmed
Here we report a method for extracting DNA from dried blood spots on filter paper which is capable of detecting one Plasmodium falciparum and two Plasmodium vivax parasites / microliter of whole blood by nested PCR without compromising the simplicity of specimen collection or DNA extraction . - pubmed
We describe an Italian boy with this disease whose mental retardation was relatively mild and whose renal tubular acidosis had only a distal component . - pubmed
Establishment and preliminary characterization of human malignant mesothelioma cell lines . - pubmed
The paucity of well - characterized in vitro human models and the consequent shortage of experimental pharmacological studies on mesothelioma reduce the success of its clinical management . - pubmed
It is well known that established human cell lines represent a rapid and advantageous system for in vitro studies of several diseases , such as mesothelioma . - pubmed
Thus , the aim of our study was to establish and characterize a panel of selected human malignant mesothelioma cell lines in order to highlight the biology of this tumor and to test the effectiveness of new antiproliferative compounds . - pubmed
During the last year , we collected 10 pleural effusion samples from patients with diagnosed and pharmacologically untreated mesothelioma . - pubmed
This systematic review assesses six experimental studies into the mechanism of placebo analgesia in human subjects suffering from clinical pain or experimentally induced ischaemic arm pain . - pubmed
After the initial assessment of elderly patients suspected of having malabsorption , as discussed in the first of this pair of articles , more specific investigations may be necessary . - pubmed
Acute toxicity and sublethal effects of white phosphorus in mute swans , Cygnus olor . - pubmed
To estimate the toxicity of P4 to swans and compare the toxic effects to those of mallards ( Anas platyrhynchos ) , we dosed 30 juvenile mute swans ( C. - pubmed
Most swans took 1 to 4.5 days to die in contrast to the few hours normally required in mallards and death appeared to be related more to liver dysfunction than to hemolysis . - pubmed
Considering that over 80 % of human malignant tumors derive from epithelial cells , we studied the effect of As2O3 on HPV 16 DNA - immortalized human cervical epithelial cells ( HCE16 / 3 cells ) in vitro . - pubmed
OBJECT : In this study the authors sought to estimate the frequency , seriousness , and delay of rebleeding in a homogeneous series of 20 patients whom they treated between May 1987 and May 1997 for arteriovenous fistulas ( AVFs ) that were revealed by intracranial hemorrhage ( ICH ) . - pubmed
METHODS : Presenting symptoms in the 20 patients ( 17 men and three women , mean age 54 years ) were acute headache in 12 patients ( 60 % ) , acute neurological deficit in eight ( 40 % ) , loss of consciousness in five ( 25 % ) , and generalized seizures in one ( 5 % ) . - pubmed
Results of the clinical examination were normal in five patients and demonstrated a neurological deficit in 12 and coma in three . - pubmed
A diagnosis of AVF was made with the aid of angiographic studies in 19 patients , whereas it was a perioperative discovery in the remaining patient . - pubmed
Seven patients ( 35 % ) presented with acute worsening during this delay due to radiologically proven early rebleeding . - pubmed
Our novel whole - body scintigraphic method for prospective dosimetry was compared with the 5 h urine collection technique in 10 patients with bone metastases . - pubmed
The total administered activity of 153Sm - EDTMP predicted on a 2 Gy bone marrow dose varied between 35 and 63 % of the standard recommended regimen of 37 MBq.kg-1 and pain relief was experienced by eight of the ten patients . - pubmed
Administration of 153Sm - EDTMP according to the supplier 's recommendations would have delivered bone marrow doses of 3.27 - 5.90 Gy in our patients , doses at which myelotoxicity would have been anticipated . - pubmed
Detection of a radiographically occult fracture of the lateral palmar process of the distal phalanx in a horse using computed tomography . - pubmed
A horse with a suspected injury of the distal phalanx was examined using radiography at day two and 19 after the onset of the lameness , with no definite diagnosis . - pubmed
This report emphasizes the value of computed tomography in diagnosing a geometric complicated nonarticular oblique fracture of the palmar process of the pedal bone in a horse . - pubmed
This study showed that recombinant protein antigens can be used for serological tests to detect bovine lentivirus infection in Australia . - pubmed
Acute ischemic stroke in a young woman with the thiamine - responsive megaloblastic anemia syndrome . - pubmed
Enterococcus faecalis induces the synthesis of at least 42 proteins during 24 h of glucose starvation . - pubmed
METHODS : The patients were enrolled at random in the two surgical groups , provided that a radical excision of the tumour , with only two limits : the level of the lesion from the anal verge and the presence of a severe incontinence instrumentally proven . - pubmed
The effectiveness of aerosolized amphotericin B as prophylaxis against aspergillosis in neutropenic patients needs to be evaluated in a large clinical trial . - pubmed
Activated platelets in patients with severe hypertriglyceridemia : effects of triglyceride - lowering therapy . - pubmed
This study was designed to compare the in vivo platelet activation status between patients with severe hypertriglyceridemia and age- and sex - matched control subjects , and to evaluate the effects of triglyceride - lowering therapy . - pubmed
Sixteen patients with primary hypertriglyceridemia were included in a double - blind , placebo - controlled cross - over trial with 400 mg bezafibrate once daily . - pubmed
In conclusion , patients with hypertriglyceridemia have an increased in vivo platelet activation status , which can be improved by bezafibrate therapy . - pubmed
Echovirus 11 may cause life - threatening infections in small infants . - pubmed
Long - term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy . - pubmed
PURPOSE : To determine whether long - term treatment with valproate ( VPA ) and/or lamotrigine ( LTG ) in children with epilepsy is associated with altered growth and/or bone metabolism . - pubmed
A total of 111 female patients with stroke were selected and with questionnaires filled in and blood samples collected . - pubmed
RESULTS : Women using pills had a higher risk developing hemorrhagic than ischaemic stroke ( OR = 3.03 , P & lt ; 0.05 ) , comparing with those never used pills . - pubmed
Prolonged immune deficiency following allogeneic stem cell transplantation : risk factors and complications in adult patients . - pubmed
Treatment of chronic pleural effusion with pleuroperitoneal shunts in dogs : 14 cases ( 1985 - 1999 ) . - pubmed
OBJECTIVE : To describe complications and outcome associated with chronic nonseptic pleural effusion treated with pleuroperitoneal shunts in dogs . - pubmed
PROCEDURE : Medical records at 4 veterinary schools were examined to identify dogs with chronic nonseptic pleural effusion that were treated by use of a pleuroperitoneal shunt between 1985 and 1999 . - pubmed
RESULTS : 10 of 14 dogs had idiopathic chylothorax , and 4 had an identified disease . - pubmed
All but 1 dog with idiopathic chylothorax and 1 dog with chylothorax from a heart base tumor had unsuccessful thoracic duct ligation prior to pump placement . - pubmed
Eight of 11 dogs with long - term follow - up developed complications ; the overall mean survival time and the interval in which dogs remained free of clinical signs of pleural effusion were 27 months ( range , 1 to 108 months ) and 20 months ( range , 0.5 to 108 months ) , respectively . - pubmed
CONCLUSIONS AND CLINICAL RELEVANCE : Pleuroperitoneal shunts can effectively palliate clinical signs associated with intractable pleural effusion in dogs . - pubmed
We are identifying proteins of interest by coring autoantigenic protein spots from two - dimensional ( 2 - D ) gels of rat sperm extracts and microsequencing them by mass spectrometry . - pubmed
DATA ANALYSIS : Because most common diseases including sepsis have been shown to be influenced by inherited differences in our genes , completion of the Human Genome Project and the concomitant publication of the human single nucleotide polymorphism map both contribute to change our approach to medicine . - pubmed
METHODS : In a prospective cross - sectional study , 91 chronic HD patients and 18 anaemic controls with normal renal function were recruited . - pubmed
METHODS : We assessed 297 consecutive patients with clinical stage I NSCLC who underwent surgical resection at Toneyama National Hospital from 1985 to 1998 . - pubmed
These differences were also observed in patients with pathologic stage I or II tumors but not in those with pathologic stage III or IV tumors . - pubmed
METHOD : We chose to study a population with a primary diagnosis of myofascial pain of the jaw muscles or atypical facial pain and excluded patients with disc displacement , acute arthritis and severe arthrosis . - pubmed
Within nine months , 124 consecutive patients with FAM ( n=108 ) or AFP ( n=16 ) were referred to the departments of maxillary surgery , dentistry or neurology of two interdisciplinary academic pain centers . - pubmed
RESULTS : The group of FAM-/AFP - patients according to our inclusion-/exclusion - criteria presenting with a high pain intensity showed more psychosocial withdrawal ( p=0.013 ) , a worse self - rated psychological status ( p=0.033 ) and a trend towards more somatization ( p=0.093 ) than patients with lower pain intensity . - pubmed
Chronic mild stress in rodents has been proposed to model some of the environmental factors that contribute to the induction of depressive disorders in humans . - pubmed
Therefore , the potential contribution of a reduction in body weight to the chronic mild stress - induced alterations in brain reward function was examined in a separate group of food - restricted rats . - pubmed
Quantitative magnetic resonance imaging ( MRI ) studies in patients with schizophrenia have shown reliable deficits in global tissue volume as well as some regionally specific changes , particularly in the temporal and frontal lobes . - pubmed
[ Modification of viscosity of saliva in dogs following disorders of functional conditions of the central nervous system ] . - pubmed
[ Anatomoclinical findings in spontaneous prolonged epilepsy in a Patas monkey ] . - pubmed
[ Effect of antibiotics on experimental tularemia in the mouse ] . - pubmed
[ Spontaneous arterial sclerosis in animals ] . - pubmed
The group consisted of 126 patients ( mean age : 43.1 years ) with the clinical diagnosis of anal fistula . - pubmed
The patient groups were compared pre- and postoperatively by repeated clinical assessments of cerebral excitation according to a modified Objective Pain Discomfort Scale , OPDS . - pubmed
METHODS : IHb of the fundic mucosa was measured in 108 patients with various gastric diseases ( group 1 ) , and values were compared between H. - pubmed
Fifteen patients with H. - pubmed
Of the 10 children aged 6 - 17 years , all ( 100 % ) fulfilled criteria for both post - traumatic stress disorder ( PTSD ) and major depression with suicidal ideation . - pubmed
CONCLUSION : High - risk pregnancies in liver - transplanted women are generally associated with good outcomes , although an increased rate of preterm labor , intrauterine infections , anemia , and cholestasis were observed . - pubmed
Gonadoblastomas in 5 patients with 46,XY gonadal dysgenesis . - pubmed
We describe five patients with 46,XY gonadal dysgenesis who developed gonadoblastomas , dysgerminomas , a mature teratoma , and a testicular intraepithelial neoplasia . - pubmed
Fibrosarcoma in yellow perch , Perca flavescens ( Mitchill ) . - pubmed
We made an attempt to study the cytological changes in the buccal mucosal cells of iron deficiency anemia , patients . - pubmed
Buccal mucosal cells were scraped from 40 iron deficiency anemia patients and were subjected to morphometric analysis . - pubmed
The phage receptor was present in the outer core of strains of many other Y. - pubmed
enterocolitica serotypes , but also in some Yersinia intermedia strains . - pubmed
In subjects experiencing fatigue when they achieved 50 - 75 % of target heart rate ( THR ) , or those who failed to achieve their THR , atropine was administered in doses of 0.5 mg per minute until the test conclusion ( positive test results or target heart rate achieved ) or until a maximum dose of 2 mg was administered . - pubmed
Time course of inhibition and facilitation in patients with schizophrenia . - pubmed
RESULTS : At short RSIs of 500 ms , chronically ill state hospital schizophrenia patients failed to exhibit NP . - pubmed
CONCLUSIONS : These results suggest that schizophrenia patients are better able to inhibit irrelevant stimuli that are immediate , but the sustainment of inhibition across very short time intervals ( 500 ms ) may fade compared to controls . - pubmed
Our findings demonstrate the ability of the cooled CCD camera to sensitively and non - invasively track the location , magnitude and persistence of luciferase gene expression in human prostate cancer mouse models . - pubmed
Identical wounds from 3 - month - old , untreated rats served as controls . - pubmed
Histologic analysis showed a marked delay in several aspects of wound repair in the aged rats in comparison with that noted in the younger animals . - pubmed
However , the levels of mRNA corresponding to these secreted proteins appeared to be reduced in wound tissue from aged rats . - pubmed
CONCLUSION : In the nonoperative management of children with perforated appendicitis , admission CT findings demonstrating disease beyond the right lower quadrant correlate with treatment failure . - pubmed
In the study , the level of measles immunity was measured among 1,405 military conscripts belonging to the first childhood immunization cohorts that were offered two doses of the measles , mumps and rubella vaccine . - pubmed
MATERIALS AND METHODS : Clinical records of all patients with head and neck schwannomas treated at our department from April 1995 to July 2005 were retrospectively reviewed . - pubmed
All facial schwannoma patients suffered postoperative facial palsy with only partial resolution ( mean final House - Brackman grade , 3.25/6 ) . - pubmed
Among non - facial schwannoma patients , postoperative neural deficit occurred in 12 with partial to complete resolution in 7 . - pubmed
Although snakebites are frequently seen in small animal practice in South Africa , boomslang ( Dispholidus typus ) bites are infrequent due to their shy habits . - pubmed
One of the dogs developed severe adverse reactions to the antivenom , including vomiting , dyspnoea and nystagmus , which responded well to intravenous cortisone and symptomatic treatment . - pubmed
Trafficking in human beigns ( THB ) is recognized as a global public health issue as well as a violation of human rights . - pubmed
AIMS : Pathogenicity of Exobasidium vexans , causal agent of blister blight of tea , was studied in 30 commercially cultivated tea varieties by analysing the antigenic patterns of host and pathogen using immunological techniques . - pubmed
An open - label trial of riluzole , a glutamate antagonist , in children with treatment - resistant obsessive - compulsive disorder . - pubmed
Riluzole , a glutamate antagonist , has theoretical support as an alternative pharmacological treatment and has demonstrated possible benefit in some open - label trials in adults with OCD . - pubmed
METHODS : Six subjects , ages 8 - 16 years , were enrolled in a 12 - week open - label trial of riluzole for OCD symptoms that had resisted prior treatments . - pubmed
CONCLUSIONS : Riluzole may be beneficial for treatment - resistant OCD in young subjects and seems well tolerated . - pubmed
This is the first study to demonstrate dose related effects of PAI-039 on increasing thrombus resolution and inferior vena cava blood flow without adverse effects on anti - coagulation in a rat stenosis model of venous thrombosis . - pubmed
Prevalence and identification of fungal DNA in the small intestine of healthy dogs and dogs with chronic enteropathies . - pubmed
The aim of this study was to evaluate the prevalence of fungal DNA in the small intestine of healthy dogs and dogs with chronic enteropathies . - pubmed
These results indicate a high prevalence and diversity of fungal DNA in the small intestine of both healthy dogs and dogs with chronic enteropathies . - pubmed
Of the 153,180 CHF patients , 37.2 % were anemic . - pubmed
After a minimal follow - up of 6 months , 46.8 % of anemic patients died compared with 29.5 % of nonanemic patients . - pubmed
METHODS : A total of 182 patients with facial nerve injury were reviewed . - pubmed
Have changes in systemic treatment improved survival in patients with breast cancer metastatic to the brain ? - pubmed
Newly developed systemic treatment regimens might lead to improved survival also in the subgroup of breast cancer patients that harbour brain metastases . - pubmed
However , such treatment was performed nearly exclusively in those patients with brain metastases that belonged to the prognostically more favourable groups . - pubmed
Nevertheless , the present results are compatible with the hypothesis that improved systemic therapy might contribute to prolonged survival in patients with brain metastases from breast cancer . - pubmed
Here , we analyzed in the blowfly Calliphora vicina the visuomotor transformation from motion - sensitive neurons in the lobula plate [ V2 and vertical system ( VS ) cells ] onto premotor descending neurons [ descending neurons of the ocellar and vertical system ( DNOVS ) cells ] feeding into the motor circuit of the fly thoracic ganglion . - pubmed
Mild hypohydration induced by exercise in the heat attenuates autonomic thermoregulatory responses to the heat , but not thermal pleasantness in humans . - pubmed
Hypohydration caused by exercise in the heat attenuates autonomic thermoregulation such as sweating and skin blood flow in humans . - pubmed
CASE : A 57 - year - old women , underwent 8 years ago laparoscopic cholecystectomy for acute cholecystitis . - pubmed
Co infection with Plasmodium and helminth parasites is associated with significantly ( p & lt ; 0.001 ) higher anaemia prevalence than single infection with Plasmodium parasites . - pubmed
They were selected patients with normal uptake or a single tumor . - pubmed
Further studies are needed to address factors related to the observed effects of soy isoflavones on SBP and to verify the effect in hypertensive patients . - pubmed
Community - associated methicillin - resistant Staphylococcus aureus ( CA - MRSA ) infections are predominantly those affecting skin and soft tissues . - pubmed
Isogenic hla - negative ( Deltahla ) strains caused skin lesions in a mouse infection model that were significantly smaller than those caused by wild - type USA300 and Newman strains . - pubmed
Moreover , infection due to wild - type strains produced dermonecrotic skin lesions , whereas there was little or no dermonecrosis in mice infected with Deltahla strains . - pubmed
CONCLUSION : Acupuncture - moxibustion apparently relieves the symptoms of xerophthalmia , promotes tear secretion and improves the life quality of patients . - pubmed
METHODS : For this study , first - ever ischemic stroke patients who were admitted within 1 month of stroke onset during the period of March 2002 through December 2008 were included . - pubmed
Data on ischemic stroke patients were collected which included : demographics , risk factors , treatment administered , stroke - related complications and 3 - month , 6 - month and 1 - year death and disability . - pubmed
RESULTS : Of the 2,683 patients included in this study , 366 ( 13.6 % ) had AF . - pubmed
In this group , valvular AF was observed in 153 ( 41.8 % ) patients . - pubmed
Compared to patients without AF , patients with AF were older ( 66.1 vs. 63.6 , p = 0.001 ) and had a higher NIHSS score on admission ( median 10 vs. 4 , p & lt ; 0.001 ) and more frequently suffered from hemorrhagic transformation ( 7.3 vs. 2.8 % , p & lt ; 0.001 ) , pulmonary infection ( 27 vs. 10.6 % , p & lt ; 0.001 ) , urinary tract infection ( 8.5 vs. 3.0 % , p & lt ; 0.001 ) , acute gastrointestinal tract hemorrhage ( 4.1 vs. 1.9 % , p = 0.008 ) , electrolyte disturbance ( 5.2 vs. 1.8 % , p & lt ; 0.001 ) , acute renal failure ( 1.1 vs. 0.5 % , p = 0.005 ) and urinary incontinence ( 3.8 vs. 0.6 % , p & lt ; 0.001 ) during hospitalization . - pubmed
The percentages of patients with AF who received oral anticoagulants were 3.3 % before stroke onset and 14.2 % at discharge . - pubmed
Moreover , patients with AF had a higher proportion of disability ( determined as modified Rankin Scale score 3 - 5 ) in 3 - month , 6 - month and 1 - year follow - ups ( 46.6 , 41.9 and 37.6 vs. 29.1 , 24.0 and 19.3 % , respectively , p & lt ; 0.001 ) and higher case fatality in hospitalization , 3 - month , 6 - month and 1 - year follow - ups ( 10.1 , 25.5 , 29.1 and 34.0 vs. 2.0 , 7.4 , 8.8 and 11.6 % , respectively , p & lt ; 0.001 ) . - pubmed
CONCLUSIONS : Ischemic stroke patients with AF have a poorer outcome , a higher frequency of stroke - related complications and a higher case fatality than patients without AF . - pubmed
Oral anticoagulants were underused in AF patients . - pubmed
RESULTS : In cases of incidental meningioma , its location , size and radiological aspect , the patient 's age , the eventual unknown symptoms and the multiplicity of the lesions must all be considered . - pubmed
CONCLUSION : We recommend neurosurgical consultation for all patients with an incidental meningioma . - pubmed
During injection in increments ( limited by patient discomfort ) , the patients were asked continually to quantify their pain experience on a visual analog scale ( VAS ) and on a 0 - 3 verbal categorical rating scale ( VRS ) after 50 , 80 and 100 mL of infusion over a 20 minute period . - pubmed
RESULTS : PDPH occurred in 60 of 1,716 patients undergoing dural puncture ( 3.5 % ) . - pubmed
The technique of repeated caudal saline injections is easy , rapid , and effective in providing the patient with almost immediate headache relief . - pubmed
The activities of total ( 210 ) Pb in caribou and muskox bones were found to be 1 - 2 orders of magnitude higher than that of parent - supported ( 210 ) Pb indicating the potential for dating of bones of terrestrial mammals ( time elapsed since the death of the animal ) based on the excess ( 210 ) Pb method exists . - pubmed
BACKGROUND AND IMPORTANCE : We report the case history of solitary hypoglossal paraganglioma in a 64 - year - old woman . - pubmed
CLINICAL PRESENTATION : A 64 - year - old woman presented with a short history of dysphonia , occasional dysphagia , tinnitus , altered taste , and unilateral left - sided tongue wasting . - pubmed
We report on a surgically resected perineurioma of the falx cerebri in an 86 - year - old woman . - pubmed
Evaluate the early and long term surgical and functional results of the ileal pouch - reservoir ( IPAA ) in patients with intractable ulcerative colitis . - pubmed
Scientific inquiry has provided incredible insight into the complex etiology of weight gain but must be viewed as an interaction between a human 's propensity to conserve calories for survival in a world with an abundance of it . - pubmed
Natural killer cell mediated missing - self recognition can protect mice from primary chronic myeloid leukemia in vivo . - pubmed
A novel bacterial strain , YC7001(T ) , was isolated from the rhizosphere soil of rice collected at Jinju , Korea , and was characterized using a polyphasic approach . - pubmed
Cells of strain YC7001(T ) were Gram - negative - staining , yellow - pigmented , rod - shaped , aerobic , heterotrophic and non - motile . - pubmed
The DNA - DNA relatedness value of strain YC7001(T ) with C. - pubmed
The major fatty acids of strain YC7001(T ) were C(15:0 ) iso , C ( 16:1 ) omega5c and C ( 17:0 ) iso 3 - OH . - pubmed
The type strain is YC7001(T ) ( = KACC 14533(T ) = JCM 16595(T ) ) . - pubmed
Does a nondipping pattern impact the right ventricle in hypertensive patients ? - pubmed
METHODS : This cross - sectional study included 189 recently diagnosed hypertensive patients . - pubmed
RESULTS : The dipping blood pressure pattern was found in 107 ( 57 % ) participants , whereas the nondipping pattern was present in 82 ( 43 % ) hypertensive patients . - pubmed
Nanoparticle - based clodronate delivery mitigates murine experimental colitis . - pubmed
Altered diffusion tensor imaging measurements in aged transgenic Huntington disease rats . - pubmed
Rodent models of Huntington disease ( HD ) are valuable tools for investigating HD pathophysiology and evaluating new therapeutic approaches . - pubmed
The first transgenic rat model for HD exhibits progressive late - onset affective , cognitive , and motor impairments , as well as neuropathological features reflecting observations from HD patients . - pubmed
In this report , we contribute to the anatomical phenotyping of this model by comparing high - resolution ex vivo DTI measurements obtained in aged transgenic HD rats and wild - type controls . - pubmed
These changes are largely compatible with DTI findings in preclinical and clinical HD patients . - pubmed
We confirm earlier reports that HD rats express a moderate neuropathological phenotype , and provide evidence of altered DTI measures in specific HD - related brain regions , in the absence of pronounced morphometric changes . - pubmed
Co - cultivation of the JM/102W strain of Marek ' s disease virus ( MDV ) with reticuloendotheliosis virus ( REV ) resulted in the generation of a recombinant MDV containing the REV long terminal repeat ( LTR ) named the RM1 strain of MDV , a strain that was highly attenuated for oncogenicity but induced severe bursal and thymic atrophy . - pubmed
Susceptible chickens were inoculated intra - abdominally at hatch with the viruses rMd5 - RM1 - LTR , rMd5 BAC parental virus , wild - type strain Md5 , or strain RM1 of MDV . - pubmed
We present 2 patients with persistent dysphagia after repair of esophageal atresia that was caused by EoE. - pubmed
Effect of 1 , 25 ( OH ) 2 vitamin D3 on glucose homeostasis and DNA damage in type 2 diabetic mice . - pubmed
AIMS : The purpose of the study was to examine the effect of 1 , 25 ( OH ) 2 Vitamin D3 supplementation on type 2 diabetic ( T2DM ) mice . - pubmed
MATERIALS AND METHODS : A total of 24 mice were taken and divided into three groups of control ; diabetic and diabetic + vitamin D supplemented ones . - pubmed
OBJECTIVE : To investigate the protective effects of natakalim against rat aortic vascular endothelial cells ( RAVECs ) injuries induced by hypoxia and its mechanisms . - pubmed
HIV , hepatitis C , and most recently Chikengunya virus , and in the case of HIV associated articular manifestations , the introduction of HAART has resulted in a decrease in the incidence and development of newer complications such as the immune reconstitution syndrome . - pubmed
The HPV test has similar sensitivity but more overdiagnosis than the Pap test -- a randomised health services study on cervical cancer screening in Finland . - pubmed
We compared test sensitivity ( in terms of prevented cancers ) and overdiagnosis ( in terms of non - progressive pre - invasive lesions ) between the human papillomavirus test ( HPV test , Hybrid Capture 2 ) and the traditional Pap test in routine screening for cervical cancer . - pubmed
Apoptosis in human hepatoma HepG2 cells induced by corn peptides and its anti - tumor efficacy in H22 tumor bearing mice . - pubmed
This study was aimed at evaluating the anti - tumor mechanism of corn peptides ( CPs ) . - pubmed
Anatomical closure technique of the nasal floor for patients with complete unilateral cleft lip and palate . - pubmed
We describe a new technique for the reconstruction of the nasal floor at the same time as cheiloplasty in patients with complete unilateral cleft lip and palate . - pubmed
Three hundred and fifty - eight patients have been treated using this technique , most of whom ( n = 233 , 65 % ) were boys , and 288 ( 80 % ) presented with a right complete unilateral cleft . - pubmed
The reductions in vertical HIV transmission observed in Europe and North America have helped raise the possibility of the virtual elimination of new pediatric HIV infections and in turn an " AIDS - free generation " . - pubmed
Immunoproteomic characterization of Ambrosia artemisiifolia pollen allergens in canine atopic dermatitis . - pubmed
Canine atopic dermatitis ( CAD ) is an immune system disorder that affects 10 - 15 % of the canine population . - pubmed
Therefore , characterization of Ambrosia artemisiifolia pollen components , in terms of defining major and minor allergens that induce clinically manifested allergic reaction in dogs , is important for valid diagnosis and efficient therapy . - pubmed
This study has , for the first time , characterized and identified major Ambrosia artemisiifolia allergens in CAD , using an immunoproteomic approach . - pubmed
BACKGROUND : The gene encoding c - fos is an important factor in the pathogenesis of joint disease in patients with osteoarthritis . - pubmed
This review focuses on the different features of the metabolic syndrome and the influence of functional foods on these aspects , involving dyslipidemia , improvement of insulin sensitivity , serum lipid profile , antioxidant status , anti - inflammatory status and weight management of humans . - pubmed
With genetic , molecular , imaging and electrophysiological studies being supported by behavioural studies using animal models , there is real hope that we may soon understand the fundamental pathology of autism . - pubmed
The Shank family of proteins has been strongly implicated as a contributing factor in autism in certain individuals and sits at the core of the alleged autistic pathway . - pubmed
Brown adipose tissue thermogenesis contributes to emotional hyperthermia in a resident rat suddenly confronted with an intruder rat . - pubmed
In the present study we compared BAT , core body , and brain temperature , and tail blood flow , simultaneously measured , to determine whether BAT thermogenesis contributes to emotional hyperthermia in a resident Sprague - Dawley rat when an intruder rat , either freely - moving or confined to a small cage , is suddenly introduced into the cage of the resident rat for 30 min . - pubmed
However , an improved understanding of the pathophysiology of neuropathic pain and a growing number of adjuvant medications that are useful for the treatment of neuropathic pain provide renewed hope for clinicians and their patients . - pubmed
We report on an infant boy with CNDI who showed growth failure during treatment with sodium restriction . - pubmed
High - dose - rate brachytherapy for vaginal rhabdomyosarcoma using a personalized mold in a 20 - month old patient . - pubmed
[ Molecular typing and surveillance on Salmonella typhimurium strain in Guangdong province , 2009 - 2011 ] . - pubmed
Clinical experiments examined nasal airway secretions obtained from asthmatic children during naturally occurring rhinovirus - induced exacerbations ( n = 20 ) vs. non - asthmatic uninfected controls ( n = 20 ) . - pubmed
Intrauterine exposure to gestational diabetes mellitus ( GDM ) is linked to development of hypertension , obesity , and type 2 diabetes in children . - pubmed
Increased aortic stiffness predicts future development and progression of peripheral neuropathy in patients with type 2 diabetes : the Rio de Janeiro Type 2 Diabetes Cohort Study . - pubmed
We aimed to evaluate the predictors of the development and progression of DPN in a cohort of high - risk patients with type 2 diabetes . - pubmed
METHODS : In a prospective study , 477 patients with type 2 diabetes were clinically assessed for the presence of DPN at baseline and after a median follow - up of 6.2 years ( range 2 - 10 years ) . - pubmed
RESULTS : At baseline , 135 patients ( 28 % ) had DPN , and during follow - up 97 patients ( 20 % ) had either a new development or a worsening of DPN . - pubmed
Patients who showed a development or progression of DPN were taller and had a longer duration of diabetes , a greater prevalence of other microvascular complications and hypertension , greater aortic stiffness and poorer glycaemic control than patients who did not have new or progressive neuropathy . - pubmed
After adjustments for the baseline prevalence of DPN , the patient 's age and sex , and the time interval between DPN assessments ; an increased aortic stiffness ( cf - PWV & gt;10 m / s ) were predictive of new / progressive DPN ( incidence rate ratio 2.04 , 95 % CI 1.28 , 3.23 ; p = 0.002 ) . - pubmed
Taken together , the results show that lysosomal membrane permeabilization and lysosomal dysfunction are triggered by AGEs , which induce autophagic inactivation in TECs from patients with DN . - pubmed
Efficacy of acupuncture in children with asthma : a systematic review . - pubmed
BACKGROUND : We performed a systematic review of the efficacy of various types of acupuncture in the treatment of asthma in children . - pubmed
However , the results suggest that acupuncture may have a beneficial effect on PEF or PEF variability in children with asthma . - pubmed
The methods were applied to eight microarray gene expression data sets , totaling 1324 patients with two clinical endpoints , overall survival and relapse - free survival . - pubmed
Here we report that an aversive experience in mice , such as foot - shock exposure ( FsE ) , induces LHb neuronal hyperactivity and depression - like symptoms . - pubmed
In this article , the recent available information on W toxicity in plants and plant cells is reviewed , and the knowledge gaps and the most pertinent research directions are outlined . - pubmed
In the endangered Scottish chough ( Pyrrhocorax pyrrhocorax ) population , a lethal blindness syndrome is found to be caused by a deleterious recessive allele . - pubmed
( ) report on a strange , lethal , blindness that regularly affects chicks of an endangered bird population . - pubmed
Concomitant aneurysm detection in an intracranial dolichoectasia mouse model using a MicroFil polymer perfusion technique . - pubmed
OBJECTIVE : To assess the feasibility of using MicroFil polymer perfusion to detect concomitant saccular aneurysms in an intracranial arterial dolichoectasia ( IADE ) model in mice , and to report detailed histomorphometric features of these aneurysms . - pubmed
Fifteen concomitant saccular aneurysms were detected in 8 ( 21 % ) of the 38 surviving mice , including 6 at the posterior communicating artery , 1 along the ACA , 2 along the anterior communicating artery complex , 3 along the ICA , and 3 along the middle cerebral artery . - pubmed
CONCLUSIONS : The proportion of subjects developing saccular aneurysms in addition to IADE in our mouse model is similar to the 15 % of patients with IADE who have concomitant saccular aneurysms . - pubmed
Use of dofetilide in adult patients with atrial arrhythmias and congenital heart disease : A PACES collaborative study . - pubmed
BACKGROUND : Arrhythmia management has become the major treatment challenge in adult patients with congenital heart disease ( ACHD ) . - pubmed
We included patients ( age & gt;=18 years ) with congenital heart disease who had atrial fibrillation ( AF ) or intra - atrial reentrant tachycardia treated with dofetilide . - pubmed
A total of 3 ( 4.7 % ) patients had major inpatient adverse events : torsades de pointes ( n = 1 , 1.5 % ) , ventricular tachycardia ( n = 1 , 1.5 % ) , and corrected QT prolongation requiring discontinuation ( n = 1 , 1.5 % ) . - pubmed
Dofetilide was discontinued in 1 patient because of sinus node dysfunction , and another patient discontinued therapy before discharge because of persistent arrhythmia . - pubmed
OBJECTIVE : To carry out a retrospective study of the clinical features of patients with intrauterine hematoma in the second and third trimesters , and discuss the risk factors for poor pregnancy outcomes . - pubmed
[ Establishment of Human Chronic Lymphocytic Leukemia Model in the BALB / c Nude Mice by Using MEC-1 and HG3 Cell Lines ] . - pubmed
OBJECTIVE : To explore the the optimal condition for establishing immune deficiency mouse(BALB / c ) model with CLL via subcutaneous inoculation of human chronic lymphocytic leukemia ( CLL ) cells at different inoculative locations and different cell concentrations . - pubmed
Meanwhile , the tumor - bearing mice were killed , and the tumors were isolated and cut into slices for histopathological examination . - pubmed
In this study , rats were treated with spermidine , an activator of autophagy , and injected with sodium laurate via the internal carotid artery to stimulate cerebral small vessel disease ( CSVD ) . - pubmed
OBJECTIVES : Our aim was to analyze our experience with orthotopic liver transplant for hepatoblastoma patients . - pubmed
MATERIALS AND METHODS : We performed a single - center retrospective analysis of 6 orthotopic liver transplant cases in children with hepatoblastoma from 2001 to March 2015 . - pubmed
Five patients were free of tumor recurrences at a median follow - up of 29.9 months . - pubmed
This study aimed to determine whether ticagrelor 60 mg twice daily ( bid ) provided potent and consistent platelet inhibition in patients with vs without diabetes in the PEGASUS - TIMI 54 platelet function substudy . - pubmed
Out of 180 patients studied , 58 patients were randomised to and had received at least four weeks of ticagrelor 60 mg bid , with 20 ( 34 % ) having diabetes , 58 patients received ticagrelor 90 mg bid , with 12 ( 21 % ) having diabetes , and 64 patients received placebo , with 18 ( 28 % ) having diabetes . - pubmed
Patients with diabetes did not have an increased incidence of high platelet reactivity in either ticagrelor group . - pubmed
Platelet reactivity was similar in patients with diabetes treated with ticagrelor 60 mg vs 90 mg bid . - pubmed
In conclusion , ticagrelor 60 mg bid is equally effective at reducing platelet reactivity in patients with and without diabetes , yielding a consistently high level of platelet inhibition regardless of diabetes status . - pubmed
In addition , the spheroids generated from different human tumor cells exhibited distinct sensitivities toward drug chemotherapeutic agents and radiation as compared with two - dimensional ( 2D ) cultures that often lack in vivo - like biological insights . - pubmed
Induction of chronic cholestasis without liver cirrhosis - Creation of an animal model . - pubmed
Evaluation of changes to the Rickettsia rickettsii transcriptome during mammalian infection . - pubmed
The lifecycle of Rickettsia rickettsii includes infection of both mammalian and arthropod hosts , with each environment presenting distinct challenges to survival . - pubmed
PATIENT SAMPLE : Thirty - one subjects with WAD and 31 age- and sex - matched controls were recruited from an ongoing randomized controlled trial . - pubmed
Purpose : The purpose of this study was to determine the safety of topical ocular administration of a cross - linked , modified hyaluronic acid ( xCMHA - S ) hydrogel , and its effectiveness in accelerating repair and closure of acute and nonhealing corneal ulcers in companion animals as a veterinary treatment and its utility as a model for therapy in human corneal ulceration . - pubmed
Then , 30 dogs and 30 cats with spontaneous acute corneal ulcers were treated with either xCMHA - S ( 0.75 % ) or a non - cross - linked hyaluronic acid ( HA ) solution ( n = 15 per group for each species ) , three times daily until the ulcer had healed . - pubmed
Finally , 25 dogs with persistent nonhealing corneal ulcers were treated with xCMHA - S ( 0.75 % ) twice daily until the ulcer had healed . - pubmed
Topically applied xCMHA - S significantly accelerated closure of acute corneal stromal ulcers in dogs and cats compared with a non - cross - linked HA solution . - pubmed
Further , topical administration of the xCMHA - S aided in closure of nonhealing corneal stromal ulcers in dogs . - pubmed
This study demonstrates that a cross - linked , modified HA hydrogel provides further benefit by accelerating time to corneal wound closure compared to a non - cross - linked HA solution in companion animals , and therefore may be beneficial in fulfilling an unmet need in humans . - pubmed
The study involved 58 patients with chronic noncalculous cholecystitis ( CNC ) divided into two groups . - pubmed
A 55 - year - old morbidly obese woman [ body mass index ( BMI ) 51.2 ] developed acute type A aortic dissection , and she also presented with significant hypoxemia and hypercapnia . - pubmed
Animals were sacrificed after 8 weeks of treatment by an overdose of sodium pentobarbital ( 160 mg / kg body weight ) . - pubmed
STZ60 animals presented with significantly lower body weights compared to both control and STZ30 groups . - pubmed
A recent study characterized the proteomic alterations induced by Coxsackievirus type B ( CVB ) infection of human islets . - pubmed
Simultaneous Video - EEG - ECG Monitoring to Identify Neurocardiac Dysfunction in Mouse Models of Epilepsy . - pubmed
Electroencephalography ( EEG ) and electrocardiography ( ECG ) are widely used clinical diagnostic tools to monitor for abnormal brain and cardiac rhythms in patients . - pubmed
Video - EEG - ECG monitoring in mouse models of epilepsy or other neurological disease provides a powerful tool to identify dysfunction at the level of the brain , heart , or brain - heart interactions . - pubmed
Subcutaneous Ehrlich Ascites Carcinoma mice model for studying cancer - induced cardiomyopathy . - pubmed
In this study , we establish a suitable model to study breast cancer - induced cardiomyopathy in mice . - pubmed
We used Ehrlich Ascites Carcinoma cells to induce subcutaneous tumor in 129 / SvJ mice and studied its effect on heart function . - pubmed
In Ehrlich Ascites Carcinoma bearing mice , we found significant reduction in left ventricle wall thickness , ejection fraction , and fractional shortening increase in left ventricle internal diameter . - pubmed
We found higher muscle atrophy , degeneration , fibrosis , expression of cell - adhesion molecules and cell death in tumor - bearing mice hearts . - pubmed
We propose that Ehrlich Ascites Carcinoma induced tumor can be used as a model to identify potential therapeutic targets for the treatment of heart failure in patients suffering from cancer - induced cardiomyopathy . - pubmed
METHODS : We conducted a longitudinal prospective study of breast cancer patients on tamoxifen ( n = 410 ) . - pubmed
At each visit , blood samples were collected , and patients completed a standardized hot flash survey ( n = 1144 ) that reflected hot flash severity during the 7 days prior to the visit . - pubmed
Most patients ( 92.2 % ) experienced hot flash symptoms with 51.0 % having low HFSS ( 0 - 4 ) and 7.32 % experiencing HFSS & gt ; 25 . - pubmed
Age was significantly associated with hot flash severity , with patients aged 45 - 59 more likely to have higher HFSS . - pubmed
Human gammaherpesviruses are associated with malignancies in HIV infected individuals ; in macaques used in non - human primate models of HIV infection , gammaherpesvirus infections also occur . - pubmed
We comprehensively examine all three - rhesus macaque gammaherpesviruses -Rhesus rhadinovirus ( RRV ) , Rhesus Lymphocryptovirus ( RLCV ) and Retroperitoneal Fibromatosis Herpesvirus ( RFHV ) in macaques experimentally infected with Simian Immunodeficiency Virus or Simian Human Immunodeficiency Virus ( SIV / SHIV ) in studies spanning 15 years at the AIDS and Cancer Virus Program of the Frederick National Laboratory for Cancer Research . - pubmed
Local regressions showed that longitudinal VL patterns in cases and controls , from SIV infection to necropsy , differed for each gammaherpesvirus : while RFHV VL increased only slightly in all animals , RLCV and RRV VL increased significantly and continued to increase steeply in cases ; in controls , VL flattened . - pubmed
Moreover , the probe shows potent phototoxicity to both Gram - negative bacteria ( Escherichia coli ) and Gram - positive bacteria ( Bacillus subtilis ) . - pubmed
Ertugliflozin for treatment of patients with Type 2 diabetes mellitus . - pubmed
Results : A total of 2 033 eligible patients with complete information were screened from 2 224 type 2 diabetic patients . - pubmed
METHODS : A total of 71 girls with PA and 52 healthy girls , as the control group , were recruited . - pubmed
Similar findings were observed in response to injury in porcine vein grafts and stent models in vivo . - pubmed
Favourable subgroups included patients with lung metastasis [ HROS 0.324 ( 95 % CI 0.146 - 0.717 ) , P = 0.008 ] and disease - free interval of & gt;12 months [ HROS 0.307 ( 95 % CI 0.131 - 0.724 ) , P = 0.004 ] , but no difference was observed for metastatic burden . - pubmed
NETs are an important first - line defense mechanism against bacterial , viral , fungal , and parasitic infections , but they can also play a role in autoimmune diseases . - pubmed
NETs are immunogenic and toxic structures that are recognized by the autoantibodies of patients with antineutrophil cytoplasmic antibodies - associated vasculitis ( AAV ) ( i.e. - pubmed
We report the antenatal managing of a patient in which Goujerot - Sjogren disease was diagnosed after the revealing of an atrioventricular block in her fetus . - pubmed
The present study aimed to determine the factors associated with early recurrence and cancer death for patients with ESCC treated by trimodal therapy . - pubmed
PATIENTS AND METHODS : We evaluated risk factors for recurrence within 6 months , as well as cancer death within 1 year based on data from 141 patients with ESCC who underwent NCRT followed by curative esophagectomy . - pubmed
Postoperative complications , ypT , ypN , poorer tumor differentiation , lymphatic invasion and venous invasion were significant factors in a comparison of patients with and without early cancer death . - pubmed
CONCLUSION : Further reduction of postoperative complications are needed after NCRT for patients with ESCC . - pubmed
Meticulous surveillance and postoperative adjuvant therapy should be considered for patients with risk factors for early recurrence and cancer death . - pubmed
Ninety - seven specimens of tumor tissue and 77 adjacent normal tissues from patients with breast cancer were examined . - pubmed
All patients underwent modified radical mastectomy or local tumor resection without lymph node dissection . - pubmed
Twenty - four chronic stroke patients who underwent resting - state functional MRI and diffusion tensor image were retrospectively included . - pubmed
All patients were classified into two groups ( mild motor impairment : 11 patients and severe motor impairment : 13 patients ) according to their Fugl - Meyer motor assessment score . - pubmed
METHODS : We conducted a cross - sectional study of Michigan - born preterm infants utilizing dried blood spots . - pubmed
This study describes the use of an animal model of postmenopausal osteoporosis to generate a comprehensive dataset on miRNA regulation in bone tissue and peripheral blood during bone loss and specifically anti - resorptive and osteo - anabolic treatment . - pubmed
Antimalarials such as quinolines are crucial to fight against malaria , but malaria control is extremely challenged by the limited pipeline of effective pharmaceuticals against drug - resistant strains of Plasmodium falciparum which are resistant toward almost all currently accessible antimalarials . - pubmed
In recent years , numerous of quinoline hybrids were developed , and their activities against a panel of drug - resistant P falciparum strains were screened . - pubmed
The effect of pilocarpine on dental caries in patients with primary Sjogren ' s syndrome : a database prospective cohort study . - pubmed
Pilocarpine , a salivary stimulant , can improve the amount and flow rate of saliva in patients with pSS . - pubmed
RESULTS : A total of 4973 patients with new - onset pSS were eligible for analysis . - pubmed
CONCLUSION : Pilocarpine may have no protective effect on dental caries , periodontitis , or oral candidiasis in patients with pSS . - pubmed
It is still unclear how these pathological changes correlate with the development of CJD symptoms because few patients survive beyond 2 years after diagnosis . - pubmed
Compared with traditional monolayer cell culture , the three - dimensional tumor spheroid has emerged as an essential in vitro model for cancer research due to the recapitulation of the architecture and physiology of solid human tumors . - pubmed
Patients who had a chylothorax in group A had a significantly shorter postoperative hospital stay , less mean drainage volume per day , and less total drainage than those in group B ( 7.25 + - 0.50 days vs. 11.00 + - 2.81 days , p = 0.003 ; 0.64 + - 0.04 L vs. 0.80 + - 0.09 L , p = 0.003 ; 4.64 + - 0.40 L vs. 8.82 + - 2.84 L ; p = 0.002 ) . - pubmed
Patients with diabetic VH were identified in this retrospective study undertaken at King Khaled Eye Specialist Hospital , Riyadh , Saudi Arabia . - pubmed
In brief , the findings of pyroptosis - dependent cancer progression , new drugs and therapeutic target may lead to a promising , novel therapeutic approach for cancer patients . - pubmed
Streptococcus agalactiae Endocarditis and Melena . - pubmed
Resveratrol improves lipid metabolism in diabetic nephropathy rats . - pubmed
RECENT FINDINGS : In new human and nonhuman primate ( NHP ) vaccine trials as well as studies of natural infection , Fc - mediated effector responses have sometimes been observed to correlate with decreased risk of infection or with better clinical outcomes , suggesting a potential role for these responses in HIV-1 prevention and therapy . - pubmed
A 50 - year - old woman developed gait disturbances and dysarthria since the past 2 years . - pubmed
Dystonia is relatively rare in AxD patients , but this case demonstrated that AxD should be listed in the differential diagnosis of extrapyramidal syndromes with abnormalities of the medulla and spinal cord on MRI . - pubmed
The Fluid and Catheter Treatment Trial ( FACTT ) randomized patients with ARDS to conservative versus liberal fluid management strategies . - pubmed
In a propensity score matched analysis , the difference in the effect of a conservative as compared to liberal fluid management strategy on ventilator free days was 2.23 days ( 95 % CI : -0.97 to 5.43 days ) in diabetic patients , and 2.37 days ( 95 % CI : -0.21 to 4.95 days ) in non - diabetic patients . - pubmed
The difference in the effect of a conservative as compared to liberal fluid management on 60 day mortality was 2 % ( 95 % CI : -11.8 % to 15.8 % ) in diabetic patients , and -7.9 % ( 95 % CI : -21.7 % to 5.9 % ) in non - diabetic patients . - pubmed
The antalgic effects of tiapride by IM route are evaluated in a randomized study on 30 patients with different kinds of neoplasia - related pain . - pubmed
Imbalances of T cell subpopulations in patients with atopic diseases and effect of specific immunotherapy . - pubmed
Immunotherapy of a murine ovarian carcinoma with Corynebacterium parvum and specific heteroantiserum . - pubmed
injection of syngeneic murine ovarian carcinoma ( MOT ) cells . - pubmed
Activation of peritoneal cells to produce lysis of tumor in the presence specific antiserum peaked 3 to 7 days after a single injection of C. - pubmed
Of 15 patients with either atrial fibrillation or both left ventricular hypertrophy and an increased cardiace volume , six had pulmonary pressures elevated above normal values ; none of 14 patients with only one of the two signs ( left ventricular hypertrophy or increased cardiac volume ) had elevated pulmonary pressures . - pubmed
Also , the 34 patients with normal roentgenologic and electrocardiographic findings had normal hemodynamics , irrespective of a history of previous AMI , present angina or dyspnea on exertion . - pubmed
It is concluded that hemodynamic studies by means of a balloon - tipped catheter floating in the pulmonary artery are indicated before major surgery in patients with either atrial fibrillation or both electrocardiographic and roentgenologic signs of left ventricular hypertrophy . - pubmed
[ Effect of AS-4370 on gastric motility in patients with diabetic autonomic neuropathy ] . - pubmed
Delayed gastric emptying in diabetic patients occurs with progress of automatic neuropathy as one late complication . - pubmed
In this study , we evaluated the effect of AS-4370 on gastric motility in diabetic patients with autonomic neuropathy . - pubmed
Eight diabetic patients with autonomic neuropathy ( 3 males and 5 females ) with mean age of 56 years old ( range 29 - 66 ) participated to this study after giving written informed consent . - pubmed
Patients showing skin reaction during mitomycin C vesical instillation should be patch tested to make a decision whether the drug might be continued ( toxic reaction ) or discontinued ( allergic reaction ) . - pubmed
The latter are due either to the HIV itself or to opportunistic infections and malignancies . - pubmed
Between November 1980 and July 1989 , 29 ex vivo reconstructions were performed in 12 women and five men ( mean age : 42 years ) for dysplastic lesions of renal artery branches . - pubmed
Fifteen patients had hypertension , associated with advanced renal failure in one case . - pubmed
Eleven of 15 hypertensive patients completely recovered while four were improved . - pubmed
For fibromuscular dysplasia occurring in young patients whose life expectancy is usually long , this type of surgery provides excellent long - term clinical and anatomical results . - pubmed
Emergence of drug - resistant Mycobacterium tuberculosis in HIV - infected patients . - pubmed
Normalization of pressure - natriuresis by nisoldipine in spontaneously hypertensive rats . - pubmed
This study examined whether the calcium antagonist nisoldipine can shift the relations between sodium excretion , papillary blood flow , renal interstitial pressure , and renal perfusion pressure toward lower pressures in spontaneously hypertensive rats . - pubmed
Mean arterial pressure decreased similarly by 9 % and 12 % in Wistar - Kyoto and spontaneously hypertensive rats after nisoldipine ( 0.5 microgram / kg bolus + 0.017 microgram / kg / min ) . - pubmed
In contrast , urine flow and sodium excretion rose by 121 % and 132 % in spontaneously hypertensive rats , and fractional sodium excretion rose from 1.9 + /- 0.3 to 4.2 + /- 0.4 % . - pubmed
Control sodium excretion , papillary blood flow , and renal interstitial pressure were significantly lower in spontaneously hypertensive rats than in Wistar - Kyoto rats when compared at similar renal perfusion pressures . - pubmed
Sodium excretion , papillary blood flow , and renal interstitial pressure all increased in spontaneously hypertensive rats after nisoldipine , whereas it had no effect on papillary blood flow or renal interstitial pressure in Wistar - Kyoto rats . - pubmed
The relations among sodium excretion , papillary blood flow , renal interstitial pressure , and renal perfusion pressure were shifted toward lower pressures in spontaneously hypertensive rats given nisoldipine and became similar to those seen in Wistar - Kyoto rats . - pubmed
These results indicate that nisoldipine normalizes the relations among sodium excretion , renal interstitial pressure , papillary blood flow , and renal perfusion pressure in spontaneously hypertensive rats perhaps by correcting the defect in renal medullary perfusion associated with resetting of pressure natriuresis in this model of hypertension . - pubmed
Masticatory function was examined in 17 patients with mandibular prognathism before and after bilateral sagittal splitting osteotomy of the mandibular rami . - pubmed
Concerning masticatory efficiency , mean values of absorbance of ATP granules in patients with mandibular prognathism were inferior to those of subjects who possess a normal occlusion , even 12 months after operation . - pubmed
The series comprised a total of 54 patients , 14 of whom complained of mild dizziness or nausea which did not require specific treatment . - pubmed
Adrenergic influences on cardiac function during ventricular fibrillation in isolated rat hearts . - pubmed
Effects of norepinephrine ( NE , 10(-6 ) M ) , epinephrine ( E , 10(-6 ) M ) , and vehicle on coronary blood flow ( CF ) , oxygen consumption , and lactate release were compared in 32 isolated rat hearts during 5 min of ventricular fibrillation ( VF ) . - pubmed
A biochemical study of acute ischemia in rodent skin free flaps with and without prior elevation . - pubmed
Rat epigastric flaps , with or without prior elevation , had 10 or 12 hours of acute ischemia . - pubmed
On sodium - dodecyl - sulphate / polyacrylamide gel electrophoresis these proteins co - migrated with proteins immunoprecipitated using serum from rats inoculated with FBJ - MuSV - transformed cells ( tumour - bearing rat serum ) . - pubmed
In a randomized , double - masked study , 41 patients with primary open - angle glaucoma or ocular hypertension were treated with betaxolol 0.5 % or timolol 0.5 % drops for 26 weeks . - pubmed
Two to three hours after the administration patients became psychotic again . - pubmed
Moreover , the beta - carboline norharman was present in blood obtained during acute psychotic episodes and was not present in blood of nonsymptomatic patients nor in blood of healthy controls . - pubmed
A 54 - year - old nonasthmatic man was found to have allergic granulomatosis and angiitis ( AGA ) ( Churg - Strauss syndrome ) with pulmonary lesions suggestive of diffuse panbronchiolitis ( DPB ) at autopsy . - pubmed
Proposed mechanism of inheritance and expression of the human fragile - X syndrome of mental retardation . - pubmed
A mechanism is proposed for the inheritance and expression of the fragile - X - linked syndrome of mental retardation in humans . - pubmed
Excellent results were obtained in two patients with unilateral inveterate dislocation of the mandible operated upon using this procedure . - pubmed
[ Castor bean poisoning ] . - pubmed
Isolation and characterization of an echovirus , possible " prime " strain of echovirus type 12 . - pubmed
Metabolism and concentration of androgenic steroids in abdominal skin of hirsute women with androgenital syndrome . - pubmed
An in vitro study has been made of the steroid metabolism in the abdominal skin in two hirsute women with adrenogenital syndrome , and the concentrations of the various steroids in the skin tissue have been determined . - pubmed
The extents of steroid accumulation compared to the serum level in the same patient were pathologically high in the case of delta 5 - diol , DHT and DHA - S in the abdominal skin of the two hirsute women with adrenogenital syndrome . - pubmed
This confirmed that a state of hyperandrogenism does exist in the skin of these patients . - pubmed
The absorption of effervescent paracetamol ( 1000 mg ) was investigated in nine female patients during a migraine attack and in the same patients when headache free . - pubmed
A comparison of micropuncture and lithium clearance methods in the assessment of renal tubular function in rats with diabetes insipidus . - pubmed
In the present study , fluid delivery from proximal tubules was estimated simultaneously by micropuncture and lithium clearance techniques in anaesthetized Brattleboro rats with diabetes insipidus , under control conditions and following chronic treatment with hydrochlorothiazide . - pubmed
Pharmacokinetics and metabolism of a new hypnotic , zopiclone ( ZD ) , were studied under the following conditions : ( 1 ) rats and dogs were given oral doses of the molecule , 14C - labeled either on the side chain or on the pyrrolopyrazine nucleus ; ( 2 ) rats , rabbits and dogs were given increasing oral doses of the cold compound ; ( 3 ) human subjects in various physiopathological situations -- young and elderly healthy volunteers , patients with liver or renal impairments , nursing mothers -- were given single or repeated doses , p.o . - pubmed
In human volunteers , plasma half - life of ZD increases with age , while patients with liver or renal impairments show little or no modification of pharmacokinetic parameters . - pubmed
Comments on " Transcapillary water and protein flux in the canine intestine with acute and chronic extrahepatic portal hypertension " . - pubmed
Mycoplasma - virus contacts , budding and scars remaining in the membranes of Acholeplasma laidlawii and its virus . - pubmed
All patients with false - positive results by radionuclide angiography had cardiomyopathies , thus this test has a high specificity for left ventricular dysfunction rather than for CAD alone . - pubmed
Criteria developed from the analysis of the test results in the 45 patients with definite diagnoses were then applied to the evaluation of 26 additional patients with atypical chest pain . - pubmed
Based on this study a new approach for the noninvasive evaluation of patients with suspected coronary artery disease is proposed . - pubmed
A total of 98 patients selected and classified into type IIa and IIb hyperlipoproteinemia according to Fredrickson and Lees ( 1965 ) were pre - treated for 6 months with a commercially available combination product ( containing clofibrate and nicotinic acid ) . - pubmed
Detection of poliovirus antibodies and poliovirus genome in patients with the post - polio syndrome . - pubmed
To investigate the role of poliovirus ( PV ) infection in the development of the post - polio syndrome ( PPS ) , we studied the serum , spinal fluid , peripheral blood lymphocytes , and muscle from 47 patients with PPS . - pubmed
The authors examined 21 outpatients with obsessive - compulsive disorder for five neurological soft signs and abnormalities on two neuropsychological tests before and after 10 to 12 weeks of treatment with serotonin reuptake inhibitors . - pubmed
The thymic lesion of the nude mouse causes a profound block in T cell development . - pubmed
Substantial palliation can be offered to the patient with metastatic carcinoid tumour , but the long - term outlook for these patients remains poor . - pubmed
The patient prognosis for a small bowel sarcoma is largely dependent on the tumour grade . - pubmed
A high index of suspicion to improve tumour detection and better treatments of tumours with the same histology at other anatomic sites should enhance the management and outcome of patients with small intestinal malignancies . - pubmed
Comparison of bacterial culture results in bronchoalveolar lavage and nasal lavage fluid in children with pulmonary infection . - pubmed
It aimed to study the relevance of bacterial culture results from nasal lavage fluid as compared with bronchoalveolar lavage fluid in children with pulmonary infection . - pubmed
Purulent nasal secretions were observed in 9 out of 10 children presenting with acute unilateral pneumonia within 1 - 2 days and who had not been treated with antibiotics ( Group 1 ) , and in 10 out of 15 children who had been ill for about 1 - 3 weeks and had not improved , even though antibiotic therapy had been instituted ( Group 2 ) . - pubmed
Treatment with isoniazid and rifampicin for 9 months is adequate for patients with localized pleuropulmonary disease . - pubmed
Necrosis and apoptosis associated with distinct Ca2 + response patterns in target cells attacked by human natural killer cells . - pubmed
Human NK cells were found to be capable of inducing necrosis ( membrane damage ) or apoptosis ( nuclear damage ) depending on the target cell types . - pubmed
Bone marrow biopsy in 50 AIDS patients : a diagnostic approach . - pubmed
It results that bone marrow morphologic examination in HIV - positive patients plays a distinctive role in ruling out the presence of opportunistic infections or associated neoplasias ( haematologic or not ) and in contributing to clarify the significance of a peripheral pancytopenia . - pubmed
pseudomallei can grow and survive in an acidic environment , we suggest multifactorial mechanisms for the pathogenesis of melioidosis due to B. - pubmed
Genotypic and phenotypic virulence markers of the different categories of diarrheagenic Escherichia coli were investigated in 76 strains of the enteropathogenic E. - pubmed
Although its mutagenicity has not been confirmed in mouse germ cells , urethane ( ethyl carbamate ) gas induces a significant increase of X - linked recessive lethal mutations in the germ cells of Drosophila melanogaster . - pubmed
Seventy - four patients from a prospective randomized trial comparing autologous bone marrow ( ABM ) versus blood stem cell ( BSC ) transplantation after high - dose chemotherapy for intermediate and high grade non - Hodgkin ' s lymphoma ( NHL ) were studied for the presence of residual lymphoma prior to transplantation . - pubmed
The technique can be applied safely and effectively for therapy of common tumors in humans . - pubmed
In the current study five patients were treated by interstitial laser palliation with the Nd : YAG laser using special fiberoptic applicator tips , which distribute laser energy efficiently throughout the tumor volume . - pubmed
Two patients were diagnosed with adenoid cystic carcinoma of the paranasal sinuses , one with a recurrent carcinoma of the tongue and oropharynx , one with a recurrent carcinoma limited to the oropharynx , and one patient with a carcinoma of the epi- and oropharynx . - pubmed
The maximum follow - up without recurrence was 2 years in a patient with an adenoid cystic carcinoma tumor of the paranasal sinuses . - pubmed
OBJECTIVE : To characterise cardiac arrhythmias and cardiac autonomic function in 11 elderly men ( mean ( SD ) age 73.2 ( 2.8 ) years ) with a lifelong history of regular very strenuous , exercise . - pubmed
RESULTS : Nine of 11 athletes had complex ventricular arrhythmias compared with five of 12 controls . - pubmed
This method , using the appropriate rate constant , permits the determination of tumor 10B concentration and is widely suitable for clinical BNCT , because the averaged PET data are enough to use in future patients without individual PET study . - pubmed
After oral administration to rats ( 60 mg / kg ) fourteen compounds significantly inhibited the formation of thrombi in arterioles and venules . - pubmed
Pathological angiogenesis in a murine model of human Wilms ' tumor . - pubmed
METHODS : Human Wilms ' tumors were established in the right kidneys of nude mice . - pubmed
Effect of acute hypoxia and hypoxic acclimation on hemorheological behavior in rats with frostbite . - pubmed
It was found that cold injury in rats acclimated to hypoxia was more serious than that in nonacclimated ones . - pubmed
In order to go further into the cause , blood rheological parameters in rats of frostbite at normoxia ( FN ) , frostbite during acute hypoxia ( FAH ) and frostbite during hypoxia after hypoxic acclimation ( FHAC ) groups were observed before and after freezing . - pubmed
The results suggest that the hemorheological behavior is deteriorated in rats acclimated to hypoxia or subjected to freezing , and worsens in hypoxic acclimation rats after freezing . - pubmed
The changes in hemorheological behavior may be one of the causes that would make the frostbite damage more severe in rats acclimated to hypoxia . - pubmed
In two rat strains that are frequently used in behavioural analysis , i.e. - pubmed
The results indicate that , although different rat strains provide different baseline levels of behaviour for testing lesion- or drug - induced behavioural changes , lesions of the medial prefrontal cortex do not only disrupt sustained attention processes , but also induce a strong impairment in response inhibition in both Wistar and Lister rats . - pubmed
STUDY DESIGN : A patient with myxoid liposarcoma in the lumbar epidural space is reported . - pubmed
METHODS : The authors have treated a female patient with myxoid liposarcoma in lumbar extradural space with marginal resection and posterior instrumentation . - pubmed
These patients had evidence of numerous posterior and peripheral retinal lesions predating or occurring simultaneously with macular involvement . - pubmed
Angiography may be reserved for patients with a proven lesion or rapid neurological deterioration taking into account the possibility of interventional treatment . - pubmed
Underuse of inhaled steroid therapy in elderly patients with asthma . - pubmed
Multifocal cystic lesions induced by N - nitroso - bis ( 2 - hydroxypropyl ) amine in the hamster exocrine pancreas . - pubmed
They were found to consist mainly of cells that closely resembled those of hamster pancreatic adenomas and adenocarcinomas , confirming their status as precursors of these tumors . - pubmed
A 69 - year - old woman who had had lambda - type primary macroglobulinemia ( PMG ) since December 1993 was admitted in October 1997 because of obstructive jaundice due to compression of the common bile duct by a retroperitoneal tumor . - pubmed
Monitoring of atrial signals improves the accuracy in identifying supraventricular tachyarrhythmias to prevent inappropriate therapies in patients with implantable ICDs . - pubmed
Defibrillation was successful with a 20 - J shock in all patients . - pubmed
We report a 60 - year - old right - handed Japanese man who showed an isolated persistent typing impairment without aphasia , agraphia , apraxia or any other neuropsychological deficit . - pubmed
In the present study , we examined the frequency of diagnostic comorbidity in psychiatric outpatients presenting for treatment of nonbipolar major depressive disorder ( MDD ) and patients ' desire for treatment for the comorbid disorders . - pubmed
PATIENTS : Twenty - three postoperative patients with severe sepsis and 26 patients with uneventful postoperative course as well as 24 healthy , age - matched subjects . - pubmed
144 Turkish children with acute lymphoblastic leukemia ( ALL ) and 33 with acute nonlymphoblastic leukemia ( ANLL ) were studied and compared with 185 healthy pediatric controls . - pubmed
The number of each cell subset was compared between patients and controls , as well as between groups of patients stratified according to Breslow thickness of the primary tumor ( & lt ; or = 2 mm vs & gt ; 2 mm ) or to survival after 3 years . - pubmed
Autologous tumor - cell vaccination has no contraindications or side - effects , since the patients own materials ( lymphocytes , tumor cells ) are used . - pubmed
Cancer cells may be obtained from tissue biopsies or biological fluids , or from long - term cultures from the patient who is to be vaccinated . - pubmed
Attempts to induce formation of Rous sarcoma virus in cells of tumour XC . - pubmed
Sildenafil was examined in two guinea pig models of airways disease : guinea pigs exposed to LPS or sensitized guinea pigs with atopy exposed to ovalbumen . - pubmed
Intrinsic regulation of the heart in teleosts is partly driven by central venous pressure , which exerts a modulatory role on stroke volume according to the well - known Frank - Starling mechanism . - pubmed
[ Typhoid meningoencephalitis of the guinea pig from intracranial administration of endotoxin and its histologic characteristics ] . - pubmed
BACKGROUND : Human immunodeficiency virus ( HIV ) research involves ongoing , repetitious sequencing of the HIV genome and the massive accumulation of associated investigational data . - pubmed
A 61 - year old female patient with cutaneous sarcoidosis was treated with fumaric acid esters ( Fumaderm ) . - pubmed
[ Effect of urinary tract infections in children with chronic renal failure on peritoneal dialysis ] . - pubmed
UNLABELLED : Urinary tract infections ( UTI ) in children on dialysis treatment are regarded as indirect contraindication for kidney transplantation . - pubmed
Total number of 57 culture - positive UTI episodes were recorded ( 30 in girls , 27 in boys)--1 - episode/11.1 patient - month . - pubmed
In examined group UTI most frequently were present in children with uncorrected urinary tract malformation ( 1 episode/7.7 patient - month ) and in children on immunosuppressive treatment ( 1 episode/5.7 patient - month ) . - pubmed
In children with cystic kidney disease infections had accidental character . - pubmed
CONCLUSIONS : The most frequent occurring pathogen was bacteria Escherichia coli--13 ( 22.8 % ) and Streptococcus faecalis--13 ( 22.8 % ) infections . - pubmed
Streptococcus faecalis strains revealed only partial sensitivity to nitrofurantoin , vancomycin , teicoplanin . - pubmed
METHODS : Serial samples of the airway aspirates ( AA ) were obtained during mechanical ventilation from 21 preterm infants with RDS , of which 12 were survivors ( birth weight 1.48 + /- 0.32 kg and gestational age 31 + /- 1.5 weeks ) and 9 nonsurvivors ( 1.34 + /- 0.31 kg and 30 + /- 2 weeks ) . - pubmed
Urinary calculi form from urate ( salts of uric acid ) and can cause urethral obstruction in male Dalmatians . - pubmed
We postulated that calculi formation might have a genetic component that segregates within the breed , causing some animals to form calculi and others to never form calculi despite excreting uric acid in their urine . - pubmed
We used a survey to ascertain the urinary calculi status based on clinical signs of adult Dalmatians aged 6 years or older , and we used pedigrees from these same animals to estimate the heritability of the clinical manifestation of urate calculi within the breed to be .87 ( .75-.96 ) . - pubmed
PATIENTS AND METHODS : A total of 22 male patients with a mean age of 52.9 years ( range 37 - 67 years ) were treated with SWL for distal ureteral calculi close to the ureteral orifice . - pubmed
None of the patients had urinary tract infection or any abnormal finding on digital rectal examination . - pubmed
At 1 year , all patients completed a questionnaire concerning recent diagnosis of prostate cancer . - pubmed
None of the patients reported prostate cancer at 1 year . - pubmed
Pathologic quiz case : giant mediastinal mass in a 69 - year - old man . - pubmed
A clear understanding of the different aspects of the procedure , including the risks and benefits of the treatment , assists neuroscience nurses in communicating with the PD patient , and providing the most appropriate , knowledge - based pre- and postoperative care . - pubmed
Survey of zona pellucida antigens for immunocontraception of cats . - pubmed
[ Effects of panax notoginseng saponins on the process of renal interstitial fibrosis after unilateral ureteral obstruction in rats ] . - pubmed
OBJECTIVE : To evaluate the effects of panax notoginseng saponins ( PNS ) on the process of renal interstitial fibrosis after unilateral ureteral obstruction in rats . - pubmed
The unilateral ureters of the rats were ligated as the operation to create renal interstitium fibrosis . - pubmed
RESULTS : After operation , the operated rats showed progressive renal interstitium fibrosis . - pubmed
CONCLUSION : The lesions of tubules - interstitium got worse and the renal interstitium showed progressive fibrosis gradually in rats with unilateral ureteral obstruction . - pubmed
We report the case of a 31 - year - old man who was diagnosed with dermatomyositis . - pubmed
Physical examination revealed an induration ( 2 cm x 2 cm ) in the left testis and the patient was diagnosed with stage IIIB left testicular cancer . - pubmed
This case illustrates the importance of palpation of the testes in young patients with dermatomyositis . - pubmed
RATIONALE : Nearly 100 years have passed since the first surgical attempt to remove a craniopharyngioma was undertaken , and the management of patients with these tumors continues to both challenge and frustrate those involved with their treatment . - pubmed
CONCLUSION : The application of radiotherapeutic techniques to the management of craniopharyngioma would begin to complement the role of surgery , but debate would soon emerge as to what constituted the most appropriate management for craniopharyngioma in children . - pubmed
BACKGROUND : Previous studies have drawn attention to the high postoperative mortality and poor survival of patients who present as an emergency with colon cancer . - pubmed
METHODS : The study included 2068 patients who presented with colon cancer between 1991 and 1994 in Scotland . - pubmed
RESULTS : Thirty - day postoperative mortality following potentially curative resection was consistently higher in patients who presented with evidence of blood loss , obstruction or perforation ( all P & lt ; 0.005 ) than in elective patients . - pubmed
The corresponding adjusted hazard ratios ( 95 per cent confidence interval ) for cancer - specific survival , relative to elective patients , were 1.62 ( 1.22 to 2.15 ) , 2.22 ( 1.78 to 2.75 ) and 2.93 ( 1.82 to 4.70 ) for patients presenting with evidence of blood loss , obstruction or perforation ( all P & lt ; 0.001 ) . - pubmed
Treatment of cytomegalovirus retinitis in AIDS patients with intravitreal ganciclovir . - pubmed
BACKGROUND : Cytomegalovirus ( CMV ) retinitis is the most common opportunistic ocular infection in AIDS patients , and frequently leads to blindness if untreated . - pubmed
MATERIAL AND METHOD : The participants were 363 consecutive patients with CMV retinitis treated at the CMV Retinitis Clinic , Maharaj Nakorn Chiang Mai Hospital over the period from June 2001 to December 2003 . - pubmed
CONCLUSION : Intravitreal ganciclovir appeared to be a worthwhile therapeutic alternative for CMV retinitis patients with unaffordable or intolerant to systemic anti - CMV therapy , but the complications of intravitreal injections should also be recognized . - pubmed
Critical time window for intra - arrest cooling with cold saline flush in a dog model of cardiopulmonary resuscitation . - pubmed
BACKGROUND : Mild hypothermia improves outcome when induced after cardiac arrest in humans . - pubmed
Recent studies in both dogs and mice suggest that induction of mild hypothermia during cardiopulmonary resuscitation ( CPR ) greatly enhances its efficacy . - pubmed
METHODS AND RESULTS : Seventeen dogs had ventricular fibrillation cardiac arrest no flow of 3 minutes , followed by 7 minutes of CPR basic life support and 50 minutes of advanced life support . - pubmed
In the early hypothermia group , 7 of 9 dogs survived to 96 hours , 5 with good neurological outcome . - pubmed
In contrast , 7 of 8 dogs in the delayed hypothermia group died within 37 hours with multiple organ failure ( P=0.012 ) . - pubmed
Surgical treatment of overgrowth of the greater trochanter in children and adolescents . - pubmed
Forty - four patients with trochanter overgrowth ( 47 hips ) ages 6 to 17 years underwent surgery . - pubmed
OBJECTIVE : To identify Actinobacillus spp isolates recovered from fetuses and pericardial fluid from horses affected with mare reproductive loss syndrome ( MRLS ) and determine whether these bacterial species are the same as those isolated from clinically normal horses . - pubmed
Of the 18 isolates from horses with pericarditis , 4 were A equuli subsp equuli , 13 were A equuli subsp haemolyticus , and 1 was Bisgaard taxon 10 - like bacterium . - pubmed
CONCLUSIONS AND CLINICAL RELEVANCE : Actinobacillus spp isolates recovered from fetuses and pericardial fluid samples of horses affected by MRLS in 2001 to 2003 were identical to Actinobacillus spp found in the oral cavity and alimentary tracts of healthy horses . - pubmed
One week of weathering increased the accumulation of oxyradicals to almost 2 - fold and triggered the deteriorative cascade , by enhancing the lipid peroxidation and membrane perturbation , leading to cell death in seed tissues and poor germinability and vigour of soybean seeds . - pubmed
Results of one - year anticoagulation in patients with newly detected chronic thromboembolic pulmonary hypertension not treated with pulmonary endarterectomy . - pubmed
INTRODUCTION : Currently pulmonary endarterectomy is considered the method of choice in patients with chronic thromboembolic pulmonary hypertension ( CTEPH ) . - pubmed
There is also doubt about selection of adequate time to refer patients with CTEPH for surgery . - pubmed
METHODS : The prospective analysis involved 29 patients ( 9 male , 20 female ) aged 37 to 82 years , with pulmonary arterial systolic pressure ranging from 39 to 133 mmHg and newly diagnosed CTEPH who had not been treated with pulmonary endarterectomy and were not receiving anticoagulation . - pubmed
CONCLUSIONS : The results of this study suggest that favourable effects of isolated anticoagulation are likely in patients with newly detected CTEPH , mild and moderate baseline pulmonary hypertension and acceptable exercise tolerance . - pubmed
Prediction of remission as a combination of symptomatic and functional remission and adequate subjective well - being in 2960 patients with schizophrenia . - pubmed
Complete remission required that patients achieved symptomatic remission mirroring the Remission in Schizophrenia Working Group criteria , functional remission , and a level of adequate subjective well - being over at least 6 months . - pubmed
CONCLUSIONS : Despite advances in pharmacologic and psychosocial treatments in schizophrenia , close to 90 % of the patients in this study did not fulfill the combined remission criteria . - pubmed
The finding that the course of the disorder depends on early outcome not only in previously untreated but also in more chronically ill patients points toward a critical " window of opportunity " in the course of treatment . - pubmed
OBJECTIVES : To determine the incidence of ventilator - associated pneumonia ( VAP ) among intensive care unit ( ICU ) patients in Japan and to assess the impact of VAP on patient outcomes , including mortality , length of stay , and duration of mechanical ventilation . - pubmed
The standardized mortality rates for the patients with VAP was 1.3 ( 95 % confidence interval [ CI ] , 1.1 - 1.6 ): 1.1 ( 95 % CI , 0.9 - 1.4 ) for the cases due to drug - susceptible pathogens and 1.5 ( 95 % CI , 1.1 - 1.9 ) for the cases due to drug - resistant pathogens . - pubmed
The potential impact of VAP on patient outcomes emphasizes the importance of preventive measures against VAP , especially for VAP caused by drug - resistant pathogens . - pubmed
METHODS : Ten patients with RVT were analyzed retrospectively . - pubmed
RESULTS : Ten kidneys in nine patients were confirmed to have thrombus within the main renal veins , and one patient was confirmed to have thrombus within the small intrarenal veins . - pubmed
MATERIALS AND METHODS : We isolated stromal cells from human squamous cell carcinoma tissue and studied their effect on phenotypic characteristics of normal human interfollicular keratinocytes in vitro . - pubmed
CONCLUSION : The association between caffeine intake and risk of PD was similarly observed in both fast and slow caffeine metabolizers , supporting experimental evidence in animal models that both caffeine and its major metabolite , paraxanthine , are neuroprotective . - pubmed
This double - blind controlled trial included 58 patients with chronic traumatic ulcers . - pubmed
METHODS AND MATERIALS : We analyzed patients treated at the University of Texas Medical Branch between May 2002 and February 2006 who met the following criteria : ( 1 ) definitive IMRT without chemotherapy for oropharyngeal SCC ; ( 2 ) no pretreatment radical surgery ; ( 3 ) minimal follow - up of 1 year . - pubmed
A 90 - day toxicity study of L - asparagine , a food additive , in F344 rats . - pubmed
The present 90 - day toxicity study in F344 / DuCrlCrj rats was conducted for safety assessment and to determine a no observed adverse effect level ( NOAEL ) of L - asparagine . - pubmed
The NOAEL was determined to be 2.5 % in the diet ( males , 1.65 g / kg body weight / day ; females , 1.73 g / kg body weight / day ) . - pubmed
PURPOSE : We aimed to describe computed tomography ( CT ) findings in patients with peritoneal , omental and mesenteric lymphoma involvement . - pubmed
MATERIALS AND METHODS : We searched our archive retrospectively to find out patients with peritoneal , omental and mesenteric lymphoma involvement . - pubmed
We found 16 patients with non - Hodgkin lymphoma meeting these criteria . - pubmed
CT studies of these patients were reevaluated for the presence of peritoneal involvement , ascites , omental mass , organomegaly , retroperitoneal lymphadenopathy , bowel wall thickening and other associated findings . - pubmed
RESULTS : There were 14 males and 2 females with peritoneal and/or mesenteric and omental lymphoma involvement . - pubmed
Ascites was seen in 12 ( 75 % ) patients . - pubmed
Bowel wall thickening , retroperitoneal lymphadenopathy and hepatosplenomegaly were also common and observed in 10 , 10 and 11 patients , respectively . - pubmed
Solid organ involvement in the form of liver and splenic lesions was seen in 9 ( 56 % ) patients . - pubmed
MATERIALS AND METHODS : Ninety - two consecutive patients with cirrhosis underwent three - phase CT and endoscopy . - pubmed
RESULTS : Nine patients of 92 patients with cirrhosis were excluded because of previous procedure or motion artifact ; the remaining 83 patients with cirrhosis were evaluated . - pubmed
In the cirrhosis group , 40 ( 48.1 % ) of 83 patients showed the transient gastric perfusion defect sign . - pubmed
In the cirrhotic group , the frequency of the transient gastric perfusion defect sign was significantly higher in the patients with PHG ( 75 % , 36/48 ) than in patients without PHG ( 11.4 % , 4/35 ) . - pubmed
CONCLUSION : The transient gastric perfusion defect sign could be used as a relatively specific sign of PHG in patients with cirrhosis . - pubmed
The potential of the nematode Caenorhabditis elegans , the fruitfly , Drosophila melanogaster and the zebrafish , Danio rerio , as model genetic organisms for the study of human muscle disease is discussed by examining their muscle biology , muscle genetics and development . - pubmed
It is concluded that these organisms have already demonstrated potential in facilitating the study of muscle disease and in screening for therapeutic agents . - pubmed
Retrospective comparative study of 80 consecutive patients treated with either anterior cervical discectomy fusion ( ACDF ) or anterior cervical corpectomy fusion ( ACCF ) for multi - level cervical spondylosis . - pubmed
We evaluated 80 consecutive patients who underwent surgery for the treatment of multi - level cervical spondylosis at our institution from 1998 to 2001 . - pubmed
There was one patient in Group 1 and 2 patients in Group 2 with pseudarthroses . - pubmed
METHODS : This was a retrospective review of 204 emergency department pediatric patients presenting between January 1 , 2005 and February 28 , 2006 with appendicular trauma , with initially negative radiographic result and follow - up . - pubmed
An estimated 750 million people are at risk of infections with food - borne trematodes , which comprise liver flukes ( Clonorchis sinensis , Fasciola gigantica , Fasciola hepatica , Opisthorchis felineus , and Opisthorchis viverrini ) , lung flukes ( Paragonimus spp . ) - pubmed
Family - based randomized trial to detect effects on blood pressure of a salt substitute containing potassium and calcium in hypertensive adolescents . - pubmed
SETTING & amp ; PARTICIPANTS : 423 patients with CKD ( stages 4 - 5 ) were randomly assigned between January 1999 and January 2003 and followed up until December 2006 or death . - pubmed
3 patients ( 0.7 % ) met criteria for protein - caloric malnutrition . - pubmed
Effect of virgin olive oil plus acetylsalicylic acid on brain slices damage after hypoxia - reoxygenation in rats with type 1 - like diabetes mellitus . - pubmed
Aspirin is the most widely used drug for the secondary prevention of ischemic stroke in patients suffering from diabetes mellitus . - pubmed
The aim of the present study was to determine the possible influence of VOO administration to streptozotocin - diabetic rats ( DR ) on the neuroprotective effect of aspirin in rat brain . - pubmed
The main conclusion of our study is that daily oral administration of VOO to diabetic rats may be a natural way to increase the neuroprotective effect of aspirin in diabetic animals . - pubmed
Rabbit syndrome ( RS ) is an involuntary movement disorder characterized by rapid , fine movements of an individual 's mouth , similar to the chewing movements of a rabbit , and has most frequently been associated with the use of antipsychotic medications . - pubmed
In particular , recent advances in the study on the earliest phase of HIV-1 infection unearthed novel challenges for HIV vaccine development . - pubmed
The effect of antigens of Bordetella pertussis and their antibodies on brain infections by B. - pubmed
Antisera to whole cell vaccines whether they contain the ; bactericidal antigen ' or not , or the protective antigen or not can more easily reduce infections by mechanism ( 1 ) , eliminating small lethal challenges in some mice which are protected . - pubmed
Information about the effect of CCBs on incident HF in patients with hypertension is scarce . - pubmed
Trials of renal transplantation patients , placebo - controlled trials , and HF trials were excluded . - pubmed
The analysis indicated a significant increase in the diagnosis of HF in patients allocated to CCBs ( odds ratio 1.18 , 95 % confidence interval 1.07 to 1.31 ) . - pubmed
Furthermore , we observe that this defect is manifest early in infection , as M. - pubmed
Estivoautumnal ( Plasmodium falciparum ) malaria ; a survey of four hundred and ninety - three cases of infection with Plasmodium falciparum in children . - pubmed
Anterior uveal spindle cell tumor in a cat . - pubmed
PURPOSE : To describe a case of anterior uveal spindle cell tumor in a cat with features similar to spindle cell tumor of blue eyed dogs . - pubmed
METHODS : A 10 - year - old female spayed domestic short - haired cat was referred for an iris mass OS . - pubmed
The cat was lost to follow - up for 2 years , after which time she re - presented with glaucoma , blindness and grossly evident iridal mass enlargement OS . - pubmed
CONCLUSIONS : Based on its histopathologic characteristics , this iris tumor was diagnosed as a Schwann cell variant of a peripheral nerve sheath tumor ( PNST ) closely resembling the spindle cell tumor of blue - eyed dogs . - pubmed
Anterior uveal PNST has not been previously reported in cats to the authors ' knowledge . - pubmed
Therefore , dietary astaxanthin heightened cell - mediated and humoral immune response and reduced DNA damage and inflammation in dogs . - pubmed
RESULTS : Twenty patients ( 16 men ) with sinonasal adenocarcinoma were found . - pubmed
beta - arrestin deficiency protects against pulmonary fibrosis in mice and prevents fibroblast invasion of extracellular matrix . - pubmed
MATERIALS AND METHODS : A total of 20 male Wistar rats ( aged 3 months ) were divided into 2 groups : ( i ) control group fed with distilled water and ( ii ) experimental group fed with TRF ( 200 mg/ kg body weight ) for 8 months . - pubmed
A survey of ocular abnormalities in miniature horses . - pubmed
OBJECTIVE : To determine the incidence of ocular abnormalities in miniature horses . - pubmed
One miniature horse also had multiple ocular abnormalities ( cornea globosa , goniosynechiae , decreased or absent and pupillary light reflexes , miotic and dyscoric pupils , iris hypoplasia , and epinuclear cataract ) . - pubmed
Ocular abnormalities were observed in horses that had a flaxen or white mane and tail color and a chocolate coat color . - pubmed
CONCLUSIONS : Abnormal ocular phenotype detected in eyes of Miniature Horses was similar to multiple congenital and hereditary ocular abnormalities reported in the Rocky Mountain Horse . - pubmed
The authors highlight the unique contribution of the lymphatics to wound healing , as well as the unique contribution of OMT to lymphatic - directed treatment of patients with chronic wounds . - pubmed
The authors propose that this information be used as a basis for research into the effects of OMT on chronic wound healing in patients . - pubmed
Claudication pain in the left arm of a coronary artery bypass graft patient using crutches : Coronary subclavian steal syndrome - a case report . - pubmed
The pups were weaned for 21 days , and 6 weeks after the injection of STZ , the animals were checked for fasting glucose level ( FPG ) & gt;=160 mg / dl were considered as diabetic . - pubmed
RESULTS : Significant and dose - dependent correction of postprandial and fasting hyperglycemia was observed in diabetic rats following 8 weeks of chronic therapy . - pubmed
Dual thienopyridine low - response to clopidogrel and prasugrel in a patient with STEMI , cardiogenic shock and early stent thrombosis is overcome by ticagrelor . - pubmed
Little is known about the antiplatelet action of the thienopyridines , clopidogrel and prasugrel , as well as the non - thienopyridine , ticagrelor , in patients suffering from ST - elevation myocardial infarction ( STEMI ) complicated by cardiogenic shock since systematic comparisons of these antiplatelet agents in this devastating condition are limited so far . - pubmed
This is a report of a patient with STEMI undergoing urgent PCI in cardiogenic shock followed by repeated angioplasty after suffering early stent thrombosis ( ST ) who showed dual thienopyridine treatment failure of clopidogrel and prasugrel , which was successfully overcome by switching the patient to the non - thienopyridine derivative ticagrelor . - pubmed
UNLABELLED : A series of nitroderivatives has been synthetized from natural and synthetic olive oil phenols to increase the assortment of compounds with a putative effect against Parkinson disease . - pubmed
Deficits in social behavior emerge during development after pediatric traumatic brain injury in mice . - pubmed
The current study evaluated social behavior in mice subjected to TBI at post - natal day ( p)21 . - pubmed
TBI mice also lacked a preference for social novelty , suggestive of a deficit in social recognition or memory . - pubmed
This emergence of aberrant social behavior , which parallels the development of other cognitive deficits in this model and behaviors seen in brain - injured children , is consistent with the hypothesis that the full extent of deficits is not realized until the associated skills reach maturity . - pubmed
BACKGROUND : Ramadan fasting for pregnant women with diabetes remains controversial and underreported . - pubmed
METHODS : This was a retrospective study carried out over a period of three years including pregnant diabetic women , who were on short - acting , intermediate - acting , or a combination of them , and opted to carry out Ramadan fasting . - pubmed
These two markers were the best in detecting patients with lymph node metastases . - pubmed
In conclusion , this comparative study established that p - proteasome quantification in combination with other melanoma biomarkers is an attractive approach for the biological follow - up of melanoma patients . - pubmed
Apparent mineralocorticoid excess syndrome : report of one family with three affected children . - pubmed
In patients with AME , this ratio is 5 - 18 , while in normal individuals it is & lt;0.5 . - pubmed
The finding of abnormally high ratios of 24 - h urine - free cortisol to cortisone in our three patients ( case 1 , 8.4 ; case 2 , 25 ; and case 3 , 7.5 ) confirmed the diagnosis of apparent mineralocorticoid excess syndrome in these children . - pubmed
A case of recurrent labial adhesions in a 15 - month - old child with asymptomatic non - classic congenital adrenal hyperplasia due to 21 - hydroxylase deficiency . - pubmed
This report presents the case of a 15 - month - old girl with recurrent labial adhesions and urinary tract infections . - pubmed
BACKGROUND : A role for Epstein Barr virus ( EBV ) in multiple sclerosis ( MS ) has been postulated . - pubmed
PURPOSE : Postoperative respiratory failure is a major problem which can prolong the stay in the intensive care unit in patients undergoing cardiac surgery . - pubmed
The human vertebral body and intervertebral disc interface forms the region where the cartilaginous endplate , annulus fibrosis and bone of the vertebral body are connected through an intermediate calcified cartilage layer . - pubmed
The hypercoagulability of patients with nephrotic syndrome could be an important trigger for arterial and venous thrombotic events . - pubmed
Here we report the case of a patient with stroke as first manifestation of nephrotic syndrome . - pubmed
: Of men , not mice , and inflammation . - pubmed
PATIENTS AND METHODS : Thirty - six patients with displaced proximal humerus fractures from two centers were operated using locking plate . - pubmed
In one of the 18 displaced proximal humerus fractures of IMS ( + ) group , the head - shaft angle was measured to be & lt;125 , whereas six patients had varus deviation in IMS ( - ) group at follow - up ( p & lt ; 0.05 ) . - pubmed
A computed tomography scan of the patient , who had sustained an impact injury to the right occipital region , showed no cerebral lesion . - pubmed
Therefore , close ophthalmological and radiological evaluation is required in patients with TBI , in order to enable the diagnosis of Terson syndrome and an early vitrectomy . - pubmed
BACKGROUND : Infection may trigger clinically overt mucosal inflammation in patients with predisposition for inflammatory bowel disease . - pubmed
MNV might thus trigger overt clinical disease in individuals with a nonsymptomatic predisposition for inflammatory bowel disease by impairment of the intestinal mucosa . - pubmed
Fifty - seven patients of 58 studies confirmed the final diagnosis of bowel obstruction by surgical proof or obstructive symptoms relief from conservative treatments ; divided into 25 small bowel and 33 large bowel obstructions . - pubmed
Granuloma malignum ( Hodgkin ' s disease ) in the fin whale Balaenoptera physalus ) . - pubmed
Thus , a determination of an effective fluoride dentifrice may be beneficial in the reduction of the erosive process in patients with gastric disorders . - pubmed
Efficacy of just - in - time plerixafor rescue for Hodgkin ' s lymphoma patients with poor peripheral blood stem cell mobilization . - pubmed
Limited information is available on its use in Hodgkin ' s lymphoma ( HL ) patients . - pubmed
We describe our experience with plerixafor as an immediate rescue agent in HL patients with poor PBSC mobilization . - pubmed
CONCLUSION : Plerixafor can be used in HL patients with poor mobilization as a rescue agent and boosts mobilization sufficiently in most patients in the same collection attempt , thus not only permitting ASCT , but also avoiding remobilization and the associated costs , treatment delays , and patient inconvenience . - pubmed
Liver transplantation ( LT ) is the only curative treatment modality for patients with HPS . - pubmed
This case report describes a patient with typical findings of an extracardiac pulmonary arteriovenous shunt on contrast - enhanced transesophageal echocardiography ( TEE ) , and clubbing fingers , who had complete correction of HPS by deceased donor LT . - pubmed
Mortality is three to four times higher in a patient with coagulopathy and thus prevention and correction of coagulopathy is the central goal of the management of hemorrhagic shock in trauma . - pubmed
Acetylcholine serves as a derepressor in Loperamide - induced Opioid - Induced Bowel Dysfunction ( OIBD ) in zebrafish . - pubmed
This 31 - year - old woman presented with typical right trigeminal neuralgia caused by a trigeminocerebellar artery , manifesting as pain uncontrollable with medical treatment . - pubmed
The neuralgia resolved after the surgery ; the patient had slight transient hypesthesia , which fully resolved within the 1st month after surgery . - pubmed
CONCLUSION : Tobacco use caused one out of six deaths in Casablanca in 2012 . - pubmed
Early clinical improvement under antidepressant medication in the first 2 weeks of treatment is one of the best predictors for the long - term treatment outcome in patients with major depressive disorder . - pubmed
In this study , lamellar morphology and pathology were described in 14 laminitic horses and ponies that had hyperinsulinemia ( & gt;20 mIU / l ) , with reference to 25 age- and breed - matched controls . - pubmed
PARTICIPANTS : One hundred eight fellow untreated eyes of 143 patients with GA resulting from AMD enrolled in the MAHALO study ( clinicaltrials.gov identifier , NCT01229215 ) who completely satisfied the study term and had gradable spectral - domain optical coherence tomography ( OCT ) images obtained at both baseline and month 18 visits . - pubmed
METHODS : The MAHALO study enrolled 143 subjects into a phase 1b/2 multicenter , randomized , single - masked , sham - injection controlled clinical trial of the safety , tolerability , and evidence of activity of lampalizumab in patients with GA associated with AMD . - pubmed
The present study reports our experience with five renal cell carcinoma ( RCC ) patients with brain metastases treated with sunitinib and radiotherapy . - pubmed
After treatment with sunitinib , shrinkage of brain metastases was achieved in all patients with complete response , partial response and stable disease in two , one and two patients , respectively . - pubmed
Although progression of brain metastases occurred in four of the five patients , additional gamma - knife surgery was effective in three patients . - pubmed
The remaining one patient died of disease progression . - pubmed
Despite the observation of several adverse events after treatment with sunitinib , there was no intracerebral hemorrhage in any patient . - pubmed
These findings suggest that sunitinib combined with radiation therapy can be safely carried out in RCC patients with brain metastases and provides a favorable prognosis in these cases . - pubmed
However , considering their frequent progression , it would be important to carry out careful follow up for these patients by focusing on the control of brain metastases . - pubmed
Quantification of filamentation by uropathogenic Escherichia coli during experimental bladder cell infection by using semi - automated image analysis . - pubmed
Evidence has emerged over the past decade suggesting that this morphological transformation is controlled and reversible and provides selective advantages under certain growth conditions , such as during infection in humans . - pubmed
Used in combination with a flow - chamber based in vitro cystitis model , we study the factors involved in filament formation by uropathogenic E. - pubmed
coli ( UPEC ) during infection . - pubmed
MicroRNA-22 - 3p is down - regulated in the plasma of Han Chinese patients with premature ovarian failure . - pubmed
PATIENT(S ): A total of 140 individuals with premature ovarian failure ( POF ) and 140 age- and body mass index - matched control subjects of Han Chinese ancestry . - pubmed
RESULT(S ): Fifty - one differentially expressed miRNAs were identified by chip - based discovery stage between ten patients with POF and ten control subjects , among which nine miRNAs ( let-7b-5p , let-7c , miR-15b-5p , miR-22 - 3p , miR-23a-3p , miR-23b-3p , miR-24 - 3p , miR-151a-5p , and miR-151b ) were selected and validated . - pubmed
Correction : Impact of Maternal HIV Seroconversion during Pregnancy on Early Mother to Child Transmission of HIV ( MTCT ) Measured at 4 - 8 Weeks Postpartum in South Africa 2011 - 2012 : A National Population - Based Evaluation . - pubmed
METHODS : From 2009 to 2013 , ten patients with single - level Kummell ' s disease accompanied by severe osteoporosis were enrolled in this study . - pubmed
No patient sustained adjacent fractures after bone cement - augmented percutaneous short segment fixation during the follow - up period . - pubmed
SUBJECTS / METHODS : We examined 81 well - characterized normoglycemic men and postmenopausal women ( & gt;=27 kg m(-2 ) , 45 - 74 years , non - smokers , sedentary , free of chronic disease ) . - pubmed
Many species in this genus , including Pseudo - nitzschia multistriata , can produce domoic acid , a toxin responsible for amnesic shellfish poisoning . - pubmed
Resistance evaluation of Chinese wild Vitis genotypes against Botrytis cinerea and different responses of resistant and susceptible hosts to the infection . - pubmed
When validated with occurrence records for malaria , An . - pubmed
Bedside inferior vena cava filter placement by intravascular ultrasound in critically ill patients is safe and effective for an extended time . - pubmed
BACKGROUND : Bedside inferior vena cava filter ( IVCF ) placement by intravascular ultrasound ( IVUS ) guidance has previously been shown to be a safe and effective technique , especially for critically ill patients , with initial experience of a prospectively implemented algorithm . - pubmed
The purpose of this study was to evaluate the effectiveness of IVUS - guided filter placement in critically ill patients with experience now extending out 5 years from implementation . - pubmed
CONCLUSIONS : On the basis of 5 years of experience with bedside IVCF placement in critically ill patients , the IVUS - guided IVCF technique continues to be a safe and effective option in this high - risk population , with a time - dependent improvement in outcome measures . - pubmed
[ The influence of lumbar sympathetic ganglion radiofrequency thermocoagulation on the activation of microglia in rats with diabetic neuropathic pain ] . - pubmed
OBJECTIVE : To observe the influence of lumbar sympathetic ganglion radiofrequency thermocoagulation on the activation of spinal microglia in rats with diabetic neuropathic pain ( DNP ) . - pubmed
METHODS : Thirty - six painful diabetic Sprague - Dawley rats induced by 60 mg / kg streptozotocin ( STZ ) intraperitoneal injection were randomly divided into diabetic neuropathic pain group ( group DNP , n=12 ) , Sham operation group ( group Sham , n=12 ) and radiofrequency thermocoagulation group ( group R , n=12 ) . - pubmed
Topical administration of hyaluronic acid in children with recurrent or chronic middle ear inflammations . - pubmed
Hyaluronic acid ( HA ) treatment has been successfully performed in patients with recurrent upper airway infections or rhinitis . - pubmed
The aim of this study was to assess the efficacy and safety of the topical nasal administration of an HA - based compound by investigating its effects in children with recurrent or chronic middle ear inflammations and chronic adenoiditis . - pubmed
The reduction in the prevalence of patients with conductive hearing loss ( CHL ) ( P value = 0.008 ) and those with moderate CHL ( P value = 0.048 ) was significant in the study group , but not in the control group . - pubmed
Our findings confirm the safety of intermittent treatment with a topical nasal sodium hyaluronate solution and are the first to document its beneficial effect on clinical and audiological outcomes in children with recurrent or chronic middle ear inflammations associated with chronic adenoiditis . - pubmed
Closed - Loop Prevention of Hypotension in the Heartbeating Brain - Dead Porcine Model . - pubmed
Objective : The purpose of this paper is to demonstrate feasibility of a novel closed - loop controlled therapy for prevention of hypertension in the heartbeating brain - dead porcine model . - pubmed
Nearly half of all surgical patients have moderate to severe pain postoperatively , and 24 % experience inadequate pain relief . - pubmed
Furthermore , over half of the patients develop chronic pain after thoracotomies , mastectomies , and limb amputation surgeries . - pubmed
Human cytomegalovirus is a significant agent of hepatic involvement in neonates . - pubmed
PURPOSE : To determine changes in Achilles tendon resting angle ( ATRA ) , heel - rise height , patient - reported outcomes , return to play , and occurrence of complications after minimally invasive repair of Achilles tendon ruptures using nonabsorbable sutures . - pubmed
METHODS : Between March 2013 and August 2015 , a total of 70 patients ( 58 males , 12 females ) with a mean age of 42 + - 8 years were included and evaluated at 6 weeks and 3 , 6 , 9 , and 12 months after repair of an Achilles tendon rupture . - pubmed
Methods We conducted a multicenter , case - control study in which 15 RA patients who developed PCP were compared with 74 RA patients who did not develop PCP during etanercept therapy . - pubmed
Results PCP developed within 26 weeks following the first injection of etanercept in 86.7 % of the patients . - pubmed
In patients having a larger number of risk factors , the cumulative probability of developing PCP was significantly higher ( p & lt ; 0.001 for patients with two or more risk factors vs. those with no risk factor , and p = 0.001 for patients with one risk factor vs. those with no risk factor ) . - pubmed
Delayed recovery of the affected finger extensors at chronic stage in a stroke patient : A case report . - pubmed
RATIONALE : A 33 - year - old male presented with complete weakness of the right extremities due to corona radiata infarct . - pubmed
The putative benefit of perioperative seizure prophylaxis must be weighed against the risks of adverse effects and drug interactions in patients without a history of seizures . - pubmed
Consequently , the authors conducted a systematic review of prospective randomized controlled trials ( RCTs ) that have evaluated the efficacy of perioperative seizure prophylaxis among patients without a history of seizures . - pubmed
Further , this expected incidence of new - onset postoperative seizures would require a total of 1258 patients to enroll in a RCT , as determined by a Farrington - Manning noninferiority test performed at the 0.05 level using a noninferiority difference of 5 % . - pubmed
A large multicenter randomized clinical trial would be required to assess whether perioperative seizure prophylaxis provides benefit for patients undergoing brain tumor resection . - pubmed
The impact of volume overload on right heart function in end - stage renal disease patients on hemodialysis . - pubmed
PURPOSE : The aim of this study was to evaluate the impact of volume overload on echocardiographic parameters used for the assessment of the right ventricle ( RV ) and right atrium ( RA ) , to determine volume - independent parameters and to noninvasively investigate the physio - mechanics of RV and RA by examining end - stage kidney patients before and after hemodialysis ( HD ) . - pubmed
Materials and Methods : Using two multicenter retrospective studies on breast cancer , a pooled analysis was performed among 320 patients with pT1 - 2N1 TNBC . - pubmed
None of the patients developed recurrence or metastasis . - pubmed
This study aimed to retrospectively investigate the risk factors of LLN metastasis in clinical lymph node - negative ( cN0 ) PTC patients . - pubmed
Patients with tumor in the upper lobe had ~ 3 - fold higher risk of LLN metastasis compared with patients with tumor in other locations ( OR = 2.874 , 95 % CI 1.916 - 4.310 ; P = 0.001 ) . - pubmed
CONCLUSIONS : Large tumor size ( & gt ; 20 mm ) , tumor located in the upper lobe , multifocality , extrathyroidal extension , and & gt;= 2 CLN metastases may increase the risk of LLN metastasis in cN0 PTC patients . - pubmed
RU47 in two plant species ( potato and lettuce ) and its biocontrol effect against Rhizoctonia diseases . - pubmed
We aimed to assess all randomized controlled trials from the world literature for the purpose of evaluating the clinical outcome - specific efficacy of SCS for the following outcomes : perceived pain relief or change pain score , quality of life , functional status , psychological impact , analgesic medication utilization , patient satisfaction , and health care cost and utilization . - pubmed
AIMS : Anthracycline - based chemotherapy improves survival in breast cancer patients but is associated with increased risk of heart failure ( HF ) . - pubmed
METHODS AND RESULTS : Between 1990 and 1998 the Danish Breast Cancer Cooperative Group ( DBCG ) 89D trial randomized 980 Danish women with early breast cancer to adjuvant cyclophosphamide , epirubicin , and fluorouracil or cyclophosphamide , methotrexate , and fluorouracil . - pubmed
In the epirubicin treatment group , 23 new cases of HF were identified vs. 9 in the non - epirubicin group corresponding to incidence rates per 1000 patient - years of 3.7 [ 95 % confidence interval ( CI ) 2.5 - 5.6 ] vs. 1.4 ( 95 % CI 0.7 - 2.7 ) . - pubmed
Background : Elevated homocysteine ( Hcy ) has been reported to be associated with cardiovascular events in atrial fibrillation ( AF ) patients , while the age - related expression pattern of plasma Hcy in AF remains unknown . - pubmed
The study was aimed to investigate the effect of advanced age on plasma Hcy levels and its association with ischemic stroke in non - valvular AF patients . - pubmed
Methods : A total of 2562 consecutive patients with non - valvular AF and 535 controls were enrolled and divided into six age groups . - pubmed
Hcy was much higher in AF patients than in controls at the same age group ( all P & lt ; 0.05 ) . - pubmed
The proportion of patients with hyperhomocysteinemia increased gradually with age from 32.3 % , 29.2 % , 31.2 % , 32.4 % , 45.9 % , to 51.4 % in six age groups . - pubmed
The concentration of Hcy in AF patients with ischemic stroke increased progressively with age , and was higher than those without stroke at the same age . - pubmed
Conclusions : Advanced age was significantly associated with elevated Hcy levels , which may provide a possible explanation for the progressive increase in ischemic stroke especially in elderly AF patients . - pubmed
This study aimed to assess whether dienogest ( DNG ) is also effective in patients with recurrent endometriosis based on multicenter data of 121 women who were clinically diagnosed as having recurrent endometriosis and treated for more than 24 weeks with DNG ( 2 mg daily ) . - pubmed
In conclusion , DNG was found to be effective in reducing the size of endometriomas and provided symptomatic relief in this cohort of women with recurrent endometriosis . - pubmed
CONCLUSION : Increased anticholinergic load during hospitalization might be a predictor of increased AP in geriatric patients . - pubmed
Thus , studies on normal mammalian cells are necessary to identify cytotoxicity and prevent adverse effects of functional foods that contain these dyes . - pubmed
METHODS : A clinical pathway was created to aid in detecting patients expected to experience postextubation stridor and to guide prophylactic treatment . - pubmed
,CzechRepublic ) and Carboplatin in chemo - naive advanced non - squamous NSCLC Iranian patients . - pubmed
Conclusion : The combination of Formeta and Carboplatin was effective in advancednon - squamous NSCLC and can be a suitable candidate as first - line treatment in these patient 's population . - pubmed
Moreover , if humans respond similarly , we posit that individuals with specific mtDNA variations may differentially metabolise carbohydrates , which has implications for a variety of diseases including cardiovascular disease , obesity , and perhaps Parkinson ' s Disease . - pubmed
Comparison of hemodynamic parameters that can predict an aneurysmal rupture : 20 patient - specific models experiment . - pubmed
Relief of intractable pruritus with romidepsin in patients with cutaneous T - cell lymphoma : A series of four cases . - pubmed
The majority of patients with CTCL experience pruritus , which can interfere with daily activities , significantly impact quality of life , and is typically uncontrolled by standard anti - itch therapies . - pubmed
Here , we describe the cases of four patients with debilitating and refractory pruritus that were resolved with romidepsin . - pubmed
The potential for pruritus relief with romidepsin should be considered when treating patients with CTCL . - pubmed
Effect of occupation - based interventions in patients with haematopoietic malignancies undergoing chemotherapy : A pilot randomised controlled trial . - pubmed
Genetic analyses of human fetal retinal pigment epithelium gene expression suggest ocular disease mechanisms . - pubmed
MLST provides a powerful solution for molecular epidemiological characterization of bacterial strains , including Staphylococcus aureus , by using the sequences of the internal region of seven housekeeping genes . - pubmed
INTRODUCTION : This study investigates the outcomes and safety of 70 - 150 mum and 100 - 300 mum doxorubicin drug - eluting bead transarterial chemoembolisation ( DEB - TACE ) in patients with unresectable hepatocellular carcinoma ( HCC ) . - pubmed
METHODS : Retrospective , cohort study of 51 patients treated with DEB - TACE for unresectable HCC was studied : 23 with 100 - 300 mum particles and 28 with 70 - 150 mum particles . - pubmed
At 1 - month follow - up , patients treated with 70 - 150 mum had significantly better mRECIST tumour response compared to 100 - 300 mum ( complete response 38.5 % vs. 19 % ; partial response 57.7 % vs. 42.9 % ; stable disease 0 % vs. 4.8 % ; progressive disease 3.8 % vs. 33.3 % , P = 0.027 ) . - pubmed
Acute Generalized Exanthematous Pustulosis Caused by the Combination of Pembrolizumab Plus Chemotherapy in a Patient With Squamous - Cell Carcinoma . - pubmed
Itch ( pruritus ) , specifically chronic itch associated with disease conditions , significantly impairs the patient 's quality of life . - pubmed
Here , we report that intragastrical administration of bulleyaconitine A ( BLA ) , which has been used for treating chronic pain for 30 years in China , inhibited itch - like behaviors induced by intradermal injection of histamine and chloroquine in mice and rats , dose - dependently . - pubmed
BACKGROUND : Epilepsy is the most common chronic neurologic disorder which affects an estimated 10.5 million children worldwide . - pubmed
CONCLUSION : This study revealed that many children were suffering from uncontrolled seizure and escalation therapy is being exercised . - pubmed
Borrelia burgdorferi sensu stricto ( Bbss ) is considered the primary agent of Lyme disease in North America . - pubmed
However , multiple genetically diverse Borrelia species encompassing the Borrelia burgdorferi sensu lato ( Bbsl ) complex and the Relapsing Fever Borrelia ( RFB ) group are capable of causing tickborne disease . - pubmed
garinii ( 10 ) , and mixed infections that included B. - pubmed
In this analysis , three independent observers quantified and categorized the presence of TILs among tumor samples from patients in PlanB. - pubmed
CASE PRESENTATION : A 26 - year - old man , with a history of drug abuse and a victim of domestic violence as a child , presented with tonic - clonic seizures and intracranial hypertension three years ago , for which he underwent a craniotomy with the finding of a right frontal cerebral tuberculoma . - pubmed
Distinguishing mode of action of compounds inducing craniofacial malformations in zebrafish embryos to support dose - response modeling in combined exposures . - pubmed
Immunotherapy has revolutionized cancer treatment , yet most patients do not respond . - pubmed
METHODS : During 2014 to 2017 24 children and adolescents ( nine female , 15 male , median age 9.7 years ) , were treated for symptomatic urolithiasis in our institutions . - pubmed
SETTING : CMCO teaching hospital , Strasbourg University Hospitals , France PATIENTS : All patients presenting a single endometrial polyp of size greater than or equal to a centimeter . - pubmed
Detection of disability worsening in relapsing - remitting multiple sclerosis patients . - pubmed
BACKGROUND AND PURPOSE : In relapsing - remitting multiple sclerosis patients ( RRMS ) disability progressively accumulates over time . - pubmed
METHODS : A cohort of 7,964 RRMS patients followed for two or more years , with EDSS scores recorded every six months , was selected from the Italian Multiple Sclerosis ( MS ) Register . - pubmed
[ Congenital microvillus inclusion disease in a child ] . - pubmed
The association between seropositivity to human toxocariasis and childhood asthma in northern Iran : a case - control study . - pubmed
RESULTS : Seropositivity rate was 4.1 % ( 95 % CI , 3.4 - 4.7 % ) in asthmatic children and 0.86 % ( 95 % CI , 0.71 - 1.0 % ) in controls , suggesting a strong association ( P - value < 0.02 ) . - pubmed
Comparison of Effects Exerted by 4 % Articaine Buccal Infiltration and 2 % Lidocaine Inferior Alveolar Nerve Block on Pain Perception and Behavioral Feedback of Children during Pulp Treatment of Mandibular Second Primary Molars . - pubmed
Results : Of the 38 patients included in the current study , 10 ( 26.3 % ) subjects in the lidocaine group and nine ( 23.6 % ) in the articaine group complained of pain during their dental treatment procedures , but this difference was not statistically significant . - pubmed
PATIENT CONCERNS : A 55 - year - old woman presented to the outpatient general surgery department with severe , persistent abdominal pain . - pubmed
The patient was diagnosed with congenital absence of uterus and vagina , and a sigmoid vaginoplasty was performed 34 years ago . - pubmed
OUTCOMES : After surgery , the abdominal pain was relieved , and the patient reported full recovery during a 6 - month follow - up appointment . - pubmed
Surgical removal of neovagina can relieve the pain in patients who do not have the demand of sexual intercourse . - pubmed
A striking difference in the detection of a heavy growth of Streptococcus pyogenes in throat swabs taken from 1054 children with pharyngitis compared with those from 462 normal children was demonstrated when a standardised technique of quantitative culture was used . - pubmed
Patients with vascular disease of the legs were studied by indirectly measuring thigh and ankle systolic pressures and recording the femoral artery flow profile before and after exercise with the aim of identifying those patients in whom significant aortoiliac stenosis may not have been diagnosed by angiography . - pubmed
Resting thigh pressures were reduced in the group of patients with aortoiliac disease and with SFA occlusion . - pubmed
There was no significant change in thigh pressure with exercise in any group but ankle pressure fell with exercise in the patients with aortoiliac disease and with SFA occlusion . - pubmed
An unicellular alga , Chlorella pyrenoidosa , which had been reported to protect C3H mice against sarcoma BP8 , is shown , when injected in Freund 's incomplete adjuvant , to modulate the antibody synthesis induced by immunization with a hapten - carrier complex . - pubmed
Experimental hypersensitivity pneumonitis : reduced severity of clinical response following repeated injections of Micropolyspora faeni antigen . - pubmed
Methylphenidate and caffeine in the treatment of children with minimal brain dysfunction . - pubmed
In this double - blind , crossover study of 8 boys with minimal brain dysfunction , 20 mg of methylphenidate daily was significantly better than 160 mg of caffeine in controlling behavior , especially impulsivity and hyperactivity , and methylphenidate alone was superior to decaffeinated coffee and placebo . - pubmed
Sixteen men with well - documented angina pectoris and without previous myocardial infarction performed a multistage exercise stress test to determine their levels of exercise - induced limitations , characterized by onset of chest discomfort or electrocardiographic ischemic changes , or both . - pubmed
We have reported on a patient with isolated metachronous renal artery emboli . - pubmed
Influence of combined administration of ethyl alcohol with caffeine and hydroxyzine on cardiac minute volume and stroke volume in rabbits . - pubmed
However these changes were not observed in the positional tests of a group of 22 patients with hearing losses attributable to other causes . - pubmed
Nine patients with multiple metastases including liver from breast cancer were treated with transarterial chemoembolization through hepatic artery using 40 - 50 mg of 4 '- epi - adriamycin and Lipiodol , followed by 800 - 1,200 mg / day of medroxyprogesterone acetate . - pubmed
Seven out of 9 patients died within 6 to 37 months ( mean 15.3 months ) after diagnosis of liver metastases . - pubmed
Furthermore , we have been able to demonstrate an age related increase in lymphoproliferative responses to both PHA and tetanus in HIV - infected and control children . - pubmed
Longitudinal study of solute excretion and glomerular ultrastructure in an experimental model of aging rats free of kidney disease . - pubmed
In the oldest animals a few foci of interstitial inflammation occasionally were seen . - pubmed
These observations indicate that basic age - related changes in kidney structure and function of rats fed ad libitum can be reduced to a few parameters provided that adequate strains , diet , and husbandry conditions are selected for experimentation . - pubmed
Observations of impaired chondrocyte metabolism in essential fatty acid ( EFA ) deficiency as well as EFA protection against development of osteoarthrosis in inbred mice suggest the existence of a relationship between EFA , chondrocyte metabolism , and cartilage degeneration . - pubmed
For all assays , performance declined markedly in 1 degree HPT patient groups with lower serum calcium levels . - pubmed
Eighteen patients with end - stage symptoms of primary sclerosing cholangitis were evaluated during a 10 - year period from 1976 to 1986 . - pubmed
All patients presented with elevated liver function test results , and six of nine patients had a history of ulcerative colitis . - pubmed
Two of three of the patients with biliary cirrhosis died within 1 year after surgery . - pubmed
For patients with end - stage primary sclerosing cholangitis , intrahepatic cholangiojejunostomy provides effective surgical palliation in those without secondary biliary cirrhosis . - pubmed
Habituation of the pain perception threshold was found for control subjects but not for CLBP patients . - pubmed
A 63 - year - old white man with metastatic small cell carcinoma of the bladder attained a complete remission with a combination of etoposide and cisplatin chemotherapy , which has lasted for more than 2 years . - pubmed
Characteristics of an ovariectomized osteopenic rat model . - pubmed
Although osteoporosis induced by ovariectomy ( Ovx ) in the rat has been widely used as a model for postmenopausal osteoporosis in humans , the findings of different investigators are not always consistent . - pubmed
The effects of Ovx on body weight , femoral length , and femoral volume were marked in rats operated on at the age of 4 weeks , slight in rats operated on at the age of 52 weeks , and intermediate in rats operated on at the age of 10 weeks . - pubmed
Spontaneous electrophysiological activity and excitation by capsaicin of regenerating sensory fibers has been studied using 1 to 20 - week - old neuromas induced in rats by ligating and transecting the saphenous nerve . - pubmed
Patients with gastric disorders and those taking medications that affect gastric motility or secretion were excluded . - pubmed
Administration of antibody , directed against glomerular basement membrane ( GBM ) heparan sulfate - proteoglycan , into a presensitized rat results in the induction of membranous nephropathy with subepithelial immune - complex deposits . - pubmed
A beta - carboline antagonizes benzodiazepine actions but does not precipitate the abstinence syndrome in cats . - pubmed
Kappa light chain myeloma developing in a patient with chronic neutrophilic leukaemia . - pubmed
Antibodies to indigenous and laboratory strains of Streptococcus mutans in saliva from children with dental caries and from caries - free children . - pubmed
Effective clinical use has been demonstrated in patients with cutaneous and systemic candidiasis , aspergillosis , blastomycosis , coccidioidomycosis , cryptococcus and systemic candidiasis , aspergillosis , blastomycosis , coccidioidomycosis , cryptococcus and histoplasmosis . - pubmed
We report our experience with the oral imidazole agent ketoconazole in the management of 8 patients with significant urinary candidiasis as judged by elevated urinary candidal counts ( greater than 15,000 / ml . ) - pubmed
Only 4 of the 8 patients had resolution of candiduria with ketoconazole therapy . - pubmed
[ Immunochemical properties of a soluble immune complex from the blood serum of cancer patients ] . - pubmed
The immunologic status of 18 patients with intestinal lymphangiectasia was studied . - pubmed
Primary circulating antibody response was tested in five patients with Vi and tularemia antigens . - pubmed
Titers elicited in patients with the Vi antigen were significantly lower than those seen in a control group , whereas no difference was seen between patient and control responses to the tularemia antigen . - pubmed
Lymphocytopenia was noted in patients with intestinal lymphangiectasia . - pubmed
91 % of normal individuals reacted to at least one of the four skin test antigens : purified protein derivative , mumps , Trichophyton , and Candida albicans ; in contrast , only 17 % of patients with intestinal lymphangiectasia had a positive reaction . - pubmed
The humoral antibody response to a primary viral neoplasm ( MSV ) through its entire course in BALB - c mice . - pubmed
[ Partial and generalized convulsive manifestations of stereotaxic lesions of the brainstem in the cat ] . - pubmed
[ Electron microscopic studies under neurophysiologic control of brain edema in cats ] . - pubmed
Morphogenesis of the eye lens in a mouse strain with hereditary cataracts . - pubmed
[ Serum complement profile and its clinical significance in patients with hepatocellular carcinoma and liver cirrhosis ( author 's transl ) ] . - pubmed
Growth retardation and renal osteodystrophy in children with chronic renal failure . - pubmed
Height , expressed as standard deviation scores for chronological age and for bone age , was studied in relation to glomerular filtration rate , bone age delay , and bone histology in 47 children with chronic renal disease and GFR less than 80 ml / min/1.73 m2 . - pubmed
Renal osteodystrophy , which only occurred at GFR less than 30 ml / min/1.73 m2 , significantly affected height only in children with congenital renal disease and GFR less than 20 ml / min/1.73 m2 . - pubmed
The pathophysiological effects of experimental larval challenge with a mixed trichostrongyle infection were measured in ewes which had previously grazed contaminated pasture . - pubmed
Lymphocyte response in mice infected with the Indonesian and Formosan strains of Schistosoma japonicum to concanavalin A , and to worm and egg antigens . - pubmed
The differences may have been associated with the number of worms developing in the mice since the adult worm recovery for the Indonesian strain was nearly twice that of recoveries from mice infected with the Formosan strain . - pubmed
Peripheral blood mononuclear cells ( PBMC ) from 12 patients with Graves ' disease and 9 healthy subjects were cultured with peptides for 3 days . - pubmed
Four hundred forty - five bronchoalveolar lavage specimens from patients with the human immunodeficiency virus were preserved in Saccomano 's fixative and stained for Pneumocystis carinii cysts by a modified method with Fungi - Fluor Solution A ( Polysciences , Warrington , Pa ) and the Genetic Systems Pneumocystis carinii Immunofluorescence Antibody ( Genetic Systems Corp , Seattle , Wash ) . - pubmed
The sensitivity for detecting cysts of P carinii was significantly greater with the Genetic Systems stain ( P & lt ; .01 ) . - pubmed
However , there is clear evidence that the incidence of such vessels in patients with ureteropelvic junction obstruction is significantly higher than in the general population . - pubmed
Bacterial translocation : nursing implications in the care of patients with neutropenia . - pubmed
PURPOSE / OBJECTIVES : To describe bacterial translocation ; the potential causes and influencing factors of bacterial translocation ; the anatomy , physiology , and immunology of the small intestine ; and the significance of bacterial translocation in patients with cancer . - pubmed
This process called bacterial translocation may be responsible for symptoms such as fever of unknown origin in these patients . - pubmed
[ Generation of active forms of oxygen by alveolar macrophages in patients with bronchial asthma ] . - pubmed
Exercise - induced changes in oxygen saturation in the calf muscles of elderly subjects with peripheral vascular disease . - pubmed
In summary , NIRS measurements show promise as a method of evaluating the kinetics of oxygen saturation , particularly in patients with mild peripheral vascular disease . - pubmed
The immediate hematopoietic response to 3 '- azido-3 '- deoxythymidine ( AZT ) was characterized in an unperturbed and regenerating mouse marrow model to identify the in vivo hematopoietic targets of AZT and test whether AZT toxicity is dependent on the proliferative activity of the hematopoietic targets . - pubmed
When administered to mice whose marrow was regenerating from total - body irradiation ( TBI ) and subsequent bone marrow transplantation ( high proliferative fraction ) , 240 mg / kg AZT caused considerable reductions of all hematopoietic cell stages even when given as a single IV injection . - pubmed
The morphological and physiological properties of this strain suggest that it belongs to the genus Arthrobacter , and the isolate was therefore designated Arthrobacter strain 45 - 8A. - pubmed
They are also indistinguishable from antibodies induced by a proposed vaccine to cholesterol that is currently in late preclinical development for prevention of hypercholesterolemia in humans . - pubmed
Observation of baker 's yeast strains used in biotransformation by atomic force microscopy . - pubmed
In those persons having taken 131J , frequency of the thyroid gland neoplasia gets increased almost 6 - fold as compared to general population . - pubmed
Thirty patients ( 18 men , 12 women , mean age 56 + /- 12 years ) with systemic amyloidosis verified by biopsy and strong indications of cardiac amyloidosis comprised the study group , with 30 healthy age- and sex - matched individuals serving as controls . - pubmed
All patients and controls underwent 24 - h Holter monitoring for arrhythmias . - pubmed
Left ventricular ( LV ) wall thickening was found in all patients with cardiac amyloidosis . - pubmed
The LV mass in the patients with cardiac amyloidosis was significantly greater than that of the control group , as was the ratio LV mass / body surface area ( p & lt ; 0.001 ) . - pubmed
changes in biochemical markers of bone formation and resorption were comparable in patients with quadriplegia and paraplegia , except for a greater increase in quadriplegics in pyridinoline , expressed as a percentage of baseline . - pubmed
Subjects were assessed at regular intervals with the Yale - Brown Obsessive Compulsive Scale Modified for BDD ( BDD - YBOCS ) , the Clinical Global Impressions ( CGI ) scale , the Hamilton Rating Scale for Depression , the Brown Assessment of Beliefs Scale , and other measures . - pubmed
We report 2 cases of primary muscular hydatosis of the thigh in a 30 - year - woman and a 75 - year - man . - pubmed
OBJECTIVE : To compare the efficacy of intranasally administered azelastine to budesonide , at their respectively recommended dosage , on the symptoms of perennial rhinitis patients . - pubmed
The 195 patients ( with at least a 2 - year history of perennial allergic rhinitis ) recorded individual nasal symptom scores , the degree of symptom control achieved and any adverse events experienced over a 2 - week baseline period and a 6 - week treatment period . - pubmed
In patients treated with budesonide , there were also significantly larger reductions from baseline values in combined nasal symptom scores ( P & lt ; .01 ) and in scores for all individual nasal symptoms ( P & lt ; or = .05 ) compared with those treated with azelastine . - pubmed
Nonsteroidal anti - inflammatory drugs ( NSAIDs ) have been shown to cause apoptosis in several cell lines including transformed chicken embryo fibroblasts and human colon cancer cells . - pubmed
The authors present results of manifold evaluation of stomach in 109 patients with vibration disease caused by various vibration characteristics . - pubmed
Usefulness of the electrocardiogram in predicting stent patency in patients presenting with chest pain within one month of coronary stenting . - pubmed
Considering the experimental work on paracoccidioidomycosis , 0.03 ml of a fungal suspension obtained from a biopsy of a Jorge Lobo ' s Disease patient were inoculated into both hind foot pads of 32 six week - old BALB / c mice of both sexes . - pubmed
Based on fungal count , viability index before and after inoculation , presence of macroscopic lesions and histopathological findings similar to the findings in humans , the authors believe that BALB / c mice may be a good experimental model to study Jorge Lobo ' s Disease , mainly regarding therapeutic evaluation . - pubmed
Microinjection through the round window membrane has been found to represent a method for vector delivery in intracochlear gene transfer in animal models but breaches the round window membrane , making it necessary to evaluate animals for possible postinjection hearing loss . - pubmed
In this preliminary study saline microinjection through the round window membrane did not cause permanent hearing loss in the guinea pigs tested , and any damage caused by microinjection appeared to be reversible . - pubmed
We describe the clinical course of a series of patients who developed agranulocytosis while taking this drug , and we estimate the risk by means of both a case - control and a case - population strategy . - pubmed
From July 1994 to December 1996 , 41 patients with previously untreated , advanced bulky squamous cell carcinoma arising from the buccal mucosa ( BSCC ) were enrolled . - pubmed
PATIENTS : Biopsies were taken in 13 patients with tumors of the petrous apex and petroclival region . - pubmed
Three other patients had metastases ( carcinoma of the breast , bronchial carcinoma , and unknown origin ) . - pubmed
Three patients had a meningioma , and another three a chordoma . - pubmed
OBJECTIVE : To describe an approach to the treatment of eruptive syringomas in an African American patient with a combination of trichloroacetic acid ( TCA ) and CO2 laser resurfacing , providing acceptable cosmetic results without significant side effects . - pubmed
METHODS : We describe an African American patient with eruptive syringomas of the face treated with a combination of TCA and CO2 laser resurfacing with good results . - pubmed
The resistances to starvation , paraquat , and cold in flies from 1 to 7 week - old have been measured . - pubmed
Breast MR imaging is a useful tool for staging breast cancer patients , and staging is more accurate with MR imaging than with conventional imaging techniques . - pubmed
Bile acids derived from intestinal bacterial metabolism and transported to the breast in plasma may influence risk of breast cancer . - pubmed
Suppression of intestinal polyposis in Apc ( Min /+ ) mice by inhibiting nitric oxide production . - pubmed
The genome of Rickettsia tsutsugamushi was detected and identified as the Kawasaki serotype strain . - pubmed
Renal scarring caused by vesicoureteric reflux and urinary infection : a study in pigs . - pubmed
The mechanisms of reflux nephropathy scarring are best explained by a piglet model in which vesicoureteric reflux allows infected urine to enter those segments of renal parenchyme that are drained by compound papillae . - pubmed
Adult pigs were exposed to urine infection after surgery to produce unilateral vesicoureteric reflux . - pubmed
One week later Escherichia coli was injected into the urinary bladder to produce cystitis . - pubmed
The risk of reflux nephropathy scarring is not eliminated by maturation of the kidney in pigs . - pubmed
It is unlikely that the much - reduced risk of initiating scarring that is seen in older children with urine infections is due to a protective maturation of the human kidney . - pubmed
A possible explanation is that most children born with risk factors for developing scarring will have already sustained scars when very young . - pubmed
The lung , the organ that is predominantly responsible for the morbidity and mortality in CF patients , is accessible by a non - invasive method , the inhalation of aerosols . - pubmed
PURPOSE : To describe a combined pharmacological and surgical approach to treating acquired nystagmus in a patient with multiple sclerosis . - pubmed
METHODS : A 40 - year - old patient with acquired horizontal and vertical nystagmus and severe oscillopsia secondary to multiple sclerosis had combined treatment with gabapentin and a vertical Kestenbaum - type procedure . - pubmed
RESULTS : After gabapentin treatment ( 3,000 mg orally daily ) the horizontal nystagmus was significantly reduced , and the patient developed a marked chin - up position . - pubmed
In particular , comprehension is dependent on anterolateral and ventral left temporal regions , as suggested by observations on patients with semantic dementia , as well as posterior regions described in studies on aphasic stroke patients . - pubmed
The only frontal contribution was confined to the ventrolateral left prefrontal cortex , compatible with observations that comprehension of simple speech is preserved in patients with left posterior frontal infarction . - pubmed
Magnetic resonance imaging in patients diagnosed with ductal carcinoma - in - situ : value in the diagnosis of residual disease , occult invasion , and multicentricity . - pubmed
The most significant mode of infection by the inhabitants was the raw eating of sweetfish which commonly harbour metacercariae of M. - pubmed
The infection in the sweetfish Plecoglossus altivelis as the second intermediate host was first observed from May with low level of infection and the intensity of infection in a fish rapidly increased until reaching a peak in October when sweetfish season normally ends . - pubmed
[ Effect of phenadone on blood pressure in rabbits in experimental cholesterol arteriosclerosis and following implantation of heterogenous tissue ] . - pubmed
Infants with Ureaplasma urealyticum in the lower respiratory tract are at risk for chronic lung disease ( CLD ) or bronchopulmonary dysplasia ( BPD ) but causality has been difficult to prove . - pubmed
OBJECTIVE : The pathogenetic mechanism of tobacco - related cardiovascular diseases is still not well defined . - pubmed
Extracranial injuries including bone fractures were the most common associated injuries and medical complications such as spasticity and contractures were present in more than half of the patients . - pubmed
TBI survivors in this study made statistically significant functional improvements . - pubmed
Since the beverage was recently demonstrated to exert hypotensive effect in rats , we analyzed its underlying mechanisms in this study . - pubmed
The objectives of the current study were to evaluate the outcomes of patients with T2b , locally persistent NPC who were treated with high - dose - rate ( HDR ) intracavitary brachytherapy and to explore whether routine brachytherapy boost could improve the local control of patients who had T2b NPC at initial diagnosis . - pubmed
METHODS : Thirty - four patients with locally persistent NPC who were treated during 1992 - 2000 with HDR intracavitary brachytherapy were analyzed retrospectively . - pubmed
To compare the efficacy of brachytherapy , another 403 consecutive patients with nonmetastatic T2b NPC who were treated with curative intent by external radiotherapy ( ERT ) during the same period were evaluated . - pubmed
CONCLUSIONS : The results suggested that patients with T2b NPC who have locally persistent disease can be salvaged effectively with brachytherapy . - pubmed
METHODS : Five patients diagnosed as having pemphigus vulgaris and pemphigus foliaceus were treated with the monoclonal antibody rituximab . - pubmed
We extracted and isolated three natural styryl lactones from Goniothalamus griffithii Hook f. Thoms and investigated their cytotoxicity on a panel of three hepatocyte cell lines , HepG2 , drug resistant HepG2 ( HepG2 - R ) and primary cultured normal mice hepatocyte in order to find candidates of potential anti - cancer drugs which have low toxicity on normal cells and high effect on tumors or drug resistant tumors . - pubmed
All the three styryl lactones showed evident cytotoxic activities on both HepG2 and HepG2 - R cell lines ; however , gonithalamin and goniodiol shows less toxicity on normal mice hepatocyte as the IC(50 ) values of them on normal mice hepatocyte were about three times of that on HepG2 . - pubmed
METHODS : Seventeen eyes of 15 patients suffering from secondary glaucoma following pars plana vitrectomy underwent Ahmed valve implantation . - pubmed
Third - degree atrioventricular block in 21 cats ( 1997 - 2004 ) . - pubmed
The effect of 3rd - degree atrioventricular block on long - term outcome in cats is unknown . - pubmed
Clinical findings and long - term outcome of 21 cats with 3rd - degree atrioventricular block were studied retrospectively . - pubmed
Presenting signs included respiratory distress or collapse , but 6 cats had no clinical signs of disease . - pubmed
Eight cats had congestive heart failure ( CHF ) at the time that 3rd - degree atrioventricular block was detected . - pubmed
Heart rates ranged from 80 to 140 beats per minute ( bpm ; median 120 bpm ) with no difference in heart rate between cats with and those without CHF . - pubmed
Eleven of 18 cats that had echocardiograms had structural cardiac disease , and 6 cats had cardiac changes consistent with concurrent systemic disease . - pubmed
One cat had atrioventricular nodal lesions detected on histologic examination . - pubmed
Survival did not differ between cats with or without CHF or between cats with or without structural cardiac disease . - pubmed
Thirteen cats with 3rd - degree atrioventricular block survived & gt ; 1 year after diagnosis , regardless of presenting signs or underlying cardiac disease . - pubmed
Third - degree heart block in cats is often not immediately life threatening . - pubmed
METHODS AND RESULTS : Eighty consecutive patients ( pts ) were treated for paroxysmal episodes of AF by segmental ostial ablation of all pulmonary veins and right atrial isthmus ablation . - pubmed
PURPOSE : To evaluate the effect of cyclosporine 0.05 % ophthalmic emulsion ( Restasis , Allergan , Inc. , Irvine , CA ) on contact lens comfort and reducing dry eye symptoms in patients with contact lens intolerance . - pubmed
METHODS : A 5 - week , randomized , investigator - masked study of 17 patients with self - reported contact lens - related dryness . - pubmed
The overall repair failure rate was 1.6 % ( 2 cases ) , with the failures occurring in patients with grade 3 leaks , including 1 who developed meningitis ; there was no failure of grades 1 and 2 leaks . - pubmed
Cost - utility analysis of different peg - interferon alpha-2b plus ribavirin treatment strategies as initial therapy for naive Chinese patients with chronic hepatitis C. - pubmed
However , no cost - effectiveness data have been published using the clinical data from the peg - interferon alpha-2b and ribavirin in the treatment of patients with hepatitis C in Taiwan . - pubmed
CONCLUSIONS : Peg - interferon alpha-2b plus ribavirin combination for 24 weeks therapy in all genotype patients should reduce the incidence of liver complications , prolong life , improve quality of life and be cost - effective for the initial treatment of chronic hepatitis C. - pubmed
Zingiber officinale Roscoe alone and in combination with alpha - tocopherol protect the kidney against cisplatin - induced acute renal failure . - pubmed
The nephroprotective effects of ethanol extract of Zingiber officinale alone and in combination with vitamin E ( alpha - tocopherol ) were evaluated using cisplatin ( single dose of 10 mg / kg body wt , i.p ) induced acute renal damage in mice . - pubmed
We used the p53 ( R172P ) knock - in mouse , which is unable to induce apoptosis but retains intact cell - cycle arrest and cellular senescence pathways , to show that spontaneous tumorigenesis is potently repressed in Terc -/- p53 ( R172P ) mice . - pubmed
One patient in each group died after extubation , and atelectasia occurred in one patient given methylprednisolone . - pubmed
Outcome after liver re - transplantation in patients with recurrent chronic hepatitis C. - pubmed
The identification of factors associated which improved long - term results may help identify hepatitis C positive patients who benefit from liver retransplantation . - pubmed
Outcome after liver retransplantation for recurrent hepatitis C was analyzed in 18 patients ( group 1 ) and compared with hepatitis C positive patients undergoing liver retransplantation for initial nonfunction ( group 2 , n=11 ) and patients with liver retransplantation for other indications ( group 3 , n=169 ) . - pubmed
Five - year survival after retransplantation in patients with recurrent hepatitis C is similar to that in patients undergoing liver retransplantation for other indications . - pubmed
Comparison of extended - release metformin in combination with a sulfonylurea ( glyburide ) to sulfonylurea monotherapy in adult patients with type 2 diabetes : a multicenter , double - blind , randomized , controlled , phase III study . - pubmed
OBJECTIVE : The purpose for this study was to compare the efficacy and tolerability of extended - release metformin ( MER ) administered with a sulfonylurea ( glyburide ) to sulfonylurea monotherapy in patients with type 2 diabetes . - pubmed
METHODS : This multicenter , double - blind , randomized , controlled study enrolled adult patients with type 2 diabetes who were either drug naive or previously treated with oral diabetic medications and who had not achieved glycemic control . - pubmed
OBJECTIVE : The aim of the study was to evaluate the effectiveness of an intervention that targeted both anxious and aggressive behaviors in children with anxiety disorders and comorbid aggression by parent report . - pubmed
While the use of synthetic agents , especially those targeting molecules , is an attractive and reasonable approach to prevent carcinogenesis , it should be noted that traditional herbs and spices also exist along with their active constituents , which have been demonstrated to disrupt inflammatory signal transduction pathways . - pubmed
Notably , this phytochemical has exhibited a wide range of cancer prevention activities in several rodent models of inflammation - associated carcinogenesis . - pubmed
Intracardiac thrombosis and embolism in patients with cardiac amyloidosis . - pubmed
BACKGROUND : Patients with primary amyloidosis ( AL type ) have a poor prognosis , in part due to frequent cardiac involvement . - pubmed
Effect of vitamins C and E supplementation on peripheral oxidative stress markers and pregnancy rate in women with endometriosis . - pubmed
OBJECTIVE : To determine whether vitamins C and E supplementation lowers oxidative stress marker levels and improves pregnancy rate in women with endometriosis . - pubmed
METHODS : Thirty - four women with endometriosis received a bar containing vitamins C and E ( 343 mg and 84 mg , respectively ) or placebo for 6 months . - pubmed
SUMMARY : Fenofibrate therapy was initiated for a 60 - year old Hispanic man with stage 4 chronic kidney disease ( CKD ) for the treatment of hypertriglyceridemia . - pubmed
probability scale indicated that there was a possible association between fenofibrate and renal dysfunction in this patient . - pubmed
CONCLUSION : A 60 - year - old patient developed renal impairment after receiving fenofibrate for the treatment of hypertriglyceridemia . - pubmed
Observed frequency of OSAS in diabetic patients with DAN varies between 26 % and 30 % . - pubmed
, daytime sleepiness , measured by Epworth Sleepiness Scale , ESS ) in patients with suspected OSAS . - pubmed
We examined 196 patients suspected of sleep apnea ( 52 female , 144 male , mean age 58.7 yrs , mean BMI 30.57 kg / m2 ) . - pubmed
All patients underwent overnight polysomnography and were tested for autonomic neuropathy by a method of measuring heart rate variabilty and heart rate response to the Valsalva maneuver , standing and deep breathing using a computerized data analysis system . - pubmed
Eighty diabetic subjects : 52 DAN- , 28 DAN+ ; 116 subjects without diabetes : 101 without autonomic neuropathy ( AN ) , 15 AN+ . - pubmed
Defining OSAS as AHI>5 / h and ESS - Score>9 , 46 % of the diabetic patients DAN+ were positive , whereas in the DAN- group 61 % met the criteria ( non - diabetic patients without AN 50.5 % ; with AN : 60 % ) . - pubmed
Although the group of diabetic patients with autonomic neuropathy had the lowest percentage of OSAS , statistical analysis showed no significance in comparisons between DAN-/DAN+ or diabetic / non - diabetic . - pubmed
METHODS : Study subjects comprised all consecutive patients with noninfectious posterior uveitis who were treated at the Duke Eye Center from March 2004 to July 2007 , and followed for at least nine months , in whom a fluocinolone acetonide implant was initially inserted , and in whom the implant was replaced , or a second implant was inserted because of recurrent inflammation . - pubmed
Acute hemorrhagic pancreatitis ; study of a patient having disseminated fat necrosis , hypocalcemia , hypopotassemia , uremia , diabetes mellitus , ascites and bilateral hydrothorax . - pubmed
QTL for the thermotolerance effect of heat hardening , knockdown resistance to heat and chill - coma recovery in an intercontinental set of recombinant inbred lines of Drosophila melanogaster . - pubmed
Seroprevalence and potential risk of bovine brucellosis in zerograzing and pastoral dairy systems in Uganda . - pubmed
A total of 723 cattle comprised of 497 animals from the pastoral system and 226 animals from the zerograzing system were tested for antibodies against natural B. - pubmed
The animal - level seroprevalence and within - herd range of brucellosis in cattle in the pastoral system were 34.0 % ( 95 % CI : 29.9 , 38.1 ) and 8.1 - 75.9 % , while for those in the zerograzing system were 3.3 % ( 95 % CI : 0.9 , 5.7 ) and 0 - 9.0 % . - pubmed
Accordingly , the objectives of this study are to analyze a North American cohort of patients with ALD with or without a secondary diagnosis of liver disease to estimate ( i ) the incidence of PD and its predictors , as well as ( ii ) the effect of PD on patient survival . - pubmed
METHODS : We conducted a retrospective review of all patients transplanted for ALD surviving for more than 3 months after transplant . - pubmed
Overall 53 % of patients had co - existing causes of liver dysfunction . - pubmed
In all patients , the risk of AD was 24 % and PD 13 % . - pubmed
DESIGN : Serum proteins were analyzed in 26 biochemically active AIP patients that were classified according to the EPI ( European Porphyria Initiative ) guidelines as follows : ( i ) patients who presented a single acute attack having remained so far free of clinical symptoms ; ( ii ) patients who present recurrent attacks or chronic symptoms associated with exacerbations of AIP . - pubmed
CONCLUSIONS : This first study in humans suggests that the clinical expression AIP is associated with a state of under - nutrition and/or with hepatic inflammation due to the sustained accumulation of heme - precursors . - pubmed
Hypopituitarism in adults seems to be a dynamic condition where new deficiencies can appear years after the initial diagnosis , and careful endocrine follow - up of all hypopituitary patients , including those with IGHD , is warranted . - pubmed
Patients were exposed to a 904 - nm infrared laser ( 50 kHz , 28.4 J / cm(2 ) energy density , 40 % duty cycle , spot size 0.8 cm ) . - pubmed
Loss of photic entrainment at low illuminances in rats with acute photoreceptor degeneration . - pubmed
Respiration - related laryngeal electromyography in children with bilateral vocal fold paralysis . - pubmed
We present 2 case reports to demonstrate the relationship between laryngeal muscle activity and respiration in children with bilateral vocal fold paralysis ( BVFP ) by simultaneous laryngeal electromyography ( EMG ) with recording of chest wall movement and intercostal muscle EMG . - pubmed
Laryngeal EMG should be combined with intercostal muscle EMG in the evaluation of children with significant vocal fold dyfunction of either central or peripheral origin . - pubmed
CONCLUSION : Atypical IM may better reveal the precancerous nature of IM and could be a helpful indicator in the clinical follow up of patients . - pubmed
METHODS : Adult asthmatic patients with suspected AERD who underwent BC with L - ASA were included in the study . - pubmed
After BC , 4 patients had an early asthmatic response , 1 had a dual response , and 2 had isolated late responses . - pubmed
Prevalently reported in children , eosinophilic esophagitis has recently been reported with increased frequency also in adults . - pubmed
PATIENTS AND METHODS : We retrospectively reviewed the histological data of consecutive patients with a diagnosis of esophagitis or reflux disease in the period September 2004 - September 2008 . - pubmed
A Case of Lobar Pneumonia with Bacteraemia Caused by the Haemolytic Streptococcus . - pubmed
OBJECTIVE : Presentation of 8 patients with subependymal giant - cell astrocytomas ( SGCA ) associated with tuberous sclerosis complex ( TSC ) . - pubmed
MATERIAL AND METHODS : There are 8 patients , 6 males and 2 females with TSC , who presented with the tumour between the neonatal period and 24 years . - pubmed
Three of the patients were admitted urgently due to blindness and increased intracranial pressure . - pubmed
Incomplete removal of the tumour has always been bad solution as it resulted in the death of the patient ( in one case ) or further surgery operation in the short term . - pubmed
Only one patient developed the tumour suddenly from pre - existing subependymal nodules from the childhood and they had to be removed at 24 years of age . - pubmed
By contrast , 32 patients with TSC and images of subependymal nodules whose CT or MR progress was followed up for between 10 and 30 years did not develop a tumour . - pubmed
Effect of flavonol glycoside in mulberry ( Morus alba L. ) leaf on glucose metabolism and oxidative stress in liver in diet - induced obese mice . - pubmed
BACKGROUND : Mulberry therapies on type 2 diabetic patients or streptozotocin - induced diabetic rats have been reported to improve fasting blood glucose levels . - pubmed
We investigated the effects of dietary consumption of mulberry - leaf powder and purified quercetin 3 -( 6 - malonylglucoside ) , the quantitatively major flavonol glycoside in mulberry leaves , on glucose and lipid metabolism in high - fat diet - induced obese mice . - pubmed
CONCLUSION : Dietary consumption of Q3MG , the quantitatively major flavonol glycoside in mulberry leaves , improved hyperglycemia in obese mice and reduced oxidative stress in the liver . - pubmed
These results suggest that younger children may require a longer isolation period and that patients with pneumonia may require treatment that is more aggressive than standard therapy for pandemic ( H1N1 ) 2009 virus . - pubmed
Nasopharyngeal carriage rate of Streptococcus pneumoniae in children with sickle cell disease before and after the introduction of heptavalent pneumococcal conjugate vaccine . - pubmed
Children with sickle cell disease ( SCD ) are at high risk of severe infection with Streptococcus pneumoniae ( SP ) . - pubmed
From 2002 , all children aged & lt;5 years in the UK with SCD were recommended 7 - valent pneumococcal conjugate vaccine ( PCV-7 ) in infancy and 23 - valent pneumococcal polysaccharide vaccine boosting , in addition to regular penicillin prophylaxis . - pubmed
The introduction of PCV-7 appears to be associated with a shift in distribution of serotypes carried by children with SCD . - pubmed
In selected patients who have a solitary intracardiac melanoma , surgical resection can provide relief from clinical symptoms and minimize potential cardiac sequelae of the tumor . - pubmed
Herein , we present the case of a 31 - year - old man who had a right atrial metastatic melanoma of unknown primary origin . - pubmed
Accordingly , intratumoral injection of HS - TEX could induce specific antitumor immune response more efficiently than that by tumor - derived exosomes , thus inhibiting tumor growth and prolonging survival of tumor - bearing mice more significantly . - pubmed
BACKGROUND : Because the receptor for parvovirus B19 ( B19V ) is on red blood cells ( RBCs ) , we investigated B19V distribution in blood by in vitro spiking experiments and evaluated viral compartmentalization and persistence in natural infection . - pubmed
In this study we examined the effect of the long - acting opioid antagonist naltrexone on the allodynia - like effect of spinal ischemia in rats . - pubmed
An allodynia - like sensory disturbance , where the animals reacted by vocalization to non - noxious mechanical stimuli in the flank area , was consistently seen during several days after ischemia . - pubmed
There is no doubt that arterial hypertension in dialysis patients as well as in patients without renal disease is deleterious for the cardiovascular system . - pubmed
We report thirty patients of TAO in the age - group of 20 - 50 years were treated with the Ilizarov method . - pubmed
MATERIALS AND METHODS : Patients with severe rest pain ( n=30 ) , absent distal pulsation ( n=30 ) and ulcer ( n=6 ) and/or gangrene of the toes ( n=4 ) , who had failed the conservative pharmacological modalities of treatment were included . - pubmed
RESULTS : Of the 30 cases , 25 patients became pain free while 1 had partial relief of pain . - pubmed
The four patients worsened on treatment and developed frank infection were amputed . - pubmed
There were two cases of osteomyelitis in our series ; both healed after debridement and both patients had good result , with relief of pain . - pubmed
Cancer cells were added to platelet poor plasma from healthy volunteers . - pubmed
The most heat - resistant strain of each of the milk - borne pathogens Staphylococcus aureus , Yersinia enterocolitica , pathogenic Escherichia coli , Cronobacter sakazakii ( formerly known as Enterobacter sakazakii ) , Listeria monocytogenes , and Salmonella was selected to obtain the worst - case scenario in heat inactivation trials using a pilot - plant - scale pasteurizer . - pubmed
Effect of thumb joint mobilization on pressure pain threshold in elderly patients with thumb carpometacarpal osteoarthritis . - pubmed
METHODS : Twenty - eight patients between 70 and 90 years old with secondary TCOA were randomized into glide mobilization and sham groups . - pubmed
METHODS : Twenty - eight patients with pSS treated with rituximab ( 1000 mg ) infusions on days 1 and 15 were included in the study . - pubmed
Five stroke survivors with chronic hemiparesis completed 18 one - hour training sessions over 6 weeks . - pubmed
This is a retrospective single - centre study carried out in patients with a recurrence of an oral cavity or oropharyngeal carcinoma or a second appearance of tumour in a previously irradiated area . - pubmed
METHODS : Between June 2003 and December 2010 , 90 patients with musculoskeletal tumor underwent tumor resection and soft tissue reconstruction . - pubmed
There were 59 males and 31 females with a median age of 37.2 years ( range , 9 - 85 years ) , including 52 bone tumors and 38 soft tissue tumors . - pubmed
Local tumor recurrence was observed in 6 patients , who received second resection at 2 - 27 months ( mean , 8.2 months ) after operation . - pubmed
Mitochondria - addressed cations decelerate the leaf senescence and death in Arabidopsis thaliana and increase the vegetative period and improve crop structure of the wheat Triticum aestivum . - pubmed
Plastoquinone or its methylated form covalently bound to the membrane - penetrating decyltriphenylphosphonium cation ( SkQ1 and SkQ3 ) retarded the senescence of Arabidopsis thaliana rosette leaves and their death . - pubmed
These results indicate that the tested compounds act as antioxidants , that ROS participate in aging and death of A. - pubmed
CONCLUSIONS : The current findings suggest that estrogen - alone use in postmenopausal women results in a modest but sustained reduction in the frequency of joint pain . - pubmed
In vivo human tissue compliance of the normal and cancer gastrointestinal tissue is unknown . - pubmed
The data were used to calibrate the CRTCMS to predict cancerous tissue in a further 12 patients ( 3 cancer esophagus and 9 cancer stomach ) involving 175 measurements . - pubmed
All consecutive patients admitted for workup of neurosyphilis under the Social Hygiene Service , in Hong Kong , were included . - pubmed
Using diagnostic case definition standard stipulated in the IUSTI 2008 guidelines , 17 patients satisfied the diagnosis of neurosyphilis . - pubmed
The most common organisms isolated in early onset and late onset VAP was Pseudomonas aeruginosa , E.coli and Acinetobacter baumanii . - pubmed
PATIENTS OR OTHER PARTICIPANTS : Twenty - five female college athletes ( age = 19.4 + - 1.4 years , height = 170.2 + - 7.4 cm , mass = 67.3 + - 10.0 kg ) with histories of unilateral ankle sprain . - pubmed
OBJECTIVE : Soybean phytoestrogens , such as genistein and daidzein , reduce climacteric symptoms and the risk of certain chronic diseases such as cancer and cardiovascular diseases . - pubmed
CONCLUSIONS : The use of tissue expanders to treat ischial pressure ulcers , especially in patients with long life expectancy , offers important advantages over other approaches . - pubmed
A cross - sectional study was conducted in a university hospital , enrolling 40 patients with pre - eclampsia ( case group ) and 40 healthy normotensive pregnant women ( control group ) . - pubmed
Total antioxidative activity was similar between pre - eclamptic and normotensive patients ( p & gt ; 0.05 ) . - pubmed
ECM components were visualized by Sirius red and immunohistochemistry staining and quantified by western blot analysis in mice with unilateral ureteral obstruction ( UUO ) . - pubmed
METHODS : This randomized clinical trial enrolled patients with chronic wounds between March 2012 and December 2013 . - pubmed
Patients who achieved wound closure were followed up for a minimum of 6 months to evaluate the quality of healing . - pubmed
More patients achieved complete wound closure in the skin cell group than in the control group ( 41 versus 34 patients ; P = 0 035 ) . - pubmed
Aggravation of hepatopulmonary syndrome after sildenafil treatment in a patient with coexisting portopulmonary hypertension . - pubmed
We report a case of a patient who had both HPS and PPHTN at the time of presentation . - pubmed
Boron ( B ) deficiency has seriously negative effect on citrus production . - pubmed
To understand the molecular basis of citrus rootstock to B - deficiency , suppression subtractive hybridization ( SSH ) and microarray approaches were combined to identify the potential important or novel genes responsive to B - deficiency . - pubmed
This case report highlights a rare site of bleeding following LMWH use in a haemodialysis patient . - pubmed
Cured ' mice were also resistant to lymphoma re - challenge 80 days later indicating successful generation of immunological memory . - pubmed
OBJECTIVE : To investigate and analysis the clinical and pathological characteristic of gastrointestinal stromal tumor ( GIST ) patients , and to clarify the factors that effect on prognosis . - pubmed
METHODS : The clinical and pathological features and follow - up of GIST patients who received surgery in Peking Union Medical College Hospital from May 2002 to December 2013 were analyzed retrospectively . - pubmed
RESULTS : A total of 558 GIST patients were collected , including 284 males and 272 females . - pubmed
Patients who took targeted therapy with moderate and high risk of recurrence had a better prognosis compared with not taking the drug . - pubmed
Tumor size , location , mitosis count and tumor rupture are independent prognostic factors of GIST patients . - pubmed
Although the disease is considered on the verge of disappearance even in tropical countries , its real potential for reemergence - due to new strains of Haemophilus ducreyi , underreporting and a lack of widespread use of molecular testing - could be underestimated . - pubmed
PURPOSE : Exercise - induced skeletal muscle deoxygenation is startling by its absence in early post - myocardial infarction ( MI ) patients . - pubmed
We therefore investigated whether aerobic training could enhance the muscle deoxygenation in early post - MI patients . - pubmed
We observed limited GVHD , no TRM , and successful engraftment sufficient to eliminate manifestations of disease in all patients . - pubmed
PATIENTS AND METHODS : In this case - control study , 156 inflammatory bowel disease patients ( 110 ulcerative colitis and 46 Crohn ' s disease patients ) and 131 healthy controls were enrolled . - pubmed
The characteristics of the on- and off - responses in the human diabetic retina by a " long - duration " multifocal electroretinogram ( mfERG ) paradigm were investigated . - pubmed
Twenty type II diabetic patients with no or mild non - proliferative diabetic retinopathy ( NPDR ) and twenty - one age - matched healthy controls were recruited for " long - duration " mfERG measurements . - pubmed
The larger amplitude of the on - response component ( N2 ) in the diabetic patients suggested an imbalance of lateral antagonism , and the lesser percentage change of N2 amplitude in the diabetic group may indicate an impairment of the cross - talk at the middle retinal level in early stages of DM . - pubmed
have made a meaningful contribution to the orthopaedic literature with this study that reports the clinical outcomes of 80 patients who underwent arthroscopic transtendon repair of high - grade , articular - sided partial - thickness rotator cuff tears . - pubmed
Nonalcoholic fatty liver disease diagnosed by transient elastography with controlled attenuation parameter in unselected HIV monoinfected patients . - pubmed
CONCLUSION : NAFLD and significant liver fibrosis diagnosed by transient elastography with CAP are major comorbidities in unselected HIV monoinfected persons on antiretroviral therapy , particularly if metabolic conditions and elevated ALT coexist . - pubmed
The experience with captopril is limited in patients who are hypertensive after renal transplantation . - pubmed
We have used captopril in 58 transplanted patients with hypertension . - pubmed
Captopril in combination with a diuretic and a beta - blocker , reduces blood pressure in patients with treatment resistant hypertension following renal transplantation . - pubmed
OBJECTIVE : To evaluate the performance of low contrast media ( CM ) dose dual - energy computed tomography pulmonary angiography ( CTPA ) with advanced monoenergetic reconstructions in patients with suspected pulmonary embolism ( PE ) . - pubmed
Seven of the 41 ( 17 % ) patients in the low and 5/41 ( 12 % ) in the standard CM dose group were diagnosed with PE ( p = 0.32 ) . - pubmed
No patient suffered from subsequent PE or PE - associated death during the follow - up period . - pubmed
METHODS : Specimen were collected from 202 patients who underwent gastric resection for gastric adenocarcinoma . - pubmed
Perioperative outcomes in human immunodeficiency virus - infected patients - the PRO HIV study . - pubmed
DISCUSSION : RMSF occurs through transmission of Rickettsia rickettsii by an infected tick . - pubmed
Five patients had profound developmental delay and were nonverbal and 4 of them had epilepsy . - pubmed
The perioperative courses were uncomplicated except a 2 year - old girl having an intraoperative bronchospasm , a 16 year - old girl requiring flumazenil administration , and 28 year - old man who was electively intubated with a videolaryngoscope because of airway management concerns . - pubmed
Bacillus cereus is a Gram - positive spore - forming bacterium causing food poisoning and serious opportunistic infections . - pubmed
They were classified into the CMV - induced thrombocytopenia ( 23/29 ) and CMV - related secondary immune thrombocytopenia ( ITP , 6/29 ) groups . - pubmed
IVIG was used for 21 patients , and six patients among them showed recurrence , for whom IVIG or antiviral therapy was used . - pubmed
All , except one , recurrent or chronic cases belonged to the CMV - induced thrombocytopenia group . - pubmed
Antiviral therapy was used more frequently for the CMV - induced thrombocytopenia group ( 8/23 , 34.8 % ) than for the CMV - related secondary ITP group ( 0/6 ) ; however , the results were not statistically significant ( P=0.148 ) . - pubmed
Further , CMV - induced thrombocytopenia is more complex than CMV - related secondary ITP . - pubmed
These patients were at very low risk for MACE ( 0.4 % in 30 - days and 2.3 % in one - year ) . - pubmed
We studied antidiabetic effects and cytoprotective activity of two lithium salts ( lithium chloride and lithium carbonate ) on the model of streptozotocin - induced diabetes mellitus type 2 in Wistar rats . - pubmed
Both lithium preparations administered to diabetic animals for 28 days in doses of 10 and 8.9 mg / kg , respectively , attenuated the damaging effect of streptozotocin . - pubmed
Exposure to cigarette smoke via respiratory system may induce abnormal alterations of reproductive organs in female diabetic rats . - pubmed
Long - Term Effects of Early Life Seizures on Endogenous Local Network Activity of the Mouse Neocortex . - pubmed
Conclusion : Inappropriate doses of antibiotics , a diagnosis of septic shock and the presence of at least two comorbidities were found to significantly increase the mortality rate of sepsis patients admitted to an ICU in Indonesia . - pubmed
Indeed , several PG species were associated with the severity of obesity in mice and humans . - pubmed
Maternal dyslipidemia during pregnancy and lactation increases blood pressure and disrupts cardiorespiratory and glucose hemostasis in female rat offspring . - pubmed
In urine samples from men who have sex with men ( n = 400 ) attending a sexually transmitted disease clinic in Dublin , the prevalence of M. - pubmed
Efficacy of Sugammadex in Preventing Skin Test Reaction in a Patient With Confirmed Rocuronium Anaphylaxis : A Case Report . - pubmed
Matching - Adjusted Indirect Comparison of Blinatumomab vs. Inotuzumab Ozogamicin for Adults with Relapsed / Refractory Acute Lymphoblastic Leukemia . - pubmed
INTRODUCTION : In the absence of head - to - head trials , this analysis aimed to provide a fair indirect comparison of the efficacy between blinatumomab and inotuzumab ozogamicin ( InO ) , two treatments for adult patients with relapsed or refractory acute lymphoblastic leukemia ( R / R ALL ) who received no more than one prior salvage therapy , by adjusting for cross - trial differences . - pubmed
Patients with 2 + prior salvage therapies from TOWER were excluded because such patients were not included in INO - VATE - ALL . - pubmed
The patient discussed in this case presented with hoarseness and dysphagia after receiving epidural anesthesia for childbirth . - pubmed
The proposed mechanism for this patient , and in others described in the literature , is puncture of the dura with subsequent egress of cerebrospinal fluid , leading to intracranial hypotension and traction on cranial nerves . - pubmed
Unilateral vocal fold paralysis following spinal anesthesia has been reported in one case series consisting of three patients , but this represents the first case of bilateral paralysis . - pubmed
Patients presenting with idiopathic vocal fold paralysis , in summary , should be questioned about recent history of epidural or spinal anesthesia , as a positive history may point to transient intrathecal hypotension as a potential etiology of the paralysis . - pubmed
Chelonid Alphaherpesvirus 5 DNA in Fibropapillomatosis - Affected Chelonia mydas . - pubmed
Fibropapillomatosis is a panzootic and chronic disease among Chelonia mydas - usually associated with anthropogenic impacts . - pubmed
This study contributes towards understanding fibropapillomatosis implications for C. - pubmed
Patients were included if they had bipolar cartilage lesions of the knee treated surgically . - pubmed
Whole - Genome Sequencing to Differentiate Relapse From Reinfection in Community - Onset Bacteremic Acinetobacter baumannii Pneumonia . - pubmed
Community - onset bacteremic Acinetobacter baumannii pneumonia recurred in 3 of 30 ( 10 % ) patients followed prospectively , all with ongoing hazardous alcohol intake , 3 - 56 months after initial pneumonia . - pubmed
Dupilumab improves health - related quality of life in patients with chronic rhinosinusitis with nasal polyposis . - pubmed
In a previously reported randomized clinical trial ( NCT01920893 ) , addition of dupilumab to mometasone furoate in patients with CRSwNP refractory to intranasal corticosteroids ( INCS ) significantly improved endoscopic , radiographic , and clinical endpoints and patient - reported outcomes . - pubmed
RESULTS : Following 16 weeks of treatment , the proportion of patients with moderate - to - severe CRSwNP ( VAS & gt;3 - 10 ) decreased from 86.2 % to 21.4 % with dupilumab and 88.0 % to 84.2 % with placebo . - pubmed
CONCLUSIONS : In adults with CRSwNP refractory to treatment with INCS alone , the addition of dupilumab reduced disease severity , significantly improved HRQoL , and improved productivity . - pubmed
Bone marrow aspirates form patients with multiple myeloma were obtained and lymphocytes were isolated using density gradient centrifugation . - pubmed
CONCLUSION : Magnetic stents cause similar morbidity for patients compared with standard stents removed by flexible cystoscopy ; they are associated with less pain at removal and are cost saving . - pubmed
In order to examine the efficacy of human cell based therapy in anthracycline - induced injury , we characterized a mouse model using an immune compromised strain of mice capable of accepting human cells . - pubmed
Gastrointestinal and hepatic injury occurred at 4 mg / kg and 1.5 mg / kg dosing while mice receiving 0.5 mg / kg weekly only displayed hepatic damage . - pubmed
Histological assessment shows no overt cardiomyocyte injury but livers from mice treated with doxorubicin show marked hepatic plate atrophy with intracytoplasmic and canalicular cholestasis , rare pericentral hepatocellular necrosis and significant zone 3 iron accumulation , likely an indication of metabolic injury due to doxorubicin toxicity . - pubmed
Conclusions : Immune compromised mice are sensitive to doxorubicin therapy resulting in systemic complications in addition to cardiovascular toxicity . - pubmed
Anthracycline - induced cardiotoxicity is observed at very low doses in NOD.Cg - Prkdcscid Il2rgtm1Wjl / SzJ mice . - pubmed
Ultimately , the management of advanced BTC is likely to become molecularly selected in the near future with the hope of finally improving the bleak prognosis of patients with this disease . - pubmed
A second generation of anti - complement agents is currently under investigation , representing future promising therapeutic strategies for patients affected by PNH . - pubmed
edodes stress - sensitive strain YS55 via the Agrobacterium - mediated transformation method . - pubmed
METHODS : A total of 2,199 MS patients ( female / male ratio of 1,651/548 ) underwent structural MRI imaging on either a 1.5 - T or 3 - T scanner . - pubmed
This study aimed to investigate the changes in anxiety , depression , the ratios of T helper cells 17 ( Th17 ) and regulatory T cells ( Tregs ) , and inflammation levels in patients with pulmonary nodules . - pubmed
The patients were divided into two groups according to the scale scores : 62 cases in a non - anxiety and non - depression ( NAD ) group and 41 cases in an anxiety and/or depression ( AD ) group . - pubmed
The proportion of anxiety and/or depression in female patients with pulmonary nodules was higher than that in males ( P<0.05 ) . - pubmed
CONCLUSIONS : Patients with pulmonary nodules are prone to varying degrees of anxiety and depression , which leads to immune dysfunction and low - grade inflammation . - pubmed
BACKGROUND : Coronaviruses ( CoVs ) were long thought to only cause mild respiratory and gastrointestinal symptoms in humans but outbreaks of Middle East Respiratory Syndrome ( MERS )- CoV , Severe Acute Respiratory Syndrome ( SARS )- CoV-1 , and the recently identified SARS - CoV-2 have cemented their zoonotic potential and their capacity to cause serious morbidity and mortality , with case fatality rates ranging from 4 to 35 % . - pubmed
However , we did observe a protective effect in an organotypic respiratory cell culture system by exposing pre - treated respiratory epithelium to droplets of HCoV-229E , imitating a natural infection . - pubmed
The observed virucidal activity of Echinaforce was not restricted to common cold coronaviruses , as both SARS - CoV-1 and MERS - CoVs were inactivated at comparable concentrations . - pubmed
OBJECTIVE : To evaluate sleep disorders and chronotype in patients with drug resistant focal and generalised epilepsy compared to healthy controls . - pubmed
METHODS : Sixty four patients with focal and six with generalised , drug resistant epilepsy were included and compared to 70 age- and gender - matched healthy controls . - pubmed
The impact of epilepsy on quality of life was also documented in patients . - pubmed
Self - reported confusional arousals and probable REM sleep behaviour disorder ( RBD ) were more frequent in patients ( 30.4 % vs. 8.6 % , p = 0.036 and 10.6 % vs. 1.4 % , p = 0.030 , respectively ) . - pubmed
A higher risk for possible sleep apnea was identified in patients ( 22.9 % vs. 5.7 % , p = 0.042 ) , whereas Epworth Sleepiness Score was normal in both groups ( p = 1 ) . - pubmed
CONCLUSION : Self - reported confusional arousals , probable RBD and a high risk for sleep apnea occurred significantly more often in patients with drug resistant epilepsy . - pubmed
MOTIVATION : Beside socio - economic issues , coronavirus pandemic COVID-19 , the infectious disease caused by the newly discovered coronavirus SARS - CoV-2 , has caused a deep impact in the scientific community , that has considerably increased its effort to discover the infection strategies of the new virus . - pubmed
Despite the lack of shared human proteins in these virus - host networks , and the low number of preserved virus - host interactions , the consensus alignment revealed aligned human proteins that share a function related to viral infection , as well as human proteins of high functional similarity that interact with SARS - CoV-1 and SARS - CoV-2 proteins , whose alignment would preserve these virus - host interactions . - pubmed
We are witnessing an unparalleled pandemic caused by the novel Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS - CoV-2 ) associated with coronavirus disease 2019 ( COVID-19 ) . - pubmed
Thus , we characterize the AT- and CG - rich DNA pattern for the genus Rhodnius , and we suggest that the pattern of CG - rich heterochromatin in the autosomes of these vectors evolved independently in pallescens , pictipes , and prolixus groups . - pubmed
Potential effect of tropical fruits Phyllanthus emblica L. for the prevention and management of type 2 diabetic complications : a systematic review of recent advances . - pubmed
Taken together , Phyllanthus emblica may be an ideal fruit for controlling diabetic complications . - pubmed
This review highlights the latest findings of the role of Phyllanthus emblica in anti - diabetes and its complications , especially clarifies the molecular mechanism of the chemical components related to this effect , and prospects some existing problems and future research directions . - pubmed
Objective : Patients with cancer pain are highly dependent on morphine analgesia , but studies have shown a negative correlation between morphine demand and patient outcomes . - pubmed
Finally , the LLC murine lung adenocarcinoma cell line were used to establish a murine lung cancer model , and the effects of M3 G on tumor growth and metastasis were determined . - pubmed
Cellular energy metabolism , trans - plasma and trans - mitochondrial membrane potentials , and pH gradients in mouse neuroblastoma . - pubmed
coli enterotoxin released from a porcine E. coli strain into culture medium . - pubmed
The hematopoiesis of athymic - asplenic ( lasat ) mice was compared with that of normal , asplenic , and athymic littermates with the same strain background . - pubmed
Erythrocyte blood volume , number and survival time were normal when related to the body weight of the animals . - pubmed
When diabetic subjects with triglyceride levels over 400 mg / dl were selected for study , most were found to have an independent familial form of hypertriglyceridemia . - pubmed
In a group of 156 patients with arteriopathy , 87 ( aged between 10 and 40 years ) exhibited thromboangiitis obliterans and 9 ( aged 40 to 50 years ) arteritis of middle age , according to Van der Stricht 's classification . - pubmed
Chemotherapy of a human malignant melanoma transplanted in the nude mouse . - pubmed
The effects of single agent therapy with 1 -(- chloroethyl )- 3 - cyclohexyl-1 - nitrosourea , 5 - fluorouracil , and 5 -( 3,3 - dimethyl-1 - triazeno )- imidazole-4 - carboxamide on a human malignant melanoma transplanted and passed serially in thymusless nude mouse were studied . - pubmed
The results resemble those reported from clinical practice in patients with disseminated malignant melanomas treated with the same agents . - pubmed
This suggests that the pattern of drug susceptibility is preserved after transplantation of tumors in the nude mouse . - pubmed
The human tumor - nude mouse system is advocated as a new in vivo model for determination of individual tumor response to chemotherapeutic agents , and its potential as a model for the proving of new chemotherapeutic agents is suggested . - pubmed
Detection of papillomaviral - like DNA sequences in premalignant and malignant perineal lesions of sheep . - pubmed
Small hyperkeratotic and ulcerated lesions and clinical cancers were isolated from the perineal region of sheep and examined for evidence of papillomavirus infection by various criteria including gross morphology , histology , immunohistochemistry and DNA hybridisation . - pubmed
This finding suggests that a papillomavirus is associated with the development of squamous cell carcinomas of the perineum of sheep . - pubmed
Angioplasty in the patient with an evolving myocardial infarction : with and without surgical backup . - pubmed
Tuberculosis could have been diagnosed without mediastinoscopy only in 3 patients : 2 had positive bronchial cultures and 1 simultaneous cervical lymph node tuberculosis . - pubmed
An outbreak of human and canine blastomycosis . - pubmed
In the summer and fall of 1988 , three humans and one dog in a lakeshore community in northern Wisconsin were found to have blastomycosis on the basis of the results of cultures and histologic studies ; the infection was also suspected in one human and four dogs on the basis of clinical data . - pubmed
The result of this study further confirm the common occurrence of self - limited and subclinical infection with B. dermatitidis and suggest that excavation in an area endemic for B. - pubmed
dermatitidis is a risk factor for human and canine infection . - pubmed
Development of EEG background activity in children with benign partial epilepsy . - pubmed
We investigated the developmental features of the EEG - background activity of the 30 patients with benign childhood epilepsy . - pubmed
In the patients with benign childhood epilepsy , the development of the EEG - background activity came to be stagnant from 6 years old or so , and after 10 years old it developed again and approached to that of the normal children . - pubmed
It is suspected that the EEG background activity of children with benign partial epilepsy shows a special development . - pubmed
The excitatory amino acid antagonists GDEE and MK-801 [ ( + ) - 5 - methyl-10,11 - dihydro-5H - dibenzo [ a , d ] cyclo - hepten-5,10 imine ] were tested as anticonvulsants for strychnine - induced seizures in 3AP inferior olive - lesioned and control rats . - pubmed
Neither drug effected seizures in control rats , however , both GDEE and MK-801 produced a leftward shift in the strychnine - seizure dose - response curve in 3AP inferior olive - lesioned rats . - pubmed
The frequency of bilateral physiolysis colli femoris was evaluated in 62 patients . - pubmed
We recommend bilateral pinning at first admission in all patients with a slipped capital femoral epiphysis . - pubmed
Mediastinal lymph node dissection in bronchial carcinoma patients means an additional procedure to the tumor resection . - pubmed
In this report the authors describe a patient who developed anterior wall myocardial infarction secondary to a blunt chest trauma . - pubmed
The ocular examinations and hospital records of 64 patients with Hollenhorst plaques were retrospectively reviewed to document any associated visual defects and to determine if carotid endarterectomy prevented the occurrence of new plaques or symptoms . - pubmed
Twenty - eight carotid endarterectomies were performed ipsilateral to a Hollenhorst plaque : 24 patients had no symptoms ; four patients developed new ipsilateral asymptomatic Hollenhorst plaques at 1 to 50 months after operation . - pubmed
Eight eyes in patients with no symptoms had multiple Hollenhorst plaques , one of which was associated with a subsequent stroke . - pubmed
An analysis of factors associated with ectopic pregnancy in a human in vitro fertilization program . - pubmed
Antiulcerogenic activities of three plant drugs were studied against aspirin - induced gastric ulcers in rats . - pubmed
Solanum nigrum ( aerial parts ) powder and its methanolic extract decreased the ulcer index significantly . - pubmed
Brassica oleracea ( leaf ) powder did not affect the ulcer index significantly but its aqueous extract lowered the index and increased hexosamine levels , suggesting gastric mucosal protection . - pubmed
A middle - aged woman presenting with multiple cranial neuropathies , hemiparesis , and CSF pleocytosis had tuberculous infection of the cranial dura mater at autopsy . - pubmed
Valpromide increases the plasma concentrations of amitriptyline and its metabolite nortriptyline in depressive patients . - pubmed
The effects of valpromide on amitriptyline ( AMT ) and nortriptyline ( NT ) plasma levels were examined in 20 depressed inpatients . - pubmed
[ Is cataract surgery with posterior chamber lens in patients with senile maculopathy worthwhile ? ] - pubmed
To determine if PVAs initiated in patients with spontaneous sustained ventricular tachycardia or fibrillation differ from those which are clearly a nonspecific response in structurally normal hearts , the initiation , characteristics , and relationship to ventricular repolarization of PVAs greater than five beats in duration were evaluated in 32 patients without structural heart disease and in 36 patients with spontaneous sustained ventricular arrhythmias more than 9 days after myocardial infarction . - pubmed
In a comparison with patients who completed the same steps ( defined by the basic drive cycle length and number of extrastimuli ) in the stimulation protocol , there was no difference in the cumulative risk of initiation of a PVA between the patients with and those without heart disease at any step . - pubmed
The morphology of the apical surface of rabbit retinal pigment epithelium was studied by scanning electron microscopy from the first minute to several hours after making small nonrhegmatogenous retinal detachments ( blebs ) . - pubmed
[ Immunomorphological changes in the tumors and regional lymph nodes in breast cancer patients treated preoperatively with radioactive gold ] . - pubmed
Aspergillus fumigatus infection in the scaly weaver ( Sporopipes squamifrons ) . - pubmed
Morphometry of right ventricular hypertrophy induced by myocardial infarction in the rat . - pubmed
The growth response of the right ventricle was studied in rats following ligation of the left coronary artery , which produced infarcts comprising approximately 40 % of the left ventricle . - pubmed
[ Plasma catecholamine changes in patients with acute myocardial infarction and their clinical significance ] . - pubmed
Angiotensin II infusions did not increase plasma catechol - amines , and lowering of angiotensin II by captopril treatment in patients with severe hypertension or congestive heart failure failed to alter plasma adrenaline or nor - adrenaline levels . - pubmed
High - dose Ara - C for remission induction and consolidation of previously untreated adults with ALL or lymphoblastic lymphoma . - pubmed
Thirty - two patients with untreated ALL ( n = 26 ) or lymphoblastic lymphoma ( n = 6 ) between 17 and 65 years of age were treated with a short remission induction course with VP16 - 213 , amsacrine , intermediate dose Ara - C for 6 days , prednisone and intrathecal methotrexate , followed by a consolidation course with vincristine , amsacrine , high dose Ara - C for 4 days , prednisone and intrathecal methotrexate . - pubmed
Ten of 13 patients with T - ALL or lymphoma , six of eight patients with pre - B or common ALL , and seven of 11 patients with B - ALL or Burkitt ' s lymphoma achieved a complete remission . - pubmed
Long - term survival for patients with B or T - ALL was approximately 60 % , compared with 15 % for those with common or pre B - ALL . - pubmed
Our regimen may be sufficient for patients with T or B - ALL . - pubmed
[ The clinical picture , diagnosis and rationale for the combined treatment of patients with an intracranial hypertension syndrome of nontumor origin . - pubmed
To evaluate the effect of hyperbaric oxygen therapy on chronic wound healing , 16 otherwise healthy patients who had nondiabetic , chronic leg ulcers with no large vessel disease were included in a double - blind study . - pubmed
The wound area was copied onto transparent film covering the wound and then measured using only one matching wound from each patient . - pubmed
Monkey cerebral arterial relaxation caused by hypercapnic acidosis and hypertonic bicarbonate . - pubmed
Stomach function and secretions are altered significantly in patients with cirrhosis , both with or without portal hypertension . - pubmed
In order to correlate morphologic parameters and functional assessment , a prospective study was performed on 45 patients after surgical treatment of intraarticular calcaneal fractures using standard radiographic and computed tomographic scores , clinical evaluation , and gait analysis ( dynamic pedography ) . - pubmed
The detection and typing analysis of human papillomavirus ( HPV ) were carried out by means of BIOHIT in situ HPV DNA hybridization screening and typing kits in condyloma tissues of patients with genital condyloma acuminatum , in cytological smears of their asymptomatic female consorts , and in female patients with vulval condyloma acuminatum . " - pubmed
Low"-risk HPV 6 and HPV 11 were demonstrated most frequently in the condyloma tissues of the male patients . - pubmed
Medium " and " high"-risk HPV 18 , 31 and 33 types ( frequently associated with high - grade dysplastic lesions and carcinomas ) were demonstrated more frequently in female condylomas than in male . - pubmed
These three HPV types were identified in both tissues in a female patient with condyloma acuminatum and carcinoma epidermoids cornescens . - pubmed
Twelve patients demonstrated a vasospasm on 22 angiographies . - pubmed
There were no survivors among an estimated 398 patients who had lung injury and either required more than 4 hours of vasopressor support or had sustained hepatic and renal failure . - pubmed
Through the use of these factors , an accurate prediction of death could have been made in the first 4 days of mechanical ventilation for more than half of the patients who did not survive . - pubmed
CONCLUSION : Of the patients who required mechanical ventilation after bone marrow transplantation , no one survived with lung injury combined with either hemodynamic instability or hepatic and renal failure . - pubmed
Some of the most important clinical applications involve the early detection of iris new vessels , cataract management in diabetic patients , and monitoring of iris tumors . - pubmed
SCH 47112 , a novel staurosporine derivative , inhibits 12 - O - tetradecanoylphorbol-13 - acetate - induced inflammation and epidermal hyperplasia in hairless mouse skin . - pubmed
METHODS : We observed the microcirculation in nailfold of 30 normal pregnant women and 76 cases of PIH . - pubmed
It has been shown previously that tobramycin encapsulated in fluid liposomes ( composed of dipalmitoylphosphatidylcholine ( DPPC ) and dimyristoylphosphatidylglycerol ( DMPG ) ) eradicated mucoid Pseudomonas aeruginosa in an animal model of chronic pulmonary infection . - pubmed
Six hours and 16 h after treatment , the maximal reduction of growth between strains treated with liposome - encapsulated tobramycin and free tobramycin was 84 , 129 , 166 , 10(5 ) and 10(4 ) times respectively for P. - pubmed
OBJECTIVE : To review our experience of surgical staging for residual masses after chemotherapy in patients with nonseminomatous germ cell tumour ( NSGCT ) and positive tumour markers . - pubmed
PATIENTS AND METHODS : Of 107 patients with metastatic NSGCTs treated surgically after chemotherapy from 1978 to 1995 , 30 ( median age 30.5 years , range 20 - 52 ) had positive tumour markers . - pubmed
These patients were reviewed and the outcome compared with 77 patients who had normal tumour marker values . - pubmed
RESULTS : Of the 77 patients with negative markers undergoing surgical / pathological staging , 71 ( 92 % ) became continuously disease - free , including 37 of 50 ( 74 % ) with viable NSGCT in excised specimens . - pubmed
CONCLUSION : Although the outcome after surgery is better in patients with negative tumour markers , it is clear that surgery is curative for patients with localized chemotherapy - resistant masses . - pubmed
Thus , in frail elderly patients , there are contradictory relationships between DHEA - S and neuropsychiatric measures of frailty ( cognitive impairment , disability , insomnia , and number of pain sites ) , and there may also be gender differences in these relationships . - pubmed
Liver transplantation for endstage hepatitis C cirrhosis in a patient with primary hypogammaglobulinaemia . - pubmed
Liver transplantation was performed in a patient with primary hypogammaglobulinaemia , chronic hepatitis C and hepatic failure . - pubmed
Liver biopsies demonstrated the recurrence of HCV . - pubmed
14 months after the transplantation the patient developed severe diarrhoea caused by Cryptosporidium parvum . - pubmed
The present case report illustrates the difficulties associated with organ transplantation in patients with primary hypogammaglobulinaemia . - pubmed
Early dialysis in heart insufficiency of patients with chronic renal failure . - pubmed
In patients with severe heart failure life expectancy is short , the quality of life is affected , and the service costs are very high . - pubmed
In our study we followed patients suffering from class - IV cardiac failure concomitant with chronic renal failure . - pubmed
Here we describe a case of gastrointestinal autonomic nerve tumor ( GANT ) arosen in a patient with von Recklinghausen ' s disease . - pubmed
Prevalence of verotoxin - producing Escherichia coli ( VTEC ) in bovine coli mastitis and their antibiotic resistance patterns . - pubmed
Between December 1996 and October 1997 , milk samples from a total of 145 cows with coli mastitis were screened for the presence of verotoxin - producing E. - pubmed
The four isolated strains proved to be verotoxin ( VT ) 1- , VT2- or VT1- and VT2 - positive . - pubmed
OBJECTIVE : This is a report of endovascular treatment of a case of type B thoracoabdominal aortic dissection in a patient with progressive dyspnea , dorsolumbar pain , and expanding aortic diameter over a 1 - year period . - pubmed
The camptothecin derivatives topotecan and irinotecan represent new weapons in our arsenal for battling human cancer . - pubmed
The endothelium of spontaneously hypertensive rats ( SHR ) released 35 % less NO ( 580 + /- 30 nmol l(-1 ) ) than that of normotensive rats ( 920 + /- 50 nmol l(-1 ) ) , due to the higher production of O2- in SHR rats . - pubmed
Ischemia ( lower limb of rabbit ) caused a significant increase of NO peaking at 15 min and decreasing thereafter , also due to O2- production . - pubmed
A girl with a history of insulin - dependent diabetes mellitus since 5.5 years , and Hashimoto ' s thyroiditis since 12 years , developed episodes of severe hypoglycemia from the age of 12 years . - pubmed
Effect of phenobarbitone administration to pregnant rats on anxiety in offsprings . - pubmed
The unusual site of infection may probably be related to the use of contaminated needless and syringes for HIV drug injection . - pubmed
METHODS : Five patients with gastric GIST ( 36 - 85 years old ) underwent subserosal excision with subsequent B - II resection ( 1x ) , full - thickness partial gastric resection ( 2x ) , gastrotomy with submucosal excision ( 1x ) , or gastrectomy for carcinoma with an incidental finding of a leiomyoma ( 1x ) . - pubmed
To date , fluorouracil plus folinic acid represents the standard therapy in CRC for the adjuvant treatment of patients at high risk for relapse and for the first - line treatment of metastatic disease . - pubmed
Future research is focused on enabling clinicians to individualise treatment strategies in patients with CRC , so as to improve clinical outcomes and reduce drug toxicity . - pubmed
Mortality among patients with breast cancer ( BC ) is mainly caused by metastasis . - pubmed
We distinguished the mRNA levels in circulation between BC patients and healthy controls with reference to a BC - derived cell line , SK - BR-3 . - pubmed
We prospectively analyzed peripheral blood samples from 33 BC patients and 26 healthy controls . - pubmed
OBJECTIVE : The objective of the study was to study gall bladder volume in fasting and 45 minutes post - prandial , by real time ultrasound in healthy controls and diabetic patients with and without autonomic neuropathy and to compare them . - pubmed
METHOD : Age , Sex and body mass index ( BMI ) matched 50 healthy subjects and 10 patients with insulin dependent diabetes mellitus and 40 patients with noninsulin dependent diabetes mellitus were evaluated according to National diabetes Data Group of National Institute of Health ( 1979 ) criteria : 1 . - pubmed
Patients of diabetes mellitus had statistically significant larger fasting gall bladder volumes and these values were highly significant amongst patients with autonomic neuropathy . - pubmed
CONCLUSIONS : We therefore conclude that impaired gall bladder contraction was found amongst patients of diabetes mellitus with autonomic neuropathy . - pubmed
Vascular invasion in squamous cell carcinomas of human oral mucosa . - pubmed
The process of vascular invasion of human oral squamous cell carcinomas was histologically and immunohistochemically studied in surgical and autopsy specimens . - pubmed
These findings showed that mechanical pressure has an important role in the vascular invasion of human oral squamous cell carcinoma . - pubmed
After 20 months , a group of HFS rats were switched to the LFCC diet ( HFS / LFCC ) for a period of 2 months . - pubmed
In acute LMCA obstruction , lead aVR ST segment elevation also contributes to predicting a patient 's clinical outcome . - pubmed
Cell - mediated immunity to tumors induced by Ab2 was investigated by a delayed - type hypersensitivity response and the mouse T - cell proliferation assay . - pubmed
The glycoprotein was purified from normal plasma and individual chronic myeloid leukemia ( CML ) patients ' plasma by low - pressure chromatography . - pubmed
At 1 year of age , HCII - deficient animals were grossly indistinguishable from their wild - type littermates in weight and survival , and they did not appear to have spontaneous thrombosis or other morphologic abnormalities . - pubmed
In comparison with wild - type animals , however , they demonstrated a significantly shorter time to thrombotic occlusion of the carotid artery after photochemically induced endothelial cell injury . - pubmed
SUBJECTS : Three hundred seventy - four chronic pain patients ( 300 aged 13 to 59 years ; 74 aged 60 to 89 years ) assessed at an outpatient , multidisciplinary pain management centre . - pubmed
METHODS : Patients completed measures of demographic and descriptive information , pain intensity ( box rating scale ) , perceived disability ( modified Pain Disability Index ) and affective distress ( Symptom Checklist-90 Revised ) before multidisciplinary treatment . - pubmed
We present the case of a 16 - day - old infant with tinea capitis caused by Microsporum canis and effectively treated with topical bifonazole 1 % . - pubmed
PURPOSE : We have simplified the treatment of gestational trophoblastic disease ( GTD ) in order to reduce the number of patients exposed to potentially carcinogenic chemotherapy . - pubmed
PATIENTS AND METHODS : Between 1992 and 2000 , 485 women with GTD were commenced on MTX / FA at Charing Cross Hospital , London , United Kingdom . - pubmed
In the present study , we evaluated the speed of cognitive processing in patients with PD without bradykinesia as a variable . - pubmed
This case report presents a patient who developed a large overhanging bleb following antimetabolite trabeculectomy surgery 6 years prior . - pubmed
Adjuvant intraperitoneal chemotherapy with cisplatinum , mitoxantrone , 5 - fluorouracil , and calcium folinate in patients with gastric cancer : a phase II study . - pubmed
Clinical studies have revealed that approximately two thirds of the patients seek treatment for early recurrence within the abdominal cavity . - pubmed
The aim of this phase II study was to evaluate the toxicity , feasibility , and efficacy of adjuvant intraperitoneal chemotherapy ( IPCT ) with cisplatin , mitoxantrone , 5 - fluorouracil ( 5 - FU ) , and folinic acid in patients with stage II - III gastric cancer . - pubmed
The major nonhematologic toxicity from IPCT was grade I - III nausea and/or vomiting experienced by 27 patients ( 69.2 % ) . - pubmed
Twenty - four ( 61.5 % ) patients reported abdominal discomfort . - pubmed
Its association with the infection caused by a virus of the Epstein - Barr family , human herpesvirus 8 ( HHV-8 ) , has been recently demonstrated . - pubmed
In this article we discuss the unusual presentation of a solitary manifestation of Kaposi ' s sarcoma on the penis of a 53 - year - old HIV - negative patient . - pubmed
The case is interesting for its unusual site of presentation , the young age of onset , the association with HHV-8 infection , the HIV - negative serology , and the benign course of the disease . - pubmed
[ Effect of hyperthermia on the red - cell immune function of rats and its teratogenicity on developing embryos ] . - pubmed
Glucose utilization and lactate production by leucocytes of patients with diabetes mellitus . - pubmed
[ Psychoses and psychotic states in children ] . - pubmed
The toxicity of the natural insecticide spinosad was assessed against Daphnia pulex ( Leydig ) using a demographic approach . - pubmed
Theanine , a naturally occurring non - proteinic amino acid found in tea leaves , has demonstrated wide - ranging physiological activity , from lowering blood pressure to enhancing the anti - tumor activity of chemotherapeutic drugs . - pubmed
Naamine G ( 3 ) exhibited strong antifungal activity against the phytopathogenic fungus Cladosporium herbarum and also showed mild cytotoxicity against mouse lymphoma ( L5178Y ) and human cervix carcinoma ( HeLa ) cell lines . - pubmed
Rabies cell culture vaccines reconstituted and stored at 4 degrees C for 1 year prior to use protect mice against rabies virus . - pubmed
Sheep and suckling mouse brain rabies vaccines used in developing countries are being replaced by expensive inactivated - virus cell culture vaccines . - pubmed
Our laboratory has performed studies among pregnant rat and sheep in which we simulate drought conditions via maternal dehydration and famine conditions via nutrient restriction . - pubmed
For the first time , a live genetically modified bacterial strain has been approved by Dutch authorities as a therapeutic agent for experimental therapy of intestinal bowel disease ( IBD ) in humans . - pubmed
OBJECTIVE : The authors evaluated concordance rates among three electrophysiological measures in patients with schizophrenia , nonschizophrenic first - degree relatives of schizophrenia patients , and healthy comparison subjects . - pubmed
Data for all three paradigms were available for 81 patients with schizophrenia , 25 parents of patients with schizophrenia , and 60 healthy comparison subjects . - pubmed
Mechanisms of human diseases have been elucidated along with the progress of the Human Genome Project , which has enabled accurate genetic testing towards personalized medicine . - pubmed
METHODS : A series of 71 females who had undergone transanal repair of low isolated rectocele was retrospectively reviewed . - pubmed
RESULTS : Twenty - nine of 71 patients had isolated low rectocele recurrence , and 6 had a rectocele recurrence associated to an enterocele occurrence . - pubmed
Mounting evidence exists that the activation of proto - oncogene by somatic mutation plays an important roles in the development of human cancers . - pubmed
However , only marginal anti - tumor efficacy of the adenoviral Sant7 was observed . - pubmed
Enterovirus 71 ( EV71 ) is a highly infectious major causative agent of hand , foot , and mouth disease ( HFMD ) which could lead to severe neurological complications . - pubmed
PATIENTS AND METHODS : Thirty - five patients , with histologically verified CIS of the urinary bladder , were included in the study . - pubmed
This has been driven by the purportedly beneficial effects of co - infection on clinical pathology and the recognition of Plasmodium vivax as a public health problem in its own right . - pubmed
Somatic pain sensitivity during formation and healing of acetic acid - induced gastric ulcers in conscious rats . - pubmed
BACKGROUND AND PURPOSE : To investigate the feasibility and potential benefits of combining electron and photon intensity modulated radiotherapy ( IMRT ) for patients with malignant pleural mesothelioma ( MPM ) . - pubmed
CONCLUSIONS : This study showed that IMRT or IMRT+e is a viable treatment modality for MPM patients . - pubmed
The possible implications of these findings for menopausal hormone therapy in women and breast cancer risk are discussed . - pubmed
Operant conditioning of H - reflex can correct a locomotor abnormality after spinal cord injury in rats . - pubmed
These results suggest that appropriately selected reflex conditioning protocols might improve function in people with partial spinal cord injuries . - pubmed
The absence of intervening sequences in 23S rRNA genes of Campylobacter coli isolates from Turkeys is a unique attribute of a cluster of related strains which also lack resistance to erythromycin . - pubmed
In this study , 104 strains of Campylobacter coli from turkeys , representing 27 different multilocus sequence typing - based sequence types ( STs ) , were characterized in terms of IVS content and erythromycin susceptibility . - pubmed
The STs of the latter strains belonged to an unusual cluster of C. - pubmed
coli from turkeys is characteristic of a unique clonal group of erythromycin - susceptible strains and that IVS can be acquired by these strains via natural transformation to erythromycin resistance . - pubmed
We combined analysis of mutations causing human Mendelian diseases , of human - chimpanzee divergence , and of systematic data on human genetic variation and found that ~20 % of new missense mutations in humans result in a loss of function , whereas ~27 % are effectively neutral . - pubmed
Patients who had advanced , previously untreated diffuse aggressive lymphomas ( IWF E - H ) and an International Prognostic Index of intermediate to high risk were eligible . - pubmed
Six patients have developed AML or MDS . - pubmed
Between April 1996 and October 2004 , 184 patients with germ cell tumor were treated at Indiana University with salvage high - dose chemotherapy ( HDCT ) with autologous peripheral blood stem cell transplant . - pubmed
One additional patient who relapsed after HDCT and was treated with third line chemotherapy followed by two surgical resections of choriocarcinoma is currently alive NED at +90 months from HDCT . - pubmed
Long - term disease - free survival and potential cure is possible with HDCT in choriocarcinoma patients that progressed after standard cisplatin combination therapy . - pubmed
Knowledge of HIV and AIDS among tertiary students in Bangladesh . - pubmed
Plasmapheresis and pregnancy outcome in patients with antiphospholipid syndrome . - pubmed
OBJECTIVE : To assess plasmapheresis with low dose prednisone on obstetric and neonatal outcomes among unsuccessfully treated pregnant women with documented antiphospholipid syndrome ( APS ) . - pubmed
Plasmapheresis may be used to treat pregnant women with documented APS when first lines ( aspirin and/or heparin ) fail to prevent pregnancy loss . - pubmed
Patients were then divided into 2 other groups according to pain onset ( MSCT performed within the first 12 h of pain onset and MSCT performed thereafter ) . - pubmed
CONCLUSION : MSCT should be performed even in patients in whom the clinical suspicion of appendicitis is low . - pubmed
MSCT is effective in patients with early - stage appendicitis . - pubmed
In this study , we investigated the quantitative and qualitative changes in NKT cells in bone marrow ( BM ) mononuclear cells of AA patients in response to in vitro stimulation with alpha - galactosylceramide . - pubmed
Compared to healthy controls , BM from AA patients had reduced fraction of NKT cells , which possessed a decreased potential to expand in vitro in response to alpha - galactosylceramide stimulation , producing more IFNgamma + NKT1 cells . - pubmed
RESULTS : Overall , among the 51 patients with intended complete tumour removal , iMRI revealed definite tumour remnants or suspicious findings in 13 patients ( 25.5 % ) , leading to an extended resection and allowing completion of the resection in 10 patients . - pubmed
The protective effect of fish n-3 fatty acids on cerebral ischemia in rat prefrontal cortex . - pubmed
Cerebral ischemia and reperfusion was produced in rats either on a standard diet ( Group B ) or a standard diet plus fish n-3 EFA for 14 days ( Group C ) . - pubmed
There were no differences between groups in 4 - year and 8 - year survival rates , with 77.2 % and 61.8 % , respectively , in patients with DSWI compared with 78.0 % and 67.5 % in patients without DSWI ( P = 0.16 ) . - pubmed
Acetic acid induced ulceration in rats is not affected by infection with Hymenolepis diminuta . - pubmed
Analysis of rodent models of inflammatory bowel disease , airways hyper - reactivity , diabetes , and multiple sclerosis has shown that infection with helminth parasites can significantly reduce the severity of the disease . - pubmed
Here , we assessed whether rats infected with the tapeworm Hymenolepis diminuta were protected from gastric ulceration induced by the serosal application of acetic acid . - pubmed
All rats gavaged with infective cysticercoids harbored adult worms when assessed 6 wk later , and acetic acid evoked the expected gastric ulceration . - pubmed
However , infection with H. - pubmed
While the data do not dismiss the possibility that infection with other helminths could be anti - ulcerogenic , they illustrate that ' helminth therapy ' for inflammatory disease is likely to be both disease- and helminth - specific . - pubmed
All patients with anemia secondary to CKD should be treated and evaluated for possible treatment , irrespective of underlying disease , associated comorbidity or possibility of kidney replacement therapy . - pubmed
In all cases and for all ESAs , the subcutaneous route is the recommended route of administration for patients with CKD ( Strength of Recommendation C ) . - pubmed
There is insufficient evidence in patients with CKD to justify routine use of coadjuvant treatments . - pubmed
Amlodipine reduces predicted risk of coronary heart disease in high - risk patients with hypertension in Spain ( The CORONARIA Study ) . - pubmed
We evaluated the efficacy and safety of amlodipine besylate alone or in combination with other antihypertensive agents in high - risk hypertensive patients in Spanish primary care . - pubmed
In this 1 - year , open - label , prospective cohort study , 7468 patients were treated with amlodipine 5 - 10 mg as a monotherapy or as an add - on therapy to attain blood pressure control ( target of & lt ; 140/90 mmHg or , in patients with conditions such as diabetes or chronic kidney disease , & lt ; 130/85 mmHg ) . - pubmed
Frontal bandeau reconstruction with a fibula flap in a patient with Freeman - Sheldon syndrome . - pubmed
This case is unique in that a free fibula flap had never been used to obliterate the frontal sinus in a patient with Freeman - Sheldon syndrome , nor had it been harvested from a limb with a clubfoot . - pubmed
This report describes the case of a 32 - year - old woman who has been experiencing temporomandibular joint ankylosis for a period of 8 years . - pubmed
An analysis of treatment of 133 patients with acute pancreatitis using minimally invasive surgical interventions ( laparoscopic and puncture - draining operations ) has shown that in cases of total pancreonecrosis these methods were little effective in most cases as a definitive method of surgical treatment and may be considered as the first stage of complex process of treatment . - pubmed
However , for certain forms of pancreonecrosis the minimally invasive surgery plays one of the leading roles in the improvement of results of treatment in the general population of patients with destructive pancreatitis . - pubmed
Predictors of surgical outcome in children with vesicoureteral reflux associated with paraureteral diverticula . - pubmed
METHODS : Records of 51 patients who underwent surgical treatment for PUD were reviewed . - pubmed
Morphofunctional changes in the thyroid gland in animals with the central and peripheral mechanisms of the development and regression of the nonthyroid disease syndrome were detected . - pubmed
OBJECTIVE : To compare length of stay , readmissions , infections , and mortality in patients with end - stage renal disease who have been admitted to receive renal transplant , stratified according to diabetes status and admission glucose concentration . - pubmed
Patients were stratified according to diabetes status before transplant and glucose concentration at hospital admission ( hyperglycemic [ & gt ; 180 mg / dL ] or normoglycemic [ & lt;= = 180 mg / dL ] ) . - pubmed
When stratified according to glucose concentration at admission , patients with hyperglycemia had a significantly longer length of stay than normoglycemic patients ( 10 + - 4.3 days vs 7.9 + - 2.9 ; P = .039 ) , even after correcting for diabetes status . - pubmed
CONCLUSION : Hyperglycemia at hospital admission , rather than a known diagnosis of diabetes , is associated with increased length of stay in patients admitted for renal transplant . - pubmed
Human papillomavirus ( HPV ) testing is routinely performed on oropharyngeal carcinomas . - pubmed
ISH and AGPCR have comparable performance for the detection of HPV in oropharyngeal carcinomas . - pubmed
PCR is a suitable and economical assay that is comparable to ISH in sensitivity and may provide logistical advantages relative to ISH for assessing HPV status in oropharyngeal malignancies . - pubmed
PATIENTS AND METHODS : Forty patients with hip fractures with normal contralateral hips were selected for this study between 2003 and 2007 ( trochanteric fracture , n=18 ; femoral neck fracture , n=22 ) . - pubmed
Patients with trochanteric fractures showed a smaller neck shaft angle and smaller cortical index at the femoral canal isthmus compared with patients with femoral neck fractures . - pubmed
CONCLUSIONS : We conclude that severe osteoporosis with thinner cortical bone of the femoral diaphysis is seen more often in patients with trochanteric fracture than in patients with femoral neck fracture . - pubmed
OBJECTIVE : To document the influence of age on step activity patterns in children with cerebral palsy ( CP ) and typically developing ( TD ) children . - pubmed
Seizure and altered mental status in a 12 - year - old child with Shigella sonnei gastroenteritis . - pubmed
We report here the first case of SLE - induced DAH treated successfully with rituximab without cyclophosphamide administration in a patient intolerant to cyclophosphamide . - pubmed
Thus , CMR perfusion stress testing has been deemed appropriate for the evaluation of chest pain syndromes in patients with intermediate probability of coronary artery disease ( CAD ) and for ascertaining the physiologic significance of indeterminate coronary artery lesions . - pubmed
Probiotics are able to decrease the permeability of the intestinal wall , and decrease bacterial translocation and endotoxemia in animal models as well as in clinical studies , which is extremely important in the prevention of complications of liver cirrhosis and infection after liver transplantation . - pubmed
Peak nasal inspiratory flow ( PNIF ) can help in the assessment of patients with allergic rhinitis . - pubmed
METHODS : : A retrospective analysis of all patients undergoing repair of AAA during 2007 . - pubmed
The endovascular group included three patients with contained retroperitoneal rupture , one of whom died secondary to visceral embolization and thrombosis ( the only mortality ) . - pubmed
Defects in this response can result in airway remodeling , such as mucus cell metaplasia ( MCM ) , commonly seen in patients with chronic lung disease . - pubmed
The effects of Pilates on metabolic control and physical performance in adolescents with type 1 diabetes mellitus . - pubmed
UNLABELLED : Physical activity is a substantial method in the management of children and adolescents with Type 1 diabetes mellitus but it is not considered as a treatment for diabetes . - pubmed
The aim of this study was to investigate the effects of Pilates exercises on metabolic control and physical performance in patients with type 1 diabetes mellitus . - pubmed
Thirty one sedentary patients with type 1 diabetes mellitus , ranging in age from 12 to 17 ( experimental group , n=17 and control group , n=14 ) were submitted to 12 weeks of Pilates training . - pubmed
CONCLUSIONS : Physical performance increased via Pilates exercises in the patients with type 1 DM . - pubmed
In the present study , the positive effects of exercise on metabolic control could not be shown in patients with Type 1 DM . - pubmed
Twenty - three heat - sensitive MS subjects and 19 healthy controls participated . - pubmed
pneumoniae , Neisseria meningitidis type C ( MenC ) , and/or Haemophilus influenzae type b ( Hib ) . - pubmed
In the current study we examined the effects of 27 - and 24 - hydroxycholesterol on viability of human neuroblastoma SH - SY5Y cells treated with staurosporine , a toxic substance that induces apoptosis . - pubmed
These genes code for two enzymes involved in fatty - acid metabolism , and we have demonstrated in human cells that the HSP pathophysiology includes alteration of mitochondrial architecture and bioenergetics with increased oxidative stress . - pubmed
Systemic administration of human adipose - derived stem cells reverts nociceptive hypersensitivity in an experimental model of neuropathy . - pubmed
We have investigated the effect of hASCs injected in a model of neuropathic pain [ ( mouse sciatic nerve chronic constriction injury ( CCI ) ] . - pubmed
No mouse died , and no macroscopic toxicity or behavioral changes were observed , confirming the safety of hASCs . - pubmed
injected into C57BL / 6 mice when the neuropathic pain was already established , induced a significant reduction in mechanical allodynia and a complete reversion of thermal hyperalgesia in a dose - response fashion , already 1 day after administration . - pubmed
In some patients , optic neuropathy may improve with intravitreal steroids or anti - angiogenic agents . - pubmed
For applications that are geared towards children , such as retinal birefringence scanning for strabismus screening purposes , it is important to know the expected range of both corneal retardance and azimuth in pediatric populations . - pubmed
Breastfed infants are at especially high risk of vitamin D deficiency due to poor penetrance of vitamin D metabolites into milk . - pubmed
Resolution of intracardiac and pulmonary thrombi without anticoagulation in a patient with Behcet ' s disease : a case report . - pubmed
We report a patient who was found to have multiple right intraventricular and bilateral pulmonary artery thrombi and was clinically diagnosed with Behcet ' s disease . - pubmed
We conclude that intracardiac thrombi in patients with Behcet ' s disease may resolve with immunosuppressants without anticoagulation , which is especially important in patients with contraindication to anticoagulation . - pubmed
Enrolled patients were diagnosed with PTCL , confirmed by a referenced pathologist , treated with the new chemotherapy ACEP X 6 ( Doxorubicine 75 mg / m2 on day 1 + Cyclophosphamide 1,200 mg / m2 on day 1 + Etoposide 300 mg / m2 on day 1 and Prednisolone 60 mg / m2 from day 1 through day 5 ) and Ifosfamide X 4 ( Ifosfamide 4 grams / m2 on day 1 ) which were given after the completion of the first 6 cycles of ACEP . - pubmed
However , a larger sample is needed to make it an acceptable new combination chemotherapy for PTCLs patients . - pubmed
RESULTS : Eighteen studies with a total of 761 bipolar disorder patients and 919 healthy controls were included . - pubmed
Studies with immunodeficient mice showed that the mouse genetic background does not alter omental milky spot number and size , nor does it affect ovarian cancer colonization . - pubmed
Working memory in ALS patients : preserved performance but marked changes in underlying neuronal networks . - pubmed
The smaller CDA in the patients could be attributed to more ipsilateral cortical activity which may indicate that ALS patients unnecessarily processed the irrelevant stimuli as well . - pubmed
We report herein two cases of patients with lesions clinically and microscopically compatible with the diagnosis of circumscribed palmoplantar hypokeratosis . - pubmed
OBJECTIVE : To discuss the drug intervention in diversity changes of TCRVbeta gene in AIDS patients with incomplete immune reconstitution . - pubmed
METHOD : PBMCs were isolated from 37 cases of AIDS patients failure to immune reconstitution before and after treatment with immune 2 and 15 cases of HIV negative healthy donors . - pubmed
Embryonic exposure to corticosterone modifies aggressive behavior through alterations of the hypothalamic pituitary adrenal axis and the serotonergic system in the chicken . - pubmed
Female BALB / c mice were randomly assigned to one of the four groups : the negative control group , the parental corn group , the GM corn group and the positive control group with 10 mice per group . - pubmed
The aim of this study was to determine the anticancer effects of urushiol in human gastric adenocarcinoma cell lines . - pubmed
RESULTS : The cytotoxic results from MTT assays indicated that urushiol inhibited human gastric cancer cell growth in a dose - dependent manner , with IC50 values of approximately 15 and 20 mug / ml on MKN-45 and MKN-28 cells , respectively . - pubmed
CONCLUSIONS : These data provide evidence that urushiol has the potential to be used as a chemotherapeutic agent in human gastric cancer . - pubmed
Until the late 1980s , physical exercise training was a contraindication in patients with heart failure . - pubmed
Observational data support lower recurrence rates and improved survival after radioiodine ablation in patients with high - risk cancers ; however , a similar benefit has not been established for all patients with thyroid cancer . - pubmed
METHODS : Peripheral venous blood was sampled from 75 septic patients ( 39 patients with sepsis , 25 with severe sepsis and 11 with septic shock ) on sepsis days 1 , 3 and 7 . - pubmed
MATERIAL AND METHODS : Authors studied 40 patients ( 23 men and 17 women , mean age 31.8 years ) with mild and moderate depression comorbid with symptoms of panic disorders . - pubmed
Magnetic resonance imaging findings in patients presenting with ( sub)acute cerebellar ataxia . - pubmed
Previous magnetic resonance ( MR ) studies in single patients who developed acute or subacute ataxia showed varying imaging features . - pubmed
METHODS : Eighteen patients presenting with acute and subacute onset of ataxia were included in this study . - pubmed
RESULTS : An underlying etiology for ataxic symptoms were found in 14/18 patients ( postinfectious / infectious , paraneoplastic , autoimmune , drug - induced ) . - pubmed
In two of five patients without MR imaging findings and three of eight patients with minimal imaging features ( cerebellar atrophy , slight signal alterations , and small areas of restricted diffusion ) , adverse clinical outcomes were documented . - pubmed
Of the five patients with prominent MR findings ( cerebellar swelling , contrast enhancement , or broad signal abnormalities ) , two were lost to follow - up and two showed long - term sequelae . - pubmed
CONCLUSION : No correlation was found between the presence of initial MRI findings in subacute or acute ataxia patients and their long - term clinical outcome . - pubmed
PATIENTS AND METHODS : 120 patients with ultra - early basal ganglia intracerebral hemorrhage were randomly divided into experimental group ( strengthened antihypertensive ) and control ( normal antihypertensive ) . - pubmed
METHODS AND MATERIALS : From 2005 to 2012 , 18 patients with biopsy proven locally recurrent prostate cancer and negative staging received low - dose - rate BT with a prescribed dose of 130 - 144 Gy . - pubmed
Late Grade 3/4 genitourinary toxicity occurred in 1 patient each , one of whom also had Grade 3 late gastrointestinal toxicity ; urethral strictures developed in three others . - pubmed
These 5 patients with late toxicity had higher dose to the prostate ( isodose enclosing 90 % [ D90 ] median , 151 Gy ; range , 135 - 185 Gy ) compared with those without late complications ( median , 134 Gy ; range , 105 - 165 ; p & lt ; 0.04 ) . - pubmed
Considering drug metabolism and pharmacokinetics , we have established nonclinical animal models of DILI for 10 types of clinical drug known to cause idiosyncratic DILI in humans . - pubmed
Using animal models , it has been shown that the formation of reactive metabolites and both innate and adaptive immunity are involved in the pathogenesis of drug hepatotoxicity . - pubmed
Based on information on biomarkers obtained from animal models , we developed a cell - based system that predicts the potential DILI risks of drugs . - pubmed
A study of cognitive functions in female elderly patients with osteoporosis : a multi - center cross - sectional study . - pubmed
METHODS : This cross - sectional study included 277 postmenopausal women , who were divided into an osteoporosis patients group ( n = 170 ) and an age , gender and educational history matching control group ( n = 107 ) . - pubmed
RESULTS : Individuals with osteoporosis had poorer cognitive scores ( P & lt ; 0.001 ) . - pubmed
CONCLUSIONS : Patients with osteoporosis are prone to cognitive impairments especially declarative memory deficits . - pubmed
Experiments were conducted with four neutrophilic bacterial strains , including the Gram - negative Escherichia coli and Pseudomonas putida and the Gram - positive Bacillus subtilis and Staphylococcus epidermidis . - pubmed
Evaluating Human T - Cell Therapy of Cytomegalovirus Organ Disease in HLA - Transgenic Mice . - pubmed
The model has thus proven its potential for a preclinical testing of the protective antiviral efficacy of HCMV epitope - specific human T cells in the evaluation of new approaches to an immunotherapy of CMV disease . - pubmed
Sleep - associated aspects of myofascial pain in the orofacial area among Temporomandibular Disorder patients and controls . - pubmed
STUDY OBJECTIVES : To assess sleep - associated aspects of temporomandibular disorder ( TMD ) with myofascial pain ( MP ) in the orofacial area of patients and controls . - pubmed
MEASUREMENTS : Three hundred five female patients were screened to find 44 participants fulfilling the inclusion criteria , 22 suffering from MP and 22 in a control group . - pubmed
Selenoprotein T Deficiency Leads to Neurodevelopmental Abnormalities and Hyperactive Behavior in Mice . - pubmed
Introducing germplasm from exotic sources especially from another cultivated tetraploid G. - pubmed
Chronic West Nile virus infection in kea ( Nestor notabilis ) . - pubmed
OBJECTIVE : To compare secondary conditions in people with traumatic spinal cord injury ( SCI ) and non - traumatic spinal cord dysfunction ( SCDys ) . - pubmed
PARTICIPANTS : Adults with spinal cord damage from any cause . - pubmed
A genome - wide expression profile analysis reveals active genes and pathways coping with phosphate starvation in soybean . - pubmed
The Effect of Radiotherapy on Ultrasound - Guided Fine Needle Aspiration Biopsy and the Ultrasound Characteristics of Neck Lymph Nodes in Oral Cancer Patients after Primary Treatment . - pubmed
OBJECTIVES : To investigate the effect of radiotherapy ( RT ) on ultrasound - guided fine needle aspiration ( USgFNA ) and sonographic characteristics in the assessment of cervical lymph nodes ( LNs ) in oral squamous cell carcinoma ( OSCC ) patients after primary treatment . - pubmed
MATERIALS AND METHODS : 88 treated OSCC patients underwent 111 USgFNAs of the neck LNs after US evaluation . - pubmed
CONCLUSIONS : RT had influence on sonographic characteristics but no influence on USgFNA in diagnosing recurrent LNs in treated OSCC patients . - pubmed
Therefore , changes in commensal microbiota associated with CRS may alter the normal microbe host dialogue in humans and be implicated in the pathogenesis of CRS . - pubmed
BACKGROUND : The Modification of Diet in Renal Disease ( MDRD ) equation is widely used to estimate glomerular filtration rate ( eGFR ) in kidney transplant ( KT ) patients . - pubmed
Our aim was to compare both equations for staging of CKD in KT patients . - pubmed
METHODS : In a cohort of KT patients , correlation of eGFR according to MDRD and CKD - EPI with 24 - hour creatinine clearance ( 24h - CrCl ) was evaluated . - pubmed
CONCLUSIONS : The novel CKD - EPI reduces the number of patients with eGFR & lt;60 mL / min/1.73 m(2 ) and consequently assigns lower CKD stages to our KT population . - pubmed
Pathogenic and viral infections such as Enterotoxigenic E. - pubmed
coli ( ETEC ) and porcine epidemic diarrhea virus can lead to loosening the intestinal epithelial barrier . - pubmed
We report a 70 - year - old man with prostate cancer and multiple abdominal , pelvic , and inguinal node metastases . - pubmed
Assessment of atrial conduction times in prediabetic patients with coronary artery disease . - pubmed
We evaluated atrial conduction times ( ACTs ) and atrial electromechanical delays ( EMDs ) in prediabetic patients with coronary artery disease ( CAD ) . - pubmed
METHODS : In the present study , we recruited 128 consecutive patient candidates ( 40 euglycemic , 48 prediabetic , and 40 diabetic patients ) for coronary artery bypass grafting . - pubmed
CONCLUSION : There were no significant differences between the euglycemic , prediabetic , and diabetic patients with CAD regarding ACTs and atrial EMDs . - pubmed
Evaluation of adaptive treatment planning for patients with non - small cell lung cancer . - pubmed
The purpose of this study was to develop metrics to evaluate uncertainties in deformable dose accumulation for patients with non - small cell lung cancer ( NSCLC ) . - pubmed
Adaptive planning helps escalate target dose and spare normal tissue for patients with NSCLC , but deformable dose accumulation may have a significant loss of energy in regressed tumor volumes when using image intensity - based DIR algorithms . - pubmed
The metric of energy defect is a useful tool for evaluation of adaptive planning accuracy for lung cancer patients . - pubmed
Here , we challenge the existence of the idea of noninfectious sepsis given that critically ill humans never exist in a germ - free state . - pubmed
BACKGROUND / AIMS : The thaliana phytoalexin Camalexin has been proposed for the treatment of malignancy . - pubmed
A review of the efficacy of atomoxetine in the treatment of attention - deficit hyperactivity disorder in children and adult patients with common comorbidities . - pubmed
Importantly , up to 52 % of children ( including adolescents ) and 87 % of adults with ADHD also have a comorbid psychiatric disorder . - pubmed
Despite numerous published studies regarding efficacy of atomoxetine in the treatment of ADHD in patients with comorbid disorders , there is limited information about the impact of individual common comorbid disorders on the efficacy of atomoxetine for ADHD , especially with regard to adults . - pubmed
For this reason , we performed a literature review to find , identify , and cumulatively review clinical studies that examined the efficacy of atomoxetine in the treatment of patients with ADHD and comorbid psychiatric disorders . - pubmed
We found a total of 50 clinical studies ( 37 in children ; 13 in adults ) that examined the efficacy of atomoxetine in patients with ADHD and a comorbid disorder . - pubmed
The comorbidities that were studied in children or in adults included anxiety , depression , and substance use disorder . - pubmed
Overall , the presence of comorbidity did not adversely impact the efficacy of atomoxetine in treatment of ADHD symptoms in both patient populations . - pubmed
Human herpesvirus-8 and human cytomegalovirus infections in Bowen ' s disease : Is there any association ? - pubmed
RESULTS : The patient was admitted at the age of 5 months due to severe epilepsy and marked delayed psychomotor development . - pubmed
In present review , an attempt has been made to generate awareness among the readers about various sources of occurrence of arsenic , its geochemistry and speciation , mobilization , metabolism , genotoxicity , and toxicological exposure on humans . - pubmed
SSMT is otherwise uncommon with an incidence of up to 7 % in asymptomatic individuals . - pubmed
The aim of this study was to evaluate the incidence and clinical significance of SSMT in patients with PA and a control group of surgically treated non - functioning pituitary adenomas ( NFPAs ) . - pubmed
METHODS : Retrospective review of clinical and imaging variables in PA and NFPA patients . - pubmed
PA patients were managed conservatively ( N = 11 ) or surgically ( N = 36 ) . - pubmed
Physiological factors such as liver fluke ( Fasciola hepatica ) infection , breeding status , and in - tissue element interactions may also affect tissue concentrations , though their effects in red deer are not well understood . - pubmed
These tumors can be found in all age groups , but are more common in older patients ; with the cutaneous form most common in older white men . - pubmed
CASE PRESENTATION : Here we describe the case of a 63 - year - old man who presented initially with angiosarcoma of the nose and received surgery for the primary . - pubmed
The most active hydrolysate was then tested for blood pressure - lowering ability in spontaneously hypertensive rats ( SHRs ) . - pubmed
METHODOLOGY AND PRINCIPAL FINDINGS : Ninety - three unrelated individuals with molecularly unassigned spinocerebellar ataxia selected from 585 pedigrees with autosomal dominant cerebellar ataxias , were recruited into the study with elaborate clinical evaluations . - pubmed
The treatment of patients with TNBC remains a great clinical challenge . - pubmed
We present the case of a female 34 - year - old patient with acute kidney injury symptoms with indication for renal replacement therapy in the context of clinical SLE diagnosis . - pubmed
We isolated 75 Cercomonadida strains from the phyllosphere and rhizosphere of plants from three functional groups : grasses ( Poa sp . ) , legumes ( Trifolium sp . ) and forbs ( Plantago sp . ) - pubmed
A systematic review of literature from 2011 to 2016 was performed , in order to evaluate the diagnostic performance of inflammatory biomarkers in children with fever without apparent source and their usefulness in clinical decision - making . - pubmed
Recently , microRNA-372 ( miR372 ) has been proven to play a substantial role in several human cancers , but its functions in liver cancer remain unclear . - pubmed
We report a 44 - year - old woman with anemia and uterine IMT . - pubmed
Our aim was to investigate the effects of a MAP - guided management in a bleeding - resuscitation animal experiment . - pubmed
First Pediatric Case of Infective Endocarditis Caused by Serratia Liquefaciens . - pubmed
Infective endocarditis ( IE ) caused by Serratia liquefaciens has been reported in only 2 adults . - pubmed
We experienced the first pediatric ( neonatal ) case of IE caused by S. - pubmed
OBJECTIVE : Home nebulizers are routinely used in the treatment of patients with cystic fibrosis ( CF ) . - pubmed
This study aims to evaluate the contamination of nebulizers used for CF patients , that are chronically colonized by Pseudomonas aeruginosa , and the association of nebulizer contamination with cleaning , decontamination and drying practices . - pubmed
Genetic Profiling of Aggregatibacter actinomycetemcomitans Serotype B Isolated from Periodontitis Patients Living in Sweden . - pubmed
The bacterium Aggregatibacter actinomycetemcomitans is associated with aggressive forms of periodontitis and with systemic diseases , such as endocarditis . - pubmed
We describe frequent T - cell - based immune responses against this epitope in patients with cancer , as well as in healthy donors . - pubmed
We here report the results of an uncontrolled case series of patients with refractory tremor who underwent deep brain stimulation under tractographic assistance . - pubmed
In this study , we attempt to explore the prognostic significance of the AAPR in stage IB - IIA cervical cancer patients who underwent a radical hysterectomy . - pubmed
Patients and methods : A total of 230 cervical cancer patients were enrolled in this retrospective study . - pubmed
Conclusion : Preoperative AAPR was a potentially valuable prognostic index in stage IB - IIA cervical cancer patients . - pubmed
We present 3 patients successfully treated for their septal perforation and septal deviation concurrently with this technique . - pubmed
In the 47 patients who survived for longer than 9 months and were evaluated for BOS after the transplant , BOS was not related to DSA or PRA levels . - pubmed
Zanubrutinib for the treatment of patients with Waldenstrom macroglobulinemia : three years of follow - up . - pubmed
Patients had disease requiring treatment per International Workshop on Waldenstrom Macroglobulinemia ( IWWM ) criteria . - pubmed
At a median follow - up of 36.0 months for patients with R / R disease and 23.5 months for TN , 72.7 % remained on treatment . - pubmed
Reasons for treatment discontinuation included any adverse events in 13.0 % of patients ( 1 treatment related ) , disease progression ( 10.4 % ) , and other ( 3.9 % ) . - pubmed
Long - term treatment with single - agent zanubrutinib resulted in deep and durable responses in some patients with WM . - pubmed
Marker chromosome is a strong poor prognosis factor after allogeneic HSCT for adverse - risk AML patients . - pubmed
OBJECTIVE AND METHODS : We retrospectively analyzed 162 AML patients after allo - HSCT . - pubmed
RESULT : MC was detected in 14 ( 8.6 % , MC+ ) patients ( vs. MC- , n=158 ) . - pubmed
Desmopressin acetate decreases blood loss in patients with massive hemorrhage undergoing gastrointestinal surgery . - pubmed
This study was to investigate whether DDAVP can decrease blood loss in patients with massive hemorrhage undergoing gastrointestinal surgery . - pubmed
88 patients were divided into moderate ( 47 [ 53.41 % ] ) , severe ( 32 [ 36.36 % ] ) and critically ill ( 9 [ 10.23 % ] ) groups . - pubmed
Newly synthesized derivatives were evaluated for their anticancer potential against human malignant glioma U87 ( MG - U87 ) cell lines at different concentrations of 200 muM , 100 muM , 50 muM , 25 muM , 12.5 mum , 6.25 mum and 0 muM. - pubmed
They are especially indicated for patients who have conditions producing pain of short duration or for terminal patients . - pubmed
Radiotherapy may temporarily help most patients with intractable pain . - pubmed
Open or stereotactic surgical intervention and especially interruption of the ascending pain fibers within the spinal cord may give permanent relief to patients who have increasingly severe pain . - pubmed
Partial characterization of a fetal lung antigen associated with human bronchogenic carcinoma . - pubmed
Twelve arches in eight patients with moderate to severe bone loss were selected for this investigation . - pubmed
Fasting & amp ; postprandial blood sugar studies in treated & amp ; untreated diabetic patients . - pubmed
Relationship of the constituents of bile to biliary peritonitis in the rat . - pubmed
This paper describes an animal model to determine which of the major solid components of bile are responsible for peritoneal destruction in biliary peritonitis . - pubmed
In the rat , bile salts within the peritoneal cavity cause peritonitis but cholesterol and lecithin are without deleterious effect . - pubmed
Renal tissue from 6 patients with glomerulonephritis associated with cryoglobulinemia was studied by light microscopy , immunofluorescence microscopy , and electron microscopy . - pubmed
Proceedings : An improved technique for producing hemorrhageous erosions in the female rat : its application in studies on the role of histamine in stress ulcer pathogenesis . - pubmed
Hepatic cholesterol metabolism in patients with gallstones . - pubmed
Obstructive hydrocephalus was induced in 12 - day - old rats by the infusion of kaolin into the cisterna magna . - pubmed
Loss of righting reflex ( precoma stage of PSE ) was accompanied by 2 - 3 fold increased CSF lactate and onset of coma by 4 - fold increases of lactate ( p less than 0.001 compared to either sodium acetate treated portacaval shunted rats or sham - operated controls administered ammonium acetate ) . - pubmed
Similar mechanisms could be involved in the pathogenesis of PSE in patients with chronic liver disease . - pubmed
The biodistribution in mice bearing melanoma either human or animal from 4 to 24 hrs . - pubmed
Nevertheless , the combination of surgery and postoperative chemotherapy helped to prolong the life of patients with Wilms ' tumors . - pubmed
B19 parvovirus infection is a principal cause of transient bone marrow suppression in patients with chronic haemolytic anaemias . - pubmed
BACKGROUND : Clinical vitamin A deficiency affects millions of children worldwide , and subclinical deficiency is even more common . - pubmed
The base - line characteristics of the children were similar and documented a high prevalence of vitamin A deficiency and undernutrition . - pubmed
The risk was most reduced among children under 3 years of age ( 6 to 11 months -- relative risk , 0.28 ; 95 percent confidence interval , 0.09 to 0.85 ; 12 to 35 months -- relative risk , 0.46 ; 95 percent confidence interval , 0.26 to 0.81 ) and among those who were chronically undernourished , as manifested by stunting ( relative risk , 0.11 ; 95 percent confidence interval , 0.03 to 0.36 ) . - pubmed
Unilateral degeneration of retina and optic nerve in Fischer-344 rats . - pubmed
Unilateral degeneration of the retina and optic nerve was observed among Fischer-344 ( F-344 ) rats fed a semi - purified synthetic feed . - pubmed
No ocular lesions were observed in any F-344 rats prior to 21 weeks of age , whether fed a synthetic diet or a standard diet ; however , approximately 16 % ( 13/86 ) of the F-344 rats examined between 57 and 64 weeks of age developed unilateral degeneration of the retina and optic nerve . - pubmed
On the other hand , the F-344 rats fed the synthetic diet developed the degenerative lesions by 30 weeks of age , while the F-344 rats fed the standard diet did not develop lesions over this shorter time period . - pubmed
In contrast with the F-344 rats , Long - Evans rats that were fed either the synthetic or standard diet up to the age of 68 weeks ( 77 rats ) did not develop the ocular lesions . - pubmed
There was no apparent relationship of the development of the lesions with dietary modification , toxicity or trauma ; thus , these observations appear to indicate that spontaneous unilateral degeneration of the retina and optic nerve occurs in F-344 rats and that these ocular lesions may be accelerated by the feeding of certain semi - purified synthetic diets . - pubmed
Food intake per 100 g body weight was significantly increased between postoperative days 14 and 35 in the jejunoileal bypass rats . - pubmed
Bacterial tracheitis caused by Branhamella catarrhalis . - pubmed
Although the cause of death was cardiac related in 50 % of the patients who died , survival was comparable with that of an age - matched and sex - matched general population . - pubmed
Acute event - free status ( freedom from acute myocardial infarction , repeat coronary artery bypass grafting , percutaneous transluminal coronary angioplasty , or death ) persisted at 15 years in 43.2 % of patients . - pubmed
Prevention of DOCA - induced hypertension in rats by chronic treatment with tryptophan . - pubmed
Hypertension developed within 5 weeks in uninephrectomized rats administered deoxycorticosterone acetate ( DOCA , 30 mg / kg , s.c . - pubmed
Treatment with tryptophan also protected against the reduction in urinary concentrating ability during a 24 h dehydration that is characteristic of DOCA - treated rats . - pubmed
These results suggest that tryptophan provides significant protection against the development of DOCA - induced hypertension , polydipsia , and cardiac hypertrophy in rats . - pubmed
Two patients with small cell carcinoma of the lung who presented with lactic acidosis are described . - pubmed
In 62 untreated patients with essential hypertension , arterial baroreflex sensitivity ( BRS ) for heart rate , i.e. - pubmed
A series of earlier studies showed that inhalation exposures of rats to three water - reactive electrophilic compounds produced brisk yields of nasal cancer even when the animals were exposed for only 30 days ( 6 hr / day X 5 day / wk ) . - pubmed
With this protocol , all compounds except PO ( the slowest reacting compound ) produced nasal cancer in rats . - pubmed
The concentrations of MMS and BPL employed in the studies produced similar nasal cancer yields , indicating that the carcinogenic potencies of these compounds in rat nasal mucosa were proportional to their hydrolysis rates . - pubmed
The single breath diffusing capacity of the lung for carbon monoxide ( Dsb ) was measured using three equations to describe CO uptake separately during inhalation , breath holding , and exhalation in 24 patients with cystic fibrosis and 30 control subjects with similar age and height distributions . - pubmed
In a multicenter study 153 in- and outpatients suffering from severe pain were treated for three weeks with capsules containing 50 mg 1 -( m - methoxyphenyl )- 2 -( dimethylaminomethyl )- cyclohexan-1 - ol ( tramadol , Tramal ) . - pubmed
Protective effect of polyphloretin phosphate in anaphylaxis in the guinea pig . - pubmed
[ Reticuloendothelial blockers -- effects of carrageenan and dextran sulfate on the function of the mouse mesangium in processing foreign bodies ] . - pubmed
Two - stage carcinogenesis studies with asbestos in Fischer 344 rats . - pubmed
The systemic absorption of amphotericin B , administered as a 10 mg lozenge , was investigated in 14 patients with malignancies , who received three or four doses daily during chronic administration . - pubmed
[ Pathologic correlation between periodontal disease and diabetes mellitus in a patient with metabolism disorders ] . - pubmed
The minimum inhibitory concentrations of 45 antimicrobial agents were established by the agar dilution method for 37 strains of Bacteroidaceae : Bacteroides fragilis ( 18 strains ) , B. - pubmed
thetaiotaomicron ( 8 strains ) , Fusobacterium nucleatum ( 6 strains ) , and Fusobacterium spp . - pubmed
Three quaternized compounds elicit a significative but low antileukemic activity on L1210 mice leukemia . - pubmed
A two - phase liquid - culture system was used to substantially amplify and differentiate erythroblasts , starting with mononuclear cells from the blood of normal adults , newborn infants , and patients with sickle cell anemia . - pubmed
A patient was diagnosed with Cushing ' s syndrome during her first pregnancy . - pubmed
The retinal electrophysiology is reported in four patients with type II mesangiocapillary glomerulonephritis and partial lipodystrophy with associated fundus abnormalities and no visual symptoms . - pubmed
The appearance of a second neoplasm in these patients represents an important decrease in survival . - pubmed
RESULTS : Ten of the 78 patients studied ( 13 % ) developed a second neoplasm . - pubmed
In 9 of the 10 patients the appearance of the second neoplasm was considered metachronic with 60 % being detected within the first 24 months after the diagnosis of the laryngeal neoplasm . - pubmed
Survival of the patients with the second neoplasm was lower : 71 % at 2 years and 5 % at 5 years ( p & lt ; 0.0001 ) . - pubmed
CONCLUSIONS : The presence of a second neoplasm in patients with laryngeal cancer is high . - pubmed
The survival of patients with advanced laryngeal cancer who develop a second neoplasm is significantly lower than that of other patients with this neoplasm . - pubmed
We report the case of a 40 year old woman , presenting with progressive respiratory failure and bilateral pulmonary infiltrates . - pubmed
A case of unilateral vitreous relapse in a patient with primary central nervous system lymphoma ( PCNSL ) following sequential systemic chemotherapy and radiotherapy is reported . - pubmed
Kidney biopsies were performed in 7 patients : 4 HIV - associated nephropathies ( HIV AN ) with segmental and focal hyalinizations , 1 thrombotic angiopathy , and 2 interstitial nephropathies , 1 with proliferative glomerulonephritis . - pubmed
The clinical , biological and radiographic patterns of 2 of the remaining 3 patients were suggestive of HIV AN . - pubmed
Four of the 6 patients with HIV AN developed end - stage renal disease within 5 + /- 2.5 months ; renal function in the other 2 remained stable for 25 and 41 months , respectively , while they were receiving zidovudine , but deteriorated rapidly within weeks of withdrawing this drug . - pubmed
Zidovudine may have delayed the evolution of the nephropathies in these patients . - pubmed
OBJECTIVE : The authors determined which combination of computed tomography scans is most helpful for preoperative assessment of patients with liver tumors . - pubmed
SUMMARY BACKGROUND DATA : Multi - institutional studies have shown that the most important prognostic factors for selection of patients with metastatic colorectal cancer considered for liver resection are : Dukes ' stage of primary tumor , the number of hepatic metastases if greater than 3 , the presence of extrahepatic cancer , and the ability to resect tumors with an adequate margin ( & gt ; 1 cm . ) - pubmed
Therefore the ability to predict the presence of extrahepatic disease and the number and location of hepatic tumors are important in these patients . - pubmed
METHODS : One hundred and nine consecutive patients with evidence of hepatic tumors were evaluated by computed tomography with arterial portography ( CTAP ) and abdominal computed tomography after a 4 - hour delay ( CT - D ) . - pubmed
METHODS : Thirty two biopsy specimens of Kaposi sarcoma ( 29 patients ) were studied . - pubmed
Effect of thyroid substitution on hypercholesterolaemia in patients with subclinical hypothyroidism : a reanalysis of intervention studies . - pubmed
( 2 ) Precision weighted pooled estimates of the effect of thyroid substitution therapy on the plasma levels of total cholesterol , in patients with subclinical and overt hypothyroidism . - pubmed
RESULTS : Subclinical hypothyroidism was two to three times more frequent in people with an elevated total plasma cholesterol . - pubmed
In addition , the total plasma cholesterol levels were slightly elevated in patients with subclinical dysfunction of the thyroid . - pubmed
The effect of thyroid substitution in patients with overt hypothyroidism was highly dependent on the pretreatment levels of total cholesterol . - pubmed
CONCLUSIONS : Thyroid substitution treatment in patients with hypercholesterolaemia and subclinical hypothyroidism decreases total plasma cholesterol by 0.4 mmol / l , but plasma levels remain elevated in most patients . - pubmed
Mutations in the long control region of human papillomavirus DNA in oral cancer cells , and their functional consequences . - pubmed
Oral cancers frequently contain DNA of human papillomavirus ( HPV ) type 16 or 18 , but the functional significance of this is unclear . - pubmed
A role for HPV in the progression of oral cancer would be more plausible if the viral transforming genes were likely to be overexpressed in oral cancer cells . - pubmed
We therefore isolated and sequenced the long control region ( LCR ) of HPV-16 or HPV-18 from three oral cancer cell lines and two lines of HPV-16 - immortalized oral keratinocytes , using PCR . - pubmed
These results imply that mutations in the LCR of HPVs in oral cancer could lead to increased expression of HPV - transforming proteins , which might contribute to the carcinogenic process . - pubmed
While strain M3GY could grow on DPE , cells grown on DPE as a sole carbon source could not degrade DDE . - pubmed
We have tested how the plasma of patients with acute myocardial infarction affects this process . - pubmed
METHODS AND RESULTS : Citrated plasma was obtained from 18 patients with acute myocardial infarction within 6 hours from the onset of symptoms and from 26 control subjects with chest pain syndrome without evidence of ischemia . - pubmed
those patients with genetic or acquired lymphopenia . - pubmed
Matching donors and recipients for HCV genotype may minimize the risk of superinfection when using kidneys from HCV - positive donors ( RR 1.4 , p = 0.02 for the D+/R- mismatch ) . - pubmed
To study sensitivity and poliovirus serotype - specificity , 129 sera and 115 CSF specimens from children with acute poliomyelitis were used in comparative tests with the in - house RIA . - pubmed
SUBJECTS : 129 obese children ( 67 girls and 62 boys ) , 142 normal - weight controls ( 81 boys and 61 girls ) , and mothers ( n = 245 ) and fathers ( n = 222 ) of the children . - pubmed
AIMS : To investigate the effect of alosetron on whole gut , small bowel and colonic transit in patients with irritable bowel syndrome ( Study 1 ) and healthy volunteers ( Study 2 ) . - pubmed
SUBJECTS : Thirteen patients with irritable bowel syndrome and 12 healthy volunteers . - pubmed
RESULTS : Alosetron increased colonic transit time by prolonging left colonic transit in both patients with irritable bowel syndrome and controls . - pubmed
This resulted in a tendency for the whole gut transit to be delayed in irritable bowel syndrome patients ( P=0.128 ) , which was confirmed in controls ( P=0.047 ) . - pubmed
These results add to the body of evidence suggesting that alosetron should have a therapeutic role in patients with non - constipated irritable bowel syndrome . - pubmed
These regions may also overlap with the syntenic region of the glomerulosclerosis susceptibility locus in the BUF / Mna rat . - pubmed
Biodistribution of paclitaxel and poly ( L - glutamic acid )- paclitaxel conjugate in mice with ovarian OCa-1 tumor . - pubmed
METHODS : Female C3Hf / Kam mice bearing syngeneic ovarian OCa-1 tumors were injected with either [ 3H ] TXL or PG -[ 3H ] TXL at an equivalent TXL dose of 20 mg / kg . - pubmed
Mice were killed at various times after drug injection , and samples of blood , spleen , liver , kidney , lung , heart , muscle , brain , fat , and tumor were removed and the radioactivity counted . - pubmed
Autoradiographic images of mice injected with PG -[ 3H ] TXL revealed that radioactivity was primarily located in the periphery of the tumor on day 1 after drug administration and was homogeneously diffused into the center of the tumor by day 6 . - pubmed
Patients received an intravenous infusion MDXH210 during a period of 2 h three times per week for 2 weeks and were monitored for toxicity . - pubmed
Based on this fact , thrombolysis may represent a new and effective causal therapeutic strategy in patients suffering from cardiac arrest due to acute myocardial infarction or fulminant pulmonary embolism . - pubmed
This effect might be responsible for the exceptionally good neurological outcome observed in patients treated with thrombolytic agents during cardiopulmonary resuscitation and might be a result of the proven imbalance of the endogenous coagulation system in patients suffering from cardiac arrest . - pubmed
This coagulation imbalance is thought to be responsible for postresuscitation cerebral microcirculatory reperfusion disorders in patients after cardiac arrest and cardiopulmonary resuscitation . - pubmed
and Salmonella enterica is a significant source of human diarrheal disease . - pubmed
DESIGN : Telephone questionnaire of 50 patients who attended A & amp ; E in 1998 with diagnosis of Colles fracture SETTING : Glasgow Royal Infirmary within North Glasgow catchment area . - pubmed
The enigma of occult mitral regurgitation in a patient with cardiogenic shock . - pubmed
In patients with mitral regurgitation ( MR ) , there is a high pressure gradient between the left ventricle ( LV ) and left atrium that Doppler echocardiography can easily detect . - pubmed
We present a case where transthoracic echocardiography ( TTE ) failed to provide an accurate evaluation of a patient who presented in cardiogenic shock . - pubmed
In addition , ADM plasma concentrations in breast cancer patients and healthy controls were determined by radioimmunoassay . - pubmed
Investigations into an outbreak of tuberculosis in a flock of sheep in contact with tuberculous cattle . - pubmed
Tuberculosis , associated with Mycobacterium bovis infection , occurs infrequently in sheep . - pubmed
A sheep flock , which was potentially exposed to a high level of infection from in - contact tuberculous cattle , was examined for evidence of infection . - pubmed
Tuberculous lesions were present in four of these sheep . - pubmed
This paper describes the first report of an outbreak of tuberculosis in sheep in either Britain or Ireland . - pubmed
Estimates of test characteristics were obtained for 60 consecutive patients with an anterior ankle impingement syndrome . - pubmed
These results suggest the possibility that treatment with estradiol under low - calcium conditions can not improve impaired learning and memory when progesterone is applied simultaneously , and that the intake of adequate calcium may be necessary and effective for patients with learning and memory hypofunction receiving hormone replacement therapy . - pubmed
Excessive daytime somnolence in Japanese patients with Parkinson ' s disease . - pubmed
To investigate the prevalence and severity of excessive daytime somnolence ( EDS ) in Japanese patients with Parkinson ' s disease ( PD ) and to examine the main cause of EDS . - pubmed
Fifty - three Japanese patients with PD ( PDs : 32 females and 21 males ) and 17 controls ( 10 females and seven males ) were evaluated using the Epworth Sleepiness Scale ( ESS ) . - pubmed
Metastatic spine tumors affect a large number of patients each year , resulting in significant pain , destruction of the spinal column causing mechanical instability , and neurologic deficits . - pubmed
In addition , cancer patients may have difficulty with access to a radiation treatment facility for prolonged daily fractionated therapy . - pubmed
CyberKnife spinal radiosurgery offers a new and important alternative therapeutic modality for the treatment of spinal metastases in medically inoperable patients , previously irradiated sites , and for lesions not amenable to open surgical techniques or as an adjunct to surgery . - pubmed
Spinal radiosurgery is likely to become an essential part of any neurosurgical spine center that treats a large number of patients with spinal metastases . - pubmed
The analysis of gray matter structure and connecting white matter paths combined with the ability to bring all information into a common space via intersubject registration should provide us with a rich set of data to investigate structure and variation in the human brain in neuropsychiatric disorders , as well as provide a basis for current work in the development of integrated brain function - structure analysis . - pubmed
Historically , the medical profession has been successful in treating most bacterial infections in humans with synthetic second- and third - generation antibiotics . - pubmed
Infections caused by the Gram - negative bacteria Pseudomonas aeruginosa and Acinetobacter spp . - pubmed
OBJECTIVE : To evaluate whether inpatient services within an academic setting were achieving / addressing primary and secondary lipid goals in patients with established CAD or CVD . - pubmed
The proteomic approach presented here may have broad applications for rapid proteomic analyses of various mouse models of human brain diseases . - pubmed
glycolicum ( 30.6 % similarity between the proposed type strain of the novel species , WAL 16138 , and C. - pubmed
The type strain of C. - pubmed
Human Trypanosoma cruzi infection and seropositivity in dogs , Mexico . - pubmed
A direct correlation ( r2 = 0.955 ) of seropositivity between humans and dogs suggests that seroanalysis in dogs may help identify the human prevalence of T. - pubmed
BACKGROUND : Currently , no specific immunohistochemical markers are available to differentiate primary mucinous epithelial ovarian cancer ( MOC ) from adenocarcinomas originating at other sites that have metastasised to the ovary , which may have an impact on patient management and prognosis . - pubmed
The efficiency of screening could be improved by limiting screening to diabetic patients not receiving ACE inhibitor / ARB therapy and without known DKD . - pubmed
Seventy individual lumbar sympathetic blocks were performed in 13 patients ( six female , seven male ; mean age , 45 years ) with reflex sympathetic dystrophy of the foot . - pubmed
The question of continuous versus intermittent chemotherapy for patients with metastatic colorectal cancer has been an ongoing issue of debate for determining the optimum duration of treatment . - pubmed
We describe a case of a patient with type 2 diabetic end - stage renal disease ( ESRD ) treated by PD who had new - onset dyspnea , right pleural effusion , and uncontrolled hyperglycemia . - pubmed
[ Characteristics of blood aggregation in human subjects of different age categories during normobaric interval hypo - oxytraining ] . - pubmed
Blood aggregation was studied in human subjects of different age groups given normobaric hypooxytraining . - pubmed
The experiment was performed with participation of two groups of volunteers : experienced human subjects well - adapted to hypoxia and young non - adapted subjects . - pubmed
Two groups of the human subjects displayed significantly different reactions to of blood aggregation to the extreme factor ( NOT ) . - pubmed
Interdisciplinary rehabilitation of a patient with Opitz C - syndrome and extensive craniofacial malformation . - pubmed
Time trends and risk factors for diabetes mellitus in cats presented to veterinary teaching hospitals . - pubmed
Low intervertebral disc height in postmenopausal women with osteoporotic vertebral fractures compared to hormone - treated and untreated postmenopausal women and premenopausal women without fractures . - pubmed
OBJECTIVE : To assess the intervertebral disc height in postmenopausal women with osteoporotic vertebral fractures . - pubmed
The disc height of the group of women ( n = 38 ) with osteoporotic vertebral fractures was compared to the disc heights of hormone - treated women ( n = 47 ) , untreated postmenopausal women ( n = 77 ) and another group of premenopausal women ( n = 41 ) . - pubmed
METHODS : From January 2001 to December 2005 , 17 HIV patients , with at least one previous episode of VL who received L - AMB as secondary prophylaxis for VL , were included in the study . - pubmed
Efficacy was measured as the proportion of patients remaining free ( non - relapse ) of VL at different time points . - pubmed
Prophylaxis with L - AMB was well tolerated and only three patients had a mild impairment of renal function without requiring any change in treatment . - pubmed
[ Comment on " Automated perimetry in patients with primary congenital glaucoma " ] . - pubmed
We report a 17 - year - old boy who was diagnosed as autoimmune encephalitis with various neurological complications such as hemiplegia , aphasia and seizures . - pubmed
We demonstrated the possibility of steroid - sparing treatment with tacrolimus for a patient with steroid - responsive encephalitis . - pubmed
Tacrolimus may be effective for selected patients with recurrent encephalitis in which an autoimmune mechanism is considered as the pathogenesis . - pubmed
Fifteen years after transplantation , the patient presented with variceal bleeding , liver biopsy showed nodular regenerative hyperplasia ( NRH ) . - pubmed
Furthermore , a high index of suspicion with early detection of NRH is crucial , as improvement seems only to occur in patients with compensated liver disease . - pubmed
Inactivation of malignant tissue in tumor - immune rats . - pubmed
PATIENTS AND METHODS : Charts of patients treated from January 2004 to January 2006 were reviewed for choice of treatment , tumor response , toxicities and survival . - pubmed
Early interruption of treatment due to toxicity or patient 's refusal ( 42.5 vs. 15.6 , p=0.001 ) and deaths within 30 days from last chemotherapy administration ( 22.5 % vs. 3.9 % , p=0.003 ) were significantly different . - pubmed
F patients may respond to chemotherapy but display higher rates of premature withdrawal and early deaths compared to NF patients , with a shorter survival . - pubmed
Sixty consecutive patients suffering epistaxis of local origin in an Accident and Emergency department in a District General Hospital were included in this study which was conducted over a 7 - month - period ( September - March ) . - pubmed
Data collected included : patient 's demographics , cause of epistaxis , management plan , admission , in - patient stay and complications . - pubmed
In the patients ' group treated under the revised protocol , the total number of admissions was significantly reduced , by 73 % , ( P & lt ; 0.0001 ) , despite no significant change in the number of monthly epistaxis referrals ( P & lt ; 0.0001 ) . - pubmed
There was also a significant increase in the mean age of admitted patients with epistaxis ( P & lt ; 0.0001 ) , the admitted patients had a mean length of stay of 2.5 days . - pubmed
RESULTS : We recorded 169 UTI in 76 patients ( 38 men/38 women , 33 % ) over a mean follow - up of 779.9+/-523.3 days . - pubmed
OBJECTIVE : The aim of this study was to find an effective treatment for the genetic form of diabetes that is present in some Huntington ' s disease patients and in Huntington ' s disease mouse models . - pubmed
The treatment also improved motor function and extended the survival time of the Huntington ' s disease mice . - pubmed
We studied 192 postmenopausal women with low BMD with a mean age of 62.75 + /- 8.58 years . - pubmed
Prevelance of CD in postmenopausal women with low BMD ( 0.5 % ) did not differ from prevelance of CD in normal healthy population ( 0.3 - 1 % ) . - pubmed
Advantages of delaying the onset of rehabilitative reaching training in rats with incomplete spinal cord injury . - pubmed
We have previously reported that rehabilitative reaching training initiated 4 days following an incomplete cervical spinal cord injury ( SCI ) in adult rats promotes plasticity and task - specific recovery . - pubmed
The effects of psychological status of the patients with digestive system cancers on prognosis of the disease . - pubmed
To assess the association between psychological status and prognosis of patients with digestive system cancer , epidemiological investigations were conducted in 2 periods to obtain information about the patients ' psychological status , survival time , and quality of life . - pubmed
Despite important gaps in our knowledge regarding how phytochemicals interfere with cellular function in vivo , effective chemopreventive measures have shown that phytochemicals can be utilized to prevent cancer , and possibly to treat cancer patients as well . - pubmed
PATIENTS AND METHODS : Among the patients with genetically determined enzymopathies 3 patients had aminoacidopathies , and 11 had different types of encephalopathies , from which 10 had mitochondrial encephalomyopathy ( MEMP ) , and 1 patient had hyperuricaemic encephalopathy . - pubmed
Besides the mentioned 14 patients , 1 had ceroid lipofuscinosis and another patient had tuberous sclerosis . - pubmed
Mitochondrial encephalo - myopathic ( MEMP ) group -- all the four patients with MEMP and lactic acidosis showed focal hypoperfusion in the temporal region , while the perfusion was normal in the COX deficient patient and in 2 Leigh ' s disease ( subacute necrotizing encephalopathy ) patients . - pubmed
In the remaining 1 Leigh 's patient frontotemporal hypoperfusion was found . - pubmed
In all patients there were non specific structural abnormalities detected by MRI : cortical and subcortical atrophy , and scattered demyelination foci . - pubmed
The patient with tuberous sclerosis showed bilateral temporo - occipital hypoperfusion . - pubmed
In the present article , we review the putative effects of insulin resistance on EPCs , discuss the underlying mechanisms and highlight potential therapeutic manoeuvres which could improve vascular repair in individuals with insulin resistance . - pubmed
Unlike human blood monocytes , these melanoma cells require no exogenous stimulation . - pubmed
Patients were randomized either to primary ( p - PCI ) or to full - dose tenecteplase before PCI ( f - PCI).The study end point was the composite of death , cardiogenic shock , or congestive heart failure at 90 days . - pubmed
A study to determine the seroprevalence of Dirofilaria immitis was carried out in feral cats in Grenada . - pubmed
immitis infection in feral cats coupled with the endemic nature of heartworm disease in dogs in Grenada leads us to suggest the introduction of heartworm prophylaxis in cats . - pubmed
CLINICAL PRESENTATION : A 45 - year - old man presented to our institution with subarachnoid hemorrhage secondary to a small distal basilar trunk aneurysm . - pubmed
We report a case of ipsilateral combination of Galeazzi and Monteggia fractures in a ten - year - old patient . - pubmed
RESULTS : The group included 41 boys , 60 % with coronal or distal hypospadias and 40 % with mid - shaft hypospadias ( aged 6 months to 16 years , median : 3 years ) . - pubmed
A 6 - year - old boy presented with a diffuse mediastinal mass and received an open mediastinal biopsy for a definitive diagnosis , which led to the occurrence of massive chylothorax postoperatively . - pubmed
Tympanic membrane wound healing in rats assessed by transcriptome profiling . - pubmed
Subsequent analysis was performed using Agilent 's 4 x 44 k whole rat genome arrays ( 40 in total ) to assess wound - healing gene expression over a 7 - day time period . - pubmed
Solithromycin demonstrated potent in vitro activity against the NF54 strain of P. - pubmed
berghei infection in mice , solithromycin demonstrated a 100 % cure rate when administered as a dosage regimen of four doses of 100 mg / kg of body weight , the same dose required for artesunate or chloroquine to achieve 100 % cure rates in this rodent malaria model . - pubmed
Dovyalis abyssinica might be a promising candidate for phytotherapy of trypanosomiasis . - pubmed
Patient preferences for coronary artery bypass graft surgery or percutaneous intervention in multivessel coronary artery disease . - pubmed
OBJECTIVES : Determine if patients prefer multivessel percutaneous coronary intervention ( mv - PCI ) over coronary artery bypass graft surgery ( CABG ) for treatment of symptomatic multivessel coronary artery disease ( mv - CAD ) despite high 1 - year risk . - pubmed
BACKGROUND : Patient risk perception and preference for CABG or mv - PCI to treat medically refractory mv - CAD are poorly understood . - pubmed
METHODS : 585 patients and 31 physicians were presented standardized questionnaires with a hypothetical scenario describing chest pain and medically refractory mv - CAD . - pubmed
A 22 - year - old woman with features suggestive of Cushing ' s syndrome was found to have right adrenal mass on imaging studies . - pubmed
Black adenoma of the right adrenal cortex , a pigmented adenoma consisting of compact cells with numerous pigments suggestive of melanin and lipofuscin was laproscopically removed from this patient . - pubmed
We report on the case of a patient developing biliary tract obstruction due to fibrous material in the common hepatic duct 15 years after pancreatoduodenectomy . - pubmed
The dengue human challenge model : has the time come to accept this challenge ? - pubmed
Certain N -( naphthalen-2 - yl ) acetamide and N -( substituted phenyl ) acetamide bearing quinolin-2 ( 1H )- one and 3,4 - dihydroquinolin-2 ( 1H )- one derivatives have been synthesized and evaluated in vitro for their antiproliferative activities against a panel of human cancer cell lines including nasopharyngeal ( NPC - TW01 ) , lung carcinoma ( H661 ) , hepatoma ( Hep3B ) , renal carcinoma ( A498 ) , and gastric cancer ( MKN45 ) . - pubmed
In addition , compound 18 demonstrated very specific cytotoxicity against human nasopharyngeal carcinoma ( NPC - TW01 ) cell lines with no detectable cytotoxicity against peripheral blood mononuclear cells ( PBMCs ) at a concentration of up to 50 muM. - pubmed
An opportunity for cancer prevention during preadolescence and adolescence : stopping human papillomavirus ( HPV )- related cancer through HPV vaccination . - pubmed
CONCLUSIONS : The results suggest that healthcare providers in rural areas can increase HPV vaccine uptake and reduce HPV - related cancers by using a multifaceted approach to educating their patients within the context of the patients ' cultural values , geographic location , and economic situation . - pubmed
Bariatric surgery has to be considered in the management of severely obese adolescents when all conservative measures have been proven to be unresponsive . - pubmed
Fiveteen years old girl with body mass index 42.2 kg / m(2 ) , hyperinsulinism , hyperandrogenism , amenorrhea , polycystic ovarian syndrome , hypertension with left ventricular hypertrophy . - pubmed
We can conclude that bariatric surgery should be considered for a minority of severely obese adolescents under the supervision of a multidisciplinary pediatric team . - pubmed
The increased surgical accuracy in robotic assistance could limit postoperative complications rate in obese adolescents . - pubmed
METHODS : We report three cases of patients with a bipartite atlas as a coincidental finding in a trauma setting . - pubmed
The patients had no neurological symptoms relating to the C1 abnormality , and no follow - up was performed . - pubmed
Over - aggressive treatment of grade V SAH patients . - pubmed
In patients with operable esophageal cancer , there is evidence supporting the use of preoperative chemotherapy or preoperative chemoradiation . - pubmed
The organism isolated from culture of the biopsy material was Fonsecaea pedrosoi thus confirming our diagnosis of cutaneous chromoblastomycosis . - pubmed
Early changes of gene expression profiles in the rat model of arterial injury . - pubmed
The purpose of the present study was to investigate the early alterations in arterial - wall gene expression after balloon injury in the rat carotid artery with focus on the induction of an inflammatory response . - pubmed
MATERIALS AND METHODS : Twenty - four male Sprague - Dawley rats were subjected to injury of the left common carotid artery by using a 2 - F Fogarty catheter . - pubmed
People with type 2 Diabetes have an elevated risk for developing cardiovascular disease ( CVD ) for which dyslipidemia is the major contributor . - pubmed
Altered autophagy induction by sera from pregnant women with pre - eclampsia : a case - control study . - pubmed
We hypothesised that sera from women with healthy pregnancies and women with pre - eclampsia differed in autophagy induction . - pubmed
POPULATION : Twenty - four normotensive pregnant women and 20 women with pre - eclampsia . - pubmed
RESULTS : Autophagy induction increased with gestational age in sera from normotensive women ( P = 0.0045 ) , but not in women with pre - eclampsia . - pubmed
In the presence of an autophagy inducer , the capacity for autophagy induction decreased with gestational age in sera from women with pre - eclampsia ( P = 0.0235 ) , but not from controls . - pubmed
CONCLUSIONS : Sera from women with pre - eclampsia differ from normotensive women by their inability to induce autophagy as a function of gestational age . - pubmed
Efficacy and safety of mavrilimumab in Japanese subjects with rheumatoid arthritis : findings from a Phase IIa study . - pubmed
Our findings demonstrate that caffeine can be combined with OTP and the absorption of C - CAF is inhibited in mice , thus decreasing the irritation effect of caffeine . - pubmed
Orthosiphon stamineus protects Caenorhabditis elegans against Staphylococcus aureus infection through immunomodulation . - pubmed
CONCLUSION : PTLPs demonstrate capability in eradicating C difficile in vitro , and with further development , may represent an organism - specific , microbiome - sparing therapy for CDI . - pubmed
Renal sparing surgery using focus ultracision harmonic scalpel in patients with bilateral wilms ' tumor : case report . - pubmed
CASE REPORT : We describe a 3 year - old female patient with bilateral Wilms ' tumor arising in the central localisation of the right and foci in the left kidney enucleated successfully with a simple and comfortable renal preserving operative technique using Focus Ultracision Harmonic Scalpel . - pubmed
A total of 24 RTT patients were assigned to omega-3 PUFAs - containing fish oil for 12 months in a randomized controlled study ( average DHA and EPA doses of 72.9 , and 117.1mg / kgb.w./day , respectively ) . - pubmed
OBJECTIVES : The goal of this study was to compare cardiac output derived from the FloTrac / Vigileo system ( CO(FT ) ) with cardiac output measured by 3 - dimensional transesophageal echocardiography ( CO3D ) in patients with severe heart failure undergoing cardiac resynchronization therapy . - pubmed
CONCLUSIONS : The FloTrac / Vigileo system is not accurate in patients with low cardiac output , especially those with a cardiac index<2.2 L / min / m(2 ) . - pubmed
A total of 166 D - IBS patients were randomly divided into four treatment groups , which included each combination of the examined frequencies and doses . - pubmed
KIM is being piloted in a clinical trial for prostate cancer patients treated with VMAT ( NCT01742403 ) . - pubmed
EXPERIMENTAL DESIGN : The influence of coffee consumption on patient and tumor characteristics and disease - free survival was assessed in a population - based cohort of 1,090 patients with invasive primary breast cancer in Sweden . - pubmed
[ Efficacy and safety of sugammadex ( Org 25969 ) in reversing deep neuromuscular block induced by rocuronium or vecuronium in Japanese patients ] . - pubmed
BACKGROUND : Efficacy and safety of sugammadex in reversing neuromuscular block induced by rocuronium or vecuronium were investgated in Japanese patients . - pubmed
Twenty - five subjects with T2DM2 , 25 healthy controls , 25 subjects with obesity , and 25 subjects with T2DM combined with obesity were included in the study . - pubmed
RESULTS : 22,305 patients ( 1.5 % ) experienced a UTI . - pubmed
METHODS : The study group comprised 74 middle - aged patients with chronic AKP . - pubmed
Toxicity of synthetic herbicides containing 2,4 - D and MCPA moieties towards Pseudomonas putida mt-2 and its response at the level of membrane fatty acid composition . - pubmed
A 42 - year - old woman was referred , for adjuvant treatment , by an oncosurgeon ( outside our centre ) after a transhiatal oesophagectomy and gastric pull - up for middle one - third squamous cell carcinoma of the oesophagus pT3N1M0 . - pubmed
The patient tolerated the treatment well and had partial pain relief , and , in view of poor prognosis , was advised best supportive care . - pubmed
Transplantation of Encapsulated Pancreatic Islets as a Treatment for Patients with Type 1 Diabetes Mellitus . - pubmed
This review consists of three sections : introduction to islet transplantation , transplantation of encapsulated pancreatic islets as a treatment for patients with type 1 diabetes mellitus ( T1DM ) , and present challenges and future perspectives . - pubmed
PURPOSE : This paper aimed to report a case of Brown - Sequard - plus syndrome in an 8 - year - old boy secondary to a scissors stab wound at the craniocervical junction . - pubmed
METHODS : The case study of an 8 - year - old boy who was hospitalized because of a scissors stab wound at the craniocervical junction . - pubmed
The patient developed Brown - Sequard - plus syndrome on the left side of the body . - pubmed
Influenza infection in human host : challenges in making a better influenza vaccine . - pubmed
Human Bite - induced Cellulitis Due to Streptococcus pyogenes . - pubmed
The rate of infection after a human bite is 10%-30 % . - pubmed
The authors describe a 5 - year - old girl admitted to the emergency room with cellulitis due to S. - pubmed
pyogenes after human bites . - pubmed
She presented with fever and pain in her left arm , and her medical history revealed a human bite by her cousin on the arm 3 days prior . - pubmed
pyogenes may cause serious wound infections following human bites . - pubmed
This case was first reported as cellulitis due to S. - pubmed
pyogenes after a human bite . - pubmed
The bioartificial ACL graft was subsequently implanted in a swine ACL rupture model in place of the surgically removed normal ACL . - pubmed
Bile deficiency induces changes in intestinal glucose absorption in mice . - pubmed
The poor prognosis for patients with inflammatory breast cancer ( IBC ) compared to patients with other types of breast cancers emphasizes the need to better understand the molecular underpinnings of this disease with the goal of developing effective targeted therapeutics . - pubmed
Diet - induced obesity increases the frequency of Pig - a mutant erythrocytes in male C57BL/6J mice . - pubmed
Obesity increases the risk of a number of chronic diseases in humans including several cancers . - pubmed
Pig - a mutant frequencies and micronucleus frequencies were determined in blood cells in two independent experiments in 30 - week old male mice reared on either a high - fat diet ( 60 % calories from fat ) that exhibit an obese phenotype or a normal - fat diet ( 10 % calories from fat ) that do not exhibit an obese phenotype . - pubmed
Lymphoepithelioma - like carcinoma of breast - evaluation for Epstein - Barr virus - encoded RNA , human papillomavirus , and markers of basal cell differentiation . - pubmed
Analysis for in situ hybridization for Epstein - Barr virus - encoded RNAs and human papillomavirus DNA on paraffin - processed tissues was negative in all tumors . - pubmed
RESULT : Of the 39/252 ( 15.4 % ) ELBW infants who developed IH , those with early ( 59 % ) versus late ( 41 % ) repair were comparable in birth weight ( 753 + - 158 versus 744 + - 131 g , p = 0.84 ) , gestation age ( 26 + - 2 versus 26.2 + - 2 weeks , p = 0.92 ) , with comparable rate of broncopulmonary dysplasia ( 87 % versus 75 % , p = 0.41 ) , but early repair group had prolonged respiratory support ( 60.6 + - 28.6 versus 39 + - 30 days , p = 0.032 ) . - pubmed
A Comparative Approach of Tumor - Associated Inflammation in Mammary Cancer between Humans and Dogs . - pubmed
It has been well established that the development of mammary cancer , both in humans and in dogs , is associated with alterations in numbers and functions of immune cells at the sites of tumor progression . - pubmed
Indeed , recent studies in human breast cancer and in canine mammary tumors have identified a growing list of signaling molecules released by inflammatory cells that serve as effectors of their tumor - promoting actions . - pubmed
This review describes the intertwined signaling pathways shared by T - lymphocytic / macrophage infiltrates and important tissue biomarkers in both human and dog mammary carcinogenesis . - pubmed
We previously observed an increase in arrhythmias during spontaneous prolonged hypoglycemia in patients with T2DM . - pubmed
Participants with T2DM exhibited greater heterogeneity of repolarization during hypoglycemia as demonstrated by T - wave symmetry and principal component analysis ratio compared with control participants . - pubmed
Individuals with T2DM demonstrate greater repolarization abnormalities for a given hypoglycemic stimulus despite comparable sympathoadrenal responses . - pubmed
METHODS : Thirty - eight patients with a major depressive disorder ( MDD ) and forty healthy matched controls were assessed with a ToM task using animated triangles . - pubmed
RESULTS : Our findings show that 1 ) healthy female controls performed significantly stronger on the ToM task than female MDD patients , 2 ) these performance differences were driven by attachment styles and 3 ) depression severity did not impact task performance . - pubmed
Here , we describe establishment of a human ovarian carcinoma cell line , which we term WHIRC01 , from a patient - derived mouse xenograft established from a chemorefractory HGSOC patient who did not respond to carboplatin and paclitaxel therapy . - pubmed
WHIRC01 represents a chemorefractory human HGSOC cell line model with a comprehensive molecular profile to aid future investigations of drug resistance mechanisms and screening of chemotherapeutic agents . - pubmed
Moreover , mice infected with the TgCDS1 mutant became fully resistant to challenge infection with a hyper - virulent strain of T. - pubmed
aureus ( MRSA ) ; however , the commonly used drug amoxicillin / clavulanic acid was effective only against sensitive strains . - pubmed
Here , we report the case of a 2 - year - old child who presented with severe nutritional rickets associated with seizure and cardiomyopathy . - pubmed
We present a case of herpes zoster eruption occurring after PDT for actinic keratoses in a patient with Non - Hodgkin Lymphoma ( NHL).</p> ; & lt;p><em>J Drugs Dermatol . - pubmed
Patients : Adults aged 45 years or older who had or were at risk for atherosclerotic disease and were having noncardiac surgery . - pubmed
Results : In patients with prior PCI , aspirin reduced the risk for the primary outcome ( absolute risk reduction , 5.5 % [ 95 % CI , 0.4 % to 10.5 % ] ; hazard ratio [ HR ] , 0.50 [ CI , 0.26 to 0.95 ] ; P for interaction = 0.036 ) and for myocardial infarction ( absolute risk reduction , 5.9 % [ CI , 1.0 % to 10.8 % ] ; HR , 0.44 [ CI , 0.22 to 0.87 ] ; P for interaction = 0.021 ) . - pubmed
The effect on the composite of major and life - threatening bleeding in patients with prior PCI was uncertain ( absolute risk increase , 1.3 % [ CI , -2.6 % to 5.2 % ] ) . - pubmed
Objectives : Cervical nerves block can not be performed on some patients because of the risk of phrenic nerve paralysis . - pubmed
Case report : We present the case of a 62 - year - old woman with clavicular fracture . - pubmed
Conclusions : We can perform selective supraclavicular nerve blocks for clavicular fracture surgery of patients who have bilateral pneumothorax . - pubmed
Finally , the implications of these processes in developing strategies to prolong the cancer - free human lifespan are discussed . - pubmed
The Potential Effects of New Stent Platforms for Coronary Revascularization in Patients With Diabetes . - pubmed
Coronary artery disease in patients with diabetes mellitus ( DM ) is characterized by extensive atherosclerosis , longer lesions , and diffuse distal disease . - pubmed
Traditionally , coronary artery bypass grafting ( CABG ) has been regarded as more effective than percutaneous coronary intervention ( PCI ) in patients with DM , likely because of more complete revascularization and protection against disease progression in the bypass segment . - pubmed
Revascularization with balloon angioplasty , bare - metal stents , and first - generation drug - eluting stents have all been shown to be inferior to CABG in patients with DM . - pubmed
The use of thinner struts , biocompatible polymer coating , and newer antiproliferative agents have improved the rates of cardiovascular events in patients with DM revascularized percutaneously . - pubmed
Since the publication of current guidelines , new studies suggested acceptable outcomes in patients with DM revascularized with second - generation drug - eluting stents , even though these conclusions are drawn from small subgroup analyses or nonrandomized studies . - pubmed
Therefore , contemporary revascularization in patients with DM with multivessel coronary artery disease should involve a multidisciplinary approach , in which interventional cardiologists and cardiac surgeons involve their patients to individualize treatment choices , and balance the risks and effectiveness of each modality . - pubmed
Cardiovascular phenotype and prognosis of patients with heart failure induced by cancer therapy . - pubmed
OBJECTIVE : This study compared the clinical features , cardiac structure and function evaluated by echocardiography , cardiopulmonary response to exercise and long - term clinical outcomes between patients with heart failure ( HF ) induced by cancer therapy ( CTHF ) and heart failure not induced by cancer therapy ( NCTHF ) . - pubmed
METHODS : We evaluated 75 patients with CTHF and 894 with NCTHF who underwent clinically indicated cardiopulmonary exercise testing , and followed these individuals for a median of 4.5 ( 3.0 - 5.8 ) years , during which 187 deaths and 256 composite events ( death , heart transplantation and left ventricular ( LV ) assistant device implantation ) occurred . - pubmed
RESULTS : Compared with NCTHF , patients with CTHF were younger , with lower prevalence of cardiovascular comorbidities , higher LV ejection fraction ( LVEF ) , but similar global longitudinal strain . - pubmed
Autophagy induced by ionizing radiation promotes cell death over survival in human colorectal cancer cells . - pubmed
Reduced activity and connectivity of left amygdala in patients with schizophrenia treated with clozapine or olanzapine . - pubmed
Obsessive - compulsive symptoms ( OCS ) in patients with schizophrenia are a common co - occurring condition , often associated with additional impairments . - pubmed
A subgroup of these patients develops OCS during treatment with second - generation antipsychotics ( SGAs ) , most importantly clozapine and olanzapine . - pubmed
Effect of progesterone administration on the prognosis of patients with severe traumatic brain injury : a meta - analysis of randomized clinical trials . - pubmed
Methods : A systematic literature search of PubMed , Embase , and Cochrane databases and the Web of Science ( from establishment of each to September 1 , 2018 ) was performed to identify original RCTs that evaluated the associations between progesterone treatment and the prognosis of patients with severe TBI . - pubmed
Results : Eight RCTs enrolling 2,251 patients with severe TBI were included . - pubmed
METHODS : A prospective cohort study of 106 patients who were switched to this dual regimen from April 2014 to December 2017 because of renal and bone toxicity , intolerance , or physician 's decision was conducted . - pubmed
Six patients presented with metastatic foci ( five to the liver and one to the lung ) , while lymphadenopathy was observed in five patients ( 20 % ) . - pubmed
Impact of pre - existing dengue immunity on human antibody and memory B cell responses to Zika . - pubmed
Little is known about enduring memory B cell ( MBC ) responses to Zika virus ( ZIKV ) and their relationship with circulating antibodies . - pubmed
Here we comprehensively assess MBC frequency and specificity alongside serum binding and neutralizing antibody responses to ZIKV ~2 weeks and ~8 months postinfection in 31 pediatric subjects with 0 , 1 or & gt;1 prior infections with the related dengue virus ( DENV ) . - pubmed
ZIKV infection elicits a robust type - specific MBC response , and the majority of late convalescent anti - ZIKV serum neutralizing activity is attributable to ZIKV - specific antibodies . - pubmed
The number of prior DENV infections does not influence type - specific or cross - reactive MBC responses , although ZIKV has the highest cross - reactivity with DENV3 . - pubmed
BACKGROUND : Treatment adherence and persistence are crucial to achieve glycemic control in patients with type 2 diabetes ( T2D ) . - pubmed
Changes in A1c and body weight from baseline through 6 months were assessed for all patients ; early response was defined by & gt ; 1 % reduction in A1c and & gt ; 3 % reduction in body weight within 3 - 6 months . - pubmed
RESULTS : Among 8,329 identified patients , 33.3 % and 31.2 % experienced early response as indicated by reductions in A1c & gt ; 1 % point and in body weight & gt ; 3 % from baseline , respectively . - pubmed
Significantly higher proportions ( P & lt ; 0.001 ) of early responders in both reduced A1c and body weight were adherent over 18 months compared with patients without an early response ( A1c : 45.0 % vs. 37.1 % ; body weight : 43.3 % vs. 38.0 % ) . - pubmed
Significantly lower proportions ( P & lt ; 0.001 ) of early responders discontinued over 18 months compared with patients without an early response ( A1c : 61.4 % vs. 67.9 % ; body weight : 61.9 % vs. 67.5 % ) . - pubmed
Glyphosate , a widely used herbicide , has been classified as probably carcinogenic to humans by the International Agency for Research on Cancer ( IARC ) . - pubmed
These patients have pituitary adenomas that are thought to be mixed lactotrophs and somatotrophs . - pubmed
CASE DESCRIPTION : The patient 's mother , diagnosed with acrogigantism at 21 months , underwent pituitary tumor excision at 24 months . - pubmed
The pathophysiological mechanisms of cognitive and gait disturbances in subjects with normal - pressure hydrocephalus ( NPH ) are still unclear . - pubmed
Cholinergic and other neurotransmitter abnormalities have been reported in animal models of NPH . - pubmed
The objective of this study was to evaluate the short latency afferent inhibition ( SAI ) , a transcranial magnetic stimulation protocol which gives the possibility to test an inhibitory cholinergic circuit in the human brain , in subjects with idiopathic NPH ( iNPH ) . - pubmed
We applied SAI technique in twenty iNPH patients before ventricular shunt surgery . - pubmed
A significant reduction of the SAI ( p = 0.016 ) , associated with a less pronounced decrease of the resting motor threshold and the short latency intracortical inhibition to paired stimulation , were observed in patients with iNPH at baseline evaluation . - pubmed
These findings suggest that the impairment of cholinergic neurons markedly contributes to cognitive decline and gait impairment in subjects with iNPH . - pubmed
A prolific biofilm forming strain ( Staphylococcus lentus ) , possessing high tolerance ( > 1,000 microg ml-1 ) to dissolved copper ions ( Cu ++ ) was isolated from titanium coupons exposed in the coastal waters of Kalpakkam , east coast of India . - pubmed
It is defined as a triad of microangiopathic hemolytic anemia , thrombocytopenia and renal insufficiency associated with Shiga toxin - producing Escherichia coli . - pubmed
Case report : We report the case of a one - year - old Caucasian girl , without significant medical history , who was found to have stool culture with positive enteropathogenic Escherichia coli after an episode of diarrhea . - pubmed
The role of structured physiotherapy in treating patients with atraumatic shoulder instability : Medium term results from a case series . - pubmed
Patients with posterior instability demonstrated better results compared with other groups ( OSIS change , p = 0.025 ; WOSI change , p = 0.060 ) . - pubmed
Vitamin D deficiency is common in patients with primary hyperparathyroidism . - pubmed
Comparison of melphalan- And busulfan - based myeloablative conditioning in children undergoing allogeneic transplantation for acute myeloid leukemia or myelodysplasia . - pubmed
BACKGROUND : The optimal conditioning regimen for alloHCT in children with myeloid malignancies remains undefined . - pubmed
PROCEDURE : We performed a retrospective review of children undergoing alloHCT for AML and MDS over a 10 - year period ( 2008 - 2018 ) at our institution , comparing the outcomes of recipients of either a myeloablative busulfan- or reduced toxicity mel / thio - based conditioning regimen . - pubmed
RESULTS : A total of 49 patients underwent alloHCT for AML / MDS ( mel / thio , N = 21 ; busulfan , N = 28 ) . - pubmed
One patient in each group died from TRM . - pubmed
Relapse incidence was comparable ( mel / thio-29 % vs busulfan-32 % ) ; however , relapse occurred significantly later in recipients of mel / thio conditioning ( median d + 396 vs d + 137 ; P = .01 ) . - pubmed
CONCLUSION : In our single institution , when compared to myeloablative busulfan - based conditioning , use of a mel / thio - based reduced toxicity regimen resulted in comparable outcomes , despite higher risk patient and disease characteristics . - pubmed
Forty - five patients received > = 1 doses of losatuxizumab vedotin ( 13 colon , 6 non - small cell lung cancer , 5 head and neck [ HNC ] , 5 glioblastoma multiforme , 2 breast , 14 other ) . - pubmed
Multivessel versus culprit - only PCI in STEMI patients with multivessel disease : meta - analysis of randomized controlled trials . - pubmed
AIMS : To perform a pairwise meta - analysis of randomized controlled trials ( RCTs ) comparing multivessel percutaneous coronary intervention ( PCI ) and culprit vessel - only PCI in ST - elevation myocardial infarction ( STEMI ) patients without cardiogenic shock . - pubmed
METHODS : We searched MEDLINE , Cochrane Central Register of Controlled Trials , and Embase for RCTs comparing multivessel PCI with culprit vessel - only PCI in STEMI patients without cardiogenic shock and multivessel coronary artery disease . - pubmed
In total , 523 ( 8.3 % ) of 6314 patients suffered the combined primary endpoint of death or non - fatal reinfarction . - pubmed
CONCLUSIONS : In STEMI patients without cardiogenic shock multivessel PCI reduced the risk of death or non - fatal reinfarction compared to culprit vessel - only PCI . - pubmed
No cytotoxicity is found for cubic and spherical hydrogels upon their interactions with human cancer cells for various time intervals . - pubmed
METHODS : The 98 patients with leukemia in our hospital were divided into two groups according to the diagnosis of patients : ALL group ( 56 cases ) and ANLL group ( 42 cases ) . - pubmed
The related risk factors ( all P<0.05 ) influencing the survival of patients with ALL were confirmed by multivariate logistic analysis . - pubmed
Disrupted potassium ion homeostasis in ciliary muscle in negative lens - induced myopia in Guinea pigs . - pubmed
In the present study , right eyes of the animals in LIM group were covered with -6.0 D lenses to induce myopia . - pubmed
Although not confined to patients who are in their first or second decades of life , ameloblastic fibromas most often arise in this population . - pubmed
CLINICAL SIGNIFICANCE : We might be missing early diagnosis of ameloblastic fibroma and other significant orofacial neoplasms in patients who are nonverbal or nondescriptive such as those with autism . - pubmed
Reader response : Outcomes of patients with stroke treated with thrombolysis according to prestroke Rankin Scale scores . - pubmed
Exploration of biomarkers to predict clinical improvement of atopic dermatitis in patients treated with dupilumab : A study protocol . - pubmed
However , no blood / serum biomarkers are known to predict good or poor outcome in patients with AD treated with dupilumab . - pubmed
METHODS : Patients are at least 18 years of age and have moderate - to - severe AD with Eczema Area and Severity Index ( EASI ) > = 16 , Investigator 's Global Assessment > =3 , and body surface area > = 10 % . - pubmed
Comparison of the efficacy and safety of biological agents in patients with systemic juvenile idiopathic arthritis : A Bayesian network meta - analysis of randomized controlled trials . - pubmed
OBJECTIVE : To assess the relative efficacy and safety of biological agents in patients with systemic juvenile idiopathic arthritis ( sJIA ) . - pubmed
MATERIALS AND METHODS : We performed a Bayesian network meta - analysis to combine direct and indirect evidence from randomized controlled trials ( RCTs ) to examine the efficacy and safety of canakinumab , anakinra , tocilizumab , and rilonacept in patients with sJIA . - pubmed
Biopsy specimens of patients undergoing epilepsy surgery for seizure relief provide unique insights into the impact of promoter SNPs on corresponding mRNA expression . - pubmed
The present data suggest systematic analyses in human hippocampal tissue as a useful approach to unravel the impact of epilepsy candidate SNPs on associated gene expression . - pubmed
To investigate the effects of dietary isomaltooligosaccharide ( IMO ) levels on the gut microbiota , immune function of sows , and the diarrhea rate of their offspring , 120 multiparous gestating pig improvement company ( PIC ) sows with similar body conditions were selected and fed 1 of 6 diets : a basal diet with no supplement ( control , CON ) , or a diet supplemented with 2.5 g / kg , 5.0 g / kg , 10.0 g / kg , 20.0 g / kg , or 40.0 g / kg IMO ( IMO1 , IMO2 , IMO3 , IMO4 , or IMO5 group , respectively ) . - pubmed
METHODS : Medical records of children referred for primary headache to the pediatric neurology clinic at Bnai Zion Medical Center from 2008 to 2017 were assessed . - pubmed
Children in the migraine group used more analgesic treatments to stop the headache attacks compared with the tension - type headache group ( 50 % vs 38 % , P = .001 ) . - pubmed
Patients diagnosed with tension - type headache reported having more emotional difficulties ( P = .001 ) . - pubmed
No significant differences were found in headache characteristics ( ie , location , sidedness , character ) , frequency , or intensity between the younger children ( ages 6 - 11 ) and the adolescents ( ages 12 - 18 ) within either the tension - type headache or migraine groups . - pubmed
METHODS : Fifty - four adults with gingivitis / periodontitis were randomly assigned to 1X ST266 or diluted 0.3X ST266 or saline topically applied on facial / lingual gingiva ( 20muL / tooth ) . - pubmed
CONCLUSIONS : In this " first in human oral cavity " study , topical ST266 was safe and effective in reducing gingival inflammation in 6 weeks . - pubmed
Pathogenetic role of no - reflow phenomenon in experimental subarachnoid hemorrhage in dogs . - pubmed
To study this problem , we carried out the following experiment in dogs : SAH was induced by withdrawing a needle previously inserted into the internal carotid artery through a small craniectomy in the lateral base of the skull . - pubmed
The 32 episodes of SAH thus induced yielded two basic patterns of ICP changes which simulated those previously reported with human SAH . - pubmed
Mouse profile and dog emesis screens were performed , and the activity of various N - substituted derivatives and their esters was evaluated and compared to the parent compounds . - pubmed
[ Lethal infection with BCG in thymectomized mice ] . - pubmed
Investigations carried out on CBA mice demonstrated that adult mice to which mycobacteria BCG were injected intravenously 12 months after thymectomy ( in a dose of 2 mg for a period of 2 1/2 months ) died of disseminated BCG infection against the background of depression of hypersensitivity of delayed type . - pubmed
The chloride - dependent depression by GABA in the frog spinal cord . - pubmed
To evaluate the antihypertensive and hormonal effects of oral magnesium supplementation , 17 inpatients with untreated , uncomplicated mild - to - moderate essential hypertension ( EH ) and 8 age - matched normotensive controls ( controls ) were given MgO orally 3 times a day at a daily dose of 1.0 g ( 0.6 g per day as Mg ) for a period of 2 weeks . - pubmed
suum in their lungs developed more severe pneumonia and septicaemia than did parasite - free mice . - pubmed
multocida as compared with a toxin - producing strain of P. - pubmed
multocida , possibly due to the higher spontaneous pathogenicity of the non - toxigenic strain of P. - pubmed
This paper describes the use of a nasal mask to deliver intermittent positive pressure ventilation to treat chronic respiratory failure in one patient with severe kyphoscoliosis . - pubmed
Intermittent nasal ventilation is a safe and effective ventilatory support modality for some patients with hypercapnic respiratory failure . - pubmed
Intracranial tuberculosis in children : CT appearance and clinical outcome . - pubmed
Of 7 patients with ventriculomegaly , 3 required a ventricular shunt and 2 had spontaneous resolution of ventricular dilatation . - pubmed
Four children with ventriculomegaly were moderately or severely retarded , one had cognitive dysfunction , and one was neurologically normal . - pubmed
Four of six children with tuberculoma also had infarction and/or ventriculomegaly ; of these four children , three were moderately or severely retarded . - pubmed
Two patients with tuberculoma as the only intracranial abnormality had complete resolution of the granuloma with normal neurologic outcome following antituberculous therapy . - pubmed
The four children with large vessel infarction also had ventriculomegaly ; three had poor clinical outcome . - pubmed
The induction of chromosome aberrations in human peripheral blood lymphocytes is still the most useful dosimetry system for accidental whole - body irradiation ; however , in the case of a very large number of casualties the micronuclei technique might provide advantages . - pubmed
Because the National Cholesterol Education Program guidelines suggest that levels of total serum cholesterol less than 5.17 mmol / liter ( 200 mg / dl ) are " desirable , " we performed a retrospective observational analysis to determine the prevalence of coronary artery disease ( CAD ) in patients with total cholesterol less than 5.17 mmol / liter ( 200 mg / dl ) and the prevalence of total cholesterol less than 5.17 mmol / liter ( 200 mg / dl ) in patients with CAD by angiography . - pubmed
Survey of Actinobacillus ( Haemophilus ) pleuropneumoniae infection in swine by different methods . - pubmed
Lung and serum samples from pigs that died or were emergency - slaughtered in a pooled , conventional fattening herd were examined to survey Actinobacillus pleuro - pneumoniae infection and to compare the sensitivity of different testing methods . - pubmed
This study was designed to determine whether blood pressure reduction , per se , causes adverse effects on cognitive and behavioral function in elderly hypertensive patients . - pubmed
Men with mild - to - moderate diastolic hypertension who had passed their 60th birthday were entered into the trial . - pubmed
We conclude that blood pressure reduction , per se , does not adversely affect cognitive and behavioral function in elderly hypertensive patients and that antihypertensive treatment is safe and effective in these patients . - pubmed
Three chromosome - specific repetitive probes labeled with either amino acetyl fluorene ( AAF ) , mercury , or biotin were hybridized simultaneously to metaphase chromosomes prepared from human blood lymphocytes or to interphase tumor nuclei . - pubmed
Three - color in situ hybridization was applied to the study of numerical chromosome abnormalities as occur in human solid tumors . - pubmed
Multifactorial hamster respiratory carcinogenesis with interdependent effects of cannula - induced mucosal wounding , saline , ferric oxide , benzo [ a ] pyrene and N - methyl - N - nitrosourea . - pubmed
Tracheal cancers ( in situ or invasive carcinomas ) were seen only in those hamsters which had received repeated ITC and one or both carcinogens . - pubmed
The cancer latency was shortest and the incidence of tracheal ( 50 % ) and main - stem bronchial ( 21 % ) cancers highest in hamsters given MNU and repeated ITC with BP - Fe2O3 - saline . - pubmed
A group of 250 patients with rheumatoid arthritis were investigated to evaluate the neurologic status with respect to the degree of instability in the proximal cervical spine . - pubmed
Antibodies reactive with heterologous neural tissue were detected by indirect immunofluorescence microscopy in the sera of 17 of 34 patients with retinitis pigmentosa , one of 30 normal control sera , and a variable percentage of sera derived from subjects with diverse ocular and neurological diseases . - pubmed
These antibodies were also found both in disease - free first degree relatives and in spouses of patients with retinitis pigmentosa . - pubmed
Eleven patients with Legg - Calve - Perthes disease ( LCP ) were examined ultrasonographically for their femoral head deformity . - pubmed
However , neither thymic nor other types of leukemias were induced in these rats . - pubmed
Continuous administration of NPU to the rats successfully induced 9 thymic lymphomas in the grafted thymuses . - pubmed
The present results from these 2 experiments strongly suggested that NPU - induced rat thymic lymphomas originate from intrathymic cells but not from bone marrow cells . - pubmed
A previously developed in vitro method using human lymphocytes and a murine microsomal drug metabolizing system has been used to examine toxicity due to acetaminophen ( APAP ) , sulfonamide antibiotics and aromatic anticonvulsants . - pubmed
Lymphocytes from a glutathione synthetase - deficient patient exhibited markedly enhanced toxicity to APAP exceeding the 95 % CL of 10 control subjects over a concentration range of 10 to 1000 micrograms / ml . - pubmed
Experimental lathyrism : exostoses and aneurysmal - like bone cysts of the mandible in the rat . - pubmed
The effect of chronic lathyrism on the mandible of the rat was studied . - pubmed
Histopathology of the experimental cysts had some points in common with the human aneurysmal bone cyst . - pubmed
[ Acute adult leukemia : experience with 41 patients ] . - pubmed
[ Treatment with erythromycin of experimental legionellosis in guinea pigs infected by aerosol ] . - pubmed
The infectious strain L. - pubmed
pneumophila serogroup 1 Philadelphia ( ATCC 33152 ) was cultured on charcoal dialysed yeast extract agar medium ( CDYE agar ) which produces more virulent strains than those grown on classical agar media . - pubmed
Toxicity and mutagenicity tests of 4 anti - cancer drugs in cultured Chinese hamster cells . - pubmed
We describe an elderly woman presenting acutely with tophus formation mimicking infection , in whom diuretic therapy was responsible for her disease . - pubmed
75 % of the patients who developed septicemia within the first three days of life and 60 % of all neonates with septicemia or meningitis could be identified by an elevated I / T - ratio , the most sensitive leukocyte count . - pubmed
Thrombocytopenia was observed in only 33 % of the patients . - pubmed
Pulmonary embolism and deep venous thrombosis in burned patients . - pubmed
The effect and toxicities of Cis - containing combination chemotherapy were tested in 28 patients with primary lung cancer . - pubmed
In addition to these drugs , patients with squamous cell cancer were treated with continuous subcutaneous infusion of 4 mg / m2 Peplomycin for 5 days and one shot i.v . - pubmed
Patients with adeno - and large cell cancer were treated with 30 mg / m2 Adriamycin and 4 mg MMC , while patients with small cell cancer were given 150 mg / m2 VP-16 p.o . - pubmed
Interstitial pneumonitis was observed in 40 % of patients with squamous cell cancer . - pubmed
Two patients with adenocarcinoma died within 3 weeks after treatment due to embolism of the abdominal aorta and myocardial infarction probably caused by treatment with Adriamycin . - pubmed
Investigations were made on 113 patients suffering from CFS . - pubmed
[ Characteristics of the antigenic composition of the cells of intra - and interspecific hybrids of murine hepatoma XXIIa ] . - pubmed
Hybrids of cultivated mouse hepatoma XXIIA cells were studied for the presence of species - specificity antigens . - pubmed
The cells of MGXXIIA hepatoma , clone culture of L mouse fibroblasters and RJK hamster cells were used as parental cells . - pubmed
Bone mineral density in patients with prostatic cancer treated with orchidectomy and with estrogens . - pubmed
The patients were free from metastases during the entire observation period . - pubmed
To study the role of T cells in diffuse panbronchiolitis ( DPB ) , we investigated T - cell subsets in bronchoalveolar lavage fluid ( BALF ) or 33 patients with DPB , nine patients with bronchiectasis , and 20 healthy volunteers . - pubmed
BALF from DPB patients contained a higher percentage of neutrophils than that from patients with bronchiectasis or healthy volunteers , whereas the percentage of lymphocytes was similar in the three groups . - pubmed
We describe an analysis of early B cell development in mice with X linked immunodeficiency ( Xid ) . - pubmed
Since 1986 , the authors have implanted 11 subcutaneous infusion ports in nine patients with hemophilia . - pubmed
There was a total of 6 infections ( 3 wound and 3 urinary tract ) in 6 patients among the 48 receiving cefazolin ( 12.5 % ) , whereas no infections were observed among the 54 patients who received cefonicid . - pubmed
METHODS : For 357 patients with primary open - angle glaucoma , the optic disk was morphometrically analyzed , and the intraocular pressure was measured in 24 - hour profiles . - pubmed
Epigastric island flaps were elevated 3 , 6 and 12 weeks after induction of DM in rats . - pubmed
In seven patients who had dyspnea the biopsies were done in erect or semi - erect sitting positions . - pubmed
Seroprevalences of Toxoplasma , malaria , rubella , cytomegalovirus , HIV and treponemal infections among pregnant women in Cotonou , Republic of Benin . - pubmed
Seroprevalences for toxoplasmosis , malaria , rubella , cytomegalovirus , HIV and treponemal infections were evaluated among 211 pregnant women residing in the Cotonou area , Republic of Benin . - pubmed
Routine serological screening should be recommended in young age and in pregnancy for rubella , only in pregnant women for HIV and toxoplasma infections , in order to control their possible consequences on women and newborns . - pubmed
We studied the effect of 12 - 36 min of global ischemia followed by 36 min of reperfusion in Langendorff perfused rabbit hearts ( n = 26 ) . - pubmed
Evidence of qualitatively altered nociception in patients with fibromyalgia . - pubmed
OBJECTIVE : To investigate the perception of pain in tender muscles of patients with fibromyalgia . - pubmed
METHODS : Twenty - five women with fibromyalgia and 25 healthy women were examined . - pubmed
Subjects then recorded their response to induced pain on a visual analog scale . - pubmed
CONCLUSION : This study demonstrates that nociception is qualitatively altered in patients with fibromyalgia , which is consistent with recent findings in other patients with tender muscles . - pubmed
[ Thrombocyto- and coagulopathies in patients with diabetic glomerulosclerosis and chronic glomerulonephritis ] . - pubmed
In this study we have devised a simple and robust PCR strategy to detect a wide range of viruses , bacteria , and parasites , all of which are capable of causing aseptic meningitis and encephalitis . - pubmed
OBJECTIVE : To evaluate the indications , techniques and outcome of organ - preserving tumour enucleation in patients with bilateral testicular germ cell tumours ( BTGCT ) rather than standard bilateral radical orchidectomy which results in loss of fertility and a lifelong requirement for androgen replacement . - pubmed
PATIENTS AND METHODS : In 13 patients with BTGCT of 6 - 30 mm in diameter , the tumours were enucleated under cold ischaemia after inguinal testicular exploration , and biopsies of the tumour bed and the peripheral parenchyma were taken . - pubmed
Six of the 13 patients underwent testicular radiation ( 20 Gy ) for carcinoma in situ ( CIS ) and five patients had adjuvant local therapy . - pubmed
RESULTS : The median follow - up was 62 months ( range 14 - 163 ) and the 13 patients are currently free of disease ; one patient had local recurrence 9 months after tumour enucleation but after orchidectomy the patient is free of disease after a follow - up of 156 months . - pubmed
CONCLUSIONS : These results suggest that organ - sparing surgery in patients with BTGCT represents a new therapeutic approach with endocrinological and psychological advantages . - pubmed
the tumour is organ - confined with no infiltration of the rete testis , multiple biopsies of the tumour bed and peripheral parenchyma should be taken , any associated CIS treated by radiation therapy , and patients must be followed closely . - pubmed
The relative activity of N -( beta - D - glucopyranosyl ) nicotinic acid to nicotinic acid in rats was 1/2.3 , 1/2.2 , 1/1.0 , and 1/1.7 as indices of the body weight gain , food intake , blood NAD content , and the increased urinary excretion of niacin and its metabolites , respectively . - pubmed
Archival biopsy specimens of oral dysplasia of squamous cell carcinoma from 64 patients were analysed immunohistochemically . - pubmed
Malignant cells of patients with cutaneous T cell lymphoma ( CTCL ) are of monoclonal origin and of the CD4+/CD45RO+ subset . - pubmed
A 53 - year - old man presented a melanotic lung tumor which was based in the bronchus of the left lower lobe and closed the left main bronchus . - pubmed
In recent years , several gene therapy procedures making use of retroviral vectors that selectively target HIV susceptible cells have been proposed in order to interfere with HIV productive infection . - pubmed
METHODS : Patients ( n = 84 ) with initial locally advanced rectal cancer ( uT3 / uT4 ) undergoing R0 resection were investigated after preoperative treatment that combined radiotherapy up to 45 Gy with two cycles of chemotherapy ( 5 - FU and leucovorin on d 1 - 5 and 22 - 28 ) . - pubmed
We reported a case of a thrombosis of the retinal and central artery and vein in a 44 - year - old patient , with high - grade T - cell lymphoma . - pubmed
BACKGROUND : The Irukandji syndrome is a group of delayed ( 10 - 40 mins , mean 30 mins ) severe systemic symptoms occurring after an initial mild skin sting by small carybdeid ( box ) jellyfish including Carukia barnesi , known colloquially as the ' Irukandji ' . - pubmed
In untreated rats , echocardiography revealed significant ( P<0.001 ) LV dilatation and systolic dysfunction compared with sham . - pubmed
Fluoroquinolones have been associated with peripheral sensory disorders and weakness , especially in patients with underlying myasthenia gravis or myasthenia - like Eaton - Lambert syndrome . - pubmed
We report a case of diffuse weakness due to a demyelinating polyneuropathy that began after initiation of trovafloxacin in a patient without an underlying neurologic disorder . - pubmed
Midazolam as a first - line agent for status epilepticus in children . - pubmed
However , midazolam as a first - line agent for status epilepticus in children has not been fully investigated . - pubmed
Intravenous midazolam was used for status epilepticus in 27 children ( 38 convulsive episodes ) from January 1997 to December 1999 in our hospital . - pubmed
Among them , 10 patients ( 16 convulsive episodes ) were treated with intravenous midazolam as a first - line agent . - pubmed
Midazolam seems to be effective and safe as a first - line therapy for status epilepticus in children . - pubmed
BACKGROUND : Successful pregnancies after conservative progestin treatment to young women with endometrial carcinoma have recently been reported . - pubmed
CASE : A 28 - year - old woman with endometrial carcinoma received conservative treatment with high - dose medroxyprogesterone acetate ( MPA ) and then conceived . - pubmed
METHODS : The Platelet IIb / IIIa in Unstable Angina : Receptor Suppression Using Integrilin Theraphy Trial ( PURSUIT ) enrolled 10,948 patients with non - ST - segment elevation acute coronary syndromes , including 585 in Latin America and 4358 in North America . - pubmed
METHODS : Twenty - one patients with PNP were categorized as mucosal dominant and mucocutaneous types based on clinical information . - pubmed
We analyzed the T - cell subsets in 28 patients with stable atopic asthma and 13 normal control subjects before and after 2 wk of treatment with prednisolone , 20 mg / d , or placebo in a randomized , double - blind , parallel group study . - pubmed
Products such as the tooth gel evaluated in this study may benefit dogs with xerostomia or other clinical conditions causing decreased saliva production . - pubmed
A 67 - year - old woman with anorexia and weight loss was referred to our hospital with a diagnosis of type 4 gastric cancer . - pubmed
Successful attempts at immunological cancer prevention in HER-2 / neu transgenic mice are described as an example . - pubmed
Although the very high rate of mammary carcinoma prevention in mice has generated enthusiasm , it should not be forgotten that such treatments , when administered to healthy humans at risk of cancer , may carry the risk of inducing autoimmunity . - pubmed
A 6 - wk - old child with FHL is presented . - pubmed
Atherosclerotic burden in coronary and peripheral arteries in patients with first clinical manifestation of coronary artery disease . - pubmed
The aim of our study was to assess the atherosclerotic burden in patients with the first symptoms of coronary artery disease ( CAD ) . - pubmed
The study population consisted of 100 consecutive patients ( new - onset severe angina or myocardial infarction ) and 70 age- and sex - matched volunteers without symptoms of CAD . - pubmed
Functional and morphologic atherosclerotic markers were sought in carotid , brachial , and femoral arteries of all subjects by means of high - resolution ultrasonography while coronary arteriography was performed in the CAD patients only . - pubmed
A total of 347 coronary lesions , 230 ( 66 % ) of them obstructive , were discovered in the CAD patients as well as 105 peripheral plaques , of which 26 ( 25 % ) were obstructive . - pubmed
Endothelium - dependent vasodilation , as assessed by the brachial flow - mediated response ( FMR ) , was reduced by 50 % in the CAD patients ( P< ; 0.001 vs controls ) ; it was also observed in carotid and femoral arteries by the cold pressor test . - pubmed
Furthermore , endothelium - independent vasodilation was significantly impaired in all investigated peripheral arteries of the CAD patients ( P< ; 0.05 - 0.001 vs controls ) . - pubmed
Intima - media thickness ( IMT ) was increased in the carotid arteries of the CAD patients by 43 % , in brachial arteries by 20 % , and in femoral arteries by 57 % ( P< ; 0.01 - 0.001 vs controls ) . - pubmed
Peripheral atherosclerosis was more developed in older patients but was similar in patients with different clinical presentation . - pubmed
In conclusion , the atherosclerotic process was quite advanced in coronary as well as peripheral arteries of our patients with the first clinical presentation of CAD . - pubmed
PURPOSE : In this prospective study we evaluate the effect of combined transurethral resection of early muscle invasive bladder cancer and immunotherapy with bacillus Calmette - Guerin ( BCG ) in patients unfit for radical cystectomy or refusing more aggressive therapies . - pubmed
Inclusion criteria were histologically proven muscle invasive transitional cell carcinoma of the bladder with a tumor - free second resection and negative staging examinations in patients unfit for radical cystectomy or refusing more aggressive therapies . - pubmed
One patient died of progressive recurrence in the upper urinary tract . - pubmed
CONCLUSIONS : The data show encouraging results for transurethral resection of bladder tumor with intravesical BCG therapy in select patients with T2a bladder cancer who are not candidates for radical cystectomy . - pubmed
The purpose of this chapter is to discuss the wealth of animal studies of stress - induced modulation of immunity , and to relate our understanding of stress and immunity to clinical populations , particularly cancer patients . - pubmed
More effective therapy is , therefore , needed for patients with metastatic RCC . - pubmed
CONCLUSION : These findings indicate that IAB-1 may have an antitumor activity against human RCC by inducing apoptosis , suggesting its potential clinical application for gene therapy against RCC . - pubmed
HYPOTHESIS : Aminophylline is a central respiratory stimulant and will decrease the incidence of PGE1 - associated apnea and the need for intubation for apnea in infants with ductal - dependent congenital heart disease . - pubmed
In a prospective , double - blinded , placebo - controlled study , newborn infants with ductal - dependent congenital heart disease were randomized to receive either aminophylline or placebo during initiation and maintenance of PGE1 , which was started at 0.01 microg / kg / min and increased to 0.03 microg / kg / min . - pubmed
Infants receiving aminophylline ( n = 21 ) were less likely to have apnea ( 2 vs 11 ) or be intubated for apnea ( 0 vs 6 ) . - pubmed
CONCLUSIONS : Aminophylline was effective for the prevention of apnea and intubation for apnea associated with PGE1 in infants with ductal - dependent congenital heart disease . - pubmed
Cutaneous candidiasis in a dog . - pubmed
This blinded , randomized , controlled trial of 112 patients studied time to graft thrombosis and graft loss , comparing monthly Qa plus standard surveillance ( dynamic venous pressure and physical examination ) ( treatment group ) to standard surveillance alone ( control group ) . - pubmed
The rate of graft thrombosis per patient - year at risk was 0.41 and 0.51 in the control and treatment groups , respectively . - pubmed
Second , using distinct bioinformatic tools , we set out to identify transcription factors that could be involved in the transcriptional regulation of genes known to be associated with aggressive behavior in mice . - pubmed
According to the data obtained in this work , the strains belong to a novel species , for which the name Paenibacillus favisporus sp . - pubmed
METHODS : The data was collected prospectively for all patients with STEMI who received thrombolysis in the emergency department over a one - year period from January 2001 to December 2001 . - pubmed
CONCLUSION : Emergency physicians can administer thrombolytic treatment appropriately , quickly and safely in patients with STEMI . - pubmed
OBJECTIVE : To describe and analyse the clinical characteristics of 100 patients with antiphospholipid syndrome ( APS ) associated with infections . - pubmed
The main associated infections and agents included skin infection ( 18 % ) , HIV ( 17 % ) , pneumonia ( 14 % ) , hepatitis C ( 13 % ) , and urinary tract infection ( 10 % ) . - pubmed
Twenty three patients died following infections and thrombotic episodes ( 16 with catastrophic APS ) . - pubmed
CONCLUSIONS : Various different infections can be associated with thrombotic events in patients with APS , including the potentially lethal subset termed catastrophic APS . - pubmed
Gram - negative bacteria of the Burkholderia cepacia complex ( Bcc ) are opportunistic pathogens that can infect the lungs of cystic fibrosis ( CF ) patients and can be transmitted among these patients , causing epidemics in the CF community . - pubmed
Although expansion of TNRs is associated with several human genetic diseases , the expansion mechanism is poorly understood . - pubmed
Carotenemia associated with green bean ingestion . - pubmed
Excessive and prolonged ingestion of carotene - rich , yellow- or orange - colored foods such as carrots and winter squash is the most common cause , but more rarely it may be associated with consumption of other foods as well as with hypothyroidism , diabetes mellitus , anorexia nervosa , liver disease , or kidney disease . - pubmed
Herein we describe carotenemia in an 8 - month - old Caucasian girl secondary to increased consumption of commercial infant food green beans . - pubmed
Severe acute respiratory syndrome ( SARS ) , a life - threatening disease , is caused by the newly identified virus SARS coronavirus ( SARS - CoV ) . - pubmed
DP - class prostaglandins and prostaglandin analogs ( collectively , prostaglandins or PGs ) such as PGD2 , BW245C , ZK110841 , and ZK118182 , lower intraocular pressure ( IOP ) in animal models of ocular hypertension . - pubmed
A new analog of ZK118182 ( AL-6556 ; 13,14 - dihydro - ZK118182 ) was synthesized , and the isopropyl ester of AL-6556 ( AL-6598 ) was shown recently to lower IOP in the ocular hypertensive cynomolgus monkey model of glaucoma and in human subjects . - pubmed
In 2002 , there were an estimated 13,400 emergency department visits nationwide for horse - related injuries among children younger than 15 years . - pubmed
Most serious injuries occur when a rider is thrown from a horse , which is often accompanied by being dragged or crushed by the horse . - pubmed
However , hoof kick injuries to an unmounted child represent about 30 % of horse - related injuries and may result in more severe injury . - pubmed
The effectiveness of helmets in preventing serious head injury in horse - related accidents has been very well established . - pubmed
Recommendations for the prevention of horse - related injury include requiring helmet use on and near a horse , use of safety stirrups to prevent drag injury , matching rider skill with the appropriate horse , and providing close adult supervision . - pubmed
A Turkish woman aged 44 years who presented with a 1 month history of abdominal pain , fatigue and weight loss of 10 kg was diagnosed as having acute tubulointerstitial nephritis . - pubmed
It is important to be aware of tubulointerstitial nephritis and uveitis syndrome in order to achieve a quick diagnosis in patients with renal impairment and tubular dysfunction with minor symptoms so that appropriate management can be started early . - pubmed
Three patients had MMG - positive BM , four patients had MMG - negative BM before allografting , and two were undetermined . - pubmed
Children hospitalized with skin and soft tissue infections : a guide to antibacterial selection and treatment . - pubmed
The main pathogens involved in these infections are Staphylococcus aureus and group A beta - hemolytic streptococci , but enteric organisms also play a role especially in nosocomial infections . - pubmed
A plasmid identified in a Bifidobacterium catenulatum strain ( pBC1 ) was chosen for further characterization based on its small size and stability . - pubmed
Hyperlipidemic mice present enhanced catabolism and higher mitochondrial ATP - sensitive K+ channel activity . - pubmed
We have recently shown that hypertriglyceridemic ( HTG ) mice present higher mitochondrial resting respiration unrelated to UCPs . - pubmed
In agreement with higher metabolic rates , food ingestion was significantly larger in HTG mice , without enhanced weight gain . - pubmed
CONCLUSIONS : These results show that primary hyperlipidemia leads to an elevation in liver mitoK(ATP ) activity , which may represent a regulated adaptation to oxidize excess fatty acids in HTG mice . - pubmed
Minocycline delays but does not attenuate the course of experimental autoimmune encephalomyelitis in Streptococcus pneumoniae - infected mice . - pubmed
OBJECTIVES : Experimental autoimmune encephalomyelitis ( EAE ) , the animal model of multiple sclerosis ( MS ) , can be aggravated by a mild Streptococcus pneumoniae infection . - pubmed
This study was performed to assess whether treatment with antibiotics inhibiting bacterial protein synthesis reduces the detrimental effect of infection on the course of EAE . - pubmed
Seven days after induction of EAE ( prior to the onset of symptoms ) mice were infected intraperitoneally with S. - pubmed
Mice treated with minocycline developed symptoms of EAE 1 day later than mice treated with ceftriaxone . - pubmed
These data do not support the hypothesis of superiority of a bacterial protein synthesis inhibitor over a beta - lactam antibiotic for the treatment of concomitant infections during the latent phase of EAE or MS . - pubmed
METHODS : An interventional study of 39 females with MVP syndrome with treadmill exercise endurance training for 12 weeks . - pubmed
Postural orthostatic tachycardia syndrome : anesthetic implications in the obstetric patient . - pubmed
Most of the tumors detected in Japanese quail were lymphosarcomas , and 81 % of these neoplasias contained CD3 + cells by immunoperoxidase . - pubmed
REV APC-566 was also oncogenic in chickens and turkeys infected at 1 day of age , with tumors appearing as early as 58 days after infection in chickens and at 13 wk of age in turkeys . - pubmed
Effects of isoflurane and sevoflurane anesthesia on arteriovenous shunt flow in the lower limb of diabetic patients without autonomic neuropathy . - pubmed
The aim of this study was to test the hypothesis that the function of arteriovenous anastomoses was disordered in mild diabetic patients without apparent neuropathy , and that volatile anesthetics opened arteriovenous shunts more greatly in nondiabetic patients than diabetic patients . - pubmed
Arterial - venous oxygen content difference ( A - VDeltaO2 ) and partial oxygen pressure index ( Pvo2 / Pao2 , the ratio of oxygen tension in femoral vein blood to that in femoral artery blood ) were measured before and during isoflurane or sevoflurane anesthesia in 16 diabetic and 22 nondiabetic patients . - pubmed
Skin temperatures of the foot and leg were measured in 14 diabetic and 15 nondiabetic patients using thermography before and during anesthesia . - pubmed
RESULTS : Pvo2 / Pao2 before anesthesia was significantly higher in diabetic patients . - pubmed
Foot temperatures were higher in diabetics before anesthesia , and increased gradually and significantly in both groups during anesthesia , but with a greater increase in nondiabetic patients . - pubmed
CONCLUSIONS : Diabetic patients have a higher Pvo2 / Pao2 and a small core - to - peripheral temperature gradient before anesthesia , suggesting latent dysfunction of the autonomic nerve system , even in the absence of autonomic neuropathy . - pubmed
Volatile anesthesia opens the arteriovenous shunt in nondiabetics to a greater extent than in diabetic patients . - pubmed
Echocardiography was performed on day 1 prior to AMI and on day 14 just before the rats were to be sacrificed for cellular and molecular studies . - pubmed
Additionally , day 14 left ventricular ( LV ) ejection fraction was significantly lower in nontreated AMI rats than in healthy control and losartan - treated AMI rats ( all values of P & lt ; 0.0001 ) . - pubmed
Topics covered in invited lectures included detection of novel respiratory viral pathogens and viral evolution , characterization of the 1918 pandemic virus , human metapneumovirus infections , human respiratory epithelial cultures for studying viral pathogenesis , the role of respiratory viruses in the pathogenesis of asthma , influenza - bacterial interactions , advances in generating vaccine candidates against global respiratory threats like avian influenza and SARS , antiviral resistance surveillance in influenza viruses , and a mini - symposium on advances in viral diagnostics . - pubmed
Other talks covered the live , attenuated intranasal influenza vaccine , monoclonals for respiratory syncytial virus ( RSV ) , mechanisms of antiviral resistance in influenza B , and novel inhibitors for influenza , RSV and rhinovirus infections . - pubmed
Toe - out gait in patients with knee osteoarthritis partially transforms external knee adduction moment into flexion moment during early stance phase of gait : a tri - planar kinetic mechanism . - pubmed
Altered gait kinematics and kinetics are observed in patients with medial compartment knee osteoarthritis . - pubmed
To test this hypothesis , gait data from 180 subjects diagnosed with medial compartment knee osteoarthritis were examined using two frames of reference . - pubmed
These results indicate that toe - out gait in patients with medial compartment knee osteoarthritis transforms a portion of the adduction moment into flexion moment in early stance phase , suggesting that load is partially shifted away from the medial compartment to other structures . - pubmed
PURPOSE OF REVIEW : The aim of this article is to review the recently published studies addressing various treatment approaches for asthma in preschool children . - pubmed
Once children at highest risk for persistence of wheezing are identified , various management strategies may be thoroughly studied . - pubmed
In addition to examining clinical efficacy , studies investigating the effects of these treatment modalities on the underlying airway inflammation have recently increased in number and quality and confirm the anti - inflammatory actions of these therapeutic strategies in the preschool child with asthma . - pubmed
SUMMARY : Evidence for the preferred treatment strategies for persistent asthma in young children remains incomplete . - pubmed
RESULTS : A total of 1,041 patients ( age : 11.8 + /- 4.2 years ; diabetes duration : 6.0 + /- 3.6 years ; average CSII duration : 2.0 + /- 1.3 years ; HbA(1c ): 8.0 + /- 1.3 % [ means + /- SD ] ) participated . - pubmed
( type strain MSL-09(T ) = KCTC 19272(T ) = DSM 19266(T ) ) , Nocardioides bigeumensis sp . - pubmed
( type strain MSL-19(T ) = KCTC 19290(T ) = DSM 19320(T ) ) and Nocardioides agariphilus sp . - pubmed
ARES is a multicenter , prospective study of the prevalence , management , and repercussions on the quality of life of anemia in renal transplant patients with a reduced renal function ( creatinine clearance according to Cockcroft - Gault : & lt;/=60 and & gt;15 mL / min ) . - pubmed
Treatment with oral or intravenous iron was much more frequent in anemic patients ( 31.6 % vs 9.9 % ; P & lt ; .001 ) . - pubmed
In conclusion , iron deficiency in renal transplant patients with chronic nephropathy is frequent and insufficiently treated . - pubmed
Although it may be an aggravating factor , it was not shown to be a determining factor for the presence or absence of anemia in the patients as a group . - pubmed
In this paper we expand these observations to demonstrate that these mice develop all the clinical and immunological features of primary Sjogren ' s disease in the same relative time frame as patients with primary Sjogren ' s disease : stage 1 - early hypergammaglobulinemia and autoantibody production , stage 2 - decreased salivary gland function with early lymphocytic infiltration of the submandibular glands only , but antibody deposition in the submandibular and parotid glands , stage 3 - lymphocytic infiltration of the submandibular , parotid and lacrimal glands with B and T lymphocytes and plasma cells along with interstitial lung disease and mild renal disease , and stage 4 - large B cell lymphoma . - pubmed
We explore whether patterns of covariation between fitness and ageing across 25 cytoplasmic lines , sampled from a population of Drosophila melanogaster , are consistent with the genetic associations predicted under MA or AP . - pubmed
[ The diurnal variability of blood pressure in patients with hypertension and rheumatoid arthritis ] . - pubmed
BACKGROUND : The patients with rheumatoid arthritis have high prevalence of hypertension and increased risk of cardiovascular morbidity and mortality . - pubmed
OBJECTIVE : To determine the level of clinical blood pressure ( BP ) and 24h ambulatory BP in patients with rheumatoid arthritis and hypertension . - pubmed
GROUP OF PATIENTS : 60 patients with clinically stable rheumatoid arthritis and treated or newly diagnosed hypertension . - pubmed
CONCLUSION : Patients with rheumatoid arthritis and hypertension have a slightly increased pulse pressure ( 55 mm Hg for clinical BP and 50 mm Hg for 24h ambulatory BP ) in comparison to arbitrary limits in generally population . - pubmed
Patients treated with prednison and nonsteroidal anti - inflammatory drugs were more often nondippers ( 34 % ) in systolic BP than hypertensive control . - pubmed
The patients treated with methotrexate ( 47 % ) , prednisone ( 37 % ) and nonsteroidal anti - inflammatory drugs ( 38 % ) were more often excessive dippers in diastolic BP than hypertensive control . - pubmed
Fusarium wilt ( FW ) is one of the most economically damaging cotton diseases worldwide , causing yellowing , wilting , defoliation , vascular tissue damage and ultimately death . - pubmed
The secondary objective of this study was to determine whether individuals at increased risk for developing voice problems ( i.e. - pubmed
Furthermore , the extended test was applied to 126 patients with olfactory loss and 71 normosmic individuals . - pubmed
infusion at doses between 1 and 16 mg / kg , with repeated dosing every 1 to 3 weeks ( based on patient - individualized PK assessment ) until disease progression . - pubmed
A phase II study is ongoing to evaluate the clinical activity of AS1402 in patients with advanced breast cancer . - pubmed
The effects of ciprofloxacin and ursodeoxycholic acid on bacterial translocation in obstructive jaundice . - pubmed
BACKGROUND / AIMS : We aimed to search the effects of two different drugs in bacterial translocation , both in combination and alone : ursodeoxycholic acid , the effectiveness of which was evidenced previously , and ciprofloxacin , which had not been used before , in an experimental obstructive jaundiced rat model . - pubmed
CONCLUSIONS : Ciprofloxacin and ursodeoxycholic acid have a synergic effect on prevention of bacterial translocation in obstructive jaundice . - pubmed
A study has been made of the pH stability of centrifugally purified strains of influenza virus with respect to the biological properties of mouse infectivity and chicken red blood cell agglutinating activity . - pubmed
in phosphate buffer , the infectivity of PR8 virus was found to be most stable at pH 6.5 - 7 ; the swine virus , at pH 7 - 7.9 ; and the Lee strain , at a pH of 7.9 or higher . - pubmed
Furthermore , the Lee virus was much less stable in dilute solution in phosphate buffer , even under optimum conditions of pH , than either the PR8 or swine strains . - pubmed
The different strains of influenza virus were found to possess certain characteristics in common . - pubmed
In detailed experiments with the Lee virus , it was found that the infectivity and CCA activity of this strain at pH 7 and at a protein concentration of 0.1 mg . - pubmed
Dopaminergic interneurons synapse onto cells that route signals to mammalian retinal ganglion cells , but it is unknown whether dopamine can activate receptors in these ganglion cells and , if it does , how this affects their excitability . - pubmed
Then , 11 patients who had been clinically diagnosed with Meniere ' s disease and a patient with sudden hearing loss were scanned . - pubmed
A newly - optimized protocol allowed the smooth , three - dimensional visualization of endolymphatic hydrops in all patients with Meniere ' s disease . - pubmed
CONCLUSION : Volumetrically separate visualization of endo-/perilymphatic space is now feasible in patients with Meniere ' s disease using an optimized 3D - real IR sequence , a 32 - channel head coil , at 3 T , after intratympanic administration of Gd - DTPA . - pubmed
Subtle genetic alterations in PSD proteins may induce neural network dysfunctions that may have some phenotypic relevance in human psychiatric disorders , as suggested in several recent studies . - pubmed
An anatomical study was carried out using six feline cadavers to determine anatomic landmarks . - pubmed
An ultrasonographic ' in vitro ' study was performed using eight pelvic limbs from four fresh feline cadavers to assess the ScN in three regions ( glutea , femoralis and popliteal ) using a 4 - 13MHz linear transducer . - pubmed
against paracetamol - induced hepatic injury in rats . - pubmed
OBJECTIVE : Methanol extract of whole plant of Amaranthus caudatus ( MEAC ) was screened for hepatoprotective potency against paracetamol ( PCM)-induced liver damage in Wistar rats . - pubmed
CONCLUSION : MEAC shows significant hepatoprotective activity against PCM - induced liver damage in rats . - pubmed
This finding supports the use of the plant in ethnomedicine for the treatment of liver diseases . - pubmed
OBJECTIVE : To determine the interrelationships between MRI - defined lesion and atrophy measures of spinal cord involvement and brain involvement and their relationships to disability in a small cohort of patients with multiple sclerosis ( MS ) . - pubmed
DESIGN AND METHODS : 3 T MRI of the whole brain and whole spinal cord was obtained in 21 patients with MS , including 18 with relapsing - remitting , one with secondary progressive , one with primary progressive , and one with a clinically isolated syndrome . - pubmed
CONCLUSIONS AND RELEVANCE : In this preliminary study of mildly disabled , treated MS patients , cervical spinal cord atrophy most strongly correlates with physical disability in MS when accounting for a wide range of other CNS measures of lesions and atrophy , including thoracic or whole spinal cord volume , and cerebral gray , white or whole brain volume . - pubmed
The weak relationship between spinal cord and brain lesions and atrophy may suggest that they progress rather independently in patients with MS . - pubmed
METHODS : Thirty - seven consecutive patients with adolescent idiopathic scoliosis were included in this study from June 2001 to August 2003 . - pubmed
heterophylla seeds ethanol extract ( VSE ) on mice model of immunological hepatitis and acute inflammation ] . - pubmed
heterophylla seeds ethanol extract(VSE ) on immunological hepatitis and acute inflammation mice model . - pubmed
Meanwhile , VSE could ameliorate the ear swelling induced by croton oil and reduced the thickness of mice hind paw induced by carrageenan as well . - pubmed
BACKGROUND : The incidence of children 's forearm fractures is increasing worldwide . - pubmed
MATERIALS AND METHODS : All 168 children ( & lt;16 years ) admitted to our paediatric trauma centre due to diaphyseal both - bone forearm fractures during 2000 - 2009 were included . - pubmed
Studies of allopurinol and febuxostat lowering of serum urate have once again raised the tantalizing possibility that hyperuricemia is harmful to the kidneys by showing better preservation of glomerular filtration rate ( GFR ) in treated patients . - pubmed
Running time to fatigue was significantly greater in HPdTSP mice than in TS mice . - pubmed
[ A retrospective study of UFT and oral leucovorin plus PSK combination adjuvant chemotherapy in patients with stage III colon cancer ] . - pubmed
SUBJECTS : Between 2003 and 2009 , 273 stage III colon cancer patients underwent surgery in our institute , and we studied 156 of them . - pubmed
Using 20 ng / mL as a cut - point value , 205 PCa patients , who underwent RP , were stratified into two groups . - pubmed
Patients , who might benefit the most from RP , are those with organ confined PCa and negative lymph nodes . - pubmed
RESULTS : Data from 158 relevant studies was used to characterise the epidemiology of the 10 most extensively reported maternal infections with the following median prevalence rates : Treponema pallidum ( 2.6 % ) , Neisseria gonorrhoeae ( 1.5 % ) , Chlamydia trachomatis ( 5.8 % ) , Group B Streptococcus ( 8.6 % ) , bacterial vaginosis ( 20.9 % ) , hepatitis B virus ( 4.3 % ) , hepatitis C virus ( 1.4 % ) , Cytomegalovirus ( 95.7 % past infection ) , Rubella ( 8.9 % susceptible ) and Herpes simplex ( 20.7 % ) . - pubmed
RESULTS : Out of the 209 patients , 43 ( 21 % ) were diagnosed with impingement syndrome or soft - tissue pathology . - pubmed
DBM administered in a sustained manner showed similar bone quality and strength to osteoporotic control animals . - pubmed
MATERIALS AND METHODS : Twenty - five patients ( M : F = 13:12 , mean age : 52.1 + -15.2 years ) with pathologically proven glioblastoma who underwent DSC MR imaging before surgery were included . - pubmed
Thus , we believe that DSC - enhanced perfusion MR imaging could be helpful in predicting genetic alterations that are crucial in predicting the prognosis of and selecting tailored treatment for glioblastoma patients . - pubmed
Orally active opioid mu / delta dual agonist MGM-16 , a derivative of the indole alkaloid mitragynine , exhibits potent antiallodynic effect on neuropathic pain in mice . - pubmed
Systemic administration of MGM-16 produced antinociceptive effects in a mouse acute pain model and antiallodynic effects in a chronic pain model . - pubmed
Postoperative pancreatic fistula developed in nine of 45 patients in the IRPJ group and 10 of 45 patients in the PG group ( P = 0.796 ) . - pubmed
Steatorrhea at 1 year was reported in nine of 42 IRPJ patients and 18 of 41 PG patients ( P = 0.029 ) . - pubmed
Evaluation of fracture risk and potential drug holidays for postmenopausal women on long - term bisphosphonate therapy . - pubmed
STUDY OBJECTIVE : To describe characteristics of postmenopausal women on long - term bisphosphonate therapy who fall into one of four fracture risk categories ( low , mild , moderate , high ) , and to determine the prevalence of women eligible for a drug holiday . - pubmed
PATIENTS : A total of 201 postmenopausal women of ages 55 - 89 years , with osteopenia or osteoporosis , prescribed bisphosphonate therapy for & gt;4 years , between October 10 , 2002 and September 9 , 2012 . - pubmed
Cytotoxicity of benzophenanthridine alkaloids from the roots of Zanthoxylum nitidum ( Roxb . ) - pubmed
Compounds 7 and 11 also showed strong cytotoxicity when tested against the four human cancer cell lines ( A549 , Hela , SMMC-7721 and EJ ) , while only compounds 12 and 13 displayed cytotoxicity in inhibiting BALL-1 proliferation among all the compounds . - pubmed
METHOD : Subjects were 928 Caucasian patients who presented to an out - patient clinic specializing in the assessment and treatment of anxiety and mood disorders . - pubmed
This interest , however , is tempered by a number of unresolved issues , including the safety of using such drugs in advanced CKD and ESRD populations , and the potential for differences in drug efficacy according to race and ethnicity of patient populations . - pubmed
Molecular characteristics of bap - positive Staphylococcus aureus strains from dairy cow mastitis . - pubmed
Major cardiovascular and cerebrovascular adverse events occurred in 1 patient , with no inhospital deaths observed . - pubmed
Vagus nerve stimulation ( VNS ) is generally considered as a palliative treatment for patients with drug - resistant partial - onset epilepsy . - pubmed
Screening of Probiotic Candidates in Human Oral Bacteria for the Prevention of Dental Disease . - pubmed
We screened 14 lactobacillus strains and 36 streptococcus strains out of 896 oral isolates derived from healthy subjects . - pubmed
As a result , Lactobacillus crispatus YIT 12319 , Lactobacillus fermentum YIT 12320 , Lactobacillus gasseri YIT 12321 , and Streptococcus mitis YIT 12322 were selected because they showed no cariogenic potential in an artificial mouth system and a lower risk of experimental infective endocarditis in a rat model . - pubmed
Clinical and pathological complete remission in a patient with metastatic renal cell carcinoma ( mRCC ) treated with sunitinib : Is mRCC curable with targeted therapy ? - pubmed
We report a patient with metastatic clear - cell renal cell carcinoma ( mRCC ) who presented with primary tumor in situ in the left kidney and metastases to bone , liver , lungs , and brain . - pubmed
STUDY DESIGN : Over a 1.5 - year period at a Chinese tertiary obstetric centre , women at risk of Hb Bart ' s disease were given the option of a non - invasive approach to exclude an affected pregnancy between 11 weeks and 13 weeks and 6 days of gestation , with a routine rescan after a 2 - week interval . - pubmed
Case 1 : A 35 - year - old woman who underwent right single LTx and sustained uncontrollable massive chylous ascites . - pubmed
Case 2 : A 50 - year - old woman who underwent left single LTx had pneumothorax of the native lung 16 months after the LTx . - pubmed
Case 3 : A 33 - year - old woman , who underwent left single LTx , had recurrence of LAM in the transplanted lung 2 years after the LTx . - pubmed
Case 4 : A 47 - year - old woman , who underwent right single LTx , developed repeated high fevers . - pubmed
[ Establishment of chondrocyte degeneration model in vitro by rat serum ] . - pubmed
CONCLUSION : The results indicate that rat serum can induce chondrocyte degeneration and may be used for osteoarthritis model in vitro . - pubmed
METHODS AND MATERIALS : Patients ( n = 21 ) treated with IGABT for carcinoma cervix under the IntErnational study on MRI - guided BRachytherapy in locally Advanced CErvical cancer protocol were analyzed . - pubmed
Bovine leukemia virus ( BLV ) is a deltaretrovirus which infects and induces proliferation of B - lymphocytes in the peripheral blood circulation and in lymphoid organs primarily of cattle , leading to leukemia / lymphoma . - pubmed
3 patients had severe bleeding ( 12.5 % , 3/24 ) in bridging group ; compared with the other 2 groups , there were significant difference ( chi(2)=9.161 , P=0.010 ) . - pubmed
Antipsychotics are the drugs used in the treatment of SCZ but it remains controversial the impact that typical vs. atypical antipsychotics has on the oxidative stress status in SCZ patients . - pubmed
Rice sheath blight disease , caused by the fungus Rhizoctonia solani , is considered the second most important disease of rice after blast . - pubmed
OBJECTIVE : To evaluate the diagnostic value of cytological greater omental milky spot examination for the diagnosis of peritoneal metastasis in gastric cancer patients . - pubmed
METHODS : A total of 136 patients diagnosed with gastric cancer and without distant metastasis were enrolled in our study . - pubmed
All patients underwent laparoscopy and CH40 suspension liquid dye of peritoneal lymph nodes preoperatively as well as ascites or peritoneal lavage fluid collections and excisions of marked greater omental milky spot tissues perioperatively . - pubmed
The GAlert SCs are deficient in self - renewal and subjected to accelerated depletion during regeneration and aging and fail to repair muscle injury in old mice . - pubmed
Increased FC was more common in patients with pancreatic insufficiency . - pubmed
Whether increased FC reflects intestinal inflammation in patients with CF remains to be determined . - pubmed
Fertility sparing approach as the standard of care in young patients with immature teratomas . - pubmed
[ Preoperative MRI diagnostics of the topographic features of neck arteries in the patients presenting with chronic tonsillitis ] . - pubmed
A total of 109 patients presenting with chronic tonsillitis ( including 64 women and 45 men at the age varying from 15 to 54 years ) were available for the examination . - pubmed
Abnormalities in the internal carotid artery were documented in 11.9 % of the cases ( including C- and S - shaped tortuosity of internal carotid artery in 6.88 % , kinking and coiling of internal carotid artery in 4.13 % and 0.92 % of the patients , respectively ) . - pubmed
The results of the present study should be taken into consideration when prescribing the surgical treatment to the patients suffering not only from chronic tonsillitis but also from other ENT diseases , in the first place pharyngotympanic tube pathology . - pubmed
RESULTS : A 41 - year - old man with a history of aniridic keratopathy and limbal stem cell deficiency underwent KLAL in his right eye . - pubmed
CONCLUSIONS : We present the first case of CMV disease in a seronegative patient who received a presumed CMV - seropositive donor KLAL . - pubmed
PURPOSE : To determine if preoperative Goldmann Visual Field ( GVF ) testing in patients with functional dermatochalasis accurately depicts the postoperative superior visual field ( SVF ) outcome . - pubmed
METHODS : A prospective cohort study was done to compare preoperative and postoperative GVF field tests in patients undergoing upper eyelid blepharoplasty for treatment of dermatochalasis . - pubmed
RESULTS : Forty - six eyelids ( 23 patients ) who underwent blepharoplasty for dermatochalasis were included . - pubmed
BACKGROUND : Transcatheter aortic valve implantation ( TAVI ) is an effective treatment for severe aortic stenosis in high - risk patients . - pubmed
OBJECTIVES : To assess the feasibility of recruitment and retention and to explore non - efficacy - based barriers to a blinded antipsychotic medication withdrawal programme for adults with LDs without psychosis compared with treatment as usual . - pubmed
PARTICIPANTS : Adults with LDs who are prescribed risperidone for treatment of challenging behaviour with no known current psychosis or previous recurrence of psychosis following prior drug reduction . - pubmed
The purpose of this review is to summarize recent advances that have allowed us to better recognize , categorize , and treat patients with DED . - pubmed
Patients with NASH show many features of the metabolic syndrome and , as a result , are at higher risk for postoperative cardiovascular morbidity and mortality . - pubmed
Despite this , patients with NASH have long - term graft and patient survival rates comparable with other causes of chronic liver disease . - pubmed
There are two large prospective randomized trials establishing the safety and efficacy of breast IORT in early stage breast cancer patients with sufficient follow - up time on thousands of women . - pubmed
The advantages of IORT for partial breast irradiation include : direct visualization of the target tissue ensuring treatment of the high - risk tissue and eliminating the risk of marginal miss ; the use of a single dose coordinated with the necessary surgical excision thereby reducing omission of radiation and the selection of mastectomy for women without access to a radiotherapy facility or unable to undergo several weeks of daily radiation ; favorable toxicity profiles ; patient convenience and cost savings ; radiobiological and tumor microenvironment conditions which lead to enhanced tumor control . - pubmed
It may also be very useful in specific situations , such as prior to oncoplastic reconstruction to improve accuracy of adjuvant radiation delivery , or when used as a boost in higher risk patients to improve tumor control . - pubmed
Non - pharmacological options for managing chronic musculoskeletal pain in children with pediatric rheumatic disease : a systematic review . - pubmed
Because CMP is not always alleviated solely by the use of pharmacological approaches , the aim was to systematically review the available evidence regarding non - pharmacological treatment options for reducing CMP in patients with PRD . - pubmed
Materials and Methods : In this study , infants and children who were referred for the evaluation of unilateral hydronephrosis were enrolled . - pubmed
Hemorrhagic bulla formation and the need for surgical intervention only presented for D. - pubmed
As to laboratory features , lower platelet counts ( 20.0 x 103 / muL [ interquartile range , 14 - 66 x 103 / muL ] vs. 149.0 x 103 / muL [ 102.3 - 274.3 x 103 / muL ] , P = 0.001 ) , lower D - dimer level ( 1423.4 mug / L [ 713.4 - 4212.3 mug / L ] vs. 12,500.0 mug / L [ 2351.4 - 200,000 mug / L ] , P = 0.008 ) , higher proportion of patients with moderate - to - severe thrombocytopenia ( platelet count & lt ; 100 x 103 / muL ) ( 80 % vs. 16.7 % , odds ratio ( OR ) = 20.0 , 95 % CI , 2.77 - 144.31 ; P = 0.002 ) , and lower proportion of patients with extremely high D - dimer ( & gt ; 5000 ng / mL ) ( 16.7 % vs. 66.7 % , adjusted OR = 0.1 ( 95 % CI , 0.01 - 0.69 ; P = 0.036 ) were found among cases of D. - pubmed
acutus envenomation compared to D. - pubmed
The combination of hemorrhagic bulla , thrombocytopenia , and a lack of extremely high D - dimer had good discriminatory power ( area under the curve ( AUC ) = 0.965 ; 95 % CI , 0.904 - 1.00 ) for distinguishing D. - pubmed
Conclusions : The presentation of moderate to severe thrombocytopenia ( platelet count & lt ; 100 x 103 / muL ) and hemorrhagic bulla formation may indicate D. - pubmed
These findings may help diagnose and select the right antivenom in patients with unknown snakebites who present significant coagulopathy . - pubmed
This study was to validate reliability and clinical utility of a PET tumor segmentation method using multi - level Otsu ( MO - PET ) in standard National Electrical Manufacturers Association ( NEMA ) image quality ( IQ ) phantom and patients with osteosarcoma . - pubmed
Repeated measurements of MTV ( MO - PET ) of the primary tumors showed excellent reproducibility with ICC of 0.994 ( 0.989 - 0.997 ) in patients with osteosarcoma . - pubmed
This emerging approach is changing how physicians diagnose and treat infectious disease , with applications spanning a wide range of areas , including antimicrobial resistance , the microbiome , human host gene expression ( transcriptomics ) and oncology . - pubmed
Isolation of Phage Lysins That Effectively Kill Pseudomonas aeruginosa in Mouse Models of Lung and Skin Infection . - pubmed
Evaluating the Impact of Different Hypercaloric Diets on Weight Gain , Insulin Resistance , Glucose Intolerance , and its Comorbidities in Rats . - pubmed
Animal experimentation has a long history in the study of metabolic syndrome - related disorders . - pubmed
Knowing that different diets can precipitate different metabolic disease phenotypes , herein we characterized several hypercaloric rat models of obesity and type 2 diabetes , comparing each with a genetic model , with the aim of identifying the most appropriate model of metabolic disease . - pubmed
All animal models presented with insulin resistance and dyslipidemia except the HF+STZ and HSu 4 weeks , which argues against the use of these models as metabolic syndrome models . - pubmed
We conclude that the latter model presents a phenotype most consistent with that observed in humans with metabolic disease , exhibiting the majority of the phenotypic features and comorbidities associated with type 2 diabetes in humans . - pubmed
Aim : This study aimed to compare smear layer removal ability of different solutions of Triphala ( TA ) when used in specific irrigant protocols in curved canals . - pubmed
Animal models of Sjogren ' s syndrome : an update . - pubmed
Animal models have served as useful tools for studying SS pathogenesis with several advantages . - pubmed
A number of animal models recapitulating key characteristics of primary SS patients including secretory dysfunction , glandular inflammation and presence of autoantibodies were developed in the past years . - pubmed
The studies based on the animal models of SS have provided significant insight in SS pathogenesis and therapeutic intervention . - pubmed
This review summarises current animal models with primary SS - like symptoms including spontaneous models , genetically modified models , induced models and humanised models , and discusses their contribution to the understanding of SS aetiology and therapies . - pubmed
Re : Comparison of outcomes between hip fracture patients with concurrent upper limb injuries and patients with an isolated hip fracture . - pubmed
OBJECTIVES : The goal of this secondary analysis was to examine whether N - acetylcysteine ( NAC ) reduced depressive symptoms among adults ( age 18 - 50 ) with CUD ( N = 302 ) and whether the effect of NAC on cannabis cessation varied as a result of baseline levels of depression . - pubmed
Adults with CUD ( N = 302 ) were randomized to receive 2400 mg of NAC daily or matched placebo for 12 weeks . - pubmed
OBJECTIVES : To examine the effects of corticosteroids on death in children and adults with sepsis . - pubmed
AUTHORS ' CONCLUSIONS : Moderate - certainty evidence indicates that corticosteroids probably reduce 28 - day and hospital mortality among patients with sepsis . - pubmed
Anisakis typica is one of the Anisakis species which potent to induce an allergic reaction . - pubmed
Role of Changes in Magnetic Resonance Imaging or Clinical Stage in Evaluation of Disease Progression for Men with Prostate Cancer on Active Surveillance . - pubmed
It is hypothesized that infarct stiffness alters regional mechanics and affects the likelihood of human ventricular remodeling . - pubmed
Identifying heat shock response systems from the genomic assembly of Ureibacillus thermophilus LM102 using protein - protein interaction networks . - pubmed
Aim : In the present research , we evaluated the synergistic effects of ketamine with two azole derivatives , itraconazole and fluconazole , on strains of Candida spp . - pubmed
METHODS : From 2016 to 2018 , 13 patients ( eight with scar contracture and five with a depressed scar ) were treated using dermofat grafts from the groin . - pubmed
The harvested dermofat was then inserted into the undermined dead space after the contracture was released , and a bolster suture was done for fixation considering the patient 's contour and asymmetry . - pubmed
Survival estimation of melanoma patients with brain metastasis using the Melanoma - molGPA score : external validation from a French cohort . - pubmed
Metastatic melanoma patients are a heterogeneous subgroup with variable prognosis . - pubmed
Melanoma molecular graded prognostic assessment ( Melanoma - molGPA ) is a new prognostic score for BM melanoma patients . - pubmed
As several prospective clinical trials are addressing the issue of optimal therapy including the impact of local treatment for these patients , the Melanoma - molGPA is a useful tool in BM melanoma patients . - pubmed
The larval form of tapeworms of the Echinococcus granulosus sensu lato species cluster cause an important zoonotic infection , cystic echinococcosis ( CE ) . - pubmed
In this work , we characterized isolates from human CE cases . - pubmed
Our findings suggest that pigs are important intermediate hosts for human CE in Slovenia . - pubmed
Purpose : Accumulating evidence has indicated that circRNAs are closely involved in tumorigenesis and progression of human cancers . - pubmed
First - line chemotherapy in very elderly patients with metastatic pancreatic cancer : Gemcitabine monotherapy vs combination chemotherapy . - pubmed
Considering the severe toxicities of combination chemotherapy , gemcitabine monotherapy ( G mono ) could be used as a first - line treatment in very elderly patients or those with a low Eastern Cooperative Oncology Group status . - pubmed
METHODS : We retrospectively analyzed 104 older patients with pancreatic cancer who underwent chemotherapy with G mono ( n = 45 ) or combination therapy ( n = 59 ) as a first - line treatment between 2011 and 2019 . - pubmed
All patients were histologically diagnosed with ductal adenocarcinoma . - pubmed
However , G mono is superior for the management of metastatic pancreatic cancer in very elderly patients . - pubmed
METHODS : We developed and validated a closely matched sham mindfulness intervention then compared it against 6 x 20 - minute sessions of focused - attention mindfulness and a no treatment condition in 93 healthy volunteers undergoing acute experimental heat pain . - pubmed
Infection with respiratory viruses such as influenza , respiratory syncytial virus and coronavirus provides a difficult immunological challenge for the host , where a balance must be established between controlling viral replication and limiting damage to the delicate lung structure . - pubmed
MATERIALS AND METHODS : Public datasets of COVID-19 ( N = 130 ) , bacterial pneumonia ( N = 145 ) , non - COVID-19 viral pneumonia ( N = 145 ) , and normal ( N = 138 ) CXRs were analyzed . - pubmed
Although substantial progress has been made over the past 40 years in treating patients with cancer , effective therapies for those who are diagnosed with advanced metastatic disease are still few and far between . - pubmed
Between 2003 and 2018 , four patients recorded with anterior nasal floor perforation with dental implants were followed and reviewed with panoramic radiographs and cone - beam computed tomography . - pubmed
RESULTS : The most prevalent genotype was HPV 16 , with an increasing presence depending on the severity of the CIN and with the highest incidence in the 26 - 35 age range . - pubmed
A different distribution of HPV presence was observed depending on CIN grade ( P<0.001 ): CIN1 HPV negative samples were 46.3 % , CIN2 : 5.8 % and CIN3 : 1.4 % . - pubmed
Moreover , within CIN1 , 85 % of them were associated to negative HPV detection , this observation suggested that the detection of HPV presence may be useful to identify low CIN grade that should be reconsidered for surgical treatment . - pubmed
CONCLUSIONS : These findings suggest implementing the protocol for the management of women with high risk precancer lesions , with a further HPV test before surgical treatment . - pubmed
Tg MSCs administered after the onset of Escherichia coli - induced sepsis maintained their ability to improve survival when given in a single dose , in contrast with WT MSCs . - pubmed
AIMS : Current guidelines recommend surgery within 48 hours among patients presenting with hip fractures ; however , optimal surgical timing for patients on oral anticoagulants ( OACs ) remains unclear . - pubmed
METHODS : We searched MEDLINE , EMBASE , and the Cochrane Central Register of Controlled Trials ( CENTRAL ) from inception to 14 October 2019 to identify studies directly comparing outcomes among hip fracture patients receiving direct oral anticoagulants ( DOACs ) or vitamin K antagonists ( VKAs ) prior to hospital admission to hip fracture patients not on OACs . - pubmed
TTS was 13.7 hours longer ( 95 % confidence interval ( CI ) 9.8 to 17.5 ; p < 0.001 ) among hip fracture patients on OACs compared to those not on OACs . - pubmed
Evaluating expedited surgical protocols in hip fracture patients on OACs is an urgent priority , with the potential to decrease morbidity and mortality in this group of high - risk patients . - pubmed
Temporal lobe epilepsy ( TLE ) is one of the most common and intractable neurological disorders in adults . - pubmed
The induction of squamous cell carcinomas and papillomas in a total of 1,950 mice in a lifelong skin - dropping experiment with different doses of automobile exhaust condensate and its fractions is described . - pubmed
Ciliary arrest in Phragmatopoma gills was produced by an amount of energy , sufficient to cause a rise in temperature of 150 degrees C in an area of 2 micron3 . - pubmed
Colonization of the respiratory tract with Pseudomonas aeruginosa is a serious problem in cystic fibrosis and seriously ill hospitalized patients . - pubmed
Polyamine metabolism in colonic mucosa from patients with ulcerative colitis . - pubmed
Polyamine metabolism in mucosa both from patients in the active or remission stage of ulcerative colitis ( UC ) and from healthy controls was studied . - pubmed
In 22 patients with 1 - year follow - up , IORT prevented local recurrence in 14 ( 64 % ) patients . - pubmed
Recovery from fatigue of human diaphragm and limb muscles . - pubmed
This study was designed to compare the recovery from fatigue of human inspiratory and limb muscles using repeated maximal static contractions . - pubmed
Our major conclusions are that the human diaphragm has a marked capacity to recover from fatigue and that this may have been underestimated in previous studies from this and other laboratories . - pubmed
To verify whether methylmalonic acid accumulates in adult heterozygotes for inherited methylmalonic - acidaemia and thereby gives " false " positive test results for cobalamin deficiency , we measured the concentration of methylmalonic acid in serum and its urinary excretion in six patients of three children with severe methylmalonic - acidaemia . - pubmed
It also contains a discussion of the origins pruritus in elderly people . - pubmed
The authors discuss the results of surgical treatment of 105 patients with benign neoplasms of the mediastinum . - pubmed
The results of complex treatment of 81 patients with pyoinflammatory diseases with the use of blood ultraviolet irradiation are discussed . - pubmed
Whole body plasma extravasation in saline and Haemaccel loaded rats : effects of endotoxemia . - pubmed
Are lymphangiograms necessary before placing patients with nonseminomatous testicular tumors on surveillance ? - pubmed
Lymphangiographic findings in 174 patients with early stage nonseminomatous testicular tumors were evaluated retrospectively to determine the need to perform the procedure before patients are placed on surveillance . - pubmed
When physical examination , chest x - ray , computerized tomographic scans and serum tumor marker levels were normal , lymphangiography detected unsuspected metastasis in only 4 per cent of the patients , while providing misinformation in another 4 per cent . - pubmed
Plain radiographs of 99 patients on surveillance taken at 2 - month intervals resulted in only 1 instance when the x - rays became positive and were the first evidence of metastasis . - pubmed
[ Contingent negative variation in normal and dyslexic children ] . - pubmed
Nine right handed boys aged between 9 and 13 years with reading disabilities were studied . - pubmed
A study on the anti - cancer effect of ningxia wolfberry . - pubmed
This study has expanded the number of patients , who were divided into two groups : six patients with pure ADHD , and 13 patients with ADHD in combination with other neurologic symptoms . - pubmed
In a patient receiving phenytoin who presents a viral - like illness , early recognition and discontinuation of the drug are mandatory . - pubmed
From 1976 to 1983 , 28 patients ( 24 male and four female ) with unresectable hepatocellular carcinoma ( HCC ) were treated by intraarterial chemotherapy at the Istituto Nazionale Tumori of Milan , Milan , Italy . - pubmed
Systemic toxicity was mild , but the treatment induced hepatic toxicity ( ascites , clinical jaundice , or biochemical impairment ) in 18 % of noncirrhotic and 66 % of cirrhotic patients . - pubmed
Clinical reduction of hepatomegaly was observed in 50 % of noncirrhotic versus 16 % of cirrhotic patients . - pubmed
5 - fluorouracil was effective only in patients without cirrhosis , with an overall response rate of 22 % . - pubmed
This study emphasized the negative impact of the treatment on cirrhotic patients . - pubmed
A patient is described in whom , 2 months after an acute myocardial infarction , inducible coronary artery spasm and a nonocclusive thrombus were angiographically demonstrated at the site of a minimal atherosclerotic narrowing in the infarction - related vessel . - pubmed
Amnionitis caused by Propionibacterium acnes . - pubmed
A patient with bilateral pulmonary arteriovenous fistulae is described who was treated successfully by embolization of the two fistulae with detachable balloons introduced percutaneously through the femoral vein . - pubmed
The biochemical response to an intravenous alanine load of 0.25 g / kg was studied in nine adult female relatives of children with ornithine carbamoyltransferase deficiency . - pubmed
Eight patients from Zaire with Mycobacterium ulcerans infection were treated by the local application of heat to maintain a temperature of approximately 40 degrees C in the ulcerated area . - pubmed
[ Pseudomonas aeruginosa infection serotyping . - pubmed
[ Pressure in the duodenum and effect on it of certain preparations in patients with chronic pancreatitis ] . - pubmed
Group R streptococcus infections in man . - pubmed
The interaction of diet and microflora in experimental caries in the rat . - pubmed
Nifedipine for the poor - risk elderly patient with achalasia : objective response demonstrated by solid meal study . - pubmed
We described an 84 - year - old woman with symptomatic achalasia who refused both dilation and surgical treatment . - pubmed
Hypertension and proteinuria : long - term sequelae of uninephrectomy in humans . - pubmed
Cytotoxic cell activity directed against paternal alloantigens was investigated in primiparous C57BL/10 and CBA / Ca mice using a microcytotoxicity assay . - pubmed
Protective role of dietary butylated hydroxyanisole against chemical - induced acute liver damage in mice . - pubmed
Prior consumption of a diet containing the food antioxidant , butylated hydroxyanisole ( BHA ) , by female mice prevented the development of or minimized the acute liver damage caused by monocrotaline , acetaminophen , or bromobenzene . - pubmed
The protective effect of BHA against acetaminophen - induced hepatotoxicity was not demonstrated in male mice . - pubmed
[ Effect of mechanical asphyxia on lipid peroxidation processes in the rat brain ] . - pubmed
Repetitive treatment with the organotropic colon carcinogen , 1,2 - dimethylhydrazine ( DMH ) , produces tumors in susceptible mouse strains that exhibit pathological features associated with the human disease . - pubmed
As in human populations , the genetic background of laboratory animals comprises a significant component to this organ - specific carcinogenesis , and several mouse lines , including AKR / J and DBA/2J are highly resistant to the tumorigenic effects of DMH . - pubmed
The suspected cause of these ulcers -- disturbed cutaneous microcirculation -- was studied by simultaneously measuring laser - Doppler flux ( LDF ) and cutaneous oxygen tension ( pCUO2 ) in 14 patients with DNPU at three differently affected sites ( dorsal forefoot , ulcer edge , lower leg ) . - pubmed
We could detect GFP protein in transgenic strains and found that its accumulation , conveniently visualized in living flies using epifluorescence microscopy , was limited to the indirect flight muscles . - pubmed
Independent of testosterone , ritanserin reduced locomotion and exploration and increased anxiety in males , while DOI increased locomotion and exploration in both sexes . - pubmed
This report presents five cases of BFP ( Guillain - Barre syndrome , herpes simplex polyneuritis , meningeal lymphoma , and two cases of bilateral Bell ' s palsy ) in which MRI imaging helped in the diagnosis and subsequent management of the patient . - pubmed
The appropriate sequence of diagnostic studies for patients with BFP is discussed . - pubmed
In a population of 716 patients with end - stage renal disease ( ESRD ) , 46 patients ( 6.4 % ) were identified as having pancreatitis . - pubmed
The presence of risk factors including age , hypertension , hypercholesterolemia , tobacco use , diabetes mellitus and hyperuricemia were also examined . - pubmed
In a previous study , we observed that suppression of T - cell proliferation induced by Salmonella infection is associated with inhibition of tyrosine phosphorylation in T - cells , and that a cell - free Salmonella typhimurium LT2 extract ( LT2 extract ) also suppressed mitogen - induced T - cell proliferation . - pubmed
Reduced humoral immunity in uremic mice genetically selected for high antibody response . - pubmed
Osteoporosis is a common disease among patients undergoing transplantation . - pubmed
We present a study of 27 women who underwent BMT , all of them suffering ovarian failure . - pubmed
Osteopenia was observed in nine patients ( 33 % ) and osteoporosis in another five ( 18 % ) , according to the World Health Organization criteria . - pubmed
We outline a reasonable therapeutic approach for osteoporosis in BMT emphasizing the need to monitor these patients after transplantation . - pubmed
Cystic fibrosis and non - cystic - fibrosis human nasal epithelium show analogous Na+ absorption and reversible block by phenamil . - pubmed
Transepithelial short - circuit current ( ISC ) , potential ( VT ) and resistance ( RT ) of confluent monolayers of human nasal epithelium cultured from patients with and without cystic fibrosis ( CF ) were measured . - pubmed
We present two patients with primary carcinoid tumor of the pancreas , which metastasized to the liver . - pubmed
Carcinoid tumor should be considered in the differential diagnosis of a pancreatic mass in a patient with carcinoid syndrome , but lack of this syndrome does not exclude the diagnosis . - pubmed
Although viraemia was detected in the third horse by virus isolation , from 6 to 14 days after infection , this animal remained consistently negative by RT - PCR . - pubmed
Conversely , AHSV viral RNA was detected by RT - PCR in the blood of 4 donkeys and 4 mules up to 55 days after their experimental infection despite the absence of any detectable infectious virus . - pubmed
RT - PCR is a sensitive and rapid method for detecting AHSV nucleic acids during either the incubation period at the start of an African horse sickness ( AHS ) epizootic , or for epidemiological investigations in species where clinical signs may be inapparent . - pubmed
A retrospective analysis with a minimum 49 - month follow - up identified 18 patients ( mean age , 61.3 years ) with culture - positive infections and exposed prosthetic grafts in the infrainguinal region . - pubmed
It is generally recognized that the initial step in the formation of atherosclerotic plaque in humans involves the peroxidation of low density lipoproteins ( LDL ) . - pubmed
Patient outcome after endovascular treatment of intracranial aneurysms with reference to microsurgical clipping . - pubmed
Indications for screening and follow - up of the patients as limitations and recent achievements of aneurysm embolization are discussed . - pubmed
Clinical status of all 15 patients with unruptured aneurysms preserved . - pubmed
STUDY DESIGN : Case - control study including 29 patients with endometriosis and 15 controls . - pubmed
We report on the clinical manifestations in six affected individuals from a four - generation family that segregates brachydactyly type D ( BDD ) . - pubmed
All affected individuals have either bilateral and symmetric or unilateral first distal phalangeal hypoplasia . - pubmed
Are heroin overdose deaths related to patient release after prehospital treatment with naloxone ? - pubmed
Results from several studies performed in relevant animal models have demonstrated that Mycobacterium tuberculosis secreted antigens may represent major components of improved TB vaccines . - pubmed
Like tardive dyskinesia , blepharospasm can be disfiguring and aesthetically distressing , contributing to the increased stigmatization of patients . - pubmed
CASE REPORTS : We report 4 patients with DSM - IV schizoaffective disorder , paranoid schizophrenia , or chronic undifferentiated schizophrenia who developed neuroleptic - induced blepharospasm . - pubmed
In all patients , blepharospasm remitted without the reemergence of psychosis within 3 to 5 months of treatment with clozapine , 100 - 200 mg / day . - pubmed
CONCLUSION : The results suggest that clozapine may successfully treat neuroleptic - induced blepharospasm without the reemergence of psychosis in patients with schizophrenia , schizoaffective disorder , or schizophreniform disorder . - pubmed
Preclinical validation of this approach is reviewed with the goal of using this immunotherapy for metastatic human cancers . - pubmed
CONCLUSIONS : BARI physicians were able to select PTCA rather than CABG for 65 % of registry patients who underwent revascularization without compromising long - term survival either in the overall population or in treated diabetics . - pubmed
By identifying the proteins these genes encode and the mechanisms by which the genes influence an animal 's biochemical response to alcohol , scientists can gain insight into the features of human alcoholism and provide a basis for developing pharmaceuticals that short - circuit these genetically defined processes . - pubmed
[ Culture of Plasmodium berghei with the short life span in mouse erythrocytes : evaluation of chloroquine resistance in three strains of the malaria parasite ] . - pubmed
These included 1 ) chloroquine - sensitive H strain ; 2 ) LNK-65 strain having a spontaneously 2 - 3 - fold decreased sensitivity to the agent ; 3 ) strain LNK-65 ChR selected for high resistance to chloroquine . - pubmed
OBJECTIVE : To examine the role of ultrasound versus magnetic resonance imaging ( MRI ) in assessing joint inflammation in patients with juvenile idiopathic arthritis ( JIA ) of the knee . - pubmed
METHODS : This study was conducted on 38 patients with juvenile idiopathic arthritis ( 25 girls and 13 boys ) , whose ages ranged between 2 - 17 years ( mean 8 years ) , presenting with joint swelling , tenderness , pain on motion and/or limitation of movement . - pubmed
Skin only or silo closure in the critically ill patient with an open abdomen . - pubmed
METHODS : A retrospective review was made of all trauma or general surgery patients who underwent an open abdominal closure from January 1997 to December 2000 , at a large urban acute care hospital . - pubmed
RESULTS : From 1997 to 2000 , 181 patients ( aged 39.8 + /- 16.5 years ) had an open abdomen for abdominal infection , planned reexploration , abdominal compartment syndrome , inability to reapproximate fascia , or as part of a " damage control " procedure . - pubmed
Gastrointestinal fistulas occurred in 26 patients , and 9 patients had a dehiscence . - pubmed
Therefore , we enrolled 14 MDS patients ( 4 RA , 2 RARS , 6 RAEB , 2 CMML ) , 44 - 80 ( median 60 ) years old , in a pilot trial . - pubmed
Thus , etanercept treatment resulted in moderate improvements of cytopenias in some patients , while cell counts declined in others . - pubmed
Communication challenges in a young man with Hodgkin ' s disease . - pubmed
DNA methylation in the androgen receptor gene promoter region in rat prostate cancers . - pubmed
All of the examined rat prostate and seminal vesicle cancers demonstrated hypermethylation at these CpG sites . - pubmed
NTP Toxicology and Carcinogenesis studies were conducted by administering furfural ( 99 % pure ) in corn oil by gavage to groups of F344 / N rats and B6C3F1 mice of each sex for 16 days , 13 weeks , or 2 years . - pubmed
Genetic toxicology studies were conducted in Salmonella typhimurium , mouse lymphoma cells , Chinese hamster ovary ( CHO ) cells , Drosophila melanogaster , and mouse bone marrow cells . - pubmed
Final mean body weights of chemically exposed animals were similar to those of vehicle controls ; no compound - related histologic lesions were observed in any dosed groups . - pubmed
Most rats that received 180 mg / kg died ; mean body weights of chemically exposed rats were similar to those of vehicle controls . - pubmed
Mean body weights of chemically exposed mice were similar to those of vehicle controls throughout the studies . - pubmed
Mean absolute liver weights and liver weight to body weight ratios were increased in females that received 300 mg / kg . - pubmed
Centrilobular coagulative necrosis and/or multifocal subchronic inflammation of the liver were present in chemically exposed mice but not in vehicle control mice . - pubmed
Body Weight and Survival in the Two - Year Studies : Mean body weights of chemically exposed and vehicle control animals were similar throughout the studies for rats and mice . - pubmed
Survival of high dose female rats was reduced by deaths associated with gavage administration ; the administration of furfural was considered to be a contributing factor in these gavage - related deaths . - pubmed
Nonneoplastic and Neoplastic Effects in the Two - Year Studies : Centrilobular necrosis of the liver occurred at increased incidences in chemically exposed male rats ( vehicle control , 3/50 ; low dose , 9/50 ; high dose , 12/50 ) . - pubmed
Two high dose male rats had bile duct dysplasia with fibrosis , and two had cholangiocarcinomas ; neither lesion was seen in the other dose groups . - pubmed
The historical incidence of bile duct neoplasms in corn oil vehicle control male rats is 3/2,145 ( 0.1 % ) . - pubmed
Multifocal pigmentation and chronic inflammation of the subserosa of the liver occurred in chemically exposed mice ( pigmentation -- male : 0/50 ; 0/50 ; 8/49 ; 18/50 ; female : 0/50 ; 0/50 ; 0/50 ; 11/50 ; chronic inflammation -- male : 0/50 ; 0/50 ; 8/49 ; 18/50 ; female : 0/50 ; 0/50 ; 1/50 ; 8/50 ) . - pubmed
The incidences of hepatocellular adenomas and hepatocellular carcinomas in male mice and hepatocellular adenomas in female mice were significantly increased in the high dose group compared with those in the vehicle controls ( male -- adenomas : 9/50 ; 13/50 ; 11/49 ; 19/50 ; carcinomas : 7/50 ; 12/50 ; 6/49 ; 21/50 ; female -- adenomas : 1/50 ; 3/50 ; 5/50 ; 8/50 ; adenomas or carcinomas , combined : 5/50 ; 3/50 ; 7/50 ; 12/50 ) . - pubmed
Three renal cortical adenomas or carcinomas occurred in chemically exposed male mice ( 0/50 ; 1/50 ; 1/49 ; 1/50 ) , and a renal cortical adenoma was present in one low dose female mouse ; the historical incidence oal incidence of renal cortical neoplasms in National Toxicology Program 2 - year corn oil gavage studies in male B6C3F1 mice is 8/2,183 . - pubmed
Forestomach hyperplasia occurred in chemically exposed female mice , and squamous cell papillomas were increased in high dose female mice ( hyperplasia : 0/50 ; 5/50 ; 5/50 ; 3/50 ; papillomas : 1/50 ; 0/50 ; 1/50 ; 6/50 ) . - pubmed
melanogaster ; furfural did not induce SCEs or chromosomal aberrations in the bone marrow of B6C3F1 mice . - pubmed
Conclusions : Under the conditions of these 2 - year gavage studies , there was some evidence of carcinogenic activity of furfural for male F344 / N rats based on the occurrence of uncommon cholangiocarcinomas in two animals and bile duct dysplasia with fibrosis in two other animals . - pubmed
There was clear evidence of carcinogenic activity for male B6C3F1 mice , based on increased incidences of hepatocellular adenomas and hepatocellular carcinomas . - pubmed
There was some evidence of carcinogenic activity in female B6C3F1 mice , based on increased incidences of hepatocellular adenomas . - pubmed
Renal cortical adenomas or carcinomas in male mice and squamous cell papillomas of the forestomach in female mice may have been related to exposure to furfural . - pubmed
BACKGROUND / AIMS : To compare two non - invasive techniques of assessing wound healing , photography and high resolution ultrasound ( HRUS ) scanning , in experimentally induced full - thickness human skin wounds . - pubmed
METHODS : Punch biopsy wounds , 4 mm in diameter , were made aseptically through locally anaesthetised skin on the anterior ( volar ) surface of the non - dominant forearm , 3 cm below the base of the cubital fossa , of 20 human participants . - pubmed
However most forms of human obesity do not appear to entail elevated plasma glucocorticoids . - pubmed
Twenty - five patients with a prominent zygoma underwent reduction malarplasty from January 1995 through January 2001 . - pubmed
Immunophenotypic and viral ( human papillomavirus ) correlates of vulvar seborrheic keratosis . - pubmed
In recent years , HPV has been detected in vulvar epithelial changes lacking koilocytosis , including squamous papillomas and lesions closely resembling seborrheic keratosis ( SK ) . - pubmed
Eighteen of 25 VSKs ( 72 % ) , 0 of 10 nondiagnostic vulvar acanthuses ( 0 % ; P = 0.0001 ) , 2 of 12 FEPs ( 16.7 % ; P = 0.004 ) , and 3 of 20 CSKs ( 15 % ; P = 0.0002 ) scored HPV positive . - pubmed
MATERIALS AND METHODS : We reviewed frozen section examination of the resection surfaces of 131 consecutive patients surgically treated for squamous cell carcinoma of the lower lip during the period January 1980 to January 1999 . - pubmed
In 8 patients ( 6 % ) , a local recurrence developed . - pubmed
In this multicenter study , performed in emergency departments , 130 patients with acute respiratory failure were randomized to receive medical therapy plus O2 ( 65 patients ) or noninvasive pressure support ventilation ( 65 patients ) . - pubmed
Noninvasive pressure support ventilation does , however , reduce the intubation rate in the subgroup of hypercapnic patients . - pubmed
[ First cases of dermatophytosis caused by Microsporum audouini in Bosanska Krajina ] . - pubmed
A kinetic study of local lesion growth on Nicotiana glutinosa resulting from tobacco mosaic virus infection . - pubmed
Chromatographic separations on DEAE cellulose have been carried out on the seromucoid fraction from forty - one normal individuals and twenty - three patients horpitalized with unilateral pneumococcal pneumonia . - pubmed
The seromucoid pattern of seven patients with acute leukemia differed from that of the control groups and also differed from that observed in patients with pneumonia . - pubmed
We report a patient with a sufficiently thick cornea ( 593 microm ) and no topographic signs of keratoconus preoperatively who developed iatrogenic keratoconus 2 months after repeat laser in situ keratomileusis ( -4.00 -1.00 x 20 ) performed 5 months after the primary procedure ( -10.50 -1.00 x 55 ) . - pubmed
This technique has been performed in 67 patients harboring sellar and parasellar lesions . - pubmed
Precipitation reaction of the sera obtained from the patients of various types of pulmonary infection against anti - lung - tissue immune serum and anti - pulmonary - cavity content immune serum . - pubmed
EHS tumor arose spontaneously in an ST / Eh strain mouse and has been propagated by transplantation . - pubmed
Clinical predictors in obstructive sleep apnoea patients with calibrated cephalometric analysis -- a new approach . - pubmed
Concomitant infection with streptococci and C. - pubmed
Bleeding , temporary renal failure , acute respiratory distress syndrome , and graft infection occurred in one patient each ; all recovered from these complications . - pubmed
Although preclinical data suggest that new drugs can modulate or slow prostate tumor proliferation , responses in man , such as disease stabilization or regression , are not as dramatic as those seen in preclinical models . - pubmed
Comparison of left ventricular and biventricular pacing in patients with heart failure . - pubmed
Our case indicates that myomatous uterus in premenopausal women shows the potential pitfall of a positive result of FDG - PET . - pubmed
OBJECTIVE : To investigate the effectiveness and complication rate of intravaginal gemeprost , a prostaglandin E ( 1 ) analogue , for second - trimester pregnancy termination in women with a scarred uterus . - pubmed
RESULTS : The rate of successful abortions among women with uterine scars was not different from that observed in the nulliparous controls , but previously vaginal delivery was associated with a shorter induction to abortion interval . - pubmed
OBJECTIVE : To evaluate associations linking glucocorticoid dose changes in patients with polymyalgia rheumatica ( PMR ) to the PMR activity score ( PMR - AS ) and its components . - pubmed
A rat osteoporotic spine model for the evaluation of bioresorbable bone cements . - pubmed
To further test this hypothesis , a suitable animal model is needed to evaluate the in vivo behavior of potential biomaterials in osteoporotic bone . - pubmed
CONCLUSIONS : Future investigation of potential biomaterials intended for the local treatment of osteoporosis will require their study within an appropriate osteoporosis animal model . - pubmed
The effectiveness of ureteric reimplantation during bladder augmentation for high - grade vesicoureteric reflux in patients with neurogenic bladder : long - term outcome . - pubmed
PURPOSE : The outcome of ureteric reimplantation ( UR ) during bladder augmentation ( BA ) for high - grade vesicoureteric reflux ( HVUR ) in patients with neurogenic bladder was assessed to determine the effectiveness of UR . - pubmed
METHODS : Twenty - two consecutive sigmoidocolocystoplasty patients were reviewed retrospectively ; 10 had unilateral HVUR only , 3 had bilateral HVUR , and 9 had unilateral HVUR associated with low - grade VUR in the contralateral renal unit ( RU ) . - pubmed
Urinary tract infection , universal preoperatively , was seen postoperatively in only 2 patients . - pubmed
CONCLUSIONS : Ureteric reimplantation during BA is safe and effective for treating HVUR in patients with neurogenic bladder . - pubmed
This meta - analysis aimed to assess the middle - term outcomes after crural angioplasty in patients with chronic critical limb ischemia and compare results with a meta - analysis of popliteal - to - distal vein bypass graft . - pubmed
Two - year follow - up of splenic radiofrequency ablation in patients with cirrhotic hypersplenism : does increased hepatic arterial flow induce liver regeneration ? - pubmed
Since the introduction of radiofrequency ablation ( RFA ) for patients with cirrhotic hypersplenism , we observed a phenomenon of visible hepatic regeneration . - pubmed
METHODS : Forty patients who underwent splenic RFA for cirrhotic hypersplenism were followed for 24 months . - pubmed
Patients with & gt ; or = 40 % of spleen volume ablated had better improvement of thrombocytopenia . - pubmed
A 16 - year - old man had a traumatic accident during motor - cross racing and sustained an anterior hip dislocation with fracture of anterior superior and anterior inferior iliac spines . - pubmed
The valgus instability of 24 patients ( 12 isolated injuries and 12 multiple ligament injuries ) who suffered MCL injury between 1993 and 1998 was evaluated with the Hughston and Eilers classification , which involves radiographic assessment under manual valgus stress to the injured knees . - pubmed
The results of the study show that iodine supplementation to weaner , non - iodine deficient euthyroid rats at 3ppm not only retard weight gain but could also reduce fertility by lowering epididymal sperm counts . - pubmed
Reversal of cadmium - induced thyroid dysfunction by selenium , zinc , or their combination in rat . - pubmed
The aim of this study was to evaluate the potential benefit of combined treatment with zinc ( Zn ) and selenium ( Se ) in reversing cadmium ( Cd)-induced thyroid dysfunction compared to Se or Zn treatment alone in rats exposed to Cd . - pubmed
The treatment of Cd - exposed animals with Zn alone partially protected against Cd - induced thyroid dysfunction by maintaining normal RTW and by decreasing Cd concentration in the thyroid . - pubmed
STUDY DESIGN : Between January 1 , 1977 , and December 31 , 2006 , 142 patients with high - risk metastatic GTN were treated . - pubmed
Hysterectomy was performed in 42 of 142 high - risk patients ; metastases were resected in 26 of 142 of high - risk patients . - pubmed
CONCLUSION : Results support that patients with high - risk metastatic GTN should primarily be treated with combination chemotherapy . - pubmed
This study was to investigate its antitumor effects on tumor cell xenografts in mice . - pubmed
METHODS : The inhibitory effects of raddeanin A on the proliferation of human nasopharyngeal carcinoma KB cells and ovarian cancer SKOV3 cells were measured by MTT assay . - pubmed
The inhibitory effects of raddeanin A injection on the growth of sarcoma S180 , liver cancer H22 and cervical carcinoma U14 cell xenografts in mice and the effect of raddeanin A lavage on the growth of S180 cell xenografts were measured . - pubmed
METHODS : From 16 patients , we obtained paired fine needle aspiration biopsies ( FNABs ) of breast cancers taken before ( PRE ) and after ( POST ) their surgeries and compared the microarray data to determine the genes that were differentially expressed between the FNABs taken at the two time points . - pubmed
All patients underwent DSAEK for Fuchs endothelial dystrophy , pseudophakic bullous keratopathy , aphakic bullous keratopathy , failed graft , or iridocorneo endothelial syndrome . - pubmed
Tobacco smoking has wide spread systemic effects , many of which may provide mechanisms for the increased susceptibility to periodontitis and the poorer response to treatment . - pubmed
CONCLUSION : Tobacco smoking is a significant risk factor for periodontal disease . - pubmed
Multiple and simultaneous intraatrial bipolar recordings from 27 patients in AF were analyzed before and after infusing a propofol bolus . - pubmed
The status of rainbow trout genetic maps has progressed significantly over the last decade due to interest in this species in aquaculture and sport fisheries , and as a model research organism for studies related to carcinogenesis , toxicology , comparative immunology , disease ecology , physiology and nutrition . - pubmed
BACKGROUND AND OBJECTIVES : Observational studies have reported earlier onset of psychosis in schizophrenic patients with a history of cannabis use . - pubmed
We aimed to examine whether cannabis use determined an earlier onset of schizophrenia in a sample of first episode patients , in an area with one of Europe 's highest rates of cannabis use . - pubmed
Transgenic mouse models of human diseases have gained increasing importance in the pathophysiology of cardiovascular diseases ( CVD ) . - pubmed
The existing imaging literature on the neurobiological correlates of fear processing and anxiety disorders points to a pivotal role of the amygdala in the human fear circuit . - pubmed
Longitudinal studies in patient samples will be required to elucidate how genetically influenced neurobiological intermediate phenotypes are associated with subtype , severity and the course of anxiety disorders , thereby having the potential for developing individualized therapy regimes derived from neurobiological research . - pubmed
METHODS : A 70 % hepatic reperfusion model of rats was established , setting groups of sham - operation and injury ones with different reperfusion time . - pubmed
The findings of our case suggest that for a neurofibromatosis 1 patient , a good prognosis can be expected even if a huge destructive intrathoracic intrusion is detected . - pubmed
We will discuss the definition , diagnosis , and treatment of patients with atypical meningioma ; review the current phase II cooperative trials ; and draw attention to some questions timely for pre - clinical and clinical research . - pubmed
Early assessment of treatment response in patients with AML using [ ( 18 ) F ] FLT PET imaging . - pubmed
We investigated the use of positron emission tomography ( PET ) for early assessment of treatment response in patients with acute myeloid leukemia ( AML ) , using the proliferation marker 3 '- deoxy-3 '-[( 18 ) F ] fluoro - l - thymidine ( FLT ) . - pubmed
In the trial group ( patients having remnant ACL , n = 38 ) , there were 27 males and 11 females with an average age of 24.3 years ( range , 16 - 43 years ) ; of them , 8 cases complicated by meniscus injury and 13 cases by Outbridge I degree cartilage injury ; the time from injury to operation was 3 - 20 weeks ( mean , 8.6 weeks ) . - pubmed
In the control group ( patients having no remnant ACL , n = 59 ) , there were 35 males and 24 females with an average age of 27.8 years ( range , 18 - 48 years ) ; of them , 16 cases complicated by meniscus injury and 23 cases by Outbridge I degree cartilage injury ; the time from injury to operation was 4 - 44 weeks ( mean , 12.7 weeks ) . - pubmed
Knee instability disappeared ; the patients showed negative anterior drawer test and negative Lackman test . - pubmed
METHODS : A multicenter , inter - group , cross - sectional study was conducted in 905 adult symptomatic patients with JC pollinosis to investigate the Japanese Allergic Rhinitis Standard QOL Questionnaire ( JRQLQ ) . - pubmed
Giant atrial myxoma mimicking severe mitral stenosis in young patient . - pubmed
The echocardiogram of a twenty - year - old man , previously healthy , suffering from paroxysmal nocturnal dyspnea and fatigue after moderate exertion that intensified over a period of about ten days , showed the left atrium myxoma working as severe mitral stenosis . - pubmed
Despite rapid advances in cancer diagnosis and treatment , pancreatic cancer remains one of the most difficult human malignancies to be treated , with a mortality rate nearly equal to its incidence . - pubmed
These secondary lesions are responsible for significant impairment of quality of life of patients with onset of pain , which is frequently resistant to standard analgesics . - pubmed
The therapeutic challenge for a patient with spinal metastasis is to maintain a quality of life as good as possible , commensurate with its life expectancy . - pubmed
Stereotactic radiosurgery could be provided for patients with single lesions or oligometastatic disease , a good general condition , absence of cord compression , and a life expectancy greater than 6 months . - pubmed
Decreased axonal density and altered expression profiles of axonal guidance genes underlying lead ( Pb ) neurodevelopmental toxicity at early embryonic stages in the zebrafish . - pubmed
Previous studies have reported that environmental lead ( Pb ) exposure can result in neurological alterations in children leading to reduced IQ , attention deficit hyperactivity disorder , and diminished reading and learning abilities . - pubmed
The intensities of infection by P. - pubmed
There is limited to moderate evidence to support improvements in dynamic postural stability , and patient perceived functional stability through neuromuscular training in subjects with CAI . - pubmed
Infection by hepatitis B virus ( HBV ) and dietary exposure to aflatoxin B ( 1 ) ( AFB ( 1 ) ) are the main risk factors for the development of chronic liver disease and hepatocellular carcinoma ( HCC ) . - pubmed
OBJECTIVE : Refractory schizophrenia ( SZ ) affects approximately 30 % of people with SZ . - pubmed
Why do human phobias last for months or years when such behavior should undergo extinction ? - pubmed
This failure of extinction or persistence of self - defeating behavior of human disorders was labeled by Mowrer as the neurotic paradox . - pubmed
, implosive therapy ) are combined with ( b ) principles examined in laboratory research that are combined to generate unique predictions that correspond to known features of human phobic behavior . - pubmed
This combination of factors effectively precludes extinction to main conditioned aversive stimuli for nonhumans , as it does for human phobias . - pubmed
Support for a laboratory model of human phobia is thereby attained . - pubmed
To search for a better strategy for the prevention and treatment of KD , this study compared and validated human KD immunopathogenesis in a mouse model of Lactobacillus casei cell wall extract ( LCWE)-induced coronary arteritis . - pubmed
Blood samples from KD patients were collected before and after IVIG treatment , and cardiovascular abnormalities were examined by transthoracic echocardiography . - pubmed
Wild - type male BALB / c mice ( 4 - week - old ) were intraperitoneally injected with LCWE ( 1 mg / mL ) to induce coronary arteritis . - pubmed
Glucose metabolism and diabetogenic gene expression analysis of chloroform fraction of Andrographis paniculata ( Nees ) whole herb in diabetic albino mice . - pubmed
The aim of the present work was to analyze the anti - diabetic potential of chloroform fraction of ethanol extract of Andrographis paniculata ( AP ) and diabetes laden gene expression alteration . - pubmed
In diabetic mice , the fraction reduced the level of harmful cholesterol , while increased the favorable cholesterol significantly . - pubmed
MATERIALS AND METHODS : Serum samples from 30 adult patients ( 22 males and 8 females , median age 37 , range 19 - 66 years ) with AML had been taken before chemotherapy was administered . - pubmed
Ten samples from healthy normal persons of matched age and sex were evaluated as a reference control group . - pubmed
The treatment of dermatophytoses due to Microsporum canis is cumbersome and relapses can occur . - pubmed
Volatile essential oils ( EOs ) obtained from plants would seem to represent suitable tools to contrast mycoses both in human and animals . - pubmed
difficile strains were subjected to the broth dilution method to determine minimum inhibitory concentrations ( MIC ) and minimum bactericidal concentrations ( MBC ) for Manuka honey . - pubmed
difficile strains , in which increasing concentrations of Manuka honey resulted in increasing size of zone of inhibition formed . - pubmed
difficile is appreciably susceptible to Manuka honey and this may offer an effective way of treating infections caused by the organism . - pubmed
This serovar appears to affect men who have sex with men ( MSM ) , most of them being co - infected with the Human Immunodeficiency Virus ( HIV ) . - pubmed
The present study addressed the role of HA matrix for progression and prognosis of human bladder cancer by studying the expression and function of HA - related genes . - pubmed
METHODS : Tissue samples of 120 patients with different stages of transitional cell bladder cancer , who underwent surgical treatment for bladder cancer at the University Hospital of Essen were analysed . - pubmed
CONCLUSIONS : PK evaluation may help identify adolescents at risk of excessive DMPA - associated weight gain . - pubmed
OBJECTIVE : To analyze the relationship between birth weight and elevated blood pressure among schoolchildren aged 6 - 11 years in 8 provinces of China . - pubmed
CONCLUSION : Current BMI but not birth weight was found to be a strong determinant of elevated blood pressure among children aged 6 - 11 years in China . - pubmed
This is a case report of odontogenic myxoma in a 32 year old female patient and the treatment rendered to her . - pubmed
Atorvastatin decreases inflammation and thrombogenesis in patients with carotid artery plaque . - pubmed
Eighty - nine patients from northeastern China with acute ischemic stroke caused by large - artery atherosclerosis were randomly divided into the study and control groups . - pubmed
These results suggest that atorvastatin reduces inflammation and thrombogenesis independent of its lipid - lowering effects in patients with acute ischemic stroke caused by large - artery atherosclerosis . - pubmed
Bacteriophage J-1 was isolated in 1965 from an abnormal fermentation of Yakult using Lactobacillus casei strain Shirota , and a related phage , PL-1 , was subsequently recovered from a strain resistant to J-1 . - pubmed
This preliminary study sought to analyze the effects of a training program based on the Proprioceptive Neuromuscular Facilitation ( PNF ) method on motor recovery of individuals with chronic post - stroke hemiparesis . - pubmed
Here we report the case of a 37 - year - old patient with ENS and severe functional impairment , who was diagnosed with a somatic symptom disorder and treated accordingly . - pubmed
At month 6 , the patient was displaying back - to - normal levels of functioning and was no longer seeking care for ENS . - pubmed
RESULTS : Of 249 patients enrolled , 171 showed thrombus on baseline computed tomography . - pubmed
In 34 patients ( 19.9 % , nonvolume reduction ; either no change or thrombus volume increased ) , overall thrombus volume increased . - pubmed
In the placement of these devices particular attention and effort must be made to understand safe and reliable anatomic techniques and device maintenance so as to avoid serious injury to the patient . - pubmed
Human adipose tissue expansion in pregnancy is impaired in gestational diabetes mellitus . - pubmed
This study aimed to investigate human AT expandability during pregnancy and its role in the pathogenesis of gestational diabetes mellitus ( GDM ) . - pubmed
METHODS : All patients with severe and severe / complicated CDI refractory to oral vancomycin + - rectal vancomycin and intravenous metronidazole therapy were offered FMT . - pubmed
Of the two patients who died within 30 days , one underwent colectomy and succumbed to sepsis ; the other died from septic shock related to CDI . - pubmed
Patient was diagnosed with midventricular SCM . - pubmed
Comparison of quercetin and resveratrol in the prevention of injury due to testicular torsion / detorsion in rats . - pubmed
We compared their effects in testicular torsion / detorsion ( T / D ) in adult rats . - pubmed
This study investigates the potential disruptions in prefrontal - hippocampus structural and functional connectivity , as well as their relationship in first - episode medication - naive adolescents with MDD in order to investigate the early stage of the illness without confounds of illness course and medication exposure . - pubmed
METHODS : Diffusion tensor imaging and resting - state functional magnetic resonance imaging ( rs - fMRI ) data were acquired from 26 first - episode medication - naive MDD adolescents and 31 healthy controls ( HC ) . - pubmed
PATIENTS AND METHODS : A trained professional conducted a periodontal examination in 40 patients with RA aged 23 to 73 years ( 85 % women ) . - pubmed
RESULTS : Thirty five of the 40 patients had periodontitis and in 13 , it was severe . - pubmed
Patients using higher doses of corticosteroids had lower severity of periodontitis . - pubmed
CONCLUSIONS : Periodontitis is common and severe in patients with RA , and is influenced by gender , age , smoking and corticosteroid dose . - pubmed
METHODS : Serial pharmacokinetic / pharmacodynamic measurements and Sieving coefficients were assessed in two patients with severe influenza B infection requiring organ replacement therapy . - pubmed
RESULTS : Patient # 1 , a 9 - year - old female with severe influenza B virus infection , biventricular assist device , and continuous veno - venous hemodiafiltration , received 75 mg oral oseltamivir twice - daily for 2 days , then intravenous oseltamivir with one - time renoprotective dosing ( 40 mg ) , followed by regular intravenous administration of 100 mg twice - daily . - pubmed
Patient # 2 , a 28 - year - old female with influenza B virus infection requiring extracorporeal membrane oxygenation , received 75 mg oral oseltamivir twice - daily , resulting in erratic oseltamivir blood concentrations . - pubmed
Evidence - based pediatric dosing recommendations and effective intravenous antiviral treatment modalities are needed for intensive care patients with life - threatening influenza disease . - pubmed
Role of Berberine in the Treatment of Methicillin - Resistant Staphylococcus aureus Infections . - pubmed
These findings will provide new insights into the multiple pharmacological properties of berberine in the treatment of microbial - generated amyloid involved diseases . - pubmed
Recent studies have identified impairments in neural induction and in striatal and cortical neurogenesis in Huntington ' s disease ( HD ) knock - in mouse models and associated embryonic stem cell lines . - pubmed
The triple - negative breast cancer ( TNBC ) is a very aggressive tumor type often occurring in young women and is associated with a bad prognosis for the patients . - pubmed
BACKGROUND : Pruritus is the hallmark clinical sign of atopic dermatitis ( AD ) in dogs . - pubmed
ANIMALS : Clinicians at 15 referral clinics enrolled 211 client owned dogs with a history of chronic AD . - pubmed
Dog owners assessed visual analog scale ( VAS ) scores of pruritus on days 0 , 1 , 2 , 3 , 7 , 14 , 21 , 28 , 35 , 42 , 49 and 56 . - pubmed
Clinicians assessed Canine AD Extent and Severity Index ( CADESI-03 ) scores on days 0 , 7 , 14 , 28 , 42 and 56 . - pubmed
Further studies are needed to better understand variability in individual responses across a broader population of dogs with AD . - pubmed
cremoris IBB477 strain , previously shown to persist in the gastrointestinal tract of germ - free rats . - pubmed
Rhizobium radiobacter in pulmonary abscess associated with postgripal necrotizing pneumonia . - pubmed
Although in the last years poliovirus ( PV ) transmission has been reported at the lowest levels ever recorded , the spread of virus from endemic countries endures ; the high levels of immigration flows across the Mediterranean Sea jeopardize Italy for PV reintroduction . - pubmed
In addition , the Environmental Surveillance ( ES ) , seeking the presence of PV and Non - Polio Enterovirus ( NPEV ) in sewage , is recognized as a powerful tool to confirm PV circulation in absence of AFP cases , especially in polio - free countries . - pubmed
The aim of this study was to review the outcomes of a series of breast cancer patients who underwent sentinel node biopsy inclusive of lymphoscintigraphy , and to assess the incidence of internal mammary node ( IMN ) metastatic positivity at exploration and whether these findings influenced treatment . - pubmed
METHODS AND RESULTS : Pigs implanted with single - chamber implantable cardioverter defibrillators to record ventricular arrhythmias ( VAs ) were subjected to percutaneous coronary occlusion to induce myocardial infarction . - pubmed
OBJECTIVE : To determine the long - term safety and outcomes of mesenchymal stem cells ( MSCs ) for bronchopulmonary dysplasia in premature infants enrolled in a previous phase I clinical trial up to 2 years of corrected age ( CA ) . - pubmed
In the present study , patients with unprovoked late - onset seizures and without known neoplasm , who might have had paraneoplastic encephalitis , were investigated for a potentially underlying autoimmunity . - pubmed
METHODS : Sixty - six consecutive patients ( 36 women ; aged & gt;=55 years ) after having at least one seizure or seizures for & lt;=6 months were prospectively identified over a period of 4.75 years . - pubmed
SIGNIFICANCE : Our findings suggest that autoimmunity should be considered an important etiology in patients with late - onset seizures . - pubmed
Task - Specific and Functional Effects of Speed - Focused Elliptical or Motor - Assisted Cycle Training in Children With Bilateral Cerebral Palsy : Randomized Clinical Trial . - pubmed
METHODS : A total of 27 children with bilateral CP , 5 to 17 years old , were randomized to 12 weeks of 20 minutes , 5 days per week home - based training ( elliptical = 14 ; cycle = 13 ) at a minimum of 40 revolutions per minute , with resistance added when speed target was achieved . - pubmed
RESULTS : The adrenal medulla of the HFD rats showed prominent structural changes , such as hypertrophy of chromaffin and ganglion cells , vacuolation , inflammatory foci , and fibrosis . - pubmed
A fundamental issue is to understand the residual capacity of those LBD patients in tool selection . - pubmed
METHODS : Three LBD patients with tool use disorders , three right brain - damaged ( RBD ) patients , and six matched healthy controls performed a novel tool selection task , consisting in extracting a target out from a box by selecting the relevant tool among eight , four , or two tools . - pubmed
By using positron emission tomography , our study demonstrated neuroinflammation in the brain of patients with ME / CFS . - pubmed
Neuroinflammation was found to be widespread in the brain areas of the patients with ME / CFS and was associated with the severity of their neuropsychological symptoms . - pubmed
We investigated in a rodent model of intrauterine growth restriction ( IUGR ) induced by maternal protein restriction ( R ) during gestation which time window of maternal undernutrition ( gestation , lactation or gestation - lactation ) has more impact on the male offspring metabolomics phenotype . - pubmed
In contrast , IUGR rats displayed permanently impaired beta - oxidation , associated to increased glucose or BCAA oxidation at adulthood , depending on the fact that pups experienced slow postnatal or catch - up growth , as suckled by R or C dams , respectively . - pubmed
Analysis of 246 sentinel lymph node biopsies of patients with clinical primary breast cancer by application of carbon nanoparticle suspension . - pubmed
Successful retrograde recanalization of acute right dominant vertebral artery occlusion through the left posterior communicating artery in a patient with acute vertebrobasilar ischemic stroke . - pubmed
Infertile women have a high incidence of latent GTB and treatment improves fertility outcomes . - pubmed
Group I consisted of infertile women with proven tubal patency but with latent GTB diagnosed by DNA PCR testing of an endometrial biopsy . - pubmed
Postoperative complications and 90 - day mortality in radical cystectomy in high - risk patients : A monocentric retrospective observational study . - pubmed
AIM : Assessing the incidence of immediate postoperative complications and 90 - day mortality in high - risk patients who have undergone radical cystectomy ; evaluating the correlation between preoperative conditions and surgery outcomes . - pubmed
In 28 % of patients , no complications arose , while in 46 % grades I - II complications according to Clavien - Dindo occurred , in 23 % grades III - IV complications occurred , and in 3 % of the patients , death arose in the immediate postoperative period ( grade V ) . - pubmed
The HA stalk - specific antibody response is associated with protection from homologous , heterologous , and heterosubtypic influenza virus infection in mice . - pubmed
Restoring vasculogenic potential of endothelial cells from diabetic patients through spheroid formation . - pubmed
Among other issues , patients with diabetes suffer from diminished endothelial cell ( EC ) function , which contributes to impaired vasculogenesis and recovery from ischemic insult . - pubmed
Methods : We hypothesized that forming human microvascular endothelial cells ( HMVECs ) from diabetic patients into spheroids would restore their vasculogenic potential following upregulation of these cell - cell interactions . - pubmed
Results : Individual HMVECs from diabetic patients exhibited similar proliferative and chemotactic potential to cells from healthy donors but reduced tubulogenesis . - pubmed
This study demonstrates a promising approach for restoring the diminished vasculogenic potential of endothelial cells in diabetic patients . - pubmed
The current study aimed to investigate the modulatory effects of amitriptyline on bleomycin - induced pulmonary fibrosis in rats . - pubmed
In the nude mice , THZ2 also suppressed the growth of xenograft tumors of gastric cancer . - pubmed
A virus was readily transmitted mechanically from young leaves of each of the two ilarvirus - negative trees to Chenopodium quinoa and Nicotiana occidentalis strain ' 37B ' , which within 5 days , developed systemic mottle and necrotic flecking , respectively . - pubmed
METHODS : In this retrospective chart review , we evaluated our cohort of patients treated with a treatment paradigm for CNV in AMD . - pubmed
A 74 - year - old diabetic man with prior right total knee arthroplasty and MRSA infection presented with persistent bacteremia and sepsis . - pubmed
RATIONALE AND OBJECTIVES : Requests for gastrostomy tube placement in patients on aspirin ( ASA ) 325 mg are common , particularly in patients following reconstructive surgery for head and neck cancer , but periprocedural guidelines and recommendations regarding management of high dose aspirin are inconsistent . - pubmed
The purpose of this study was to assess the bleeding risk of percutaneous gastrostomy tube placement in patients on ASA 325 mg . - pubmed
MATERIALS AND METHODS : This retrospective study of 213 patients who underwent image - guided " push " percutaneous gastrostomy tube placement compared rates of significant bleeding and other secondary outcomes ( including all - cause mortality within 30 days , procedure - related mortality , bowel perforation , abdominal abscess , peritonitis , aspiration pneumonia , intraprocedural airway complications , and tube dislodgement ) between patients maintained on ASA 325 mg and patients not on antiplatelet or anticoagulation therapy . - pubmed
RESULTS : No significant bleeding episodes occurred in patients on ASA 325 mg , compared to three episodes in patients not on ASA 325 mg ( p = 0.37 ) . - pubmed
A patient in each group had aspiration pneumonia possibly related to tube placement . - pubmed
Response to the Rechallenge With Talimogene Laherparepvec ( T - VEC ) After Ipilimumab / Nivolumab Treatment in Patient With Cutaneous Malignant Melanoma Who Initially Had a Progression on T - VEC With Pembrolizumab . - pubmed
An 83 - year - old man developed a subungual lesion of the left thumb and found to have AJCC V. 7 stage IIIb melanoma . - pubmed
Responsiveness to Change of the Montreal Cognitive Assessment , Mini - Mental State Examination , and SCOPA - Cog in Non - Demented Patients with Parkinson ' s Disease . - pubmed
BACKGROUND : Clinical monitoring of patients with Parkinson ' s disease ( PD ) for cognitive decline is an important element of care . - pubmed
METHODS : PD patients without dementia were enrolled at 6 North American movement disorders centers between 2008 and 2011 . - pubmed
CONCLUSION : Using neuropsychological testing as a gold standard comparator , the performance of the MoCA , MMSE , and SCOPA - Cog for detecting decline in non - demented PD patients over a 1 - year interval is poor . - pubmed
METHODS : A prospective study that includes patients aged & gt;= 69 years that live at home before the fracture , admitted from June 1st , 2010 , to May 31st , 2013 . - pubmed
Correction : paediatric goal management training in patients with acquired brain injury : study protocol for a randomised controlled trial . - pubmed
Phacoemulsification , visco - goniosynechialysis , and goniotomy in patients with primary angle - closure glaucoma : A comparative study . - pubmed
OBJECTIVE : The aim of this study was to evaluate the effects of goniotomy on patients with primary angle - closure glaucoma who underwent " phacoemulsification and visco - goniosynechialysis . " - pubmed
MATERIALS AND METHODS : This prospective randomized clinical trial was carried out on 63 eyes of 61 patients ( 48 - 85 years ) with primary angle - closure glaucoma who were enrolled . - pubmed
None of the patients developed a full refeeding syndrome . - pubmed
As an alternative , the cat is an unfamiliar but powerful model of human asthma . - pubmed
Furthermore , induced pluripotent stem cell ( iPSC)-derived neurons of patient with Down syndrome showed absence of LTP or LTD . - pubmed
We observed that the growth of xenograft tumors derived from NSCLC cell lines in nude mice was significantly inhibited by combination therapy . - pubmed
For the stroke mouse model , FCCP ( 1 mg / kg , i.p ) or vehicle was administered followed by 1 - hour transient middle cerebral artery occlusion ( tMCAO ) . - pubmed
The mice pretreated with FCCP had a significantly increased infarct volume within the cortex , striatum , and total hemisphere . - pubmed
Mice receiving FCCP had a significantly increased neurological deficit score compared to the vehicle . - pubmed
Uncoupling the electron transport chain with FCCP prior to tMCAO exacerbated stroke infarction in mice . - pubmed
RESULTS : We included 682 cysts for 621 patients , the imaging performed was relevant in 55 % of cases , not relevant but justified in 25 % and irrelevant in 20 % . - pubmed
Here , we evaluated the prognostic value of HRQoL using the Functional Assessment of Cancer Therapy - General ( FACT - G ) in advanced non - small - cell lung cancer ( NSCLC ) patients treated with Korean medicine . - pubmed
Methods : A retrospective review of medical records and FACT - G scores of patients with advanced NSCLC who received treatment with Korean medicine was conducted . - pubmed
Results : Of the 165 enrolled patients , 115 ( 70 % ) had extrathoracic metastasis and 139 ( 84 % ) had undergone prior anticancer treatment . - pubmed
After adjusting for age , sex , smoking history , ECOG - PS , histological type , and presence of extrathoracic metastasis , a high FACT - G total score ( hazard ratio ( HR ): 0.99 , p=0.032 ) and high PWB score ( HR : 0.94 , p < 0.001 ) were associated with prolonged survival as independent prognostic factors in patients with advanced NSCLC . - pubmed
Conclusion : The FACT - G total score and PWB score as HRQoL measurements were significant prognostic factors for survival in advanced NSCLC patients treated with Korean medicine . - pubmed
This finding implies that the FACT - G can be used in clinical practice as a predictor of survival in patients with advanced NSCLC . - pubmed
A new aggressive xenograft model of human colon cancer using cancer - associated fibroblasts . - pubmed
Almost half of the patients present recurrence within 5 years after the treatment of the primary tumor , the majority , with metastasis . - pubmed
The objective of this study was to identify an adequate animal model to study metastatic colon cancer and the application of new treatments . - pubmed
Methods : Human CAFs and normal fibroblasts ( NF ) for transplant and culture were obtained from surgical fresh samples of patients with adenocarcinoma of sigmoid colon . - pubmed
Conclusion : Our experiments demonstrate that cultured CAFs have a higher growth than NF and that when human CAFs are associated to human tumor cells , larger tumors with liver and lung metastases are generated than if only colon cancer cells with / without NF are transplanted . - pubmed
Here , we investigated the potential of ribavirin as a targeted anti - cancer agent in five human NPC cell lines . - pubmed
A training cohort used for diagnostic modelling included 30 patients with STEMI , 38 with stable angina ( SA ) and 30 matched - controls . - pubmed
Serum EV concentration from STEMI patients was increased as compared to controls and SA . - pubmed
EV biomarkers hold great potential as early markers for the management of patients with MI . - pubmed
Individuals with amnestic mild cognitive impairment ( aMCI ) have a high risk of developing Alzheimer ' s disease . - pubmed
Although repetitive transcranial magnetic stimulation ( rTMS ) is considered a potentially effective treatment for cognitive impairment in patients with aMCI , the neuroimaging mechanisms are poorly understood . - pubmed
Therefore , we performed a double - blind randomized sham - controlled trial in which rTMS was applied to the left dorsolateral prefrontal cortex of aMCI patients recruited from a community near the Third Hospital Affiliated to Sun Yat - sen University , China . - pubmed
Twenty - four patients with aMCI were randomly assigned to receive true rTMS ( treatment group , n = 12 , 6 men and 6 women ; age 65.08 + - 4.89 years ) or sham stimulation ( sham group , n = 12 , 5 men and 7 women ; age 64.67 + - 4.77 years ) . - pubmed
These findings suggest that high - frequency rTMS can effectively improve cognitive function in aMCI patients and alter spontaneous brain activity in cognitive - related brain areas . - pubmed
The effect of fermented Huyou juice on intestinal microbiota in a high - fat diet - induced obesity mouse model . - pubmed
This study mainly discussed the effect of fermented Huyou juice ( FHJ ) on modulating the intestinal microbiota of human , and anti - obesity mechanisms . - pubmed
Through the way of metagenomics , the effect of FHJ on gut flora has been summarized with a mice model of obesity induced by human flora - associated ( HFA ) high - fat diet . - pubmed
A Re - evaluation of the Taxonomy and Classification of the Type III Secretion System in a Pathogenic Bacterium Causing Soft Rot Disease of Pleurotus eryngii . - pubmed
Pantoea beijingensis , a gram - negative pathogenic bacterium , causes soft rot disease in the fungus Pleurotus eryngii in China . - pubmed
RESULTS : The mean age of first symptoms with Usher syndrome type IIa and nonsyndromic RP patients was 13.7 versus 29.8 years ( ocular phenotypes , p < 0.001 ) ; 17.7 versus 29.9 years ( nyctalopia , p < 0.001 ) ; 44.7 versus 54.8 years ( low vision based on VF , p < 0.001 ) ; 41.7 versus 54.7 years ( low vision based on VA , p < 0.001 ) ; and 46.0 versus 56.7 years ( legal blindness based on VF , p < 0.001 ) . - pubmed
The human gut - lung microbiota interplay provides a framework for therapies in the treatment and management of several pulmonary diseases and infections . - pubmed
were found in 38 % ( 319/829 ) of insulin - dependent diabetic patients , in 5 % ( 6/112 ) of insulin - independent diabetics , and in 1.7 % ( 3/177 ) of non - diabetic subjects . - pubmed
in patients with either diabetes of recent onset or longstanding disease . - pubmed
Reactivity of normotensive and spontaneously hypertensive rats ( SHR ) to some antihypertensive agents after acute and chronic treatment . - pubmed
Hypotensive action of some antihypertensive agents was studied on normotensive and spontaneously hypertensive rats in acute and chronic treatment . - pubmed
The reactivity of normotensive rats was much more weaker than in rats with spontaneous hypertension ( SHR ) . - pubmed
Three of the four patients had a significant decrease in visual acuity as the result of a retinopathy , primarily affecting the region about the macula accompanied by macular edema . - pubmed
Isolated , perfused , and ventilated rat lungs were challenged by paraquat ( 0.01 M ) in the presence of 2.5 mM Ca2 + , 2.5 mM Ca2 + with trifluoperazine ( 100 microM ) , 0.025 mM Ca2 + , or 0.025 mM Ca2 + with sodium metavanadate ( 10 microM ) to establish the effect of varying calcium concentration or calcium - dependent enzyme activities on injury induced by paraquat . - pubmed
These findings are discussed in relationship to some current and future uses of selectively bred animal strains and DD for studying the effects of alcohol . - pubmed
The primary role of imaging procedures in the preoperative staging of patients with bronchogenic carcinoma is to determine the need for further prethoracotomy assessment . - pubmed
Calcium infusion induced carcinoid symptoms in only two of six patients , which were associated with elevated 5 - HT levels ( whereas elevated SP levels were seen in only one patient ) . - pubmed
It appears that PG testing is superior to calcium infusion as a provocative test in patients with the carcinoid syndrome . - pubmed
Microvesicular steatosis of the liver was observed in some mice after 0.75 mmol / kg i.p . - pubmed
Microvesicular steatosis , however , requires very large doses in mice ( 0.75 mmol / kg i.p . - pubmed
The sera were titrated for complement fixing antibodies against cytomegalovirus ( Ad169 strain ) . - pubmed
Some strains of human immunodeficiency virus type 1 ( HIV-1 ) can infect primary monocytes and monocyte - derived macrophages in vitro . - pubmed
Prevalence of stephanofilariasis in young Bos indicus cattle in northern Australia . - pubmed
We studied B cell proliferation and differentiation in response to factors released by adherent monocytes in patients with systemic lupus erythematosus ( SLE ) . - pubmed
Nonimmune pigs passively immunized with monospecific swine serum to capsule were protected from lethal infection but not from development of hemorrhagic lung lesions , whereas pigs passively immunized with swine antiserum to live bacteria did not develop severe respiratory lesions . - pubmed
A case of peripheral ameloblastoma in the mandibular gingiva of a 42 - year - old man has been reported . - pubmed
Alveolar hemorrhage along with glomerulonephritis developed in a 31 - year - old black man . - pubmed
Application of an immunoprecipitation procedure to the study of SV40 tumor antigen interaction with mouse genomic DNA sequences . - pubmed
[ Ultrastructure of capillary permeability in human brain tumors . - pubmed
Using our modification of the vein patch technique , we created 16 aneurysms in the common carotid arteries of dogs . - pubmed
One human facial artery aneurysm was similarly treated . - pubmed
Because no experimental aneurysm models are yet physiological , our results must be applied with caution to human intracranial aneurysms . - pubmed
Intravenous injection of the extracts into healthy chickens showed that lethality of infected tissue extracts was higher than control extracts and was independent of the site of infection within the intestine . - pubmed
[ Changes in the estrus cycle in the estrus cycle of rats with alloxan diabetes ] . - pubmed
The course of an experimental liver fluke infection in the pig . - pubmed
Some structural aspects of carious lesions in human dentin . - pubmed
[ Time relationships of radiation - induced chromosome aberrations in humans ] . - pubmed
[ Coronary heart disease and hypertension in older workers of an industrial plant ] . - pubmed
The results of the experiments allow the conclusion that native crude fibres , as long as they remain in the normal range between 3 and 7 % in the ration does not cause a depression in the true digestibility of nitrogen and the amino acids in the feeding of fattening pigs . - pubmed
Immunoproliferative small intestinal disease in Basenji dogs : morphologic observations . - pubmed
Colestipol : a review of its pharmacological properties and therapeutic efficacy in patients with hypercholesterolaemia . - pubmed
Thus , like cholestyramine , colestipol is of benefit in patients with primary hypercholesterolaemia without associated hypertriglyceridaemia ( type IIa hyperlipoproteinaemia ) . - pubmed
[ Recovery from from Listeria monocytogenes meningitis in an adult ] . - pubmed
The authors describe a case of meningitis by Listeria monocytogenes from which the patient , an adult suffering from a chronic lymphatic leukosis , recovered completely . - pubmed
Two patients with systemic lupus erythematosus developed monarticular infectious arthritis , in which Neisseria meningitidis was recovered from knee synovial fluid . - pubmed
Two outbreaks of sternal wound infection due to organisms of the Mycobacterium fortuitum complex . - pubmed
Two outbreaks of postoperative wound infections due to organisms of the Mycobacterium fortuitum complex ( Mycobacterium chelonei and M. - pubmed
In one hospital , 19 of 80 patients who underwent cardiac surgery within a 10 - week period developed sternal infection with M. - pubmed
In the second hospital , four of nine patients who underwent cardiac surgery within a two - week period developed sternal incisional infection with M. - pubmed
Congenital tricuspidal insufficiency in two young beagle ( Cpb - DoBe67 ) dogs . - pubmed
Spontaneous peritonitis in a patient with cirrhosis of the liver and ascites . - pubmed
The syndrome of spontaneous peritonitis in patients with cirrhosis of the liver and ascites is discussed on the basis of a case history , with special reference to the diagnosis , pathogenesis and treatment of this syndrome . - pubmed
Morphological analysis of imprint histology and cytology was performed in 7 patients with yolk sac tumor ( YST ) . - pubmed
Polysaccharide - iron - regulated cell surface protein conjugate vaccine : its role in protection against Klebsiella pneumoniae - induced lobar pneumonia . - pubmed
Klebsiella pneumoniae has become an important cause of both community - acquired and nosocomial infections . - pubmed
It was found to be immunogenic and the protection afforded by the conjugate against the challenge strain was observed in a rat lobar pneumonia model . - pubmed
A four - drug combination chemotherapy with cisplatin , mitomycin , vindesine and 5 fluorouracile : a regimen associated with major toxicity in patients with advanced non - small cell lung cancer . - pubmed
The purpose of this study was to determine the activity of a 4 - drug combination chemotherapy : cisplatin , mitomycin C , vindesine and 5 - fluorouracil ( 5 - FU ) in patients with advanced non - small cell lung cancer ( NSCLC ) . - pubmed
Among 182 eligible patients , 75 % had received no prior therapy ; 41 % had locoregional disease and 59 % metastatic disease ; 41 % lost more than 5 % of their pretherapy body weight . - pubmed
Patients with locoregional disease had a significantly better response rate than those with metastases ( 44 % vs 27 % ) . - pubmed
A 33 - year - old right - handed woman had intractable simple and complex partial seizures ( SPS , CPS ) that began with global aphasia . - pubmed
Eight - seven acetabular fractures in eighty - seven patients underwent open reduction and internal fixation at Vanderbilt University Hospital from 1984 to 1989 . - pubmed
We evaluate the effects of chronic hypoxia on the metabolic phenotype of the muscle fiber types of humans . - pubmed
Chronic hypoxia appears to produce a shift from oxidative to glycolytic metabolism in those fibers which are typically the most aerobic in human muscle . - pubmed
Healing of foot ulcers in immunosuppressed renal transplant patients . - pubmed
Sixteen renal transplant patients were retrospectively studied to determine the time foot ulcerations healed . - pubmed
Six men ( average age , 42 ) underwent evaluation for idiopathic osteoporosis . - pubmed
The results suggest that idiopathic osteoporosis in these men is associated with increased parathyroid hormone secretion as assessed by increased renal cyclic adenosine monophosphate and high skeletal remodeling activity . - pubmed
In infants with gestational age & lt ; 29 weeks the risk for death in C. - pubmed
The outbreak was most likely a result of cross - infection because C. - pubmed
Unenhanced helical CT in patients with acute flank pain and renal infarction : the need for contrast material in selected cases . - pubmed
MATERIALS , PATIENTS AND METHODS : The incidence , clinical course and location of PBS in 97 operated women were studied for a 15 - year period . - pubmed
RESULTS : The incidence of PBS was 29 patients out of the 97 total . - pubmed
The syndrome was present for more than 48 months in eleven of these patients . - pubmed
In most cases the location of " phantom sensations " was the nipple ( 15 cases ) and the entire breast in five patients . - pubmed
In only three patients was phantom breast pain ( PBP ) reported whereas some discomfort was reported by the other patients . - pubmed
A comparison of tests to determine acuity deficits in children with amblyopia . - pubmed
Visual function was measured using pattern visual evoked potentials ( VEPs ) , the Cardiff test , and the Bailey - Lovie Chart in 21 visually normal children and 12 children with amblyopia . - pubmed
The Cardiff test identified five of the 12 children who were classified as amblyopic by the Bailey - Lovie test . - pubmed
Interocular VEP latency differences identified eight of the 12 children with amblyopia ; interocular VEP amplitudes correctly identified nine . - pubmed
BACKGROUND : Treatment of patients with malignant pleural effusions is mostly palliative . - pubmed
METHODS : Sixty patients with massive malignant pleural effusions were divided in 3 equal groups in a simple randomized manner . - pubmed
Patients with bone metastasis were evaluated repeatedly by bone scan at intervals of 3 - 6 months . - pubmed
Emergency tracheostomy often is needed in patients who have primary subglottic tumors or tumors than invade the subglottis . - pubmed
Aggressive local treatment is recommended in patients with subglottic lesions or subglottic tumor extension to prevent SR . - pubmed
We reviewed the histopathological diagnosis of human cytomegalovirus ( HCMV ) and the pathology of HCMV infection in immunocompromised hosts . - pubmed
Peripheral tears were made unilaterally in the medial menisci of seven goats in Group I and repaired with nonabsorbable suture . - pubmed
Correlation between humoral responses to human immunodeficiency virus type 1 envelope and disease progression in early - stage infection . - pubmed
Rupture and growth of adrenal myelolipoma in two patients . - pubmed
SAMPLE POPULATION : Skin of porcine cadavers . - pubmed
This study reviews , over a 5 - year period , the records of 70 consecutive patients with prosthetic knee infection and evaluates outcomes as a function of a staging system for prosthetic joint infection . - pubmed
Many of hypertensive individuals have glucose intolerance and dyslipidemia , and insulin resistance is common disorder on the basis of these diseases . - pubmed
Although generally thought of as a T cell - driven autoimmune disease , recent studies in experimental allergic encephalomyelitis ( EAE ) , the animal model of multiple sclerosis , suggest a significant role for innate immune mechanisms . - pubmed
Rat or human hepatoma cells in HEMA - MMA microcapsules lost viability within a week after implantation into an omental pouch in Wistar rats . - pubmed
Bacillus subtilis Bios11 strain was previously isolated and identified . - pubmed
When compared with lean rats , the rate of triglyceride synthesis in red muscle was 158 % higher in obese rats , and the rate of palmitate incorporation into diglycerides in white muscle was 93 % higher in obese rats . - pubmed
Pre- and postperfusion muscle triglyceride levels were higher in both red and white muscles of the obese rats . - pubmed
These results show that increased FA uptake and altered FA disposal to storage may contribute to the development of muscle insulin resistance in obese Zucker rats . - pubmed
We report a case of a 22 - year - old woman with relapsing polychondritis ( RP)--a rare and little known systemic autoimmune disease characterised by episodic inflammation of cartilaginous structures ( ear , nose , bronchi , trachea , larynx , ribs , cardiovascular system ) . - pubmed
The presence of anterior knee pain referable to the patella was 7.1 % ( five patients , six knees ) in Group A ( one patient with two knees had severe anterior knee pain ) and 9 % ( 13 knees in 13 patients ) in Group B. - pubmed
The population consisted of 10 consecutive patients with atrial tachycardia resistant to more than 2 drugs , 7 female , mean age 45 + /- 12 years . - pubmed
The histories of thirteen patients who presented with seizures secondary to benign intraaxial lesions treated by craniotomy and resection within the iMRI unit at our institution were reviewed . - pubmed
At follow - up , five patients had no seizures , 5 had rare seizures and the remaining 3 had worthwhile improvement in seizure frequency . - pubmed
METHODS : We studied 4,347 patients ( mean age , 61 + /- 12 years ; 2,230 men ) with known or suspected coronary artery disease by symptom - limited exercise echocardiography . - pubmed
Their hemagglutination capability with human erythrocytes was also tested , which was positive only for a few strains . - pubmed
Between August 1997 and October 1998 , 12 consecutive adult patients ( & gt;18 years ) with high - risk acute myeloid leukemia ( AML ) ( four patients in first early relapse , seven patients with secondary AML , and one patient with de novo AML concomitant to a lymphoproliferative disorder ) were enrolled to receive a single course of HY ( 100 mg / kg per day ) until bone marrow aplasia or for a maximum of 30 days . - pubmed
This study has demonstrated the safety and efficacy of HHY in inducing CR in AML patients with unfavorable prognosis . - pubmed
CONCLUSION : A complementary psychological treatment of patients suffering from CIU seems necessary , because of the high frequency of psychological symptoms . - pubmed
[ Innervation of the human gallbladder ; its changes in cholelithiasis ] . - pubmed
HOST - AGENT INTERACTION IN EXPERIMENTAL TUBERCULOSIS IN GUINEA PIGS , WITH SPECIAL REFERENCE TO THE EFFECTS OF BCG VACCINATION . - pubmed
The influence of unilateral nephrectomy on the development of stilboestrol - induced renal tumours in the male hamster . - pubmed
The effects of radiosurgery for metastatic brain tumors have been thought to be superior to fractionated radiotherapy due to high response and control rates , and patients showed improved quality of life although no prolongation of the life span was obtained . - pubmed
Community - based rehabilitation improves function of patients with traumatic brain injury . - pubmed
Myocardial , hepatic and renal damage resulting from para - aminobenzoic acid therapy ; observations in human cases and experimental animals . - pubmed
Two hundred and sixty patients with T1DM with and without diabetic microvascular complications , and 104 normal controls were recruited for this study . - pubmed
Feline immunodeficiency virus vectors for efficient transduction of primary human synoviocytes : application to an original model of rheumatoid arthritis . - pubmed
Because of the safety concerns raised by HIV vectors , we developed a gene delivery system derived from the ungulate lentivirus feline immunodeficiency virus ( FIV ) . - pubmed
A most recent large trial with Ginkgo biloba clearly showed that this drug does not prevent AMS in a low - risk setting in which acetazolamide in a low dose of 2 x 125 mg was effective . - pubmed
Serological responses from osteoarthritis ( OA ) patients and normal individuals to soluble proteins extracted from allografts were assessed using Western blotting and ELISA techniques . - pubmed
Antibodies were present in patients without the use of bone allografts , indicating that OA patients develop antibodies to bone soluble proteins . - pubmed
Soon to be published work from our laboratory has shown that ingestion of Perna canaliculus prevents the development of autoimmune diseases such as Systemic Lupus Erythematosus and rheumatoid arthritis in laboratory animals . - pubmed
Therefore , we xenografted subcutaneously into nude mice seven human colonic tumours ( from stages B1 to D ) that showed chromosome instability and transplanted them sequentially for up to 14 passages . - pubmed
The observation that some loci showed partial allelic imbalance in the initial tumour but loss of heterozygosity after the first passage in nude mice when all the normal cells were lost may allow identification of interesting genetic defects that could be involved in tumour expansion . - pubmed
A higher number of steps were climbed and a shorter time was taken to revert to the basal pulse rate ( recovery time ) by non - anemic girls compared to anemic girls ( P & lt ; 0.001 ) . - pubmed
METHODS : Five patients with MEWDS ( selected based on angiographic manifestations of the disorder ) were examined using slitlamp biomicroscopy and studied using fluorescein angiography and indocyanine green angiography . - pubmed
RESULTS : All 5 patients exhibited the newly recognized angiographic features termed dots and spots , which varied in size and location in the fundus . - pubmed
All patients exhibited other characteristics typical of MEWDS , including field loss and foveal granularity . - pubmed
METHODS : Sixty - two patients with low rectal cancer underwent low anterior resection and total mesorectal excision ( TME ) . - pubmed
Five patients with microscopic tumor nodule spread in the CRM observed in the study suggested that microscopic metastases exist in pelvic lateral areas and in the mesorectum simultaneously , indicating the significance of preoperative and/or postoperative radiochemotherapy . - pubmed
Microvessel density in the placental bed among preeclampsia patients . - pubmed
CONTEXT AND OBJECTIVE : Morphological changes in the spiral arteries of the placental bed have been studied in patients with preeclampsia , one of the largest causes of maternal and perinatal morbidity and mortality . - pubmed
RESULTS : Biopsies containing spiral arteries were obtained from 34 hypertensive pregnant women with proteinuria , and 26 normotensive pregnant women . - pubmed
These alpha - galacto - oligosaccharides ( alpha - GOS ) , which are found in large quantities in vegetables , such as soy , can cause gastrointestinal disorders in sensitive individuals because monogastric animals ( including humans ) do not posses alpha - Gal in the gut . - pubmed
PURPOSE : Clearance of mucus from airways is the cornerstone of therapy for lung disease in patients with cystic fibrosis ( CF ) . - pubmed
The Frequencer induced airway clearance in patients with CF that was equivalent to that of CCPT . - pubmed
CONCLUSIONS : These results indicate the Frequencer is safe and as effective as CCPT in inducing airway clearance in patients with CF . - pubmed
The effect of melatonin on endotoxemia - induced intestinal apoptosis and oxidative stress in infant rats . - pubmed
The animals were randomized into three experimental groups : ( 1 ) controls ; ( 2 ) endotoxemia ; ( 3 ) endotoxemia treated with melatonin ( 10mg / kg ) . - pubmed
The administration of melatonin into endotoxemic rats prevented the increase in the TBARS levels , and increased the activities of antioxidant enzymes and attenuated apoptotic cell death in both intestinal epithelium and lamina propria . - pubmed
CONCLUSIONS : Melatonin diminished the intestinal oxidative stress and apoptotic damage induced by endotoxemia in infant rats . - pubmed
Despite the large resource of transgenic and knockout mice harboring mutations relevant to skin disorders , few organotypic mouse skin models are available . - pubmed
Limbic structures are prone to age - related impairments in proteasome activity and neuronal ubiquitinated inclusions in SAMP10 mouse : a model of cerebral degeneration . - pubmed
Invasive fungal infection in severely immunosuppressed patients with acute myelogenous leukemia ( AML ) remains a serious challenge because ( a ) of the higher rates of non - drug susceptible fungal sinopulmonary disease ; ( b ) despite advances in diagnostic fungal assays , the correct identification of causative organism(s ) is difficult , and antifungal drug susceptibility data are seldom available during clinical decision making ; and ( c ) the increasing frequencies of zygomycosis , scedosporiosis , and highly virulent Candida tropicalis infection have undermined the gains attributed to effective anti - Aspergillus drug therapy . - pubmed
Sixty percent of the patients who presented with leukocoria had congenital cataract ( 18 % unilateral and 42 % bilateral ) . - pubmed
Leukocoria in children demands immediate attention because a significant number of children have pathology that either threatens life or causes permanent visual disability . - pubmed
We present the case of a 28 - year - old woman at 25 weeks of gestation diagnosed with Stage 1B cervical cancer . - pubmed
Double infection of tobacco protoplasts with brome mosaic virus and cowpea chlorotic mottle virus . - pubmed
Mixed infections of tobacco protoplasts with Cowpea chlorotic mottle virus ( CCMV ) and brome mosaic virus ( BMV ) have been studied . - pubmed
, BMV dominated in mixed infections and prevented synthesis of infectious CCMV . - pubmed
Healthy protoplasts could be infected after several hours in culture but the susceptibility to infection decreased with time in culture ; the decrease was much faster with BMV than with CCMV , probably because the difference in electrical charge of the two viruses affects the method of entry into the protoplasts . - pubmed
If inoculation with the second virus was delayed there was an increasing resistance to superinfection ( interference or cross - protection ) so that when the delay between inoculations was more than 8 hr BMV was no longer able to infect protoplasts previously infected with CCMV and vice versa . - pubmed
Attempts to rescue a temperature - sensitive strain of CCMV with BMV under restrictive conditions ( 35 degrees ) were unsuccessful ; dominance by BMV prevented synthesis of infectious CCMV RNA . - pubmed
The quality of the starting material is highly guaranteed for blood derivatives due to the individual screening for specific markers ( antigens , genome , antibodies ) for major blood borne viruses such as hepatitis B and C viruses ( HBV , HCV ) and human immunodeficiency virus ( HIV ) . - pubmed
BACKGROUND : This study examines the clinical , echocardiographic , surgical , and pathologic features of patients who had heart valve operations for combined congenital bicuspid aortic valve and mitral regurgitation due to degenerative disease of the mitral valve . - pubmed
METHODS : A retrospective review of 1595 patients who had procedures for mitral regurgitation due to degenerative disease of the mitral valve and 1820 patients who had procedures for congenital bicuspid aortic valve disclosed 29 patients who had combined diseases . - pubmed
Mitral regurgitation in 21 of 29 patients was caused by prolapse of the anterior leaflet , which was exceptionally large ( mean height , 36.5 + /- 6.6 mm ) . - pubmed
The bicuspid aortic valve was incompetent in 19 of 21 , and the aortic annulus exceeded 30 mm in 20 of 21 patients . - pubmed
CONCLUSIONS : Patients with combined mitral regurgitation due to myxomatous degeneration and bicuspid aortic valve disease who require operations often have a large , prolapsing anterior leaflet of the mitral valve and dilated aortic annulus with aortic insufficiency due to cusp prolapse . - pubmed
Commentary : Below - the - ankle subintimal angioplasty : how far can we push this application for lower limb preservation in diabetic patients ? - pubmed
PURPOSE : Patients with advanced gastric or gastroesophageal adenocarcinoma need more efficacious and safer treatments than established today . - pubmed
One thousand fifty - three patients were stratified ( center , number of metastatic sites , prior adjuvant therapy , and measurable cancer ) and randomly assigned . - pubmed
The primary end point was superiority in overall survival ( OS ) from cisplatin / S-1 compared with cisplatin / infusional fluorouracil in patients with advanced , untreated gastric , or gastroesophageal adenocarcinoma . - pubmed
CONCLUSION : Cisplatin / S-1 did not prolong OS of patients with advanced gastric or gastroesophageal adenocarcinoma compared with cisplatin / infusional fluorouracil , but it did result in a significantly improved safety profile . - pubmed
The offspring of an individual with any of the subtypes of CMT1 have a 50 % chance of inheriting the altered gene . - pubmed
OBJECTIVES : To investigate the impact of different definitions on the frequency of benign multiple sclerosis ( MS ) in patients with a long follow - up , and to study the presence of non - motor symptoms and employment across the definitions . - pubmed
These results suggest that maintaining genome stability by heterochromatin formation and correct chromosomal packaging is essential for normal cellular functions and for survival of animals under genotoxic stress . - pubmed
The effect of succinate on pentobarbital toxicity and narcosis in the cat . - pubmed
Over the last two decades multiple studies have demonstrated an increased incidence of additional malignancies in patients with intraductal papillary mucinous neoplasms ( IPMNs ) . - pubmed
CASE SUMMARY : we report a 25 - year - old woman presenting with sudden onset of vertigo , hoarseness , dysphagia , right facial numbness , and proximal quadriparesis . - pubmed
INTRODUCTION : Vitamin K antagonists ( VKAs ) are the main therapeutic agents used to prevent embolic events in patients with atrial fibrillation ( AF ) . - pubmed
Hippoglossus hippoglossus with the gaping - jaw malformation , common in intensively cultured individuals of this species , were examined histologically . - pubmed
BACKGROUND AND OBJECTIVE : To report on a new surgical technique for neovascular glaucoma ( NVG ) in patients with proliferative diabetic retinopathy or retinal vein occlusion . - pubmed
To maintain an IOP of less than 21 mm Hg without anti - glaucoma medications , surgical revisions of the filtration site are necessary in at least 50 % of patients . - pubmed
We have previously shown that human sleep - wake stage distributions exhibit multi - exponential dynamics , which are fragmented by obstructive sleep apnea ( OSA ) , suggesting that Markov models may be a useful method to quantify architecture in health and disease . - pubmed
BACKGROUND : Two vaccines against human papillomavirus ( HPV ) , a necessary cause of cervical cancer , are currently licensed and recommended for routine administration in the U.S. to girls in a three - dose series . - pubmed
We did not find a higher morbidity or mortality in patients with a more severe liver damage measured by the CASH score . - pubmed
We report the frequency and effectiveness of patient - initiated epilation and its relationship to corneal opacity . - pubmed
The presence of Plus disease was identified by the non - ophthalmologist and results compared to the clinical examination by a pediatric ophthalmologist experienced in ROP detection and treatment . - pubmed
Hepatoportal sclerosis in childhood : some presenting with cholestatic features ( a re - evaluation of 12 children ) . - pubmed
Between 1999 and 2009 , 12 children diagnosed with HPS were retrospectively evaluated . - pubmed
Histopathologically , all patients had hepatoportal sclerosis / intimal fibrous thickening of portal vein and periportal fibrosis , acinar transformation , and regenerative nodules not surrounded by fibrous septae . - pubmed
Eight patients had vascular aberrations , 7 had ductular reaction , 1 showed mild cholangitis , and 1 had canalicular bile pigment . - pubmed
Cytotoxicity tests were implemented on MCF-7 Human breast cancer cell line for the investigation of drug and polymer toxicity . - pubmed
Effects of bone marrow mesenchymal stem cells in a rat model of myocardial infarction . - pubmed
METHODS : MI was induced in 21 Sprague - Dawley rats by ligation of the left anterior descending artery . - pubmed
CONCLUSIONS : MSCs can differentiate into beating cardiomyocytes in a rat model of MI and improve myocardial function . - pubmed
Bone metastasis is a common incurable complication of breast cancer affecting around 70 % of patients with advanced disease . - pubmed
In order to improve outcomes for these patients , the cellular and molecular mechanisms underlying bone metastasis need to be established . - pubmed
Tumour growth in bone was initiated by intra - cardiac inoculation of MDA - MB-231 - GFP breast cancer cells in immunocompromised mice . - pubmed
CONCLUSIONS : Pacific people in New Zealand have a disproportionate cancer burden related to infectious diseases such as HPV and Hepatitis B. However , with escalating evidence for causal associations between diabetes , obesity , and physical inactivity with various cancers , the challenge will be to prevent these cancers from rising in Pacific people who have the highest rates of these conditions in New Zealand . - pubmed
Disparities for tobacco - related cancers support tobacco consumption as another important cause of cancer incidence disparity . - pubmed
METHODS : Hypertrophic scar samples were collected from 42 patients with hypertrophic scar for 1 - 20 years ( mean , 4.5 years ) , including 15 males and 27 females with an average age of 32.6 years ( range , 16 - 50 years ) . - pubmed
Scaffold - free adipose - derived stem cells ( ASCs ) improve experimentally induced osteoarthritis in rabbits . - pubmed
METHODS : OA was induced in adult white New Zealand rabbits by unilateral anterior cruciate ligament transection ( ACLT ) ; the contralateral knee was considered the sham - operated group . - pubmed
This case report presents a young 30 - year old male patient with type 1 diabetes mellitus , who was treated for hypoglycemia and a general bad feeling . - pubmed
Reinforcing properties of Pramipexole in normal and parkinsonian rats . - pubmed
While parkinsonian were slower than sham rats in acquiring self - administration behavior , they later reached the same level of intake . - pubmed
A neonatal model of intravenous Staphylococcus epidermidis infection in mice & lt;24 h old enables characterization of early innate immune responses . - pubmed
Staphylococcus epidermidis ( SE ) causes late onset sepsis and significant morbidity in catheterized preterm newborns . - pubmed
Current murine models of neonatal bacterial infection employ intraperitoneal or subcutaneous routes at several days of age , and may , therefore , not accurately reflect distinct features of innate immune responses to bacteremia . - pubmed
Long - term changes of diffusion tensor imaging and behavioural status after acupuncture treatment in rats with transient focal cerebral ischaemia . - pubmed
A study was undertaken to assess its effects in rats with transient middle cerebral artery occlusion ( tMCAO ) and discuss its mechanisms . - pubmed
CONCLUSIONS : The acupuncture points applied were effective , and improving neuronal regeneration may have a role in the mechanism of acupuncture treatment of post - stroke paralysis of the limbs in rats . - pubmed
CONCLUSIONS : There was no significant difference in the presence of NAFLD between AI patients and controls . - pubmed
Effect of different levels of supplemental yeast on body weight , thyroid hormone metabolism and lipid profile of broiler chickens . - pubmed
The present study examined the effect of supplemental yeast probiotic preparations on body weight , thyroid hormone metabolism and serum lipid profile in broilers . - pubmed
Chickens fed 2.0 % probiotic had a significantly ( P<0.05 ) higher body weight when compared with the control group . - pubmed
In conclusion , supplementing broiler feeds with a yeast probiotic increased body weight , enhanced thyroid hormone metabolism , and decreased cholesterol and lipoproteins in broiler chickens . - pubmed
Titanium oxide nanoparticle instillation induces inflammation and inhibits lung development in mice . - pubmed
Titanium oxide ( TiO ( 2 ) ) nanoparticles , which are commonly used in cosmetics , sunscreens , paints , and food , have been shown to induce emphysema and lung inflammation in adult mice . - pubmed
We hypothesized that exposure of newborn mice to TiO ( 2 ) would induce lung inflammation and inhibit lung development . - pubmed
METHODS : We used a validated atlas registration to locate and stimulate through electrode contacts in D - STN and V - STN regions of 37 people with Parkinson ' s disease . - pubmed
RESULTS : Internalizing and externalizing problems were significantly represented among children with headaches compared to the control group , respectively 63 % and 27 % , without significant differences between migraine and tension - type headache children . - pubmed
These in vitro results suggest CGMP , LB , EPS and WB as good candidates to be included in piglet 's diet with supported functional activity against colibacillosis . - pubmed
In this study , canine AD - MSCs ( cAD - MSCs ) were individually isolated from five dogs and subjected to proliferative culture with seven sub - passages . - pubmed
OBJECTIVE : The aim of this study based on the records of the dermatology department of a tertiary referral hospital was to describe patients treated for allergic contact dermatitis induced by nickel between 2000 and 2010 . - pubmed
MATERIALS AND METHODS : From records of the skin allergy section of the dermatology department we extracted and analyzed information for patients who underwent patch testing with the standard series of the Spanish Contact Dermatitis Research Group ( GEIDAC ) , which includes a patch with 5 % nickel sulfate in petroleum jelly . - pubmed
However , the contact dermatitis could be attributed to nickel in only 57 of the 824 patients ( 6.9 % ) who showed sensitization to nickel . - pubmed
This test is even useful for identifying the specific object responsible for a patient 's dermatitis . - pubmed
CONCLUSIONS : Ustekinumab 45 and 90 mg treatments significantly inhibited radiographic progression of joint damage in patients with active PsA. - pubmed
HFD - fed CatE(-/- ) mice displayed reduced body weight gain and defective development of white adipose tissue ( WAT ) and brown adipose tissue ( BAT ) , compared with HFD - fed wild - type mice . - pubmed
Moreover , fat - induced CatE(-/- ) mice showed abnormal lipid accumulation in non - adipose tissues characterized by hepatomegaly , which is probably due to defective adipose tissue development . - pubmed
Detailed pathological and biochemical analyses showed that hepatomegaly was accompanied by hepatic steatosis and hypercholesterolemia in HFD - induced CatE(-/- ) mice . - pubmed
The work is devoted to the description of neurological , vestibulometric and audiologic data obtained in the examination of 11 patients with basilar type migraine . - pubmed
We report a case of severe hypertriglyceridemia - induced acute pancreatitis in a 24 - year - old woman caused by Estrostep , occurring nearly 10 years after she began using the drug . - pubmed
We previously reported that synthetic flavonoid dimers have potent antipromastigote and antiamastigote activity against Leishmania donovani , the causative agent of visceral leishmaniasis . - pubmed
One of the flavonoid dimers ( compound 39 ) has marked antipromastigote ( 50 % inhibitory concentrations [ IC50s ] , 0.19 to 0.69 muM ) and antiamastigote ( IC50s , 0.17 to 2.2 muM ) activities toward different species of Leishmania that cause cutaneous leishmaniasis , including Leishmania amazonensis , Leishmania braziliensis , Leishmania tropica , and Leishmania major . - pubmed
In the mouse model of cutaneous leishmaniasis induced by subcutaneous inoculation of L. - pubmed
amazonensis in mouse footpads , intralesional administration of 2.5 mg / kg of body weight of compound 39.HCl can reduce footpad thickness by 36 % , compared with that of controls values . - pubmed
The authors performed repeated surgeries and small bowel resections on a patient classified to stage number three on Bell scale due to necrotizing enterocolitis . - pubmed
In vivo imaging showed significantly higher fluorescence intensity in OA knees compared to sham - operated ( control ) knees of the same mice . - pubmed
BACKGROUND AND OBJECTIVES : New therapeutic protocols for patients with end - stage Parkinson disease include a carbidopa / levodopa combination using continuous , modulated enteral administration via a portable pump . - pubmed
RESULTS : Five patients with end - stage Parkinson disease were referred to our department after successful therapeutic testing with administration of levodopa / carbidopa via naso - jejunal tube . - pubmed
PATIENTS AND METHODS : The study included 67 children with chronic hepatitis B and 99 healthy controls . - pubmed
The hepatitis B patients were divided into immuntolerant , chronic inactive , and treatment groups according to their laboratory findings . - pubmed
Loudness dependence of auditory evoked potentials ( LDAEP ) in clinical monitoring of suicidal patients with major depression in comparison with non - suicidal depressed patients and healthy volunteers : A follow - up - study . - pubmed
Twenty patients ( mean age 43.25 + - 10.85 , age range 20 - 61 , 11 male ) suffering from a major depressive episode who had either acutely attempted suicide or who had suicidal plans and behavior , which are reflected by item 3 of Hamilton Depression Rating Scale & gt;= 3 ( suicidality ) , were included in the study . - pubmed
Correction : Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis . - pubmed
In individuals with histamine intolerance ( HIT ) ingestion of food with normal contents of histamine causes histamine - mediated symptoms . - pubmed
A newly isolated strain , CWD-67 , which exhibited high fibrinolytic activity , was screened from dumping soils enriched with poultry wastes . - pubmed
The strain was identified as Bacillus tequilensis ( KF897935 ) by 16Sr RNA gene sequence analysis and biochemical characterization . - pubmed
A new method for the detection of cancer using 1 mul of human serum , attenuated total reflection - Fourier transform infrared spectroscopy and pattern recognition algorithms is reported using a 433 patient dataset ( 3897 spectra ) . - pubmed
METHODS : Data from 246 women with phyllodes tumors of the breast treated in the Cancer Hospital , Chinese Academy of Medical Sciences between January 2002 and December 2012 , were collected and analyzed retrospectively . - pubmed
56 patients had local recurrence , 5 patients had distant metastasis , while one case had both local recurrence and distant metastasis . - pubmed
Type of primary surgery , fibroadenoma history and histological type are independent factors predicting the disease - free survival of patients with phyllodes tumors of the breast . - pubmed
The incidence of infection , sepsis , and multiple organ dysfunction syndrome ( MODS ) and the mortality of patients were recorded during 2 months after injury . - pubmed
RESULTS : The 5 - year survival rate in our series was 45 % , and this percentage increased to 65 % when patients with advanced stage cancer ( stage IIIb or higher ) were excluded . - pubmed
We achieved cancer - free margins in 19 patients ( 60 % ) . - pubmed
Cognitive reserve and cognitive performance of patients with focal frontal lesions . - pubmed
This study reports the rates of RNFL thinning over the 6 x 6 mm2 RNFL thickness map and their application for indication of visual field ( VF ) worsening in patients with glaucoma . - pubmed
Objective : To investigate the association between the rates of RNFL thinning and the risk of VF worsening in patients with glaucoma . - pubmed
Delayed diagnosis of shunt overdrainage following functional hemispherotomy and ventriculoperitoneal shunt placement in a hemimegalencephaly patient . - pubmed
The condition presents a diagnostic challenge particularly in patients with cognitive impairment and developmental delays . - pubmed
Here we present a 3 - year - old boy with drug - resistant focal onset seizures due to hemimegalencephaly who previously underwent functional hemispherotomy followed by ventriculoperitoneal shunt placement for postoperative hydrocephalus . - pubmed
Vascular Anatomy Predicts the Risk of Cerebral Ischemia in Patients Randomized to Carotid Stenting Versus Endarterectomy . - pubmed
Differential Recognition of Mycobacterium tuberculosis - Specific Epitopes as a Function of Tuberculosis Disease History . - pubmed
OBJECTIVES : We hypothesized that the repertoire of Mtb - derived epitopes recognized by T cells from individuals with latent Mtb infection differs as a function of previous diagnosis of active TB disease . - pubmed
MEASUREMENTS AND MAIN RESULTS : We identified a set of " type 2 " T - cell epitopes that were recognized at 10 - fold - lower levels in Mtb - infected individuals with a history of TB disease less than 6 years ago than in those without previous TB . - pubmed
CONCLUSIONS : Preferential loss of T - cell reactivity to Mtb epitopes that are homologous to bacteria in the microbiome in persons with previous TB disease may reflect long - term effects of antibiotic TB treatment on the microbiome . - pubmed
We evaluated the effectiveness of Tc-99 m ECD SPECT in assessing circulatory insufficiency in the brains of patients with antiphospholipid antibodies and neuropsychiatric symptoms but without thromboembolism . - pubmed
MATERIALS AND METHODS : Patients with a history of positive antiphospholipid antibodies and neuropsychiatric symptoms composed the case group ; patients without antiphospholipid antibody served as the control group . - pubmed
Tumor stage in patients operated for rectal cancer : a comparison of the pre - operative MR and the resection specimen , with specific attention to the effect of neo - adjuvant radiotherapy . - pubmed
METHODS : Patients diagnosed with rectal cancer ( 2002 - 2015 ) and a pre - operative MR were included . - pubmed
Underestimation as well as overestimation of the tumor occurred both in the patients treated with radiotherapy as well as those who underwent immediate operation . - pubmed
Transcranial Magnetic Stimulation as an Additional Diagnostic Tool in Children with Acute Inflammatory Demyelinating Polyneuropathy . - pubmed
SUBJECTS AND METHODS : Twenty healthy children ( 7 - 14 years old ) without signs of neurological disorders were enrolled as controls . - pubmed
Thirty - seven patients ( 8 - 13 years old ) with AIDP were enrolled as the main group . - pubmed
RESULTS : Significant differences between children with AIDP and controls on latencies of both cortical and lumbar MEPs were registered . - pubmed
High - dose Vit C has been investigated as a treatment for cancer patients since the 1969 . - pubmed
Despite many treatment options for gout , there is a substantial need for alternative treatments for patients unresponsive to current therapies . - pubmed
Complete surgical resections are crucial for permanently curing patients with gastrointestinal stromal tumors ( GISTs ) . - pubmed
Non - exposed endoscopic wall - inversion surgery ( NEWS ) for patients with gastric GISTs is a novel , minimally invasive surgical technique that may aid in complete resection of the tumor margin by endoscopy and laparoscopy methods , removing the whole layer of the gastric wall and the entire tumor , with decreased risk of peritoneal contamination or tumor spread to the peritoneum . - pubmed
To the best of our knowledge , the present study reports the first use of NEWS for a patient with small gastric GIST in Thailand . - pubmed
Information on HIV status is available in 63 % of cases , of which 7 % were HIV - positive . - pubmed
Nephrotoxic effects of Valeriana wallichii . - pubmed
Therefore , the current study was undertaken in an attempt to increase the use of these drugs without causing nephrotoxicity by exploring the nephroprotective effects of a medicinal plant with high flavonoid contents and strong antioxidant properties , namely Valeriana wallichii . - pubmed
The study group included patients with surgically confirmed anastomotic leaks ( n = 59 ) , and the control group included patients without anastomotic leaks ( n = 48 ) confirmed by either repeat surgery or uneventful clinical follow - up for at least 6 months . - pubmed
BACKGROUND : To achieve the World Health Organization hepatitis C virus ( HCV ) elimination targets , it is essential to increase access to treatment . - pubmed
One thousand patients with unilateral hip disarticulation , trans - femoral amputation and knee disarticulation due to war - related injuries were invited to undergo a thorough physical examination . - pubmed
The findings may be useful to adopt new strategies in planning rehabilitation programs to improve quality of life and health status of patients with war - related lower limb amputation . - pubmed
CRISPR - based technologies have promise as a therapeutic platform for many human genetic diseases previously considered untreatable , providing a flexible approach to high - fidelity gene editing . - pubmed
Materials and Methods : A cohort of Medicare - eligible patients discharged with the Diagnosis - Related Group ( DRG ) codes 480 to 482 ( hip and femur fractures requiring surgical fixation ) from a level 1 trauma center between October 2014 and September 2016 was evaluated and assigned a trauma triage risk score ( STTGMA score ) . - pubmed
EXPERT OPINION : The treatment of hemophilia A with inhibitors by induction of immunotolerance and using by - passing concentrates , improved the quality of life of patients but did not allow them to have a life expectancy like that of patients without inhibitors . - pubmed
Increased incidence of community - associated Staphylococcus aureus bloodstream infections in Victoria and Western Australia , 2011 - 2016 . - pubmed
CAR T - Cell Therapy in Non - Hodgkin Lymphoma Patients . - pubmed
Background / Objective : Although microRNA ( miRNA)-directed regulation of bovine tuberculosis ( bTB ) has already been reported , very little is known about the incited pathways and genes . - pubmed
It goes on to argue about its role as agents of domination of limitless profit interests and as an expression of the power of the health industry , justifying itself with the proposal of alternatives tending to overcome that network : transdisciplinarity and the concept of organism as hierarchical totality and interacting with its environment , with respect to disjunction and reductionism ; the cultural history of the disease in relation to the health - disease binomial and the dehumanizing technologization ; good living , the search for spiritual , intellectual , moral and coexistence growth as meaning of human life , as an alternative to the medicalization and antidote of degrading traits and stimulating medicine of the endogenous healing forces of the organism whose foundation of possibility and credibility is the placebo effect as an alternative to suppressive therapy for non - communicable chronic conditions , based on the pharmacological effect with unfailing side effects . - pubmed
IgG4 - related disease in patients with newly diagnosed idiopathic retroperitoneal fibrosis : a population - based Danish study . - pubmed
Individuals with substance use disorders ( SUDs ) have to cope with drug - related cues and contexts which can affect instrumental drug seeking , as shown with Pavlovian - to - instrumental transfer ( PIT ) tasks among humans and animals . - pubmed
Identification of pre - diabetic individuals with decreased functional ss - cell mass is essential for the prevention of diabetes . - pubmed
At the latest follow - up , the correction of cubitus varus obtained was satisfying in the five cases of our series and all the patients had pain free elbow mobility . - pubmed
Ulnar nerve palsy complicated the evolution in one patient , which fully recovered within 6 months . - pubmed
Patients were included if they were between 20 and 80 years old and had a serum uric acid ( sUA ) level > = 7.0 mg / dl with or without gout , estimated glomerular filtration rate ( eGFR ) of 15 - 60 ml / min/1.73 m2 , and urinary protein creatinine ratio ( uPCR ) of 0.15 - 3.5 g / gCr . - pubmed
Antigen - shift in varicella - zoster virus - specific T - cell immunity over the course of Fingolimod - treatment in relapse - remitting multiple sclerosis patients . - pubmed
Analyzed samples comprised of different groups including 18 patients with RRMS at baseline ( BL ) , 6 and 12 months after FTY - treatment start , 12 patients with long - term ( LT ) FTY - treatment , one FTY - treated patient , before and after VZV - reactivation . - pubmed
However , VZV - specific immunity could be detected in the majority of RRMS patients throughout FTY - treatment with increasing prevalence after 6 months of treatment . - pubmed
CONCLUSION : Monitoring VZV - specific T - cell immunity might provide a valuable tool to RRMS patient risk management during FTY - treatment . - pubmed
Pharmacotherapy combined with psychotherapy treatments for gambling disorder may provide better rates of patient retention in comparison to pharmacology - only treatments , though further research is needed in this area . - pubmed
Over the past decade , human stem cell - derived brain organoids have emerged as a biologically relevant model system to study normal human brain development and neurological diseases . - pubmed
The diagnosis of EBV - associated lymphoproliferative disorder ( LPD ) was demonstrated by elevation of the plasmatic EBV viral load . - pubmed
Screening diversity and distribution of Copia retrotransposons reveals a specific amplification of BARE1 elements in genomes of the polyploid Hordeum murinum complex . - pubmed
RESULTS : Of the 23 Arab patients with a median age of 64 years ( range , 36 - 87 years ) , eight had hepatocellular carcinoma , four had cholangiocarcinoma , and 11 had liver - only or liver - dominant metastases from other primary cancers . - pubmed
The mouse optic nerve crush ( ONC ) model has been widely used to study optic neuropathies and central nervous system ( CNS ) axon injury and repair . - pubmed
Previous histological studies of retinal ganglion cell ( RGC ) somata in retina and axons in ON demonstrate significant neurodegeneration after ONC , but longitudinal morphological and functional assessment of RGCs in living animals is lacking . - pubmed
are susceptible to infection by many plant - parasitic nematodes , including Meloidogyne incognita . - pubmed
We then conducted a group study on a dataset of in vivo MRI from temporal lobe epilepsy ( TLE ) patients and healthy controls . - pubmed
The method detected local thinning patterns in patients , predominantly ipsilaterally to the seizure focus , which is consistent with medical knowledge . - pubmed
It shows good robustness with respect to anisotropy and inter - rater variability and has the potential to detect local atrophy in patients . - pubmed
A total of 282 patients were included , of whom 56 had brain metastases that were treated with upfront local radiation therapy in 80.3 % of cases . - pubmed
The overall response rate was 39.2 % and 44.4 % in patients with and without brain metastases ( P=0.48 ) , respectively , while intracranial response rate and intracranial disease control rate were 67.5 % and 85.0 % , respectively . - pubmed
Drug discontinuation rate due to treatment - related adverse events was 10.7 % and 10.2 % in patients with and without brain metastases , respectively . - pubmed
In patients with brain metastases , only PS > = 2 was predicted for a worse TTF ( P=0.02 ) and OS ( P=0.03 ) . - pubmed
Presence of brain metastases per se does not appear to be prognostic , and PS > = 2 seems to be the only factor associated with a worse outcome in patients with brain metastases . - pubmed
The Effect of Peppermint ( Mentha piperita ) Extract on the Severity of Nausea , Vomiting and Anorexia in Patients with Breast Cancer Undergoing Chemotherapy : A Randomized Controlled Trial . - pubmed
Background and Objective : Nausea , vomiting , and anorexia are the most common side effects reported in cancer patients undergoing chemotherapy . - pubmed
The present study aimed to determine the effect of peppermint extract on the severity of nausea , vomiting , and anorexia in patients with breast cancer undergoing chemotherapy . - pubmed
Methods and Materials : In this randomized controlled trial , we selected 84 patients with breast cancer undergoing chemotherapy . - pubmed
Conclusion : The use of peppermint as a method in complementary medicine may improve nausea , vomiting , and anorexia in patients with breast cancer undergoing chemotherapy . - pubmed
Meta - analysis of the effect of vascular complications on mortality in patients undergoing femoral venoarterial extracorporeal membrane oxygenation . - pubmed
BACKGROUND : Extracorporeal membrane oxygenation ( ECMO ) has become an accepted treatment modality in the management of select patients with cardiopulmonary failure . - pubmed
Increased GNRB risk in auto - HSCT patients transplanted for autoimmune diseases is worrying . - pubmed
METHODS : We identified 176 PET - positive PANs on pretreatment PET / CT of 47 patients with diagnosed FIGO stage IB - IVA cervical cancer . - pubmed
The children were observed for verbal , vocal , facial , and motor behavior during diphtheria - pertussis - tetanus or diphtheria - tetanus injections . - pubmed
The children then rated the extent of pain during the injection by responding to two instruments , a modification of Eland 's Projective Tool and Hester 's Poker Chip Tool . - pubmed
[ Melanoma of the choroid in young patients ] . - pubmed
Of the four types of lesions treated , verruca vulgaris , condyloma acuminatum , and tattoos responded best . - pubmed
Radiographs an patient histories of 36 children were examined in order to determine radiological signs that would allow a prediction or an early diagnosis of the aseptic necrosis of the femur head nucleus ( Luxations - Perthes ) during the treatment of hip dysplasia . - pubmed
Necrosis of the nucleus appeared in 17 joints ( of 15 children ) . - pubmed
The effects , in adult animals , of limbic lesions produced in infancy were studied in 273 male Wistar rats using weight gain and conditioned emotional response ( CER ) and conditioned avoidance response ( CAR ) acquisition as the critical measures . - pubmed
In all 3 children there was a delay in diagnosis , and it is suggested that a chronic intussusception should be considered more frequently in children with persistent abdominal symptoms for which no cause can be found . - pubmed
[ Experimental infection with hepatitis E virus in rhesus monkeys ] . - pubmed
An experimental model of hepatitis E was established in Rhesus Monkeys . - pubmed
Four animals were inoculated with stool suspensions that obtained from patients with hepatitis E. - pubmed
After 4 - 6 weeks the ALT of the four animals infected HEV raised 3 - 4 times and the live biopsy showed acidophilic degeneration of hepatocytes and coagulative liver cell necrosis . - pubmed
The case of a 71 - year - old woman with acute myelomonocytic leukaemia and severe pains in her arms , legs and back during treatment is described . - pubmed
The condition should be suspected whenever inexplicable pain problems and signs of peripheral neuropathy occur in patients with acute leukaemia . - pubmed
Metabolic alkalosis and the response of the trout , Salmo fario , to acute severe hypoxia . - pubmed
Trout ( Salmo fario ) were acutely transferred from seawater to freshwater in order to induce blood metabolic alkalosis ( cf . - pubmed
The results demonstrate that initial blood alkalosis does not prevent the typical physiological responses of trout to hypoxia but simply shifts to lower PaO2 values the threshold at which these responses begin . - pubmed
Hypophosphatemic vitamin D - resistant rickets is the most common form of vitamin D - resistant rickets in man . - pubmed
The hypophosphatemic mouse model ( Hyp ) is phenotypically and biochemically similar to the human disease . - pubmed
In 2 out of 9 patients with multifocal demyelinating motor neuropathy , MRI showed focal swelling of the nerve at the site of conduction block . - pubmed
[ Enzymatic protein hydrolysates for the nutrition of children suffering from a food allergy ] . - pubmed
From an s.c.-passaged subline of an ascites - converted murine sarcoma ( SEWA - AS12 ) , we were able to separate cells adapted to the ascites form of growth from cells that can only grow in the solid form on the basis of their differential adherence to plastic . - pubmed
Vitreous fluorophotometry in patients with Best ' s macular dystrophy . - pubmed
Ten patients with Best ' s macular dystrophy were examined with vitreous fluorophotometry and results were compared with a normal population . - pubmed
[ Therapeutic tactics in inflammatory diseases of the gallbladder in patients with bronchial asthma ] . - pubmed
The authors describe curative methods of treatment of inflammatory diseases of the gallbladder in 12 patients with bronchial asthma . - pubmed
Sanitation of the surgical infection focus ( cholecystectomy ) improves the clinical course of bronchial asthma , positively influences the immune status of the patients . - pubmed
One hundred and fifty - two patients with idiopathic scoliosis were treated at the Alfred I. duPont Institute with the Milwaukee brace between 1961 and 1972 . - pubmed
This study includes 94 patients and was undertaken to evaluate the effectiveness of Milwaukee brace treatment in managing various sequelae associated with idiopathic scoliosis , such as degree of curvature and trunco - pelvic alignment , and to assess the degree of spinal stability after treatment . - pubmed
The tissue distribution of these radiolabeled compounds in BDF1 mice bearing Lewis lung tumors has been investigated . - pubmed
Zimelidine , a selective inhibitor of serotonin ( 5 - HT ) reuptake in the CNS , was administered to narcoleptic patients . - pubmed
Zimelidine , however , has no anticholinergic effect , so it is unlikely that cholinergic mechanisms thought to be important in animal cataplexy would play a major role in human cataplexy . - pubmed
After exercise , NIDDM subjects had muscle glycogen concentrations comparable with those of lean and obese subjects . - pubmed
Septicaemia caused by Rahnella aquatilis in an immunocompromised patient . - pubmed
The control of Ostertagia ostertagi infections in Australia is aimed specifically at young cattle in their first and second year of grazing after weaning . - pubmed
Cefoperazone plus mezlocillin for empiric therapy of febrile cancer patients . - pubmed
Two dosing regimens of cefoperazone plus mezlocillin were compared in a prospective , randomized trial for therapy of febrile cancer patients . - pubmed
Although the overall response rate was higher with the higher dose regimen ( 78 percent versus 66 percent , p = 0.04 ) , the two regimens were comparable in patients with documented infections ( 72 percent versus 68 percent ) . - pubmed
Hypoprothrombinemia was a side effect , especially with the higher dose regimen , before prophylactic vitamin K was routinely administered to patients . - pubmed
[ The invasiveness of cerebral gliomas in patients of various ages ] . - pubmed
We have described a 25 - year - old man with an idiopathic dilated biventricular cardiomyopathy and end - stage glomerulonephritis due to IgA nephropathy , who was found incidentally at angiographic examination to have an anomalous right coronary artery arising from the main pulmonary artery . - pubmed
The purpose of this report is to present a 5 year experience in electrophysiologically guided surgical treatment of post - infarction ventricular tachycardia ( VT ) in a consecutive series of 39 patients . - pubmed
In conclusion , long - term methandienone treatment results in cardiac hypertrophy in dogs , reduces its response to an inotropic loads and leads to working on larger ventricular volumes . - pubmed
Lung pathology studies revealed neutrophilic alveolitis with intraalveolar and intracapillary neutrophil infiltration in the C5'-treated animals . - pubmed
In the experimental group , bilirubin was infused for 4 h. The cerebral bilirubin content in the bilirubin - infused group was 11.0 + /- 1.4 nmol / g of cerebral cortex ( mean + /- SEM ) , consistent with levels found in infants with kernicterus . - pubmed
Dietary glucarate - mediated reduction of sensitivity of murine strains to chemical carcinogenesis . - pubmed
The level of the enzyme in the murine strains is shown to correlate with the urinary excretion of 17 - ketosteroids , which in turn reflects the endogenous level of androgens . - pubmed
Sensitivity of the A / He strain is significantly reduced by dietary calcium glucarate , which is shown to inhibit DNA binding and the induction of pulmonary adenomas by benzo [ a ] pyrene . - pubmed
Electroencephalograms of anesthetized dogs with hydrocephalus . - pubmed
Ten ( 9.3 % ) of 107 patients with hepatocellular carcinoma had considerably increased serum unsaturated vitamin B12 binding capacity . - pubmed
Glucose intolerance in children with chronic renal failure . - pubmed
Carbohydrate metabolism was studied by the hyperglycemic clamp technique in 14 children with moderate to severe chronic renal failure ( CRF ) ( 8 pubertal and 6 prepubertal ) and was compared with 5 healthy prepubertal children and 7 healthy young adults . - pubmed
Children with CRF were glucose intolerant ( lower M ) , hyperinsulinemic ( higher I ) , and insulin resistant ( lower M / I ) compared with the control children . - pubmed
Pubertal children with CRF had lower M and lower M / I compared with prepubertal children with CRF . - pubmed
M and M / I correlated with glomerular filtration rate ( GFR ) in the 8 pubertal children , while M / I also correlated with GFR in the 6 prepubertal children with CRF . - pubmed
Carcinogenesis studies of L - ascorbic acid were conducted by offering diets containing 0 , 25,000 or 50,000 ppm L - ascorbic acid to groups of 50 F344 / N rats and 50 B6C3F1 mice of each sex for 103 wk . - pubmed
Studies on the inheritance of vaginal septa in mice , a trait with low penetrance . - pubmed
Cerebral angiographic findings of 32 Japanese patients with carotid system TIA 's were compared with those of an equal number of age and sex matched American Caucasians . - pubmed
[ Metabolism of biogenic amines in patients with active pulmonary tuberculosis complicated by nonspecific endobronchitis ] . - pubmed
Thirty - nine patients with severe cardiac failure and a previous transmural myocardial infarct were studied prospectively to assess the ability of M - mode echocardiography to detect resectable left ventricular aneurysms . - pubmed
Subsequent angiography showed an aneurysm in 23 patients and diffuse left ventricular damage in 16 . - pubmed
Nine ( 57 % ) of the patients without aneurysm had either left ventricular end - systolic dimensions in excess of 6 cm combined with reduced contraction of the base of the left ventricle ( fractional shortening of the level of the mitral valve less than 20 % ) , or gross reduction of contraction ( fractional shortening less than 15 % ) regardless of left ventricular dimension . - pubmed
In 21 ( 91 % ) of the patients with a left ventricular aneurysm its presence was correctly predicted either by fractional shortening in excess of 20 % ( 16 patients ) or gross delay of mitral valve opening ( greater than 80 ms 16 patients ) . - pubmed
coli strains , 33 % possessed O6 , O8 , or O78 ; 93 % of these were stable producers of LT , and 86 % produced both Lt and ST . - pubmed
coli strains might be considered as true enteropathogenic bacteria ( enterovirulent E. - pubmed
Electroencephalographic and evoked response correlates of trimethyltin induced neuronal damage in the rat hippocampus . - pubmed
Trimethyltin produces localized neuronal damage in the rat hippocampus , amygdala and pyriform cortex when given systemically . - pubmed
This was a double - blind study designed to compare the efficacy and tolerability of diclofenac / misoprostol and diclofenac in patients with acute tendinitis / bursitis of the shoulder . - pubmed
Abdominal pain , nausea and vomiting occurred somewhat more frequently with diclofenac / misoprostol , but patient withdrawals due to adverse events did not differ markedly between the groups . - pubmed
Integrity and characteristics of secondary oesophageal peristalsis in patients with gastro - oesophageal reflux disease . - pubmed
The aim of the study was to evaluate the integrity and characteristics of secondary peristalsis in patients with gastro - oesophageal reflux disease . - pubmed
Studies were performed in 22 patients with reflux disease and 20 age matched controls . - pubmed
It was found that primary peristalsis was normal in 19 of 20 control subjects and in 14 of 22 patients with reflux disease . - pubmed
In patients with reflux disease , intact secondary peristalsis was triggered infrequently by air and water distension ( median success rate of 0 % for both stimuli ) and occurred significantly less frequently than in control subjects ( 50 % and 30 % respectively ) . - pubmed
Peristaltic velocity for air and balloon induced secondary peristalsis was also similar in control subjects and patients with reflux disease whereas water induced secondary peristalsis was slower in the reflux patients . - pubmed
Oral tolerance therapy has recently been applied to several human autoimmune diseases . - pubmed
One hundred and thirty - three Caucasian patients ( 26 males ) with GD and 85 local controls were included in this study . - pubmed
[ Meningoencephalitis caused by Yersinia enterocolitica ] . - pubmed
AIDS - associated strains of M. - pubmed
Lupus nephritis in children -- a review of 167 patients . - pubmed
BACKGROUND : Relatively few studies have been made of children with lupus nephritis . - pubmed
The prognosis of children with lupus nephritis is ominous for those with diffuse proliferative glomerulonephritis and active interstitial inflammation . - pubmed
OBJECTIVES : To evaluate the clinical course , histopathology , and prognosis of lupus nephritis in children , to identify the risk factors for renal failure and mortality , and to share our experience in treating lupus nephritis in children . - pubmed
METHODS : Retrospectively , 167 children under 18 years of age with lupus nephritis at Veterans General Hospital - Taipei , Taiwan from 1979 to 1991 were studied . - pubmed
All children surviving without renal failure were maintaining their normal lives with little organ dysfunction . - pubmed
Spontaneous GNBM appeared to have a sudden onset , a relatively fulminant course , and was caused most often by Escherichia coli . - pubmed
There were signs that many of the schizophrenic patients , especially the men , used the emergency rooms as a means of human contact and a " shelter " , compensating for the lack of a more personal social network . - pubmed
For many years patients with sepsis and septic shock have been treated with antibiotics , fluids , surgery ( if indicated ) and , in the more severe cases , inotropic and ventilatory support . - pubmed
One hundred eleven patients ( 89 PMR , 14 TA and 8 PMR+TA ) were studied . - pubmed
In 56 patients with PMR a temporal artery biopsy was performed ; in none of these biopsies was active arteritis found . - pubmed
Of the 19 patients with TA or PMR+TA , where a temporal artery biopsy was performed , arteritis was found in 15 patients . - pubmed
Side effect of the medication included vertebral compression in 10 patients , most of whom were using corticosteroids . - pubmed
Malignancies were diagnosed in 12 of the 111 patients . - pubmed
Cytotoxic potencies of the drugs was tested against four representative human tumor cell lines : SKOV3 , SKLVB , HT29 , and KB . - pubmed
Vertebral artery dissection ( VAD ) is an important cause of posterior circulation stroke in young adults . - pubmed
Between 1989 and 1995 we identified 24 patients with a vertebral artery dissection and 1 patient with a basilar artery dissection ( 8 females and 17 males , 23 - 60 years of age , mean 41.2 years ) . - pubmed
Follow - up examinations revealed recanalization in 52 % of initially stenosed or occluded vertebral arteries ; four patients developed a pseudoaneurysm , and two of them underwent ligation of the VAD . - pubmed
METHODS : In the July / August 1995 issue of APIC News , the committee published a survey on the prevalence of infection control " sacred cows , " practices considered to be outdated and ritualistic . - pubmed
We studied the acute ventilatory response to hypoxia ( AHVR ) in 10 patients with chronic heart failure ( CHF ) and in 10 subjects with normal left ventricular function ( NLVF ) before and after 8 weeks of home - based physical training . - pubmed
The AHVR is not substantially altered in patients with CHF compared to subjects with NLVF . - pubmed
However , exercise increases the AHVR in patients with CHF , as it does in normals . - pubmed
These data suggest that the abrupt addition of desflurane may have adverse consequences in patients at risk for intracranial hypertension . - pubmed
We suggest that FDG - PET seems to be useful in differentiating recurrent tumor from radiation necrosis in patients with liposarcoma after therapy . - pubmed
Use of DHEA in a patient with advanced prostate cancer : a case report and review . - pubmed
A patient with advanced prostate cancer with progressive symptomatology was treated with DHEA after other treatment regimens failed . - pubmed
METHODS : The minimum inhibitory concentration ( MIC ) to ampicillin / sulbactam ( A / S ) , amoxycillin / clavulanic acid ( A / C ) , ticarcillin / clavulanic acid ( T / C ) and piperacillin / tazobactam ( P / T ) assessed was in 245 strains of E. - pubmed
Retrospective analysis of results of electromyography and nerve conduction velocity was performed in 169 patients with lower back pain , mostly caused by trauma . - pubmed
Peripheral entrapment of nerves ( tarsal tunnel syndrome and anterior tarsal tunnel syndrome ) were found in 5.3 % of patients , signs of acute or chronic partial muscle denervation of corresponding muscles of lower extremities in 21.8 % of patients , and abnormally prolonged F - wave latency in 12.5 % of patients . - pubmed
We describe a case of a young patient carrying the mutation , with an AMI caused by large bilateral intracoronary thrombi , that underwent direct PTCA . - pubmed
OBJECTIVE : To determine the effects of the nitric oxide ( NO ) precursor L - arginine on the airway NO concentration in patients with preeclampsia . - pubmed
No patient required reoperation for treatment of a fistula . - pubmed
Six patients with uncomplicated falciparum malaria received artesunate for 5 days . - pubmed
A chronic coronary occlusion of & gt ; or = 1 month duration ( range 1 to 33 months ; median 3.3 ) was successfully recanalized in 41 patients . - pubmed
Early reocclusion ( subacute stent thrombosis ) was observed in 1 patient ( 2.4 % ) . - pubmed
Investigations with 52 patients indicated that volumes of & gt ; 100 microliters are rarely required for topical treatment of condylomata . - pubmed
Effects of dexamethasone on meconium aspiration syndrome in newborn piglets . - pubmed
We examined the effects of dexamethasone on lung function in a piglet model of meconium aspiration syndrome . - pubmed
We induced lung injury in 10 newborn piglets ( age 5 + /- 0.2 d ) with 4 mL / kg body weight of 20 % sterile human meconium in normal saline given via tracheostomy . - pubmed
In summary , a two - dose course of 0.5 mg / kg of dexamethasone improved blood gases and lung function in a piglet model of meconium aspiration syndrome . - pubmed
Then a laboratory experiment was conducted in order to construct a computer simulation model ( human model ) that describes human cognitive behaviour on detecting and diagnosing plant anomaly causes . - pubmed
AIMS : Ulcerative colitis is predominantly a disease of nonsmokers and transdermal nicotine has therapeutic value in active disease ; however side - effects are troublesome . - pubmed
Clinically , no reaccumulation of pleural effusion for at least 4 weeks was observed in four patients . - pubmed
In this report , a 25 - year old patient developing pneumothorax while on the treatment for miliary tuberculosis treatment is presented and the related literature has been reviewed . - pubmed
Adult male Sprague - Dawley rats were subjected to 90 min intraluminal middle cerebral artery occlusion and the drug was administered intravenously immediately or 2 h after reperfusion . - pubmed
However , this high level of overexpression is associated with bradycardia and increased incidence of arrhythmia during ischemia in intact mice , which interfered with studies to determine whether this line of TG mice might also be protected against myocardial infarction ( MI ) in vivo . - pubmed
METHODS : The comet assay was used to quantify nuclear DNA damage in neutrophils from SLE patients ( n = 20 ) , control subjects ( n = 15 ) and RA patients ( n = 15 ) . - pubmed
Thus in the age of expensive polypharmacy with some degree of untoward reactions , immunotherapy may be helpful in selected allergic and asthmatic patients . - pubmed
Cross protection by strains of tomato spotted wilt virus and a new theory to explain it . - pubmed
CARDIOVASCULAR MANIFESTATIONS OF THE HURLER SYNDROME : HEMODYNAMIC AND ANGIOCARDIOGRAPHIC OBSERVATIONS IN 15 PATIENTS . - pubmed
Sixty - eight patients admitted with CAP were included . - pubmed
Juxtaglomerular apparatus T - cell infiltration affects glomerular structure in Type 1 diabetic patients . - pubmed
METHODS : We classified 89 Type 1 diabetic patients by immunohistochemical analysis as either juxtaglomerular apparatus T - cell positive ( n=37 ) or T - cell negative ( n=38 ) . - pubmed
Thus , juxtaglomerular apparatus immunologic injury in Type 1 diabetes patients could delay the clinical consequences of diabetic nephropathy . - pubmed
In vivo , XID mice show reduced severity of inflammatory diseases in models of experimental autoimmune encephalomyelitis ( EAE ) , dextran sulfate sodium ( DSS)-induced colitis , and carrageenan - induced acute edema . - pubmed
Also , polymorphonuclear neutrophil granulocytes ( PMNs ) in XID mice show poor ROI and nitric oxide ( NO ) induction , along with a reduction in PMN recruitment to peritoneal inflammation . - pubmed
A prospective randomized study for the treatment of bone loss with vitamin d during kidney transplantation in children and adolescents . - pubmed
Apart from transient hypercalcemia in 1 patient in group 2 , no other significant adverse effects were noted . - pubmed
METHODS : Ninety - five AAA patients undergoing EVR had the endografts implanted percutaneously via 14 - F to 20 - F sheaths in a prospective nonrandomized study . - pubmed
Blood loss , operative time , and length of stay ( LOS ) were compared to 26 AAA patients undergoing EVR with bilateral femoral cutdowns before the percutaneous technique was available . - pubmed
Neuronal tissue transplantation is a potential way to replace degenerated spiral ganglion neurons ( SGNs ) since these cells can not regenerate in adult mammals . - pubmed
CONCLUSION(S ): Although concerns remain concerning distension and potential injury resulting from use of the system , enough data have been gathered to warrant further study of this material for use in humans . - pubmed
We present the case of a patient who presented with recurrent syncope . - pubmed
METHODS : To quantify the concentration of conjugated DX-8951 , DX-8951 and G - DX-8951 in human tissues , six patients with different solid tumor types received 6.0 mg / m(2 ) of DE-310 ( as equivalent of DX-8951 ) as a single three - hour infusion administered 7 days ( + /-2 days ) prior to scheduled tumor resection . - pubmed
Concentrations of conjugated DX-8951 , DX-8951 and G - DX-8951 were in general similar in tumor and relevant normal tissue samples and preferential accumulation of DE-310 , DX-8951 and G - DX-8951 in human tumor tissues was not observed . - pubmed
Cysteamine , the dimer of cystamine , is an orphan drug approved for the treatment of nephropathic cystinosis and has a similar benefit in the murine model but with a narrower therapeutic window . - pubmed
In a single - center open - label study , we determined the maximum tolerable dose ( MTD ) and side effects of cysteamine in people with Huntington ' s disease . - pubmed
We conclude that , at a dose of 20 mg / kg per day , cysteamine was tolerable in people with Huntington ' s disease . - pubmed
RESULTS : The technique was used in the treatment of six patients with recurrent ankylosis of the mandible ranging in age from 9 to 38 years . - pubmed
OBJECTIVES : To determine whether children with prenatally diagnosed mild pyelectasis have more urinary tract morbidity during childhood than children without this finding . - pubmed
METHODS : Case - control study in children with pyelectasis ( anteroposterior diameter of the fetal renal pelvis of 5 - 10 mm ) . - pubmed
We present the case of a 32 - year - old woman suffering who suffered from mild intracranial hypertension , gait disturbance and vertigo for one year . - pubmed
Reconstitution with human cells can be achieved using large numbers of peripheral blood lymphocytes , but levels of engraftment are poor and graft versus host disease ( GVHD ) frequently occurs . - pubmed
In conclusion , we show that intraperitoneal injection of 30 - 40 x10(6 ) human splenocytes into SCID / beige mice induces a quick and functional engraftment of human T , B and NK cells with no risk of GVHD . - pubmed
The chromosome aberration assay in the bone marrow cells of C57BL / 6 mice was used to study the cytogenetic activity of ribavirin ( 10 , 50 , 100 , 200 , and 400 mg / kg , p.o . ) - pubmed
We have reported the isolation of the tetranortriterpenoid 1 - cinnamoyl-3,11 - dihydroxymeliacarpin ( CDM ) from partially purified leaf extracts of Melia azedarach L. ( MA ) that reduced both , vesicular stomatitis virus ( VSV ) and Herpes simplex virus type 1 ( HSV-1 ) multiplication . - pubmed
Twenty children had surgery alone ; eight ( 40 % ) experienced recurrence ; and four died . - pubmed
Eighteen children had surgery and adjuvant chemotherapy ; one experienced recurrence and died . - pubmed
Four of nine children with recurrence survived . - pubmed
CONCLUSION : Adjuvant chemotherapy appears to benefit type I PPB patients . - pubmed
OBJECTIVE : Low bone mineral density has repeatedly been reported in patients with major depressive disorder ( MDD ) , and MDD has been discussed as a risk factor for the development of osteoporosis . - pubmed
MDD in young adults often occurs in the context of borderline personality disorder ( BPD ) , and both MDD and BPD have been associated with a dysregulation of the hypothalamic - pituitary - adrenal system and subsequent hypercortisolemia . - pubmed
To date , it is unclear whether comorbid BPD in depressed patients modulates the extent of bone mass reduction . - pubmed
Patients with BPD alone and healthy women served as comparison groups . - pubmed
METHOD : Twenty - four patients with MDD and 23 patients with comorbid MDD and BPD were included . - pubmed
Sixteen patients with BPD and 20 healthy women of similar body mass index served as the comparison group . - pubmed
For data analysis , the group of depressed patients without comorbid BPD was divided according to age into two groups ( younger depressed patients with a mean age of 30 years and older patients with a mean age of 42.9 years ) . - pubmed
CONCLUSION : Depression is associated with reduced bone mass , in particular in patients with comorbid BPD . - pubmed
We conclude from our data that a history of MDD with and without comorbid BPD should be considered as a risk factor in clinical assessment instruments for the identification of persons prone to osteoporosis . - pubmed
PDT was administered to NR - S1 mouse squamous cell carcinoma or normal mouse skin . - pubmed
The patients have quick functional recovery , as evaluated by the length of postoperative ileus ( 60.0 + /- 12.0 h ) , hospitalization ( 9.0 + /- 1.5 days ) and degree of postoperative pain ( 4.0 + /- 0.5 , visual analogue scale ) . - pubmed
Patients with acute coronary syndrome ( n=148 ) were followed after an initial attack for subsequent ischemic cardiovascular events ( composite end point of death , myocardial infarction , recurrent unstable angina , or stroke ) . - pubmed
The cataract phenotype gave the appearance like a " pearl box " in these two affected individuals of this family . - pubmed
In planning treatment for cancer patients , it is critical to avoid inappropriate treatment decisions based on misdiagnosis of a benign lesion as a metastasis or primary liver malignancy . - pubmed
Both groups were subdivided in patients with hypogonadism and normal gonadal function . - pubmed
Matched pairs of patients with stroke , with and without lateropulsion , were compared for functional outcomes and discharge destination following inpatient rehabilitation . - pubmed
METHODS : A retrospective chart review of patients with ischemic stroke at an inpatient rehabilitation hospital matched 36 pairs of patients with versus without lateropulsion . - pubmed
Lower extremity weakness was greater in the lateropulsion group at discharge ; patients with right brain damage accounted for this difference . - pubmed
Patients with lateropulsion required more dependent living situations at discharge , especially if they had right brain damage . - pubmed
The establishment of temperature - sensitive mutant strains of T. - pubmed
The temperature - sensitive mutant ts-4 strain disappears from tissues of immunocompetent mice without forming tissue cysts and induces protection against challenge with virulent strains of the parasite , and a protocol is provided for infection with this mutant strain . - pubmed
Support protocols present methodology for evaluation of progression of infection and immune response to the parasite , maintenance of T. - pubmed
gondii tissue cysts and tachyzoites , as well as preparation of T. - pubmed
A 72 - year - old man born in Arizona with a heavy smoking history , presented with a 1 - month history of weakness , night sweats , exertional dyspnea , and left pleuritic chest pain . - pubmed
OBJECTIVES : Current indications for therapeutic hypothermia ( TH ) are restricted to comatose patients with cardiac arrest ( CA ) due to ventricular fibrillation ( VF ) and without circulatory shock . - pubmed
Additional studies are needed to evaluate the benefit of this treatment in more heterogeneous groups of patients , including those with non - VF rhythms and/or shock and to identify early predictors of outcome in this setting . - pubmed
INTERVENTIONS : TH to 33 + /- 1 degrees C ( external cooling , 24 hrs ) was administered to patients resuscitated from CA due to VF and non - VF ( including asystole or pulseless electrical activity ) , independently from the presence of shock . - pubmed
Seventy - four patients ( VF 38 , non - VF 36 ) were included ; 46 % had circulatory shock . - pubmed
CONCLUSIONS : Time from collapse to ROSC is strongly associated with outcome following VF and non - VF cardiac arrest treated with therapeutic hypothermia and could therefore be helpful to identify patients who benefit most from active induced cooling . - pubmed
All patients were satisfied with the scar mark . - pubmed
Total RNA of CD3 + T cells isolated from six RRMS patients taken at the peak of acute relapse and at the point of complete remission was processed for DNA microarray analysis . - pubmed
However , nowadays many obese patients are treated with lipid lowering drugs before the start of sibutramine therapy and their effects in these patients have not been investigated . - pubmed
Primary outcomes were time to patient death and graft loss , complications and renal function . - pubmed
Between 1997 and 2007 , 2427 strains of Streptococcus pneumoniae were isolated in part from cerebrospinal fluids , blood and middle ear fluid , from children and adults . - pubmed
After surgery two patients developed an intra - abdominal abscess , drained laparoscopically or percutaneously , and one patient had another site - specific infection . - pubmed
We investigated vancomycin and daptomycin efficacy for Staphylococcus aureus isolates at our institution by testing 221 methicillin - sensitive and 299 methicillin - resistant isolates recovered from serious infections between 1979 and 2007 using a microdilution method . - pubmed
Of the patients with invasive fungal infections , 33.6 % were homozygous extensive metabolizers , 50.0 % heterozygous extensive metabolizers and 16.4 % poor metabolizers . - pubmed
It is presently unknown whether mtDNA abnormalities are present in single human ALS neurons . - pubmed
Carotid blowout is a devastating complication in patients with head and neck malignancy , and is associated with high morbidity and mortality . - pubmed
For patients with bleeding originating in the internal or common carotid artery , treatment options are limited . - pubmed
We describe two cases of pseudoaneurysmal rupture in the common carotid artery with massive bleeding in patients with head and neck malignancies and a history of long - term radiation treatment . - pubmed
Although these endovascular treatments often result in recurrent carotid blowout syndrome , they can be useful and effective in treating emergent carotid rupture in patients for whom balloon occlusion test is contraindicated . - pubmed
BACKGROUND : Epidemiology and imaging studies showed that cognitively normal ( NL ) individuals with a maternal history ( MH ) of late - onset Alzheimer ' s disease ( LOAD ) might be at increased risk for Alzheimer ' s disease ( AD ) compared with NL with a paternal history ( PH ) and NL with a negative family history of LOAD ( NH ) . - pubmed
METHODS : Fifty - nine 40 - 80 - year - old NL subjects were examined , including 23 MH and 14 PH whose parents had a clinician - certified diagnosis of LOAD and 22 NH . - pubmed
A multicenter phase - II study of 5 - FU , leucovorin and oxaliplatin ( FOLFOX6 ) in patients with pretreated metastatic colorectal cancer . - pubmed
OBJECTIVE : Infusional 5 - fluorouracil and leucovorin with oxaliplatin is one of the standard regimens for patients with pretreated metastatic colorectal cancer , as well as for first - line chemotherapy . - pubmed
The objective of this study was to evaluate the efficacy and safety profile of FOLFOX6 in Japanese patients with pretreated colorectal cancer . - pubmed
METHOD : Fifty - one metastatic colorectal cancer patients who failed to respond to first - line chemotherapy were enrolled in the study from April to July 2005 . - pubmed
CONCLUSION : The results of our study suggest that FOLFOX6 had an acceptable profile in terms of both efficacy and safety in previously treated colorectal cancer patients . - pubmed
Patients with trigeminal neuralgia , a rare facial neuropathic pain , present to both medical and dental specialists . - pubmed
[ Diagnosis and therapy of a dog with an atypical eosinophilic cellulitis ] . - pubmed
A 6 years old female bernese mountain dog was seen for a nodular and erythemato - edematous dermatosis resistant to therapy . - pubmed
The histopathological exam showed a eosinophilic cellulitis with flame figures , which are caracteristic for the Wells ' syndrome in human . - pubmed
The children who have had a history of painful crisis 1 - 4 , 5 - 10 , and over 10 times were classified as group 1 , group 2 , and group 3 , respectively . - pubmed
The depression levels of the children in group 3 were higher than group 1 ( P = .018 ) . - pubmed
Typically , patients are diagnosed through exclusion of neurological disease and the absence of pathologic neurophysiological diagnostic findings . - pubmed
Here , we investigate the neural basis of this disorder by combining electrophysiological ( event - related potentials ) and hemodynamic measures ( functional magnet resonance tomography ) in a patient with hysterical blindness before and after successful treatment . - pubmed
DESIGN , SETTING , AND PARTICIPANTS : Forty - four consecutive patients who underwent laparoscopic partial nephrectomy ( LPN ) or robot - assisted partial nephrectomy ( RAPN ) from June 2008 to May 2009 for a single cT1 renal tumour were included in this prospective protocol . - pubmed
A 42 year old man with bilateral exophthalmos and weight loss . - pubmed
METHODS : In vitro the human synovial sarcoma cell line SW982 , the murine fibrosarcoma cell line BFS-1 and primary human fibroblasts as a control were exposed to [ D ]- K3H3L9 , a 15mer D , L - amino acid designer HDP . - pubmed
The local intratumoral administration of [ D ]- K3H3L9 in the athymic and syngeneic mice models significantly inhibited tumor progression . - pubmed
BACKGROUND : Understanding transmission dynamics of the pandemic influenza A ( H1N1 ) virus in various exposure settings and determining whether transmissibility differed from seasonal influenza viruses was a priority for decision making on mitigation strategies at the beginning of the pandemic . - pubmed
CONCLUSIONS : Secondary attack rates for pandemic influenza A ( H1N1 ) were comparable to seasonal influenza estimates suggesting similarities in transmission . - pubmed
METHODS AND RESULTS : OPTIMAL was an observational , prospective study undertaken at 79 medical centres in France in patients with STEMI undergoing pre - hospital thrombolysis ( PHT ) within six hours of symptom onset and coronary angiography within six hours of thrombolysis . - pubmed
PATIENTS / METHODS : Twenty - seven SCAD patients underwent a 5 - year follow - up ( 13 males , 14 females ; mean age , 63.71 years ; range , 50 - 85 years ) . - pubmed
Eleven patients were affected by type A , eight by type B , four by type C and four by type D SCAD . - pubmed
MATERIALS AND METHODS : Left - hand radiographs of 679 children ( 375 boys ) ranging in age from 1 day to 18 years old were obtained for trauma in the period 2001 - 2009 and were evaluated for bone age according to G&P. Individual bone age was plotted against calendar age and smoothed to obtain the association between calendar age and bone age . - pubmed
Evaluation of multiple myeloma patients presenting with renal failure in a university hospital in the year 2010 . - pubmed
BACKGROUND : The aim of this cross - sectional study was to evaluate multiple myeloma patients presenting with renal failure in a University hospital . - pubmed
METHODS : The records of all the patients diagnosed with multiple myeloma in the departments of hematology and nephrology at Gazi University Hospital between January 2010 and January 2011 were reviewed retrospectively . - pubmed
RESULTS : Eight ( 26.7 % ) of the 30 patients had renal failure and 4 ( 50 % ) patients with renal failure required renal replacement therapy with hemodialysis after admission . - pubmed
In one of the eight patients ( 12.5 % ) creatinine levels improved , but did not reach the level defined as reversal of renal failure . - pubmed
The renal functions of the three ( 37.5 % ) patients did not improve and they remained on chronic hemodialysis program during which one of them died due to a cerebrovascular accident and one other patient was lost due to follow - up . - pubmed
We also review studies with mice , which demonstrate that nutritional supplementation can alleviate multiple genetic risk factors for AD . - pubmed
OBJECTIVE : To estimate the prevalence of virus C hepatic infection and to illustrate the various socio - economic , behavioural and medical factors related to infection with Hepatitis C ( HCV ) among apparently healthy individuals . - pubmed
Patients with PKD were aged 58 + - 13 years and included 46 % women 14 % Blacks , respectively . - pubmed
SNP genotyping identifies new signatures of selection in a deep sample of West African Plasmodium falciparum malaria parasites . - pubmed
We used a high - density single - nucleotide polymorphism array to genotype 75 Plasmodium falciparum isolates recently collected from Senegal and The Gambia to search for signals of selection in this malaria endemic region . - pubmed
Bambusa textilis McClure is a traditional Chinese medicinal plant belonging to the Bambusoideae subfamily and used to treat chronic fever and infectious diseases . - pubmed
Improved neurologic prognosis for a patient with propionic acidemia who received early living donor liver transplantation . - pubmed
Despite medical therapy , patients with propionic academia ( PA ) still display a tendency to develop epilepsy . - pubmed
Patients with neonatal - onset PA who have received early living donor liver transplantation ( LDLT ) are limited in number , and the effect on neurologic prognosis , including epilepsy , is not clear . - pubmed
We report a patient with PA whose EEG findings improved dramatically after undergoing LDLT at age 7 months . - pubmed
The survey of diastolic function changes in end - stage renal disease patients before and 3 and 6 months after kidney transplantation . - pubmed
INTRODUCTION : Left ventricular diastolic dysfunction , which is prevalent in end - stage renal disease , predicts morbidity and mortality among affected patients . - pubmed
The aim of this study was to evaluate diastolic function changes in end - stage renal disease patients before as well as 3 and 6 months after kidney transplantation . - pubmed
PURPOSE : This study was carried out to determine the ocular pharmacokinetics , efficacy and potential endothelial toxicity of moxifloxacin ( MF ) after a single intracameral bolus injection of 500 microg/0.1 ml in a rabbit model . - pubmed
RESULTS : Moxifloxacin reaches higher concentration than the MIC of all common endophthalmitis pathogens in the AH and exceeds the mutant prevention concentration levels for Streptococcus pneumonia , Streptococcus viridans , flouroquinolone susceptible Coagulase - negative staphylococcus and flouroquinolone susceptible Staphylococcus aureus for 6 h. The half - life of moxifloxacin in the AH was 2.2 h. Electron and light microscopic evaluation revealed no noticeable sign of toxicity . - pubmed
PURPOSE : Indications that the prenatal action of testosterone in the brain is an important determinant of gender development and improved reconstructive techniques have caused a shift in male gender assignments in patients with 46XY disorders of sex development . - pubmed
MATERIALS AND METHODS : Physical status of 14 men with a mean age of 25 years with disorders of sex development was assessed by structured interview and physical examination . - pubmed
Ejaculatory dysfunction was reported by 7 men . - pubmed
These patients reported decreased sexual desire and activities . - pubmed
Improved survival and quality of life in patients undergoing R1 pancreatic resection compared to patients with locally advanced unresectable pancreatic adenocarcinoma . - pubmed
CONCLUSION : Radical removal ( R0 resection ) is the primary aim of surgery , but also R1 resection seems to improve survival and QoL , compared to outcome in patients with locally advanced tumours not undergoing surgery . - pubmed
Osteomalacia induced by vitamin D deficiency in hemodialysis patients : the crucial role of vitamin D correction . - pubmed
Data in the literature are however scarce about the effects of this deficiency on bone metabolism in hemodialysis ( HD ) patients . - pubmed
Moreover , it is still debated whether low vitamin D levels should be normalized in HD patients . - pubmed
In this paper , we report two cases showing the deleterious consequences of vitamin D deficiency in HD patients which is characterised by hypophosphatemia , hypocalcemia and osteomalacia ( OM ) leading to bone fractures . - pubmed
Adrenal metastases are usually solitary , asymptomatic and diagnosed incidentally during staging of patients with lung cancer . - pubmed
Bilateral adrenal metastases at the time of diagnosis are seen in 3 % of lung cancer patients . - pubmed
Herein we describe a 46 - year old male patient with SCLC who was symptomatic from large bilateral adrenal metastases at presentation . - pubmed
The patient was successfully treated with conventional platinum based chemotherapy and had no complications related to the large adrenal masses ( intratumoral hemorrhage or adrenal insufficiency ) either at presentation or subsequently during treatment and follow up . - pubmed
enterica serovar 4,[5],12 : i:- is considered to be a monophasic variant of Salmonella Typhimurium and is increasingly associated with human infections . - pubmed
A panel of 206 Salmonella strains was used to validate our multiplex real - time PCR against the conventional multiplex PCR recommended by EFSA , i.e. - pubmed
43 Salmonella strains of serovars other than Typhimurium and 163 routine isolates determined by slide agglutination serotyping to have an incomplete antigenic formula compatible with the S . - pubmed
Left atrial volume best predicts recurrence after catheter ablation in patients with persistent and longstanding persistent atrial fibrillation . - pubmed
INTRODUCTION : Patients with persistent and longstanding persistent atrial fibrillation ( AF ) have a higher recurrence rate after antral pulmonary vein isolation ( PVI ) . - pubmed
We sought to determine the clinical , invasive , and noninvasive diastolic function parameters that are associated with AF recurrence after ablation in patients with persistent and longstanding persistent nonvalvular AF . - pubmed
METHODS AND RESULTS : We studied 125 consecutive patients with persistent and longstanding persistent AF who underwent antral PVI at our institution between April 2009 and April 2011 . - pubmed
Ablation eliminated AF in 83 of 125 ( 66.4 % ) patients ( mean age 61.3 + - 8.9 , 81 % male ) during 17.8 + - 7.7 months of follow - up . - pubmed
CONCLUSION : Indexed minimal LA volume is highly associated with ablation success in patients with persistent and longstanding persistent AF . - pubmed
METHODS : A total of 265 patients aged 45 years or older admitted with low - energy or high - energy fractures were reviewed between January 2010 and May 2011 . - pubmed
RESULTS : Of the 265 patients ( 175 female , 90 male ) , 259 ( 97.7 % ) patients had low - energy fractures and 6 ( 2.3 % ) suffered high - energy fractures . - pubmed
Bone mineral density testing was significantly higher in low - energy fracture patients who were treated by a young orthopedist , a common fracture site ( proximal - femur , distal - radius , vertebrae ) or were female ( p<0.05 ) . - pubmed
In the Old World , CL is usually caused by Leishmania major , Leishmania tropica , and Leishmania aethiopica complex which 90 % of cases occurring in Afghanistan , Algeria , Iran , Iraq , Saudi Arabia , Syria , Brazil , and Peru . - pubmed
Recently , some reports showed that some strains of L. - pubmed
Evidence from the metastatic setting suggests that replacing conventional doxorubicin with nonpegylated liposomal doxorubicin ( NPLD ) for early breast cancer may maintain efficacy whilst reducing long - term cardiotoxicity , an important consideration with many patients going on to receive multiple lines of treatment . - pubmed
Consecutive patients with early breast cancer treated with NPLD were assessed for disease progression and changes in cardiac function according to left ventricular ejection fraction ( LVEF ) . - pubmed
NPLD appeared to be a well - tolerated substitute for conventional doxorubicin in patients with early breast cancer . - pubmed
Two thirds of the participating PCPs stated that they routinely provided brief inventions to assist patients in reducing both their tobacco ( 72 % ) and alcohol ( 61 % ) consumption , to encourage them to increase their levels of physical activity ( 72 % ) , and to assist them in adjusting to a more healthy diet ( 66 % ) , and in achieving a healthy body weight ( 69 % ) . - pubmed
Comparison of restrictive and liberal transfusion strategy on postoperative delirium in aged patients following total hip replacement : a preliminary study . - pubmed
Few studies have examined the association between perioperative blood transfusion and postoperative delirium ( POD ) in aged patients undergoing total hip replacement surgery . - pubmed
Twelve patients were found with dysplasia and 13 patients with IGC , all of them occurred in gallbladders removed for gallstone diseases . - pubmed
Median age for cancer patients was 70 years ( range 51 to 85 ) and 54 years for dysplasia ( range 18 to 75 ) . - pubmed
OBJECTIVE : The purpose of this study was to evaluate for the first time the association between 1 - year ablation efficacy and termination mode after repeated catheter ablations in patients presenting with persistent or long - standing persistent AF . - pubmed
METHODS : This prospective study involved 400 consecutive patients ( age 62.7 + - 7.2 years ) who underwent catheter ablation for drug - refractory persistent AF ( 4.6 + - 2.4 months ) using a stepwise ablation approach . - pubmed
RESULTS : AF was terminated by radiofrequency application directly into SR in 135 patients ; passing through AT into SR in 195 patients ; and through DC cardioversion in 70 patients . - pubmed
Research on the efficiency of assistive techniques in phoniatric rehabilitation of patients with unilateral vocal cord paresis yields conflicting results . - pubmed
METHODS : Twenty - four patients ( 17 boys ) who had undergone cranial vault remodeling due to scaphocephaly were compared from 3D - CT imaging datasets . - pubmed
Prevalence of renal insufficiency in hospitalised patients with venous thromboembolic events : a retrospective analysis based on 6,725 VTE patients . - pubmed
Renal function could be determined for 5,710 VTE patients . - pubmed
Of these 21.4 % had an eGFR>90 mL / min , 38.1 % had an eGFR of 60 - 89 mL / min , 17.3 % had an eGFR of 45 - 59 mL / min , 12.5 % had an eGFR of 30 - 44 mL / min , 7.2 % had an eGFR of 15 - 29 mL / min and 3.6 % of the VTE patients had end - stage renal disease . - pubmed
Persistent severe RI was observed in 74.8 % of patients with an eGFR & lt;30 mL / min . - pubmed
Overall , 40.6 % of the VTE patients investigated had an eGFR & lt;60 mL / min ; 10.8 % had an eGFR & lt;30 mL / min . - pubmed
Recently , tumor - induced changes to the human EC surface were described that provided a basis for designing efficient EC - based vaccines capable of eliciting immune responses that targeted the tumor endothelium directly . - pubmed
Of these , there were radiographic findings suggestive of a fungal infection in 38 patients ( 83 % ) . - pubmed
Significant postoperative morbidity attributed to biopsy occurred in 3 of 31 patients ( 10 % ) ; 2 patients had pneumothorax requiring chest tube and intubation and a patient had prolonged intubation . - pubmed
Optogenetic activation of contralateral PL excitatory neurons exerts analgesic and anxiolytic effects in mice subjected to chronic pain , whereas inhibition is anxiogenic in naive mice . - pubmed
Does Staphylococcus aureus have a role in the development of Type 2 diabetes mellitus ? - pubmed
To improve vaccine strain selection , human serologic testing on vaccination - induced cross - reactivity need be emphasized along with virus antigenic characterization by ferret model . - pubmed
METHODS : Patients aged 65 years and older in the American College of Surgeons National Surgical Quality Improvement Program database who underwent ORIF for FN fractures or DF fractures from 2005 to 2012 were identified . - pubmed
CONCLUSION : Postoperative morbidity and mortality of geriatric patients who sustain DF and FN fractures treated operatively were comparable . - pubmed
Methotrexate reduces HbA1c concentration but does not produce chronic accumulation of ZMP in patients with rheumatoid or psoriatic arthritis . - pubmed
OBJECTIVES : The mechanism by which methotrexate ( MTX ) improves glucose homeostasis in patients with rheumatoid ( RA ) and psoriatic arthritis ( PsA ) remains undetermined . - pubmed
METHOD : MTX - naive , non - diabetic RA ( n = 16 ) and PsA ( n = 10 ) patients received uninterrupted MTX treatment for 6 months . - pubmed
CONCLUSION : VR represents a motivational and effective alternative to traditional motor rehabilitation for MS patients . - pubmed
The results showed that VR programs could be an effective method of patients with MS rehabilitation in multiple cognitive and / or motor deficits . - pubmed
CONCLUSION : Whilst Dara can interfere with the IFE to determine clinical responses the FLC assay can be useful in patients who have abnormal FLC ratios prior to Dara therapy to determine responses especially in IgG - kappa Myeloma . - pubmed
Pairwise comparisons of the nucleotide sequences and the deduced amino acid sequences revealed that the four Xinjiang EV - B106 strains had only 80.5 - 80.8 % nucleotide identity and 95.4 - 97.3 % amino acid identity with the Yunnan EV - B106 strain , indicating high mutagenicity . - pubmed
These four strains may share a donor sequence with the EV - B85 strain , which circulated in Xinjiang in 2011 , indicating extensive genetic exchanges between these strains . - pubmed
All Xinjiang EV - B106 strains were temperature - sensitive . - pubmed
[ Interrelation of Electrophysiological and Perfusion Changes in Patients With Left Ventricular Aneurysm ] . - pubmed
The study was aimed at identification of relations between perfusion and electrophysiological changes in left ventricular ( LV ) myocardium in patients with ischemic heart disease ( IHD ) with postinfarction LV aneurysm and ventricular tachycardia . - pubmed
Peri - interventional neurological complication rates in patients undergoing carotid artery stenting depend on the side of the stenosis treated . - pubmed
We investigated if the side of the stenosis treated has an influence on the neurological outcome of our patients . - pubmed
Data of both patient groups were analyzed with respect to the total rate of peri - interventional ischemic cerebral events , defined as transient ischemic attacks , minor and major strokes , respectively . - pubmed
BACKGROUND : Infections greatly influence the outcome of acute myeloid leukemia ( AML ) patients receiving intensive treatment . - pubmed
Effect of Antidepressant Switching vs Augmentation on Remission Among Patients With Major Depressive Disorder Unresponsive to Antidepressant Treatment : The VAST - D Randomized Clinical Trial . - pubmed
Importance : Less than one - third of patients with major depressive disorder ( MDD ) achieve remission with their first antidepressant . - pubmed
Design , Setting , and Participants : From December 2012 to May 2015 , 1522 patients at 35 US Veterans Health Administration medical centers who were diagnosed with nonpsychotic MDD , unresponsive to at least 1 antidepressant course meeting minimal standards for treatment dose and duration , participated in the study . - pubmed
Abnormal results were only found in 6/51 ( 12 % ) patients with MRI and 12/51 ( 24 % ) patients with HRUS . - pubmed
CONCLUSIONS : Brachial plexus sonography could complement MRI in the diagnostic work - up of patients with suspected CIDP and MMN . - pubmed
METHODS : Prospective cohort of 171 participants ( mean age 61 years ; BMI 32 kg / m2 , 71 % female ; 57 % white ) with symptomatic knee OA from a randomized trial comparing 12 - week Tai Chi and Physical Therapy . - pubmed
Materials and methods : The aim of this study was to describe the diagnostic and treating modalities applied in nine patients with CD and EVFs , the clinical / epidemiological features of this clinical entity and to perform a systemic review of the literature , concerning the diagnosis and treatment of this complication . - pubmed
Mean patient reported KOOS activities of daily living and pain scores were each 90 . - pubmed
The aim of this retrospective study was to investigate the prognostic significance of pre - treatment immunological and nutritional statuses in patients with locally advanced gastric cancer ( GC ) , and to use the risk factors to develop a predictive score . - pubmed
Background : The objective of this study was to compare the clinical and radiological outcomes between patients with or without axial symptoms ( AS ) and investigate the risk factors associated with AS by multivariate regression analysis in anterior cervical discectomy and fusion ( ACDF ) . - pubmed
Results : The patients were divided into two groups : one with AS ( AS group , n=35 ) and the other without ( NAS group , n=82 ) . - pubmed
Conclusion : AS do not correlate with recovery of neural function in patients treated by ACDF . - pubmed
The ability of resynchronization to improve LVEF without GDMT suggests that CRT without waiting 3 months for GDMT optimization may benefit some patients with NICM and LBBB . - pubmed
This method provides a novel approach for human intestinal regeneration and can be used to identify potential cancer driver genes . - pubmed
Aims : We sought to examine whether disturbances in central and peripheral circadian rhythms were related to the experience of fatigue in patients with chronic liver disease ( CLD ) . - pubmed
Methods : Fatigued and non - fatigued patients with compensated CLD were enrolled in a prospective pilot study . - pubmed
Results : Six fatigued and six non - fatigued patients were studied ; five participants had cirrhosis . - pubmed
Fatigued patients showed a blunted and delayed cortisol rhythm and fatigue was strongly correlated with cortisol amplitude ( rho=-0.77 , p=0.004 ) and phase ( r=-0.66 , p=0.02 ) . - pubmed
Conclusion : Subtle aberrations in melatonin and adrenal circadian rhythms , as well as reduced sleep efficiency , likely contribute to fatigue in patients with CLD . - pubmed
These abnormalities may ultimately be a therapeutic target to improve quality of life for fatigued patients with CLD . - pubmed
This case of endograft explantation is of even greater complexity , given the patient 's specific history of aneurysm repair in the concomitant setting of a functioning renal allograft . - pubmed
Advanced imaging modalities provide essential anatomic and spatial information in patients with complex heart disease . - pubmed
Many groups have reported the use of 3D printing for preprocedural planning in patients with different causes of heart failure . - pubmed
High expression of both proteins identified a poor prognosis subgroup in patients with locally advanced HNSCC after RCTx . - pubmed
MATERIALS AND METHODS : This was a retrospective study of patients with suspected SpA referred from the rheumatology department of a university teaching hospital undergoing MRI both of the whole spine and of the sacroiliac joints over a 3 - year period . - pubmed
RESULTS : Three hundred and sixty - five patients with suspected SpA undergoing both whole spine and sacroiliac joint MRI were identified . - pubmed
METHODS : A total of 108 patients who presented with parotid duct stenoses ( 130 parotid glands ) were examined with high - resolution US between 2014 and 2017 . - pubmed
Materials and Methods : Fifty - one children with ASD ( five females and 46 males ) aged 7 - 12 participated in the study . - pubmed
Strains of S. - pubmed
Therefore , to explore the mechanism of DEHP - induced splenic toxicity , male quail were employed with 0 , 250 , 500 and 750 mg / kg body weight DEHP by daily gastric perfusion for 45 days . - pubmed
CASE REPORT We present the case of a 48 - year - old male with a personal history of mediastinal Hodgkin lymphoma who was treated with local radiotherapy 20 years ago , and who was admitted to hospital due to dyspnea and oppressive chest pain with efforts . - pubmed
This fact is very relevant , and this report can help determine the aspects of radiotherapy - induced heart disease affecting the mortality and morbidity of these patients . - pubmed
We recruited 48 patients carrying a known or suspected liver disease to undergo gadoxetic acid - enhanced MR imaging . - pubmed
CASE PRESENTATION : A 3 - month - old female patient with the correctable type of biliary atresia underwent a cystoduodenostomy . - pubmed
CONCLUSIONS : Cholangiocarcinoma is extremely rare in patients with biliary atresia . - pubmed
However , physicians should follow up patients with biliary atresia as closely as possible , as malignant tumors secondary to biliary atresia may increase in number in the near future because of the growing number of long - term survivors with biliary atresia . - pubmed
Vaccine - enhanced disease ( VED ) occurs as a result of vaccination followed by infection with virulent Mycoplasma pneumoniae . - pubmed
To date VED has prevented development of an efficacious vaccine against this significant human respiratory pathogen . - pubmed
Preliminary detection of lung hypoperfusion in discharged Covid-19 patients during recovery . - pubmed
Patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension are at risk of developing sleep - related breathing disorders . - pubmed
There should be a strong suspicion of sleep - related breathing disorders in such a patient population , however the precise indications for sleep studies and the type of recording remain to be specified . - pubmed
The diagnosis of obstructive sleep apnoea syndrome in patients with pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension should encourage treatment with continuous positive airway pressure . - pubmed
However , it is prudent not to treat central apnoea and Cheynes - Stokes respiration with adaptive servo - ventilation in patients with chronic right heart failure because of a potential risk of serious adverse effects from such treatment . - pubmed
In this review we will consider the current knowledge of the consequences of sleep - related breathing disorders on pulmonary haemodynamics in patients with and without chronic respiratory disease ( group 3 of the clinical classification of pulmonary hypertension ) and the effect of treatments of respiratory events during sleep on pulmonary hypertension . - pubmed
Does dietary nitrate supplementation with beetroot juice attenuate thermoregulatory and cardiovascular strain in older adults during severe heat stress ? - pubmed
These data suggest nitrate supplementation with beetroot juice does not mitigate thermoregulatory or cardiovascular strain in heat - stressed older individuals . - pubmed
ABSTRACT : This study tested the hypothesis that dietary nitrate supplementation with concentrated beetroot juice attenuates thermoregulatory and cardiovascular strain in older individuals during environmental heat stress . - pubmed
Overall , these findings suggest that dietary nitrate supplementation with concentrated beetroot juice does not attenuate thermoregulatory or cardiovascular strain in older individuals exposed to severe ambient heat stress . - pubmed
MATERIALS AND METHODS : In this prospective study , a group of 567 patients with OSF were enrolled from 1986 to 2017 and followed - up until 2019 . - pubmed
We analyzed the betel quid chewing habits and found all 32 patients with OSCC - chewed betel quid . - pubmed
The OSCC was located in the left or right buccal regions in 23 patients ( 23/32 ; 72 % ) and in the left or right lingual regions in 4 patients ( 4/32 ; 12 % ) . - pubmed
Well , moderately and poorly differentiated squamous cell carcinoma was present in 23 patients ( 23/32 ; 72 % ) , 4 patients ( 3/32 ; 9 % ) , and 5 patients ( 5/32 ; 16 % ) , respectively . - pubmed
CLINICAL RELEVANCE : The long duration of the transformation from the OSF to OSCC suggests more frequent examinations and corresponding treatments are necessary for OSF patients . - pubmed
Introduction and switching of biologic agents are associated with antidepressant and anxiolytic medication use : data on 42 815 real - world patients with inflammatory rheumatic disease . - pubmed
In conclusion , m6A RNA methylation regulators are closely correlated with CESC clinical characteristics andtheselected 6 m6A RNA methylation regulators may be useful for CESC patients personalized treatment . - pubmed
Objectives : Blood bank centers routinely screen for hepatitis B virus ( HBV ) , hepatitis C virus ( HCV ) , and human immunodeficiency virus ( HIV ) to ensure the safety of blood supply and thus prevent the dissemination of these viruses via blood transfusion . - pubmed
Bone diseases such as osteomalacia , osteoporosis , and osteomyelitis are major illnesses that threaten the health of human . - pubmed
BACKGROUND : Lumbar X - rays are usually preferred in patients with lower back pain , but lumbar spinal stenosis ( LSS ) can not be directly observed on lumbar X - ray films . - pubmed
A group of 25 patients with non - Hodgkin ' s lymphoma was investigated . - pubmed
The presence of growth lines in the distal radius was evaluated prior to treatment in 23 psychosocial dwarfs and 25 patients with idiopathic hypopituitarism . - pubmed
Short - term and serial memory in autistic , retarded , and normal children . - pubmed
No differences were found among groups in rate of learning , although the autistic children improved significantly on the second and longer series . - pubmed
The results are interpreted as supporting the view that when MA and response acquisition level are equated with normal and retarded children in a memory task , autistic children do not show any specific memory deficits . - pubmed
Enzootic with ectromelia symptomatology in Sprague - Dowley rats . - pubmed
[ Immunoenzymatic diagnosis ( ELISA ) of human African trypanosomiasis . - pubmed
A comparative study , by ELISA , of purified exoantigen and of five crude antigenic extracts from several strains of T.b . - pubmed
After 13 doses of Ep ( 5 u / dose ) , started either 5 or 21 d after removal of five - sixths of the renal mass , the increase in the red cell volume of uraemic rats was as great as that of non - uraemic ones . - pubmed
The individual developing unilateral adrenocortical carcinoma showed rapid adrenal expansion , feminization , and an abnormal urinary steroid profile after 4 yr of observation for bilateral minor adrenal enlargements . - pubmed
RESULTS : MAI occurred in 8 % of those patients with 1 - day therapy and 10 % with 5 - day therapy . - pubmed
Arthroscopic surgery for osteochondritis dissecans of the femoropatellar joint of the horse . - pubmed
Arthroscopic surgery for the treatment of osteochondritis dissecans was undertaken on 252 femoropatellar joints in 161 horses ( 82 Thoroughbreds , 39 Quarter Horses , 16 Arabians , 9 Warmbloods and 15 others of various breeds ) . - pubmed
Horses with Grade I lesions ( & lt ; 2 cm in length ) had a significantly higher success rate ( 78 % ) than did horses with Grade 2 ( 2 - 4 cm ) or Grade 3 ( & gt ; 4 cm ) lesions ( 63 % and 54 % success rates respectively ) . - pubmed
Intensive strain of racing - horses during training and race is not an end in itself but should be understood from the social task to create exceptionally efficient horses . - pubmed
[ The effect of hemodialysis on neutrophil enzyme activity in patients with uremia ] . - pubmed
Basing on measurements of the activities of 7 lysosomal enzymes , the authors have assessed the enzymic activities of neutrophils in 22 patients with protracted renal insufficiency treated by hemodialysis . - pubmed
[ Doppler echocardiography in the evaluation of hemodynamics in children with bilateral forms of chronic nonspecific inflammatory lung diseases ] . - pubmed
In this work 26 patients with schistosomal specific nephropathy were randomly distributed among three groups . - pubmed
Patients who had another etiologic cause which may explain their kidney disease were not admitted to this study . - pubmed
We conclude that in patients with schistosomal nephropathy , none of the tried therapeutic regimens produce regression of the disease if given to patients with established disease . - pubmed
One hundred and sixteen patients with cervical intraepithelial neoplasia were treated by CO2 laser excisional conization , from 1985 to 1987 . - pubmed
3 ) In our series , 10.3 % ( 6 out of 58 ) of the women with dysplasia or CIS ( surgical margin negative ) required two treatments respectively to eradicate their disease from 9 months to 16 months after laser conization . - pubmed
4 ) None of 72 women developed postoperative cervical stenosis and cervical infection . - pubmed
A total of 24 pregnant women with growth - retarded fetuses were studied to examine the distribution of fetal heart rate accelerations between 30 and 40 weeks ' gestation , as compared with those of fetuses of normal growth that were matched for gestational age and length of fetal heart rate tracings . - pubmed
Proctoscopically diagnosed third - degree haemorrhoids were treated with rubber band ligation ( RBL ) in 92 patients , who were randomly assigned to management with or without twice - daily intake of unprocessed bran for 18 months . - pubmed
A high - fiber diet thus increased the long - term cure rate among patients with third - degree haemorrhoids initially cured by RBL . - pubmed
[ Epidemiologic study of spontaneous mesothelioma in dogs : its possible usefulness in reference to human pathology ] . - pubmed
Two of these patients developed their hydrocephalus after intraventricular hemorrhage , and in six patients the hydrocephalus was associated with myelodysplasia . - pubmed
This is followed by a description of the exocrine pancreatic function in type I diabetes of humans and in experimental insulin deficiency diabetes of rats . - pubmed
Of the 52 patients who died during the follow - up period , hepatocellular carcinoma was the cause of death in 3 ( 33 % ) of the 9 men , and 2 ( 5 % ) of the 43 women . - pubmed
In 2 series of 10 patients , each unilateral laser iridotomy was performed with a YAG - laser prior to cataract surgery . - pubmed
In catheterized rats recovery of liver and body weight lagged behind that of non - catheterized rats . - pubmed
Flavobacterium and Alcaligenes have been implicated in shell egg rots , Staphylococcus aureus has been implicated in food poisoning , and organisms resembling micrococci and actinomycetes have been found in broken - out egg products . - pubmed
We conclude that when third - trimester normoglycemia is maintained in pregnant diabetic patients , one obviates the need for the costly and odious task of daily urine estriol measurements . - pubmed
[ Functional morphology of the myocardium and carotid paraganglion of dogs during electrical stimulation of the carotid sinus nerve in experimental stenocardia ] . - pubmed
6 patients with thrombocytopenia and anaemia had fatty marrow replacement at the site of an iliac crest . - pubmed
The pelvic and sternal marrow cellularity in patients with pancytopenia may not be representative of the cellularity of the whole marrow , and the pelvic marrow especially may be prone to aplasia . - pubmed
The infection rate in chickens increased from 23 % in those weighing less than 500 g , to 73 % in those between 500 and 1,000 g , indicating a rapid rate of acquiring infectin , probably from the soil in which they constantly search for food . - pubmed
Most strains of Toxoplasma isolated from Costa Rican cats produced chronic latent infections in mice . - pubmed
However , even when infected with virulent strains , mice died at a time when numerous bradyzoites had been formed . - pubmed
The value of the Hertel measurement evaluated by a group of patients with thyroid diseases and a control group ] . - pubmed
Exophthalmometry values from routine referrals to a hospital eye clinic are analysed , including adult patients with and without thyroid disease . - pubmed
Thyroid patients with eye muscle involvement ( diplopia , n = 47 ) had significantly higher values ( median 22 mm , range 15 - 31 mm ) but did not differ significantly from a subgroup of 51 patients without thyroid disease , but with " big eyes " as a ( presumably ) physiological finding ( median value 20 mm , range 16 - 25 mm ) . - pubmed
Seven of the patients with left sided tumors had an average 1314 sq mm heart irradiated in the central axis . - pubmed
Because of the reduction in invasiveness that arthroscopy provides , outpatient surgery is now routinely employed for ACL patients . - pubmed
The time to total relief of diarrhea and of all symptoms was also significantly shorter in fleroxacin - treated patients . - pubmed
Harmaline - induced impairment of Pavlovian conditioning in the rabbit . - pubmed
Body weight , crown - rump length , and limb length measurements , synchronized to pubertal onset , suggest that a pubertal growth spurt occurs in male baboons . - pubmed
METHODS : Between 1964 and 1994 40 patients , ranging from 14 months to 52 years old , underwent an operative approach designed to minimize trauma to the sinus node and its blood supply . - pubmed
The anomalous pulmonary veins were redirected across a sinus venosus atrial septal defect ( 33 patients ) or a surgically created atrial septal defect ( 7 patients ) into the left atrium . - pubmed
The atrial septal defect rim was coapted to the intracardiac SVC orifice in 23 patients . - pubmed
RESULTS : One 31 - year - old woman died of severe pulmonary hypertension . - pubmed
All patients remained well over follow - up ( 6 months to 30 years ) , without residual intracardiac defects . - pubmed
Sick sinus syndrome developed late in only 1 patient ( 2.5 % ) . - pubmed
Membrane attack complex in thickened cutaneous sensory nerves of leprosy patients . - pubmed
Therefore , an attempt was made to demonstrate MAC in peripheral nerve biopsies , collected from leprosy patients . - pubmed
Interestingly , we could demonstrate deposition of MAC in involved cutaneous sensory nerves from most of the lepromatous leprosy patients . - pubmed
Recurrent cancer has developed in 4 of the 18 patients ( 22 % ) . - pubmed
The site of first recurrence was the lung in three patients ( 17 % ) and the pelvis in one ( 6 % ) ; no patients recurred in the liver . - pubmed
Seventy dementia patients in hospital and two control groups comprising 50 dementia sufferers in the community and 50 mentally fit elderly people , were investigated to determine which social factors such as life events were associated with the presence of anxiety symptoms . - pubmed
We report a prospective study of thirty four therapeutic temporomandibular arthroscopies that were done during a 24 months period for patients with debilitating joint disorders ( mainly disc displacements with or without reduction ) who had not responded to no - invasive treatment . - pubmed
Previous results have documented a burst of IL-4 mRNA that peaks in draining lymph nodes of susceptible BALB / c mice 16 h after infection with Leishmania major . - pubmed
The severity of congestive heart failure in 31 patients with congenital heart disease was graded by a scoring system which included a description of historical and clinical variables . - pubmed
Patients were divided into a group with no or mild heart failure ( score & lt ; or = 6 ) and a group with severe heart failure ( score & gt ; 6 ) . - pubmed
Efficacy of orchidopexy on spermatogenesis in the immature mutant ' trans - scrotal ' rat as a cryptorchid model by quantitative cytological analysis . - pubmed
OBJECTIVES : To determine whether cryptorchidism is a congenital malformation and whether the impaired spermatogenesis in immature testes can be reversed by early orchidopexy , using the mutant trans - scrotal ( T - S ) rat which is normally masculinized but has cryptorchidism in 85 % of males . - pubmed
1 , with normally descending testes ( normal control , 10 rats ) ; 2 , with undescended testes ( UDT ) treated by orchidopexy ( treated UDT , eight rats ) ; 3 , with UDT treated by a sham operation ( sham - operated UDT , six rats ) ; and 4 , with UDT left untreated ( untreated UDT , six rats ) . - pubmed
CONCLUSIONS : These results show that in the T - S rat with cryptorchidism , the testicular damage is not a congenital malformation and can be reversed with early surgical correction . - pubmed
Fractures of the neck or the pertrochanteric region are often treated with dynamic hip screw especially in elderly patients . - pubmed
We give a case report covering treatment and follow - up for a bilateral spontaneous pertrochanteric fracture in a 45 - year - old man as a result of hepatogenetic osteopathy . - pubmed
Efficacy of pentoxifylline with aspirin in the treatment of frostbite in rats . - pubmed
The efficacy of pentoxifylline -- a haemorrheologic agent along with aspirin -- an analgesic agent was evaluated in the amelioration of the tissue damage due to experimentally induced frostbite in 5 groups ( 20 each ) of rats with body weights ranging between 175 and 200 g. Frostbite was produced experimentally in the hind limbs by exposing the animals to -15 + /- 1 degrees C for 1 h using the harness technique , with simultaneous recording of rectal and environmental temperatures . - pubmed
The combined pharmacological properties of these two drugs might have altered the haemorrheologic status of blood and produced the curative beneficial effect in improving tissue survival following experimentally induced frostbite in rats . - pubmed
PATIENTS AND METHODS : One hundred and seven chronic urticaria patients were studied . - pubmed
Concomitant diseases suggesting autoimmune reactivity were detected in nine patients and , in 16 patients , infections including maxillary sinusitis , streptococcal tonsillitis , and tooth infection were found . - pubmed
INTRODUCTION : There have been only a few studies on differentiated childhood thyroid cancer ( DTC ) in children and adolescents . - pubmed
METHODS : We analyzed the characteristics of DTC with respect to age , gender and histology in 114 patients under 18 years of age . - pubmed
Characteristics of 80 females and 34 males were evaluated , and the prognostic effect of age , gender , histology , multicentric growth , tumor stage and N - status on distant metastases was tested using multivariate discriminant analysis . - pubmed
RESULTS : The incidence of DTC in females was higher than in males with a peak of female : male ratio at puberty , which was more pronounced in children with papillary thyroid cancer , but not with follicular thyroid cancer . - pubmed
Determinants of bone mass in systemic lupus erythematosus : a cross sectional study on premenopausal women . - pubmed
Osteoporosis was defined as a t score below 2.5 SD compared to a reference population of healthy women in at least one region of measurement . - pubmed
Osteoporosis was detected in 22.6 % of patients . - pubmed
Compared with non - osteoporotic patients with SLE , women with osteoporosis had similar age , lower body mass index , significantly longer disease duration ( p & lt ; 0.0001 ) , higher cumulative steroid intake ( p & lt ; 0.006 ) , and higher SLICC / ACR score ( p & lt ; 0.01 ) . - pubmed
CONCLUSION : Osteoporosis is a frequent feature in young patients with SLE . - pubmed
These parameters were also measured in healthy donors and in cancer patients at the time of the diagnosis and following the administration of high doses of cytotoxic drugs requiring stem cell support . - pubmed
OBJECTIVE : To determine the endometrial effects of raloxifene 60 mg / day in postmenopausal women as assessed by vaginal bleeding and endometrial thickness . - pubmed
RESULTS : Raloxifene 60 mg / day was not significantly different from placebo with regard to the incidence of vaginal bleeding , the baseline - to - endpoint change in endometrial thickness , or the proportion of women experiencing an increase in endometrial thickness above baseline after either 12 or 24 months of therapy . - pubmed
CONCLUSION : Raloxifene 60 mg / day for up to 30 months is not associated with vaginal bleeding or increased endometrial thickness in postmenopausal women . - pubmed
Targeted disruption of murine Cryptic results in L - R laterality defects including randomization of abdominal situs , hyposplenia , and pulmonary right isomerism , as well as randomized embryo turning and cardiac looping . - pubmed
Our sample was comprised of 51 patients with late - life MDD and 30 non - depressed controls . - pubmed
Patients with MDD had significantly smaller frontal lobe volumes , together with larger whole brain lesion volumes when compared with controls ( p & lt ; .05 ) . - pubmed
BACKGROUND AND OBJECTIVE : Noninvasive diagnosis of intestinal necrosis is important in planning surgery in preterm infants with necrotizing enterocolitis ( NEC ) . - pubmed
STUDY PARTICIPANTS AND METHODS : Abdominal MRI scans were performed in a group of preterm infants with suspected NEC and compared with surgical findings and to MRI results in a group of control infants . - pubmed
In addition , MRI was performed in 2 preterm infants with suspected NEC who did not require surgery . - pubmed
RESULTS : Six infants with a median birth weight of 1220 g ( range , 760 - 1770 g ) and median gestational age at birth of 30 weeks ( range , 28 - 34 weeks ) were studied at a median postnatal age of 10 days ( range , 4 - 19 days ) . - pubmed
This may aid the timing of surgical intervention in preterm infants with a clinical diagnosis of NEC.gangrene , ischemia , MRI , necrotizing enterocolitis . - pubmed
PATIENTS : Forty - two patients underwent surgery for liver hemangiomas between January 1988 and December 1998 ; 41 were symptomatic . - pubmed
The primary indications for surgery were abdominal pain in 33 patients , diagnostic uncertainty in 6 , and enlargement in 3 . - pubmed
MAIN OUTCOME MEASURES : ( 1 ) Patients ' assessment of the effects of surgery on preoperative symptoms , ( 2 ) determination of whether any other pathological conditions were missed in the preoperative evaluation , ( 3 ) operative mortality and morbidity , and ( 4 ) recurrences . - pubmed
Hospital mortality and morbidity were 2.4 % ( bleeding from the biopsy site on a lesion evaluated as inoperable at laparotomy ; 1 patient ) and 12 % ( 5 patients ) , respectively . - pubmed
No other cause of pain could be identified during follow - up in the other patients . - pubmed
CONCLUSIONS : Elective surgery is indicated in a small subset of patients with hemangiomas because of abdominal pain , enlargement , and diagnostic uncertainty . - pubmed
This result indicated that the previously reported inhibition of type 1 diabetes in NOD mice carrying a functionally inactivated IFN - gamma receptor alpha - chain gene may have been due to a closely linked and previously unidentified diabetes resistance allele . - pubmed
We describe a 19 - year - old woman with fulminant hepatic failure due to acute hepatitis B infection who received a living donor liver transplant from her sister . - pubmed
Is the human papillomavirus DNA present in penile warts ? - pubmed
Infection with human papillomavirus ( HPV ) has been established to be a sexually transmitted disease , with a potential risk of intraepithelial neoplasia and invasive cancer , function of the genotype involved . - pubmed
Scraped cells from lesions of 27 men establishing various types of penile warts were investigated by PCR for HPV DNA detection . - pubmed
2 HPV6 and 7 HPV ND infections were determined . - pubmed
The findings in this study confirmed the HPV involvement in penile warts . - pubmed
PURPOSE : To report the clinical findings and surgical treatment of multifocal , bilateral orbital hemangiomas in a patient with the blue rubber bleb nevus syndrome , a rare vascular disorder characterized by distinctive cutaneous and visceral hemangiomas . - pubmed
RESULTS : A 36 - year - old female with multifocal , bilateral orbital lesions was seen with severe proptosis and decreased visual acuity of the left eye . - pubmed
[ Tobacco brand - related headache ] . - pubmed
INTRODUCTION : Tobacco smoking has been considered a risk factor for headache by some authors , while others disagree because of contradictory data . - pubmed
PATIENTS AND RESULTS : We describe the clinical aspects of eleven patients ( four men and seven women ) who presented to us with tobacco brand - related headaches . - pubmed
More studies will be necessary in order to discover the mechanism leading patients to tobacco brand - related headache . - pubmed
Dilatation of the cystic duct in patients with obstructive jaundice . - pubmed
BACKGROUND : It is well known that obstructive jaundice causes biliary dilatation , but sonographic ( US ) findings of the cystic duct in patients with obstructive jaundice are rarely reported . - pubmed
We addressed this issue in 51 abstinent patients with histories of severe chronic alcoholism utilizing the Minnesota Multiphasic Personality Inventory ( MMPI ) and the Halstead - Reitan Neuropsychological Test Battery ( HRNTB ) . - pubmed
One hundred seventy - four patients underwent surgery for perforated peptic ulcer . - pubmed
Levetiracetam is a new anti - epileptic drug that is currently not licensed for use in children . - pubmed
Studies in adults suggest that it may be a useful adjunctive treatment both in partial onset and generalised epilepsy . - pubmed
A retrospective case notes review of 26 children age 10 years and under with refractory epilepsy was undertaken to evaluate the efficacy and safety of the drug . - pubmed
The drug appeared to be most effective in children with partial onset seizures and least effective in those with myoclonic seizures . - pubmed
Sixty - one percent of patients showed a good response to levetiracetam with at least a 50 % reduction in seizure frequency with two of these 26 children with previously refractory epilepsy becoming seizure - free . - pubmed
We evaluated the clinical signs and treatment of 16 patients with postpolio syndrome . - pubmed
Surgery can alleviate many of the distressing symptoms in patients with metastatic colorectal carcinoma . - pubmed
Effect of Helicobacter pylori eradication on anti - thrombotic dose aspirin - induced gastroduodenal mucosal injury . - pubmed
BACKGROUND : Helicobacter pylori infection and non - steroidal anti - inflammatory drugs are two major causes of gastric injury but the effect of H. - pubmed
The aim of the present study was to investigate the effect of Helicobacter pylori eradication on gastroduodenal mucosal injury induced by antithrombotic doses of aspirin . - pubmed
CONCLUSION : Helicobacter pylori eradication may prevent medium - dose aspirin - induced gastroduodenal mucosal injury . - pubmed
BACKGROUND : We sought to investigate the incidence and risk of embolism after percutaneous balloon mitral commissurotomy ( PMC ) and delineated the necessity of the maze procedure in patients with atrial fibrillation ( AF ) . - pubmed
Next our current criteria for indication of the maze procedure , which included duration of AF less than 10 years , voltage of f wave on electrocardiography greater than 0.1 mV , cardiothoracic ratio less than 70 % , and left atrial dimension less than 70 mm , were applied to all patients . - pubmed
RESULTS : Thirty - eight patients suffered from embolic complications after PMC . - pubmed
Of these 33 patients experienced AF before intervention . - pubmed
The actuarial embolism - free rate at 10 years was 81.9 % in patients with AF before PMC and 92.9 % in patients with sinus rhythm before PMC ( p = 0.01 ) . - pubmed
In a comparative study of the selected patients the actuarial AF - free rates after MVS / maze were 89.9 % at 1 year and 85.7 % at 5 years and were significantly higher than those of 17.3 % at 1 year and 4.2 % at 5 years after PMC ( p & lt ; 0.0001 ) . - pubmed
Surgical treatment concomitant with the maze procedure may be beneficial for patients with AF . - pubmed
Patients with migraine with and without aura as classified by the International Headache Society were recruited to a double - blind placebo - controlled crossover study . - pubmed
Patients were instructed to treat two attacks of at least moderate pain severity , with at least a 7 day interval , using subcutaneous 100 microg octreotide or matching placebo . - pubmed
Modelling the headache response as a binomial determined by treatment , using the patient as the level 2 variable , and considering a possible period effect , and sex and migraine type as other variables of interest , subcutaneous octreotide was not significantly superior to placebo . - pubmed
At a certain point in development , axons in the mammalian CNS undergo a profound loss of intrinsic growth capacity , which leads to poor regeneration after injury . - pubmed
Their involvement in the pathogenesis of chronic arthritis is controversial , however , and so we examined their role in experimental antigen - induced arthritis in mice . - pubmed
Transfer of CD4+CD25 + cells into immunized mice at the time of induction of antigen - induced arthritis decreased the severity of disease but was not able to cure established arthritis . - pubmed
Transient attenuation of neuropathic manifestations in rats following lesion or reversible block of the lateral thalamic somatosensory nuclei . - pubmed
BACKGROUND AND AIMS : Nociceptive behavior in animal models for mononeuropathy has been shown to be altered by spinal tract lesions which suggest a possible supraspinal modulation . - pubmed
METHODS : Different groups of rats ( n = 5 - 6 ) were subjected to mononeuropathy , following the spared nerve injury model , known to produce sustained heat hyperalgesia and tactile and cold allodynia which peaked about 2 weeks after nerve injury . - pubmed
Oxidative stress in Helicobacter pylori - induced gastric cell injury . - pubmed
Helicobacter pylori induces decrease in antioxidant defense factors , such as GSH , mucus and constitutive nitric oxide ( NO ) , gastric mucosal injury and inflammation . - pubmed
We tested the efficacy of an FTI ( ABT-100 ) in Zmpste24 - deficient mice , a mouse model of progeria . - pubmed
The FTI - treated mice exhibited improved body weight , grip strength , bone integrity , and percent survival at 20 weeks of age . - pubmed
These results suggest that FTIs may have beneficial effects in humans with progeria . - pubmed
PATIENTS AND METHODS : In this retrospective study , the subjects were 158 patients with ischemic stroke , including 105 with a normal tHcy level and 53 with a high tHcy level . - pubmed
Classification of non - bacterial osteitis : retrospective study of clinical , immunological and genetic aspects in 89 patients . - pubmed
Patients with sterile osteitis were analysed to develop diagnostic criteria . - pubmed
METHODS : A total of 89 patients with non - bacterial inflammatory bone lesions were observed for a median of 49 months . - pubmed
Twenty percent of all the patients demonstrated associated autoimmune disorders , particularly of the skin and bowel . - pubmed
Autoimmune diseases in 40 % of all the families , multiply affected family members , linkage to 18q21 and mouse models strongly indicate a genetic basis for NBO . - pubmed
Two patients with subclavian vein thrombosis are presented in which a balloon venoplasty led to recanalization of the subclavian vein and complete remission of clinical symptoms . - pubmed
In patients with extreme symptoms and unsuccessful initial catheter - directed local thrombolysis , this non - operative approach can be considered despite known favourable spontaneous outcome of subclavian vein thrombosis . - pubmed
Fourteen patients had squamous cell carcinoma and one adenocarcinoma . - pubmed
coli O157 and non - O157 strains . - pubmed
The vero cell cytotoxicity assay detected VT - producing strains of E. - pubmed
coli isolates that were VT positive ( vero cell ) or VT - gene positive by PCR , 2.2 % , 2.2 % , 4.4 % and 6.7 % belonged to non - O157 strains O91 , O111 , O103 and O157 , respectively , as determined by the Dry spot test . - pubmed
In addition , the demonstration of VTEC strains in humans , VT gene in faecal samples and E. - pubmed
coli isolates as well as non - O157 VTEC strains of E. - pubmed
The problem of transporting a patient with AMI and cardiogenic shock to a distant site and the problem of emergency CABG in such high - risk patients is discussed . - pubmed
We genotyped 272 children with atopic asthma , 54 children with nonatopic asthma ( NAA ) , and 254 control children for allelic determinants at two polymorphic sites in the region at positions promoter - 318 C & gt ; T and exon 1 + 49 G & gt ; A using restriction fragment length polymorphism methods . - pubmed
In the current study , we performed strain rate , creep , and stress - relaxation experiments using porcine AVL under planar biaxial stretch and loaded to physiological levels ( 60 N / m equi - biaxial tension ) , with strain rates ranging from quasi - static to physiologic . - pubmed
Antifungal treatment was scheduled for patients suspected clinically , mycologically or cytologically as having candidal infection . - pubmed
Two years after the first operation the patient has no detectable tumor . - pubmed
METHODS : GI tract specimens were reviewed ( 221 total ; 93 esophageal , 55 gastric cardiac , 48 oxyntic , 7 antral , 8 small bowel , 6 colonic , 3 appendiceal , 1 anal ) from 71 patients ( 63 M , 8F ) , 38 to 84 years ( median , 55 y ) undergoing chemotherapy for esophageal , breast , or lung cancer who had all received taxanes at some time [ either paclitaxel ( Taxol , 55 patients ) or docetaxel ( Taxotere , 16 patients ) ] . - pubmed
RESULTS : Five samples had striking mitotic arrest mimicking HGD in non - neoplastic mucosa and were from the esophagus , gastric cardia , gastric body , gastric antrum , and appendix of 5 separate patients . - pubmed
On follow - up , in 3/5 patients with samples 1 day posttreatment , 1 had acute appendicitis ( died 180 d postappendectomy ) , 1 died a day later of metastases , and 1 was asymptomatic ( alive with metastatic disease at 126 d postbiopsy ) . - pubmed
We present here the history of a patient developing an isolated pulmonary hypertension related to the intake of pergolide . - pubmed
The treatment of acute respiratory infections in children with orally administered , unbuffered penicillin solutions . - pubmed
A significant proportion of patients with myocardial infarction are missed upon initial presentation to the emergency department . - pubmed
In conclusion , the 15 - lead ECG identified more patients with posterior myocardial wall ischemia because of temporary balloon occlusion of the LC than the 12 - lead ECG . - pubmed
All patients had associated renal insufficiency . - pubmed
Four patients ( 31 % ) had infection . - pubmed
The management of children with Hunter syndrome - a case study . - pubmed
Children with this debilitating disease can now be offered enzyme replacement therapy ( ERT ) with idursulfase to manage the signs and symptoms of the disease and to improve quality of life . - pubmed
The genotypes of ESBL producing strains largely remain unknown in India ; hence the present study was aimed to determine the occurrence of ESBLs in Escherichia coli and Klebsiella pneumoniae , their molecular types and associated risk factors in a tertiary care hospital . - pubmed
We investigated the possible combined effects of gallic acid and resveratrol , which are major antioxidants present in fruit , including grapes , on PC12 rat pheochromocytoma ( PC12 ) cell death . - pubmed
We present a case of an invasive Brenner tumor of the ovary in a woman greater than age 70 . - pubmed
CASE : A 77 - year - old woman presented with a rare , invasive Brenner tumor of the ovary . - pubmed
Although different in ecology and susceptibility to control , the African malaria vectors Anopheles gambiae sensu stricto and An . - pubmed
This suggests that prior research groups have used misidentified strains of Cop . - pubmed
minuta or fungal strains that were only distantly related to the Cop . - pubmed
CONCLUSION : The cyanoacrylate promoted a reliable fallopian tube obstruction without fibrosis in an animal model exhibiting a similar tube diameter to that found in women . - pubmed
Production of acute rheumatic - like heart lesions in mice . - pubmed
They were then evaluated together with the previously prepared UDP - furanoses for their anti - parasitic properties against Leishmania donovani promastigotes , one of the agents responsible for visceral leishmaniasis . - pubmed
In an effort to identify key regulators of the crosstalk between melanoma cells and the melanoma - skin microenvironment , primary and metastatic human melanoma cells were seeded into skin organ cultures ( SOCs ) and grown for two weeks . - pubmed
The differential protein abundances were calculated by spectral counting , the results of which provides evidence that cell - matrix and cell - adhesion molecules that are upregulated in the presence of these melanoma cells recapitulate proteomic data obtained from comparative analysis of human biopsies of invasive melanoma and a tissue sample of adjacent , noninvolved skin . - pubmed
A case is presented of a 43 - year - old man without pre - existing medical comorbidities who sustained atraumatic bilateral patellar tendon ruptures following a treatment course of fluoroquinolone medication . - pubmed
Additionally , infection is often asymptomatic and as such goes untreated , creating reservoirs of T. - pubmed
vaginalis could reduce the human costs ( pregnancy complications , infertility ) , medical costs ( repeated doctor visits , increased susceptibility to human immunodeficiency virus ( HIV ) infection ) , and societal costs ( stigma of STI , cycles of untreated infection ) associated with trichomoniasis . - pubmed
, a novel rapidly growing species related to the Mycobacterium terrae complex and associated with goat lung lesions . - pubmed
Early seizure detection in rats based on vagus nerve activity . - pubmed
Using left nerve VENG , seizures were detected in all PTZ - treated rats 103 + - 51 s ( mean + - SD ) before they developed tonic seizures . - pubmed
Control rats did not develop seizures and our method did also not detected seizures in these rats . - pubmed
Seizures can be early detecting based on left nerve VENG in anesthetized rats . - pubmed
Diaphragmatic hernia in the bovine ; case report . - pubmed
BACKGROUND : Treatment options for patients with inoperable primary or recurrent / metastatic abdominopelvic malignancies are limited , and these patients have short lifespan . - pubmed
METHODS : Consecutive 50 patients were identified from an Institutional Review Board ( IRB)-approved database undergoing ablation for unresectable abdominopelvic malignancies via conventional surgical methods in a single institution between 07/2003 and 09/2009 . - pubmed
RESULTS : Sixteen patients had primary tumors , and 34 presented with a recurrent / metastatic malignancy . - pubmed
The primary tumors were abdominopelvic sarcomas ( eight patients ) , large desmoids ( two ) , colorectal cancer ( CRC ) ( two ) , and gastric cancer , mucinous cystic pancreatic neoplasm , gastrointestinal stromal tumor ( GIST ) , and carcinoid ( one each ) . - pubmed
The recurrent / metastatic tumors were CRCs ( 16 patients ) , abdominopelvic sarcomas ( 12 ) , and GIST , prostate cancer , bladder cancer , melanoma , adrenal cancer , and pseudomyxoma peritonei recurrences ( 1 each ) . - pubmed
Patients with primary tumors had 5 - year survival of 18 % compared with no survivors at 5 years in the recurrent / metastatic group ( P = 0.002 ) . - pubmed
Patients with ablated primary tumors have a survival advantage over patients who have ablation for recurrent / metastatic disease . - pubmed
In the first investigation of this question , twenty nonverbal children with autism with a developmental age of 24 and 36 months , and twenty matched typical children , were presented with an experimental box requiring that a hierarchical sequence of subgoals be performed before it could be opened . - pubmed
The physiological parameters characterizing human capacities ( the ability to move , reproduce or perform tasks ) evolve with ageing : performance is limited at birth , increases to a maximum and then decreases back to zero at the day of death . - pubmed
METHODS : The model of experimental periodontitis of rats was established and treated by Bushenguchiwan with different doses . - pubmed
Humoral immune responses to rhesus lymphocryptovirus ( rhLCV ) lytic infection proteins were evaluated in the rhesus macaque animal model for Epstein - Barr virus ( EBV ) infection . - pubmed
The rhesus macaque animal provides a unique perspective on humoral responses to EBV infection in humans and can be a valuable model for EBV vaccine development . - pubmed
Incremental value of global systolic dyssynchrony in determining the occurrence of functional mitral regurgitation in patients with left ventricular systolic dysfunction . - pubmed
METHODS AND RESULTS : Patients ( n = 136 ) with LV systolic dysfunction ( ejection fraction & lt;50 % ) and at least mild MR were prospectively recruited . - pubmed
OBJECTIVE : To understand the level of blood - lipid and prevalence of dyslipidemia of children aged 3 to 6 in Tianjin , so as to provide evidence for large - scale blood screening strategy and to develop intervention of dyslipidemia and cardiovascular in children . - pubmed
Screening and intervention programs on dyslipidemia should be undertaken routinely in children , in order to prevent adult atherosclerosis and coronary heart disease . - pubmed
It is not clear whether centrally obese individuals exhibit greater cognitive impairment following acute stress . - pubmed
Polyposis registry clinicians across Europe recruited adolescents with FAP to receive aspirin ( 600 mg as 2 tablets / d ) and/or 30 g as 2 sachets / d in a 1:1 blend of potato starch and high amylose maize starch [ Hylon VII ] ) with placebo control for at least a year or until surgery before age 21 . - pubmed
Benefit assessment of non - drug treatment strategies in patients with essential hypertension : reduction in salt intake : Executive summary of rapid report A05 - 21B , Version 1.0 The aim of this investigation was to assess the benefit of interventions for reducing salt intake compared to interventions that are not intended to reduce salt intake in patients with essential hypertension with reference to patient - relevant outcomes and criteria used in blood pressure control . - pubmed
However , it has been reported that humans feel an illusory thermal sensation in conjunction with an apparently - thermal visual stimulus placed on a prosthetic hand in the rubber hand illusion ( RHI ) wherein an individual feels that a prosthetic ( rubber ) hand belongs to him / her . - pubmed
[ Application of trans - abdominal - mediastinal drainage tube in patients with high risk of esophagogastric or esophago - jejunal anastomotic leakage ] . - pubmed
METHODS : A total of 79 patients underwent thoraco - abdominal radical resection for gastric cardia cancer , with high risk of leakage of the anatsomosis , from Aug. 2007 to Aug. 2011 were included in this study . - pubmed
RESULTS : There was anastomotic leakage in four patients of the improvement group . - pubmed
One among those five patients had transdermal placement of thoracic drainage tube and was cured , and four among those five patients had second debridement operation , with 3 cured and one death case . - pubmed
CONCLUSIONS : Although putting trans - abdominal - mediastinal drainage tube can not prevent the leakage of esophagogastric or esophago - jejunnal anastomosis , it can reduce the systemic inflammatory responses , death and painful suffering of the patients caused by anastomotic leakage . - pubmed
An epidemiological survey on dogs was conducted applying serological methods in two Italian regions where angiostrongylosis is endemic in foxes . - pubmed
We retrospectively reviewed the endosonographic features of four patients with gastric schwannomas and their computed tomography imaging results . - pubmed
Disappearance of the radial pulse on palpation indicated the systolic arterial pressure , as Riva - Rocci confirmed by calibration experiments in animals and with human cadavers . - pubmed
Commensal Escherichia coli residing in the human gut produce colibactin , a small - molecule genotoxin of unknown structure that has been implicated in the development of colon cancer . - pubmed
Analysis of 1543 patients with advanced osteoarthritis of the hip . - pubmed
PATIENTS AND METHODS : The femoral neck length of 1543 patients with osteoarthritis grade 3 and 4 was measured on calibrated pelvic radiographs . - pubmed
OBJECTIVE : This study aims to examine whether blood pressure reductions differ by estrogen use among overweight glucose - intolerant women . - pubmed
METHODS : We conducted a secondary analysis of Diabetes Prevention Program postmenopausal participants who used oral estrogen with or without progestogen at baseline and 1 - year follow - up ( n = 324 ) versus those who did not use oral estrogen with or without progestogen at either time point ( n = 382 ) . - pubmed
CONCLUSIONS : Among overweight women with dysglycemia , the magnitude of blood pressure reductions after ILS is unrelated to postmenopausal estrogen use . - pubmed
BACKGROUND AND OBJECTIVES : Women 's use of alcohol in pregnancy is associated with an increased risk of fetal loss and birth defects . - pubmed
Acute gallbladder necrosis in a patient with acute type B aortic dissection . - pubmed
We experienced the case of a 42 - year - old woman who suffered from acute gallbladder necrosis that occurred the following day after the onset of acute type B aortic dissection . - pubmed
METHODS : We prospectively investigated six stable TBI patients who underwent cranioplasty more than 90 days after effective decompressive craniectomy . - pubmed
METHODS : Weight gain and parasympathetic nervous system activity were assessed in 30 preterm infants randomly assigned to a massage therapy group or to an exercise group . - pubmed
METHODS : Colorectal cancer tissues from patients with or without liver metastases were profiled to identify differentially expressed microRNA . - pubmed
Correlation between miR-181a expression , the most differentially expressed microRNA , between patients with and without liver metastasis , and its downstream target genes were investigated using qRT - PCR . - pubmed
UNLABELLED : The dietary exposure of the human population to the prions responsible for the bovine spongiform encephalopathy ( BSE ) epizooty has led to the emergence of variant Creutzfeldt - Jakob disease ( vCJD ) . - pubmed
Compared to the " gold - standard " RIII model routinely used for endpoint titration of vCJD / BSE prions , either method improved the sensitivity by & gt;2 orders of magnitude and allowed reevaluating the infectious titer of spleen from a vCJD individual at disease end stage to & gt;1,000 - fold - higher values . - pubmed
We conclude that hfMSCs could be used as a new source of cells to treat patients with osteogenic diseases , as well as to understand the mechanisms of immunosuppression by MSCs . - pubmed
This study aimed to examine the alterations in coagulation parameters involved at different steps of hemostasis in patients with Crohn ' s disease and ulcerative colitis , in comparison with healthy individuals . - pubmed
Alteration of immunoproteome profile of Echinococcus granulosus hydatid fluid with progression of cystic echinococcosis . - pubmed
BACKGROUND : Cystic echinococcosis ( CE ) , caused by Echinococcus granulosus metacestode , invokes a serious public health concern . - pubmed
Immunoproteome analysis combined with imaging studies may be practical in the differential diagnosis of CE from AE and other cystic lesions , as well as for staging CE , which are pertinent to establish appropriate patient management . - pubmed
Efficacy and safety of reslizumab in patients with moderate to severe eosinophilic asthma . - pubmed
BACKGROUND CONTEXT : New spinal interventions or implants have been tested on ex vivo or in vivo porcine spines , as they are readily available and have been accepted as a comparable model to human cadaver spines . - pubmed
Clinical and epidemiological differences between septic arthritis of the knee and hip caused by oxacillin - sensitive and -resistant s. - pubmed
OBJECTIVE : To establish the risk factors for joint infection by oxacillin - resistant Staphylococcus aureus ( MRSA ) using clinical and epidemiological data . - pubmed
This study investigated the effects of the ethanol extracts of mung bean testa ( MBT ) on the metabolic inflammation - induced lipogenesis in gastrocnemius muscle of KK - Ay diabese mice . - pubmed
Ethanol extracts of MBT were orally administered to diabese KK - Ay mice for 4 weeks after diet - induced obesity model was generated by feeding a 60 % high - fat diet for 3 weeks . - pubmed
A 71 - year - old man diagnosed with lung cancer in the right lower lobe with invasion to the middle lobe underwent right lower and middle lobectomy with mediastinal lymph node dissection . - pubmed
Chinese rhesus macaques ( CRMs ) are ideal experimental animals for studying the pathogenesis of human immunodeficiency virus ( HIV ) and simian immunodeficiency virus ( SIV ) and for vaccine research . - pubmed
SHIV89.6 has been reported to be an attenuated virus because , in most cases , SHIV89.6 infection only causes limited alteration of immune cells and tissues , and it has been used commonly for vaccine research . - pubmed
In this study , we found that 6 of 14 SHIV89.6 - infected CRMs died within 127 weeks after infection . - pubmed
BACKGROUND : Traditional approaches for nighttime glycemic control in glycogen storage disease type I ( GSDI ) include continuous tube feeding , or ingestion of uncooked corn starch ( CS ) at bedtime . - pubmed
The aim of this study was to evaluate whether stable nighttime glucose control can be achieved with other types of slowly digested carbohydrates in adult GSDI patients . - pubmed
CONCLUSION : Consumption of cooked pasta is a suitable and more palatable alternative to uncooked corn starch to achieve nighttime glucose control in adult patients with GSDI . - pubmed
An advanced level of understanding of the complex physiological function and control of the human body may be combined with skill in heat transfer analysis and design to develop life - saving and injury - healing medical devices . - pubmed
METHODS : A single center retrospective study of 96 patients with mRCC from December 2004 to August 2013 . - pubmed
Profiling of spatio - temporal characteristics of altered pain sensitivity ( evoked pain to mechanical and/or heat stimuli ) allows implications on the mechanisms likely active in a given patient , including peripheral or central sensitization , intraspinal or descending inhibition . - pubmed
Patterns of international normalized ratio values among new warfarin patients with nonvalvular atrial fibrillation . - pubmed
Limited information exists regarding the relationship between international normalized ratio ( INR ) control / stability and the discontinuation of warfarin therapy among patients with nonvalvular atrial fibrillation ( NVAF ) . - pubmed
strains isolated from human feces was examined in vitro against a wide range of Gram negative pathogenic strains isolated from 30 infant patients ( 3 days to 5 years old ) with diarrhea . - pubmed
strains , the largest spectrum of antimicrobial activity against 9 of the 18 enteropathogenic strains was revealed for a B. - pubmed
OBJECTIVES : To explore the relation between the baseline aortic valve gradient ( AVG ) as a continuous variable and clinical outcomes following transcatheter aortic valve implantation ( TAVI ) in general and specifically in patients with high - gradient aortic stenosis ( AS ) . - pubmed
Rutin ameliorates kidney interstitial fibrosis in rats with obstructive nephropathy . - pubmed
BACKGROUND AIMS : Critical limb ischemia ( CLI ) is a major health problem worldwide , affecting approximately 500 - 1000 people per million per annum . - pubmed
METHODS : A cohort study of patients undergoing surgery for PTC was undertaken . - pubmed
METHODS : Patients who underwent surgical management of ureterocele from 2003 to 2015 were identified ; those who received concomitant fluoroscopic RUC were selected for the case series . - pubmed
RESULTS : Of the 43 patients that underwent surgery for suspected ureterocele , 28 underwent cystoscopy + RUC ( 10 M : 18 F ) at a median age of 4.6 months and median follow - up of 37.0 months . - pubmed
We found that a subset of avian influenza viruses , including potentially pandemic H5N1 , H7N9 , and H9N2 viruses , could infect human pulmonary endothelial cells ( HULEC ) with high efficiency compared to human H1N1 or H3N2 viruses . - pubmed
Notably , certain avian influenza viruses have evolved to escape this restriction , possibly contributing to virus - induced pneumonia and severe lung disease in humans . - pubmed
IMPORTANCE : Avian influenza viruses , including H5N1 and H7N9 , have been associated with severe respiratory disease and fatal outcomes in humans . - pubmed
Although acute respiratory distress syndrome ( ARDS ) and progressive pulmonary endothelial damage are known to be present during severe human infections , the role of pulmonary endothelial cells in the pathogenesis of avian influenza virus infections is largely unknown . - pubmed
By comparing human seasonal influenza strains to avian influenza viruses , we provide greater insight into the interaction of influenza virus with human pulmonary endothelial cells . - pubmed
Overall , this study provides a mechanism by which human endothelial cells limit replication of human influenza virus strains , whereas avian influenza viruses overcome these restriction factors in this cell type . - pubmed
These patients were divided as patients with isolated carpal tunnel syndrome ( n = 337 ) or coincident carpal and cubital tunnel syndromes ( n = 178 ) , then characterized according to demographics , medical history , physical examination , and NCS results . - pubmed
The variables involved are routinely used to assess the cubital tunnel , and all component factors of the KB score were of equivalent clinical weight in assessing patients with potential coincident compression neuropathy . - pubmed
CH treatment was initiated but the patient maintained recurrence rates compatible with chronic CH , even after increasing verapamil to 460 mg / day . - pubmed
With this treatment the severity and recurrence of CH substantially decreased , despite the patient 's autonomous decision to take lithium only during the acute phase of the cluster . - pubmed
OBJECTIVE : The aim of this study was to evaluate the efficacy of a nutritional program , which is characterized by a different modulation of proteins , in adult patients with sarcopenic obesity . - pubmed
METHODS : We studied 18 obese women aged 41 - 74 years . - pubmed
CONCLUSIONS : In our study , sarcopenic obese patients with high - protein diet showed an improvement in muscle strength . - pubmed
Knowledge of physiological microhemodynamic values of bone and striated muscle in NSG mice makes it possible to analyze pathophysiological processes at these anatomic sites , such as tumor growth , tumor metastasis , and tumor microcirculation , as well as the response to therapeutic agents . - pubmed
Paraquat - Induced Movement Disorder in Relation to Oxidative Stress - Mediated Neurodegeneration in the Brain of Drosophila melanogaster . - pubmed
PQ has been shown to induce PD - like phenotype in experimental animals . - pubmed
Drosophila , a valuable laboratory model organism , is widely used to study neurodegenerative disorders including PD . - pubmed
The acute ( single dose ) PQ model of PD in Drosophila is associated with high mortality as well as reversibility of locomotor deficits and , therefore , does not replicate the disease phenotype . - pubmed
We have investigated the relevance of the acute and multiple ( sublethal ) dose of PQ to induce PD - like symptoms in Drosophila and shown that multiple - dose of PQ induces irreversible locomotor impairment without significant mortality . - pubmed
Our study has provided ultrastructural evidence for neurodegeneration involving mitochondrial damage in the brain caused by free radical - induced oxidative stress , which leads to locomotor impairment in Drosophila . - pubmed
The multiple ( sublethal ) dose of PQ could be an appropriate Drosophila model to induce PD - like symptoms of movement disorder associated with neurodegeneration , which could be useful to evaluate neuroprotective compounds . - pubmed
Psoriasis is a T - cell - mediated skin disease with autoimmune nature that is generally not observed in animals , this lack of a relevant experimental animal model of psoriasis has hindered the investigation of pathogenesis of disease . - pubmed
In this study , we present an IMQ animal model of psoriasis and designed a safe fusion peptide carrier , spherical nucleic acid gold nanoparticles conjugate , to improve penetration of the siRNA into the cells and skin and their targeting ability to gene regulation . - pubmed
Microscopic evaluation of mice back skin and immunohistochemistry process approved Inhibitory effect of SNA - NCs siRNA in the mouse model of psoriasis . - pubmed
Participants : Patients with PA ( n = 184 ) . - pubmed
Meta - analysis of adjunctive dexamethasone to improve clinical outcome of bacterial meningitis in children . - pubmed
Documents of randomized controlled trials ( RCT ) related to the treatment of bacterial meningitis in children with dexamethasone published since the establishment of the databases to December in 2016 were retrieved from the databases of Cochrane Library , Pubmed , MEDLINE , EMBASE , Chinese BioMedical Literature Database , and China National Knowledge Infrastructure . - pubmed
The results of meta - analysis have shown that patients who received dexamethasone have significantly lower risks in incidence of hearing loss ( OR = 0.68 , 95%CI 0.53 - 0.89 , P = 0.004 ) and severe neurological sequelae ( OR = 0.59 , 95%CI 0.37 - 0.95 , P = 0.03 ) , but the follow - up mortality is hardly effected ( OR = 0.86 , 95%CI 0.67 - 1.10 , P = 0.23 ) . - pubmed
CONCLUSIONS : Evidence has proven that the adjunctive administration of dexamethasone is conducive to treating children with bacterial meningitis to a certain extent , to decreasing the possibility of hearing loss and severe neurological sequelae , but has no significant effect on the follow - up mortality . - pubmed
Positive blood culture and inflammation at the vascular access site were highest in patients with nontunneled central lines ( 1.65 and 1.54/100 patient - months , respectively ) when compared to those with other types of vascular access . - pubmed
HYPOTHESIS : Differences occur in the prediction of cardiac events using 2D STE in AMI vs CAD patients . - pubmed
METHODS : In this prospective study , 94 patients with a first AMI and successful revascularization , and 137 patients with stable CAD after complete revascularization were included . - pubmed
Strain parameters in AMI and CAD patients were significantly different with respect to the occurrence of a cardiac event . - pubmed
CONCLUSIONS : Global strain parameters by 2D STE may be useful for the prediction of cardiac events in patients with CAD but add no supplemental information to baseline characteristic and ejection fraction in patients with AMI . - pubmed
We asked the patients about their pain and degree of satisfaction according to a visual analogue scale ( VAS ) , their memory of the procedure , mental status and the presence of uncomfortable symptoms on the day of the procedure and the day afterwards . - pubmed
No significant differences were found in the number of patients with pain ( VAS & gt;=1 ) , adverse events and discomfort between the two groups . - pubmed
: : The occurrence of MS at several unusual anatomic sites and its spectrum of morphologic patterns can result in significant diagnostic difficulty , and correct diagnosis is particularly important because of its high tendency to recur locally and to metastasize , which highlights the importance of diagnostic recognition , ancillary molecular genetic testing , and close clinical follow - up of patients with MS . - pubmed
BACKGROUND : Traumatic injury is well known to increase the risk of venous thromboembolic events ( VTEs ) , occurring in up to 58 % of trauma patients . - pubmed
RESULTS : A total of 2519 trauma patients were included with 97 ( 3.8 % ) developing VTE . - pubmed
GNF generates many electromagnetic hotspots as surface - enhanced Raman spectroscopy ( SERS ) excitation sources , and enables large - area visualization of molecular vibration fingerprints of metabolites in human cancer xenografts in livers of immunodeficient mice with sufficient sensitivity and uniformity . - pubmed
( 0.319 + - 0.028 h-1 for strain I09 and 0.397 + - 0.064 h-1 for strain I13 ) and Ps . - pubmed
Human clinical trials of & gt;= 10 patients with peri - implant diseases , treated with surgical or non - surgical approaches and laser therapy , and a follow - up period of & gt;= 6 months , were included . - pubmed
The prevalence and association of patients with impaired left ventricular ejection fraction and complete left bundle - branch block in Taiwan . - pubmed
Baseline clinical characteristics , electrocardiography and ECG parameters , in patients with cLBBB were compared among those with three different LVEFs ( EF & lt;35 % , 35%<= EF<50 % , and EF & gt;=50 % ) . - pubmed
Multivariable logistic regression analysis were conducted to identify independent predictors of impaired LVEF in patient with cLBBB . - pubmed
RESULTS : The prevalence of cLBBB was 0.4 % ( 648 patients ) , and it increased with age . - pubmed
The effects of age on the distributions of patients with cLBBB by three different EF statuses were significantly disparate . - pubmed
BACKGROUND : Until recently , the Chagas disease vector , Triatoma infestans , was widespread in Arequipa , Peru , but as a result of a decades - long campaign in which over 70,000 houses were treated with insecticides , infestation prevalence is now greatly reduced . - pubmed
Growth disturbance from a physeal injury is considered by many surgeons to be the most feared iatrogenic surgical complication after anterior cruciate ligament ( ACL ) reconstruction in skeletally immature patients , typically resulting in valgus , recurvatum , and/or a short limb . - pubmed
BACKGROUND : Dental trauma injuries are frequent in children and adolescents and can result in a sequela of future complications . - pubmed
Finally , acoustic angiography is employed to assess the consequences of taxane release at the tumor site in Nu / Nu - tumor - bearing mice . - pubmed
The median onset time of EBV reactivation was 49 days ( range , 14 - 561 ) , including five patients who developed post - transplant lymphoproliferative disorder ( EBV - PTLD ) . - pubmed
Twenty - one patients ( 17 % ) developed RTX - related neutropenia . - pubmed
Purpose : To compare the efficacy , safety , and potential advantages of the preservative - free versus preserved brimonidine % 0.15 preparations in patients with primer open - angle glaucoma ( POAG ) or ocular hypertension ( OHT).Methods : Forty - two eyes of the 21 treatment - naive patients with POAG or OHT were enrolled in this study . - pubmed
Ocular symptom values of the patients were evaluated with a scale of 0 - 4 ( 0 = no discomfort and 4 = severe discomfort).Results : Both of the brimonidine tartrate formulations resulted in statistically similar IOP reduction ( preserved formulation ; -5.2 mmHg [ 22.9 % reduction ] preservative - free formulation ; -5.7 mmHg [ 24.1 % reduction ] , p = 0.37 ) . - pubmed
A total of 60 patients ( 12.1 % ) died at 6 months [ 40 with anemia ( 17.5 % ) and 20 without anemia ( 7.5 % ) , P = 0.001 ] . - pubmed
The association of anemia and mortality was different according to frailty status , being significant in patients without frailty ( hazard ratio 3.94 , 95 % CI 1.84 - 8.45 , P = 0.001 ) , but not in frail patients ( hazard ratio 1.17 , 95 % CI 0.53 - 2.57 , P = 0.705 ) , ( P value for interaction = 0.035 ) . - pubmed
The association between anemia and mortality was especially significant in robust patients , whereas the poorer prognosis in frail patients was not modified by the presence of anemia . - pubmed
Underlying cancer must be ruled out in patients presenting with multiple subcutaneous nodules with suspicious history , physical , and radiological findings . - pubmed
Among patients with acquired TTP , the association between delayed plasma exchange and risk of death was evaluated using Cox regression . - pubmed
Acquired TTP was confirmed in 61 patients . - pubmed
36 % of suspected TTP and 13 % of confirmed TTP patients died . - pubmed
The results also showed that the nanoliposomes do not induce cytotoxicity and cell death in human MSCs and no perturbation of proliferation for all the times and the tested concentrations , as well as the combined nanoliposomes and hydrolysates ( HTS ) at a concentration of 0.1 mg / mL. - pubmed
Conclusion : Melatonin seems safe and effective for use in patients with SDs in early - stage cirrhosis in the short term . - pubmed
Nephrotoxicity of these compounds against human renal tubular epithelial ( HK-2 ) cells were evaluated using the MTT assay . - pubmed
CONCLUSIONS : In the largest national study to date , we found that thrombosis in NICU patients is associated with prematurity , low birth weight , sepsis , and invasive procedures . - pubmed
Shigella sonnei surface polysaccharides are well - established protective antigens against this major cause of diarrhoeal disease . - pubmed
Aqueous Extracts of Morus alba Root Bark and Cornus officinalis Fruit Protect against Osteoarthritis Symptoms in Testosterone - Deficient and Osteoarthritis - Induced Rats . - pubmed
We determined that the 12 - week consumption of MBW and CFW could alleviate testosterone - deficiency syndrome and osteoarthritis ( OA ) symptoms in testosterone - deficient rats , and the action mechanisms were explored . - pubmed
In conclusion , MBW , possibly CFW , could be effective alternative therapeutic agents for preventing osteoarthritis in testosterone - deficient elderly men . - pubmed
Respiratory and Reproductive Impairment of Commercial Layer Chickens After Experimental Infection with Gallibacterium anatis Biovar haemolytica . - pubmed
We used 500 base pairs of a 16S ribosomal RNA gene and the 16S-23S ribosomal RNA intergenic spacer , partial sequence in an experimental infection trial in commercial White Shaver layer chickens aged 19 wk . - pubmed
Severe lesions in the form of hemorrhagic pneumonia , catarrhal tracheitis , ovarian follicle and oviductal regression , and septicemia were evident on necropsy , demonstrating the pathogenicity of G. - pubmed
Methods : A cross - sectional study was conducted with 22 patients with IIH and 11 controls . - pubmed
Conclusion : The GCC was thinner in the patients with IIH compared to the controls , and there was an association between GCC and optic disc pallor . - pubmed
Letter : Treatment of allergy to cow 's milk . - pubmed
One hundred seventy - eight patients with transient ischemic attacks ( TIAs ) or small strokes with slight symptoms persisting for more than 24 hours ( incomplete recovery = IR ) ( TIA - IR ) from both the carotid and the vertebrobasilar systems were treated with anticoagulants . - pubmed
Only one patient had a lethal cerebral infarction when the thrombotest values were above the therapeutic level ; no other infarction happened during the treatment period . - pubmed
During the observation period , six patients had cerebral infarctions . - pubmed
All the cerebral infarctions were in patients who had their initial TIA / TIA - IR from the carotid territory ( within the same carotid artery which earlier had given symptoms ) . - pubmed
The investigation shows that long - term anticoagulant treatment is useful , especially in patients with carotid TIA / TIA - IR , and that this treatment should continue as long as the patients can manage it . - pubmed
Symptomatic osteonecrosis occurred in 8 out of 68 patients with systemic lupus erythematosus . - pubmed
Multiple joints were involved in 3 patients , and weight - bearing joints were most frequently affected . - pubmed
Osteonecrosis tended to occur early in the disease , and the patients had all received corticosteroids . - pubmed
Although development of gynecomastia in a patient with cancer may indicate persistence or regrowth of a tumor , we studied three patients with lymphoma in whom development of gynecomastia during or after chemotherapy did not portend a poor outcome . - pubmed
The serum estradiol level of one patient was elevated at the onset of gynecomastia , but it fell to normal as the gynecomastia resolved spontaneously over a three - month period during which the patient received no chemotherapy . - pubmed
In a second patient , gynecomastia resolved over a period of eight months while the patient continued on maintenance chemotherapy , and he remains clinically well in remission 21/2 years after onset of gynecomastia . - pubmed
In the third patient , gynecomastia developed while the patient was in complete remission and off of all therapy , and it remained unchanged for the duration of a 21/2 - year remission without therapy . - pubmed
To evaluate the extent and relative activity of the inflammatory process , we scanned patients with idiopathic pulmonary fibrosis using gallium-67 , a radionuclide known to concentrate in regions of inflammation . - pubmed
Evaluation of 67Ga scans in 30 patients with idiopathic pulmonary fibrosis and 19 control subjects demonstrated that the 67Ga - index in the group with idiopathic pulmonary fibrosis was significantly higher ( P less than 0.001 ) than that in the control group . - pubmed
When compared with lung biopsy morphologic studies in 22 patients with idiopathic pulmonary fibrosis , the 67Ga - index correlated with the degree of interstitial cellularity ( P less than 0.05 ) and the degree of alveolar cellularity ( P less than 0.005 ) . - pubmed
When compared with cellular analysis of bronchoalveolar lavage fluid in 17 patients with idiopathic pulmonary fibrosis , the 67Ga - index correlated with the differential percentage of neutrophils ( P less than 0.05 ) , but not lymphocytes , eosinophils , or macrophages . - pubmed
These studies indicate that 67Ga accumulates in the lungs of patients with idiopathic pulmonary fibrosis and is probably associated with the active inflammatory state . - pubmed
All dogs had frequent ventricular premature beats ( VPB ) and five of six dogs had ventricular tachycardia during the first 4 days after the cryolesion ; only one of the six dogs continued to have VPBs after 1 week , and this dog had identical VPBs before the creation of the cryolesion . - pubmed
Neither control dog had VPBs . - pubmed
VPBs in these animals were shown to originate at the border of the cryolesion . - pubmed
During an oral glucose tolerance test the 2 h plasma glucose value was significantly higher in patients with myotonic dystrophy compared to controls , and 5 out of the 7 patients demonstrated hyperinsulinemia . - pubmed
No effects such as changes in the patient 's BP , pulse rate and rectal temperature were noted during the observation period , and no side - effects such as pain , dyspnoea , nasal symptoms , exanthema or thrombophlebitis , nor any other symptoms to suggest that the solution was not well tolerated . - pubmed
Reversal of renal failure and control of hypertension in patients with occlusion of the renal artery . - pubmed
Results of arteriographic investigation of patients with deteriorating renal function or poorly controlled hypertension have revealed that thrombosis of the renal artery is not an uncommon exacerbating factor . - pubmed
Seventeen patients with one or more occluded renal arteries had an operation to improve renal function or to control hypertension . - pubmed
Stenosis of the contralateral renal artery was present in addition to the occlusion in four patients . - pubmed
Eight patients with renal failure had marked improvement in renal function after revascularization of the occluded renal arteries . - pubmed
Preoperative control of hypertension was difficult in 16 of the 17 patients . - pubmed
The hypertension was unchanged in two patients . - pubmed
Sepsis - related complications occurred in 51 patients ( 27.4 % ) , including 3 surgical deaths , 30 wound infections , and 18 others . - pubmed
For good coverage of cholangitis prior to operation , the proper antibiotic should have potency against gram - positive Enterococcus , gram - negative bacilli , especially Pseudomonas and E. - pubmed
An analysis of results of rheological properties of blood in 45 patients with different forms of postthrombotic disease of lower extremities has shown that 78 % of the patients have erythrocytosis and all the patients have hyperviscosity shifts . - pubmed
Thirteen patients with faecal incontinence and 26 control subjects were studied to investigate whether a quantitative electromyographic ( EMG ) signal could be correlated to anal manometry . - pubmed
Diphenoxylate - atropine ( Lomotil ) overdose in children : an update ( report of eight cases and review of the literature ) Eight pediatric accidental overdoses of diphenoxylate - atropine ( Lomotil ) are reported , and 28 literature cases are reviewed . - pubmed
Only 6 of 36 children showed signs of atropine overdose ( central nervous system excitement , hypertension , fever , flushed dry skin ) . - pubmed
The authors treated eight children with corticoid dependent syndrome caused by minor abnormalities of the glomeruli with Cyclosporin A. They administered Cyclosporin , 5 mg / kg/24 h. , for a period of 8 - 16 weeks . - pubmed
After initial infection with human immunodeficiency virus 1 ( HIV-1 ) , patients may remain asymptomatic for years before the onset of acquired immune deficiency syndrome ( AIDS ) . - pubmed
At present , it is not clear whether the immune abnormalities in either the asymptomatic phase or in clinical AIDS are due solely to direct effects of HIV-1 or whether they also reflect host immunoregulatory mechanisms . - pubmed
In this article , by Charles Via , Herbert Morse and Gene Shearer , the immune abnormalities associated with early HIV-1 infection are compared with immune abnormalities found in three murine models of autoimmunity and immunodeficiency , and it is suggested that host mechanisms contribute to defective helper T ( TH)-cell function early in the course of HIV-1 infection . - pubmed
Etiological factors for gastric cancer , among others , involve consumption of smoked , salted , and pickled fish of certain types . - pubmed
In rats , these amines induce cancer specifically in organs such as breast , colon , or pancreas , associated with Western - type nutrition where promotional elements such as dietary fat play an enhancing role . - pubmed
The patients who had an uncemented prosthesis had a significantly greater mean blood loss , both intraoperatively ( p less than or equal to 0.05 ) and during each subsequent eight - hour interval on the first postoperative day ( p less than or equal to 0.05 ) . - pubmed
When patients who had rheumatoid arthritis and osteoarthrosis were considered separately , the results were similar ; that is , there was a significantly greater total postoperative blood loss in each of the two groups when cement was not used ( p less than or equal to 0.025 ) . - pubmed
In addition , sodium excretion was measured in rats receiving lethal intestinal radiation injury . - pubmed
No recovery of these fluid compartments was observed in rats destined to die from intestinal radiation injury . - pubmed
Since the demonstration of a humoral antiplatelet factor which causes a transient ITP when given to healthy volunteers , ITP has been thought of as an autoimmune disease . - pubmed
In our multicenter studies for severe ITP ( less than 30 X 10(9)/liter platelet count ) in children , we observed the existence of at least two subgroups of ITP , namely rapid responders ( greater than or equal to 30 X 10(9)/liter platelet at 72 hours after the start of IVIG ) and slow responders ( less than 30 X 10(9)/liter platelet counts at 72 hours ) . - pubmed
Slow responding children were therefore comparable with adults with ITP . - pubmed
Because the adult type of ITP occurs often in young women , fetal risk must frequently be addressed . - pubmed
To ascertain our experience with traumatic perforations of the diaphragm , we reviewed the charts of 72 patients treated over a ten - year period . - pubmed
Replication of lymphocytic choriomeningitis virus in and clearance from the foot of the mouse . - pubmed
The hind foot was chosen for study of the mechanism by which adult mice clear lymphocytic choriomeningitis ( LCM ) virus . - pubmed
A dose of 10(5 ) mouse infectious units ( IU ) was optimal , and in all mouse strains tested foot swelling commenced 6 days after injection , with maximal response on days 7 and 8 . - pubmed
The rates of replication of the virus and its clearance were similar in the feet of mice of four strains tested , varying with regard to LCM virus - specific cell - mediated immunity . - pubmed
In CBA / J mice , virus elimination from the foot was followed for a longer time period and was incomplete up to 100 days after infection . - pubmed
Nineteen of these patients had presented with gastrointestinal hemorrhage at different postoperative intervals ( 4 days-23 years ) . - pubmed
We did Cybex testing of thirteen patients who had had a rupture of the distal tendon of the biceps brachii . - pubmed
In the presence of metastases no undetectable serum Tg result was found in patients off therapy , while four ( 6.9 % ) out of 58 samples from patients with bone and / or lung metastases and seven ( 31.8 % ) out of 22 samples from patients with lymph node metastases alone were undetectable ( falsely negative ) during suppressive therapy . - pubmed
Herpesvirus infection in burned patients . - pubmed
[ Chemically induced abnormalities of the masticatory skull in experimental animals . - pubmed
A 30 - year - old patient was operated on as an emergency because of a left atrial tumor . - pubmed
Leg contracture in mice : an assay of normal tissue response . - pubmed
Leg contracture , defined as the difference in extensibility of the control and irradiated hind legs of mice , was found to correlate with single doses of radiation from about 20 to 80 Gy . - pubmed
To determine the contribution of skin contraction to the overall leg contracture response , mice were sacrificed and the leg contracture measured before and after the removal of the skin of the leg . - pubmed
For that reason , a comparison was made of the immunogenicities of tumors induced with two doses of carcinogen in immunologically normal mice and in mice immunodepressed by adult thymectomy and irradiation . - pubmed
Although there was some increase in the immunogenicity of tumors induced in the immunosuppressed mice , the same relationship between carcinogen dose and immunogenicity was observed in both groups of mice . - pubmed
Mechanism of aspirin injury to human gastroduodenal mucosa . - pubmed
Gallium-67 scanning i patients with Crohn ' s disease : an aid to the diagnosis of abdominal abscess . - pubmed
In immune complex ( IC ) and autologous IC nephritis in rats , CCAq clearly inhibited the excretion of protein into urine and the elevation of blood urea nitrogen ( BUN ) . - pubmed
In the experiment employing NZB / NZW F1 mice , the proteinurea , the elevation of BUN level , and the production of antibodies were clearly inhibited by the administration of CCAq . - pubmed
Legg - Calve - Perthes disease in dogs : a comparison to human Legg - Culve - Perthes disease . - pubmed
The femoral heads of 12 dogs with naturally occurring Legg - Calve - Perthes disease were studied by light and electron microscopic techniques . - pubmed
One ( 7.1 % ) was an infection with both A. - pubmed
Heparin may be a superior alternative to warfarin for the prevention of thromboembolic disease in pregnant women with cardiac valve prostheses . - pubmed
Conversely , children having disruptive behavior with attention deficit hyperactivity disorder or disruptive behavior with oppoistional defiant disorder had 50 % lower suicide index than those with adjustment disorders with concomitant depression and higher adjusted TC levels ( 4.45 and 5.12 mmol / L , p = 0.0003). - pubmed
This is the first reported survival of a pediatric patient with thermal injury and ARDS by using ECMO for the treatment of respiratory failure . - pubmed
The independent impact of regional and total body composition and sex and thyroid hormone levels on resting energy expenditure ( REE ) was assessed in 121 healthy , overweight ( body mass index [ BMI ] , 25 to 42 kg / m2 ) , postmenopausal women ( aged 49 to 58 years ) . - pubmed
METHODS : Bronchial biopsy specimens were obtained from 27 clinically healthy subjects with no history of lung disease . - pubmed
RESULTS : Nine of the 27 subjects showed bronchial hyperresponsiveness as defined by a PC20FEV1 of & lt ; or = 8 mg / ml histamine . - pubmed
Segregated subjects with and without bronchial hyperresponsiveness showed no difference in spirometric results . - pubmed
Thus , major components of a physiological pattern that predisposes laboratory animals to sodium - sensitive experimental hypertension have now been observed to covary in ambulatory humans . - pubmed
Corticosteroid alteration of carboplatin - induced hematopoietic toxicity in a murine model . - pubmed
CA given subcutaneously at 0.5 mg / d per mouse for 7 days before CB reduced CB - induced mortality due to neutropenia from 88 % in controls to 14 % in CA - treated mice ( P & lt ; .05 ) . - pubmed
These findings suggest that treatment of mice with CA induces cellular resistance of hematopoietic precursors to platinum and , thus , reduces CB hematotoxicity . - pubmed
We present 16 patients with chronic osteomyelitis treated with radical debridement and immediate free muscle transfer using the latissimus dorsi muscle preferably . - pubmed
Patients with primary diseases that recur in the LTx ( hepatitis B and CA ) do less well following LTx , with 5 - year survival rates of 55 and 40 % , respectively ) . - pubmed
The initial migration and micromotion of the revision femoral stem stabilized with morselized impacted cancellous allograft and bone - cement and the influence of cement pressurization on fixation of the cement / allograft composite to the host were examined with human cadaver femurs . - pubmed
The effect of coenzyme Q10 on infarct size in a rabbit model of ischemia / reperfusion . - pubmed
We assessed whether coenzyme Q10 , administered intravenously either during or 1 h before ischemia , can limit infarct size in the rabbit . - pubmed
METHODS : Anesthetized open - chest rabbits were subjected to 30 min of coronary artery occlusion and 4 h of reperfusion . - pubmed
In Protocol 1 , 12 min after beginning of ischemia rabbits were randomized to intravenous infusion of 30 mg coenzyme Q10 ( Eisai Co. , Japan ) ( n = 10 ) or vehicle ( n = 10 ) . - pubmed
In Protocol 2 , rabbits were randomized to 30 mg coenzyme Q10 ( n = 6 ) or vehicle ( n = 6 ) treatment 60 min before ischemia . - pubmed
CONCLUSIONS : Coenzyme Q10 , administered acutely either during or 60 min before myocardial ischemia , does not attenuate infarct size in the rabbit . - pubmed
The hypocalcaemia - inducing potential of urological irrigating fluids was studied in 7 young men and in 10 prostatectomy patients . - pubmed
These results suggest that dilutional hypocalcaemia can be expected to coexist with hyponatraemia in patients who develop the transurethral resection syndrome . - pubmed
Successful reversal of diabetes by single donor isologous islet transplantation in a mouse model . - pubmed
In this paper , we describe the in vivo and in vitro findings on a patient with clinical features of a mild LAD-1 disorder , i.e. - pubmed
Noncardiogenic pulmonary edema in a patient with diabetic ketoacidosis . - pubmed
[ A 57 - year - old man complaining of dyspnea ] . - pubmed
In fact , new findings reveal depressor , vasodilator , and antihypertensive actions that may be more apparent in hypertensive animals or humans . - pubmed
Increased nonenzymatically glycosylated proteins in the vitreous humor of diabetic animals . - pubmed
We sought to determine whether glycation is increased in the vitreous humor of short - term diabetic cats ( 6 months ' duration ) and rabbits ( 2 months ' duration ) , using a nitroblue tetrazolium colorimetric assay for fructosamine . - pubmed
Vitreous protein fructosamine concentration was significantly higher in diabetic cats and rabbits , compared with that in control ( nondiabetic ) animals . - pubmed
These results indicate that glycation is increased in the vitreous humor of short - term diabetic animals , and therefore may be one of the initial triggers for clinically apparent diabetic retinopathy . - pubmed
Sixty subjects aged 21 - 65 years with a diagnosis of nonpsychotic anxiety or insomnia were included . - pubmed
Febrile convulsions , rat brains , and scientific pessimism . - pubmed
The effects of intraamniotic human neonatal urine and meconium on the intestines of the chick embryo with gastroschisis . - pubmed
An experimental study was performed to investigate the effects of intraamniotic human neonatal urine and diluted meconium on the intestines of chick embryo with gastroschisis . - pubmed
Histopathologic changes of intestines induced by intraamniotic diluted meconium are consistent with the ones described for human gastroschisis specimens . - pubmed
The mechanisms of chronic disease and recovery from relapses in experimental autoimmune encephalomyelitis ( EAE ) , an animal model of multiple sclerosis , are unknown . - pubmed
Methyl methacrylate toxicity in rat nasal epithelium : investigation of the time course of lesion development and recovery from short term vapour inhalation . - pubmed
An investigation of the time course of development and recovery of the nasal lesion induced in rats by inhalation of methyl methacrylate ( MMA ) was conducted . - pubmed
UNLABELLED : The effects of hypothyroid status on renal function have been poorly studied in children . - pubmed
We assessed the renal function of hypothyroid infants detected during neonatal mass screening for congenital hypothyroidism ( CH ) . - pubmed
Eighty hypothyroid infants and 20 age - matched normal infants for controls were enrolled . - pubmed
CONCLUSION : From these results we conclude that serum creatinine levels are elevated in congenitally hypothyroid infants . - pubmed
The possibility of impaired renal functions should be kept in mind when treating hypothyroid infants . - pubmed
OBJECTIVE : The purpose of this study was to describe the sonographic appearance of the common extensor origin in cadavers and asymptomatic volunteers , and to relate this appearance to the findings in patients with lateral epicondylitis . - pubmed
SUBJECTS AND METHODS : Seventy - two elbows in 71 patients with lateral epicondylitis were examined on sonography . - pubmed
Most of the patients ( 60/71 ) gave a history of repetitive microtrauma . - pubmed
CONCLUSION : Sonography of the common extensor origin can be used to confirm lateral epicondylitis in patients with lateral elbow pain and provide information about the severity of the disease . - pubmed
This shows the diverse origin of HIV-1 strains circulating in the United Kingdom and may have implications for antiretroviral drug resistance . - pubmed
Medical records of 99 patients with isolated EA , 101 with isolated anorectal malformations ( ARM ) and 15 with both EA and ARM , consecutively admitted to our unit , were reviewed . - pubmed
For C592 G , this phenotype was confirmed by transfer to different CMV strains and by restoration of full drug susceptibility after removal of the mutation . - pubmed
This report retrospectively reviews the presentation , management and outcome in 14 patients with intestinal malrotation . - pubmed
Children presenting with recurrent or persistent abdominal pain , vomiting or failure to thrive may well have malrotation and should be investigated promptly and the condition corrected to avoid midgut volvulus which is attended by significant morbidity and mortality . - pubmed
The anocutaneous reflex and urinary continence in children with myelomeningocele . - pubmed
OBJECTIVE : To examine the hypothesis that because most patients with myelomeningocele and a positive anocutaneous reflex have a competent sphincteric mechanism they are more likely to be continent on intermittent catheterization than those with a negative reflex , and to become so with less need for adjunctive surgical treatment . - pubmed
PATIENTS AND METHODS : The study included 111 patients with myelomeningocele treated for urinary incontinence ; their present means of treatment and the outcome achieved were assessed and related to the presence or absence of an anocutaneous reflex . - pubmed
The effect of vanadium in lowering blood glucose in diabetic animals is well established ; however , the exact mechanism of action of vanadium still eludes us . - pubmed
In the present study we found that the plasma glucose in streptozotocin ( STZ ) diabetic animals was restored to normal following treatment with a single dose of BMOV , an organic vanadium compound , given by oral gavage ( 0.6 mmol / kg ) , similar to the response with chronic BMOV treatment . - pubmed
The main objective of this study was to evaluate the effect of 4 ( 5 , 20 , 80 , and 120 microg / kg ) doses of rFVIIa on correction of PT and the time to achieve hemostasis in cirrhotic patients with coagulopathy who are undergoing laparoscopic liver biopsy . - pubmed
METHODS : Seventy - one patients ( parts I and II ) with advanced liver disease ( Child - Turcotte B or C ) , platelet count & gt ; or = 60,000 / mm3 , and PT in the range of 3 - 15 seconds above normal were included in the study . - pubmed
None of the patients required operative intervention or transfusion of blood / blood products to control bleeding . - pubmed
CONCLUSIONS : The results of this study suggest that treatment with rFVIIa may offer benefit for patients with liver disease undergoing laparoscopic biopsy . - pubmed
[ Prophylactic and therapeutic effect of oxymatrine on D - galactosamine - induced rat liver fibrosis ] . - pubmed
CONCLUSIONS : Oxymatrine shows prophylactic and therapeutic effect in D - galactosamine induced rat liver fibrosis . - pubmed
Acute effects of higher than customary doses of salmeterol and salbutamol in patients with acute exacerbation of COPD . - pubmed
In this study , we compared the acute effects of higher than customary doses of salmeterol and salbutamol in 20 patients with acute exacerbation of COPD . - pubmed
OBJECT : Radiosurgery is commonly used for the treatment of patients with glioma . - pubmed
The goal of this study was to evaluate the safety and efficacy of radiosurgery in the management of patients with oligodendrogliomas ( ODGs ) or mixed oligoastrocytomas ( OGAs ) . - pubmed
METHODS : A retrospective chart review of patients treated between May 1990 and January 2000 identified 18 patients ( 21 tumors ) with either an ODG ( 10 ) or a mixed OGA ( 11 ) who had undergone radiosurgery . - pubmed
Sixteen patients had undergone one or more tumor resections before radiosurgery ; in two patients biopsy sampling alone had been performed . - pubmed
Tumor grades at the most recent operation were Grade I ( one ) , Grade 2 ( one ) , Grade 3 ( 12 ) , and Grade 4 ( seven patients ) . - pubmed
CONCLUSIONS : For patients with oligoastroglial tumors that have failed to respond to conventional therapies , radiosurgery may provide some survival benefit . - pubmed
This experiment showed that Asthma - relieving decoction ( Dingchuan tang ) can protect experimental asthma that blending of histamine and acetylcholine caused ( P & lt ; 0.05 [ symbol : see text ] P & lt ; 0.01 ) , can resist external trachea smooth muscle 's contracting that histamine caused ( P & lt ; 0.01 ) , and can promote secretion of phenol red of rat 's respiratory tract ( P & lt ; 0.01 ) . - pubmed
The objective of this longitudinal prospective cohort study was to determine whether level of prenatal cocaine exposure , or the interaction between level of prenatal cocaine exposure and contextual risk variables , was associated with a higher rate of infant - caregiver insecure attachment and disorganized attachment , or with alterations in infant crying or avoidant behavior , after controlling for prenatal exposure to alcohol , tobacco , and marijuana , the quality of the proximal caregiving environment , and other covariates . - pubmed
OBJECTIVES : To document the causes of upper airway obstruction in a population of children with Down syndrome and to highlight the role of associated comorbidities . - pubmed
DESIGN AND SETTING : Review of 23 cases involving children with Down syndrome who were referred for upper airway obstruction over a 2(1/2)-year period to the Pediatric Otolaryngology Service of the University of New Mexico , Albuquerque . - pubmed
None of the children had subglottic stenosis . - pubmed
Laryngomalacia was the primary diagnosis in 10 children ( 43 % ) , 8 of whom were younger than 1 month . - pubmed
Obstructive sleep apnea was the primary diagnosis in 11 children ( 48 % ) , 8 of whom were older than 2 years . - pubmed
All children with obstructive sleep apnea and 4 children with laryngomalacia had a secondary ear , nose , and throat disorder . - pubmed
Gastroesophageal reflux was a comorbidity in 14 children ( 61 % ) . - pubmed
CONCLUSIONS : The causes , severity , and presentation of upper airway obstruction in children with Down syndrome are related to the age of the child and to associated comorbidities . - pubmed
Pathological physiology in human cancer . - pubmed
Correlations between behavior and urinary excretion of indole amines and catecholamines in schizophrenic patients as affected by drugs . - pubmed
The indications for imaging were : suspected compressive lesion of the anterior visual pathway in 57 patients ( 55.3 % ) , acquired ocular motility disturbance in 20 patients ( 19.4 % ) , suspected orbital pathology in 11 patients ( 10.6 % ) , cerebrovascular accident in nine patients ( 8.7 % ) , and six patients ( 5.8 % ) were imaged for either headache or sinusitis . - pubmed
Effects of maternally administered dexamethasone and acute hypoxemia at 0.7 gestation on blood pressure and placental perfusion in sheep . - pubmed
Glucocorticoid administration to women in premature labor significantly decreases preterm infant morbidity and mortality . - pubmed
Initial patient presentation may be a diagnostic dilemma to the family physician unfamiliar with testing methods for and the treatment and care of patients with MG . - pubmed
The author focuses on the clinical features , electrodiagnostic testing , and treatment of patients with MG . - pubmed
PD patients who were on stable and optimized dose of levodopa were included in this study . - pubmed
Maximum permissive dosage of lactose and lactitol for transitory diarrhea , and utilizable capacity for lactose in Japanese female adults . - pubmed
The maximum permissive dosage of lactose not to induce transitory diarrhea was 0.72 g / kg of body weight and that of lactitol was 0.36 g / kg of body weight in Japanese adults . - pubmed
Our goal is to create mutant lines that model human diseases and disease syndromes and to make the mutant mice available to the scientific research community . - pubmed
Within the eye domain , mice are screened for anterior and posterior segment abnormalities using slit - lamp biomicroscopy , indirect ophthalmoscopy , fundus photography , eye weight , histology , and immunohistochemistry . - pubmed
The aim of this study was to investigate scintigraphic , immunohistological and ultrastructural changes associated with radiation - induced dysfunction of the lachrymal gland in an established experimental animal model . - pubmed
MATERIALS AND METHODS : Eighty patients who were diagnosed with small bowel adenocarcinoma and treated at our institute between 1983 and 2003 were retrospectively reviewed . - pubmed
Only 51.3 % of patients were accurately proved preoperatively to have a malignancy by endoscopic biopsy . - pubmed
Lymph node metastasis was the only independent factor predicting poor disease - free survival in patients undergoing curative resection . - pubmed
In this study , we addressed this issue using the cell culture system of rat schwannoma cell line RT4 . - pubmed
For the clinical study , the width of the anterior portion of the bursa was measured in both positions in both shoulders of 27 patients referred because of shoulder pain and in eight asymptomatic volunteers . - pubmed
The objective was to evaluate the feasibility and efficacy of a short - term , multi - agent and dose intensive regimen in AIDS patients with Burkitt or Burkitt - like lymphoma ( BL / BLL ) and to compare its efficacy with that of a conventional regimen . - pubmed
This was a retrospective , multi - center cohort study of all HIV-1 - infected patients diagnosed with BL / BLL between 1990 - 2004 . - pubmed
In conclusion , the short and intensive GMALL protocol for B - ALL / NHL is feasible in patients with AIDS - BL / BLL . - pubmed
Insulin resistance , inflammatory biomarkers , and adipokines in patients with chronic kidney disease : effects of angiotensin II blockade . - pubmed
Patients with chronic kidney disease ( CKD ) present a high prevalence of insulin resistance ( IR ) . - pubmed
These data demonstrate that patients with CKD have a high prevalence of IR , metabolic syndrome , and chronic inflammation and that the administration of the ARB olmesartan improves IR and inflammation markers in these patients . - pubmed
Plasma adipokine levels that are related to several metabolic risk factors in patients with CKD were not modified by ARB therapy . - pubmed
These products were quantified in the plasma of patients with chronic renal failure before hemodialysis ( n = 6 ) , patients with chronic heart failure ( n = 6 ) and controls ( n = 6 ) . - pubmed
Do workers exposed to intermittent aircraft noise suffer from occupational deafness ? - pubmed
The subsequent reports demonstrate the utility of molecular cytogenetics and expression analyses to the clinical management of patients diagnosed with hematological malignancies . - pubmed
The objective of this study was to combine environmental and socio - economic factors to explain the spatial distribution of two emerging human diseases in Belgium , Puumala virus ( PUUV ) and Lyme borreliosis . - pubmed
RESULTS : Negative binomial regressions including a correction for spatial endogeneity show that the spatial distribution of PUUV and Lyme borreliosis infections are associated with a combination of factors linked to the vector and host populations , to human behaviours , and to landscape attributes . - pubmed
The spatial dependence resulting from a combination of endogenous and exogenous processes could be accounted for in the model on PUUV but not for Lyme borreliosis . - pubmed
The objective of this study was to investigate the effects of RYGBP and BPD - RYGBP , a variant of BPD with a lower rate of metabolic deficiencies than BPD , on DM2 and the major components of metabolic syndrome in patients with morbid obesity and DM2 . - pubmed
METHODS : The prospective database of our unit , from June 1994 until May 2006 , was analyzed and 137 patients with DM2 were found . - pubmed
CONCLUSIONS : RYGBP and BPD - RYGBP are safe and lead to normalization of blood glucose , lipids , uric acid , liver enzymes and arterial pressure in the majority of patients , although this variant of BPD was more effective than RYGBP . - pubmed
We suggest that further studies should also investigate its usefulness in patients with milder degrees of obesity , DM2 and metabolic syndrome . - pubmed
MATERIALS AND METHODS : Eighty - three consecutive patients with right ventricular outflow tract dysfunction ( 5 - 41 years , 76 % tetralogy of Fallot ) referred to our center for cardiovascular magnetic resonance were studied . - pubmed
Susceptibility to impulse noise trauma in different species : guinea pig , rat and mouse . - pubmed
OBJECTIVE : To test the hypothesis that there is different susceptibility to impulse noise trauma in three species : the guinea pig , rat and mouse . - pubmed
Melioidosis is caused by the facultative intracellular bacterium , Burkholderia pseudomallei . - pubmed
This study has demonstrated that in vivo depletion of macrophages renders C57BL / 6 mice highly susceptible to intranasal infection with B. - pubmed
Compared with control mice , increased bacterial loads were demonstrated in spleen and liver of knockout mice at day 2 postinfection , correlating with increased inflammatory infiltrates comprised predominantly of neutrophils and widespread necrosis . - pubmed
Following infection with B. - pubmed
If so , then those with schizophrenia may have older fathers , since advancing paternal age is the major source of new mutations in humans . - pubmed
In order to tailor the best treatment in both newly diagnosed MS patients and those already receiving treatment , the neurologist must carefully consider the risk of treating non - responders . - pubmed
Palliating delirium in patients with cancer . - pubmed
Zoledronic acid reduces recurrent clinical fracture in patients with hip fracture . - pubmed
Preclinical studies in animal models have given encouraging results , and synthetic peptide - based intervention in human autoimmune rheumatic diseases is now approaching translational work into clinical settings . - pubmed
Still another lineage contained the two subgenera Parasorghum and Stiposorghum with 2n=10 species and their polyploid relatives with relatively large chromosomes ; ( 2 ) geographical divergence clearly existed in the S. - pubmed
Children with autism exhibit impairment in the processing of socioemotional information . - pubmed
We collected structural and functional magnetic resonance images ( MRI ) in children 8 to 12 years of age with high - functioning autism ( n=12 ) and typical development ( n=15 ) . - pubmed
The results showed that children with autism exhibited intact emotion matching , while showing diminished activation of the fusiform gyrus ( FG ) and the amygdala . - pubmed
It has been shown that a lytic fluid for dysentery bacilli can be obtained from the peritoneum of the guinea pig by intraperitoneal inoculation of live dysentery bacilli , and that the lytic action of such a fluid is not strictly specific , but that it exerts a group action on the dysentery - colon - typhoid group of bacilli . - pubmed
It is conceivable that the resistant strains are responsible for the untoward outcome of disease in human beings . - pubmed
Stem cells in the adult rat spinal cord : plasticity after injury and treadmill training exercise . - pubmed
Most are found incidentally and rupture in the nonpregnant patient has an approximate 25 to 36 % mortality rate . - pubmed
METHODS : We present the case of a 43 - year - old man with a recent episode of bacterial endocarditis with an incidental finding of a large 6 - cm splenic artery aneurysm . - pubmed
Two dithiolethiones have been evaluated in humans for cancer prevention . - pubmed
Here we have determined in the DIO mouse model the efficacy of a related small molecule compound , Genz-112638 , which is currently being evaluated clinically for the treatment of Gaucher disease , a lysosomal storage disorder . - pubmed
Whole body adiposity was not affected in normal mice , but decreased in drug - treated obese mice . - pubmed
RESULTS : Nerve swelling , considered significant when an increase in cross - sectional area was & gt ; or = 75 % , was observed in 43 patients . - pubmed
Nerve swelling associated with a circumferential LA spread image , present in 37 patients , was associated with a sensory success rate of 86 % . - pubmed
SUMMARY : It is apparent that subarachnoid clots play an important role in the development of delayed vasospasm that is one of the major causes of mortality and morbidity in patients with acutely ruptured cerebral aneurysm . - pubmed
SUMMARYStaphylococcus aureus is a leading cause of infections in deployed service members . - pubmed
Anxiety / stress among mothers living with HIV : effects on parenting skills and child outcomes . - pubmed
PATIENTS AND METHODS : For immunohistochemical studies , tissues from 46 patients with LSCC at the Dr. Lutfi Kirdar Kartal Education and Research Hospital were used . - pubmed
The main reason for ICU admission was septic shock in 22 patients ( 55 % ) . - pubmed
With the double objective of searching for a physiological brain circuit concerned with time estimation and establishing whether this circuit is dysfunctional in schizophrenia patients , we carried out an activation likelihood estimate ( ALE ) meta - analysis of published functional neuroimaging studies . - pubmed
In schizophrenia patients , the analysis indicates significantly lower activation of most right hemisphere regions of the circuit , suggesting that it may be subject to a pattern of disconnectivity . - pubmed
ADHD and epilepsy common are both common childhood disorders and both can have significant negative consequences on a child 's behavioural , learning , and social development . - pubmed
Children with epilepsy are at significant risk for ADHD and there is a need for more studies focussing on safe and efficacious interventions for symptoms of ADHD in this population . - pubmed
Studies using rodent models indicate that oscillatory phase - locking is disturbed in schizophrenia , emphasizing the need for more studies of oscillatory synchrony in the hippocampal - prefrontal network . - pubmed
Water samples were spiked at levels of 10(1 ) , 10(2 ) , 10(3 ) , and 10(4 ) CFU/100 ml with three - strain cocktails of either E. - pubmed
Six months after the surgery the patient is symptom - free and without signs of recurrence . - pubmed
However , it must be considered in the differential diagnosis , especially in middle - aged male patients without evidence of atherosclerotic disease in whom intermittent claudication has developed suddenly with a rapid progression or with fluctuation in severity . - pubmed
METHODS : All fecal samples were examined with the formol ethyl acetate sedimentation method for helminth ova and protozoan cysts . - pubmed
High and low consumption of soybeans as well as of sunflower and pumpkin seeds were associated with significantly reduced breast cancer risk compared to no consumption ( OR = 0.83 , 95 % CI = 0.70 - 0.97 ; and OR = 0.66 , 95 % CI = 0.77 - 0.97 , respectively ) . - pubmed
Our results provide evidence for a reduced postmenopausal breast cancer risk associated with increased consumption of sunflower and pumpkin seeds and soybeans . - pubmed
Effect of adjuvant chemotherapy on survival of patients with stage III colon cancer diagnosed after age 75 years . - pubmed
Genetic characterization and construction of an auxotrophic strain of Saccharomyces cerevisiae JP1 , a Brazilian industrial yeast strain for bioethanol production . - pubmed
Yeast strains have acquired distinct characteristics that are the result of evolutionary adaptation to the stresses of industrial ethanol production . - pubmed
cerevisiae strain isolated from a sugarcane mill and is becoming increasingly popular for bioethanol production in Brazil . - pubmed
Emerging infectious diseases ( EIDs ) pose a significant threat to human health , economic stability , and biodiversity . - pubmed
Here , we highlight the emergence of a zoonotic Henipavirus , Nipah virus , to demonstrate the interdisciplinary and macroecological approaches necessary to understand EID emergence . - pubmed
We aimed to investigated the serum miRNA profile in pertussis patients and explored its potential as a novel diagnostic biomarker for pertussis . - pubmed
Among 664 different miRNAs analyzed using a miRNA array , 50 were overexpressed and 81 were underexpressed in the serum of pertussis patients . - pubmed
A panel of five miRNAs ( miR-202 , miR-342 - 5p , miR-206 , miR-487b , miR-576 - 5p ) was confirmed overexpressed in pertussis patients ( p & lt ; 0.05 ) . - pubmed
Risperidone - induced paroxysmal perceptual alteration in a child with autism . - pubmed
BACKGROUND : Hyperthermic intraperitoneal chemotherapy ( HIPEC ) is more and more used in the treatment of patients with peritoneal carcinomatosis ( PC ) of different primary tumours . - pubmed
However , survival of patients with PC is still poor . - pubmed
MATERIALS AND METHODS : A model for peritoneal carcinomatosis of colorectal origin was created by implantation of tumour fragments ( HT29 ) in the abdomen of athymic nude rats . - pubmed
Ocular manifestations and visual functions in patients with Fanconi anaemia . - pubmed
METHODS : Ten patients with FA , ages 8 - 17 years , underwent ophthalmological examinations , corneal , periocular and fundus photography , visual evoked potentials ( VEPs ) , visual fields and ocular motor and visual processing information tests . - pubmed
Microcornea was present in 18 of 18 eyes , short axial lengths in six of six eyes , steep corneal curvatures in four of six eyes , ptosis in 14 of 16 eyes , short palpebral fissures in 15 of 16 eyes and hypotelorism in three of seven patients . - pubmed
Eight patients had ocular motor dysfunction , while nine of 10 patients showed delay in visual processing skills . - pubmed
CONCLUSION : Patients with FA can present with microcornea , microphthalmia , ptosis , steep corneal curvatures , small optic discs , ptosis and delay in visual processing skills . - pubmed
Supplemental parenteral nutrition in critically ill patients . - pubmed
Different from classical strain engineering approaches , this work was initiated to improve E. - pubmed
To test whether structural integrity of this fronto - striato - thalamic circuit can account for executive impairments in TBI we automatically segmented the thalamus , putamen and caudate of 25 patients and 21 healthy controls and obtained diffusion weighted images . - pubmed
A 77 - year - old woman with Stage IV gastric cancer was admitted to our hospital because of high fever , poor appetite , and abdominal pain during combined chemotherapy with S-1 and cisplatin ( CDDP ) . - pubmed
BACKGROUND : Challenging anatomy for carotid artery access can result in a delay to achieve successful recanalization in patients with acute ischemic stroke . - pubmed
In patients , chronic treatment with lithium leads to renal microcysts and nephrogenic diabetes insipidus ( NDI ) . - pubmed
Kidney microcysts were induced in male adolescent rats by feeding dams with lithium ( 50 mmol / kg chow ) from postnatal days 7 - 34 . - pubmed
OBJECTIVE : The purpose of this work was to review the diagnosis , management , and outcomes of patients with perianal Paget ' s disease . - pubmed
PATIENTS : Sixty - five patients with perianal Paget ' s disease were included in the study ( 35 women [ 54 % ] ; median age at diagnosis , 66 years [ range , 60 - 72 years ] ; and 41 with invasive disease/24 with noninvasive disease ) . - pubmed
Synchronous malignancies unrelated to the primary disease were noted in 5 patients with invasive disease and 3 with noninvasive disease . - pubmed
Forty - one patients ( 27 invasive and 14 noninvasive ) required multiple operations for tumor clearance . - pubmed
Untreated brain arteriovenous malformation : patient - level meta - analysis of hemorrhage predictors . - pubmed
We censored patients at first treatment , death , last visit , or 10 - year follow - up , and performed stratified Cox regression analysis of time - to - hemorrhage after evaluating hemorrhagic presentation , sex , age at diagnosis , deep venous drainage , and AVM size as predictors . - pubmed
RESULTS : A total of 141 hemorrhage events occurred during 6,074 patient - years of follow - up ( annual rate of 2.3 % , 95 % confidence interval [ CI ] 2.0%-2.7 % ) , higher for ruptured ( 4.8 % , 3.9%-5.9 % ) than unruptured ( 1.3 % , 1.0%-1.7 % ) AVMs at presentation . - pubmed
The structure - activity relationship of these compounds was investigated , leading to the identification of compound 28 , which demonstrated favorable pharmacokinetic properties in mice and good antitumor activities in the human glioma xenograft model in athymic nude mice . - pubmed
Transgenic mice that express the HCV core protein develop HCC after the steatosis stage and produce an excess of hepatic reactive oxygen species ( ROS ) . - pubmed
Taken together , these results indicate that Ca ( 2 + ) uniporter - mediated mitochondrial accumulation of iron exacerbates hepatocyte toxicity caused by the HCV core protein . - pubmed
Erythropoiesis - stimulating agents did not act directly upon isolated tumor cells to stimulate pathways known to promote proliferation or survival of human tumor cells isolated from primary and metastatic tumor tissues . - pubmed
MicroRNA-150 protects the mouse heart from ischaemic injury by regulating cell death . - pubmed
For example , miR-150 is down - regulated in patients with acute myocardial infarction , atrial fibrillation , dilated and ischaemic cardiomyopathy as well as in various mouse heart failure ( HF ) models . - pubmed
METHODS AND RESULTS : Here , we show that genetic deletion of miR-150 in mice causes abnormalities in cardiac structural and functional remodelling after MI . - pubmed
Assessing the abundance , seasonal questing activity , and Borrelia and tick - borne encephalitis virus ( TBEV ) prevalence of Ixodes ricinus ticks in a Lyme borreliosis endemic area in Southwest Finland . - pubmed
and tick - borne encephalitis virus ( TBEV ) prevalence were evaluated in a Lyme borreliosis endemic area in Southwest Finland , Seili Island , where a previous study mapping tick densities was conducted 12 years earlier . - pubmed
High levels of regulatory T cells in blood are a poor prognostic factor in patients with diffuse large B - cell lymphoma . - pubmed
METHODS : Peripheral blood samples from 77 patients with DLBCL and 30 healthy volunteers were analyzed using flow cytometry immunophenotyping . - pubmed
CONCLUSIONS : Changes in blood immune cells occur in patients with DLBCL . - pubmed
METHODS : From January 1 , 2007 to December 31 , 2009 , 37 patients who had Hartofilakidis type B developmental dysplasia of the hip underwent a primary total hip arthroplasty using a high hip center technique . - pubmed
Four patients continued to present with Trendelenburg gait pattern at the last follow - up . - pubmed
Patients with ECRS present with thick mucus production , long - term nasal congestion , loss of sense of smell , and intermittent acute exacerbations secondary to bacterial infections . - pubmed
Demographics of tuberculosis of spine and factors affecting neurological improvement in patients suffering from tuberculosis of spine : a retrospective analysis of 312 cases . - pubmed
On statistical analysis , although three groups of patients with complete improvement , partial improvement and no improvement were similar in age , sex , radiological presentation , and co - morbidities and the presence of pulmonary tuberculosis , they were significantly different with regard to the levels of vertebral involvement , AIS grade at presentation , bladder and bowel involvement and its duration . - pubmed
CONCLUSIONS : In management of patients suffering from tuberculosis of spine , levels of vertebral involvement , AIS grade at presentation , bladder and bowel involvement and its duration significantly affect the final neurological improvement . - pubmed
Abstract The principles of rational antibacterial therapy in children for the burn trauma were analyzed . - pubmed
The results of the completed treatment of 808 children for the burn trauma in a Combustiological Department of Municipal clinical hospital of City of Zaporozhye were studied . - pubmed
Prescription of modern anticlostridial probiotics , containing stamms of Lactobacillus rhamnosus R0011 and Lactobacillus acedofilus R0052 , on background of continuing antibacterial therapy , have constituted the effective measure of prophylaxis for the antibiotic - associated diarrhea , as the most frequent complication of antibacterial therapy . - pubmed
Despite significant technological advances , rheumatoid arthritis remains an incurable disease with great impact on the life quality of patients . - pubmed
Letter in response to : Identifying risk in the use of tumor markers to improve patient safety . - pubmed
In this study , 829 diverse compounds with rat carcinogenicity were collected from Carcinogenic Potency Database ( CPDB ) . - pubmed
Furthermore , the best binary and ternary classification models were used to estimate carcinogenicity of tobacco smoke components containing 2251 compounds . - pubmed
There were more early - stage cancer patients in U group than in M group . - pubmed
Serosurvey of Coxiella burnetii ( Q fever ) in Dromedary Camels ( Camelus dromedarius ) in Laikipia County , Kenya . - pubmed
We evaluated the seroprevalence of a significant zoonotic pathogen , Coxiella burnetii ( Q fever ) , among 334 camels from nine herds in Laikipia County , Kenya . - pubmed
This study was conducted as a randomized clinical trial on 18 patients ( divided into two groups ) after surgical correction of Acute Aortic Aneurysm ( AAA ) . - pubmed
However , three of the five selected compounds ( 6 , 23 , and 26 ) exhibited relatively high cytotoxicity in mouse fibroblasts at micromolar concentrations . - pubmed
The selected thio - sugars are very promising compounds , thus making them candidates for further modifications that would decrease their cytotoxicity against eukaryotic cells without affecting their antimycobacterial potential . - pubmed
In addition , they establish a murine model for studying the potential impact of this dysbiosis on host resistance and physiology . - pubmed
METHODS : We retrospectively reviewed 86 patients with HCC ( 35 female , 51 male ) managed in our institution between 2009 and 2014 . - pubmed
SUBJECTS / METHODS : We fed C57BL6 mice a high - fat diet to generate obesity and then switched the diet to a lower - fat diet to induce weight loss . - pubmed
We then measured circulating levels of PGD2 in obese patients before and after weight loss and found that while elevated relative to lean subjects , levels of this metabolite did not decrease after significant weight loss . - pubmed
A 67 - year - old man with coronary artery disease and previous coronary underwent successful Guideliner reverse CART percutaneous coronary intervention of a chronic total occlusion of the right coronary artery . - pubmed
Despite these dramatic findings , the patient remained hemodynamically stable and pain - free , with resolving ECG changes . - pubmed
Anesthesia management of a patient with a femoral neck fracture and hered - itary hemorrhagic telangiectasia . - pubmed
Literature regarding anesthesia and perioperative management of such patients is limited , with no published papers for orthopedic surgery in patients with HHT . - pubmed
CASE REPORT : An 82 - year - old HHT female patient with femoral neck fracture was scheduled for hemiarthroplasty . - pubmed
CONCLUSION : Patients with HHT require careful preoperative evaluation to identify and appreciate possible symptoms as well as to assess their pulmonary and cardiac function accurately . - pubmed
Patients with advanced ALN metastases were more likely to have a higher number ( & gt;=2 ) of positive LNs ( OR , 8.06 ; P = 0.015 ) on restaging MR imaging . - pubmed
INTRODUCTION : The purpose of this study was to evaluate clinical outcomes in children with asymptomatic congenital lung malformations ( CLM ) who were initially managed nonoperatively . - pubmed
Objective : To observe the effect of hyperbaric oxygen therapy for the inflammation of rabbit nasal in postoperation period , to investigate the clinical feasibility of hyperbaric oxygen therapy in reducing the inflammatory reaction and promoting mucosal healing in nasal recovery stage after surgery . - pubmed
Aesthetic outcomes and morphological changes in chin parameters after mandibular distraction and subsequent advancement genioplasty in patients with mandibular micrognathia . - pubmed
This study addressed lower facial third aesthetics in a consecutive series of subjects with micrognathia who underwent MDO and subsequent advancement genioplasty . - pubmed
Pre - genioplasty cephalometric measurements showed that all patients had a deficient chin position and projection ; they were dissatisfied with their facial aesthetics . - pubmed
In this study , we examined how PHOSPHO1 deficiency might affect the healing and quality of fracture callus in mice . - pubmed
Fractures were allowed to heal for four weeks and then the mice were euthanized and their tibias analyzed using radiographs , micro - CT ( muCT ) , histology , histomorphometry and three - point bending tests . - pubmed
This included 8 patients with mid - shaft tibial fractures and 6 intact cadaveric legs . - pubmed
PARTICIPANTS : A total of 104 patients complaining of neck or arm pain with no prior surgical history and who had undergone a CNRB at an outpatient clinic from May 2015 to December 2017 were included . - pubmed
The writing group reaffirmed the 2015 pediatric advanced life support guideline recommendation that either lidocaine or amiodarone may be used to treat pediatric patients with shock - refractory ventricular fibrillation or pulseless ventricular tachycardia . - pubmed
Reply to the Editor- The site of origin of the ventricular premature beat in a patient with 2 different P - wave morphologies . - pubmed
CONCLUSIONS : The observed mortality in the intubated children 1 - 6 years old suffering from severe TBI seemed to be higher than expected . - pubmed
Unilateral Osteotomy of Lumbar Facet Joint Induces a Mouse Model of Lumbar Facet Joint Osteoarthritis . - pubmed
The establish of animal models highly mimicking the clinical conditions is a useful tool for the investigation of LFJ OA . - pubmed
However , the previously established animal models damaged the LFJ structure directly , which did not demonstrate the effect of aberrant mechanical loading on the development of LFJ osteoarthritis . - pubmed
METHODS : In the present study , an animal model for LFJ degeneration was established by the unilateral osteotomy of LFJ ( OLFJ ) in L4/5 unit to induce the spine instability . - pubmed
Effect of resveratrol on the radiosensitivity of 5 - FU in human breast cancer MCF-7 cells . - pubmed
OBJECTIVE : To analyze the clinical characteristics and drug resistance in patients with non - tuberculous mycobacteria ( NTM ) pulmonary disease in Changsha Central Hospital of Hunan Province in recent three years . - pubmed
Mycobacterium avium - intracellulare ( 56.21 % ) and mycobacterium chelonae - abscess ( 20.92 % ) were the majority . - pubmed
We report here a case of an immunocompetent patient suffering from recurrent epithelial herpetic keratitis associated with the emergence of antiviral resistance . - pubmed
Safety , effectiveness , and health care cost comparisons among elderly patients with venous thromboembolism prescribed warfarin or apixaban in the United States Medicare population . - pubmed
We retrospectively summarized the clinical characteristics of patients with cesarean scar pregnancy and explored the advantages and disadvantages of fertility - preservation treatment method . - pubmed
145 patients underwent transvaginal clearance , 33 patients underwent endoscopic surgery , and 26 patients underwent uterine artery embolism . - pubmed
Conclusion : Transvaginal clearance is an effective and relatively safe treatment option for patients with cesarean scar pregnancy . - pubmed
Of note , patients whose biopsy is performed at a specialized musculoskeletal tumor center benefit in terms of improved local tumor control . - pubmed
These data indicate that the mPFC is responsible for the social recognition deficit in the transgenic mice , and provide new insight into potential therapies for MECP2 duplication syndrome . - pubmed
METHODS : In this study , 182 patients with Alzheimer ( 125 women and 57 men ) were evaluated . - pubmed
Ground - glass opacity on chest computed tomography in a young , athletic man with coronavirus disease 2019 - related pneumonia without hypoxemia . - pubmed
The effect of oxytocin vaginal gel on vaginal atrophy in postmenopausal women : a randomized controlled trial . - pubmed
BACKGROUND : Around 90 % of postmenopausal women are suffering from vaginal atrophy . - pubmed
This study aimed to evaluate the effect of oxytocin vaginal gel on vaginal atrophy among postmenopausal women . - pubmed
METHODS : This was a randomized controlled trial that was conducted on 96 postmenopausal women who suffered from vaginal atrophy . - pubmed
After 8 weeks , 88.6 and 7.1 % of women in the oxytocin and placebo groups did not show the severe symptoms of vaginal atrophy ( p = 0.001 ) . - pubmed
The median patient age was 61 yr and median preoperative tumor size was 30 mm . - pubmed
Fingolimod reduces salivary infiltrates and increases salivary secretion in a murine Sjogren ' s model . - pubmed
We thus examined in an animal model of SjS the effects of Fingolimod ( FTY720 , Gilenya ) , which interferes with migration of lymphocytes to peripheral sites . - pubmed
Oral Fingolimod thus merits further consideration in the management of SjS in humans . - pubmed
Impact of SARS - CoV-2 Pandemic on " Stroke Code " Imaging Utilization and Yield . - pubmed
Increased Incidence of Giant Cell Arteritis After Introduction of a Live Varicella Zoster Virus Vaccine . - pubmed
Background : Varicella zoster virus ( VZV ) has been associated with giant cell arteritis ( GCA ) . - pubmed
The nutritional requirements of 43 strains of Haemophilus influenzae isolated from clinical and normal flora sources were investigated . - pubmed
Runt disease in suckling hybrid mice : substrain differences and litter seriation . - pubmed
Upon entry into the cytoplasm of irradiated chicken embryo cells in slide chamber cultures infected over a 2 - h period , yolk sac - grown virulent ( Breinl strain ) and attenuated ( E strain ) Rickettsia prowazeki underwent indistinguishable reproducible intracellular growth cycles . - pubmed
Frequency of ahaptoglobinaemia ( ahp ) in adult population ( on the base of investigation of 4000 cases ) was found 0.225 per cent , in children ( on the base of investigation of 119 children younger than 2 years ) 0.94 per cent . - pubmed
A 10 - year series of 100 patients with clinically undiagnosed prostatic adenocarcinoma is presented . - pubmed
In 50 per cent of these patients the tumor was well differentiated and the survival was normal , while the remainder of the patients had moderately to poorly differentiated tumors and survival rates significantly less than normal . - pubmed
The sera of 67 patients with thymomas-43 with myasthenia gravis ( thymoma(+ ) MG(+ ) ) and 24 without myasthenia gravis ( thymoma ( + ) MG ( - ) ) from 5 Dutch centers were examined with the indirect immunofluorescence test for the presence of antibodies reacting with skeletal muscle ( AMA ) , thyroid tissue , gastric parietal cells , adrenocortex and antinuclear antibodies ( ANA ) . - pubmed
The data were compared with those obtained in a group 83 MG patients in whom a thymoma was excluded by histological verification ( thymoma ( - ) MG ( + ) ) and with 1106 controls from the normal population . - pubmed
Patients with MG and without antimuscle antibodies have no thymomas : This rule is of practical value in the management of the MG patient . - pubmed
A total of 313 patients with childhood acute leukemia received a combination of vincristine ( 2 mg / m2 / week ) and prednisone ( 60 mg / m2 / day ) ; 86 % of 276 evaluable patients achieved a complete bone marrow remission in a median of 35 days . - pubmed
Between January 1 , 1971 and February 1 , 1974 , 31 patients have undergone laparotomy for staging of a malignant lymphoma , Hobgkin or not . - pubmed
Group A received ivermectin 0.1 mg / kg orally at a single dose , the cure rates were 100 % , 3.8 % and 50 % for ascaris , hookworm and trichuris , infections respectively : group B received ivermectin 0.2 mg / kg orally at a single dose , the corresponding cure rates were 95.5 % , 11.8 % and 76.5 % respectively ; group C received pyrantel pamoate 10 mg / kg orally at a single dose , the corresponding cure rates were 95.5 % , 29.6 % and 31.6 % respectively . - pubmed
Although the cure rates were very low for hookworm infection in both group A and B , however , a number of adult worms of Ancylostoma duodenale and Necator americanus were expelled aster medication ; It indicates that ivermectin has some effects on these two species of human hookworm . - pubmed
The current study traces the development of contractile cells in the nonmuscular segments of rat lung microvessels in hyperoxic pulmonary hypertension . - pubmed
Associated anti - epileptic therapy affected the CBZ L / D ratio , which was significantly reduced in patients on polytherapy as compared to patients on monotherapy . - pubmed
The study therefore suggests that routine monitoring of CBZ serum levels is extremely useful , especially in the paediatric age group , and in patients who require associated anti - epileptic medication . - pubmed
New strategies in antineoplastic therapy that have been applied during the last 5 years to children with malignant disease include the Goldic - Coldman hypothesis , new methods of drug delivery , reduction in toxicity with prolonged intravenous infusions , shortening of maintenance therapy and techniques to improve the compliance of adolescents and older children with prescribed therapy . - pubmed
These new concepts of chemotherapy in developmental pharmacology to treat cancers in children are reviewed . - pubmed
The 92 piglets were divided into the following 5 groups : swimmers with infection ( S - I ; n = 19 ) ; swimmers without infection ( S ; n = 19 ) ; control piglets with infection ( K - I ; n = 21 ) ; controls without infection , but direct ( K1 ; n = 16 ) or indirect contact ( K2 ; n = 17 ) with experimentally infected animals . - pubmed
The experimental or spontaneous infection ( direct or aerogenous infection ) with M. - pubmed
Contact urticaria from runner bean ( Phaseolus multiflorus ) . - pubmed
[ Human dirofilariasis in Italy : a new palpebral case with spontaneous healing in Abruzzo ] . - pubmed
One case of human palpebral dirofilariasis by Dirofilaria repens , in Abruzzo , is described . - pubmed
Antimicrobial MIC data were obtained for 96 strains of Staphylococcus haemolyticus and the following 11 antimicrobial agents : methicillin , gentamicin , rifampin , fusidic acid , ciprofloxacin , vancomycin , teicoplanin ; three experimental glycopeptides , MDL 62,873 , MDL 62,208 , and MDL 62,224 ; and an experimental lipoglycopeptide , ramoplanin . - pubmed
Recordings were made in normal sinus rhythm ( NSR ) ( 5 beats each in 8/8 patients ) , during ventricular tachycardia ( VT ) ( 38 beats with 7 morphologies in 3 patients ) and during premature ventricular contractions ( PVCs ) ( 20 beats with 8 morphologies in 6 patients ) . - pubmed
Intervals between the intrinsic deflection of the two ventricular electrograms ranged from 0 to 91 ms ( mean of 26 ms ) during NSR , from 13 to 141 ms ( mean of 66 ms ) during VT , and from 10 to 72 ms ( mean of 40 ms ) during PVCs and were reproducible within each patient for each type of rhythm . - pubmed
The use of protein preparations and fresh frozen plasma is believed essential in intensive plasmapheresis in patients with immunomediated disorders and DIC syndrome , respectively . - pubmed
Mice transgenic for a vasopressin - SV40 hybrid oncogene develop tumors of the endocrine pancreas and the anterior pituitary . - pubmed
A possible model for human multiple endocrine neoplasia type 1 . - pubmed
The possible relationship between the endocrine tumor syndrome found in the vasopressin - SV40 transgenic mice and familial human multiple endocrine neoplasia is discussed . - pubmed
[ Treatment of patients with stage I non - seminomatous testicular tumors with general orchiectomy ] . - pubmed
A group of 24 patients with non - seminomatous germ cell tumors of the testis in clinical stage I were followed in a prospective study in order to evaluate the strategy of " surveillance " consisting of regular check - up and administration of chemotherapy in the case of progression of the disease . - pubmed
A continuous cell line of chimpanzee lymphocytes producing an antibody specifically associated with non - A , non - B hepatitis ( NANB ) was established . - pubmed
Peripheral blood lymphocytes of a chimpanzee convalescent from experimental infection with NANB hepatitis were transformed in vitro by Epstein - Barr virus infection into lymphoblastoid cell lines . - pubmed
Supernatants of the cell cultures were screened by immunofluorescence for antibody activity against the liver tissue of a chimpanzee with NANB hepatitis . - pubmed
In addition , examinations of serial liver biopsy specimens obtained from 2 chimpanzees experimentally infected with NANB hepatitis demonstrated that the antibody reacted with the biopsies obtained during the preacute , acute , and chronic hepatitis , but not with those obtained before inoculation , early incubation period , or during convalescence . - pubmed
Immunoelectron microscopy revealed that the antibody reacted with the microtubular aggregates identical to those previously described in a patient and chimpanzees with NANB hepatitis . - pubmed
Ninety - eight patients died ( overall mortality 3.2 per cent ) and intraperitoneal sepsis was a related factor in twelve ( 0.4 per cent ) . - pubmed
A case of osteomyelitis due to Kingella kingae is presented to illustrate the insidious onset and indolent course typical of bone infections caused by this organism . - pubmed
Initial therapy with an aminopenicillin such as ampicillin in addition to antimicrobial drugs for Staphylococcus aureus should be effective in resolving bone and joint infections in children . - pubmed
Comparative developmental and phenotypic properties of altered hepatocyte foci and hepatic tumors in rats . - pubmed
Previous investigations in this laboratory have provided evidence that histochemically detectable altered hepatocyte foci and hepatic tumors appearing in rats given a single neonatal treatment with a low dose of carcinogen followed by chronic dietary phenobarbital administration are developmentally independent . - pubmed
The developmental and phenotypic properties of the hist(+)/morph(- ) foci , hist(+)/morph(+ ) foci , and hepatic tumors were compared in rats initiated once neonatally with different doses of diethylnitrosamine and promoted with dietary phenobarbital from weaning . - pubmed
Care study -- Clostridium difficile : enteric spread of infection . - pubmed
Wound pieces taken from 3 - 6 sites at a time during surgical treatment of the wound in 10 patients with thermal burns involving 25 - 50 % of the body surface area , were examined by electron - microscopic radioautography and bacteriologically . - pubmed
The burn wounds were found to contain not only live ( RNA - synthesizing ) bacteria but also replicating ( DNA - synthesizing ) bacteria , and to be heterogeneous in terms of bacterial seeding ( the largest numbers being present in the scab and the smallest , in the granulation tissue ) , but not of bacterial species ; these were represented in all layers by mixed populations ( Pseudomonas aeruginosa , pathogenic Staphylococcus , Proteus ) , although the deep layers contained more pathogenic and more virulent subpopulations than the more superficial ones . - pubmed
Healing of horizontal circumferential periodontal defects following regenerative surgery in beagle dogs . - pubmed
Regenerative surgery of dog teeth with reduced periodontal support was undertaken to determine : if new connective tissue attachment could be predictably attained back to the level of the cemento - enamel junction ; and to what extent the new attachment would be accompanied by bone regeneration , root resorption , and ankylosis . - pubmed
A morphometric analysis of the inflammatory infiltrate cells of the stroma and adjacent tissue of adenocarcinomas of the rectum was performed in 40 patients . - pubmed
Monteggia fracture - dislocations in children . - pubmed
Thirty - three Monteggia fracture - dislocations occurring in patients aged 2 to 15 years were reviewed . - pubmed
A mild hyperextension deformity at the elbow noted on follow - up of patients with anterior dislocation of the radial head seemed to support the theory that the injury is caused by hyperextension . - pubmed
A new classification of Monteggia fracture - dislocations in children is proposed . - pubmed
In short - term cultures of thymocytes from tetanus toxoid - immunized mice , the addition of 1 ng of toxoid generated the release of a soluble factor which was capable of enhancing the immune response to a heterologous immunogen . - pubmed
[ Production of stomach and pancreatic cancer in the guinea pig using methylnitroso - urea and methylnitroso - urethane ] . - pubmed
[ Changes in the diameter of some cell strains transformed by adenovirus and SV 40 virus , studied in vitro and in vivo ] . - pubmed
[ Contractility of the human uterus with a cesarean section scar ( author 's transl ) ] . - pubmed
[ Cataract extraction in patients with hypertension ] . - pubmed
Vaginal discharge and histological change of the ovary and the uterus in the rat . - pubmed
[ Treatment and chemoprevention of brucellar abortion in cattle with 4 - 4 ' , diaminodiazoaminobenzol ] . - pubmed
Evaluation of radiosensitivity in the cyclic phases of mouse fibrosarcoma cells in vitro . - pubmed
In the clinical study , four glioma patients were treated by intravenous administration of Cisplatin 10 mg / sqm for 5 days q 4 weekly . - pubmed
Three patient with intracranial embryonal carcinoma were treated by cisplatin . - pubmed
In a study of 30 consecutive patients with constrictive pericarditis diagnosed by clinical , radiological , and echocardiographic criteria 21 ( 70 % ) were found to have pulsatile hepatomegaly . - pubmed
Thus this poorly appreciated clinical finding appears to be present in a high proportion of patients with constrictive pericarditis . - pubmed
[ Power in the periphery of several aspheric eyeglasses for aphakic patients ] . - pubmed
[ Quantitative content of Bacteroides in normal human intestines and in dysbacteriosis ] . - pubmed
In the fed state , obese rats showed more rapid clearance of the label from the bloodstream and , in both fed and fasted states , greater uptake into retroperitoneal and parametrical fat pads than lean rats . - pubmed
Obese rats showed proportionally less uptake into heart and liver . - pubmed
Comparison of highly basic cyanogen bromide peptides from strains of southern bean mosaic virus . - pubmed
Forty - nine patients ( 29.3 % ) developed 83 postoperative complications . - pubmed
OBJECTIVE : This report reviews the case of a missed cervical spine fracture in a patient presenting for chiropractic manipulative therapy . - pubmed
CLINICAL FEATURES : A 65 - yr - old woman presented to a chiropractic office for examination and treatment of cervical spine injuries suffered in a deceleration type motor vehicle accident . - pubmed
This case demonstrates that chiropractors should be extremely cautious in initiating manipulative therapy in those patients having sustained previous cervical spine trauma and who have had prior X - rays that have been reported normal . - pubmed
Each animal was chronically instrumented with an electromagnetic flow probe on the ascending aorta , a strain gauge pressure transducer implanted in the apex of the left ventricle ( LV ) , and electrocardiogram leads anchored to the chest wall and LV . - pubmed
Enhanced gamma - aminobutyric acid - mediated responses in nucleus tractus solitarius of hypertensive rats . - pubmed
In both groups of hypertensive rats the pressor response to injection into the nucleus tractus solitarius of the GABA uptake blocking drug nipecotic acid was significantly greater compared with control rats ( P & lt ; .01 in each model ) . - pubmed
The controversy extends to the nonobese diabetic ( NOD ) mouse that develops disease similar to human insulin - dependent diabetes mellitus . - pubmed
Autoreactive T cells are present , functional , and can transfer diabetes to appropriate NOD - recipient mice . - pubmed
OBJECTIVE : This study investigated these delay periods and the compliance with therapy in children with tuberculosis . - pubmed
DESIGN : During the study period there were 49 children with probable and 123 with confirmed pulmonary tuberculosis ( WHO criteria ) . - pubmed
Subjects with cutaneous facial photodamage were randomised to treatment with tretinoin ( 62 ) or vehicle ( 63 ) cream . - pubmed
Dietary vitamin B12 deficiency in a patient with multiple sclerosis . - pubmed
The authors present a case of dietary vitamin B12 deficiency in a patient with multiple sclerosis . - pubmed
A simple schemata for evaluating patients for vitamin B12 deficiency is included as a clinical aid for physicians . - pubmed
Effect of maternal paraquat administration on the fetal ductus arteriosus in the rat . - pubmed
The ductus arteriosus ( DA ) in the fetal rat was calibrated using a whole - body freezing method , 3 hr after maternal treatment with paraquat at a dose of 25 mg / kg of body weight on days 19 - 21 of gestation . - pubmed
Seventy - one Escherichia coli strains isolated from diarrhoeic weaned rabbits from different areas of France were tested for the presence of DNA sequences specific for the EPEC , EHEC , DAEC and EAggEC strains and 16 of them were tested for pathogenicity in animal experiments . - pubmed
Clinically comparable , randomized sites of 8 patients with progressive adult periodontitis were treated 4 times in intervals of approximately 4 months . - pubmed
Analysis of Dolichos biflorus - reactive axons revealed that these axons coursed randomly , with no evidence of their selective fasciculation , within the olfactory nerve . - pubmed
Oral administration of nitrendipine ( 5 or 10 mg , 3 h before induction of anaesthesia ) was able to attenuate the hypertensive response to tracheal intubation in ASA 1 patients under light anaesthesia . - pubmed
We propose this pharmacological technique with supplementary doses of opioids and/or benzodiazepines for the management of patients with hypertension or coronary artery disease . - pubmed
This suggests use of the CMV promoter for gene therapy targeted at macrophages , as , for example , in the treatment of lysosomal storage disorders such as Gaucher disease . - pubmed
METHODS : Serum samples were obtained at 7 to 18 weeks of gestation from 58 women whose fetuses were known to be affected by Down ' s syndrome , 32 whose fetuses were affected by trisomy 18 , and 438 whose fetuses were normal , and the samples were analyzed for each marker . - pubmed
Regional chamber stiffness and myocardial stiffness were assessed using the end - diastolic pressure - length relationship which was modified by stepwise infusion and withdrawal of 200 mL of the animals ' own blood during baseline , 45 min low flow ischemia ( systolic bulge ) , and 60 min after the onset of reperfusion . - pubmed
Evaluation of the monitoring of papular dermatitis lesions in slaughtered swine to assess sarcoptic mite infestation . - pubmed
We investigated the association between the presence of papular dermatitis and sarcoptic mite infestation in pigs slaughtered in southern Minnesota . - pubmed
Following dehairing , a sample of 30 pigs from each of 50 herds was inspected for papular dermatitis lesions . - pubmed
Herd infestation with sarcoptic mange was determined by recovery of mites from ear scrapings of slaughtered pigs and also by survey of producer opinion . - pubmed
Generalized lesions occurred in 36.7 % of pigs from herds confirmed to be infested , compared with 0.4 % of pigs in herds confirmed free from mange . - pubmed
Our date indicate that monitoring of dermatitis lesions in slaughtered pigs might be a useful test for sarcoptic mange in the Midwest , USA . - pubmed
In this study , a modified version of ASEPSIS ( a wound scoring system ) has been prospectively evaluated in 1000 patients undergoing cardiac surgery . - pubmed
Twenty - one patients ( 2.1 % ) had an infected sternal wound . - pubmed
Developmental toxicity of inhaled N - methylformamide in the rat . - pubmed
The developmental toxicity of N - methylformamide ( MMF ) , an industrial chemical intermediate used in the production of agrichemicals , was examined in pregnant rats . - pubmed
Maternal toxicity was evident in dams exposed to 50 or 150 ppm ; one dam exposed to 150 ppm died on Day 14 G ( considered to be treatment - related ) and dams in the 50 and 150 ppm groups exhibited concentration - related clinical findings . - pubmed
Phase II trial of intravenous endotoxin in patients with colorectal and non - small cell lung cancer . - pubmed
We report the immunological and clinical results of a phase II trial with intravenously administered highly purified endotoxin ( Salmonella abortus equi ) in patients with advanced cancer . - pubmed
15 patients with non - small cell lung cancer and 27 with colorectal cancer were entered into the study . - pubmed
Divergent selection for body weight and yolk precursor in Coturnix coturnix japonica . - pubmed
[ Acquisition of ability to metastasize by spontaneous tumors under the effect of metastazin 1 in transgenic animals ] . - pubmed
[ Nootropil in the treatment of disorders of the higher mental functions in patients with an ischemic stroke ] . - pubmed
47 patients with acute ischemic stroke were treated with nootropil ( pyracetam , UCB , Belgium ) from the first day of the disease ( 12 g , intravenously , by drops during 2 weeks , then 4.8 g , per os ) on the background of basic therapy . - pubmed
There was observed more pronounced positive dynamics of functions of damaged hemisphere in patients with localisation of ischemic focus in left hemisphere . - pubmed
The conclusion was made that nootropil can be prescribed for the patients with hemispheric ischemic stroke and especially for the patients with alterations of cerebral circulation in system of internal carotid artery including such disturbances on the background of insufficiency of circulation in vertebrobasilar system . - pubmed
Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy : a randomized control trial . - pubmed
BACKGROUND : The aim of the current prospective , randomized control study was to investigate the effect of dietary omega-3 polyunsaturated fatty acids plus vitamin E on the immune status and survival of well - nourished and malnourished patients with generalized malignancy . - pubmed
METHODS : Sixty patients with generalized solid tumors were randomized to receive dietary supplementation with either fish oil ( 18 g of omega-3 polyunsaturated fatty acids , PUFA ) or placebo daily until death . - pubmed
CONCLUSIONS : Malnutrition appears to be an important predictor of survival for patients with end stage malignant disease . - pubmed
Omega-3 polyunsaturated fatty acids had a significant immunomodulating effect and seemed to prolong the survival of malnourished patients with generalized malignancy . - pubmed
Patients were stratified by Karnofsky performance status and presence or absence of liver metastases . - pubmed
To evaluate the contribution of reactive nitrogen species to inflammation by asbestos , Fischer 344 rats were exposed to crocidolite or chrysotile asbestos by inhalation to determine whether increases occurred in nitric oxide ( NO . ) - pubmed
BACKGROUND AND OBJECTIVE : Two - dimensional polyacrylamide gel electrophoresis ( 2 - D PAGE ) is a new method which can be used to study cryoprecipitates from the sera of cryoglobulinemic patients . - pubmed
DESIGN AND METHODS : Sixty consecutive patients affected by cryoglobulinemic syndrome with mixed cryoglobulins were included in the study . - pubmed
All patients were evaluated for cutaneous , articular , hepatic , renal and nervous involvement . - pubmed
However , RA resistance arises during RA treatment of APL patients . - pubmed
Antitumor activity of ZD1694 ( tomudex ) against human head and neck cancer in nude mouse models : role of dosing schedule and plasma thymidine . - pubmed
Among 62 consecutive patients with their first lacunar stroke and 202 normal controls , we found that hypertension ( p & lt ; 0.001 ) , smoking ( p = 0.001 ) , and aortic arch atheroma ( p = 0.006 ) were independently associated with an increased risk of lacunar stroke . - pubmed
METHODS : The clinical and epidemiological features of 102 children with extra - pulmonary tuberculosis , diagnosed between 1982 and 1998 at P & amp ; A Kyriakou Children 's Hospital were reviewed . - pubmed
The source of infection was disclosed in 48 patients . - pubmed
Miliary tuberculosis developed in infants , lymphadenitis and meningitis in preschool children , and pleural effusion and skeletal tuberculosis in older children . - pubmed
A case report of the use of magnesium sulphate during anaesthesia in a patient who had adrenalectomy for phaeochromocytoma . - pubmed
INTRODUCTION : Patients with phaeochromocytoma have haemodynamic instability during adrenalectomy . - pubmed
OUTCOME : The patient had to be given phentolamine and sodium nitroprusside to control the severe hypertension . - pubmed
Following the operation , the patient suffered from transient right abducens nerve palsy , which persisted for 3 months . - pubmed
Enterohemorrhagic Escherichia coli ( EHEC ) O157 : H7 causes serious diarrhea and hemolytic uremic syndrome in humans . - pubmed
Body composition changes in patients with anorexia nervosa after complete weight recovery . - pubmed
SUBJECTS : : Ten female patients with anorexia nervosa ( age at baseline : 19.7+/-5.8 y ) were studied both when undernourished ( body mass index , BMI 14.8+/-1.3 kg/ m(2 ) ) and after the achievement of a BMI & gt;18.5 kg / m(2 ) . - pubmed
Mapping studies in patients with drug - refractory paroxysmal atrial fibrillation identified potentials from the ostia of pulmonary veins as a main source of triggers that initiate atrial fibrillation . - pubmed
Correlation of blood - glucose control with oxidative metabolites in plasma and vitreous body of diabetic patients . - pubmed
This study investigated patients with diabetic retinopathy for evidence of oxidative metabolites in plasma and the vitreous body , correlating these values with blood - glucose control . - pubmed
METHODS : The study comprised 136 patients suffering from proliferative diabetic retinopathy . - pubmed
[ Defects of the low urinary tract as a cause of recurrent urinary tract infection in girls ] . - pubmed
462 girls aged 1 month--15 years with recurrent urinary tract infection were diagnosed in the Outpatient Clinic of Mother and Child Institute during 1985 - 1992 and 1999 - 2000 years period . - pubmed
We present a detailed case report of a 25 - year - old man with PVNS of the hip . - pubmed
Silent lupus nephritis ( SLN ) was investigated in 42 renal asymptomatic patients and compared with 49 untreated patients with overt lupus nephropathy ( OLN ) . - pubmed
Forty - one out of the 42 ( 97.6 % ) patients had SLN according to histopathological findings . - pubmed
We conclude that , in our series , SLN was highly prevalent in renal asymptomatic patients with otherwise systemic lupus erythematosus . - pubmed
[ Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancer ] . - pubmed
[ Blood and cerebrospinal fluid findings in molimina crurum nocturna ( including restless legs ) ] . - pubmed
Inhaled corticosteroids with long acting beta 2 - mimetics have become the mainstay of therapy for patients with asthma . - pubmed
Are anticonvulsants a satisfactory alternative to opiate analgesia in patients experiencing pain with Guillain - Barre syndrome ? - pubmed
We report a patient being followed for chronic renal insufficiency by renal ultrasound in whom a renal mass was detected . - pubmed
Tacrolimus ointment is safe and effective for short- and long - term treatment of atopic dermatitis ( AD ) in pediatric and adult patients . - pubmed
CASE REPORT : A 51 - year - old patient undergoing surgery for a right postcentral glioma was first submitted to phase reversal of somatosensory potentials for intraoperative localization of the central sulcus . - pubmed
[ Optic nerve damage in multiple sclerosis patients ] . - pubmed
PURPOSE : The aim of the work was to catch the type of damage of optic nerve in the group of patients with multiple sclerosis . - pubmed
MATERIAL AND METHODS : The examinations were held on 77 eyes of 40 patients with multiple sclerosis . - pubmed
Among them 11 patients had previous optic neuritis , 29 have not problems with vision . - pubmed
CONCLUSIONS : Psychophysical tests enable early diagnosis and monitoring of optic nerve damage in multiple sclerosis patients . - pubmed
The authors report the results of a phase IIa immunotherapy trial of AN1792(QS-21 ) in patients with mild to moderate Alzheimer disease ( AD ) that was interrupted because of meningoencephalitis in 6 % of immunized patients . - pubmed
METHODS : This randomized , multicenter , placebo - controlled , double - blind trial of IM AN1792 225 microg plus the adjuvant QS-21 50 microg ( 300 patients ) and saline ( 72 patients ) included patients aged 50 to 85 years with probable AD , Mini - Mental State Examination ( MMSE ) 15 to 26 . - pubmed
RESULTS : Following reports of meningoencephalitis ( overall 18/300 [ 6 % ] ) , immunization was stopped after one ( 2 patients ) , two ( 274 patients ) , or three ( 24 patients ) injections . - pubmed
Methicillin - resistant Staphylocosis aureus ( MRSA ) is an emerging infection in patients with cystic fibrosis ( CF ) . - pubmed
Experimental autoimmune uveitis ( EAU ) can be induced in susceptible mice by immunization with retinal antigens . - pubmed
Giving that a large number of transgenic and KO mice are available in B6 background , an improved uveitis model in B6 mouse should assist the determination of pathogenesis of disease and identify molecules that can be targeted by new therapies . - pubmed
Comparison of indices of vitamin A status in children with chronic liver disease . - pubmed
The most accurate way to assess vitamin A status in children who have cholestasis is unknown . - pubmed
Children with chronic cholestatic liver disease ( n = 23 ) and noncholestatic liver disease ( n = 10 ) were studied . - pubmed
Ten cholestatic patients were identified as vitamin A - deficient based on the relative dose response ( RDR ) . - pubmed
In conclusion , vitamin A deficiency is relatively common in children who have chronic cholestatic liver disease . - pubmed
After characterization of the natural spread of necrosis - inducing Bean yellow mosaic potyvirus ( family Potyviridae , genus Potyvirus , BYMV(N ) ) , nonpersistently transmitted from clover , Trifolium repens L. , to an adjacent field of snap bean , Phaseolus vulgaris L. , in western Oregon , we established a study site enabling us to investigate the virus reservoir , to observe en masse transmission of BYMV(N ) to bean plants , and to identify aphid species associated with virus spread . - pubmed
Percutaneous radiofrequency ablation of renal tumors : midterm results in 16 patients . - pubmed
PURPOSE : To evaluate the outcome of 16 patients after percutaneous radiofrequency ablation of renal tumors . - pubmed
Only one patient had evidence of local recurrent tumor . - pubmed
Human Papillomavirus ( HPV ) vaccines will likely have an impact as a preventive strategy for cervical cancer . - pubmed
Screening for precancerous lesions can not be discontinued because vaccination will not protect against HPV types not included in the first generation of vaccines . - pubmed
Moreover , protection for the target types , 16 and 18 , which are responsible for most cases of cervical precancerous lesions and cancer , and 6 and 11 , which are responsible for a substantial proportion of low - grade lesions , can not be expected to be absolute , and the likely implementation of HPV vaccination in young women will not impact older groups initially . - pubmed
Cervical cancer control programs will need to be re - evaluated because the addition of HPV vaccination will make the existing approach of high - frequency screening by cytology too costly and inefficient for most public health budgets . - pubmed
Another advantage of using HPV testing as a primary screening tool is the opportunity to create infection registries that can link test results from the same women over time , thus allowing an efficient and low - cost strategy to monitor long - term protection among vaccinated women . - pubmed
BACKGROUND : Endoscopic treatment of intractable chronic anterior and lateral exertional compartment syndromes of the lower leg in athletes is reported anecdotically only in six patients . - pubmed
No complications were seen following endoscopic anterior and lateral compartment decompression , while two patients following deep posterior compartment release underwent open revision surgery due to hemorrhage . - pubmed
There were no postoperative complications due to vascular injuries in all further patients who were operated without tourniquet . - pubmed
METHODS : We studied 12 subjects with pulmonary alveolar proteinosis , 61 healthy control subjects , and 12 control subjects with either cystic fibrosis or end - stage liver disease . - pubmed
The accumulation of complex hepatitis B virus ( HBV ) variants with internal in - frame deletions in the C gene in immunosuppressed renal transplant recipients is associated with a severe course of the infection leading to end - stage liver disease ( ESLD ) . - pubmed
There were no differences in remissions , time to remission , relapse rate , or time to relapse between daily- and alternate - day - treated patients . - pubmed
At follow up , patients with an episode of ARF had higher serum creatinine than those without ARF . - pubmed
Four patients progressed to ESRD . - pubmed
These patients were less likely to have responded to steroids and more likely to have FSGS on repeat renal biopsy . - pubmed
ARF occurs in a significant number of adult MCD patients and may leave residual renal dysfunction . - pubmed
Few patients progress to ESRD . - pubmed
URINE CHLORIDE CONCENTRATION IN PATIENTS WITH CUSHING ' S SYNDROME . - pubmed
A clinical epidemiological study in 2169 patients with vertigo . - pubmed
METHODS : Retrospective study on 2169 patients with vertigo ( male 883 , female 1286 , 7 - 90 years old ) of the past 20 years . - pubmed
Peripheral , central , and unclassified vertigo took up 33.8 , 17.2 and 26.8 % of patients , respectively , while vertigo of unknown origin was around 22.2 % . - pubmed
Spontaneous urinary calcium oxalate crystallization in hypercalciuric children . - pubmed
We assessed the associations between spontaneous CaOx crystallization based on the Bonn Risk Index ( BRI ) , urinary pH , calciuria , oxaluria , and citraturia in 140 Caucasian patients with hypercalciuria , aged 4 - 17 years , and compared the findings with those in 210 normocalciuric controls . - pubmed
Of the 140 hypercalciuric patients , 58 had renal stones , and 82 had recurrent erythrocyturia , renal colic , or urinary obstructive symptoms - but without stones . - pubmed
Determination of the BRI in children with hypercalciuria may improve the risk assessment of kidney stones . - pubmed
We excluded patients presenting with an acute ST - elevation myocardial infarction ( MI ) within & lt ; or = 24 hours , hemodynamic instability / shock , thrombolytic therapy within & lt ; or = 7 days , or renal insufficiency . - pubmed
Ozone ameliorates methotrexate - induced intestinal injury in rats . - pubmed
Thus , this study was designed to investigate the efficacy of ozone therapy in the prevention of Mtx - induced intestinal injury in rats . - pubmed
[ The use of atorvastatin in patients with rheumatoid arthritis with hyperlipidemia ] . - pubmed
MATERIAL : Patients with RA ( n=50 ) were divided into 2 groups . - pubmed
CONCLUSION : The data obtained allow to recommend the use of atorvastatin for long term management of hyperlipidemia in patients with RA . - pubmed
IVUS detected CAV in 17 of 30 patients ( 57 % ) and in 41 of 110 coronary segments ( 37 % ) . - pubmed
We found only 14 children reported to have bilateral vocal fold paralysis associated with CMT , and only 1 of these cases was associated with CMT type 1 . - pubmed
Cell culture processes offer an attractive alternative to conventional chicken egg - based influenza vaccine production methods . - pubmed
Production in serum - free suspension of HEK-293 cultures resulted in high titers of infectious influenza viruses for different subtypes and variants including A / H1 , A / H3 and B strains . - pubmed
BACKGROUND : Surgical excision can cure most patients with malignant melanoma of the skin . - pubmed
METHODS : Data from 2487 patients with malignant melanoma and primary treatment between 1978 and 1997 at the Department of Surgery or the Department of Dermatology , University Hospital Erlangen , Germany , were prospectively collected in the Melanoma Registry of the University Hospital Erlangen . - pubmed
RESULTS : Overall survival was found to be significantly worse in older patients , men , melanoma of the head or trunk , and melanoma with high pT and pN categories . - pubmed
In 523 patients , relapse from malignant melanoma was observed after a median of 24 months . - pubmed
Among patients with recurrences , young age and low pT and pN categories proved to be independent factors that prolonged the disease - free interval . - pubmed
Despite wide distribution of this virus , designated Calbertado virus , strains demonstrate a high degree of nonstructural protein 5 nucleotide ( & gt ; 90 % ) and amino acid ( & gt ; 97 % ) identity . - pubmed
The ecology and geographic range of Calbertado virus warrants further study because it may potentially influence transmission of mosquito - borne flaviviruses , including important human pathogens such as West Nile and Saint Louis encephalitis viruses . - pubmed
Despite advances in treatment , the prognosis of a patient with amyloidosis is still poor and depends upon the underlying disease , and the type and degree of dysfunction of the involved organs . - pubmed
Although the roles of mast cells ( MCs ) are essential in many inflammatory and fibrotic diseases , their role in Trypanosoma cruzi - induced cardiomyopathy is unexplored . - pubmed
Although these data show that MCs are important in controlling acute infection , we observed MC apoptosis in the cardiac tissue and peritoneal cavity of untreated mice . - pubmed
METHODS : The 32 patients with Type 2 diabetes and 15 healthy controls were enrolled into the study . - pubmed
All three strains produced a rhamnolipid that differs in structure from Pseudomonas aeruginosa rhamnolipids and exhibits excellent surfactant properties . - pubmed
Proteomic analysis of urine in medication - overuse headache patients : possible relation with renal damages . - pubmed
Various epidemiologic investigations proved that different drug types could cause nephrotoxicity , particularly in chronic patients . - pubmed
The aim of the present work was to analyze , by a proteomic approach , the urinary protein profiles of MOH patients focusing on daily use of NSAIDs , mixtures and triptans that could reasonably be related to potential renal damage . - pubmed
In conclusion , this preliminary proteomic study allowed us to define the urinary protein pattern of MOH patients that is related to the abused drug . - pubmed
According with the obtained results , we believe that the risk of nephrotoxicity should be considered particularly in MOH patients who abuse of NSAIDs . - pubmed
The type strain is A8036(T ) ( = DSM 45508(T ) = KCTC 19868(T ) ) . - pubmed
Patients with neuromuscular disorders are often complicated by progressive scoliosis . - pubmed
We must pay attention to spinal deformity in patients with Duchenne muscular dystrophy , especially after they lose the ability to walk because spinal deformity frequently develops . - pubmed
MATERIALS AND METHODS : Urothelial bladder carcinoma patients ( n=38 , including 31 men and 7 women ) and healthy controls ( n=25 , including 20 men and 5 women ) were included in the study . - pubmed
gammadelta T cells are also able to respond to local inflammation and consequently regulate the pathogenesis of autoimmune disorders and development of tumors in mice and humans . - pubmed
Among the 30 patients , 21 patients survived ( 70 % ) and 9 patients with community - acquired pneumonia ( CAP ) died ( 30 % ) . - pubmed
The 21 surviving patients included 17 patients with acute respiratory distress secondary to CAP and 4 patients with asthmatic crisis upon admission to the ICU . - pubmed
After admission , all patients progressed to sepsis and showed an increase in blood glucose . - pubmed
It is therefore important to measure continuously glucose concentrations , as well as the numbers of neutrophils and lymphocytes in critically ill patients with hyperglycemia . - pubmed
Ciguatera toxicity is a poisoning from consuming reef fish that had fed on dinoflagellates such as Gambierdiscus toxicus found along coral reefs . - pubmed
Its abnormal expression may be involved in the oncogenesis of human malignancies such as lung cancer . - pubmed
However , even though intrathecally delivered synthetic omega - conotoxin MVIIA from Conus magnus ( ziconotide [ Prialt ] ) has been approved for the treatment of chronic pain in humans , its mode of delivery and narrow therapeutic window have limited its usefulness . - pubmed
In vivo efficacy in rat models of inflammatory and neuropathic pain was demonstrated by a representative compound from this series . - pubmed
The study objective was to determine the prevalence of vitamin D deficiency , risk factors for its presence , and potential association with clinically relevant outcomes in critically ill children . - pubmed
Data and biological samples from 326 critically ill children up to 17 years of age were available for analysis . - pubmed
CONCLUSIONS : This study provides evidence that vitamin D deficiency is both common among critically ill children and associated with greater severity of critical illness . - pubmed
Recent studies have shown that downregulation of the microRNA miR-124 occurs in several types of human cancer , suggesting a tumor suppressive function of miR-124 . - pubmed
Application of stent placement or nasojejunal feeding tube placement in patients with malignant gastric outlet obstruction : a retrospective series of 38 cases . - pubmed
Patients treated for primary adrenal insufficiency ( PAI ) are at risk of steroid over - replacement , which may affect their skeleton . - pubmed
Lumbar spine osteoporosis and osteopenia were found in 12 and 31 patients , respectively , whereas in femoral neck : in 5 and 33 individuals . - pubmed
METHODS : We analyzed 150 consecutive patients who underwent elective gastric cancer surgery at the Shiga University of Medical Science Hospital ( Shiga , Japan ) from 1997 to 2009 ; of these , most surgeries ( n = 100 ) were performed 2008 onwards . - pubmed
The patient characteristics and surgery - related factors between two groups ( with and without infection ) were compared by the paired t - test and chi(2 ) test , including preoperative ADN levels , postoperative day 1 ADN levels , and ADN ratio ( postoperative ADN levels / preoperative ADN levels ) as baseline factors . - pubmed
RESULTS : Sixty patients ( 40 % ) experienced postoperative infections . - pubmed
Among the historical control group , the main causes of graft failure were patient deaths ( 68 % ) , which were mostly caused by liver diseases . - pubmed
The results shows that miRNA profile changes in HIV-1 seropositive individuals , and the 56 differentially expressed miRNAs may play important role during HIV infection . - pubmed
NSCs have been demonstrated to be very useful in grafts into the mammalian central nervous system to investigate the exploitation of NSC for the therapy of neurodegenerative disorders in animal models of neurodegenerative diseases . - pubmed
Reply to Errera and Campbell : No , low salinity shock does not increase brevetoxins in Karenia brevis . - pubmed
Effectiveness of Laminaria jam enriched with chromium has been investigated in ambulatory patients with metabolic syndrome . - pubmed
Differential effects of opioid - related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain . - pubmed
RATIONALE : Carrageenan - induced hyperalgesia is a widely used pain model in rodents . - pubmed
However , characteristics of carrageenan - induced hyperalgesia and effects of analgesic drugs under these conditions are unknown in nonhuman primates . - pubmed
RESULTS : Tail injection of carrageenan produced long - lasting thermal hyperalgesia in monkeys . - pubmed
The opioid - related ligands displayed differential pharmacological properties in regulating hyperalgesia and acute nociception in the same subjects . - pubmed
OBJECTIVE : To examine pain and biopsychosocial correlates over time for women with persistent postsurgical pain after surgery for endometriosis . - pubmed
METHODS : Cross - sectional study of women who underwent any endometriosis surgery between 2003 and 2006 . - pubmed
Following surgery , patients completed validated questionnaires ( Short - Form McGill Pain Questionnaire , 12 - item Short - Form Health Survey , Beck Depression Inventory , Coping Strategies Questionnaire catastrophizing subscale ) . - pubmed
Cystic fibrosis ( CF ) patients are at high risk of colonization of the airways by a number of fungi , including the emerging opportunistic fungus Geosmithia argillacea . - pubmed
Diffusion - weighted magnetic resonance imaging to evaluate microvascular density after transarterial embolization ablation in a rabbit VX2 liver tumor model . - pubmed
This information allows clinicians to better predict and manage communication impairment in children with cerebral palsy . - pubmed
Exploring the relationship between preferences for high fat foods and efficacy of the ketogenic and modified Atkins diets among children with seizure disorders . - pubmed
PURPOSE : Previous research has indicated that children with seizures may prefer high fat foods - a preference compatible with ketogenic and modified Atkins dietary therapies . - pubmed
Toward a comparative retrospective analysis of rat and rabbit developmental toxicity studies for pharmaceutical compounds . - pubmed
Genetic characterization of Vibrio vulnificus strains isolated from oyster samples in Mexico . - pubmed
Vibrio vulnificus strains were isolated from oysters that were collected at the main seafood market in Mexico City . - pubmed
An Erb 's Engram is a common debility that develops in recovering children with Erb ' s palsy . - pubmed
The purpose of this study was to investigate the effect of kinesiotaping over the deltoid and the forearm on the development of proper upper extremity function in children recovering from Erb ' s palsy . - pubmed
Thirty patients with Erb ' s palsy participated for 3 months in this study and were equally divided into two groups ; control group A and study group B. - pubmed
A posterior fossa intradiploic epidermoid cyst was removed from the calvarium of an otherwise healthy 34 - year - old woman after work up for dizziness and blurry vision . - pubmed
Although this would appear to affect a small number of patients , the impact of these changes are broad , leading to an increased use of advanced imaging , a debate around the management of patients previously diagnosed with smouldering myeloma , changed terminology and clinical trial design and an extension of the use of biomarkers . - pubmed
We sought to define trends for IMV in the United States and assess for disease - specific variation for 3 common causes of respiratory failure : pneumonia , heart failure ( HF ) , and chronic obstructive pulmonary disease ( COPD ) . - pubmed
METHODS : We calculated national estimates for utilization of nonsurgical IMV cases from the Nationwide Inpatient Sample from 1993 to 2009 and compared trends for COPD , HF , and pneumonia . - pubmed
CLINICAL CASE : A 17 - year - old patient with a progressively growing tumour in the right inguinoscrotal region . - pubmed
Effect of Chinese herbal medicines for nourishing yin , supplementing qi , and activating blood on reproductive endocrine activity and immune functions in patients with primary Sjogren ' s syndrome . - pubmed
OBJECTIVE : To investigate the effect of Chinese herbal medicines for nourishing yin , supplementing qi , and activating blood on the reproductive endocrine - immune network and its mechanisms in patients with primary Sjogren ' s syndrome ( pSS ) . - pubmed
METHODS : Seventy pSS patients were randomly assigned to two groups using a randomized digital table : the integrative therapy group ( 36 cases ) and the control group ( 34 cases ) . - pubmed
Chinese herbal medicines for nourishing yin , supplementing qi , and activating blood combined with Western medicine could improve the therapeutic effect by regulating the reproductive endocrine - immune network in pSS patients . - pubmed
Incidence and predictors of interstitial lung disease ( ILD ) in Thai patients with early systemic sclerosis : Inception cohort study . - pubmed
RESULTS : One hundred and thirteen patients ( 66 females and 89 diffuse cutaneous SSc [ dcSSc ] ) with a mean + - SD age of 53.4 + - 8.4 years and mean disease duration of 12.9 + - 10.3 months at cohort entry were enrolled . - pubmed
At enrollment , patients with dcSSc had a higher prevalence of ILD ( 78.7 % vs. 45.8 % , p = 0.002 ) , and a higher total HRCT score ( 10.3 + - 9.5 vs. 4.4 + - 5.6 , p = 0.001 ) compared with limited cutaneous SSc ( lcSSc ) . - pubmed
Efficacy of Probiotic Escherichia coli Nissle 1917 in Patients with Irritable Bowel Syndrome : a Double Blind Placebo - controlled Randomized Trial . - pubmed
139 confirmed IBS patients were included into the study , and were given probiotic E.coli Nissle 1917 for 6 weeks . - pubmed
49(35.3 % ) of the patients were diarrhea - predominant . - pubmed
Patients with constipation - predominant IBS showed no response to the probiotic ; while patients with diarrhea - constipation mixed IBS showed unfavorable response to the probiotic in the need for strain to pass a motion compared to the placebo ( p=0.03 and 0.02 at weeks 4 and 6 , respectively ) . - pubmed
CONCLUSION : probiotic therapy with E.coli Nissle 1917 was not able to induce significant improvement in the symptoms of patients with non - categorized IBS . - pubmed
The effect of D - galactosamine on lean and steatotic rat hepatocytes in primary culture . - pubmed
The aim of our work was to compare the effect of D - galactosamine ( GalN ) on primary cultures of lean and steatotic rat hepatocytes isolated from intact and fatty liver , respectively . - pubmed
Some reported effects of SPA pretreatment on septic shock in mouse models but there is no study which reports the role of SPA pretreatment on the infected incision . - pubmed
The bacterial suspension was gradually dripped and embrocated onto the incision surface to make the wound infection model . - pubmed
Before making the wound infection model for 48 hours and 24 hours , mice were retreated with SPA via intraperitoneal injection . - pubmed
RESULTS : A 1 - mL bacterial suspension can be utilized to make the wound infection model of BALB / c mouse lower limb . - pubmed
SPA pretreatment can reduce the inflammatory reactions in wound methicillin - resistant Staphylococcus aureus infection mouse model and the best pretreatment dose is 1 mg / kg . - pubmed
A 1 - mg / kg SPA pretreatment can also reduce the inflammatory reactions in wound various bacterial infection mouse models . - pubmed
CONCLUSION : SPA pretreatment can effectively decrease the infected severity of a wound infected by various bacteria in a BALB / c mouse model . - pubmed
Metabonomic profiles delineate potential role of glutamate - glutamine cycle in db / db mice with diabetes - associated cognitive decline . - pubmed
In this study , ( 1 ) H nuclear magnetic resonance - based metabonomics and immunohistochemistry was used to explore key metabolic alterations in hippocampus of type 2 diabetic db / db mice with cognition decline in order to advance understanding of mechanisms underlying the pathogenesis of the disease . - pubmed
Several tricarboxylic acid cycle intermediates including succinate and citrate were reduced in hippocampus of db / db mice with cognition decline . - pubmed
CONCLUSIONS : Our results suggest that the development of diabetes - associated cognition decline in db / db mice is most likely implicated in a reduction in energy metabolism and a disturbance of glutamate - glutamine shuttling between neurons and astrocytes in hippocampus . - pubmed
CONCLUSION : Early results of a large series of a modern TAA system demonstrate improvement in patient satisfaction , quality of life , activity , and pain for patients with end - stage ankle arthritis . - pubmed
PURPOSE OF REVIEW : The Gleason grading system provides important information for guiding prostate cancer patients ' management and prognostication . - pubmed
Predictors of survival in patients who underwent video - assisted thoracic surgery talc pleurodesis for malignant pleural effusion . - pubmed
BACKGROUND : Patients with malignant pleural effusion have a limited life expectancy . - pubmed
METHODS : We examined the medical records of all consecutive patients with malignant pleural effusion who underwent VATS talc pleurodesis from 2006 to 2008 at the Samsung Medical Center . - pubmed
RESULTS : During the study period , 91 patients underwent VATS talc pleurodesis to treat malignant pleural effusion . - pubmed
The postoperative respiratory complication rate was 11 % ( 10 patients ) , and included pneumonia ( 9 ) and acute respiratory distress syndrome ( 4 ) . - pubmed
When PC3 cells were injected into proximal tibiae in nude mouse , severe trabecular and cortical bone destruction and subsequent tumor growths were detected . - pubmed
The aim of this report is to introduce an on - going prospective phase II clinical trial performed to evaluate the preventive effectiveness of Lactobacillus vaginal suppositories for prevention of recurrent cystitis . - pubmed
Patients enrolled in this study are administered vaginal suppositories containing the GAI 98322 strain of Lactobacillus crispatus every 2 days or 3 times a week for one year . - pubmed
In SCI groups , rats underwent Th9 - 10 spinal cord transection followed by oral application of vehicle , naftopidil ( 20 mg / kg / day ) or tadalafil ( 2 mg / kg / day ) for 1 , 2 , 4 , 8 , and 12 weeks . - pubmed
Green tea consumption reduced the risk of PC but the results were statistically borderline . - pubmed
OBJECTIVE : The purpose of this study was to determine the safety and outcomes of VT & gt;1RFA in patients with structural heart disease . - pubmed
METHODS : Patients with structural heart disease undergoing VT RFA at 12 centers with data on prior RFA history were included . - pubmed
& gt;1RFA vs 1RFA patients did not differ with regard to age ( 62 + - 13 years vs 62 + - 13 years ) , left ventricular ejection fraction ( 33 % + - 13 % vs 34 % + - 13 % ) , or sex ( 88 % vs 87 % men ) , but they more often were nonischemic ( 53 % vs 41 % ) , had implantable cardioverter - defibrillator shocks ( 70 % vs 63 % ) or VT storm ( 38 % vs 33 % ) , and had been treated with amiodarone ( 55 % vs 48 % ) or & gt;=2 antiarrhythmic drugs ( 22 % vs 14 % ) . - pubmed
Leptomeningeal carcinomatosis in a young patient with obstructive colorectal signet - ring cell adenocarcinoma . - pubmed
We present the case report of a twenty - five - year - old Moroccan male patient who suffered from leptomeningeal carcinomatosis related to a signet - ring cell carcinoma of the rectum . - pubmed
This case shows the tendency of colorectal signet - ring cell carcinomas to cause leptomeningeal metastasis , even in young patients . - pubmed
METHODOLOGY : A prospective randomized trial involving screening of 1000 pregnant women for gestational diabetes mellitus was conducted . - pubmed
Women diagnosed with ' gestational diabetes ' were followed in an antenatal clinic , and incidence of GDM and maternal and fetal outcome between two groups were analyzed using SPSS . - pubmed
RESULTS : During period 1 , we recruited older patients ( average 65 vs 64 years ) , less often women ( 19 vs 26 % ) and having less severe airflow obstruction ( mean FEV1 48 vs 54 % ) . - pubmed
A very low calorie ketogenic diet improves weight loss and quality of life in patients with adjustable gastric banding . - pubmed
In twenty patients ( GROUP A ) we observed a stop in weight loss so we divided this patients into two groups . - pubmed
CONCLUSIONS : KD can improve the weight loss and quality of life in patients who underwent LAGB and failed at losing more weight allowing a weight loss comparable to that obtained with a further calibration and it is useful to avoid drastic calibrations and their collateral effects . - pubmed
BACKGROUND : About 25 % of hypotensive ELBW infants are refractory to intravascular volume expansion and inotropic drugs ( VI ) and require hydrocortisone ( HC ) . - pubmed
ELBW infants with refractory hypotension ( RH ) are clinically and biochemically indistinguishable from those who respond to VI . - pubmed
OBJECTIVE : Early identification and differentiation of ELBW infants susceptible to steroid dependent hypotension from those who respond to inotropic medications . - pubmed
METHODS : In a retrospective study the ante- and postnatal clinical characteristics of ELBW infants who received hydrocortisone ( HC ) for refractory hypotension ( RH ) were compared to those who responded to volume - inotropes ( VI ) . - pubmed
In this study , we explored its predictive value for treatment response and survival in metastatic renal - cell carcinoma ( mRCC ) patients . - pubmed
Pasteurella multocida , Mannheimia haemolytica and Trueperella pyogenes are three bacterial pathogens closely associated with the bovine respiratory disease complex ( BRDC ) . - pubmed
Cochlear Dysfunction is not Common in Human Meningioma of the Internal Auditory Canal . - pubmed
HYPOTHESIS : Cochlear dysfunction is not common in human meningioma of the internal auditory canal . - pubmed
METHODS : Retrospective analysis of cochlear histopathology in five unoperated and five operated meningiomas of the internal auditory canal identified after screening human temporal bone collections from three academic medical centers . - pubmed
CONCLUSIONS : Substantial cochlear damage in human meningioma of the internal auditory canal is not common . - pubmed
Rotavirus G ( RVG ) strains have been detected in a variety of avian species , but RVG genomes have been published from only a single pigeon and two chicken strains . - pubmed
Two turkey RVG strains were identified and characterized , one in a hatchery with no reported health issues and the other in a hatchery with high embryo / poult mortality . - pubmed
Low nucleotide percentage identities ( 31.6 - 87.3 % ) occurred among the pigeon and chicken RVG strains . - pubmed
The epidemiology of RVG in avian flocks and the pathogenicity of the two different RVG strains should be further investigated to understand the ecology and impact of RVG in commercial poultry flocks . - pubmed
Methods : This was a retrospective study of 153 patients who underwent Ivor Lewis esophagectomy for squamous cell carcinoma between January 2008 and December 2016 . - pubmed
Postoperative complications occurred in 17 ( 32.1 % ) and 23 ( 37.1 % ) patients in the HIL and OIL groups , respectively ( P=0.573 ) ; in - hospital mortality rates were 3.8 % and 8.1 % , respectively ( P=0.337 ) . - pubmed
Bacteria and biofilms are likely contributory but secondary drivers of inflammation . - pubmed
We present a case of profound hyponatremia of 102 mmol / L in a patient who required emergent operative repair for bowel obstruction . - pubmed
This is the first case to our knowledge that demonstrates a perioperative fluid and desmopressin treatment strategy to prevent overly rapid changes of sodium concentration in a patient with severe hyponatremia . - pubmed
CASE PRESENTATION : An 81 - year - old man was referred to our hospital with a 5 - month history of dysphagia . - pubmed
The patient was treated by thoracoscopic esophagectomy with three - field lymph node dissection and gastric tube reconstruction via a posterior mediastinal approach , under the diagnosis of esophagogastric junctional cancer ( T3N0M0 , stage IIA ) . - pubmed
Histopathological examination revealed two distinct components , namely , a neuroendocrine carcinoma component and an adenocarcinoma component , and the patient was diagnosed as having mixed adenoneuroendocrine carcinoma ( MANEC ) . - pubmed
Thereafter , the tumor became even more aggressive , and the patient died 8 months after the surgery . - pubmed
CONCLUSIONS : We report a patient with MANEC of the esophagogastric junction . - pubmed
Close attention should be paid to such patients , as MANEC can be a highly aggressive tumor , showing rapid progression . - pubmed
The efficacy of both the EOs to disrupt the preformed biofilms of various MRSA strains was determined by Confocal Laser Scanning Microscopy ( CLSM ) and Scanning Electron Microscopy ( SEM).The EOs were further able to reduce the Extracellular polymeric substance ( EPS ) and slime synthesis the two factors of the biofilm assemblage . - pubmed
METHODS : Sixty pregnant women with pulpitis were divided into the first , second and third trimester . - pubmed
MI was induced in a rat model by ligation of the left anterior descending artery . - pubmed
OBJECTIVE : To provide a comparative quantitative summary of surgical complications and postoperative seizure freedom associated with invasive extra - operative presurgical techniques in pediatric patients . - pubmed
At the time of the last postoperative visit , a greater percentage of pediatric patients achieved seizure freedom in the SEEG studies ( SEEG : 66.5 % , 95 % CI 58.8 - 73.4 ; SDG : 52.1 % , 95 % CI 43.0 - 61.1 ) . - pubmed
A 70 - year - old woman with a background of portopulmonary hypertension , managed with sildenafil and oral diuretics , and cirrhosis , presented with acute on chronic haemorrhoidal bleeding , iron deficiency anaemia and worsening right heart failure . - pubmed
We found that MERS - CoV infection induced pyroptosis and over - activation of complement in human macrophages . - pubmed
Although population expansion of cowpea bruchid ( Callosobruchus maculatus ( Fabricius ) ) could be temporarily arrested when exposed to 2 % O2 , this insect could survive extended periods of hypoxia and continue its normal development if normoxic conditions resumed . - pubmed
Early Experience With New Generation Deep Brain Stimulation Leads in Parkinson ' s Disease and Essential Tremor Patients . - pubmed
Participants treated with antenatal sGC exhibited comparable levels of hair cortisol , cortisone , dehydroepiandrosterone ( DHEA ) and cortisol / DHEA ratios compared to those of mothers who had been admitted to hospital for pregnancy complications , but had never received sGC therapy and controls from physiological pregnancies . - pubmed
High drug loading efficiency and sustained release of doxorubicin from Cy5 - functionalized p ( HEMA - ran - GMA ) nanoparticles enabled effective inhibition of the MCF-7 human breast cancer derived cell line . - pubmed
The purpose of this study was to evaluate achievement of three motor milestones ( pull - to - standing , cruising and independent walking ) in two groups of clubfoot patients treated at two experienced institutes respectively with the PM and FM . - pubmed
A Pilot Study on the Effects of l - Carnitine and Trimethylamine - N - Oxide on Platelet Mitochondrial DNA Methylation and CVD Biomarkers in Aged Women . - pubmed
Terlipressin for the treatment of septic shock in adults : a systematic review and meta - analysis . - pubmed
BACKGROUND : Catecholamines are the first - line vasopressors used in patients with septic shock . - pubmed
OBJECTIVES : To investigate the immediate effects of forearm and/or wrist orthoses on outcome measures of pain and function in individuals with lateral elbow tendinopathy . - pubmed
DESIGN : Systematic review METHODS : Four electronic databases were searched to identify randomised controlled trials reporting the immediate effects of forearm and/or wrist orthoses on pain and function in individuals with lateral elbow tendinopathy . - pubmed
Intradetrusor onabotulinumtoxinA injections ameliorate autonomic dysreflexia while improving lower urinary tract function and urinary incontinence - related quality of life in individuals with cervical and upper thoracic spinal cord injury . - pubmed
All the isolates were evaluated for their cytotoxic effects against a small panel of cultured human cancer cell lines ( HeLa , A-549 , MDA - MB-231 , SKOV3 , Huh-7 , and HCT-116 ) , and some of them exhibited cytotoxicities with IC50 values ranging from 1.5 to 10.0 muM. - pubmed
In the current study , we aimed to compare the long - term outcome of TACE + RT to that of RT alone in patients with local advanced HCC with MVI . - pubmed
Methods : In this retrospective study , 148 treatment - naive patients of HCC with MVI were enrolled . - pubmed
Two patients ( 4.1 % ) experienced radiation - induced liver disease ( RILD ) , and one ( 2.0 % ) experienced RT - related gastrointestinal ( GI ) bleed in the TACE + RT groups . - pubmed
Nine patients ( 9.1 % ) experienced RILD , and two ( 2.0 % ) experienced RT - related GI bleed in the RT groups . - pubmed
There is a distinct lack of literature surrounding the therapeutic use of nbUVB in eczema in children and especially in children with higher skin phototypes ( III to VI ) . - pubmed
METHODS : We undertook a retrospective review of children aged 18 years and under with atopic eczema who had undergone nbUVB in our department between January 1st 2011 and December 31st 2017 . - pubmed
CONCLUSION : We have demonstrated that nbUVB is a safe , well tolerated and efficacious form of treatment for children with atopic eczema . - pubmed
METHODS : After initial diagnosis by ultrasound , 124 BI - RADS - US type 4 patients with 130 lesions were examined by contrast - enhanced ultrasound ( CEUS ) and were classified again before surgery according to five contrast - enhanced malignancy imaging features : inhomogeneous enhancement , peripheral ring - like enhancement , expansive enhancement , internal filling defects , and surrounding radioactive convergence . - pubmed
Visual - Attentional Load Unveils Slowed Processing Speed in Multiple Sclerosis Patients : A Pilot Study with a Tablet - Based Videogame . - pubmed
Fifty - one patients with MS ( pwMS ) , classified as having no cognitive impairment in classic paper - and - pencil tests , and 20 healthy controls ( HC ) underwent the videogame tasks ; reaction times ( RTs ) and accuracy were recorded . - pubmed
The in vivo analysis showed that after injection , L - EGCG - Mn exhibited a higher MRI signal compared to Gd - DTPA in H22 tumor - bearing mice ( p < .05 ) . - pubmed
High - density surface electromyography to assess motor unit firing rate in Charcot - Marie - Tooth disease type 1A patients . - pubmed
OBJECTIVE : The aim of this study was to elucidate the characteristics of the motor unit ( MU ) firing rate in Charcot - Marie - Tooth disease type 1A ( CMT1A ) patients and its longitudinal change using high - density surface - electromyography ( surface - EMG ) and MU decomposition analysis . - pubmed
METHODS : Nineteen patients with CMT1A and 21 force - matched healthy controls prospectively underwent surface - EMG recording of the vastus lateralis muscle during ramp - up and sustained contractions on performing isometric knee extension . - pubmed
In CMT1A patients , follow - up measurements were performed one year after the baseline . - pubmed
Comparison of IFRs and clinical variables between CMT1A patients and controls at the baseline and between the baseline and after one year in CMT1A patients was performed . - pubmed
RESULTS : Mean IFRs of MUs were lower in CMT1A patients than in controls . - pubmed
In CMT1A patients , mean IFRs at 0 - 10 seconds of sustained contraction were significantly decreased over one year ( from 8.06 to 7.52 pps ; p = 0.027 ) , whereas the disease severity score and MVC of knee extension did not change over time . - pubmed
CONCLUSION : CMT1A patients had a lower individual MU firing rate . - pubmed
SIGNIFICANCE : The MU firing rate is a potential short - term biomarker of axonal damage in CMT1A patients . - pubmed
A phenotype - specific analysis of model performance was afforded by the annotations included in the St. Petersburg INCART Arrhythmia database CONCLUSION : The five features this novel algorithm employed allowed our ventricular ectopy detector to obtain high precision on previously unseen subjects and databases SIGNIFICANCE : Our ventricular ectopy detector will be used to study the relationship between premature ventricular contractions and adverse patient outcomes such as congestive heart failure and death . - pubmed
Clinical and sural nerve biopsy findings are described in four hypothyroid patients with manifestations of a diffuse peripheral neuropathy . - pubmed
In one patient , signs of the peripheral neuropathy comprised the leading symptomatology of the underlying metabolic disorder . - pubmed
Dystrophic and degenerative changes in axons of all fiber classes and the presence of clusters of thinly myelinated small fibers suggest that neuroaxonal degeneration and incomplete regeneration may represent the major pathogenetic mechanism of the neuropathy in these hypothyroid patients . - pubmed
for the two components of weight loss in the mouse testis for fast neutrons relative to X - rays . - pubmed
The " return " of influenza A ( HINI ) virus after 20 years of absence raised the question of the sources and mechanisms of emergence of epidemic influenza viruses and , particularly , of a new HINI virus ( A / USSR / 90 / 77 ) . - pubmed
Two alternative hypotheses answer this question differently : the new HINI virus is the progeny of old HINI viruses retained in the human population or is a newly arising recombinant between numerous human and animal influenza viruses circulation in the biosphere . - pubmed
The blood glucose lowering properties of the two hydrazones were most manifest in fasted guinea pigs , diabetic mice and rats with streptozotozin diabetes . - pubmed
Exaggerated natriuresis in response to hypertonic saline infusion occurs with great regularity in patients with documented previous attacks of poststreptococcal glomerulonephritis . - pubmed
In all patients , extracellular fluid volume decreased during sodium restriction , as judged by weight loss , cumulative negative sodium balance , small decreases in measured plasma volume , and appropriate increases of PRA and plasma aldosterone concentration . - pubmed
A comparison of Salmonella dublin infection in normal and endotoxin - tolerant mice . - pubmed
Changes in general haemodynamics and renal function during exercise in patients with arterial hypertension . - pubmed
Basic haemodynamic parameters were measured in 58 men in various stages of essential hypertension , 18 patients with hypertensive form of chronic glomerulonephritis , and 23 practically healthy persons during graded exercise in the supine position on a bicycle ergometer for 30 minutes . - pubmed
During exercise , the systolic pressure rose in all persons investigated , whereas the diastolic pressure markedly increased only in patients with arterial hypertension . - pubmed
Renal blood flow and glomerular filtration decrease during exercise , both in healthy untrained persons and in patients with arterial hypertension . - pubmed
In patients in late stages of essential hypertension and in those with glomerulonephritis , the above parameters decrease more markedly and at lower exercise intensity than in healthy persons . - pubmed
Moreover , although CAPD patients seem to have better control of serum phosphate concentration than hemodialysis patients , the need for aluminum - containing phosphate binders ( ACPB ) may still be present . - pubmed
In a prospective study meant to investigate the evolution of RO , we obtained 79 bone biopsies in 29 uremic patients ( 20 male , 9 female ; age 25 - 59 , mean 46 ) . - pubmed
The highest bone Al content was found among patients with predominant osteoid bone disease . - pubmed
Also in CAPD , patients consuming ACPB are at risk of bone Al accumulation despite the low Al levels in the dialysate . - pubmed
Replantation of an autoclaved , autogenous humerus in a patient who had chondrosarcoma . - pubmed
A 33 - year - old woman who was a chronic alcohol abuser and had bilateral visual loss was found to have megaloblastic anemia with thrombocytopenia . - pubmed
Comparative evaluation of the immune status of congenitally athymic and euthymic rat strains bred and maintained at different institutes : 1 . - pubmed
We performed a comparative evaluation of the immune status , focused on the T - cell system , of euthymic rat strains in which the nude mutation had been introduced . - pubmed
Proteoglycans from the swarm rat chondrosarcoma . - pubmed
Proteoglycan aggregates were extracted from Swarm rat chondrosarcoma tissue in the native state and compared with proteoglycan aggregates isolated dissociatively with 4 M guanidine HCl . - pubmed
Three SMMX - resistant strains of B. - pubmed
[ Occurrence of subdural hematoma closely associated with danazol administration in a patient with refractory ITP ] . - pubmed
It is strongly suggested that danazol should be very carefully administered in ITP patients with serious bleeding tendency . - pubmed
As reports become available on human gastroenteritis caused by the atypical or novel rotaviruses , this technique presents an added advantage in that it can detect both group A and non - group A rotaviruses . - pubmed
Portal hypertension ameliorates arterial hypertension in spontaneously hypertensive rats . - pubmed
Systemic hemodynamic effects of portal hypertension in arterial hypertension and their relationship to serum bile acid levels were investigated using spontaneously hypertensive rats 2 and 15 weeks after partial portal vein ligation ( SHR - PVL ) or sham operation ( SHR - SH ) and normotensive controls . - pubmed
Animal data show that noradrenaline deficiency results in scattered attention . - pubmed
The cortical motor areas are relatively spared from neuro - degenerative changes in normal aging and in AD / SDAT and this might provide a neuroanatomical basis for the elderly 's and mildly to moderately demented patients ' success in memory performance when motor action is involved . - pubmed
This is an illustrative case of a patient with neuroleptic malignant syndrome whom we believe is the first described in the world 's literature to have this syndrome on three occasions , each time after having received a different neuroleptic agent . - pubmed
10 stable asthmatics , 9 females and 1 male , all on regular inhaled bronchodilators and steroid treatment , were studied following prior assessment of reversibility . - pubmed
The hemodynamic pattern in patients with cirrhotic liver disease shows a hypercirculatory state , with elevated cardiac output and decreased systemic vascular resistance . - pubmed
[ Do converting enzyme inhibitors give a better protection against cerebral vascular complications in hypertensive patients ? ] - pubmed
Structural rearrangement of the retinoblastoma gene in human breast carcinoma . - pubmed
Structural changes of the human retinoblastoma gene have been demonstrated previously in retinoblastoma and some clinically related tumors including osteosarcoma . - pubmed
The histology findings of pre - clinical neoplasia of the cervix at cone biopsy were compared with the previous colposcopic assessment in fifty - eight patients . - pubmed
A 25 - year - old white man presented with acute multiple sclerosis manifested by right blindness , difficulty urinating , and paresthesias and weakness of both legs . - pubmed
We describe a 68 - year - old woman with a benign hemangioma that presented clinically as a very large ovarian mass . - pubmed
Curare and pancuronium have multiple effects on previously undepressed rat diaphragm ; these include depression of transmitter output and prolongation of the refractory period of prejunctional structures . - pubmed
[ Optic nerve injury in a patient with osteogenesis imperfecta tarda ] . - pubmed
In a patient with myasthenic syndrome neuro - muscular transmission was characterised by depression and facilitation . - pubmed
Hyperprolactinaemia was induced during March in 2 - year - old rams which had regressed testes . - pubmed
Serum CMV antibody titers have been measured over a period starting prior to transplantation as an approach to diagnosis of cytomegalovirus ( CMV ) infection following renal transplantation . - pubmed
A myeloid cell line , designated PL-21 , was established from the peripheral blood of a patient with acute promyelocytic leukemia . - pubmed
Chromosome analysis of this cell line revealed a human male polyploid karyotype with 13q+ and double minute chromosomes . - pubmed
From echocardiographic measurements , 39 patients with established , uncomplicated primary hypertension ( diastolic pressure & gt ; 100 mmHg ) were classified as follows : normal - sized heart ( group 1 , 10 cases ) ; concentric left ventricular hypertrophy ( group 2 , 18 cases ) ; left ventricular hypertrophy and cavity enlargement ( group 3 , 11 cases ) . - pubmed
At variance with previous conclusions ( which were based on utilisation of electrocardiographic and chest x - ray criteria to define hypertrophy ) it is suggested that left ventricular concentric hypertrophy in man consequent to sustained hypertension is associated with an improved function . - pubmed
Medical problems of geriatric psychiatric patients and younger controls during electroconvulsive therapy . - pubmed
Thirty - seven arthritis patients participating in a drug withdrawal trial , simultaneously completed a 20 - point visual analogue scale and 7 - point verbal rating scale for pain severity while on active medication and 48 hours following its withdrawal . - pubmed
This is in good agreement with the value of 50 micrograms previously estimated for honey bee stings and is the first reported data for the other species . - pubmed
Nine children with airway obstructing hemangiomas were managed with corticosteroid therapy for durations of 6 weeks to 17 months . - pubmed
Therapy was continued for 8 months or longer in 6 patients , none of whom developed life - threatening infections . - pubmed
Steroid therapy is an effective method of protecting the airway in some patients with hemangiomas . - pubmed
[ Evaluation of possible secondary prevention of periodontal diseases in selected patients ] . - pubmed
Normal response to pregnancy in rats cured of streptozotocin diabetes by transplantation of one fetal pancreas . - pubmed
The most frequent and severest toxicity was nausea and vomiting seen in about the half of patients being administered dosages ranged from 24 mg / m2 to 40 mg / m2 , and 3 out of 4 patients received dosages exceeding 50 mg / m2 required clinical managements ; moreover , 1 out of 2 patients administered 60 mg / m2 was ranked as grade 4 of the criterion of toxicities in WHO handbook . - pubmed
Other clinical toxicities such as skin rash , hepatotoxicity or nephrotoxicity observed in the minority of the patients were reversible . - pubmed
One patient with chronic myelogeneous leukemia had a hematological improvement and the other with esophageal cancer had a partial response . - pubmed
Hemolysis - induced gallstones in mice : increased unconjugated bilirubin in hepatic bile predisposes to gallstone formation . - pubmed
We recently reported that nb / nb mice with hereditary hemolytic anemia spontaneously developed calcium bilirubinate gallstones . - pubmed
Recent studies hypothesized the involvement of nitric oxide in motility disorders of the human gut . - pubmed
Panniculectomy as an integral part of pelvic operation is an underutilized technique in patients with morbid obesity . - pubmed
Fifteen patients had significant medical problems and nine of the 16 had an umbilical hernia . - pubmed
All but one of the wounds healed by first intention , and in that patient , an 8 cm segment was easily resutured . - pubmed
There was no increased blood loss associated with the panniculectomy , but of note is the fact that the hematocrit level decreased in five patients on days 2 to 5 postoperatively without hematoma formation . - pubmed
Congo red was bound from solution by strains of Porphyromonas gingivalis including W50 , HG189 , HG184 , NCTC 11834 , Bg 381 , WPH35 , the slower brown pigmenting colonial variant W50 / BR1 , and the avirulent mutant W50 / BE1 , and by Porphyromonas endodontalis HG370 and Porphyromonas asaccharolytica B537 . - pubmed
These data , and our previous work , show that Congo red and iron protoporphyrin IX ( haemin ) are bound to different outer - membrane components , and that Congo red binding may be of little value as a marker to detect virulent strains of P. - pubmed
[ Primary treatment of unstable pertrochanteric femoral fractures using a head - neck prosthesis in elderly patients ] . - pubmed
OBJECTIVE : Evaluation of the treatment of unstable pertrochanteric femoral fractures with a femoral head prosthesis in older patients . - pubmed
METHOD : From January 1988 through December 1992 , 15 patients with 15 unstable pertrochanteric femoral fractures were treated with a femoral head prosthesis and additional wiring of the trochanter . - pubmed
A patient who had undergone myocardial revascularization with a saphenous vein graft to the left anterior descending artery and a left internal thoracic ( mammary ) artery graft to the 1st diagonal branch presented with an unusual form of subclavian steal syndrome . - pubmed
We report a patient with a slowly progressive polyneuropathy associated with substantial slowing of conduction velocities initially suggestive of an acquired or hereditary demyelinating polyneuropathy . - pubmed
Sialadenitis associated with periorbital disease in a dog . - pubmed
Submucosal sialadenitis was diagnosed on histologic examination of a biopsy specimen from a palatine swelling associated with acute , unilateral periorbital disease in a dog . - pubmed
Intraoperative brachytherapy using I-125 pellets was reported to provide significant palliation and meaningful prolongation of life in highly selected patients with unresectable carcinoma of the pancreas . - pubmed
Between December 1989 and December 1993 , 15 patients with biopsy - proven unresectable adenocarcinoma of the pancreas were treated with interstitial Pd-103 implants during laparotomy . - pubmed
Pain relief was obtained within 3 - 6 weeks in 10 out of 12 patients presenting with pain . - pubmed
However , this study did not show any improvement in the median survival rate over I-125 due to the advanced stage cancer in the majority of patients in the study . - pubmed
The performance of broilers was examined under different days of placement ( after hatching ) and with three different types of waterers : 1 ) an automatic satellite waterer ; 2 ) a broiler Plasson waterer ; and 3 ) a regular Plasson waterer with a plastic ring in the trough of the waterer for 3 d. Male broiler chicks ( 2,106 ) from a commercial strain were randomly placed in 27 litter floor pens , with 9 pens per day of placement and waterer treatments . - pubmed
There was a difference in body weight ( P & lt ; .05 ) among the broilers on the day of placement , with those on the day of hatch being heavier . - pubmed
There was no difference in body weights or feed conversion taken after the broilers were on feed for 7 and 49 d after placement . - pubmed
There was no difference in body weight , feed conversion , or mortality within the three different waterer treatments except for the broilers on the Plasson with the ring , which was higher in mortality percentage ( P & lt ; .05 ) than the broilers on the broiler Plasson waterer . - pubmed
STUDY DESIGN : A prospective , randomized clinical trial of patients with the diagnosis of postpartum endometritis . - pubmed
RESULTS : One hundred twenty - nine hospitalized women with the diagnosis of endometritis were enrolled . - pubmed
OBJECTIVE : To assess the degree of variability of transient myocardial ischaemia during daily life in patients with coronary artery disease , which could confound the interpretation of trials of the therapeutic effects of anti - ischaemic agents . - pubmed
PATIENTS : Patients with stable angina , confirmed coronary artery disease , and a positive treadmill exercise test for ischaemia . - pubmed
Patients were not preselected on the basis of prior documented transient ischaemia during ambulatory ST segment monitoring . - pubmed
RESULTS : There was marked variability in both ischaemic activity and mean duration of ischaemia in patients with confirmed ischaemia , the greatest degree of variability being between patients and from day to day within weeks within patients , with a further contribution to variability being noted between fortnights within patients . - pubmed
The strain patterns associated with normal activities were established for the rat ulna from strain gauges implanted in vivo . - pubmed
These experiments show that the growing rat ulna underwent adaptive changes in both bone mass and architecture when short daily periods of axial loading , producing strains within the physiological range and with near normal strain distribution , were superimposed on the loading associated with normal activity . - pubmed
Ovariectomy - induced bone loss can be affected by different intensities of treadmill running exercise in rats . - pubmed
These results suggest that bone in OVX rats is either more sensitive to exercise than in sham - operated rats or that the higher body weight with slow running induces optimal loading and strengthens the bones . - pubmed
In experiments to translate this into a role in pathogenicity , wild - type and mutant organisms were used in an intraperitoneal mouse infection model . - pubmed
Patients were divided into 325 subjects without cardiovascular risk factors and 895 subjects with cardiovascular risk factors ( 352 with arterial hypertension alone , 298 with arterial hypertension associated with other cardiovascular risk factors , 245 with hypercholesterolemia , diabetes , cigarette smoking , alone or associated ) . - pubmed
A preliminary anatomic - functional model , assembled from facts of human paleoneuropsychiatry , more adequately contextualises manic - depressive genomics and phenotypy . - pubmed
Multiple genetic alterations , 4q28 , a new suppressor region , and potential gender differences in human hepatocellular carcinoma . - pubmed
The main purpose of this pilot study was to evaluate HFOV on adult trauma patients with refractory lung dysfunction . - pubmed
In conclusion , all patients improved after initiation of HFOV , and HFOV should be considered in the treatment of patients with acute refractory lung dysfunction . - pubmed
Ionized magnesium supplementation in critically ill patients : comparing ionized and total magnesium . - pubmed
PURPOSE : The purpose of this study was to assess the effect of magnesium supplementation on total magnesium , ionized magnesium , ionized calcium , potassium , and pH in critically ill cancer patients and to compare the validity of the measurements . - pubmed
MATERIALS AND METHODS : Thirty - three consecutive critically ill patients receiving magnesium supplementation were placed in this prospective observational study at the Comprehensive Cancer Center , University Hospital . - pubmed
The recombinants were scored by plating lysates on the amber - suppressor Escherichia coli strain , on which an amberlike mutation was not expressed phenotypically . - pubmed
Thirty - three patients ( rheopheresis group , 17 ; control group , 16 ; mean age 64 + /- 10 years ) with acute ischemic stroke were included in our prospective randomized trial . - pubmed
CLINICAL CASE : We describe the case of a 69 year old female patient with all the symptoms of Wallenberg ' s syndrome and two potential causes of stroke ( emboliogenic cardiopathy and atherothrombotic vascular occlusion ) , in whom MR showed the presence of an isolated bulbar lesion of unusual morphology which had previously been described as being of thrombotic origin . - pubmed
A case of a degloving injury to the foot is presented in a patient who also sustained severe contralateral lower - limb trauma . - pubmed
In patients with chronic hepatitis C , HCV RNA remained detectable in all patients . - pubmed
In conclusion , antiviral activity of rHuIL-12 in patients with chronic hepatitis B or C does not appear to be advantageous in comparison to other currently available treatments . - pubmed
The median survival time for patients with TS & lt;or= 7.5 x 10(-3 ) ( 43 of 50 patients ) was 10.2 months , compared with 1.5 months for patients with TS greater than 7.5 x 10(-3 ) ( P & lt ; .001 ) . - pubmed
Sulphasalazine - induced systemic lupus erythematous in a patient with ankylosing spondylitis . - pubmed
In obese and particularly in morbidly obese women suffering from skin friction , urinary stress incontinence , varicose veins , foot static problems and pain , wearing insoles , suffering from knee pain , low back pain or hip arthritis were significantly more prevalent than in lean women ( P & lt ; 0.05 ) . - pubmed
Between 1991 and 1995 , a total of 29 patients with cancer of the hypopharynx were treated using laser surgical resection . - pubmed
The highest local control rate was achieved in patients with carcinoma of the hypopharyngeal walls . - pubmed
There were no functional deficits regarding speech and swallowing in 94 % , 100 % and 100 % of the surviving patients without local recurrence after 3 , 4 and 5 years , respectively . - pubmed
Laser surgical treatment in combination with neck dissection and postoperative radiotherapy of selected patients with early cancer of the hypopharynx shows comparable results with open surgical procedures and is superior to radiotherapy alone . - pubmed
Beclomethasone dipropionate ( BDP ) is a potent pro - drug to beclomethasone ( BOH ) and is used in the treatment of chronic and acute respiratory disorders in the horse . - pubmed
[ ELASTOTONOMETRIC AND GONIOSCOPIC EXAMINATION IN PATIENTS WITH DIABETES MELLITUS ] . - pubmed
A SPECIAL CARE UNIT FOR CHILDREN WITH SEVERE DUAL MENTAL AND PHYSICAL HANDICAP . - pubmed
Review of one hundred hemiplegic patients . - pubmed
The purpose of this study was to determine the frequency with which patients report paresthesia at the point that an acceptable motor response is obtained to low - intensity current electrical stimulation . - pubmed
During nerve localization and while maintaining a motor response ( 0.20 mA-0.40 mA ) , the patients were queried regarding any radiating sensation or pain ( paresthesia ) in the shoulder or extremity on the side of the blockade . - pubmed
None of the patients spontaneously reported having a paresthesia during nerve stimulation . - pubmed
However , on careful questioning , half of the patients ( 55 % ) reported electrical paresthesia , defined as dull tingling sensation traveling down to their hands and coinciding with the motor response . - pubmed
In addition , most patients ( 71 % ) spontaneously reported having a mild , radiating paresthesia on initial injection of local anesthetic . - pubmed
A 44 - year - old man presented with a large and rapidly growing skin lesion approximately six months after resection of a rectal carcinoma . - pubmed
The clinical outcome of patients who have undergone liver transplantation for hereditary hemochromatosis ( HH ) or who have received iron - loaded donor grafts is unclear . - pubmed
We reviewed 3,600 adult primary orthotopic liver transplants and assessed the outcomes in 22 patients with HH . - pubmed
HH patients had comparatively poor outcomes following transplantation : survival at 1 , 3 , and 5 years posttransplantation were 72 % , 62 % , and 55 % , respectively . - pubmed
These recipients had appropriate early graft function , but 2 patients with heavy iron loading and increased hepatic iron developed hepatic fibrosis . - pubmed
This review evaluates the evidence that underlies the hypothesis that an energy deficit is instrumental in the disturbance of bone turnover that has been observed in physically active individuals . - pubmed
Transthoracic tissue Doppler study of right ventricular regional function in a patient with an arrhythmogenic right ventricular cardiomyopathy . - pubmed
Several new endovascular devices have been successfully tested for safety in acute ischemic stroke patients and are now being tested for efficacy in larger clinical trials . - pubmed
Chromosomal instability predicts metastatic disease in patients with insulinomas . - pubmed
Although the behavioral profiles typically associated with an increased risk for STI ( including lifetime partner number , age at first intercourse , and so forth ) will certainly lead to an increased risk for HPV detection , there is a high absolute prevalence of HPV even among women who have few lifetime sex partners . - pubmed
Many programmatic issues remain regarding the implementation of HPV vaccine programs , including the marketing of the vaccine as STI or cancer prevention , as reviewed in detail by Gravitt and Shah [ 72 ] . - pubmed
Therefore , although the public health success of HPV vaccination is undoubtedly promising , the role of cervical cancer screening as a secondary prevention effort should not be trivialized . - pubmed
PURPOSE : Effective and tolerable palliative treatments are needed for patients with incurable squamous cell carcinoma of the head and neck ( SCCHN ) . - pubmed
PATIENTS AND METHODS : Nineteen patients with unresectable recurrent locoregional and/or distant metastatic SCCHN with progressive disease after at least one prior chemotherapy or chemoradiotherapy regimen were enrolled onto this single - institution phase I study . - pubmed
BACKGROUND : Platanus acerifolia is an important cause of pollinosis in Western European cities . - pubmed
During saline , the vasodilator response to acetylcholine was significantly blunted ( P=0.008 ) in patients with metabolic syndrome ( n=12 , 5 female ) compared with controls ( n=12 , 7 female ) , whereas the vasodilator response to SNP was not different between groups ( P=0.68 ) . - pubmed
However , many clinicians find management of weight gain in olanzapine treated patients a challenge . - pubmed
Phalangeal bone ultrasound is of limited value in patients with juvenile idiopathic arthritis . - pubmed
OBJECTIVE : In children with juvenile idiopathic arthritis ( JIA ) , alterations of the skeletal system have been described . - pubmed
The aim of this cross - sectional study was to evaluate a phalangeal bone ultrasound device in the assessment of the skeletal status in children with active JIA . - pubmed
METHODS : In 49 children with oligoarticular , polyarticular or systemic JIA , the speed of an ultrasound signal ( Ad - SOS ) through the phalanges of the dominant hand was measured using the Igea 1200 . - pubmed
A patient with obstructive jaundice , a tumour of the pancreatic head , CBD wall thickening , and pre - existing PVT is presented . - pubmed
OBJECTIVE : To test the effect of serial magnetic resonance ( MR ) coregistration on short - term brain volume changes using different semiautomated and automated brain volume techniques in patients with relapsing - remitting ( RR ) multiple sclerosis ( MS ) . - pubmed
However , the effect of coregistration on measurement of whole brain volume changes from serial scans in the short term has not been tested in MS patients . - pubmed
The neutralizing Ab responses as measured by peptide ELISA varied greatly between individual pigs infected with each PRRSV strain . - pubmed
Urodynamic findings in female patients with urinary incontinence with intrinsic sphincteric deficiency . - pubmed
BACKGROUND : The aim of the study was to evaluate differences in urodynamic findings in women with urinary incontinence between subjects with or without intrinsic sphincter deficiency ( ISD ) . - pubmed
MATERIAL / METHODS : Sixty consecutive female patients with a history and urodynamically confirmed diagnosis of pure urinary incontinence were evaluated . - pubmed
A new drug might make a positive contribution to existing therapies for hypertension by : 1 ) reducing blood pressure ( BP ) via a novel pharmacologic mechanism ; 2 ) possessing pharmacologic or pharmacokinetic properties that make it superior to other members of its class ; or 3 ) facilitating BP control in refractory patients . - pubmed
Dendritic cells play a crucial role in initiating tumour immunity as well as in the immune response for invading foreign pathogens such as bacteria and viruses . - pubmed
In this review , the functional roles of tumour - associated iDCs and the strategy for targeting iDCs in effective tumour immunity for the cancer patient are discussed . - pubmed
Nasal obstruction in children may also be a symptom of multiple benign nasal and allergic disorders , making the initial diagnosis of meningoencephalocele difficult . - pubmed
RESULTS : Two children , ages 15 months and 6 years , underwent successful endoscopic closure of their anterior skull base defects and resection of their intranasal meningoencephalocele with resolution of their nasal obstruction and cerebrospinal fluid rhinorrhea . - pubmed
These results eliminate spontaneous mutation , between - strain complementation , and heterotypic resistance as general explanations of multiply resistant C. - pubmed
The aim of this study ( Alfacalcidol Alendronate Combined - AAC ) was to compare the efficacy and safety of a combined parallel therapy with Alendronate and Alfacalcidol to the treatment with either Alendronate in combination with plain vitamin D or Alfacalcidol alone in patients with established postmenopausal or male osteoporosis . - pubmed
We found 80 % of the patients in the Alendronate + Alfacalcidol group free from back pain at month 24 , compared to 30 % in the Alendronate + vitamin D and 43 % in the Alfacalcidol monotherapy group . - pubmed
INTRODUCTION : Patients with moderate or severe traumatic brain injury ( TBI ) may show impairment in decision- making processes . - pubmed
OBJECTIVE : Investigate decision - making in patients with moderate or severe TBI during performance of the IGT , and study patient 's conscious knowledge of the task 's reinforcement contingencies ( reward / punishment schedule ) . - pubmed
PATIENTS AND METHODS : Forty patients with moderate or severe TBI and 30 healthy volunteers participated in the study . - pubmed
IGT score differences were observed among TBI patients in relation to level of knowledge of the task . - pubmed
CONCLUSIONS : These results suggest that there is a direct relationship between the knowledge that patients with moderate and serious TBI have regarding the TBI reinforcement contingencies and their performance in the task . - pubmed
Stent implantation as a treatment option in patients with thoracic anastomotic leaks after esophagectomy . - pubmed
BACKGROUND : In patients with esophagectomy and gastric pull up for esophageal carcinoma anastomotic leaks are a well - known complication and a major cause of morbidity and mortality . - pubmed
OBJECTIVE : We evaluated stent implantation as a treatment option in patients with thoracic anastomotic leaks after esophagectomy . - pubmed
METHODS : 269 patients with esophageal cancer ( adenocarcinoma n = 212 , squamous cell carcinoma n = 57 ) had undergone esophagectomy and gastric pull up with an intrathoracic anastomosis between January 1998 and December 2005 . - pubmed
A thoracic anastomotic leak was clinically and endoscopically proven in 12 patients ( 4.5 % ) . - pubmed
CONCLUSION : Stent implantation in patients with thoracic anastomotic leaks after esophagectomy is an easily available and effective treatment option with low morbidity , but stent migration does occur . - pubmed
Based on increased exhaled NO ( eNO ) levels in patients with asthma , eNO analysis has been proposed as a novel , noninvasive approach to the assessment and monitoring of airway inflammation , and as a basis for adjustments in asthma therapy . - pubmed
INTRODUCTION : Positron emission tomography ( PET ) imaging with copper ( II )- diacetyl - bis ( N4 - Methylthiosemicarbazone )( Cu - ATSM ) for delineating hypoxia has provided valuable clinical information , but investigations in animal models of prostate cancer have shown some inconsistencies . - pubmed
Helicobacter pylori is a chronic infectious agent defined as the major pathogen causing gastritis , gastric and duodenal ulcer , gastric carcinoma and mucosa associated lenfoid tissue ( MALT ) lymphoma . - pubmed
BACKGROUND : Inguinal hernia in children is traditionally repaired through a groin incision by dissecting the hernia sac from the spermatic cord and suture ligating its base . - pubmed
METHODS : Prospective review of 275 hernias in 187 children ( 144 male , 43 female ) performed laparoscopically by a single surgeon between September , 2002 and June , 2005 . - pubmed
Four out of 275 hernias ( 1.5 % ) recurred in four patients ( mean age 4.5 years ; 3 male , 1 female ) . - pubmed
CONCLUSION : This novel laparoscopic inguinal hernia repair is an effective method in children , with recurrence rates comparable to the traditional approach . - pubmed
Klebsiella oxytoca bacteremia causing septic shock in recipients of hematopoietic stem cell transplant : Two case reports . - pubmed
Eight days following her autograft she developed septic shock caused by Klebsiella oxytoca bacteremia which was successfully treated with intravenous meropenem and gentamicin . - pubmed
Seven months following her unsuccessful allograft , she developed septic shock due to Klebsiella oxytoca bacteremia caused by a urinary tract infection . - pubmed
To our knowledge , they are the first reports of Klebsiella oxytoca bacteremias and septic shocks in hematopoietic stem cell transplant recipients . - pubmed
CONCLUSION : Klebsiella oxytoca should be considered as a possible cause of severe infections in recipients of various forms of hematopoietic stem cell transplantation . - pubmed
The study groups were : Control- non diabetic controls ( n=40 ) ( M : F 19:21 ) and type 1 diabetic patients ( n=75 ) ( M : F 42:33 ) . - pubmed
RESULTS : Patients with type 1 diabetes had significantly lesser joint mobility ( p & lt ; 0.0001 ) and higher plantar pressure ( p & lt ; 0.0001 ) compared with the control group . - pubmed
CONCLUSION : In conclusion , type 1 diabetic patients in India had limited joint mobility which decreased further with longer duration of diabetes and they had high plantar pressure also . - pubmed
Newly discovered ebola virus associated with hemorrhagic fever outbreak in Uganda . - pubmed
Over the past 30 years , Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever ( HF ) outbreaks with case fatalities ranging from 53 % to 90 % , while a third species , Cote d'Ivoire ebolavirus , caused a single non - fatal HF case . - pubmed
Due to the sequence divergence of this new virus relative to all previously recognized ebolaviruses , these findings have important implications for design of future diagnostic assays to monitor Ebola HF disease in humans and animals , and ongoing efforts to develop effective antivirals and vaccines . - pubmed
Finally , conjugated linoleic acid , which effectively lowers body weight in animals , has no such effect in humans in the quantities provided by dairy products . - pubmed
AIMS AND OBJECTIVES : To evaluate the concurrent validity and reliability of the behavioural COMFORT and a modified version of the FLACC scale for assessment of pain and sedation in intubated and ventilated children and to evaluate the construct validity of the FLACC scale for assessment of pain . - pubmed
RELEVANCE TO CLINICAL PRACTICE : The use of validated scales may improve the assessment and management of pain and sedation in intubated children . - pubmed
MATERIALS AND METHODS : Wistar rats receiving total body irradiation of ( 60)Co gamma - rays alone or with combined radiation and skin wound injury were used in this study . - pubmed
RESULTS : Topical application of W(11)-a(12 ) into skin wounds in rats with combined 6 Gy total body irradiation and skin wound injury could increase the neutrophils and macrophages in the wounded area and the nucleated cells in bone marrow at 24 h and 48 h , while the peripheral white blood cells did not show significant change . - pubmed
We report a series of patients undergoing radiofrequency catheter ablation of ventricular arrhythmias ( VAs ) using RMN with either a 4 - mm catheter tip or an 8 - mm catheter tip at four different centers . - pubmed
RESULTS : Twenty - eight patients ( 43 % ) had ischemic cardiomyopathy [ coronary artery disease ( CAD ) ] , 16 patients ( 25 % ) had non - ischemic cardiomyopathy [ idiopathic dilated cardiomyopathy ( IDC ) ] , and 21 patients ( 32 % ) had structurally normal hearts ( SNH ) or right ventricle outflow tract tachycardia ( RVOT ) . - pubmed
In patients with structural heart disease ( CAD , IDC ) , success was achieved in 22 % with the 4 - mm catheter tip and in 59 % with the 8 - mm catheter tip ( p = 0.014 ) . - pubmed
In patients with SNH / RVOT , success was achieved in 85 % with the 4 - mm catheter tip and in 87 % with the 8 - mm catheter tip ( p = 1.00 ) . - pubmed
Such pits may be revealed by late complications such as orbital compressive cyst of the optic nerve , even in previously normal adult patients . - pubmed
Key conclusions are ( 1 ) human research with intranasal oxytocin has uniquely enhanced our understanding of the microstructure and function of the human social brain , and ( 2 ) the oxytocin system is a promising target for therapeutic interventions in a variety of conditions , especially those characterized by anxiety and aberrations in social function . - pubmed
Because only a few studies have focused on the flavonoid structural requirements for neuroprotection , this work evaluated the protective capacity of 13 flavones structurally related to quercetin , isolated from Kenyan plants , to rescue primary cerebellar granule neurons from death induced by a treatment with 24 h of hydrogen peroxide ( 150 microM ) . - pubmed
Multiple follicular cysts of the ear canal in a dog . - pubmed
This is the first report of multiple follicular cysts originating from the ear canal in a dog . - pubmed
METHODS : We conducted a prospective observational study from March 2004 to September 2005 with consecutive infants ( ages 1 - 12 months ) with severe acute bronchiolitis and considered ready to be extubated . - pubmed
Neither age greater than 35 years nor the presence of hepatitis B virus core antibody was associated with INH - hepatitis . - pubmed
We find that birth - death models of operon evolution reasonably describe the relative abundance of operons of different sizes in the C. - pubmed
Central sleep apnoea syndrome is seen in approximately 40 % of patients with congestive heart failure . - pubmed
Sleep apnoea is associated with an increased mortality in patients with systolic heart failure . - pubmed
Because of its high prevalence , poor quality of life , poor outcome , and the beneficial effects of treatment , physicians treating patients with heart failure should be aware of central sleep apnoea . - pubmed
Lipoprotein subclasses determined by nuclear magnetic resonance spectroscopy and coronary atherosclerosis in patients with rheumatoid arthritis . - pubmed
OBJECTIVE : Patients with rheumatoid arthritis ( RA ) are at increased risk of atherosclerosis , but routine lipid measurements differ little from those of people without RA . - pubmed
METHODS : We measured lipoprotein subclasses by NMR in 139 patients with RA and 75 control subjects . - pubmed
PURPOSE : To investigate the incidence , clinical features , pathogenic bacteria , and risk factors associated with acute prostatitis after transrectal prostate biopsy . - pubmed
The incidence of acute prostatitis after transrectal prostate biopsy was 2.0 % , and almost all cases were caused by fluoroquinolone - resistant E. - pubmed
Amidst a shortage of mental health professionals and against the backdrop of natural disasters , continued terrorism , and pandemic influenza , there is a striking need to expand and operationalize available human resources to enhance the psychological resiliency of those affected . - pubmed
Secondary hyperaldosteronism in a patient with polyarteritis nodosa and renal artery aneurysms . - pubmed
PURPOSE : We wanted to evaluate the impact of fentanyl matrix on the pain and function of patients with spinal disorder - related chronic , non - malignant pain . - pubmed
OVERVIEW OF LITERATURE : Patients with severe non - malignant chronic low back pain may require opioid analgesics for effective pain management . - pubmed
METHODS : A total of 1,576 patients with severe pain ( numeric rating scale = 7 ) were evaluated for their pain intensity at the initial visit and at weeks 4 and 8 ( Visits 1 , 2 , and 3 , respectively ) . - pubmed
Few studies have evaluated the effect of cinacalcet on anemia associated with SHPT in dialysis patients , while no study has compared this cinacalcet effect with that of vitamin D analogs such as paricalcitol . - pubmed
[ Effect of quercetin on neural stem cell proliferation in the subventricular zone of rats after focal cerebral ischemia - reperfusion injury ] . - pubmed
OBJECTIVE : To study the effect of quercetin on the proliferation of neural stem cells in the subventricular zone ( SVZ ) of rats after focal cerebral ischemia . - pubmed
METHODS : An adult rat model of middle cerebral artery occlusion ( MCAO ) model was established by placement of an intraluminal filament at the origin of the MCA . - pubmed
Quercetin was administered intraperitoneally in the rats at a dose of 50 mg / kg every 3 days starting at 6 h after MCAO , and BrdU ( 50 mg / kg daily ) was also injected intraperitoneally starting at 4 h after MCAO . - pubmed
RESULTS : Compared with the sham - operated group , the rats in the ischemic model group showed significantly increased BrdU - positive cells in the ipsilateral SVZ 7 days after MCAO , reaching the peak level on day 14 and beginning to decrease on day 21 ( P<0.05 ) . - pubmed
CONCLUSION : Quercetin can maintain a high level of neural stem cell proliferation in the SVZ after focal cerebral ischemia in adult rats . - pubmed
A new assay system for evaluation of developmental immunotoxicity of chemical compounds using respiratory syncytial virus infection to offspring mice . - pubmed
We evaluated the effect of 6 - propyl-2 - thiouracil ( PTU ) , an anti - thyroid agent , on developmental immunity using respiratory syncytial virus ( RSV ) infection to offspring mice as a new risk assessment for brominated flame retardants ( BFRs ) , because some BFRs are suspected of affecting the thyroid system . - pubmed
Histopathological analysis revealed that PTU - exposure exacerbated pneumonia in RSV - infected offspring . - pubmed
Human behaviors determine health : strategic thoughts on the prevention of chronic non - communicable diseases in China . - pubmed
Prognosticators and risk grouping in patients with lung metastasis from nasopharyngeal carcinoma : a more accurate and appropriate assessment of prognosis . - pubmed
The purpose of this study was to identify the prognostic factors and to establish a risk grouping in patients with lung metastases from NPC . - pubmed
METHODS : A total of 198 patients who developed lung metastases from NPC after primary therapy were retrospectively recruited from January 1982 to December 2000 . - pubmed
CONCLUSIONS : In this study , clinical variables provided prognostic indicators of survival in NPC patients with lung metastases . - pubmed
This prospective study evaluated the efficacy and safety of a new formulation , Tamsulosin OCAS ( Oral Controlled Absorption System ) , for LUTS associated with BPH in Thai patients . - pubmed
MATERIALS AND METHODS : Fifty one patients over 40 years old with complaints of LUTS associated with BPH were recruited . - pubmed
At each visit , patients were assessed using the International Prostate Symptom Score ( IPSS ) , Nocturia Quality of Life ( N - QoL ) Questionnaire , QoL Assessment Index ( IPSS - QoL ) , and International Index of Erectile Function ( IIEF ) . - pubmed
Three patients experienced mild dizziness . - pubmed
CONCLUSION : Tamsulosin OCAS treatment led to significant improvements in LUTS , HUS and QoL in Thai patients with bladder outlet obstruction from BPH with few side effects . - pubmed
STUDY DESIGN : Histopathologic and immunohistochemical analysis of the herniated disc specimens obtained from 50 patients who had unilateral persistent radicular pain or unilateral radicular motor paresis . - pubmed
It is well known that spontaneously hypertensive rats ( SHR ) develop muscle pathologies with hypertension and heart failure , though the mechanism remains poorly understood . - pubmed
The hepatitis C virus ( HCV ) causes one of the most prevalent chronic infectious diseases in the world , hepatitis C , which ultimately develops into liver cancer through cirrhosis . - pubmed
CONCLUSION : A significant health disparity exists in the prescribing pattern of epinephrine autoinjectors for peanut - allergic children from families of differing SES . - pubmed
Body composition in lean women with polycystic ovary syndrome : effect of ethinyl estradiol and drospirenone combination . - pubmed
BACKGROUND : Limited data are available regarding the potential effects of oral contraceptives ( OCs ) on body fat distribution particularly in lean women with polycystic ovary syndrome ( PCOS ) . - pubmed
STUDY DESIGN : Participants included 28 lean patients with PCOS and 28 age- and body mass index ( BMI)-matched healthy women . - pubmed
The PCOS patients received ethinyl estradiol 30 mcg / drospirenone 3 mg for 6 months . - pubmed
OC therapy for 6 months in PCOS patients results in an increased total and trunk fat percentage despite no change in clinical anthropometric measures including weight , BMI and WHR . - pubmed
Prodrug of green tea epigallocatechin-3 - gallate ( Pro - EGCG ) as a potent anti - angiogenesis agent for endometriosis in mice . - pubmed
Green tea epigallocatechin-3 - gallate ( EGCG ) can inhibit angiogenesis and development of an experimental endometriosis model in mice , but it suffers from poor bioavailability . - pubmed
In this study , the potential of pro - EGCG as a potent anti - angiogenesis agent for endometriosis in mice was investigated . - pubmed
In conclusion , pro - EGCG significantly inhibited the development , growth and angiogenesis of experimental endometriosis in mice with high efficacy , bioavailability , anti - oxidation and anti - angiogenesis capacities . - pubmed
The objective of the present study was to compare the demographics , risk factors , and clinical outcomes between patients with biliary tract infection caused by ESBL - producing and non - producing Klebsiella pneumoniae and Escherichia coli . - pubmed
METHODS : Between February 2005 and August 2010 , we collected 159 cases with biliary tract infection caused by K. - pubmed
CONCLUSION : ESBL status of bacterial isolates for patients with biliary tract infection caused by K. - pubmed
BACKGROUND : Hydration and anticoagulation are the standard of care for cerebral venous sinus thrombosis ( CVST ) but some patients remain refractory to medical management and warrant more aggressive therapy . - pubmed
OBJECTIVE : Present an alternative technique for endovascular transvenous thrombectomy in a series of CVST patients . - pubmed
METHODS : We reviewed the records of six patients with medically refractory CVST . - pubmed
On imaging , four of the six patients had hemorrhage , edema , and mass effect present before treatment , while two had edema only . - pubmed
OBJECTIVE : : To evaluate if 20 is a possible critical PJK angle in primary adult scoliosis surgery patients as a threshold for worse patient - reported outcomes . - pubmed
METHODS : : Clinical and radiographic data of 90 consecutive primary surgical patients at a single institution ( 2002 - 2007 ) with adult idiopathic / degenerative scoliosis and 2 - year minimum follow - up were analyzed . - pubmed
The patient was a 59 - year - old postmenopausal woman with multiple liver metastases at first examination . - pubmed
The continuation of trastuzumab is considered effective after having progressed by trastuzumab including pretreatment , and we consider it worth while to give a combination of trastuzumab and capecitabine to patients with extensive liver metastases and associated impaired liver function , because of the treatment 's synergistic effect and low risk of causing severe adverse events . - pubmed
Patients had neither cold intolerance nor scar hypersensitivity . - pubmed
ES-62 , an immunomodulator secreted by filarial nematodes , exhibits therapeutic potential in mouse models of allergic inflammation , at least in part by inducing the desensitisation of Fc epsilon RI - mediated mast cell responses . - pubmed
In two of the three patients with ruptured aneurysms , consciousness level on admission was stupor . - pubmed
The main source of infections is beef or greens contaminated with E. - pubmed
Patients with osteogenesis imperfecta , known vitamin D deficiency , and skeletal or metabolic dysplasia were not included in the study . - pubmed
RESULTS : Sixteen infants ( age range 1 - 11 months , seven males and nine females ) with 23 rib fractures were analysed . - pubmed
In pediatric patients biliary atresia and different forms of metabolic liver disorders represent the main indication for liver transplantation . - pubmed
Effects of a 12 - week aerobic training on glycemic control in type 2 diabetes mellitus male patients . - pubmed
Atypical features in a patient with acute promyelocytic leukaemia : a potential diagnostic pitfall . - pubmed
In patients with acute leukaemia , a high index of suspicion is required to exclude APML . - pubmed
Several species of tick - borne rickettsiae that were considered nonpathogenic for decades are now associated with human infections , and novel Rickettsia species of undetermined pathogenicity continue to be detected in or isolated from ticks around the world . - pubmed
Approaches to study yeast cell aging and death . - pubmed
For c. 50 years , yeast has been an established model organism for basic and applied research , and more specifically , for c. 15 years , this unicellular organism has been applied to dissect molecular mechanisms of cell aging and programmed cell death . - pubmed
The study determined the effect of chronic ethanol use on the therapeutic window of d4 T , 3TC and NVP in HIV - infected patients using alcohol - use biomarkers to screen patients for chronic ethanol use . - pubmed
Grading slightly failed to be significantly inversely associated , and survival analysis revealed no significant survival benefit of CD166 - positive patients . - pubmed
Primary resuscitation , debridement , urgent reduction of dislocation , and adequate antibiotic support resulted in good clinical outcome in our patient . - pubmed
CASE PRESENTATION : We describe a case of isolated right ventricular endomyocardial fibrosis in a 27 - year - old Caucasian man from a temperate climate who presented initially with frank hemoptysis and pulmonary thromboembolic disease . - pubmed
CONCLUSIONS : We conclude that endomyocardial fibrosis should be included in the differential diagnosis of apical cardiomyopathies in patients from temperate climates . - pubmed
We retrospectively reviewed the clinical and radiographic results of THA performed in 167 hips for 100 patients with AS . - pubmed
In patients with AS with severe pain , limited motion and posture , as well as deformity , the overall outcomes after THA were found to be favorable with an encouraging midterm prosthetic survivorship , a low complication rate and a high level of patients ' satisfaction . - pubmed
Identification of human papillomavirus status specific biomarker in head and neck cancer . - pubmed
BACKGROUND : In an attempt to improve the prognosis of patients with head and neck cancer , it could be necessary to identify biomarkers in homogeneous subgroups of patients with head and neck cancer . - pubmed
METHODS : We explored the necessity of human papillomavirus ( HPV ) status - specific biomarkers in patients with head and neck cancer and identified an HPV status - specific gene set . - pubmed
RESULTS : The identified gene set for distinguishing head and neck cancer from head and neck normal , did not accurately discriminate the HPV specific patients with head and neck cancer from the head and neck normal group . - pubmed
It is expected that HPV status - specific biomarkers can be helpful in deciding therapeutic methods for patients with head and neck cancer , after biological validation and large prospective trials . - pubmed
Vasopressin Associated With an Increase in Return of Spontaneous Circulation in Acidotic Cardiopulmonary Arrest Patients . - pubmed
OBJECTIVE : Determine if vasopressin therapy in combination with epinephrine was associated with improved outcomes in patients with cardiac arrest compared to epinephrine alone . - pubmed
Patients & gt;=18 years of age with documented cardiac arrest requiring ACLS and vasopressor therapy were included . - pubmed
Subgroup analysis of ROSC in patients with an arterial pH of & lt;7.2 ( n = 35 ) showed an increased rate of ROSC ( 63 % vs 37 % , P = 0.01 ) in the vasopressin plus epinephrine group versus the epinephrine alone group , respectively . - pubmed
CONCLUSIONS : Vasopressin in combination with epinephrine demonstrated improved ROSC in cardiac arrest patients with initial arterial pH & lt;7.2 compared with epinephrine alone , without improving survival to hospital discharge . - pubmed
To confirm the anti - influenza activity of these flavonoids , we used an in vivo mouse model . - pubmed
In mice infected with human influenza , oral administration of 3,4 DHF significantly decreased virus titers and pathological changes in the lung and reduced body weight loss and death . - pubmed
BACKGROUND : The European Carotid Surgery Trial ( ECST ) risk model is a validated tool for predicting cerebrovascular risk in patients with symptomatic carotid disease . - pubmed
Patients were followed up until carotid endarterectomy , recurrent cerebral event , death , or study end . - pubmed
We recently mapped a major OS susceptibility QTL to mouse chromosome 14 by comparing alpha - radiation induced osteosarcoma in mouse strains which differ in their tumor susceptibility . - pubmed
Inflammation has a key role in the pathogenesis of various human diseases . - pubmed
Whereas most deletion strains had no detectable difference in growth compared to wild - type yeast , two - thirds of deletion strains had alterations in metabolic profiles . - pubmed
METHOD : A group of 210 adult middle - class Mexican non - diabetic obese patients was evaluated : 105 normal weight individuals , and 105 non - diabetic obese . - pubmed
Microscopic images are acquired from blood and bone marrow smears of patients with Acute lymphoblastic leukemia and normal cases . - pubmed
Phthalates are a group of synthetic compounds mainly used as plasticizers , which have been classified as endocrine - disrupting chemicals and potential human - cancer causing agents . - pubmed
Systolic murmur in a young man who had previous ventricular septal defect repair : the double - chambered right ventricle . - pubmed
MATERIALS AND METHODS : The ultrasound appearances of ten histologically proven subcutaneous IPEH in ten patients ( age range , 15 - 69 years ; mean age , 38.2 years ; six females , four males ) were reviewed retrospectively by two musculoskeletal radiologists . - pubmed
Risk of lower extremity arterial disease in a cohort of workers occupationally exposed to ionizing radiation over a prolonged period . - pubmed
In this study the incidence risk of lower extremity arterial disease ( LEAD ; international classification of diseases version 9 code 440.2 ) was assessed in a cohort of workers occupationally exposed to radiation over a prolonged period . - pubmed
CONCLUSION : Our PEGylated liposome formulation reported in this study could potentially produce viable clinical strategies for improved delivery of DOC for the treatment of human cancer . - pubmed
Translational Pharmacokinetic - Pharmacodynamic Modeling and Simulation : Optimizing 5 - Fluorouracil Dosing in Children With Pediatric Ependymoma . - pubmed
To select a 5 - FU dosage for our clinical trial in children with ependymoma , we simulated various 5 - FU dosages for tumor exposures and tumor growth inhibition , as well as considering tolerability to bolus 5 - FU administration . - pubmed
We developed a pediatric population PK model of bolus 5 - FU and simulated tumor exposures for our patients . - pubmed
Simulations for tumor concentrations indicated that all patients would be above the 1 - hour target exposure for antitumor effect . - pubmed
In this study , we compared the in vitro cytotoxicity of CuO NPs of two distinct sizes ( 4 and 24 nm ) using the A549 human lung cell line . - pubmed
We report on a 68 - year old patient who developed necrotizing fasciitis of the right elbow with multiorgan failure and long - term ventilation after an accidental and minor injury . - pubmed
Local recurrence was observed in 9 patients and distant metastases in 15 patients . - pubmed
Tumors that were & gt;=3 cm in maximal dimension were associated with a worse overall survival and patients with neoadjuvant radiation were at increased risk of complications . - pubmed
Type 2 diabetes was induced in rats by high fructose - high fat diet and low streptozotocin dose . - pubmed
In addition , 4 - AB administration improved the elevated blood pressure and the associated exaggerated vascular contractility , endothelial destruction and vascular inflammation seen in diabetic animals . - pubmed
We found that Mo POM nanoparticles , especially complex 3 , inhibited the growth of human hepatocellular liver carcinoma cells ( HepG2 ) through cellular reactive oxygen species levels ' elevation and mitochondrial membrane potential damage . - pubmed
Finally , as proof of concept , the method was applied to human kidney tissue where a clear differentiation between kidney cancer and nontumorous material could be demonstrated on the basis of unsupervised statistical analysis . - pubmed
Valproate Reduces Delayed Brain Injury in a Rat Model of Subarachnoid Hemorrhage . - pubmed
We tested whether SD - inhibitor valproate reduces brain injury in an SAH rat model with and without experimental SD induction . - pubmed
CONCLUSIONS : In our rat SAH model , valproate treatment significantly reduced brain lesion growth after KCl application . - pubmed
In the present case study , a 27 - year - old woman with a large myxoma originating from the left ventricular free wall is studied . - pubmed
Several of the same agents alter metabolic function in human cells and are associated with human obesity or metabolic dysfunction in humans . - pubmed
We address the evidence for a role in the genesis of obesity for viral agents in five broad categories : adenoviridae , herpesviridae , phages , transmissible spongiform encephalopathies ( slow virus ) , and other encephalitides and hepatitides . - pubmed
This approach will serve as the basis for the development of oral plant - based vaccines against PD with several potential advantages such as low cost , easy scale - up during production , and easy administration . - pubmed
Rechallenge to Carboplatin in Children with Low Grade Glioma and Carboplatin Hypersensitivity Reactions . - pubmed
Background : Carboplatin based regimens have demonstrated activity in pediatric patients with low grade gliomas ( LGG ) . - pubmed
Methods : We performed a retrospective review of children with LGG treated between January 1994 and July 2015 with carboplatin and vincristine who had a documented CHR . - pubmed
Hypersensitivity reactions occurred in 6 patients ( 20.7 % ) of the first , and 10 patients ( 55.5 % ) of the second group , respectively . - pubmed
Pasteurella multocida meningoencephalitis in an immunocompetent adult with multiple cat scratches . - pubmed
P multocida is a Gram - negative coccobacillus which frequently colonises the nasopharynx of animals ; it is a recognised but very rare cause of meningoencephalitis in immunocompetent adults . - pubmed
Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis . - pubmed
To better understand the lesional biology of TB infection , we digitally barcoded M. - pubmed
Hydrogen peroxide and nitric oxide regulation of phenolic metabolism under water stress and ABA in wheat . - pubmed
[ Effects of seawater immersion on the inflammatory response and oxygen free radical injury of rats with superficial partial - thickness scald at early stage ] . - pubmed
Objective : To study the effects of seawater immersion on the inflammatory response and oxygen free radical injury of rats with superficial - thickness scald at early stage . - pubmed
Conclusions : Seawater immersion can enhance the inflammatory response and oxygen free radical injury of wounds and the whole body of rats with superficial partial - thickness scald at early stage . - pubmed
Human emotions , such as anxiety , depression , fear , joy , and laughter , profoundly affect psychological and physiological processes . - pubmed
We aimed to determine the impact of soy on cardiometabolic health , adipose tissue inflammation , and the cecal microbiota in ovariectomized ( OVX ) rats bred for low - running capacity ( LCR ) , a model that has been previously shown to mimic human menopause compared to sham - operated ( SHM ) intact control LCR rats . - pubmed
Furthermore , soy significantly improved blood lipid profile , adipose tissue inflammation , and aortic stiffness of LCR rats . - pubmed
Cabazitaxel in the treatment of metastatic castration - resistant prostate cancer : patient selection and special considerations . - pubmed
Clinicians must familiarize themselves with the most recent studies as well as drug toxicities to determine the best treatment option for their patients . - pubmed
MATERIAL AND METHODS : Pregnant women ( n=74 ; 30 [ 23 - 38 ] years ) were consecutively recruited from the district of Warsaw , Poland , and divided into healthy subjects ( HS , n=45 ) , and women with a diagnosis of AITD ( AITD , n=29 ) . - pubmed
Forty drug - naive patients with mild cognitive impairment or mild dementia with evidence of amyloid deposition are 1:1 randomized to receive either the multinutrient combination or placebo once daily . - pubmed
METHODS : The medical records of consecutive patients with basic horizontal strabismus who underwent a rectus muscle plication or resection combined with a known amount of antagonist muscle recession from January 2009 - June 2016 by one surgeon were reviewed retrospectively . - pubmed
RESULTS : A total of 162 patients with basic esotropia ( 88 lateral rectus muscle plications ; 74 lateral rectus resections ) and 60 patients with basic exotropia ( 31 medial rectus muscle plications ; 29 medial rectus resections ) were included . - pubmed
No significant differences were found when analyzing the change in ocular alignment between the plication and resection groups for patients with either basic esotropia or basic exotropia . - pubmed
METHODS : Consecutive patients with LSTs 3 cm or larger were enrolled for from May 2010 - 2016 . - pubmed
CONCLUSIONS : ESD appears to be an effective and safe method for LSTs larger than 3 cm in older patients . - pubmed
Mice bearing established subcutaneous tumors were studied . - pubmed
In contrast , VV.CXCL11 increased the number of total and antigen - specific T cells within tumors after CAR T cell injection or vaccination and significantly enhanced anti - tumor efficacy . - pubmed
METHODS : Vaginal pH was determined using standard pH paper strips in two clinical trials involving postmenopausal women with signs and symptoms of VVA evaluated before and after intervention with vaginal estradiol in softgel capsules . - pubmed
The primary tumor site was colorectal in 76 , kidney in 14 , head and neck in 13 , breast in 12 , stomach in 8 , urinary tract in 7 , and other organs in 12 patients . - pubmed
RESULTS : 11,553 trauma patients were admitted , 596 patients ( 5.2 % ) died . - pubmed
These results suggest that measuring the Trp / Kyn ratio may be useful for evaluating immunological status during endocrine therapy in elderly patients with locally advanced breast cancer . - pubmed
The obtained results showed that the cytotoxicity differed according to the used extract with an efficient effect of Cotula cinerea extracts compared to Salvia verbenaca . - pubmed
A potent cytotoxicity was thus observed for the Cotula cinerea hexane extract which inhibited the growth of RD cell line at the lowest IC50 value ( 57.21 + -3.43 microg / mL ) . - pubmed
The results of this study showed thus that Cotula cinerea essential oil and hexane extract showed significant cytotoxic effects against RD and Vero cell lines , respectively , and could be considered as novel source of antitumor agents . - pubmed
This study is expected to be beneficial for clinical and traditional applications for Cotula cinerea as a remedy against cancer and opens new perspectives for further investigations on other types of cancer cell lines . - pubmed
The reconstruction of neo - tongue with vastus lateralis myofascial free flap may be represent a valid surgery for patients with cancer tongue . - pubmed
STUDY SAMPLE : 417 consecutive patients seeking treatment for tinnitus in an Audiology Department in the UK . - pubmed
This case highlights the importance of the utility of bedside ultrasound in patients presenting to the ED with flank pain or abdominal pain which can lead to expedited assessment and appropriate management . - pubmed
As chemo - radiotherapy continues to increase the lifespan of patients with nasopharyngeal carcinoma ( NPC ) , adverse reaction and drug resistance remain two major problems when using cisplatin ( CDDP ) . - pubmed
Annually , the prevalence of low back pain in the general US adult population is 10 - 30 % , and the lifetime prevalence of US adults is as high as 65 - 80 % . - pubmed
Survival outcomes for patients with glioblastoma ( GBM ) are universally poor with only a small percentage of patients surviving five years beyond initial diagnosis . - pubmed
Following tumor resection , the patient underwent concomitant radiation and temozolomide therapy that was complicated by CMV colitis and abdominal abscesses . - pubmed
Despite not receiving adjuvant temozolomide , the patient demonstrated a five year progression - free survival before requiring re - resection for radiation necrosis . - pubmed
We report an unusual case of loss of psychic self - activation appeared immediately after a cardiac arrest in a middle age patient . - pubmed
Two years later , although the cognitive performances of our patient were improved , a second brain MRI demonstrated bilateral pallidal lesions , suggesting a possible mechanism with delayed hypoxic lesions . - pubmed
Phylogeography of Potamon ibericum ( Brachyura : Potamidae ) identifies Quaternary glacial refugia within the Caucasus biodiversity hot spot . - pubmed
We studied phylogeography of Potamon ibericum ( Brachyura : Potamidae ) in the drainages of the western Caucasus biodiversity hot spot ( i.e. - pubmed
In our study , we aimed to compare the effects of perioperative peritonsillar dexamethasone - bupivacaine and bupivacaine - alone infiltration on pain control in pediatric patients . - pubmed
Patients with pain score & gt;= 4 were treated with paracetamol rescue analgesia . - pubmed
A 38 - year - old man presented with an acute onset of pain and swelling of the right testis . - pubmed
The dose- and time - dependent glomerulopathy with progression to chronic progressive nephropathy in female rats appears to be a direct effect of avagacestat and was not ameliorated with co - administration of 17beta - estradiol or an antihypertensive ( enalapril ) and was not present in control OVX rats . - pubmed
In this study , we identified a cardiac endothelial - enriched lncRNA - lnc000908 , which was markedly up - regulated in rats with cardiac fibrosis . - pubmed
We hypothesize that polymorphisms in the same gene may increase a patient 's risk of developing hepatotoxicity when receiving potentially hepatotoxic agents during chemotherapy . - pubmed
Establishment and characterization of a new patient - derived anaplastic thyroid cancer cell line ( C3948 ) , obtained through fine - needle aspiration cytology . - pubmed
Here we describe the establishment and characterization of a new patient - derived cell line , obtained from an unresectable ATC through fine - needle aspiration cytology ( FNAC ) . - pubmed
Metabolic and Inflammatory Effects of an omega-3 Fatty Acid - Based Eucaloric Ketogenic Diet in Mice With Endotoxemia . - pubmed
BACKGROUND : Dietary strategies can aid in the management of critically ill patients . - pubmed
We aimed to determine the effects of a eucaloric ketogenic diet ( EKD ) enriched with omega-3 fatty acids ( O3KD ) on glucose levels and inflammation in mice with endotoxemia . - pubmed
CONCLUSION : An O3KD leads to reduced inflammation and maintains glucose homeostasis in mice with endotoxemia . - pubmed
Salivary FRAP as A Marker of Chronic Kidney Disease Progression in Children . - pubmed
The study included 30 children with CKD and a control group matched by age and gender . - pubmed
We demonstrated that total FRAP , FRAP - UA and UA were significantly higher in stimulated saliva , as well as urine of CKD patients compared to the controls . - pubmed
Interestingly , salivary FRAP and uric acid clearly differentiate between various stages of CKD as well as between healthy and ill children . - pubmed
Although salivary FRAP may be a potential CKD biomarker in children , further studies are needed in a larger group of patients . - pubmed
Primary visual cortical thickness in correlation with visual field defects in patients with pituitary macroadenomas : a structural 7 - Tesla retinotopic analysis . - pubmed
Growing evidence suggests secondary damage to remote visual structures may contribute to vision loss in patients with chiasmatic compression . - pubmed
METHODS : Eight patients ( 4 males and 4 females , mean age 44.3 years ) with pituitary adenomas who exhibited chiasmatic compression and visual field defects , as well as 8 matched healthy controls ( 4 males and 4 females , mean age 43.3 years ) , were scanned at 7 - T MRI for this prospective study . - pubmed
Patients with adenoma additionally underwent neuroophthalmological examination including 24 - 2 Humphrey automated visual field perimetry . - pubmed
These results further characterize changes in the posterior visual pathway associated with chiasmatic compression , and may prove useful in the neuroophthalmological workup for patients with pituitary macroadenoma . - pubmed
METHODS : We performed a retrospective study from 2 institutions of patients with intracranial aneurysms who underwent treatment with WEB device alone or in conjunction with stenting and/or coiling in an off - labeled location . - pubmed
RESULTS : Eleven patients with 12 aneurysms were included . - pubmed
Effects of soft tissue surgery on transverse kinematics in patients with cerebral palsy . - pubmed
BACKGROUND : Gait disturbances , including flexed knee gait , stiff knee gait , and tip - toeing gait , are common in patients with cerebral palsy ( CP ) . - pubmed
CONCLUSIONS : This study found that the transverse kinematics were improved to a more external angle after soft tissue surgery in patients with CP . - pubmed
Therefore , clinicians should consider that soft tissue surgery can affect the transverse plane kinematics in patients with CP . - pubmed
To confirm our findings , further research regarding the natural history of femoral and tibial torsion in children with CP is needed . - pubmed
Background : Xerostomia occurs in the majority of patients undergoing chemoradiation therapy for head and neck cancer ( HNC ) . - pubmed
Materials and Methods : This single - center randomized study was conducted in 30 patients treated with radiotherapy with or without chemotherapy for HNC between 2014 and 2017 , who had at least grade 1 or 2 symptomatic dry mouth ( xerostomia ) according to CTEP NCI Common Terminology Criteria for Adverse Events ( CTCAE version 4.0 ) . - pubmed
A 19 - Year - Old Man With Vaping - Associated Lung Injury . - pubmed
Clinical guidelines from the United States and Europe do not recommend treatment with statins for primary prevention in patients with hypercholesterolemia who are older than 75 years . - pubmed
Silver - coated zero - valent iron nanoparticles enhance cancer therapy in mice through lysosome - dependent dual programed cell death pathways : triggering simultaneous apoptosis and autophagy only in cancerous cells . - pubmed
In the xenograft mouse model , cancer growth was significantly inhibited by a single dose of systematically administered NPs without significant weight loss in animals . - pubmed
Among the double co - infections , those of E. - pubmed
Coenzyme Q10 supplementation of human oocyte in vitro maturation reduces postmeiotic aneuploidies . - pubmed
OBJECTIVE : To evaluate the effect of coenzyme Q10 ( CoQ10 ) supplementation on oocyte maturation rates and postmeiotic aneuploidy rates during in vitro maturation ( IVM ) of human oocytes . - pubmed
RESULT(S ): In women aged 38 - 46 years , 50 mumol / L CoQ10 significantly increased oocyte maturation rates ( 82.6 % vs. 63.0 % ; P=.035 ) , reduced oocyte aneuploidy rates ( 36.8 % vs. 65.5 % ; P=.020 ) , and reduced chromosome aneuploidy frequencies ( 4.1 % vs. 7.0 % ; P=.012 . - pubmed
Enhancing of anthracnose disease resistance indicates a potential role of antimicrobial peptide genes in cassava . - pubmed
Cassava anthracnose disease , caused by Colletotrichum gloeosporioides f.sp . - pubmed
To minimize the effects of such disease , this study investigated the response of cassava to attack by CAD and how the plants defend themselves against this threat . - pubmed
Differential expression profiles of six candidate genes were observed in response to CAD infection of both cassava cultivars . - pubmed
The patient is a 22 - year - old female with a history of a posterior fossa medulloblastoma diagnosed 8 years prior for which she underwent surgical resection followed by adjuvant chemotherapy and craniospinal radiation . - pubmed
Functional network connectivity ( FC ) and long - term potentiation ( LTP ) , considered as the plasticity substrate of learning and memory , were longitudinally assessed in mice of the P301S model of tauopathy following the course ( time and location ) of progressively neurodegenerative pathology ( i.e. - pubmed
Oxidized Zirconium Total Knee Arthroplasty Implant Failure in a Patient With Knee Instability . - pubmed
We report a case of an oxidized zirconium total knee arthroplasty failure in a patient with knee instability . - pubmed
Though honokiol , derived from the Magnolia tree , was known to suppress renal fibrosis , pulmonary fibrosis , non - alcoholic steatoheptitis , inflammation and cancers , the underlying antifibrotic mechanisms of honokiol are not fully understood in hepatic stellate cells until now . - pubmed
In this study , we sought to build a machine learning model for predicting LVR in AMI patients after effective percutaneous coronary intervention ( PCI ) that contains the majority of the clinical risk factors and compare 3D STE parameters values for LVR prediction . - pubmed
We enrolled 135 first - onset AMI patients ( 120 males , mean age 54 + - 9 years ) . - pubmed
This study compared the NLR , PLR , and MLR values in the manic and euthymic phases of the same patients . - pubmed
METHODS : Patients who met the inclusion criteria and were hospitalized due to bipolar affective disorder manic episodes at the Ondokuz Mayis University Faculty of Medicine inpatient psychiatry clinic between 01.01.2013 and 01.01.2019 were enrolled in the study . - pubmed
One hundred thirteen patients undergoing manic episodes were included . - pubmed
Complications rate of and risk factors for the unplanned reoperation of degenerative lumbar spondylolisthesis in elderly patients : a retrospective single - Centre cohort study of 33 patients . - pubmed
English full - text studies that included human subjects experiencing a cutaneous reaction comprising granulomatous inflammation as the direct result of a drug were included . - pubmed
Adult mammalian cardiomyocytes ( CM ) are postmitotic , differentiated cells that can not re - enter the cell cycle after any appreciable injury . - pubmed
CASE REPORT : A 49 - year - old woman presented to our Emergency Department ( ED ) with a complaint of epigastric pain radiating to the left shoulder . - pubmed
Peripheral - nerve lipid abnormalities in patients on perhexiline maleate . - pubmed
Putrescine and spermidine in the cyst coat of the protozoan Colpoda steinii [ proceedings ] . - pubmed
Recovery from monocular stimulus deprivation amblyopia in the kitten . - pubmed
A review of experimental studies on recovery from monocular stimulus deprivation amblyopia in the kitten is presented . - pubmed
The conclusions drawn from these experimental studies of monocular deprivation suggest a possible approach to the treatment of human amblyopia . - pubmed
Although situated in a holoendemic region with constant human movements in and out of the town , the mining company has succeeded in controlling malaria in Yekepa . - pubmed
The dominant malaria parasite in the area was Plasmodium falciparum . - pubmed
At each tolbutamide dose level the mean IRI response of obese subjects was about three times greater than in controls . - pubmed
In acromegalic subjects an increased response was observed only after the 200 mg dose of tolbutamide . - pubmed
There were seven patients during pregnancy and eight after delivery who required hospitalization and treatment for congestive heart failure . - pubmed
Five of the patients were not given anticoagulation therapy , but when thromboembolism developed , warfarin was administered . - pubmed
In the first two groups , four patients had episodes of thromboembolism . - pubmed
Man and many other animals have mobilizing mechanisms for preparation for physical activity , expressed inter alia by an increase in blood pressure , hyperglycaemia and hyperlipidaemia . - pubmed
The clinical significance of the disturbance in magnesium metabolism is discussed on results of two groups of patients with hyperthyroidism . - pubmed
One group of 7 patients with high serum thyroxine levels and mild clinical signs of thyrotoxicosis showed a normal magnesium concentration in serum . - pubmed
A patient with a newly recognised variant of biotinidase deficiency presented with acute bilateral visual loss at the age of 10 years . - pubmed
The patient no longer has back pains , and no signs of bone metastases were seen on both scintigrams for two years and eight months from December 1988 to August 1991 . - pubmed
It is expected that the successfully treated patients even with bone metastasis will be increasingly reported from now as various new approaches including induced hypertension chemotherapy are introduced . - pubmed
In 19 patients with closed - loop intestinal obstruction , including 16 patients with strangulating obstruction , the findings at examination with computed tomography ( CT ) were retrospectively correlated with the surgical and pathologic findings and evaluated by two radiologists . - pubmed
Fever was a presenting sign in 8 of 11 patients , whereas all 4 patients who presented with back pain had nontuberculous lumbar osteomyelitis or disk space infections . - pubmed
Elderly patients , diabetics , and patients with chronic disease are susceptible to this kind of occult infection and may present with minimal clinical findings . - pubmed
Verapamil prevents slowing of transmural conduction and suppresses arrhythmias in an isolated guinea pig ventricular model of ischemia and reperfusion . - pubmed
This procedure has been applied to patients with keratoconus , myopia , and aphakia . - pubmed
Several large studies of epikeratoplasty have been conducted which suggest that the procedure be limited to keratoconus and aphakic patients who are contact and spectacle lens intolerant . - pubmed
One or more adverse sequelae were present in 11 ( 22 % ) obese and in 9 ( 18 % ) of non - obese women , proportions not significantly different . - pubmed
Plasma zinc levels were measured in 14 patients with primary affective disorder on admission to hospital ; they were compared with plasma zinc levels in group of 14 age- and sex - matched controls . - pubmed
Plasma zinc levels of 9 of the depressed patients on admission to hospital and at the point of discharge were compared ; a significant increase in zinc levels was detected . - pubmed
In the other two patients with SVC syndrome , a trans - sternal surgical approach was applied in order to resect a large tumor extending into the anterior mediastinum . - pubmed
Combination chemotherapy for patients with advanced carcinoma of the cervix : trial of mitomycin - C , vincristine , bleomycin , and cisplatin . - pubmed
Sixteen patients with metastatic or recurrent carcinoma of the cervix were treated with combination chemotherapy consisting of mitomycin - C , vincristine , bleomycin , and cisplatin . - pubmed
Ultrastructure of capillary walls in human brain tumors . - pubmed
Changes in capillary walls between human glial , non - glial and metastatic brain tumors were studied with conventional ultrathin section and freeze - fracture replica techniques . - pubmed
To further define the clinicopathologic features and determinants of survival , we reviewed the cases of 110 patients with primary hepatic malignancy managed surgically between 1975 and 1986 . - pubmed
Intermittent shock titration task in the rhesus monkey and its validity as an analgesiometric procedure . - pubmed
The case for treating women at high risk of breast cancer with the anti - oestrogen tamoxifen is presented . - pubmed
Thymic lymphomas appeared with a short latent period of 4 - 5 weeks in BALB / c mice and 8 weeks in C57BL/6 mice . - pubmed
Authors present two cases of thyroid carcinoma in female patients ages 6 and 7 years with a two month evolution before diagnosis . - pubmed
The ESR before the exchange arthroplasty averaged 53 mm / h. ESR values at 6 weeks , 3 and 6 months after the exchange operation were lower in 60 patients in whom the infection healed than in 16 patients whose infection had not healed . - pubmed
Establishment of six human pancreatic cancer cell lines and their sensitivities to anti - tumor drugs . - pubmed
Six human pancreatic cancer cell lines PK-1 , - 8 , -9 , -12 , -14 and -16 , were established . - pubmed
They originated from either primary pancreatic cancer biopsy or liver metastasis biopsy , or xenografts of these biopsy specimens in athymic nude mice . - pubmed
Active defence of retinal temperature during hypothermia of the eye in cats . - pubmed
Sixty - one women with a past history of elevated blood pressure ( high - risk group ) associated with oral contraceptive use ( 27 patients ) , unknown etiology ( 17 patients ) , or preeclampsia ( 17 patients ) used a low - dose oral contraceptive containing 0.4 mg of norethindrone and 35 micrograms of ethinyl estradiol for 3 to 24 months . - pubmed
Sixty - one women without a past history of elevated blood pressure ( low - risk group ) , selected from a pool of 616 low - risk patients , were matched with the high - risk group for race , initial age , initial body weight , duration of use , history of smoking , and family history of hypertension . - pubmed
Five high - risk patients ( 8.2 % ) discontinued therapy because of the redevelopment of hypertension ; however , blood pressures at discontinuance were comparable to the previous highest blood pressures . - pubmed
Distribution of pneumococcus - induced augmentation of tissue leukostasis in rabbits : specificity for the pulmonary vascular bed . - pubmed
We studied whether pneumococcal ( PNC ) sonicate - induced leukostasis is specific for the lung or whether it occurs in extrapulmonary foci as well . - pubmed
[ LINAC radiation effect on human glioma and glial cells ] . - pubmed
Ultrastructure of the " cyst - like bodies " of Trypanosoma conorhini . - pubmed
[ Therapy with gentamicin in patients operated for heart diseases . - pubmed
Deletion , monosomy , and multiple monosomy - trisomy mosaicism in chicken embryos . - pubmed
[ Frequency of double pre - beta bands during electrophoresis on membrane foil of lipids from patients with vascular diseases ] . - pubmed
Clinical diagnoses included cellulitis ( 39 patients ) , abscesses ( 14 ) , infected ulcers ( 3 ) , and bursitis ( 1 ) . - pubmed
Effect of exercise training on the blood pressure and hemodynamic features of hypertensive adolescents . - pubmed
When the subjects were retested 9 + /- 1 months after cessation of training , systolic BP and VO2 max had returned to pretraining levels ; however , diastolic BP was still below pretraining levels in the subjects who had diastolic hypertension initially . - pubmed
These data indicate that moderate endurance exercise training can lower BP in otherwise healthy hypertensive adolescents as an initial therapeutic intervention . - pubmed
Clinical experiences with oxyfedrine in patients with angina pectoris . - pubmed
This adoptive transfer was studied in an inbred strain of syrian hamsters . - pubmed
The influence of aorto - coronary bypass surgery ( ACBS ) on ventricular arrhythmia was examined in 57 patients . - pubmed
Complex PVCs were present in 8 patients preoperatively and in 9 patients after ACBS . - pubmed
To determine whether or not changes in renal gluconeogenesis in vivo were accompanied by altered renal handling of phosphate , possibly related to NAD + action on BBM phosphate transport in vivo , renal gluconeogenesis was stimulated in rats by metabolic acidosis . - pubmed
Chronic acidosis in rats previously adapted to low phosphorus diet was associated with increased UPiV ( controls , 68 + /- 19 ; acidotic , 1055 + /- 428 nmoles / mg creatinine ; P less than 0.05 ) without changes in plasma phosphate and creatinine ( Cr ) and in UCrV compared to controls . - pubmed
Decreased BBM transport of phosphate in proximal tubules of acidotic rats may explain the increased UPiV. - pubmed
[ Gastric stasis induced by stress in the rat : its reversal by clebopride ] . - pubmed
Hepatobiliary functional scintigraphy ( HBFS ) using 99 m Tc - labeled Diethyl - IDA was tested in 84 patients suffering from various hepatic and bile duct disorders . - pubmed
Ninety - nine hypertensive patients who had been on antihypertensive therapies for at least six months because of diastolic blood pressure of 105 mg Hg or more were interviewed immediately after seeing their physicians . - pubmed
The carriage on skin lesions , on healthy skin and in the nose , of micro - organisms that produce antibiotics active against Staphylococcus aureus has been studied . - pubmed
No evidence could be found that the presence of producer organisms in skin lesions had a protective effect against colonisation by S. - pubmed
A correlation with the toxicity observed in other species is developed by establishing the effect of a prototype compound for each toxicity and tests of one or more compounds expected to lack such toxicity . - pubmed
Open label trial with vigabatrin in children with intractable epilepsy . - pubmed
Thirty children ( 20 males , 10 females ) with intractable epilepsy received vigabatrin ( VGB ) as an open label basis to preexisting antiepileptic drugs . - pubmed
The result of treatment was categorized as ' responders ' with 13 ( 43 % ) having 50 - 75 % reduction of seizure frequency ; and ' non - responders ' which consisted of 17 children . - pubmed
[ Suture material and suturing of the laparotomy wound in horses and cattle ] . - pubmed
To study the prevalence of insulin resistance in patients with polycystic ovary syndrome ( PCO ) and the correlation between hyperinsulinemia and hyperandrogenism , 48 patients were divided into four groups : group 1 , non - obese ovulatory women ( n = 10 ) ; group 2 , obese ovulatory women ( n = 9 ) ; group 3 , non - obese women with PCO ( n = 14 ) ; group 4 , obese women with PCO ( n = 15 ) . - pubmed
There was also a high prevalence of insulin resistance in patients with PCO regardless of obesity , and hyperandrogenism - aggravated insulin resistance . - pubmed
By conducting electrophysiological tests on patients with facial nerve paralysis , the characteristics of synkinesis and the mechanisms of its manifestations were examined . - pubmed
The subjects were 114 patients of facial nerve paralysis on whom electroneurography ( ENoG ) and the blink reflex were conducted . - pubmed
The authors describe a case of symptomatic cranial settling in a nonrheumatoid patient with chronic , severe , spasmodic torticollis resulting in erosive changes in the occipito - atlanto - axial complex . - pubmed
RESULTS : There was a significant difference not only between tumor sizes of 2 cm or larger and those of less than 2 cm ( p & lt ; 0.001 ) , but also between patients with lymph node metastasis and patients free from it ( p & lt ; 0.001 ) . - pubmed
Because , in vitro , PMNs from patients with UC appear normal and are not therefore a likely cause for the enhancements , we hypothesized an abnormal colonic milieu . - pubmed
Using rectal dialysis , we sampled the colonic milieu in patients with active UC , in patients with inactive UC , and in control subjects . - pubmed
Blood monocytes from healthy donors and breast cancer patients as well as tissue macrophages from patients with fibrocystic changes of the breast were also examined . - pubmed
BACKGROUND : Flutamide withdrawal has been reported to benefit patients with hormone - refractory prostate cancer . - pubmed
METHODS : Sixteen patients with hormone - refractory prostate cancer were enrolled in the study . - pubmed
The time to cancer progression for these 8 patients was 2 to 15 months ( mean , 4 months ) . - pubmed
To test this , normal melanocyte lines ( melan - a and C57 M ) of C57BL/6 mice were infected with the MelARV produced by B16BL6 melanoma . - pubmed
Two infected melanocyte sublines showed morphological changes , were able to grow in the absence of TPA and , after inoculation into C57BL / 6 mice , produced rapidly growing , highly pigmented tumors . - pubmed
Thus , our data imply that the ecotropic MelARV that somatically emerged in B16 and other melanomas of C57BL/6 mice may play a role in malignant transformation . - pubmed
Thirteen asthmatic patients ( 29 + /- 15 years , 4 men and 9 women ) were randomly assigned to receive one nebulization of each of the three treatment regimens at 24 h interval . - pubmed
PATIENTS AND METHODS : Patients with inoperable or metastatic colorectal cancer were randomized to receive monthly FU 400 mg / m2 / day plus LV 20 mg / m2 / day as intravenous push daily for five days , or FU alone . - pubmed
RESULTS : Clinical trials of UFT published in the Western world have included 581 patients with colorectal cancer . - pubmed
These diseases include Crohn disease , ischemic colitis , intestinal Behcet disease , Enterohemorrhagic E. - pubmed
coli including O157 , antibiotics associated hemorrhagic colitis and so on . - pubmed
Possible immunologic interaction between infection with human T lymphotropic virus type 1 ( HTLV-1 ) , a retrovirus , and the intestinal parasite Strongyloides stercoralis was investigated in persons infected with one or both agents . - pubmed
BACKGROUND : Population - based data are unavailable concerning the predictive value of orthostatic hypotension on mortality in ambulatory elderly patients , particularly minority groups . - pubmed
Adenoid cystic carcinoma of the lacrimal gland simulating a dermoid cyst in a 9 - year - old boy . - pubmed
Adenoid cystic carcinoma of the lacrimal gland is a malignant neoplasm that is generally found in adults and is usually managed by orbital exenteration and supplemental external beam irradiation or chemotherapy . - pubmed
A recent report has suggested that the tumor may have a less malignant course in children . - pubmed
We describe a case of adenoid cystic carcinoma of the lacrimal gland that simulated a dermoid cyst clinically and radiographically in a 9 - year - old boy . - pubmed
Although no prognostic conclusions can be drawn on the basis of a single case report with short follow - up , the relatively earlier detection of this tumor made possible by modern orbital imaging studies may allow total removal at an earlier stage and prevent orbital exenteration in a patient with normal vision . - pubmed
Pneumocystis carinii remains an important cause of pneumonia in immunocompromised patients , particularly in those who have acquired immune deficiency syndrome . - pubmed
Oncogenes , tumor - suppressor genes , and cell - survival genes have all been found to be dysregulated in some myeloma patients . - pubmed
Pamidronate , a second - generation bisphosponate , has been shown to be effective at decreasing adverse skeletal events in patients with advanced myeloma . - pubmed
Through such injuries , workers risk infection ( the average infection risk from injuries is 1 in 300 ) with deadly diseases such as Hepatitis B or C , or HIV , the virus that causes AIDS . - pubmed
Similarities between ileal Crohn ' s disease and indomethacin experimental jejunal ulcers in the rat . - pubmed
BACKGROUND : Both Crohn ' s disease ileal ulcers and indomethacin - induced jejunal ulcers in the rat have a predilection for the mesenteric margin of the bowel wall . - pubmed
METHODS : Ileal Crohn ' s disease ulcers identified in surgical resection specimens ( n=5 ) and indomethacin - induced lesions in the rat jejunum ( n=6 ) were examined macroscopically and histologically . - pubmed
RESULTS : In both the human ileum and the rat jejunum , ulcers occurred consistently along the mesenteric margin , with the most extensive mucosal injury occurring at two adjacent sites on either side of the midline of this margin . - pubmed
CONCLUSIONS : For anatomical reasons apparently related to the vasculature of the human and rodent small bowel , specific sites along the mesenteric margin are susceptible to Crohn ' s disease ulceration and NSAID damage , respectively . - pubmed
Renal handling of zinc in insulin - dependent diabetes mellitus patients . - pubmed
Hyperzincuria is a common feature in diabetic patients , which is still not understood . - pubmed
Based on the above consideration , the aim of the present study was to investigate the renal handling of zinc in insulin - dependent diabetes mellitus ( IDDM ) patients . - pubmed
About 10 % of all patients develop secondary MDS / leukemia . - pubmed
This seems to be one important step in leukemogenesis in CN patients . - pubmed
METHOD : A patient suffering from Wolff - Parkinson - White syndrome was investigated prior the catheter ablation . - pubmed
bulgaricus 2038 , yogurt starters , were chosen as test - strains , and ether extracts of these cultures were used as samples . - pubmed
112 patients ( 17 men , 95 women , mean age 46.5 + /- 3.8 ) with various thyroid diseases were examined . - pubmed
Benign diseases were revealed in 96 ( 85.7 % ) patients , thyroid cancer -- in 16 ( 14.3 % ) . - pubmed
, Pantoea agglomerans , Citrobacter freundii and Serratia marcescens strains isolated from children between 0 and 3 years of age is presented . - pubmed
METHODS : Bilateral 3 - wall intrabony periodontal defects were surgically induced in the premolar region in the maxilla and mandible in 8 young adult Korean mongrel dogs . - pubmed
Bone marrow cytogenetic complete remission achieved by interferon - alpha plus cytarabine ocfosfate therapy in a patient with chronic myelogenous leukemia during extramedullary blast crisis . - pubmed
We report herein the case of a 67 - year - old man who was admitted to our hospital with a 3 - month history of hoarseness , a cervical mass , and weak muscles of the extremities 6 years after undergoing a right colectomy for carcinoma . - pubmed
The patient eventually died from the malignancy , although he survived for 4 months after the disclosure of the metastases . - pubmed
All patients received a low molecular weight heparin as a prophylaxis for deep venous thrombosis . - pubmed
Patients operated on the day of admission had more bleeding complications than those who were operated on the day after admission ( 19/145 ( 13 % ) compared with 4/61 ( 7 % ) ) . - pubmed
Smoking and use of antihypertensive medication were registered more often in patients without bleeding complications . - pubmed
Eleven patients with NCAH due to 11 - beta OH deficiency and 15 control subjects were involved in the study . - pubmed
The main complaint of the patients with NCAH was hirsutism and the diagnosis was made if the adrenal 11 - deoxycortisol response to SDT exceed threefold the 95th percentile of controls . - pubmed
Peak 11 - deoxycortisol responses to LDT were significantly ( p & lt ; 0.05 ) higher in NCAH patients ( 15.7 + /- 1.8 nmol / L ) than in the control subjects ( 6.5 + /- 0.8 nmol / L ) . - pubmed
Incidence of juvenile osteodystrophy in hand - reared grey parrots ( Psittacus e erithacus ) . - pubmed
Amiodarone induced corneal deposits are the most common reversible side effects ( 70 - 100 % ) in humans . - pubmed
During follow - up for 1 - 122 months ( mean 27,3+/-1,5 months ) signs of keratopathy were found in 280 patients ( 93,9 % ) . - pubmed
The fact that coliform - free rabbits tolerate exposure to a degree and duration of hemorrhagic shock which is lethal for rabbits that possess the normal flora , and that these tolerant rabbits lose their tolerance when E. - pubmed
That there is a proportionality between the size of the pool of endotoxin and the tolerance of hemorrhagic shock is suggested by the survival rate of several series of coliform - free rabbits fed E. - pubmed
BACKGROUND : Epidemiological studies have linked the consumption of chlorinated surface waters to an increased risk of two major causes of human mortality , colorectal and bladder cancer . - pubmed
CDC Earl ' , predominated over H97 - 2 , isolated from the susceptible cv . ' Harrington ' , from the first to the last of four infection cycles on both ' CDC Earl ' and ' Harrington ' . - pubmed
PATIENTS AND METHODS : All 8 patients suffered from progressive loss of vision caused by exudation into the macular area . - pubmed
RESULTS : All patients showed complete regression of the tumor . - pubmed
No patient showed any sign of recurrence during the follow - up of up to 60 months . - pubmed
CONCLUSION : The long - term results of patients with active choroidal hemangioma demonstrate that PDT is a most effective and safe treatment option . - pubmed
We are reporting a case of an immunocompromised patient with invasive aspergillosis ( IA ) who developed aspergillotic granulomas and a mycotic aneurysm of the superior cerebellar artery . - pubmed
At the same time , chronic UVR induced the marked epidermal hyperplasia in human and mouse skin . - pubmed
The in vivo antitumor activity of 3G3 was tested in human glioblastoma ( U118 ) and leiomyosarcoma ( SKLMS-1 ) xenograft tumor models in athymic nude mice . - pubmed
It is concluded that investigations on experimental toxicity , dietary intake , and potential human health effects of PCDEs are clearly necessary . - pubmed
PCI in ST - elevation infarction -- one flew over the cuckoo 's nest . - pubmed
We describe a case of left ventricular neurofibroma in a 56 - year - old woman with Von Recklinghausen disease . - pubmed
Endoscopic surgery for spontaneous basal ganglia hemorrhage : comparing endoscopic surgery , stereotactic aspiration , and craniotomy in noncomatose patients . - pubmed
METHODS : Ninety noncomatose patients with basal ganglia hemorrhages were randomized into 3 groups . - pubmed
Postoperatively , patients were evaluated by magnetic resonance imaging ( MRI ) , with contrast , for volume and rostral - caudal extent of scar tissue and nerve root involvement . - pubmed
Back and leg pain and quality of life were assessed by neurologic examinations and standardized patient surveys . - pubmed
Neurologic examinations and patient surveys showed substantial reductions in pain over time in both groups but no significant differences between groups . - pubmed
Concomitant use of atomoxetine and OROS - methylphenidate in a 10 - year - old child suffering from attention - deficit / hyperactivity disorder with comorbid bipolar disorder and Tourette syndrome . - pubmed
Atomoxetine and OROS methylphenidate were successfully used concomitantly in a 10 - year - old boy suffering from attention - deficit / hyperactivity disorder ( ADHD ) with comorbid bipolar disorder and Tourette syndrome ( TS ) . - pubmed
EXEGESIS : We report the case of a 69 - year - old woman treated by corticotherapy for an aortitis thought to be inflammatory , who required emergency surgery when a dissected aneurysm appeared . - pubmed
BACKGROUND : Oxidative stress is prevalent in dialysis patients and has been implicated in the pathogenesis of cardiovascular disease and anaemia . - pubmed
An 84 - year - old patient with an atrial septal defect rescued using the Amplatzer septal occluder device . - pubmed
We report the case of a rescued 84 - year - old patient with atrial septal defect ( ASD ) who was emergently admitted to our intensive care unit with progressive dyspnea requiring mechanical ventilation for severe anoxia and respiratory arrest . - pubmed
Obesity is considered a mild inflammatory condition and predisposes individuals to an increased risk of developing many diseases . - pubmed
The results reported by Croci and Zarini in this issue highlight the anti - inflammatory and anti - hyperalgesic effect of rimonabant in obese animals , so suggesting that it could provide a more general and aggressive strategy to protect obese patients from many pathological risks . - pubmed
BACKGROUND : Malignant gliomas are the most common primary brain tumours of both children and adults . - pubmed
Significant attention has been given , recently , to immunotherapy which , although promising in preclinical studies , has not yet enhanced the survival of patients with glioblastomas . - pubmed
In the study we present treatment , dealing with operative difficulties and rehabilitation in a 52 - year - old patient with an inveterate fracture of the Barton type of the distal radius with dislocation in the radiocarpal joint . - pubmed
Asthma is a common condition that can substantially affect patients ' quality of life . - pubmed
However , we report a case of paradoxical bronchoconstriction in a 36 - year - old man who was recently diagnosed as having new - onset asthma and was treated with levalbuterol . - pubmed
These findings support the study of the use of the combination of bortezomib and CGC-11093 in MM patients that fail to respond to frontline therapy . - pubmed
Prosthesis type has minimal impact on survival after valve surgery in patients with moderate to end - stage renal failure . - pubmed
BACKGROUND : Few previous studies have reported on the outcome of patients with renal failure ( RF ) undergoing valvular surgery , particularly with regard to choice of valve prosthesis . - pubmed
METHODS : We retrospectively analyzed prospectively collected data from 155 patients with RF ( mean age 62 + /- 14 , 42 % female ) who underwent left - sided valve surgery from January 1998 to December 2006 . - pubmed
Patients were divided into two groups : Group 1 ( non - dialysis - dependent renal failure ( NDRF ) ; creatinine & gt;2.5 mg / dl ; n = 47 , 40 % ) and Group 2 ( renal failure dialysis ( DRF ) ; n = 108 , 60 % ) . - pubmed
Moreover , OXM ameliorates hyperglycemia and significantly reduces apoptosis in murine beta - cells after streptozotocin administration and directly reduces apoptosis in thapsigargin - treated INS-1 cells . - pubmed
Results indicate that acute MDMA , at dose of 3 mg / kg , notably impaired copulatory behavior of sexually experienced male rats . - pubmed
Fusarium culmorum causes ear blight disease on cereal crops resulting in considerable losses to grain yield , quality and safety . - pubmed
In this study , the Arabidopsis floral infection model was used to assess the impact of five defence mutants on disease . - pubmed
PATIENT(S ): Women were divided into two groups : leiomyoma ( n = 120 ) and nonleiomyoma ( n = 112 ) . - pubmed
DESIGN : Patients ( n = 203 ) with a diagnosis of gastroesophageal cancer underwent nutritional assessment ( body mass index , anthropometric measures , dysphagia scoring , and estimation of dietary intake ) . - pubmed
Excretory - secretory products of Toxocara canis larvae have been considered as a major functional antigen in immune responses against toxocariasis . - pubmed
Children born small for gestational age or with very low birth weight : clinical similarities and potential benefits of growth hormone therapy . - pubmed
In particular , two research areas need special focus in short VLBW children : the effects of growth hormone treatment ( which shows dose - dependent efficacy on postnatal growth in short SGA children ) , and insulin sensitivity ( which seems altered , as in short SGA children ) . - pubmed
The importance of valve sparing tumour resection even in asymptomatic patients is emphasised . - pubmed
We examined oxidative stress markers of 31 patients suffering from ALS , 24 patients suffering from PD and 30 healthy subjects were included . - pubmed
A trend for an enhancement of oxidized glutathione was noted in ALS patients . - pubmed
BACKGROUND : Neuroimaging and electrophysiologic studies have consistently provided evidence of impairment in anterior cingulate cortex / medial frontal cortex function in people with schizophrenia . - pubmed
RESULTS : In schizophrenia subjects , we found decreased blood oxygen level - dependent signal in the medial frontal wall , with significant clusters restricted to more dorsal regions compared with healthy subjects . - pubmed
In addition , we observed a trend - level decrease in N - acetylaspartate / creatine ( NAA / Cr ) levels and a significant positive correlation between NAA / Cr level and the blood oxygen level - dependent signal in schizophrenia subjects that did not exist in healthy subjects . - pubmed
[ Reduced cardiopulmonary exercise capacity in patients with chronic heart failure : impact of left ventricular systolic dysfunction ] . - pubmed
OBJECTIVE : To evaluate the cardiopulmonary exercise capacity in patients with chronic heart failure ( CHF ) . - pubmed
There were 37 patients with LVEF & lt ; 0.45 in CHF group and another 37 patients with LVEF & gt ; 0.50 in control group . - pubmed
CONCLUSION : ( 1 ) Cardiopulmonary exercise capacity is reduced in CHF patients . - pubmed
Benefits of dental implants installed during ablative tumour surgery in oral cancer patients : a prospective 5 - year clinical trial . - pubmed
OBJECTIVE : This prospective study assessed treatment outcome and patient satisfaction of oral cancer patients with a mandibular overdenture on implants up to 5 years after treatment . - pubmed
MATERIALS AND METHODS : At baseline , 50 consecutive edentulous oral cancer patients , in whom prosthetic problems were expected after oncological treatment , were evaluated by standardized questionnaires and clinical assessments . - pubmed
RESULTS : At the 5 - year evaluation , 26 patients had passed away and four patients had to be excluded from the analyses , because superstructures were not present , due to persistent local irritation ( n=2 ) , loss of three implants ( n=1 ) and the impossibility of making an overdenture related to tumour and oncological surgery - driven anatomical limitations ( n=1 ) . - pubmed
CONCLUSIONS : It was concluded that oral cancer patients can benefit from implants installed during ablative surgery , with a high survival rate of the implants , a high percentage of rehabilitated patients and a high denture satisfaction up to 5 years after treatment . - pubmed
BACKGROUND : Patients with single left ventricle ( LV ) physiology maybe at increased risk for myocardial dysfunction and mechanical dyssynchrony . - pubmed
Modified Yu index for strain and strain rate time to peak was longer in the single LV patients vs. controls ( 51.2 + 18.2 ms vs. 27.9 + 8.0 ms and 90.2 + 24.2 ms vs. 52.5 + 23.7 ms , respectively ) . - pubmed
Moreover , plasma levels of adipokines have been investigated in patients with nonalcoholic fatty liver disease in order to establish correlations with the underlying state of insulin resistance and with the type and severity of hepatic damage . - pubmed
In humans , decreased PPI has been reported to be associated with anxiety . - pubmed
Percutaneous versus surgical revascularization in patients with ischemic mitral regurgitation . - pubmed
BACKGROUND : The proper way of revascularization remains controversial in patients with ischemic mitral regurgitation ( IMR ) . - pubmed
BACKGROUND : Aerosol delivery of surfactant and perfluorocarbon ( PFC ) is a desirable therapeutic approach for the treatment of various lung diseases in patients undergoing mechanical ventilation . - pubmed
Renal disease affects approximately 30 % of patients with JBTS , presenting itself in most cases as nephronophthisis ( NPHP ) , a structural tubulo - interstitial disorder characterized by thickened basal membrane of the tubular epithelium and progressive interstitial fibrosis , associated with cysts at the cortico - medullary junction . - pubmed
We propose three cases concerning three patients with JBTS having different years of illness and degrees of renal impairment , evaluating the parameters of renal function at the time of genetic diagnosis and seen after a follow - up of 7 years . - pubmed
The aim of this study was to investigate the difference between the pharmacokinetics of haloperidol in normal rats and in rats with fatty liver disease . - pubmed
A therapeutic dosage ( 0.1 mg / kg ) and a toxic dose ( 15 mg / kg ) of haloperidol were administrated to normal 9 - week - old male rats or those with severe fatty liver disease , and the blood concentration of haloperidol was determined 15 min , 1 , 2 , and 3 h following haloperidol administration . - pubmed
When given at the therapeutic dosage , the concentrations of haloperidol in both the blood and organs of the rats with fatty liver disease were significantly higher than those in the normal rats . - pubmed
However , when given at the toxic level , the blood and organ haloperidol concentrations 1 h after administration tended to be lower in the rats with fatty liver disease than those in the normal rats ; these lower haloperidol levels returned to be the levels in the normal rats 3 h after the administration of haloperidol . - pubmed
However , the volume did not change after the toxic or the therapeutic dose of haloperidol compared with pre - administration in rats with severe fatty liver disease , although it was significantly higher than in the normal rats . - pubmed
The pathway for haloperidol metabolism might have been saturated before the administration of haloperidol in rats with fatty liver disease ; thus , it is possible that the blood concentration of haloperidol tends to be much higher in individuals with severe fatty liver disease than in those with normal livers in an inverse proportion to the dosage of haloperidol . - pubmed
Phase 2 study of rituximab plus ABVD in patients with newly diagnosed classical Hodgkin lymphoma . - pubmed
In the present study , we evaluated the efficacy and safety of rituximab in combination with standard doxorubicin , bleomycin , vinblastine , and dacarbazine ( RABVD ) in patients with classical Hodgkin lymphoma ( cHL ) . - pubmed
In this phase 2 study , patients with chemotherapy - naive , advanced - stage cHL were treated with rituximab 375 mg / m(2 ) weekly for 6 weeks and standard ABVD for 6 cycles . - pubmed
Our results demonstrate that the addition of rituximab to ABVD is safe and has a promising clinical activity in patients with advanced - stage cHL . - pubmed
19 studies focused on samples with a majority of dysthymic patients . - pubmed
Our 20 - year - old patient presented with cardiovascular collapse , raised anion gap metabolic acidosis and non - ketotic hypoglycaemia . - pubmed
All patients with persistent severe CVS should have metabolic investigations to exclude disorders of fatty acid oxidation . - pubmed
Zebrafish share many gene functions with other vertebrates including humans , making zebrafish a useful system for studying cancer etiology . - pubmed
Cognitive remediation in schizophrenia : efficacy and effectiveness in patients with early versus long - term course of illness . - pubmed
Subdural hemorrhage in pediatric patients with enlargement of the subarachnoid spaces . - pubmed
Therefore , the authors evaluated the frequency of SDH in a cohort of children with enlargement of the subarachnoid spaces . - pubmed
The authors excluded children who had enlargement of the subarachnoid spaces diagnosed on imaging performed for trauma or developmental delay , as well as children with a history of prematurity , diagnosis of intracranial pathology , or metabolic or genetic disorders . - pubmed
Chart review recovered the following data : patient demographics , head circumference , history of head trauma , and head imaging results . - pubmed
For the subset of children with SDH , information regarding evaluation for other injuries , including skeletal survey , ophthalmological examination , and child protection team evaluation , was abstracted . - pubmed
RESULTS : There were 177 children with enlargement of the subarachnoid spaces who met the inclusion criteria . - pubmed
Subdural hemorrhage was identified in 4 ( 2.3 % ) of the 177 children . - pubmed
All of the children with SDH underwent evaluations for suspected nonaccidental trauma , which included consultation by the child protection team , skeletal survey , and ophthalmological examination . - pubmed
Evidence of additional injuries concerning for physical abuse were identified in a quarter of the children with enlargement of the subarachnoid spaces and SDH , suggesting that an evaluation for suspected nonaccidental trauma including occult injury screening should be performed in cases of SDH with enlargement of the subarachnoid spaces . - pubmed
They were classified as MCI or AD patients . - pubmed
Predictors of good functional outcome in counterpulsation - treated recent ischaemic stroke patients . - pubmed
Among all 207 recruited cases , 119 ( 57.5 % ) patients had a good outcome at 3 months after stroke . - pubmed
In humans , their dysfunction has been linked to diseases , such as hypertension , heart failure and epilepsy , and they are well - established drug targets . - pubmed
Vaccines are predicted to play an important role in H5N1 control should the virus become readily transmissible between humans . - pubmed
Children with neurodevelopmental disorders are at increased risk for sleep issues , which affect quality of life , cognitive function , and behavior . - pubmed
To determine the prevalence of sleep problems in children with the common neurodevelopmental disorder neurofibromatosis type 1 , a cross - sectional study was performed on 129 affected subjects and 89 unaffected siblings , age 2 to 17 years , using the Sleep Disturbance Scale for Children questionnaire . - pubmed
Children with neurofibromatosis type 1 were significantly more likely to have disturbances in initiating and maintaining sleep , arousal , sleep - wake transition , and hyperhidrosis , but not problems with abnormal sleep breathing , or excessive somnolence . - pubmed
We tested for this association in a case - control study in 100 Iranian sporadic LOAD patients based on diagnostic criteria of DSM - IV - TR and NINCDS - ADRDA and in 100 normal controls without any personal and family history of AD or other related dementias . - pubmed
Our study demonstrated that T - carrying genotype frequency in AD patients is significantly higher than in controls and there was a 2.5 - fold increased risk for developing AD in the T - carrying genotype compared to C / C genotype ( odds ratio = 2.5 , p = 0.010 ) . - pubmed
Lung cancer is the primary cause of cancer - related mortality worldwide and although improvements in treatment have been achieved over the last few years , long - term survival rates for lung cancer patients remain poor . - pubmed
This article describes a 55 - year - old man with a well - delimited , oval - shaped , radiolucent lesion , occupying the middle and apical third of teeth 22 and 23 . - pubmed
MATERIALS AND METHODS : Fifty - six boys with severe haemophilia A and B and 56 healthy peers between the ages of 7 - 12 in need of primary dental extraction were chosen for this study . - pubmed
Effect of cefepime dose on mortality of patients with Gram - negative bacterial bloodstream infections : a prospective cohort study . - pubmed
We evaluated the effect of cefepime on the mortality of patients with GNB bloodstream infections ( BSIs ) . - pubmed
METHODS : A prospective cohort study was conducted in adult patients with creatinine & lt;=1.5 mg / dL who received empirical therapy with cefepime for at least 48 h for BSIs caused by GNB . - pubmed
CONCLUSIONS : High - dose cefepime therapy was associated with lower mortality rates in patients with GNB BSIs , even for GNB with low cefepime MICs . - pubmed
METHODS : Four patients with Hailey - Hailey disease were examined by RCM . - pubmed
Characterisation of pyrazinamide - resistant Mycobacterium tuberculosis strains isolated in Poland and Germany . - pubmed
Although the majority of the cancer studies have focused on the functions of protein - coding genes , emerging evidence has started to reveal the importance of the vast non - coding genome , which constitutes more than 98 % of the human genome . - pubmed
A number of non - coding RNAs ( ncRNAs ) derived from the ' dark matter ' of the human genome exhibit cancer - specific differential expression and/or genomic alterations , and it is increasingly clear that ncRNAs , including small ncRNAs and long ncRNAs ( lncRNAs ) , play an important role in cancer development by regulating protein - coding gene expression through diverse mechanisms . - pubmed
RESULTS : Growth retardation of mouse zygotes was greater in 20 % O2 than 5 % , a sequential media design was superior to static simple media designs , but the supplementation of simple media with mixed amino acids mitigated this difference . - pubmed
OBJECTIVE : Hepatitis C virus ( HCV ) has emerged as a leading cause of chronic hepatitis , liver cirrhosis and hepatocellular carcinoma worldwide . - pubmed
The purpose of this study was to describe the distribution pattern of HCV genotypes in chronic hepatitis patients in the Campania region of southern Italy and estimate their association with risk factors and viral load . - pubmed
CONCLUSION : The present study revealed that HCV genotypes 1 and 2 accounted for over 95 % of all HCV infections in the Campania region , and genotype 1 was more frequently associated with a higher viral load when compared to genotypes 2 and 3 . - pubmed
Rarely , patients may present with two distinct pituitary tumors . - pubmed
To date , the patient has been followed - up for 3 years without medical intervention and without visual deterioration . - pubmed
Thrombocytopenia affects patients undergoing liver transplantation . - pubmed
Graft and overall survival in patients with different degrees of thrombocytopenia and with or without intraoperative platelet transfusion were described . - pubmed
However , the utility of this technique for parapharyngeal abscesses in paediatric patients has not been investigated . - pubmed
This paper describes an intraoral drainage technique combined with tonsillectomy for treating children with a parapharyngeal abscess that obviates the need for skin incision . - pubmed
In addition , both patients suffer from a polyneuropathy . - pubmed
Safety of ferric carboxymaltose immediately after infliximab administration , in a single session , in inflammatory bowel disease patients with iron deficiency : a pilot study . - pubmed
IBD patients were recruited consecutively in the outpatient clinic in two groups . - pubmed
All patients received 5mg / kg IFX and 1000 mg FCM for iron - restricted anemia ( IRA ) or 500 mg FCM for iron deficiency without anemia . - pubmed
RESULTS : All 45 patients ( 35 Crohn s disease , 10 ulcerative colitis ) received IFX 5mg / kg . - pubmed
CONCLUSION : Single - session administration of FCM after IFX was safe and effective in IBD patients and can offer a good cost - benefit ratio and improve treatment adherence . - pubmed
The genetic basis of SSB is almost wholly unknown in non - human animals , though this is key to understanding its persistence . - pubmed
CONCLUSIONS : Compared with conventional ( steroid or placebo injection ) therapy , BTX injections have beneficial effects for adult patients with shoulder pain , evidenced by improved pain scores and ROM . - pubmed
Autism characteristics in sixty children ( aged from 2 to 8) were assed . - pubmed
The liver fluke Opisthorchis felineus is a member of the triad of epidemiologically important liver fluke species belonging to the family Opisthorchiidae and the major agent causing opisthorchiasis over a vast territory , covering Russia , Kazakhstan and several European countries . - pubmed
The International Agency for Research on Cancer classified O. - pubmed
Here , we investigated the link between altered breast cancer metabolism and AI resistance using AI - resistant and sensitive breast cancer cells , patient tumor samples , and AI - sensitive human xenografts . - pubmed
There was no significant difference in prevalence of infection or heavy - intensity infection of either schistosome species between attending and non - attending children , apart from heavy - intensity S. - pubmed
METHODS : A retrospective analysis was conducted of 163 locally advanced unresectable consecutive pancreatic adenocarcinoma patients who received chemoradiotherapy in Zhejiang cancer hospital from January 2009 to December 2011 . - pubmed
Patients with higher MDW had a 1.48 - fold increased risk of death compared to those with low MDW . - pubmed
CONCLUSIONS : MDW is an independent negative prognostic factor for overall survival in pancreatic adenocarcinoma patients . - pubmed
Optimal revascularization strategy in patients with multi - vessel coronary artery disease remains a matter of debate , with advantages and disadvantages in both surgical and percutaneous procedures . - pubmed
[ Sepsis associated encephalopathy is an independently risk factor for nosocomial coma in patients with supratentorial intracerebral hemorrhage : a retrospective cohort study of 261 patients ] . - pubmed
OBJECTIVE : To investigate whether the presence of sepsis associated encephalopathy ( SAE ) would predict nosocomial coma ( NC ) and poor outcome in patients with supratentorial intracerebral hemorrhage ( SICH ) . - pubmed
The adult acute SICH patients with or without coma admitted to intensive care unit ( ICU ) of Shuyang People ' Hospital Affiliated to Xuzhou Medical University from December 2012 to December 2015 were enrolled . - pubmed
Univariate and Cox regression analyses were performed to analyze whether SAE would predict NC and poor outcome in patients with SICH . - pubmed
RESULTS : A total of 330 patients with acute SICH and coma were enrolled , excluding 60 cases of infratentorial cerebral hemorrhage , 3 cases of primary intraventricular hemorrhage , and 6 cases of unknown volume hematoma . - pubmed
It was shown by Cox regression analyses that SAE [ hazard ratio ( HR ) = 3.5 , 95 % confidence interval ( 95%CI ) = 1.346 - 6.765 , P = 0.000 ] and SOFA score ( HR = 1.8 , 95%CI = 1.073 - 1.756 , P = 0.008 ) were independent risk factors of death of SICH patients with NC , and hematoma enlargement was independent risk factor of death of SICH patients with PC ( HR = 3.0 , 95%CI = 1.313 - 5.814 , P = 0.000 ) . - pubmed
One patient experienced an intra - abdominal abscess potentially related to delayed perforation as a postoperative complication . - pubmed
HAEC was the first clinical manifestation in 25 ( 61 % ) of the patients with HD . - pubmed
Time is the enemy : Mortality in trauma patients with hemorrhage from torso injury occurs long before the " golden hour " . - pubmed
CONCLUSION : In patients with high - grade torso injury , AIS grades & gt;=4 , the degree anatomic disruption is associated with significant hemorrhage . - pubmed
In our study , a precipitous rise in patient mortality was exhibited in this high - grade injury group at prehospital times & lt;30 min . - pubmed
Our data highlight the critical nature of prehospital time in patients with non - compressible torso hemorrhage . - pubmed
METHODS : Fifty - four patients with primary Sjogren syndrome , 35 patients without primary Sjogren syndrome ( patients with dry mouth and dry eye symptoms ) , and 52 healthy control volunteers were included in this study . - pubmed
Patients with primary Sjogren syndrome were classified as early or advanced stage by labial gland biopsies . - pubmed
Hypogonadotropic Hypogonadism in Males with Glycogen Storage Disease Type 1 . - pubmed
Case Studies and Methods : Four unrelated patients with GSD 1a ( N = 1 ) and 1b ( N = 3 ) were found to have hypogonadotropic hypogonadism diagnosed at different ages . - pubmed
In addition , all patients were found to have disproportionately low bone mineral density at the lumbar spine compared to the hip . - pubmed
Common to all patients was erratic metabolic control , including recurrent hypoglycemia and elevated lactate levels . - pubmed
Patients with and without NLS were compared using the chi2 - test or Mann - Whitney U - test . - pubmed
Patients with NLS showed significantly higher maximum pain scores at every measurement time point : average difference ( = 3 , adjusted p & lt ; 0.005 ) , a higher impairment due to pain ( = 15 , adjusted p & lt ; 0.005 ) , more anxiety ( = 3 , adjusted p & lt ; 0.005 ) , depression ( = 3 , average adjusted p & lt ; 0.003 ) and kinesiophobia ( = 4 , preoperative not significant , average postoperative adjusted p = 0.004 ) . - pubmed
In patients with CPSP , NLS occurred significantly more often ( 74 % ) than in patients without clinically relevant pain ( 17.5 % . - pubmed
CONCLUSION : The occurrence of NLS is associated with higher pain scores , more impairment due to pain and a higher psychosocial burden and they are more frequent in patients with CPSP . - pubmed
PATIENT CONCERNS , DIAGNOSES , INTERVENTIONS , AND OUTCOMES : Here we report an FD patient with widespread gastrointestinal angiokeratomas who developed life - threatening bleeding following anticoagulation for atrial fibrillation . - pubmed
LESSONS : Careful observation for gastrointestinal bleeding is warranted for patients on anticoagulation with extensive cutaneous angiokeratomas . - pubmed
Furthermore , our experience suggests that surveillance is needed to assess the prevalence and extent of gastrointestinal angiokeratomas in patients with FD . - pubmed
Here , we used rabbit articular chondrocytes as a cellular model to investigate the effects and regulatory mechanisms of OA on dedifferentiation and pro - inflammation . - pubmed
Diffusion tensor imaging findings suggestive of white matter alterations in a canine model of mucopolysaccharidosis type I. - pubmed
Methods Four unaffected canines and two canines with MPS were euthanized at 18 weeks of age . - pubmed
These findings suggest that the canine model parallels MPS in humans , and further indicates that quantitative DTI analysis of such animals may be suitable for future study of disease progression and therapeutic response in MPS . - pubmed
METHODS : We retrospectively reviewed 34 patients with symptomatic lumbar ganglion cysts treated with spinal canal decompression with or without spinal fixation . - pubmed
Then , ethanol fermentation using the ethanologenic bacterial strain Z. - pubmed
INTRODUCTION : Extracorporeal membrane oxygenation ( ECMO ) provides mechanical pulmonary and circulatory support for patients with shock refractory to conventional medical therapy . - pubmed
Blood - Brain Barrier and Intrathecal Immune Response in patients with neuroinfections . - pubmed
The aim of the study was to detect BBB permeability impairment and the intrathecal immune response in patients with CNS infections with various etiologies . - pubmed
The purpose of this study was to analyze the correlation between TS and risk / type of recurrence in EC patients , stratified according to the new European Society of Medical Oncology - European Society of Gynecological Oncology - European Society for Radiotherapy and Oncology classification . - pubmed
METHODS : Data of patients with histologically proven EC who received primary surgical treatment between November 1999 and June 2015 were retrospectively retrieved from 5 institutions . - pubmed
A total of 134 ( 11.5 % ) women had recurrence : 47 ( 4 % ) of them had local relapse , 30 ( 2.6 % ) had locoregional relapse , and 57 ( 4.9 % ) had distant relapse . - pubmed
Tumor size 25 mm or greater emerged as the threshold for the prediction of a higher rate of local recurrence ( P & lt ; 0.0001 , hazard ratio = 18.2 , P = 0.005 ) and a lower local recurrence - free survival and recurrence - free survival ( P & lt ; 0.0001 ) only in patients with low - risk EC . - pubmed
CONCLUSIONS : In this very large series , tumor size emerges as an independent prognostic factor of local recurrence in women with low - risk EC and could be a valuable additional criterion to personalize the treatment approach to these patients . - pubmed
METHODS : Retrievable markers were deployed into n = 28 FPAs of lightly embalmed human cadavers . - pubmed
OBJECTIVES : It is well - documented that geriatric patients are at risk for serious injuries after fracture due to pre - existing medical conditions , physical changes of aging , and medication effects . - pubmed
CONCLUSION : Frailty and surgical intervention are correlated with a higher 30 - day complication rate in patients with thoracic and thoracolumbar fracture . - pubmed
Systematic literature review on patterns of pharmacological treatment and adherence among patients with bipolar disorder type I in the USA . - pubmed
Currently , more than half of newly diagnosed cancer patients receive radiation treatment . - pubmed
RESULTS : In total , 7821 patients who underwent proximal aortic replacement from 47 studies were included : 8.3 % ( n = 649 ) had Marfan syndrome ( MS ) . - pubmed
Patients with apparently similar tumours have variable outcomes . - pubmed
Compression of the anterior visual pathways results in progressive thinning of the retinal nerve fiber layer ( RNFL ) and macular ganglion cell complex ( GCC ) and this review will highlight the utility of OCT in evaluating patients with this condition . - pubmed
RECENT FINDINGS : The RNFL and macular GCC have been found to highly correlate with visual function in patients with compressive optic neuropathies . - pubmed
Patients with an otherwise normal neuroophthalmic examination , including automated perimetry , may have macular GCC or RNFL thinning as the only manifestation of compression , enabling compressive optic neuropathies to be diagnosed at an earlier stage and managed accordingly . - pubmed
SUMMARY : Recent findings indicate that OCT is an important tool in the evaluation of patients with compressive optic neuropathies , particularly for prognosis in patients with visual field defects and diagnosis in patients with preserved or mildly reduced visual function . - pubmed
In this report , we describe a case of blunt perineal trauma and partial urethral disruption in a pediatric patient presenting with refractory anemia due to a penile artery pseudoaneurysm . - pubmed
Sclerosing angiomatoid nodular transformation of the spleen ( SANT ) in a patient with clear cell carcinoma of the uterus : a case report . - pubmed
CASE PRESENTATION : A 49 - year - old Arabic woman presented to our institute with abdominal pain and distention . - pubmed
The patient underwent surgical treatment , and the histopathological examination of the resected uterine and splenic specimens disclosed invasive uterine clear cell carcinoma and sclerosing angiomatoid nodular transformation of the spleen , respectively . - pubmed
We report the case of a HIV - positive patient with type 2 diabetes mellitus who presented with uncontrolled blood sugars after the initiation of prophylactic isoniazid ( INH ) therapy . - pubmed
The survival rate of cancer patients remains unsatisfactory due to the late diagnosis , frequent metastasis and poor response to chemotherapeutics . - pubmed
In cancer patients , it is often misdiagnosed as metastasis . - pubmed
CASE PRESENTATION : Here , we presented a case of a 50 - year - old female patient suffering from slightly headache who received breast cancer modified radical mastectomy in 2004 , computed tomography and magnetic resonance imaging findings revealed abnormal lesions of diffuse skull which were misdiagnosed as skull metastasis , and the relevant literatures were also reviewed . - pubmed
In January 2018 , NIAID convened a workshop , entitled " 3 - D Human in vitro TB Granuloma Model " to advance the field . - pubmed
Functional Improvement of Upper and Lower Extremity After Decompression and Neurolysis and Nerve Transfer in a Pediatric Patient with Acute Flaccid Myelitis . - pubmed
BACKGROUND Acute flaccid myelitis is an emerging polio - like illness mostly affecting young children , characterized by rapid onset of extremity weakness and paralysis in 1 or more limbs . - pubmed
Certain viruses , including enteroviruses such as EV-68 , EV-71 , poliovirus , and West Nile virus , can cause this disorder . - pubmed
CONCLUSIONS We demonstrated that decompression , neurolysis , and nerve transfer surgical procedures can be used successfully to correct the paralyzed upper and lower extremity movements in acute flaccid myelitis patients . - pubmed
We considered three groups of subjects : patients with a brain AVM before treatment using gamma knife radiosurgery ( GKR ) ; patients three or more years post - GKR treatment ; and healthy volunteers . - pubmed
Treatment of orthodontic patients with idiopathic condylar resorption ( ICR ) is challenging for clinicians due to the continuous change of occlusion caused by the unstable condylar position and symptoms in the temporomandibular joint ( TMJ ) . - pubmed
In this case report , a patient with Class II open bite and progressive condylar resorption was treated with an appropriate treatment protocol . - pubmed
The approved dose of oral anticoagulant rivaroxaban for patients with non - valvular atrial fibrillation ( NVAF ) in Japan is 15 mg once daily ( od ) in patients whose creatinine clearance is & gt;= 50 mL / min , but recent real - world studies have demonstrated that these patients often received less than the recommended dose due to bleeding concerns . - pubmed
After adjusting for patient characteristics by propensity scoring and inverse probability of treatment weighting , incidence rates of major bleeding were comparable between under - dosed patients and patients who received the recommended dose ( 1.34 vs. 1.63 events/100 patient - years , p = 0.197 ) , although the incidence rates of stroke / non - CNS SE / MI were higher in under - dosed patients than in those who received the recommended dose ( 2.15 vs. 1.48 events/100 patient - years , p = 0.009 ) . - pubmed
Predicting postoperative fatigue in surgically treated lung cancer patients in Norway : a longitudinal 5 - month follow - up study . - pubmed
OBJECTIVES : Despite the negative influence of fatigue on quality of life in patients who undergo lung cancer surgery , little is known about the possible predictors of postoperative fatigue . - pubmed
PARTICIPANTS : In total , 196 surgically treated patients who answered the questionnaires both preoperatively and at 5 - month follow - up with valid fatigue scores . - pubmed
RESULTS : 45 studies were identified , including 2076 knee arthroplasty patients , 620 patients with end - stage osteoarthritis and 449 healthy controls . - pubmed
The U.S. Acute Liver Failure Study Group comprised of 33 tertiary care liver centers has enrolled consecutive patients with ALF or acute liver injury ( ALI : INR>= 2.0 with no encephalopathy ) , over two decades . - pubmed
Short - term testicular warming under anesthesia causes similar increases in testicular blood flow in Bos taurus versus Bos indicus bulls , but no apparent hypoxia . - pubmed
Despite a long - standing dogma that testicular hyperthermia causes hypoxia , we reported that increasing testicular temperature in bulls and rams enhanced testicular blood flow and O2 delivery / uptake , without hypoxia . - pubmed
Our objective was to determine effects of short - term testicular hyperthermia on testicular blood flow , O2 delivery and uptake and evidence of testicular hypoxia in pubertal Angus ( B. - pubmed
Methods : We analyse demographic and clinical data from a cross - sectional survey of 400 HIV - infected patients aged > = 18 years , who were treatment - naive or switched TDF regimen within over 3 years between November 2018 and March 2019 . - pubmed
Computed tomography angiography of 155 patients who underwent TAVR using a SAPIEN 3 were used to identify patients with and without thrombosis , and quantify thrombus volumes . - pubmed
The aim of this review is to provide an overview of the c - miRNAs suggested as promising biomarkers for osteoporosis up until now , which could be helpful for early diagnosis and monitoring of treatment response , as well as fracture risk assessment , in osteoporotic patients . - pubmed
Likewise , an increase in the lipid peroxidation and protein carbonyls was also observed throughout the plant regardless the inoculated strain , while chlorophylls and carotenes were increased only in those inoculated with Bradyrhizobium sp . - pubmed
All these findings allowed us to conclude that the redox response of peanut is conditioned by the rhizobial strain , which contributes to the importance of effectively formulating bioinoculants for this crop . - pubmed
Potentially inappropriate anticholinergic drug prescriptions for patients with Sjogren ' s syndrome . - pubmed
A total of 4945 patients with Sjogren ' s syndrome were identified , with a mean age of 64.6 + - 14.04 years and 75.7 % women . - pubmed
Most patients with Sjogren ' s syndrome were women whose symptomatic management mainly included ocular lubricants with low use of oral pilocarpine . - pubmed
Similar hypoglycemic effects of glucomannan and its enzyme degraded products from Amorphophallus albus on type 2 diabetes mellitus in mice and potential mechanisms . - pubmed
In the present study , the hypoglycemic effects of glucomannan ( AGM ) and its enzyme - degraded products from Amorphophallus albus were investigated . - pubmed
It was speculated that the hypoglycemic activity of AGM is decided by not the molecular weight but the glycosidic bonds / monosaccharide composition of AGM , which might be structurally specific to the gut bacteria , and thus certain SCFAs and endogenous metabolites that are related to the occurrence and therapy of T2DM . - pubmed
While this is a rare occurrence we report , the incidental finding of pacemaker lead malposition during a routine follow - up transthoracic echocardiogram and the benefits of three - dimensional transesophageal echocardiography in this patient prior to lead extraction . - pubmed
Additive manufacturing is a key technology required to realize the production of a personalized bone substitute that exactly meets a patient 's need and fills a patient - specific bone defect . - pubmed
Cytomegalovirus ( CMV)-associated portal vein thrombosis in a healthy , immunocompetent man . - pubmed
We present a previously healthy man in his 30s who presented with typical viral prodrome symptoms and worsening abdominal pain . - pubmed
Three cases of ischaemic cardio - vascular accidents are reported under progestative treatment ; the drug used was chlormadinone acetate ( 0,5 mg daily ) in one patients , and norethisterone ( 5 mg daily ) in two others . - pubmed
Immunity to malaria in many species , including man , is acquired only after long exposure to infection and is associated with chronic low - grade parasitaemia . - pubmed
Effect of cimetidine on chronic gastric ulcers produced experimentally in rats . - pubmed
The authors have studied the effects of cimetidine on the healing of chronic gastric ulcers induced in rats . - pubmed
The cell line on inoculation(ip ) in neonatal BALB / c mice produced lymphomic lesions in almost all the vital organs of the mice . - pubmed
Amyloidosis , hemochromatosis , and atherosclerosis in a roseate flamingo ( Phoenicopterus ruber ) . - pubmed
Clinical findings and cranial CT scan identified stroke in 315 admitted patients at Taichung Veterans General Hospital from January 1 , 1989 to December 31 , 1989 . - pubmed
The mean age of patient with cerebral infarction was 64.8 years , which was about 3.3 years higher than those with cerebral hemorrhage ( mean age 61.5 years ) . - pubmed
Tumor staging tended to be significantly more advanced in OG patients ( chi - square = 9.054 ; df = 3 ; P = 0.026 ) . - pubmed
Hypertrophy of smooth muscle occurs in various medical conditions and several methods are available for inducing it experimentally in laboratory animals , especially in urinary bladder , small intestine and ureter . - pubmed
The hypertrophic response differs somewhat with the type of organ , the animal species , the age of the subject , and the experimental procedure . - pubmed
Because the response of lymphocytes from different lymphocyte compartments may vary , we compared the responses of murine peripheral blood , splenic , Peyer 's patch , and mesenteric lymph node lymphocytes to a battery of mitogens after thermal injury . - pubmed
The 80 micrograms / ml concentration is 5 times that found in the serum of subjects treated with 200 mg of etodolac twice a day for 6 days , and 33 times the concentration in synovial fluid of arthritic patients treated with etodolac 200 mg twice a day for 7 days . - pubmed
In this work we have analyzed the factors that could potentially account for the differential effect of 5 '- AdThd among various cell types : 647V ( a human bladder cancer cell line ) ; HU ; SV - HU ( a SV40 - transformed human urothelial cell line ) , and C3H / 10T1 / 2 mouse embryo fibroblasts ( 10T1 / 2 ) cells . - pubmed
WN-25 , when injected intravenously , can cause the death of mice only if the function of the BBB is impaired . - pubmed
Staphylococcus intermedius in canine gingiva and canine - inflicted human wound infections : laboratory characterization of a newly recognized zoonotic pathogen . - pubmed
aureus by the following characteristics : coagulation of rabbit plasma at 4 h ( 26 versus 100 % , respectively ) , hemolysis of sheep blood at 24 h ( 30 versus 79 % , respectively ) , and mannitol fermentation at 24 h ( 4 versus 93 % , respectively ) . - pubmed
Fourteen previously collected strains of coagulase - positive staphylococci from infected canine - inflicted human wounds were reanalyzed ; 3 of 14 ( 21 % ) isolates were S. - pubmed
intermedius is a common canine gingival flora and is responsible for some canine - inflicted human wound infections , thus representing a newly recognized zoonotic pathogen . - pubmed
We assume a compensated metabolic Se - deficiency state in mice under these nutritional conditions , which leads to expression of enhanced metabolic capacity when induced by stress . - pubmed
Four of 132 consequtive patients with paraproteinemia and with an M - component presented exclusively with neurological symptoms . - pubmed
Based on these findings the pathogenesis of neuropathy in patients with paraproteinemia is discussed , and it is concluded that although there is evidence for immune - mediated neuropathy in the patients , the histologic , immunohistochemical and clinical data are conflicting and the exact pathogenic pathway is still unknown . - pubmed
To study the natural history of scoliosis in institutionalized adults who have cerebral palsy , we reviewed retrospectively the cases of fifty - one patients . - pubmed
All patients had had penetrating injuries of the heart , ascending aorta , or aortic arch 1 week to 4 years earlier , but only three had an early emergency operation . - pubmed
Eleven patients ( 35 % ) had ventricular septal defects and seven ( 23 % ) had other types of intracardiac fistulas . - pubmed
The remaining 13 patients had fistulas between the aorta and the main pulmonary artery or innominate vein . - pubmed
Metoclopramide potentiates d - amphetamine - induced hypermotility and stereotypy in rat . - pubmed
Two patients have been treated in this manner , and more than 3 years after the operations , both patients were still improving neurologically without any evidence of tumor recurrence . - pubmed
In the present study , we produced hybridomas by fusing lymphocytes from 13 systemic lupus erythematosus patients with the GM 4672 lymphoblastoid line . - pubmed
A decreased number of marrow CFU - e and peripheral reticulocytes was observed in the mice with relative polycythemia induced by dehydration as well as in the mice with absolute polycythemia induced by hypertransfusion . - pubmed
Starting 2 weeks later , 1 to 5 micrograms ( depending on strain ) of 12 - O - tetradecanoylphorbol-13 - acetate ( TPA ) in 0.2 mL acetone / mouse was applied three times weekly to the shaved back for 20 weeks . - pubmed
This treatment resulted in 51/57 animals developing lung adenomas vs. 5/57 in the control animals . - pubmed
In control animals treated with NPYR we observed 3/26 animals with tracheal papillomas , and 6/26 animals with hepatic neoplastic nodules . - pubmed
In addition , significantly elevated percentages of TdT+ bone marrow cells ( presumptive prothymocytes ) were present in NZB , NZW , and NZB / W mice between 1 and 4 wk of age , with the highest mean peak levels occurring in the NZB strain . - pubmed
In contrast , PGF2 alpha , which is not therapeutically active against autoimmunity in NZB / W mice , had no detectable effect on TdT+ bone marrow cells or thymocytes in BALB / c or NZB / W mice . - pubmed
The results also raise the possibility that the therapeutic efficacy of exogenous PGE1 in autoimmune NZ strain mice may be related , at least in part , to its ability to rectify the abnormal development of these early lymphoid cells . - pubmed
Abnormalities at the B - cell level in patients with Behcet ' s disease ] . - pubmed
2nd communication : Use of suprofen suppositories as an antipyretic in children with fever due to acute infections / A single - blind controlled study of suprofen versus paracetamol . - pubmed
The present randomized single - blind trial was performed to study antipyretic effect and tolerability of alpha - methyl-4 -( 2 - thienylcarbonyl )- phenyl acetic acid ( suprofen , Suprol ) suppositories versus paracetamol ( acetaminophen ) suppositories in pediatric patients with fever of various etiology . - pubmed
Fluid intake behavior in patients with spinal - cord injury : prediction and modification . - pubmed
Immunofluorescent techniques were used to follow the replication of the SF-4 strain of bovine para - influenza 3 ( PI-3 ) virus in Madin - Darby Bovine Kidney ( MDBK ) , secondary bovine kidney ( BK ) , Embryonic Bovine Trachea ( EBTr ) cell cultures and experimentally infected hamsters . - pubmed
Infection was limited to the epithelial lining of the upper respiratory tract , trachea and bronchi of experimentally infected hamsters . - pubmed
[ State of the cardiovascular system in patients with osteoarthrosis deformans treated at the Khmel'nik health resort with radon - oxygen baths ] . - pubmed
[ Studies on the hypoglycemic activity of guava , sugar cane fibers and pig 's pancreas on diabetic patients ] . - pubmed
[ Blood copper content and its diurnal excretion in urine in patients with coronary atherosclerosis ] . - pubmed
[ Glutatione in the blood of patients with atherosclerosis and the effect of iodine therapy ] . - pubmed
The effectiveness of sultopride in acute psychiatric syndromes with prominent agitation was tested in patients seen in the emergency department of a general hospital . - pubmed
Structural adaptation of the vascular bed in the broad ligament of the dog uterus has been studied at various time of the experimental phlebohypertension . - pubmed
Patients experiencing hypotension in this group showed a sharp rise in NE , suggesting baroceptor - mediated adrenergic stimulation . - pubmed
In all patients sustaining hypotension during therapy , postdialysis PRA was closely correlated with NE . - pubmed
Quantitative investigation on the urinary excretion and metabolism of 3,4 - dimethoxyphenylethylamine in schizophrenics and normal individuals . - pubmed
The DMPEA content was measured in urine from healthy persons , from schizophrenics , and from psychiatric patients without schizophrenia hospitalized with the schizophrenics . - pubmed
DMPEA could be found neither in schizophrenics nor in controls or healthy persons . - pubmed
All strains reacted with C. - pubmed
The strains L. - pubmed
donovani strains from Sudan can not be distinguished from the Indian strain L. - pubmed
Effects on renal function of a low - nitrogen diet supplemented with essential amino acids and ketoanalogues and of hemodialysis and free protein supply in patients with chronic renal failure . - pubmed
The effect of N -( 2 - carboxyphenyl )- 4 - chloroanthranilic acid disodium salt ( CCA ) on spontaneous autoimmune disorders in MRL / l mice . - pubmed
Cross - reactivity between bacterial epitopes and cartilage components has been assumed to play a role in the pathology of bacterial - induced arthritis models . - pubmed
In this study , we report prominent proteoglycan ( PG ) depletion in Safranin - O stained ankle joint sections from collagen - induced arthritic rats . - pubmed
In vitro , PG fractions were able to stimulate T lymphocytes from these arthritic rats . - pubmed
These data suggest that cross - reactivity between bacterial epitopes and PG does not seem to be a key element in the onset of joint inflammation in bacterial - induced arthritis . - pubmed
We characterized structural and functional changes of these lipoproteins in six patients with cholesteryl ester transfer protein ( CETP ) deficiency . - pubmed
Relation to age , sex , weight , height , diabetes , serum lipids and consumption of coffee , tobacco and alcohol . - pubmed
Sixty - three patients with a DSM - III diagnosis of chronic schizophrenia served as subjects . - pubmed
Prediction of survival in patients with suspected recurrent cerebral tumors by quantitative thallium-201 single photon emission computed tomography . - pubmed
PURPOSE : To assess whether quantitative 201Tl single photon emission computed tomography ( SPECT ) can be used as a prognostic test in patients with suspected recurrent cerebral tumor , regardless of various combined therapies given . - pubmed
METHODS AND MATERIALS : The study population consisted of 22 patients with grade 4 , 3 , or 2 glioma and 7 patients with solitary cerebral metastasis . - pubmed
Each patient underwent 201Tl brain SPECT to differentiate recurrent tumor from cerebral radiation necrosis , because the prior computed tomography and/or magnetic resonance imaging showed a mass lesion with an irregularly enhanced rim in the irradiation field . - pubmed
In patients with grade 3 glioma or solitary cerebral metastasis , survival time was definitely dependent upon 201Tl index values , that is , above or below the baseline index of 2.5 . - pubmed
Grade 4 glioma patients , however , had a very short - term survival independent of 201Tl index values . - pubmed
CONCLUSION : Quantitative 201Tl SPECT may be a useful tool for predicting survival of patients with suspected recurrent cerebral tumor and may be used in place of fluorine-18 - 2 - deoxy-2 - fluoro - D - glucose ( 18F - FDG ) scan . - pubmed
Mutagenicity of an organophosphate insecticide acephate -- an in vivo study in chicks . - pubmed
The presented data confirm our earlier reports that the neonatal chicken test system is a convenient model and can be used as an alternative to mammalian systems for screening some environmental contaminants for genotoxicity . - pubmed
We investigated the effect of the selective serotonin reuptake inhibitor citalopram on uncontrolled crying in stroke patients in a double - blind placebo - controlled crossover study . - pubmed
The prognosis was good with only five deaths due to progressive respiratory disease in 48 patients with known follow - up ( 11 % ) . - pubmed
In a double - blind , within - subject , crossover comparison , we recorded visual - evoked potentials ( VEP ) in 30 healthy men during euglycemia and after 20 or 50 min of constant hypoglycemia of 2.66 mM ( 47.9 mg / dl ) induced by HI and PI . - pubmed
Antibodies to human optic nerve in Leber ' s hereditary optic neuropathy . - pubmed
We have analysed serum from 69 LHON patients and their relatives , 58 controls and 14 patients with ischemic or compressive optic neuropathy . - pubmed
Splenic abscess due to Salmonella heidelberg . - pubmed
Human papilloma virus ( HPV)-induced condylomata acuminata in both sexes , as well as cervical dysplasias were treated locally with an ointment or a cream containing 25 mg clomiphene citrate per gram for a fortnight . - pubmed
The therapeutic response to the drug was demonstrated by the disappearance of condylomata acuminata ( 100 % ) , HPV DNA in cervical dysplasia ( up to 80 % ) , and penile genital warts ( 75 % ) . - pubmed
The effect of NAC on mitogen - activated - lymphocyte blastogenesis in C57B1 / 6 mouse splenocytes and ability of NAC to protect lymphocytes against mitogen - induced cytotoxicity was examined in vitro . - pubmed
MRI - derived spinal disc abnormalities were observed in three of the first four asymptomatic volunteer subjects . - pubmed
Growth and growth hormone secretion in children with cancer treated with chemotherapy . - pubmed
RESULTS : Growth hormone deficiency ( GHD ) was observed in 27 of 60 patients ( 45 % ) . - pubmed
CONCLUSIONS : Chemotherapy as the sole form of treatment in children with cancer interferes with growth . - pubmed
Bronchial allergen challenge with isolated major allergens of Dermatophagoides pteronyssinus : the role of patient characteristics in the early asthmatic response . - pubmed
METHODS : In 30 patients with mild - to - moderate asthma , the EAR was investigated after inhalation of an isolated major allergen of Dermatophagoides pteronyssinus ( i.e. - pubmed
CONCLUSION : In asthmatic patients allergic to house dust mites the degree of nonspecific bronchial hyperresponsiveness is the main determinant of early - phase bronchial responsiveness to allergen . - pubmed
In a randomized , controlled trial , 62 patients ( 47 men and 15 women ) with severe antisocial snoring , but no sleep apnea , were allocated to one of three surgical treatments . - pubmed
We report about an unusual case of a rupture of the Achilles tendon in a patient with Haglund ' s exostosis and long term achillodynia . - pubmed
The proteins of 60 KDa showed varied cross reactions against sera of five kinds of patients with other parasitic diseases ( filariasis , hookworm diseases , paragonimiasis , ascariasis and clonorchiasis ) . - pubmed
Several virulence - related genes have been described for prototype enteroaggregative Escherichia coli ( EAEC ) strain 042 , which has been shown to cause diarrhea in human volunteers . - pubmed
This plasmid - borne virulence locus may represent an important set of virulence determinants in EAEC strains . - pubmed
After 6 - hr infusion at 10 mL / kg / hr , a commercial 2.72 % amino acid/7.5 % glucose solution with electrolytes ( AG ) caused obvious phlebitic changes , such as loss of venous endothelial cells , inflammatory cell infiltration , and perivascular edema , in all 6 rabbits because of its low pH ( 4.52 ) and high titratable acidity ( 22 mEq / L ) . - pubmed
Prenatal treatment with methylazoxymethanol ( MAM ) in rats generates animals with a diffuse cortical malformation associated with hyperexcitability . - pubmed
These alterations are reminiscent of the cortical malformations associated with epilepsy in children . - pubmed
We hypothesised that one of the mechanisms supporting hyperexcitability in MAM rats could be the presence of abnormal cortical connections in the malformed cortex . - pubmed
Butyrate and glucose metabolism by colonocytes in experimental colitis in mice . - pubmed
Colonocyte butyrate metabolism was investigated in experimental colitis in mice . - pubmed
A 6.5 - year - old boy presented with thrombocytopenia , Coombs ' positive hemolytic anemia , and multiple small posterior cervical lymph nodes . - pubmed
The typical patient is a middle - aged man with complaints of cough and shortness of breath . - pubmed
Often , the diagnosis is delayed , and patients are treated for asthma or bronchitis . - pubmed
A clone encoding PAH was used for in vitro transcription / translation , followed by immunoprecipitation with sera from 94 APS I patients and 70 healthy controls . - pubmed
Based on subjective evaluation of acne , three subgroups of patients were selected : A ) users where acne improved or disappeared ; B ) users in whom acne deteriorated , C ) users who newly developed acne . - pubmed
In 221 women ( 18.40 % ) , the extent of acne remained unaltered whereas it increased ( subgroup B ) in only 30 women ( 2.50 % ) . - pubmed
The patient died with the clinical signs of pulmonary insufficiency . - pubmed
The correlation between presenting ST - segment depression and the final size of acute myocardial infarcts in patients with acute coronary syndromes . - pubmed
The use of reperfusion therapy in patients with ST elevation acute coronary syndromes had been established . - pubmed
This study of patients with non - ST - elevation acute coronary syndromes investigates the quantitative relationship between presenting ST depression and final QRS changes in both of these subgroups . - pubmed
The data strongly support the concept of graft - host interaction concerning adherence of tumors and extravasation of human melanoma cells . - pubmed
BACKGROUND : Medulloblastoma in late adults ( older than 65 years ) is an exceptional occurrence ; in fact only 8 cases are reported with complete clinical notes in the literature . - pubmed
METHODS : The authors describe a case of medulloblastoma occurring in a 68 - year - old man and analyzed cases reported in the literature . - pubmed
RESULTS : The overall average age of the patients was 72.8 years ( range 67 - 88 years ) , and the male prevalence of this tumour ( 70 % of cases ) seems to be unrelated to age . - pubmed
CONCLUSIONS : It is interesting to note that : 1 ) histological analysis revealed a classic type medulloblastoma ( 88.8 % of cases ) similar to the children : 2 ) site of the tumor is lateral similar to the adults ( 77.7 % of cases ) . - pubmed
Evaluation of the height from which human fell from his / her tissue and organ injuries is discussed . - pubmed
TRANS F may be slightly more hypercholesterolemic than TRANS V or there may be other hypercholesterolemic fatty acids in partially hydrogenated fish oil than those included in the equations . - pubmed
Recombinant vectors based on adeno - associated virus ( AAV ) or human immunodeficiency 1 ( lentivirus ) are promising tools for long term in vivo gene delivery . - pubmed
Managing poor performance non - small - cell lung cancer patients . - pubmed
Glucocorticoids and parental hyperphagia in ring doves ( Streptopelia risoria ) . - pubmed
Collectively , these data support the hypothesis that corticosterone contributes to the parental hyperphagia exhibited by breeding doves during the posthatching period . - pubmed
INTRODUCTION : Accurate staging of the axilla for metastatic disease is critical in deciding on the optimal management of patients with breast cancer . - pubmed
Nontuberculous mycobacterial ( NTM ) infections are an increasingly recognized cause of chronic lung disease in immunocompetent adults , and the M. - pubmed
False - positive magnetic resonance imaging skeletal survey in a patient with sporadic hypophosphatemic osteomalacia . - pubmed
[ Integral indices of peripheral blood leukogram in the estimation of non - specific immunological reactivity in patients with ischemic heart disease ] . - pubmed
With the help of differential blood count analysis and velocity of erythrocyte sedimentation ( VES ) , 30 healthy persons ( donors ) , 30 patients with chronic ischemic hearty disease ( IHD ) and 34 patients with acute myocardial infarction ( AMI ) underwent the procedure of calculation for leukocyte index ( LI ) , leukocyte intoxication index ( LII ) , leukocyte shift index ( LSI ) , leukocyte and VES ratio ( LVESR ) , leukocytic and granulocytic index ( LGI ) , general index ( GI ) , neurophil - lymphocyte ratio ( NLR ) , neurophil - monocyte ratio ( NMR ) , lymphocyte - monocyte ratio ( LMR ) and lymphocyte - eosinophil ratio ( LER ) . - pubmed
METHOD : The stance phase from heel - contact to toe - off of normal walking gait and after tibialis posterior tendon rupture was simulated in eight roentenographically normal human feet ( age 66 + /- 19 years , males ) . - pubmed
EXPERIMENTAL DESIGN : Two ml of peripheral blood were collected from 55 cases with hepatocellular carcinoma ( HCC ) , 20 cases with chronic liver diseases devoid of cancer , and 20 healthy volunteers . - pubmed
Cardiac transplantation has emerged as the therapeutic procedure of choice for patients with end - stage heart disease but the availability of donor organs remains major limiting factor allowing only 1 % of the candidates actually become transplant recipients . - pubmed
The aim of this report is to summarize other currently available therapeutic alternatives for patients with end - stage cardiac disease . - pubmed
[ Sequelae of resection of cervical sympathetic nerves in dogs with unilateral irritation of the diencephalon ] . - pubmed
[ Action of histamine on the tracheal cytograms of mice subjected to influenza infection ] . - pubmed
[ Non - specific mesadenitis in children ] . - pubmed
On some problems arising from the observation of the infection with Plasmodium berghei in mice and rats . - pubmed
AIDS is one of the greatest infectious disease threats to human health despite the extensive efforts made since the discovery of HIV in 1983 . - pubmed
The use of plasmid DNA vaccination to elicit humoral and cell - mediated immune responses against HIV infection has produced promising results in animal and in human trials . - pubmed
METHODS : 65 patients with BD , 27 with rheumatic diseases with vasculitis , and 80 controls were studied . - pubmed
Adverse mortality effect of central sympathetic inhibition with sustained - release moxonidine in patients with heart failure ( MOXCON ) . - pubmed
SALT - FREE and rice diets for hypertension . - pubmed
Recapitulation of B cell differentiation in the central nervous system of patients with multiple sclerosis . - pubmed
Although technical advances in the treatment of the elderly have resulted in improved fracture fixation and surgical outcomes , clinical pathways have been developed to further improve patient outcome while shortening hospital length of stay after hip fracture . - pubmed
We report on three boys , two brothers and their maternal cousin , presenting with dry hair , pilar keratosis , severe hypodontia , smooth tongue , onychodysplasia , and keratoderma and hyperhidrosis of palms and soles . - pubmed
Although effective in inducing tumor - specific immunity in mice and in some clinical trials , tumor - derived HSPs have many limitations like vaccines , such as the technical difficulty of ex vivo preparation of adequate quantities of HSPs from the resected tumors of individual patients . - pubmed
Our findings may have broad relevance to the use of the in vivo HSP / suicide gene tumor vaccine in therapy for human solid tumors . - pubmed
PURPOSE : The purpose of this research was to generate a human monoclonal antibody specific to gynecological cancers and to evaluate such an antibody as therapy for gynecological cancers . - pubmed
EXPERIMENTAL DESIGN : Transchromosomal KM mice were immunized with the human uterine endometrial cancer cell line SNG - S. - pubmed
Hybridomas were constructed between spleen cells from KM mice and mouse myeloma cells . - pubmed
Performance of children diagnosed with ADHD on selected planning and reconstitution tests . - pubmed
Endothelial calcium signaling in rabbit arteries and its local alterations in early - stage atherosclerosis . - pubmed
This study is to examine whether endothelial calcium signaling is different between atherosclerosis - prone thoracic aortas ( TA ) and atherosclerosis - resistant carotid arteries ( CA ) in normal rabbits and how it changes in early - stage atherosclerosis . - pubmed
In the same hypercholesterolemic animal , fatty streak formation was much more prominent in TA than in CA . - pubmed
Cessation of smoking after AMI was associated with a significantly lower risk of cardiac events in patients with MS ( HR 0.485 , 95 % CI 0.281 to 0.837 , p=0.009 ) but not in patients without MS ( HR 0.618 , 95 % CI 0.330 to 1.157 , p=0.132 ) . - pubmed
The first was a 78 - year old woman who had a 2 - d history of vomiting and epigastralgia . - pubmed
The second case was a 76 - year old man with a 1 - wk history of epigastralgia . - pubmed
The procedure for the localization of fMRI areas was validated by direct cortical stimulation on 38 AVM and tumor patients undergoing conventional surgery . - pubmed
Indications for the procedure were DVT or PE and contraindication of anticoagulation in 141 patients ( 49.1 % ) , DVT or PE and complication of anticoagulation in 65 patients ( 22.6 % ) , prophylaxis in 39 patients ( 13.6 % ) , massive PE or poor respiratory function in 31 patients ( 10.8 % ) , paradoxal emboli in 4 patients ( 1.4 % ) and other causes in seven patients . - pubmed
Symptomatic recurrent PE occurred in 6 patients ( 2.1 % ) and was the cause of death on 3 of them ( 1 % ) , DVT has been detected in 22 patients ( 7.7 % ) during the follow up period . - pubmed
INTRODUCTION AND OBJECTIVES : In patients with pulmonary atresia with intact ventricular septum ( PAIVS ) , radiofrequency - assisted perforation of the valve is the most widely used initial therapy when the anatomy is favorable . - pubmed
infection in owl monkeys ( Aotus nancymae ) . - pubmed
pinworms in Aotus nancymae and other New World primates are typically subclinical , but infection during experimental use could confound interpretation of experimental data . - pubmed
Here , we report on a specific prognostic study on stroke patients and describe how we explored the prediction performance of our model . - pubmed
Combined effects of hypoxia and endurance training on lipid metabolism in rat skeletal muscle . - pubmed
METHODS : Male Wistar rats were exposed either to hypobaric hypoxia ( at a simulated altitude of approximately 4000 m , PIO(2 ) approximately 90 mmHg ) or to normoxia ( sea level ) for 5 weeks . - pubmed
Iodine is an essential nutrient for humans as a critical constituent of thyroid hormones ; both iodine deficiency and excess have adverse consequences for the thyroid gland . - pubmed
Seven patients with acute optic neuritis and two patients with acute stroke were investigated . - pubmed
RESULTS : The mean perfusion value for ROIs in gray matter was 62 mL/100g / min and 21 mL/100g / min in white matter in patients with acute optic neuritis . - pubmed
The perfusion inside the infarct core was 9 mL/100g / min in one of the stroke patients . - pubmed
RATIONALE : Exploring differences between mouse strains in drug effects in models of antidepressant - like activity may provide clues to the neurobiology of antidepressant responses . - pubmed
C57Bl/6 mice were more sensitive to 8 - OH - DPAT - induced hypothermia . - pubmed
Real - life effectiveness of Singulair ( montelukast ) in 506 children with mild to moderate asthma . - pubmed
OBJECTIVES : To assess the efficiency of and satisfaction with Singulair in asthmatic children under real - life conditions . - pubmed
METHODS : Montelukast was prescribed for 6 weeks to a cohort of 506 children aged 2 to 18 years with mild to moderate persistent asthma , who were enrolled by 200 primary care pediatricians countrywide . - pubmed
High rate of abortion and developmental abnormalities is thought to be closely associated with inefficient epigenetic reprogramming of the transplanted nuclei during bovine cloning . - pubmed
PURPOSE : To study the reduction in tumor size and the safety and efficacy of combined phacoemulsification and intravitreal triamcinolone acetonide injection ( phaco - IVTA ) in patients with treated melanoma and atypical nevi . - pubmed
METHODS : The medical records of 49 consecutive patients ( 51 eyes ) with treated melanoma or atypical nevi treated with phaco - IVTA were evaluated retrospectively for changes in Snellen visual acuity , tumor volume , and frequency of complications . - pubmed
CONCLUSIONS : Combined phacoemulsification and IVTA was reasonably safe in patients with treated melanoma and atypical nevi . - pubmed
Intravitreal triamcinolone acetonide injection at the time of cataract surgery in patients with treated melanoma or nevus may reduce rates of tumor progression in these patients . - pubmed
Detection and description of spatial patterns of bacterial brown spot of snap beans using cyclic samples . - pubmed
[ Successful functional hemispherectomy in adult patients with refractory epilepsy ] . - pubmed
METHODS : We report our series of four adult patients that have undergone functional hemispherectomy for their refractory epilepsy . - pubmed
One patient had Rasmussen encephalitis . - pubmed
The fourth patient has had more than 75 % reduction in seizure frequency . - pubmed
Early complications included an isolated tonic - clonic generalized seizure ( one patient ) , and status epilepticus in another patients related to infection and use of meropenem . - pubmed
Only one patient has presented hemianopia as a permanent neurological deficit after surgery . - pubmed
CONCLUSIONS : Functional hemispherectomy is a good surgical option in the setting of large unilateral hemispheric lesions causing hemiparesis and intractable seizures , even in adult patients . - pubmed
Several studies indicate that testosterone replacement therapy may produce a wide range of benefits for men with hypogonadism , including improvement in libido , bone density , muscle mass , body composition , mood , and cognition . - pubmed
Time course of continuous positive airway pressure effects on central sleep apnoea in patients with chronic heart failure . - pubmed
Continuous positive airway pressure ( CPAP ) causes a variable immediate reduction in the frequency of central apnoeas and hypopnoeas in patients with congestive heart failure ( CHF ) and central sleep apnoea ( CSA ) , but has beneficial mid - term effects on factors known to destabilize the ventilatory control system . - pubmed
Preoperative use of inhaled tiotropium in lung cancer patients with untreated COPD . - pubmed
BACKGROUND AND OBJECTIVE : Lung cancer patients with COPD are at high risk during surgery . - pubmed
METHODS : A retrospective review was performed of the medical records of 102 patients with primary lung cancer and COPD , who underwent scheduled surgery . - pubmed
Twenty - one lung cancer patients with untreated mild - to - severe COPD received tiotropium preoperatively . - pubmed
CONCLUSIONS : Preoperative treatment with tiotropium may facilitate surgical treatment for lung cancer patients with COPD . - pubmed
This is encouraging for COPD patients who may require curative lung resections . - pubmed
However , pain - dependent immobilization may pose a serious hazard to patients with severe preexisting co - morbidities . - pubmed
METHODS : We retrospectively analysed 534 patients with these injuries . - pubmed
Notably eight patients presented with meningitis . - pubmed
Fifteen patients ( 42.8 % ) had inclusion tumor with the dermoid tumor being the most common . - pubmed
Human - in - mouse modeling of primary head and neck squamous cell carcinoma . - pubmed
METHODS : HNSCC tissue was obtained from patients at biopsy / resection , cultured , and implanted into mice . - pubmed
Histology and immunohistochemistry ( IHC ) were used to confirm HNSCC and human origin . - pubmed
Xenograft modeling was attempted in primary HNSCCs from 12 patients with a success rate of 92 % . - pubmed
Immunostaining confirmed human origin of epithelial tumor cells within the modeled tumor . - pubmed
The high success rate of human - in - mouse tumor formation from primary HNSCC suggests that selection pressures for tumor growth in this model may be less than those observed for establishment of cell lines . - pubmed
Contrary to our hypothesis , these results suggest that endurance training induced significant impairment of regional systolic and diastolic LV myocardial function and ejection fraction in rats . - pubmed
There is virtually no literature on physiological changes in the brains of children or adults with cerebral palsy ( CP ) after an intervention . - pubmed
It is unclear whether the principles of plasticity that have been deduced from animal models of stroke might also apply to children and adults with CP . - pubmed
But children with CP should have the potential to respond to experience in a similar way to adults , with the additional potential of regulation of neuronal development in response to injury . - pubmed
PURPOSE : To determine the magnitude of setup and organ motion errors from a subset of prostate cancer patients treated with conventional conformal radiotherapy , and to estimate the CTV - PTV margin according to published margin recipes . - pubmed
METHODS AND MATERIALS : Twenty prostate cancer patients were treated with external radiotherapy using electronic portal images ( EPIs ) . - pubmed
The infection is either not transmitted at all or only under exceptional conditions by turkeys in the early acute stage . - pubmed
A few coccidia cysts were found in two turkeys and are referred to more in detail elsewhere . - pubmed
nicotinamide , lactic acid , triethyl acetate / ethyllineolate , and prebiotic plant extracts , affect different mechanisms of acne pathogenesis and therefore may contribute to a decrease in acne lesions . - pubmed
Soy Bowman Birk Inhibitor Concentrate ( BBIC ) is a known cancer preventive agent now in human clinical trials . - pubmed
In a xenograft model of nude mice transplanted with human breast cancer MDA - MB-231 cells , intraperitoneal injections of lunasin , at 20 mg / kg and 4 mg / kg body weight , decrease tumor incidence by 49 % and 33 % , respectively , compared with the vehicle - treated group . - pubmed
CONCLUSIONS / SIGNIFICANCE : We conclude that lunasin is actually the bioactive cancer preventive agent in BBIC , and BBI simply protects lunasin from digestion when soybean and other seed foods are eaten by humans . - pubmed
israelensis ( Bti , H-14 serotype ; VectoBac ( ) WDG ) in the laboratory and also in the field against two principal malaria vectors , Anopheles culicifacies and Anopheles stephensi . - pubmed
The respiratory syncytial virus ( RSV ) is a primary cause of lower respiratory tract infections in children , the elderly and in people who are immune suppressed , and is also the cause for the development of asthma primarily in infants . - pubmed
However , the immunological mechanisms by which RSV enhances allergic sensitization and asthma remain unclear . - pubmed
We investigated the frequency of CADASIL among selected patients with cerebral ischemia of the lacunar subtype . - pubmed
METHODS : we studied patients under 65 years old who presented cerebral ischemia of the lacunar subtype without hypertension , diabetes mellitus or other causes that explained the cerebral ischemia . - pubmed
We studied 30 patients , mean age was 53 years ( range 34 to 65 ) , 50 % were men and all patients suffered a lacunar stroke . - pubmed
Immunostaining analysis was positive in two patients ( 6.6 % ) and the genetic analysis confirmed a mutation characteristic of CADASIL in exon 4 nt 622C / T ( Arg 182 Cys ) and 694 T / C ( Cys206Arg ) respectively . - pubmed
CONCLUSIONS : CADASIL disease was present in 6.6 % of patients younger than 65 years with a lacunar stroke and without hypertension or diabetes mellitus . - pubmed
Screening for CADASIL should be considered in these patients . - pubmed
To help uncover the functional significance of macrophages in the context of trypanosome infection , we determined the mRNA levels of genes associated with an increase in macrophage number or macrophage function in WS- and ILS - infected rats and in cultured cells . - pubmed
Anemia occurs in ILS- , but not WS - infected , rats . - pubmed
These results suggest that anemia - induced hypoxia in ILS - infected rats stimulates the immune system and activates macrophages . - pubmed
Carboplatin and gemcitabine combination in metastatic triple - negative anthracycline- and taxane - pretreated breast cancer patients : a phase II study . - pubmed
The carboplatin and gemcitabine ( CG ) combination is active in unselected anthracycline / taxane pretreated metastatic breast cancer patients , so we carried out a phase II study to evaluate the activity of the CG combination in pretreated metastatic TNBC patients . - pubmed
Grade 3/4 neutropenia occurred in 17 and febrile neutropenia in 4 patients . - pubmed
Ten patients had Grade 3/4 thrombocytopenia . - pubmed
The CG combination is a reasonable option for the treatment of metastatic pretreated TNBC patients . - pubmed
OBJECTIVE : Our goal was to determine the prevalence of sexual dysfunction and identify risk factors associated with sexual morbidity in patients with early stage endometrial cancer . - pubmed
METHODS : This prospective trial included patients with stage I - IIIa endometrial cancer , without evidence of disease , and one to five years out from primary surgical treatment . - pubmed
Novel anti - cancer role of naphthazarin in human gastric cancer cells . - pubmed
This study is the first to investigate the anti - cancer effect of naphthazarin ( Naph ) , one of the naphthaquinones , in human gastric cancer AGS cells . - pubmed
Treatment reduces the cryoglobulins that cause vasculitis , yet it also leads to a transient increase in liver enzymes and HCV genomic RNA in the periphery . - pubmed
RESULTS : Sixteen patients ( 15.5 % ) developed DAIIS with the need for surgical intervention . - pubmed
Aging independently of the hormonal status changes pain responses in young postmenopausal women . - pubmed
The objective was to determine the efficacy and safety of dexamethasone ointment in the treatment of recurrent aphthous ulceration and detect serum dexamethasone concentrations in the patients . - pubmed
There were 810 patients with minor recurrent aphthous ulcerations screened for study eligibility , and 240 patients were enrolled at 5 centers from March 1 , 2009 to April 30 , 2010 ; 120 were assigned randomly to the treatment group and 120 to a control group . - pubmed
Patients were instructed to apply the given agent to the identified ulcer 3 times a day ( after meals ) for 5 days . - pubmed
Structured multidisciplinary management enables it to be performed safely even in patients with a PM or ICD . - pubmed
BACKGROUND : Previous studies demonstrated that high fruit consumption was associated with a lower risk of cardiovascular events in patients with Type 2 diabetes mellitus . - pubmed
We studied the relationship between dietary fruit intake and carotid intima - media thickness in patients with Type 2 diabetes . - pubmed
METHODS : A total of 255 Chinese patients with Type 2 diabetes were recruited . - pubmed
The method is demonstrated on both simulated and in vivo short - TE 1H MRSI data in patients with GBM . - pubmed
In addition , mice bearing HCT-8 - xenografted tumors , which received intratumoral administration of the oncolytic adenovirus , showed significantly reduced tumor growth and enhanced survival . - pubmed
RESULTS : For full thickness rotator cuff tears , MRI and arthroscopy detected them in 76 and 82 patients , respectively . - pubmed
Clinical outcomes of patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesions . - pubmed
BACKGROUND : We compared clinical outcomes between patients with salivary gland carcinomas preoperatively misdiagnosed as benign lesion and properly diagnosed as malignant lesion . - pubmed
CONCLUSIONS : The clinical outcomes of patients with salivary gland carcinomas misdiagnosed as benign are relatively favorable . - pubmed
Hemiarthroplasty of the shoulder can be a safe and an effective treatment for pain in patients with rheumatoid arthritis . - pubmed
We report a patient who presented with a discharging sinus over the tip of the acromium which was created by the displacement of the prosthesis and erosion of the AC joint and distal clavicle . - pubmed
Implication of limonene and linalyl acetate in cytotoxicity induced by bergamot essential oil in human neuroblastoma cells . - pubmed
Bergamot ( Citrus bergamia , Risso et Poiteau ) essential oil ( BEO ) is a widely used plant extract showing anxiolytic , analgesic and neuroprotective effects in rodents ; also , BEO activates multiple death pathways in cancer cells . - pubmed
Psychosis and E. - pubmed
Spraque - Dawley rats with bile duct ligation ( BDL)-induced cirrhosis received vehicle ( citrate buffer ) or streptozotocin ( diabetic , BDL / STZ ) . - pubmed
The survival rate of cirrhotic rats was decreased by STZ injection . - pubmed
OBJECTIVES : The current study evaluated whether the functional connectivity pattern of the thalamo - cortical network in patients with Alzheimer ' s disease ( AD ) and mild cognitive impairment ( MCI ) would show disease severityrelated alterations . - pubmed
Second , the MCI subjects were included to evaluate how different stages of disease affect the functional connectivity pattern of the thalamus . - pubmed
Finally , a correlation analysis was performed between the strength of the functional connectivity of the identified regions and various clinical variables to evaluate the relationship between the strength of functional connectivity and the cognitive abilities of MCI and AD patients . - pubmed
Functional connectivity between the bilateral thalamus and the identified brain regions of MCI subjects was intermediate in comparison to the functional connectivity of AD and NC subjects . - pubmed
CONCLUSION : Our results revealed disease severity - related alterations of the thalamo - default mode network and thalamocortical connectivity in AD and MCI patients . - pubmed
Values of IC50 were calculated for complexes 3 and 4 against a panel of human tumor cell lines representative of ovarian ( A2780 and A2780cis ) and breast cancers ( T47D ) . - pubmed
This could lead to mood disorders or altered response to any behavior influenced by estradiol in humans . - pubmed
Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients . - pubmed
The objective of this study was to perform comprehensive analysis of lipids in breast cancer patient serum samples . - pubmed
Lipidomic profiling using an established analytical platform was performed in two cohorts of breast cancer patients receiving neoadjuvant chemotherapy . - pubmed
The results suggest that the altered serum levels of oleic acid in breast cancer patients are associated with their response to chemotherapy . - pubmed
Serologic tests for antibodies to Blastomyces dermatitidis are not thought to be useful for the diagnosis of blastomycosis , in part due to the low sensitivity of immunodiffusion and complement fixation . - pubmed
dermatitidis surface protein BAD-1 were used for testing sera from patients with proven blastomycosis or histoplasmosis and controls . - pubmed
The antibodies were detected in 87.8 % of the patients with blastomycosis by the enzyme immunoassay compared to 15.0 % by immunodiffusion . - pubmed
METHODS : Intracranial injection of the neurotoxin 6 - hydroxydopamine ( 6 - OHDA ) was selectively lesioned into the nigrostriatal dopaminergic pathway in adult Sprague Dawley rats , which is a common rat model of PD . - pubmed
Caudal vertebral body fractures following lateral interbody fusion in nonosteoporotic patients . - pubmed
However , vertebral body fractures have been reported after this procedure , particularly in patients with osteoporosis and patients undergoing multilevel fusions . - pubmed
We evaluated the risk factors for caudal vertebral body fractures in 2 nonosteoporotic patients with single - level disease . - pubmed
CASE REPORTS : Two patients presented with several years ' history of incapacitating chronic low back pain and intermittent radicular pain . - pubmed
Both patients returned several weeks later with excruciating low back pain , without any postoperative history of trauma or heavy lifting . - pubmed
Diagnostic imaging in both patients showed a coronal fracture of the inferior vertebral body . - pubmed
CONCLUSION : Caudal vertebral body fracture in patients with normal bone quality is a major potential complication after the minimally invasive lateral approach for lumbar fusions . - pubmed
The results suggest that older people present a heterogeneous olfactory loss more specific to heavier molecules . - pubmed
RESULTS : A 36 - year - old woman at 14 weeks of gestation was admitted to the hospital for management of severe hyperemesis gravidarum ( HG ) . - pubmed
Physical examination revealed a confused , lethargic woman with a normal - size thyroid and pendular nystagmus in primary and lateral gaze . - pubmed
CONCLUSION : This case demonstrates that gestational thyrotoxicosis in a patient with HG can precipitate acute WE , which may mimic thyroid storm and thus delay appropriate management of this neurologic disorder . - pubmed
We conclude that prophylactic thiamine administration may be considered before caloric replacement in patients who present with HG and acute neurologic dysfunction . - pubmed
Evaluation of the effect of tranilast on rats with spinal cord injury . - pubmed
We evaluated its ability to improve motor function and inhibit the spread of tissue damage in rats with SCI . - pubmed
The effect of vagus nerve stimulation on CSF monoamines and the PTZ seizure threshold in dogs . - pubmed
BACKGROUND : Vagus nerve stimulation ( VNS ) is an established treatment for refractory epilepsy in humans , but the precise mechanism of action ( MOA ) , predictive responsive factors and the optimal stimulation parameters remain to be elucidated . - pubmed
One hour of VNS did not affect seizure threshold in the canine PTZ model . - pubmed
The objective of this study was to examine whether reduced inflammation is a possible mechanism for postoperative cognitive improvement in bariatric surgery patients . - pubmed
RESULTS : Patients exhibited preoperative cognitive impairment , although improvements 1 year postsurgery were seen in both attention / executive function ( mean [ M ; standard deviation { SD}]baseline = 53.57 [ 8.68 ] versus M ( SD)follow - up= 60.32 [ 8.19 ] ) and memory ( M [ SD]baseline= 44.96 [ 7.98 ] versus M [ SD]follow - up= 51.55 [ 8.25 ] ) . - pubmed
Myiasis is a pathologic condition in humans occurring because of parasitic infestation . - pubmed
CONCLUSIONS : HFRS patients have increased thrombopoiesis and platelet activation , which contributes to intravascular coagulation . - pubmed
BACKGROUND : Statin use in individuals with chronic obstructive pulmonary disease ( COPD ) with coexisting cardiovascular disease is associated with a reduced risk of exacerbations . - pubmed
These findings may ultimately lead to new and novel therapeutic targets for patients with COPD . - pubmed
Human resting T - lymphocytes , T - lymphoblasts , and the leukemic Jurkat T - cells all exhibit membrane rupture above a critical membrane area expansion that is independent of either micropipette size or aspiration pressure . - pubmed
METHODS : Ninety - nine consecutive patients diagnosed and treated for infectious SD between January 2007 to May 2015 were reviewed retrospectively . - pubmed
We herein report the case of a 63 - year - old female admitted to the hospital for ST elevation myocardial infarction . - pubmed
Clinical , radiological and biological findings oriented to a pneumopathy and the patient received the treatment for it . - pubmed
A national retrospective study of paediatric end - stage liver disease as a predictor of change to second - line therapy in children with autoimmune hepatitis . - pubmed
METHODS : One hundred and seventy - one children from 13 Canadian centres who fulfilled the International Autoimmune Hepatitis Group ( IAIHG ) criteria were included and assessed for change to second - line therapy within 24 months of primary treatment onset . - pubmed
Thrombocytosis in a patient with upper gastrointestinal bleeding . - pubmed
Early - stage left atrial intramural hemorrhage mimicking partial coronary sinus thrombosis in a patient who received ablation for atrial tachyarrhythmias . - pubmed
Human scabies ( infestation with the mite Sarcoptes scabiei var hominis ) causes a significant disease burden worldwide , yet there are no agreed diagnostic guidelines . - pubmed
Eligible studies were trials of therapeutic interventions against scabies in human subjects , published in English , enrolling patients with scabies , and using various therapeutic interventions . - pubmed
The validity of this observation is supported by an effect largely confined to those patients with a dilated pancreatic duct . - pubmed
The nutritional status of patients undergoing PD for cancer needs further investigation and the effects of PERT require verification in further clinical studies . - pubmed
We present a 68 - year - old patient with multiple primary infiltrative BCCs in the scalp area , initially treated 14 years ago with superficial contact X - ray therapy , end dose 60 greys , followed by electrocautery ( x2 ) several years later . - pubmed
A 32 - year - old man sustained an isolated perforation of the gallbladder following blunt abdominal trauma . - pubmed
METHODS : Lymphoma events ( up to March 2015 ) were identified from 19 tofacitinib studies ( 2 phase I , 9 phase II , 6 phase III , and 2 long - term extension ) of patients with moderate to severe RA . - pubmed
Lymphoma incidence rates ( IRs ; number of patients with events/100 patient - years ) and standardized incidence ratios ( SIRs ) were calculated . - pubmed
CONCLUSION : In the tofacitinib RA clinical development program , lymphoma rates were stable over time and there were minimal differences in the baseline characteristics of patients with and without lymphoma . - pubmed
BACKGROUND : This study aimed to identify the clinical predictors of the degree of right ventricular ( RV ) myocardial fibrosis in patients with repaired tetralogy of Fallot ( TOF ) with special focus on the RV pressure load . - pubmed
Methods and Results : From April 2004 to March 2017 , 30 patients with repaired TOF underwent pulmonary valve replacement and concomitant RV myocardial biopsy . - pubmed
Patients with a right - to - left ventricular systolic pressure ratio & gt;0.45 showed a significantly greater degree of RV myocardial fibrosis under an equivalent stroke volume ratio . - pubmed
CONCLUSIONS : Under conditions of RV volume overload , a right - to - left ventricular systolic pressure ratio & gt;0.45 was a predisposing factor for progression of RV myocardial fibrosis in patients with repaired TOF . - pubmed
pylori ) is one of the most prevalent human pathogen and a persistent infection with this bacterium causes common pathologies , such as gastritis or peptic ulcers , and also less common but more serious pathologies , such as gastric cancer or gastric mucosa - associated lymphoid tissue ( MALT ) lymphoma . - pubmed
The clinical outcome of gastrointestinal infection sustained by H. - pubmed
It has been documented that Th1 , Th2 , Th9 , Th17 , Th22 and T regulatory ( Treg ) cells , separately or in coordination with each other , can affect the outcome of the infection sustained by of H. - pubmed
Findings : Thirty patients aged & gt;= 60 years undergoing a radical operation of oral malignant tumors with tissue reconstruction ( & gt;= 8 h ) were analyzed . - pubmed
Titanium TSME appliance for patients allergic to nickel . - pubmed
CONCLUSION : The non - allergic properties of titanium allow to propose it as an alternative in patients with a long - term history of allergic reactions to nichel . - pubmed
Here we study independent and interactive effects of cognitive regulation ( inhibition and sustained attention ) , temperament ( reactive and regulatory aspects ) , and maternal sensitivity ( as external regulation ) in a sample of 112 typically developing 10 - month - old infants ( 59 boys , 52.7 % ) , in relation to inattentive and hyperactive / impulsive behavior at 3 years . - pubmed
Complications of pelvic and acetabular fractures in 1331 morbidly obese patients ( BMI & gt;= 40 ): a retrospective observational study from the National Trauma Data Bank . - pubmed
Conclusions : Morbidly obese patients had higher rates of complications and longer hospital stays and were more likely to be discharged to rehabilitation facilities compared with control patients after pelvic ring or acetabular fracture . - pubmed
The ITS1 based geographical distribution studies indicated detection of environmental sequences similar ( 93 - 96 % ) to this strain from cattle faeces . - pubmed
Differential proteomic analysis to identify proteins associated with beak deformity in chickens1 . - pubmed
The beak is the dominant avian facial feature , and beak deformity occurs in 0.5 to 2.5 % of some indigenous chicken breeds , resulting in difficulties when eating , drinking , and performing natural behaviors . - pubmed
A density model of neurovascular structures was generated from 28 human vastus lateralis muscles isolated from embalmed cadavers . - pubmed
In this report , we describe an extremely rare case of a patient who suffered from vertebral osteomyelitis caused by Peptostreptococcus micros . - pubmed
Case Report : A 73 - year - old man with a history of diabetes mellitus was admitted to our hospital with a 5 - month history of severe low back pain . - pubmed
Effect of Electroacupuncture on Spermatogenesis in Rats with Oligozoospermia of Insufficiency of Shen ( Kidney ) Essence Syndrome . - pubmed
OBJECTIVE : To assess the effect of electroacupuncture ( EA ) on expression of cytoskeletal proteins from Sertoli cells ( SCs ) and spermatogenesis in rats with oligozoospermia of insufficiency of Shen ( Kidney ) essence syndrome ( OIKES ) . - pubmed
Reference tables with centiles of limb to body height ratios of healthy human adults for assessing potential thalidomide embryopathy . - pubmed
Until nearly 30 years later in 1988 there were already over 10.000 children born with severe birth defects ( e.g. - pubmed
OBJECTIVES : We hypothesized that non - lytic rifampicin compared with lytic beta - lactam antibiotic treatment would attenuate the inflammatory response in patients with pneumococcal pneumonia . - pubmed
RESULTS : Forty - one patients with community - acquired pneumonia were included ; 17 of them had pneumococcal pneumonia . - pubmed
Cytotoxicity test of film extracts was conducted with L929 mouse fibroblasts , and the relative growth rate approached or exceeded 75 % , indicating an acceptable cytocompatibility . - pubmed
How cancer - specific mortality changes over time after radical cystectomy : Conditional survival of patients with nonmetastatic urothelial carcinoma of the urinary bladder . - pubmed
METHODS AND MATERIALS : Within the SEER database ( 2004 - 2015 ) , we identified pTa / pTis / pT1N0 high grade , pT2 to pT4N0 and pTanyN1 - 3 patients treated with radical cystectomy for nonmetastatic urothelial carcinoma of urinary bladder . - pubmed
Methods : A total of 118 consecutive patients with CAVS were enrolled in the study ; 35 individuals without aortic valve calcification were included in the control group . - pubmed
Conclusion : The method to quantify CX1003 in human plasma was first exploited and validated with good sensitivity and specificity , and successfully fulfilled the requirement of the first - in - human clinical pharmacokinetic study of CX1003 in Chinese patients with relapsed or metastatic malignant solid tumors . - pubmed
BVD in sheep flocks . - pubmed
Bilateral Basal Ganglia Lesions in a Dialytic Patient with Diabetes and Recurrent Hypoglycemia . - pubmed
External Validation of Pretreatment Pathological Tumor Extent in Patients with Neoadjuvant Chemoradiotherapy Plus Surgery for Esophageal Cancer . - pubmed
METHODS : Patients with esophageal cancer treated with neoadjuvant chemotherapy and esophagectomy between 2012 and 2015 were included . - pubmed
Cell therapy stimulates bone neoformation in calvaria defects in rats subjected to local irradiation . - pubmed
Background : The purpose of the study was to analyze the effect of cell therapy on the repair process in calvaria defects in rats subjected to irradiation . - pubmed
Patients were followed for eight weeks after discharge for relapse . - pubmed
RESULTS : Over a 2 - year period , 215 patients developed nosocomial CDI ( incidence 2:1000 ) and 200 ( mean age 62.2 + -19.6 years ) gave informed consent . - pubmed
Recurrence occurred in 43 patients ( 21.5 % ) . - pubmed
Changes in Cuticle Components and Morphology of ' Satsuma ' Mandarin ( Citrus unshiu ) during Ambient Storage and Their Potential Role on Penicillium digitatum Infection . - pubmed
To elucidate the role of fruit cuticle in fungal infection , changes in cuticle composition and morphology of ' Satsuma ' mandarin during ambient ( at 25 C ) storage and their role in Penicillium digitatum infection were investigated . - pubmed
METHODS : We reviewed all patients who underwent LTHE with extended lymph node dissection for distal esophageal adenocarcinoma ( EAC ) at our institution between 2007 and 2016 . - pubmed
Pre - operative characteristics , operative details , postoperative complications , and long - term outcomes were tracked by review of the electronic medical record and patient surveys . - pubmed
CONCLUSIONS : Laparoscopic transhiatal esophagectomy has an important role in current esophageal cancer treatment and can be performed with curative intent in patients with distal esophageal tumors . - pubmed
We aimed to explore the determinants of endothelial - dependent and -independent microvascular function progression over a 3 year period , in people with and without both diabetes and few clinical microvascular complications . - pubmed
METHODS : Demographics were collected in 154 participants with type 2 diabetes and in a further 99 participants without type 2 diabetes . - pubmed
RESULTS : People with type 2 diabetes had impaired endothelial - dependent microvascular response compared with those without ( AUC 93.9 [ 95 % CI 88.1 , 99.4 ] vs 111.9 [ 102.3 , 121.4 ] arbitrary units [ AU ] x min , p < 0.001 , for those with vs without diabetes , respectively ) . - pubmed
METHODS : Consecutive patients with atrophic gastritis or known GIM were prospectively included . - pubmed
Higher proportions of patients with GIM were detected by OE and acetic acid versus random biopsy ( 60.5 % vs 35.5 % , 67.1 % vs 31.5 % , respectively ; P < 0.0001 for both comparisons ) . - pubmed
A 58 - year - old man is brought by the ambulance to the emergency department ( ED ) of a tertiary care centre following an out - of - hospital cardiac arrest . - pubmed
The electromagnetic radiation generated from mobile phones , radio - based stations , and phone towers , high - voltage power lines have been reported which leads to the variety of health scares such as the risk of cancer in human beings and adverse effects in animals , birds , etc . - pubmed
As school districts across the United States consider how to safely operate during the 2020 - 21 academic year , CDC recommends mitigation strategies that schools can adopt to reduce the risk for transmission of SARS - CoV-2 , the virus that causes coronavirus disease 2019 ( COVID-19 ) ( 1 ) . - pubmed
Further , patients ` characteristics were compared between benign and malignant parotid lesions and between the two most common malignant parotid lesions . - pubmed
Out of 777 patients , 614 ( 78.9 % ) patients had a benign and 164 ( 21.1 % ) patients had a malignant parotid lesion . - pubmed
Patients with metastatic cSCC were significantly older ( p < 0.001 ) and significantly more likely to be male ( p < 0.001 ) than patients with primary parotid malignancies . - pubmed
The present study shows the high prevalence of secondary parotid malignancies in patients who had received parotidectomy . - pubmed
Ishigamide was isolated as a metabolite of a recombinant strain of Streptomyces sp . - pubmed
METHODS : We performed a retrospective review of 107 patients diagnosed with plantar fasciitis who underwent ultrasound - guided release of the plantar fascia . - pubmed
RESULTS : Heel pain improved in 92.5 % ( 99 ) of patients , but not in 7.4 % ( 8 patients ) . - pubmed
In the group of patients whose heel pain improved , 9 experienced overload on the lateral column and dorsum of the foot , which improved with the use of plantar orthoses and a rehabilitation program . - pubmed
One male narcolepsy - cataplexy patient was placed on the 60 - 30 schedule for 48 h. All subjects showed REM sleep during the schedule manipulation . - pubmed
Pulmonary infection with capsule - deficient cryptococcus neoformans . - pubmed
A case of bilateral lobar pneumonia due to Crytococcus neoformans is presented . - pubmed
In diabetic animals there was no response over the 15 - min time period studied . - pubmed
In cats , horizontally transmitted viruses cause leukemia and lymphoma under natural conditions . - pubmed
FOCMA , which is FeSV - coded , is transformation and/or tumor specific and expressed regardless of whether or not the cells make virus or contain virus structural antigens . - pubmed
Lymphoid leukemia cells also express FOCMA , both when FeLV is used to induce the disease in laboratory cats and when the tumors occur under natural conditions . - pubmed
FOCMA thus provides a useful model for antigens that might be expressed in " virus - negative " leukemias of man . - pubmed
We studied the effect of 1 - beta - ribofuranosyl-1,2,4 - traizole-3 - carboxamide ( ribavirin ) on 66 patients with acute viral hepatitis , by a double - blind study . - pubmed
The results obtained demonstrated that the ovulation - inducing effect of a single administration of estradiol benzoate ( EB ) to immature female rats is not tantamount to the induction of precocious puberty . - pubmed
Cyclophosphamide , doxorubicin and fluorouracil ( CAF ) plus depo - buserelin in the treatment of premenopausal women with metastatic breast cancer . - pubmed
A phase II study was undertaken to assess the effect of CAF plus depo - buserelin , as first - line treatment , in premenopausal women with breast cancer . - pubmed
Twenty - nine patients had metastatic disease of one site , while 31 had 2 - 4 sites . - pubmed
This study showed that CAF plus buserelin is well tolerated , with a very high response rate in selected premenopausal patients with advanced breast cancer . - pubmed
In patients with acute , subacute , or chronic sinusitis who are generally well except for persistent respiratory symptoms , of nasal discharge or cough or both , the usual bacterial isolates are Streptococcus pneumoniae , Haemophilus influenzae , an Moraxella catarrhalis . - pubmed
The effect of various types of operative interventions on the course of the early postoperative period was studied in 419 patients with duodenal ulcer . - pubmed
Two subjects who had high titres of islet - cell autoantibodies ( ICA ) without clinical diabetes produced responsive T - cell lines . - pubmed
Changes in vitreal oxygen tension distribution in the streptozotocin diabetic rat . - pubmed
Measurements of vitreal oxygen tension have been made for the first time in the streptozotocin - induced diabetic rat eye . - pubmed
A total of 36 Sprague Dawley rats were divided into a control ( n = 18 ) and streptozotocin injected group ( n = 18 ) , and after 5 - 6 weeks of established hyperglycaemia , an acute experiment was performed in which vitreal oxygen tension profiles were determined with oxygen sensitive microelectrodes . - pubmed
No significant difference was found in this mean mid vitreous value between the control rats and diabetic rats under the same systemic conditions . - pubmed
We conclude that PD or PEP when combined with FET have similar effects on short - term whole lung and regional TBC in patients with cystic fibrosis . - pubmed
[ Experiences in the control of brucellosis in cattle herds in the government district of Hannover ] . - pubmed
The tank milk screening of the dairy cattle herds to detect antibodies against Brucellosis ( and additional EBL and IBR ) has now become a standard method to continue the official status " free from ... " This is a safer and a more economic alternative to the previous blood sampling of cattle older than two years with a three years interval because this method guarantees a safe information about the serological status of each cow which is now tested at least once a year , depending on the time of dry standing status. - pubmed
The levels of both peptides were normal in patients with hyperparathyroidism and those with hypercalcemia due to various other causes . - pubmed
We prospectively studied for three years the optical correction by contact lenses of 83 aphakic infants ( 141 eyes ) who generally also had systemic and other ocular anomalies : 85 % of the patients tolerated the lens wear for the whole study period . - pubmed
Thirty - four eyes needed subsequent intraocular surgery , mostly minor , and nine patients had strabismus surgery . - pubmed
It also suggests that an excessive cadmium body burden alone may not be sufficient to induce hypertension , but in individuals whose blood pressure regulation may be impaired by other factors cadmium could stimulate the development of hypertension . - pubmed
This study also supports the recommendation to prevent hypertensive subjects from being exposed to cadmium . - pubmed
Patients with low - stage disease ( clinical stage I ) were treated successfully with modified retroperitoneal lymph node dissection ( relapse rate , three of 40 patients ) . - pubmed
Of nine patients with retroperitoneal tumors less than 3 cm in diameter , four patients were satisfactorily treated with retroperitoneal lymph node dissection alone while five patients required chemotherapy after retroperitoneal lymph node dissection . - pubmed
Of 26 patients with retroperitoneal tumors 3 to 5 cm in diameter , 17 patients were treated with chemotherapy alone . - pubmed
The concentration of serum glucose increased from 6.1 + /- 0.3 millimoles per liter ( 110 + /- 5 milligrams per deciliter ) in the control animals to 31.1 + /- 0.8 millimoles per liter ( 560 + /- 15 milligrams per deciliter ) in the untreated diabetic animals . - pubmed
After two weeks of healing , fracture callus from the untreated diabetic animals had a 29 per cent decrease in tensile strength and a 50 per cent decrease in stiffness compared with the controls . - pubmed
Splenic abscess from Fusobacterium nucleatum . - pubmed
In patients with impaired renal function , use of population estimates resulted in less accurate dosing prediction , but this less accurate performance was not observed with use of the Bayesian forecaster . - pubmed
Stroke patients . - pubmed
This study determined whether the Achilles tendon reflex , H - reflex , and ankle range of motion ( ROM ) during ambulation undergo significant changes after application of benzocaine spray applied to the triceps surae skin area of eight stroke patients displaying spasticity in ankle plantar flexor muscles . - pubmed
We therefore studied 53 PSS patients with planar ( 201Tl ) chloride myocardial scintigraphy , and 44 PSS patients with radionuclide ventriculography using red blood cells labeled in vitro with 99mTc . - pubmed
Thirty - four patients with bone tumours and tumour - like abnormalities of the skeleton , of varying ages , were examined by a computer - aided diagnostic program ; the accuracy , clinical usefulness and specific advantages and disadvantages of the program have been evaluated . - pubmed
The M / H ratios were high in leprosy patients and they exhibited a further rise in patients on treatment . - pubmed
Reconsideration of the concept of enhanced static fusimotor drive in rigidity in patients with Parkinson ' s disease . - pubmed
The electromyographic responses elicited in the first dorsal interosseus muscle by small muscle stretches or by electrical stimulation of the median nerve were investigated in parkinsonian patients and in age - matched healthy subjects . - pubmed
Scrapie - induced obesity in mice . - pubmed
Rats injected intraperitoneally with magnesium pemoline avoided a buzzing sound ( conditioned stimulus ) associated with an electric shock to the feet ( unconditioned stimulus ) more frequently than controls . - pubmed
Drug - injected rats did not avoid the foot shock more frequently than controls , although the experi mental rats did have shorter response latencies fn the active avoidance task . - pubmed
Addition of thallium acetate to infected cells ( at varying intervals of time after infection ) to control bacterial growth and conversion to the L phase during cellular disintegration decreased the number of positive L - form cultures obtained over a 10 - day period . - pubmed
Comparison of the antibiotic sensitivity of bacteria recovered from infected tissue culture cells with the stock strain of Brucella abortus indicated that some resistance to penicillin and tetracycline had developed . - pubmed
[ Monostatic localization of bone dystrophy in patients under hemodialysis for chronic renal insufficiency ] . - pubmed
Moose sickness , a neurological disease of moose infected with the common cervine parasite , Elaphostrongylus tenuis . - pubmed
Penicillin is still the antibiotic of choice for the treatment of uncomplicated gonococcal urethritis in most of the United States , but the increasing incidence of penicillinase - producing Neisseria gonorrhoeae ( PPNG ) in many areas of the world necessitates a reconsideration of standard therapy . - pubmed
Comparison of bluetongue type 20 with certain viruses of the bluetongue and Eubenangee serological groups of orbiviruses . - pubmed
Comparison of sedation , amnesia , and patient comfort produced by intravenous and rectal diazepam . - pubmed
Recovery from sedation , experience during the postoperative course , amnesia , estimation of the sedative effect , and patient preference of method of sedation were studied . - pubmed
The degree of amnesia was significantly higher during intravenous sedation , but a high degree of amnesia was not related to patients ' preference for a sedation method . - pubmed
[ Acute respiratory insufficiency in children ] . - pubmed
Food avoidance in rats : the differential effects of shock , illness and repellents . - pubmed
The numerical behaviour of the leucocytes , thrombocytes and reticulocytes of 12 patients with megaloblastic anaemia before and after additional transfusion as well as after following parenteral therapy with vitamin B12 was investigated . - pubmed
Excitation - contraction coupling in mammalian cardiac muscle during Ba2 + -induced contracture . - pubmed
The membrane potential and tension were recorded during contracture of mammalian ventricular muscles bathed in Tyrode solution with Ba2 + in the place of Ca2 + . - pubmed
Ulcerative colitis responsive to smoking and to nicotine chewing gum in a patient with alpha 1 anti - trypsin deficiency . - pubmed
For patients with smoking - responsive ulcerative colitis , non - tobacco forms of nicotine delivery such as gum or transdermal patches should be considered to avoid the hazards of cigarette smoke . - pubmed
For patients with ventricular septal defect and mitral stenosis , a series of palliative procedures and operations are often required . - pubmed
enhanced the protective action of carbamazepine , diphenylhydantoin and phenobarbital against maximal electroshock - induced convulsions in mice . - pubmed
Intracranial venous thrombosis in a patient with multiple sclerosis . - pubmed
A case is presented of a 35 - yr - old woman with multiple sclerosis who took oral contraceptives and , subsequently , experienced intracranial transverse and sigmoid sinus thromboses and , later , deep venous thrombosis of the calf . - pubmed
In addition , the diagnostic work - up and treatment options for intracranial venous thrombosis are discussed , and appropriate birth control alternatives for disabled patients , that is , diaphragm , sponges , condoms and levonorgestrel , are reviewed . - pubmed
Biopsies of colon mucous membrane obtained at colonofibroscopy of 16 adult patients with colon campylobacteriosis were studied . - pubmed
Assessment of peripheral chemoreflex contributions to exercise hyperpnea in humans . - pubmed
Most estimators of carotid chemosensitivity rely on the premise that , as the carotid bodies appear to be the sole mediators of the ventilatory response to hypoxia in humans , the entire ventilatory response to an hypoxic challenge necessarily should be ascribed to carotid chemoreceptor activation . - pubmed
PATIENTS AND METHODS : A total of 601 patients with upper ureteric calculi underwent attempted RM . - pubmed
One hundred eighty - eight patients received a common thromboembolic prophylaxis protocol with postoperative aspirin , and had a standardized surveillance protocol to detect thromboembolic complications . - pubmed
Phylogenetic analysis of feline immunodeficiency virus isolated from cats in Taiwan . - pubmed
Feline immunodeficiency virus was isolated from four cats in Taiwan . - pubmed
, the number of cross - links ) on the biodegradability behavior of these films using a strain of Pseudomonas aeruginosa was investigated . - pubmed
[ Types of hearing disorders in drug addicts and individuals drinking non - consumable alcohols ] . - pubmed
Prophylactic administration of clindamycin 2 % vaginal cream to reduce the incidence of spontaneous preterm birth in women with an increased recurrence risk : a randomised placebo - controlled double - blind trial . - pubmed
PARTICIPANTS : One hundred and sixty - eight women with a singleton pregnancy and a history of a spontaneous preterm delivery in the preceding pregnancy . - pubmed
METHODS : A total of 1,350 patients with cerebral aneurysms were operated in the Department of Neurosurgery at Santa Casa Hospital in Belo Horizonte from January 1982 to January 1998 . - pubmed
All 74 DACA aneurysms in the 72 operated patients were completely clipped , including two giant aneurysms . - pubmed
In cases of patients with multiple aneurysms who require two different craniotomies , we propose two surgical stages , starting with the aneurysm that has bled . - pubmed
In the present study , we have developed a preclinical model of allogeneic HSC transplantation into lymphoma - inoculated mice , allowing us to directly test whether purified HSCs have measurable GVT activity . - pubmed
The mechanism by which the GVT - conferring cells protect recipient mice from tumors was studied using immune defective mice as donors . - pubmed
Development of a long - term ascending urinary tract infection mouse model for antibiotic treatment studies . - pubmed
A model of ascending unobstructed urinary tract infection ( UTI ) in mice was developed to study the significance of the antibiotic concentration in urine , serum , and kidney tissue for efficacy of treatment of UTI in general and pyelonephritis in particular . - pubmed
Strain C175 - 94 achieved the highest counts in the kidneys , and this strain was subsequently used as the infecting organism . - pubmed
Use of the mouse UTI model is feasible for study of the effect of an antibiotic in the urinary system , although the missing antibacterial effect in the bladder needs further evaluation . - pubmed
RESULTS : Ten patients in the group administered Mydricaine , but no patients in the control group , developed a sinus tachycardia of & gt ; 100 beats / min for more than 10 min which was attributable to the mydriatic regime used . - pubmed
The occurrence of this response was not predictable based on the patients ' age , weight or the presence of conjunctival erythema . - pubmed
In an effort to identify patients at risk , those with significant hypersensitivity reactions were interviewed retrospectively . - pubmed
Of these , 14 patients ( 9.3 percent ) suffered significant hypersensitivity . - pubmed
Detailed history in these patients revealed possible prior " allergic sensitivity " in 78.6 percent of patients . - pubmed
In contrast , only 30 percent of 50 nonsymptomatic laser - treated patients admitted to any positive allergic tendencies . - pubmed
The latter methodology is in advanced stages of development for application in humans in the treatment of selected spinal fusions , fracture repairs , craniomaxillofacial surgery and periodontal injury and disease . - pubmed
BACKGROUND AND PURPOSE : Generalized recessive dystrophic epidermolysis bullosa ( RDEB ) is a severe inherited disease , in which patients suffer from blistering and scarring of the skin and mucous membranes after minor mechanical trauma . - pubmed
The subjects consisted of 27 cases of CBD , 30 cases of PSP , and 36 healthy controls ( CTL ) . - pubmed
In patients with refractory angina , PMR did not cause immediate deterioration in hemodynamic status or regional LV function . - pubmed
In recent years , a trend towards a decrease in male smoking has been noted , but there is still a high tobacco exposure burden in both males and females , with a forecast of a further increase in rates of lung cancer incidence and deaths . - pubmed
It also demonstrates advantages of the lumbal infusion test ( LIT ) as a part of the algorithm of the shunt operation in patients with supposed pathology of liquor malabsorption . - pubmed
The treatment of thoracic and lumbar spine fractures : a study of 123 cases treated surgically in 101 patients . - pubmed
For a total of 123 thoracolumbar traumatic lesions treated surgically in 101 patients over approximately 2 years ( all monitored clinically and radiographically up to consolidation by follow - ups after from 6 to 26 months , mean 10 months ) the technique used , complications and treatment are reported . - pubmed
Neurologic deficit was caused by fracture in 49 patients ( 40 % of the fractures or 48 % of the patients ) . - pubmed
Six patients out of 30 affected with spinal cord lesion ( 20 % ) and 15 out of 19 affected with cone and / or cauda lesion ( 79 % ) improved . - pubmed
METHODS : Rats received chemical irritation of the prostate with or without pretreatment with tamsulosin . - pubmed
[ Epidural hematoma as complication of subarachnoid anesthesia in a female patient with risk factors ] . - pubmed
Negative stress echocardiographic study predicts excellent long - term prognosis in patients with erectile dysfunction . - pubmed
However , there are no data on the role of stress echocardiography in assessing the prognosis of patients with erectile dysfunction . - pubmed
HYPOTHESIS : We sought to determine the prognostic utility of negative stress echocardiography study in subjects with erectile dysfunction and compare it to similar subjects without erectile dysfunction . - pubmed
There were 28 patients with erectile dysfunction . - pubmed
CONCLUSIONS : Our study shows that subjects with erectile dysfunction who have a negative stress echocardiographic study have a comparable event rate to similar subjects at high risk for cardiac events on long - term follow - up . - pubmed
Serological typing of Proteus strains from infantile enteritis and other sources . - pubmed
The present study reports the effects of lesions in the left amygdala on anxiety , respiration , skin conductance , heart rate , and electrical potentials in the right amygdala in two patients . - pubmed
Trait and anticipatory - state anxiety were measured before and after left amygdala resection to control medically intractable epilepsy in the patients . - pubmed
Lesions in the left amygdala resulted in decreases of trait and state anxiety , respiratory rate , and activity in the right amygdala in both patients ; one patient also showed notable decreases in skin conductance and heart rate . - pubmed
METHODS : To investigate tubular toxicity of CsA , increasing concentrations of CsA ( 1 , 2.5 , 10 , 25 , 50 and 100 micro g / ml ) and its vehicle ( cremophor ) were added to isolated rat proximal tubules ( PT ) . - pubmed
BACKGROUND : Mycobacterium avium causes disseminated infection in immunocompromised patients and triggers a process resembling Crohn ' s disease in goats . - pubmed
RESULTS : Donor ischemia time ( 188 versus 165 minutes ) and cardiopulmonary bypass time ( 127 versus 127 minutes ) were not significantly different for the retransplant patients . - pubmed
Of the 80 patients operated for multinodular lesions , malignant tumours were found in 29 and benign tumours in 36 patients ( 81 % ) and non - tumorous lesions in 15 ( 19 % ) patients . - pubmed
MATERIAL AND METHODS : This study included thirty patients following first acute myocardial infarction and thirty healthy volunteers . - pubmed
RESULTS : Except phagocytic index , all phagocytic parameters of monocytes and neutrophils were increased in acute myocardial infarction patients on admission and on the second day of hospitalization . - pubmed
On the seventh day after acute event only the mononuclear phagocyte count in fixed volume of peripheral blood showed significant increase in acute myocardial infarction patients , while percentage of phagocytosis , phagocyte count in fixed volume of peripheral blood and phagocyte capacity of neutrophils were increased during the whole investigated period . - pubmed
CsA prevents GCA in a dose - dependent fashion in the rat allograft . - pubmed
Plasma kinetics and uptake by the tumor of a cholesterol - rich microemulsion ( LDE ) associated to etoposide oleate in patients with ovarian carcinoma . - pubmed
Here , we determined in patients the plasma kinetics of LDE - etoposide oleate and verified whether the complex concentrates in ovarian carcinomas . - pubmed
METHODS : [ ( 3 ) H ]- etoposide oleate associated to LDE labeled with [ ( 14 ) C ]- cholesteryl oleate was intravenously injected into four ovarian carcinoma patients ( 50 + /- 8.7 years ) 24 h before surgery . - pubmed
Recent clinical trials have demonstrated reductions in all - cause mortality in ICD - treated patients , especially those with severe left ventricular dysfunction . - pubmed
The Use of the Rodent - adapted MEF1 Strain of Human Poliomyelitis in Neutralization Tests with Serum of Apparently Normal African Natives . - pubmed
Use of intrathecal baclofen in a child with spastic paraparesis related to human immunodeficiency virus infection : A case report . - pubmed
To my knowledge , this is the first reported successful treatment of spasticity with ITB in a patient with stable HIV infection . - pubmed
Newer non - pharmacological therapies for heart failure are being evaluated for patients of congestive heart failure ( CHF ) . - pubmed
Mechanical support with left ventricular assist devices and heart transplantation are reserved for the minority of patients who have severely decompensated heart failure . - pubmed
Despite these therapeutic advances , it is generally accepted that current therapies do not adequately address the clinical need of patients with heart failure , and additional strategies are being developed . - pubmed
It has improved exercise tolerance and NYHA functional class in such patients in sinus rhythm and a recent meta - analysis has also shown mortality benefits in CHF . - pubmed
On the apical surfaces of ciliated cells of pregnant rat respiratory epithelium disoriented cilia and cilia with dilated blebs at their free ends were observed . - pubmed
The study groups consisted of 76 preterm infants with gestational ages ranging from 28 to 36 weeks , and birthweights ranging from 1046 to 2352 g. Serum FC levels were measured in preterm infants ( group A , 37 with RDS ; group B , 39 controls without RDS ) within the first 6 hours after birth , on days 3 and 7 . - pubmed
Decreased neonatal serum carnitine levels in preterm infants with RDS during the first week of life might be caused by increasing consumption of carnitine in lung tissue for surfactant synthesis . - pubmed
The aim in the management of patients with aSAH is not only to prevent rebleedings by treating the aneurysm by either microneurosurgery or endovascular surgery , but also to evacuate acute space - occupying hematomas and to treat hydrocephalus . - pubmed
METHODS : This review is based on the experience of the authors in the management of more than 7500 patients with aSAH treated in the Department of Neurosurgery at Helsinki University Central Hospital , Finland . - pubmed
CONCLUSION : Multidisciplinary and professional teamwork is essential in the management of patients with cerebral aneurysms . - pubmed
Urinalysis before transplantation was only performed in 33 patients ( 22.8 % ) including three ( 2.1 % ) who had proteinuria . - pubmed
Device performance and construct validity are examined in in - vitro models simulating the brain , and in piglets subjected to hypoxia , hypoxia - ischemia , and hyperoxic conditions using a weighted average of arterial and cerebral venous O ( 2 ) saturation measured by CO - oximetry . - pubmed
METHODS : CBA revealed chromosomal aberrations in 18 patients suffering from myelodysplastic syndrome ( n = 13 ) , acute myeloid leukemia ( n = 3 ) , or chronic myeloproliferative syndrome ( n = 2 ) . - pubmed
This etiological agent of human trichinellosis shows worldwide distribution in domestic and/or sylvatic animals . - pubmed
Patients experienced minimal and transient side effects that included puritus , erythema and swelling . - pubmed
Mean plasma DNA concentrations were significantly increased in TBI patients ( 366,485 and 131,708 kilogenomes - equivalents / L , at study entry and 24 h later , respectively ) compared with the control group ( 3031 kilogenomes - equivalents / L ) . - pubmed
The degree of exercise hypoxemia reflects pulmonary artery pressure during early exercise in chronic obstructive pulmonary disease patients . - pubmed
To investigate whether the severity of exertional hypoxemia , as evaluated by the Deltaartery oxygen tension / Deltaoxygen consumption ( PaO(2)-slope ) correlates with the mean pulmonary artery pressure ( Ppa ) , cardiopulmonary exercise testing with haemodynamics was done in 10 patients with moderate to very severe COPD . - pubmed
Adult patients attending a pain relief unit with a diagnosis of chronic pain whose pain was described as moderate or severe were eligible for the study . - pubmed
The pathogens most frequently isolated in patients with bacteriuria were Candida albicans and Escherichia coli . - pubmed
The pathogen most frequently isolated in UTI in trauma patients was E. - pubmed
Improving soft - tissue contrast in four - dimensional computed tomography images of liver cancer patients using a deformable image registration method . - pubmed
Cushing believed that tonsillar herniation was a cause of acute cardiorespiratory compromise in patients with intracranial tumors . - pubmed
However , lupine provokes allergic reactions in susceptible individuals . - pubmed
INTRODUCTION : Strategies that optimize early diagnosis of chronic kidney disease ( CKD ) are paramount to decrease progression of the disease and the burden of patients needing renal replacement therapy . - pubmed
Although extensive studies have demonstrated the symptomatic efficacy of donepezil treatment in patients with AD , the effects of donepezil , if any , on the AD process are not known . - pubmed
In this study , we sought to determine whether long - term administration of donepezil would slow amyloid plaque deposition or confer neuronal protection in a mouse model of AD . - pubmed
These mice exhibited facial abnormalities and impaired growth , two traits associated to RSTS in humans . - pubmed
[ Comparative evaluation of the omeprasol and pantoprasol efficacy in treatment of gastropathy induced by non - steroid anti - inflammatory drugs in the patients with rheumatoid arthritis ] . - pubmed
The main criterion for the selection of suitable patients should be the cranial extent of the tumor . - pubmed
HIV as a risk factor for lung cancer in women : data from the Women 's Interagency HIV Study . - pubmed
PURPOSE : Prior reports of an increased risk of lung cancer in HIV - infected individuals have not always included control groups , nor considered other risk factors such as tobacco exposure . - pubmed
Metabolic effects of free fatty acids during endotoxaemia in a porcine model -- free fatty acid inhibition of growth hormone secretion as a potential catabolic feedback mechanism . - pubmed
The present study was designed to test whether increased levels of free fatty acids ( i ) inhibit growth hormone secretion and ( ii ) induce insulin resistance during acute endotoxin exposure in a porcine model of critical illness . - pubmed
We conclude that high levels of free fatty acids reduce circulating growth hormone concentrations in porcine endotoxaemia ; this probably constitutes a negative feedback mechanism whereby growth hormone induced - stimulation of free fatty acids release inhibit growth hormone secretion . - pubmed
Infection of man by the virus of contagious pustular dermatitis of sheep . - pubmed
Increases in carcass leanness were reported for cattle fed ZH mainly through a reduction in yield grades . - pubmed
METHODS : Genomic DNA from epithelial oral cells of 37 generalized AgP patients and 37 controls were purified and modified by sodium bisulphite . - pubmed
We present here the case of a paediatric patient with TSC in whom sirolimus has been used successfully to halt growth of renal AMLs . - pubmed
Acroangiodermatitis ( synonym pseudo - Kaposi sarcoma ) is an unusual , benign condition which clinically presents as purple - colored patches , plaques or nodules , mostly on the extensor surfaces of lower extremities in patients with chronic venous insufficiency and arteriovenous malformations . - pubmed
Eleven patients were in relapse and 8 patients were refractory to their first line of treatment . - pubmed
Infection of mice with murine gammaherpesvirus-68 ( gammaHV-68 ) serves as a model to understand the pathogenesis of persistent viral infections , including the potential for co - infections to modulate viral latency . - pubmed
We have previously found that infection of neonates ( 8 - day - old mice ) with gammaHV-68 resulted in a high level of persistence of the virus in the lungs as well as the spleen , in contrast to infection of adult mice , for which long - term latency was only readily detected in the spleen . - pubmed
BACKGROUND & amp ; AIMS : Recurrence of chronic hepatitis C and progressive fibrosis in liver transplants is frequent and impairs both graft and patient survival . - pubmed
METHODS : To induce liver fibrosis , rats underwent bile duct ligation and treatment with sirolimus ( 2mg / kg ) , everolimus ( 3mg / kg ) , tacrolimus ( 1mg / kg ) , and cyclosporin A ( 10mg / kg ) daily for 5 weeks . - pubmed
Relationship between HbA1c and coronary flow rate in patients with type 2 diabetes mellitus and angiographically normal coronary arteries . - pubmed
STUDY DESIGN : The study included 54 consecutive patients ( 36 males , 18 females ; age range 37 to 72 years ) with type 2 DM , whose coronary arteries were found normal on coronary angiography . - pubmed
Thirty - eight patients ( 70.4 % ) were found to have SCF in at least one coronary artery . - pubmed
The mean HbA1c level was significantly higher in patients with SCF compared to patients without SCF ( 7.8 + -1.9 % vs. 5.6 + -0.9 % ; p<0.001 ) . - pubmed
Hyperactivity in the amygdala and hypoactivity in the vlPFC have been reported in manic bipolar patients scanned during the performance of an affective faces task . - pubmed
Systemic complications occurred in 2 cases ( 0.7 % ) , in the form of back spasms in one patient and pulmonary edema in the other . - pubmed
A total of 31 % of patients with the preangiographic diagnosis of transverse myelitis were found to have a vascular malformation . - pubmed
South East Scotland experience of HIV testing in patients newly diagnosed with lymphoma . - pubmed
Temporal associations of early patient transfers and mortality with the implementation of a regional myocardial infarction care model . - pubmed
PURPOSE : In an effort to restore functional form vision , epiretinal prostheses that elicit percepts by directly stimulating remaining retinal circuitry were implanted in human subjects with advanced retinitis pigmentosa RP ) . - pubmed
METHODS : Experiments were performed on a single subject with severe RP ( implanted with a 16 - channel epiretinal prosthesis in 2004 ) on nine individual electrodes . - pubmed
Unlike other infections of C. - pubmed
elegans characterized to date , the infection by B. - pubmed
anthracis can result in lethal infection of C. - pubmed
Our data demonstrate that one potential property of PFPs is to sensitize the host to bacterial infection and further that C. - pubmed
Studies on Jurkat / WT human T - lymphoblastic leukemia cells showed that incorporation of paclitaxel in the nanoparticles led to a 4 - fold increase of its cytotoxicity ( 6.8x10(-6 ) M ) in comparison with paclitaxel solution . - pubmed
They are strongly associated with tobacco and alcohol consumption , but recent studies showed the presence of HPV in patients with these types of cancer . - pubmed
The incidence of cancers of the head and neck potentially attributable to HPV has increased in the last years . - pubmed
This study aims to provide population - based estimates of the burden of hospitalisation for head & amp ; neck neoplasm in Spain that may be useful when cost - effectiveness models are developed to evaluate the impact of HPV vaccination in Spain . - pubmed
Paraneoplastic neurological syndromes ( PNS ) are rare nervous system dysfunctions in cancer patients , which are not due to a local effect of the tumour or its metastases . - pubmed
PNS in adults are mainly associated with lung cancer , especially small cell lung cancer , lymphoma and gynaecological tumours . - pubmed
Since autoantibodies directed against tumour and nervous system tissue can be observed , an autoimmune aetiology has been suspected in PNS patients . - pubmed
Characterization of human herpes virus 8 genotypes in Kaposi ' s sarcoma patients in Tehran , Iran . - pubmed
Thirty rabbits underwent aortic balloon injury and were fed a high - fat diet for 20 weeks . - pubmed
This requires trials that include thousands of acute stroke patients . - pubmed
Gene array in graft - induced C3H / HeJ mice revealed that genes involved in retinoic acid ( RA ) synthesis were increased , whereas RA degradation genes were decreased in AA compared with sham controls . - pubmed
This was confirmed by immunohistochemistry in biopsies from patients with AA and both mouse and rat AA models . - pubmed
RA levels were also increased in C3H / HeJ mice with AA . - pubmed
C3H / HeJ mice were fed a purified diet containing one of the four levels of dietary vitamin A or an unpurified diet 2 weeks before grafting and disease progression followed . - pubmed
High vitamin A accelerated AA , whereas mice that were not fed vitamin A had more severe disease by the end of the study . - pubmed
Fish oil supplementation is beneficial on caloric intake , appetite and mid upper arm muscle circumference in children with leukaemia . - pubmed
A randomised trial was carried out to determine the effect of supplementation of fish oil among 51 children with leukaemia aged 4 to 12 years on appetite level , caloric intake , body weight and lean body mass . - pubmed
In conclusion , supplementation of fish oil has a positive effect on appetite level , caloric intake and MUAMC among children with leukaemia . - pubmed
Protective antibodies play a critical role in an effective HIV vaccine ; however , eliciting antibodies to block infection by viruses from diverse genetic subtypes remains a major challenge . - pubmed
Understanding the cross reactivity and specificities of serum antibody responses that mediate broad neutralization of the virus in HIV-1 infected Chinese patients will provide valuable information for the design of vaccines to prevent HIV-1 transmission in China . - pubmed
To determine the role of striatal dopaminergic innervation on upper limb synergies during walking , we measured arm kinematics in 13 subjects with Parkinson disease . - pubmed
Patients with acute appendicitis who underwent appendectomy were chosen as the control group . - pubmed
However , 73.7 % of the patients had testicular torsion when the diurnal temperature change was 6C or greater . - pubmed
Autophagy is associated with numerous patho - physiological conditions , and dysregulation of autophagy contributes to the pathogenesis of a variety of human diseases including cancer . - pubmed
A better understanding of biology of autophagy and its implication in human health and disorder , as well as the relationship between autophagy and apoptosis , has the potential of facilitating the development of autophagy - based therapeutic interventions for human diseases such as cancer . - pubmed
Patients with Alzheimer ' s disease were compared to a healthy age - matched control group . - pubmed
RESULTS : A bilateral frontal negativity in combination with deep temporal positivity occurring 500 ms after stimulus offset was reduced in patients with Alzheimer ' s disease , but was unaffected by physiological aging . - pubmed
The present study demonstrated that the TLT powers currently utilized in animal stroke studies do not cause cortical tissue heating and histopathological damage . - pubmed
Especially , lung cancer is top - ranked in cancer - associated human death . - pubmed
Taken together , these findings suggest that the novel daphnane diterpenoids might provide lead candidates for the development of therapeutic agents for human lung cancers . - pubmed
Hypoglycaemia risk among a hospitalised stroke patient cohort : a case for increased vigilance in glucose monitoring . - pubmed
We conducted a retrospective cohort study involving a review of the records of 112 patients consecutively admitted with acute stroke or transient ischaemic attack ( TIA ) to all three district general hospitals in one Health and Social Care Trust in Northern Ireland from 1 January to 15 April 2008 . - pubmed
We compared interventions and clinical outcome between patients who experienced hypoglycaemia ( glucose<4.0 mmol / l ) in the first 5 days , and patients with higher glucose results . - pubmed
Two patients experienced episodes of hypoglycaemia on 2 or more days . - pubmed
Six patients experienced hypoglycaemia at the lower threshold of glucose<3.5 mmol / l and this was not associated with a history of diabetes . - pubmed
A history of diabetes mellitus prompted near patient glucose testing , but among patients without diagnosed diabetes , glycaemia was under - monitored . - pubmed
Patients in the first 5 days after stroke have a small risk of hypoglycaemia . - pubmed
There is a need for greater vigilance in the monitoring of glucose among patients admitted to hospital with stroke or TIA . - pubmed
METHODS : PPMOs were evaluated in vitro using minimum inhibitory concentration ( MIC ) and viability assays , and in vivo using murine pulmonary infection models with intranasal PPMO treatment . - pubmed
Mice treated with & gt;=0.25 mg / kg of ( RXR)4 - AcpP survived longer and had less inflammation and bacterial lung burden than mice treated with a scrambled - sequence PPMO or phosphate - buffered saline . - pubmed
[ Clinically mild encephalitis / encephalopathy with a reversible splenial lesion of corpus callosum in a child and literature review ] . - pubmed
METHOD : The clinical and imaging features of one pediatric patient with the diagnosis of MERS were analyzed and the clinical and radiologic data of 44 MERS cases which were reported all around the world were also analyzed . - pubmed
On the second day of the disease course , the patient presented symptoms of encephalopathy . - pubmed
Most of the 44 patients diagnosed with MERS were associated with infectious diseases and completely recovered within two weeks . - pubmed
Donor cell - derived myelodysplastic syndrome with ring chromosome 7 after allogeneic hematopoietic stem cell transplant in 2 patients with lymphomas as primary disease . - pubmed
INTRODUCTION : T - condylar fractures of the humerus are very rare in children . - pubmed
METHODS : The study encompassed total of 19 patients with T - condylar fracture , aged from 3 to 16 years , who underwent either closed or opened reduction between February 2005 and September 2012 . - pubmed
According to the type of fracture , excellent results were achieved in 10 , good in 8 and poor in one patient . - pubmed
RESULTS : Eighty ( 57 % ) patients were identified as having THAA . - pubmed
There were three surgical reinterventions ( PAA in 2 patients and distal aortic arch in 1 patient ) and nine catheter reinterventions ( all related to anastomotic stenosis ) during a median follow - up period of 18 months . - pubmed
CONCLUSIONS : The hypoplastic PAA segment in patients with CoA / THAA grew significantly after EEEA but remained smaller than in those without THAA . - pubmed
Contrast Free Duplex - Assisted EVAR in Patients with Chronic Renal Insufficiency . - pubmed
This report describes three cases of duplex - assisted EVAR in patients with chronic renal insufficiency . - pubmed
Anti - Saccharomyces cerevisiae antibody titres correlate well with disease activity in children with Crohn ' s disease . - pubmed
Of 28 children with RSE , eleven ( 39 % ) were treated with a pentobarbital infusion after failure to control RSE with a benzodiazepine infusion ; while17 children ( 61 % ) required only a benzodiazepine infusion . - pubmed
Children requiring pentobarbital therapy were more likely to develop hypotension , require inotropic support , need intubation , mechanical ventilation , peripheral nutrition , and blood products ; furthermore , they were more likely to develop hypertension and movement disorder after or during weaning . - pubmed
In conclusion , children with RSE who required pentobarbital therapy had a longer hospital stay with more complications . - pubmed
Respiratory syncytial virus ( RSV ) is a leading cause of lower respiratory tract infections in children . - pubmed
CONCLUSIONS : Despite the effectiveness of the treatment with topical 3 % diclofenac in 2.5 % HA , the patients who achieve the complete clinical response should be adequately educated to continue their photoprotection in order to minimize recurrence of AK . - pubmed
Robust effects of genetic background on responses to subarachnoid hemorrhage in mice . - pubmed
Outcome varies among patients with subarachnoid hemorrhage but known prognostic factors explain only a small portion of the variation in outcome . - pubmed
We hypothesized that individual genetic variations influence brain and vascular responses to subarachnoid hemorrhage and investigated this using inbred strains of mice . - pubmed
Subarachnoid hemorrhage was induced in seven inbred and a chromosome 7 substitution strain of mouse . - pubmed
After 48 h of subarachnoid hemorrhage , mice showed significant middle cerebral artery vasospasm that correlated positively with reduction in cerebral blood flow at 45 min . - pubmed
Mice also had increased neuronal injury compared to sham controls ; A / J and C57BL/6 J strains represented the most and least severe , respectively . - pubmed
Our data suggested that mouse genetic background influences outcome of subarachnoid hemorrhage . - pubmed
These findings also have implications for animal modeling of disease and suggest that genetic differences may also modulate outcome in other cardiovascular diseases . - pubmed
METHODS : Fifty - eight patients affected with RA , AS and PsA were prospectively enrolled . - pubmed
Currently , pemetrexed ( PMX)-based chemotherapy is the mainstay of chemotherapy for MPM , however , the outcome of PMX - based chemotherapy in patients with MPM is dismal . - pubmed
METHODS : This cross - sectional study investigated 68 children and adolescents with IBD ( 57 Crohn disease , 11 ulcerative colitis ) . - pubmed
Hypothalamic paraventricular nucleus stimulation reduces intestinal injury in rats with ulcerative colitis . - pubmed
CONCLUSION : Chemical stimulation of the hypothalamic PVN provides a protective effect against UC injury in rats . - pubmed
The versatility and functionality of this system was successfully validated in several lactobacilli species ; furthermore , we assessed in vivo LIVE system in two different mouse models of human pathologies : ( i ) a model of therapy against intestinal inflammation ( inflammatory bowel diseases ) and ( ii ) a model of vaccination against dental caries . - pubmed
In addition , the significant antibacterial efficacy and antibiofilm activity of biopolymer capped AgNPs were demonstrated against different bacterial strains , Staphylococcus aureus MTCC 740 and Escherichia coli MTCC 9492 . - pubmed
Although adjuvant chemoradiotherapy has been an important part in the treatment of gastric cancer , whether or not adjuvant radiation can benefit patients undergoing resection with D2 lymph node dissection remains controversial . - pubmed
A total of 337 patients with resected gastric cancer treated at Zhongnan Hospital of Wuhan University from 2004 to 2012 were retrospectively analyzed . - pubmed
Patients completed the neck disability index ( NDI ) , short - form 12 ( SF-12 ) and visual analog pain scale ( VAS ) before surgery , then at 3 , 6 , 12 , and 24 months after surgery . - pubmed
The acute hemodynamic response to captopril ( 8 patients ) and enalapril ( 8 patients ) was evaluated in congestive heart failure patients in NYHA functional class III . - pubmed
All patients had a history of congestive heart failure for more than six months . - pubmed
One patient in the captopril group deteriorated and underwent a successful heart transplantation and one patient in the enalapril group returned with arrhytmias and hypertension ( probably not drug - related ) after 48 h of therapy . - pubmed
CONCLUSION : Dermoid tumors should be considered among the differential diagnosis of intradural lesions in young patients even without any other congenital abnormality . - pubmed
This multicenter , double - blind , randomized , parallel - group , non - inferiority study compared the efficacy and safety of morinidazole with those of ornidazole in women with pelvic inflammatory disease . - pubmed
For women with pelvic inflammatory disease , twice - daily morinidazole for 14 days was clinically and bacteriologically as efficacious as twice - daily ornidazole for 14 days , while the former was associated with fewer drug - related adverse events than the latter . - pubmed
Vitamin D levels are commonly lower in patients with GH deficiency ( GHD ) than in controls , with a variable prevalence of insufficiency or deficiency , and this condition may worsen the already known cardiovascular and metabolic risk of GHD , although this finding is not common to all studies . - pubmed
We enrolled 110 patients with advanced NPC . - pubmed
A 39 year - old woman with malignant foot melanoma underwent wide excision of the primary tumor with a safety margin and sentinel lymph node biopsy ( SLNB ) for the right inguinal lymph node . - pubmed
Patients with increased craniofacial injuries have an increased risk for airway complications and need for tracheostomy . - pubmed
Short- and long - term outcomes of laparoscopic radical hysterectomy for obese patients with cervical cancer . - pubmed
PURPOSE : To perform a preliminary comparison of the short- and long - term outcomes of laparoscopic hysterectomy ( LH ) between obese and non - obese patients with cervical cancer . - pubmed
METHODS : A total of 243 cases of cervical cancer patients were treated with LH between April 2009 and January 2016 . - pubmed
Based on their body mass index ( BMI ) at the time of surgery , patients were divided into an obese group ( BMI & gt;= 25 kg / m2 ) and a non - obese group ( BMI & lt ; 25 kg / m2 ) . - pubmed
RESULTS : Sixty - four patients were classified as obese and 179 as non - obese . - pubmed
The proportion of patients with type-2 diabetes mellitus ( p=0.006 ) , hypertension ( p=0.021 ) , and hyperlipidemia ( p=0.008 ) in the obese group was significantly higher than that in the non - obese group . - pubmed
Compared with the non - obese group , the obese patients had longer operative time ( p=0.039 ) , more intraoperative blood loss ( p=0.025 ) , and a higher rate of conversion ( p=0.025 ) . - pubmed
METHODS : Three patients with giant condylar osteoma were enrolled in this study . - pubmed
Pain relief of the joint and mouth - opening improvement were significant in 3 patients . - pubmed
Cryptococcus neoformans is a common environmental yeast and opportunistic pathogen responsible for 15 % of AIDS - related deaths worldwide . - pubmed
Dose - dependent acute phase response of aqueous leaf decoction of Nerium oleander in Wistar rats . - pubmed
Identification of prognostic factors for activities of daily living in elderly patients after hospitalization for acute infectious disease in Japan : A 6 - month follow - up study . - pubmed
METHODS : The present prospective cohort study included 131 patients who were hospitalized due to acute infectious disease and who had undergone rehabilitation during hospitalization . - pubmed
Temporal Stability of Rotors and Atrial Activation Patterns in Persistent Human Atrial Fibrillation : A High - Density Epicardial Mapping Study of Prolonged Recordings . - pubmed
BACKGROUND : The prevalence , stability , and mechanistic importance of rotors in human atrial fibrillation ( AF ) remain unclear . - pubmed
CONCLUSIONS : In patients with longstanding , persistent AF , activation patterns are spatiotemporally stable over 10 min . - pubmed
We aimed to evaluate all types of patients with FH using the potentially more sensitive speckle tracking echocardiography ( STE ) technique to identify early left ventricular ( LV ) dysfunction . - pubmed
Nine homozygote , two compound heterozygote , and 82 heterozygote FH patients and 85 healthy subjects were prospectively studied . - pubmed
Our study found that cardiac functions of homozygote patients who had the highest cholesterol levels were disrupted at very early ages . - pubmed
Correction to : Effect of a short - term dietary supplementation with phytosterols , red yeast rice or both on lipid pattern in moderately hypercholesterolemic subjects : a three - arm , double - blind , randomized clinical trial . - pubmed
Safety and efficacy of Nab - paclitaxel plus gemcitabine in patients with advanced pancreatic cancer suffering from cholestatic hyperbilirubinaemia - A retrospective analysis . - pubmed
INTRODUCTION : Treatment of patients with advanced pancreatic carcinoma ( APC ) and hyperbilirubinaemia is problematic because these patients were regularly excluded from clinical studies . - pubmed
This retrospective study investigated the safety and efficacy of nab - P / G in patients with APC and cholestatic hyperbilirubinaemia . - pubmed
METHODS : We screened our prospective database for patients with APC treated with nab - P / G at total bilirubin levels of & gt;=1.2 mg / dl . - pubmed
Patients were risk stratified according to the CMML - specific Prognostic Scoring System ( CPSS ) and the MD Anderson Prognostic Scoring System . - pubmed
MP - CMML patients had significantly shorter overall survival ( OS ; P & lt ; .0001 ; hazard ratio : 0.53 , 95 % confidence interval : 0.42 - 0.65 ) and median duration to acute myeloid leukemia ( AML ) transformation ( P & lt ; .0001 ; 15.2 vs 22.0 months ) compared with MDS - CMML patients . - pubmed
Forty - three percent of patients developed radiation retinopathy , and 20 % developed optic neuropathy ; 39 % lost & gt;=6 Snellen lines of vision . - pubmed
BACKGROUND : The topic of whether preoperative Th1 / Th2 cells and their related factors have a predictive value for postoperative febrile urinary tract infection ( UTI ) in patients with ureteral calculi has not been explored . - pubmed
MATERIAL AND METHODS : One hundred sixty patients who underwent ureteroscopic pneumatic lithotripsy in the Affiliated Hospital of Hangzhou Normal University ( China ) were recruited and divided into febrile UTI group ( n = 78 ) and non - UTI group ( n = 82 ) . - pubmed
CONCLUSIONS : Perioperative Th2 dominance was correlated with the risk of postoperative febrile UTI after ureterscopy in patients with ureteral calculi , which can provide clinical guidance for the development of individualized treatment . - pubmed
CONCLUSION : Once - weekly semaglutide was considered highly cost - effective versus liraglutide 1.2 mg for the treatment of patients with type 2 diabetes in Estonia . - pubmed
In the second patient suffering from hepatic cirrhosis and hospitalized because of esophagogastric bleeding the deforming posterior ventricle wall lump was discovered during the laparotomy and stomach operating exploration . - pubmed
Impact of immunohistochemistry on the diagnosis and management of primary aldosteronism : An important tool for improved patient follow - up . - pubmed
Most patients with aldosterone - producing adenoma are biochemically cured by unilateral adrenalectomy , but patients with bilateral hyperplasia have a significant risk of residual or recurrent disease . - pubmed
MATERIALS AND METHODS : : A total of 39 patients with primary aldosteronism who underwent unilateral adrenalectomy for a presumed adenoma during 2013 - 2016 were included . - pubmed
RESULTS : : In all , 22 patients had an aldosterone - producing adenoma , while 13 patients were judged to have hyperplasia . - pubmed
This procedure should be part of the histopathological routine in all operated primary aldosteronism patients . - pubmed
During an annual corn disease survey in mid - September 2001 , sporadic symptoms typical of gray leaf spot ( causal agent Cercospora zeae - maydis Tehon & amp ; E.Y. - pubmed
We have suspected that gray leaf spot has been present in Ontario for a few years based on unconfirmed reports from the seed corn industry , but to our knowledge , this is the first confirmed report of this pathogen in Canada . - pubmed
After 1 , 3 , and 6 months operation , the animals were sacrificed , and the repair outcomes of chondral defects were evaluated using Magnetic Resonance Imaging ( MRI ) , macro- and microscopic observation , and histological analysis . - pubmed
Thus , we provide a robust method to reproducibly generate 3D human midbrain organoids containing mDANs to investigate PD - relevant patho - mechanisms . - pubmed
AIMS : Patients undergoing coronary artery bypass grafting ( CABG ) surgery may experience neurological impairment . - pubmed
Impact of contrast ultrasound diagnosis for patients with liver cancer . - pubmed
Introduction : Soft - robotic gloves have been developed to enhance grip to support stroke patients during daily life tasks . - pubmed
Conclusions : Based on these promising results , further research will be done to investigate the possibility to use classification of the movements in stroke patients . - pubmed
In this study , we evaluated 118 patients with Parkinson ' s disease matched for age , sex and education with 35 healthy control subjects . - pubmed
Patients with Parkinson ' s disease were classified with normal cognition ( n = 52 ) , mild cognitive impairment ( n = 46 ) , and dementia ( n = 20 ) based on an extensive neuropsychological evaluation . - pubmed
Four out of 23 ( 17 % ) patients developed Grade 3 skin toxicity . - pubmed
Conclusions : For patients not eligible for surgery , radiation therapy is an option with a moderate chance of complete response ( 65 % ) and a 17 % risk of poor wound healing / radiation necrosis . - pubmed
In this study , we recruited 26 long - term institutionalized schizophrenia patients , 27 community - dwelling schizophrenia patients , and 27 healthy controls . - pubmed
In this study , we utilized a human neural stem cell ( hNSC)-based system to evaluate the potential developmental neurotoxic effects of the above - mentioned five chemicals , at environment and human exposure relevant concentrations . - pubmed
We previously reported that dietary Glu - Cer from rice bran had inhibitory effects on human head and neck squamous cell carcinoma ( HNSCC ) in nonobese diabetes ( NOD )/ severe combined immunodeficiency ( SCID ) mice . - pubmed
The purpose of the present study was to determine whether dietary Glu - Cer had anticarcinogenic and antitumorigenic effects in a mouse model of HNSCC . - pubmed
RESULTS : Compared with the Glu - Cer group mice , control group mice more frequently developed individual and multiple tumors of each type , including CIS and SCC , in the mouth , pharynx , or esophagus . - pubmed
CONCLUSION : Tumor development was effectively inhibited by dietary Glu - Cer derived from rice bran , indicating that this and related compounds show promise as prophylactic agents for human HNSCC . - pubmed
Nematode - Associated Bacteria : Production of Antimicrobial Agent as a Presumptive Nominee for Curing Endodontic Infections Caused by Enterococcus faecalis . - pubmed
Deep partial - thickness burn wounds were created on the back of Bama pigs . - pubmed
Minimally invasive surgery in elderly patients with rectal cancer : An analysis of the Bi - National Colorectal Cancer Audit ( BCCA ) . - pubmed
Elderly patients had more postoperative complications ( p < 0.0001 ) and had a longer length of hospital stay ( LOS ; median 11 vs. 8 days for both other groups ; p < 0.0001 ) . - pubmed
CONCLUSIONS : MIS is performed in just over half of elderly rectal cancer patients who are selected for elective rectal resection surgery in ANZ . - pubmed
We developed a multi - functional nanocomposite hydrogel that exhibited antibacterial and angiogenic properties , adhesiveness , and mechanical properties that enhance the regeneration of bacteria - infected wounds . - pubmed
Angiokeratomas and treatment with enzyme replacement therapy in a patient with Fabry disease . - pubmed
Although it is well established that enzyme replacement therapy ( ERT ) prevents or slows the progression of disease on target organs in the majority of patients , the long - term effect of ERT on angiokeratomas remains unknown . - pubmed
We present a patient diagnosed with Fabry disease at age 11 , with rapid progression of new angiokeratomas in typical regions before beginning treatment with ERT . - pubmed
Basaloid squamous cell carcinoma is commonly observed in the oropharyngeal and anogenital regions and is associated with high - risk human papillomavirus . - pubmed
Histopathologic investigations of high - risk cutaneous squamous cell carcinoma do not routinely involve human papillomavirus testing . - pubmed
Since the patient presented with an aggressive variant of squamous cell carcinoma and distal metastasis despite standard therapies , human papillomavirus testing was performed . - pubmed
This is a unique report of HPV16 in primary cutaneous basaloid squamous cell carcinoma with distal brain metastasis . - pubmed
Black soybean has many beneficial physiological activities , and its prevention effects on CVD risk were reported mainly in animal experiments . - pubmed
Transcatheter aortic valve replacement ( TAVR ) offers a safe and effective therapy for high - risk patients suffering from aortic valve stenosis . - pubmed
We present a case of a 15 - year - old patient , diagnosed 4 years before with severe idiopathic pulmonary hypertension , confirmed by catheterism , with continuous follow up . - pubmed
METHODS : The patients with acute lower limb ischemia who underwent percutaneous mechanical thrombectomy between August 2016 and February 2018 were retrospectively reviewed . - pubmed
Recanalization of the thromboembolic occlusions were achieved in all patients . - pubmed
Complete thrombus removal was achieved in all patients . - pubmed
White - nose syndrome ( WNS ) is an emerging disease of hibernating bats caused by an environmentally persistent fungus , Pseudogymnoascus destructans . - pubmed
Orbital Swelling in a Child With Retinoblastoma Following Intra - arterial Chemotherapy . - pubmed
This study was conducted to evaluate the effect of high - dose VitD administration in patients with VitD insufficiency on the incidence of postoperative AKI , the urinary level of tubular biomarkers , and serum anti - inflammatory biomarker after coronary artery bypass graft . - pubmed
The patients with AKI had more postoperative bleeding and received more blood transfusion . - pubmed
This study was designed to investigate the sensitivity of SARS - CoV-2 to different temperatures , to provide basic data and a scientific basis for the control of COVID-19 epidemic . - pubmed
METHODS : We included papers comparing melatonin levels between healthy controls and human patients belonging to the AD continuum . - pubmed
Literature was not conclusive regarding alterations in blood daytime melatonin levels or regarding saliva melatonin in AD patients . - pubmed
Decreased total and night - time melatonin production has been described in urine of AD patients . - pubmed
The most common clinical finding in five patients who died after deliberately taking overdoses of disopyramide was an early loss of consciousness after an apnoeic episode . - pubmed
An initial response to resuscitation and antiarrhythmic drugs in four patients was not sustained and these patients deteriorated rapidly with cardiac arrhythmias and loss of spontaneous respiration . - pubmed
Sera from convalescent cholera patients possessed toxin - neutralizing antibody as well as passive hemagglutination and radioimmunoassay antibody against both A and B subunits . - pubmed
[ Haemolysis of white rat erythrocytes by pathogenic and saprophytic strains of leptospires ( author 's transl ) ] . - pubmed
Effects of low and high frequency noise bands in producing a physiologic correlate of loudness recruitment in mice . - pubmed
The effects of hyperketonemia on glutamate and glutamine metabolism in developing rat brain . - pubmed
The immunofluorescent staining properties of 65 serum samples from 54 patients with multiple sclerosis ( MS ) , 63 samples from 55 patients with other neurological diseases ( OND ) , and sera from 14 healthy normal individuals were examined on frozen sections of bovine and human brain . - pubmed
When tested on bovine brain sections , positive oligodendrocyte staining was present in 63 % of MS sera , 43 % of OND sera , and 29 % of normal sera . - pubmed
[ Intravenous leucine load in patients with cirrhosis of the liver ( author 's transl ) ] . - pubmed
In 6 patients with cirrhosis of the liver and in 6 healthy controls the elimination half life of the serum leucine level ( t 1/2 Leu ) was determined after intravenous administration of 50 mg leucine per kg bodyweight . - pubmed
It is concluded for human erythrocytes that 1 ) the increased permeability of the membrane to calcium produced by hypertonicity is a time - dependent , reversible phenomenon and is independent of calcium , 2 ) the increase in intracellular potassium concentration associated with hypertonic exposure is an important factor contributing to this response , and 3 ) interactions between calcium and components of the sodium - potassium transport system may account for the enhanced uptake of calcium produced by hypertonicity . - pubmed
Failure to produce warts on human skin grafts on ' nude ' mice . - pubmed
Comparative activity of various compounds against clinical strains of herpes simplex virus . - pubmed
Disturbances of neurovascular function in the extremities may occur in patients with diabetes mellitus , exposure to toxic substances and chronic exposure to vibrating hand tools , as well as in Raynaud ' s phenomena . - pubmed
All subjects were consenting volunteers without exposure to known neurotoxic chemicals . - pubmed
There was a significant reduction ( P & lt ; 0.05 ) in the neurovascular responses of both diabetics and vibration -- exposed subjects to acetylcholine and , in the case of vibration - exposed subjects , to pilocarpine , but nitroprusside responses were not significantly different . - pubmed
Our findings of reductions in neurovascular responses in diabetics and in subjects exposed to higher frequency vibration is consistent with recent epidemiological findings . - pubmed
Human African trypanosomiasis : presence of antibodies to galactocerebrosides . - pubmed
Steady - state pharmacokinetics of hydroxychloroquine in rheumatoid arthritis patients . - pubmed
Steady - state pharmacokinetics of hydroxychloroquine ( HC ) sulfate ( Plaquenil ) were studied in five volunteers with rheumatoid arthritis who had taken 6 mg / kg / d of the drug for at least six months . - pubmed
30 patients with a hypertensive intracerebral hematoma were treated by stereotactic evacuation between 1986 and 1988 . - pubmed
In 19 patients the hematoma was found in the internal capsule , in 5 in the cerebellum , in 4 in the subcortex , and in 2 in the brain stem . - pubmed
More than 80 % of the hematoma could be aspirated in 20 patients and 60 - 80 % in 10 . - pubmed
One hundred and twenty - three specimens ( 83 primary and 40 metastatic ) of colorectal cancers from 102 patients were subjected to the human tumor clonogenic assay ( HTCA ) to determine the clonogenicities of tumor specimens stratified by the degree of histological differentiation and of tumor progression . - pubmed
Infection due to Pseudomonas aeruginosa persisted or recurred in three patients with chronic osteomyelitis ; in two of them , the strain become resistant to ciprofloxacin , and in the third patient , the results of cultures persisted positive along the whole course , thus , the eradication of the microorganism was not achieved . - pubmed
Declining platelet counts and platelet aggregation during porcine VIII : C infusions . - pubmed
In this study Aspergillus species ( niger and fumigatus ) have been the most common fungal pathogens . - pubmed
In order to help clarify the clinical importance of chronic erosive gastritis , we describe our experience of 28 patients with this disorder who were seen over a 2 - yr period . - pubmed
Three patients presented with painless vomiting . - pubmed
Symptoms in patients with chronic erosive gastritis appear to be due to the gastritis itself rather than to associated lesions . - pubmed
The risk of cancer to humans exposed to soil treated with wastewater / sewage treatment plant sludge , known to be contaminated with small amounts of polychlorinated dibenzodioxins and dibenzofurans ( PCDDs and PCDFs ) , was evaluated . - pubmed
Blood pressure response to oral calcium in persons with mild to moderate hypertension . - pubmed
The blood pressure response of 48 hypertensive persons and 32 normotensive persons to elemental calcium ( as the carbonate or citrate salt ) , 1000 mg / d for 8 weeks , was assessed in a randomized , double - blind , placebo - controlled , crossover trial . - pubmed
Compared with placebo , Ca2 + significantly lowered supine systolic blood pressure by 3.8 mm Hg , standing systolic blood pressure by 5.6 mm Hg ( p less than 0.02 ) , and supine diastolic blood pressure by 2.3 mm Hg ( p less than 0.05 ) in hypertensive persons . - pubmed
The response in normotensive persons differed significantly from that in hypertensives ( p less than 0.03 ) as their blood pressure was unchanged . - pubmed
Twenty - one ( 44 % ) hypertensive and 6 ( 19 % ) normotensive persons achieved a reduction in standing systolic arterial pressure of 10 mm Hg or greater . - pubmed
Treatment with 1000 mg / d of oral Ca2 + for 8 weeks represents a safe , well - tolerated , nonpharmacologic intervention that lowers blood pressure in selected patients with mild to moderate hypertension . - pubmed
Twenty patients sustaining out - of - hospital cardiopulmonary arrests and basic cardiac life support were instrumented with thoracic aortic and right atrial catheters on arrival in the emergency department . - pubmed
Three patients had systolic Ao - RA gradients of more than 25 mm Hg , which is consistent with some cardiac compression as a mechanism of flow . - pubmed
In 11 adult patients with isolated valvular aortic stenosis , the progression of the disease was assessed by two heart catheterisations without intervening aortic valve surgery . - pubmed
Four patients had bicuspid valves , whereas the remaining seven were considered to have acquired aortic stenosis . - pubmed
[ Comparison of the clinical course and secretory activity of the stomach in smoking and non - smoking patients with peptic ulcer ] . - pubmed
Influence of toyocamycin on avian leukemia myeloblasts : cell growth , ultrastructure , RNA synthesis , and elaboration of BAI strain A virus . - pubmed
Cigarette smoking and cholesterol atherosclerosis of rabbits . - pubmed
Observations on the histogenesis of the inner ear degeneration of the deaf white cat and its possible relationship to the aetiology of certain unexplained varieties of human congenital deafness . - pubmed
A number of arboviruses have been associated with congenital defects in domestic aminals and man . - pubmed
In dog saphenous vein bileaflet valves , there was a large primary spiral vortex as well as a smaller secondary vortex , the latter acting as a trap and generator of thrombi . - pubmed
Transfer of delayed hypersensitivity induced by Schistosoma japonicum adult worm antigen in guinea pigs . - pubmed
Increased systemic vascular responsiveness to catecholamines in spontaneously hypertensive rats . - pubmed
bolus injections of norepinephrine and tyramine was evaluated in adult male spontaneously hypertensive rats ( SHR ) and normotensive Wistar - Kyoto rats ( WKY ) . - pubmed
Left ventricular function in patients with chronic obstructive pulmonary disease . - pubmed
We assessed the left ventricle function in 24 patients with severe ( forced expiratory volume in 1 sec less than 50 % of predicted ) chronic obstructive pulmonary disease ( COPD ) and in 21 normal people . - pubmed
In 13 of the 24 patients with COPD the mean pulmonary artery pressure and pulmonary artery wedge pressure were recorded . - pubmed
The STI in the patients with COPD were found abnormal while the echocardiographic parameters and pulmonary wedge pressure were normal . - pubmed
The effect of quiet conversation on the blood pressure of hypertensive patients . - pubmed
Seventy - five women with aortoiliac ( A - I ) occlusive disease requiring vascular reconstruction during the past 4 years were reviewed . - pubmed
Women presented with elevated triglyceride levels as opposed to increased cholesterol , with frequent type IV hyperlipoproteinemia . - pubmed
[ Russian preparations for the metabolic therapy of multiple sclerosis patients ] . - pubmed
The patient with type II , or non - insulin - dependent , diabetes mellitus ( NIDDM ) is characterized by obesity and insulin resistance , with resultant hyperinsulinemia and hyperglycemia . - pubmed
With sulfonylureas and metformin , therapy for the patient with NIDDM can be more effectively tailored . - pubmed
Valproate in the treatment of behavioral agitation in elderly patients with dementia . - pubmed
Ten nursing home patients ages 71 to 94 years with dementia and behavioral agitation were treated prospectively with open - label valproate at doses of 375 to 750 mg / day over periods of time ranging from 4 to 34 weeks . - pubmed
Eight ( 80 % ) of the 10 patients showed a 50 % or greater reduction in the frequency of episodes of behavioral agitation . - pubmed
The authors conclude that valproate may be an effective , well tolerated , and safe treatment for behavioral agitation in elderly patients with dementia . - pubmed
Combination chemotherapy appears to extend the time window for acute stroke therapy in rats to 1 h and to result in fewer side effects . - pubmed
Liver transplantation in patients with preexisting malignancy . - pubmed
In 1991 , a total of 1,829 MTAs were recorded in Muhimbili Medical Centre and these claimed 113 human lives on the spot and impaired 2,834 who had to attend medical services for injuries . - pubmed
Subjective patient satisfaction recorded 47 ( 94 % ) good to excellent results , with an average pain relief grade of 87 % . - pubmed
Between January 1962 and December 1991 , 179 children less than 1 year of age underwent repair of coarctation of the aorta . - pubmed
[ Generalized idiopathic epilepsy in older children and adolescents ] . - pubmed
A patient presented with a history of chronic corneal ulceration and corneal hypoaesthesia . - pubmed
We treated 70 patients with acute promyelocytic leukemia ( APL ) with daily oral 45 mg / m2 all - trans retinoic acid ( ATRA ) in 2 multi - institutional prospective studies . - pubmed
Of 63 evaluable patients , 21 were resistant to initial induction chemotherapy , 10 were resistant to salvage chemotherapy after relapse , 17 were in the first relapse , 4 in the second relapse , 4 in the third relapse , and 7 were previously untreated . - pubmed
This review identified 300 patients who experienced in - hospital cardiopulmonary arrest during the study period . - pubmed
[ Anterior chamber dimensions in patients with angle - closure glaucoma measured by an anterior eye segment analysis system ] . - pubmed
The corneal curvatures , iridocorneal angles , anterior chamber depths , and anterior chamber volumes in 26 ( 5 male and 21 female ) patients with primary angle - closure glaucoma were measured using an anterior eye segment analysis system ( EAS-1000 , Nidek ) . - pubmed
These findings may help elaborate neuronal models of feeding control and perhaps facilitate progress in the pharmacotherapy of human obesity and eating disorders . - pubmed
The drug is embryotoxic in rodents and has been reported to produce neural tube defects in approximated 1 % of prenatally exposed human offspring . - pubmed
The present study was designed to determine the embryotoxicity of CBZ and its epoxide intermediate ( CBZ - E ) in a rodent whole embryo culture system . - pubmed
The parent compound was embryotoxic to mouse embryos at concentrations as low as 12 micrograms , but it was only embryotoxic at 60 micrograms / ml to rat embryos . - pubmed
A double - blind comparison of fluvoxamine and paroxetine in the treatment of depressed outpatients . - pubmed
BACKGROUND : Fluvoxamine and paroxetine , both serotonin selective reuptake inhibitors ( SSRIs ) , were compared at two centers in a 7 - week double - blind study in outpatients with major depression , diagnosed by DSM - III - R criteria . - pubmed
The most common events were headache ( N = 17 , 57 % ) , nausea ( N = 14 , 47 % ) , sweating ( N = 10 , 33 % ) , somnolence ( N = 9 , 30 % ) , diarrhea ( N = 9 , 30 % ) , dry mouth ( N = 8 , 27 % ) , dizziness ( N = 8 , 27 % ) , and , among males , impotence ( N = 3 , 21 % ) and ejaculatory abnormality ( N = 3 , 21 % ) in the paroxetine group , and headache ( N = 12 , 40 % ) , somnolence ( N = 12 , 40 % ) , nausea ( N = 11 , 37 % ) , dry mouth ( N = 11 , 37 % ) , insomnia ( N = 9 , 30 % ) , asthenia ( N = 7 , 23 % ) , and dyspepsia ( N = 7 , 23 % ) in the fluvoxamine group . - pubmed
However , there were no independent specific risk significant factors for viridans streptococcal bacteraemia and bacteraemia due to Enterobacteriaceae or Ps . - pubmed
We also did not observe any association between prior therapy with imipenem and Stenotrophomonas maltophilia bacteraemias . - pubmed
However , the mortality of fungaemia was statistically no different from that of Ps . - pubmed
HIV and pneumococcal infection in Africa . - pubmed
By the 1930s several studies had shown that Streptococcus pneumoniae was an important pathogen in Nairobi ( Kenya ) and various risk factors for infection were recognized , including seasonally cold conditions , overcrowding and recent arrival in the city . - pubmed
One study showed HIV seropositivity to confer a relative risk of 17.8 for pneumococcal infection . - pubmed
HIV - seropositive patients were more prone to infection with penicillin- and tetracycline - resistant organisms than seronegative patients ( penicillin , 27 % vs. 7 % ; tetracycline , 40 % vs. 17 % ) , a difference reflected by different serotype profiles in the 2 groups . - pubmed
[ Effect of osthol and total coumarins of fructus cnidii on thyroid hormone and thyrotropic hormone in kidney - yang deficiency rats ] . - pubmed
It was suggested that the osthol and total coumarins of Fructus Cnidii could elevate the pituitary - thyroid axis function of Kidney - Yang Deficiency rats . - pubmed
One patient with VATS debridement subsequently required thoracotomy and lobectomy for lung abscess . - pubmed
Assessment of the patients ' mood , general behavior , cognitive functions ( MMSE ) , orientation and confusion ( OBS ) was made at baseline , and after 6 and 12 months of intervention . - pubmed
Significant deteriorations for the patients in CW were seen during the study period as regards the factor strength , functional performance and orientation in the ward , and speech performance and psychomotor slowing . - pubmed
Application of nucleus pulposus to the nerve root simultaneously reduces blood flow in dorsal root ganglion and corresponding hindpaw in the rat . - pubmed
Edema was the principal pathologic finding seen consistently in the nerve roots and in many of the associated dorsal root ganglia from nucleus pulposus - treated animals . - pubmed
Administration of the PG synthesis inhibitor , indomethacin , to wild - type mice during the fibrogenic phase postbleomycin worsened the severity of fibrosis , implying a causal role for PGE2 deficiency in the evolution of the fibrotic lesion . - pubmed
We report our management of a neurofibroma of the right auriculotemporal nerve in a 46 - year - old women . - pubmed
Hepatocarcinogenesis inhibition by caffeine in ACI rats treated with 2 - acetylaminofluorene . - pubmed
The purpose of the present study was to examine the inhibitory effect of caffeine on hepatocarcinogenesis and to determine the responsive dose of caffeine on hepatocarcinogenesis in young male ACI rats . - pubmed
Animals given a diet containing 2 - acetylaminofluorene ( 2 - AAF ) for 12 weeks and then a basal diet and tap water containing caffeine for 18 weeks showed statistically significant decreases in the incidence , multiplicity ( the number of hepatic tumors per rat ) and histological grade compared with rats fed a diet containing carcinogen for 12 weeks followed by tap water alone . - pubmed
The inhibitory effect of caffeine on hepatocarcinogenesis in rats was found when caffeine was administered during the initiation phase . - pubmed
The hemodynamic consequences of multifocal atrial tachycardia in an elderly woman are presented . - pubmed
Hormone therapy remains the cornerstone of treatment for patients with locally advanced or metastatic prostate cancer . - pubmed
However , to date there is still no effective therapy for patients who have hormone refractory disease . - pubmed
Clinical evaluation of human placental extract ( placentrex ) in radiation - induced oral mucositis . - pubmed
To evaluate human placental extract in the treatment of radiation mucositis involving the oral / oropharyngeal region , a prospective randomized study was carried out in 120 patients with squamous cell carcinoma of the head and neck from August 1997 to March 1999 . - pubmed
The study was conducted in patients receiving radical external radiation therapy , planned for = & gt ; 60 Gy/30 F/6 weeks , who developed grade 2 radiation mucositis ( patchy mucositis ) during radiation treatment . - pubmed
A subjective decrease in pain was observed in 48/60 ( 80 % ) of patients in the placentrex group compared with 22/60 ( 36.7 % ) in the control group . - pubmed
Human placental extract appears to be effective in the management of radiation - induced oral / oropharyngeal mucositis and especially in controlling subjective symptoms . - pubmed
RESULTS : 21 patients ( 2.0 % ) experienced dislocation after total hip arthroplasty , 17 during activities of daily living and three after a fall . - pubmed
RESULTS : Of the 22 individuals , ataxia was the initial symptom in 21 ; seizure disorders developed in 11 , mostly within several years following the onset of ataxia . - pubmed
A brain magnetic resonance imaging or computed tomographic scan showed cerebellar atrophy in all patients examined . - pubmed
An electroencephalogram demonstrated epileptiform discharges in 4 of 8 patients studied . - pubmed
We hypothesized rhythmic back pressure on a patient in the prone position with sternal counter - pressure ( termed reverse CPR here ) would increase intra - thoracic pressure and in turn systolic blood pressure ( SBP ) during cardiac arrest versus standard CPR . - pubmed
Eligible patients had suffered circulatory arrest and failed standard CPR for at least 30 min . - pubmed
Postnatal protein malnutrition affects inhibitory avoidance and risk assessment behaviors in two models of anxiety in rats . - pubmed
These results suggest that malnourished animals are less anxious and/or more impulsive as measured by these two animal models and that malnutrition seems to affect differently behavioral strategies underlying fear and anxiety responses . - pubmed
OBJECTIVE : To investigate correlation of Helicobacter pylori ( Hp ) infection with symptoms and gastric electrical activity in patients with functional dyspepsia ( FD ) . - pubmed
METHODS : Sixty patients with FD confirmed by gastroscopy and pathology were enrolled in this study . - pubmed
[ Further observations in rabbit fibromatosis induced by Rous virus ] . - pubmed
[ CHANGES IN THE CARDIOVASCULAR SYSTEM OF SUBJECTS WITH ANKYLOSING SPONDYLITIS ] . - pubmed
Quantitative assessment of gastric antrum atrophy shows restitution to normal histology after Helicobacter pylori eradication . - pubmed
The aims of the present study were to evaluate the applicability of this method for the grading of antral atrophy and to study the effect of Helicobacter pylori eradication on the antral mucosa . - pubmed
METHODS : Antrum biopsy specimens were collected from 71 gastroesophageal reflux disease patients at baseline and after 3 and 12 months . - pubmed
The present data indicate that gastric mucosal atrophy is reversible , since almost all cases showed regression of VPGL after H. - pubmed
PURPOSE : To describe central corneal thickness among patients diagnosed with congenital aniridia . - pubmed
METHODS : We identified patients carrying the clinical diagnosis of congenital aniridia and performed complete ophthalmic examinations . - pubmed
This may lead to incorrect estimates of intraocular pressure by applanation techniques and highlights the importance of monitoring patients with aniridia for the development of glaucoma through regular gonioscopy and optic nerve examination . - pubmed
Management of a patient with a forearm fracture and median nerve injury . - pubmed
OBJECTIVES : Patients with peripheral nerve injury may demonstrate long - lasting impairments and functional limitations . - pubmed
In this case report , we describe the diagnosis of a patient with a peripheral nerve injury and a conventional plan of care , along with the novel intervention of neuromuscular electrical stimulation ( NMES ) . - pubmed
BACKGROUND : The patient was a 21 - year - old male who sustained a forearm fracture that was complicated by injury to the anterior interosseous branch of the median nerve . - pubmed
Infection of man with Bacterium tularense . - pubmed
Myocardial viability in patients with ischemic cardiomyopathy - evaluation by 3 - D integration of myocardial scintigraphic data -- and coronary angiographic data . - pubmed
PURPOSE : To determine the prevalence of viable myocardium in patients with ischemic cardiomyopathy and , to evaluate the value of three - dimensional ( 3 - D ) fusion imaging of myocardial scintigraphic and angiographic data to assign coronary artery lesions to the corresponding viable and nonviable myocardial territory . - pubmed
RESULTS : Based on the presence of viable dysfunctional myocardium , 54 % of patients with ischemic cardiomyopathy may be considered for coronary revascularization . - pubmed
CONCLUSION : In patients with end - stage coronary artery disease scintigraphic imaging is most important in the decision - making process . - pubmed
Here we report that in mouse fusiform cells , spikes evoked 5 ms after parallel - fiber excitatory postsynaptic potentials ( EPSPs ) led to long - term potentiation ( LTP ) , whereas spikes evoked 5 ms before EPSPs led to long - term depression ( LTD ) of the synapse . - pubmed
Thyrotoxicosis remains a frustrating condition for the young person , family , and health professionals involved . - pubmed
Most patients with thyrotoxicosis will need many years of drug therapy if the thyroid gland is not removed surgically or destroyed by radioiodine . - pubmed
Successful use of intralesional and intravenous cidofovir in association with indole-3 - carbinol in an 8 - year - old girl with pulmonary papillomatosis . - pubmed
We report the history of an 8 - year - old girl who was treated for suspected lung lesions of respiratory papillomatosis with Indole-3 - Carbinol , local and intravenous injections of Cidofovir for 27 months . - pubmed
This is the first report where a complete cure of the lung lesions occurred in a child , and was sustained for at least 24 months . - pubmed
METHODS : NDL was performed in 108 patients unselected for breast carcinoma risk and then was repeated after 2 - 14 months ( median , 8 months ) if the initial lavage was classified as atypical . - pubmed
After excluding breasts with an incident carcinoma , there were 32 patients ( 30 % ) with either mild or marked atypia . - pubmed
Virological and molecular characterization of a mammalian orthoreovirus type 3 strain isolated from a dog in Italy . - pubmed
A mammalian orthoreovirus ( MRV ) strain was isolated from a pup with fatal diarrhea , which had a concurrent infection by canine parvovirus type 2 . - pubmed
A total of 110 fecal samples , 56 nasal and 31 ocular swabs from dogs with diarrhea or nasal / ocular discharge were tested by a nested - PCR assay specific for reoviruses , and no sample was found to contain MRV RNA , a finding that is apparently in contrast with the seroprevalence ( 25.77 % ) observed in dogs . - pubmed
The hESC - derived NK cells acquire the ability to lyse human tumor cells by both direct cell - mediated cytotoxicity and Ab - dependent cellular cytotoxicity . - pubmed
It was found that the excess of cardiovascular events and mortality occurs already in diabetic patients with persistent microalbuminuria , but is particularly evident in macroalbuminuric diabetic patients and results not only from end - stage renal failure ( ESRF ) but rather from cardiovascular disease ( CVD ) , the latter mainly in type 2 diabetic patients . - pubmed
Several traditional risk factor for atherosclerosis has been identified in diabetic patients with micro- or macroalbuminuria including elevated blood pressure levels , dyslipidemia and procoagulatory state associated with endothelial dysfunction . - pubmed
Thus , multiple mechanisms are involved in the development and progression of cardiovascular complications both in micro- and macroalbuminuric diabetic patients and all these mechanisms should be regarded as the target for therapeutic intervention . - pubmed
The causal analysis showed a depressed baroreflex regulation in resting patients , with reduced gain and increased latency from SP to RR , and a drop of the baroreflex coupling immediately before syncope . - pubmed
Most patients die from distant metastases , and the overall 5 year survival rate is approximately 4 % . - pubmed
CONCLUSION : This supports the concept that patients with primary melanoma of the oesophagus treated should be carefully followed up . - pubmed
Three of 300 ( 1 % ) PD patients presented with HFS compared with 0/300 ( 0 % ) controls . - pubmed
The mean age of the three PD patients with HFS was 68.7 + /- 8.0 ( 60 - 76 ) years , with the majority having left - sided HFS . - pubmed
All three patients developed HFS symptoms at around the onset of PD and they were significantly older than the 100 patients with HFS alone ( P < 0.05 ) . - pubmed
Our study demonstrated no significant increased risk of HFS amongst the general PD population and hence HFS symptoms are unlikely to be of clinical importance for most PD patients . - pubmed
Rosiglitazone could improve clinical outcomes after coronary stent implantation in nondiabetic patients with metabolic syndrome . - pubmed
BACKGROUND : Recent studies have shown that thiazolidinediones ( TZDs ) could reduce in - stent restenosis and improve clinical outcomes in patients with type 2 diabetes after coronary stent implantation . - pubmed
It remains unclear whether nondiabetic patients with metabolic syndrome after stenting could also benefit from the treatment with TZDs . - pubmed
METHODS : Three hundred and sixty patients with metabolic syndrome who underwent coronary stent implantation were randomly assigned to a rosiglitazone group ( n = 180 ) or a control group ( n = 180 ) . - pubmed
CONCLUSION : Rosiglitazone could reduce the risk of the adverse cardiovascular event and improve clinical outcomes in nondiabetic patients with metabolic syndrome after coronary stent implantation . - pubmed
A child with liver kidney microsomal ( LKM ) antibody positivity underwent successful liver transplantation for liver failure secondary to GCH with Coomb 's positive hemolytic anemia . - pubmed
PATIENTS AND METHODS : Pancreas - sparing distal duodenectomy ( PSDD ) was performed in 14 patients with infrapapillary duodenal neoplasms between 1991 - 2002 , and the clinical outcome is reviewed . - pubmed
RESULTS : There were 9 men and 5 women of median age 56 years , who presented with iron - deficiency anaemia ( n = 8) , gastric outlet obstruction ( n = 4 ) , anaemia and gastric outlet obstruction ( n = 1 ) , epigastric pain or mass ( 1 each ) . - pubmed
There were 11 malignant neoplasms ( adenocarcinoma 5 , stromal tumour 4 , recurrent seminoma 1 , plasmacytoma 1 ) , 2 benign neoplasms ( villous adenoma , lipoma ) and 1 patient with steroid - induced ulceration . - pubmed
CONCLUSIONS : Provided there is a minimum 1 - cm clearance at the papilla , PSDD is a useful alternative to formal pancreatoduodenectomy in patients with unusual neoplasms arising from the third and fourth parts of the duodenum . - pubmed
Genotyping glycogen storage disease type II and type V in cattle reared in the Czech Republic . - pubmed
Genotyping was carried out for glycogen storage disease type II and type V in seven cattle breeds . - pubmed
Of the symptomatic patients , 14.0 % had atherothrombotic lesions in more than 1 vascular bed , with 0.8 % having lesions in 3 areas : brain , heart , and peripheral arteries . - pubmed
Helminths down - regulate inflammation and may prevent development of several autoimmune illnesses , such as inflammatory bowel disease . - pubmed
PURPOSE OF REVIEW : Patients treated for cancer may be at risk for osteoporosis and fracture . - pubmed
Evaluation and treatment of patients with cancer treatment - induced bone loss should lead to fewer fractures . - pubmed
This review will help clinicians learn to identify , evaluate and treat cancer patients at risk . - pubmed
RECENT FINDINGS : Survivors of childhood cancers and patients made hypogonadal by treatment for breast or prostate cancer are clearly at risk for osteoporosis and fracture . - pubmed
Bisphosphonates prevent bone loss in many patients at risk . - pubmed
SUMMARY : For many cancer patients , treatment with calcium , vitamin D , and bisphosphonates will likely decrease the consequences of cancer treatment - induced bone loss , namely fractures . - pubmed
In this work , we evaluate the significance of disease extent in a group of patients with CIN 2 to 3 that was completely excised by LEEP ( ie , endocervical and ectocervical margins were negative ) . - pubmed
A sustained - release formulation of doxycycline hyclate ( Atridox ) prevents simultaneous infection of Anaplasma phagocytophilum and Borrelia burgdorferi transmitted by tick bite . - pubmed
MATERIALS AND METHODS : we studied 163 patients ( mean age 65.5 years ; 101 men and 62 women ) referred for multidetector computed tomography coronary angiography ( MDCT - CA ) to rule out CAD . - pubmed
Plaque in patients with nonsignificant disease was mixed in 65 % , soft in 18 % and calcified in 17 % . - pubmed
Doxorubicin - based chemotherapy for the palliative treatment of adult patients with locally advanced or metastatic soft - tissue sarcoma : a meta - analysis and clinical practice guideline . - pubmed
To make recommendations for the use of doxorubicin - based chemotherapy in patients with soft - tissue sarcoma . - pubmed
The recommendations apply to patients with symptomatic unresectable locally advanced or metastatic soft - tissue sarcoma who are candidates for palliative chemotherapy . - pubmed
Systemic aminoglycoside treatment in rodent models of retinitis pigmentosa . - pubmed
[ Use of mebendazole for helminthiases in chickens and geese ] . - pubmed
Two groups of geese , 20 in each group , were treated against Hymenolepis - infection using Mebendazol in food for 6 consecutive days . - pubmed
In vivo studies and histopathological examination revealed that eyes of rabbits treated with nanoemulsion showed clearer healing of corneal chemical ulcer with moderate effective inhibition of polymorph nuclear leukocytic infiltration ( PMNLs ) compared with nanoparticles preparation . - pubmed
Bleb leakage was the most common complication in each group and developed in approximately 4 % of subjects in each group per year ( P = 0.33 , log - rank test ) . - pubmed
Clinical assessment of peripheral muscle function in patients with chronic obstructive pulmonary disease . - pubmed
DESIGN : Sixteen COPD patients ( forced expiratory volume during the first second 38 + /- 15 % predicted ) and 6 controls underwent magnetic resonance imaging of the thigh , muscle strength and endurance , and exercise tolerance assessments . - pubmed
Six COPD patients ( 16 + /- 2.5 kg m(-2 ) ) ( P & lt ; 0.05 ) presented reduced thigh mass ( COPDLQ ) , whereas 10 patients with normal quadriceps mass ( COPDNQ ) and all controls had identical mass distribution ( 22 + /- 2.4 kg m(-2 ) ) . - pubmed
COPDLQ patients had lower muscle function and lower exercise tolerance than both COPDNQ and controls ( P & lt ; 0.05 each ) , but muscle strength corrected by mass was similar between COPD patients ( COPDLQ 0.59 + /- 0.12 and COPDNQ 0.55 + /- 0.10 Nm kg(-1 ) m(-2 ) ) and controls ( 0.62 + /- 0.04 Nm Kg(-1 ) m(-2 ) ) . - pubmed
CASE REPORT : A 16 - year - old woman developed a sudden onset of dystonic symptoms which affected her higher and lower limbs , bulbar muscles , together with severe dysarthria and dysphagia . - pubmed
The proteasome inhibitor bortezomib has a striking clinical benefit in patients with multiple myeloma . - pubmed
We have used the well - characterized 5TGM1 murine model of myeloma to investigate myeloma growth within bone and response to the proteasome inhibitor bortezomib in vivo . - pubmed
Myeloma cells freshly isolated from the bone marrow of myeloma - bearing mice were found to have an increase in proteasome activity and an enhanced response to in vitro proteasome inhibition , as compared with pre - inoculation myeloma cells . - pubmed
Treatment of myeloma - bearing mice with bortezomib resulted in a greater reduction in tumor burden when the myeloma cells were located within the bone marrow when compared with extra - osseous sites . - pubmed
Two patients received superficial second - degree burns that did not require corrective treatment . - pubmed
paratuberculosis is an important pathogen that causes Johne ' s disease in animals and also has been implicated as a possible cause of Crohn ' s disease in humans , but little is known about the protective immune responses to this microorganism . - pubmed
Using mouse models , we determined the contribution of DCs to altered hepatic immunity in fibrosis and investigated the role of DCs in modulating the inflammatory environment within the fibrotic liver . - pubmed
OBJECTIVE : To investigate the recurrence of the neck and survival incidence of clinically possible positive lateral cervical nodes in patients with well - differentiated papillary thyroid cancer and the essentiality of the perforation of modified radical neck dissection . - pubmed
RESULT : Fifty nine patients in group A were treated with the modified radical neck dissection , and 22 patients of them were found metastasis in lateral cervical nodes with VI area . - pubmed
47 patients in group B had metastasis in lateral cervical nodes though without performing VI area neck dissection ( 40.5 % ) , and the survival rate of 5 years was 99.3 % . - pubmed
Worldwide , there are several approaches for the prevention of cervical cancer , and in the near future it is likely that human papillomavirus ( HPV ) vaccination and HPV - based screening will be complementary strategies . - pubmed
HPV vaccination programs targeted at young girls have been widely implemented in several affluent countries , and currently available data confirm the long - term efficacy of the VLP - based vaccines against HPV - related disease over periods of up to 8 years . - pubmed
However , a significant HPV vaccination - induced reduction in cervical cancer burden is not likely to be realized for at least 10 to 15 years . - pubmed
BACKGROUND : Deep amblyopia is a recognized cause of monocular visual deficit in children with a high rate of poor compliance with conventional occlusion therapy . - pubmed
This study evaluates a new occlusion technique that can be used for children with failed amblyopia treatment . - pubmed
METHODS : In a prospective study , surgical silicone - eyelid closure was done for 15 children ( age : 4 to 6 years ; median age : 5.2 years ) with a history of deep amblyopia and poor compliance with occlusion methods . - pubmed
Complications were seen in 8 patients : marginal eyelid irritation and erythema in 6 and suture break in 2 . - pubmed
TRial of an Educational intervention on patients ' knowledge of Atrial fibrillation and anticoagulant therapy , INR control , and outcome of Treatment with warfarin ( TREAT ) . - pubmed
DISCUSSION : More data is needed on the clinical benefit of educational intervention with AF patients receiving warfarin . - pubmed
One of the least studied but most important areas in this regard is the effects of embryo culture on epigenetic phenomena , and on genomic imprinting in particular , because assisted reproduction has been linked to development of the human imprinting disorders Angelman and Beckwith - Wiedemann syndromes . - pubmed
Patients with nondiploid tumors had higher hazard rates for both tumor progression and death ( p = 0.007 and p = 0.016 , respectively ) ; however , the prognostic information of DNA ploidy was not additive to tumor grade . - pubmed
We studied 282 patients with CAD without ST elevation and preserved systolic function . - pubmed
No statistically significant difference was observed between patients with SA and controls ( 21.2 + -6.8 pg / mL ) . - pubmed
Improvements of cardiac electrophysiologic stability and ventricular fibrillation threshold in rats with myocardial infarction treated with cardiac stem cells . - pubmed
We sought to investigate the electrophysiologic characteristics and ventricular fibrillation threshold in rats with myocardial infarction by treatment with allogeneic cardiac stem cells . - pubmed
INTERVENTIONS : Myocardial infarction was induced in 20 male Sprague - Dawley rats . - pubmed
CONCLUSIONS : Cardiac stem cells may modulate the electrophysiologic abnormality and improve the ventricular fibrillation threshold in rats with myocardial infarction treated with allogeneic cardiac stem cells and cardiac stem cell express markers that suggest muscle , endothelium , and vascular smooth muscle phenotypes in vivo . - pubmed
Atrial electromechanical interval can identify patients with paroxysmal atrial fibrillation and is associated with CHADS2 score and peak velocity of left atrial appendage . - pubmed
INTRODUCTION : It is difficult to discriminate patients with and without paroxysmal atrial fibrillation ( PAF ) . - pubmed
The aim of our study was to investigate whether the electromechanical interval is a useful parameter to identify patients with PAF . - pubmed
METHODS AND RESULTS : A total of 297 patients ( PAF group = 103 ; control group = 194 ) with mean age of 59.4 + - 12.4 years were enrolled . - pubmed
Investigation of human JC and BK polyomaviruses in breast carcinomas . - pubmed
We have previously showed the presence of the simian virus 40 ( SV40 ) and the mouse mammary tumor virus ( MMTV)-like in a significant proportions of Tunisian breast carcinomas . - pubmed
However , to date there are no published studies concerning evaluation of the possible implication of the human polyomaviruses JC ( JCV ) and BK ( BKV ) in breast carcinomas . - pubmed
The presence of JCV and BKV DNA was investigated by PCR in a 123 primary breast carcinomas and matched adjacent non - tumor breast tissues . - pubmed
JCV T - antigen DNA was detected in 23 % of breast carcinoma cases ; however , all cases were negative for BKV . - pubmed
To the best of our knowledge , this is the first study demonstrating the presence of JCV in a subset of breast carcinomas . - pubmed
The second patient was a 76 - year old male , moderate smoker and drinker , who had been complaining about swelling in the neck . - pubmed
Cerebral hypoperfusion and white matter disease in healthy elderly and patients with Alzheimer ' s disease . - pubmed
PURPOSE : To compare the clinical results and repair integrity of arthroscopic rotator cuff repair between a knotless and a conventional knot - tying suture bridge technique for patients with full - thickness rotator cuff tears and to evaluate retear patterns in the cases with structural failure after arthroscopic repair by magnetic resonance imaging ( MRI ) . - pubmed
METHODS : After arthroscopic repair for medium - sized rotator cuff tears , 110 patients available for postoperative MRI evaluation at least 6 months were enrolled in this study . - pubmed
Representativeness of the dabigatran , apixaban and rivaroxaban clinical trial populations to real - world atrial fibrillation patients in the United Kingdom : a cross - sectional analysis using the General Practice Research Database . - pubmed
OBJECTIVE : Three oral anticoagulants have reported study results for stroke prevention in patients with atrial fibrillation ( AF ) ( dabigatran etexilate , rivaroxaban and apixaban ) ; all demonstrated superiority or non - inferiority compared with warfarin ( RE - LY , ARISTOTLE and ROCKET - AF ) . - pubmed
RESULTS : 83 898 patients with AF were identified in the GPRD . - pubmed
Preperimetric glaucoma patients had significant reductions of ONH perfusion compared to normals . - pubmed
Porcine parvovirus ( PPV ) is a major causative agent of reproductive failure in swine , which currently affects the swine industry worldwide . - pubmed
These mechanistic studies of fiber toxicity have proceeded along two lines : those demonstrating biochemical mechanisms by which fibers induce disease and those investigating human susceptibility . - pubmed
Although asbestos exerts a genotoxic effect at certain concentrations in vitro , a positive response in these tests does not indicate that the chemical is likely to produce an increased risk of carcinogenesis in exposed human populations . - pubmed
Altogether 257 obese children and adolescents ( RBMI>120 ) and 94 adults , who were never obese or overweight ( BMI<25 ) , were studied . - pubmed
A 16 - year - old woman with MELAS developed fever and myoclonic epilepsy which improved with conventional anti - epileptic drugs . - pubmed
Use of NSAIDs in treating patients with arthritis . - pubmed
In patients with risk factors for NSAID toxicity , using the lowest dose of a drug with a short half - life only when it is needed is likely to be the safest treatment option . - pubmed
These results provide new insight into the mechanism by which the seahorse - derived peptide suppresses invasive properties of human cancer cells . - pubmed
Erythroderma is generalized exfoliative dermatitis , which involves more than 90 % of the patient 's skin . - pubmed
Clinically , the patients presented with non - specific symptoms such as chest pain , or were entirely asymptomatic . - pubmed
None of the patients had a history of autoimmune syndrome . - pubmed
We retrospectively reviewed 91 focal cortical dysplasia patients ( 55 % female ; median age : 19 years ( interquartile range 8 - 34 ) ; median seizure duration : 108 months ( interquartile range 36 - 204 ) ) with chronic epilepsy who underwent surgery . - pubmed
Of the 91 patients , there were 50 patients with ILAE focal cortical dysplasia type Ib , 41 with ILAE focal cortical dysplasia type Ic , 63 with Palmini et al focal cortical dysplasia type IA , and 28 with Palmini et al focal cortical dysplasia type IB . - pubmed
Patients with pSS were classified accordingly with the grade of inflammatory lesions as I = low - grade ( low focus score of 1 or 2 ) , II = intermediate - grade ( focus score of 3 - 6 ) and III = extensive inflammation in the MSG ( high focus score of 12 ) . - pubmed
At P12 , cKO mice exhibited cardiac hypertrophy and impaired contraction of the left ventricle . - pubmed
While this works well for cell culture studies and leukaemia mouse models , fluorescent reporters are poorly suited for animals with solid tumours -- the most common tumour types in cancer patients . - pubmed
We demonstrate that secreted luciferase activities can be measured robustly in the blood stream of tumour - bearing mice to accurately quantify , in a minimally invasive manner , the dynamic evolution of two genetically distinct tumour subclones in preclinical mouse models of tumour development , metastasis and therapy . - pubmed
Among 14,411 transplanted patients the incidence of BCs was 23 % . - pubmed
Since the completion of the human genome project and with the increased availability of high - throughput genotyping , multiple genetic risk factors for substance - related disorders , including alcohol dependence , have been identified , but not all results could be replicated . - pubmed
OBJECT : While the incidence of a recurrent hemorrhage is highest within 24 hours of subarachnoid hemorrhage ( SAH ) and increases with the severity of the clinical grade , a recurrent hemorrhage can occur anytime after the initial SAH in patients with both good and poor clinical grades . - pubmed
Therefore , the authors adopted a 24 - hour - a - day , formal protocol , emergency treatment strategy for patients with ruptured aneurysms to secure the aneurysms as early as possible . - pubmed
METHODS : During an 11 - year period , a total of 1224 patients with a ruptured aneurysm were managed using a strategy of broadly defined early treatment between 2001 and 2004 ( Period B , n=423 ) , a mixture of early or emergency treatment between 2005 and 2007 , and a formal emergency treatment protocol between 2008 and 2011 ( Period A , n=442 ) . - pubmed
CONCLUSIONS : Patients with ruptured aneurysms may benefit from a strategy of emergency application of surgical clip placement or endovascular coiling due to the reduced incidence of recurrent bleeding and improved clinical outcomes . - pubmed
Of the 3445 eligible persons ( mean age 72.0 + -7.1 years ) available for cross - sectional analyses , 8.9 % ( n = 307 ) had prevalent clinical heart failure . - pubmed
In longitudinal analyses , 1989 eligible persons ( mean age 70.0 + -5.8 years ) were followed for an average of 6.5 + -0.4 years , of which 4.6 % ( n = 91 ) had prevalent or incident clinical heart failure . - pubmed
Medial epicondyle fractures in children . - pubmed
In patients with displaced fractures , fixation yields stability , functional range of motion , and the ability to return to previous activity levels , including sports . - pubmed
We present a case of a 9 - year boy who accidentally ingested a long paper pin , which spontaneously passed in 26 h. This case is being reported to highlight the successful spontaneous passage of a 4 cm long sharp foreign body in a child . - pubmed
We aimed to investigate the effect of probable risk factors on the positive rate of the repeated transurethral resection of bladder tumor performed 4 - 6 weeks after an initial TURBT in patients with non - muscle invasive bladder cancer in China . - pubmed
METHODS : 134 patients with non - muscle invasive bladder cancer who underwent repeated TURBT within 4 - 6 weeks after an initial resection were included in this study . - pubmed
As showed in the manuscript , of the total 134 patients , 52 had residual tumor , and upgrading occurred in 41 patients . - pubmed
The progression and recurrence rate was significantly higher in patients with residual tumor in Re TURBT . - pubmed
OBJECTIVE : As part of the Physicians ' Observational Work on Patient Education According to their Vascular Risk ( POWER ) survey , we used Framingham methodology to examine the effect of an eprosartan - based regimen on total coronary heart disease ( CHD ) risk in diabetic patients recruited in Canada . - pubmed
METHODS : Patients with new or uncontrolled hypertension ( sitting systolic blood pressure [ SBP ] & gt;140 mmHg with diastolic blood pressure & lt;110 mmHg ) were identified at 335 Canadian primary care practices . - pubmed
RESULTS : We identified an intention - to - treat diabetes population of 195 patients . - pubmed
Most diabetic patients were prescribed two or more antihypertensive drugs throughout the survey . - pubmed
Intermuscular fat increased with weight loss , weight gain , or with no weight change with age in humans . - pubmed
The relationship between leanness and higher proportions of INTMF fat in pigs was not observed in human studies and was not corroborated by other pig studies . - pubmed
Lipin1 deficiency results in immature adipocyte development in human lipodystrophy . - pubmed
Moreover , the designed SHPE apparatus demonstrates potential application in wound dressing by in situ e - spinning fibers onto human skin directly . - pubmed
White matter volume in the brainstem and inferior parietal lobule is related to motor performance in children with autism spectrum disorder : A voxel - based morphometry study . - pubmed
In this study , we used voxel - based morphometry ( VBM ) to investigate which WM regions correlate with motor performance in children with ASD , and whether the WM volume in those brain regions differed between children with ASD and typically developing ( TD ) children . - pubmed
The subjects included 19 children with ASD and 20 TD controls . - pubmed
Children with ASD showed poorer motor performance than did the controls . - pubmed
These findings suggest that structural changes in the WM in the brainstem and left inferior parietal lobule may contribute to poor motor performance in children with ASD . - pubmed
However , these benefits are not obvious in cardiac surgery patients with intraoperative anemia . - pubmed
Similarly , postoperative complications did not differ between patients who received a red cell transfusion and matched patients who did not ( adjusted odds ratio 0.94 , confidence interval 0.72 - 1.23 ) . - pubmed
Occipital nerve stimulation ( ONS ) is a surgical approach to treat patients with medically intractable chronic headache disorders . - pubmed
In this study , the analgesic efficacy of transcutaneous electrical nerve stimulation ( TENS ) was tested for 1 to 3 months in 41 patients with pharmacologically intractable headache disorders of various origins , using a new technique of electrode placement over the occipital nerve . - pubmed
ONS electrodes were subsequently implanted in 33 patients ( occipital neuralgia [ n=15 ] , cervicogenic headache [ n=7 ] , cluster headache [ n=6 ] , chronic migraine [ n=5 ] ) who had responded at least moderately to TENS . - pubmed
Implanted ONS may be a valuable therapeutic option in the long term for patients with pharmacologically intractable chronic headache . - pubmed
This preoperative test could particularly be useful in patients with chronic migraine , in whom it may be difficult to indicate an invasive technique of cranial neurostimulation . - pubmed
Stromal cells with a myofibroblast phenotype present in the normal human esophagus are increased in individuals with gastro - esophageal reflux disease ( GERD ) . - pubmed
The antimicrobial activity as well as the cytotoxicity were specific for the different test microorganisms ( Gram - positive and Gram - negative bacteria and fungi ) and model eukaryotic cells ( osteosarcoma , fibroblast , and keratinocyte cells ) , respectively , and both were depending on the ZnTiO3 concentration . - pubmed
BACKGROUND : Surgery remains the standard of care for patients with colorectal liver metastases ( CLMs ) , with a 5 - year survival rate approaching 35 % . - pubmed
Perioperative chemotherapy confers a survival benefit in selected patients with CLMs . - pubmed
Airborne Fine Particulate Matter Induces Oxidative Stress and Inflammation in Human Nasal Epithelial Cells . - pubmed
Exposure to PM2.5 is associated with increased risk of many human diseases , including chronic and allergic rhinitis , but the underlying molecular mechanism for its toxicity has not been fully elucidated . - pubmed
These results suggest that PM2.5 may induce oxidative stress and inflammatory responses in human nasal epithelial cells , thereby leading to nasal inflammatory diseases . - pubmed
Contribution of the patient - horse relationship to substance use disorder treatment : Patients ' experiences . - pubmed
Few have reported on the patient 's own perspective and none have reported specifically on the human - horse relationship in substance use disorder ( SUD ) treatment and its implications for health and well - being . - pubmed
The objective of the present study was to characterize the liver oil extracted from the deep sea shark , Echinorhinus brucus , caught from Central Indian Ocean and to evaluate its cytotoxic effect on neuroblastoma cell line ( SHSY-5Y ) . - pubmed
The oil of Echinorhinus brucus also showed high in vitro cytotoxic effect against the human neuroblastoma cell line ( SHSY-5Y ) and the IC50 value laid between 35 and 45 ng . - pubmed
METHODS : The records of 80 trauma patients admitted to the Anaesthesia , General Surgery and Neurosurgery ICUs between June 1 , 2012 and July 15 , 2014 were included in the study . - pubmed
CONCLUSION : The most important factor affecting mortality in this particular trauma - ICU patient population from Syrian civil war was the physiological condition of patients on admission . - pubmed
Genital tract lesions in sexually mature Gottingen minipigs during the initial stages of experimental vaginal infection with Chlamydia trachomatis serovar D. BACKGROUND : Chlamydia is one of the most common sexually transmitted diseases in humans worldwide , causing chronic lesions in the reproductive tract . - pubmed
This study employs a novel sexually mature minipig model to investigate the initial histopathological changes following vaginal infection with Chlamydia trachomatis serovar D. RESULTS : A vaginal inoculation resulted in an infection primarily affecting the lower genital tract . - pubmed
In this study , we observe a similar pattern of local immune response / inflammation following experimental inoculation suggesting this porcine model shows promise as a model for translational chlamydia research . - pubmed
ILC2s as key players in the development of allergic rhinitis ( AR ) have been proved , however , the effect of subcutaneous immunotherapy ( SCIT ) with dermatophagoides pteronyssinus extract ( Der p - SCIT ) on ILC2s in AR patients is not clear . - pubmed
This study aimed to investigate the response of ILC2s of peripheral blood in house dust mites ( HDM)-sensitized Chinese patients with AR who received SCIT with Der P extract . - pubmed
RESULTS : Among 40 participants , 9 AR patients were assigned to the untreated group , 24 AR patients receiving Der p - SCIT were assigned to the immunotherapy group , and 7 healthy controls without symptoms of AR were assigned to healthy control group . - pubmed
CONCLUSIONS : The present study highlighted the suppression of Der p - SCIT on ILC2s in HDM - AR patients . - pubmed
METHODS : Fifty - three patients with NERD , who had persistent reflux symptoms despite taking double - dose PPI , were included in this study . - pubmed
RESULTS : One of the 53 patients had EoE , and 4 had primary esophageal motility disorder . - pubmed
The main determinant of disease progression is efficiency of the CTL response to Human T lymphotropic virus types I ( HTLV-1 ) . - pubmed
Based on case numbers and the potential impact on human health , the Centers for Disease Control and Prevention ( CDC ) categorised toxocarosis as one of the most important neglected parasitic diseases . - pubmed
METHODS : We retrospectively reviewed 62 consecutive Lenke 1 AIS patients who underwent posterior spinal arthrodesis using all - pedicle screw instrumentation with a minimum follow - up of 24 months . - pubmed
CONCLUSIONS : Both low density and high density pedicle screw instrumentation achieved satisfactory deformity correction in Lenke 1 AIS patients . - pubmed
Seven and 10 patients had preoperative anemia in the MI - TLIF group and the O - TLIF group , respectively , and 32 and 45 postoperatively . - pubmed
A correct understanding of HBL can ensure patient safety and improve postoperative rehabilitation . - pubmed
Methods : From January 2014 to October 2016 , Eighty - four patients with stenosing tenosynovitis were randomly divided into the open decompressionand group ( 42 cases ) and percutaneously looped thread transection group ( 42 cases ) in Department of Orthopedics , Affiliated Laiwu Hospital of Taishan Medical College . - pubmed
A phase 3 , double - blind , randomized placebo - controlled efficacy and safety study of abiraterone acetate in chemotherapy - naive patients with mCRPC in China , Malaysia , Thailand and Russia . - pubmed
Objective : This double - blind , placebo - controlled phase 3 study was designed to compare efficacy and safety of abiraterone acetate + prednisone ( abiraterone ) to prednisone alone in chemotherapy - naive , asymptomatic or mildly symptomatic metastatic castration - resistant prostate cancer ( mCRPC ) patients from China , Malaysia , Thailand and Russia . - pubmed
Conclusion : Interim analysis confirmed favorable benefit - to - risk ratio of abiraterone in chemotherapy - naive men with mCRPC , consistent with global study , thus supporting use of abiraterone in this patient population . - pubmed
BACKGROUND : Mechanisms for the development of food allergy in neonates are unknown but clearly linked in patient populations to a genetic predisposition to skin barrier defects . - pubmed
After sensitization , mice received oral challenge with food allergen , and then inflammation , inflammatory mediators , and anaphylaxis were measured . - pubmed
RESULTS : We define development of inflammation , inflammatory mediators , and food allergen - induced anaphylaxis in neonatal mice with skin barrier mutations after brief concurrent cutaneous exposure to food and environmental allergens . - pubmed
CONCLUSION : These studies uncover mechanisms for food allergy sensitization and anaphylaxis in neonatal mice that are consistent with features of human early - life exposures and genetics in patients with clinical food allergy and demonstrate that changes in barrier function drive development of anaphylaxis to food allergen . - pubmed
METHODS : We conducted a retrospective study , which included CML patients , who were above 18 years of age and who until May 2013 had used at least for 2 years ( 24 months ) the original imatinib , and following that used at least for 24 months one of the generic imatinib medicines . - pubmed
DNA methylation of genes regulating appetite and prediction of weight loss after bariatric surgery in obese individuals . - pubmed
RESULTS : At baseline , type 2 diabetes was diagnosed by OGTT in 13 patients . - pubmed
Further evidence for depletion of peripheral blood natural killer cells in patients with schizophrenia : A computational deconvolution study . - pubmed
Our analysis was based on publicly available data from peripheral blood DNA methylation profiling in 711 schizophrenia patients and 713 healthy controls ( 2 independent samples ) . - pubmed
METHODS : Two hundred fifty - three patients with metastatic breast cancer were enrolled in this prospective , multicentre study . - pubmed
OMWW dietary supplementation can be a nutritional strategy to improve chicken performance and health , prevent intestinal damage , enhance innate immunity and regulate cholesterol metabolism and fat deposition . - pubmed
After examining each potential risk factor in a separate multivariable model , only Day-10 surrogate Hospital Anxiety and Depression Scale score ( beta coefficient = 1.02 ; 95 % CI , 0.73 - 1.30 ) and patient unresponsiveness ( beta coefficient = 8.39 ; 95 % CI , 0.83 - 15.95 ) were associated with higher IES - R scores . - pubmed
CONCLUSIONS : Among surrogate decision - makers for chronically critically ill patients , high anxiety and depression scores and patient unresponsiveness on or near Day 10 of mechanical ventilation are risk factors for PTSD symptoms at 90 days . - pubmed
Included patients had & gt;=12 months of serial creatinine laboratories and a baseline estimated glomerular filtration rate ( eGFR , by the Modification of Diet in Renal Disease Study equation ) & gt;=60 mL / min/1.73 m2 . - pubmed
RESULTS : Adjusted mean eGFR was significantly higher for non - CHB vs. untreated CHB patients ( eGFR 87.4 vs. 85.6 , P= 0.004 , n = 580 , median follow - up = 82 months ) . - pubmed
A significant difference in adjusted mean eGFR between untreated vs. entecavir ( ETV)-treated CHB patients ( eGFR 85.1 vs. 83.5 , P= 0.02 , n = 340 , median follow - up = 70 months ) was found among non - cirrhotic CHB . - pubmed
Among treated CHB , there was no difference in adjusted mean eGFR between non - cirrhotic vs. cirrhotic patients ( eGFR 77.0 vs. 76.5 ; P= 0.66 , n = 112 , median follow - up = 58 months ) . - pubmed
Methods : The present randomized , clinical trial study was conducted on 82 women who complained of hot flashes during their menopause period . - pubmed
Urgent TAVR was defined as a procedure performed in the same hospitalization in patients emergently admitted due to cardiac arrest , severe acute decompensated heart failure , acute coronary syndrome , or repeated syncopal episodes . - pubmed
Materials and methods Gastric subepithelial lesions in multiple topographic locations of the stomach were simulated in seven live pigs . - pubmed
Only individuals at risk for vitamin D deficiency should be screened . - pubmed
Deregulation of metallothionein genes has been reported in various human tumors . - pubmed
METHODS : Fourteen eyes of 14 patients diagnosed with type 3 neovascularization were studied . - pubmed
We included all patients from the years 2006 to 2018 with severe frostbite injury who had received appropriate imaging for diagnosis : Tc99 scan alone ( N = 82 ) , microangiography alone ( N = 22 ) , and both Tc99 and microangiography ( N = 26 ) . - pubmed
Environmental and occupational exposure to industrial chemicals has been linked to toxic and carcinogenic effects in animal models and human studies . - pubmed
CASE REPORT We present the case of a 67 - year - old woman with subacute cutaneous lupus erythematosus ( SCLE ) and EM - like lesions who fulfilled all the criteria for Rowell ' s syndrome . - pubmed
The patient had lupus arthritis for two years and was treated with oral methylprednisolone 8 mg / day and hydroxychloroquine 200 mg / day . - pubmed
The patient also had arterial hypertension with no current treatment , osteoporosis , and an L1 vertebral fracture . - pubmed
and ceftriaxone 2 g / day for the superinfection with Ps . - pubmed
We present a case of metastatic melanoma in a 69 - year - old man as the underlying etiology of his intussusception . - pubmed
The patient remains alive without recurrence . - pubmed
BET 1 : Efficacy of different techniques using a metered - dose inhaler with Spacer to relieve symptoms in children with acute asthma . - pubmed
Resveratrol , a natural plant product , has been found to exert anti - inflammatory properties and attenuate the development of murine colitis . - pubmed
Lastly , analysis of public data from human patients with ulcerative colitis ( UC ) revealed that miR-31 expression was significantly increased when compared to controls . - pubmed
CONCLUSIONS : Together , the current study demonstrates that resveratrol - mediated attenuation of colitis may be regulated by miR-31 through induction of Tregs and miR-31 may serve as a therapeutic target for human colitis . - pubmed
Sensitization of spinal itch transmission neurons in a mouse model of chronic itch requires an astrocytic factor . - pubmed
BACKGROUND : Chronic itch is a highly debilitating symptom among patients with inflammatory skin diseases . - pubmed
Interestingly , increases in excitation were attenuated by suppressing the reactive state of SDH astrocytes , which are known to be reactive in patients with chronic itch conditions . - pubmed
Impressive effect of cisplatin monotherapy on a patient with heavily pretreated triple - negative breast cancer with poor performance . - pubmed
The present case report documents the successful use of cisplatin monotherapy to manage a heavily pretreated TNBC patient showing poor response to therapy . - pubmed
After three cycles of cisplatin treatment , the patient 's metastatic lesions dramatically improved without any major toxicity , and she completed 17 cycles with good response . - pubmed
This case study indicates that patients with heavily pretreated TNBC can potentially achieve a good response to cisplatin monotherapy . - pubmed
Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus ( SARS - CoV-2 ) . - pubmed
Here , we use observations of reported infection within China , in conjunction with mobility data , a networked dynamic metapopulation model , and Bayesian inference , to infer critical epidemiological characteristics associated with SARS - CoV-2 , including the fraction of undocumented infections and their contagiousness . - pubmed
Crowd management today needs to minimise the chances of occurrence of stampedes , fires and other disasters and also to deal with the ongoing threat of terrorism and outbreak of communicable diseases like EBOLA , HIV Aids , Swine Influenza H1N1 , H1N2 , various strands of flu , Severe Acute Respiratory Syndrome ( SARS ) and Middle Eastern Respiratory Syndrome ( MERS ) . - pubmed
Combined Microscopic and Metabolomic Approach to Characterize the Skeletal Muscle Fiber of the Ts65Dn Mouse , A Model of Down Syndrome . - pubmed
In this study , we used a combined methodological approach involving light and electron microscopy , as well as nuclear magnetic resonance spectroscopy metabolomics , to investigate morphology and composition of the quadriceps muscles in the Ts65Dn mouse , a model of DS , to identify structural and/or functional trisomy - associated alterations . - pubmed
Finally , our previous study highlights the mechanisms by which the transition from AKI to CKD does not occur in female rats commonly as it does in male rats . - pubmed
BACKGROUND : Control of bleeding during laparoscopic liver resection ( LLR ) is important for patient safety . - pubmed
shawi ES-62 produced ex vivo was functional and protective in a murine model of arthritis . - pubmed
Endotracheal Intubation in Patients With COVID-19 Infection : Expert Panel - Based Consensus Recommendations . - pubmed
To study the behavior of micrometastases - how they resist initial treatments and then awaken from a dormant state - we utilize the Legacy LiverChip , an all - human ex vivo hepatic microphysiological system . - pubmed
The functional liver bioreactor , comprising hepatocytes and non - parenchymal cells in a 3D microperfused culture format , mimics the dormant - emergent metastatic progression observed in human patients : ( a ) a subpopulation of cancer cells spontaneously enter dormancy , ( b ) cycling cells are eliminated by standard chemotherapies , while quiescent dormant cells remain , and ( c ) chemoresistant dormant cells can be stimulated to emerge . - pubmed
-- Carcinine had a vasodepressive action upon Vertebrates . - pubmed
High frequency of aberrant expression of Moloney murine leukemia virus in clonal infections . - pubmed
Clones of cells were isolated from single virus - single cell infections of NIH / 3T3 cells with Moloney murine leukemia virus . - pubmed
A variety of defective clones were also isolated following infection of rat cells with Moloney virus . - pubmed
The ratio of tumor uptake to fat tissue uptake was correlated with the age of the patient , menopausal status , presence of axillary metastases at time of mastectomy , and the response to endocrine therapy if metastases were presented . - pubmed
There was no correlation between a higher uptake of estradiol by the tumor and age of the patient , menopausal status , or presence of axillary metastases at time of mastectomy . - pubmed
21 patients with hyperlipoproteinaemias of type IIa and IIb were treated with D - thyroxin ( 4 mg / die ) after a placebo phase . - pubmed
Fine structure of meiotic prophase chromosomes and modified synaptonemal complexes in diploid and triploid Rhoeo spathacea . - pubmed
The urinary excretion of nucleosides of ribonucleic acid by patients with advanced cancer . - pubmed
By means of a sensitive and specific method utilizing gas - liquid chromatography , the excretion levels for three nucleosides , degradation minor base products of ribonucleic acid , primarily transfer ribonucleic acid , were determined in 24 - hour urine specimens from over 200 patients with solid tumor malignancies . - pubmed
When compared to normal control values , elevated levels of these compounds were found for patients in each of several tumor types studied . - pubmed
Fourteen patients with radiculomyelitis following acute haemorrhagic conjunctivitis ( AHC ) were seen in Bangkok during October to December 1974 . - pubmed
Most patients developed weakness of extremities 2 weeks after AHC . - pubmed
Six patients received corticosteroid treatment but apart from relief of pain no significant improvement was seen . - pubmed
Motor weakness in 10 patients was less at the end of 2 months , but in 4 it remained unchanged . - pubmed
Most patients with relatively early glaucomatous damage can be satisfactorily managed with topically or orally administered medications . - pubmed
Of 40 patients with thrombotic thrombocytopenic purpura , 17 were treated with plasma exchange , 15 with exchange transfusions , and 6 with both types of therapy . - pubmed
This study supports the hypothesis that plasma exchange has significantly improved the prognosis of patients with thrombotic thrombocytopenic purpura . - pubmed
A 45 - year - old woman was admitted suffering from headache , weight loss , asthenia , pedal edema , and amenorrhea . - pubmed
About half of the patients with central nervous system ( CNS ) leukemia , when submitted systematically to neuroradiological investigations , presented intracerebral solid deposits . - pubmed
Reconstituted vesicular stomatitis virus ( VSV ) envelopes were formed by solubilization of the viral envelope with Triton X-100 followed by removal of detergent by direct addition of SM2 biobeads . - pubmed
Only one patient had worsening of symptoms postoperatively , which was secondary to intracerebral hemorrhage . - pubmed
Furthermore , we show that in one particular region of the optic pathway that the retinal ganglion cell axons avoid in normal animals ( i.e. - pubmed
A 25 - year - old man with juvenile onset diabetes presented with rhinoorbital mucormycosis . - pubmed
The in vivo murine mutation assay should be a useful system for genotoxicity testing and may be of particular value in establishing risk estimates for human populations exposed to genotoxins . - pubmed
An associated patent ductus arteriosus was present in a total of 81 patients . - pubmed
A review was made of the records of 24 consecutive trauma patients ( aged 55 - 94 years ) who had under gone radiographic examinations and a positive bone image of the femur or pelvis . - pubmed
[ State of the cerebral hemodynamics in ischemic stroke patients with hypertension ] . - pubmed
[ Significance of the volume of circulating blood and its components for assessing the state of patients with uterine fibromyoma at the stage of surgical treatment ] . - pubmed
Further studies on the effect of a transplanted methylcholanthrene - induced fibrosarcoma on humoral immunity in CBA mice . - pubmed
[ Agreement between the bacteriological characters of certain strains of the gallinarum - pullorum group of Salmonella and their sensitivity spectrum to bacteriophages obtained beginning with lysogenous strains of the same group ] . - pubmed
Fasciola hepatica infection in cattle . - pubmed
[ Detection of diabetes mellitus in patients with myocardial infarct ] . - pubmed
[ A paratyphoid B infection of human origin as a cause of abortion in a cow ] . - pubmed
17 patients with moderate to severe Raynaud ' s phenomenon were entered into a 6 week randomised double - blind crossover study to compare the efficacy of nifedipine with that of placebo . - pubmed
12 of the patients regarded nifedipine as effective in reducing the frequency and severity of Raynaud ' s phenomenon . - pubmed
Pharmacologic management of glaucoma in the dog . - pubmed
It elicits vocalization in palpated rats and ataxia in dogs . - pubmed
induced significant osteoporosis in C3H / St ( Ha ) female mice after 3 months of treatment . - pubmed
Vulvovaginitis caused by Yersinia enterocolitica . - pubmed
The animals of the main series ( 7 dogs ) with a veno - venous connection of the membrane oxygenator ( MO ) tolerated hypoxia quite well for 2 hours . - pubmed
One hundred children with cancer and bacterial sepsis were observed for one month after completion of antibiotic treatment for subsequent episodes of infection . - pubmed
Of the 26 neutropenic patients not receiving TMP - SMZ 23 ( 88 % ) had episodes of infection , whereas 4 ( 36 % ) of the 11 given the drug had recurrent or re - infection episodes ( P = less than 0.001 ) . - pubmed
A difference of similar significance was observed in the non - neutropenic patients . - pubmed
Infections in children in relapse of their malignancy were twice as frequent in those not receiving the drug as in those who received it ( P = less than 0.02 , greater than 0.01 ) . - pubmed
This study shows that the administration of TMP -- SMZ after bacterial sepsis reduces the number of infectious episodes in neutropenic and non - neutropenic patients , with the exception of the non - neutropenic patient in remission . - pubmed
Production of prostaglandins in homogenates of kidney medullae and cortices of spontaneously hypertensive rats fed menhaden oil . - pubmed
Menhaden oil ( MO ) , whose polyunsaturated fatty acids consist mainly of ( n-3 ) fatty acids , was fed to spontaneously hypertensive rats to determine the effect of ( n-3 ) fatty acid on the in vitro production of prostaglandins produced from arachidonic acid ( 20:4[n-6 ] ) . - pubmed
During a 1 - year period 10 newborns with myelodysplasia were seen . - pubmed
Disulfiram has been shown to decrease the incidence of arrhythmias in rabbits exposed to trichloroethylene . - pubmed
significantly decreased the time spent in arrhythmia compared to control rabbits , 120 - 180 s following intravenous administration of 4 mg / kg barium chloride . - pubmed
The effect of prodectin was examined in 79 patients with coronary disease after a course of treatment , and in 16 normal subjects . - pubmed
Therefore the drug appears to be advisable for patients with coronary disease exposed to increased information inflow which requires greater concentration of their attention in short time . - pubmed
Twenty - seven patients with 28 aseptic nonunions were treated with reamed intramedullary ( IM ) nailing of the tibia and were followed for at least 1 year postoperatively . - pubmed
OBJECTIVE : To address the frequency of side effects of Ritalin therapy in children with attention deficit hyperactivity disorder ( ADHD ) using the Barkeley Side Effects Questionnaire ( BSEQ ) in a clinical setting . - pubmed
PATIENTS : 234 consecutive children aged 5 through 15 years who met the Diagnostic and Statistical Manual of Mental Disorders ( 3rd ed , revised ) criteria for ADHD were enrolled . - pubmed
CONCLUSION : The BSEQ proved to be clinically effective in tracking Ritalin side effects and should be incorporated into the routine evaluation and monitoring of ADHD patients for whom stimulants are prescribed . - pubmed
Labiatae allergy : systemic reactions due to ingestion of oregano and thyme . - pubmed
BACKGROUND : There are no cases described in the medical literature of systemic allergic reactions due to oregano ( Origanum vulgare ) or thyme ( Thymus vulgaris ) . - pubmed
OBJECTIVE : We describe three systemic allergic reactions caused by oregano and thyme in the same patient . - pubmed
Realization of the potential of foodborne substances to reduce the human burden of cancer will only be achieved with better measurement of dietary exposures and funding of multidisciplinary research in this area commensurate with its importance . - pubmed
Typing of nosocomial strains of Serratia marcescens : comparison of restriction enzyme cleaved genomic DNA fragment ( PFGE ) analysis with bacteriocin typing , biochemical profiles and serotyping . - pubmed
Based on the analysis of PFGE patterns against the background of epidemiological data , the number of nosocomically significant strains of S. - pubmed
OBJECTIVES : Determine possible differences in clinical manifestations , laboratory findings and neuroimaging results in tuberculous meningitis patients with and without HIV infection . - pubmed
RESULTS : There were 24 HIV - infected patients and 14 without HIV infection . - pubmed
Age ( median age = 33 years for the HIV group vs. 53 for the non - HIV group ) , sex ratio ( 3 vs. 0.75 ) , and prior history of tuberculosis ( 46 % vs. 43 % ) were similar in both groups . - pubmed
Clinical presentation was similar for headache ( 83 % in HIV group vs. 50 % in non - HIV group ; p = 0.02 ) and confusion ( 54 % vs. 93 % in non - HIV group p = 0.05 ) . - pubmed
Remodeling with neointima formation in the mouse carotid artery after cessation of blood flow . - pubmed
Using a denuding - injury procedure , we recently reported that intimal lesions can be induced in the carotid artery of outbred mice . - pubmed
The technical challenge associated with achieving complete denudation and the relatively small size of the developing lesions prompted us to design the present model of neointima formation and vascular remodeling in the carotid artery of the inbred FVB mouse strain . - pubmed
[ Artificial nutrition of patients with toxic epidermal necrolysis ( Lyell syndrome ) ] . - pubmed
The authors report the case of a 30 - year - old man treated with toxic epidermal necrolysis . - pubmed
The patient was admitted with denudated skin surface similar to second - degree burn that covered 90 per cent of the patient 's body surface . - pubmed
The patient was isolated and treated , receiving sterile wound care , broad spectrum antibiotic and corticosteroid . - pubmed
The early recognition of the disease , the intensive care and nutritional therapy may improve the survival of patients with toxic epidermal necrolysis . - pubmed
Overall , both groups of patients experienced less pain than expected , except on days 3 and 4 . - pubmed
Patients in the metronidazole group had significantly less pain than those in the placebo group on days 5 , 6 , and 7 ( p = 0.004 , p = 0.02 , and p = 0.006 ) . - pubmed
INTERPRETATION : Prophylactic metronidazole in diathermy DCH suppressed secondary pain around days 5 - 7 and increased patient satisfaction and earlier return to work . - pubmed
To qualify water , TMM - I ( integral indication of micro - organisms ) , TMM - C ( coccal indication ) , and TMM - BP ( indication of blue pus Pseudomonas aeroginosa ) will be necessary and sufficient . - pubmed
PATIENTS AND METHODS : Between January 1995 and December 1997 , 60 patients with pituitary adenomas were operated on at Okayama University Hospital . - pubmed
The extradural temporopolar approach was used for 5 patients who had a giant pituitary adenoma invading the cavernous sinus and parasellar regions . - pubmed
The 5 patients were women aged from 32 to 62 years and presented with a visual dysfunction . - pubmed
Four patients had hormonally non - functioning pituitary adenomas and one had a growth - hormone secreting pituitary adenoma . - pubmed
In this study 41 new HIV-1 strains , representing the majority of the described envelope subtypes of HIV-1 ( A to H ) , were genetically characterized in the nef region . - pubmed
In the 20 patients who had both nebulisers , the mean percentages of stomach deposition for the Ventstream and Optimist nebulisers were 11.8 % and 1.6 % , respectively . - pubmed
40 epileptic 5 - 12 year - old children as well as 9 healthy children ( a control group ) were examined . - pubmed
To determine whether the Neo gene also confers resistance to vertebrate ototoxicity , the sensitivity of cochlear hair cells to neomycin was evaluated in mice with a targeted insertion of Neo . - pubmed
Organotypic cultures of the organ of Corti , isolated from neonatal wild - type mice and two strains of mice carrying the Neo gene , were cultured for 72 h in the absence ( controls ) or in the presence of 200 microM neomycin . - pubmed
Establishment and characterization of human pancreatic carcinoma lines with a high metastatic potential in the liver of nude mice . - pubmed
To investigate of human pancreatic cancer metastasis to the liver , a pancreatic carcinoma line , HPC-3 , was injected into the spleens of nude mice . - pubmed
The mice were observed to have liver metastasis in 6 of 6 ( 100 % ) cases injected with HPC-3H4 , whereas the rate was 0 % at 3 weeks after the intrasplenic injection of HPC-3 . - pubmed
This approach can be used in conjunction with existing information to assist clinicians in the management of patients with acute low back pain . - pubmed
In a retrospective study , all patients who underwent surgery for abdominal aortic aneurysm were reevaluated by preoperative diagnostic and therapeutic interventions for cardiovascular disease . - pubmed
Of 603 patients operated upon for abdominal aortic aneurysm between 1980 and 1996 , 449 had surgery on an elective basis and 154 as an emergency . - pubmed
Preoperative diagnostic studies for coronary artery disease were performed on elective patients and were positive in 76.8 % ( 1980 - 1989 , 76.1 % , 1990 - 1996 , 77.5 % ) . - pubmed
Let us present a case of recurrent paranoid psychotic episodes in a patient with a history of abuse of & lt;<ecstasy>> ; ( MDMA : 3 , 4 - methylenedioxymethamphetamine ) , that persisted after a long withdrawal time , that , in our opinion , after an exhaustive differential diagnosis , may be attributed to that consumption . - pubmed
The permanent changes in the evoked response audiograms and sensory cell populations were the same in Groups 1 , 2 and 3 that were exposed to the traumatic noise , regardless of whether or not the animals were ever subjected to the toughening noise or whether the toughening noise preceded or followed the traumatic noise . - pubmed
The dose - effect relationship for morphine and vomiting after day - stay tonsillectomy in children . - pubmed
A dose - response curve for intravenous morphine and vomiting was investigated in children having day - stay tonsillectomy . - pubmed
Fifty - five of these 164 children vomited and 20 children required an overnight stay in hospital because of vomiting . - pubmed
Our data suggests that lower doses of morphine are associated with a decreased incidence of emesis after tonsillectomy in children . - pubmed
METHODS : Patients presenting with musculoskeletal pain requiring NSAID treatment and without previous exposure to NSAID or pre - existing ulcers were recruited . - pubmed
Patients with non - ulcer dyspepsia and H. - pubmed
Excluding the 50 women whose babies were delivered for fetal distress ( leaving 1228 women for analysis ) , the epidural rate was 93 % , range 81 - 98 % , and the cesarean delivery rate was 14 % , range 8 - 34 % . - pubmed
Logistic regression analyses revealed that ( odds ratio , 95 % confidence interval ) patient age ( 1.7 , 1.2 - 2.4 ) , birth weight ( 1.001 , 1.001 - 1.002 ) , induction of labor ( 1.9 , 1.3 - 2.7 ) , non - Caucasian ( 1.9 , 1.2 - 2.9 ) and the obstetrician group , ( P=0.002 ) , were independently associated with the risk of cesarean delivery , but epidural analgesia was not ( 1.6 , 0.7 - 3.6 ) . - pubmed
Alzheimer ' s disease ( AD ) is the most common human neurodegenerative disorder characterized by the progressive deterioration of cognition and memory in association with the presence of senile plaques , neurofibrillary tangles , and massive loss of neurons . - pubmed
It is now generally accepted that massive neuronal death due to apoptosis is a commmon characteristic in the brains of patients suffering from neurodegenerative diseases , and apoptotic cell death has been found in neurons and glial cells in AD . - pubmed
Patients with profound sensorineural hearing loss due to mtDNA defects should be considered as candidates for cochlear implantation when they no longer benefit from conventional hearing aids . - pubmed
We report two children , sisters , both with severe , recurrent hemorrhagic complications from factor VII deficiency , successfully treated with orthotopic liver transplantation . - pubmed
Among rats in the 4 TPN groups surviving 7 days , there were no significant differences in body weight change ( minus 3 - 4 % ) , spleen or lung weight , extent of liver regeneration ( 61 - 66 % ) . - pubmed
Among rats surviving for 7 days , body weight change ( minus 3 - 5 % ) , liver regeneration ( 67 - 70 % ) , and liver tests were similar in both groups . - pubmed
Representation of pain and somatic sensation in the human insula : a study of responses to direct electrical cortical stimulation . - pubmed
We studied painful and non - painful somaesthetic sensations elicited by direct electrical stimulations of the insular cortex performed in 43 patients with drug refractory temporal lobe epilepsy , using stereotactically implanted depth electrodes . - pubmed
In humans , both a posterior and an anterior pain - related cortical area have been described within the insular cortex using functional imaging . - pubmed
The effect of 450 mg / day propafenone for two weeks on premature ventricular contractions ( PVCs ) was studied in combination with an assessment of heart rate ( HR ) dependency of PVCs using Holter ECG monitoring in patients with more than 720 PVCs per day . - pubmed
Human infection with the sheep liver fluke Fasciola hepatica is a global zoonosis that usually parallels the prevalence of infection in sheep and other ruminants . - pubmed
Therefore , we report a case of acute human fascioliasis and review the pathogenesis , diagnosis , and treatment of this disease in a recently arrived immigrant . - pubmed
The risk factors affecting the outcome in 50 children with tuberculous meningitis were evaluated over a period of 20 months . - pubmed
Younger age , tonic posturing , papilloedema , focal neurological deficit and stage at presentation were found to affect adversely the prognosis independently in children with tuberculous meningitis . - pubmed
The presence of glomerular pathologic findings attributable to hypercalcemia has been observed in only a few patients and therefore has been considered an unusual finding . - pubmed
In the current study , calcium deposition within glomeruli was investigated in 2 patients with extreme elevations in serum calcium levels and hypercalcemic nephropathy . - pubmed
The study material consisted of a renal biopsy specimen from a 31 - year - old woman ( patient 1 ) who had T - cell lymphoma / leukemia and a serum calcium level of 20.2 mg / dL ( 5.0 mmol / L ) and autopsy kidney specimens from a 19 - year - old woman ( patient 2 ) who was being evaluated for primary hyperparathyroidism and a calcium level of 18.4 mg / dL ( 4.6 mmol / L ) . - pubmed
Glomerular calcinosis may also be recognized as an additional cause of segmental glomerulosclerosis and nephrotic range proteinuria in patients with extremely high levels of serum calcium . - pubmed
Effect of simulated field deposits of gamma - BHC and dieldrin on suceptible , hybrid and resistant strains of Anopheles gambiae Giles . - pubmed
Variability of incidence and clinical manifestation of mouse hereditary muscular dystrophy on heterogeneous genetic backgrounds . - pubmed
2,3,7,8 - Tetrachlorodibenzo - p - dioxin ( TCDD ) is a widespread environmental contaminant , that has been linked with a variety of deleterious effects on human health , including increased cancer rates and reproductive anomalies . - pubmed
Patients with isolated deep venous thrombosis or deep venous thrombosis with concomitant pulmonary embolism seemed to have similar benefit . - pubmed
Antiestrogen tamoxifen seems useful in HCC patients . - pubmed
A pilot study was performed to evaluate the effect of all - trans retinoic acid associated with tamoxifen and vitamin E on patients with advanced HCC . - pubmed
PATIENTS AND METHODS : Fifteen consecutive patients with advanced HCC were included in the study . - pubmed
Pain and asthenia were improved in the majority of patients . - pubmed
CONCLUSION : A combination therapy of all - trans retinoic acid , tamoxifen and vitamin E increases the survival rate and ameliorates the clinical outcome in patients with inoperable HCC . - pubmed
108 ambulatory patients with clinical signs of conjunctivitis and blepharoconjunctivitis were enrolled in the study . - pubmed
The adjustable suture procedures performed during a 5 - year period , on non - thyroid eye disease patients , were matched to non - adjustable cases according to the type and aetiology of strabismus and the magnitude of deviation . - pubmed
The authors conclude that there is currently insufficient evidence that patients , without thyroid eye disease , benefit from the longer and potentially uncomfortable procedure of adjustable suture strabismus surgery to support its rapidly growing use and that a prospective randomised controlled trial is indicated . - pubmed
PURPOSE OF REVIEW : The purpose of this paper is to review current animal models that may be useful for studying cancer associated with human immunodeficiency virus infection . - pubmed
RECENT FINDINGS : Several animal models , primarily using mice and monkeys , have been developed that recapitulate aspects of the pathology of various malignancies in human acquired immune deficiency syndrome . - pubmed
The incidence of DVT from positive radionuclide venography was 24 % ( 16/67 patients ) and PE was 12 % ( 8/67 patients ) . - pubmed
Between 1999 and 2001 , 89 patients with peripheral arterial disease categorized as TASC C ( n=37 ) and D ( n=52 ) underwent percutaneous interventional reconstruction and stent implantation . - pubmed
OBJECTIVE : To describe the unmasking of pheochromocytoma in a patient treated with amisulpride and tiapride . - pubmed
CASE SUMMARY : A 42 - year - old white man developed acute hypertension with severe headache and vomiting 2 hours after the first doses of amisulpride 100 mg and tiapride 100 mg . - pubmed
CONCLUSIONS : As of March 24 , 2005 , this is the first reported case of amisulpride- and tiapride - induced hypertensive crisis in a patient with pheochromocytoma . - pubmed
Infarction of the right hemisphere in a patient with antiphospholipid antibody syndrome . - pubmed
Hemicraniectomy as a surgical treatment for intracranial pressure following large ischemic lesions is widely practiced in selected patients . - pubmed
Postoperative cauda equina syndrome in patients undergoing single - level lumbar microdiscectomy . - pubmed
In this paper , the authors report two cases of postoperative cauda equina syndrome in patients undergoing single - level de novo lumbar microdiscectomy in which intraoperative electrophysiological monitoring was used . - pubmed
Postoperative magnetic resonance images obtained in both patients , and a lumbar myelogram obtained in the second one revealed no signs of conus medullaris or nerve root compression . - pubmed
The authors ' findings support the proposition that intraoperative SSEP monitoring may be useful in predicting the development of cauda equina syndrome in patients undergoing lumbar microdiscectomy . - pubmed
Disappearance of HCV after cessation of immunosuppression in a patient with ulcerative colitis and renal transplantation . - pubmed
PATIENTS AND METHODS : Disseminated epithelial prostate cancer cells were isolated from bone marrow aspirates from 69 men with localized prostate cancer before RP , by magnetic column - chromatography enrichment , followed by isolation of fluorescently labelled epithelial cells by micropipetting . - pubmed
We report the case of a young man with a recurrent idiopathic priapism , successfully treated with methoxamine intracarvenosal self - injections . - pubmed
OBJECTIVE : The goals of the study were to : 1 ) determine the acceptability of STI testing among individuals seeking services at shelters in 2 midsized southeastern cities ; 2 ) evaluate the prevalence of chlamydia , gonorrhea , syphilis , and HIV among these individuals ; and 3 ) assess the proportion that subsequently learned their test results and received timely and appropriate treatment if warranted . - pubmed
The rate of CT in city B was significantly higher than city A ( 15.0 % vs. 6.4 % , P = 0.02 ) ; however , similar rates were found for GC ( 5.0 % vs. 3.2 % ) , primary and secondary syphilis ( 0.08 % vs. 1.4 % ) , and HIV ( 0.07 % vs. 0.06 % ) . - pubmed
CONCLUSION : We found that shelter clients were receptive to STI testing , even for HIV , with most positive cases notified and successfully treated . - pubmed
First reported case of dialysis - related peritonitis due to Escherichia vulneris . - pubmed
This is the first reported case of peritonitis due to E. - pubmed
Our patient is a 62 - year - old woman with longstanding systemic arterial hypertension and angina pectoris . - pubmed
An ongoing clinical trial is designed to determine whether NO - ASA can inhibit early stages of colon carcinogenesis in subjects at risk for colon cancer . - pubmed
We assessed left ventricular ( LV ) systolic function with DTI in 45 human immunodeficiency virus ( HIV )- infected patients without any heart - related symptoms and in 30 healthy control subjects . - pubmed
Thromboprophylaxis for patients at high risk of VTE . - pubmed
The cell death in male Wister rats were studied from 6 h until 4 days after global cerebral ischemia induced by transient 2 - vessel carotid occlusion with hypotension for 15 min . - pubmed
Modulation of experimental osteoporosis in rats by the antioxidant beverage effective microorganism - X ( EM - X ) . - pubmed
The levels of serum estradiol ( E(2 ) ) and the bone density of the middle and epiphysis of femurs were assessed in order to determine the effect of EM - X on osteoporosis in ovariectomized rat ( an animal model of postmenopausal osteoporosis ) . - pubmed
Patients determined to have prostate adenocarcinoma underwent radical retropubic prostatectomy . - pubmed
Myelin contains many axonal outgrowth inhibitory components which contribute to regeneration failure after neuronal injury in the mammalian central nervous system ( CNS ) . - pubmed
Fifty - two patients with MS were enrolled in the study . - pubmed
We found that 22 patients had primary progressive , 18 patients had relapsing - remitting and 12 patients had secondary progressive MS . - pubmed
Detrusor sphincter dyssynergia was found in 25 % of patients , and detrusor hyporeflexia was detected in 6 % . - pubmed
Decrease in viral load at weeks 12 and 24 in patients with chronic hepatitis B treated with lamivudine or adefovir predicts virological response at week 48 . - pubmed
CONCLUSION : The decrease in viral DNA at weeks 12 and 24 can predict VR at one year in patients with chronic hepatitis B treated with LAM or ADF . - pubmed
GABA concentration in schizophrenia patients and the effects of antipsychotic medication : a proton magnetic resonance spectroscopy study . - pubmed
Among the right handed schizophrenia patients , the GABA concentration in the ltBG was significantly higher in patients taking typical antipsychotics ( 1.25+/-0.24 mmol / l ) than in those taking atypical antipsychotics ( 1.03+/-0.24 mmol / l , p=0.026 ) . - pubmed
It is possible that medication effects conceal inherent differences in GABA concentrations between schizophrenia patients and healthy controls . - pubmed
Pump - treated type 1 diabetes subjects were randomized to one bolus waveform for one full day of three meals and then crossed over to the other bolus waveforms . - pubmed
A rational use of glucocorticoids in patients with early arthritis has a minimal impact on bone mass . - pubmed
INTRODUCTION : Glucocorticoid ( GC)-induced osteoporosis is a frequent complication in patients with rheumatoid arthritis . - pubmed
METHODS : Data from 116 patients in our early arthritis register were analyzed ( 90 women ; median age , 52.5 years , interquartile range ( IQR , 38.5 - 66 ) ; 6 - month median disease duration at entry ( IQR , 4 - 9 ) ) . - pubmed
RESULTS : Of the patients with early arthritis studied , 67 % received GCs during the 2 - year follow - up . - pubmed
CONCLUSIONS : The frequent use of GCs as a " bridge therapy " in patients with early arthritis does not seem to be associated with relevant loss of bone mass . - pubmed
Health care - associated and community - associated methicillin - resistant Staphylococcus aureus infections : A comparison of definitions . - pubmed
MATERIAL AND METHODS : There were studied 459 heart failure patients admitted in the Cardiology Department of a general hospital in Cluj - Napoca , Romania . - pubmed
Goal - oriented cognitive rehabilitation for people with early - stage Alzheimer disease : a single - blind randomized controlled trial of clinical efficacy . - pubmed
Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection . - pubmed
This included 573 renal ablation procedures performed in 533 patients to treat 633 tumors . - pubmed
Reverse genetics viruses for influenza vaccine production usually utilize the internal genes of the egg - adapted A / Puerto Rico / 8 / 34 ( PR8 ) strain . - pubmed
Influence of gender on long - term mortality in patients presenting with non - ST - elevation acute coronary syndromes undergoing percutaneous coronary intervention . - pubmed
Deep sequencing detected a potential bioterrorism agent , Francisella tularensis , in a human abscess sample ( Iwaki-08 ) of unknown etiology . - pubmed
The in vivo effects of both Comp.1 and Comp.2 were evaluated on hippocampal neurogenesis in olfactory bulbectomized ( OBX ) mice , an experimental depression and dementia animal model . - pubmed
OBJECTIVE : To analyze the outcome of patients after surgical or nonoperative treatment of Hadley type IIA odontoid fractures . - pubmed
METHODS : We analyzed the records of 46 patients at an average of 64 years of age at the time of injury . - pubmed
Infection - associated nuclear degeneration in the rice blast fungus Magnaporthe oryzae requires non - selective macro - autophagy . - pubmed
BACKGROUND : The rice blast fungus Magnaporthe oryzae elaborates a specialized infection structure called an appressorium to breach the rice leaf surface and gain access to plant tissue . - pubmed
AIMS : To describe the longitudinal course of thrombocytopenia and risks for bleeding in veteran patients with non - hepatitis C - related CLD . - pubmed
CONCLUSIONS : Among veteran patients with non - hepatitis C - related CLD , baseline platelet counts of 50,000 to 100,000 / mul increased subsequent risks for both incident severe thrombocytopenia and major bleeding events . - pubmed
Results showed that , in a dose - dependent manner , KCN1 inhibited cell growth and induced cell cycle arrest in human pancreatic cancer cells in vitro , and showed in vivo anticancer efficacy in mice bearing Panc-1 or Mia Paca-2 tumor xenografts . - pubmed
This study aimed to characterize in vivo the carotid arterial intima - media thickness ( IMT ) and mechanical properties in women with pre - eclampsia by employing a radiofrequency ultrasound technique . - pubmed
METHODS : We included 22 late - onset pre - eclamptic pregnant women and 28 normotensive pregnant women who were matched for age ( 29 + - 6 vs. 27 + - 3 , P=0.09 ) and gestational age ( 36.0 + - 3.2 vs. 35.8 + - 2.4 weeks , P=0.802 ) . - pubmed
The pre - eclamptic women had a significantly higher arterial pressure than did the normotensive women ( P<0.0001 ) . - pubmed
At follow - up examination 18 months after parturition , measurements were repeated in 10 of the pre - eclamptic women and 11 of the normotensive women . - pubmed
Effects of the serotonergic agonist mCPP on male rats in the quinpirole sensitization model of obsessive - compulsive disorder ( OCD ) . - pubmed
RATIONALE : The serotonergic agonist , meta - chlorophenylpiperazine ( mCPP ) , produces inconsistent effects on obsessive - compulsive disorder ( OCD ) symptoms , perhaps because clinical studies have not utilized a homogenous OCD subgroup of patients . - pubmed
OBJECTIVES : This study aimed to evaluate mCPP effects on functional components of compulsive checking , using the quinpirole sensitization rat model of OCD . - pubmed
METHODS : In study 1 , the effects of mCPP were evaluated in quinpirole rats with compulsive checking . - pubmed
In study 2 , mCPP ( 0 , 0.3125 , 0.625 , and 1.25 mg / kg ) was administered repeatedly to naive rats and induction of compulsive checking evaluated . - pubmed
In naive rats , mCPP did not induce compulsive behavior , but the highest dose reduced vigor of checking performance compared to saline controls . - pubmed
Lung and intestine : a specific link in an ulcerative colitis rat model . - pubmed
To investigate the link and mechanisms between intestine and lung in the ulcerative colitis ( UC ) rat model . - pubmed
Our study is the first to demonstrate the close association between the large intestine and lung in the immune - TNBS - ethanol - induced UC rat model . - pubmed
OBJECTIVE : To analyze the clinical features , diagnosis and treatment of thrombotic thrombocytopenic purpura ( TTP ) in patients with systemic lupus erythematosus ( SLE ) . - pubmed
METHODS : Clinical manifestations , laboratory findings , diagnosis , treatment and prognosis of 14 SLE patients with TTP were retrospectively analyzed . - pubmed
RESULT : Of the 14 patients diagnosed with SLE and TTP , 4 were men and 10 were women . - pubmed
In five patients , the onset of SLE preceded TTP , and in nine patients SLE and TTP occurred simultaneously . - pubmed
All the 14 patients had thrombocytopenia and hemolytic anemia , 12 had fever , 11 had neurologic abnormalities , and 11 had renal dysfunction . - pubmed
The renal damage in patients of co - existing diseases is more serious than those with TTP alone or SLE alone . - pubmed
Early diagnosis and prompt treatment with plasma exchange and steroids may improve the prognosis in SLE patients with TTP . - pubmed
, peanut ) , insect stings , and several medications . - pubmed
Histologic study of a human immature permanent premolar with chronic apical abscess after revascularization / revitalization . - pubmed
CONCLUSIONS : The presence of a dedicated osteoporosis health professional coordinating a targeted intervention for outpatients with low trauma non - hip fracture improves investigation and management of osteoporosis , resulting in the potential for future fracture prevention . - pubmed
Cephalic arch stenosis in dialysis patients : review of clinical relevance , anatomy , current theories on etiology and management . - pubmed
PARTICIPANTS : Patients with chronic pain of at least 6 months , and age 18 years or older . - pubmed
BACKGROUND : Surgery followed by radiotherapy ( RT ) is indicated for patients with high - risk oral cavity cancer ( OCC ) . - pubmed
Thirty - two patients ( 78 % ) remained disease - free , 6 ( 15 % ) developed locoregional recurrence ( 4 in - field , 1 marginal , and 1 out - field ) and 4 ( 10 % ) developed distant metastasis . - pubmed
Vancomycin - associated acute kidney injury in pediatric cardiac intensive care patients . - pubmed
OBJECTIVE : Acute kidney injury ( AKI ) is a significant source of morbidity among critically ill pediatric patients , including those that have undergone cardiac surgery . - pubmed
Vancomycin may contribute to AKI in pediatric patients admitted to a cardiac intensive care unit . - pubmed
Patient demographic and disease state variables , vancomycin therapy variables , and use of other nephrotoxic medications were collected . - pubmed
Patients who developed vAKI were matched with three patients who did not develop vAKI , and conditional logistic regression was used to determine independent risk factors for vAKI . - pubmed
Vancomycin - associated AKI occurred in 30 patients ( 7.2 % ) , which resulted in a total of 120 patients ( 30 cases ; 90 controls ) . - pubmed
BACKGROUND : Less than two percent of the human genome is protein coding , yet that small fraction harbours the majority of known disease causing mutations . - pubmed
Visceral leishmaniasis ( VL ) , also known as kala - azar , is a disseminated protozoan infection caused by Leishmania donovani complex . - pubmed
In conclusion , the findings of this study supports the use of PCR on archive cytological preparation stained slides for the diagnosis of canine visceral leishmaniasis , emphasizing the higher sensitivity of this technique when compared to direct microscopic examination and mostly the use of the suspect status for the cytology samples that presents the previously mentioned particularities with focus on detecting the oligosymptomatic or assymptomatic dogs in endemic areas functioning as potential reservoirs for this disease . - pubmed
Field trial of Xanthomonas wilt disease - resistant bananas in East Africa . - pubmed
BACKGROUND : Patients living with HIV ( PLHIV ) are increasingly being affected by cancer . - pubmed
However , data evaluating the long - term impact of cancer treatment on HIV course are sparse . - pubmed
Adult PLHIV treated for haematological or solid malignancies were included and compared ( 1:1 ) with suitably matched ( cancer - free ) controls . - pubmed
RESULTS : One - hundred - and - ten patients with cancer and 110 controls were followed for a median of 4.4 years . - pubmed
Misregulation of autophagy is likely involved in numerous human pathologies including aging , cancer , infections and neurodegeneration , so its biomedical relevance explains the still growing interest in this field . - pubmed
Ability of obstacle crossing is not associated with falls in independent ambulatory patients with spinal cord injury . - pubmed
OBJECTIVE : To investigate the relationship between ability of obstacle crossing and falls in independent ambulatory participants with spinal cord injury ( SCI ) . - pubmed
METHODS : Ninety - four participants were evaluated for their SCI characteristics , ability of walking over small obstacles and functional ability relating to dynamic balance control , lower - extremity motor strength ( LEMS ) and walking ability . - pubmed
The CAD genotypes had no effect on the relative content of cellulose and lignin in stalks ofdiploid wheat and insignificantly influenced the ratio of H : G : S units in the lignin structure , as well as some components of extractives . - pubmed
OBJECTIVE : To investigate the associations between obesity and any significant improvements in glycemic control , blood pressure , and lipid targets in Chinese patients with concomitant type 2 diabetes mellitus ( T2DM ) and hypertension . - pubmed
METHODS AND RESULTS : A total of 3041 dyslipidemia patients with an average age of 65.7 + - 10.53 years and comorbid conditions of T2DM and hypertension from the DYSlipidemia International Study ( DYSIS ) - China were included in the present subgroup analysis . - pubmed
AREAS COVERED : This article reviews the chemical structure , mechanisms of action , pharmacodynamic and pharmacokinetic properties , as well as clinical applications of small molecules in the treatment of elderly patients with B - cell hematological malignancies . - pubmed
Pharmacokinetic profiles of these agents as well as dosage used and adverse events in patients with lymphoid malignancies have been established . - pubmed
Some of these inhibitors satisfy therapeutic modalities as suitable for the elderly patients , including those with chronic lymphocytic leukemia and non - Hodgkin ' s lymphoma . - pubmed
METHODS : The SOLVE study was a 24 - week observational study on the initiation of IDet OD in T2DM patients with uncontrolled hyperglycemia on diet , exercise , and one or more OADs . - pubmed
Body weight tended to decrease in patients from all groups , however , only that in the 2 - OAD group reached statistically significance . - pubmed
CONCLUSION : Initiation of IDet OD was effective and well - tolerated in Chinese patients with T2DM whose glycemia was poorly controlled on OADs irrespective of the number of OADs taken before . - pubmed
Assessment of operative treatment of patients with tertiary hyperparathyroidism after kidney transplantation . - pubmed
INTRODUCTION : The purpose of the study was to assess the results of operative treatment of patients with tertiary hyperparathyroidism ( tHPT ) after kidney transplantation . - pubmed
MATERIAL AND METHODS : The study included 30 patients in whom kidney transplantation was performed between 2006 and 2013 , and in whom parathyroidectomy had to be performed at a later time because of tHPT . - pubmed
Histopathological examination showed one parathyroid adenoma in six ( 20 % ) patients , and one parathyroid adenoma and hyperplasia of the remaining glands in one ( 3.3 % ) patient . - pubmed
Five ( 16.7 % ) patients had hyperplasia of two parathyroid glands whereas no changes were observed in two patients . - pubmed
On the other hand , hyperplasia of all glands was noted in 18 ( 60 % ) patients . - pubmed
CONCLUSIONS : Surgical resection of parathyroid glands is a management of choice in patients after kidney transplantation accompanied by hypercalcaemia lasting longer than one year . - pubmed
Resection of 3 3/4 parathyroid glands because of hyperplasia in patients with hyperparathyroidism after kidney transplantation enables restoration of normal calcium metabolism . - pubmed
OBJECTIVES : To analyze the acute effects of isolated and simultaneous application of whole - body vibration ( WBV ) and electromyostimulation ( ES ) on popliteal artery blood velocity ( BV ) and skin temperature ( ST ) of the calf in subjects with spinal cord injury ( SCI ) . - pubmed
METHODS : Ten subjects with SCI were assessed in five different sessions . - pubmed
This study provides an efficient therapeutic methodology to improve peripheral arterial properties , which is pivotal in SCI patient 's rehabilitation . - pubmed
PURPOSE OF THE STUDY : We present the results of a prospective study of patients with symptomatic partial ACL tears comparing the pre - operative findings with the clinical results at two years after anterior cruciate ligament ( ACL ) augmentation . - pubmed
Graft failure was reported in one patient ( 5.6 % ) and 14 subjects ( 77.8 % ) reported return to pre - injury sports activities . - pubmed
Three recent clinical trials on the pharmacologic treatment of idiopathic pulmonary fibrosis ( IPF ) mark a new chapter in the management of patients suffering from this very severe fibrotic lung disease . - pubmed
A better understanding of the molecular mechanisms of IPF as well as relevant preclinical tests including animal models and in vitro experiments on human lung cells are needed to promote the development of therapeutic drugs . - pubmed
KEY FINDINGS : These products have relevant cytotoxicity at a 10 muM concentration and it was also demonstrated for the first time that H. - pubmed
Detection of Helicobacter felis in a cat with gastric disease in laboratory animal facility . - pubmed
A 3 - month - old male cat in the animal facility was presented for investigation of anorexia and occasional vomiting . - pubmed
felis - induced gastroenteric disease in cat and may provide a valuable data on the study of feline Helicobacter infection . - pubmed
MATERIAL AND METHOD : A total of 390 patients who underwent surgery to treat anterior shoulder instability between March 2013 and June 2014 were included and divided into three groups depending on whether they were managed using open surgery with screw fixation , arthroscopy with screw fixation , or arthroscopy with endobutton fixation . - pubmed
Here we describe a mouse model of DIPG in which H3K27 M potentiates tumorigenesis . - pubmed
The most interesting advances have been incorporating orthodontic procedures in conjunction with myofunctional therapy in prepubertal children , raising the possibility of OSA prevention by initiating treatment early in life . - pubmed
Promising Effects of Neurorestorative Diets on Motor , Cognitive , and Gastrointestinal Dysfunction after Symptom Development in a Mouse Model of Parkinson ' s Disease . - pubmed
This is the first study demonstrating beneficial effects of specific dietary interventions , given after full development of symptoms , on a broad spectrum of motor and non - motor symptoms in a mouse model for PD . - pubmed
However , many patients with RA fail to respond to this or other biologics , and some patients may suffer unexpected aggravation of arthritic inflammation or other autoimmune effects . - pubmed
Molecular epidemiology of Escherichia coli sequence type 131 and its H30 / H30 - Rx subclones recovered from extra - intestinal infections : first report of OXA-48 producing ST131 clone from Iran . - pubmed
Multidrug - resistant ( MDR ) O25b - ST131 clone of Escherichia coli is well established as a significant cause of extra - intestinal infections worldwide . - pubmed
The prevalence of ST131 was 29.8 % among phylogroups B2 , D , and F of E.coli isolates recovered from extra - intestinal infections . - pubmed
PURPOSES : To establish the in silico ocular pharmacokinetic modeling for eye drops , and to simulate the dose regimen for FK962 in human choroid / retinal diseases . - pubmed
Neurite elongation by FK962 was measured in cultured rat retinal ganglion cells . - pubmed
PURPOSE : The case of a patient who experienced bone marrow edema and pain in both feet and a compression fracture of one heel bone after several months of everolimus use is reported . - pubmed
The patient was referred for orthopedic evaluation , which resulted in diagnosis of bone marrow edema and a compression fracture of the calcaneus on the basis of magnetic resonance imaging results . - pubmed
The case was discussed with a clinical pharmacist , and after an in - depth analysis to rule out potential alternative causes for the patient 's edema and pain , everolimus was discontinued . - pubmed
CONCLUSION : Bone marrow edema developed and a fracture occurred in a patient taking everolimus for a metastatic pNET , with complete resolution of lower extremity swelling and pain within 2 weeks of everolimus discontinuation . - pubmed
CONCLUSIONS : Recognition of the imaging manifestations of fibrodysplasia ossificans progressiva is imperative to early diagnosis in order to appropriately direct patient care and preclude unnecessary biopsies or surgical procedures . - pubmed
CONCLUSION : Our analysis indicates that naproxen can decrease the occurrence of heterotopic ossification without increasing complications in hip surgery patients . - pubmed
It nevertheless represents a major health problem in these patients , and is associated to life - threatening complications including increasing risk of cardiovascular pathologies . - pubmed
METHODS AND FINDINGS : To achieve this , we have first fully characterized the metabolic deregulations in these patients by conducting a longitudinal retrospective study , in children with achondroplasia Anthropometric , densitometric measures as well as several blood parameters were recorded and compared between three age groups ranging from [ 0 - 3 ] , [ 4 - 8 ] and [ 9 - 18 ] years old . - pubmed
Because it is not associated with diabetes , the atypical obesity has not been studied in the past even though it is recognized as a real problem in these patients . - pubmed
CONCLUSION : This study demonstrate that achondroplasia patients develop an atypical obesity with preferential abdominal obesity not associated with classical complications . - pubmed
These data strongly suggest that this common complication of achondroplasia should be included in the clinical management of patients . - pubmed
RESULTS : Orthostatic hypotension was present , depending on applied definition , in 34.5 % of the individuals at 1 min , 38.3 % at 3 min ; 44.9 % on either 1 or 3 min , and 27.8 % individuals in both measurements . - pubmed
In the second case , a patient with a pancreatic head adenocarcinoma with duodenal invasion that precluded major papillae identification was submitted to a choledochoduodenostomy . - pubmed
The tri - axial acceleration signals were converted into 2D acceleration images and a Convolutional Neural Network ( CNN ) was trained to recognize the differences between non - medicated ADHD children and their paired controls . - pubmed
Hip involvement in patients with calcium pyrophosphate deposition disease : potential and limits of musculoskeletal ultrasound . - pubmed
DESIGN : Fifty consecutive patients with " definite " CPPD and 40 age / sex / body mass index - matched disease controls who had undergone hip CR within the previous six months were enrolled . - pubmed
After their entrance , CNTs reach the CNS where they may cause cytotoxicity of selected neurons in several CNS regions , impairing molecular pathways and contributing to the onset and progression of chronic brain inflammation , microglia activation and white matter abnormalities with an increased risk for autism spectrum disorders , lower IQ in children , neurodegenerative diseases and stroke . - pubmed
Indigofera oblongifolia protects against trypanosomiasis - induced spleen injury . - pubmed
BACKGROUND : Trypanosomiasis is a neglected tropical disease , transmitted by blood - sucking insects and can affect humans and animals , depending on the species of Trypanosoma parasite . - pubmed
Indigofera oblongifolia leaf extract ( IOE ) has been shown to treat blood stage malaria . - pubmed
Anemia was apparent during the course of infection in T. - pubmed
evansi - induced spleen injury in mice . - pubmed
This study aimed to test the correlation of functional outcome in patients with pelvic fractures with the postoperative radiographic quality of reduction . - pubmed
METHODS : Consecutive patients with an isolated traumatic pelvic fracture that required closed or open reduction between 07/2015 and 07/2017 and had a completed follow - up of at least 6 months were included ( N = 31 , mean age 50 years , SD 21 years , range , 16 to 88 years ) . - pubmed
The 13 - gene - based classifier described in the current study may be used as a potential biomarker to predict the effects of fluorouracil - based chemotherapy in patients with CRC . - pubmed
Results : A total of 2032 Escherichia coli ( 875 ESBL - producing ) and Klebsiella pneumoniae ( 157 ESBL - producing ) strains , and 371 other Enterobacteriaceae strains , were isolated from patients with bloodstream infections ( BSIs ) . - pubmed
We herein review alterations in angiogenesis observed in human and experimental diabetes and how they contribute to diabetes onset and development of vascular complications . - pubmed
In a study of visual complications following head trauma , only 4.4 % of patients suffered from chiasmal injuries . - pubmed
We report the one - year follow - up of clinical , visual field , and MRI findings of a patient with complete transection of the optic chiasm following head trauma . - pubmed
This study compared the impact of nano - ubiquinone ( Nubiq ) with native ubiquinone ( ubiq ) reducing damage induced by Paracetamol - toxicity in rats . - pubmed
Systematic analysis of lncRNA expression profiles and atherosclerosis - associated lncRNA - mRNA network revealing functional lncRNAs in carotid atherosclerotic rabbit models . - pubmed
Atherosclerosis was induced in rabbits ( n = 3 ) carotid arteries via a high - fat diet and balloon injury , while age - matched rabbits ( n = 3 ) were treated with normal chow as controls . - pubmed
We provided an ASLMN of atherosclerosis development in carotid arteries of rabbits and probable targets which may lay the foundation for future research of clinical applications . - pubmed
These include , the multiplex , magnetic bead - based immunodiagnostics for both Lassa virus antigens and antibodies ; molecular probe - based quantitative real - time PCR for genomic signatures ; rapid diagnostics tests that detects the most prevalent West African lineages ; and the successful utilization of next - generation sequencing technology to diagnose and characterize Lassa virus in West Africa . - pubmed
In conclusion , PV mouth region appear to be a most susceptible to adrenergic proarrhythmia in mice . - pubmed
The patient with bronchial asthma had multiple sclerosis and was treated using natalizumab . - pubmed
The patient was referred to our department because of a persistent cough . - pubmed
STUDY DESIGN / MATERIALS AND METHODS : Patients with eyebrow tattoos underwent treatment with dual - wavelength picosecond Nd : YAG laser at 1,064 - nm with a 3 mm spot size and fluence of 4 - 4.6 J / cm2 . - pubmed
PLA modification significantly improved the cytocompatibility of PEI , PEI - PLA copolymer showed much higher cell viability than PEI as verified in three different human cancer cell lines ( HCT116 , HepG2 and SKOV3 ) . - pubmed
CASE REPORTS : Our three cases are representative of sleep - disordered breathing that occurred as a consequence of VNS activity in patients with refractory epilepsy . - pubmed
Sleep apnoea was observed in two patients and stridor in one patient . - pubmed
CONCLUSIONS : Given the high prevalence of sleep apnoea - hypopnoea syndrome in patients with refractory epilepsy , implantation of VNS should be ideally preceded by an assessment of the breathing during sleep . - pubmed
Impact of breed on canine humeral condylar fracture configuration , surgical management , and outcome . - pubmed
OBJECTIVE : To report the prevalence , configuration , risk factors , fixation methods and outcomes after repair of humeral condylar fractures ( HCF ) in dogs . - pubmed
METHODS : Medical records of dogs referred between January 2010 and August 2018 were searched for HCF . - pubmed
RESULTS : Dogs with HCF represented 112 of 43 325 ( 0.26 % , 95 % CI 0.22 - 0.31 ) referrals . - pubmed
Lameness was scored as 1 of 5 ( median ) in the 85 dogs with initial follow - up ( median 6 weeks ) after HCF repair . - pubmed
CONCLUSION : French bulldogs and spaniels were predisposed to HCF , and medial HCF were more common in French bulldogs . - pubmed
Preeclampsia is a potentially life - threatening multisystem disease affecting 4 % to 8 % of pregnant women after the 20th week of gestation . - pubmed
Patients ' sex , age , comorbidities , anatomic location of the wound , and the indications for ciNPWT were recorded . - pubmed
Late - term seroma and hematoma formation were encountered in two patients . - pubmed
Indications for ciNPWT utilization were preventing dehiscence , seroma , and hematoma formation in the majority of the patients . - pubmed
The relevance of the ectoparasitic mite Varroa destructor acting as mechanical and biological virus vector for the enhanced virulence of certain viruses or mite selected virus strains is carefully considered . - pubmed
The combination of endoscopic molecular imaging and photoimmunotherapy used in initial treatment may avoid the need of repeat transurethral resection in strictly selected patients and improve oncological outcomes such as recurrence - free survival and overall survival after operation . - pubmed
Impact of dedicated infectious disease teamwork on the treatment and prognosis of patients with diabetic foot infection . - pubmed
More human deaths have been attributable to Mycobacterium tuberculosis than any other pathogen , and the epidemic is sustained by ongoing transmission . - pubmed
A Blood - based Gene - expression Scoring System for Cancer Screening in Patients With Branch - duct Intraductal Papillary Mucinous Neoplasms . - pubmed
BACKGROUND : In patients with branch - duct intraductal papillary mucinous neoplasms ( BD - IPMN ) , we aimed to develop a novel blood - based biomarker utilizing a gene - expression profile for the detection of pancreatic malignancies , such as IPMN - derived carcinoma ( IPMC ) or pancreatic ductal adenocarcinoma ( PDAC ) . - pubmed
PATIENTS AND METHODS : We enrolled 40 patients with pancreatic tumors ( 24 BD - IPMNs , four IPMCs and 12 PDACs ) and identified the characteristic gene - expression profiles in pancreatic malignancies . - pubmed
The result was validated in 14 patients ( five IPMNs , three IPMCs and six PDACs ) . - pubmed
CONCLUSION : We developed a blood - based gene expression scoring system for cancer screening in patients with BD - IPMNs . - pubmed
Application of an iris speculum for removing Soemmerring ring during secondary intraocular lens implantation in congenital cataract patients with small pupils . - pubmed
An application of the XpandNT iris speculum in eyes with small pupils during secondary intraocular lens ( IOL ) implantation in congenital cataract patients is described . - pubmed
Fourteen aphakic eyes from 10 consecutive patients were studied retrospectively ; pupil expansion was achieved in all 14 eyes intraoperatively without serious intraoperative or postoperative complications . - pubmed
The XpandNT iris speculum was a safe and excellent tool for removing Soemmerring ring and solving small pupil problems during secondary IOL implantation in pediatric cataract surgery patients . - pubmed
Altered gene expression profile of Wolbachia pipientis wAlbB strain following transinfection from its native host Aedes albopictus to Aedes aegypti cells . - pubmed
The Aedes albopictus - derived strain wAlbB is promising in this regard . - pubmed
Patient 's demographic features , pre - operative signs and symptoms , details of rendered clinical procedures , follow - up visits , clinical and radiographic findings were recorded . - pubmed
Hepatoma , host liver , and normal rat liver neutral lipids as affected by diet . - pubmed
Groups of normal and hepatoma ( 7288CTC ) bearing rats were maintained on normal chow and fat - free diets for 4 weeks . - pubmed
The unchanged high level of essential fatty acids in the hepatoma lipids from the fat - free fed animals demonstrates the hepatoma 's ability to absorb and conserve specific fatty acids . - pubmed
Anatomic , clinical , and digestion analyses were done on 18 human urinary bladder polyps from patients with Schistosoma haematobium infections . - pubmed
Because of the high sensitivity and broad - spectrum reactivity , this technique could be useful for studying the pathogenesis and laboratory diagnosis of inclusion body hepatitis caused by several serotypes of AAV . - pubmed
Results of its transplantation on long not - healing donor wounds in 13 patients after autodermatoplastic operations have been studied . - pubmed
We studied a family in which one out of two children presented a non - salt wasting form of CAH . - pubmed
Patients with the X - linked type are highly susceptible to infections ; those with the autosomal recessive form may be less severely affected . - pubmed
As a step in the understanding of the molecular genetics of this form of ITP we have determined the nucleotide sequences of expressed V region genes selected from a panel of five human lymphoblastoid cell lines derived from patient DM . - pubmed
In a randomized comparative study , 83 male patients suffering from acute uncomplicated gonococcal urethritis were treated with a single dose of either 0.8 g pefloxacin , given orally , or 1.0 g cefotaxime , given intramuscularly . - pubmed
Postgonococcal urethritis was found in 9 % of the patients treated with pefloxacin and in 20 % of the patients treated with cefotaxime . - pubmed
No side effects were recorded in either groups of patients except that 46 % of the patients treated with cefotaxime reported mild pain at the injection site . - pubmed
Liver tumor promoters and other mouse liver carcinogens . - pubmed
Mouse liver tumors are important end points for safety assessment of chemicals in rodent carcinogenicity assays . - pubmed
If test mice have spontaneous tumors of high or low background incidence , the promotion of these tumors or of spontaneously initiated or susceptible cells may provide a basis for carcinogenesis induced by these compounds . - pubmed
Experimental systems have been developed to study the mechanisms of tumor promotion in mouse liver . - pubmed
These models should significantly advance research into mechanisms of hepatocarcinogenesis and tumor promotion in mouse liver and may subsequently be used for human risk assessment . - pubmed
Enhanced arrhythmogenicity of Freon 113 by hypoxia in the perfused rat heart . - pubmed
The interaction of Freon 113 ( 1,1,2 - trichloro-1,2,2 - trifluoroethane ) and hypoxia on the heart conduction system was studied using electrocardiogram monitoring of isolated perfused rat hearts . - pubmed
In the discussion of the responsibilities of society to the HIV infected and uninfected , a serious question seems to have been left out of the picture : To what extent are people who are not infected , have no special relationship to the infected and have no professional responsibilities for the care of AIDS patients under an obligation to come to the aid of people with the HIV ? - pubmed
Histological distribution was : follicular small cleaved cells 70 patients , follicular mixed 31 patients , small cells CLL type 12 patients . - pubmed
In a study of 54 women admitted to a day - care unit for this procedure , validated measures were utilized to assess the incidence , intensity and duration of pain after tubal ligation ( McGill Pain Questionnaire ) and the impact of pain on the activities of daily living ( Modified Functional Assessment Inventory ) . - pubmed
In Timm 's sulfide silver preparations , intragranular and supragranular mossy fiber staining is found to be much more prevalent in the temporal dentate gyrus of the spontaneous epileptic mouse , tottering , than at matching levels in unaffected littermate controls . - pubmed
In a study of 394 homosexual men recruited at the primary care level the prevalence of antibody to human T - lymphotropic retrovirus ( HTLV - III ) was higher among those with lymph node enlargement than among controls . - pubmed
Correlation between spiramycin treatment and negative results of mouse inoculation of placental material suggests that spiramycin might decrease the risk of materno - fetal transmission of toxoplasma by reducing the severity and duration of toxoplasmic placentitis . - pubmed
The authors report the case of an isolated supratentorial hemangioblastoma occurring in a woman operated on for a cerebellar hemangioblastoma twenty years before . - pubmed
Acute orthostatic hypotension is a common occurrence during a patient 's first experiences out of bed after surgery or a period of immobility . - pubmed
[ Rabies ; epidemiological aspects of animal attacks and frequency reported to the anti - human rabies service in Araguari , Minas Gerais ] . - pubmed
Vitrectomy surgery is effective for diabetic vitreous haemorrhage and traction retinal detachment , producing improved vision in most patients , but only a relatively small percentage of patients so treated recover good visual acuity ( greater than or equal to 6/12 ) . - pubmed
The primary care physician who deals with diabetic patients should be familiar with the lesions of diabetic retinopathy and with current therapeutic modalities . - pubmed
He should perform an examination of the posterior retina with the direct ophthalmoscope on each diabetic patient at each visit , and should institute prompt referral to an ophthalmologist at the first sign of change . - pubmed
Periodic examination of all diabetic patients by an ophthalmologist should be conducted at the intervals recommended in the previous section . - pubmed
Both combination drugs have similar serum half - life values in persons with normal renal function ( half - life of 8 to 12 hours ) , but the sulphamethoxazole metabolites are retained more than trimethoprim in reduced renal function . - pubmed
One hundred eleven patients were treated for upper extremity complications due to therapeutic agents . - pubmed
One patient had a persistently raised free T4 concentration and was considered to be thyrotoxic . - pubmed
Experimental development of a cambendazole - resistant strain of Haemonchus contortus in sheep . - pubmed
[ Sodium and potassium in serum and sputum of patients with bronchial asthma ] . - pubmed
[ Acute pericarditis in children ] . - pubmed
Pulmonary parenchymal defects in dogs following prolonged cigarette smoke exposure . - pubmed
Goodson and Hunt showed that wound healing is impaired in streptozotocin ( Sz ) diabetic rats ; we speculated that this impairment results from defective early inflammatory responses to wounding . - pubmed
Because we had shown that supplemental vitamin A stimulates the early inflammatory response to wounding in nondiabetic rats , we studied the effect of supplemental vitamin A on wound healing in rats with Sz - induced diabetes . - pubmed
Two - thirds of the rats were injected ( intravenously ) with Sz 60 mg / kg body weight . - pubmed
All of these rats became diabetic ( hyperglycemia greater than 350 mg / dl , hyperphagic , polydipsic , polyuric , glycosuric greater than 2 % ) . - pubmed
The wounds of Group 2 rats healed poorly compared to Group 1 ( breaking strength of skin incisions , 308 + /- 19 g vs 584 + /- 23 g , p less than 0.001 ; hydroxyproline of the sponge reparative tissue , 0.87 mg vs 2.40 mg/100 mg sponge p less than 0.001 ) . - pubmed
Supplemental vitamin A ( Group 3 ) did not affect the hyperglycemia , hyperphagia , polydipsia or glycosuria , but increased the breaking strengths of the incisions of the diabetic rats ( 468 + /- 40 g , p less than 0.001 ) , and the sponge hydroxyproline ( 2.38 mg/100 mg sponge , p less than 0.001 ) . - pubmed
The action of supplemental vitamin A in correcting the impaired wound healing , adrenal enlargement , thymic involution and lymphocytopenia of Sz - diabetic rats is independent of an effect on their disturbed carbohydrate metabolism . - pubmed
Fibroma in a Nine - banded armadillo ( Dasypus novemcinctus ) . - pubmed
An adult male Nine - banded armadillo ( Dasypus nonemcintus ) had a large tumour between the first and second phalanges of the right fore - foot . - pubmed
Diagnostic and prognostic significance of total bile acids concentrations has been evaluated in 26 patients with acute viral hepatitis . - pubmed
A remarkable rise in serum bile acids concentration has been showed in acute stage of hepatitis ; the level of cholates is significantly higher in cholangitic jaundice , but difference is not found in respect of patients with extrahepatic cholestasis . - pubmed
A patient is presented who had severe headache and then developed a stuttering course of clinical neurological deficits . - pubmed
A prospective review of 272 institutionalized cerebral palsy residents was undertaken in order to determine the incidence and characteristics of neuromuscular scoliosis in this population . - pubmed
The mouse MXT mammary and the human J82 and T24 bladder tumor cell lines were used in this study . - pubmed
A patient with navel metastasis from ovarian carcinoma was treated by immunotherapy and neo - adjuvant intraarterial infusion chemotherapy ( OK-432 i.c . - pubmed
There were two patients with adrenoleukodystrophy , four with dentato - rubro - pallido - luysian atrophy , three with familial spastic paraplegia , two with myotonic dystrophy and three with dementia of unknown origin . - pubmed
Selection for eight - week body weight in two randombred chicken populations under altered water to feed ratios . - pubmed
However such patients are usually at greater risk from systemic relapse . - pubmed
Tabulations and expectations regarding the genetics of human hypertension . - pubmed
Results from family studies suggest several possible single gene traits may be related to essential hypertension in humans . - pubmed
Eight genetic loci ( on chromosomes 1 , 6 , 8 , 17 and 19 ) are possibly related to essential hypertension in humans and are also reviewed . - pubmed
The study objective was to identify prognostic factors associated with survival in patients treated for acute leukemias who developed invasive aspergillosis ( IA ) during induction therapy . - pubmed
There was no statistical difference between the patients who survived and those who died in relation to the mean time of onset of IA or the total and mean daily dose of amphotericin B. - pubmed
On the other hand a favourable outcome correlated strongly with complete leukemic remission ( p & lt ; 0.0001 ): all but one of the patients with objective residual leukemia died of IA , whereas all those who achieved complete hematological remission survived . - pubmed
In conclusion , it seems that the main vital prognostic factor in these leukemic patients with IA was the achievement of complete remission . - pubmed
We were unable to control IA in 10 of 11 patients with refractory leukemia , regardless of neutropenic status , despite early administration of high - dose amphotericin B. - pubmed
[ Noninvasive ventilator support in patients with chronic obstructive pulmonary disease . - pubmed
Three hundred and eighty - one consecutive patients referred to our Nuclear Medicine Service from the Cardiology Department during a period of two years have been studied to evaluate Coronary Artery Disease ( CAP ) using 99mTc - MIBI single photon emission computed tomography ( SPECT ) . - pubmed
The sensitivity and specificity for detecting CAD in the whole group of patients , referred ( n = 161 ) or not ( n = 220 ) for coronary angiography , were calculated following Diamond 's method , and were found to be 87 % and 92 % , respectively . - pubmed
The ] purpose of this report is to describe three patients with levonorgestrel implants ( Norplant system ) who developed TTP . - pubmed
CASES : A 24 - year - old woman with levonorgestrel implants in place for 7 months was admitted to our hospital for treatment of TTP . - pubmed
In this paper , four patients with gyrate atrophy are described . - pubmed
All patients had visual impairment , mental retardation , hyperornithinemia , hypolysinemia , ornithinuria and lysinuria . - pubmed
It is suggested that gyrate atrophy must be considered in all patients with chorioretinal atrophy . - pubmed
Effect of thyroid deficiency on Go alpha - subunit isoforms in developing rat cerebral cortex . - pubmed
Serial undiluted passages were performed with the PUR46 strain of TGEV in swine testis ( ST ) cells . - pubmed
Coronal suture pathology and synostotic progression in rabbits with congenital craniosynostosis . - pubmed
The purpose of the present study was to describe coronal suture pathology and cross sectional synostotic progression in an inbred strain of rabbits with congenital craniosynostosis . - pubmed
Findings demonstrate that coronal suture synostosis in the congenital rabbit model ( 1 ) begins early during suture morphogenesis ( before 25 days of gestation ) ; ( 2 ) consistently radiates from a single focus corresponding to a normal interdigitating region ( i.e. - pubmed
Of the 108 cases , 96 had age - related macular degeneration , 6 had angioid streaks and 3 had degenerative myopia . - pubmed
Right internal carotid arteries of 36 rabbits were embolized using aged heterologous thrombi . - pubmed
RESULTS : Patients who underwent definitive surgery for breast cancer in the follicular phase had a slightly worse disease - free survival than those operated on during the luteal phase ( five - year DFS percentage : 53 % versus 58 % ; hazard ratio , 1.13 ; 95 % confidence interval ( CI ) , 0.94 - 1.38 ; P = 0.20 ) . - pubmed
The effect was significantly greater for the subpopulation of 300 patients with ER - negative primaries ( P = 0.02 interaction effect ; five - year DFS percentages 42 % vs. 59 % ; hazard ratio 1.60 ; 95 % CI , 1.12 - 2.25 ; P = 0.008 ) . - pubmed
Hyperinsulinemia in non - obese , non - diabetic subjects with isolated systolic hypertension . - pubmed
31 ( 91 % ) procedures were carried out without complications ; there was a false aneurysm in 1 patient ( 3 % ) and an occlusion of the brachial artery at the puncture site in 2 patients ( 6 % ) . - pubmed
The occluded vessels of two diabetic women had a reduced diameter at the level of 10 % of the standard distribution and an unfavorable ratio of sheat - to - vessel - diameter which lead initially to an obstruction of nearly 50 % of the vessel lumen during catheterization . - pubmed
Tono - Pen determination of intraocular pressure in patients with band keratopathy or glued cornea . - pubmed
AIMS : To evaluate the intraocular pressure ( IOP ) measurements in patients with band keratopathy or glued corneas obtained from affected and non - affected areas . - pubmed
METHODS : 15 patients with band keratopathy or glued corneas were prospectively recruited . - pubmed
RESULTS : Determination of IOP with the Tono - Pen was possible in all cases , while Goldmann tonometry was not performed in three patients because of severe corneal irregularities . - pubmed
CONCLUSION : In patients with band keratopathy or glued corneas determination of IOP by Tono - Pen tonometry varies from affected to non - affected area . - pubmed
Six of the 66 patients had malignant tumors . - pubmed
Coumarin skin necrosis occurs almost exclusively in patients with venous thrombosis between the 3rd and 10th day after beginning anticoagulation . - pubmed
CONCLUSION : Peritoneal scintigraphy is useful in the evaluation and assessment of CPD patients who develop anatomical problems ( such as anterior abdominal , pleural - peritoneal , inguinal , and genital leaks ) and problems with ultrafiltration and/or drainage . - pubmed
Reports on 68 patients with DNH were obtained . - pubmed
Reports on 64 patients with neonatal haemangiomatosis limited to only the skin and liver were also obtained . - pubmed
The clinical features and outcome of patients with only cutaneous and hepatic haemangiomas were similar to those of patients with DNH . - pubmed
The inclusion criteria for DNH should be expanded to include similar patients with only cutaneous and hepatic haemangiomas . - pubmed
These data indicate that strains commonly classified as Streptococcus thermophilus may belong to different taxa . - pubmed
, all these strains indeed belong to the same species , Lactococcus lactis . - pubmed
Previously , we have reported that L - deprenyl decreased the incidence of mammary tumors and pituitary tumors in old acyclic rats . - pubmed
Female Sprague - Dawley rats with DMBA - induced mammary tumors were injected ( sc ) daily with 0.25 mg or 5.0 mg of deprenyl / kg BW or the vehicle ( saline ; control ) for 12 wk . - pubmed
The prevalence of Chlamydia pneumoniae antibodies in Thai patients with coronary artery disease . - pubmed
Blood samples were obtained from 243 consecutive coronary artery disease ( CAD ) patients ( 177 male , 66 female ) aged 35 - 78 years ( mean , 61 years ) admitted for coronary angiography because of suspected coronary heart disease , and from 115 blood donors ( 91 male , 24 female ) aged 25 - 60 years ( mean , 47 years ) . - pubmed
thompsoni strain HnC are active against the codling moth , Cydia pomonella , a major pest of orchards . - pubmed
Medullary thyroid carcinoma was found in 7 patients ( aged 5 - 56 years ) , C - cell hyperplasia in 6 patients ( aged 13 - 40 years ) , and normal histology in a single patient ( aged 27 years ) . - pubmed
One patient with medullary thyroid carcinoma died of metastases ( aged 12 years ) . - pubmed
The week prevalence of back and neck pain was evaluated at these test moments in extended samples of intervention children ( n = 347 ) and controls ( n = 349 ) . - pubmed
The aim of the present study was to investigate the pharmacokinetics of oestriol in plasma in the dog after repeated oral administration of oestriol tablets , a preparation intended for the treatment of urinary incontinence in the bitch . - pubmed
Adverse drug events among elderly outpatients are common and preventable . - pubmed
Experiments were performed using HT-22 , an immortalized mouse hippocampal cell line , and SK - N - SH , a human neuroblastoma cell line . - pubmed
[ Effect of drugs on the temporal sphygmogram in humans and its significance in experimental headache ] . - pubmed
[ Research on the electrophoretic fractionation of the serum of patients with gouty arthropathies ] . - pubmed
Diagnostic coronary angiography induces a systemic inflammatory response in patients with stable angina . - pubmed
The aim of this study was the determine whether diagnostic coronary angiography performed in patients with stable angina triggers a systemic inflammatory response . - pubmed
METHODS : We prospectively studied patients with chronic stable angina undergoing either coronary angiography ( n = 13 ) or coronary angiography followed by PCI ( n = 13 ) . - pubmed
Patients with periprocedural myocardial necrosis were excluded . - pubmed
CONCLUSION : Uncomplicated diagnostic coronary angiography triggers a systemic inflammatory response in patients with stable angina . - pubmed
METHODS : Seventy eyes of 35 patients with rhegmatogenous retinal detachments were included in this study . - pubmed
None of the patients had pathologic myopia or a history of ocular surgery . - pubmed
Consistent with this hypothesis , we detected increased hypothalamic Mch mRNA levels in agouti ( Ay ) mice ( by 102 % ; P & lt ; 0.05 ) , a model of genetic obesity resulting from impaired melanocortin signaling , compared to wild - type controls . - pubmed
We therefore investigated the effects of energy restriction on hypothalamic Mch gene expression in both Ay mice and in wild - type mice with diet - induced obesity ( DIO ) . - pubmed
Determination of relapse risk based on assessment of minimal residual disease during complete remission by multiparameter flow cytometry in unselected patients with acute myeloid leukemia . - pubmed
Quantification of minimal residual disease ( MRD ) reveals significant prognostic information in patients treated for acute myeloid leukemia ( AML ) . - pubmed
DNA - DNA pairing studies showed that the unidentified organism displayed more than 70 % relatedness to the type strains of S. - pubmed
On the basis of phenotypic and molecular genetic evidence , it is proposed that the unknown Streptococcus isolates from ovine and caprine mastitis be classified as a novel subspecies , Streptococcus equi subsp . - pubmed
The type strain is CECT 5772(T ) (= CCUG 47520(T)=Mt 167(T ) ) . - pubmed
ni High 5 cells were permissive to ThorMNPV in terms of infection and viral DNA transfection , but SF-21 was less permissive and the infection process was slower . - pubmed
This case highlights the difficulties encountered in assessing patients with superior premorbid function in the early stages of Alzheimer ' s disease , and reveals the value of serial MRI and neuropsychological assessment in detecting and monitoring early neurodegenerative disease . - pubmed
MATERIALS AND METHODS : 137 serum and whole blood samples collected from 31 ovarian cancer patients during their consecutive hospital stays . - pubmed
Thrombocytosis occurred in 45 % patients before treatment , and in none when the 6th course of chemotherapy was given . - pubmed
EXPERIMENTAL DESIGN : Human pancreatic cancer cells were injected into the pancreas of severe combined immunodeficient mice . - pubmed
A delicate balance between normalization and excessive regression of tumor vasculature is important when initiating alternative combinatorial regimens for treatment of patients with pancreatic cancer . - pubmed
Chronic bronchitis is the most frequent late respiratory disease among Iranians exposed to mustard gas during the Iraq - Iran war . - pubmed
The aim of this study was to investigate efficacy of oral and intravenous corticosteroid therapy in improving lung function in mustard gas induced chronic bronchitis patients . - pubmed
65 mustard gas - exposed chronic bronchitis patients , who were not responsive to standard treatments in exacerbation occasions , were randomly divided into two groups : an intravenous group ( 39 patients ) receiving 500 mg intravenous methylprednisolone daily , and an oral group ( 26 patients ) receiving 1 mg / kg oral prednisolone daily . - pubmed
Since short - term corticosteroid therapy has a significant effect on lung function of almost fifty percent of patients with mustard gas - induced chronic bronchitis in exacerbation occasions , we suggest a short - term bolus steroid treatment to triage the patients into responders and non - responders for subsequent treatment . - pubmed
Mental dysfunction of 130 children aged 0 - 14 years with a history of family physical abuse was studied using a number of known methods adapted for early aged children including an original scale of mental dysfunction assessment , which has been elaborated in Mental Health Research Center ( Moscow ) . - pubmed
PURPOSE : The purpose of this research was to evaluate pain and anxiety levels in patients undergoing chemotherapy via central venous catheter ( CVC ) and peripheral venous access ( PVA ) . - pubmed
METHOD : The sample consisted of 56 cancer patients undergoing at least one chemotherapy treatment cycle . - pubmed
They were divided into two groups based on the administration method of the chemotherapeutic drug : the experimental group ( patients with CVC ) and the control group ( patients with PVA ) . - pubmed
Three isolates of Infectious bursal disease virus ( IBDV ) , designated UPM04178 , UPM04190 and UPM04238 , were obtained from severe outbreaks of infectious bursal disease ( IBD ) in Malaysia in 2004 . - pubmed
Phylogenetic analysis revealed clustering of the three isolates with vvIBDV strains . - pubmed
Evolutionary relatedness of the three isolates to vvIBDV strains was demonstrated by three phylogenetic methods : bootstrap values of 100 % , 95 % and 90 % for nucleotide sequences and those of 58 % , 86 % and 96 % for amino acid sequences were obtained by the distance , maximum parsimony and maximum likehood methods , respectively . - pubmed
Trough serum concentrations of infliximab were measured in 6 adult patients with various diseases and in 5 pediatric patients with Crohn ' s disease . - pubmed
Twenty patients undergoing emergency Caesarean section with spinal anesthesia ( spinal group ) were also investigated to confirm that epidural block is effective for postoperative pain . - pubmed
Discontinuation of tamsulosin treatment in men with lower urinary tract symptoms : a pilot study . - pubmed
OBJECTIVES : Since little investigation has been undertaken to determine if alpha1 - blockers should be given continuously to sustain their efficacy , we conducted a pilot study to determine symptom change following discontinuation of tamsulosin after an initial improvement in symptoms in men with lower urinary tract symptoms ( LUTS ) . - pubmed
PATIENTS AND METHODS : Thirty - three of 78 patients with mild - to - moderate prostate hyperplasia , who had symptom improvement according to the International Prostate Symptom Score ( IPSS ) to & lt;10 or the quality of life ( QOL ) index to & lt ; or =3 after initial treatment with tamsulosin , were enrolled in this study . - pubmed
METHODS : A prospective study of 100 unrelated blood donors and 121 consecutive patients with AAU was carried out . - pubmed
Radiological examination of the sacroiliac joints was conducted in patients with low back pain or arthralgias . - pubmed
In response to glucocorticoid - induced cytotoxicity , microvascular endothelial cells ( MVEC ) derived from human brain were highly susceptible , MVEC derived from human lung and human liver sinusoidal endothelial cells were sub - sensitive , while AdrEC were highly resistant . - pubmed
The importance of this case is that the patient presented at the clinic with only lumbar pain . - pubmed
Only Amitraz ( Preventic ) provided total control on transmission ( no dogs were infected ) , whereas with Frontline , Advantix , or Scalibor , the rate of infection varied among the dogs . - pubmed
Neurotoxic lesions of the caudate - putamen on a reaching for food task in the rat : acute sensorimotor neglect and chronic qualitative motor impairment follow lateral lesions and improved success follows medial lesions . - pubmed
Although changes in the end - point measure of success document the effects of neurotoxic cellular damage to the caudate - putamen and its treatment in rodents , there has been no examination of the cause of change in success after neurotoxic lesions of the striatum . - pubmed
The patient was a 61 - year - old man with chronic hepatitis C who achieved a sustained virological response to interferon therapy in 1993 . - pubmed
Even if patients with chronic hepatitis C have achieved a sustained virological response to interferon therapy , patients with risk factors for the development of hepatocellular carcinoma , such as being a male of advanced age and with progressive fibrosis of the liver , should receive careful long - term follow - up . - pubmed
[ Upper gastrointestinal hemorrhage in a cardiac patient with chronic renal insufficiency ] . - pubmed
Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents : approaches to dose selection . - pubmed
For more than three decades chronic studies in rodents have been the benchmark for assessing the potential long - term toxicity , and particularly the carcinogenicity , of chemicals . - pubmed
Altered intestinal permeability in patients with primary fibromyalgia and in patients with complex regional pain syndrome . - pubmed
OBJECTIVES : The pain intensity of patients with FM has recently been reported to be correlated with the degree of small intestinal bacterial overgrowth ( SIBO ) . - pubmed
We therefore examined the IP in a group of patients with primary FM and in two control groups , healthy volunteers and patients with an unrelated chronic pain syndrome , complex regional pain syndrome ( CRPS ) . - pubmed
We hypothesized that patients with FM , but not volunteers or those patients with CRPS , would have altered IP . - pubmed
RESULTS : Forty patients with primary FM , 57 age- and sex - matched volunteers and 17 patients with CRPS were enrolled in this study . - pubmed
Participants diagnosed with ASDs had significantly ( P & lt ; 0.001 ) decreased plasma reduced GSH , plasma cysteine , plasma taurine , plasma sulfate , and plasma free sulfate relative to controls . - pubmed
The present observations are compatible with increased oxidative stress and a decreased detoxification capacity , particularly of mercury , in patients diagnosed with ASDs . - pubmed
Patients diagnosed with ASDs should be routinely tested to evaluate transsulfuration metabolites , and potential treatment protocols should be evaluated to potentially correct the transsulfuration abnormalities observed . - pubmed
UNLABELLED : The purpose of this study is to explore the clinical , biochemical and hormonal changes due to the use / prescription of rosiglitazone to women with PCOS . - pubmed
MATERIALS AND METHODS : The study includes 15 women with PCOS and clinical data on insulin resistance , that were treated with a daily dose of 4 mg rosiglitazone ( Avandia ) for 3 months . - pubmed
The use of wireless capsule enteroscopy in a preclinical study : a novel diagnostic tool for indomethacin - induced gastrointestinal injury in experimental pigs . - pubmed
METHODS : The experimental animal species were small adult pigs ( n=10 ; body weight 30 - 35 kg ; 4 - 5 months old ) used for their relative physiological and metabolic resemblance to man . - pubmed
The following experimental methods were used for diagnostic verification of gastrointestinal lesions ( damage scale : 1 - erosions , red spots , inflammatory infiltration , 2 - single ulcers , 3 - strings of ulcers ): endoscopic image for the diagnostics of gastro - duodenal segment ( in vivo conditions ) , confocal laser microscopy ( ex vivo imaging ) and optical light microscopy ( in vitro ) , small intestinal imaging by means of wireless capsule enteroscopy ( in vivo ) , macroscopic findings and optical light microscopy ( after animal sacrifice ) . - pubmed
Interleukin-12 ( IL-12 )- deficiency promotes photocarcinogenesis in mice ; however , the molecular mechanisms underlying this effect have not been fully elucidated . - pubmed
We present the sixth known case of extragingival PA in the buccal mucosa , which occurred in an 88 - year - old woman . - pubmed
Efficacy and durability of the titanium mesh cage spacer combined with transarticular screw fixation for atlantoaxial instability in rheumatoid arthritis patients . - pubmed
SUMMARY OF BACKGROUND DATA : There have been few studies about atlantoaxial fusion rate and advantages for titanium mesh cage from comparison with AIBG in rheumatoid arthritis ( RA ) patients . - pubmed
METHODS : Between January 1998 and October 2007 , 55 RA patients were surgically treated for AAI . - pubmed
We also could prevent donor site morbidities frequently seen in patients with surgical treatment for AAI . - pubmed
BACKGROUND : Branch retinal vein occlusion ( BRVO ) is a common retinal vascular disorder of the elderly and both intravitreal triamcinolone acetonide ( TA ) and intravitreal bevacizumab were reported to be effective . - pubmed
BACKGROUND : It is necessary to develop a highly specific and sensitive assay to quantify the exact amount of hepatitis C virus ( HCV ) RNA in blood of patients with hepatitis C. - pubmed
The term catamenial epilepsy is used to describe the cyclical occurrence of seizure exacerbations during particular phases of menstrual cycle in women with preexisting epilepsy . - pubmed
METHODS : We examined the safety of proximal gastrectomy by analyzing the lymph node metastasis rate in 53 patients who underwent total gastrectomy due to proximally located early gastric cancer from January 2004 to December 2008 . - pubmed
Fifteen patients underwent proximal gastrectomy using a new method which left no gastrostomy wound for the insertion of a circular stapler in the remaining stomach . - pubmed
METHODS AND STUDY DESIGN : Clinical and imaging features of 31 male patients with breast lesions were retrospectively evaluated and correlated with core needle biopsy results . - pubmed
OBJECTIVES : We evaluated the efficacy and safety of the percutaneous ventricular assist device ( pVAD ) in patients in severe refractory cardiogenic shock ( SRCS ) despite intra - aortic balloon pump ( IABP ) and/or high - dose vasopressor support . - pubmed
RESULTS : Eighty patients had ischemic and 37 patients had nonischemic cardiomyopathy . - pubmed
CONCLUSIONS : The pVAD rapidly reversed the terminal hemodynamic compromise seen in patients with SRCS refractory to IABP and vasopressor support . - pubmed
RESULTS : We present the first report of an infected abdominal aortic graft , secondary to an ileal perforation , in a 76 - year - old woman presenting with bilateral iliopsoas abscess . - pubmed
The outbreak resulted in the death of 97 animals ( 42 cattle , 52 dogs , and 3 horses ) . - pubmed
[ Limb ischemic preconditioning decreases hippocampal ischemia / reperfusion injuries in rats ] . - pubmed
Global cerebral ischemia was performed by four vessels occlusion in rats . - pubmed
Second , we evaluated resected megacolonic specimens of four patients suffering from chronic Chagas ' disease . - pubmed
PURPOSE : Patients with hepatitis B e antigen ( HBeAg)-positive chronic hepatitis B , who achieve HBeAg seroconversion 6 months after completing 48 weeks of peginterferon alfa-2a therapy , have an increased chance of clearing hepatitis B surface antigen ( HBsAg ) during long - term treatment - free follow - up . - pubmed
Radioactivity of blood samples taken from thyroidectomized thyroid carcinoma patients after therapy with ( 131 ) I. - pubmed
BACKGROUND : Occasionally , blood samples may be required from thyroid cancer patients after they have been given the therapy dose of ( 131 ) I , as part of necessary medical management of comorbidities . - pubmed
The purpose of this study was to quantify the amount of radioactivity in blood samples taken from thyroidectomized thyroid carcinoma patients after the administration of therapeutic activities of ( 131 ) I. - pubmed
METHODS : For dosimetry purposes , serial blood sampling is performed on thyroidectomized thyroid carcinoma patients prior to therapy with ( 131 ) I. - pubmed
Here we describe how the use of near - infrared dyes and fluorescence laparoscopy could help improve tumour staging and therefore lead to better selection of patients for postoperative adjuvant chemotherapy . - pubmed
Evaluation of wound - healing formulation against sulphur mustard - induced skin injury in mice . - pubmed
Sulphur mustard ( SM ) is a bifunctional alkylating agent that causes cutaneous blisters in human and animals . - pubmed
Due to inevitable requirement of a wound - healing formulation against SM - induced skin lesions , efficacy of formulations including povidone iodine , Aloe vera gel , betaine or framycetin sulphate was evaluated in present study . - pubmed
Blood samples were collected from a cohort of children under intensive surveillance for Plasmodium falciparum parasitaemia and illness . - pubmed
The pathology database was queried for all patients with DCIS from January 2004 to September 2008 . - pubmed
METHODS : A retrospective , consecutive , noncomparative cases series of DALK procedures in a total of 806 eyes of 711 patients with stromal diseases and healthy endothelium performed between 2000 and 2009 . - pubmed
RESULTS : 9 ( 3.3 % ) of 270 patients underwent surgery to remove esophageal foreign bodies . - pubmed
[ Abnormal glucose tolerance in prepubertal patients with cystic fibrosis ] . - pubmed
PATIENTS AND METHODS : Retrospective study of 19 prepubertal CF patients ( 68 % males ) . - pubmed
In follow - up : 4/10 NGT patients developed AGT ( 3 IGT , 1 CFRD ) . - pubmed
The lateral RA was selected in children & gt;1 yr of age without abnormal migration or fusion of the kidney ( n=104 ) . - pubmed
BACKGROUND : Recent studies have identified HIV as a leading contributor to preterm delivery and its associated morbidity and mortality . - pubmed
This study was designed to determine the incidence and risk factors for preterm delivery in HIV positive Nigerians . - pubmed
HIV positive women with multiple pregnancies , symptomatic HIV infection at delivery and first trimester fetal exposure to PI based triple therapy were found to be at risk of spontaneous preterm delivery . - pubmed
BACKGROUND : To obtain a prognostic stratification model for resected gastric cancer patients . - pubmed
METHODS : The patient presented with a sternal mass 4 years after undergoing coronary artery bypass grafting for ischemic coronary artery disease . - pubmed
[ Bleeding in the appointment of dabigatran in the patients with renal insufficiency caused by coadministration of spironolactone and ACE inhibitors ] . - pubmed
It is a case report of bleeding when using dabigatran in patient with renal failure caused by the concurrent use of spironolactone and angiotensin - converting enzyme ( ACE ) inhibitors . - pubmed
The patient ( 75 years old ) at the decompensation of chronic heart failure in the background of persistent atrial fibrillation was appointed the combination of ACE inhibitors , spironolactone , and dabigatran . - pubmed
The complete clinical trials thus far have showen that those tested chemosensitizers only add limited or no benefits to cancer patients . - pubmed
Available evidence does not support the routine use of higher positive end expiratory pressure ( PEEP ) in patients with ARDS . - pubmed
CONCLUSIONS : A lumbar support pillow with a cut - out for the posterior pelvic tissues improved an objective measure of comfort in healthy individuals and patients with low back pain . - pubmed
Factors associated with initiation of chronic renal replacement therapy for patients with kidney failure . - pubmed
BACKGROUND AND OBJECTIVES : Patients with kidney failure sometimes do not receive chronic renal replacement therapy ( RRT ) , even though this may reduce their life expectancy . - pubmed
Neurocognitive functioning in patients with first - episode schizophrenia 1 year from onset in comparison with patients 5 years from onset . - pubmed
Therefore , we followed patients with first - episode schizophrenia to verify the course of these deficits . - pubmed
METHODS : In Study 1 , tests of neurocognitive functioning were administered to patients with first - episode schizophrenia ( FE group ) every 6 months . - pubmed
Here we report an in - depth evolutionary analysis of whole - genome sequence data of 45 H7N9 and 42 H9N2 viruses isolated from humans , poultry , and wild birds during recent influenza surveillance efforts in China . - pubmed
Our study identifies the pathways for the generation of diverse H7N9 genotypes in China and highlights the importance of monitoring multiple sources for effective surveillance of potential influenza outbreaks . - pubmed
A 2007 observational cohort study in Bihar of 251 patients with VL treated with 20 mg / Kg intravenous liposomal amphotericin B ( Ambisome ) demonstrated a 98 % cure rate at 6 - months . - pubmed
SIGNIFICANCE : This is the largest cohort of VL patients treated with 20 mg / kg Ambisome worldwide . - pubmed
OBJECTIVES : The purpose of this study was to assess the prevalence and characteristics of dental erosion in children aged 2 - 4 years old and 12 years old . - pubmed
Bartholin ' s Gland Abscesses Caused by Streptococcus pneumoniae in a Primigravida . - pubmed
In this report , we describe a case of Bartholin ' s abscess caused by Streptococcus pneumoniae in a 25 - year - old non - diabetic primigravida . - pubmed
METHODS AND RESULTS : We present a rare case of a 63 - year - old man with dermatomyositis as a paraneoplastic syndrome developing more than a year before clinical manifestations of tonsillar squamous cell carcinoma ( SCC ) . - pubmed
Circulating tumor cells ( CTCs ) can be detected in the blood of patients with nearly all types of locally and metastatic adenocarcinomas . - pubmed
BACKGROUND : Multiple independent culture - based studies have identified the presence of Pseudomonas aeruginosa in respiratory samples as a positive risk factor for bronchiolitis obliterans syndrome ( BOS ) . - pubmed
Night time symptoms ( snoring , frequent night awakenings , restless sleep ) were present in 294 children , and 161 children had daytime symptoms ( excessive daytime sleepiness , early morning fatigue , poor concentration at school ) . - pubmed
Heart rate variability is reduced in acromegaly patients and improved by treatment with somatostatin analogues . - pubmed
However , few data are available on cardiac autonomic functions and sympathovagal balance in acromegalic patients . - pubmed
OBJECTIVE : The aim of this study was to investigate both the time and frequency domain parameters of Heart Rate Variability ( HRV ) , in order to characterize the cardiac autonomic functions in patients affected by acromegaly . - pubmed
MATERIALS AND METHODS : This study enrolled 47 acromegalic patients ( 23 males , age 49.1 + - 13.5 years ) and 37 ( 13 males ) age matched ( 52.3 + - 13.3 years ) healthy subjects . - pubmed
The HRV of 28 acromegalic patients was studied before and after SSAs treatment . - pubmed
RESULTS : Acromegalic patients showed significantly lower SDNN and SDANN compared to controls . - pubmed
Diabetic and non - diabetic acromegalic patients showed decreased SDNN and SDANN , when compared to healthy subjects . - pubmed
Similar results were obtained analyzing patients affected by acromegaly and impaired glucose tolerance . - pubmed
Patients with ventricular arrhythmias in Lown classes 3 - 5 showed a decreased SDANN compared to patients in Lown class 0 - 2 . - pubmed
CONCLUSION : Cardiac autonomic functions and sympathovagal balance are altered in patients affected by acromegaly and could be ameliorated by SSAs therapy . - pubmed
HRV analysis allows an estimation of the autonomic sympathovagal balance and may be a useful clinical tool for the cardiac risk stratification in acromegalic patients . - pubmed
The aim was to assess the effect of omega-3 supplementation on Body Mass Index ( BMI ) , Wais - Hip Index ( WHI ) and body composition of obese women using bioelectrical impedance . - pubmed
Subjects 60 premenopausal obese women ( BMI & gt ; 30Kg / m2 ) were randomly assigned to 3 groups : Group 1 ) placebo , vitamin E ( 200 IU ) , group 2 ) 1 g of omega and group 3 ) 2 g of omega-3 . - pubmed
METHODS : This retrospective observational case series included 18 eyes ( 18 patients ) with typical exudative age - related macular degeneration with a baseline best - corrected visual acuity of 20 / 25 or better . - pubmed
CONCLUSIONS : Deterioration in visual acuity was noted in eyes with typical exudative age - related macular degeneration with good baseline visual acuity , suggesting the need for close patient monitoring and prompt treatment even in patients with good baseline visual acuity . - pubmed
OBJECTIVES : In this study , we aim to predict the recovery of upper limb function in patients in the acute phase of cerebrovascular disease . - pubmed
RESULTS : A total of 357 patients with cerebrovascular disease were analyzed on the basis of diagnosis [ cerebral infarction ( CI ; 77.6 % ) , cerebral hemorrhage ( CH ; 20.2 % ) , subarachnoid hemorrhage ( SAH ; 2.2 % ) ] . - pubmed
CONCLUSIONS : In this report , we described the study design and characteristics of patients with cerebrovascular disease at baseline . - pubmed
Prediction of need for surgery after endoscopic balloon dilation of ileocolic anastomotic stricture in patients with Crohn ' s disease . - pubmed
PATIENTS : All of the eligible patients with ileocolic anastomotic stricture attributed to recurrent Crohn ' s disease treated with endoscopic dilation between December 1998 and May 2013 were evaluated . - pubmed
Patients with concurrent enterocutaneous fistula or abdominal or pelvic abscess were excluded . - pubmed
RESULTS : A total of 185 patients with Crohn ' s disease ( 45.9 % women ; mean age , 43.1 years ; symptomatic strictures in 80 % ) underwent 462 endoscopic dilations of ileocolic anastomosis ( median per - patient dilations , 2 ; range , 1 - 3 ) . - pubmed
During a mean follow - up of 3.9 years , 27 patients ( 14.6 % ) required hospitalization without surgery for stricture - related symptoms , and 66 patients ( 35.7 % ) required subsequent salvage surgery . - pubmed
A 72 - year - old man presented to the high dependency unit following an elective incisional hernia repair . - pubmed
The in vitro study was conducted on human meningioma primary cells extracted from fresh tumors , allowing the assessment of somatostatin analogs at the concentration levels used in patients . - pubmed
We have demonstrated a co - operative action between everolimus and octreotide on cell proliferation in human meningiomas , including aggressive ones , establishing the basis for a clinical trial . - pubmed
Risk factors associated with end - stage renal disease ( ESRD ) in patients with atherosclerotic renal artery stenosis : a nationwide population - based analysis . - pubmed
Of note , our data showed that renal artery revascularization was associated with a lower risk of ESRD in ARAS patients in long - term follow - up . - pubmed
The interaction effects of aerobic exercise training and vitamin D supplementation on plasma lipid profiles and insulin resistance in ovariectomized rats . - pubmed
PURPOSE : The purpose of this study was to determine the interaction effects of aerobic exercise training and vitamin D supplementation on indices of obesity and plasma lipid profiles in ovariectomized ( OVX ) rats . - pubmed
Strain differences in antioxidants in rat models of cardiovascular disease exposed to ozone . - pubmed
We examined the hypothesis that antioxidant substances and enzymes in lung , heart and in bronchoalveolar lavage fluid ( BALF ) are altered in response to O3 in cardiovascular disease and/or metabolic syndrome ( CVD)-prone rat models . - pubmed
CVD rats tended to respond less to O3 than normal . - pubmed
In summary , large differences were observed between both normal and CVD rat strains in low - molecular weight antioxidant concentrations in lung , BALF and heart tissue . - pubmed
Wistar ( normal ) and JCR and SHHF ( CVD ) rats appeared to stand out as peculiar in terms of basal- or O3 - induced changes . - pubmed
RESULTS : Significant valvular heart disease increases perioperative risk in major non - cardiac surgery and increases long term patient morbidity and mortality . - pubmed
METHODS : Patients with a history of primary lateral patellar dislocation between 2008 and 2012 were prospectively identified . - pubmed
Characterizing knee anatomic imaging factors in the patient with a primary lateral patellar dislocation is a necessary first step in characterizing the ( potential ) differences between the primary and recurrent patellar dislocation patient . - pubmed
Biomechanical comparison of 3.0 mm headless compression screw and 3.5 mm cortical bone screw in a canine humeral condylar fracture model . - pubmed
METHODS : Bilateral humeri were collected from nine canine cadavers . - pubmed
CASE REPORTS : Case 1 was a 12 - year - old male patient with anisometropic " amblyopia " in the right eye , MRNF denser superiorly , a hypoplastic disc , and a myopic fundus with a flat intact macula . - pubmed
Case 2 was a 10 - year - old male patient with a constant left esotropia , MRNF denser superiorly , a hypoplastic disc , and a myopic fundus with a flat intact macula . - pubmed
Case 3 was a 58 - year - old female patient with a history of diabetic retinopathy OU , long - standing reduced vision in the right eye , MRNF denser superiorly , optic nerve hypoplasia , and a myopic fundus with an intact macula . - pubmed
CONCLUSIONS : This case series identifies three patients with the syndrome of MRNF , optic nerve hypoplasia , and anisomyopia in one eye with reduced vision and reports OCT findings using SD - OCT systems . - pubmed
Patients with this syndrome may have a guarded prognosis in the success of vision therapy . - pubmed
In view of the inter - individual differences in anatomy , physiological reserves , and severity of pathological processes , neuromonitoring may be a valuable method to evaluate the well - being of the nervous system during and after surgical interventions . - pubmed
Vitrectomy for complications of proliferative diabetic retinopathy in young adults : clinical features and surgical outcomes . - pubmed
PURPOSE : To investigate the clinical manifestations and surgical results after vitrectomy for proliferative diabetic retinopathy ( PDR ) in young patients . - pubmed
Patients with Type 1 and Type 2 diabetes mellitus subgroups shared similar clinical features and visual outcome . - pubmed
Methods : Ten patients ( 8 women and 2 men ) with skin - picking disorder ( per DSM-5 criteria ) were enrolled in the study . - pubmed
As a demonstration for mobile applications , these BJT sensors are further investigated by measuring chloride levels in artificial human sweat for potential cystic fibrosis diagnostic use . - pubmed
We report the clinical presentation , diagnostic approach , and therapy of four children with progressive pPACNS . - pubmed
In the present review , the beneficial effects of the most investigated nutraceutical compounds in the setting of human IBD are discussed . - pubmed
Unlike many of the nontyphoidal Salmonella serovars such as S. Typhimurium that cause restricted gastroenteritis , Salmonella Typhi is unique in that it causes life - threatening typhoid fever in humans . - pubmed
This article discusses the current understanding of typhoid toxin and potential directions for future research endeavors in order to better understand the contribution of typhoid toxin to S . - pubmed
This enabled the identification of a viral agent in 71.3 % ( 231/324 ) of unidentified surveillance samples , including common respiratory pathogens ( 100/324 ; 30.9 % ): enterovirus ( 16/100 ; 16.0 % ) , coxsackievirus ( 31/100 ; 31.0 % ) , echovirus ( 22/100 ; 22.0 % ) , human rhinovirus ( 3/100 ; 3 % ) , enterovirus genus ( 2/100 ; 2.0 % ) , influenza A ( 9/100 ; 9.0 % ) , influenza B , ( 5/100 ; 5.0 % ) , human parainfluenza ( 4/100 ; 4.0 % ) , human adenovirus ( 3/100 ; 3.0 % ) , human coronavirus ( 1/100 ; 1.0 % ) , human metapneumovirus ( 2/100 ; 2.0 % ) , and mumps virus ( 2/100 ; 2.0 % ) , in addition to the non - respiratory pathogen herpes simplex virus type 1 ( HSV-1 ) ( 172/324 ; 53.1 % ) and HSV-1 co - infection with respiratory viruses ( 41/324 ; 12.7 % ) . - pubmed
EDTA - induced pseudothrombocytosis and citrate - induced platelet agglutination in a patient with Waldenstrom macroglobulinemia . - pubmed
A patient had EDTA - induced pseudothrombocytosis and platelet agglutination in citrate blood samples . - pubmed
This is the case of a 43 years - old woman who presented with severe headaches 9 years ago ( 2008 ) . - pubmed
We report the case of a 56 - year - old man who presented a persistent urticarial rash and anaphylactic shock after a mitral valve repair operation . - pubmed
Materials and Methods : One hundred and twenty - seven patients with diabetes mellitus attending our outpatient were randomized into intervention ( n = 63 ) and control groups ( n = 64 ) . - pubmed
Patient education module consisted of an audio - visual display and a pamphlet on diabetes foot care . - pubmed
Methods : Retrospective chart review of 162 biopsy - proven MMP patients . - pubmed
Results : At presentation , 109 of 162 MMP patients ( 67.3 % ) had ocular involvement and 53 patients did not . - pubmed
Conclusions : Patients presenting with extraocular MMP are at risk for developing ocular MMP , and all MMP patients are at risk for developing secondary extraocular MMP locations , although the rates were low . - pubmed
Bovine spongiform encephalopathy ( BSE ) can be efficiently transmitted to pigs via intracerebral inoculation . - pubmed
A clear link has been established between the consumption of products of bovine origin contaminated with the BSE agent and the development of variant Creutzfeldt - Jakob disease in humans . - pubmed
Clinical characteristics of cognitive impairment in patients with Parkinson ' s disease and its related pattern in 18 F - FDG PET imaging . - pubmed
We recruited 168 PD patients and 100 age - matched healthy controls of similar education and gender distribution . - pubmed
In 53 PD patients who underwent 18 F - fluorodeoxyglucose ( 18 F - FDG ) PET imaging , correlations between Z - score values of the different cognitive domains and cerebral 18 F - FDG uptake were assessed using statistical parametric mapping ( SPM8 ) corrected for age and motor severity . - pubmed
A total of 23.2 % of PD patients were PD - MCI and 8.9 % were PD - D. - pubmed
In this report , we review poststroke psychiatric manifestations , and then present the case of a woman with schizophrenia whose thought disorder improved following a hemorrhagic stroke . - pubmed
Diagnostic paracentesis is indicated in all patients with a new onset of grade 2 or 3 ascites and in those admitted to hospital for any complication of cirrhosis . - pubmed
A careful selection of patients is also important to obtain the beneficial effects of transjugular intrahepatic portosystemic shunts in refractory ascites . - pubmed
Improve hip fracture outcome in the elderly patient ( iHOPE ): a study protocol for a pragmatic , multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia . - pubmed
INTRODUCTION : Hip fracture surgery is associated with high in - hospital and 30 - day mortality rates and serious adverse patient outcomes . - pubmed
Evidence from randomised controlled trials regarding effectiveness of spinal versus general anaesthesia on patient - centred outcomes after hip fracture surgery is sparse . - pubmed
In total , 1032 patients with hip fracture ( & gt;65 years ) will be randomised in an intended 1:1 allocation ratio to receive spinal anaesthesia ( n=516 ) or general anaesthesia ( n=516 ) . - pubmed
In pigs , Senecavirus A ( SVA ) causes a vesicular disease that is clinically indistinguishable from foot - and - mouth disease , vesicular stomatitis and swine vesicular disease . - pubmed
Anemic patients affected by BT suffer from iron overload , even in the absence of chronic blood transfusion , suggesting the presence of & gt;=1 erythroid factor with the ability to modulate iron metabolism and dietary iron absorption . - pubmed
In fact , genetic or pharmacological manipulations of iron metabolism or erythroid cell differentiation and survival have been shown to improve IE , iron overload , and anemia in animal models of BT . - pubmed
However , its clinical significance in COPD patients is poorly understood . - pubmed
Replacement of the Thiosugar of Auranofin with Iodide Enhances the Anticancer Potency in a Mouse Model of Ovarian Cancer . - pubmed
The present study shows that the iodido ( triethylphosphine ) gold ( I ) complex , ( Et 3 PAuI hereafter)-an AF analogue where the thiosugar ligand is simply replaced by one iodide ligand - manifests a solution chemistry resembling that of AF and exerts similar cytotoxic and proapoptotic effects on A2780 human ovarian cancer cells in vitro . - pubmed
Multi - stage surgery for a multiple - level spondylodiscitis caused by multidrug - resistant Mycobacterium avium complex . - pubmed
At 1 year after surgery , the patient suffered a proximal junctional failure secondary to a vertebral fracture that was solved with a proximal extension of the fusion using a percutaneous technique . - pubmed
The patient was successfully discharged with good pain control , satisfactory correction , no neurologic complications and an overall satisfactory outcome . - pubmed
ETHNOPHARMACOLOGICAL RELEVANCE : Atopic dermatitis ( AD ) , a disorder prevalent during childhood and adulthood , seriously affects the patient 's quality of life . - pubmed
One novelty in the present study is the use of human CL cases to predict the risk of leishmaniasis occurrence in response to anthropogenic , climatic and environmental factors at two different scales , in the Neotropical moist forest biome ( Amazonian basin and surrounding forest ecosystems ) and in the surrounding region of French Guiana . - pubmed
The predominantly identified human CL risk areas are those where the human impact on the environment is significant , associated with less contributory climatic and ecological factors . - pubmed
For both models this study highlights the importance of considering the anthropogenic drivers for disease risk assessment in human , although CL is mainly linked to the sylvatic and peri - urban cycle in Meso and South America . - pubmed
METHODS : We conducted a retrospective study of patients who underwent curative resection for non - small cell lung cancer between 1998 and 2011 . - pubmed
In multivariate analysis of the whole cohort , older patients , male gender , non - adenocarcinoma histology , more advanced pathological stage of lung cancer , interstitial pneumonia , and previous extrathoracic malignancies were associated with significantly worse prognosis . - pubmed
When propensity - score matched cohorts were compared , prognosis was significantly worse in patients with previous extrathoracic malignancies than those without ( 5 - year survival rates ; 75.3 % versus 82.7 % , p = 0.009 ) , although recurrence was not frequently seen ( 5 - year recurrence free rates ; 78.7 % versus 83.0 % , p = 0.491 ) . - pubmed
Proteomic Analysis of Dpy19l2 - Deficient Human Globozoospermia Reveals Multiple Molecular Defects . - pubmed
This multicenter study aims to develop and validate a novel and easy - to - access model for predicting the prognosis of patients with cirrhosis and acute GIB . - pubmed
METHODS : Patients with cirrhosis and acute GIB were enrolled and randomly divided into the training ( n = 865 ) and validation ( n = 817 ) cohorts . - pubmed
CONCLUSION : CAGIB score has a good predictive performance for prognosis of patients with cirrhosis and acute GIB . - pubmed
An 83 - year - old man suffered from cerebral infarction of the right middle cerebral artery territory . - pubmed
We intend to awaken an interest in the medication history of patients presenting with sudden diffuse alopecia areata . - pubmed
Epigallocatechin gallate ( EGCG ) , a major component of green tea , has been shown to possess a wide range of pharmacological properties , including anti - inflammation and anti - viral infection . - pubmed
Methods : A total of 301 patients with newly diagnosed thyrotoxicosis and without any anti - thyroid drug intervention were collected from the Department of Endocrinology and Metabolism , Peking University People 's Hospital from Jan. 2015 to Oct. 2018 . - pubmed
Among them , 241 patients were with Graves ' disease ( GD ) and 60 patients were with autoimmune thyroiditis ( AIT ) . - pubmed
The significant antibacterial activities of the TGQDs were found against a highly pathogenic bacterium ( Staphylococcus aureus ) and its antibiotic resistant strains ( vancomycin and methicillin resistant Staphylococcus aureus ) using growth curve analysis and determination of minimum inhibitory concentration ( MIC ) analysis . - pubmed
METHODS : A cross - sectional historical study was conducted including 219 patients aged 3 - 18 years who presented to a tertiary pediatric headache clinic in 2016 - 2017 . - pubmed
The prevalence of a positive history of colic was compared between children diagnosed with migraine or other primary headache types . - pubmed
Migraine headache was diagnosed in 170 patients ( 77.6 % ) and other types primary of headache ( 9 in total ) in 49 patients ( 22.3 % ) . - pubmed
Fifty - one patients had a history of infantile colic . - pubmed
They included 45 patients in the migraine group ( 26.5 % ) and 5 in the comparison groups ( 10.2 % ) ; the difference in the rate of colic was statistically significant ( P = .0196 ; OR 3.17 , 95 % CI 0.1.17 - 6.17 ) . - pubmed
Methods : We report a case of crystalluria in a patient treated empirically with intravenous acyclovir for possible viral meningitis . - pubmed
Toxicity of the synthesized NPs was tested on green gram ( Vigna radiata ) seed at various concentrations ( 20 - 100 % ) and germination was induced by NPs treated seeds . - pubmed
In addition , a xenograft tumor model was established in mice to evaluate the impact of miR-130a-3p on tumor growth in vivo . - pubmed
Overexpression of miR-130a-3p also promoted tumor growth in mice . - pubmed
METHODS : Ten RA subjects received 30 HBO2 treatments over 6 to 10 weeks . - pubmed
Serial rheumatologic evaluations ( ie , the Disease Activity Scale [ DAS28 ] , the Routine Assessment of Patient Index Data 3 , and the Pain and Sleep Quality Questionnaire ) were completed at baseline , throughout the course of the study , and at the 6 - month follow - up . - pubmed
CONCLUSIONS : Hyperbaric oxygen therapy is effective for joint pain in patients with RA based on data from multiple , validated clinical measures . - pubmed
Functions of tumor - associated macrophages and macrophages residing in remote anatomical niches in Ehrlich carcinoma bearing mice . - pubmed
MATERIALS AND METHODS : Ehrlich carcinoma was transplanted intramuscularly to Balb / c male mice . - pubmed
However , we have limited methods to evaluate ROS in tumor tissues and little knowledge on ROS metabolism across human cancers . - pubmed
Conclusion : Our study proposes a new method in evaluating ROS status and offers comprehensive understanding on ROS metabolic equilibrium in human cancers , which provide practical implications for clinical management . - pubmed
Innovations in early stroke detection and individualized patient selection for reperfusion therapies have equipped the emergency medicine clinician with more opportunities to help stroke patients and minimize the impact of this disease . - pubmed
Methods : From March 2016 to January 2020 , 25 patients with diabetic foot wounds were admitted to the First Affiliated Hospital of Air Force Medical University , including 18 males and 7 females , with age of 40 to 70 years . - pubmed
Two weeks after the suturing operation , the healing grade of the foot wound of patients was observed , and the serious complications such as recurrence of ulcer wound and gangrene on the foot , scar condition of the wound were observed during follow - up . - pubmed
Results : Two weeks after the suturing operation , the wounds of 23 patients were healed with grade A. - pubmed
Soft tissue infection ulcer relapsed in 2 patients during the stretch period . - pubmed
During the follow - up of 3 to 36 months , 23 patients had linear scar left on the stretch wounds , and the skin elasticity , color , sensation was similar to the surrounding normal tissue , and the limb mobility was good , and 2 patients had obvious scar hyperplasia . - pubmed
One patient had recurrence of diabetic foot and serious vascular occlusion and gangrene in the affected limb at follow - up of 10 months , which was treated with amputation of the lower leg . - pubmed
RESULTS : Overall , 3606 ( 66 % ) and 987 ( 18 % ) patients had LS < 10 and > 15 kPa , respectively , while cACLD was histologically confirmed in 1772 ( 31 % ) patients . - pubmed
Among 2260 patients with critical illness or injury receiving HEMS , compared with 315 patients with critical illness or injury receiving GEMS , adjusted cumulative 1 - year mortality was 25.1 % ( 95 % CI , 23.5%-26.7 % ) vs 27.1 % ( 95 % CI , 22.0%-32.1 % ) . - pubmed
Case 1 : A 51 - year - old man with advanced gastric cancer and peritoneal metastasis was referred to our hospital . - pubmed
Case 2 : A 75 - year - old woman with recurrence of peritoneally disseminated gastric cancer received third - line chemotherapy with nivolumab . - pubmed
Background : There are limited psychometrically sound measures to assess higher level balance in individuals with incomplete spinal cord injury ( iSCI ) . - pubmed
Methods : Twelve participants ( 11 male , 1 female ) 32 to 73 years old with chronic motor iSCI , American Spinal Injury Association Impairment Scale C ( n = 2 ) or D ( n = 10 ) , were included . - pubmed
A 22 - year - old man with a ventriculoatrial shunt was admitted to hospital for investigation of headache , nausea and vomiting . - pubmed
[ Incidence of antibodies to RS virus in children with acute respiratory diseases ] . - pubmed
The influence of D - Penicillamine on protein synthesis in synovial fluid cells was investigated in 5 patients suffering from rheumatoid arthritis . - pubmed
Low serum triiodothyronine in patients with anorexia nervosa . - pubmed
Patients with anorexia nervosa can demonstrate clinical and/or laboratory findings suggestive of reduced thyroid hormone secretion . - pubmed
The extremely low serum levels of T3 in these patients with anorexia nervosa suggest that peripheral conversion of T4 to T3 is impaired during chronic starvation . - pubmed
The skin - window inflammatory cell response was studied in 64 adult patients with various malignant neoplasms before initiation of chemotherapy and was repeated when a neutrophil level of 2500 cells / mm3 or less occurred . - pubmed
Of the 21 neutropenic patients , 15 had an abnormal neutrophil cell response and nine had an abnormal mononuclear cell response . - pubmed
Of the nine patients who had infection , eight had an abnormal mononuclear cell response and seven of the eight had a concomitant abnormal neutrophil response . - pubmed
The Rebuck skin window may be a practical clinical test to evaluate the risk for infection in neutropenic patients receiving cancer chemotherapy . - pubmed
We have carried out spectrofluorometric determinations of numerous substances such as drugs , chemicals and plants in order to find out whether there is a correlation between fluorescence data and photosensitization of the skin . - pubmed
Although caution is required in extrapolation of in vitro data to the in vivo state , these findings suggest rat seminiferous tubules may be incapable of de novo testosterone biosynthesis and that this lack of synthetic ability may be due to a deficiency of CSCCE . - pubmed
A patient is 18 years old ; he presents Peters ' anomaly , microcornea , the persisting of papillar membrana , congenital specifying lens for both eyes and atypical iridic coloboma for the right eye . - pubmed
Synergistic effect of romurtide with ampicillin against pneumococcal pneumonia in mice . - pubmed
In contrast , the combination treatment of romurtide with ABPC successfully prevented most of the mice from the purulent pneumonia : the initial infiltration of resident alveolar macrophages and subsequent accumulation of macrophages were observed in the pneumonic foci . - pubmed
In accordance with the occurrence of these cellular responses in the lungs , pneumococci were successfully eliminated from the lungs in mice treated with romurtide in combination with ABPC . - pubmed
Thus , romurtide was suggested to promote recovery of the mice with pneumococcal pneumonia by activating resident and accumulated macrophages in the pneumonic foci to eliminate pneumococci from the lung . - pubmed
Up to now , the best treatment for patients with acute myelogenous leukemia ( AML ) is the induction of bone marrow hypoplasia by ablative combined chemotherapy ; the prototype of these schedules is the so - called 7 + 3 ( seven days of continuous infusion of cytarabine and three days of one - hour infusion of any anthracycline ) ; these schedules require the support of both platelet transfusions and antibiotics . - pubmed
Here we analyze the results of the treatment of 76 adult patients with AML ; 43 were treated with the classical 7 + 3 schedule , whereas 33 were treated with a combination of chemotherapy used in non - ablative doses ( TADOP : thioguanine , arabinosyl - citosine , doxorrubicin , vincristine and prednisone ) . - pubmed
When Brucella melitensis strain Rev 1 vaccine ( Rev 1 ) is administered by the standard method ( 1 - 2 x 10(9 ) viable bacteria injected subcutaneously ) , it may induce long - lasting serological responses and/or cause abortion in pregnant animals . - pubmed
Treatment with ligno - paraffin increased the skin surface temperature 8.9 degrees C ; the temperature in the joint cavity was increased 3.5 degrees C. CONCLUSION : The use of short - wave diathermy and superficial heat packs in the treatment of patients with arthritis may potentially cause harm by increasing intraarticular temperature . - pubmed
This may have major implications regarding treatment policy for patients with arthritis . - pubmed
The murine skin multistage carcinogenesis model was used to characterize the co - promoting and tumor progressing activities of i.p . - pubmed
C57BL / 6 mice initiated with DMBA developed few papillomas ( 0.2 paps / mouse ) after 19 weeks of TPA promotion . - pubmed
Investigation of these possibilities in culture may provide insight into neuropathologic mechanisms operative in the fetal alcohol syndrome or alcohol - associated peripheral neuropathy in humans . - pubmed
Transient chimaerism occurred in half of the cases and was accompanied by the temporary appearance of the Philadelphia chromosome in one patient with chronic myeloid leukaemia without subsequent relapse . - pubmed
Dose - dependent modifications of cellular glutathione by NaOCN and organic isocyanates were observed in human HT29 colon tumor cells , rat HTC hepatoma cells , and rat hepatocytes . - pubmed
Does adjuvant radiotherapy have a role in the postmastectomy management of patients with operable breast cancer -- revisited . - pubmed
Routine " adjunctive postmastectomy radiotherapy for all patients with operable breast cancer obviously is not indicated , but there appear to be groups of patients who benefit from radiotherapy , both from the standpoint of disease - free survival and improved quality of life , and . - pubmed
In response to the posed question , while this remains a controversial issue , there appears to be a role for selective adjunctive postmastectomy radiotherapy in specific subsets of patients , and physicians administering adjunctive breast cancer therapy with sweeping applications of chemotherapy or anti - hormones alone do not appear to be offering their patients optimal therapy . - pubmed
51 patients were not examined for tuberculosis ( tuberculin test , chest x - ray , sputum investigation for tubercle bacilli , phthisiologist 's consultation , etc . ) - pubmed
Comparison of the metabolic effects of long - term treatment with pindolol or atenolol by hypertensive patients . - pubmed
[ Induction of chemiluminescence of human granulocytes by monocyte factors from patients with chronic polyarthritis and arthrosis ] . - pubmed
The supernatant of peripheral blood monocytes , cultured with autologous sera from patients with rheumatoid arthritis , stimulates healthy human granulocytes to significantly elevated chemiluminescence ( p = 0.05 ) compared with supernatants of monocytes from osteoarthritic patients or healthy volunteers . - pubmed
Louvain rat immunocytomas . - pubmed
Cell - mediated immunity in uremic patients prior to and after 6 months ' treatment with continuous ambulatory peritoneal dialysis . - pubmed
The number of circulating T - lymphocytes and their functional activity were studied in a group of 14 uremic patients prior to and after 6 to 9 months of treatment with continuous ambulatory peritoneal dialysis ( CAPD ) . - pubmed
After CAPD a clear improvement in functional activity of the T cells was found in 4 of 10 patients with impaired GVHR . - pubmed
Migrating action potential complexes in a patient with secretory diarrhea . - pubmed
A 70 - year - old woman with secretory diarrhea was studied with a novel technique of recording small intestinal myoelectrical activity which allowed us to obtain long , uninterrupted records of slow waves and spikes at eight or more different intestinal levels simultaneously . - pubmed
This is the first report on MAPC activity in man and on the association of this myoelectrical pattern with secretory diarrhea in man . - pubmed
[ Polysaccharide containing fractions of leptospira and possibilities of their applications for generic and specific diagnosis of leptospiroses ] . - pubmed
[ Acute febrile mucocutaneous lymph node syndrome in children ] . - pubmed
166.-Mutants of Agrobacterium tumefaciens auxotrophic for adenine , methionine , or asparagine are less infectious than the wild - type strain B6 from which they were derived and show increased infectivity on pinto bean leaves when the specific compounds required for growth of the mutants are added to the infected leaf . - pubmed
[ Intracranial hemorrhages in children in computerized - tomographic image ] . - pubmed
Consequently , an analysis of the medical records of 110 patients with biopsy proven squamous carcinoma originating in the retromolar trigone , seen and treated entirely at The University of Texas M.D. - pubmed
Thirty - six patients developed a second primary cancer of which 29 were in the upper aerodigestive tract . - pubmed
[ Curative action of mezlocillin on experimental infections in mice ( author 's transl ) ] . - pubmed
The curative action of mezlocillin on 10 severe experimental infections in mice was determined and expressed as effective dose 50 ( ED50 ) . - pubmed
Infections due to Proteus mirabilis and Klebsiella pneumoniae were the least susceptible to mezlocillin . - pubmed
For strains of 3 species ( S. - pubmed
[ Studies on the mechanism of the development of bronchial asthma due to Candida albicans . - pubmed
Postoperative fever was the presenting symptom in 19 patients . - pubmed
Jaundice occurred in 19 patients after a mean latent period of 8 days . - pubmed
Sixteen patients had been previously exposed to enflurane or halothane , and the latent period from exposure to the onset of symptoms or jaundice was shortened in these patients . - pubmed
Due to the early nuclide excretion with an advanced secretion peak it is no longer acceptable to use a 2 - minute calculation interval for hydronephrotic kidneys in dogs . - pubmed
A 57 - year - old psoriatic man had severe , isolated pulmonic regurgitation , with intractable right sided failure . - pubmed
Prednisone is the recommended treatment for patients with complete facial paralysis ; occasionally , selected patients may require surgical decompression . - pubmed
Hyperresponsiveness of migraine patients to bromocriptine . - pubmed
Plasma concentrations of digoxin and quinidine were measured ; in three of the seven dogs ECG and physical signs of digitalis toxicity were evaluated . - pubmed
On the days that digoxin was administered without quinidine , none of the dogs vomited nor was anorectic ; the PQ - interval increased significantly ( P less than 0.01 ) between 0.01 and 0.03 s. When quinidine was added , vomiting and anorexia occurred but no further increases in the PQ - interval were seen . - pubmed
METHODS : Cases were obtained from Mohs - referred basal cell carcinoma patients . - pubmed
Caffeine consumption was higher in the cancer patients . - pubmed
Electrophysiological evaluation of moricizine in patients with sustained ventricular tachyarrhythmias : low efficacy and high incidence of proarrhythmia . - pubmed
In patients with history of sustained ventricular tachycarrhythmias , the efficacy and safety of moricizine have not been systematically evaluated by electrophysiological studies . - pubmed
The study population comprised of 31 patients with clinically sustained ventricular tachyarrhythmia . - pubmed
The underlying heart disease was coronary in 25 patients , cardiomyopathy in 5 patients , and none in 1 patient . - pubmed
During the baseline drug - free electrophysiological testing , sustained ventricular tachycardia was inducible in 27 patients , ventricular fibrillation in 1 patient , and reproducible , nonsustained ventricular tachycardia ( 15 - 25 sec ) in 3 patients . - pubmed
Six patients developed ventricular proarrhythmia within the first 4 days . - pubmed
Proarrhythmia required multiple cardioversions in three patients , was not associated with QT prolongation , and spontaneously resolved 6 - 24 hours after withdrawal of moricizine . - pubmed
Four noninducible patients , two patients with inducible but slowed VT and one patient who had refused further testing were discharged on moricizine.(ABSTRACT TRUNCATED AT 250 WORDS ) - pubmed
The differential capacity of glucocorticoids and progestins to alter chromatin structure and induce gene expression in human breast cancer cells . - pubmed
Reactivity of neuroborreliosis patients ( Lyme disease ) to cardiolipin and gangliosides . - pubmed
Reimplantation or allotransplantation of the immature porcine left lower lobe results in long - term functional dynamic airway obstruction that is associated with abnormally small distal airways . - pubmed
METHODS : Seventy - six eyes in 41 patients were treated for acute retinopathy of prematurity from January 1991 to April 1994 . - pubmed
The sequences show similarity to several bacterial antibiotic resistance proteins , further supporting a role in detoxification and possibly Parkinson ' s disease . - pubmed
Glycated proteins as indices of glycaemic control in diabetic patients with chronic renal failure . - pubmed
Twenty uraemic diabetic patients took part in the study , including 5 patients managed conservatively , 6 on CAPD , 3 on haemodialysis , and 6 renal transplant recipients . - pubmed
Results were compared with those from 15 diabetic subjects with normal renal function . - pubmed
Fructosamine correlated significantly with mean blood glucose concentrations measured over the previous week in patients with normal renal function ( r = 0.75 ; p = 0.001 ) , but not in patients with chronic renal failure ( r = -0.1 ; p = 0.71 ) . - pubmed
The use of fructosamine can not be recommended as an index of glycaemic control in uraemic patients . - pubmed
The authors describe a case of a patient suffering from Wegener ' s disease with endobronchial manifestations which progressively developed tracheal stenosis which was not accessible to the usual immunodepressive therapy . - pubmed
A 2 - year - old child fell on a toothbrush , sustaining a pharyngeal injury . - pubmed
Oxidative organ damage in a rat model of thermal injury : the effect of cyclosporin A. - pubmed
Animal models of thermal trauma implicate oxygen radicals as a causative agent in local wound response , development of burn shock and distant organ injury . - pubmed
This study aimed to assess the role of neutrophils in the early and late phases of burn injury in rats with second - degree skin burn . - pubmed
Any patient with TYPE I SSEP changes had a new postoperative neurological deficit . - pubmed
In patients with end - stage lung disease , lung transplantation can be considered the only possibility of increasing pulmonary functional capacity . - pubmed
Selenate- and selenomethionine - induced leukopenia in ICR female mice . - pubmed
The leukopenia was more extensive and of a greater duration for selenomethionine - treated mice . - pubmed
OBJECTIVE : To describe the presence of crystalline opacities located at the level of the inner retina in patients with chronic retinal detachment . - pubmed
METHODS : We reviewed the clinical records , fundus photographs , and fluorescein angiograms of patients with superficial retinal crystals in the presence of a chronic retinal detachment . - pubmed
RESULTS : Eleven eyes in 11 patients with chronic retinal detachment were found to have these peculiar crystalline opacities on the inner retinal surface . - pubmed
The purpose of this study was to determine whether obese Zucker rats responded behaviorally and metabolically to intracerebroventricularly ( i.c.v . ) - pubmed
We found that both lean and obese Zucker rats had similar body weight and food intake responses when administered a single i.c.v . - pubmed
A decision analysis of the effect of avoiding axillary lymph node dissection in low risk women with invasive breast carcinoma . - pubmed
BACKGROUND : Evidence that avoiding axillary lymph node dissection ( AxD ) strikes an appropriate balance between morbidity and recurrence risk in patients with invasive breast carcinoma generally is anecdotal and without a formally quantified basis . - pubmed
METHODS : To derive quantitative estimates of the effect of avoiding AxD on 5 - year DFS , the authors examined outcomes for women undergoing 2 treatment scenarios : AxD or no AxD with adjuvant therapy decisions based on risk factors in the primary tumor . - pubmed
Eligible patients belonged to 2 lymph node metastases risk groups : low ( patients without palpable lymph nodes and lymphatic or vascular invasion [ LVI ] negative tumors & lt ; or = 0.5 cm in greatest dimension ) and moderate ( patients with mammographically detected , LVI negative tumors , between 0.6 - 2.0 cm in greatest dimension or patients with palpable LVI negative tumors between 0.6 - 1.0 cm in greatest dimension with nonpalpable lymph nodes ) . - pubmed
RESULTS : Patients in the low risk group had a 5 % risk of lymph node metastases . - pubmed
Patients in the moderate risk group had a 10 % risk of lymph node metastases . - pubmed
Eliminating AxD and treating only those women with Grade 3 tumors & gt ; 1 cm in greatest dimension with chemotherapy and/or tamoxifen resulted in a 1.8 % decrease in the 5 - year DFS rate . - pubmed
CONCLUSIONS : In patients with a low risk of lymph node metastases , it was estimated that eliminating AxD may result in only minimal changes in the estimated 5 - year DFS rate . - pubmed
In search of genetic factors causing elevated levels of total homocysteine in plasma ( tHcy ) , we investigated a cohort of consecutively identified , unrelated thrombosis patients ( n = 28 ) having intermediate or severe hyperhomocysteinemia ( 30 micromol / l<tHcy & lt ; or = 100 micromol / l , and tHcy & gt ; 100 micromol / l , respectively ) . - pubmed
Coxsackievirus B3 ( CVB3 ) is a common human pathogen that has been associated with serious diseases including myocarditis and pancreatitis . - pubmed
To better understand the effect of cytotoxic T - lymphocyte ( CTL ) responses in controlling CVB3 infection , we have inserted well - characterized CTL epitopes into the CVB3 genome . - pubmed
In this study , we cloned major histocompatibility complex class I - restricted CTL epitopes from lymphocytic choriomeningitis virus ( LCMV ) into recombinant CVB3 ( rCVB3 ) . - pubmed
rCVB3 replicated to high titers in vivo and caused severe pancreatitis but minimal myocarditis . - pubmed
In contrast , rCVB3 infection of LCMV - immune mice resulted in direct ex vivo cytotoxic activity against target cells coated with the epitope peptide , demonstrating that the rCVB3 - encoded LCMV - specific epitope was expressed and presented in vivo . - pubmed
Oxaceprol , an atypical inhibitor of inflammation , reduces leukocyte adherence in mouse antigen - induced arthritis . - pubmed
Since the exact mechanism of action remains unclear , the aim of our study was to investigate the leukocyte - endothelial cell interactions in oxaceprol - treated mice with antigen - induced arthritis ( AiA ) using intravital microscopy . - pubmed
In our study , Balb / c mice were allocated to 4 groups ( n 7 , 8 , 8 , 8) : 2 control groups with saline or oxaceprol and 2 groups of arthritic animals which received saline or oxaceprol ( 100 mg / kg twice a day intraperitoneally ) . - pubmed
With an estimated 3.9 million people infected nationwide , combined with the observation that , for over 50 % of all cases of HCV infection , a route of infection is unknown , HCV will continue to be a major cause of infectious disease related morbidity and mortality for years to come . - pubmed
A case of envenomation caused by the Nemalecium lighti is described . - pubmed
Curcumin exerts multiple suppressive effects on human breast carcinoma cells . - pubmed
In our study , we present experimental evidence suggesting that curcumin exerts multiple different suppressive effects on human breast carcinoma cells in vitro . - pubmed
Many endoscopy staff nurses become overwhelmed by the complexity of patient management and the realm of equipment necessary in providing endoscopic therapy for patients with biliary and pancreatic disease . - pubmed
Genetic regulation of malaria infection in humans . - pubmed
[ Assessment of efficacy and tolerability of mirtazapine treatment of patients with depression ] . - pubmed
The paper presents results of the study on the efficacy and tolerability of mirtazapine treatment of patients with depression . - pubmed
65 out- and in - patients with diagnosis of depression was included . - pubmed
OBJECTIVE : To describe the use of neuromuscular blocking agents ( NMBA ) in critically ill children . - pubmed
MAIN RESULTS : NMBAs were used for either short - term ( & lt;6 hrs ) or long - term neuromuscular blockade in 6%-9 % of patient ICU days and for long - term blockade in 14%-16 % of ventilatory support days . - pubmed
Myopathy after long - term use of NMBA was seen in only 1 patient ( 0.4 % ) . - pubmed
CONCLUSIONS : Use of NMBA is more common in critically ill children than in reported studies of critically ill adults . - pubmed
Use of NMBA in critically ill children is associated with high severity of illness and mortality rates . - pubmed
[ On the problem of occupational Coxiella burnetii infections in human subjects ] . - pubmed
The distribution of Staphylococcus aureus in hospital infections and epidemics related to special phage - types . - pubmed
Suprarenal stent grafting , recently modified from conventional infrarenal stent grafting , is a technique for the purpose of treating patients with inappropriate aneurysm necks . - pubmed
HIV and STD risk behavior among 18- to 25 - year - old men released from U.S. prisons : provider perspectives . - pubmed
It might be associated with considerable improved survival rate for liver failure patients . - pubmed
Retinoic acid induces growth arrest and differentiation in B16 mouse melanoma cells . - pubmed
Eighteen patients suffering of retinoblastoma during three years period ( 1999 - 2001 ) were treated in two departments of ophthalmology in the Czech Republic . - pubmed
We conclude that intracranial chondroma should be included in the differential diagnosis of a calcified mass for the patients who had had a compound , depressed skull fracture along the suture line , especially in cases of dural laceration by the fragmented bone . - pubmed
Reduced D - serine to total serine ratio in the cerebrospinal fluid of drug naive schizophrenic patients . - pubmed
METHODS : Liver samples of 12 patients undergoing autopsy , liver transplantation , or liver tumor resection were investigated . - pubmed
Sections & gt;1 cm(2 ) and stained by Sirius red were used for the reference staging of liver fibrosis in each patient according to the METAVIR scoring system . - pubmed
Objective B wave analysis in 55 patients with non - communicating and communicating hydrocephalus . - pubmed
OBJECT : To determine the relation between the percentage of B waves and outcome in patients with hydrocephalus , and also the diurnal variation of B waves . - pubmed
METHODS : ICP and patient behaviour were recorded overnight ( 17 to 26 hours ) in 29 patients with non - communicating hydrocephalus and 26 with NPH . - pubmed
The percentage of B waves was the same during sleep and wakefulness , and patients with NPH had the same proportion of B waves as the non - communicating patients . - pubmed
CONCLUSIONS : B waves are commonly observed in patients with both communicating and non - communicating hydrocephalus , but are only weakly related to the degree of postsurgical improvement . - pubmed
Preoperatively a total of 22 tubes were inserted in 13 patients to overcome urinary obstruction . - pubmed
A total of 24 transurethral prostatic tumor resections were performed in 11 patients . - pubmed
[ Combined effect of micafangin and itraconazole on severe aspergillosis of the bilateral pleural cavities in a patient with Wegener ' s granulomatosis ] . - pubmed
Here we report that combined use of two antifungal agents ( micafangin and itraconazole ) was effective against severe aspergillosis of the bilateral pleural cavities in a 48 - year old male patient diagnosed with Wegener ' s granulomatosis . - pubmed
Aspergillus fumigatus then infected the bilateral pulmonary cavities through these fistulas . - pubmed
This patient was treated with combined therapy of ITCZ and MCFG was given to this patient because of the risk of renal dysfunction associated with AMPH - B. - pubmed
RESULTS : Although similar with regard to age and sex , patients with diabetes more often had pre - existing cardiovascular and renal disease and heart failure as the cause of acute dyspnoea compared with patients without diabetes . - pubmed
In addition , medical and economic outcomes were worse in patients with diabetes . - pubmed
Laparoscopic cecostomy button placement for the management of fecal incontinence in children with Hirschsprung ' s disease and anorectal anomalies . - pubmed
BACKGROUND : Antegrade colonic enemas offer a surgical solution for many children with chronic constipation and encopresis associated with Hirschsprung ' s disease and anorectal malformations . - pubmed
METHODS : Charts of children with encopresis who underwent LCBP between 1999 and 2001 were reviewed . - pubmed
Four patients had anorectal malformations , and three patients had Hirschsprung ' s disease . - pubmed
For all the patients , LCBP was accomplished without any intraoperative complications . - pubmed
Episodes of soiling at night once or twice a week were observed with two children . - pubmed
Two patients had hypertrophic granulation tissue formation , which responded to topical therapy . - pubmed
CONCLUSION : To manage overflow incontinence of children with anorectal malformations and Hirschsprung ' s disease , LCBP is a technically straightforward , effective , and reversible method for the placement of a cecostomy button . - pubmed
Erythrocytes from twenty nine consecutive patients with rheumatoid arthritis ( 11 men , 18 women ) aged 54 years were obtained . - pubmed
Patients with rheumatoid arthritis were subdivided into two groups twice : with active disease ( 18 patients ) and in remission ( 11 patients ) , and secondly into patients receiving ( 21 subjects ) and not receiving ( 8 subjects ) non - steroidal anti - inflammatory drugs . - pubmed
It seems HSW balneum produce an antioxidant effect on erythrocyte status in patients with rheumatoid arthritis . - pubmed
Influence of disease stage on polyethylenimine - mediated plasmid DNA delivery in murine hepatitis . - pubmed
In order to determine the influence of hepatic disease - stage on polyethylenimine - mediated gene delivery , we investigated branched and linear polyethylenimine ( B - PEI , L - PEI)-mediated plasmid DNA delivery with time in murine hepatitis induced by a subcutaneous injection of tetrachloro carbon ( CCl ( 4 ) ) . - pubmed
Significant differences in gene expressions between CCl ( 4 )-treated mice and control mice vanished in most organs at the hepatitis subsidence stage ( 168 h after CCl ( 4 ) injection ) , indicating that the influence of hepatitis induced by CCl ( 4 ) was reversible with PEI - mediated gene delivery . - pubmed
Our findings demonstrated that murine hepatitis induced by CCl ( 4 ) could influence polyethylenimine - mediated plasmid DNA delivery according to the disease stage . - pubmed
Accordingly , the aim of this study was to investigate measures of insulin sensitivity , the metabolic syndrome , and sex hormones in patients with Klinefelter ' s syndrome and an age - matched control group . - pubmed
RESEARCH DESIGN AN METHODS : In a cross - sectional study , we examined 71 patients with Klinefelter ' s syndrome , of whom 35 received testosterone treatment , and 71 control subjects . - pubmed
We analyzed differences between patients with untreated Klinefelter ' s syndrome and control subjects and subsequently analyzed differences between testosterone - treated and untreated Klinefelter ' s syndrome patients . - pubmed
RESULTS : Of the patients with Klinefelter ' s syndrome , 44 % had metabolic syndrome ( according to National Cholesterol Education Program / Adult Treatment Panel III criteria ) compared with 10 % of control subjects . - pubmed
This review considers the animal and human evidence that lead exposure can produce a stark shift in immune functional capacity with a skewing predicted to elevate the risk of atopic and certain autoimmune diseases . - pubmed
METHODS : A clinical database and a severity scale was created to evaluate 45 patients diagnosed with Niemann - Pick type C in the last 28 years in Spain . - pubmed
Splenomegaly was present in 28 patients ( 93 % ) with a wide range of age at detection . - pubmed
Diagnosis was made before the onset of neurological signs in patients with the severe infantile form , at the time of onset of cerebellar signs in the late infantile form and complete ophthalmoplegia in late onset forms . - pubmed
CONCLUSIONS : In our series , splenomegaly is present in 96 % of patients , even in late onset forms during the first years of life . - pubmed
Clumsiness in children with otherwise normal motor development precedes the onset of ataxia by 2 - 4 years in Niemann Pick type C. - pubmed
PATIENT(S ): Seventy - three women with menorrhagia . - pubmed
The remaining five women requested the procedure be stopped because of pain . - pubmed
Significantly fewer women in the outpatient group experienced nausea ( 13 % versus 65 % in the daycase group ) or vomiting ( 0 versus 24 % in the daycase group ) , or required postoperative antiemetics ( 0 versus 56 % in the daycase group ) . - pubmed
Differential responses to anxiogenic drugs in a mouse model of panic disorder as revealed by Fos immunocytochemistry in specific areas of the fear circuitry . - pubmed
Sensitivity to pharmacological challenges has been reported in patients with panic disorder . - pubmed
Identification of Phytophthora sojae genes upregulated during the early stage of soybean infection . - pubmed
sojae genes that are differentially expressed in the early stage of Glycine max ( soybean ) infection . - pubmed
This report presents a natural history of a patient with low grade astrocytoma . - pubmed
The described patient with low - grade astrocytoma lived without any oncological treatment eight years and four months from the time when diagnosis was made until intracranial herniation . - pubmed
The natural history of disease in presented patient indicated that rational therapeutic strategy , for low - grade astrocytoma with epilepsy only , would be deferral of surgery until the time of manifestation of neurological or radiological deterioration . - pubmed
CASE - REPORT : A 34 - year - old patient presented with intraoral ulcerating , necrotizing inflammations of the palate and the gingiva . - pubmed
The patient died of cardiac decompensation three months after diagnosis . - pubmed
Behaviorally , 2 microL and 8 microL ZG - treated mice and those given multiple injections of 2 microL ZG performed as well as controls , whereas those given 50 microL were hyposmic but not anosmic . - pubmed
ZS - treated mice performed more poorly , and those injected with 50 microL were anosmic for the first 8 to 10 test days . - pubmed
Leuprorelin acetate every-3 - months depot versus cyclophosphamide , methotrexate , and fluorouracil as adjuvant treatment in premenopausal patients with node - positive breast cancer : the TABLE study . - pubmed
RESULTS : With a median follow - up of 5.8 years , recurrence - free survival was similar for patients treated with LAD-3 M or CMF ( hazard ratio [ HR ] , 1.19 ; 95 % CI , 0.94 to 1.51 ; P = .15 ) . - pubmed
The purpose of this study was to analyze the incidence and laterality of astigmatism in children with unilateral coronal synostosis . - pubmed
METHODS : We retrospectively reviewed the charts of 39 consecutive patients with unilateral coronal synostosis . - pubmed
Recorded data included the following : patient demographics , visual acuity , cycloplegic refraction , ocular motility , procedures for craniofacial and strabismus correction , and presence and treatment of amblyopia at each visit . - pubmed
RESULTS : Twenty - one of 39 patients ( 54 % ) had 1.00 D or more astigmatism in at least one eye at their last recorded refraction . - pubmed
Fifteen of the 39 studied ( 38 % ) had amblyopia and , in 12 of these 15 patients ( 80 % ) , the amblyopic eye was contralateral to the synostosis . - pubmed
Nineteen of 39 patients ( 49 % ) had greater ipsilateral fundus excyclotorsion , whereas only 1 of 39 ( 3 % ) had greater contralateral excyclotorsion . - pubmed
CONCLUSIONS : Patients with unilateral coronal synostosis are at risk for developing a greater degree of astigmatism in the eye contralateral to the synostosis . - pubmed
Ocular disturbances in the contralateral eye , especially anisometropic amblyopia , must be considered when treating patients with this type of craniosynostosis . - pubmed
We examined ( 1 ) microstructural changes of white matter ( WM ) adjacent to supratentorial low grade tumors in children and ( 2 ) WM tracts of the affected hemisphere using diffusion tensor imaging ( DTI ) . - pubmed
MATERIALS AND METHODS : DTI was performed in 11 children with low grade tumors diagnosed by magnetic resonance imaging ( MRI ) . - pubmed
CONCLUSION : We found preserved microstructural integrity of WM adjacent to low grade tumors in children . - pubmed
PURPOSE : To review the assessment , diagnosis , and management of hyponatremia ( serum sodium & lt;135 mEq / L ) , the most common electrolyte disturbance as a result of dysregulation of water balance in hospitalized or institutionalized patients . - pubmed
CONCLUSIONS : A diagnosis of hyponatremia requires thorough investigation for underlying causes and prompt treatment to prevent poor patient outcomes . - pubmed
Among this class of agents , intravenous conivaptan hydrochloride , indicated for the treatment of euvolemic hyponatremia in hospitalized patients , is the first drug in class approved for use . - pubmed
IMPLICATIONS FOR PRACTICE : Elderly patients , and those with certain conditions such as heart failure , tuberculosis , cirrhosis , and head injury , may be at increased risk for hyponatremia . - pubmed
In hospitalized patients following surgery and the use of certain medications , hyponatremia is a common condition . - pubmed
Awareness of the limitations of conventional therapies and the availability of new treatment options for hyponatremia allows clinicians to optimize patient care . - pubmed
OBJECTIVE : To examine performance of transcranial motor - evoked potential ( TcMEP ) monitoring in patients undergoing surgery for cervical myelopathy and potential risk factors for false positive alerts . - pubmed
SUMMARY OF BACKGROUND DATA : Although use of TcMEP monitoring has been increasing and has been specifically recommended in patients with cervical myelopathy , rates and risk factors for false positive alerts have not been established . - pubmed
METHODS : Intraoperative neuromonitoring data for 52 consecutive patients undergoing surgery for cervical myelopathy were reviewed . - pubmed
No new postoperative neurologic deficits were observed in these patients . - pubmed
One patient with new postoperative weakness was correctly predicted by loss of TcMEP signals . - pubmed
CONCLUSION : In this series of cervical myelopathy patients , sensitivity and specificity of TcMEP for detection of clinically significant intraoperative cord injury were 100 % and 90 % , respectively . - pubmed
The success of warfarin treatment for coronary thrombosis in a young patient with acute coronary syndrome . - pubmed
Using the chemical mammary carcinogenesis model of human c - Ha - ras transgenic ( Tg ) rats , we confirmed that parity protected the mammary glands at the postinitiation phase of tumorigenesis . - pubmed
Although the incidence of 7,12 - dimethylbenz [ alpha ] anthracene - induced palpable tumors was reduced from 61.5 % in the AMV Tg rats to 28.5 % in the parous animals , the incidence of early neoplastic lesions in the parous rats was the same as that in the AMV rats . - pubmed
PATIENTS AND METHODS : 37 patients with clinically suspected NPH were included in the study . - pubmed
Analysis of neuronal cell death in the cerebral cortex of H - Tx rats with compensated hydrocephalus . - pubmed
METHODS : The cerebral cortices of 8 - week - old H - Tx rats with spontaneously arrested hydrocephalus ( hH - Tx ) and nonhydrocephalic H - Tx ( nH - Tx ) control rats were subjected to cDNA microarray analysis followed by canonical pathway analysis . - pubmed
OBJECTIVE : This experimental , repeated - measures , crossover design study with nursing home residents examined the efficacy of reflexology in individuals with mild - to - moderate stage dementia . - pubmed
SAMPLE : The sample included 21 nursing home residents with mild - to - moderate stage dementia randomly assigned to two groups . - pubmed
CONCLUSIONS : This study provides preliminary support for the efficacy of reflexology as a treatment of stress in nursing home residents with mild - to - moderate stage dementia . - pubmed
SCA3 : neurological features , pathogenesis and animal models . - pubmed
METHODS : 161 critically ill patients requiring dialysis for ARF were analyzed . - pubmed
Patient demographics , comorbid conditions , ARF etiology , mode of renal replacement therapy ( RRT ) , renal recovery , and survival were abstracted from medical chart . - pubmed
Splenic erythroblasts were obtained from mice during the acute disease caused by anemiainducing virus ( FVA ) . - pubmed
METHODS : We conducted a case - control study of esophageal cancer patients from two centers , comparing cases with lung metastases to controls without lung metastases . - pubmed
Among patients with lung metastases , 73.6 % ( 39 of 53 ) were ever smokers , versus 47.8 % ( 144 of 301 ) of patients without lung metastases [ P=0.001 ; summary odds ratio ( OR ) , 2.52 ; 95 % confidence interval ( 95 % CI ) , 1.17 - 5.45 ; stratified by histology ] . - pubmed
We report a patient with pulmonary embolism , dissection in the descending and abdominal aorta , and persistent left superior vena cava . - pubmed
The cancer resistance is transferable to other strains of mice by adoptive transfer of innate immune cells . - pubmed
Serologic response to hepatitis B vaccine with high dose and increasing number of injections in HIV infected adult patients . - pubmed
In this chapter , we describe techniques used to determine the efficiency of hepatocyte transplantation in animal models of liver disease . - pubmed
Protocols for the collection of bile in rats and mice are described , and we have also detailed the detection of green fluorescent protein ( GFP)-labelled human hepatocytes in immunodeficient mice in this chapter . - pubmed
PURPOSE : Describing the ophthalmic findings of an exudative vasculopathy called as Coats - like retinitis pigmentosa on three patients . - pubmed
RESULTS : We have identified 3 patients who have some typical clinical features of Coats - like retinitis pigmentosa ; peripheral serous retinal detachment , telangiectasia , prominent lipid deposition , pigmentary changes in peripheral retina , and loss of vision . - pubmed
None of the three patients had positive family history . - pubmed
All of the patients have had symptoms of nyctalopia , decreased central vision , and two of them have had constriction of visual field . - pubmed
All of the patients have had cataracts and two of them underwent cataract surgery . - pubmed
Fundus examination and fluorescein angiography of patients revealed typical retinitis pigmentosa with Coats - type changes in bilateral inferiotemporal quadrants . - pubmed
Aclidinium bromide provides long - acting bronchodilation in patients with COPD . - pubmed
A total of 464 patients with moderate to severe stable COPD were randomised to double - blind , once - daily treatment with aclidinium ( 25 , 50 , 100 , 200 , or 400microg ) , placebo , or open - label tiotropium ( 18microg ) for 4 weeks . - pubmed
METHOD : Thirty - three patients ( 17 with mild ID and 16 with moderate to severe ID ) discharged between 2006 and 2008 from a specialised inpatient unit in Canada for adults with ID and mental illness were studied . - pubmed
However , only patients with mild ID demonstrated improvements on the Global Assessment of Functioning . - pubmed
Important differences between Fontan patients and controls were seen in several vascular compartments : ( 1 ) Calf capacitance was lower ( median , 3.5 versus 5.5 mL/100 mL tissue ; P=0.005 ) , and resting venous pressure was higher ( 13.0 versus 10.5 mm Hg ; P=0.004 ) ; ( 2 ) higher leg arterial resistance was observed ( 32.1 versus 22.2 ; P=0.03 ) ; ( 3 ) microvascular filtration pressures and threshold for edema were elevated ; and ( 4 ) with head - up tilt testing , splanchnic flow was not reduced in Fontan patients versus controls ( fractional change , +4 % versus -32 % ; P=0.004 ) , and splanchnic arterial resistance did not increase as expected ( fractional change , +8 % versus +79 % ; P=0.003 ) . - pubmed
The results in 5 eyes of 5 patients with aphakic bullous keratopathy and lack of capsule support are reported . - pubmed
We speculate that these SNPs may compromise mammary cell function , which may have important implications in human health and breast disease . - pubmed
The Substance Abuse and Mental Health Services Administration ( SAMHSA ) in the US Department of Health and Human Services is uniquely positioned to help develop national mental health policies that promote mental health and prevent mental illnesses . - pubmed
Somatic mutations in single network components lead to changes in transport dynamics that may contribute to pathological modifications underlying several human diseases such as mental retardation . - pubmed
Oral probiotics : Lactobacillus sporogenes for prevention of necrotizing enterocolitis in very low - birth weight infants : a randomized , controlled trial . - pubmed
Lactobacillus sporogenes has not been used in the prevention of NEC in very low - birth weight infants yet . - pubmed
The objective of this study was to evaluate the efficacy of orally administered L sporogenes in reducing the incidence and severity of NEC in very low - birth weight ( VLBW ) infants . - pubmed
SUBJECTS / METHODS : A prospective , blinded , randomized controlled trial was conducted in preterm infants with a gestational age of & lt;33 weeks or birth weight of & lt;1500 g. VLBW infants who survived to start enteral feeding were randomized into two groups The infants in the study group were given L. - pubmed
We investigated the teratogenic agent phenytoin and extract of the immunostimulant Echinacea purpurea in the etiology of cleft palate associated with the proliferation and apoptosis of mouse embryonic palatal mesenchymal ( MEPM ) cells . - pubmed
The teratogenic effect of phenytoin on cleft palate is associated with the proliferation and apoptosis of MEPM cells , and E. - pubmed
PATIENTS : Six high - level rock climbers with SLAP lesions and degeneration of the long biceps tendon anchor or additional pulley lesions were surgically treated with primary tenodesis . - pubmed
We report isolation of Histoplasma capsulatum from the blood of an AIDS patient . - pubmed
Aging and antihypertensive medication - related complications in the chronic kidney disease patient . - pubmed
PURPOSE OF REVIEW : We have reviewed the recent literature to describe the potential medication errors and adverse drug events ( ADEs ) associated with antihypertensives among older adults with chronic kidney disease ( CKD ) . - pubmed
RECENT FINDINGS : Overall , few studies have been published describing ADEs in older adults with CKD . - pubmed
SUMMARY : Some of the most common ADEs associated with antihypertensive use in older adults with CKD include hyperkalemia , AKI , and orthostatic hypotension . - pubmed
Treatment of HEY xenograft - bearing mice with dasatinib plus paclitaxel inhibited tumor growth more than treatment with either agent alone ( average tumor volume per mouse , dasatinib + paclitaxel vs paclitaxel : 0.28 vs. 0.81 cm3 , difference = 0.53 cm3 , 95 % confidence interval [ CI ] = 0.44 to 0.62 cm3 , P = .014 ) ; dasatinib + paclitaxel vs. dasatinib : 0.28 vs. 0.55 cm3 , difference = 0.27 cm3 , 95 % CI = 0.21 to 0.33 cm3 , P = .035 ) . - pubmed
JPH203 was intravenously administered to produce significant growth inhibition against HT-29 tumors transplanted in nude mice . - pubmed
Microarray meta - analysis defines global angiogenesis - related gene expression signatures in human carcinomas . - pubmed
BACKGROUND : The correlation between the number of pathologic metastatic LNs in patients with esophageal squamous cell carcinoma ( ESCC ) after neoadjuvant chemoradiotherapy ( NACRT ) and surgical outcome has rarely been reported . - pubmed
METHODS : Eighty - eight patients with ESCC who underwent NACRT followed by surgery were evaluated . - pubmed
According to the number of metastatic LNs , the difference in the median survival was the largest between the groups when patients were divided into those with 2 and 3 metastatic LNs ( chi(2 ) : 13.694 , P & lt ; 0.001 ) . - pubmed
The purpose of this systematic review was to investigate the effects of therapeutic radiopharmaceuticals in patients with different types of advanced neuroendocrine tumour ( NETs ) . - pubmed
The severe toxicities for ( 177 ) Lu - DOTATATE included hepatic insufficiency in 0.6 % , myelodysplastic syndrome in 0.8 % and renal insufficiency in 0.4 % of patients in this study . - pubmed
Insufficient evidence suggested efficacy of ( 131 ) I - MIBG in adult NET patients , but the overall tumour response rate from ( 131 ) I - MIBG was 27 - 75 % for malignant neuroblastoma , paraganglioma or pheochromocytoma . - pubmed
Haematological toxicities were the main severe side - effects after ( 131 ) I - MIBG and 4 % of patients developed secondary malignancies in one study . - pubmed
The virus is associated with respiratory problems in pigs of all ages and is commonly isolated on farms with porcine respiratory disease complex ( PRDC ) . - pubmed
Due to virus - induced macrophage death early in infection , PRRSV hampers the innate defence against pathogens in the lungs . - pubmed
Similar results were obtained using inactivated PRRSV ( LV ) , showing that initial interaction of the virion with the cell is sufficient to reduce phagocytosis , and that no productive infection is required . - pubmed
We identified 47 patients with spina bifida ( median age at followup 26.8 years ) who underwent either enterocystoplasty or detrusorectomy between 1988 and 2004 . - pubmed
The relationships between genome wide association study - identified and replicated genetic variants associated with Alzheimer ' s disease ( AD ) risk and disease progression or therapeutic responses in AD patients are almost unexplored . - pubmed
We studied 59 patients with idiopathic dilated cardiomyopathy who had a potential clinical and echocardiographic follow - up period of & gt;12 years . - pubmed
Of the 59 patients , 38 died ( heart failure in 20 , sudden death in 11 , and other causes in 7 ) , 2 underwent transplantation , and 19 survived . - pubmed
Of the 1,000 patients , 82 were excluded owing to negative or interval appendectomy or advanced end - stage renal disease . - pubmed
Glucocorticoid - induced changes in gene expression of airway smooth muscle in patients with asthma . - pubmed
METHODS : Twelve steroid - free patients with atopic asthma were included in this double - blind intervention study . - pubmed
OBJECTIVE : To evaluate the association between severity of cerebral palsy ( CP ) and growth to 6 to 7 years of age among children with moderate to severe ( Mod / Sev ) hypoxic ischemic encephalopathy ( HIE ) . - pubmed
It was hypothesized that children with Mod / Sev CP would have poorer growth , lower cognitive scores , and increased rehospitalization rates compared with children with no CP ( No CP ) . - pubmed
METHODS : Among 115 of 122 surviving children followed in the hypothermia trial for neonatal HIE , growth parameters and neurodevelopmental status at 18 to 22 months and 6 to 7 years were available . - pubmed
The control group was consisted of patients who underwent arthroscopic surgery for other reasons than cartilage disorders . - pubmed
In the osteoarthritis group all patients had grade 4 primer degenerative osteoarthritis and were treated with total knee arthroplasty . - pubmed
This study proposes to establish data - driven criteria for the use of CXR as a diagnostic modality in the preoperative evaluation of patients with PE . - pubmed
METHODS : A total of 57 consecutive patients with ascites requiring a large volume paracentesis were studied . - pubmed
A 74 - year - old man presents with a left upper lobe lung adenocarcinoma , which demonstrated a wide base intimately with the aortic arch . - pubmed
Asymmetric dimethylarginine levels in patients with cutaneous anthrax : a laboratory analysis . - pubmed
The aim of the study was to investigate the serum ADMA levels in patients with CA . - pubmed
METHODS : A total of 35 serum samples of the patients with CA and 18 control sera were tested for ADMA levels using ADMA ELISA kit ( Immunodiagnostik AG , Bensheim , Germany ) . - pubmed
In addition , these data might suggest the higher ADMA levels in patients could be due to the perivascular inflammation and vasculitis in CA . - pubmed
[ Clinical features of rituximab plus chemotherapy as first - line treatment in patients with diffuse large B - cell lymphoma ] . - pubmed
OBJECTIVE : A prospective , multicenter and non - interventional prospective study was conducted to evaluate the clinical features of rituximab combined with chemotherapy ( R - Chemo ) as first - line treatment on newly diagnosed Chinese patients with diffuse large B - cell lymphoma ( DLBCL ) . - pubmed
ECOG performance statuses of 0 or 1 were observed in 91.1 % of patients , international prognostic index levels in the low - risk and low - middle - risk groups in 76.4 % of patients , the tumor diameters smaller than 7.5 cm in 69.0 % of patients . - pubmed
CONCLUSION : Non - interventional clinical trial of R - Chemo remains the standard first - line treatment for newly diagnosed patients with DLBCL in real clinical practice , which is consistent with international treatment recommendations for DLBCL patients . - pubmed
R - Chemo can provide the clinical evidence and benefit as the first - line standard treatment for Chinese patients with DLBCL . - pubmed
METHODS : Between November 2008 and December 2009 , 107 patients who were diagnosed as having lung cancer or strongly suspected of having lung cancer were enrolled . - pubmed
RESULTS : In 100 patients , the early ( 18 ) F - FDG PET scan resulted in upstaging of the tumor in ten ( 10 % ) and down - staging of the tumor in five ( 5 % ) compared to the conventional scan . - pubmed
The delayed phase of ( 18 ) F - FDG PET provided no additional information on staging for lung cancer patients . - pubmed
The remaining seven patients were diagnosed as not having lung cancer . - pubmed
CONCLUSION : This study confirmed that dual - time - point ( 18 ) F - FDG PET is useful for differential diagnosis between benign and malignant lesions , but has no major impact on staging and therapeutic management of patients with pathologically proven lung cancer . - pubmed
Most patients with CDI had negative blood cultures or grew Staphylococcus sp . - pubmed
The percentages of underweight , overweight and obese patients were ; 27.3 % , 18.2 % and 3.6 % , respectively pre - MMT , and 12.7 % , 18.2 % and 7.2 % , respectively after MMT . - pubmed
MATERIAL AND METHODS : A retrospective analysis was made of patients treated at the Department of Head and Neck Surgery in the Greater Poland Cancer Centre of the Poznan University of Medical Sciences in 2007 - 2012 for BCC of the head and neck region . - pubmed
RESULTS : In the study group of 312 tumors , recurrence after initial treatment in this Centre was diagnosed in 18 patients ( 9 % ) , whereas in patients who were previously operated elsewhere , recurrence was found in 22 cases ( 17 % ) . - pubmed
The nodular type was the most common BCC type in the study group and concerned 175 patients ( 56 % ) . - pubmed
CONCLUSIONS : The importance of preoperative biopsy to assess the histological type as a routine treatment of patients with BCC is essential . - pubmed
Increased risk of end - stage renal disease in patients with renal cell carcinoma : a 12 - year nationwide follow - up study . - pubmed
Osteoarthritis ( OA ) is a progressive joint disorder , which remains the leading cause of chronic disability in aged people . - pubmed
Circulating microRNAs in patients with non - alcoholic fatty liver disease . - pubmed
METHODS : Twenty patients with histologically proven NAFLD and 20 controls were included . - pubmed
RESULTS : Serum levels of miR-181d , miR-99a , miR-197 and miR-146b were significantly lower in biopsy - proven NAFLD patients than in the healthy controls . - pubmed
CONCLUSIONS : The study results indicate that sevoflurane , like propofol , induces coherent frontal alpha oscillations and slow oscillations in humans to sustain the anesthesia - induced unconscious state . - pubmed
Evaluation of an oral supplement containing Phyllanthus emblica fruit extracts , vitamin E , and carotenoids in vitiligo treatment . - pubmed
Phyllanthus emblica , vitamin E , and caroteinods are compounds showing antioxidative , anti - inflammatory , and repigmenting effects , whose role in vitiligo treatment has not been evaluated so far . - pubmed
Moreover , group B patients showed higher signs of inflammation ( p = 0.002 ) , a more rapid growth of the lesions ( p = 0.039 ) , a higher percentage of worsening disease ( p = 0.003 ) , and more erythema ( p = 0.059 ) , whereas group A patients showed a higher percentage of steady disease ( p = 0.065 ) . - pubmed
Our results suggest that the supplement with antioxidants in patients with vitiligo might represent a valuable instrument to increase the effectiveness of other vitiligo treatments . - pubmed
OBJECTIVE : The following report presents a case in which significant clozapine toxicity was demonstrated in a patient on established therapy , in the absence of identifiable risk factors . - pubmed
RESULTS : We describe a case of a 62 year old man whom developed life - threatening clozapine toxicity in the context of a severe lower respiratory infection . - pubmed
Unfortunately case management in health facilities is very poor ; health facilities are few and understaffed mainly with unskilled personnel who are overburdened by other illnesses such as malaria and HIV and the supply of praziquantel in health facilities is inadequate . - pubmed
An uncommon cause of allergic fungal sinusitis : Rhizopus oryzae . - pubmed
We report what we believe is the first case of allergic fungal rhinosinusitis ( AFRS ) caused by the fungus Rhizopus oryzae . - pubmed
Our patient was a 32 - year - old woman who presented with unilateral nasal polyps and chronic nasal dysfunction . - pubmed
Comparative analysis with the KiGGS data ( & gt;14,000 spot urines of children ; median UIC 117 microg / L ) revealed a comparable percentage & lt;EAR ( 33 % ) . - pubmed
Biomechanical and Macroscopic Evaluations of the Effects of 5 - Fluorouracil on Partially Divided Flexor Tendon Injuries in Rabbits . - pubmed
This study aims to develop a prognostic risk prediction model for the development of silicosis among workers exposed to silica dust in China . - pubmed
An analysis of the intervention effect of perioperative evidence - based nursing on orthopedic trauma patients ' vagal reflex . - pubmed
PATIENTS AND METHODS : Eighty - six patients were selected , who were hospitalized in orthopedics department of our hospital because of trauma from March , 2013 to March , 2014 . - pubmed
CONCLUSIONS : EBN could reduce the prevalence of vagal reflex to some extent on perioperative orthopedic trauma patients . - pubmed
It is usually a diffuse , low - grade astrocytoma ( WHO grade II ) , seen mainly in adults , with approximately 25 % of them involving children under the age of 15 . - pubmed
We report a 1 - year follow - up of a 55 - year - old female patient with bilateral WHO grade II thalamic astrocytoma . - pubmed
The primary aim was to compare postoperative radiographic outcomes between sexes among adolescent idiopathic scoliosis ( AIS ) patients . - pubmed
A total of 162 AIS patients ( 42 males and 120 females ) undergoing pedicle screw instrumentation and posterior fusion were included . - pubmed
Yet , in a significant number of patients the transfemoral access is not suitable due to peripheral vascular disease of the lower extremity . - pubmed
[ Prevalence of deep venous thrombosis in burn patients and its influencing factors ] . - pubmed
METHODS : Clinical data of 2 506 burn patients admitted to our ward from January 2009 to January 2014 , conforming to the study criteria , were retrospectively analyzed . - pubmed
Patients were divided into DVT group ( n=26 ) and non - DVT group ( n=2 480 ) according to whether or not DVT occurred during hospitalization . - pubmed
Metabolic bone disease is a common complication of PBC , affecting 14 % to 52 % of patients , depending on the duration and severity of liver disease . - pubmed
Additional large prospective , long - term studies in patients with PBC are needed to determine efficacy in improving bone density as well as reducing fracture risk . - pubmed
Sheep receiving nontransfected BMMSCs ( BMMSC ; n=6 ) displayed less infarct size limitation and percent LVEF improvement , whereas in placebo - treated animals ( n=6 ) , neither parameters changed over time . - pubmed
Classification of Extraovarian Implants in Patients With Ovarian Serous Borderline Tumors ( Tumors of Low Malignant Potential ) Based on Clinical Outcome . - pubmed
The classification of extraovarian disease into invasive and noninvasive implants predicts patient outcome in patients with high - stage ovarian serous borderline tumors ( tumors of low malignant potential ) . - pubmed
Peritoneal and/or lymph node implants from 181 patients with high - stage serous borderline tumors were evaluated independently by 3 pathologists for the following 8 morphologic features : micropapillary architecture ; glandular architecture ; nests of epithelial cells with surrounding retraction artifact set in densely fibrotic stroma ; low - power destructive tissue invasion ; single eosinophilic epithelial cells within desmoplastic stroma ; mitotic activity ; nuclear pleomorphism ; and nucleoli . - pubmed
Assessing patient outcomes and cost - effectiveness of nurse - led follow - up for women with breast cancer - have relevant and sensitive evaluation measures been used ? - pubmed
Challenges in the first seizure clinic for adult patients with epilepsy . - pubmed
AIMS : ( 1 ) To delineate the challenges in seizure diagnosis in the first seizure clinic setting for adult patients of a teaching hospital , and ( 2 ) quantify the diagnostic accuracy of the referral source and the yield of routine investigations , including blood tests , EEGs , and neuroimaging . - pubmed
RESULTS : In total , 219 patients were referred to the first seizure clinic . - pubmed
From the cohort , 38 ( 17 % ) patients presented with seizure mimickers ; the most common were reflex syncope ( 74 % ) and psychogenic non - epileptic seizures ( 16 % ) . - pubmed
From the remaining 181 patients presenting with seizures , only 110 ( 61 % ) of these patients were diagnosed with true first seizures , and 71 ( 39 % ) patients had evidence of previous seizures . - pubmed
In our true first seizure patients , the EEG demonstrated epileptiform discharges in 22 ( 21 % ) patients . - pubmed
Our data highlight the potential pitfalls and practical challenges in this process , as well as the need for these patients to be assessed in dedicated first seizure clinics . - pubmed
Finally , the trajectory of body weight changes was affected by irradiation , with lower body weights in irradiated than sham - irradiated mice , with the most profound effect 7days after training . - pubmed
These data indicate that whole body X ray irradiation of mice at 3 months of age causes persistent alterations in the fear response and activity levels in a novel environment , while the effects on body weight seem more transient . - pubmed
PATIENT CONCERNS : In Sep 2015 , a 59 - year - old female patient presented to our hospital , complaining of refractory low back pain , left sternoclavicular joint pain , and palmoplanar pustulosis ( PPP ) . - pubmed
In addition , RA had been diagnosed 10 years earlier in the patient , manifested as pain and swelling in bilateral hands and wrists , accompanied by morning stiffness , as well as positive serologic tests . - pubmed
Intersexual differences of heat shock response between two amphipods ( Eulimnogammarus verrucosus and Eulimnogammarus cyaneus ) in Lake Baikal . - pubmed
cyaneus females after heat shock and recovery compared to males , which was not found for E. - pubmed
Do bilateral and unilateral greater occipital nerve block effectiveness differ in chronic migraine patients ? - pubmed
We aimed to compare the effectiveness of bilateral and unilateral block application in chronic migraine patients and whether there were differences in their effectiveness retrospectively . - pubmed
In chronic migraine patients undergoing Greater occipital nerve ( GON ) block , mean number of days with pain per month before and after block , mean duration of pain in attacks ( in hours ) , and mean Visual Analog Scale ( VAS ) in attack and pain severity were recorded from files . - pubmed
METHODS : Sprague - Dawley rats were used to establish AP model by intraperitoneal injection of 20 % L - arginine ( 4 g / kg ) twice with an interval of 1 hour . - pubmed
Thrombophilia , elevated estrogenic states , and infections are the most common risk factors in patients who develop CVT . - pubmed
CASE : A 69 - year - old man with a right - sided odontogenic infection presented with fever , headache , opthalmoplegia , and periorbital swelling . - pubmed
Unfractionated or low molecular weight heparin may be safely used in CVT patients . - pubmed
MATERIALS AND METHODS : This retrospective study included 249 consecutive patients who underwent evaluation for normal pressure hydrocephalus . - pubmed
pestis ) has caused an alarming number of deaths throughout recorded human history , and novel prophylactics and therapeutics are necessary given its potential as a bioweapon . - pubmed
pestis 141 infection when administered prophylactically to Balb / c mice ( 100 mug intravenously ) . - pubmed
Enhanced antitumor activity of surface - modified iron oxide nanoparticles and an alpha - tocopherol derivative in a rat model of mammary gland carcinosarcoma . - pubmed
Wistar rats with Walker-256 carcinosarcoma ( a model of mammary gland carcinosarcoma ) received Toc-6 - Ac , magnetic nanoparticles , or their combination per os , and the antitumor activity of each treatment was determined in vivo . - pubmed
To investigate the comparative effects on the body weight , organ weight and lipid profile , the crude oil of Silybum marianum , edible sunflower oil and vegetable ghee were given to three groups of rabbits under study . - pubmed
METHODS : The effects of ADM _ 12 on nitroglycerin - induced hyperalgesia at the trigeminal level were investigated in male rats using the quantification of nocifensive behavior in the orofacial formalin test . - pubmed
RESULTS : In rats bearing nitroglycerin - induced hyperalgesia , ADM_12 showed an anti - hyperalgesic effect in the second phase of the orofacial formalin test . - pubmed
Patient - specific seizure detection in long - term EEG using signal - derived empirical mode decomposition ( EMD)-based dictionary approach . - pubmed
OBJECTIVE : The objective of the work described in this paper is the development of a computationally efficient methodology for patient - specific automatic seizure detection in long - term multi - channel EEG recordings . - pubmed
The renewed interest to this class of evoked potentials is due to unexplained differences in the results of cochlear implantation in the patients with the similar audiological data , etiology , age and the history of deafness as well as cochlear implant surgery in children of first years of life and the extended possibilities for speech processor programming . - pubmed
It is concluded that the longer duration of deafness and later age at implantation result in immature morphology and delayed peak latencies and that patients with shorter latencies and higher amplitudes have better speech perception . - pubmed
METHODS : Pre - planned analysis of the prospective multinational TAVeM database , performed on 2960 patients receiving mechanical ventilation for & gt;48 h , including 689 patients with VA - LRTI . - pubmed
RESULTS : Four hundred and four patients ( mean age 63 years , 298 men , ICU mortality 40 % ) were studied , 207 with VAT and 197 with VAP . - pubmed
We confirmed increases in insulin resistance , glucose tolerance , peripheral inflammation and dysarteriotony in PM2.5 - induced mice . - pubmed
BACKGROUND : Easily accessible biomarkers are needed for the early identification of individuals at risk of developing Alzheimer ' s disease ( AD ) in large population screening strategies . - pubmed
The mass production and consumption of medication for the treatment of infectious diseases in human and animals have led to the ubiquity of antibiotics in the environment . - pubmed
We studied the single and joint effects of microplastics ( 1 - mum and 10 - mum polystyrene particles , PS ) and roxithromycin ( ROX ) on Daphnia magna through the acute and sublethal toxicity tests . - pubmed
Blood - brain barrier dysfunction in canine epileptic seizures detected by dynamic contrast - enhanced magnetic resonance imaging . - pubmed
OBJECTIVE : Dogs with spontaneous or acquired epilepsy exhibit resemblance in etiology and disease course to humans , potentially offering a translational model of the human disease . - pubmed
To test the hypothesis that BBBD can be detected in dogs with naturally occurring seizures , we developed a linear dynamic contrast - enhanced magnetic resonance imaging ( DCE - MRI ) analysis algorithm that was validated in clinical cases of seizing dogs and experimental epileptic rats . - pubmed
METHODS : Forty - six dogs with naturally occurring seizures of different etiologies and 12 induced epilepsy rats were imaged using DCE - MRI . - pubmed
RESULTS : We found BBBD in 37 % of dogs with seizures . - pubmed
A significant difference was found between epileptic and control rats when BBBD scores were calculated for the piriform cortex at 48 hours and 1 month after status epilepticus . - pubmed
Mean BBBD score of the piriform lobe in idiopathic epilepsy ( IE ) dogs was significantly higher compared to control . - pubmed
SIGNIFICANCE : Detection of BBBD in dogs with naturally occurring epilepsy provides the ground for future studies for evaluation of novel treatment targeting the disrupted BBB . - pubmed
Under the optimal conditions , the yeast strain could yield 73.25 + - 2.3 g / L of EPS within 5 days at a flask level . - pubmed
The mutant DAG27 was more sensitive to radiation of UV light , high NaCl concentration , heat treatment , strong oxidation of H2O2 and desiccation than its wild type strain 13 - 2 , suggesting that the produced pullulan could play an important role in resistance of the yeast cells to various stresses . - pubmed
This was the first time to show that the yeast strain obtained from the desert could produce such high level pullulan and the produced pullulan had an obviously protective effect on its producer . - pubmed
Methods : We present three children of a family with progressive weakness , mild sensory loss , and absent tendon reflexes . - pubmed
Electrodiagnostic analyses displayed an axonal type of neuropathy in affected patients . - pubmed
Results : All affected individuals manifested identical clinical symptoms of motor and sensory impairments within the first three years of life , and nerve conduction study indicated the axonal degeneration . - pubmed
In this hemodynamic rounds discussion , we evaluated a patient with MS and PHT prior to the decision for mitral valvuloplasty . - pubmed
KEY POINTS : Symptoms in patients with mitral stenosis and pulmonary hypertension can not always be attributed to one pathology . - pubmed
Luteolin reduces adipose tissue macrophage inflammation and insulin resistance in postmenopausal obese mice . - pubmed
Previously , we showed that loss of ovarian function in mice fed high - fat diet exacerbated insulin resistance and adipose tissue inflammation . - pubmed
In the current study , we tested whether consumption of luteolin , an anti - inflammatory flavonoid , could mitigate adipose tissue inflammation and insulin resistance in obese ovariectomized mice . - pubmed
Results showed no difference in body weight or fat mass between mice fed HFD+L and those fed HFD . - pubmed
Human trichinellosis is a disease caused by nematode worms of the genus Trichinella . - pubmed
In Italy , as well as in most other European countries , notification of Trichinella infections in humans is mandatory ; however , no information is available on the number of cases occurring annually . - pubmed
INTRODUCTION : Ablation remains a modality of choice in select patients with Atrial fibrillation ( AF ) . - pubmed
Studies comparing the use of surgical or catheter ablation in patients with AF were included . - pubmed
RESULTS : Eight studies ( 744 patients ) reported a statistically significant difference in Arrhythmia recurrence rate between surgical and catheter - based ablation . - pubmed
This review surveys the research of power - based models of fatigue and recovery within the area of human performance . - pubmed
Purpose : The aim of this study was to compare the metabolic load between adaptive support ventilation ( ASV ) and pressure support ventilation ( PSV ) modes in critically ill patients . - pubmed
Methods : Sequential 20 min ventilation by PSV followed by 20 min ASV in critically ill patients was assessed . - pubmed
Results : Twenty - four patients with critical illness participated in the study . - pubmed
Birth weight and subsequent weight gain is of critical importance in the survival and performance of piglets on a commercial swine farm setting . - pubmed
Thus , providing a basis for the development of strategies aimed at improving weight gain in pigs . - pubmed
Bioresorbable scaffolds versus permanent sirolimus - eluting stents in patients with ST - Segment Elevation Myocardial Infarction : vascular healing outcomes from the MAGSTEMI trial . - pubmed
We report a 21 - year - old woman who presented with dorsoulnar wrist pain during palmar wrist flexion and soft tissue mass at the site of pain . - pubmed
Conservative treatment for 3 months failed to improve the patient 's pain levels . - pubmed
METHOD : Patients with HCC undergoing rTACE at six Australian tertiary centers from 2009 to 2014 were included . - pubmed
RESULTS : Total of 292 consecutive patients underwent rTACE with mainly Child Pugh A cirrhosis ( 61 % ) and BCLC stage A ( 57 % ) disease . - pubmed
Non - invasive brain stimulation in Stroke patients ( NIBS ): A prospective randomized open blinded end - point ( PROBE ) feasibility trial using transcranial direct current stimulation ( tDCS ) in post - stroke hemispatial neglect . - pubmed
Up to 80 % of people who experience a right - hemisphere stroke suffer from hemispatial neglect . - pubmed
We carried out a clinical feasibility trial of transcranial direct current stimulation ( tDCS ) and a behavioural rehabilitation programme , alone or in combination , in patients with neglect . - pubmed
RESULTS : Twelve prospective studies were assessed , including 536 patients with CRCLMs ( n = 1335 ) . - pubmed
We present a case of an isolated acute dorsal dislocation of the distal radioulnar joint in a 25 - year - old man . - pubmed
However , the loop metavaccine with Freund 's complete adjuvant ( CFA ) reduced cancer progression and metastasis while that with alum , to our surprise , were adversely affected in 3 tumor bearing mouse models . - pubmed
Based on these observations , we concluded that multiple immune parameters are to be considered when applying a vaccine strategy to cancer patients . - pubmed
OBJECTIVES : To evaluate and compare the efficacy of National Early Warning Score , National Early Warning Score 2 , Rapid Emergency Medicine Score , Confusion , Respiratory rate , Blood pressure , Age 65 score , and quick Sepsis - related Organ Failure Assessment on predicting in - hospital death in patients with coronavirus disease 2019 . - pubmed
SETTING : Single center , West Campus of Wuhan Union hospital - a temporary center to manage critically ill patients with coronavirus disease 2019 . - pubmed
Disrupted Regional Homogeneity in Drug - Naive Patients With Bipolar Disorder . - pubmed
Objective : Studies on alterations in the regional neural activity in the brain of patients with bipolar disorder ( BD ) have provided conflicting results because of different medications used and study designs . - pubmed
This study aimed to further explore regional neural activities in unmedicated patients with BD and their association with BMD . - pubmed
Methods : In this study , 40 patients with BD and 42 healthy controls were scanned through resting - state functional magnetic resonance imaging ( fMRI ) . - pubmed
Conclusion : This study further confirms the abnormal brain activities in extensive regions , and these brain regions are primarily located in the fronto - temporal - occipital circuit and the cerebellum vermis of patients with BD . - pubmed
Effect of androgen deprivation therapy on cardiovascular function in Chinese patients with advanced prostate cancer : a prospective cohort study . - pubmed
Androgen deprivation therapy ( ADT ) is the standard treatment for advanced prostate cancer , but its effect on cardiovascular and metabolic function in Asian patients is still inconclusive . - pubmed
We prospectively assess the effects of ADT on 36 patients with advanced prostate cancer , with reference to another 24 prostate cancer patients not requiring ADT , for 2 years . - pubmed
ADT - patients were 4.9 times more likely to have metabolic syndrome at 24 months . - pubmed
Commentary on " Urtica dioica in comparison with placebo and acupuncture : A new possibility for menopausal hot flashes : A randomized clinical trial " by Rahele Kargozar et al . - pubmed
Adult patients ( at least 18 years of age ) undergoing open , elective , ventral hernia repairs with mesh placed in the retromuscular position were enrolled . - pubmed
Secondary outcomes included total inpatient opioid use , pain scores determined using a 100 mm visual analog scale , length of hospital stay , and patient - reported quality of life . - pubmed
Similarly , there were no differences in total inpatient opioid use , pain scores , length of stay , and patient - reported quality of life . - pubmed
RESULTS : We experienced differences in the usability of piggyBac - based germline transformation in different strains of D. - pubmed
RESULTS : We assessed 156 patients with nonsyndromic lower extremity VM ; 71 ( 46 % ) were focal , and 85 ( 54 % ) were diffuse type VM , and 97 ( 62 % ) were IA - VM . - pubmed
The YM / PU column implanted in the back subcutis or vagina of the mouse rapidly recovered to its original state within 60 s under a very low NIR laser ( 808 nm , 0.5 W / cm2 ) intensity , which is much lower than the general laser intensity for photothermal cancer therapy ( 1 - 2 W / cm2 ) . - pubmed
METHODS : Data regarding professions , wet work exposure , activities performed during working hours , self - reported eczema were collected from 230 nurse students , divided in two study groups : the intervention and the control group ( CG ) . - pubmed
The histology of the gastric mucosa of two subjects with severe lesions showed spotty to moderate chronic superficial gastritis , whereas the overall histological appearance of the mucosa was normal in subjects with slight or moderate lesions after drug administration . - pubmed
Sudden sensorineural hearing loss : electrocochleographic findings in 70 patients . - pubmed
The results of transtympanic ECochG in 70 patients with sudden sensorineural deafness are presented . - pubmed
ECochG gave a definite localization of the deafness in 22 out of 23 patients in whom conventional methods of audiometry had produced equivocal results and was also found to be extremely valuable in 17 patients with " dead " ears . - pubmed
[ Endoscopic control of patients subjected to vagotomy and drainage for duodenal ulcer . - pubmed
The usefulness of endoscopic examination of patients subjected to vagotomy and drainage for duodenal ulcer is stressed , since it permits recurrences and ineffective treatment to be detected , along with the control of other parameters , such as the appearance of the mucosa , the performance of gastric drainage , the features of peristalsis and gastric tone , and the performance of the cardial sphincter . - pubmed
Acoustic neurinoma in a child : a case study . - pubmed
This case study reports the audiological and surgical findings for a nine - year - old boy with an acoustic neurinoma . - pubmed
The patient had a 5 cm acoustic neurinoma compressing and adherent to the brain stem . - pubmed
[ Pathomorphology of human hepatic echinococcosis and alveococcosis ] . - pubmed
This apparent morphine - induced atrophy of these important accessory sex organs was not due to a change in the nutritional status of the animals but rather appeared to be associated with a pronounced ( 87 percent ) reduction in the serum testosterone levels of morphine - treated rats when compared to control levels . - pubmed
Sera from patients with tuberculoid leprosy and control sera gave very weak binding . - pubmed
leprae was obtained by immunochemistry of lepromatous leprosy lesions with a monospecific antibody raised against M. - pubmed
This probe does not hybridize to the DNA of non - toxigenic strains of C. - pubmed
A preliminary study of direct probing of faecal specimens indicates a potential for the use of this DNA probe in the clinical laboratory for the rapid identification of toxigenic strains of C. - pubmed
Fourteen adult patients undergoing open heart surgery under induced hypothermia had median nerve , short - latency somatosensory evoked potentials ( SSEPs ) recorded during cooling ( from 36 degrees C to 19 degrees C ) and subsequent rewarming . - pubmed
Between 1983 and 1990 , 59 patients with malignant melanoma were retrospectively reviewed to assess the safety , efficacy and the maximal tolerated dose of cisplatin used in hyperthermic isolated limb perfusion . - pubmed
In 75 % of patients in group 3 a traffic accident was the lesion mechanism . - pubmed
Selective cytotoxicity against human tumor cells by an anti - gastric cancer monoclonal antibody - mitomycin C conjugate . - pubmed
The conjugate showed a highly selective cytotoxicity upon human gastric cancer cells KATO - III . - pubmed
Supersensitivity of isolated coronary artery to ergonovine in a patient with variant angina . - pubmed
Na(+)-dependent , active nucleoside transport in mouse spleen lymphocytes , leukemia cells , fibroblasts and macrophages , but not in equivalent human or pig cells ; dipyridamole enhances nucleoside salvage by cells with both active and facilitated transport . - pubmed
Formycin B influx studies have shown that P388 and L1210 mouse leukemia cells , mouse L929 cells , mouse RAW 309 Cr.1 cells , LK35.2 mouse B - cell hybridoma cells and cultured mouse peritoneal macrophages express both Na(+)-dependent , active and nonconcentrative , facilitated nucleoside transport systems . - pubmed
Finally , cyst or follicle - like structures lined by immunostained cells with basal processes could be observed in the anterior lobe of the rat , but not in that of the rabbit or the cat . - pubmed
In 37 test persons with healthy vessels and 103 patients with arterial obstructive disease the clinical findings of the pulse palpation were related to the results of the systolic Doppler pressure measurement in the region of the posterior tibial artery . - pubmed
Effect of nifedipine on left ventricular function during exercise in patients with stable effort angina . - pubmed
To evaluate whether the effect of nifedipine on left ventricular function relates to the severity of coronary artery disease ( CAD ) or not , supine graded ergometer exercise testing was performed before and after sublingual administration of 10 mg nifedipine in 24 patients with stable effort angina . - pubmed
After nifedipine , left ventricular function ( % EF ) was improved in all 6 patients with mild CAD , but was worsened in all 9 patients with severe CAD . - pubmed
Maximal ST segment depression during exercise was improved in 5 of 6 patients with mild CAD , while improvement was induced in 5 of 9 patients with moderate CAD and in 3 of 9 patients with severe CAD . - pubmed
At the Radiotherapeutic Department of the Faculty of Medicine in Istanbul , 35 masculine patients with microcellular bronchial carcinoma , limited disease , were treated for two years , i.e. - pubmed
Nine out of these patients are tumor - free after at least 46 months , i.e. - pubmed
Four patients with chlorpromazine - induced pigmentation showed resolution of the condition on replacing chlorpromazine with haloperidol . - pubmed
Risks to postoperative patients include an increase in metabolic rate of up to 400 % , hypoxemia , wound dehiscence , dental damage , and disruption of delicate surgical repairs . - pubmed
Signals from each muscle were compared to those of pathologic clonus induced by plantar flexion in unanesthetized patients with spinal cord transections and to those of cold - induced shivering in normal , unanesthetized subjects . - pubmed
Two distinct EMG patterns were identified : 1 ) regular , bursting signals of 5 - 7 Hz similar to those produced by pathologic clonus in patients with spinal cord transections ; and 2 ) tonic , irregular signals of 5 - 15 Hz which had poorly defined bursts that did not demonstrate the synchronous 4 - 8 - cycle / min waxing and waning pattern typical of normal shivering . - pubmed
During the later part of recovery when isoflurane concentrations were less than or equal to 0.1 % , hypothermic patients frequently demonstrated no clinical or EMG evidence of muscular activity. - pubmed
One hundred and sixty - five patients with localized cancer of the lower lip were excised and reconstructed over a 25 - year period using Bengt Johanson 's step technique . - pubmed
Nine local recurrences appeared in 5 patients , none of whom died of lip cancer . - pubmed
Eight patients later developed regional metastases and 3 of these patients died of lip cancer . - pubmed
The I score was used to divide patients into groups at different risk of recurrence : low , moderate and high ( 97.5 % , 45 % and 22.5 % of recurrence - free patients at 3 years respectively ) . - pubmed
Rapid fluid replacement for severe hypovolemia -- human subject trials . - pubmed
Successful resuscitation of a hypovolemic patient often requires rapid intravenous administration of massive amounts of fluid . - pubmed
We report the system 's use in five patients with severe hypovolemia following trauma . - pubmed
The investigations have been made in children aged 1.5 - 4 years , immunized with live measles vaccine prepared from strain l-16 . - pubmed
Effect of functional rehabilitation on blood lipid values in a group of patients with neuromotor lesions ] . - pubmed
[ Etiology of intestinal disorders in young children with acute respiratory diseases ] . - pubmed
Immunoelectrophoretic characteristics of plasma from rats with adjuvant arthritis . - pubmed
Binding to R 1881 ( methyltrienolone ) of proteins from human benign prostatic hypertrophy . - pubmed
Cytosol of human benign prostatic hypertrophy bound to R 1881 in a high affinity manner . - pubmed
Four patients developed abnormal involuntary movements of a limb after injury . - pubmed
Sympathetic block in three patients did not relieve the abnormal movements . - pubmed
[ Nomenclature for strains of poliovirus ] . - pubmed
Staphylocidal defect of polymorphonuclear leukocytes in a patient with leprechaunism . - pubmed
Cerebrospinal fluid flow abnormalities in patients with neoplastic meningitis . - pubmed
Cerebrospinal fluid flow dynamics were evaluated by 111Indium - diethylenetriamine pentaacetic acid ( 111In - DTPA ) ventriculography in 27 patients with neoplastic meningitis . - pubmed
These data indicate that cerebrospinal fluid flow abnormalities are common in patients with neoplastic meningitis and that 111In - DTPA cerebrospinal fluid flow imaging is useful in characterizing these abnormalities . - pubmed
This technique provides insight into the distribution of intraventricularly administered chemotherapy and may provide explanations for treatment failure and drug - induced neurotoxicity in patients with neoplastic meningitis . - pubmed
160 mice of the BALB / C strain of both sexes , aged 3 months , were divided into four equal groups out of which two were regularly irritated by a combination of an optical signal and electrical stroke . - pubmed
Thus , the method is considered to be quite beneficial in taking care of advanced cancer patients . - pubmed
Idiopathic osteonecrosis of the femoral capital epiphysis in children . - pubmed
Two patients with minimal amyloid deposition in association with nephrotic syndrome are reported . - pubmed
In this study , we used a rat model of middle cerebral artery occlusion ( MCAO ) of permanent focal ischemia . - pubmed
Normothermic animals ( n = 13 ) had a baseline glutamate concentration of 9.23 + /- 2.5 mumol / ml ( mean + /- standard error of the mean ) before MCAO . - pubmed
Clinical studies in Alzheimer patients with positron emission tomography . - pubmed
Brain imaging techniques will in the future play an important role in the assessment of patients with neurogenerative disorders such as Alzheimer ' s disease ( AD ) . - pubmed
Longitudinal studies will here be important and especially in individuals with a family history of AD . - pubmed
A reduced uptake and binding of [ 11C ] nicotine in the temporal and frontal cortices have been measured in AD patients by PET . - pubmed
PET studies indicate that long - term tacrine treatment in AD patients with mild dementia improves functional activities in brain . - pubmed
COM stones were found in older patients than COD stones ( p & lt ; 0.05 ) ; 45.2 + /- 12.8 and 39.9 + /- 11.2 years old for 51 COM stone patients and 54 COD stone patients . - pubmed
Fifty - three patients were followed at yearly intervals without any prophylactic treatment for stone recurrence . - pubmed
Identification in the sera from patients with advanced cancer of a factor which stimulates gene expression from human immunodeficiency virus type 1 . - pubmed
These results suggest that the onset of cellular and humoral immune responses after immunization may be important as a biological control of myiasis and contribute to better understanding of the immune defense mechanism of the host against D. - pubmed
Exhaled nitric oxide may be a useful marker of inflammation and has recently been shown to be increased in patients with asthma . - pubmed
OBJECTIVE : The purpose of this study was to determine whether exhaled levels of nitric oxide are increased with nasal breathing in patients with seasonal allergic rhinitis compared with nonatopic individuals and whether there is an increase with oral breathing consistent with lower respiratory inflammation in the absence of clinical asthma . - pubmed
METHODS : Nitric oxide levels in exhaled air were measured by chemiluminescence in 18 nonatopic volunteers and 32 patients with seasonal rhinitis . - pubmed
Levels of exhaled nitric oxide were significantly higher for all measurements in patients with seasonal rhinitis , with levels without breath - holding of 35.4 + /- 11.3 ppb ( p less than 0.001 ) in nasally exhaled air and 16.3 + /- 5.9 ppb ( p less than 0.001 ) in orally exhaled air . - pubmed
CONCLUSIONS : The results indicate that exhaled nitric oxide may be a useful marker for nasal inflammation in patients with seasonal rhinitis and suggest that generalized airway inflammation may be present , even without clinical asthma , in such patients . - pubmed
Thirty parturients undergoing elective cesarean section under spinal anesthesia were randomly allocated to receive postoperative pain management with ( S - E group , n = 15 ) or without epidural bupivacaine ( S group , n = 15 ) . - pubmed
Our sample included an initial group of 40 patients who had growth delay / constitutional delay of growth and puberty ( n = 10 ) , growth hormone insufficiency / deficiency ( n = 15 ) , low birth weight / Silver - Russell syndrome ( n = 9 ) , precocious puberty ( n = 6 ) , as well as 20 patients with various skeletal dysplasias ( multiple epiphyseal dysplasia n = 7 , pseudoachondroplasia n = 7 , acrodysostosis n = 5 , achondroplasia n = 1 ) , 7 girls with Turner syndrome , and 10 boys with nephrotic syndrome on chronic corticosteroid treatment . - pubmed
Depression of A and C fibre - evoked segmental reflexes by morphine and clonidine in the in vitro spinal cord of the neonatal rat . - pubmed
Under exercise conditions where untrained animals demonstrate substantial reductions in blood glucose , training enhanced hypoglycemic resistance has been shown to result entirely from enhanced glucose production via gluconeogenesis . - pubmed
It is concluded that the improved hepatic gluconeogenic capacity of endurance trained individuals , at least in rats , is critical to their demonstrated resistance to exercise - induced hypoglycemia . - pubmed
The effects of sevoflurane on recovery of brain energy metabolism after cerebral ischemia in the rat : a comparison with isoflurane and halothane . - pubmed
Conversely , topical corticosteroids may suppress the development of local cutaneous irritation that occurs in patients treated with calcipotriene ointment . - pubmed
OBJECTIVES : We report the occurrence of cardiac events during long - term follow - up in patients with hypertrophic cardiomyopathy ( HCM ) after cardioverter - defibrillator implantation . - pubmed
BACKGROUND : The identification of patients at high risk for sudden death and the prevention of recurrence of sudden death in HCM represents a difficult problem . - pubmed
METHODS : We retrospectively analyzed the occurrence of cardiac events during follow - up of 13 patients with HCM who received an implantable cardioverter - defibrillator ( ICD ) because of aborted sudden death ( n = 10 ) or sustained ventricular tachycardia ( n = 3 ) ( group I ) . - pubmed
RESULTS : After a mean ( + /-SD ) follow - up period of 26+/-18 months , 2 of 13 patients in group I received appropriate shocks . - pubmed
We observed a low incidence of recurrence of ventricular tachycardia / fibrillation during follow - up in patients with HCM . - pubmed
CONCLUSIONS : Our data suggest that ventricular tachyarrhythmias may not always be the primary mechanism of syncope and sudden death in patients with HCM . - pubmed
The ICD seems to have a less important impact on prognosis in patients with HCM than in patients with other etiologies of aborted sudden death . - pubmed
The overall prevalence of mixed infections , assessed by PCR , was 37.1 % ; the majority ( 72.7 % ) involved T. - pubmed
Prediction of axillary lymph node involvement of women with invasive breast carcinoma : a multivariate analysis . - pubmed
METHODS : We examined 308 patients presenting with suspected but not previously known CAD who underwent selective coronary angiography . - pubmed
CONCLUSIONS : Coronary calcium predicts the angiographic extent of CAD in symptomatic patients and provides independent and incremental information to the more conventional clinical parameters derived from SPECT or risk assessment . - pubmed
Because cytomegalovirus ( CMV ) is an important opportunistic infection after liver transplant , we conducted a prospective study to see if the same applied to human herpesviruses ( HHV)-6 and -7 . - pubmed
Active infection with CMV was detected in 28/60 ( 47 % ) , HHV-6 in 19/60 ( 32 % ) , and HHV-7 in 29/60 ( 48 % ) of patients . - pubmed
The median peak virus load for CMV was significantly greater than that for HHV-6 or HHV-7 . - pubmed
Detailed clinicopathological analyses for the whole population showed that CMV and HHV-6 were each significantly associated with biopsy - proven graft rejection . - pubmed
Individual case histories suggested that HHV-6 and HHV-7 may be the cause of some episodes of hepatitis and pyrexia . - pubmed
It is concluded that HHV-6 is a previously unrecognized contributor to the morbidity of liver transplantation , that HHV-7 may also be important and that both viruses should be included in the differential diagnosis of graft dysfunction . - pubmed
Following comprehensive literature search and communication with other researchers , 34 items about viral load testing , HIV therapies and concern about HIV infection were generated . - pubmed
The knockout study also suggested that the brain of PIMT - deficient mice manifested neurodegenerative changes concomitant with accumulation of L - isoaspartate . - pubmed
We discuss the pathological implications of protein isomerization in the neurodegeneration found in model mice and AD . - pubmed
First case was a 27 - year - old man with cerebral palsy . - pubmed
Second case was a 55 - year - old man with lung cancer , terminal stage . - pubmed
Third case was a 60 - year - old man with amyotrophic lateral sclepsis . - pubmed
The aim of this investigation was to study retinol , which is known to decrease in hepatic stellate cells during fibrogenesis , and dolichol , which influences membrane fluidity and decreases in liver injury , in freshly isolated liver parenchymal and nonparenchymal cells after intoxication of rats with CCl4 combined with the ionophore monensin for 3 , 5 and 7 weeks . - pubmed
PURPOSE : To determine whether the blastocyst zona shedding process within the murine uterine cornus in vivo is due to a global lytic process caused by uterine proteolytic enzyme , or is triggered by the blastocyst hatching process as observed in vitro . - pubmed
Dynamics of porcine circovirus type 2 infection in a herd of pigs with postweaning multisystemic wasting syndrome . - pubmed
OBJECTIVE : To determine the pattern of infection for porcine circovirus type 2 ( PCV2 ) in a herd of pigs with postweaning multisystemic wasting syndrome ( PMWS ) . - pubmed
RESULTS : The PMWS started when pigs were 8 weeks old , with a prevalence of 30 % in 8- to 10 - week - old pigs . - pubmed
Microscopic lesions consistent with PMWS were observed , and PCV2 nucleic acid was detected ( 50 of 68 pigs ) . - pubmed
CONCLUSIONS AND CLINICAL RELEVANCE : Infection with PCV2 coincided with severe clinical signs ; however , infected 28 - week - old pigs did not have evidence of disease . - pubmed
A long duration of PCV2 viremia was apparent in a high percentage of infected pigs , which may affect transmission and persistence of the virus in a herd . - pubmed
BACKGROUND : The objective of this study was to comprehensively characterize the clinical and biologic features of adenoid cystic carcinoma ( ACC ) and to assess the implications for management in a large cohort of patients . - pubmed
METHODS : From a database of 50,000 patients , 28 were identified with ACC for which clinical follow - up and biologic information was available . - pubmed
One patient had macroscopic metastatic disease at diagnosis . - pubmed
METHODS : A 53 - year - old male with chronic myeloid leukemia presented with prolonged involuntary painful erection of 12 hours ' duration . - pubmed
BK polyomavirus interstitial nephritis in a renal transplant patient with no previous acute rejection episodes . - pubmed
This case shows that even in the absence of vigorous anti - rejection therapy an immunosuppressive regimen based on tacrolimus and MMF may involve the risk of BK polyoma virus- associated interstitial nephritis . - pubmed
A total of 332 patients treated for chronic HCV infection were evaluated . - pubmed
Using multivariate logistic regression analysis , the impact of the rate of fibrosis progression ( defined as the stage of liver fibrosis according to the Metavir system / duration of infection ) on the rate of SVR ( negative HCV RNA at least 6 months following the end of treatment ) , was determined . - pubmed
The median rate of fibrosis progression was 0.083 ( range 0 - 2 ) Metavir units / year ; 158 patients ( 48 % ) had F2 - F4 fibrosis . - pubmed
In this study , a total of 225 methicillin resistant Staphylococcus aureus strains isolated from various clinical specimens ( 114 wounds , 27 blood , 16 of each catheter and sputum , 14 throat swabs , 10 tracheal aspirates , 7 of each urine and drain materials , 6 pleural fluids , 5 graft materials , 2 cerebrospinal fluids , 1 ascitis fluid ) of hospitalized patients , were tested in - vitro for their susceptibilities to fusidic acid and trimethoprim - sulfamethoxazole ( TMP - SMX ) by disk diffusion method . - pubmed
Molecular analysis of Staphylococcus aureus blood isolates shows lack of polyclonal bacteremia . - pubmed
Molecular analysis of the first blood culture from 41 patients with Staphylococcus aureus bacteremia and 20 bacteremia - associated catheter tip isolates revealed indistinguishable blood colonies in 39 patients ( 95.1 % ) and two related variants in two patients ( 4.9 % ) . - pubmed
Good surgical technique and local anti - hemorrhagic treatment are essential in oral surgery , particularly in patients taking anti - platelets or oral anticoagulants . - pubmed
Adrenal cortical insufficiency in the rhesus monkey . - pubmed
REPORT ON FERTILITY AFTER VIRILIZATION WITH ANDROGENS IN A MAN WITH MINUTE TESTICLES AND EUNUCHOIDISM . - pubmed
All rabbits were bled for evaluation of hematologic parameters for the stress triad ( neutrophilia , lymphopenia , and eosinopenia ) and weighed weekly . - pubmed
No significant differences were found between study and control rabbits when body weights , food consumption , and hematologic parameters were analyzed . - pubmed
Some hypotensive preterm infants have low cortisol levels , and corticosteroids are being used increasingly to prevent or treat hypotension in these babies . - pubmed
HORTON ' S SYNDROME , A VASCULAR DISEASE : The destruction of the arterial wall at the acute stage of the disease appears responsible , sometimes later on , for aneurismal dilatations observed on the aorta of certain patients . - pubmed
A viral role in the development of lymphomas and of Kaposi sarcoma in HIV - infected individuals would account for neoplastic aggressiveness and for a particular predilection for primary CNS lymphoma . - pubmed
Such a role perhaps implicates viral integration within the genome of host cells that are actively proliferating or else infected by multiple viral pathogens such as EBV , HIV-1 , CMV , and Herpes virus . - pubmed
UNLABELLED : Hepatocellular carcinoma ( HCC ) is an important type of cancer etiologically related to some viruses , chemical carcinogens and other host or environmental factors associated to chronic liver injury in humans . - pubmed
Women in group 1 had nine urinary tract injuries ( 3.28 % ) , including eight cases of intraoperative bladder injury ( 2.91 % ) and one vesicovaginal fistula ( 0.36 % ) , but no ureteral injury . - pubmed
METHODS : We observed the survival time to hypoxia and heat survival rate of the mice treated with different doses of PHAS and vitamin E. - pubmed
Whereas first - episode patients showed significantly diminished flush response as compared to controls , comparable differences were not found between multi - episode patients and controls . - pubmed
METHODS : Both studies were 8 - week , double - blind , comparison studies of men and women with DSM III - R major depression . - pubmed
This study aimed to : classify a cohort of children and adolescents with myotonic dystrophy ( dystrophia myotonica : DM ) into congenital and childhood onset forms ; estimate CTG expansion size ; and quantify muscle strength , contractures , and motor function in children with DM and compare results with those of controls . - pubmed
Participants were : 42 children with DM ( 18 females , 24 males ; mean age 8y 9mo [ SD 4y 7mo ] , range 10mo to 17y ) and 42 age- and sex - matched , healthy controls . - pubmed
Children with DM were divided into three groups : severe congenital ( n=13 ) , mild congenital ( n=15 ) , and childhood ( n=14 ) . - pubmed
Children with childhood DM were significantly weaker than controls ( wrist and ankle dorsiflexors [ p=0.0044 , p=0.0044 respectively ] ; hip abductors and flexors [ p=0.0464 , p=0.0217 ] ; and knee flexors and extensors : [ p=0.0382 , p=0.0033 ] ) . - pubmed
Children with mild congenital DM were significantly weaker than controls in all assessed muscle groups . - pubmed
Children with severe congenital DM had the lowest motor function , with correlation between motor function and size of CTG repeat ( p=-0.743 ) . - pubmed
Prevalence of atherosclerosis of the coronary and extracranial cerebral arteries in patients undergoing aortic valve replacement for calcified stenosis . - pubmed
METHODS : In 282 consecutive patients with severe calcific stenosis of a tricuspid aortic valve scheduled for aortic valve replacement , the prevalence of atherosclerotic changes of the coronary and extracranial cerebral arteries were assessed using coronary angiography and Doppler sonography , respectively . - pubmed
Coronary or extracranial cerebral artery stenosis was present in 59 % and 16 % of patients , respectively , while 91 % of the study population and all patients aged & gt ; 80 years showed atherosclerosis of the coronary and/or extracranial cerebral arteries . - pubmed
CONCLUSION : The data obtained indicated a very high prevalence of atherosclerotic changes in patients with calcific AS , suggesting pathogenetic similarities of both disorders . - pubmed
Routine screening of the extracranial cerebral arteries is warranted in all patients with calcific AS and scheduled for valve replacement . - pubmed
The potential for enhancement of mouse melanoma metastasis by diagnostic and high - amplitude ultrasound . - pubmed
The melanoma cell line B16 - D5 , which is metastatic specifically to lung , was cultured and implanted on a hind leg of female C57 / bl6 mice . - pubmed
We analyzed event - related potentials ( ERPs ) and behavioral measurements during a recognition memory task in 15 normal elderly subjects and 15 patients with Parkinson ' s disease ( PD ) . - pubmed
Long - term low - molecular - weight heparin versus usual care in proximal - vein thrombosis patients with cancer . - pubmed
PURPOSE : A substantial clinical need exists for an alternative to vitamin K antagonists for treating deep - vein thrombosis in cancer patients who are at high risk of both recurrent venous thromboembolism and bleeding . - pubmed
SUBJECTS AND METHODS : Subjects were patients with cancer and acute symptomatic proximal - vein thrombosis . - pubmed
Bleeding , largely minor , occurred in 27 patients ( 27 % ) receiving tinzaparin and 24 patients ( 24 % ) receiving usual care ( absolute difference -3.0 ; 95 % CI , -9.1 to 15.1 ) . - pubmed
In patients without additional risk factors for bleeding at the time of randomization , major bleeding occurred in 0 of 51 patients ( 0 % ) receiving tinzaparin and 1 of 48 patients ( 2.1 % ) receiving usual care . - pubmed
CONCLUSION : Our findings confirm the limited but benchmark data in the literature that long - term low - molecular - weight heparin is more effective than vitamin - K - antagonist therapy for preventing recurrent venous thromboembolism in patients with cancer and proximal venous thrombosis . - pubmed
These results indicate that ischaemia activates caspases shortly after reperfusion and that the sex of the animal may strongly influences apoptotic pathways in the pathogenesis of neonatal brain injury . - pubmed
METHODS : This retrospective review examined 207 normal eyes of patients undergoing an initial consultation for primary refractive surgery and 42 eyes with clinical keratoconus ( KCN ) . - pubmed
METHODS : Two blinded trained observers scored 95 AS radiographs from a cohort of AS patients . - pubmed
SELECTION CRITERIA : Randomized trials comparing antibiotic treatment with placebo or no treatment in pregnant women with asymptomatic bacteriuria found on antenatal screening . - pubmed
RESULTS : Desaturation developed during 1 procedure , and there was hypotension in 5 patients . - pubmed
In addition , cardiac arrest occurred intraoperatively in 1 patient , which was the only fatality . - pubmed
Five months after presentation , decreased vision and epiretinal membrane formation associated with development of a full - thickness macular hole were observed in the first patient . - pubmed
In the second patient , a full - thickness macular hole was demonstrated by optical coherence tomography 6 weeks after presentation . - pubmed
Validation of the BrockTB stat - pak assay for detection of tuberculosis in Eurasian badgers ( Meles meles ) and influence of disease severity on diagnostic accuracy . - pubmed
A lateral - flow immunoassay ( BrockTB Stat - Pak ) for detecting tuberculosis in Eurasian badgers was 49 % sensitive and 93 % specific against culture for M. - pubmed
METHODS : Nine patients with acute hyperlipidemic pancreatitis were treated with DFPP in addition to the conventional therapeutic measures . - pubmed
CONCLUSION : DFPP can be effectively and safely applied in patients with acute hyperlipidemic pancreatitis . - pubmed
METHODS : Thirty - nine patients with HCM underwent cine steady - state , free - precession and delayed contrast - enhanced , inversion - recovery , gradient - echo MRI . - pubmed
RESULTS : Among the 39 patients , 2 showed apical aneurysm and 17 showed apical thinning . - pubmed
A few patients with apical thinning had some common features to apical aneurysm such as myocardial apical myocardial hyperenhancement . - pubmed
Early childhood infection by human herpesvirus 8 in Zambia and the role of human immunodeficiency virus type 1 coinfection in a highly endemic area . - pubmed
Kaposi ' s sarcoma occurs at high incidence among Zambian adults and children , but there is a paucity of data on human herpesvirus 8 ( HHV-8 ) incidence and routes of infection , especially in children . - pubmed
The incidence rate of HHV-8 seroconversion was 13.8 infections per 100 child - years by 48 months of age . - pubmed
Maternal HIV-1 and HHV-8 infection status were not independently associated with risk of HHV-8 seroconversion in the child . - pubmed
Despite a long history of widespread use , objective evidence that administration of sodium bicarbonate improves outcomes for patients in cardiopulmonary arrest or with metabolic acidosis is lacking . - pubmed
One patient with closed wounds had transient hypotony along with shallow peripheral choroidals noted on postoperative day 1 , which resolved on their own . - pubmed
MATERIALS AND METHODS : We present a case of a 55 - year - old man who was having ischemic symptoms related to severe middle cerebral artery stenosis . - pubmed
Current recommended dosing of vancomycin for children with invasive methicillin - resistant Staphylococcus aureus infections is inadequate . - pubmed
BACKGROUND : Vancomycin area - under - the - concentration - time - curve ( AUC ) for 24 hours divided by the minimum inhibitory concentration ( MIC ) ( AUC24 / MIC ) & gt;400 optimally treats invasive methicillin - resistant Staphylococcus aureus ( MRSA ) infections in adults . - pubmed
CONCLUSIONS : A vancomycin dose of 40 mg / kg / d in children is unlikely to achieve the recommended pharmacodynamic target of AUC24 / MIC & gt;400 for invasive MRSA infections even when MIC is 1.0 microg / mL. - pubmed
Sepsis affects 40 % of critically ill patients , with a reported mortality of approximately 30 % in severe sepsis , raising to 75 % when acute kidney injury ensues , which occurs in about 20 - 51 % of cases . - pubmed
The present study consists on a one - year prospective , observational , longitudinal trial undergone in 80 severe septic patients to determine the risk of development of acute kidney injury and its relationship with mortality ; the association of the clinical course and blood parameter variations with mortality ; the severe sepsis mortality rate ; an eventual correlation between death and septic focus , and to assess mortality predictibility based on initial creatinine levels and final variations . - pubmed
OBJECTIVE : To establish differential protein expression profile specific for serum proteome of cervical carcinoma in Uighur women by protein 2 - dimensional liquid phase chromatography . - pubmed
CONCLUSION : Two - dimensional liquid phase chromatography is an effective and feasible method to establish differential expression profile of serum proteome and to offer a new way for the screening of serum protein markers of Uighur women with cervical carcinoma . - pubmed
PURPOSE : To describe retrospectively the overall survival , the cancer specific survival and the tumor control in an homogeneous series of patients with epidermoid carcinoma of the anal canal treated with definitive radiotherapy ; to assess the impact of brachytherapy , chemotherapy and pre - radiotherapy resection on the risk of recurrence . - pubmed
Five patients recurred ( 5 - year rate : 12 % : four had local relapse ( 5 - year rate : 8 % ) , four had groin recurrence , and distant metastases were seen in two . - pubmed
In univariate analysis , the risk of relapse was higher in patients who had undergone a pre - radiation excision ( p=0.018 ) , in those who did not receive chemotherapy ( p=0.076 ) and in those who were irradiated on a belly board ( p=0.049 ) . - pubmed
CONCLUSION : Radiotherapy and chemoradiation with cisplatine - based chemotherapy cure a vast majority of patients with epidermoid carcinoma of the anal canal . - pubmed
Patients with perivenous demyelination ( n = 13 ; median age 43 years , range 5 - 67 ) on brain biopsy and/or autopsy , ascertained retrospectively , were compared with a cohort with confluent demyelination only ( n = 91 ; 84 % multiple sclerosis , 16 % isolated syndrome at follow - up ; median age 39 years , range 10 - 69 ) . - pubmed
Among the perivenous demyelination cohort , 10 patients had only perivenous demyelination and three also had confluent demyelination . - pubmed
All but one patient with perivenous demyelination only had a monophasic course , whereas two of three with both types had a relapsing course . - pubmed
A distinct pattern of cortical microglial activation and aggregation without associated cortical demyelination was found among six perivenous demyelination patients , all of whom had encephalopathy and four of whom had depressed level of consciousness . - pubmed
This pattern of cortical pathology was not observed in the confluent demyelination cohort , even in one patient with depressed level of consciousness . - pubmed
Clinical criteria were 80 % sensitive and 91 % specific for pathologically defined acute disseminated encephalomyelitis ( perivenous demyelination ) , but misdiagnosed acute disseminated encephalomyelitis among 9 % of patients with confluent demyelination and multiple sclerosis diagnosis at last follow - up . - pubmed
Depressed level of consciousness is a more specific clinical criterion for pathologically confirmed acute disseminated encephalomyelitis than encephalopathy , which over - diagnosed acute disseminated encephalomyelitis among multiple sclerosis patients . - pubmed
Although pathological evidence of perivenous demyelination may be superior to clinical criteria for diagnosing acute disseminated encephalomyelitis , the co - occurrence of perivenous and confluent demyelination in some individuals suggests pathogenic overlap between acute disseminated encephalomyelitis and multiple sclerosis and misclassification even with biopsy . - pubmed
In 1990 - 2006 Tashkent Medical Academy Clinic admitted 71 patients ( 63 boys and 8 girls ) with subtotal and total forms of epispadia which in some cases combined with extrophy of the bladder . - pubmed
The aim of the study was to evaluate the role dynamic magnetic resonance imaging defecography , and to elucidate the underlying anatomic and pathophysiologic background of pelvic floor disorders in these patients in order to minimize failures . - pubmed
RESULTS : The dynamic MRI of the pelvic floor showed 23 patients with descending perineum , 32 rectoceles ( 28 females ) , 12 cystoceles ( 10 females ) , 6 enteroceles ( 4 females ) , 18 intussusceptions ( 14 females ) , and 7 dyskinetic puborectalis muscle ( 3 females ) . - pubmed
The diagnosis of combined pelvic floor disorders with dynamic MRI defecography was consistent with clinical results in 70 % and there were additional diagnostic parameters in 30 % of patients . - pubmed
METHODS : The antitumour activities and related mechanisms of WP1066 were investigated in vitro on renal cancer cell lines and in vivo on murine xenografts . - pubmed
Pilot study of a combination of S-1 and paclitaxel for patients with peritoneal metastasis from gastric cancer . - pubmed
BACKGROUND : This pilot study was carried out to evaluate the efficacy of chemotherapy for patients with peritoneal dissemination from gastric cancer or positive lavage cytology diagnosed by staging laparoscopy . - pubmed
After five courses of this therapy , the primary gastric tumors were evaluated and second - look laparoscopy was performed for patients showing partial response or stable disease with clinical benefit . - pubmed
No viable cancer cells were detected on cytopathological investigation during second - look laparoscopy in 9 patients who underwent surgical treatment . - pubmed
Leucopenia of grade 3 and neutropenia of grade 3 were recognized in two and three patients , respectively . - pubmed
We plan to study this regimen further in gastric cancer patients with peritoneal dissemination . - pubmed
Bilirubin and its oxidative metabolite biopyrrins in patients with acute myocardial infarction . - pubmed
This study aimed to assess the involvement of bilirubin and its oxidative metabolite biopyrrin in patients with acute myocardial infarction ( AMI ) and to determine the responsible organs that overproduce these molecules . - pubmed
One hundred thirteen consecutive patients hospitalized for AMI were analyzed . - pubmed
Serum bilirubin and its metabolite biopyrrins were elevated in patients with AMI . - pubmed
Polarization - based linear birefringence is measured on the myocardium of adult rat hearts after myocardial infarction and compared with hearts that had received mesenchymal stem cell treatment . - pubmed
Based on the pharmacokinetics of nitroxides in mice , half - life mapping was demonstrated in an ischemia - reperfusion model mouse brain . - pubmed
BACKGROUND : Dysregulated expression of microRNAs ( miRNAs ) has been previously observed in human cancer tissues and shown promise in defining tumor status . - pubmed
Clinical isolates were collected from throughout the US from dogs ( n=157 ) or cats ( n=43 ) with naturally occurring infection between March 2008 and January 2010 . - pubmed
Advantages of radio frequency ( RF ) cone biopsy compared to large loop excision of the transformation zone ( LLETZ ) in patients with high - grade squamous intraepithelial lesions : a retrospective study . - pubmed
OBJECTIVE : The aim of this study was to compare radio wave cone biopsy to the LLETZ method in patients with high - grade squamous intraepithelial lesions . - pubmed
METHOD - RESULTS : This was a retrospective study of 186 patients diagnosed with HGSIL who underwent cone biopsy either with the LLETZ method ( 82/186 ) or with the radio wave method ( 104/186 ) in the 2nd Obstetrics and Gynecology Department , University of Athens , Aretaieion Hospital , Athens , Greece during the period January 1999 to December 2008 . - pubmed
Histopathological analysis revealed focal or extensive high - grade squamous intraepithelial neoplasia extending into the underlying endocervical glands in 128/186 patients . - pubmed
Concomittent low - grade squamous intraepithelial lesions were observed in 160/186 patients and coilocytic atypia was observed in 172/186 patients . - pubmed
Zebrafish as a genomics model for human neurological and polygenic disorders . - pubmed
While in model organisms such as the zebrafish , mutants are sought that disrupt the function of individual genes , human mutations that cause , or are associated with , the development of disease , are often not acting in a Mendelian fashion , are frequently of small effect size , are late onset , and may reside in noncoding parts of the genome . - pubmed
A critical advantage is the ease of zebrafish transgenesis , both for the testing of human regulatory DNA driving expression of fluorescent reporter proteins , and the expression of mutated disease - associated human proteins in specific neurons to rapidly model aspects of neurological disorders . - pubmed
Potential drug development candidates for human soil - transmitted helminthiases . - pubmed
While generally safe and effective in reducing intensity of infection , they are contra - indicated in first - trimester pregnancy and have suboptimal efficacy against Trichuris trichiura . - pubmed
Neoadjuvant therapy was used in 57.1 % of patients with carcinoma . - pubmed
METHODS : Twenty - three adolescent girls with epilepsy aged from 8 to 14 years were treated with VPA for 1 year . - pubmed
CONCLUSIONS : VPA treatment for 1 year does not increase serum levels of androgen in adolescent girls with epilepsy , suggesting that VPA is an ideal choice of treatment for the girls . - pubmed
Among groups of herring injected with VHSV , the prevalence of infection was dose - dependent , ranging from 100 % , 75 % and 38 % after exposure to 19 , 0.7 and 0.07 plaque - forming units ( PFU)/fish , respectively . - pubmed
Among Pacific herring exposed to waterborne VHSV ( 140 PFU mL(-1 ) ) , the prevalence of infection , geometric mean viral tissue titre and cumulative mortality were greater among cohabitated herring than among cohorts that were held in individual aquaria , where fish - to - fish transmission was prevented . - pubmed
INTRODUCTION : Up to one in five people may have generalised anxiety disorder ( GAD ) at some point , and most have other health problems . - pubmed
Cortical blindness in a child with acute glomerulonephritis . - pubmed
The association between hypertensive encephalopathy and cortical blindness in children with acute glomerulonephritis is extremely rare . - pubmed
We analyzed the electrophysiological features in four patients from Brazil who fulfilled the clinical criteria for SPS . - pubmed
The clinicoradiologic findings and histological analysis of mandibular lesions in two patients who reported at the Dental Centre of the University College Hospital , Ibadan , Nigeria , are presented . - pubmed
The two patients were diagnosed of mandible osteosarcoma occurring concurrently with bilateral mandibular focal cemento - osseous dysplasia . - pubmed
Facial and vocal affect perception in people at ultra - high risk of psychosis , first - episode schizophrenia and healthy controls . - pubmed
METHODS : Seventy - nine ultra - high risk patients , 30 first - episode schizophrenia patients and 30 healthy control subjects completed a facial affect labelling test and an affective prosody recognition test . - pubmed
Establishing a brain - death donor model in pigs . - pubmed
INTRODUCTION : An animal model that imitates human conditions might be useful not only to monitor pathomechanisms of brain death and biochemical cascades but also to investigate novel strategies to ameliorate organ quality and functionality after multiorgan donation . - pubmed
METHODS : Brain death was induced in 15 pigs by inserting a catheter into the intracranial space after trephination of the skull and augmenting intracranial pressure until brain stem herniation . - pubmed
All 15 animals showed typical signs of brain death such as diabetes insipidus , hypertensive and hypotensive periods , as well as tachycardia . - pubmed
DISCUSSION : Brain death can be induced in a pig model by inserting a catheter after trephination of the skull . - pubmed
According to standard guidelines the brain - death diagnosis was established by a flat - line EEG , which occurred in all animals at 60 minutes after induction . - pubmed
Efficacy , pharmacokinetics , and safety of adalimumab in pediatric patients with juvenile idiopathic arthritis in Japan . - pubmed
The objective of this study was to evaluate the efficacy , pharmacokinetics , and safety of adalimumab in patients with polyarticular juvenile idiopathic arthritis ( JIA ) in Japan . - pubmed
Six patients ( all with MTX ) experienced nine serious AEs ( JIA , pyrexia , arthralgia , pneumonia , hepatitis B infection , pharyngitis , dehydration , pharyngeal pain , and pneumonia ) . - pubmed
In pediatric patients with polyarticular JIA in Japan , adalimumab was safe and effective for reducing disease activity for up to 60 weeks . - pubmed
Genes associated to antibiotic resistance and microbial virulence previously identified in organisms with human health significance were detected in these aeromonads , suggesting that these waters may act as a pivotal route for infections . - pubmed
Thirty children ( 60 ears ) , 2 - 16 years old ( mean age 7.06 + - 2.77 years ) who were planned to undergo surgical intervention for bilateral otitis media with effusion ( OME ) , were included in this study . - pubmed
Both ears were examined intraoperatively for bleeding , and patients were evaluated for myringosclerosis formation with otomicroscopy at the end of the ninth month . - pubmed
Salmonella typhi is a pathogen that causes the human disease of typhoid fever . - pubmed
We also highlight the importance of autonomic cardiac control in psychiatric disorders of social dysfunction and suggest that heart rate variability ( HRV)-an index of autonomic cardiac control - may play a key role in patient response in treatment trials of OT . - pubmed
The investigated material comprised ileum sections sampled from piglets ( aged 8 - 10 weeks , body weight of 15 - 18 kg ) on days 14 , 28 and 42 of the experiment . - pubmed
Although the survival of lung cancer patients has improved significantly due to the development of early detective tools , lung cancer remains a leading cause of cancer - related death after curative surgery . - pubmed
So it is extremely important for cancer patients to predict early metastasis , especially pleural dissemination , the most frequent type of recurrence in patients after surgery . - pubmed
During the median 27 months of postoperative surveillance , 16 of the 81 patients died , and 9 of the 16 developed pleural metastases . - pubmed
Epidemiology is the study of the causes and distributions of diseases in human populations so that we may identify ways to prevent and control disease . - pubmed
Economic study : a cost - effectiveness analysis of an intraoperative compared with a preoperative image - guided system in lumbar pedicle screw fixation in patients with degenerative spondylolisthesis . - pubmed
In this article , we present a long - term observation of a patient with Goldenhar syndrome . - pubmed
Altered expression of glial and synaptic markers in the anterior hippocampus of behaviorally depressed female monkeys . - pubmed
We reported reduced neuropil volume and number of glia in the dentate gyrus ( DG ) and cornu ammonis ( CA)1 of the anterior hippocampus in behaviorally depressed adult female cynomolgus macaques . - pubmed
OBJECTIVE : To study the impact of tamoxifen on overall survival ( OS ) compared to best supportive care ( BSC ) in Egyptian patients with advanced HCC . - pubmed
CONCLUSIONS : Tamoxifen did not show any OS advantage in Egyptian patients with advanced HCC . - pubmed
We describe a 62 - year - old male who was suffering from advanced prostatic malignancy , taking amiodarone for underlying heart disease . - pubmed
We have shown that , after severe trauma , obese Zucker ( OZ ) rats , similar to obese patients , exhibit increased acute lung injury compared with lean Zucker ( LZ ) rats . - pubmed
We hypothesized that OZ rats exhibit a greater increase in early posttrauma glucose compared with LZ rats , with the increased posttrauma hyperglycemia suppressed by ICI treatment . - pubmed
Orthopedic trauma was applied to both hindlimbs in LZ and OZ rats . - pubmed
Lung wet - to - dry weight ratios were increased in OZ rats but not in LZ rats . - pubmed
showed that the amount of circulating TEMs is higher in hepatitis virus C ( HCV)/HCC patients compared to HCV patients or healthy subjects . - pubmed
DESIGN : This was a crossover feeding study in 11 CKD participants ( estimated glomerular filtration rate : 30 - 45 mL min(-1 ) 1.73 m(-2 ) ) and 4 healthy control subjects . - pubmed
RESULTS : In CKD participants who consumed the high - phosphate diet , there were circadian changes in phosphate with lowest concentrations ( + - SDs ) at 0800 ( 4.2 + - 0.5 mg / dL ) and 2 peaks at 1600 and 0400 ( 4.5 + - 0.8 and 4.4 + - 0.6 mg / dL , respectively ) , which were similar to those in healthy controls . - pubmed
Unencapsulated Streptococcus pneumoniae from conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster . - pubmed
Streptococcus pneumoniae , an inhabitant of the upper respiratory mucosa , causes respiratory and invasive infections as well as conjunctivitis . - pubmed
Here we perform a comparative genomic analysis of 271 strains of conjunctivitis - causing S. - pubmed
These findings suggest that the unencapsulated strains capable of causing conjunctivitis utilize a pathogenesis strategy substantially different from that described for S. - pubmed
Radiofrequency catheter ablation of atrial fibrillation in patients with chronic obstructive pulmonary disease : opportunity and challenge : response to Dr. Kumar 's comment . - pubmed
Regulation of gene expression in HBV- and HCV - related hepatocellular carcinoma : integrated GWRS and GWGS analyses . - pubmed
OBJECTIVES : To explore the molecular mechanism of hepatitis B virus - related and hepatitis C virus - related hepatocellular carcinoma , samples from hepatitis B virus and hepatitis C virus infected patients and the normal were compared , respectively . - pubmed
CONCLUSION : The analysis above helped us to understand the pathogenesis of hepatitis B virus and hepatitis C virus associated hepatocellular carcinoma . - pubmed
METHODS : Patients with inguinal / femoral hernias from February 2013 to February 2014 undergoing SILTEP herniorraphy with telescopic dissection were compared with patients who had previously undergone SILTEP herniorraphy with balloon dissection . - pubmed
METHODS : This prospective interventional study enrolled 14 patients ( 18 eyes ) with progressive keratoconus who underwent CXL with an ultraviolet - A irradiation intensity of 18 mW / cm for 5 minutes . - pubmed
RESULTS : No intraoperative or postoperative complications were observed in any of the patients . - pubmed
Since there are concerns regarding HAART - mediated onset of cardio - metabolic diseases in the long - term , we evaluated the anthropometric profile of black HIV - infected individuals in a peri - urban setting ( Western Cape , South Africa ) . - pubmed
METHODS : This was a retrospective study of 160 subjects with CMT who had undergone neck MRI at the age of 48 months or younger at a tertiary medical center . - pubmed
, ratios of area and intensity , may provide a guideline for deciding the need for surgical intervention in CMT patients . - pubmed
METHODS : This was a nested case - control study of women who had undergone second - trimester screening for fetal aneuploidy and had banked serum available for analysis . - pubmed
RESULTS : We identified 51 cases of severe preeclampsia from our population of 3,992 women ( 1.3 % ) , of whom 33 had sufficient serum for analysis . - pubmed
Median paraxanthine concentrations were not significantly higher in women in the control group than women in the case group ( 96.4 ng / mL compared with 38.0 ng / mL , P=.12 ) , and higher serum paraxanthine was not associated with lower odds of severe preeclampsia ( odds ratio [ OR ] 0.72 , confidence interval [ CI ] 0.48 - 1.08 ) . - pubmed
Different members of the Mycobacterium genus have evolved to cause tuberculosis in diverse human populations and in a variety of animal species . - pubmed
bovis strain that is able to transmit between humans or polymorphisms in M. - pubmed
Whole genome sequencing identifies circulating Beijing - lineage Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak . - pubmed
Here we report the first whole genome sequencing of Central American Beijing - lineage strains of Mtb . - pubmed
Transplantation of olfactory ensheathing cells promotes partial recovery in rats with experimental autoimmune encephalomyelitis . - pubmed
METHODS : EAE models were established by guinea pig spinal cord homogenate ( GPSCH ) immunization in Lewis rats . - pubmed
OECs were purified and cultured from the olfactory nerve layer of SD rats , and then transplanted to the EAE models through the vena caudalis ( Group A ) or into the lateral cerebral ventricle ( Group B ) . - pubmed
Neurological function scores and body weights were daily recorded following transplantation , and histological analysis was performed to assess the pathological changes in EAE rats . - pubmed
Neurological function scoring and the body weight measurement showed that , OEC transplantation could significantly improve the performance of EAE rats , and similar results were observed for the transplantation through the vena caudalis and into the lateral cerebral ventricle . - pubmed
Moreover , the transplanted OECs accumulated to the lesions in the brains of EAE rats , in spite of the different transplantation approaches . - pubmed
METHODS : Case - control study of 112 patients with advanced ovarian cancer submitted to chemotherapy during the period from January 1995 to December 2005 . - pubmed
Nondiabetic kidney diseases in type 2 diabetic patients . - pubmed
BACKGROUND : The aim of this study was to evaluate the clinical characteristics of nondiabetic nephropathy in type 2 diabetes mellitus patients and to find a clinical significance of renal biopsy and immunosuppressive treatment in such a patient . - pubmed
METHODS : Renal biopsy results , clinical parameters , and renal outcomes were analyzed in 75 diabetic patients who underwent kidney biopsy at Chungnam National University Hospital from January 1994 to December 2010 . - pubmed
CONCLUSION : Renal biopsy should be recommended for type 2 diabetic patients with atypical nephropathy because a considerable number of these patients may have nondiabetic nephropathies . - pubmed
And intensive treatment including corticosteroid or immunosuppressants could be recommended for type 2 diabetic patients with nondiabetic nephropathy , especially if the patients do not have diabetic retinopathy . - pubmed
The primary endpoint was mortality , after exclusion of patients with metastatic cancer during follow - up . - pubmed
Previous studies have revealed that treatment with BM - MSCs may modulate immune responses and alleviate the symptoms in experimental autoimmune encephalomyelitis ( EAE ) mice , an animal model of multiple sclerosis . - pubmed
Following three passages , BM - MSCs were injected intraperitoneally into EAE mice alone or in combination with rapamycin . - pubmed
Maternal Obesity in the Mouse Compromises the Blood - Brain Barrier in the Arcuate Nucleus of Offspring . - pubmed
Effect of Electroacupuncture on Inflammation in the Obese Zucker Fatty Rat Model of Metabolic Syndrome . - pubmed
Metabolic syndrome ( MetS ) is a major and escalating public health and clinical challenge worldwide , and patients with MetS have an increased risk of developing cardiovascular disease and type 2 diabetes mellitus . - pubmed
Electroacupuncture ( EA ) was tested as a means of decreasing inflammation in genetically obese Zucker fatty rats , which serve as a model of MetS. - pubmed
Compared with the control animals , no significant change in body weight occurred . - pubmed
Modeling lymphangiosarcoma in mice . - pubmed
Patients were divided into two groups : with atherosclerosis and without . - pubmed
PATIENTS AND METHODS : Forty patients with mucinous appendiceal tumors and PMP were clinically eligible and had evaluable tumor samples obtained after CRS and HIPEC . - pubmed
RESULTS AND CONCLUSION : On 2 days after cessation of CCl4 administration , higher fibrosis was observed in KO mice than in WT mice by Sirius Red staining . - pubmed
Hydroxyproline contents and Sirius Red staining showed that repair of liver fibrosis in the recovery stages appeared to be delayed in KO mice . - pubmed
Among the many stilbenoids found in a variety of berries , resveratrol and pterostilbene are of particular interest given their potential for use in cancer therapeutics and prevention . - pubmed
Breast cancer ( BC ) is the most common female malignancy within the spectrum of human cancer . - pubmed
Patients with a higher NLR had a shorter disease - free survival ( hazard ratio = 1.46 , 95 % confidence interval : 1.12 - 1.90 , P=0.044 ) and overall survival ( hazard ratio = 2.03 , 95 % confidence interval : 1.41 - 2.93 , P<0.001 ) . - pubmed
In the luminal A and luminal B subtypes , we found that there was no association between the NLR and overall survival in the BC patients . - pubmed
Utility and safety of tolvaptan in cirrhotic patients with hyponatremia : A prospective cohort study . - pubmed
Hyponatremia is common in patients with decompensated cirrhosis and is associated with increased mortality . - pubmed
MATERIAL AND METHODS : We studied the usage and safety of tolvaptan in cirrhotic patients in a real - life , non - randomized , multicenter prospective cohort study . - pubmed
Forty - nine cirrhotic patients with hyponatremia were treated with tolvaptan 15 mg daily , and 48 patients not treated with tolvaptan in the same period served as controls . - pubmed
No patient with normal serum sodium on day 7 died within 30 days of treatment , whereas 16 % of those with persistent hyponatremia died ( p = 0.0019 ) . - pubmed
CONCLUSION : In conclusion , short - term tolvaptan treatment is safe and can improve serum sodium level in cirrhotic patients with hyponatremia . - pubmed
Enhancer of polycomb coordinates multiple signaling pathways to promote both cyst and germline stem cell differentiation in the Drosophila adult testis . - pubmed
Six of the 25 patients died after AMI . - pubmed
In addition , 10 of the 25 patients developed in - hospital AMI after surgery . - pubmed
Thus the strain isolated from the Dokdo Island is proposed as a novel species , Tetramitus dokdoensis n. sp . - pubmed
The role of hydrogen sulfide ( H2S ) in portal hypertension ( PH)-induced esophagus - gastric junction vascular lesions in rabbits was observed . - pubmed
T - Cell Mediation of Pregnancy Analgesia Affecting Chronic Pain in Mice . - pubmed
Using an inflammatory ( complete Freund 's adjuvant ) or neuropathic ( spared nerve injury ) model of persistent pain , we observed that young adult female mice in early pregnancy switch from a microglia - independent to a microglia - dependent pain hypersensitivity mechanism . - pubmed
During late pregnancy , female mice show no evidence of chronic pain whatsoever . - pubmed
This pregnancy - related analgesia has been demonstrated for acute pain in rats . - pubmed
Here , we show that pregnancy analgesia can produce a complete cessation of chronic pain behaviors in mice . - pubmed
Changes in Signal Intensity of the Dentate Nucleus and Globus Pallidus in Pediatric Patients : Impact of Brain Irradiation and Presence of Primary Brain Tumors Independent of Linear Gadolinium - based Contrast Agent Administration . - pubmed
Materials and Methods This institutional review board - approved , HIPAA - compliant study included 144 pediatric patients who underwent intravenous GBCA - enhanced MR imaging examinations ( 55 patients with primary brain tumors and whole - brain irradiation , 19 with primary brain tumors and chemotherapy only , 52 with primary brain tumors without any treatment , and 18 with neuroblastoma without brain metastatic disease ) . - pubmed
Hafnia alvei : A new pathogen in open fractures . - pubmed
Hafnia alvei is an unusual pathogen that is rarely pathogenic in humans and has never been reported as a cause of infection following open fracture . - pubmed
Conclusions : This is the first report of deep infection following an open forearm fracture owing to Hafnia alvei , a pathogen rarely responsible for human infection . - pubmed
A few drugs and drug combinations are used in the treatment of canine babesiosis often without complete parasite elimination leaving treated dogs as carriers which could relapse with clinical disease and also transmit infection further . - pubmed
Zebrafish Models of Rare Hereditary Pediatric Diseases . - pubmed
A plethora of genetic tools makes it easy to create mutations in almost any gene of the zebrafish genome and these mutant strains can be used in high - throughput preclinical screens for active molecules . - pubmed
A total of 768 1 - d - old Ross 308 male broiler chickens with an average body weight of 43.64 + - 0.59 g were used in a 5 - wk feeding trial . - pubmed
During sepsis , disturbed gastrointestinal motility and increased mucosal permeability can aggravate sepsis due to the increased risk of bacterial translocation . - pubmed
To help identify new therapeutic targets , there is a need for animal models that mimic the immunological changes in the gastrointestinal tract as observed during human sepsis . - pubmed
Brachycephalic airway syndrome ( BAS ) is characterized by increased upper airway resistance due to conformational abnormalities occurring in brachycephalic dogs ( BD ) . - pubmed
In this prospective study , we evaluated pulse oximetry ( SpO2 ) and arterial blood gas values in 18 healthy BD and compared these values with those of 18 healthy mesocephalic and dolichocephalic dogs ( MDD ) . - pubmed
PATIENTS AND METHODS : We performed a retrospective analysis of the data of 319 patients [ 123 ( 36.6 % ) female and 196 ( 61.4 % ) male ] who had colorectal cancer and underwent surgery to treat colorectal liver metastases in our Department between 2005 and 2014 . - pubmed
METHODS : Twenty - five subjects with anterior mediastinal lesions suspicious for malignancy were enrolled in an open - label feasibility trial . - pubmed
Among the subjects with solid tumors , 19 of 20 accumulated ICG . - pubmed
METHODS : A total of 50 consecutive patients with pancreatic / periampullary cancer who underwent PD between January 2016 to August 2017 were included in the study . - pubmed
The aim of this study was to evaluate the agreement of EDX and MRI in patients with brachial plexopathy . - pubmed
DESIGN : The records of 69 patients with symptoms of brachial plexopathy who underwent EDX and MRI were reviewed . - pubmed
MATERIALS AND METHODS : The study was carried out in vac - cine strain Y pestis EV76 ( pMT1 , pCD1 , pPCP1 ) and non - plasmid variants of vaccine EV76 ( pMT1- , pCD1- , pPCP1- ) and virulent 231 ( pMT1- , pCD1- , pPCP1- ) strains of Y pestis . - pubmed
Presence of functionally active form of lipopolysaccharide ( LPS ) in.the incubation medium of the bacteria was evaluated via toxicity of supernatant of Y pestis for intactanimals ( infec- tion - toxic shock ) and mice sensitized by D - GalN. - pubmed
Non - plasmid variants of both vaccine and virulent strains of Y.pestis pMT- , pCD1- , pPCP1- do not have this ability . - pubmed
Individuals with end - stage diabetic peripheral neuropathy present with decreased pain sensation . - pubmed
Myocardial extracellular volume fraction measurements with MOLLI 5(3)3 by cardiovascular MRI for the discrimination of healthy volunteers from dilated and hypertrophic cardiomyopathy patients . - pubmed
RESULTS : DCM and HCM patients had significantly higher myocardial native T1 times and ECVs than healthy volunteers ( p<0.001 ) . - pubmed
At the optimal cut - off value , ECV identified DCM and HCM patients with 80.7 % and 83.3 % sensitivity , 87.5 % and 70 % specificity , 90.2 % and 67.6 % positive predictive value , and 76.1 % and 84.8 % negative predictive value , respectively . - pubmed
This study aimed to investigate whether the number of LSAs was associated with the cerebral perfusion in SVD patients and determine the correlation between the number of LSAs and SVD severity . - pubmed
Conclusion : LSA count was lower in SVD patients than the non - SVD participants and there was a positive correlation between the cerebral perfusion and the number of LSAs . - pubmed
This finding may have potentially important clinical implications for monitoring LSA in SVD patients . - pubmed
Previously , we used a computational biology approach to define molecular signatures of antiviral DC responses following activation of innate immune signaling or infection with West Nile virus ( WNV ) . - pubmed
Strains of B. - pubmed
Type strains of Bacillus halotolerans and Bacillus mojavensis were grouped into another cluster ( cluster B ) , related to cluster A. - pubmed
Older patients showed a lower frequency of FUTI caused by E. - pubmed
Corneal Refractive Surgery in Patients with History of Optic Neuritis . - pubmed
Purpose : The purpose of this study was to evaluate the risk of recurrence of optic neuritis after corneal refractive surgery in patients with a history of optic neuritis and to examine the safety and efficacy of the procedure in this population . - pubmed
Patients were followed - up for over five years postoperatively for the recurrence of optic neuritis . - pubmed
Optic neuritis recurred in 3/15 ( 20 % ) eyes and 3/14 patients ( 21 % ) . - pubmed
Conclusion : While corneal refractive procedures appear safe in patients with a history of optic neuritis , our data suggest that their efficacy may be reduced . - pubmed
Pleomorphic xanthoastrocytoma ( PXA ) is a relatively rare , low grade astrocytic tumor that usually affects children as well as young adults . - pubmed
PURPOSE : To evaluate different corneal parameters in identifying patients at risk of a hyperopic shift after ( DMEK ) . - pubmed
METHODS : This retrospective study included 92 eyes of patients with FECD after DMEK surgery . - pubmed
In total , 48 girls with CPP and 35 age - matched prepubertal control girls were enrolled in the study . - pubmed
Diabetic nephropathy ( DN ) is one of the leading causes of mortality in diabetic patients . - pubmed
Occurrence of Leaf Spot Disease Caused by Alternaria crassa ( Sacc . ) - pubmed
was recovered from jimson weed , tomato , parsley , and coriander collected during surveys of blight diseases on Solanaceae and Apiaceae in Algeria . - pubmed
Further the pathogen was evaluated on jimson weed , coriander , parsley , and tomato plants , and this fungus was able to cause necrotic lesions on all inoculated plants . - pubmed
The risk factors associated with local recurrence ( LR ) in patients receiving preoperative denosumab for GCTB also are unknown . - pubmed
QUESTIONS / PURPOSES : ( 1 ) Is short - course ( three doses or fewer ) preoperative denosumab treatment as effective as longer course ( more than three doses ) of treatment in terms of achieving a clinical , radiologic , and histologic response in patients with GCTB ? - pubmed
( 2 ) Is there an increased risk of LR after short - course denosumab therapy compared with long - course denosumab therapy ; and after controlling for confounding variables , what factors were associated with LR after surgery for GCTB in patients receiving preoperative denosumab ? - pubmed
METHODS : A retrospective study was performed using an institutional database of 161 skeletally mature patients with a histologic diagnosis of GCTB who received denosumab between November 2010 and July 2019 to downstage the tumor before surgery . - pubmed
In general , we used denosumab when we thought it would facilitate either resection or curettage ( by formation of a sclerotic rim around the osteolytic lesion ) , when a less - morbid procedure than initially planned might be performed , and in patients with complex presentations like cortical breech and soft tissue extension , pathological fracture , thinning of more than three cortices of the extremity . - pubmed
Overall , 77 % ( 37 of 48 ) of patients taking short - course denosumab and 75 % ( 27 of 36 ) of patients on long - course denosumab underwent curettage , and the remaining patients with an inadequate bony shell around the tumor or destruction of articular cartilage in both groups underwent tumor resection . - pubmed
With the numbers available , the patients with short- and long - course denosumab were not different in terms of age , sex , MSTS score on presentation , lesion size , lesion location , Campanacci grade , presence of pathological fracture and pulmonary metastasis on presentation , and the type of surgery performed ( curettage versus resection ) . - pubmed
We recruited a subsample of 45 children ( mean age 9y 2mo ; SD 2y 7mo ; range 5 - 12y ; 22 males , 23 females ) and collected parental reports of autism symptomatology , adaptive behavior , and behavioral problems that were compared to those of 360 age- and sex - matched controls from the Simons Simplex Collection ( SSC ) with autism spectrum disorder ( ASD ; SSC - ASD ) or typically developing ( SSC - TD ) . - pubmed
Immunotherapy has recently emerged as a promising treatment option for multiple myeloma ( MM ) patients . - pubmed
Thus , further characterization of the defects present in the immune system of MM patients is essential to develop novel therapies and to repurpose the existing ones . - pubmed
In the patient discussed , hyperflexion of the hip results in the engagement of the present CAM lesion , and the resulting subluxation leads to a fracture of the posterior wall and instability of the hip . - pubmed
OBJECTIVES : To define pre - morbid , clinical , laboratory , and imaging features and identify prognostic factors associated with morbidity and mortality in patients with Emphysematous pyelonephritis ( EPN ) and develop a prognostic scoring system for improving management outcomes . - pubmed
BA01 , a gut bacterial strain of the wood ant ( Formica yessensis ) . - pubmed
METHODS : This retrospective , longitudinal cohort study included consecutive patients with primary SS evaluated at a tertiary referral center . - pubmed
RESULTS : One hundred and twenty - six SS patients with minimum 3 years of follow - up ( median 9.6 , range 3.0 - 15.9 years , total of 1,235 patient - years ) were included . - pubmed
The type strains of Rhodocytophaga rosea and Nibribacter ruber are 172606 - 1 T (= KCTC 62096 T = NBRC 114410 T ) and BT10 T (= KCTC 62607 T = NBRC 114383 T ) , respectively . - pubmed
MATERIALS AND METHODS : The extension of six textural features , including consolidation ( C ) , ground glass opacity ( GGO ) , fibrosis ( F ) , low attenuation areas ( LAA ) , reticulation ( R ) and healthy regions ( H ) , was quantified in 27 cHP patients ( age : 56 + - 11.5 years , forced vital capacity [ FVC]% = 57 + - 17 ) acquired at full - inspiration via HRCT . - pubmed
Some miRNAs have already been found to be closely related to the prognosis of patients with OS . - pubmed
While the proportion of ischemic stroke patients recommending endovascular treatment ( 14.3 % vs. 14.6 % ; p=0.85 ) remained stable , there was a non - significant trend towards a lower proportion of recommending intravenous thrombolysis during the lockdown ( 19.0 % vs. 22.1 % ; p=0.052 ) . - pubmed
However , the influence of DAAs on the course of kidney involvement in HCV - associated mixed cryoglobulinaemia ( HCV - MC ) has been little studied . - pubmed
The aim of this study was to analyse the effects of antiviral treatment on kidney prognosis and evolution in patients diagnosed with HCV - MC . - pubmed
Methods : The RENALCRYOGLOBULINEMIC study is an observational multicentre cohort study of 139 patients with HCV - MC from 14 Spanish centres . - pubmed
Provided optimal conditions are employed the microtest system described herein should be ideal for in - vitro - analysis of inhibitory or stimulating factors in cancer patients ' sera . - pubmed
Complement - dependent antibody cytotoxicity test of chicken antibody with duck complement used against cells of a Marek ' s disease lymphoma - derived cell line ( MSB-1 ) . - pubmed
Complement - dependent antibody cytotoxicity ( CDAC ) against cells of a lymphoblastoid cell line ( MSB-1 ) derived from Marek ' s disease lymphoma was investigated in a chicken antibody system using complements from several animal species . - pubmed
Cytotoxicity was seldom observed when rabbit , guinea pig , or chicken complements were used in the presence of hyperimmune chicken serum against MSB-1 . - pubmed
With duck complement , however , cytotoxicity was always observed . - pubmed
A study of acute hemiplegia in children . - pubmed
The initial rate of phagocytosis , oxygen consumption rate during phagocytosis , bactericidal capacity against Escherichia coli , and the granule protein composition of isolated mature - appearing granulocytes were studied in 23 patients with chronic granulocytic leukemia ( CGL ) with the simultaneous use of normal controls . - pubmed
The initial rate of phagocytosis was decreased ( p less than 0.05 ) in the CGL patient group , as were oxygen consumption rate ( p less than 0.001 ) and bactericidal capacity ( p less than 0.001 ) . - pubmed
Functional disturbances due to herpetic keratouveitis in rabbits were investigated . - pubmed
This experimental herpetic keratouveitis in rabbits appeared similar to Wellings ' ocular syndrome , which is suspected to be of herpetic etiology . - pubmed
The authors report a 16 - year - old girl with mucolipidosis type IV . - pubmed
However , the presence of titanium III citrate or dithiothreitol ( 7.78 mM ) in the medium decreased ( P less than 0.05 ) the leukotoxicity of F. - pubmed
Of the 720 patients with thyroid cancer we saw from 1953 to 1989 , 49 were younger than 20 years at diagnosis , and the female / male ratio was 4.4:1 . - pubmed
Suspected vitamin D rodenticide poisoning in a dog . - pubmed
Chickens passively inoculated with these antibodies were protected against bursal atrophy , weight loss , and early mortality when challenged with the virulent Md5 strain of Marek ' s disease virus ( MDV ) . - pubmed
This result provides little hope that Marek ' s disease can be controlled in progeny chickens by maternal immunity derived from hyperimmunized parents . - pubmed
The mechanism of hypocalcemia was assessed prospectively in 10 gastroenterological hypomagnesemic patients . - pubmed
In the 4 tested patients , plasma 1,25 ( OH ) 2D levels were low before , but also after correction of hypomagnesemia , suggesting that low level of 1,25 ( OH ) 2D might not be due to hypomagnesemia . - pubmed
Therefore , treatment with low dosage of 1 - alpha ( OH ) 2D associated with magnesium chloride repletion can be recommended to restore normal calcium homeostasis in patients with intestinal hypomagnesemia . - pubmed
We have evaluated the effect of 5 - fluorouracil 600 mg / m2 , doxorubicin ( ' Adriamycin ' ) 40 mg / m2 , and Mitomycin - C 4 mg / m2 ( FAM ) in two groups of patients with adenocarcinoma of the oesophagus , as either a preoperative or primary treatment . - pubmed
Resection was completed in 20 patients , with six hospital deaths ( 30 % ) . - pubmed
Of the 14 patients who were discharged from hospital , 8 have died ( median 8 months ) and 6 are alive at 12 to 27 months , with known recurrence in 1 . - pubmed
More pharmacokinetic studies are needed in human drug abuse liability evaluations . - pubmed
In our Pediatric Haemato - Oncology Unit , 42 young patients cured of their malignancy were left with chronic delta hepatitis . - pubmed
All nine patients included in the study ( five males , mean age : 15 years ) had well - compensated liver disease , including five cases with active hepatitis and cirrhosis . - pubmed
At the end of the 3rd month of therapy , two patients with cirrhosis developed a biochemical exacerbation leading to hepatic decompensation , which was fatal in one case . - pubmed
On the other hand , both patients seroconverted from hepatitis B e antigen to antibody at the time of exacerbation , suggesting that liver damage could have been the result of cell - mediated cytotoxicity to hepatitis B virus antigens . - pubmed
Occult cancer in patients with deep venous thrombosis . - pubmed
The authors prospectively studied 113 consecutive patients with deep venous thrombosis of the lower extremities to determine the most appropriate workup study for searching for a hidden cancer . - pubmed
Lung cancer and exposure to tobacco smoke in the household . - pubmed
Sera from 75 patients with warts were tested for antibodies against human papillomaviruses ( HPVs ) in an immunoelectron microscopy test . - pubmed
A group of 40 patients ' sera were tested against a pooled suspension of the HPVs extracted from their warts and 90 % of the sera were found to be antibody - positive . - pubmed
In all 9 dogs that underwent tracheal replacement with PTFE , granulation tissue developed at the anastomoses resulting in airway obstruction after 3 to 8 weeks . - pubmed
Ganglion cells were demonstrated by upper biopsy in four of 13 neonates , six of nine infants , and three of six children . - pubmed
The two - point rectal mucosal biopsy is useful not only for making definitive diagnosis but also for the selection of the surgical treatment for patients with Hirschsprung ' s disease . - pubmed
Epidemiological aspects of human cryptosporidiosis . - pubmed
Twelve patients with non - small cell lung cancer had tumors that were adherent to the vertebral column and clinically suspected of invading the bone . - pubmed
Three patients had true Pancoast ' s syndrome and in the remaining nine the tumor was located above T6 with the majority in the apex of the chest . - pubmed
Detailed studies of the decalcified surgical specimen show that the tumor extended into the cortex in two patients , periosteum in six , parietal in three , and up to the visceral pleura in one . - pubmed
Six patients are alive after 1 to 11 years ( four beyond 5 years ) without evidence of recurrent tumor and arthritic pain . - pubmed
In patients with tumors adherent to the vertebral body and no evidence of roentgenographic erosion , the en bloc removal of the lung and the involved portion of the vertebral body is required for complete excision and is associated with long - term survival without sequelae . - pubmed
The impulse activity of 177 neuronal populations analyzed in different nuclei of the thalamus and striopallidal complex during visual testing for orientation sensitivity in 9 parkinsonian patients , diagnosed and treated with the long - term intracerebral electrodes . - pubmed
Selection of protein and fat by diabetic rats following separate dilution of the dietary sources . - pubmed
Diabetic and normal rats were allowed to select their diets from separate sources of protein , carbohydrate and fat . - pubmed
Following the determination of baseline intakes , diabetic and normal rats received dietary components in which either the protein ( Experiment 1 ) or fat source ( Experiment 2 ) was diluted by 25 % or 50 % by the addition of cellulose . - pubmed
Diabetic rats failed to maintain protein intake at both dilution levels , but made up for the loss of protein - derived calories by consuming more fat . - pubmed
Diabetic rats maintained fat intake at both dilution levels . - pubmed
Dietary dilutions had no effect on total caloric intakes or body weight gain of diabetic rats . - pubmed
These data suggest that diabetic rats maintain total caloric intake following dilution of either the protein or fat source of their diets , but defend intake of fat - derived calories more readily than protein - derived calories . - pubmed
These findings are discussed in terms of the ability of diabetic rats to solve the metabolic problems associated with their diabetic condition . - pubmed
Two TaqI RFLPs in the human von Willebrand factor gene . - pubmed
The mutagenic activity of fasting gastric juice was assessed in 123 patients including 18 with normal endoscopic findings , 53 peptic ulceration , 9 gastric cancer , 12 pernicious anaemia and 31 patients who had undergone peptic ulcer surgery in the past . - pubmed
No correlation was found between mutagenic activity and patient age or sex , gastric pH , bile acid concentrations or bacterial counts , intestinal metaplasia on gastric mucosal biopsy , or intragastric nitrite . - pubmed
About 30 % of gastric juice samples showed evidence of a cytotoxic activity towards the Salmonella tester strains in the mutation assay . - pubmed
We describe the clinicopathological features of multiple hamartoma and neoplasia syndrome ( Cowden ' s syndrome ) in a 58 year - old man and in a 56 year - old woman . - pubmed
Plasmapheresis was used as a complement to conventional therapy in a patient with multiorgan failure and disseminated intravascular coagulation ( DIC ) following biliary obstruction and septic cholangitis . - pubmed
A retrospective study was conducted on 22 patients with renal pelvic tumor treated at our University Hospital between 1970 and 1984 . - pubmed
Actinobacillus actinomycetemcomitans in human periodontal disease . - pubmed
Recent evidence implicates Actinobacillus actinomycetemcomitans in the etiology of localized juvenile periodontitis . - pubmed
actinomycetemcomitans , evidence incriminating it as a periodontopathogen , its importance in human nonoral infections , and virulence factors which may be involved in the pathogenesis of A. - pubmed
The organism can apparently seed from these sites to cause severe infections throughout the human body such as brain abscesses and endocarditis . - pubmed
actinomycetemcomitans as an important micro - organism in the etiology of localized juvenile periodontitis including : ( 1 ) an increased prevalence of the organism in almost all localized juvenile periodontitis patients and their families compared to other patient groups ; ( 2 ) the observation that localized juvenile periodontitis patients exhibit elevated antibody levels to A. - pubmed
actinomycetemcomitans in serum , saliva and gingival crevicular fluid ; ( 3 ) the finding that localized juvenile periodontitis can be successfully treated by eliminating A. - pubmed
actinomycetemcomitans from periodontal pockets ; ( 4 ) histopathologic investigations showing that A. - pubmed
actinomycetemcomitans invades the gingival connective tissue in localized juvenile periodontitis lesions ; ( 5 ) the demonstration of several pathogenic products from A. - pubmed
Virulence of Pseudomonas infection in burned rats and mice . - pubmed
[ Oxidative phosphorylation in the brain of rabbits with atherosclerosis ] . - pubmed
On the site of action of nicotine on contracture in frog sartorius muscle . - pubmed
When tested in kindled animals , both agents showed a transient and non - dose - dependent anticonvulsant effect , in addition to raising the generalized convulsive seizure - triggering threshold for a prolonged period of time . - pubmed
Neuronotrophic activities in cerebrospinal fluid of head trauma patients . - pubmed
Cerebrospinal fluid was collected from 15 patients with acute CNS lesions in whom ventricular catheters had been placed to monitor and to facilitate the control of intracranial pressure . - pubmed
NTFs supporting hippocampal neurons were also detected in extracts of blood clot obtained from normal volunteers . - pubmed
These observations suggested that ( i ) NTFs are detectable in human CSF after CNS injury , ( ii ) NTFs appear in response to the injury itself , and ( iii ) at least some human NTFs can support the survival in culture of nonhuman CNS neurons . - pubmed
The anemia of chronic renal failure in sheep . - pubmed
To determine the in vivo relevance of uremic inhibitors , increasing amounts of Ep as Ep - rich plasma were infused into six uremic sheep , and their erythropoietic responses were compared with those of nine normal sheep receiving similar amounts of Ep - rich plasma . - pubmed
Three sheep were studied in both normal and uremic states . - pubmed
Ep - rich plasma was obtained from phenylhydrazine- and phlebotomy - induced anemic sheep . - pubmed
Ep - rich plasma stimulated erythropoiesis similarly in uremic and normal sheep , regardless of the degree of uremia . - pubmed
Nondialyzed uremic sheep responded as well as dialyzed animals . - pubmed
The anemia was corrected in the uremic dialyzed animals . - pubmed
The anemia was corrected in the uremic sheep after 15 - 40 daily infusions of Ep - rich plasma , the total dosage depending on the severity of the anemia . - pubmed
These dose - response effects , coupled with the identical erythropoietic response in normal and uremic sheep given the same amount of Ep - rich plasma , imply that there are no physiologically significant erythropoietic inhibitors in uremia . - pubmed
In comparison with control animals ( pCO2 = 41.2 mm Hg ) , the d / D ratio in animals with hypercapnia ( pCO2 = 69.9 mm Hg ) was increased by 11.7 % in the pial arteries and 7.9 % in the cortical arteries , indicating vasodilatation . - pubmed
The pathogenesis of ischaemic neuronal damage along the cerebral arterial boundary zones in Papio anubis . - pubmed
The pathogenesis of ischaemic neuronal damage along the arterial boundary zones of the forebrain was investigated in 20 lightly anaesthetized , spontaneously breathing baboons . - pubmed
Additional occlusion of the left common carotid artery for 20 min had no effect on the EEG ( except for one animal with a cerebrovascular anomaly ) . - pubmed
The brains of 3 animals were normal and in the 15 with brain damage this was restricted in the cerebral cortex to the arterial boundary zones . - pubmed
Calcification and crystallization in bovine enamel . - pubmed
Are animal models suitable for the study of ischemic heart disease ? - pubmed
Of 11 patients with degenerative changes in the distal radio - ulnar joint on preoperative X - ray , 8 stated they were helped by the operation , while of 13 patients without any signs of arthrosis in the distal radio - ulnar joint , only 4 experienced relief of their discomfort . - pubmed
A total of 110 children , aged 0 - 15 years , were investigated for circulating megakaryocytes in cubital venous blood using the saponin - haemolysis leucoconcentration technique . - pubmed
Excitatory movements and hypertonus occurred in seven patients during operation and in ten patients in the early recovery phase . - pubmed
The latter was significantly depressed in the tumor - bearing animals as compared to the corresponding saline - injected controls . - pubmed
Event - related potentials ( ERPs ) to visual and somatosensory stimuli , generated during an oddball task , were obtained in a group of autistic children and 3 control groups ( normal , attention - deficit , and dyslectic children , respectively ) . - pubmed
Research questions were whether ( a ) autistic children differ from other children with respect to the processing of visual and/or somatosensory stimuli , as measured in the amplitude of the N1 , mismatch activity , and P3 , ( b ) autistic children specifically have problems in the processing of distal ( visual ) stimuli , compared to the processing of proximal ( somatosensory ) stimuli , and ( c ) autistic children have an atypical lateralization pattern of ERP activity . - pubmed
BACKGROUND : We describe a recently observed set of autosomal dominant GEMSS ( glaucoma , lens ectopia , microspherophakia , stiffness of the joints , and shortness ) syndrome in a 47 - year - old woman and her 23 - year - old son . - pubmed
In addition , sclerosis of the skin , from which both patients suffered , is investigated in detail . - pubmed
The estimated blood loss ( 873 + /- 484 ml ) and the preoperative hematocrit ( 33.4 % + /- 6.4 % ) in the women who did not receive transfusion were not significantly different from those of patients who received packed red blood cells ( 854 + /- 576 ml and 30.0 % + /- 5.4 % , respectively ) . - pubmed
Pelvic actinomycosis is a rare disorder caused by Gram - positive anaerobic bacteria Actinomyces Israeli , and it is commonly associated with the prolonged use of IUD . - pubmed
The ALL-1 gene , located on chromosome band 11q23 , is fused to a variety of other genes by reciprocal chromosomal translocations present in 5 - 10 % of human acute leukemias . - pubmed
METHODS : Measurements of hemostatic function and metabolic and angiographic indicators of risk were included in a prospective cohort study of variables predictive of reinfarction , cardiac death and major coronary events within 6 to 9 years in 108 unselected nondiabetic men with a first myocardial infarction before age 45 years . - pubmed
RESULTS : During follow - up , 20 patients had sudden cardiac death , and 53 had a major coronary event ( reinfarction , sudden cardiac death , bypass surgery or intervention by catheterization ) . - pubmed
Subsequent Bowen ' s disease occurred in eight patients ( 11.3 % ) . - pubmed
Twenty - six patients ( 36.6 % ) had concurrent skin cancers , either basal cell carcinoma or squamous cell carcinoma , or both . - pubmed
By crossing the complex - glycan - deficient strain of A. - pubmed
Lysophosphatidylcholine accumulates in the coronary sinus during pacing - induced myocardial ischemia in humans . - pubmed
This amphiphile accelerates Ca ++ flux leading to cell injury in cultured cardiac myocytes , but it is not known whether lysophosphatidylcholine accumulation is injurious to human myocardium . - pubmed
We conclude that lysophosphatidylcholine accumulation is a marker of myocardial ischemia in humans . - pubmed
In two consecutive studies , 80 subjects human immunodeficiency virus ( HIV)-1 - seropositive ( 21 asymptomatic , 6 persistent generalized lymphadenopathy , 13 AIDS - related complex , and 40 AIDS ) were examined for oral lesions . - pubmed
In the second study of 25 patients , HIV was detected in plasma of 56 % ( titers , 1/10 to & gt ; 1/1000 ) but not in diluted saliva supernatants , even in those with severe periodontal disease . - pubmed
Hence , infectious HIV and DNA was found at very low concentrations in 21 % and 28 % of HIV - seropositive patients , respectively , at all stages of HIV infection . - pubmed
Assessment of the efficacy of an antibiotic drug used in patients with various manifestations of dermatoborreliosis is crucial . - pubmed
It was intended to establish a constant parameter -- besides the clinical picture -- for assessing the efficacy of antibiotic treatment in patients with dermatoborreliosis in terms of eradication of Borrelia burgdorferi from the site of infection . - pubmed
burgdorferi - specific DNA was amplified by PCR in 23/36 erythema migrans patients ( 69 % ) , and in 5/7 acrodermatitis chronica atrophicans patients ( 71 % ) . - pubmed
However , patients with steatosis had serum mass concentrations of this enzyme significantly lower ( mean 2 - 3 fold ) than those measured in cancer patients ( P & lt ; 0.05 ) or cirrhotic patients ( P & lt ; 0.001 ) . - pubmed
[ Superior sagittal sinus thrombosis in children during the first year of life : clinical aspects , imaging and development ] . - pubmed
PATIENTS : From 1988 to 1994 , 11 children had cerebral venous thrombosis ( longitudinal sinus ) in the first year of their life . - pubmed
METHODS : Eighteen anaesthetized dogs underwent progressive isovolaemic haemodilution with either HES ( group 1 ) or UPBH ( group 2 ) to haematocrit target levels of 15 , 10 and & lt ; 5 % . - pubmed
One dog without haemodilution figured as control animal . - pubmed
In contrast , HES - treated animals showed severe histological changes of renal tubuli caused by isovolaemic anaemia . - pubmed
The target level of LDL - cholesterol is less than 1.30 g / l in patients with known coronary heart disease . - pubmed
Therefore these , patients with a MGUS and clinical deterioration despite conventional immunosuppressive treatment should undergo large - scale diagnostic check - up to make sure that the chance for an adequate chemotherapy is taken . - pubmed
Mechanisms underlying stimulation of rapidly adapting receptors during pulmonary air embolism in dogs . - pubmed
Clear cell " sugar " tumor of the lung : association with lymphangioleiomyomatosis and multifocal micronodular pneumocyte hyperplasia in a patient with tuberous sclerosis . - pubmed
We report the unique association of a clear cell " sugar " tumor of the lung ( CCTL ) in a 32 - year - old woman with tuberous sclerosis ( TSC ) , lymphangioleiomyomatosis ( LAM ) , and multifocal micronodular pneumocyte hyperplasia ( MMPH ) . - pubmed
Early assessment of patients with suspected acute myocardial infarction by biochemical monitoring and neural network analysis . - pubmed
Eighty - eight patients admitted within 8 h after onset of chest pain were included . - pubmed
It gives documented good patient satisfaction , range of motion , pain relief and relatively few serious complications . - pubmed
In animal and human models , left ventricular ( LV ) diastolic function has been observed to be highly sensitive to myocardial ischemia . - pubmed
Eight mongrel dogs , in which were inserted a high - fidelity micromanometer LV catheter , coronary sinus sampling catheter , and ultrasonic coronary artery flow probe , underwent intravenous dobutamine infusion at escalating doses both before ( control protocol ) and after ( ischemia protocol ) creation of left anterior descending coronary artery stenosis with a hydraulic cuff occluder adjusted to maintain resting coronary artery flow but attenuate reactive hyperemia . - pubmed
Immunophenotyping of acute lymphoblastic leukemia in pediatric patients by three - color flow cytometric analysis . - pubmed
Stapled versus sutured gastrointestinal anastomoses in the trauma patient . - pubmed
To date , no study has evaluated the incidence of complications of stapled anastomoses in the trauma patient . - pubmed
CONCLUSION : Anastomotic leaks seem to be associated with stapled bowel repairs compared with sutured anastomoses in the traumatically injured patient . - pubmed
On the first day of pregnancy , diabetes was induced by intravenous administration of streptozotocin in half the animals from the two diet groups . - pubmed
Left ventricular hypertrophy ( LVH ) , a target - organ response to chronic pressure or volume overload , is associated with its own independent risks of death in patients with hypertension . - pubmed
Preclinical and early human studies of calcium and colon cancer prevention . - pubmed
Normal mouse and rat strains as models for age - related cataract and the effect of caloric restriction on its development . - pubmed
The purpose of this study was to determine : ( 1 ) which of the commonly used strains of laboratory rats and mice provide good models for human age - related cataract , and ( 2 ) whether long term caloric restriction , a regimen that prolongs both median and maximum life span in rodents , would also delay the time of appearance of this age - related pathology . - pubmed
These strains were Brown Norway and Fischer 344 rats , and C57BL/6 , ( C57BL6 x DBA/2)F1 and ( C57BL/6 x C3H)F1 mice . - pubmed
Various stages of cataract were found in the great majority of these animals in old age . - pubmed
In both rat strains and one mouse strain the cataracts occurred after mid - life , were most advanced late in life , and were similar in locations and appearance to those in humans . - pubmed
In the two mouse strains in which some cataracts appeared as early as 10 - 14 months of age , previously identified genetic defects affecting the eye were probably involved in the early appearances . - pubmed
Fulminant liver failure from acute HCV superinfection in a patient with HIV , HBV , and HDV coinfections . - pubmed
Developmental toxicity of 1,6 - hexamethylene diisocyanate ( HDI ) in the Sprague - Dawley rat . - pubmed
Employing multichannel MEG we calculated local Lyapunov exponents ( ILE ) as a measure of the probability of state transitions in patients with mesiotemporal and extra - mesiotemporal focal epilepsy . - pubmed
Altogether , 145 patients with operable invasive breast cancer and clinically negative lymph nodes were studied . - pubmed
The overall accuracy of patients with SNs resected was 98.4 % , and the false - negative rate was 4.4 % . - pubmed
The introduction of magnetic resonance imaging ( MRI ) has greatly improved the evaluation of patients with scoliosis allowing assessment of any underlying intraspinal abnormalities . - pubmed
PURPOSE : To present a case report on a patient with keratouveitis after exposure to a tarantula . - pubmed
CONCLUSION : Hairs from pet tarantulas might penetrate deeply into the eye and give keratouveitis . - pubmed
We describe a child with a disorder that is best described as angiokeratoma of Mibelli . - pubmed
The similarity of both the diffusion coefficients and permeability values obtained for a range of hydrophilic and lipophilic compounds in the two models indicates that the mucus layer secreted by the human adenocarcinoma HT29 - MTX goblet cells does not constitute a diffusion barrier to such compounds . - pubmed
Embryonic ventral mesencephalic grafts to the substantia nigra of MPTP - treated monkeys : feasibility relevant to multiple - target grafting as a therapy for Parkinson ' s disease . - pubmed
We experienced a 30 - year - old man suffering from TCRgammadelta T - cell leukemia with morphology compatible to T - PLL with a postthymic phenotype . - pubmed
We report on a young patient with chronic cervical lymphadenopathy and serological and histological evidence for infection with Bartonella henselae and Toxoplasma gondii . - pubmed
Neuronal ceroid lipofuscinosis in Merino sheep . - pubmed
OBJECTIVE : To characterise neuronal ceroid lipofuscinosis ( NCL ) in Merino sheep . - pubmed
PROCEDURE : NCL cases were studied from a medium - wool Merino flock , the stud of origin of its replacement rams , and an experimental flock established at the University of Sydney . - pubmed
A homozygosity mapping approach localised the gene causing the disease in Merino sheep to the chromosomal region ( OAR7q13 - 15 ) associated with NCL in South Hampshire sheep . - pubmed
CONCLUSION : NCL in Merino sheep is a subunit c - storing disease , clinically and pathologically similar to NCL in South Hampshire sheep . - pubmed
OBJECTIVE : To evaluate the frequency and location and to determine the long - term MR changes in patients with edema - like bone marrow abnormalities after acute knee trauma . - pubmed
DESIGN AND PATIENTS : A cohort of 176 consecutive patients in a 29 month period with acute injury of the knee joint was examined with MRI . - pubmed
Forty - nine patients with bone marrow edema - like signal alteration on the initial MR examination were re - evaluated with MRI after a minimum of 2 years ( mean 44 months ) . - pubmed
Fourteen allelic variants not described in clinical isolates so far were observed among 36 ( 10 % ) of 356 Brazilian strains , including a new pattern for Mycobacterium scrofulaceum , M. - pubmed
METHODS : A 7 - year - old boy with a lateral orbital mass and infratemporal fossa mass underwent computed tomography and surgical excision . - pubmed
Use of serologic tests to predict resistance to feline herpesvirus 1 , feline calicivirus , and feline parvovirus infection in cats . - pubmed
Because most client - owned cats had detectable serum antibodies suggestive of resistance to infection , use of arbitrary booster vaccination intervals is likely to lead to unnecessary vaccination of some cats . - pubmed
OBJECTIVE : Transmyocardial laser revascularization is a new technique that improves symptoms in patients with refractory angina not amenable to conventional revascularization . - pubmed
METHODS : Sixteen patients ( 12 men and 4 women ; mean age , 60 + /- 8 years ) with coronary artery disease were studied . - pubmed
[ Poikllodermia atrophicans vascularis in mycosis fungoldes with indication for treatment with radioactive yttrium ( Y90 ) ] . - pubmed
Cloacal prolapse in ostrich chicks with histomoniosis . - pubmed
Researchers report findings on HIV drug resistance , new infections . - pubmed
In this prospective , randomized , double - blind , controlled study we tested the hypothesis that auricular electroacupuncture ( EA ) relieves pain more effectively than conventional manual auricular acupuncture ( CO ) in chronic low back pain patients with insufficient pain relief ( visual analogue scale [ VAS ] & gt ; or = 5 ) treated with standardized analgesic therapy . - pubmed
Neuropathic pain in particular improved in patients treated with EA . - pubmed
IMPLICATIONS : Continuous electrical stimulation of auricular acupuncture points using the new point stimulation device P - stim significantly decreases pain intensity and improves psychological well - being , activity , and sleep in chronic low back pain patients . - pubmed
Effectiveness of a school - based multicomponent program for the treatment of children with ADHD . - pubmed
Fifty children with ADHD participated in the study . - pubmed
Evaluation of hepatosplanchnic circulation and intestinal oxygenation in dogs with a condition that mimicked septic shock induced by continuous infusion of a low dose of lipopolysaccharide . - pubmed
OBJECTIVE : To determine whether continuous infusion of a low dose of lipopolysaccharide ( LPS ) to induce a condition mimicking septic shock in dogs would affect systemic and hepatosplanchnic circulation and oxygenation . - pubmed
However , in light of the fact that some regenerative capabilities of the endocrine pancreas have been documented and recent research has shown that human ES cell lines can be derived in vitro , this review discusses whether it is practical or even possible to combine these lines of research to more effectively treat young diabetic patients . - pubmed
PURPOSE : We present a 30 - year experience with performing salvage surgery in patients with persistent prostate cancer ( PCA ) after definitive radiotherapy . - pubmed
The charts of all 253 patients seen during a four - month period with a diagnosis of hypertension were analyzed . - pubmed
Here we describe approaches that can be used to study cardiac toxicity in developing zebrafish , focusing on examples where zebrafish embryos have been especially useful in understanding the impact of specific toxicants on heart development and function . - pubmed
The left 48 rats were randomly divided into 4 groups after ovariectomy : group A and B of osteoporotic animal model with normal physiological saline , prevented and treated groups of osteoporotic animal model with BBC . - pubmed
These studies demonstrated , for the first time , the existence of a specialized carrier - mediated system for riboflavin uptake in human - derived retinoblastoma cells . - pubmed
Occupational contact urticaria from walnut associated with hand eczema . - pubmed
PURPOSE : To evaluate tear film quality by rose bengal staining and its stability by breakup time , relating with palpebral fissure height and exophthalmos in patients with Graves ' ophthalmopathy . - pubmed
METHODS : We studied 54 eyes of 27 patients with Graves ' ophthalmopathy , either in the inflammatory or in the chronic phase of the disease . - pubmed
This article describes our experience with laparoscopic procedures for patients with Stage IV colorectal cancer and compares their perioperative outcomes to a contemporaneous group of patients with clinically curable ( Stages I - III ) disease . - pubmed
BACKGROUND : Twenty percent of patients with chronic hepatitis C evolve to cirrhosis in 10 to 20 years . - pubmed
PATIENTS AND METHODS : Retrospective study of 84 liver biopsies of patients with chronic infection with hepatitis C virus were studied . - pubmed
We present the case of a patient with malignant glucagonoma treated with surgery and octreotide , which manifested with skin lesions . - pubmed
Our previous work using the Lewis Lung Carcinoma ( LLC ) model of tumor bearing ( TB )- mice has shown several tumor - induced immune suppressing effects to be present . - pubmed
In this paper , we studied the potential of HS to decrease tumor burden via in vivo treatment of TB - mice . - pubmed
On gross examination , HS treatment produced a decrease in tumor surface necrosis with a visible ( 2 + /- 1.8 % ) surface necrotic area in treated mice as opposed to a ( 43 + /- 16 % ) surface necrotic area in untreated mice . - pubmed
HS treatment decreased TB - mice splenomegaly when comparing mice spleen weights in treated ( 0.3 + /- 0.05 g ) vs. untreated ( 0.14 + /- 0.02 g ) groups . - pubmed
DESIGN : Case series of neonates with severe PPHN ( defined as oxygenation index [ OI ] & gt;20 , failure of iNO therapy , and echocardiographic confirmation of PPHN ) . - pubmed
RESULTS : Nine neonates at a mean gestation of 39.25 + /- 2.76 weeks , birth weight of 3668 + /- 649.1 g , and baseline OI of 28.1 + /- 5.9 received milrinone treatment after a poor initial response to iNO treatment . - pubmed
Infants who received milrinone did not develop systemic hypotension ; in fact , there was a nonsignificant trend toward improved blood pressure . - pubmed
Gender differences in lymphocyte populations , plasma HIV RNA levels , and disease progression in a cohort of children born to women infected with HIV . - pubmed
Background A 75 - year - old woman with rheumatoid arthritis presented with a 4 - year history of chorea to a hospital movement disorder clinic . - pubmed
Aseptic peritonitis in a peritoneal dialysis patient . - pubmed
INTRODUCTION : Patients who have repeatedly sterile peritoneal fluid cultures despite elevated peritoneal fluid white cell count should be evaluated for disorders other than usual bacterial peritonitis . - pubmed
CASE REPORT : A 25 - year - old male non - diabetic patient in PD started his complains with diffuse abdominal pain with spontaneous remissions and exacerbations , anorexia and vomiting with 3 days evolution . - pubmed
Y chromosome deletions arise frequently in human populations , where they cause sex reversal and Turner syndrome and predispose individuals to infertility and germ cell cancer . - pubmed
Subjects were 34 patients , 32 men and 2 women , with squamous cell carcinoma of the oropharynx , with a median age of 63 years ( range , 47 to 72 year ) . - pubmed
Samples comprised 8 diploid species of Coffea , 5 individuals of tetraploid C. - pubmed
METHODS : This was a nonrandomized observational prospective trial over 9 months , with data collection on 28 eyes of 26 consecutive patients who underwent phacovitrectomy , internal limiting membrane peel , and intraocular gas tamponade ( C2F6 ) for stage 2 , 3 , and 4 macular holes . - pubmed
The combination of phacoemulsification , pars plana vitrectomy , internal limiting membrane , and gas tamponade in macular hole surgery reduces the difficulty of posturing in elderly patients . - pubmed
This technique saves the patient from exposure to a second intraocular intervention to remove a cataract which will commonly develop after vitrectomy and gas tamponade alone . - pubmed
Like the mammalian nervous system , the Lymnaea nervous system responds to injury with recruitment and activation of endoneurial phagocytes ( i.e. - pubmed
PURPOSE : To evaluate the effect of the size of zona pellucida opening by laser assisted hatching for frozen cleaved embryo that were thawed after both fresh and frozen cleaved embryo transfer cycles failed and were cultured to blastocyst after thawing in patients with multiple implantation failures . - pubmed
MATERIALS AND METHODS : Of 101 consecutive procedures ( October 2003 to June 2006 ) , 30 patients declined to perform assisted hatching and were selected as control group , 40 patients had 40 microm opening of the zona ( October 2003 to January 2005 ) , 31 patients had 50 % of the zona opening ( February 2005 to June 2006 ) . - pubmed
Three patients experienced a full - thickness epithelial breakthrough and the fourth , a flap tear . - pubmed
The patient who experienced the flap tear was unable to have laser in situ keratomileusis successfully . - pubmed
The flap complications did not result in a decreased best corrected visual acuity in any patient but may have resulted in epithelial ingrowth in one and a corneal scar and microstriae in another . - pubmed
CONCLUSIONS : The results indicate that sounds from pulse oximeters pose a potential risk of not only sleep disturbance and annoyance but also hearing loss , and that these sounds are unnatural for human auditory perception . - pubmed
Using integrative genomics to elucidate genetic resistance to Marek ' s disease in chickens . - pubmed
This briefly summarizes some of our efforts to apply several genomic and functional genomics approaches to identify genes and pathways that confer genetic resistance to Marek ' s disease ( MD ) , a herpesvirus - induced T cell lymphoma of chickens . - pubmed
By utilizing the " top - down " approach of QTL to identify genomics regions , and integrating it with " bottom - up " approaches of transcript profiling and Marek ' s disease virus ( MDV)-chicken protein - protein interactions , three genes that confer resistance to MD are revealed , plus a number of other positional candidate genes of high confidence . - pubmed
Of 12 infants ( 3 boys and 9 girls ) , 9 have a family history of DM . - pubmed
Studies on hypertension ; mechanism of the fall in arterial pressure produced by high spinal anesthesia in patients with essential hypertension . - pubmed
Further determination of recurrence and progression marker will contribute to establish better treatments for the individual patient . - pubmed
OBJECTIVE : Cytomegalovirus ( CMV ) is an important pathogen in healthy neonates and individuals with human immunodeficiency virus ( HIV-1 ) . - pubmed
The objective of this study was to determine whether the detection of CMV DNA ( CMV DNAemia ) in maternal plasma was associated with mortality in HIV-1 - infected women or their infants . - pubmed
Additionally , HIV-1 - infected infants born to CMV DNAemic women had a four - fold increased risk of mortality during 24 months of follow - up . - pubmed
CONCLUSION : Maternal plasma CMV DNAemia identified a subgroup of Kenyan women and infants at high risk for death in the 2 years following delivery . - pubmed
Anatomical architecture and responses to acidosis of a novel respiratory neuron group in the high cervical spinal cord ( HCRG ) of the neonatal rat . - pubmed
Neuroprotective effects of probenecid in a transgenic animal model of Huntington ' s disease . - pubmed
In this study , we examined the effects of probenecid on the survival , behaviour and immunohistochemical changes in the N171 - 82Q transgenic mouse model of HD . - pubmed
However , the time resolution in STEMI patients is hampered by the rather vague time point ' onset of pain ' . - pubmed
We therefore sought to utilize a time - wise more reliable model of human myocardial necrosis : percutaneous transluminal septal myocardial ablation ( PTSMA ) of hypertrophic obstructive cardiomyopathy ( HOCM ) . - pubmed
METHODS : Blood samples were obtained from 8 patients with HOCM just prior to initiation of PTSMA and up to 50 h following the procedure . - pubmed
BACKGROUND : The rationale for screening populations at risk for hepatitis C virus infection ( HCV ) includes the possibility of altering risk behaviors that impact disease progression and transmission . - pubmed
they were documented HCV seronegative at study onset and subsequently seroconverted during the follow - up period , with infection confirmed by HCV RNA testing . - pubmed
PATIENT REPORT : A 68 - year - old man with invasive bladder cancer disseminated in penile shaft and the pelvic lymph nodes is presented . - pubmed
Inadequate antigen presentation and/or suboptimal immunogenicity are considered major causes in the failure of human immunodeficiency vaccine to adequately protect against wild - type virus . - pubmed
Cardiovascular changes in spontaneously hypertensive rats are improved by chronic treatment with zofenopril . - pubmed
BACKGROUND AND PURPOSE : The aim of this study was to investigate the effect of chronic treatment with antihypertensive and non - antihypertensive doses of zofenopril on cardiovascular changes in spontaneously hypertensive rats ( SHR ) . - pubmed
OBJECTIVE : To analyze the results of pre - operative local therapy for hepatocellular carcinoma in patients who were subjected to liver transplantation . - pubmed
METHODS : Cadaveric and living - related liver transplants done in cirrotic patients with hepatocellular carcinoma within the Milan criteria were included . - pubmed
CONCLUSION : Local therapy for hepatocellular carcinoma with percutaneous ethanol injection and transarterial chemoembolization partially controlled tumor evolution considering the Milan criteria in patients waiting for liver transplantation . - pubmed
Susceptibility of carbapenemase - producing strains of Klebsiella pneumoniae and Escherichia coli to the direct antibacterial activity of NAB739 and to the synergistic activity of NAB7061 with rifampicin and clarithromycin . - pubmed
OBJECTIVES : To determine the susceptibility of carbapenemase - producing strains of Klebsiella pneumoniae and Escherichia coli to the direct antibacterial activity of NAB739 and to the synergistic activity of NAB7061 with rifampicin and clarithromycin . - pubmed
RESULTS : The MICs of NAB739 for all nine polymyxin - susceptible , carbapenemase - producing strains were identical or very close to those determined for E. - pubmed
The polymyxin - resistant strain K. - pubmed
In addition , NAB7061 has notable synergism with rifampicin and clarithromycin against all the carbapenemase - producing strains tested , including the polymyxin - resistant K. - pubmed
For allogeneic stem cell transplant , the conditioning chemotherapy regimen comprised busulfan , cyclophosphamide , and antithymocyte globulin for thalassemic patients ; busulfan and cyclophosphamide for leukemia patients ; and cyclophosphamide and antithymocyte globulin for patients with aplastic anemia . - pubmed
RESULTS : During this period , 155 B - thalassemia major patients ( mean age , 9.5 years ; range , 2 - 20 years ) underwent allogeneic marrow transplant . - pubmed
Of 155 patients with a diagnosis of thalassemia major , 112 are alive ( 72 % ) with full engraftment after a median follow - up of about 8.1 years ( range , 12 - 184 months ) . - pubmed
During this time , 127 leukemia patients including acute myelogenous leukemia ( n=68 ) , acute lymphoblastic leukemia ( n=30 ) and chronic myelogenous leukemia ( n=29 ) , received allogeneic stem cell transplant . - pubmed
In patients with B - thalassemia major hematopoietic stem cell transplant seems to be the treatment of choice , because it leads to a cure in all classes ( Lucarelli risk group , I - III ) . - pubmed
Murine spleen lymphocytes apoptosis in the experimental model of staphylococcal intravaginal infection . - pubmed
The results of research on changes in the level of apoptosis among the spleen cells during the development of intravaginal staphylococcal infection in experimental models of different genetic mice lines are given in the paper . - pubmed
Chronic osteomyelitis complicating war compound fractures ; an evaluation of 125 patients treated by early secondary closure . - pubmed
Epileptogenic glioma in a 4 - year - old child : a case report . - pubmed
This 4 - year - old girl presented with a 1 - year history of complex partial seizure . - pubmed
This is apparent in depressive patients with BPD . - pubmed
It also improves sleep - wake patterns and behavioural disorders in hospitalized patients with Alzheimer ' s disease . - pubmed
The treatment of comorbid depressive disorder and borderline personality disorder ( BPD ) is usually reported to be less successful than the treatment of patients without personality disorder . - pubmed
RESULTS : Five patients discontinued from the trial due to oral administration of Iressa after disease progression or other reasons , and 116 patients were evaluable for clinical efficacy with 63 in the treatment group and 53 in the control group . - pubmed
CONCLUSIONS : Chinese herbal medicine combined with chemotherapy showed favorable effect in improving quality of life and prolonging survival time on patients with advanced NSCLC . - pubmed
The data acquired in this pilot study validate BoHV-4 - based vector as a safe and effective heterologous antigen carrier / producer for the formulation of enhanced recombinant immunogens for the vaccination against lethal bluetongue . - pubmed
We report a case of a patient with chronic kidney disease likely due to lead nephropathy . - pubmed
Retrospective study on the effect of tight glucose control in postoperative sepsis patients using an artificial pancreas . - pubmed
The present study was undertaken to examine whether the use of an artificial pancreas to achieve TGC would be possible in postoperative patients with sepsis . - pubmed
No hypoglycemia associated with the artificial pancreas was seen in any of the patients . - pubmed
Further data collection from a larger number of cases would be expected to allow a precise assessment of TGC as a potentially beneficial intervention in sepsis patients . - pubmed
Avotermin for scar improvement following scar revision surgery : a randomized , double - blind , within - patient , placebo - controlled , phase II clinical trial . - pubmed
METHODS : Sixty patients ( 35 men and 25 women ; age , 19 to 78 years ; 53 Caucasians ; scar length , 5 to 21 cm ) received intradermal avotermin ( 200 ng/100 mul / linear cm wound margin ) and placebo to outer wound segments immediately after , and again 24 hours after , complete ( group 1 ) or staged ( group 2 ) scar revision surgery . - pubmed
A within - patient design was chosen to control for interindividual factors that affect scarring . - pubmed
This method could be useful for quantitative gene expression analysis in blood vessels from tumors of patients that have been treated with antiangiogenic drugs , allowing for validation of the effect of drug on the expected targets . - pubmed
Serum levels of 25 - hydroxyvitamin D and survival in Norwegian patients with cancer of breast , colon , lung , and lymphoma : a population - based study . - pubmed
METHODS : The study population was 658 patients with cancers of the breast ( n = 251 ) , colon ( n = 52 ) , lung ( n = 210 ) , and lymphoma ( n = 145 ) , obtained from JANUS , a population - based serum bank in Norway . - pubmed
A total of 149 patients with multiple myeloma ( MM ) who received allogeneic hematopoietic stem cell transplantation ( allo - HCT ) with myeloablative ( MAC ; n = 38 ) or reduced - intensity conditioning ( RIC ; n = 110 ) regimens at MD Anderson Cancer Center were evaluated . - pubmed
Median age of MM patients was 50 ( 28 - 70 ) years with a followup time of 28.5 ( 3 - 164 ) months . - pubmed
We observe that TRM has decreased with the use of RIC regimens , and long - term disease control can be expected in a subset of MM patients undergoing allo - HCT . - pubmed
AIMS : To determine ( 1 ) the accuracy of positron emission tomography - computed tomography in the diagnosis of head and neck cancer , ( 2 ) the learning curve involved , and ( 3 ) whether its use alters patient management . - pubmed
MATERIALS AND METHODS : A retrospective study including 80 patients with head and neck cancer who underwent positron emission tomography - computed tomography image fusion at Blackpool Victoria Hospital . - pubmed
RESULTS : Fifty - three patients underwent positron emission tomography - computed tomography for staging ( 32 for detection of a primary tumour and 21 for detection of distant metastasis ) and 27 for detection of loco - regional recurrence . - pubmed
Eighteen patients had their tumour stage and management modified as a result of this method of imaging . - pubmed
METHODS : In this retrospective cross sectional study , 426 patients with cholecystitis who were admitted to Hamadan hospitals including Ekbatan , Tamin Ejtamaiee , Mobasher , Boali and Artesh and were subjected to laparoscopic cholecystectomy from 1997 to 2005 were evaluated . - pubmed
We included individuals with unilateral vestibular nerve schwannomas confirmed by imaging . - pubmed
RESULTS : A total of 44 patients with vestibular nerve schwannomas and 104 controls participated in the study . - pubmed
In the JT - group , relaparotomy was performed in three patients ( 6 % ) because of JT - leakage or strangulation leading to death in one patient ( 2 % ) . - pubmed
Protective effect of omega-3 polyunsaturated fatty acids ( PUFAs ) on sodium nitroprusside - induced nephrotoxicity and oxidative damage in rat kidney . - pubmed
The results of the present study suggest that omega-3 PUFA - enriched FO and FXO from seafoods and plant sources , respectively , are similarly effective in reducing SNP - induced nephrotoxicity and oxidative damage . - pubmed
We examined frozen samples from the cerebellum and temporal cortex ( Brodmann area 22 ( BA22 ) ) from individuals with autism and unaffected controls ( n=15 and n=12 per group , respectively ) . - pubmed
Batrachochytrium dendrobatidis ( Bd ) is the causative agent of chytridiomycosis , a fungal skin disease in amphibians and driver of worldwide amphibian declines . - pubmed
Ninety neuropathic diabetic foot patients were divided into two groups : group B [ those without CAD ( n=45 ) ] and group C [ those with higher risk of CAD ( n=45 ) ] . - pubmed
We reveal that exposure - based perceptual learning is more efficient in a human model of excitotoxic neurodegeneration than in healthy participants . - pubmed
Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development . - pubmed
These findings imply that Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development . - pubmed
Two entry inhibitors are currently approved for the treatment of HIV - infected patients . - pubmed
This review covers the entry inhibitors and their use in the treatment of HIV - infected patients . - pubmed
More than half of the patients with high - risk neuroblastoma ( NB ) will relapse despite intensive multimodal therapy , with an additional 10 % to 20 % refractory to induction chemotherapy . - pubmed
Management of these patients is challenging , given disease heterogeneity , resistance , and organ toxicity including poor hematological reserve . - pubmed
Immunotherapy with anti - GD2 has recently been incorporated into upfront therapy , but its role in the relapse setting remains uncertain , especially for patients with bulky disease . - pubmed
Prevalence of hemostatic disorders in adolescents with abnormal uterine bleeding . - pubmed
STUDY OBJECTIVE : To evaluate the incidence of hemostatic disorders in a population of adolescents with various patterns of abnormal uterine bleeding ( AUB ) . - pubmed
PARTICIPANTS : One hundred thirteen adolescents with AUB ; mean age at menarche and mean age at the onset of symptoms 12 + - 1.2 years and 13.5 + - 2.8 years , respectively . - pubmed
All patients were screened for hemostatic disorders with laboratory testing . - pubmed
RESULTS : One hundred thirteen adolescents with AUB were identified . - pubmed
CONCLUSION : AUB in adolescents is frequently associated with an underlying disorder of hemostasis , most commonly a platelet function disorder . - pubmed
The results highlight the importance of screening for coagulation disorders in adolescents with AUB , independently from the gynecologic age at onset . - pubmed
MATERIALS AND METHODS : Fifty - three consecutive gastric adenocarcinoma patients who underwent gastric resection ( Chung - Ang University Hospital , Seoul , Korea ) were included . - pubmed
Cytotoxicity and gene expression profiling of polyhexamethylene guanidine hydrochloride in human alveolar A549 cells . - pubmed
In Korea , lung disease of children and pregnant women associated with humidifier disinfectant use has become a major concern . - pubmed
This study was done to elucidate the putative cytotoxic effect of PHMG and the PHMG - mediated altered gene expression in human alveolar epithelial A549 cells in vitro . - pubmed
METHODS : The authors retrospectively reviewed the medical records of 47 consecutive patients with CSA in whom the presence / absence of the pyramidal tract sign was noted . - pubmed
Although this species is increasingly relevant to public health due its ability to successfully colonize both urban and rural habitats , favoring the dispersion of viral infections , little is known about its biochemical traits , with all assumptions made based on studies of A. - pubmed
THIS LITERATURE REVIEW HAS THE FOLLOWING OBJECTIVES : to define selection criteria for patients who are candidates for focal therapy , to assess the current situation and results of the different therapeutic options , and to define procedures in cases of recurrence and for follow - ups . - pubmed
INTRODUCTION : Specialised care of patients in advanced stages of chronic kidney disease ( CKD ) is associated with better survival in dialysis , but it is not known which treatments specifically favour this outcome . - pubmed
MATERIAL AND METHOD : Cohort , prospective observational study of 591 patients who started dialysis ( 491 haemodialysis and 100 peritoneal dialysis ) , who had previously been monitored in the CKD clinic . - pubmed
Single - institution Experience of SBRT for Lung Metastases in Sarcoma Patients . - pubmed
OBJECTIVES : Lung metastasectomy is regarded as the standard procedure for improving the prognosis of patients with metastatic sarcoma . - pubmed
MATERIALS AND METHODS : Twenty - two patients with metastatic sarcoma to lung were treated by SBRT . - pubmed
CONCLUSION : SBRT is an effective tool that might be used as an alternative to operative treatment of lung metastases in sarcoma patients . - pubmed
Host immunity to Clostridium difficile PCR ribotype 017 strains . - pubmed
Clostridium difficile is an important nosocomial pathogen and the leading cause of antibiotic - associated diarrhea . - pubmed
METHODS : This prospective physiological study was performed in a university hospital 's paediatric intensive care unit and included 11 children ( aged 35.2 + - 23 days ) with respiratory syncytial virus bronchiolitis with failure of nCPAP . - pubmed
METHODS : This double - blind , placebo - controlled , randomized clinical trial included 85 participants with clinically definite MS , 45 assigned to the treatment group and 40 to the placebo - control group . - pubmed
All patients had Fuchs ' endothelial dystrophy and had previously received hydrophilic acrylic IOL models . - pubmed
A man in his 50s was admitted to our hospital for treatment of hematemesis . - pubmed
RESULTS : We documented 780 admitted patients , mean age 70.43 years , 31 % with heart disease , 29 % COPD , 26 % diabetes mellitus , 15 % prior antibiotic therapy and solid neoplasm . - pubmed
METHODS : For this study we retrospectively reviewed data from 193 patients who experienced drug hypersensitivity reactions during general anaesthesia . - pubmed
Seven PCA patients , 6 TAD patients and 5 controls underwent neuropsychological assessment , MRI scan , 11C - PIB PET scan and 18F - FDG PET scan . - pubmed
And PCA patients showed more severe posterior atrophy and less severe left medial temporal lobe atrophy compared with TAD patients . - pubmed
Our study thus provides a preliminary view of PCA in Chinese patients . - pubmed
, rotavirus , porcine transmissible gastroenteritis virus , and porcine epidemic diarrhea virus . - pubmed
PRESENTATION OF CASE : We report a 4.5 year old female patient who had upper airway obstruction due to a fragmented and migrated tracheostomy tube . - pubmed
The effects of an Ayurvedic medicinal toothpaste on clinical , microbiological and oral hygiene parameters in patients with chronic gingivitis : a double - blind , randomised , placebo - controlled , parallel allocation clinical trial . - pubmed
OBJECTIVES : To study the efficacy of an Ayurvedic toothpaste containing these herbs in patients with chronic gingivitis . - pubmed
CONCLUSIONS : This study provides robust evidence of the beneficial antiplaque and antigingivitis effects of the test herbal toothpaste Sudantha on patients with chronic gingivitis . - pubmed
PURPOSE OF REVIEW : An increasing number of patients are placed on extracorporeal membrane oxygenation ( ECMO ) for respiratory or cardiac failure . - pubmed
PURPOSE : About one - third of individuals with focal epilepsy continue to have seizures despite optimal medical management . - pubmed
Animals that received these perineural local anesthetics ( LAs ) injections showed increased severity of injury compared to the control group . - pubmed
Etiology search included testing for hepatitis B virus ( HBV ) , hepatitis C virus ( HCV ) , autoimmune hepatitis , primary biliary cirrhosis , Wilson ' s disease and hereditary hemocromatosis . - pubmed
BACKGROUND : Parkinson ' s disease ( PD ) is a progressive neurodegenerative disorder of the central nervous system , observed in patients aged older than 50 years . - pubmed
Moreover , in view of the lack of evidence - based recommendations regarding the pharmacotherapy of arterial hypertension in PD patients , we propose effective and safe therapeutic algorithms for these two coexisting conditions . - pubmed
Three hundred preterm neonates with hemodynamically significant PDA ( hs - PDA ) admitted at our neonatal intensive care unit were enrolled in the study . - pubmed
CONCLUSION : Paracetamol is as effective as indomethacin and ibuprofen in closure of PDA in preterm neonates and has less side effects mainly on renal function , platelet count , and GIT bleeding . - pubmed
Anaphylaxis to hidden potato allergens in a peach and egg allergic boy . - pubmed
Sweets are frequently implicated in allergic reactions in children with cow 's milk , egg , nuts or fruits allergy , and they are the most relevant foods investigated as responsible allergens . - pubmed
We report an anaphylactic reaction to candies in an egg and peach allergic boy . - pubmed
RESULTS : Uterine papillary serous carcinoma : 5432 women with UPSC were identified . - pubmed
Uterine clear cell carcinoma : 2516 women with UCC were identified . - pubmed
Postural Control in Children with Dyslexia : Effects of Emotional Stimuli in a Dual - Task Environment . - pubmed
Twenty - two children with dyslexia and twenty - two aged - matched children without dyslexia participated in the study . - pubmed
CASE DESCRIPTION : We report a lumbar 3 - 4 lesion causing cauda equina compression in a 57 - year - old man who presented with a 3 - month history of low back pain and bilateral sciatica , intermittent urinary incontinence , and erectile dysfunction . - pubmed
The study includes seventeen PD patients and sixteen age - matched controls . - pubmed
Population pharmacokinetics of lamotrigine co - administered with valproic acid in Chinese epileptic children using nonlinear mixed effects modeling . - pubmed
METHODS : A total of 182 epileptic children who were treated with LTG as monotherapy or as part of combination therapy were included in this study as the model group , and 61 patients were included as the validation group . - pubmed
Background Kyphoplasty has been demonstrated to be minimally invasive and effective in treating osteoporotic vertebral fracture patients with back pain over the level of the fractured vertebrae . - pubmed
Rare studies have reported on thoracolumbar vertebral fracture patients presenting with distal lumbosacral pain ( DLP ) . - pubmed
Purpose To evaluate the therapeutic efficacy of kyphoplasty in treating osteoporotic thoracolumbar vertebral fracture ( OTVF ) patients with DLP and assess the clinical significance of focal tenderness to palpation in these patients . - pubmed
Material and Methods Thirty - two OTVF patients who only complained of DLP were treated by kyphoplasty . - pubmed
In addition , we compared the therapeutic efficacy of kyphoplasty in patients with and without focal tenderness to palpation . - pubmed
Conclusion The possibility of thoracolumbar vertebral fractures in elderly patients complaining of DLP should not be neglected . - pubmed
Kyphoplasty presents a superior benefit in treating OTVF patients with DLP . - pubmed
The absence of focal tenderness does not influence the clinical efficacy in these patients . - pubmed
Children aged 2 to 18 years old who presented with acute abdominal pain suggesting appendicitis were included . - pubmed
Amrubicin monotherapy for elderly patients with relapsed extensive - disease small - cell lung cancer : A retrospective study . - pubmed
However , the efficacy of AMR in elderly patients with relapsed SCLC has not been sufficiently evaluated . - pubmed
METHODS : The medical records of elderly patients with relapsed SCLC who received AMR as second - line chemotherapy were retrospectively reviewed , and their treatment outcomes were evaluated . - pubmed
RESULTS : Thirty - one patients with a median age of 72 years ( 22 patients with sensitive relapse and 9 with refractory relapse ) were analyzed . - pubmed
The PFS ( 6.2 vs. 3.2 months ; P = 0.002 ) and OS ( 14.8 vs. 5.7 months ; P = 0.004 ) were significantly longer in patients with sensitive relapse than those with refractory relapse . - pubmed
The frequency of grade 3 or higher neutropenia was high ( n = 18 , 58 % ) , while febrile neutropenia was only observed in five patients ( 16 % ) . - pubmed
CONCLUSION : AMR may be a feasible and effective regimen for elderly patients with relapsed SCLC . - pubmed
RESULTS : We identified 75,666 patients treated for urethral stricture disease , with 420 and 367 undergoing anterior and posterior urethroplasty , respectively . - pubmed
This study suggests that the hsa_circ_0044235 in peripheral blood may be a potential biomarker of patients with RA . - pubmed
Antiemetic use of olanzapine in patients with advanced cancer : results from an open - label multicenter study . - pubmed
The drug has a mean half - life of 30 h , which allows for a single daily administration and is therefore of interest in patients with advanced cancer suffering from nausea . - pubmed
OBJECTIVES : To investigate the antiemetic effect and tolerability of olanzapine in patients with advanced cancer not receiving chemotherapy or irradiation . - pubmed
METHODS : Patients with advanced cancer ( no curable treatment options ) with at least " moderate " nausea and/or one emetic episode within the last 24 h were included if they had not received chemotherapy or irradiation ( last 2 weeks ) and had no reversible causes of nausea / vomiting . - pubmed
The primary efficacy parameter was nausea after 24 h. RESULTS : Forty patients from four centers were included and all evaluable after 24 h. Thirty - six patients experienced some degree of improvement . - pubmed
Five patients were withdrawn from the study primarily due to progression of malignant disease or per patient 's request . - pubmed
CONCLUSIONS : Olanzapine appears effective and tolerable as an antiemetic in patients with advanced cancer . - pubmed
Of the 1049 patients who received stereotactic radiation therapy for brain metastases , only 2 % had adjuvant whole brain radiation therapy , and this decreased from 4 % in 2013 to 0.7 % in 2017 ( P = .02 ) . - pubmed
Emerging evidences indicate that hepatitis B virus ( HBV ) infection is associated with non - Hodgkin lymphoma ( NHL ) , but the mechanisms of HBV - induction lymphomagenesis remain unclear . - pubmed
Increased risk of head injury in pediatric patients with attention deficit hyperactivity disorder . - pubmed
In the writhing test , both hybrids showed significant an antinociceptive effect in mice , while neither of them triggered the development of tolerance , nor did they produce constipation . - pubmed
Background : This study aims to evaluate the outcomes of sublobar resections in patients with early - stage non - small cell lung cancer and to investigate the factors affecting survival . - pubmed
Methods : Medical files of a total of 63 patients ( 52 males , 11 females ; mean age 64 years ; range , 39 to 81 years ) who underwent sublobar resection for suspected or known early - stage non - small cell lung cancer between January 2001 and August 2013 were retrospectively reviewed . - pubmed
Data including demographic characteristics of the patients , comorbid conditions , smoking status , surgical margin , visceral pleura invasion , distance from surgical margin to tumor , tumor size , pathological N status , cell type , tumor localization , and recurrences were recorded . - pubmed
Effects of Antipsychotic Medication on Brain Structure in Patients With Major Depressive Disorder and Psychotic Features : Neuroimaging Findings in the Context of a Randomized Placebo - Controlled Clinical Trial . - pubmed
Importance : Prescriptions for antipsychotic medications continue to increase across many brain disorders , including off - label use in children and elderly individuals . - pubmed
All participants had major depressive disorder with psychotic features ( psychotic depression ) and were prescribed olanzapine and sertraline for a period of 12 to 20 weeks , which included 8 weeks of remission of psychosis and remission / near remission of depression . - pubmed
BACKGROUND : In Canada , although the incidence of smoking - related oral cavity cancers has decreased , oropharyngeal cancers associated with human papilloma virus ( HPV ) are on the rise . - pubmed
Hematopoietic stem cells are used in transplantations for patients with hematologic malignancies . - pubmed
Assessment of Thymic Output Dynamics After in utero Infection of Mice With Coxsackievirus B4 . - pubmed
We recently documented coxsackievirus B4 ( CV - B4 ) infection of Swiss albino mouse thymus in the course of in utero transmission . - pubmed
Derivation and validation of a clinical prediction model for assessing the risk of lower extremity amputation in patients with type 2 diabetes . - pubmed
RESULTS : A total of 504 patients developed LEA at an average follow - up of 7.4 years . - pubmed
Poor glycemic control , glucose variation , comorbidities , and medication use were identified as predictive factors for LEA in patients with type 2 diabetes . - pubmed
Since the outbreak of coronavirus disease ( COVID-19 ) that was discovered in 2019 in Wuhan , China , no standard therapy guideline has been set despite the severity of severe acute respiratory syndrome coronavirus 2 ( SARS - CoV-2 ) and its high infectivity . - pubmed
The Cellular basis of the loss of smell in 2019 - nCoV - infected individuals . - pubmed
The identity of the cell lineages that underpin the infection - associated loss of olfaction could be critical for the clinical management of 2019 - nCoV - infected individuals . - pubmed
We studied if anosmia in 2019 - nCoV - infected individuals can be explained by the expression patterns associated with these host - specific moieties across the known olfactory epithelial cell types , identified from a recently published single - cell expression study . - pubmed
We used WGS data to investigate the genetic diversity of clinical isolates of the bacterial pathogen Elizabethkingia anophelis to query the existence of a single - strain outbreak in Ontario , Canada . - pubmed
From the roots to the stem : unveiling pear root colonization and infection pathways by Erwinia amylovora . - pubmed
Plant infections after soil irrigation with E. - pubmed
Overall , our findings revealed , for the first time , common root infection patterns between E. - pubmed
Causes of readmission include pseudomeningocele ( 8 patients ; 38 % ) , CSF leakage combined with poor incision healing ( 6 patients ; 29 % ) , wound dehiscence ( 2 patient ; 9 % ) , surgical site infection ( 2 patients ; 9 % ) , spinal epidural hematoma ( 1 patient ; 5 % ) , inadequate original surgical decompression ( 2 patients ; 9 % ) . - pubmed
When compared to the non - readmitted patients , diagnosis of OPLL + OFL , circumferential decompression , dural injury , long hospital stay were more to be seen in readmitted patients . - pubmed
Four cases , given in some detail , illustrate the effort to compare scalp EEGs taken before surgery for intractable seizures with those recorded some years postoperatively , and to relate these , together with the computer analyses of seizure activity recorded in depth , with the pathology found in the removed tissue and , importantly , with the postoperative clinical state of the patient . - pubmed
Inorganic phosphate inhibited the biosynthesis of the macrolide antibiotic turimycin in different strains of Streptomyces hygroscopicus . - pubmed
The test was done in 10 horses and 15 ponies with naturally acquired parasitic infections . - pubmed
Ultrastructural studies were performed on portions of the operatively resected right atrium from six patients with a ventricular septal defect and six patients with an endocardial cushion defect . - pubmed
The six patients with a ventricular septal defect had normal right atrial mean pressure and no evidence of right atrial volume overload . - pubmed
The six patients with an endocardial cushion defect had elevated right atrial mean pressure and evidence of right atrial volume overload . - pubmed
No adverse effects were observed in the dogs and rats other than alopecia in rats at the dose levels of 5.0 and 11.8 ppm . - pubmed
Renal failure developed in 20 patients following blunt civilian trauma . - pubmed
[ Effect of obsidan on the course of experimental myocardial infarct with arrhythmias in rabbits ] . - pubmed
Experimental myocardial infarction ( EMI ) was reproduced in 35 of 40 rabbits operated upon . - pubmed
Reintroduction of obsidan to rabbits with EMI complicated by sinus bradycardia and ventricular extrasystole is prognostically dangerous ( ventricular extrasystole relapses and its transformation into ventricular tachycardia is possible ) . - pubmed
Two patients are described who presented with clinically solitary thyroid nodules which were found to be due to metastatic disease from the kidney and colon respectively . - pubmed
Human red cell and plasma lipids are determined in alcoholic patients with various forms of liver diseases including steatosis , cirrhosis and hepatitis . - pubmed
The incidence of hyperparathyroidism was not influenced by the age of the patient , but it increased with duration of dialysis . - pubmed
Of 16 patients treated by subtotal parathyroidectomy , all had large hyperplastic parathyroid glands . - pubmed
All of the patients who were observed for longer than six months had progressive improvement in the bone disease . - pubmed
Hyperparathyroidism is a significant problem in the dialysis patient , despite phosphate control . - pubmed
[ Occupational allergy due to inhalation of pollen from Euphorbia fulgens Karw ( author 's transl ) ] . - pubmed
The author reviews the structure of nephropathies on the basis of an analysis of the clinicomorphological data obtained during the follow - up of 3000 patients examined at the nephrological center . - pubmed
Many patients with EMS exhibited clinical and histopathological features similar to another epidemic , the toxic oil syndrome ( TOS ) , associated with ingestion of adulterated rapeseed oil . - pubmed
Patients with TOS or EMS had significantly higher L - kynurenine and quinolinic acid than healthy control subjects or rheumatic disease control subjects . - pubmed
Neopterin was also elevated in patients with untreated TOS and EMS , and correlated strongly with L - kynurenine and quinolinic acid . - pubmed
Genetic contributions to T - cell recognition in murine lupuslike autoimmune disease . - pubmed
Simultaneous , blood pressure became unmeasurable , and the patient became cyanosed . - pubmed
It was concluded that , in our area , Streptococcus pyogenes still has an excellent sensitivity to penicillin G and to other antibiotics which may be a therapeutic alternative in allergic patients or an empiric treatment in infections likely to be produced , among other organisms , by S. - pubmed
In patients with established lung disease this is due to a combination of proteolytic degradation , complex with enzyme and oxidation at the active site . - pubmed
Lymph node biopsies from 43 male homosexuals with persistent generalized lymphadenopathy and from ten acquired immunodeficiency syndrome patients , all with serum antibodies to human T - cell leukemia virus III , were studied with regard to histopathology , immunohistology , and T - cell subsets in cell suspensions . - pubmed
Our observations indicate the occurrence of marked changes not only in T - cells but also in the B - cell compartment of patients with persistent generalized lymphadenopathy or acquired immunodeficiency syndrome . - pubmed
Seventy - five percent of patients experienced relief of symptoms referable to their ascites . - pubmed
Significant alterations in coagulation parameters consistent with subclinical disseminated intervascular coagulation ( DIC ) were present in all patients with functioning shunts . - pubmed
The best results can be expected in those patients with ovarian and breast primary tumors . - pubmed
Results of clinico - functional examination in workers engaged in production of monomethylaniline semifinished products revealed a more frequent morbidity of the internal organs , moderate methemoglobinemia , functional changes of the cardio - vascular system , disorders of the pulmonary ventilation function , metabolic processes . - pubmed
Administration of oestradiol to three strains of female mice induced the oestrous phase of the reproductive cycle in which there are few or no polymorphonuclear leucocytes ( PMNL ) in vaginal smears . - pubmed
BALB / c mice were the most susceptible , all of 10 becoming colonised ; two other strains were less susceptible and untreated mice were resistant . - pubmed
The numbers of ureaplasmas recovered from the vagina ranged from 10(2 ) to 10(7 ) colour - changing units ( ccu)/ml , irrespective of the strain of mice , and in some there was spread to the uterine horns and ovaries , and to the spleen in one mouse . - pubmed
Intraperitoneal ( ip ) injection of cholecystokinin octapeptide sulfate ester ( CCK ; 5 , 10 and 50 micrograms / kg ) reduced the hypothermic response to 8 mg / kg and 32 mg / kg systemic morphine in restrained and freely moving rats , respectively . - pubmed
The DNA substrates used in binding experiments were two fragments from Drosophila heat shock locus 87A7 . - pubmed
Nearly half of the patients in the epidural experienced slight peroperative pain . - pubmed
DDAVP ( FPA was only measured before DDAVP ) in 20 patients with diabetes mellitus . - pubmed
Though clinically normal , A - T heterozygotes share a high risk of cancer with A - T homozygotes and constitute approximately 1 % of the human population . - pubmed
Am J Pathol 64:483 - 500 , 1971 ) liver biopsies of renal transplant patients who developed chronic progressive viral hepatitis associated with persistence of Australia antigenemia [ Au(1 ) ] while under immunosuppressive therapy were studied . - pubmed
To investigate the relationship of these virus - like particles to Australia antigen , 2 of the Au ( 1 ) hepatitis renal transplant patients were restudied 6 to 8 months later . - pubmed
[ Morphology and histochemistry of the jejunal mucosa in patients with lactase deficiency ] . - pubmed
[ The syndrome induced in the rat with dextrans is not anaphylactic ] . - pubmed
In order to achieve a more realistic view of the ultrastructural events during HSV infection of adult tissue , cell cultures were prepared from adult mouse and rat livers and infected with several HSV strains . - pubmed
Dedifferentiated variants of a rat hepatoma : reversion analysis . - pubmed
A rapid liquid chromatographic method for monitoring the 6 neutral amino acid levels in serum , valine , leucine , isoleucine , tyrosine , phenylalanine and methionine , has been developed for use as one of the routine clinical laboratory tests for patients with severe liver disease requiring urgent treatment . - pubmed
This simple method would provide much valuable information for the selection of therapy , prediction of impending coma and evaluation of the patient 's response to treatment , as well as an analysis of pathophysiology and prognosis . - pubmed
Postnatal development of spiral ganglion cells in the rat . - pubmed
The postnatal development of the spiral ganglion in the albino rat was studied using light and electron microscopy . - pubmed
[ Errors in the diagnosis of chronic hepatitis in children ] . - pubmed
[ Susceptibility to murine leprosy bacilli of C3H / H3 mice ( author 's transl ) ] . - pubmed
Similarly , there was no significant difference between the survival of patients with stage B or stage C tumours regardless of whether their levels of the antigen were greater or less than 10 ng / mL of plasma . - pubmed
Organ - related and malignancy - associated reactivity of cancer patients ' leucocytes : a leucocyte migration study with tumour and foetal extracts . - pubmed
Leucocytes from patients with a variety of tumours including gastric , colorectal , lung , kidney and mammary cancer , were tested in the leucocyte migration test ( LMT ) against organ - related and non - organ - related tumour and foetal extracts . - pubmed
The reactivity of cancer patients ' leucocytes against a panel of organ - related tumour extracts was found to be 71 - 93 % , depending on the tumour system tested . - pubmed
Cross - reactivity with a panel on non - organ - related tumour extracts was found in 0 - 38 % of patients . - pubmed
The result of pathologic examination indicates that Hongning Gantai can alleviate liver damages of mice and rats and thus has liver - protecting and ALT - lowering actions . - pubmed
Food allergy was investigated in 20 children with cystic fibrosis ( CF ) , who still suffered from diarrhea and failed to thrive , in spite of adequate diet and enzyme treatment ( group A ) . - pubmed
The study also included two age - matched control groups , comprising 10 CF children without intestinal symptoms and/or failure to thrive ( group B ) , and 20 healthy children ( group C ) . - pubmed
Symptoms improved in 90 % of CF patients ( group A ) when the implicated foods were eliminated from the diet and in 78 % the oral provocation test resulted positive . - pubmed
PURPOSE : The prognosis of patients with multifocal primary and early or multiple relapsed Ewing ' s sarcoma is poor with conventional chemoradiotherapy and surgery . - pubmed
Seven patients had multifocal primary Ewing ' s sarcoma , and 10 had early or multiple relapse . - pubmed
RESULTS : The probability of relapse in the study patients is 52 % at 6 years after the last event before transplantation . - pubmed
Probability of relapse - free survival in the study patients is 45 % + /- 12 % at 6 years after the last event before transplant , compared with 2 % + /- 2 % for the historic control group . - pubmed
Using a multidisciplinary approach , we have measured various indicators of DNA damage in peripheral lymphocytes of human populations potentially at increased risk for cancer . - pubmed
A prospective , longitudinal study was performed to identify environmental factors that modulate genetic damage in breast cancer patients . - pubmed
Women with benign breast masses and no apparent disease served as controls . - pubmed
A discrete group of melanin containing cells are coincident with a major reorganization of retinal ganglion cell axons in the optic nerve of Xenopus . - pubmed
A phase I clinical trial of a combination of mitoxantrone , 5 - fluorouracil , and high - dose leucovorin given on a day 1 and day 8 schedule to patients with metastatic breast cancer . - pubmed
Platelet toxicity and more profound granulocyte toxicity appeared to occur in patients with liver metastases . - pubmed
Tissue markers of potentially malignant human oral epithelial lesions . - pubmed
Current research has provided some provocative results , suggesting an association between human papillomavirus ( HPV ) and development of squamous cell tumors including oral cancer . - pubmed
However , considering the many similarities between oral and cervical oncogenesis , many of the HPV induced changes in the cervix may also be applicable to the oral mucosa . - pubmed
This paper studies the evidence for the possible role of HPV infection in oral carcinogenesis , the uterine cervix as a model for HPV mediated carcinogenesis , and tries to determine if similar mechanisms could exist in both cases . - pubmed
Islet viability was assessed by syngeneic transplantation to the renal subcapsular space of streptozotocin - induced diabetic rats . - pubmed
Twelve patients with suspected SO dysfunction were investigated . - pubmed
A study of radiation necrosis and edema in the canine brain using positron emission tomography and magnetic resonance imaging . - pubmed
Radiation injury , a major hazard of central nervous system ( CNS ) radiotherapy , was investigated using sequential studies with positron emission tomography ( PET ) and magnetic resonance imaging ( MRI ) in beagle dogs with both helium and neon - ion hemibrain irradiation . - pubmed
All dogs receiving 7.5 - 11 Gy of neon showed no signs of radiation injury to 3 years after irradiation . - pubmed
Dogs receiving & gt ; or = 13 Gy neon or helium succumbed to radiation necrosis and died 21 - 32 weeks after irradiation . - pubmed
The findings of imaging studies for all dogs who succumbed to radiation necrosis were normal until 3 - 6 weeks before death . - pubmed
The present report describes a patient with moderately severe idiopathic aplastic anaemia who was managed with intensive haematological support leading to delivery of a healthy infant by caesarean section . - pubmed
We analyzed the pattern of failure and clinicopathologic factors influencing the disease - free survival of 78 patients who died after macroscopic curative resection for pancreatic cancer . - pubmed
Local recurrence was a component of failure in 56 patients ( 71.8 % ) and hepatic recurrence in 48 ( 61.5 % ) , both accounting for 97 % of the total recurrence rate . - pubmed
From our experience and the data collected from the literature , it appears that surgery alone is an inadequate treatment for cure in patients with pancreatic carcinoma . - pubmed
In pithed Wistar Kyoto ( WKY ) and spontaneously hypertensive ( SHR ) rats , electrical ( 1 Hz , 1 ms , 50 V for 10 s ) stimulation increased diastolic blood pressure by 28 and 37 mmHg , respectively . - pubmed
The inhibitory influence of imetit was diminished by thioperamide 1 mumol / kg to about the same degree in rats of either strain . - pubmed
One patient ( 18 years old ) developed recurrence and died due to extensive infiltration into the maxilla and mandible . - pubmed
Two patients ( 57 and 62 years ) developed multiple myeloma one to two years after the excision of tumors , and both died two to three months later . - pubmed
CONCLUSION : The smears from all 13 patients were diagnosed as extramedullary plasmacytomas by fine needle aspiration cytology . - pubmed
RESULTS : Among the 512 patients were 9 with gastrinomas . - pubmed
In the second group of gastrinoma patients all had a degree of amidation of less than 50 % . - pubmed
Effect of tumor bulk on local control and survival of patients with T1 glottic cancer . - pubmed
Seventy - seven patients had small lesions and 37 had bulky tumors . - pubmed
The anterior commissure was involved with cancer in 43 patients . - pubmed
The 5 - year actuarial survival for all patients was 73 % and the disease - free survival was 92 % . - pubmed
Patients who had bulky tumors had lower local control and disease - free survival rates than those patients who had small tumors . - pubmed
Effects of Ramipril and Isradipin on hemorheological profiles in patients with arterial hypertension . - pubmed
Although in the T - IAA group 4 of the 29 patients ( 13.8 % ) displayed partial incontinence ( & lt ; 9 points ) , all of 8 patients in the DS - IAA group showed good results referring to continence ( & gt ; 10 points ) . - pubmed
Epstein - Barr virus ( EBV ) seronegativity is rare in adults . - pubmed
DNA fragmentation precedes aberrant expression of cell cycle - related protein in rat brain after MCA occlusion . - pubmed
Except for a small subset of patients with angina whose survival is improved with coronary artery bypass surgery , chronic stable angina can be appropriately managed with medical therapy in the vast majority of patients . - pubmed
Drug therapy includes aspirin , beta - adrenergic blockers , cholesterol - lowering agents and other anti - ischemic drugs that can ameliorate angina and improve the patient 's quality of life . - pubmed
Plasma homocysteine is decreased in the hypothyroid rat . - pubmed
Recent clinical studies have indicated that plasma homocysteine was significantly increased in hypothyroid patients . - pubmed
Since hyperhomocysteinemia is an independent risk factor for cardiovascular disease we investigated homocysteine metabolism in hypothyroid rats . - pubmed
Unlike the human hypothyroid patients , both groups of hypothyroid rats exhibited decreased total plasma homocysteine ( 30 % in PTU rats , 50 % in thyroidectomized rats ) versus their respective controls . - pubmed
The hypothyroid rat can not be used as a model to study homocysteine metabolism in hypothyroid patients . - pubmed
The markedly high levels of polymorphism present in classical class I loci of the human major histocompatibility complex have been implicated in infectious and immune disease recognition . - pubmed
We describe a 34 - year - old female patient with " primary antiphospholipid syndrome " and portopulmonary hypertension . - pubmed
Influence of highly active anti - retroviral therapy on response to treatment and survival in patients with acquired immunodeficiency syndrome - related non - Hodgkin ' s lymphoma treated with cyclophosphamide , hydroxydoxorubicin , vincristine and prednisone . - pubmed
We analysed the influence of HAART on the response to treatment and survival in a series of 58 patients with acquired immune deficiency syndrome ( AIDS)-related non - Hodgkin ' s lymphoma ( NHL ) treated with CHOP ( cyclophosphamide , hydroxydoxorubicin , vincristine and prednisone ) . - pubmed
Two groups of patients were included : ( i ) forty - one patients diagnosed with NHL between 1988 and 1996 who were not treated with HAART ; ( ii ) seventeen patients diagnosed since 1996 , who were receiving or commenced HAART when NHL was diagnosed . - pubmed
Improvement was observed in the group of patients with very mild to mild cognitive impairment , while in more severe dementia , the mean EGb effect should be considered more in terms of stabilization or slowing down of worsening , as compared to the greater deterioration observed with placebo . - pubmed
Mixed infection of HBV / G and HBV / A , as well as the recombination , was demonstrated in the sequence of preS1 and preS2 regions also . - pubmed
Coinfection with HBV / G and HBV / A was demonstrated in the other three patients , and their recombination in two patients . - pubmed
In conclusion , HBV / G is frequently found as a coinfection with HBV / A. - pubmed
METHODS : A total of 50 patients with clinically non - functional pituitary macroadenomas were treated by transsphenoidal tumour resection and were examined by MRI before and directly after surgery ( early MR ) and 3 months ( intermediate MR ) and 1 year after surgery ( late MR ) . - pubmed
On the intermediate MR images residual tumour tissue was detected in 30 % of the patients ( 4 intrasellar , 2 suprasellar and 9 parasellar ) . - pubmed
Before surgery the pituitary gland was visible superiorly or posterosuperiorly to the macroadenomas in 35 patients . - pubmed
Electromyographic activity associated with spontaneous functional recovery after spinal cord injury in rats . - pubmed
This investigation was designed to study the spontaneous functional recovery of adult rats with incomplete spinal cord injury ( SCI ) at thoracic level during a time course of 2 weeks . - pubmed
Directly after SCI , a marked drop in locomotor ability occurred in all rats with subsequent partial recovery over 14 days . - pubmed
Histology of a skin biopsy showed naked noncaseating granulomata and PCR for Mycobacterium tuberculosis was negative . - pubmed
We discuss the presentation and management of sarcoidosis in children , and highlight the potential difficulty in differentiating this from disseminated tuberculosis . - pubmed
METHODS : We examined 128 Czech patients with ADPKD ( 62 males , 66 females ) and 93 patients with IGAN ( 51 males , 42 females ) . - pubmed
OBJECTIVES : To investigate the effects of treatment with nebulised hypertonic saline on people with CF compared to placebo and or other treatments that enhance mucociliary clearance . - pubmed
At this stage there is insufficient evidence to support the use of hypertonic saline as routine treatment for people with cystic fibrosis . - pubmed
There were 77 persons without dementia and 51 with probable AD ; 38 participants had one or more epsilon4 alleles . - pubmed
Strain M25 extracts also contained small quantities of the streptin 1 and streptin 2 peptides in various stages of dehydration . - pubmed
Rats were perfused at 2 hours after inflammation , and brainstem tissues were processed for Fos - Fluorogold double immunocytochemistry . - pubmed
Effect of atherosclerosis and age upon the serum mucoprotein and hexosamine levels in man . - pubmed
EXPERIMENTAL MANGANESE ENCEPHALOPATHY IN MONKEYS . - pubmed
BACKGROUND AND OBJECTIVE : To evaluate the reproducibility of full - field perfusion analysis using scanning laser Doppler flowmetry ( SLDF ) for perfusion measurements of the neuroretinal rim of the optic nerve head and the peripapillary retina in patients with open - angle glaucoma or ocular hypertension , and in normal subjects . - pubmed
PATIENTS AND METHODS : SLDF perfusion measurements of the neuroretinal rim and the peripapillary retina were performed on 20 patients with open - angle glaucoma or ocular hypertension ( group G ) and 20 normal volunteers ( group N ) . - pubmed
METHODS : Two hundred twenty women , ages 18 to 49 years , with PAOD and 629 healthy women ( control group ) from a population - based case - control study filled out the same structured questionnaire and donated venous blood samples for determination of plasma homocysteine levels . - pubmed
RESULTS : Young women with hyperhomocysteinemia had a 2.5 - fold ( 95 % confidence interval [ CI ] , 1.7 - 3.9 ) increased risk for PAOD . - pubmed
METHODS : One hundred and twenty - six diabetic patients without CHD and 41 patients with CHD were recruited from our hospital . - pubmed
Transient hyperthyroidism after withdrawal of antithyroid drugs in patients with Graves ' disease . - pubmed
The development of silent thyroiditis in patients with a history of Graves ' disease is common , especially in the postpartum period . - pubmed
If such patients are diagnosed as recurrence of Graves ' disease , they may receive ATD or radioiodine therapy unnecessarily . - pubmed
We retrospectively studied 22 patients with Graves ' disease who showed transient thyrotoxicosis after withdrawal of ATD . - pubmed
Most of the 22 patients became euthyroid within 6 months . - pubmed
This study suggests a new therapeutic option as follows : in the case of young patients with mild thyrotoxicosis after withdrawal of ATD , physicians should follow them up for one month without medication unless they have unbearable symptoms or complications . - pubmed
We report here about two patients with clinically suspected diagnosis of a Takayasu ' s arteritis already under anti - inflammatory therapy in whom percutaneous transluminal atherectomy of subclavian and axillary artery stenoses was performed to relief the patients from symptoms -- intermittent dyspraxia of the arms -- and to verify the clinical diagnosis by histology . - pubmed
On the 6th postoperative day , the patient experienced tightness of the chest and nausea after receiving a transfusion of fresh frozen plasma ( FFP ) . - pubmed
Duodenal ulcers were induced in rats by cysteamine with or without CFTR ( inh )- 172 pretreatment 1 h before cysteamine . - pubmed
Human gastric cancer xenografts SC-2 , St-40 , and SC-4 inoculated into nude rats were treated with TS-1 alone ( TS-1 12 mg / kg / day , day 1 - 14 ) , TXT alone ( TXT 2 mg / kg / day , day 1 or day 8) , and combination of both drugs . - pubmed
Twenty eight people were recorded as having a total of 45 seizures ( 23 before starting bupropion , two in the first 28 days of treatment , and 20 at a later point ) . - pubmed
An 83 - year - old woman died as a result of an anastomotic dehiscence ; the six other deaths resulted of cardiopulmonary complications . - pubmed
Postoperative morbidity was 15 % ( 11 patients ) including two fistulas , which recovered without surgery . - pubmed
A randomized , double - blind , placebo - controlled trial of duloxetine in the treatment of women with fibromyalgia with or without major depressive disorder . - pubmed
This was a 12 - week , randomized , double - blind , placebo - controlled trial to assess the efficacy and safety of duloxetine , a selective serotonin and norepinephrine reuptake inhibitor , in 354 female patients with primary fibromyalgia , with or without current major depressive disorder . - pubmed
MATERIAL AND METHOD : Patients with Sicca ' s Syndrome from the Stomathology service , Santa Casa de Misericordia Hospital , in Sao Paulo , ENT Department , from July 1999 to April 2002 . - pubmed
A 70 - year - old woman with acute renal failure . - pubmed
The reason why only a few patients with multiple myeloma develop CSH , while the majority do not , is unknown , but it may at least partially reflect a defect in intralysosomal degradation because simple light chain overproduction is not sufficient for the development of CSH . - pubmed
Interestingly , CSH is associated with improved survival in multiple myeloma patients , perhaps due to earlier detection and treatment of myeloma because of the symptoms associated with CSH . - pubmed
In this case report , we discuss the presentation and management of pancreatic adenocarcinoma , with lung and liver metastases , diagnosed in a woman in her third trimester of pregnancy ( 28 weeks ) . - pubmed
In both models , and particularly in each of three , independent in vitro infection experiments , this assay permitted the quantitation of HCV replication . - pubmed
Humans can be infected with RVF virus from bites of mosquitoes or other arthropod vectors that have fed on animals infected with RVF virus , or through contact with viremic animals , particularly livestock . - pubmed
Multicolour FISH in an analysis of chromosome aberrations induced by N - nitroso - N - methylurea and maleic hydrazide in barley cells . - pubmed
METHODS : Human hepatocellular carcinoma was induced in nude mice , and the mice were randomly divided into group A receiving normal saline , group B receiving magnetic nanoparticles containing 5 - fluorouracil ( 5 - FU ) , group C receiving 5 - FU , and group D receiving magnetic nanoparticles containing 5 - FU with a magnetic field built in tumor tissues . - pubmed
Metabolic acidosis : new insights from mouse models . - pubmed
Comparative proteomic analysis of human adenomyosis using two - dimensional gel electrophoresis and mass spectrometry . - pubmed
Five of them were histologically diagnosed with adenomyosis and the other five age - matched patients had cervical carcinoma in situ . - pubmed
She had a history of infective endocarditis caused by methicillin - sensitive Staphylococcus aureus a year ago . - pubmed
Increased cardiovascular risk in patients with human immunodeficiency virus infection under highly active antiretroviral therapy . - pubmed
Unrelated umbilical cord blood transplantation using a TBI / FLAG conditioning regimen for adults with hematologic malignancies . - pubmed
CASE OUTLINE : This article presents a case of a young female with schizophrenia , without clinical improvement with several antipsychotics ( clozapine , risperidone , haloperidol ) and with the occurrence of significant neurological side effects . - pubmed
85 consecutive patients ( 90 knees ) were enrolled , who were available at 1 - year follow - up after a medial opening wedge high tibial osteotomy using a kinematic navigation system or a conventional method , for medial unicompartmental osteoarthritis . - pubmed
PATIENTS AND METHODS : Chemotherapy - naive patients with histo-/cytologically proven unresectable APC , and bi - dimensionally measurable diseases were eligible . - pubmed
However , nontuberculous mycobacterial infection diagnosed with FNAB material is much rarer , with Mycobacterium avium complex being the most common . - pubmed
When faced with antibiotic - resistant cellulitis and abscesses , the FNAB material must be sent for acid fast bacteria smears and culture . - pubmed
CONCLUSIONS : This trial of myoblast transplantation via catheter into heart failure patients demonstrated safety and feasibility . - pubmed
Treated patients showed improvement in NYHA , MLHFQ , ventricular viability , and evidence of reverse ventricular remodeling . - pubmed
Decreased cell proliferation in the dentate gyrus does not associate with development of anhedonic - like symptoms in rats . - pubmed
Nevertheless , several reports have recently pointed out that , in rodent models of depression , suppression of generation of new hippocampal neurons is not by itself sufficient to induce the development of depression - related symptoms . - pubmed
In the present study , we used the cell proliferation blocker methylazoxymethanol ( MAM ) and the rat chronic mild stress ( CMS ) model of depression to challenge the neurogenic theory of depression . - pubmed
Unlike CMS , chronic injections with MAM did not induce anhedonia - like symptoms in rats . - pubmed
Our results show that suppression of cell proliferation in the hippocampal formation is not an absolute factor for induction of an anhedonia - like state in rats . - pubmed
We found that neonatal dusky sharks ( Carcharhinus obscurus ) are not independent from maternal resource allocation at the point of parturition but instead are provisioned with energy reserves in the form of an enlarged liver that constitutes approximately 20 % of total body mass . - pubmed
Some patients need sleep therapy as well as anti - depressive therapy . - pubmed
To characterize the molecular mechanisms involved in the transition from the chronic phase to blast crisis in chronic myelogenous leukemia ( CML ) , gene expression profiles of leukemic cells from patients in the chronic and blast crisis phases were analyzed using an 8.7 K cDNA chip and real - time PCR . - pubmed
These results may help in the prediction of disease progression in CML patients and the development of more appropriate therapeutic modalities . - pubmed
All children who suffered a superficial partial - thickness scald injury were included . - pubmed
OBJECTIVE : To describe an unusual case of lateral neck swelling in a patient with a permanent cardiac pacemaker . - pubmed
CASE REPORT : We describe a patient who presented with a painful , lateral neck swelling due to an internal jugular vein thrombus . - pubmed
CONCLUSION : There was a high frequency of behavioral risk factors , together with unawareness , and very little health infrastructure , thus creating an impending risk for the rapid spread of HIV / AIDS ( acquired immunodeficiency syndrome ) . - pubmed
Optical Coherence Tomography Findings in Patients with Degenerative Retinoschisis and Symptomatic Retinal Detachment . - pubmed
This article describes the optical coherence tomography ( OCT ) findings in 4 patients with degenerative retinoschisis and symptomatic retinal detachment . - pubmed
During the last nine years ( 1986 to 1994 ) the authors treated 27 children with injuries of the proximal growth plate of the tibia , i. e. 0,8 % of all skeletal injuries treated during the above period at the clinic . - pubmed
In the total number of patients one complication of partial growth stimulation occured with a subsequent angulation deformity of the proximal tibia ( 4,5 % ) and in one instance ( 4,5 % ) an early complication in a patient with a devastating injury of the leg and dorsum of the foot where the combined affection of the popliteal artery in the dislocated fracture of the proximal epiphysis of the tibia and the devastating injury of the leg led to a subsequent uncontrollable anaerobic infection , which called for amputation of the leg . - pubmed
Tyrosine monitoring in children with early and continuously treated phenylketonuria : results of an international practice survey . - pubmed
This paper provides a snapshot of current practice in the monitoring and/or treatment of tyrosine levels in children with PKU , across 12 countries from Australasia , North America and Europe . - pubmed
[ Effect of Bushen Huoxue recipe on the state of extracellular matrix in glomerulosclerosis rats model ] . - pubmed
OBJECTIVE : To investigate the effect and acting mechanism of Bushen Huoxue Recipe ( BHR ) on the state of extracellular matrix in glomerulosclerosis ( GS ) rats model . - pubmed
Compounds show in - vitro antiproliferative activity against some human cancer cell lines . - pubmed
METHODS : Twenty varicose vein specimens were atraumatically harvested from 20 women undergoing lower extremity primary varicose vein excision . - pubmed
The patients were divided into groups according to age ( & lt;50 years , & gt;50 years ) and the presence of leg edema ( CEAP , class 2 or 3 ) . - pubmed
CONCLUSION : Age of the patient may affect the remodeling of varicose veins and SMC quantity in the media layer was found decreased in patients with edema . - pubmed
Mouse and fruit fly CD knock - out models have highlighted the multi - pathophysiological roles of CD in tissue homeostasis and organ development . - pubmed
Here we report the first phenotypic description of the lack of CD expression during zebrafish ( Danio rerio ) development obtained by morpholino - mediated knock - down of CD mRNA . - pubmed
Our findings add to the list of CD functions in organ development and patho - physiology in vertebrates . - pubmed
Francisella asiatica as the causative agent of piscine francisellosis in cultured tilapia ( Oreochromis sp . ) - pubmed
Francisella asiatica is a Gram - negative , pleomorphic , facultative intracellular , bacterial pathogen that causes acute to chronic disease in a wide variety of warm - water cultured and wild fish species . - pubmed
Outbreaks of francisellosis in warm water fish have been documented in Taiwan , Japan , United Kingdom , Hawaii , and Latin America ( including Costa Rica ) but the organism has only been reported from the United States on one occasion from hybrid striped bass in California . - pubmed
BACKGROUND : Adjuvant therapy is not usually recommended in AJCC T2N0M0 gastric cancer , yet sometimes is indicated for high - risk patients . - pubmed
METHODS : We analyzed our documented clinical database of 233 patients with T2N0M0 gastric cancer who underwent radical resection between 2000 and 2007 . - pubmed
CONCLUSION : Patients with T2N0 gastric cancer have a favorable prognosis after radical resection . - pubmed
A prognostic risk model of patients with pT2N0 gastric cancer undergoing radical resection is constructed based on lymphatic and/or blood vessel invasion , tumor diameter , and perineural invasion . - pubmed
The prognostic risk model identifies a small subgroup of patients with an increased risk of death , suggesting adjuvant therapy may be considered for these patients . - pubmed
Over the last decade , several rhythm - versus rate - control trails in patients with atrial fibrillation ( AF ) have failed to demonstrate benefit of the rhythm control strategy with respect to mortality and morbidity . - pubmed
Currently , dronedarone is the only available antiarrhythmic drug which has shown a reduction in cardiovascular hospitalizations in medium - risk AF patients . - pubmed
However , the drug was associated with increased mortality in patients with recently decompensated heart failure . - pubmed
Hence , antiarrhythmic drug therapy has to be evaluated in patients with AF on an individual patients basis . - pubmed
These are important considerations for communities hard - hit by HIV and AIDS , given the extent and nature of deprivation , the long - term risk to human capital and the current political willingness to act . - pubmed
We report the case of a 45 - year - old woman with chronic HIV infection and personality disorder , who after 12 months of tenofovir , complained of fatigue , diffuse bone pain and gait disturbances . - pubmed
Vascular restenosis is affecting 30 - 40 % of patients treated by percutaneous coronary angioplasty ( PTCA ) . - pubmed
Alpha - lipoic acid ( ALA ) , a natural antioxidant , is widely used for the treatment of some diseases including diabetes , and decursinol ( DA ) , a constituent of root of Angelica gigas Nakai , has some pharmacological activities including anti - inflammatory function . - pubmed
Included are 680 ADPKD adults who provided data on blood pressure , renal volume , renal function , uric acid , age at the onset of ESRD or last known age without ESRD . - pubmed
The study includes 10 non - pregnant women , 50 normal pregnancy , and 110 preeclamptic ( PE ) women at the same period of pregnancy . - pubmed
Efficacy and safety of oral chelators in treatment of patients with Wilson disease . - pubmed
We assessed the safety of D - penicillamine and trientine therapy and outcomes of patients with Wilson disease . - pubmed
METHODS : We performed a retrospective analysis of data on 380 patients with Wilson disease from tertiary care centers in Germany and Austria , and 25 additional patients from the EUROWILSON registry . - pubmed
Forty - eight months after therapy , hepatic deterioration was reported in only 4 of 333 patients treated initially with a chelating agent . - pubmed
However , neurologic deterioration was observed less frequently in patients given D - penicillamine first ( 6 of 295 ) than those given trientine first ( 4 of 38 ; P = .018 ) . - pubmed
CONCLUSIONS : Chelating agents are effective therapies for most patients with Wilson disease ; D - penicillamine and trientine produce comparable outcomes , although D - penicillamine had a higher rate of adverse events . - pubmed
Few patients receiving chelation therapy had neurologic deterioration , which occurred more frequently in patients who received trientine . - pubmed
Patients consistently treated with European AIDS Clinical Society ( EACS ) 2008 guidelines were 255 ( 76.6 % ) , of whom 202 ( 79.2 % ) with an indication to an anti - HIV treatment , 30 ( 11.8%)without an indication , and 21 ( 8.2 % ) with cirrhosis . - pubmed
Previous anti - HBV treatment ( p = 0.01 ) and a triple HDV co - infection ( p = 0.03 ) reduced the chance of not - consistent regimens . - pubmed
To the best of our knowledge , this is the first study using barcoded DNA pyrosequencing method to survey the ileal microbiome of goats and the results suggest that increasing levels of dietary corn change the composition of the ileal bacterial community . - pubmed
This study investigated long - term cellular and humoral immunity against pertussis after booster vaccination of 4 - year - old children who had been vaccinated at 2 , 3 , 4 , and 11 months of age with either whole - cell pertussis ( wP ) or acellular pertussis ( aP ) vaccine . - pubmed
CDAD was defined as & gt;=3 episodes of loose stools in & lt;24 h with a positive Clostridium difficile stool toxin assay . - pubmed
Bleeding complications in patients with coronary stents during non - cardiac surgery . - pubmed
The type of procedure , perioperative antiplatelet therapy , and other patient - related factors influence the risk of postoperative haemorrhage . - pubmed
Our objective was to analyze the postoperative risk factors for hemorrhagic complications and to determine the impact of antiplatelet and anticoagulant therapy strategies on postoperative bleeding risk in patients with coronary stents undergoing non - cardiac surgery . - pubmed
RESULTS : Among the 1134 patients evaluated , 108 ( 9.5 % ) experienced a postoperative hemorrhagic complication ( with a median time to occurrence of 5.3days ) . - pubmed
Mortality in patients with a haemorrhagic complication was 12 % ( n=13 ) . - pubmed
When interrupted before the procedure , resumption of antiplatelet treatment was delayed in patients developing early postoperative hemorrhagic complications . - pubmed
CONCLUSION : Patients with coronary stents who undergo surgery are at high risk for hemorrhagic complications . - pubmed
Bazedoxifene versus oral bisphosphonates for the prevention of nonvertebral fractures in postmenopausal women with osteoporosis at higher risk of fracture : a network meta - analysis . - pubmed
OBJECTIVE : To compare the efficacy of bazedoxifene and oral bisphosphonates for the prevention of nonvertebral fractures ( NVFs ) in women with higher risk of postmenopausal osteoporosis ( i.e. - pubmed
A subgroup of patients with a FRAX score of 20 % or more in the bazedoxifene phase III osteoporosis study was selected as the population of interest on the basis of the bazedoxifene label . - pubmed
PE / ARDS alone in Plasmodium vivax may result in mortality , whereas multiorgan involvement is common in P. - pubmed
Association of Epstein Barr virus A73 gene polymorphism with nasopharyngeal carcinoma . - pubmed
METHODS : A case - control study was designed , including 510 nasopharyngeal cancer patients and 520 healthy controls , A157154C genotypes of the A73 gene in EB virus were detected , genotype and allele frequency distribution between the two groups were compared . - pubmed
The present study was undertaken to evaluate the antinociceptive properties of physalins B ( 1 ) , D ( 2 ) , F ( 3 ) , and G ( 4 ) isolated from Physalis angulata in inflammatory and centrally mediated pain tests in mice . - pubmed
Here , we report a rare case of Sweet ' s syndrome induced by azathioprine in a patient with Crohn ' s disease . - pubmed
Efficacy of chlorhexidine and green tea mouthwashes in the management of dental plaque - induced gingivitis : A comparative clinical study . - pubmed
The antibacterial and antioxidant properties of green tea were found to be beneficial in the treatment of gingival and periodontal diseases . - pubmed
The aim of this comparative study was to compare the efficacy of the mouthwash containing green tea and chlorhexidine in the management of dental plaque - induced gingivitis . - pubmed
However , green tea mouthwash resulted in a statistically significant decrease in bleeding index compared to chlorhexidine group . - pubmed
CONCLUSION : The green tea - containing mouthwash is equally effective in reducing the gingival inflammation and plaque to chlorhexidine . - pubmed
METHODS : Patients with STEMI treated with thrombolysis followed by percutaneous coronary intervention ( PCI ) were randomly assigned to receive either BMMNC or saline as an intracoronary injection . - pubmed
We compared the lomustine , cytarabine , cyclophosphamide and etoposide ( LACE ) and BCNU , etoposide , cytarabine , melphalan ( BEAM ) conditioning regimens for toxicity , engraftment kinetics , and efficacy in 139 patients undergoing autologous hematopoietic stem cell transplant for primary refractory or relapsed lymphoma . - pubmed
Ninety - two patients with Hodgkin lymphoma and 47 with non - Hodgkin lymphoma were enrolled . - pubmed
It was related most closely to the type strain of Sedimentibacter saalensis ( 94 % sequence similarity ) . - pubmed
The type strain is MO - SEDIT ( = JCM 17293 T = DSM 24004 T ) . - pubmed
OBJECTIVE : To assess the ability of semen analysis and other patients ' characteristics to predict the presence of spermatozoa in radical orchiectomy pathological specimen , and describe potential implications for patients with azoospermia and testis cancer . - pubmed
PATIENT(S ): A total of 214 consecutive patients with testicular cancer who underwent radical orchiectomy between 1997 and 2015 . - pubmed
Given the substantial likelihood ( ~60 % ) of spermatozoa to be present in the cancerous testis of patients with azoospermia and cryptozoospermia , concomitant oncologic testicular sperm extraction ( TESE ) can be considered in these selected patients . - pubmed
OBJECTIVE : In patients with subpulmonic infundibular ventricular septal defect ( VSD ) , postoperative progression of aortic regurgitation ( AR ) sometimes occurs despite early operation before the development of AR . - pubmed
CONCLUSIONS : Among patients with subpulmonic infundibular VSD , the incidence of late AR progression after VSD repair alone was unexpectedly high ( 7.7 % ) . - pubmed
Children aged 2 - 18 years ( N = 108 ) with suspected OSA underwent overnight simultaneous oximetry and actigraphy at home on a single night . - pubmed
Diagnostic value of trunk flexion - extension testing in old chronic low back pain patients . - pubmed
PURPOSE : Dynamic trunk flexion - extension testing has been proven to objectively diagnose low back pain in persons under the age of 60 years but older persons have difficulty complying with standardized movement velocity . - pubmed
A 48 - year - old woman underwent a total abdominal hysterectomy after preoperative diagnosis of multiple uterine leiomyomas . - pubmed
The patient was also diagnosed with pelvic bone metastasis and received six cycles of adjuvant chemotherapy with gemcitabine plus docetaxel and local radiation therapy to control the pain . - pubmed
The patient underwent a craniotomy and resection of the lesion , which was a confirmed metastasis from uterine LMS by histopathology . - pubmed
One month after the craniotomy , the patient experienced lower abdominal pain , and a pelvic metastasis was detected . - pubmed
METHODS AND MATERIALS : Six consecutive clinical stage I , grade 1 - 2 , medically inoperable endometrial cancer patients were treated with triple - tandem HDR brachytherapy . - pubmed
We report patient factors and acute toxicity . - pubmed
Patient comorbidities included morbid obesity , congestive heart failure , diabetes , and pulmonary emboli . - pubmed
CONCLUSIONS : In medically inoperable , clinical stage I endometrial cancer patients with multiple comorbidities , definitive triple - tandem , HDR brachytherapy results in mild acute toxicity . - pubmed
An unexpected finding in a man with multiple pulmonary nodules , a pleural effusion and respiratory failure . - pubmed
We report the case of a 47 - year old Caucasian man with a history of depression and high alcohol intake who presented with a one - month history of weight loss , dry cough and abdominal pain . - pubmed
We discuss this unexpected finding and review the literature on Bovine Tuberculosis in humans . - pubmed
METHODS : We re - abstracted the medical records of a random sample ( n = 520 ) of metastatic melanoma patients who had been diagnosed in 2011 and reported to population - based registries in the U.S. We also queried their treating physicians . - pubmed
Records of children treated for achalasia , over an 18 - year period , were reviewed . - pubmed
Twenty - eight patients were initially treated with Heller 's myotomy ( HM ) and 20 with balloon dilatation ( BD ) . - pubmed
All children who underwent BD required HM due to symptom recurrence . - pubmed
Of 108 procedures , esophageal perforation occurred in two children after HM ( two out of 48 HM procedures in total , 4 % ) and one child after BD ( 1/60 , 1.7 % ) . - pubmed
CONCLUSION : Less than half of children with achalasia are symptom free after initial treatment with either BD or HM . - pubmed
METHOD : We conducted a 6 - year prospective observational study on 20 pregnant women in whom uncomplicated simple appendicitis ( appendiceal diameter & lt;=11 mm and with no signs of appendicoliths , perforation , or abscess ) was radiologically verified and managed with a 4 - day course of antibiotics . - pubmed
Three patients failed to respond to antibiotic therapy during hospitalization and underwent subsequent appendectomy ( 2 suppurative and 1 perforated appendicitis ) . - pubmed
Inclusion criteria were treatment - naive children with isolated nonsyndromic trigonocephaly , being treated with standardized frontoorbital advancement in our department . - pubmed
One patient suffered from a small inconsequential subdural hematoma . - pubmed
Another patient suffered from dural tears , which were identified and treated intraoperatively . - pubmed
A meta - analysis of trials testing blood pressure management among nondialysis - dependent CKD patients ( 15 924 total patients ) found more intensive therapies generally reduced mortality in all subgroups . - pubmed
As a result of the unavailability of genetics , the infection process of R. - pubmed
distachyon provides a genetic resource that can confer disease resistance against R. - pubmed
We hypothesize that interventions increasing muscle strength might propagate to motor units at the abductor pharyngeal muscles , reducing collapsibility and , hence , sleep apnea severity in elderly patients with obstructive sleep apnea . - pubmed
METHODS / DESIGN : This is a randomized clinical trial including patients between 65 and 80 years of age , with obstructive sleep apnea , and an apnea - hypopnea index ( AHI ) between 20 and 50 events / hour , diagnosed by out - of - center in - home type III polysomnography . - pubmed
METHODS : We retrospectively studied the outcomes of patients who underwent RA at our institute for heavily calcified , balloon - uncrossable or - undilatable SB lesions over an approximately 5 - year period ( January 2011 to September 2016 ) . - pubmed
RESULTS : Two hundred and forty - four patients underwent main vessel only RA ( SB - MV + RA group ) and another 48 patients underwent SB RA ( SB + MV + - RA group ) for 49 side branches . - pubmed
However , patients underwent SB RA experienced more SB perforations and greater acute contrast - induced nephropathy ( CIN ) . - pubmed
Among the SB RA patients , 30 ( 62.5 % ) underwent RA for both SB and MV ( SB + MV + RA subgroup ) , whereas the other 18 underwent SB only RA ( SB + MV - RA subgroup ) . - pubmed
CASE PRESENTATION : We describe the case of a 41/2 -year - old boy not previously known to be a diabetic who presented to the plastic surgery department for gangrene of the left middle finger with surrounding erythema and induration . - pubmed
Effect of electron beam and gamma radiation on drug - susceptible and drug - resistant Listeria monocytogenes strains in salmon under different temperature . - pubmed
AIMS : To investigate the effect of gamma radiation and high energy electron beam doses on the inactivation of antibiotic - susceptible and antibiotic - resistant Listeria monocytogenes strains inoculated on the surface of raw salmon fillets stored at different temperature ( -20 , 4 and 25 C ) . - pubmed
Methods : The study group consists of 25 patients with nonhealing corneal ulcers due to herpes simplex or herpes zoster infection and facial nerve or trigeminal nerve paralysis as a result of a neurosurgical operation caused by a tumour or stroke . - pubmed
Complete healing of the ulceration was observed in 20 patients ( 80 % ) . - pubmed
Four patients ( 16 % ) experienced considerable improvement of their clinical condition ( reduced size and depth of the ulceration and inflammatory state : smaller conjunctival injection and swelling , improved visual acuity , and less subjective symptoms ) . - pubmed
In all patients , the progression of corneal thinning was stopped . - pubmed
Systemic Toxicity of Smokeless Tobacco Products in Mice . - pubmed
However , little is known about the systemic and cardiovascular toxicity of smokeless tobacco exposure . - pubmed
Suppression of the circulating levels of immune cells upon exposure to smokeless tobacco products may increase the susceptibility to secondary infection . - pubmed
The present study used functional magnetic resonance imaging to investigate the impact of life trauma on basal cortisol levels and neural responses to acute stress in 73 healthy individuals during brief stress and neutral - relaxing imagery using a well - established , individualized imagery method . - pubmed
BACKGROUND : Seymour fractures are distal phalanx fractures in children with a juxta - epiphyseal pattern . - pubmed
METHODS : We performed a retrospective study of patients under 18 years old treated at a large pediatric hospital from 2009 to 2017 for an acute Seymour fracture . - pubmed
RESULTS : Mean age of patients was 10 years , with 43 males and 22 females sustaining 65 Seymour fractures . - pubmed
Four patients initially managed in the ED required an unplanned operation , usually because of fracture redisplacement . - pubmed
For patients with head and neck cancer requiring a maxillectomy , obturator prostheses help with quality of life . - pubmed
Treatment sequelae can leave patients with difficulty speaking and swallowing , reduced salivary function , reduction in maximal incisal opening , and at risk of osteoradionecrosis . - pubmed
Fifty - six percent are male , 85 % Caucasian , 30 % have a history of chronic HCV and 71 % have compensated cirrhosis . - pubmed
Functional Subunit Reconstruction of Giant Facial Congenital Melanocytic Nevi in Children With the Use of Matriderm and Skin Graft : Surgical Experience and Literature Review . - pubmed
Introduction : Facial giant congenital melanocytic nevus represents a major cosmetic deformity for the child and parents and is a challenge for the plastic surgeons to achieve best cosmetic results . - pubmed
Methods : An 8 - year - old boy presented with a facial giant congenital melanocytic nevus without leptomeningeal involvement . - pubmed
The postoperative result was satisfactory with minimal residual nevus around the eye , and the patient was fully satisfied with the cosmetic and functional results . - pubmed
A case of early gastric cancer in a patient with splenic vein angioplany . - pubmed
The aim of this study was to evaluate the cytotoxicity , on human chondrocytes , of TXA at different concentrations and times of exposure and the mechanisms of cell death . - pubmed
OBJECTIVES : This systematic review and meta - analysis aimed to investigate the efficacy and safety of VPA in patients with SMA . - pubmed
METHODS : Eleven databases were systematically searched on 30 May 2017 for clinical trials that reported the efficacy and safety of VPA in SMA patients . - pubmed
Tuberculosis caused by Mycobacterium tuberculosis ( M. - pubmed
The key to reduce the spread and mortality rate of tuberculosis is to develop faster and more sensitive approaches for detection of M. - pubmed
[ Effects and mechanism of fecal transplantation on acute lung injury induced by lipopolysaccharide in rats ] . - pubmed
LPS group and LPS+FMT group were intraperitoneally injected with LPS to generate rat ALI model . - pubmed
Calcium overload - induced arrhythmia is suppressed by farnesol in rat heart . - pubmed
Therefore , one can suggest that azoramide , as a novel regulator , can provide direct cardioprotection in the IR - heart , at most , via affecting mitochondria and can be a good candidate as a new drug for the treatment of IR - associated cardiovascular disorders in mammalians with systemic IR . - pubmed
Subtotal calvarial vault reconstruction utilizing a customized polyetheretherketone ( PEEK ) implant with chimeric microvascular soft tissue coverage in a patient with syndrome of the trephined : A case report . - pubmed
However , successful reconstruction may be difficult in patients with complex and/or hostile calvarial defects . - pubmed
Based on our findings , we advocate delayed alloplastic implantation with total vascularized soft tissue coverage as a viable alternative for reconstructing extensive , hostile calvarial defects in patients with the syndrome of the trephined . - pubmed
OBJECTIVES : The present study evaluates the prognostic value of metabolic parameters related to the primary tumor identifiedin preoperative fluorodeoxyglucose ( FDG ) positron emission tomography ( PET)/computed tomography ( CT ) scans inpatients with endometrial cancer ( EC ) . - pubmed
RESULTS : The study included 120 patients with EC with a mean age of 62.3 + - 0.02 years . - pubmed
Of the total , 32 patients diedaround the time of the analysis and 38 patients showed disease progression . - pubmed
No significant relationship was identified between the SUVmax , SUVmean , MTV , TLGvalues , patient age , tumor size , histology , grade and MI degree , and OS or PFS . - pubmed
Arterial reconstruction with donor iliac vessels during kidney transplantation in a patient with severe atherosclerosis . - pubmed
Atherosclerosis is common in patients with end - stage renal disease . - pubmed
Symptomatic improvement in nasal obstruction was found to be consistently better in group A patients at postoperative days 7 and 15 , but both groups achieved comparable symptom relief at the third month . - pubmed
Oral Antiplatelet Drug Therapy on Posterior Circulation Infarction in Patients With Acute Intracranial Atherosclerosis - Related Vertebrobasilar Artery Occlusion . - pubmed
This study compared recanalization rates , symptomatic intracranial hemorrhage ( SICH ) , 90 day mortality , and functional outcomes between periprocedural tirofiban and antiplatelet therapy in patients with acute intracranial atherosclerosis - related vertebrobasilar artery occlusion . - pubmed
Methods : A total of 105 consecutive patients with acute intracranial atherosclerosis - related vertebrobasilar artery occlusion who underwent EVT + tirofiban + oral antiplatelet or EVT + oral antiplatelet therapy at the Beijing Tiantan Hospital between January 2012 and July 2018 were included . - pubmed
RT was interrupted / delayed in seven patients ( 16 % ) for suspected COVID-19 infection . - pubmed
Previous coronavirus outbreaks such as severe acute respiratory syndrome coronavirus can cause new - onset diabetes mellitus ( DM ) . - pubmed
This first - in - human study evaluated MEDI0562 in adultswith advanced solid tumors . - pubmed
EXPERIMENTAL DESIGN : In this phase I , multicenter , open - label , single - arm , dose - escalation ( 3 + 3 design ) study , patients received 0.03 , 0.1 , 0.3 , 1.0 , 3.0 , or 10 mg / kg MEDI0562 through intravenous infusion every 2 weeks , until confirmed disease progression or unacceptable toxicity . - pubmed
Treatment - related adverse events ( TRAEs ) occurred in 67 % of patients , most commonly fatigue ( 31 % ) and infusion - related reactions ( 14 % ) . - pubmed
Grade 3 TRAEs occurred in 14 % of patients with no apparent dose relationship ; no TRAEs resulted in death . - pubmed
Data collected included patient demographics , level of block , type and volume of local anesthetic , occurrence of pleural puncture , occurrence of pneumothorax , evidence of local anesthetic toxicity , and patient vital signs . - pubmed
Zero pleural punctures were identified during block performance ; however , two patients were found to have a pneumothorax on postoperative chest X - ray ( 3.6 per 1000 surgeries , 95 % CI 0.5 to 13.6 ; 0.9 per 1000 levels blocked , 95 % CI 0.1 to 3.3 ) . - pubmed
Background : Monoclonal antibodies are a relatively new therapeutic option for patients with severe refractory asthma , which can be used as an add - on to maintenance therapy , reducing the need for systemic corticosteroid usage , improving asthma symptom control and reducing exacerbations . - pubmed
We report a case of a patient with severe refractory eosinophilic asthma , reluctant to take systemic steroids , who was successfully treated with benralizumab alone during an acute asthma attack . - pubmed
Case presentation : A 59 - year - old Caucasian woman with a history of allergic asthma since childhood showed a progressive decline in lung function with difficult to control symptoms and an increased number of hospitalizations despite maximal maintenance treatment , and was diagnosed with severe refractory asthma . - pubmed
Sixty - one patients were diagnosed with NF and 28 with SC . - pubmed
The algorithm accurately diagnosed all 15 NF patients with a high ( > = 8) laboratory risk indicator for necrotizing fasciitis ( LRINEC ) score . - pubmed
This study aimed to investigate the prognostic role of circulating miR-146a in the prediction of early response to imatinib treatment in patients with chronic myeloid leukemia ( CML ) . - pubmed
Sixty patients with CML and 20 healthy controls were recruited in this study . - pubmed
This study reported for the first time that measurement of the circulating miR-146a expression at 14 days can predict the early response to imatinib treatment in patients with CML . - pubmed
METHODS : Between January 2010 and December 2013 , 134 patients underwent arthroscopy and stabilization for recurrent anterior dislocation of shoulder . - pubmed
Out of total 40 patients in the curettage group , 6(15 % ) patients had recurrence of dislocation and none had subluxations , whereas in the non - curettage group 13(32.5 % ) patients had recurrence of dislocation and 3(7.5 % ) had subluxations . - pubmed
Challenges with co - amplification of microbial DNA in interpretation of STR profiles obtained from human skeletal remains . - pubmed
TAK-242 ameliorates olfactory dysfunction in a mouse model of allergic rhinitis by inhibiting neuroinflammation in the olfactory bulb . - pubmed
OBJECTIVE : Olfactory dysfunction ( OD ) is a common symptom of allergic rhinitis ( AR ) that can seriously affect patient quality of life ; however , the associated pathogenesis remains unclear . - pubmed
Cisplatin is a widely used , highly effective antitumor drug , but some patients have experienced irreversible hearing loss as a result of its application . - pubmed
Masked high progesterone levels during in vitro fertilization and embryo transfer treatment in a patient with 21 - hydroxylase deficiency : A case report . - pubmed
Here , we report on an infertile woman with 21OHD who initially showed normal progesterone levels and spontaneous ovulation with the treatment by an endocrinologist . - pubmed
The case underlines that close coordination is required between the endocrinologist and reproductive specialist for the total treatment for woman with 21OHD . - pubmed
Influence of the cribriform degeneration ( cri ) mutation on audiogenic seizures in DBA/2J mice . - pubmed
Effects of individual inhalation of aerosolized amantadine hydrochloride in mice infected with influenza virus A / Bethesda 10/63 ( H2N2 ) and A / Hong Kong 1 / 68 ( H3N2 ) . - pubmed
Clinical and laboratory diagnosis of enterotoxemia of cattle . - pubmed
Bone scans using 99mTc polyphosphate have been obtained in 174 patients with newly diagnosed carcinoma of the breast . - pubmed
In nine patients , the roentgenograms were abnormal , but in 18 , there was scintiscan evidence of metastatic disease involving bone , although one false - negative interpretation is included in this number . - pubmed
In another eight patients with normal or equivocal initial bone scintiscans , metastatic disease involving bone developed during a 12 months ' period of observation . - pubmed
Spinal cord stimulation ( SCS ) of the low thoracic spinal epidural space was carried out in 11 patients with pain from peripheral arterial disease of the lower limbs . - pubmed
Evidence of rat stem cell engraftment , strain - specific transplantation tolerance , and skin - specific antigens . - pubmed
This model for mixed xenogeneic chimerism with reliably detectable rat lymphoid cells may provide a model to study the existence of tissue - specific antigens across a species barrier , as well as mechanisms responsible for the induction and maintenance of this strain - specific transplantation tolerance . - pubmed
Despite the not - inconsiderable financial , material and human resources that have so far been made available -- mostly from outside the country -- only a small percentage of the presumptive number of leprosy sufferers are receiving an adequate , modern combination therapy . - pubmed
The influence of eye colour on susceptibility to TTS in humans . - pubmed
In order to investigate the function of the inner ear melanin , noise - induced temporary hearing loss ( temporary threshold shift , TTS ) was studied in humans with either blue or brown iris colour . - pubmed
Twenty - five patients with myocardial infarction were monitored in the acute phase and during follow - up with regard to the in vivo production of prostacyclin ( PGI2 ) and thromboxane ( TxA2 ) , by measurement of their major urinary metabolites , 2,3 - dinor-6 - keto - PGF1 alpha and 2,3 - dinor - TxB2 , respectively . - pubmed
In approximately 24 % of patients the in vivo production of prostacyclin did not increase during the acute phase of the infarction process . - pubmed
At the follow - up 2 years after the myocardial infarction , eight cardiac events had occurred , all of which were noted among patients who exhibited an expected increase in prostacyclin production in association with the infarction . - pubmed
This would seem reasonable , since most of the patients in this group had larger primary infarctions . - pubmed
The resultant TCGF - activated EAL cells from cancer patients significantly exceeded lytic activity of TCGF - activated EAL cells from patients with liver cirrhosis for control ( p less than 0.01 ) . - pubmed
Animals were sacrificed on Postoperative Days 1 , 2 , 4 , 7 , and 11 and the wounds were studied . - pubmed
We have studied the transport of ions in the small and large intestines of CF patients . - pubmed
A modification of Mason 's vertical banded gastroplasty for morbid obesity is presented , along with experience from 62 treated patients . - pubmed
Subcutaneous wound infection occurred in two patients . - pubmed
Three series of seven hypertensive rats ( SHR ) were used . - pubmed
Intranigral injection of dynorphin-1 - 13 exerted a potent seizure suppressant action in kindled rats . - pubmed
A 47 - year - old man developed an acute infectious mononucleosis - like illness with a moderate lymphocytosis and numerous atypical lymphocytes in the peripheral blood . - pubmed
Plasmodium falciparum : induction of resistance to mefloquine in cloned strains by continuous drug exposure in vitro . - pubmed
Pets and grass pollen allergenicity was more common among whites while allergy to Aspergillus fumigatus and Ascaris lumbricoides was found more frequently among coloured patients . - pubmed
Effect of lifetime administration of dimethylaminoethanol on longevity , aging changes , and cryptogenic neoplasms in C3H mice . - pubmed
The effects of lifetime treatment with dimethylaminoethanol on longevity and cryptogenic neoplasm formation were studied in females of two mouse sub - lines , the C3H / HeN which carries a germinal mammary tumor provirus and the C3H / HeJ(+ ) which also carries the exogenous mammary tumor virus . - pubmed
Among untreated C3H / HeJ(+ ) females , 89 % developed neoplasms of the mammary gland , ovary , liver , lung and reticuloendothelial system , while the incidence was 88 % in the treated mice . - pubmed
In C3H / HeN females , neoplasms of the mammary gland , ovary , liver , lung and lymphatic system occurred in 57 % and in 60 % of treated mice . - pubmed
Also , there was no statistically significant difference between control and treated animals in the age of onset or the type of specific neoplasms . - pubmed
Three patients are presented as illustrative examples of severe necrotizing pancreatitis associated with diuretic therapy . - pubmed
Dose of cat ( Felis domesticus ) allergen 1 ( Fel d 1 ) that induces asthma . - pubmed
All patients developed rhinitis and asthma during exposure . - pubmed
Five consecutive patient groups undergoing coronary bypass surgery were studied for postoperative conduction disturbances and atrial arrhythmias . - pubmed
Aggregation and secretion of washed platelets from stroke - prone spontaneously hypertensive rats ( SHRSP ) were greatly reduced by the development of the hypertension compared with those of platelets from age - matched normotensive Wistar - Kyoto rats ( WKY ) . - pubmed
Danazol has recently been reported to be an effective mode of treatment for patients with refractory immune thrombocytopenic purpura . - pubmed
Posthypoglycemic hyperglycemia in diabetic children . - pubmed
The occurrence of SV40 - Neutralizing antibodies in sera of patients with genitourinary carcinoma . - pubmed
Caloric regulation and food preference in normal , hyperphagic , and aphagic rats . - pubmed
[ Changes in the mean erythrocyte volume as an index of water metabolism in patients with glaucoma ] . - pubmed
In five infants with congenital defects of the brain and complete absence of temperature control there was no sweat response to thermal or direct chemical stimulation of the glands.6 . - pubmed
Pharmacokinetics of indocyanine green in rats with chronic renal failure . - pubmed
Similarly , most patients had long - lasting nasal airway improvement and reduction or elimination of recurring sinusitis . - pubmed
Although aspirin sensitivity was associated with some of the more severe asthmatic patients , it appeared not to be a factor in the responses to surgical treatment . - pubmed
Four disclosant dyes were tested for antimicrobial activity against 27 oral reference strains and five non - oral human pathogens . - pubmed
Methods of mastitis control that are effective against Streptococcus agalactiae and Staphylococcus aureus have been developed and proven successful . - pubmed
The total extent of their present involvement in mastitis is not well documented , and this is due in part to differences in the nature of infection by environmental pathogens compared to Streptococcus agalactiae and Staphylococcus aureus infections . - pubmed
Hearing loss in dogs after lesions of the brachium of the inferior colliculus and medial geniculate . - pubmed
Bilateral section of the brachium of the inferior colliculus consistently resulted in an average hearing loss of as much as 37 dB in the midrange of the animals ' audiograms . - pubmed
All strains , with the exception of M. - pubmed
Total ischemia in dog hearts , in vitro . - pubmed
[ Effect of serum glucose on the function of pancreatic exocrine in diabetic rats ] . - pubmed
These results indicated that hyperglycemia might be one of the reasons which cause the dysfunction of pancreatic exocrine in diabetic rats . - pubmed
Peripheral giant cell granuloma : a clinical study of 77 cases from 62 patients , and literature review . - pubmed
DESIGN : We reviewed retrospectively 77 cases of PGCG from 62 patients , from our files with respect to incidence , sex , patient age , race , clinical symptoms and signs , radiographic features and recurrence following excision . - pubmed
OBJECTIVE : The aim was to examine the effects of the Na+/H+ exchange inhibitors amiloride and methylisobutyl amiloride ( MIA ) in buffer perfused rabbit hearts subjected to one hour of normothermic ischaemia ( 37 degrees C ) followed by reperfusion . - pubmed
CONCLUSION : This study shows for the first time that both of the Na+/H+ exchange inhibitors amiloride and MIA produce improved recovery of ventricular function in rabbit hearts subjected to ischaemia and reperfusion , although the beneficial effect was not obtained with drug administration at the time of reperfusion only . - pubmed
Because of the risk that some patients with chronic neutropenia may have or develop myelodysplasia and/or leukemia , careful pretreatment evaluations ( blood , bone marrow and cytogenetics ) and long - term observations are extremely important . - pubmed
An international registry for patients with SCN has been established to maintain records and further investigate these conditions . - pubmed
In 115 predominantly lithium - refractory inpatients , neurologic findings were recorded , and blind raters assessed valproate response from the medical record . - pubmed
Patients with a seizure history were much more likely to have a robust response to valproate ( 70 % ) , when compared with patients without such history ( 34.6 % ) . - pubmed
History of head injury and abnormal electroencephalographic findings also tended to be more common in those patients with good response . - pubmed
Overall , the group of patients with any neurologic abnormality exhibited a significantly higher rate of good response to valproate ( 43.6 % ) than did the neurologically normal group ( 24.3 % ) . - pubmed
Bipolar or schizoaffective patients with abnormal neurologic features may represent a distinct subtype of illness and appear to be good candidates for valproate therapy . - pubmed
Adult spontaneously hypertensive rats ( SHR ) and Wistar - Kyoto ( WKY ) rats were anesthetized with halothane and artificially ventilated . - pubmed
Cell extracts from a variety of cell lines , myeloid , T , B , mastocytoma , fibroblast , melanoma and breast carcinoma of human , mouse and guinea pig promoted the growth of a wide variety of cell types , namely human myeloid cells HL-60 , human B cells Daudi , human melanoma cells A375 - C6 , mouse transformed - fibroblast cells L929 , human myelomonocytic cells THP-1 . - pubmed
tuberculosis that is correlated with growth rate in mouse spleen and lung tissue , to the avirulent strain H37Ra by complementation . - pubmed
tuberculosis strain H37Rv was constructed and transformed into H37Ra . - pubmed
In sixty patients treated with chloroquine ( Nivaquine ) 73 % showed keratopathy . - pubmed
The sequential changes of the activity of peroxide metabolism enzymes and thiobarbituric acid reaction substance ( TBARS ) as an indicator of lipid peroxide concentration were observed to analyze the mechanisms of tissue injury due to the administration of paraquat in DDY mice . - pubmed
Tumor - cell DNA content predicts outcome in children and adolescents with clinical group III embryonal rhabdomyosarcoma . - pubmed
The Intergroup Rhabdomyosarcoma Study Committee of the Children 's Cancer Group and the Pediatric Oncology Group . - pubmed
PURPOSE : The prognostic value of tumor - cell DNA content ( ploidy ) was evaluated in children with unresectable , nonmetastic rhabdomyosarcoma of embryonal histology . - pubmed
PATIENTS AND METHODS : Flow - cytometric techniques were used to estimate the ploidy of tumor specimens from 34 patients with embryonal rhabdomyosarcoma who were enrolled in the intergroup rhabdomyosarcoma study III ( IRS III ) from 1985 to 1991 . - pubmed
Significantly more children with hyperdiploid tumors achieved a complete response than did children with diploid tumors ( 85 % v 42 % ; P = .01 ) . - pubmed
CONCLUSION : Tumor - cell ploidy strongly correlates with outcome in children with nonmetastic , unresectable embryonal rhabdomyosarcoma . - pubmed
In psychometric testing , there was no marked depressive syndrome in the HIV - positive individuals , but a mild slowing of speed - dependent abilities . - pubmed
It has been reported that SCID ( severe combined immunodeficiency , scid / scid ) mice are more radiosensitive than normal mice . - pubmed
Furthermore , this less sensitive fraction might be a source of the " leaky " change of T and B cells , possibly due to the induction of an equivocal repair system which appears in the later stages of life in the SCID mice . - pubmed
These patients represented 10 % of all drug overdoses admitted over the same period . - pubmed
An acute ( 48 - hr ) lethal toxicity study of turbot at various stages from hatch to juveniles showed that prior to first exogenous feeding , larvae of turbot were an order of magnitude more sensitive to cadmium toxicity than later developmental stages ( LC50 of 0.18 - 0.23 ppm Cd versus 2 - 5 ppm Cd ) . - pubmed
[ Comparison of retinal breaks between patients with atopic dermatitis and mentally retarded patients with self - inflicted ocular injury ] . - pubmed
We compared the distribution of retinal breaks in retinal detachment between patients with atopic dermatitis ( AD ) and mentally retarded patients who had self - inflicted ocular injury ( MR ) . - pubmed
The cases of AD were 16 eyes in 14 patients ( six males and eight females , ranging in age from 15 to 52 years , mean 24.5 ) and the cases of MR were 6 eyes in 5 patients ( 5 males , ranging in age from 14 to 25 years , mean 20.2 ) . - pubmed
In the patients with AD , 14 ( 87.5 % ) of 16 eyes had retinal breaks at the vitreous base , and 21 ( 87.5 % ) of 24 retinal breaks in 16 eyes were at the vitreous base . - pubmed
In the patients with MR , five ( 83.3 % ) of 6 eyes had retinal breaks at the vitreous base and 6(66.7 % ) of 9 retinal breaks in 6 eyes were at the vitreous base . - pubmed
[ Effectiveness of mesoglycan therapy in patients with ischemia of the lower limbs . - pubmed
METHODS : In the present investigation we studied the effect of mesoglycan in patients with acute episodes of relative lower limb ischemia ( Stage IIb according to Leriche - Fontaine classification ) coming to our observation . - pubmed
RESULTS : From February 1995 thirty - six patients , 24 males and 12 females , aged between 45 and 83 years ( mean + /- SD : 69.8 + /- 7.5 ) coming to our observation for acute relative lower limb ischemia were enrolled . - pubmed
At baseline , the diagnosis was Fontaine 's IIb stage ( walking distance & lt ; or = 200 m ) in all patients , 17 patients presenting walking distance & lt ; 100 m. After 3 and 6 months of mesoglycan treatment a significant improvement of symptoms and signs was observed in all patients but one . - pubmed
The administration of mesoglycan was well tolerated , with only minor complaints in two patients ( one case of headache and one of diarrhea ) . - pubmed
CONCLUSIONS : The present preliminary results show that , in patients with acute episodes of relative lower limb ischemia , mesoglycan ( administered according to the described protocol ) is an effective and safe agent able to improve symptoms ( walking distance , pain , leg appearance ) and to possibly delay the need of surgical interventions . - pubmed
In the investigation 43 patients with type II diabetes mellitus and 33 normals were included . - pubmed
[ Seroprevalence of the infections caused by Borrelia Burgdorferi and Rickettsia Conorii in humans and dogs in primary health care of San Andreas del Rabanedo ( Leon , Spain ) ] . - pubmed
BACKGROUND : Positive results in infections of borrelia burgdorferi and Rickettsia conorii in human and canine population is studied in order to understand the situation of both in humans , and at the same time discover the importance of the dog as an indicator of these agents among those in the Health Area of San Andres del Rabanedo , Leon . - pubmed
RESULTS : Positivity in both infections was discovered in both humans and dogs . - pubmed
We describe a case of multiple lipoma of the tongue in a female patient aged 60 years who also presented subcutaneous cervical lipoma . - pubmed
Twenty out of the 29 patients already showed a normal resorption half a year after the determination of the resorption disorder , 5 patients after 1 year and 4 patients after 1 1/2 years . - pubmed
Eleven or 14 of the 29 patients , respectively , with pathologically decreased D - xylose resorption only had complaints of lower or upper gastrointestinal tract , respectively , and 10 patients did not have abdominal complaints at all . - pubmed
METHODS : We describe the case of a 76 - year - old woman who came under our observation due to stroke and atrial arrhythmia . - pubmed
METHODS : Four hundred and seventy - three patients with ankylosing spondylitis received placebo or active non - steroidal anti - inflammatory drug ( NSAID ) for 6 weeks , and changes between entry and completion were captured by BASDAI and the individual components . - pubmed
Two patients with pulmonary vein tachycardias demonstrating atypical P - wave morphology were investigated . - pubmed
One of the patients had a tachycardia with two different cycle lengths . - pubmed
P - wave morphology was evaluated in 12 - lead ECGs from two patients with incessant atrial tachycardia , during tachycardia and sinus rhythm . - pubmed
We hypothesize that dysfunction of homologous regions in the human infant could lead to impaired ability to respond to hypercapnia and could potentially be involved in the pathogenesis of SIDS . - pubmed
To investigate if these effects may be partly mediated by histamine release ( HR ) we studied the influence of SP on HR from nasal mucosa of subjects with and without allergic rhinitis using an in vitro organ culture system . - pubmed
SUBJECTS : Nasal mucosa of the inferior turbinate was obtained from ten patients suffering from allergic rhinitis and eighteen non - allergic subjects receiving surgical therapy for nasal obstruction . - pubmed
Visualization of rat pial microcirculation using the novel orthogonal polarized spectral ( OPS ) imaging after brain injury . - pubmed
Because receptors and cytokine ligands that mediate metastasis formation are sparsely expressed in the adult healthy organism and are more readily reached by pharmaceuticals than intracellular drug targets they may represent a particularly suitable focus for therapeutic intervention . - pubmed
OBJECTIVES : The purpose of the study was to assess the long - term outcome of patients with small ventricular septal defects ( VSDs ) considered not to require surgical closure during childhood . - pubmed
BACKGROUND : Although patients with small VSDs have generally been considered not to require surgery , more recent data suggest that a significant percentage of these patients develop serious problems during adult life . - pubmed
METHODS : A total of 229 consecutive patients ( 115 females ) with a VSD considered too small to require surgery during childhood as defined by normal pulmonary artery pressure , less than 50 % shunt , pulmonary vascular resistance & lt ; or = 200 dynes x s cm(-5 ) , no VSD - related aortic regurgitation ( AR ) , and no symptoms and who had no additional hemodynamically relevant heart defect were followed in an adult congenital heart disease program . - pubmed
For 118 patients who entered the study between 1993 and 1996 and were prospectively followed for 7.4 + /- 1.2 years , event - free survival with end points defined as death , endocarditis or heart surgery was 99.1 + /- 0.8 % at three years , 96.5 + /- 1.7 % at six years and 95.5 + /- 1.9 % at eight years . - pubmed
CONCLUSIONS : Outcome in well - selected patients with a small VSD is good . - pubmed
METHODS AND RESULTS : Thirteen patients developed myocardial ischemic injury within 2 weeks of cardiac transplantation ( ischemia group ) . - pubmed
These were compared with 10 transplantation patients who had no evidence of ischemia ( control group ) . - pubmed
One in four children affected by parental substance abuse . - pubmed
BACKGROUND : We have previously demonstrated in a rodent model the differential effects that specific intraluminal nutrients exert on gut ischemia / reperfusion ( I / R ) injury . - pubmed
Direct detection of enterovirus 71 ( EV71 ) in clinical specimens from a hand , foot , and mouth disease outbreak in Singapore by reverse transcription - PCR with universal enterovirus and EV71 - specific primers . - pubmed
BACKGROUND : Hazelnuts are a common cause of food allergy . - pubmed
Allergic reactions to hazelnuts range from oral allergy syndrome caused by cross - reactivity between tree pollen and hazelnut proteins to severe anaphylactic reactions . - pubmed
OBJECTIVE : The aim of the study was to identify these pollen - independent allergens in patients with hazelnut allergy with systemic reactions . - pubmed
Prevalence of sleep - disordered breathing and continuous positive airway pressure compliance : results in chinese patients with first - ever ischemic stroke . - pubmed
MEASUREMENTS AND RESULTS : We recruited 23 women and 28 men , who were admitted to the hospital within 4 days of stroke onset , with a mean ( + /- SD ) age of 64.2 + /- 13.0 years and a body mass index ( BMI ) of 24.3 + /- 4.4 kg / m(2 ) for this study . - pubmed
Twenty - seven patients ( 53 % ) and 9 patients ( 17.6 % ) , respectively , reported a history of snoring and severe daytime sleepiness prior to experiencing a stroke , while the mean Epworth sleepiness scale score was 6.8 + /- 3.6 . - pubmed
Polysomnography revealed 34 patients ( 67 % ) with an apnea - hypopnea index ( AHI ) of & gt ; or = 10 events per hour , 31 patients ( 61 % ) with an AHI of & gt ; or = 15 events per hour , and 25 patients ( 49 % ) with an AHI of & gt ; or = 20 events per hour . - pubmed
Significant obstructive SDB , defined as an AHI of & gt ; or = 20 / h , was more prevalent in ischemic stroke patients than in control subjects ( 49 % vs 24 % , respectively ; p = 0.04 ) and was associated with a higher BMI ( p = 0.046 ) . - pubmed
A subgroup of 20 patients not receiving CPAP showed partial spontaneous improvement of SDB at 1 month ( baseline AHI , 32.3 + /- 17.6 events per hour ; AHI at 1 month , 23.0 + /- 18.8 events per hour ; p = 0.01 ) with a trend toward improvement for the obstructive but no significant change for the central events , whereas no improvement in AHI was noted for the four patients receiving CPAP . - pubmed
Impact of non - axillary sentinel node biopsy on staging and treatment of breast cancer patients . - pubmed
A total of 549 breast cancer patients underwent lymphoscintigraphy after intratumoural injection of ( 99m ) Tc - nanocolloid . - pubmed
Internal mammary metastases were found in seventeen patients and metastases in other non - axillary sentinel nodes in ten patients . - pubmed
A small proportion of clinically node negative breast cancer patients can be staged more precisely by biopsy of sentinel nodes outside level I and II of the axilla , resulting in additional decision criteria for postoperative regional or systemic therapy . - pubmed
Hepatic arterial infusion using pirarubicin combined with systemic chemotherapy : a phase II study in patients with nonresectable liver metastases from colorectal cancer . - pubmed
PATIENTS AND METHODS : From December 1991 to April 1994 , 75 patients with unresectable colorectal metastases confined to the liver were included in this multicenter study to receive intra - arterial hepatic pirarubicin and a systemic monthly regimen of 5 - fluorouracil ( 5 - FU ) and folinic acid . - pubmed
RESULTS : Tolerance of this regimen was rather good ; however , functional catheter problems were observed in 29 patients ( 45 % ) resulting in failure of HAI in 21 cases ( 33 % ) after a median of three cycles ; vomiting grade 3 was present in 12.5 % of patients , neutropenia grade 4 in 23 % and alopecia grade 3 in 19 % . - pubmed
[ TREATMENT OF PATIENTS WITH RHEUMATOID ARTHRITIS WITH AN EXTRACT OF BETA - HEMOLYTIC STREPTOCOCCI ] . - pubmed
A total of 428 patients with insomnia aged 55 years and older received placebo ( 2 weeks ) , prolonged release melatonin 2 mg ( 3 weeks ) and then placebo ( 2 weeks ) . - pubmed
We present a case of an adult patient with truncus arteriosus communis and secondary pulmonary hypertension . - pubmed
Multidirectional voluntary glenohumeral dislocation in a 7 - year - old patient : a case report . - pubmed
SCN goitrogenic effects occur secondary to iodine deficiency in special circumstances of high consumption of incomplete detoxified cassava and insufficient protein intake . - pubmed
Potential applications include detection of coronary in - stent thrombosis or thrombus burden in patients with acute coronary syndromes . - pubmed
OBJECTIVE : To compare effectiveness of oral therapy with reduced nicotinamide adenine dinucleotide ( NADH ) to conventional modalities of treatment in patients with chronic fatigue syndrome ( CFS ) . - pubmed
METHODS : A total of 31 patients fulfilling the Centers for Disease Control criteria for CFS , were randomly assigned to either NADH or nutritional supplements and psychological therapy for 24 months . - pubmed
Chemotherapy alone vs. chemotherapy plus high dose multiple antioxidants in patients with advanced non small cell lung cancer . - pubmed
OBJECTIVE : To describe the unique nursing responsibilities involved in providing nursing care to severely obese weight loss surgery patients and to develop evidence - based guidelines for safe patient care . - pubmed
BACKGROUND : The uptake of omega-3 polyunsaturated fatty acids ( PUFAs ) into the liver , gut mucosa , and tumor tissue and plasma levels after preoperative administration of supplemented enteral nutrition was investigated in patients with malignancies of the upper gastrointestinal tract . - pubmed
CONCLUSIONS : This study suggests that administration of PUFA - enriched diets leads to increased incorporation of EPA and DHA not only in liver and gut mucosa tissue , but also in tumor tissue in patients with solid gastrointestinal tumors . - pubmed
Patient outcomes are improved when prolonged periods on dialysis and the complications of systemic oxalosis have not occurred . - pubmed
We evaluated the feasibility and efficacy of the emerging ' real - time three - dimensional transthoracic echocardiography ' technique for comprehensive assessment of cardiac anatomy , physiology , pathomorphology and pathophysiology in patients with structural heart disease . - pubmed
METHODS AND RESULTS : Patients with structural heart disease ( n=152 ) were evaluated by conventional two - dimensional transthoracic echocardiography and real - time three - dimensional transthoracic echocardiography using standard protocol . - pubmed
A total of 38 congenital heart disease patients were examined including 23 patients with atrial septal defect . - pubmed
To address this issue , appropriate animal models frequently clarify the etiology and pathogenesis of autoimmune diseases , although no single animal model perfectly mimics a human disease . - pubmed
Transgenic and knock out mice have advanced the investigation of cutaneous LE . - pubmed
Sevoflurane pretreatment inhibits endotoxin - induced shock in rats . - pubmed
Sequence analysis of full - length HBV genome showed more substitutions in X , rt , and surface proteins in patients with SHE than in those without elevated HBV DNA level . - pubmed
We undertook a retrospective chart review during a 24 - month period of patients treated at an outpatient burn center . - pubmed
The medical records of patients with neuropathic - like pain complaints , including the sensation of pins and needles , burning , stabbing , shooting , or " electric " sensations , were included for analysis . - pubmed
Predictors for complications after loop stoma closure in patients with rectal cancer . - pubmed
PURPOSE : This unmatched case control study was undertaken to evaluate factors contributing to surgery - related complications of loop stoma closure in patients with rectal cancer . - pubmed
CONCLUSIONS : The present study in a homogeneous group of patients with rectal cancer as elective indication for temporary loop stoma construction confirms the high complications rate and mortality rate associated with stoma closure . - pubmed
RESULTS : Peripheral blood eosinophilia was observed in the ' ig ' and ' ig / in'-NRL - sensitized animals in comparison to normal controls ( p & lt ; 0.05 ) . - pubmed
Increased airway hyperreactivity was found in ' ig'-NRL - sensitized - mice ( 15.1 + /- 2.5 vs. 8.9 + /- 1.7 cm H2O x ml(-1 ) x s , p & lt ; 0.05 ) . - pubmed
CONCLUSION : The option of LPV / r monotherapy as maintenance therapy in HIV - infected patients following induction of virological response with triple therapy including LPV / r might be a more efficient alternative than maintaining triple therapy , as evidenced by a more favorable cost - efficacy ratio . - pubmed
Four months after the treatment the patient presented no symptoms and GP did not recur . - pubmed
PURPOSE : Axonal damage and loss of neurons correlate with permanent vision loss and neurologic disability in patients with optic neuritis and multiple sclerosis ( MS ) . - pubmed
METHODS : Experimental autoimmune encephalomyelitis ( EAE ) , an animal model of MS , was induced by immunization with proteolipid protein peptide in SJL / J mice . - pubmed
OBJECTIVE : In this work , we analyzed the vertical transmission of dengue virus in Aedes aegypti mosquitoes collected in two endemic localities in the state of Oaxaca , Mexico . - pubmed
Additional studies are needed to clarify the relationship between the two epidemics so that effective interventions can be developed to improve the health and lives of children with both asthma and obesity . - pubmed
Acute lupus pneumonitis in an 11 - year - old girl with lupus nephritis is reported . - pubmed
METHODS : In this cross - sectional case - control study 313 unrelated Caucasians ( Slovene population ) with type 2 diabetes mellitus were enrolled : 206 patients with PDR and the control group of 107 subjects with type 2 diabetes of duration of more than 10 years who had no clinical signs of diabetic retinopathy . - pubmed
A 64 - year - old woman with intermittent vaginal bleeding was referred under the clinical impression of cervical cancer . - pubmed
The prognosis of patients with pericardial and abdominal wall metastases from recurrent cervical cancer is usually poor because of the systemic dissemination of the disease . - pubmed
PATIENTS : Forty - one adult patients diagnosed with otitis media with effusion were recruited into the trial and underwent grommet insertion under local anesthesia ; 21 were randomly allocated to the EMLA group and 20 to the Ametop group . - pubmed
MAIN OUTCOME MEASURES : The primary outcome measure of the study was the level of pain experienced by the patient . - pubmed
[ The formation of infliximab and anti - infliximab immune complexes as an explanation for non - responding to infliximab treatment of rheumatoid arthritis : observational study in 4 patients ] . - pubmed
OBJECTIVE : To investigate the in vivo mechanism of non - responding to infliximab treatment of patients with rheumatoid arthritis ( RA ) and the role of anti - infliximab antibodies by using radiolabeled infliximab . - pubmed
METHOD : Two responding and two non - responding RA patients were infused with radiolabeled infliximab . - pubmed
Biomechanical testing was performed on pig thoracic spines instrumented with 7 - segment anterior scoliosis constructs . - pubmed
We report a patient with cervical nerve root compression operated by anterior transdiscal approach with plate and bone graft . - pubmed
Helium breathing provides modest antiinflammatory , but no endothelial protection against ischemia - reperfusion injury in humans in vivo . - pubmed
We hypothesized that inhalation of helium provides protection against postocclusive endothelial dysfunction after ischemia - reperfusion of the forearm in humans . - pubmed
Each volunteer was randomly exposed to 15 min of forearm ischemia in the presence or absence of helium inhalation . - pubmed
The tests allowed to determine the boundary values of the growth inhibition zones and the minimum inhibitory concentrations of the antibiotics for susceptible and resistant strains of B. - pubmed
Nutrient media and reference strains for testing antibiotic susceptibility of B. - pubmed
METHODS : Records of 19 men and 11 women aged 9 to 34 ( mean , 17 ) years with osteosarcoma around the knee joint were reviewed . - pubmed
RESULTS : In all patients , the first symptom was pain , which was more pronounced on weight bearing in 16 ( 53 % ) of them and was worse at night in 11 ( 37 % ) . - pubmed
Swelling was noticed in 28 patients ( a mean of 7 weeks after pain onset ) . - pubmed
The mean interval from presentation to radiography was 3 ( range , 0 - 20 ) weeks ; in 8 patients this interval exceeded 3 weeks despite a noticeable swelling . - pubmed
There has been a recent focus on the presence of nerve fibers in the eutopic endometrium of patients with endometriosis . - pubmed
STUDY DESIGN : Cross - sectional study of computed tomographic scans of the temporal bones in patients with no congenital abnormalities . - pubmed
SUMMARY A fast - neutron mutagenized population of rice seedlings was screened with Magnaporthe grisea , the causal agent of rice blast disease , to identify mutants with alterations in the defence response . - pubmed
The fourth mutant line , ncr1 ( necrosis in rice ) , has an LM phenotype under all conditions tested and lacks enhanced resistance to either M. - pubmed
It has been shown previously that treating an animal with N - acetyl - L - cysteine ( NAC ) , a scavenger of free radicals , significantly minimizes hypoxic - ischemic - induced brain injury in various acute models . - pubmed
Using a subacute swine model of neonatal hypoxia - reoxygenation ( H - R ) , we evaluated the long - term beneficial effect of NAC against oxidative stress - induced brain injury . - pubmed
Serotonin syndrome in an orthopaedic patient secondary to linezolid therapy for MRSA infection . - pubmed
A 67 - year - old patient was admitted for incision and drainage of a recurrent methicillin - resistant Staphylococcus aureus ( MRSA ) hip abscess . - pubmed
Between 2004 and 2009 , 60 patients with proximal tibial fractures were included in this prospective study . - pubmed
There was one case of lateral joint collapse ( & gt;10 ) in a patient with open bicondylar plateau fracture . - pubmed
RATIONALE : Mortality is exceedingly high and rapid among patients infected with HIV and tuberculosis ( TB ) , in part because of limited access to appropriate TB diagnostics . - pubmed
The microscopic observation drug - susceptibility ( MODS ) assay is a simple , rapid , low - cost test for TB and multidrug - resistant ( MDR ) TB , but data in individuals infected with HIV and in Africa are limited . - pubmed
MODS test performance did not differ by patients ' HIV status ( sensitivity 88 % vs. 90 % , specificity 97 % vs. 100 % for HIV - positive versus HIV - negative , respectively ) . - pubmed
CONCLUSIONS : Among adult TB suspects predominantly infected with HIV , MODS provided high sensitivity and specificity for rapid diagnosis of TB and MDR - TB . - pubmed
It is also a testicular germ cell tumor susceptibility factor in mice . - pubmed
Normalized coagulation markers and anticoagulation proteins in children with severe beta - thalassemia disease after stem cell transplantation . - pubmed
The hypercoagulable state is well recognized in patients with severe beta - thalassemia disease . - pubmed
METHODS : Data were obtained retrospectively from patients with massive suprachoroidal hemorrhage who were treated in Worthing and Southlands National Health Service Trust between January 2003 and December 2008 . - pubmed
All patients underwent early controlled drainage of massive suprachoroidal hemorrhage using 100 % perfluoropropane as a tamponade . - pubmed
The remaining three patients had poor visual outcome because of retinal detachment with proliferative vitreoretinopathy . - pubmed
The most common risk factor in this case series was glaucoma , which was seen in five patients . - pubmed
Arteriosclerosis was the only risk factor in two patients . - pubmed
For patients admitted to medical units , optimal management of delirium includes reassessment of medications , pain , sleep , nutrition , mobility , need for physical restraints , and bowel and bladder function . - pubmed
Multicomponent interventions performed by the hospital care team that address risk factors can prevent delirium in patients in medical units and those undergoing hip fracture repair . - pubmed
This includes attention to the depth of sedation during spinal anesthesia and the addition of regional nerve blocks to patient - controlled analgesia in orthopedic patients , both of which may reduce postoperative delirium . - pubmed
METHODS AND FINDINGS : 95 patients were included , and they were divided into three groups with different burn area : group I ( n = 33 ) , group II ( n = 32 ) and group III ( n = 30 ) . - pubmed
According to whether there was development of MODS or not , patients were divided into MODS group ( n = 28 ) and none - MODS group ( n = 67 ) ; then the patients with MODS were further divided into non - survivor group ( n = 17 ) and survivor group ( n = 11 ) . - pubmed
The similar results were found in MODS patients and the non - survivor group as compared with those without MODS and the survival group on days 3 - 21 postburn ( P<0.05 or P<0.01 ) . - pubmed
RESULT : The primary features of these patients were prolonged high - grade fever ( 50/50 ) , hepatomegaly ( 44/50 ) , splenomegaly ( 38/50 ) , hemocytopenia ( 47/50 ) , hyperferritinemia ( 49/50 ) , coagulopathy ( 44/50 ) , hemophagocytosis in bone marrow ( 42/50 ) , liver dysfunction ( 42/50 ) and hypertriglyceridemia ( 42/50 ) . - pubmed
Newcastle disease virus : a promising agent for tumour immunotherapy . - pubmed
Malignant tumours are a major cause of mortality in humans . - pubmed
Currently used therapeutic regimens have not improved survival rates of patients suffering from malignant tumours much because of their limited efficacy and side - effects . - pubmed
A therapeutic approach that uses Newcastle disease virus ( NDV ) represents an attractive new tool for tumour immunotherapy . - pubmed
Significant evidence exists regarding the oncolytic effects of NDV , suggesting its potential use in the treatment of various tumours . - pubmed
Furthermore , clinical trials have suggested that several NDV strains have the potential for cancer virotherapy with few side - effects compared with traditional treatments . - pubmed
Apoptosis following NDV infection may contribute to the observed oncolytic effects ; however , NDV could also stimulate both innate and adaptive antitumour immune responses . - pubmed
For many years , different approaches have been investigated ( or are in the process of being developed ) regarding the use of NDV for the treatment of malignancies . - pubmed
Recent advances using reverse genetics have provided a means of generating recombinant NDV strains with improved oncolytic and immune regulatory properties . - pubmed
CONCLUSIONS / SIGNIFICANCE : The human vaginal bacterial biota is heterogeneous and marked by greater species richness and diversity in women with BV ; no species is universally present . - pubmed
The incidence of this disorder is probably less than 1 % in patients with mild hypertension , but rises to as high as 10 to 40 % in patients with acute , severe or refractory hypertension . - pubmed
Atherosclerotic lesions are present in almost 7 % of adults older than 65 years and up to 50 % of patients presenting with diffuse atherosclerotic disease . - pubmed
Pharmacological therapy in patients diagnosed with Peyronie ' s disease . - pubmed
The combination between oral therapy and intralesional agents can improve the quality of life of the patients with Peyronie ' s disease . - pubmed
We present two cases of self - inflicted urethrovesical foreign body in children . - pubmed
Foreign bodies are rarely found in the lower urinary tract of children . - pubmed
INTRODUCTION : The aim of this study was to investigate the intraoperative findings , postoperative complications , donor site morbidity and patients ' Quality of Life in order to evaluate the usefulness of the free osteofasciocutaneous fibula flap in the reconstruction or construction of a mandibula , neophallus , lower leg or forearm . - pubmed
The larger size of this rat model as compared with the ALS mice , will facilitate studies involving manipulations of spinal fluid and the spinal cord . - pubmed
The effectiveness of ridetherapy in children with benign joint hypermobility syndrome during articulatory changes in the knee joint . - pubmed
It has been established that in children with benign joint hypermobility syndrome during articulatory changes in the knee the use of ridetherapy provides an increase in muscle strength , to a certain degree their hypertrophy , the development of joint - muscular perception , the increase of proprioreception , the minimizing of excessive joint movement , the antinociceptive effect and the avoidance of secondary developed complications . - pubmed
The identified strain SHSY of S. - pubmed
Paclitaxel is a widely used chemotherapy drug for advanced laryngeal cancer patients . - pubmed
However , the fact that there are 20 - 40 % of advanced laryngeal cancer patients do not response to paclitaxel makes it necessary to figure out potential biomarkers for paclitaxel sensitivity prediction . - pubmed
Collectively , our study might provide potential biomarkers for paclitaxel sensitivity prediction and drug resistance targets in laryngeal cancer patients . - pubmed
Use of ticagrelor in patients with ST - elevation myocardial infarction undergoing thrombolysis . - pubmed
PURPOSE : The aim of the present study was to test the hypotheses that a greater oxidative capacity in children results in a lower phosphocreatine ( PCr ) depletion , a faster PCr resynthesis and a lower muscle acidification during high - intensity intermittent exercise compared to adults . - pubmed
CONCLUSIONS : From our results we suggest relatively higher rates of oxidative ATP formation in children 's muscle for covering the ATP demand of high - intensity intermittent exercise compared to adults , enabling children to begin each exercise interval with significantly higher PCr concentrations and leading to an overall lower muscle acidification . - pubmed
Split cord malformation types I and II : a personal series of 131 patients . - pubmed
PURPOSE : A personal series of 131 patients with split cord malformation ( SCM ) operated on is presented . - pubmed
The ages of patients with neurological deficits and orthopedic deformities were significantly older than those without deficits ( P = 0.030 ) . - pubmed
The duration of symptoms was longer in the patients with neurological deficits and orthopedic deformities than that in those without deficits ( P = 0.00095 ) . - pubmed
In six patients , composite SCMs were present . - pubmed
Only one patient with a type II SCM did not have an associated spinal cord lesion . - pubmed
A type I SCM was more frequently encountered in patients with spina bifida ( P & lt ; 0.0005 ) . - pubmed
Transient postoperative complications were seen in 29 patients ( 22 % ) . - pubmed
Retethered cord syndrome developed in five patients with a type I SCM . - pubmed
CONCLUSIONS : The risk of neurological and orthopedic deficits increases with the age of the patient . - pubmed
All patients should be surgically treated when diagnosed , especially before the development of orthopedic and neurological manifestations , and all associated lesions should also be treated at the same session . - pubmed
Aflp analysis of xanthomonas axonopodis and x. Arboricola strains used in xanthan production studies reveal high levels of polymorphism . - pubmed
Amplified fragment length polymorphism ( AFLP ) was used to analyze the genetic diversity of 14 strains of Xanthomonas arboricola pv . - pubmed
pruni and seven strains of X. - pubmed
All 14 pathovar pruni strains were included in a single main group ( SD = 0.58 ) , while the pathovar phaseoli strains were divided into three separate groups , with one group containing five strains ( SD = 0.38 ) and two isolated groups ( SD = 0.31 and 0.27 ) composed of only one strain each . - pubmed
For the unique strain without xanthan production capacity ( X. - pubmed
In two patients , satisfaction was low due to residual loss of flexion as a result of osteoarthritis and cold intolerance in another . - pubmed
Altered pharmacokinetics of piperacillin in febrile neutropenic patients with hematological malignancy . - pubmed
This study assessed the pharmacokinetics and dosing adequacy of piperacillin in febrile neutropenic patients after the first dose . - pubmed
Chemotherapy research highly prioritizes overcoming the multidrug resistance ( MDR ) in human tumors . - pubmed
MATERIALS AND METHODS : In this case - control study , 20 infertile POR patients and 20 normal women took part in this study and underwent controlled ovarian stimulation . - pubmed
This review summarizes recent key findings on human and mouse monocyte subpopulations , specifically highlighting their phenotype , functional characteristics and mechanisms of recruitment at homeostatic conditions , in atherosclerotic vascular disease , and after acute myocardial infarction . - pubmed
OBJECTIVE : To present our experience regarding transumbilical single - incision laparoscopic heminephroureterectomy ( SILH ) in children with duplex kidney anomalies , and to investigate its feasibility and safety compared with those of conventional laparoscopic heminephroureterectomy ( CLH ) . - pubmed
PURPOSE : To review bicycle and motorcycle wheel spoke injuries around the foot and ankle in 24 children . - pubmed
METHODS : Medical records of 12 boys and 12 girls aged 2 to 11 ( mean , 5.3 ) years who presented with an isolated posterior heel injury caused by wheel spokes of a motorcycle ( n=9 ) or bicycle ( n=15 ) were reviewed . - pubmed
RESULTS : All 9 motorcycle injury patients and 8 of 15 bicycle injury patients had lacerations . - pubmed
The remaining 7 bicycle injury patients had abrasions and developed skin necrosis and ulcerations , with 5 requiring debridement . - pubmed
Seven patients with severe skin loss required skin grafting or flap surgery for wound coverage . - pubmed
Studies in human SK - N - SH neuroblastoma cells revealed that CM572 induced an immediate dose - dependent increase in cytosolic calcium concentration . - pubmed
The cytotoxic activity of CM572 was selective for cancer cells over normal cells , being much less potent against primary human melanocytes and human mammary epithelial cells . - pubmed
Mechanisms of acute toxicity are likely conserved across invertebrate , aquatic , and mammalian species , suggesting that dose - response concordance would be high and in vitro mechanistic data could predict responses in multiple species under conditions of similar bioavailability . - pubmed
We tested this hypothesis by comparing acute toxicity between rat , daphnia , and fish and by comparing their respective acute data to inhibition of mitochondria membrane potential ( MMP ) using U.S. Environmental Protection Agency ToxCast in vitro high - throughput screening data . - pubmed
Logarithmic scatter plots of acute toxicity data showed a clear relationship between fish , daphnia , and intravenous rat but not oral rat data . - pubmed
No samples from the patients with secondary MN and other glomerulonephritis or healthy controls were positive with the ELISA test . - pubmed
Adult patients undergoing gross total resection of intracranial atypical meningioma are eligible . - pubmed
Patients with multiple meningioma , optic nerve sheath meningioma , previous intracranial tumour , previous cranial radiotherapy and neurofibromatosis will be excluded . - pubmed
METHODS : Nineteen adolescents on average 7.5 months post - mTBI completed neuropsychological testing and an fMRI auditory - verbal N - back working memory task . - pubmed
The comparison group included 19 healthy controls matched to the mTBI group for demographic variables and N - back task performance . - pubmed
Effects of Interscalene Nerve Block for Postoperative Pain Management in Patients after Shoulder Surgery . - pubmed
Patients ' characteristics , preoperative shoulder score and range of motion , surgical and anesthetic condition in addition to visual analog scale ( VAS ) pain score , postoperative PCA consumption , and adverse outcomes were evaluated . - pubmed
In this study , we report a biological screening of 38 chemically characterized terpenes from different classes , which have a hydroxyl group connected by hydrophobic chain or an acceptor site , against the blood fluke Schistosoma mansoni , the parasite responsible for schistosomiasis mansoni . - pubmed
Confocal laser scanning microscopy revealed that compound 10 induced severe tegumental damage in adult schistosomes and a correlation between viability and tegumental changes was observed . - pubmed
Loss of T Follicular Helper Cells in the Peripheral Blood of Patients with Chronic Graft - versus - Host Disease . - pubmed
In contrast to mouse models , where an enhanced frequency of splenic TFH cells contributes to cGVHD , patients with cGVHD showed significantly depleted circulating TFH cells after both UCB and MRD transplantation . - pubmed
METHODS : A retrospective analysis of a prospectively entered database was performed for all patients who underwent lung cancer resection from January 2012 to June 2014 . - pubmed
RESULTS : Of 315 patients with primary lung cancer , 55.6 % were female and the mean age was 70 + - 9.6 years . - pubmed
Preoperative brain MRI detected asymptomatic metastases in four of 315 patients ( 1.3 % ) . - pubmed
At a median postoperative follow - up of 19 months ( range 6 - 43 ) , symptomatic brain metastases developed in seven additional patients . - pubmed
The objectives of this study were to determine the effect of the dry cow management system ( pasture or confined ) on : ( 1 ) lying behaviour and activity ; ( 2 ) feeding and heat stress behaviours ; ( 3 ) intramammary infections , postpartum . - pubmed
BACKGROUND : Testicular cancer is one of the most common and most treatable cancers in men aged 15 - 49 years . - pubmed
AIMS : This article aims to offer a complete and concise overview of cognitive dysfunction and quality of life for patients with testicular cancer . - pubmed
Immune responses to polyclonal T - cell vaccination in patients with progressive multiple sclerosis . - pubmed
To explore this , in this study , 39 patients with progressive ( chronic ) multiple sclerosis ( MS ) were multiply immunized with autological polyclonal T - cell vaccines ( TCVs ) . - pubmed
T - Cell vaccination had no significant effects on T - cell sub - population contents in the blood of MS patients after 2 years of immunotherapy initiation . - pubmed
Collectively , the results suggest that polyclonal T - cell vaccination is safe to use , able to induce measurable , long - lasting , anti - inflammatory immune effects in patients with advanced MS . - pubmed
We present the complete and annotated genome sequence of strain Szeged of PCV1 , determined by Pacific Biosciences RSII long - read sequencing platform . - pubmed
The objective of this study was to evaluate the utility of exercise testing in asymptomatic patients with type 1 Brugada pattern to prognosticate major arrhythmic events ( MAE ) during follow - up . - pubmed
METHODS AND RESULTS : Treadmill exercise testing was conducted for 75 asymptomatic patients with type 1 Brugada pattern and for 88 healthy control subjects . - pubmed
KEY RESULTS : 56 EGJOO , 40 HE patients and 33 controls were identified . - pubmed
Platelet counts had a nadir at day 3 followed by a rebound thrombocytosis at day 21 , with nadir values significantly lower in septic patients . - pubmed
METHODS : Tissue samples were collected from 136 patients with ocular venous malformation . - pubmed
A total of 124 patients had no complication up to 2 years after LDLT , and 74 patients had complications including biliary stricture and graft rejection . - pubmed
Adjuvant therapy is rarely used because there is no evidence to distinguish patients with high recurrence risk . - pubmed
The median follow - up was 71months ( range : 12months-143months ) , 129 patients ( 25.5 % ) experienced recurrence with median disease - free survival ( mDFS ) of 19months . - pubmed
Lung lobe torsion in seven juvenile dogs . - pubmed
CASE DESCRIPTION 7 juvenile ( & lt ; 12 months old ) dogs with lung lobe torsion were evaluated . - pubmed
A CBC showed leukocytosis and neutrophilia in all dogs . - pubmed
Anemia was present in 6 dogs , 2 of which received packed RBC transfusions . - pubmed
Clinicians should be aware of the possibility of lung lobe torsion when evaluating young dogs with clinical signs related to the respiratory system , including those with vague signs , to avoid undue delays in treatment . - pubmed
A 73 - year - old man presented with three episodes of dysphasia and disinhibited behaviour , a single seizure and transient ischaemic attack - like events characterised by right arm and/or leg weakness . - pubmed
Repeated cerebrospinal fluid examination showed a persistent lymphocytosis with mildly reduced glucose and elevated protein ; oligoclonal bands and viral PCR were negative . - pubmed
The leading cause of hyponatremia in patients with cancer is syndrome of inappropriate antidiuretic hormone secretion ( SIADH ) ; this oncologic emergency requires immediate intervention . - pubmed
Out of 110 patients , 13 patients ( 11.8 % ) required colectomy for technical failure ( 7 patients ) or carcinoma ( 6 patients ) . - pubmed
During a median follow - up of 16 months ( range 6 - 41 months ) , 2 patients had adenoma recurrence . - pubmed
CONCLUSIONS : Advanced endoscopic surgery appears to be a safe and effective alternative to colectomy for patients with complex premalignant lesions deemed unresectable with conventional endoscopic techniques . - pubmed
A 35 - year - old woman presented with a three - month history of left groin and thigh pain . - pubmed
Case presentation : We report the case of a patient with full thickness burns on both legs , leading to the exposure of joints of the right ankle and the right foot and left patellar tendon . - pubmed
We used C57BL / 6 mice infected by Plasmodium berghei ANKA ( PbA - infected mice ) , a well - known murine model of severe malaria . - pubmed
Proteolysis in septic shock patients : plasma peptidomic patterns are associated with mortality . - pubmed
We investigated in humans the relationship between septic shock , proteolysis , and outcome . - pubmed
METHODS : Intensive care patients with septic shock ( n=29 ) or sepsis ( n=6 ) and non - hospitalised subjects ( n=9 ) were recruited as part of the prospective observational trial ' ShockOmics ' ( ClinicalTrials.gov Identifier NCT02141607 ) . - pubmed
RESULTS : Evidence of systemic proteolysis was indicated by a larger number of circulating peptides in septic shock patients , compared with septic patients and non - hospitalised healthy subjects . - pubmed
The peptide count and abundance in the septic shock patients were greater in patients who died ( n=6 ) than in survivors ( n=23 ) , suggesting an association between magnitude of proteolysis and outcome . - pubmed
Plasma peptidomics is proposed as a new tool to monitor clinical trajectory in septic shock patients . - pubmed
BACKGROUND : Limited data are available regarding the characteristics and prognosis of patients with stroke due to varicella zoster virus ( VZV ) vasculopathy . - pubmed
METHODS : We studied 4 patients ( 2 men and 2 women ; age , 38 - 63 years ) from a single center who developed acute ischemic stroke due to VZV vasculopathy . - pubmed
Each patient had a characteristic skin rash prior to stroke , with the interval from rash to stroke onset ranging from 13 to 122 days . - pubmed
Two patients experienced antecedent cranial nerve palsies ; one had the third , seventh , ninth , and 10th nerve palsies and the other had the fourth nerve palsy before stroke . - pubmed
Intracranial arterial stenosis was only identified in one patient on magnetic resonance angiography . - pubmed
As a result of combined therapies with acyclovir , steroid , and antithrombotic agents , neurological symptoms markedly improved in 3 patients , whereas 1 patient was left with moderate hemiplegia . - pubmed
CONCLUSIONS : Cranial nerve palsies may be prodromal symptoms of VZV - associated stroke . - pubmed
METHODS : Three hundred nine postmenopausal female patients with osteoporotic vertebral compression fractures were included in the study . - pubmed
Recurrent infections with this bacterium are common , suggesting that S. - pubmed
Using an ex vivo infection model of primary human monocyte - derived dendritic cells , we found that S. - pubmed
Although all purified leukocidins could kill DCs , infections with live bacteria revealed that S. - pubmed
Herein , we describe the successful management of a patient with an otherwise inoperable , ruptured aortic root pseudoaneurysm using combined cardioaortic replacement under hypothermic circulatory arrest . - pubmed
A blend of dietary lovastatin and delta - tocotrienol , each at no - effect doses , suppress the growth of implanted murine B16 melanomas in C57BL6 mice . - pubmed
Effects of electroacupuncture on anxiety and depression in unmarried patients with polycystic ovarian syndrome : secondary analysis of a pilot randomised controlled trial . - pubmed
OBJECTIVE : To evaluate the efficacy of electroacupuncture ( EA ) for the treatment of anxiety and depression in unmarried patients with polycystic ovarian syndrome ( PCOS ) by secondary analysis of a randomised controlled trial . - pubmed
METHODS : A prospective pilot randomised controlled trial of unmarried women with PCOS was conducted from November 2012 to March 2016 . - pubmed
CONCLUSION : EA appears to improve symptoms of anxiety / depression and quality of life in PCOS patients and may influence serum levels of NE and 5 - HT . - pubmed
Zone Formation of Lymphocyte Infiltration at the Invasive Front Results in the Prolonged Survival of Individuals With Endometrial Serous Carcinoma and Endometrioid Carcinoma With Serous Component . - pubmed
RESULTS : Out of a total of 51 patients , 38 cases had weak LI and 13 had strong LI . - pubmed
The progression - free survival of patients with weak LI was worse ( p=0.02 ) . - pubmed
To demonstrate the feasibility of robotic middle ear access in a clinical setting , nine adult patients with severe - to - profound hearing loss indicated for cochlear implantation were included in this clinical trial . - pubmed
Erratum : Cumulative radiation exposure from imaging procedures and associated lifetime cancer risk for patients with lymphoma . - pubmed
Finally , subcutaneous xenotransplanted tumor models of HCT116 cells were established in BALB / c nude mice . - pubmed
Since insufficient sources of transplantable liver and possible immune rejection severely hinder the wide application of conventional liver transplantation therapy , artificial three - dimensional ( 3D ) liver culture and assembly from stem cells have become a new hope for patients with end - stage liver diseases , such as cirrhosis and liver cancer . - pubmed
Long - term remissions of young patients with high - risk follicular lymphoma after first - line autologous stem cell transplantation : Three case reports . - pubmed
PATIENT CONCERNS : 3 young - adult patients with FL received ASCT as first - line treatment . - pubmed
DIAGNOSIS : All the 3 patients were no more than 30 years old and the diagnosis of FL was confirmed by histopathological and immunohistochemical evaluations . - pubmed
OUTCOMES : All the 3 patients got complete remission and minimal residual disease negativity after ASCT , The median follow - up time was 109 ( 97 - 117 ) months , and all of them were in remission more than 8 years after transplant . - pubmed
LESSONS : Guidelines for FL are mainly based on elderly patients , but are not suitable enough for all , especially for the young FL patients . - pubmed
Nowadays , the pathogenesis of minimal change disease ( MCD ) is still not well - known , and the current understanding on MCD is mainly based on data derived from children , and very few adults . - pubmed
The results showed that in patients at the onset of MCD , the ratio and activation of basophils were all higher than those of healthy controls ( all P < .05 ) . - pubmed
In vitro test results showed that basophils from healthy controls can be activated by the serum taken from patients with MCD . - pubmed
Among 62 patients at the onset of MCD , with complete remission after treatment and 1 year of follow - up , the relative and absolute basophil counts before treatment were higher in the long - term remission group ( n = 33 ) than that of the relapse group ( n = 29 ) . - pubmed
Hyperoxia in patients with cardiogenic shock after myocardial infarction supported with venoarterial extracorporeal membrane oxygenation . - pubmed
BACKGROUND : Venoarterial extracorporeal membrane oxygenation ( V - A ECMO ) improves perfusion and oxygenation in patients with cardiogenic shock . - pubmed
Recent evidence suggests hyperoxia may be harmful , particularly in critically ill patients . - pubmed
The aim of this study was to describe oxygen exposure in patients receiving V - A ECMO after acute myocardial infarction and to investigate the association between hyperoxia and in - hospital mortality . - pubmed
We compared the mean and peak arterial oxygen tensions over the first 72 h after V - A ECMO initiation ( n = 30 ) with those from a convenience sample of patients treated with an intra - aortic balloon pump ( IABP ) ( n = 30 ) for cardiogenic shock . - pubmed
Patients on V - A ECMO had significantly higher arterial oxygen tensions during the first three days than those with an IABP , at 0 - 24 h ; V - A ECMO : 286.51 mmHg ( 135.76 ) vs IABP : 103.48 mmHg ( 15.22 ) , p < 0.01.Thirteen of 30 ( 44.8 % ) patients in the V - A ECMO cohort manifested extreme hyperoxia ( PaO2 > = 300 mmHg ) in the first 24 hrs , compared with none in the IABP population . - pubmed
CONCLUSION : Severe hyperoxia is common in patients receiving V - A ECMO after acute myocardial infarction , and this continues for at least 72 h. We found no association between extreme hyperoxia and clinical outcomes . - pubmed
Return to driving is a better predictor of patient outcome than return to work after aneurysmal subarachnoid hemorrhage . - pubmed
OBJECTIVE : Return to work and driving are major rehabilitation goals for patients after an aneurysmal subarachnoid hemorrhage ( aSAH ) . - pubmed
METHODS : Medical records of patients with aSAH were retrospectively reviewed from 2010 - 2018 . - pubmed
Septicaemia of subterranean termites Coptotermes curvignathus caused by disturbance of bacteria isolated from termite gut and its foraging pathways . - pubmed
METHODS : Mothers ( N = 181 ) were assessed periodically , beginning at 16 weeks ' gestation , using the Center for Epidemiologic Studies - Depression Scale . - pubmed
CONCLUSIONS : Although the expansion of the North American Contact Dermatitis Group standard screening series has decreased the yield from the AVC series from 21.1 % to 13.9 % , it still remains a useful adjunct for patients suspected of having cosmetics or disinfectants allergy . - pubmed
BACKGROUND : This retrospective study was conducted to know clinical and radiographic outcomes , complication rate , and survival of THA in patients with high hip dislocation secondary to developmental dysplasia(DDH ) or septic arthritis of the hip(SSH ) . - pubmed
METHODS : Between March 2005 and September 2014 , there were consecutive series of 53 THAs in patients with a highly dislocated hip secondary to DDH or SSH . - pubmed
Two patients developed proximal humerus fractures , of which 1 had osseous changes through which the fracture occurred . - pubmed
Our findings show these AAV - XV variants are highly efficient at cell transduction at low dose and demonstrates the importance of the AAP coding region in both viral particle assembly and cell infection . - pubmed
By virtue of neutralizing antibodies against AAV that impede patient repeat - dosing , the dose of AAV for in vivo gene delivery has been high , which has resulted in unfortunate recent safety concerns and deaths in patients given higher - dose AAV gene therapy . - pubmed
Impact of statin on long - term outcome among patients with end - stage renal disease with acute myocardial infarction ( AMI ): a nationwide case - control study . - pubmed
However , in patients with end - stage renal disease ( ESRD ) , the protective effects of statin are controversial . - pubmed
To evaluate the impact of chronic statin use on clinical outcomes of patients with acute myocardial infarction ( AMI ) with ESRD . - pubmed
We compared the effects of statin use in term of all - cause death among patients with AMI with ESRD . - pubmed
RESULTS : Statin use resulted in a significantly higher survival rate in patients ith AMI with ESRD compared with non - statin users . - pubmed
After adjusted the comorbidities the male patients and patients with DM , PVD , HF and CVA had lower long - term survival rate ( all p<0.001 ) . - pubmed
Patients with AMI with ESRD on statin therapy exhibited a significantly lower risk of mortality compared with non - statin users ( p<0.0001 ) . - pubmed
CONCLUSION : Among patients with ESRD with AMI , statin therapy was associated with reduced all - cause mortality . - pubmed
Though most patients with renal involvement linked to antineutrophil cytoplasmic antibodies associated vasculitis ( AAV ) have pauci - immune glomerulonephritis , only a few patients were identified to have atypical renal pathology . - pubmed
Echothiophate cataracts in monkeys . - pubmed
coli UTI than screening for antibodies against the selected uropathogenic E. - pubmed
The pharmacokinetic disposition of prednisolone was studied following oral administration ( 10 mg ) to eight patients with untreated coeliac disease of mild or moderate severity , seven coeliac patients on a strict gluten - free diet and ten normal subjects . - pubmed
A representative sample of 95 hospitalized bipolar manic - depressive patients was followed up from 1959 to 1975 . - pubmed
In 525 operations on the heart and major vessels neurologic complications were noted in 47 patients . - pubmed
Lordosis behaviour in male , female and androgenized female rats . - pubmed
The transfer of deuterium from [ 1 R-2H ] ethanol and [ 1 S-2H ]- ethanol to reduced metabolites of administered compounds was measured in female rats provided with bile fistulas . - pubmed
Aldosterone and corticosterone production in renal hypertensive rats . - pubmed
The development of hypertension , which had been elicited by clamping one renal artery in the presence of an untouched contralateral kidney , has been pursued in rats for up to six weeks after operation , and aldosterone and corticosterone production was studied at various intervals . - pubmed
Ovulation induction with a single - blind treatment regimen comparing naltrexone , placebo and clomiphene citrate in women with secondary amenorrhea . - pubmed
A single - blind ovulation induction protocol comparing naltrexone , placebo and clomiphene citrate was evaluated in eight patients with secondary amenorrhea . - pubmed
Extension of these findings to disease - related immunogens may yield effective antigen - specific treatments of human allergy and autoimmune diseases . - pubmed
Polyvalent antibodies to S typhi were demonstrated in 28/30 ( 93 % ) typhoid patients , 0/11 bacteremic patients ( E coli or S paratyphi A ) and 0/15 asymptomatic individuals . - pubmed
Typhoid patients tested on admission or at discharge showed similar high reactivity rates to ELISA . - pubmed
Lithium ion does not protect brain against transient ischemia in gerbils . - pubmed
We examined the effects of lithium chloride on the morphologic outcome after 5 minutes of cerebral ischemia induced in gerbils by occluding both common carotid arteries under brief halothane anesthesia . - pubmed
Subgingival microbiota in squirrel monkeys with naturally occurring periodontal diseases . - pubmed
To evaluate the effects of late thrombolysis on left ventricular volume and function in acute myocardial infarction , two - dimensional echocardiography and radionuclide angiography were performed before discharge and after 1 year of follow - up study in 34 patients with acute anterior myocardial infarction . - pubmed
A 65 - year - old man had painless progressive proptosis of five years ' duration in his left eye . - pubmed
Symptoms of oestrogen deficiency in women with oestradiol implants . - pubmed
Intestinal microflora of the newborn rat as related to mammary , faecal , and vaginal Staphylococci strains isolated from the dam . - pubmed
To determine the relative importance of maternal microflora ( faeces , vagina , and teats ) in the contamination of newborn rats , strains of staphylococci from six different families ( dam + litter ) were isolated . - pubmed
The staphylococci strains found in the gut of the newborn rat originated first from the teats and thereafter from the faeces . - pubmed
The IG lymphoma encompassed a heterogeneous group of patients with varying prognoses but the overall survival curve was indistinguishable from that of HG lymphoma . - pubmed
Mild anemia was common and occurred in 40 - 50 % of the patients . - pubmed
In conclusion , the characteristic features of NHL in Taiwan include : ( 1 ) a high proportion of HG lymphoma and low proportions of LG and follicular lymphomas ; ( 2 ) a heterogeneous patient composition of IG lymphoma with an unfavorable overall prognosis. - pubmed
In approximately 80 % of patients with scirrhous carcinoma of the stomach , recurrence of cancers occurs even after potentially curative resection , and recurrence most frequently occurs in the form of peritoneal metastasis . - pubmed
We performed intraoperative peritoneal cytology on patients with scirrhous carcinoma of the stomach . - pubmed
Free cancer cells were demonstrated in the Douglas cavity in 16 of 32 ( 50 % ) patients who underwent potentially curative gastrectomy . - pubmed
The postoperative 5 - year survival rate was 23 % in patients without detectable free cancer cells in the peritoneal cavity , compared with only 9 % in patients with microscopic evidence of intraperitoneal free cancer cells . - pubmed
Therefore , we have applied hyperthermic continuous peritoneal perfusion ( CHPP ) on patients with scirrhous carcinoma of the stomach in order to develop a surgical adjuvant therapy effective for the prevention of recurrence of peritoneal involvement . - pubmed
These animals were hemodynamically evaluated at 3 to 6 months after operation and found to have no resting gradients or any degree of aortic regurgitation . - pubmed
Involvement of opioid and other systems in ethanol abstinence audiogenic seizures in the rat ? - pubmed
We have studied 42 subjects , including 6 healthy controls , 6 ileal resection subjects , 15 ulcerative colitis patients , and 15 patients with unresected ileal Crohn ' s disease . - pubmed
[ Osteomyelitis caused by Pasteurella multocida following dog bite . - pubmed
Although the causes of essential hypertension remain obscure , 2 different mechanisms for long - term vasoconstriction that sustain diastolic hypertension in the experimental and clinical forms of primary aldosteronism and renovascular hypertension can also be identified and quantified among patients with essential hypertension . - pubmed
Depending on the state of sodium balance , these 2 mechanisms contribute reciprocally to maintenance of arteriolar tone in experimental models , in both normal and hypertensive people , and in patients with congestive heart failure . - pubmed
In vivo genotoxicity of nitrates and nitrites in germ cells of male mice . - pubmed
Effects of both sodium nitrate ( doses of 600 and 1200 mg / kg / day for 3 days ) and sodium nitrite ( doses of 60 and 120 mg / kg / day for 3 days ) on spermatids of mice were investigated by measuring unscheduled DNA synthesis ( UDS ) 17 days after the end of treatment , and sperm - head abnormality 11 and 17 days after the end of treatment . - pubmed
Total mixed diets were 40 % corn silage ( DM basis ) , 15 % alfalfa hay , and 45 % concentrate mix . - pubmed
[ T and B lymphocyte function of patients with infectious complications after surgery for congenital heart defects ] . - pubmed
The parameters of T- and B - lymphocyte system were studied in 65 patients with congenital heart defects aged from 2 to 31 years with infectious complications after operation . - pubmed
We encountered eight patients with epidermolysis bullosa ( EB ) simplex of the Dowling - Meara type , who presented in infancy with severe blistering and were originally clinically thought to have recessive dystrophic EB . - pubmed
However , in two of the three older patients , the development of severe disabling hyperkeratosis of the palms and soles has been a prominent feature . - pubmed
The correct diagnosis of EB simplex was initially not made in five patients , because , on routine histologic examination , the blister was apparently subepidermal . - pubmed
Three subjects with Graves ' disease , three with toxic multinodular goitre and three with euthyroid multinodular goitre were sampled every hour for 24 h. The results obtained were compared to those from five euthyroid control subjects . - pubmed
The same tumor size dependence was found for the relative Tumak uptake in the other mouse organs studied ( e.g. - pubmed
Polychlorinated biphenyl- and triphenyl - induced gastric mucosal hyperplasia in primates . - pubmed
Polychlorinated biphenyl or triphenyl ingestion by subhuman primates for 3 months produced hyperplasia and dysplasia of the gastric mucosa . - pubmed
A small intranuclear virus recovered from lymphatic tissue of a bovine with malignant lymphoma . - pubmed
Induction of embryonic death in sheep by intrauterine injection of a small volume of normal saline . - pubmed
Methylmalonic aciduria and vitamin B12 deficiency in the rat . - pubmed
Disorders of serum protein catabolism in patients with tubular proteinuria , the nephrotic syndrome , or uremia . - pubmed
The present study was directed toward determining the role of the kidney in the metabolism of various classes of serum proteins and to define the urinary protein excretion patterns and the pathogenesis of disorders of protein metabolism in patients with proteinuria . - pubmed
Three distinct disorders of protein metabolism were noted in patients with renal tubular disease and tubular proteinuria , glomerular disease ( the nephrotic syndrome ) , and disease involving the entire nephrons ( uremia ) , respectively . - pubmed
Relationships between headache and amine changes after administration of reserpine to migrainous patients . - pubmed
[ Some data on the role of serotonin and acetylcholine in the pathogenesis of cardiac arrhythmia in children ] . - pubmed
Efficacy of desipramine in endogenomorphically depressed patients . - pubmed
This study was designed to test the hypothesis that there are 2 biochemical subgroups of ' endogenously ' depressed patients -- serotonin - deficient and noradrenalin - deficient groups -- which respond differently to antidepressants depending on relative blockade of serotonin vs. norepinephrine ( NE ) reuptake . - pubmed
Patients with pervasive anhedonia and autonomy of depressed mood ( endogenomorphic depressives ) were treated first with the noradrenergic agent desipramine ( DMI ) , then , if still depressed , such patients were randomized double - blind to continued DMI or clomipramine ( CMI ) , a primarily serotonergic agent . - pubmed
Of 34 such endogenomorphically depressed patients 2 responded during a placebo period and 5 dropped out . - pubmed
Eleven of the endogenomorphically depressed patients also met Research Diagnostic Criteria for situational depression ( reactive ) . - pubmed
Effects of hypoxia on the kinetic and morphological characteristics of human melanoma cells grown as colonies in semi - solid agar medium . - pubmed
An investigation was made of the cell populations that occur in the sequential strata of human melanoma ( MM96 ) colonies . - pubmed
Studies conducted in our laboratory relating to the development of immune processes in B vitamin deficiency states of experimental animals have been reviewed . - pubmed
To study the clinical and physiologic manifestations of the grain fever syndrome and the potentially pathogenic role of complement activation , 12 subjects ( six grain workers and six healthy non - grain workers ) underwent inhalation provocations with airborne grain dust . - pubmed
Fever developed in four grain workers and two controls . - pubmed
Leukocytosis , ranging between 11,700 and 24,300 leukocytes / mm3 with left shift , developed in five grain workers and five controls . - pubmed
Relationship of exercise capacity to resting left ventricular performance and basal plasma norepinephrine levels in patients with congestive heart failure . - pubmed
Seventeen patients with chronic congestive heart failure ( CHF ) were studied to assess the relationship of resting left ventricular function , as measured by noninvasive and invasive methods , to maximal exercise capacity , as measured by peak total body oxygen consumption ( VO2 ) . - pubmed
Supine basal plasma norepinephrine ( NE ) was also measured to evaluate its relationship to the severity of heart failure and to determine whether it may be a better predictor of exercise capacity in patients with CHF than the more commonly employed noninvasive and invasive tests of left ventricular function . - pubmed
The supine basal plasma NE , which was elevated in these 17 patients ( 612 + /- 100 pg / ml ) , had an inverse relationship with stroke work index ( r - -0.70 , p less than 0.01 ) and stroke index ( r = -0.83 , p less than 0.001 ) and a positive correlation with right atrial pressure ( r = 0.81 , p less than 0.001 ) . - pubmed
Influence of 15 retinoic acid amides on urinary bladder carcinogenesis in the mouse . - pubmed
A series of experiments was conducted to determine the efficacy of 15 synthetic retinoic acid amides ( retinamides ) as inhibitors of chemical carcinogenesis of the urinary bladder in C57BL / 6 x DBA / 2F1 mice . - pubmed
An analysis of the features of lower respiratory diseases ( LRD ) associated with Respiratory Syncytial Virus ( RSV ) in 21 children aged 1 - 23 months , indicated that the clinical features did not differ appreciably from those described for LRD due to other infective agents . - pubmed
Streptococcus pneumonia and Klebsiella pneumoniae respectively , were isolated from blood culture in the two cases with lobar pneumonia alone . - pubmed
The results of complex diagnosis and treatment in 237 patients with obstructive cholangitis are discussed . - pubmed
Steady - state pharmacokinetics of cyclosporine in renal transplant patients : does an influence of age or body weight exist ? - pubmed
Distal accentuation of conduction slowing distinguished these patients from those with Charcot - Marie - Tooth polyneuropathy type 1A , chronic inflammatory polyneuropathy , and from controls , as demonstrated by regression of distal motor latency on proximal conduction velocity . - pubmed
These results give a clear rationale for the use of in vitro expanded TIL from NSCLC in protocols of adoptive immunotherapy in patients with residual disease following surgery . - pubmed
Acute toxicity of deltamethrin and dieldrin to Oreochromis niloticus ( LIN ) . - pubmed
GABA and phosphatidylserine in human photosensitivity : a pilot study . - pubmed
Previous experimental studies have shown that the simultaneous administration of gamma - aminobutyric acid ( GABA ) and phosphatidylserine ( PS ) can exert an anticonvulsant activity in different seizure models ; moreover , a preliminary trial showed some effect of the association GABA - PS in patients with absence seizures . - pubmed
The aim of this study was to investigate the antiepileptic properties of GABA - PS in the model of human photosensitivity . - pubmed
Nine patients with epilepsy associated with an EEG pattern of photoconvulsive response at intermittent photic stimulation entered a 3 - day study . - pubmed
These results indicate that a single acute administration of GABA - PS has no effect in the human photosensitivity model , and suggest that the efficacy of GABA - PS in human epilepsy , as shown by a preliminary investigation , may possibly require chronic administration . - pubmed
[ Detection of mycobacterial DNA by in vitro enzymatic amplification in lung nodular lesions in a patient with ovarian immature teratoma ] . - pubmed
Platinum - based chemotherapy is still the cornerstone in the chemotherapeutic approach of ovarian cancer patients . - pubmed
Hormonal therapy continues to be an important component of treatment of patients with advanced or recurrent endometrial cancer . - pubmed
Peripheral blasts recovered from patients with acute myelogenous leukaemia ( AML ) were efficiently lysed by interleukin-2 ( IL-2 )- activated heterologous natural killer ( NK ) cells in vitro . - pubmed
OBJECTIVE -- To analyse the natural history of progressive supranuclear palsy ( PSP or Steele - Richardson - Olszewski syndrome ) and clinical predictors of survival in 24 patients with PSP confirmed by necropsy , who fulfilled the NINDS criteria for a neuropathological diagnosis of typical PSP . - pubmed
The patients ' mean age at onset of PSP was 63 ( range 45 - 73 ) years . - pubmed
RESULTS -- The most frequent clinical features ( occurring in at least 75 % of the patients ) were early postural instability and falls , vertical supranuclear palsy , akinetic - rigid predominant parkinsonian disorder characterised by symmetric bradykinesia and axial rigidity unrelieved by levodopa , pseudobulbar palsy , and frontal release signs . - pubmed
Fractures occurred in 25 % of the patients but were unrelated to the severity of the gait or to the presence of falls . - pubmed
Onset of falls during the first year are emphasised , as they could lead to an early diagnosis and influence the prognosis of patients with PSP . - pubmed
Whether appropriate treatment of the dysphagia could prolong the survival of PSP patients needs to be explored . - pubmed
Six adult female patients ( mean age , 41 yr ) with Nelson ' s syndrome were studied . - pubmed
A 36 - year - old man with a history of hypertrophic obstructive cardiomyopathy presented to the emergency room with " stabbing " chest pain . - pubmed
In patients with such ascending testes , an abnormal development or accidental trauma of the genitofemoral nerve may be involved in testicular ascent . - pubmed
[ Gastric antral vascular ectasia ( GAVE ) in a patient with primary biliary cirrhosis : seven - year follow - up ] . - pubmed
The complex manifests very much higher toxicity ( 200 - 1400 times ) against human tumor cells ( CEM , MCF-7 , HepG2 ) in vitro and surpasses TCDD in selectivity . - pubmed
Prediction of outcome in intensive care unit trauma patients : a multicenter study of Acute Physiology and Chronic Health Evaluation ( APACHE ) , Trauma and Injury Severity Score ( TRISS ) , and a 24 - hour intensive care unit ( ICU ) point system . - pubmed
OBJECTIVE : To conduct a multicenter study to validate the accuracy of the Acute Physiology and Chronic Health Evaluation ( APACHE ) II system , APACHE III system , Trauma and Injury Severity Score ( TRISS ) methodology , and a 24 - hour intensive care unit ( ICU ) point system for prediction of mortality in ICU trauma patient admissions . - pubmed
Lamivudine therapy of hepatitis B virus - related liver disease : cirrhosis , posttransplantation recurrence , and de novo infection . - pubmed
In contrast , in the recently published OASIS-2 study , outcome in patients with unstable angina pectoris was significantly better with hirudin than with heparin . - pubmed
BACKGROUND : Cytarabine is an essential drug for inducing remission of acute myelogenous leukemia , and it is also one the most effective drugs used as salvage therapy for patients with all types of relapsed acute leukemia . - pubmed
Nevertheless , there is considerable room for improvement in the treatment of patients with relapsed leukemia in terms of both the reinduction rate and the duration of response . - pubmed
METHODS : Fifty - five adults with relapsed or refractory acute leukemia or the blastic phase of chronic myelogenous leukemia ( CML ) received salvage therapy with the FLAM regimen , which consisted of fludarabine , cytarabine , and increasing doses of mitoxantrone . - pubmed
Overall , the complete response rate was 27.3 % ( 15 of 55 patients , including 4 of 17 with acute myelogenous leukemia [ AML ] , 4 of 12 with acute lymphocytic leukemia [ ALL ] , and 7 of 26 with the blastic phase of CML ) . - pubmed
METHODS : This was a prospective cohort study of eligible patients with pulmonary embolism managed as outpatients using dalteparin ( 200 U / kg s / c daily ) for a minimum of five days and warfarin for 3 months . - pubmed
Patients were followed for three months for clinically apparent recurrent venous thromboembolism and bleeding . - pubmed
CONCLUSIONS : This prospective study suggests that outpatient management of pulmonary embolism is feasible and safe for the majority of patients . - pubmed
UNLABELLED : The authors evaluate gastric emptying in diabetic patients and follow up selected factors which may influence it . - pubmed
The differences of prevalence of infection according to age groups for A. - pubmed
The prevalence of hookworm infection increased steadily with age to reach its maximum ( 37.7 % ) in adulthood ( & gt ; 18 years ) , while A. - pubmed
In wet highland the prevalence of infection of A. - pubmed
Scant information is available about the outcomes of patients with synchronous bilateral lung cancers ( SBLC ) treated with radiation . - pubmed
We report on 32 patients with SBLC who were treated for palliation by external beam irradiation during a 19 - year period . - pubmed
Between April 1994 and March 1997 , 143 children ( age range , 1 - 15 years ) with newly diagnosed acute lymphoblastic leukemia ( ALL ) , except for those patients with t(9;22 ) , were treated according to protocol-94 of the Osaka Childhood Leukemia Study Group . - pubmed
Nineteen patients with T - cell ALL were treated with the protocol for the UHRG . - pubmed
BACKGROUND : Mother - to - child transmission ( MTCT ) of HIV infection is one of the most tragic consequences of the HIV epidemic , especially in resource - limited countries , resulting in about 650 000 new paediatric HIV infections each year world - wide . - pubmed
This is one of several reviews assessing the available evidence for preventing HIV transmission from an HIV - infected woman to her child . - pubmed
No clear differences could be established when comparing samples from patients with different tumor Gleason grades . - pubmed
METHODS : Fifty - six ankles ( fifty - two patients ) with a tibial plafond fracture were treated with a uniform technique consisting of application of a monolateral hinged transarticular external fixator coupled with screw fixation of the articular surface . - pubmed
Thirty - one patients with thirty - five involved ankles returned between five and twelve years after the injury for a physical examination , assessment of ankle pain and function with the Iowa Ankle Score and Ankle Osteoarthritis Scale , assessment of general health status with the Short Form-36 ( SF-36 ) , and radiographic examination of the ankle . - pubmed
Random Amplification of Polymorphic DNA ( RAPD ) assay was used to study DNA typing of 24 strains of S. - pubmed
OBJECTIVE : Thirty - eight patients of laryngeal cancer were treated by extended frontal - lateral laryngectomy and the results were evaluated . - pubmed
METHODS : Thirty - eight patients with laryngeal cancer were treated by frontal - lateral laryngectomy and the laryngeal defects were reconstructed by epiglottic flap , bi - pedicle and bi - muscle flap and epiglottic flap plus bi - pedicle and bi - muscle flap from February 1988 to February 2000 . - pubmed
Frontostriatal abnormalities in adolescents with bipolar disorder : preliminary observations from functional MRI . - pubmed
OBJECTIVE : This study investigated whether the functional abnormalities in prefrontal systems observed in adult bipolar disorder are manifested in adolescents with this illness . - pubmed
METHOD : Ten adolescents with bipolar disorder and 10 healthy comparison subjects participated in a color - naming Stroop task during event - related functional magnetic resonance imaging . - pubmed
In the bipolar disorder subjects , depressive symptoms correlated positively with signal increases in the ventral striatum . - pubmed
CONCLUSIONS : These findings suggest the presence of dysfunction in the subcortical portions of the frontostriatal circuits in adolescents with bipolar disorder . - pubmed
In an ongoing CADASIL study , we noted a number of patients with early acute myocardial infarction ( before the age of 50 years ) , as well as patients with electrocardiogram ( ECG ) abnormalities . - pubmed
Method for adapting the virus of rinderpest to rabbits . - pubmed
ANTIBODIES PRODUCED BY GUINEA PIGS INFECTED WITH FOOT - AND - MOUTH DISEASE VIRUS . - pubmed
We are investigating the morphogenesis of foot - and - mouth disease virus and African swine fever virus by the use of high - pressure freezing of infected cells . - pubmed
Therefore regarding daily clinical practice , HRT certainly remains useful to control the symptoms of oestrogen deficiency in recently menopausal patients , but it should definitively no longer be recommended for long - term treatment . - pubmed
[ Acute thrombocytopenic purpura with meningeal hemorrhage , during chicken pox , cured by splenectomy ] . - pubmed
METHODS : We studied 31 patients with endoscopy - negative GERD , 15 patients with erosive RE , and 15 asymptomatic controls . - pubmed
The role of craniospinal irradiation in adults with a central nervous system recurrence of leukemia . - pubmed
BACKGROUND : Although central nervous system ( CNS ) prophylaxis in patients with leukemia has reduced the incidence of CNS disease recurrence , it still is reported to occur in approximately 5 - 10 % of cases , resulting in a median survival of 6 months . - pubmed
Craniospinal irradiation ( CSI ) has been shown to improve survival in children who develop a CNS recurrence of acute lymphocytic leukemia ( ALL ) . - pubmed
However , to the authors ' knowledge , the role of CSI in adults with a CNS recurrence of leukemia is unknown . - pubmed
METHODS : A retrospective review of adult patients treated with CSI for a CNS recurrence of leukemia identified 16 patients treated between 1986 and 2001 . - pubmed
The diagnoses included seven patients with acute myelogenous leukemia ( AML ) , eight patients with ALL , and one patient with chronic myelogenous leukemia in blast crisis . - pubmed
All patients had achieved a complete disease remission prior to the CNS recurrence . - pubmed
Eleven patients had an isolated CNS recurrence and 5 patients had concurrent disease identified in the blood / bone marrow . - pubmed
RESULTS : One patient failed to complete radiation treatment because of disease progression . - pubmed
No CNS recurrences occurred , but there were 11 bone marrow failures , 2 patients without recurrence at & gt ; 5 years , and 3 deaths without a documented site of failure . - pubmed
However , the eradication of disease in the CNS was not found to be effective at preventing disease recurrence in the bone marrow , and despite improved control of disease in the CNS , adult patients with a CNS recurrence still had a poor prognosis . - pubmed
Dried blood - spot test monitors HIV treatment . - pubmed
Prospective protective role of melatonin against arsenic - induced metabolic toxicity in Wistar rats . - pubmed
Arsenic treatment ( as sodium arsenite ) of male Wistar rats ( weighing 130 - 150 g ) at a dose of 5.55 mg kg(-1 ) body weight ( equivalent to 35 % of LD(50 ) ) ( i.p . ) - pubmed
Factors such as less advanced age , the presence of fewer comorbid conditions , or a less florid inflammatory response among HIV - infected individuals may account for differences in outcome of invasive PD . - pubmed
PURPOSE : We investigated patient outcome and factors affecting obliteration rate after radiosurgery in cerebral arteriovenous malformations ( AVM ) . - pubmed
MATERIAL AND METHODS : We have treated 110 patients with cerebral AVM with linac - based radiosurgery ( RS ) . - pubmed
Fifty - two patients experienced hemorrhage prior to RS . - pubmed
Neurological dysfunction improved / completely dissolved or remained stable in 95 % of patients . - pubmed
RESULTS : Of the 70 patients , 36 had colorectal liver metastasis , 24 had cholangiocarcinoma , 4 had hepatocellular carcinoma , and the remaining 6 had other tumors . - pubmed
Postoperative morbidity ( 87 % versus 35 % , P & lt ; 0.001 ) and mortality ( 20 % versus 5 % , P = 0.108 ) were observed more frequently in patients with preoperative obstructive jaundice than in those without jaundice . - pubmed
Survival for patients with colorectal liver metastasis undergoing left hepatic trisectionectomy with concomitant partial resection of the remnant liver was similar to those without this concomitant procedure . - pubmed
Concomitant partial resection of the remaining liver appears to be safe and offers the potential for cure in patients with colorectal metastasis affecting all liver segments . - pubmed
Tolerability to 1 - year treatment with once - daily molsidomine in patients with stable angina . - pubmed
Prolonged - release molsidomine 16 mg once daily ) QD ( has proved effective in the short - term treatment of patients with stable angina . - pubmed
A total of 320 patients with stable angina were treated for 1 year with molsidomine 16 mg QD administered open label as monotherapy or add - on therapy , when beta blockers and/or calcium antagonists were prescribed concomitantly ) in 128 patients , ie , 40 % of cases ) , depending on the severity of disease and/or local therapeutic policies . - pubmed
Headache accounted for 80.6 % of all drug - related AEs and required discontinuation of the drug in one quarter of patients who reported the symptom ( ie , 1.9 % of the 320 patients involved in the study ) . - pubmed
Molsidomine 16 mg QD administered for 1 y to patients with stable angina was well tolerated and remained effective during the entire treatment period , independent of age and concomitant antianginal therapy . - pubmed
Beneficial effects of LK-4 , an analog of dextromethorphan on lipopolysaccharide - induced sepsis in rats . - pubmed
, hypotension and tachycardia ) in rats treated with LPS . - pubmed
Contributions of histamine , prostanoids , and neurokinins to edema elicited by edema toxin from Bacillus anthracis . - pubmed
We evaluated the direct effect of ET on several cell types in vitro and tested the possibility that mediators of vascular leakage , such as histamine , contribute to edema in rabbits given intradermal ET . - pubmed
Re : The age - related decrease in testosterone is significantly exacerbated in obese men with the metabolic syndrome . - pubmed
After discussing alternative model systems like transgenic mouse models and canine xenografts , we argue that companion animals with spontaneous brain cancers offer a scientifically and ethically attractive system for preclinical testing of novel MG interventions . - pubmed
Ethical advantages and practical challenges of companion animal brain cancer trials are briefly discussed . - pubmed
In January 2005 , we implemented a treatment protocol that included intrapleural streptokinase ( STK ) for children with complicated parapneumonic empyema as an alternative to surgery . - pubmed
OBJECTIVES : To describe the results of intrapleural STK in the treatment of hospitalized children with complicated parapneumonic empyema and to compare these results with those of early thoracotomy . - pubmed
PATIENTS AND METHODS : Children with complicated parapneumonic empyema admitted between January 1st 2004 and October 1st 2005 were included . - pubmed
CONCLUSIONS : Intrapleural STK is a valid alternative for the treatment of children with complicated parapneumonic empyema . - pubmed
Nov. , from hamster dental plaque . - pubmed
, was isolated from dental plaque of golden hamsters fed with a high - carbohydrate diet . - pubmed
We present a case of retrobulbar hemorrhage complicating sub - Tenon 's anesthesia in a patient receiving oral anticoagulants . - pubmed
Although rhinsporidiosis caused by Rhinosporidium seeberi is known to mankind since hundred years , many aspects of this enigmatic disease have remained mysterious till date . - pubmed
Present status of surgical intervention for children with intractable seizures . - pubmed
We also discuss updates on identification and selection of children with severe refractory epilepsy . - pubmed
[ Influence of age , body weight and dose on sodium valproate plasma concentrations in children with epilepsy ] . - pubmed
METHODS : One hundred and thirty - two children with epilepsy ( age : 4 months-6 years , weight : 5 - 25 kg ) were enrolled . - pubmed
BACKGROUND : Hot flashes are a major cause of morbidity among postmenopausal women , including many survivors of breast cancer . - pubmed
The objective of this pilot trial was to assess the potential efficacy and safety of aprepitant for the treatment of hot flashes in this patient population . - pubmed
PATIENTS AND METHODS : Twenty - five postmenopausal women , aged & gt;/= 45 years , who were experiencing bothersome hot flashes ( & gt;/= 14 times per week ) for & gt;/= 1 month , were included . - pubmed
A tobacco hypersensitivity experiment showed that YM3 could eliminate carbofuran in soils effectively and safely . - pubmed
The role of deer mice and other species of Peromyscus as enzootic reservoirs for plague remains controversial . - pubmed
compared with that for the established plague vector Oropsylla montana Baker ( 10.63 % ; 95 % CI : 4.18 - 25.91 ) . - pubmed
At an early time of infection , colocalization of KSHV capsid with envelope was observed by immunofluorescence analysis , thus demonstrating endocytosis of intact enveloped virus particles . - pubmed
INTRODUCTION : Our aim was to evaluate the frequency and risk factors of posttransplant diabetes mellitus ( PTDM ) at our kidney transplant center , and to compare graft and patient outcomes between the kidney recipients with and without PTDM . - pubmed
All data including recipient and donor demographics , cause of end - stage renal disease , cytomegalovirus and hepatitis C virus antibody tests , and patient and graft outcomes were assessed in relation to PTDM . - pubmed
Moreover , impaired glucose tolerance was seen in 17 ( 8.4 % ) , 16 ( 7.9 % ) , 17 ( 8.4 % ) , and 19 ( 9.4 % ) patients at the corresponding times , respectively . - pubmed
Accordingly , 39 patients ( 19.2 % ) were diagnosed to have PTDM . - pubmed
The 5 - year patient and graft survival rates were not significantly different between the kidney recipients with and without PTDM . - pubmed
CONCLUSIONS : This study showed that PTDM is a common metabolic disorder in our kidney transplant patients . - pubmed
Implications of antioxidant enzymes in human gastric neoplasms . - pubmed
Gastric human neoplasms showed significant changes in antioxidant enzymes , that represent the first line in antioxidant protection against radical attack . - pubmed
Our results are important in enhancing the understanding of the role that these enzymes play in the promotion / suppression of the carcinogenesis cascade in human gastric mucosa . - pubmed
A repeat analysis was done with adjustments for age , sex , race , underlying cancer , catheter removal , APACHE III score , acute renal failure , neutropenia , and non - Candida albicans species . - pubmed
PATIENT : A 64 - year - old gentleman was treated for carcinoma rectum in our institution with neoadjuvant chemoradiation followed by low anterior resection and adjuvant chemotherapy . - pubmed
CONCLUSIONS : Our data suggest that either bronchial NO production in patients who underwent laryngectomy is very low , possibly due to alterations of the mucosa or oxidant production / inflammation , or that substantial contributions to FENO arise from the larynx , pharynx and mouth , raising FENO despite velum closure . - pubmed
The urinary sulfur partition in normal and cystinuric dogs fed labeled methionine . - pubmed
The most frequent antigens that cause HP worldwide are bird proteins ( pigeon breeders ' disease ) and bacteria ( Saccharopolyspora rectivirgula ) . - pubmed
OBJECTIVE : To discuss the practical aspects of safe physical activity and sports participation in children and adolescents with type 1 diabetes mellitus . - pubmed
Nonetheless , physical activity and participation in many individual and team sports is possible and highly recommended in the treatment of type 1 diabetes in children and adolescents . - pubmed
CASES : The use of this combined technique is described in 4 cases , including 2 patients with spinal cord injury and category IV pressure ulcers and 2 patients with extensive postsurgical wounds . - pubmed
RESULTS : Fifty - seven patients had hepatic complications , including radiological features of liver cirrhosis ( 25.9 % ) , thrombocytopenia ( 7.2 % ) , hyperbilirubinaemia ( 20.9 % ) and hepatic masses ( 2.9 % ) . - pubmed
CONCLUSION : Late hepatic dysfunction and cirrhotic change were often seen in Fontan patients . - pubmed
METHODS : We examined 39 patients with DTC who had a clinical history of at least 2 years and compared them with 25 patients who had a pathological diagnosis of NG after thyroidectomy . - pubmed
Kirkaldy native populations there , and to avoid the confusion of the damage that may be caused on O. - pubmed
geniculata will provide another source for wheat stem rust resistance breeding and for physical mapping of the resistance locus and crossover hot spots between wheat chromosome 5D and chromosome 5M(g)L of Ae . - pubmed
METHODS : A total of 64 keratocystic odontogenic tumours , arising in forty - six patients , were evaluated using the following parameters : association with nevoid basal cell carcinoma syndrome , gender , age at first diagnosis , race , anatomical location , symptoms , radiographic features , history of recurrence , association with teeth , and treatment . - pubmed
RESULTS : Keratocystic odontogenic tumours were more frequent among women than men ( 1:0.84 ) . - pubmed
Liver tumor models in transgenic zebrafish : an alternative in vivo approach to study hepatocarcinogenes . - pubmed
In the early experiments of carcinogen treatment , it has been found that the induced tumors in the zebrafish share many similar features with those of humans . - pubmed
With the recent development in transgenic technology , we are able to control the expression of a specific oncogene in targeted organs for generation of different tissue tumor models in zebrafish . - pubmed
In particular , the fusion of an oncogene and a color reporter , such as the green fluorescent protein , allows us to conveniently monitor transgenic tumors for their initiation , progression , metastasis and transplantation in the transparent zebrafish embryos , as demonstrated in this article with our newly established liver cancer models . - pubmed
A 42 - year - old female patient underwent mastectomy with axillary lymph node dissection for breast cancer in 2001 . - pubmed
Chronic arsenic exposure remains a human health risk ; however a clear mode of action to understand gene signaling - driven arsenic carcinogenesis is currently lacking . - pubmed
This study chronically exposed human lung epithelial BEAS-2B cells to low - dose arsenic trioxide to elucidate cancer promoting gene signaling networks associated with arsenic - transformed ( B - As ) cells . - pubmed
B - As injections into nude mice resulted in development of primary and secondary metastatic tumors . - pubmed
In summary , our excision - free optical biopsy technique is ideal for longitudinal microscopic analysis of animal skin and skin innervations in vivo and can be applied widely in preclinical models of chronic pain , allergies , skin cancers and a variety of dermatological disorders . - pubmed
In the present study , we investigated the effects of the Autographa californica nucleopolyhedrovirus ( AcMNPV ) infection on autophagy in SL - HP cell line from Spodoptera litura induced under amino acid deprivation . - pubmed
The results revealed that AcMNPV infection did not inhibit autophagy but triggered apoptosis under starvation pressure . - pubmed
METHODS : Genome - wide DNA methylation changes between relapse and remission in monocytes ( n = 6 ) and naive T helper cells ( Th0s ) ( n = 4 ) isolated from patients with MCNS were investigated using the microarray - based integrated analysis of methylation by isochizomers ( MIAMI ) method . - pubmed
Serratia marcescens associated ampullary system infection and septicaemia in a bonnethead shark , Sphyrna tiburo ( L. ) . - pubmed
Seventy - eight patients underwent deep hypothermia ( mean lowest temperature , 16.8 C + - 1.7 C ) and 143 patients underwent moderate hypothermia ( mean , 22.9 C + - 1.4 C ) before systemic circulatory arrest was initiated . - pubmed
OBJECTIVE : We aimed to assess sensitivity and specificity of the updated criteria for behavioral variant frontotemporal dementia ( bvFTD ) based on a large autopsy - confirmed cohort of patients with dementia . - pubmed
METHODS : Two hundred thirty - nine consecutive pathologically confirmed dementia patients , clinically assessed in a specialist cognitive unit were identified . - pubmed
Patients with predominant aphasia , motor disorders , or insufficient clinical information were excluded . - pubmed
RESULTS : The final study cohort comprised 156 patients with predominantly early - onset dementia . - pubmed
Patients with chronic renal failure in use of peritoneal dialysis ( PD ) are subject to various complications of the renal replacement therapy . - pubmed
This report describes the case of a patient who had a second squamous cell carcinoma ( SCC ) in the center of the skin island of a forearm flap raised approximately 6 years previously . - pubmed
METHODS : Affective ToM was assessed with the Reading the Mind in the Eyes task in 35 PD patients and 35 healthy controls . - pubmed
Patients were distinguished in early PD and moderate PD according to their scores in the Hoehn and Yahr Staging Scale . - pubmed
Influence of Salmonella enterica serovar Enteritidis infection on the composition of chicken cecal microbiota . - pubmed
BACKGROUND : Infection of newly hatched chicks with Salmonella enterica serovar Enteritidis ( S. - pubmed
Enteritidis infection influences the composition of the cecal microbiota in chickens but these changes are minor in nature and should be understood more as an indirect consequence of infection and inflammation rather than a positively selected evolutionary trait . - pubmed
[ IAG regimen for patients with refractory / relapsed acute myeloid leukemia ] . - pubmed
43 children , 3 - 18 year old ( 23 females , median age 10 years ) , presenting with recurrent headache from April , 2011 to January , 2012 , were enrolled . - pubmed
26 patients ( 60.5 % ) had headache with migraine features ( 11 had Tension type headache and 4 had non - specific headaches ) . - pubmed
Fresh frozen plasma ( FFP ) has been used in human OP pesticide poisoning which prompted us to investigate the in vitro kinetics of OP nerve agent degradation by FFP . - pubmed
FFP does not seem to be suitable for detoxifying relevant agent concentrations in case of human poisoning by V - type nerve agents . - pubmed
Clinical symptoms of respiratory distress resolved in the early postoperative period , and the patient became hemodynamically stable . - pubmed
[ Effects of non - surgical periodontal treatment on clinical response , serum inflammatory parameters , and metabolic control of type 2 diabetes patients with moderate to severe periodontitis ] . - pubmed
OBJECTIVE : To evaluate the effects of periodontal treatment on the clinical response , systemic inflammatory parameters , and metabolic control of type 2 diabetes patients with moderate to severe periodontitis . - pubmed
CONCLUSION : Non - surgical periodontal treatment can effectively improve periodontal status , circulating inflammatory status , and metabolic control of diabetic patients with moderate to severe periodontitis . - pubmed
The first case of bacteraemia due to non - O1 / non - O139 Vibrio cholerae in a type 2 diabetes mellitus patient in mainland China . - pubmed
Bacteraemia due to non - O1 / non - O139 Vibrio cholerae is rarely documented in mainland China . - pubmed
The feedback negativity ( FN ) , an ERP index of reward evaluation , was recorded in 34 unmedicated depressed individuals and 42 never - depressed controls during a laboratory gambling task . - pubmed
Ventral striatal ( VS ) activation to reward was recorded in a separate fMRI session , using an identical task , among a subgroup of 24 depressed individuals and a comparison group of 18 non - depressed controls . - pubmed
In patients with significant emesis co - occurring during an attack , additional antiemetics such as metoclopramide or domperidone may be administered . - pubmed
The treatment success of the individual patient is difficult to predict both in acute and prophylactic migraine treatment . - pubmed
The committee recommended , though not unanimously , that ( 1 ) the current data does not support the conclusion that naproxen has a lower risk of thrombotic events than other NSAIDs ; ( 2 ) there is no latency period for the risk of cardiovascular thrombotic events ; ( 3 ) there are some patient populations at increased risk for events ; and ( 4 ) equipoise remains in the major ongoing trial designed to address these issues further . - pubmed
The objective of this study was to evaluate if peritumoral ( PT ) perfusion parameters obtained from dynamic susceptibility weighted contrast enhanced perfusion MRI can predict overall survival ( OS ) and progression free survival ( PFS ) in patients with newly diagnosed glioblastoma multiforme ( GBM ) . - pubmed
Twenty - eight newly diagnosed GBM patients , who were treated with resection followed by concurrent chemoradiation and adjuvant chemotherapy , were included in this study . - pubmed
Our study found posttreatment , not pretreatment , PT perfusion parameters can be used to predict OS and PFS in patients with newly diagnosed GBM . - pubmed
Intravesical instillation of amikacin for treatment of a lower urinary tract infection caused by Pseudomonas aeruginosa in a dog . - pubmed
CASE DESCRIPTION : A 9 - year - old neutered male Golden Retriever was evaluated because of recurrent lower urinary tract infection subsequent to placement of a permanent cystostomy tube . - pubmed
CLINICAL RELEVANCE : In this dog , treatment of a lower urinary tract infection caused by a multidrug - resistant strain of P aeruginosa was successfully achieved with intravesical instillation of amikacin . - pubmed
Intravesical instillation of antimicrobials may be a viable treatment option for dogs with lower urinary tract infections caused by multidrug - resistant bacteria . - pubmed
CONCLUSION : Limited published data exists reporting the effectiveness of measures in the treatment of xerostomia in cancer patients . - pubmed
DESIGN : In humans , we mined genome - wide meta - analysis data sets to examine purinergic signaling genes for association with glycemic traits and type 2 diabetes . - pubmed
Generation of human acute lymphoblastic leukemia xenografts for use in oncology drug discovery . - pubmed
The establishment of reproducible mouse models of acute lymphoblastic leukemia ( ALL ) is necessary to provide in vivo therapeutic test systems that recapitulate human ALL , and for amplification of limited amounts of primary tumor material . - pubmed
The protocol includes injection of primary patient tumor specimens into mice with subsequent serial passaging of the tumors by retransplants of cells harvested from the mouse bone marrow and spleen . - pubmed
PATIENTS AND METHODS : Seventy - five patients with extremity trauma suspicious for arterial injury were examined by color Doppler USG just before angiography . - pubmed
CONCLUSIONS : Color Doppler USG can be used as a reliable modality with acceptable sensitivity and specificity values to screen hemodynamically stable patients with limb trauma suspicious for arterial injury . - pubmed
The use of dynamic susceptibility contrast ( DSC ) MRI to automatically classify patients with first episode psychosis . - pubmed
The aim of this work is to automatically discriminate first episode psychosis patients and normal controls on the basis of brain perfusion employing a support vector machine ( SVM ) classifier . - pubmed
In conclusion , we found evidence that brain perfusion could be used as a potential marker to classify patients with psychosis , who show reduced blood flow and volume in respect to normal controls . - pubmed
Rosuvastatin Decreases Mean Platelet Volume in Patients With Diabetes Mellitus . - pubmed
We evaluated the effects of rosuvastatin on mean platelet volume ( MPV)--a marker for platelet activity -- in patients with diabetes mellitus ( DM ) on rosuvastatin medication . - pubmed
The antiplatelet activation properties of high - dose rosuvastatin treatment in patients with DM are not lipid dependent . - pubmed
Accumulated evidence from experimental animal models suggests that neuroplastic changes at the dorsal horn are critical for the maintenance of various chronic musculoskeletal pain conditions . - pubmed
These data reveal that chronic musculoskeletal pain in humans is associated with discrete alterations in the anatomy of the medullary dorsal horn , as well as its afferent and efferent projections . - pubmed
Notably , plasma thiocyanate levels are increased in smokers , and leukocyte - driven protein carbamylation occurs both within human and animal atherosclerotic plaques , as well as on plasma proteins . - pubmed
Characterization of microRNA expression profiling in peripheral blood lymphocytes in rats with experimental autoimmune uveitis . - pubmed
OBJECTIVE AND DESIGN : We aimed to investigate the alterations of microRNA ( miRNA ) genomics in peripheral blood lymphocytes in experimental autoimmune uveitis ( EAU ) rats versus control samples . - pubmed
RESULTS : The results indicated that 36 miRNAs were upregulated and 31 miRNAs were downregulated in EAU rats versus normal samples . - pubmed
CONCLUSIONS : Our findings show that the differentially expressed miRNAs in EAU rats were closely associated with immune signaling pathways and may be applied in early prevention , prognosis and possible therapy in uveitis , indicating that miRNAs play an important role in the development of uveitis . - pubmed
The effects of intravenous fosaprepitant and ondansetron in the prevention of postoperative nausea and vomiting in patients who underwent lower limb surgery : a prospective , randomized , double - blind study . - pubmed
All patients received postoperative epidural fentanyl for pain control . - pubmed
METHODS : Between 2006 and 2014 , six patients affected by infection and necrosis after Achilles tendon open repair underwent multi - tissutal reconstruction by a composite radial forearm free flap including a vascularized FCR tendon . - pubmed
METHODS : In total , 47 overweight and obese men who had been referred for suspected OSA underwent polysomnography and were classified based on the apnea - hypopnea index ( AHI ) into three groups : no OSA , & lt ; 5 events / h ( n = 11 ) ; mild OSA , & gt;= 5 to & lt ; 15 events / h ( n = 8) ; and moderate - severe OSA , & gt;= 15 events / h ( n = 28 ) . - pubmed
The proportions of patients with MS were different between the three groups ( 18.2 % in no OSA ; 25 % in mild OSA , and 57.1 % in moderate - severe OSA ; p = 0.047 ) . - pubmed
Validation of Serological Antibody Profiles Against Human Papillomavirus Type 16 Antigens as Markers for Early Detection of Cervical Cancer . - pubmed
During the virus life cycle and in the process toward malignancy , different human papillomavirus ( HPV ) proteins are expressed , and they induce a host humoral immune response that can be used as a potential marker for different stages of the disease . - pubmed
Since the 1950s , there have been reports of loblolly pines showing reduced growth and increased mortality , particularly in central Alabama and western Georgia , United States ; the phenomenon is termed as southern pine decline ( SPD ) . - pubmed
Recently , the role of rhizophagous ( root - feeding ) insects in loblolly pine health within the context of SPD has come under greater scrutiny . - pubmed
Cerebral Glucose Metabolism and Dopaminergic Function in Patients with Corticobasal Syndrome . - pubmed
Safety and efficacy of vismodegib in patients with basal cell carcinoma nevus syndrome : pooled analysis of two trials . - pubmed
It is unclear whether BCCs arising in patients with BCCNS respond differently to vismodegib than in patients without BCCNS . - pubmed
We examined the best overall response rate ( BORR ) and adverse events ( AEs ) of vismodegib in patients with advanced BCC ( aBCC ) with and without BCCNS . - pubmed
RESULTS : Forty - one patients with BCCNS were included in the study : 22 from ERIVANCE BCC and 19 from the EAS . - pubmed
Investigator - assessed BORR in BCCNS groups ranged from 31 to 81 % in patients with locally advanced BCC ( n = 33 ) and was 50 % in patients with metastatic BCC ( n = 6 ) . - pubmed
Amenorrhea was observed in both patient cohorts and was reversible in two patients who discontinued treatment . - pubmed
High expression of miR-33a suppressed xenograft tumor growth and dissemination in nude mice . - pubmed
The downregulation of miR-33a was closely associated with advanced clinical stage , lymph node metastasis , and poor clinical outcomes in patients with GBC . - pubmed
BACKGROUND : Cellulite is a common aesthetic condition that affects almost every woman . - pubmed
METHODS : In this open - label , single - centre trial , 30 women presenting moderate or severe cellulite underwent 12 sessions of AWT on the gluteus and back of the thighs , over six weeks . - pubmed
In 28 patients ( 87.5 % ) , there was peritoneal fluid , which was blood in 14 patients ( hematoma in 11 patients and contrast material extravasation from active bleeding in 3 patients ) . - pubmed
CONCLUSION : A radiologic score is helpful for guiding the diagnosis and management ( surgical or conservative ) of gastric blunt traumatic injuries and stratify patients according to short - term outcomes . - pubmed
This systematic review discusses in vivo animal and human studies of the physiological and biochemical effects of chlorogenic acids ( CGAs ) on biomarkers of chronic disease . - pubmed
METHODS AND MATERIALS : For a cohort of 100 patients with STS of the extremity / trunk treated at our institution with preoperative RT followed by resection , 2 expert sarcoma pathologists evaluated the resected specimens for percent residual viable cells , necrosis , hyalinization / fibrosis , and infarction . - pubmed
The device - oriented composite end point of cardiac death , target - vessel myocardial infarction and target - lesion revascularization occurred in 13 ( 16 % ) patients treated with EES , in 7 ( 9 % ) patients treated with BES and in 16 ( 21 % ) patients treated with BVS . - pubmed
There was one late scaffold thrombosis throughout the trial in the BVS group , and no definite stent thrombosis in either EES or BES treated patients . - pubmed
Nephrogenic systemic fibrosis ( NSF ) , previously known as nephrogenic fibrosing dermopathy , is a rare complication of exposure to gadolinium - based contrast agents in patients who have significantly decreased renal function . - pubmed
Photopheresis has been tried with variable rates of improvement , and small numbers of cases ( 20 as of 2016 ) have been reported of NSF patients treated with photopheresis . - pubmed
We report a case of patient with nephrogenic systemic fibrosis who was treated with photopheresis and demonstrated significant lasting improvements . - pubmed
BACKGROUND : Enterovirus ( EV ) and herpes simplex virus 1 and 2 ( HSV1 and HSV2 ) are the main etiologic agents of central nervous system infections . - pubmed
RESULTS : We tested 87 CSF samples of patients with a clinical diagnosis of viral meningitis or encephalitis . - pubmed
Patients were excluded for & lt;2 years in the plan before the index date , any history of nAMD or diagnosis , or treatment for an ocular disease that could be confused with nAMD . - pubmed
Primary analysis compared BB with CCB patients with BB versus the other classes as secondary analyses . - pubmed
After controlling for covariates , patients on BB had a lower hazard for nAMD at both 90 and 180 days than patients on CCB ( HRs : 0.67 - 0.71 ; P & lt ; 0.01 for both ) and diuretics ( HRs : 0.55 - 0.62 ; P & lt ; 0.01 ) . - pubmed
A sensitivity analysis using propensity score matching yielded similar results with patients on BB significantly less likely to develop nAMD at 90 and 180 days ( HR : 0.70 - 0.76 ; P & lt ; 0.049 for both ) but not at 365 days ( HR : 0.88 ; P = 0.30 ) compared with patients on CCB . - pubmed
However , a few patients may develop different types of pain after herpetic lesions . - pubmed
We are reporting two patients who developed postherpetic hemicrania continua ( HC ) . - pubmed
Case 1 : a 54 - year - old woman had a 10 - month history of continuous left - sided pain with superimposed exacerbations . - pubmed
Case 2 : a 61 - year - old woman developed clinical features pertinent to PHN . - pubmed
We suggest that every patient with PHN should be asked for cranial autonomic features and a trial of indomethacin should be given in refractory herpes zoster neuropathy . - pubmed
For Japanese encephalitis positive patients , mean age was 36 ( range 4 - 80 ) . - pubmed
This study identified structural and functional brain connectivity alterations in two independent samples of patients along the posterior cortical atrophy ( PCA ) disease course . - pubmed
Twenty - one PCA patients and 44 controls were recruited from two expert centres . - pubmed
PCA patients showed distributed WM damage . - pubmed
METHODS : A large collection of RMR measurements and energy intake was assembled in mechanically ventilated and critically ill patients . - pubmed
Recent epidemiological studies suggest that human exposure to perfluoroalkyl substances ( PFASs ) may be associated with type 2 diabetes and other metabolic phenotypes . - pubmed
Prevalence of bone pain decreases as lymph node stage increases in nonsmall cell lung cancer patients . - pubmed
We investigated the appropriate use of bone imaging in nonsmall cell lung cancer ( NSCLC ) patients . - pubmed
One hundred seventy - seven consecutive NSCLC patients who had distant metastases at presentation and were admitted between January 2012 and April 2016 were retrospectively reviewed . - pubmed
Among patients with bone metastases , we explored bone pain , number of bone metastases , location of bone metastases , and clinical tumor ( T ) and lymph node ( N ) classification . - pubmed
Sixty - three patients had bone metastases . - pubmed
N0 and N2 - 3 patients were more likely to have multiple bone metastases ( p = 0.038 ) . - pubmed
Compared with patients who had a single bone metastasis , patients with multiple metastases had a significantly higher probability of having at least 1 bone metastasis located in the thorax or upper abdomen . - pubmed
All N0 patients have at least 1 bone metastasis in the thorax or upper abdomen . - pubmed
Clinical N0 NSCLC patients with bone metastasis are likely to have bone pain and have multiple bone metastases . - pubmed
N2 - 3 patients are more likely to have bone metastases but less likely to have bone pain . - pubmed
Objective : Patients with type 1 diabetes mellitus ( T1DM ) are insulin dependent . - pubmed
Participant : A 29 - year - old Hispanic woman with known history of long - standing , uncontrolled T1DM presented for evaluation of worsening dysphagia and dyspnea . - pubmed
This review focuses on recent advances in our understanding of ISC identity , behavior , and regulation during homeostasis and injury - induced repair , as revealed by two major animal models used to study regeneration of the small intestine : Drosophila melanogaster and Mus musculus . - pubmed
MATERIALS AND METHODS : We analyzed data from women treated in one center with adjuvant interstitial HDR brachytherapy for early - stage breast cancer . - pubmed
Treatment regimen was homogeneous for all women with treatment dose 32Gy in 8 fractions twice daily given to the tumor bed with interstitial HDR brachytherapy . - pubmed
Three DNA extraction methods were compared for relative yield and sensitivity of detection of CMV DNA : thermal shock , KOH Tris buffer , and DNA Extract All . - pubmed
Moderate to severe pancreatitis developed in 4 patients ( 0.9 % ) in the combination group , and 10 patients ( 2.3 % ) in the diclofenac - alone group ( relative risk 0.12 ; 95 % confidence interval 0.13 - 1.26 ; P = .12 ) . - pubmed
To our knowledge , this is the first report of natural infection of onion by B. - pubmed
BACKGROUND : Torquetenovirus ( TTV ) viremia is emerging as a promising tool to assess functional immune competence , to predict posttransplant immune - related complications , and eventually to customize immunosuppression . - pubmed
CONCLUSIONS : These findings provided us a valuable approach for detection and differentiation the HEV infection derived from genotypes 1 , 2 ( human ) or genotypes 3 , 4 ( zoonosis ) . - pubmed
Human Dendritic Cell Subsets , Ontogeny , and Impact on HIV Infection . - pubmed
Even though HCV infection morbidity rate in children is relatively low in comparison with the adult population , approximately 5 million children in the world have active HCV . - pubmed
Co - infection of Pneumocystis jirovecii and Aspergillus in a patient with idiopathic thrombocytopenic purpura . - pubmed
INTRODUCTION : Mortality risk and outcome in critically ill patients can be predicted by scoring systems . - pubmed
Acute kidney injury ( AKI ) is also one of the strongest factors negatively influencing patients ' fate . - pubmed
OBJECTIVES : We aimed to evaluate the value of MR - proADM in incident AKI and mortality prognostication among patients admitted to the intensive care unit ( ICU ) in comparison to commonly used scoring systems . - pubmed
35 patients ( 22 % ) developed AKI by 3 days post - ARDS diagnosis , and 25 ( 16 % ) died by 60 days post - ARDS diagnosis . - pubmed
METHODS : Ninety healthy controls , 30 patients with major depressive disorder ( MDD ) , 35 patients with mild cognitive impairment ( MCI ) , and 55 patients with ADD performed a Symbol Processing Task with 4 different symbol categories . - pubmed
RESULTS : Analyses revealed a higher symbol comprehension accuracy in healthy seniors than in MDD , MCI , and ADD patients , with the lowest accuracy rates shown by ADD patients . - pubmed
At last , nude mice xenograft was used to further investigate the anti - tumor effect of SMA / CORM-2 in vivo . - pubmed
In vivo , SMA / CORM-2 treatment remarkably suppressed tumor growth and lung metastasis in nude mice . - pubmed
PURPOSE : Surgical resection of primary tumor with regional lymphadenectomy remains the treatment of choice for patients with advanced human papillomavirus - negative head and neck squamous cell carcinoma . - pubmed
OBJECTIVE : To evaluate the presence of tau deposition and pathologic features of chronic traumatic encephalopathy ( CTE ) in young adult patients treated with focal cortical resections for drug - resistant epilepsy . - pubmed
METHODS : Sixty consecutive patients who had undergone surgical treatment for drug - resistant focal epilepsy between 18 and 45 years of age were identified ( 2010 - 2017 ) . - pubmed
A history of head trauma was reported in 19 patients . - pubmed
Three of these 4 patients had no significant history of head trauma ; 1 patient had multiple sports - related concussions . - pubmed
Diagnostic features of CTE were not detected in any patient ; however , the pathological evaluation for CTE was limited to a surgical specimen . - pubmed
All flaps survived , dental occlusion was achieved in all patients , no tumors recurred , masticatory function was normal without swallowing or speech alterations , and the transplanted bone hypertrophied and spontaneously remodeled , providing facial symmetry with good aesthetic results . - pubmed
Listeria monocytogenes is an important foodborne pathogen , causative agent of listeriosis . - pubmed
In addition , none of the strains which were not ascribed to L. - pubmed
Methods : Fibroblasts isolated from the hips of patients with AS were induced to osteogenesis . - pubmed
A proteoglycan - induced arthritis ( PGIA ) Balb / c mouse model was established in order to monitor sacroiliac joint ( SIJ ) inflammation and subsequent damage through magnetic resonance image . - pubmed
The patient has been alive for 15 months without recurrence . - pubmed
Long - Term Safety and Durability of Effect With a Combination of Olanzapine and Samidorphan in Patients With Schizophrenia : Results From a 1 - Year Open - Label Extension Study . - pubmed
However , as SARS - CoV-2 mutates , we need to constantly assess whether existing PCR - based assays will continue to detect all known viral strains . - pubmed
Sedentary behavior and cognitive impairment have a direct impact on patients ' outcomes . - pubmed
An energy metabolic disorder may be involved in the overlap of these comorbid conditions ( motoric cognitive risk ( MCR ) ) in patients with chronic obstructive pulmonary disease ( COPD ) . - pubmed
This protein was not disease - specific but could be a screening biomarker to detect MCR related to poor health outcomes of COPD patients . - pubmed
Food impaction mimicking dislodgment of a lumen - apposing metal stent in a patient undergoing endoscopic ultrasound - guided gallbladder drainage for acute cholecystitis . - pubmed
PURPOSE : Sedation management of trauma patients after damage control laparotomy ( DCL ) has not been optimized . - pubmed
We calculated the propensity for each patient to achieve DFC using age , gender , ISS , red blood cell transfusion , bowel discontinuity , abdominal vascular injury , and time to first takeback ; we then determined the effect of sedation exposure on rate of DFC by multivariate Cox regression , adjusted for propensity to achieve DFC . - pubmed
For each study , information was recorded regarding mouse strain and sex ; corticosterone sample matrix and quantification technique ; and whether the studies covered the research themes animal welfare , neuroscience , stress , inflammation , or pain ( the themes of specific interest in our consortium ) . - pubmed
METHODS : Patients with mRCC and spinal involvement from June 2005 to November 2018 were identified . - pubmed
RESULTS : One hundred patients with 685 spinal levels involved by mRCC were evaluated . - pubmed
Patients with smaller tumors ( < 4 cm ) and local spread had distribution of spinal metastases not significantly different from uniform ( P = 0.292 and P = 0.126 , respectively ) . - pubmed
Re : Results of a randomized trial of treatment modalities in patients with low or early - intermediate risk prostate cancer ( PREFERE trial ) . - pubmed
Tomatidine ameliorates obesity - induced non - alcoholic fatty liver disease in mice : Tomatidine improves hepatic steatosis in mice . - pubmed
In this study , we investigated how tomatidine ameliorates NAFLD in obese mice and evaluated the regulatory mechanism of lipogenesis in hepatocytes . - pubmed
Male C57BL / 6 mice were fed a high - fat diet ( HFD ) to induce obesity and NAFLD , and treated with tomatidine via intraperitoneal injection . - pubmed
Our results demonstrate that tomatidine significantly decreases body weight and fat weight compared to HFD - fed mice . - pubmed
In addition , tomatidine decreased hepatic lipid accumulation and improved hepatocyte steatosis in HFD - induced obese mice . - pubmed
Background : The increased survival of patients with multiple myeloma ( MM ) raises the question of kidney transplantation ( KT ) in patients with end - stage renal disease ( ESRD ) . - pubmed
Methods : We included 13 patients with MM or smoldering myeloma ( SMM ) and ESRD transplanted between 2007 and 2015 , including 7 MM with cast nephropathy , 3 with MM - associated amyloid light chain amyloidosis or light chain deposition disease and 3 SMM and compared them with 65 control - matched kidney - transplanted patients . - pubmed
Nine of the MM patients with KT were also compared with 63 matched MM patients on haemodialysis . - pubmed
Results : Pre - transplantation parameters were comparable , except for the duration of renal replacement therapy ( 57.8 versus 37.0 months ; P = 0.029 ) in MM versus control patients , respectively . - pubmed
The median MM graft and patient survival were 80.1 and 117.2 months , respectively , and were not significantly different from control patients , although mortality tended to be higher in the 10 symptomatic MM patients ( P = 0.059 ) . - pubmed
MM patients had significantly more viral and fungal infections and immunosuppressive maintenance therapy modifications while they received lower induction therapy . - pubmed
Two MM patients relapsed and two SMM cases evolved to MM after KT . - pubmed
Moreover , survival of MM with KT increased relative to control haemodialysed patients ( P = 0.002 ) . - pubmed
Conclusions : Selected MM patients may benefit from KT but need careful surveillance in the case of KT complications and MM evolution . - pubmed
The aim of this meta - analysis was to investigate whether the blood concentrations of patients with multiple sclerosis ( MS ) are associated with those of the healthy control group in terms of trace elements including zinc ( Zn ) , iron ( Fe ) , manganese ( Mn ) , magnesium ( Mg ) , selenium ( Se ) , and copper ( Cu ) . - pubmed
Pooled results using random - effects model indicated that the levels of Zn ( WMD = - 7.83 mcg / dl , 95 % CI = - 12.78 to - 2.87 , Z = 3.09 , P = 0.002 ) , and Fe ( WMD = - 13.66 mcg / dl , 95 % CI = - 23.13 to - 4.19 , Z = 2.83 , P = 0.005 ) were significantly lower in MS patients than in controls . - pubmed
However , it was found that levels of Mn ( WMD = 0.03 mcg / dl , 95 % CI = 0.01 to 0.04 , Z = 2.89 , P = 0.004 ) were significantly higher in MS patients . - pubmed
This meta - analysis revealed that the circulating levels of Zn and Fe were significantly lower in MS patients and that Mn level was significantly higher than those in the control group . - pubmed
However , it was found that there was no significant difference between MS patients and controls with regard to levels of Mg , Se , and Cu . - pubmed
A patient who died from oat - cell carcinoma of the lung had had abdominal pain and obstipation . - pubmed
Kinetic measurements of the serum appearance and disappearance of triglycerides in drug - treated rats suggest that the hypotriglyceridemic activity is due to a net inhibition of hepatic triglyceride synthesis . - pubmed
Preliminary experiments in rats on the mechanism of its hypoglycemic activity , observed in some diabetic hyperlipidemic patients , indicate that halofenate acts differently than conventional oral hypoglycemic agents . - pubmed
A case of Escherichia coli septicemia with associated metastatic en dophthalmitis and endocarditis is presented . - pubmed
Recently , three patients with acromegaly have been operated upon for active otologic disease . - pubmed
In 136 patients with cicatrical strictures of the esophagus the author performed total esophagoplasty , using the left colon ( 89 cases ) , the right colon with terminal iliac portion ( 8 cases ) , the small intestine by Roux - Herzen - Judin technic ( 27 cases ) and the small intestine with primary reconstruction of the graft ( 12 cases ) . - pubmed
Study of reticuloendothelial phagocytic capacity in patients with cholestasis . - pubmed
About half of the patients with cholestasis showed impaired Kupffer - cell phagocytosis . - pubmed
The finding may be relevant to the occurrence of surgical complications in patients with obstructive jaundice . - pubmed
The authors reviewed a series of 38 consecutive patients with trigeminal neuralgia treated by percutaneous thermocoagulation in 1984 - 90 . - pubmed
In patients in whom there was a sensory impairment after either thermocoagulation or other form of treatment ( injection of alcohol or rhizotomy ) repeated thermocoagulation not only did not give good results but could lead to worsening of the pain . - pubmed
Protection against benzo [ a ] pyrene- and N - nitrosodiethylamine - induced lung and forestomach tumorigenesis in A / J mice by water extracts of green tea and licorice . - pubmed
Atherogenic profiles in insulin - dependent diabetic patients and their treatment . - pubmed
Longitudinal studies have shown a large excess of cardiovascular mortality in insulin - dependent diabetic patients ( IDDM ) as compared to non - diabetic controls . - pubmed
xylosus and one strain of S. - pubmed
Relationship between redistribution on exercise thallium-201 scintigraphy and repetitive ventricular premature beats in patients with recent myocardial infarction . - pubmed
The relationship between myocardial ischemia detected by exercise thallium-201 scintigraphy and repetitive ventricular premature beats ( VPBs ) during ambulatory monitoring was evaluated in 57 patients with recent myocardial infarction . - pubmed
Thirty - five patients had redistribution , but only three of them had repetitive VPBs during exercise testing . - pubmed
Obesity and insulin resistance in humans : a dose - response study . - pubmed
Both in the basal state and following a hyperglycemic stimulus obese people display hyperinsulinemia , which correlates with the degree of insulin resistance . - pubmed
Considering that diabetic hypertensive patients are at high risk for atherosclerosis it appears also favourable that betaxolol did not increase triglyceride levels and even decreased total cholesterol . - pubmed
[ Effects of nimodipine on blood pressure and cardiac function in hypertensive patients ] . - pubmed
This double - blind randomized placebo - controlled study was designed to evaluate the acute effects of orally administered slow - release isosorbide-5 - mononitrate ( SR IS-5 - MN ) in 12 patients with chronic stable angina . - pubmed
Propranolol is likely to be widely used to prevent variceal haemorrhage in patients with cirrhosis . - pubmed
However , as long as the exact role of thiamine compounds in relation to membrane excitability in the nervous system remains unknown , it is impossible to conclude whether the differences observed in the metabolism of thiamine compounds are the cause or the consequence of the photosensitivity in the baboon Papio papio . - pubmed
Only four patients subsequently proved to have unequivocal chronic pancreatitis . - pubmed
There was no significant difference in the size or contour of the main pancreatic duct , or in side branch changes between those patients presenting with common bile duct stones , incidental biliary pathology and pain of probable pancreatic origin . - pubmed
We examined 21 patients with tumours of the mouth , one with tumour involvement of the facial skeleton and three with lymph node involvement in the upper neck , by nuclear tomography . - pubmed
Amongst our patients , nuclear tomography was also superior for showing lymph node metastases . - pubmed
Fluid resuscitation is complicated in hypotensive septic patients by their susceptibility to pulmonary edema . - pubmed
This problem was evaluated in the ovine model of endotoxemia with a chronic lung lymph fistula . - pubmed
Central penetrating excisional wounds were made in the corneas of 12 rabbits and 10 trout . - pubmed
The circadian pattern of intragastric acidity was assessed in 19 healthy subjects and 37 patients with active , endoscopically proven duodenal ulcer using 24 - hr continuous intraluminal pH - metry . - pubmed
The median pH 24 - hr profiles showed that ulcer patients had lower postprandial pH elevations and a smaller decline in acidity during the early morning hours when compared with controls . - pubmed
We conclude that the 24 - hr acidity is higher in ulcer patients compared to healthy subjects and that the differences are particularly evident in the postprandial and nocturnal periods . - pubmed
Those from SLE patients with active disease produced significantly more than did those from patients with inactive disease . - pubmed
Ventricular tachycardia could no longer be induced in 7 ( 35 % ) of the 20 patients studied with combination therapy . - pubmed
To prove the curve fitting to tumour growth by the modified logistic function the total number of Ehrlich ascites tumour cells was measured in 144 mice at 12 different times after inoculation . - pubmed
The abnormalities in conjugate eye movements observed after cerebellar lesions are related to the abnormalities in movements of the extremities observed in the same patients . - pubmed
[ Comparative evaluation of titrometric and colorimetric methods of determination of nonesterified fatty acids " NEFA " in the blood serum of diabetic patients ] . - pubmed
Influence of fluoride and phosphate on alveolar bone loss in the rat . - pubmed
[ Evaluation of the myelograms in acute leukemias in children treated at the District Special Hospital for Children in Opole during 1962 - 1964 ] . - pubmed
Cellular cytotoxicity of C57BL/6 adult mice peritoneal cells to xenogeneic ( Chang liver ) and syngeneic ( BL / 6 - WT3 ) herpes simplex virus ( HSV )- infected cells was analyzed in a 6 - h 51Cr release assay . - pubmed
There was no natural killer cytotoxicity to targets with cells from uninfected mice except at very high effector cell ratios . - pubmed
HSV - infected ( 2 X 10(4 ) PFU intraperitoneally 1 day previously ) mice mediated significantly higher antibody - dependent cellular cytotoxicity and required less antibody ( 10(-5 ) versus 10(-2 ) dilution ) , fewer cells , and less time to kill than cells from uninfected mice . - pubmed
HSV - infected mice mediated natural killer cytotoxicity but preferentially killed syngeneic HSV - infected cells . - pubmed
Stimulation of cytotoxicity was not virus specific since influenza - infected mice mediated similar levels of cytotoxicity to HSV - infected targets . - pubmed
The true diagnoses in the thirteen patients were : glioma in three ; meningioma , brain abscess , epilepsy and subdural haematoma in two patients each ; hepatic coma and syringobulbia in one patient each . - pubmed
Combined oral and nasal beclomethasone diproprionate in children with atopic eczema : a randomised controlled trial . - pubmed
In a double blind , placebo controlled , crossover trial in 26 children with severe atopic eczema those receiving four weeks ' treatment with combined oral plus nasal beclomethasone diproprionate improved significantly more than those receiving placebo . - pubmed
Of 12 adult patients with high - grade soft tissue sarcoma receiving adjuvant chemotherapy and at risk for 36 - 84 months , 9 ( 75 % ) remain metastasis free and 10 ( 83 % ) have adequate local disease control with limb preservation . - pubmed
Hypermetabolic doses of levothyroxine sodium produced remissions in five of seven women with intractable manic - depressive illness who were followed up for nine months to nine years . - pubmed
In hyperthyroid subjects , the serum levels of total and free cholesterol were significantly lower than in normal subjects and the fractional lecithin : cholesterol acyl transfer rate was significantly higher than in normal subjects . - pubmed
The free cholesterol / total cholesterol ratio in hypothyroid females and the serum levels of triglyceride and free fatty acid in hypothyroid male were significantly higher than in normal subjects . - pubmed
The fractional lecithin : cholesterol acyl transfer rates in hypothyroid females were significantly lower than in normal females . - pubmed
The dynamics of cell - mediated immunity indices in 83 patients with rectal tumors who underwent surgery or received combined treatment ( preoperative radiation + surgery ) was followed . - pubmed
METHODS : Thirty - three patients had localization of a solitary adenoma with 99mTc - sestamibi . - pubmed
A novel mycoplasmal species designated as Mycoplasma penetrans has been isolated recently from patients infected with human immunodeficiency virus . - pubmed
Dipole source analysis was carried out in three adults and four children with 3 c / s generalized spike - wave ( SW ) discharges and absence seizures . - pubmed
Bone marrow and peripheral blood lymphocyte phenotype in patients with bone marrow failure . - pubmed
However , the phenotype of immune effectors in the marrow of AA patients remains unknown . - pubmed
We examined severe ( sAA ) and moderate AA ( mAA ) patients and compared them to healthy volunteers and patients with myelodysplastic syndrome ( MDS ) . - pubmed
Helminthic infestation complicated by intussusception in baboons ( Papio hamadryas ) . - pubmed
This helminth is well - recognized as a cause of intussusception in human infants , but the complication has not been reported previously in non - human primates . - pubmed
Then , in two separate experiments , endotoxin - induced uveitis was produced in a total of 48 mice by injecting Salmonella typhimurium endotoxin into one hind footpad . - pubmed
Electron microscopic identification of parvovirus virions in erythroid and granulocytic - line cells in a patient with human parvovirus B19 induced pancytopenia . - pubmed
In this short report we describe a patient with human parvovirus B19 ( HPV B19)-induced transient pancytopenia . - pubmed
RESULTS : Patients requiring pedal bypass were more likely to have diabetes and congestive heart failure but less likely to have a history of smoking . - pubmed
Pedal bypass represented 21 % of our experience with infrapopliteal vein grafts for chronic limb - threatening ischemia and was required more frequently in diabetic patients . - pubmed
Immune response in mice infected with the attenuated Japanese encephalitis vaccine strain SA14 - 14 - 2 . - pubmed
A single immunization with SA(A ) significantly protected mice against lethal intracerebral ( ic ) challenge with the virulent SA(V ) strain . - pubmed
Two patients are here reported with metastatic MTC , who developed CS two years after the thyroid cancer was diagnosed . - pubmed
A review is also made of clinical and biochemical characteristics of cases with MTC associated with ectopic CS reported in the literature and it is concluded that the cortico - adrenal function in follow - up should be monitored in patients with this type of cancer . - pubmed
Acidic urine was also demonstrated in those dogs with B. - pubmed
Recognition of drug side effects is vital for optimal patient care , because early withdrawal of the offending agent and institution of appropriate treatment have the potential to significantly reduce the overall morbidity and mortality associated with the diagnosis of cancer . - pubmed
Zinc deficiency and the desaturation of linoleic acid in rats force - fed fat - free diets . - pubmed
Additionally , in zinc - deficient rats there were changes of ( n-6 ) PUFA levels typical for impaired delta 5 and delta 6 desaturation : linoleic acid and dihomo - gamma - linolenic acid were elevated ; arachidonic acid , docosatetraenoic acid , and docosapentaenoic were lowered by zinc deficiency . - pubmed
Therefore , the study shows that zinc deficiency impairs desaturation of linoleic acid in rats force - fed fat - free diets and therefore supports results from former convential zinc deficiency experiments suggesting a role of zinc for desaturation of linoleic acid . - pubmed
MATERIALS AND METHODS : Specific characterization and quantification of hemodynamic abnormalities of the cavernous arterial inflow and corporeal veno - occlusive mechanism associated with failure to respond to intracavernous pharmacotherapy were performed retrospectively in 69 patients with nonendocrinological impotence . - pubmed
PURPOSE : To determine the reliability and the measuring agreement between two radiologists in the identification of relevant structures of prostate anatomy in patients with prostate carcinoma . - pubmed
PATIENTS AND METHOD : 15 patients with prostate carcinoma proved by histology underwent MR Imaging on 1.5 Tesla MR - system ( Siemens Erlangen ) . - pubmed
The case of a 47 - year - old man surgically treated with Halsted mastectomy for breast cancer and submitted to Tamoxifen therapy for more than four years is reported . - pubmed
Topical delivery of keloid therapeutic drug , tranilast , by combined use of oleic acid and propylene glycol as a penetration enhancer : evaluation by skin microdialysis in rats . - pubmed
As with intervertebral disc herniation in children , an accurate diagnosis may be often delayed due to concerns for neoplasm , infection , and spondylolisthesis . - pubmed
Hepatocellular carcinoma ( HCC ) is the major primary malignant tumor in the human liver , but the molecular changes leading to liver cell transformation remain largely unknown . - pubmed
We then analyzed human HCCs and found similar mutations in eight of 31 ( 26 % ) human liver tumors tested and in HepG2 and HuH6 hepatoma cells . - pubmed
Intraarticular variability of synovial membrane histology , immunohistology , and cytokine mRNA expression in patients with rheumatoid arthritis . - pubmed
CONCLUSION : Biopsies from the suprapatellar pouch , medial gutter , and cartilage - pannus junction will provide a representative sample of synovial membrane pathology in patients with rheumatoid arthritis . - pubmed
Thrombotic microangiopathy in the HIV-2 - infected macaque . - pubmed
Thrombotic microangiopathy ( TMA ) has been increasingly reported in human immunodeficiency virus ( HIV )- infected humans over the past decade . - pubmed
We prospectively analyzed the renal pathology and function of 27 pigtailed macaques ( Macaca nemestrina ) , infected intravenously with a virulent HIV-2 strain , HIV-2(287 ) , in addition to that of four uninfected control macaques . - pubmed
Typical lesions of human HIV - associated nephropathy were undetectable . - pubmed
Six of the 27 HIV-2 - infected macaques demonstrated both histological TMA lesions ( thrombi in glomerular capillary loops and small arteries , mesangiolysis ) and ultrastructural lesions ( mesangiolysis , subendothelial lucency , platelet thrombi in glomerular capillary lumina ) . - pubmed
Extrarenal thrombi were detected in the gastrointestinal and adrenal microvasculature of macaques that had developed renal TMA . - pubmed
In a retrospective analysis of kidneys obtained from 39 additional macaques infected with HIV-2(287 ) , seven cases demonstrated TMA . - pubmed
In situ hybridization showed no detectable HIV-2 RNA in kidney sections of 65/66 HIV-2 - infected macaques , including all 13 TMA cases . - pubmed
The HIV-2 - infected macaque may be a useful model of human HIV - associated TMA . - pubmed
[ Ampli - pulse phoresis in patients with partial optic nerve atrophy ] . - pubmed
This assay would permit discrimination between those animals naturally infected with wild type BHV1 and those vaccinated with tk - BHV1 strains . - pubmed
In spite of this , analysis of postoperative complications , line loss of the preoperative best spectacle corrected acuity and patients satistaction shows that LASIK is a better method in correction of high myopia by excimer laser . - pubmed
Perinephric abscess due to Aspergillus fumigatus . - pubmed
Biventricular pacing has been proposed to resynchronize ventricular contraction in patients with congestive heart failure ( CHF ) and interventricular conduction delay . - pubmed
A total of 15 patients ( 52 % ) had ICD shocks and 6 patients ( 21 % ) had 113 episodes of ventricular tachyarrhythmias , of which 96 ( 85 % ) were converted to sinus rhythm with antitachypacing . - pubmed
Thus , ischemic patients with reduced left ventricular ejection fraction and ventricular tachyarrhythmias seem good candidates for biventricular pacing with ICD backup . - pubmed
The sudden death risk for those with idiopathic dilated cardiomyopathy , however , is difficult to stratify , and the choice of ICD backup has to be considered on the basis of patient safety , as well as of costs . - pubmed
Gene therapy of Parkinson ' s disease using adeno - associated virus ( AAV ) vectors . - pubmed
Onychomycosis due to Candida parapsilosis . - pubmed
We report a case of onychomycosis with melanonychia due to Candida parapsilosis alone . - pubmed
Candida parapsilosis is now identified in the great majority of candidal onychomycosis , mainly in association with other yeasts . - pubmed
We present a case of intramedullary spinal gangliocytoma in a 7 - year - old girl who presented with scoliosis and progressive weakness of both legs . - pubmed
EXEGESIS : We report four patients with Hashimoto ' s thyroiditis who presented neurological or psychiatric features . - pubmed
Cross - sectional studies involved parasitological examination and anaemia evaluation before and at 10 months and 15 months after schoolchildren were dewormed . - pubmed
Attributable fraction analysis suggested that hookworm and schistosomiasis were responsible for 6 % and 15 % of anaemia cases , respectively . - pubmed
The complex pathophysiology of chronic kidney disease alters the adaptations to anaemia in uraemic patients . - pubmed
The increased cardiac output induced by anaemia is associated with left ventricular hypertrophy and cardiac disease in renal patients . - pubmed
A total of 42 patients with suspected CAD were studied . - pubmed
Significant coronary narrowing ( & gt ; or = 50 % luminal stenosis ) was detected by angiography in 22 patients . - pubmed
At visual analysis , all patients with CAD ( & gt ; or = 50 % luminal stenosis ) ( n-22 ) had an abnormal 99mTc tetrofosmin tomogram . - pubmed
Nine out of 20 patients without significant coronary narrowing ( but with tortuosis , atheromathosis , with microvascular diseases ) showed abnormal findings . - pubmed
Catecholamine levels in peripheral blood lymphocytes from multiple sclerosis patients . - pubmed
We studied peripheral blood lymphocytes from MS patients . - pubmed
The levels of dopamine ( DA ) , norepinephrine ( NE ) , epinephrine ( E ) and their metabolites in extracts of lymphocytes from 58 MS patients and 19 healthy controls were measured by using capillary electrophoresis . - pubmed
The MS patients were divided into clinical subgroups : a laboratory - supported definitive ( first - attack ) MS group , and a relapsing - remitting ( RR ) group in remission . - pubmed
The peripheral blood lymphocyte level of epinephrine was significantly higher in the first - attack MS patients ( p=0.028 ) than in the controls . - pubmed
Local delivery of nitric oxide from an eluting stent to inhibit neointimal thickening in a porcine coronary injury model . - pubmed
Morphometric analyses were performed in 16 pigs to determine the effect of NO - eluting stents on neointimal hyperplasia 28 days following arterial injury . - pubmed
Although local delivery of NO from this device did not reduce neointimal hyperplasia in this porcine model , this polymer - coated stent might be a promising tool for administration of other agents that may modify the reparative tissue responses leading to restenosis . - pubmed
There were no intraoperative complications and no conversions , and postoperatively all patients were started on a clear liquid diet on postoperative day 1 . - pubmed
Four patients were pain free , whereas one patient required intermittent narcotics at 1 - year follow - up . - pubmed
[ Opportunistic infections in HIV - positive patients hospitalized in the Clinic of Infectious Diseases AMG ] . - pubmed
Effects of Melilotus officinalis on acute inflammation . - pubmed
Our study investigated the effects of Melilotus officinalis L. extract , containing 0.25 % coumarin , on acute inflammation induced with oil of turpentine in male rabbits . - pubmed
In the bone marrow acute phase response , M. - pubmed
OBJECTIVE : To evaluate the outcome of using radiotherapy ( RT ) alone to treat patients with early - stage Hodgkin ' s disease ( HD ) . - pubmed
METHOD : The records of 28 patients with HD treated with RT alone at Kuwait Cancer Control Center between 1980 and 1998 were reviewed . - pubmed
Two patients had B symptoms , 12 ( 42.9 % ) patients lymphocyte - predominant histology , 9 ( 32.1 % ) nodular sclerosis and 7 ( 25 % ) mixed cellularity . - pubmed
PURPOSES : To retrospectively determine the factors influencing treatment decisions in older breast cancer patients at a single center . - pubmed
EXPERIMENTAL DESIGN : 216 patients age & gt ; or = 75 seen in post - treatment follow - up between January , 1997 and June , 2000 were identified in the Memorial Sloan - Kettering breast cancer database . - pubmed
CONCLUSION : We hypothesize that both comorbidity and age play a significant role in influencing treatment decisions in the older breast cancer patient but these two variables are not necessarily correlated . - pubmed
Postoperative complications due to Staphylococcus aureus . - pubmed
Optical mapping of the spread of excitation in the isolated rat atrium during tachycardia - like excitation . - pubmed
We aimed to assess transmissibility of the bovine spongiform encephalopathy ( BSE ) agent to primates by the intravenous route and study its tissue distribution compared with infection by the oral route . - pubmed
Human iatrogenic vCJD cases infected intravenously raise the same public - health concerns as primary cases and need the same precautionary measures with respect to blood and tissue donations and surgical procedures . - pubmed
Participants included five people without any neuromuscular impairment . - pubmed
Our study was undertaken to investigate whether bacterial endotoxin / lipopolysaccharide ( LPS ) affects the neurogenic vasopressor response in rats in vivo by presynaptic mechanisms and , if so , to characterize the type of presynaptic receptor(s ) operating in the initial phase of septic shock . - pubmed
Twelve intramuscular injections in six weeks led to significantly more participants with a good overall therapeutic effect after one year , and to significantly better pain reduction during one of two activities . - pubmed
One trial ( 43 participants ) found that intramuscular injections of the anabolic steroid nandrolone phenylpropionate significantly improved both pain and function compared to placebo injections . - pubmed
The criterion of qualification for the investigated group was medical history of a patient , which revealed climacteric symptoms and age of women ( from 45 to 60 years old ) . - pubmed
[ Results evaluation of surgical treatment of patients with lower eyelid defects ] . - pubmed
METHODS : Fifty - eight elderly individuals were tested for delayed - type hypersensitivity ( DTH ) responses to Candida and tetanus antigens . - pubmed
CONCLUSIONS : An inverse relationship between Candida DTH response and CIRS score suggests that increased chronic disease burden is associated with diminished cell - mediated immune response . - pubmed
A 22 - year - old Caucasian patient underwent living - donor liver transplantation ( LDLT ) for hepatic hemangioendothelioma in a healthy liver . - pubmed
MATERIAL AND METHODS : The vascular systems of seven edentulous human cadavers were flushed out and filled with either red - colored rubber bond or Indian ink and formalin mixture . - pubmed
INTRODUCTION : Hepatitis C virus ( HCV ) has been implicated as a risk factor for the development of diabetes mellitus , type 2 ( DM2 ) . - pubmed
RESULTS : We found 13 % of diabetics in the patient with viral RNA , 9.3 % in the infected patients without RNA and 3.9 % in the controls . - pubmed
The presence of HCV - antibodies showed a 2.78 odds ratio for diabetes risk . - pubmed
DISCUSSION : Our results showed a relationship between HCV infection and diabetes mellitus type 2 , so that the percentage of diabetics increased parallelly with the degree of viral activity and the variable " presence of HCV - antibodies " was the one that most contributed to the risk . - pubmed
Although our results would support the role of the iron metabolism in the development of diabetes , follow - up studies of a cohort of patients infected by HCV would be necessary to contrast this statement . - pubmed
The treatment of obesity in companion animals frequently focuses on restriction of energy intake . - pubmed
Musicogenic seizures can arise from multiple temporal lobe foci : intracranial EEG analyses of three patients . - pubmed
The ictal - onset zones in these patients were then further localized using by intracranial EEG monitoring , and the outcomes of the two patients who underwent epilepsy surgery were determined . - pubmed
RESULTS : Patient 1 's musicogenic seizures localized to the right lateral temporal lobe , patient 2 's originated in the right mesial temporal lobe , and patient 3 's arose independently from both mesial temporal lobes . - pubmed
Patients 1 and 2 underwent resective epilepsy surgery and are seizure free ( Engel class I ) . - pubmed
Patients with medically intractable musicogenic epilepsy and with unilateral ictal onset zones may be considered candidates for resective epilepsy surgery . - pubmed
Twenty - two subjects were examined in normoxia ( 21 % O2 ) , after 16 hours passive exposure to normobaric hypoxia ( 12 % O2 ) corresponding to a simulated altitude of 4,500 m and after 6 hours recovery in normoxia . - pubmed
Clinical AMS was diagnosed in 50 % of subjects during hypoxia and corresponding headache scores were markedly elevated ( P<0.05 versus non - AMS ) . - pubmed
All treatments currently approved for AD have moderate efficacy in slowing the rate of cognitive decline in patients , and no efficacy in halting progression of the disease . - pubmed
After long - term therapy , some patients with systolic heart failure ( HF ) display improved left ventricular ( LV ) function over time , a response that is associated with improved long - term outcomes . - pubmed
To investigate predictors of improved LV function in an ethnically diverse HF cohort , we selected 71 patients with HF who had baseline ejection fractions ( EF ) & lt;40 % , follow - up EFs & gt ; or = 50 % , and & gt;20 % increases on follow - up echocardiography performed & gt ; or = 6 months later . - pubmed
In conclusion , patients with hypertensive causes of HF are more likely to demonstrate improved LV function over time than patients with ischemic causes of HF . - pubmed
RESULTS : The biopsy results were normal in 78 patients , scant atypical and malignant cells in 30 , carcinoma with treatment effect in 43 , and carcinoma without treatment effect in 13 . - pubmed
Anti - ulcer activity of Adhatoda vasica Nees . - pubmed
Adhatoda vasica Nees ( Acantheceae ) , commonly known as Vasaka , is a well - known plant in indigenous systems of medicine and is used for its beneficial effects , particularly in bronchitis . - pubmed
The present investigation was carried out to study the anti - ulcer activity of Adhatoda vasica leaves using two ulcer models ( 1 ) Ethanol - induced , and ( 2 ) Pylorus ligation plus aspirin - induced models . - pubmed
Adhatoda vasica leaf powder showeda considerable degree of anti - ulcer activity in experimental rats when compared with a control . - pubmed
Results of the study suggest that in addition to its classically established pharmacological activities , the plant also has immense potential as an anti - ulcer agent of great therapeutic relevance . - pubmed
Plasmablastic cytomorphologic features in plasma cell neoplasms in immunocompetent patients are significantly associated with EBV . - pubmed
Multiple myeloma ( MM ) is rarely associated with Epstein - Barr virus ( EBV ) irrespective of HIV status , in contrast with its morphologic mimic , plasmablastic lymphoma , which occurs mainly in immunocompromised patients with frequent EBV association . - pubmed
The patient with plasmacytoma was disease free for 75 months , and the remaining 3 patients with MM died at 15 , 74 , and 97 months , respectively ; the median survival of patients with EBER - MM was 12 months . - pubmed
EBV+ tumors were associated with plasmablastic cytomorphologic features and high labeling indices . - pubmed
These tumors may have been driven by EBV to gain the plasmablastic cytomorphologic features and high proliferation fraction . - pubmed
A large cohort study is needed to clarify the prognostic impact of EBV on immunocompetent patients with MM . - pubmed
CONCLUSIONS : Contrast - enhanced CT scanning results in superior diagnostic precision in patients with acute abdominal pain . - pubmed
Finally , we demonstrate an inverse relationship between AS and gene duplication , suggesting that the latter may be primarily responsible for the emergence of new functional transcripts in nematodes . - pubmed
No inverse hypopyon was observed in any of patients . - pubmed
CONCLUSIONS : Silicone oil emulsification may develop earlier than expected in patients with nystagmus who underwent pars plana vitrectomy combined with silicone oil injection . - pubmed
Prenatal choline supplementation attenuates neuropathological response to status epilepticus in the adult rat hippocampus . - pubmed
Prenatal choline supplementation ( SUP ) protects adult rats against spatial memory deficits observed after excitotoxin - induced status epilepticus ( SE ) . - pubmed
To determine whether the tyrc allele was directly responsible for the response to selection , we examined B6 mice that have a mutant tyr allele ( tyr(c-2j- ) ) and an AJ congenic strain that has the wild - type B6 allele for tyr . - pubmed
Multigenic factors associated with a hydrocephalus - like phenotype found in inter - subspecific consomic mouse strains . - pubmed
Hydrocephalus is a significant clinical condition in humans and is known to be a multifactorial neurologic disorder . - pubmed
By analyzing breeding records of a panel of inter - subspecific consomic mouse strains , we found that consomic strains with MSM / Ms ( MSM ) chromosomes 4 , 5 , 7 , 11 , 15 , and 17 showed a significantly higher incidence of hydrocephalus , whereas both parental strains , MSM and C57BL/6J ( B6 ) , rarely showed this abnormality . - pubmed
Of these , post - stroke hyperglycaemia ( PSH ) is the most frequently recognised abnormality and is documented in up to 50 % of patients at the time of stroke presentation . - pubmed
Importantly , a significant proportion of hyperglycaemic acute stroke patients ( approximately 50 % ) have undiagnosed disorders of glucose metabolism , including diabetes . - pubmed
Animal and human data have repeatedly demonstrated that PSH negatively impacts upon the fate of ischaemic brain tissue , with greater infarct growth , higher mortality and more severe disability being consistent findings amongst hyperglycaemic stroke subjects . - pubmed
The airway NO flux and alveolar NO concentration can be elevated in adults and children with asthma and have been correlated with markers of airway inflammation and airflow obstruction in cross - sectional studies . - pubmed
Number of studies have shown a high prevalence of patent foramen ovale ( PFO ) in patients with migraine , especially migraine with aura . - pubmed
Furthermore patients with PFO and migraine also show a marked improvement in their symptoms after percutaneous closure of the PFO . - pubmed
We clinically evaluated seven individuals with HGPPS from five previously unreported consanguineous families . - pubmed
All affected individuals had severe horizontal gaze restriction , progressive scoliosis , and lower brainstem hypoplasia on neuroimaging , the hallmarks of this syndrome . - pubmed
One individual experienced head trauma with a right subdural hematoma associated with a right hemiparesis , observations that confirm clinically for the first time that corticospinal tracts in HGPPS are uncrossed . - pubmed
METHODS : 513 APL patients in the last two decades were retrospectively analyzed in this research . - pubmed
RESULTS : The median age of the APL patients was 33 years old and the ratio of male and female was 1.21:1 . - pubmed
CONCLUSIONS : Comprehensive evaluation of MICM could be of important significance in the diagnosis and prognosis judgment for APL patients . - pubmed
Over a period of 18 years , 17 patients with proven Langerhans cell histiocytosis ( LCH ) were treated at the Haematological Clinic in Brno . - pubmed
In 13 of them , the disease was diagnosed at adult age , and 4 patients were referred to the centre with LCH diagnosed at early child age . - pubmed
One of these 4 patients suffered from repeated recurrences of the disease at adult age and was diagnosed with progressive neurodegenerative damage of the CNS at the age of 25 which in its terminal phase resulted in the patient 's immobility , loss of sphincter control , incapacity to communicate and death at the age of 32 . - pubmed
LCH was diagnosed at adult age in 13 patients . - pubmed
Only 2 of 13 patients ( 15 % ) had multiple bone lesions upon diagnosis , the remaining 6 patients ( 46 % ) had only one lesion at the time of diagnosis . - pubmed
Repeated recurrence of bone involvement was only recorded in 3 out of 13 patients ( 23 % ) . - pubmed
The combination of recurrent bone involvement and the development of lung affection ( dyspnoea , irritating cough , nodularities and cysts in HRCT images ) were documented in 2 out of 13 patients ( 15 % ) . - pubmed
One of the patients diagnosed with LCH at the age of37 had repeated recurrence of bone involvement , which was also treated by 2 cycles of high - dose chemotherapy and autologous transplantation . - pubmed
Primary extraoseal ( extamedular ) involvement was diagnosed in 5 out of 13 patients ( 38 % ) ( mandibular gum infiltration , single cervical node infiltration , hand skin infiltration , infiltration of the perineal region and infiltration of the hypophysial infundibular and primary lung form of LCH ) . - pubmed
In the 3rd case , the first sign ofthe disease was diabetes insipidus in a 34 - year - old man , and an infiltrate in the anal region similar to condylomata acuminata . - pubmed
LCH pulmonary involvement should be considered in patients with an interstitial pulmonary process and the examinations should be focused accordingly ( thoracoscopy with sampling for histological exams or bronchoalveolar lavage ) plus the indispensable immunohistochemical examination . - pubmed
Mounting evidence from clinical and basic research suggests that estrogen signaling may be altered in the brains of people with schizophrenia . - pubmed
338 patients with probable AD were treated with ChEis ( donepezil , rivastigmine and galantamine ) as per the clinician 's judgment and were observed for nine months . - pubmed
Patients were grouped in three different categories ( patients not depressed and not treated with SSRIs , patients depressed and treated with SSRIs , and patients depressed but not treated with SSRIs ) . - pubmed
The mean change in MMSE score from baseline to nine months showed that depressed patients not treated worsened in comparison with those not depressed and not treated with SSRIs ( mean change -0.8 + /- 2.3 vs 0.04 + /- 2.9 ; p = 0.02 ) and patients depressed and treated with SSRI ( mean change -0.8 + /- 2.3 vs 0.1 + /- 2.5 ; p = 0.03 ) . - pubmed
CONCLUSIONS : In AD patients treated with AChEIs , SSRIs may exert some degree of protection against the negative effects of depression on cognition . - pubmed
Adalimumab for psoriasis patients who are non - responders to etanercept : open - label prospective evaluation . - pubmed
OBJECTIVES : To assess the efficacy and safety of adalimumab ( 40 mg weekly ) in psoriasis patients who were non - responders to high - dosage etanercept ( 50 mg twice weekly ) . - pubmed
METHODS : All patients attending a tertiary referral service for severe psoriasis who were non - responders to high - dosage etanercept [ i.e. - pubmed
CONCLUSIONS : Initial data from this open - label prospective evaluation suggests that weekly adalimumab therapy is an effective treatment for patients with severe psoriasis who had failed to respond to at least 3 months of high - dosage etanercept . - pubmed
METHODS : Thirty - eight end - stage chagasic achalasia patients submitted to esophagectomy and cervical gastric pull - up were followed prospectively for a mean of 13.6 + /- 9.2 years . - pubmed
Results from pivotal registration trials in major depressive disorder cohere with outcomes from effectiveness studies indicating that the majority of individuals receiving single - agent pharmacotherapy fail to achieve and sustain symptomatic remission . - pubmed
The data from the studies reviewed herein also indicate that quetiapine XR poses a low risk for extrapyramidal side effects in middle - aged and elderly individuals with major depressive disorder . - pubmed
These recommendations were challenged recently by results of the Perioperative Ischemic Evaluation ( POISE ) , a large randomized trial of extended - release metoprolol succinate started immediately before noncardiac surgery in patients at high risk for atherosclerotic disease . - pubmed
The diagnosis of this disease can be performed through ultrasounds , but the molecular diagnosis offers some advantages , such as the early detection of asymptomatic individuals who carry this genetic defect , in order to perform a preventive monitoring and genetic counselling . - pubmed
In this work , we present the results of the clinical analysis of 48 patients diagnosed with autosomal dominant polycystic kidney disease . - pubmed
The arterial hypertension was the most frequent clinical manifestation of the disease in our study by what this entity should be included in all the hypertense patients of unknown etiology and on the other hand , the infectious complications should be a sign of alert in every patient with polycystic kidney disease . - pubmed
Use of computed tomography for cervical spine clearance in trauma patients . - pubmed
The need exists to strengthen the capacity of religious congregations to teach about HIV / AIDS and target non - religious youth with HIV transmission and prevention information . - pubmed
Anti-(+)-methamphetamine monoclonal antibody antagonists designed to prevent the progression of human diseases of addiction . - pubmed
Clinical trials of reperfusion therapies for acute ischemic stroke patients in an extended time window have shown mixed results . - pubmed
OBJECTIVES : The aim of this study is to investigate the presence and the features of ToM decay in early Alzheimer ' s disease ( AD ) patients compared to healthy controls adopting a neurodevelopmental stance . - pubmed
METHOD : Sixteen AD patients and 16 healthy controls were submitted to an increasing complexity ToM battery , tapping ToM precursors , standard first- and second - order false beliefs and advanced ToM tasks ( Eyes Test and strange stories ) . - pubmed
CONCLUSION : This study identifies a specific pattern of deterioration in ToM abilities in AD patients , following backwards developmental steps typical of the acquisition of mentalizing abilities , where the most complex ToM levels are impaired , whereas the intermediate and the simplest ones are preserved . - pubmed
We detail the clinical course of a patient with peripheral vascular disease and indwelling superficial femoral artery stent , who developed stent thrombosis in the 2 - week period between his last clinic visit and date of surgery , with no change in symptoms . - pubmed
Based on intravascular ultrasound findings , it appears that coronary artery spasm promotes negative arterial remodeling , suggesting that patients with coronary artery spasm might be at higher risk of accelerated coronary atherosclerosis . - pubmed
We report the cases of 3 patients with ventricular arrhythmia secondary to coronary artery spasm complicated by accelerated coronary atherosclerosis . - pubmed
Consequently , coronary disease progression should be considered in the case of angina pectoris recurrence in patients with coronary artery spasm , especially in those with coronary artery spasm complicated by ventricular arrhythmia . - pubmed
A total of 25 patients had a history of CAD ( 15 % ) . - pubmed
The CCA diameters of patients with CAD were significantly higher than those of patients without CAD ( 7.9 + /- 1.0 mm and 7.4 + /- 0.9 mm ; p = 0.01 ) . - pubmed
Receiver operating characteristic curve of boundary value of CCA diameter revealed an area under the curve to identify the patients with CAD ( 0.63 , p = 0.04 ) . - pubmed
As free - living Gerbillus nanus show a relatively low flea infestation , we hypothesized that this host uses an induced strategy and , consequently , flea infestation would not impose a long - term effect on energy metabolism . - pubmed
Thus , the hypothesis that flea infestation does not have a long - term effect on energy metabolism was supported , as was the idea of an induced over a constitutive immune response by G. - pubmed
Thus , aspirin prodrugs effectively inhibit human platelet aggregation and as such may be an alternative to conventional aspirin . - pubmed
In this paper , we will review the current knowledge about familiality of LPL / WM and provide novel data on solid tumors and myeloid malignancies in first - degree relatives of LPL / WM patients . - pubmed
A number of bioactive compounds generally obtained from terrestrial plants such as isoflavones , diosgenin , resveratrol , quercetin , catechin , sulforaphane , tocotrienols and carotenoids are proven to reduce the risk of cardiovascular diseases and aid in cardioprotection which is the leading cause of death globally . - pubmed
UNLABELLED : The study was aimed to evaluate microvascular blood flow and theological blood properties in healthy volunteers ( n = 27 ) and patients with cerebral accident ( n = 30 ) . - pubmed
Thus , our results demonstrated the decrease of tissue perfusion , activization of vasodilating mechanisms , impaired blood rheology and the decrease of oxygen supply to tissue in patients with cerebrovascular accident . - pubmed
Annato extract and beta - carotene modulate the production of reactive oxygen species / nitric oxide in neutrophils from diabetic rats . - pubmed
The present study was undertaken to evaluate the possible protective effects of annatto on the reactive oxygen species and nitric oxide ( NO ) inhibition in neutrophils from alloxan - induced diabetic rats . - pubmed
Our results show that neutrophils from diabetic animals produce significantly more reactive oxygen species and NO than their respective controls and that supplementation with beta carotene and annatto is able to modulate the production of these species . - pubmed
We describe here an unusual occurrence of pseudoaneurysms in the common carotid and vertebral artery in a four - year - old child victim of a stab wound in the neck treated by parent artery occlusion of the vertebral and common carotid arteries . - pubmed
Individualized care for improved outcomes in patients with atrial fibrillation . - pubmed
METHODS : Rheumatoid arthritis ( RA ) patients who had taken CQ for at least 6 months and stable CQ dosage for at least 2 months were included . - pubmed
In DU145 tumor bearing mice , a single treatment of tumor hyperthermia , induced via gold nanorod mediated plasmonic photothermal therapy , and intravenous administration of HSP targeted HPMA copolymer - docetaxel at 10mg / kg resulted in maintained tumor regression for a period of 30 days . - pubmed
Prevalence of Pulmonary Tuberculosis Among HIV Positive Patients Attending Antiretroviral Therapy Clinic . - pubmed
RESULTS : This study showed 1012/172 ( 17 % ) prevalence of pulmonary tuberculosis among HIV positive patients , of which 87 ( 50.58 % ) were males and 85 ( 48.42 % ) were females . - pubmed
CONCLUSION : The study showed that 17 % of HIV infected persons had tuberculosis co - infection . - pubmed
The infection biology of Mycobacterium avium subsp . - pubmed
The prognosis is poor in patients with positive resection margins , high - grade tumours and recurrent tumours . - pubmed
Transfusion of platelets treated ex vivo with MG132 and washed before transfusion into thrombocytopenic mice also reduced carotid artery thrombosis . - pubmed
Clumps of regenerants , from cotyledons and hypocotyls ofPelargonium X hortorum seedlings , were inoculated with the disarmed strain EHA101 ofAgrobacterium tumefaciens . - pubmed
Evaluation of cerebrovascular reserve using xenon - enhanced CT scanning in patients with symptomatic middle cerebral artery stenosis . - pubmed
Cerebrovascular reserve ( CVR ) is an important prognostic factor in patients with major cerebral arterial steno - occlusive disease . - pubmed
Twelve patients with symptomatic MCA stenosis were recruited . - pubmed
Impaired CVR is an important characteristic of patients with symptomatic MCA stenosis . - pubmed
We demonstrate that reduction of spliceosomal activity through loss of peanuts promotes decondensation defects in NC nuclei during mid - oogenesis . - pubmed
Study of pharmacodynamic interaction of Phyllanthus emblica extract with clopidogrel and ecosprin in patients with type II diabetes mellitus . - pubmed
The effect of vitamin C on platelet aggregation in healthy and coronary artery disease patients has been demonstrated . - pubmed
MATERIALS AND METHODS : This was a randomized open label crossover study of 10 type II diabetic patients . - pubmed
Further , the mean percent inhibition of platelet aggregation was significant , when compared between single and multiple doses of P. - pubmed
The fusion protein showed very low toxicity in mouse experiments and impressive antitumor effects in a Lewis Lung carcinoma model , with a 90 % cure rate . - pubmed
Chronic pancreatitis and systemic inflammatory response syndrome prevent impact of chemotherapy with gemcitabine in a genetically engineered mouse model of pancreatic cancer . - pubmed
BACKGROUND AND AIMS : BACKGROUND AND AIMSGemcitabine is the standard therapy for patients with pancreatic cancer with metastatic disease . - pubmed
Genotoxic effects of commercial formulations of Chlorpyrifos and Tebuconazole on green algae . - pubmed
The alkaline single - cell gel electrophoresis assay ( comet assay ) was used for the study of the genotoxic effects of insecticide Chlorpyrifos and fungicide Tebuconazole ( commercial formulations ) on two freshwater green algae species , Pseudokirchneriella subcapitata and Nannocloris oculata , after 24 h of exposure . - pubmed
Cardiovascular magnetic resonance using oedema and fibrosis imaging can early reveal , noninvasively and without radiation , heart involvement during vasculitis , undetected by other imaging techniques and guide further risk stratification and treatment of these patients . - pubmed
Evaluation of early response to hepatic arterial infusion chemotherapy in patients with advanced hepatocellular carcinoma using the combination of response evaluation criteria in solid tumors and tumor markers . - pubmed
METHODS : One hundred sixty - five HCC patients treated with HAIC were reviewed retrospectively . - pubmed
CONCLUSION : The use of the combination of RECIST and tumor marker ratio could be useful for assessment of the early response to HAIC and prognosis of patients with advanced HCC . - pubmed
We studied all patients having a surgical revision in our center for a severe bleb leak between January 1 and December 31 , 2008 . - pubmed
In comparing the risk for a severe bleb leak in younger ( below 55 y ) versus patients aged 75 years or older , the odds ratio was 21.0 . - pubmed
A trend was observed in which the patients under the age of 55 years were at greater risk for a severe bleb leak . - pubmed
Human cervical cancer xenografts were established in nude mice by transplantation of HeLa cells , and the tumors were then treated with psPEF . - pubmed
This view has been called into question by the unexpected results of the Human Genome Project which has painted a far more complex picture of the genetic features of human disease than was anticipated . - pubmed
The case of a 25 - year - old female patient with stage IV lung adenocarcinoma who developed fatal ILD is reported here . - pubmed
One month after treatment initiation , the patient complained of continuous dry cough and rapid progressive dyspnea . - pubmed
Forty one days after icotinib treatment , icotinib associated ILD was suspected when the patient became increasingly dyspnoeic despite of treatment of pericardial effusion , left pleural effusion and lower respiratory tract infection , and X - ray computed tomography ( CT ) of chest revealed multiple effusion shadows and ground - glass opacities in bilateral lungs . - pubmed
Forty three days after icotinib treatment , the patient died of hypoxic respiratory failure . - pubmed
To establish vascular restenosis , rat carotid arteries were subjected to balloon angioplasty injury . - pubmed
BACKGROUND : The Collaborative Cross ( CC ) is a large panel of genetically diverse recombinant inbred mouse strains specifically designed to provide a systems genetics resource for the study of complex traits . - pubmed
This report is also the first to establish guidelines in defining and identifying strain - specific splicing across different mouse strains . - pubmed
METHODS : This is a retrospective study of 460 systemic lupus erythematosus patients followed in a single rheumatologic center during the last 10 years . - pubmed
Patients with lymphopenia had more leukopenia ( OR=1.8 ; 95 % CI=1.01 - 3.29 ) and lupus anticoagulant antibodies ( OR=2.2 ; 95 % CI=1.16 - 4.39 ) and those with thrombocytopenia had more leukopenia ( OR=3.1 ; 95 % CI=1.82 - 5.44 ) and antiphospholipid syndrome ( OR=3.1 ; 95 % CI=1.28 - 7.87 ) . - pubmed
Hepatic Lesions Caused by Large Granular Lymphocyte Leukemia in Fischer 344 Rats : Similar Morphologic Features and Morphogenesis to Those of Nodular Regenerative Hyperplasia ( NRH ) in the Human Liver . - pubmed
To characterize the hepatic lesions in Fischer 344 ( F344 ) rats afflicted with large granular lymphocyte ( LGL ) leukemia , the livers of rats with LGL leukemia at various stages were examined histopathologically and immunohistochemically . - pubmed
The morphologic features in the livers of rats afflicted with LGL leukemia were diffuse , uniform - sized , granular , or micronodular lesions consisting of hepatocytes showing centrilobular atrophy and perilobular hypertrophy ( CAPH ) without fibrosis . - pubmed
With progression in the stage of the LGL leukemia , the severity of the CAPH of hepatocytes increased resulting in fatty change and/or single - cell necrosis , along with compensatory hyperplasia of the hepatocytes , finally resulting in lesions similar to those seen in nodular regenerative hyperplasia ( NRH ) in the human liver . - pubmed
In addition , direct and/or indirect hepatocellular injuries by leukemia cells were considered to be necessary for the formation of human NRH - like lesions . - pubmed
Morphogenetic investigation of the livers of rats afflicted with LGL leukemia may be helpful to clarify the pathogenesis of NRH in the human liver . - pubmed
Dental caries is a widely prevalent infectious disease afflicting the humans worldwide . - pubmed
However availability of review articles regarding triphala as an antimicrobial against oral infections is limited . - pubmed
The present article reviews the use of triphala and its constituents in the prevention and control of dental caries and other common oral infections . - pubmed
Thorough review of the literature indicated that triphala can be effectively used to manage dental caries , gingival and periodontal diseases . - pubmed
CASE PRESENTATION : A 54 - year - old Chinese woman with a history of diffuse large B - cell lymphoma in her first complete remission developed peripheral neuropathy and tracheal asphyxia . - pubmed
We examined patients with incidental hemangiomas who received anti - angiogenic agents for the treatment of other malignancies . - pubmed
Our study population consisted of 17 colorectal cancer patients and one lung cancer patient carrying 21 hemangiomas who received bevacizumab , and seven renal cell carcinoma patients carrying nine hepatic hemangiomas who received sunitinib . - pubmed
METHODS : The study enrolled 44 prepubertal children ( between 2 and 12 years of age ) with thinness grades of 1 - 3 and 41 healthy age- and gender - matched children . - pubmed
Aortic rupture after thoracic endovascular repair in a patient with familial thoracic aortic aneurysm and dissections type 6 ( FTAAD6 ) . - pubmed
CONCLUSIONS : Lower WM integrity in MMT patients may add to neurobiological factors associated with relapse to heroin use . - pubmed
OBJECTIVE : Determine the effectiveness of in vitro maturation of oocytes in the infertility treatment in high altitude women with polycystic ovaries . - pubmed
PARTICIPANTS : Women with polycystic ovaries and infertility . - pubmed
INTERVENTIONS : there were 11 women from locations above 7,546 feet above sea level with polycystic ovaries and infertility in which were performed in vitro maturation of oocytes , followed by intracytoplasmic sperm injection , culture and embryo vitrification . - pubmed
CONCLUSIONS : In vitro maturation of oocytes is an effective technique in the infertility treatment of high altitude women with polycystic ovaries . - pubmed
METHODS : In this prospective study , 60 patients ( of either sex ) with chronic suppurative otitis media inactive mucosal disease were divided into 2 groups ( 30 in each ): group A comprised paediatric patients aged 5 - 8 years and group B consisted of older individuals aged over 14 years . - pubmed
Focus on the prophylaxis , epidemiology and therapy of methicillin - resistant Staphylococcus aureus surgical site infections and a position paper on associated risk factors : the perspective of an Italian group of surgeons . - pubmed
We report the case of a 47 - year - old woman whose primary mediastinal leiomyoma was incidentally found during evaluation of her persistent cough . - pubmed
This is a prospective cohort study of 7,216 patients with clinically manifest arterial disease in the Secondary Manifestations of Arterial Disease Study . - pubmed
spinosa Co121 increased 77.13 % , from 310.44 + - 21.84 mug / mL in the initial fermentation medium ( with glucose as the main carbon source ) to 549.89 + - 38.59 mug / mL in a new optimized fermentation medium ( 98.0 g of mannitol , 43.0 g of cottonseed flour , 12.9 g of corn steep liquor , 0.5 g of KH2PO4 , and 3.0 g of CaCO3 in 1 L of H2O ; pH was adjusted to 7.0 before autoclaving ) . - pubmed
CONCLUSIONS : The optimized fermentation medium developed in this study can probably be used to improve spinosad production in screening industrial strains of S. - pubmed
Mantle cell lymphoma ( MCL ) is a highly chemo - refractory tumor with generally poor outcome , especially if the patients develop resistance to frontline drugs . - pubmed
METHODS : A retrospective cohort study using the Taiwan National Health Insurance claims database was conducted to examine the risks of HHF among newly diagnosed type 2 diabetic patients who initiated glinide , sulfonylurea , or acarbose therapy during 2006 - 2012 . - pubmed
CONCLUSIONS : These findings indicated that , as compared with acarbose , glinide may be associated with a higher risk of HHF for type 2 diabetic patients . - pubmed
To understand the molecular mechanisms behind the LE apricot phenotype , comparative transcriptomes of Prunus armeniaca L. were sequenced using Illumina HiSeq 2500 . - pubmed
Most vertebrates show concussion responses when their heads are hit suddenly by heavy objects . - pubmed
Although , preoperative modalities like computed tomography , magnetic resonance image and serology generally help in establishing the diagnosis , but hydatid cysts with unusual localizations and atypical imaging findings may complicate the diagnosis and need be considered in the differential diagnosis of all cystic masses in all anatomic locations , especially in endemic areas , so as to reduce the patient morbidity and mortality . - pubmed
Imaging children , especially with developmental disorders , requires extra considerations related to hyperactivity , anxiety and the ability to perform and maintain attention to the fMRI paradigm . - pubmed
Methods : Initial clinical presentations including psychiatric symptoms , treatment details , and outcome with respect to psychiatric symptoms were collected from medical case records of children aged less than 18 years with seropositive NMDAR encephalitis from a single tertiary care center ( May 2010 - November 2016 ) . - pubmed
All 21 children presented with psychiatric symptoms at initial presentation . - pubmed
In addition to psychiatric symptoms , at least 1 of the following was also seen in all children : speech disturbance ( 85.7 % , n = 18 ) , seizure ( 85.7 % , n = 18 ) , or movement disorder ( 76.2 % , n = 16 ) . - pubmed
A comorbid psychiatric diagnosis ( ICD-10 criteria ) was made in 11 children ( 52.4 % ) ; the most common was organic mood disorder ( n = 6 ) . - pubmed
Three of the 4 children with residual psychiatric symptoms and persistent academic difficulties were prepubertal . - pubmed
Disease progression occurred in 44/108 ( 40.7 % ) patients and 13/108 ( 12 % ) patients died . - pubmed
The median progression - free survival was 11.2 years , and as more than 80 % of patients were alive 10 years after metastatic breast cancer diagnosis . - pubmed
Disease progression occurred in 4 of the 27 patients after the interruption of trastuzumab treatment . - pubmed
This case highlights the importance of recognizing mechanisms other than heart block as a cause of sudden death in a patient with KSS . - pubmed
Patients with vitreomacular traction ( VMT ) syndrome without a full - thickness macular hole were included if they received an intravitreal injection ( IVI ) of ocriplasmin . - pubmed
We were able to combine them into a formula , ultimately allowing the calculation of an individual probability of treatment success with ocriplasmin in patients with VMT syndrome without FTHM . - pubmed
The approach could yield anatomical hypotheses about brain connectivity , motivate rational strategies for treating mood disorders with deep brain stimulation , and could be extended to animal studies that use combined optogenetic fMRI . - pubmed
BACKGROUND : Post - operative nausea and vomiting ( PONV ) is one of the most important causes of patient discomfort after laparoscopic surgeries despite the use of a multimodal pharmacological approach . - pubmed
This study assessed whether the addition of aprepitant to a multimodal regimen would further decrease the incidence of PONV in high - risk patients . - pubmed
METHODS : Apfel - score three or four patients , scheduled for laparoscopic procedures to treat abdominal or pelvic cancer , were randomized to receive oral starch ( control group ) or 80 mg of oral aprepitant ( treatment group ) before induction of anaesthesia in a double - blind study . - pubmed
Vomiting occurred in 13/32 ( 40.6 % ) patients in the control group and in 1/34 ( 2.9 % ) patients in the treatment group ( P = 0.0002 , 95%CI : 18 - 54 % ) in the first 24 h after anaesthesia . - pubmed
Adolescent Synthetic Cannabinoid Exposure Produces Enduring Changes in Dopamine Neuron Activity in a Rodent Model of Schizophrenia Susceptibility . - pubmed
Background : Epidemiological studies recognize cannabis intake as a risk factor for schizophrenia , yet the majority of adolescents who use marijuana do not develop psychosis . - pubmed
Methods : We recently developed a novel rodent model of schizophrenia susceptibility , the F2 methylazoxymethanol acetate rat , where only a proportion ( ~40 % ) of rats display a schizophrenia - like phenotype . - pubmed
Results : Adolescent synthetic cannabinoid exposure significantly increased the proportion of susceptible rats displaying a schizophrenia - like hyperdopaminergic phenotype after puberty without producing any observable alterations in control rats . - pubmed
Conclusions : Taken together , these studies provide experimental evidence that adolescent synthetic cannabinoid exposure may contribute to psychosis in susceptible individuals . - pubmed
LC - HRMS determination of piperine on rat dried blood spots : A pharmacokinetic study . - pubmed
Lenalidomide at the dose of 25 mg every other day in patients affected by multiple myeloma and renal failure : a real - life experience . - pubmed
Renal impairment ( RI ) is a relevant complication of patients affected by multiple myeloma ( MM ) ; it can be present in up to 30 - 35 % of newly diagnosed MM and is linked to a poor outcome . - pubmed
Dose reduction is mandatory in RI ; however , there is no theoretical assumption against the possibility that protracting the time of full standard doses can be equally effective and tolerated by patients requiring reduced doses . - pubmed
In this report , we describe our retrospective experience , in 18 patients , with the administration of lenalidomide 25 mg every other day for patients with MM and RI . - pubmed
It is known that the prevalence of thyroid disease is higher among diabetic patients than in general population . - pubmed
Therefore , we conclude that the treatment with MSC was able to reverse the increased thyroid H2O2 generation in diabetic animals and in PCCL3 cells exposed to high glucose , an effect probably mediated by EV produced by these cells , acting in a paracrine fashion . - pubmed
The in vitro cytotoxicity effect of AgNPs showed promising anticancer activity against human breast cancer MCF-7 cells . - pubmed
MATERIAL AND METHODS : We analysed thirty patients with HCC for multiple clinic - pathological characteristics . - pubmed
Metastatic Castration - Sensitive Prostate Cancer : Optimizing Patient Selection and Treatment . - pubmed
Although androgen - deprivation therapy ( ADT ) is still the backbone of treatment , the addition of docetaxel or abiraterone acetate has improved outcomes for patients with mCSPC and become standard of care . - pubmed
With multiple treatment options available for patients with mCSPC , treatment selection to optimize patient outcomes has become increasingly difficult . - pubmed
Although surgery and/or radiation are standard of care for localized , intermediate- and high - risk prostate cancer , these treatments are not routinely used as part of initial treatment plans for patients with de novo mCSPC . - pubmed
Aneuploidy is associated with different human diseases including cancer . - pubmed
Acute toxoplasmosis and antioxidant levels in the liver , kidney and brain of rats Toxoplasma gondii is a common protozoan parasite which causes toxoplasmosis worldwide . - pubmed
In 2011 and 2012 , 22 consecutive patients with cervical medullary syndrome and geneticist - confirmed hereditary connective tissue disorder ( HCTD ) , with Chiari malformation ( type 1 or 0 ) and kyphotic clivo - axial angle ( CXA ) enrolled in the IRB - approved study ( IRB # 10 - 036 - 06 : GBMC ) . - pubmed
Symptoms , patient satisfaction , and work status were assessed by a third - party questionnaire , pain by visual analog scale ( 0 - 10/10 ) , neurologic exams by neurosurgeon , function by Karnofsky performance scale ( KPS ) . - pubmed
Two patients returned to surgery for a superficial wound infections , and two required transfusion . - pubmed
All patients who had rib harvests had pain related that procedure ( 3/10 ) , which abated by 5 years . - pubmed
The results support the literature , that open reduction of the kyphotic CXA to lessen ventral brainstem deformity , and fusion / stabilization to restore stability in patients with HCTD is feasible , associated with a low surgical morbidity , and results in enduring improvement in pain and function . - pubmed
This study determined whether and how prenatal hypoxia may cause malignant hypertension and impaired vascular functions in spontaneous hypertension rat ( SHR ) offspring at adolescent stage . - pubmed
METHODS : A multicenter retrospective analysis was performed from March 2014 to April 2017 to assess 30- and 90 - day clinical cure and adverse drug events ( ADEs ) in adult patients who received & gt;= 1 dose of dalbavancin for a non - ABSSSI indication . - pubmed
At day 90 , relapse occurred in two patients . - pubmed
Three patients had a potential dalbavancin - associated ADE : two patients with renal dysfunction and one patient with pruritus . - pubmed
CONCLUSIONS : This study demonstrates a possible role for dalbavancin in the treatment of non - ABSSSI invasive gram - positive infections in select vulnerable OPAT patients . - pubmed
RESULTS : A total of 50 women with uterine sarcoma were identified and lesions included 43 leiomyosarcomas ( 86 % ) and seven high grade sarcomas ( 14 % ) . - pubmed
Thirty - nine patients ( 78 % ) had a recurrence : 22 had only metastatic recurrence ( 58 % ) , two had isolated pelvic recurrence ( 5 % ) and 15 had pelvic and metastatic recurrence ( 38 % ) . - pubmed
Results : Eight thousand eleven diabetic patients and 1635 normal controls from 27 studies were included . - pubmed
Characterization of Novel Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys . - pubmed
A variety of animal models of diabetes mellitus ( DM ) are required to study the genetics and pathophysiology of DM . - pubmed
The most commonly used plant families for pneumonia and tuberculosis therapy in the study region were Asteraceae , Bignoniaceae and Fabaceae ( seven plants in each ) ; of these , Curcuma longa L. , Punica granatum L. and Justicia adhatoda L. carried the most inhibiting potential against Staphylococcus aureus and Streptococcus pneumoniae while that of Acalypha indica L. against Mycobacterium tuberculosis . - pubmed
BACKGROUND : The use , misuse and co - use of alcohol , cannabis , tobacco , and other licit and illicit controlled substances has increased in past decades leading to higher rates of morbidity , overdose , and mortality in women of reproductive age . - pubmed
This report is the first instance in which a patient with severe PAH , survived a successful atrial septal defect ( ASD ) repair and bilateral lung transplantation during puerperium . - pubmed
PATIENT CONCERNS : A 42 - year - old pregnant woman with congenital heart disease ( CHD ) and severe PAH was admitted to our hospital for the management of pregnancy and delivery . - pubmed
The patient was diagnosed with severe PAH in 2013 , and no significant improvements or deteriorations were found until this pregnancy - related hospital admission . - pubmed
DIAGNOSIS : The patient was diagnosed with CHD and severe PAH in 2013 with color Doppler echocardiography , right cardiac catheterization , and pulmonary perfusion imaging . - pubmed
The patient 's mean pulmonary arterial pressure increased to 140 mm Hg during pregnancy , suggesting an exacerbated PAH with high risks to both her and the unborn child . - pubmed
Ginsenoside Rb1 , A Major Saponin from Panax ginseng , Exerts Protective Effects Against Acetaminophen - Induced Hepatotoxicity in Mice . - pubmed
Previous reports indicated liver failure could be alleviated by saponins ( ginsenosides ) from Panax ginseng against APAP - induced inflammatory responses in vivo . - pubmed
CONCLUSIONS : Findings suggest that Korean white - collar workers , particularly professionals , have elevated levels of inflammation . - pubmed
The atopic dermatitis itch scale : development of a new measure to assess pruritus in patients with atopic dermatitis . - pubmed
Materials and methods : Six focus groups were conducted with 49 patients with AD ( 32 adults ; 17 adolescents ) . - pubmed
Three iterative rounds of cognitive debriefing interviews were conducted in 26 patients with AD ( 17 adults ; 9 adolescents ) to pretest and refine the instrument . - pubmed
Methods Professionally active men aged 20 - 65 with distal radius fracture were followed prospectively for 1 - year ( n = 88 ) . - pubmed
Decreased FO prevents improvement of gait and muscle recovery and residual LLD has a prominent influence on patient satisfaction with THA , while few studies have investigated the relationship between FO and/or LLD and gait disturbances . - pubmed
METHODS : We evaluated 92 patients ( including 20 patients who underwent gait analysis ) in whom total hip arthroplasty was performed for unilateral evere osteoarthritis of the hip joint . - pubmed
The Glucose Lowering Effect of Zornia gibbosa Span Extracts in Diabetic Rats . - pubmed
Materials and Methods : This acute toxicity study was conducted for ethyl acetate and ethanol ( 70%v / v ) extracts of Z. - pubmed
The anti - diabetic activity of selected plant extracts were tested using alloxan - induced diabetes in a rat model . - pubmed
Zornia gibbosa significantly decreased glucose concentrations and restored the altered enzymes levels caused by damage to different organs by diabetes . - pubmed
All patients had mesh introduced through a 10 - 12 - mm port placed through the ventral hernia defect . - pubmed
Lameness , injuries , and cleanliness are considered important indicators of dairy cow welfare , milk production , and milk quality . - pubmed
A wide variation was detected in the true prevalence of the different cow - based measurements among herds ( lameness : range = 19 - 72 % , median = 36 % ; neck injuries : range = 0 - 65 % , median = 14 % ; knee injuries : range = 0 - 44 % , median = 12 % ; hock injuries : range = 0 - 57 % , median = 25 % ; dirty udder : range = 0 - 55 % , median 13 % ; dirty legs : range = 0 - 91 % , median = 18 % ; and dirty flanks : range = 0 - 82 % , median = 20 % ) . - pubmed
Intraoperatively , the patient suffered a dural injury that was repaired . - pubmed
Postoperatively , the patient was electively ventilated for three days , continued with remote cerebellar hemorrhage ( RCH ) treatment and precaution , and extubated on the third day as the patient 's neurological function continued to improve . - pubmed
Aloe vera : A medicinal plant used in skin wound healing . - pubmed
Skin injury is a major problem threatening human physical and mental health , how to promote wound healing has been the focus . - pubmed
Many studies have shown that Aloe vera plays an important role in promoting wound healing . - pubmed
Adding Aloe vera to wound dressing has become an ideal way . - pubmed
This review will describe the process of skin injury and wound healing , and analyze the role of Aloe vera in wound healing . - pubmed
In addition , the types of wound dressing and the applications of Aloe vera in wound dressing will be discussed . - pubmed
The hallmark of this unregulated inflammatory response includes viral sepsis , pneumonitis shock , coagulopathy , and acute respiratory distress syndrome ( ARDS ) which is the major cause of death in COVID-19 patients . - pubmed
Hypervascular hepatic mass in a patient with breast cancer . - pubmed
The protective effects of trelagliptin on high - fat diet - induced nonalcoholic fatty liver disease in mice . - pubmed
Nonalcoholic fatty liver disease ( NAFLD ) occurs in patients with type 2 diabetes mellitus ( T2DM ) . - pubmed
In this study , we aimed to investigate the roles of trelagliptin in the development of NAFLD in a mouse model . - pubmed
To induce NAFLD disease , C57BL/6 mice were fed a high - fat diet for 10 weeks . - pubmed
A 56 - year - old man presented at a local hospital with nausea , vomiting , epigastric pain , and white stool . - pubmed
aureus ( MRSA ) strains in in vitro models of endophthalmitis . - pubmed
An analysis of the occurrence of gallbladder disease ( ie , cholelithiasis , cholecystitis , cholecystectomy ) in 210 consecutive patients with primary hyperlipoproteinemia showed that the prevalence of gallbladder disease was 8 % , 18 % , and 42 % in males with type IIa , IIb , and IV hyperlipoproteinemia , and 22 % , 48 % , and 72 % in the corresponding groups of females . - pubmed
Translocation and sperm abnormality assays in mouse spermatogonia treated with procarbazine . - pubmed
The levels of plasma free carnitine and ketone bodies have been found to fluctuate inversely in fasting individuals without muscle disease . - pubmed
A patient with lipid storage myopathy and muscle carnitine deficiency , and his two daughters , developed exaggerated ketogenesis on fasting . - pubmed
Three urinary excretion tests of vitamin B12 absorption were done in 12 patients with classic pernicious anemia . - pubmed
Presurgical identification of hibernating myocardium by combined use of technetium-99 m hexakis 2 - methoxyisobutylisonitrile single photon emission tomography and fluorine-18 fluoro-2 - deoxy - D - glucose positron emission tomography in patients with coronary artery disease . - pubmed
Segmental wall motion , perfusion and 18F - FDG uptake were scored in 5 segments in 14 patients with coronary artery disease ( CAD ) , for a total number of 70 segments . - pubmed
The survival of hepatocellular carcinoma patients is very low , mainly due to the lack of effective treatments . - pubmed
In addition , progesterone has been used to treat a few hepatocellular carcinoma patients with promising responses . - pubmed
Fibrodysplasia ossificans progressiva : a clue from the fly ? - pubmed
Economic evaluation of prophylactic treatment with Misoprostol in osteoarthritic patients treated with NSAIDs . - pubmed
It is demonstrated in clinical studies that Misoprostol is effective in preventing gastric ulcers in osteoarthritic patients treated with non - steroidal anti - inflammatory drugs ( NSAIDs ) . - pubmed
From January 1987 until October 1989 , 96 patients have been treated with radical cystectomy for locally advanced bladder cancer . - pubmed
Cardiopulmonary receptor reflexes in normotensive athletes with cardiac hypertrophy . - pubmed
The ultrastructural evidence of papillomavirusparticles within the nucleus of koilocytes are hints at a possible human papillomavirus etiology of vulvar carcinoma . - pubmed
The structural brain mutant Vacuolar medulla of Drosophila melanogaster with specific behavioral defects and cell degeneration in the adult . - pubmed
Cerebral and systemic metabolism of oxygen , glucose , lactate , pyruvate , beta - hydroxybutyrate , acetoacetate , and amino acids were studied in 27 comatose patients during the first 7 days after a head injury . - pubmed
Unlike the fasting state in normal man , in which beta - hydroxybutyrate and acetoacetate are important metabolic substrates , cerebral metabolism after head injury is almost totally dependent upon the aerobic and anaerobic metabolism of glucose . - pubmed
The formation of separate clusters of Mb values enabled us to distinguish patients with different types of MD according to the clinical diagnosis . - pubmed
[ Canine model of respiratory distress syndrome induced by bone marrow extraction and pathological observation of the lung tissue ] . - pubmed
A case of intracranial malignant teratoma found in a 27 - year - old man was reported . - pubmed
In addition , satisfactory retrieval of the three separate organs or of the heart and a separate bilateral lung block was done in six human cadavers . - pubmed
A 59 - year - old white woman was admitted with reduced vision and a painless swelling in the area of the right lacrimal gland . - pubmed
A case is presented of severe pancreatic injury in a 30 - year - old man following a road traffic accident . - pubmed
The efficacy of supplemental fresh frozen plasma ( FFP ) therapy after massive packed red cell ( PRBC ) replacement for hemorrhagic shock was studied in 22 conditioned dogs . - pubmed
Consequently , routine FFP therapy for its procoagulant effects after hemorrhagic shock should be abandoned pending controlled studies in man . - pubmed
Microtubule arrays in taxol - treated mouse dorsal root ganglion - spinal cord cultures . - pubmed
The diagnostic yield of EMG is emphasized in the evaluation of 122 children with hypotonia and weakness ( all under 3 years old ) ; abnormalities were demonstrated in 48 % leading to the diagnosis of spinal muscular atrophy in 16 % , of congenital myopathies in 11 % , and of peripheral neuropathies in 8 % . - pubmed
In 103 children with hypotonia associated with mental deficiency and/or seizures , evidence of a peripheral neuropathy was shown in 20 % . - pubmed
4 cases of anatomically confirmed primary hyperparathyroidism ( age of patients 58 - 78 years ) were admitted with a serum calcium of over 4 mmol / l in one case , over 3,5 mmol / l in a second case and over 3 mmol / l in the other two . - pubmed
Relative immunogenicity of the cold - adapted influenza virus A / Ann Arbor / 6 / 60 ( A / AA / 6 / 60 - ca ) , recombinants of A / AA / 6 / 60 - ca , and parental strains with similar surface antigens . - pubmed
All ca viruses were less immunogenic than their wild - type parental strains by a factor of 10(1.3 ) to 10(3.4 ) , probably due to the restricted capacity of ca viruses to replicate in the respiratory tracts of mice . - pubmed
When two doses consisting of 10(5.0 ) 50 % tissue culture infective doses of A / Ann Arbor/6/60 - ca were administered at an interval of 3 weeks , solid immunity was induced against the wild - type A / Ann Arbor / 6 / 60 parental virus , two heterologous H3N2 strains , and an H1N1 strain . - pubmed
Public opinion has been responsible for several state legislatures enacting bills allowing the use of laetrile for patients with leukemia and other malignancies . - pubmed
We recently cared for a 3 1/2 - year - old child with acute lymphoblastic leukemia , who had low initial white blood cell count , limited organomegaly , and absence of T or B cell markers . - pubmed
Despite favorable prognosis , the child developed several relapses and died with widespread infiltration of leukemia in the central nervous system , bone marrow and viscera . - pubmed
The effect of schistosome infection on the presence and maturation of splenic T lymphocytes in C3H / HeN nu / nu and nu/+ mice was examined . - pubmed
In contrast , the mean titer of sera from six nu/+ mice was log2 10.7 Nu/+ mice had typical florid lesions , but nu / nu mice mounted sparse granulomatous reactions around eggs in the liver without evidence for hepatocellular damage . - pubmed
Dispersed liver granulomas of nu / nu mice contained 1.2 % T and 20.3 % B lymphocytes . - pubmed
[ An experimental study of pyrithiamine - induced encephalopathy in the rat . - pubmed
100 MS patients were followed up for an average of 5 years . - pubmed
A patient is described who presented with a scleral defect which appeared dangerously close to perforation . - pubmed
We examined the effectiveness of 5 anticancer agents in nude mice transplanted with 4 kinds of uterine cervical adenocarcinoma . - pubmed
The therapeutic effects were assessed in terms of growth inhibition rates and histological effects in the transplanted tumors of nude mice . - pubmed
Toxicity of sulphur mustard in adult rat lung organ culture . - pubmed
The toxicity of the chemical warfare agent sulphur mustard , ( bis -( 2 - chloroethyl ) sulphide , HD ) , was examined in adult rat lung organ cultures . - pubmed
A 28 - year - old , previously healthy , normotensive woman suddenly developed an acute pseudobulbar palsy with dysarthria , dysphagia , hypernasal voice and mild right arm paresis . - pubmed
Prognostic factors and treatment results were analysed in 28 consecutive patients with primary gastric lymphoma ( PGL ) diagnosed and treated , all by surgery and in many cases with additional chemotherapy ( CT ) and/or radiotherapy ( RT ) , between 1977 and 1988 . - pubmed
According to the Kiel - classification 18 patients had a low - grade and 9 patients a high - grade lymphoma . - pubmed
Eighteen patients with age - related macular degeneration developed subfoveal membranes that were surgically removed and submitted for histopathological examination . - pubmed
A patient with idiopathic hypertrophic spinal pachymeningitis ( HSP ) with predominant involvement of the cervical and thoracic dura is reported . - pubmed
According to a review of the English and Japanese literature on idiopathic HSP , the prognosis of patients with positive inflammatory signs is worse than that of those with no inflammatory signs . - pubmed
Magnetic resonance ( MR ) imaging and localized proton MR spectroscopy of the occipital lobes were performed in a patient with cortical blindness following brain trauma . - pubmed
Six weeks after the trauma , MR images showed cortical lesions in both occipital lobes , while the spectra showed elevated lactate and decreased N - acetyl aspartate levels relative to those of healthy volunteers . - pubmed
[ Psychosocial outcome after individualized neuropsychological rehabilitation of patients with brain injuries ] . - pubmed
[ A depression of respiratory function following the cardiopulmonary bypass in infants and children ] . - pubmed
Pouchitis disease course after orthotopic liver transplantation in patients with primary sclerosing cholangitis and an ileal pouch - anal anastomosis . - pubmed
METHODS : Seven patients with an ileal pouch - anal anastomosis for ulcerative colitis underwent liver transplantation for primary sclerosing cholangitis . - pubmed
RESULTS : Five of seven patients had pouchitis before transplant [ recurrent acute ( n = 3 ) , chronic ( n = 2 ) ] , and four of those five continued to have pouchitis after transplant ( all chronic ) . - pubmed
CONCLUSION : Pouchitis occurs frequently in patients with primary sclerosing cholangitis and an ileal pouch - anal anastomosis for ulcerative colitis . - pubmed
Liver transplantation does not alter the disease course of pouchitis for most of these patients . - pubmed
A total of 218 serum samples were studied : 102 samples from 72 GCT patients and 116 from patients with liver diseases . - pubmed
CAI is in phase I clinical trial for patients with advanced cancers , yielding plasma concentrations in the in vitro anti - angiogenic range . - pubmed
Modulatory effect of tamoxifen and ICI 182,780 on adriamycin resistance in MCF-7 human breast - cancer cells . - pubmed
In this study the ability of the new pure anti - estrogen ICI 182,780 to modulate the cytotoxic action of adriamycin ( ADR ) on parental and ADR - resistant MCF-7 ( MCF-7 ADRr ) human breast - cancer cells was investigated and compared with that of tamoxifen ( TAM ) . - pubmed
In this paper , we review some of the pertinent follow - up studies of patients with panic disorder treated with antidepressants , high - potency benzodiazepines , and cognitive behavior therapy , as well as data from longitudinal studies . - pubmed
In summary , in a group of 55 patients with Barrett ' s esophagus and dysplasia , the authors have reported the ablation of seven superficial cancers , the elimination of dysplasia in 42 of the 55 patients , the complete elimination of Barrett 's mucosa in 16 patients , and the reduction of the extent of Barrett 's mucosa in all patients who were treated with PDT and were maintained on long - term omeprazole . - pubmed
Repeated PDT sessions were required in some patients to accomplish elimination of dysplasia . - pubmed
Esophageal strictures occurred in 53 % of patients , but were treated satisfactorily with dilation . - pubmed
The authors are carefully following the patients treated with longer PDT balloons to evaluate the long - term effects on dysplasia . - pubmed
The authors ' results indicate that PDT alone or in combination with thermal ablation can eliminate superficial cancers , dysplasia , and Barrett ' s mucosa in many patients with Barrett ' s esophagus . - pubmed
Tumor - bearing mouse plasma evidenced high fluorescence values in the absence of oligonucleotide administration , presumably because of elevated intrinsic plasma DNA fragments . - pubmed
The aim of this phase II study was to examine the efficacy of combination chemotherapy comprising epirubicin , cisplatin and protracted infusion 5 - fluorouracil in patients with metastatic prostate cancer . - pubmed
In patients of 70 years and under with prostate cancer resistant to androgen - deprivation therapy and who still have good performance status , ECF chemotherapy can achieve useful remissions . - pubmed
All three showed excellent oral bioavailability in vivo in nude mice and cynomolgus monkeys and exhibited excellent antitumor efficacy against a series of tumor cell lines when dosed orally in nude mice . - pubmed
Induction of squamous cell carcinomas in the salivary glands of rats by potassium iodide . - pubmed
In a 2 - year carcinogenicity study of potassium iodide ( KI ) in F344 / DuCrj rats , squamous cell carcinomas ( SCCs ) were observed in the salivary glands of 4/40 males and 3/40 females receiving 1000 ppm KI in the drinking water . - pubmed
Ductular proliferation with lobular atrophy was observed at high incidence in the submandibular glands of the high - dose animals , and squamous metaplasia was frequently evident within the proliferative ductules and the larger interlobular ducts . - pubmed
OBJECTIVE : The incidence and course of neuropsychiatric symptoms were determined in pediatric patients with rheumatic fever . - pubmed
RESULTS : Obsessive - compulsive symptoms abruptly appeared and peaked during the 2 months after the onset of rheumatic fever in 21 patients with chorea ( 70.0 % ) and were absent in all patients without chorea . - pubmed
Obsessive - compulsive disorder ( OCD ) was diagnosed in five patients with chorea ( 16.7 % ) . - pubmed
The nasal cavity is the major target for tumor induction in the rat following inhalation . - pubmed
The present study shows that morphine reduces the pulmonary inflammatory response to intranasal influenza virus infection in rats . - pubmed
Male Lewis rats were implanted with 75 mg morphine pellets or placebo pellets 72 hours prior to intranasal RAIV infection . - pubmed
Rats were euthanized at 2 , 24 , 48 , 72 , and 96 hours after infection . - pubmed
Placebo - treated rats showed a marked inflammatory response to RAIV infection , and morphine - treated rats mounted less vigorous inflammatory responses to the infection . - pubmed
Effect of dofetilide on survival in patients with supraventricular arrhythmias . - pubmed
OBJECTIVES : This study compared survival between patients taking dofetilide and patients taking placebo in a pooled analysis of randomized clinical trials of patients with supraventricular arrhythmias . - pubmed
BACKGROUND : Clinical trials of antiarrhythmic drugs used to treat supraventricular arrhythmias rarely include enough patients to assess whether the drug being tested has an effect on survival . - pubmed
METHODS : Data from randomized clinical trials of antiarrhythmic drug therapy of supraventricular arrhythmias were pooled to assess the effect on survival of dofetilide ( n = 1346 ) compared with placebo ( n = 677 ) in this patient population . - pubmed
CONCLUSIONS : The pooled survival analysis provided reassurance regarding the safety of dofetilide in patients with supraventricular arrhythmias . - pubmed
In 125 patients who were suspected of having breast cancer by clinical examination , ultrasound , and X - ray mammography , additional bilateral MRM was performed . - pubmed
The protection period from bites by Ae . - pubmed
The paper presents the first experience with the Russian blood substitute Perfluorane at pulmonectomy and pleuropulmonectomy in patients with pulmonary tuberculosis . - pubmed
PF used in a patient with severe chronic respiratory failures provided a beneficial clinical effect , improved the rheological properties and bioenergy of red blood cells ; however , the latter showed an increase in lipid peroxidation . - pubmed
In patients with coronary artery disease and intractable angina , who are not candidates for either coronary artery bypass grafting ( CABG ) or percutaneous transluminal coronary angioplasty ( PTCA ) , transmyocardial laser revascularization ( TMR ) has been developed as a new treatment . - pubmed
In this study 32 newly diagnosed anaplastic oligoastrocytoma patients were enrolled ( median age of 41 years , range 19 - 63 ; median Karnofsky performance status of 90 , range 70 - 100 ) . - pubmed
This schedule of treatment provides durable response in a selected group of anaplastic oligoastrocytoma patients . - pubmed
Risk for human tick - borne encephalitis , borrelioses , and double infection in the pre - Ural region of Russia . - pubmed
Lymph node metastasis is the most frequent type of tumor recurrence and is known to be one reason for the poor prognosis in patients with digestive cancer . - pubmed
Histologically , lymphatic invasion of cancer cells was found in primary gastric tumors of control mice with lymph node metastasis . - pubmed
However , no lymphatic invasion was observed in the gastric wall of R-94138 - treated mice without lymph node metastasis . - pubmed
[ Effects of alfacalcidol on osteoporosis in ovariectomized rats ] . - pubmed
OBJECTIVE : To investigate the effects of alfacalcidol on osteoporosis in rats induced by ovariectomy ( OVX ) . - pubmed
CONCLUSION : Alfacalcidol effectively prevent bone loss in OVX rats and restore partly the trabecula , with evidenced increasing density , contents as well as maximal loads of cancellous bone , and reduce bone resorption . - pubmed
[ Mechanisms of the development of venous hypertension in patients with varicose disease ] . - pubmed
The examination of 539 patients with varicose disease was fulfilled with the help of ultrasonic ( dopplerography , angioscanning ) , rentgenological ( phlebography , lymphography ) , functional ( rheovasography , photoplethysmography ) methods . - pubmed
CONCLUSION : Milk thistle in commonly administered dosages should not interfere with indinavir therapy in patients infected with the human immunodeficiency virus . - pubmed
Current guidelines for optimal blood pressure levels in obese patients or for the treatment of obesity - hypertension do not provide specific recommendations that go beyond the rather general recommendation to lose weight . - pubmed
Based on the strong ties between obesity , hypertension , and type 2 diabetes , and the similarity of complications that occur in obesity - related hypertension and in hypertension associated with type 2 diabetes , it seems appropriate to explore the optimal blood pressure levels for obese hypertensive patients . - pubmed
The role of antiobesity drugs in the management of the obese hypertensive patient also remains to be defined . - pubmed
Here , we show that chromosomal abnormalities , including aneuploidy and chromosome rearrangement , were significantly increased in yeast diploid cells with defects in the origin recognition complex . - pubmed
The bactericidal activity of phlorotannins from brown algae against food - borne pathogenic bacteria ( 25 strains ) , methicillin - resistant Staphylococcus aureus ( MRSA ) ( nine strains ) and Streptococcus pyogenes ( one strain ) was examined and compared with that of catechins . - pubmed
This article discusses phase I and II trials of neuronal transplantation in humans with small strokes in critical brain locations such as the basal ganglia region . - pubmed
STUDY DESIGN : This is a case report of a patient with renal cell carcinoma and intradural metastasis to the cauda equina . - pubmed
METHODS : A 61 - year - old man who underwent a nephrectomy for the treatment of renal cell carcinoma presented with worsening low back pain that radiated to both legs . - pubmed
The patient 's low back pain and radiating leg pain were relieved after operating . - pubmed
Magnetic resonance imaging is a useful tool for detecting intraspinal metastasis when the patient is complaining of a unique pain . - pubmed
Cost - effectiveness analysis of tacrolimus ointment versus high - potency topical corticosteroids in adults with moderate to severe atopic dermatitis . - pubmed
OBJECTIVE : We sought to compare cost - effectiveness of high - potency topical corticosteroids ( HPTCs ) and tacrolimus ointment for the treatment of moderate to severe atopic dermatitis for patients who are not responsive to or not well controlled with mid - potency topical corticosteroids . - pubmed
[ Rhythmic fast activity on EEG in a patient with Mollaret ' s meningitis ] . - pubmed
The patient , a 16 - year - old boy , had episodes of acute encephalitis followed by complete recovery every year from the age of 13 to 16 years . - pubmed
Cell migration and programmed cell death of Drosophila germ cells . - pubmed
Cell migration and programmed cell death are essential components of animal development and homeostasis , and the germ cells of Drosophila provide a simple genetic system to study the molecular mechanisms that govern these important cellular processes . - pubmed
In addition , cell migration and cell death mechanisms are often linked , as it is important to eliminate cells that are misplaced and could present a danger to the organism . - pubmed
In Drosophila , genes involved in germ cell migration can also affect programmed cell death . - pubmed
Here , I provide a brief review of Drosophila germ cell migration and programmed cell death at both the descriptive and molecular levels . - pubmed
Response of the Syrian hamster to two strains of rabies street virus by rectal instillation . - pubmed
[ Acute human poisoning by trichloroethylene followed by hepatopathy and hyperglycemic glycosuria ] . - pubmed
Genes on the Y chromosome influencing rate of maturation in man : skeletal age studies in children with Klinefelter ' s ( XXY ) and Turner ' s ( XO ) syndromes . - pubmed
[ CLINICAL ANALYSIS OF 98 PATIENTS WITH OBSTRUCTIVE JAUNDICE ] . - pubmed
Malignant hemopathies , although heterogeneous in their prognosis and oncogenesis , represent an interesting model for studying cancer genesis mechanisms in man through the recurrent presence of genetic abnormalities involved in oncogenesis and the availability of tumour material . - pubmed
Normal hepatic glycogen storage after fasting and feeding in children and adolescents with type 1 diabetes . - pubmed
OBJECTIVE : Hypoglycemia is the most important acute complication in patients with type 1 diabetes . - pubmed
To test the hypothesis whether abnormal storage of glycogen in the liver is contributing to the risk of hypoglycemia in type 1 diabetic children and adolescents , liver glycogen was measured . - pubmed
STUDY DESIGN : Hepatic glycogen concentrations were measured in 19 type 1 diabetic children and adolescents as well as in 19 age - matched controls , following overnight fasting and 4 h after two standardized meals . - pubmed
RESULTS : Mean ( + /- SEM ) fasting hepatic glycogen concentrations measured in arbitrary units ( au ) were similar in type 1 diabetic subjects and controls ( 4.98 + /- 0.36 vs. 4.48 + /- 0.33 au ; p = 0.31 ) . - pubmed
Hepatic glycogen accumulation after feeding was 19.1 % in diabetic children and adolescents compared with 35.8 % in controls , but this difference did not reach significance . - pubmed
CONCLUSION : In children and adolescents with moderately controlled type 1 diabetes , hepatic glycogen stores after fasting and feeding are comparable to those of matched controls . - pubmed
Thirty women ( 13.4 % ) were diagnosed with a recurrence . - pubmed
General gonococcal peritonitis in young girls under puberty ; report of two cases , one simulating appendicitis , operated . - pubmed
It is well documented that the range of the daily fluctuations in IOP is greater in patients with glaucoma than in normal individuals , and a report by Asrani et al . - pubmed
There have been reports of nocturnal increases in IOP , particularly in patients with normal tension glaucoma , and some ophthalmologists believe these may account for progression of visual field loss in some patients with glaucoma . - pubmed
Several recent studies of diurnal IOP in patients with glaucoma have failed to document such diurnal IOP spikes , so the published data available have not supported this hypothesis . - pubmed
SUMMARY : One recent report has reconfirmed that a single IOP measurement in the office may not accurately indicate what is happening to the IOP of a patient with glaucoma throughout the day . - pubmed
Our current knowledge of the molecular pathogenesis of the diffuse adult astrocytic tumours is vast if compared to 20 years ago , yet we are far from understanding the details of this process at the molecular level and using such an understanding to logically and specifically treat patients ' tumours . - pubmed
Lipin is one such protein identified in a lipodystrophic mouse strain and found to be critical for normal adipocyte differentiation . - pubmed
Our aim was to compare these two types of rotationplasty and determine whether the knee should be preserved in children with tumours of the proximal femur . - pubmed
Postimplant chest x - rays were obtained at a median of 912 days ( range 147 to 3023 ) , and 4 patients ( 1.7 % ) experienced at least one seed embolus to the lung . - pubmed
All 4 patients had received an I-125 implant , resulting in a pulmonary embolus rate for I-125 of 2.7 % ( 4 of 146 ) and for palladium-103 of 0 % ( 0 of 92 ) . - pubmed
CONCLUSIONS : Seed embolism to the lungs is a rare event when patients undergo implantation using the real - time method . - pubmed
A canine model of normovolaemic acute anaemia . - pubmed
The objective was to develop a non - terminal , acute normovolaemic anaemia model in dogs that has minimal effects on patient well - being . - pubmed
The model was primarily developed to determine echocardiographic values as well as Doppler abdominal splanchnic blood flow parameters in anaemic dogs as part of a study that will compare these results to similar studies in babesiosis - induced anaemia . - pubmed
The model may also be useful in the evaluation of the pathophysiology of anaemia in dogs or as a model for anaemia in humans . - pubmed
A spontaneous , multisystem autoimmune disease developed in aging ( & gt;20 weeks ) transgenic mice ( n = 25 ) , with a 32 % incidence of arthritis , and by 45 weeks , all mice had developed glomerulonephritis and pneumonitis , and most had antihistone antibodies . - pubmed
METHODS : Sixty sedentary women with FM , ages 18 - 60 years , were randomly assigned to either deep water running ( DWR ) or land - based exercises ( LBE ) . - pubmed
Visual analog scale of pain , Fibromyalgia Impact Questionnaire ( FIQ ) , Beck Depression Inventory , Short Form 36 Health Survey ( SF-36 ) , and a patient 's global assessment of response to therapy ( PGART ) were measured at baseline , week 8 , and week 15 . - pubmed
Therefore , DWR could be studied as an exercise option for patients with FM who have problems adapting to LBE or lower limbs limitations . - pubmed
In the presence of EDTA , the activity of coumermycin A(1 ) was significantly enhanced ( 8- to 40 - fold ) against all four organisms in the synthetic medium lacking Mg ( 2 + ) ; novobiocin activity was increased to a lesser extent ( 4- to 16 - fold ) against three strains and remained unchanged against P. - pubmed
Rates of IPD in the Indigenous and non - Indigenous under 2 - year - old population were similar in 2004 ( 91.5 and 93.6 cases per 100,000 population , respectively ) following a targeted introduction of the 7 - valent pneumococcal conjugate vaccine ( 7vPCV ) in mid-2001 for Indigenous infants and children . - pubmed
The work presented here suggests that , further to its genotoxic properties , at levels close to human exposure PhIP stimulates cellular signalling pathways that are linked to the promotion and progression of neoplastic disease . - pubmed
The patients underwent the corrective refractive procedure by means of LASIK to correct the myopia . - pubmed
We describe a 45 - year - old woman presenting with unilateral proptosis and periorbital xanthelasma . - pubmed
Effect of treatment of hyperuricemia with allopurinol on blood pressure , creatinine clearence , and proteinuria in patients with normal renal functions . - pubmed
However , there is no data about the effect of lowering uric acid level on hypertension , renal function , and proteinuria in patients with glomerular filtration rate ( GFR ) & gt;60 ml / min . - pubmed
We therefore conducted a prospective study to investigate the benefits of allopurinol treatment in hyperuricemic patients with normal renal function . - pubmed
MATERIALS AND METHODS : Forty - eight hyperuricemic and 21 normouricemic patients were included in the study . - pubmed
Hyperuricemic patients received 300 mg / day allopurinol for three months . - pubmed
Hence , management of hyperuricemia may prevent the progression of renal disease , even in patients with normal renal function , suggesting that early treatment with allopurinol should be an important part of the management of chronic kidney disease ( CKD ) patients . - pubmed
A 55 - year - old man was referred to our hospital for progressive dyspnea . - pubmed
The patient died of respiratory failure a month later and an autopsy revealed no significant inflammatory changes in either lung . - pubmed
Antimicrobial effects of photodynamic therapy on patients with necrotic pulps and periapical lesion . - pubmed
As a result human somatic cells undergo replicative senescence , which plays an important role in suppressing tumorigenesis , and at the same time contributes to the process of aging . - pubmed
RESULTS : Bone marrow oedema around the growth plate and joint effusion occurred in all patients . - pubmed
Synovitis occurred in 13/15 patients . - pubmed
6 patients had a fall before presenting with SCFE . - pubmed
9 patients had no fall prior to presentation , physis and periost were intact in 7/9 ; periarticular oedema was not seen . - pubmed
A fulcrum - like alignment , impingement of the epiphysis on the metaphysis with a small area of physical contact , was seen in 8 patients , 6/8 had a prior fall . - pubmed
PURPOSE OF REVIEW : To review the state - of - the - art and new developments in the management of patients with brain metastases . - pubmed
Here , we present in vitro and in vivo preclinical evidence in support of chemosensitization of pancreatic cancer cells by 3,3 - diindolylmethane ( DIM ) , a natural compound that can be easily obtained by consuming cruciferous vegetables . - pubmed
The ligand , HQO , and its complexes were tested against one strain Gram + ve bacteria ( Staphylococcus aureus ) , Gram - ve bacteria ( Escherichia coli ) . - pubmed
OBJECTIVES : We analyzed data from patients with ASC - US LBC and positive HPV test results . - pubmed
The rates of infection by Plasmodium species in mosquitoes were 0.37 % ( 22/5,886 ) for Plasmodium vivax(Grassi & amp ; Feletti ) and 0.10 % ( 6/5,886 ) for Plasmodium falciparum ( Welch ) . - pubmed
darlingi was 2.21 infective bites / person / year , 1.25 for An . - pubmed
To determine whether this proteolytic cascade is altered during the progression of AD , we examined human frontal and parietal cortex tissues from aged subjects with a clinical diagnosis of AD , mild cognitive impairment , or no cognitive impairment . - pubmed
HHV-6 has been associated with encephalitis in children recently . - pubmed
This study aimed to establish a real time PCR assay for simultaneous detection of the two subtypes of HHV-6 , and apply this new assay to children with suspected encephalitis , then analyze the relationship between the infection with HHV-6 and encephalitis in children . - pubmed
There were no cross - reaction with herpes simplex virus type 1 , type 2 ( HSV-1 , HSV-2 ) , varicella - zoster virus ( VZV ) , cytomegalovirus ( CMV ) , Epstein - Barr virus ( EBV ) , hepatitis B virus , Staphylococcus aureus , Mycoplasma pneumoniae and human DNA . - pubmed
HHV-6 positive rate by the real time PCR assay was 4.72 % ( 21/445 ) , including 4 cases with HHV-6A infection , 16 cases of HHV-6B infection and 1 case with mixed HHV-6A and HHV-6B infection . - pubmed
It will provide an early and sensitive diagnosis of HHV-6 encephalitis in children . - pubmed
Functional memory B cells and long - lived plasma cells are generated after a single Plasmodium chabaudi infection in mice . - pubmed
Antibodies have long been shown to play a critical role in naturally acquired immunity to malaria , but it has been suggested that Plasmodium - specific antibodies in humans may not be long lived . - pubmed
The cellular mechanisms underlying B cell and antibody responses are difficult to study in human infections ; therefore , we have investigated the kinetics , duration and characteristics of the Plasmodium - specific memory B cell response in an infection of P. - pubmed
Thus , in this model of malaria , both functional Plasmodium - specific memory B cells and long - lived plasma cells can be generated , suggesting that defects in generating these cell populations may not be the reason for generating short - lived antibody responses . - pubmed
Ethanol produced fatty liver and oxidant stress in WT mice but liver injury ( transaminases , histopathology ) was minimal . - pubmed
Ethanol - induced steatosis and oxidant stress were blunted in the KO mice ( no liver injury ) but restored in the KI mice . - pubmed
Transcription of cytokine genes was evaluated in the lung and spleen of chickens vaccinated with various serotype 1 Marek ' s disease ( MD ) vaccines . - pubmed
Angioplasmocellular hyperplasia : a clinicopathologic study of 10 patients . - pubmed
METHODS : The records of 10 patients ( mean age , 45 years ; range , 17 to 71 years ) with characteristic histologic features of angioplasmocellular hyperplasia were reviewed and the histopathologic findings , clinical features , and medical histories analyzed . - pubmed
Subjective and objective criteria of xerophthalmia and xerostomia were investigated in 120 HCV Egyptian patients . - pubmed
Sixty six of 120 patients ( 55 % ) had SC ; all ( 100 % ) were proved to have xerostomia by sialoscintigraphy and xerophthalmia detected by ophthalmologic tests . - pubmed
Using dacroscintigraphy all SC patients ( 100 % ) were positive for lacrimal drainage abnormalities . - pubmed
High prevalence of SC in HCV Egyptian patients was detected . - pubmed
The genetic diversity of 35 Bacillus sphaericus strains was analyzed by a newly developed multilocus sequence typing ( MLST ) scheme , toxin gene pool survey , and mosquito bioassay . - pubmed
The recently discovered porcine boca - like virus ( Pbo - likeV ) is a member of the Parvoviridae family , genus Bocavirus , and it is potentially associated with swine disease . - pubmed
Several studies have associated Pbo - likeV with postweaning multisystemic wasting syndrome in pigs , but the full spectrum of clinical disease and the epidemiology of Pbo - likeV infection remain unclear . - pubmed
Higher infection rates were found in diseased pigs ( 56.1 % , 101/180 ) compared with healthy pigs ( 16.7 % , 13/78 ) ( P & lt ; 0.05 ) . - pubmed
OBJECTIVE : To study the effect and mechanism of Soybean Isoflavones ( SIF ) on the cognitive performance of female mice after sleep deprivation for 72h . - pubmed
METHODS : A total of 459 patients who underwent curative resection of NSCLC were studied ( median follow - up duration , 4.01 years ) . - pubmed
Different pattern of carotid and myocardial changes according to left ventricular geometry in hypertensive patients . - pubmed
A total of 476 hypertensive patients were prospectively recruited . - pubmed
Carotid arterial function and IMT showed worse values in concentric geometry , whereas LV systolic and diastolic function were worse in hypertrophic geometry , suggesting a discrepancy between carotid arterial and LV function in hypertensive patients . - pubmed
UNLABELLED : A superparamagnetic gammaFe ( 2 ) O ( 3 ) nanocarrier was developed , characterized by spectroscopic methods and evaluated for the delivery of a decoy oligonucleotide ( dODN ) in human colon carcinoma SW 480 cells . - pubmed
Clinical implications of variations in anti - infliximab antibody levels in patients with inflammatory bowel disease . - pubmed
Pharmacological management of type 2 diabetes mellitus in patients with CKD . - pubmed
Effective and appropriate control of blood glucose can significantly reduce the risk of diabetic complications and all - cause mortality in patients with diabetes mellitus and recent years have seen a number of new anti - diabetic medications marketed . - pubmed
However , approximately 30 % of patients with diabetes mellitus develop progressive chronic kidney disease ( CKD ) limiting the selection of agents that can safely be used . - pubmed
Whilst older agents such as metformin and the sulphonylureas remain the mainstay of initial treatment , the elimination and adverse effects profile of a number of these drugs can be a concern in patients with CKD . - pubmed
Treatment guidelines for anti - diabetic therapy rarely consider safe and efficacious management of those patients with CKD . - pubmed
The purposes of the studies were to investigate the cause of low exposure , develop , and test an alternative formulation with improved exposure , and establish the dose to be tested in future studies in cancer patients . - pubmed
CONCLUSION : Amuvatinib LSC , 300 mg every 8 h , is being studied in cancer patients based on the improved exposure and similar safety profile to amuvatinib DPC . - pubmed
The importance of imaging procedures in evaluating painful neck masses : two patients with a painful internal jugular vein thrombosis . - pubmed
METHODOLOGY : We reviewed our hospital charts from Jan 2007 to December 2010 and made a comparative study about early and delayed LC for mild to moderate gallstone pancreatitis in 80 patients . - pubmed
In this study , we reviewed 125 patients with AVMs , demonstrating overall sensitivities of 90 % for CTA , 89 % for T2 - weighted MRI , and 74 % for MRA . - pubmed
The aim of this open - label pilot trial was to evaluate the safety and efficacy of long - term LES stimulation using a permanently implanted LES stimulator in patients with gastroesophageal reflux disease ( GERD ) . - pubmed
The number and timing of sessions was tailored to each patient 's GERD profile . - pubmed
Patients were evaluated using GERD - HRQL , daily symptom and medication diaries , SF-12 , esophageal pH , and high - resolution manometry . - pubmed
At their 6 - month follow - up , 91 % ( 21/23 ) of the patients were off PPI and had significantly better median GERD - HRQL on LES stimulation compared to their on - PPI GERD - HRQL at baseline ( 9.0 vs. 2.0 ; p & lt ; 0.001 ) . - pubmed
Immunotherapies are therefore ideal adjuncts to standard tumor therapies since they aim to activate the patient 's immune system against malignant cells even outside the primary treatment areas ( abscopal effects ) . - pubmed
Self - expanding metal stents for preoperative biliary drainage in patients receiving neoadjuvant therapy for pancreatic cancer . - pubmed
METHODS : Fructose and lactose intolerance ( defined by positive symptom index ) and malabsorption ( defined by increased hydrogen / methane ) were determined in 1372 FGID patients in a single centre using breath testing . - pubmed
BACKGROUND : Prognostic implications of echocardiographic assessment of pulmonary hypertension ( PH ) in non - selected patients hospitalized for acute heart failure ( AHF ) are not clearly defined . - pubmed
METHODS : We prospectively included 1210 consecutive patients admitted for AHF . - pubmed
Patients with significant heart valve disease were excluded . - pubmed
One - year mortality was lower for patients with normal PASP ( 1.32 per 10 person - years ) , intermediate for patients with non - measurable , mild and moderate PH ( 2.48 , 2.46 and 2.62 per 10 persons - year , respectively ) and higher for those with severe PH ( 4.89 per 10 person - years ) . - pubmed
METHODS : ICH patients in a defined Swedish population ( 1.14 million inhabitants ) were prospectively registered during 1996 . - pubmed
Patients surviving 1 year after ICH onset were followed - up regarding survival status and cause of death until December 2009 using data from the National Census Office and the National Cause of Death Register . - pubmed
RESULTS : Of 323 patients with ICH , 172 ( 53 % ) survived after 1 year , 127 ( 39 % ) after 5 years and 57 ( 18 % ) after 13 years . - pubmed
Prognostic impact of cigarette smoking on the survival of patients with established nasopharyngeal carcinoma . - pubmed
BACKGROUND : Cigarette smoking is associated with the etiology of nasopharyngeal carcinoma ; however , the influence of smoking on survival in patients with established nasopharyngeal carcinoma remains unknown . - pubmed
METHODS : We retrospectively analyzed 1,849 patients with nasopharyngeal carcinoma who were categorized as never , former , and current smokers . - pubmed
CONCLUSIONS : Pretreatment cigarette smoking is an independent , poor prognostic factor for patients with nasopharyngeal carcinoma , which is associated with increased risk of death , progression , locoregional relapse , and distant metastasis , with the risk increasing with pack - years . - pubmed
IMPACT : It is clear that cigarette smoking not only promotes carcinogenesis in the normal nasopharyngeal epithelium , but also affects the survival of patients with nasopharyngeal carcinoma . - pubmed
Effects of early and late treatment with L - baclofen on the development and maintenance of tinnitus caused by acoustic trauma in rats . - pubmed
for 4.5 weeks starting at 17.5 weeks following noise exposure ) with l - baclofen on the psychophysical attributes of tinnitus in a conditioned lick suppression model following acoustic trauma in rats . - pubmed
METHODS : This study examined the CSF from 103 patients : bilateral MMD , n=58 ( 56.3 % ) ; unilateral MMD , n=19 ( 18.4 % ) ; atherosclerotic cerebrovascular disease ( ACVD ) , n=21 ( 20.4 % ) ; and control group , n=5 ( 4.9 % ) . - pubmed
The patients rated the ultrasound and fluoroscopic experiences on a scale from 1 to 10 for convenience and pain ; in addition , they indicated their preference between the 2 techniques . - pubmed
The effects of oral L - carnitine treatment on blood lipid metabolism and the body fat content in the diabetic patient . - pubmed
A random double blind study was designed to investigate the effects of L - carnitine treatment ( 12 weeks , 3 g / d ) on lipid metabolism and the fat content of the body in the patients with non - insulin - dependent diabetes mellitus . - pubmed
PATIENTS : From January 2006 to June 2012 , 27 tumors in 17 patients with liver metastases from colorectal cancer were treated using RFA after systemic chemotherapy . - pubmed
One patient had a complication(liver abscess).Of the 27 tumors , 9 were larger than 20 mm in diameter , and 4 of these 9 tumors showed local recurrence after RFA . - pubmed
Male C57BL / 6 mice were fed for 12 weeks with a high - fat diet to induce obesity . - pubmed
USM relaxations induced by NO ( acidified sodium nitrite ) , NO donors ( S - nitrosoglutathione and glyceryl trinitrate ) , and BAY 41 - 2272 [ 5 - cyclopropyl-2 -[ 1 -( 2 - fluoro - benzyl )- 1H - pyrazolo [ 3,4 - b ] pyridin-3 - yl ]- pyrimidin-4 - ylamine ] ( sGC stimulator ) were markedly reduced in obese compared with lean mice . - pubmed
In contrast , USM relaxations induced by BAY 60 - 2770 ( sGC activator ) were 43 % greater in obese mice ( P & lt ; 0.05 ) , which was accompanied by increases in cGMP levels . - pubmed
Long - term oral BAY 60 - 2770 administration fully prevented the impairment of USM relaxations in obese mice . - pubmed
In conclusion , impaired USM relaxation in obese mice is associated with ROS generation and down - regulation of sGC - cGMP signaling . - pubmed
Prevention of sGC degradation by BAY 60 - 2770 ameliorates the impairment of urethral relaxations in obese mice . - pubmed
Hepatic colorectal metastases involving infra - hepatic inferior vena cava in high risk patients for extended resection : an alternative method for achieving radical resection in patient with borderline liver remnant . - pubmed
We believe that aggressive treatment of liver colorectal metastases should be given to all suitable patients . - pubmed
Routine ante - mortem testing of cattle herds is required for disease surveillance and control , due to the asymptomatic nature of the infection . - pubmed
METHODS : Patients with moderately severe UC , in remission , were randomized to MBSR or time / attention control . - pubmed
In a second experiment , macaques were given GSK744 LA 1 week before virus administration and challenged repeatedly until infection occurred . - pubmed
CONCLUSION : In clinical practice , platinum / fluoropyrimidines with adequate treatment duration is recommended for stage II / III gastric cancer patients according to the 7(th ) edition of the AJCC staging system after curative gastrectomy even with limited lymphadenectomy . - pubmed
METHODS : We tested two groups of women , screened using the Autism Spectrum Quotient - Group 1 : n = 415 women with ASC ( mean age 36.39 + - 11.98 years ) ; and Group 2 : n = 415 controls ( mean age 39.96 + - 11.92 years ) . - pubmed
We proposed to evaluate the association between serum indirect bilirubin levels and liver fibrosis in patients with chronic hepatitis C ( CHC ) genotype 1b . - pubmed
Biopsy proven CHC genotype 1b patients ' demographics , clinical and histopathological characteristics were evaluated . - pubmed
Logistic regression analysis was done to evaluate the clinical , laboratory and demographic features of the histologically proven liver fibrosis in CHC patients . - pubmed
A total of 112 biopsy proven CHC genotype 1b patients were enrolled into the study . - pubmed
Liver fibrosis scores were measured by using Ishak fibrosis scores and were divided into two groups ; fibrosis scores & lt;= 2 were categorized as mild fibrosis , 82 patients ( 73.2 % ) , whereas fibrosis scores & gt;2 were categorized as advanced fibrosis group , 30 patients ( 26.8 % ) . - pubmed
Patients with advanced fibrosis had lower indirect bilirubin levels than the mild fibrosis group ( 0.28 + - 0.02 mg / dl vs. 0.44 + - 0.032 mg / dl , p<0.001 , respectively ) . - pubmed
METHODS : Immunohistochemical analysis was carried out retrospectively on tumor samples from patients treated for bladder cancer . - pubmed
In the 1st study , 1,207 youth ( 685 girls ) ages 7 to 18 completed the R - SCS - C as well as measures of imaginary audience , anxiety , depression , and positive and negative affect . - pubmed
Long - term comparison of GOS - E scores in patients treated with phenytoin or levetiracetam for posttraumatic seizure prophylaxis after traumatic brain injury . - pubmed
Patients were identified by cross - referencing a list of patients receiving LEV or PHT , with a list of patients with ICD-9 code consistent with TBI . - pubmed
CONCLUSIONS : Long - term functional outcome in patients who experienced a TBI was not affected by treatment with PHT or LEV ; however , patients treated with PHT had a higher incidence of fever during hospitalization . - pubmed
Complement alternative pathway activation in human nonalcoholic steatohepatitis . - pubmed
Recently we reported complement activation in human NASH . - pubmed
Here , alternative pathway components were investigated in liver biopsies of obese subjects with healthy livers ( n = 10 ) or with NASH ( n = 12 ) using quantitative PCR , Western blotting , and immunofluorescence staining . - pubmed
Comparisons were made between tinnitus and non - tinnitus side of patients and normal ears of controls . - pubmed
Aryl organophosphate flame retardants induced cardiotoxicity during zebrafish embryogenesis : by disturbing expression of the transcriptional regulators . - pubmed
Because a previous study reported that two aryl - OPFRs induced cardiotoxicity during zebrafish embryogenesis , we designed experiments to compare the heart developmental toxicity of a series of aryl - OPFRs with alkyl - OPFRs and explored possible internal mechanism . - pubmed
First , acute toxicity of 9 frequently used OPFRs were studied with zebrafish embryos ( 2 - 96 hpf ) . - pubmed
In clinical islet transplantation , allogeneic islets of Langerhans are transplanted into the portal vein of patients with type 1 diabetes , enabling the restoration of normoglycemia . - pubmed
Composition of human faecal microbiota in resistance to Campylobacter infection . - pubmed
In mice , specific species composition of gut microbiota enhances susceptibility to Campylobacter jejuni but little is known about the specific composition of the human gut microbiota in providing protection from infections caused by enteropathogens . - pubmed
Species composition of human gut microbiota is important for colonization resistance to Campylobacter infection . - pubmed
Increased Nonalternans Repolarization Variability Precedes Ventricular Tachycardia Onset in Patients with Implantable Defibrillators . - pubmed
This study was conducted to determine if NARV increases prior to VT in patients with implantable cardioverter defibrillators ( ICDs ) . - pubmed
METHODS : TWA and NARV were calculated from shock - channel electrograms preceding onset of VT or non - VT events in patients with an ICD . - pubmed
In each patient , presence of both a VT and a non - VT event with the same QRS morphology before the event was required . - pubmed
RESULTS : Before the disease episode , hair T3 levels differed significantly between F - MDD patients and HC . - pubmed
In the disease episode , hair T3 levels differed significantly between F - MDD or R - MDD patients and HC ; and hair T4 levels differed significantly between R - MDD patients and HC . - pubmed
Hair T3 levels significantly negative correlated with HAMD scores in F - MDD patients . - pubmed
METHODS : Patients with PsA were monitored in a prospective , observational study . - pubmed
We investigated the effect of an acute experimental stress ( impending Trier Social Stress Task in the morning ) on pre - sleep measures of cortisol and autonomic arousal in perimenopausal women with and without insomnia that developed in the context of the menopausal transition . - pubmed
Following adaptation to the laboratory , twenty two women with ( age : 50.4 + - 3.2 years ) and eighteen women without ( age : 48.5 + - 2.3 years ) insomnia had two randomized in - lab overnight recordings : baseline and stress nights . - pubmed
These results show that pre - sleep stress impacts autonomic nervous system functioning before and during sleep in perimenopausal women with and without insomnia . - pubmed
The aim of this study was to investigate the effect of carnosine ( CAR ) alone and together with vitamin E ( Vit E ) on alcoholic steatohepatitis ( ASH ) in rats . - pubmed
During structured interviews , we examined the co - occurrence of headaches and epilepsy in children and their families : ( 1 ) 172 children from the headache clinic , were questioned for the number and type of epileptic seizures and epilepsy diagnosis . - pubmed
( 2 ) Around 70 children from the epilepsy clinic for the frequency and type of headaches and headache syndrome diagnosis . - pubmed
( 3 ) A total of 149 parents of children with benign childhood epilepsy with centro - temporal spikes ( BCECTS ) and childhood absence epilepsy ( CAE ) , for the relative frequency of headaches in first- and second - degree relatives . - pubmed
RESULTS : Out of 172 , 84 ( 48.8 % ) children with headache had a migraine and 60 ( 34.9 % ) had tension headaches ; 3 children ( 1.7 % ) had epilepsy or unprovoked seizures . - pubmed
Eight out of 70 patients with epilepsy had headaches ( 11.4 % ) ; none had migraine . - pubmed
Around 43 % of patients with BCECTS or CAE had a family history of headache , more prevalent in first - degree relatives of children with BCECTS than CAE . - pubmed
Family history of headache was frequent in patients with BCECTS and CAE , without any significant difference between the two . - pubmed
The larval stages of the cestodes Echinococcus multilocularis and Echinococcus granulosus cause the important zoonoses known as larval echinococcoses . - pubmed
This was a case - control study included 60 ( AIS ) cases , and 100 healthy children with comparable age and gender as control group . - pubmed
Twelve hours after last injection , rats were killed by decapitation and brain areas were rapidly isolated . - pubmed
Autologous hematopoietic cell transplantation ( AHCT ) is standard therapy for eligible patients with multiple myeloma . - pubmed
Mycobacterium tuberculosis causes tuberculosis ( TB ) , a disease that killed more than 1.5 million people worldwide in 2014 , and the Bacillus Calmette Guerin ( BCG ) vaccine is the only currently available vaccine against TB . - pubmed
CONCLUSIONS : Phalangeal QUS appeared a useful tool to evaluate bone quality in BC women on AIs . - pubmed
METHODS : Between 2007 and 2014 , 14 patients ( mean age 39 years ) with suspected penile fracture underwent US examinations . - pubmed
RESULTS : The most common blunt injury to the penis that occurred in nine patients was penile fracture due to rupture of the corpus cavernosum . - pubmed
Four patients presented an injury to the subtunical venous plexus in the absence of complete tunical disruption . - pubmed
One patient had urethral rupture with inability to urinate and apparent urethrorrhagia . - pubmed
PURPOSE : Development of metastasis in patients with breast cancer ( BC ) is the most important negative prognostic factor and this process mainly begins with lymphatic involvement . - pubmed
The purpose of this study was to investigate if laterality is an independent prognostic factor for metastasis in N3 breast cancer patients . - pubmed
Patients with left BC had significantly higher rate of axial bone metastases compared with the right BC group ( 55.7 vs 35.8 % , p<0.02 , respectively ) . - pubmed
Median OS did not differ between the groups , however , there was a trend towards lower OS in patients with left BC ( p=0.68 ) . - pubmed
A 66 - year - old man who presented with coma was found to have isolated severe hyperammonemia and diagnosed with a late - onset urea - cycle disorder . - pubmed
However , these results support the concept of directly modifying peripheral blood as a novel approach to conveniently treat articular cartilage lesions in patients . - pubmed
One - hundred and thirty - six ( 40 % ) , 122 ( 35 % ) , and 85 ( 25 % ) patients had normal coronary arteries , single - vessel CAD , and multivessel CAD , respectively . - pubmed
Development of a qualitative assay for screening of Bordetella pertussis isolates for pertussis toxin production . - pubmed
We analyzed 30 samples of middle - ear mucosa in patients affected by chronic suppurative otitis media with ear drum perforation with / without cholesteatoma and otosclerosis as control . - pubmed
This new combination therapy may lead to more effective disease eradication , especially in patients at high risk of TKI resistance and disease progression . - pubmed
This study demonstrates that a KD extends longevity and healthspan in mice . - pubmed
BACKGROUND : The prevalence and significance of right ventricular dysfunction ( RVD ) in patients with cardiogenic shock due to acute myocardial infarction ( AMI - CS ) have not been well characterized . - pubmed
In the SHOCK trial and registry , respectively , 38 % and 37 % of patients had RVD , but RVD was not associated with 30 - day or 6 - month survival ( hazard ratio [ HR ] 1.51 , ( 99 % CI 0.92 - 2.49 ; P = .10 ) . - pubmed
Routine assessment with pulmonary artery catherization allows detection of RVD ; however , further work is needed to identify interventions that will result in improved outcomes for these patients . - pubmed
Based on this novel strategy , we successfully detected miR-141 , a promising biomarker for human prostate cancer , with high selectivity . - pubmed
STUDY DESIGN : A retrospective analysis of a prospectively collected data of adult spinal deformity patients was carried out . - pubmed
Compliance with an Enhanced Recovery After a Surgery Program for Patients Undergoing Gastrectomy for Gastric Carcinoma : A Phase 2 Study . - pubmed
METHODS : This phase 2 study enrolled 168 patients undergoing elective gastrectomy for gastric carcinoma . - pubmed
Therefore , the aim of this study is to investigate the effect of solution volume on the detection rate of a salivagram in patients with brain lesion , and to determine the optimal solution volume of salivagram . - pubmed
We retrospectively reviewed clinical data and solution volume of radionuclide used in the salivagram of 77 patients with dysphagia , and the patients were divided into 2 groups according to the solution volume of the radionuclide ( Group A-0.1 mL vs Group B-0.5 mL ) . - pubmed
Even a small difference of the solution volume of radionuclide in salivagram can affect the detection rate of salivary aspiration in patients with brain lesion . - pubmed
Both of them were comparable to the first - line anti - TB agents INH and RIF against MTB H37Rv , and were far more potent than INH and RIF against MDR - TB 16833 and 16995 strains . - pubmed
Alzheimer ' s disease ( AD ) is a well - known neurodegenerative disorder affecting millions of old people worldwide and the corresponding epidemiological data highlights the significance of the disease . - pubmed
HIV-1 transmission is usually initiated by a single viral strain called transmitted/ founder ( T / F ) virus . - pubmed
In in vitro models , HIV-1 can efficiently spread via cell - free and virological synapse ( VS)-mediated cell - to - cell infection . - pubmed
These compounds isolated from Tetradium plants exhibit a wide range of biological activities in vitro and in vivo including antitumor , antibacterial , anti - inflammatory , insecticide , cardioprotective and lipid - lowering , treating CNS disorders , digestive system regulation and endocrine system improving activities . - pubmed
Emergence of methicilin resistant Staphylococcus aureus ( MRSA ) strains is a major cause of infirmity worldwide and has limited our therapeutic options against these pathogens . - pubmed
After 24 h , Methicillin - resistant Sthaphylococcus aureus ( MRSA ) strains showed fluoxetine MICs equal to 64 mug / mL and 128 mug / mL , respectively . - pubmed
Anti - oxidant and anti - inflamatuar effectiveness of caftaric acid on gastric ulcer induced by indomethacin in rats . - pubmed
As a result of our study , caftaric acid showed anti - oxidant and anti - inflammatory effects in indomethacin - induced gastric ulcer in rats . - pubmed
PATIENTS AND METHODS : In all , 21 patients with localized prostate cancer were treated with a RR for 3DCRT in 40 x 2 Gy . - pubmed
The patient tolerance and acute rectal toxicity were surveyed during radiotherapy using Common Terminology Criteria for Adverse Events ( CTCAE ) v.4.0 . - pubmed
RESULTS : Patients tolerated the RR well during 20 fractions with mild degree of anal irritation . - pubmed
Finally , AdoCbl alleviates deficits in dopamine release sustainability caused by LRRK2 disease variants in mouse models . - pubmed
This is a case report of sinonasal and orbital Ewing ' s sarcoma in a 24 - year - old male patient who presented with a history of right nasal obstruction , right eye pain and periorbital edema . - pubmed
Potentially pathogenic strains of non-01 V. - pubmed
Monitoring of Neutrophil Recruitment to Mice Lungs During Pneumonic Plague . - pubmed
with the plague bacterium Yersinia pestis to study in vivo neutrophil responses to the infection . - pubmed
Patients with advanced EBDC often experience biliary obstruction , which can lead to jaundice and progress to death . - pubmed
Observations : A 35 - year - old woman presented during the third trimester of pregnancy with bilateral uncontrolled primary open angle glaucoma . - pubmed
marinoi , demonstrating that several strains ( Arenibacter algicola strain SMS7 , Marinobacter salarius strain SMR5 , Sphingorhabdus flavimaris strain SMR4y , Sulfitobacter pseudonitzschiae strain SMR1 , Yoonia vestfoldensis strain SMR4r and Roseovarius mucosus strain SMR3 ) stimulate growth of the diatom partner . - pubmed
OBJECTIVES : This study sought to evaluate the association between contrast - enhanced multidetector computed tomography ( CE - MDCT ) attenuation and local epicardial conduction speed ( ECS ) and electrographic abnormalities in patients with arrhythmogenic right ventricular cardiomyopathy ( ARVC ) and ventricular tachycardia ( VT ) . - pubmed
METHODS : Patients with ARVC who underwent CE - MDCT followed by endocardial ( n = 30 ) and epicardial ( n = 21 ) electroanatomical mapping ( EAM ) and VT ablation were prospectively enrolled . - pubmed
Regions with low attenuation likely reflect fibro - fatty involvement in the RV and may serve as important VT substrates in patients with ARVC who are undergoing VT ablation . - pubmed
Efficacy of a brief mindfulness intervention upon anxiety in early psychosis patients . - pubmed
METHODS : Our study included patients who had experienced an initial episode of psychosis , with less than 30 months of antipsychotic exposure . - pubmed
CONCLUSIONS : A brief mindfulness exercise , conducted in a routine office visit , produced a significant reduction in state anxiety for early psychosis patients , regardless of symptom burden . - pubmed
A wearable resistive strain sensor that can quickly and precisely detect human motions like finger bending was fabricated by a 3D printed hydrogel film . - pubmed
The study model was based on a PC12 cell line , derived from the pheochromocytoma of a rat adrenal medulla , cultured in RPMI 1640 . - pubmed
Intratracheal injection of nitric oxide , generated from air by pulsed electrical discharge , for the treatment of pulmonary hypertension in awake ambulatory lambs . - pubmed
RESULTS : In awake lambs with acute pulmonary hypertension , NO was continuously delivered via the Scoop catheter at 400 ml / min . - pubmed
CONCLUSIONS : Continuously delivering electrically generated NO through a Scoop catheter produces vasodilation of the pulmonary vasculature of awake lambs with pulmonary hypertension . - pubmed
Transtracheal NO delivery may provide a long - term treatment for patients with chronic pulmonary hypertension as an outpatient without requiring a mask or tracheal intubation . - pubmed
The incidence , risk factors , and long - term outcomes of acute kidney injury in hospitalized diabetic ketoacidosis patients . - pubmed
The current study aimed to investigate the incidence rate , risk factors , long - term renal outcomes , and mortality in DKA patients with AKI . - pubmed
METHODS : A total of 179 patients diagnosed with DKA at Sun Yat - sen Memorial Hospital from January 2012 to January 2018 were included in the analysis . - pubmed
RESULTS : Among 179 DKA patients , 98 patients ( 54.75 % ) were diagnosed as AKI . - pubmed
During follow - up , DKA patients with AKI showed more than a two - fold decline in eGFR within 1 year after discharge from the hospital when compared with non - AKI DKA patients . - pubmed
CONCLUSIONS : Multiple risk factors contribute to the development of AKI in DKA patients . - pubmed
AKI and advanced AKI stage are associated with rapid progressive CKD and long - term mortality in patients with DKA . - pubmed
Methods : The study included 539 patients in total , of which 443 had primary prostate carcinoma and 96 patients had benign prostatic hyperplasia ( BPH ) . - pubmed
Background : Fluoxetine ( FLU ) is the first - line and widely used medication for depression ; however , FLU treatment is almost ineffective in 30%-40 % of patients with depression . - pubmed
Methods : The chronic unpredictable mild stress ( CUMS ) rat model was used to simulate depression . - pubmed
Sacubitril / valsartan reduces mortality in heart failure with reduced ejection fraction ( HFrEF ) patients , partially due to cardiac reverse remodeling ( RR ) . - pubmed
We sought to evaluate the rates of left ventricle ( LV ) and left atrial ( LA ) RR through standard and advanced echocardiographic imaging in a cohort of HFrEF patients , after the introduction of sacubitril / valsartan . - pubmed
We analyzed 77 patients ( 65 + - 11 years old , 78 % males , 40 % ischemic etiology ) with 76 ( 28 - 165 ) months since HFrEF diagnosis . - pubmed
In HFrEF patients , despite a long history of the disease , the introduction of sacubitril / valsartan provides a rapid global ( i.e. - pubmed
BACKGROUND : Cognitive function may change over time in patients with SLE , and cognitive function trajectories have not well been studied . - pubmed
METHODS : Residual cytologic fixatives ( n = 42 ) from 39 patients who underwent EUS - FNA for pancreatic lesions were collected along with demographics , imaging , and laboratory studies . - pubmed
The comparison between pulmonary rehabilitation with music therapy and pulmonary rehabilitation alone on respiratory drive , cortisol level and asthma control in patients hospitalized with asthma exacerbation . - pubmed
The objective of this interventional double - blinded randomised controlled trial was to assess whether music therapy , as a complementary modality to pulmonary rehabilitation , can help to improve respiratory drive , asthma control and quality of life in patients with asthma exacerbation . - pubmed
METHODS : Hospitalized patients with asthma exacerbation enrolled in the study were randomly assigned to experimental ( music therapy ) or control ( popular science programme ) group . - pubmed
Convalescent plasma has been used to treat a number of infections during pandemics , including severe acute respiratory syndrome coronavirus ( SARS - CoV ) , Middle Eastern respiratory syndrome coronavirus ( MERS - CoV ) and now severe acute respiratory syndrome coronavirus-2 ( SARS - CoV-2 ) . - pubmed
SOURCES : A review of articles published in PubMed was performed on 13 July 2020 to summarize the currently available evidence in human studies for convalescent plasma as a treatment for coronaviruses . - pubmed
CONTENT : There were sixteen COVID-19 , four MERS and five SARS reports describing convalescent plasma use in humans . - pubmed
Adequate treatment options for patients with advanced HCC are currently limited . - pubmed
In vitro cultures of primary human airway epithelial cells ( hAECs ) grown at air - liquid interface have become a valuable tool to study airway biology under normal and pathologic conditions , and for drug discovery in lung diseases such as cystic fibrosis ( CF ) . - pubmed
The study aims to investigate the effects of COVID-19 infection with asymptomatic and mild symptoms on trans - myocardial repolarization parameters in children without treatment . - pubmed
DESIGN : Six human tibia plateaus ( 2 healthy , 2 with osteoarthritis , and 2 with posttraumatic osteoarthritis ) were used for full - depth cartilage sampling systematically across the joint surface at 12 medial and 4 lateral sites . - pubmed
Four studies focussed on human T - cell lymphotropic virus type 1 ( HTLV-1 ) , three studies on Ebola , and one study on influenza vaccination . - pubmed
The potential ability of multi - differentiation and paracrine function of MSCs is bringing new hope to patients with male infertility . - pubmed
ABSTRACT : We describe functional and anatomical imaging findings in an 86 - year - old woman who was treated for paroxysmal atrial fibrillation 5 years ago with radiofrequency ablation . - pubmed
Ultrastructural features of degenerated cardiac muscle cells in patients with cardiac hypertrophy . - pubmed
Degenerated cardiac muscle cells were present in hypertrophied ventricular muscle obtained at operation from 12 ( 38 % ) of 32 patients with asymmetric septal hypertrophy ( hypertrophic cardiomyopathy ) or aortic valvular disease . - pubmed
These observations suggest that degenerated cardiac muscle cells have poor contractile function and may be responsible for impaired cardiac performance in some patients with chronic ventricular hypertrophy . - pubmed
[ Effect of cyclophosphamide on experimental tuberculosis in mice ] . - pubmed
This clinical use of Gelfoam for temporary rehabilitation is indicated in : 1 ) situations in which paralysis may be temporary , 2 ) patients for whom an open operative procedure must be delayed , and 3 ) circumstances in which it is desirable to determine the effect of vocal cord injection prior to placement of nonabsorbable material . - pubmed
The use of blood and blood products for resuscitation of burn patients is of primary importance in burn patients . - pubmed
The extent of corneal destruction in rabbit corneas infected with live Pseudomonas cells was significantly greater in eyes treated with zinc sulfate than in controls , precluding its use in a clinical setting . - pubmed
[ Diagnosis of chronic cholecystitis in children ] . - pubmed
[ State of free amino acid metabolism in children with chronic liver diseases ] . - pubmed
Garlic in alloxan - induced diabetic rabbits . - pubmed
Optimal stimulation of paralyzed muscle after human spinal cord injury . - pubmed
Influence of biological variations and sample handling on measured microalbuminuria in diabetic patients . - pubmed
This assay has proven to be valuable for determining the presence of HCV in various samples ; furthermore , it offers the possibility of diagnosis of HCV infection in seronegative patients . - pubmed
None of these patients experienced metastases . - pubmed
Five of these patients had distant metastases ( P less than 0.02 ) within 2 years of treatment . - pubmed
For those patients at low risk for relapse , the mean G0 is calculated to be 22.5 , and 13.6 weeks for those who have relapsed or are at high risk for relapse . - pubmed
Computed tomography of the brain in the evaluation of the headache patient . - pubmed
A retrospective analysis was conducted of 100 consecutive patients evaluated with computerized tomography of the head who had the chief complaint of headache . - pubmed
, as well as from L1210 ( murine leukemia ) mouse cells was investigated utilizing the technique of the alkaline unwinding of the double stranded DNA molecule . - pubmed
However , the variability in infarct size tended to be greater ( P = 0.0647 ) among all hyperglycemic cats compared to control animals . - pubmed
Retinal detachments were produced in domestic cats by injecting fluid between the retinal pigment epithelium and neural retina . - pubmed
Subcutaneous instead of intraperitoneal infection with T. - pubmed
A patient was evaluated because of edema , pruritus and generalized painless lymphadenopathy . - pubmed
Once he was stable , a laparotomy was performed and the patient died two days later because of septic shock . - pubmed
Construction of viable deletion and insertion mutants of the Sabin strain of type 1 poliovirus : function of the 5 ' noncoding sequence in viral replication . - pubmed
A number of deletion and insertion sequences were introduced into the 5 ' noncoding sequence ( 742 nucleotides long ) of the genome of the Sabin strain of type 1 poliovirus by using an infectious cDNA clone of the virus strain . - pubmed
A 42 - year - old man with adult - onset type III glycogenosis ( Cori ' s disease ) developed a gradually progressive polyneuropathy with markedly reduced activity of muscle amylo-1,6 - glucosidase and glycogen accumulation within all elements of biopsied sural nerve , including axons , as shown by ultrastructural assessment . - pubmed
Western blots , using sera from five patients with mucormycosis , consistently identified five different determinants in the R. - pubmed
This suggests that several of the Rhizopus antigens are present during mucormycosis . - pubmed
Enzyme - linked immunosorbent assays of sera from five patients with mucormycosis and with rabbit antisera resulted in antibody titers ranging from 1:64 to 1:32,000 for the R. - pubmed
37 patients with muscle disease ( 23 myopathies and 14 neurogenic muscle diseases ) were studied by spiroergometric investigations . - pubmed
[ Chronic subdural hematoma in patients over 70 ] . - pubmed
Suppression of annual plasma testosterone and thyroxine cycles in the edible dormouse Glis glis under constant photoperiod at 24 degrees C. Exposure of male edible dormice all year round to an unvarying photoperiod and warm temperature disrupted their biological cycles ; hibernation was almost completely suppressed , and short lived infradian cycles of body weight , and of plasma testosterone and thyroxine were measured instead of the normal annual pattern . - pubmed
Vascular reactivity to noradrenaline and 5 - hydroxytryptamine in hypertensive rats . - pubmed
[ Changes in the water and electrolyte content of the blood and muscles in patients with shock phenomena ] . - pubmed
[ Radiological picture of acute appendicitis in children ] . - pubmed
In subgroup 1 ( 40 patients ) , episodes of non - exertional angina were associated with a pattern of hyperacute subepicardial injury and , frequently , with ventricular arrhythmias . - pubmed
Of these patients , 25 % developed a myocardial infarction shortly after admission . - pubmed
Only 5 % of patients in this subgroup developed a myocardial infarction during their hospital stay . - pubmed
It is concluded that : ( 1 ) observation of the electrocardiogram during spontaneous angina in patients with known atherosclerotic coronary heart disease may be of prognostic significance and may influence therapeutic decision . - pubmed
A total of 91 multiply resistant bacterial strains , including Klebsiella pneumoniae ( 32 strains ) , Pseudomonas aeruginosa ( 16 strains ) , and Serratia marcescens ( 43 strains ) , were collected during hospital epidemics of nosocomial infection from 1975 to 1979 . - pubmed
Both Klebsiella pneumoniae and Serratia marcescens , including multiply resistant and non - multiply resistant strains , were most susceptible to the 1 - oxa - beta - lactam LY127935 and cefotaxime . - pubmed
All three new beta - lactams were active against non - multiply resistant strains of Escherichia coli , Enterobacter spp . , Proteus spp . - pubmed
This belief has persisted despite frequent complaints from patients with glaucoma that their central vision is disturbed . - pubmed
Seventy - eight percent of patients with early glaucomatous visual field defects were found to have a defect in color perception when tested with a desaturated D-15 color panel that tests only the central 1.5 degrees . - pubmed
Spatial contrast sensitivity appears to be reduced in patients with glaucoma . - pubmed
Indium-111 - labelled human platelets : a method for use in severe thrombocytopenia . - pubmed
We describe and evaluate a simple method for labelling autologous human platelets with Indium-111 - oxine in patients with severe thrombocytopenia . - pubmed
Twenty patients with immune thrombocytopenia and platelet counts ranging from 5 to 119 X 10(9)/1 were investigated . - pubmed
This method permits quantitative platelet imaging with autologous labelled platelets in patients with severe thrombocytopenia . - pubmed
Acute surgical abdomen caused by thrombocytopenia in patients with acute leukemia and multiple myeloma . - pubmed
One patient with multiple myeloma and four patients with acute leukemia presented with severe abdominal pain . - pubmed
Severe thrombocytopenia was found in all patients . - pubmed
Laparotomy was performed in the patient with multiple myeloma , and revealed numerous petechiae throughout the peritoneum . - pubmed
All five patients responded to platelet transfusions with disappearance of the abdominal signs and symptoms . - pubmed
Severe thrombocytopenia should be considered among the causes of acute surgical abdomen in patients with malignant hematological disorders , and platelet transfusions should be administered before any surgical intervention . - pubmed
Experimental infection in rabbits evoked by Pseudomonas aeruginosa , Proteus mirabilis , Escherichia coli and Klebsiella pneumoniae treated with gentamicin , amikacin and sisomicin . - pubmed
Rabbits were infected with freshly isolated strains of Ps . - pubmed
[ The changes on plasma aldosterone concentration during acute respiratory acidosis in dogs . - pubmed
with a mouse - adapted strain of dengue virus ( DV ) , the following differences were noted in the course of infection . - pubmed
It is suggested from these data that the course of DV infection in mice is affected by the availability of thymus - derived lymphocytes ( T - cells ) . - pubmed
The long - term antihypertensive efficacy and tolerability of a fixed combination of oxprenolol 160 mg slow - release + chlortalidone 20 mg was studied in 40 out - patients with mild to moderate essential hypertension followed during one year with monthly clinical visits . - pubmed
Results confirm that the fixed combination of oxprenolol 160 mg slow - release + chlorthalidone 20 mg is able to long term control mild to moderate hypertension with a good tolerability , thus allowing an improved patient compliance . - pubmed
A noninvasive , zero heat flux method of determining core ( intracardiac blood ) temperature was studied in ten anesthetized patients having whole body hyperthermia for the treatment of cancer . - pubmed
Over fifty patients with severe head injury , and one hundred with stroke , have now been treated with the competitive NMDA antagonist CGS 19755 ( selfotel ) . - pubmed
For stroke , however , the maximal tolerated dose was 1.5 mg / kg , because these conscious patients developed hallucinations and agitation . - pubmed
By extrapolating from animal studies the " best estimate " would be around 5 mg / kg in patients with severe head trauma . - pubmed
Although several NMDA antagonists , including CGS 19755 ( selfotel ) , are currently entering efficacy trials for stroke , based upon their tremendous potency in animal models , the problem of psychomimetic effects may necessitate the use of additional management strategies , e.g. - pubmed
No cyclosporin - induced chromosomal aberrations in human peripheral blood lymphocytes in vitro . - pubmed
Continuous in vitro treatment of human peripheral blood lymphocytes with cyclosporin A for 20 h and 44 h in the absence of metabolic activation decreased the mitotic index in a concentration - dependent way ( MI about 35 % at 50 micrograms / ml ) . - pubmed
During the past decade , considerable evidence has accrued regarding the immunologic uniqueness of human milk and of the important role that the immune system in human milk plays in protecting not only the mature , healthy newborn , but also the premature infant who is more prone to infections and the damage caused by inflammatory processes . - pubmed
However , there is a great deal more to learn about the prophylactic and therapeutic uses of human milk in low birth weight infants , including ( 1 ) the status of many of the host defense factors in preterm milk , ( 2 ) how to preserve the protective agents in human milk during processing and storage , ( 3 ) the dose and duration of treatment with human preterm or mature milk that will be needed to protect against a particular disorder , ( 4 ) whether non - maternal milk is as efficacious as maternal milk for these infants , and ( 5 ) in view of the concern of potential graft versus host reactions , whether it is desirable or contraindicated to maintain the leukocytes in human milk used to feed premature infants . - pubmed
The biochemical basis of peritoneal cell cytotoxicity for Cryptococcus neoformans was studied by measuring the killing of the yeast by peritoneal resident cells and peritoneal exudate cells obtained from normal and proteose - peptone - injected animals , respectively . - pubmed
All the children had a huge abdominal mass but none of them had complete intestinal obstruction . - pubmed
Development of endometrial cancer in women on estrogen and progestin hormone replacement therapy . - pubmed
The presenting symptoms , hormonal regimens , treatment modalities , tumor pathology , and follow - up of 25 women developing endometrial cancer while receiving postmenopausal estrogen and progestin therapy were investigated retrospectively . - pubmed
Estrogen and progestin therapy does not prevent endometrial cancer in all patients . - pubmed
Women who developed this tumor on sequential therapy in general received less than the recommended guidelines for daily dosage and monthly duration of progestin . - pubmed
Following a report of the efficacy of total lymphoid irradiation ( TLI ) in the treatment of chronic progressive multiple sclerosis a further randomised double - blind placebo - controlled study was undertaken with the intention of entering 56 patients . - pubmed
It was noteworthy that MCZ was effective for the treatment of deep seated mycosis and significant effective rate was obtained in the group of patients who had neutrophils and lymphocytes less than 500 / microliters . - pubmed
SUBJECTS : 468 survivors of an acute myocardial infarction ( 289 men and 178 women ) aged 31 - 92 . - pubmed
We hypothesize , based on the similar localization of flavin and that of iron reduction , that the accumulation of riboflavin sulfates induced by iron deficiency may be an integral part of the turbo iron - reducing system in sugar beet roots . - pubmed
Distribution of body water in patients with cirrhosis : the effect of liver transplantation . - pubmed
We compared total body water and intracellular - extracellular distribution of body water between male patients with mild liver disease without ascites ( n = 9 ) , male patients with severe liver disease and gross ascites ( n = 6 ) and a group of age- , sex- , height- and weight- matched controls ( n = 6 ) . - pubmed
We saw no significant difference in total body water between the healthy controls , patients without ascites and patients with ascites ( 46.5 + /- 9.2 kg , 45.4 + /- 6.6 kg and 50.4 + /- 5.1 kg , respectively ) , although , as expected , extracellular water was increased in patients with ascites compared with healthy controls and cirrhotic patients without ascites ( 36.9 + /- 6.5 kg vs. 25.4 + /- 4.4 kg , p = 0.005 ; and 36.9 + /- 6.5 kg vs. 27.0 + /- 5.3 kg , p = 0.002 , respectively ) . - pubmed
However , intracellular water was significantly reduced in patients with severe liver disease compared with that in controls ( 13.6 + /- 3.3 kg vs. 21.5 + /- 4.2 kg , p = 0.005 ) or patients without ascites ( 13.6 + /- 3.3 kg vs. 18.3 + /- 2.9 kg , p = 0.01 ) . - pubmed
A 60 - year - old female patient presenting with anemia was found to have a left - sided renal tumor and a contralateral adrenal mass of 2 cm in diameter . - pubmed
The case illustrates that surgery of solitary metastases from renal cell carcinoma may be beneficial to the patient . - pubmed
METHODS : Twenty - two healthy , slightly overweight , sedentary , normotensive , normolipemic men , age 22 to 44 years , were randomly assigned to an exercise or control group for 12 weeks followed by a 4 - week washout period . - pubmed
The case presented is an example of an acute gastric volvulus in a 2 - year - old male child affected by a diaphragmatic defect The peculiar aspect of this case consists in the age of arousal being more usual in an earlier age An appropriate surgical treatment has permitted the patient 's recovery . - pubmed
Mechanisms of selective motor neuron death in ALS : insights from transgenic mouse models of motor neuron disease . - pubmed
Concerning the mechanism(s ) of disease underlying amyotrophic lateral sclerosis ( ALS ) , transgenic mouse models have provided ( i ) a detailed look at the pathogenic progression of disease , ( ii ) a tool for testing hypotheses concerning the mechanism of neuronal death , and ( iii ) a host appropriate for testing therapeutic strategies . - pubmed
Diversion - related experimental colitis in rats . - pubmed
The aim of the present study was to create an experimental model of diversion - related colitis in rats , so in the future it will be possible to test different hypotheses . - pubmed
RESULTS : Exclusion was associated with vascular congestion , a decrease in length of glandular crypts ( P & lt ; 0.01 ) , and an erosion of surface epithelium ; inflammation of the mucosa was absent in all control animals and present in all test animals . - pubmed
CONCLUSION : This experimental model of diversion colitis is characterized by histologic and bacteriologic modifications comparable with those reported in humans but with different histochemical changes . - pubmed
We therefore compared the effects of daily variations in particles of different sizes on peak expiratory flow ( PEF ) during a 57 - day follow - up of 39 asthmatic children aged 7 - 12 years . - pubmed
Women with silicone gel - filled breast implants ( SBIs ) are likely to be at a slightly higher risk of developing an autoimmune - like syndrome . - pubmed
RESULTS AND CONCLUSIONS : Cross sectional study : In the 73 children aged 3 years who attended nursery schools , 7 cases of enuresis ( 9.6 % ) were identified . - pubmed
Visual - induced postural sway in children with and without otitis media . - pubmed
Children with otitis media with effusion ( OME ) have been shown to have a significantly higher velocity of sway than normal children . - pubmed
Further studies are needed to define the role of vestibular function in the management of children with OME . - pubmed
We report about 38 patients aged between 1 and 19 years ( 36.8 % female , 63.2 % male ; mean age 7.8 years ) admitted as inpatients for further neurorehabilitation mostly 4 weeks after severe acquired brain injury ( ABI ) of different aetiology . - pubmed
Dietary supplementation of deficient substrates ( arachidonic acid or myo - inositol ) , either in vitro or in vivo , has been shown to reduce the incidence of diabetes - related malformations in offspring of diabetic pregnant animals . - pubmed
We determined the prevalence of rheumatoid nodules of finger tendons in patients with RA , using high frequency linear transducers with high resolution ultrasonography . - pubmed
METHODS : The study comprised 54 consecutive patients with RA and 20 controls . - pubmed
All 25 patients studied became culture - negative within 2 months of initiation of therapy for tuberculosis and remained negative for a median of 13 months follow - up after completion of therapy . - pubmed
In summary , the concomitant use of rifabutin and HAART can lead to successful treatment of HIV - infected patients with tuberculosis without increased side effects . - pubmed
Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease : the ADMIT study : A randomized trial . - pubmed
OBJECTIVE : To determine the efficacy and safety of lipid - modifying dosages of niacin in patients with diabetes . - pubmed
PARTICIPANTS : A total of 468 participants , including 125 with diabetes , who had diagnosed peripheral arterial disease . - pubmed
INTERVENTIONS : After an active run - in period , participants were randomly assigned to receive niacin ( crystalline nicotinic acid ) , 3000 mg / d or maximum tolerated dosage ( n = 64 with diabetes ; n = 173 without diabetes ) , or placebo ( n = 61 with diabetes ; n = 170 without diabetes ) for up to 60 weeks ( 12 - week active run - in and 48 - week double - blind ) . - pubmed
After sterility testing and quantity analysis of the residual contrast in 28 vials , this method was successfully used in 10 patients . - pubmed
Because macrocephaly could be a sign of abnormal brain development and because 30 % to 50 % of children with NF-1 display macrocephaly in the absence of hydrocephalus , we sought to determine the relationship between macrocephaly and other brain abnormalities in young subjects with NF-1 . - pubmed
These subjects were free of brain tumor , epilepsy , or other obvious neurologic problems . - pubmed
RESULTS : Cranial circumference was 2 or more SDs above the age norm in seven ( 39 % ) of 18 subjects , a frequency of macrocephaly 17 - fold higher than normal . - pubmed
Conventional MR imaging showed abnormalities in all 18 children , although there were more extensive abnormalities in subjects with macrocephaly . - pubmed
Use of Taenia crassiceps cysticercus antigen preparations for detection of antibodies in cerebrospinal fluid samples from patients with neurocysticercosis ( Taenia solium ) . - pubmed
Using immunoblotting of the three antigens , low - molecular - mass peptides ( 18 and 14 kDa ) were characterized only in cerebrospinal fluid samples from patients with neurocysticercosis . - pubmed
RESULTS : Both retroviral and adenoviral vector - mediated transduction of the dCK complementary DNA resulted in marked sensitization of tongue squamous carcinoma cell lines to the cytotoxic effects of cytarabine in vitro . - pubmed
Carriage rates for DCC children and controls were 58 and 37 % for S. - pubmed
METHODS : A 28 - year - old female presented with nodular scleritis in the right eye and left orbital inflammation lasting 1 year . - pubmed
The patient initially responded to systemic steroids , but then ocular inflammation became more severe , associated with onset of fever , myalgias , and elevation of the erythrocyte sedimentation rate , accompanied by formation of multiple cutaneous abscesses . - pubmed
RESULTS : The diagnosis of pyoderma gangrenosum was made 1 year after the occurrence of ocular symptomatology , when the patient presented with ocular and skin lesions and abscesses in the spleen and liver . - pubmed
Thromboembolic complications are often seen in patients with nephrotic syndrome . - pubmed
In these patients , there is evidence of endothelial cell injury and probably secondary activation of the coagulation cascade . - pubmed
Four of these compounds ( 2 - 5 ) exhibited moderate cytotoxicities against human colon carcinoma and human lung carcinoma cell lines with IC(50 ) 's ranging from 2 to 25 microg / mL. - pubmed
Epileptiform abnormalities in children with attention - deficit - hyperactivity disorder . - pubmed
Enhanced protection against the migratory phase , but defective protection against the intestinal phase of Strongyloides venezuelensis infection in cotton rats , Sigmodon hispidus . - pubmed
The protective capacity of the cotton rat , Sigmodon hispidus , against the migratory and intestinal phases of Strongyloides venezuelensis infection was examined . - pubmed
To determine whether this enhanced protection was expressed during the migratory phase or the intestinal phase , larval recovery from the lungs of cotton rat was evaluated 3 days after subcutaneous L(3 ) infection . - pubmed
For the study of the hepatitis E virus infection animal model , two chimpanzee were inoculated with hepatitis E virus . - pubmed
[ Laparoscopic and classic cholecystectomy in patients with liver cirrhosis ] . - pubmed
PATIENTS AND METHODS : Sixty seven patients with gallstones with well - documented cirrhosis undergoing cholecystectomy ( laparoscopic cholecystectomy ( LC ) in 35 and open cholecystectomy ( OC ) in 32 ) , were studied . - pubmed
In the LC group , 26 were classified as Child - Pugh class A , 8 as Child 's B class and 1 as Child 's class C. In the OC group , 12 were classified as Child 's class A , 15 as Child 's B and 5 as Child 's C. RESULTS : Complications occurred in 4 of 35 ( 12.3 % ) LC patients ( 1 patients was Child A and 3 were B ) . - pubmed
CONCLUSIONS : LC has a lower rate of complications than OC and is a reasonable option for Child 's class A and B patients with cirrhosis and gallstones . - pubmed
This finding provides insight into the etiology of cancer and the differences between genes involved in cancer and those implicated in other human diseases . - pubmed
Specifically , we found a significant overlap between human oncogenes and tumor suppressor genes and " essential genes , " human homologs of mouse lethal genes identified by knockout experiments . - pubmed
In the present paper , our aims were 1 ) to establish a new method to produce antihypertensive peptides ( AHP ) , and 2 ) to study the expression profiles of different host strains ( Escherichia coli JM109 and DH5alpha ) . - pubmed
Twenty hips of 19 patients with comminuted fractures or nonunion of the greater trochanter were stabilized with tension band technique . - pubmed
The patient has abductor weakness with Trendleburg limp but without pain . - pubmed
Six patients developed grade 1 heterotopic ossification and two patients grade 3 . - pubmed
None of the 19 patients experienced a dislocation during the follow - up . - pubmed
Of the three cows that reached the third trimester , one recipient died of hydrallantois 2 months before term , one aborted fetus was recovered at 8 months of gestation , and one delivered by cesarian section a healthy cloned calf . - pubmed
Interestingly , Todd was the first to present an electrical theory of epilepsy , supported by his own animal experimentation , well before his better - known successor John Hughlings Jackson ( 1835 - 1911 ) ( famous for his investigations of partial epilepsies and the eponymous " Jacksonian march " ) . - pubmed
Four patients from group P and none from group D reached an end - point of the study ( oliguria , renal dysfunction ) and received dopamine . - pubmed
Hepatitis B virus ( HBV ) is one of the major causes of liver disease worldwide . - pubmed
MATERIALS AND METHODS : Fifteen nodules of between 0.5 - 1.5 cm were localised in fifteen patients , of whom ten had antecedents of neoplasia , with the placement of spiral harpoon model Somatex , of 120 mm length and 18 G of Laboratorios Leleman , S.L. - pubmed
COPD patients Streptococcus pneumoniae vaccination give better pharmacoeconomic results in higher age - groups . - pubmed
Specific attention has been directed toward the beneficial effects afforded by dietary antioxidants , in particular those from fruit and vegetables , in ameliorating age - related deficits in brain performance . - pubmed
OBJECTIVES : To report one case of precocious puberty in a 6 - year - old boy with bilateral cryptorchidism . - pubmed
CONCLUSIONS : Genital ambiguity should be considered when evaluating a boy without palpable gonads . - pubmed
Diabetes was induced in New Zealand male rabbits with a single dose of alloxan ( 100 mg / kg , i.v . ) - pubmed
Silent cerebral infarction in patients with dilated cardiomyopathy : echocardiographic correlates . - pubmed
BACKGROUND : Patients with dilated cardiomyopathy ( DCM ) have an increased risk of thromboembolic events . - pubmed
Incidence of silent cerebral infarction ( SCI ) has not been investigated in these patients . - pubmed
The aim of this study was to investigate the incidence of SCI in patients with DCM and to determine its associations with echocardiographic parameters . - pubmed
METHODS AND RESULTS : Seventy - two patients ( mean age 62+/-12 years ) with DCM underwent cranial magnetic resonance imaging in addition to transthoracic and transesophageal echocardiographic examination . - pubmed
A total of 56 age - matched healthy volunteers served as a control group for comparison SCI prevalence . - pubmed
Prevalence of SCI was significantly higher in patients with DCM ( 35 % vs. 3.6 % ; p<0.001 ) . - pubmed
In DCM group , patients with SCI had significantly impaired left ventricular systolic function , higher frequency of restrictive diastolic filling , moderate to severe left atrial spontaneous echo contrast ( SEC ) , aortic SEC , and complex atherosclerosis or calcified plaques in the aorta . - pubmed
CONCLUSION : SCI is a frequent finding in DCM patients . - pubmed
Necrotic dermatitis in chickens . - pubmed
Common malignant musculoskeletal neoplasms of dogs and cats . - pubmed
Malignancies of the musculoskeletal system in dogs and cats can be categorized as either primary or metastatic within the bony or soft structures that comprise the musculoskeletal system . - pubmed
By far , the most common tumor that affects the musculoskeletal system in dogs is osteosarcoma . - pubmed
The most common tumors that affect the musculoskeletal system in cats are injection site sarcomas . - pubmed
These tumors are locally infiltrative ; whereas up to 25 % metastasize , most animals die from our inability to control local disease . - pubmed
Only by recognizing these patients as early as possible we will be able to reduce morbidity and mortality of this potentially dangerous syndrome . - pubmed
Administration of statins in combination with osteoporosis therapy appears to improve alveolar bone architecture in the mandibles of OVX rats with maxillary molar extraction . - pubmed
Statins continue to be considered as potential therapeutic agents for patients with osteoporosis and possibly with periodontal disease . - pubmed
Perceptuomotor functioning in preschool children with symptoms of attention deficit hyperactivity disorder . - pubmed
Given limited research on perceptual - motor functioning of preschool children with symptoms of ADHD , the purpose of this study was to compare the fine motor , gross motor , visuomotor , and oral - motor functioning of 49 4- to 6 - yr.-old children with symptoms of Attention Deficit Hyperactivity Disorder and 48 typically developing children . - pubmed
The method is verified with simulated data and demonstrated with experimental data from 2 studies , one clusters with respect to severity of disease in Alzheimer 's patients and another clusters data for a rat fracture healing study over time . - pubmed
These involves occupational risk factors as well as classic ones , such as obesity , limited physical activity or tobacco smoking . - pubmed
When OBP-401 was intratumorally injected into HT29 tumors orthotopically implanted into the rectum in BALB / c nu / nu mice , para - aortic lymph node metastasis could be visualized at laparotomy under a three - chip color cooled charged - coupled device camera . - pubmed
Ticks removed from 1136 dogs and 134 cats all over Japan were examined for Borrelia infection by PCR and sequencing . - pubmed
[ Electrode grids are available for the selection of patients with refractory epilepsy for epilepsy surgery ] . - pubmed
In 60 - 85 % of patients with refractory epilepsy , surgical excision of that part of the brain that is considered to be responsible for the development of epileptic seizures leads to the disappearance of the attacks . - pubmed
In the Netherlands , 60 - 70 patients undergo epilepsy surgery every year ; this is a small number in comparison to the number of potential candidates . - pubmed
Patients with medically refractory epilepsy without structural damage on the MRI or with a lesion in or near specialised areas of the cortex could also be examined and then treated surgically . - pubmed
Effect of atorvastatin withdrawal on circulating coenzyme Q10 concentration in patients with hypercholesterolemia . - pubmed
Coenzyme Q10 depletion has been speculated to play a potential role in statin - related adverse events , and withdrawal of statin is the choice in patients developing myotoxicity or liver toxicity . - pubmed
Twenty - six patients with hypercholesterolemia received atorvastatin at 10 mg / day for 3 months . - pubmed
METHODS : A 41 - year - old nulliparous woman presented with urinary incontinence following an abdominal hysterectomy , and office evaluation identified a vesicovaginal fistula . - pubmed
CONCLUSIONS : The robotic - assisted laparoscopic approach is a viable option for successful repair of a vesicovaginal fistula in a patient in whom a vaginal approach is not indicated . - pubmed
RESULTS : A 70 - year - old Japanese man was referred to the authors because of poorly controlled hypertensive keratouveitis in the left eye . - pubmed
The patient had a history of recurrent hypertensive anterior uveitis . - pubmed
The aqueous humor was investigated for herpes simplex virus , varicella - zoster virus and cytomegalovirus . - pubmed
Children scored 0.38 ( 95 % confidence interval 0.09 - 0.68 ) points higher on duration of orienting per SD decrease in total body weight gain from mid - pregnancy to birth . - pubmed
These results in mice suggest that stress exposure during adolescence may increase the risk for developing an alcohol - use and/or anxiety disorder in individuals with a genetic predisposition toward high alcohol consumption . - pubmed
Morphology of exertion - triggered plaque rupture in patients with acute coronary syndrome : an optical coherence tomography study . - pubmed
The aim of the present study was to use optical coherence tomography to investigate the relationship in patients with ACS between the morphology of a ruptured plaque and the patient 's activity at the onset of ACS . - pubmed
METHODS AND RESULTS : The study population was drawn from 43 consecutive ACS patients ( with or without ST - segment elevation ) who underwent optical coherence tomography and presented with a ruptured plaque at the culprit site . - pubmed
The purpose of our current study was to determine the effects of a novel combination of herbal extracts on intestinal inflammation using a murine model of IBD . - pubmed
Female Swiss - Webster mice were randomized to receive normal water or 5 % dextran sulfate sodium ( DSS ) drinking water to induce colitis . - pubmed
Motor and sensory assessment of patients in clinical trials for pharmacological therapy of acute spinal cord injury : psychometric properties of the ASIA Standards . - pubmed
The 2000 version of the ASIA Standards appear to be more reliable than the previous versions , although two prospective studies indicate that the ASIA Standards do not reliably assess children less than 4 years with SCI . - pubmed
PURPOSE : We evaluated clinicopathological features and outcomes in patients with penile squamous cell carcinoma . - pubmed
A 42 year - old woman develops steroid refractory graft - versus - host disease ( GVHD ) after second allogeneic stem cell transplantation for acute myelogenous leukemia with severe GVHD of her skin with blisters , severe GVHD of her gut with watery and bloody diarrhea and GVHD of her liver with cholestasis . - pubmed
We evaluated 70 melanomas from 70 patients seen at a single institution from 1997 to 2008 . - pubmed
METHOD : Twelve adults with persistent stuttering and 12 adults who had never stuttered each completed 4 ABA - format experiments . - pubmed
We report a case of acute carpal tunnel syndrome caused by periarticular calcification ( hydroxyapatite deposition disease ) around the wrist joint in a 64 - year - old woman . - pubmed
Obtaining normal tissue constraints using intensity modulated radiotherapy ( IMRT ) in patients with oral cavity , oropharyngeal , and laryngeal carcinoma . - pubmed
The mandibular constraints were met in 66 % , 29 % , and 57 % of patients with oral , oropharyngeal , and laryngeal cancers , respectively . - pubmed
Every experiment with the contents of one , or with those pooled from two to five of the normal stock of Rockefeller Institute strain of albino mice , 1 to 2 months of age , revealed the presence of a virus which , after intracerebral inoculation into normal mice , induced characteristic paralytic encephalomyelitis , indistinguishable from Theilerapos;s disease . - pubmed
No difference was seen in this effect of intestinal contents deriving from animals paralyzed during the course of spontaneous encephalomyelitis and from normal mice . - pubmed
The present , as well as previous work has shown that the virus found in normal ( or paralyzed ) mice is similar to that of Theiler ' s disease in all of its properties thus far investigated ; among the strains of the latter now at hand it can be classified with those having a low degree of invasiveness after peripheral inoculation . - pubmed
Our previous study showed that the high level of OTA contamination in wheat might be related to the high incidence of gastric carcinoma in rural area of China . - pubmed
In the present study , we explored the toxicity of OTA in human gastric epithelium immortalized cells ( GES-1 ) by analyzing the regulation of the cell cycle , apoptosis and its molecular mechanism . - pubmed
Further studies to explore the effectiveness of these methods and to motivate gachhis to invest their time and money to use them could reduce the risk of human Nipah infection in Bangladesh . - pubmed
It is a prototype of postinfectious autoimmune disease , whose pathophysiology is well described in the forms provoked by certain bacteria ( molecular mimicry with Campylobacter jejuni ) , but remains unclear for the forms related to other organisms ( cytomegalovirus , Epstein - Barr virus and other herpes group viruses , Mycoplasma pneumoniae ) . - pubmed
We report the observation of a 12 - year - old girl who presented with Guillain - Barre syndrome with facial diplegia , ataxia , and intracranial hypertension following Epstein - Barr virus ( EBV ) primary infection . - pubmed
EBV might be the factor that triggered the autoimmune disorders , as previously reported for systemic lupus erythematosus and multiple sclerosis in children . - pubmed
Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse . - pubmed
BACKGROUND : Several active ingredients proposed as vaginal microbicides have been shown paradoxically to increase susceptibility to infection in mouse genital herpes ( HSV-2 ) vaginal susceptibility models and in clinical trials . - pubmed
Twelve hours after exposure to the excipient or a control treatment , mice were challenged with a vaginal dose of HSV-2 , and three days later were assessed for infection by vaginal lavage culture to assess susceptibility . - pubmed
BACKGROUND / AIMS : The aim was to describe the factors determining total pubertal growth ( TPG ) in adolescents with growth hormone deficiency ( GHD ) , Turner syndrome ( TS ) , who were small for gestational age ( SGA ) or had idiopathic short stature ( ISS ) . - pubmed
One patient ( 4 % ) developed a retroperitoneal haematoma and required blood transfusion and one had haematuria that prolonged hospital stay by 2 days . - pubmed
Here we applied tensor - based morphometry to brain magnetic resonance imaging scans of 732 elderly individuals from the Alzheimer ' s Disease Neuroimaging Initiative study , to determine associations between homocysteine and brain atrophy . - pubmed
This association was also found when considering mild cognitive impairment individuals separately . - pubmed
METHODS : The effect of developing postoperative renal risk , injury or failure as defined by the RIFLE criteria on the long - term survival of patients undergoing isolated CABG with a normal renal function was studied . - pubmed
46.5 % of patients had chronic kidney disease ( CKD ) stage 1 ( GFR & gt;=90 ml / min/1.73 m(2 ) ) , 50.4 % had CKD stage 2 ( GFR 60 - 89 ml / min/1.73 m(2 ) ) and 3.1 % had CKD stage 3 ( GFR 30 - 59 ml / min/1.73 m(2 ) ) on admission , despite having a normal serum creatinine . - pubmed
In patients with normal preoperative serum creatinine , Cox regression analysis revealed that age ( P = 0.026 ) , preoperative creatinine ( P = 0.006 ) and logistic EuroSCORE ( P & lt ; 0.0001 ) were significant factors in addition to the development of postoperative renal risk , injury or failure ( P & lt ; 0.0001 ) , with regard to determining long - term survival . - pubmed
In patients with a preoperative GFR & gt;90 ml / min , Cox regression analysis revealed that diabetes ( P = 0.004 ) sex ( P = 0.019 ) and logistic EuroSCORE ( P & lt ; 0.0001 ) , were also significant factors in addition to the development of postoperative renal risk , injury or failure ( P = 0.0001 ) with regard to determining long - term survival . - pubmed
Second - generation antipsychotics ( SGAs ) are increasingly being used to treat children with a variety of psychiatric illnesses . - pubmed
The patient underwent a pterional craniotomy for surgical clipping of aneurysms associated with the AVM . - pubmed
Homeopathic treatment of migraine in children : results of a prospective , multicenter , observational study . - pubmed
OBJECTIVES : The study objective was to evaluate the effectiveness of homeopathic medicines for the prevention and treatment of migraine in children . - pubmed
SUBJECTS : Fifty - nine ( 59 ) physicians trained in the prescription of homeopathic medicines and 168 children , aged 5 - 15 years , with definite or probable migraine diagnosed using International Headache Society 2004 criteria were the subjects in this study . - pubmed
CONCLUSIONS : The results of this study demonstrate the interest of homeopathic medicines for the prevention and treatment of migraine attacks in children . - pubmed
Recent epidemiological studies have indicated that at least one in every 100 people has some form of ASD . - pubmed
Acute pancreatitis was induced in rats by clamping of inferior splenic artery for 30 min followed by reperfusion . - pubmed
Graded stenoses and total vessel occlusion of the carotid , aorta , and femoral arteries were created in 25 Wistar rats . - pubmed
Our perspective is that current studies on genes , environment , and immunity in this disease provides us with a great outlook to investigate interesting general aspects of autoimmunity and development of human autoimmune disease -- in addition to the opportunity to better understand , prevent , and ultimately treat RA . - pubmed
METHODS : One hundred and thirty - three patients with a poor PS ( Eastern Cooperative Oncology Group 3 or 4 ) were treated with palliative RT using the three - dimensional conformal technique and retrospectively analyzed . - pubmed
Grade 3 acute toxicity was observed in two patients ( 2 % ) and Grade 2 acute toxicity was observed in 10 patients ( 9 % ) . - pubmed
No Grade 2 or higher late toxicities were observed , except for Grade 3 radiation pneumonitis in one patient . - pubmed
The palliative effect is strongly correlated with prolongation of the survival time and may contribute to improving the remaining survival time in patients with metastatic / advanced cancer with a poor PS . - pubmed
Detection of DNA in hair could be , therefore , a useful tool to chronologically record the infection process during experimental mice assays . - pubmed
Adapalene 0.3 % for the treatment of acne in women . - pubmed
Design / objective : In this analysis , data from two studies comparing adapalene gel 0.3 % to vehicle gel were combined and evaluated for change in lesion counts and Investigator 's Global Assessment of success rates in adult female subjects ages 18 to 41 years with acne vulgaris . - pubmed
CONCLUSION : In this subgroup analysis , adapalene gel 0.3 % proved effective and well tolerated in adult women with acne vulgaris . - pubmed
OBJECTIVE : This study examined 1 ) the extent to which cocaine - dependent and non - addicted individuals differed on measures of intrinsic connectivity during fMRI Stroop performance ; and 2 ) the relationships between fMRI Stroop intrinsic connectivity and treatment outcome in cocaine dependence . - pubmed
CASE REPORT : A 54 - year - old woman was referred to us for cataract surgery in her left eye . - pubmed
Acute toxicity of multi - walled carbon nanotubes , sodium pentachlorophenate , and their complex on earthworm Eisenia fetida . - pubmed
The acute toxicities of MWCNTs and PCP - Na on earthworm Eisenia fetida were studied through different exposure methods ( filter paper contact test , immersion contact test , and artificial soil contact test ) . - pubmed
Our results indicated that the toxicity of PCP - Na on E. - pubmed
Transcranial direct current stimulation ( tDCS ) is a non - invasive neuromodulatory technique that can affect human pain perception . - pubmed
The present study investigated whether short - term tDCS reduced heat pain intensity , stress , blood pressure and increased heat pain thresholds in healthy volunteers when controlling for placebo effects . - pubmed
A total of 203 consecutive patients with acute PE were included . - pubmed
The RDW was higher in the CTEPH patients than the patients without CTEPH ( 17.04 + - 3.46 , 14.64 + - 1.82 , respectively , p = 0.015 ) . - pubmed
RDW was also higher in the CTEPH patients at the time of diagnosis of CTEPH during follow - up compared with the baseline RDW level at the time of PE diagnosis ( 18.63 + - 3.58 , 17.02 + - 3.59 , respectively , p = 0.014 ) . - pubmed
Although gray matter changes have been documented to be predictive of cognitive decline culminating in AD among healthy older adults , very little attention has been given to alterations in white matter as a possible MRI biomarker predictive of AD . - pubmed
In this investigation , we examined parahippocampal white matter ( PWM ) volume derived from baseline MRI scans in 2 independent samples of 65 cognitively normal older adults , followed longitudinally , to determine if it was predictive of AD risk . - pubmed
PURPOSE : To report the relative frequency of presenting signs in Tunisian children with retinoblastoma and to evaluate their prognostic impact . - pubmed
METHODS : A retrospective study was undertaken of 200 patients with retinoblastoma examined and treated between January 1993 and June 2009 . - pubmed
Nineteen children ( 9.5 % ) had a family history of retinoblastoma . - pubmed
In our series , 26 children ( 13 % ) presented with extraocular retinoblastoma . - pubmed
Human papillomavirus - related cell cycle markers can predict survival outcomes following a transoral lateral oropharyngectomy for tonsillar squamous cell carcinoma . - pubmed
OBJECTIVES : To identify the prognostic implications of human papillomavirus ( HPV)-related cell cycle marker profiles in patients who have received a transoral lateral oropharyngectomy ( TLO ) as a primary treatment for tonsillar squamous cell carcinoma ( TSCC ) . - pubmed
CONCLUSION : HPV - related cell cycle markers may also be good indicators for predicting survival after TLO for TSCC . - pubmed
Nine patients were excluded for known prostate cancer . - pubmed
Six ( 10 % ) patients were diagnosed with urinary tract infection . - pubmed
Qingyihuaji formula ( QYHJ ) , a traditional Chinese medicine , acts as an independent protective factor for pancreatic cancer patient survival and different patients have shown various responses to QYHJ treatment . - pubmed
Pituitary imaging findings in male patients with hypogonadotrophic hypogonadism . - pubmed
CONTEXT : Data on pituitary imaging in adult male patients presenting with hypogonadotrophic hypogonadism ( HH ) and no known pituitary disease are scarce . - pubmed
OBJECTIVE : To assess the usefulness of pituitary imaging in the evaluation of men presenting with HH after excluding known pituitary disorders and hyperprolactinemia . - pubmed
DESIGN : A historical prospective cohort of males with HH . - pubmed
Microadenoma was found in 8 ( 10.7 % ) , empty sella and thickened pituitary stalk in one patient ( 1.3 % ) each . - pubmed
Testicular tumors are very common among man under the age of 45 years . - pubmed
The recipient 's antibodies against the graft human leukocyte antigens are responsible for antibody mediated graft injury . - pubmed
Roughly half of the femoral fracture patients diagnosed with AFF according to the criteria suggested by a task force of the American Society for Bone and Mineral Research ( ASBMR ) have not undergone bisphosphonate ( BP ) therapy . - pubmed
We report a case of an 84 - year - old woman with AFF not treated by BP therapy , in whom underlying osteomalacia was histologically diagnosed . - pubmed
Patients with congeni - tal LLD treated with combined method of treatment had benefit from intramedullary alignment due to its better outcome . - pubmed
In vivo studies in Ehrlich ascites tumor bearing Swiss albino mice showed enhanced antitumor efficacy and minimal cardiotoxicity of polymersomes with ~90 % tumor regression as compared to ~38 % tumor regression observed with free doxorubicin . - pubmed
UNLABELLED : Toxoplasmosis is a zoonotic parasitic disease caused by protozoan , Toxoplasma gondii . - pubmed
Infections of human are common and are usually asymptomatic but it is so dangerous in immunosuppressed and HIV positive patients . - pubmed
RESEARCH DESIGN : Eighteen participants with TBI ( seven females ) and 19 healthy comparison participants ( CP ; eight females ) engaged in a 10 - minute conversation with an unfamiliar partner . - pubmed
METHODS : Resistance vessels from patients with ( n=12 ) and without ( n=13 ) chronic kidney disease were incubated in normal or high phosphate . - pubmed
In a high phosphate environment , endothelial and vascular dysfunction is evident in blood vessels and in man exposed to prolonged oral phosphate loading . - pubmed
Symptom - Based Treatment of Neuropathic Pain in Spinal Cord - Injured Patients : A Randomized Crossover Clinical Trial . - pubmed
OBJECTIVE : The objective of this study was to identify the differences in medication effect according to pain characteristics in spinal cord - injured patients . - pubmed
Fifty - five patients and 66 locations of neuropathic pain were included . - pubmed
Patients were divided into two groups : evoked pain present and evoked pain absent . - pubmed
RESULTS : Oxcarbazepine was significantly more effective for patients without evoked pain than in those with it for electrical , burning , and pricking pain . - pubmed
In patients with evoked pain , pregabalin was shown to be significantly more effective for electrical pain , allodynia , and heat hyperalgesia than oxcarbazepine . - pubmed
[ COMPARATIVE EFFECTIVENESS AND SAFETY OF NEW ORAL ANTICOAGULANTS AND WARFARIN IN PATIENTS WITH AGE - SPECIFIC NON - VALVULAR ATRIAL FIBRILLATION ] . - pubmed
The treatment of patients aged 65 - 74 and 75 - 80 yearsfor 2 years with dab itragan ( 110 mg b.i.d ) , apixaban ( 5 mg b. i. d ) , and rivaroxaban ( 20 mg once daily ) prevented stroke as effectively as warfarin therapy but less frequently caused severe intracranial hemorrhage . - pubmed
It is concluded that these new anticoagulants can be used as alternative medication for antithrombotic therapy of elderly patients with age - specific non - valvular atrialfibrillation . - pubmed
BACKGROUND : Patients with nonvalvular atrial fibrillation ( AF ) who undergo electrical cardioversion ( ECV ) tend to be younger and have less comorbidity . - pubmed
METHODS AND RESULTS : From January 2008 to June 2012 , 571 ECV were performed in 406 consecutive patients with nonvalvular AF . - pubmed
The purpose of this study was to evaluate this cortical and subcortical vascular hypointensity ( CSVH ) in patients with moyamoya disease . - pubmed
METHODS : Subjects were 20 consecutive patients with moyamoya disease . - pubmed
The numbers of CSVH in each hemisphere were counted and the numbers were compared between patients with moyamoya disease and controls . - pubmed
RESULTS : Patients with moyamoya disease had significantly more CSVH in the middle cerebral artery territory ( p & lt ; 0.001 ) and the anterior cerebral artery territory ( p & lt ; 0.001 ) compared with controls . - pubmed
The purpose of the present work was to study the cellular functions of endothelial and smooth muscle cells from the patients with aneurysms of the thoracic aorta . - pubmed
We studied endothelial and smooth muscle cells from aneurysms in patients with bicuspid aortic valve and with tricuspid aortic valve . - pubmed
To evaluate the potential contribution of miRNAs in acquired resistance to cisplatin in pancreatic cancer , we compared levels of more than 2000 human miRNAs in a cisplatin - resistant cell line ( BxPC3 - R ) derived from parental ( BxPC3 ) cells by step - wise exposure to increasing concentrations of the drug over more than 20 passages . - pubmed
Men with hypertension , recent fever , chemo or radiation exposure were excluded from the study . - pubmed
OBJECTIVES : This study evaluated the efficacy of ramelteon for insomnia in adult subjects with ADHD . - pubmed
CONCLUSIONS : Ramelteon is efficacious in maintaining an earlier sleep / wake cycle in adults with ADHD and CRSD but can have paradoxical fragmenting effects on sleep and exacerbate daytime sleepiness . - pubmed
Clinical Assessment of Urinary Tract Damage during Sustained - Release Estrogen Supplementation in Mice . - pubmed
The goal of this study was to develop a clinical scoring system and identify biomarkers of occult urinary tract lesions prior to the development of systemic illness in mice . - pubmed
All mice with urolithiasis had crystalluria , and 5 of the 6 mice with pyelonephritis or hydroureter had dilute urine ( that is , specific gravity less than 1.030 ) . - pubmed
A total clinical score of 3.5 ( maximum , 24 ) identified estradiol - supplemented mice with 83 % specificity and 50 % sensitivity , but no single clinical parameter , biomarker , or the total clinical score accurately predicted occult urinary tract lesions . - pubmed
To further characterize the pathogenic role of PCs , the expression levels of 17 selected miRs known to be involved in the development of CLL / SLL were compared in the PCs and the intervening small cell areas in lymph nodes of 15 patients with CLL / SLL . - pubmed
Combined administration of a sedative dose sevoflurane and 60 % oxygen reduces inflammatory responses to sepsis in animals and in human PMBCs . - pubmed
More than 50 allergens were associated with SCs including quaternium-15 ( 11.2 % ) , cocamidopropyl betaine ( 9.5 % ) , methylchloroisothiazolinone / methylisothiazolinone ( 8.4 % ) , coconut diethanolamide ( 7.9 % ) , fragrance mix I ( 7.7 % ) , Myroxylon pereirae ( 5.9 % ) , 4 - chloro-3,5 - xylenol ( 5.8 % ) , amidoamine ( 5.5 % ) , and formaldehyde ( 4.4 % ) . - pubmed
Methods : A hospital - based , cross - sectional study was carried out on 30 clinically diagnosed cases of infantile hemangioma and 30 controls presenting with other disorders . - pubmed
Streptococcus pyogenes is an exclusively human pathogen that can provoke mild skin and throat infections but can also cause fatal septicemia . - pubmed
Hand , Foot and Mouth Disease and Echovirus 3 : A Comment to Hogsberg & amp ; Bygum . - pubmed
One hundred three older individuals with varying cognitive impairment levels were included and underwent neuroimaging . - pubmed
They are taken up by human lung adenocarcinoma A549 cells very quickly and specifically target mitochondria . - pubmed
Seventy - two patients with head trauma were randomly allocated to equal intervention and control groups . - pubmed
Methodology : Sixty individuals were included in this study : OSCC ( 20 ) , PMD ( 20 ) and Control ( 20 ) . - pubmed
The present study investigated both autophagy and apoptosis in ICR mice and Human hepatocellular carcinoma cells ( HepG2 ) , and then explored the interactive mechanism between these two distinct cell death modalities in HepG2 cells . - pubmed
Mice liver injuries seen by hematoxylin and eosin ( HE ) staining indicated the hepatotoxic effects of nanosilica . - pubmed
To disambiguate the role of immunoglobulins in MI , we characterized the development of ischemic heart failure in agammaglobulinemic mice ( AID-/-muS-/- ) . - pubmed
These differences remained significant even after animals with matched infarct sizes were compared . - pubmed
METHOD : This retrospective study included 114 patients who underwent angiography for upper or lower GI bleeding . - pubmed
Patients with a history of malignancy were more likely to rebleed ( OR 4.4 , 95%CI 1.06 - 18.36 , p=0.04 ) . - pubmed
CONCLUSIONS : This paper identified important clinical predictors of arterial extravasation , rebleed and 30 - day mortality in GI bleedings , which will assist in patient selection and help to improve the overall angiographic management of GI bleeding . - pubmed
Results revealed that patients with mTBI had significantly reduced cortical thickness in the left entorhinal cortex while increased cortical thickness in the left precuneus cortex and right lateral occipital cortex , compared with healthy controls . - pubmed
Behavior problems in children with epilepsy and attention - deficit hyperactivity disorder in Central China . - pubmed
In this study , we aimed to evaluate the prevalence of attention - deficit hyperactivity disorder ( ADHD ) in children with epilepsy in Central China and compare the behavioral problems in children with epilepsy combined with and without ADHD . - pubmed
Children with epilepsy aged between 6 and 16 years were recruited for this study . - pubmed
Among 206 children diagnosed as having epilepsy , 51 had ADHD symptoms . - pubmed
Children with epilepsy and ADHD had significantly higher scores on attention problems , rule - breaking behavior , and aggressive behavior subscales ( P & lt ; 0.01 ) . - pubmed
Children with epilepsy and ADHD showed more behavior problems such as attention - deficit , delinquent , and aggressive behaviors compared with children with epilepsy only . - pubmed
Illicit drug use and acute kidney injury in patients admitted to hospital with rhabdomyolysis . - pubmed
Effect of Gmelina arborea on learning and memory in amnesia - induced and non - amnesia groups of albino Wistar rats . - pubmed
The crude extracts of the Gmelina arborea plant are reported to possess wound - healing , anti - diarrheal , anti - oxidant , anti - diabetic , and anti - ulcer property . - pubmed
arborea on learning and memory in albino Wistar rats . - pubmed
arborea on learning and memory in both amnesia - induced and non - amnesia groups of rats . - pubmed
Developmental delay , hypotonia , hypomyelination , and thyroid hormone profile help to diagnose patients . - pubmed
Maternal and neonatal outcomes following a diabetic pregnancy within the context of HIV . - pubmed
METHODS : Sample consisted of 40 normotensive men ( aged 31 - 59 years ) with no history of CVD of currently taking medication . - pubmed
Two patients developed cerebrovascular accidents . - pubmed
Spinal cord injury occurred in 2 patients . - pubmed
Postoperative renal failure , postoperative extracorporeal membrane oxygenation support , and pneumonia were reported in 3 , 1 , and 6 patients , respectively . - pubmed
Stent - related aortic complications were observed in 5 patients ( 6.8 % ) . - pubmed
The 17 - year old patient suffers from multiorgan failure . - pubmed
Targeted tumour theranostics in mice via carbon quantum dots structurally mimicking large amino acids . - pubmed
Effects of nebivolol versus other antihypertensive drugs on the endothelial dysfunction in patients with essential hypertension . - pubmed
Patients with ventricular assist devices ( VADs ) and extracorporeal membrane oxygenation ( ECMO ) suffer from an increased risk for thromboembolic events as well as for hemorrhages . - pubmed
xSafety , Tolerability , and Pharmacokinetics of Crenezumab in Patients with Mild - To - Moderate Alzheimer ' s Disease Treated with Escalating Doses for up to 133 Weeks . - pubmed
METHODS : In this multicenter , double - blind study , participants ( aged 50 - 90 years ) with mild - to - moderate Alzheimer ' s disease ( AD ) and amyloid - positive PET scan were randomized to receive crenezumab 30 or 45 mg / kg ( Cohort 1 , n = 21 ) , 60 mg / kg ( Cohort 2 , n = 21 ) , or 120 mg / kg ( Cohort 3 , n = 19 ) or corresponding placebo ( n = 14 ) intravenously q4wfor 13 weeks . - pubmed
Since its introduction to North America in the early 1900s , white pine blister rust ( WPBR ) caused by the fungal pathogen Cronartium ribicola has resulted in substantial economic losses and ecological damage to native North American five - needle pine species . - pubmed
Open - pollinated seed families were evaluated for host reaction following controlled infection using C. - pubmed
To the best of our knowledge , this is the first verification of AS in EEG signals and in the human brain . - pubmed
Based on this , we present a new in vitro culture protocol to obtain polyploid organisms using zeatin riboside ( ZR ) and eggplant as a model organism . - pubmed
The regeneration of whole plants from the appropriate tissues using ZR allowed developing polyploid individuals in eggplant , a crop that tends to be recalcitrant to in vitro organogenesis . - pubmed
It has been linked to the risk of development of spondyloarthritis , and it associates with the immune infiltration of tumours and strongly predicts the overall survival for patients receiving check - point inhibitor therapy . - pubmed
The pooled prevalence of Plasmodium falciparum and Plasmodium vivax , and mixed infections were 12 , 30 , and 6 % , respectively . - pubmed
BACKGROUND : The durability of improved xerostomia with intensity - modulated radiotherapy ( IMRT ) in patients with early stage nasopharyngeal carcinoma ( NPC ) is uncertain . - pubmed
METHODS : Parent study participants ( IMRT , n = 28 ; 2DRT , n = 28 ) who were free of second malignancy or recurrence were eligible . - pubmed
Long - term patient - reported outcomes were assessed by the six - item xerostomia ( XQ ) and two European Organisation for Research and Treatment of Cancer ( EORTC ) questionnaires ( QLQ - C30 , QLQ - H&N35 ) . - pubmed
Patients in the IMRT arm reported lower mean scores for the " dry mouth " domain of EORTC QLQ - H&N35 ( p = 0.02 ) and showed trends toward better 15 - year OS ( 81.5 % vs. 53.8 % , p = 0.06 ) , LRFS ( 70.6 % vs. 53.8 % , p = 0.38 ) , and DRFS ( 81.5 % vs. 53.8 % , p = 0.07 ) . - pubmed
CONCLUSIONS : The parotid - sparing effect of IMRT in NPC treatment is durable , with significantly less physician- and patient - scored xerostomia at 15 years . - pubmed
CONCLUSIONS : Since its clinical presentation is variable , clinical suspicion is important in the presence of a skin lesion of torpid evolution taking into account the patient 's oncological history . - pubmed
Recent developments in bovine leukemia research and regulatory programs . - pubmed
[ Development of strains of molossinus mice and their application -- significance of their species characteristics ] . - pubmed
28 patients with spondylolisthesis who underwent anterior interbody fusion at the Orthopaedic Department of the University of Basle between 1968 and 1976 , have been follow - up . - pubmed
A patient with a large , long - standing posterior fossa arachnoid cyst was evaluated . - pubmed
Studies on the susceptibility of the laboratory animals , kids , and lambs to experimental infection with Schistosoma nasale Rao 1933 . - pubmed
Intravenous miconazole monotherapy for 3 weeks cured a 67 - year - old patient with a 2 - year history of esophageal candidiasis . - pubmed
Some circulatory and respiratory effects of morphine in patients without pre - existing cardiac disease . - pubmed
morphine ( 10 mg/70 kg body weight ) were studied in 10 adults with unimpaired circulatory function . - pubmed
Cell - mediated antitumor immunity in breast cancer patients evaluated by antigen - induced leukocyte adherence inhibition in test tubes . - pubmed
Tumor antigen - induced inhibition of leukocyte adherence was adapted and modified for use in glass test tubes for the study of cell - mediated antitumor immunity to human adenocarcinoma of the breast . - pubmed
Peripheral blood leukocytes from 40 to 47 patients with proven breast cancer responded to an antigenic extract of breast cancer with significant leukocyte adherence inhibition , whereas only 2 of 32 controls showed a response . - pubmed
Further , 7 patients with histologically proven benign breast disease did not react to the breast adenocarcinoma extract , indicating that only breast cancer patients have leukocytes sensitized to the breast cancer antigen . - pubmed
The cell - mediated antitumor response of the breast cancer patient was dependent on the stage of the cancer , and patients with disseminated cancer had decreased responsiveness . - pubmed
In P(A ) H block group ( 23 cases ) , the permanent pacemaker implantation was not needed except for one patient with persistent heart failure due to marked bradycardia . - pubmed
BACKGROUND AND METHODS : We performed a multicenter , randomized , unblinded clinical trial ( the Foscarnet - Ganciclovir Cytomegalovirus Retinitis Trial ) designed to compare ganciclovir with foscarnet in the treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome ( AIDS ) . - pubmed
The patients were followed for the progression of retinitis , visual loss , and death . - pubmed
CONCLUSIONS : These results suggest that for patients with AIDS , and cytomegalovirus retinitis , treatment with foscarnet offers a survival advantage over treatment with ganciclovir , although the patients may not tolerate foscarnet as well as ganciclovir . - pubmed
Deletion of chromosome 11p13 - 11p15.5 sequences in invasive human ovarian cancer is a subclonal progression factor . - pubmed
In human ovarian cancer , multiple specific chromosomal deletions can be found by cytogenetic analysis or molecular techniques such as restriction fragment length polymorphism probing . - pubmed
Expression of a transfected H-2Kb gene in B16 cells correlates with suppression of liver metastases in triple immunodeficient mice . - pubmed
injected B16 - F1 and B16 - F10 murine melanoma cells to colonize not only the lungs but also the liver of TD mice . - pubmed
Bacterial skin infection with Staphylococcus aureus and sometimes beta - haemolytic streptococci is common and is best treated with oral antibiotics . - pubmed
A multimodality approach of moderate - dose to high - dose preoperative radiation therapy , surgical resection , and intraoperative electron beam radiation therapy ( IORT ) has been used for patients with locally recurrent rectal or rectosigmoid carcinoma . - pubmed
The 5 - year actuarial local control and disease - free survival for 30 patients undergoing this treatment program were 26 % and 19 % , respectively . - pubmed
The determinant local control and disease - free survival for 13 patients undergoing complete resection were 62 % and 54 % , respectively , whereas for 17 patients undergoing partial resection these figures were 18 % and 6 % , respectively . - pubmed
For the 30 patients undergoing external beam irradiation , resection , and IORT , the most significant toxicities were soft tissue or sacral injury and pelvic neuropathy . - pubmed
Rhodococcus equi is an uncommon pathogen in humans that has occasionally been reported to cause infection in individuals with impaired cellular immunity . - pubmed
We summarize 30 previously published reports of human infection with R. equi and describe one additional case in a patient with AIDS . - pubmed
Seventy - seven percent of all patients had pneumonia due to R. - pubmed
When HIV - infected patients were compared with those not infected with the virus , symptoms , age , and frequency of pneumonia were similar . - pubmed
Individuals with HIV infection also had a higher incidence of simultaneous secondary infections and higher mortality than non - HIV - infected patients ( 54.5 % vs. 20 % ) . - pubmed
[ Effectiveness of therapeutic and preventive procedures in children with chronic digestive system diseases in a day - care hospital ] . - pubmed
The author characterizes in detail 4340 patients with diffuse renal lesions ( chronic glomerulonephritis , renal amyloidosis , lupoid nephritis , diabetic glomerulosclerosis and nephrosclerosis ) coupled with different diseases of the urinary organs including urolithiasis , cancerous and tuberculous processes , purulent diseases of the kidneys and prostatic lesions . - pubmed
Stage III chronic renal failure ( CRF ) was revealed in 2073 ( 57.1 % ) out of the 4340 patients . - pubmed
The shortest times of CRF onset , the highest frequency of stage III CRF and the least lifespan were noted in patients with double association , particularly in those suffering from associated chronic glomerulonephritis with renal amyloidosis and urinary bladder cancer in the stage of compression with tumor of the intramural parts of the ureters , namely they were 0.6 + /- 0.1 , 100 % and 1.0 + /- 0.1 yr . - pubmed
The author holds that the main reason for such an abrupt CRF onset in patients with concomitant renal lesions of any type lies in simultaneous combined influence on the kidneys of absolutely different diseases bearing in mind their etiology and pathogenesis . - pubmed
We examined ozone - induced airway inflammatory responses in inbred mice , and progeny of crosses between them , to investigate genetic susceptibility to ozone . - pubmed
Two patients with resectable secondaries in the liver developed needle track recurrence following intraoperative " Trucut"-needle biopsy and percutaneous thin needle aspiration cytology , respectively . - pubmed
Patients with stable chronic renal failure maintained on protein restriction were given sodium bicarbonate supplementation for 8 weeks . - pubmed
Some opisthorchiasis foci are found in the Biryusa basin , local cases of human invasion are registered in regions on the Taseyeva river , down the Angara , and in one of the Yenisei regions where invasion foci of low intensity are supposed to exist . - pubmed
Social and cultural habits of human populations affect the biological evolution of the agents of infectious diseases . - pubmed
Burn patients often exhibit prolonged cell - mediated immune suppression . - pubmed
Triplicate samples of 10 % dilutions of burn serum from nine burn patients ( three with greater than 60 % burn ) were analyzed for their ability to suppress mitogen - induced lymphocyte blastogenesis . - pubmed
The serum of patients with greater than 60 % burn was significantly more suppressive ( as measured by depressed tritiated thymidine incorporation by cultured lymphocytes ) than that taken from patients with smaller burns . - pubmed
Altered function of synovial fluid granulocytes in patients with acute inflammatory arthritis : evidence for activation of neutrophils and its mediation by a factor present in synovial fluid . - pubmed
Survival of the islet grafts was also independent of the duration of diabetes in the BB / W rats at the time of transplantation . - pubmed
Similar changes occur during normal development , but the ( n-3 ) to ( n-6 ) ratio of PUFA in these phosphoglycerides of Down ' s syndrome at the fifth month of gestation resembled that of normal human cerebral grey matter at term . - pubmed
Comparison of effects of three anesthetic agents on induction of ventricular tachycardia in a canine model of myocardial infarction . - pubmed
The effects of three anesthetic agents on the inducibility of ventricular tachycardia by programmed stimulation were investigated in dogs with a surgically induced left ventricular infarct . - pubmed
Endocardial catheter electrodes were placed at the right ventricular apex under general anesthesia at least 2 weeks after infarction , and the dogs were allowed to recover for 24 hours before undergoing programmed stimulation in the conscious state on two occasions 2 hours apart . - pubmed
In 15 animals , ventricular tachycardia was inducible on both occasions with 3.4 + /- 0.4 ( mean + /- SEM ; range , 1 - 5 ) extrastimuli . - pubmed
The ability to induce ventricular tachycardia was abolished in five of 10 animals ( p less than 0.05 ) . - pubmed
In the animals that remained inducible , the cycle length of tachycardia increased from 153 + /- 10 to 168 + /- 10 msec ( p = 0.015 ) , while the number of extrastimuli required was unaltered . - pubmed
Ventricular tachycardia remained inducible in only six of 10 dogs ( p less than 0.05 ) with no change in cycle length or the number of extrastimuli required . - pubmed
Ventricular fibrillation was inducible in an additional three dogs with a number of extrastimuli similar to that required to induce ventricular tachycardia before anesthesia. - pubmed
Testing ciliary activity in patients with chronic and recurrent infections of the upper airways : experiences in 68 cases . - pubmed
Therefore , biopsy specimens of the nasal mucosa were investigated by means of phase contrast microscopy in 68 patients with chronic and recurrent infections of the upper airways . - pubmed
Ultrastructurally , a characteristic pattern of defective dynein arms as observed in primary ciliary dyskinesia , was evident in only 3 out of these 19 patients . - pubmed
Over a 9 - month period 228 men were admitted for acute urinary retention to six different casualty wards in the Copenhagen area . - pubmed
The etiology of the acute retention was infravesical obstruction in 90 % of the patients , and 85 % required subsequent surgical treatment . - pubmed
In several previous rodent studies , the toxicity and tissue concentrations of iodipamide ethyl ester ( IDE ) particles have been evaluated . - pubmed
SP recorded from the genital skin is a useful method of evaluating the autonomic - sympathetic dysfunction causing impotence , especially in patients who may have autonomic disorders either located in lumbosacral spinal cord and its efferents , or generalized autonomic - peripheral dysfunction . - pubmed
A comparative study of peritoneal fluid concentrations of oestradiol-17 beta , progesterone , and testosterone in controls and in patients with endometriosis . - pubmed
Forty six patients ( mean age , 30.1 + /- 6 years ) with pelvic endometriosis and 32 control patients ( mean age , 32.2 + 3.8 years ) without endometriosis were studied . - pubmed
The new long - acting ergoline derivative cabergoline was given orally in a single dose of 300 micrograms to 15 hyperprolactinemic patients ( including 4 acromegalic patients , 2 of whom were dopamine responsive ) . - pubmed
The only symptomatic side - effect was orthostatic hypotension after cabergoline in an elderly woman . - pubmed
These data indicate that cabergoline has potent and prolonged dopaminergic activity and may prove suitable for once weekly treatment of hyperprolactinemic patients . - pubmed
The incidence of acute and chronic liver damage and its relation to hepatitis B virus ( HBV ) infection was evaluated in 164 consecutive children with acute leukemia seen in ten Italian hemato - pediatric units . - pubmed
Thirteen out of 164 children ( 7.9 % ) had acute hepatitis ( AH ) during treatment , while 8/90 ( 8.8 % ) showed an acute exacerbation of liver damage within 6 months after therapy withdrawal . - pubmed
Seven of the 13 children with AH while on therapy were HBsAg positive . - pubmed
Five of eight children who developed AH after completion of treatment were HBsAg positive . - pubmed
The outcome of these liver diseases after treatment withdrawal did not differ significantly in relation to HBV serology , suggesting that viral rather than toxic agents were responsible for liver damage also in most HBsAg - negative patients . - pubmed
The high incidence of chronic HBV infection in children with leukemia found in this multicentric study could suggest a need for active immunization with HBV vaccine , but the efficacy of such approach in this clinical setting is still to be validated . - pubmed
Sonography as a substitute for excretory urography in children with urinary tract infection . - pubmed
The possibility was explored of substituting renal sonography for excretory urography in children with urinary tract infection . - pubmed
A comparative study on the effects of ascorbic acid deficiency and supplementation on endurance and mitochondrial oxidative capacities in various tissues of the guinea pig . - pubmed
The aim of this study was to ascertain the effects of ascorbic acid deficiency and supplementation on endurance and mitochondrial oxidative capacities in various tissues of guinea pigs . - pubmed
Experience with the management of 106 consecutive patients found to have a retroperitoneal haematoma ( RH ) at laparotomy for penetrating trauma over a 2 - year period is reviewed . - pubmed
Fourteen patients died ( 63.8 per cent ) representing 70 per cent of all deaths in the series . - pubmed
Type III RH was found in 11 patients and was due to iliac vessel injuries . - pubmed
Pineal denervation by cervical sympathetic ganglionectomy suppresses the role of photoperiod on pregnancy or pseudopregnancy , body weight and moulting periods in the mink ( Mustela vison ) . - pubmed
Fifty - four patients with advanced upper gastrointestinal cancer were assessed for their nutritional status prior to any form of therapy . - pubmed
Identity of a newly isolated human polyomavirus from a patient with progressive multifocal leucoencephalopathy . - pubmed
Isolation of a strain of polyomavirus , designated COL , from the brain of a patient with progressive multifocal leucoencephalopathy is described . - pubmed
The COL strain is antigenically similar to JC polyomavirus , previously isolated from a brain affected by progressive multifocal leucoencephalopathy and is unrelated to BK , another human polyomavirus isolated from urine . - pubmed
Some effects of protein deficiency in young growing pigs . - pubmed
Aggregation of washed platelets from stroke - prone spontaneously hypertensive rats(SHRSP ) was markedly reduced with the development of hypertension in comparison with age - matched normotensive Wistar Kyoto rats(WKY ) ( Tomita et al . - pubmed
The experience with 43 consecutive chest wall resections in patients with breast cancer affords the opportunity to define indications and contraindications for such palliative procedures . - pubmed
Three patients who underwent resection for local recurrence have survived 40 months or more free from disease . - pubmed
In the proper setting , chest wall resection is an important part of the armamentarium for palliation of the patient with breast cancer . - pubmed
Both synthetic and natural estrogens have been studied for their ability to induce renal carcinomas in castrated male hamsters after 9.0 months of treatment . - pubmed
tumor foci ] in these animals . - pubmed
However , alpha - dienestrol and DES 3,4 - oxide showed an 86 to 88 % incidence of renal tumors in hamsters ( approximately 10.8 + /- 3 ) . - pubmed
Moreover , the poor carcinogenic activity of ethinyl estradiol in this system , despite strong estrogenicity , suggests that estronic activity alone may not be sufficient to effect renal tumorigenesis in the hamster . - pubmed
Treatment of a 60 - year - old woman with scleromyxoedema with 8 - methoxypsoralen and UV - A radiation ( PUVA ) resulted in significant clinical and histological improvement but no change in circulating paraprotein . - pubmed
In a prospective study of 336 consecutive patients with long - term pleural effusions , 32 cases of malignant mesothelioma were found . - pubmed
The effect of sublingual or intracoronary nitroglycerin ( NTG ) on luminal caliber in normal and diseased portions of epicardial coronary arteries was determined in 85 lesions from 57 typical patients with ischemic heart disease . - pubmed
Edematous necrosis in thiamine - deficient encephalopathy of the mouse . - pubmed
Acute encephalopathy was produced in the adult male Swiss mouse by pyrithiamine injection in conjunction with a thiamine - deficient diet . - pubmed
These lesions of thiamine - treated encephalopathy of the mouse closely resembled the non - hemorrhagic lesions of human Wernicke encephalopathy . - pubmed
Mice which were concomitantly - induced with hyperglycemia and encephalopathy showed no significant differences in clinical and morphologic manifestations from the encephalopathic mice with normal blood sugar levels . - pubmed
The patients who survive gallbladder carcinomas more than five years are usually those in whom the carcinoma was first diagnosed at microscopic examination of gallbladders removed for presumed benign disease . - pubmed
The prognosis was far better in the 11 patients in which the cancer was confined to the mucosa or submucosa . - pubmed
Five of the 11 patients died because of recurrence . - pubmed
Radical cholecystectomy including a wedge resection of liver tissue and dissection of the regional lymph nodes is recommended in all patients with inapparent gallbladder carcinomas . - pubmed
Signs of kidney dysfunction detectable in urinary protein excretion were searched for in a group of 86 silica - exposed workers who were compared to 86 control subjects matched for age , smoking status and body mass index . - pubmed
Only a few people know that the native Swiss and student of Pasteur and Roux spent nearly 50 years of his life in Vietnam , where he became director of the Pasteur institutes and earned merits by his engagement for the control of communicable diseases in humans and animals . - pubmed
Ondansetron reduces the incidence and severity of poststrabismus repair vomiting in children . - pubmed
The number of children vomiting prior to discharge and within 24 h of surgery was significantly reduced in Group 3 compared with Group 1 ( P & lt ; 0.003 and P & lt ; 0.015 , respectively ) . - pubmed
The number of vomiting episodes per patient in Groups 1 , 2 , and 3 was 1.1 , 0.5 , and 0.1 prior to discharge , and 4.5 , 2.6 , and 1.2 during the 24 h after surgery ( P & lt ; 0.0005 and P & lt ; 0.004 , respectively ) . - pubmed
OBJECTIVE : This study was done ( 1 ) to determine whether congenital indirect inguinal hernias in male pigs could be repaired by placing a polypropylene mesh prosthesis over the defect intra - abdominally , ( 2 ) to measure the incidence of adhesions between intra - abdominal viscera and the prosthesis with and without the adhesion barrier oxidized regenerated cellulose , ( 3 ) to determine the incidence of other complications , and ( 4 ) to assess the effect on fertility . - pubmed
METHODS : In male pigs , polypropylene mesh alone or polypropylene mesh plus the adhesion barrier oxidized regenerated cellulose ( composite prosthesis ) was fixed to the peritoneum surrounding the hernia defect . - pubmed
Human gene therapy is one of the promising approaches in treatment of genetic diseases and rapid development of molecular genetic methods is bringing this therapy in life . - pubmed
Metabolism of antipyrine in vivo in two rat models of liver cirrhosis . - pubmed
We investigated to what extent antipyrine clearance and metabolite formation are impaired in two models of liver cirrhosis in the rat , namely micronodular cirrhosis induced by chronic exposure to phenobarbital / CCl4 and biliary cirrhosis induced by bile duct ligation . - pubmed
The microsomal cholesterol content was increased by 16 % and 90 % in CCl4 and bile duct - ligated cirrhotic rats ( P & lt ; 0.001 ) , respectively . - pubmed
Unilateral renal artery revascularization can salvage renal function and terminate dialysis in selected patients with uremia . - pubmed
Revascularization of renal arteries to salvage glomerular function in patients with chronic renal failure is performed infrequently . - pubmed
However , during the past 12 months we have encountered three patients over 60 years of age known to have chronic renal failure who were on dialysis for 2 weeks , 3 weeks , and 2 months , respectively . - pubmed
All three patients were hypertensive , requiring between four and five antihypertensive medications . - pubmed
One patient was ventilator dependent in intractable cardiac failure with pulmonary artery systolic pressures ranging from 60 to 70 mm Hg . - pubmed
Standard biplanar arteriography revealed occlusion of the left renal artery with distal reconstitution in two patients and a 99 % stenosis of the right renal artery in the remaining patient . - pubmed
[ Immediate effect of hemodialysis with cuprophane membrane and acetate containing dialysis fluid on respiratory function in patients with chronic renal failure ] . - pubmed
In 20 patients with chronic renal failure on a hemodialysis ( HD ) programme with a cuprophane membrane and acetate - containing dialysis fluid , gasometric parameters , ventilation disturbances and peripheral blood leucocyte count were determined . - pubmed
We report here on a female Greek patient with homozygous beta - thalassemia but normal growth and development , excellent exercise tolerance , and no need of blood transfusions . - pubmed
34 patients with metastatic colorectal cancer were treated with the ether lipid miltefosine ( hexadecylphosphocholine ) . - pubmed
Nausea and vomiting were the most frequent side - effects occurring in all but 3 patients , nephrotoxicity was observed in 11 patients . - pubmed
Leucocytosis was observed in 24 and thrombocytosis in 17 patients . - pubmed
1 patient obtained a partial response of liver metastases for a duration of 8 months . - pubmed
Three patients with histologically confirmed ascarid granuloma who presented clinically with abdominal masses simulating abdominal tuberculosis or lymphoma are described . - pubmed
Since NaHCO3 is a treatment option in patients with severe metabolic acidosis , the purpose of this study was to examine the acute effect of the administration of NaHCO3 on back - titration of non - bicarbonate buffers in metabolic acidosis . - pubmed
In group A , 22 patients ( 24.2 % ) resulted as suffering from prostatic carcinoma , 4 ( 4.3 % ) resulted as suffering from prostatic phlogosis , and 65 ( 71.4 % ) resulted as suffering from BPH . - pubmed
The rats were water loaded with 5 % of their body weight by gavage twice , with the second gavage one hour after the first . - pubmed
In this study we have evaluated the fluence rate effect with a second - generation photosensitizer , tetra ( m - hydroxyphenyl ) chlorin ( mTHPC ) using a 7,12 - dimethylbenz ( a ) anthracene induced early squamous cell carcinoma of the Syrian hamster cheek pouch as a tumor model . - pubmed
PURPOSE : Patients with aneurysmal disease involving both the descending thoracic and abdominal aorta have historically required simultaneous or sequential conventional operations , but the morbidity rate is high with either approach in these patients , who often exhibit coexisting cardiopulmonary disease . - pubmed
Transluminally placed endovascular grafts have recently been developed for repair of aortic aneurysms , and we have implemented these techniques to eliminate the need for a thoracotomy in patients with multilevel aortic disease . - pubmed
No patients required further surgical intervention to treat their aortic disease . - pubmed
Seventeen patients ( 94 % ) are currently well 14 + /- 8 months after surgery ( range , 3 to 29 months ) with completely excluded thoracic aortic disease , no stent migration , and no change in stent configuration documented by serial radiologic examinations . - pubmed
CONCLUSIONS : Simultaneous abdominal aortic replacement and deployment of a thoracic stent - graft can safely exclude multilevel aortic aneurysmal disease and may be a valuable treatment option for these otherwise high - risk patients . - pubmed
We now study the correlation between the plasma antioxidant capacity and tissue oxidative damage , after acute ( one and two doses ) and prolonged ( eight doses ) ALA treatment of rats ( one dose of ALA = 40 mg / kg body weight ) . - pubmed
Expression of a pim-2 transgene in lymphoid cells predisposed mice to T - cell lymphomas like those promoted by pim-1 transgenes . - pubmed
Moreover , strong collaboration with an E mu - myc transgene was manifested as pre - B cell leukemia in neonate bi - transgenic animals . - pubmed
These methods were used to ascertain the L - DOPA / L - tyrosine ratio in plasma of patients with melanoma . - pubmed
For 29 patients diagnosed as having melanoma without metastasis , the L - DOPA / L - tyrosine ( 11.96 x 10(-5 ) + /- 2.69 x 10(-5 ) ) level was not significantly different from that of 35 normal controls ( 11.20 x 10(-5 ) + /- 2.92 x 10(-5 ) ) . - pubmed
However , this level was significantly increased ( p & lt ; 0.05 ) in the plasma of 17 patients with developing metastasis ( 21.02 x 10(-5 ) + /- 4.68 x 10(-5 ) ) . - pubmed
A hypertensive crisis was induced by metoclopramide , a widely used anti - emetic , in a pregnant normotensive woman . - pubmed
Lameness in the dairy cow : pain and welfare . - pubmed
The fatty acid profile of subcutaneous fat and blood plasma in pruritic dogs and dogs without skin problems . - pubmed
Group 2 was comprised of dogs with pruritus and compatible clinical signs of atopy . - pubmed
In subcutaneous fat , the concentration of adrenic acid ( 22:4n-6 ) was lower in the group of pruritic dogs compared to dogs with healthy skin . - pubmed
The amount of dihomogammalinolenic acid ( 20:3n-6 ; DGLA ) in plasma lipids from pruritic dogs was higher than in dogs without skin problems . - pubmed
Methods of identifying patients at high risk of subsequent arrhythmic death after myocardial infarction . - pubmed
Cerebral magnetic resonance imaging in patients with chronic liver disease . - pubmed
Future studies employing magnetic resonance imaging techniques to obtain information on cerebral function or combined with magnetic resonance spectroscopy to obtain localized biochemical information might further our understanding of the pathogenesis of hepatic encephalopathy in cirrhotic patients . - pubmed
OBJECTIVE : To enhance awareness of issues affecting patients with chronic renal failure and to provide guidance for primary care practitioners managing such patients . - pubmed
The benefits of lipid lowering are suggested by randomized trials among patients without renal disease . - pubmed
MAIN MESSAGE : Progression of renal failure , particularly in patients with proteinuria , can be slowed by lowering blood pressure . - pubmed
CONCLUSIONS : Care of patients with progressive renal failure is complex and requires attention to detail . - pubmed
OBJECTIVES : Patients with Parkinson ' s disease characteristically have difficulty in sustaining repetitive motor actions . - pubmed
METHODS : Ocular pursuit in seven patients with moderate to severe bradykinesia predominant Parkinson ' s disease was compared with seven age matched controls . - pubmed
The distinctive findings in patients with Parkinson ' s disease were a reduction in response magnitude compared with controls and a progressive decline of response with stimulus repetition . - pubmed
The clinical significance of hepatitis G virus ( HGV ) infection was studied in 35 patients with various liver diseases of unknown etiology . - pubmed
HGV RNA was detected in 3 of 5 cases of acute hepatitis , 3 of 23 cases of chronic liver diseases , and 1 of 7 cases of hepatocellular carcinoma . - pubmed
The HGV positive rate was high in patients with acute hepatitis suggesting that HGV might cause acute liver injury . - pubmed
Therefore , HGV was thought to be an important etiological agent for liver injury . - pubmed
Acute GVHD of grades II - IV developed in six patients transplanted with PBPC and three patients transplanted with BM . - pubmed
The numbers of patients with chronic GVHD were 15 and 8 , respectively . - pubmed
A fatal case of methane and cyanide poisoning among a group of deep sea trawler men is described . - pubmed
We have demonstrated previously that the preferential adhesion of prostate cancer cells to human bone marrow endothelial ( HBME ) cells may contribute to their preferential metastasis to bone . - pubmed
Two aerobic bacterial strains , a chlorophenol - degrading bacterium characterized in this work as a Ralstonia sp . - pubmed
Preoperative risk assessment for gastrostomy tube placement in head and neck cancer patients . - pubmed
METHODS : We performed a retrospective chart review of 142 patients who underwent extirpative surgery for head and neck cancer . - pubmed
Candida albicans , as an opportunistic pathogen , causes therapeutic problems in immunocompetent individuals and frequently it initiates severe infections in immunocompromised hosts . - pubmed
albicans infections in inbred ICR mice which have normal complement production . - pubmed
infections in DBA/2 mice which are deficient in C5 complement component . - pubmed
The preparation enhanced delayed type hypersensitivity to the yeast cells in both mouse strains . - pubmed
albicans infection in ICR mice treated with cobra venom and cyclophosphamide . - pubmed
All patients received standard anti - microbials and graft - versus host disease ( GVHD ) prophylaxis including cyclosporin A and a short course of methotrexate . - pubmed
Early portal vein thrombosis is a rare but severe posttransplant complication that may lead to graft and/or patient loss . - pubmed
PATIENTS : The study was based on patients treated for skeletal metastases , myeloma or lymphoma between 1986 and 1998 at the Oncology Service , Department of Orthopedics , Karolinska Hospital and on patients diagnosed with symptomatic skeletal metastases 1989 - 1994 in the Stockholm Region . - pubmed
EPIDEMIOLOGY : 641 breast cancer patients were diagnosed with symptomatic skeletal metastases 1989 - 1994 . - pubmed
Multivariate analysis based on 619 patients showed that complete pathologic fracture and soft tissue metastases were negative prognostic variables for 1 - year survival after operation . - pubmed
DIAGNOSIS : Fine Needle Aspiration Biopsy ( FNAB ) was assessed in 110 patients for diagnostic accuracy and to which extent information about primary site of the metastatic carcinoma could be gained . - pubmed
There were 80 patients with metastatic carcinoma , 14 with lymphoma , and 16 with myeloma . - pubmed
Hence , 27 of 30 myeloma or lymphomas were diagnosed by FNAB and in half of the patients with metastatic carcinoma the site of the primary tumor could be ascertained . - pubmed
For patients with a suspected skeletal metastasis the search for the primary tumor may preferably start with FNAB . - pubmed
SURGICAL TREATMENT : Risk factors for failure after operation for pathologic fractures were identified in 192 patients treated for 228 metastatic lesions of the long bones . - pubmed
Patients with a good prognosis should be considered for wide resection and reconstruction as applied in primary malignant bone tumors . - pubmed
To this end , the moral relevance of the difference between human embryos that have the potential for continued human growth and development and human embryos that do not have this potential is explored and a distinction between viable and non - viable IVF human embryos is introduced . - pubmed
On this basis , it is argued that scientifically and ethically sound research on spare non - viable IVF human embryos may proceed . - pubmed
METHODS : In 25 patients , 41 peri - implant defects with supporting bone loss & gt;50 % of the implant length were treated with flap surgery plus autogenous bone grafts alone ( FG ) ( controls , n = 12 ) plus non - resorbable ( FGM ) ( test 1 , n = 20 ) or bioabsorbable barriers ( FGRM ) ( test 2 , n = 9 ) and supportive antimicrobial therapy . - pubmed
Although there is little direct evidence that corticosteroid therapy can activate human malaria , animal studies have successfully demonstrated the recrudescence effect of immunosuppression on malaria infection . - pubmed
In this study , we monitored markers of automatic auditory processing in 15 female never - medicated psychotic patients . - pubmed
Prominent neurophysiological and behavioral signs of increased cortical activation were observed in psychotic patients . - pubmed
This report is focused on the apoptotic effect induced by MG132 , an inhibitor of 26S proteasome , in human hepatoma HepG2 cells . - pubmed
In fact , experimental models exist which demonstrate that soft tissue sarcomas can be induced in mice and rats by implanting artificial materials such as synthetics or metal . - pubmed
In conclusion , there are no data so far indicating a real risk for humans to develop malignant tumors due to implanted meshes . - pubmed
All patients received immunosuppressive therapy and non were on calcium and/or vitamin D supplements at the time of admission to our osteoporosis outpatient clinic . - pubmed
According to WHO criteria , osteoporosis at the femoral neck was present in 67 % ( 10/15 ) of the patients with a mean T - score of -2.55 + /- 0.35 . - pubmed
Secondary hyperparathyroidism ( 33 % ) , vitamin D deficiency ( 53 % ) as well as impaired renal function ( 47 % ) were frequent findings in the patients . - pubmed
In summary , we found a high prevalence of osteoporosis and vertebral fractures in liver transplant recipients with many of the patients showing evidence of vitamin D deficiency , secondary hyperparathyroidism and accelerated bone turnover . - pubmed
[ Assessment of function of the only kidney in children after nephrectomy due to Wilms tumor ] . - pubmed
UNLABELLED : The aim of the study was to evaluate kidney function in children after unilateral nephrectomy caused by Wilms ' tumour . - pubmed
The study included 40 former patients of the Department of Paediatric Surgery , who underwent complex therapy of Wilms ' tumour at the age from 6 months to 8 years ( mean 3.42 + /- 2.5 years ) . - pubmed
Amino acid ratios in plasma and tissues in a rat model of liver cirrhosis before and after exercise . - pubmed
In human liver cirrhosis ( LC ) , the Fischer ratio ( branched - chain amino acid ( BCAA)/aromatic amino acid ( AAA ) ) is used as a marker of hepatic encephalopathy . - pubmed
Nonmedical risk factors examined included race / ethnicity , age of acquisition of RSV , sex , birth during the first half of the RSV season , breast - feeding , malnutrition , maternal education , socioeconomic status , crowding / siblings , day care , and tobacco smoke exposure . - pubmed
RESULTS : There was sufficient evidence available to conclude that ( 1 ) male sex , ( 2 ) age & lt;6 months , ( 3 ) birth during the first half of the RSV season , ( 4 ) crowding / siblings , and ( 5 ) day care exposure are significant risk factors for severe RSV LRI . - pubmed
Low maternal education ( as a proxy for lower socioeconomic status ) , lack of breast - feeding , and malnutrition did not appear to increase the risk of severe RSV LRI or RSV hospitalization . - pubmed
CONCLUSIONS : Male sex , young age , birth in the first half of the RSV season , day care attendance , and crowding / siblings are independent risk factors for the development of severe RSV LRI . - pubmed
Carbamazepine ( CBZ ) is frequently used to treat patients with epilepsy , neuralgia , psychiatric diseases , etc . - pubmed
We describe the case of a 12 - year - old girl who exhibited half tone lowered pitch perception abnormality caused by CBZ . - pubmed
RT - PCR studies of lens RNA isolated from 129S1 / SvImJ , 129S2 / SvPas and 129S4 / SvJae strains confirmed the presence of this mutation in these diverse 129 strains and similar mutations were found in both CBA and 101 strains , but not in C3H or C57BL/6J mouse strains . - pubmed
The effects of Candida albicans on sperm parameters and the outcome of infertility treatment are unclear . - pubmed
This report describes a lack of fertilization after assisted reproductive techniques and increased sperm DNA fragmentation in an infertile patient with male accessory gland infection due to Candida albicans . - pubmed
Using a dot - matrix plotter as a tool to display pairwise comparisons of ordered predicted coding sequences along rice pseudochromosomes , we found that the rice genome contains extensive chromosomal duplications accounting for 53 % of the available sequences . - pubmed
Soon after completion of the BPRS , the events of September 11 occurred , followed by the human cases of anthrax . - pubmed
Experimental crescentic glomerulonephritis ( known as autologous anti - glomerular basement membrane glomerulonephritis ) induced by planting an antigen in glomeruli of mice is Th1 directed , delayed - type hypersensitivity ( DTH)-like , and antibody independent . - pubmed
Isolation of ani - hepatotoxic principle form the juice of Ecballium elaterium . - pubmed
The antihepatotoxic activity of elaterium ( dried juice of the fruits of Ecballium elaterium , Cucurbitaceae ) and cucurbitacin B ( isolated from the juice ) was studied against CCl4 - induced hepatotoxicity . - pubmed
Sindbis virus ( SINV ) is widespread in Europe , Africa , Australia , and Asia , but clinical infection occurs as epidemics in a few geographically restricted areas . - pubmed
We recently proved , by virus isolation from patients , that SINV is the causative agent of Pogosta disease , a mosquito - borne rash - arthritis occurring as larger epidemics every seventh year in Finland . - pubmed
SINV RNA detection or virus isolation from blood and/or skin lesions was successful in 8 patients . - pubmed
This was a retrospective review of 45 patients with small bowel neoplasm over a 20 - year period . - pubmed
BACKGROUND : Primary acquired melanosis ( PAM ) presents as a unilateral patchy area of conjunctival pigmentation mostly found in middle - aged or elderly white patients . - pubmed
CASE REPORT : A 72 - year - old white man presented for his annual examination with no visual complaints . - pubmed
The mean age of hypertensive adults was 52 years ( range 43 - 66 ) . - pubmed
Simple experiment for testing the effect of Antibiotic - EDTA combination on Rabbits skin artificial ulcer(s ) infected by Ps . - pubmed
[ The mechanism and significance of cellular signal transduction in kidney glomerular mesangial cells of rat with obstructive jaundice ] . - pubmed
Except the control and the sham operation group , the other two experiment groups underwent the common bile duct bound to form the rat model of obstructive jaundice . - pubmed
To investigate this process we established mouse models of sterile injury and explored the role of hyaluronan in mediating inflammation following injury . - pubmed
In the late phase study after 2000 ( n=16 ) , anticoagulant treatment to prevent graft necrosis was performed in the patients having a pHi value under the critical level . - pubmed
RESULTS : In the early phase study , vascular obstruction was not seen in 16 patients with pHi>7.10 . - pubmed
Of 3 patients with pHi<7.10 , 2 underwent regrafting because of jejunal graft necrosis by vascular obstruction . - pubmed
Intraoperative vascular occlusion was found in 1 patient with a decline in pHi value and anticoagulant treatment was effective in 2 others . - pubmed
The management of the patient and potential causes for the radiculopathy are discussed . - pubmed
The case acts as a reminder that the spinal nerve roots should be considered when performing intra - articular facet joint injections and demonstrates the importance of including nerve injury in the patient consent process as a rare , but significant complication . - pubmed
Usefulness of the two to 5 MHz ultrasound probe in examination and block of the sciatic nerve in orthopedic trauma patients : a preliminary study . - pubmed
METHODS : Immunocompetent BALB / c mice bearing Meth A fibrosarcoma were established . - pubmed
Interventions to decrease the ambulatory venous hypertension can help patients with either active or healed ulcers . - pubmed
In summary , compared with rHDLwt , rHDL74 and rHDL52 exhibit higher anti - inflammation capabilities , whereas rHDL228 shows hyper - proinflammation by exacerbating LPS - induced endotoxemia in mice . - pubmed
METHODS : Cartilage was obtained from patients with osteoarthritis ( OA ) who were undergoing joint replacement ; normal cartilage was obtained from cadavers who had no history of joint disease . - pubmed
Out of the patients from three hospitals who had microbiologically or histopathologically confirmed tuberculosis , 56 patients presenting with typical disseminated pulmonary nodules on radiographs were retrospectively enrolled . - pubmed
[ The study of therapeutic effect of synthetic bradykinin " gene " contained in retrovirus vector on spontaneously hypertensive rats ] . - pubmed
Administration of DNA plasmid pPS-3 - neo ( brd ) with synthetic bradykinin " gene " to 2 - days old male spontaneously hypertensive rats ( SHR ) leads to 2 weeks delay in development of arterial hypertension . - pubmed
This data indicate one of possible ways of gene therapy of arterial hypertension as well as other pathological states by introduction of transgene directly into genome of the organism . - pubmed
Morbidity , mortality , mean survival , and the impact of histology on survival after pleurectomy in 64 patients with malignant pleural mesothelioma . - pubmed
To date , the optimal procedure for resection of malignant pleural mesothelioma is controversial , extrapleural pneumonectomy has been most consistently associated with long - term survival and has provided the most radical cytoreduction ; but , unfortunately , not all patients qualify for this invasive surgical approach . - pubmed
METHODS : Between 1992 and 2000 , 64 patients underwent pleurectomy as a palliative treatment for MPM . - pubmed
Non - invasive assessment of endothelial activity in patients with coronary heart disease and cardiovascular risk factors . - pubmed
The majority of BP patients are elderly , and several considerations need to be taken into account before a specific therapy is chosen . - pubmed
We report our multi - surgeon experience of 43 consecutive patients ( 44 hips ) who received systemic vancomycin for two weeks in combination with a vancomycin- and gentamicin - eluting spacer system in the course of a two - stage revision procedure for deep infection with a median follow - up of 49 months ( 25 to 83 ) . - pubmed
Successful elimination of the infecting organisms occurred in 38 ( 92.7 % ) of 41 hips with three patients developing superinfection with a new organism . - pubmed
This dual receptor strategy illuminates the natural infection and inter - human propagation of this lymphotropic virus . - pubmed
Five hundred twenty - three human subjects ( 412 with no colonic neoplasia and 111 with colorectal cancer , who were scheduled for colonoscopy or surgery ) were recruited to donate a single sample of stool . - pubmed
These results indicate that ( 1 ) H magnetic resonance spectroscopy of human fecal extracts , combined with appropriate data analysis methodology , has the potential to detect colorectal neoplasia accurately and reliably , and could be a useful addition to the current screening tools . - pubmed
We present a 35 - year - old woman who suffered from headache and dizziness initially , and then lower back pain , lower limb weakness and paraparesis gradually developed within 1 - 2 weeks . - pubmed
PURPOSE : To describe a patient with a history of epithelial basement membrane dystrophy who developed symptomatic corneal verticillata after vandetanib therapy for anaplastic astrocytoma . - pubmed
The patient remained under surveillance for tumor recurrence . - pubmed
Tubifex tubifex are obligate invertebrate hosts in the life cycle of Myxobolus cerebralis , the myxozoan parasite that causes whirling disease in salmonid fishes . - pubmed
There was a significant difference in prevalence of infection and level of parasite production among the populations we exposed to M. - pubmed
The distribution and infection dynamics of susceptible T. - pubmed
These functions are essential for normal embryo development in flies and mice , and mutations or altered expression of SAGA subunits correlate with neurological disease and aggressive cancers in humans . - pubmed
Cytotoxic effects were compared using a colony - formation assay in three established cell lines ( Balb 3T3 , mouse whole embryo , ARLJ301 - 3 , rat liver and FRSK , rat keratinocytes ) and one primary cell culture ( RC-1 , rabbit cornea ) with the Draize eye irritancy score in vivo . - pubmed
Time trends of syphilis and HSV-2 co - infection among men who have sex with men in the German HIV-1 seroconverter cohort from 1996 - 2007 . - pubmed
We sought to explore trends in STI co - infections around the time of HIV seroconversion in patients from the German HIV-1 seroconverter cohort from 1996 - 2007 . - pubmed
Among HIV seroconverters with positive syphilis antibodies , 32 % ( n=88 ) were rated as having had coincident infections with HIV and syphilis . - pubmed
Coincident syphilis infection at HIV diagnosis increased substantially ( p<0.001 ) from 2.3 % in 2000 to 16.9 % in 2003 ; and thereafter declined to 4.3 % in 2007 . - pubmed
DISCUSSION : We found a stable prevalence of HSV-2 infection and increasing prevalence of syphilis infection around the time of HIV acquisition among MSM in Germany . - pubmed
Time course and rate of co - infections suggest that a re - emerging syphilis co - epidemic among MSM after 2000 could have contributed to an increase of HIV incidence by enhancing HIV transmission probability . - pubmed
METHODS : All patients diagnosed with pancreatitis consecutively underwent EUS on the 2nd day of their admission . - pubmed
Experiments of bone marrow transplantation between either genotype of mice showed that KO corneal tissue resident cells , but not KO bone marrow - derived cells , are responsible for KO - type wound healing with reduced inflammation and fibrosis . - pubmed
Middle and high trans - sphincteric fistulae were diagnosed in 20 ( 71.4 % ) and eight ( 28.6 % ) patients . - pubmed
No incontinence was found at a mean follow - up of 20.6 ( 3 - 60 ) months among the 67.8 % patients with no evidence of recurrence . - pubmed
MATERIALS AND METHODS : Eighteen biopsies of glioblastoma multiforme were obtained from patients at the Institute of Neurosurgery Dr. Asenjo ( INCA ) . - pubmed
RESULTS : The number of patients with glioblastoma multiforme increased between 2007 and 2009 , from 3.5 % to 7.9 % of total brain tumors . - pubmed
METHODS : In 112 consecutive patients with ASDs , the morphology of the defects was evaluated for transcatheter closure in the right parasternal view in addition to the conventional left views using 2D and 3D TTE . - pubmed
RESULTS : In 88 patients ( 80.0 % ) , optimal images from the right parasternal approach for morphologic evaluation of ASDs were obtained . - pubmed
Flexor tendon injuries still remain a challenging condition to manage to ensure optimal outcome for the patient . - pubmed
Subpopulation structure of regulatory T cells and T helpers of peripheral blood in patients with newly diagnosed pulmonary tuberculosis depending on the clinical form of disease and sensitivity of Mycobacterium tuberculosis to antituberculosis drugs has been analyzed in this work . - pubmed
In patients with infiltrative pulmonary tuberculosis , including multidrug - resistant M. - pubmed
Reduction in the number of T - helpers in the blood of patients with dissemination and fibrosis - cavity pulmonary tuberculosis mediates inefficient implementation of cell - mediated protective immunity . - pubmed
Free skin grafts for immediate wound coverage following tumour resection from the canine distal limb . - pubmed
METHOD : Evaluation of medical records of dogs that received a full - thickness , meshed , free skin graft in the distal limb immediately after tumour removal . - pubmed
None of the dogs had full thickness necrosis or required further reconstruction . - pubmed
CLINICAL SIGNIFICANCE : Free grafting can be used reliably to reconstruct extensive surgical wounds in the distal limb in dogs after large tumour resection without the need for a delay to allow granulation tissue to form . - pubmed
Effects of nasal insufflation on arterial gas exchange and breathing pattern in patients with chronic obstructive pulmonary disease and hypercapnic respiratory failure . - pubmed
High flow nasal insufflations ( NI ) can improve gas exchange and alleviate dyspnea in patients with acute respiratory failure . - pubmed
In the present study we investigated the effects of high flow nasal insufflations in COPD patients with chronic hypercapnic respiratory failure ( HRF ) . - pubmed
Seventeen patients with severe COPD and HRF were recruited . - pubmed
Our data indicate that high flow NI improved efficiency of breathing and may be used as an adjunct to low flow oxygen for preventing hypercapnic respiratory failure in severely ill COPD patients . - pubmed
Acute bilateral hearing loss as a " worsening sign " in a patient with critical basilar artery stenosis . - pubmed
We report a patient who presented with an acute - onset transient vertigo and unsteady gait with bilateral hearing loss . - pubmed
The neurological function of the patient recovered to normal , and no hemorrhagic complications were observed . - pubmed
Therefore , practitioners should be alert when treating patients with acute bilateral hearing loss , which may be related to an underlying catastrophic stroke . - pubmed
UNLABELLED : BACKGROUND : The foodborne pathogen Bacillus cereus can cause diarrhoeal food poisoning by production of enterotoxins in the small intestine . - pubmed
cereus strains were cultivated in a real composite food matrix , lasagne verde , and their survival during subsequent simulation of gastrointestinal passage was assessed using in vitro experiments simulating transit through the human upper gastrointestinal tract ( from mouth to small intestine ) . - pubmed
However , considerable strain variability was observed in sporulation tendency during growth in laboratory medium and food , which has important implications for the gastrointestinal survival potential of the different B. - pubmed
This paper reviews the literature concerning the influences of antidepressants in PWE and in animal models . - pubmed
Critically ill patients are frequently at risk of neurological dysfunction as a result of primary neurological conditions or secondary insults . - pubmed
Determining which aspects of brain function are affected and how best to manage the neurological dysfunction can often be difficult and is complicated by the limited information that can be gained from clinical examination in such patients and the effects of therapies , notably sedation , on neurological function . - pubmed
Methods to measure and monitor brain function have evolved considerably in recent years and now play an important role in the evaluation and management of patients with brain injury . - pubmed
Animals developed mixed dyslipidaemia and atherosclerotic lesions , which were associated with endothelial dysfunction , aortic overproduction of superoxide anions and inflammation . - pubmed
Within this context , reliable animal models that recapitulate situations of impaired wound healing have become essential . - pubmed
In this study , we established a new in vivo humanised model of delayed wound healing in a diabetic context that reproduces the main features of the human disease . - pubmed
Diabetes was induced by multiple low doses of streptozotocin in bioengineered human - skin - engrafted immunodeficient mice . - pubmed
OBJECTIVES / HYPOTHESIS : To investigate cochlear implantation ( CI ) in patients with unilateral deafness with and without tinnitus . - pubmed
STUDY DESIGN : Prospective case series of patients undergoing cochlear implantation for unilateral deafness and tinnitus in a tertiary academic unit . - pubmed
METHODS : Nine postlingually deafened subjects with unilateral hearing loss , with and without tinnitus ipsilaterally , and functional hearing in the contralateral ear were implanted with a standard electrode . - pubmed
CONCLUSION : In our case series , CI was successful for all nine patients , with improvement of speech recognition in noise , self - perceived improvement of hearing , and for tinnitus control . - pubmed
Compounds 1 , 4 and 5 exhibited good antibacterial activity against antibiotic resistant clinical bacteria and cytotoxic effects against selected cancer cell lines . - pubmed
METHODS : Forty - two patients treated with HR in 3 - 5 fractions for 20 ( 48 % ) intact and 22 ( 52 % ) resected brain metastases with a median maximum dimension of 3.9 cm ( 0.8 - 6.4 cm ) between May 2008 and August 2011 were reviewed . - pubmed
Symptomatic radiation necrosis occurred in 3 patients ( 7 % ) . - pubmed
Ninety - six smokers with and without PTSD provided blood samples for neurosteroid analyses and completed self - report measures of anxiety sensitivity and electronic diary ratings of negative affect . - pubmed
Anemia prevalence for the fortified rice center was 27.8 % ( 20/72 ) at baseline , and 11.1 % ( 8/72 ) at endpoint , p = 0.012 ; for the control center , 47.1 % ( 33/70 ) were anemic at baseline , and 37.1 % ( 26/70 ) at the end of the study , p = 0.23 . - pubmed
In animal studies , vitamin C has protected against various infections and bacterial toxins . - pubmed
In a study with rats , vitamin C protected against the purified tetanus toxin . - pubmed
This non - randomised , unblinded , controlled trial undertaken in Bangladesh involved 117 tetanus patients . - pubmed
In the tetanus patients aged 1 to 12 years ( n = 62 ) , vitamin C treatment was associated with a 100 % reduction in case fatality rate ( 95 % CI from -100 % to -94 % ) . - pubmed
METHODS : Charts of the patients with localised renal tumors , who were managed by either open or robot - assisted nephron - sparing surgery between May 2010 and June 2012 , were retrospectively reviewed . - pubmed
Effects of cooking methods on the iron and zinc contents in cowpea ( Vigna unguiculata ) to combat nutritional deficiencies in Brazil . - pubmed
BACKGROUND : Because iron deficiency anemia is prevalent in developing countries , determining the levels of iron and zinc in beans , the second most consumed staple food in Brazil , is essential , especially for the low - income people who experience a deficiency of these minerals in their diet . - pubmed
Here , through genome - wide identification of AS events in the soybean ( Glycine max ) genome using high - throughput RNA sequencing of 28 samples from different developmental stages , we found that more than 63 % of multiexonic genes underwent AS . - pubmed
Altogether , our study revealed that a large number of genes were alternatively spliced in the soybean genome and that variations in gene structure and transcriptional level may play important roles in regulating AS . - pubmed
Nongenotoxic effects and a reduction of the DXR - induced genotoxic effects of Helianthus annuus Linne ( sunflower ) seeds revealed by micronucleus assays in mouse bone marrow . - pubmed
BACKGROUND : This research evaluated the genotoxicity of oil and tincture of H. - pubmed
Accumulating evidence suggests that statins have pleiotropic effects ; therefore , these drugs could be a potential anti - inflammatory treatment for patients with bronchiectasis . - pubmed
We did a proof - of - concept randomised controlled trial to establish if atorvastatin could reduce cough in patients with bronchiectasis . - pubmed
INTERPRETATION : 6 months of atorvastatin improved cough on a quality - of - life scale in patients with bronchiectasis . - pubmed
Cardiovascular dysfunction and failure are commonly encountered in the patient with intra - abdominal hypertension or abdominal compartment syndrome . - pubmed
Application of a goal - directed resuscitation strategy , including abdominal decompression when indicated , improves cardiac function , reverses end - organ failure , and minimizes intra - abdominal hypertension - related patient morbidity and mortality . - pubmed
PURPOSE : Epstein - Barr virus ( EBV ) infects not only B cells but also T cells and natural killer ( NK ) cells , and T - and NK - cell lymphoproliferative diseases ( T / NK - LPD ) that are refractory to conventional chemotherapies may develop . - pubmed
Mogamulizumab induced antibody - dependent cellular cytotoxicity ( ADCC ) activity against CCR4 - positive cell lines , and inhibited the growth of EBV - positive NK - cell lymphomas in a murine xenograft model . - pubmed
EBV - positive gammadeltaT cells were obtained from a patient with hydroa vacciniforme and subjected to an antibody - dependent cell - mediated cytotoxicity ( ADCC ) assay . - pubmed
Chordomas of the upper cervical spine : clinical characteristics and surgical management of a series of 21 patients . - pubmed
This study aimed to describe the clinical characteristics and surgical management of patients with chordomas of the upper cervical spine . - pubmed
METHODS : Twenty - one patients with chordomas of the upper cervical spine who were treated in Peking University Third Hospital from January 1999 to October 2012 were retrospectively analyzed . - pubmed
Two patients developed postoperative velopharyngeal incompetence , and loosening of the occipitocervical screws was observed in one patient . - pubmed
Steroidal alkaloids from the marine sponge Corticium niger that inhibit growth of human colon carcinoma cells . - pubmed
Bioinformatic analysis of data from the NCI-60 cell cytotoxicity screen revealed a subset of extracts that showed selective cytotoxic activity toward human colon carcinoma cell lines . - pubmed
Bioassay - guided fractionation of a colon cancer selective extract from a Philippines collection of the marine sponge Corticium niger provided two new steroidal alkaloids , plakinamines N ( 1 ) and O ( 2 ) , along with two known compounds of the plakinamine class ( 3 , 4 ) . - pubmed
We therefore aimed to ascertain the prevalence of early repolarization pattern ( ERP ) in resting electrocardiograms ( ECGs ) of psoriatic patients compared with an appropriate control group . - pubmed
We performed a retrospective study of resting ECGs of 100 consecutive psoriatic patients and 100 healthy controls . - pubmed
An ERP in & gt;= 2 contiguous leads occurred in 40 % of psoriatic patients , compared with 14 % of control subjects ( p & lt ; 0.001 ) . - pubmed
Since CCRT with weekly chemotherapy regimens have demonstrated a favorable toxicity profile as well as promising survival in certain types of cancer , we aimed to evaluate the efficacy and toxicity of radiotherapy concurrently with weekly chemotherapy with 5 - fluorouracil ( 5 - FU ) and platinum agents for patients with postoperative locoregional recurrence of oesophageal squamous cell carcinoma in our center . - pubmed
Twenty - seven consecutive patients who were diagnosed with postoperative locoregional recurrence of oesophageal squamous cell carcinoma and received CCRT with weekly chemotherapy of 5 - FU and platinum agents were retrospectively analyzed . - pubmed
RESULTS : Of the 1450 patients who responded to both surveys and experienced no recurrence , 963 underwent breast - conserving surgery , 263 mastectomy without reconstruction , and 222 mastectomy with reconstruction . - pubmed
There are four main areas to focus on when thinking about management strategies in NAFLD : lifestyle modification , targeting the components of the metabolic syndrome , liver - directed pharmacotherapy for high risk patients and managing the complications of cirrhosis . - pubmed
Melatonin has been shown to diminish edema in rats . - pubmed
This study is a sequel of our earlier studies to understand the molecular organization of heat shock genes / proteins and their role in development and thermal adaptation in a sheep pest , Lucilia cuprina ( blowfly ) , which exhibits unusually high adaptability to a variety of environmental stresses , including heat and chemicals . - pubmed
Theory of mind and social functioning in patients with temporal lobe epilepsy . - pubmed
OBJECTIVE : This study aimed to explore the effects of theory of mind ( ToM ) and related potential risk factors , including cognitive functions , psychiatric status , and seizure - related clinical variables , on social functioning in patients with temporal lobe epilepsy ( TLE ) . - pubmed
METHODS : Sixty - seven patients with intractable TLE who were potential candidates for epilepsy surgery and 30 matched controls were included . - pubmed
Antiviral Efficacy of a Respiratory Syncytial Virus ( RSV ) Fusion Inhibitor in a Bovine Model of RSV Infection . - pubmed
Respiratory syncytial virus ( RSV ) is the leading cause of bronchiolitis and pneumonia in infants . - pubmed
Experimental infection of Holstein calves with bovine RSV ( bRSV ) causes a severe respiratory infection that is similar to human RSV infection , providing a relevant model for testing novel therapeutic agents . - pubmed
These data support the use of the bovine RSV model for evaluation of experimental therapeutics for treatment of RSV . - pubmed
Survival of rat cerebrocortical neurons after rickettsial infection . - pubmed
The main aim of this study was to investigate biochemical and morphological changes that may occur as a result of an in vitro infection of rat cerebrocortical neurons by selected members of the genus Rickettsia . - pubmed
Long - term remissions after FCR chemoimmunotherapy in previously untreated patients with CLL : updated results of the CLL8 trial . - pubmed
Despite promising results with targeted drugs , chemoimmunotherapy with fludarabine , cyclophosphamide ( FC ) , and rituximab ( R ) remains the standard therapy for fit patients with untreated chronic lymphocytic leukemia ( CLL ) . - pubmed
Herein , we present the long - term follow - up of the randomized CLL8 trial reporting safety and efficacy of FC and FCR treatment of 817 treatment - naive patients with CLL . - pubmed
First - line chemoimmunotherapy with FCR induces long - term remissions and highly relevant improvement in OS in specific genetic subgroups of fit patients with CLL , in particular those with IGHV MUT . - pubmed
In all patients , the putative arterial source of emboli was demonstrated by angiography . - pubmed
Intravenous Esomeprazole for Prevention of Peptic Ulcer Rebleeding : A Randomized Trial in Chinese Patients . - pubmed
This study aimed to evaluate a high - dose esomeprazole intravenous regimen vs. an active control ( cimetidine ) for the prevention of rebleeding in Chinese patients with a high risk of peptic ulcer rebleeding who had undergone primary endoscopic hemostatic treatment . - pubmed
CONCLUSION : In this phase 3 , multicenter , randomized trial conducted in China , esomeprazole showed a numerical trend towards superior clinical benefit over cimetidine in the prevention of rebleeding in patients who had successfully undergone initial hemostatic therapy of a bleeding peptic ulcer , with a similar safety and tolerability profile . - pubmed
In filarial nematodes , which include parasites responsible for major diseases of humans ( such as Onchocerca volvulus , agent of river blindness ) and companion animals ( Dirofilaria immitis , the dog heartworm ) , Wolbachia has an obligate mutualist role and is the target of new treatment regimens . - pubmed
Corrigendum to " Antimetastatic Potentials of Dioscorea nipponica on Melanoma In Vitro and In Vivo " . - pubmed
BACKGROUND : Noninvasive stress tests play a determinant role in the initial management of patients with chronic angina . - pubmed
Although the majority had normal EST results or an increased threshold to angina , at 1 month after the index PCI , 29 % of patients still had an abnormal result . - pubmed
CASE REPORT : The case is presented of a patient with diagnosis of iris nevus in the left eye in youth with a poor follow - up , who referred a decreased visual acuity in that eye . - pubmed
The present study investigated the effects of pulmonary exposure to single - walled carbon nanotubes ( SWCNTs ) and double - walled carbon nanotubes ( DWCNTs ) on atherosclerogenesis using normal human aortic endothelial cells ( HAECs ) and apolipoprotein E - deficient ( ApoE -/- ) mice , a model of human atherosclerosis . - pubmed
METHODS AND MATERIALS : We identified patients with adrenal metastases treated with SABR from 2009 to 2015 . - pubmed
RESULTS : Forty - three patients with 49 adrenal metastases ( 84 % from lung ) were treated with SABR to a median prescribed dose of 60 Gy in 10 fractions . - pubmed
PFS was better in patients with a solitary adrenal metastasis ( P = .03 ) . - pubmed
Low - grade gastrointestinal toxicity was common , but grade 2 toxicity was avoided in patients with a maximum stomach - bowel point dose of & lt;=50 Gy ( P = .03 ) . - pubmed
CONCLUSION : SABR was well tolerated and resulted in good 1 - year local control ; PFS was promising for patients with solitary metastases . - pubmed
METHODS : Multidimensional genomic profiling was performed in human aortic valves to document the expression of lncRNAs and the DNA methylation pattern in calcific aortic valve disease . - pubmed
One more time , renal biopsy showed tubular necrosis and patient recovered renal function after discontinuation . - pubmed
In all other cell lines , the concentration of metformin required to inhibit oxygen consumption acutely in vitro was substantially higher than that achieved in the plasma of diabetic patients . - pubmed
However , administering anti - diabetic doses of metformin to tumor - bearing mice resulted in intratumoral accumulation of metformin and reduced hypoxic tumor fractions . - pubmed
MATERIAL AND METHODS : In a project , evaluating patients with suspected chronic pancreatitis ( CP ) and healthy volunteers ( HC ) , stools were collected for 72 hours coupled to registration of nutritional intake over five consecutive days . - pubmed
RESULTS : We found 12 patients with CP , 11 patients without CP and 13 healthy individuals in our database . - pubmed
We used clinical outcome data from 493 cases of STEC O157 : H7 to assess the relative risk of severe disease including haemolytic uraemic syndrome from each of the defined clades in the population and show the dramatic effect Shiga toxin repertoire has on virulence . - pubmed
We describe two strain replacement events that have occurred in the cattle population in the UK over the last 30 years , one resulting in a highly virulent strain that has accounted for the majority of clinical cases in the UK over the last decade . - pubmed
Retrospective evaluation of factors influencing successful skin grafting for patients with skin cancer of the foot . - pubmed
We analyzed data for 71 patients with skin cancer of the foot who underwent reconstruction of defects with skin grafting . - pubmed
A 50 - year - old man experienced cardiac arrest . - pubmed
METHODS : A total of 162 subjects were categorized into four groups based on depression scores and blood pressure . - pubmed
Perineural tumor spread ( PNS ) substantially alters a patient 's prognosis and treatment plan . - pubmed
This study describes the development and initial evaluation of a multiplex reverse transcription ( RT)-PCR and novel accompanying automated electronic microarray assay for simultaneous detection and differentiation of seven important viruses that affect swine ( foot - and - mouth disease virus [ FMDV ] , swine vesicular disease virus [ SVDV ] , vesicular exanthema of swine virus [ VESV ] , African swine fever virus [ ASFV ] , classical swine fever virus [ CSFV ] , porcine respiratory and reproductive syndrome virus [ PRRSV ] and porcine circovirus type 2 [ PCV2 ] ) . - pubmed
This assay accurately detected and identified a total of 68 isolates of the seven targeted virus species including 23 samples of FMDV , representing all seven serotypes , and 10 CSFV strains , representing all three genotypes . - pubmed
Patients who undergo total hip arthroplasty ( THA ) may experience a large amount of blood loss . - pubmed
The circular extrachromosomal element of Naegleria gruberi strain EGB was linearized , molecularly cloned , and fully sequenced . - pubmed
A cohort of 710 patients with idiopathic dilated cardiomyopathy , without previous ventricular arrhythmias , was retrospectively studied to understand how risks vary in time . - pubmed
Genetic Association of Drug Response to Erlotinib in Chinese Advanced Non - small Cell Lung Cancer Patients . - pubmed
This study provides comprehensive , systematic analyses of genetic variants associated with responses to erlotinib in Chinese advanced non - small cell lung cancer patients . - pubmed
Newly - identified SNPs may serve as promising markers to predict responses and safety in erlotinib - treated advanced non - small cell lung cancer patients after chemotherapy doublet . - pubmed
METHODS : We performed a single - center retrospective analysis including 489 patients with ulcerative colitis . - pubmed
Detection in whole blood of autoantibodies for the diagnosis of connective tissue diseases in near patient testing condition . - pubmed
METHODS : A cross - sectional study was performed in 87 patients with TA and 90 controls . - pubmed
RESULTS : All the inflammatory markers were significantly higher in the TA patients than in the controls . - pubmed
INTRODUCTION : The survival of multiple myeloma patients is increasing due to new medications , the widespread implementation of autologous stem cell transplantation and better supportive treatments . - pubmed
Areas covered : In this review , we have summarized the current data on maintenance therapy in newly diagnosed MM patients undergoing ASCT , focusing on bortezomib , thalidomide and lenalidomide as well as newer agents Expert opinion : Maintenance treatment has been shown to deepen and prolong responses and increase PFS and OS . - pubmed
Propranolol is the first - line treatment for infants suffering from infantile hemangioma . - pubmed
Remodeling classification system considering left ventricular volume in patients with aortic valve stenosis : Association with adverse cardiovascular outcomes . - pubmed
CONCLUSIONS : In patients with AVA & lt;= 1.5 cm2 , when the new LV remodeling classification system is applied , only a minority had normal geometry and less than half had " classic " concentric LVH or remodeling . - pubmed
Grip force tracking tasks were conducted by stroke patients , age - matched healthy controls , and healthy young adults at 25 % , 50 % , and 75 % maximum voluntary contractions ( MVC ) , respectively . - pubmed
Circulating tumor DNA ( ctDNA ) holds great promise as a noninvasive diagnostic tool to guide treatment for patients with lung cancer . - pubmed
Together , these studies further highlight the potential clinical utility of serial ctDNA monitoring in patients with NSCLC undergoing treatment with both targeted therapies and immunotherapies . - pubmed
Recently , the putative association between selective serotonin reuptake inhibitor ( SSRI ) exposure during pregnancy and the development of social disorders in children has gained increased attention . - pubmed
Furthermore , preclinical studies using an animal model of maternal depression to study effects of perinatal SSRI exposure on offspring social behavior are limited . - pubmed
Here , we aimed to investigate whether different doses of atorvastatin ( ATV ) affect rats with T2DM . - pubmed
A total of 110 Sprague - Dawley rats were successfully established as T2DM models . - pubmed
Rats administered ATV at the doses of 40 and 80 mg/(kg day ) demonstrated significantly improved liver injury and pancreatic injury induced by T2DM . - pubmed
Conclusion : These data revealed that ATV could improve the lipid metabolism in T2DM rats and 40 mg/(kg day ) may serve as the optimal dose for the reduction of lipid levels and the incidence of adverse effects . - pubmed
Since mid-2015 , numerous outbreaks of hydropericardium - hepatitis syndrome ( HHS ) , which is caused by a novel fowl adenovirus serotype 4 ( FAdV-4 ) , have been reported in chickens in parts of China , thereby causing huge economic losses to the poultry industry . - pubmed
Thus , an effective vaccine to control the further spread of infections with this hyper - virulent FAdV-4 is imperative . - pubmed
In this study , we isolated a novel FAdV-4 strain SDJN0105 from a broiler farm with HHS disease in Shandong Province . - pubmed
These results improve our understanding of the innate immune responses in chickens infected with FAdV-4 and the pathogenesis of FAdV-4 caused by host factors , and the developed FAdV-4 vaccine is promising as a drug candidate for the prevention and reduction of the spread of HHS in poultry in China . - pubmed
BACKGROUND : Indications for revision surgery are unclear in refractory cubital tunnel syndrome patients , and the optimal surgical method has not been determined . - pubmed
In this study , fERG data were recorded from MDD patients in a current major depressive episode ( n = 25 ) , and compared to data from SCZ patients ( n = 25 ) and healthy controls ( HC ; n = 25 ) , to determine the degree to which fERG anomalies in acute MDD overlap or contrast with those observed in stabilized ( though not symptom free ) SCZ . - pubmed
Interestingly , MDD patients demonstrated an increase in photopic a - wave implicit time relative to SCZ patients , and a decrease in PhNR implicit time relative to controls . - pubmed
Patients and methods : This single - center cross - sectional study encompassed 201 patients ( 160 males , 41 females ; mean age 56.9 + -13 years ; range 20 to 89 years ) including 52 asymptomatic hyperuricemia , 86 gouty arthritis without tophi , and 63 gouty tophi patients . - pubmed
CONCLUSIONS : In patients with RA , the relative increase in etanercept - associated risk of experiencing congestive heart failure , serious infection , non - melanoma skin cancer , or interstitial lung disease was similar between elderly and non - elderly . - pubmed
The cytotoxicity of R. - pubmed
Exhaled Volatile Organic Compounds Precedes Pulmonary Injury in a Swine Pulmonary Oxygen Toxicity Model . - pubmed
Results : Swine exposed to hyperoxia developed pulmonary injury consistent with PO2T. - pubmed
Histology of oxygen - exposed swine showed pulmonary lymphatic congestion , epithelial sloughing , and neutrophil transmigration . - pubmed
Conclusion : Exposing swine to 72 h of hyperoxia induced a pulmonary injury consistent with human clinical endpoints of PO2T. - pubmed
Results show promise that a simple , non - invasive breath test could potentially predict the risk of pulmonary injury in humans exposed to high partial pressures of oxygen . - pubmed
Survival and ocular preservation in a long - term cohort of Japanese patients with retinoblastoma . - pubmed
BACKGROUND : Retinoblastoma is an ocular tumor in infants with cancer predisposition . - pubmed
METHODS : We studied the outcomes of all patients with retinoblastoma at a tertiary center in 1984 - 2016 , when preservation method changed from radiotherapy ( 1984 - 2001 ) to systemic chemotherapy ( 2002 - 2016 ) . - pubmed
RESULTS : One - hundred sixteen infants developed unilateral- ( n = 77 ) , bilateral- ( n = 38 ) , or trilateral - onset ( n = 1 ) tumor . - pubmed
The 10 - year OS and cancer ( retinoblastoma / SPM)-free survival ( CFS ) rates of all patients were 94.9 and 88.5 % , respectively . - pubmed
METHODS : In this study , we analyzed the pooled data of 109 PAD patients enrolled in the SHIFT and IBIS studies . - pubmed
RESULTS : The total monthly SCIG dose showed comparable trends among weight categories , except for underweight patients . - pubmed
Methods : A total of 120 NSG mice were used for a combined pharmacodynamics and toxicity study for 56 days . - pubmed
The survival rate and leukemia related clinical symptoms in mice administered CART19 were markedly ameliorated , and the proliferation of Raji cells in mice was effectively inhibited . - pubmed
Conclusions : NSG mice given CART19 treatment demonstrated a longer survival period without significant immunotoxicity , suggesting encouraging clinical prospects for CART19 in patients with R / R ALL . - pubmed
WD - fed knockout mice developed severe NASH , which was associated with increased BA concentration in the cecum and loss of CEB function . - pubmed
Orbitides isolated from flaxseed induce apoptosis against SGC-7901 adenocarcinoma cells . - pubmed
In this study , we investigated the effects of orbitides isolated from flax ( Linum usitatissimum L. ) on the growth of SGC-7901 cancer cells and the potential mechanism . - pubmed
OBJECTIVE : The objective was to assess the effects of a nasal restriction device for inspiratory muscle training , called Feelbreathe , added to a rehabilitation program ( RP ) on exercise capacity , quality of life , dyspnea and inspiratory muscle strength in patients with stable COPD . - pubmed
The presented data identifies new leads to understand the mechanisms behind brain and specifically cortical development and can provide novel insights in developmental mechanisms underlying human brain defects . - pubmed
OBJECTIVES : The purpose of this pilot porcine cadaver study was to evaluate the feasible temperature thresholds , which affect osteocyte viability and bone matrix in a preclinical setup , assessing the potential of thermal necrosis for implant removal for further in vivo investigations . - pubmed
[ Expression and diagnostic value of plasma miR-145 and miR-183 in children with lupus nephritis ] . - pubmed
OBJECTIVE : To study the expression and diagnostic value of plasma miR-145 and miR-183 in children with lupus nephritis ( LN ) . - pubmed
METHODS : A total of 92 children with LN who were admitted from January 2016 to May 2019 were enrolled as the LN group , among whom 17 had type II LN , 15 had type III LN , 36 had type IV LN , 18 had type V LN , and 6 had type VI LN . - pubmed
According to Systemic Lupus Erythematosus Disease Activity Index ( SLEDAI ) , the 92 children with LN were further divided into a stable LN group with 34 children ( SLEDAI score < 10 ) and an active LN group with 58 children ( SLEDAI score > = 10 ) . - pubmed
CONCLUSIONS : There are significant reductions in the expression levels of miR-145 and miR-183 in plasma in children with LN , which are correlated with the activity level and pathological typing of LN . - pubmed
BACKGROUND AND PURPOSE : Differentiation between pseudo - occlusion and true occlusion of internal carotid artery ( ICA ) is important in treatment planning for acute ischemic stroke patients . - pubmed
We compared the findings of multiphasic computed tomography angiography between cervical ICA pseudo - occlusion and true occlusion at the cervical ICA in patients with anterior circulation acute ischemic stroke to determine their diagnostic value . - pubmed
Whereas LHb inactivation did not modify rat 's behavior during conditioning , it induced contextual memory deficits and enhanced fear to the tone . - pubmed
QTcD has been shown to be higher in individuals with mild cognitive impairment , and the highest in individuals with Alzheimer ' s disease . - pubmed
This study aimed to assess vagal control in VVS patients and evaluate the diagnostic value of the DC in VVS . - pubmed
Methods - Altogether 161 consecutive VVS patients ( 43 + - 15 years ; 62 males ) were enrolled . - pubmed
DC was similarly increased in VVS patients with a positive and negative TTT ( 9.7 + -3.5 ms and 9.4 + -2.9 ms , P=0.614 ) . - pubmed
Letter to the Editor Regarding : " Effects of exercise in patients with amyotrophic lateral sclerosis : A systematic review and meta - analysis " . - pubmed
According to the recent studies , these derivatives exhibited good antiviral activity against different types of viruses such as the human immunodeficiency viruses ( HIV ) , the hepatitis C virus ( HCV ) , the hepatitis B virus ( HBV ) , Respiratory syncytial virus ( RSV ) , and Cytomegalovirus ( CMV ) . - pubmed
Methods Patients with chronic hepatitis B were treated with pegylated interferon alpha-2a for 48 weeks . - pubmed
METHODS : Our study retrospectively recruited advanced CM ( clinical T3 stage ) patients treated with individualised ( 13 cases ) or conventional ( 18 cases ) exenteration from June 2014 to April 2019 . - pubmed
Newborn mice sensitized to picryl chloride within 24 hr after birth fail to develop contact sensitivity reaction when tested several weeks later , and fetal mice do not develop graft - versus - host reaction when given injections of parental lymphocytes . - pubmed
Spleen cells of fetal or newborn mice are able to suppress the passive transfer of contact sensitivity and the local graft - versus - host reaction elicited by immunized parental cells in F1 hybrid mice , and reduce significantly the severity of graft - versus - host reaction and mortality rate in cyclophosphamide - treated F1 recipients . - pubmed
of urapidil , there was no hypotensive effect in the rat to be seen and , therefore , it can be concluded that changes in spontaneous and reactive behaviour are not due to acute changes in cardiovascular functions . - pubmed
Tallysomycin exhibited broad antibacterial and antifungal activity , and was highly active in vivo against bacterial infections in mice . - pubmed
A comparison between blood glucose levels in patients attending a diabetes clinic and in the same patients leading their normal lives showed that for maturity - onset diabetic patients on oral hypoglycemic therapy , the clinic levels were a poor guide to the patients ' usual blood glucose . - pubmed
Invasive prostatic patterns are most frequent in the setting of high stage invasive bladder tumors and 5 - year survival rates for these patients are low . - pubmed
Fenfluramine - induced hyperthermia and stimulation in the rabbit . - pubmed
Fenfluramine produces dose - related hyperthermia and behavioral stimulation in rabbits following intravenous administration . - pubmed
Early postoperative thrombosis of the prosthesis occurred in 7 patients . - pubmed
Late thrombosis of the aorto - renal branch or aorto - femoral prosthesis occurred in 4 patients . - pubmed
The clinical course of chronic lymphocytic leukaemia ( CLL ) in 126 patients has been examined over the period 1961 - 88 . - pubmed
In fact periodontal disease is caused by specific bacteria ( Bacteroides Gingivalis , Actinobacillus actinomycetemcomitans ) growing in the periodontal pocket so that the bacterial products such as histolytic enzymes , endotoxins or exotoxins may exert a direct effect . - pubmed
Anteroapical left ventricular aneurysms were produced in 23 sheep by coronary arterial ligation . - pubmed
In nine of these sheep the midsagittal plane of the left ventricle was imaged by means of an array of sonomicrometry crystals before and after plication of the aneurysm . - pubmed
Lacrimal and salivary gland inflammation in the C3H / Ipr autoimmune strain mouse : a potential mode for Sjogren ' s syndrome . - pubmed
To identify a potential animal model for study of Sjogren ' s syndrome , an evaluation was made of lacrimal and salivary glands in the C3H / Ipr autoimmune strain mouse at ages before ( 2 months ) and after ( 5 months ) systemic autoimmune disease onset at 3 to 4 months . - pubmed
Quantitative and qualitative analyses of C3H / Ipr lacrimal and salivary ( parotid , submandibular , and sublingual ) gland histopathology were performed using age - matched C3H / HeJ nonautoimmune mice to control for inflammation of nonautoimmune origin . - pubmed
A significant increase in lacrimal gland inflammation was found in the 5 month old C3H / Ipr autoimmune mice in a histologic pattern similar to that of Sjogren ' s syndrome in human beings . - pubmed
Sporadic inflammation of the submandibular gland was seen in both autoimmune and control mice , but this was neither statistically significant nor correlated with measures of autoimmunity . - pubmed
Sensitivity of cerebellar Purkinje neurons to neurotransmitters in genetically epileptic rats . - pubmed
We have conducted experiments using microiontophoresis with in situ extracellular recording of anesthetized rat cerebellar Purkinje neuron activity to determine the sensitivity of these neurons to neurotransmitters in a genetic model of epilepsy . - pubmed
Current - response curves were generated and linear regression analysis was performed to evaluate changes in responsiveness and sensitivity between control and genetically epilepsy - prone-9 rats . - pubmed
The current required to produce 50 % inhibition of activity by GABA was 2.6 - fold higher in the genetically epilepsy - prone-9 rats compared to control . - pubmed
We present a case report of a patient with an isolated dissection of the subclavian artery after blunt trauma . - pubmed
The patient who was admitted to our center after a motor vehicle accident , complained of chest and neck pain and physical findings of diminished left extremity pulses . - pubmed
The porcine cauda equina would also be particularly suitable for chronic compression studies because any neurologic deficit acquired would be restricted to the tail . - pubmed
After curative resection of colorectal cancer , immediate short - term postoperative intraportal adjuvant chemotherapy reduces the relative risk of recurrence and death in the non - transfused patient significantly , when compared to transfused patients without chemotherapy . - pubmed
The transfused patients with chemotherapy and those receiving neither transfusions nor chemotherapy had a relative risk of recurrence and death situated in between the two groups mentioned above , not statistically different from either of them . - pubmed
[ Cardiac lipoma in a patient with diffuse subcutaneous lipomatosis . - pubmed
We describe a case of left ventricular intramyocardial lipoma in a patient with diffuse subcutaneous lipomatosis . - pubmed
The four strains of E. - pubmed
Second bone marrow transplantation after leukemia relapse in 11 patients . - pubmed
Since June 1977 eight patients with acute leukemia and three with chronic myelogenous leukemia ( CML ) have undergone cytoreductive therapy prior to a second allogeneic or syngeneic bone marrow transplantation ( BMT ) . - pubmed
Of seven patients who survived beyond 1 year , two patients subsequently died , one as a result of acute respiratory failure and one of leukemia relapse . - pubmed
In this patient population which is at high risk for resistant disease and treatment - related toxicity , a second preparative therapy and BMT may offer a durable disease remission with tolerable toxicity . - pubmed
Intracranial compliance , as estimated from a computerized frequency analysis of the intracranial pressure ( ICP ) waveform , was continuously monitored during the acute postinjury phase in 55 head - injured patients . - pubmed
In 12 patients who developed uncontrollable intracranial hypertension or clinical signs of tentorial herniation during the monitoring period , 75 % were observed to have had an increase in the HFC to 9.0 Hz or more 1 to 36 hours prior to the clinical decompensation . - pubmed
We performed clinical analysis of 12 patients with renal cell carcinomas associated with tumor thrombosis in the inferior vena cava . - pubmed
Surgery could not be performed in the other 3 patients of their poor general condition or severe heart disease . - pubmed
One patient died because of massive hemorrhage during the operation . - pubmed
In 4 patients without distant metastases or regional lymph nodes metastasis , two died of multiple metastasis of renal cell carcinomas and diabetic coma . - pubmed
Balb / c ( H-2d ) mice were transfused at weekly intervals with whole blood from donors of three strains using two transfusion protocols . - pubmed
Thoracolumbosacral laminectomy in achondroplasia : long - term results in 22 patients . - pubmed
Preoperatively , 91 % of patients had motor function impairment , 86 % had sensory dysfunction , 86 % had neurogenic claudication , 77 % had radicular pain , 59 % had symptomatic bladder dysfunction , and 32 % had fecal incontinence . - pubmed
However , some patients have , or later develop , compression adjacent to the myelographic site of stenosis , and some develop hypertrophic scarring at the site of initial decompression . - pubmed
During the OGTT , the post - glucose plasma glucose values in the diabetic patients were markedly higher ( P less than 0.001 ) than in the normal subjects . - pubmed
Late results of epilepsy treatment in 150 children hospitalized in the Department of Psychiatry , Institute of Paediatrics , Medical Academy in Warsaw and followed - up in the outpatient clinic of this Department are described . - pubmed
Physiological changes under elemental diet have been reported : decrease of gastric and pancreatic secretion , changes of bacterial bowel flora and in patients with Crohn ' s disease decreased fecal bile acid excretion and decreased intestinal losses of lymphocytes were described . - pubmed
Eight infants with complex cardiac anomalies and pulmonary stenosis or atresia were noted to have obstructed total anomalous pulmonary venous drainage ( TAPVD ) either at the initial cardiac catheterization ( Group 1 ; n = 2 ) or after creation of systemic - pulmonary artery shunts ( Group 2 ; n = 6 ) . - pubmed
The 2 patients in Group 1 underwent early repair of TAPVD ( 1 at 7 days , the other at 1 1/2 months of age ) before any subsequent operation and are now doing well at 18 months of age . - pubmed
The 6 patients in Group 2 underwent repeat cardiac catheterization because of persistent severe cyanosis with faint or absent continuous murmur and were found to have patent shunts and obstructed TAPVD ( 1 mild , 5 severe ) . - pubmed
One patient who underwent repair of TAPVD at 2 1/2 months of age survived and is well at 2 years of age , whereas 4 patients who underwent repair at an average age of 6 months ( age range , 3 - 16 months ) subsequently died . - pubmed
[ Cytologic study of the cerebrospinal fluid in leukemia patients with neurologic symptoms ] . - pubmed
[ Content and intensity of metabolism of free nucleotides , nucleic acids , phosphoproteins and phospholipids of the liver in experimental atherosclerosis in rabbits ] . - pubmed
The tumor promoter phorbol myristic acetate ( PMA ) also enhances RNA synthesis and Ia antigen expression in B cells from both normal and CBA / N mice . - pubmed
I describe three patients with orthostatic tremor that involved mainly the legs and trunk and was not present when the patients walked , sat , or lay down . - pubmed
An enzyme - linked immunoassay ( ELISA ) was developed to study syngeneic humoral immune response to a primary tumor and its metastases in the K-1735 ultraviolet light ( UV)-induced C3H murine melanoma system . - pubmed
Binding of sera from syngeneic animals previously immunized with primary tumor or metastatic tumor tissue ( M-3 , M-4 ) to corresponding 3 M KCl extracts of tumor was significantly greater than binding of control C3H mouse serum . - pubmed
Antibody binding was not significantly reduced by competitive binding with syngeneic murine muscle or liver extracts , indicating the presence of tumor antigen(s ) not shared by normal murine tissue . - pubmed
Antibodies to the tumor - associated antigens were selectively removed by competitive binding with syngeneic K-1735 tumor extracts but not by the unrelated 102 murine sarcoma from C57BL / 6 . - pubmed
[ Role of nursing in the care of an epileptic patient ] . - pubmed
A 53 - year - old man with a traumatic dural arteriovenous fistula between the middle meningeal artery and the adjacent cortical vein is reported . - pubmed
Fetal blood flow velocity waveforms of the middle cerebral artery were measured by pulsed Doppler ultrasound in 43 pregnant women with diabetes mellitus ( 33 class B , 3 class C , 6 class D and 1 class R ) . - pubmed
DESIGN : We undertook a retrospective analysis on 396 patients with chronic limb pain referred for autonomic testing during a 5 - year period . - pubmed
Because certain physiologic trends occur in all patients , general alterations of autonomic function with pain are suggested . - pubmed
( 1991 ) have reported that in our mouse model system a membrane - associated 44 - kDa acetaminophen - binding protein is the earliest target detected immunochemically following administration of an hepatoxic dose of APAP . - pubmed
Thigmotaxis as an index of anxiety in mice . - pubmed
We have considered the degree of thigmotaxis during this period of decrease as an index of anxiety in mice . - pubmed
A retrospective analysis was performed of 48 patients with hyperthyroidism ( 41 women aged 35 - 80 , mean 56.6 years ; 7 men aged 31 - 77 , mean 52.1 years ) treated with a fixed dose of 550 MBq 131I during a 12 month period May 1991 - April 1992 . - pubmed
[ Nutrition disorders in fattening pigs in an " organic " facility ] . - pubmed
In a herd of fattening pigs under an organic system of management , the following problems were observed : sudden deaths , skin diseases , diarrhea , increased restlessness and cannibalism . - pubmed
The response of a human tumor cell line to low radiation doses : evidence of enhanced sensitivity . - pubmed
The survival of asynchronous , exponentially growing DU-145 human tumor cells was measured after single doses of X rays in the dose range of 0.05 - 4 Gy using the cell sorting assay . - pubmed
The efficacy rate of 2 - 4 g / day of CDZM drip infusion against infections was 53/56 ( 94.6 % ) while the bacterial eradication rate was 36/38 ( 94.7 % ) . - pubmed
Patients with a parenchymal hemorrhage volume of 60 cm3 or more on their initial computed tomogram and a Glasgow Coma Scale score of 8 or less had a predicted 30 - day mortality of 91 % . - pubmed
Only one of the 71 patients with a volume of parenchymal hemorrhage of 30 cm3 or more could function independently at 30 days . - pubmed
CONCLUSIONS : Volume of intracerebral hemorrhage , in combination with the initial Glasgow Coma Scale score , is a powerful and easy - to - use predictor of 30 - day mortality and morbidity in patients with spontaneous intracerebral hemorrhage . - pubmed
Ten patients had on 2 occasions serum calcium levels below or equal to 2 mmol / L and were defined as having severe hypocalcemia . - pubmed
Severe hypocalcemia was found in 8 patients after total thyroidectomy , compared with 2 after hemithyroidectomy ( p & lt ; .05 ) , and was present in 3 of the 5 patients with thyroid carcinoma , compared with 7 of the 90 patients with nonmalignant thyroid diseases ( p & lt ; .01 ) . - pubmed
No patients had persistent symptoms of hypocalcemia from 2 to 3 months after surgery . - pubmed
Metabolic disorders of cattle . - pubmed
Goldberger discovered human pellagra was a non - infectious disease , affecting mostly the small and the timid in overcrowded institutions . - pubmed
There is a diminished uptake of glucose by the tissues , a condition also found in parturient paresis of dairy cows when elevated hydrocortisone promotes insulin resistance and hyperglycaemia . - pubmed
The major predisposing factor in parturient paresis of dairy cows is hypocalcaemia . - pubmed
[ Low - dose midazolam reduces the alfentanil demand in elderly but not in young patients during extracorporeal shock wave lithotripsy ] . - pubmed
To evaluate whether midazolam has analgesic properties in humans after intravenous injection we studied the influence of a subhypnotic dose of midazolam ( 50 micrograms / kg ) on the cumulative alfentanil consumption in 53 patients during extracorporeal shock wave lithotripsy ( ESWL ) using a patient - controlled analgesia system ( PCAS ) . - pubmed
Clinical and pathological features of thoracic neoplasia in the horse . - pubmed
Thirty - eight horses with confirmed thoracic neoplasia included 28 ( 37.7 % ) with lymphosarcoma , 4 ( 10.5 % ) with metastatic renal cell carcinoma , 2 ( 5.3 % ) with primary lung carcinoma , 2 ( 5.3 % ) with secondary squamous cell carcinoma from the stomach , 1 ( 2.6 % ) with pleural mesothelioma , and 1 ( 2.6 % ) with malignant melanoma . - pubmed
[ Effect of propafenone hydrochloride on atrial signal - averaged ECG in patients with paroxysmal atrial fibrillation ] . - pubmed
Oral propafenone hydrochloride effect was studied on atrial signal - averaged ECG ( ASAECG ) during time- and frequency - domain analysis in patients with paroxysmal atrial fibrillation ( PAF ) during ischemic heart disease ( IHD ) . - pubmed
Our observation have indicated that oral propafenone therapy does not influence any statistically significant differences all time- and frequency - domain parameters of ASAECG in patients with PAF during IHD . - pubmed
BACKGROUND : Cost - effective therapy that heals ulcers rapidly and prevents recurrence would significantly impact patient care and the health system . - pubmed
OBJECTIVE : To evaluate compression stockings for treatment of venous ulcerations and prevention of recurrent ulceration ; to analyze patient compliance ; and to evaluate cost of compression stocking therapy . - pubmed
METHODS : Stocking therapy healed venous ulcers in 53 patients . - pubmed
RESULTS : Twenty - five patients had good stocking usage ; one developed recurrence ( 4 % ) . - pubmed
Qualitative and quantitative characteristics of chronic pain syndrome and their possible use in assessing analgetic effects of treatment were studied in 16 , 49 , 26 and 17 patients with gastric ulcer , duodenal ulcer , chronic pancreatitis , chronic colitis , respectively . - pubmed
These results suggest that RA may be suitable for the treatment of patients with adult T cell leukemia ( ATL ) . - pubmed
Human bite mark evidence is often found in violent crimes . - pubmed
Patients with early - stage tumors not requiring adjuvant radiation therapy attain long - term function comparable to that of patients who have had an IPAA for benign disease . - pubmed
Exposure of metronidazole - resistant ( MtzR ) strains of H. - pubmed
PURPOSE : To evaluate the technical possibility of creating a percutaneous retroperitoneal splenorenal shunt ( PRESS ) in swine as a minimally invasive treatment of portal hypertension . - pubmed
Finally , the use of inhaled corticosteroids results in the control of asthma , allowing patients to exercise , which itself improves bone density and protects against osteoporosis . - pubmed
We studied saccade and smooth pursuit eye movements in 31 patients suffering from myotonic dystrophy ( MD ) . - pubmed
Since D5 / D35 dissociation occurred in 26/33 multiple sclerosis patients with increased saccade duration , we considered it to be a neurogenic pattern attributable to a central nervous system ( CNS ) dysfunction . - pubmed
Accordingly we classified the oculomotor abnormalities detected as neurogenic in 11 MD patients and as myogenic in another 10 , but in some subjects belonging to the second group concomitant CNS impairment is not to be excluded . - pubmed
We evaluated 138 relatively unselected patients with peripheral neuropathy who underwent neurologic evaluation , electromyography ( EMG ) , nerve conduction studies , and autonomic function tests to determine which variables were predictive of laboratory findings of autonomic failure . - pubmed
We conclude that autonomic studies will most likely be abnormal in patients who have symptoms of autonomic involvement and those who have an axonal neuropathy . - pubmed
All animals were re - explored 14 days later , and the abdominal cavity was examined for adhesions . - pubmed
DOCA - salt hypertension was induced in 8 - wk - old male Wistar rats by uninephrectomy and administration of DOCA ( 25 mg every fourth day , subcutaneously ) and 1 % NaCl in the drinking water for 4 wk . - pubmed
The objective of this work was to explore if an interaction with beta - blocker treatment plays a role in the decrease of cardiac arrhythmic deaths with amiodarone in patients recovered from an acute myocardial infarction . - pubmed
Unadjusted and adjusted relative risks for all - cause mortality , cardiac death , arrhythmic cardiac death , nonarrhythmic cardiac death , arrhythmic death , or resuscitated cardiac arrest were lower for patients receiving beta - blockers and amiodarone than for those without beta - blockers , with or without amiodarone . - pubmed
Interrelation between cerebral energy metabolism and behaviour in a rat model of permanent brain vessel occlusion . - pubmed
The data of the present study demonstrate a linear relationship between cerebral energy metabolism and brain memory capacities after acute and permanent vessel occlusions in rats . - pubmed
RESULTS : During the prospective six - month phase , 84 confirmed stroke patients were transported to the target hospitals . - pubmed
Induction of hyperplasia and increased DNA content in the uterus of immature rats exposed to coumestrol . - pubmed
In addition , bromodeoxyuridine staining of uterine sections enabled confirmation of uterine hyperplasia for the coumestrol - treated animals . - pubmed
INTERVENTIONS : Empiric dosing for both groups was based on patient - specific pharmacokinetics and severity of infection . - pubmed
MEASUREMENTS AND MAIN RESULTS : Nephrotoxicity occurred in 7.5 % patients treated with ODA and 14.7 % receiving TDA ( p=0.05 ) . - pubmed
CONCLUSION : The trend was toward decreased nephrotoxicity in patients treated with ODA compared with TDA , and at any given cumulative AUC , the risk of toxicity was lower for ODA . - pubmed
Automated classification of human atrial fibrillation from intraatrial electrograms . - pubmed
Different ofloxacin - loaded unilamellar vesicles were prepared by the extrusion technique , and their antimicrobial activities were determined in comparison to those of the free drug by means of MIC determinations with both American Type Culture Collection standards and wild - type bacterial strains ( six strains of Enterococcus faecalis , seven strains of Escherichia coli , six strains of Staphylococcus aureus , and six strains of Pseudomonas aeruginosa ) . - pubmed
Relevant prevalence of Mycoplasma hominis and Ureaplasma urealyticum serogroups in HIV-1 infected men without urethritis symptoms . - pubmed
urealyticum are the better - known mycoplasma species pathogenic to the human genitourinary tract , causing mainly urethritis , bacterial vaginosis and pregnancy complications . - pubmed
The aim of this work was to determinate the prevalence of these species in this group of male patients ( HIV group ) , in comparison to a group of men with clinical symptoms of urethritis ( STD group ) . - pubmed
In the STD group these rates were 0.9 % ( 1/110 ) for M. - pubmed
A pneumococcal conjugate vaccine and acute otitis media . - pubmed
The effect of denervation or acute insulin deficiency on brown adipose tissue lipogenesis was investigated in rats adapted to a high - protein diet before and after diet reversion to a balanced diet . - pubmed
This review outlines the current state of knowledge of cerebral disease in humans , and discusses the contribution of studies of animal models to elucidation of the underlying mechanisms . - pubmed
Besides this difficulty in differentiation , a well - used medical school textbook of microbiology , Atlas , points out that even among experts , different observers may classify the same strain of bacteria as Nocardia or Mycobacterium tuberculosis . - pubmed
The therapeutic effect of PEPM - Cre plus CMV - lox - TK was also observed in xenografted LNCaP cells on nude mice when the plasmids were directly injected into tumors and GCV was administered intraperitoneally . - pubmed
Biopsy specimens were obtained from back skins treated with topical anthralin or white petrolatum ( control ) in 4 patients with psoriasis vulgaris . - pubmed
We report on the death of a 22 - year - old man after the ingestion of ecstasy pills containing PMMA and PMA . - pubmed
BACKGROUND : Patients with lipodermatosclerosis ( LDS ) due to chronic venous disease ( CVD ) of the lower limb show proliferation and convolution of their skin capillaries . - pubmed
Ten control subjects with no arterial or venous disease of the lower limb were also studied . - pubmed
In patients with skin changes the most severe regions of LDS were studied . - pubmed
CONCLUSIONS : Amongst patients with venous disease , capillary convolution is strongly associated with the more severe stages ( LDS and healed ulceration ) , which can reliably be reproduced by capillary microscope . - pubmed
BACKGROUND : Most reports on basilar artery ( BA ) occlusive disease have retrospectively described single cases or small patient series . - pubmed
OBJECTIVE : To assess clinical and vascular features , stroke mechanisms , etiologies , and outcome of moderate to severe BA occlusive disease among 407 patients in the New England Medical Center Posterior Circulation Registry , the largest prospective series of consecutively collected patients with posterior circulation ischemia to date . - pubmed
RESULTS : We studied 87 patients and identified 3 patient groups with distinct vascular , clinical , etiological , and prognostic characteristics : isolated BA disease ( 39 patients [ 44.8 % ] ) , BA involvement as part of widespread posterior circulation atherosclerosis ( 36 patients [ 41.4 % ] ) , and embolism to the BA ( 12 patients [ 13.8 % ] ) . - pubmed
Fifty - eight patients ( 66 % ) initially had transient ischemic attacks , of whom 34 ( 58.6 % ) progressed to stroke . - pubmed
Outcome was best among patients with widespread atherosclerotic disease and worst in 7 ; ( 58.3 % , with major disability ) of 12 patients with embolism to the BA . - pubmed
METHODS : Forty - four patients with advanced gastrointestinal cancer ( 25 gastric and 19 colorectal cancer ) and 25 healthy controls were enrolled . - pubmed
These changes may be correlated with hibernation arrest and death of treated jerboa . - pubmed
[ Establishment and judgement of the animal model of focal ischemia - reperfusion ] . - pubmed
OBJECTIVE : To investigate the influence of reperfusion after ischemia for 90 , 120 , 180 minutes on the focal ischemia reperfusion animal model . - pubmed
METHODS : The string - fastening method was used to establish focal ischemia - reperfusion models in SD rats and the rats were divided into 4 groups : ischemia - reperfusion for 90 , 120 and 180 minute groups and the sham operation group . - pubmed
CONCLUSION : Cerebral ischemia for 120 minutes is ideal for establishing the animal model . - pubmed
We have developed in vitro and in vivo animal models to study mechanisms of acquired peripheral neuropathies and used these models to evaluate the therapeutic potential of novel compounds . - pubmed
Subcutaneously implanted human A431 epidermoid carcinoma and U251 glioblastoma cells served as tumor models . - pubmed
Although tumor ( 18 ) F - FDG uptake was not above background activity under the reference condition , tumors demonstrated marked focal ( 18 ) F - FDG uptake in warmed and fasted animals . - pubmed
CONCLUSION : Animal handling has a dramatic effect on ( 18 ) F - FDG biodistribution and significantly influences the results of microPET studies in tumor - bearing mice . - pubmed
To improve tumor visualization mice should be fasted and warmed before ( 18 ) F - FDG injection and during the uptake period . - pubmed
Isoflurane appears well suited for anesthesia of tumor - bearing mice , whereas ketamine / xylazine should be used with caution , as it may induce marked hyperglycemia . - pubmed
METHODS : This was a retrospective , noninterventional case series of 11 patients with FES . - pubmed
Five patients had a known diagnosis of OSA . - pubmed
Pelibuey sheep ( 60 % , 6 of 10 ) ovulated continuously during the entire study ; one animal was eliminated in the second year , due to ovarian follicular cysts and three ewes had anestrous periods from 65+/-46 to 70+/-36 days . - pubmed
The body weight of Pelibuey ewes was constant during the entire study and was not correlated with ovulatory activity . - pubmed
A study to standardize quantitative evaluation of parotid gland scintigraphy in patients with Sjogren ' s syndrome . - pubmed
METHODS : Forty - five patients with SS and 23 controls were studied . - pubmed
RESULTS : The levels of peak count , uptake speed , and excretion speed in the patients with SS were significantly lower than the levels in the controls , whereas there was no significant difference of excretion fraction level between the patients with SS and the controls . - pubmed
Different effects of high molecular weight sodium hyaluronate and NSAID on the progression of the cartilage degeneration in rabbit OA model . - pubmed
OBJECTIVE : We examined the effects of nonsteroidal anti - inflammatory drug ( NSAID ) and intra - articular injections of sodium hyaluronate ( HA ) on cartilage degeneration in rabbit knee osteoarthritis ( OA ) model induced by partial meniscectomy . - pubmed
Breathing He / O2 can benefit critically ill patients with severe respiratory compromise mainly by reducing airway resistance in obstructive syndromes such as acute asthma and decompensated chronic obstructive pulmonary disease . - pubmed
The potential use of variola virus , the causative agent of smallpox , as a bioweapon and the endemic presence of monkeypox virus in Africa demonstrate the need for better therapies for orthopoxvirus infections . - pubmed
Correlation between radial artery tonometry- and fingertip tonometry - derived augmentation index in children with type 1 diabetes . - pubmed
Preparations containing isoflavones in variable doses , such as soy extract and red clover , or extracts from evening primrose , Cimifuga racemosa , ginseng and black cohosh are often used for treating the climacteric syndrome . - pubmed
Loss of penile length following penile implantation surgery is worrisome for patients suffering from erectile dysfunction ( ED ) . - pubmed
Infection by ToMV and feeding damage by H. - pubmed
Overall , this study indicated that , in general , insect damage has a stronger effect than ToMV infection on plant chemistry and , subsequently , on the performance of H. - pubmed
The predominant comorbidities were previous myocardial infarction in 71.4 % of the patients , diabetes mellitus in 34.2 % , and renal failure in 14.2 % . - pubmed
No cases of sternal dehiscence or infection were observed , but one patient suffered a stroke on the fourth postoperative day and died . - pubmed
No late deaths occurred , 31 patients are asymptomatic , and three have residual angina . - pubmed
A randomized Phase III study was started in Japan to demonstrate the non - inferiority of survival of accelerated fractionation radiation therapy ( 2.4 Gy / fr ) with conventional fractionation radiation therapy ( 2 Gy / fr ) in patients with T1 - 2N0M0 glottic cancer . - pubmed
METHODS : Thirty - two patients with parotid gland malignancy underwent tumor and parotid gland excision while preserving facial never . - pubmed
The patients were followed up after operation and the local tumor control and facial nerve function were observed . - pubmed
RESULTS : Tumor recurrence was not found in any patient treated after 12 to 44 months of follow up . - pubmed
We evaluated data from 390 patients ( 406 ankles ) who consulted our center because of painful end - stage ankle osteoarthritis ( OA ) by using medical history , physical examination , and radiography . - pubmed
Patients with posttraumatic end - stage ankle OA were younger than patients with primary OA . - pubmed
Cellular and molecular characterization of these cells revealed many similarities to human embryonic stem cells , and the germline stem cells produced teratomas after transplantation into immunodeficient mice . - pubmed
PATIENT(S ): Nineteen patients with PCOS and 21 controls . - pubmed
Nasal steroids helpful for short - term treatment of children with obstructive sleep apnea . - pubmed
In this paper , we present a series of 8 consecutive patients with diaphragmatic anomalies who underwent robotic repair . - pubmed
METHODS : We retrospectively reviewed patients with diaphragmatic anomalies . - pubmed
There were 2 patients with eventration , 5 with B - CDH , and 1 with M - CDH . - pubmed
CONCLUSIONS : Robotic surgery is safe and effective for repairing diaphragm anomalies in small children . - pubmed
Indications for the procedure were the evaluation of suspected inflammatory bowel disease in eight patients and evaluation of protein - losing enteropathy in one patient . - pubmed
We compared DNA damage and the efficacy of its repair after genotoxic treatment with gamma - radiation of lymphocytes and tissue cells isolated from patients with squamous cell carcinoma of head and neck ( HNSCC ) and healthy donors . - pubmed
We conclude that gamma - radiation might be considered as an effective therapeutic strategy for head and neck cancers , including patients in advanced stage of the disease with clear evidence of metastasis . - pubmed
Cord blood transplantation with a reduced - intensity conditioning regimen for patients with relapsed aggressive multiple myeloma after cytoreduction with bortezomib . - pubmed
Two multiple myeloma patients relapsed after autologous stem cell transplantation ( ASCT ) . - pubmed
The second patient developed acute and chronic GVHD , and both responded to the steroid therapy . - pubmed
As biochemical and molecular cobalt - induced toxicological mechanisms are not fully identified , we investigated cobalt toxicity in a model human keratinocyte cell line , HaCaT. - pubmed
Genetic counseling and risk assessment depend on determination of the specific cause of an inherited ataxia in an individual . - pubmed
RESULTS : Of the 582 included women , 76 developed ESRD 3.9 + - 3.4 years ( range , 0.08 - 16 years ) after diagnosis . - pubmed
Here , we report our experience on three patients with AMR who were treated with bortezomib after other therapeutic interventions had failed . - pubmed
The third patient developed worsening thrombocytopenia following the second dose . - pubmed
CLINICAL PRESENTATION : Two patients , age 44 and 60 years , presented with Hunt and Hess grade 3 subarachnoid hemorrhage from aneurysmal rupture . - pubmed
A double - blind , placebo - controlled comparison of letrozole to oxandrolone effects upon growth and puberty of children with constitutional delay of puberty and idiopathic short stature . - pubmed
METHODS : In a prospective , double - blind , randomized , placebo - controlled clinical trial , 91 CDGP boys ( 12.6 - 14.6 years old ) with predicted short stature were treated with letrozole ( 2.5 mg / day ) , oxandrolone ( 2.5 mg / day ) , or placebo , at the outpatient pediatric endocrine clinic of Mofid Children 's Hospital in Tehran for 2 years . - pubmed
CONCLUSION : This first randomized controlled clinical trial in CDGD teenage boys with predicted short stature shows that letrozole increases PAH more than oxandrolone and advances pubertal stage and bone mineralization less . - pubmed
METHODS : The BSR cell was infected by triple serial dilution of the Rabies Virus CTN strain , then detect the fluorescent focus by FITC labeling anti - Rabies Virus monoclonal antibodies . - pubmed
ABSTRACT : Synaptic dysfunction is widely thought to be a pathogenic precursor to neurodegeneration in Alzheimer ' s disease ( AD ) , and the extent of synaptic loss provides the best correlate for the severity of dementia in AD patients . - pubmed
Influence of 5 - HTTLPR polymorphism on resting state perfusion in patients with major depression . - pubmed
MDD patients were stratified according to receptor polymorphism , both using a bi - allelic ( group A : L / L vs. group B : S / S and S / L genotype ) and a tri - allelic approach ( Group A ' : LA / LA vs. Group B ' : non - LA / LA genotype ) . - pubmed
We demonstrate that in patients with MDD , 5 - HTTLPR gene polymorphism modulates resting state perfusion in key structures of mood processing . - pubmed
Collagen - induced arthritis in common marmosets : a new nonhuman primate model for chronic arthritis . - pubmed
INTRODUCTION : There is an ever - increasing need for animal models to evaluate efficacy and safety of new therapeutics in the field of rheumatoid arthritis ( RA ) . - pubmed
In response to this requirement we set out to develop a model of collagen - induced arthritis ( CIA ) in a small - sized nonhuman primate species ( 300 to 400 g at adult age ) ; that is , the common marmoset ( Callithrix jacchus ) . - pubmed
RESULTS : Clinically manifest arthritis was observed in almost 100 % ( 21 out of 22 ) of the animals . - pubmed
Fifty percent of the animals developed semi - acute CIA while the other 50 % displayed a more chronic disease . - pubmed
CONCLUSIONS : This new model in marmosets more closely resembles chronic RA with respect to the chronic disease course and pathomorphological presentation than the more acute monophasic and destructive CIA model in macaques . - pubmed
Differential mucosal expression of Th17 - related genes between the inflamed colon and ileum of patients with inflammatory bowel disease . - pubmed
In the present study , the cytotoxic effect of a new flavonoid , 2 -( cis-1 , 2 - dihydroxy 4 - oxo - cyclohex-5 - enyl )- 5 , 7 - dihydroxy - chromone ( DEDC ) , which is a protoapigenone analog , was investigated in human hepatoma HepG2 cells . - pubmed
Feasibility study of the zebrafish assay as an alternative method to screen for developmental toxicity and embryotoxicity using a training set of 27 compounds . - pubmed
To anticipate to increased testing needs for reproductive toxicity and 3R approaches , we studied zebrafish embryo / larva as an alternative for animal testing for developmental toxicity and embryotoxicity and evaluated a training set of 27 compounds with a standardized protocol . - pubmed
Efficacy of second - generation antihistamines in patients with allergic rhinitis and comorbid asthma . - pubmed
Clinical trials were included that reported results for patients with AR and comorbid asthma who were treated with second - generation antihistamines . - pubmed
Mechanistic and clinical data suggest that the potential of H1 - antihistamines to alleviate comorbid asthma symptoms in AR patients should be further investigated . - pubmed
Diphtheria , pertussis ( whooping cough ) , and tetanus vaccine induced recurrent seizures and acute encephalopathy in a pediatric patient : Possibly due to pertussis fraction . - pubmed
Recommendations for management of patients with carotid stenosis . - pubmed
This paper will highlight the complexities of decision - making optimal treatment recommendations for patients with symptomatic and asymptomatic carotid stenosis . - pubmed
This is the first reported case in which parotid tumour was the presenting complaint of the patient . - pubmed
Thirty - nine RCC patients were selected for 3 - year disease - free survival analysis . - pubmed
Patients had been classified at baseline as tremordominant or akinetic - rigid according to a " tremor score " and " non - tremor score " . - pubmed
At follow - up , akinetic - rigid patients showed a distinct and statistically significant reduction of the dopaminergic uptake associated with significant progression of the clinical symptoms ( UPDRS III ) . - pubmed
In contrast , in tremor patients the aggravation of clinical symptoms and dopaminergic deficit was less pronounced without statistical significance among assessments . - pubmed
CONCLUSIONS : This study shows for the first time a considerable progression of clinical symptoms and in - vivo dopaminergic deficit of akinetic - rigid compared to tremordominant PD patients over time . - pubmed
Multislice computed tomography to rule out coronary allograft vasculopathy in heart transplant patients . - pubmed
BACKGROUND : This study assessed if invasive coronary angiogram ( CA ) could be replaced by multislice ( 64- or 256 - row ) computed tomography ( MSCT ) to systematically rule out coronary allograft vasculopathy in heart transplant patients . - pubmed
CONCLUSION : Newer generations of MSCT ( 64- or 256 - row ) have a good NPV and may represent an alternative to invasive CA to rule out significant ( & gt;50 % ) coronary vasculopathy in heart transplant patients , despite a low PPV . - pubmed
In 60 % of the patients , this congenital lesion presents bilaterally . - pubmed
As IHAE scientists assessed human performance and adaptation to hypoxia , low barometric pressure , and cold , they not only illuminated the physiological and psychological processes of high altitude acclimatization , but they also drew borderlines between the normal and the pathological , paved the way for the neocolonial exploitation of natural and human resources in Latin America , and pioneered field methods in physiology that were adapted and adopted by the Allied Forces during the Second World War . - pubmed
BACKGROUND AND PURPOSE : Despite appropriate radiotherapy , high - risk prostate cancer patients often experience local relapse and progression to metastatic disease . - pubmed
In vivo , BEZ235 pretreatment enhanced the efficacy of radiation therapy on PC3 xenograft tumors in mice without inducing intestinal radiotoxicity . - pubmed
Drug screening using a library of human induced pluripotent stem cell - derived cardiomyocytes reveals disease - specific patterns of cardiotoxicity . - pubmed
BACKGROUND : Cardiotoxicity is a leading cause for drug attrition during pharmaceutical development and has resulted in numerous preventable patient deaths . - pubmed
Here we generated a library of human induced pluripotent stem cell - derived cardiomyocytes ( hiPSC - CMs ) from patients with various hereditary cardiac disorders to model differences in cardiac drug toxicity susceptibility for patients of different genetic backgrounds . - pubmed
METHODS AND RESULTS : Action potential duration and drug - induced arrhythmia were measured at the single cell level in hiPSC - CMs derived from healthy subjects and patients with hereditary long QT syndrome , familial hypertrophic cardiomyopathy , and familial dilated cardiomyopathy . - pubmed
CONCLUSIONS : We have recapitulated drug - induced cardiotoxicity profiles for healthy subjects , long QT syndrome , hypertrophic cardiomyopathy , and dilated cardiomyopathy patients at the single cell level for the first time . - pubmed
Our data indicate that healthy and diseased individuals exhibit different susceptibilities to cardiotoxic drugs and that use of disease - specific hiPSC - CMs may predict adverse drug responses more accurately than the standard human ether - a - go - go - related gene test or healthy control hiPSC - CM / hESC - CM screening assays . - pubmed
Self - correction of chromosomal abnormalities in human preimplantation embryos and embryonic stem cells . - pubmed
This review addresses aneuploidies in human preimplantation embryos and human ESCs and the potential of self - correction of these aberrations . - pubmed
OBJECTIVE : To describe the behavior and characteristics of GERD in patients with recurrent laryngitis . - pubmed
MATERIAL AND METHODS : This is a retrospective study involving pediatric patients with recurrent laryngitis ( 2 or more episodes in 6 months ) referred for study of possible GERD . - pubmed
CONCLUSION : There is a significant percentage of patients with normal 24 hour Ph monitoring that had not been diagnosed with GERD without IIM . - pubmed
OBJECTIVE : The aim of this study was to analyze and compare the clinicopathologic characteristics , treatment , and survival in patients with uterine leiomyosarcoma ( ULMS ) during the last 10 years in 3 referral academic centers . - pubmed
METHODS : All patients with ULMS who underwent treatment at the participating institutions between January 1 , 2000 , and December 31 , 2010 , were identified from the tumor registry database . - pubmed
RESULTS : Analysis of 167 women with ULMS with adequate follow - up was performed . - pubmed
Metformin for weight loss and metabolic control in overweight outpatients with schizophrenia and schizoaffective disorder . - pubmed
OBJECTIVE : The purpose of this study was to determine whether metformin promotes weight loss in overweight outpatients with chronic schizophrenia or schizoaffective disorder . - pubmed
METHOD : In a double - blind study , 148 clinically stable , overweight ( body mass index [ BMI ] & gt;=27 ) outpatients with chronic schizophrenia or schizoaffective disorder were randomly assigned to receive 16 weeks of metformin or placebo . - pubmed
CONCLUSIONS : Metformin was modestly effective in reducing weight and other risk factors for cardiovascular disease in clinically stable , overweight outpatients with chronic schizophrenia or schizoaffective disorder over 16 weeks . - pubmed
Metformin may have an important role in diminishing the adverse consequences of obesity and metabolic impairments in patients with schizophrenia . - pubmed
Surgical management of patients with bowel obstructions secondary to gastric cancer . - pubmed
METHODS : The medical records of all of the patients who were admitted for an intestinal obstruction after curative resection for gastric cancer were retrospectively reviewed . - pubmed
The patients were divided into 2 groups : patients with no evidence of a tumor recurrence and patients with evidence of a tumor recurrence . - pubmed
Open and close surgery was the main type of surgical procedure reported for the patients with tumor recurrences . - pubmed
The consequence of strawberries coating , with antifungal composite based solution , was the disappearance of gray mold infection signs in 90 % of the contaminated fruits after 7 d of storage , treated fruits had a fresh - like appearance at the end of storage . - pubmed
Use of 111In - pentetreotide scan in a subject with treatment refractory atypical meningioma . - pubmed
The patient remained symptomatic with intermittent severe headaches associated with nausea , vomiting , and visual disturbance . - pubmed
Univariate and multivariate random effects negative binomial regressions were used to predict risk factors for child malaria incidence and the mean total number of indoor female Anopheles gambiae and funestus mosquitoes collected per household across three occasions . - pubmed
Multivariate regressions showed that residing in rural areas ( versus urban ) increased malaria incidence rates by over three - fold and mean indoor female A. - pubmed
Ischemia - reperfusion is a major determinant of myocardial impairment in patients undergoing cardiac surgery . - pubmed
First described in animals in 1986 , myocardial ischemic conditioning consists of applying increased tolerance of the myocardium to sustained ischemia by exposing it to brief episodes of ischemia - reperfusion . - pubmed
Tongue diagnosis system for quantitative assessment of tongue coating in patients with functional dyspepsia : a clinical trial . - pubmed
MATERIALS AND METHODS : The present study was designed as a prospective clinical trial including 60 patients with functional dyspepsia . - pubmed
Here we describe the design of GIFM experiments in adult mice as exemplified by CreER(T2)-assisted tracing of vascular smooth muscle cells during the development of atherosclerotic lesions . - pubmed
Recurrent hospital admission rates with exacerbation of obstructive pulmonary disease were higher in the illicit drug smokers compared with current / ex - tobacco smokers ( 1.00 versus 0.22/0.26 , p & lt ; 0.001 ) . - pubmed
Many strategies have been evaluated over the past 15 years but none of these approaches has resulted in improved survival rates for patients with SCLC . - pubmed
Specifically , the article discusses ganitumab and its applicability to SCLC patients . - pubmed
EXPERT OPINION : At present , there is a lack of therapeutic choices for patients with advanced SCLC . - pubmed
Unfortunately , ganitumab , administered in combination with chemotherapy , demonstrated no clinical activity in patients with SCLC , although it could have utility with other cancers . - pubmed
Fungal melanonychia caused by Trichophyton rubrum and the value of dermoscopy . - pubmed
METHODS : In a prospective and multicenter study , children with suspected peanut or hazelnut allergy underwent oral challenges . - pubmed
RESULTS : Among 563 screened patients , 75 ( 13.3 % ) were Her2 positive ( IHC 2+/3 + and FISH+ ) and 61 met all eligibility criteria ( median age , 64 years ; 54/61 males ; 50/61 baseline ECOG - PS 0 - 1 ; 11 locally advanced and 50 metastatic ) . - pubmed
These data indicate that multiple mechanisms contribute to the rare , but potentially severe liver injury caused by sitaxentan in humans ; provide a plausible rationale for the markedly lower propensity of bosentan to cause liver injury ; and highlight the relative safety of ambrisentan . - pubmed
The tsetse fly vector transmits the protozoan Trypanosoma brucei , responsible for Human African Trypanosomiasis , one of the most neglected tropical diseases . - pubmed
Patients presenting with nephritic syndrome tend to be hypertensive with dipstick - positive or visible haematuria . - pubmed
All patients with glomerulonephritis should be managed according to CKD guidelines with CKD stage - appropriate measurement of renal function , blood pressure , and proteinuria . - pubmed
Six patients had scapholunate joint widening , one had windshield - wipering of the screws with loss of reduction , and two demonstrated progression of scapholunate advanced collapse deformity . - pubmed
Patients who underwent elective operations that involved long wound closure were enrolled in the study . - pubmed
Each patient acted as their own internal control with half their wound being sutured with 3/0 V - Loc 180 barbed suture and the other half with smooth 3/0 Maxon deep dermal sutures and then a subcuticular skin closure . - pubmed
RESULTS : The false - positive rate for AA among 413 VLBW infants was significantly higher than infants with birth weight & gt;1500 g ( 7.62 % vs 0.05 % ; P & lt ; .001 ) . - pubmed
METHODS : In total , 102 consecutive patients with hip fracture over the age of 65 were admitted to the orthopedic unit and prospectively evaluated . - pubmed
All of the patients were treated according to specific protocols depending on the type of fracture . - pubmed
Among these patients , 73 % were female , and 37 % had vitamin D deficiency . - pubmed
The median LOS was 7 ( 5 - 11 ) d. Patients with vitamin D deficiency had lower handgrip strength in univariate analysis . - pubmed
RESULTS : In the time period , 1939 children were hospitalized due to varicella infection in Turkey ; 36 children ( 20 boys , 16 girls , mean age 68.0 + 37.6 months , all received single dose live varicella vaccine ) with breakthrough varicella infection . - pubmed
METHODS : We retrospectively reviewed the clinical and pathological files of patients having undergone EBUS - TBNA from February 2011 to October 2014 to investigate thoracic lesions . - pubmed
Among 736 patients , we identified four of them with a diagnosis of MPM achieved primarily through EBUS - TBNA . - pubmed
RESULTS : In all patients , the collected tissue was adequate , and the histological analysis in association with immunohistochemistry led us to the diagnosis of malignant pleural mesothelioma . - pubmed
In three patients , the diagnosis of mesothelioma was clinically suspected , as patients presented with diffuse pleural thickening . - pubmed
In two patients , videothoracoscopy was not possible owing to the ' dry ' presentation of the pleural disease and the site of thickening . - pubmed
OBJECTIVE : Transcatheter aortic valve implantation ( TAVI ) is an alternative treatment for patients with severe symptomatic aortic stenosis , inoperable or at high surgical risk . - pubmed
METHODS : Review of 17 patients data with symptomatic severe aortic stenosis at high surgical risk or inoperable , treated with a transcatheter implantation aortic valve ( TAVI ) via femoral surgical access with Core Valve ( Medtronic , EE.UU . ) - pubmed
RESULTS : All patients had severe aortic stenosis with a mean gradient of 46ae14 mmHg received CoreValveTM ( Medtronic , USA ) . - pubmed
One patient complicated with acute renal failure , 2 had in - hospital ischemic stroke ( 11.7 % ) , none had need for cardiac surgery ; 2 patients had major bleeding complications that required transfusion . - pubmed
We provide a perspective on our experience with human and murine Treg suppression assay conditions , including Treg data obtained in clinical transplant studies , Tregs isolated from healthy donors and treated with epigenetically active compounds , and Tregs from standard murine strains ( C57BL/6 and BALB / c ) . - pubmed
The patient had microvascular complications of diabetes . - pubmed
Precise targeting of genetic lesions alone has been insufficient to extend brain tumor patient survival . - pubmed
RESULTS A total of 133 lasers were placed in 102 patients who required intervention for intracranial tumors ( 87 patients ) , chronic pain syndrome ( cingulotomy , 5 patients ) , or epilepsy ( 10 patients ) . - pubmed
Ninety - two patients ( 90.2 % ) had undergone previous treatment for their intracranial tumors . - pubmed
For some members of this group , antiviral activity was also found against human cytomegalovirus , hepatitis B , norovirus , and measles . - pubmed
The purpose of this study is to demonstrate , using multivariate analysis of preoperative and intraoperative patient characteristics to determine risk factors for negative outcomes , that PD can be performed safely in the elderly . - pubmed
RESULTS : Death occurred in one patient ( 2.3 % ) in group A. - pubmed
BACKGROUND AND AIMS : Although endoscopic ultrasound ( EUS ) is used in the management of various gastrointestinal ( GI ) diseases in adults , data on its role in children is limited . - pubmed
EUS diagnosed chronic pancreatitis ( 21 patients ) , pancreatic necrosis ( 1 ) , splenic artery pseudoaneurysm ( 1 ) , gastric varix ( 1 ) , pseudocysts ( 3 ) , insulinomas ( 2 ) , other pancreatic masses ( 2 ) , choledocholithiasis ( 2 ) , choledochal cysts ( 2 ) , portal biliopathy ( 1 ) , esophageal leiomyoma ( 1 ) , gastric neuroendocrine tumor ( NET ) ( 1 ) , and GI stromal tumor in stomach ( 1 ) . - pubmed
EUS - guided FNAC was positive in four of seven patients ( two had tuberculosis , one pancreatic solid pseudopapillary tumor , and one gastric NET ) . - pubmed
MATERIAL AND METHODS : Forty - five patients with chronic periodontitis and 45 periodontally healthy patients were included in this case - control study . - pubmed
We report a case of a 60 - year - old man diagnosed with papillary thyroid cancer who had a relapse seen only in the brain at FDG PET on standard images . - pubmed
Perfusion cardiovascular magnetic resonance and fractional flow reserve in patients with angiographic multi - vessel coronary artery disease . - pubmed
METHODS AND RESULTS : Forty - one patients ( 123 vascular territories ) with angiographic 2- or 3 - vessel coronary artery disease ( visual stenosis & gt;50 % ) underwent high - resolution adenosine stress perfusion CMR at 1.5 T and FFR measurement . - pubmed
Validation and optimization of a predictive model for radiation pneumonitis in patients with lung cancer . - pubmed
Consecutive patients with non - small cell lung carcinoma ( NSCLC ; n=71 ) treated with definitive concurrent chemotherapy and radiotherapy were retrospectively assessed for radiation pneumonitis ( RP ) . - pubmed
The Effectiveness of Mental Practice : With Motor Imagery in the Neurological Rehabilitation of Stroke Patients * for the improvement of UE function . - pubmed
STUDY DESIGN AND OBJECTIVES : This study by Srikandarajah et al is a retrospective cohort study of 200 CES patients . - pubmed
Srikandarajah et al concluded that in CESI patients , decompressive surgery within 24 hours of onset of autonomic symptoms reduces bladder dysfunction at follow - up . - pubmed
[ Preoperative , neuropathic component in patients with back pain ] . - pubmed
OBJECTIVE : The goal of the study was the preoperative screening of a neuropathic component in patients with vertebral compression fracture ( WKF ) , herniated disc ( NPP ) or spinal cord compression ( SKS ) . - pubmed
CONCLUSION : The painDETECT questionnaire was shown to be a very suitable instrument for evaluating the neuropathic pain component in patients with dorsalgia . - pubmed
Incidence of post - anesthetic colic in non - fasted adult equine patients . - pubmed
The purpose of this study was to determine the incidence of post - anesthetic colic in non - fasted adult horses undergoing isoflurane inhalant anesthesia for an elective , non - abdominal procedure at a single referral center . - pubmed
INNOVATION Study ( Impact of Immediate Stent Implantation Versus Deferred Stent Implantation on Infarct Size and Microvascular Perfusion in Patients With ST - Segment - Elevation Myocardial Infarction ) . - pubmed
A 65 - year - old man presented with diarrhea and abdominal pain . - pubmed
Changes in gastric smooth muscle cells of diabetic rats with induced gastroparesis were examined . - pubmed
The diabetic rat model was established by dividing animals into a normal control group and diabetic model groups examined at 2 , 4 and 6 weeks . - pubmed
Contribution of Genetic Factors to Lower DHEAS in Patients with Rheumatoid Arthritis . - pubmed
METHODS : Surgical specimens from seven hepatocellular carcinoma patients with portal vein thrombosis and seven patients without vascular invasion were utilized to analyze protein expression by proteomic technique . - pubmed
The median survival time for the patients with portal vein thrombosis was much shorter [ 4 ( ranged 2.5 - 47 ) vs. 53 ( ranged 33 - 85 ) months , p = 0.002 ] . - pubmed
Serum urate levels are reported to be significantly lowered in patients with Parkinson ' s disease ( PD ) and inversely correlated to the risk and progression of PD . - pubmed
METHODS : In this randomised , double - blind , phase 3 trial , we recruited patients aged 18 years and older with glioblastoma from 165 hospitals in 22 countries . - pubmed
FINDINGS : Between April 12 , 2012 , and Dec 15 , 2014 , 745 patients were enrolled ( 405 with MRD , 338 with significant residual disease [ SRD ] , and two unevaluable ) and randomly assigned to rindopepimut and temozolomide ( n=371 ) or control and temozolomide ( n=374 ) . - pubmed
The most common grade 3 - 4 adverse events for all 369 treated patients in the rindopepimut group versus 372 treated patients in the control group were : thrombocytopenia ( 32 [ 9 % ] vs 23 [ 6 % ] ) , fatigue ( six [ 2 % ] vs 19 [ 5 % ] ) , brain oedema ( eight [ 2 % ] vs 11 [ 3 % ] ) , seizure ( nine [ 2 % ] vs eight [ 2 % ] ) , and headache ( six [ 2 % ] vs ten [ 3 % ] ) . - pubmed
16 deaths in the study were caused by adverse events ( nine [ 4 % ] in the rindopepimut group and seven [ 3 % ] in the control group ) , of which one - a pulmonary embolism in a 64 - year - old male patient after 11 months of treatment - was assessed as potentially related to rindopepimut . - pubmed
INTERPRETATION : Rindopepimut did not increase survival in patients with newly diagnosed glioblastoma . - pubmed
We randomized 126 hypertensive patients on hemodialysis to a standardized predialysis systolic BP of 110 - 140 mmHg ( intensive arm ) or 155 - 165 mmHg ( standard arm ) . - pubmed
Most VNS research in the treatment of inflammation have been acute studies on rodent subjects . - pubmed
SUMMARY : The patient is a 56 - year - old man who presented dysphagia for solids and liquids , snoring ( score 10 ) and excessive daytime sleepiness for 5 years . - pubmed
DISCUSSIONS : This is the first reported case of Forestier Syndrome ( FS ) associated with Obstructive Sleep Apnea ( OSA ) that was proposed surgical treatment and the patient evolved with complete symptom improvement . - pubmed
Effectiveness of prowling with proprioceptive training on knee hyperextension among stroke subjects using videographic observation- a randomised controlled trial . - pubmed
RESULTS : A total of 56 hypertensive events were evaluated in 30 patients . - pubmed
Impairments of postural control , functional performance and strength in morbidly obese patients awaiting bariatric surgery in comparison to healthy individuals . - pubmed
Resistance to gastrointestinal nematodes in dairy sheep : Genetic variability and relevance of artificial infection of nucleus rams to select for resistant ewes on farms . - pubmed
The alteration of microRNA ( miR)-130b expression has been associated with promoting or suppressing numerous types of human cancer . - pubmed
Tafenoquine receives regulatory approval in USA for prophylaxis of malaria and radical cure of Plasmodium vivax . - pubmed
However , it has been reported to be associated with a lower risk of adverse events in patients with cancer or acute coronary syndrome . - pubmed
Results The unadjusted population included 1,536 HC patients and 330 non - HC patients . - pubmed
After baseline adjustment , the outcomes of HC patients were significantly better than those of the non - HC patients with respect to the primary endpoint , which was a combination of mortality from all causes , nonfatal myocardial infarction ( MI ) , nonfatal neurological events , and major bleeding [ hazard ratio ( HR ) 0.56 , 95 % confidence interval ( CI ) 0.39 - 0.81 ; p=0.002 ] , and the secondary endpoints , which included a combination of mortality from all causes , nonfatal MI , and nonfatal neurological events ( HR 0.59 , 95 % CI 0.39 - 0.88 ; p=0.01 ) , and major bleeding ( HR 0.42 , 95 % CI 0.20 - 0.88 ; p=0.02 ) . - pubmed
Virtual touch IQ elastography in evaluation of Achilles tendon in patients with chronic renal failure . - pubmed
PURPOSE : To evaluate the sonoelastographic changes in the Achilles tendon in patients with chronic renal failure ( CRF ) using virtual touch imaging quantification ( VTIQ ) elastography . - pubmed
RESULTS : The median values of shear wave velocities of the Achilles tendon in patients with CRF were 7.19 m / s ( 4.23 - 9.77 m / s ) on the right and 6.98 m / s ( 4.00 - 9.82 m / s ) on the left , while they were 5.11 m / s ( 4.09 - 8.82 m / s ) on the right and 5.36 m / s ( 4.05 - 8.80 m / s ) on the left in controls . - pubmed
The stiffness of the Achilles tendons in patients with CRF was found to be higher than that in controls ( right : P & lt ; 0.001 , left : P = 0.004 ) . - pubmed
The thickness of the Achilles tendon did not significantly differ between the patients with CRF and healthy subjects . - pubmed
However , the stiffness of the Achilles tendon measured with VTIQ elastography was demonstrated to be increased in the patients with CRF . - pubmed
Upon irradiation with near - infrared light , they caused rapid tumor shrinkage and significantly prolonged the survival of tumor - bearing mice . - pubmed
Long - term functional outcomes and quality of life in patients with Hirschsprung ' s disease . - pubmed
The aim of this cross - sectional study was to determine the long - term functional outcomes and quality of life ( QoL ) in patients with Hirschsprung ' s disease . - pubmed
METHODS : Patients with pathologically proven Hirschsprung ' s disease older than 7 years were included . - pubmed
METHODS : Tissue arrays were made from 135 paraffin - embedded ESCC samples and examined for histone markers by immunohistochemistry , and 10 pairs of cancer and noncancerous mucosa tissues from ESCC patients were investigated with Western blot . - pubmed
Conclusions : Copanlisib provides an alternative option for patients with relapsed FL . - pubmed
Early surgical intervention for patients with possible clinically silent somatotroph adenoma : a case series . - pubmed
CONCLUSION : Due to its potential for evolving to symptomatic disease , the risks of surgery and observation for patients with somatotroph adenoma should be carefully compared from the viewpoint of better health outcome . - pubmed
METHODS : In a double - blind multicenter trial , patients with Kawasaki disease received either etanercept ( 0.8 mg / kg ; n = 100 ) or placebo ( n = 101 ) subcutaneously starting immediately after IVIg infusion . - pubmed
RESULTS : Of 318 058 patients with localized prostate cancer ( PCa ) , 55 566 ( 18.4 % ) underwent BT . - pubmed
After propensity score - matching , 20 - year secondary BCa incidence was 6.0 % in patients who had undergone BT vs 2.4 % in those who had undergone RP ( P & lt ; 0.001 ) and the respective 20 - year secondary RCa incidence was 1.1 % vs 0.5 % ( P & lt ; 0.001 ) . - pubmed
Renal interstitial lymphangiogenesis is found in patients with chronic kidney disease ( CKD ) and a series of animal models of renal fibrosis . - pubmed
A Retrospective Review of Angiotensin II Use in Adult Patients With Refractory Distributive Shock . - pubmed
RESULTS : A total of 16 patients received ATII for distributive shock . - pubmed
No patients developed thrombotic or infectious complications after receiving ATII . - pubmed
A total of 223 adults with class III obesity aged 41.20 + - 10.15 years were included . - pubmed
Continued exposure of anti - cancer drugs to human iPS cell - derived cardiomyocytes can unmask their cardiotoxic effects . - pubmed
To develop a sensitive assay system for cardiotoxicity , we examined effects of anti - cancer drugs on contractile functions of human iPS cell - derived cardiomyocytes by using non - invasive motion field imaging analysis with extended drug exposure time . - pubmed
A novel mortality risk score predicting intensive care mortality in cardiogenic shock patients treated with veno - arterial extracorporeal membrane oxygenation . - pubmed
PURPOSE : Mortality after veno - arterial extracorporeal membrane oxygenation ( VA - ECMO ) implantation remains a major problem in patients with cardiogenic shock . - pubmed
Materials and Methods : We examined if there existed sensory - motor dysfunction in UB of aging mice . - pubmed
METHODS : A total of 15 patients with periocular aging underwent monthly treatment sessions of 3DEEP and FSR for three months . - pubmed
The primary aim of this study is to compare the effects of two , 6 - month physical activity programs on quality of life in patients with fibromyalgia . - pubmed
CONCLUSION : The risk of underlying high - grade cervical lesions in women with ASC - US on cervical cytology was approximately 5 % , regardless of HIV status . - pubmed
Also , no increase was seen in the kidneys of non - diabetic rats with body weight similar to that of the diabetics . - pubmed
The content and composition of phospholipids were studied in the brain of children who died from severe malnutrition within the first 2 years of life , and compared with those obtained from well - nourished children who died of accidents , or of illnesses not known to affect the central nervous system . - pubmed
With the exception of a few marasmic children under 1 year of age whose forebrain and cerebellum had higher phospholipid concentration than normal , the concentration of the lipids on dry weight basis in all brain regions of the malnourished children was the same , regardless of age , as that in the children who were normal nutritionally . - pubmed
Protein metabolism in rats with ventromedial hypothalamic lesions : dietary effects on nitrogen retention . - pubmed
Latency in vitro of varicella - zoster virus in cells derived from human fetal dorsal root ganglia . - pubmed
A potential in vitro model of varicella - zoster virus ( VZV ) latency was developed . - pubmed
Dissociated human dorsal root ganglion cultures were infected with VZV and maintained for 1 wk in the presence of bromovinyl arabinosyl uracil , a potent inhibitor of VZV . - pubmed
VZV reactivated from 56 % of the cultures containing both neurons and satellite cells but not from cultures specifically enriched for either neurons , satellite cells , or ganglion - derived fibroblasts . - pubmed
These findings suggest that cultures containing both neurons and satellite cells provide a model system for VZV persistence that possesses many properties of a latent infection . - pubmed
IgA B lymphocytes and subpopulations of T lymphocytes in the intestinal villi of immunodeficient Wistar rats . - pubmed
The clinical importance of these arrhythmias in humans is still a matter of debate . - pubmed
This finding is consistent with the location of the mouse twitcher mutation ( a model of human GALC deficiency ) on chromosome 12 , which has substantial homology to human chromosome 14 . - pubmed
Twenty patients underwent bilateral sagittal ramus osteotomy for the correction of mandibular retrognathia . - pubmed
Nuclear magnetic resonance studies of blood plasma and urine from subjects with chronic renal failure : identification of trimethylamine - N - oxide . - pubmed
We have used 1H- , 13C- and 14N - NMR spectroscopy to investigate the constituents of plasma and urine in 16 patients with chronic renal failure ( CRF ) . - pubmed
For the first time in the microcorrosion study of the nasal vascular network human fetuses ( from the 12th to 24th week of intrauterine life ) obtained from spontaneous abortions were used as well as rats weighing from 250 to 300 gr . - pubmed
Cells isolated from patients were positive in expression except for cells from acute myeloblastic leukemia with maturation ( AML M2 ) , acute hypergranular promyelocytic leukemia ( AML M3 ) and erythroleukemia ( AML M6 ) developed from myelodysplastic syndromes . - pubmed
Gastric rupture in horses : 50 cases ( 1979 - 1987 ) . - pubmed
A computer - based search was conducted of medical and necropsy records of horses admitted to the teaching hospital from Jan 1 , 1979 , to Dec 31 , 1987 , to obtain the records of all horses admitted to the hospital for colic and subsequently found to have gastric rupture . - pubmed
The results indicated that horses on a diet of grass hay or grass / alfalfa hay only or those that drank water from a bucket , stream , or pond were at increased risk for having gastric rupture . - pubmed
We present a rational approach to the workup and treatment of patients with head and neck cancer and a pulmonary nodule on chest radiography . - pubmed
to renal hypertensive mongrel dogs caused decreases in systolic blood pressure which persisted for 3 h. Mild salivation and hyperventilation were observed with both doses . - pubmed
34 patients with myocardial hypertrophy , mean age 44 years , were examined by two - dimensional echocardiography and the degree of disproportion of the hypertrophy of the different left ventricular segments was analyzed . - pubmed
The three sequential inactivation treatments used in manufacture of the vaccine kill hepatitis B virus and other infectious agents that may be present in human plasma , including the human T cell - lymphotropic virus that causes the acquired immunodeficiency syndrome . - pubmed
[ Calcified thrombosis of the inferior vena cava in children ] . - pubmed
We reviewed the records of 2,400 consecutive patients undergoing cardiac catheterization at USAF Medical Center Keesler between 1978 and 1984 and found 35 patients ( 1.5 percent of all cardiac catheterizations ) aged 35 years or less ( mean age , 32 years ) who underwent cardiac catheterization after myocardial infarction . - pubmed
These 35 patients ( group 1 ) were compared to a randomly selected group of 100 patients ( group 2 ) aged 55 years or greater who underwent cardiac catheterization for evaluation of coronary artery disease during the same period . - pubmed
Canine hemangiopericytoma : 23 cases ( 1967 - 1984 ) . - pubmed
The medical records of 23 histopathologically confirmed cases of canine hemangiopericytoma were reviewed . - pubmed
[ Iatrogenic bronchial obstruction : study of 4 atopic children with bronchial obstruction induced by acetyl salicylic acid ] . - pubmed
The authors have studied the modification of the spirometric parameters in four atopic children , during nonallergic diet , after administration of ASA ( 400 mg ) . - pubmed
When cells of each of these species are examined directly in infected tissue in the rabbit tibia model infection , their cell wall thickness is often much increased and very irregular around the circumference of the cell , their cell size is often increased , and their septation patterns are often severely deranged . - pubmed
Apart from one exception , there has been no reference to the possible causation of large liver abscesses by M. - pubmed
Comparison of resuscitation of sheep and dogs after bupivacaine - induced cardiovascular collapse . - pubmed
While the bupivacaine was given , the animals were made apneic for 90 sec and then ventilated with 100 % oxygen . - pubmed
After the bupivacaine administration , cardiovascular collapse occurred in the form of electromechanical dissociation progressing to asystole in dogs , whereas in sheep the predominant rhythm was ventricular fibrillation leading to asystole . - pubmed
The initial dose of bupivacaine used to cause cardiovascular collapse was 3.5 + /- 1.2 mg / kg in sheep and 24.6 + /- 8.5 mg / kg in dogs ( P less than 0.01 ) . - pubmed
All sheep and dogs were resuscitated from the first cardiovascular collapse . - pubmed
All dogs could be resuscitated after two additional cardiovascular collapses induced by bupivacaine , but no sheep could be resuscitated after a second cardiovascular collapse . - pubmed
Three patients were transplanted with the antibody - treated bone marrow cells during the first remission period after preconditioning with intensive chemotherapy and total body irradiation , while transplantations in two other patients , who were in poor clinical condition , were done during the fourth remission period and the third relapse , respectively . - pubmed
these results suggested that autologous BMT with these three antibodies may be an effective mode of therapy for Null - ALL patients . - pubmed
An immunofluorescence study on the humoral immunity to adult human oral mucosa in recurrent aphthous stomatitis . - pubmed
Lipoperoxidation after carbon tetrachloride poisoning in rats previously treated with antioxidants . - pubmed
Aggressive behavior of chimpanzees and baboons in natural habitats . - pubmed
[ Study of the cardiac output in 12 patients with pheochromocytoma ] . - pubmed
The biochemical characteristics of the fracture hematoma in man . - pubmed
Equilibria for inversions induced by x - rays in isogenic strains of Drosophila pseudoobscura . - pubmed
The method consists of applying rhodamine - labeled whole bacteria to frozen sections of tissue in which inflammation had been induced by injection of the same bacterial strain . - pubmed
, the same bacteria used to induce the tissue inflammation ) decreased binding of the labeled bacteria to a significant extent . - pubmed
Primary cell cultures of normal human epidermal keratinocytes and melanocytes and human cell lines established from a primary melanoma ( SK - PM-4 ) and metastatic melanomas ( HO # 1 , SK - MEL21 , and SK - MEL37 ) contain specific and saturable receptors for the tumor promoter phorbol dibutyrate ( PDBu ) . - pubmed
The binding of [ 3H ] PDBu to human keratinocytes was inhibited by the tumor promoters 12 - O - tetradecanoylphorbol 13 - acetate and teleocidin but not by phorbol , which lacks tumor - promoting activity . - pubmed
The sensitivity of an enzyme - linked immunosorbent assay ( ELISA ) to detect pure native Escherichia coli heat - stable toxin ( ST ) and to identify ST - producing strains among clinical isolates was determined . - pubmed
coli strains tested of human origin , which had been shown elsewhere by DNA hybridization probes to have ST - coding genes of either human or porcine origin , and in all of three ST - producing E. - pubmed
coi strains tested of porcine origin . - pubmed
The concomitant use of both ST and LT ELISAs provides a rapid , simple , and sensitive method for identifying among clinical isolates enterotoxigenic strains of E. - pubmed
Enzymatic changes in dystrophic mice and their age dependency . - pubmed
In most cases the activity of these enzymes was significantly elevated in the muscle of the dystrophic mice . - pubmed
The enzymatic changes in the bone of the dystrophic mice were milder but more or less analogous to those in muscle . - pubmed
As compared with cellular immunity tests , serological tests more frequently detect virus - specific immune response in humans immunized with concentrated purified vaccine ( CV ) against tick - borne encephalitis . - pubmed
Serum copper and zinc levels in melanoma patients . - pubmed
However , not all patients who died from tumor metastases displayed persistent elevations of SCL . - pubmed
Computed tomography performed before and during treatment showed the occurrence of tumor shrinkage in 18 patients ( 62 % ) , but in no case was a complete disappearance of the tumor observed . - pubmed
In 5 of these patients , it was even possible to document tumor shrinkage within the first month of treatment with low doses of the dopamine agonists , whereas in other patients , tumors shrank only after prolonged treatment with higher doses . - pubmed
Visual field and acuity improved or normalized in 8 of the 13 patients with visual defects ; in some cases , the improvement was reported as early as 2 days after the treatment was started . - pubmed
In considering the high percentage of patients showing tumor shrinkage under medical treatment , we propose a course with dopamine agonists as the first step in the management of patients with macroprolactinomas regardless of the presence of visual impairments . - pubmed
CONCLUSIONS : Use of antimicrobial agents for treating vaginitis and cervicitis do not cause a decrease in vaginal colonization by Lactobacillus , which is detectable 1 week to 1 month after treatment . - pubmed
The genotoxic effects of low concentrations of Se ( IV ) , Hg2 + , and CH3HgCl added separately or together ( Se ( IV )/ CH3HgCI ) were studied by determining the induction of micronuclei in the binucleated erythrocytes of Prussian carp . - pubmed
In this article thyroid metastasis in a patient who was operated 11 years ago for renal cell carcinoma is reported with the review of the literature . - pubmed
The immunohistochemical analysis using the monoclonal antibodies to the blood group antigens was performed on the tissues of 387 colorectal cancers and 307 normal colonic tissues , and the relation between expression of these antigens and prognosis of the patients with stage 2 was also investigated . - pubmed
This senile angiopathy is often , but inconstantly , associated with Alzheimer ' s disease , and rarely causes intracerebral hemorrhage , which is typically lobar and recurrent , occurring in elderly normotensive patients with ou without dementia . - pubmed
Risk factors for development of rhegmatogenous retinal detachment in patients with cytomegalovirus retinitis . - pubmed
We studied 259 patients to determine the time - dependent risk and risk factors for the development of retinal detachment in patients with cytomegalovirus retinitis . - pubmed
A case of multifocal reflex sympathetic dystrophy ( RSDS ) in a patient with the tarda form of osteogenesis imperfecta is described , followed by a review of the literature . - pubmed
Microfractures of the trabecular bone in these patients are proposed to be the initial stimulus in the pathogenesis of RSDS by a mechanism similar to the one involved in the pathogenesis of RSDS complicating other diseases associated with bone fragility . - pubmed
Between 65 % and 80 % of patients have had significant improvement in terms of generalized seizure control . - pubmed
Although demonstrable in all patients , these rarely have been problematic and in nearly all instances have been outweighed by the benefit in terms of seizure control . - pubmed
EEG with co - registered electrocardiography was recorded during at least two interictal epileptiform EEG discharges in each of 11 patients who later suffered from sudden unexpected death in epilepsy ( SUDEP ) , and from another 11 age and sex matched patients , also with uncontrolled tonic - clonic seizures , drawn from the same centre who were still alive at the time of investigation ( non - SUDEPs ) . - pubmed
These agents have a useful role as selective pharmacologic research probes , and some of them can be used therapeutically as potent and selective anti - nausea and antiemetic drugs , particularly in patients undergoing cancer chemotherapy treatment or general anesthesia procedures . - pubmed
We report herein the case of a 54 - year - old woman with a moderate bleeding tendency , diagnosed as an EDTA - dependent pseudothrombocytopenia associated with a congenital platelet release defect . - pubmed
The recent correct diagnosis of a false thrombocytopenia stimulated further laboratory investigation on the cause of the patient 's bleeding tendency with the consequent identification of a congenital platelet deficiency of the arachidonic acid pathway . - pubmed
This finding is of relevant importance for the management of the patient in case of elective surgery or hemorrhagic emergency . - pubmed
A meta - analysis of 12 selected randomized trials was performed to assess the efficacy of beta - blockers in the prevention of rebleeding and the effect on long - term survival in patients with cirrhosis . - pubmed
Beta - blockers significantly increased the mean percentage of patients free of rebleeding ( 21 % mean improvement rate , CI 95 % : 10%-32 % , P & lt ; .001 , relative risk 1.42 ) , the mean percentage of patients free of variceal rebleeding ( 20 % mean improvement rate , CI 95 % : 11%-28 % , P & lt ; .001 ) , the mean survival rate ( 5.4 % mean improvement rate , CI 95 % : 0%-11 % , P = .05 , relative risk 1.27 ) , the mean percentage of patients free of bleeding death ( 7.4 % , CI 95 % : 2%-13 % , P & lt ; .01 , relative risk 1.50 ) . - pubmed
Five patients would need to be treated with beta - blockers to prevent one rebleeding episode , 14 treated to prevent one death , and 13 treated to prevent one death from bleeding . - pubmed
In patients with esophageal varices , beta - blockers significantly increase the mean percentage of patients free of rebleeding and the mean survival rate at 2 years . - pubmed
Patients with uncomplicated deep vein thrombosis and healthy controls were investigated as comparison groups . - pubmed
Nitric oxide gas is a potent inhibitor of platelet aggregation , with an IC50 of 3.6 microM for rabbit platelets . - pubmed
Mycoplasma penetrans was shown to be associated with HIV infection and recent data have indicated the capacity of this mycoplasma to activate different functions of the immune system . - pubmed
Normal tissue derived from human brain and tumor - cell lines derived from colon , ovary , and breast were not reactive . - pubmed
Arterial vasodilation and vascular connective tissue changes in spontaneously hypertensive rats . - pubmed
We evaluated the arterial connective tissue response of 16 - week - old spontaneously hypertensive rats ( SHRs ) to treatment with minoxidil , 120 mg / L , drinking water for 10 weeks . - pubmed
However , in addition to working as a cardioprotective agent , DEX has other potential applications that are outlined below and include ( 1 ) treatment of patients with acquired immunodeficiency syndrome - related Kaposi ' s sarcoma , based on its activity as an angiogenesis inhibitor ; ( 2 ) enhancement of the effects of cisplatin , based on its ability to increase the antiproliferative effects of cisplatin on human ovarian cancer cells ; ( 3 ) use for treatment of iron overload states in patients who are allergic to deferoxamine ; ( 4 ) treatment of patients with psoriasis ; ( 5 ) protection from hyperoxic effects on the lungs ; ( 6 ) protection from bleomycin - induced pulmonary fibrosis ; ( 7 ) attenuation of acetaminophen - induced hepatotoxicity ; ( 8) prevention of mucositis ; and ( 9 ) other applications . - pubmed
Adrenal - cortex autoantibodies and steroid - producing cells autoantibodies in patients with Addison ' s disease : comparison of immunofluorescence and immunoprecipitation assays . - pubmed
We studied 165 patients with Addison ' s disease : 143 patients had different forms of autoimmune Addison ' s disease ( 13 with idiopathic premature ovarian failure ) and 22 had nonautoimmune Addison ' s disease . - pubmed
A high association between these two markers in patients with different forms of autoimmune Addison ' s disease and in those with short- or long - standing disease was found . - pubmed
Determinants and predictors of the maximum walking speed during computer - assisted gait training in hemiparetic stroke patients . - pubmed
PARTICIPANTS : Thirty - four male hemiparetic stroke patients received 8 weeks of computer - assisted gait training ( CAGT ) , which was initiated within approximately 3 months after stroke onset . - pubmed
Presarcomatous lesions of experimentally induced sarcomas in rats : morphologic , histochemical , and immunohistochemical features . - pubmed
The present study , therefore , investigated the early phases of experimentally induced rat sarcoma , which closely resembles human malignant fibrous histiocytoma ( MFH ) . - pubmed
Control animals injected with olive oil revealed acute inflammatory reactions after 30 days and no signs of chronic inflammation or malignancy after 60 and 120 days . - pubmed
We concluded that these experimentally - induced rat sarcomas develop in a triphasic pattern that resembles non - healing granulation tissue , with neovascularization preceding the occurrence of overt MFH . - pubmed
PATIENTS AND METHODS : Cytological samples were obtained by brushing biliary strictures via a guide wire in 86 patients with strictures of unknown status . - pubmed
The overall specificity of less than 100 % resulted from dysplasia in two patients with chronic pancreatitis and inflammatory mass . - pubmed
Selecting antihypertensive therapy in the pregnant woman with diabetes mellitus . - pubmed
The choice of an antihypertensive agent for the pregnant woman with diabetes involves many factors . - pubmed
In addition to playing key roles in the morphogenesis and sculpting of the organs to give rise to highly specialized forms and shapes , cell death also participates in the programmed creation of specialized cell types for essential functions such as the selection of B cells in the immune system of mammals and the formation of tracheids in the xylem of vascular plants . - pubmed
Tobacco use prevalence and definitions and diagnoses of nicotine addiction and dependence are described . - pubmed
Effect of ethanol on polyunsaturated fatty acid biosynthesis in hepatocytes from spontaneously hypertensive rats . - pubmed
We investigated the effects of ethanol on PUFA biogenesis in hepatocytes of Wistar Kyoto ( WKY ) rats and Spontaneously Hypertensive Rats ( SHR ) . - pubmed
Free amino acid concentration in hydatid cyst fluids from fertile and infertile human and animal Echinococcus granulosus . - pubmed
11 free amino acids from fertile ( sheep origin ) , nine from infertile ( cattle origin ) , 13 from infertile ( human origin ) hydatid cyst fluids and 19 amino acids from sera of patients with hydatid infection were detected . - pubmed
Glycine level in the fertile hydatid cyst fluids ( sheep origin ) was significantly higher than those of infertile cysts fluids ( cattle and human origin ) and sera with hydatid patients . - pubmed
Glycine level in fertile hydatid cyst fluids was about two times more concentrated in infertile cattle cyst fluids , 10 times more concentrated in infertile human hydatid cyst fluids and 13 times more concentrated in sera with hydatid patients . - pubmed
On the other hand , alanine and valine concentration in the fertile and infertile cyst fluids were at similar level with the exception that valine level in fertile cyst fluids was 12 times more concentrated in infertile human cyst fluids . - pubmed
Our findings with respect to fertile and infertile cysts fluids showed that free amino acids concentrations in cyst fluids were significantly , higher in sera from patients with hydatid cyst . - pubmed
Total amount of free amino acids content in fertile and infertile cyst fluids was three to eight times higher from that of human sera with hydatid patients . - pubmed
[ Morphological picture of alimentary tract in the process of food allergy in children ] . - pubmed
Morphological and histopathological changes in the mucosa of the stomach , duodenum and small and large intestine have been evaluated in 83 children aged between 12 months and 15 years with diagnosed food allergy . - pubmed
Among 23 children aged 7 - 15 years , in whose clinical picture abdomen pains dominated , endoscopic examination of upper part of alimentary tract was performed . - pubmed
In 43 children aged 12 months--8 years with dominating symptoms of protracted diarrhoea and/or body mass deficiency , biopsy of small intestine mucosa was examined . - pubmed
In 13 children ( 30.2 % ) subtotal villus atrophy was observed , in 14 children ( 32.5%)--partial and in 16 children ( 37.3 % ) no small intestine mucosa atrophy was noticed . - pubmed
Large intestine inflammation was observed in food allergy process in 7 children . - pubmed
Over 2/3 of examined children with food allergy showed inflammation and inflammation - atrophical changes in alimentary tract mucosa . - pubmed
Arcanobacterium pyogenes , a common inhabitant of the mucosal surfaces of cattle and swine , is also a pathogen associated with a variety of infections in these animals . - pubmed
Ventricular coupling of electrical and mechanical dyssynchronization in heart failure patients . - pubmed
We studied the relationships of electrical and mechanical synchronization in patients with heart failure ( CHF ) and various degree of ventricular conduction delays . - pubmed
In CHF patients , electromechanical and contractile alterations are coupled ; regional activation may be an early parameter allowing the detection of ventricular dyssynchronization . - pubmed
For the in vivo studies , male Sprague - Dawley rats underwent laparotomy , and small intestinal ischemia was induced by clamping the superior mesenteric artery for 30 or 60 minutes , after which reperfusion was allowed for various time points up to 4 days . - pubmed
METHODOLOGY : We studied 117 subjects with chronic hepatitis C who failed treatment with interferon - alpha , 87 of whom were " non - responders " and 30 " relapsers . " - pubmed
METHOD : We performed a search of the published literature to identify all eligible articles pertaining to the surgical management of coexisting cataract and glaucoma in adults . - pubmed
The evidence was weak that extracapsular cataract extraction ( ECCE ) alone results in short - term increase in IOP and was insufficient to determine the short - term impact of phacoemulsification cataract extraction ( PECE ) on IOP in glaucoma patients . - pubmed
Long - term survival of patients given hormonal therapy for metastatic endometrial stromal sarcoma . - pubmed
Endometrial stromal sarcoma ( ESS ) is a rare neoplasm , mainly observed in premenopausal women . - pubmed
We describe two women 44 and 34 years old at the time ESS diagnosis , who developed lung metastases 3 and 6 years , respectively , after initial treatment : hysterectomy without ( case 1 ) or with oophorectomy ( case 2 ) , followed by hormone replacement therapy ( HRT ) for the latter . - pubmed
The aminotetraline derivative ( + /-)-( R , S )- 5,6 - dihydroxy-2 - methylamino-1,2,3,4 - tetrahydro - naphthalene hydrochloride ( CHF-1024 ) displays cardioprotection in postischemic ventricular dysfunction of the rat heart . - pubmed
A model of isolated and perfused ( 15 ml / min ) electrically driven ( 300 beats / min ) rat heart subjected to global ischemia ( 1 ml / min for 20 min ) and reperfusion ( 15 ml / min for 30 min ) was followed . - pubmed
Stomatitis of cattle and horses due to yellow bristle grass ( Setaria lutescens ) . - pubmed
Ringworm epizootics in laboratory mice and rats : experimental and accidental transmission of infection . - pubmed
Treatment of experimental tuberculosis of the guinea pig with dihydrostreptomicine and simultaneously with substances acting on the host . - pubmed
Articular layer geometry , previously acquired from human cadaver joints , was used in conjunction with computer - aided design and manufacturing technology to create these anatomically accurate molds . - pubmed
Bladder augmentation ( 15 ) , bladder neck reconstruction ( 7 ) , fascial sling ( 3 ) , ureteral reimplants ( 1 ) , revision of epispadias ( 2 ) and/or redo orchiopexy ( 1 ) were concurrently performed in 19 patients . - pubmed
Subjects with a clinical history of seasonal allergic conjunctivitis ( but no current symptoms or treatment at baseline ) were studied . - pubmed
At visit 2 ( 2 weeks later ) , subjects were rechallenged to confirm the allergic response . - pubmed
The study comprised 48 patients ( 38 women and 10 men ) aged from 18 to 87 years , in whom thin needle aspiration biopsy revealed cancer of the thyroid . - pubmed
Postoperative histopathological examination showed papillary cancer in 35 patients , oxyphilic cancer in 5 patients , anaplastic cancer in 4 and medullary cancer in 4 patients . - pubmed
A multicenter , placebo - controlled , double - blind study of efficacy of a new form of carbamazepine ( Carbatrol ) in refractory epileptic patients . - pubmed
CBR was evaluated in 47 patients with uncontrolled partial onset seizures . - pubmed
During the 28 - day baseline period , patients were required to have at least two seizures and to take CBZ at a therapeutic level , a second antiepileptic drug was allowed but not valproic acid ( VPA ) . - pubmed
CASE REPORT : The patient was a 10 year old male with an acquired esotropia of 20 PD at distance . - pubmed
CONCLUSION : The slipped muscle may have been caused by insufficient suture and/or excessive rubbing of the eye by the patient . - pubmed
Beneficial effects of fluvastatin following percutaneous coronary intervention in patients with unstable and stable angina : results from the Lescol intervention prevention study ( LIPS ) . - pubmed
AIMS : To investigate the effect on risk of major adverse cardiac events ( MACE ) of lipid lowering treatment with fluvastatin 80 mg / day after a first percutaneous coronary intervention in patients with stable and unstable angina . - pubmed
METHOD AND RESULTS : This prespecified subgroup analysis of the LIPS ( Lescol intervention prevention study ) analysed 1658 patients with documented diagnosis ; 824 had unstable angina ( 417 randomly assigned to fluvastatin , 407 to placebo ) and 834 had stable angina ( including silent ischaemia ; fluvastatin , 418 ; placebo , 416 ) . - pubmed
Fluvastatin treatment reduced the risk of MACE by 28 % compared with placebo ( p = 0.03 ) among patients with unstable angina , with no difference between patients with stable and patients with unstable angina ( relative risk 1.07 , 95 % confidence interval 0.87 to 1.30 , p = 0.53 ) . - pubmed
Fluvastatin reduced coronary atherosclerotic events ( MACE excluding restenosis ) by 36 % ( p = 0.006 ) among patients with unstable angina and 31 % ( p = 0.02 ) among patients with stable angina . - pubmed
CONCLUSION : Treatment with fluvastatin 80 mg / day produced significant reductions in MACE and coronary atherosclerotic events after percutaneous coronary intervention in patients with average cholesterol concentrations . - pubmed
The beneficial effects of fluvastatin are observed in patients with unstable or stable angina alike . - pubmed
Simvastatin has the best evidence for its effectiveness in patients without CHD ; in contrast , atorvastatin has possibly more benefits for patients with clinically evident CHD . - pubmed
The virulent , uncloned challenge stock , SIVsmE660 , represented a type of heterologous challenge and the intrarectal challenge modeled infection across a mucosal surface . - pubmed
Clostridium cadaveris bacteraemia : two cases and review . - pubmed
We present 2 rare cases of bacteraemia with C. - pubmed
[ The influence of hyperthyroidism and glucocorticosteroid treatment on bone metabolism in patients with Graves ' disease and ophthalmopathy ] . - pubmed
UNLABELLED : The aim of the study was to assess influence of hyperthyroidism and glucocorticosteroid treatment on changes of bone turnover markers in patients with Graves ' disease and thyroid ophthalmopathy ( TO ) . - pubmed
Group I was composed of 26 euthyroid Graves ' disease patients with TO suitable for steroid treatment . - pubmed
Early identification and treatment of such individuals is essential to reduce transmission ; however , genetic and immunological correlates of disease progression have not been well established in man . - pubmed
The murine model has been a central tool for the elucidation of protective immune mechanisms that are essential for controlling M. - pubmed
Additionally , the study of inbred mice has revealed significant divergence in the susceptibility and disease progression of individual mouse strains to an infection with M.tuberculosis . - pubmed
The continued study of genetically disparate mouse strains has the potential to identify immune mechanisms that correlate with increasing susceptibility to tuberculosis . - pubmed
These mechanisms will be highly applicable to studies in man and assist in the early detection of individuals that are more vulnerable to the development of reactivation tuberculosis . - pubmed
In a double - blind comparison of the therapeutic effect of amantadine in a natural outbreak of Hong Kong influenza in January 1969 near Houston , Texas , the decrease in titers of virus in throat swabs from 12 treated patients during the first 10 hr of treatment was appreciably greater than similar titers of virus from 16 untreated patients ( P = 0.06 ) . - pubmed
Cough , sore throat , and nasal obstruction cleared more rapidly in treated patients ( P & lt ; 0.05 ) , and decline of fever in 6 treated patients sick for less than 48 hr before treatment was more rapid than among 13 untreated patients who had been ill for less than 48 hr . - pubmed
To test this hypothesis , we assessed brain acetate metabolism in five well - controlled type 1 diabetic subjects and six nondiabetic control subjects using 13C magnetic resonance spectroscopy during infusions of [ 2 -( 13 ) C ] acetate during hypoglycemia ( approximately 55 mg / dl ) . - pubmed
Brain acetate concentrations were over twofold higher in the subjects with diabetes than the control subjects ( P = 0.01 ) . - pubmed
The fraction of oxidative metabolism from acetate ( P = 0.015 ) and the rate of MCA transport ( P = 0.01 ) were also approximately twofold higher in the diabetic subjects . - pubmed
We conclude that during hypoglycemia MCA transport in the brain was increased by approximately twofold in patients with well - controlled type 1 diabetes , as reflected by higher brain acetate concentrations and rates of acetate oxidation . - pubmed
These data are consistent with the hypothesis that upregulation of MCA transport may contribute to the maintenance of brain energetics during hypoglycemia in patients with type 1 diabetes . - pubmed
[ Study on pathogenic bacteria in lung infection during mechanical ventilation for patients with acute organophosphorus pesticide poisoning ] . - pubmed
METHOD : In this article , we report some of the results from a study including 41 women , aged 37 - 69 years old , with nonmetastatic primary breast cancer , referred to the Department of Oncology at Umea University Hospital in Sweden for postoperative radiotherapy . - pubmed
RESULTS : No anastomotic leaks or systemic complications were observed in the ECM - treated animals . - pubmed
METHODS : The records of 18 patients with proven histological diagnosis of hepatobiliary and pancreatic tuberculosis were reviewed retrospectively . - pubmed
RESULTS : Of 18 patients ( 11 men ) , 11 had hepatobiliary TB while 7 had pancreatic TB . - pubmed
Five patients ( 28 % ) had associated extra - abdominal TB which helped in preoperative diagnosis in 3 patients . - pubmed
Imaging demonstrated extrahepatic bile duct obstruction in the patients with jaundice and in addition picked up liver , gallbladder and pancreatic masses with or without lymphadenopathy ( peripancreatic / periportal ) . - pubmed
Two patients developed significant postoperative complications ( pancreaticojejunostomy leak 1 intraabdominal abscess 1 ) and 3 developed ATT induced hepatotoxicity . - pubmed
CONCLUSION : Tuberculosis should be considered as a differential diagnosis , particularly in young patients , with atypical signs and symptoms coming from areas where tuberculosis is endemic and preoperative tissue and/or cytological diagnosis should be attempted before labeling them as hepatobiliary and pancreatic malignancy . - pubmed
Here , we demonstrate for the first time the antitumor effects of FK in murine hepatocellular carcinoma ( HCC ) by constructing a FK eukaryotic expression vector ( pIRES - FK ) and transferring it into such tumor cells . - pubmed
Tumor rejection experiments were performed by injecting FK gene - modified murine HCC cell line ( MM45T.Li ) into immunocompetent mice , which significantly inhibited tumorigenicity or growth of MM45T.Li - FK cells . - pubmed
Splenic lymphocyte from mice treated with MM45T.Li - FK were effective in the induction of tumor - specific cytotoxic T cells . - pubmed
Fischer-344 ( F344 ) rats exhibit proteinuria and insulin resistance in the absence of hypertension as they age . - pubmed
A recent case of basilar artery occlusion ( BAO ) in a 62 - year - old woman is presented , along with a review of the literature on the clinical aspects of the disorder and treatment options . - pubmed
Ten patients with head and neck squamous cell cancer underwent resection of the tumour followed by microvascular reconstruction with a free flap . - pubmed
Segmental urethral dosimetry and urinary toxicity in patients with no urinary symptoms before permanent prostate brachytherapy . - pubmed
Acinetobacter baumannii infections in a surgical intensive care unit : predictors of multi - drug resistance . - pubmed
Patients with multi - resistant infection , susceptible exclusively to colistin , were compared with those sustaining non - multi - drug resistant infection . - pubmed
RESULTS : Among 411 patients , 52 ( 12.6 % ) developed Acinetobacter infection . - pubmed
CONCLUSION : Acinetobacter baumannii infections are frequent and associated with high morbidity , mortality , and multi - resistance . - pubmed
METHODS : 114 atherosclerotic patients ( 100 males , 61.7+/-6.7 years ) were included undergoing elective coronary revascularisation using the radial artery of the non - dominant forearm with non - pathological Allen 's Test . - pubmed
Biomarkers of inflammation in patients with unclassified polyarthritis and early rheumatoid arthritis . - pubmed
Irish wolfhounds ( IW ) and other large breed dogs are most commonly disposed to DCM . - pubmed
In order to rule out a breed - specific haplotype that predisposes to DCM , the polymorphisms were genotyped in 24 Elo dogs , a breed mix established from nine different breeds . - pubmed
Sixteen percent of all head and neck cancer patients experienced a distant metastasis of their primary tumour . - pubmed
Although short - term survival is high , nearly half of all patients will develop metastasis or die of complications of local recurrences . - pubmed
DESIGN : Two hundred fifty - five clinically stable schizophrenia outpatients were randomly selected in Hong Kong and their counterparts matched according to sex , age , age at onset , and length of illness were recruited in Beijing , China . - pubmed
PATIENTS OR PARTICIPANTS : Clinically stable schizophrenia outpatients . - pubmed
METHODS : We performed a case - control association study including 118 Hungarian patients with JIA and 118 sex - matched healthy controls . - pubmed
Also revealed was the influence of viral replication of hepatitis B virus in the development of complications , including hepatocarcinoma . - pubmed
The importance of fatty acid liver disease was clearly shown in several studies confirming the influence of diabetes in the presence of inflammation and fibrosis and the increase in the indication of liver transplantation for this disease , which may recur in the graft , especially in patients with a high body mass index . - pubmed
METHODS : Dysraphism was surgically created in 2 groups of 48 rat fetuses ; group 1 : control , and group 2 : treated with corticosteroid . - pubmed
Thirty - four formalin - fixed and 19 fresh frozen hepatitis B virus ( HBV)-related cirrhosis samples were examined for the presence of LLCC , small liver cell change ( SLCC ) , and hepatocellular carcinoma ( HCC ) . - pubmed
The characteristics of HBV - related LLCC are more consistent with dysplastic rather than merely reactive hepatocytes , whereas cholestatic LLCC more likely represents reactive change with more stringent cell cycle checkpoint control . - pubmed
Although product safety regarding HIV , hepatitis , and other blood - borne infections is currently excellent , potential new infectious agents require continued vigilant monitoring . - pubmed
An examination of chimpanzee use in human cancer research . - pubmed
Given that cancer is a leading cause of human death worldwide , one might expect that if chimpanzees were needed for , or were productive in , cancer research , then they would have been widely used . - pubmed
This comprehensive literature analysis reveals that chimpanzees have scarcely been used in any form of cancer research , and that chimpanzee tumours are extremely rare and biologically different from human cancers . - pubmed
Papers describing potential new cancer therapies noted significant concerns regarding the chimpanzee model . - pubmed
It would therefore be unscientific to claim that chimpanzees are vital to cancer research . - pubmed
On the contrary , it is reasonable to conclude that cancer research would not suffer , if the use of chimpanzees for this purpose were prohibited in the US . - pubmed
Genetic differences between humans and chimpanzees , make them an unsuitable model for cancer , as well as other human diseases . - pubmed
Verminous pneumonia in dogs and cats . - pubmed
METHODS : 108 subjects presenting a first DSM - III - R manic episode with psychotic features were assessed at baseline and 12 months after stabilisation on symptoms and functional characteristics , and patients with BD ( n=87 ) were compared with those with SA bipolar subtype ( SAB ) ( n=21 ) . - pubmed
RESULTS : SAB patients had a higher prevalence of first degree relatives with schizophrenia and a lower premorbid functional level . - pubmed
At stabilisation and 12 months after stabilisation , SA patients had higher levels of negative symptoms , with poorer functional level at 12 months . - pubmed
CONCLUSIONS : These data suggest SA is a valid diagnosis in the early phase of psychotic disorders considering it defines a subgroup of first episode psychotic mania patients with distinct characteristics compared to BD . - pubmed
The cardiological evaluation of patients with cerebral ischaemia is of great clinical importance because diseases of the heart and aorta represent important sources of embolism , because ischaemic stroke is an index event that can lead to the diagnosis of cardiovascular diseases and because the mortality and morbidity of stroke patients are determined by concomitant cardiac diseases . - pubmed
Brachial - ankle pulse wave velocity as a risk stratification index for the short - term prognosis of type 2 diabetic patients with coronary artery disease . - pubmed
The incidence of diabetes is increasing , and the disease has become an important predictor of prognosis in patients with coronary artery disease ( CAD ) , although adverse events often occur without warning . - pubmed
This study tests the hypothesis that brachial - ankle pulse wave velocity ( baPWV ) , a marker for arterial stiffness obtained by simple and noninvasive automated devices , can be a risk stratification index to predict prognosis in diabetic patients with CAD . - pubmed
Data were available on 564 CAD patients , with a median follow - up of 25.4 months . - pubmed
The higher baPWV among diabetic patients was defined as a median baPWV of 1730 cm s(-1 ) or more . - pubmed
The 3 - year Kaplan - Meier estimates of event - free survival were 72.8 % in diabetic patients with lower baPWV and 51.3 % in those with higher baPWV , respectively ( P=0.031 ) . - pubmed
Recent studies have shown that whole - body vibration improves posture and gait control in stroke patients . - pubmed
Patients with degenerative cerebellar disease suffer from ataxic gait also which is characterised by the variation of gait pattern . - pubmed
In this retrospective data analysis , we report on the use of adrenaline in 20 neonates with birth asphyxia and shock that was refractory to dopamine and dobutamine . - pubmed
Selective serotonin ( 5 - HT ) re - uptake inhibitors ( SSRIs ) are commonly used in the treatment of generalized anxiety disorder in Humans . - pubmed
However , because only few animal models display overt anxious - like behavior , detailed preclinical studies of the anxiolytic properties of antidepressants are still lacking . - pubmed
Deletion of both receptors resulted in ( i ) higher emotionality of animals , as observed in three unconditioned paradigms of anxiety ( open field , elevated plus maze and novelty suppressed feeding tests ) ; ( ii ) a 200 % increase in the mean spontaneous firing rate of 5 - HT neurons in the dorsal raphe nucleus ( DRN ) compared to 5 - HT(1A/1B)+/+ mice ; ( iii ) elevated basal dialysate levels of 5 - HT in the DRN and frontal cortex ; ( iv ) an exaggerated response to acute paroxetine administration in microdialysis experiments , and ( v ) increased basal core body temperature . - pubmed
METHODS : Twenty - four patients with coronary disease and left ventricular systolic dysfunction ( ejection fraction & lt;45 % ) underwent RTMCE before and 3 months after CABG . - pubmed
In order to study the effect of aging on T - H - induced mitochondrial dysfunction , we recently developed a rodent mitochondrial genechip with probesets representing mitochondrial and nuclear genes contributing to mitochondrial structure and function . - pubmed
CONTEXT : This article reviews diverse aspects of the prevention of urinary tract infections , including confirmation of the diagnosis , application of hygiene and dietary measures , antibacterial prophylaxis ( preferably consisting of a single nocturnal oral dose per day of an antibiotic or drug with high urinary excretion and good tolerance ) , and administration of vaccines made with Escherichia coli and other Gram - negative bacilli , consisting of immunostimulating fractions of E. - pubmed
coli strains or E. - pubmed
Propagation of herpes simplex virus via pontine fiber in a case of brainstem encephalitis . - pubmed
OBJECTIVE : To explore the mechanism of protective effect of Sphingosine-1 - phosphate(S1P ) in cultured neonatal rat cardiomyocytes dining simulated hypoxia / reoxygenation . - pubmed
CONCLUSION : SiP can obviously restrain apoptosis in curtured rat neonatal cardiomyocytes during simulated hypoxia / reoxygenation . - pubmed
PARTICIPANTS : 10 840 patients newly prescribed tiotropium ( n=4767 ) or LABA ( n=6073 ) , at least 40 years old , and not having asthma as their only respiratory illness . - pubmed
Adding HPV testing to cytology screening reduced & gt;= grade 3 cervical intraepithelial neoplasia at 5 years . - pubmed
Intravenous drug use ( adjusted odds ratio [ ( adj ) OR ] , 30.5 ; 95 % confidence interval [ CI ] , 18.9 - 49.1 ) , cohabitation or sexual partnership with an hepatitis C virus ( HCV ) carrier ( ( adj ) OR , 11.2 ; 95 % CI , 6.6 - 19.2 ) , nosocomial exposure ( ( adj ) OR , 6.6 ; 95 % CI , 4.6 - 9.4 ) ; unsafe sexual practices ( ( adj ) OR , 3.1 ; 95 % CI , 1.9 - 5.2 ) , and cosmetic treatments with percutaneous exposure ( ( adj ) OR , 1.7 ; 95 % CI , 1.2 - 2.4 ) were independently associated with acute hepatitis C. - pubmed
LCH most commonly occurs as a localised solitary bone lesion and appears predominantly in paediatric patients . - pubmed
The presenting features of the patient included fever , bleeding gums and seborrheic dermatitis - like rash . - pubmed
The patient had poor LV function along with moderate pulmonary hypertension . - pubmed
Extending helminth control beyond STH and schistosomiasis : the case of human hymenolepiasis . - pubmed
The mean age of the patients at the time of trauma was 9.83 + - 2.8 years . - pubmed
Safety and immunogenicity of booster immunization with 7 - valent pneumococcal conjugate vaccine in children with idiopathic nephrotic syndrome . - pubmed
Safety and immunogenicity of a booster dose of 7 - valent pneumococcal conjugate vaccine ( PCV7 ) were evaluated in 29 patients with idiopathic nephrotic syndrome ( INS ) , who had been primed 12 months earlier with one dose of PCV7 . - pubmed
PCV7 was not associated with increased risk of INS relapse ( RR=0.77 , p=0.8 ) and serotype - specific antibodies increased in all subjects at 1 month ( p<0.01 ) . - pubmed
Additional PCV7 doses could be safely given in children with INS to increase circulating antibodies above the protective threshold . - pubmed
However , its expression pattern and biological roles in human ovarian cancers are not clear . - pubmed
Together , these findings implicate GEMMs as powerful preclinical tools with the capacity to recapitulate relevant human disease biology , and support the use of genetic signatures generated in these models to facilitate future drug discovery and validation efforts . - pubmed
We studied the longitudinal growth of the short bones in the hand of a 15 - yr - old girl with PHP type Ia who had been followed for congenital hypothyroidism . - pubmed
Plasmodium vivax , the pathogen causing endemic malaria in humans worldwide , is responsible for extensive disease morbidity . - pubmed
These drugs with novel scaffolds may act as potent drugs for treating malaria caused by P. - pubmed
Reversion by vitamin E treatment of the oxidative damage but not of the advancement in reproductive senescence produced by neonatal hypoxia or hypoxia - ischemia in female rats . - pubmed
Previously we described advanced reproductive senescence ( premature loss of regular cyclicity ) in female rats subjected to perinatal H or H plus unilateral ischemia ( HI ) associated with changes in the hypothalamic expression of estrogen and opioid receptors . - pubmed
Effect of the aqueous extract of Foeniculum vulgare ( fennel ) on the kidney in experimental PCOS female rats . - pubmed
In this research , renoprotective effect of the aqueous extract of Foeniculum vulgare ( AEF ) in experimental PCOS female rats is studied . - pubmed
Animals in the second group were non poly cystic ovary syndrome ( PCOS ) rats which were treated with intragastric administration of aqueous extract of F. - pubmed
RESULTS : The mean values of blood urea nitrogen in PCOS rats treated with low dose of AEF and EV and non - treated , was significantly ( p<0.05 ) increased compared with non - PCOS and PCOS rats treated with high dose of AEF . - pubmed
Moreover , histopathological changes of kidney samples were comparable in PCOS rats with respect to treated groups with AEF . - pubmed
on renal function in PCOS rats . - pubmed
[ Essential thrombocythemia : baseline characteristics and risk factors for survival and thrombosis in a series of 214 patients ] . - pubmed
Benzbromarone consistently attenuates BK- , formalin- , or monosodium urate - induced inflammatory pain in rat and mouse models . - pubmed
This study looked at antibiotic dosing and treatment failure in the obese population from the primary care perspective and accounts for BMI range , weight , comorbid diabetes , and tobacco use . - pubmed
METHODS : This study was a retrospective chart review of 637 adult primary care patients designed to evaluate rates of treatment failure of outpatient cellulitis among patients of varying BMI . - pubmed
While controlling for age , gender , race , diagnosis of diabetes mellitus , and tobacco use , a BMI of & gt;=50 kg / m(2 ) and a weight & gt;=120 kg was associated with adverse outcomes with an odds ratio of 2.440 ( 95 % CI , 1.260 - 4.724 ; P = .008 ) and 2.246 ( 95 % CI , 1.154 - 4.369 ; P = .017 ) , respectively . - pubmed
CONCLUSIONS : Patients with cellulitis weighing & gt;120 kg or with a BMI & gt;=50 kg / m(2 ) were at greatest risk for treatment failure in the outpatient setting , even when controlling for comorbid diabetes and tobacco use . - pubmed
METHODS : Ninety women between 22 and 36 weeks ' gestation were included and divided into two groups : group A comprised 41 women at 22 to 36 weeks ' gestation who were suffering from threatened premature labor ; and group B comprised 49 women at 22 to 36 weeks ' gestation with preterm premature rupture of the membranes . - pubmed
Gluteal fasciocutaneous ( FC ) rotation flaps can still be used to close sacral pressure ulcers but tend to develop a large dog - ear on the buttock . - pubmed
OBJECTIVE : Epilepsy is a serious , potentially life - shortening brain disorder that occurs in patients of all ages and races . - pubmed
A total of 2 - 4 % of people have experienced seizures at least once in their lifetime . - pubmed
In this manner , we compare the recurrence rates of epilepsy in first seizure patients treated with sodium valproic acid as an antiepileptic drug versus a placebo . - pubmed
MATERIAL & amp ; METHODS : In a randomized clinical trial study , 101 first seizure patients were randomly divided into two groups : one group was treated with antiepileptic drugs ( sodium valproate 200 mg , three times a day ) and the other group was given a placebo . - pubmed
All recurrence cases came from the placebo group , with four patients suffering an additional seizure after four months and between 4 - 6 month follow up . - pubmed
Our results suggest that drug therapy for people after their first seizure attack might reduce the probability of seizure recurrence . - pubmed
BACKGROUND AND OBJECTIVES : Reliability is an essential condition for using quantitative sensory tests ( QSTs ) in research and clinical practice , but information on reliability in patients with chronic pain is sparse . - pubmed
The aim of this study was to evaluate the reliability of different QST in patients with chronic low back pain . - pubmed
METHODS : Eighty - nine patients with chronic low back pain participated in 2 identical experimental sessions , separated by at least 7 days . - pubmed
CONCLUSIONS : Most QST measurements have acceptable reliability in patients with chronic low back pain . - pubmed
Multisite Study of an Implanted Continuous Glucose Sensor Over 90 Days in Patients With Diabetes Mellitus . - pubmed
BACKGROUND : Continuous glucose monitoring ( CGM ) , which enables real - time glucose display and trend information as well as real - time alarms , can improve glycemic control and quality of life in patients with diabetes mellitus . - pubmed
The procedure could be completed in all of the patients but was interrupted in 6 patients in group PF because of desaturation ( 5 ) or sudden patient movement ( 1 ) . - pubmed
This study was aimed at comparing the prevalence and severity of chronic periodontitis of HIV - seropositive patients with that of HIV - seronegative persons using the community periodontal index ( CPI ) . - pubmed
CONCLUSION : HIV - seropositive patients had more severe chronic periodontitis than the HIV - seronegative controls , which was independent of lower education . - pubmed
Grapefruit Derived Flavonoid Naringin Improves Ketoacidosis and Lipid Peroxidation in Type 1 Diabetes Rat Model . - pubmed
BACKGROUND : Hypoglycemic effects of grapefruit juice are well known but the effects of naringin , its main flavonoid on glucose intolerance and metabolic complications in type 1 diabetes are not known . - pubmed
OBJECTIVES : To investigate the effects of naringin on glucose intolerance , oxidative stress and ketonemia in type 1 diabetic rats . - pubmed
METHODS : Sprague - Dawley rats divided into 5 groups ( n = 7 ) were orally treated daily with 3.0 ml / kg body weight ( BW)/day of distilled water ( group 1 ) or 50 mg / kg BW of naringin ( groups 2 and 4 , respectively ) . - pubmed
Letter by Madias Regarding Article , " Three Recurrent Episodes of Apical - Ballooning Takotsubo Cardiomyopathy in a Man " . - pubmed
After uterine and muscle closure but before skin closure , Group A was administered local subcutaneous wound infiltration of Injection ( Inj ) ropivacaine 0.75 % 150 milligram ( mg ) or 20 millilitres(ml ) whereas , group B patients were given a local subcutaneous wound infiltration of Inj magnesium sulphate 750 mg ( 1.5 ml of Inj 50 % Magnesium sulphate ) added to Inj ropivacaine 0.75 % ( 18.5 ml ) making a total volume of 20 ml . - pubmed
RESULTS : Of 510 specimens cultured , the total culture positivity obtained was 11.8 % ( 60 ) encompassing 54 ( 10.6 % ) Mycobacterium tuberculosis and 6 ( 1.2 % ) non - tubercular mycobacteria ( NTM ) . - pubmed
In summary , we found that inter - individual variability in non - coding regions affect the response to hypoxia and could potentially impact on the progression of pulmonary diseases . - pubmed
Antimicrobial properties on tester strains ( Bacillus cereus , Escherichia coli , Staphylococcus aureus and Pseudomonas aeruginosa ) and in vitro anti - proliferative activity were evaluated . - pubmed
The cabbage extracts exhibited antimicrobial activity mainly on the ninth day after the expiry date and retained significant inhibitory effects against colon carcinoma ( CaCo-2 ) cells . - pubmed
Results confirmed that JsAE delayed the onset of seizures and reduced frequency of tonic convulsion and mortality in mice . - pubmed
Fifteen patients , 10 males and 5 females , between 10 - 27 years age with different benign vascular skin lesions i.e.haemangioma ( 3 ) and lymphangioma circumscriptum ( 2 ) were taken up for this study . - pubmed
The patients with granuloma pyogenicum showed excellent response with complete disappearance of the lesions while the patients with haemangiomas , lymphangio - haemangiomas and lymphangioma circumscriptum improved by 70 - 90 % . - pubmed
Transient hypopigmentation and mild scarring were seen in all the patients except in patienls with granuloma pyogenieum . - pubmed
A total of 126 CM patients and 126 healthy individuals were recruited for the study . - pubmed
The CM patients were treated with amphotericin B ( AmB ) . - pubmed
OBJECTIVE : The goal of this study was to investigate the utility of the INECO Frontal Screening ( IFS ) for differentiating bv - FTD patients from patients with Major Depression . - pubmed
RESULTS : Patient groups differed significantly on the motor inhibitory control ( U=437.0 , p<0.01 ) , verbal working memory ( U=298.0 , p<0.001 ) , spatial working memory ( U=300.5 , p<0.001 ) , proverbs ( U=341.5 , p<0.001 ) and verbal inhibitory control ( U=316.0 , p<0.001 ) subtests , with bv - FTD patients scoring significantly lower than patients with depression . - pubmed
CONCLUSION : Our results suggest the IFS can be considered a useful tool for detecting executive dysfunction in both depression and bv - FTD patients and , perhaps more importantly , that it has the potential to help differentiate these two conditions . - pubmed
Children with Wiskott - Aldrich syndrome are often initially diagnosed with immune thrombocytopenic purpura , which can lead to inappropriate treatment and delays to life - saving definitive therapy . - pubmed
We unravel several taxonomic confusions and uncertainties in the earlier literature that had their origins in the classification of Boroecia maxima and Boroecia antipoda ( Muller , 1906 ) as subspecies of Boroecia borealis . - pubmed
Surgical procedures such as tumor resection and biopsy are still the gold standard for diagnosis and ( determination of ) treatment of solid tumors , and are prognostically beneficial for patients . - pubmed
This would allow precise stratification of high - risk patients requiring more aggressive treatment from low - risk ESCC patients who can forego radical surgery . - pubmed
INTRODUCTION : There is a major epidemic of obesity , and many obese patients suffer with respiratory symptoms and disease . - pubmed
After its introduction in clinical practice , the use of postsurgical radioiodine treatment was generalized to almost every patient with differentiated thyroid cancer , with the exception of unifocal microcarcinomas . - pubmed
Expert commentary : Although there is general consensus about the recommendation for very low - risk ( microcarcinomas ) and high - risk patients - no indication for routine postoperative radioiodine and clear indication for radioiodine treatment , respectively , the recommendation for low- and intermediate - risk patients is still under debate . - pubmed
We consider that these recommendations are in accordance with the best evidence available today , and we would like to emphasize that radioiodine is generally favored for most intermediate - risk patients , especially in the presence of extensive lymph node disease or older age . - pubmed
Diagnosis and Clinical Course of Three Adolescents with Amiodarone - Induced Hyperthyroidism . - pubmed
In the pediatric population , long - term amiodarone treatment is rarely indicated because of its severe side effects including thyroid function impairment . - pubmed
We present three adolescent patients developing amiodarone - induced thyrotoxicosis in the months after amiodarone therapy . - pubmed
A latency period for thyroid dysfunction has been described in adulthood but was not previously reported in pediatric patients . - pubmed
In two patients , hyperthyroidism was transient and resolved without treatment . - pubmed
In contrast , in one male patient overt and severe hyperthyroidism developed . - pubmed
Clinical evaluation proved an amiodarone - induced destructive thyroiditis in this patient . - pubmed
Amiodarone - induced thyroid dysfunction is frequent also in pediatric patients with long - term amiodarone treatment . - pubmed
Careful follow - up is needed , as symptoms might be associated with the underlying cardiac disease in these patients . - pubmed
In this study , we suggest that the creation of human - primate chimeras - specifically , the transfer of human stem cells into ( non - ape ) primate hosts - could not only surpass the limitations of current monkey models of neurological and psychiatric disease but would also raise important ethical considerations concerning the use of monkeys in invasive research . - pubmed
METHODS : Twenty - seven patients with aortic stenosis were included , 15 of whom underwent repeated imaging 4 weeks apart . - pubmed
Infection with Candida albicans can prove lethal in immuno - compromised patients . - pubmed
CRYPTOCOCCAL meningitis in a HIV negative newly diagnosed diabetic patient : a CASE report . - pubmed
BACKGROUND : This case report emphasizes the need to recognize cryptococcus as a possible cause of meningitis in non - HIV patients in Sub - Saharan Africa and to highlight the possibility of grave outcomes due to the paradoxical immune response in diabetic patients with cryptococcus meningitis . - pubmed
CONCLUSIONS : With the rising prevalence of diabetes in Sub - Saharan Africa , coupled with the low levels of adequate glucose control , cryptococcal meningitis should be considered in the differential diagnosis for diabetic patients presenting with chronic headache , fever and neurologic deficits . - pubmed
Cytoprotective agent for peptic ulcer prevention in patients taking dual antiplatelet agents : A randomized , double - blind placebo - controlled trial . - pubmed
BACKGROUND AND AIM : Long - term use of dual antiplatelets is increasing , and most patients need primary peptic ulcer prophylaxis . - pubmed
Patients receiving dual antiplatelets for & gt;= 1 year with no history of peptic ulcer bleeding or perforation were recruited and randomly assigned to the rebamipide ( 300 mg / day ) group or the placebo group . - pubmed
During the 12 months of follow up , 13 patients ( 43.3 % ) taking rebamipide and 19 ( 65.5 % ) taking the placebo experienced mucosal injury ( P = 0.07 ) . - pubmed
Two patients ( 6.7 % ) taking rebamipide and eight ( 27.6 % ) taking the placebo had peptic ulcers & gt;= 5 mm or & lt ; 5 mm with pigmented spots ( P = 0.03 ) . - pubmed
CONCLUSION : Rebamipide is safe and may prevent peptic ulcers & gt;= 5 mm in diameter or those with pigmented spots in patients receiving dual antiplatelets for 1 year ( NCT02166008 ) . - pubmed
OBJECTIVES : This study aimed to provide real - world data on the characteristics and treatment of patients with multiple myeloma ( MM ) at the time of death . - pubmed
CONCLUSIONS : These real - world data could be used to help develop strategies for improving survival in patients with MM and to support management tailored to the stage of disease . - pubmed
METHODS : Twenty - nine girls with adolescent idiopathic scoliosis formed the scoliotic group and 22 able - bodied girls formed the non - scoliotic group . - pubmed
PURPOSE : In patients with ICA stenosis , increased peak systolic velocity is a marker of stenosis at risk of ischemic stroke . - pubmed
METHODS : After review board approval , 15 healthy controls and 12 patients presenting ICA stenosis were explored with Doppler ultrasonography and 4DFlow MRI . - pubmed
This review aims to catch readers ' attention to the clinical diversity of phenotypes , differential diagnosis , and management of patients with FMF . - pubmed
Differential expression of miRNAs and their targets in wax - deficient rapeseed . - pubmed
Metabolic impact of pheochromocytoma / paraganglioma : Targeted metabolomics in patients before and after tumor removal . - pubmed
Patients with a noradrenergic tumor phenotype had more pronounced alterations compared to those with an adrenergic tumor phenotype . - pubmed
CONCLUSIONS : This first large prospective metabolomics analysis of PPGL patients demonstrates broad metabolic consequences of catecholamine excess . - pubmed
Robust impact on lipid and amino acid metabolism may contribute to increased morbidity of PPGL patients . - pubmed
METHODS : Sixteen patients presenting with symptomatic SICAD from September 2006 to October 2018 were reviewed retrospectively . - pubmed
Four patients received early intervention because of aneurysmal dilatation or distal hypoperfusion . - pubmed
Although collaterals prevented further hepatic ischaemia , one of these four patients failed in delayed intervention because of extensive thrombi completely occluding the hepatic artery . - pubmed
In the remaining eight patients who were managed conservatively , three ( 37.5 % ) showed regression of disease , one ( 12.5 % ) showed partial regression , and five ( 62.5 % ) showed no change in intimal flap or thrombosis , but all had symptomatic improvement . - pubmed
CONCLUSIONS : Early intervention in symptomatic SICAD patients may be necessary in over 50 % of patients , and endovascular stenting has durable long term outcomes . - pubmed
Burn wound infections and Pseudomonas aeruginosa . - pubmed
The treatment for the patients with Bankart lesion is the arthroscopic repair . - pubmed
a standard two anterior portals technique and a single anterior portal technique in patients with RDS . - pubmed
METHODS : Patients with traumatic RDS met the inclusion criteria were managed with Bankart repair using either two anterior portals ( Group A ) or a single anterior portal ( Group B ) technique . - pubmed
Serum vitamin K1 associated to microangiopathy and/or macroangiopathy in individuals with and without diabetes . - pubmed
However , difficult - to - cure / cirrhotic patients typically require a longer treatment duration and less is known regarding the long - term durability of SVR or effect on liver disease progression ; to assess this , the IMPACT study followed patients for a 3 - year period after end of treatment . - pubmed
A metabonomics and lipidomics based network pharmacology study of qi - tonifying effects of honey - processed Astragalus on spleen qi deficiency rats . - pubmed
Our previous study has demonstrated that honey - processed Astragalus exhibited a better effect on reinforcing qi ( vital energy ) and immune improvement toward spleen qi deficiency compared with radix Astragali . - pubmed
In this study , we evaluated the qi - tonifying effects of honey - processed Astragalus on spleen qi deficiency rats and predicted the mechanisms by aggregating metabonomics , lipidomics and network pharmacology . - pubmed
Therefore , to determine the role of MicroRNA-146a and MicroRNA-155 in MS patients , their expression levels in serum of MS patients were compared with healthy controls . - pubmed
In this study , the expression levels of MicroRNA-146a and MicroRNA-155 in 30 serum samples of MS and healthy patients as a control group . - pubmed
MicroRNA-146a and MicroRNA-155 levels were increased in patients with MS compared to controls . - pubmed
The initial survey determined the number of children with pBE . - pubmed
ABR abnormalities were present in 88 of 117 patients . - pubmed
A phase 2B randomised trial of hyperbaric oxygen therapy for ulcerative colitis patients hospitalised for moderate to severe flares . - pubmed
BACKGROUND : Hyperbaric oxygen has been reported to improve disease activity in hospitalised ulcerative colitis ( UC ) patients . - pubmed
METHODS : We enrolled UC patients hospitalised for acute flares ( Mayo score 6 - 12 ) . - pubmed
CONCLUSION : Hyperbaric oxygen appears to be effective for optimising response to intravenous steroids in UC patients hospitalised for acute flares , with low rates of re - hospitalisation or colectomy at 3 months . - pubmed
Association of Triglyceride Deposit Cardiomyovasculopathy With Drug - Eluting Stent Restenosis Among Patients With Diabetes . - pubmed
METHODS : This study included 162 HCM patients ( 61 % men ) who underwent septal myectomy . - pubmed
This study aims to introduce near - infrared spectroscopy analysis technology into the production process of fermented Cordyceps powder , including strain culture , strain passage , strain fermentation , strain filtration , strain drying , strain pulverizing , and strain mixing . - pubmed
A multi - omic study for uncovering molecular mechanisms associated with hyperammonemia - induced cerebellar function impairment in rats . - pubmed
Patients with liver cirrhosis may develop covert or minimal hepatic encephalopathy ( MHE ) . - pubmed
Rats with chronic HA show some motor and cognitive alterations reproducing neurological impairment in cirrhotic patients with MHE . - pubmed
Neuroinflammation and altered neurotransmission and signal transduction in the cerebellum from hyperammonemic ( HA ) rats are associated with motor and cognitive dysfunction , but underlying mechanisms are not completely known . - pubmed
The aim of this work was to use a multi - omic approach to study molecular alterations in the cerebellum from hyperammonemic rats to uncover new molecular mechanisms associated with hyperammonemia - induced cerebellar function impairment . - pubmed
In summary , this is a good approach to find altered pathways , which helps to describe the molecular mechanisms involved in the alteration of brain function in rats with chronic HA and to propose possible therapeutic targets to improve MHE symptoms . - pubmed
Inferring high - resolution human mixing patterns for disease modeling . - pubmed
The growing need for realism in addressing complex public health questions is , however , calling for accurate models of the human contact patterns that govern the disease transmission processes . - pubmed
Owners of 6/76 PER / EXO show cats stated that their cat had increased respiratory sounds and/or trouble breathing at least once a week . - pubmed
[ Determination of sero- and biovariants of foreign and Soviet strains of Yersinia enterocolitica ] . - pubmed
The results of the typing of the biochemical and serological variants of Yersinia enterocolitica strains from the USSR ( 10 strains ) and other countries ( 32 strains ) are presented . - pubmed
Malignant hepatomas induced in the rat by N - Nitrosomorpholine showed an absence of trisialogangliosides GT1 and , in some cases , also a decrease in disialoganglioside GD1a and monoganglioside GM1 . - pubmed
Effect of acid on the motility of the oesophagus of the pig with experimentally induced oesophagitis . - pubmed
The mucous membrane of the oesophagus of 6 pigs was experimentally damaged with hydrochloric acid to create changes similar to reflux oesophagitis . - pubmed
The passage of contrast medium through the oesophagus of the pigs was observed by using spot radiography and pressure measurements . - pubmed
The uptake of tryptophan and tyrosine by the brain has been studied in 6 manic - depressive patients and in 8 schizophrenics . - pubmed
Chloramphenicol is presently the drug of choice in the initial treatment of serious infections due to Hemophilus influenzae type b. - pubmed
A total of 160 strains of H. - pubmed
In tests conducted on mice and rats with transplantable tumours the antineoplastic activity of the racemic agent D , L-1,4 - dibromo-1 , 4 - didesoxy-2 , 3 - butandiol is shown . - pubmed
With chronic administration of the drug in subtherapeutic and therapeutic doses a higher leucocytes count was in evidence in the blood of the animals with and without tumours . - pubmed
Subcutaneous transplantation of EL4 lymphoma cells within C57BL10 mice evoked an oedematous inflammatory response involving increased leukopoiesis within the bone marrow , a blood leukocytosis , an influx of leukocytes into the transplants and surrounding host connective tissues , and extensive remodelling of surrounding host connective tissues involving fibroplasia and angiogenesis . - pubmed
Dexamethasone not only significantly reduced the numbers of circulating blood leukocytes within C57BL10 mice bearing the subcutaneous EL4 lymphoma transplants , but also reduced the oedematous inflammatory response to the transplants . - pubmed
The decreased influx of inflammatory leukocytes into the site of EL4 lymphoma cell transplantation within the dexamethasone - treated mice , was accompanied by reduced growth of the transplants . - pubmed
In a multicentre phase II trial , 20 patients with advanced pancreatic carcinoma were treated with 5 - fluorouracil , 4 - epidoxorubicin and mitomycin C , in which 4 - epidoxorubicin was administered by escalated dose and split course ( FEM II ) . - pubmed
In a prospective study 140 unselected patients with clinical evidence of benign adenoma of the prostate were resected via a transurethral approach . - pubmed
T0 tumors were found in 11.5 versus 5.2 % of the patients . - pubmed
Determination of basal tear turnover in insulin - dependent diabetes mellitus patients by fluorophotometry . - pubmed
The tear turnover was determined by fluorophotometry in 25 insulin - dependent diabetes mellitus ( IDDM ) patients without retinopathy and 29 IDDM patients with ( pre-)proliferative retinopathy . - pubmed
The results were compared with those in 34 healthy controls , to investigate the lacrimal gland function in diabetic patients . - pubmed
The tear turnover values in both patient groups did not correlate significantly with age or diabetes duration ( linear correlation coefficients : r less than 0.3 ) . - pubmed
The tear turnover values in patients both without retinoplathy and with ( pre-)proliferative retinopathy did not differ significantly from those in healthy controls ( mean + /- SD in % /min : 13.7 + /- 4.5 , 14.7 + /- 5.8 and 15.5 + /- 5.1 , respectively ; P greater than 0.16 ) . - pubmed
The tear turnover values correlated significantly with the HbA1c and Schirmer - test values in patients with ( pre-)proliferative retinopathy ( r = 0.7 and r = 0.4 , respectively ; P less than 0.02 ) and with the blood glucose values in patients without retinopathy ( r = 0.41 , P = 0.04 ) . - pubmed
Since the tear turnover was not significantly decreased in IDDM patients in comparison with healthy controls the corneal disorders which are more frequently seen in these patients than in a healthy population may not be attributed to a decrease in tear production . - pubmed
Workshop on the qualitative and quantitative comparability of human and animal developmental neurotoxicity : summary and implications . - pubmed
The Workshop on the Qualitative and Quantitative Comparability of Human and Animal Developmental Neurotoxicity was convened by the U.S. Environmental Protection Agency ( EPA ) and the National Institute on Drug Abuse to address issues related to when testing should be required , what test methodologies should be required , and how the data should be interpreted and applied to the risk assessment process . - pubmed
The background material for Work Group discussions included presentations made at the Workshop by invited experts summarizing qualitative and quantitative human and experimental animal data on specific chemicals or classes of chemicals and EPA 's proposed developmental neurotoxicity testing protocol . - pubmed
This overview : 1 ) summarizes the qualitative comparisons presented at the Workshop and attempts to make some quantitative comparisons of findings across mammalian species following exposure to developmental neurotoxicants , 2 ) brings the common themes that were discussed among the Work Groups together into a regulatory perspective , 3 ) provides a status report on EPA 's developmental neurotoxicity protocol , and 4 ) identifies research needs in the development of test methodologies and improvement of risk assessments for developmental neurotoxicants . - pubmed
Prevention of coccidiosis in the chukar partridge ( Alectoris chukar ) by medication with sulfadimethoxine and ormetoprim ( Rofenaid ) . - pubmed
Rofenaid ( a 5:3 mixture of sulfadimethoxine and ormetoprim ) was effective in preventing coccidiosis of chukar partridges . - pubmed
Rofenaid should , therefore , be an effective medication for the prevention of coccidiosis in chukars in the field . - pubmed
Oral sotalol was given to 64 patients ( 78 % postinfarction ) with recurrent , reentrant ventricular tachycardia ( VT ) during an average follow - up period of 19.7 months . - pubmed
Fifty - nine ( 92 % ) patients had previously experienced recurrent ventricular tachycardia , in spite of having received an average of three conventional antiarrhythmic drugs ( 13 had previously failed on other Class III drugs ) . - pubmed
Sotalol failed in five patients and was discontinued in six patients because of severe side effects ( three proarrhythmic effects , including two with torsades de pointes)--a total of 18 % . - pubmed
Dual chamber pacing was required by 11 patients because of poorly tolerated bradycardia , and 14 patients remained symptomatic from worsening of the cardiac failure in spite of pacing , increased diuretics , or vasodilator therapy . - pubmed
Impaired pump function in the patient with congestive heart failure can arise from both contraction ( inotropic ) and relaxation ( lusitropic ) abnormalities . - pubmed
The relative contributions of inotropic and lusitropic abnormalities to clinical disability differ in individual patients with heart failure , so that therapy of heart failure must be tailored to the specific pathophysiology that operates in each patient . - pubmed
A screening method aimed at identifying potential human carcinogens using either animal cancer bioassays or short - term genotoxic assays has 4 possible results : true positive , true negative , false positive and false negative . - pubmed
In 112 patients with symptoms from Paget ' s disease , 527 lesions were classified . - pubmed
Prolonged treatment with disodium etidronate led to progressive osteopenia in 11 patients . - pubmed
The UM - X7.1 myopathic and control hamsters at 40 , 120 and 280 days of age were employed for the examination of heart sarcolemmal Ca2 + -transport activities . - pubmed
Na +-dependent Ca2 + uptake activities were significantly depressed in myopathic animals at 120 and 280 days of age in comparison to the control values . - pubmed
It is suggested that a depression in the sarcolemmal Ca2 + transport activities may contribute to the development of intracellular Ca2 + overload in the genetically determined cardiomyopathy in hamsters and such a defect may be due to excessive amount circulating catecholamines in these animals . - pubmed
In vivo , the compounds produced variable hypocholesterolemic and/or hypotriglyceridemic effects when injected into groups of newly weaned rats fed standard chow , high fat or high carbohydrate diets . - pubmed
Lymphocytapheresis in a patient with severe aplastic anemia . - pubmed
A 17 - year - old Japanese boy with severe aplastic anemia was treated with oxymetholone and prednisolone for 9 weeks without improvement . - pubmed
There is considerable variation in the substitution rate among different genes , and the rate seems to be lower in nonhuman viral strains than in human strains . - pubmed
[ Autoradiographic study of the proliferative activity of bone marrow , spleen and liver cells in healthy mice and in mice with Rauscher virus - induced erythroleukemia ] . - pubmed
A variant of compensated cardiogenic shock occurring in patients with chronic congestive heart failure following an episode of pulmonary edema , and in the absence of hypotension , is described . - pubmed
In 55 patients with persistent sinus bradycardia who underwent an electrophysiologic study of sinus node , both in the basal state and after autonomic blockade ( propranolol , 0.2 mg / kg , and atropine , 0.04 mg / kg ) , an atropine test ( 0.02 mg / kg ) was performed the following day . - pubmed
These data evidence that the atropine test is not very helpful in discriminating between an organic and an autonomic involvement of sinus automaticity in patients with sinus bradycardia . - pubmed
Using special methods the authors examined the general sensitivity in clinically healthy pre - school children ( 5 - 7 years ) in comparison with the results of examination of clinically normal adults ( 18 - 20 years ) and patients with different levels and nature of foetal damage to the brain . - pubmed
for description of upper extremity function after stroke were compared by parallel assessments in a consecutive series of 50 patients with hemimotor deficit . - pubmed
Cephaloglycine as a urinary antimicrobial in patients with reduced renal function . - pubmed
Metabolic changes with exercise in patients with hypopituitarism . - pubmed
Circulating TGI has been observed in patient with " simple " goitre , Graves ' disease and more rarely in Hashimoto ' s thyroiditis . - pubmed
, LY104119 reduced the body weight of Avy / a mice without altering the food consumption . - pubmed
When slightly overweight a / a mice were treated with LY104119 in the diet , they lost weight , but a similar treatment of normal - weight a / a mice caused a loss of only a small amount of carcass triacylglycerol without affecting the body weight . - pubmed
Clot adherence to peritoneal cavity mesothelium was studied in rats in an attempt to contribute to the problem of thrombus embolization . - pubmed
Thirty patients ranging in age from 11 to 32 years were treated for acne or keratosis pilaris , using a new polyester sponge for facial epidermabrasion . - pubmed
Hemodynamic effects of sodium nitroprusside in patients with ventricular septal defect . - pubmed
During routine cardiac catheterization of ten patients with ventricular septal defect , the hemodynamic parameters were measured in the resting state and during sodium nitroprusside infusion at an average rate of 8 micrograms / kg / min . - pubmed
The favourable effect was most pronounced in patients who had pulmonary arterial hypertension in addition to elevated left ventricular filling pressures . - pubmed
Patients without pulmonary arterial hypertension showed an increase in the magnitude of left to right shunt . - pubmed
The present study strongly indicates the need for further investigations utilizing orally effective vasodilators in patients with congestive heart failure due to left to right shunts . - pubmed
Ion transport across the jejunum in normal and cystic fibrosis mice . - pubmed
Both the erbA IRES and the erbA / myb IRES virus constructs transformed erythroid cells after infection of bone marrow or blastoderm cultures . - pubmed
Surprisingly , when injected into chicken embryos in the presence of helper virus , both viruses induced an erythroleukemia in about half of the animals . - pubmed
The average latency of leukemia induction was shorter for the erbA / myb IRES virus ( 3.5 weeks ) than for the erbA IRES virus ( 5 weeks ) . - pubmed
Developmental arrest of fertilized eggs from the B6.YDOM sex - reversed female mouse . - pubmed
When the Y chromosome of a Mus musculus domesticus mouse strain is placed onto the C57BL/6J ( B6 ) inbred background , the XY progeny develop ovaries or ovotestes but never normal testes during fetal life . - pubmed
Between 1988 and 1990 , we examined fresh / frozen samples from 49 patients who had histologically confirmed adenocarcinomas of the bilio - pancreatic carrefour : They had 23 cancers of the pancreas , 21 of the Vater 's papilla , and 5 of the common bile duct . - pubmed
When the affected organ was considered , a statistically significant difference in survival was observed : At 88 wk , survival was 0 % for pancreatic and common bile duct cancer patients , and 18.2 % at 175 wk for Vater 's papilla cancer patients ( p = 0.04 ) . - pubmed
PURPOSE : Bronchioloalveolar cell adenomas ( BAAs ) have been described in up to 10 % of patients with bronchogenic carcinoma . - pubmed
METHODS : Follow - up information for a mean of 30 months was obtained on 28 patients with a single primary bronchogenic carcinoma and one or more coexistent BAAs . - pubmed
RESULTS : There was no significant difference between percentage survival of patients with a primary bronchogenic carcinoma and coexistent BAAs when compared with the percentage predicted survival of these patients based on their primary bronchogenic carcinoma alone . - pubmed
CONCLUSIONS : On standard preoperative imaging for bronchogenic carcinoma , BAAs were retrospectively detected in more than one third of patients in whom they were detected pathologically . - pubmed
UNLABELLED : We assessed the therapeutic benefits of 131I treatment in patients with distant metastases of differentiated thyroid carcinoma . - pubmed
METHODS : Of 2200 patients treated for differentiated thyroid carcinoma at our institution , 394 had lung and/or bone metastases . - pubmed
RESULTS : Two - thirds of the patients had 131I uptake in their metastases , but only 46 % achieved a complete response . - pubmed
The present study clearly demonstrates , however , that treatment with 131I is one of the factors which accounts for survival ; patients whose metastases concentrated 131I and who could be treated with radioiodine had higher survival rates . - pubmed
Other batches of silicone oil or paraffin oil permitted development from the zygote to the blastocyst of an outbred strain of mouse without arrest at the 2 - cell stage . - pubmed
This article reviews the effects of aging and hypertension on geometrical ( lumen and arterial wall thickness ) and functional ( distensibility ) properties of large and medium - sized arteries in humans . - pubmed
We report such an association in a 48 - year - old woman with several relatives suffering from MEN 2A. - pubmed
Treatment with topical capsaicin , which has been shown to be effective in notalgia paraesthetica , was not useful in our patient . - pubmed
The aim of the study was to quantify the presence in an abattoir and meat processing plant of risk factors represented by repetitive movements requiring the use of force , and to describe the work - related musculo - skeletal disorders ( WMSDs ) of the upper limbs found in a group of workers exposed to such risk factors . - pubmed
Intestinal complications were recorded and groups of animals were euthanized at 2 and 26 weeks to assess subacute and chronic injury . - pubmed
Extensive MR signal change in the craniad spinal cord parenchyma was found to be an ancillary sign of disease advancement in three patients with clinically progressive posttraumatic syringomyelia . - pubmed
Sensitivities of peptostreptococci , streptococci , Actinomyces , bacteroid , and fusobacterial strains pathogenic for the periodontium to wide - spectrum penicillines , cephalosporines , lincomycin , macrolides , metronidasole , and nitasole are compared . - pubmed
The mechanisms involved in mediating the enhanced gastric epithelial cell apoptosis observed during infection with Helicobacter pylori in vivo are unknown . - pubmed
In addition to stimulating apoptosis , infection with H. - pubmed
The failure to treat actinic keratoses may have serious consequences for the patient . - pubmed
Biologic variables in the outcome of stages I and II neuroblastoma treated with surgery as primary therapy : a children 's cancer group study . - pubmed
CONCLUSION : Children with stages I and II neuroblastoma have 98 % survival with surgery alone as primary therapy . - pubmed
Semiinvasive pulmonary aspergillosis in chronic obstructive pulmonary disease : radiologic and pathologic findings in nine patients . - pubmed
OBJECTIVE : The purpose of this study is to assess the radiographic , thin - section CT , and histologic findings of semiinvasive aspergillosis in patients with chronic obstructive pulmonary disease ( COPD ) . - pubmed
MATERIALS AND METHODS : The study included nine patients with COPD seen at the Hospital de Sant Pau during a 3 - year period who had histopathologically proven aspergillosis with tissue invasion . - pubmed
RESULTS : Nine patients had semiinvasive aspergillosis proven at autopsy ( n = 7 ) or by thoracoscopically guided lung biopsy ( n = 2 ) . - pubmed
Cavitation was present in two of the patients with consolidation and in two of the patients with nodular opacities . - pubmed
In the three patients with multiple cavitated nodules , a variable degree of central necrosis was observed . - pubmed
CONCLUSION : Upper lobe consolidation or multiple nodules in patients with COPD should raise the possibility of semiinvasive aspergillosis . - pubmed
[ Effect of diet therapy and increased physical activity on risk factors for atherosclerosis in obese patients with ischemic coronary heart disease ] . - pubmed
CONCLUSIONS : This study supports assumption that hypocaloric diet and physical training can improve outcome of patients with coronary heart disease by influencing risk factors of atherosclerosis . - pubmed
Daily interruption of sedative infusions in critically ill patients . - pubmed
Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse . - pubmed
PATIENTS AND METHODS : We report an open - label , uncontrolled , multicenter phase II trial of temozolomide in 138 patients ( intent - to - treat [ ITT ] population ) with glioblastoma multiforme at first relapse and a Karnofsky performance status ( KPS ) & gt ; or = 70 . - pubmed
One hundred twenty - eight patients were histologically confirmed with GBM or gliosarcoma ( GS ) by independent central review . - pubmed
CONCLUSIONS : Temozolomide demonstrated modest clinical efficacy , with an acceptable safety profile and measurable improvement in quality of life in patients with recurrent GBM . - pubmed
Selective norepinephrine reuptake inhibition as a human model of orthostatic intolerance . - pubmed
Vasovagal reactions occurred in 9 subjects on placebo and in 1 subject on reboxetine . - pubmed
This observation supports the hypothesis that disordered norepinephrine uptake mechanisms can contribute to human cardiovascular disease . - pubmed
UNLABELLED : Hepatitis C virus ( HCV ) has cytopathogenic effect not only on hepatocytes , however on salivary glands , monocytes of peripheral blood and lymphoid cells , may explain the systemic manifestations of the infection . - pubmed
HCV activates B and T - cells , modifies the immune response , causes lymphoproliferation , leading the development of B - cell non - Hodgkin ' s lymphoma ( NHL ) . - pubmed
PATIENTS AND METHODS : IgH gene rearrangements were examined from the sera of 57 chronic HCV infected patients and 11 HCV - positive cryoglobulinemic patients as well . - pubmed
CONCLUSIONS : These results support the hypothesis that IgH gene rearrangement in HCV positive patients can indicate the lymphoproliferative disorder in the HCV infection released B - cell proliferation and lymphoma development . - pubmed
An improved understanding of these mechanisms may be helpful in creating effective treatment programs for children with obesity . - pubmed
Hallucinations and delusions improved significantly in all patients . - pubmed
Donezepil was overall well tolerated , but a deterioration in motor disability was noted in 2 out of 8 patients . - pubmed
Univariate analysis indicated that there was a statistically significant difference in survival between the patients with alpha beta cutaneous T - cell lymphoma and patients with gamma delta cutaneous T - cell lymphoma ( P & lt;.0001 ) . - pubmed
Among those patients with cutaneous gamma delta T - cell lymphoma ( n = 33 ) , there was a trend for decreased survival for patients who had histologic evidence of subcutaneous fat involvement in comparison with patients who had epidermotropic or dermal patterns of infiltration ( P = .067 ) . - pubmed
To review and report our experience in eight patients with maxillofacial osteosarcomas , we retrospectively reviewed eight patients with high - grade maxillofacial osteosarcoma seen over the last decade at our institution . - pubmed
METHODS : Blood pressure responses to shifts in salt intake were measured in 274 individuals with essential hypertension in steady - state sodium balance on high ( 200 mEq ) and low ( 10 mEq ) sodium intakes . - pubmed
The aim of this study was to investigate the effects of DA-8159 on penile erection in conscious and acute spinal cord injured ( ASCI ) rabbits . - pubmed
RESULTS : DA-8159 induced a dose - dependent penile erection in both the conscious and ASCI rabbits . - pubmed
CONCLUSION : These results demonstrate that DA-8159 may be a useful treatment option for erectile dysfunction in patients with or without a spinal cord injury , but further evaluation of the effects of DA-8159 on humans must be performed . - pubmed
A retrospective chart review was performed on 130 patients from the Ohio State University Memory Disorders Clinic to examine the long - term effects of combination therapy with donepezil and vitamin E on patients with Alzheimer disease . - pubmed
Patients declined at a significantly lower rate as compared with the Consortium to Establish a Registry for Alzheimer ' s Disease data . - pubmed
The long - term combination therapy of donepezil and vitamin E appears beneficial for patients with Alzheimer disease . - pubmed
OBJECTIVES : To illuminate the current methodological and conceptual pitfalls inherent in conducting functional magnetic resonance imaging ( fMRI ) research with individuals who have sustained traumatic brain injury ( TBI ) and to discuss appropriate remedies . - pubmed
We present the unusual occurrence of multiple systemic and two central nervous system tuberculomas in an immunocompetent young patient . - pubmed
Cultures of the specimens yielded a mixed infection with Corynebacterium species and Staphylococcus epidermidis . - pubmed
One of the hallmarks of patients with glioblastoma multiforme ( GBM ) is profound lymphopenia mostly confined to the T cell lineage . - pubmed
A deficiency in the production of naive T cells from the thymus could contribute to the lymphopenia seen in GBM patients . - pubmed
Detection of Trypanosoma cruzi and Trypanosoma rangeli infection by duplex PCR assay based on telomeric sequences . - pubmed
A 57 - year - old woman was admitted because of severe bradycardia and hypotension caused by an anti - arrhythmic agent and beta - blocker . - pubmed
RESULTS : A male patient , white , 2 years - old , suffered multiple stings of small red ants of the species Solenopsis invictas , with the occurrence of severe anaphylactic reactions , and resulting in cortical blindness as a neurological sequel . - pubmed
Vascular calcification is highly correlated with cardiovascular disease ( CVD ) and is a significant predictor of cardiovascular events , especially in high risk patients such as the end stage renal disease ( ESRD ) population . - pubmed
MATERIALS AND METHODS : A comprehensive number of four operators from 3 hospitals evaluated 57 consecutive patients with 60 focal hepatic lesions ( 28 hepatocellular carcinomas , 11 metastases , 13 hemangiomas , 1 hepatocellular adenoma and 7 focal nodular hyperplasias ) by baseline gray - scale ultrasound ( US ) and color Doppler US . - pubmed
Making a pre - operative diagnosis allows the neurosurgeon to be confident in the choice of treatment plan for the patient and allays considerable patient anxiety . - pubmed
[ Out - of - body experience as possible seizure symptom in a patient with a right parietal lesion ] . - pubmed
We report a 44 - year - old patient with epigastric auras , psychomotor and grand mal seizures , and paroxysmal experiences during which he believed to have left his body and seen himself from the outside . - pubmed
Following extirpation of the lesion , the patient has been seizure - free for 5 years . - pubmed
A meta - analysis of the relationship of child sexual abuse to HIV risk behavior among women . - pubmed
OBJECTIVE : This study is a meta - analysis of the literature exploring the relationship between child sexual abuse ( CSA ) and HIV risk behavior among women . - pubmed
Persistent high - level BKV replication is the hallmark of polyomavirus - associated nephropathy in renal transplantation and of hemorrhagic cystitis in bone marrow transplantation . - pubmed
The role of BKV in autoimmune disease and cancer is a controversial topic and is difficult to determine , because the pathology no longer depends on BKV replication . - pubmed
We reviewed our experience to investigate the determinants of paraplegia after stent - graft repair of the thoracic aorta , identify patients at risk , and assess the effectiveness of ancillary techniques . - pubmed
Indications for treatment were atherosclerotic aneurysms in 88 patients , chronic type B dissection in 10 patients , and penetrating aortic ulcer in 5 patients . - pubmed
Four of the 103 patients affected with thoracoabdominal aortic aneurysms had hybrid procedures and were excluded from the cumulative analysis . - pubmed
Twelve patients with zone 0 and zone 1 aortic arch aneurysms were operated on with synchronous or staged surgical aortic debranching . - pubmed
Neurologic deficits were assessed by an independent neurologist and classified as immediate or delayed . - pubmed
Four patients ( 4.04 % ) had delayed neurologic deficit that completely resolved after the institution of CSF drainage , steroids administration , and arterial pressure pharmacologic adjustment . - pubmed
None of the four patients who underwent hybrid procedures for thoracoabdominal aortic aneurysms had paraplegia or paraparesis . - pubmed
Percentage of hepatitis C virus - infected hepatocytes is a better predictor of response than serum viremia levels . - pubmed
An integrated analysis of thirteen trials summarizing the long - term safety of alefacept in psoriasis patients who have received up to nine courses of therapy . - pubmed
OBJECTIVE : The aim of this work was to further examine the safety profile of alefacept by integrating data from clinical trials involving patients with chronic plaque psoriasis who received up to 9 courses of therapy over a 5 - year period . - pubmed
METHODS : Data from 13 clinical trials conducted in patients with plaque psoriasis were integrated because they had similar inclusion / exclusion criteria and assessments . - pubmed
CONCLUSIONS : This integrated analysis of data from 13 trials with 1869 patients supports the safety and tolerability of alefacept for longer - term treatment of psoriasis . - pubmed
According to the last IKDC evaluation , 7 patients ( 58.33 % ) were graded A , 4 patients ( 33.3 % ) B , and 1 patient ( 8.33 % ) C. Except for 1 patient who complained of mild pain at the donor site of the contralateral healthy knee , no patients complained of donor - site morbidity or dysfunction of the healthy leg . - pubmed
Because inclusion of PCB - contaminated fish , which comprised approximately 1 % of the diet , resulted in mandibular and maxillary squamous cell proliferation , it is possible that consumption of up to 30 - fold that quantity of HR fish , as could be expected for wild mink , would result in more severe lesions characterized by loss of teeth , thus impacting survivability . - pubmed
[ Long - term effects of early hyperbaric oxygen therapy on neonatal rats with hypoxic - ischemic brain damage ] . - pubmed
This study was designed to evaluate the long - term pathological and behavioral changes of early HBO therapy on neonatal rats with HIBD . - pubmed
RESULTS : The rats in the HIBD group displayed significant morphological and histological deficits , as well as severe spatial learning and memory disability . - pubmed
RESULTS : Among 637 patients with biopsy - proven GN included in this study , 88 ( 13.8 % ) had glomerular crescent formation . - pubmed
Among them , pauci - immune crescentic glomerulonephritis ( PICGN ) ( 42 patients , 47.2 % ) and lupus nephritis ( 25 patients , 28.4 % ) were the most common pathologic diagnoses . - pubmed
Lupus patients were younger ( p = 0.028 ) , while PICGN patients had more chronic lesions ( p & lt ; 0.001 ) , extensive glomerular crescents ( p & lt ; 0.001 ) , less severe proteinuria ( p & lt ; 0.001 ) and poorer renal survival ( p = 0.0017 ) . - pubmed
When injected into newborn mice , the glutamatergic analogue , ibotenate , produces cortical lesions and white matter cysts that mimic human perinatal brain lesions . - pubmed
This is true for both herpes simplex virus type-1 and herpes simplex virus type-2 . - pubmed
Seizure prophylaxis in an animal model of epilepsy by dietary fluoxetine supplementation . - pubmed
The present studies tested the possibility that the El mouse model of genetically predisposed / handling - triggered epilepsy would exhibit fewer seizures following SSRI treatment via dietary fluoxetine adulteration . - pubmed
El mice consuming a chow diet ad libitum or yoked in quantity to fluoxetine diet intake exhibited seizure incidence of 40 % in response to tail - suspension handling , whereas seizures were abolished ( 0 % ) among El mice consuming a fluoxetine - adultered diet over 7 days . - pubmed
Taken together , these results suggest that dietary fluoxetine supplementation abolishes handling - induced seizure susceptibility in El mice via a neural remodeling mechanism independent of energy balance . - pubmed
METHODS : CCl4 , 0.5 mL / kg body weight , was injected into the peritoneum of C57BL/6 mice twice a week for 5 wk . - pubmed
Although very few ES - derived cells were demonstrated immunohistologically in the livers of group 1 mice on PD 30 , improvements in liver fibrosis were observed . - pubmed
Unexpectedly , liver tumor formation was not observed in any of the mice that received ES cell transplantation during the experimental period . - pubmed
An intervention for manic or mixed symptomatology was required in 27 patients , whereas 22 patients were treated for depressive symptoms . - pubmed
OBJECTIVE : To estimate the prevalence of the hepatitis C virus ( HCV ) and HIV infection and associated risk behaviors among injection drug users ( IDUs ) in two northern Mexican cities . - pubmed
Batrachochytrium dendrobatidis infection was identified in 64 % of the R. - pubmed
sphenocephala larvae might be resistant to infection , even when occupying the same wetland as the infected R. - pubmed
Kidney transplantation is the treatment of choice for patients with ESRD . - pubmed
Other factors , including cardiovascular disease , infections , and malignancies , also shorten patient survival and therefore reduce the functional life of an allograft . - pubmed
Therefore , interventions need to address disease progression , comorbid conditions , and patient mortality through a multifaceted approach . - pubmed
In the last 25 years , human immunodeficiency virus ( HIV ) has become the leading infectious killer of adults globally , with an estimated 44 million people infected with the virus worldwide . - pubmed
Evaluation of the need for endoscopy to identify low - risk patients presenting with an acute upper gastrointestinal bleed suitable for early discharge . - pubmed
METHODS : All patients with low - risk acute upper GI bleeding presenting to two separate hospital sites in Leeds from August 2002 to March 2005 were identified . - pubmed
None of the 194 patients had further bleeding or complications within 30 days . - pubmed
CONCLUSIONS : Patients admitted with a low - risk acute upper GI bleeding can be managed safely by a nurse - led process - driven protocol , based on readily available clinical and laboratory variables , with early discharge & lt;24 h. Avoiding in - patient endoscopy appears to be safe but at the price of greater clinic follow - up . - pubmed
Sleeping hearts : the role of the heart in sleeping sickness ( human African trypanosomiasis ) . - pubmed
OBJECTIVES : To estimate the frequency and evolution of heart involvement in human African trypanosomiasis ( HAT ) using electrocardiogram ( ECG ) findings ; to describe these findings and to assess the frequency and clinical relevance of symptoms and signs before and after treatment . - pubmed
RESULTS : Major ECG alterations were significantly more frequent in HAT patients than in healthy controls ( 71%vs . - pubmed
The median NT - proBNP was significantly higher in HAT patients than in controls ( 85.2 vs. 28 pg / ml ; P & lt ; 0.001 ) . - pubmed
CONCLUSIONS : Cardiac involvement documented by ECG alterations is common in HAT patients , but cardiopathy rarely causes severe congestive heart failure and subsides after treatment . - pubmed
Electromyographic characterization in an animal model of dystonia . - pubmed
Kernicterus is known to produce damage to the auditory system and the basal ganglia in humans . - pubmed
Although the Gunn rat model of kernicterus has been extensively used to characterize the auditory features , this model has not been similarly utilized to systematically investigate the movement disorder . - pubmed
In the present study , spontaneously jaundiced ( jj ) 16 day old Gunn rat pups were treated with sulfadimethoxine to exacerbate bilirubin toxicity and compared to saline treated jjs and non - jaundiced ( Nj ) littermates . - pubmed
Electromyographic ( EMG ) activity was recorded from antagonistic hip muscles in dystonic and in normal appearing rats . - pubmed
Coherence plots of the separated signals coefficients revealed 4 - 7 Hz co - activation in antagonistic muscles that was significantly more prominent in jj sulfa treated dystonic compared to normal rats . - pubmed
The EMG findings support the presence of dystonia in sulfadimethoxine exposed jj Gunn rats and suggest that these animals can serve as a valuable model for experimental investigations of dystonia . - pubmed
DBDCT exhibited strong in vitro cytotoxic activity toward human immature granulocyte leukemia ( HL-60 ) , human salivary - gland carcinoma ( SGC-7901 ) , human henrietta carcinoma ( Hela ) and human urinary bladder ( T24 ) cell lines which , in some cases , were equal to , or even higher than those of cis - dichlorodiammineplatinum ( II ) ( cisplatin , DDP ) , the widely clinically used drug . - pubmed
The further in vivo antitumor tests of DBDCT towards the transplantation tumor models of sarcoma carcinoma ( S(180 ) ) , hepatocellular carcinoma ( H(22 ) ) and Ehrlich 's ascites carcinoma ( EAC ) on mice were carried out via injection intraperitoneally with cisplatin as positive contrast drug . - pubmed
RESULTS : Group C had significantly fewer patients with biliary tract disease , improper diet and heavy alcohol consumption , and significantly more patients with passed history of moderate - severe hypertriglyceridemia than Group A and B ( P & lt ; 0.05 ) . - pubmed
PSD increased the susceptibility of mice to LPS - induced immobility in the open field , which was capable of affecting the anxiety - like behavior also . - pubmed
Injection of non - specific dsRNA initiates a broad - spectrum innate antiviral immune response in the Pacific white shrimp , Litopenaeus vannamei , however , the receptor involved in recognition of this by - product of viral infections remains unknown . - pubmed
Furthermore , several experimental studies have shown that NTDs in embryos of diabetic mice are associated with altered expression of genes , which control development of the neural tube . - pubmed
Double - blind , placebo - controlled study to evaluate two miconazole conditioners for the treatment of Malassezia dermatitis in dogs . - pubmed
Eighteen dogs with Malassezia dermatitis participated in a clinical trial to evaluate the efficacy of miconazole conditioners . - pubmed
Investigators evaluated erythema , pruritus , and yeast counts weekly . - pubmed
However , MMC mice on the C3H background were susceptible to arthritis also with a functional oxidative burst . - pubmed
BACKGROUND : The purpose of this study was to assess the efficacy and toxicity of biweekly irinotecan plus 5 - fluorouracil ( FU ) and leucovorin ( LV ) in patients with relapsed or metastatic colorectal cancer . - pubmed
MATERIALS AND METHODS : Between March 2002 and May 2004 , 24 patients with histologically confirmed relapsed or metastatic colorectal cancer were enrolled in this study . - pubmed
CONCLUSION : The results suggested that irinotecan , 5 - FU and leucovorin combination chemotherapy in a biweekly schedule is a practical and tolerable treatment option in patients with advanced colorectal cancer . - pubmed
OBJECTIVE : To assess treatments and survival of patients with muscle invasive bladder cancer ( MIBC ) in the Comprehensive Cancer Center Northern Netherlands ( CCCN ) region . - pubmed
A patient presented with a superior sulcus tumor situated anterior in the thoracic inlet . - pubmed
Quality of life in patients with vitiligo : a descriptive study on 83 patients attending a PUVA therapy unit in Imam Reza Hospital , Mashad . - pubmed
BACKGROUND : Several meta - analyses indicate that there is an inverse genetic correlation between ethanol preference drinking and ethanol withdrawal severity , but limited work has characterized ethanol consumption in 1 genetic animal model , the Withdrawal Seizure - Prone ( WSP ) and - Resistant ( WSR ) mouse lines selected for severe or mild ethanol withdrawal , respectively . - pubmed
RESULTS : Withdrawal Seizure - Prone-1 mice consumed more ethanol than WSR-1 mice under a fixed ratio ( FR)-4 schedule as ethanol was faded into the sucrose solution , but this line difference dissipated as the sucrose was faded out to yield an unadulterated 10 % v / v ethanol solution . - pubmed
OBJECTIVE : To evaluate the clinical characteristics of oropharyngeal dysphagia in Machado - Joseph disease patients . - pubmed
METHOD : Forty individuals participated in this study , including 20 with no clinical complaints and 20 dysphagic patients with Machado - Joseph disease of clinical type 1 , who were all similar in terms of gender distribution , average age , and cognitive function . - pubmed
At the end , the profile of dysphagia in patients with Machado - Joseph disease was classified according to the Severity Scale of Dysphagia , as described by O'Neil and collaborators . - pubmed
RESULTS : Comparison between dysphagic patients and controls did not reveal many significant differences with respect to the clinical evaluation of the oral phase of deglutition , since afflicted patients only demonstrated deficits related to the protrusion , retraction and tonus of the tongue . - pubmed
Dysphagic patients presented pharyngeal stasis during deglutition of liquids and solids , accompanied by coughing and/or choking as well as penetration and/or aspiration ; these signs were absent in the controls . - pubmed
The dysphagia of these patients is classified between mild and moderate . - pubmed
METHODS : Eight patients ( three males and five females ) with stable vitiligo qualified for the study . - pubmed
CONCLUSIONS : Autologous minigrafts with ultrapulsed carbon dioxide laser abrasion appear to have the potential to achieve complete repigmentation in patients with stable vitiligo who fail to respond to medical treatments . - pubmed
Therapeutic benefit of Yangxue Qingnao Granule on cognitive impairment induced by chronic cerebral hypoperfusion in rats . - pubmed
METHODS : Adult male Wistar rats were subjected to chronic cerebral hypoperfusion by permanent occlusion of bilateral common carotid arteries ( 2 - VO ) . - pubmed
Nicotinamide treatment protects pups against intestinal injury incurred in the newborn rat NEC model . - pubmed
Previous studies have shown a protective effect of glycine on this toxicity in rat hepatocytes ( Vance et al . - pubmed
In the present study we investigated the hepatoxicity of 1 - 4 mM valproate in combination with glycine through absorption of neutral red from human hepatoma cells ( Hep G2 ) in monolayer cell culture . - pubmed
In conclusion a hepatoprotective effect of glycine on valproate - induced toxicity is also given in human hepatocytes . - pubmed
Analysis of gut morphogenesis in Shroom3 deficient mouse embryos revealed that the direction of gut rotation is also disrupted . - pubmed
A number of animal experiments have explored both acute and long - term toxicity with respect to the lungs , the cardiovascular system , and the bladder , showing inflammatory and possible carcinogenic effects . - pubmed
Affected individuals often show a unique pattern of cognitive strengths and weaknesses and are at increased risk for a number of other neurodevelopmental conditions , many of which are more common in typical males than typical females ( e.g. - pubmed
Understanding the contribution of these different mechanisms to outcome has the potential to improve clinical care for individuals with TS and to better our understanding of the differential vulnerability to and expression of neurodevelopmental disorders in males and females . - pubmed
In this paper , we review what is currently known about cognition and brain development in individuals with TS , discuss underlying mechanisms and their relevance to understanding male - biased neurodevelopmental conditions , and suggest directions for future research . - pubmed
Thus the EBV - positive HL could in the future prove to be an excellent candidate for targeted cellular immunotherapy . - pubmed
Minor hepatic resection for hepatocellular carcinoma in cirrhotic patients : Kelly clamp crushing resection versus heat coagulative necrosis with bipolar radiofrequency device . - pubmed
Hemorrhage and postoperative liver insufficiency are frequent and serious complications of hepatic resection in cirrhotic patients . - pubmed
We retrospectively reviewed the results of 35 patients who had undergone resection for monofocal hepatocellular carcinoma at our center . - pubmed
This nonrandomized retrospective study suggests that radiofrequency - assisted liver resection is associated with better results than the Kelly clamp crushing resection technique in cirrhotic patients with focal hepatocellular carcinoma and preserved liver function . - pubmed
BACKGROUND : High levels of viable Staphylococcus aureus , which are often found on inflamed skin surfaces , are usually associated with atopic dermatitis . - pubmed
No associations between levels of viral diversity within the non - structural genes and HIV-1 RNA load during primary infection were found . - pubmed
Effect of carvedilol and nebivolol on oxidative stress - related parameters and endothelial function in patients with essential hypertension . - pubmed
Vittatidera zeaphila ( Nematoda : Heteroderidae ) , a new genus and species of cyst nematode parasitic on corn ( Zea mays ) . - pubmed
Intravenous administration of human umbilical cord blood - mononuclear cells dose - dependently relieve neurologic deficits in rat intracerebral hemorrhage model . - pubmed
Intravenously transplanted UC - MCs can accelerate the neurological function recovery of ICH rat and diminish the striatum lesion size by demonstrating a dose relationship between them . - pubmed
Hemiarthroplasty for humeral four - part fractures for patients 65 years and older : a randomized controlled trial . - pubmed
QUESTIONS / PURPOSES : We therefore performed a randomized controlled trial to compare ( 1 ) function , ( 2 ) strength , and ( 3 ) pain and disability in patients 65 years and older with four - part humeral fractures treated either nonoperatively or with hemiarthroplasty . - pubmed
Abduction strength was better at 3 and 12 months in the nonoperatively treated group although the nonoperatively treated patients experienced more pain at 3 months ; this difference could not be detected after 12 months . - pubmed
CONCLUSIONS : We observed no clear benefits in treating patients 65 years or older with four - part fractures of the proximal humerus with either hemiarthroplasty or nonoperative treatment . - pubmed
BACKGROUND : There are limited data comparing radiofrequency catheter ablation with antiarrhythmic drug therapy as first - line treatment in patients with paroxysmal atrial fibrillation . - pubmed
METHODS : We randomly assigned 294 patients with paroxysmal atrial fibrillation and no history of antiarrhythmic drug use to an initial treatment strategy of either radiofrequency catheter ablation ( 146 patients ) or therapy with class IC or class III antiarrhythmic agents ( 148 patients ) . - pubmed
At 24 months , the burden of atrial fibrillation was significantly lower in the ablation group than in the drug - therapy group ( 90th percentile , 9 % vs. 18 % ; P=0.007 ) , and more patients in the ablation group were free from any atrial fibrillation ( 85 % vs. 71 % , P=0.004 ) and from symptomatic atrial fibrillation ( 93 % vs. 84 % , P=0.01 ) . - pubmed
CONCLUSIONS : In comparing radiofrequency ablation with antiarrhythmic drug therapy as first - line treatment in patients with paroxysmal atrial fibrillation , we found no significant difference between the treatment groups in the cumulative burden of atrial fibrillation over a period of 2 years . - pubmed
METHODS : Twenty consecutive patients treated by volar locking plate fixation for low - grade open DRFs constituted the open fracture group , and 40 patients were selected from among the total number of patients treated by volar , locking plate fixation for closed DRFs as the closed fracture group . - pubmed
Recurrent SAH was defined as two or more discrete episodes of SAH ( discriminant function>=32 ) coinciding with recidivism in the same patient , with documented improvement / resolution of jaundice during intervening periods of abstinence . - pubmed
RESULTS : Of 56 patients with recidivism following index presentation with SAH , 10 ( 17.9 % ) developed recurrent SAH . - pubmed
CONCLUSION : Approximately 18 % of patients , especially women , develop recurrent SAH because of recidivism , with increasing disease severity and mortality approaching 60 % . - pubmed
METHODOLOGY AND RESULTS : In our modified rat model of NIC , a trapezoid - shaped silicon rubber was inserted into the epidural space under the L5 and L6 vertebral plate . - pubmed
vulgaris infection and simultaneous occurrence of Strongylus edentatus and Triodontophorus spp . - pubmed
Vertebral augmentation in patients with multiple myeloma : a pooled analysis of published case series . - pubmed
BACKGROUND AND PURPOSE : Studies examining the efficacy of vertebroplasty and kyphoplasty in patients with vertebral fractures from multiple myeloma are limited . - pubmed
We sought to perform a systematic review of published case studies examining changes in pain , disability , and analgesic drug use in patients with multiple myeloma who have undergone vertebral augmentation . - pubmed
MATERIALS AND METHODS : We performed a pooled analysis of published case series of vertebral augmentation in patients with multiple myeloma . - pubmed
RESULTS : Patients achieved a decrease in pain across all consolidated time periods . - pubmed
CONCLUSIONS : Our analysis demonstrates that vertebral augmentation is effective in patients with multiple myeloma . - pubmed
Audiologic and vestibular assessment in patients with beta - thalassemia major receiving long - term transfusion therapy . - pubmed
BACKGROUND : Life - long transfusion therapy with chelators is a treatment choice for patients with beta - thalassemia major . - pubmed
PROCEDURE : Thirty - seven patients with beta - thalassemia major who received regular transfusion in our hospital were enrolled . - pubmed
Sixteen patients ( 80 % ) had canal paresis in the caloric test . - pubmed
CONCLUSIONS : The incidence of auditory impairment and vestibular dysfunction was high in patients with beta - thalassemia major receiving long - term transfusion therapy . - pubmed
Since then , 12 patients with AA have been treated with TG . - pubmed
Here , we summarize the effectiveness and safety of TG in comparison with data from 14 AA patients treated with LG before April 2009 . - pubmed
Infection was noted in five ( 38 % ) and four ( 33 % ) subjects treated with LG and TG , respectively . - pubmed
We conclude that TG at a dose of 2.5 mg / kg / day for 5 days is effective and safe in Japanese patients with AA . - pubmed
44 healthy volunteers free from postural and temporomandibular disorders . - pubmed
Low - frequency , Repetitive Transcranial Magnetic Stimulation for the Treatment of Patients with Posttraumatic Stress Disorder : a Double - blind , Sham - controlled Study . - pubmed
The aim of this study was to compare the effect of rTMS on the right prefrontal cortex with that of sham stimulation among patients with PTSD . - pubmed
METHODS : In total , 18 patients with PTSD were randomly assigned to the 1 - Hz low - frequency rTMS group or the sham group for 3 weeks . - pubmed
Association of 25 - hydroxyvitamin D serum levels and metabolic parameters in psoriatic patients with and without arthritis . - pubmed
OBJECTIVE : The objective was to assess the relationship of 25 - hydroxyvitamin D [ 25 -( OH ) D ] levels with lipid and glucose metabolism parameters in psoriatic patients with and without arthritis . - pubmed
METHODS : We studied 122 patients with psoriasis ( 61 without arthritis and 61 with arthritis ) from the psoriasis unit ( dermatology department ) and rheumatology department of our hospital , analyzing lipid and glucose metabolism variables and serum 25 -( OH ) D concentrations . - pubmed
No association was found between serum 25 -( OH ) D levels and any metabolic parameter in the patients with psoriatic arthritis . - pubmed
CONCLUSIONS : Serum 25 -( OH ) D was inversely related to lipid and glucose metabolism parameters in psoriatic patients without arthritis , whereas no such association was observed in psoriatic patients with arthritis . - pubmed
Interventional studies are warranted to assess the effects of vitamin - D supplements on the metabolic profile of psoriatic patients without arthritis . - pubmed
Effects of MLC601 on early vascular events in patients after stroke : the CHIMES study . - pubmed
A complex odontoma of the anterior maxilla associated with an erupting canine . - pubmed
We outline a list of major issues and also suggest some standardized procedures in collecting clinical and imaging data on major depressed patients . - pubmed
The authors describe the case of a 31 - year - old woman presenting with low - back and radicular pain without weakness or bowel or bladder dysfunction . - pubmed
BACKGROUND / AIMS : Bacterial translocation ( BT ) promotes microinflammation in predialysis patients with end - stage renal disease ( ESRD ) . - pubmed
However , the change in BT has not been reported in ESRD patients undergoing regular hemodialysis treatment . - pubmed
METHODS : A prospective study was carried out in which adult HIV-1 - infected patients who started mtDRV / rtv after viral suppression for & gt;= 6 months with no major darunavir - related resistance mutations were enrolled . - pubmed
Patients with two consecutive plasma HIV RNA measurements & gt;200 HIV-1 RNA copies / mL were considered as having virological failure ( VF ) , while patients with two consecutive plasma HIV RNA measurements & gt;50 copies / mL without meeting the VF criteria were considered to have virological rebound ( VR ) . - pubmed
Serum 8,12 - iso - iPF2alpha - VI isoprostane marker of oxidative damage and cognition deficits in children with konzo . - pubmed
We sought to determine whether motor and cognitive deficits associated with cassava ( food ) cyanogenic poisoning were associated with high concentrations of F2 - isoprostanes , well - established indicators of oxidative damage . - pubmed
These findings suggest that cognitive deficits and , possibly , brain injury associated with cassava poisoning is mediated in part by oxidative damage in children with konzo . - pubmed
8,12 - iso - iPF2alpha - VI isoprostane appears to be a good marker of the neuropathogenic mechanisms of konzo and may be used to monitor the impact of interventional trials to prevent the neurotoxic effects of cassava cyanogenic poisoning . - pubmed
Histoplasmosis caused by Histoplasma capsulatum var . - pubmed
OBJECTIVE : Study of pulmonary hypertension ( PAH ) during pregnancy has characteristics of the high risk factors for patient death and its clinical characteristics . - pubmed
RESULTS : ( 1 ) In 8 patients , 4 cases were IPAH , none of them with primary diseases , and they were complicated with severe tricuspid regurgitation . - pubmed
(4 ) In 8 patients , 7 cases of median death time were 3 days after delivery , including 4 cases of IPAH patients death for 2.5 days after delivery ; the causes of death were PAH crisis and heart failure . - pubmed
( 5 ) In 8 patients , 1 patient with CHD - PAH secondary to patent ductus arteriosus in gestational week 31 stillbirths occur . - pubmed
( 2 ) Compared with the pregnant women with CHD- PAH , faster progress and poor prognosis in patients with IPAH disease . - pubmed
( 3)The patients during cesarean operation or intrapartumare easy to cause PAH crisis and heart failure or multiple organ failure . - pubmed
Taking active measures to maintain stability of hemodynamics is the key to prevent the occurrence of death of pregnant women with PAH . - pubmed
Chronic phalaris toxicity in eastern grey kangaroos ( Macropus giganteus ) . - pubmed
Zinc supplementation suppresses the progression of bile duct ligation - induced liver fibrosis in mice . - pubmed
Hydrogen peroxide administered into the rat spinal cord at the level elevated by contusion spinal cord injury oxidizes proteins , DNA and membrane phospholipids , and induces cell death : attenuation by a metalloporphyrin . - pubmed
H2O2 was perfused through a microcannula into the uninjured rat spinal cord to mimic the conditions induced by SCI . - pubmed
Lithium remains the first line for the treatment and prophylaxis of bipolar disorders , but currently available treatment alternatives for lithium resistant patients are of limited and/or questionable efficacy . - pubmed
, a mania followed by a depression , in rats . - pubmed
In this study , we examined the innate immune potential of primary LEC populations derived from multiple tissues of an animal model for human infectious diseases - the ferret . - pubmed
MATERIALS AND METHODS : This study is a retrospective chart review , and in this study , hospital records of 58 patients with biopsy proven sinonasal malignancies were studied . - pubmed
Impaired right ventricular hemodynamics indicate preclinical pulmonary hypertension in patients with metabolic syndrome . - pubmed
The contributions of metabolic syndrome ( MetS ) and obesity to pulmonary hypertension and right ventricular dysfunction in humans remain unclear . - pubmed
We investigated the association of MetS and obesity with right ventricular structure and function in patients without cardiovascular disease . - pubmed
METHODS AND RESULTS : A total of 156 patients with MetS ( mean age 44 years , 71 % women , mean body mass index 40 kg / m(2 ) ) , 45 similarly obese persons without MetS , and 45 nonobese controls underwent echocardiography , including pulsed wave Doppler measurement of pulmonary artery acceleration time ( PAAT ) and ejection time . - pubmed
Hydrochlorothiazide - induced tubulointerstitial nephritis in a patient with Dent disease . - pubmed
Coagulase negative staphylococci and Enterobacteriaceae are the most frequent pathogens causing approximately 25 % of BSI each , followed by enterococci , P. - pubmed
Weight change during long - term treatment with lurasidone : pooled analysis of studies in patients with schizophrenia . - pubmed
The objective of this analysis was to evaluate the effect of 12 months of treatment with lurasidone on weight in patients with schizophrenia . - pubmed
Weight gain of at least 7 % from study baseline was observed in 16.0 , 25.8 , and 15.2 % of patients , and weight loss of at least 7 % was seen in 18.5 , 6.7 , and 9.1 % of patients treated with lurasidone , risperidone , and quetiapine XR , respectively . - pubmed
A shift from normal / underweight baseline BMI status to overweight / obese at month 12 occurred in 10.2 , 27.6 , and 15.0 % of patients in the lurasidone , risperidone , and quetiapine XR groups , respectively . - pubmed
Conversely , 14.3 , 1.7 , and 7.7 % of patients , respectively , shifted from overweight / obese to normal / underweight . - pubmed
In summary , a low potential for clinically significant weight gain was observed in patients with schizophrenia treated continuously with lurasidone for 12 months . - pubmed
METHODS : From a well - defined population - based cohort of CBC - patients , we have constructed a unique tissue - microarray including 600 pairs of primary tumours and CBCs . - pubmed
Patients diagnosed with two high stage tumours within a short time - interval had a particularly bad prognosis . - pubmed
Treg / Th17 balance plays a critical role in maintaining immune homeostasis of acute graft - versus - host disease ( aGVHD ) patients . - pubmed
First report of a NDM - producing Providencia rettgeri strain in the state of Sao Paulo . - pubmed
Botrytis cinerea is the causal agent of gray mold disease in various plant species and produces grayish macroconidia and/or black sclerotia at the end of the infection cycle . - pubmed
Pain is a major problem for Intensive Care Unit ( ICU ) patients . - pubmed
Despite numerous improvements it is estimated that as many as 70 % of the patients experience moderate - to - severe postoperative pain during their stay in the ICU . - pubmed
Minimizing nausea , vomiting , urinary retention , and sedation may indeed facilitate patient recovery and it is likely to shorten the ICU and hospital stay . - pubmed
The results showed that mutant strain ZJB12073 exhibited 1.9 - fold improvement in echinocandin B production to 1656.3 + - 40.3 mg / L when compared with the parent strain . - pubmed
RESEARCH DESIGN AND METHODS : Renal tubular epithelial cells ( RTECs ) from rat kidneys experiencing HS and a cell line ( HK-2 ) under hypoxia / reoxygenation ( H / R ) treatment were used . - pubmed
RESULT : Severe MD was found in rat kidneys , especially in RTECs , as evidenced by swollen mitochondria and poorly defined cristae , decreased mitochondrial membrane potential ( DeltaPsim ) , and reduced ATP content . - pubmed
Reverse takotsubo cardiomyopathy ( TCM ) is a less common variant of classic TCM that presents within a different patient profile and with its own hemodynamic considerations . - pubmed
A 46 - year - old woman was admitted to our hospital for laryngoscopy and possible balloon dilatation for tracheal stenosis under general anesthesia . - pubmed
One year prior to this admission , the patient was admitted after a motor vehicle accident with subdural hematoma , subarachnoid hemorrhage , and fracture of the eighth thoracic vertebra . - pubmed
At this admission , the patient developed acute left ventricle failure on induction of anesthesia secondary to reverse TCM . - pubmed
We report a case of reverse TCM , where posttraumatic emotional stress of a neuropsychiatric disorder combined with physical stress from anesthesia and laryngoscopy triggered TCM in a patient with previous uneventful anesthesia 1 year earlier . - pubmed
METHODS : We performed a post hoc analysis of data from the Prevention Regimen for Effectively Avoiding Second Strokes ( PRoFESS ) trial , a randomized clinical trial including 20,332 patients with recent noncardioembolic ischemic stroke . - pubmed
CONCLUSIONS : Among patients with recent noncardioembolic ischemic stroke , the risk of ICH is high . - pubmed
We report real - time cell sensing of two human cell lines to examine the cytotoxicity of fourteen arsenic species : arsenite ( AsIII ) , monomethylarsonous acid ( MMAIII ) originating from the oxide and iodide forms , dimethylarsinous acid ( DMAIII ) , dimethylarsinic glutathione ( DMAGIII ) , phenylarsine oxide ( PAOIII ) , arsenate ( AsV ) , monomethylarsonic acid ( MMAV ) , dimethylarsinic acid ( DMAV ) , monomethyltrithioarsonate ( MMTTAV ) , dimethylmonothioarsinate ( DMMTAV ) , dimethyldithioarsinate ( DMDTAV ) , 3 - nitro-4 - hydroxyphenylarsonic acid ( Roxarsone , Rox ) , and 4 - aminobenzenearsenic acid ( p - arsanilic acid , p - ASA ) . - pubmed
METHODS : A retrospective study included all patients with stage III or IV HNSCC undergoing curative VMAT . - pubmed
RESULTS : From 2010 to 2013 , 130 patients were treated for locally advanced oropharynx ( n=55 ; 42 % ) , hypopharynx ( n=38 ; 29 % ) , larynx ( n=22 ; 17 % ) or oral cavity ( n=15 ; 12 % ) SCC . - pubmed
METHODS : Seven days of activity monitor data were collected for 26 participants with MS ( age=44.5 + -11.9years ; time since diagnosis=6.5 + -6.2years ; Patient Determined Disease Steps=<=3 ) . - pubmed
This commentary points to the need for better understanding of the relationship between Hg release and AD in India , and other countries , and how to protect human health and the environment from the adverse effects of Hg . - pubmed
, angle of strabismus , ocular motility , and acuity ) for 23 consecutive patients who underwent orbital translocation between 2000 and 2015 and noted the requirement for corrective surgery . - pubmed
Nontransient change ( favorable or unfavorable ) in angle of strabismus was noted in 14 patients . - pubmed
Corrective surgery for strabismus was performed for four patients . - pubmed
The variant methionine replaces valine at 66th position is strongly related to BPD , and an individual with a homozygous condition of this allele is at a greater risk of developing MDD . - pubmed
The length of SP was measured over 30 mm in 151 patients ( 15.1 % ) . - pubmed
Here , we aimed to investigate the grey matter and white matter changes in schizophrenia patients and exhibit the relation of these imaging findings with clinical variables . - pubmed
METHODS : A total of 20 schizophrenia patients and 16 matched healthy controls underwent magnetic resonance imaging to investigate the grey matter and white matter alterations that occur in schizophrenia patients using voxel - based morphometry ( VBM ) and whole brain voxel - wise analysis of diffusion tensor imaging ( DTI ) parameters with SPM8 , respectively . - pubmed
RESULTS : Bilateral insula showed decreased grey matter volume in schizophrenia patients compared with healthy controls ( P & lt ; 0.01 ) . - pubmed
Psychiatric scores , duration of illness , and age were not correlated with the decreased grey matter volume of insula in schizophrenia patients . - pubmed
METHODS AND RESULTS : Between 2013 and 2016 , a total of 18 patients with PVT was treated with a 40 mg bolus dose of tenecteplase . - pubmed
Thrombolysis was followed by enoxaparin and oral anticoagulation in patients , all of whom had complete lysis of thrombus and clinical improvement . - pubmed
Our previous report indicated that vascular injury enhances vascular remodeling in fetal growth restriction ( FGR ) mice . - pubmed
PATIENTS AND METHOD : A descriptive cross - sectional study of 428 patients over the age of 65 admitted for trochanteric or cervical fractures in 2015 , in which gender , age , previous diagnosis , external causes associated with fracture and place of the event were recorded . - pubmed
RESULTS : There were 220 patients with a cervical fracture ( 51.4 % ) and 208 patients with a trochanteric fracture ( 48.6 % ) . - pubmed
Effects of Antiepileptic Drugs on Spontaneous Recurrent Seizures in a Novel Model of Extended Hippocampal Kindling in Mice . - pubmed
Subsequently , animals underwent continuous video / EEG monitoring for seizure detection . - pubmed
Spontaneous recurrent seizures were consistently observed in extended kindled mice but no seizures were detected in the control animals . - pubmed
No gross brain lesions were observed in a set of extended hippocampal kindled mice submitted to histological evaluation . - pubmed
Circulating Endothelial Progenitor Cells Present an Inflammatory Phenotype and Function in Patients With Alcoholic Liver Cirrhosis . - pubmed
A comprehensive characterization of circulating EPCs using more than 30 phenotype markers was performed by mass cytometer time of flight ( CyTOF ) in an independent cohort of age and gender matched ALC patients ( n = 4 ) and controls ( n = 5 ) . - pubmed
CD45int and CD45hi EPCs significantly increased in ALC patients compared to controls ( p - val = 0.006 ) . - pubmed
Conclusions : We report the first extensive characterization of circulating human EPCs with distinct EPC subtypes . - pubmed
The present study identified that microRNA ( miR-28 - 5p ) was involved in the migration and invasion of gastric cancer cells , and was able to affect the prognosis of patients with gastric cancer . - pubmed
As more and more therapeutic options are now available , we will delineate a potential therapeutic algorithm for the optimization of daily life treatment choice of NSCLC patients . - pubmed
The present study was chosen Hibiscus rosa - sinensis flowers to analyze its antimicrobial capabilities against venereal diseases causing pathogens . - pubmed
After that , the different concentrations of 1,2 benzene dicarboxylic acid were tested on human diseases causing microbial strains . - pubmed
Selective serotonin reuptake inhibitor use and mortality , postoperative complications , and quality of care in hip fracture patients : a Danish nationwide cohort study . - pubmed
Conclusion : In patients undergoing hip fracture surgery , 30 - day mortality and overall readmission risk were elevated in both current and former SSRI users compared with non - users . - pubmed
Gastric Electrical Stimulation Improves Symptoms of Diabetic Gastroparesis in Patients on Peritoneal Dialysis-2 Case Reports . - pubmed
The exact prevalence of patients with severe DGP and ESRD is not known ; however , finding a therapeutic approach to these patients , particularly those whose gastroparesis symptoms preclude them from undergoing kidney transplant procedure , represents a huge challenge . - pubmed
Our experience suggests that GES implantation can be an effective treatment modality for type 1 diabetic patients on peritoneal dialysis ( PD ) who are simultaneous pancreas - kidney transplantation candidates , by improving the severity and frequency of gastroparesis symptoms and eventually ensuring their optimal nutritional and fluid intake . - pubmed
The herbal medicine combination of notoginseng - safflower has been commonly used clinically for the prevention and treatment of cardiovascular diseases . - pubmed
METHODS : Patients with migraine aura were interviewed in order to obtain characteristics of migraine aura . - pubmed
MATERIAL AND METHODS : From September 2010 to October 2017 , radical prostatectomy was done for 123 sequential patients with localized prostate cancer in two referral centers of Shahid Beheshti Medical University , Tehran , Iran , and 42 cases with Gleason Scores 3 + 3 which who were candidates for active surveillance were included in the study . - pubmed
RESULTS : Thirty of 42 ( 71.4 % ) patients had significant tumor volumes ( & gt;=0/5 cm3 ) . - pubmed
When tumor volume was less than 0.5 cm3 , none of the patients had extra prostatic tumor extension . - pubmed
In patients with tumor volume greater than 0.5 cm3 , two cases ( 6.6 % ) had extra prostatic extension , 4 cases ( 13.3 % ) had positive margins , four cases ( 13.3 % ) reactive lymph nodes and 16 cases ( 53.3 % ) perineural invasion . - pubmed
CONCLUSION : We suggest that some patients with Gleason Score 3 + 3 have tumor volume & gt;0.5 cm3 who are considered having significant cancer pathology and active surveillance may not be appropriate approach to manage all cases with Gleason Score 3 + 3 . - pubmed
METHODS : We performed a retrospective review of TBI patients who underwent cruciate DC . - pubmed
Long - term rhythm monitoring with an implantable loop recorder in patients after the first clinical atrial fibrillation episode . - pubmed
In this work , we found that lncRNA CASC11 was significantly up - regulated in the glioma specimens and cells , and the ectopic overexpression indicated the poor prognosis of glioma patients . - pubmed
Pulmonary embolism during the third cycle of alemtuzumab in a patient with relapsing multiple sclerosis . - pubmed
This paper reports a case of young patient who developed pulmonary embolism during the third cycle of alemtuzumab . - pubmed
Nevertheless , postoperative pain remains a major challenge in patient care . - pubmed
The mid - term survival rate for the Oxford UKA in patients with morbid obesity is similar to that of other nondesigner patient series with BMI & gt;= 30 , which provides further evidence for the safety of the implant in this patient population with significant improvements on PROMs at short and mid - term follow - up . - pubmed
Objective : Aloperine ( ALO ) , an alkaloid isolated from the leaves of Sophora alopecuroides , has been suggested to exhibit anti - inflammatory and anti - tumor properties and is traditionally used to treat various human diseases , including cancer . - pubmed
This study investigated the clinical symptom profile and its associations with the results of quantitative sensory testing ( QST ) and the quantitative sudomotor axon reflex test ( QSART ) as well as the quality of life ( QOL ) in patients with clinically suspected SFN . - pubmed
METHODS : This study involved 63 patients with clinically suspected length - dependent SFN . - pubmed
, mucosal ulceration or granulation tissue in the larynx ) was present in 57 patients ( 57 % ) . - pubmed
Patients with laryngeal injury had significantly worse patient - reported breathing ( Clinical Chronic Obstructive Pulmonary Disease Questionnaire : median , 1.05 ; interquartile range , 0.48 - 2.10 ) and vocal symptoms ( Voice Handicap Index-10 : median , 2 ; interquartile range , 0 - 6 ) compared with patients without injury ( Clinical Chronic Obstructive Pulmonary Disease Questionnaire : median , 0.20 ; interquartile range , 0 - 0.80 ; p & lt ; 0.001 ; and Voice Handicap Index-10 : median , 0 ; interquartile range , 0 - 1 ; p = 0.005 ) . - pubmed
CONCLUSIONS : Acute laryngeal injury occurs in more than half of patients who receive mechanical ventilation and is associated with significantly worse breathing and voicing 10 weeks after extubation . - pubmed
Human colon carcinoma cells ( HCT 116 ) were chosen to elucidate whether DEHP triggers oxidative stress and apoptosis . - pubmed
Risk of pregnancy - related venous thromboembolism and obstetrical complications in women with inherited type I antithrombin deficiency : a retrospective , single - centre , cohort study . - pubmed
METHODS : We made a retrospective analysis of four pediatric patients diagnosed with DAH and pulmonary microangiopathy due to cblC deficiency between January 2017 and December 2018 in Beijing Children 's Hospital . - pubmed
RESULTS : This study describes four patients with their ages ranging from 4 years 2 months to 7 years 6 months with cblC deficiency who developed late - onset diffuse lung disease ( DLD ) . - pubmed
Of these , the first three patients presented predominantly with DAH , and the last patient with pulmonary microangiopathy confirmed by thoracoscopic lung biopsy . - pubmed
All patients were accompanied by pulmonary arterial hypertension ( PAH ) , two accompanied by respiratory failure , and two accompanied by moderate megaloblastic anemia . - pubmed
All patients were suspected of having idiopathic pulmonary hemosiderosis or interstitial lung disease at other hospitals . - pubmed
The samples consisted of 60 tissue specimens from patients with squamous cell carcinoma , epithelial dysplasia and controls ( n=20 / group ) . - pubmed
It is established that the products of protein metabolism , pigment , Weibel - Palade body and various sizes of blood clots accumulate in the cavity subaroundal cone of heart in old rats . - pubmed
Thyroid gland changes in patients with acromegaly . - pubmed
The aim of the present study was to find the prevalence of thyroid dysfunction and goiter in patients with acromegaly and determine its relationship to disease activity , disease duration , and the presence of secondary hypothyroidism . - pubmed
SUBJECTS AND METHODS : In a cross - sectional study of the period 2008 - 2012 were included 146 patients with acromegaly ( 56 men , 90 women ) of mean age 50.3 + - 12.4 years . - pubmed
Acromegaly disease activity and thyroid function were evaluated in all patients . - pubmed
Goiter was diagnosed in 87 % of patients , including diffuse goiter ( 17.1 % ) and nodular ( 69.9 % ) , with no significant difference between patients with active and controlled disease or the presence of secondary hypothyroidism . - pubmed
CONCLUSIONS : Thyroid volume in patients with acromegaly depends on disease activity and the presence of secondary hypothyroidism as a complication . - pubmed
The increased prevalence of nodular goiter determines the need of regular ultrasound thyroid evaluation in the follow - up of patients with acromegaly . - pubmed
L can enter the human organism during the treatment of helminthiasis as well as during the using the contaminated cocaine . - pubmed
Cancer - related death was particularly increased in patients with low RTE levels ( 4.23 ; 95%CI , 1.43 - 12.13 ; p = 0.007 ) . - pubmed
Studies reported that tobacco addiction was related to visual impairments , but one unresolved issue is whether the impairments are related to the many compounds existing in the cigarettes or to the effects of nicotine . - pubmed
Inter - reader agreement of high - resolution computed tomography findings in patients with COVID-19 pneumonia : A multi - reader study . - pubmed
METHOD : Seventy - seven consecutive patients ( mean age , 64 + - 15 years ) with mild COVID-19 pneumonia that underwent HRCT were retrospectively included . - pubmed
This study evaluated the effects of probiotic and selenium co - supplementation on clinical and metabolic symptoms in patients with chronic schizophrenia . - pubmed
A randomized , double - blind , placebo - controlled trial was conducted among 60 people with chronic schizophrenia to receive either 8 x 109 CFU / day probiotic plus 200 mug / day selenium ( n = 30 ) or placebo ( n = 30 ) for 12 weeks . - pubmed
Probiotic and selenium co - supplementation for 12 weeks to patients with chronic schizophrenia had beneficial effects on the general PANSS score and some metabolic profiles . - pubmed
Human PRV Infection in China : An Alarm to Accelerate Eradication of PRV in Domestic Pigs . - pubmed
A value of r = 0,86 and 0,85 was found for both fixed and variable area radionuclide methods when these ejection fraction values were correlated with cardio - angiographic ejection fraction values in normal subjects and in patients with myocardial infarction . - pubmed
[ Studies on correlation between alterations in serum sialic acid levels and remission , metastasis , and recurrence of diseases in patients with cancer ( author 's transl ) ] . - pubmed
Positive results obtained in the three methods were particularly found in patients with diseases generally presumed to represent immune complexes diseases including acute glomerulonephritis , systemic lupus erythematosus , polyarteritis nodosa , subacute bacterial endocarditis , and acute or chronic hepatitis . - pubmed
We observed idiopathic light - chain proteinuria in a patient with multiple abnormalities of proximal - tubule transport mechanisms ( Fanconi syndrome ) , nephrogenic diabetes insipidus , and distal renal tubular acidosis . - pubmed
A 29 year old woman is described with severe hyperemesis gravidarum , atypical migraine , numerous admissions to hospital for psychiatric illness , non - epileptic seizures , and valproate - induced coma . - pubmed
Thirty - four patients who had resection of cancer of the pancreatic head were examined clinicopathologically to elucidate neural invasion of cancer of the pancreatic head to the extrapancreatic nerve plexus . - pubmed
Invasion of cancer to the retropancreatic tissue ( rp+ ) was observed in 29 ( 85 % ) of the 34 patients , and neural invasion to the extrapancreatic nerve plexus was observed in 21 ( 72 % ) of the 29 patients with rp+ . - pubmed
Complex study of cellular and humoral defense reactions in patients with acute cholecystitis revealed a decrease in their level , decelerated change of the neutrophil phase to the mononuclear phase , and increased metabolic phagocyte activity in the focus of affection . - pubmed
[ Epilepsy detected in diabetes in patients over 50 years ] . - pubmed
Epilepsy over the age of 50 years represents 14 % of the persons hospitalized in this age group , and 32 % of all epileptics hospitalized at Dakar U. H. C. The etiologies of these epilepsies reveal 8.30 % metabolic encephalopathics , and 3.35 % diabetics . - pubmed
The effects of glucocorticoids on the availability of L - tryptophan and tyrosine in the plasma of depressed patients . - pubmed
In order to investigate the effect of glucocorticoid excess on the availability of L - TRP and tyrosine to the brain , we measured urinary cortisol ( UC ) excretion in 24 - h urine , and the availability of both amino acids before and after treatment with 1 mg dexamethasone in 26 depressed patients . - pubmed
Major depressed patients with melancholia exhibited a significantly lower availability of L - TRP than minor depressives ( P = 0.007 ) . - pubmed
[ Role of drug assays in the treatment of epileptic patients ] . - pubmed
Indications for pelvic lymph node dissection in patients with clinically confined carcinoma of the prostate . - pubmed
The combination of haloperidol , 5 mg , and lorazepam , 4 mg , was both effective and safe for managing agitated behavior in an open trial with acutely psychotic patients . - pubmed
Ongoing electrical activity of superior cervical ganglion cells in mammals of different size . - pubmed
The ongoing synaptic activity of superior cervical ganglion cells in adult mammals was examined in situ by intracellular recording in anesthetized mice , hamsters , rats , guinea pigs , and rabbits . - pubmed
Viraemia with human parvovirus . - pubmed
Cyclosporine therapy in chronic slowly progressive polymyositis -- preliminary report of clinical results in three patients . - pubmed
[ Studies on anti - arrhythmia effects of panaxatriol saponins isolated from Panax notoginseng ] . - pubmed
Using a logistic discriminant function we retrospectively evaluated the diagnostic value of laboratory features and abdominal sonography in 70 patients with jaundice . - pubmed
18 patients had an extrahepatic obstruction of the common bile duct ( EHO ) , 22 patients had metastatic liver disease ( MLD ) and 30 patients had an infectious or toxic hepatocellular disease ( HCD ) . - pubmed
An undoubtedly dilated common bile duct was seen in 56 % of the patients with EHO and in none of the other patients . - pubmed
Metastatic lesions were seen exclusively in 81 % of the patients with MLD . - pubmed
No distinct sonographic sign could be found for the patients with HCD . - pubmed
Biosynthesis of leukotoxin , 9,10 - epoxy-12 octadecenoate , by leukocytes in lung lavages of rat after exposure to hyperoxia . - pubmed
Age was significantly correlated ( P less than 0.0002 ) with lateral ventricular size , but the institutionalized schizophrenic patients had significantly larger ( P less than 0.025 ) lateral ventricles than the neurotics when age was taken into account . - pubmed
Within the group of institutionalized schizophrenic patients few correlates of ventricular enlargement were identified ; thus in this population increased ventricular size was not clearly associated with the features of the defect state ( negative symptoms and intellectual impairment ) . - pubmed
[ Study of a transplantable epidermoid epithelioma of the skin of the C3H mouse ] . - pubmed
Hypnosis in the treatment of a child 's allergy to dogs . - pubmed
Rabies today -- man and animals . - pubmed
Studies on homotransplantable lymphomas in hamsters . - pubmed
[ Biological effects of the combined action of laser radiation and methylene blue on a strain of Salmonella typhimurium ( TA 1538 ) ( I ) ] . - pubmed
A new set of trials they are making on Salmonella typhimurium TA 100 strain with plasmid pK M 101 that give to strain greatest susceptibility for mutagenetic agents . - pubmed
Lymphocyte cytotoxicity in the peritoneal cavity and blood of patients with ovarian cancer . - pubmed
After an intensive course of combination chemotherapy , 16 patients with minimal residual ovarian cancer that was documented at second - look laparotomy , had an indwelling Tenckhoff catheter placed and underwent multiple peritoneal saline lavages . - pubmed
Peritoneal natural killer lymphocyte cytotoxicity and antibody - dependent cell - mediated cytotoxicity were very low in all but two patients . - pubmed
These results suggest that lymphocytes collected from the peritoneal cavity of patients with minimal residual ovarian cancer are deficient in natural and antibody - dependent cytotoxic effector function . - pubmed
A phase II study of the combination , 1,3 - bis ( 2 - chloroethyl )- 1 - nitrosourea ( BCNU ) and N -( phosphonacetyl )- L - aspartate ( PALA ) , in patients with advanced large bowel cancer . - pubmed
Thirty patients with advanced metastatic colorectal carcinoma were treated with the combination BCNU ( 200 mg / m2 ) every 6 weeks , and PALA ( 5.0 g / m2 ) every 3 weeks . - pubmed
Control of susceptibility of F344 rats to adjuvant arthritis : an alternative interpretation . - pubmed
Diastolic murmur ( DM ) in patients with non - obstructive hypertrophic cardiomyopathy ( non - obst HCM ) was studied regarding incidence , phonocardiographic disposition , mechanism , and also clinical characteristics of patients with DM . - pubmed
The results were as follows : 1 ) DM was recorded in 17 of 115 patients with non - obst HCM ( 15 % ) , and was classified into three types of a mid - diastolic murmur , presystolic murmur , presystolic murmur and these combination . - pubmed
Therefore , auscultatory or phonocardiographic assessment of DM was clinically useful in the evaluation of patients with non - obst HCM . - pubmed
In the past five years , the use of chemotherapy has also assumed a major role in treating micrometastases in breast cancer in selected premenopausal and postmenopausal patients . - pubmed
Similar nuclear changes have until now only been reported in man in relation to tumors or other pathological conditions . - pubmed
We studied two patients who manifested many of the varied clinical signs of Vogt - Koyanagi - Harada syndrome , but who also showed focal neurologic involvement , including acute transverse myelitis and ciliary ganglionitis . - pubmed
Preliminary inhalation of oxygen in conscious rabbits prevents increased respiratory muscle activity caused by airway occlusion . - pubmed
Chronically ill institutionalized children : psychosocial effects of prolonged hospitalization of the terminally sick child . - pubmed
Electropalatographic and perceptual analysis of the speech of Cantonese children with cleft palate . - pubmed
This study used electropalatographic and perceptual analysis to investigate the speech of two Cantonese children with repaired cleft palate . - pubmed
beta blockers have been shown to decrease subsequent cardiovascular events in patients with acute myocardial infarction ; however , adverse effects are often associated with their use . - pubmed
In patients with coronary artery disease and symptoms resulting from either fixed obstruction or vasospasm , these agents decrease the frequency of angina episodes . - pubmed
Calcium antagonists appear to be well tolerated in patients with concomitant conditions such as diabetes and are effective in commonly coexistent cardiovascular disorders such as hypertension . - pubmed
MATERIALS AND METHODS : Thirty - one patients with autonomous thyroid nodules underwent a cycle of treatment with percutaneous injection of ethanol in multiple sessions ( three to seven ) on alternate days depending on the diffusion of the ethanol in the nodule . - pubmed
Symptoms resolved in 73 % of the hyperthyroid subjects after the first cycle of treatment and in 93 % of these subjects after the second . - pubmed
Diarrheal illness without concomitant respiratory symptoms was monitored among 221 children aged & lt ; 3 years in 37 classrooms ( 24 day - care centers ) through biweekly parental telephone interviews from October 1988 to May 1989 in Cumberland County , North Carolina . - pubmed
Helicobacter pylori is probably the most common bacterial infection worldwide and the accepted cause of chronic active gastritis . - pubmed
What is true for duodenal ulcers is also true for patients with gastric ulcer who are infected with H. - pubmed
The risk of recurrent ulcer complications with bleeding is virtually abolished following successful eradication of H. - pubmed
At this time it is reasonable to consider all patients with confirmed duodenal or gastric ulcer for eradication of H. - pubmed
An abattoir - based study of the prevalence of subclinical Johne ' s disease in adult cattle in south west England . - pubmed
The prevalance of subclinical Johne ' s disease was estimated in adult cattle slaughtered at three major abattoirs in south west England . - pubmed
OBJECTIVE : The decision to perform total hip arthroplasty ( THA ) in patients with osteoarthritis ( OA ) of the hip is based largely on patients ' reports of pain and disability and not on radiographic findings of OA . - pubmed
METHODS : Individual radiographic features ( osteophytes , joint space narrowing , sclerosis , cysts , deformity ) and global severity of hip OA were assessed in 95 consecutive elderly patients with hip OA undergoing THA who were enrolled in a Patient Outcome Research Team ( PORT ) project . - pubmed
RESULTS : Eighty - seven patients ( 91.5 % ) had either severe or moderate OA in the hip to be replaced ; 17 % of these had a previous contralateral THA . - pubmed
Eight patients with either primary or secondary osteoarthritis of the hip received uncemented total hip prostheses . - pubmed
Patients with epilepsy develop psychosis or schizophrenia at a rate exceeding that expected if the two disorders were independent . - pubmed
Neuropathological investigations into the anatomic substrate of seizures in patients with psychosis or schizophrenia are consistent with the notion that there are neurodevelopmental abnormalities involving the mesial temporal lobe . - pubmed
Finally , clinical recommendations for the evaluation and pharmacological management of patients with schizophrenia who have one or more seizures are described . - pubmed
PURPOSE : To report treatment of a patient with acute retinal necrosis during pregnancy . - pubmed
METHODS : A 24 - year - old woman in her twenty - third week of gestation was diagnosed with acute retinal necrosis . - pubmed
The pancreatic lesion masses were found in all the non - AIDS patients and in one patient with AIDS and were located in the head of the pancreas in two cases and involved the body , neck , and head of the gland in the other two . - pubmed
In patients with right ventricular failure , a decrease in afterload was attained by a cavo - bipulmonary anastomosis associated with the intraventricular repair . - pubmed
The authors conclude that high risk patients with Ebstein ' s anomaly have a lower operative mortality and improved functional tolerance when there is persistent tricuspid regurgitation after cavo - bipulmonary anastomosis . - pubmed
Epileptic seizures are a principal brain dysfunction with important public health implications , as they affect 0.8 % of humans . - pubmed
Our objective was to follow the transition into seizure by reconstructing intracranial recordings in implanted patients as trajectories in a phase space and then introduce non - linear indicators to characterize them . - pubmed
Recommendations for the treatment of lipid disorders in patients on peritoneal dialysis . - pubmed
It seeks to determine the annual transition probabilities from chronic hepatitis to cirrhosis and the HCV incidence per year in the past . - pubmed
These unknowns are found by fitting the observed deaths from HCC that are attributable to HCV . - pubmed
Optimal values for these unknowns then allow to project the number of HCC deaths attributable to HCV for each year through 2025 ( for patients infected before 1996 ) . - pubmed
It predicts that HCC mortality related to HCV will continue to increase through 2020 in the absence of treatment , with a 150 % increase in the yearly incidence among men and 200 % among women . - pubmed
The metabolism of glucose and cellobiose , products of cellulose hydrolysis , was investigated in four cellulolytic strains of the genus Fibrobacter : Fibrobacter succinogenes S85 , 095 , HM2 and Fibrobacter intestinalis NR9 . - pubmed
Can coronary blood flow velocity pattern after primary percutaneous transluminal coronary angioplasty [ correction of angiography ] predict recovery of regional left ventricular function in patients with acute myocardial infarction ? - pubmed
This study sought to investigate parameters derived from the coronary blood flow velocity spectrum immediately after primary PTCA in patients with acute myocardial infarction and to elucidate the clinical value of coronary blood flow measurement in predicting myocardial viability . - pubmed
METHODS AND RESULTS : Using a Doppler guidewire , we measured coronary blood flow velocity after successful completion of primary PTCA in 23 consecutive patients with acute anterior myocardial infarction . - pubmed
When 9 patients with a daily intake of SPC and a citrate excretion below 2.5 mmol / day were compared with 16 hypocitraturic patients only given drinking advice , the cumulated percentages of patients without recurrent stone formation in the 2 groups after 3 years were 44 % and 48 % , respectively . - pubmed
The rate of stone formation was apparently slightly reduced , but the fraction of patients free of recurrence was no different from that in patients without medical treatment . - pubmed
RESULTS : A total of 116 patients with confirmed GBC were admitted during these five years . - pubmed
We analyzed the results of a three or more drug combination as treatment for moderate or severe cGVHD developing after transplantation for thalassemia , in 45 patients with median age of 11 ( range 2 - 26 ) years . - pubmed
This retrospective study showed that a three or more drug combination is safe and effective for treatment of moderate or severe cGVHD at least in younger patients . - pubmed
78.26 % patients with peptic ulcer associated with H. - pubmed
pylori ( Toxin+ ) , while 42.86 % patients with gastritis was infected with H. - pubmed
There was a closed relationship between infection with H. - pubmed
Bilateral human fetal striatal transplantation in Huntington ' s disease . - pubmed
BACKGROUND : Transplanted striatal cells have been demonstrated to survive , grow , establish afferent and efferent connections , and improve behavioral signs in animal models of Huntington ' s disease ( HD ) . - pubmed
OBJECTIVE : To evaluate feasibility and safety and to provide preliminary information regarding the efficacy of bilateral human fetal striatal transplantation in HD . - pubmed
METHODS : Seven symptomatic patients with genetically confirmed HD underwent bilateral stereotactic transplantation of two to eight fetal striata per side in two staged procedures . - pubmed
RESULTS : Three subjects developed subdural hemorrhages ( SDHs ) and two required surgical drainage . - pubmed
One subject died 18 months after surgery from probable cardiac arrhythmia secondary to severe atherosclerotic cardiac disease . - pubmed
Patients with moderately advanced HD are at risk for SDH after transplantation surgery . - pubmed
Human infection with Nocardia species presents as a wide range of clinical syndromes . - pubmed
We report a case of primary Nocardia asteroides osteomyelitis as the initial clinical presentation of AIDS . - pubmed
The most common species isolated from cases of pityriasis versicolor was M. - pubmed
In both adult and suckling infant cases of seborrhoeic dermatitis , M. - pubmed
In addition , scales were collected from lesions of pityriasis versicolor for use as the template , and the involved Malassezia species were identified by the PCR method using the DNA sequences of nuclear ribosomal internal transcribed spacer l. The most commonly detected species was M. - pubmed
The expression of human blood type antigens in Neijiang pigs was different from other pig strains reported , it was suggested that it was possible to find a pig strain that contained less xenoantigen . - pubmed
These acute effects demonstrate the possibility of functional and metabolic amelioration by TMLR after ischemia induced by microembolization in an isolated hemoperfused pig heart . - pubmed
The brain matrix and multifocal brain damage following a single injection of ketamine in young adult rats : conspicuous changes in old age . - pubmed
The rats which had received the ketamine after the seizures were significantly heavier than either the normal rats or the other group of seized rats . - pubmed
Compared to the acepromazine - treated rats , the ketamine - treated rats did not exhibit spontaneous seizures and exhibited cerebral widths comparable to normal rats . - pubmed
EXPERIMENTAL DESIGN : We performed gene expression analysis on mesothelioma tissue specimens from 16 patients and compared these to 4 control pleural tissue samples using cDNA microarray filters with 4132 clones . - pubmed
Excess weight gain is a major cause of increased blood pressure in most patients with essential hypertension , and also greatly increases the risk for renal disease . - pubmed
Special considerations for the obese patient , in addition to adequately controlling the blood pressure , include correction of the metabolic abnormalities and protection of the kidneys from further injury . - pubmed
Electroencephalographic findings in children , previously treated for asphyxia neonatorum . - pubmed
There were 119 patients ( 44 female and 75 male ): 73 patients had simple d - TGA , 36 had d - TGA with ventricular septal defect , and 10 had a Taussig - Bing heart . - pubmed
At latest follow - up , there was no or trivial AR in 88 patients , mild AR in 29 patients , and moderate to severe AR in 3 patients . - pubmed
Only 3 patients required surgical intervention for AR . - pubmed
[ Biological support of Echinococcus granulosus and epidemiology of hydatidosis ] . - pubmed
[ Streptomycin therapy of human tuberculosis and associated diseases ] . - pubmed
Patient with diabetes mellitus is prone to develop the vascular lesion of blood vessels of all kinds . - pubmed
Also with this study blood brain barrier change in the diabetes mellitus patients was observed . - pubmed
In patients with diabetes mellitus the level of glucose and total proteins increased in the cerebrospinal fluid . - pubmed
Blood brain barrier permeability changes in the patients with ICV as well as in the patients without ICV correlate with the values of diabetes mellitus in blood . - pubmed
While the wild - type strain effectively kills the nematode Caenorhabditis elegans , the pathogenicity of mutants with defective quorum sensing is attenuated . - pubmed
cenocepacia but also by many other strains of the Burkholderia cepacia complex . - pubmed
How is pulmonary arterial blood flow affected by pulmonary venous obstruction in children ? - pubmed
MATERIALS AND METHODS : Twelve children ( age range 3 - 180 months ) who had undergone MRI for pulmonary vein stenosis were identified . - pubmed
Nine of the patients had unilateral stenosis ; three had bilateral involvement . - pubmed
RESULTS : Unilateral vein stenosis was associated with diastolic reversal in the ipsilateral branch pulmonary artery ( mean flow reversal 12.3 % , range 2.4 - 42 % ) and continuous diastolic forward flow in the contralateral pulmonary artery in seven of nine patients . - pubmed
All patients sustaining acute biliary pancreatitis were enrolled . - pubmed
Patients with clinical jaundice and severe pancreatitis were excluded . - pubmed
All patients underwent intra - operative cholangiography ( IOC ) or pre - operative endoscopic retrograde cholangiography ( ERCP ) , which was indicated based on the odds of choledocholithiasis . - pubmed
CONCLUSION : The best predictor of choledocholithiasis in patients sustaining mild acute pancreatitis was the biliary tract dilatation in pre - operative US . - pubmed
Preliminary examination of VaD subtypes revealed patients with subcortical infarct or SH - only exhibited greater decline than VaD patients with cortical lesions . - pubmed
Yet , RA preferentially affects elderly individuals , in whom adaptive immunity to exogenous antigens begins to fail . - pubmed
Complete response was observed in 3 ( 7.9 % ) patients , partial response in 20 ( 52.6 % ) ( overall response rate 60.5 % ) , stable disease in 11 ( 28.9 % ) and disease progression in 4 ( 10.5 % ) . - pubmed
Rates of decline in soil were similar in the laboratory at 20 degrees C for two strains of L. - pubmed
METHODS : Dextran sodium sulfate - induced colitis and Salmonella typhimurium - induced enterocolitis were used as animal models to study colitis . - pubmed
The case reported herein describes a 12 - year - old boy affected by cranio - facial dysmorphism and monolateral conductive hearing loss in the right ear : followed from radiological diagnosis -- carried out to study a malformation of the ear pinna -- to surgical treatment . - pubmed
We describe the first case of Pisa syndrome during aripiprazole treatment in an elderly ( 77 - year - old ) woman , admitted to hospital for behavioural and psychological symptoms of dementia . - pubmed
In vivo , PXD101 displayed single - agent antitumor activity on human A2780 ovarian cancer s.c . - pubmed
METHODS : The patients were healthy premenopausal women with HSDD , aged 22 - 50 years . - pubmed
CONCLUSION : The result of this study suggests that COCs in premenopausal women with HSDD are associated with lower androgen levels than those not on COCs . - pubmed
Our results demonstrate that in contrast to laxaphycin A , laxaphycin B inhibits the proliferation of sensitive and resistant human cancer cell lines and that this activity is strongly increased in the presence of laxaphycin A. - pubmed
Carbon dioxide ( CO ( 2 ) ) is required for growth of Actinobacillus actinomycetemcomitans ( Aa ) , the reputed cause of LAgP. - pubmed
Bicarbonate , a source of CO ( 2 ) , buffers acid production by Streptococcus mutans ( Sm ) , a key organism associated with caries . - pubmed
The purpose of this study was to determine whether the saliva of LAgP patients and subjects with Aa had higher levels of bicarbonate , or an elevated pH , and/or reduced survival of Sm . - pubmed
Patient- and death - censored graft survival at 12 months were 86 % and 88 % , respectively . - pubmed
Bacterial ( 0.66 + /- 1.0 vs 1.48 + /- 1.26 infections per patient per year , P = .009 ) and viral infections ( 0.9 + /- 0.71 vs 1.41 + /- 0.71 ; P = .006 ) were more frequent in the higher dose group . - pubmed
aeruginosa , the peptide highly protected mice against death by sepsis . - pubmed
Hearing impairment is the most common sensorineural disorder in humans . - pubmed
Incretin levels and effect are markedly enhanced 1 month after Roux - en - Y gastric bypass surgery in obese patients with type 2 diabetes . - pubmed
Tuning major gene variants conditioning human behavior : the anachronism of ADHD . - pubmed
The median survival of brain metastasis patients with breast cancer of 19 months appears favorable compared with the general brain metastasis population . - pubmed
[ Validation of MRI and 18F - FDG - PET coregistration in patients with primary brain tumors ] . - pubmed
OBJECTIVE : To evaluate the role of PET and MRI fused image study inpatients with primary brain tumors previously treated , to determine the presence of radionecrosis vs residual tumor viability . - pubmed
RESULTS : Fifty - seven patients were studied , 37 had high grade gliomas ; 9 had oligoastrocytomas ; 5 had Embrionary tumors ; I had a meningyoma and I had an oliodendroglial tumor . - pubmed
Gene expression of cold shock and other stress - related genes in Vibrio vulnificus grown in pure culture under shellstock temperature control conditions . - pubmed
Shellstock refrigeration after harvesting is recommended to prevent further increases in Vibrio vulnificus numbers in oysters , but it could potentially induce a cold shock response in this bacterium . - pubmed
139 patients with achalasia of cardiac orifice among which two third were women and one third -- men aged 20 - 65 years have been observed . - pubmed
Renal sparing surgery for children with bilateral Wilms tumor . - pubmed
BACKGROUND / AIMS : In patients with hepatocellular carcinoma ( HCC ) exceeding the Milan criteria , the recurrence rate after liver transplantation is over 50 % . - pubmed
We investigated pretransplant factor(s ) that could predict recurrence after living donor liver transplantation ( LDLT ) in patients with HCC exceeding the Milan criteria . - pubmed
METHODS : Pre - operative imaging showed that , of the 111 HCC patients who underwent LDLT between June 1995 and January 2006 , 37 exceeded the Milan criteria . - pubmed
The 2 - year HCC recurrence rates in patients with 0 , 1 , 2 and 3 factors were 0 % ( 0/4 ) , 9 % ( 1/16 ) , 80 % ( 8/10 ) and 100 % ( 7/7 ) respectively ( P<0.001 ) . - pubmed
CONCLUSIONS : In patients with HCC exceeding the Milan criteria , the three pretransplant factors that may be useful for identifying those with high HCC recurrence potential after LDLT are tumour size & gt;6 cm , progressive disease after pretransplant treatment and tumour exposed to the liver surface . - pubmed
BACKGROUND : Efavirenz is used for the antiretroviral treatment of HIV / tuberculosis - coinfected patients in developing countries . - pubmed
Phase 3 trials in patients with advanced , metastatic , hormone refractory prostate cancer are under way . - pubmed
Ciguatera fish poisoning : treatment , prevention and management . - pubmed
INTRODUCTION : Case studies indicate that cardiac sarcoid may mimic the clinical presentation of arrhythmogenic right ventricular dysplasia / cardiomyopathy ( ARVD / C ) ; however , the incidence and clinical predictors to diagnose cardiac sarcoid in patients who meet International Task Force criteria for ARVD / C are unknown . - pubmed
METHODS AND RESULTS : Patients referred for evaluation of left bundle branch block ( LBBB)-type ventricular arrhythmia and suspected ARVD / C were prospectively evaluated by a standardized protocol including right ventricle ( RV ) cineangiography - guided myocardial biopsy . - pubmed
Sixteen patients had definite ARVD / C and four had probable ARVD / C. Three patients were found to have noncaseating granulomas on biopsy consistent with sarcoid . - pubmed
Age , systemic symptoms , findings on chest X - ray or magnetic resonance imaging ( MRI ) , type of ventricular arrhythmia , RV function , ECG abnormalities , and the presence or duration of late potentials did not discriminate between sarcoid and ARVD / C. Left ventricular dysfunction ( ejection fraction & lt;50 % ) was present in 3/3 patients with cardiac sarcoid , but only 2/17 remaining patients with definite or probable ARVD / C ( P = 0.01 ) . - pubmed
CONCLUSIONS : In this prospective study of consecutive patients with suspected ARVD / C evaluated by a standard protocol including biopsy , the incidence of cardiac sarcoid was surprisingly high ( 15 % ) . - pubmed
Nontuberculous mycobacteria ( NTM ) are human opportunistic pathogens with an environmental source of infection . - pubmed
AIMS : To evaluate effects of physiotherapeutic intervention in terms of self- and manual mobilization on chest expansion , vital capacity , posture , spine mobility and experienced consequences of the disease in patients with ankylosing spondylitis . - pubmed
METHODS : Thirty - two men , aged between 23 and 60 years , with ankylosing spondylitis were randomized to active or no treatment for eight weeks . - pubmed
CONCLUSION : This study shows that eight weeks of self- and manual mobilization treatment improved chest expansion , posture and spine mobility in patients with ankylosing spondylitis . - pubmed
Postoperative myocardial damages are a key issue in patients ' outcome after hip fracture . - pubmed
Effect of alpha lipoic acid on the tardive dyskinesia and oxidative stress induced by haloperidol in rats . - pubmed
Increased levels of thiobarbituric acid reactive products are found in the cerebrospinal fluid and plasma of patients treated with neuroleptics , especially those with movement disorders . - pubmed
Infestation by Pyemotes tritici ( Acari , Pyemotidae ) causes death of stingless bee colonies ( Hymenoptera : Meliponina ) . - pubmed
Anaplasma phagocytophilum is the recently designated name replacing three species of granulocytic bacteria , Ehrlichia phagocytophila , Ehrlichia equi and the agent of human granulocytic ehrlichiosis , after the recent reorganization of the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales . - pubmed
Tick - borne fever ( TBF ) , which is caused by the prototype of A. - pubmed
Until the discovery of human granulocytic anaplasmosis ( HGA ) in the USA in 1994 , these organisms were thought to be distinct species of bacteria infecting specific domestic animals and free - living reservoirs . - pubmed
Ruminants with TBF and humans with HGA develop severe febrile reaction , bacteraemia and leukopenia due to neutropenia , lymphocytopenia and thrombocytopenia within a week of exposure to a tick bite . - pubmed
Because of the severe haematological disorders lasting for several days and other adverse effects on the host 's immune functions , infected animals and humans are more susceptible to other infections . - pubmed
A 52 - year - old man had progressively worsening right knee pain and swelling of 3 years ' duration that had been treated conservatively for 6 months . - pubmed
Axillary lymph node samples derived from breast cancer patients were measured by Raman microspectroscopy . - pubmed
The primary end - point -- mean 4 - year GFR by aMDRD -- ascribed " 0 " to patients who experienced death or graft loss after 2 years . - pubmed
METHODS : This study included 110 patients with spinal TB and 102 volunteers as controls . - pubmed
OBJECTIVES : The aim of this randomized controlled study was to cephalometrically assess possible changes in craniofacial morphology associated with long - term use of an adjustable oral - appliance compared with continuous positive airway pressure ( CPAP ) in patients with the obstructive sleep apnea / hypopnea syndrome ( OSAHS ) . - pubmed
Fifteen sheep with anthracycline - induced NICM were assigned to catheter - based , transendocardial injections of allogeneic MPC ( n = 7 ) or placebo ( n = 8) , under electromechanical mapping guidance . - pubmed
Cell transplantation was associated with 1 death late in follow - up , compared with 3 early deaths among placebo animals . - pubmed
Fourteen patients with proven neuroborreliosis served as the control group . - pubmed
All EBV cases had a pleocytosis with significantly increased mononuclear leukocytes as compared to the neuroborreliosis group ( median 99 % interquartile range ( 96 - 100 % ) versus 90 % ( 86 - 97 % ) . - pubmed
Enterotoxigenic Escherichia coli ( ETEC ) is recognized to be a common cause of acute watery diarrhea in children from developing countries . - pubmed
MATERIALS AND METHODS : We retrospectively evaluated the pre - operative studies of 60 patients with primary ( n=56 ) and secondary ( n=4 ) hyperparathyroidism . - pubmed
We performed subcellular fractionation of human endothelial cells ( EA.hy926 ) after a challenge with dengue virus serotype-2 ( DEN-2 ) at multiplicity of infection ( MOI ) of 10 for 2 h. The cells were fractionated into four fractions including cytosol , membrane / organelle , nucleus and cytoskeleton , and their purity was nicely confirmed by immunofluorescence staining of markers for individual subcellular compartments . - pubmed
METHODS : Procedural billing codes and the electronic medical records of patients undergoing revascularization for carotid artery stenosis from February 2007 through March 2010 were used for data collection . - pubmed
The carotid artery stenosis was symptomatic in 42 % of these patients . - pubmed
Clinical , electrophysiological , and MRI findings in patients with cerebellar ataxia and a bilaterally pathological head - impulse test . - pubmed
A significant number of patients with bilateral vestibulopathy suffer from cerebellar ataxia and central vestibular symptoms and vice versa . - pubmed
We examined 31 patients presenting with the combination of gait and stance ataxia , cerebellar ocular motor signs , and a bilaterally pathological head - impulse test ( HIT ) . - pubmed
Twenty - three patients had evidence of polyneuropathy ( predominantly mixed sensorimotor involving axonal loss and demyelination ) and twenty of hypoacusis ( 1 unilateral and 19 bilateral ) . - pubmed
Voxel - based morphometry comparing local gray matter brain volume between patients and controls revealed cerebellar atrophy involving both the vermis and the hemispheres . - pubmed
This multisensory syndrome is most likely caused by a neurodegenerative disorder affecting different systems , leading to severe impairment of affected patients . - pubmed
Hepatoprotective activity of the Phyllanthus species on tert - butyl hydroperoxide ( t - BH)-induced cytotoxicity in HepG2 cells . - pubmed
BACKGROUND : Phyllanthus ( Euphorbiaceae ) species have long been used in folk medicine to treat various pathological conditions including liver diseases . - pubmed
MATERIALS AND METHODS : The extracts were evaluated for hepatoprotective activity against tert - butyl hydroxide ( t - BH)-induced cytotoxicity using human hepatocarcinoma cells ( HepG2 cell line ) . - pubmed
Minimal - invasive magnetic heating of tumors does not alter intra - tumoral nanoparticle accumulation , allowing for repeated therapy sessions : an in vivo study in mice . - pubmed
First Report of Intestinal Myiasis Due To Eristalis tenax in Iran . - pubmed
Intestinal myiasis caused by E. - pubmed
We report the case of a 43 - years - old man with a painful tumefaction of the left hypothenar region . - pubmed
The patient underwent surgery to resolve the ulnar nerve compression and revascularise the artery . - pubmed
Dietary fatty acids modulate liver mitochondrial cardiolipin content and its fatty acid composition in rats with non alcoholic fatty liver disease . - pubmed
We determined the content of mitochondrial membrane phospholipids from rats with non alcoholic liver steatosis , with a particular attention for cardiolipin ( CL ) content and its fatty acid composition , and their relation with the activity of the mitochondrial respiratory chain complexes . - pubmed
The Pasteurella multocida toxin : a new paradigm for the link between bacterial infection and cancer . - pubmed
The concept that bacterial infection could cause cancer has only recently become accepted because of the strong epidemiological and molecular evidence for a major carcinogenic role played by Helicobacter pylori . - pubmed
The diagnosis of tuberculosis is seriously hampered in the absence of standard biosafety laboratory facilities for specimen concentration and Mycobacterium tuberculosis culture . - pubmed
All these factors were significantly upregulated in the POEMS syndrome patients . - pubmed
Chyloperitoneum , chylothorax and lower extremity lymphedema in woman with sporadic lymphangioleiomyomatosis successfully treated with sirolimus : a case report . - pubmed
Recent studies report effectiveness of sirolimus in LAM patients . - pubmed
We report the case of a 45 - year - old woman with sporadic LAM , successfully treated with sirolimus , in whom the first manifestation of the disease was chyloperitoneum and after three and nine years , respectively , lymphedema of the left lower extremity and right sided chylothorax occurred . - pubmed
This paper examines the case of a 37 - year - old male patient reported to have developed noncardiogenic pulmonary edema after intravenous injection of gadobutrol during MRI . - pubmed
The clinical presentation varies with the amount of triglycerides in the blood and completely resolves with lowering triglyceride levels , making this condition transient with no visual symptoms ; CASE REPORT : A 46 - year old white man presented with lipemia retinalis and , hours later , to the Emergency department with acute pancreatitis secondary to hypertriglyceridemia ; CONCLUSION : Lipemia retinalis warrants an immediate complete blood count and lipid panel to Determine triglyceride levels with referral to a primary care provider . - pubmed
The Minimal Inhibitory Concentration ( MIC ) varied from 0.5 to 1.5 mg / mL and 1.25 to 2 mg / mL for yeast and bacterial strains , respectively . - pubmed
The optical density value in rats with brain ischemia significantly increased , compared with sham one ( P<0.05 ) . - pubmed
PARTICIPANTS : Women with stress or mixed urinary incontinence with predominantly stress urinary incontinence . - pubmed
A 72 - year - old man presented with palpitation , dyspnea , and chest discomfort . - pubmed
[ A case in which XELOX plus bevacizumab chemotherapy was effective in an elderly patient with heart failure and multiple liver metastases after sigmoidectomy ] . - pubmed
A 75 - year - old woman with a chief complain of anal pain visited the emergency department . - pubmed
Six days after drainage , the patient 's condition progressed to acute respiratory failure due to heart failure , and ventilator support was provided temporarily . - pubmed
Twenty - five patients with epidermal cysts , which were 0.5 to 1.5 cm in diameter , non - inflamed , and freely movable , were treated . - pubmed
Helicobacter pylori and skin autoimmune diseases . - pubmed
In 150 patients with amnestic mild cognitive impairment , WMHs were quantified with the use of a semiautomated volumetric method . - pubmed
AIMS : We present an audit report and a systematic review of published observational studies on PIROLA occurrence in acute ischaemic stroke patients . - pubmed
METHODS : Clinical files of patients treated in the stroke unit of Bourg - en - Bresse General Hospital ( France ) from January 2010 to December 2012 were reviewed , and MEDLINE ( inception to May 2013 ) were searched and bibliographies / citations of retrieved articles examined for evidence of PIROLA . - pubmed
The systematic review identified 27 studies , totalising with ours , over 9050 acute ischaemic stroke patients from 12 countries , among whom 100 ( cumulative incidence rate : 17 % ; 95 % confidence intervals : 8 - 26 ) , developed a PIROLA within 6 - 240 minutes of receiving r - tPA , 0 - 100 % of them occurring among patients on ACEI . - pubmed
CONCLUSIONS : About 17 % acute ischaemic stroke patients receiving r - tPA develop PIROLA , occurring essentially among those on concomitant ACEI . - pubmed
Vibrio cholerae O1 , the causative agent of the disease cholera , has two biotypes namely the classical and El Tor . - pubmed
cholerae strains into biotype does not alter the clinical management of cholera but is of immense public health and epidemiological importance in identifying the source and spread of infection , particularly when V. - pubmed
METHODS : Overall survival of patients who had lobectomy for any stage non - small cell lung cancer without previous chemotherapy or radiation from 1996 to 2008 was evaluated using the Kaplan - Meier method and multivariate Cox analysis . - pubmed
Thoracotomy patients had larger tumors ( 3.9 + -2.3 versus 2.8 + -1.5 cm , p<0.0001 ) , and more often had higher stage cancers ( 50 % [ n=237 ] versus 71 % [ n=435 ] stage I , p<0.0001 ) compared with VATS patients . - pubmed
In a cohort of 560 patients ( 311 VATS , 249 thoracotomy ) who were assembled using propensity scoring and were similar in age , stage , tumor size , and sex , the operative approach did not impact survival ( p=0.5 ) , whereas increasing age ( HR 1.02 per year , p=0.01 ) , pathologic stage ( HR 1.44 per stage , p<0.0001 ) , and male sex ( HR 1.29 , p=0.01 ) predicted worse survival . - pubmed
Relation of epicardial fat to central aortic pressure and left ventricular diastolic function in patients with known or suspected coronary artery disease . - pubmed
We studied 134 consecutive patients undergoing left - sided cardiac catheterization for coronary artery disease ( CAD ) and examined the relation of epicardial fat volume measured by multi - detector computed tomography to ascending aortic pressure and LV ejection fraction determined by cardiac catheterization as well as indices of LV diastolic function assessed by Doppler echocardiography [ early diastolic mitral annular velocity ( e ' ) and a ratio of early diastolic mitral inflow to annular velocities ( E / e ' ) ] . - pubmed
UNLABELLED : Impaired tactile acuity in people with chronic pain conditions has been suggested to reflect altered cortical representation of the painful body part , and treatments that aim to improve tactile acuity in these conditions have shown clinical benefit . - pubmed
The aim of this review was to systematically evaluate the literature and use meta - analysis to establish whether tactile acuity is altered in people with chronic non - neuropathic pain . - pubmed
We systematically searched the literature for studies that investigated tactile acuity in people with chronic non - neuropathic pain and compared it to an appropriate control group . - pubmed
PERSPECTIVE : This systematic review synthesizes the evidence for tactile acuity deficits in people with chronic non - neuropathic pain . - pubmed
Many researchers have explored the effects of perinatal programming on the human neurodevelopment , and some aspects of the brain structure and/or functioning ( such as cognitive function , physiological reactivity to stress , and the risk for behavioral disorders or psychopathology ) were shown to be modifiable by the exposure to certain adverse events early in life such as neonatal infections , exposure to gestational psychosocial stress , nutrition during gestation , exposure to drugs , or tobacco smoking during pregnancy . - pubmed
OBJECTIVE : To develop a decision analytic model to calculate outcomes after treatment of cerebral aneurysms in elderly patients . - pubmed
PURPOSE : This cross - sectional study aimed to estimate the prevalence of Chlamydia trachomatis ( CT ) infection alone and in combination with human papillomavirus ( HPV ) . - pubmed
Furthermore , the study investigates whether the CT infection increases the risk of contracting HPV and whether the presence of both pathogens is associated with a higher prevalence of cervical lesions . - pubmed
The higher prevalence of LSIL in women co - infected with HPV and CT is possibly due to HPV . - pubmed
CONCLUSION : CT infection was more prevalent in younger women aged up to 32 years , who had an early onset of reproductive activity and a history of having had multiple sexual partners lifelong may be at a greater risk of acquiring infection of the genital tract by C. - pubmed
PATIENT SAMPLE : All patients who underwent palliative surgery for the treatment of a neoplastic spine lesion in our institution between 2005 and 2012 . - pubmed
OUTCOME MEASURES : Percentage of patients who underwent surgery as an emergency for acute fracture or rapid neurological decline . - pubmed
METHODS : We retrospectively reviewed the data of all patients who underwent palliative surgery for the treatment of a neoplastic spine lesion from solid cancer or multiple myeloma , in our institution between January 2005 and December 2012 . - pubmed
The cancer was known for 224 patients , while the lesion revealed the disease for the other 93 patients . - pubmed
The percentage of patients with known cancer operated as an emergency in our institution decreased significantly between 2005 and 2012 ( p = 0.0006 ) . - pubmed
Compound 4 exhibited cytotoxicity against the cervical carcinoma cell line ( CaSki ) with an IC50 value of 2.4 muM , and 6 showed toxicity toward brine shrimp Artemia salina with an LC50 value of 2.0 muM. - pubmed
Patients may also have questions regarding complementary and alternative medicines , so clinicians should know which options are most promising for patients with MS . - pubmed
The spread of dengue fever depends mainly on the availability of favourable breeding sites for its mosquito vectors around human dwellings . - pubmed
Here we tested on Genetic Absence Epilepsy Rats from Strasbourg ( GAERS ) the consequences of acute and chronic exposure to caffeine on the expression of spike - and - wave discharges ( SWDs ) . - pubmed
In elderly or comorbid patients diagnosed with small renal masses , competing cause mortality seems to exceed cancer - specific mortality at short- and intermediate - term follow up . - pubmed
According to the current available evidence , active surveillance is a safe and reasonable option for patients with renal tumors & lt;=4 cm ( cT1a ) and short life expectancy . - pubmed
Renal tumor biopsy is useful in the clinical work - up of patients who are candidates for active surveillance , in order to improve patient selection based on tumor histological characterization . - pubmed
Despite the proof of safety offered by expectant management for small renal masses in selected patients , further prospective studies with longer follow up are required in order to confirm the indications and long - term oncological outcomes of active surveillance protocols for renal tumors . - pubmed
Coronary stent selection and optimal course of dual antiplatelet therapy in patients at high bleeding or thrombotic risk : navigating between limited evidence and clinical concerns . - pubmed
Fifty - nine preeclamptic patients , 60 healthy pregnant women and 56 healthy nonpregnant women were involved in this case - control study . - pubmed
It is well known that long - term exposure to arsenite leads to human skin cancer , but the underlying mechanisms of carcinogenesis remain obscure . - pubmed
In vivo wound healing activity of gels containing Cecropia pachystachya leaves . - pubmed
METHODS : The wound healing activity of the gels was evaluated for 21 days , using the excision model in rats followed by histopathological and histomorphometric analysis . - pubmed
Evaluation of Executive Functions in Patients With Childhood Absence Epilepsy . - pubmed
OBJECTIVE : The aim of this study was to evaluate the executive function of patients with typical absence epilepsy . - pubmed
CONCLUSION : Long - term risk for learning impairments , failure in executive abilities , and short - term memory and attention disorders can occur in children with absence epilepsy . - pubmed
RESULTS : A total of 44 ECM patients were included in our analysis . - pubmed
METHODS : Seventy - one cases of patients with diabetic foot ulcers and 53 cases of nondiabetic ulcers were enrolled . - pubmed
Lyme disease , West Nile virus ( WNV ) , and other vector - borne diseases were identified as priority emerging non - enteric zoonoses in Canada in a prioritization exercise conducted by public health stakeholders in 2013 . - pubmed
Lyme disease is emerging in Canada due to range expansion of the tick vector , which also signals concern for the emergence of human granulocytic anaplasmosis , babesiosis , and Powassan virus . - pubmed
Prolongation of atrio - ventricular node conduction in a rabbit model of ischaemic cardiomyopathy : Role of fibrosis and connexin remodelling . - pubmed
Only one type of HPV was detected in 87.7 % of the E6 / E7 mRNA positive cases . - pubmed
Are aerobic interval training and continuous training isocaloric in coronary artery disease patients ? - pubmed
Chronic Kidney Disease , But Not Diabetes , Can Predict 30 - Day Outcomes in Patients with ST - Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention : A Single - Center Experience . - pubmed
BACKGROUND : Patients with acute coronary syndrome and impaired renal function have been shown to have high mortality . - pubmed
METHOD : This study enrolled 512 STEMI patients who received primary percutaneous coronary intervention . - pubmed
Patients were divided into 4 groups including group 1 : patients without DM or CKD ( nDM - nCKD ) ; group 2 : patients with DM but without CKD ( DM - nCKD ) ; group 3 : patients with CKD but without DM ( nDM - CKD ) ; group 4 : patients with DM and CKD ( DM - CKD ) . - pubmed
RESULTS : The patients in both the nDM - CKD group and DM - CKD group had higher incidences of hypotension , intra - aortic balloon counterpulsation use , and respiratory failure ( p & lt ; 0.005 ) . - pubmed
The patients with CKD stage 3 and 4 had longer hospital stay and higher 30 - day mortality rates ( p & lt ; 0.001 ) . - pubmed
CONCLUSIONS : STEMI patients with impaired renal function , but not DM , had significantly longer hospital stay and higher 30 - day mortality rates . - pubmed
Influence of Statin Pretreatment on Initial Neurological Severity and Short - Term Functional Outcome in Acute Ischemic Stroke Patients : The Fukuoka Stroke Registry . - pubmed
This study aimed at determining these associations in ischemic stroke patients . - pubmed
METHODS : Among patients registered in the Fukuoka Stroke Registry from June 2007 to October 2014 , 3,848 patients with ischemic stroke within 24 h of onset , who had been functionally independent before onset , were enrolled in this study . - pubmed
The frequency of mild neurological symptoms was significantly higher in patients with pre - stroke statin treatment ( 64.1 % ) than in those without the treatment ( 58.3 % , p & lt ; 0.01 ) . - pubmed
Sensitivity analysis in patients with dyslipidemia ( n = 1,998 ) also showed the same trend between pre - stroke statin treatment and mild neurological symptoms ( multivariable - adjusted OR 1.26 ; 95 % CI 0.99 - 1.62 ; p = 0.06 ) . - pubmed
Continuation of statin treatment , however , was significantly associated with favorable functional outcome among patients with pre - stroke statin treatment ( multivariable - adjusted OR 2.17 ; 95 % CI 1.16 - 4.00 ; p = 0.02 ) . - pubmed
CONCLUSIONS : Pre - stroke statin treatment in ischemic stroke patients was significantly associated with mild neurological symptoms within 24 h of onset . - pubmed
Pre - stroke statin treatment per se did not significantly influence the short - term functional outcome ; however , continuation of statin treatment during the acute stage of stroke seems to relate with favorable functional outcome for patients with pre - stroke statin treatment . - pubmed
Severe cytokine release syndrome ( sCRS ) and grade & gt;=3 neurotoxicity were observed in 13 and 28 % of all patients , respectively . - pubmed
We demonstrate how measurement of changes in tissue density with DHM , based on refractive index measurement , can quantify inflammatory alterations , without staining , in different layers of colonic tissue specimens from mice and humans with colitis . - pubmed
All patients admitted to Christian Medical College and Hospital , Ludhiana , who received a permanent pacemaker for bradyarrhythmias were included in the study . - pubmed
During the entire study period death occurred in 7.1 % patients . - pubmed
BACKGROUND : Early cardiac surgery may have a trade - off between stabilized hemodynamics with controlled infection and a risk of peri - operative death in patients with infective endocarditis ( IE ) complicated with cardio - embolic strokes . - pubmed
METHODS : We retrospectively studied clinical characteristics and outcomes in 68 consecutive patients with IE ( mean age , 58 + -3years , 62 % male ) who admitted in our institute during June 2013 and August 2015 . - pubmed
RESULTS : Cardio - embolic strokes were noted in 37 % of patients ( n=25 ) with IE and overall in - hospital mortality was 4 times higher in IE with cardio - embolic strokes than IE with an absence of strokes ( n=43 ) ( 20 % vs. 4.7 % , p=0.045 ) . - pubmed
Bacteremia of Staphylococcus aureus ( p=0.021 ) and a complication of cardio - embolic strokes ( p=0.031 ) were independently associated with in - hospital death in those with IE . - pubmed
The assessment of seafarers ' knowledge , attitudes and practices related to STI / HIV / AIDS in northern Morocco . - pubmed
Neutrophils , an important type of human immune cells , are involved in host defense against infections . - pubmed
[ Evaluation and treatment of sleep problems in children diagnosed with attention deficit hyperactivity disorder : an update of the evidence ] . - pubmed
INTRODUCTION : Attention deficit hyperactivity disorder ( ADHD ) affects approximately 5 % of all children and adolescents , and these patients frequently suffer from sleep problems . - pubmed
DEVELOPMENT : Sleep problems in children with ADHD include altered sleep and specific disorders per se or that may be due to comorbid psychiatric disorders or to the stimulants they receive as treatment for their ADHD . - pubmed
Today , an evaluation of the sleep conditions in children with ADHD is recommended before starting pharmacological treatment . - pubmed
Atomoxetine and melatonin are therapeutic alternatives for children with ADHD and more severe sleep problems . - pubmed
CONCLUSIONS : It is important to evaluate sleep in children who present symptoms suggestive of ADHD , since problems during sleep can play a causal role or exacerbate the clinical features of ADHD . - pubmed
Correct evaluation and treatment of sleep disorders increase the family 's and the child 's quality of life and can lessen the severity of the symptoms of ADHD . - pubmed
METHODS : This retrospective study was performed on 26 patients with muscle herniation confirmed by surgery . - pubmed
Much current TB vaccine research focuses on engineering live mycobacteria to interfere with phagosome biology and host intracellular pathways including apoptosis and autophagy , with candidates such as BCG Deltazmp1 , BCG DeltaureC::hly , BCG::ESX-1Mmar , Mtb DeltaphoP DeltafadD26 , Mtb DeltaRD1 DeltapanCD and M. - pubmed
It can be concluded that the dose of enrofloxacin used in the present study can be administered to contain infections caused by P. - pubmed
Highly pathogenic influenza viruses pose a serious public health threat to humans . - pubmed
PRESENTATION OF CASE : A 62 - year - old man with a two - day history of epigastric pain was admitted at emergency department . - pubmed
Simultaneous handling of celiac axis stenosis is still prone to controversy : no relapse of aneurysm have been reported in patients with celiac axis stenosis at long - term follow - up , simultaneous treatment should be reserved when angiography is alarming for likely hepatic or duodenal ischemia . - pubmed
Experiments with the newly synthesized fluorescent dye 1 - N - methylamino-5 - isocyanonaphthalene ( MICAN ) served to test its cytotoxicity on human HaCaT keratinocyte cell cultures . - pubmed
Comparative Metabolomics Elucidates Postprandial Metabolic Modifications in Plasma of Obese Individuals with Metabolic Syndrome . - pubmed
This study investigated the dynamic metabolic profile shift following the ingestion of low - fat milk or an isocaloric volume of rice milk in obese individuals with metabolic syndrome ( MetS ) . - pubmed
The comprehensive time - course metabolic profiling in MetS participants indicated that the postprandial metabolic profiles distinguish low - fat milk and rice milk consumption in a time - dependent manner . - pubmed
Nutrient deficiency promotes male - biased apparent sex ratios at the ramet level in the dioecious plant Myrica gale var . - pubmed
Retrospective evaluation of a decision - support algorithm ( MIPOGG ) for genetic referrals for children with neuroblastic tumors . - pubmed
A challenge for clinicians is the identification of children with neuroblastoma who require genetics evaluation for underlying cancer predisposition syndromes ( CPS ) . - pubmed
OBJECTIVES : A recent randomized study of fractionated radiation therapy ( RT ) examining 44 subtotally resected / recurrent benign meningioma patients revealed that at median follow - up of 17.1 years , the risk of stroke following proton - photon RT was 20.5 % ; the average stroke developed 5.6 years following RT completion ( Sanford et al . - pubmed
RESULTS : Fourteen studies met inclusion criteria ; 1431 patients received photon - based SRS for meningioma with a sufficient long - term follow - up . - pubmed
CASE REPORT A 30 - year - old man with multiple admissions for chronic intermittent colicky abdominal pain since childhood , was admitted for symptoms suggestive of proximal small bowel obstruction . - pubmed
The patient was administered imatinib for 2 months , which caused the tumor to shrink , and extended left lobectomy was performed . - pubmed
RESULTS : The survival experience of 2493 TB patients was investigated 73.7 % of which were pulmonary type . - pubmed
The incidence rate of death among patients during the treatment courses was 0.99 ( 95 % confidence interval : 0.84 - 1.1 ) per 100 person - months . - pubmed
Controlling the confounders , the incidence ( 95 % confidence interval ) of death was significantly higher among men ( HR=1.8 ; 1.2 - 2.6 ) , diabetic patients ( HR=1.7 ; 1.2 - 2.6 ) , cancerous patients ( HR=4.8 ; 2.6 - 8.8 ) and HIV positive patients ( HR=22.1 ; 7.3 - 66.4 ) . - pubmed
These goats were brought to the Kafkas University Wildlife Rescue and Rehabilitation Center ( Kars , Turkey ) for various reasons such as traffic accidents or firearm injury , but either could not be saved or were euthanized . - pubmed
Preventive Effects and Mechanisms of Garlic on Dyslipidemia and Gut Microbiome Dysbiosis . - pubmed
Taken together , our data demonstrated that whole garlic supplementation could meliorate the HFD - induced dyslipidemia and disturbance of gut microbiome . - pubmed
These findings reveal novel mechanisms controlling myocardial remodeling and may provide new clues for strategies to interfere cardiac remodeling - related heart disorders in humans . - pubmed
Water maze was conducted to evaluate spatial learning and memory ability of middle cerebral artery occlusion ( MCAO ) rats . - pubmed
Patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy ( CADASIL ) can develop multiple border - zone infarcts due to hypotension , hypovolemia , or surgery . - pubmed
We report the case of a 41 - year - old woman with CADASIL who developed multiple border - zone infarcts due to influenza A virus infection . - pubmed
Our case demonstrates that infectious conditions such as influenza A can trigger multiple border - zone infarctions in patients with CADASIL . - pubmed
MATERIAL AND METHODS : 40 patients with vulvar cancer and SLNB between 2008 and 2018 were retrospectively reviewed . - pubmed
Subsequently , long - term patient follow - up was performed with analysis of complications , relapse and mortality . - pubmed
In 3 out of 25 patients with lateral tumour lesions drainage was bilateral and in 2 out of 15 with midline lesions drainage was unilateral . - pubmed
Phenotypical and functional abnormalities of circulating neutrophils in patients with beta - thalassemia . - pubmed
Patients with beta - thalassemia present variable clinical severity ranging from asymptomatic trait to severe transfusion - dependent anemia and multiple organs complications . - pubmed
Despite some abnormalities reported for thalassemia patient 's immune system , few data exist on the characterization of human neutrophils in beta - thalassemia . - pubmed
The aim of this study was to investigate the phenotype and function of circulating neutrophil subsets in patients with beta - thalassemia major and with beta - thalassemia intermedia divided in transfusion - dependent and non - transfusion - dependent . - pubmed
By determining Pearson 's correlation coefficient and using StarBase , DIANA - LncBase , and Human MicroRNA Disease Database ( HMDD ) , the AD immune - related ceRNA network was generated . - pubmed
It can easily penetrate into tumor tissues , target an epitope inaccessible to mAb and be manufactured in bacteria for a low cost . - pubmed
They also bound to the three different human cancer cell lines , but not to the two cell lines as negative controls . - pubmed
Two of them were tested for their anti - tumor effect in vivo and showed the anti - tumor activity in a mouse xenograft model for human lung cancer . - pubmed
They could be potential therapeutics for the treatment of different human cancers . - pubmed
Oral anti - mycobacterial treatment of Crohn ' s disease ( CD ) is limited by the low aqueous solubility of drugs , along with the altered gut conditions of patients , making uncommon their clinical use . - pubmed
Permeability across Caco-2 cell monolayers and cytotoxicity and uptake in human macrophages was also determined . - pubmed
METHODS : We recruited 94 participants : 50 with TBI only ( TBI - only ) and 44 with TBI and PNES ( TBI + PNES ) . - pubmed
Participants completed mood ( Beck Depression Inventory - II ) , anxiety ( Beck Anxiety Inventory ) , and posttraumatic stress disorder ( PTSD ) symptom ( PTSD Checklist - Specific Event ) assessments before undergoing functional magnetic resonance imaging during an acute psychosocial stress task . - pubmed
Association of sleep - disordered breathing and wound healing in patients with diabetic foot ulcers . - pubmed
However , whether SDB has an adverse impact on wound healing in patients with diabetic foot ulcers ( DFUs ) is uncertain . - pubmed
The purpose of this study was to investigate the association of SDB with wound healing in patients with DFUs . - pubmed
METHODS : A total of 167 patients with DFUs were enrolled between July 2013 and June 2019 at West China Hospital to assess the association of SDB with wound healing , ulcer recurrence , and all - cause mortality . - pubmed
CONCLUSIONS : SDB is highly prevalent in patients with DFUs but its severity , as conventionally measured by AHI , is not associated with wound healing . - pubmed
Sleep fragmentation and hypoxemia are stronger predictors of poor wound healing , high ulcer recurrence and increased risk of death in patients with DFUs . - pubmed
Arteriolar hyalinosis is related to rapid GFR decline and long - standing GFR changes observed on renal biopsies in normo - microalbuminuric type 2 diabetic patients . - pubmed
METHODS : We evaluated 22 type 2 diabetic patients with normo- or microalbuminuria who took part in the previous study , to clarify which renal histological factors were associated with changes in UAE and the glomerular filtration rate ( GFR ) during 11.0 + - 3.0 years of follow - up . - pubmed
The GFR at follow - up in patients with IAH > = 2.0 was significantly decreased from baseline ( p = 0.042 ) and significantly lower than that of the patients with IAH < 2.0 ( p = 0.026 ) , which did not decrease significantly from baseline . - pubmed
The auditory system appears particularly sensitive , as previous work has shown that developmental PCB exposure causes both hearing loss and gross disruptions in the organization of the rat auditory cortex . - pubmed
PURPOSE : Primarily , to investigate the effect of high intake of cod ( lean fish ) or salmon ( fatty fish ) on serum concentration of total neopterin , a marker of cellular immune activation that is associated with cardiovascular disease . - pubmed
METHODS : In this randomised clinical trial , 63 participants with overweight / obesity consumed 750 g / week of either Atlantic cod ( N = 22 ) or Atlantic salmon ( N = 22 ) or were instructed to continue their normal eating habits but avoid fish intake ( Control group , N = 19 ) for 8 weeks . - pubmed
The purpose is to compare clinical outcomes and complication rates after surgery in patients with shoulder arthropathy treated with stemless or conventional stemmed shoulder prosthesis . - pubmed
Thirty patients with mild to severe essential hypertension satisfactorily controlled by twice - daily sotalol therapy entered a double - blind , crossover study comparing the efficacy , tolerability , and safety of their usual twice - daily sotalol administration with the same dosage given once daily . - pubmed
Brain proteins were analyzed in supra- and infratentorial structures of 6 patients dying from liver failure . - pubmed
An equal number of patients , lacking any evidence of liver disease or neurological disorder , served as controls . - pubmed
This report describes the results of language therapy initiated 1 to 6 years after the onset of aphasia in 14 patients . - pubmed
Similar results were obtained in experiments with brain extracts from patients with subacute sclerosing panencephalitis . - pubmed
Effects of mild physical activity , atenolol and the combination on ambulatory blood pressure in hypertensive subjects . - pubmed
DESIGN AND METHODS : In 12 hypertensive subjects ( mean age : 40.3 years ) a prospective randomized Latin square - design trial was performed with three treatments : physical training and placebo tablets ; atenolol 50 mg once a day and inactivity ; and physical training and atenolol 50 mg once a day . - pubmed
Relapse factors during maintenance therapy of acute lymphoblastic leukemia in children . - pubmed
The risk of infectious complication in our adolescent population prompted a recommendation for aggressive preventive measures , including documentation of recent negative cultures for Neisseria gonorrhoeae and Chlamydia . - pubmed
Reinduction of melatonin production by isoproterenol ( 2 mg / kg body weight ) administration to acutely light - exposed animals during late darkness was prevented by cycloheximide , but not by actinomycin D administration . - pubmed
Incessant monomorphic ventricular bigeminy was studied in a young patient with no organic heart disease . - pubmed
It arose in a 62 year old man and was diagnosed on the basis of a bilateral pleural effusion , which showed many plasma cells and plasmoblasts . - pubmed
The patient also presented multiple osteolytic lesions , no adenopathies , or signs of hepatic or splenic infiltration . - pubmed
Experimental results were correlated with postoperative catheterization data from 19 patients with tricuspid atresia who had the Fontan operation . - pubmed
Encephaloborreliosis is described in a 16 year old patient . - pubmed
Perineal hernia repair in the dog by transposition of the internal obturator muscle . - pubmed
A modified technique for transposition of the internal obturator muscle was used to repair perineal hernias in 100 dogs . - pubmed
Trifluoperazine does not affect doxorubicin cardiotoxicity in the rat . - pubmed
Analgesic effect and bioavailability of oral ketogan given as tablets or mixture to patients with chronic pain of malignant origin . - pubmed
Thirteen cancer patients with moderate to severe chronic pain of malignant origin on treatment with Ketogan tablets were included in an open non - randomized cross - over study comparing the analgesic effect , side effects and serum concentrations of Ketogan tablets and mixture . - pubmed
Circulating lymphocyte populations and autoantibodies in non - obese diabetic ( NOD ) mice : a longitudinal study . - pubmed
Several previous observations indicate a role for the immune system in the pathogenesis of insulin - dependent diabetes mellitus ( IDDM ) in non - obese diabetic ( NOD ) mice . - pubmed
In order to assess the status of the immune system in this model of spontaneous diabetes we studied the phenotype of circulating lymphocytes and the humoral autoimmunity to islet cells in non - diabetic NOD mice at various ages . - pubmed
Lymphocyte numbers were low in young NOD mice ( age less than 160 days ) as compared with other strains of mice and increased later to reach values in or above the range of controls . - pubmed
Antibodies to surface antigens of rat insulinoma cells were virtually absent in young NOD mice ( 75 - 100 days ) and appeared in 33 to 43 % of the samples from 150 to 185 days old NOD mice . - pubmed
The subjects were 97 chronic prostatitis patients for whom the prostate fluid had been confirmed to contain at least 30 leukocytes per 400 - power magnification field . - pubmed
In 53.9 % of the patients who had not been receiving therapy prior to inclusion in this study , the subjective symptoms consisted of urethral irritation or irritation upon urination . - pubmed
Magnetic resonance imaging of chronic myocardial infarcts in man . - pubmed
To evaluate the magnetic resonance imaging ( MRI ) features of chronic myocardial infarction ( MI ) , 22 patients and several normal volunteers were studied with a 0.35 - T cryogenic imaging system . - pubmed
At least one abnormality indicative of prior infarction was demonstrated on MRI in 20 of the 22 patients . - pubmed
Wall thinning was seen in 20 patients ; in six of these , the thinning resulted in aneurysm formation . - pubmed
[ Systemic lupus erythematosus and anti - native - DNA antibodies measured using Crithidia luciliae ] . - pubmed
Experimental studies on the spitting cobra ophthalmia ( Naja nigricollis ) . - pubmed
Structural polypeptides of the hamster strain of equine herpes virus type 1 : products associated with purification . - pubmed
[ Effect of intralienal oxygen injection in experimental traumatic shock on levels of phospholipid - P and total lipids in the blood serum in dogs ] . - pubmed
Purified Trypanosoma cruzi specific glycoprotein for discriminative serological diagnosis of South American trypanosomiasis ( Chagas ' disease ) . - pubmed
In a mouse model , the same test can differentiate between T cruzi and T rangeli infections . - pubmed
Requirement for membrane potential in Escherichia coli infection by phage T4 . - pubmed
The phage infection was strictly dependent on E. - pubmed
In one patient with a perforated peptic ulcer and tension pneumoperitoneum , an enormous increase in intra - abdominal pressure apparently led to acute aortic occlusion . - pubmed
The clinical findings of aortic occlusion were reproduced in a canine model by insufflation of air into the abdomen . - pubmed
[ Effect of aging on blood catecholamine under 3 conditions of sodium intake -- comparison between normal subjects and patients with essential hypertension ] . - pubmed
It is proposed that alternative mechanisms for hepatocyte injury may apply in different chronic HBV patients , one related to virus replication and one dependent on immunological factors . - pubmed
Posterior circulation in 82 children of " moyamoya " disease are studied . - pubmed
A distal splenorenal shunt was performed electively in 25 patients with bleeding oesophageal varices . - pubmed
During the follow - up period ( mean 41 months ) three patients died , one of liver insufficiency and two of cardiac complications . - pubmed
Two patients of 17 survivors ( 12 % ) had endoscopically demonstrable varices . - pubmed
Even though in certain patients the original selectivity of the shunt is lost it gives a good long - term variceal decompression and certainly is a useful alternative in the treatment of selected good risk patients for bleeding oesophageal varices . - pubmed
Macrophages obtained from rabbit lungs undergoing BCG - induced chronic inflammation released more chromium when incubated in the presence of phagocytosable particles than when incubated under resting conditions . - pubmed
Fifty consecutive spinal injury patients who underwent simultaneous EMG of the peri - urethral and perianal striated muscles along with cystometrogram on a multiple channel recorder are analysed . - pubmed
Work is in progress to improve the techniques and to evaluate the toxicity of the chemiluminescent material in animals . - pubmed
However , in 11/15 ( 73 % ) patients who underwent OGTT before and after surgery , an improvement in glucose tolerance was observed after tumor resection . - pubmed
We report herein the unusual case of a 25 - year - old man with CGL in whom gas gangrene developed , an association which has never before been encountered . - pubmed
Patients were grouped according to the presence ( n = 31 ) or absence ( n = 65 ) of multiple organ failure . - pubmed
The mortality rate in the patients who developed multiple organ failure was 42 % vs. only 2 % in those patients without multiple organ failure ( p & lt ; .0001 ) . - pubmed
Comparative characterization of antigenic epitopes in the immunodominant region of the protein encoded by open reading frame 3 in Burmese and Mexican strains of hepatitis E virus . - pubmed
To analyse the effect of strain - specific sequence variation on the antigenic properties of the protein encoded by the open reading frame 3 ( ORF 3 ) of hepatitis E virus ( HEV ) , two sets of short overlapping peptides spanning amino acids 91 to 123 of this protein from Burmese and Mexican strains were synthesized and tested with sera obtained from outbreaks of enterically transmitted non - A , non - B hepatitis in three different regions of the world ( Mexico , Turkmenistan and Kenya ) . - pubmed
Each patient was alert and free of injury to the globe when evaluated before surgery . - pubmed
Enrollment of patients with no light perception or who experienced delay between injury and treatment may be reasonably considered . - pubmed
Age - related therapeutic response to antithyroid drug in patients with hyperthyroid Graves ' disease . - pubmed
Recurrence after discontinuation of methimazole was more frequent in young than in aged patients . - pubmed
CONCLUSIONS : Aged patients with hyperthyroid Graves ' disease show a more favorable response to antithyroid drugs than young counterparts . - pubmed
A case of an adrenal incidentaloma in a 57 - year - old man with silent 21 - hydroxylase deficiency is reported . - pubmed
However , after surgical removal of the adrenal tumour , the patient developed acute adrenal insufficiency . - pubmed
Dideoxycytidine ( ddC ) is a nucleoside analogue active against human immunodeficiency virus and with in vitro activity against human hepatitis B virus . - pubmed
Accumulation of manganese and copper in pallidum of cirrhotic patients : role in the pathogenesis of hepatic encephalopathy ? - pubmed
Concentrations of zinc , copper and manganese were measured by atomic absorption spectrometry in samples of globus pallidus obtained at autopsy from 9 patients with chronic liver disease and an equal number of age - matched controls . - pubmed
Manganese concentrations were significantly increased several fold ( p & lt ; 0.01 ) in globus pallidus of liver disease patients accompanied by smaller but significant 2 - fold increases of copper . - pubmed
Increased pallidal manganese offers a cogent explanation for the observed T1 - weighted MRI signal hyperintensity in pallidum of cirrhotic patients . - pubmed
Basic research in Epstein - Barr virus ( EBV ) molecular genetics has provided means to maintain episomes in human cells , to efficiently deliver episomes with up to 150 kbp of heterologous DNA to human B lymphocytes , and to immortalize human B lymphocytes with EBV recombinants that can maintain up to 120 kbp of heterologous DNA . - pubmed
EBV - derived vectors are useful for experimental genetic reconstitution in B lymphocytes , a cell type frequently used in establishing repositories of human genetic deficiencies . - pubmed
In this study , the urinary free dopamine excretion ( uDA ) , delivery of L - dopa to renal proximal tubules ( plasma L - dopa x creatinine clearance ( Ccr ) ) , and the production of dopamine in the kidney [ uDA/(plasma L - dopa x Ccr ) ] were investigated in patients with congestive heart failure ( n = 30 ) and in normal controls ( n = 12 ) . - pubmed
From these findings , it was suggested that ( i ) uDA was clearly suppressed in patients with CHF , and ( ii ) the possible mechanisms of its suppression might be due to decrease of delivery of L - dopa into the proximal tubules and suppressed production of dopamine from L - dopa in the kidney . - pubmed
Opioids decrease the sympathetic and somatic responses to noxious stimulation and can be given in high doses without negative inotropic effects , even in patients with impaired cardiac function . - pubmed
The duration of action of remifentanil has been found to be short , even in patients with renal or hepatic failure , although only low doses have been used in the studies published to date . - pubmed
To test for this hypothesis house rats ( Rattus rattus ) were trapped at a waste disposal site and the levels of micronuclei and chromosomal aberrations determined . - pubmed
The results indicate that the frequency of chromosomal aberrations increases with the weight ( age ) of the animals , while micronuclei did not significantly differ from the level found in laboratory rats . - pubmed
We note a less pronounced weight dependent increase of chromosomal aberrations , most probably reflecting the different residence time at the waste disposal plant , an age dependent decrease of chromosomal aberrations of the F1 - generation housed in the animal facility , indicating that the offspring had been exposed transplacentally and an age independent level of chromosomal , aberrations in the F2 - generation not significantly different from that of the Fischer 344 laboratory rat . - pubmed
Zinc - bis - histidinate preserves cardiac function in a porcine model of cardioplegic arrest . - pubmed
METHODS : Domestic pigs ( 35 to 50 kg ) on left - sided cardiopulmonary bypass were subjected to 90 minutes of regional ischemia followed by 60 minutes of hypothermic cardioplegic arrest induced by antegrade infusion of 20 mL / kg cold St. Thomas ' # 2 cardioplegic solution with or without 100 mumol / L of zinc - bis - histidinate and maintained by infusion of 10 mL / kg of the same every 20 minutes . - pubmed
Fulminant cerebral oedema is an uncommon , fatal complication of diabetic ketoacidosis ( DKA ) in children . - pubmed
OBJECTIVE : To evaluate the ability of patients with chronic obstructive pulmonary disease ( COPD ) to accomplish 6 weeks of inspiratory muscle training ( IMT ) using a pressure threshold device , and to observe how the training affected inspiratory muscle strength and dyspnea . - pubmed
SUBJECTS : Four adults with severe COPD ( the mean of the forced expiratory volume in 1 second [ FEV1 ] was 28 % of predicted value ) . - pubmed
PURPOSE : ( a ) To compare weight change at 1 year between adolescents 13 - 19 years old who were using either depot medroxyprogesterone acetate ( DMPA ) or oral contraceptives ( OC ) , and ( b ) to determine if age , baseline body mass index ( BMI ) , race / ethnicity , or weight gain at 3 months predicted which subjects would gain excessive weight . - pubmed
When a patient is being evaluated for posterior shoulder pain and infraspinatus muscle weakness , electrodiagnostic studies are an essential part of the evaluation . - pubmed
The wild mouse ecotropic retrovirus , Cas - Br - E , induces progressive , noninflammatory spongiform neurodegenerative disease in susceptible mice . - pubmed
The frequency of three mitochondrial point mutations , 1555A-->G , 3243A-->G , and 7445A-->G , known to be associated with hearing impairment , was examined using restriction fragment length polymorphism ( RFLP ) analysis in two Japanese groups : ( 1 ) 319 unrelated SNHL outpatients ( including 21 with aminoglycoside antibiotic injection history ) , and ( 2 ) 140 cochlear implantation patients ( including 22 with aminoglycoside induced hearing loss ) . - pubmed
Epoetin alfa therapy effectively ameliorates the anemia of end - stage renal disease in pediatric dialysis patients and thus minimizes many of these negative effects . - pubmed
Results suggested that carbaryl , esfenvalerate , endosulfan , and deltamethrin had low residual and acute toxicity to P. - pubmed
In the endometrium from Norplant users with bleeding problems , in vitro supplementation of vitamin E resulted in a significantly higher angiogenic score than placebo . - pubmed
Although a highly significant reduction of bleeding days in both groups , vitamin E and placebo , was seen during the 2 months of the study , the number of bleeding days was significantly lower in women treated with vitamin E than with placebo . - pubmed
However , after inoculation with virulent virus the pig developed acute fatal ASF . - pubmed
The synthesized nucleosides were assayed against human immunodeficiency virus ( HIV ) and hepatitis B virus in human peripheral blood mononuclear ( PBM ) and 2.2.15 cells , respectively . - pubmed
6 - Amino-9 -[ 2,3 - dideoxy-3 - C -( hydroxymethyl )- 3 - C - methyl - beta - D - glycero - tetrofuranosyl ]- 2 - fluoropurine shows moderate antiviral activity ( EC50 = 2.55 microM ) against HIV-1 strains and 6 - amino-9 -[ 3 - deoxy-3 - C -( hydroxymethyl )- 3 - methyl - alpha - D - glycero - tetro furanosyl ]- 2 - fluoropurine exhibits potent anti - HIV activity ( EC50 = 0.073 microM ) with significant cytotoxicity ( IC50 = 1.0 microM ) . - pubmed
We report a case of WD with spinal presentation in an otherwise healthy woman who had a 5 - year history of relapsing - remitting cervico - thoracic myelopathy . - pubmed
OBJECTIVE : This study examined the metabolic effects of heart transplantation in patients in end - stage cardiac failure . - pubmed
The patients were selected from 480 transplant patients in whom there was a 6 % prevalence of type 2 diabetes . - pubmed
There was no significant difference in the 1992 AJCC stages pT2a vs pT2b ( P=0.1232 ) and the recurrence - free rate was not significantly different for patients with 1992 AJCC pT3a vs pT3b disease ( P=0.9 ) . - pubmed
Patients with infrequent attacks of supraventricular arrhythmia may benefit from self administration of antiarrhythmic drugs on an ' as required ' basis . - pubmed
PATIENTS : Nine newborns ( four boys , five girls ) were diagnosed with symptomatic vein of Galen malformations in the neonatal period during the period 1996 - 2001 . - pubmed
RESULTS : The immediate outcome after a series of endovascular procedures was control of cardiac failure and normal neurological function in six ( 66 % ) patients , one death from intractable cardiac failure in the neonatal period , and two late deaths with severe hypoxic - ischaemic neurological injury ( 33 % mortality ) . - pubmed
Clinical review at 6 months to 4 years of age showed five infants with no evidence of neurological abnormality or cardiac failure and one child with mild developmental delay ( 11 % ) . - pubmed
Systemic arterial vasodilators improve outcome in neonates with cardiac failure secondary to VGAM . - pubmed
A 74 - year - old patient with hypertension suddenly presented left unilateral ptosis and mastication disorders . - pubmed
Exercise training improves biventricular oxidative metabolism and left ventricular efficiency in patients with dilated cardiomyopathy . - pubmed
OBJECTIVES : The aim of this study was to determine the effect of exercise training on myocardial oxidative metabolism and efficiency in patients with idiopathic dilated cardiomyopathy ( DCM ) and mild heart failure ( HF ) . - pubmed
BACKGROUND : Exercise training is known to improve exercise tolerance and quality of life in patients with chronic HF . - pubmed
METHODS : Twenty clinically stable patients with DCM ( New York Heart Association classes I through III ) were prospectively separated into a training group ( five - month training program ; n = 9 ) and a non - trained control group ( n = 11 ) . - pubmed
Therefore , exercise training elicits an energetically favorable improvement in myocardial function and exercise tolerance in patients with DCM . - pubmed
The objective of the present study was to compare parameters associated with oxidative phosphorylation and the inner mitochondrial membrane potential of skeletal muscle of rats submitted to total ischemia in order to determine which mitochondrial alterations are mainly affected in this condition . - pubmed
MATERIAL AND METHODS : Wistar rats were submitted to 5 h total ischemia using the tourniquet method ( ischemic limb group ) . - pubmed
CONCLUSIONS : Five - hour total ischemia applied to rat skeletal muscle led to the inhibition of the mitochondrial respiratory chain ( represented by decreased state 3 and state 4 respiration rates ) . - pubmed
PURPOSE : We assessed the effects on spermatogenesis of placebo vs 10 or 20 mg tadalafil administered daily for 6 months to healthy men and men with mild erectile dysfunction . - pubmed
MATERIALS AND METHODS : In 2 studies 421 healthy men or men with mild erectile dysfunction who were 45 years or older and met semen criteria derived from WHO reference values were randomized to 6 months of treatment with placebo ( 101 ) or 10 mg tadalafil ( 103 ) , or to placebo ( 106 ) or 20 mg tadalafil ( 111 ) . - pubmed
[ Intravenous virus vaccine confers equal protection in experimental plague infection induced by three varieties of Pasteurella pestis ] . - pubmed
[ Transplantation of the teres major and latissimus dorsi in obstetrical paralysis of the arm in children ] . - pubmed
[ Blood protein picture in human and experimental mycoses ] . - pubmed
Benign paroxysmal positional vertigo in older women may be related to osteoporosis and osteopenia . - pubmed
Thirty - two women , whose ages ranged from 50 to 85 years ( median age , 69 years ) , who had BPPV and were free of any other otoneurologic history , were selected . - pubmed
The BPPV was unilateral in 26 patients and bilateral in 6 patients . - pubmed
Our results showed osteopenia or osteoporosis in 24 of the 32 patients ( 75 % ) with BPPV . - pubmed
The patients with BPPV had a significantly lower ( p & lt ; .026 ) T - score in all groups . - pubmed
Serosurvey of viral infections in free - ranging Namibian cheetahs ( Acinonyx jubatus ) . - pubmed
Cheetahs ( Acinonyx jubatus ) in captivity have unusually high morbidity and mortality from infectious diseases , a trait that could be an outcome of population homogeneity or the immunomodulating effects of chronic stress . - pubmed
To assess the extent to which free - ranging cheetahs are exposed to feline and canine viruses , sera from 81 free - ranging cheetahs sampled between 1992 and 1998 were evaluated for antibodies against canine distemper virus ( CDV ) , feline coronavirus ( feline infectious peritonitis virus ; FCoV/ FIPV ) , feline herpesvirus 1 ( FHV1 ) , feline panleukopenia virus ( FPV ) , feline immunodeficiency virus ( FIV ) , and feline calicivirus ( FCV ) and for feline leukemia virus ( FeLV ) antigens . - pubmed
Antibodies against CDV , FCoV / FIPV , FHV1 , FPV , and FCV were detected in 24 , 29 , 12 , 48 , and 65 % of the free - ranging population , respectively , although no evidence of viral disease was present in any animal at the time of sample collection . - pubmed
Dietary aluminium and renal failure in the koala ( Phascolarctos cinereus ) . - pubmed
The study is the first account where aluminium ingested as part of the natural diet of mammals has been shown to accumulate in the animal and be implicated with nephrotoxicity . - pubmed
Following the initiation of Metabolife 356 , the patient experienced four shocks over a 3 day period with two 30 J shocks being delivered sequentially . - pubmed
The aim of the study was to determine whether the cooling process of the organism in the presence of ethanol intoxication may be related to inhibition of the physiological mechanism of ketogenesis induced by hypothermia . - pubmed
The treatment of subtrochanteric nonunions with the long gamma nail : twenty - six patients with a minimum 2 - year follow - up . - pubmed
A new Coronavirus ( SARS - CoV ) is the aetiological agent of the severe acute respiratory syndrome ( SARS ) . - pubmed
Because of the critical role played by serological assays for SARS diagnosis , an in - house ELISA based on SARS - CoV recombinant antigens was developed . - pubmed
Abnormal sperm chromatin condensation is common in sterile men , and our results may provide insight into the molecular mechanisms underlying certain human infertility disorders . - pubmed
Seven patients underwent the procedure -- five with syringomyelia , one with a symptomatic perineurial cyst , and one with a large arachnoid cyst . - pubmed
Altered diaphragm muscle action potentials in Zucker diabetic fatty ( ZDF ) rats . - pubmed
The Zucker diabetic fatty ( ZDF ) rat is a model of type 2 diabetes , being characterized by obesity , diabetes , and dyslipidemia . - pubmed
These findings in ZDF rats contrast with type 1 diabetic rats , suggesting that isolated hyperglycemia differs from hyperglycemia combined with other metabolic perturbations with respect to diaphragm electrophysiological derangements . - pubmed
MATERIAL AND METHOD : A total of 63 asymptomatic patients with chronic renal failure ( CRF ) with regular hemodialysis were followed for 18 months for cardiac mortality , myocardial infarction events and interventional procedures such as percutaneous transluminal coronary angioplasty ( PTCA ) and coronary artery bypass graft ( CABG ) . - pubmed
Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia . - pubmed
We tested the hypothesis that hyperhomocysteinemia accelerates arterial thrombosis in mice . - pubmed
Female nude mice were subcutaneously implanted with human gastric cancer cells ( BGC823 ) for the tumor xenografts studies . - pubmed
In vivo , alphastatin sufficiently suppressed neovascularization of the tumor in the nude mice . - pubmed
Immunohistochemical studies of tumor tissues revealed decreased micro vessel density in alphastatin - treated animals as compared with controls . - pubmed
Enhanced lipid peroxidation and nitric oxide products with deranged antioxidant status in patients with head and neck squamous cell carcinoma . - pubmed
We conducted a study to evaluate the levels of lipid peroxidation products , nitric oxide ( NO ) products and antioxidants in patients with head and neck squamous cell carcinoma ( HNSCC ) . - pubmed
Fifty one HNSCC patients , 33 healthy tobacco smokers / chewers as tobacco user controls , and 37 non - smokers / chewers as normal controls were recruited for this study . - pubmed
Lipid peroxidation products , including lipid hydroperoxide ( LHP ) and malondialdehyde ( MDA ) , nitric oxide ( NO ) products , including nitrite ( NO ( 2 )(- ) ) , nitrate ( NO ( 3 )(- ) ) , and total nitrite ( TNO ( 2 )(- ) ) were found to be significantly elevated with a concomitant depletion of antioxidants in HNSCC patients as compared to tobacco users and normal controls . - pubmed
Prognostic implications of preoperative atrial fibrillation in patients undergoing aortic valve replacement : is there an argument for concomitant arrhythmia surgery ? - pubmed
RESULTS : Patients with preoperative AF presented with more severe congestive heart failure ( p = 0.03 ) and more often had significant tricuspid regurgitation ( p = 0.01 ) preoperatively . - pubmed
They also had worse late survival ( risk ratio [ RR ] for death = 1.5 , p = 0.03 ) with 1- , 5- , and 7 - year survival rates substantially reduced at 94 % , 87 % , and 50 % , respectively , for those in AF versus 98 % , 90 % , and 61 % for patients in sinus rhythm preoperatively . - pubmed
Individuals in AF had a greater probability of subsequent rhythm - related intervention ( RR = 4.7 , p = 0.0002 ) , and more frequently developed congestive heart failure ( 25 % vs 10 % , p = 0.005 ) and stroke ( 16 % vs 5 % , p = 0.005 ) . - pubmed
CONCLUSIONS : Performance of concomitant arrhythmia surgery in patients undergoing aortic valve surgery may reduce late morbidity ; however , its potential impact on late mortality in this high - risk subset of patients remains unclear . - pubmed
We therefore aimed in this study to investigate the effect of ID on BAEPs by comparing three groups of infants with ID , IDA and iron sufficiency ( control ) both before and after iron treatment ( in iron - deficient groups ) . - pubmed
To identify such targets , we screened cDNA libraries from human testis , lung and breast cancer , bovine and porcine muscle and wheat germ for reactivity with paraproteins in the sera from 115 patients with MGUS and MM . - pubmed
The broad spectrum of auto- , allo- and heteroantigens as targets of human paraproteins in patients without signs of chronic antigenic stimulation renders a causal role of the antigenic stimulus in the pathogenesis of MGUS and MM unlikely . - pubmed
Measurements were made in normal rats and in rats with arthritis induced in one knee by intraarticular injections of kaolin / carrageenan . - pubmed
Studies on Leptospira Infection in Rodents and Dogs in Columbia . - pubmed
There was evidence of decreasing prevalence of IPNV in mussels from Shetland once IPN outbreaks subsided , indicating they are an unlikely source of re - infection on farms . - pubmed
FINDINGS : The number of irreversible heel pressure ulcers was lower in the experimental ( 3 patients , 8.6 % ) than in the control group ( 19 patients , 55.4 % ) ( p<0.0001 ) . - pubmed
CONCLUSION : An anatomical foam body - support is effective in preventing heel pressure ulcers in patients on a medical intensive care unit and is well tolerated . - pubmed
[ Systemic inflammation and experimental cancer in a murine model ] . - pubmed
The link between cancer and inflammation in an organ or tissue has firmly been established on the basis that cancer tends to occur at sites of chronic inflammation and that local inflammatory processes can accelerate the growth of preexisting tumors in both animals and human beings . - pubmed
In mice bearing a large MC - C tumor , a high number of circulating PMN and myeloid precursors were evident . - pubmed
Microvascular ear reconstruction using a free radial forearm flap after dog bite . - pubmed
A 68 - year old woman suffered from a subtotal amputation of the left ear due to a dog bite . - pubmed
Twelve hours after the last injection , the animals were sacrificed by decapitation without anaesthesia . - pubmed
Effect of temperature on heart rate in diploid and triploid brook charr , Salvelinus fontinalis , embryos and larvae . - pubmed
The aim of this study was to determine whether heart rate differs between triploid and control ( diploid ) brook charr , Salvelinus fontinalis , at embryo - larval stages , when the heart is easily visible and the fish are relatively inactive . - pubmed
A herring gull neuronal cell culture method was used to determine the effects of PBDEs on cytotoxicity and mRNA expression . - pubmed
Patients with TACs often visit dental offices seeking relief for their pain . - pubmed
High prevalence and early complication of symptomatic vertebral fracture in elderly people treated with high - dose glucocorticoids . - pubmed
Hashimoto described four patients with goiter . - pubmed
Hypothyroid patients with Hashimoto ' s thyroiditis usually receive life - long l - thyroxine therapy . - pubmed
Patients who had Hashimoto ' s hypothyroidism and then Graves ' hyperthyroidism ( and vice versa ) , have also been reported . - pubmed
METHODS : Colitis was induced by trinitrobenzene sulfonic acid and ethanol in 30 rats under general anesthesia , and 10 rats were used as a sham group . - pubmed
Subsequent to induction of colitis , rats were divided into three groups ; budesonide group received 0.1 mg / kg budesonide , levobupivacaine group received 10 mg / kg levobupivacaine and saline group received 1 mL saline solution via rectal route for 7 d. In the sham group , only routine rectal catheterization was performed without use of any material . - pubmed
Antimitotic agents such as taxanes ( paclitaxel and docetaxel ) have greatly advanced the treatment of breast cancer , although variable patient response and drug toxicity are major limitations . - pubmed
However , mechanisms of curcumin - inhibited cell growth and -induced apoptosis in human non - small cell lung cancer cells ( NCI - H460 ) still remain unclear . - pubmed
One patient ( 4.3 % ) underwent secondary fusion surgery due to persistent pain . - pubmed
Population pharmacokinetics of ustekinumab in patients with active psoriatic arthritis . - pubmed
Patient body weight and antibody - to - ustekinumab status were significant covariates affecting the CL / F and/or V / F of ustekinumab . - pubmed
CONCLUSION : The pharmacokinetics of ustekinumab in patients with PsA are comparable to those in patients with moderate - to - severe plaque psoriasis which was previously investigated . - pubmed
For example , a reduced ability to masticate , such as that resulting from toothlessness or soft - diet feeding , causes learning and memory deficits in aged animals and pathologic changes in the hippocampus . - pubmed
Improved outcome after anesthesia with volatile anesthetics in non - cardiac surgical patients at risk of perioperative myocardial infarction has not been univocally demonstrated yet . - pubmed
METHODS : Human endothelial cell monolayers ( human umbilical vein endothelial cells ( HUVECs ) and human microvascular endothelial cells of the lung ( HMEC-1s ) ) were exposed to ROS production , after which electrical impedance , cellular integrity and tumour cell adhesion were investigated . - pubmed
Treatment of rats with the ROS scavenger edaravone prevented surgery - induced tumour cell adhesion and downregulation of tight junction proteins in the liver . - pubmed
In light of this , perioperative therapeutic intervention , preventing surgery - induced inflammatory reactions , may reduce the risk of developing liver metastases , thereby improving the clinical outcome of patients with colorectal cancer . - pubmed
OBJECTIVE : Septic shock heterogeneity has important implications for clinical trial implementation and patient management . - pubmed
Glioblastoma ( GBM ) , the most common primary brain tumor in adults , is one of the most aggressive human cancers associated with high mortality . - pubmed
However , almost all patients develop disease progression following this multimodal therapy . - pubmed
We investigated the effects of Fascioloides magna infection on the serum biochemistry values of the naturally infected red deer population in eastern Croatia . - pubmed
Further investigation of changes in liver enzymes and other serum metabolites in controlled , experimentally induced fascioloidosis in red deer is needed to better understand the pathogenesis of F. - pubmed
This product be used as a biodrug in maintaining the blood glucose level in diabetic patients . - pubmed
Compared with participants with a normal body mass index ( & lt;25 kg / m(2 ) ) , obese women ( & gt;=30 kg / m(2 ) ) had a 25 -( OH ) D level that was 17.8 nmol / L lower . - pubmed
Enterotoxigenic Escherichia coli ( ETEC ) is a major cause of diarrhoea in neonatal and postweaning pigs . - pubmed
F41 is one of ETEC fimbriae that adhere to the small intestinal epithelium and lead to development of diarrhoea . - pubmed
Patients waking up with stroke symptoms are generally excluded from intravenous thrombolysis . - pubmed
If positive the WAKE - UP trial is expected to change clinical practice and to make effective and safe treatment available for a large group of acute stroke patients currently excluded from specific acute treatment . - pubmed
No significant differences were found when comparing impairment , pain , patient satisfaction and disability . - pubmed
Allergy to citrus fruits is often associated with pollinosis and sensitization to other plants due to a phenomenon of cross - reactivity . - pubmed
The aims of the present study were to highlight the cross - reactivity among citrus and the major allergenic pollens / fruits , throughout clinical and molecular investigations , and to evaluate the sensitization frequency to citrus fruits in a population of children and adults with pollinosis . - pubmed
Neospora caninum is an important intracellular protozoan parasite with an affinity to the central nervous system of many animals and a major causative agent of repeated abortions in cattle . - pubmed
Further studies are needed with 123I - mIBG to assess its utility in patients with early cardiac autonomic neuropathy . - pubmed
The prevalence of any helminthic infection , Ascaris lumbricoides , Trichuris trichiura , and hookworm were 25.0 % , 18.2 % , 9.2 % , and 5.3 % , respectively . - pubmed
Hypertensive women , affected by APA , present urinary SB3 concentrations significantly higher than women affected by BAH . - pubmed
A 24 - year - old man was diagnosed with klinefelter ' s syndrome ( KS ) and his wife was found to have an inversion on chromosome 9 - 46 , XX , inv ( 9 ) ( p11q21)- because of infertility . - pubmed
Desmopressin orally disintegrating tablet in Japanese patients with central diabetes insipidus : a retrospective study of switching from intranasal desmopressin . - pubmed
Patients with CDI have been successfully treated with desmopressin administered either by intranasal instillation or oral tablets . - pubmed
We conducted a retrospective single - center study of 15 Japanese CDI patients treated with desmopressin ODT therapy , which aimed to evaluate the efficacy and safety of switching to desmopressin ODT and to analyze the clinical factors that affect the desmopressin ODT dose in Japanese patients . - pubmed
In conclusion , desmopressin ODT was safe and effective in the treatment of Japanese adult CDI patients . - pubmed
Correlation between Microalbuminuria and Hypertension in Type 2 Diabetic Patients . - pubmed
BACKGROUND : Hypertension is commonly found in patients with Diabetic Kidney Disease ( DKD ) . - pubmed
Microalbuminuria is the first clinical sign of involvement of kidneys in patients with type 2 diabetes . - pubmed
OBJECTIVES : To determine the correlation between microalbuminuria and hypertension and their association with other risk factors in type 2 diabetic patients . - pubmed
METHODS : One hundred and thirteen type 2 diabetic patients attending the diabetic clinic of Shaikh Zayed Postgraduate Medical Institute , Lahore , Pakistan were screened for microalbuminuria and raised blood pressure . - pubmed
Group 2 patients showed higher blood pressure values as compared to Group 1 . - pubmed
So , early recognition of renal dysfunction through detection of microalbuminuria and to start treatment without any delay will confer future protection from end stage renal disease as well as hypertension and its complications in type 2 diabetic patients . - pubmed
Many of these were acute - phase response proteins , previously reported to be increased in depressed patients . - pubmed
High intake of staples , especially rice , was positively associated with endometrial cancer . - pubmed
BACKGROUND : Based on results of the PLATO ( Platelet Inhibition and Patient Outcomes ) trial comparing ticagrelor with clopidogrel therapy , the U.S. Food and Drug Administration approved ticagrelor in 2011 for reducing thrombotic cardiovascular events in patients with acute coronary syndrome ( ACS ) with the proviso that it be taken with low - dose aspirin . - pubmed
The aim of the study was to assess the quality of life amongst patients with morbid obesity as well as the impact of bariatric treatment on body weight and obesity - related diseases in addition to conducting an analysis of changes in the quality of life after surgical treatments , in the context of the surgical procedure type and degree of body weight loss . - pubmed
MATERIAL AND METHODS : Sixty - five patients were treated for morbid obesity . - pubmed
Women during the third trimester of pregnancy and children at ages 3 and 5 years provided spot urine samples . - pubmed
The recent clinical success of immunotherapy in the treatment of certain types of cancer has demonstrated the powerful ability of the immune system to control tumor growth , leading to significantly improved patient survival . - pubmed
Clinical data of examined patients and imaging findings in terms of description of the hepatic parenchyma and the presence of BFLL , were recorded . - pubmed
The mice were treated with QL for three days before surgery and continually after I / R. Triphenyltetrazolium chloride staining , echocardiography and Masson 's trichrome staining were used to determine infarct size , cardiac function , and fibrosis , respectively . - pubmed
RESULTS : At 1 day after I / R , QL treatment significantly reduced the infarct size of mice exposed to I / R. At 7 days after I / R , mortality was reduced in QL treated animals in comparison with the control group . - pubmed
In addition , QL treated mice showed increased left ventricular ejection fraction ( LVEF ) and left ventricular fractional shortening ( LVFS ) at 1 and 7 days after I / R. In agreement , Masson 's trichrome staining demonstrated that interstitial fibrosis was less pronounced in QL treated mice compared with controls , suggesting that adverse left ventricular remodeling is attenuated in QL treated mice . - pubmed
In vivo antitumor study also substantiated the dramatically enhanced efficacy of DTX / Ac - betaCD NPs in a melanoma - bearing nude mouse model . - pubmed
We found robust sprouting of uninjured corticospinal and serotonergic fibers in a rat cervical hemisection SCI model . - pubmed
A mouse pyramidotomy model was used to confirm that this robust sprouting was not species or injury model specific . - pubmed
We found robust sprouting of uninjured corticospinal and serotonergic fibers in a rat hemisection spinal cord injury model . - pubmed
Long - term benefit of liposuction in patients with lipoedema : a follow - up study after an average of 4 and 8 years . - pubmed
BACKGROUND : Long - term results following liposuction in patients with lipoedema are available only for an average period of 4 years . - pubmed
METHODS : In a single - centre study , 85 patients with lipoedema had already been examined after 4 years . - pubmed
CONCLUSION : These results demonstrate for the first time the long - lasting positive effects of liposuction in patients with lipoedema . - pubmed
METHODS : A retrospective review of children aged up to 17 years who had surgery for intussusception at this institution between 1 January 2004 and 31 December 2013 . - pubmed
RESULTS : The cohort of 44 individuals ( 18 females ) presented at a median age of 9 months ( range 2.5 months-15.75 years ) with intussusception ; 36 patients had undergone a failed pneumatic reduction . - pubmed
Conversion was required in 13 individuals : inability to reduce a ' tight ' intussusception in seven individuals , limited working space in four individuals , and inadequate tactile response in two individuals . - pubmed
An open approach was chosen for seven individuals at a median age of 5 ( range 4 - 11 ) months : three individuals had marked abdominal distension , two individuals had a pneumoperitoneum and two individuals presented with a large central mass . - pubmed
Methods The study included 50 bladder cancer patients , 50 with urinary tract infection and 51 healthy volunteers . - pubmed
This parameter also increases in serum and urine of cases with urinary tract infection . - pubmed
This article describes a patient with atraumatic multifocal intracerebral , subarachnoid , and bilateral frontal convexity acute subdural hematomas . - pubmed
The patient is a 46 - year - old Caucasian man who presented with a spontaneous severe progressive headache . - pubmed
Felis catus papillomavirus type 2 ( FcaPV2 ) DNA is found in feline cutaneous squamous cell carcinomas ( SCCs ) ; however , its biological properties are still uncharacterized . - pubmed
Clinical phtorejuvenation effect was also evaluated from nine patients who had PDT to treat actinic keratoses . - pubmed
BACKGROUND : Porcine wounds closely mimic human wounds and are often used experimentally in burn studies . - pubmed
The burn injury was inflicted by preheating the burn device to 100 C and pressing on the dorsum of pig skin for different time points ranging from 5 to 30s using standardized force of 10N on the device . - pubmed
CONCLUSION : The authors describe a simple , standardized and reproducible animal burn model using a customized burn device . - pubmed
A study of the free radical scavenging effects of Piper betle leaf extract in patients with vitiligo . - pubmed
METHODS : The effect of Piper betle on the generation of reactive oxygen species in erythrocytes was measured by flow cytometry in patients with active and stable vitiligo versus healthy controls , using 5 -( and-6 )- chloromethyl-2 '- 7 '- dichlorodihydrofluorescein diacetate . - pubmed
RESULTS : The generation of reactive oxygen species in erythrocytes was higher in patients with vitiligo ( n = 23 ) compared to healthy controls ( n = 18 ) . - pubmed
The levels of reactive oxygen species were higher in patients with active vitiligo . - pubmed
Treatment of erythrocytes with Piper betle in concentrations of 0.5 and 1.0 mug / ml significantly decreased the baseline levels of reactive oxygen species by 31.7 % in healthy controls , and 47.6 % and 44.3 % in patients with active vitiligo , respectively . - pubmed
Piper betle effectively scavenged hydrogen peroxide , which was evident by a decrease in the geometrical mean fluorescence channel by 52.4 % and 62.9 % in healthy controls , and 45.0 % and 57.0 % in patients with active vitiligo . - pubmed
CONCLUSION : This pilot study indicates that patients with active vitiligo demonstrate enhanced generation of reactive oxygen species in erythrocytes , which was significantly reduced following ex vivo treatment with Piper betle . - pubmed
While the total amount of left - atrial adipose tissue was higher in the sheep with AF , no changes in regional coverage were observed . - pubmed
Objectives : The aims were to assess the prevalence of malnutrition and to validate bioelectrical impedance analysis ( BIA ) against whole - body DXA for the assessment of body composition in patients with SSc . - pubmed
Fiber - rich diet with brown rice improves endothelial function in type 2 diabetes mellitus : A randomized controlled trial . - pubmed
We hypothesized that a fiber - rich diet with brown rice improves endothelial function in patients with type 2 diabetes mellitus . - pubmed
METHODS : Twenty - eight patients with type 2 diabetes mellitus at a single general hospital in Japan were randomly assigned to a brown rice ( n = 14 ) or white rice ( n = 14 ) diet and were followed for 8 weeks . - pubmed
The results of the bacteria ( BAC ) and yeast ( YEA ) analyses were compared with the results from urine culture as a method for UTI screening . - pubmed
The study aimed to establish the fungicidal , efficacy and safety profile of Calmagen dermaceutical cream and lotion containing AMYCOT as a topical treatment in patients with severe to very severe presentations of fungal skin ( tinea ) and nail infections ( onychomycosis ) . - pubmed
METHODS : A randomized , placebo - controlled , double blind , parallel , single centre study was conducted on 28 subjects with severe to very severe tinea or onychomycosis . - pubmed
Uveitis activity improved in 22 eyes of 15 patients ( 13 treated adequately for active TB , 2 not adequately treated ) . - pubmed
All 9 individuals presenting with posterior or panuveitis who improved were adequately treated whereas the remaining 2 who did not improve were not ( P 0.02 ) . - pubmed
Apnea induction for invasive lung function testing in infant olive baboons : Comparison of intravenous propofol versus hyperventilation . - pubmed
We compared two methods of apnea induction in infant olive baboons ( Papio anubis ) . - pubmed
CONCLUSIONS : Intravenous propofol was non - inferior to CO2 washout for apnea induction in infant olive baboons . - pubmed
Perinatal Bisphenol A Exposure Induces Chronic Inflammation in Rabbit Offspring via Modulation of Gut Bacteria and Their Metabolites . - pubmed
In this report , we show how perinatal BPA exposure in rabbits alters gut microbiota and their metabolite profiles , which leads to colonic and liver inflammation as well as to increased gut permeability as measured by elevated serum lipopolysaccharide ( LPS ) levels in the offspring . - pubmed
Also , perinatal BPA exposure leads to reduced levels of gut bacterial diversity and bacterial metabolites ( short - chain fatty acids [ SCFA ] ) and elevated gut permeability - three common early biomarkers of inflammation - promoted chronic diseases . - pubmed
MATERIALS AND METHODS : Twenty - nine patients with amyotrophic lateral sclerosis and 22 healthy controls were scanned with 3 T MR imaging . - pubmed
A statistical analysis assessed the difference in cross - sectional areas between patients with amyotrophic lateral sclerosis and controls , correlations between spinal cord and gray matter atrophy to clinical disability at baseline and at 1 year , and prediction of clinical disability at 1 year . - pubmed
RESULTS : Gray matter atrophy was more sensitive to discriminate patients with amyotrophic lateral sclerosis from controls ( P = .004 ) compared with spinal cord atrophy ( P = .02 ) . - pubmed
We describe the use of a cognitive trainings app by a young woman with highly resistant hallucinations . - pubmed
Phenotypic and genotypic characterization of antimicrobial resistance profiles in Streptococcus dysgalactiae isolated from bovine clinical mastitis in 5 provinces of China . - pubmed
Bovine mastitis is among the most prevalent and costly diseases of dairy animals and is caused by a variety of bacterial pathogens including Streptococcus dysgalactiae . - pubmed
In total , 1,180 milk samples were collected from dairy cows with clinical mastitis belonging to 74 commercial dairy herds located in 14 provinces of China from January 2014 to May 2016 . - pubmed
Setting : HIV / AIDS Cancer Match Study to project cancer rates and HIV Optimization and Prevention Economics model to project HIV prevalence . - pubmed
Chronic iron overload induces vascular dysfunction in resistance pulmonary arteries associated with right ventricular remodeling in rats . - pubmed
Moreover , rats treated with the highest dose exhibited RV dysfunction and hypertrophy ; inward remodeling and increased vasoconstriction of the RPA . - pubmed
The olive knot disease ( Olea europea L. ) is caused by the bacterium Pseudomonas savastanoi pv . - pubmed
Decreased cerebral blood flow and improved cognitive function in patients with end - stage renal disease after peritoneal dialysis : An arterial spin - labelling study . - pubmed
METHODS : ESRD patients undergoing PD were recruited . - pubmed
Age- and sex - matched normal subjects without ESRD served as the control group . - pubmed
RESULTS : ESRD patients showed poor performance in many of the neuropsychological tests ; PD improved cognition in some domains . - pubmed
CONCLUSION : Before PD , ESRD patients had increased cerebral perfusion that was related to poorer executive function , especially in the left hippocampus . - pubmed
KEY POINTS : In this study , ESRD patients before PD had cerebral hyperperfusion that was related to poorer executive function . - pubmed
The degree of anaemia might predict cognitive impairment in PD patients . - pubmed
Seizures , status epilepticus , and seizure - like rhythmic or periodic activities are common , pathological , harmful states of brain electrical activity seen in the electroencephalogram ( EEG ) of patients during critical medical illnesses or acute brain injury . - pubmed
177Lu - DOTA - HYNIC - Lys ( Nal )- Urea - Glu : Biokinetics , Dosimetry , and Evaluation in Patients with Advanced Prostate Cancer . - pubmed
177Lu - iPSMA obtained from kit formulations showed high tumor uptake with good response rates in patients . - pubmed
[ A screening algorithm for patients with adrenal incidentalomas ] . - pubmed
Integrated clinical and economic analysis of the efficiency of screening was made in patients with adrenal incidentalomas under the established practical conditions ; the average cost of screening of a patient with adrenal incidentalomas and the cost of one detected case were determined under these conditions . - pubmed
Based on the clinical and economic analysis , the authors have elaborated and scientifically substantiated an algorithm for screening of patients with adrenal incidentalomas , the use of which will permit , with high clinical efficacy , a significant reduction in the cost of screening . - pubmed
This work measured the hazardous nature of 100 nm micropolystyrene ( MPS ) using 25 , 50 , 100 , 200 , and 400 mg / L concentrations in terms of oxidative stress , morphotoxicity and cytogenotoxicity in Allium cepa . - pubmed
The current study examined whether the precision medicine approach was able to identify specific individuals with BPSD who could benefit from benzoate treatment . - pubmed
Methods : In the randomized , double - blind , placebo - controlled , 6 - week trial , 97 patients with BPSD were allocated to receive 250 - 1500 mg / day of sodium benzoate or placebo . - pubmed
Conclusion : The finding suggests that sodium benzoate may have potential to benefit cognitive function in a fraction of BPSD patients after 6 weeks of treatment . - pubmed
The proposed approach was validated on data obtained from 12 patients with AS . - pubmed
Effect of cryotherapy on arteriovenous fistula puncture - related pain in hemodialysis patients : A systematic review and meta - analysis . - pubmed
BACKGROUND AND PURPOSE : Patients undergoing continuous hemodialysis experience the arteriovenous fistula puncture - related pain approximately 300 times per year . - pubmed
Therefore , this systematic review and meta - analysis study was conducted to determine the effect of cryotherapy on arteriovenous fistula puncture - related pain in hemodialysis patients . - pubmed
The review of studies showed a positive effect of cryotherapy on reducing the arteriovenous fistula puncture - related pain in hemodialysis patients . - pubmed
Retinoblastoma ( RB ) is one of the most common primary intraocular malignancies in children . - pubmed
Consistently , the higher expression levels of miR-424 were closely associated with the poor clinical outcome of the bladder cancer patients . - pubmed
To summarize the distribution of glioma location within a patient population , registration of individual MR images to anatomical reference space is required . - pubmed
Objective : To compare the clinical and imaging characteristics of patients with stage I coal worker 's pneumoconiosis ( CWP ) . - pubmed
We performed a systematic review and meta - analysis to evaluate the efficacy of probiotics in improving gastrointestinal ( GI ) symptoms and quality of life ( QOL ) in patients with CD . - pubmed
DISCUSSION : Probiotics may improve GI symptoms in patients with CD . - pubmed
To assess the accuracy of the mammary volume - to - body mass index ( MV - BMI ) ratio as an indicator of cardiovascular disease ( CVD ) risk in morbidly obese patients and as a preoperative predictor of long - term outcomes after SG . - pubmed
RESULTS : Thirty - two patients with CNLDO were included . - pubmed
Gram - positive bacteria accounted for 60.5 % of all the strains , with Streptococcus ( 50 % ) being the most frequent species , whereas Haemophilus ( 21.1 % ) and Neisseriae ( 13.2 % ) were most common isolates for Gram - negative organisms . - pubmed
CONCLUSIONS : Infants with CNLDO under 1 year of age presented predominance of Streptococcus as Gram - positive organism , and Haemophilus as Gram - negative organism . - pubmed
PET imaging assessed the localization of 89Zr - REGN3504 to multiple human tumor xenografts . - pubmed
RESULTS : Clear localization of 89Zr - REGN3504 to human tumor xenografts was observed via PET imaging and ex vivo biodistribution studies demonstrated high ( fourfold to sixfold ) tumor : blood ratios . - pubmed
Serial bleedings were obtained from two mules during prolonged immunization , one with type XXV the other with type VIII pneumococcal vaccine . - pubmed
Thus , until a superior regimen is established , I recommend local and regional irradiation for patients at high risk for recurrence . - pubmed
Thirty - nine patients with small cell lung cancer were treated with large dose intravenous cyclophosphamide combined with vincristine . - pubmed
Perinatal hypothyroidism in rats : persistent motivational and metabolic effects . - pubmed
These rats also showed hyperactivity in asymptotic running - wheel performance , increased spontaneous recovery of extinguished lever - pressing , and elevated responding in lever - pressing for variable - interval food reinforcement . - pubmed
In general the results indicate that perinatal thyroid deficiency engenders a chronic hypermetabolic state in both sexes which may be associated with a persistent , mild hyperthyroid condition in the case of female rats . - pubmed
The p locus is closely linked to the mouse homolog of a gene from the Prader - Willi chromosomal region . - pubmed
Renal hypertrophy and hyperfiltration are early manifestations of human and experimental diabetes that may contribute to the late development of diabetic nephropathy . - pubmed
Since growth of various tissues is accompanied by increased formation of polyamines , we studied whether polyamines were involved in the growth of the kidney observed in diabetic rats . - pubmed
[ The influence of soft tissue contractures on the walking ability of patients with spastic cerebral palsy ] . - pubmed
The influence of soft tissue contractures on walking ability was investigated in 73 patients with spastic cerebral palsy . - pubmed
Currently , there is confusion in the literature regarding appropriate treatment of patients known to possess these antibodies . - pubmed
We have reported the case of a patient at 29 weeks ' gestation who had elevated blood pressure , proteinuria , and early intrauterine growth retardation . - pubmed
After delivery , chest pain and a pleural effusion developed as further manifestations of the patient 's autoimmune disease . - pubmed
An 65 - year - old woman sustained respiratory distress after coronary artery bypass grafting because of bilateral phrenic nerve paralysis . - pubmed
We believe that surgical plication of the diaphragm is a safe and effective technique for a distressed adult patient with paralyzed diaphragm . - pubmed
Double - blind placebo - controlled study of nortriptyline in depressed adolescents using a " fixed plasma level " design . - pubmed
All three men with the deficiency had severe , chronic , bilateral , lower extremity , venous insufficiency manifested by pain , varicosities , edema , pigmentation , and ulceration . - pubmed
The calves were assigned to four treatment groups balanced according to body weight . - pubmed
Calves fed the low P ( deficient ) diet showed significant reductions in feed intake , weight gain , serum inorganic P , bone ash , and P content of bone . - pubmed
Twenty - nine patients with stage III testicular tumours seen between 1979 and 1984 were analysed for the relation between delay in both diagnosis and chemotherapy , and prognosis . - pubmed
Biochemical characteristics of mouse mammary tissues , preneoplastic lesions and tumors . - pubmed
A number of metabolizing systems are measured in normal , preneoplastic and neoplastic mouse mammary tissues derived under three different conditions . - pubmed
Role of thiol agents in protecting against the toxicity of helenalin in tumor - bearing mice . - pubmed
Helanalin , a sesquiterpene lactone antineoplastic agent , is toxic at therapeutic doses in murine tumors . - pubmed
with L - cysteine ( 100 mg / kg / day ) , beta - mercaptoethanolamine ( 20 mg / kg / day ) , 18 - beta - glycyrrhetinic acid ( 15 mg / kg / day ) , or 4,4 '- diaminodiphenylsulfone ( 10 mg / kg / day ) afforded improvement in survival of mice bearing P-388 lymphocytic leukemia . - pubmed
Antibody titers were significantly higher in patients with an intraventricular vesicle or cyst . - pubmed
A 10 year - old girl presented with a progressive left ureteral colic with abdominal tenderness . - pubmed
Serum antibody does not account for differences in the severity of chronic respiratory disease caused by Mycoplasma pulmonis in LEW and F344 rats . - pubmed
Chronic respiratory disease in rats , resulting from Mycoplasma pulmonis infection , is useful in the study of the immunological mechanisms in similar inflammatory diseases and provides a unique opportunity to study the interactions between systemic and mucosal immune systems in a naturally occurring infection . - pubmed
pulmonis in strains of rats which differ in disease progression and severity ; LEW rats developed more severe disease than did F344 rats . - pubmed
pulmonis antigens than did F344 rats , and there was no difference in the antigens eventually recognized by each strain , confirming previous work which suggested that LEW rats do not exhibit an unresponsiveness to a specific antigen(s ) of M. - pubmed
Computerized tomography was positive for pituitary tumour in three patients . - pubmed
Reproducibility of ventilatory measurements during sleep on different nights in patients with chronic obstructive pulmonary disease . - pubmed
To evaluate the reproducibility of respiratory measurements between nights we performed studies in 20 outpatients with stable , moderately severe chronic obstructive pulmonary disease . - pubmed
All patients had symptoms from their lung disease but had no sleep complaints . - pubmed
Urinary tract infections in patients undergoing transurethral prostatectomy . - pubmed
The incidence of urinary tract infections was determined in 1,660 patients undergoing transurethral prostatectomy . - pubmed
Preoperative infection was found in 25 % of all patients and in 35 % of the 276 patients aged 80 years or over . - pubmed
Of the 1,251 patients without a preoperative infection , 17 % had postoperative infections . - pubmed
This report describes a patient with severe subaortic stenosis , patent ductus arteriosus , and mild pulmonary branch stenosis , a rare condition . - pubmed
A 6 3/4 - year - old boy with neuronopathic Gaucher ' s disease died unexpectedly . - pubmed
After 575 renal transplantations with 147 angiographies arterial stenoses were observed in nine patients ( 1,6 % ) and corrected surgically . - pubmed
Attempts to close a median sternotomy incision in the patient with profound cardiac or pulmonary dysfunction following a cardiac surgical procedure can result in severe hemodynamic deterioration . - pubmed
[ Preliminary studies of porcine piroplasmosis in the northern Ivory Coast . - pubmed
Antibody studies of sera from patients with breast cancer . - pubmed
Metabolic and heart rate response of the plethodontid salamander Desmognathus fuscus to hypoxia . - pubmed
Relapse mechanisms in malaria : emergence of variant strains of Plasmodium lophurae from serum antigen - immunized ducks . - pubmed
Patient is now alive 3 years posttherapy with a functional vagina , return of menses , and without evidence of tumor . - pubmed
[ Structuro - functional transformation of the microcirculatory bed of the lungs in children with chronic nonspecific inflammation of the lungs ] . - pubmed
Considerable morphological alterations in the capillary network found in patients with a coarse deforming bronchitis confirmed the reasons for the surgical treatment of such patients . - pubmed
Differentiation of human myeloid leukemic cells by phorbol esters : correlation with tumor promotion . - pubmed
Similar results were obtained in 3 different established cell lines , as well as in short - term cultures of cells obtained from patients with acute myeloid leukemia . - pubmed
Clinical and urodynamic examinations were carried out in 63 patients with Parkinson ' s disease presenting with disorders of the urinary bladder sphincters with no detectable other neurological or urological cause . - pubmed
[ Interrelation of the functional activity of leukocytes in the bronchial secretion and peripheral blood of patients with nonspecific lung diseases ] . - pubmed
[ Development of lymphoma and leukemia in patients receiving immunosuppressive drugs ] . - pubmed
Seventy - five strains of Clostridium difficile were recovered from 1,276 stools from patients . - pubmed
For this reason , we tested serum samples from patients with typhoid fever , brucellosis , toxoplasmosis , amoebiasis , cysticercosis , trichocephaliasis , ascariasis , and onchocerciasis against an antigenic extract of T. - pubmed
A patient with Terrien ' s corneal marginal degeneration and a previous trabeculectomy had planned extracapsular cataract extraction with intraocular lens implantation . - pubmed
Bone turnover in asthmatic children treated with oral prednisolone or inhaled budesonide . - pubmed
Biochemical markers of bone turnover were studied in prepubertal school children with asthma in two randomized double - blind crossover trials with run - in , treatment , and wash - out periods of 2 weeks . - pubmed
Short - term treatment with low daily doses of prednisolone may cause a suppression of bone turnover in children with asthma . - pubmed
Choreoathetosis developed in three patients after cardiopulmonary bypass with hypothermia . - pubmed
The infusion of anti - RhO-(D ) opsonized erythrocytes may be useful in the treatment of patients , splenectomized or not , with chronic , refractory autoimmune thrombocytopenic purpura -- a prospective study . - pubmed
Ten patients with extensive plaque psoriasis were treated with calcipotriol ointment ( 50 micrograms / g ) for 2 weeks ( 200 g for 1 week , followed by 300 g during the second week ) . - pubmed
Topical calcipotriol is an effective , rapidly acting and safe in - patient treatment for extensive plaque psoriasis . - pubmed
We report postmortem findings in a 46 - year - old man with dominantly inherited parkinsonism whose symptoms started at age 28 . - pubmed
Dystonia is a prominent feature in several of the youngest patients , but was not present in this patient . - pubmed
The case of a 51 year old woman diagnosed with hereditary angioneurotic edema ( HANE ) requiring hospital admission on one occasion is presented . - pubmed
Scedosporium apiospermum pneumonia after autologous bone marrow transplantation . - pubmed
When the patient failed to improve , Scedosporium apiospermum pneumonia was diagnosed and therapy was changed . - pubmed
Ultrastructural changes in immature articular cartilage were studied after treatment of 5 - wk - old rats with ofloxacin - a fluoroquinolone - and in magnesium deficiency . - pubmed
Magnesium deficiency was induced by feeding a magnesium - deficient diet for 9 days ; the condition was confirmed by measuring the concentrations of the mineral in plasma , bone , and cartilage samples of the animals by atomic absorption spectrophotometry . - pubmed
Alterations observed on the ultrastructural level showed striking similarities in magnesium - deficient rats and in rats treated with single doses of 600 mg ofloxacin / kg body weight . - pubmed
Adenomas were obtained from 10 patients with Cushing ' s disease . - pubmed
METHODS : The highly vascularized chicken comb was selected as the animal model for hemangiomas . - pubmed
We studied two groups : 1 ) 82 young healthy normal controls and 2 ) 48 patients with noninsulin dependent diabetes mellitus ( NIDDM ) and 24 appropriately matched controls . - pubmed
Effect of low dose methotrexate on markers of bone metabolism in patients with rheumatoid arthritis . - pubmed
OBJECTIVE : To evaluate markers of bone metabolism in patients with active rheumatoid arthritis ( RA ) and the effect of weekly low dose methotrexate ( MTX ) on bone turnover . - pubmed
METHODS : Forty - two menstruating female patients recently diagnosed to have RA ( mean age 35.4 years , mean disease duration 1.03 years ) were enrolled in this study . - pubmed
CONCLUSION : In patients with RA bone metabolism is affected . - pubmed
The therapy of weekly low dose MTX had improved bone resorption , suggesting that in patients with RA MTX might have a bone protective effect by controlling disease activity . - pubmed
Degenerate disc samples were collected from low back pain patients undergoing anterior interbody fusion due to severe , discographically verified and painful disc degeneration , and from the posterior parts of intervertebral discs from 10 patients undergoing microscopic discoidectomy because of intervertebral herniation . - pubmed
Pooled colonies of hygromycin - resistant cells were then tested in C3H / He mice for their immunotherapeutic properties against the growth of the breast neoplasm . - pubmed
The results indicated that tumor - bearing mice immunized with the transfected cells survived significantly longer than mice in various control groups . - pubmed
Similar beneficial effects were seen in C57BL / 6 mice injected with a syngeneic breast carcinoma cell line ( EO771 ) and semiallogeneic , IL-2 - secreting fibroblasts transfected with DNA from EO771 cells . - pubmed
[ How should taxonomic confusions of Caliciviridae , particularly of caliciviruses causing gastroenteritis in humans , be resolved ? - pubmed
We report a 17 - year - old boy with severe pyoderma gangrenosum treated successfully with mycophenolate mofetil and autologous keratinocyte transplantation using an esterified hyluronic acid delivery system . - pubmed
METHODS : The study involved 196 patients with Type 1 diabetes mellitus ( age range 2 - 24 years , onset of diabetes before the age of 12 years , duration of disease longer than 2 years ) , without clinical and laboratory signs of microvascular complications ; they were divided into three groups ( group 1 - n = 37 , age & lt ; 6 years ; group 2 - n = 71 , age 6 - 12 years ; group 3 - n = 88 , age & gt ; 12 years ) . - pubmed
A total of 223 healthy controls were matched for age and sex with each group of patients with diabetes mellitus . - pubmed
Efficacy and safety of clozapine and olanzapine : an open - label study comparing two groups of Parkinson ' s disease patients with dopaminergic - induced psychosis . - pubmed
Clozapine , an atypical neuroleptic agent , improves dopaminergic - induced psychosis in parkinsonian patients without increasing motor disability . - pubmed
Therefore , for 12weeks we compared the tolerability and efficacy of clozapine and olanzapine in two groups of nine consecutive parkinsonian psychotic patients treated with these compounds . - pubmed
All the patients on clozapine ( mean starting dose : 13.1+/-7.9mg / d ) completed the study despite reporting a number of adverse events , including somnolence , falls , orthostatic hypotension , and syncope . - pubmed
In contrast , early withdrawal occurred in three of the nine patients receiving olanzapine , due to severe gait deterioration and drowsiness ( mean starting dose : 3.9+/-1.3mg / d ) . - pubmed
Conversely , the six patients receiving olanzapine who finished the study experienced aggravated parkinsonian symptoms , with a 25.5 % worsening in the raw scores and a 24.6 % worsening in the weighted scores ( mean dose : 4.7+/-2.3mg / d ) . - pubmed
We report a patient who developed nitroimidazole - induced chronic hepatitis following acute exacerbation of hepatitis three times after nitroimidazole use . - pubmed
OBJECTIVE : We sought to evaluate the efficacy of an increased venom dose in patients allergic to Hymenoptera venom still reacting systemically to a sting challenge despite immunotherapy with 100 microg of venom every 4 weeks . - pubmed
RESULTS : While receiving a maintenance dose of 100 microg of venom every 4 weeks for 7 to 38 months , 18 patients reacted systemically to a bee sting and 22 reacted to a wasp sting . - pubmed
After an increase of the maintenance dose to 150 microg , 2 of 4 patients allergic to bee venom ( BV ) and 6 of 6 patients allergic to yellow jacket venom ( YJV ) no longer reacted systemically to the sting challenge . - pubmed
Of those 4 individuals not protected by the first dose increase , one patient allergic to BV ( prior dose of 150 microg ) and one patient allergic to YJV ( prior dose of 200 microg ) did not react systemically to a further sting challenge while receiving 200 microg of BV or 250 microg of YJV , respectively . - pubmed
One patient allergic to BV who had a systemic reaction to the sting challenge while receiving 150 microg was not protected after a dose increase to 200 microg ; she later received a dose of 400 microg of BV , and no further sting challenge was performed . - pubmed
The patient allergic to BV who still reacted systemically after a first dose increase to 200 microg was a female patient with urticaria pigmentosa . - pubmed
[ The six minute walking test elicits lung hyperinflation in patients with severe chronic obstructive lung disease ] . - pubmed
BACKGROUND : Exercise tolerance in patients with COPD is highly variable and poorly related to airways obstruction assessed by FEV1 . - pubmed
These patients develop dynamic hyperinflation ( DH ) during an incremental exercise test which can be evaluated through a reduction in inspiratory capacity ( IC ) . - pubmed
SUBJECTS AND METHODS : Thirty eight stable COPD patients ( 28 FL and ten non FL during resting breathing , determined by the negative pressure technique ) . - pubmed
Although no differences were found between groups in 6 MWD , dyspnea and HR , a significant reduction in IC after the walking test was observed only in FL patients ( p & lt ; 0.0001 ) . - pubmed
CONCLUSIONS : Our results demonstrate that a moderate exercise such as the walking test induces DH and hypoxemia in patients with COPD and FL and stresses the importance of assessing DH by measuring IC in these patients . - pubmed
Panic disorder patients have reduced cyclic AMP in platelets . - pubmed
Abnormalities in the cyclic AMP system have been described in several psychiatric disorders but there are no studies in panic patients . - pubmed
Average baseline cyclic AMP of PD patients was lower than after remission of panic attacks ( P<0.005 ) and lower than in healthy volunteers ( P<0.005 ) . - pubmed
Average cyclic AMP after remission of panic attacks was not significantly different than in healthy volunteers . - pubmed
Our results suggest that PD patients without treatment have lower platelets cyclic AMP levels than healthy volunteers and that this decrease may be corrected by clomipramine . - pubmed
RESULTS : A human RCC subtractive library with high subtractive efficiency was successfully set up . - pubmed
CONCLUSIONS : The constructed cDNA subtractive library of human RCC is a highly efficient one and lays a solid foundation for large scale screening and cloning new and specific oncogenes or tumor suppressor genes of RCC . - pubmed
Development of resistance to cytarabine ( AraC ) is a major problem in the treatment of patients with acute myeloid leukemia ( AML ) . - pubmed
We report the case of a 9 - year - old boy presenting with multifocal paraganglioma partially involving the right suprarenal gland , abdominal paraganglia , and the left para - aortal retropleural region . - pubmed
Patients with VHL disease should undergo adrenal - sparing surgery . - pubmed
Multicentric inflammation in epicardial coronary arteries of patients dying of acute myocardial infarction . - pubmed
OBJECTIVES : We sought to test the hypothesis of whether inflammatory cell infiltration in patients dying of an acute myocardial infarction ( MI ) is a multifocal event involving multiple coronary branches . - pubmed
METHODS : We performed a systematic flow cytometric study in three groups of autopsied patients ( group 1 = acute MI ; group 2 = old MI ; group 3 = no ischemic heart disease ) . - pubmed
A total of 125 patients with locoregional or disseminated malignant melanoma were randomized to receive dacarbazine ( 250 mg / m(2 ) days 1 - 5 every 3 weeks ) plus tamoxifen ( arm A ) or vindesine ( 3 mg / m(2 ) every week for 6 weeks , then every 2 weeks ) plus tamoxifen ( arm B ) . - pubmed
The long - lasting efficacy and effectiveness of DTPa vaccines have been extensively documented and these are now the cornerstone of a large range of combined vaccines including DTPa - hepatitis B ( HBV ) , DTPa - inactivated polio ( IPV ) and DTPa - HBV - IPV . - pubmed
Four humeral defects per dog were implanted with one of each of the putty formulations while the fourth defect was left untreated . - pubmed
Comparison of dye - dilution and flowmeter estimates of pulmonary valve incompetence in dogs . - pubmed
MATERIALS AND METHODS : Twenty - five children with intractable OME were studied . - pubmed
Thirteen patients were confirmed allergy positive by multiallergosorbent test . - pubmed
Twelve patients were allergy negative . - pubmed
The data collected suggest that beauvericin exerts a substantial dose- and time - dependent cytotoxic effect on invertebrate cells , comparable to the effects described in mammalian cells . - pubmed
The clinical response and histological analyses were studied in an adjuvant arthritic rat model . - pubmed
The fusion protein also suppressed joint swelling ( paw circumference reduced from 5.0 + /- 0.2 to 4.1 + /- 0.1 cm ; paw thickness approximately 2 mm in difference ) and synovial inflammation in adjuvant arthritis of rats . - pubmed
Plasmodium vivax causes the majority of malaria outside of sub - Saharan Africa and is an important burden for affected countries . - pubmed
Scabies is a disease of global proportions in both human and animal populations , resulting from infestation of the skin with the " itch " mite Sarcoptes scabiei . - pubmed
We report successful treatment by bone marrow transplantation ( BMT ) in an acute myeloid leukemia ( AML ) patient with Glanzmann thrombasthenia ( GT ) . - pubmed
Induction therapy for AML was performed with frequent platelet transfusions because of the patient 's severe hemorrhagic manifestations . - pubmed
Videoreflective dacryomeniscometry in normal adults and in patients with functional or primary acquired nasolacrimal duct obstruction . - pubmed
PURPOSE : Videoreflective dacryomeniscometry ( VRD ) for evaluation of marginal tear film has not been performed in patients with watery eye or in a controlled study . - pubmed
METHODS : We evaluated with VRD 20 subjects with normal lacrimal drainage function , 21 patients with primary acquired nasolacrimal duct obstruction ( PANDO ) , 28 patients with functional nasolacrimal duct obstruction ( FNLDO ) , and a postoperative group of 14 patients derived from the previous two pathologic groups . - pubmed
In the second trial ( weight loss ) , 29 subjects were similarly randomized to the low or high dairy diets and placed on a caloric restriction regimen ( -500 kcal / d ) . - pubmed
We present the case of a patient with a second delivery who arrived at the Gynecology Service due to referring intense pain in the episiorrhaphy scar as well as superficial dyspareunia . - pubmed
Prevalence , behavioural and social factors associated with Schistosoma intercalatum and geohelminth infections in Sao Tome and Principe . - pubmed
A pilot study was conducted in schoolchildren from three main districts of Sao Tome to assess the relationship between the prevalence of infections caused by Schistosoma intercalatum or intestinal helminths and individual behaviour and social conditions . - pubmed
Infection rates were 36.2 % for S. - pubmed
BACKGROUND : The majority of patients with thyrotoxicosis are readily diagnosed clinically . - pubmed
CASE REPORT : A 45 - year - old woman presented with choreoathetoid movements of the right upper limb , persistent vomiting and generalized body weakness . - pubmed
Although mechanical ventilation ( MV ) is an important supportive strategy for patients with acute respiratory distress syndrome , MV itself can cause a type of acute lung damage termed ventilator - induced lung injury ( VILI ) . - pubmed
These medications have been used primarily in women with breast carcinoma and also in children with autonomous estrogen production , such as patients with McCune - Albright Syndrome . - pubmed
placebo ( bid , n=28 ) in previously diet - treated subjects with type 2 diabetes . - pubmed
CONCLUSION : monotherapy with vildagliptin is well tolerated and improves glycemic control in diet - treated subjects with type 2 diabetes . - pubmed
Poorer outcome of elderly patients treated with extended - field radiotherapy compared with involved - field radiotherapy after chemotherapy for Hodgkin ' s lymphoma : an analysis from the German Hodgkin Study Group . - pubmed
BACKGROUND : The optimal treatment of elderly patients with Hodgkin ' s lymphoma ( HL ) is still a matter of debate . - pubmed
CONCLUSION : Elderly patients with early - stage unfavorable HL generally have a poorer risk profile and outcome when compared with younger patients . - pubmed
OBJECTIVE : To evaluate the safety and efficacy of orally administered ruboxistaurin ( RBX ) as a mesylate salt in patients with diabetic macular edema ( DME ) . - pubmed
At baseline , patients had DME farther than 300 mum from the center of the macula , an Early Treatment Diabetic Retinopathy Study retinopathy severity level from 20 to 47A without prior photocoagulation , and an Early Treatment Diabetic Retinopathy Study visual acuity of 75 or more letters in the study eye . - pubmed
We report a case of invasive lymphangioma of the lung , diagnosed in a 9 - year - old girl who presented with intractable hemoptysis and a large pulmonary mass , 10 cm in diameter . - pubmed
The authors reviewed 79 ( 37 boys , 42 girls ) cases of empyema thoracis who underwent thoracotomy and decortication between 1990 and 2005 . - pubmed
METHODS : Sixty - eight patients were admitted into our hospital for acute pancreatitis and treated in our ICU for computed tomography - proven severe acute pancreatitis during the years 1997 to 2004 . - pubmed
Anesthetized rabbits were subjected to 60 min of left coronary artery occlusion and 180 min of reperfusion with ( I / R - VS , n = 8) or without vagal nerve stimulation ( I / R , n = 7 ) . - pubmed
Rabbits not subjected to coronary occlusion with ( VS , n = 7 ) or without vagal stimulation ( sham , n = 7 ) were used as controls . - pubmed
One - week acid suppression trial in uninvestigated dyspepsia patients with epigastric pain or burning to predict response to 8 weeks ' treatment with esomeprazole : a randomized , placebo - controlled study . - pubmed
BACKGROUND : While empiric acid - suppressive therapy for uninvestigated dyspepsia patients with symptoms of epigastric pain or burning is standard practice , it is unknown whether an early response to therapy predicts outcome . - pubmed
METHODS : Helicobacter pylori - negative patients ( aged 18 - 50 years ) in primary care with uninvestigated epigastric pain or burning were randomized to esomeprazole 40 mg q.d.s . - pubmed
CONCLUSION : A 1 - w acid suppression trial is of limited clinical value for predicting 8 - w response in patients with symptoms of epigastric pain or burning . - pubmed
PURPOSE : To report the results of patients with early - stage anal cancer treated using a low - dose , reduced - volume , involved - field chemoradiotherapy protocol . - pubmed
RESULTS : After a median follow - up of 42 months , only 1 patient ( 4.7 % ) had experienced local recurrence and has remained disease free after local excision . - pubmed
Only 1 patient could not complete treatment ( because of Grade 3 gastrointestinal toxicity ) . - pubmed
Grade 3 - 4 hematologic toxicity occurred in only 2 patients ( 9.5 % ) . - pubmed
CONCLUSION : The results of our study have shown that for patients with anal carcinoma who have residual microscopic or very - small - volume disease , a policy of low - dose , reduced - volume , involved - field chemoradiotherapy produces excellent local control and disease - free survival , with low rates of acute and late toxicity . - pubmed
The effectiveness of acupuncture on pain and mobility in patients with osteoarthritis of the knee : a pilot study . - pubmed
In this pilot clinical study , acupuncture was incorporated into the standard care for adult patients with osteoarthritis of the knee to determine its contribution to pain relief and improved mobility . - pubmed
In a prospective , non - randomized controlled study , patients with osteoarthritis of the knee were separated into two groups . - pubmed
Patients with osteoarthritis of the knee seemed to experience clinical improvements in six - minute walking distance , pain relief and mobility when their standard care was supplemented with acupuncture . - pubmed
BACKGROUND : In the description of 1 episode schizophrenia patients , female gender is associated with better social function and a higher degree of compliance , while males exhibit more negative symptoms and a higher degree of abuse . - pubmed
In addition , in vivo studies demonstrated that oral administration of these two compounds at 20 - 100 mg / kg resulted in similar inhibitory activities against several animal models of inflammation / allergy : arachidonic acid - induced mouse ear edema , carrageenan - induced mouse paw edema and passive cutaneous anaphylaxis . - pubmed
BACKGROUND : There is no consensus on the long - term outcome after unifocalization in patients undergoing surgery for pulmonary atresia with ventricular septal defects ( VSD ) and major aortopulmonary collateral arteries ( MAPCAs ) . - pubmed
METHODS AND RESULTS : From 1988 to 2006 , 40 patients ( median age 8.5 months ) underwent surgery for pulmonary atresia , VSD , and MAPCAs . - pubmed
RESULTS : One hundred and seventy - five AA patients were included in this analysis . - pubmed
CONCLUSION : The use and type of induction therapy in AA patients significantly reduces acute rejection rates and may improve long - term graft outcomes in AA patients . - pubmed
Biometric and corneal topographic characteristics in patients with Weill - Marchesani syndrome . - pubmed
PURPOSE : To determine the biometry of ocular structures and corneal topographic characteristics in patients with Weill - Marchesani syndrome . - pubmed
METHODS : Patients with Weill - Marchesani syndrome ( syndrome group ) and age - matched normal subjects ( control group ) were evaluated . - pubmed
RESULTS : The syndrome group comprised 7 female patients and the control group , 20 female subjects . - pubmed
CONCLUSION : Characteristic ocular findings in patients with Weill - Marchesani syndrome were a steep , thick cornea with a strong right - left specificity of corneal astigmatism ; a thick lens ; a short AL ; and a shallow ACD . - pubmed
We recorded the local field potentials ( LFPs ) via implanted electrodes in the rostrolateral part of the periventricular and periaqueductal gray in four patients ( six electrodes ) who underwent deep brain stimulation for treatment of neuropathic pain . - pubmed
One hundred twenty three patients with chronic hepatitis C were enrolled in the study . - pubmed
Infection with CMV was diagnosed through the detection of CMV DNA in sera by means of RT - PCR method . - pubmed
The early virologic response to anti - HCV therapy was independent of CMV infection . - pubmed
Clustering of admission hyperglycemia , impaired renal function and anemia and its impact on in - hospital outcomes in patients with ST - elevation myocardial infarction . - pubmed
OBJECTIVE : To examine the incidence and inter - relationships between admission hyperglycemia , anemia and impaired renal function and its impact on clinical outcomes in patients with ST - elevation myocardial infarction ( STEMI ) treated with primary PCI . - pubmed
METHODS : The study group comprised 1880 patients with STEMI treated with primary PCI , enrolled in a prospective registry . - pubmed
RESULTS : The primary endpoint of in - hospital death occurred in 88 ( 4.7 % ) patients . - pubmed
Hyperglycemia ( glucose & gt;11.1mmol / L ) was present in 352(18.7 % ) , anemia ( hematocrit & lt;36 % women , & lt;39 % men ) in 396(21.1 % ) , and increased serum creatinine ( & gt ; or = 1.2mg / dL women , & gt ; or = 1.3mg / dL men ) in 423(22.5 % ) patients . - pubmed
Of late , however , two recently developed interventions -- constraint - induced movement therapy ( CIMT ) and bilateral arm training with rhythmic auditory cueing ( BATRAC)--have shown promising results in the treatment of upper limb paresis in chronic stroke patients . - pubmed
The ULTRA - stroke ( acronym for Upper Limb TRaining After stroke ) program was conceived to assess the effectiveness of these interventions in subacute stroke patients and to examine how the observed changes in sensori - motor functioning relate to changes in stroke recovery mechanisms associated with peripheral stiffness , interlimb interactions , and cortical inter- and intrahemispheric networks . - pubmed
METHODS / DESIGN : Sixty patients with a first ever stroke will be recruited . - pubmed
The supposed origin of swine - influenza in the U.S.A. in 1918 and the presence of antibodies to swine - influenza in the sera of most adult human beings have led to a suggestion that swine - influenza is a survival in the pig of 1918-'flu . - pubmed
Factors concerned in the immunity of experimental animals to influenza are discussed- degrees of immunity in the ferret ; immunity of the nasal passages to big doses of virus ; immunity of the lungs ; immunity to contact infection . - pubmed
In planning vaccination of human beings we wonder:-(1 ) Whether , on general epidemiological grounds , an attempt to vaccinate against influenza virus is likely to be profitable. - pubmed
PATIENTS AND METHODS : Two patients with extended osteonecrosis of the lower jaw ( osteoradionecrosis or bisphosphonate - related osteonecrosis of the jaw ) were treated with partial mandibulectomy . - pubmed
In this symposium , an international group of multidisciplinary experts discusses the role of tight glycemic control , glucose measurement technique and its accuracy , glucose variability , hypoglycemia , and innovative methods to facilitate glucose homeostasis in this heterogeneous patient population . - pubmed
MATERIALS AND METHODS : We describe the clinical , histological and radiological features of an unusual magnetic resonance imaging ( MRI ) and deep intramuscular location of GCT - ST with fluid - fluid levels ( FFLs ) simulating other soft tissue tumors or a hydatid cyst in a 52 - year - old man . - pubmed
Pathological examination of excised skin in patients with hidradenitis foci is recommended , especially in the case of extra - axillary lesions . - pubmed
The patients were classified into 2 groups : A = CIDO with DS and B = CIDO with non - DS ( NDS ) . - pubmed
RESULTS : A total of 227 patients ( male - female = 108:119 ) underwent surgical correction of CIDO . - pubmed
Of 227 patients , 86 ( 37.9 % ) were shown to have DS ( group A ) , and 141 ( 62.1 % ) were NDS patients ( group B ) . - pubmed
It is concluded that DS negatively impacts the management and outcome of patients with CIDO . - pubmed
Potassium deficiency induces the biosynthesis of oxylipins and glucosinolates in Arabidopsis thaliana . - pubmed
METHODS : Between July 2003 and November 2008 , 30 relapsed SCLC patients receiving 35 mg / m(2)/day of AMR were evaluated . - pubmed
Febrile neutropenia occurred in three patients ( 10 % ) . - pubmed
We developed a pig kidney allograft model of DGF and evaluated the cytoprotective effects of inhaled carbon monoxide ( CO ) . - pubmed
In vitro in pig renal epithelial cells , CO blocks anoxia - reoxygenation - induced cell death while promoting proliferation . - pubmed
This large animal model of DGF can be utilized for testing therapeutic strategies to reduce or prevent DGF in humans . - pubmed
Supratentorial PNET in a young child . - pubmed
These agents include cytomegalovirus ; Epstein - Barr virus ; herpes simplex virus ; varicella - zoster virus ; human herpesvirus 6 , 7 , and 8 ; human parvovirus B19 ; adenoviruses among others . - pubmed
Human herpesviruses 6 , 7 , and 8 , human parvovirus B19 , and adenoviruses can also be present with features of acute liver injury and occasionally as fulminant hepatitis . - pubmed
METHODS : A prospective study of a series of 9 patients with recent retinal vein occlusion with macular edema treated with sustained - release dexamethasone 0.7 mg intravitreal implant was performed . - pubmed
RESULTS : Nine eyes of 9 consecutive patients treated with a total of 9 sustained - release dexamethasone 0.7 mg intravitreal implants for macular edema associated with retinal vein occlusion were included . - pubmed
Five patients had central retinal vein occlusion and 4 patients had branch retinal vein occlusion . - pubmed
Accentuated ischemia was associated in 2/5 patients with central retinal vein occlusion . - pubmed
CONCLUSIONS : In patients with macular edema in retinal vein occlusion , sustained - release dexamethasone 0.7 mg intravitreal implant may be an effective treatment option to control macular edema . - pubmed
We present the case of a patient with an aberrant right subclavian artery with a small calcified aneurysm in a Kommerell ' s diverticulum that caused chest pain and dysphagia ; the patient underwent a procedure combining endovascular and surgical treatment . - pubmed
This relationship between these attentional networks and anxiety may in part explain the problems in the day - to - day functioning of these patients . - pubmed
Should all patients with pulmonary hypertension undergo HIV serologic testing ? - pubmed
OBJECTIVES : To evaluate the yield of screening patients with pulmonary hypertension ( PH ) for human immunodeficiency virus ( HIV ) infection . - pubmed
RESULTS : We identified 445 patients with PH who had serologic testing for HIV antibody . - pubmed
Only 1 patient ( 0.2 % ; 95 % confidence interval , 0.0%-1.2 % ) was positive for HIV , and this was the only patient who had a known history of HIV infection . - pubmed
The patient who tested positive for HIV had PAH , yielding an estimated prevalence of positive HIV testing in that subgroup of 0.4 % ( 95 % confidence interval , 0.0%-2.5 % ) ; 6 other patients with PAH ( 2.7 % ) had risk factors for HIV but negative serology . - pubmed
CONCLUSIONS : To our knowledge , this is the first study examining the yield of screening patients with PH for HIV using serologic testing . - pubmed
Patients with PAH should be assessed for risk factors for HIV before testing for HIV in low - risk populations . - pubmed
MATERIALS AND METHODS : A total of 67 patients , 32 premalignant lesions and other 35 frank oral carcinomas , were included in the study . - pubmed
BACKGROUND : It is well - known that tumor exerts nonmetastatic systemic effect on organism caused the development of paraneoplastic syndrome ( PNS ) . - pubmed
In this review , we discuss the development of the cranial vault and explain the basic science behind craniosynostosis in humans as well as in animal models and how these studies may lead to future advances in craniosynostosis treatments . - pubmed
Moreover , when cervical degenerative diseases are treated with a combination of decompression and posterior instrumented fusion , patients are at increased risk for C-5 palsy . - pubmed
RESULTS : Ten ( 11.9 % ) of 84 patients developed postoperative C-5 palsy . - pubmed
CONCLUSIONS : Patients with preoperative foraminal stenosis , posterior shift of the spinal cord , and additional iatrogenic foraminal stenosis due to cervical alignment correction were more likely to develop postoperative C-5 palsy after posterior instrumentation with fusion . - pubmed
In this study , we tested the ability of Fasciola hepatica total extract ( TE ) to induce tolerogenic properties in CpG - ODN ( CpG ) maturated DC , to then evaluate the therapeutic potential of these cells to diminish the inflammatory response in collagen induced arthritis ( CIA ) . - pubmed
BACKGROUND : Glioblastoma ( GBM ) is the most common primary malignant human brain tumor with a poor prognosis . - pubmed
MATERIAL AND METHODS : 199 patients with primary GBM consecutively operated and histologically reviewed according to the 2007 WHO scheme , were included . - pubmed
RESULTS : Mean age of the GBM patients at diagnosis was 62 years ( range 21 - 84 ) . - pubmed
In addition , females , tumors with angiocentric growth , with pseudopalisades , or without lymphocyte infiltration were related to shorter survival in univariate analyses ( p & lt ; 0.05 ) . - pubmed
CONCLUSION : Our findings confirm the strong prognostic value of age , treatment , performance score , and localization for glioblastoma patients . - pubmed
Outcomes after single lung transplantation in older patients with secondary pulmonary arterial hypertension . - pubmed
Neuralgia - inducing cavitational osteonecrosis in a patient seeking dental implants . - pubmed
Cytotoxicity studies of DL - Qdots bearing carboxyl groups ( DL - Qdots - COOH ) were carried out against human cervical ( HeLa ) cancer cells to elicit no apparent toxicity even at high concentrations of 300 mug mL(-1 ) and 24 h of incubation . - pubmed
To demonstrate their potential biomedical application , DL - Qdots - COOH were further conjugated with folate for staining in HeLa , human liver carcinoma ( HepG2 ) , and human breast ( MCF-7 ) cancer cells . - pubmed
Proteomic analysis of arsenic - exposed zebrafish ( Danio rerio ) identifies altered expression in proteins involved in fibrosis and lipid uptake in a gender - specific manner . - pubmed
Despite widespread intervention efforts to curtail the spread of HIV , heterosexual transmission of HIV continues to drive the HIV / AIDS epidemic in the United States , especially among women . - pubmed
The aim of the study was to investigate the difference in clinical features of type 2 diabetic patients with and without visceral fat accumulation , focusing on vascular complications and changes in BMI . - pubmed
METHODS : We enrolled 88 Japanese hospitalized type 2 diabetic patients . - pubmed
RESULTS : Hypertension , dyslipidemia and cardiovascular diseases were significantly more in the patients with abdominal obesity . - pubmed
The prevalence of cardiovascular disease in the non - obese patients ( BMI & lt ; 25 kg / m2 ) with abdominal obesity were similar in obese patients ( BMI & gt;=25 kg / m2 ) . - pubmed
The mean BMI of the patients with abdominal obesity was & lt ; 25 kg / m2 at 20 years of age , but reached maximum to more than 30 kg / m2 in the course . - pubmed
Furthermore , substantial portion of the type 2 diabetic patients ( 52 % in males and 43 % in females ) were not obese at 20 year - old ( BMI & lt ; 25 kg / m2 ) , but developed abdominal obesity by the time of admission . - pubmed
CONCLUSION : These results emphasize the need to control multiple risk factors and prevent atherosclerotic disease in patients with abdominal obesity . - pubmed
Patient cases of hepatotoxicity involving the use of nefazodone , trazodone , duloxetine , bupropion , and sertraline are linked to causing death in its users . - pubmed
Antidepressant - induced liver injury can occur in the absence of identifiable , underlying risk factors such as cirrhosis and hepatitis infection ; only a few cases of hepatic injury involve patients with chronic hepatitis infection . - pubmed
After administration of treatment , of Treg content in spontaneous SAH patients increased progressively and became comparable with those in the other two groups at the third and fourth lumbar punctures . - pubmed
Spontaneous SAH patients showed significantly lower GCS , NIHSS , and VAS with shorter hospital stay than the traumatic SAH patients . - pubmed
CONCLUSION : Treg deficiency can be an important mechanism for the occurrence of spontaneous SAH , and a higher level of Treg indicates a better outcome of the patients . - pubmed
Neuroprotective effects of quetiapine on neuronal apoptosis following experimental transient focal cerebral ischemia in rats . - pubmed
A 75 - year - old Japanese man presented with pruritic blisters and macules on his trunk and extremities . - pubmed
New blisters continued to erupt during the period in which the patient used the cellulose triacetate membrane dialyzer , and even after the use of clobetasol propionate . - pubmed
Compared to the other three groups , Hcy plasma levels were reduced in early - onset ALS patients but Met levels were similar . - pubmed
Patients with atrial fibrillation have nearly twice the risk of stroke in first 30 days of starting warfarin . - pubmed
Dietary inclusion of sorghum ( Sorghum bicolour ) straw dye protects against cisplatin - induced nephrotoxicity and oxidative stress in rats . - pubmed
OBJECTIVE : This study sought to investigate the modulatory effect of dietary inclusion of Sorghum straw dye on cisplatin - induced nephrotoxicity and antioxidant status in rats . - pubmed
DISCUSSION AND CONCLUSION : The study suggests that dietary inclusion of sorghum straw dye as colorants could protect against oxidative stress and cisplatin - induced nephrotoxicity . - pubmed
The purpose of the current study was to validate the use of CT for selection against osteochondrosis in pigs by calculating positive predictive value and comparing it to the positive predictive value of macroscopic evaluation , using histological examination as the reference standard . - pubmed
The current histologically validated observations can potentially be extrapolated to diagnostic monitoring of juvenile osteochondritis dissecans in children , or to animal models of human juvenile articular cartilage injury and repair . - pubmed
OBJECTIVE : To investigate grey ( GM ) and white matter ( WM ) abnormalities and their effects on cognitive and behavioral deficits in a large , phenotypically and genotypically well - characterized cohort of classic adult ( aDM1 , age at onset > = 20 years ) or juvenile ( jDM1 , age at onset < 20 years ) patients with myotonic dystrophy type 1 ( DM1 ) . - pubmed
METHODS : A case - control study including 51 DM1 patients ( 17 jDM1 and 34 aDM1 ) and 34 controls was conducted at an academic medical center . - pubmed
RESULTS : DM1 patients showed a high prevalence of WMHs , severe regional GM atrophy including the key nodes of the sensorimotor and main cognitive brain networks , and WM microstructural damage of the interhemispheric , corticospinal , limbic and associative pathways . - pubmed
While aDM1 patients had severe patterns of GM atrophy and WM tract damage , in jDM1 patients WM abnormalities exceeded GM involvement . - pubmed
Addiction - related genes in gambling disorders : new insights from parallel human and pre - clinical models . - pubmed
We investigated whether rGT performance and associated risk gene expression in the rat 's brain could provide cross - translational understanding of the neuromolecular mechanisms of addiction in DG . - pubmed
We genotyped tagSNPs ( single - nucleotide polymorphisms ) in 38 addiction - related genes in 400 DG and 345 non - DG subjects . - pubmed
To our knowledge , the use of human genetics , pre - clinical models and gene expression as a cross - translation paradigm has not previously been attempted in the field of addictions . - pubmed
Spore mixtures of six strains of non - proteolytic C. - pubmed
The healing effect of scrophularia striata on experimental burn wounds infected to pseudomonas aeruginosa in rat . - pubmed
BACKGROUND : The cause of death in burn patients after 48 hours of hospitalization has been reported to be bacterial infections . - pubmed
This study aims to investigate the medicinal effect of the ethanolic extract of Scrophularia striata on burn wound infection in in - vivo and in - vitro in comparison with silver sulfadiazine ( SSD ) . - pubmed
RESULTS : The rate of wound healing was significantly greater in S. - pubmed
Nephrotic range proteinuria as a strong risk factor for rapid renal function decline during pre - dialysis phase in type 2 diabetic patients with severely impaired renal function . - pubmed
The predictive power of proteinuria , especially nephrotic range proteinuria , for progressive renal deterioration has been well demonstrated in diabetic patients with normal to relatively preserved renal function . - pubmed
However , little is known about the relationship between severity of proteinuria and renal outcome in pre - dialysis diabetic patients with severely impaired renal function . - pubmed
METHODS : 125 incident dialysis patients with type 2 diabetes were identified . - pubmed
RESULTS : In total , 103 patients ( 82.4 % ) had nephrotic range proteinuria . - pubmed
Compared to patients without nephrotic range proteinuria , patients with nephrotic range proteinuria showed significantly faster renal function decline ( 0.46 [ 0.24 - 1.25 ] versus 1.07 [ 0.64 - 1.54 ] ml / min/1.73 m(2 ) per month ; p = 0.007 ) . - pubmed
CONCLUSION : Nephrotic range proteinuria is the predominant renal risk factor in type 2 diabetic patients with severely impaired renal function receiving pre - dialysis care . - pubmed
CONCLUSION : Among these three strains tested , P. - pubmed
Characterization of the Prediabetic State in a Novel Rat Model of Type 2 Diabetes , the ZFDM Rat . - pubmed
At 6 - 8 weeks of age , fa / fa male rats exhibited mild glucose intolerance and severe insulin resistance . - pubmed
At 10 - 12 weeks of age , fa / fa male rats exhibited marked glucose intolerance as well as severe insulin resistance similar to that at the earlier age . - pubmed
RESULTS : Of the 142 patients with sickle cell anaemia , 110 ( 77.5 % ) had the alphaalpha+thalassaemia deletion . - pubmed
Amongst the patients older than 60 months , 15 ( 83.3 % ) of those without alphaalpha+thalassaemia had significant hepatomegaly of greater than 4 cm compared to 36 ( 45.6 % ) of those with alpha + thalassaemia ( p=0.003 ) . - pubmed
Concurrent alpha thalassemia might be a protective trait against significant hepatomegaly in sickle cell anaemia patients more than 60 months of age at Mulago hospital . - pubmed
The scales most commonly used by the therapeutic team for assessment of a patient with traumatic brain injury ( TBI ) include deficit scales , functional scales , and scales assessing quality of life . - pubmed
The purpose of this study was to establish the relationships between the particular scales used for assessment of patients with TBI . - pubmed
METHODS : This multicenter study included 159 patients with TBI . - pubmed
RESULTS : Patients with mild impairment of consciousness were most numerous in the examined group at both admission and discharge , ie , 118 ( 78.8 % ) and 134 patients ( 89.3 % ) , respectively . - pubmed
Genetically epilepsy - prone rats ( GEPRs ) and DBA/2 mice : Two animal models of audiogenic reflex epilepsy for the evaluation of new generation AEDs . - pubmed
This review summarizes the current knowledge about DBA/2 mice and genetically epilepsy - prone rats ( GEPRs ) and discusses the contribution of such animal models on the investigation of possible new therapeutic targets and new anticonvulsant compounds for the treatment of epilepsy . - pubmed
Abnormal activities of enzymes involved in catecholamine and serotonin synthesis and metabolism were reported in these models , and as a result of all these abnormalities , seizure susceptibility in both animals is greatly affected by pharmacological manipulations of the brain levels of monoamines and , prevalently , serotonin . - pubmed
Audiogenic models of epilepsy have been used not only for reflex epilepsy studies , but also as animal models of epileptogenesis . - pubmed
MI - associated blood leukocytosis correlates inversely with patient survival , yet the signals driving heightened leukocyte production after MI remain incompletely understood . - pubmed
CONCLUSIONS : Participants with chronic schizophrenia made significant cognitive gains after 50 hours of intensive computerized training delivered as a stand - alone treatment , but no improvement in symptoms or functioning . - pubmed
Inflammatory Mediators and Clinical Outcome in Patients With Advanced Heart Failure Receiving Cardiac Resynchronization Therapy . - pubmed
Antibodies from donor B cells perpetuate cutaneous chronic graft - versus - host disease in mice . - pubmed
With a murine cGVHD model using DBA/2 donors and BALB / c recipients , we have shown that wild - type ( WT ) grafts induce persistent cGVHD with damage in the thymus , peripheral lymphoid organs , and skin , as well as cutaneous T helper 17 cell ( Th17 ) infiltration . - pubmed
The aim of our study was to analyze the clinicopathological factors , compare treatment options , and evaluate outcome in patients with PT . - pubmed
The main goal of the study was to investigate whether the quantitative changes of Treg subpopulations are related to the clinical status of patients with LN . - pubmed
Fifty - four adult SLE patients divided into two groups according to their SLEDAI and renal SLEDAI scores were enrolled into the study . - pubmed
The combined experiences of the authors , including a diabetes predictive model for oral health settings , the efficacy and effectiveness of human immunodeficiency virus screening in a dental setting , the feasibility of using a decision support tool for tobacco cessation , and the effectiveness of integrating oral health education with comprehensive health services for people living with human immunodeficiency virus , have contributed to this concept . - pubmed
Predictors of pain response in patients undergoing endoscopic ultrasound - guided neurolysis for abdominal pain caused by pancreatic cancer . - pubmed
RESULTS : A good pain response was obtained in 77.7 % and 67.9 % of patients at 1 and 4 weeks , respectively . - pubmed
We hereby sought to explore the association of inter - arm BP difference with ICAS and ECAS in stroke - free hypertensive patients in Chinese population . - pubmed
Appraisal of inflammation - based prognostic scores in patients with unresectable perihilar cholangiocarcinoma . - pubmed
METHODS : The modified Glasgow Prognostic Score ( mGPS ) , Neutrophil Lymphocyte Ratio ( NLR ) , Platelet Lymphocyte Ratio , and Prognostic Nutritional Index , were retrospectively assessed in 219 patients with unresectable perihilar cholangiocarcinoma . - pubmed
CONCLUSIONS : Both mGPS and NLR are independent prognostic factors and pivotal in refining patient stratification in unresectable perihilar cholangiocarcinoma . - pubmed
Effects of Taekwondo intervention on balance in children with autism spectrum disorder . - pubmed
The purpose of this study was to investigate the effects of an 8 - week Taekwondo ( TKD ) intervention on balance in children with autism spec - trum disorder ( ASD ) . - pubmed
A total of 14 children with ASD participated in this study . - pubmed
KSHV prevalence is high in several populations with high prevalence of HIV , leading to increased risk of development of Kaposi ' s sarcoma ( KS ) . - pubmed
While current assays are reliable for detecting antibodies to KSHV , none are routinely utilized to identify individuals with KSHV infection and thus at increased risk for KS due to assay complexity , lack of access to testing , and cost , particularly in resource - limited settings . - pubmed
This study demonstrates assay performance by measuring antibody reactivity for KSHV and HIV-1 in a collection of clinical specimens from patients with biopsy - proven KS and sourced negative controls . - pubmed
The KSHV assay correctly identified 155 of 164 plasma samples from patients with biopsy - proven KS and 85 of 93 KSHV antibody ( Ab)-negative samples for a sensitivity of 95.1 % and specificity of 91.4 % . - pubmed
Depending on the context , after sensing environmental antigens , commensal microorganisms , pathogenic agents , or antigens from the diet , dendritic cells may drive either different effector adaptive immune responses or tolerance , avoiding tissue damage . - pubmed
Majority of patients ( 80 % ) experienced similar pain during axillary view compared to contralateral MMG . - pubmed
The goal of the present study was to investigate the effects of long - term and short - term consumption of quercetin , ( -)- epicatechin , and ibuprofen on the lifespan , resistance to stress factors ( paraquat , hyperthermia , gamma - radiation , and starvation ) , as well as age - dependent physiological parameters ( locomotor activity and fecundity ) of Drosophila melanogaster . - pubmed
BACKGROUND : Detection of cancer and subsequent chemotherapy can lead to clinical depression in many cancer patients . - pubmed
OBJECTIVES : The study was conducted to find out the extent of depression in cancer patients undergoing chemotherapy and determine the factors associated with depression . - pubmed
A novel dimorphic pathogen , Emergomyces orientalis ( Onygenales ) , agent of disseminated infection . - pubmed
When we used a mouse tumor implantation model to evaluate pCD63 - OVA as a therapeutic vaccine , the EV - delivered DNA vaccination significantly inhibited tumor growth compared with the control DNA vaccinations . - pubmed
METHODS : We applied US Food and Drug Administration ( FDA ) and insurance eligibility criteria for ALI and EVO to 1090 hypercholesterolemic patients serially referred over 3 years who then received & gt;=2 months maximal - tolerated dose of standard - of - care LDL cholesterol - lowering therapy ( MTDLLT ) with follow - up LDLC & gt;=70 mg / dL. - pubmed
RESULTS : Of the 1090 patients , 140 ( 13 % ) had HeFH by clinical diagnostic criteria and/or CVD with LDLC & gt;100 mg / dL despite & gt;=2 months on MTDLLT , meeting FDA insurance criteria for ALI or EVO therapy . - pubmed
Recent observational studies have reported that patients with low circulating levels of vitamin D experience larger infarct volumes and worse functional outcomes after ischemic stroke compared to those with sufficient levels . - pubmed
Male C57Bl6 mice ( six week old ) were assigned to either a control or vitamin D deficient diet for four weeks prior to stroke . - pubmed
METHODS : A total of 13 male patients underwent IRE of focal low - risk PCa and were included in this analysis . - pubmed
PURPOSE : To systematically analyse the differences between cycloplegic and noncycloplegic refractive errors ( RE ) in children and to determine if the predictive value of noncycloplegic RE in categorizing RE can be improved . - pubmed
PATIENTS AND METHODS : Electrochemotherapy with bleomycin was performed on 17 hepatocellular carcinomas in 10 patients using a previously established protocol . - pubmed
CONCLUSIONS : Electrochemotherapy of hepatocellular carcinoma proved to be a feasible and safe treatment in all 10 patients included in this study . - pubmed
Electrochemotherapy is predominantly applicable in patients with impaired liver function due to liver cirrhosis and/or with lesions where a high - risk operation is needed to achieve curative intent , given the intra / perioperative risk for high morbidity and mortality . - pubmed
This is limited by correct surgical technique , the age of the patient , delay from the time of injury and the mechanism or localization of the injury . - pubmed
In this secondary intention - to - treat analysis , we assessed the change in estimated glomerular filtration rate ( eGFR ) over a 44 - month follow - up period in patients with ( n=3784 ) and those without ( n=4615 ) diabetes . - pubmed
Compared with patients treated with enalapril , those treated with sacubitril / valsartan had a slower rate of decline in eGFR ( -1 3 vs -1 8 mL / min per 1 73 m2 per year ; p<0 0001 ) , and the magnitude of the benefit was larger in patients with versus those without diabetes ( difference 0 6 mL / min per 1 73 m2 per year [ 95 % CI 0 4 - 0 8 ] in patients with vs 0 3 mL / min per 1 73 m2 per year [ 0 2 - 0 5 ] in those without diabetes ; pinteraction=0 038 ) . - pubmed
The incremental benefit of sacubitril / valsartan in patients with diabetes was no longer apparent when changes in eGFR were adjusted for urinary cyclic guanosine monophosphate ( p=0 41 ) . - pubmed
Purpose : This study aimed at investigating the long - term outcomes of oxaliplatin and capecitabine ( XELOX ) administered concurrently with preoperative radiation and extended to the resting period in patients with high - risk locally advanced rectal cancer ( LARC ) . - pubmed
Twelve ( 26.7 % ) patients developed local recurrence or distant metastasis , including 10 ( 22.2 % ) patients developing distant metastasis only , 1 ( 2.2 % ) patient local recurrence only , and 1 ( 2.2 % ) patient both local recurrence and distant metastasis . - pubmed
Of the 296 betaHS , 220 ( 74 % ) were GAS , 52 ( 17.5 % ) were Group G streptococci and 11 ( 3.7 % ) , 10 ( 3.3 % ) and three ( 1 % ) were Group B streptococci , Group C streptococci and Group F streptococci , respectively . - pubmed
Berberine ( BBR ) , an active component of a Chinese herb Coptis chinensis French , has been shown to have anti - inflammatory properties through suppressing macrophage migration in various inflammation animal model . - pubmed
The goal of this study was to examine BBR 's effect on inflammation and IAs formation in a rodent aneurysm model . - pubmed
A rodent aneurysm model was induced in 5 - week - old male Sprague Dawley ( SD ) rats by intracranial surgery , then these rats were orally administrated 200 mg / kg / day BBR for 35 days . - pubmed
Urinary and Plasma Metabolomics Identify the Distinct Metabolic Profile of Disease State in Chronic Mouse Model of Multiple Sclerosis . - pubmed
Graphical Abstract Untargeted urinary metabolomics of a chronic mouse model of multiple sclerosis identified Phenylalanine , tyrosine & amp ; tryptophan metabolism as the significantly altered metabolic pathway . - pubmed
Speech Impairment in Boys With Fetal Alcohol Spectrum Disorders . - pubmed
Purpose : This study set out to chart the speech and speech motor characteristics in boys with FASD to profile the concomitant speech impairment and identify possible underlying mechanisms . - pubmed
Method : Ten boys with FASD ( 4.5 - 10.3 years old ) and 26 typically developing children ( 4.1 - 8.7 years old ; 14 boys , 12 girls ) participated in the study . - pubmed
Results : The boys with FASD showed reduced scores on all tasks as well as a deviant pattern of correlations between production and perception tasks and intelligibility compared with the typically developing children . - pubmed
Conclusions : Findings indicate that the speech impairment in boys with FASD results from a combination of deficits in multiple subsystems and should be approached as a disorder rather than a developmental delay . - pubmed
Considerable progress has been made in the development of approaches for HIV incidence estimation based on a cross - sectional survey for biomarkers of recent infection . - pubmed
METHODS : Patients who called for EMS due to pain in a part of western Sweden were included . - pubmed
Attention - deficit / hyperactivity disorder ( ADHD ) is a neurodevelopmental disorder that affects approximately 8%-12 % of children worldwide . - pubmed
Although evidence - based treatments can reduce ADHD symptoms in a substantial portion of affected individuals , there is yet no curative treatment for ADHD . - pubmed
Besides , OA rats showed obvious synovial tissue hyperplasia , inflammation and cartilage injury of femoral condyle , as well as increased inflammation and cartilage injury scores , and apoptosis of synoviocytes and chondrocytes . - pubmed
Alcohol Extracts From Ganoderma lucidum Delay the Progress of Alzheimer ' s Disease by Regulating DNA Methylation in Rodents . - pubmed
Age - related changes in methylation are involved in the occurrence and development of tumors , autoimmune disease , and nervous system disorders , including Alzheimer ' s disease ( AD ) , in elderly individuals ; hence , modulation of these methylation changes may be an effective strategy to delay the progression of AD pathology . - pubmed
In this study , the AD model rats were used to screen the main active extracts from the mushroom , Ganoderma lucidum , for anti - aging properties , and their effects on DNA methylation were evaluated . - pubmed
We investigated the waveform patterns of automatically detected high - frequency oscillations in 13 patients with epilepsy and 5 control subjects , with an average of 73 subdural and intracerebral electrodes recorded per patient . - pubmed
Consistently in all patients , the stereotypical high - frequency oscillations with the highest degree of waveform similarity were localized within the seizure onset zones only , whereas the channels generating high - frequency oscillations embedded in random waveforms were found in the functional regions independent of the epileptogenic locations . - pubmed
Giant aneurysm arising from anomalous branch of the middle cerebral artery in a paediatric patient : case report and review of literature . - pubmed
Conclusion : Motivational interviewing promotes treatment adherence among patients with chronic obstructive pulmonary disease . - pubmed
Here we model chronic intestinal damage in zebrafish larvae using the nonsteroidal antiinflammatory drug ( NSAID ) Glafenine . - pubmed
However , there are few reported cases of super - refractory status epilepticus in children . - pubmed
We illustrate that super - refractory status epilepticus can be the first manifestation of small vessel cPACNS in previously healthy children and that symptomatic management of seizures with concurrent immunosuppression to treat the underlying pathology resulted in favorable neurologic outcomes . - pubmed
Cancer patients are at increased risk of developing thrombosis , comorbidity that has been associated with increased neutrophil counts and the formation of neutrophil extracellular traps ( NETs ) . - pubmed
The aim of this study was to investigate whether artemisinin derivatives artesunate and dihydroartemisinin could enhance the immunogenicity of inactivated rabies virus in mice . - pubmed
Administration of artesunate or dihydroartemisinin by intramuscular injection at a dose of 5 mg / kg did not cause body weight loss and unusual symptoms in mice . - pubmed
Tremendous progress has been made over the past three decades in the fight against the human immunodeficiency virus ( HIV ) epidemic ; however , children experienced substantial physical and psychosocial effects of HIV infection . - pubmed
Giant cell arteriitis ( GCA ) is the most common systemic vasculitis in patients > = 50 years . - pubmed
Our previous studies showed that matrine ( MAT ) , a natural alkaloid component extracted from the Sophora root , has beneficial effects in EAE through immunomodulation . - pubmed
The sample consisted of 66 preterm infants of both sexes , aged 18 - 36 months , divided into two groups : AIG Group 39 neonates with weight appropriate to the gestational age , 26 with normal hearing and 13 with altered hearing ; and PIG group 27 neonates small for gestational age , 18 with normal and 9 with altered hearing . - pubmed
Although its history began more than 30 years ago , it remains one of the most used drugs in children with a leading role in the medical care of children with allergic diseases . - pubmed
Cetirizine use is licensed for paediatric patients for the treatment of allergic rhinitis , and chronic spontaneous urticaria , in Europe in children older than 2 years old and in the USA in children older than 6 months old . - pubmed
Compounds 1 and 6 also exhibited moderate antibacterial activities against sensitive ( ATCC 29213 ) and drug - resistant ( ATCC 700699 ) strains of Staphylococcus aureus . - pubmed
As the biomedical community races to disentangle the unknowns associated with severe acute respiratory syndrome coronavirus 2 , the virus responsible for causing coronavirus disease , the link between diminished immune function and individuals with obesity raises important questions about the possibility for greater viral pathogenicity in this population . - pubmed
Patients were evaluated for postoperative pain , swelling , and trismus . - pubmed
RESULTS : We identified 15 patients ( 4 male , 11 female ; mean age 53.7 years ) who had RYGB on average 11.7 years ( range 1 - 32 ) years before diagnosis of biliary obstruction . - pubmed
Fourteen patients reported abdominal pain , 5 had nausea / emesis , 12 had elevated liver function tests , and 6 had ascending cholangitis . - pubmed
Twenty - six studies including 23 826 patients with or without PAD who underwent ERCP were evaluated . - pubmed
This Valproate - D - Nanogel was prepared through copolymerizing carboxymethyl chitosan with diallyl disulfide and subsequent grafting with valproate to reverse the drug - resistance in cisplatin - resistant human lung adenocarcinoma cancer . - pubmed
The whole - genome sequencing ( WGS ) allowed evaluating the genome stability of BCG strains and the impact of spontaneous heterogeneity in seed and commercial lots on the efficacy of BCG - vaccines in different countries . - pubmed
Sequence variations in several genes of seed lot 361 did not alter the genomic stability and viability of the vaccine and appeared accumulated in isolates during the survival in the human organism . - pubmed
The dysregulation of miR-451a was revealed both in primary tumors and in patients ' sera . - pubmed
The study of functional and structural changes in these components of the eye will provide useful information to identify subjects with diabetes at risk of diabetic peripheral neuropathy and dementia . - pubmed
PATIENT CONCERNS : A 77 - year - old man with diplopia was referred to our department by an opthomologist who had diagnosed the patient with right abducens nerve palsy . - pubmed
Meditation for Improved Clinical Outcomes in Patients with Implantable Defibrillators for Heart Failure- Pilot Study . - pubmed
We hypothesized that meditation by reducing emotional reactivity would have beneficial effect in reducing arrhythmias compared to control patients . - pubmed
Methods : Patients known to have CHF and implantable cardioverter defibrillators ( ICD ) were randomized to Vipassana meditation or usual care control group . - pubmed
Results : Patients ( n=25 , 65 % male , mean LVEF 25 % , HTN 38 % , Diabetes 12 % , coronary artery disease 38 % , NYHA class 2.2 ) were followed for 79 + 36 months . - pubmed
Conclusions : In this first pilot study of meditation in CHF patients with ICD , during long term follow up , there is a trend for improved survival and reduced arrhythmias in patients randomized to meditation . - pubmed
Method Thirty - six monolingual English - speaking children aged 4 and 5 years , half with SSD and half with typical speech and language skills , participated in this study . - pubmed
Modified surgical treatment for a patient with neurofibromatosis scoliosis : A case report . - pubmed
CASE SUMMARY : A 44 - year - old woman presented with progressive kyphosis for more than 10 years and low back pain for 2 years . - pubmed
CONCLUSION : For this patient with severe deformity , the correction treatment of Ponte osteotomy followed by satellite rod technique in the region of the apical vertebra and the technique of pedicle screws and dual iliac screws had been applied , and successful clinical outcomes were achieved . - pubmed
Spatial navigation and dual - task performance in patients with Dementia that present partial dependence in instrumental activity of daily living . - pubmed
However , more low - cost assessments are necessary to better understand the process of IADL in patients with Dementia . - pubmed
Objective : To compare cognitive , motor and cognitive - motor performance at different stages of dependence on IADL in patients with Dementia . - pubmed
Methods : Dementia patients ( n = 53 , age range : 63 - 94 ) and healthy older adults ( n = 39 , age range : 62 - 97 ) were included , and those with Dementia were separated into IADL 1 ( n = 18 ) , IADL 2 ( n = 17 ) , IADL 3 ( n = 18 ) . - pubmed
Also , an effect size ( ES ) has been applied to evaluate differences among the dementia groups while the healthy older adults were used as a reference group . - pubmed
Transcriptome and clinical survival information of HCC patients was obtained from The Cancer Genome Atlas database . - pubmed
Overall , a novel nomogram to predict the 1 - year and 3 - year OS of HCC patients was developed , which shows good reliability and accuracy , for use in improved treatment decision - making . - pubmed
In vivo studies indicated that the labeled platelets accumulated at the plague of atherosclerotic rabbits . - pubmed
However , postmortem changes could not account for the large differences observed in the levels of GHB found in bovine caudate and those found in guinea - pig , monkey and human caudate . - pubmed
Delayed type hypersensitivity to Staphylococcus aureus peptidoglycan in guinea pigs . - pubmed
Skin hypersensitivity to Staphylococcus aureus peptidoglycan in guinea pigs was studied . - pubmed
Nonsensitized guinea pigs and animals sensitized with emulsion of 1 mg or 100 microgram of peptidoglycan with complete or incomplete FREUND 's adjuvant exhibited distinct immediate skin hypersensitivity . - pubmed
After inoculation of healthy guinea pigs with a live culture , the number of monocytes doubles and remains at this level up to the 11th day after the infection . - pubmed
A venal injection of Salmonella abortus ovis allergen to sensibilized guinea pigs , possessing a dermal - allergic reaction , leads to a marked decrease in the number of monocytes in the blood on the 2nd and 6th hrs after application of the allergen , while on the 24th h their number regains the level prior injection . - pubmed
Malformed spermatids and spermatozoa in the testes , epididymes , and ejaculates of 29 apparently healthy men and in 171 patients suffering from different andrological diseases were investigated with the electron microscope . - pubmed
Reevaluation of the plasticity in the rat supraoptic nucleus after chronic dehydration using immunogold for oxytocin and vasopressin at the ultrastructural level . - pubmed
Intrapapillary linear collections of contrast medium ( ie , three or more linear collections of contrast material within a papilla ) were found in 10 ( 9.5 % ) of the 105 patients with renal stone disease and two ( 1.0 % ) of the 195 patients without nephrolithiasis ( P less than .001 ) . - pubmed
Effects of nifedipine versus hydralazine on sympathetic activity and cardiac function in patients with hypertension persisting on diuretic plus beta - blocker therapy . - pubmed
In patients with hypertension persisting on combined diuretic and beta - blocker therapy , the effects of an additional 9 - week therapy with a calcium antagonist ( nifedipine ) versus a classical arterial vasodilator ( hydralazine ) were compared for changes in blood pressure ( BP ) , plasma catecholamines ( n = 15 ) , and left ventricular ( LV ) systolic and diastolic function ( n = 6 ) . - pubmed
Of 34 patients with apparently isolated cerebellar lesions , postoperative outcome was good in 79 % . - pubmed
Twelve ( 23 % ) of the patients definitely had von Hippel - Lindau disease ( VHLD ) . - pubmed
All patients with an apparently isolated CNS haemangioblastoma should be investigated for evidence of von Hippel - Lindau disease . - pubmed
The patient had infectious polyarthritis caused by Haemophilus influenzae , which is a very rare cause of acute polyarthritis in children older than 2 years . - pubmed
In 265 patients of acute myocardial infarction ( AMI ) heparin followed by warfarin sodium was used routinely whenever there was no contraindication to the drug . - pubmed
Another 265 patients of AMI having identical clinical profiles were taken as control and neither any anticoagulant nor any antiplatelet agent was used in them . - pubmed
One patient developed sternal dehiscence ; wound complications or incompatibility with the suture material did not occur . - pubmed
Isoprinosine enhances PHA responses and has potential effect on natural killer cell ( NK ) activity of uremic patients in vitro . - pubmed
We studied the effect of an immuno - stimulating agent , isoprinosine , which is being marketed as an antiviral drug , on some immune functions in vitro in 14 uremic patients treated by hemodialysis and in 10 healthy controls . - pubmed
Our results motivate a clinical study with isoprinosine in uremic patients at the risk of virus infection . - pubmed
A single dose of the DNA - binding cytostatic agent bleomycin ( 100 micrograms / g body weight , subcutaneously ) was given to 10 - day - old rats to study unscheduled repair DNA synthesis in nucleolar and in bulk nuclear chromatin of postmitotic Purkinje neurons . - pubmed
The greatest benefit is realized in patients treated within the first few hours of onset of acute myocardial infarction . - pubmed
All previous patients with metastatic Merkel cell carcinoma to the brain died within two months of the diagnosis . - pubmed
We use this case to discuss possible routes of metastatic dissemination and to review the treatment options in patients with distant metastatic disease . - pubmed
To our knowledge , this is the first reported case of presumed choroidal metastasis of Merkel cell carcinoma and the longest documented survival in a patient with brain involvement . - pubmed
The case history of a 41 - year - old man with a hibernoma in the scapular area is presented . - pubmed
We have utilized DNA transfer and recombinant DNA techniques to probe DNA double - strand break repair in the human ionizing radiation - sensitive genetic syndrome ataxia - telangiectasia ( A - T ) . - pubmed
Effects of clofibrate on hyperlipidemia induced by polychlorinated biphenyls and elimination of polychlorinated biphenyls accumulated in rat tissues . - pubmed
Our culture system may be useful in investigating the direct effects produced on human trabecular meshwork by photocoagulation and various agents , for example anti - glaucoma drugs , steroids and viscoelastic materials . - pubmed
All strains of staphylococci , streptococci , enterococci and Listeria monocytogenes were inhibited at concentrations less than or equal to 2 micrograms / ml . - pubmed
The myoelectrical activity of the large intestine of fed and fasted rats was recorded with chronically implanted nichrome wire electrodes after destruction of the spinal cord , after spinal cord transection , and after spinal anaesthesia . - pubmed
The effect of training procedures on fixed - interval responding following septal lesions in rats . - pubmed
Two experiments were conducted to assess the effects of training procedures on fixed - interval ( FI ) performance of rats with septal lesions . - pubmed
The results suggest that septal lesions result in a transient disruption in the FI performance of rats with previous FI experience without affecting the acquisition of appropriate FI behavior . - pubmed
Mesenteric adenitis was diagnosed histologically in three patients and Y. - pubmed
Possible application to problems of human genetic disease are indicated . - pubmed
Camping rewarding for diabetic children . - pubmed
Furthermore , experimental studies suggest that the growth of signet - ring cell carcinoma transplanted on nude mice depends on sex hormone . - pubmed
Based on these observations , the clinical trial of chemo - endocrine therapy after gastrectomy for female patients with diffuse carcinoma of the stomach has been performed in our hospital since 1980 . - pubmed
This result suggests that the chemo - endocrine therapy after gastrectomy may be a new hopeful adjuvant in female patients with diffuse carcinoma of the stomach . - pubmed
The vector and soil transmitted parasitic infections produce a highly diverse group of diseases in terms of the importance of their impact upon human populations and in terms of the control methods that might limit that impact . - pubmed
Twenty - seven patients with angina pectoris , 24 with postmyocardial infarction angina and 7 with normal coronary arteries were examined by exercise thallium-201 emission computed tomography ( SPECT ) and planar scintigraphy . - pubmed
A patient was referred for investigation of heavy bleeding after surgery . - pubmed
We studied the clinicopathologic and neuro - ophthalmic manifestations of central nervous system toxoplasmosis in two patients who were being treated with immunosuppressive chemotherapy , one for renal transplantation and the other for systemic lupus erythematosis . - pubmed
Although immune complexes are detectable in a high percentage of bullous pemphigoid patients , their role in this disease may be epiphenomenal rather than pathogenetic , merely reflecting the presence of autoantibody and soluble antigen . - pubmed
Myocardial ischemia in dogs with gastric dilatation - volvulus . - pubmed
The records of 10 patients with cavernous choroidal hemangiomas were reviewed . - pubmed
In contrast to the originally described patient , who had a severe hemorrhagic diathesis , our proband had only a mild bleeding tendency . - pubmed
Intracardiac and/or transesophageal electrophysiological studies were performed on seven infants ( group 1 , mean age 2 months ) and four children ( group 2 , mean age 9 y ; study 1 ) , and documented orthodromic atrioventricular tachycardia in all cases . - pubmed
The structure of this 190 - residue domain , which was expressed in and isolated from Escherichia coli , is essentially identical to the structure of the catalytic domain within whole diphtheria toxin determined at pH 7.5 . - pubmed
Is it worth doing barium enemas on patients with unexplained iron deficiency anaemia ? - pubmed
The incidence on double contrast barium enema ( DCBE ) of carcinomas and polyps & gt ; 1 cm in size was compared in 92 patients with iron deficiency anaemia and a group of randomly obtained non - anaemic controls . - pubmed
During hemorrhage , DPSPX treatment significantly increased PRA levels ( P & lt ; .039 ) in rats with intact kidneys . - pubmed
DMPA has been tested in short- and long - term toxicity studies in rodents , rabbits , and monkeys . - pubmed
In addition , human IL-8 - R mRNA could be detected for the first time in human melanoma cells . - pubmed
Flocculent strains of brewing yeast grow and ferment as single cells and flocculate in the stationary phase of growth . - pubmed
The presence of carbohydrate receptors , outer - chain mannan side - branches , was monitored throughout growth of flocculent and non - flocculent strains of Saccharomyces cerevisiae , with particular attention to the growth phases where flocculation is normally developed . - pubmed
While considerable variation was found in coflocculation and concanavalin A aggregation between strains , little or no change in receptor availability was found throughout the growth of all yeast strains . - pubmed
The patient , a 65 - year - old man , fell into shock , due to acute myocardial infarction and received cardiopulmonary resuscitation at home immediately . - pubmed
These results taken together indicate that swine may be a good animal model for human Ad5 lung infection to aid in the evaluation of candidate adenovirus vaccines and that Ad5 may be suitable as a recombinant viral vaccine or for other applications in swine . - pubmed
Oral contraceptive agents are not contraindicated in women with epilepsy ; however , the contraceptive failure rate increases fourfold if patients are being treated concurrently with enzyme - inducing antiepileptic drugs . - pubmed
The dosage should be adjusted if the patient 's seizures are increasing . - pubmed
Women with epilepsy may have disease - related or treatment - related menstrual dysfunction , complications of pregnancy ( slightly increased risk of toxemia and fetal loss ) , endocrine dysfunction , appearance changes ( a general coarsening of facial features with long - term administration of antiepileptic agents ) , and psychosocial maladjustment . - pubmed
Although control of seizures remains the primary goal of treating women with epilepsy , the widening choice of antiepileptic drugs may facilitate optimal management of secondary and gender - specific complications . - pubmed
Phenotypic and genotypic characterization of spotted fever group Rickettsiae isolated from Catalan Rhipicephalus sanguineus ticks . - pubmed
Eighty - nine Rhipicephalus sanguineus ticks and 21 Rhipicephalus bursa ticks collected in Catalonia were tested by the hemolymph test to establish their infection rate with spotted fever group rickettsiae . - pubmed
PCR followed by restriction fragment length polymorphism analysis showed that the six strains were identical and were characterized by the same restriction profiles as a strain , Mtu5 , previously isolated from Rhipicephalus turanicus ticks in the South of France . - pubmed
Phylogenetic analysis showed that this new rickettsial sero- and genotype , which will be named the " Catalan strain , " is closely related to Rickettsia massiliae . - pubmed
We successfully performed a total correction which consisted of a resection of the intra - left atrial fibrous membrane , reconstruction of the LSVC return pathway to the right atrium with PTFE graft , atrial partition with a bovine pericardial patch and the conotruncal repair for Tetralogy of Fallot . - pubmed
We have reviewed the clinical documentation of all the patient aged 65 or more admitted to our hospital because of recent onset typical or atypical angina , who underwent an exercise tolerance test and coronary angiography . - pubmed
At coronary angiography 6 patients showed non obstructive lesions ( range : 20 - 40 % ) and only 5 had normal findings : 2 of these patients showed gastro - intestinal disease which could be considered as possible trigger of chest pain . - pubmed
We conclude that syndrome X may appear also in the elderly with the same clinical features already described in younger patients . - pubmed
The toxicity of G28 - 5 sFv - PE40 was examined in SCID mice , rats , and monkeys , with the maximum tolerated dose being 0.48 , 1.0 , and 1.67 mg / kg , respectively . - pubmed
Although transgenic proteins accumulated in low amounts in all the plant lines analysed , accumulation of the mutant non - processed protein form was greatly increased in plants following infection with TEV , but not TMV , apparently as a consequence of protein stabilization . - pubmed
All patients had metastatic disease within cervical lymph nodes at presentation and eventually developed distant metastases . - pubmed
Pneumolysin - deficient mutant strains of Streptococcus pneumoniae are known to cause less - severe sepsis than wild - type pneumococcal strains that produce pneumolysin . - pubmed
This difference is associated with greater host resistance in mice infected with the pneumolysin - deficient strains . - pubmed
The concentrations of S , B , Al , Cr , Fe , Si , Ti , and Zn correlated with injury in cell membranes of R. - pubmed
Multivariate logistic regression analyses showed that presence of anti - HCV , male gender , and history of liver disease were associated with the presence of liver dysfunction , and that age of more than 40 years and a particular district were associated with the presence of anti - HCV . - pubmed
The incidence of liver dysfunction was significantly higher in HCV RNA - positive men than women ( 32 , or 66.7 % versus 22 , or 30.6 % ) ( P & lt ; 0.05 ) . - pubmed
These findings suggest that : ( 1 ) HCV was correlated with the high mortality rate from liver diseases , ( 2 ) there were district - related differences in the incidence of HCV , and ( 3 ) the lower frequency of elimination of HCV from men may explain why they showed a high mortality from liver disease . - pubmed
[ Increasing the efficacy of treating patients with extensive ovarian cancer by using laferon ] . - pubmed
Patients with stage III - IV cancer of the ovary have been shown to derive a greater benefit from conventional complex treatments involving adjuvant laferon therapy . - pubmed
Signs of glaucoma in rhesus monkeys from a restricted gene pool . - pubmed
The aetiologic agent of avian colibacillosis is Escherichia coli . - pubmed
Colibacillosis is a disease that causes mortality and production performance problems in chickens which results in economic losses for the poultry industry . - pubmed
In the battery study , subcutaneous administration of LPS to one - day - old broiler cockerels caused a significant reduction ( P & lt ; 0.003 ) in all parameters of colibacillosis evaluated , i.e. - pubmed
However , in the floor - pen study , subcutaneous administration to one - day - old broiler chicks resulted in a numerical , but not statistically significant reduction ( P & lt ; 0.1 ) in mortality associated with colibacillosis . - pubmed
Favorable combination effects of the leukotriene synthesis inhibitor BAY X 1005 and dexamethasone on edema formation in the arachidonic acid - induced mouse ear inflammation test . - pubmed
The effects of a combination of the leukotriene synthesis inhibitor ( LSI ) BAY X 1005 with the glucocorticosteroid dexamethasone were studied in the arachidonic acid ( AA)-induced mouse ear inflammation test ( AA - MEIT ) . - pubmed
Sildenafil for women patients with antidepressant - induced sexual dysfunction . - pubmed
In an open study , sildenafil ( Viagra ) was prescribed for nine women outpatients who reported sexual dysfunction induced by antidepressant medication , primarily selective serotonin reuptake inhibitors . - pubmed
The nine patients , all of whom had experienced either anorgasmia or delayed orgasm with or without associated disturbances , reported significant reversal of sexual dysfunction , usually with the first dose of 50 mg of sildenafil . - pubmed
We herein report two patients with left atrial myxoma who needed an emergency operation . - pubmed
Case 1 was a 48 - year - old woman who was injured in a traffic accident and underwent an operation for a right leg fracture . - pubmed
MATERIALS AND METHODS : Two hundred eighty - one patients underwent 306 sonographically guided compression procedures on 297 groin pseudoaneurysms after femoral artery catheterization . - pubmed
The medical records , cardiac catheterization reports , and sonographic images were reviewed to determine patient demographics , type of catheterization procedure performed , sheath size , access site , interval from sheath removal to compression , anticoagulation status , pseudoaneurysm dimensions , complications , and follow - up information . - pubmed
Eleven complications ( 3.6 % ) occurred , including three patients with rupture during compression . - pubmed
CASE DESCRIPTION : A 63 - year - old woman presented with left putaminal hemorrhage . - pubmed
diphtheriae strains of biovar gravis , ribotype M11 , dominated in the 40 - 60 years and C. - pubmed
All patients admitted to the coronary care unit with suspected acute coronary syndromes were evaluated by serial electrocardiography and blood draws on admission and at 4 and 12h from admission . - pubmed
These data will be used for future studies of differential protein expression in mouse models of neurological disorders . - pubmed
RESULTS : We showed previously that wild - type mice developed a mild form of EAE with complete recovery . - pubmed
We also induced EAE by passive transfer of MOG(35 - 55)-reactive lymph node cells , and this disease was aggravated by sympathectomy in both wild - type and knockout animals . - pubmed
To study the effect of chemotherapy on bone marrow angiogenesis in patients with multiple myeloma , we used two methods to evaluate bone marrow angiogenesis in patients with newly diagnosed multiple myeloma , comparing these findings with those from bone marrow obtained after standard chemotherapy . - pubmed
We conclude that the degree of bone marrow angiogenesis is a prognostic marker in patients with multiple myeloma and does not decrease significantly after therapy . - pubmed
[ Therapy of fractures of the thigh in children ] . - pubmed
Isolation of crystalline aldosterone from the urine of a child with the nephrotic syndrome . - pubmed
Essential hypertension in humans may develop through a combination of genetic and environmental factors . - pubmed
During mammalian fertilization , sperm adhere to the extracellular coat of the egg , or zona pellucida , in a species - specific manner . - pubmed
In conclusion , this model provides a robust economic analysis of the cost of lung cancer management , and will be useful for assessing the economic consequences of future changes in patient management . - pubmed
Acupuncture was used to treat a 69 - year - old man for bilateral ankle pain related to his rheumatoid arthritis . - pubmed
RESULTS : Eleven ( 27 % ) of the patients with type A hematoma and 1 ( 2 % ) of the patients with type B hematoma underwent early surgical intervention . - pubmed
Others were treated medically , and the overall hospital mortality was 7 % for patients with type versus 2 % for patients with type B intramural hematomas of the aorta ( P = .315 ) . - pubmed
Twenty - three patients , 9 ( 22 % ) with type A and 14 ( 26 % ) with type B intramural hematomas of the aorta , underwent late surgical intervention during the follow - up period , and there were no hospital deaths . - pubmed
A total of 23 patients died during the follow - up period , including 6 of intramural hematoma of the aorta - related deaths ( 3 in the type A group and 3 in the type B group ) . - pubmed
Tick - borne fever as a cause of abortion in sheep . - pubmed
Physician should be alert to the occurrence of hematogenous disseminated tuberculosis , especially in immune compromised patients with long - term fever and systemic injury . - pubmed
Patients , 50 - 89 years of age , with hip fracture ( cases ) were ascertained through surveillance of 18 Utah hospitals during 1997 - 2001 . - pubmed
A nano - view of West Nile virus - induced cellular changes during infection . - pubmed
An understanding of the ecological factors that regulate natural populations of Aedes aegypti mosquitoes can improve control and reduce the incidence of dengue ( DF ) and dengue hemorrhagic fever ( DHF ) in tropical areas . - pubmed
We used starvation resistance ( number of days alive without food ) as an indicator of the feeding history in third - instar Ae . - pubmed
If resistance to starvation and adult mass of field - collected Ae . - pubmed
[ Pseudomonas aeruginosa meningitis in a 2 months old infant ] . - pubmed
[ Influence of moderate body weight excess on the nycthemeral pattern of blood pressure , renal function and sodium and water excretion in patients with essential hypertension ] . - pubmed
We studied the relationships between the body mass index ( BMI ) and the nycthemeral pattern of blood pressure ( BP ) , renal function and sodium and water excretion ( EX ) in a group of 25 moderately hypertensive untreated men ( 41 + /- 2 y , 80 + /- 3 kg ) . - pubmed
The selective serotonin reuptake inhibitors controversy in the treatment of depression in children . - pubmed
BACKGROUND : Reperfusion before primary PCI in patients with ST - segment elevation myocardial infarction ( STEMI ) is associated with an improved outcome . - pubmed
Hyperglycemia in patients with STEMI is associated with an adverse prognosis . - pubmed
METHODS : A total of 460 consecutive patients with STEMI treated with primary PCI were included in this analysis . - pubmed
RESULTS : Hyperglycemia was observed in 70 % and TIMI flow grade 3 before primary PCI in 17 % of the patients . - pubmed
Patients with hyperglycemia less often had TIMI flow grade 3 before primary PCI ( 12 % vs. 28 % , p & lt ; 0.001 ) . - pubmed
CONCLUSIONS : Hyperglycemia in patients with STEMI is an important predictor of impaired epicardial flow before reperfusion therapy has been initiated . - pubmed
Despite the significant decline in the incidence of acquired immune deficiency syndrome ( AIDS)-related KS with the use of highly active antiretroviral therapy ( HAART ) , some patients , even those with a good immune restoration , still have aggressive disease . - pubmed
Nine human immunodeficiency virus ( HIV )- infected patients were treated from 1997 to 2002 with docetaxel . - pubmed
Grade 4 neutropenia and thrombocytopenia were observed in four of nine and one of nine patients , respectively . - pubmed
One patient died after sepsis . - pubmed
CONCLUSIONS : Docetaxel has a good and rapid efficacy in anthracycline - pretreated patients with severe AIDS - related KS . - pubmed
Like 2 - hydroxy-1,4 - naphthoquinone , the 2 - amino - derivative was found to cause both haemolytic anaemia and renal tubular necrosis in rats . - pubmed
woesei may have acquired by lateral gene transfer more than 100 ORFs from other organisms living in the same thermophilic environment to produce the type strain of P. - pubmed
Although severe disease develops only in about 1 % of infections , WNV has claimed a total of 564 lives in the 5 years from 1999 to 2003 . - pubmed
Phylogenetic analysis of Brazilian HIV type 1 subtype D strains : tracing the origin of this subtype in Brazil . - pubmed
HIV-1 Subtype D occurs mainly in East and Central African countries , especially Uganda , where the prevalence of HIV-1 infection is among the highest in the world . - pubmed
Sequences from an Angolan immigrant showed close genetic similarity with a strain described in Finland , from an HIV patient of African origin , whereas all four autochthonous Brazilian sequences clustered with South African strains , where subtype D occurs only in isolated cases . - pubmed
Our results suggest the successful introduction and circulation in Brazil of closely related HIV-1 subtype D strains , possibly of South African origin . - pubmed
Cystic hydatic disease in sheep : treatment with percutaneous aspiration and injection with dipeptide methyl ester . - pubmed
( 4 ) Aspirin and sulindac were tested for the prevention of polyps in patients with familial adenomatous polyposis , with uncertain results and weak evidence of effectiveness . - pubmed
It involved 77 patients with familial polyposis and colorectal polyps , and 6 patients with only duodenal polyps . - pubmed
Community - acquired necrotizing fasciitis due to Pseudomonas aeruginosa . - pubmed
Furthermore , DNA - DNA hybridization showed only 54 - 66 % DNA relatedness between the novel isolates and strains of B. - pubmed
The type strain is FO-36b(T ) (= ATCC BAA-1126(T)=NBRC 100820(T ) ) . - pubmed
OBJECTIVE : To compare the appropriate screening for and the prevention and treatment of osteopenia and osteoporosis in transplant patients before and after a bone health protocol was implemented . - pubmed
The groups were well matched , with no statistically significant differences noted for any of the baseline characteristics that were compared , including the modifiable and nonmodifiable risk factors known to put a patient at increased risk for osteopenia or osteoporosis . - pubmed
Exotic fungal infection in a horse . - pubmed
Compounds 9 and 24 were also tested as gamma/(gamma+beta ) mRNA inducers in erythroblasts obtained from patients with beta(0 ) thalassemia . - pubmed
Dysfunction of endothelial cells ( EC ) is known to promote abnormal vascular growth such as that in atherosclerosis and arteriosclerosis and has been postulated as an initial trigger of the progression of atherosclerosis in patients with diabetes mellitus , and hyperglycemia is an independent risk factor for the development of cardiovascular disease . - pubmed
A recent clinical trial suggested that statins prevent several vascular events in patients with type 2 diabetes without a high concentration of LDL - cholesterol . - pubmed
These pleiotropic effects of statins can be expected to improve endothelial dysfunction through nitric oxide production and/or an anti - oxidant effect in diabetic patients . - pubmed
We compared the clinical benefits of a 12 - month exercise intervention programme consisting of either brisk walking or a medical fitness programme in type 2 diabetes patients . - pubmed
METHODS : We randomised 92 type 2 diabetes patients ( 60 + /- 9 years old ) to either three times a week of 60 min brisk walking ( n = 49 ) or medical fitness programme ( n = 43 ) . - pubmed
BACKGROUND : Human parechoviruses ( HPeVs ) have been associated with severe conditions such as neonatal sepsis and meningitis in young children . - pubmed
CONCLUSIONS : These results suggest that HPeV screening of paediatric clinical samples should be included in viral diagnostics in suspected cases of neonatal sepsis and meningitis . - pubmed
METHODS : From April 2005 to August 2006 , 26 cases ( 30 sides ) of alveolar cleft were treated with trabecular substance of self - ilium combined with the decalcified dentinal matrix of human ( DDM ) . - pubmed
RESULTS : Twenty - three patients achieved healing by first intention , oronasal fistulas were closed successfully . - pubmed
RATIONALE : Malnutrition in hospitals is often not assessed and malnourished patients rarely receive specific nutritional therapy . - pubmed
Twenty - two depressed mothers of psychiatrically ill children were recruited from a larger clinical trial ; half were randomly assigned to receive an adapted form of interpersonal psychotherapy ( IPT - MOMS ) , while the other half received treatment as usual ( TAU ) . - pubmed
The effect of subcutaneous injections of benzoquinone on Staphylococcus aureus infection of the bovine mammary gland . - pubmed
Following autologous transplant and engraftment , 30 patients ( 35.7 % ) had a transient secondary decline in their plt counts , which was not associated with graft rejection , relapse or infection . - pubmed
One patient had a previous ceramic implantation and the other a large titanium mesh , whose precedent local skin flap methods to treat the scalp ulcer were not successful . - pubmed
METHODS : Thirty - eight lesions from 37 patients with angina pectoris who demonstrated & gt;70 % coronary stenosis on multislice computed tomography were evaluated by noncontrast T1WI using a 1.5 - T magnetic resonance imager , and 25 lesions were evaluated by intravascular ultrasound . - pubmed
Noncontrast T1WI in cardiac magnetic resonance imaging may be useful for the assessment of coronary plaque characterization in patients with coronary artery disease . - pubmed
Long - term flaxseed oil supplementation diet protects BALB / c mice against Streptococcus pneumoniae infection . - pubmed
pneumoniae D39 serotype 2 infection in mice . - pubmed
Moderate pneumonia was observed in supplemented , infected mice compared to severe pneumonia seen in control mice . - pubmed
[ Vein thromboembolism prevention in stroke patients ] . - pubmed
VENOUS THROMBOEMBOLISM PREVENTION IN STROKE : The high incidence of deep vein thrombosis ( 30 % clinically and up to 50 % subclinically ) in acute stroke hemiparetic and bed ridden patients within two weeks from the onset and 1 - 2 % pulmonary embolism with the fatal outcome in the first month clinically and 17 % of all fatal outcomes in postmortem investigations present a necessity for the early venous thromboembolism prevention . - pubmed
On the other hand , the most powerful prevention strategy -- anticoagulation has important limitations in acute stroke patients : almost impossible to be used in cerebral haemorrhage and a great risk for the development of haemorrhagic transformation in cerebral infarction . - pubmed
CONCLUSION : Venous thromboembolism prevention in stroke patients is necessary because of a greater risk for venous thromboembolism in these patients according to the nature of illness and functional disability , but also a problem because of limited possibility to recommend the proper medicament according to the risk of serious complications . - pubmed
The necessity of preventing venous thromboembolism and estimation of effectivity - risk ratio in stroke patients , beside plenty of studies and consensus conferences , remain individual and often very difficult . - pubmed
As the result of improved bacteriological techniques , Kingella kingae is a slow - growing Gram - negative coccobacillus that is emerging as an important cause of spondylodiscitis in children younger than 3 years of age . - pubmed
A 64 - year - old woman presented with right hip pain of 6 years ' duration , accompanied by limping of 1 years ' duration . - pubmed
Therefore , caution should be taken with administration of anticoagulant therapy in patients with massive hemorrhage , especially in patients with continuous low blood pressure . - pubmed
A gram - positive and aerobic bacterium , designated strain YIM 49065 ( T ) , was isolated from rhizospheric soil of Jatropha curcas in Yunnan , China . - pubmed
Furthermore , DNA - DNA hybridizations among strains YIM 49065 ( T ) , I. - pubmed
, for strain YIM 49065 ( T ) ( = DSM 23217(T ) = CCTCC AA 209077(T ) ) . - pubmed
Lymphocytic choriomeningitis virus ( LCMV ) is a rare cause of central nervous system disease in humans . - pubmed
ATP - Sensitive Potassium Channel - Deficient Mice Show Hyperphagia but Are Resistant to Obesity . - pubmed
Baccharis trimera is a plant popularly used as a tea and to treat gastrointestinal diseases and inflammatory processes as well . - pubmed
Coronary artery disease in elderly women : a disturbed relation of estrogen with testosterone . - pubmed
A pattern of high phagocytosis , consumption of classical pathway components , and a broad anti - H ab repertoire was seen particularly in patients with nephritis and serositis . - pubmed
Management of factor VII - deficient patients undergoing joint surgeries -- preliminary results of locally developed treatment regimen . - pubmed
Preliminary results demonstrate that rFVIIa administered according to our treatment regimen is an effective and safe haemostatic agent for hypoproconvertinaemia patients undergoing orthopaedic surgery . - pubmed
: METHODS : A multicenter , consecutive case series of patients with biopsy - proven conjunctival , orbit , eyelid , or lacrimal gland / sac lymphoma was performed . - pubmed
The effects of different dobutamine infusion rates on hypercapnic depression of diaphragmatic contractility in pentobarbital - anesthetized dogs . - pubmed
A tissue array was constructed comprising 63 EOC patients . - pubmed
Type 2 diabetes was induced in overnight fasted Sprague Dawley rats pre - treated with nicotinamide ( 100 mg / kg , i.p . ) - pubmed
The rats were divided into ; I - nondiabetic , II - diabetic control , III - sitagliptin ( 5 mg / kg , p.o . ) - pubmed
A single - dose extended - toxicity study for NOTA-2Rs15d was performed on healthy mice up to a dose of 10 mg / kg . - pubmed
An analysis of cervical spine magnetic resonance imaging findings after normal computed tomographic imaging findings in pediatric trauma patients : ten - year experience of a level I pediatric trauma center . - pubmed
BACKGROUND : A variety of radiologic screening protocols exist for evaluation of pediatric trauma patients with potential cervical spine ( c - spine ) injuries . - pubmed
METHODS : A retrospective chart review of trauma patients evaluated at Rady Children 's Hospital , San Diego , between January 2000 and February 2010 was conducted . - pubmed
Trauma patients who were younger than 18 years , placed in c - spine precautions , had a normal c - spine CT scan , who subsequently had a c - spine MRI were included . - pubmed
CONCLUSION : Our results suggest that high - resolution CT scan with sagittal and coronal reconstructions may be comparable with MRI for the detection of unstable c - spine injuries in pediatric trauma patients . - pubmed
Autologous rabbit adipose tissue - derived mesenchymal stromal cells for the treatment of bone injuries with distraction osteogenesis . - pubmed
METHODS : Bone defects were produced in the tibias of New Zealand rabbits that had previously undergone adipose tissue extraction . - pubmed
MATERIAL AND METHODS : Histology in 53 IgAN patients ( M / F 35/18 age 40.5 years ( 17 - 65 ) ) was evaluated using the Oxford classification system . - pubmed
We report a series of 14 patients with multiple myeloma or NHL successfully mobilized and harvested by plerixafor together with large - volume leukaphereses ( LVL ) . - pubmed
The failure of nonleukopenic doses of colchicine to suppress urate crystal - induced canine joint inflammation . - pubmed
Colchicine suppressed the development of urate crystal - induced canine synovitis only at a dose ( 0.25 mg / kg ) that produced a peripheral leukopenia ; half that amount produced neither leukopenia nor inhibition of the inflammatory response . - pubmed
The canine model differs from human gouty inflammation and from urate crystal - induced human inflammation , both of which processes respond to small , nonleukopenic doses of colchicine . - pubmed
In patients with suspected IgG4 - RD and skin changes , skin biopsy may serve as a diagnostic screen or to supplement nondiagnostic visceral biopsy specimens . - pubmed
MATERIALS AND METHODS : A total of 20 enamel samples of human molar teeth were subjected to artificial caries lesion formation using pH cycling method and was verified using high resolution scanning electron microscope ( HRSEM ) . - pubmed
Carvedilol ameliorates early diabetic nephropathy in streptozotocin - induced diabetic rats . - pubmed
The aim of this study therefore is to evaluate the possible protective effect of carvedilol on streptozotocin - induced early diabetic nephropathy and various mechanisms underlie this effect in rats . - pubmed
injection of streptozotocin ( 65 mg / kg ) was administered to induce early diabetic nephropathy in Wistar rats . - pubmed
In conclusion , carvedilol protects rats against streptozotocin - induced early diabetic nephropathy possibly , in part , through its antioxidant as well as anti - inflammatory activities , and ameliorating podocyte injury . - pubmed
The cardiovascular autonomic imbalance in patients after myocardial infarction ( MI ) provides a significant increase in mortality rate , and seems to precede metabolic , hormonal , and immunological changes . - pubmed
Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases . - pubmed
Using expression profiles from postmortem prefrontal cortex samples of 624 dementia patients and non - demented controls , we investigated global disruptions in the co - regulation of genes in two neurodegenerative diseases , late - onset Alzheimer ' s disease ( AD ) and Huntington ' s disease ( HD ) . - pubmed
We identified networks of differentially co - expressed ( DC ) gene pairs that either gained or lost correlation in disease cases relative to the control group , with the former dominant for both AD and HD and both patterns replicating in independent human cohorts of AD and aging . - pubmed
CONCLUSIONS : Patients supported with extracorporeal membrane oxygenation were exposed to large RBC transfusion volumes for treatment of mild anemia resulting from blood loss , particularly phlebotomy . - pubmed
Within the light of recent WHO recommendations for Bacillus thuringiensis israelensis ( Bti ) use against malaria and other vector species , larval source management could see a revival in the upcoming years . - pubmed
We postulated that human inter - seizure intervals would follow a power - law relationship , and furthermore that evidence for the existence of a long - memory process could be established in this relationship . - pubmed
Our results provide evidence that companion animals like dogs may be MRS carriers , and that continued surveillance of MRS in companion animals is required to prevent increased incidences in humans . - pubmed
An internal inclusivity validation demonstrated detection of all 50 tested strains of . - pubmed
1,4 - BQ demonstrated concentration - dependent cytotoxicity in mouse BM cells . - pubmed
Taken together , 1,4 - BQ caused lineage - related cytotoxicity in mouse HPCs , demonstrating greater toxicity in single - lineage progenitors than in those of multi - lineage . - pubmed
Diffusion in the corpus callosum in patients with early schizophrenia . - pubmed
Diffusion in the cerebral corpus callosum in patients with early schizophrenia was studied by diffusion tensor MRT and magnetic resonance spectroscopy . - pubmed
Further research is needed to discern clear mechanisms and to help efforts to counteract muscle weakness and exercise intolerance in uremic patients . - pubmed
Chryseobacterium indologenes in four patients with leukemia . - pubmed
Chryseobacterium indologenes is a rare opportunistic pathogen causing hospital - acquired infection . - pubmed
Two of the patients , undergoing peripheral blood allogeneic hematopoietic stem cell transplantation ( alloHSCT ) from human leukocyte antigen - identical sibling donors , died of pneumonia caused by C. - pubmed
Blood infection with C. - pubmed
CONCLUSION : The quality of care for febrile neutropenia in patients presenting through the ED was comparable to those directly admitted to the hospital in this 2 - center study . - pubmed
The effects of DL-3 - n - butylphthalide in patients with vascular cognitive impairment without dementia caused by subcortical ischemic small vessel disease : A multicentre , randomized , double - blind , placebo - controlled trial . - pubmed
METHODS : In this randomized , double - blind , placebo - controlled trial , we enrolled patients aged 50 - 70 years who had a diagnosis of subcortical Vascular cognitive impairment without dementia at 15 academic medical centers in China . - pubmed
DISCUSSION : Over the 6 - month treatment period , NBP was effective for improving cognitive and global functioning in patients with subcortical vascular cognitive impairment without dementia and exhibited good safety . - pubmed
CONCLUSIONS : Since massive transfusion provokes further problems in patients who are already severely traumatized and anaemic , once this course of action has been decided upon , a profound knowledge of its potential complications , careful monitoring and proper follow - up are all essential . - pubmed
The antiproliferative activity of two chito - specific agglutinins purified from Benincasa hispida ( BhL ) and Datura innoxia ( DiL9 ) of different plant family origin was investigated on various cancer cell lines . - pubmed
PURPOSE : To evaluate differences in measurements of macular pigment optical density ( MPOD ) in patients with dry age - related macular degeneration ( AMD ) and a group of healthy patients ( control group ) . - pubmed
METHODS : This cross - sectional study included 31 eyes from 31 patients with bilateral dry AMD , 21 eyes from 21 cases with dry AMD in the study eye and exudative AMD in the fellow eye . - pubmed
A randomised , double - blinded , placebo - controlled clinical study on intra - articular hyaluronan treatment in equine lameness originating from the metacarpophalangeal joint . - pubmed
BACKGROUND : Intra - articular inflammation resulting in lameness is a common health problem in horses . - pubmed
Exogenous intra - articular hyaluronic acid has been shown to provide an analgesic effect and reduce pain in equine and human osteoarthritis . - pubmed
High molecular weight non - animal stabilized hyaluronic acid ( NASHA ) has gained popularity in the treatment of human arthritic conditions due to its long - acting pain - relieving effects . - pubmed
The aim of this study was to compare the response to treatment of lameness localized in the equine metacarpophalangeal joint injected with non - animal stabilized hyaluronic acid ( NASHA ) and placebo ( saline ) . - pubmed
CONCLUSIONS : In the present study , a single IA NASHA injection was not better than a single saline injection for reducing lameness in horses with synovitis or mild osteoarthritis . - pubmed
On - going research is attempting to use amphibian symbiotic bacteria to develop probiotic treatments that can protect hosts from the causative agent of chytridiomycosis , the fungal pathogen Batrachochytrium dendrobatidis . - pubmed
Giraffe skin disease ( GSD ) is a disorder of undetermined etiology that causes lesions on the forelimbs of Masai giraffe ( Giraffa camelopardalis tippelskirchi ) . - pubmed
AIMS : Hip resurfacing arthroplasty ( HRA ) is an alternative to conventional total hip arthroplasty for patients with osteonecrosis ( ON ) of the femoral head . - pubmed
PATIENTS AND METHODS : Long - term survivorship , clinical scores and radiographic results for 82 patients ( 99 hips ) treated with HRA for ON over a period of 18 years were reviewed retrospectively . - pubmed
Patients were resurfaced regardless of the size of the osteonecrotic lesion . - pubmed
Erlotinib has comparable clinical efficacy to chemotherapy in pretreated patients with advanced non - small cell lung cancer ( NSCLC ): A propensity - adjusted , outcomes research - based study . - pubmed
MATERIALS AND METHODS : We included patients with advanced NSCLC receiving at least two lines of palliative systemic treatment between January 2005 and December 2014 and not harbouring targetable driver mutations . - pubmed
CONCLUSION : The present study suggests erlotinib to have similar clinical efficacy compared to chemotherapy in patients with pretreated advanced NSCLC and no known molecular targetable alterations . - pubmed
Burkholderia pseudomallei , the causative agent of a fatal disease melioidosis , is one such biothreat agent whose differentiation from its near - neighbor species is always a challenge . - pubmed
OBJECTIVE : Exposure to maternal depression across the first years of life markedly increases children 's susceptibility to psychopathology , yet no study has tested its effects on the maturation of children 's social brain . - pubmed
Children of mothers with depression showed enhanced alpha rebound to pain in the right posterior superior temporal gyrus , which was unrelated to emotion detection abilities , pointing to decreased late processing of others ' overwhelming experiences in socio - cognitive areas . - pubmed
CONCLUSION : These findings , from the first study to examine maternal depression and early caregiving as long - term predictors of children 's neural empathic response , pinpoint a decrease in top - down socio - cognitive mechanisms as potential pathways for the cross - generational transfer of vulnerability from mothers with depression to their offspring and highlight the need for early interventions focused on enhancing maternal attunement . - pubmed
Unlike most other lesions in patients with unstable symptoms , where coronary intervention with stenting is recommended , patients with SCAD generally fare better with conservative measures than with intervention , unless there is hemodynamic instability . - pubmed
METHODS : Twenty - three LV tissue samples were obtained from ICM patients ( n=13 ) undergoing heart transplantation and control donors ( n=10 ) for RNA sequencing analysis . - pubmed
Patients can be at risk of angle - closure glaucoma in this condition , and traditional methods of angle assessment can be subjective and difficult to perform in the inflamed eye . - pubmed
OBJECTIVE : Obesity variably disrupts human health , but molecular - based patients ' health - risk stratification is limited . - pubmed
Adipose tissue ( AT ) stresses may link obesity with metabolic dysfunction , but how they signal in humans remains poorly - characterized . - pubmed
MATERIALS AND METHODS : The data of 186 patients aged & gt;80 years with colorectal cancer were collected from a computer database , and the variables were analyzed by both uni- and multivariate analyses . - pubmed
CONCLUSIONS : After good surgical selection , low early mortality and acceptable long - term survival can be achieved even in the oldest old patients with colorectal cancer . - pubmed
The first case was an 11 - month - old boy presenting with complaints of recurrent soft tissue infection , ear infection , anemia , and thrombocytopenia with a low platelet volume . - pubmed
MATERIALS AND METHODS : Seventeen term neonates with moderate or severe HIE underwent therapeutic hypothermia . - pubmed
Updates on early peanut introduction and prevention of peanut allergy . - pubmed
We found many patients with LA and processed them appropriately . - pubmed
RESULTS : The wound of all patients healed up . - pubmed
Prospective Evaluation of Predictors of Testis Atrophy After Surgery for Testis Torsion in Children . - pubmed
METHODS : Patients 2 months-18 years old with unilateral acute scrotum were consecutively enrolled in a National Institutes of Health transcutaneous near - infrared spectroscopy study , with a subgroup analysis of the true torsion group . - pubmed
All patients with a black or hemorrhagic testis had & gt;80 % volume loss . - pubmed
Simulated Microgravity Culture Enhances the Neuroprotective Effects of Human Cranial Bone - Derived Mesenchymal Stem Cells in Traumatic Brain Injury . - pubmed
In this study , we investigated the therapeutic mechanisms of transplantation of cMSCs cultured under MG conditions in traumatic brain injury ( TBI ) model mice . - pubmed
We found that the cyp17a1 - deficient fish at 3 months postfertilization ( mpf ) were all fertile males with normal testis and spermatogenesis but compromised male - typical mating behaviors and secondary sex characters ( SSCs ) , including breeding tubercles , body pigmentation , and anal fin coloration . - pubmed
This all - male phenotype of the cyp17a1 - deficient fish could be restored with testosterone or estradiol treatment . - pubmed
Arboviruses incorporate a vast collection of genetically diverse viral pathogens including that of dengue , Zika and chikungunya . - pubmed
Case Report : A 22 - year - old gentleman presented with ASIA Aparaplegia following road traffic accident . - pubmed
The patient also had liver laceration . - pubmed
The toxicity of alphadelta - BgTx-1 ( LD50 = 0.17 - 0.28 microg / g mouse , i.p . - pubmed
Tai chi chuan exercises improve functional outcomes and quality of life in patients with primary total knee arthroplasty due to knee osteoarthritis . - pubmed
A single - centre , single - blind , randomised controlled trial was designed to explore whether tai chi chuan ( TCC ) exercises can improve the functional outcomes and the quality of life ( QOL ) in patients with primary TKA due to knee osteoarthritis ( OA ) . - pubmed
MATERIALS AND METHODS : One hundred seven participants with primary TKA for end - stage knee OA were enrolled from January 2014 to January 2017 . - pubmed
This study aimed to explore ocular Demodex infestation on the microstructure changes of the meibomian glands ( MGs ) in patients with MGD by in vivo confocal microscopy ( IVCM).We retrospectively reviewed 103 eyes of 52 patients with MGD and 62 eyes of 31 non - MGD patients . - pubmed
Worldwide , over 6 million people are infected with Trypanosoma cruzi , the pathogen that causes Chagas disease ( CD ) . - pubmed
We described a 55 - year - old man , in whom the first manifestation of retroperitoneal fibrosis ( RPF ) was only coronary arterial involvement , which had no periaortic or peri - iliac and urinary system retroperitoneum involvement in general and other systemic clinical manifestations . - pubmed
Hepatitis C virus ( HCV ) is common among people living with human immunodeficiency virus ( PLWH ) . - pubmed
Extrahepatic manifestations of HCV , including myocardial infarction ( MI ) , are a topic of active research . - pubmed
We examined the association between HCV and MI in the Centers for Acquired Immunodeficiency Syndrome Research Network of Integrated Clinical Systems , a multi - center clinical cohort of PLWH . - pubmed
We estimated the association between chronic HCV ( RNA+ ) and time to MI adjusting for demographic characteristics , cardiovascular risk factors , clinical characteristics and history of injecting drug use . - pubmed
HCV was associated with a 46 % greater risk of T2MI ( adjusted hazard ratio ( aHR ) 1.46 , 95 % CI : 1.09 , 1.97 ) but not T1MI ( aHR 0.87 , 95 % CI : 0.58 , 1.29 ) . - pubmed
In an exploratory cause - specific analysis of T2MI , HCV was associated with a 2 - fold greater risk of T2MI attributed to sepsis ( aHR 2.01 , 95 % CI : 1.25 , 3.24 ) . - pubmed
We compared the recurrence - free survival ( RFS ) associated with CF plus Adriamycin ( ACF ) with that associated with CF plus docetaxel ( DCF ) to select an alternative regimen in a new phase III trial investigating the optimal neoadjuvant treatment of patients with ESCC . - pubmed
PATIENTS AND METHODS : Patients with resectable advanced ESCC were randomly assigned to either ACF ( Adriamycin 35 mg / m2 , cisplatin 70 mg / m2 i.v . - pubmed
CONCLUSION : Compared with ACF , DCF chemotherapy was associated with prolonged RFS for patients with resectable advanced ESCC . - pubmed
Methods : Since coronary artery bypass surgery ( CABG ) represents a reversible ischemia - reperfusion sequence , we assessed if statin reload is effective in patients undergoing off - pump CABG ( n = 100 ) in limiting myocardial injury . - pubmed
CONCLUSION : miR-29b potentiates TMZ sensitivity against GBM cells by inducing autophagy and the combined use of miR-29 mimic and TMZ might represent a potential therapeutic strategy for GBM patients . - pubmed
Combined Mesenchymal Stromal Cell Therapy and ECMO in ARDS : A Controlled Experimental Study in Sheep . - pubmed
METHODS : ARDS was induced in 14 sheep , after which they were established on veno - venous ECMO . - pubmed
In male Wistar rats , systemic inflammation was induced by a tail vein injection of lipopolysaccharides ( LPS challenge ; 12 mg / kg ) . - pubmed
Patients with type 2 diabetes exhibit higher cardiovascular risk than normal individuals . - pubmed
Optimal blood glucose levels are rarely achieved in diabetic patients . - pubmed
CONCLUSION : Analysis of CMT for patients with early - stage HL demonstrates variability in RT dose , including increasing use of 20 Gy and decreasing use of high doses > 36 Gy . - pubmed
[ Correlation analysis of the prognostic value of serum hyaluronic acid for breast cancer patients ] . - pubmed
Objective : To explore the correlation between preoperative serum hyaluronic acid ( HA ) level and prognosis of breast cancer patients . - pubmed
Methods : The 98 patients with breast cancer who underwent surgical treatment in the Oncology Department of Sir Run Run Shaw Hospital , Zhejiang University School of Medicine from January 2004 to November 2014 in a historical cohort were included , aged ( 52.5 + -9.4 ) years . - pubmed
OBJECTIVE : This study aimed to compare the diagnostic performance of cardiac biomarkers and to evaluate the optimal cut - off values for echocardiographic cardiac injury prediction in patients with carbon monoxide ( CO ) poisoning . - pubmed
METHODS : This retrospective observational cohort study included adult patients with acute CO poisoning . - pubmed
Patients who did not undergo transthoracic echocardiography , which was used to define patients with cardiac injury ( ejection fraction < 55 % ) , were excluded . - pubmed
Fifteen ( 13.2 % ) patients had cardiac injury . - pubmed
Aim To identify new predictors for vulnerability of atherosclerotic coronary plaques in patients with stable ischemic heart disease ( sIHD).Material and methods This prospective , single - center study included 58 patients with sIHD . - pubmed
On a set of pilot data , accuracy of bradykinesia prediction is comparable to that recorded by blinded human experts . - pubmed
Mapping the Alterations of Glutamate Using Glu - Weighted CEST MRI in a Rat Model of Fatigue . - pubmed
The purpose of this study is to map the alternations of brain glutamate in a rat model of fatigue . - pubmed
Methods : Rats were subjected to 10 days fatigue loading procedure ( fatigue group ) or reared without any fatigue loading ( control group ) . - pubmed
Spontaneous activities of rats in the fatigue group were recorded from 3 days before fatigue loading to 4 days after the end of fatigue loading . - pubmed
Results : Rats in the fatigue group exhibited significant reduced spontaneous activities after 10 - day fatigue loading . - pubmed
In the entire cohort , the transection line was changed in 2 patients , resulting in no AL . - pubmed
Nevertheless , AL still developed in 6 patients ( 5.4 % ) , 5 of whom were in the MF group , and delayed TAP was found in 5 of 6 patients . - pubmed
External validation of two predictive models for postoperative fever after retrograde intrarenal surgery ( RIRS ) in pediatric patients . - pubmed
OBJECTIVE : The aim of this study is to validate the efficacy and reliability of two predictive models for postoperative fever after retrograde intrarenal surgery ( RIRS ) in pediatric patients Materials and Methods : A total of 124 children who were treated with RIRS between August 2014 and August 2020 in our center were included . - pubmed
Eventually , 21 children ( 16.9 % ) were suffered from postoperative fever . - pubmed
21 pediatric patients ( 16.9 % ) were suffered from postoperative fever . - pubmed
Nomogram 1 presented with better predictive power for postoperative fever after RIRS in pediatric patients . - pubmed
A series of patients with congenital blood and lymph anomalies of the lower limb investigated and treated at St Thomas 's Hospital , London , are reviewed . - pubmed
Patients in the arteriovenous shunt group had large hyperplastic lymph pathways , which were possibly either congenital or a hypertrophic response . - pubmed
There were 5 deaths in the series , 4 of these being in the scattered angioma group and in patients in whom the deformities extended beyond the limb into the trunk . - pubmed
In 13 patients with hypertension and renal artery stenosis the stenosis was dilated by an intra - arterial balloon catheter under local anaesthesia . - pubmed
Dilatation of renal artery stenosis by an intra - arterial balloon catheter is a promising treatment for patients with hypertension and renal artery stenosis . - pubmed
Circulatory effects of magnesium sulfate in normotensive and renal hypertensive pregnant sheep . - pubmed
We have studied the effects of magnesium sulfate ( MgSO4 ) administration in chronically instrumented normotensive and hypertensive pregnant sheep . - pubmed
Animals of 90 to 144 days ' gestation were divided in two groups ; those with normotensive arterial pressure and those in which renovascular hypertension had been produced . - pubmed
Because MgSO4 produced no significant hemodynamic changes , we feel that : ( 1 ) its use in obstetrics must be based on its anticonvulsant action and ( 2 ) MgSO4 in either normotensive or hypertensive patients is not associated with impairment of uteroplacental blood flow . - pubmed
During one six - month period 11 patients were referred with a diagnosis of coronary artery disease , because of recurrent episodes of severe , prolonged retrosternal chest pain necessitating from one to seven hospital admissions per patient for " suspect myocardial infarction " . - pubmed
Selective coronary arteriograms were normal in 10 patients and revealed nonobstructive coronary artery disease in the 11th patient . - pubmed
Hypertrophy of rat extensor digitorum longus muscle injected with bupivacaine . - pubmed
Enterotoxin producing strains of E. - pubmed
Rarely giardia lamblia , entamoeba histolytica and cryptosporidia are causative organisms . - pubmed
for 5 days we were able to demonstrate a significant clinical and bacteriologic effect in 132 patients with salmonellosis and campylobacteriosis . - pubmed
Patients who were treated with the drug included 2 with complicated urinary tract infections ( UTI ) , 29 with chronic prostatitis and 3 with chronic non - chlamydial epididymitis . - pubmed
In 2 cases of chronic UTI , infected by P. - pubmed
For evaluating the effectiveness on chronic prostatitis , the patients were divided into 2 groups ; group I ( G - I ) was chronic bacterial ( number of isolates including GNR or E. - pubmed
Two murine models of polycystic kidney disease ( PKD ) in humans are currently available : the infant - type cpk in mice and the adult - type pcy mutation in mice . - pubmed
Our linkage analysis was to determine whether these genes are allelic forms of the same gene , or infant - type and adult - type PKD resulting from homozygous and heterozygous mutation , as in the rat Cy gene . - pubmed
Over - expression of an endogenous milk protein gene in transgenic mice is associated with impaired mammary alveolar development and a milchlos phenotype . - pubmed
Cardioversion was achieved in 70 % of patients with atrial fibrillation and in 96 % of patients with atrial flutter . - pubmed
[ The effect of exercise on blood gases and oxygen transport in patients with chronic obstructive pulmonary disease ] . - pubmed
The effect of exercise on pulmonary gas exchange and oxygen transport was studied in 42 patients with COPD . - pubmed
Our data imply that PO2 changes of COPD patients during exercise may be related to the patient 's ventilation , pulmonary gas exchange and mixed venous PO2 levels . - pubmed
Sixty - four traumatically brain injured patients were divided into three groups . - pubmed
A 43 - year - old man had severe upper abdominal pain and weight loss of 8 kg for over three months . - pubmed
Long - term effect of ipratropium bromide and fenoterol on the bronchial hyperresponsiveness to histamine in children with asthma . - pubmed
We studied the effects of the anticholinergic ipratropium bromide ( 40 micrograms three times daily ) and the beta - agonist , fenoterol ( 0.2 mg three times daily ) , both administered by powder inhaler , on bronchial hyperresponsiveness ( BHR ) to histamine in children , aged 7 to 15 years with mild stable asthma and limited bronchoconstriction who had a highly increased BHR . - pubmed
We concluded that long - term treatment with ipratropium bromide or fenoterol had no effect on BHR in children with mild stable asthma . - pubmed
Subclass specificity of antibodies were studied in sera of 108 patients suffering from pollinosis . - pubmed
Antibodies of this isotype were found in the majority of patients with tree pollen allergy but not in patients with grass pollen allergy . - pubmed
In case of hepatitis further investigations were performed for heterophilic infectious mononucleosis antibodies and for hepatitis B virus DNA . - pubmed
Somatostatin inhibits the ventilatory response to hypoxia in humans . - pubmed
Ten strains of adenovirus representing 10 serotypes were administered intratracheally to 3 - week - old specific - pathogen - free chickens , which also received 2.5 X 10(5 ) colony - forming units of a pathogenic Escherichia coli intranasally . - pubmed
A prospective randomized trial was performed in 44 patients undergoing elective coronary artery bypass grafting to assess the effects of the membrane oxygenator and dipyridamole on platelet counts , platelet activation products , and postoperative bleeding . - pubmed
Patients who were randomized to receive a bubble oxygenator and no dipyridamole had the lowest postoperative platelet counts , the greatest blood loss , and the most blood products transfused . - pubmed
Platelet counts were highest and blood loss was least in patients randomized to receive a membrane oxygenator and dipyridamole ( p less than .05 ) . - pubmed
[ Initial clinical experience using an interdisciplinary management concept for pregnant patients with liver damage ] . - pubmed
Twenty patients with metastatic colon cancer without prior chemotherapy received 2 g / m2 of 5 - fluorouracil ( 5 - FU ) infused over 24 h for 5 days preceded by allopurinol 900 mg orally for 1 week and then continued during , and for 1 week after the infusion was completed . - pubmed
Fourteen patients were evaluable for both response and toxicity . - pubmed
No significant hematologic toxicity was seen but 18 of 19 patients evaluable for toxicity developed mucositis resulting in dose reductions in 3 patients and refusal of a second course by 2 additional patients . - pubmed
The epidemiology of diabetes in mammals ( with comments in detail on the Tongaat Sugar Survey Company ) . - pubmed
[ Hepatography in assessing liver function in patients with circulatory insufficiency ] . - pubmed
Studies of mammary carcinoma metastasis in a mouse model system . - pubmed
The biological and metastatic properties of cells from a murine mammary adenocarcinoma , MT1 , were studied during serial transplantation in syngeneic hosts . - pubmed
Immune complexes in human malignant tumours . - pubmed
High levels of immune complexes have been detected in the serum of patients with malignant solid tumours , leukemias and lymphomas . - pubmed
Prophylactic antibiotics were given to a group of 389 orthognathic surgery patients , with the development of 1 case of acute and 12 cases of chronic infection . - pubmed
One case of chronic infection appeared in another group of 76 patients who had not received prophylactic antibiotics . - pubmed
The authors present the radiotherapeutic results achieved in 56 patients with endocrine ophthalmopathy , 15 out of them with severe , so - called malignant course . - pubmed
The respiratory muscles and neurons activity in the transitional process from rhythmic respiration to its cessation and reappearance of the usual rhythmic breathing after the apnea was registered in the acute experiments on the anesthetized cats and rabbits under the action of extra intrapulmonary oxygen pressure or intravenous injection of sodium cyanide . - pubmed
Differential effect of nerve injury at birth on the activity pattern of reinnervated slow and fast muscles of the rat . - pubmed
Total blindness developed in an adult Melanesian man 36 hours after he drank 100 mL of 100 % methanol . - pubmed
In the large - scale Evaluation of c7E3 for the Prevention of Ischemic Complications ( EPIC ) trial that involved high - risk patients undergoing coronary intervention procedures , a monoclonal antibody Fab fragment ( c7E3 ) directed against this receptor , administered as a bolus and and through infusion , significantly reduced the 30 - day incidence of major ischemic events relative to placebo . - pubmed
Of 38 patients who underwent surgery since 1984 , 34 had low rectal cancer and four carcinoid or large villous adenoma . - pubmed
Four patients developed local recurrence during a median observation period of 3 years . - pubmed
Cytotoxic effects are demonstrated against human leukemia and melanoma cell lines proliferating in tissue culture and against xenografts of human breast cancer and sarcoma growing in nude mice . - pubmed
Pharmacological interference with tissue hypercatabolism in tumour - bearing rats . - pubmed
We also discuss the probable aetiology of the strokes and whether cardiac echocardiography should be performed in these patients . - pubmed
METHODS : Spleen cells from mice immunized with prostatic epithelial cells prepared from benign prostatic hyperplasia tissue were fused with myeloma cells X63Ag8 - 653 . - pubmed
To examine the influence of chronic hyperglycemia , rats were subjected to 90 % partial pancreatectomy ( Px ) , which produced glucose levels of 10.9 - 20.8 mM. - pubmed
Twenty - two patients with hyperthyroidism were included in a prospective , randomized and placebo controlled study . - pubmed
Diltiazem can be used in patients with hyperthyroidism to alleviate adrenergic manifestations . - pubmed
A solitary Peutz - Jeghers - type polyp of the rectum in a 64 - year - old Japanese man is reported . - pubmed
Weanling rats exposed to maternal low - protein diets during discrete periods of gestation exhibit differing severity of hypertension . - pubmed
In the rat , hypertension is induced by fetal exposure to maternal low - protein diets . - pubmed
Hypertension was observed in rats exposed to low protein during the following gestational periods : days 0 - 7 , days 8 - 14 and days 15 - 22 . - pubmed
Fetal exposure to maternal low - protein diets for any period in gestation may programme hypertension in the rat . - pubmed
Following in vitro lipofection transfection of the rat glioma cell line A15A5 with the plasmid transgene CMV / HyTK , which confirms hygromycin resistance and ganciclovir sensitivity , a series of experiments was planned in which the " bystander " phenomenon would be evaluated using the rodent implantation glioma model . - pubmed
However examination of the brain of rodents in which the A15A5HyTK cells were implanted showed no evidence of glioma growth . - pubmed
Furthermore , rodents having intracerebral implantation of ( i ) wild A15A5 and A15A5HyTK cells in a 50/50 mix , ( ii ) wild A15A5 and A15A5HyTK cells in a 90/10 mixture and ( iii ) wild C6 and A15A5HyTK cells in a 50/50 mix all failed to grow macroscopic tumours by 15 - 17 days irrespective of whether the animals had been administered ganciclovir ( GCV ) in the week before sacrifice . - pubmed
The implications of this study for gene therapy of human malignant glioma are discussed . - pubmed
In spite of this superiority , the long - term outcome for most patients with relapsed or refractory NHL remains unfavorable . - pubmed
Cholesterol - lowering therapy in women and elderly patients with myocardial infarction or angina pectoris : findings from the Scandinavian Simvastatin Survival Study ( 4S ) BACKGROUND : The Scandinavian Simvastatin Survival Study ( 4S ) demonstrated pronounced reductions in mortality and major coronary events in a cohort of patients with established coronary heart disease ( CHD ) . - pubmed
METHODS AND RESULTS : The 4S cohort of 4444 CHD patients included 827 women and 1021 patients & gt ; or = 65 years of age . - pubmed
In patients & gt ; or = 65 years of age in the simvastatin group , relative risks ( 95 % confidence intervals ) for clinical events were as follows : all - cause mortality , 0.66 ( 0.48 to 0.90 ) ; CHD mortality , 0.57 ( 0.39 to 0.83 ) ; major coronary events , 0.66 ( 0.52 to 0.84 ) ; any atherosclerosis - related event , 0.67 ( 0.56 to 0.81 ) ; and revascularization procedures , 0.59 ( 0.41 to 0.84 ) . - pubmed
In cultured rat alveolar epithelial cells ( RAEC ) Exo A caused cytotoxicity as measured by 51Cr release from these cells . - pubmed
Four patients ages 40 - 65 y ( mean : 53.75 + /- 10.59 ) , three with mesenteric thrombosis , and one with Crohn ' s disease were studied . - pubmed
The effects of tacrolimus ointment on immediate , late and delayed - type cutaneous allergic reactions and normal skin thickness were investigated in mice and compared with those of steroid ointments . - pubmed
After retrovirus - mediated gene transfer of a suppressor gene an increase of tumor cell apoptosis was observed . - pubmed
We have previously shown that polymorphonuclear leucocytes ( PMN ) harvested from children with cancer and exposed to chemotherapy exhibit defective bactericidal activities against both Gram - positive and Gram - negative microorganisms as well as accelerated apoptosis . - pubmed
PATIENTS : All CAPD patients who developed bacterial or culture - negative peritonitis beyond 28 days of a previous episode and without evidence of septicemia , associated tunnel infection , or known sensitivity to trial medications were accepted into the clinical trial . - pubmed
Risk assessment of bovine spongiform encephalopathy transmission through bone graft material derived from bovine bone used for dental applications . - pubmed
The recent incidents of bovine spongiform encephalopathies ( BSE ) in humans have underscored this likelihood . - pubmed
RESULTS : Results from the analyses conducted using both models showed that the risk of disease ( BSE ) transmission from BGS was negligible and could be attributed to the stringent protocols followed in sourcing and processing of the raw bovine bone used in the commercial product . - pubmed
The purpose of this study was to determine the effect of treatment with donepezil 5 mg qd on cognitive evoked potentials ( EPs ) of patients with AD . - pubmed
Patients who have had their jaws irradiated as part of management of head and neck malignancy are at risk of osteoradionecrosis ( ORN ) following tooth extraction . - pubmed
Seven patients who did not have HBO and one who did ( 15 per cent ) developed ORN . - pubmed
Ara - C , another antineoplastic agent commonly used in haematologic malignancies , induced both apoptosis and iron depletion in human acute myeloid leukaemic cells . - pubmed
Following toxicity , the dogs received either digoxin ( 0.018 mg / kg ) ( DIG ) ( n = 8) or saline ( No - DIG ) ( n = 8) . - pubmed
Animal weight , does of VER administered during the toxicity phase , and baseline values were included as covariates . - pubmed
To investigate whether the degree of splenomegaly correlates with the degree of immune stimulation , whether prophylaxis or recent treatment play a role , and whether short therapy alone is effective , we examined retrospectively the medical records of expatriates with exposure to P. - pubmed
A virus closely related to cherry green ring mottle virus ( CGRMV ) was isolated from a tree displaying typical symptoms of cherry necrotic rusty mottle disease . - pubmed
Adjuvant chemotherapy after resection of hepatocellular carcinoma causes deterioration of long - term prognosis in cirrhotic patients : metaanalysis of three randomized controlled trials . - pubmed
BACKGROUND : The goal of the current study was use metaanalysis to evaluate the effect of postoperative adjuvant chemotherapy after resection of hepatocellular carcinoma ( HCC ) , especially in cirrhotic patients . - pubmed
METHODS : One hundred - eight patients with radical resection of HCC were included in 1 of 3 prospective randomized control studies that used different postoperative chemotherapy protocols . - pubmed
Postoperative chemotherapy using the current protocols failed to improve patient outcome in all patients and failed to improve disease - free and overall survival in any patients who were included in individual protocols . - pubmed
In patients with cirrhosis , postoperative chemotherapy was associated with significantly worse disease - free ( P = 0.0376 ) and overall survival rates ( P = 0.0077 ) . - pubmed
CONCLUSIONS : The current study indicated that cancer recurrence in the remnant liver is enhanced and the long - term outcome is deteriorated by postoperative chemotherapy after resection of HCC in cirrhotic patients . - pubmed
The proposed method of surgical treatment of patients with scar deformations and defects of soft tissues of the anterior abdominal wall and lumbosacral zone was used in 30 patients . - pubmed
Acute dermotension permits to remove large scar defects and restore natural integument in patients with burn trauma . - pubmed
Unilateral hot plate test : a simple and sensitive method for detecting central and peripheral hyperalgesia in mice . - pubmed
The sensitivity and usefulness of the UHP test for performing pain studies in mice is described . - pubmed
Thermoregulatory responses of two mouse Mus musculus strains selectively bred for high and low food intake . - pubmed
We examined the thermoregulatory responses of male and female mice Mus musculus that had been divergently selected on voluntary food intake , corrected for body mass , to produce a high - intake and a low - intake strain . - pubmed
Lower critical temperature in both strains appeared to be around 28 degrees C. At 30 degrees C there was a significant strain effect on resting metabolic rate , with high strain mice having greater metabolism than low strain mice . - pubmed
Thermal conductance was significantly related to strain and sex , mice from the high strain and males having greater thermal conductances than mice from the low strain and females . - pubmed
All patients showed a hypertropia of the fellow eye . - pubmed
All patients were symptomatic prior to strabismus surgery : 4 of 15 patients with " tilt " ( objects appearing subjectively rotated with respect to their true orientation ) ; 2 of 15 patients with diplopia ; and 9 of 15 patients with both . - pubmed
Postoperatively , 7 patients had residual milder symptoms : tilt , 2 patients ; diplopia , 3 patients ; and both , 2 patients . - pubmed
No patient showed binocular function ( stereopsis or motor fusion ) after macular translocation , either before or following strabismus surgery for cyclotorsion . - pubmed
We present a PNET arising from the kidney in a 23 - year - old female patient . - pubmed
The hypophysis was exposed to radiation in 11 patients with prostatic cancer . - pubmed
RESULTS : A 54 - year - old woman underwent conductive keratoplasty for hyperopia . - pubmed
It is important to select patients with limited SCLC who are able to tolerate concurrent chemotherapy and accelerated TRT . - pubmed
However , the type strains of A. - pubmed
Electrophysiological approach to the study of essential tremor in children and adolescents . - pubmed
There are many reports on neurophysiological features in adult - onset essential tremor , but to our knowledge there have been no similar investigations of essential tremor in children . - pubmed
We conducted a neurophysiological study of nine children , six males and three females , with definite essential tremor . - pubmed
Effect of species from the section Monoverticillata , genus Penicillium , on the growth of cabbage seeds and on certain bacterial plant diseases ] . - pubmed
[ Dynamics of immunological indices in patients with neural rheumatism in various modes of therapy ] . - pubmed
Occupational contact dermatitis , with asthma and rhinitis , from camomile in a cosmetician also with contact urticaria from both camomile and lime flowers . - pubmed
[ Renal failure in an HIV patient ] . - pubmed
' Candidatus Phytoplasma cynodontis ' , the phytoplasma associated with Bermuda grass white leaf disease . - pubmed
Bermuda grass white leaf ( BGWL ) is a destructive , phytoplasmal disease of Bermuda grass ( Cynodon dactylon ) . - pubmed
Hypertension and urinary tract infection each were found in 50 % of the patients while 6 ( 30 % ) presented with features of renal failure . - pubmed
Aberrant intracellular calcium signaling in olfactory neurons from patients with bipolar disorder . - pubmed
OBJECTIVE : The authors examined the feasibility of using olfactory receptor neurons from living patients to test whether calcium signaling is altered in a neuronal cell population in bipolar disorder . - pubmed
METHOD : Ratiometric fluorescence photomicroscopy was used to assess basal and stimulus - induced changes in intracellular calcium levels in biopsy - derived olfactory receptor neurons from seven euthymic patients with bipolar disorder who were medication - free , 10 euthymic patients with bipolar disorder who were treated with mood stabilizers , and 17 age- and sex - matched comparison subjects without bipolar disorder . - pubmed
Although the genetic control of melanism has been studied in chickens and other domestic species , little was known about the molecular genetics of melanin distribution in wild birds until recently . - pubmed
Percutaneous cardiopulmonary support ( PCPS ) is a powerful resuscitation tool for patients in cardiogenic shock . - pubmed
We describe the case of a 75 - year - old woman who required extended PCPS for cardiogenic shock secondary to coronary spasm after on - pump beating coronary artery bypass grafting . - pubmed
This technique appears to be useful in treating limb ischemia and may have application in patients with arterial occlusive disease who are dependent on mechanical support . - pubmed
Focal ischemia , which was studied as an experimental stroke model , was induced in 3- and 24 - month - old rats by unilateral common carotid artery occlusion associated with 24 h of hypoxia . - pubmed
In each patient , the coronary risk factors ( CRF ) , such as hypertension , high cholesterol , diabetes mellitus , obesity , positive family history , and smoking were evaluated . - pubmed
New trial awarded over man 's HIV - related fatigue . - pubmed
2 -( 8 - hydroxy-6 - methoxy-1 - oxo-1h-2 - benzopyran-3 - yl ) propionic acid , an inhibitor of angiogenesis , ameliorates renal alterations in obese type 2 diabetic mice . - pubmed
In the present study , we examined the therapeutic efficacy of 2 -( 8 - hydroxy-6 - methoxy-1 - oxo-1H-2 - benzopyran-3 - yl ) propionic acid ( NM-3 ) , a small molecule isocoumarin with antiangiogenic activity , using diabetic db / db mice , a model of obese type 2 diabetes . - pubmed
PATIENTS : Nineteen heterogeneous emphysema patients . - pubmed
Baseline BODE index ( BMI , degree of airflow obstruction and dyspnea , exercise capacity as measured by the 6 - min walk test [ 6MWT ] ) was 7 to 10 in 10 patients ( estimated 4 - year mortality , 80 % ) and 5 to 6 in 9 patients ( estimated 4 - year mortality , 40 % ) . - pubmed
Nonsustained atelectasis was observed within 48 h in 2 of 12 patients with right upper lobe occlusion . - pubmed
PARTICIPANTS : Eighteen patients met inclusion criteria , 10 trauma and 8 surgical . - pubmed
All but 1 patient ( 17/18 ) had resolution of coagulopathic bleeding with rFVIIa , and all clinical responders ( n = 17 ) ( defined as clinical cessation of bleeding within 24 hours determined by either attending surgeon or chief resident progress note ) had a decrease in PT to normal range . - pubmed
Sleep disturbances reported by refractory partial - onset epilepsy patients receiving polytherapy . - pubmed
PURPOSE : Although sleep disturbances are common in epilepsy , few studies examined the prevalence and impact of sleep disturbance in epilepsy patients . - pubmed
METHODS : We surveyed 201 adult partial - onset epilepsy patients taking stable regimens of two or more antiepileptic medications . - pubmed
To determine whether this defect leads to alterations in the internal three - dimensional organization of mitochondrial membranes , we applied electron microscopic tomography to lymphoblast mitochondria from BTHS patients and controls . - pubmed
METHODS : Patients , who underwent uneventful phacoemulsification with intraocular implantation and were referred for Nd : YAG laser capsulotomy owing to PCO , were prospectively examined for the presence of CBS . - pubmed
RESULTS : Of 655 patients referred for capsulotomy , eight had an associated CBS in that eye . - pubmed
The aims of this paper were to determine the serological response to HSV-1 and HSV-2 infection among pregnant women and women of reproductive age and seroprevalence of HSV-1 and HSV-2 antibodies among pregnant women and women of reproductive age . - pubmed
Complex regional pain syndrome in a patient with spinal cord injury : management with pulsed radiofrequency lumbar sympatholysis . - pubmed
OBJECTIVES : To report a case with bilateral lower extremity complex regional pain syndrome ( CRPS ) in a patient with paraplegia occurring following spinal disc herniation surgery , who was treated successfully with pulse radiofrequency ( PRF ) lumbar sympatholysis . - pubmed
RESULTS : The patient underwent a diagnostic sympathetic ganglion blockade with bupivacaine , which resulted in a marked decrease in the pain and edema of the feet . - pubmed
CONCLUSION : When treatment of CRPS fails with conventional modalities , PRF sympatholysis may be used for control of pain and other symptoms in such patients . - pubmed
The level of defense against great spotted cuckoo ( Clamator glandarius ) parasitism in different European populations of magpie ( Pica pica ) depends on selection pressures due to parasitism and gene flow between populations , which suggests the existence of coevolutionary hot spots within a European metapopulation . - pubmed
Percussion and postural drainage have been widely employed for mechanically ventilated patients but have not been shown to reduce ventilator - associated pneumonia or atelectasis . - pubmed
Intrapulmonary percussive ventilation combines percussion with hyperinflation and a simulated cough , but the evidence for intrapulmonary percussive ventilation in mechanically ventilated patients is insufficient to support routine use . - pubmed
PURPOSE : Patients with von Hippel - Lindau disease may require repeat partial nephrectomies to avoid the need for renal replacement therapy . - pubmed
In the last 2 decades , a variety of different molecular typing methods have been developed to differentiate strains of Mycobacterium avium subsp . - pubmed
To further understand this response , we tested enterostatin 's effect in a human hepatoma cell line ( HepG2 cells ) that was subjected to glucose deprivation , a condition known to induce angiogenesis in other tumor cell lines . - pubmed
RESULTS : Among 3,434 patients 266 ( 7.7 % ) developed an incident ischemic cerebrovascular event . - pubmed
Cataract ( 12.47 per 100 ) was the major ocular comorbidity ; high blood pressure ( 21.14 per 100 ) and diabetes mellitus ( 15.99 per 100 ) were the main systemic comorbidities among 415 patients with retinal diseases . - pubmed
The prevalence of low vision on the basis of best - corrected and presenting visual acuity was 0.63 and 2.87 per 100 in 415 patients with retinal disease . - pubmed
Mouse models of Rett syndrome : from behavioural phenotyping to preclinical evaluation of new therapeutic approaches . - pubmed
The discovery of a monogenic origin for RTT and the subsequent generation of RTT mouse models provided a major breakthrough for RTT research . - pubmed
Although the characterization of these mutant mice is far from complete , they recapitulate several RTT symptoms . - pubmed
This review provides an overview of the behavioural domains so far investigated in these models , including the very few mouse data concerning the developmental course of RTT . - pubmed
BACKGROUND : Patients with enterocutaneous fistulas undergo long intensive treatment . - pubmed
METHODS : Consecutive patients treated for enterocutaneous fistula between 1990 and 2005 were eligible for this retrospective study . - pubmed
An aqueous slurry of gamma - irradiated sterilized dried figs was inoculated with toxigenic strains of Aspergillus flavus and Aspergillus parasiticus . - pubmed
[ A case with hand , foot and mouth disease associated with central nervous symptoms related to enterovirus 71 in Beijing ] . - pubmed
Longitudinal prognostic value of serum " free " copper in patients with Alzheimer disease . - pubmed
Hyperlipidemic patients with higher levels of free copper seemed more prone to worse cognitive impairment . - pubmed
These include ( 1 ) updating the definition of SE to make it more clinically relevant , ( 2 ) consideration of faster ways to initiate first - line benzodiazepine therapy in the prehospital environment , ( 3 ) moving to second - line agents more quickly in refractory status in the emergency department , and ( 4 ) increasing detection and treatment of unrecognized nonconvulsive SE in comatose neurologic emergency patients . - pubmed
METHODS : Initially antiproliferating effect of the antisense oligomers was studied in vitro by measuring the rate of tritiated thymidine incorporation into DNA in rat hepatocellular carcinoma cells in culture medium . - pubmed
Based on the findings , the antisense treatment was carried out in rat hepatocarcinogenesis model - initiated with diethylnitrosamine and promoted using 2 - acetylaminoflourene . - pubmed
Primary osteoplasty using calvarian bone in patients with cleft lip , alveolus and palate . - pubmed
METHODS : After primary osteoplasty with calvarian bone at an average age of 24 months ( 4 - 56 months ) radiographic assessment was carried out in 31 patients with 40 alveolar clefts . - pubmed
METHODS : A matrix - associated transepithelial resistance invasion ( MATRIN ) assay was used to assess SFs from patients with RA in comparison with SFs from patients with osteoarthritis ( OA ) . - pubmed
METHODS A total of 300 refractory FD patients and 450 healthy blood donors ( BD ) were studied . - pubmed
Assessment of progenitor cell responses to pathogenic intestinal bacteria could provide a measure of predisposition for apoptotic enterocyte - assisted intestinal dysplasias in humans . - pubmed
In both strains , subAB was physically associated with tia , an invasion genetic determinant of enterotoxigenic E. - pubmed
Role of video - assisted thoracoscopy in patients with ovarian cancer and pleural effusion . - pubmed
METHODS : We retrospectively evaluated 16 VAT procedures in 15 patients with advanced ovarian malignancies and pleural effusions . - pubmed
RESULTS : Common causes for admitting children to intensive care units are head injuries ; septic shock and respiratory failure . - pubmed
Non - invasive pressure ventilation is used increasingly in children with respiratory failure . - pubmed
Development of tolerance , withdrawal symptoms and physical dependency are substantial clinical problems in long - term sedation and analgesic treatment of children , and are associated with high doses and long duration of infusions . - pubmed
The patient was initially treated for ST - segment elevation myocardial infarction and symptoms resolved . - pubmed
DISCUSSION : Takotsubo cardiomyopathy is commonly triggered by severe emotional or psychological stress and occurs primarily in postmenopausal women . - pubmed
CONCLUSIONS : Takotsubo cardiomyopathy causes a reversible left ventricle dysfunction which occurs most commonly in postmenopausal women with or without cardiovascular disease . - pubmed
It is likely that these findings , as well as the paucity of tobacco dependence studies , reflect the relatively small number of psychiatric nurses conducting research as well as the inattention , until recently , of mental health leaders , policy makers , and funders to the importance of tobacco dependence research in this clinical population . - pubmed
As tobacco dependence treatment for those with mental illnesses and/or addictive disorders becomes more of a public health priority , opportunities abound for nurse researchers to contribute to the growing evidence in this often neglected area . - pubmed
The expression of the above genes was measured in the circulating cancer cells of pancreatic cancer patients . - pubmed
We compared their expression rate in pancreatic cancer patients at different stages to screen for the indicator with highest sensitivity and specificity for the detection of circulating pancreatic cancer cells . - pubmed
Energy expenditure during sleep , sleep deprivation and sleep following sleep deprivation in adult humans . - pubmed
These findings provide support for the hypothesis that sleep conserves energy and that sleep deprivation increases total daily EE in humans . - pubmed
METHODS : Between June 2004 and June 2005 we observed 471 patients with PPV . - pubmed
Out of these , five transformed into the geotropic form during the first examination ; in 5 patients we observed geotropic nystagmus at the follow - up visit ; the last 20 never showed geotropic nystagmus before resolution . - pubmed
Recent randomized controlled trials , however , have failed to demonstrate the efficacy of therapeutic hypothermia ( TH ) in patients with TBI . - pubmed
We quantified changes in chronically retracted tendons undergoing no repair or a staged repair involving an initial re - lengthening of the musculotendinous unit by traction in a sheep model of massive rotator cuff tear . - pubmed
Wound catheters provided no significant analgesia at rest or on activity , except in patients undergoing gynecological and obstetric surgery at 48 h ( P=0.03 ) . - pubmed
No significant differences in side effects were found , except for a lower risk of wound breakdown ( P=0.048 ) and a shorter length of hospital stay ( P=0.04 ) in patients receiving LA . - pubmed
LA injected via wound catheters did not reduce pain intensity , except at 48 h in a subgroup of patients undergoing obstetric and gynecological surgery . - pubmed
The purpose of this study was to retrospectively evaluate the complications of 58 patients who underwent surgery for mandibular condylar process fractures . - pubmed
There were 22 patients with bilateral condyle fractures and 36 patients with unilateral condyle fractures , accounting for 65 surgeries . - pubmed
Treatment outcomes for different subgroups of nasopharyngeal carcinoma patients treated with intensity - modulated radiation therapy . - pubmed
Herein , we evaluated the outcomes of NPC patients treated with IMRT and further explored treatment strategy to improve such outcome . - pubmed
Our results suggest that the decision of treatment strategy for NPC patients should consider combinations of T and N stages , and that IMRT alone for early stage NPC patients can produce satisfactory results . - pubmed
OBJECTIVE : The long - term event monitoring ( LEM ) study evaluated the lipid - lowering efficacy and safety of fluvastatin in Japanese patients with hypercholesterolemia . - pubmed
Presence of diabetes mellitus ( DM ) in patients without complication significantly increased the incidence in both cardiac events ( 2.37 ) and cerebral events ( 2.15 ) as compared with non - DM patients for primary prevention ( P & lt ; 0.001 and P & lt ; 0.01 , respectively ) . - pubmed
For the secondary prevention , DM patients with complication of cardiac disease showed a significantly higher incidence in both cardiac events ( 1.59 ) and cerebral events ( 3.79 ) compared with non - DM patients ( P & lt ; 0.05 and P & lt ; 0.01 , respectively ) . - pubmed
In contrast , DM patients with complications of cerebrovascular disease showed a significantly higher incidence in cerebral events ( 2.58 , P & lt ; 0.05 ) , but not cardiac events compared with non - DM patients . - pubmed
For secondary prevention , hypertension in patients with complication of cardiac or cerebrovascular disease did not affect incidence in both cardiac and cerebral events . - pubmed
Alterations of high - mannose type N - glycosylation in human and mouse osteoarthritis cartilage . - pubmed
METHODS : Alterations in N - glycans were analyzed in human OA cartilage and degraded mouse cartilage by high - performance liquid chromatography and mass spectrometry . - pubmed
RESULTS : Alterations in high - mannose type N - glycans were observed in both human OA cartilage and degraded mouse cartilage . - pubmed
The parasite Leishmania donovani is reported to be the causative agent for CL in Sri Lanka . - pubmed
Eight patients with postoperative recurrent uterine cancer received HDR - ISBT with or without external beam radiotherapy using our unique ambulatory technique . - pubmed
melitensis and Brucella abortus infections in mice . - pubmed
Low - dose theophylline restores corticosteroid responsiveness in rats with smoke - induced airway inflammation . - pubmed
Patients with chronic obstructive pulmonary disease ( COPD ) respond poorly to corticosteroids . - pubmed
Imaging mass spectrometry to visualize biomolecule distributions in mouse brain tissue following hemispheric cortical spreading depression . - pubmed
Transient elastography to rule out esophageal varices and portal hypertensive gastropathy in HIV - infected individuals with liver cirrhosis . - pubmed
BACKGROUND / AIMS : It is recommended that patients with cirrhosis undergo endoscopic screening to rule out the presence of gastroesophageal varices : a noninvasive predictive method to identify cirrhotic patients with a very low risk of esophageal varices could potentially avoid unnecessary endoscopies . - pubmed
METHODS : We studied in 85 HIV - infected patients with cirrhosis the association between the absence of esophageal varices and portal hypertensive gastropathy , assessed by endoscopy , and liver stiffness measurement by transient elastography . - pubmed
CONCLUSION : Transient elastography combined with platelet count is useful for predicting the absence of esophageal varices and portal hypertensive gastropathy and , therefore , avoid unnecessary diagnostic endoscopies in HIV - infected patients with liver cirrhosis . - pubmed
Denosumab ( Dmab ) and zoledronic acid ( ZOL ) are antiresorptive agents , with different mechanisms of action , that are indicated for delaying the onset of skeletal - related events in patients with bone metastases from solid tumors . - pubmed
Dmab ( 0.31 to 160 muM ) had no effect on the viability of human MDA - MB-436 and CG5 breast cancer cells or human umbilical vein endothelial cells ( HUVECs ) and no effect on tubule formation or invasion of HUVECs . - pubmed
Usefulness of whole - body fluorine-18 - fluorodeoxyglucose positron emission tomography in patients with neurofibromatosis type 1 : a systematic review . - pubmed
To systematically review the role of positron emission tomography ( PET ) with fluorine-18 - fluorodeoxyglucose ( FDG ) in patients with neurofibromatosis type 1 ( NF1 ) . - pubmed
Only those studies or subsets in studies including whole - body FDG - PET or PET / CT scans performed in patients with NF1 were included . - pubmed
We identified 12 studies including 352 NF1 patients . - pubmed
Moreover , FDG - PET seems to be an important imaging modality for predicting the progression to MPNST and the outcome in patients with MPNST . - pubmed
Two studies evaluated the role of FDG - PET in pediatric patients with NF1 . - pubmed
The horse had tachypnea with increased respiratory effort and was in thin body condition . - pubmed
EMPF is a recently described disease in adult horses with clinical signs of fever , weight loss and respiratory problems . - pubmed
The pathological findings include loss of functional pulmonary parenchyma due to extensive nodular interstitial fibrosis which has been related to infection with the equine herpesvirus type 5 ( EHV-5 ) . - pubmed
Preliminary studies on the hypoglycemic effect of Peganum harmala L. Seeds ethanol extract on normal and streptozotocin induced diabetic rats . - pubmed
Peganum harmala L. ( Zygophyllaceae ) is a traditional medicine used for the treatment of variety of human ailments , including antidepression , hallucination , antileishmaniasis etc . - pubmed
We report for first time the hypoglycemic activity of the ethanolic extract of this plant at two dose levels of 150 and 250mg / kg bw in sucrose challenged normal as well as in rats with streptozotocin induced diabetes . - pubmed
The oral administration of ethanolic extract causes maximum fall of blood glucose level to 22.9 % ( p<0.05 ) and 29.4 % ( p<0.01 ) respectively with the two doses in normal and 30.3 % ( p<0.01 ) and 48.4 % ( p<0.001 ) in diabetic rats . - pubmed
The standard drug metformin treated group showed 28.0 % ( p<0.01 ) and 45.5 % ( p<0.001 ) respectively in normal and diabetic rats . - pubmed
harmala is as effective as metformin in reducing the blood glucose levels of normoglycemic and streptozotocin - induced diabetic rats . - pubmed
METHODS : A total of 74 patients with acne and of 88 healthy control subjects from Catania , Italy were examined in the present study . - pubmed
A total of 60 male rats ( 145 + - 2.52 g ) were grouped into four : A , B , C and D , where group A ( the control ) received 1 mL of distilled water orally while those in groups B , C and D ( test groups ) received orally , same volume of trona preparation corresponding to 100 , 200 and 400 mg / kg body weight , respectively , for 28 days . - pubmed
An outbreak of acute Schistosoma mansoni Schistosomiasis in a nonendemic area of Brazil : a report on 50 cases , including 5 with severe clinical manifestations . - pubmed
METHODS : From December 2009 to March 2010 , the 50 patients with acute schistosomiasis ( group 1 ) bathed in a swimming pool supplied by a brook on a country estate in the outskirts of Sao Joao del Rei , Brazil . - pubmed
Group 1 patients more frequently had cercarial dermatitis ( P = .01 ) , blood in the stool ( P = .04 ) , and intra - abdominal lymph nodes ( P = .001 ) . - pubmed
All group 1 patients were treated with praziquantel ; 1 patient with myeloradiculopathy also received oral prednisone ( 60 mg / day ) for 6 months with complete recovery . - pubmed
Female C57BL/6 mice underwent coronary occlusion and reperfusion ; 2 days later , 10(5 ) male mouse CSCs were injected intramyocardially . - pubmed
The strains induced accumulation of phenolic compounds in pea leaves and the amount increased when such leaves were get inoculated with E. - pubmed
Between the two strains , Pag was found to be more effective than Pf4 as its effect was more persistent in pea leaves . - pubmed
The results indicate that GED-0507 - 34L possesses anti - inflammatory properties useful for the management of patients with inflammatory skin diseases including psoriasis . - pubmed
MATERIAL AND METHODS : In a retrospective study , 25 PC patients , 14 FP patients , and 25 subjects with a normal pancreas underwent breath - hold diffusion - weighted imaging ( DWI ) on a 3.0 T magnetic resonance ( MR ) scanner . - pubmed
Such effect is more obvious in the overweight patients . - pubmed
Estimated glomerular filtration rate is an easy predictor of venous thromboembolism in cancer patients undergoing platinum - based chemotherapy . - pubmed
Serum creatinine and eGFR were evaluated before the start of standard platinum - based chemotherapy in a cohort of 322 consecutive patients with primary or relapsing / recurrent solid cancers , representative of a general practice population . - pubmed
METHODS : We retrospectively reviewed our experiences with 38 patients with vaginal agenesis treated with primary surgery from June 2006 to April 2012 . - pubmed
RESULTS : A total of 38 patients ( 33 with Mayer - Rokitansky - Kuster - Hauser syndrome and five with complete androgen insensitivity syndrome ) were included in the present study . - pubmed
CONCLUSION : Transvestibular vaginoplasty with autologous buccal micromucosa is an effective and feasible approach for patients with Mayer - Rokitansky - Kuster - Hauser syndrome and complete androgen insensitivity syndrome . - pubmed
Three patients with HNF1beta - MODY were found to have dorsal pancreatic agenesis and four of them had whole - gene deletion . - pubmed
Calcification of the stylohyoid ligament in panoramic radiography and cone beam computed tomography among patients referred for dental implant treatment planning . - pubmed
The objective of this study was to evaluate the incidence of calcified SHL detected on cone beam computed tomography ( CBCT ) scans and panoramic radiographs ( PR ) in patients referred for dental implant therapy . - pubmed
CONCLUSION : CBCT was more accurate in determining the pattern and extent of calcification of the SHL in patients undergoing implant treatment planning . - pubmed
Predictors of failure of conservative treatment among patients with emphysematous pyelonephritis . - pubmed
The aim of this study is to analyze the predictors associated with failure of conservative treatment among patients with EPN and offer the recommendation of appropriate empirical antibiotic regimen . - pubmed
METHODS : From January 2001 to December 2013 , 44 consecutive patients were diagnosed with EPN . - pubmed
Need for emergency hemodialysis , shock on initial presentation , altered mental status , severe hypoalbuminemia , inappropriate empirical antibiotic treatment and polymicrobial infections were significantly more common in the patients who died compared with the survivors . - pubmed
Even in the patients treated with percutaneous drainage plus effective antibiotics , failure was still associated with severe hypoalbuminemia ( p = 0.01 ) . - pubmed
CONCLUSIONS : Both appropriate empirical antibiotic and percutaneous drainage were essential for patients with EPN . - pubmed
Patients with severe hypoalbuminemia had a higher risk of conservative treatment failure , and additional management may be required . - pubmed
These compounds therefore have significant potential for future development of chemotherapeutic agents for patients suffering from breast cancers and parasitic infection . - pubmed
OBJECTIVE : The complexities of post - stroke spasticity ( PSS ) , and the resultant difficulties in treating the disability , present a significant challenge to patients , stroke rehabilitation teams , and caregivers . - pubmed
Reducing the severity of spasticity and its long - term complications may be facilitated by early intervention , making identification of stroke patients at high risk for developing spasticity essential . - pubmed
The patients were classified into 3 groups : mild AP , moderately severe AP , and severe AP . - pubmed
RESULTS : Acute pancreatitis was considered severe in 16 ( 15 % ) patients , moderately severe in 25 ( 24 % ) patients , and mild in 63 ( 61 % ) patients . - pubmed
Cardiovascular events are the main cause of morbidity and mortality in CKD patients . - pubmed
We have studied the effects of cell communication on human beta cell function and resistance to cytotoxicity using the novel human insulin - secreting cell line 1.1B4 configured as monolayers and pseudoislets . - pubmed
Thus , this study aims to investigate the direct inhibitory effect of stachyose on human colon cancer cells and determine the molecular mechanism underlying this effect . - pubmed
Vanadium toxicity is a challenging problem to human and animal health with no entirely understanding cytotoxic mechanisms . - pubmed
Besides , vanadium induced mitochondrial / lysosomal toxic interaction and vanadium reductive activation mediated by glutathione in vanadium toxicity was significantly ( P & lt ; 0.05 ) ameliorated by Sesamum indicum extracts . - pubmed
METHODS : Sera from 19 patients with HCV genotype 1 infection and compensated cirrhosis who failed to respond to a prior course of Peg - IFN / RBV were selected at time 0 before starting triple therapy with boceprevir or telaprevir . - pubmed
RESULTS : Patients baseline characteristics were similar to the well - defined CUPIC cohort ( age , HCV subtype , baseline viremia , and treatment history ) . - pubmed
Cytotoxic activity of Macrosolen parasiticus ( L. ) Danser on the growth of breast cancer cell line ( MCF-7 ) . - pubmed
, This study was aimed to investigate the anti - cancer activity of methanolic and aqueous extract of stem of M. - pubmed
MATERIALS AND METHODS : The extracts were tested in human breast cancer cell lines in vitro for percentage cytotoxicity , apoptosis by acridine orange / ethidium bromide staining , LD50 and IC50 values after treatment with M. - pubmed
MAIN OBSERVATIONS : The authors report the clinical , dermoscopic and histopathological features of a hemosiderotic dermatofibroma mimicking melanoma in an 85 - year - old woman . - pubmed
Here , rapamycin mediated apoptosis were investigated in human retinoblastoma Y79 cells . - pubmed
Together , all these results illustrated that rapamycin induced apoptosis in human retinoblastoma Y79 cells involvement of both intrinsic and extrinsic pathways . - pubmed
The spreading of an infectious disease can trigger human behavior responses to the disease , which in turn plays a crucial role on the spreading of epidemic . - pubmed
CASE REPORT : An 84 - year - old woman presented to our ED with a painless acute vision loss in her right eye . - pubmed
Here we will review the results , mainly published in the last five years , of unbiased proteomics and peptidomics approaches for biomarker research using biological fluids of Alzheimer ' s , Parkinson 's and Amyotrophic Lateral Sclerosis patients . - pubmed
This systematic review aimed to evaluate the literature on the acquisition- , reconstruction- and analysis parameters of micro - computed tomography ( micro - CT ) for the assessment of periapical lesions in rats and mice , and to illustrate the effect of variation in these parameters . - pubmed
The PubMed database was searched from 2000 to January 2015 ( English - language publications ) for reports on the use of micro - CT to evaluate periapical lesions in rats and mice . - pubmed
To illustrate the effect of variations in acquisition- , reconstruction- , and analysis parameters on images of periapical lesions , micro - CT examination of two hemi - mandibles of mice , with periapical lesions around the first molar was undertaken . - pubmed
Twenty - one studies were identified , which analysed periapical lesions in rats or mice using micro - CT . - pubmed
There is no defined protocol for acquiring and analysing micro - CT images of periapical lesions in rats and mice . - pubmed
PURPOSE : Substance use behaviors often emerge during adolescence , and adolescents with type 1 diabetes ( T1D ) may be at risk for engaging in traditional substance use ( eg , alcohol , tobacco , and illicit substances ) as well as a unique form of substance use : insulin misuse . - pubmed
METHODS : Sixty adolescents aged 12 to 20 years with T1D ( n = 60 ) completed surveys on substance use , insulin misuse , and diabetes self - management during a routine diabetes appointment . - pubmed
Analgesic effect of repetitive transcranial magnetic stimulation ( rTMS ) in patients with chronic low back pain . - pubmed
The objective of the present study was to assess the benefits of 1 - week repetitive transcranial magnetic stimulation ( rTMS ) in patients with chronic low back pain ( LBP ) . - pubmed
Eighty - two patients diagnosed with LBP were divided randomly into three groups : rTMS - treated group , sham group , and physical therapy - treated group . - pubmed
Moreover , patients who received rTMS had a lower mean pain score than patients treated with physical therapy . - pubmed
Our study suggests that rTMS produces safe , significant , and long - term relief in patients with LBP without evident side effects . - pubmed
METHODS : A retrospective review of 21 consecutive patients who underwent diffusion - weighted PROPELLER magnetic resonance imaging ( MRI ) on a 1.5 T MRI scanner prior to primary or revision / second - look surgery for suspected cholesteatoma from 2009 - 2012 was performed . - pubmed
KTRs after SOT , however , show higher incidences of EBV viremia and PTLD , sepsis , and death from sepsis . - pubmed
We recently reported that the number of BM - derived stem cells ( SCs ) increases in patients with pancreatic and stomach cancer . - pubmed
In conclusion , mobilization of SCs in cancer patients depends on the type of malignancy and its ability to activate pro - mobilization cascades . - pubmed
Prognostic Role of Preoperative Serum Lipid Levels in Patients Undergoing Radical Prostatectomy for Clinically Localized Prostate Cancer . - pubmed
BACKGROUND : The prognostic role of preoperative serum lipid levels in patients undergoing radical prostatectomy ( RP ) for clinically localized prostate cancer ( PCa ) is unclear . - pubmed
The aim of the present study was to investigate preoperative serum lipid levels in patients with clinically localized PCa undergoing RP and their association with clinicopathological features and oncological outcome . - pubmed
Recurrence occurred in 49 patients ( 15.4 % ) at a median time of 18 months ( 2 - 51 month ) . - pubmed
Comparison of dose distribution for head and neck cancer patients with and without dose painting escalation during radiotherapy realized with tomotherapy unit . - pubmed
OBJECTIVE : To determine and quantify the percentage dose increase to organs at risk ( OARs ) with multiple - level dose painting ( DP ) for patients with head and neck cancer in comparison with standard regimen . - pubmed
Similarly , the role of diet rich in polyphenols and plant polysaccharides in modulating gut bacteria and its impact on diabetes and obesity have been the subject of investigation by several research groups . - pubmed
METHODS : Nine females performed two 5 - d HA interventions ( controlled hyperthermia Tre>=38.5 C ) , separated by 7 - wk , during the follicular phase of the menstrual cycle confirmed by plasma concentrations of 17 - beta estradiol and progesterone . - pubmed
A total of 71 consecutive patients with closed Sanders type 2 calcaneal fractures were enrolled and divided into two groups according to the treatment to which they chose : the EFLIF group and the ORIF group . - pubmed
BACKGROUND : Bacillus Calmette - Guerin ( BCG ) is the most effective initial intravesical therapy for high - grade non - muscle invasive bladder cancer , but many patients still fail . - pubmed
Patients received maintenance if recurrence - free . - pubmed
RESULTS : Fifty - two patients received treatment with a median recurrence follow - up of 16.3 months and overall follow - up of 41.8 months . - pubmed
No patients had positive surgical margins or positive lymph nodes . - pubmed
CONCLUSIONS : In patients with non - muscle - invasive bladder cancer with prior BCG failure , quadruple immunotherapy demonstrated good treatment success in some patients and warrants further evaluation . - pubmed
We report our experience implementing this haplo - HSCT for high - risk malignancies in pediatric patients focusing on the conditioning regimen . - pubmed
Thus , total body irradiation ( TBI ) based regimen was introduced in the following 10 patients and resulted in engraftment in all patients . - pubmed
Compared to patients conditioned with chemotherapy , patients conditioned with TBI had superior actuarial overall survival ( 66 % vs. 37 % , P = 0.05 ) and event - free survival ( 61 % vs. 33 % , P = 0.04 ) . - pubmed
Similarly , whole brain concentrations of GABA were not significantly altered in either knockout mouse strain at 3 or 18 mo of age , as compared to WT . - pubmed
OBJECTIVE : This prospective study uses calf bioimpedance spectroscopy ( cBIS ) to guide the attainment of dry weight ( DWcBIS ) in chronic hemodialysis ( HD ) patients . - pubmed
Twenty - eight patients ( 25 % diabetes ) achieved DWcBIS , whereas 32 patients ( 47 % diabetes ) did not . - pubmed
Ratios of intradialytic changes in calf normalized resistivity , ECV , and ECV / TBW to ultrafiltration volume were significantly lower in diabetic than in non - diabetic patients . - pubmed
The atrial conduction disorder in patients with atrial pacing results in higher incidence of atrial fibrillation . - pubmed
Studies have shown that low interatrial septal pacing is superior to right atrial appendage pacing in preventing persistent or permanent atrial fibrillation in these patients . - pubmed
PATIENTS AND METHODS : We describe a 73 - year - old man with a history of advanced primary open - angle glaucoma who had previously undergone an unsuccessful micropulse transcleral cyclophotocoagulation of the left eye . - pubmed
Vitamin D deficiency was more common in children older than 1 years than in children aged 1 year or younger , and vitamin D deficiency was 2 72 times more likely in girls than in boys ( 95 % CI 1 21 - 6 01 ; p=0 037 ) . - pubmed
Approximately 20 to 40 % of patients with type 1 or type 2 diabetes develop diabetic kidney disease . - pubmed
Regular , systematic screening for diabetic kidney disease is needed to identify patients at risk for , or with presymptomatic stages of diabetic kidney disease . - pubmed
In this article , a patient having otologic symptoms as a result of spontaneous herniation of TMJ into EAC was presented in the light of current literature . - pubmed
Previously we validated a challenge model that utilized a dose of 2x107 CFU of ETEC strain H10407 ( LT+ , ST+ , CFA / I+ and O78 + ) to induce attack rates for moderate to severe diarrhea ( MSD ) of ~60 - 70 % . - pubmed
Cognitive Profile of Children With Intracranial Germ Cell Tumor According to Tumor Location . - pubmed
PURPOSE : The purpose of this study was to evaluate the long - term cognitive sequelae and to describe the neuropsychological profile of patients with intracranial germ cell tumors according to tumor location ( pineal or suprasellar site ) . - pubmed
CONCLUSIONS : Overall cognitive abilities were preserved in children treated for central nervous system germ cell tumor . - pubmed
Eyes were grouped as non - diabetic controls ( 37 eyes ) , patients with diabetes mellitus ( DM ) without diabetic retinopathy ( DM without DR , 31 eyes ) , non - proliferative diabetic retinopathy ( NPDR , 41 eyes ) and proliferative diabetic retinopathy ( PDR , 27 eyes ) . - pubmed
These findings are consistent with previous observations in anesthetized dogs and indicate that the prokinetic effects of LMN - NKA may be achieved without hypotension using a route of administration that avoids unnecessarily high plasma exposures . - pubmed
BACKGROUND : Human infection of avian influenza virus ( AIV ) remains a great concern . - pubmed
Although live poultry markets are believed to be associated with human infections , ever more infections have been reported in rural areas with backyard poultry , especially in the fifth epidemic of H7N9 . - pubmed
First , minimally invasive heart rate ( fH ) measurements were made during a thermal ramp until cardiac failure in C. - pubmed
Salmonella Enteritidis became the main serovar isolated from gastroenteritis cases in Brazil after the 90 's . - pubmed
In conclusion , our results showed that the genomic profile of Salmonella Enteritidis strains isolated in Brazil shifted after 1994 , replaced by a global epidemic group of strains . - pubmed
It may be hypothesized that the presence of the prophage SE20 might have conferred to these strains a better ability to colonize chicken and consequently to infect and cause disease in humans , which might better explain the increase in the number of S . - pubmed
Effects of the Problem Solving Technique in Type 2 Diabetic Patients with Cognitive Impairment : A Randomized Clinical Trial . - pubmed
This study aimed to evaluate the effects of problem - solving technique in type 2 diabetic patients with cognitive impairment . - pubmed
96 type 2 diabetic patients with cognitive impairment were randomly divided into two groups . - pubmed
Conclusion : Applying problem - solving technique significantly enhanced self - management , quality of life and metabolic indexes in type 2 diabetic patients with cognitive impairment . - pubmed
Clinical significance of radiological pleuroparenchymal fibroelastosis pattern in interstitial lung disease patients registered for lung transplantation : a retrospective cohort study . - pubmed
This study evaluated the clinical significance of radiological PPFE as an isolated finding or associated with other interstitial lung diseases ( ILDs ) in patients having fibrotic ILDs and registered for cadaveric lung transplantation ( LT ) . - pubmed
METHODS : This retrospective study included 118 fibrotic ILD patients registered for LT . - pubmed
Objective : To assess the usefulness of modified esophagogastroduodenoscopy ( EGD ) for the detection of second primary malignancies of the esophagus or hypopharynx in patients with oral squamous cell carcinoma and determine the association between the oral lesion subsite and esophageal or hypopharyngeal lesion occurrence . - pubmed
Methods : In total , 166 patients with oral squamous cell carcinoma without any established symptoms of esophageal or hypopharyngeal squamous cell carcinoma underwent modified EGD based on the Valsalva maneuver and U - turn method , image - enhanced endoscopy , and chromoendoscopy using Lugol ' s iodine for diagnosis . - pubmed
Conclusions : Modified EGD is an effective noninvasive technique for early diagnosis and treatment of second primary malignancies of the esophagus and hypopharynx in patients with oral squamous cell carcinoma . - pubmed
High expression of miR-665 exhibited more severe tumor size , vascular invasion and Edmondson grading in HCC patients . - pubmed
The use of gene expression to unravel the single and mixture toxicity of abamectin and difenoconazole on survival and reproduction of the springtail Folsomia candida . - pubmed
The aim of the present study was to evaluate the single and binary mixture toxicity of commercial products of abamectin ( Kraft 36 EC ) and difenoconazole ( Score 250 EC ) to Folsomia candida . - pubmed
To investigate brain abnormalities in adolescents with new - onset bipolar disorder ( BD ) during acute hypomanic and depressive episodes using electroencephalogram ( EEG ) analysis and to derive a computer - based method for diagnosis of the disorder . - pubmed
METHODS : During CLARINET , patients with metastatic intestinal / pancreatic NETs received lanreotide depot / autogel 120 mg or placebo every 4 weeks for 96 weeks . - pubmed
Treatment of severe ventriculitis caused by extensively drug - resistant Acinetobacter baumannii by intraventricular lavage and administration of colistin . - pubmed
All patients underwent neurosurgery before infection , and all A. - pubmed
Of the 20 patients who were cured , eight underwent shunt surgery due to hydrocephalus before they were discharged to a rehabilitation center . - pubmed
Five patients died , including one who was re - admitted due to recurrence 1 month after discharge . - pubmed
Conclusions : IVT lavage and colistin treatment may be an effective treatment for SV caused by extensively drug - resistant A. - pubmed
Combining these two modes of action has been shown to improve glucose and lipid metabolism , and to improve the overall cardiovascular risk in patients with Type 2 diabetes . - pubmed
The purpose of this review is to evaluate the clinical data that has been published on this combination , appearing to represent a convenient way to obtain therapeutic targets in patients with Type 2 diabetes mellitus . - pubmed
It is prudent to include metabolic disorders in the differential diagnosis because in some cases , gastrointestinal symptoms may be the only presenting feature in a patient with an underlying IEM . - pubmed
Aim To describe a therapeutic approach , indications for abdominoperineal resection ( APR ) , survival and oncological results for patients who received treatment in our surgical clinic for anal canal squamous cell cancer ( SCC ) . - pubmed
Results Eighteen patients with anal canal SCC were included in the study ; 11 ( 61.1 % ) patients were in Group 1 and 7 ( 38.8 % ) in Group 2 . - pubmed
Early surgical intervention and cessation of seizure activity are important for children with intractable epilepsy . - pubmed
This paper reviews the seizure and cognitive outcomes of epilepsy surgery for FCD in children . - pubmed
CASE REPORT : A 72 - year - old male patient presented to the emergency department with a 10 - day history of generalized rash , generalized muscle and joint pain and high fever . - pubmed
The patient responded rapidly to corticosteroids and the skin lesions improved . - pubmed
RESULTS : Of 132 patients , 41 ( 31.1 % ) developed POD . - pubmed
Administration of Asian Herb Bennet ( Geum japonicum ) Extract Reverses Depressive - Like Behaviors in Mouse Model of Depression Induced by Corticosterone . - pubmed
Geum japonicum , commonly known as Asian herb bennet , has been used as a diuretic , astringent , anti - dizziness , and anti - headache agent in traditional medicine . - pubmed
japonicum extract using depressive - like behavior induced in mice through daily injection of corticosterone ( CORT ) . - pubmed
We report a case of a man with Castleman disease and monoclonal gammopathy , with a history of chronic diarrhoea and asthenia . - pubmed
Frequently , these patients present fatigue , weight loss and sarcopenia with reduction of performance status , limiting subsequent therapeutic options . - pubmed
BACKGROUND : The ongoing threat of the new coronavirus SARS - CoV2 pandemic is alarming and strategies for combating infection are highly desired . - pubmed
Antihyperglycemic properties of hydroxychloroquine in patients with diabetes : Risks and benefits at the time of COVID-19 pandemic . - pubmed
Preliminary studies have shown the safety and efficacy of HCQ ( at a dose ranging from 400 to 600 mg / day ) in patients with type 2 diabetes over a short - term period . - pubmed
In 2014 , HCQ has been approved in India as an add - on hypoglycemic agent for patients with uncontrolled type 2 diabetes . - pubmed
However , large randomized controlled trials are needed to establish the safety and efficacy profile of HCQ in patients with type 2 diabetes over a long - term period . - pubmed
The aim of this manuscript is to comprehensively summarize the current knowledge on the antihyperglycemic properties of HCQ and to critically evaluate the potential risks and benefits related to HCQ use in patients with diabetes , even in light of the current pandemic scenario . - pubmed
Promising signs for tackling bovine TB . - pubmed
ADVL1522 : A phase 2 study of lorvotuzumab mertansine ( IMGN901 ) in children with relapsed or refractory wilms tumor , rhabdomyosarcoma , neuroblastoma , pleuropulmonary blastoma , malignant peripheral nerve sheath tumor , or synovial sarcoma - A Children 's Oncology Group study . - pubmed
METHODS : Eligible patients had relapsed after or progressed on standard therapy for their tumor type . - pubmed
One patient with rhabdomyosarcoma had a partial response , and 1 patient with synovial sarcoma achieved a delayed complete response . - pubmed
Reproductive Diseases in Farmed Rabbit Does . - pubmed
In this case , the median of the prevalence of apparent infertility was 14.5 % ( minimum to maximum : 4.1 - 50 % ) , which could be considered baseline occurrence when monitoring the theriogenology of rabbit doe farms . - pubmed
Of these , 3 studies have shown that vitamin D supplementation does not alter glycemic control markers in pre - diabetic individuals . - pubmed
Methods : We reviewed the data of 3,612 patients with breast cancer treated with radiotherapy ( RT ) between January 2010 and December 2016 . - pubmed
Clinical outcomes of hyperbaric oxygen therapy in treatment of postoperative chronic Pseudomonas aeruginosa wound infection following implant reconstruction of the breast . - pubmed
Emotional disorders induced by MA abuse have been widely reported both in human and animal models ; however , the mechanisms underlying such disorders have not yet been fully elucidated . - pubmed
In this study , a chronic MA administration mouse model was utilized to elucidate the serotonergic pathway involved in MA - induced emotional disorders . - pubmed
After 4 weeks of MA administration , the animals exhibited significantly increased depressive and anxious symptoms . - pubmed
We describe a patient with severe head injury who deteriorated three weeks after trauma due to late development of ventricular septal rupture . - pubmed
Cyclacillin was compared with ampicillin by its bacteriostatic efficiency in vitro , chemotherapeutic efficiency in experimental infections of mice and rats and pharmacokinetic characteristics . - pubmed
[ Restoration of sexual function in latent ketosis in cows ] . - pubmed
[ Hydrocortisone for the treatment of cerebral vasopasm--(1 ) experiments in dogs ( author 's transl ) ] . - pubmed
Psychomotor skills in depressed out - patients treated with L - tryptophan , doxepin , or chlorimipramine . - pubmed
Psychomotor skills were measured in depressed out - patients during three - week double - blind treatment with 1 - tryptophan ( 16 patients ; 0.5 - -1.0 g t.i.d . ) - pubmed
The effect of depression on psychomotor skills was evaluated by comparing the results from the pre - drug scores ( 29 patients ) with the respective performances of a matched reference group ( 20 healthy volunteers ) . - pubmed
The comparative ventilatory responsiveness to CO2 was studied in 13 chronic bronchitics and 14 emphysematous patients , all exhibiting respiratory insufficiency and with FEV1 less than 1,500 ml . - pubmed
parvum to both intact and thymectomized mice resulted in the appearance in the peritoneal exudate of cells which inhibited tumour growth in vitro . - pubmed
This study was performed to investigated the relationship between cross sectional areas of glomerular arterioles and glomerular volume in rats with puromycin aminonucleoside ( PAN)-induced nephrosis , which is an experimental model of glomerular sclerosis . - pubmed
A phagocytic assay performed with human peripheral mononuclear cells and malaria - infected erythrocytes enabled the study of opsonizing antibodies in human serum from donors presenting different levels of protective immunity . - pubmed
Serum hepatitis C virus sequences in posttransfusion non - A , non - B hepatitis . - pubmed
We investigated 17 patients ( 12 males and 5 females , ages 2 to 57 years old ) with posttransfusion non - A , non - B hepatitis to determine relationships between clinical courses and hepatitis C virus ( HCV ) markers . - pubmed
With respect to clinical course , HCV RNA was detected in six of eight patients ( 75 % ) with chronic biochemical disease , and in two of five patients ( 40 % ) with biochemically resolved chronic disease . - pubmed
HCV RNA was not detectable in convalescent sera from four patients with acute disease . - pubmed
Thus , PCR is useful in determining the persistence of HCV infection as well as to diagnose anti - HCV negative HCV infection . - pubmed
[ Anesthesiologic management of surgery of the aorta and the major vessels in patients with diabetes mellitus ] . - pubmed
In 23 patients with diabetes mellitus , the effectiveness of anesthesiologic support of the operations on the aorta and major vessels , which was based on combined epidural anesthesia performed using the conventional technique , was analysed . - pubmed
Pharmacokinetics of cefprozil in healthy subjects and patients with hepatic impairment . - pubmed
The pharmacokinetics of cefprozil were studied in 12 ( 9 men , 3 women ) subjects with hepatic impairment and in 12 healthy subjects who were matched for age , sex , and weight . - pubmed
The values for the peak plasma concentrations ( Cmax ) , area under the plasma concentration versus time curve ( AUC0 - infinity ) , apparent total body clearance ( Clt / F ) , renal clearance ( Clr ) , and percent of drug excreted in urine ( % UR ) of each isomer were not significantly different in healthy subjects and patients with hepatic impairment . - pubmed
The only parameters that were significantly ( P less than or equal to .05 ) longer in patients with hepatic impairment were mean residence time in the body ( MRT ) and half - life ; the MRT for the cis isomer in healthy subjects and subjects with hepatic impairment were 3.33 hr and 3.88 hr , respectively , and for the trans isomer 3.17 hr and 3.68 hr ; the half - life for the cis isomer was 1.62 hr and 2.22 hr , respectively , and for the trans isomer 1.21 hr and 1.54 hr . - pubmed
The pharmacokinetics of the cis and trans isomers of cefprozil were virtually identical in healthy subjects as well as those with hepatic impairment . - pubmed
The authors retrospectively analyzed 51 morphine - augmented hepatobiliary studies performed in a tertiary referral center on a population with a high proportion of severe intercurrent illness ( 18 patients , 14 of whom were receiving total parenteral nutrition ) and hepatocellular dysfunction ( eight patients ) . - pubmed
Four patients developed recurrent vascular graft thrombosis while receiving anticoagulation . - pubmed
Patients with a chronic risk for arterial or venous thrombosis can have out - patient anticoagulant therapy administered at optimal intensity and regulated safely with a low incidence of hemorrhagic and thrombotic events . - pubmed
All three patients were suffering from malabsorption when TPN was instituted , and overt symptoms of copper deficiency developed an average of 5.8 months after the start of TPN . - pubmed
Numerous metabolic parameters in serum and urine were examined in 110 cataract patients before and after cataract surgery . - pubmed
In addition , an " energetic action " of the light affecting the hypothalamus via the retino - hypothalamic pathways ( the " energetic portion " of the visual pathway ) was proved in patients who were blinded by cataract and had metabolic disturbances as a result . - pubmed
Postoperatively , after elimination of the lens opacities , the metabolism and hormones of the same patients returned to normal . - pubmed
These comparative investigations in the same patients before and after cataract extraction provide for the first time irrefutable scientific evidence of the influence of light via the eye on the human organism . - pubmed
Long - term followup in 1,003 extracorporeal shock wave lithotripsy patients . - pubmed
We evaluated 1,003 patients treated with extracorporeal shock wave lithotripsy after a mean followup of 19.1 months ( range 12 to 26 months ) . - pubmed
Patients with lower caliceal stones had a rate without calculi of only 57.8 per cent . - pubmed
Phaeohyphomycotic cyst caused by a recently described species , Phaeoannellomyces elegans . - pubmed
Eleven patients with ureteric transitional cell tumours were reviewed and conservative management recommended . - pubmed
Smoking habits were analysed in 114 patients with subarachnoid haemorrhage , less than 70 years old , obtained from an epidemiological study . - pubmed
Effects of scheduled food and water deprivation on food intake , water intake and body weight of cage - adapted and cage - naive rats . - pubmed
The first experiment examined the effects of four food - deprivation schedules and four water - deprivation schedules on body weight , food intake and water intake of adult rats over ten days of deprivation and two days of recovery . - pubmed
Bronchial hyperreactivity was confirmed in eleven nonselected patients with chronic respiratory disease during a period of quiescence by inhalative provocation with histamine . - pubmed
After one week 's treatment with ketotifen a protective effect against the histamine - induced bronchospasm was observed in nine patients . - pubmed
The rapid appearance of this protective mechanism was demonstrated both in patients with exogenous and endogenous bronchial asthma and in the three patients with chronic bronchitis . - pubmed
In vivo P - NMR spectroscopy : muscle energy exchange in paramyotonia patients . - pubmed
Using phosphorus nuclear magnetic resonance spectroscopy , we studied the muscle metabolism in four patients with paramyotonia congenita as reflected in the PC / Pi and PC / ATP ratios . - pubmed
Pain in the lower limb was the predominant symptom in forty - eight patients . - pubmed
Reduction of the amount of straight leg - raising by 50 per cent or more , with or without pain in the ipsilateral hip when the asymptomatic limb was lifted ( cross - over pain ) and with or without pain radiating up or down the lower limb when the tibial nerve was pressed in the popliteal fossa ( bowstring discomfort ) , was considered evidence of tension on or irritation of the nerve root and was present in all patients . - pubmed
An anaphylactic reaction occurred in one patient and was treated successfully . - pubmed
One patient had transient weakness of the extensor hallucis longus after injection . - pubmed
The potential role of cats in the epidemiology of Toxoplasma gondii infections . - pubmed
The role of perceived versus actual attack in human physical aggression . - pubmed
[ Evaluation of the excretory function of the liver in patients with rheumatic heart disease and circulatory insufficiency ] . - pubmed
Drug toxicity in the human fetus and newborn child . - pubmed
Adult patients with bacterial infections of the lower respiratory tract were given either cefoperazone or cefamandole in a multicenter clinical study of the clinical and bacteriologic efficacy of cefoperazone . - pubmed
The results of this study indicate that cefoperazone is a safe and effective antibiotic for the treatment of lower respiratory tract infections due to S. - pubmed
aureus , and many gram - negative bacilli , including susceptible strains of P. - pubmed
The problem of human geohelminthoses and the prospects for their biological control . - pubmed
The clinical effectiveness of immunotherapy with the cell wall skeleton of Bacillus Calmette - Guerin was assessed in a study involving 140 consecutive patients with gastric cancer , who were gastrectomized at a single institution from January 1976 through December 1978 . - pubmed
These results emphasize effectiveness of BCG - CWS as an adjuvant immunotherapeutic agent in gastrectomized cancer patients . - pubmed
On the basis of the usual diagnostic criteria , 41 % of the workers had asbestosis . - pubmed
Proper selection of patients for successful penetrating keratoplasty depends on four important factors : ( 1 ) psychosocial factors , including visual need , the conditions under which the patient lives , and the patient 's ability to nurture this tissue over many years ; ( 2 ) the general condition of the eye , including the health of the ocular surface , intraocular pressure , motility , anterior segment anatomy , and vitreoretinal disease ; ( 3 ) the structure of the host cornea -- in terms of its thickness , vascularization , epithelial and stromal integrity , and sensation -- as well as the corneal condition for which the operation is being done ; and ( 4 ) the skills of the ophthalmologist managing the graft , particularly those involved in preoperative patient selection and postoperative graft management , as well as his technical surgical skills . - pubmed
In vitro cytotoxic properties of plasma fractions from uremic patients . - pubmed
Uremic plasma were taken from severe uremic patients ( plasma creat . - pubmed
greater than 0.45 mM / L ) and from hemodialysed ( HD ) patients : plasma from HD patients were obtained at the beginning and end of a dialysis session . - pubmed
The modified tochar epistostomy was performed in 7 children with hypoplasia subjected to urethroplasty . - pubmed
Galactosamine - induced cell death in primary cultures of rat hepatocytes . - pubmed
Chlorpromazine given to intact rats 2 hours after treatment with 400 mg / kg galactosamine prevented the appearance of liver cell necrosis . - pubmed
Biochemical and pathological effects of 8 months of neoadjuvant androgen withdrawal therapy before radical prostatectomy in patients with clinically confined prostate cancer . - pubmed
MATERIALS AND METHODS : We evaluated 50 patients with clinically localized prostate cancer treated by 8 months of reversible androgen ablation before radical prostatectomy . - pubmed
DESIGN / PATIENTS : Thirty untreated patients with acromegaly were compared with 30 healthy adults . - pubmed
In this study we have evaluated psychomotor activity ( PMA ) and passive avoidance behavior ( PAB ) in rats with bilateral neurotoxic lesions in the posterior hypothalamic region ( PHR ) ( L ) , where histaminergic neurons are located , and in sham - operated rats ( S ) , two weeks after neurosurgery . - pubmed
Role of acid and duodenogastric reflux in esophageal mucosal injury : a review of animal and human studies . - pubmed
The role of acid and duodenogastric reflux ( DGR ) in the development of esophageal mucosal injury has been extensively investigated using both animal and human models . - pubmed
Despite some conflicting results , preliminary human studies support the results from the animal data suggesting synergistic damaging effects for both bile and acid in esophageal mucosal injury . - pubmed
Delusions and other manifestations of psychotic behavior are common side effects in Parkinson ' s disease ( PD ) patients chronically treated with dopaminergic drugs . - pubmed
We evaluated the effects of low doses of clozapine on the mental and motor functions in PD patients requiring antipsychotic treatment . - pubmed
Twenty - seven PD patients taking dopaminergic drugs and who had psychotic behavior received clozapine at 12.5 to 75 mg / d. Fifteen patients received clozapine for 1 to 11 months ( mean , 6.8 months ) and seven received it for 12 to 24 months ( mean , 18 months ) . - pubmed
No patient exhibited motor deterioration , and the psychotic features disappeared immediately , allowing discontinuation of clozapine after several months in 10 patients . - pubmed
Fifteen patients are still receiving clozapine and are free of psychiatric symptoms . - pubmed
The clozapine treatment was discontinued after 5 days ( 25 mg / d ) in two patients because of somnolence . - pubmed
No patient developed neutropenia . - pubmed
We report 3 patients in whom intraoperative transesophageal echocardiography was used for precise localization of the fistulous drainage site , selective demonstration of vessels feeding the fistulas , and documentation of abolition of fistulous flow , all without need for cardiopulmonary bypass . - pubmed
The patient 's symptoms resolved quickly , and a repeat venogram 16 hours later showed near - complete resolution of the venous obstruction . - pubmed
Transmetatarsal amputation for infection or gangrene in patients with diabetes mellitus . - pubmed
Immediate effects of lung transplantation on right ventricular morphology and function in patients with variable degrees of pulmonary hypertension . - pubmed
OBJECTIVES : This study sought to determine the immediate effects of lung transplantation on right ventricular morphology and function in patients with variable degrees of pulmonary hypertension and to evaluate these features as potential markers of immediate outcome . - pubmed
BACKGROUND : Selected lung transplant recipients with severe preoperative pulmonary hypertension have previously been shown to have a reduction in right ventricular size and improved function at follow - up evaluation . - pubmed
METHODS : Thirty - two consecutive patients ( mean [ + /- SD ] age 44 + /- 11 years ) were prospectively classified into three groups according to their pretransplantation pulmonary artery systolic pressure : severe pulmonary hypertensive group & gt ; or = 75 mm Hg , intermediate pulmonary hypertensive group 40 to 74 mm Hg and non - pulmonary hypertensive group & lt ; 40 mm Hg . - pubmed
Three patients with severe pulmonary hypertension who had continued depression of right ventricular function after transplantation died in the immediate postoperative period . - pubmed
Effect of pyridoxine and magnesium on stress - induced gastric ulcers in mice selected for low or high blood magnesium levels . - pubmed
OBJECTIVE : The association between attention - deficit hyperactivity disorder ( ADHD ) and cigarette smoking in children and adolescents was evaluated . - pubmed
METHOD : Subjects were 6- to 17 - year - old boys with DSM - III - R ADHD ( n = 128 ) and non - ADHD comparison boys ( n = 109 ) followed prospectively for 4 years into mid - adolescence . - pubmed
Extra- and intracellular localization of advanced glycation end - products in human atherosclerotic lesions . - pubmed
Drug administration in patients with renal insufficiency . - pubmed
The general principles to enhance the safety of drug therapy in patients with renal insufficiency include knowledge of the potential toxicities and interactions of the therapeutic agent , consideration of possible alternatives therapies and individualisation of drug therapy based on patient level of renal function . - pubmed
Although optimisation of the desired therapeutic outcomes are of paramount importance , additional pharmacotherapeutic issues for patients with reduced renal function are the prevention or minimisation of future acute or chronic nephrotoxic insults , as well as the severity and occurrence of adverse effects on other organ systems . - pubmed
Investigations of prophylactic approaches to enhance the safety of these agents in patients with renal insufficiency have yielded inconsistent outcomes . - pubmed
Operations through small incisions are mostly applied to patients with less extensive coronary disease , mostly single - vessel disease . - pubmed
Upper eyelid entropion is a complication of chronic blepharoconjunctivitis which may be easily missed unless careful examination of the lid margin of patients with trichiasis is carried out . - pubmed
They are involved in the regulation of proliferation and differentiation , and activating mutations of these genes are commonly associated with human cancers . - pubmed
Of these patients , we know of 3 ( 0.3 % ) who subsequently developed abscesses as a consequence of dropped stones during the laparoscopic cholecystectomy . - pubmed
One additional patient who underwent prior laparoscopic cholecystectomy at another institution developed late infection as well . - pubmed
RESULTS : All 4 patients developed late purulent abscesses that ultimately required open surgical drainage , and 1 patient developed trocar site " tumor " masses that were secondary to inflammatory tissue around gallstone fragments . - pubmed
DESIGN AND PATIENTS : Sixteen patients with persistent anterior instability after recurrent shoulder dislocations were examined in an open MRI unit ( 0.2 T ) following 0.1 mmol / kg of intravenous gadodiamide . - pubmed
In the present study , diphtheria toxoid was used as a model antigen primarily due to its weak immunological properties as well as to its importance as a future human vaccine for mucosal , particularly nasal immunization . - pubmed
In the present study , we have shown that mono - olein / oleic acid vesicles enhance the immunogenicity of admixed diphtheria toxoid in mice to the same level as Alum adsorbed ( or Freund 's complete adjuvant ) when administered parenterally or nasally . - pubmed
Evolution of insulin resistance in coronary artery disease patients on four different pharmacological therapies . - pubmed
The objective of the study was to examine the evolution of insulin sensitivity in a group of patients with stable coronary artery disease receiving one of four different pharmacological therapies . - pubmed
After 6 months , patients treated with captopril and , to a lesser extent , those treated with diltiazem showed statistically significantly decreased steady state plasma glucose concentrations and increased insulin sensitivity index compared to basal values . - pubmed
Peripheral lymphocytes were isolated from two patients with homozygous familial hypercholesterolemia ( FH ) , one homozygote for the mutation N804 K ( FH(Colmenar ) ) in exon 17 , herein described for the first time , and a compound heterozygote carrying the mutations D280 G and G528V , which determine a transport - defective biochemical phenotype . - pubmed
N of 1 randomised controlled trials of oral ketamine in patients with chronic pain . - pubmed
Anecdotal reports suggest that the general anaesthetic drug ketamine , taken orally in low doses , can give rise to some extra analgesia in patients with refractory neuropathic pain . - pubmed
This study was designed to determine the proportion of patients with chronic neuropathic pain responding to oral ketamine , and then to separate the true treatment effect from non - specific effects by means of an n of 1 randomised controlled trial . - pubmed
Twenty - one patients gave informed consent and completed daily pain diaries and continued on their usual treatments ( drug and non - drug ) for the duration of the study . - pubmed
Twelve patients did not progress to the n of 1 trial because of no benefit and/or intolerable adverse effects ( dizziness , drowsiness etc . ) - pubmed
We conclude that oral ketamine only gave rise to an extra analgesic response in three out of 21 patients with chronic neuropathic pain ( 14 % ) . - pubmed
Possible viral triggers are visited here , including cytomegalovirus in view of increased levels of anti - CMV antibodies in scleroderma , and the remarkable similarities between CMV vasculopathies and scleroderma vascular disease . - pubmed
Anti - tumor promoting effects of sesquiterpenes from Maytenus cuzcoina ( Celastraceae ) . - pubmed
HIV patients are at higher risk of developing hypertension at a younger age than the general population . - pubmed
Through selective cultivation using nylon oligomers as a sole source of carbon and nitrogen , two strains which initially had no metabolic activity for nylon oligomers , Flavobacterium sp . - pubmed
In order to examine the natural history of febrile convulsions occurring after 5 years of age , we studied 44 children in whom febrile convulsions persisted after 5 years of age ( group 1 ) and compared their development of unprovoked seizures with a group of 195 children in whom febrile convulsions occurred before 5 years of age ( group 2 ) . - pubmed
In group 1 , we found a higher percentage of unprovoked seizures than in children with febrile convulsions with onset before 5 years of age ( 18.1 % vs 7.4 % , P & lt ; .05 ) . - pubmed
Our data suggest that children with febrile convulsions after 5 years of age probably must be considered as a group of patients at risk of developing unprovoked seizures . - pubmed
[ Scarlet fever and other infections from Streptococcus pyogenes ] . - pubmed
Computed tomography of pulmonary sarcoid - like granulomas induced by complete Freund 's adjuvant in rats . - pubmed
Intravenous injection of complete Freund 's adjuvant ( CFA ) in rats has been proposed as an experimental model for pulmonary sarcoidosis , but only some animals develop granulomas . - pubmed
Thus , lung computed tomography appears to be a valuable tool for the in vivo evaluation of the pulmonary granulomatous reaction induced by complete Freund 's adjuvant in rats . - pubmed
Asynchronously occurring bilateral mandibular hemorrhagic bone cysts in a patient with idiopathic thrombocytopenic purpura . - pubmed
AIMS : To investigate whether intravascular ultrasound provides additional information regarding the prediction of stent thrombosis , a retrospective multicentre registry was designed to enrol patients with stent thrombosis following stent deployment under ultrasound guidance . - pubmed
METHODS AND RESULTS : A total of 53 patients were enrolled ( mean age 61+/-9 years ) with stable angina ( 43 % ) , unstable angina ( 36 % ) , and post - infarct angina ( 21 % ) who underwent intracoronary stenting . - pubmed
A 2.5 - year - old girl with acute disseminated encephalomyelitis , who developed bilateral symmetrical lesions in the basal ganglion , thalamus , corpus callosum , cerebral subcortical white matter , and cerebellar medulla on brain magnetic resonance imaging is described . - pubmed
No effect of extremely low - frequency magnetic field observed on cell growth or initial response of cell proliferation in human cancer cell lines . - pubmed
We , therefore , exposed the five cell lines ( HL-60 , K-562 , MCF-7 , A-375 , and H4 ) derived from human tumors to a magnetic field for 3 days to investigate the effects on cell growth . - pubmed
DESIGN / METHODS : The infants were aged 25 - 36 weeks of gestation , & lt ; or = 7 days of age , and without sedation or congenital abnormalities . - pubmed
and Acinetobacter lwoffii can be sources of nosocomial infection . - pubmed
Pseudomonas aeruginosa is a potentially serious pathogen and is implicated in the aetiology of otitis externa . - pubmed
Does direct visualization of peripatch areas in beating heart eliminate the risk of residual ventricular septal defect in adult patients ? - pubmed
Varying susceptibility to myocardial infarction among C57BL/6 mice of different genetic background . - pubmed
Genetically manipulated mouse lines are invaluable to investigate the effects of a single gene on sensitivity to ischemia . - pubmed
BACKGROUND : We conducted a phase II study of vinorelbine and cisplatin chemotherapy in non - small cell lung cancer ( NSCLC ) patients who had failed previous chemotherapy , to assess the response and toxicity of this combination chemotherapy . - pubmed
Grade 3 or 4 neutropenia occurred in 40.9 % of the patients , and grade 3 or 4 anemia occurred in 13.6 % of the patients during treatment . - pubmed
Uneventful febrile neutropenia occurred in 1 patient . - pubmed
CONCLUSIONS : Vinorelbine and cisplatin salvage chemotherapy produced a modest anti - tumor response , a mild toxicity profile , and reasonable survival in our elderly NSCLC patients with a poor performance status . - pubmed
This regimen deserves further study in elderly NSCLC patients who have failed previous chemotherapy . - pubmed
[ An experiment of gut barrier function damage following multiple firearm injuries in a porcine model ] . - pubmed
OBJECTIVE : To study the characteristics and pathogenesis of gut barrier damage following multiple firearm injuries in porcine models . - pubmed
METHODS : 24 small pigs were divided into 4 groups ( n = 6 each ): control group(group C ) , group H ( gunshot - induced tangential fracture of parietal bone ) , group L ( gunshot - induced comminuted fracture of bilateral femora ) and group M ( combined group H + L ) . - pubmed
The damage of gut barriers in multiple traumas were more severe than that in one - site trauma , which enhanced the incidence of intestinal endotoxin and bacterial translocation and trend to cause enterogenous infection . - pubmed
The first patient was a 65 - year - old woman in whom a carcinoid tumor of the distal bile duct was incidentally found during an open cholecystectomy for cholecystitis . - pubmed
The second patient was a 27 - year - old man in whom a distal common bile duct carcinoid was incidentally found during orthotopic liver transplantation for sclerosing cholangitis and multiple biliary strictures . - pubmed
On the immunological inhibition of transplantation of a carcinoma of mouse . - pubmed
PARTICIPANTS : 120 adults taking simvastatin or atorvastatin after cardiac surgery or myocardial infarction . - pubmed
OBJECTIVES : To assess survival and long term arch patency rates in a consecutive group of children after extended arch repair for coarctation of the aorta . - pubmed
For assessment of survival patients were divided into three groups : 1 , coarctation alone , n = 104 ; 2 , coarctation and ventricular septal defect , n = 38 ; and 3 , coarctation in association with complex intracardiac anomalies , n = 49 . - pubmed
Arch obstruction recurred in seven of 165 ( 4.2 % ) patients : four of 139 ( 2.9 % ) term and three of 10 ( 30 % ) premature infants ( p & lt ; 0.001 ) . - pubmed
Fructose variation in the dengue vector , Aedes aegypti , during high and low transmission seasons in the Mae Sot region of Thailand . - pubmed
To understand the potential for facultative sugar feeding by Aedes aegypti , an important vector of dengue viruses , we evaluated seasonal and villagewide variation in sugar feeding during high- and low - dengue transmission seasons ( rainy and dry seasons , respectively ) in the Mae Sot region of Thailand . - pubmed
METHODS : Totally 319 patients with hypertension were investigated for their QOL in comparison with 319 healthy controls using the World Health Organization Quality of Life assessment instrument ( WHOQOL-100 ) . - pubmed
CONCLUSION : Improvement of the hypertensive patients ' QOL in addition to effective blood pressure control is a basic target in clinical therapy of hypertension . - pubmed
PARTICIPANTS : Three hundred ninety - seven patients with upper respiratory symptoms of the common cold . - pubmed
CONCLUSION : This homeopathic treatment may be a useful component of an integrated symptomatic therapy for the common cold in patients and practitioners choosing an integrative approach to medical care . - pubmed
BACKGROUND : Chronic hip pain is often a debilitating problem and many patients are not good surgical candidates . - pubmed
METHODS : This is a case series of 4 patients who had anterior and or medial hip pain who underwent percutaneous radiofrequency lesioning of the sensory branches of the obturator and femoral nerves . - pubmed
RESULTS : All four patients had reduction in pain , while 3 of 4 patients had improved functioning . - pubmed
Two of the four patients had decreased use of their pain medication . - pubmed
One of the four patients reported numbness at the hip and there were no other side effects . - pubmed
PATIENTS : Forty - nine adults undergoing bone marrow transplantation for hematologic malignancies or metastatic solid tumors . - pubmed
INTERVENTION : Twenty - four patients received heparin and 25 received lepirudin flushes . - pubmed
After 3 - 4 weeks , all 49 patients received the heparin flushes . - pubmed
CONTEXT : Despite a stage - shift to earlier cancer stages and lower tumor volumes for prostate cancer , pathologically advanced disease is detected at radical prostatectomy in 38 % to 52 % of patients . - pubmed
Patients were 425 men with pathologically advanced prostate cancer who had undergone radical prostatectomy . - pubmed
For metastasis - free survival , 76 ( 35.5 % ) of 214 men in the adjuvant radiotherapy group were diagnosed with metastatic disease or died ( median metastasis - free estimate , 14.7 years ) , compared with 91 ( 43.1 % ) of 211 ( median metastasis - free estimate , 13.2 years ) of those in the observation group ( hazard ratio [ HR ] , 0.75 ; 95 % CI , 0.55 - 1.02 ; P = .06 ) . - pubmed
A 67 year old man presented with new - onset atrial flutter . - pubmed
Effectiveness of arterial embolization procedure in uterine cancer patients . - pubmed
Patients with late stage gynecologic malignancies occasionally develop massive pelvic hemorrhage , and management of the hemorrhage is often difficult . - pubmed
Transcatheter arterial embolization with an absorbable gelatin sponge following the Seldinger method was performed to control hemorrhage in five patients with cancer of the uterine cervix . - pubmed
Pelvic arteriograms of five patients showed no further extravasation and their bleeding ceased . - pubmed
Based on these findings , this therapeutic embolization method proved to be useful in the management of massive pelvic hemorrhage in patients with cervical cancer . - pubmed
OBJECTIVE : To assess the effect of repeated application and removal of adhesive edges from wound - care products on cutaneous irritancy and barrier function in normal volunteer subjects . - pubmed
Adhesive edges from six commonly used wound - care products were applied continuously to the same site ( six applications over a 14 - day period ) in 30 normal volunteer subjects . - pubmed
Most of the research has suggested that these changes , at least in the majority of individuals , occur only at a very advanced stage ; however , those conditions that are treatable and potentially reversible are acute in onset and often associated with acute confusional states . - pubmed
Therefore , physicians should be aware of the possibility of reversible causes of cognitive change in their elderly patients , including certain medications responsible for memory loss and other organ system diseases . - pubmed
In addition , the authors stress that not all memory loss in geriatric patients is due to Alzheimer ' s disease and that when history and physical examination provide evidence of hypertension and magnetic resonance imaging provides evidence of leukoaraiosis , a diagnosis of vascular dementia should be considered . - pubmed
However once diagnosis is made and haematoma removed , it gives good symptomatic relief to the patient . - pubmed
Isolates of Clostridium perfringens type D produce the potent epsilon - toxin ( a CDC / U.S. Department of Agriculture overlap class B select agent ) and are responsible for several economically significant enterotoxemias of domestic livestock . - pubmed
PATIENTS / METHODS : Ten patients with PG were treated with IVIG at Johns Hopkins Department of Dermatology . - pubmed
Five patients complained of nausea with treatment , and in one case nausea was severe and intractable . - pubmed
One patient developed an immune reaction requiring diphenhydramine and methylprednisolone and another experienced aseptic meningitis . - pubmed
Pustular psoriasis - like tinea incognito due to Trichophyton rubrum . - pubmed
We describe an 11 - year - old girl who presented with widespread erythematous and pustular lesions being treated with topical corticosteroid . - pubmed
Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of Escherichia coli C that produce succinate and malate . - pubmed
Pregnancy complications were chronic hypertension in 21 patients ( 40 % ) , anemia in 28 ( 52.6 % ) , and urinary tract infection in 18 ( 34 % ) . - pubmed
Three patients ( 5.6 % ) had graft losses as a result of hemorrhagic shock , sepsis , and eclampsia . - pubmed
Cesarean section was performed in 24 patients ( 45.2 % ) , the main indications being related to hypertension and fetal distress . - pubmed
Effect of trans-2,3 - dimethoxycinnamoyl azide on enhancing antitumor activity of romidepsin on human bladder cancer . - pubmed
A PEG tube for enteral feeding was placed in a 27 - year - old man with cerebral plasty and a severe scoliosis . - pubmed
UNLABELLED : The aim of the present study was to retrospectively re - evaluate a population of selected infants with congenital hypothyroidism ( CH ) , in order to investigate whether sexual dimorphism affects : a ) CH etiology ; b ) its biochemical severity at the time of screening and recall ; c ) patients ' biochemical response to replacement treatment during the 1st yr of life ; d ) their bone maturation ( BM ) at birth ; e ) their psychomotor status at 1 yr . - pubmed
Thirty boys ( 39.5 % ) and 66 girls ( 56.9 % ) were found to have ectopia , whereas the remaining 46 boys and 50 girls exhibited the other causes of CH . - pubmed
Failure to develop multiple sclerosis in patients with neurologic symptoms without objective evidence . - pubmed
BACKGROUND : Many patients referred to multiple sclerosis ( MS ) centers with symptoms suggestive of MS are found to have normal neurologic examinations , normal or non - specific brain magnetic resonance imaging ( MRI ) scan findings , and normal cerebrospinal fluid ( CSF ) . - pubmed
We performed a study to evaluate the diagnostic utility of repeated evaluations in patients with normal initial assessments and persistent neurologic symptoms . - pubmed
No patients at initial presentation or at follow - up fulfilled diagnostic criteria for MS . - pubmed
BACKGROUND : Infection with Helicobacter pylori ( H. - pubmed
These results strongly suggest that HCV infection cured in patients who achieve an SVR . - pubmed
Ischemic cerebrovascular events in patients with Chagas cardiomyopathy : a prospective follow - up study . - pubmed
The aims of this study were to describe the incidence and to evaluate the effect of LV ejection fraction on the risk for ICE in patients with Chagas cardiomyopathy . - pubmed
METHODS : A total of 213 consecutive patients with Chagas disease and LV systolic dysfunction , 131 males , mean age 48+/-12 years , were prospectively enrolled . - pubmed
CONCLUSIONS : In patients with Chagas cardiomyopathy , the annual incidence of ICE is low . - pubmed
Influence of lean body mass on cardiopulmonary repercussions during the six - minute walk test in patients with COPD . - pubmed
The objective of this study was to analyze the cardiopulmonary variables in COPD patients with or without LBM depletion , prior to and after the six - minute walk test ( 6MWT ) . - pubmed
METHODS : We evaluated COPD patients , 32 with LBM depletion and 36 without . - pubmed
All patients underwent clinical evaluation , spirometry , evaluation of body mass composition and 6MWT , as well as completing questionnaires related to quality of life and perception of dyspnea . - pubmed
The distance covered on the 6MWT was similar in COPD patients with and without LBM depletion ( 470.3 + /- 68.5 m vs. 448.2 + /- 89.2 m ) . - pubmed
However , patients with LBM depletion presented significantly greater differences between baseline and final values in terms of heart rate and Borg scale index for lower limb fatigue . - pubmed
However , the patients with LBM depletion presented more pronounced lower limb fatigue during the 6MWT , which underscores the importance of the evaluation and treatment of systemic manifestations in COPD patients . - pubmed
Several animal models have been developed to assist in determining efficacy of immunosuppression in AIED , and several clinical studies have also investigated the role of both steroid and steroid - sparing treatments . - pubmed
Here , the repetitive division pattern of cambial initials in Populus nigra ' italica ' was studied to follow the development of the PD network during maturation . - pubmed
We report a case of a patient who developed DIIHA caused by 2 drugs . - pubmed
In this study , we found that F13 greatly inhibited cell proliferation in various human cancer cells . - pubmed
OBJECTIVE : To determine the incidence of early postoperative complications in patients undergoing cervical spine surgery and its correlation with preoperative diagnosis . - pubmed
METHODS : Patients with supratentorial tumors undergoing elective craniotomy for tumor resection under standard anesthesia underwent cerebral autoregulation and CO2 reactivity testing immediately before and between 6 and 24 hours after surgery . - pubmed
However , cerebral autoregulation was impaired preoperatively in 7 ( 20 % ) patients and remained impaired in all 7 patients after tumor resection . - pubmed
CONCLUSION : Preoperative cerebral autoregulation was impaired in a significant number of patients with large supratentorial tumor size and midline shift more than 5 mm and was associated with postoperative impaired cerebral autoregulation during the first 24 hours after the surgery . - pubmed
Bariatric surgery for type 2 diabetes : weighing the impact for obese patients . - pubmed
Bariatric surgery results in significant weight loss and remission of diabetes in most patients . - pubmed
CLINICAL CASE : We present the cases of two patients with ISCH who were misdiagnosed and operated on in other spinal segments without reaching an accurate diagnosis . - pubmed
Treatment may allow recovery of the neurological deficit , improving motor affection in 80 % of patients and sensory affection in 35 % . - pubmed
MATERIALS AND METHODS : This study was carried out in 30 patients in the age group 10 - 14 years with bilateral carious permanent first molars . - pubmed
The present study investigated whether and how spatial orientation deficits are modulated by external , contextual changes in neglect patients . - pubmed
In a classic rod - and - frame task , we analyzed effects of frame orientation on the subjective visual vertical ( SVV ) in neglect patients , control patients with left- or right - sided brain damage without neglect and healthy participants . - pubmed
We found that neglect patients , but not brain - damaged control patients , generally display a systematic counterclockwise ( CCW ) tilt in their SVV judgments . - pubmed
METHODS : Retrospective case note analysis of 98 patients who underwent early scanning ( between 7 and 28 days ) of their fistula as well as routine scanning at 6 weeks over a 2 - year period . - pubmed
Furthermore , currently adequately powered and optimally designed long - term prostate disease data are not available to determine if there is an additional risk from normal T values in cured patients for PCa . - pubmed
However , the available data suggest to the expert in sexual medicine that TTh can be cautiously considered in selected hypogonadal men previously treated for curative intent of low - risk PCa and without evidence of active disease . - pubmed
Heterochromatin integrity is crucial for genome stability and regulation of gene expression , but the factors involved in mammalian heterochromatin biology are only incompletely understood . - pubmed
CONCLUSIONS : Intraoperative infusion of milrinone did not significantly improve the perioperative hemodynamics and the subsequent short term outcomes for the patients with preexisting diastolic dysfunction as represented by an elevated E / e ' value , although it reduced the degree of decrease of the SvO(2 ) during OPCAB . - pubmed
Institutionalized schizophrenic patients are a high risk group for hepatitis B virus infection . - pubmed
In this study , cytotoxic effects of flavones ( apigenin and luteolin ) on two different cancer cell lines , including human chronic myelogenous erythroleukaemia ( K562 ) and bladder carcinoma ( RT112 ) , were determined , and the molecular mechanisms responsible for their cytotoxic effects were studied . - pubmed
Molecular metabolic fingerprinting approach to investigate the effects of borneol on metabolic alterations in the liver of nitric oxide deficient hypertensive rats . - pubmed
The over all findings demonstrate that in nitric oxide deficient animal model of hypertension , the liver metabolic program is altered through increasing the structural modification in proteins and triglycerides , and quantitative alteration in proteins , lipids , and glycogen . - pubmed
Pial arteriovenous fistulae in pediatric patients : associated syndromes and treatment outcome . - pubmed
The presentation , treatment and syndromes associated with pAVF in children are reported here . - pubmed
Patients with carotid - cavernous fistulae , dural arteriovenous fistulae , brain arteriovenous malformations and vein of Galen malformations were excluded . - pubmed
RESULTS : Between July 2003 and June 2011 , seven patients with pAVF ( six intracranial and one spinal ) were treated . - pubmed
Functional Status Scale scores at the most recent follow - up were 6 in all but one patient who had presented with a pretreatment hemianopsia . - pubmed
CONCLUSION : Treatment is effective in obliterating pAVF in children , with an excellent prognosis seen in our cohort . - pubmed
No patients had hemorrhagic hereditary telangiectasia . - pubmed
The treatment for patients with locally advanced , resectable rectal cancer has evolved over the years . - pubmed
Since FOLFOX ( folinic acid , 5 - FU , and oxaliplatin ) is the preferred adjuvant chemotherapy regimen for stage III colon cancer based on randomized clinical trial results , FOLFOX is also recommended for rectal cancer patients as an adjuvant therapy approach . - pubmed
Epidemiological features of 1 281 patients with head injuries arising from the 2008 Wenchuan earthquake . - pubmed
According to Glasgow Coma Scale score at admission , 1 029 patients presented with mild injury , 161 moderate injury and 91 severe injury . - pubmed
Repeated administration of Ro 19 - 8022 resulted also in an increased sensitivity to convulsant action of pentylenetetrazol in immature rats ( higher incidence and severity of seizures ) . - pubmed
[ Effects of wenhua juanbi recipe on the gene expression profile of the synovium in collagen - induced arthritic rats ] . - pubmed
OBJECTIVE : To study the effects of Wenhua Juanbi recipe ( WJR ) on the gene expression profile of the synovium in collagen - induced arthritis ( CIA ) rats , and to explore its mechanisms for treating CIA . - pubmed
Recent long - term prospective studies have shown that 30 % to 65 % of patients with idiopathic RBD will eventually develop a neurodegenerative disorder with the rate of emergence depending on the length of the follow - up period . - pubmed
METHODS : A retrospective analysis of 20 patients treated for PSP in our department in the last two years was performed . - pubmed
METHODS : In an attempt to examine this hypothesis , we assessed the association of the rs12979860 genotypes with HTLV-1 PvL levels and clinical status in 112 unrelated Brazilian subjects ( 81 HTLV-1 asymptomatic carriers , 24 individuals with HAM / TSP and 7 with Adult T cell Leukemia / Lymphoma ( ATLL ) ) . - pubmed
[ Tamoxifen maintained long - term complete response in an elderly patient with breast cancer ] . - pubmed
At present , 3 months after the operation , our patient is alive with no recurrence . - pubmed
Renoprotective mechanisms of telmisartan on renal injury and inflammation in SHRSP.Z - Leprfa / IzmDmcr rats . - pubmed
BACKGROUND : SHRSP.Z - Lepr(fa)/IzmDmcr ( SHRSP fatty ) rats create a new animal model of metabolic syndrome . - pubmed
RESULTS : Vehicle - treated SHRSP fatty rats developed proteinuria and renal dysfunction , which in the telmisartan group was less than the vehicle and hydralazine group without changing blood pressure . - pubmed
Glomerulosclerosis and interstitial fibrosis were impaired in SHRSP fatty rats , and the renal damage in the telmisartan group was less than the vehicle and hydralazine groups . - pubmed
Nail psoriasis masqueraded by secondary infection with Rhodotorula mucilaginosa . - pubmed
In levodopa - treated patients with motor fluctuations who were already receiving optimized dopaminergic treatment , the addition of rasagiline adjunct therapy significantly improved tremor symptoms . - pubmed
Tremor symptoms also improved in a subset of patients with severe tremor when rasagiline was added to their existing PD treatment regimen . - pubmed
These data suggest that rasagiline used as monotherapy and as adjunctive therapy is effective for reducing tremor severity in patients with PD . - pubmed
MATERIALS AND METHODS : Patients were included if pretreatment MR imaging identifying an intramedullary spinal cord metastasis and an [ ( 18 ) F ] FDG - PET examination near the time of MR imaging were available . - pubmed
RESULTS : The final study sample was 10 PET examinations in 10 patients with 13 intramedullary spinal cord metastases . - pubmed
In 7 ( 70 % ) patients , retrospective blinded review demonstrated convincing evidence of 10 ( 77 % ) intramedullary spinal cord metastases . - pubmed
Intramedullary spinal cord metastasis was confidently reported clinically in 2 ( 20 % ) patients , accounting for 5 ( 38 % ) intramedullary spinal cord metastases . - pubmed
Supplementation with quercetin attenuates 4 - nitrophenol - induced testicular toxicity in adult male mice . - pubmed
The beneficial effects of quercetin on reproductive damage elicited by 4 - nitrophenol ( PNP ) were studied in adult male mice . - pubmed
Taken together , these findings indicated that the antioxidant quercetin displays a potential preventive effect on PNP - induced oxidative damage in mouse testes and may represent an efficient supplement to attenuate reproductive toxicity from environmental toxicants in order to ensure reproductive health and sperm production . - pubmed
A 24 - year - old woman with congenital adrenal hyperplasia ( CAH ) was referred for evaluation of elevated liver enzyme activities over the preceding 6 months . - pubmed
The patient was diagnosed with CAH at the age 12 when she presented with irregular menses and hirsutism . - pubmed
A few studies have shown that patients with CAH often develop metabolic abnormalities and insulin resistance , particularly women treated with glucocorticoid for several years . - pubmed
It is important to be aware that steatohepatitis can develop in these patients due to long - term glucocorticoid use and potentially lead to progressive liver damage . - pubmed
Furthermore , in patients with CAH who develop abnormal liver enzyme activities a liver biopsy is warranted to assess for steatohepatitis and any associated fibrosis . - pubmed
We present a case of GBS in a thirteen years old boy who developed severe tongue weakness and wasting at two weeks after the onset of GBS . - pubmed
Hemodynamic and neuropathological analysis in rats with aluminum trichloride - induced Alzheimer ' s disease . - pubmed
BACKGROUND AND AIMS : Hemodynamic normality is crucial to maintaining the integrity of cerebral vessels and , therefore , preserving the cognitive functions of Alzheimer ' s disease patients . - pubmed
Synchronously , the regional cerebral blood flow ( rCBF ) of the rats with AlCl3 - induced AD were measured using magnetic resonance imaging ( MRI ) . - pubmed
The results also show that the reduction of rCBF in rats with AlCl3 - induced AD was approximately 50 % to 60 % that of normal rats . - pubmed
CONCLUSION : The results accentuate the importance of hemorheology and reinforce the specific association between hemodynamic and neuropathological changes in rats with AlCl3 - induced AD . - pubmed
METHODS : Right heart failure was induced by right coronary artery ligation in a sheep model . - pubmed
Single rapamycin administration induces prolonged downward shift in defended body weight in rats . - pubmed
Instead , RAP animals defended a lower body weight achieved after RAP treatment . - pubmed
METHODS : Forty - seven AEF patients were included in this study . - pubmed
OBJECTIVES : To investigate the efficacy of stretch - and - flow voice therapy as a primary physiological treatment for patients with hyperfunctional voice disorders . - pubmed
METHODS : Participants with a diagnosis of primary muscle tension dysphonia or phonotraumatic lesions due to hyperfunctional vocal behaviors were included . - pubmed
Circulating miR-126 - 3p levels were determined in 136 healthy subjects ( CTRs ) aged 20 - 90 years and 193 patients with type-2 diabetes mellitus ( T2DMs ) aged 40 - 80 years , to explore the combined effect of age and glycemic state on miR-126 - 3p expression . - pubmed
Aging / senescence - associated miR-126 - 3p up - regulation is likely a senescence - associated compensatory mechanism that is blunted when endothelial cells are exposed to high glucose levels , a phenomenon that probably occurs in vivo in T2DM patients . - pubmed
Spatial patterns of structural brain changes in type 2 diabetic patients and their longitudinal progression with intensive control of blood glucose . - pubmed
RESEARCH DESIGN AND METHODS : Using baseline MRIs of 488 participants with type 2 diabetes from the Action to Control Cardiovascular Risk in Diabetes - Memory in Diabetes ( ACCORD - MIND ) study , we applied a new voxel - based analysis methodology to identify spatially specific patterns of gray matter and white matter volume loss related to diabetes duration and HbA1c . - pubmed
RESULTS : Participants with longer diabetes duration had significantly lower gray matter volumes , primarily in certain regions in the frontal and temporal lobes . - pubmed
RESULTS : Out of the 5,352 patients managed during the period , 474 ( 8.9 % ) were blind , 3,178 ( 59.4 % ) had low vision while 1,700 ( 31.7 % ) had " normal vision " . - pubmed
In a single ascending dose study conducted in healthy subjects , JNJ-42847922 increased somnolence and displayed a favorable pharmacokinetic and safety profile for a sedative / hypnotic , thus emerging as a promising candidate for further clinical development for the treatment of insomnia . - pubmed
KEY RESULTS : A resveratrol tetramer , vitisin B from grapevine root extract showed high potency against HCV replication ( EC50 = 6 nM ) with relatively low cytotoxicity ( EC50 & gt;10 muM ) . - pubmed
In this study , 275 patients in use of tenofovir were retrospectively followed - up for three years to evaluate risk factors involved in impaired renal function . - pubmed
Systemic arterial hypertension ( SAH ) and diabetes were found in 20.4 % and 8.7 % of the patients , respectively . - pubmed
TDF was discontinued in 12 patients , one because of a femoral neck fracture ( 0.7 % ) and 11 due to nephrotoxicity ( 4 % ) . - pubmed
Functional Recovery of a Human Neonatal Heart After Severe Myocardial Infarction . - pubmed
Recently , cardiac regeneration has been demonstrated in fish and newborn mice after apex resection or cardiac infarctions . - pubmed
OBJECTIVE : To assess whether human neonatal hearts can functionally recover after myocardial infarction . - pubmed
METHODS AND RESULTS : Here , we report the case of a newborn child having a severe myocardial infarction due to coronary artery occlusion . - pubmed
The child developed massive cardiac damage as defined by serum markers for cardiomyocyte cell death , electrocardiograms , echocardiography , and cardiac angiography . - pubmed
CONCLUSIONS : These data indicate that , similar to neonatal rodents , newborn humans might have the intrinsic capacity to repair myocardial damage and completely recover cardiac function . - pubmed
The evaluation of M - I disposition is important for the pharmacokinetics , pharmacodynamics and toxicity of TAK-475 in animals and humans . - pubmed
In this chapter , we describe : ( 1 ) animal models available for assessing the effect of potential medications on specific aspects of CUD , ( 2 ) the main findings obtained so far with these animal models , ( 3 ) the approaches used to assess potential medications in humans in laboratory experiments and clinical trials , and ( 4 ) the effectiveness of several potential pharmacotherapies on particular aspects of CUD modeled in these human studies . - pubmed
In CPD patients , age , MEM effects on PPI , and rs1337697 predicted sensitivity to the neurocognitive effects of MEM . - pubmed
CSF samples from patients with unruptured aneurysms were used as controls . - pubmed
Link between nasal carriage of Staphylococcus aureus and infected diabetic foot ulcers . - pubmed
AIMS : Nasal carriage of Staphylococcus aureus in diabetic patients may be a risk factor for diabetic foot lesion infections . - pubmed
METHODS : A total of 4000 dogs which had been consecutively scored for canine hip dysplasia were checked for the presence of a LTV . - pubmed
RESULTS : In dogs with an asymmetrical LTV , the hip joint was significantly more predisposed to subluxation and malformation on the side of the intermediate or sacral - like transverse process ( p & lt;0.01 ) , on the side of the elevated pelvis ( p & lt;0.01 ) , or when an asymmetrical LTV resulted in pelvic rotation on its long axis ( p & lt;0.01 ) , whereas hip joint conformation was less affected on the side featuring a free transverse process ( p & lt;0.01 ) . - pubmed
Asymmetrical hip conformation may therefore be the sequela of a LTV and mask or aggravate genetically induced canine hip dysplasia . - pubmed
The impact of influenza varied by subtype and age group across the five seasons with the highest crude cumulative hospitalisation incidence for influenza A / H1N1pdm09 cases in 2010/2011 and in 0 - 4 year olds each season for all - subtypes . - pubmed
Ichthyosis fetalis in a cross - bred lamb . - pubmed
Two congenital forms of ichthyosis are recognized in animals : fetalis ( IF ) and congenita . - pubmed
HYPOTHESIS / OBJECTIVES : To provide clinical , laboratory and pathological assessments of a case of IF in a cross - bred lamb . - pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : This case report describes a case of presumptive ichthyosis fetalis in a lamb . - pubmed
Here , we employed bisulfite DNA - modification assays to analyze the methylation status of the Igkappa locus in primary pre - B cells from RAG - deficient mice with pre - rearranged Igh knock - in allele . - pubmed
INTRODUCTION : The main risk factors for head and neck squamous cell carcinoma ( HNSCC ) are tobacco and alcohol consumption and human papillomavirus ( HPV ) infection . - pubmed
Giardiasis is a treatable disease , caused by the flagellated protozoan parasite , Giardia duodenalis ( G. - pubmed
Recent gene expression profiling has proven successful in predicting the outcome of prostate cancer patients ; however , they have yet to provide targeted therapy approaches that could inhibit a patient 's progression to metastatic disease . - pubmed
Treatment options have been increasingly growing in the past years and newer drugs , some with novel mechanisms of action , are being developed for treating patients with MS . - pubmed
To address this question , we measured human brain activity before and after fear acquisition under conditions of 24 h sleep deprivation versus normal sleep using resting - state functional magnetic resonance imaging ( rs - fMRI ) . - pubmed
Fifty eyes of 50 patients in ARC group and fifty eyes of 50 patients in myopia with cataract group were included . - pubmed
( Lamiaceae ) is native to Southern California and was reportedly used by the Chumash people as a disinfectant and for the treatment of rheumatism . - pubmed
Both proteins are expressed in non - HGPS individuals , and physiological aging shares many features of progeria . - pubmed
BACKGROUND : Hydroxychloroquine ( HCQ ) is a widely prescribed medication to patients with systemic lupus erythematosus ( SLE ) , with potential anti - inflammatory effects . - pubmed
METHODS : In this prospective cohort study , 41 newly diagnosed SLE patients receiving 400 mg HCQ per day were included . - pubmed
Long - term effects of combined percutaneous atrial septal defect occlusion and pulmonary valvuloplasty in children & lt ; 2.5 years old . - pubmed
Effectiveness and cost - effectiveness of neuromuscular exercise and back care counseling in female healthcare workers with recurrent non - specific low back pain : a blinded four - arm randomized controlled trial . - pubmed
METHODS : We randomly assigned female healthcare workers with recurrent non - specific LBP to one of four study - arms : Combined neuromuscular exercise and back care counseling ; Exercise ; Counseling ; and no intervention Control . - pubmed
RESULTS : From 2014 to 2017 , 108 AHI ( 80 first infections , 28 reinfections ) were reported in 96 MSM ( HIV - infected 72 , HIV - negative 24 ) . - pubmed
All clusters included HIV - infected MSM , 6 also included HIV - negative MSM . - pubmed
METHODS : We performed a multicenter , randomized trial of patients with a large nonpedunculated colon polyp ( & gt;=20 mm ) at 18 medical centers in North America and Spain from April 2013 through October 2017 . - pubmed
Postprocedure bleeding occurred in 3.5 % of patients in the clip group and 7.1 % in the control group ( absolute risk difference [ ARD ] 3.6 % ; 95 % confidence interval [ CI ] 0.7%-6.5 % ) . - pubmed
The graft and patient survival and complications were not influenced by the time of transplant for both HCC and non - HCC population . - pubmed
Sacubitril / valsartan for heart failure in adults with complex congenital heart disease . - pubmed
BACKGROUND : Heart failure is an important cause of morbidity and mortality in adults with congenital heart disease ( ACHD ) . - pubmed
METHODS : Retrospective study of ACHD patients with CHD of moderate / severe complexity and heart failure under treatment with sacubitril / valsartan . - pubmed
CONCLUSION : In this small group of complex ACHD patients with heart failure , treatment with sacubitril / valsartan did not improve systemic ventricular function or functional status . - pubmed
Their critical function in heart formation is evidenced by the phenotypes of animal models lacking these factors and by the broad spectrum of human congenital heart diseases associated with mutations in their genes . - pubmed
This in turn will greatly improve diagnosis and care for the millions of individuals affected by congenital and acquired cardiac disease worldwide . - pubmed
A 65 - year - old man underwent high tibial osteotomy after the diagnosis of the right knee osteoarthritis . - pubmed
Markers flanking each QTL were physically mapped against the durum wheat reference sequence and candidate genes involved in disease resistance were identified within the QTL intervals . - pubmed
Transcatheter aortic valve replacement : A potential option for aortic insufficiency management in patients with left ventricular assist device . - pubmed
PATIENT CONCERNS : A 46 - year - old woman with 3 previous vaginal deliveries underwent laparoscopic mesh sacrohysteropexy for stage III uterine prolapse . - pubmed
One month after surgery , the patient developed persistent symptoms , such as stiffness of the lumbosacral portion , low back pain ( LBP ) , persistent swelling , pain between the right iliac crest and the buttock , inability to bend down , and pain in the right lower limb . - pubmed
Lipid abnormalities , including hypertriglyceridemia , are one of the most common comorbidities in patients with chronic kidney disease ( CKD ) and are independently associated with disease progression . - pubmed
A recent clinical study demonstrated that pemafibrate was safe and effective for correcting pro - atherogenic lipid abnormalities in CKD patients with a wide range of renal insufficiency . - pubmed
However , the effect of pemafibrate on renal function in patients with IgAN and hypertriglyceridemia has not been verified . - pubmed
These findings suggest that pemafibrate is safe and effective for correcting hypertriglyceridemia and decreasing urinary protein excretion without changing eGFR and blood pressure levels in mild IgAN patients with hypertriglyceridemia . - pubmed
BACKGROUND : Pain is a common symptom for patients with pancreatic cancer and is often treated using palliative radiation therapy . - pubmed
With the recent advancements in radiation dosimetric planning and delivery , the Juravinski Cancer Centre in Hamilton , Ontario , offers a hypofractionated dose of 2500 cGy in 5 fx for the improvement of pain and tumour control in selected pancreatic cancer patients . - pubmed
METHODS : A retrospective analysis of 24 patients diagnosed with unresectable pancreatic cancer was conducted . - pubmed
CONCLUSION : A palliative radiotherapy dose regime of 2500 cGy/5 fx demonstrates a potential for the effective control of pain with limited acute toxicities in patients with unresectable pancreatic cancer . - pubmed
In this study , we tested its antiviral activity of DENV , JEV and ZIKV , and found that POM-12 dramatically inhibited their infection with IC50 value of 1.16 muM , 1.9 muM and 0.64 muM , respectively . - pubmed
METHODS : In this prospective , monocentric , case series study , consecutive patients who fulfilled the following inclusion criteria benefited from an early postmortem structural brain MRI : death < 24 hours , SARS - CoV-2 detection on nasopharyngeal swab specimen , chest computerized tomographic ( CT ) scan suggestive of COVID-19 , absence of known focal brain lesion , and MRI compatibility . - pubmed
SARS - CoV-2 - related olfactory impairment seems to be limited to olfactory bulbs . - pubmed
We sought to describe the frequency of achievement of therapeutic vancomycin concentrations in critically ill patients receiving ECMO with therapeutic drug monitoring ( TDM ) . - pubmed
In this retrospective observational study , we included all critically ill patients receiving TDM for vancomycin whilst on ECMO . - pubmed
Patients not receiving RRT and those with mild to moderate acute kidney injury ( AKI ) were at a risk of underdosing while those with established AKI on RRT may experience supratherapeutic concentrations . - pubmed
Moreover , PDMS - SB - UU showed a lack of hemolysis and cytotoxicity with whole ovine blood and rat vascular smooth muscle cells ( rSMCs ) , respectively . - pubmed
GM2 ganglioside accumulation causes neuroinflammation and behavioral alterations in a mouse model of early onset Tay - Sachs disease . - pubmed
Although Tay - Sachs patients appear normal at birth , the progressive accumulation of undegraded GM2 gangliosides in neurons leads to death . - pubmed
Progressive accumulation of GM2 led to premature death of the double KO mice . - pubmed
Importantly , this double - deficient mouse model displays typical features of Tay - Sachs patients , such as cytoplasmic vacuolization of nerve cells , deterioration of Purkinje cells , neuronal death , deceleration in movement , ataxia , and tremors . - pubmed
Furthermore , our work contributes to better understanding of the neuropathology in a mouse model of early onset Tay - Sachs disease . - pubmed
Deep sequencing detects human papillomavirus ( HPV ) in cervical cancers negative for HPV by PCR . - pubmed
BACKGROUND : Human papillomavirus ( HPV ) is a necessary cause of cervical cancer , although some invasive cervical cancers may test negative by HPV PCR . - pubmed
CONCLUSIONS : Unbiased deep sequencing provides comprehensive data on HPV types in cervical cancers and appears to be an important tool for quality assurance of HPV screening . - pubmed
Some of the mechanisms of fibrosis development have been described using rodent models ; however , the relevance of findings in these animal models is difficult to assess . - pubmed
METHODS : To overcome this unmet need of investigating IPF with a relevant model , we utilized tree shrews , which are genetically , anatomically , and metabolically similar to primates and humans . - pubmed
Using human antibodies and primers , we investigated the role of macrophage phenotypic switching in normal and IPF subjects and bleomycin - injured tree shrews . - pubmed
CONCLUSION : The profibrotic polarization of macrophages has been demonstrated to be present in IPF subjects and in fibrotic mice . - pubmed
These observations demonstrate that tree shrews are an ideal animal model to investigate the pathogenesis of IPF as they are genetically , anatomically , and metabolically closer to humans than the more commonly used rodent models . - pubmed
Weak anti - SARS - CoV-2 antibody response is associated with mortality in a Swedish cohort of COVID-19 patients in critical care . - pubmed
Quercetin attenuates naso - sinusal inflammation and inflammatory response in lungs and brain on an experimental model of acute rhinosinusitis in rats . - pubmed
This study aimed to investigate the effect of quercetin without intranasal inflammation and oxidative stress in nasal and sinus mucosa , but also in serum , lungs and brain in a rat model of acute nasal and sinus inflammation induced by administration of lipopolysaccharides ( LPS ) ( from Escherichia coli ) . - pubmed
The intranasal LPS administration successfully induced acute rhinosinusitis in a rat model and also generated an inflammatory response in the lungs and brain . - pubmed
Initial response of ovarian tissue transcriptome to vitrification or microwave - assisted dehydration in the domestic cat model . - pubmed
Using the prepubertal domestic cat as a model , the objective was to study immediate effects of vitrification or microwave - assisted dehydration on the global transcriptome dynamics in the ovarian cortex . - pubmed
CONCLUSIONS : Our results showed , for the first time , different effects of vitrification and microwave - assisted dehydration protocols on the global transcriptome of the ovarian cortex ( using the domestic cat as a biomedical model ) . - pubmed
Currently recognized sampling practices for general toxicity studies in animals , which are based on easily discerned external neuroanatomic landmarks and guided by extant stereotaxic brain atlases , typically will permit histopathologic evaluation of many brain centers involved in visual sensation ( eg , optic chiasm , optic tract , dorsal lateral geniculate nucleus , primary and secondary visual cortices ) and often some subcortical brain nuclei involved in light - modulated nonvisual activities needed for visual attention and orientation ( eg , rostral colliculus in quadrupeds , termed the superior colliculus in bipeds ; several cranial nerve nuclei ) . - pubmed
Use of immune repertoire sequencing to resolve discordant microscopic and immunochemical findings in a case of T cell - rich large B cell lymphoma in a young dog . - pubmed
BACKGROUND : Lymphocytic neoplasms with frequent reactive lymphocytes are uncommonly reported in dogs , and can pose a diagnostic challenge . - pubmed
CONCLUSIONS : T cell - rich large B cell lymphoma is a rare neoplasm in dogs that may be challenging to diagnose and classify due to mixed lymphocyte populations . - pubmed
Two long - term therapy trials with high concentrations of antibiotic were carried out to determine the duration of therapy required to achieve bacteriologic cure of experimental Pseudomonas keratitis in guinea pigs . - pubmed
In order to determine the features of early radiologic diagnosis we report the findings of 7 further patients with neonatal septic osteoarthritis with clinical and radiological follow - up . - pubmed
An own case is shown up : There was taken nephrectomy and following local radiation of hypernephroma in a 59 years old male patient in spite of pulmonary metastases . - pubmed
Sensitivity patterns for the induction of homeotic shifts in a favorable strain of mice . - pubmed
Approaching the clinical problems of patients with cerebrovascular disease . - pubmed
Three antimicrobial combinations , ticarcillin plus cephalothin ( T + C ) , ticarcillin plus gentamicin ( T + G ) , and cephalothin plus gentamicin ( C + G ) , were administered to 105 febrile granulocytopenic cancer patients at the Baltimore Cancer Research Center as part of a multi - institutional prospective randomized antibiotic trial . - pubmed
The bactericidal activity of the serum from these 32 patients supplements the overall clinical results of the multi - institutional antibiotic trial and suggests that T+G is a useful initial regimen for empiric therapy of febrile episodes in granulocytopenic cancer patients . - pubmed
[ Biological characteristics of influenza B viruses isolated during influenza B epidemics in 1976 - 1977 ] . - pubmed
Antisera to new B / 76 strains neutralized the hemagglutinating activity of all known reference influenza B virus strains beginning from 1972 . - pubmed
Unlike the Yamagata / 1 / 73 strain , all the influenza B / 76 viruses under study were resistant to thermostable inhibitors of normal horse , guinea pig , and rabbit sera . - pubmed
This response occurred both when body weight gain was used as a measure of intake for pigs nursing on the sow and when intake was measured directly in bottle - fed pigs . - pubmed
Forty consecutive patients underwent flexible fiberoptic transbronchial lung biopsy for diagnosis of diffuse nodular or infiltrative lung disease . - pubmed
In an elderly man bilateral temporal scalp necrosis complicating temporal ( systemic giant cell ) arteritis developed . - pubmed
The patient also demonstrated other features characteristic of this entity : ( 1 ) exquisite scalp tenderness and headache , ( 2 ) onset late in life , ( 3 ) visual disturbances , ( 4 ) general debility , ( 5 ) diagnostic temporal artery biopsy , and ( 6 ) gradual healing with glucocorticosteroid therapy . - pubmed
The mouse rendered eosinophilic by infection with trichinosis provides a suitable model for study of the eosinopenic response induced by acute inflammation . - pubmed
The alterations in eosinophil dynamics associated with acute inflammatory reactions in trichinous mice were studied with pneumococcal abscesses , with Escherichia coli pyelonephritis , with Coxsackie viral pancreatitis , and with acute subcutaneous inflammation due to turpentine . - pubmed
In absence of specific complex therapy , as it was in our experiments , the animals die of shock within the period from 17 min to 5 hour 20 min . - pubmed
[ Effect of coccidial infection on acetylcholine - induced contraction of the digestive tract in chickens . - pubmed
Comparison of infection between Eimeria maxima and E. - pubmed
Excitatory amino acid antagonists and their potential for the treatment of ischaemic brain damage in man . - pubmed
A wide range of therapeutic strategies has been explored in humans and experimental animals with the aim of improving outcome after brain ischaemia but few have shown convincing clinical benefit . - pubmed
This young man was admitted in our hospital because of abdominal pain and hyperamylasemia . - pubmed
The purpose of this retrospective study is to identify prostate cancer patients who would benefit from pelvic nodes irradiation ( whole pelvis ) as opposed to the small - field irradiation to the prostate only . - pubmed
Thus , whole pelvis with prostate boost radiation should be utilized in Stage B and Stage C cancers as this has shown to increase the survival of the patient without increasing chronic radiation morbidity . - pubmed
Auditory evoked response ( AER ) was recorded before , during and after physiotherapy in 11 paralysed ( atracurium 0.56 ( SD ) 0.13 mg kg-1 h-1 ) , sedated ( propofol 2.2 ( 1.0 ) mg kg-1 h-1 ; fentanyl 4.4 ( 2.3 ) micrograms kg-1 h-1 ) and critically ill patients undergoing ventilation in the intensive care unit ( ICU ) . - pubmed
A case of spontaneous trisomy in the spermatocytes of Microtus arvalis . - pubmed
These data suggest that chromosome non - disjunction in premeiotic germ cells can be considered one of the causes of aneuploidy in mammals . - pubmed
Effect of bis ( bilato )- 1,2 - cyclohexanediammineplatinum ( II ) complexes on lung metastasis of B16 - F10 melanoma cells in mice . - pubmed
New platinum ( II ) complexes , bis ( bilato )- 1,2 - cyclohexanediammineplatinum ( II ) which were lipophilic and water - miscible , were tested for antitumor activity against lung nodules from intravenously injected B16 - F10 melanoma cells in C57BL / 6 mice by intravenous administration of the complexes in water suspension form . - pubmed
The authors analyzed a group of 64 children with acute lymphoblastic leukaemia ( ALL ) treated according to three protocols of different intensity . - pubmed
Successful remission in the entire group of patients was 93 % , one third of the children developed during the investigation period a relapse of the basic disease . - pubmed
A quantitative analysis of axon outgrowth , axon loss , and myelination in the rat pyramidal tract . - pubmed
Balloon pulmonary valvuloplasty has been used successfully over the last few years for the relief of moderate to severe valvar pulmonic stenosis in neonates , infants , children , and adults . - pubmed
Campylobacter jejuni is a common cause of acute infectious diarrhoea . - pubmed
Determinants of prognosis in ventricular tachyarrhythmia patients without induced sustained arrhythmias . - pubmed
We studied 59 patients with sustained ventricular tachycardia ( VT ) or ventricular fibrillation in whom programmed stimulation induced 15 or fewer repetitive ventricular complexes . - pubmed
During follow - up of 2.2 + /- 1.5 years , 13 patients had an arrhythmia recurrence and seven died suddenly . - pubmed
Prior myocardial infarction ( MI ) was the only independent predictor of arrhythmia recurrence ( p less than 0.02 ) and sudden death ( p = 0.05 ): at 2 years , 36 + /- 12 % of 18 patients with MI and 8 + /- 4 % of 41 patients without MI had arrhythmia recurrence , and 24 + /- 12 % with MI and 3 + /- 3 % without MI died suddenly . - pubmed
None of the nine patients with greater than or equal to 70 % coronary stenosis but no MI had arrhythmia recurrence after anti - ischemic therapy . - pubmed
Possible arrhythmia - precipitating conditions were present during all arrhythmias in 14 patients , but did not predict freedom from arrhythmia recurrence ( p = 0.52 ) or sudden death ( p = 0.81 ) . - pubmed
The maximum number of induced ventricular complexes did not predict arrhythmia recurrence or sudden death : for patients with 0 to 2 , 3 to 5 , and 6 to 15 induced complexes , the 2 - year incidence of arrhythmia recurrence was 16 + /- 7 % , 15 + /- 10 % , and 18 + /- 10 % ; for sudden death , it was 9 + /- 6 % , 0 + /- 0 % , and 14 + /- 9 % . - pubmed
To determine the sensitivity of arm exercise in detecting coronary artery disease ( CAD ) , 30 patients with angina pectoris performed both arm ergometry and treadmill testing before coronary angiography . - pubmed
Ischemic ST depression ( greater than or equal to 1 mm ) or angina occurred more frequently ( 86 % , 26 patients ) with leg exercise than with arm exercise ( 40 % , 12 patients ) . - pubmed
[ Characteristics of strains of Yersinia pestis isolated in the northeastern part of Brazil ] . - pubmed
Non - specific induction of cytotoxicity in normal human lymphocytes in vitro : studies of mechanism and specificity of the reaction . - pubmed
We have demonstrated autoantibodies to the basement membrane and interstitial collagens in the sera of patients with scleroderma ( systemic sclerosis ) ; ELISA ratios correlate directly with the extent of pulmonary fibrosis in these patients . - pubmed
Postictal seizure inhibition in amygdaloid - kindled cats . - pubmed
The results obtained may be summarized as follows : ( 1 ) kindled generalized convulsions resulted in three consecutive postictal stages before recovery from postictal behavioral depression ; ( 2 ) in bilaterally kindled cats , PSI lasted for 3 - 4 h , which was longer than the postictal behavioral depression ; ( 3 ) no correlation was found between interictal spike frequency and decreased susceptibility to convulsion during PSI ; ( 4 ) the duration of PSI was prolonged significantly after secondary site amygdaloid kindling ; and ( 5 ) such changes were observed greater than 2 weeks after the last secondary site stimulation . - pubmed
The rats fed vitamin C showed no change of body weight whilst the animals fed lard gained in body weight . - pubmed
These have been hospital - based and , as such , inevitably over - represent patients with chronic epilepsy . - pubmed
Investigations ( both hospital and community based ) of patients from the onset of seizures show a much better prognosis , and most patients suffer only a small number of seizures in total over a relatively short period of time and then remit . - pubmed
The traditional view of epilepsy as a chronic condition with a continuing tendency to relapse is therefore not tenable for the majority of patients . - pubmed
The patterns of epilepsy are established relatively early in its course in most cases , and long term prognosis might therefore be predictable within a few years of the onset of seizures in most patients . - pubmed
Arginine vasotocin and aggression in rats . - pubmed
Between 1968 and 1981 52 patients with syringomyelia were investigated clinically and with several additional procedures . - pubmed
From own experiences the following measurements are indicated in patients with presumed syringomyelia : X - rays of the cervical and thoracal spinal column and the skull have to be complemented by automatic computerized transverse axial tomography ( ACTA ) of the spinal canal . - pubmed
Genetic control of resistance to Salmonella typhimurium infection in high and low antibody responder mice . - pubmed
Mice selected by Biozzi for high and low responses to sheep erythrocytes were investigated for resistance to subcutaneous Salmonella typhimurium infection . - pubmed
Analysis of resistance data of backcrosses of ( high x low)F1 with either parental strain showed this genetic control to be at least one other gene in the Biozzi mice , not linked to Ity . - pubmed
To validate the use of 99mTc - PIPIDA in the diagnosis of biliary tract disease , 117 patients with clinical symptoms of acute cholecystitis were prospectively scanned as an initial screening test . - pubmed
Complete common duct obstruction was confirmed at surgery in 12 patients ( 100 % ) . - pubmed
In Experiment 1 , rats suppressed responding to a compound light + tone stimulus that was repeatedly paired with shock . - pubmed
Groups of rats were then presented with only one element of the compound ( the tone ) , either presented alone or paired with shock , for 15 days . - pubmed
Rats that had received the tone paired with shock during the intervening training continued to suppress to the light , whereas rats that had received the tone alone showed rapid extinction of the CER to light . - pubmed
Sulindac ( Clinoril ) was tested in an open clinical - therapeutical study with regard to its analgesic effect and the improvement of function in 20 patients of both sexes suffering from periarthropathy of the hip or shoulder . - pubmed
The therapeutic effect was judged on the basis of the influence on the spontaneous pain and on the pain by pressure , on the functional improvement and on the daily habits of the patients . - pubmed
Eighteen mongrel dogs were divided into two groups : hypoxic control group ( FIO2 = 11 % , n = 10 ) and NO inhalation group ( FIO2 = 11 % , NO inspiratory concentration = 44 ppm , n = 8) . - pubmed
In all three patients , effusion cytology revealed Burkitt ' s lymphoma , characterized by a uniform population of non - cohesive lymphoid cells with noncleaved nuclei , prominent multiple nucleoli , and scanty - to - moderate basophilic cytoplasm . - pubmed
In vivo selection of long terminal repeat alterations in feline leukemia virus - induced thymic lymphomas . - pubmed
To determine what genetic changes are selected in the enhancer sequences of the feline leukemia virus ( FeLV ) long terminal repeat in cats that develop T cell tumors , we cloned proviral U3 sequences in cats that died with thymic lymphoma following infection with molecularly cloned FeLV . - pubmed
Additionally , in clones from two of four cat tumors , portions of the enhancer including Lvb and core were duplicated with respect to the single enhancer unit of the inoculating virus . - pubmed
In contrast , a PCR survey of necropsy DNA samples derived from five cats that did not develop tumors revealed that all retained the single enhancer unit of the infecting virus . - pubmed
These results demonstrate that viruses with duplicated enhancers can be generated and selected after only a single passage in cats , and furthermore , that such viruses may be particularly selected in tumors . - pubmed
CAST patients receiving beta - blocker therapy had significantly enhanced survival at 30 days , and at 1 and 2 years of follow - up against all - cause and arrhythmic death or nonfatal cardiac arrest . - pubmed
In CAST patients with a history of congestive heart failure , beta - blocker therapy was independently associated with longer time to occurrence of new or worsened congestive heart failure ( p = 0.015 ) . - pubmed
Antitumor activity and tissue distribution of bis ( bilato )- 1,2 - cyclohexanediammineplatinum ( II ) complexes in BDF1 mice with murine reticulum cell sarcoma ( M5076 ) . - pubmed
Murine reticulum cell sarcoma ( M5076 ) was subcutaneously implanted into BDF1 mice and then the antitumor activity of seven micelle - forming type platinum complexes was tested . - pubmed
The total Pt levels were significantly higher in tumor tissue from mice given the more active complex than in tumor tissue from mice given the less active complex . - pubmed
The patient presented with sudden onset of left arm pain , shortness of breath , nausea , vomiting , and diaphoresis . - pubmed
Misdiagnosis is common , as it is seen in the same patients at risk for ischemic heart disease , stroke , and other vascular abnormalities . - pubmed
Impairment of intracortical GABAergic inhibition in a rat model of absence epilepsy . - pubmed
The WAG / Rij rat strain is characterized in its EEG by the manifestation of spike - wave discharges which resemble in their spontaneous appearance and pharmacological sensitivity the absence epilepsy observed in humans . - pubmed
In order to test the hypothesis whether cellular intrinsic membrane and/or synaptic network properties in the neocortex are modified in this form of epilepsy , we analyzed with extra- and intracellular recording techniques the functional status of neocortical slices obtained from adult epileptic WAG / Rij rats and compared them with the data acquired from non - epileptic control Wistar rats . - pubmed
Our data indicate that the imbalance between intracortical excitatory and inhibitory mechanisms may at least contribute to the expression and augmentation of spike - wave discharges in epileptic WAG / Rij rats . - pubmed
Sympathetic skin response in parkinsonian patients . - pubmed
Sympathetic skin response ( SSR ) was recorded in 23 patients with idiopathic Parkinson ' s disease ( IPD ) using mechanical as well as electrical stimuli . - pubmed
Central mechanisms might be responsible for these findings and the role of central sympathetic pathway damage in parkinsonian patients is discussed . - pubmed
Physical responses to different modes of interval exercise in patients with chronic heart failure -- application to exercise training . - pubmed
METHOD : In exercise training with chronic heart failure patients , working muscles should be stressed with high intensity stimuli without causing cardiac overstraining . - pubmed
In this study , three interval exercise modes with different ratios of work/ recovery phases ( 30/60 s , 15/60 s and 10/60 s ) and different work rates were compared during cycle ergometer exercise in heart failure patients . - pubmed
It showed high in vitro activity , comparable to those of meropenem and a new carbapenem , BO-2727 , against methicillin - susceptible Staphylococcus aureus and streptococci , with MICs at which 90 % of strains tested are inhibited ( MIC90S ) of & lt ; or = 0.39 microgram / ml . - pubmed
Against members of the family Enterobacteriaceae , Moraxella catarrhalis , and Haemophilus influenzae , ER-35786 inhibited 90 % of strains tested at a concentration of & lt ; or = 1.56 micrograms / ml . - pubmed
The in vivo activity of ER-35786 was highest for systemic infection models with methicillin - resistant S. - pubmed
In acute pneumonia caused by P. - pubmed
Peculiarities of formation of connective tissue framework of granulation tissue and scar were studied using light optical and scanning electron microscopy in rats during all - layer skin wound healing in interscapular region . - pubmed
The response to progressive increases in heart rate to 150 to 160 beats / min by right atrial pacing before and during dobutamine infusion was studied in 3 relatively normal subjects and in 5 patients with severe dilated cardiomyopathy . - pubmed
In patients with heart failure , the heart rate versus LV dP / dt(max ) relations were depressed and flattened without a descending limb . - pubmed
In patients with heart failure , a depressed and flattened relation between heart rate and LV dP / dt(max ) ( force - frequency effect ) did not show the amplification of myocardial contractility by beta - adrenergic stimulation observed in the normal heart . - pubmed
An on - farm study of the epidemiology of Actinobacillus pleuropneumoniae infection in pigs as part of a vaccine efficacy trial . - pubmed
Thirty cohort pigs were followed from birth to slaughter to study epidemiological patterns of porcine pleuropneumonia caused by Actinobacillus pleuropneumoniae . - pubmed
This study is based on 80 children with forearm fractures treated with intramedullary nailing : 64 boys and 16 girls , aged 6 to 16 ( 23 right sides , 58 left sides : 81 fractures ) . - pubmed
Ten children experienced complications , but only complications involving the skin and sepsis were due to the technique . - pubmed
Effect of jiawei shenqi dihuang tang on the content of urinary protein in patients with diabetic nephropathy . - pubmed
The treatment of schizophrenic patients who fail adequate trials of typical neuroleptics is a major challenge . - pubmed
This article provides information on the efficacy of olanzapine for various symptoms of schizophrenic patients and drug safety . - pubmed
Olanzapine is significantly superior to haloperidol in positive , negative , and depressive symptoms of patients , and for tardive dyskinesia and extrapyramidal symptoms . - pubmed
In 3 patients , ischemic lesions demonstrated by the SPECT study was not shown in the MRI study because of motion artifacts . - pubmed
In conclusion , FAIR imagings are considered to be useful in the evaluation of cerebral flow dynamics in the ischemic stroke patients . - pubmed
Our studies demonstrate that the kinetics of cytokine gene expression can reveal additional dysregulation of the immune system in HIV infection , suggesting that PBMC of HIV - infected persons exist in an activated state in vivo that permits them to express cytokine genes more rapidly than a normal PBMC . - pubmed
METHODS : Between 1988 and 1996 , 58 patients were treated with spondylitis or spondylodiscitis . - pubmed
CONCLUSIONS : We recommend surgical treatment on patients with major vertebral body destruction , epidural abscess and progressive neurological impairment . - pubmed
A rod - shaped heliobacterium motile by peritrichous flagella , designated strain OS - H1 , was isolated from a sample of shoreline soil of the soda lake Ostozhe ( pH 9.2 , total salt content 0.22 % ) located in the steppe of south - east Siberia . - pubmed
The G+C content of strain OS - H1 was 45.0 mol% . - pubmed
There is growing concern that the metabolic complications associated with HIV and antiretroviral therapy may lead to accelerated coronary artery disease ( CAD ) . - pubmed
We report a patient with severe varus deformity and tibial shortening caused by dysplasia epiphysealis hemimelica ( DEH ) , a rare skeletal developmental disorder characterized by an osteocartilaginous tumor arising from an epiphysis in young children . - pubmed
We report an uncommon case of unilateral spontaneous hematoma of the right adrenal gland in a 22 - year old young man . - pubmed
Generalized convulsive seizures are often well controlled through classic antiepileptic drugs ( AEDs ) like valproate and clonazepam , whereas myoclonus , the main symptom that is affecting patients most in their daily life , is usually refractory to standard AEDs . - pubmed
A definitive diagnosis could not be made for 5 patients because of lack of histological evidence , but clinical and biological arguments suggested diagnosis of WG . - pubmed
Recently , we have followed up patients with infections caused by MRSA , Pseudomonas aeruginosa and Serratia or carriers of these bacteria , and determined the drug sensitivities of clinical isolates . - pubmed
Platinum - based chemotherapy is the cornerstone of care for patients with metastatic non - small - cell lung cancer ( NSCLC ) . - pubmed
Preclinical and human studies suggest that the orbital frontal cortex and anterior cingulate cortex play an inhibitory role in the regulation of aggression . - pubmed
METHODS : Using positron emission tomography , regional metabolic activity in response to a serotonergic stimulus , meta - chlorophenylpiperazine ( m - CPP ) , was examined in 13 subjects with impulsive aggression and 13 normal controls . - pubmed
CONCLUSIONS : The decreased activation of inhibitory regions in patients with impulsive aggression in response to a serotonergic stimulus may contribute to their difficulty in modulating aggressive impulses . - pubmed
Furthermore , PC(20)FEV(1 ) values in non - asthmatic children with allergic rhinitis ( n = 24 ) were not significantly different from those seen in asymptomatic atopic ( n = 54 ) or non - atopic controls ( n = 92 ) . - pubmed
Therefore , secondary preventive measures in non - asthmatic children with allergic rhinitis ( such as regular local anti - inflammatory therapy or specific immunotherapy ) should be studied and applied more intensely to prevent bronchial hyper - responsiveness ( BHR ) and asthma in this high - risk group . - pubmed
The guidance outlines experimental approaches to evaluating the carcinogenic potential of pharmaceuticals to humans that may obviate the necessity for the routine conduct of two long - term rodent carcinogenicity studies - pubmed
We studied the effects of photosensitizing hypericin in both primary cell cultures and cell lines ( squamous : Kyse-140 and adenocarcinoma : OE-33 ) of human esophageal cancer using an incoherent white light source . - pubmed
High - dose therapy and autologous stem - cell transplantation versus conventional therapy for patients with advanced Hodgkin ' s lymphoma responding to front - line therapy . - pubmed
PURPOSE : To determine whether high - dose therapy ( HDT ) with autologous stem - cell transplantation ( ASCT ) should be included in the initial consolidative treatment of patients with advanced , unfavorable Hodgkin ' s lymphoma ( HL ) . - pubmed
MATERIAL AND METHODS : The analysis of clinical characteristics and course of APSN has covered 24 patients with PAPS ( 16 females and 8 males , mean age 34.3 years ) . - pubmed
RESULTS : PAPS patients developed renal affection in the onset of APS or within the first 5 years of its course . - pubmed
In the majority of patients APSN combined with abnormalities of CNS , heart and skin . - pubmed
[ Motion sickness in animals ] . - pubmed
We investigated in children with attention - deficit - hyperactivity disorder ( ADHD ) the ability to programme and execute goal - directed arm movements . - pubmed
In this condition , the children with ADHD exhibited large end - point errors and prolonged movement durations . - pubmed
Such hyperlactatemic acidosis is particularly marked in lactate - intolerant patients ( shock with lactic acidosis and/or liver disease ) and is particularly strong if high - volume hemofiltration is performed with the associated high lactate load , which overcomes the patient 's metabolic capacity for lactate . - pubmed
METHOD : The Irish Risperidone Olanzapine Drug Outcomes studies in Schizophrenia ( RODOS ) programme was a retrospective review of medical notes and prescription charts in 396 inpatients with schizophrenia or schizoaffective disorder . - pubmed
To address this question , we examined the genetic basis of bony armor loss in three freshwater populations of Alaskan threespine stickleback , Gasterosteus aculeatus , that evolved from fully armored anadromous populations in the last 14,000 years . - pubmed
METHODS : A total of 10 women with adenomyosis ( study group ) and 12 women with uterine myoma ( control group ) were included in this study . - pubmed
Extended phenotypic and genotypic characterization of a limited number ( n=31 ) of isolates from 2002 showed that fusidic acid - resistant strains of S. - pubmed
METHODS : Forty - eight rats were divided randomly into 4 groups : the normal control group , Yin - jaundice model group , Yang - jaundice model group , Yinchen Shufu Decoction treatment group . - pubmed
[ Motor skills and psychiatric disturbances in children ] . - pubmed
RESULTS : More than 40 % of the children examined showed motor deficiency . - pubmed
Psychobehavioral and nutritional predictors of weight loss in obese women treated with sibutramine . - pubmed
OBJECTIVE : To reveal whether baseline body mass index ( BMI ) , and psychobehavioral and nutritional markers were significant predictors of the change in BMI observed after 4 and 12 months in obese women enrolled in a weight reduction program , including low - energy diet , increased physical activity , cognitive behavior therapy and sibutramine . - pubmed
SUBJECTS : In total , 80 obese women ( age : 43.9+/-10.6 y , BMI : 36.7+/-4.8 kg / m(2 ) ) . - pubmed
Variation in recombination rate may bias human genetic disease mapping studies . - pubmed
Previously we have found a functional synergistic interaction after co - administration of gabapentin and B vitamins by using a neuropathic pain model in the rat . - pubmed
In order to evaluate the efficacy of gabapentin and B vitamins in the treatment of diabetic neuropathy in humans we carried out a comparative trial . - pubmed
Both treatments significantly reduced pain and improved quality of life in the patients . - pubmed
Data suggest that the combination of gabapentin and B vitamins could be an alternative treatment for diabetic neuropathic patients . - pubmed
Spectroscopic evidence of cerebral axonopathy in patients with " pure " adrenomyeloneuropathy . - pubmed
OBJECTIVE : To investigate brain involvement in AMN patients with normal MRI , employing multislice MR spectroscopic imaging . - pubmed
METHODS : Twelve men with pure AMN were compared with 19 age - matched healthy volunteers . - pubmed
CONCLUSIONS : ( 1 ) H - MR spectroscopic imaging is able to detect biochemical abnormalities suggestive of axonal damage even in the brains of patients with pure adrenomyeloneuropathy . - pubmed
METHODS : We studied the association between endogenous sex hormones and characteristics of the metabolic syndrome in 400 independently living men between 40 and 80 yr of age in a cross - sectional study . - pubmed
OBJECTIVE : The main objective of the trial was to evaluate the efficacy and tolerance of a three - month pulsed estrogen therapy with intranasal 17 beta - estradiol in patients with menopausal symptoms . - pubmed
The night sweats were observed before the treatment in 90.5 % patients with frequency of 8.8 per week . - pubmed
After 3 and 4 months of treatment the proportion of patients with night sweats decreased to 28.2 % and 11.8 % respectively , and the number of episodes to 2.7 and 2.2 per week ( p & lt ; 0.0005 ) . - pubmed
Osteoporosis can also develop in patients with CKD and ESRD for many reasons beyond age - related bone loss and postmenopausal bone loss . - pubmed
The diagnosis of osteoporosis in patients with severe CKD or end - stage renal disease ( ESRD ) is not as easy to do as it is in patients with postmenopausal osteoporosis ( PMO)--neither fragility fractures nor The World Health Organization bone mineral density criteria can be used to diagnose osteoporosis in this population since all forms of renal bone disease may fracture or have low " T scores " . - pubmed
In patients with stage 5 CKD who are fracturing because of osteoporosis or who are on chronic glucocorticoids , reducing the oral bisphosphonate dosage to half of its usual prescribed dosing for PMO seems reasonable from known bisphosphonate pharmacokinetics , though we do need better scientific data to fully understand bisphosphonate usage in this population . - pubmed
The incidence and severity of seizures increased with time , reaching a peak 7 - 12 h after metaphit administration , and then gradually decreased until 31 h , when no animal responded . - pubmed
Minimum dose which completely blocked seizures in all animals was 0.03 micromole . - pubmed
The present results demonstrate that APH acts as anticonvulsant in metaphit 's model of audiogenic seizures in rats . - pubmed
MATERIALS AND METHODS : Sixty - five patients with gastric cancers were preoperatively examined with MDCT using the water - filling method . - pubmed
Can paroxetine improve well - being in patients with irritable bowel syndrome who do not respond to a high - fiber diet ? - pubmed
We used transgenic mouse models of multistep carcinogenesis to monitor incorporation of bone marrow - derived cells into the neovasculature and to elucidate mechanisms of endothelial precursor cell ( EPC ) recruitment into the tumor microenvironment . - pubmed
Athletes and exercise participants may be at increased risk of ocular , oral , and upper respiratory tract infections . - pubmed
Glycation free adducts accumulate markedly in the plasma of uremic patients and are eliminated in the peritoneal dialysate . - pubmed
Letter regarding article by Weitzman et al , " tobacco smoke exposure is associated with the metabolic syndrome in adolescents " . - pubmed
Quantitative analysis of poliomyelitis - like paralysis in mice induced by a poliovirus replicon . - pubmed
TgPVR21 mice inoculated with TE - PV - Fluc mc showed non - lethal paralysis of the hindlimbs , with severity ranging from a decline in grip strength to complete flaccid paralysis . - pubmed
These results indicate that PV replication in a small population of the motor neurons was critical for severe residual poliomyelitis - like paralysis in TgPVR21 mice . - pubmed
Cardiovascular toxicity due to metoprolol poisoning in a patient with coronary artery disease . - pubmed
RESULTS : Our patient demonstrated findings of AMI with hypotension and bradycardia that appeared to result from metoprolol poisoning . - pubmed
Although one patient has been reported to have AMI associated with metoprolol poisoning , our patient is unique with her ECG changes and elevated cardiac markers : this is the first time that AMI characterized by elevated cardiac markers associated with metoprolol toxicity has been reported . - pubmed
A total of 90 cancerous and non - cancerous tissues from 23 patients with adenocarcinoma and 22 with squamous cell carcinoma were studied . - pubmed
Retinal nerve fibre layer measurements and optic nerve head analysis in multiple sclerosis patients . - pubmed
PURPOSE : To verify whether scanning laser polarimeter with the new variable corneal compensation algorithm ( GDx VCC ) and scanning laser ophthalmoscopy ( Heidelberg Retina Tomograph ( HRT ) ) allow measuring retinal ganglion cell loss in patients with multiple sclerosis ( MS ) . - pubmed
PATIENTS AND METHODS : We enrolled 23 MS patients with a history of previous demyelinating monocular optic neuritis . - pubmed
The Studio Italiano Sugli Effetti Cardiovascolari del Controllo della Pressione Arteriosa Sistolica ( Cardio - Sis ) is a multi - centre study in non - diabetic , treated hypertensive subjects aged & gt;55 years with uncontrolled SBP ( & gt;or=150 mm Hg ) and at least one additional cardiovascular risk factor ( ClinicalTrials.gov identifier : NCT00421863 ) . - pubmed
We investigated the association between familial Mediterranean fever ( FMF ) and osteoporosis ( OP ) in adult patients . - pubmed
Thirty - five attack - free FMF patients ( 28 females , 7 males ; mean age 36.9 + /- 5.7 years ) were individually matched to control subjects on the basis of age ( within 2 years ) and sex . - pubmed
PARTICIPANTS : Ninety - three patients referred with disruptive snoring . - pubmed
INTERPRETATION : The pars plana lensectomy with double - capsule - supported intraocular lens implantation technique seems to be a safe and easy method in children , limiting postoperative IOL - related complications and posterior capsule opacification in the long term . - pubmed
Lamina reclosure that was evaluated with computed tomography , was observed in 4 patients , but no spinal cord compression by the closed laminae was observed . - pubmed
METHOD : Ten patients with chronic stroke ( 7 males ; mean age , 61.4+/-3.02 years ; age range , 48 to 79 years ; mean time since stroke , 28.5 months ; range , 13 to 42 months ) exhibiting stable , affected arm motor deficits were administered mCIT , consisting of : ( 1 ) structured therapy emphasizing affected arm use in functional activities 3 days / week for 10 weeks ; and ( 2 ) less affected arm restraint 5 days / week for 5 hours . - pubmed
We assessed tumor growth and weight in the in vivo nude mice model . - pubmed
On the other hand , stromal cells of TZ suppressed PC-3 cell tumor growth in the mouse model . - pubmed
Interestingly , 20 showed broad cytotoxicity against human cancer cell lines . - pubmed
OBJECTIVE : To summarize the clinical data in preventing HBV recurrence after liver transplantation and explore a optimal individual protocol in prophylaxis of HBV recurrence . - pubmed
METHODS : We retrospected outcomes in 195 recipients who underwent a liver transplantation for HBV - related liver disease between June 2004 and July 2008 . - pubmed
At the sixth and eleventh month after operation , HBV recurrence appeared in 2 recipients , each in two groups , which were due to LAM cessation and HBV mutation respectively . - pubmed
CONCLUSION : Lamivudine combined with HBIg should be considered as a reliable method in preventing HBV recurrence after liver transplantation . - pubmed
METHODS : Human atherosclerotic carotid plaques ( n = 29 , 12 associated with symptoms ) were removed by endarterectomy . - pubmed
These relationships improve understanding of the geographic spread of emerging diseases , and facilitate the development of methods for predicting and preventing epidemics of plants , animals , and humans caused by pathogens that are capable of long - distance dispersal . - pubmed
METHODS : Balb / c mice underwent a weight drop TBI . - pubmed
Selected mice had electrical stimulation of the cervical vagus nerve before TBI . - pubmed
CONCLUSION : In a mouse model of TBI , vagal stimulation prevented TBI - induced intestinal permeability . - pubmed
An 18 - month male infant was admitted to our pediatric emergency service due to poisoning with amitriptyline . - pubmed
The infant 's clinical condition has improved after the charcoal HP , seizures and SVT were not observed . - pubmed
Evaluation of light / dark cycle in anxiety- and depressive - like behaviors after regular treatment with methylphenidate hydrochloride in rats of different ages . - pubmed
In this context , the present study evaluated the effects of treatment with methylphenidate hydrochloride on anxiety- and depressive - like behaviors using young and adult rats during the light and the dark cycle . - pubmed
Clinical presentation and the possible continuous exposure to wheat seem to suggest a case of celiac disease . - pubmed
A 54 - year - old woman presented with blepharoptosis , numbness in the lower lip , dysgeusia and pain in the extremities and back . - pubmed
We performed a meta - analysis of randomized clinical trials using blood pressure - lowering medications , used in patients with hypertension , myocardial infarction , or left ventricular systolic dysfunction , ( n=18 ; 132 854 patients ; 11 988 deaths ) when a second report describing results after the end of the trial was available . - pubmed
Risk factors associated with prevalence of tuberculosis - like lesions and associated mycobacteria in cattle slaughtered at public and export abattoirs in Ethiopia . - pubmed
Urinary excretion of 3 - hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal biotin deficiency in humans . - pubmed
Marginal , asymptomatic biotin deficiency was induced experimentally in the same 10 healthy adults ( 8 women ) by feeding undenatured egg white with meals for 28 d. Biotin status was repleted by a mixed general diet plus biotin supplementation . - pubmed
High susceptibility to Chikungunya virus of Aedes aegypti from the French West Indies and French Guiana . - pubmed
OBJECTIVES : To estimate the vector competence of Aedes aegypti populations sampled from distinct anthropogenic environments in French Guiana , Guadeloupe and Martinique for the strain CHIKV 06.21 . - pubmed
Importantly , studies in the preterm baboon have shown that nephrogenesis is clearly ongoing following preterm birth ; however , the presence of abnormal glomeruli ( up to 18 % in some cases ) is of concern . - pubmed
Small intestinal strangulation caused by a mesodiverticular band and diverticulum on the mesenteric border of the small intestine in a horse . - pubmed
A 4 - year - old Quarter horse stallion was presented for acute abdominal pain . - pubmed
Human respiratory syncytial virus ( RSV ) constitute highly pathogenic virus that cause severe respiratory diseases in newborn , children , elderly and immuno - compromised individuals . - pubmed
Airway inflammation is a critical regulator of disease outcome in RSV infected hosts . - pubmed
The inaugural Translational Science article in this month 's issue is fron Santhiago and colleagues on short - term cell death and inflammation after intracorneal inlay implantation in rabbits . - pubmed
Evaluation of rib microstructure in Wistar rats using SR - muCT after radiation therapy simulation for breast cancer . - pubmed
Treatment outcome of intravenous artesunate in patients with severe malaria in the Netherlands and Belgium . - pubmed
This is the largest case series of artesunate treated patients with severe malaria in Europe . - pubmed
RESULTS : Of the 68 treated patients , including 55 with severe malaria , two patients died ( 2/55 = 3.6 % ) . - pubmed
However , an unusual form of haemolytic anaemia was observed in seven patients . - pubmed
Mother to child transmission of HIV -- another complication of bacterial vaginosis ? - pubmed
Diagnostic performance of P wave duration in the identification of left atrial enlargement in dogs . - pubmed
OBJECTIVES : To determine sensitivity and specificity of P wave duration in the identification of left atrial enlargement in dogs . - pubmed
METHODS : Electrocardiograms from normal dogs and dogs with various cardiovascular diseases were evaluated . - pubmed
CLINICAL SIGNIFICANCE : The diagnostic performance of P wave duration for identification of left atrial enlargement in dogs presents considerable limitations . - pubmed
METHODS : 151 adolescents with T1DM ( mean age 14.9 + - 1.7 years ) and a comparison group ( n = 122 ) reported their depressive symptoms and behavior problems . - pubmed
Differential diagnoses for canine liver disease are commonly based on radiographic estimates of liver size , however little has been published on breed variations . - pubmed
Aims of this study were to describe normal radiographic liver size in Pekingese dogs and to compare normal measurements for this breed with other dog breeds and Pekingese dogs with liver disease . - pubmed
Liver measurements were compared for clinically normal Pekingese ( n = 61 ) , normal non - Pekingese brachycephalic ( n = 45 ) , normal nonbrachycephalic ( n = 71 ) , and Pekingese breed dogs with liver disease ( n = 22 ) . - pubmed
Normal Pekingese dogs had a significantly smaller liver volume / body weight ratio ( 16.73 + - 5.67 , P & lt ; 0.05 ) than normal non - Pekingese brachycephalic breed dogs ( 19.54 + - 5.03 ) and normal nonbrachycephalic breed dogs ( 18.72 + - 6.52 ) . - pubmed
Improved blood pressure control with nifedipine GITS / valsartan combination versus high - dose valsartan monotherapy in mild - to - moderate hypertensive patients from Asia : results from the ADVISE study , a randomized trial . - pubmed
AIMS : ADVISE was a 12 - week , multicenter , randomized , prospective , open - label , parallel - group study comparing combination therapy of nifedipine GITS 30 mg plus valsartan 80 mg ( N + V ) with high - dose valsartan ( 160 mg ) monotherapy ( V160 ) in Asian patients with hypertension . - pubmed
METHODS : Patients with hypertension inadequately controlled with valsartan 80 mg for at least 4 weeks were randomized . - pubmed
Therefore , our zebrafish model provides a powerful in vivo tool for the investigation of tumor - induced angiogenesis , and a cost - effective system for high - throughput screening of anti - angiogenic compounds . - pubmed
In this study , a case of endogenous bacterial endophthalmitis , associated with methicillin - resistant Staphylococcus aureus bacteremia , is presented . - pubmed
METHODS : A total of 11549 subjects were evaluated , and 4951 patients ( 42.8 % ) reported headaches . - pubmed
The 1 - year headache prevalence was 38.6 % in children , 47.0 % in adults , and 23.3 % in the elderly ( p<0.001 ) . - pubmed
The female to male ratio was higher in adults ( p<0.001 ) and elderly headache patients ( p<0.001 ) , but not in children ( p=0.654 ) . - pubmed
Two trials of 30 and 48 hypothyroid women respectively compared levothyroxine doses , but both trials reported only biochemical outcomes . - pubmed
A trial of 169 women compared the trace element selenomethionine ( selenium ) with placebo and no significant differences were seen for either pre - eclampsia ( RR 1.44 ; 95 % CI 0.25 to 8.38 ) or preterm birth ( RR 0.96 ; 95 % CI 0.20 to 4.61 ) . - pubmed
In a controlled randomized clinical trial , 55 patients with chronic tinnitus were randomly divided in two groups . - pubmed
METHODS AND PROCEDURES : Male Wistar rats received ischaemic damage using a transient , focal ischaemia / reperfusion model . - pubmed
Small bowel follow - through ( SBFT ) is a diagnostic tool commonly used in the management of patients with small bowel obstruction ( SBO ) . - pubmed
In this retrospective chart review , 103 patients with the clinical diagnosis of adhesive SBO were evaluated . - pubmed
There were 103 patients with adhesive SBO who met inclusion criteria for this study . - pubmed
Obtaining Gastrografin SBFT in patients with adhesive SBO leads to both a shorter time in identifying the need for operative intervention and to resolution of SBO with nonoperative management . - pubmed
PURPOSE : To evaluate the correlation between different fusional convergence parameters and the Newcastle Control Score ( NCS ) in children with intermittent exotropia . - pubmed
METHODS : In this consecutive prospective observational series , 101 Chinese children with intermittent exotropia were examined by a single observer , who assessed the level of control using the revised NCS and measured the angle of deviation and fusional convergence . - pubmed
CONCLUSIONS : In children with intermittent exotropia , the total convergence amplitude was similar among different levels of control . - pubmed
UNLABELLED : Rhabdomyosarcoma is the most common soft tissue sarcoma in children . - pubmed
Interaction between myelomonocytic and lymphoid cells in a patient with acute myelomonocytic leukemia and chronic lymphocytic leukemia . - pubmed
Medical resource use , costs , and quality of life in patients with acute decompensated heart failure : findings from ASCEND - HF . - pubmed
Because pain , swelling and muscle spasm are complications found in virtually all patients following oral surgery for the removal of impacted teeth , this model has been widely used to evaluate the effects of LLLT on the inflammatory process involving bone and , connective tissue and the muscles involved in mastication . - pubmed
At 2 and 7 days after surgery , the patients will be evaluated by three blinded evaluators who will measure of swelling , mouth opening ( muscle spasm evaluation ) and pain ( using two different pain scales ) . - pubmed
The present study aims to provide a randomized , controlled , double - blind trial to compare four different LLLT parameters in relation to the outcomes of pain , swelling and muscle spasm following surgery for the extraction of impacted third molars and evaluate the effects os surgery on patients ' quality os life ( QOL ) . - pubmed
METHODS : Psychotropic drug use in 196 YOD patients was registered . - pubmed
STUDY OBJECTIVES : The primary objective was to systematically review the literature on how sleep disordered breathing ( SDB ) affects recurrence and death among stroke or transient ischemic attack ( TIA ) patients . - pubmed
METHODS : Adults ( 18 + ) with a stroke or TIA diagnosis were eligible for inclusion . - pubmed
RESULTS : Ten articles covering 1,203 stroke and TIA patients were included in the review . - pubmed
The results generally support a dose - response relationship between severity of SDB and risk of recurrent events and all - cause mortality in stroke and TIA patients . - pubmed
Intolerance to sunitinib treatment in hemodialysis patients with metastatic renal cell carcinoma . - pubmed
However , neither an appropriate dose nor dosing schedule of sunitinib has yet been established for patients with metastatic RCC who are on hemodialysis . - pubmed
Here , we report on two hemodialysis patients who received sunitinib to treat metastatic RCC . - pubmed
Although sunitinib toxicity was manageable in one patient , disease progression occurred after 4 months of treatment . - pubmed
In the second patient , acute pulmonary edema , caused by uncontrolled hypertension , developed on the 15th day of sunitinib therapy and the drug had to be discontinued . - pubmed
[ Transpleural bronchotomy in the treatment of certain foreign bodies in children ] . - pubmed
Sulfated - polysaccharide fraction extracted from red algae Gracilaria birdiae ameliorates trinitrobenzenesulfonic acid - induced colitis in rats . - pubmed
OBJECTIVES : The aim of this study was to evaluate the protective effect of the sulfated - polysaccharide ( PLS ) fraction extracted from the seaweed Gracilaria birdiae in rats with trinitrobenzenesulfonic acid ( TNBS)-induced colitis . - pubmed
METHODS : In the experiments involving TNBS - induced colitis , rats were pretreated with polysaccharide extracted from G. - pubmed
Image diagnosis of zoonotic onchocercosis by Onchocerca lupi . - pubmed
, ultrasound scan , computed tomography and magnetic resonance imaging ) are herein used to diagnose canine onchocercosis in two dogs , which scored positive for O. - pubmed
lupi in dogs and to evaluate the localization of nodules or cysts containing the adult nematode . - pubmed
After percutaneous coronary intervention ( PCI ) including anticoagulation , comatose patients are sedated for mild therapeutic hypothermia . - pubmed
BACKGROUND : Staphylococcus aureus is a leading cause of nosocomial infections . - pubmed
Complement functional tests for monitoring eculizumab treatment in patients with atypical hemolytic uremic syndrome . - pubmed
OBJECTIVES : To optimize eculizumab therapy in aHUS patients by monitoring complement functional tests and markers of disease activity . - pubmed
PATIENTS / METHODS : We studied 18 patients with aHUS ( 10 males ; eight females ; age range , 2 - 40 years ) treated with eculizumab to induce and/or maintain disease remission . - pubmed
gondii strains from sheep and goats slaughtered in East and West Shewa Zones of Oromia Regional State , Central Ethiopia . - pubmed
gondii tissue cysts in sheep and goats slaughtered for human consumption are widespread . - pubmed
RESULTS : Two women and a man presented with of exophthalmos and diplopia . - pubmed
Pain was the most prominent complaint in 2 patients . - pubmed
None of the patients had associated systemic neurofibromatosis by history or examination . - pubmed
CONCLUSIONS : Multiple orbital schwannomas ( primary orbital schwannomatosis ) may be observed in patients without systemic association of neurofibromatosis . - pubmed
Sublethally irradiated NOD / Shi - scidIL2rgamma(null ) mice transplanted with human umbilical cord blood ( HuCB mice ) gradually developed clinical signs of graft - versus - host disease ( GVHD ) such as loss of weight , ruffled fur , and alopecia . - pubmed
Bacterial resistance has been increasingly reported worldwide and is one of the major causes of failure in the treatment of infectious diseases . - pubmed
METHODS : Consecutive patients ( n=18 ) who had undergone successful vitrectomies for idiopathic macular holes were evaluated postoperatively at 1 , 3 , 6 and 9 months . - pubmed
METHODS : This is a descriptive , cross - sectional study on 220 diabetic patients using herbal remedies for perceived glycemic benefit . - pubmed
We examined whether genetic loci previously associated with depressive symptoms predict depressive symptoms among overweight / obese individuals with Type 2 diabetes or change in depressive symptoms during behavioral weight loss . - pubmed
The American Academy of Pediatrics recommends screening children with HTN for sleep disorders because sleep disorders increase the risk for cardiovascular disease . - pubmed
METHODS : Seventy - one patients who underwent arthroscopic suturing of SLAP lesions between July 1995 and May 2008 were evaluated . - pubmed
Associated lesions were seen in 68 of the 71 patients evaluated ( 96 % ) , and the other three ( 4 % ) had SLAP lesions alone . - pubmed
RESULTS : The associated lesions most frequently found in the patients under 40 years of age were labral lesions ( 69 % ) , while in patients aged 40 years or over , impact syndrome with or without rotator cuff injury was the most commonly associated condition ( 71.4 % ) . - pubmed
CONCLUSIONS : There was a great association between SLAP lesions and other shoulder lesions , which varied according to the patients ' age groups . - pubmed
METHODS : Forty PD patients and 40 NC were recruited in this study . - pubmed
MATERIAL AND METHODS : Rapid acquisition with relaxation enhancement , spin echo and gradient echo fast low angle shot data were acquired using ex vivo 3 - Tesla or 7 - Tesla magnetic field strengths from fresh prostatectomy specimens ( n = 15 ) obtained from either organ donor or patients with prostate cancer ( PCa ) . - pubmed
This study reviewed the medical records of 90 patients with lipomas ( 47 patients ) and atypical lipomatous tumors ( ALT)/well - differentiated liposarcomas ( WDL ) ( 43 patients ) of the extremities treated from 2006 to 2012 . - pubmed
All patients had preoperative biopsy and postoperative histologic analysis of the tumors ; surgical margins were marginal in all cases . - pubmed
Local recurrence and metastasis rates and the relationship of patient age and sex with tumor size and location were evaluated . - pubmed
None of the patients with lipomas experienced local recurrence compared with 6 patients ( 13.9 % ) with ALT / WDL who experienced local recurrence within a mean of 48 months ( range , 33 - 96 months ) ; this difference was statistically significant . - pubmed
None of the patients in either group experienced metastasis prior to the study period . - pubmed
Local recurrence did not correlate statistically with patient age or sex , or with tumor size or location . - pubmed
[ Rehmanniae Radix and Rehmanniae Radix Praeparata Ameliorates Renal Interstitial Fibrosis Induced by Unilateral Ureteral Occlusion in Rats and Their Mechanism ] . - pubmed
OBJECTIVE : To study the effects of Rehmanniae Radix and Rehmanniae Radix Praeparata on renal interstitial fibrosis ( RIF ) of obstructed kidneys in a unilateral ureteral obstruction ( UUO ) rat model and the mechanism . - pubmed
MATERIALS AND METHODS : A total of 92 patients with confirmed diagnosis of CCHF in 2009 - 2013 were included in the study . - pubmed
Metformin , a well - known anti - diabetic agent , is very effective in lowering blood glucose in patients with type 2 diabetes with minimal side - effects . - pubmed
However , since metformin is eliminated unchanged through the kidneys and some studies have shown the incidence of lactic acidosis with its use during severe renal dysfunction , the use of metformin was contraindicated in patients with renal disease until recently . - pubmed
With more studies indicating the relatively low incidence of lactic acidosis and revealing the additional benefits with metformin therapy , the US FDA has now approved metformin to be administered in patients with established renal disease based on their renal function . - pubmed
The purpose of this review is to highlight the various mechanisms by which metformin protects renal cells that have lost its functionality in a diabetic or non - diabetic setting and to enlighten the advantages and therapeutic potential of metformin as a nephroprotectant for patients with diabetic nephropathy and other non - diabetic forms of chronic kidney disease . - pubmed
Therefore , we have investigated here whether and how CA would prevent paraquat ( PQ)-induced inflammation - related alterations in human neuroblastoma SH - SY5Y cells . - pubmed
CASE : Five years ago , a 12 - year - old patient underwent linear lens extraction , posterior capsulotomy , and anterior vitrectomy due to traumatic cataract and received a polymethyl methacrylate ( PMMA ) biconvex posterior chamber IOL implanted in ciliary sulcus . - pubmed
Genome - wide DNA methylation analysis during non - alcoholic steatohepatitis - related multistage hepatocarcinogenesis : comparison with hepatitis virus - related carcinogenesis . - pubmed
Principal component analysis using the 3331 probes revealed distinct DNA methylation profiles of NASH - N samples that were different from those of NLT samples and 37 samples of non - cancerous liver tissue showing chronic hepatitis or cirrhosis associated with hepatitis B virus ( HBV ) or hepatitis C virus ( HCV ) infection ( viral - N ) . - pubmed
We aimed to investigate whether sigma-1 antagonism reduces inflammatory pain through the disinhibition of the endogenous opioidergic system in mice . - pubmed
The selective sigma-1 antagonists BD-1063 and S1RA abolished mechanical and thermal hyperalgesia in mice with carrageenan - induced acute ( 3 h ) inflammation . - pubmed
These technologies provide tools for treating the many forms of amyloid disease , restoring organ function and enhancing patient survival . - pubmed
Human papillomavirus ( HPV ) testing is increasingly being incorporated into cervical cancer screening . - pubmed
Cerebral mycotic aneurysms secondary to Streptococcus Agalactiae induced infective endocarditis . - pubmed
Streptococcus agalactiae , is a rare cause of endocarditis and there are no reported cases of cerebral mycotic aneurysms secondary to this organism . - pubmed
We report a rare case of streptococcus agalctiae induced intracranial mycotic aneurysm . - pubmed
Introduction : We report on a rare case of a man with bowel rupture due to direct trauma to his diagnosed inguinal hernia , with reviewing the relevant literature , we have found some characteristics of our case different from the similar cases reported by other authors . - pubmed
Presentation of the case : A 54 - year - old man , with a dignosed right inguinal hernia without treatment for over six months , presented to our hospital with generalized peritonitis and possible sepsis , caused by minimal hit directly to his hernia . - pubmed
Maternal imprinting on cognition markers of wild type and transgenic Alzheimer ' s disease model mice . - pubmed
The risk of suffering from Alzheimer ' s disease ( AD ) is higher in individuals from AD - affected mothers . - pubmed
The purpose of this investigation was to study whether maternal transmission might produce AD - related alterations in progenies of mice that do not have any genotypic alteration . - pubmed
Platelet - rich plasma on female androgenetic alopecia : Tested on 10 patients . - pubmed
AIMS : Investigate the efficacy , tolerability , and clinical improvement of PRP for the treatment of female AGA . - pubmed
PATIENTS / METHODS : A total of 10 female patients affected by AGA and not responding to treatment with minoxidil and/or oral antiandrogens were enrolled . - pubmed
Children and youth are disproportionally affected by concussion , and once injured , take longer to recover . - pubmed
Safety of dose - reduced pemetrexed in patients with renal insufficiency . - pubmed
In this population , renal insufficiency is common ; however , pemetrexed is not recommended in patients with a creatinine clearance ( CrCl ) & lt ; 45 ml / min due to increased myelosuppression reported in phase I trials . - pubmed
METHODS : This is a retrospective case series describing the incidence of grade 3 or higher toxicity in patients with CrCl & lt ; 45 ml / min treated with dose - reduced pemetrexed at The James Cancer Hospital and Solove Research Institute at The Ohio State University . - pubmed
Four ( 22 % ) patients had grade & gt;= 3 hematologic toxicity ; three of which were receiving concomitant platinum agents . - pubmed
No patients receiving single - agent pemetrexed with a CrCl & gt ; 30 ml / min experienced grade & gt;= 3 hematologic toxicity . - pubmed
Folded extended vertical lower trapezius island myocutaneous flaps ( TIMFs ) were created to repair large PCFs that developed after salvage total laryngectomy in eight patients . - pubmed
After 6 - 24months of follow - up , six patients showed no evidence of disease , one was alive with disease , and one had died of local recurrence at 20months . - pubmed
Polyclonal antibodies to Paracoccidioides brasiliensis are able to recognise antigens from different strains from Paracoccidioides species complex , including Paracoccidioides lutzii LDR2 . - pubmed
Since the new species Paracoccidioides lutzii emerged in 2009 , much has been researched on strains previously considered atypical . - pubmed
brasiliensis Pb18 ; ( c)IB and ELISA with a pool of PCM patients ' sera before and after treatment with sodium metaperiodate ( SMP ) to oxidise carbohydrate epitopes . - pubmed
A total of 263 PV strains were isolated , including 22 strains of type 1 PV , 104 strains of type 2 PV , and 137 strains of type 3 PV . - pubmed
As a result of intratypic differentiation , using real - time PCR and nucleotide sequencing , 3 type 1 pre - VDPV , one type 2 VDPV , and 2 type 3 pre - VDPV strains were isolated . - pubmed
Transcatheter closure and conservative management has been described for select patients with iatrogenic fistulas in recent literature . - pubmed
The TGD - treated rats had lower rates of AF inducibility and shorter AF durations than the MI rats . - pubmed
RESULTS : A total of 109 patients ( mean age 64 years , range 19 - 85 ; 66 % male , 38 % never smokers ) referred to our center with features suggestive of ILD underwent cTBB . - pubmed
CONCLUSIONS : In the real - world setting , cTBB has a meaningful diagnostic value in the context of a MDT approach and may enable histopathological assessment even in patients with more advanced disease unsuitable for SLB . - pubmed
Delayed ACL Reconstruction in Patients & gt;=40 Years of Age Is Associated With Increased Risk of Medial Meniscal Injury at 1 Year . - pubmed
PURPOSE : : To evaluate whether delayed reconstruction in a cohort of patients aged & gt;=40 years is associated with an increased risk of meniscal or chondral injury . - pubmed
Medial , lateral , and patellofemoral compartment chondral injury was reported in 127 , 82 , and 130 patients , respectively . - pubmed
CONCLUSION : : Delayed ACL reconstruction ( & gt;=90 days ) among patients aged & gt;=40 years was not associated with an increased risk of meniscal or chondral injury . - pubmed
Impact of atrial fibrillation on in - hospital mortality of ischemic stroke patients and identification of promoting factors of atrial thrombi - Results from the German nationwide inpatient sample and a single - center retrospective cohort . - pubmed
We aimed to investigate the impact of AF on in - hospital mortality of ischemic stroke patients and to identify parameters associated with intra - cardiac thrombogenic material . - pubmed
The inheritance of resistance to the foliar phase of bacterial blight disease , caused by Xanthomonas axonopodis pv . - pubmed
The other occurred in a 25 - year - old patient , was 18 cm wide , and was diagnosed as a well - differentiated neuroendocrine tumor , World Health Organization grade 3 . - pubmed
MAIN BODY : Evidences of the impact of climate change are available for malaria , arbovirus diseases such as dengue , and many other parasitic and viral diseases such as Rift Valley Fever , Japanese encephalitis , human African trypanosomiasis and leishmaniasis . - pubmed
CONCLUSIONS : In this paper we discuss the current state of the results and draw on evidences from malaria , dengue and other vector - borne diseases to illustrate the state of current thinking and outline the need for further research to inform our predictions and response . - pubmed
Thrombocytopenia is commonly seen in patients receiving linezolid for & gt;14 days . - pubmed
Given the dynamics of platelet production and destruction , these results may explain why oxazolidinone - induced thrombocytopenia emerges as one of the most frequent untoward effects in patients exposed to these antibiotics . - pubmed
A 41 - year - old woman presented with a recurrence of myxoinflammatory fibroblastic sarcoma on the medial part of the left foot dorsum . - pubmed
Gut Microbial Metabolite Trimethylamine N - Oxide Is Related to Thrombus Formation in Atrial Fibrillation Patients . - pubmed
Patients with AF are prone to forming cardiac thrombi . - pubmed
No previous studies have examined the relationship between serum TMAO levels and thrombus formation in AF patients . - pubmed
MATERIALS AND METHODS : A total of 117 consecutive rheumatic heart disease patients with AF were enrolled . - pubmed
The patients were divided into 2 groups : patients with thrombi ( n = 25 ) and patients without thrombi ( n = 92 ) . - pubmed
CONCLUSIONS : Elevated serum TMAO levels were predictive of thrombus formation in AF patients . - pubmed
Our results highlight the usefulness of serum TMAO levels in identifying individuals with increased susceptibility to thrombus formation , allowing development of precise thrombus prevention strategies . - pubmed
Cytomegalovirus ( CMV ) is one of the major human health threats worldwide , especially for immunologically comprised patients . - pubmed
The etiology of brain diseases associated with human CMV ( HCMV ) infections is usually complex and it is particularly difficult to treat because HCMV has a life - long infection in its hosts , high mutation rate , and latent infections . - pubmed
For the treatment of glioblastoma , vaccine therapy through targeting specific CMV antigens has improved patients ' survival outcomes significantly and immunotherapy has also emerged as an alternative modality . - pubmed
The advanced research for developing anti - CMV agents and approaches is promising to obtain significant outcomes and expecting to have a great impact on the therapy of brain diseases associated with CMV infections . - pubmed
METHODS : The WAIS - III profiles of 50 adults with ADHD were compared to an age - matched typical development ( TD ) group . - pubmed
All patients with NOA who underwent TESE during their fertility treatments were included . - pubmed
The development of gradient - boosted trees ( GBTs ) aimed to predict the presence or absence of spermatozoa in patients with NOA . - pubmed
OBJECTIVE : To determine the diagnostic accuracy of the CPOT in critically ill patients , a systematic review of diagnostic studies was performed . - pubmed
SETTING : Fuwai Hospital , National Center for Cardiovascular Disease , Beijing , China PARTICIPANTS : Consecutive patients with successfully recanalised CTO were included from January 2010 to December 2013 . - pubmed
CONCLUSION : Patients with long CTO lesion did not show a higher risk of death and MI after recanalisation , but had higher risks of TLR and TVR . - pubmed
The Effect and Optimal Dosage of Dexmedetomidine Plus Sufentanil for Postoperative Analgesia in Elderly Patients With Postoperative Delirium and Early Postoperative Cognitive Dysfunction : A Single - Center , Prospective , Randomized , Double - Blind , Controlled Trial . - pubmed
Background : Postoperative delirium ( POD ) and postoperative cognitive dysfunction ( POCD ) are common complications after major surgery among elderly patients . - pubmed
Dexmedetomidine ( DEX ) is less frequently explored for its effects in patients with postoperative neurocognitive disorders . - pubmed
This study investigated the effect and optimal dosage of DEX for patient - controlled analgesia ( PCA ) on POD and early POCD after major surgery among elderly patients . - pubmed
Compared with DEX 200 mug , DEX 400 mug reduced early POCD in patients who underwent open surgery ( P < 0.05 ) . - pubmed
Compared with DEX 200 mug , DEX 400 mug was preferred for reducing early POCD in patients who underwent open surgery . - pubmed
Evaluation of quality of life in patients surgically treated for potentially malignant oral lesions . - pubmed
This study aimed to evaluate the postoperative QOL of surgically treated patients for OPMDs . - pubmed
Materials and Methods : It was a cross - sectional study done on 45 follow - up patients , aged 24 - 80 years , who were surgically treated for OPMDs . - pubmed
Importantly , 20 % to 30 % of mice were even long - term protected and did never develop clinical signs of tumor growth . - pubmed
CONCLUSIONS : Tumor cell senescence may explain why patients responding to immune checkpoint blockade frequently show stable growth arrest of tumors rather than complete tumor regression . - pubmed
The clinical severity , rapid transmission and human losses due to coronavirus disease 2019 ( Covid-19 ) have led the World Health Organization to declare it a pandemic . - pubmed
Relationship of diffusion tensor imaging parameters with neurocognitive dysfunction in patients with Behcet ' s disease . - pubmed
Thirty - five adults with Behcet ' s disease and 21 age - matched healthy controls were enrolled in this study . - pubmed
The incidence of gastro - intestinal carcinomas in man is rather high as compared to other organ systems ; results of cytostatic or x - ray therapy of these tumors , however , on the other hand are rather poor . - pubmed
Controlled prospective clinical studies are needed in the future in order to elucidate the role of additional cytostatic therapy in patients with malignant tumors of the gastro - intestinal tract . - pubmed
Electroencephalographic and behavioral study of the cat 's reactivity to stimuli during the evolution of cobalt amygdaloid epilepsy . - pubmed
Experimental chronic polyarthritis in mice . - pubmed
For 53 patients with toxic recurrent goiter ( TRG ) , the interval between thyroidectomy and recurrent hyperthyroidism range from six months to 50 years ( average , 12.4 + /- 11.9 years ) . - pubmed
Recurrent hyperthyroidism may occur in older patients for whom cardiac decompensation may be the initial manifestation . - pubmed
Reports on surgically treated hyperthyroid patients may underestimate the incidence of TRG unless follow - up is extended for many years . - pubmed
Seven patients had clinically benign , asymptomatic lesions measuring less than 2 cm in diameter that were devoid of necrosis . - pubmed
The eighth patient had a symptomatic , partially necrotic CCTL 4.5 cm in diameter that metastasized to the liver and peritoneum ; the patient died of tumor 17 years after diagnosis . - pubmed
Cardiac arrest and resuscitation alters the pharmacokinetics of MK-801 in the rat . - pubmed
The therapeutic diagnostic level is shown for this type of iatrogenic impotence and the various therapeutic possibilities are pointed out in relation to the wishes of the patient and to his life expectancies . - pubmed
Ticarcillin- and tobramycin - resistant strains of Pseudomonas aeruginosa were shown to have a markedly increased sensitivity to antibiotics enclosed in liposomes . - pubmed
A long - term follow - up study of maxillary clefts operated on primarily with the maxillary periosteal flap ( 67 patients ) and the free tibial periosteal graft ( 23 patients ) showed a definite bone bridge in 64 versus 85 percent of the patients . - pubmed
Coronary angioplasty was used without surgical back - up in eight patients with angina refractory to medical therapy . - pubmed
Cytotoxic action of adenosine nucleoside and dialdehyde analogues on murine neuroblastoma in tissue culture : structure - activity relationships . - pubmed
A series of purine nucleoside and dialdehyde analogues was studied to determine their potency as inhibitors of C-1300 murine neuroblastoma cell growth in tissue culture . - pubmed
Nasomaxillary fibrosarcomas in three young horses . - pubmed
Nasomaxillary fibrosarcoma was diagnosed in 3 young horses . - pubmed
Selective nephroangiography in the dog causing renal platelet aggregation and irregular nephrographic phase . - pubmed
These effects were followed by tubular damage , which was demonstrated in 4 of 6 dogs examined 48 hours after injection . - pubmed
Formation of thrombi was not demonstrated in 6 dogs given small single doses , which produced a homogeneous nephrographic phase . - pubmed
Uptake of radiopharmaceutical was markedly abnormal in all phases of the bone scan in the feet of patients with diabetic neuropathy . - pubmed
Bone scans were performed in three groups of patients ; diabetics with neuropathic osteoarthropathy ( Charcot joints ) ; diabetics with neuropathy but no evidence of osteoarthropathy and non - diabetic controls . - pubmed
Uptake was monitored in three phases ; during the first 2 min after injection , then at 4 min and finally at 4 h. Uptake in all three phases was markedly increased in the neuropathic subjects , not only in those with osteoarthropathy but also in those with no radiological abnormalities . - pubmed
[ Development of protoscolices of echinococcus multilocularis in experimentally infected mice in dependence on age and sex of the experimental animals and on infection --prerequisites for the development of a test model ] . - pubmed
Long - term methylphenidate treatment of hyperkinetic children . - pubmed
The test revealed a significant increase in titre of antibodies in patients with the allergic or mycetomal forms of pulmonary aspergillosis . - pubmed
[ Level of histamine in peripheral blood in patients with bacterial shock ] . - pubmed
Slow reacting substance in the exudate of allergic air pouch inflammation in rats . - pubmed
The activity of slow reacting substance was examined in the exudate of the allergic inflammation in rats after partial purification by alkaline decomposition and XAD-8 anion - exchange column chromatography . - pubmed
The distributions of platelet volume and density were measured in 15 men suffering myocardial infarction and in 22 healthy controls . - pubmed
Octanol / water partition coefficients were determined and the antimicrobial activity assessed as the minimum growth inhibitory concentrations towards twelve strains of micro - organisms , representative of Gram - negative and Gram - positive bacteria , yeasts and fungi . - pubmed
Since fetal decapitation in the pig hardly influences ovarian development , pituitary dependency of the fetal ovary in the pig is unlikely . - pubmed
Two children with apparent brain abscesses were cured with antibiotic therapy . - pubmed
The clinical application of the different tumor markers for early diagnosis , staging and therapy control of lung cancer patients is described . - pubmed
A patient with a carcinoid syndrome due to liver metastases is described . - pubmed
Continuous negative external chest pressure decreases transvascular lung water transport in sheep after Pseudomonas bacteremia . - pubmed
We studied the effects of continuous negative external chest pressure ( CNECP ) produced by a cuirass appliance on lung water and protein transport in sheep with chronic lung lymphatic fistulas . - pubmed
We conclude that CNECP mechanically reversed the PVPD in our group III sheep . - pubmed
These physiologic effects of CNECP may be of benefit in the management of patients with adult respiratory distress syndrome . - pubmed
PATIENTS AND METHODS : In 70 ( 56 % ) of 125 examined patients with central retinal vein occlusion laser treatment was performed . - pubmed
After laser treatment 3 ( 9 % ) patients with ischemic CRVO developed iris neovascularization and 2 ( 6 % ) neovascular glaucoma . - pubmed
CONCLUSIONS : The results of this study indicate that there is no significant visual improvement in patients with CRVO after laser treatment . - pubmed
We describe three patients with four thumbs in which scapho - trapezoid osteoarthritis was associated with basal joint arthritis . - pubmed
In the other patients , the scapho - trapezoid joint was excised primarily , with resolution of the pain . - pubmed
We describe a case of a severe Cushing syndrome developed in a 51 - year - old man . - pubmed
Although the treatment with SMS-201 - 995 octreotide was effective in controlling the clinical symptoms , the patient died three months later with extensive metastases . - pubmed
DNA - damaging potency and genotoxicity of aflatoxin M1 in somatic cells in vivo of Drosophila melanogaster . - pubmed
Metabolism of serotonin was studied in pineal gland of Wistar rats with low and high rate of audio excitability as well as in the Krushinsky - Molodkina rat population genetically predisposed to audio - dependent convulsions . - pubmed
Intensive turnover of serotonin via N - acetyl serotonin into melatonin was found in pineal gland of rats insensitive to sensory stimulus , whereas the rate of this response was decreased in the gland tissue of animals sensitive to audio effects as well as inhibition of serotonin turnover into melatonin was noticed in pineal gland of rats predisposed genetically to audio - dependent convulsions . - pubmed
[ Genomic changes in strains of the tick - borne encephalitis virus as a result of passages in mice ] . - pubmed
Changes in genomes of TBE strains isolated from various sources at early stages of laboratory adaptation to white mice brain were demonstrated by molecular hybridization of nucleic acids with synthetic oligonucleotide probes , complementary RNA sites of reference TBE strains Sofyin and Neudorf . - pubmed
Of the 4 TBE strains passed 6 times through white mice brain in only 1 the level of RNA hybridization with 2 oligonucleotide probes was found changed , whereas in all the 3 tested strains the level of RNA hybridization with 1 - 2 oligonucleotide probes complementary to strain Sofyin was increased after 7 - 16 passages in the same system . - pubmed
METHODS : Bone mineral density ( gm / cm2 ) at the lumbar vertebrae ( L1 - L4 ) and at the left femur ( neck , trochanter , intertrochanter , and Ward 's triangle ) was measured by dual x - ray absorptiometry in 46 SLE patients ( mean age 31 years , mean disease duration 76 months ) and in 108 healthy female controls ( mean age 32 years ) . - pubmed
Twenty - three Danish clinical strains from 23 patients phenotypically identified to the A. - pubmed
Five strains were allocated to DNA group 2 ( A. - pubmed
These four strains represent two new DNA groups within the A. - pubmed
A comparison of tumor and normal tissue microvascular hematocrits and red cell fluxes in a rat window chamber model . - pubmed
This laboratory has previously used a window chamber model to measure red blood cell velocity in mammary tumors and normal granulation tissues of the F-344 rat . - pubmed
packed cells were injected intravenously into rats bearing an 8 to 10 day old R-3230 mammary carcinoma . - pubmed
STUDY DESIGN : Forty - three patients with symptoms related to uterine enlargement of & lt ; 280 g who underwent total abdominal hysterectomy were compared to 73 patients with uteri weighing & gt ; or = 280 g. RESULTS : The mean age , parity , duration of disease and incident of past myomectomy were not different . - pubmed
The effectiveness of a health education programme for prevention of alcohol abuse and tobacco smoking among adolescents was assessed by an intervention study with a non - randomized control group . - pubmed
The health education programme included the prevention of alcohol abuse in the first school year ( 1989 - 90 ) and the prevention of tobacco smoking in the second year ( 1990 - 91 ) . - pubmed
Case report : the MRI diagnosis of bone marrow infarction in a child with leukaemia . - pubmed
A double - blind , cross - over study was conducted with hypertensive patients following a moderately salt - restricted diet . - pubmed
After a 1 - month run - in period , 13 males and three females with mild to moderate essential hypertension ( mean age 50 years ) complied with a salt - reduced diet . - pubmed
It is concluded that moderate salt restriction seems not to adversely influence insulin resistance or serum lipids in hypertensive patients . - pubmed
We report a man who developed selenium - deficient myopathy during long - term parenteral nutrition . - pubmed
Campylobacter jejuni and Campylobacter coli are common causes of gastroenteritis in humans . - pubmed
Infection with C. - pubmed
Antibodies to this peptide immunolocalized to the zona pellucida of both marmoset and human ovarian sections and inhibited human sperm - zona binding by approximately 60 % in vitro . - pubmed
In fact , the model will be a useful tool to investigate in detail , the pathological mechanisms of the human inner ear disease associated with Vogt - Koyanagi - Harada disease . - pubmed
Staphylococcus hyicus is considered to be an etiological agent of exudative epidermitis in young pigs , but is frequently isolated from chickens and cows . - pubmed
Spontaneous variability of cardiac output in ventilated critically ill patients . - pubmed
PATIENTS : A total of 22 hemodynamically stable acute respiratory failure patients with a pulmonary artery catheter inserted for hemodynamic monitoring INTERVENTIONS : After being sedated , patients were randomized ultimately to receive pressure control ventilation first at setting A ( high positive end - expiratory pressure [ 15 cm H2O ] with conventional I : E ratio [ 1:2 ] ) and then at setting B ( low positive end - expiratory pressure [ 5 cm H2O ] with inverse I : E ratio [ 2:1 ] ) , or vice versa , and then at setting C ( low positive end - expiratory pressure [ 5 cm H2O ] with conventional I : E ratio [ 1:2 ] ) . - pubmed
CONCLUSIONS : In critically ill sedated medical intensive care unit patients with stable hemodynamics , the spontaneous variability of cardiac output over time was not significant . - pubmed
METHODS : Seven hundred sixty - three patients underwent an operation for renal cell carcinoma between July 1989 and January 1999 . - pubmed
Patients with papillary renal cell carcinoma were at increased risk of developing bladder cancer ( standardized incidence ratio [ SIR ] 6.5 , P = 0.038 ) . - pubmed
CONCLUSIONS : There is an increased risk of subsequent bladder and prostate cancer in patients with papillary renal cell carcinoma . - pubmed
Patients were divided into patients with depression / mania onset before 40 and after 40 . - pubmed
There were significant differences between the treatment and control groups , with regard to the number of patients who still had headache after 14 days ( 5 vs. 25 , respectively ; P=.00004 ) , the median length of time until complete disappearance of headache ( 5 vs. 13 days , respectively ; P=.00000 ) , and the number of patients who had repeat lumbar puncture ( 7 vs. 22 , respectively ; P=.002 ) . - pubmed
These results indicate that a 2 - week course of prednisolone was beneficial in relieving headache in patients with eosinophilic meningitis . - pubmed
[ Multilocular fixed drug reaction simulating intertrigo in a diabetic patient ] . - pubmed
HISTORY AND CLINICAL FINDINGS : A 57 - year - old man with diabetes and hypertension was treated with amoxycillin , clarithromycin and pantoprazole for a gastric ulcer positive for Helicobacter pylori . - pubmed
The patient was issued with an " allergic to penicillin " card . - pubmed
CONCLUSION : Intertriginous changes during antibiotic treatment may not be due to Candida intertrigo , which is fairly common , but to a prognostically much more important drug reaction . - pubmed
There was a significant increase in infections caused by methicillin - resistant S aureus ( P = .0001 ) and vancomycin - resistant enterococci ( P = .04 ) over time . - pubmed
Nausea and vomiting continue to rank as important side effects for cancer patients receiving chemotherapy . - pubmed
Herpes simplex virus evolved to use the human defense mechanisms to establish a lifelong infection in neurons -- a review and hypothesis . - pubmed
Based on these studies a hypothesis is presented suggesting that HSV evolved to use the human host defense systems ( pain signals , the immune system cells and sensory neurons ) to ensure its entry from the skin epithelium into the sensory neurons . - pubmed
PATIENTS AND METHODS : In this open study , 38 patients ( 25 men and 13 women , age 19 - 68 ) with chronic hepatitis B virus infection ( HBsAg , HBeAg and p - DNA HBV positive ) were treated with LAM ( 150 mg daily ) for 48 weeks . - pubmed
All were negative for HCV or HDV coinfection and had no decompensated liver disease . - pubmed
The absence of side effects during lamivudine therapy is of special importance especially in patients with advanced liver fibrosis . - pubmed
Pharmacokinetics of ropivacaine in uremic and nonuremic patients after axillary brachial plexus block . - pubmed
Reports on the efficacy and pharmacokinetics of local anesthetics in uremic patients have been controversial . - pubmed
Our study involved 29 uremic and 28 nonuremic patients . - pubmed
Plasma clearance of ropivacaine was smaller and the area under the concentration - time curve of ropivacaine , 3 - hydroxyropivacaine , and PPX larger in the uremic patients . - pubmed
The plasma concentration of PPX increased until 24 h in uremic patients whose AAG concentrations were also larger throughout the study . - pubmed
The free fraction of ropivacaine in plasma was smaller in the uremic group when measured 60 min and 12 h after the block , but the unbound concentration of ropivacaine was larger in the uremic group at 12 h. Enhanced absorption of ropivacaine into circulation , increased binding to AAG , and probably reduced urinary excretion of the metabolites lead to larger total plasma concentrations of ropivacaine and its main metabolites in uremic patients . - pubmed
Gene profiling and promoter reporter assays : novel tools for comparing the biological effects of botanical extracts on human prostate cancer cells and understanding their mechanisms of action . - pubmed
The use of botanical mixtures is commonplace in patients with prostate cancer , yet the majority of these products have not been rigorously tested in clinical trials . - pubmed
Here we use PC - SPES , a combination of eight herbs that has been shown to be effective in clinical trials in patients with prostate cancer , as a model system to demonstrate ' proof of principle ' as to how gene expression profiling coupled with promoter assays can evaluate the effect of herbal cocktails on human prostate cancer . - pubmed
Our data suggest that gene expression profiles of LNCaP human prostate cancer cells in response to PC - SPES are different from those found when diethylstilbestrol ( DES ) , a synthetic estrogen , is used , suggesting that the estrogenic moieties within PC - SPES do not drive this expression signature . - pubmed
Influenza and parainfluenza viruses as well as RS virus affect frequently respiratory tract . - pubmed
Viruses of viral hepatitis B , C , D and HIV , CMV , EBV may be the source of nosocomial viral infections transmitted by blood ( transfusions ) . - pubmed
[ Details concerning benign acute histiocytopathy in children ] . - pubmed
In search of better outcome predictors for patients following resection of colorectal metastases . - pubmed
Orotic acid - induced fatty liver disease was investigated at the transcriptional and metabolic levels using microarrays and metabolic profiling in two strains of rats . - pubmed
Importance of aggressive evaluation in patients with Staphylococcus aureus bacteremia . - pubmed
Previously , we had shown that T cells accumulated in peribronchiolar and perivascular areas of lungs soon after intranasal infection with Streptococcus pneumoniae . - pubmed
We investigated whether the " ornithophilous " floral syndrome exhibited in an African sugarbush , Protea roupelliae ( Proteaceae ) , reflects ecological specialization for bird - pollination . - pubmed
The predatory mite Typhlodromus pyri ( Acari : Phytoseiidae ) causes feeding scars on leaves and fruits of apple . - pubmed
pyri females cause microscopic scars on apple leaves . - pubmed
The present laboratory experiments were carried out to confirm the production of scars on apple leaves and to assess if females cause scars on fruits as well . - pubmed
Scar production on apple leaves and/or fruits was investigated under various nutritional conditions : no food , pollen of Scots pine ( Pinus sylvsestris L. ) only , nymphs of P. - pubmed
Whether the scars produced on leaves and fruits harm the quality of fruits or the yield of apple can not be concluded from the present experiments . - pubmed
Chronotherapy provides a means of individualizing treatment of hypertension according to the circadian profile of blood pressure of each patient . - pubmed
Pseudoaneurysm of the femoral artery in a HIV - infected man . - pubmed
Rat leprosy ; susceptibility of the black mouse ( American race ) to the Stefamsky bacillus . - pubmed
In this study , effect of gadolinium , a synthetic Kupffer cell suppressant , on the reperfusion injury was examined using a canine partial liver transplantation model . - pubmed
Tobacco use was more prevalent in the OR group ( 78.4 % versus 64.2 % ; P = .013 ) , and known carotid artery disease was more prevalent in the EVAR group ( 20.0 % versus 6.9 % ; P = .003 ) . - pubmed
To this aim , we have developed a mouse model of transverse aortic coarctation ( TAC ) between the two carotid arteries , which imposes acutely on the right brain hemisphere a dramatic increase in blood pressure . - pubmed
Eradication of Pseudomonas aeruginosa in cystic fibrosis . - pubmed
, like poultry and cattle , reptiles have emerged as a significant source of human salmonellae infections during the last years . - pubmed
Neurologists need to recognize , diagnose , and treat obstructive sleep apnea ( OSA ) in patients with stroke or transient ischemic attack ( TIA ) . - pubmed
Hypertension or ischemic heart disease usually develops in untreated patients with OSA over time without particular worsening of OSA . - pubmed
Herein , we report a 48 - year - old woman with a history of an incomplete excised nonchondroid pulmonary hamartoma presenting as an indolent tumor recurrence . - pubmed
CASE REPORT : We report the case of a 43 - year - old woman , who presented a chronic autonomic failure , which had begun by symptomatic orthostatic hypotension . - pubmed
MATERIAL AND METHODS : Prospective evaluation of 21 patients ( 15 males , 6 females , 43 - 80 y ) with diffuse lung diseases who underwent clinical work - up inclusive laboratory tests , lung - function tests and transbronchial biopsy . - pubmed
CONCLUSION : Highfield MRI of the lung is feasible and performed slightly better compared to CT in the determination of activity in patients with interstitial lung diseases . - pubmed
Severe pulmonary hypertension occurred in the postoperative period in two patients , and two patients had heart failure following a previous operation for coarctation or interruption of the aorta . - pubmed
The frequency of this allele in 305 blood donors , 90 patients with systemic lupus erythematosus and 234 patients with the systemic inflammatory response syndrome ( SIRS ) and/or sepsis was 0.03 , 0.017 and 0.03 respectively . - pubmed
PURPOSE : To assess the role of radiotherapy ( RT ) in women with Stage IIIC endometrial cancer . - pubmed
METHODS AND MATERIALS : The 17 - registry Survival , Epidemiology , and End Results ( SEER ) database was searched for patients with lymph node - positive non - Stage IV epithelial endometrial cancer diagnosed and treated between 1988 and 1998 . - pubmed
RESULTS : The therapy data revealed 611 women with Stage IIIC endometrial cancer during this period . - pubmed
Of the 611 patients , 293 had organ - confined Stage IIIC endometrial cancer and 318 patients had Stage IIIC endometrial cancer with direct extension of the primary tumor . - pubmed
In patients with organ - confined Stage IIIC endometrial cancer , the 5 - year OS rate was 50 % for NAT , 64 % for EBRT , and 67 % for EBRT / BT . - pubmed
In patients with Stage IIIC endometrial cancer and direct tumor extension , the 5 - year OS rate was 34 % for NAT , 47 % for EBRT , and 63 % for EBRT / BT . - pubmed
CONCLUSION : Women with Stage IIIC endometrial cancer receiving adjuvant EBRT and EBRT / BT had improved OS compared with patients receiving NAT . - pubmed
MicroRNA expression profile in granulocytes from primary myelofibrosis patients . - pubmed
OBJECTIVE : Expression profiling of microRNA ( miRNA ) was performed in granulocytes isolated from patients with primary myelofibrosis ( PMF ) , with the aim of identifying abnormally expressed miRNAs in comparison with normal subjects or patients with polycythemia vera ( PV ) or essential thrombocythemia ( ET ) . - pubmed
Chronic hepatitis B and C viruses ( HBV and HCV ) are common problems in renal transplant patients . - pubmed
Solid pseudopapillary neoplasm of the pancreas : distinct patterns of onset , diagnosis , and prognosis for male versus female patients . - pubmed
METHODS : The medical records of 34 consecutive patients with pancreatic solid pseudopapillary neoplasms between 1990 and 2006 were reviewed . - pubmed
Tumor size tended to be smaller in patients treated in more recent years . - pubmed
Median hospital stay was 11 days , morbidity rate was 62 % , including 17 patients with grade A pancreatic fistula , and there was no operative mortality . - pubmed
Tumor recurred in 2 patients ( 6 % ) . - pubmed
At the time of diagnosis , age was ( x + /- SD ) higher among male patients ( 25 + /- 2 years vs 37 + /- 7 years ; P & lt;.05 ) with no difference in tumor size . - pubmed
UNLABELLED : The obese patients adhere weakly to rehabilitation programs ; therefore the expected gains are often disappointing . - pubmed
MATERIALS AND METHODS : Twenty obese women were recruited . - pubmed
To determine the preferred walk modality , 10 obese women performed a constant velocity walk and an intermittent walk ( with a similar duration and velocity ) on a treadmill . - pubmed
CONCLUSION : The obese patients preferred similarly the constant velocity walk and the intermittent walk , and a rehabilitation program based on an intermittent walk is effective in avoiding the obesity aggravation . - pubmed
This pooled risk estimate was marginally higher than the risk of a false - negative sentinel lymph node biopsy examination ( ie , 7%-8 % ) but marginally lower than the risk of non - sentinel lymph node metastases in patients with micrometastases ( ie , approximately 20 % ) who are currently eligible for an axillary lymph node dissection . - pubmed
Because 36 ( 64 % ) of the 56 patients with isolated tumor cells in their sentinel lymph node also had non - sentinel lymph node macrometastases , those patients with isolated tumor cells in the sentinel lymph node without other indications for adjuvant systemic therapy might be candidates for axillary lymph node dissection . - pubmed
In addition , supplementary administration of vitamin K2 analogues to HCC patients has led to reduce serum DCP levels . - pubmed
In contrast , among reproductively nonphotoperiodic laboratory strains of rats and mice , bulbectomy unmasks reproductive responses to photoperiod . - pubmed
A group of 32 prepubertal children with idiopathic short stature ( ISS ) were included in the study . - pubmed
PATIENTS AND METHODS : Epidemiologic data of patients diagnosed with an autoimmune bullous disease during this time period were registered and statistically evaluated . - pubmed
RESULTS : During the study period , 41 patients with an autoimmune bullous disease were diagnosed , including 27 with bullous pemphigoid , 4 with pemphigoid gestationis and mucous membrane pemphigoid , 2 with dermatitis herpetiformis and linear IgA disease , and 1 with epidermolysis bullosa acquisita and pemphigus vulgaris , respectively . - pubmed
Patients with mucous membrane pemphigoid were found to have the highest mean age at disease onset ( 76 years ) followed by patients with bullous pemphigoid ( 74 years ) . - pubmed
PURPOSE : To compare the ability to delineate and detect patterns of choroidal neovascularization ( CNV ) activity in patients with exudative age - related macular degeneration ( AMD ) after ranibizumab treatment between time - domain optical coherence tomography ( TD - OCT ) and 4 different spectral - domain optical coherence tomography ( SD - OCT ) devices . - pubmed
PARTICIPANTS : Sixty - one eyes of 58 patients with exudative AMD after ranibizumab treatment were included in this study . - pubmed
CONCLUSIONS : SD - OCT is superior to TD - OCT in evaluating for CNV activity in patients with wet AMD after ranibizumab injection . - pubmed
This study investigated whether such image registration can also improve the quality of contrast - enhanced magnetic resonance angiography ( MRA ) in patients with peripheral arterial disease of the lower extremities . - pubmed
In the spirit of Freud 's invitation to other investigators to elaborate on his " Notes Upon a Case of Obsessional Neurosis " ( 1909 ) , the author offers additional and differing views on the case of the Rat Man ( Dr. Ernst Langer ) . - pubmed
METHODS : The Tumor Registry of the Prince of Wales Cancer Centre was audited for patients with an initial diagnosis of squamous / nonsquamous cell NPC who had primary treatment with radiotherapy , and now presented for retreatment . - pubmed
MP , in contrast to other smokeless tobacco variants , seems to cause mucosal changes , which may transform into oral cancer . - pubmed
Melamine ( MEL ) has been involved in several food recalls after the discovery of severe kidney damages in children and pets poisoned by melamine - adulterated food . - pubmed
The authors present the case of an 81 - year - old patient with severe aortic stenosis who experienced left ventricular embolization of an aortic bioprosthesis during transapical aortic valve implantation . - pubmed
The intent of this study was to assess reproductive inhibition and toxicity of emamectin benzoate on H. - pubmed
We further show that podocyte - specific knockdown and systemic short interfering RNA injection confers resistance to podocyte injury in mouse models of nephrosis . - pubmed
Parkinsonism can be psychogenic , and psychogenic parkinsonism is about 10 % of psychogenic movement disorder patients . - pubmed
Patients can present with any feature or combination of features of organic Parkinson ' s disease . - pubmed
Patients may have both organic Parkinson ' s disease and psychogenic parkinsonism , and this might be considered a psychologically induced aggravation of the organic disorder . - pubmed
PURPOSE : To evaluate the role of cryopexy or laser therapy versus observation for management of accidental globe perforation during strabismus surgery in an experimental animal model . - pubmed
CONCLUSIONS : Vision - threatening consequences of globe perforation during strabismus surgery were uncommon in this rabbit model . - pubmed
Mathematical models describing the transmission of dengue viruses have focussed on the so - called antibody - dependent enhancement ( ADE ) effect and temporary cross - immunity trying to explain the irregular behavior of dengue epidemics by analyzing available data . - pubmed
We evaluated whether antiretroviral drugs affected the response to pegylated interferon plus ribavirin in patients co - infected with HIV and hepatitis C virus ( HCV ) . - pubmed
SCOPE : To evaluate the ability of grape skin and seeds to protect endothelial progenitor cells ( EPC ) from oxidative stress induced by hyperglycemia ( HG ) compared to red wine ( RW ) and prepare innovative pharmaceutical systems for the oral administration of red grape extract allowing the overcoming of its poor intestinal absorption . - pubmed
CONCLUSIONS : Red grape components are a source of antioxidant compounds that ameliorate EPC viability and function , while preventing endothelial dysfunction . - pubmed
P301L mice : possible implication for neurodegenerative diseases . - pubmed
P301L mice suffer upper airways defects related to tauopathy within the Kolliker - Fuse nucleus that controls upper airways function . - pubmed
P301L mice triggered precocious upper airways defects and tauopathy in several brainstem nuclei , including the nucleus ambiguus that contains upper airways motor neurons and the Kolliker - Fuse . - pubmed
Sirolimus in addition to a CNI is successful in reversing inflammation in LT recipients with PTAH . - pubmed
Suppression of plasma estrogen levels by letrozole and anastrozole is related to body mass index in patients with breast cancer . - pubmed
CONCLUSION : The suppressed levels of plasma estradiol and estrone sulfate in postmenopausal women with early ER - positive breast cancer treated with the AIs anastrozole and letrozole are related to BMI . - pubmed
Study : shingles vaccine safe for patients on immune - suppressing drugs . - pubmed
A 57 - year - old man presented with blurred vision associated with photophobia and halos around lights . - pubmed
BACKGROUND : Omalizumab has been shown to decrease the risk of hospitalization or ED visits in patients with uncontrolled severe allergic asthma compared with placebo . - pubmed
METHODS : A cohort of adult patients with uncontrolled severe asthma despite optimal treatment with inhaled and oral corticosteroids and a long - acting b 2 -agonist but no treatment with omalizumab upon entry was assembled . - pubmed
Systemic administration of CART has been found to ameliorate dopaminergic neuronal loss and improve motor functions in a mouse model of PD . - pubmed
Differences of aortic stiffness and aortic intima - media thickness according to the type of initial presentation in patients with ischemic stroke . - pubmed
METHODS : A total of 500 patients with acute stroke were divided into 2 groups : the TIA group ( n = 230 , 62.4 + - 12 years , 144 males ) versus CI group ( n = 270 , 63.4 + - 11 years , 181 males ) . - pubmed
RESULTS : After the patient underwent a lung - sparing wedge resection of the pulmonary right upper lobe metastasis and intraoperative brachytherapy with ( 131 ) Cs seeds to a total dose of 80 Gy , she remained disease free in the implanted area . - pubmed
Fifty - nine at - risk infants were enrolled , together with 1:1 matched healthy controls , and stratified by disease severity ( n=25 , HIE ; n=34 , non - HIE PA ) . - pubmed
Gulls were reported as sources of fecal pollution in coastal environments and potential vectors of human infections . - pubmed
Minocycline modulates neuroprotective effect of hesperidin against quinolinic acid induced Huntington ' s disease like symptoms in rats : behavioral , biochemical , cellular and histological evidences . - pubmed
In light of emerging role of flavonoids in modulating oxidative stress and neuro - inflammation , the study has been designed to explore the possible neuroprotective effect of hesperidin and its combination with minocycline ( microglial inhibitor ) , against quinolinic acid ( QA ) induced Huntington ' s disease ( HD ) like symptoms in rats . - pubmed
Taken altogether , the results of the present study suggest a possible interplay of microglial modulation and anti - oxidant effect in neuroprotective potential of hesperidin against QA induced HD like symptoms in rats . - pubmed
Heat - processed Panax ginseng and diabetic renal damage : active components and action mechanism . - pubmed
Diabetic nephropathy is one of the serious complications in patients with either type 1 or 2 diabetes mellitus but current treatments remain unsatisfactory . - pubmed
Results of clinical research studies demonstrate that Panax ginseng can help adjust blood pressure and reduce blood sugar and may be advantageous in the treatment of tuberculosis and kidney damage in people with diabetes . - pubmed
Coinfection of WSSV and IHHNV was also detected in crabs , blue and white shrimps . - pubmed
Nonsteroidal anti - inflammatory drugs ( NSAIDs ) , including acetylsalicylic acid ( ASA ) , improve glucose metabolism in diabetic subjects , although the underlying mechanisms remain unclear . - pubmed
Pilot study of high - intensity focused ultrasound ablation as a bridging therapy for hepatocellular carcinoma patients wait - listed for liver transplantation . - pubmed
The objective of this study was to investigate the outcomes of high - intensity focused ultrasound ( HIFU ) ablation as a bridging therapy for patients with hepatocellular carcinoma ( HCC ) who had been wait - listed for deceased donor liver transplantation ( DDLT ) . - pubmed
Patients in the BMT group had a significantly higher dropout rate ( P = 0.03 ) and significantly poorer liver function as reflected by higher Model for End - Stage Liver Disease scores and higher Child - Pugh grading . - pubmed
Clinically relevant ascites was found in 5 patients in the HIFU group and 2 patients in the BMT group , but none was found in the TACE group ( P = 0.01 and P = 0.03 , respectively ) . - pubmed
In conclusion , HIFU ablation was safe even for HCC patients with Child - Pugh C disease . - pubmed
Intradural spinal malignant peripheral nerve sheath tumors ( MPNST ) are extremely rare , with only 20 adult patients reported to our knowledge , and only four primary tumors arising from the cauda equina . - pubmed
A 49 - year - old man presented with back pain , constipation , and lower extremity weakness and was found to have a large intradural lesion involving the cauda equina . - pubmed
The patient underwent laminectomy for tumor debulking and biopsy , as gross total resection was not possible due to envelopment of the cauda equina . - pubmed
However , 6 weeks later , the patient began having severe headaches , and his left temporal lobe lesion was found to have increased significantly in size , requiring craniotomy for palliative resection . - pubmed
The authors report the first adult patient with sporadic spinal MPNST with craniospinal metastasis to our knowledge . - pubmed
We would like to report an extremely rare case of simultaneous bilateral knee septic arthritis after bilateral knee intraarticular steroid injection in a rheumatoid arthritis patient . - pubmed
Electroconvulsive therapy in a patient with catatonia and an intracranial arachnoid cyst . - pubmed
METHODS : Blood samples were collected from patients with newly diagnosed asthma ( 44 , 12 males , aged 33.75?8.94 ) , newly diagnosed COPD ( 36 , 36 males , aged 68.03 + - 8.94 ) , and healthy control groups ( 23 , 9 males , aged 30.06 + - 7.50 ) . - pubmed
Its role in the mechanisms of COPD and asthma in human beings , as well as its therapeutic value in these diseases , need further investigation . - pubmed
METHODS : We retrospectively examined a cohort of 152 DM patients . - pubmed
RESULTS : Forty - three patients ( 28 % ) had cutaneous ulcers . - pubmed
We aimed to visualise non - invasively the tumour accumulation of these MoAb - targeted liposomes over time in tumour - bearing mice using multispectral optoacoustic tomography ( MSOT ) . - pubmed
MATERIALS AND METHODS : Patients sustaining a radial head fracture from 2002 - 2010 were screened for participation . - pubmed
Twenty - five patients with documented partial articular radial head fractures were identified and completed the study . - pubmed
Response to : comment on " Delayed methotrexate excretion in infants and young children with primary central nervous system tumors and postoperative fluid collections " . - pubmed
Some epidemiological and clinical studies indicate a protection of omega-3 FA against cardiovascular disease and a favourable effect on cardiovascular risk factors control in adults . - pubmed
Sulforaphane ( SFN ) is an isothiocyanate found in cruciferous vegetables with anti - inflammatory , anti - oxidant and anti - cancer activities . - pubmed
The prevalence of anemia in SCI patients with PUs was found to be approximately 35 % . - pubmed
Patients with neurologic Wilson disease ( NWD ) may worsen on treatment , but there is no study evaluating the role of oxidative stress . - pubmed
Fifty - one treatment - naive NWD patients were subjected to detailed clinical evaluation . - pubmed
The patients were considered worsened if there was one or more grade deterioration in severity scale , > 10 % deterioration in BFM score or appearance of new neurologic signs . - pubmed
MATERIAL AND METHODS : A single centre study of 106 consecutive esophagectomies performed for esophageal cancer by a minimally invasive approach in 79 patients was performed . - pubmed
Transhiatal laparoscopic esophagectomy ( THLE ) was performed in 66 patients , transthoracic esophagectomy ( TTE ) in 13 patients , with histological findings of squamous cell carcinoma in 28 and adenocarcinoma in 51 patients . - pubmed
Other serious complications included acute myocardial infarction ( 1 patient ) and necrosis of the gastroplasty ( 1 patient ) . - pubmed
Anastomotic dehiscence was observed in 8 patients , left recurrent laryngeal nerve paralysis in 8 patients , intra - abdominal abscesses in 2 patients , and pleural empyema in 1 case . - pubmed
The clinical features , imaging findings , histopatholigical examination , and management in 3 case reports of children with misdiagnosed retinoblastoma are presented . - pubmed
Mean patient age was 66.6 + - 1.1 years , 74.2 % were men , and 48.3 % had diabetes mellitus . - pubmed
Neutrophils have been shown to efficiently kill Cryptococcus neoformans , a causative agent of meningoencephalitis . - pubmed
METHODS : Fifty patients with malignant obstructive jaundice treated from September 2010 to February 2013 in Yantai Yuhuangding Hospital were included in this study . - pubmed
CONCLUSION : ( 125 ) I seeds combined with biliary stent implantation can inhibit the proliferation of vascular endothelial cells and the growth of tumor effectively , and can prolong the biliary stent patency time and the survival time obviously for patients with malignant obstructive jaundice , therefore , is a safe and effective treatment in this malignancy . - pubmed
The role of the addition of ovarian suppression to tamoxifen in young women with hormone - sensitive breast cancer who remain premenopausal or regain menstruation after chemotherapy ( ASTRRA ): study protocol for a randomized controlled trial and progress . - pubmed
BACKGROUND : Ovarian function suppression ( OFS ) has been shown to be effective as adjuvant endocrine therapy in premenopausal women with hormone receptor - positive breast cancer . - pubmed
In 2008 , the Korean Breast Cancer Society Study Group initiated the ASTRRA randomized phase III trial to evaluate the efficacy of OFS in addition to standard tamoxifen treatment in hormone receptor - positive breast cancer patients who remain or regain premenopausal status after chemotherapy . - pubmed
METHOD : Thirty patients suffering from MDD participated in the study . - pubmed
In beta - thalassemic mice transplanted with beta - thalassemic HSCs transduced with the gamma - globin / NA10HD vector , the number of fetal hemoglobin ( HbF )- expressing cells was significantly increased after 3 months , leading to resolution of the anemia . - pubmed
The combined treatment with weekly paclitaxel and PNC-27 was tested in an intraperitoneal mouse model of ovarian cancer ( ID8 ) . - pubmed
The initial neurologic signs of 212 individuals exposed to gradual ( N=114 ) and rapid ( N=98 ) onset + Gz acceleration stress , inducing the ischemic LOC phase in 83.3 + -18.6s and 8.89 + -1.52s ; p<0.001 respectively , were determined . - pubmed
Effects of the " plate model " as part of dietary intervention on modification of selected cardiometabolic risk factors in post - myocardial infarction patients : study protocol for a randomized controlled trial . - pubmed
Healthy eating as a cost - effective approach to risk reduction in post - myocardial infarction patients is proven to be beneficial , and the " plate model " is one of the practical methods to achieve this objective . - pubmed
The caustic ( NaOH ) content in bauxite residue leads to human health risks , like dermal problems and irritation to eyes . - pubmed
Here , we determine the frequency of these mutations and define the genotype - phenotype characteristics in a large cohort of patients diagnosed clinically with PAH . - pubmed
CASE PRESENTATION : We reported a 52 - year - old woman who complained of dyspnea for 2 months and dry cough for 10 days . - pubmed
Surgery remains the preferred treatment for patients with primary cardiac angiosarcoma . - pubmed
CONCLUSION : Elevated NLR predicts worse outcomes in patients with HNSCC . - pubmed
MATERIALS AND METHODS : From 2004 to 2012 , 75 patients underwent TSA for primary osteoarthritis with minimum 5 - year follow - up . - pubmed
RESULTS : Qualitative evaluation of cyst formation resulted in the following distribution : no cysts in 8 patients ( 11 % ) , small cyst formation in 27 ( 36 % ) , medium cysts in 19 ( 25 % ) , and large cysts in 21 patients ( 28 % ; kappa = 0.605 ) . - pubmed
All revised patients were in the groups with medium or large cysts . - pubmed
Treatment Based on Cinacalcet Reduces Oxidative Stress in Hemodialysis Patients with Secondary Hyperparathyroidism . - pubmed
BACKGROUND / AIMS : Oxidative stress is one of the leading factors contributing to increased mortality in patients with chronic kidney disease ( CKD ) and secondary hyperparathyroidism ( sHPT ) . - pubmed
Cinacalcet is now commonly used in the treatment of sHPT in patients with CKD . - pubmed
CONCLUSIONS : ( 1 ) Six - month treatment based on cinacalcet seems to reduce oxidative stress markers in maintenance hemodialysis patients with sHPT . - pubmed
RESULTS : Fifty - one articles met inclusion criteria , resulting in 6,227 patients who underwent mesh repair of a ventral hernia . - pubmed
Changes in cell differentiation and proliferation lead to production of abzymes in EAE mice treated with DNA - Histone complexes . - pubmed
Experimental autoimmune encephalomyelitis ( EAE)-prone C57BL/6 mice are used as a model of human multiple sclerosis . - pubmed
Adult Zebrafish Injury Models to Study the Effects of Prednisolone in Regenerating Bone Tissue . - pubmed
Furthermore , zebrafish are able to heal bone rapidly after trepanation of the skull , and repair fractures that can be easily introduced into zebrafish bony fin rays . - pubmed
We provide a workflow on how to prepare for immunosuppressive treatment in adult zebrafish , illustrate how to perform fin amputation , trepanation of calvarial bones , and fin fractures , and describe how the use of glucocorticoids affects both bone forming osteoblasts and cells of the monocyte / macrophage lineage as part of innate immunity in bone tissue . - pubmed
Renal carcinoma presents a rapid progression in patients with high metastasis with no effective therapeutic strategy . - pubmed
Processing sweet corn ( Zea mays ) growers in New York are more concerned about the cost effectiveness of fungicide use against foliar fungal diseases ( common rust and Northern corn leaf blight ) and less about whether such sprays will reduce disease intensity . - pubmed
Predicting stroke in patients without atrial fibrillation . - pubmed
BACKGROUND : Only few studies in selected cohorts have examined whether the CHA2 DS2 -VASc score can predict the risk of atrial fibrillation and thromboembolic events in patients without atrial fibrillation . - pubmed
We excluded patients with atrial fibrillation , anticoagulant therapy and follow - up & lt;30 days . - pubmed
Patients with a CHA2 DS2 -VASc score of 3 had a rate of ischaemic stroke / transient ischaemic attack / systemic embolism of 1.30 per 100 person - years . - pubmed
CONCLUSIONS : Among patients undergoing coronary angiography , the CHA2 DS2 -VASc score predicted a future diagnosis of atrial fibrillation and the composite risk of ischaemic stroke , transient ischaemic attack or systemic embolism in patients without atrial fibrillation . - pubmed
A CHA2 DS2 -VASc score of 3 was associated with a risk that would justify prophylactic oral anticoagulation treatment in a patient with atrial fibrillation . - pubmed
Rangelia vitalii is the protozoan responsible for a febrile tick - borne disease known as " Nambiuvu " or " bleeding plague . " - pubmed
Children and their parents were enrolled prior to surgery and completed baseline psychological instruments assessing parental anxiety ( STAI ) , parental coping style ( MBSS ) , child temperament ( EAS ) and parental medication administration attitude questionnaire ( MAQ ) . - pubmed
Postoperatively , parents and children completed at - home pain severity ratings ( Faces Pain Scale - Revised , children ; Numeric Rating Scale , parents ) on postoperative recovery days 1 , 2 , and 3 , reflecting an overall pain level for the past 24 h. Parents also completed a log of analgesic administration . - pubmed
CONCLUSIONS : Since parents overestimate their child 's postoperative pain and may administer more analgesics to their child , it is essential to develop a standardized method of child pain assessment and a tailored recommended postoperative analgesic regimen amongst medical providers for children undergoing T&A. - pubmed
Simple Cholecystectomy Is Adequate for Patients With T1b Gallbladder Adenocarcinoma & lt ; 1 cm in Diameter . - pubmed
This study attempts to better define the current criteria for local treatment of T1b GBA , by examining the relationship between lymph node ( LN ) metastasis and tumor size in such patients . - pubmed
Patients and methods : Clinical data from patients with T1b GBA receiving curative surgical treatment between 2004 and 2015 were collected from the Surveillance , Epidemiology , and End Results ( SEER ) database . - pubmed
Among them , 23 patients had tumors & lt;1 cm in diameter , none of which had LN metastasis ; 104 patients had tumors & gt;=1 cm , 15 of which had positive LNs . - pubmed
A clinical benefit was observed in T1b GBA patients with a tumor size & gt;=1 cm receiving EC vs. those receiving SC ( P = 0.012 ) . - pubmed
Continuous contact of air pollutants on human skin has produced early ageing and led to roughness , dryness , poor elasticity , increased wrinkling and irregular pigmentation of the skin . - pubmed
The skin melanin , erythema , moisture and elasticity values of both the right and left cheeks of the volunteers were measured at baseline visits : 15 , 30 , 45 , 60 , 75 and 90 days of time intervals . - pubmed
CONCLUSION : Treatment with crisaborole 2 % ointment was well - tolerated and led to clinical improvement in subjects with intertriginous , anogenital , or facial psoriasis . - pubmed
OBJECTIVE : The aim of this study was to delineate the kinetics of coagulation dysregulation after injury in children . - pubmed
SUMMARY BACKGROUND DATA : Trauma - induced coagulopathy is common and portends poor outcomes in severely - injured children . - pubmed
METHODS : Records of severely injured children age & lt;18 years with rapid thromboelastography ( TEG ) on arrival and documented time of injury were queried . - pubmed
RESULTS : A total of 285 patients were included : median ( interquartile range ) age = 11 ( 6 - 15 ) , injury severity score = 17 ( 10 - 25 ) , 75 % blunt mechanism , 32 % severe TBI , 11 % mortality , 28 % functional disability . - pubmed
Patients with TBI had significant increase in incidence of fibrinolysis SD beyond 1 hour after injury as compared to non - TBI patients . - pubmed
Effect of Empagliflozin on Cardiac Function , Adiposity , and Diffuse Fibrosis in Patients with Type 2 Diabetes Mellitus . - pubmed
This prospective study enrolled 35 patients ( 48.6 % men , age 63.5 + - 9.7 years ) with type 2 diabetes mellitus ( T2DM ) from June 1 , 2017 , to November 31 , 2018 . - pubmed
This study demonstrated that 6 months of empagliflozin treatment did not significantly improve the LV function , structure , adiposity , and diffuse fibrosis in patients with T2DM . - pubmed
The Proteolytic Fraction From Vasconcellea cundinamarcensis Latex Displays Anti - Inflammatory Effect in A Mouse Model of Acute TNBS - Induced Colitis . - pubmed
The proteolytic fraction ( P1G10 ) from Vasconcellea cundinamarcensis , displays gastric protective and healing activities in different skin lesions in mice and human . - pubmed
Based on these data , we assessed its anti - inflammatory activity in murine colitis model , induced by 2,4,6 - trinitrobenzenesulfonic acid ( TNBS ) adopted by its physiopathological similarity with human colitis . - pubmed
MATERIALS AND METHODS : This is a prospective interventional trial on 27 naive patients with BPH and lower urinary tract symptoms ( LUTS ) . - pubmed
PV reduction in patients without metabolic syndrome ( DeltaPVV1nMetS -4.7 mL,95%CI -7.3;-2.0 ) was greater than in affected patients ( DeltaPVV1MetS 1.7 mL,95%CI -2.69;6.1)(p=0.017,Relative RiskMetS = 6 ) . - pubmed
Patients with moderate - severe LUTS and without MetS seem to benefit more from this treatment . - pubmed
CONCLUSION : PEMF reduces PV and improves LUTS in a relative short time , in BPH patients . - pubmed
These benefits seem greater in those patients with moderate - severe LUTS but without MetS. - pubmed
Aripiprazole in youth with intellectual disabilities : A retrospective chart study . - pubmed
A retrospective chart study of patients on open - label aripiprazole treatment was conducted in the Netherlands to add to the knowledge of aripiprazole in children and young adults with mild and borderline intellectual disabilities ( IDs ) . - pubmed
For 83 % of the patients , disruptive behavior was the main target symptom . - pubmed
Mild adverse events were observed in 53 % of the patients of which fatigue and weight gain were the most common . - pubmed
In 53 children and young adults with mild and borderline IDs , aripiprazole was effective in both the short and the long term . - pubmed
On average , presentation is about 20 years after radiotherapy , and patients commonly present with headaches , complex seizures , and stroke - like symptoms . - pubmed
CASE REPORT We present one such case of a 28 - year - old man who presented to our Emergency Department with a gradually progressive severe headache and right - sided weakness developing over a few hours . - pubmed
Even in very severe cases of RSV infection treatment modalities like NO , HFOV and ECMO can be used successfully . - pubmed
Duodenal - Jejunal Exclusion Surgery Improves Type 2 Diabetes in a Rat Model Through Regulation of Early Glucose Metabolism . - pubmed
OBJECTIVES : Metabolic surgery has been proven to be widely effective for the control of glucose and weight in patients with type 2 diabetes and obesity . - pubmed
This study aimed to measure the effects of duodenal - jejunal exclusion on glycometabolism in nonobese rats with type 2 diabetes and to investigate its mechanisms . - pubmed
CONCLUSIONS : Duodenal - jejunal exclusion surgery is an effective procedure for improving glucose metabolism independent of weight loss in nonobese rats with diabetes . - pubmed
Healthcare professionals have been infected with the virulent severe acute respiratory syndrome coronavirus-2 ( SARS ) , which spreads by close contact and aerosols . - pubmed
Prenatally androgenized ( PNA ) mice mimic neuroendocrine aspects of polycystic ovary syndrome ( PCOS ) . - pubmed
Therefore , the risk of human colonization / infection with MRSA linked to the handling of raw milk or consumption of contaminated dairy products should not be ruled out . - pubmed
Children born with HHcy have musculoskeletal abnormalities / growth retardation . - pubmed
Collectively , results imply that individuals with mild / moderate HHcy seem more prone to skeletal muscle injury and its dysfunction . - pubmed
The effect of bio / organic fertilizers on the phytotoxicity of sulfadiazine to Echium amoenum in a calcareous soil . - pubmed
To tackle this question , we established an experimental platform for human diffuse gastric cancer that enables accurate modeling of histological subtypes . - pubmed
METHODS : Seven patient - derived diffuse gastric cancer organoid lines were established characterized by histopathological analysis , in situ hybridization and gene expression analysis . - pubmed
GFP - labeled gastric cancer organoids were xenotransplanted into immune - deficient mice for in vivo assessment . - pubmed
The association between Wnt target gene expression and histological subtypes was confirmed in three patient - derived gastric cancer tissues . - pubmed
Our results decoded how genetic mutations and the tumor environment shape pathohistological and biological phenotypes in human diffuse gastric cancers . - pubmed
METHODS : Retinal thickness was measured using spectral - domain optical coherence tomography in a 78 - week randomized placebo - controlled trial of verubecestat in 1,785 patients with mild - to - moderate AD . - pubmed
BACKGROUND : Personalized ENCALS survival prediction model reliably estimates the personalized prognosis of patients with amyotrophic lateral sclerosis . - pubmed
CASE REPORT : A 43 - year - old woman presented with symptoms of acute abdominal pain . - pubmed
Plant growth - promoting experiments with the use of Waito - C rice seedlings show that some of the fungal strains could encourage a more efficient growth than others . - pubmed
Impact of diabetes status in patients suffering of non - valvular atrial fibrillation requiring anticoagulation have been analysed previously and risk / benefit balance of NOACs have been confirmed in these patients . - pubmed
The usual culprits - yeasts belonging to the genera Malassezia and Candida - are commensal species in the skin that can cause opportunistic infections . - pubmed
CONCLUSIONS : Cell surface GAGs appear to play a role in the adhesion of C albicans and Malasezzia species to keratinocytes . - pubmed
Clindamycin - induced enterocolitis in hamsters as a model of pseudomembranous colitis in patients . - pubmed
Stools from a patient with antibiotic - associated colitis and cecal contents from a hamster with clindamycin - induced enterocolitis were compared in a cytotoxicity assay to determine common properties . - pubmed
These results indicate that clindamycin - induced enterocolitis in hamsters is a model of human disease and implicate toxin - producing clostridia as responsible agents . - pubmed
Report of a case of bacterial sepsis caused by a naturally occurring variant form of Staphylococcus aureus . - pubmed
In a 6 - week open study in 24 patients with rheumatoid arthritis , tolmetin was shown to have analgesic and anti - inflammatory activity at daily doses in excess of 1200 mg per day and produced statistically significant reductions in overall joint pain , walking time and articular index . - pubmed
The drug was well tolerated , but 2 patients were withdrawn because of persistent indigestion and 1 because of an urticarial type rash . - pubmed
Mothers were fed a diet containing 2 % lead acetate acording to the Pentschew - Garro model for inducing lead encephalopathy in young rats . - pubmed
Congenital malformations of the mitral valve in children . - pubmed
Associated lesions ( ventricular or atrial septal defects , coarctation , or aortic valve stenosis ) were present in 31 patients ( 65 per cent ) and were corrected during the same operation . - pubmed
Minimal or moderate regurgitation and cardiomegaly persisted in the majority of the patients . - pubmed
[ Early recognition of the child with behavior disorders ] . - pubmed
However , the magnitude of the changes in blood pressure was less in portal hypertensive rats . - pubmed
Monitoring of patients with rheumatoid arthritis in longterm administration of D - penicillamine . - pubmed
Acute infection with lymphocytic choriomeningitis virus causes a severe immune suppression in immunocompetent mice by triggering a T cell - mediated immunopathology , probably directed against infected macrophages and dendritic cells . - pubmed
Osteoporosis is a frequent complication of rheumatoid arthritis ( RA ) , especially in postmenopausal women , and may involve both juxtaarticular and generalized bone loss . - pubmed
To examine the effect of exogenous estrogens and endogenous androgens on bone loss in RA we determined rates of bone loss by serial bone density measurement for up to 4 years in 38 postmenopausal women with RA . - pubmed
To remove regionally recurrent cancer of the rectum completely , more radical extensive resections were attempted than the conventional ones in 35 patients . - pubmed
[ The therapy of the metritis , mastitis , agalactia ( MMA ) complex of swine ] . - pubmed
The severity of excitotoxic brain injury is dependent on brain temperature in immature rat . - pubmed
The effect of brain temperature on the severity of excitotoxic brain injury was evaluated in perinatal rats . - pubmed
Animals were sacrificed 5 days later and the severity of brain injury was assessed quantitatively by comparison of the weights of the injected and contralateral cerebral hemispheres . - pubmed
Injection of NMDA consistently produced extensive unilateral brain injury in rats maintained at normothermia ( 36 degrees C ambient temperature ; 29 + /- 1.8 % reduction in the weight of the injected hemisphere ) . - pubmed
Two patients , a 64 - year - old woman and a 40 - year - old man , developed a lupuslike syndrome due to lovastatin therapy , confirmed by signs , symptoms , and positive fluorescent antinuclear antibodies are herein published . - pubmed
Rotavirus - specific cytotoxic T lymphocytes passively protect against gastroenteritis in suckling mice . - pubmed
Rotavirus - specific cytotoxic T lymphocytes may be important in either amelioration of acute infection or protection against reinfection . - pubmed
Strain gauge plethysmography in the assessment of venous reflux after subfascial closure of perforating veins : a prospective study of twenty patients . - pubmed
In 10 patients ( 50 % ) the valves of the deep veins were incompetent as verified by Doppler ultrasonography , and deep vein thrombosis had previously been diagnosed in seven patients . - pubmed
In two of four patients with fair subjective results the arterial flow was pathologically high , which probably implies the presence of microscopic arteriovenous fistulas . - pubmed
Although the question of booster dose for residual primary lesion arises in only 5 % of nasopharyngeal carcinoma patients receiving radiotherapy , it poses a difficult problem for clinicians and should be followed . - pubmed
Three out of six men infected with HIV had had previously syphilis . - pubmed
The application of these techniques in two murine tumour systems provides evidence that such hypoxia exists and reduces the effectiveness of single doses of radiation . - pubmed
Classical endoscopic vesical neck suspension was performed in 93 patients with cure of incontinence in 89 ( 95.7 % ) . - pubmed
The following topics are covered in this brief review on the environmental and occupational toxicology of chromium : occurrence , production and uses of chromium and chromium compounds ; experimental toxicology ; chromium toxicity for man ; hygienic and ecologic aspects of chromium contamination of the environment . - pubmed
Esotropic children with amblyopia : effects of patching on acuity . - pubmed
The rates of improvement of acuity in response to full - time occlusion therapy of 30 esotropic patients with amblyopia were determined . - pubmed
The age - related changes in responsiveness to patching were modeled nonlinearly to provide quantitative guidelines for management of occlusion therapy of esotropic children with amblyopia . - pubmed
Suppression of exercise - induced angina by magnesium sulfate in patients with variant angina . - pubmed
The effects of intravenous magnesium on exercise - induced angina were examined in 15 patients with variant angina and in 13 patients with stable effort angina and were compared with those of placebo . - pubmed
Exercise - induced angina associated with transient ST segment elevation occurred in 11 patients with variant angina receiving placebo and in only 2 of these patients receiving magnesium ( p less than 0.005 ) . - pubmed
On the other hand , exercise - induced angina was not suppressed by magnesium in any patient with stable effort angina . - pubmed
The size of the perfusion defect as measured by thallium-201 scintigraphy was significantly less in patients with variant angina receiving magnesium than that in those receiving placebo ( p less than 0.001 ) , whereas it was not significantly different in patients with stable effort angina receiving placebo versus magnesium . - pubmed
In conclusion , exercise - induced angina is suppressed by intravenous magnesium in patients with variant angina but not in patients with stable effort angina . - pubmed
This beneficial effect of magnesium in patients with variant angina is most likely due to improvement of regional myocardial blood flow by suppression of coronary artery spasm . - pubmed
Mice were treated at the non - lethal dose of 100 mg kg-1 which inhibited tumour growth almost completely . - pubmed
In non - tumour bearing mice we studied the time course of the reversal of the haematological toxicity of 5FU . - pubmed
[ Metastatic calcinosis in patients on long - term dialysis ] . - pubmed
A 14 year - old boy with coeliac disease and poorly treated diabetes mellitus and pulmonary tuberculosis due to INH resistant BK presented with a permanent malabsorption of rifampicin . - pubmed
The size of the foramen magnum in patients with achondroplasia was small at all ages , particularly in those with serious neurologic problems . - pubmed
The data suggest that measurement of the foramen magnum may identify achondroplastic individuals at high risk of developing neurologic complications . - pubmed
Onset and development of anaemia in sheep experimentally infected with Schistosoma mattheei -- ferrokinetic studies . - pubmed
[ Evolution of the ultrastructure of the ovoendometrial connections under the influence of estrogen in the rat during experimental retardation of nidation ] . - pubmed
Acetylsalicylic acid or indomethacin were found to suppress the aggregation activity of thyrotoxicosis patients ' platelets . - pubmed
Pasteurella multocida septic arthritis . - pubmed
" Non - accidental injury " and wild parsnips . - pubmed
Facultative Pasteurella ophthalmitis in Hooded Lister rats . - pubmed
Hooded Lister rats were found to exhibit symptoms of Mycoplasma pulmonis infection . - pubmed
During the course of this chronic respiratory disease they developed ophthalmia and conjunctivitis which proved to be an opportunist infection with Pasteurella multocida . - pubmed
The severity of disease varied in individual rats , newborn rats entirely escaping infection . - pubmed
The altered apoprotein composition suggested that the hyperlipoproteinemia associated with cholesterol feeding in the rat is due to an inadequate rate of removal of lipoproteins of intestinal origin , and that this is greatly exacerbated by diabetes . - pubmed
This should improve the safety of the use of controlled hypotension and may well identify those patients requiring more aggressive postoperative treatment . - pubmed
In the past eight years we have treated 22 patients suffering from acute infection of the knee joint and the talo - crural joint . - pubmed
A hypertensive episode precipitated by avocados in a patient on tranylcypromine is described . - pubmed
This is the first documented case of avocado induced hypertensive crisis . - pubmed
Extraocular application of mitomycin C in a rabbit model : cytotoxic effects on the ciliary body and epithelium . - pubmed
Thirteen patients with severe aortic stenosis and left ventricular dysfunction ( ejection fraction & lt ; 0.50 , Group A ) received echocardiographic evaluation before , and early and late after isolated aortic valve replacement . - pubmed
The results were compared with those of 11 aortic stenosis patients without left ventricular dysfunction ( Group B ) . - pubmed
It is concluded from the above results , that LV contraction in aortic stenosis patients with preoperative left ventricular dysfunction improved during the late postoperative period . - pubmed
Alterations in colonic smooth muscle function in cats with idiopathic megacolon . - pubmed
OBJECTIVE : To determine whether colonic smooth muscle dysfunction is involved in the pathogenesis of idiopathic megacolon in cats . - pubmed
ANIMALS : Colon from healthy cats and cats with idiopathic megacolon . - pubmed
CONCLUSIONS : Idiopathic megacolon is a generalized dysfunction of colonic smooth muscle in cats . - pubmed
The patient is currently well with a stable engraftment 6 months following allogeneic PBSC transfusion , with no signs of acute of chronic GVHD . - pubmed
Most human organ - specific autoimmune diseases such as Hashimoto ' s thyroiditis ( HT ) are considered to be Th1 mediated , and a quantitative dominance of Th1 cells in thyroid infiltrates from both Graves ' disease ( GD ) and HT affected glands has been reported . - pubmed
Results showed a reduction of self - reported tobacco withdrawal symptoms using the nicotine patch alone . - pubmed
BACKGROUND : As many as 20 % of individuals with the clinical diagnosis of Parkinson ' s disease ( PD ) do not have the characteristic neuropathologic features of PD at post mortem . - pubmed
METHODS : We have estimated regional brain iron content in a patient with probable SND , using a novel imaging method developed in our laboratory , and have compared the results in this patient to those which we have previously reported in patients with PD and in age - matched controls . - pubmed
RESULTS : We observed that putamenal iron content was increased in our SND patient , beyond the 95 % confidence limit for inclusion in the PD group , even when considering clinical severity . - pubmed
CONCLUSIONS : The demonstration of increased putamenal iron content may be a useful adjunctive investigative procedure in patients with suspected SND . - pubmed
None of the patients undergoing partial middle turbinectomy for nasal obstruction developed frontal sinusitis postoperatively . - pubmed
Maedi - visna virus and caprine arthritis - encephalitis virus : distinct species or quasispecies and its implications for laboratory diagnosis . - pubmed
The lentiviruses responsible for causing maedi - visna or ovine progressive pneumonia in sheep and caprine arthritis - encephalitis in goats have long been considered distinct , albeit related , viral species . - pubmed
METHODS : The present longitudinal study investigated a population based group of borderline hypertensive men ( BHT , n = 66 , diastolic blood pressure ( BP ) 85 - 94 mm Hg ) . - pubmed
Characterization of mouse parvovirus infection among BALB / c mice from an enzootically infected colony . - pubmed
A correlation ( r = 0.250 , P = 0.0089 ) was evident between the presence of HPV 16 and occurrence of invasive cancer . - pubmed
Linomide is a synthetic immunomodulator that has been shown to protect animals against a wide range of spontaneously developing or induced autoimmune diseases . - pubmed
We have previously reported that Linomide blocks both the clinical and the histopathological manifestations of experimental autoimmune encephalomyelitis ( EAE ) in various animal models . - pubmed
It had a marked therapeutic effect in the treatment of staphylococcal sepsis in albino mice and was low toxic . - pubmed
HMA was also used to simplify the identification of mixed infection with two HCV genotypes . - pubmed
Septic complications were responsible for early death and disease recurrence for late patient loss . - pubmed
Radiofrequency catheter ablation has established itself as a first line therapy for the curative treatment of many patients with supraventricular or atrioventricular tachycardias and also for selected types of ventricular tachycardia . - pubmed
In patients undergoing radiofrequency ablation procedures , radiation exposure carries a small but measurable risk of malignancy and hereditary disorders . - pubmed
In patients undergoing ablation of ventricular tachycardia , a higher incidence of total procedure related complications between 5 - 7 % and severe complications ( 3 - 4 % ) may be expected . - pubmed
Follow - up information on 10 patients ( range : 6 to 77 months ; median : 18 months ) showed no recurrence . - pubmed
A 26 - year - old man who underwent aortic valve replacement for aortic regurgitation due to Takayasu ' s arteritis 2 years earlier experienced left amaurosis persisting for some minutes . - pubmed
Following administration of a calcium antagonist , the patient 's amaurosis subsided and brain bloodstream scintigraphy showed no abnormalities . - pubmed
PURPOSE : To evaluate the diagnostic accuracy of contrast - enhanced magnetic resonance angiography ( CE - MRA ) MoBI - trak of peripheral vessels in patients with peripheral vascular disease who were candidates for digital subtraction angiography ( DSA ) . - pubmed
RESULTS : The presence of both galactitol and galactonate was identified in RBC of 15 galactosemic and 13 normal subjects by their mass spectra and chromatographic comparisons with both unlabeled and 13C labeled standards . - pubmed
CONCLUSION : The determination of these compounds in RBC along with galactose-1 - phosphate ( gal-1 - P ) in the same procedure provides the potential for their use in better monitoring of diet therapy in galactosemic patients . - pubmed
CONCLUSION : Tuberculosis should be entertained as a possible diagnosis in patients with nonspecific laryngeal disease . - pubmed
Nonetheless , by the description of aberrant induction and/or maintenance of the mammary rudiments in a variety of inbred mouse strains and mutants , we have accumulated data demonstrating that the mammary rudiments develop independently of each other at these positions . - pubmed
Plasticity in the tonotopic organization of the medial geniculate body in adult cats following restricted unilateral cochlear lesions . - pubmed
To investigate subcortical contributions to cortical reorganization , the frequency organization of the ventral nucleus of the medial geniculate body ( MGv ) in six normal adult cats and in eight cats with restricted unilateral cochlear lesions was investigated using multiunit electrophysiological recording techniques . - pubmed
The tonotopic organization of MGv in the lesioned animals , with severe mid - to - high frequency hearing losses , was investigated 40 - 186 days following the lesioning procedure . - pubmed
Intensification of therapy for children with lower - risk acute lymphoblastic leukemia : long - term follow - up of patients treated on Children 's Cancer Group Trial 1881 . - pubmed
PURPOSE : From December 1988 through December 1992 , the Children 's Cancer Group ( CCG ) conducted a randomized trial ( CCG-1881 ) designed to evaluate the impact of adding a single delayed intensification phase of therapy to standard therapy for patients with newly diagnosed low - risk acute lymphoblastic leukemia ( ALL ) . - pubmed
PATIENTS AND METHODS : Patients ( n = 778 ) with newly diagnosed ALL , 2 to 9 years of age at diagnosis with an initial WBC count less than 10,000 / microL , were eligible for this protocol . - pubmed
RESULTS : Patients randomized to receive DI experienced fewer relapse events in all categories . - pubmed
Restorations were examined for retention , marginal caries , marginal microleakage , sensitivity , discoloration , restorative fracture , and patient satisfaction . - pubmed
Translocation ( 11;15;19 ): a highly specific chromosome rearrangement associated with poorly differentiated thymic carcinoma in young patients . - pubmed
We report a 15 - year - old boy diagnosed with thymic carcinoma who presented with a large anterior mediastinal mass , pleural effusion , and bone metastasis . - pubmed
Several case reports of a similar chromosomal abnormality have been reported for thymic carcinoma in young patients with poor outcome . - pubmed
This karyotypic abnormality appears to mark a cohort of patients with thymic carcinoma who have a poor prognosis despite aggressive chemotherapy . - pubmed
Treatment of human brucellosis with rifampin plus minocycline . - pubmed
In order to evaluate the efficacy and tolerability of a high intravenous dose of rifampin plus oral minocycline ( administered daily for 3 weeks ) for the treatment of acute brucellosis , we retrospectively reviewed the outcome of 239 consecutive patients ( 135 adults and 104 children ) diagnosed and treated over a 17 - year period in Italy . - pubmed
[ Investigations and public health aspects on human toxoplasmosis ] . - pubmed
[ Histochemical studies on cure process of ascitic tumors of rats ] . - pubmed
[ PREVENTIVE ACTION OF CYSTAMINE AND SOME OF ITS DERIVATIVES IN EXPERIMENTAL TOXIC PULMONARY EDEMA IN LABORATORY ANIMALS ] . - pubmed
METHODS : The clinical presentation of pertussis was studied in children who participated in a randomized , controlled clinical trial of efficacy of acellular pertussis vaccine . - pubmed
Children who received an antibiotic had a duration of cough 6 to 11 days longer and spasmodic cough 4 to 13 days longer than untreated patients . - pubmed
Girls had a duration of spasmodic cough 7 days longer than boys only after 3 years of age . - pubmed
Streptococcus pneumoniae remains the most important pathogen ; however , emerging resistance of this organism to antimicrobial agents has affected empirical treatment of CAP . - pubmed
Is the abuse of cannabis related to psychopathology , HIV / HCV risk - taking and infectious diseases ? - pubmed
METHOD : Overlapping samples of either the entire clinic population ( n = 283 ) or all the patients who had completed 1 year of MMT treatment ( n = 196 of which 20 were re - entering ) underwent random and twice - weekly observed urine analysis for various drugs of abuse , responded to self - report questionnaires ( SCL-90 - R ; HIV / HCV risk - taking behaviours ; n = 164 ) , interviews ( ASI , n = 176 ; SCID , n = 151 ) and hepatitis C and HIV testing ( n = 149 ) . - pubmed
Cannabis abusers did not suffer from more psychological distress , infectious diseases , and did not engage in more HCV / HIV risk - taking behaviour , nor did they leave treatment earlier than NCAs . - pubmed
Patients referred for surgical lung biopsy as part of a diagnostic evaluation of interstitial lung disease ( ILD ) were evaluated . - pubmed
MATERIAL AND METHODS : A total of 167 people with myopia ( 117 women and 50 men ) of the age between 12 and 51 were examined . - pubmed
Shortly after CVVH , the patient was diagnosed with HIT and placed on an Argatroban infusion . - pubmed
This case report summarizes the use of Argatroban during VAD and ECMO support for a patient diagnosed with HIT . - pubmed
The value of thalidomide - dexamethasone was assessed in 26 consecutive , previously untreated patients with multiple myeloma of high tumor mass . - pubmed
There were no occurrences of grade 3 or 4 neutropenia or thrombocytopenia , so that serious infection occurred in only 12 % of patients . - pubmed
Vagus nerve stimulation suppresses pain but has limited effects on neurogenic inflammation in humans . - pubmed
Left vagus nerve stimulation reduces pain perception in humans . - pubmed
To test whether VNS also affects activation of primary nociceptive afferents in humans , we investigated 11 patients before and after implantation of a vagus nerve stimulator by using tonic pressure as pain stimulus . - pubmed
OBJECTIVE : The purpose of this study was to test the hypothesis that no significant difference exists in the speech outcomes between patients with severe velopharyngeal incompetence ( VPI ) who receive a pharyngeal flap and patients with less severe VPI who receive a Z - plasty for management of VPI . - pubmed
Modified technique of hepatic vascular exclusion : effect on blood loss during complex mesohepatectomy in hepatocellular carcinoma patients with cirrhosis . - pubmed
This study was designed to compare the overall outcomes after application of CIO with or without occlusion of the ICV below the liver in complex mesohepatectomy for hepatocellular carcinoma ( HCC ) patients with cirrhosis . - pubmed
CONCLUSIONS : CIO with occlusion of the ICV below the liver is a safe , effective , and feasible technique during mesohepatectomy in HCC patients with cirrhosis . - pubmed
BACKGROUND : The majority of patients with hepatitis C virus ( HCV ) infection suffer from disabling fatigue , cognitive dysfunction , and quality of life reduction . - pubmed
Recent studies have shown that fatigue and psychomotor slowing may resolve in patients with hepatitis C after treatment with ondansetron . - pubmed
This observation indicates alteration of serotonergic neurotransmission in HCV infected patients with chronic fatigue . - pubmed
METHODS : Data from 20 HCV infected patients who were referred to our clinic because of disabling fatigue and cognitive decline of unknown cause were analysed retrospectively . - pubmed
RESULTS : All patients had pathological results on the fatigue impact scale . - pubmed
Comorbidity that could have impaired cerebral function was excluded in all patients . - pubmed
CONCLUSION : Our findings indicate alteration of serotonergic and dopaminergic neurotransmission in HCV infected patients with chronic fatigue and cognitive impairment . - pubmed
alpha - TEA inhibits survival and enhances death pathways in cisplatin sensitive and resistant human ovarian cancer cells . - pubmed
Pro - death and pro - life signaling pathways were studied to understand the anti - cancer actions of alpha - TEA on cisplatin - sensitive ( A2780S ) and -resistant ( A2780 / cp70R ) human ovarian cancer cells . - pubmed
In this experimental study , the functional changes of the endothelial cells were investigated in the aortic rings of rats subjected to 50 mg Si / kg body weight in their drinking water for 8 days . - pubmed
The case describes a 38 - year - old woman presenting a multilocular radiolucency affecting the entire right half of the lower jaw , with an unerupted third molar displaced to the region of the coronoid process . - pubmed
It has been proven that HAART is effective in suppressing human immunodeficiency virus ( HIV ) replication , decreasing morbidity and mortality associated with HIV and improving quality of life in adults as well as children infected with HIV . - pubmed
Probiotic treatment of rat pups normalises corticosterone release and ameliorates colonic dysfunction induced by maternal separation . - pubmed
This paper describes the application of proteomics to incised wounds of the rat to determine if this technology could be applied to the important forensic issue of determining the age of wounds . - pubmed
Experimental incised skin wounds were inflicted on rats 5 , 15 , 30 and 60 minutes , 3 , 6 , 12 and 24 hours and 2 , 5 , 7 and 12 days before euthanasia . - pubmed
BACKGROUND : Uterine artery embolization ( UAE ) is promising , minimally invasive therapy being offered to women for treatment of fibroids . - pubmed
CASE : A patient treated with UAE for a huge cervical fibroid presented with an infected , necrotic cervical mass lesion 4 weeks after the procedure . - pubmed
Spontaneous vaginal expulsion of the infected cervical fibroid from the left lateral cervical fistula tract occurred 3 weeks later while the patient was receiving antibiotic therapy . - pubmed
METHODS : We studied retrospectively the medical records of 42 eyes of 42 patients with persistent cystoid macular edema secondary to BRVO , eyes in which the foveal thickness was greater than 250 microm at final examination . - pubmed
CONCLUSIONS : Oral mucositis in patients who have undergone bone marrow transplantation can be quantified reliably with the easily administered PROMS scale . - pubmed
The PROMSscale provides a valid measure of the impact of oral mucositis on the oral - health - related quality of life of patients affected by this malady . - pubmed
OBJECTIVES : The aim of this study was to investigate the evolution of lung function during the first 6 years of life after a clinical diagnosis of cystic fibrosis ( CF ) in infancy in children with CF and in healthy control subjects . - pubmed
MEASUREMENTS AND MAIN RESULTS : Forty - eight children with CF and 33 healthy control subjects had up to seven ( median , 3 ) measurements . - pubmed
Wheeze on auscultation , recent cough , and Pseudomonas aeruginosa ( PsA ) infection ( even if apparently effectively treated ) were all independently associated with further reductions in lung function . - pubmed
PURPOSE : To investigate the effect of multislice computed tomography ( CT ) protocols on the visualization of target vessel stents in patients with abdominal aortic aneurysm ( AAA ) treated with fenestrated endovascular grafts . - pubmed
METHODS : Twenty - one patients ( 19 men ; mean age 75 years , range 63 - 86 ) undergoing fenestrated endovascular repair of AAA were retrospectively studied . - pubmed
Burkholderia cepacia complex ( BCC ) is an opportunistic pathogen that occasionally causes hospital outbreaks . - pubmed
Human genetic factors and respiratory syncytial virus disease severity . - pubmed
SUMMARY : To explain the wide spectrum of disease severity caused by respiratory syncytial virus ( RSV ) and because of the limitations of animal models to fully parallel human RSV disease , study of genetic influences on human RSV disease severity has begun . - pubmed
They are valuable since an understanding of the direction of a polymorphism 's effect can help construct a meaningful human RSV disease pathogenesis model . - pubmed
Chronic prosthetic joint infection caused by Listeria monocytogenes . - pubmed
We report what is to the best of our knowledge the first case of persistent human listeriosis . - pubmed
Infection of the device with Listeria monocytogenes occurred and persisted for 2 years . - pubmed
METHOD : The right musculocutaneous nerve in 16 adult male Sprague - Dawley rats was transected to induce biceps muscle paralysis . - pubmed
Effects of sphingosylphosphorylcholine against cholestatic oxidative stress and liver damage in the common bile duct ligated rats . - pubmed
The goal of this study was to evaluate the possible protective effects of sphingosylphosphorylcholine ( SPC ) against cholestatic oxidative stress and liver damage in the common bile duct ligated rats . - pubmed
Electrocardiographic change after recanalization in a patient with recent extensive anterior wall myocardial infarction . - pubmed
In parallel , patients in end - stage renal failure show an increase in arterial stiffness . - pubmed
Curiously , the PWV value observed in arms with an AVF was significantly lower in diabetic than in non - diabetic hemodialyzed patients ( NDHP ) ( 8.00 + /- ; 2.86 m / s and 10.38 + /- ; 2.33 m / s ; respectively ) . - pubmed
This diagnosis in a pregnant patient with neurofibromatosis type 1 poses additional treatment dilemmas . - pubmed
Management of pregnant patients with rare , rapidly growing tumors may require early delivery in cases where maternal health is in jeopardy . - pubmed
Outcome of experimental rat vaginitis by Candida albicans isolates with different karyotypes . - pubmed
albicans isolates with b and c karyotypes was analyzed in vivo using a model of experimental rat vaginitis . - pubmed
Three patients developed hernias following laparotomy from severe injuries sustained during combat . - pubmed
Canine heartworm is endemic in many parts of the world , and veterinarians rely on rapid in - clinic antigen tests to screen for this infection . - pubmed
Because of the widespread use of heartworm prevention and possible false negative test results in dogs with low heartworm burdens , the performance of the VetScan VS2 ( ) HW test and a commercially available in - clinic , membrane - based ELISA test ( SNAP ( ) Heartworm RT Test ; IDEXX Laboratories ) was compared using samples from dogs with low heartworm burdens and/or low levels of circulating antigen . - pubmed
The purpose of this study was to investigate the mechanisms of aspiration with respect to the viscosity of ingested material in patients with dysphagia . - pubmed
Seventy patients with dysphagia underwent videofluoroscopic swallow studies ( VFSS ) between May 1 , 2009 and September 30 , 2009 . - pubmed
Pleomorphic xanthoastrocytoma : MR imaging findings in 19 patients . - pubmed
RESULTS : The clinical presentation in 18 patients included : dizziness ( 8) ; headache ( 9 ) ; and epilepsy ( 8) . - pubmed
Natural killer ( NK ) cell cytotoxicity was assessed using peripheral blood mononuclear cells from 103 healthy volunteers and 51 cancer patients . - pubmed
CASE PRESENTATION : Here we present a 56 - year - old man with advanced lung adenocarcinoma who developed a remittent fever together with pharyngodynia and joint pain after first cycle of chemotherapy with paclitaxel plus carboplatin . - pubmed
The patient was finally diagnosed as AOSD - like PNS considering the good and prompt response to a short - term administration of non - steroidal anti - inflammatory drug and subsequent cycles of effective chemotherapy with pemetrexed plus cisplatin . - pubmed
DISCUSSION AND CONCLUSIONS : Though rare , AOSD - like PNS can be one of the potential diagnoses in lung cancer patients with fever of undetermined origin , especially those having no response to antibiotic treatment . - pubmed
OBJECTIVE : To provide a practical review of the spectrum of possible imaging findings in patients with progressive multifocal leukoencephalopathy ( PML ) and to address differentials . - pubmed
We describe the clinical features and serial NCS findings of a patient with PCB / FS . - pubmed
Insulin resistance in patients with chronic kidney disease . - pubmed
Insulin resistance ( IR ) plays a central role in the metabolic syndrome and is associated with increased risk for CKD in nondiabetic patients . - pubmed
IR is common in patients with mild - to - moderate stage CKD , even when the glomerular filtration rate is within the normal range . - pubmed
In patients with end stage renal disease , IR is an independent predictor of cardiovascular disease and is linked to protein energy wasting and malnutrition . - pubmed
The authors review relevant clinical trials looking at the efficiency and safety of ticagrelor focusing predominantly on the management of patients with ACS . - pubmed
The challenge for prescribers is to identify those most likely to benefit from ticagrelor treatment while minimizing unnecessary bleeding events for ' real - world ' ACS patients . - pubmed
Longitudinal liver stiffness assessment in patients with chronic hepatitis C undergoing antiviral therapy . - pubmed
The effect of antiviral treatment and virologic response on LS was assessed and compared with untreated patients with chronic hepatitis C ( CHC ) . - pubmed
METHODS : TE was performed at baseline , and at weeks 24 , 48 , and 72 in 515 patients with CHC . - pubmed
CONCLUSIONS : LS decreases during and after antiviral treatment in patients with CHC . - pubmed
Brief report : CANTAB performance and brain structure in pediatric patients with Asperger syndrome . - pubmed
Patients were classified as mild [ no necrosis or organ failure ( OF ) ] , moderate ( sterile necrosis or transient OF ) , severe [ infected necrosis ( IN ) or persistent OF ] , or critical ( IN and persistent OF ) AP . - pubmed
Three female patients had a & gt ; 2.5 microg / l increase of Co ions , associated with head sizes & lt;= 50 mm , clinical symptoms and osteolysis . - pubmed
5 - Nitrofuran derivatives were synthesized and their antibacterial activity was investigated using standard bacterial strains and clinical isolates . - pubmed
Change in inferior sclera exposure following Le Fort I osteotomy in patients with midfacial retrognathia . - pubmed
This study evaluated the decrease in sclera exposure after maxillary advancement or impaction in patients with midfacial hypoplasia . - pubmed
CONCLUSION : Inferior sclera exposure in patients with midfacial hypoplasia and retrognathia decreases significantly in accordance with the change in the lower eyelid position after maxillary advancement or impaction surgeries . - pubmed
Over the last 90 years it has become established that some patients will develop severe arterial disease of the intracranial brain arteries and suffer brain infarction . - pubmed
Smaller infarctions and brain atrophy may also be seen and over time there appear to be negative cognitive effects in some patients , with or without abnormal brain imaging . - pubmed
Focal mononeuropathies and pneumococcal meningitis are also more common in these patients . - pubmed
Brain infarction in children can largely be prevented screening children beginning at age 2 years and instituting regular blood transfusion when the Doppler indicates high stroke risk ( & gt;200cm / sec ) . - pubmed
Magnetic resonance imaging and positron emission tomography give evidence of subtle and sometimes overt brain injury due to stroke in many adults , but a preventive strategy for adults with SCD has not been developed . - pubmed
CONCLUSION : Patients with CA - AKI sustain more severe AKI than patients with HA - AKI . - pubmed
Tobacco and alcohol : the relation to pulmonary tuberculosis in household contacts . - pubmed
This study aims to detect the hidden household contacts ( HC ) cases early and to examine the relative contribution of tobacco and alcohol use to the risk of TB . - pubmed
The association between habits ( alcohol user and smoking ) and TB was found except with chewing tobacco user ( P & gt ; 0.05 ) . - pubmed
Effective campaign to discourage use of alcohol and tobacco , and awareness programme about the mode of transmission of TB are needed in community . - pubmed
However , even if most animal tumors might be a reliable model to study human carcinomas , many open questions , related to the opportunities to select and recruit new models in oncology , along with their legal and ethical implications , remain unanswered . - pubmed
Object retrieval by Norway rats consists of locomotion to an object , object seizure , carriage to a refuge and release . - pubmed
MATERIALS AND METHODS : Twelve patients with chronic pancreatitis ( CP ) underwent laparoscopic longitudinal pancreaticojejunostomy ( LPJ ) in our unit . - pubmed
All 12 patients who underwent laparoscopic LPJ had anteroposterior dimension of the pancreatic head of not more than 3 cm without any pancreatic head parenchymal calcification and with minimal stone load in the head , hence head coring was not contemplated . - pubmed
Our first eight patients who were having more than 12 months ' follow - up had pain relief and significant weight gain . - pubmed
Patients treated with teriflunomide 14 mg spent significantly fewer nights in hospital for relapse ( p = 0.009 ) and had lower annualized rates of all hospitalizations ( p = 0.030 ) . - pubmed
Psoriatic arthritis not only causes functional impairment , but also increases mortality risk of patients . - pubmed
Nevertheless , the examination of the role of human microbiota in illnesses using animal models of human diseases reared in defined ( gnotobiotic ) conditions could allow insight into the unusual complexity of the mechanisms involved in the initiation and maintenance of chronic diseases , including cancer . - pubmed
INTRODUCTION : IGF-1 deficiency in TM patients in children and adolescents has been attributed to chronic anemia and hypoxia , chronic liver disease , iron overload and other associated endocrinopathies , e.g. - pubmed
Few data are available in the literature regarding adult TM patients and growth disorders . - pubmed
The mean age of patients with GHD was 39.3 years ( range : 25 - 49 years , median : 39 years ) versus 35.8 years ( range : 27 - 45 years , median : 37.5 years ) in non - GHD patients . - pubmed
The efficacy of atomoxetine for the treatment of children and adolescents with attention - deficit / hyperactivity disorder : a comprehensive review of over a decade of clinical research . - pubmed
Atomoxetine was first licensed to treat attention - deficit / hyperactivity disorder ( ADHD ) in children and adolescents in the US in 2002 . - pubmed
, males / females , patients with co - morbidities , children / adolescents , and with / without prior exposure to other ADHD medications ) . - pubmed
Fibromyxomas are rare in children under 10 years of age . - pubmed
Although this tumor is reported most frequently in the mandible for the general population , it has rarely been reported in the mandible in children & lt;10 years of age . - pubmed
METHODS : We reviewed the 39 reported cases of odontogenic fibromyxoma in children under the age of 10 . - pubmed
RESULTS : This case represents the seventh case of odontogenic fibromyxoma of the mandible in a child under the age of 10 years reported in the English literature . - pubmed
Left atrial appendage ligation in patients with atrial fibrillation leads to a decrease in atrial dispersion . - pubmed
BACKGROUND : Left atrial appendage ( LAA ) exclusion has been performed in patients with atrial fibrillation ( AF ) to prevent thrombus formation and subsequent cardioembolic events . - pubmed
The purpose of this study was to evaluate the effect of LAA ligation on P - wave morphology in patients with AF . - pubmed
Eleven patients had paroxysmal AF and 4 patients had persistent AF ( 12 male patients and 3 female patients ) . - pubmed
This is a potential mechanism to explain the role of LAA ligation in maintaining sinus rhythm in patients with AF . - pubmed
Angelica Sinensis attenuates inflammatory reaction in experimental rat models having spinal cord injury . - pubmed
This study was aimed to evaluate the effect of Angelica Sinensis on experimental rat models in which spinal cord injury was induced by studying different factors . - pubmed
These included a sham control group where only laminectomy was performed , SCI group where SCI was induced and AS / SCI group where although SCI was induced but Angelica Sinensis was also administered to study its effect and draw a comparison with control . - pubmed
On the basis of this study we concluded that the use of 20 mg / kg Angelica Sinensis in rat models can attenuate the secondary damage caused by SCI and thus help in controlling the pathology of SCI in rats . - pubmed
Of 104 patients , 68 % exhibited one EV , 30 % two EVs , and 2 % three EVs . - pubmed
UNLABELLED : Epstein - Barr Virus ( EBV ) persists for the lifetime of the infected host despite eliciting strong immune responses . - pubmed
NK cells can kill EBV - infected cells undergoing lytic replication in vitro , and studies in both humans and mice with reconstituted human immune systems have shown that NK cells can limit EBV replication and prevent infectious mononucleosis . - pubmed
Genetically determined differences in noradrenergic function : The spontaneously hypertensive rat model . - pubmed
The spontaneously hypertensive rat ( SHR ) displays the behavioral characteristics of ADHD ( poorly sustained attention , impulsivity , hyperactivity ) and is the most widely studied genetic model of ADHD . - pubmed
The results of the present study show that noradrenergic function is similarly altered by the early life stress of maternal separation in male and female SHR , while GABA- and glutamate - regulation of norepinephrine release remained unaffected by maternal separation in the control , WKY , rat strain . - pubmed
PATIENTS AND METHODS : Immunohistochemical staining was performed in samples from 288 patients with clear cell renal cell carcinoma . - pubmed
Longitudinal analysis of hemostasis biomarkers in cancer patients during antitumor treatment . - pubmed
UNLABELLED : ESSENTIALS : Hemostasis biomarkers impact thrombosis occurrence and survival in cancer patients . - pubmed
We performed a longitudinal analysis of hemostatic parameters in 112 cancer patients . - pubmed
Hemostatic parameters are associated with disease state , patients ' prognosis , and the risk of VTE . - pubmed
BACKGROUND : Hemostasis biomarkers are known to have an impact on venous thromboembolism ( VTE ) occurrence and survival in cancer patients . - pubmed
PATIENTS / METHODS : Patients with cancer of the brain ( n = 39 ) , lung ( n = 41 ) , colon ( n = 15 ) or pancreas ( n = 17 ) were included before initiation of antitumor therapy . - pubmed
At the last blood sampling time - point before VTE occurrence , in 13 patients the D - dimer level was above the median , and in seven of these patients it was even above the 75th percentile ; however , the individual course was highly variable . - pubmed
BACKGROUND : Borrelia miyamotoi , the agent of relapsing fever , is a tick - borne spirochete first isolated in Japan in 1994 . - pubmed
In addition , two cases of meningoencephalitis caused by B. - pubmed
RESULTS : In vivo , all the SCID mice challenged with the components before storage and the RBCs stored for up to 42 days developed the infection . - pubmed
Wild - type mice also developed the infection when injected with prestorage samples from all components , while a lower number of mice were infected by RBCs stored for 42 days . - pubmed
RESULTS : Among 712 patients , 16.8 % experienced MM , of whom 53.3 % received RBCT . - pubmed
Patients who received RBCT experienced MM more commonly ( 30.8 % vs 11.1 % ; P & lt ; .001 ) . - pubmed
Of the 237 proteins detected , 13 were dysregulated in & gt;=3 of the 6 VS patients versus controls , and 13 were dysregulated ( 12 up , 1 down ) in samples from patients with class D versus class B hearing . - pubmed
Virtual human technology researches decisions about care for patients with dementia . - pubmed
CONCLUSIONS : Clozapine - induced hypersalivation is the most prevalent adverse effect experienced by patients treated with clozapine and negatively impacts on quality of life , particularly if daytime drooling is present . - pubmed
Successful treatment of postoperative multidrug - resistant Acinetobacter baumannii meningitis by tigecycline . - pubmed
Here we report a case of postoperative MDR Acinetobacter baumannii meningitis treated by tigecycline combined with colimycin for 21 days . - pubmed
BACKGROUND : The benefits of combination therapy with infliximab and azathioprine have been demonstrated in clinical trials of patients with ulcerative colitis ( UC ) and Crohn ' s disease ( CD ) . - pubmed
AIMS : We aim to compare long - term outcomes among patients with inflammatory bowel disease ( IBD ) treated with sequentially added combination therapy or monotherapy strategies . - pubmed
METHODS : We performed a retrospective cohort study involving adult patients with UC and CD . - pubmed
When evaluating the subtypes of IBD , there was a significant benefit in time to IBD - related surgery among patients with CD treated with sequentially added combination therapy ( HR 0.46 , 95 % CI 0.25 - 0.85 ) but not UC ( HR 0.82 , 95 % CI 0.30 - 2.22 ) . - pubmed
Improving prevention and care for HIV and sexually transmitted infections among men who have sex with men in Cambodia : the sustainable action against HIV and AIDS in communities ( SAHACOM ) . - pubmed
To address this issue , KHANA , the largest national HIV organization in the country developed and implemented the Sustainable Action against HIV and AIDS in Communities ( SAHACOM ) project . - pubmed
Eccrine Syringofibroadenoma in a Patient with Long - Standing Exfoliative Dermatitis . - pubmed
OBJECTIVE : This study aimed to verify the effectiveness of the sound generator ( SG ) associated with the counseling in the treatment of the tinnitus in individuals with and without hearing loss regarding the improvement of the nuisance through Tinnitus Handicap Inventory ( THI ) and Visual Analogue Scale ( VAS ) . - pubmed
CONCLUSION : The use of the SG was similarly effective in the treatment of the tinnitus in individuals with and without hearing loss , causing an improvement of the nuisance and handicap . - pubmed
This retrospective study reviewed the patients treated by MMA for OSAS between 1995 and 2009 . - pubmed
CONCLUSIONS : MMA is an effective and stable treatment of OSAS in selected patients . - pubmed
Modeling Down Syndrome in Mice . - pubmed
Listeria monocytogenes , a bacterium that is responsible for listeriosis , is a very diverse species . - pubmed
PURPOSE : Recurrent diverticulitis has been reported in 30 - 50 % of patients who recover from an episode of diverticular - associated abscess . - pubmed
Our aim was to review the outcomes of patients who underwent non - operative management after percutaneous drainage ( PD ) of colonic diverticular abscess . - pubmed
Among the remaining 73 patients , there were no significant differences in demographics or abscess variables compared to those who underwent elective surgery within 4 months . - pubmed
Only 7 of 73 patients had documented episodes of recurrences , while 22 patients later had elective surgery ( 1.1 + - 1.2 years from the index case ) . - pubmed
This article presents an unusual case of congenital subcutaneous hamartoma of incisive papilla in a 2 - year - old female child causing feeding and breathing difficulty . - pubmed
The last few decades have witnessed a tremendous advancement in understanding the genetic basis of major human diseases such as cancer . - pubmed
Dermatomyositis Induced by Hepatitis B Virus - related Hepatocellular Carcinoma : A Case Report and Review of the Literature . - pubmed
We herein report the case of a 55 - year - old man with chronic hepatitis B and alcoholism who presented with skin rash . - pubmed
We therefore diagnosed the patient with HCC - induced dermatomyositis . - pubmed
Chemical Constituents of Propolis from Vietnamese Trigona minor and Their Antiausterity Activity against the PANC-1 Human Pancreatic Cancer Cell Line . - pubmed
The ethanol extract of propolis from the Vietnamese stingless bee Trigona minor possessed potent preferential cytotoxicity against PANC-1 human pancreatic cancer cells in nutrient - deprived medium , with a PC50 value of 14.0 mug / mL. - pubmed
Among the isolated compounds , 23 - hydroxyisomangiferolic acid B ( 5 ) and 27 - hydroxyisomangiferolic acid ( 13 ) exhibited the most potent preferential cytotoxicity against PANC-1 human pancreatic cancer cells under nutrition - deprived conditions , with PC50 values of 4.3 and 3.7 muM , respectively . - pubmed
CONCLUSIONS : Although STER failed to achieve en bloc resection in 21.3 % patients , it was still an effective therapy owing to low residual rate and no recurrence rate after piecemeal resection . - pubmed
We immunized guinea pigs with trichloroethylene using the Guinea Pig Maximization Test ( GPMT ) and scored the inflammation on the guinea pigs ' skin . - pubmed
SUBJECTS AND METHODS : A total of 232 patients with RAOU and 123 healthy controls ( HCs ) were enrolled in this study . - pubmed
The patients were divided into 2 groups based on the presence ( BD+ : n = 62 ) or absence of BD ( BD- , n = 170 ) . - pubmed
Nomogram for prediction of level 2 axillary lymph node metastasis in proven level 1 node - positive breast cancer patients . - pubmed
BACKGROUND : The current management of the axilla in level 1 node - positive breast cancer patients is axillary lymph node dissection regardless of the status of the level 2 axillary lymph nodes . - pubmed
The goal of this study was to develop a nomogram predicting the probability of level 2 axillary lymph node metastasis ( L-2 - ALNM ) in patients with level 1 axillary node - positive breast cancer . - pubmed
MATERIALS AND METHODS : We reviewed the records of 974 patients with pathology - confirmed level 1 node - positive breast cancer between 2010 and 2014 at the Liaoning Cancer Hospital and Institute . - pubmed
CONCLUSIONS : Our nomogram could help predict L-2 - ALNM in patients with level 1 axillary lymph node metastasis . - pubmed
Since the initial documentation of IgG4 - related disease in patients with autoimmune pancreatitis in 2001 , a growing body of evidence has been accumulating to suggest that various - virtually all - organs can be affected by IgG4 - RD . - pubmed
[ Expression and prognostic value of memory T lymphocyte in patients with non - small cell lung cancer following radiotherapy ] . - pubmed
OBJECTIVE : To investigate the expression and prognostic value of memory T lymphocyte in patients with non - small cell lung cancer(NSCLC ) following radiotherapy . - pubmed
METHODS : Forty - six patients with NSCLC receiving radiotherapy in Ningbo Medical Center Lihuili Hospital from February 2010 to May 2012 were enrolled in the study and 50 healthy subjects served as the control group . - pubmed
CONCLUSIONS : NSCLC patients show a significant immunosuppression at the initial stage after radiotherapy , and then a gradual improvement . - pubmed
Patients with emergency intubation following trauma were eligible for inclusion . - pubmed
Predictors of enophthalmos among adult patients with pure orbital blowout fractures . - pubmed
Of the 629 patients with orbital fractures , 87 were pure orbital blowout fractures . - pubmed
One case was observed in a 43 - year - old man with a history of recurrent pneumothorax who developed pneumothorax after the surgical biopsy . - pubmed
A 25 - year - old woman presenting with auditory hallucinations was referred to A hospital for examination and treatment . - pubmed
Immunologically , PRRSV - susceptible mononuclear cells are the first line of defense against microbial infection and responsible for antigen recognition , processing , and presentation to T and B cells ; a critical step in the initiation and development of an effective adaptive immune . - pubmed
Thus , impairment of normal immune function renders the host less able to resist and/or eliminate secondary infectious agents and partially explains the synergy between PRRSV and bacterial and viral co - infections . - pubmed
Multinomial logistic regression quantified sociodemographic and HIV - treatment factors associated with incident microcytic anemia or ACD over 18 months . - pubmed
We report the case of a 47 - year - old man who had hemoptysis due to a lung parenchymal injury after nail gun use . - pubmed
BACKGROUND : Cancer - related fatigue ( CRF ) is one of the most troubling symptoms of cancer patients during chemotherapy , and no gold standard for the treatment of CRF has been established . - pubmed
OBJECTIVE : This study aimed to examine the effects of the Baduanjin qigong on patients with colorectal cancer and CRF , and to explore its intervention effects . - pubmed
Ninety patients with chemotherapy - treated colorectal cancer and CRF were randomized to a Baduanjin exercise group or a routine care group . - pubmed
At 24 weeks , the proportion of patients with moderate - to - severe CRF was significantly smaller in the exercise group than in the control group ( 23.2 vs. 59.1 % , p & lt ; 0.01 ) . - pubmed
CONCLUSIONS : Baduanjin qigong exercise can relieve CRF in patients with colorectal cancer undergoing chemotherapy and can improve their physical activity level and their quality of sleep . - pubmed
The aims of this study were to ( 1 ) evaluate the sleep quality in OSA patients with obesity and ( 2 ) identify the parameters most related to sleep quality in OSA patients with obesity . - pubmed
METHODS : Of the patients with polysomnography ( PSG ) , OSA patients with obesity ( body mass index [ BMI ] & gt;=25 ) were enrolled and then divided into 2 groups based on the Pittsburg Sleep Questionnaire Index ( PSQI ): patients with good sleep quality ( PSQI & lt;=5 , good sleepers ) and those with poor sleep quality ( PSQI & gt;5 , poor sleepers ) . - pubmed
In addition , we enrolled OSA patients without obesity as a disease control group . - pubmed
OBJECTIVE : We report the immune response during a case of acute HEV response in a patient with an acute hepatitis E virus ( HEV ) genotype 3 infection in the Netherlands . - pubmed
RESULTS : The patient initially presented with features typical of acute viral hepatitis , with detectable HEV RNA in blood . - pubmed
Real time PCR revealed the presence of HEV in liver tissue , suggestive of active intrahepatic infection despite clearance in blood . - pubmed
CONCLUSIONS : Our results support utility of cobas tissue and plasma testing to aid selection of patients with EGFRm advanced NSCLC for first - line osimertinib treatment . - pubmed
Methods : We conducted a web - based questionnaire survey of 654 19- to 39 - year - old adults who had companion dogs in Seoul , South Korea , where a major health burden is depression among young adults . - pubmed
We measured the owners ' attitudes toward their dogs using the modified Pet Attitude Scale ( PAS - M ) and their depression symptoms using the short version of the Center for Epidemiologic Studies depression scale ( CESD-10 ) . - pubmed
We present our experience during 5 years , in which we treated 245 patients with AML , of which we could genetically characterize 48 cases ( 26 females , 22 males ) with a median age of 52 years . - pubmed
OBJECTIVES : The objective of our study was to assess attention processes and executive function in patients with narcolepsy with cataplexy ( NT1 ) . - pubmed
METHODS : We studied 28 patients with NT1 and 28 healthy control participants matched for age , gender , and educational level . - pubmed
RESULTS : Patients had significantly more daytime sleepiness than controls . - pubmed
A significant negative correlation between depression and disease duration was found in NT1 patients . - pubmed
We emphasized the need to control the influence of processing speed and sustained attention in the neuropsychological assessment of NT1 patients . - pubmed
Building upon the development of modern techniques for gene delivery , many gene - based therapies have been effectively used to treat loss - of - function retinal diseases in mice and men . - pubmed
This review article discusses the current indications for PARPIs in both frontline and recurrent settings , current research in combination approaches , and finally , ongoing research on novel methods to target DNA damage response in an effort to exploit the common susceptibility to DNA damage repair in epithelial ovarian cancer and improve outcomes for patients . - pubmed
METHODS : Profiling of the AT lipidome and fasting serum non - esterified fatty acid ( NEFA ) composition were conducted in 125 volunteers ( PNPLA3148MM / MI , n=63 ; PNPLA3148II , n=62 ) . - pubmed
METHODS : A total of 105 patients who received ultrasonography - guided RFA in the Department of Ultrasound , Chinese PLA General Hospital between April 2014 and August 2018 for benign thyroid nodule were enrolled in this retrospective study . - pubmed
METHODS : This was a descriptive register study of all children aged 6 - 14 years with injuries from bicycle accidents who were treated at a Danish university hospital in the 1980 - 2014 period . - pubmed
Timing of Cataract Surgery in Giant Cell Arteritis Patients . - pubmed
METHODS : This retrospective study used ICD-9/10 and Current Procedural Terminology codes to identify all patients with biopsy - proven GCA who underwent cataract surgery from 2005 to 2019 at a single institution . - pubmed
Excluded from the study were patients whose date of biopsy diagnosis or dose of corticosteroids at the time of cataract surgery was unknown . - pubmed
Two patients had a history of arteritic ischemic optic neuropathy . - pubmed
CONCLUSIONS : Cataract surgery appeared safe for GCA patients on varying doses of prednisone at time of surgery at least 7 months from time of biopsy diagnosis . - pubmed
There is a need for a larger cohort of data from neuro - ophthalmologists and cataract surgeons nationally to establish guidelines for safe cataract surgery in GCA patients . - pubmed
METHODS : Ten patients with progressive or refractory cardiogenic shock underwent Impella 5.0 implantation via transcaval access . - pubmed
We performed in vivo mosaic transgenesis assays in zebrafish to quantitatively test the enhancer activity of type 2 diabetes - associated loci Six out of ten tested sequences are endocrine pancreatic enhancers . - pubmed
Total number of hospital admitted HF patients as well as new - onset or readmitted HF patients decreased by 16 , 13 , and 20 % , respectively ( p < .0001 ) . - pubmed
These studies demonstrate that not only was recapitulation of mechanistic activity supported in zebrafish , but highly relevant off - target toxicities observed in higher vertebrates were identified in zebrafish , regardless of chorionation . - pubmed
Deep anterior lamellar keratoplasty with cross - linked acellular porcine corneal stroma to manage fungal keratitis . - pubmed
One patient developed fungal reinfection and underwent penetrating keratoplasty . - pubmed
High output HF was surgically induced via creation of an arterio - venous fistula in adult male Sprague - Dawley rats . - pubmed
Typhimurium , involved in human infection outbreaks , should be considered a potential risk for consumers . - pubmed
Anatomical tracing , chemogenetic , optogenetic and local pharmacological approaches were utilized to investigate the participation of the LPB - l / vlPAG pathway in itch and pain sensation in mice . - pubmed
MATERIALS AND METHODS : This prospective study included patients with clinically suspected CaP that were referred to MRI - fusion biopsy from 2014 to 2019 . - pubmed
Overall cancer detection rate was higher in patients with a positive DRE ( 70.3 % vs 48.9 % , P < 0.05 ) . - pubmed
BACKGROUND / AIMS : This study aimed to evaluate the real - life efficacy and tolerability of direct - acting antiviral treatments for patients with chronic hepatitis C ( CHC ) with / without cirrhosis in the Turkish population . - pubmed
MATERIAL AND METHODS : A total of 4,352 patients with CHC from 36 different institutions in Turkey were enrolled . - pubmed
CONCLUSION : LDV / SOF or PrOD +- RBV were effective and tolerable treatments for patients with CHC and with or without advanced liver disease before and after liver transplantation . - pubmed
Although HCV eradication improves the liver function , there is a risk of developing HCC . - pubmed
[ Adrenal phlebography in 35 women with pilary virilism . - pubmed
In a patient with documented paroxysmal junctional tachycardia ( PJT ) electrophysiologic studies were performed using an extrastimulus technique . - pubmed
Postural changes in blood pressure were recorded in all 391 patients suffering from Parkinson ' s syndrome over a period of six years . - pubmed
Histological examination of the entire central nervous system and the sympathetic ganglia was performed in six patients suffering from idiopathic Parksinson ' s disease . - pubmed
Five of the six patients had Lewy bodies in the sympathetic ganglia . - pubmed
Loss of nerve cells was noted in the sympathetic ganglia in those patients that demonstrated postural hypotension . - pubmed
Strains ( 115 ) of Bacteroides fragilis were identified at the subspecific level and were tested for susceptibility to ampicillin , cephalothin , chloramphenicol , clindamycin , penicillin , and tetracycline using an agar dilution technique . - pubmed
We tested the following strains : B. - pubmed
One strain of B. - pubmed
Mouse mammary tumor virus ( MMTV ) is a milk - transmitted retrovirus involved in the neoplastic transformation of mouse mammary gland cells . - pubmed
A patient treated for ovarian epithelial cancer by total abdominal hysterectomy ( TAH ) , bilateral salpingo - oophorectomy ( BSO ) , total omentectomy and five courses of single agent carboplatin chemotherapy , developed retroperitoneal fibrosis . - pubmed
The protocol asked for volunteers , epileptic cases and patients with Alzheimer ' s disease . - pubmed
The retrospective analysis has concerned 323 patients with acute nonlymphocytic leukaemia ( ANLL ) . - pubmed
The comparable patients groups were treated since 1981 according to protocols used by the Polish Acute Leukaemia Group ( induction ; modified TAD or Adriamycin plus Ara - C , maintenance ; rotatingly changed polychemotherapy for 3 years ) . - pubmed
The scoring system has been elaborated allowing selection of ANLL patients to standard risk group and a high risk group . - pubmed
[ Pathology of the gastrointestinal tract in patients with reactive arthritis and its possible role in the pathogenesis of the disease ] . - pubmed
It presents in older patients as a mass lesion and usually remains localized . - pubmed
Twelve patients with conjunctival lymphoma were treated at the Massachusetts General Hospital between 1979 and 1988 . - pubmed
Two of 12 patients were found to have systemic disease at the time of presentation . - pubmed
One patient developed conjunctival lymphoma 5 years after the diagnosis of generalized disease . - pubmed
One of 12 patients died of systemic disease 4 years after treatment of the ocular lesion . - pubmed
Two patients developed cataracts 4 and 5 years after treatment ; one had bilateral cataract , although only one eye had been treated . - pubmed
The effects of intraarterial chemotherapy with cisplatin on rabbit VX2 carcinoma transplanted to the hind legs of animals were studied . - pubmed
The author concludes that significant ultrastructural changes can be demonstrated by the regional administration of cisplatin in rabbit VX2 carcinoma and that these promising results should be followed by clinical trials . - pubmed
A histomorphometric analysis of trephine biopsies of bone marrow from 65 patients with chronic myeloid leukemia . - pubmed
A histomorphometric ( planimetric ) study was performed on trephine biopsies of the bone marrow taken at presentation from 65 patients ( 31 males and 34 females , with a median age of 48 years ) with chronic myeloid leukemia ( CML ) . - pubmed
Specimens from 20 patients ( 9 males and 11 females , with a median age of 53 years ) without any hematologic disorders served as controls . - pubmed
The CML patients were separated into two groups with different survival patterns . - pubmed
Seven patients reported an improvement in the level of fatigue , the partial pressure of carbon dioxide fell significantly ( 6.5 + /- 0.9 to 6.1 + /- 0.9 kPa : P less than 0.01 ) and there was a slight bronchodilator effect [ forced expiratory volume in 1s ( FEV1 ) 0.60 + /- 0.18 to 0.71 + /- 0.2 1s-1 : P less than 0.02 ] after 6 months . - pubmed
The drug was generally well tolerated but three patients with pre - existing biliary tract disease developed obstructive jaundice . - pubmed
We tested if specific inhibition of recruitment of leukocytes across the blood brain barrier from the vascular compartment to the cerebrospinal fluid ( CSF ) space reduced tissue damage and improved the outcome of infection in a rabbit model of experimental meningitis . - pubmed
Animals receiving the antibody experienced a delay in the development of bacteremia and a significantly reduced inflammatory response during ampicillin - induced bacterial killing . - pubmed
Alveolar echinococcosis , a serious and often fatal human disease , can be efficiently cured only by complete surgical resection of the Echinococcus multilocularis lesion . - pubmed
Six of 7 additional patients who showed recurrences in an average of 6 years after surgery despite assumed complete surgical resection , were positive by Em2 - ELISA at the time of recurrence . - pubmed
[ Lipid peroxidation in the etiology of sudden death and the mechanisms of its activation in the myocardium of patients with ischemic heart disease ] . - pubmed
Comparison of cefotaxime , imipenem - cilastatin , ampicillin - gentamicin , and ampicillin - chloramphenicol in the treatment of experimental Escherichia coli bacteremia and meningitis . - pubmed
Pathological changes in the teeth and tooth appendages of the rat in radiation sickness . - pubmed
The records of 104 patients with primary adenocarcinoma of the duodenum were reviewed . - pubmed
Regulation of alternative pathways of glucose metabolism in rat heart in alloxan diabetes : changes in the pentose phosphate pathway . - pubmed
The flux of glucose through the pentose phosphate pathway , important in relation to the provision of ribose 5 - phosphate for nucleotide and RNA synthesis , was decreased by 70 % in the diabetic rat heart in parallel with a similar decreased flux through the glycolytic route . - pubmed
We report an infant with classical phenylketonuria ( PKU ) who had unusually high serum phenylalanine at 12 days of life ( 5200 mumol ; greater than 3.2 SD above our mean for PKU at 10 - 15 days of age ) while on parenteral nutrition , despite a relatively high tolerance for phenylalanine on oral feeds at 3 - 4 months of life ( 97 - 128 mg / kg / day ; normal for PKU : less than 90 mg / kg / day ) . - pubmed
Identification of PKU was somewhat delayed in this child because of failure to recognize that parenteral nutrition provides a phenylalanine load equivalent to or greater than the routine oral formula feeding . - pubmed
This study demonstrates that significant baroreflex - mediated regulation of vasopressin can occur in humans in the absence of overt hypotension . - pubmed
[ Correlation of noninvasive parameters of myocardial function in patients with postinfarction cardiomyopathy ] . - pubmed
A comparison of breathing pattern between transient and steady state hypoxia in awake dogs . - pubmed
Computerized tomographic scan findings in patients with autistic behavior . - pubmed
An analysis of the computerized tomography scans of 17 patients with autistic behavior was carried out by investigators independent from those selecting the subjects . - pubmed
Useful determinants of prognosis for patients with metastatic cancer of the stomach . - pubmed
Pretreatment absolute granulocyte ( less than 6,000 / cu mm ) , lymphocyte ( greater than 1,500 / cu mm ) , and monocyte ( 300 to 900 / cu mm ) counts are three independent indicators of good prognosis for patients with metastatic gastric cancer . - pubmed
Serum and peripheral blood lymphocytes from 10 patients with Crohn ' s disease and 10 healthy subjects were examined for immunological reactivity against chick embryo cell cultures displaying cytopathic effects after inoculation with 0.2 micro filtrates prepared from Crohn ' s disease intestinal tissues . - pubmed
The clinical trial indicated that both algorithms were fairly comparable and that their primary use would be as teaching aids for medical students and residents to suggest various diagnostic possibilities for hypercalcemia in patients . - pubmed
A group of patients with portal - systemic encephalopathy were studied . - pubmed
The effects of zinc deficiency on oral behaviour and taste bud morphology in chicks . - pubmed
PURPOSE : To evaluate the prevalence of autoimmune thyroid disease and thyroid dysfunction in patients with primary Sjogren ' s syndrome . - pubmed
PATIENTS AND METHODS : Thyroid function of 33 patients with primary Sjogren ' s syndrome was clinically and biochemically evaluated . - pubmed
CONCLUSIONS : The high prevalence of autoimmune thyroid disease and thyroid dysfunction found in primary Sjogren ' s syndrome , using sensitive immunologic and thyroid function tests , suggest that both diseases are more frequently associated than it was previously thought , and should be sought clinically and by laboratory tests in all patients with primary Sjogren ' s syndrome . - pubmed
Bullous congenital ichthyosiform erythroderma is a human hereditary skin disorder in which suprabasal keratinocytes rupture . - pubmed
Pityrosporum ovale in healthy children , infantile seborrhoeic dermatitis and atopic dermatitis . - pubmed
Twenty children with ISD and twenty healthy infants were subjected to culture for P. - pubmed
ovale cultures in 60 patients with AD , 40 patients with rhinoconjunctivitis and/or asthma ( RA ) and 40 children and young adults with no atopic history ( HC ) . - pubmed
ovale was evaluated with a skin prick test ( SPT ) and RAST and compared in 3 groups ( AD , RA , HC ) of patients aged 0 - 20 years . - pubmed
In patients with AD on different parts of the body , 15 % had a positive SPT to P. - pubmed
In another group of patients , aged 14 - 53 years , with AD localised mainly to the head and neck area , the SPT was positive in 55 % of the patients . - pubmed
A prospective study of 21 patients with the diagnosis of non - alcoholic steatohepatitis ( NASH ) was carried out . - pubmed
18 patients were obese , 2 of them diabetic , 2 others had a history of exposure to drugs ( amiodarone and isopropilic alcohol ) and the last one presented hypothyroidism . - pubmed
4 were females out of which one was pregnant during the appearance of brain metastases . - pubmed
Pharmacokinetics and acute cardiovascular effects of menogaril in patients with metastatic tumors . - pubmed
Menogaril ( 200 mg / mg ) was infused over 90 minutes to 4 patients with metastatic colon or prostate cancer . - pubmed
A 58 - year - old man with common variable immunodeficiency , splenomegaly , and hemolytic anemia . - pubmed
Photosensitivity - induced retinal atrophy in albino rat . - pubmed
Pentylenetetrazol elicits epileptiform activity in the dentate gyrus of the urethane anesthetized rat by activation of the entorhinal cortex . - pubmed
In the urethane anesthetized rat , pentylenetetrazol produces a characteristic epileptiform discharge in the dentate gyrus . - pubmed
In other animals tetrodotoxin ( TTX ) was injected into the right entorhinal cortex before the onset of epileptiform activity ( n = 5 ) . - pubmed
Results , principles and pitfalls in the management of renal AA - amyloidosis ; a 10 - 21 year followup of 16 patients with rheumatic disease treated with alkylating cytostatics . - pubmed
OBJECTIVE : To assess renal functional outcome at 10 - 21 years in 16 consecutive patients with rheumatic disease , treated with alkylating agents for secondary renal AA - amyloidosis , and to review management principles developed during 21 years . - pubmed
RESULTS : Of the 7 cases of precipitous uremia that occurred , 4 were not treated with cytostatics at the patients ' local hospitals . - pubmed
They presented with bilateral central predescemetic avascular haze associated with mild corneal stromal edema , descemetic folds in one patient and polymegethism on endothelial specular microscopic examination . - pubmed
The vision impairment was severe , unilateral in one patient and bilateral in the other . - pubmed
PURPOSE : We evaluated the safety and efficacy of a new transfusion regimen for children with severe anemia . - pubmed
Throughout the transfusion , the patients were closely monitored for any clinical signs of heart failure . - pubmed
RESULTS : No patient developed any signs of cardiac failure or increase in the heart rate during or after the completion of transfusion . - pubmed
Excluding the four patients with sickle cell anemia , the remaining 18 patients had a mean increase in the hematocrit of 1.04 % per 1 cc / kg of PRBC ( range 0.85 - 1.28 ) . - pubmed
CONCLUSION : We conclude that for children with severe anemia of gradual onset requiring transfusion therapy , continuous transfusion of PRBC at the rate of 2 cc / kg / h is a safe and effective regimen resulting in an increase in the hematocrit of approximately 1 % for each 1 cc / kg of PRBC transfused in all patients , except patients with sickle cell anemia . - pubmed
Multiple cutaneous mast cell tumours in a cow . - pubmed
Criteria for abnormal SAE in children classified according to age were filtered QRS duration ( f - QRSd ) & gt ; 95 msec , root mean square ( RMS ) & lt ; 30 mu v and duration of low amplitude signal ( LAS ) & gt ; 25 msec in those under 3 months old ; f - QRSd & gt ; 110 msec , RMS & lt ; 25 mu v , LAS & gt ; 30 msec in those 3 months or more but less than 1 year old ; f - QRSd & gt ; 115 msec , RMS & lt ; 20 mu v , LAS & gt ; 30 msec in those 1 year old or more but less than 12 year old ; and f - QRSd & gt ; 125 msec , RMS & lt ; 20 mu v , LAS & gt ; 30 msec in those 12 year old or more . - pubmed
Reduction of brain injury using heparin to inhibit leukocyte accumulation in a rat model of transient focal cerebral ischemia . - pubmed
They evaluated the efficacy of sulfated polysaccharides ( unfractionated heparin , low - molecular - weight heparin , heparan sulfate , chondroitin sulfate C , and dextran sulfate ) on leukocyte accumulation , infarction size , and neurological outcome after transient focal cerebral ischemia in rats subjected to 1 hour of ischemia and 48 hours of reperfusion . - pubmed
Ibotenic acid lesions of the superior colliculus produce longer lasting deficits in visual orienting behavior than aspiration lesions in the cat . - pubmed
Four animals with aspiration lesions initially showed an hemianopia in the contralateral hemifield which recovered fully in 4.5 weeks or less . - pubmed
In these animals the contralateral hemianopia persisted for an average of 16.6 weeks , but may have persisted longer had we not intervened by either sacrificing the animal or ablating the visual cortex contralateral to the SC lesion . - pubmed
Forty - one distal femora , from human cadavers with a mean age of 45 years ( range : 23 to 70 years ) at the time of death were studied . - pubmed
We administered rhSOD1 as an acute bolus in three sheep and 16 human subjects with amyotrophic lateral sclerosis ( ALS ) . - pubmed
administration of 20 micrograms of rhSOD1 in ALS subjects revealed a mean elimination half - life of 2.2 + /- 0.8 hours , clearance of 1.2 + /- 0.6 ml per hour , and volume of distribution of 3.5 + /- 0.4 ml . - pubmed
We detected no benefit of this treatment in the two patients with familial ALS . - pubmed
Human non - small - cell lung cancer ( NSCLC ) is considered to be a chemotherapy - refractory malignancy . - pubmed
STUDY DESIGN : Invasive cervical cancer was diagnosed in 12 pregnant women between 1 January 1977 and 1 January 1996 . - pubmed
Ten patients had FIGO ( International Federation of Gynaecology and Obstetrics ) stage IB lesions , two patients stage IIA / B. - pubmed
Eight patients had squamous cell carcinoma , four adenocarcinoma . - pubmed
Two patients , one in each group , died after a relapse . - pubmed
CONCLUSION : Delayed treatment to achieve greater fetal maturity is a reasonable option for patients with cervix carcinoma of & lt;stage IIB , non - bulky tumours and a gestation of & gt;20 weeks . - pubmed
PATIENTS AND METHODS : Parenchymal function was assessed by quantitative salivary gland scintigraphy performed prospectively in 50 patients with differentiated thyroid cancer before and 3 months after HD - RIT with either 3 GBq iodine ( ( 131 ) I ) ( n=21 ) or 6 GBq ( 131 ) I ( n=29 ) in a double - blind , placebo - controlled study . - pubmed
Nine control patients developed grade I and two grade II xerostomia . - pubmed
Three months after HD - RIT , parenchymal function of salivary glands was not significantly altered ( P=.691 ) and xerostomia did not occur in any of these patients . - pubmed
CONCLUSION : Parenchymal damage in salivary glands caused by HD - RIT can significantly be reduced by amifostine , which may improve the quality of life of patients with differentiated thyroid cancer . - pubmed
HYPOTHESIS : There is no difference in the effects produced in patients suffering from smooth bronchiolar muscle spasm by metaproterenol when delivered either by a standard metered - dose inhaler or with a hand - held nebulizer . - pubmed
PARTICIPANTS : Consecutive prehospital patients complaining of difficulty breathing with clinical evidence of bronchospasm and with a history of asthma , chronic obstructive pulmonary disease , or emphysema who were not in extremis . - pubmed
Human immunodeficiency virus type 2 ( HIV-2 )- infected baboons ( Papio cynocephalus ) provide a valuable animal model for the study of acquired immunodefidency syndrome ( AIDS ) pathogenesis since many features of disease progression resemble HIV-1 - infection of humans . - pubmed
Effects of chelator treatment on aorta and corpus cavernosum from diabetic rats . - pubmed
The aim was to evaluate the effects of treatment with the transition metal chelator trientine on endothelium - dependent relaxation of aorta and corpus cavernosum from streptozotocin - induced diabetes of 8 weeks duration in rats . - pubmed
Reversal treatment ( 4 weeks untreated diabetes , 4 weeks trientine ) did not effect endothelium - dependent relaxation compared with aortas from rats with 4 weeks of diabetes , however , there was a 22.5 + /- 6.2 % improvement compared with 8 weeks of diabetes . - pubmed
The purpose of this study was to determine whether a viability threshold could be identified from this measure in patients with acute myocardial infarction treated in a homogeneous manner with successful reperfusion therapy . - pubmed
METHOD AND RESULTS : The study group consisted of 61 patients with acute myocardial infarction with a risk area of & gt;6 % LV treated with primary angioplasty between 120 and 240 minutes after symptom onset . - pubmed
Infarct location was anterior in 22 and inferior in 39 patients . - pubmed
MAR was 33+/-15 % LV and IS was 13+/-15 % LV : 23 patients had no infarction despite MAR similar to those with infarction . - pubmed
Receiver - operator characteristic curve analysis identified a nadir value of 0.26 as providing the best separation of patients with and without infarction ( sensitivity , 74 % ; specificity , 74 % ) . - pubmed
Cognitive improvement following rehabilitation in patients with COPD - pubmed
Hypermagnesemia in a pediatric patient . - pubmed
This case report describes an accidental overdose of magnesium that occurred in an 18 - month - old girl during a routine operation . - pubmed
The patient recovered without neurological deficits . - pubmed
Furthermore , histopathological study of the livers of immunized mice showed that granulomas formed around eggs were diminished in both size and number . - pubmed
Inhaled vs oral steroids for adults with chronic asthma . - pubmed
OBJECTIVES : To determine therapeutically equivalent doses of inhaled versus oral steroids for adults with chronic asthma . - pubmed
SELECTION CRITERIA : Randomised controlled trials were selected of at least 4 weeks duration and included patients over the age of 15 years with chronic asthma . - pubmed
Essential role of neutrophils in the initiation and progression of a murine model of rheumatoid arthritis . - pubmed
Neutrophils are prominent participants in the joint inflammation of human rheumatoid arthritis ( RA ) patients , but the extent of their role in the inductive phase of joint inflammation is unknown . - pubmed
In the K / BxN mouse RA model , transfer of autoreactive Ig from the K / BxN mouse into mice induces a rapid and profound joint - specific inflammatory response reminiscent of human RA . - pubmed
We observed that after K / BxN serum transfer , the earliest clinical signs of inflammation in the ankle joint correlated with the presence of neutrophils in the synovial regions of recipient mouse ankle joints . - pubmed
Mice were treated with a neutrophil - depleting mAb before and following transfer of arthritogenic serum and scored for clinical indications of inflammation and severity of swelling in ankle joints and front paws . - pubmed
[ Evaluation of immunity against Venezuelan equine encephalitis virus and dengue in the human population of San Carlos , the Almirante Padilla Island Municipality , Zulia State , Venezuela . - pubmed
During the last epidemic outbreak ( 1995 ) , the studies reported a great number of cases of VEE in humans , based on epidemiologic - clinical diagnosis ; occupying this municipality , the first place in the attack rate by the virus . - pubmed
Given the fact that simian immunodeficiency virus ( SIV ) infection in rhesus macaque is a well - characterized model for human immunodeficiency virus ( HIV ) , it is of great interest to develop an efficient protocol to transduce rhesus macaque primary T cells . - pubmed
We examined 170 patients with acute viral hepatitis B ( AVH - B ) and 10 patients with chronic hepatitis B ( CH - B ) exacerbation . - pubmed
METHODS : Of 354 patients who underwent a TEE study in our laboratory during the study period , 106 were referred for detection of a source of embolism . - pubmed
Protruding arch atheromas were present in 42 patients ( 47 % ) and absent in 47 ( 53 % ) . - pubmed
Nine subjects showed no convulsion . - pubmed
Subjects who showed seizure ( age 37.7 + /- 13.2 years ) were younger ( t = 4.178 , df = 19 , p = 0.00025 , one - tailed ) than those who did not ( age 57.6 + /- 6.1 years ) . - pubmed
The aim of the present study was to evaluate long - term efficacy of a patient education programme in an asthma out - patient clinic . - pubmed
Of 1024 human cancer - focused genes arrayed , 187 genes were up - regulated and 72 genes were down - regulated at least 2 - fold by DC . - pubmed
These bradyzoites did not appear to be functionally mature ; they did not induce patent infections in dogs . - pubmed
Respiratory tract infections caused by Bordetella pertussis are occasionally accompanied by severe neurologic disorders and encephalopathies . - pubmed
These findings support the existence of numerous regulatory mechanisms in the TM and may help explaining the low percentage of glaucoma patients associated with each mutated glaucoma gene . - pubmed
Infection of the upper respiratory tract of the chick with a mild ( vaccine ) strain of Newcastle disease virus : I. Initiation and spread of the infection . - pubmed
A new record of human infection with Dipylidium caninum in the United States . - pubmed
Ultrasound examination of the IOM in 46 forearms from 18 normal volunteers , five patients with restricted forearm pronation and supination , and two preoperative cases was performed to determine the usefulness and reproductivity of this examination . - pubmed
Teloptosis and kenogen : two new concepts in human trichology . - pubmed
Posthypoxic myoclonus ( PHM ) is a syndrome of action and intention myoclonus that occurs in some patients who survive a cardiac arrest . - pubmed
Interventions such as deep brain stimulation that interrupt networks that involve these structures may be useful in patients with severe PHM . - pubmed
OBJECTIVE : To identify the brain regions associated with the cognitive generation of affect in hypomanic bipolar patients . - pubmed
METHODS : The study examined 10 hypomanic female subjects with bipolar affective disorder , and 10 age- and sex - matched comparison subjects using functional magnetic resonance imaging ( fMRI ) while viewing alternating blocks of captioned - pictures designed to evoke negative , positive or no affective change . - pubmed
CONCLUSIONS : This preliminary study suggests that hypomanic patients recruit additional subcortical limbic systems for emotional evaluation when advanced prefrontal cortical processing is no longer sufficient . - pubmed
The patient died of aortic rupture on the 7th postoperative day . - pubmed
Guinea pigs are often used as an animal model of human tuberculosis ( TB ) . - pubmed
However , there are few methods available for pursuing the immunological processes involved in guinea pig TB . - pubmed
We showed that these RT - PCR primer sets could be used to examine mRNA expression semi - quantitatively in guinea pig tissues , and conclude that these newly designed primer sets for conventional RT - PCR will be useful for studying the immunological processes in guinea pig tuberculosis experiments to investigate and evaluate efficacy of new vaccines or anti - mycobacterial drugs . - pubmed
PATIENTS AND METHODS : We report on a female patient who developed keratectasia in both eyes 4 weeks after LASIK . - pubmed
Previously reported non - luminous strains , which had been identified phenotypically as P. - pubmed
Noninvasive ventilation to prevent respiratory failure after extubation in high - risk patients . - pubmed
OBJECTIVE : Compared with standard medical therapy ( SMT ) , noninvasive ventilation ( NIV ) does not reduce the need for reintubation in unselected patients who develop respiratory failure after extubation . - pubmed
PATIENTS : Ninety - seven consecutive patients with similar baseline characteristics , requiring & gt;48 hrs of mechanical ventilation and considered at risk of developing postextubation respiratory failure ( i.e. - pubmed
PURPOSE OF REVIEW : Changes in epidemiology and advances in the treatment of coronary artery disease , hypertension and diabetes mellitus have increased the prevalence of heart failure in the general population , and also the number of patients with heart failure presenting for surgery . - pubmed
Particularly in the perioperative period , patients with chronic heart failure are faced with numerous triggers of acute decompensation that can partly be avoided or treated . - pubmed
Patients without preexisting myocardial contractile dysfunction may sustain severe perioperative complications , e.g. - pubmed
RECENT FINDINGS : Patients with preexisting heart failure undergoing non - cardiac surgery suffer substantial morbidity and mortality despite advances in perioperative care . - pubmed
The importance of heart failure as an independent risk factor is underlined by the fact that patients with coronary artery disease but without heart failure have a similar 30 - day mortality rate to the general population . - pubmed
Streptococcus pyogenes is a Gram - positive bacterium that causes several diseases , including acute tonsillitis and toxic shock syndrome . - pubmed
RECENT FINDINGS : The incidence of POF is increasing largely due to improved survival rates of cancer patients treated with radiation and chemotherapy . - pubmed
For patients with extracapsular extension , the survival curves separate depending on whether positive or negative surgical margins are obtained . - pubmed
CASE : We report on a 30 - year - old woman who desired to preserve her fertility with well - differentiated endometrial adenocarcinoma . - pubmed
In the pathogenesis of a variety of adult human diseases such as cancer and cardiovascular disorders , ROS cause an enhancement of tissue injuries . - pubmed
Primary classic penile Kaposi ' s sarcoma in an elderly HIV - negative patient : report of a case and review of the literature . - pubmed
Firstly , we induced chromosomal breaks in the offspring of a 5H addition line of common wheat carrying a gametocidal chromosome and cytologically screened for plants with structural chromosomal changes involving 5H , such as deletions and translocations . - pubmed
Acute thrombosis in native arterio - venous fistulae ( AVF ) results in considerable patient morbidity . - pubmed
Between 1992 - 2000 , 21 episodes of acutely thrombosed AVF in 15 patients ( 9 females ; age range 29 - 80yrs ) were referred for intervention . - pubmed
Five patients had recurrence of thrombosis & gt;3 months after the primary procedure , 3 had successful reintervention . - pubmed
We describe the case of an elderly woman presenting with syncope , chest pain , electrocardiographic abnormalities , mild enzymatic release , and transient left ventricular apical ballooning , mimicking an anterior wall acute coronary syndrome with shock , following a subarachnoid haemorrhage that could not be detected upon admission . - pubmed
METHODS : Hypersplenism was assessed in 84 consecutive cirrhotic patients attending a university hospital liver clinic . - pubmed
RESULTS : Hypersplenism was present in 78 % of patients and severe in 39 % . - pubmed
Severe hypersplenism was more common in patients with cystic fibrosis liver disease ( 88 % , P & lt ; 0.0001 ) and autoimmune hepatitis ( 60 % , P = 0.0006 ) compared to alcoholic cirrhosis ( 12 % ) . - pubmed
There was a significant correlation between patient age and platelet count r = 0.525 , P & lt ; 0.0001 in the group as a whole and for the sub - group of patients with autoimmune hepatitis r = 0.54 , P = 0.047 . - pubmed
CONCLUSION : Younger patients had lower platelet counts , larger spleens and a higher incidence of hypersplenism suggesting that hypersplenism is significantly related to the age of onset of chronic liver disease . - pubmed
High - resolution / high - contrast MRI of human articular cartilage lesions . - pubmed
Hiding in the shadows of the HIV epidemic : obesity and hypertension in a rural population with very high HIV prevalence in South Africa . - pubmed
Structural and quantitative comparison of cerebrospinal fluid glycoproteins in Alzheimer ' s disease patients and healthy individuals . - pubmed
A quantitative comparison of gel - separated glycoprotein isoforms from twelve AD patients and twelve control subjects was performed with glycoprotein - specific and total protein stains . - pubmed
We have also compared glycoforms in pooled CSF obtained from AD patients and control subjects with mass spectrometry . - pubmed
An outbreak of chlamydiosis in farmed Indopacific crocodiles ( Crocodylus porosus ) . - pubmed
An outbreak of chlamydiosis was diagnosed in hatchling and juvenile Indopacific crocodiles ( Crocodylus porosus ) on a crocodile farm in Papua New Guinea . - pubmed
This case report discusses an unusual presentation of left atrial myxoma in an elderly patient . - pubmed
Different patterns of neuronal activation and neurodegeneration in the thalamus and cortex of epilepsy - resistant Proechimys rats versus Wistar rats after pilocarpine - induced protracted seizures . - pubmed
PURPOSE : To analyze cellular mechanisms of limbic - seizure suppression , the response to pilocarpine - induced seizures was investigated in cortex and thalamus , comparing epilepsy - resistant rats Proechimys guyannensis with Wistar rats . - pubmed
METHODS : The trial involved 50 eyes of 48 patients with medically uncontrolled primary and secondary open - angle glaucoma , randomized to undergo either VDSCI procedure ( 25 eyes ) or DSCI procedure ( 25 eyes ) . - pubmed
[ Effects of central endocannabinoid system on visceral hyposensitivity induced by rapid eye movement sleep deprivation : experiment with rats ] . - pubmed
Laparoscopic repair of Morgagni hernia in an adult : use of a porcine small intestine submucosa biocompatible prosthesis . - pubmed
We report a case of successful laparoscopic repair of a very large symptomatic Morgagni hernia in a 78 - year - old patient , treated by positioning a gradually resorbable mesh made from porcine SIS ( Surgisis Soft Tissue Graft device -- Cook Inc , Bloomington , Ind ) . - pubmed
METHODS : Observational case report of a patient who self - inflicted bilateral scleral lacerations with a razor blade , after losing his job . - pubmed
RESULTS : The patient sustained bilateral inferior scleral perforations , with hypotony and a right traumatic cataract . - pubmed
CONCLUSION : Self - inflicted ocular injury may be possible in non - psychotic patients , as a situational response to a life event . - pubmed
The purpose of this retrospective study was to evaluate the clinical and radiographic results of a curved periacetabular osteotomy for the treatment of developmental dysplasia of the hip in patients fifty years of age or older . - pubmed
METHODS : We evaluated forty - six consecutive hips in forty - two patients fifty years of age or older ( the older group ) who had developmental dysplasia of the hip and had undergone a curved periacetabular osteotomy between 1995 and 2006 with a minimum two - year follow - up period . - pubmed
CONCLUSIONS : Satisfactory results can be obtained clinically and radiographically after curved periacetabular osteotomy in patients fifty years of age or older with Tonnis grade-1 or 2 osteoarthritis of the hip secondary to developmental dysplasia . - pubmed
Is the large size of the pinna of the ear of the European hare ( Lepus europaeus ) due to its role in thermoregulation or in anterior capital shock absorption ? - pubmed
A 68 - year - old man was admitted with intermittent chest tightness . - pubmed
The aim was to evaluate their relative value for the control of ovine cutaneous myiasis ( sheep blowfly strike ) on farms . - pubmed
Reliability of ultrasonography to detect synovitis in rheumatoid arthritis : a systematic literature review of 35 studies ( 1,415 patients ) . - pubmed
BACKGROUND : Osteoporosis is a major healthcare issue with over 50 % of postmenopausal women suffering an osteoporosis - related fracture . - pubmed
RESULTS : Ninety - six women had a lateral chest X - ray with 53 ( 55 % ) having vertebral fractures . - pubmed
Does objective shoulder impairment explain patient - reported functional outcome ? - pubmed
HYPOTHESIS : Following a healed proximal humerus fracture , patient - reported outcome is predicted by objective physical examination findings . - pubmed
Hematopoietic stem cell transplantation ( HSCT ) offers the opportunity for cure to patients with leukemia , lymphoma and severe non - malignant diseases . - pubmed
This study indicates that estimating inbreeding depression might best be based on the performance data of animals with an equal and sufficiently - large number of ancestral generations known . - pubmed
Ginseng extracts and ginsenosides including Rb1 , Rd , Rg1 , Rg3 , Rh1 , Rh2 , Rh3 and Rp1 have been reported to have anti - inflammatory properties in different studies related to inflammation . - pubmed
Taken together , this summary provides evidences for the anti - inflammatory effects of ginseng extracts and ginsenosides as well as the underlying mechanisms of their effects on inflammatory diseases . - pubmed
METHODS : Six patients with diffuse peritoneal mesothelioma were treated with 6 cycles of pemetrexed ( 500 mg / m2 ) and cisplatin ( 75 mg / m2 ) . - pubmed
A 10 - year review of all patients treated at a pediatric burn center was performed with the goal of identifying the characteristics of patients with GCMN and the outcomes of the treatment provided in a burn center . - pubmed
OBJECTIVE : To determine whether vertebroplasty is more effective than placebo for patients with pain of recent onset ( & lt;= 6 weeks ) or severe pain ( score & gt;= 8 on 0 - 10 numerical rating scale ) . - pubmed
The membrane bearing the spots of the synthesized peptides were incubated with the allergic serum pools consisting of the sera from 5 allergic individuals . - pubmed
baumannii were the common NFGNB isolated in our study from patients of , urinary tract infection , bacteremia , surgical site infections , and ventilator associated pneumonia . - pubmed
METHODS : Data from 52 ulcerative colitis ( UC ) patients with 32 Crohn ' s disease ( CD ) patients were compared . - pubmed
Primary sclerosing cholangitis ( PSC ) was present in 12/84 patients . - pubmed
Glucans from the edible mushroom Pleurotus pulmonarius inhibit colitis - associated colon carcinogenesis in mice . - pubmed
METHODS : In vitro , human colorectal cancer cells were treated with FBE and ME and analyzed for inflammation response , for markers of apoptosis , and for cell - cycle progression . - pubmed
pulmonarius FBE and ME inhibit colitis - associated colon carcinogenesis induced in mice through the modulation of cell proliferation , induction of apoptosis , and inhibition of inflammation . - pubmed
Bisphosphonates combined with sunitinib may improve the response rate , progression free survival and overall survival of patients with bone metastases from renal cell carcinoma . - pubmed
We aimed to evaluate whether bisphosphonates can bring a response rate ( RR ) , progression free survival ( PFS ) and overall survival ( OS ) benefit to patients with bone metastasis from renal cell carcinoma ( RCC ) that is treated with sunitinib . - pubmed
METHODS : We performed a multicentre retrospective study of patients with bone metastases from RCC that was treated with sunitinib . - pubmed
RESULTS : Between 2004 and 2011 , 209 patients with metastatic RCC were treated with sunitinib , 76 had bone metastases , 35 bisphosphonates users and 41 non - users . - pubmed
Plasma sphingosine 1 - phosphate levels and the risk of vertebral fracture in postmenopausal women . - pubmed
PARTICIPANTS : Sixty - nine cases having radiological VF and 69 age- and body mass index - matched controls among 460 eligible postmenopausal women participated in the study . - pubmed
Dexpramipexole effects on functional decline and survival in subjects with amyotrophic lateral sclerosis in a Phase II study : subgroup analysis of demographic and clinical characteristics . - pubmed
Subjects with amyotrophic lateral sclerosis ( ALS ) received dexpramipexole 300 mg / day or 50 mg / day for 24 weeks . - pubmed
The diagnostic evaluation of a patient with dementia . - pubmed
In patients aged 80 or older , more than one cause of dementia is often present , for example , Alzheimer disease plus vascular dementia . - pubmed
A structured clinical approach helps to define the diagnosis and collects information essential for establishing a comprehensive care plan for patients with dementia and their families . - pubmed
In vivo acquired daptomycin resistance during treatment of methicillin - resistant Staphylococcus aureus endocarditis . - pubmed
This clinical case reports the emergence of a daptomycin - resistant Staphylococcus aureus isolate during daptomycin treatment in a patient with right - sided infective endocarditis who had never been treated with vancomycin . - pubmed
Moreover , the proposed method was successfully applied to the crude extracts of traditional Chinese medicine and a marine sponge from which 12 bioactive compounds were screened and characterized based on their anti - oxidative or anti - tumor activities . - pubmed
In particular , two diterpenoid derivatives , agelasine B and ( -)- agelasine D , were identified for the first time as anti - tumor compounds from the sponge Agelas mauritiana , showing a considerable activity toward MCF-7 cells ( IC50 values of 7.84 + -0.65 and 10.48 + -0.84 muM , respectively ) . - pubmed
By experimentally manipulating the intensity of rodent malaria ( Plasmodium berghei ) infections in Anopheles stephensi mosquitoes under different environmental conditions , we show that parasites experience substantial density - dependent fitness costs because crowding reduces both parasite proliferation and vector survival . - pubmed
Finally , the protective effect of intact and EndoS - treated IVIg administered by i.p was studied in a murine model of progressive TB . - pubmed
Although its neurotoxicity has been extensively described , little is known about its ability to strengthen neural circuits when administered in a manner that reproduces human abuse ( i.e. - pubmed
METHODS : From February 2004 to August 2011 , 37 consecutive patients with symptomatic hepatic cysts were evaluated and treated at Dong - A University Hospital . - pubmed
The mean fellow - up was 21 months , and six patients ( 16 % ) experienced radiographic - apparent recurrence . - pubmed
Reoperation due to recurrence was performed in two patients . - pubmed
METHODS : Patients with spinal tuberculosis and healthy volunteers were enrolled between December 2004 and December 2010 . - pubmed
RESULTS : A total of 208 patients with spinal tuberculosis and 210 healthy volunteers were included . - pubmed
Harvesting autologous stem cells from a patient with red blood cell abnormalities of beta - thalassemia intermedia . - pubmed
BACKGROUND : Autologous stem cell transplants in patients with hemoglobinopathies are limited . - pubmed
CONCLUSIONS : Adjustments in apheresis variables allowed successful collection of peripheral blood stem cells from a patient with RBC anomalies of beta - thalassemia that interfered with standard stem cell harvesting . - pubmed
Potential human immunodeficiency virus transmission makes prompt disclosure of child sexual abuse in Africa critical . - pubmed
The number of children reporting child sexual abuse is increasing , possibly because of increasing awareness , availability of services , and fear of HIV . - pubmed
Type 1 diabetes in mice and men : gene expression profiling to investigate disease pathogenesis . - pubmed
Using the nonobese diabetic ( NOD ) mouse model of T1D and the non - disease prone congenic NOD.B10 mice , our laboratory demonstrated striking tissue - specific and age - dependent changes in gene expression during disease progression . - pubmed
Remarkably , both genes were also alternatively spliced in the same tissues of auto - antibody positive prediabetic patients , and these splicing events resulted in similar downstream effects as those seen in NOD mice . - pubmed
CONCLUSION : This study suggests that cinnarizine is safe and effective in reducing both headache and vertigo aspects of " migraine plus vertigo " among the patients who suffer from either vestibular migraine or migraine with brainstem aura associated with vertigo . - pubmed
Toxicity of six plant extracts and two pyridone alkaloids from Ricinus communis against the malaria vector Anopheles gambiae . - pubmed
BACKGROUND : The African malaria vector , Anopheles gambiae s.s . - pubmed
METHODS : We studied by echocardiography and carotid ultrasound 435 asymptomatic patients with metabolic syndrome . - pubmed
Patients with coronary artery disease or more than mild valvular heart disease were excluded . - pubmed
Dengue is an acute febrile illness caused by any of four mosquito - transmitted dengue virus ( DENV ) types . - pubmed
Recent or past infection with a DENV was evident in 93 % ( 13 of 14 ) missionaries with available sera . - pubmed
Polyoxometalates as antitumor agents : Bioactivity of a new polyoxometalate with copper on a human osteosarcoma model . - pubmed
We report herein for the first time , a detailed study of the mechanisms of action of a copper ( II ) compound of the group of HPOMs with the formula K7Na3 [ Cu4 ( H2O ) 2 ( PW9034 ) 2 ] 20H2O ( PW9Cu ) , in a model of human osteosarcoma derived cell line , MG-63 . - pubmed
METHODS : A total of 40 female patients diagnosed with CFS were asked to provide morning saliva cortisol samples ( after awakening , 30min later , and 1h later ) for seven consecutive days as a measure of cortisol activity . - pubmed
In addition , patients were exposed to the Trier Social Stress Test , a well - validated stress test , to investigate the relationship between early childhood trauma and cortisol stress reactivity . - pubmed
Extracorporeal membrane oxygenation ( ECMO ) may be used to support patients with severe hypoxemic respiratory failure refractory to conventional mechanical ventilation . - pubmed
We describe our center 's experience with four patients who received ECMO for refractory hypoxemic respiratory failure due to diffuse alveolar hemorrhage ( DAH ) , a condition for which anticoagulation is typically contraindicated , and provide a review of the literature . - pubmed
The results from this case series , along with previously published data , suggest that ECMO is a reasonable management option for patients with DAH - associated severe , refractory hypoxemic respiratory failure . - pubmed
UNLABELLED : Specific types of human papillomavirus ( HPV ) are strongly associated with the development of cervical carcinoma . - pubmed
These findings shed light on the mechanisms by which HPV induces genomic instability and hold promise for the identification of drug targets . - pubmed
These findings shed light on the mechanisms by which HPV induces genomic instability and hold promise for the identification of drug targets . - pubmed
Initial therapies for newly diagnosed myeloma patients depend on the individual 's clinical condition . - pubmed
Induction therapy with novel agents and high - dose chemotherapy followed by autologous stem cell transplantation is a standard therapy for newly diagnosed younger myeloma patients . - pubmed
are widely used as initial therapy for transplantation - ineligible myeloma patients . - pubmed
RESULTS : Primary outcome was surgical site infection ( SSI ) , and 142 patients were included . - pubmed
The SSI occurred in 22 % of patients in group 1 and in 29 % of patients in group 2 ( P = .39 ; odds ratio : 1.46 confidence interval 95 % : 0.61 - 3.47 ) . - pubmed
We followed up 19,825 patients who survived a first admission for stroke at the age of & gt;= 18 years , among which 3,536 hospitalized cases with stroke recurrence ( ICD-9 - CM codes 430.xx-437.xx ) were identified and individually matched to 6,679 randomly - selected controls . - pubmed
MATERIALS AND METHODS : We retrospectively reviewed 837 patients who underwent RARP for clinically localized prostate cancer without neoadjuvant endocrine therapy . - pubmed
A total of 4 species were identified among the MRCoNS isolates , namely , Staphylococcus sciuri ( 10 strains ) , Staphylococcus lentus ( 6 strains ) , Staphylococcus cohnii ( 3 strains ) and Staphylococcus haemolyticus ( one strain ) . - pubmed
Overall , patients with CKD had higher FRS risk score ( 25.9 % vs 20 % , p = 0.001 ) and more CVD events ( 22.3 % vs 11.9 % , p = 0.002 ) over a 10 - year period compared to patients without CKD . - pubmed
PURPOSE : To report a case of canine atypical chorioretinal coloboma where ophthalmoscopic , fluoroangiographic and optical coherence tomography characteristics are described . - pubmed
ANIMAL STUDIED : A 2 - year - old Golden Retriever dog in which routine ophthalmoscopic examination allowed diagnosis of a posterior coloboma on the left eye . - pubmed
CONCLUSIONS : Fluoroangiographic and optical coherence tomographic studies of an atypical chorioretinal coloboma in a dog are reported for the first time . - pubmed
Our study provided no direct support for high - concentration inspired oxygen in reducing the incidence of SSIs in patients undergoing all types of surgery . - pubmed
The methanolic extract revealed antioxidant activity and did not show hepatoxicity in porcine liver primary cells . - pubmed
SUBJECTS : Patients with histologically confirmed acute appendicitis . - pubmed
RESULTS : A total of 130 patients who had appendicectomy for acute appendicitis were included in the study . - pubmed
All the patients presented with right iliac fossa pain and tenderness . - pubmed
OCD typically arises in youth but delays in diagnosis impede optimal treatment and developmental studies of the disorder . - pubmed
KO mice exhibit compulsive self - grooming behavior analogous to behaviors found in people with OCRD . - pubmed
Striatal hyperactivity has been reported in these mice and in humans with OCD . - pubmed
At the age range studied , only 1 of 8 KO mice had skin lesions indicative of severe compulsive grooming . - pubmed
Anticancer activity of an ultrasonic nanoemulsion formulation of Nigella sativa L. essential oil on human breast cancer cells . - pubmed
PURPOSE OF REVIEW : Legionella pneumophila is a facultative intracellular pathogen and an important cause of community - acquired and nosocomial pneumonia . - pubmed
OBJECTIVE : To evaluate and describe the sleep quality in seven subscales among the patients with mild traumatic brain injury ( TBI ) and compare it with normal patterns . - pubmed
RESULTS : Overall we included 60 patients with mild TBI with mean age of 36.2 + -13.4 years . - pubmed
All the patients had sleep disturbance . - pubmed
CONCLUSION : Patients with mild TBI have poor sleep quality which should be considered as one of the main factors in interventions after the injury and it might lead to better quality of life . - pubmed
We report a rare case of bilateral pneumothoraces resulting from tracheostomy in an advanced laryngeal cancer patient . - pubmed
A 59 - year - old man was referred to our clinic for evaluation and treatment of laryngeal tumor . - pubmed
Primary optic nerve sheath meningiomas ( PONSM ) are rare in children . - pubmed
A 5 - year - old girl presented with visual impairment and proptosis . - pubmed
Prospective randomized evaluation of the watchman left atrial appendage closure device in patients with atrial fibrillation versus long - term warfarin therapy : The PREVAIL trial . - pubmed
OBJECTIVES : Assessing the safety and effectiveness of left atrial appendage ( LAA ) ( pouch found in the upper chambers of the heart ) occlusion , using the Watchman device compared to long term warfarin therapy ( drug that reduces clot formation ) , in preventing the risk of stroke in patients with atrial fibrillation ( most common type of irregular heart beat ) . - pubmed
METHOD : Patients with atrial fibrillation and at high risk of stroke were randomly allocated a group after they were deemed eligible . - pubmed
CONCLUSION : LAA occlusion is a reasonable alternative to chronic warfarin therapy in stroke prevention for patients with atrial fibrillation . - pubmed
Sleep problems in children with dyslexia : understanding the role of sleep in neurocognitive development through the lens of developmental disorders . - pubmed
Eculizumab is a safe and effective treatment in pediatric patients with atypical hemolytic uremic syndrome . - pubmed
The current role of MEG for presurgical evaluation with regard to noninvasive localization in MRI normal patients , guiding of invasive electrode implantation and correlation to postoperative outcome after epilepsy surgery is stressed . - pubmed
SCOPE : Chicory inulin is a naturally occurring fructan that is conducive to glucose and lipid metabolism in patients with diabetes mellitus . - pubmed
This study aims to investigate the mechanism by which chicory inulin improves glucolipid metabolism in diabetic conditions . - pubmed
METHODS AND RESULTS : Rats were injected with streptozotocin and fed with high fat diet to induce diabetes , and then administrated with different doses of chicory inulin for 8 weeks . - pubmed
Randomized , controlled trials of restrictive RBC transfusion practices have shown equivalent patient outcomes compared with liberal transfusion practices , and meta - analyses have shown improved in - hospital mortality , reduced cardiac events , and reduced bacterial infections . - pubmed
The suitability of using a spore - forming ureolytic strain , Bacillus sphaericus , was evaluated for self - healing of concrete cracks . - pubmed
Presently described is lichenoid type cutaneous hyperpigmentation in a 46 - year - old female patient . - pubmed
Diabetic retinopathy ( DR ) affects over 93million people worldwide and is the number one cause of blindness among working age adults . - pubmed
METHOD : We reviewed preoperative and postoperative records of patients undergoing surgery for pituitary adenomas . - pubmed
RESULTS : Of 394 patients included for analysis , 29 cases ( 7.4 % ) fulfilled criteria for atypia . - pubmed
Patients with atypical tumours were significantly younger than those with typical adenomas . - pubmed
CONCLUSIONS : Patients with atypical non - functional pituitary adenomas are at risk for postoperative recurrence and disease progression , suggesting a need for adjuvant therapy . - pubmed
An important challenge to using fluorodeoxyglucose - positron emission tomography ( FDG - PET ) in clinical trials of brain tumor patients is to identify malignant regions whose metabolic activity shows significant changes between pretreatment and a posttreatment scans in the presence of high normal brain background metabolism . - pubmed
INTRODUCTION : although the outcome for patients with rheumatoid arthritis ( ra ) has improved in the past decades , adequate disease control can not be achieved in a substantial proportion of patients . - pubmed
Furthermore , the article summarizes and comments the drug 's efficacy and safety profile in RA patients . - pubmed
after MI in mice . - pubmed
C57BL/6J wild type mice in post - MI were inoculated with P.g . - pubmed
Plasma samples and twelve tissue samples from mice hearts after MI were obtained . - pubmed
METHODS : We retrospectively enrolled 14 patients with CADM - associated RPIPs and acute respiratory failure treated with PMX - DHP , corticosteroids , and immunosuppressive agents . - pubmed
The association with penile cancer , in particular non - invasive disease , and human papilloma virus ( HPV ) is well known . - pubmed
In vivo antimicrobial experiment with a rat subcutaneous model indicates the catechol - chitosan film at reduced state inhibits the bacterial growth and alleviates the infection of the incisions . - pubmed
Open wound healing tests with a mouse model indicate that the catechol - chitosan film suppresses the bacterial population at the wound site , induces less inflammation and promotes wound healing . - pubmed
Streptococcus Anginosus Group - associated Pyogenic Liver Abscess . - pubmed
General inclusion criteria included English - language randomised human trials reporting the use of ozone therapy in the topical treatment of chronic wounds . - pubmed
Leprosy is a chronic intracellular infection caused by the acid - fast bacillus , Mycobacterium leprae . - pubmed
Studying these important components of the adaptive immune system in leprosy patients is essential for better understanding of immune function , correlate(s ) the immunity and mechanism(s ) of its containment . - pubmed
METHODS : We created four groups according to sex and anxiety symptomatology : high - anxiety girls ( n = 24 ) and boys ( n = 25 ) , and low - anxiety girls ( n = 22 ) and boys ( n = 24 ) and recorded their cardiac function while they performed regular school activities . - pubmed
Medication adherence in patients with schizophrenia : a qualitative study of the patient process in motivational interviewing . - pubmed
Human brown adipose tissue : Underestimated target in metabolic disease ? - pubmed
Methods : Between March 2012 and December 2016 , 20 patients ( 21 lesions ) with benign bone tumors or tumor like conditions of proximal femurs were treated with DHS and intralesional curettage via Watson - Jones approach . - pubmed
The time of full weight - bearing was 2 days in 2 patients with giant cell tumor and 2 to 13 weeks with an average of 7.2 weeks in the other patients . - pubmed
Discontinuation of hormone therapy for elderly breast cancer patients after hypofractionated whole - breast radiotherapy . - pubmed
Bacterial spot caused by Xanthomonas perforans causes significant damage on tomato in Florida . - pubmed
Inductively coupled plasma mass spectrometric analysis of the fruit confirmed that Nano - MgO application did not lead to the accumulation of Mg , Cu , Ca , K , Mn , P , and S. This study is the first to demonstrate the potential of Nano - MgO against bacterial spot of tomato . - pubmed
[ Ningmitai Capsules relieve lower urinary tract symptoms in patients with benign prostatic hyperplasia : A short - term clinical observation ] . - pubmed
Objective : To observe the clinical effect and safety of the Chinese patent medicine Ningmitai Capsules ( NMT ) in relieving lower urinary tract symptoms ( LUTS ) in the patient with benign prostatic hyperplasia ( BPH ) . - pubmed
METHODS : We randomly assigned 40 BPH patients to an experimental and a control group of equal number to receive oral administration of NMT at 4 capsules tid and terazosin hydrochloride tablets at 2 mg qd , respectively , both for 14 days . - pubmed
CONCLUSIONS : NMT is safe and effective in relieving LUTS in BPH patients . - pubmed
RESULTS : Compared with the control group , the final body weight and body weight gain were significantly higher in HFD - fed rats , while the testicle / body weight ratios were lower ( P & lt ; 0.05 ) . - pubmed
Treatment with 4 - PBA attenuated HFD - induced histological damage , ameliorated the HFD - induced decrease in serum testosterone ( T ) , and reduced the rate of testicular cell apoptosis ( P & lt ; 0.05 ) in obese male rats . - pubmed
Liver mitochondrial respiratory plasticity and oxygen uptake evoked by cobalt chloride in rats with low and high resistance to extreme hypobaric hypoxia . - pubmed
We determined the cobalt chloride ( CoCl2 ) effects on liver mitochondrial plasticity and oxygen uptake in rats with low resistance ( LR ) and high resistance ( HR ) to extreme hypobaric hypoxia . - pubmed
We have unveiled several mechanisms leading to differentiated mitochondrial respiratory responses to hypobaric hypoxia in LR and HR rats . - pubmed
These results are particularly relevant once sprouted and fermented quinoa could be an alimentary source of interest , especially for disease risk prevention such as diabetes , obesity and dyslipidemias . - pubmed
This case reports a very rare case of IgG4 - RD presenting with a cutaneous lesion in a young female patient mimicking a lymphoproliferative disorder . - pubmed
OBJECTIVE : To evaluate the efficacy and clinical results of full endoscopic debridement and drainage ( FEDD ) for high - risk patients with spondylodiscitis . - pubmed
All patients had single - level infectious spondylodiscitis and were high - risk candidates for surgery . - pubmed
RESULTS : All 14 patients experienced immediate relief of back pain after FEDD , with no procedure - related complications . - pubmed
CONCLUSIONS : FEDD may be an effective alternative to extensive open surgery in patients with infectious spondylodiscitis , especially those who are high - risk candidates for surgery ( elderly patients with multiple comorbidities and patients in poor general condition ) . - pubmed
Nevertheless , the margin width remains controversial particularly in cirrhotic patients where optimal parenchymal preservation is necessary . - pubmed
Totally , 534 patients who received liver resection for HCC were included . - pubmed
The clinical profiles of the patients , tumor characteristics and patients ' survival were all collected . - pubmed
Most of the patients had hepatitis B ( 52.4 % ) and hepatitis C ( 24.0 % ) infection . - pubmed
BACKGROUND : : Tremor is present in almost half of multiple sclerosis ( MS ) patients . - pubmed
OBJECTIVES : : To clarify the structural and functional brain changes associated with the clinical phenotype of upper limb tremor in people with MS . - pubmed
METHODS : : Fifteen healthy controls ( 46.1 + - 15.4 years ) , 27 MS participants without tremor ( 46.7 + - 11.6 years ) and 42 with tremor ( 46.6 + - 11.5 years ) were included . - pubmed
RESULTS : : Tremor participants were found to have atrophy of the cerebellum and thalamus , and higher ipsilateral cerebellar lesion load compared to participants without tremor ( p & lt ; 0.020 ) . - pubmed
Introduction : The polyomaviruses , John Cunningham ( JC ) and BK , infect humans , with primary infection occurring in childhood . - pubmed
The absence of John Cunningham virus ( JCV ) , DNA was a strong predictor of CKD ( odds ratio [ OR ] 43.43 ; 95 % confidence interval [ CI ] 7.39 - 255.20 ; P & lt ; 0.001 ) . - pubmed
Longer Control of Nivolumab in Metastatic Renal Cell Carcinoma Patients with End - Stage Kidney Disease on Dialysis . - pubmed
However , despite widespread evidence of its utility , few reports have described the efficacy of nivolumab for mRCC patients on hemodialysis . - pubmed
Case Presentation : A 68 - year - old man with a 20 - year history of dialysis due to chronic glomerulotubular nephritis was referred to our department for bilateral renal tumors in 2015 . - pubmed
Conclusion : We herein report a patient with RCC on hemodialysis with long - term cancer control by nivolumab . - pubmed
[ Allogeneic stem cell transplantation in elderly patients with acute myeloid leukemia ] . - pubmed
Acute myeloid leukemia is a disease that mainly affects older populations , with a median age at diagnosis of 67 years , and outcomes for these patients are poor . - pubmed
We concluded that active cardiac assessment is a prudent step in patients presenting with sarcoidosis regardless of the organ of affectation at presentation or diagnosis . - pubmed
METHODS : Fifty patients with fan - shaped displacement of anterior teeth caused by periodontitis in PLA air force hospital from January 2013 to October 2018 were selected and randomly divided into the control group ( n=25 ) and the experimental group ( n=25 ) . - pubmed
The symptoms of periodontitis can be effectively improved , the teeth can be effectively corrected and facial profiles of the patients can be improved . - pubmed
Correlation study between the pharmacokinetics of seven main active ingredients of Mahuang decoction and its pharmacodynamics in asthmatic rats . - pubmed
To illustrate our arguments , we refer to the extent of regional cooperation for health in ASEAN and the EU for ( re)emerging infectious disease control and for tobacco control . - pubmed
While not all investigations observe a beneficial effect of these compounds , there are multiple studies that show a protective effect of each of these lifespan - extending compounds in animal models of neurodegenerative disease . - pubmed
BACKGROUND : Modern chemotherapeutics have led to improved systemic disease control for patients with locally advanced pancreatic cancer ( LAPC ) . - pubmed
Hypogonadism and bone health in men with HIV . - pubmed
The advent of new classes of antiretroviral drugs has improved the survival of people with HIV , and several ageing - related conditions , including hypogonadism and osteoporosis , have emerged . - pubmed
BACKGROUND : The aim of this study was to evaluate the cardio - metabolic risk in schizophrenia patients treated by atypical antipsychotic drugs compared with that in those treated without atypical antipsychotic drugs using a nationwide insurance claims database and medical examination database in Japan . - pubmed
METHODS : Eligible patients were defined as those meeting the following two criteria : ( i ) A diagnosis of schizophrenia ( ICD-10 code : F20 ) was made between 1 January 2005 and 31 December 2017 , with data available for at least 6 months before the diagnosis was made ( index month ) , and ( ii ) health check - up data were available within + -3 months of the index month . - pubmed
Patients receiving atypical antipsychotic drugs exhibited a greater change in the Suita score and a risk of coronary heart disease based on the Suita score of 0.530 and 0.098 % , respectively , than patients not receiving atypical antipsychotic drugs , but there was no significant difference ( p = 0.412 and 0.610 ) . - pubmed
Proximal intestinal obstruction syndrome ( PIOS ) in a patient with cystic fibrosis : A case report . - pubmed
Presentation of case : We report a case of a 45 years old patient with cystic fibrosis , who presented bowel obstruction secondary to accumulation of fecal material , combined with mucous secretions , in the mid - jejunum . - pubmed
Discussion : We present a case of a patient with cystic fibrosis presenting with bowel obstruction due to a proximal intestinal obstruction syndrome , which can be diagnosed with the DIOS definition , with the only distinction of a more proximal location in the gastrointestinal tract , such as the stomach , the duodenum , or the jejunum . - pubmed
The effects of miR-30a-3p overexpression on the proliferation and apoptosis as well as oxidative stress injury were evaluated in rats RA - FLS . - pubmed
Further investigation indicated that miR-30a-3p agomir exerted anti - arthritic effects on adjuvant - induced arthritis ( AA ) in rats . - pubmed
[ Osteoprotective effect of bread enriched with protein , dietary fiber , calcium , iron and iodine in hypoestrogen - induced osteoporosis among rats ] . - pubmed
The aim was to study the effect of bread enriched with protein , dietary fiber , calcium , iron and iodine on the state of the bone tissue of rats in a model of postmenopausal osteoporosis . - pubmed
The experiment was performed on sexually mature female Wistar rats divided into groups : K - control ( sham - operated rats , not ovariectomized ) ; O30 - osteoporosis model ( animals were sacrificed 30 days after ovariectomy ) ; groups O120 and O120 + - a model of osteoporosis ( rats were sacrificed 120 days after ovariectomy ) . - pubmed
For rats of the O120 + group , from the 40th to the 120th day , enriched bread was included in the diet in an amount of 6 g per 100 g of body weight per day . - pubmed
The micro - architectural structure of the femur in the O120 + group of rats was close to that of the O30 sample , which serves as a model of the early stage of osteoporosis ( SMI 1.42 + -0.07 ; TbPf 5.55 + -0.28 1 / mm ) . - pubmed
Bread enriched with protein , fiber , calcium , iron and iodine , effectively weakens osteoporosis induced by ovariectomy in rats . - pubmed
METHODS : Our internal registry was used to identify all patients who received surgical treatment of an acl tear during childhood and adolescence by transepiphyseal acl reconstruction more than 15 years previously . - pubmed
None of the included patients showed a growth disorder during the course of the study . - pubmed
In 92 % of patients , an intact acl reconstruction was found without evidence of cartilage or meniscus damage . - pubmed
These were compared with adult normal mouse lung and lungs of the animals treated with 4 - nitroquinoline 1 - oxide at a monthly interval until cancer developed . - pubmed
Catecholamine levels in discrete brain nuclei of seven month old genetically obese rats . - pubmed
Muco - cutaneous leishmaniasis : intradermal test with a promastigote suspension and a crude extract from Leishmania braziliensis . - pubmed
We tried this catheter for 11 various urological patients who needed a long - term indwelling of a balloon catheter for lower urinary tract obstruction and neurogenic bladder . - pubmed
All patients were already indwelled silicon balloon catheter for 3 to 6 months and suffered with complicated urinary tract infection . - pubmed
Two patients ( 22.2 % ) showed good results by the urinary tract infection ( UTI ) criteria and 5 patients ( 55.4 % ) showed good effects by doctor 's judgment . - pubmed
A randomized controlled trial was performed to study the efficiency of adjuvant chemotherapy with early intravesical instillation of Adriamycin and long - term oral administration of 5 - fluorouracil in 275 patients with superficial bladder cancer . - pubmed
To clarify the existence of the vertical component during a caloric nystagmus and the existence of a second phase of the nystagmus , 194 induced incidents of a caloric nystagmus in 29 normal subjects have been analyzed . - pubmed
An immunocorrective effect of current methods of detoxication in experimental acute destructive pancreatitis was studied on 40 mongrel male dogs with body mass 13 - 15 kg . - pubmed
Following 6 h of left middle cerebral artery occlusion , rat brains were frozen in situ . - pubmed
To address these issues , we reviewed the clinicopathologic and immunohistochemical features of 22 cases ( 11 men and 11 women ; mean age , 56 years ) of laryngeal amyloidosis . - pubmed
Six patients had concomitant tracheal amyloidosis . - pubmed
Ten patients underwent repeated operations for persistent or recurrent respiratory tract disease . - pubmed
One patient died of progressive tracheobronchial amyloidosis , but systemic amyloidosis did not develop in any of the patients . - pubmed
[ The immunological rehabilitation of patients with chronic nonspecific lung diseases at sanatoria and health resorts ] . - pubmed
Histoplasmosis relapse in patients with AIDS : detection using Histoplasma capsulatum variety capsulatum antigen levels . - pubmed
OBJECTIVE : To assess the accuracy of Histoplasma capsulatum variety capsulatum polysaccharide antigen testing for the identification of histoplasmosis relapse in patients with the acquired immunodeficiency syndrome ( AIDS ) . - pubmed
PATIENTS : Twenty episodes of histoplasmosis relapse were evaluated in 17 patients with AIDS from November 1987 to August 1990 . - pubmed
Controls included 30 patients with AIDS and histoplasmosis who did not have a relapse during maintenance therapy and who were initially tested during the same week as the patients with relapse . - pubmed
A second control group included seven patients with AIDS and histoplasmosis who were evaluated for relapse on 23 occasions ; relapse , however , was excluded on each occasion . - pubmed
MAIN RESULTS : For the 20 episodes of relapse ( 17 patients ) , H.c . - pubmed
Forty patients underwent pancreaticoduodenectomy for malignant disease in a 25 - year review of 6 Portland - area hospitals . - pubmed
One hundred and eighteen patients with acute unilateral sensorineural hearing loss were examined . - pubmed
Serological tests were performed including influenza- , parainfluenza- , adenovirus- , RS - virus , enterovirus- , morbilli- , varicella- and cytomegalie - virus - KBR , also the serological tests for toxoplasmosis , rheuma , lues , mycosis , and Borrelia . - pubmed
The cardiovascular responses of rats of different ages , ranging from 4 - 15 weeks ( body weight 115 - 490 g ) , to acute left coronary artery ligation under pentobarbitone anaesthesia were studied . - pubmed
In older animals , the responses included the occurrence of ventricular tachycardia and/or fibrillation , decrease in blood pressure , and a slight increase in heart rate . - pubmed
On the contrary , younger rats exhibited atrioventricular block followed by ventricular arrest , and decreases in both blood pressure and heart rate . - pubmed
The findings demonstrate the existence of age - related cardiovascular responses to acute myocardial ischaemia in rats , and suggest that 10 - 15 - week - old male Sprague - Dawley rats are suitable experimental animals for producing early ventricular arrhythmias by acute coronary artery ligation . - pubmed
88 % of the patients showed a considerable improvement : 69 % were free from arrhythmias and 33 % exhibited a significant reduction . - pubmed
Influence of hypercholesterolemia and cholesterol accumulation on rabbit carrageenan granuloma macrophage activation . - pubmed
These experiments were designed to determine whether hypercholesterolemia and the accumulation of cholesterol or cholesteryl esters in rabbit carrageenan granuloma macrophages might influence selected markers of macrophage activation . - pubmed
Granulomas induced by subcutaneous injection of carrageenan into rabbits were harvested after 4 , 14 , and 28 days . - pubmed
Increasing exposure of the elderly to pharmacologic agents that reduce CH2O is primarily responsible for the impression that aged patients are at increased risk for hyponatremia . - pubmed
A commercial enzyme - linked immunosorbent assay ( ELISA ) to detect serological response to vaccination and virulent challenge with type 1 ( X-73 ) Pasteurella multocida was used to determine the best vaccination protocol for broiler breeders against fowl cholera . - pubmed
Sixty - five patients with histologically proven chronic active hepatitis of unknown cause but associated with the antiliver / kidney microsome antibody type 1 , confirmed by immunofluorescence and immunoprecipitation , were selected as forming a special entity . - pubmed
The clinical course was usually severe : six patients in the acute stage presented with fulminant hepatitis , and all , except two , other patients progressed to cirrhosis . - pubmed
The incidence of side effects is generally low , but in the elderly and in patients with renal or hepatic failure , both of these drugs can produce confusional states . - pubmed
Proteins , animal fats , disugars and products of animal origin , refined products and daily energy content of rations were shown to be directly related to CHD morbidity ( 0.61 - 0.94 ) , arteriosclerosis ( 0.70 - 0.96 ) , myocardial infarction and cardiosclerosis ( 0.67 - 0.96 ) mortality , their association with hypertension being reverse ( -0.66 - 0.80 ) . - pubmed
Vegetable fats , starch , cellulose , hemicellulose , pectin , buns and rolls , vegetables and fruit showed reverse correlation with CHD morbidity ( -0.53 - 0.88 ) as well as with arteriosclerosis ( -0.57 - 0.95 ) , myocardial infarction and cardiosclerosis ( -0.61 - 0.96 ) mortality . - pubmed
Anaphylactic release of histamine from guinea pig skin in vitro . - pubmed
Pulmonary nodule caused by a living Brugia malayi - like filaria in an artery . - pubmed
[ The effect of DDT poisoning on the quantity and swelling of mitochondria of wing musculature isolated from susceptible and resistant flies Musca domestica L ] . - pubmed
As a compensatory mechanism in approximately one third of patients with palatopharyngeal insufficiency , the superior constrictor muscle may be active in the form of Passavant 's ridge . - pubmed
Seven children with Crohn ' s disease and linear growth retardation were studied in order to determine the best method of treating this psychologically debilitating complication . - pubmed
[ Therapeutic criteria for the use of nifedipine in patients with chronic aortic insufficiency ] . - pubmed
Neurotransmitters in the treatment of patients with severe head injuries . - pubmed
Results of treatment with L - dopa and/or physostigmine of patients with severe head injuries were examined and discussed . - pubmed
This treatment given to patients still unconscious a long period after trauma resulted in clinical improvement in 29 of the 45 trials ( 64 % ) . - pubmed
The metabolism of mevalonate was studied in 6 dog kidneys and in 5 human tumour - involved kidneys during 6 days of hypothermic perfusion . - pubmed
A patient with severe , penetrating brain injury is presented . - pubmed
The patient was in psychiatric treatment for four years , starting two months after the injury ; psychological tests were administered four times . - pubmed
A strain of Streptomyces , isolated from a soild sample and identified as Streptomyces unzenensis sp . - pubmed
Local cerebral blood flow after middle cerebral artery occlusion in rabbits following transposition of omentum to the brain . - pubmed
Transposition of pedicled omental grafts to the brain has been shown to minimize the effects of cerebral infarction in dogs and monkeys . - pubmed
Strain- and sex - linked effects of dietary polyunsaturated fatty acids on tumor growth and immune functions in mice . - pubmed
In the present paper , we studied the influence of different levels of dietary polyunsaturated fatty acids ( PUFA ) on the immune system and tumor growth in young mice . - pubmed
Female BALB / c mice fed a PUFA - rich diet display an enhanced body growth , proliferative response to mitogens in vitro , and rate of growth of a spontaneous transplantable adenocarcinoma as compared to PUFA - poor diet - fed females . - pubmed
Moreover , in female DBA/2 mice with the same haplotype ( H-2d ) of the major histocompatibility complex as that of BALB / c mice , low dietary PUFA determines a reduced tumor growth only , but it does not affect body growth and proliferative response to mitogens in vitro . - pubmed
Cytotoxicity and DNA cross - linking activity of 4 - sulfidocyclophosphamides in mouse leukemia cells in vitro . - pubmed
Binary combinations of pure chemicals and complex mixtures were evaluated for their ability to produce additive mutagenicity responses in the spiral and standard Salmonella mutagenicity assays . - pubmed
The purpose of the work was an assessment of the usefulness of transcutaneous measurement of O2 pressure in the foot ( in recumbent position , recumbent with venostasis , elevated and erect position ) for the detection of microcirculation disturbances in patients with diabetes mellitus . - pubmed
The studies included 43 patients with type I and II diabetes without haemodynamically significant stenoses of the axial arteries of the lower limbs , and a control group of 14 . - pubmed
It was found that already in the period preceding the development of obliterative lesions in the arteries , microcirculation disturbances in the lower limbs became manifest causing statistically significant decrease of tcPO2 in patients with type I and II diabetes mellitus . - pubmed
We describe a patient with systemic mastocytosis associated with chronic myelomonocytic leukemia accompanied by ascites , pleural effusion , and development of skin lesions along a surgical scar . - pubmed
To evaluate the role of platelets in patients with sepsis and MOF , we examined changes in surface glycoproteins on circulating platelets of 14 patients with suspected sepsis and MOF . - pubmed
Since mental practice in healthy people leads to central nervous activation processes as well as to an improvement of motor skills , we investigated the effects of mental practice alone on central nervous activity by means of EEG in stroke patients . - pubmed
Twelve left - sided hemiplegic patients who underwent a specific poststroke rehabilitation treatment were requested to perform a simple arm movement sequence . - pubmed
In tall animals dependent tissues are stiffer to prevent oedema formation in the upright posture , but whether the same adaptation is operating in man is not known . - pubmed
New benzo [ a ] naphthacenequinone metabolites , designated bequinostatins A and B , have been isolated from the culture broth of the benastatin - producing strain Streptomyces sp . - pubmed
Cerebellar ataxia , meningitis and cerebral infarction were found in young children under 9 years , and other disorders were seen also in older children and adults . - pubmed
In our 4 cases of herpes zoster meningitis , marked intrathecal VZV - specific antibody production was found and they showed high antibody index . - pubmed
Morning variations of plasma homovanillic acid in untreated schizophrenic patients . - pubmed
Plasma concentrations of homovanillic acid were determined in samples obtained at 8.30 a.m. and 12.30 p.m. from 29 untreated schizophrenic patients , 14 males and 15 females . - pubmed
Genotoxicity studies of quercetin and shikimate in vivo in the bone marrow of mice and gastric mucosal cells of rats . - pubmed
Bracken fern ( Pteridium aquilinum ) causes acute and chronic toxicity in animals and is associated with a high incidence of stomach and esophageal tumors in humans in countries where it is consumed as food , yet the toxic constituent(s ) has not been unequivocally identified . - pubmed
The carcinogenicity of the plant has at one time or another been attributed to quercetin , shikimate or ptaquiloside . - pubmed
Studies to determine whether or not the genotoxicity of quercetin , shikimate ( and its metabolite cyclohexane - carboxylate ) could be enhanced in combined application were conducted in vivo using the micronucleus test in mice and the unscheduled DNA synthesis in rat gastric mucosal cells . - pubmed
Effects of nordihydroguaiaretic acid on murine antibody - dependent cellular cytotoxicity . - pubmed
Antibody - dependent cellular cytotoxicity mediated by murine spleen cells was significantly inhibited by concentrations of nordihydroguaiaretic acid from 10(-5 ) to 10(-4 ) M ( 1C50 = 2 x 10(-5 ) M ) . - pubmed
These results suggest that arachidonic acid metabolites other than leukotriene B4 are released by different populations of spleen cells to positively regulate important events in the postbinding phase of murine antibody - dependent cellular cytotoxicity . - pubmed
We report three patients who were operated on because of an intraabdominal schwannoma between February 1991 and October 1994 in our department . - pubmed
Eleven dogs were exercised on a treadmill at 3 km / hr for 75 minutes 5 days a week for 527 weeks while carrying jackets weighing 130 % of their body weight . - pubmed
These results show that a lifetime of regular weightbearing exercise in dogs with normal joints did not cause alterations in the structure and mechanical properties of articular cartilage that might lead to joint degeneration . - pubmed
An analysis of 676 consecutive prostatectomies revealed that 4.3 % of the men had tumor touching the inked bladder neck margin . - pubmed
A 52 - year - old man with a history of portal hypertension was intubated emergently for airway protection because of respiratory insufficiency due to sepsis . - pubmed
At the conclusion of the procedure , the patient sustained large volume hematemesis due to esophageal variceal rupture . - pubmed
This case report provides strong evidence in support of administering fentanyl , or a suitable alternative adjunctive medication , before intubation of patients with documented portal hypertension and a history of esophageal variceal hemorrhage . - pubmed
PURPOSE OF STUDY : To establish a diagnosis and therapeutic management in patients with extramedullar plasmocytomas . - pubmed
One patient with a nasal cavity tumor location and a review of literature are reported . - pubmed
Phase II trial of weekly intravenous gemcitabine with continuous infusion fluorouracil in patients with metastatic renal cell cancer . - pubmed
Patients had a Cancer and Leukemia Group B performance status of 0 or 1 , with a median time since diagnosis of metastatic disease of 10 months ( range , 0 to 129 months ) . - pubmed
CONCLUSION : Weekly gemcitabine with continuous infusion 5 - FU is an active combination in patients with metastatic RCC . - pubmed
Significant abnormality ( stenosis & gt ; 70 % or occlusion ) was found in 20 % of the patients . - pubmed
Class Ic drugs are not advisable for patients with structural cardiac abnormalities secondary to a high risk of proarrhythmia . - pubmed
The risk of proarrhythmia is increased in patients with abnormal cardiac substrate , with electrolyte abnormalities , and during drug initiation . - pubmed
We estimated U and sh ( the heterozygous effect of mutations ) for two diploid yeast strains differing only in the DNA mismatch - repair deficiency used to elevate the mutation rate in one ( mutator ) strain . - pubmed
In order to investigate the presence of membrane protein defects we investigated the erythrocyte membrane protein composition and phosphorylation in 22 children with leukemia at diagnosis and during the remission phase . - pubmed
Sixteen children had acute lymphoblastic leukemia ( ALL ) , three had chronic myeloid leukemia ( CML ) and three had acute myeloid leukemia ( AML ) . - pubmed
The STI and HIV epidemics are interdependent . - pubmed
Similar behaviours , such as frequent unprotected intercourse with different partners , place people at high risk of both infections , and there is clear evidence that conventional STIs increase the likelihood of HIV transmission . - pubmed
Several studies have demonstrated a strong association between both ulcerative and non - ulcerative STIs , and HIV infection ( Cameron 1989 , Laga 1993 ) and there is biological evidence that the presence of an STI increases shedding of HIV and that STI treatment reduces HIV shedding ( Cohen 1997 , Robinson 1997 ) . - pubmed
Therefore , STI control may have the potential to contribute substantially to HIV prevention . - pubmed
In Mwanza , the incidence of HIV infection in the intervention groups ( strengthened syndromic management of STIs in primary care clinics ) was 1.2 % compared with 1.9 % in the control groups ( OR=0.58 , 95 % CI 0.42 - 0.70 ) , corresponding to a 38 % reduction ( 95%CI 15 % to 55 % ) in HIV incidence in the intervention group . - pubmed
REVIEWERS ' CONCLUSIONS : There is limited evidence from randomised controlled trials for STI control as an effective HIV prevention strategy . - pubmed
Improved STI treatment services have been shown to reduce HIV incidence in an environment characterised by an emerging HIV epidemic ( low and slowly rising prevalence ) , where STI treatment services are poor and where STIs are highly prevalent . - pubmed
Such trials should aim to measure a range of factors that include health seeking behaviour and quality of treatment as well as HIV , STI and other biological endpoints . - pubmed
The results show that although FNAC is relatively inexpensive and minimally invasive , it can not be relied upon to provide an accurate tissue diagnosis , may fail to identify malignancy and does not prevent patients undergoing surgery for non - neoplastic conditions . - pubmed
Increased urine catecholamine levels were observed only in the patient with neuroblastoma . - pubmed
iron infusions represent a practical alternative to oral iron and can be safely administered to PD patients in an outpatient setting . - pubmed
[ Epstein - Barr virus - encoded small RNA and oncogenesis ] . - pubmed
Patients with a greater drop in blood pressure experienced no improvement in exercise - induced ischemia . - pubmed
METHODS - From May 1998 to July 2000 , 33 patients with clinical and laboratory diagnosis of persistent ductus arteriosus underwent attempts at percutaneous implantation of the Amplatzer prosthesis . - pubmed
All patients were followed up with periodical clinical and echocardiographic evaluations to assess the presence and degree of residual shunt and possible complications , such as pseudocoarctation of the aorta and left pulmonary artery stenosis . - pubmed
The purpose of the present study was to obtain insight into the natural development of adaptive intimal thickening and atherosclerosis in the arterial tree of human species . - pubmed
Within elderly humans , features of advanced atherosclerotic disease , a lipid - rich core and macrophages , can be observed in the intimal layer of artery types that are recognised for their relation with clinical syndroms as well as artery types that remain clinically silent . - pubmed
Assuming that the mechanisms of action of apomorphine are similar in humans and animal models , its use for the treatment of erectile dysfunction ( ED ) validates the emerging idea that erectile response could be enhanced by acting directly within the central nervous system ( CNS ) . - pubmed
Transformed and tumor - derived human cells exhibit preferential sensitivity to the thiol antioxidants , N - acetyl cysteine and penicillamine . - pubmed
To test whether sensitivity to antioxidants is a general property of immortalized human cells , including fully transformed cells , 12 tumor - derived cell lines were treated with PEN , the more potent of the two antioxidants . - pubmed
High - dose samarium-153 ethylene diamine tetramethylene phosphonate : low toxicity of skeletal irradiation in patients with osteosarcoma and bone metastases . - pubmed
Theiler ' s virus infection of the central nervous system ( CNS ) induces an immune - mediated demyelinating disease in susceptible mouse strains , such as SJL / J , and serves as a relevant infectious model for human multiple sclerosis . - pubmed
Therefore , the susceptibility of SJL / J mice is not due to the lack of an early functional Theiler 's murine encephalomyelitis virus - specific CTL response . - pubmed
OBJECTIVE : We sought to determine the results of surgical treatment of patients with tetralogy of Fallot and pulmonary atresia with or without major aortopulmonary collateral arteries , to clarify variables affecting early and late mortality , and to expose late , nonfatal events affecting surgical patients . - pubmed
Twenty - two ( 6.6 % ) patients underwent reopening of the ventricular septal defect for high right ventricular pressure . - pubmed
CONCLUSIONS : Surgical repair of patients with simple or complex forms of tetralogy of Fallot with pulmonary atresia can be achieved with low early mortality . - pubmed
There was osteogenic relapse involving the bone of the orbit , 20 days after macroscopically complete excision of the primary tumour when the patient was 12 weeks old . - pubmed
Ectopic expression of cell cycle markers in models of induced programmed cell death in dopamine neurons of the rat substantia nigra pars compacta . - pubmed
BACKGROUND : Cancer gene therapy is now being developing to provide new strategies for the treatment of human tumors . - pubmed
Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids , hecogenin and tigogenin , on human 1547 osteosarcoma cells . - pubmed
We compared the biological activity of diosgenin with hecogenin and tigogenin , plant steroids structurally close to diosgenin , on proliferation rate , cell cycle distribution and apoptosis in human 1547 osteosarcoma cells . - pubmed
To evaluate the vector competence of Culex tarsalis Coquillett for West Nile virus ( WN ) , females reared from larvae collected in Huntington Beach , Orange County , CA , were fed on 2 - 3 - day - old chickens previously inoculated with a New York strain ( Crow 397 - 99 ) of WN . - pubmed
Sixty - four patients with mild to moderate AD were retrospectively selected by two European centres . - pubmed
We reviewed autopsy material from patients who died of diffuse alveolar damage in the clinical setting of pulmonary fibrosis , both idiopathic and with background fibrosing alveolitis with connective tissue disorders ( FA - CTDs ) , and compared them with cases of acute interstitial pneumonia . - pubmed
Capsaicin - induced hyperalgesia and mu - opioid - induced antihyperalgesia in male and female Fischer 344 rats . - pubmed
The influence of sex in determining responses to opioid analgesics has been well established in rodents and monkeys in assays of short - lasting , phasic pain . - pubmed
The purpose of this investigation was to use a capsaicin model of tonic pain to evaluate sex differences in hyperalgesia and mu - opioid - induced antihyperalgesia in Fischer 344 ( F344 ) rats . - pubmed
Capsaicin injected into the tail produced a dose - dependent thermal hyperalgesia in males and females , with the dose required to produce a comparable level of hyperalgesia being 3.0 - fold higher in males than in females . - pubmed
These data contrast with the finding that mu - opioids are more potent in male rodents in assays of phasic pain , thus suggesting that distinct mechanisms underlie male and female sensitivity to opioid antinociception in phasic and tonic pain models . - pubmed
These findings emphasize the need to test male and female rodents in tonic pain assays that may have greater relevance for human pain conditions . - pubmed
Tobacco smoking , motor exhaust fumes , and general air pollution in relation to lung cancer incidence . - pubmed
[ On the carcinogenic substances in the external surroundings of man and the prevention of cancer ] . - pubmed
Forty - six patients with AD , 7 patients with FLD and 34 normal controls ( CTR ) were included in the study . - pubmed
Peripheral blood mononuclear cell ( PBMC ) cytotoxicity against S. - pubmed
In the present study , we injected rats with multiple doses of dimethylnitrosamine for 4 weeks and used rats with severe LC to determine whether colchicine treatment improved liver functions and resolved cirrhotic nodules . - pubmed
Haemangiopericytoma ( HPT ) is a rare neoplasm that can occur in any part of the human body . - pubmed
In this report , we describe the case of a patient with sudden severe upper abdominal pain caused by primary HPT in the greater omentum . - pubmed
, is one of the most important fungal diseases that has been shown to cause significant yield losses on chickpeas in Kermanshah province , Iran . - pubmed
Disease resistance of four chickpea cultivars , Hashem , Jam , ILC-482 and Bivanij , were evaluated against isolates from each of three groups separately and in combination in the greenhouse and field conditions ( with 4 replications ) . - pubmed
BACKGROUND : Mesorectal margin tumour involvement is a predictor of local recurrence in rectal carcinoma and an indication for postoperative radiotherapy in suitable patients . - pubmed
Despite advances in coronary angioplasty for acute myocardial infarction ( MI ) , the mortality rate for patients presenting with cardiogenic shock remains high . - pubmed
This case review describes the management of a patient with a non - ST segment elevation MI complicated by cardiogenic shock . - pubmed
We examined the relationship between left atrial volumetric remodeling and objective measures of exercise capacity in patients with nonobstructive hypertrophic cardiomyopathy ( HCM ) . - pubmed
This simple noninvasive measure of LA size may provide a long - term indication of the effects of chronically elevated filling pressures in patients with HCM and further studies testing its prognostic value are necessary . - pubmed
The aim of the present study was to determine the mechanism of angiotensin - converting enzyme inhibitor ( ACEI ) on the progression of rat hepatic fibrosis . - pubmed
Previously , we generated mice carrying the R192Q mutation , associated with human familial hemiplegic migraine type-1 , and showed first evidence of enhanced presynaptic Ca ( 2 + ) influx [ Neuron 41 ( 2004 ) 701 ] . - pubmed
Here , we characterize transmitter release in detail at mouse R192Q NMJs , including possible gene - dosage dependency , progression of changes with age , and associated morphological damage and muscle weakness . - pubmed
Spinal endoscopy has been widely used to treat patients with cervical , thoracic , and lumbosacral disorders safely and effectively . - pubmed
In order to obtain a comprehensive picture of the molecular events regulating cutaneous photodamage of intact human epidermis , suction blister roofs obtained after a single dose of in vivo ultraviolet ( UV)B exposure were used for microarray profiling . - pubmed
OBJECTIVE : To evaluate the clinicopathologic features and prognosis of patients with orbital lymphomas . - pubmed
METHODS : Clinical and pathologic data of 35 patients with biopsy - proven orbital lymphoma diagnosed at a tertiary care hospital from 1992 to 2001 were reviewed . - pubmed
Survival of patients was compared according to age , gender , disease site , extent of disease , tumor grade , and treatment modality by using log rank test . - pubmed
Twenty - three patients ( 66 % ) were diagnosed with low - grade lymphoma , and 12 patients ( 34 % ) were found to have high - grade lymphoma . - pubmed
Among low - grade lymphomas , marginal zone lymphoma ( n=6 ) , follicle center cell lymphoma ( n= 6 ) , and small lymphocytic lymphoma ( n=5 ) were common entities , whereas diffuse large cell B - cell lymphoma ( n=5 ) was the most common entity in patients with high - grade lymphoma . - pubmed
Overall , 13 ( 37 % ) patients died , 6 with high - grade and 7 with low - grade lymphoma . - pubmed
The seasonality of sarcoidosis in symptomatic , recently diagnosed patients with Lofgren ' s syndrome was evaluated to help better understand the possible causative factor(s ) in the pathogenesis of sarcoidosis . - pubmed
METHODS : Four hundred and ninety - two consecutive patients with sarcoidosis were investigated . - pubmed
PURPOSE : Immediate spica cast application is the standard of care for young children with isolated femur fractures . - pubmed
CONCLUSIONS : The single - leg spica can safely , effectively manage low - energy femur fractures in young children . - pubmed
A seizure - paralysis repertoire characteristic of Drosophila " bang - sensitive " mutants can be evoked electroconvulsively in tethered flies , in which behavioral episodes are associated with synchronized spike discharges in different body parts . - pubmed
BACKGROUND : Data on the subtypes of HIV in a population help in predicting the potential foci of epidemic , tracking the routes of infection and following the patterns of the virus ' genetic divergence . - pubmed
Globally , the most prevalent HIV infection is the HIV-1 subtype C. In Asia , predominant subtypes of HIV-1 are B , C , and CRF-01AE . - pubmed
As the prevalence of HIV in Pakistan continues to rise , more work needs to be done to track the infection , and to analyze the strains of HIV spreading through the country . - pubmed
Correlation between the appearance of neuropeptides in the rat trigeminal ganglion and reinnervation of the healing root socket after tooth extraction . - pubmed
Most human infections with the protozoan parasite Toxoplasma gondii are asymptomatic , but severe symptoms can occur in immunocompromised patients , in developing foetuses , and in ocular infections in immunocompetent individuals . - pubmed
Such a scenario can be found following infection of adult mice with an immunosuppressive variant of lymphocytic choriomeningitis virus ( LCMV ) referred to as clone 13 . - pubmed
Interestingly , the combination of ZD4054 and paclitaxel produced additive antitumor effects , with 40 % of mice remaining tumor - free , supporting a rationale for the clinical use of ZD4054 as monotherapy or in combination with cytotoxic drugs . - pubmed
Peritoneal samples from the omentum of adult sheep were isolated immediately after the deaths of the animals and were transferred to the laboratory in cooled Krebs - Ringer bicarbonate solution ( 4 degrees C , pH 7.5 ) bubbled with 95 % O2/5 % CO2 . - pubmed
Those findings , combined with the results of the present study , clearly indicate that intraperitoneal administration of digitalis glycosides may have some beneficial effect in PD patients ; however the specific clinical implications need further investigation . - pubmed
Objectives To establish the lifetime prevalence of clinically manifest orofacial herpes and its relationship with herpes simplex virus ( HSV ) serotype in the French general population . - pubmed
PATIENTS / METHODS : Subjects ( N = 2796 ) were serotyped for HSV1 and HSV2 and provided data on herpetic symptoms by questionnaire . - pubmed
Retinoic acid downregulates microRNAs to induce abnormal development of spinal cord in spina bifida rat model . - pubmed
To this end , we have studied the mechanism of microRNAs involved in the morphogenesis of the spinal cord in all - trans - retinoic acid ( RA)-treated spina bifida rat fetus . - pubmed
A 68 - year - old man had malaise , weight loss , and enlarged right cervical lymph nodes . - pubmed
Because of their effects on sodium , vasopressin antagonists need to be carefully monitored to ensure that serum sodium levels do not increase too quickly and put the patient at risk for overcorrection or osmotic demyelination syndrome . - pubmed
In addition , patients need to be monitored for signs of dehydration secondary to increased urine excretion . - pubmed
To date , studies have not consistently shown improvements in patient symptoms or weight reduction . - pubmed
CONCLUSION : Based on data from available clinical trials , vasopressin antagonists may offer a new treatment option for patients with congestive heart failure . - pubmed
Azacitidine has been shown to have survival benefits in patients with high - risk myelodysplastic syndrome ( MDS ) , and has activity in the treatment of acute myelogenous leukemia ( AML ) . - pubmed
In a formulation feasibility pilot study , four subjects with solid malignant tumors , AML or MDS received single oral doses of 60 or 80 mg azacitidine . - pubmed
Effects of glycine on motor performance in rats after traumatic spinal cord injury . - pubmed
In order to assess the effects of glycine administration on motor performance after SCI , we used fifteen male Wistar rats distributed into three groups : sham ( n = 3 ) , spinal - cord injury ( n = 6 , ) and spinal cord injury + glycine ( n = 6 ) . - pubmed
Results showed that for all animals with spinal - cord injury , scores in the beam - walking increased , which is an indication of increased motor deficit . - pubmed
The aim of the study was to examine the association between estimated glomerular filtration rate ( GFR ) , presence of CAD , and prognosis in patients with reversible perfusion defects at gated single - photon emission computed tomography ( g - SPECT ) . - pubmed
RESULTS : GFR was lower in patients with CAD and after adjusting for several clinical characteristics through multivariate logistic regression analysis , reduced ( & lt;60 mL / min/1.73 m(2 ) ) GFR remained a significant predictor of CAD ( HR 1.80 , 95 % CI 1.04 to 3.12 , P = .036 ) . - pubmed
CONCLUSIONS : In patients with a positive g - SPECT scan , GFR is an accurate marker of CAD and is directly correlated to the extent of myocardial ischemia . - pubmed
Drug addiction is a common brain disorder that is extremely costly to the individual and to society . - pubmed
BACKGROUND : Recent studies have indicated that many children with autism spectrum disorders present with language difficulties that are similar to those of children with specific language impairments , leading some to argue for similar structural deficits in these two disorders . - pubmed
METHODS & amp ; PROCEDURES : Adolescents with specific language impairments ( mean age = 15;3 , n = 14 ) and autism spectrum disorders plus language impairment ( autism plus language impairment ; mean age = 14;8 , n = 16 ) were recruited alongside typically developing adolescents ( mean age = 14;4 , n = 17 ) . - pubmed
administration of capsaicin induced dose - dependent mechanical allodynia in wild - type mice ( markedly reducing both the threshold force necessary to induce paw withdrawal and the latency to paw withdrawal induced by a given force ) . - pubmed
Patients with partial response and those with stable disease whose tumor markers decreased by 50 % or more were classified as the effective group . - pubmed
The genomic DNA G+C content of strain NHBX5(T ) was 44.9 mol% . - pubmed
The level of DNA - DNA relatedness between strain NHBX5(T ) and S. - pubmed
Coinfection with Coxiella burnetii in infectious endocarditis . - pubmed
Agrobacterium radiobacter bacteremia in a child with acute lymphoblastic leukemia . - pubmed
BACKGROUND : Agrobacteria are Gram - negative tumorigenic plant pathogens that rarely cause infections in humans . - pubmed
METHODS : The authors describe a 7 - year - old boy with acute lymphoblastic leukemia who carried a central venous catheter and developed bacteremia due to Agrobacterium radiobacter ( A. - pubmed
Catheter removal for the clearance of bloodstream infections due to A. - pubmed
AIMS : Cardiac resynchronization therapy is currently used in selected patients with end - stage heart failure . - pubmed
We report an unusual death of a seemingly healthy 26 - year - old man due to diffuse metastasization of adrenal paraganglioma caused by rupture of the primitive tumour with subsequent massive haemorrhage after a relatively minor trauma . - pubmed
Pulmonary vein isolation alone in patients with persistent atrial fibrillation : an ablation strategy facilitated by antiarrhythmic drug induced reverse remodeling . - pubmed
INTRODUCTION : Pulmonary vein isolation ( PVI ) alone has been thought to be insufficient in patients with persistent atrial fibrillation ( PersAF ) . - pubmed
METHODS AND RESULTS : Seventy - one consecutive patients ( 59.4 + - 9.8 years ) with PersAF and prior AAD failure were treated with oral dofetilide ( 768 + - 291 mcg / day ) for a median of 85 days pre - PVI . - pubmed
Thirty - five patients with paroxysmal ( P ) AF not treated with an AAD served as controls . - pubmed
The 6 and 12 mos AAD - free response to ablation was 76 % and 70 % , respectively , in PersAF patients , similar to the 80 % and 75 % , response in PAF patients ( P = NS ) . - pubmed
A decline in Pdur in response to dofetilide was the only predictor of long - term clinical response to PVI in patients with PersAF . - pubmed
CONCLUSIONS : Pre - treatment with AAD resulted in a decrease in Pdur suggesting reverse atrial electrical remodeling in PersAF patients . - pubmed
Effect of topical glucocorticoid treatment in chinchilla model of lipopolysaccharide induced otitis media with effusion . - pubmed
LPS ( 300 mug ) was injected into the superior bullae of chinchillas to induce OME . - pubmed
After 96 h , chinchillas were euthanized , samples of middle ear effusion ( MEE ) were collected , and temporal bones were removed for histopathological examination . - pubmed
The frequency of patients with hypertension and hyperlipidemia was recorded at 1 year . - pubmed
Oxidative stress and cytotoxicity generated by dental composites in human pulp cells . - pubmed
Pseudomonas aeruginosa is a primary cause of opportunistic infections . - pubmed
Our aim was to study the influence of these polymorphism in study groups with HIV - tuberculosis ( TB ) ( n = 110 ) , TB ( n = 105 ) , and HIV ( n = 130 ) compared with healthy controls ( n = 183 ) , using the tetraprimer amplification refractory mutation system ( ARMS)-polymerase chain reaction method . - pubmed
Chronic gastritis was confirmed in 53.5 % of the patients and 46.5 % had received protom pump inhibitors ( PPIs ) . - pubmed
OBJECTIVE : To compare the prevalence of metabolic syndrome ( MetS ) and its components in second - generation antipsychotic ( SGA)-treated and SGA - naive children ; and to explore the utility of clinical markers , such as waist circumference ( WC ) and body mass index ( BMI ) , as screening tools for MetS. - pubmed
WC measurement is a simple and sensitive screening tool for determining MetS risk in SGA - treated children . - pubmed
Exercise capacity in children with isolated congenital complete atrioventricular block : does pacing make a difference ? - pubmed
Therefore , we have investigated the exercise capacity of a group of contemporary children with CCAVB . - pubmed
Sixteen children ( mean age 11.5 + - 4 ; seven boys , nine girls ) with CCAVB were tested . - pubmed
Hemimaxillectomy patients present with abrupt alterations in the physiologic processes of the maxillae , along with increased anxiety levels due to sudden impairment in esthetics , mastication , speech , deglutition and hypernasal speech . - pubmed
This case report illustrates the multidisciplinary approach to rehabilitate a patient , who had undergone maxillectomy on the right side , due to carcinoma alveolus . - pubmed
Effect of immunotherapy with bapineuzumab on cerebrospinal fluid biomarker levels in patients with mild to moderate Alzheimer disease . - pubmed
PATIENTS : Forty - six patients with mild to moderate Alzheimer disease . - pubmed
Our results show that pretreating rat neonatal cardiomyocytes with NaHS , a H ( 2 ) S donor , reduced the levels of ROS during the hypoxia / reoxygenation ( H / R ) condition . - pubmed
[ Comparative study on tumor cell apoptosis in vitro induced by extracts of Stellera chamaejasme ] . - pubmed
SUMMARY : Advanced diagnostic and therapeutic endoscopic techniques are changing the paradigm of care in patients with early gastric cancers . - pubmed
The haloperidol - induced catalepsy , milk - induced leukocytosis , and nasal provocation in vivo studies in rats proved that the fast - dissolving films of levocetirizine dihydrochloride produced a faster onset of action compared to the conventional tablets . - pubmed
The three H5N2 isolates genetically characterized as low pathogenic AIV were closely related to the strains previously isolated from aquatic wild birds in Japan and also to the Korean strains isolated from aquatic birds in recent years . - pubmed
Rapid eye movement sleep behavior disorder in adults younger than 50 years of age . - pubmed
A rabbit iliac artery injury model was constructed . - pubmed
OBJECTIVE : To investigate factors determining pulmonary vein reconnection in patients undergoing repeat catheter ablation for recurrent atrial fibrillation following cryoballoon ablation . - pubmed
METHODS : Fifty - one consecutive patients undergoing repeat catheter ablation for recurrent atrial fibrillation following initial cryoballoon ablation underwent retrospective assessment of initial cryoablation characteristics , including balloon and vein sizes , venogram occlusion score , balloon freezing time from 0 to -30 C , nadir temperature , and balloon warming time from -30 to +15 C , recorded during the initial cryoballoon procedure . - pubmed
In affected men , LUTS / BPH is believed to result from benign proliferation of the prostate resulting in bladder outlet obstruction . - pubmed
We describe a patient with spontaneous resolution of SFD in DSM documented by serial spectral domain optical coherence tomography ( SD - OCT ) . - pubmed
A 28 - year - old female Japanese patient presented with blurred vision in both eyes . - pubmed
Three months later , the patient achieved spontaneous resolution of SFD without treatment . - pubmed
We report the perioperative course of a patient with long standing ankylosing spondylitis with severe dysphagia due to large anterior cervical syndesmophytes at the level of the epiglottis . - pubmed
Spinal cord injury and contractile properties of the human tibialis anterior . - pubmed
The contractile properties and the fatigability of the tibialis anterior muscle ( TA ) were tested in 8 spinal cord injured ( SCI ) and 8 control individuals . - pubmed
All indices of contractile speed were slower in the spinal cord injured subjects than in the controls . - pubmed
METHODS : A total of 120 UC patients and 125 age and sex matched controls with no GI symptoms were enrolled . - pubmed
RESULTS : Out of the 120 UC patients , 74 were male with mean+-SD age of 45.6 + -17.5years . - pubmed
LPO in UC patients was significantly increased ( p<0.01 ) while GSH was significantly decreased ( p<0.01 ) as compared to controls . - pubmed
OCTT and SIBO were significantly higher in UC patients as compared to controls . - pubmed
Minocycline , a microglial inhibitor , diminishes terminal patients ' delirium ? - pubmed
OBJECTIVES : The aim of this study was to investigate specific fears related to hypoglycemia in adults with type 1 diabetes and to investigate how aspects of fear of hypoglycemia may differ between genders . - pubmed
METHODS : A cross - sectional study with questionnaires sent to 636 patients with type 1 diabetes , aged 18 - 75 years , who attended the outpatient clinic at St. Olavs Hospital , Trondheim , Norway . - pubmed
Rodent models of juvenile stress appear to support this hypothesis because juvenile stress can result in reduced activity / exploration and enhanced anxiety , although results are not always consistent . - pubmed
RESULTS : Nine colistin - resistant strains were detected in a collection of 739 enterobacteria ( S. - pubmed
METHODS : This randomized clinical trial was conducted on 90 asthmatic patients who were randomly divided into inhalation technique group with spacer , inhalation technique group without spacer , and a control group . - pubmed
Differential prognostic impact of resting heart rate in older compared with younger patients with chronic heart failure -- insights from TIME - CHF . - pubmed
BACKGROUND : There is little information regarding the prognostic role of resting heart rate ( HR ) in older compared with younger patients with chronic heart failure ( HF ) . - pubmed
METHODS AND RESULTS : In patients enrolled in the Trial of Intensified Medical Therapy in Elderly Patients With Congestive Heart Failure ( TIME - CHF ) with sinus rhythm , effects of baseline HR ( & gt;=70 vs & lt;70 beats / min [ bpm ] ) on 18 - month outcomes were compared between older ( & gt;=75 years ; n = 186 ) and younger ( & lt;75 years ; n = 141 ) patients . - pubmed
CONCLUSIONS : In contrast to HF patients aged & lt;75 years , we found no association between HR and worse outcomes in HF patients aged & gt;=75 years . - pubmed
OBJECTIVES : To compare the treatment efficacy of intravitreal bevacizumab ( IVB ) and the combination of IVB and intravitreal triamcinolone ( IVT ) for DME patients . - pubmed
BACKGROUND : Radial artery ( RA ) occlusion ( RAO ) is not rare in patients undergoing coronary intervention by transradial approach ( TRCI ) . - pubmed
METHODS : Between June 2006 and March 2010 , all patients who underwent TRCI were classified according to the weakness of RAP after removing compression bandage with confirmation by Doppler ultrasound for the first 30 consecutive patients . - pubmed
There were two patients experienced persistent RAO with a success rate of 98.9 % and RAO in 0.075 % of patients after ulnar artery compression was applied . - pubmed
The group of Negative - Stranded RNA Viruses ( NSVs ) includes many human pathogens , like the influenza , measles , mumps , respiratory syncytial or Ebola viruses , which produce frequent epidemics of disease and occasional , high mortality outbreaks by transmission from animal reservoirs . - pubmed
We assessed role of MBL deficiency in HIV-1 and schistosoma infections in Zimbabwean adults enrolled in the Mupfure Schistosomiasis and HIV Cohort ( MUSH Cohort ) . - pubmed
Further , EIAV infection can cause lesions on the spleen and lymph nodes , similar to those frequently observed in horses , the natural hosts . - pubmed
Protection of testis through antioxidant action of Mallotus roxburghianus in alloxan - induced diabetic rat model . - pubmed
About 90 % of diabetic patients have been associated with reproductive impairments . - pubmed
roxburghianus was given to male albino Wistar rats by oral gavage to study the acute toxicity . - pubmed
CONCLUSION : MRME treatment to diabetic rats improves diabetes induced oxidative damage in testis as well as provides protection to testis . - pubmed
Gait variability in multiple sclerosis : a better falls predictor than EDSS in patients with low disability . - pubmed
This longitudinal study aims to compare the role of stride time variability ( STV ) and EDSS for predicting falls in 50 patients with multiple sclerosis with low disability . - pubmed
To show the potential of the plugin we have applied it in a study of two miRNAs that are particularly relevant in human melanoma progression , miR-146a and miR-214 . - pubmed
Hypoglycemia is a very common in type 1 diabetic persons and can occur at any age . - pubmed
It is always threatening to the well - being of patients with Type 1 diabetes mellitus ( T1DM ) since hypoglycemia leads to seizures or loss of consciousness and the possible development of permanent brain dysfunction under certain circumstances . - pubmed
Because of that , an accurate continuing hypoglycemia monitoring system is a very important medical device for diabetic patients . - pubmed
A clinical study of 16 children with T1DM is given to illustrate the good performance of ELM . - pubmed
Newborn human infants display robust pain behaviour and specific cortical activity following noxious skin stimulation , but it is not known whether brain processing of nociceptive information differs in infants and adults . - pubmed
These data support our hypothesis and indicate important postnatal changes in the encoding of mechanical pain in the human brain . - pubmed
Efficacy of a single dose of trazodone hydrochloride given to cats prior to veterinary visits to reduce signs of transport- and examination - related anxiety . - pubmed
OBJECTIVE To evaluate the efficacy of a single dose of trazodone for reducing anxiety in cats during transport to a veterinary hospital and facilitating handling during veterinary examination . - pubmed
ANIMALS 10 healthy client - owned cats ( 2 to 12 years of age ) with a history of anxiety during transport or veterinary examination . - pubmed
Owners scored their cat 's signs of anxiety before , during , and after transport and examination . - pubmed
RESULTS Compared with placebo , trazodone resulted in a significant improvement in the cats ' signs of anxiety during transport . - pubmed
CONCLUSIONS AND CLINICAL RELEVANCE Oral administration of a single dose of trazodone to cats prior to a veterinary visit resulted in fewer signs of transport- and examination - related anxiety than did a placebo and was generally well tolerated by most cats . - pubmed
METHODS : Scar fibroblasts were isolated from deprecated human hypertrophic scar tissue and then sub - cultured . - pubmed
Then human hypertrophic scar tissue was embedded into the incision . - pubmed
Tobacco smoking has been linked as a risk factor for TB . - pubmed
MATERIALS AND METHODS : Pulmonary TB patients aged between 18 and 65 years were enrolled and followed - up until treatment completion . - pubmed
Cardio - Thoracic Ratio Is Stable , Reproducible and Has Potential as a Screening Tool for HIV-1 Related Cardiac Disorders in Resource Poor Settings . - pubmed
OBJECTIVES : The preferred countermeasure to avoid exercise - related hypoglycemia was investigated in a group of patients with type 1 diabetes participating in a stressful event , a 24x1 - hour relay marathon . - pubmed
Glycemia fell by the end of the races ( p=0.006 ; median -1.8 mmol L-1 ; interquartile range -0.4 mmol L-1 to -5.3 mmol L-1 ) , despite 9 patients being hyperglycemic at the start . - pubmed
Of the patients , 14 concluded the race with glycemia on target , and 4 patients were hyperglycemic . - pubmed
However , the snail Eobania vermiculata possesses a diverticulum that is three times longer than the spermatophore it receives . - pubmed
Here , we report that the love - dart mucus of this species contains a contraction - inducing substance that shortens the diverticulum , an effect that is only properly revealed when the mucus is applied to another helicid species , Cornu aspersum This finding suggests that E. - pubmed
Effect of various selenium doses on chromium ( IV )-induced nephrotoxicity in a male chicken model . - pubmed
This study demonstrated that Cr ( VI ) can result in kidney oxidative damage in male chickens , and Se of certain dose has the protective effects against Cr ( VI )-induced nephrptoxicity . - pubmed
OBJECTIVE : Alchornea floribunda leaves are widely used in ethnomedicine for the management of immuno - inflammatory disorders . - pubmed
17beta - Estradiol prevents mesenteric injury induced by occlusion of the proximal descending aorta in male rats . - pubmed
Therefore , this study investigated the role of 17beta - estradiol on visceral ischemia - reperfusion ( I / R ) injury after descending aorta occlusion in male rats . - pubmed
METHODS : Mesenteric ischemia was induced in male Wistar rats by placing a 2F Fogarty arterial embolectomy catheter ( Edwards Lifesciences , Irvine , Calif ) in the descending aorta , which remained occluded for 15 minutes , followed by reperfusion for up to 2 hours . - pubmed
Rats were divided into four groups : ( 1 ) rats that underwent surgical manipulation only ( sham , n = 22 ) ; ( 2 ) rats that underwent I / R injury ( n = 22 ) ; ( 3 ) rats treated with intravenous 17beta - estradiol ( 280 mug / kg ) 30 minutes before I / R ( n = 22 ) ; ( 4 ) or at the beginning of reperfusion ( n = 22 ) . - pubmed
However , the depletion of intragraft B cells during acute rejection did not affect steroid resistance , proteinuria , graft function at 2 years follow - up , or patient and graft survival at a median follow - up of 4.1 years ( range , 2.0 - 6.2 years ) . - pubmed
CASE DESCRIPTION : A 16 year - old female who presented with initial ear , nose and throat manifestations who later progressed to severe renal disease , requiring hemodialysis after 11 months of unique laryngeal involvement . - pubmed
Adult patients with irretrievable CBDS who had plastic stent insertions throughout the follow - up period were included . - pubmed
In the ESE group , 4/28 patients had duct clearance in subsequent ERCPs , 1/28 patient presented with a blocked stent , and no biliary - related deaths were observed . - pubmed
Postoperative disseminated intravascular coagulation in a pregnant patient with Blue Rubber Bleb Nevus Syndrome presenting with acute intestinal obstruction : Case report and literature review . - pubmed
This is the first report of a life - threatening postoperative disseminated intravascular coagulation in such patients . - pubmed
CASE PRESENTATION : Twenty - five year - old female pregnant patient presents to the emergency department with colicky pain and oligohydramnios . - pubmed
CONCLUSION : This rare presentation of acute intestinal intussusception in a patient with Blue Rubber Bleb Nevus Syndrome was further complicated with postoperative coagulation disorder . - pubmed
Thirty - two patients with ankylosing spondylitis were recruited in the experimental group and 36 normal individuals were recruited to the control group . - pubmed
BACKGROUND : To prevent hypocalcemia , this study examined the efficiency of a calcium supplement formula guided by predicted calcium requirement in patients with renal failure after parathyroidectomy with autotransplantation . - pubmed
treatment of the triple transgenic ( APPsw / PS1M146V / TauP301L ) mice with M344 , at doses as low as 3 mg / kg , significantly prevented cognitive decline evaluated by Y - maze spontaneous alternation , novel object recognition , and Barnes maze spatial memory tests . - pubmed
A case of human ocular dirofilariasis in a patient with multiple endocrine neoplasia in Northwest Spain . - pubmed
Effect of intramural fibroid on uterine and endometrial vascularity in infertile women scheduled for in - vitro fertilization . - pubmed
METHODS : 3D power Doppler was used to measure the endometrial volume and blood flow indices in 182 women with intramural fibroids not affecting the uterine cavity and compared them to a matched control group without fibroids . - pubmed
Women with fibroids & gt ; 4 cm had a significantly higher Endometrial FI ( p = 0.037 ) , and VFI ( p = 0.02 ) . - pubmed
21 - gene recurrence assay in patients receiving intraoperative radiotherapy : are " favorable " characteristics a surrogate for low recurrence ? - pubmed
Conclusions : Most patients selected for IORT based on clinical features were indeed low risk based on RS . - pubmed
All three dogs incurred rectal wall compromise during surgical excision of anal sac tumours . - pubmed
The model suggests that the best way to treat AD is to prevent synaptic separation by identifying individuals experiencing unusually high rates of ventricle growth and reducing this to more normal levels by shunting or some other technique . - pubmed
Cutaneous non - epitheliotropic T - cell lymphoma associated with a fracture site in a cat . - pubmed
Case summary : A 7 - year - old male neutered domestic shorthair cat presented for investigation of a swelling over the right forelimb . - pubmed
A 70 's man underwent subtotal stomach preserving pancreatoduodenectomy(SSPPD)for pancreatic head cancer . - pubmed
Cross - sectional studies show that exercise advantage is lost in oligo - amenorrheic athletes ( OA ) . - pubmed
Longitudinal studies examining the opposing effects of exercise and hypogonadism on bone are lacking in adolescents / young adults . - pubmed
Wheat Intolerance and Chronic Gastrointestinal Symptoms in an Australian Population - based Study : Association Between Wheat Sensitivity , Celiac Disease and Functional Gastrointestinal Disorders . - pubmed
The aims of this study were to determine the prevalence of self - reported wheat or gluten sensitivity and doctor diagnosed CD in an Australian population , define the associated gastrointestinal ( GI ) symptoms and FGIDs , and determine the relationship between self - reported wheat sensitivity , demographic and medical factors . - pubmed
We defined self - reported wheat sensitivity as people who reported gastrointestinal symptoms on ingestion of wheat based foods , but did not suffer from celiac disease , inflammatory bowel disease or colorectal cancer . - pubmed
Infliximab for pediatric patients with Crohn ' s disease : A Phase 3 , open - label , uncontrolled , multicenter trial in Japan . - pubmed
This study aimed to investigate the efficacy , safety , and pharmacokinetic profile of infliximab ( IFX ) in pediatric patients with moderate - to - severe CD and inadequate response to existing treatment . - pubmed
Pediatric patients ( aged 6 - 17 years ) with moderate - to - severe CD were treated with IFX 5 mg / kg at Weeks 0 , 2 , and 6 , and at 8 - week intervals thereafter until Week 46 , with final evaluation at Week 54 . - pubmed
CONCLUSIONS : These findings support the effective use of IFX in the treatment of pediatric patients with CD where other treatments have proven ineffective . - pubmed
Investigating the Molecular Mechanism of Aqueous Extract of Cyclocarya paliurus on Ameliorating Diabetes by Transcriptome Profiling . - pubmed
The aqueous extract of Cyclocarya paliurus leaves ( CPAE ) was reported to be anti - diabetic . - pubmed
To elucidate the anti - diabetic effects of CPAE and the underlying potential mechanisms , we performed transcriptome profiling ( RNA - Seq and miRNA - Seq ) on the pancreas and liver from non - diabetic , diabetic and diabetic - CPAE rats . - pubmed
Sasa veitchii extract protects against carbon tetrachloride - induced hepatic fibrosis in mice . - pubmed
Complete improvement after medical treatment was only described in patients with DBH and minimal SHR ( p = 0.001 ) . - pubmed
Treatment success was defined as simultaneous fulfillment of 3 criteria : improvement in pain , expectations for surgery met , and patient satisfied with surgery . - pubmed
Most patients showed improvement in pain ( & gt;=88 % ) and high satisfaction ( & gt;=93 % ) and expectation fulfillment ( & gt;=80 % ) postoperatively . - pubmed
The complex of its antiviral properties and the results of its exhaustive preclinica study , as well as the results of studying its safety and tolerability in adult HIV - infected patients , including important first data of its use as a specific therapeutic antiHIV / AIDS drug , certainly indicate on its prospects and its usefulness in clinical use in patients with HIV infection , including as part of combination antiretroviral therapy . - pubmed
RESULTS : 265 patients were enrolled and 82 ( 30.9 % ) developed severe AKI - defined according to KDIGO stage 2/3 . - pubmed
Integrated HIV DNA decline after immunotherapy was also associated with gene expression patterns indicative of cell - mediated activation and NK cytotoxicity . - pubmed
METHODS : Twenty - five symptomatic adolescents aged between 12 and 19 years with a recent ( within 10 days ) SRC and 22 healthy controls aged 13 to 20 years were assessed using the vHIT , Balance Error Scoring System ( BESS ) , and Vestibular Ocular Motor Screening ( VOMS ) tools . - pubmed
RESULTS : VOR gain in all adolescents with SRC was greater than 0.8 , which is considered within normal limits . - pubmed
CLINICAL RELEVANCE : We do not recommend the assessment of head impulse function in adolescents with SRC unless more definitive signs of peripheral vestibular injury are present . - pubmed
We recommend using the VOMS to assess symptoms of suspected SRC injury in adolescents . - pubmed
in vitro cytotoxicity assays showed selective activity of HA - spacer - oliHA conjugates against cancer cell lines in comparison with standard human fibroblasts . - pubmed
The overall rate of biliary stricture resolution was 44.8 % ( 43 of 96 patients ) with a median follow - up duration of 90.9 months ( interquartile range , 30.9 - 122.3 months ) . - pubmed
After successful endoscopic treatment , biliary strictures recurred in 22 patients ( 57.9 % ) after BD , and in one patient ( 4 % ) after PS treatment . - pubmed
CONCLUSIONS : Despite a high technical success rate , endoscopic treatment only provided a low rate of resolution of anastomotic biliary strictures among LDLT patients and required prolonged treatment duration . - pubmed
Participants were 188 ( 97 in intervention group and 91 in control group ) people with HIV and mild to moderate depressive symptoms recruited in HIV treatment centers in the Netherlands . - pubmed
In addition , no significant change was observed in body weights , yolk sac weight and relative weight organs except the liver and kidney were significantly increased with groups treated with glyphosate and Roundup compared to the control group . - pubmed
BACKGROUND / AIMS : To assess risk factors for serous retinal detachment ( SRD ) in the fellow eye of patients with central serous chorioretinopathy ( CSC ) based on clinical data and multimodal imaging findings , including baseline late - phase indocyanine green angiography ( ICGA ) . - pubmed
METHODS : Consecutive patients with unilateral CSC were retrospectively assessed . - pubmed
RESULTS : Sixty - eight patients with unilateral CSC were included . - pubmed
CONCLUSION : These results suggest that the fellow eyes with specific findings on multimodal imaging in patients with unilateral CSC should be carefully followed up for possible incidence of CSC . - pubmed
Fluorescence In Situ Hybridization ( FISH ) Detection of Viral Nucleic Acids in Oncolytic H-1 Parvovirus - Treated Human Brain Tumors . - pubmed
The primary purpose of the trial was to evaluate the safety of an oncolytic parvovirus , H-1PV ( ParvOryx ) , in recurrent glioblastoma patients . - pubmed
The FISH method allowed the detection - for the first time in humans - of H-1PV replication markers in brain tumors of parvovirus - treated patients . - pubmed
Associations between model - predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the treatment of venous thromboembolism . - pubmed
The first outbreak of ZIKV was reported in 2007 in the Pacific area followed by another severe outbreak , which occurred in 2013/2014 and subsequently , ZIKV spread to all other Pacific islands . - pubmed
A broad spectrum of ZIKV associated neurological malformations in neonates and adults have driven this deadly virus into the limelight . - pubmed
Though tremendous efforts have been focused on understanding the molecular basis of ZIKV , the viral proteins of ZIKV have still not been studied , extensively . - pubmed
Hepatic involvement in COVID-19 patients : Pathology , pathogenesis , and clinical implications . - pubmed
We develop a mathematical model for fitness landscapes generated by such tradeoffs , based on experiments that determine the antibiotic dose - response curves of Escherichia coli strains , and previous observations on antibiotic resistance mutations . - pubmed
RESULTS : In the HTK group , 52 patients ( 40 % ) exhibited either PGD or PGNF , compared to 20 patients ( 31 % ) in the IGL-1 group ( P = .208 ) . - pubmed
Patients from the HTK group had higher mean values for cryoprecipitate transfusion ( P = .0064 ) , first day serum lactate ( P = .0099 ) , higher incidence of vascular complications ( 11 % vs 2 % in the IGL-1 group ; P = .0226 ) , but a lower incidence of infection ( 7 % vs 28 % in the IGL-1 group ; P < .0001 ) . - pubmed
CONTEXT : Nonalcoholic fatty liver disease ( NAFLD ) is the most common cause of liver disease , affecting approximately 3 in 10 obese children worldwide . - pubmed
METHODS : Patients who had low back pain radiating to the leg , were preoperatively diagnosed with cLDH by computed tomography and/or magnetic resonance imaging , and were treated with a surgical decompression procedure were studied . - pubmed
The patients developed few postoperative complications and no recurrence during 1 year of follow - up . - pubmed
CONCLUSION : Our data suggest that the decompression approach is effective for management of cLDH at least in the short term ( 1 year ) with respect to reducing pain and improving patient satisfaction with few complications . - pubmed
We propose that appropriate animal models of human pregnancy complications must be established in the PEV field . - pubmed
In this study , we generated rat models of septic shock induced by lipopolysaccharide . - pubmed
METHODS : We performed a retrospective multicenter study including all CD patients with a non - passable symptomatic UGT stricture on endoscopy . - pubmed
RESULTS : 60 CD patients with an UGT stricture were included . - pubmed
Rapid rehabilitation nursing improves clinical outcomes in postoperative patients with colorectal carcinoma : A protocol for randomized controlled trial . - pubmed
Surgical treatment is widely performed in patients with colorectal carcinoma . - pubmed
CONCLUSION : The research can offer a reliable basis for the effectiveness of a rapid recovery nursing program in patients with colorectal carcinoma . - pubmed
SARS - CoV-2 - related rapid reorganization of an epilepsy outpatient clinic from personal appointments to telemedicine services : A German single - center experience . - pubmed
Overall , 9.2 % ( n = 10 ) of patients reported general supply problems due to SARS - CoV-2 , and 28.4 % ( n = 31 ) reported epilepsy - specific problems , most frequently related to prescriptions , or supply problems for antiseizure drugs ( ASDs ; 22.9 % , n = 25 ) . - pubmed
In this article , we evaluated the structural neuro - retinal abnormalities , especially the thickness in the ganglion cell complex ( GCC ) , in patients with mitochondrial myopathy , encephalopathy , lactic acidosis and stroke - like episodes ( MELAS ) . - pubmed
The GCC thickness in MELAS patients was significantly thinner than that in normal controls even when they had no history of transient homonymous hemianopia . - pubmed
In conclusion , OCT may be an effective tool to monitor and predict disease progression in MELAS patients . - pubmed
Patients with suspected sepsis were evaluated for multi organ dysfunction . - pubmed
Cell reaction of the interstitial tissue in the aseptic inflammation areas was studied to determine the nonspecific reactivity of the organism in patients with infiltrative tuberculosis of the lungs . - pubmed
Preoperative irradiation in the VASAG studies resulted in downstaging in terms of operative findings of lymph node involvement and was of survival benefit in those patients have an AP resection for cure or palliation of rectal cancer ( P less than 0.02 ) . - pubmed
Principal features of the complex results include : double peaks in the time course of convulsion thresholds ( Pc ) ; an early peak and a shoulder in the time course of pressures reversing anesthesia ( Pa ) ; far steeper dose - response curves for Pa than for Pc ; selectively greater anticonvulsant effect for phenobarbital than for the other barbiturates ; and enhancement of Pa with simultaneous depression of Pc by reserpine in phenobarbital - pretreated mice . - pubmed
All staphylococcal strains were inhibited by 4 micrograms of RP 59500 per ml , including multiply resistant strains . - pubmed
Thirty - six intensive care unit patients , receiving aseptic or manually ( routine ) reconstituted enteral feeding formulas , were evaluated prospectively for the relationship of microbial involvement , gastric pH , and antimicrobial therapy to diarrhea . - pubmed
There were no significant direct associations between isolate category ( Gram - negative bacilli , Gram - positive cocci , Gram - negative cocci , yeast ) , gastric pH , or antimicrobials and diarrhea . - pubmed
However , two organisms ( Group D Enterococci and yeast ) were indirectly implicated in some cases of diarrhea . - pubmed
Clinical deterioration in patients with idiopathic pulmonary fibrosis : causes and assessment . - pubmed
In evaluating clinical deterioration in patients with IPF , disease - associated complications and adverse effects of therapy should be distinguished from progressive pulmonary fibrosis . - pubmed
The cause of clinical deterioration will alter the therapeutic intervention required and will influence patient prognosis and duration of survival . - pubmed
This article examines the causes of clinical deterioration in patients with IPF and the diagnostic procedures for assessing disease - associated complications and staging IPF progression . - pubmed
Antibodies to staphylococcal peptidoglycan and its peptide epitopes , teichoic acid , and lipoteichoic acid in sera from blood donors and patients with staphylococcal infections . - pubmed
Antibodies to the staphylococcal antigens peptidoglycan , beta - ribitol teichoic acid , and lipoteichoic acid , as well as to the peptidoglycan epitopes L - Lys - D - Ala - D - Ala , L - Lys - D - Ala , and pentaglycine , were found over a wide range of concentrations in sera from both blood donors and patients with verified or suspected staphylococcal infections . - pubmed
A 30 - year old man who for several years had been hypertensive was admitted for attacks of paroxysmal hypertension . - pubmed
On the other hand , three patients with in situ duct carcinoma ( one comedo and two clinging type ) developed subsequent invasive carcinoma . - pubmed
Catecholamine activity in paraventricular hypothalamus after hemorrhage in cats . - pubmed
Temporal changes in catecholamine activity within the paraventricular nucleus ( PVN ) of the hypothalamus were assessed using in vivo voltammetry after moderate hemorrhage in chloralose - anesthetized cats . - pubmed
Because cloning cDNA copies of HPV mRNAs recovered from human lesions has met with only very limited success , the characterization of HPV mRNAs has been problematic . - pubmed
In comparisons among groups , the Tweed patients generally exhibited the greatest lower lip retraction . - pubmed
[ Bacteroides fragilis meningitis . - pubmed
In this study based on 2 personal cases and 23 cases from the literature the main clinical and therapeutic features of meningitis caused by Bacteroides fragilis are reviewed . - pubmed
It is found the PGE content in the gastric mucosa and plasma is increased in all patients with gastric cancer , especially with signet ring cell carcinoma . - pubmed
It is higher in the regional lymph node metastasis than in the early cancer , extensive metastases and normal subjects . - pubmed
There is no significant difference in extensive metastases , relapse free and normal subjects . - pubmed
inoculation of tumor cells ( 5 - 10 x 10(4)/mouse ) . - pubmed
Sixty - three patients presenting with the clinical problem of renal outflow disorder were studied using 99mTc DTPA . - pubmed
[ Survival of 17 patients with inoperable bronchial cancer , treated with cytostatic drugs and radiation in minimal useful doses ] . - pubmed
[ Contribution to the study of philometrosis in carp ] . - pubmed
Canine Filaroides osleri and Filaroides milksi infection . - pubmed
Tuberculosis should be suspected in immunosuppressed patients suffering from pyrexia of unknown origin , even when chest X - ray is normal . - pubmed
Diet - dependent hyperplastic growth of adipose tissue in hypothalamic obese rats . - pubmed
Accelerated production of fat cells is often seen in dietary obesity in rats but not in obesity occurring in response to damage to the medial area of the hypothalamus ( MH ) . - pubmed
MH damage ( MHD ) was produced in rats by either electric current or small knife cuts . - pubmed
Fat cell production did not accelerate during the 1st 16 wk after MHD in rats fed only chow , but acceleration clearly occurred in rats fed HFS during only 4 wk . - pubmed
However , there was greater acceleration after MHD in HFS - fed rats held to the same weight gain as chow - fed rats . - pubmed
Rats allowed to freely eat HFS for 6 mo after MHD showed extremely large increases in body weight and fat cell number . - pubmed
The plateau in body weight often seen in rats fed only chow after MHD did not occur . - pubmed
These findings suggest that enlargement of fat cells and components of the diet act synergistically in the promotion of adipocyte hyperplasia in adult rats and also suggest that accelerated weight gain after MHD is not due to elevation of a set point for body weight or body fat . - pubmed
Heat - induced protection of mice against thermal death . - pubmed
We used C3H mice to investigate whether whole - body heating can be used as a conditioning treatment to induce protection of mice against thermal death from a subsequent heat treatment . - pubmed
It is suggested that the myocardial ischaemic defence , as worked out by nature herself , in the diving seal has important implications for the treatment of acute myocardial ischaemia in man . - pubmed
Masses of crystals , which were largely composed of cholesteryl esters , were found in a porcine aortic valvular bioprosthesis removed eight years after implantation in the mitral position in a patient with rheumatic mitral valvular stenosis . - pubmed
These cholesterol deposits are most likely derived from blood lipids ; however , they were not related to hyperlipidemia , since the patient had normal blood levels of cholesterol and triglycerides . - pubmed
To assess the effects of radiation therapy on the specific red cell adherence test we have evaluated 33 patients who underwent cystectomy for bladder cancer and in whom radiotherapy had been used . - pubmed
These findings strongly suggest that 1 ) the specific red cell adherence test does remain negative after radiotherapy and 2 ) this test is a valuable prognosticator of the future likelihood of invasion in all patients with transitional cell carcinoma of the bladder . - pubmed
Endothelium - dependent relaxation of small arteries from essential hypertensive patients : mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously hypertensive rats . - pubmed
Impaired endothelium - dependent relaxation has been previously demonstrated in blood vessels of hypertensive rats and in humans with essential hypertension . - pubmed
The mechanisms involved in endothelium - dependent relaxation of human arteries are unclear , and the potential generation of endothelium - derived contracting factor by endothelium in human hypertension has not been established . - pubmed
We investigated the effects of acetylcholine on precontracted small arteries dissected from gluteal subcutaneous fat biopsies from normotensive subjects and subjects with borderline and mild essential hypertension . - pubmed
Vessels from normotensive subjects and those from borderline hypertensive patients , precontracted by noradrenaline , were relaxed completely by acetylcholine , whereas those from patients with mild essential hypertension relaxed slightly but significantly less , indicating that generation of endothelium - derived relaxing factor ( endothelium - derived nitric oxide ) was only minimally reduced or that production of minor amounts of endothelium - derived contracting factor occurred in small arteries from these hypertensive subjects . - pubmed
This impairment of endothelium - dependent relaxation was not corrected by indomethacin , which indicated that the contribution of endothelium - derived contracting factor , if any , was minimal in this subset of essential hypertensive patients . - pubmed
In contrast , mesenteric small arteries of adult spontaneously hypertensive rats presented strong contractions in response to the higher concentrations of acetylcholine , which were abolished by exposure to indomethacin . - pubmed
The authors studied 32 primary uveal melanomas from 32 patients ( among these , 12 were rapidly metastasizing and 16 slowly metastasizing ) and 29 metastases from 19 patients . - pubmed
From 13 patients the primary , as well as the metastatic , tumors were available . - pubmed
Ventilatory and metabolic responses to hypoxia in the echidna , Tachyglossus aculeatus . - pubmed
We examined 29 eyes of 15 patients with Harada disease using ICG angiography . - pubmed
In 3 patients , the area of retinal detachment showed hypofluoresence in the late phase . - pubmed
The studies using immunofluorescence test showed that the percentage of HHV-6 - infected subjects was practically similar among blood donors , patients with nasopharyngeal cancer , rheumatoid arthritis , hemophilia , and patients with transplanted kidney , varying from 34 % to 49 % . - pubmed
A significantly higher per cent ( 66 % ) and higher antibody titres to HHV-6 were detected in sera from patients with hemoblastoses . - pubmed
If we look at patients with correct diagnosis of syncope ( 183 patients ) the mortality rate is 8.19 % ( if we consider those aged & gt ; 65 the rate is 17.44 % ) . - pubmed
Operative treatment is indicated when conservative management for at least 6 months has been unsuccessful and subluxation continues to occur during everyday activities , but it should never be instituted in patients with emotional disorders . - pubmed
METHODS : One hundred thirty - four limbs of 123 unselected patients who arrived in the outpatient clinic with residual or recurrent varicose veins after undergoing an operation were included . - pubmed
Prevalence of Helicobacter pylori in acromegalic patients during treatment with octreotide . - pubmed
In acromegalic patients treated with octreotide there is an increased incidence of gallstones and possibly gastritis . - pubmed
OBJECTIVES : ( 1 ) To compare the seroprevalence of Helicobacter pylori ( H. pylori ) infection , in acromegalic patients treated with octreotide to that in patients given other treatment modalities . - pubmed
PATIENTS : Three groups of acromegalic patients were studied ; 35 ( 20 M ) had been treated with octreotide , 17 ( 10 M ) with bromocriptine and 19 ( 12 M ) had received no pharmacological intervention ( untreated , surgically treated or treated with radiotherapy ) . - pubmed
To investigate this issue , the influence of either standard reoxygenation or transient hyperoxia was studied on the consequences of severe hypoxia in a model of cultured neurons isolated from the fetal rat brain . - pubmed
Animal models for the study of perinatal hypoxic - ischemic encephalopathy : a critical analysis . - pubmed
We critically evaluated various design features from 292 animal studies related to perinatal hypoxic - ischemic encephalopathy ( HIE ) . - pubmed
Rodents were the most frequently used animals in HIE research ( 26 % ) , followed by piglets ( 23 % ) and sheep ( 22 % ) . - pubmed
While no single animal model was found to be ideal for all HIE research , some models were distinctly superior to others , depending upon the specific research question . - pubmed
Experimental infection of 10 juvenile P. - pubmed
METHOD : We photodocumented the evolution of a full - thickness macular hole in a patient who refused surgery . - pubmed
RESULTS : A 60 - year - old woman , who had had difficulty reading for 3 months , was initially examined with a stage 1B macular hole in her right eye that progressed to stage 2 over a 6 - month period and then to stage 3 , 2 years after initial examination . - pubmed
Insulin resistance and increased fat mass ( FM ) are common in human aging . - pubmed
Histopathological and clinical studies indicate that areas of choroidal ischemia often are seen near CNVs in AMD patients . - pubmed
Sexual dysfunction related to antihypertensive agents : results from the animal model . - pubmed
In order to delineate the direct drug effects from vascular insufficiency inherent in hypertensive states , the study was conducted on a normotensive animal model . - pubmed
The palliative procedure of partial gastrectomy , gastroenterostomy shunt and trophic fistula was carried out 117 patients . - pubmed
This review focuses on the developmental biology of human bone marrow B - lineage cells , including perturbations that contribute to the origin and evolution of B - lineage acute lymphoblastic leukemia and primary immunodeficiency diseases characterized by agammaglobulinemia . - pubmed
The triad of laboratory models that mimic the bone marrow microenvironment , immunodeficiency diseases with specific defects in B - cell development , and B - lineage acute lymphoblastic leukemia can now be integrated to deepen our understanding of human B - cell development . - pubmed
Finally , we discuss their potential use for stratification of patients with acute coronary syndromes with respect to optimal treatment , resource - saving monitoring , and more precise prognostication . - pubmed
OBJECTIVE : To determine the safety and efficacy of glycopyrrolate in the treatment of developmentally disabled children with sialorrhea . - pubmed
PATIENTS : Thirty - nine children with both developmental disabilities and excessive and bothersome sialorrhea . - pubmed
CONCLUSIONS : Glycopyrrolate is effective in the control of excessive sialorrhea in children with developmental disabilities . - pubmed
Structural conformers produced during malaria vaccine production in yeast . - pubmed
METHODS : From 1980 to 1997 , 477 patients were operated on for thoracic or intrathoracic tuberculosis in Laennec Hospital , Paris ( 259 suffered lung diseases ) . - pubmed
Surgery was performed for a therapeutic purpose in 104 patients with sequelae , and in 10 patients with active tuberculosis ( pneumonectomy , n = 19 ; pleuropneumonectomy , n = 19 ; lobectomy , n = 54 ; and segmentectomy , n = 22 ) . - pubmed
Tumour enhancement with newly developed Mn - metalloporphyrin ( HOP-9P ) in magnetic resonance imaging of mice . - pubmed
Stress of chronic food restriction attenuates the development of adjuvant arthritis in male Long Evans rats . - pubmed
OBJECTIVE : To study the effect of the stress of chronic food restriction on the development of adjuvant arthritis in Long Evans male rats . - pubmed
The body weight of the animals was recorded on day 0 , 3 , 7 , 11 , 15 and 18 of the disease . - pubmed
Eosinophilic leukocytes accumulate in high numbers in the lungs of asthmatic patients , and are believed to be important in the pathogenesis of asthma . - pubmed
METHODS : CML cell line K562 and fresh bone marrow cells from 6 untreated Ph+ CML patients were used for in vitro culture study . - pubmed
Assessing disturbed thinking and cognition using the Ego Impairment Index in older schizophrenia patients : paranoid vs. nonparanoid distinction . - pubmed
RESULTS : Nonparanoid schizophrenia patients demonstrated significantly greater impairment on the EII than their paranoid counterparts . - pubmed
The EII performance of paranoid patients was similar to normal comparison participants . - pubmed
Furthermore , the paranoid patients displayed better premorbid intellectual functioning , less negative symptoms , and better global cognitive performance than nonparanoid patients . - pubmed
Rats were injected with lipopolysaccharide for induction of experimental gram - negative sepsis . - pubmed
Evidence from randomized trials now shows a survival advantage for the use of PBSC in patients with advanced leukaemia . - pubmed
The same GAGs were decreased in the skin of fasted rats . - pubmed
Relative contribution of mucosal injury and Helicobacter pylori in the development of gastroduodenal lesions in patients taking non - steroidal anti - inflammatory drugs . - pubmed
METHODS : We used multivariate regression analyses of three large similar trials to identify factors that placed patients at high risk of ulcer development or relapse . - pubmed
We compared the efficacy of omeprazole 20 mg daily , misoprostol 200 micro g twice daily , and ranitidine 150 mg twice daily in preventing ulcers and erosions at different sites and in patients who were H pylori positive and negative . - pubmed
RESULTS : Patients with endoscopic lesions ( which healed ) initially were significantly more likely than those without to develop further erosions or ulcers during treatment ( rate ratio 2.12 , 1.07 - 4.17 ) . - pubmed
This advantage was especially evident in H pylori positive patients receiving acid suppression ( 5.7 % v 16.6 % for gastric ulcer with omeprazole ) . - pubmed
CONCLUSIONS : Relapse of lesions in patients taking NSAIDs was highly site and type specific and not adversely affected by H pylori status . - pubmed
This strongly implies that local mucosal factors predispose to ulcer development in patients taking NSAIDs . - pubmed
Trigeminal pain processing was studied in 14 patients with unilateral migraine attacks and 14 age- and sex - matched patients with comparable unilateral headache from frontal sinusitis . - pubmed
Effects of N - acetylcysteine on myoglobinuric - acute renal failure in rats . - pubmed
This study was designed to determine the protective influence of N - acetylcysteine ( NAC ) , a hydroxyl radical scavenger , and treatment in an experimental model of myoglobinuric - ARF induced by intramuscular injection of hypertonic glycerol in rats . - pubmed
The rats were randomly distributed into five groups : Group 0 ( n = 10 ) , was assigned to receive 2mL saline ( 0,9 % ) intraperitoneally ( ip ) ; Group 1 ( n = 10 ) , NAC ip in a dose of 0 mg/100 g of body weight 30 min before the intramuscular ( i m ) injection of 50 % glycerol ( 10 mg / kg ) ; Group 2 ( n = 10 ) , received saline 0,9 % ip in a equivalent volume of NAC in Group I before the i m injection of glycerol ; Group 3 ( n = 10 ) , received NAC ip in a dose of 10 mg/100 g after i m injection of glycerol ; Group 4 ( n = 10 ) , saline 0,9 % ip in a equivalent volume of NAC of the Group 3 after i m administration of glycerol . - pubmed
The results of this study suggests that ip administration of NAC in rats before or after glycerol injection do not confer protection against impairment of renal function under these conditions in this model of myoglobinuric - ARF . - pubmed
This increase coupled with the harsh side effects of some of the cancer chemotherapies have led to the search for more natural biological products , especially those derived from plant products , currently known as herbal medicine . - pubmed
The objective of this study was to evaluate the effect(s ) of a novel water - soluble leaf extract of Vernonia amygdalina ( VA ) on human breast cancer cell DNA synthesis . - pubmed
CASE : A 28 - year - old woman was managed with total parenteral nutrition from 28 weeks ' gestation because of continuous vomiting due to esophageal hiatal hernia . - pubmed
In specific pathologic circumstances , the death program may be activated by various environmental factors such as exposure to toxic substances or bacteria or deprivation of nutrients . - pubmed
Tinea capitis due to Trichophyton tonsurans ; incidence , diagnosis and epidemiology in the San Francisco Bay Region . - pubmed
Eighty - five cases of tinea capitis due to T. - pubmed
[ I-131 - ROSE BENGAL TEST IN PATIENTS WITH CLONORCHIASIS ] . - pubmed
METHODS : Six hundred and sixty - one clinical isolates of Streptococcus pneumoniae , 936 Haemophilus influenzae and 421 Moraxella catarrhalis , collected in the winter of 1999 - 2000 by 20 laboratories in the UK and Eire from patients with presumed community - acquired lower respiratory infections , were tested by the two methods . - pubmed
OBJECTIVE : To investigate the effect of high dose mifepristone and high dose progesterone in the treatment of patients with endometrial carcinoma and to explore the possible mechanisms associating with them . - pubmed
METHODS : Thirty untreated patients diagnosed as endometrial carcinoma through dilation and curettage of the uteri were divided into 3 groups at random . - pubmed
Optimal management of patients with fulminant hepatic failure : targeting the brain . - pubmed
Tumors in the negative control animals regressed throughout the study while the tumors in the soy flour - fed animals remained basically the same size ( neither grew nor regressed ) . - pubmed
Collectively , these findings suggest that for postmenopausal women with estrogen - dependent breast cancer , the consumption of foods containing soy flour is more advisable than consuming isoflavones in more purified forms . - pubmed
The treatment of patients with acute myocardial infarction who present with the elevation of ST segment on electrocardiogram ( STEAMI ) is based on the need of re - establishing coronary blood flow through the occluded epicardial artery . - pubmed
Histomorphometry of marrow megakaryocytes in experimental uraemia in rats . - pubmed
Uraemic patients frequently demonstrate tendencies towards life - threatening bleeding . - pubmed
The aim of the study was a histomorphometric evaluation of marrow megakaryocytes in the course of experimental uraemia in rats . - pubmed
Uraemia was induced by means of right nephrectomy and a partial removal of the left kidney cortex in rats . - pubmed
Among survivors , echocardiography , hemodynamic studies , and postmortem examination indicated that the WT and KO groups of infarcted mice mounted a hypertrophic response that was augmented in KO mice . - pubmed
In this study , we analyzed the mechanism by which TZD inhibit growth of human pancreatic carcinoma cell lines in order to evaluate the potential therapeutic use of these drugs in pancreatic adenocarcinoma . - pubmed
The distribution of amphotericin B in lung tissue was studied in 18 patients with primary or secondary lung cancer who underwent thoracotomy and pulmonary resection . - pubmed
Long - term results of conservative management of adnexal torsion in children . - pubmed
METHODS : The records of 14 girls with ovarian torsion whose adnexal structures were preserved after detorsion were reviewed to evaluate the long - term results of conservative management . - pubmed
Seven patients had a benign solitary cyst as an underlying cause for adnexal torsion . - pubmed
The intervention performed by open surgery in 9 and by laparoscopy in 5 patients included detorsion , simple cyst aspiration , unroofing and/or cystectomy in 7 patients with ovarian cysts , and oophoropexy in 9 of 14 patients . - pubmed
CONCLUSIONS : Conservative management with untwisting the ovary and pexing both retained detorsed and contralateral ovaries especially in idiopathic torsions should be considered in cases of ovarian torsion in children . - pubmed
Human studies are needed to find out whether IN / OF have the potential to modulate systemic immunity in well - nourished individuals and to lower the risk of diseases such as colon cancer . - pubmed
Ten individuals with cholangiocarcinoma were transplanted between 1996 and 2003 . - pubmed
In conclusion , although early survival of patients transplanted for incidental cholangiocarcinoma appears good , intermediate- and long - term survival rates are not better than for individuals historically transplanted with known cholangiocarcinoma . - pubmed
Fluoroscopically guided balloon dilation for patients with esophageal stricture after radiation treatment . - pubmed
PURPOSE : To evaluate the safety and clinical effectiveness of fluoroscopically guided balloon dilation in patients with esophageal stricture after radiation therapy ( RT ) . - pubmed
MATERIALS AND METHODS : From April 1993 through December 2004 , fluoroscopically guided balloon dilation was performed in 15 patients with esophageal strictures secondary to previous RT . - pubmed
Two of 13 patients exhibited recurrence of dysphagia before 1 month after balloon dilation . - pubmed
Among the 11 patients in whom clinical success was achieved , seven exhibited maintained initial improvement of dysphagia until their last follow - up ( mean , 174 days ) and four exhibited recurrence of dysphagia after the first balloon dilation . - pubmed
Dysphagia recurred 2 - 128 days ( mean , 67.2 d ) after the first balloon dilation in six of the 13 patients ( 46 % ) , who underwent further balloon dilation and/or stent placement . - pubmed
Type 1 and 2 esophageal ruptures occurred after 12 dilations in nine patients ; they were treated conservatively . - pubmed
The open - bite group ( OBG ) consisted of 18 patients ( 14 girls , 4 boys ) with a mean age of 14.5 + /- 2.7 years . - pubmed
CONCLUSIONS : Compensatory tongue functions occur in patients with anterior dental open bites . - pubmed
During the 2002 - 2003 period , there were 14,023 laboratory - confirmed human cases of WNV in 45 states and 541 associated deaths . - pubmed
Larger studies of more agricultural centers are warranted to determine which environmental factors increase the risk of human infection and how these infections can be prevented . - pubmed
In five Beagle bitches hypersomatotropism was induced by administration of MPA for over 1 year . - pubmed
In conclusion , aglepristone can be used successfully to treat dogs with progestin - induced hypersomatotropism . - pubmed
OBJECTIVE : To describe possible correlations between incidence of postpartum depression and the following patient characteristics : age , breastfeeding status , tobacco use , marital status , history of depression , and method of delivery . - pubmed
To facilitate prophylactic patient education and intervention strategies , a larger study is recommended to determine risk factors for postpartum depression . - pubmed
Clinical and dynamic ( gait - related ) measures thought to be associated with pelvic retraction were investigated in patients with cerebral palsy . - pubmed
Gait laboratory data of 233 patients with cerebral palsy were studied retrospectively . - pubmed
A monkey demonstrator opened the AF , showing alternative methods to 2 groups of cage mates . - pubmed
Attention - deficit / hyperactivity disorder ( ADHD ) is the most common neurobehavioral disorder affecting school - age children . - pubmed
For school - age children , this necessitates administering medication during school hours , creating the potential for embarrassment and noncompliance . - pubmed
Its expression is down - regulated during active human Crohn ' s disease , experimental colitis in vivo , and oxidative stress in vitro . - pubmed
A 49 - year - old man , who had been diagnosed with chronic lymphocytic leukemia ( CLL ) in 2002 , had a normal karyotype in his bone marrow . - pubmed
Human papillomavirus ( HPV ) is considered to be a necessary but not sufficient cause for cervical cancer . - pubmed
The early history of plasma cell tumors in mice , 1954 - 1976 . - pubmed
Plasma cell tumors ( PCTs ) in mice became available at an exciting period in immunology when many scientists and laboratories were occupied with how to explain the genetic basis of antibody diversity as well as antibody structure itself . - pubmed
An unlimited source of PCTs in an inbred strain of mice became a useful adjunct in these efforts . - pubmed
The effect of pressure - overloading distance on left ventricular ( LV ) function in patients with congenital aortic coarctation and aortic stenosis ( AS ) was investigated . - pubmed
The World Health Organization reported that the death rate attributable to tobacco was 6.0 % worldwide and 9.2 % in China in 1990 . - pubmed
Molecular classification of patients with malignant melanoma for new therapeutic strategies . - pubmed
We can thus hope that research on the GSCs in Drosophila will benefit therapeutic approaches to human degenerative diseases . - pubmed
Human Breast Cancer and the Milk Factor . - pubmed
METHODS : We present a systematic review of reports describing the use of piracetam and its derivatives in animal models of focal ischaemia , where the outcome was measured as an infarct size or neurological score ( Der Simonian and Laird random effects meta - analysis ) . - pubmed
RESULTS : Only 2 studies , published 10 years after the first clinical trial of piracetam had been initiated , described its efficacy in animal models of stroke . - pubmed
Cytotoxicity of 1,2 - diacetylbenzene in human neuroblastoma SHSY5Y cells is mediated by oxidative stress . - pubmed
Environmental organic solvent metabolite , 1,2 - diacetylbenzene ( 1,2 - DAB ) , treated rats develop limb weakness with neuropathological damage in both the central and peripheral nervous systems . - pubmed
In this experiment , we examined the relevance of 1,2 - DAB - induced toxicity to increased oxidative stress using human dopaminergic neuroblastoma SHSY5Y cells . - pubmed
A diet low in fat and high in vegetables , fruit , and fiber following breast cancer treatment did not reduce new breast cancer events . - pubmed
These agents have been shown to reduce BC incidence in nonpregnant rats . - pubmed
Enzymatic isolation of Lacazia loboi cells from skin lesions of lobomycosis . - pubmed
Lacazia loboi is the etiologic agent of Jorge Lobo ' s disease , a cutaneous and subcutaneous mycosis endemic to Latin America tropical regions and characterized by chronic nodular or keloidal lesions which develop after traumatic events . - pubmed
, Nature 415(6871):530 - 536 , 2002 ) may improve the selection of lymph node - negative breast cancer patients for adjuvant systemic therapy . - pubmed
Optimal validation of prognostic classifiers is of great importance and we therefore wished to evaluate the prognostic value of the 70 - gene prognosis signature in a series of relatively recently diagnosed lymph node negative breast cancer patients . - pubmed
METHODS : We evaluated the 70 - gene prognosis signature in an independent representative series of patients with invasive breast cancer ( N = 123 ; & lt;55 years ; pT1 - 2N0 ; diagnosed between 1996 and 1999 ; median follow - up 5.8 years ) by classifying these patients as having a good or poor prognosis signature . - pubmed
CONCLUSION : The 70 - gene prognosis signature is also an independent prognostic factor in node - negative breast cancer patients for women diagnosed in recent years . - pubmed
The derivation of ES cells is poorly understood and varies in efficiency between different strains of mice . - pubmed
Can the principle of " LYFT " help objectively in timing renal transplantation therapy for the CKD patients ? - pubmed
We carried out a cross sectional study of 630 patients with tuberculosis and identified 100 patients with spinal involvement in the three hospitals . - pubmed
Out of the 100 patients with spinal tuberculosis , 58 % were male and 42 % were female . - pubmed
In this here , we discuss about clinical and histopathological findings in patients with spinal tuberculosis . - pubmed
INTRODUCTION : Carcinoma of the breast is the most common malignancy of women in Karachi . - pubmed
CONCLUSIONS : Given the current surgical care of patients with mutilated hand injuries , HISS determined at the time of injury can adequately predict functional outcome and return to work status . - pubmed
Laboratory investigations in animals suggest that concomitant hypoxemia hinders resuscitation attempts , and that epinephrine and vasopressin are more likely to be associated with poor outcomes than lipid . - pubmed
We report on 151 consecutive patients who had wire - free fixation of jaw fractures , and outline the value of a system of plastic anchorage points applied to individual teeth in both jaws that allows for wire - free IMF when they are linked by elastics ( Rapid IMF , Synthes , PA , USA ) . - pubmed
Using an occlusographic analysis based on angular mandibular movement in a large patient cohort , we were able to demonstrate and quantify , for the first time , the relapse . - pubmed
alata in a rat model of polycystic ovary syndrome . - pubmed
alata ( LPva)-a Malaysian herb thought to have phytoestrogenic effects - has shown promise in reducing body weight gain in ovariectomized rats . - pubmed
In this study , we investigated the effect of LPva on body composition and metabolic features in female rats treated continuously with dihydrotestosterone , starting before puberty , to induce PCOS . - pubmed
MATERIAL AND METHODS : At 9 weeks of age , the PCOS rats were randomly subdivided into two groups ; PCOS LPva and PCOS control . - pubmed
PCOS LPva rats received a daily oral dose of LPva ( 50mg / kg body weight ) , dissolved in 1 ml of deionised water , for 4 - 5 weeks . - pubmed
Avian influenza virus isolates from wild birds replicate and cause disease in a mouse model of infection . - pubmed
The direct transmission of highly pathogenic avian influenza ( HPAI ) viruses to humans in Eurasia and subsequent disease has sparked research efforts leading to better understanding of HPAI virus transmission and pathogenicity in mammals . - pubmed
These findings demonstrate the potential of wild avian influenza viruses to directly infect mice without prior adaptation and support their potential role in emergence of pandemic influenza . - pubmed
The first patient ( case 1 ) relapsed after double - unit cord blood transplantation ; there was no evidence of relapse in the second patient ( case 2 ) after allogenic peripheral blood stem cell transplantation . - pubmed
Our aim in this study was to determine the presence of complications , pseudarthrosis , non - union , and infection using combined in situ local autograft bone and freeze - dried cancellous allograft bone in patients undergoing posterior spinal fusion for the treatment of adolescent idiopathic scoliosis . - pubmed
METHODS : A combination of in situ local autograft bone and freeze - dried cancellous allograft blocks were used in 50 consecutive patients with adolescent idiopathic scoliosis treated by posterior fusion and Moss Miami pedicle screw instrumentation . - pubmed
These avian leiomyomas have been proposed as a model for similar tumours in other species . - pubmed
Effectiveness of VIA , Pap , and HPV DNA testing in a cervical cancer screening program in a peri - urban community in Andhra Pradesh , India . - pubmed
BACKGROUND : While many studies have compared the efficacy of Pap cytology , visual inspection with acetic acid ( VIA ) and human papillomavirus ( HPV ) DNA assays for the detection cervical intraepithelial neoplasia and cancer , few have evaluated the program effectiveness . - pubmed
The use of a less invasive and more user - friendly primary screening strategy ( such as self - collected swabs for HPV DNA testing ) may be required to achieve the coverage necessary for effective reduction in cervical cancer mortality . - pubmed
[ One - stage anteroposterior hemi - vertebra resection and segmental internal fixation for young children with congenital scoliosis ] . - pubmed
OBJECTIVE : to discuss the feasibility and efficacy of one - stage anteroposterior hemi - vertebra resection and segmental internal fixation for young children with congenital scoliosis . - pubmed
CONCLUSION : the procedure of one - stage anteroposterior hemi - vertebra resection and segmental internal fixation is a safe and effective treatment for scoliosis by congenital hemi - vertebra in young children . - pubmed
METHODS : We used a cross - sectional nationally representative survey of 950 primary care physicians familiar with human papillomavirus ( HPV ) testing to assess adherence to management guidelines by analyzing responses to two clinical vignettes of a 35 - year - old woman who had Pap and HPV tests results : 1 ) discordant ( normal Pap and positive HPV ) or 2 ) mildly abnormal ( atypical squamous cells of undetermined significance Pap and negative HPV ) . - pubmed
Insights into gene expression profiling of natural resistance to coccidiosis in contrasting chicken lines . - pubmed
Coccidiosis is a parasitic disease with major economic impact , one of whose main causative agents is Eimeria tenella . - pubmed
BACKGROUND : Our goal was to create a clinically relevant large animal model of pulmonary hypertension to serve as a platform allowing preclinical risk / benefit assessment of innovative therapies including artificial lung prototypes . - pubmed
RESULTS : All animals survived the study and developed pulmonary hypertension by wk 5 . - pubmed
CONCLUSIONS : We conclude that our 8 - wk model of continuous air embolization produces reliable , chronic pulmonary hypertension in sheep with sustained hemodynamic changes , significant pulmonary vascular remodeling , and right ventricle hypertrophy . - pubmed
A 92 - year - old Japanese woman consulted to our hospital because of right nasal obstruction and epistaxis . - pubmed
The tumor was reduced in size by local resection and chemotherapy ( Darthmose regimen : dacarbazine , carmustine , cisplatine , and tamoxifen ) , and the patient is now alive and free from metastasis 9 months after the first manifestation . - pubmed
METHODS : We prospectively analyzed data on all patients who underwent carotid endarterectomies for symptomatic carotid stenosis between May 12 , 2008 , and May 31 , 2011 , with records in the Swedish Vascular Registry ( Swedvasc ) . - pubmed
RESULTS : We analyzed data for 2596 patients and found that the combined mortality and stroke rate for patients treated 0 to 2 days after qualifying event was 11.5 % ( 17 of 148 ) versus 3.6 % ( 29 of 804 ) , 4.0 % ( 27 of 677 ) , and 5.4 % ( 52 of 967 ) for the groups treated at 3 to 7 days , 8 to 14 days , and 15 to 180 days , respectively . - pubmed
CONCLUSIONS : In this study of patients treated for symptomatic carotid disease , it was safe to perform surgery as early as Day 3 after a qualifying neurological event in contrast to patients treated within 0 to 2 days , which has a significantly increased perioperative risk . - pubmed
Lower physical activity is a strong predictor of cardiovascular events in elderly patients with type 2 diabetes mellitus beyond traditional risk factors : the Japanese Elderly Diabetes Intervention Trial . - pubmed
METHODS : A total of 716 specimens from gastric cancer patients who underwent curative gastrectomy between 1996 and 2003 at Zhejiang Provincial People 's Hospital were reviewed . - pubmed
RESULTS : The overall cumulative 5 - year survival rate of EGC patients was 88.92 % . - pubmed
Patients with tumors larger than 2 cm in diameters , with depth of tumor invasion to the submucosa , and with positive lymphatic or nerve involvement were also inclined to have poorer survival performances . - pubmed
Multivariate analysis identified lymphatic invasion and tumor size as independent prognosis factors related to survival in EGC patients . - pubmed
CONCLUSIONS : Careful planning is required in EGC patients at high risk of lymph node metastases . - pubmed
Infection of the subcutaneous tunnel as a major complication was found in 1 pig . - pubmed
Usefulness of diffusion tensor imaging in patients who showed sustained unexplainable clinical symptom of torticollis . - pubmed
We evaluated 10 patients with sustained torticollis and 12 age - matched control subjects . - pubmed
All patients showed no specific fibromatosis coli findings on neck sonography . - pubmed
All patients showed only torticollis symptom but no definite hemiplegic pattern on their extremities at initial evaluation . - pubmed
The results of DTT corresponded to the delayed hemiplegic symptoms , which were found in the patients at second evaluation . - pubmed
AA and AD values between patients and control group were significantly different . - pubmed
DTI may be an additional technique for the early detection of hemiplegia in patients with sustained symptoms of unexplainable postural torticollis . - pubmed
Our objective was to describe the prevalence and features of cognitive impairment in a large cohort of patients with this rare disease ( n = 57 ; mean age = 45 ) and to explore the relations between memory impairment and depression . - pubmed
Patients with mastocytosis presented high levels of cognitive impairment ( memory and/or attention ) ( n = 22 ; 38.6 % ) . - pubmed
In conclusion , immediate auditory memory and attention impairment in mastocytosis are frequent , even in young individuals , and are not consecutive to depression . - pubmed
Ehrlichia ruminantium , the etiologic agent of the economically important disease heartwater , is an obligate intracellular bacterium transmitted by ticks of the genus Amblyomma , particularly A. - pubmed
ruminantium infection in the tick vector , A. - pubmed
ruminantium DNA in 142 ( 28.4 % ) of the 500 ticks with a higher infection rate ( 47/115 ; 40.9 % ) observed in ticks from SDR and 24.7 % ( 95/385 ) of ticks collected from cattle at UFR . - pubmed
Neuropsychiatric features of a cohort of patients with systemic lupus erythematosus . - pubmed
NPSLE was identified in 22 patients . - pubmed
The series of patients was further analysed according to the presence of antiphospholipid syndrome ( APS ) . - pubmed
While there is no ambiguity in the literature about the urgency of care for patients with MSCC , the effect of timing of surgical intervention has not been investigated in detail . - pubmed
The objective of our study was to investigate whether or not the ' timing of surgery ' is an important factor in survival and neurological outcome in patients with MSCC . - pubmed
METHODS : All patients with MSCC presenting to our unit from October 2005 to March 2010 were included in this study . - pubmed
RESULTS : Patients ' age , gender , revised Tokuhashi score , level of spinal metastasis and primary tumour type were not significantly different between the three groups . - pubmed
Furthermore , earlier surgical treatment within 48 h in patients with MSCC resulted in significantly better neurological outcome . - pubmed
[ Differential characteristics of the efficacy and tolerability of second - generation antipsychotics in the treatment of psychotic disorders in children and adolescents ] . - pubmed
Over the last few years , there has been a marked increase in the prescription of second - generation antipsychotics ( SGA ) for the treatment of psychotic disorders and other psychiatric conditions in children and adolescents . - pubmed
Patients with adequate urea clearance and delivered dialysis session & gt;=240 and & lt;240 minutes were pair - matched on interdialytic weight gain ( n=1794 ) , and patients with weight gain & lt;=3 and & gt;3 kg were pair - matched on session length ( n=2114 ) ; mortality associations were estimated separately . - pubmed
A prospective randomized study was performed of 78 eyes in primary pterygium patients treated by excision . - pubmed
Primary pterygium patients were randomly assigned to ethanol group ( 38 eyes given intraoperative ethanol ) or mitomycin - c ( MMC ) group ( 40 eyes given intraoperative MMC ) . - pubmed
It suggests this regimen as an alternative for the treatment of pterygium , especially for those patients of high risk group for MMC treatment complications . - pubmed
Dynamics of milk leukocytes in response to a biological response modifier during bovine subclinical mastitis . - pubmed
The objective of this study was to evaluate the dynamics of milk leukocyte in response to intramammary infusion of a biological response modifier ( BRM ) prepared from Nocardia globerula during bovine subclinical mastitis ( SCM ) . - pubmed
SUMMARY : Diagnosis and treatment of patients with severe ocular allergy is a challenge for ophthalmologists due to the long - term corneal complications and the potential side - effects of topical corticosteroids that may induce cataract formation and glaucoma , and impair vision permanently . - pubmed
The G+C content of the genomic DNA of strain PB156(T ) was 61.7 mol% . - pubmed
The type strain is PB156(T ) ( = KCTC 32477(T ) = JCM 19433(T ) ) . - pubmed
MATERIALS AND METHODS : Two - hundred and fifty one patients admitted within 24 h of onset of stroke symptoms into the stroke unit of a tertiary care hospital were followed up for convulsive seizure(s ) within 7 days of admission and for disease outcome in 42 days . - pubmed
Coincidental metabolic syndrome increases the risk of liver fibrosis progression in patients with chronic hepatitis B -- a prospective cohort study with paired transient elastography examinations . - pubmed
METHODS : A total of 1466 CHB patients underwent liver stiffness measurement ( LSM ) by transient elastography in 2006 - 2008 ; 663 patients remained treatment - naive and had second LSM in 2010 - 2012 . - pubmed
Metabolic syndrome was diagnosed in 80 ( 12 % ) and 142 ( 21 % ) patients at baseline and follow - up visit , respectively ; 84 ( 13 % ) and 22 ( 3 % ) patients had coincidental and resolved metabolic syndrome respectively . - pubmed
After an interval of 44 + - 7 months , 107 ( 16 % ) patients developed liver fibrosis progression . - pubmed
CONCLUSION : Coincidental metabolic syndrome increases the risk of liver fibrosis progression in patients with chronic hepatitis B infection , independent of viral load and hepatitis activity . - pubmed
Budesonide loaded nanoparticles with pH - sensitive coating for improved mucosal targeting in mouse models of inflammatory bowel diseases . - pubmed
The efficacy of both coated and plain nanoparticle formulations was assessed in different acute and chronic colitis mouse models , also in comparison to an aqueous solution of the drug . - pubmed
Prevalence of the rs12979860 CC genotype among genotype 1 HCV infected patients of Asian ethnicity was 69.48 % ( 95 % CI : 65.20 - 73.77 ) , which was significantly higher than its prevalence [ 33.27 % ( 95 % CI : 28.88 - 37.67 ) ] in the Caucasian genotype 1 HCV infected patients . - pubmed
Small cell carcinoma of the prostate ( PSCC ) is a highly aggressive malignancy that often develops in patients previously treated with hormonal therapy for metastatic prostatic acinar adenocarcinoma . - pubmed
These findings suggest a key role for blood monocytes in the rapid onset of fever in animals and humans exposed to bacterial products and some novel adjuvants . - pubmed
Death and transfiguration in static Staphylococcus epidermidis cultures . - pubmed
However , when several Staphylococcus epidermidis strains were cultivated in static liquid cultures , macroscopic aggregates were seen floating within the broth and also sedimented at the test tube bottom . - pubmed
These observations indicate that some strains of Staphylococcus epidermidis are able to build highly sophisticated structures , in which a subpopulation undergoes cell lysis , presumably to provide continued access to nutrients in a nutrient - limited environment , whilst maintaining structural integrity . - pubmed
Two novel toxin variants revealed by whole - genome sequencing of 175 Clostridium botulinum type E strains . - pubmed
We sequenced 175 Clostridium botulinum type E strains isolated from food , clinical , and environmental sources from northern Canada and analyzed their botulinum neurotoxin ( bont ) coding sequences ( CDSs ) . - pubmed
The present study aims to characterize the chemical nature of avocado constituents with inhibitory effects on platelet aggregation . - pubmed
From these results , avocado may be referred to as a functional food containing acetogenin compounds that inhibit platelet aggregation with a potential preventive effect on thrombus formation , such as those that occur in ischaemic diseases . - pubmed
Establishment of a murine graft - versus - myeloma model using allogeneic stem cell transplantation . - pubmed
We observed a GvM effect in 94 % of the allogeneic transplanted mice , as the luciferase signal completely disappeared after transplantation , whereas all the autologous transplanted mice showed myeloma progression . - pubmed
In addition , the treated mice also displayed chronic GvHD symptoms . - pubmed
CONCLUSIONS : We successfully established an immunocompetent murine model of graft - versus - myeloma . - pubmed
The protective effect of caffeic acid on global cerebral ischemia - reperfusion injury in rats . - pubmed
The aim of this study was to investigate the effect of caffeic acid on global cerebral ischemia - reperfusion injury in rats . - pubmed
Caffeic acid markedly reduced the escape latency , relieved hippocampal neurons injury and increased neuron count compared with those of I / R non - treated rat . - pubmed
The results of the study suggest that caffeic acid has a significant protective effect on global cerebral ischemia - reperfusion injury in rats . - pubmed
In cattle , this neoplasm is very rare and to date has only been described three times . - pubmed
This report provides the first sonographic images of bovine testicular yolk sac tumor as well as the first information about hormone levels in calves with this neoplasm . - pubmed
We report a case of a patient with angioimmunoblastic T - cell lymphoma presenting initially with pruritus and saggy skin , which later progressed into erythroderma despite chemotherapy ; the disease eventually resolved with autologous stem cell transplant . - pubmed
We report a 64 - year - old woman morphologically diagnosed with chronic myelogenous leukemia in the chronic phase . - pubmed
AREAS COVERED : This review covers the preclinical and clinical studies of erlotonib as it relates to its use in the treatment of NSCLC patients with BM . - pubmed
Obesity - linked type 2 diabetes is one of the paramount causes of morbidity and mortality worldwide , posing a major threat on human health , productivity , and quality of life . - pubmed
It has been suggested that one in five riders will be injured due to a fall from a horse , resulting in severe head or torso injuries . - pubmed
The article concludes with a practical application of WHS to prevent horse - related injury by discussing effective evidence - based guidelines and regulatory monitoring for equestrian sectors . - pubmed
It suggests that the WHS framework has significant potential not only to reduce the occurrence and likelihood of horse - related human accident and injury , but to enable systematic accident analysis and investigation of horse - related adverse events . - pubmed
Cystic Fibrosis Isolates of Pseudomonas aeruginosa Retain Iron - Regulated Antimicrobial Activity against Staphylococcus aureus through the Action of Multiple Alkylquinolones . - pubmed
Early infection of the CF lung with Staphylococcus aureus is common , while Pseudomonas aeruginosa becomes dominant as disease progresses . - pubmed
Compensatory increases in HHQ were also observed in PQS - deficient CF isolates , which also retained the ability to mediate iron - regulated antimicrobial activity against S. - pubmed
CONCLUSIONS : A vascular risk assessment and neurological examination are adequate for risk stratification of ischemia in the dizzy patient and should remain the standard evaluation . - pubmed
Our study presents a case report of a patient with a retroperitoneal leiomyosarcoma that was radically ( R0 ) removed . - pubmed
Articular cartilage degeneration causes pain and reduces the mobility of millions of people annually . - pubmed
RESULTS : Twenty - one of 2423 patients who underwent ERCP had a perforation ( 0.9 % ) . - pubmed
RATIONALE : Ascariasis is an endemic parasitic disease caused by Ascaris lumbricoides , which severely burdens the healthcare system as well as harms the personal life quality , especially among less developed regions . - pubmed
Concurrent administration of thyroxine and donepezil induces plastic changes in the prefrontal cortex of adult hypothyroid rats . - pubmed
Adding 0.05 % propylthiouracil to rats ' drinking water induced a hypothyroid rat model . - pubmed
CONTEXT : Partner services are a broad array of services that should be offered to persons with human immunodeficiency virus ( HIV ) and that are based on a process through which HIV - infected persons are interviewed to elicit information about their sex and needle - sharing partners . - pubmed
Human immunodeficiency virus testing of partners can result in a high yield of newly diagnosed HIV positivity , but despite this yield and the benefits of partners knowing their exposures and HIV status , partner services are often not conducted . - pubmed
METHODS : From January 2008 to November 2015 , two hundred and forty - five consecutive patients with an average age of 36.2 + - 10.9 years ( range , 17 - 66 years ) satisfying the Modified New York Criteria for AS from a single institution were enrolled . - pubmed
Coronary artery bypass grafting in patients with severe chronic kidney disease : a propensity score - weighted analysis on the impact of on - pump versus off - pump strategies . - pubmed
OBJECTIVES : The optimal surgical strategy regarding the use of cardiopulmonary bypass during coronary artery bypass grafting in patients with severe chronic kidney disease remains controversial . - pubmed
METHODS : Between 1997 and 2015 , we identified 321 consecutive patients with severe chronic kidney disease ( Stage 4 or 5 ) based on the National Kidney Foundation Classification ( estimated glomerular filtration rate & lt;30 ml / min/1.73 m2 ) . - pubmed
CONCLUSIONS : The on - pump strategy for patients with severe chronic kidney disease was associated with a significantly higher risk of mortality and morbidities , which is particularly attributable to a greater risk of cardiopulmonary bypass use in the early postoperative period . - pubmed
CDDO - EA was evaluated in vivo as a monotherapy as well as adjunctive therapy with parenteral artesunate in the Plasmodium berghei strain ANKA experimental cerebral malaria ( ECM ) model . - pubmed
Microfracture augmented by autologous bone marrow concentrate ( BMC ) was previously shown to yield structurally superior cartilage repairs in an equine model compared with microfracture alone . - pubmed
CONCLUSIONS : When BMC was applied directly to critical - sized , full - thickness chondral defects in an equine model , the cartilage repair results were similar to those of microfracture . - pubmed
Using the chronic kidney disease guidelines to evaluate the renal safety of tenofovir disoproxil fumarate in hepatitis B patients . - pubmed
BACKGROUND : Renal dysfunction remains an issue in tenofovir disoproxil fumarate ( TDF ) for chronic hepatitis B ( CHB ) patients . - pubmed
METHODS : We retrospectively recruited CHB patients who received either TDF or entecavir ( ETV ) monotherapy from January 2008 to August 2015 . - pubmed
After excluding confounding conditions , 253 patients who received TDF were randomly matched 1:2 with 506 patients who received ETV through the propensity scores , which consisted of age , gender , cirrhosis , chronic kidney disease ( CKD ) and estimated glomerular filtration rate ( eGFR ) . - pubmed
Methods : A prospective , observational study was carried out on 25 wrists of 20 consecutive patients with carpal tunnel syndrome , confirmed by the American Association of Neuromuscular and Electrodiagnostic Medicine criteria , which includes clinical history , symptoms , and evidence of slowing of distal median nerve conduction . - pubmed
[ Prognostic significance of the total ischemic time in patients with ST - elevation myocardial infarction ] . - pubmed
METHOD : From 1 January 2014 all patients with myocardial infarction were recorded by law in an on - line database of the Hungarian Myocardial Infarction Registry . - pubmed
Between 1 January 2014 and 31 March 2016 , 27 157 patients with 28 408 myocardial infarction events were recorded . - pubmed
To investigate TIT , 7146 STEMI patients were selected who were treated with percutaneous coronary intervention ( PCI ) within 24 hours of the beginning of the complaint and all of its components were known . - pubmed
The TIT is an independent prognostic factor , so reducing this time can improve the long - term prognosis of patients with ST - elevation myocardial infarction . - pubmed
Sulthiame add - on therapy in children with Lennox - Gastaut syndrome : A study of 44 patients . - pubmed
PURPOSE : The aim of this study was to evaluate efficacy and tolerability of sulthiame as an add - on treatment in 44 patients with Lennox - Gastaut syndrome ( LGS ) refractory to other antiepileptic drugs and/or non - pharmacological treatment . - pubmed
METHODS : Patients were selected according to the following criteria : ( 1 ) age 4 years or older , ( 2 ) a diagnosis of LGS refractory to at least four previous antiepileptic drugs , alone or in combination . - pubmed
RESULTS : Twenty - seven of 44 patients ( 61 % ) who received sulthiame as add - on therapy had a greater than 50 % seizure decrease after a mean follow - up period of 20 months . - pubmed
Complete seizure freedom was achieved in one patient ( 2 % ) . - pubmed
Four patients ( 9 % ) had a 25 - 50 % seizure decrease , while seizure frequency remained unchanged in 12 ( 25 % ) , and was increased in one ( 2 % ) . - pubmed
Hyperpnoea and dyspnoea were observed in four patients , and nausea , drowsiness , and headache were seen in one patient each ; however , these manifestations were transient and discontinuation of sulthiame was not necessary . - pubmed
Two other patients had decreased appetite , skin rash , and irritability . - pubmed
CONCLUSION : Sulthiame as an adjunctive therapy achieved a more than 50 % seizure reduction in 27 of 44 patients with LGS with only mild or moderate adverse effects . - pubmed
Anti - atherosclerosis of oligomeric proanthocyanidins from Rhodiola rosea on rat model via hypolipemic , antioxidant , anti - inflammatory activities together with regulation of endothelial function . - pubmed
Human papillomavirus testing may detect cervical precancer better than Papanicolaou testing . - pubmed
In - hospital mortality was high in syncope patients with pulmonary embolism ( PE , 13.0 % ) , pneumonia ( 12.8 % ) , myocardial infarction ( MI , 9.7 % ) and stroke ( 8.5 % ) . - pubmed
Integrated miRNA and mRNA expression analysis uncovers drug targets in laryngeal squamous cell carcinoma patients . - pubmed
Little is known about norovirus infections in most non - human hosts , but the close genetic relatedness between some animal and human noroviruses coupled with lack of understanding where newly appearing human norovirus genotypes and variants are emerging from has led to the hypothesis that norovirus may not be host restricted and might be able to jump the species barrier . - pubmed
There is no cure for SLE , but current standard pharmacotherapies can improve disease prognosis in most patients . - pubmed
All adult patients identified in the Nanjing database with an SLE Disease Activity Index ( SLEDAI ) score & gt;= 8 at baseline that had undergone MSC transplant and who had at least 1 year of follow - up after one or two successive intravenous injections of allogeneic BM-/UC - MSCs ( 1 million / kg ) were analyzed . - pubmed
Women with adnexal lesions and/or persistently elevated risk were clinically assessed and underwent surgery or follow - up for a median of 10.9 years . - pubmed
Area under the curve and sensitivity for diagnosing ovarian cancer of multiple penalized logistic regression models incorporating logCA125 , log human epididymis 4 , age , and simple ultrasound features of the adnexal mass were compared . - pubmed
RESULTS : Of 1590 ( 158 multimodal , 1432 ultrasound ) women with adnexal masses , 78 were diagnosed with ovarian cancer ( 48 invasive epithelial ovarian , 14 type I , 34 type II ; 24 borderline epithelial ; 6 nonepithelial ) within 1 year of scan . - pubmed
Isoquinolinamine FX-9 Exhibits Anti - Mitotic Activity in Human and Canine Prostate Carcinoma Cell Lines . - pubmed
Current therapies are insufficient for metastatic prostate cancer ( PCa ) in men and dogs . - pubmed
As human castrate - resistant PCa shares several characteristics with the canine disease , comparative evaluation of novel therapeutic agents is of considerable value for both species . - pubmed
In this study , FX-9 's mediated effects were characterized on two human ( PC-3 , LNCaP ) and two canine ( CT1258 , 0846 ) PCa cell lines , as well as benign solid tissue cells . - pubmed
BACKGROUND : Atherosclerosis is a chronic inflammatory condition that affects different arteries in the human body and often leads to severe neurological complications , such as stroke and its sequelae . - pubmed
Members of the let-7 family of miRNAs are well - known with their tumor suppressor properties as they are expressed at low levels in several types of human malignancies . - pubmed
We found that both let-7b and let-7c were significantly altered in breast cancer and associated with the clinicopathological findings of patients . - pubmed
Effect of disinfectant residuals on infection risks from Legionella pneumophila released by biofilms grown under simulated premise plumbing conditions . - pubmed
pneumophila released from biofilms reported previously were integrated into a Monte Carlo framework to estimate the infection risk of biofilm - derived L. - pubmed
Stagnation caused by water use patterns and water - saving devices in the premise plumbing can lead to increased infection risk by biofilm - derived L. - pubmed
Traumatic spinal cord injury ( SCI ) results in persistent functional deficits due to the lack of axon regeneration within the mammalian CNS . - pubmed
Unlike mammals , the sea lamprey , Petromyzon marinus , robustly recovers locomotion after complete spinal cord transection ( TX ) . - pubmed
Brain metastasis is a major cause of death in breast cancer patients . - pubmed
All the patients presented with ecchymosis and intramuscular hematoma . - pubmed
To date , silibinin ( SBN ) is a one the most studied hepatoprotective plant - derived agents for prevention / alleviation of drug - induced liver injury . - pubmed
In vivo analysis of hepatoprotective effects of PLGA / SBN nanoparticles was carried out on melanoma tumor - bearing syngeneic mouse model treated with the antineoplastic drug dacarbazine ( DTIC ) , which often causes severe hepatotoxicity including development of veno - occlusive disease . - pubmed
PURPOSE : Time course of the recovery of otolithic dis - function caused by superior vestibular neuritis has been examined in fifteen patients . - pubmed
OBJECTIVE : To assess the impact of fondaparinux on venous thromboembolism ( VTE ) following elective lumbar spine surgery in high - risk patients . - pubmed
Increased wound drainage was seen in 18.5 % of patients administered fondaparinux , compared with 25.5 % of untreated patients ( P = .15 ) . - pubmed
CONCLUSIONS : Patients receiving fondaparinux had lower rates of symptomatic DVT and PE and a favorable complication profile when compared with matched controls . - pubmed
The retrospective nature of this work limits the safety and efficacy claims that can be made about the use of fondaparinux to prevent VTE in elective lumbar spine surgery patients . - pubmed
Areca palm yellow leaf ( AYL ) disease caused by the 16SrI group phytoplasma is a serious threat to the development of the Areca palm industry in China . - pubmed
To gain insights into the association of progressive accumulation of GlcCer and the Parkinson ' s disease phenotypes , we generated dopaminergic ( DA ) neurons from induced pluripotent stem cells ( iPSCs ) derived from a GD1 patient and a healthy donor control , and measured GlcCer accumulation by liquid chromatography - mass spectrometry . - pubmed
These results suggest that synthetic mRNA - based method accelerates the analyses of the pathological mechanisms of Parkinson ' s disease in GD1 patients and possibly facilitates drug discovery processes . - pubmed
Conclusion : Use of ACEI or ARBs prior to hospitalization was not associated with adverse outcomes in COVID-19 and the therapeutic benefits of continuing ACEI or ARB in hospitalized patients with COVID-19 was not offset by adverse outcomes . - pubmed
, SARS - CoV ) and MERS , in exhibiting severe flu - like symptoms and acute respiratory distress . - pubmed
Even at the molecular level , many parallels have been identified between SARS and COVID-19 so much so that the COVID-19 virus has been named SARS - CoV-2 . - pubmed
Importantly , the identification of similarities in how SARS - CoV and SARS - CoV-2 access the host , replicate , and trigger life - threatening pathological conditions have revealed opportunities to repurpose drugs that were proven to be effective against SARS . - pubmed
Parenteral administration of gold thioglucose to mice produces an area or necrosis in the ventromedial portion of the hypothalamus . - pubmed
Neisseria catarrhalis empyema in an immunodeficient host . - pubmed
Meningococcus strains -- standard and those isolated from the cerebrospinal fluid of patients suffering from the cerebrospinal meningitis were grown on fluid and solid protein - free nutrient media . - pubmed
[ Use of lignocaine phonophoresis and electrophoresis in the treatment of patients with ankylosing spondylitis ] . - pubmed
Experiments with several patients suffering from stress incontinence have shown that indirect stimulation of the levator ani with a vaginal stimulator and especially of the anal sphincter with an anal stimulator affects the urethral sphincter in the same way as direct stimulation . - pubmed
The importance of nursing / social work liaisons in coordinating treatment and follow - up of head and neck cancer patients is discussed . - pubmed
Phage susceptibility , enterotoxigenicity and antibiograms of Staphylococcus aureus strains isolated from human wounds and diarrhoea . - pubmed
The phage types , enterotoxigenicity and antibiograms of Staphylococcus aureus strains isolated from human diarrhoea and skin wounds in Nigeria were determined . - pubmed
Phage 119 , a bovine phage , lysed all 19 strains of diarrhoeal origin sensitive to group M phages but all wound strains were resistant . - pubmed
aureus strains of bovine origin associated with human diarrhoea in Nigeria . - pubmed
Ultrastructure of hepatocellular neoplasms in aflatoxin B1 ( AFB1)-initiated rainbow trout ( Oncorhynchus mykiss ) . - pubmed
The fine structure of hepatocellular neoplasms from aflatoxin B1 ( AFB1)-initiated rainbow trout was studied by transmission electron microscopy . - pubmed
Of the 19 patients with mammary Paget ' s disease , specimens of underlying breast tissue were available from 14 ; all contained a concurrent ductal adenocarcinoma . - pubmed
Of the 13 patients with vulvar Paget ' s disease , 2 had superficial stromal invasion , and 3 had underlying , deeply invasive adenocarcinomas . - pubmed
Hepatocellular carcinoma mainly affects patients with cirrhosis or with various degrees of fibrosis . - pubmed
From 1979 to 1990 , among 87 patients who underwent hepatic resection for non fibrolamellar hepatocellular carcinoma , 12 ( 14 % ) had a non fibrolamellar hepatocellular carcinoma developed in a normal liver . - pubmed
In 7 patients ( 58 % ) hepatocellular carcinoma was associated with clinical manifestations . - pubmed
Intra or extrahepatic recurrence was recognized in 8 ( 67 % ) , 2 patients were alive respectively 28 and 16 months after treatment of their intrahepatic recurrence ( resection in one and intraarterial embolisation in one ) . - pubmed
Ninety - four patients admitted to a Coronary Care Unit ( CCU ) complaining of chest pain with the preliminary diagnosis suspect MI were included in the study . - pubmed
The results correlate well with the carcinogenic activity of these oils in experimental animals , helping to substantiate the conclusion that petrol engine oils ( but not diesel engine oils ) may present a carcinogenic risk to man if appropriate measures to minimise skin contact are not observed . - pubmed
35 tumors of brain , spinal cord and cranial and peripheral nerves were induced with ENU ( ethyl - nitrosourea ) in the offspring of treated BD - IX pregnant rats . - pubmed
36 tumors--35 of the nervous system , one nephroblastoma -- were observed in 14 rats . - pubmed
With these results , the number of experimental nervous system tumors of the own collection induced in BD - IX rats and classified next to the rules of human neurooncology , amounts to 2,216 . - pubmed
Recovery of contractility and pHi during respiratory acidosis in ferret hearts : role of Na(+)-H+ exchange . - pubmed
[ Treatment of anemia with animal blood preparation " Livex " in children with pyelonephritis ] . - pubmed
The results are presented of anaemia treatment during pyelonephritis in 20 children with the preparation obtained from animal blood livex . - pubmed
In acute toxicity tests with BALB / c mice no deaths were recorded even at a dose level of 2 g / kg body wt / day . - pubmed
To our knowledge , this is the first documented case of isolated pulmonary phaeohyphomycosis due to E dermatitidis , and it was successfully treated with amphotericin B and 5 - fluocytosine . - pubmed
The propofol patients were significantly better relaxed and had a higher incidence of hypotension during the procedure . - pubmed
The methohexitone patients had higher pulse rates and a higher frequency of hiccups during the procedure . - pubmed
Morphohistometric investigations of placentas of diabetic patients in correlation to the metabolic adjustment of the disease . - pubmed
In addition , the potential irritative action of the same preparation of IDU was investigated in a more suitable animal model . - pubmed
Experiments on guinea pigs showed slight transient erythematous responses in three animals of the test group following first challenge , and in one animal of the test group and one of the control group , following the second challenge . - pubmed
The surgical operations including 5 cholecystectomies , gastrectomy , and graft implantation for abdominal aortic aneurysm were performed on 7 patients 2 to 98 months after valve replacement . - pubmed
There were two episodes of hemorrhage required blood transfusion , observed in patients receiving heparin therapy , but there was no thromboembolism . - pubmed
Use of this technique has allowed us to ascertain that isolated rib lesions in two patients with extra - osseous malignancies were not due to metastatic disease . - pubmed
Both lpr / lpr and gld / gld mice and an AILD patient with lymphadenopathy and high myb RNA in peripheral blood cells were treated with cyclophosphamide ( CY ) . - pubmed
A single large dose of CY led to marked regression of the lymphadenopathy of gld / gld mice and long - term amelioration of their autoimmune syndrome . - pubmed
In contrast , similar treatment of lpr / lpr mice failed to alter either the lymphadenopathy or the disease process . - pubmed
The AILD patient reacted much like the gld / gld mice in that myb RNA levels in the peripheral blood , and bone marrow returned to normal after only three doses of CY . - pubmed
The lymphadenopathy and high levels of LN myb mRNA of the lpr / lpr mice could be normalized ; this occurred only after long - term treatment with CY . - pubmed
Zinc and wound healing in normal and chronically ill rats . - pubmed
Exclusion , superinfection immunity and abortive recombinants in I+ X I+ bacterial crosses . - pubmed
Uterine pouch of the rabbit as an incubator for human tumor . - pubmed
Diuretic responses to water - load in four strains of mice . - pubmed
The kinetics of excretion of water , sodium and potassium following a stomach load of water , with and without an initial injection of vasopressin , are described in each of four strains of mice : RAP , CBA / FaCam , Peru and A / Cam.2 . - pubmed
The strains of mice differed significantly in diuretic lag , maximum rate of diuresis , and 3 hr excretion of water and electrolytes.5 . - pubmed
32:276 - 292 , 1979 ) revealed a remarkably high rate of spontaneous deletion in viral DNA during lytic infection of cultured murine cells with minute virus of mice ( MVM ) , an autonomous parvovirus . - pubmed
[ Diagnosis , prognosis and therapeutic results in urothelial dysplasia in patients with bladder cancer ] . - pubmed
Herpes zoster in patients with systemic lupus erythematosus . - pubmed
Acute and chronic complications of laser angioplasty : vascular wall damage and formation of aneurysms in the atherosclerotic rabbit . - pubmed
Acute and chronic vascular responses to laser exposure in atherosclerotic rabbits were studied . - pubmed
In 7 rabbits fed an atherogenic diet for 3 to 5 months before the study to induce aortic atherosclerosis , a flexible quartz fiber , 400 micron core diameter , attached to an argon ion laser was passed anterogradely or retrogradely to the atherosclerotic ascending aorta . - pubmed
In 2 rabbits studied acutely , the argon laser produced a vaporized crater within the atherosclerotic plaque at the endothelial surface ; however , in 1 there was also vascular damage extending deep into the medial layer . - pubmed
In addition , aortic aneurysm with muscular wall damage occurred in 2 of the 4 animals studied chronically . - pubmed
This study suggests caution in the clinical use of intensive phototherapy to cardiovascular lesions and stresses the need for further understanding of laser vascular consequences before application of laser angioplasty in patients . - pubmed
Fatal Shigella dysentery complicated by toxic megacolon and bone marrow aplasia in a patient with chronic granulocytic leukemia in remission . - pubmed
A patient with Philadelphia positive chronic granulocytic leukemia in clinical remission is described , who developed Shigella dysentery complicated by fatal toxic megacolon , pancytopenia and bone marrow aplasia . - pubmed
In the present study , the reproducibility of this finding was examined by application of a similar method in seven normal comparison subjects and seven neuroleptic - naive schizophrenic patients examined by PET before and after administration of haloperidol , 7.5 mg . - pubmed
Long - term follow - up study of " epileptic type " moyamoya disease in children . - pubmed
Twenty - three patients with epileptic type moyamoya disease are reviewed among 200 moyamoya disease patients . - pubmed
Nineteen patients improved and suffered no seizure without receiving antiepileptic drugs , but four patients developed true epilepsy and three of these suffered cerebral infarction . - pubmed
Treatment of thalassemia major requires consideration of the available therapeutic options for each patient , and the risk / benefit ratio of a supportive versus curative approach . - pubmed
The influence of some fermentation parameters on vitamin B12 formation by strains of Citrobacter freundii and Klebsiella pneumoniae isolated from Indonesian tempeh samples during tempeh fermentation was investigated . - pubmed
This result supports the suggested use of these two strains to form vitamin B12 during tempeh fermentation in Indonesia . - pubmed
Quinolones in treatment of human brucellosis : comparative trial of ofloxacin - rifampin versus doxycycline - rifampin . - pubmed
Gastric discomfort was the major side effect observed in 13 patients ( 43.3 % ) who received doxycycline plus rifampin , whereas only 2 patients ( 6.5 % ) treated with ofloxacin plus rifampin complained of gastric irritation . - pubmed
Absence epilepsies , which are easily recognized by the provocation of an episode during hyperventilation and by the typical features of the EEG , can be overdiagnosed , especially in the child who daydreams in class and has scattered , asymptomatic , epileptogenic EEG changes . - pubmed
As in adults , complex partial seizures in children can be difficult to distinguish from certain behaviors . - pubmed
Some recurrent nonepileptic events seen in children can be mistaken for seizures , including shuddering attacks , paroxysmal vertigo , breath - holding spells , cardiogenic syncope , night terrors , and movement disorders , such as paroxysmal kinesigenic choreoathetosis . - pubmed
[ Characteristics of left ventricular systolic and diastolic functions in patients with essential hypertension ] . - pubmed
The aim of this study was to assess the degree of residents ' concern about acquiring hepatitis B virus ( HBV ) and human immunodeficiency virus ( HIV ) infection from their patients at the University College Hospital , Ibadan , Nigeria . - pubmed
In general , the results demonstrate a major degree of concern about acquiring HBV and HIV infections among resident doctors . - pubmed
Erection failure as a sequela to obstructive urolithiasis in a male goat . - pubmed
Aborted sudden death as the presenting manifestation of hypertrophic cardiomyopathy in a 14 - year - old child is reported . - pubmed
Left ventricular hypertrophy may develop during childhood in patients with hypertrophic cardiomyopathy . - pubmed
RESULTS : A polyp was diagnosed in 12 patients , a submucous myoma in one patient , a proliferated endometrium in five patients and a placental polyp in one patient . - pubmed
A sonographic irregular structure was diagnosed in one patient which turned out to be coagula on hysteroscopy and histology . - pubmed
Patients with multiple system atrophy ( MSA ) often have cold , dusky , violaceous hands , with poor circulatory return after blanching by pressure . - pubmed
Baseline skin temperature in the MSA group was significantly lower than in both the PD and control groups , and four of the nine MSA patients were colder at baseline than the coldest control value . - pubmed
BACKGROUND AND OBJECTIVE : Antiplatelet agents are often included in plasma exchange - based regimens for thrombotic thrombocytopenic purpura ( TTP ) patients ; however , the opportuneness of their use in TTP is still controversial . - pubmed
METHODS : Seventy - two TTP patients were randomized to receive plasma exchange and steroids with ( group B ) or without ( group A ) aspirin and dipyridamole . - pubmed
RESULTS : Regarding the treatment of acute phase TTP , similar overall response rates were observed in the two groups ( 91.4 % in group B vs. 75.6 % in group A ) , but lower mortality rates were observed at 15 days in the patients treated with antiplatelet agents ; as a matter of fact , 5 patients from arm A died in the first 15 days ( 13.5 % ) versus only one in arm B ( 2.8 % ) . - pubmed
These figures , while not statistically significant , seem to suggest that antiplatelet agents might be useful in preventing deaths in acute TTP ; moreover , bleeding did not worsen in antiplatelet agent - treated patients . - pubmed
As for the role of maintenance treatment , our results support the efficacy and safety of one - year ticlopidine therapy since the current relapse rate is significantly higher in non - treated patients ; as a matter of fact , 6 patients ( 21.4 % ) in the non - ticlopidine group and only 2 ( 6.25 % ) in the ticlopidine group relapsed ( P = .0182 in favor of maintenance treatment ) . - pubmed
INTERPRETATION AND CONCLUSIONS : Our results suggest the usefulness of antiplatelet agents in the treatment of acute phase TTP patients . - pubmed
[ Treatment of cerebral metastasis in patients with testicular germ cell tumors ] . - pubmed
Coronary angioscopy , intravascular ultrasound , and angiography were compared in 20 patients regarding their sensitivity and specificity in the detection of thrombus . - pubmed
PATIENTS AND METHODS : Fifty - seven patients with 58 cases of breast cancer were evaluated preoperatively with MRI using a technique called the triple - acquisition rapid gradient echo technique to maximize anatomic detail . - pubmed
Between January 1995 and January 1998 , 21 patients with oesophageal compression due to malignant mediastinal tumours underwent oesophageal stent placement for palliation of dysphagia . - pubmed
Of the 17 patients , 16 reported an improvement in dysphagia . - pubmed
Early complications ( within 48 h ) in the form of mild to moderate retrosternal chest pain occurred in 5 patients . - pubmed
In 2 patients the stent was overgrown by tumour and in one of these an additional stent was placed . - pubmed
In 1 patient incomplete closure of a tracheo - oesophageal fistula was observed . - pubmed
Dystonia is often associated with myoclonus , rigidity , apraxia , alien hand phenomenon , and sensory cortical signs in the affected limb , and there are no significant differences between the occurrence of these or other features , between patients with or without dystonia . - pubmed
Magnetic resonance imaging findings in 13 patients with acute transverse myelitis are reviewed . - pubmed
Activation of serotonergic pathways from the midbrain raphe system to the subfornical organ by hemorrhage in the rat . - pubmed
Mutans streptococci and Lactobacillus as risk factors for dental caries in 12 - year - old children . - pubmed
Spinal cord blood flow changes following systemic hypothermia and spinal cord compression injury : an experimental study in the rat using Laser - Doppler flowmetry . - pubmed
METHODS : Twenty - four rats were randomized either to thoracic laminectomy only ( Th VII - IX ) or to 35 g spinal cord compression trauma . - pubmed
The animals were further randomized to either constant normothermia ( 38 degrees C ) or to a systemic cooling procedure , ie reduction of the esophageal temperature from 38 to 30 degrees C. SCBF was recorded 5 mm caudal to the injury zone using Laser - Doppler flowmetry which allows a non - invasive continuous recording of local changes in the blood flow . - pubmed
We show the concrete case of a 66 years woman , who has a due to toxic multinodular goiter hyperthyroidism with jaundice and serious pulmonary hypertension associated , unexplainable by further causes , both regressing with normalisation of thyroid function with no evidence of associated autoimmune pathology . - pubmed
The disease of Epstein - Barr virus ( EBV ) -associated recurrent necrotic papulovesicles is a distinct clinicopathologic entity different from classic hydroa vacciniforme ( HV ) . - pubmed
OBJECTIVE : Subsequent to an outbreak of invasive Paecilomyces lilacinus mycosis among patients of an isolation ward , probably caused by a contaminated skin care product , the microbiological quality of different skin care products from the market was investigated . - pubmed
CPA can be the natural ending of a normal and long life ; however , when CPA is the result of a reversible problem in an animal that has a treatable medical condition , rapid recognition and treatment may make the difference between a happy ending and premature death . - pubmed
The term cardiopulmonary cerebral resuscitation originated in the early 1960s in recognition of the severe central nervous system complications of prolonged cardiac arrest in human beings . - pubmed
Although neurologic complications of CPA may not be as noticeable in companion animals , newer brain - sparing strategies that recognize the consequences of reperfusion injury and the inflammatory cascade may some day offer improved survival . - pubmed
METHODS : Thirteen adult dogs were randomly assigned to one of two study groups 6 hours after the induction of severe intra - abdominal infection . - pubmed
The wound complication rate was 3.5 % for axillae and 7 % for patients . - pubmed
PATIENTS AND METHODS : Eighty - three patients underwent endoscopic sinus surgery for refractory chronic sinusitis . - pubmed
CONCLUSIONS : Duration of the symptoms of chronic sinusitis in children of more than 6 months was not a predictor of success of endoscopic sinus surgery in these children . - pubmed
Seven of 11 patients with WM had an M - protein & gt;3 g / dl and five patients had bone surveys performed that were negative for osteolytic disease . - pubmed
Cognitive function and fMRI in patients with multiple sclerosis : evidence for compensatory cortical activation during an attention task . - pubmed
Mild cognitive impairment has frequently been reported for patients in the early stages of multiple sclerosis . - pubmed
Expanded brain activation of multiple sclerosis patients with normal motor function compared with healthy controls during a finger tapping paradigm has previously been reported . - pubmed
Compensatory brain activation in patients with multiple sclerosis compared with normal controls may also be observed when the subjects are performing cognitive functions . - pubmed
All patients were within 3 years of diagnosis and were not suffering from a relapse at the time of investigation . - pubmed
The multiple sclerosis patients were compared with a control group of 21 healthy volunteers matched for handedness , age , years of education and sex . - pubmed
Univariate and multivariate analyses were performed to find any demographic parameters ( ie , sex , age , height , and body weight ) , clinical characteristics ( ie , nutritional or developmental status , co - infection with hepatitis viruses [ B or C ] or human immunodeficiency virus , presence of extrapulmonary tuberculosis , or medical history of liver disease ) , or individual antituberculosis agents used that would be associated with the likelihood of development of severe hepatotoxicity during antituberculous chemotherapy . - pubmed
Severe hepatotoxicity developed in 8 of the 99 eligible children , and all 8 of those children were younger than 5 years old . - pubmed
The univariate analysis revealed that the children in whom hepatotoxicity developed were significantly ( P & lt;.05 ) younger , were predominantly male , had extrapulmonary tuberculosis , and were given pyrazinamide more often than those who had no hepatotoxicity . - pubmed
However , the multivariate logistic regression analysis revealed that only age and the administration of pyrazinamide would have a significant contribution ( P & lt;.05 ) to the development of severe hepatotoxicity , with odds ratios of 143 ( 95 % confidence interval , 4.2 to 4934.9 ) and 0.60 ( 95 % confidence interval , 0.39 to 0.90 ) , respectively : the estimated probability of development of hepatotoxicity in a typical pediatric patient at 1 , 5 , and 10 years receiving pyrazinamide with rifampin ( INN , rifampicin ) and isoniazid would be 0.95 , 0.72 , and 0.16 , respectively . - pubmed
CONCLUSIONS : This study indicated that intensive monitoring of hepatotoxicity should be performed for younger children ( & lt;5 years ) receiving pyrazinamide for antituberculosis chemotherapy . - pubmed
While this may be appropriate for symptom control in patients with tumours that are not hormone responsive , patients with hormone dependent tumours will require safe and effective alternative treatments for menopausal symptoms . - pubmed
To determine whether maintained estrogen or progesterone levels affect kainic acid ( KA ) seizure patterns or the susceptibility of hippocampal neurons to death from seizures , ovariectomized Sprague - Dawley rats were implanted with estrogen pellets , 0.1 or 0.5 mg , that generated serum levels of 42.4 + /- 6.6 ( mean + /- SEM ) and 242.4 + /- 32.6 pg / ml or one to six capsules of progesterone that generated serum levels of 11.00 + /-.72 to 48.62 + /- 9.4 ng / ml . - pubmed
Progesterone reduced seizure severity in animals that received one to four implants ; compared with controls , no difference in seizure severity was noted for animals with six progesterone implants . - pubmed
The reduced seizures in progesterone - treated animals were accompanied by a reduction in the spread of hippocampal damage ( r(2 ) = 0.87 ; P & lt ; 0.05 ) . - pubmed
Likewise , in progesterone - treated rats , neuron survival and reduction in seizure scores were correlated ( r(2 ) = 0.76 ; P & lt ; 0.0001 ) . - pubmed
Indeed , in the estrogen - treated rats , neuronal death was significantly lower than that observed in progesterone - treated animals with equally severe seizures ( P & lt ; 0.05 ) . - pubmed
Small hepatocellular carcinomas in patients with liver cirrhosis : potentials and limitations of contrast - enhanced power Doppler sonography . - pubmed
Detection and characterization of focal liver lesions are critical for patients with liver cirrhosis . - pubmed
However , prospective studies in the assessment of patients with suspected hepatocellular carcinoma ( HCC ) in liver cirrhosis are rare . - pubmed
RESULTS : Of 42 persons ( 22 males and 20 females ) with OAG , 13 ( 31.0 % ) had PEX . - pubmed
coli causing hemorrhage and regression of an experimental mouse tumor . - pubmed
[ The effect of vitamin P on the experimental toxicity of tetracycline in guinea pigs ] . - pubmed
The relationship between basal and maximum acid output in normal subjects and patients with duodenal ulcer . - pubmed
The c1 - t mutants of bacteriophage lambda can form prophage at 36 degrees C but cause lysis of sensitive bacteria at temperatures above 42 degrees C. Growth of cultures at 42 degrees to 46 degrees C induces prophage replication and lysis in Escherichia coli K12 ( lambda c1 - t ) ; lysogenic strains containing wild - type prophage are not induced to lyse at these temperatures . - pubmed
[ CAUSE OF DEATH IN TRAUMATIZED PATIENTS . - pubmed
Actinobacillus pleuropneumoniae , the etiological agent of porcine pleuropneumonia , is able to survive on respiratory epithelia , in tonsils , and in the anaerobic environment of encapsulated sequesters . - pubmed
Pigs challenged with either of the two mutants in an aerosol infection model showed a lower lung lesion score than that of the A. - pubmed
The authors report 9 patients who presented with loss of consciousness ( syncope ) due to occlusive carotid artery diseases . - pubmed
The attack was associated with dehydration or hypotension in 5 patients . - pubmed
Cerebral angiography revealed occlusion of the unilateral internal carotid artery ( ICA ) in 7 patients , severe stenosis of the bilateral ICA in one , and occlusion of the unilateral ICA and severe stenosis of the contralateral ICA in one . - pubmed
No further episode of syncope occurred in all 9 patients during follow - up periods . - pubmed
Tyrosinemia resulting from administration of protein - dense infant diets was detected by newborn screening in two infants . - pubmed
Loss of normal tight junction functions constitutes a hallmark of human carcinomas . - pubmed
PATIENTS AND METHODS : Between January 2002 and January 2004 , 32 male patients with symptomatic urethral strictures ( 8 bulbar , 9 penile , 9 combined ) were treated with Ho : YAG - laser urethrotomy in our department . - pubmed
No intraoperative complications were encountered , although in 5 % of patients , a urinary - tract infection was diagnosed postoperatively . - pubmed
Spontaneous regression of optic pathways gliomas in three patients with neurofibromatosis type I and critical review of the literature . - pubmed
CASE REPORTS : The authors report their experience about three children ( two girls , one boy ; average age 1.6 years ) with a spontaneous regression of optic gliomas . - pubmed
The knowledge that this kind of tumor , particularly in young patients , may regress is important in the decision of the best therapeutic approach . - pubmed
Proteasome inhibition attenuates hepatic injury in the bile duct - ligated mouse . - pubmed
Our aims were to assess the effect of the proteasome inhibitor bortezomib on liver injury in the BDL mouse . - pubmed
Liver injury was assessed in 7 - day BDL mice treated with a single dose of bortezomib on day 4 after bile duct ligation . - pubmed
In conclusion , these data suggest that the proteasome inhibitor bortezomib reduces hepatocyte injury in the BDL mouse by mechanisms associated with a reduction in hepatocyte apoptosis , a decrease in Kupffer cell / macrophage number and activation , and increased hepatocyte proliferation . - pubmed
METHODS : Digital intubation was performed by 18 emergency medicine residents and 4 staff emergency medicine physicians on 6 different cadavers . - pubmed
New techniques to understand chromosome dosage : mouse models of aneuploidy . - pubmed
Mice are the organism of choice to help us try to tease apart the complex relationships between genotype and phenotype in aneuploidy and segmental aneusomy syndromes . - pubmed
As new technologies such as chromosome engineering and the creation of transchromosomic mice become routine , these will help us identify individual dosage - sensitive genes that are causative in specific syndromes and will enable us to produce mouse models to accurately recapitulate human chromosomal disorders . - pubmed
The aim of this study was to identify the molecular genetic defect and determine its functional consequences in a patient with type II Glanzmann thrombasthenia . - pubmed
Behavioural and psychological symptoms of dementia ( BPSD ) are a frequent problem in patients with dementia . - pubmed
Three studies suggested possible short - term efficacy , tolerability and safety of divalproex sodium for agitation and some other neuropsychiatric symptoms associated with dementia in elderly patients ; in two of these studies , the findings were obtained only on analysis of secondary outcomes . - pubmed
Further research is needed to determine the optimal use of divalproex sodium for the treatment of neuropsychiatric symptoms of dementia and the long - term benefits , if any , of its use in this patient population . - pubmed
Sleep disturbances are among the most common symptoms in patients who have acute episodes of mood disorders , and patients who have mood disorders exhibit higher rates of sleep disturbances than the general population , even during periods of remission . - pubmed
Recently , strains of Streptococcus bovis were reclassified as Streptococcus gallolyticus . - pubmed
Compared to strains representing previously derived phylogeny , including the S. - pubmed
equinus complex , the 16S rRNA - derived phylogeny of the strains investigated in this study demonstrated a paraphyletic group ( S. - pubmed
At three of the four farms most of the pregnant cows were affected with alopecia with or without pruritus in January , and 25 % of the cows in one herd died during the winter . - pubmed
The investigation indicated that CSS was associated with feeding moldy cereal straw to pregnant beef cows during the winter . - pubmed
Patients with grass pollen allergy were randomly allocated to four groups , and received daily a standardized tablet at different doses . - pubmed
Concurrent chemoradiotherapy for T4 patients with hypopharyngeal and laryngeal squamous cell carcinomas . - pubmed
OBJECTIVES : Concurrent chemoradiotherapy ( CCR ) was given for the previously untreated T4 hypopharyngeal and laryngeal squamous cell carcinoma patients and the response and survival rates were evaluated . - pubmed
RESULTS : Ten out of the 15 hypopharyngeal carcinoma patients and 4 out of the 8 laryngeal carcinoma patients showed a complete response at the primary sites . - pubmed
The 5 - year disease - specific survival rate was 59.4 % in all the patients , 51.9 % in the hypopharyngeal carcinoma patients , and 71.0 % in the laryngeal patients . - pubmed
Seven out of the 12 resectable hypopharyngeal carcinoma patients and 4 out of 8 laryngeal carcinoma patients were able to do without total laryngectomy . - pubmed
CONCLUSIONS : Based on these results , the survival rate in the hypopharyngeal and laryngeal T4 carcinoma patients treated by CCR seems to be satisfactory and the possibility of organ preservation for the advanced patients is indicated . - pubmed
METHODS : One hundred seventy - eight hospital - based asthmatic children and 277 community - based controls aged from 5 to 12 years were recruited in southern Taiwan . - pubmed
Diffuse axonal damage , myelin impairment , astrocytosis and inflammatory response following microinjections of NMDA into the rat striatum . - pubmed
METHODS : This is a secondary , qualitative analysis of video - recorded , semi - structured and open - ended interviews with the 130 community - dwelling patients with mild - to - moderate AD from the Video - Imaging Synthesis of Treating Alzheimer ' s Disease ( VISTA ) study - a four - month , randomized , placebo - controlled trial of galantamine . - pubmed
Epidemiological observations have shown that oxidative stress is one of the major sources of carcinogenesis , the top - ranked cause of human mortality worldwide . - pubmed
Both human cancers and mouse models have confirmed that mutations or altered expression of components of this pathway are associated with prostate tumors . - pubmed
[ Influence of Zea mays L. saponin ( ZMLS ) on ultrastructure of kidney and pancreas in diabetes rats induced by streptozocin ] . - pubmed
OBJECTIVE : To discuss the effect of Zea mays L. saponin ( ZMLS ) on ultrastructure of kidney and pancreas in the diabetes rats induced by streptozocin . - pubmed
METHOD : The diabetic rat model was established by injections of STZ , blood glucose , the ultrastructure of the kidney and pancreas were observed . - pubmed
We hypothesized that patients with anterior temporal abnormalities would exhibit impaired auditory naming , yet normal range visual naming , whereas patients with posterior temporal abnormalities would exhibit impaired performance on both tasks . - pubmed
Thirty - four patients with documented anterior temporal abnormalities and 14 patients with documented posterior temporal abnormalities received both naming tests . - pubmed
As hypothesized , patients with anterior temporal abnormalities demonstrated impaired auditory naming , yet normal range visual naming performance . - pubmed
Patients with posterior temporal abnormalities were impaired in visual naming ; however , auditory naming scores were intact . - pubmed
Although these group patterns were statistically significant , on an individual basis , auditory - visual naming asymmetries better predicted whether individual patients had anterior or posterior temporal abnormalities . - pubmed
Biomarkers of lung damage associated with tobacco smoke in induced sputum . - pubmed
The purpose of this narrative review is to summarize publications reporting cellular , soluble or volatile marker of obstructive lung disease in populations of healthy non - smokers and healthy smokers , in order to determine whether the biomarkers examined could be specifically associated with exposure to tobacco smoke rather than with inflammation and airway hyper - reactivity . - pubmed
We describe a patient who was admitted to our hospital with deep vein thrombosis at 18 weeks of gestation and who developed heparin - induced thrombocytopenia during her antenatal care . - pubmed
In culture , neonatal rat ventricular myocytes mature to form striated myocytes and electrically uncoupled skeletal myotubes simulate fibrosis seen in the healed IBZ . - pubmed
No adverse effects were reported except for temporary pruritus immediately after the application of pimecrolimus 1 % cream in one patient . - pubmed
CONCLUSION : Although the interpretation of efficacy was limited by the open - label , non - controlled study design and the small number of patients , this trial suggests that pimecrolimus 1 % cream may be a successful treatment choice for patients with resistant seborrheic dermatitis of the face . - pubmed
BACKGROUND : We studied the clinical characteristics and outcomes of patients undergoing pneumonectomy after preoperative concurrent chemoradiation for non - small cell lung cancer . - pubmed
METHODS : Clinical records of patients with non - small cell lung cancer who underwent pneumonectomy at our institution between 1995 and 2005 after preoperative concurrent chemoradiation were reviewed retrospectively . - pubmed
Of the 21 men and 8 women who were treated , 1 had stage IIB ( T3N0M0 ) and the remainder had stage IIIA or IIIB non - small cell lung cancer . - pubmed
Recurrences have been found in 11 patients ( 38 % ) , including brain metastases ( n = 6 ) , bone metastases ( n = 4 ) , liver metastases ( n = 2 ) , and cervical lymph node metastases ( n = 2 ) . - pubmed
One patient had a contralateral new primary lung cancer develop 70 months after undergoing pneumonectomy . - pubmed
Quality and quantity of diffuse and focal white matter disease and cognitive disability of patients with multiple sclerosis . - pubmed
CONCLUSIONS : The use of 3 T MRI in a sample of clinically stable MS patients shows the importance of WM disease in hampering processing speed and word retrieval . - pubmed
The impact of fatigue should be considered with the aim of improving quality of life and care of patients with epilepsy . - pubmed
Integrated population pharmacokinetics of etanercept in healthy subjects and in patients with rheumatoid arthritis and ankylosing spondylitis . - pubmed
Etanercept pharmacokinetics in patients with rheumatoid arthritis ( RA ) , ankylosing spondylitis ( AS ) , and psoriasis were assessed separately with distinct models using population pharmacokinetics methods of limited precision . - pubmed
This integrated analysis aimed to establish a framework to evaluate previously established population pharmacokinetic models of etanercept , and to identify consistent and important demographic and disease factors that affected etanercept pharmacokinetics in a diverse population of healthy subjects and patients with RA and AS . - pubmed
In this integrated analysis , cumulative rich and sparse etanercept concentration data from 53 healthy volunteers , 212 patients with RA , and 346 patients with AS were examined and compared using nonlinear mixed effect methodology implemented the in NONMEM VI software package . - pubmed
In adult patients with RA and AS , age and body weight do not significantly affect etanercept pharmacokinetics . - pubmed
HPV - immune response to infection and vaccination . - pubmed
Failure to develop effective CMI to clear or control infection results in persistent infection and , in the case of the oncogenic HPVs , an increased probability of progression to CIN3 and invasive carcinoma . - pubmed
The prolonged duration of infection associated with HPV seems to be associated with effective evasion of innate immunity thus delaying the activation of adaptive immunity . - pubmed
Assessing subtle structural changes in Alzheimer ' s disease patients . - pubmed
Lactococcus lactis as an adjuvant and delivery vehicle of antigens against pneumococcal respiratory infections . - pubmed
The progress made so far in the protective immune response induced by recombinant vaccines , the successful trials in animal models and the safety considerations of their application in humans suggest that the use of recombinant vaccines represents a good short - term option in the control of pneumococcal diseases . - pubmed
Five miRNAs of Epstein - Barr virus ( EBV ) were also detected in EBV - infected nasopharyngeal carcinoma cells , while they did not appear in non - virus infected cells . - pubmed
METHODS : We recruited 46 patients ( 27 men , 19 women ; median age 70 years ) with clinical stage I lung adenocarcinoma who had undergone pulmonary resection with mediastinal lymph node dissection . - pubmed
This article is devoted to assessing the adequacy and safety of total intravenous anesthesia based on constant dosed infusion of propofol and high thoracic epidural analgesia in thoracic surgical procedures requiring an artificial one - lung ventilation in patients with concomitant chronic cardiorespiratory disorders compared to TIVA without a high thoracic epidural analgesia . - pubmed
Delayed endovascular revascularization in a patient with progressive neurological deterioration from bilateral intracranial vertebral artery occlusions : case report . - pubmed
BACKGROUND AND IMPORTANCE : This article describes delayed endovascular revascularization in a patient with clinical and radiographic evidence of posterior circulation hemodynamic failure in the setting of intracranial occlusive lesions . - pubmed
CLINICAL PRESENTATION : A 48 - year - old man presented with a 6 - week history of progressive headache , nausea , and ataxia . - pubmed
Bilateral intracranial vertebral artery occlusions and a left posterior inferior cerebellar artery stroke were diagnosed , and the patient began warfarin therapy . - pubmed
Despite these measures , the patient developed dense lower cranial neuropathies , including severe dysarthria , decreased left - sided hearing acuity , and left facial droop . - pubmed
The patient underwent successful revascularization with intravascular Wingspan stents ( Boston Scientific , Natick , Massachusetts ) in a delayed fashion ( approximately 6 weeks after his initial stroke presentation ) . - pubmed
CONCLUSION : Patients with arterial occlusion should be evaluated acutely for potential revascularization . - pubmed
A subpopulation of patients will present with progressive deficits distinct from extracranial manifestations of vertebrobasilar insufficiency ; these patients should be considered for delayed revascularization . - pubmed
Selective changes of retroelement expression in human prostate cancer . - pubmed
Whether this re - expression really occurs in human cancers is largely unkown . - pubmed
In particular , LINE-1 hypomethylation does not lead to generalized overexpression , but specific human endogenous retrovirus - K proviruses display conspicuous changes in their expression hinting at significant functions during prostate carcinogenesis . - pubmed
Vibrio parahaemolyticus isolates from southeastern Chinese coast are genetically diverse with circulation of clonal complex 3 strains since 2002 . - pubmed
parahaemolyticus strains and 73.3%-76.9 % identity to the CDS24 of a Vibrio sp . - pubmed
PARTICIPANTS : Volunteers ( N=25 ) without low - back pain . - pubmed
These include surveillance of foodborne pathogens , microbial source tracking , risk assessment , and human populations at increased risk of infection by foodborne microbes . - pubmed
Vitamin D deficiency is associated with poor outcomes and increased mortality in severely ill patients . - pubmed
In this study , we assessed the correlation between circulating vitamin D levels and mortality rates in critically ill patients . - pubmed
Among the deceased patients , survival curves indicated that survival of patients with vitamin D deficiency was significantly shorter than those whose vitamin D concentration was & gt;20 ng / ml ( P & lt ; 0.05 ) ; the average survival time was 15.3 + - 12.4 days for vitamin D deficient patients compared with 24.2 + - 16.5 days among those with normal vitamin D levels . - pubmed
We recommend assessing the effects of vitamin D supplementation in critically ill patients . - pubmed
The symptom that improved most was photophobia ( improved in 19 patients , 82.6 % ) . - pubmed
By interrogating public databases , we have found that over - expression of this signature correlates with poor relapse - free survival in breast cancer patients . - pubmed
Ninety - nine liver metastases ( 72 patients ) , 48 hepatocellular carcinomas ( 42 patients ) , and six cholangiocarcinomas were treated . - pubmed
PATIENTS : A total of 28,581 patients , aged 18 to 65 years , who underwent craniotomy for a brain tumor . - pubmed
Patients with relapsed stage 4 neuroblastoma have an extremely poor long - term prognosis , making the investigation of new agents of interest . - pubmed
After 3 cycles of decitabine and vaccine , this patient achieved a complete remission and is now 1 year from his last treatment , with no evidence of tumor in his bone marrow or other sites . - pubmed
RESULTS : Of 385 eligible patients , six were excluded because of pre - existing hydronephrosis or suspected intra - operative ureteral injury . - pubmed
CONCLUSION : Mild hydronephrosis is a frequent finding after uncomplicated hysterectomy for benign pathology in otherwise asymptomatic patients . - pubmed
BACKGROUND : The Asian corn borer ( ACB ) , Ostrinia furnacalis ( Guenee ) , has become the most damaging pest in corn in south - east Asia . - pubmed
Bacillus thuringiensis ( Bt ) and Bt herbicide - tolerant ( BtHT ) corns have been developed to reduce borer attacks worldwide . - pubmed
PATIENTS : 75 consecutive revision TKA in 75 patients were included and stratified according to a BMI greater or smaller than 30 kg / m2 and a body weight greater or smaller than 90 kg . - pubmed
Noroviruses ( NoVs ) are important human pathogens associated with foodborne and waterborne gastroenteritis . - pubmed
However , the vast majority of human infections are associated with variants of a unique genotype , GII.4 . - pubmed
The presence of GIV NoV both in sewage and in clinical samples confirms that not only GI and GII NoVs but also GIV strains are circulating in humans . - pubmed
Data on the efficacy of ustekinumab in patients with moderate - to - severe Crohn ' s disease , especially in patients previously treated with infliximab , have been recently published . - pubmed
BACKGROUND : Many patients with moderate - to - severe atopic dermatitis ( AD ) require systemic immunomodulating treatment to achieve adequate disease control . - pubmed
PURPOSE OF REVIEW : A small proportion of patients with asthma have severe disease characterized by persistent airflow obstruction , airway hyperresponsiveness and eosinophilic airway inflammation . - pubmed
SUMMARY : In severe refractory asthma , both an understanding of the underlying pathophysiologic mechanisms driving airway inflammation and the identification of appropriate biomarkers in individual patients are critical in guiding the use of biologics and monoclonal antibodies that target the specific pathological processes . - pubmed
Proarrhythmic effect of " reverse mode switch " in a patient with long - QT syndrome . - pubmed
The results revealed that hypothyroid rats tended to eat less food and experienced substantial body weight gain , whereas the rats with T4 replacement tended to eat more food while continuing to lose weight . - pubmed
It accounts for approximately 10 % of pathologically confirmed dementias but has been demonstrated to be as prevalent as Alzheimer ' s disease in patients below the age of 65 . - pubmed
HRSV ( human respiratory syncytial virus ) is a serious cause of lower respiratory tract illness in infants and young children . - pubmed
Erratum : efficacy and tolerability of anticholinergics in korean children with overactive bladder : a multicenter retrospective study . - pubmed
The first steps for understanding the functions of DNA methylation and its regulation in mammalian development have led us to identify common ( epi)genetic mechanisms involved in the eight human congenital imprinting disorders . - pubmed
From 2008 to 2013 , 189 consecutive treatment - naive CHB patients receiving TDF ( n = 41 ) or ETV ( n = 148 ) for severe acute exacerbation were enrolled . - pubmed
In conclusion , TDF and ETV produce a similar treatment response and clinical outcome in patients with severe acute exacerbation of CHB . - pubmed
Bacteriocinogenic potential of a probiotic strain Bacillus coagulans [ BDU3 ] from Ngari . - pubmed
The strain BDU3 was identified as Bacillus coagulans by phenotypic and genotypic characterization . - pubmed
Early dynamic left intraventricular obstruction is associated with hypovolemia and high mortality in septic shock patients . - pubmed
INTRODUCTION : Based on previously published case reports demonstrating dynamic left intraventricular obstruction ( IVO ) triggered by hypovolemia or catecholamines , this study aimed to establish : ( 1 ) IVO occurrence in septic shock patients ; ( 2 ) correlation between the intraventricular gradient and volume status and fluid responsiveness ; and ( 3 ) mortality rate . - pubmed
METHOD : We prospectively analyzed patients with septic shock admitted to a general ICU over a 28 - month period who presented Doppler signs of IVO . - pubmed
RESULTS : During the study period , 218 patients with septic shock were admitted to our ICU . - pubmed
A rise & gt;=12 % in stroke index was found in 87 % of patients with IVO , with a drop of 47 % in IVO after fluid infusion . - pubmed
CONCLUSION : Left IVO is a frequent event in septic shock patients with an important correlation with fluid responsiveness . - pubmed
Objective means are needed to predict and assess clinical response in patients treated for invasive aspergillosis ( IA ) . - pubmed
Patients with proven or probable IA were prospectively enrolled , and serial GM and BDG levels and GM optical density indices ( GMI ) were calculated twice weekly for 6 weeks following initiation of standard - of - care antifungal therapy . - pubmed
Among 47 patients with IA , 53.2 % ( 25/47 ) and 65.9 % ( 27/41 ) had clinical response by weeks 6 and 12 , respectively . - pubmed
These results suggest that changes of biomarkers may be informative to predict and/or assess response to therapy and survival in patients treated for IA . - pubmed
Diabetes was induced by streptozotocin , and mRNA profiles of isolated glomeruli and sorted podocytes from diabetic and control mice were examined 10 weeks later . - pubmed
Expression of podocyte - specific markers in glomeruli was downregulated in diabetic mice compared with controls . - pubmed
However , expression of these markers was not altered in sorted podocytes from diabetic mice . - pubmed
Gastroprotective Effects of PMK - S005 against Ethanol - Induced Acute Gastric Damage in Rats . - pubmed
BACKGROUND / AIMS : This study aimed to examine the gastroprotective effects of PMK - S005 , which is a synthetic S - allyl - Lcysteine ( SAC ; a sulfur - containing amino acid ) , against acute ethanol - induced gastric damage in rats . - pubmed
Better understanding of the impact of age at reduction and surgical approach is important to reduce the risk of osteonecrosis in patients with DDH . - pubmed
Similarly , the odds of osteonecrosis after open reduction did not differ between patients treated after the age of 12 months compared with those treated at or before 12 months ( OR , 1.1 ; 95 % CI , 0.7 - 1.9 ; p = 0.7 ) . - pubmed
The first patient in whom the technique was used had a left - sided , 1.4 - cm , tuberculum meningioma . - pubmed
OBJECTIVE : We measured visual scanning behavior , using an eye - tracker , to explore attentional bias in the presence of competing stimuli to assess apathy in AD patients . - pubmed
METHODS : Mild - to - moderate AD patients ( Standardized Mini - Mental Status Examination , sMMSE > 10 ) were assessed for apathy ( Neuropsychiatric Inventory [ NPI ] apathy , Apathy Evaluation Scale [ AES ] ) . - pubmed
Participants were presented with 16 slides , each containing 4 images of different emotional themes ( 2 neutral , 1 social , 1 dysphoric ) . - pubmed
RESULTS : Of the 36 AD patients ( 14 females , age = 78.2 + -7.8 , sMMSE = 22.4 + -3.5 ) included , 17 had significant apathy ( based on NPI apathy > = 4 ) and 19 did not . - pubmed
The Legacy of Past Pandemics : Common Human Mutations That Protect against Infectious Disease . - pubmed
Lanolin for the treatment of nipple pain in breastfeeding women : a randomized controlled trial . - pubmed
The purpose of this study was to evaluate the effect of lanolin on nipple pain among breastfeeding women with damaged nipples . - pubmed
Breastfeeding women ( N = 186 ) identified as having nipple pain / damage were randomized to apply lanolin ( intervention group ; n = 93 ) or to receive usual postpartum care ( control group ; n = 93 ) . - pubmed
This study investigated whether tumor - associated macrophages ( TAMs ) have a role in altering NK cell function and phenotype using in vitro cocultures of murine NK cells with peritoneal or bone marrow - derived , M2 - polarized macrophages or TAMs isolated from spontaneous mouse breast tumors . - pubmed
Patients with anaplastic carcinoma and metastatic thyroid renal cell carcinoma were excluded . - pubmed
In multivariate analysis , including patient age and presence of malignancy , patient age was the only significant predictor of overall survival ( hazard ratio : 1.09 by year , 95 % confidence interval : 1.03 - 1.14 , p=0.00 ) . - pubmed
BACKGROUND : Host - specific environmental factors induce changes in Bacillus anthracis gene transcription during infection . - pubmed
Introduction : In patients with mechanical prosthetic heart valves or atrial fibrillation requiring anticoagulation to prevent thromboembolic events , several factors influence adherence and anticoagulation complications . - pubmed
MATERIAL AND SURGICAL TECHNIQUE : Our first case of PPOM was performed on a 54 - year - old woman who developed a complex incisional hernia after multiple abdominal operations . - pubmed
Extracorporeal life support is safe in trauma patients . - pubmed
INTRODUCTION : The role of extracorporeal life support ( ECLS ) in the critically ill trauma patient is poorly defined , possibly leading to the underutilization of this lifesaving therapy in this population . - pubmed
This study examined survival rates and risk factors for death in trauma patients who received ECLS . - pubmed
METHODS : Data from the National Trauma Data Bank was retrospectively reviewed to identify trauma patients who received ECLS from January 2012 to December 2014 . - pubmed
Analysis of specific anatomic locations of traumatic injury , including serious head / neck , thoracic , and abdominal injuries , revealed no impact on patient survival . - pubmed
CONCLUSIONS : Extracorporeal life support appears to be an effective treatment option in trauma patients with severe cardiopulmonary failure . - pubmed
Survival in trauma patients receiving ECLS is similar to that observed in the general ECLS population and this may represent an underutilized therapy in this population . - pubmed
MATERIALS AND METHODS : A total of 15 observers measured the temporal and nasal Van Herick scores from 18 patients , grouped into cohorts at outpatient glaucoma and corneal clinic . - pubmed
Moreover , many retrocopies of protein - coding genes are linked to human diseases , especially various types of cancer . - pubmed
STUDY DESIGN : In the study , 26 premolars were transplanted in 20 patients after traumatic tooth loss ( n = 16 ) or congenital aplasia ( n = 10 ) in the anterior maxilla . - pubmed
CONCLUSIONS : Here we showed that 24 h after experimental MI in rats in vivo , apoptosis was induced in the posterior non - in farcted LV wall . - pubmed
MATERIALS AND METHODS : We retrospectively reviewed the records of patients who underwent radical cystectomy for bladder cancer at our institution . - pubmed
Patients who experienced any fistula were identified . - pubmed
RESULTS : Of the 1,041 patients 31 ( 3.0 % ) experienced fistula formation . - pubmed
RATIONALE : Depressed patients robustly exhibit affective biases in emotional processing which are altered by SSRIs and predict clinical outcome . - pubmed
OBJECTIVES : The objective of this study is to investigate whether psilocybin , recently shown to rapidly improve mood in treatment - resistant depression ( TRD ) , alters patients ' emotional processing biases . - pubmed
In patients , this change was significantly correlated with a reduction in anhedonia over the same time period ( r = .640 , p = .010 ) . - pubmed
Patients : One hundred four newly diagnosed T2DM ( nT2DM ) , 109 impaired glucose tolerance ( IGT ) , and 128 healthy individuals were recruited for this study . - pubmed
Importance : Locoregional failure for patients with locally advanced bladder cancer ( LABC ) after radical cystectomy ( RC ) is common even with chemotherapy and is associated with high morbidity and mortality . - pubmed
Patients with bladder cancer 70 years or younger having 1 or more risk factors ( & gt;=pT3b , grade 3 , or positive nodes ) with negative margins after radical cystectomy plus pelvic lymph node dissection were eligible . - pubmed
Oral examination of 254 school children aged 6 - 18 years revealed an overall dental caries prevalence of 79.5 % . - pubmed
Neuroprotective Effects of Cyclosporine in a Porcine Pre - Clinical Trial of Focal Traumatic Brain Injury . - pubmed
The aim of the present study was to evaluate the efficacy of a novel and cremophor / kolliphor EL - free lipid emulsion formulation of cyclosporine in a translational large animal model of TBI . - pubmed
A mild - to - moderate focal contusion injury was induced in piglets using a controlled cortical impact device . - pubmed
In this study , we have demonstrated efficacy using a novel cyclosporine formulation in clinically relevant and translatable outcome metrics in a large animal model of focal TBI . - pubmed
CONCLUSIONS / IMPLICATIONS FOR PRACTICE : The results of this study indicate that the dialogue sessions using Steno Balance Cards are beneficial for patients with T2DM in terms of improved glycemic control and quality of life . - pubmed
The authors thus evaluated the relationship between timing of resumption of beta blockers and atrial fibrillation in patients recovering from noncardiothoracic and nonvascular surgery . - pubmed
After propensity score matching on baseline and intraoperative variables , 1,924 patients who did resume beta blockers by the end of postoperative day 1 were compared with 973 patients who had not resumed by that time on postoperative atrial fibrillation using logistic regression . - pubmed
RESULTS : Of propensity score - matched patients who resumed beta blockers by end of postoperative day 1 , 4.9 % ( 94 of 1,924 ) developed atrial fibrillation , compared with 7.0 % ( 68 of 973 ) of those who resumed thereafter ( adjusted odds ratio , 0.69 ; 95 % CI , 0.50 - 0.95 ; P = 0.026 ) . - pubmed
Patients who resumed beta blockers on day of surgery had an atrial fibrillation incidence of 4.9 % versus 5.8 % for those who started thereafter ( odds ratio , 0.84 ; 95 % CI , 0.67 - 1.04 ; P = 0.104 ) . - pubmed
Effect of dimethyl fumarate on neuroinflammation and apoptosis in pentylenetetrazol kindling model in rats . - pubmed
RESULTS : The results showed reduction in the seizure score , percentage of kindled rats and neurological damage score in DMF treated rats . - pubmed
( hairy nightshade ) plants with numerous leaf lesions and moderate defoliation were seen . - pubmed
Radial growth responses of these strains on rye grain agar amended with 1 , 10 , or 100 mug per ml of metalaxyl ( Ridomil 2E ) yielded 50 % effective dose values greater than 100 mug per ml , since percentage growth at the highest fungicide concentration exceeded 50 % of the no metalaxyl control . - pubmed
These resistance levels are typical of the metalaxyl - insensitive strains of P. - pubmed
To our knowledge , this is the first report of infection of S. - pubmed
Improved treatment outcome of pembrolizumab in patients with nonsmall cell lung cancer and chronic obstructive pulmonary disease . - pubmed
This study aimed to investigate the clinical impact of COPD on the treatment response to ICIs in a large number of patients with NSCLC . - pubmed
In total , 133 patients with spirometry test results were retrospectively identified among those who received palliative pembrolizumab for NSCLC . - pubmed
Spirometry - based COPD was present in 59 ( 44 % ) patients . - pubmed
Patients with COPD had better OS ( hazard ratio [ HR ] for death , 0.45 ; 95 % confidence interval [ CI ] , 0.26 - 0.78 ) and PFS ( HR for disease progression or death , 0.50 ; 95 % CI , 0.31 - 0.79 ) than those without COPD . - pubmed
Spirometry - defined COPD was associated with a significantly longer OS and PFS in patients with NSCLC treated with palliative pembrolizumab . - pubmed
Identifying coexisting COPD could predict favorable treatment outcomes in patients with NSCLC treated with pembrolizumab . - pubmed
A metagenomic study of patients with alveolar osteitis after tooth extraction . - pubmed
Microbiological samples were taken from the sockets of 10 patients with dry socket after tooth extraction ( AO group ) and 10 patients in whom exodontia resulted in no postoperative complications ( control group ) . - pubmed
Prevotella nanceiensis , Actinomyces odontolyticus , Treponema maltophilum , Veillonella dispar , Tannerella forsythia , and Leuconostoc mesenteroides were found in several patients with alveolar osteitis , with an abundance greater than 0.5 % , and were absent in all the control group samples . - pubmed
Correlations of somatic traits and postural defects in girls and boys aged 10 - 12 . - pubmed
BACKGROUND : The aim of the study was to analyse correlations between somatic features and variables of postural defects in girls and boys aged 10 - 12 . - pubmed
AIMS : Ligation of the urethra to create partial bladder outlet obstruction has widely been used as an animal model of bladder obstruction , although obstructive bladder dysfunction may be due to both mechanical and functional obstruction . - pubmed
Previous studies in rodents have demonstrated that long - term nitric oxide ( NO ) deficiency can lead to detrusor overactivity , and lack of NO may thus cause impairment of bladder outlet relaxation . - pubmed
SIGNIFICANCE : These findings suggest that chronic administration of L - NAME to rats induces bladder hyperactivity with residual urine , and may provide a useful model of functional bladder obstruction . - pubmed
Moreover , the original studies employed different clinical assessments and included manic patients taking other drugs , which made it impossible to determine whether the resolution of symptoms was due to valproate therapy alone . - pubmed
Osteonecrosis of the femoral head is the most common complication with identified risk factors including fracture type , patient 's age , degree of displacement , timing to reduction , and stability of fixation . - pubmed
BACKGROUND : Tobacco use , alcohol use , and sugar - sweetened beverage consumption are each associated with increased cancer - risk . - pubmed
The primary aim of this study is to evaluate the effect of trauma - informed yoga , drumming , and psychoeducation compared to control on tobacco use , alcohol use , and sugar - sweetened beverage consumption among community - based adults . - pubmed
Tai Chi exercise and functional electrical stimulation of lower limb muscles for rehabilitation in older adults with chronic systolic heart failure : a non - randomized clinical trial . - pubmed
Exercise - based training decreases hospitalizations in heart failure patients but such patients have exercise intolerance . - pubmed
A total of 1,084 older adults with chronic systolic heart failure were included in a non - randomized clinical trial ( n=271 per group ) . - pubmed
Accumulating evidence from animal and human studies supports the notion that physical exercise can enhance neuroplasticity and thus reduce the risk of several neurodegenerative diseases ( e.g. - pubmed
We sought to quantify the multiaxial mechanical properties of murine dissecting aneurysm samples by combining in vitro extension - distension data with full - field multimodality measurements of wall strain and thickness to inform an inverse material characterization using the virtual fields method . - pubmed
Preliminary safety and imaging efficacy of the near - infrared fluorescent contrast agent DA364 during fluorescence - guided surgery in dogs with spontaneous superficial tumors . - pubmed
Preliminary safety and imaging efficacy of the near - infrared fluorescent probe DA364 were evaluated during surgical resection of spontaneous solid tumors in 24 dogs . - pubmed
Impact of chronic kidney disease on long - term outcome of patients with valvular heart defects . - pubmed
Coexistence of chronic kidney disease ( CKD ) in patients with VHD increases the risk of death and affects further therapeutic strategy . - pubmed
MATERIAL AND METHODS : The inclusion criteria were met by 1025 patients with moderate and severe VHD . - pubmed
CKD occurred in 37.1 % ( N = 380 ) patients mostly with mitral stenosis ( 50 % , N = 16 ) and those with severe MVI ( 44.8 % , N = 94 ) . - pubmed
Regardless of the stage , chronic kidney disease is an additional factor affecting the prognosis in patients with heart defects . - pubmed
The monitoring of renal function in patients with VHD should be crucial as well as the implementation of treatment at an early stage . - pubmed
Here , we discuss a case of acute liver failure ( ALF ) with severe lactic acidosis in a 75 - year - old female with diffuse large B - cell lymphoma ( DLBCL ) . - pubmed
The patient was admitted with nausea , fevers , and mild acidosis . - pubmed
Although radiographic imaging did not demonstrate any liver abnormality , the patient soon developed signs of ALF along with severe lactic acidosis . - pubmed
This case highlights an uncommon manifestation of DLBCL and suggests that an accelerated timeline for beginning chemotherapy may be warranted in patients with high clinical suspicion of secondary hepatic lymphoma . - pubmed
The difference in detection rates of thrombophlebitis by physician and routine observation along with the demographic and clinical variables contributing to thrombophlebitis in hospitalized children were studied . - pubmed
Obstetric anal sphincter injuries ( OASIS ) in multiparous women with the use of epidural anaesthesia : A retrospective cohort study . - pubmed
RESULTS : There were 14 124 multiparous women who met the inclusion criteria ; spontaneous labour is associated with an increased risk of OASIS at adjusted odds ratio ( aOR ) 1.46 , P = 0.012 . - pubmed
Women with epidural use had significantly lower chances of sustaining OASIS in normal vaginal births and instrumental vaginal births . - pubmed
CONCLUSION : The use of epidural analgesia in multiparous women is associated with a reduction in anal sphincter injuries . - pubmed
Moreover , in this setting , the observation of the late - onset toxicity endpoint could be precluded by trial discontinuation due to death , progression , patient withdrawal , or physician discretion , defining a competing event to toxicity . - pubmed
A non - invasive tool for early detection of acute leukemia in children using a paper - based optoelectronic nose based on an array of metallic nanoparticles . - pubmed
Macrophage and neutrophil responses , bacterial dissemination , and liver damage were assessed following i.v . - pubmed
infection with a pathogenic strain of S. - pubmed
The 5 patients were 41 , 51 , 54 , 76 , and 76 years of age when initial symptoms of pelvic mass or pain appeared . - pubmed
Due to its low incidence , both multicenter clinical studies and molecular studies are required to provide gynecologists with a better understanding and guidance for future management of patients with ovarian fibrosarcoma . - pubmed
Human and monkey eye globes with retinal detachment served as controls . - pubmed
METHODS : Retrospective longitudinal study of patients with retinal pigment epithelium ( RPE ) tears secondary to age - related macular degeneration ( AMD ) . - pubmed
RESULTS : This study included 32 eyes from 31 patients ( 19 female and 12 male ) , with RPE tears secondary to AMD . - pubmed
( 1977 ) , transhepatic injection of oesophageal varices has been performed under local anaesthesia in 9 patients with portal hypertension ( 11 procedures ) . - pubmed
Bleeding resumed within 2 days of radiologically satisfactory occlusion in 2 patients and at 1 , 3 , 4 and 10 months after 4 procedures in 3 patients . - pubmed
There were 2 hospital deaths , both in alcoholic patients with poor hepatic function . - pubmed
In spite of the apparently high morbidity we consider that there is a place for this technique in tiding over patients who are bleeding from oesophageal varices and are medically unsuitable for any surgical procedure . - pubmed
A model of salmonella enteritis : the behaviour of Salmonella enteritidis in chick intestine studies by light and electron microscopy . - pubmed
Separate and combined effect of D hypovitaminosis and poor protein diet on the parameters of lipid metabolism in the blood serum and liver was investigated experimentally in albino rats . - pubmed
The lipid changes in the liver of the test animals in simultaneous deficiency of protein and vitamin D were similar to those in protein deficiency . - pubmed
[ Medical rehabilitation of patients with central nervous system injuries ] . - pubmed
[ Acute renal failure in children ] . - pubmed
Persistent vaginal cornification in mice treated with estrogen prenatally . - pubmed
Susceptibility of south Indian strains of Mycobacterium tuberculosis to tuberactinomycin . - pubmed
A total of 114 strains of Mycobacterium tuberculosis isolated from sputum samples of 114 patients of pulmonary tuberculosis in south India , were coded and tested for their in vitro susceptibility to tuberactinomycin ( Tum ) incorporated in Lowenstein - Jensen ( LJ ) medium . - pubmed
Western - immunoblotting gave indirect evidence for infection with Taenia crassiceps , a dog 's tapeworm . - pubmed
Increased bronchial reactivity to cholinergic stimulation is well recognized in patients with bronchial asthma . - pubmed
The case of a young patient who presented with severe hemolysis after mitral valve repair is presented . - pubmed
We studied verbal and visual short term memory , learning capabilities and long term retention in a sample of 96 patients with Parkinson ' s Disease ( PD ) and 42 controls matched by sex , age , years of education and verbal intelligence . - pubmed
Forty - one per cent of patients had impairment in visual short term memory , and this impairment is related with bradykinesia and correlated with age of onset . - pubmed
Twenty - seven patients with elbow joint dislocation were reviewed and treated between 1979 and 1983 . - pubmed
57 patients with duodenum ulcer were examined . - pubmed
In conclusion , the isolated glomerulus model allows us to demonstrate the direct vasoconstrictive effect of CsA , that can in part explain the renal functional changes and the acute renal failure often described in human clinic . - pubmed
A 3 - year - old child experienced edema of the face and extremities approximately 2 weeks after being stung on the legs , scrotum , and penis by " fire ants " ( Solenopsis invicta ) . - pubmed
The Authors stress the frequency of human hydatidosis , still high in Italy , and the severity of the above mentioned complication . - pubmed
A 20 - year - old man suffered a closed head injury followed by symptoms of right - sided labyrinthine concussion with complete clinical recovery within 3 weeks . - pubmed
A patient with a rare dermatosis , actinic reticuloid , is described . - pubmed
Vomiting occurred in 1 patient in whom the MMC was recorded only on the third postoperative day . - pubmed
After completion of AM kindling and the repetitive induction of kindled convulsion , the percentage of time spent in rapid eye movement sleep ( REMS ) significantly decreased , although the animals began to spend significantly more time in sleep . - pubmed
[ The effects of immuno - chemotherapy , hyperthermia and irradiation on the growth of human renal cell carcinoma ] . - pubmed
In order to investigate more effective treatments for advanced renal cell carcinoma , experiments were performed as to inhibitory effects on the growth of KPK 1 cells derived from a human renal carcinoma . - pubmed
An investigation has been made with regard to the clinical picture of 87 terminally ill patients with lung cancer . - pubmed
3 ) The most frequent cause of death in these patients was respiratory failure , due to progress of cancer , then infection , pleural , or pericardial effusion , or interstitial pneumonitis . - pubmed
Assessment of pancreatic islet - cell population in the hyperglycemic athymic nude mouse : immunohistochemical , ultrastructural , and hormonal studies . - pubmed
Previous studies in diabetic animal models have demonstrated altered pancreatic islet - cell populations . - pubmed
To further characterize the diabetic syndrome in our athymic nude mouse colony , we studied the population of endocrine cells in pancreatic islets of 4 - week - old normoglycemic and 8 - week - old hyperglycemic athymic nude ( nu / nu ) mice using immunohistochemistry , morphometry , and electron microscopy . - pubmed
The disposition and kinetics of intravenous N - acetylcysteine in patients with paracetamol overdosage . - pubmed
Seventeen patients received standard treatment with intravenous N - acetylcysteine for 18 episodes of severe poisoning with paracetamol ( acetaminophen ) . - pubmed
The elimination of N - acetylcysteine was not impaired in the patients with severe liver damage , and the pharmacokinetic variables and plasma concentrations were similar in patients with and without hepatotoxicity . - pubmed
Percutaneous balloon valvuloplasty and coronary angioplasty for the treatment of calcific aortic stenosis and obstructive coronary artery disease in an elderly patient . - pubmed
An 81 - year - old man with severe calcific aortic stenosis and coronary artery disease who refused surgical therapy was treated with sequential percutaneous balloon aortic valvuloplasty ( PBAV ) and percutaneous transluminal angioplasty . - pubmed
Thus , combined therapy with PBAV and PTCA is technically feasible in selected elderly patients with calcific aortic stenosis and anatomically suitable coronary artery disease . - pubmed
[ Comparison of the course of chronic diarrhea without permanent damage of the mucosa of the small intestine with the course of celiac disease in children ] . - pubmed
There is currently some concern over the potential risk to man from its use , since it has been found to cause liver tumours in mice , following the administration of very large doses . - pubmed
Following a single oral dose of 500 mg cinnamyl anthranilate / kg body weight to B6C3F1 mice peak plasma levels of unchanged compound were reached in 30 min , and were higher in males than in females . - pubmed
The histogenesis of mammary tumours induced in the rat by chemical carcinogens . - pubmed
Letter : Studies of resistance to long - acting adrenergic beta - stimulators in asthmatic patients . - pubmed
Supercooling injury in the egg cell of the sea urchin . - pubmed
Since larvicidal treatment to reduce the numbers of Culex fatigans , the tropical house mosquito , offers a promising means of preventing the spread of filariasis , an assessment was made of the liability of C. - pubmed
[ Dehydration of the human organism at high altitudes ] . - pubmed
[ Use of digoxin in the treatment of cardiac insufficiency in young children with congenital defects of the heart ] . - pubmed
Intestinal ischemic shock in germ - free animals . - pubmed
Data from patients were related to a control group of 38 patients with gastrointestinal disease but without pancreatic diseases . - pubmed
[ Idiopathic thrombocytopenic purpura : diagnosis and therapy in 46 patients ] . - pubmed
The hematological and immunological data of 46 patients with idiopathic thrombozytopenic purpura ( ITP ) and their response to treatment are reported . - pubmed
( 5 ) Fatal hemorrhages are very rarely seen in adults with ITP . - pubmed
Altered tumor growth in vivo after immunization of mice with antitumor antibodies . - pubmed
A comparison has been made between the growth patterns of two spontaneously appearing mammary adenocarcinomas in murine bone marrow radiation chimeras and in mice preimmunized with monoclonal antibodies ( MAb ) detecting embryo - associated antigenic determinants . - pubmed
A correlation was seen between the ability of the embryo - immunized chimeras to produce cytotoxic antibody to the tumors , as assessed by an antibody - dependent cellular cytotoxic assay , and the permissiveness of the mice for growth of a tumor transplant . - pubmed
In addition , mice deliberately preimmunized with cytotoxic MAb ( antibody - dependent cellular cytotoxic assay ) allowed more rapid growth specifically of that tumor earlier found to be most sensitive to the MAb used for immunization . - pubmed
By comparing the changing antigenic phenotype of tumor cells serially passaged through different immunized , nonimmunized mice , evidence was found suggesting that immunization could cause either antigen modulation of transferred tumor cells or a ( transient ) selective advantage to antigenically discrete subpopulations within the heterogeneous tumor population . - pubmed
Finally , we have studied the growth pattern of tumor cells transplanted into mice immunized with rabbit antibodies directed against the murine MAb . - pubmed
In this case , tumor growth was slowed preferentially for the tumor reactive with the specific MAb , and again , predictable changes in the antigenic spectrum of tumor cells harvested from these animals were observed . - pubmed
Our overall findings are interpreted in terms of the involvement of networks of antibodies reacting with embryo - associated antigens in the regulation of growth of the murine mammary adenocarcinomas studied . - pubmed
Maternal determinants of oral clefts have been documented in studies of experimental animals but not of humans . - pubmed
The study documents the existence of maternal determinants of CLP in humans . - pubmed
A chronic vitamin B6 deficiency in rats resulted in a non - specific increase ( 44- 51 % ) in the in vitro intestinal uptake of both essential ( Ca and Zn ) and non - essential toxic metal ( Cd ) ions , whereas an acute B6 - deficient state only affected the Zn uptake rate . - pubmed
One patient suffered sudden chest pain shortly after an injection of morphine , and one patient had moderate hypoventilation after buprenorphine ; both patients recovered uneventfully . - pubmed
Human papillomavirus ( HPV ) specifically infect stratified epithelial cells , causing benign and malignant neoplasia . - pubmed
A comparative investigation of ultrastructural changes in the lungs of 28 cardiosurgical patients operated upon under conditions of bubble and membrane oxygenation of blood has established that the following trends are perspective for lessening the disturbances of the lung ultrastructure in operations on the open heart : shorter time of the first parallel blood flow when using bubble oxygenation , less trauma of the heart during artificial blood circulation due to the improved perfusion system , realization of the conditions of extrapulmonary oxygenation of blood , responsible for the prevention of hypoxic injuries of the lungs . - pubmed
Infectious osteitis pubis in an HIV seropositive female . - pubmed
These studies suggest that activated leukocytes produce vasoconstriction by the release of vasoactive factor(s ) , and thus may contribute to the pathogenesis of cardiovascular complications in patients with atherosclerosis . - pubmed
Poliovirus type 1 isolated from a vaccine - associated case of paralytic poliomyelitis in Brazil . - pubmed
This study reports a type 1 poliovirus strain isolated in Brazil from a case classified as vaccine - associated paralytic poliomyelitis ( VAPP ) . - pubmed
The patient 's parents , who are first cousins , are asymptomatic and have only minor reductions in platelet aggregation . - pubmed
Superficial , non - lethal infection was produced in mice by injecting Pseudomonas aeruginosa into the skin windows . - pubmed
It has been demonstrated that MMC does not inhibit muscle reattachment and might inhibit adhesions and scar formation in the rabbit . - pubmed
We investigated in a rabbit model effectiveness of MMC in reducing the formation of postoperative adhesions following reoperations and the tensile strength of the new musculo - scleral junction . - pubmed
We recently encountered a patient with thrombosis of the superior sagittal sinus of an idiopathic cause . - pubmed
Whereas the patient suffered a complication with subacute subdural haematoma , he was successfully treated with the combination of these therapies . - pubmed
Lesions associated with infectious keratoconjunctivitis in alpine ibex . - pubmed
Following a severe infectious keratoconjunctivitis ( IKC ) epizootic in free - ranging alpine ibex ( Capra ibex ibex ) in Switzerland in 1993 , 19 animals were examined from six different populations . - pubmed
The microbiological findings indicate that Mycoplasma conjunctivae is the primary pathogenic agent causing IKC in this species in Switzerland . - pubmed
The patient was a 68 - year - old man with no previous clinical history of gastro - oesophageal reflux disease . - pubmed
Patients with LDLR defects had a significantly higher risk of myocardial infarction , coronary artery bypass graft , positive coronary angiography , atherosclerotic plaques in the carotid arteries and CAD ( p<0.01 ) than patients with FDB . - pubmed
CAD was present in 33 % and plaques in the carotid arteries in 82 % of the patients with LDLR defects . - pubmed
BACKGROUND : Because activation of platelets and of the coagulation system are interdependent mediators of thrombosis , platelet activation was characterized in whole blood in the presence of anticoagulants used to assess platelet function in vitro or as treatment for patients with occlusive arterial disease . - pubmed
An epithelial cell line , NPC - BM1 , was established from a bone marrow biopsy of a female Taiwanese patient with nasopharyngeal carcinoma ( NPC ) . - pubmed
Histopathology of the bone marrow biopsy and xenografts grown in severe combined immunodeficiency mice showed that the tumor was a nonkeratinizing , poorly differentiated carcinoma . - pubmed
Further validation of SV40 - like DNA in human pleural mesotheliomas . - pubmed
PATIENTS AND METHODS : During the period 1990 till 1997 , 292 patients underwent in our institution in total 354 ureteroscopies for ureteric lithiasis . - pubmed
Infants with AIDS - related symptoms exhibited undetectable or very low levels of HIV - specific cellular immunity during the first year of life , whereas those with a slowly progressive disease showed evidence of such immunity between their second and ninth month . - pubmed
METHODS : A consecutive series of 374 patients who had a total of 409 anterior cervical arthrodeses for the treatment of cervical spondylosis with radiculopathy or myelopathy , or both , were followed for a maximum of twenty - one years after the operation . - pubmed
METHODS : In 45 patients with a high clinical likelihood of renovascular hypertension ( RVH ) and unimpaired renal function , dynamic imaging was performed after an intravenous bolus injection of 148 MBq ( 99m ) Tc MAG3 for both baseline renoscintigraphy and captopril renography following oral application of 50 mg captopril . - pubmed
RESULTS : The number of kidneys that had a change of & gt;/=5 % in RCA values was 12 ( 27.2 % ) in normal kidneys , 7 ( 58.3 % ) in the patients with bilateral RAS , 14 ( 82.3 % ) in the patients with unilateral RAS , and 21 ( 72.4 % ) in overall kidneys with RAS . - pubmed
Gruppo Italiano di Studi Epidemologici in Nefrologia ( Gisen ) In the Ramipril Efficacy in Nephropathy study , ramipril decreased the rate of GFR decline ( deltaGFR ) and progression to end - stage renal disease ( ESRD ) in 352 patients with proteinuric chronic nephropathies . - pubmed
Hepatoblastoma with erythrocytosis in a young female horse . - pubmed
The prognosis for horses with hepatoblastoma is grave . - pubmed
One - year follow - up of 2829 patients with moderate to severe lower urinary tract symptoms treated with alfuzosin in general practice according to IPSS and a health - related quality - of - life questionnaire . - pubmed
OBJECTIVES : To determine the effectiveness of alfuzosin on symptom reduction , patients ' perceived health - related quality of life ( HRQL ) improvement , adverse outcomes , treatment failure , and progression to acute urinary retention and prostate surgery in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia ( BPH ) in a 1 - year prospective , open - labeled study . - pubmed
CONCLUSIONS : This study confirms the effectiveness of alfuzosin and the need to include HRQL measurement in the decision - making process when assessing patients with lower urinary tract symptoms . - pubmed
A multiplex PCR was employed to amplify unique conserved sequences of DNA from the pathogens Haemophilus influenzae , Neisseria meningitidis and Streptococcus pneumoniae from cerebrospinal fluid samples of patients suffering from acute pyogenic meningitis . - pubmed
Ten single - rooted teeth from 8 patients with advanced adult periodontitis were included . - pubmed
The impact of liver dysfunction on outcome in patients with multiple injuries . - pubmed
To clarify the role of the hepatic dysfunction after traumatic injury we retrospectively reviewed all trauma patients with an Injury Severity Score & gt ; or = 14 admitted from January 1 , 1994 through June 30 , 1997 for the presence of hepatic dysfunction defined as a serum bilirubin & gt ; or = 2.0 mg / dL. - pubmed
Of the 1962 patients who met the entry criteria 154 developed hepatic dysfunction during their hospital stay . - pubmed
Patients with hepatic dysfunction were older ( 46 + /- 2 versus 41 + /- 1 years ) , were more severely injured ( Injury Severity Score 31.5 + /- 0.9 versus 23.3 + 0.2 ) , and had a lower prehospital blood pressure ( 102 + /- 3 versus 117 + /- 1 mm Hg ) compared with patients who did not develop hepatic dysfunction . - pubmed
Patients with hepatic dysfunction were more likely to present with shock as reflected in a lower initial emergency room blood pressure ( 109 + /- 3 versus 128 + /- 1 mm Hg ) and base deficit ( -6.9 + /- 0.6 versus -3.5 + /- 0.1 mEq / L ) . - pubmed
Perfusion brain SPECT and statistical parametric mapping analysis indicate that apathy is a cingulate syndrome : a study in Alzheimer ' s disease and nondemented patients . - pubmed
According to ICD 10 diagnostic criteria , 28 patients had Alzheimer dementia ( demented : diagnostic group 1 ) , and 13 had organic personality disorders or mild cognitive impairment not attributable to dementia ( nondemented : diagnostic group 2 ) . - pubmed
Separation of free amino acids in human plasma by capillary electrophoresis with laser induced fluorescence : potential for emergency diagnosis of inborn errors of metabolism . - pubmed
Amino acid profiles for both normal donor plasma samples and plasma samples of patients suffering from phenylketonuria , tyrosinemia , maple syrup urinary disease , hyperornithinemia , and citrullinemia are studied . - pubmed
We report a 69 years old woman with a history of one month of vertigo , nausea , vomiting and diarrhea . - pubmed
At the 4th day of admission , the patient was again stuporous and with spastic quadriplegia . - pubmed
RESULTS : Omalizumab treatment resulted in significantly fewer asthma exacerbations per subject and in lower percentages of subjects experiencing an exacerbation than placebo treatment during the stable steroid phase ( 0.28 vs 0.54 [ P = .006 ] and 14.6 % vs 23.3 % [ P = .009 ] , respectively ) and during the steroid reduction phase ( 0.39 vs 0.66 [ P = .003 ] and 21.3 % vs 32.3 % [ P = .004 ] , respectively ) . - pubmed
Prediction of wall motion recovery from the left anterior descending coronary artery velocity pattern recorded by transthoracic doppler echocardiography in patients with anterior wall myocardial infarction retrospective and prospective studies . - pubmed
Patients with a shorter DHT of diastolic coronary flow velocity have a poorer functional outcome among patients with anterior AMI . - pubmed
Role of the serotoninergic system in the acceleration of sexual maturation in wild Norway rats selected for reduced aggressiveness toward humans . - pubmed
They also suggest that the acceleration in sexual maturation of domesticated rats could result from changes in the ontogenetic dynamic of hypothalamic serotonin induced by a selection for low aggressiveness towards man . - pubmed
Psoriasis is recognized as the most common T cell - mediated inflammatory disease in humans . - pubmed
The disease - related gene map provides new insights into the pathogenesis of psoriasis , wound healing and cellular - immune reactions occurring in human skin as well as other T cell - mediated autoimmune diseases . - pubmed
Preparing patients with asthma for discharge . - pubmed
Kava - induced fulminant hepatic failure . - pubmed
Here we report that a Wolbachia strain feminizes an insect host , Ostrinia furnacalis . - pubmed
The present findings indicate that the Wolbachia infection induces feminization of genetic males in O. - pubmed
Differences in the Wolbachia - induced feminization in O. - pubmed
Our findings over 5 years suggest that the infection has been maintained at a low prevalence in the O. - pubmed
[ OSCILLOGRAPHIC STUDIES IN PATIENTS WITH CHRONIC LUNG DISEASES ] . - pubmed
[ SERO - EPIDEMIOLOGICAL INVESTIGATION OF ADENOVIRUS INFECTIONS MADE WITH THE GEL DIFFUSION METHOD ] . - pubmed
The objectives were to determine the sociodemographic profile , risk category , and prevalence of HIV infection amongst people attending a confidential clinic providing counselling , medical advice and results of HIV antibody testing on the same day of consultation . - pubmed
Thirty of the HIV antibody - positive individuals were asymptomatic , 14 were symptomatic and three were diagnosed with an AIDS - defining condition . - pubmed
The continuing high HIV seroprevalence among individuals from African countries suggests that this population require specific targeting for HIV risk reduction and information on the advantages of early diagnosis and treatment . - pubmed
Infection studies on human cell lines with porcine circovirus type 1 and porcine circovirus type 2 . - pubmed
Infection of PCV1 was observed with 293 , Hela and Chang liver cells , infection with PCV2 only in Rd cells . - pubmed
When virus - free cells were inoculated with the supernatant of PCV - infected human cells , the infection was not passed . - pubmed
CONCLUSION : Although PCV gene expression and replication took place in human cells , the infection is non - productive . - pubmed
Because of the uncertain predictive value of animal models of neuropathic pain , it is essential to consider rational strategic approaches to selecting the most likely candidate targets . - pubmed
RESULTS : There were 20 female patients undergoing surgical treatment for PAOD during the study period , aged from 57 to 91 years , with an average of 73.7 + /- 2.2 . - pubmed
Four patients presented with rest pain . - pubmed
Twelve patients presented with gangrene of lower limbs . - pubmed
CONCLUSIONS : The female patients of PAOD presented with severe symptoms and advanced Fontaine stages . - pubmed
Management of cryptococcal meningitis with extremely high intracranial pressure in HIV - infected patients . - pubmed
CONCLUSION : Octreotide scintigraphy is useful in localizing occult carcinoid tumors and can be used in the follow - up of patients after successful removal of these tumors . - pubmed
We report on a 21 - year - old man who presented with left testicular swelling and pyogenic discharge from the scrotum . - pubmed
METHODS : We performed a prospective study of 13 patients with dermatochalasis who underwent radiosurgery in one upper eyelid and conventional surgery with scalpel and scissors in the contralateral eyelid . - pubmed
Psychostimulant - induced behavior as an animal model of obsessive - compulsive disorder : an ethological approach to the form of compulsive rituals . - pubmed
Moreover , in both quinpirole - treated rats and OCD patients , the structure of compulsive rituals appear similar in being composed of relatively few motor acts that are organized in a flexible yet recurrent manner . - pubmed
In addition , the development of compulsive behavior in quinpirole - treated rats is attenuated by the OCD pharmacotherapeutic drug clomipramine . - pubmed
These similarities support the validity of quinpirole - treated rats as a psychostimulant - induced animal model of OCD . - pubmed
Partial splenectomy is the preferred technique because of the short- and long - term sepsis problems in asplenic patients . - pubmed
CONCLUSION : Partial splenectomy was achieved in the ovine spleen using radiofrequency energy with minimal blood loss . - pubmed
SUBJECTS AND METHODS : A group of eight patients from the pulmonary clinic in Rabin Medical Center with a combine presentation of fibrosis and emphysema was identified retrospectively . - pubmed
RESULTS : Upper - lobe emphysema with bulluos changes was found in all patients . - pubmed
Most of the patients had moderate - to - severe pulmonary hypertension as well as diffuse coronary artery disease . - pubmed
The aim of this study was to assess the effect of thermal stimuli or distal scratching on skin blood flow and histamine - induced itch in healthy volunteers . - pubmed
Diagnostic value of gall bladder wall thickness in patients with ascites . - pubmed
A retrospective study was performed on 841 patients with endometrial cancer , who underwent the initial surgery at the Keio University Hospital . - pubmed
Among the 155 patients who underwent pelvic and para - aortic lymph node dissection , the difference of 5 - year overall survival by the presence of retroperitoneal lymph node metastasis was examined by Kaplan - Meier method . - pubmed
MATERIAL : 40 patients after spine surgery because of low back pain and 20 persons of control group participated in the study . - pubmed
Moreover , tumors collected from 40 dogs in 5 continents are derived from a single neoplastic clone that has diverged into two subclades . - pubmed
Phylogenetic analyses indicate that CTVT most likely originated from a wolf or an East Asian breed of dog between 200 and 2500 years ago . - pubmed
Photodynamic therapy of experimental choroidal neovascularization in the mouse . - pubmed
PURPOSE : To evaluate the qualitative and quantitative effects of verteporfin photodynamic therapy ( PDT ) on laser - induced choroidal neovascularization ( CNV ) in the mouse . - pubmed
However , PDT - treated areas will remain vascularized with continued growth of the CNV lesion , which in turn may explain the often limited effect of PDT in patients with neovascular age - related macular degeneration . - pubmed
MATERIAL AND METHODS : 15 patients with cystic fibrosis and 15 control subjects were included in this study . - pubmed
We report a 23 - year - old patient undergoing functionally univentricular repair who developed cardiac failure due primarily to systemic ventricular dysfunction . - pubmed
Aortic counterpulsation facilitates recovery of systemic ventricular function , and appears to be a reasonable alternative in select instances of cardiac failure in patients with the Fontan circulation . - pubmed
CA revealed CAD in 25 patients . - pubmed
MATERIALS AND METHODS : The charts of children diagnosed with PPU at our hospital from January 1986 to June 2005 were reviewed . - pubmed
Nine patients ( 17.3 % ) had postoperative complications . - pubmed
The summary risk ratio for contrast - related nephropathy was 0.69 ( 95 % confidence interval : 0.57 to 0.82 ; P = 0.02 ) , a statistically significant trend towards benefit in patients treated with N - acetylcysteine . - pubmed
Demographically adjusted normative standards were derived from a sample of 182 seronegative healthy participants and were subsequently applied to a sample of 135 HIV-1 seropositive individuals with multidisciplinary case conference diagnoses of HIV-1 - associated neurocognitive disorders ( e.g. - pubmed
Patients with multiple myeloma ( MM ) have increased bone marrow angiogenesis , but the angiogenic properties of myeloma cells and the mechanism of MM - induced angiogenesis have not been completely clarified . - pubmed
Finally , our in vitro results were supported by the in vivo finding in human myeloma xenograft NOD / SCID models . - pubmed
[ Parameters of hypothalamo - pituitary - adrenal , thyroid and genital systems in patients with occupational allergic dermatosis ] . - pubmed
This article describes the case of a patient who presented with an open , comminuted first metatarsal fracture as a result of a chainsaw injury . - pubmed
The patient was treated with a uniplanar mini - external fixator , demineralized bone matrix , primary wound closure , and external bone growth stimulation . - pubmed
Intravitreal bevacizumab ( avastin ) as a treatment for refractory macular edema in patients with uveitis : a pilot study . - pubmed
CONCLUSIONS : In uraemic rats with established secondary hyperparathyroidism , we demonstrate differential effects of paricalcitol and doxercalciferol on aortic calcification and PWV , independent of serum Ca , P and Ca x P , suggesting different mechanisms of action between VDRAs . - pubmed
Carbon monoxide poisoning in children . - pubmed
BACKGROUND : Carbon monoxide ( CO ) is an important source of poisoning in children . - pubmed
We performed this study in order to clarify the clinical characteristics of pediatric patients with CO poisoning . - pubmed
METHODS : We identified and reviewed the medical records of pediatric patients diagnosed with CO intoxication and hospitalized in our department during a 10 - year period . - pubmed
RESULTS : A total of 30 children with CO poisoning were identified . - pubmed
Seizures during the acute stage , severe metabolic acidosis , significant hypotension , longer times for recovery to full consciousness , and longer hospital stays were observed in children with DNS . - pubmed
CONCLUSION : Children with CO poisoning had good outcomes in this series . - pubmed
CONCLUSIONS : When used with socially anxious adolescents , VF may be a beneficial therapeutic technique in correcting a distorted self - perception of performance , reducing anxiety prior to entering a stressful social task and enhancing predictions of performance for future tasks . - pubmed
In order to clarify the role of Gnathostoma turgidum as an etiological agent involved in human gnathostomiasis in Mexico , establish the taxonomic identity of the advanced third - stage larvae ( AdvL(3 ) ) , and contribute to the knowledge of its life cycle , experimental host infections , examination of potential natural hosts , and morphological comparisons were carried out . - pubmed
129 / SV mice were subjected to 30 min filamentous middle cerebral artery occlusion ( MCAo ) , followed by reperfusion . - pubmed
The present study was designed to use stem cells preconditioned with trimetazidine ( 1 -[ 2,3,4 - trimethoxybenzyl ] piperazine ; TMZ ) , a widely used anti - ischemic drug for treating angina in cardiac patients , to increase the rate of their survival after transplantation . - pubmed
Bone marrow - derived rat mesenchymal stem cells ( MSCs ) were subjected to a simulated host tissue environment by culturing them under hypoxia ( 2 % O ( 2 ) ) and using hydrogen peroxide ( H ( 2 ) O ( 2 ) ) to induce oxidative stress . - pubmed
The therapeutic efficacy of the TMZ - preconditioned MSCs was evaluated in an in vivo rat model of myocardial infarction induced by permanent ligation of left anterior descending coronary artery . - pubmed
Acute light - induced photoreceptor degeneration has been studied in experimental animals as a model for photoreceptor cell loss in human retinal degenerative diseases . - pubmed
We investigated the hypothesis that various antidiabetic drugs had differential direct impact on cancer cells using four human cell lines ( pancreatic cancer : MiaPaCa2 , Panc-1 ; breast cancer : MCF7 , HER18 ) . - pubmed
This study provides experimental evidence to support further investigation of metformin and rosiglitazone as first - line therapies for type 2 diabetes in cancer patients . - pubmed
CUMS - induced depression model was established in Sprague - Dawley rats . - pubmed
The results showed that , compared with the control group , rats receiving CUMS for 21 d or intrahippocampal microinjection of GR231118 showed a significant reduction in body weight and depression - like behavior , which included reductions in sucrose preference , locomotor activity , rearing and grooming in open field test , and increased duration of immobility in forced swimming test . - pubmed
METHODS : In this prospective , correlational study , SbpO(2 ) , SaO(2 ) , and SpO ( 2 ) values were recorded at normoxemia and at three hypoxemic conditions ( SpO(2)=90 % , 80 % , and 70 % ) for 53 healthy , nonsmoking adults who were without cardiac or pulmonary disease , baseline hypoxemia , peripheral edema , dyshemoglobinemia , and fever . - pubmed
Transplantation of umbilical cord mesenchymal stem cells alleviates lupus nephritis in MRL / lpr mice . - pubmed
Systemic lupus erythematosus ( SLE ) is a multisystem autoimmune disease , which , despite the advances in immunosuppressive medical therapies , remains potentially fatal in some patients , especially in treatment - refractory patients . - pubmed
This study found that transplantation of umbilical cord mesenchymal stem cells ( UC - MSCs ) has the same therapeutic effect as transplantation of bone marrow mesenchymal stem cells ( BM - MSCs ) , which has been reported to be efficient in treating SLE - related symptoms in MRL / lpr mice . - pubmed
Multi - treatment ( at the 18th , 19th , and 20th weeks of age ) of 1 x 10(6 ) UC - MSCs was able to decrease the levels of 24 - h proteinuria , serum creatinine , and anti - double - stranded DNA ( dsDNA ) antibody , and the extent of renal injury such as crescent formation in MRL / lpr mice . - pubmed
When do asymmetrical full - field pattern reversal visual evoked potentials indicate visual pathway dysfunction in children ? - pubmed
In this study we perform laser - induced axotomy of the porcine retinal ganglion cell axon , a physiologically unmyelinated , mature CNS axon that is structurally similar to humans to infer knowledge about axonal behaviour in the absence of myelin . - pubmed
Filtrates of 57 staphylococci showed strong activity against Listeria monocytogenes Scott A , and 52 isolates also inhibited the growth of Stapylococcus aureus Newbould 305 , a major causative agent of bovine mastitis in the United States . - pubmed
Over the past 60 years , investigators of basic science , pathology , and clinical medicine have studied gastrointestinal stromal tumor ( GIST ) and made minor advances in patient care . - pubmed
Age - related changes in genomic stability of horses . - pubmed
Here , we show that breed - independent and age - associated changes in genomic stability may contribute , at least in part , to the aging process in the horse . - pubmed
We report the conjugation of the C - terminal alpha - helix of human melanoma growth stimulating activity to daunorubicin using the novel linker polyethylene glycol ( 3400 ) dialdehyde . - pubmed
METHODS : One hundred and sixty - three female pregnant kunming mice were randomly divided into 6 groups , including A , control group ; B , ovulation stimulation ( OS ) group ; C , OS+TCM group ; D , embryo implantation dysfunction ( EID ) group ; E , EID+TCM group ; F , TCM only group . - pubmed
A prospective study of fifty patients who underwent cataract surgery with intraocular lens ( IOL ) implantation was undertaken . - pubmed
We report a case of a 25 - year - old woman who presented with a small intestinal angiosarcoma associated with angiosarcomatosis . - pubmed
Instead of its usage when antegrade recanalization failed , the " facedown " technique was preferred as a first choice in patients with common femoral artery stenosis or occlusion , proximal lesions of the superficial femoral artery ( SFA ) with no stump , severe obesity , tandem iliac , and SFA lesions . - pubmed
Stapler access and visibility in the deep pelvis : A comparative human cadaver study between a computerized right angle linear cutter versus a curved cutting stapler . - pubmed
Noncontrast techniques for peripheral MR angiography are receiving renewed interest because of safety concerns about the use of gadolinium in patients with renal insufficiency . - pubmed
Persistent hyperglycemia at 24 - 48 h in acute hyperglycemic stroke patients is not associated with a worse functional outcome . - pubmed
METHODS : We analyzed all patients with glucose & gt;7.3 mmol / l on admission from the Acute STroke Registry and Analysis of Lausanne ( ASTRAL ) . - pubmed
RESULTS : A total of 1,984 patients with ischemic stroke were admitted between January 1 , 2003 and October 20 , 2009 , within 24 h after last well - being time . - pubmed
In multiple logistic regression analysis , unfavorable outcome was significantly associated with age ( odds ratio , OR : 1.06 , 95 % confidence interval , 95 % CI : 1.03 - 1.08 for every 10 - year increase ) , National Institute of Health Stroke Score , NIHSS score , on admission ( OR : 1.16 , 95 % CI : 1.11 - 1.21 ) , prehospital mRS ( OR : 12.63 , 95 % CI : 2.61 - 61.10 for patients with score & gt;0 ) , antidiabetic drug usage ( OR : 0.36 , 95 % CI : 0.15 - 0.86 ) and glucose on admission ( OR : 1.16 , 95 % CI : 1.02 - 1.31 for every 1 mmol / l increase ) . - pubmed
CONCLUSIONS : In ischemic stroke patients with acute hyperglycemia , persistent hyperglycemia ( & gt;7.3 mmol / l ) at 24 - 48 h after stroke onset is not associated with a worse functional outcome at 3 months whether the patient was previously diabetic or not . - pubmed
Originally discovered by McCay 's group in the 1930s , this paradigm showed that animals placed on the DR regimen , meaning reduced nutrition without malnutrition , had robust life extensions ( 1 ) . - pubmed
We present a rare case of combined fungal infection in a critically ill 47 year - old patient with chronic hepatitis C at the stage of liver cirrhosis . - pubmed
MATERIALS AND METHODS : 130 patients ( 87 male and 43 female ; age range 49 - 86 years , mean 71.1 ) were selected whose diagnoses were pathologically confirmed as CRC with schistosomiasis . - pubmed
Linear , spotty and small patchy calcifications were seen in 104 ( 80.0 % ) patients , with unclear margins in 96 patients . - pubmed
The tumors were markedly unevenly enhanced in 92 patients . - pubmed
Pathological examination revealed adenocarcinoma in 114 patients and in 104 patients , calcified Shistosoma japonicum ( S. - pubmed
japonicum ) ova inside the tumors , 15 patients were mucinous adenocarcinoma , and one patient was that of adenosquamous carcinoma . - pubmed
We report a 4 - year - old girl presenting with sudden severe bilateral visual loss . - pubmed
Studying the effect of IBD susceptiblity gene dysfunctions in tissue cultures and animal models will allow the ultimate translational benefits of developing novel treatments for and potentially preventing IBD in those having specific genetic risk factors . - pubmed
Electrophysiological and motor function scale association in a pre - symptomatic infant with spinal muscular atrophy type I. - pubmed
There was no significant effect of individual GM6 and KM genotypes on the risk of PM infection in HIV-1 negative and positive women . - pubmed
However , the combination of homozygosity for GM6(+ ) and KM3 was associated with decreased risk of PM ( adjusted OR , 0.25 ; 95 % CI , 0.08 - 0.8 ; P = 0.019 ) in HIV-1 negative women while in HIV-1 positive women the combination of GM6(+/- ) with either KM1 - 3 or KM1 was associated with increased risk of PM infection ( adjusted OR , 2.10 ; 95 % CI , 1.18 - 3.73 ; P = 0.011 ) . - pubmed
These findings suggest that the combination of homozygous GM6(+ ) and KM3 may protect against PM in HIV-1 negative women while the HIV-1 positive women with heterozygous GM6(+/- ) combined with KM1 - 3 or KM1 may be more susceptible to PM infection . - pubmed
Breaking Barriers to an AIDS Model with Macaque - Tropic HIV-1 Derivatives . - pubmed
The development of an animal model of human immunodeficiency virus type 1 ( HIV-1 )/ AIDS that is suitable for preclinical testing of antiretroviral therapy , vaccines , curative strategies , and studies of pathogenesis has been hampered by the human - specific tropism of HIV-1 . - pubmed
In this review , we discuss recent findings regarding HIV-1 restriction factors , particularly as they apply to cross - species transmission of primate lentiviruses and the development of a macaque model of HIV-1 / AIDS . - pubmed
The prognostic role of late gadolinium enhancement magnetic resonance imaging in patients with cardiomyopathy . - pubmed
Cardiovascular magnetic resonance imaging ( CMRI ) is currently considered part of standard care at many academic centres for the evaluation of patients with ischemic or nonischemic cardiomyopathy . - pubmed
Given the low specificity of currently available clinical markers in patients with cardiomyopathy , more - robust biomarkers aimed at identifying those at high risk of sudden cardiac death and other relevant outcomes are desirable . - pubmed
This review paper focuses on the evidence to date supporting LGE imaging as a tool for the prediction of future cardiovascular events in patients with ischemic and nonischemic cardiomyopathy . - pubmed
CASE DESCRIPTION : A 44 - year - old male presented with complaints of left - sided retro - orbital pain , double vision , and numbness over the upper face and scalp on the left side of 1 - week duration . - pubmed
OBJECTIVE : Extracts from 16 plants identified and selected from the ethnomedicine of the Ijebus in Southwestern Nigeria as remedies for tuberculosis were evaluated for activity against Mycobacterium tuberculosis , in vitro . - pubmed
PURPOSE OF REVIEW : In multiple sclerosis ( MS ) , symptoms vary widely from patient to patient . - pubmed
Furthermore , following administration of APP96 - 110 in rats after diffuse impact acceleration TBI , motor and cognitive outcomes were significantly improved and axonal injury reduced . - pubmed
Renal denervation prevents stroke and brain injury via attenuation of oxidative stress in hypertensive rats . - pubmed
Sipuleucel - T is an antigen - presenting cell - based active immunotherapy that utilizes a patient 's own immune cells , presumably to activate an antigen - specific immune response against tumor cells . - pubmed
METHODS : A retrospective cohort study was performed to include pediatric patients presenting with headache fulfilling the International Classification of Headache Disorders-2 migraine criteria in a tertiary care ( site 1 ) and a community based ( site 2 ) emergency department . - pubmed
[ Management of Fournier ' s gangrene in HIV - positive patients : report of 29 cases ] . - pubmed
OBJECTIVE : To review the clinical characteristics and treatment strategies of Fournier ' s gangrene in HIV - positive patients . - pubmed
METHODS : We retrospectively analyzed the clinical characteristics and therapeutic methods of 29 HIV - positive cases of Fournier ' s gangrene . - pubmed
The two aged patients were complicated by diabetes mellitus . - pubmed
Twenty - six of the patients were recovered and the other 3 ( 10.3 % ) died after surgery , 1 from infectious shock and 2 from diabetes mellitus complicated by pulmonary infection and renal failure . - pubmed
CONCLUSION : Timely aggressive surgical debridement , incision - drainage and broad - spectrum antibiotic medication are essential for the treatment of Fournier ' s gangrene in HIV - positive patients . - pubmed
We also investigated the effects of these drug combinations on tumor growth in a nude mouse xenograft model . - pubmed
Finally , treating mice - bearing RMG - I with AZD7762 and cisplatin significantly suppressed growth of tumors in a xenograft model . - pubmed
CONCLUSIONS : The present study indicates that chemotherapy with AZD7762 and cisplatin should be explored as a treatment modality for women with ovarian clear cell carcinoma . - pubmed
NMD modulates the clinical outcome of a variety of human diseases , including cancer and many genetic disorders , and may represent a target for therapeutic intervention . - pubmed
RESULTS : Number of patients who developed sore throat was significantly higher in the Succinylcholine group ( 75 % ) compared to Cisatracurium group ( 27.5 % ) at the time of entrance to the recovery room ( P = 0.001 ) . - pubmed
RESULTS : The study included 2679 CAC and 1135 Reference patients . - pubmed
Here , we review the various phenotypic traits that have been proposed to be affected by the highly parasitic human environment , including fertility , birth weight , fluctuating asymmetry , body odours , food recipes , sexual behaviour , pregnancy sickness , language , religion and intellectual quotient . - pubmed
Technique selection should be tailored to each individual case on the basis of tumour characteristics , surgical feasibility , surgeon experience , patient demographics and baseline renal function . - pubmed
WITHDRAWN : Superoxide generation in different brain regions of rats during normoxia and hypoxia - reoxygenation . - pubmed
Staphylococcus aureus induces hypoxia and cellular damage in porcine dermal explants . - pubmed
Predominant bands related to lactic acid bacteria , such as Lactococcus and Lactobacillus strains , were sequenced from the DGGE patterns of fish fed the probiotic diet , whereas they were not sequenced from fish receiving the control diet . - pubmed
Functionally , the effects of D+I were tested in glaucomatous rats . - pubmed
BACKGROUND : GAMT deficiency is an autosomal recessive disorder of creatine biosynthesis causing developmental delays or intellectual disability in untreated patients as a result of irreversible brain damage occurring prior to diagnosis . - pubmed
The newborn screening for GAMT deficiency should be implemented to identify patients at the asymptomatic stage to achieve normal neurodevelopmental outcome for this treatable neurometabolic disease . - pubmed
Patients with & gt;10 coronal curves , significant sagittal malalignment , infection , and preoperative instrumentation failure were excluded . - pubmed
Complications included asymptomatic cage migration alone ( two patients ) neurological decline ( two patients ) and epidural hematoma ( one patient ) . - pubmed
CONCLUSIONS : The major new finding from this study is that HHcy induced a marked increase in PE - induced contraction in rat corpus cavernosum by a mechanism that involves increased O2 (- ) generation and it could play a role in the pathogenesis of erectile dysfunction associated with HHcy . - pubmed
A prospective observational study was conducted to correlate EUS evaluation of paraesophageal varices , azygos vein , and thoracic duct with variceal recurrence after EBL variceal eradication in patients with cirrhosis . - pubmed
Seventeen patients ( 57 % ) presented variceal recurrence . - pubmed
The emergence of Mycobacterium tuberculosis strains that are resistant to the current anti - tuberculosis ( TB ) drugs necessitates a need to develop a new class of drugs whose targets are different from the current ones . - pubmed
The equilibrium between the ventricular and lumbar cerebrospinal fluid ( CSF ) compartments may be disturbed ( in terms of flow and biochemistry ) in patients with chronic hydrocephalus ( CH ) . - pubmed
OBJECTIVE : Recent studies have demonstrated improved outcomes in patients receiving early surgery for degenerative mitral regurgitation ( MR ) rather than adhering to conventional guidelines for surgical intervention . - pubmed
METHODS : One hundred and fifty - one patients with unilateral osteonecrosis of the femoral head were enrolled consecutively for current prospective study from January to August of 2006 . - pubmed
Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates Rotenone Induced Neurotoxicity in Cell and Drosophila Models of Parkinson ' s Disease . - pubmed
Based on these data , we surmise that CMG has improved bioavailability and offered neuroprotection comparable with CUR , against ROT - induced toxicity both in dopaminergic neuronal cell line and Drosophila models , with therapeutic implications for PD . - pubmed
Traditionally , myeloid - derived suppressor cells ( MDSC ) have been studied in regard to their increased numbers of circulating cells in cancer patients . - pubmed
The expanded population of DC - HIL(+ ) Mo - MDSC in psoriasis patients , however , display inferior suppressive capabilities compared to DC - HIL(+ ) Mo - MDSC found in melanoma patients , suggesting contextual signaling as a potential contributing factor to Mo - MDSC function . - pubmed
METHOD AND RESULTS : A 44 - year - old man was admitted due to severe epigastric pain . - pubmed
The patient was diagnosed with non - small cell lung cancer 9 months ago and received 6 cycles of chemotherapy with motesanib , paclitaxel , and carboplatin . - pubmed
The synthetic BSeDs were identified as potent antiproliferative agents against the human MCF-7 and MDA - MB-231 breast cancer cell lines . - pubmed
HIV-1 promotes a generalized immune activation that involves the main targets of HIV-1 infection but also cells that are not sensitive to viral infection . - pubmed
In vivo studies have failed to demonstrate the presence of replicating virus in ECs suggesting that a direct role of the virus is unlikely , and implying that the mechanism accounting for vascular dysfunction may rely on the indirect action of molecules released in the microenvironment by HIV-1 - infected cells . - pubmed
In particular , we discuss the emerging role played by different HIV-1 proteins in driving inflammation and EC dysregulation , and highlight the need to target them for therapeutic benefit . - pubmed
The results demonstrate the larval zebrafish model as a useful tool in the study of intrinsic cardiac activity and its role in heart diseases . - pubmed
Therefore the aim of the present work was to investigate the effects of SMF on autonomic cardiovascular control in adult spontaneously hypertensive rats . - pubmed
MATERIALS AND METHODS : Experiments were performed in freely moving spontaneously hypertensive rats equipped with femoral arterial catheter for blood pressure recording . - pubmed
A control group of spontaneously hypertensive rats ( n = 17 ) was not exposed to SMF . - pubmed
The aim of this study is to investigate overweight , as a predictor of brace results in AIS patients . - pubmed
Influence of the Valsalva maneuver on cardiac hemodynamics and right to left shunt in patients with patent foramen ovale . - pubmed
The purpose of this study was to investigate the influence of the Valsalva maneuver ( VM ) on cardiac hemodynamics in patients with patent foramen ovale ( PFO ) . - pubmed
Sixty - five patients who were highly suspected to have PFO were included . - pubmed
The results showed that JA - treated sugarcane did not affect the weight gain of the two larvae . - pubmed
Here , using the pooling sequencing - based methodology , we deciphered the genetic basis for the varied silk production in different silkworm strains . - pubmed
A Profile of Individuals with Anti - tobacco Message Fatigue . - pubmed
OBJECTIVES : Message fatigue , a phenomenon of being tired of repeated exposure to messages promoting the same health behavior , may reduce the effectiveness of anti - tobacco messages , such as warning labels . - pubmed
METHODS : Liver Fibrosis was induced in mice by carbon tetrachloride ( CCl4 ) . - pubmed
Immunohistochemical staining using tissue microarray with 312 samples from randomly selected patients with HCC who underwent surgery . - pubmed
The neurorestorative effect of human amniotic fluid stem cells on the chronic phase of neonatal hypoxic - ischemic encephalopathy in mice . - pubmed
However , the efficacy of human amniotic fluid stem cells ( hAFS ) for HIE , especially in the chronic phase , remains unclear . - pubmed
HI was induced in 9 - day - old mice . - pubmed
CONCLUSION : hAFS induced functional recovery by exerting neurorestorative effects in HIE mice , suggesting that intranasal administration of hAFS could be a novel treatment for HIE , especially in the chronic phase . - pubmed
Patients were classified based on the coexisting liver disease at the time of HF , ie , no liver disease , noncirrhotic liver disease , and liver cirrhosis . - pubmed
Results : Among 152,180 HF patients , 2,552 ( 1.7 % ) patients had noncirrhotic liver disease and 1,866 ( 1.2 % ) patients had liver cirrhosis . - pubmed
Thirty - day mortality was 9.4 % among patients with noncirrhotic liver disease , 12.6 % among patients with liver cirrhosis patients , and 9.7 % among patients without liver disease . - pubmed
Conclusion : Liver disease patients , especially those with liver cirrhosis , had increased 30 - day mortality and 31 - 365 - day mortality following HF , compared to patients without liver disease . - pubmed
However , there are also various concerns or limitations over the use of natural materials derived from animals or cadavers , including the potential immunogenicity , pathogen transmission , batch to batch consistence and mismatch in properties for various applications . - pubmed
METHODS : We analyzed SCFA levels by high - performance liquid chromatography ( HPLC ) in fecal samples from 301 one - year - old children from a birth cohort and examined their association with early life exposures , especially diet , and allergy and asthma later in life . - pubmed
In addition , we treated mice with SCFAs to examine their effect on allergic airway inflammation . - pubmed
Children with the highest levels of butyrate and propionate ( & gt;=95th percentile ) in feces at the age of one year had significantly less atopic sensitization and were less likely to have asthma between 3 and 6 years . - pubmed
Children with the highest levels of butyrate were also less likely to have a reported diagnosis of food allergy or allergic rhinitis . - pubmed
Oral administration of SCFAs to mice significantly reduced the severity of allergic airway inflammation . - pubmed
CONCLUSION : Our results suggest that strategies to increase SCFA levels could be a new dietary preventive option for allergic diseases in children . - pubmed
Frosty pod rot ( FPR ) disease on cocoa , caused by Moniliophthora roreri , is one of the most devastating cocoa disease in the Western Hemisphere . - pubmed
Insulin resistance : a key therapeutic target for cardiovascular risk reduction in obese patients ? - pubmed
As clinical studies suggest that insulin resistance may play a key role in the cardiovascular benefit achieved with weight loss intervention , we will discuss our clinical perspective and provide evidence that obese individuals with hyperinsulinemia may derive the greatest improvement in vascular function with weight reduction . - pubmed
MR findings of uterine PEComa in patients with tuberous sclerosis : report of two cases . - pubmed
Today , increased attention has been focused on PML development in multiple sclerosis ( MS ) patients under disease - modifying therapies ( DMT ) . - pubmed
Our study was performed in a population of 234 patients with type 2 diabetes mellitus ( T2DM ) and 78 healthy subjects . - pubmed
Pupose : To experimentally compare the visual acuity and the subjective perception of different types of multifocal intraocular lenses ( IOL ) using a VirtIOL device / simulator in a group of volunteers with artephakia . - pubmed
MATERIAL AND METHODS : This was an experimental study involving a total of 20 volunteers with artephakia ( 35 eyes ) . - pubmed
Each volunteer rated 5 types of IOLs , 4 presbyopia - correcting IOLs - WIOL - CF , Tecnis Symphony ZXR00 , Acrysof IQ PanOptix TFNT00 , M - flex 630 F , and as a reference lens , we used the monofocal IOL Acrysof SA60AT . - pubmed
Conclusions : The patients in the non - PPI group were observed to be associated with less risk of MACE , myocardial infarction recurrence , stent thrombosis , target vessel revascularization ( TVR ) and stroke . - pubmed
Potential clinical aims in imaging patients with CAAs may be primary screening , severity evaluation , preoperative planning , and postoperative follow - up . - pubmed
Rarely , IVUS may be needed in patients with potentially serious CAAs and has unique advantages and limitations . - pubmed
In adolescents or adults , intramural course of an anomalous coronary artery is the only important feature accompanied by stenosis of potential severity and is especially relevant in patients with a high - risk status ( elite sport athletes , military recruits ) . - pubmed
OBJECTIVE : To review the etiology and clinical manifestations of severe cutaneous adverse reactions ( SCARs ) and the demographic characteristics of patients with SCARs . - pubmed
METHODS : This study is a retrospective review of electronic medical records for patients who developed drug - induced cutaneous reactions and were treated for initial or ongoing care at a university medical center from June 4 , 2008 , to August 10 , 2018 . - pubmed
Most of the patients with SCARs were given triamcinolone cream and prednisone alone ( 18 [ 51.4 % ] ) , methylprednisolone alone ( 1 [ 2.9 % ] ) , methylprednisolone and prednisone combined ( 4 [ 11.4 % ] ) , methylprednisolone and prednisolone ( 1 [ 2.9 % ] ) or prednisone and prednisolone ( 1 [ 2.9 % ] ) . - pubmed
Among 5028 patients with HF and reduced ejection fraction ( HFrEF ; EF & lt;40 % ) and 1139 patients with HF and preserved EF ( HFpEF ; EF & gt;=50 % ) , the prevalences of type 2 diabetes mellitus were 40.2 % and 45.0 % , respectively ( P=0.003 ) . - pubmed
Emesis castigata diringeri Gallard 2008 is a subjective junior synonym of E. - pubmed
NK cells represent 10 - 20 % of total lymphocytes in the peripheral blood of humans and play an essential role in clearing infections and malignant cells . - pubmed
Alternatively , considering our REE findings in adult 21 - OH CAH patients , nutrition management based on 25 kcal / body weight / day ( measured REE * activity factor 1.2 - 1.3 ) may be reasonable for current body weight maintenance in these patients . - pubmed
Urolithiasis in Children . - pubmed
Outcome in patients with isolated regional recurrence after primary radiotherapy for head and neck cancer . - pubmed
Factors prognostic for outcome were investigated in a large cohort of HNSCC patients . - pubmed
No - reflow phenomenon ( NRP ) is an important problem in patients with ST - segment elevation myocardial infarction ( STEMI ) undergoing primary percutaneous coronary intervention ( pPCI ) . - pubmed
Consecutive patients ( n = 137 ) with STEMI who had undergone coronary angiography and pPCI were enrolled into the study . - pubmed
An 18 - year - old man showed swelling , pain , and limited motion of the hand , knee , and foot joints without X - ray abnormalities at 2 years old ( X-16 ) . - pubmed
Morphology of the cisterna chyli in nine dogs with idiopathic chylothorax and in six healthy dogs assessed by computed tomographic lymphangiography . - pubmed
OBJECTIVE : To describe the morphology of the lymphatics in the region of the cisterna chyli in healthy dogs and in dogs with idiopathic chylothorax by using computed tomographic lymphangiography . - pubmed
ANIMALS : Nine dogs with idiopathic chylothorax and six healthy dogs . - pubmed
Data ( mean + - SD ) were compared between unaffected dogs and dogs with idiopathic chylothorax . - pubmed
RESULTS : The cisterna chyli included more branches in dogs with chylothorax ( 4.30 + - 1.57 ) than in unaffected dogs ( 1.67 + - 0.56 , P = .02 ) , occupying a relative perimeter approximately double that in unaffected dogs ( P < .001 ) . - pubmed
CONCLUSION : The cisterna chyli of dogs with idiopathic chylothorax contained smaller and more numerous branches compared with that of unaffected dogs . - pubmed
CLINICAL SIGNIFICANCE : Altered cisterna chyli morphology may impact the surgical approach for cisterna chyli ablation in dogs with idiopathic chylothorax . - pubmed
Overall , successful management of MTC patients heavily relies on the patient 's conditions , tumor stage , genetic background , and the medical team 's experience . - pubmed
Forty patients were surgically treated for lateral pain- ful instability of the ankle . - pubmed
We recruited 12 068 patients with AF ( 6034 patients in each cohort ) . - pubmed
The performance of hepatitis C virus ( HCV ) antibody point - of - care tests on oral fluid or whole blood and dried blood spot testing for HCV serology and viral load among individuals at higher risk for HCV in South Africa . - pubmed
Degradation of benzo [ a ] pyrene by halophilic bacterial strain Staphylococcus haemoliticus strain 10SBZ1A. - pubmed
A 62 - year - old man developed a recurrent keratoacanthoma within two and a half weeks after grossly and microscopically complete removal of the primary tumor . - pubmed
The importance of uropathogenic Escherichia coli in causing acute and recurrent pyelonephritis with the consequent morbidity of chronic renal failure is well established . - pubmed
Pyelonephritis - associated ( Pap ) pili are likely to be critical virulence factors in uropathogenic E. - pubmed
HIV / AIDS . - pubmed
Heel erosion and other interdigital disorders in dairy cows : associations with season , cow characteristics , disease , and production . - pubmed
Epidemiologic associations between variables obtainable from dairy cow records and the occurrence of heel erosion , interdigital dermatitis , and interdigital hyperplasia at claw trimmings were estimated with multivariable logistic regression analysis on data from 1170 and 542 cows in lactation 1 and lactations 2 to 9 , respectively . - pubmed
In the 17 herds , heel erosion , interdigital dermatitis , and hyperplasia occurred among 43.8 , 4.5 , and .9 % of cows in lactation 1 and among 69.1 , 7.6 and 5.9 % of cows in lactations 2 to 9 , respectively . - pubmed
In the present study , although considerable intersubject variability was observed , several subjects exhibited deficits on the brief tone frequency difference limen test similar to that observed with temporal lobe lesion patients , but present at both ears . - pubmed
Suppression by beta - carotene - rich algae Dunaliella bardawil of the progression , but not the development , of spontaneous mammary tumours in SHN virgin mice . - pubmed
A high mammary tumour strain of SHN virgin mice were given vitamin A deficient AIN-76TM diet supplemented with D. - pubmed
bardawil maintained the levels of non - tumorous mice even after the development of tumours . - pubmed
bardawil can inhibit the progression of spontaneous mammary tumours of mice by increasing the homeostatic potential of the host animals as well as by the well - known antioxidant function of beta - carotene in D. - pubmed
The typical radiologic finding of a " non - ossifying fibroma " of the distal femoral metaphysis was seen in a 17 - year - old female patient with pain in the distal femur . - pubmed
Infectious crystalline keratopathy caused by Mycobacterium fortuitum and Pseudomonas aeruginosa . - pubmed
We have characterized autoantibodies that are directed against this particle from two patients with rheumatic diseases . - pubmed
Plasma volume expansion and PEEP in a canine model of acute Pseudomonas pneumonia . - pubmed
Four groups of anesthetized , ventilated dogs ( n = 6 in each group ) inoculated endotracheally with Pseudomonas aeruginosa were studied over 5 h as bilateral , hemorrhagic pneumonia developed . - pubmed
Cervical cultures of 2013 consecutive obstetric patients with no history of genital herpes simplex virus infection were used to determine the frequency of asymptomatic herpes simplex virus shedding in labor . - pubmed
Transient problems , such as pain or penile edema lasting longer than 4 weeks , occur in 10 to 15 per cent of patients , and serious complications such as infection or prosthesis erosion occur in 1 to 5 per cent . - pubmed
[ Effect of the administration of killed Lactobacillus acidophilus on the survival of suckling mice infected with a strain of enterotoxigenic Escherichia coli ] . - pubmed
The response of canine platelets to arachidonic acid ( AA ) stimulation was studied as a predictor of thrombotic potential . - pubmed
Group I ( control ) dogs whose platelets aggregated in response to AA stimulation had significantly higher 24 - hour platelet deposition ( % IE ) on the luminal surface of implanted grafts ( p less than 0.02 ) , lower 4 - week graft patency ( p less than 0.002 ) , and higher plasma TxB2 levels ( p less than 0.01 ) than those dogs whose platelets did not aggregate . - pubmed
There is evidence suggesting a correlation between Epstein - Barr virus ( EBV ) and the high incidence of lymphomas , and the most plausible explanation for this is the ability for EBV to cause ongoing B cell proliferation . - pubmed
Animals bearing subcutaneous Lewis lung tumors ( 50 - 100 mm3 ) were treated with a single dose of Fluosol - DA followed by 1 h of breathing carbogen or maintenance in air . - pubmed
A sixty - one - year - old woman developed acquired infundibular pulmonary stenosis eleven years after radiation therapy to the mediastinum . - pubmed
This study was undertaken to detect diagnostic ultrastructural changes in the alveolar walls in biopsies of patients with primary pulmonary hypertension ( PPH ) . - pubmed
By light microscopy 4 patients were diagnosed as having plexogenic pulmonary arteriopathy , 2 thromboembolic arteriopathy and 2 veno - occlusive ( PVOD ) disease . - pubmed
In 4 patients the diagnosis of PPH was further confirmed at autopsy . - pubmed
These consisted in marked thickening and duplication of the basement membrane of alveolar capillaries in the 4 patients with the plexogenic form of pulmonary hypertension . - pubmed
Patients with PVOD instead showed uniform thickening of the basement membrane . - pubmed
No changes were detected in the 2 biopsies of patients with the thromboembolic form of PPH . - pubmed
We conclude that ultrastructural studies contribute significantly to the precise characterization of pathologic changes in the lungs of patients with PPH . - pubmed
[ Cell populations of transplantable murine tumors of various degrees of histogenesis during their proliferation in the anterior chamber ] . - pubmed
N = 66 children ( none with an acute indication for surgery ) were observed immediately before premedication and again immediately before anaesthetization ; the anxiety of the children was scaled on 8 rating - scales . - pubmed
A foot and mouth disease syndrome in pigs caused by an enterovirus . - pubmed
[ Pathogenesis of cotton - wool spots . - pubmed
Among the 69 Proteus mirabilis strains studied , 75 % contained Tn7 , although none of these strains transferred trimethoprim resistance in conjugation tests . - pubmed
In a double - blind controlled study lasting 8 weeks , 50 anxious psychoneurotic outpatients with a primary diagnosis of generalized anxiety or panic disorder were randomly assigned to alprazolam ( n=30 ) , a new benzodiazepine , or placebo ( n=20 ) , after a washout period of 1 week . - pubmed
The epidemiological studies were designed to examine for associations between human leukemia and a rural environment , cattle farming , veterinary activities , or bovine leukosis . - pubmed
The serological studies were used to test serum samples from human cancer patients and from persons with potential occupational exposure to BLV , among others , for evidence of BLV antibodies . - pubmed
[ Problems in hypertension therapy in patients with a constant frequency pacemaker ] . - pubmed
Frozen and thawed prisms from three human neocortical specimens showed a similar degree of protection from freeze - thaw injury . - pubmed
High dose barbiturates were used to treat intracranial hypertension in 15 patients with nontraumatic brain lesions ; ( 3 hypertensive hemorrhage , 4 subarachnoid hemorrhage , 5 infarction , 2 global anoxia - ischemia and 2 encephalitis ) . - pubmed
Survival of the 5 patients with persistently lowered ICP and death of the remaining 10 may indicate an improvement in outcome attributable to the addition of high dose barbiturates to conventional therapy in non - traumatic brain swelling . - pubmed
Because of the resources required for their prolonged use , randomized studied in patients with intracranial hypertension are required to determine the effect of barbiturates on outcome . - pubmed
[ Changes in the mechanisms of respiration and cardiovascular function in bronchoconstriction caused by cigarette smoke and anaphylaxis in rabbits ] . - pubmed
Human in vivo evidence for trigeminovascular activation in cluster headache . - pubmed
In this study patients with episodic cluster headache fulfilling the criteria of the International Headache Society were examined during an acute spontaneous attack of headache to determine the local cranial release of neuropeptides . - pubmed
These data demonstrate for the first time in vivo human evidence for activation of the trigeminovascular system and the cranial parasympathetic nervous system in an acute attack of cluster headache . - pubmed
OBJECTIVE : The aim of the present study was to determine the accuracy of clinical diagnoses of dementia in a large group of patients evaluated in a multicenter , university - based , Alzheimer ' s disease diagnostic and treatment program . - pubmed
RESULTS : When diagnoses of probable Alzheimer ' s disease , possible Alzheimer ' s disease , and Alzheimer ' s disease plus another condition were combined , 163 ( 83 % ) of the patients were clinically regarded as likely to have had Alzheimer ' s disease . - pubmed
Of those patients , 134 ( 82 % ) were found to have neuropathological changes diagnostic of Alzheimer ' s disease or Alzheimer ' s disease plus another condition . - pubmed
A total of 116 patients were diagnosed as having probable Alzheimer ' s disease ; 100 ( 86 % ) of those were found to have pathological diagnoses of Alzheimer ' s disease or Alzheimer ' s disease plus another condition . - pubmed
Cerebral infarcts were found in 17 % of the patients clinically diagnosed with probable Alzheimer ' s disease . - pubmed
Lewy bodies with variable Alzheimer ' s disease - type pathological changes were found in 7 % of the patients with clinical diagnoses of probable Alzheimer ' s disease . - pubmed
Conversely , significant Alzheimer ' s disease - type pathological changes were found in 55 % of the patients clinically diagnosed as having vascular dementia . - pubmed
CONCLUSIONS : Clinicians accurately predict Alzheimer ' s disease - type neuropathological findings in a high proportion of cases of dementia but may not predict cerebrovascular pathology and Lewy bodies in some patients with apparent clinical Alzheimer ' s disease and may often fail to predict Alzheimer ' s disease - type pathological findings in patients with apparent vascular dementia . - pubmed
The influence of zinc supplementation on ethanol - induced embryopathy was studied by the simultaneous administration of ethanol and zinc to pregnant SD rats from gestational day 6 through 12 . - pubmed
Catheter obstruction occurred in one patient ( case 2 ) . - pubmed
Inhalation of vapor from black pepper extract reduces smoking withdrawal symptoms . - pubmed
We have studied patients with supraventricular arrhythmias , especially those suffering from the Wolff - Parkinson - White ( WPW ) syndrome . - pubmed
Magnetocardiographic localization of the preexcitation site was performed in 26 WPW patients , with an average accuracy of 2 + /- 1 cm in comparison to the results obtained by invasive catheter mapping . - pubmed
In addition , the level of conduction block was successfully determined in six patients with third - degree congenital atrioventricular block . - pubmed
The protective effect of folic acid supplementation has been demonstrated in patients at risk of neural tube defects by a large , randomized double - blind study . - pubmed
Moreover , the plasma level of conjugated dopamine in patients with essential hypertension was higher than that in control subjects , and being highest in patients with renal hypertension . - pubmed
The prevalence and specificity of these antibodies was studied in a French series of 285 patients with PBC and 497 control individuals affected with other liver or autoimmune diseases . - pubmed
At all ratios tested , AMs from patients with FL did not suppress the lymphoproliferation but instead had an enhancing effect . - pubmed
In conclusion , a defect in the ability of alveolar macrophages to suppress the proliferation of lymphocytes in the lung of patients with farmer 's lung is a major factor accounting for the development of the observed lymphocytic alveolitis . - pubmed
VLPs of human papillomavirus ( HPV ) are therefore the most promising vaccine candidate to prevent infections with HPVs associated with cervical cancer , the most frequent carcinoma in women worldwide . - pubmed
METHODS : A total of 32 patients who had undergone resection for colorectal carcinoma were followed for a median period of 24 months ( range , 6 - 36 months ) . - pubmed
Twenty - one patients ( Group 1 ) had no signs of recurrence , whereas the remaining 11 ( Group 2 ) developed hepatic ( n = 7 ) or pulmonary ( n = 4 ) metastases . - pubmed
The risk of perinatal transmission of hepatitis C virus ( HCV ) from a cohort of 95 human immunodeficiency virus ( HIV )- negative intravenous drug users ( IVDU ) is described , 89 of whom were positive for antibodies to HCV ( anti - HCV ) . - pubmed
Infection , defined as the presence of HCV RNA in a serum sample collected from an infant at any time during follow - up , was detected in six of 63 ( 9.5 % ) infants born to HCV antibody - positive viraemic mothers . - pubmed
Two of the six HCV - infected infants became HCV RNA negative during follow - up by 27 and 29 months . - pubmed
No difference was found between mothers who transmitted HCV to their infants and those who did not for HCV genotype , duration of drug use , duration of methadone use , methadone dose , history of alcohol abuse , past hepatitis B virus ( HBV ) infection , mode of delivery , maternal and gestational age , birth weight and incidence of breast - feeding . - pubmed
Mothers who transmitted HCV to their infants had a longer duration between membrane rupture and delivery than the mothers who did not transmit ( P = 0.03 ) . - pubmed
pylori in a prospectively investigated population of patients with corpus - predominant atrophic gastritis . - pubmed
PATIENTS AND METHODS : A consecutive series of 67 newly diagnosed cases of atrophic body gastritis was derived from a screening of 326 patients with unexplained anemia or dyspepsia . - pubmed
In all 67 patients , H. pylori infection was evaluated independently by histological assay and urease test . - pubmed
pylori infection , a potential cause of oxyntic gland atrophy , is found in one - fourth of patients with newly diagnosed atrophic body gastritis . - pubmed
Anaerobic degradation of alpha - resorcylate ( 3,5 - dihydroxybenzoate ) was studied with the denitrifying strain AR-1 , which was assigned to the described species Thauera aromatica . - pubmed
We studied clinical aspects of attention in three groups : children with developmental right - hemisphere syndrome and attention - deficit hyperactivity disorder ( ADHD ) , children with ADHD only , and normal controls . - pubmed
A high proportion of patients with hyperemesis gravidarum , about one - third to two - thirds in different series , have evidence of increased thyroid function . - pubmed
Only a small proportion of these patients have clinical hyperthyroidism , termed gestational thyrotoxicosis . - pubmed
Independent risk factor for long - term prognosis after myocardial infarction even in nondiabetic patients . - pubmed
OBJECTIVE : To investigate whether a relationship exists between admission plasma glucose level and long - term outcome in nondiabetic patients after an acute myocardial infarction . - pubmed
RESEARCH DESIGN AND METHODS : This was a retrospective study with prospective follow - up of 197 consecutive nondiabetic patients with acute myocardial infarction followed for 1.5 - 2.5 years at the Department of Cardiology at Karolinska Hospital . - pubmed
RESULTS : The mean admission plasma glucose level was 8.15 + /- 3.0 mmol / l. During follow - up , 60 ( 30 % ) patients died , 20 ( 10 % ) were rehospitalized for heart failure , 12 ( 6 % ) were rehospitalized for nonfatal reinfarction , and 79 ( 40 % ) had at least one of these events . - pubmed
CONCLUSIONS : Admission plasma glucose level in nondiabetic patients with acute myocardial infarction seems to be an independent predictor of long - term outcome . - pubmed
A 64 - year - old man with Cushing ' s syndrome and a pancreatic mass . - pubmed
Since plasmapheresis can reverse clinical symptoms , it early recognition and the measurement of serum viscosity is essential in patients suffering from diseases that may lead to this syndrome , and who develop psychiatric symptoms . - pubmed
Pericarditis after allogeneic peripheral blood stem cell transplantation caused by Legionella pneumophila ( non - serogroup 1 ) . - pubmed
A case of Legionella pericarditis caused by a Legionella pneumophila isolate other than serogroup 1 is reported in a 59 - year - old man after allogeneic peripheral blood stem cell transplantation . - pubmed
The patient 's clinical condition improved dramatically after treatment with clarithromycin and an echocardiography revealed the total disappearance of the pericardial effusion . - pubmed
We studied the clinicopathologic features of 36 patients with concurrent angiomyolipoma and renal - cell neoplasia from the consultation and surgical pathology files of nine institutions . - pubmed
Twenty - five sporadic cases of patients with angiomyolipoma and renal - cell neoplasia and 11 cases of patients with tuberous sclerosis , as defined by Gomez ' criteria , had mean ages of 59 and 53 years , respectively , and female - male ratios of 2:1 and 5:1 , respectively . - pubmed
The mean size of the angiomyolipomas was 1 cm in the sporadic cases and 3 cm in those patients with tuberous sclerosis ( medians : 0.5 and 3 cm , respectively , P = .002 ) . - pubmed
In patients with tuberous sclerosis , 27 % of renal - cell neoplasms were oncocytomas , compared with 8 % in sporadic cases ( P = .15 ) . - pubmed
Also , the results suggested that betel quid chewers may harbor higher levels of infection with A. - pubmed
In conclusion , betel quid chewing was associated with a higher prevalence of bleeding on probing where higher clinical levels of disease existed , and with a likelihood of subgingival infection with A. - pubmed
A case report of acute invasive fungal rhinosinusitis in 28 year old woman with acute myeloid leukemia is described in this paper . - pubmed
METHODS : Ninety - eight patients participated in a prospective , Institutional Review Board - approved , relational database study in the Hemangioma and Vascular Birthmark Center at the Children 's Hospital of Buffalo ( Buffalo , NY ) from July 1998 to April 2000 . - pubmed
This included 68 patients with hemangiomas and 30 with vascular malformations . - pubmed
RESULTS : Fifty lesions were identified in 49 patients ( 38 portal vein and 12 hepatic vein - cava stenoses ) . - pubmed
Recurrence occurred in 9 patients : all were amenable to stenting . - pubmed
Nine patients ( 24 % ) eventually died of sepsis ( 4 ) and surgical deaths at shunt or retransplant ( 5 ) . - pubmed
All patients were diagnosed by venogram and managed by balloon dilatation alone ( n = 6 ) or stented ( n = 4 ) , with an 80 % ( 10/12 ) success , with two late recurrences amenable to repeat angioplasty or stenting . - pubmed
Patients with anterior cruciate ligament instability resulting from incomplete tears or elongation in continuity without ligament detachment historically have been treated conservatively or by graft replacement . - pubmed
Determination of serum fibrosis indexes in patients with chronic hepatitis and its significance . - pubmed
RESULTS : Among 2600 chronic hepatitis patients , every fibrotic index had a significant correlation with the inflammation grade , fibrosis staging and the degree of chronic hepatitis ( P & lt ; 0.01 ) . - pubmed
BACKGROUND : Renal transplant recipients are at increased risk of premature cardiovascular disease . - pubmed
Worth noting is the fact that it can occur in a child with height deficiency . - pubmed
A total of 189 children with bacterial complications of the acute respiratory viral infection ( ARVI)--primarily with pneumonia and bronchitis -- were dynamically examined for typical and atypical pneumotropic causative agents of the infection process ( Mycoplasma pneumoniae , Chlamydia spp . - pubmed
A high frequency rate of the associative infection involving mycoplasmas and pneumocysts was registered ( 45 - 50 % ) ; it was lower in the cases involving Chlamydias , hemophilic bacteria , pneumococcus , and cytomegalovirus -- up to 25 - 30 % . - pubmed
Pathologic study of intravascular coagulation following incompatible blood transfusion in dogs . - pubmed
METHODS : Forty 12 week - old female SD rats were randomly assigned to four groups : ( 1 ) sham operated ; ( 2 ) ovariectomized ; ( 3 ) ovariectomized and treated with estradiol ; ( 4 ) ovariectomized and received genistein , 45 mg / kg body weight per day . - pubmed
The clinical features of 15 patients with breast metastases from extramammary malignancies , excluding lymphoma , between 1982 and 2001 were retrospectively reviewed . - pubmed
Breast metastases were associated with disseminated metastatic disease in 14 of the 15 patients . - pubmed
DSM - IV mental disorders and neurological complications in children and adolescents with human immunodeficiency virus type 1 infection ( HIV-1 ) . - pubmed
METHODS : - 17 HIV - infected children presenting with psychiatric problems were included . - pubmed
We measured tissue oxygen saturation ( StO2 ) changes during a post - occlusive reactive hyperemia ( PORH ) test on lower extremities of peripheral vascular disease ( PVD ) patients and healthy controls . - pubmed
A 68 year old man presented with urethritis and a purulent discharge , carrying the tentative diagnosis of gonorrhea . - pubmed
Microbiological investigation revealed Pseudomonas aeruginosa , a relatively frequent Gram - negative bacteria in hospitals , which can cause several nosocomial diseases such as pneumonia , wound infections and urogenital infections . - pubmed
Pseudomonas aeruginosa - induced urogenital infections in ambulatory patients are extremely rare and usually not associated with a gonorrhea - like discharge . - pubmed
BACKGROUND AND AIMS : Ileal pouch - anal anastomosis ( IPAA ) improves quality of life ( QOL ) for ulcerative colitis patients who require surgery . - pubmed
METHODS We enrolled 124 patients : normal pouches ( N = 26 ) , CD of the pouch ( N = 23 ) , pouchitis ( N = 22 ) , cuffitis ( N = 21 ) , and IPS ( N = 32 ) . - pubmed
Synovial sarcoma ( SS ) is one of common malignant soft - tissue tumors and is encountered most commonly in children and young adults . - pubmed
Patients with COM stones were significantly older than patients with COD stones ( P & lt ; 0.002 ) . - pubmed
We performed 114 consecutive primary total hip arthroplasties with a cementless expansion acetabular component in 101 patients for advanced osteonecrosis of the femoral head . - pubmed
Mononuclear cell populations in the lungs of calves infected with Dictyocaulus viviparus were studied during primary infection and reinfection in order to identify cells involved in development of protective immunity to parasitic bronchitis . - pubmed
In all , 1,465 FSFTs in 8,057 trauma registry patients ( age 39 + /- 19.5 years ; Injury Severity Score [ ISS ] 23.5 + /- 14.9 ; 17.3 % mortality ) were treated initially ( & lt;24 hour ) by EF , nail , or plate in 47.0 % , 41.1 % , and 11.9 % , respectively . - pubmed
We exposed 69 wild - type and 67 mutant mice to two hyperoxic tests ( 12 - min air followed by 3 - min 100 % O2 ) 2 days after birth . - pubmed
METHODS : Teacher and parent forms of the Autism Spectrum Screening Questionnaire ( ASSQ ) were used in the " Bergen Child Study " , a total population study of 9430 children aged 7 - 9 years . - pubmed
CONCLUSION : 89SrCl2 is effective for palliation of bone pain in patients with disseminated bone metastases . - pubmed
In addition to managing pain , 89SrCl2 can improve immunity and the quality of life for most patients . - pubmed
We report 6 patients with adenolipomas of the head and neck region : 3 in the parathyroid , 2 in the thyroid , and 1 in the parotid gland . - pubmed
The patients with parathyroid adenolipomas manifested signs and symptoms of hyperparathyroidism , whereas the others complained of a mass in the neck . - pubmed
Carnitine esters prevent oxidative stress damage and energy depletion following transient forebrain ischaemia in the rat hippocampus . - pubmed
Rats in the seventh group were subjected to sham - operated ischaemia and injected with normal saline for 7 successive days . - pubmed
There were 27 patients with acute and 2 with chronic type A aortic dissection . - pubmed
One patient with acute dissection and 1 with chronic aneurysm died during the early postoperative course . - pubmed
Two patients with severe calcification of the aortic valve had strokes . - pubmed
There were no strokes in the dissection group , although there were preoperative signs of cerebral malperfusion in 4 patients . - pubmed
After a large screening on sourdough lactic acid bacteria , exopolysaccharide ( EPS)-forming strains of Weissella cibaria , Lactobacillus plantarum , and Pediococcus pentosaceus were selected . - pubmed
Compared to the sourdough started with an EPS - negative strain , the sourdough started with W. - pubmed
METHODS : Among CSS patients treated during the past 10 years at 2 French university hospitals , we have identified and described 2 cases revealed by tamponade with pericardial biopsy - proven granulomatous vasculitis . - pubmed
RESULTS : The first case report describes a 66 - year - old man who had an isolated cardiac tamponade with both inflammatory syndrome and eosinophilia . - pubmed
The second case report describes a 46 - year - old woman whose CSS presented with tamponade and associated central nervous system and myocardial involvement . - pubmed
Gefitinib in patients with progressive high - grade gliomas : a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro - Oncologia ( GICNO ) . - pubmed
To investigate the role of gefitinib in patients with high - grade gliomas ( HGGs ) , a phase II trial ( 1839IL/0116 ) was conducted in patients with disease recurrence following surgery plus radiotherapy and first - line chemotherapy . - pubmed
Adult patients with histologically confirmed recurrent HGGs following surgery , radiotherapy and first - line chemotherapy , were considered eligible . - pubmed
Patients were treated with gefitinib ( 250 mg day(-1 ) ) continuously until disease progression . - pubmed
Sixteen patients had glioblastoma , three patients had anaplastic oligodendrogliomas and nine patients had anaplastic astrocytoma . - pubmed
Gefitinib showed limited activity in patients affected by HGGs . - pubmed
Tissue from six osteoarthritic patients was obtained during revision arthroplasty . - pubmed
Since that time , there have been considerable advances in imaging techniques as well as the advent of devices to help in the management of acute stroke patients . - pubmed
Lactococcus garvieae is considered an emergent pathogen in aquaculture and it is also associated with mastitis in domestic animals as well as human endocarditis and septicaemia . - pubmed
2.4 % ) were identified which could not be recovered from rainbow trout following infection . - pubmed
During CV and VV(O ) , normal and injured mice showed regional lung collapse with increased airway pressures and poor oxygenation . - pubmed
Stroke , multiple sclerosis and Parkinson ' s disease patients also completed the Short Form 36 ( SF-36 ) Health Survey , the Multiple Sclerosis Quality of Life 54 questionnaire ( MSQoL-54 ) and the Parkinson ' s Disease Questionnaire ( PDQ-39 ) respectively . - pubmed
Stroke patients demonstrated statistically significant improvements in the Nottingham Extended Activities of Daily living Index ( mean change 3.4 , P<0.001 ) and the SF-36 mental health subsection ( mean change 7.8 , P<0.001 ) . - pubmed
Vaccinia virus ( VV ) is considered to cause lytic infection of most cells , with lysis being regarded equivalent to necrosis . - pubmed
Gentamicin increases nitric oxide production and induces hearing loss in guinea pigs . - pubmed
METHODS : A single dose of gentamicin ( 10 mg / kg body weight ) was injected intratympanally into male guinea pigs and the auditory brainstem responses were recorded before treatment and 1 , 2 , and 7 days after application . - pubmed
Comparison of magnetic resonance imaging versus Doppler echocardiography for the evaluation of left ventricular diastolic function in patients with cardiac amyloidosis . - pubmed
To assess the role of magnetic resonance imaging ( MRI ) in the assessment of diastolic function , diastolic mitral inflow parameters using MRI and transthoracic Doppler echocardiography ( echocardiography ) were compared in patients with cardiac amyloidosis . - pubmed
Thirty - eight patients ( age 60 + /- 12 years ; 32 % women ) in sinus rhythm with cardiac amyloidosis ( biopsy - proven systemic amyloidosis and positive echocardiographic and contrast - enhanced cardiac MRI findings ) were evaluated . - pubmed
In conclusion , mitral inflow peak velocities , deceleration times , and E / A ratios detected using phase - contrast MRI in patients with cardiac amyloidosis showed moderately good correlation with echocardiography and identified most patients with restrictive echocardiographic patterns . - pubmed
This demonstration of an X chromosome gene as a disease susceptibility factor in human SLE raises the possibility that the gender difference in SLE may in part be attributed to sex chromosome genes . - pubmed
METHODS : Lifetime ethanol consumption was assessed at baseline ( 1994 - 1995 ) in a prospective , population - based study in central Spain of 3285 elderly participants , 76 of whom developed incident ET by follow - up ( 1997 - 1998 ) . - pubmed
Ethanol is often used for symptomatic relief ; studies should explore whether higher consumption levels are a continued source of underlying cerebellar neurotoxicity in patients who already manifest this disease . - pubmed
Nitric oxide as a partner of reactive oxygen species participates in disease resistance to nectrotophic pathogen Botryis cinerea in Nicotiana benthamiana . - pubmed
Two subjects with adequate baseline iron stores developed erythrocytosis followed by neocytolysis . - pubmed
After giving informed consent , patients with lower - limb closed fractures rated their pain on a 10 - cm visual analog scale ( VAS ) . - pubmed
Patient evaluations of pain intensity were recorded throughout two periods : twenty - four hours pre - surgically and twenty - four hours postsurgical . - pubmed
BACKGROUND : depression has a significant prevalence in patients following a stroke . - pubmed
In phase 2 , Of the 18 patients screened , 10 patients ( 56 % ) scored 5 or above , which according to the scoring system of the PHQ-9 is indicative of depression . - pubmed
If the neurotoxicity of anaesthetics in human remains debatable , perioperative period is certainly a high - risk factor for cognitive impairment , especially in elderly population . - pubmed
Accordingly , TCF1 - deficient mice are hyperresponsive to experimental autoimmune encephalomyelitis . - pubmed
In this study , we investigated retrospectively the efficacy of rufinamide ( RUF ) in five infants with MMPEI , by examining seizure type and frequency , EEG features and antiepileptic drug use . - pubmed
The data demonstrate that two of the five patients showed good efficacy and tolerability for RUF with a & gt ; 50 % reduction in seizure frequency . - pubmed
The potential for metastasis makes recognition of CHRCC cells in cytologic preparations important for patient surveillance , management , and treatment . - pubmed
Relationship between three - year survival and functional outcome at discharge from acute - care hospitals in each subtype of first - ever ischemic stroke patients . - pubmed
BACKGROUND : We studied the relationship between survival prognosis and the functional outcome at discharge from acute - care hospitals in each subtype of ischemic stroke patients . - pubmed
METHODS : A total of 853 consecutive patients with first - ever ischemic stroke , recruited from December 1999 to November 2002 , were followed for 725.8 + - 430.0 days . - pubmed
RESULTS : The respective mortality of the groups with mRS scores of 0 - 2 , 3 , 4 , and 5 were 13.1 % , 25.0 % , 47.2 % ( p<0.05 ) , and 74.0 % ( p<0.05 ) in cardioembolic infarction ( CEI ) patients ; 11.3 % , 6.9 % , 5.6 % , and 46.7 % ( p<0.05 ) in atherothrombotic infarction ( ATI ) patients ; 8.5 % , 5.6 % , 11.1 % , and 0 % ( no patient ) in lacunar infarction ( LACI ) patients ; and 2.6 % , 3.0 % , 23.3 % ( p<0.05 ) , and 28.9 % ( p<0.05 ) in infarction of unknown cause ( IUC ) patients . - pubmed
Multi - variate analysis showed that the mRS score was a significant predictive factor for death in CEI patients , and tended to be a predictive factor for death in ATI patients , or IUC patients . - pubmed
Immunohistochemical characterization of endometriosis - associated smooth muscle cells in human peritoneal endometriotic lesions . - pubmed
METHODS : We obtained biopsies from peritoneal endometriotic lesions ( n = 60 ) and peritoneal sites distant from the endometriotic lesion ( n = 60 ) , as well as healthy peritoneum from patients without endometriosis ( control tissue , n = 10 ) . - pubmed
These controls were hysterectomy specimens from patients without endometriosis or adenomyosis . - pubmed
PURPOSE : To observe the disc - condyle relationship , joint effusion , and osseous abnormalities of the condyle before and after prosthetic rehabilitation in 8 edentulous patients with asymptomatic of bilateral temporomandibular joints ( TMJs ) . - pubmed
RESULTS : Before prosthetic rehabilitation , 10 joint disc displacements were found in 62.5 % of 16 TMJs of 8 edentulous patients , including 7 medial disc displacement , 2 lateral disc displacement and anterior disc displacement ( 6.25 % ) ; 7 TMJs had effusion 4 had condylar abnormalities . - pubmed
After prosthetic rehabilitation , 10 disc displacements were found in 16 TMJs of 8 edentulous patients , including 7 medial disc displacement , 2 lateral disc displacement , and 1 anterior disc displacement ; 7 TMJs effusion . - pubmed
CONCLUSIONS : Long - time tooth loss may lead to internal derangement of TMJ in edentulous patients . - pubmed
In short term after prosthetic rehabilitation with complete denture , there is no distinct change in disc - condylar relationship , joint effusion , and condylar abnormalities in edentulous patients . - pubmed
Because micronutrients in human diets ultimately come from plant sources , malnutrition of essential minerals is a significant public health concern . - pubmed
METHODS : : Out of consecutive 203 patients with descending thoracic aortic aneurysm , 89 ( 43.8 % ) received endovascular treatment [ mean age , 68 + - 8 years ; range , 29 - 82 ; male , 79 ( 88.7 % ) ; female , 10 ( 11.3 % ) ] without using angiography during the endovascular procedure . - pubmed
Conversion to open surgery was necessary in one patient ( 1.1 % ) because of aortic dissection . - pubmed
One patient developed paraplegia ( 1.1 % ) . - pubmed
Early endoleak was observed in eight patients ( 8.9 % ) and 4 ( 4.5 % ) required additional procedures ( proximal or distal extensions ) . - pubmed
However , NO production is reduced in CKD patients , partially due to decreased endothelial NO production . - pubmed
Potential roles for vitamins E and C in combination in modulating exhaustive swimming and high altitude - associated lung injury in rats . - pubmed
Hypoxia impedes hypertrophic chondrogenesis of human multipotent stromal cells . - pubmed
Significance of hepatic lymph node metastasis in patients with unresectable synchronous liver metastasis of colorectal cancer . - pubmed
To establish a new therapeutic strategy for initially unresectable liver metastasis of colorectal cancer , HLNs should be examined histologically in patients undergoing resection of hepatic lesions when they are rendered resectable by effective chemotherapy . - pubmed
Effects of soy on metabolic biomarkers of cardiovascular disease in elderly women with metabolic syndrome . - pubmed
Participants were 75 women , ages 60 - 70 years , who were diagnosed with MetS. - pubmed
Gender - dependence of bone structure and properties in adult osteogenesis imperfecta murine model . - pubmed
Though the oim mouse model has been the most widely studied of the OI models , it has only recently been suggested to exhibit gender - dependent differences in bone mineralization . - pubmed
This study provides evidence of the importance of gender in the evaluation and interpretation of potential therapeutic strategies when using mouse models of OI . - pubmed
Immunophenotypic characterization and quantification of neoplastic bone marrow plasma cells by multiparametric flow cytometry and its clinical significance in Korean myeloma patients . - pubmed
We analyzed the MFC data of the bone marrow aspirates of 76 patients with PCM and 33 patients with reactive plasmacytosis . - pubmed
The plasma cells of patients with reactive plasmacytosis demonstrated normal immunophenotypic patterns . - pubmed
PURPOSE OF REVIEW : To provide an overview on the available clinical and pathological factors in high - risk nonmuscle invasive bladder cancer ( NMIBC ) patients that help to approximate the risk of progression to muscle invasion and identify ' the ' patients requiring timely cystectomy . - pubmed
RECENT FINDINGS : Carcinoma in situ within the prostatic urethra of NMIBC patients impacts on patient 's outcome . - pubmed
Recent findings from patients undergoing radical cystectomy including super - extended lymphadenectomy for clinically NMIBC confirm the substantial rate ( 25 % ) of tumor understaging . - pubmed
The fact that almost 10 % were found to harbor lymph node metastases underlines the necessity to perform a meticulous lymphadenectomy in NMIBC patients undergoing radical cystectomy . - pubmed
Nevertheless , tumor understaging remains an issue of concern and warrants the value of a second transurethral resection in high - risk NMIBC patients . - pubmed
There is a persisting lack of rigid therapeutic recommendations in patients with high - risk NMIBC . - pubmed
However , irrespective of initial treatment strategy , there is a subgroup of high - risk NMIBC patients with progressive disease , leading almost inevitably to death . - pubmed
Role of RNA structure motifs in IRES - dependent translation initiation of the coxsackievirus B3 : new insights for developing live - attenuated strains for vaccines and gene therapy . - pubmed
Translation initiation of the coxsackievirus B3 ( CVB3 ) , a causative agent of viral myocarditis , has been shown to be mediated by a highly ordered structure of the 5 ' untranslated region ( 5'UTR ) , which harbors an IRES . - pubmed
Since translation initiation is the first intracellular step during the CVB3 infection cycle , the IRES region provides an ideal target for antiviral therapies . - pubmed
Phytochemical screening and cytotoxicity studies of Chrysophyllum pruniforme Pierre ex Engl . - pubmed
Legumes and whole grains can modulate risk markers associated with cardiometabolic diseases , but their possible additive / synergistic actions are unknown . - pubmed
DESIGN AND METHODS : Sixteen subjects with traumatic brain injury ( five males and 11 females ; aged 22 - 34 years ) participated in the experiment . - pubmed
This sensor can potentially be used clinically as a subcutaneously implanted continuous monitoring device in diabetic patients . - pubmed
In vitro quantitative analysis , using strains isolated from wounds , showed that NxtSc inhibited biofilm development by Staphylococcus aureus , Staphylococcus epidermidis , Pseudomonas aeruginosa , Acinetobacter baumannii , and Klebsiella pneumoniae by inhibiting bacterial growth . - pubmed
Markers of endothelial cell dysfunction are increased in human omental adipose tissue from women with pre - existing maternal obesity and gestational diabetes . - pubmed
OBJECTIVE : To determine the effect of maternal obesity and gestational diabetes mellitus ( GDM ) on the expression and release of genes involved in endothelial cell dysfunction in human placenta and omental adipose tissue . - pubmed
MATERIALS / METHODS : Human placenta and omental adipose tissue were obtained from non - obese and obese normal glucose tolerant ( NGT ) women and women with GDM at the time of Caesarean section . - pubmed
Alveolar macrophages are considered the first cells infected by Mtb during respiratory infection . - pubmed
The definition of the cellular and molecular mechanisms involved in the immune response to Mtb can be helpful in developing new preventive strategies to avoid infection relapse , particularly in patients treated with biological agents . - pubmed
METHODS : We treated 10 eyes of nine patients with PED ( Stevens - Johnson syndrome : three eyes ; thermal / chemical injury : five eyes ; ocular cicatricial pemphigoid : two eyes ) with COMET at Kyoto Prefectural University of Medicine , Kyoto , Japan from 2002 to 2008 . - pubmed
CONCLUSION : COMET enabled complete epithelialization of PED and stabilization of the ocular surface in patients with severe ocular surface disease , thus preventing end - stage cicatrization and vision loss at a later stage . - pubmed
CONCLUSIONS : PMRT is indicated in patients who are deemed to have a high risk of loco - regional recurrence . - pubmed
Resting - state studies conducted with stroke patients are scarce . - pubmed
Eleven patients ( eight male and three female ; age range : 48 - 72 ) with right cortical and subcortical ischemic infarctions and 17 controls ( eleven males and six females ; age range : 57 - 69 ) were assessed by neurological and neuropsychological examinations and scanned with resting - state functional magnetic ressonance imaging . - pubmed
METHODS : Eighty - four patients with bipolar disorder were evaluated . - pubmed
Both entities normally occur without adequate trauma and predominantly in elderly patients . - pubmed
Herbal medicines and food supplements containing PAs are also recognized as a significant cause of human poisoning and it is desirable that such medications are identified and subjected to strict regulation . - pubmed
Arnebin-1 , a naphthoquinone derivative , plays a crucial role in the wound healing properties of Zicao ( a traditional wound healing herbal medicine ) . - pubmed
Therefore , the findings of the present study indicate that arnebin-1 promotes the wound healing process in diabetic rats by eliciting a pro - angiogenic response . - pubmed
CHARACTERISTICS AND OUTCOMES OF PATIENTS WITH CHRONIC MYELOGENOUS LEUKEMIA IN BLAST CRISIS . - pubmed
METHODS : Clinical records of 20 patients with CML who transformed to BC in two years between January 2012 and December 2013 were reviewed . - pubmed
RESULTS : Out of total 240 patients , 20 ( 8.3 % ) transformed to blast crisis ; among them 75 % were males and 25 % females . - pubmed
Eight patients ( 40 % ) were transformed to acute myeloid leukaemia ( AML ) and 12 ( 60 % ) had acute lymphoblastic leukaemia ( ALL ) . - pubmed
These patients were treated with standard AML / ALL type induction chemotherapy except one who died early . - pubmed
Influence of Toxoplasma gondii Infection on Male Fertility : A Pilot Study on Immunocompetent Human Volunteers . - pubmed
BACKGROUND : This study was conducted to investigate the influence of Toxoplasma gondii infection on spermatic and hormonal parameters in a pilot sample of immunocompetent human male subjects . - pubmed
Here we identify cell types positive for rubella virus ( RV ) in CRS infants . - pubmed
Participants were 11 clinically diagnosed PD patients and 10 age and gender matched healthy controls ( HCs ) . - pubmed
METHODS : Pigs with ischemic BBS were endoscopically treated either with BDBS or CSEMS . - pubmed
Samples were harvested from pigs with intact BD ( n = 5 ) , untreated BBS ( n = 5 ) , and after six months of therapy with BDBS ( n = 4 ) or CSEMS ( n = 5 ) with subsequent histologic analysis . - pubmed
Alteration of Human Papillomavirus Type 16 Genetic and Epigenetic Profiles in Cervical Cancer Patients Is Indicative of Poor Disease Prognosis : A Cohort Analysis . - pubmed
OBJECTIVE : Aim of this study was to assess the changes in genetic and epigenetic profiles of human papillomavirus type 16 ( HPV16 ) , if any , in primary cervical cancer ( CaCx ) and corresponding plasma before and after therapy for possible prognostic evaluation . - pubmed
RESULTS : Presence of HPV16 in the patients ' plasma before / after therapy was significantly ( P = 0.03 ) associated with higher viral load in the primary tumor site . - pubmed
Whereas in the posttherapy swabs , integrated ( 22 of 29 ) or mixed ( 7 of 29 ) form of HPV16 prevailed with hypomethylation of the enhancer ( 6 of 29 , Z = 2.0 , P & lt ; 0.05 ) and late promoter ( 18 of 29 , Z = 4.4 , P & lt ; 0.01 ) compared with the corresponding primary tumors . - pubmed
The patients having high HPV16 copy number in pretherapy and posttherapy cervical lesions and hypomethylation of early promoter / late promoter in the corresponding plasma showed increased disease recurrence with distant metastases . - pubmed
CONCLUSIONS : The genetic - epigenetic profile of HPV16 in pretherapy / posttherapy CaCx samples showed significant association with disease prognosis . - pubmed
Among patients with grade 0 adhesions , 34 ( 13.7 % ) had no striae , while 79 ( 31.9 % ) had mild - to - severe striae ( p & lt ; 0.001 ; sensitivity 55 % ; specificity 67 % ; positive predictive value 69 % ; negative predictive value 52 % ) . - pubmed
Among women with grade 1 - 2 adhesions , 48 ( 19.4 % ) had no striae , while 58 ( 23.4 % ) had mild - to - severe striae . - pubmed
We propose the following practical considerations to preserve RKF , especially in newly transitioned ( incident ) hemodialysis patients : ( 1 ) periodic monitoring of RKF in hemodialysis patients through urine volume and including residual urea clearance with dialysis adequacy and outcome markers such as anemia , fluid gains , minerals and electrolytes , nutritional , status and quality of life ; ( 2 ) avoidance of nephrotoxic agents such as radiocontrast dye , nonsteroidal anti - inflammatory drugs , and aminoglycosides ; ( 3 ) more rigorous hypertension control and minimizing intradialytic hypotensive episodes ; ( 4 ) individualizing the initial dialysis prescription with consideration of an incremental / infrequent approach to hemodialysis initiation ( e.g. - pubmed
The patients were separated into two groups as histologically observed prostatitis ( Group A ) and no prostatitis ( Group B ) according to the biopsy outcomes . - pubmed
Mean international prostate symptom score in patients with prostatitis was numerically but not significantly higher than that in those without prostatitis ( t=0.794 , P=0.066 ) . - pubmed
Histological prostatitis notably affected sexual function of patients and may serve as a major risk factor for sexual dysfunction while having little effect on lower urinary tract symptoms . - pubmed
We attempt to dissect the pathology of non - small cell lung cancer ( NSCLC ) patients at different stages and discover the novel candidate genes . - pubmed
Impact of groin flap ischemia - reperfusion on red blood cell micro - rheological parameters in a follow - up study on rats . - pubmed
Patients were retrospectively classified into two groups based on whether they developed severe sepsis or septic shock during the postoperative period . - pubmed
BACKGROUND : Posaconazole is approved for invasive fungal infection prophylaxis in patients with hematologic malignancies . - pubmed
OBJECTIVES : We sought to determine if a switch to posaconazole tablets improved steady - state drug level attainment for invasive fungal infection prophylaxis in patients with acute myeloid leukemia . - pubmed
METHODS : All adult inpatients with acute myeloid leukemia undergoing chemotherapy , who received posaconazole for invasive fungal infection prophylaxis between 2012 and 2015 , were included . - pubmed
Secondary outcomes included proportion of patients with first posaconazole level greater than 1000 ng / mL , invasive fungal infection within 100 days , and adverse drug events . - pubmed
Scaffold - supported Transplantation of Islets in the Epididymal Fat Pad of Diabetic Mice . - pubmed
Here , we report a robust protocol for the transplantation of islets at the extrahepatic transplantation site - the epididymal fat pad ( EFP)-in a diabetic mouse model . - pubmed
We present the first direct evidence that B19V infection of erythroid progenitor cells disrupts the human genome and facilitates viral DNA integration . - pubmed
OBJECTIVE : To evaluate the role of quantitative digital subtraction angiography ( Q - DSA ) with parametric color coding ( PCC ) in assessing patients with type B chronic thoracic aortic dissection ( TBCAD ) during thoracic endovascular aortic repair ( TEVAR ) procedures . - pubmed
CONCLUSIONS : Our results indicate that Q - DSA could be useful in the intraprocedural evaluation of patients with aortic dissection during TEVAR procedures without additional x - ray costs and contrast exposure . - pubmed
Laboratory impacts were performed at 12 locations distributed over the helmet and the resulting head kinematics were simulated in two finite element models of the brain : the Simulated Injury Monitor and the Global Human Body Model Consortium brain model . - pubmed
Methods : Sixty - four male nude mice bearing tumor xenografts were randomly divided into four groups . - pubmed
Cell culture was performed using the human gastric adenocarcinoma cell line SGC-7901 . - pubmed
Mice with tumor xenografts were treated with propranolol , isoproterenol , and radiation . - pubmed
Results : The growth in the volume and weight of the tumor was lower in mouse models treated with propranolol and radiation therapy compared to the other groups . - pubmed
The percentage of circulating Th17 and Th22 cells was significantly increased in CC patients compared to that in healthy controls ( HCs ) . - pubmed
The patient was diagnosed with small bowel obstruction and taken for exploratory laparotomy . - pubmed
In addition to 10 control patients with no ED or chronic HCV ( Group D ) . - pubmed
There were significant differences in Hcy between patients with Child B and Child C. A strong association between severity of ED and chronic HCV was demonstrated . - pubmed
Indocyanine green fluorescence - imaging ( ICG - FI ) has emerged as a potential tool for increasing the accuracy of staging of patients with primary colorectal cancer ( CRC ) through the detection of sentinel lymph nodes ( SLNs ) . - pubmed
ICG - FI is a promising technique for the detection of SLNs in the setting of CRC but more work needs to be done to clearly define protocols and indications for its use and to test its efficacy in larger patient populations . - pubmed
HHH is the rarest of the urea cycle disorders , reported in fewer than 100 patients . - pubmed
To model chronic migraine C57BL/6J mice received chronic intermittent treatment with the known human migraine trigger , nitroglycerin . - pubmed
For MOH and OIH , mice were chronically treated with sumatriptan or morphine , respectively . - pubmed
In addition , we showed that MNCaposec accelerated wound closure in a diabetic mouse model . - pubmed
Effect of laminar air flow and building construction on aspergillosis in acute leukemia patients : a retrospective cohort study . - pubmed
BACKGROUND : The preventive effect of laminar air flow ( LAF ) on aspergillosis has been observed in patients with hematological malignancies . - pubmed
METHODS : To assess the preventive effect of long - term LAF use on aspergillosis in its long - term use , we retrospectively analyzed 124 acute leukemia patients at our hospital between January 2005 and March 2016 . - pubmed
RESULTS : Fourteen patients were diagnosed with possible , probable , or definite aspergillosis . - pubmed
INTRODUCTION : In patients with liver lesions with ductal extension , the corresponding Glissonean pedicle should be divided at its origin to achieve a negative ductal margin ; however , during laparoscopic hepatectomy , it is difficult to precisely transect the liver and divide the Glissonean pedicle as planned . - pubmed
Typical enteropathogenic Escherichia coli ( typical EPEC ) and Cryptosporidium were the two pathogens associated to an increased risk of death in the univariate analysis with ( HR = 4.16 , p = 0.0461 ) and ( H = 2.84 , p = 0.0001 ) respectively . - pubmed
When restricting the analysis to those with available HIV results ( n = 191 , 22 % of the total study sample ) , HIV was shown to be a significant risk factor for death ( HR = 5.05 , p = 0.0009 ) . - pubmed
Verbal autopsies were conducted in 100 % of study deaths , and highlighted diarrhea as the main underlying cause of death 39 % , ( 27/69 ) ; followed by HIV / AIDS related deaths 29.0 % ( 20/69 ) and sepsis 11.6 % ( 8/69 ) . - pubmed
RESULTS : Two of 44 ( 5 % ) patients had bone marrow involvement . - pubmed
These two patients had no relapse during follow - up , either cutaneous or extra - cutaneous . - pubmed
Animal model of arthritis and myositis induced by the Mayaro virus . - pubmed
BACKGROUND : The Mayaro virus ( MAYV ) is an endemic arbovirus in South American countries , where it is responsible for sporadic outbreaks of Mayaro fever . - pubmed
For pain analysis , the animals were submitted to the von Frey test and titre in different organs was evaluated throughout the study to obtain viral kinetics . - pubmed
Airway clearance techniques for patients with acute exacerbations of chronic obstructive pulmonary disease : Physical therapy practice in Sweden . - pubmed
Efficacy and safety results from a phase 1b/2 , multicenter , open - label study of oprozomib and dexamethasone in patients with relapsed and/or refractory multiple myeloma . - pubmed
Our phase 1b/2 study examined the safety and efficacy of oprozomib with dexamethasone in patients with relapsed and refractory MM . - pubmed
Influence of shortened recovery between resistance exercise sessions on muscle - hypertrophic effect in rat skeletal muscle . - pubmed
To elucidate the effect of recovery period on hypertrophy , in the present study , we investigated changes in protein degradation systems and hypertrophic responses in rat skeletal muscle to resistance training with variable recovery periods . - pubmed
Prophylactic simvastatin treatment modulates the immune response and increases survival of mice following induction of lethal sepsis . - pubmed
Development of antifungal agents with novel mechanism and low toxicity are essential due to the prevalence of the infectious diseases caused by Candida albicans . - pubmed
BACKGROUND : Pazopanib can induce liver toxicity in patients with metastatic renal cell carcinoma ( mRCC ) . - pubmed
RESULTS : Of 261 patients , 34 ( 13 % ) had developed liver toxicity after a median of 29 days ( range , 5 - 155 days ) . - pubmed
Degenerative cervical myelopathy ( DCM ) is the leading cause of spinal cord dysfunction in adults worldwide . - pubmed
OBJECTIVES : To compare the prognostic role of FVC and SVC at diagnosis in amyotrophic lateral sclerosis ( ALS ) patients . - pubmed
METHODS : We included all patients from the Piemonte and Valle D'Aosta ALS register ( PARALS ) who had been diagnosed with ALS between 1995 and 2015 and underwent spirometry at diagnosis . - pubmed
RESULTS : A total of 795 ALS patients underwent spirometry at diagnosis during the study period . - pubmed
A 54 - year - old Japanese woman presented with acute severe neck pain . - pubmed
The patient was diagnosed with acute calcific retropharyngeal tendinitis and treated with a soft collar and non - steroidal anti - inflammatory drugs . - pubmed
BACKGROUND : Front - loaded diazepam is used to rapidly control agitation in patients with severe alcohol withdrawal syndrome ( AWS ) . - pubmed
Patients who received front - loaded lorazepam had an increased incidence of ICU - delirium ( positive for the Confusion Assessment Method in the ICU : 75 % with lorazepam vs. 52.6 % with diazepam , p = 0.009 ) and a higher risk of over - sedation , but this did not reach statistical significance ( Richmond Agitation - Sedation Scale score < -1 : 32.1 % with lorazepam vs. 18.2 % with diazepam , p = 0.063 ) . - pubmed
The aim of this work was to investigate on the animal model of metabolic syndrome , i.e. - pubmed
Administration of venlafaxine caused the decrease of heart weight / body weight index in rats fed with HFFD compared to the untreated group fed with HFFD for 8 weeks . - pubmed
BACKGROUND : Coronavirus disease 2019 ( Covid-19 ) occurs after exposure to severe acute respiratory syndrome coronavirus 2 ( SARS - CoV-2 ) . - pubmed
Whether hydroxychloroquine can prevent symptomatic infection after SARS - CoV-2 exposure is unknown . - pubmed
This is the first demonstration of a microRNA OE mouse model that has ectodermal organ defects . - pubmed
Patients were classified according to HRCT findings into five groups : usual interstitial pneumonia ( UIP ) , non - specific interstitial pneumonia ( NSIP ) , desquamative interstitial pneumonia ( DIP ) , combined pulmonary fibrosis and emphysema ( CPFE ) , and non - specific - ILD . - pubmed
Neoadjuvant Biologic Therapy in the Surgical Management of Patients with Hidradenitis Suppurativa : A Cohort Study . - pubmed
For rabbits , boosts should be spaced every 6 wk , and serum samples of 20 - 40 mL should be collected ~10 - 12 d after each boost ; typically , a single sample bleed from a rabbit will yield 25 mL of serum . - pubmed
Anti - rheumatoid arthritis effects of iridoid glucosides from Lamiophlomis rotata ( Benth . ) - pubmed
In a 4 - week intervention trial , overweight subjects were randomized to consume either arabinoxylan - oligosaccharides ( AXOS ) ( 10.4 g / d ) from wheat bran or polyunsaturated fatty acids ( PUFA ) ( 3.6 g / d ) . - pubmed
Refractory disease is a major challenge in treating patients with acute myeloid leukemia ( AML ) . - pubmed
Influenza in China in 1977 : recurrence of influenzavirus A subtype H1N1 . - pubmed
The influenza epidemic caused by the H1N1 virus was characterized by slow spread , unevenness of attack rates , and the occurrence of many mild cases and inapparent infections . - pubmed
[ Therapeutic and protective regimen for children with chronic pneumonia ] . - pubmed
The successful surgical removal of a feminizing adrenal tumour in a postmenopausal woman is described . - pubmed
Recurrent ventricular tachyarrhythmias required multiple resuscitative efforts with electrical countershock in a 45 - year - old woman with previously undiagnosed asymptomatic congenital prolongation of the Q - T interval . - pubmed
The results of brain scanning in 64 patients with histologically proven meningiomas are presented , and the accuracy of this diagnostic method is assessed . - pubmed
Primitive neuroectodermal tumor ( neuroblastoma ) arising in sciatic nerve of a child . - pubmed
A well - documented case of a primitive neuroectodermal tumor ( neuroblastoma ) arising in the sciatic nerve of a 6 - year old boy is presented . - pubmed
After radical surgical excision of the tumor , followed by chemotherapy , the child remained clinically free of disease for 20 months . - pubmed
The incidence and type of x - ray semeiotics of the skull involvement were studied in 703 patients with endocrine diseases ( 26 with acromegaly , 36 with hypercorticism , 104 with thyrotoxicosis , 23 with hypothyrosis , 98 with primary hyperparathyrosis , 302 with diabetes mellitus , 114 with hypogonadism ) . - pubmed
However , a strain of V. - pubmed
In the present study , only mobile , relatively healthy , adequately nourished outpatients with probable AD were selected . - pubmed
In comparison to age - matched controls or demented subjects with even mild indications of vascular contributions , the AD subjects were characterized by lower serum PO4 and , to a lesser degree , lower serum Ca as well as a higher chloride / PO4 ratio . - pubmed
from the control group mean ) identified 74 % of all AD subjects and 100 % of early onset AD subjects , in comparison to only 46 % of mixed / vascular dementia subjects and 31 % of normal age - matched controls . - pubmed
Adherence of Candida albicans to tissues from mice with genetic immunodeficiencies . - pubmed
In general , immunodeficiencies significantly decreased binding of C. - pubmed
Underutilization of thrombolytic therapy in eligible women with acute myocardial infarction . - pubmed
Twenty - three lines of chickens , obtained from grandparent stocks of 4 Australian breeding companies , were analysed to determine the incidence of early embryonic mortality attributable to chromosome abnormalities . - pubmed
The lines included 10 layer strains , consisting of 6 White Leghorn , 2 New Hampshire and 2 Australorp lines , and 13 broiler lines . - pubmed
Bypass to the pedal arteries was performed with use of the operating microscope and standard microsurgical technique in 37 patients with severe , chronic ischemia of a lower extremity . - pubmed
Twenty - one patients ( 57 % ) had three or more cardiovascular risk factors , and 22 ( 59 % ) had diabetes . - pubmed
No early deaths occurred , and only one patient had a perioperative myocardial infarction . - pubmed
Of the 34 patients who were alive at the time of this report , 27 ( 79 % ) had a functional foot that allowed ambulation , had no rest pain , and had no substantial loss of tissue . - pubmed
Pedal bypass should be considered for critical , chronic ischemia , even if the patient has an increased surgical risk and advanced distal atherosclerotic disease . - pubmed
[ The late results of the combined treatment of kidney cancer patients ] . - pubmed
Randomized study with inclusion of certain types of immunotherapy in the schedule of complex treatment was conducted in 89 patients with kidney carcinoma after the operation . - pubmed
In 63 patients the tumor was in stage T3N0M0 . - pubmed
Multiple metastases occurred in 26 patients . - pubmed
Measures for increasing the activity of the immune and macrophagal systems should be included in the schedule of complex treatment for patients with carcinoma of the kidney . - pubmed
To evaluate premarital human immunodeficiency virus ( HIV ) screening as an approach to AIDS prevention in the United States , we determined the HIV antibody seroprevalence in marriage license applicants in eight areas by blinded testing of blood specimens routinely collected for syphilis serology . - pubmed
An 8 - year - old boy , presenting with signs of chronic meningitis , and involvement of cranial nerves , was found to have neurobrucellosis . - pubmed
The development of angiotensin - converting enzyme ( ACE ) inhibitors has been important in furthering our understanding of the pathophysiology of congestive heart failure and improving the care of these patients . - pubmed
ACE inhibitors have been shown to improve the longevity and quality of life of patients with congestive heart failure . - pubmed
, 216 Haemophilus parainfluenzae and 28 Haemophilus influenzae strains being isolated . - pubmed
Female ( NZBxNZW)F1 mice were fed for one month with a diet in which the sources of fat were either melted beef tallow or fish oil , the latter regimen being associated with a marked decrease in the expression of auto - immune disease in these animals . - pubmed
To test whether or not this beneficial effect was associated with an increased risk of infection , animals fed each of these diets were challenged intraperitoneally with graded doses of four different classes of microorganisms : a gram positive bacillus that is an intracellular parasite ( Listeria monocytogenes ) , an exotoxin - producing gram negative bacillus ( Pseudomonas aeruginosa ) , a yeast ( Candida albicans ) , and a herpes group virus ( murine cytomegalovirus ) . - pubmed
We conclude that the beneficial anti - inflammatory effects of fish oil diets in these mice are not associated with an increased risk of infection with a variety of microbial agents . - pubmed
[ Acute diseases of the gallbladder and pancreas in patients with severe trauma and shock ( characteristics of the diagnosis and treatment ) ] . - pubmed
Under study were 56 observations of posttraumatic cholecystitis and pancreatitis in patients with polytrauma without a direct injury of the gallbladder and pancreas . - pubmed
Apomorphine - induced rotation was significantly suppressed in 11 out of 26 rats from two through ten weeks after the implantation . - pubmed
Two groups of rats were treated for epididymitis in an experimental study . - pubmed
The developing infection of E. - pubmed
A subgroup of seven resection patients without fat and bile acid malabsorption served as controls . - pubmed
Of the resection patients , eight had a pure bile acid malabsorption and 15 a combination of fat , bile acid , and modest cholesterol malabsorption . - pubmed
The concentrations of the precursor sterols were similarly increased in the subjects with bile acid and cholesterol malabsorption , the two lathosterols showing the highest correlations with the overall cholesterol synthesis ( r = 0.820 - 0.941 ) . - pubmed
In the subjects with jejunoileal bypass cholesterol malabsorption effectively regulated cholesterol synthesis and the precursor levels . - pubmed
Metronidazole significantly improved the results in the anaemic cases , but had no effect on the non - anaemic patients . - pubmed
It is concluded that anaemia has a prognostic value , and anaemic patients may represent a particular group for which hypoxic cell sensitizers can be expected to improve the effect of radiotherapy . - pubmed
Necropsy findings in a child with FG syndrome . - pubmed
We conducted a prospective investigation of the effect of coffee consumption on coronary heart disease in 1130 male medical students who were followed for 19 to 35 years . - pubmed
Coronary " calcific " embolisation must be considered in the differential diagnosis of symptoms of ischemic heart disease in patients suffering from valvular heart lesions . - pubmed
In twenty - four patients with intolerance to cold after partial or complete finger amputations , lower skin temperature together with cold and vibration allodynia ( allodynia = pain due to a non - noxious stimulus to neural skin ) were found in the cold intolerant area compared with the corresponding area in the uninjured hand . - pubmed
The patients had several features in common with reflex sympathetic dystrophies , and we suggest that neurogenic rather than vascular disturbances are mainly involved in the post - traumatic cold intolerance syndrome . - pubmed
Slices of human prostatic adenocarcinoma obtained by transurethral resection were maintained in organ culture for 4 days . - pubmed
Inhibition by H-1 virus of the incidence of tumors produced by adenovirus 12 in hamsters . - pubmed
Multiple infections among newborns resulting from colonization with Staphylococcus aureus 502A. - pubmed
They inhibited the hypotensive effect of SP in the anesthetised rats , the vasodilator effect in the rabbit perfused heart and the relaxation induced by SP in dog carotid arteries contracted with noradrenaline . - pubmed
Proximal renal tubular function was studied in 11 patients with severe burn injury . - pubmed
Twenty - four - hour urine glucose excretion exceeded 1 g in five patients , aminoaciduria was noted in eight , and proteinuria , predominantly globulinuria , was present consistently . - pubmed
Metabolic acidosis was seen in one patient , and transient hypokalemia occurred in two . - pubmed
Abnormalities of proximal tubular function were more marked in the five patients with the greatest extent of third - degree burns who died . - pubmed
In all 3 cases when captopril ( 0.3 mg / Kg ) was administered intravenously to donor dogs , the blood pressure decreased and a slight tachycardia usually appeared . - pubmed
The Alaska salmon industry conducted 9 recalls of 7 3/4 - oz cans of salmon in 1982 after a 7 3/4 - oz can of Alaskan salmon was implicated in illness and one death in Belgium from Clostridium botulinum type E toxin . - pubmed
Collagens extracted from bones , cartilage , dermis , and dura mater of an infant with type II ( lethal perinatal ) osteogenesis imperfecta were evaluated with respect to chain composition and chemical characteristics of their constituent chains . - pubmed
One - year survival is infrequent in patients with metastatic cancer to the liver . - pubmed
The subset of patients ( 16 ) with colorectal adenocarcinoma had a 7 - year survival rate of 29 % after hepatic resection . - pubmed
We conclude that hepatic resection for isolated hepatic metastases can be performed with acceptable morbidity , low mortality , and prolongation of patient survival . - pubmed
Using the incomplete cerebral hemisphere infarction in dogs , we have been able to produce brain swelling in all animals after six hours of vascular occlusion followed by recirculation of blood . - pubmed
Noteworthy is the fact that among these experimental groups , there were animals in which brain swelling was severe , yet extravasation of Evans blue was slight and , contrarily , animals in which brain swelling was slight but extravasation severe . - pubmed
To gain insight into the operative mechanism of RA and to study the agreement between the two quantitative angiographic methods in measuring the minimal luminal cross - sectional area , the edge detection and videodensitometry techniques were applied to coronary angiograms of 21 lesions in 19 patients with symptoms who underwent successful RA and balloon angioplasty ( BA ) . - pubmed
Acute myelopathy in children . - pubmed
Because of the high risk of adenocarcinoma in Barret ' s esophagus , endoscopic surveillance of all patients with acceptable surgical risk is recommended . - pubmed
The remote phylogenetic relationship between the two bird parasites , Plasmodium gallinaceum and Plasmodium lophurae , and any of the human parasites provides no support for the hypothesis that infection by Plasmodium falciparum is a recent acquisition of humans , possibly coincident with the onset of agriculture . - pubmed
Between 1980 and 1990 we treated 12 patients ( median age 43 years , range 16 - 62 ) with collecting duct carcinoma of the kidney . - pubmed
They induce hepatocellular carcinoma in rats and birds , and are suspected of being carcinogenic to humans . - pubmed
To better understand the genotoxic effects of PCBs , we used 32P - postlabelling to investigate DNA adduct formation , after exposure to PCBs ( Aroclor 1254 and 3,3 ' , 4,4 '- tetrachlorobiphenyl ) , in primary cultures of fetal hepatocytes from two animal species and in a human cell line ( Hep G2 ) . - pubmed
Remodeling rather than neointimal formation explains luminal narrowing after deep vessel wall injury : insights from a porcine coronary ( re ) stenosis model . - pubmed
BACKGROUND : Oversized balloon dilatation of normal porcine coronary arteries usually heals without stenosis formation . - pubmed
In 9 pigs ( group 2 ) examined postmortem 3 weeks after dilatation , histology revealed that the injury was deep ( out to adventitia ) in all arteries and completely circumferential ( 360 degrees ) in all but two arteries . - pubmed
METHODS : PC-3 human prostate carcinoma cells were exposed to 50 - 200 nM jasplakinolide ( Jas ) or cytochalasin E ( CyE ) in cytotoxicity experiments . - pubmed
Effective treatment of the multiply injured trauma patient . - pubmed
We describe a newborn girl who had been exposed to idarubicin and cytosine - arabinoside during the second and third trimesters of pregnancy due to treatment of newly diagnosed acute myeloid leukemia in the mother . - pubmed
The child had no structural congenital abnormalities . - pubmed
However , 2 of the 6 patients whose ALs continued experienced a pneumothorax . - pubmed
After - the - fact strategies Mexican Americans use to prevent HIV and STDs . - pubmed
Their preventive practices for both HIV and STDs centered around a " gonorrhea model " of prevention and casual transmission . - pubmed
METHODS : Inflamed sigmoid colon epithelium from UC patients was studied by alternating current impedance analysis to determine the pure epithelial resistance as a measure of intestinal barrier function . - pubmed
Photodynamic therapy in women with cervical intraepithelial neoplasia using topically applied 5 - aminolevulinic acid . - pubmed
We performed a study of topically applied 5 - aminolevulinic acid ( 5 - ALA ) in the photodynamic treatment of women with high - grade cervical intraepithelial neoplasia ( CIN ) using fixed 5 - ALA doses and application protocols derived from previous in vitro and in vivo results . - pubmed
Ten treatment cycles of PDT using 5 - ALA were performed in 7 patients with high - grade CIN . - pubmed
Local toxicity was minor as several patients reported burning sensations and vaginal discharge , but no necrosis , sloughing or scarring occurred . - pubmed
RESULTS : Mice sensitized and challenged with pollen developed clinical signs consistent with human allergic conjunctivitis . - pubmed
All the human strains were gentamicin sensitive , while streptomicin and cloxacillin were resistant . - pubmed
Erythromycin had a high activity ( 83.3 % ) on human strains and only 59.6 % activity on animal strains . - pubmed
In an in vivo study , employing nitrosomethylurea - induced mammary tumours in intact rats , 2 - MeOE1 ( 20mg / kg / d , p.o . - pubmed
MATERIAL AND METHODS : An open cross - over randomised trial enrolled 29 anginal patients . - pubmed
10 patients retained signs of myocardial ischemia at BE though they were treated with specially selected antianginal drugs . - pubmed
Continuous lamivudine treatment in an OLT patient despite the appearance of HBV resistant strain : longitudinal analysis . - pubmed
Primary locally infiltrative gastrointestinal aspergilloma in a non - neutropaenic child . - pubmed
The patient finally died due to sepsis and gastrointestinal bleeding . - pubmed
In stroke patients , brain SPECT images with Tc-99 m HMPAO can predict fatal cerebral hemorrhage caused by anti - thrombic therapy by showing the decrease in count ratio ( count ratio of infarcted to contralateral area of & lt ; 0.34 ) in the acute phase and identifying disruption of the blood brain barrier by showing hyperfixation in the subacute phase . - pubmed
Model systems : modeling human staphylococcal arthritis and sepsis in the mouse . - pubmed
Murine models of Staphylocococus aureus - mediated arthritis and sepsis exist and are being used to gain a better understanding of the host - bacterium relationship as well to develop better methods of prevention and treatment . - pubmed
BACKGROUND : Nowadays a number of diverse biochemical markers have been identified in patients with heart failure ( HF ) that could indicate the severity of the patients ' illness . - pubmed
PATIENTS AND METHOD : We studied 114 patients admitted consecutively for symptomatic HF for all causes ( age : 66 years , male : 60 % ) . - pubmed
One of the C - peptides , T-20 , which is in the phase III clinical trials , has potent in vivo activity against HIV infection and is expected to become the first peptide HIV fusion inhibitory drug in the near future . - pubmed
The aim of the present study was to evaluate both clinical features and treatment in a subgroup of patients with ruptured liver tumours . - pubmed
From 1995 to 2000 , 20 patients were referred to our centre for spontaneous rupture of a liver tumour associated with haemoperitoneum . - pubmed
Hepatocellular carcinoma ( HCC ) was present in 13 patients ( 11 men and 2 women ) aged from 48 to 72 years ( mean 62 ) and adenoma in 7 women aged from 23 to 52 years ( mean 35 ) . - pubmed
In patients with HCC , severe liver insufficiency ( Child - Pugh C ) was present in 5 cases including the 3 shocked patients . - pubmed
In hospital , mortality was observed in 3 ( 23 % ) patients , all of them had severe liver insufficiency . - pubmed
In patients with adenoma , shock at admission was observed in only 1 patient under anticoagulation treatment . - pubmed
A decrease of the tumour size was observed in patients who underwent delayed resection resulting in a lower rate of peri - operative transfusion . - pubmed
In conclusion , this study confirms that the majority of patients with ruptured liver tumours had no evidence of haemodynamic instability and therefore should be initially managed conservatively . - pubmed
In patients with single ruptured HCC associated with good liver function , long - term survival can be observed after liver resection . - pubmed
Delayed resection facilitated the operative procedure in patients with ruptured adenoma . - pubmed
The incidence of mandibular ORN in head and neck cancer patients managed with radical or postoperative irradiation , has varied widely in the literature from 0.4 % to 56 % . - pubmed
Numerous factors that may be associated with the risk of ORN include treatment - related variables ( for example , total radiotherapy dose , biologically effective dose , photon energy , brachytherapy dose rate , combination of external beam irradiation and interstitial brachytherapy , field size , fraction size , volume of the mandible irradiated with a high dose ) , patient - related variables ( like deep parodontitis , pre - irradiation bone surgery , bad oral hygiene , alcohol and tobacco abuse , bone inflammation , dental extraction after radiotherapy ) and tumour - related factors ( tumour size or stage , proximity of the tumour to bone , anatomic tumour site ) . - pubmed
Anxiety disorders in children : intervention strategies for the primary care setting . - pubmed
Ginkgo biloba for the prevention and treatment of cardiovascular disease : a review of the literature . - pubmed
We reported a 29 - year - old woman with McArdle ' s disease accompanied with insulin resistance . - pubmed
Phencyclidine ( PCP ) is a drug of abuse that has rewarding and dysphoric effects in humans . - pubmed
Pharmacological treatment of motor features is disappointing except for a transient L - Dopa response in a minority of MSA - P patients . - pubmed
CONCLUSION : Both Lactobacillus salivarius 433118 and Bifidobacterium infantis 35624 significantly attenuate colitis in this murine model . - pubmed
However , using this protocol , it is still difficult to induce long - term regression in established tumor - bearing mice . - pubmed
Removal of one of these cellular components during vaccination resulted in failure to completely cure tumor - bearing mice . - pubmed
Two patients had unilateral grade 1 sacroiliitis , one patient grade 4 sacroiliitis , and one patient bilateral grade 2 sacroiliitis . - pubmed
CONCLUSION : The results of the initial study showed that long term treatment with lymecycline in patients with acute ReA decreased the duration of arthritis in those with Chlamydia trachomatis triggered ReA , but not in other patients with ReA. - pubmed
Ten years after the acute arthritis one patient had developed AS , and three had radiological sacroiliitis , three patients had radiological changes at peripheral joints . - pubmed
[ Ammonium content in leaves in Fusarium infection of melons ] . - pubmed
[ Preoperative and postoperative studies on blood coagulation components and on fibrinolytic activity in surgical patients ] . - pubmed
Specific measurements were taken on both sides of 26 Turkish human male skulls , none of which showed any obvious pathology or trauma . - pubmed
PURPOSE : The advent of endovascular prostheses to treat descending thoracic aortic lesions offers an alternative approach in patients who are poor candidates for surgery . - pubmed
METHODS : We conducted a retrospective review of 60 emergent and high - risk patients with thoracic aortic aneurysms ( TAAs ) and dissections treated with endovascular prostheses over 4 years under existing investigational protocols or on an emergent compassionate use basis . - pubmed
Thirty - five patients received treatment of TAAs . - pubmed
Twenty - four patients with aortic dissections ( 16 acute , 8 chronic ) also received treatment . - pubmed
Eight of the patients with acute dissection had active hemorrhage at the time of treatment . - pubmed
One patient underwent surgical repair of a retrograde ascending aortic dissection after endograft placement . - pubmed
CONCLUSION : Although significant morbidity and mortality remain , endovascular repair of descending TAAs and dissections in patients at high - risk patients can be accomplished with acceptable outcomes compared with traditional open repair . - pubmed
Evaluation of brainstem auditory potential in brucellosis patients with and without neurological involvement . - pubmed
Twenty - two patients with brucellosis without neurologic involvement and seven patients with neurobrucellosis were included . - pubmed
Patients who had neurologic involvement did not show any abnormalities in their BAEPs recording . - pubmed
This study suggests that patients with brucellosis who are in the acute phase of the disease with or without neurological involvement may have normal BAEPs . - pubmed
BAEPs do not seem to be a sensitive method for central nervous system involvement of brucella patients in the acute phase of the disease . - pubmed
BACKGROUND & amp ; AIMS : Although hepatitis C virus kinetics and immune determinants during primary infection have been described , the virus - host interplay is not fully understood . - pubmed
Effect of Mornidae Radix extracts on experimental osteoporosis in sciatic neurectomized mice . - pubmed
The preventive and therapeutic effects of aqueous extracts of Mornidae Radix ( MR ) were observed in sciatic neurectomized mice , a disused osteoporotic model . - pubmed
One woman chose vacuum aspiration for termination of the abortion on day 3 of the induced bleeding . - pubmed
In this multicentre , placebo - controlled , 16 - week trial , the efficacy and safety of oxcarbazepine monotherapy in patients with neuropathic pain of diabetic origin was evaluated . - pubmed
Eligible patients had a 6 - month to 5 - year history of neuropathic pain symptoms of diabetic origin and a pain rating of & gt ; or = 50 units on the visual analogue scale ( VAS ) . - pubmed
Patients on oxcarbazepine were awakened less frequently due to pain than patients on placebo . - pubmed
These observations suggest that oxcarbazepine monotherapy , pending additional trials , may be efficacious and may provide clinically meaningful pain relief in patients with neuropathic pain of diabetic origin . - pubmed
BACKGROUND : Osteosarcoma ( OSA ) is the most frequent type of primary malignant bone tumor and is apt to occur in children and young adults . - pubmed
METHODS : We detected OC mRNA expression by RNA in situ hybridization in OSA and OSPM samples from patients , and tested OC promoter transcriptional activity in OSA and non - OSA cell lines . - pubmed
[ Effects of norcantharidin on angiogenesis of human gallbladder carcinoma and its anti - angiogenic mechanisms ] . - pubmed
OBJECTIVE : To investigate the effects of norcantharidin ( NCTD ) on angiogenesis of human gallbladder carcinoma and its anti - angiogenic mechanisms . - pubmed
METHODS : Human gallbladder carcinoma cells of the line GBC - SD were cultured . - pubmed
The short - term precision of QUS was investigated with regard to BMI of healthy individuals and with regard to the level of disease activity in patients suffering from RA . - pubmed
The patients with RA were divided into two BMI groups as well as into low and advanced disease activity groups . - pubmed
Pathogenesis , laboratory diagnosis , and clinical implications of erythrocyte enzyme deficiencies in dogs , cats , and horses . - pubmed
Animals with pyruvate kinase ( PK ) or phosphofructokinase ( PFK ) deficiencies have shortened erythrocyte life spans and regenerative anemia . - pubmed
PK - deficient dogs ( but not PK - deficient cats ) develop progressive myelofibrosis and osteosclerosis of bone marrow and hemochromatosis and cirrhosis of the liver . - pubmed
PFK - deficient dogs have sporadic episodes of hyperventilation - induced intravascular hemolysis and hemoglobinuria . - pubmed
Cytochrome b5 reductase ( Cb5R ) deficiency in dogs and cats results in persistent methemoglobinemia and cyanotic mucous membranes . - pubmed
Horses with erythrocyte flavin adenine dinucleotide ( FAD ) deficiency have both eccentrocytosis ( attributable to severe deficiency in glutathione reductase activity ) and methemoglobinemia ( attributable to Cb5R deficiency ) ; the dual enzyme deficiency occurs because FAD is a required cofactor for both enzymes . - pubmed
Erythrocyte enzyme deficiencies do not usually shorten life expectancy , except for PK - deficient dogs and potentially PFK - deficient dogs during a hemolytic crisis . - pubmed
Although enzyme deficiencies are rare causes of anemia and methemoglobinemia , the ability to diagnose deficient animals allows for the possibility of eliminating these undesirable traits in future breeding . - pubmed
Chiropractic management of cow 's milk protein intolerance in infants with sleep dysfunction syndrome : a therapeutic trial . - pubmed
OBJECTIVE : In addition to the more usual cutaneous , gastrointestinal , and respiratory problems , infants with cow 's milk intolerance ( CMI ) may present with a disturbed sleep pattern . - pubmed
Infants fulfilling a clinical screening protocol for CMI were selected for a therapeutic trial . - pubmed
PATIENTS AND METHODS : Thirty - one female patients with operable breast cancer consented to immediate breast reconstruction during the period from June 1998 to December 2000 . - pubmed
In the pedicled flap group , two patients ( 10.5 % ) experienced partial flap loss and fat necrosis was detected in two other patients . - pubmed
For the free flap group , two patients ( 13.3 % ) developed complete flap loss , but none suffered fat necrosis . - pubmed
None of the patients in both groups developed abdominal wall hernia , but abdominal wall weakness was evident in eight patients in the pedicled flap group that gradually improved over 2 - 3 months . - pubmed
The induction of complete transformation of the human breast epithelial cell MCF-10F in vitro confirms the carcinogenicity of E(2 ) , supporting the concept that this hormone could act as an initiator of breast cancer in women . - pubmed
OBJECTIVES : In the current study we describe and characterize a novel ovine model of biventricular hypertrophy and heart failure and evaluate the role of selected cardiac transcription factors in the regulation of cardiac gene expression during pathologic hypertrophy in vivo . - pubmed
CONCLUSION : The shunted neonatal lamb is a valid , novel model of pathologic biventricular hypertrophy . - pubmed
To define this relationship , we assessed a large cohort of women following first recognized obstetric anal sphincter injury . - pubmed
STUDY DESIGN : In all , 500 consecutive women were studied at 3 months following primary repair of a first recognized obstetric anal sphincter injury sustained during vaginal delivery . - pubmed
MATERIAL AND METHOD : the study complied 36 children aged 4 months - 3 years treated in the Department of Children Allergology , Gastroenterology and Nutrition because of atopic dermatitis . - pubmed
It seems that animal hair and food allergens are mainly responsible for development of atopic dermatitis . - pubmed
The long - term outcome of patients with bleeding gastric varices after balloon - occluded retrograde transvenous obliteration . - pubmed
BACKGROUND : The purpose of our study was to evaluate the long - term outcome and complications of balloon - occluded retrograde transvenous obliteration ( B - RTO ) in patients with hemorrhage from gastric fundal varices . - pubmed
METHODS : Thirty - four consecutive patients with bleeding from gastric varices who were treated with B - RTO were enrolled in this study between December 1994 and September 2005 ( urgent cases , n = 12 ; elective cases , n = 22 ) . - pubmed
RESULTS : Complete obliteration was achieved in 31 of 34 ( 91 % ) patients with an acute bleeding episode . - pubmed
Gastric varices disappeared in all patients with complete obliteration during the treatment . - pubmed
Variceal rebleeding from esophageal varices occurred in three patients . - pubmed
The patients with worsening esophageal varices were successfully treated with an endoscopic procedure . - pubmed
MATERIAL AND METHODS : We reviewed the records of all PC patients who were potential candidates for a surgical staging procedure prior to treatment with intent to cure at Skejby Sygehus , Denmark between 1996 and 2004 . - pubmed
RESULTS : A total of 50 patients ( 22 % ) had lymph node metastases ( pN1 ) and only 12 of these cases ( 24 % ) were detected by imaging . - pubmed
The 12 patients identified by imaging had clinically advanced and pathologically aggressive cancers . - pubmed
Forty percent of patients with end stage renal disease wait more than 2 years for renal transplant . - pubmed
The reconstructed kidney was allotransplanted to a 62 - year - old man with end stage renal disease . - pubmed
The cognitive performance of a group of 24 patients recovering from TBI ( with a mean Glasgow Coma Scale score in the severely impaired range ) was measured at 2 and 5 months postinjury . - pubmed
To explain this mechanism , an experimental study has quantified that the bone marrow cell transplantation decreases the number of inflammatory cells and reduces the fibrosis area in chagasic mice . - pubmed
METHODS : Retrospective analyses were performed on eight patients with metopic synostosis treated at St. Mary 's Hospital ( Seoul ) during 2002 - 2006 . - pubmed
Two patients had concomitant bicoronal synostosis requiring coronal suture resection with anterior two - thirds calvarial reconstruction . - pubmed
SUBJECTS : Individuals with long - standing hypopigmented cervicofacial scars . - pubmed
Outcome measures included observer and patient subjective assessment of the scar , and objective evaluation of the erythema and melanin content of the scar and the surrounding skin . - pubmed
METHODS : The case notes of 107 diabetics with proliferative retinopathy undergoing indirect PRP were reviewed retrospectively , and compared with the UK National Diabetic Retinopathy Laser Treatment Audit . - pubmed
One patient with underlying neurotrophic keratopathy developed a persistent epithelial defect . - pubmed
PATIENTS : Nineteen patients with gastric superficial lesions ( 15 - 30 mm ) , with high - grade ( n = 15 ) or low - grade ( n = 4 ) noninvasive epithelial neoplasias , in the antrum ( n = 12 ) , incisura angularis ( n = 2 ) , body ( n = 3 ) , and cardia ( n = 2 ) . - pubmed
In this review , the pathophysiology of smoke inhalation injury , along with the characteristics found in clinical settings , common animal models , current treatment methods and future potential therapeutics are discussed . - pubmed
Using the Phaseolus vulgaris system , we have addressed the questions concerning accumulation of sublimons , the role of recombination in their maintenance and selective amplification during SSS . - pubmed
Providing an acceptable quality of life for patients after reconstruction of mandibular segmental defects is challenging because the surgical techniques available have limitations . - pubmed
Four patients with severe mandibular osteoradionecrosis underwent a two - stage reconstruction . - pubmed
We describe one patient with conversion dumbness and another with conversion paraplegia . - pubmed
Bet 1 : steroids for patients with vestibular neuronitis . - pubmed
Genetic analyses of Drosophila CNS neoplasia , mouse glioma models , and human glioma tissues have revealed a link between increased NSC self - renewal and brain tumorigenesis . - pubmed
Furthermore , data from various rodent models of malignant brain tumors have provided compelling evidence that multipotent NSCs and lineage - restricted neural progenitor cells ( NPCs ) could be the cell origin of brain tumors . - pubmed
OBJECTIVE : In cats , spike - wave ( SW ) seizures have been observed to emerge from cortical slow oscillations ( CSOs ) and spindles in sleep . - pubmed
We examined a patient 's generalized SW seizures that appeared to emerge from CSOs in sleep . - pubmed
SIGNIFICANCE : The correlation of SW seizures with CSOs in animal studies may be observed in humans as well , providing clues to the pathology of arousal regulation in some cases of nocturnal epilepsy . - pubmed
The study we conducted showed that the ME is present in geriatric patients with MCI ; the influence on spatial - temporal abilities remains constant in time if the stimulation is maintained . - pubmed
Subthalamic lesion in the primate . - pubmed
Relationship between serum acute - phase proteins and high disease activity in patients with rheumatoid arthritis . - pubmed
PURPOSE : The aim of this study was to assess the relationship between serum acute - phase proteins and high disease activity evaluated by activity score ( DAS28 ) in patients with rheumatoid arthritis . - pubmed
MATERIAL / METHODS : Studies were carried out on 27 females with RA and 32 control women . - pubmed
RESULTS : The serum levels of acute - phase proteins changed in RA patients . - pubmed
Of the 129 patients assessed , the rate of adult ADHD was 27.9 % . - pubmed
In response to injury , the function of the adult mammalian central nervous system ( CNS ) is repaired by angiogenesis and neurogenesis . - pubmed
PATIENTS AND METHODS : Thirty BPH patients complaining of erectile dysfunction along with moderate - to - severe lower urinary tract symptoms ( LUTS ) who underwent transurethral resection of the prostate ( TURP ) were enrolled in the present study . - pubmed
OBJECTIVE : To simulate and assess the clinical effect of intracoronary infusion of bone marrow mononuclear cells or peripheral endothelial progenitor cells on myocardial reperfusion injury in mini - swine model . - pubmed
METHODS : Twenty - three mini - swine with myocardial reperfusion injury were used as designed in the study protocol . - pubmed
Crude extracts of Agaricus brasiliensis induce apoptosis in human oral cancer CAL 27 cells through a mitochondria - dependent pathway . - pubmed
However , the exact anticancer mechanisms of ABM on human oral cancer cells are still unclear . - pubmed
Phase II trial of intraperitoneal cisplatin combined with intravenous paclitaxel in patients with ovarian , primary peritoneal and fallopian tube cancer . - pubmed
: Although only 52 % of patients were able to complete 6 cycles of cisplatin - based IP chemotherapy , significant reductions in cisplatin - related metabolic toxicity and catheter - related complications were noted . - pubmed
Here , we use two - photon imaging to monitor the fine structure of inhibitory neurons in mouse visual cortex after deprivation induced by retinal lesions . - pubmed
Recent animal studies have clarified mechanisms leading to the ototoxicity induced by these agents , at least in part . - pubmed
In this review , recent findings from animal studies regarding the ototoxicity induced by aminoglycosides , cisplatin , and NSAIDs are summarized . - pubmed
The in vitro activities of inhibiting pig platelet aggregation induced by PAF , ADP , and AA , as well as the in vivo anti - thrombotic activities of inhibiting rat thrombosis of these aromatized derivatives were generally higher than that of N -( 1 - methyl - beta - tetrahydrocarboline-3 - carbonyl )- N '-( aminoacid - acyl )- hydrazines . - pubmed
Analysis and perspective : A randomized , open - label , comparative crossover handling trial between two durable pens in patients with type 1 or 2 diabetes mellitus . - pubmed
Pap smears were prepared from patients presenting with complaints like vaginal discharge , post - coital bleeding , inter - menstrual bleeding , dyspareunia , and pain lower abdomen . - pubmed
Mean age of the patients with diagnosis of LSIL was 32.3 years and for HSIL , it was 40.5 years . - pubmed
The mean age of the patients with invasive carcinoma was 57 years . - pubmed
Neutrophils isolated from AMI patients showed two - fold higher ROS generation compared with cells from healthy donors , especially in the lucigenin - enhanced luminescence model , which suggests intensive O2- generation . - pubmed
Resting electrocardiogram predicts mortality in postmenopausal women with coronary heart disease or with risk factors for coronary heart disease . - pubmed
RESULTS : During a median follow - up of 5.6 years , 500 women sustained coronary death . - pubmed
Semantic priming in remitted patients with bipolar disorder . - pubmed
The present study aimed to investigate semantic priming in patients with bipolar disorder ( BD ) . - pubmed
Severe SR was encountered in 24 ( 44 % ) patients with SRs . - pubmed
The median level of sBT in children with SRs ( median , interquartile range ) [ 4.2 mug / l ( 3.6 - 4.9 ) ] was significantly higher than in children with LLRs [ 3.1 mug / l ( 2.5 - 4.0 ) ] and healthy control subjects [ 2.9 mug / l ( 2.3 - 3.4 ) ] ( P & lt ; 0.001 ) . - pubmed
Determination of sBT levels may help clinicians to identify patients under risk of severe SRs and optimal and timely use of therapeutic interventions in children with venom allergy . - pubmed
Human prion diseases : progress in clinical trials . - pubmed
In the late 1940s , epidemics of antibiotic - resistant strains of Staphylococcus aureus began to plague postpartum nurseries in hospitals across the United States . - pubmed
The exploration of these measures reveals a shift in infection control policy as hospitals , faced with the failure of antibiotics to slow S. - pubmed
Showcasing the need for widespread epidemiologic surveillance , ultimately manifesting itself in specialized " hospital epidemiology " training promoted in the 1970s , the challenges faced by hospital nurses in the 1950s prove highly relevant to the continued struggle with methicillin - resistant Staphylococcus aureus ( MRSA ) and other resistant nosocomial infections . - pubmed
A Pilot Study of Fluorodeoxyglucose Positron Emission Tomography Findings in Patients with Phenylketonuria before and during Sapropterin Supplementation . - pubmed
1 ) To evaluate brain glucose metabolism with FDG - PET imaging in phenylketonuria ( PKU ) patients before and 4 months after sapropterin therapy ; 2 ) to evaluate neurodevelopmental changes , blood Phe levels and dietary Phe tolerance before and after sapropterin therapy ; 3 ) to generate pilot data to assess the feasibility of evaluating brain glucose metabolism with FDG - PET imaging and to explore potential trends resulting from the administration of sapropterin therapy . - pubmed
METHODS : We enrolled 5 subjects , ranged in age from 22 years to 51 years , with PKU . - pubmed
CONCLUSIONS : Further studies with a larger sample size are needed to confirm the above changes in both sapropterin non - responsive and responsive PKU patients . - pubmed
RESULTS : A quantitative PCR ( qPCR ) approach was used to determine the copy numbers of two endogenous double stranded DNA plasmids : pZMO1A ( 1,647 bp ) and pZMO7 ( pZA1003 ; 4,551 bp ) within the NCIMB 11163 strain of Z. - pubmed
METHODS : Ventriculoarterial coupling was assessed before Fontan completion in 32 patients with hypoplastic left heart syndrome ( 19 modified Blalock - Taussig and 13 Sano shunts at stage 1 ) . - pubmed
In particular , 5/16 patients with resistance carried viral strains with SDRMs to multiple ARV classes , hence one - third of resistant strains were multiclass resistant , including non - B strains . - pubmed
Metabolic disturbances such as anorexia nervosa , obesity , and diabetes mellitus have clinically important consequences on human reproduction . - pubmed
Both groups engaged similar neural networks during processing of emotional music , and individuals with ASD rated emotional music comparable to the group of neurotypical individuals . - pubmed
All registered deaths were HIV - related . - pubmed
Of 55 patients with subsequent HIV - RNA measurements , only 12 of 30 ( 40 % ) patients with VF achieved virological suppression , compared to 20 of 25 ( 80 % ) patients with VR ( p = 0.003 ) . - pubmed
UNLABELLED : Development of temozolomide ( TMZ ) resistance contributes to the poor prognosis for glioblastoma multiforme ( GBM ) patients . - pubmed
SGT-53 significantly chemosensitized TMZ - sensitive human GBM cell lines ( U87 and U251 ) , in vitro and in vivo . - pubmed
METHOD : In an A / B single case experimental design , a patient completed five daily ideographic measures of anxiety and depression across baseline and treatment and the HADS at five time points over time , including 3 - month follow - up . - pubmed
RESULTS : A total of 761 symptomatic patients ( 40.1 % with transient ischemic attack [ TIA ] , 21.3 % with amaurosis fugax , and 38.6 % with ischemic stroke ) were included , with an overall peri - operative stroke and death rate of 3.3 % . - pubmed
Given the fact that ruptured plaques with neurological symptoms carry the highest risk of a recurrent ischemic event in the first 2 days , treating patients as soon as possible to offer the highest benefit in stroke prevention is recommended . - pubmed
BACKGROUND : The prevalence of human papillomavirus ( HPV ) infection and the distribution of different HPV genotypes vary greatly within different geographical and ethnic populations , especially in Asia . - pubmed
The HPV infection data based on regional population are extremely important for researchers to develop new efficient HPV screening assays and estimate the effect of vaccines on preventing from cervical cancer . - pubmed
The top 6 HPV genotypes were HPV16 ( 1.5 % ) , HPV52 ( 1.2 % ) , HPV58 ( 1.0 % ) , HPV18 ( 0.7 % ) , HPV45 ( 0.5 % ) , and HPV6 ( 0.5 % ) , accounting for 69.7 % of all detected HPV infection types . - pubmed
Infection with single genotype HPV ( 6.2 % in all ; 85.7 % in HPV - positive women ) was more frequent than infection with multiple HPV ( 1.0 % and 14.3 % respectively ) . - pubmed
In this population , HPV infection prevalence was 7.3 % , and genotypes HPV16 , HPV52 , and HPV58 showed a relatively high prevalence . - pubmed
aureus ( MSSA ) accounted for 64.2 % ( 68/106 ) of the gram - positive infections . - pubmed
[ Compound K suppresses myeloid - derived suppressor cells in a mouse model bearing CT26 colorectal cancer xenograft ] . - pubmed
CONCLUSION : C - K can suppress the immunosuppresive effect of MDSCs to inhibit tumor cell proliferation in mice , which suggests a new strategy of tumor therapy by targeting MDSCs . - pubmed
Intrahepatic transplantation of adipose - derived stem cells attenuates the progression of non - alcoholic fatty liver disease in rats . - pubmed
In the present study , adipose tissue - derived stem cells ( ADSCs ) , which were isolated from the adipose tissues of Sprague - Dawley rats , were transplanted into the liver of high - fat - diet - induced NAFLD rats via the portal vein to attenuate the disease progression of NAFLD . - pubmed
METHODS : We consecutively enrolled 60 ischemic stroke patients newly started on NOAC treatment and obtained blood samples at 6 prespecified time points . - pubmed
CONCLUSIONS : If anti - Xa test is not available , we propose the use of the CoaguChek POCT to guide thrombolysis decisions after individual risk assessment in rivaroxaban - treated patients having acute ischemic stroke . - pubmed
In this observational retrospective single centre study , 28 CML patients with ACAs at diagnosis and during TKI treatment were included . - pubmed
In this report , we describe the clinical courses of 2 lung transplant recipients with systemic sclerosis who experienced severe and prolonged barium - impaction ileus after insertion of a percutaneous gastrojejunal feeding tube . - pubmed
pneumophila strains were much higher than those in reference non - L. - pubmed
pneumophila strains were similar to those in environmental L. - pubmed
A 33 - year - old woman presented with an unusual subglottic bulging mass accompanied by prolonged cough and wheeze . - pubmed
The patient remains well and free of recurrence or metastasis . - pubmed
BACKGROUND : Periacetabular osteotomy is an excellent intervention for patients at early - stage osteoarthritis , but surgical education for this technique is more difficult than that for total hip arthroplasty . - pubmed
Perioperative and postoperative complications were observed in 14 patients of the trainee group and 3 patients of the instructor group , which were significantly different ( p = 0.0061 ) . - pubmed
Higher early adulthood intake of fruits and vegetables rich in alpha carotene was associated with lower risk of premenopausal breast cancer . - pubmed
For individual fruits and vegetables , greater consumption of apple , banana , and grapes during adolescence and oranges and kale during early adulthood was significantly associated with a reduced risk of breast cancer . - pubmed
OBJECTIVE : To introduce a new bone defect model based on the anatomical measurement of radius and ulna in rabbits for offering a standard model for further tissue engineering research . - pubmed
RESULTS : Blood vessel injury ( 1 rabbit ) , tendon injury ( 2 rabbits ) , postoperative hematoma ( 1 rabbit ) , and infection ( 1 rabbit ) occurred in group A , postoperative infection ( 1 rabbit ) in group C , and no postoperative complications in group B ; the complication rate of group A ( 50 % ) was significantly higher than that of groups B ( 0 % ) and C ( 10 % ) ( P<0.05 ) . - pubmed
OBJECTIVE : To collect and summarize demographic , clinical , laboratory and radiologic characteristics , as well as management and follow - up data , of patients diagnosed with ovarian vein thrombosis . - pubmed
METHODS : A multicenter retrospective review of all patients diagnosed with ovarian vein thrombosis between January 2000 and May 2015 at three university hospitals . - pubmed
Median duration of anticoagulation treatment tended to be longer among patients with non - pregnancy related OVT ( 6months [ 3 - 14 ] vs. 3months [ 3 - 6 ] , P=0.1 ) . - pubmed
Injection of miR-10b mimics into tumor cell xenografts also promoted xenograft growth in nude mice . - pubmed
BACKGROUND : This is a retrospective chart review to evaluate the efficacy of the addition of vorinostat to lenalidomide and dexamethasone in patients with multiple myeloma relapsed / refractory to lenalidomide and dexamethasone . - pubmed
CONCLUSION : These observations demonstrate that the addition of vorinostat to patients with lenalidomide- and dexamethasone - refractory multiple myeloma was associated with moderate response and was well - tolerated , warranting further assessment in a larger prospective study . - pubmed
METHODS : This was a retrospective observational cohort study on patients with adenocarcinoma of the pancreatobiliary system who underwent diagnostic core needle biopsy or surgical resection at a tertiary referral center . - pubmed
Among patients who underwent surgical resection of their primary tumor with curative intent , the intestinal type showed an adjusted hazard ratio of 0.19 for overall survival ( 95 % confidence interval 0.05 - 0.72 ; p value = 0.014 ) compared to the extrahepatic pancreatobiliary type . - pubmed
Streptozotocin ( STZ)-induced type 1 diabetic rats were subjected to MI / R surgery with or without perioperative administration of DATS ( 40 mg / kg ) . - pubmed
However , the link between IGF-1 and the occurrence of hearing impairment is untested in population - based studies of humans . - pubmed
The aims of this study were to determine carbapenem resistance mechanisms , molecular epidemiological relationship , clinical impact , and patient outcome of carbapenem - resistant Pseudomonas aeruginosa ( CRPA ) infections . - pubmed
The population included 26 patients with pseudotumors diagnosed by two radiologists using the method described by Matthies et al . - pubmed
The f element represents an instance of bacteria - to - animal HGT that has occurred so recently that it was possible to infer the donor ( feminizing Wolbachia closely related to the wVulC Wolbachia strain of A. - pubmed
We describe a case involving a 61 - year - old woman who was suffering from COA with a concomitant arch aneurysm and coronary artery disease . - pubmed
Dr Jaffe summarizes these alternatives , patient selection , success rates , and posttreatment recurrence . - pubmed
A 32 - year - old man , born out of non - consanguineous union , presented with generalised tonic - clonic seizures and myoclonus since 17 years of age . - pubmed
Lower urinary tract autonomic dysfunction evaluation in spinal cord injury patients : an applied example . - pubmed
Large strongyles can cause death of horses while cyathostomins ( small strongyles ) have shown increased resistance to anthelmintics worldwide . - pubmed
Clinical Impact of 5 Years of Liraglutide Treatment on Cardiovascular Risk Factors in Patients with Type 2 Diabetes Mellitus in a Real - Life Setting in Italy : An Observational Study . - pubmed
RESULTS : Overall , 103 patients ( age 59.0 + - 7.9 years , diabetes duration 10.4 + - 6.8 years ) were involved in the study . - pubmed
Brain abscess and bronchopneumonia caused by Acinetobacter baumannii in a 2 - year - old female sheep . - pubmed
PURPOSE OF REVIEW : The leading cause of death in both chronic kidney disease ( CKD ) and renal transplant patients is cardiovascular events . - pubmed
PTx - DM has been associated with a negative impact on patient and graft outcomes and survival . - pubmed
RECENT FINDINGS : Individuals who develop PTx - DM are usually prone to this condition prior to and/or after developing CKD . - pubmed
Severe vemurafenib - induced photosensitivity in a 6 - year - old boy . - pubmed
While photosensitivity has been well described as one of these manifestations , we report a case of a 6 - year - old boy on vemurafenib who developed a severe blistering sunburn after only two 30 - minute episodes of sun exposure . - pubmed
Effectiveness of influenza and pneumococcal polysaccharide vaccines against influenza - related outcomes including pneumonia and acute exacerbation of cardiopulmonary diseases : Analysis by dominant viral subtype and vaccine matching . - pubmed
RESULTS : Among 2,119 enrolled cases , 1,302 ( 61.4 % ) and 871 ( 41.1 % ) received the influenza vaccine and 23 - valent pneumococcal polysaccharide vaccine ( PPV23 ) , respectively . - pubmed
During an A / H3N2 - dominant season with poor influenza vaccine effectiveness ( 2014 - 2015 season ) , neither the influenza vaccine nor PPV23 showed significant effectiveness against pneumonia or acute exacerbation of cardiopulmonary diseases . - pubmed
We developed a multiplex PCR and multi - color fluorescent in situ hybridization ( m - FISH ) protocols for simultaneous detection of CD - associated pathogens including Mycobacterium avium subspecies paratuberculosis ( MAP ) , Klebsiella pneumoniae , and adherent - invasive Escherichia coli strain LF82 . - pubmed
LONG - TERM OUTCOMES AND PROGNOSTIC FACTORS IN PATIENTS WITH DIFFERENTIATED THYROID CARCINOMA AND BONE METASTASES . - pubmed
Objective : This institutional study sought to retrospectively evaluate disease progression and survival of patients with differentiated thyroid cancer ( DTC ) and bone metastases ( BM ) and to investigate variables predictive of better long - term outcomes . - pubmed
Methods : The Rabin Medical Center Thyroid Cancer Registry was searched for patients with bone - metastatic DTC . - pubmed
Variables including a patient 's gender and age , pathology of the thyroid tumor , and characteristics of BM were retrieved and analyzed in association with disease progression and mortality . - pubmed
Histopathology yielded papillary and follicular DTC in 40.6 % and 32.8 % of patients , respectively , and poorly / intermediately differentiated carcinoma in 26.6 % . - pubmed
Nineteen patients ( 29.7 % ) presented with multiple - site BM , of whom 15 ( 78.9 % ) had spinal metastases . - pubmed
Conclusions : Selected patients with bone - metastatic DTC may achieve fair long - term outcomes . - pubmed
This study included 113 patients with a confirmed diagnosis of type-2 DM . - pubmed
Among them , 18 patients did not have diabetic retinopathy ( DR ) , 71 had non - proliferative DR ( NPDR ) , and 24 had proliferative DR ( PDR ) . - pubmed
We suggest prompt ophthalmic evaluation in patients with systemic arteriosclerosis . - pubmed
RESULTS : Among 1938 patients ( mean age 70 + - 11 , 48 % female ) with ASCVD , the percentage on high - intensity statin therapy significantly increased over time : 24 % in 2013 , 34 % 2014 , 42 % 2015 , and 49 % 2016 ( P & lt ; .0001 ) . - pubmed
Materials and methods : This case - control study included 112 patients with " stroke of undetermined etiology " and 160 controls . - pubmed
Open - ended responses were widespread and often incorrect , specifically with regard to the human papillomavirus vaccine and routine testing for sexually transmitted infections . - pubmed
MATERIALS AND METHODS : Records of patients with VKC , who visited our tertiary centre from 1992 and 2009 , were reviewed and those with steroid - induced glaucoma were included in the study . - pubmed
RESULTS : Of the 4062 VKC subjects , 91 ( 157 eyes ) had steroid - induced glaucoma ( SIG ) , showing a prevalence of 2.24 % . - pubmed
Direct immunofluorescence is of limited utility in patients with low clinical suspicion for an oral autoimmune bullous disorder . - pubmed
CONCLUSIONS : In patients with a low clinical suspicion for an oral autoimmune bullous disorder , it is reasonable and more cost - effective to evaluate the lesion with routine histology alone . - pubmed
OBJECTIVE : The aim of the article is to present the clinical observation of a successfully treated giant aneurysm of the pericallosal artery in a 58 - year - old man , and also analyze the publications on distal cerebral aneurysms . - pubmed
MATERIAL AND METHODS : The data of a patient hospitalized with a suspected tumor of the left brain hemisphere spreading to the left lateral ventricle is presented . - pubmed
The patient underwent aneurysm treping - cliping with dissection of the aneurysm sac . - pubmed
Biofeedback fixation training method for improving eccentric vision in patients with loss of foveal function secondary to different maculopathies . - pubmed
METHODS : Sixty - seven consecutive patients with bilateral central vision loss , poor FS and visual acuity ( VA ) lower than 0.3 LogMAR were recruited for BFT with microperimeter . - pubmed
aureus that result in human infection . - pubmed
Physical exercise attenuates cognitive decline and reduces behavioural problems in people with mild cognitive impairment and dementia : a systematic review . - pubmed
QUESTIONS : What is the effect of physical exercise on cognitive decline and behavioural problems in people with mild cognitive impairment ( MCI ) or dementia ? - pubmed
PARTICIPANTS : People with MCI or dementia as their primary diagnosis . - pubmed
CONCLUSION : Physical exercise can reduce global cognitive decline and lessen behavioural problems in people with MCI or dementia . - pubmed
Chemotherapy options versus " novel " therapies : how should we treat patients with malignant pleural mesothelioma . - pubmed
Today there are several options for the treatment of patients with malignant pleural mesothelioma ( MPM ) . - pubmed
Triazolam - induced Mania in a Patient with Bipolar I Disorder Following a Dental Procedure . - pubmed
Effects of high fat diet - induced obesity on vitamin D metabolism and tissue distribution in vitamin D deficient or supplemented mice . - pubmed
Background : Vitamin D deficiency has been often observed in obese persons . - pubmed
Data was extracted for type of radiotherapy , number of patients , type of PEG - hydrogel used , mean prostate - rectum separation , rectal dosimetry , acute and late GI toxicity , procedure - related complications and the technique used for hydrogel insertion . - pubmed
Improvement Effect of 5 - Aminolevulinic Acid on Hyperlipidemia in Miniature Schnauzer Dogs : An Open Study in 5 Cases of One Pedigree . - pubmed
This is the first study to examine the long - term effect of 5 - aminolevulinic acid mainly on serum lipoproteins in dogs with hyperlipidemia . - pubmed
Cryptococcus neoformans is an opportunistic fungal pathogen , which is a frequent cause of a life - threatening meningitis in immunocompromised individuals . - pubmed
The new assay was used to evaluate SARS - CoV-2 antibodies in serum from individuals with a broad range of COVID-19 symptoms , including intensive care unit ( ICU ) patients , health care workers ( HCWs ) , and convalescent plasma donors . - pubmed
Menthol cigarette use in substance use disorder treatment before and after implementation of a county - wide flavoured tobacco ban . - pubmed
INTRODUCTION : This study examined the impact of a San Francisco City and County ban on all flavoured tobacco products , including menthol cigarettes , among clients in residential substance use disorder ( SUD ) treatment . - pubmed
Notably , Radium-4 TCR + T cells also significantly reduced tumor growth and improved survival in a xenograft mouse model . - pubmed
Early and accurate detection of breast cancer plays an important role in improving the survival rates of patients . - pubmed
Chaetomium globosum Kunze is recognized as a potential biocontrol fungus against spot blotch of wheat caused by Bipolaris sorokiniana . - pubmed
globosum strain Cg2 during interaction with B. - pubmed
Venous Thrombosis and Thrombocyte Activity in Zebrafish Models of Quantitative and Qualitative Fibrinogen Disorders . - pubmed
Venous thrombosis occurs in patients with quantitative and qualitative fibrinogen disorders . - pubmed
Injury - induced thrombosis in zebrafish larvae has been used to model human coagulopathies . - pubmed
We aimed to determine whether zebrafish models of afibrinogenemia and dysfibrinogenemia have different thrombotic phenotypes . - pubmed
Peanut smut caused by Thecaphora frezii is a severe fungal disease currently endemic to Argentina and Brazil . - pubmed
Linkage of chloroquine resistance in Plasmodium berghei to infection of immature erythrocytes of mice . - pubmed
Problem areas both in staging and in general management of patients with Hodgkin ' s disease are emphasized . - pubmed
In ultrathin sections and negatively stained isolates from protoplasts of a strain of Saccharomyces cerevisiae showing abnormal morphology and degeneration phenomena the presence of virus - like particles within the cells could be demonstrated . - pubmed
The connective tissue from Tenon 's capsule of 7 patients who underwent surgery for retinal detachment was studied ultrastructurally . - pubmed
The Tenon capsules of 6 children and of 2 aged patients without retinal problems were used as controls . - pubmed
In the aged patients with retinal detachment , the collagen fibrils showed marked variation of size and also abnormalities of shape in 4 out of 5 cases . - pubmed
Effects of endotoxic shock on diaphragmatic function in mechanically ventilated rats . - pubmed
Diaphragmatic function was investigated in mechanically ventilated rats during endotoxic shock ( group E , n = 18 ) and after saline solution injection ( group C , n = 8) . - pubmed
Rearrangements of the T - cell receptor ( TCR ) delta locus are observed in the majority of human B - cell precursor acute lymphoblastic leukemias ( ALL ) with a striking predominance of V delta 2(D)D delta 3 recombinations in common ALL ( cALL ) patients . - pubmed
Diuretics and arteriolar resistance and arterial compliance in human hypertension . - pubmed
Survival of heart failure patients with preserved versus impaired systolic function : the prognostic implication of blood pressure . - pubmed
The impact of impaired versus preserved systolic function on survival of patients with heart failure was investigated in 78 patients with decompensated heart failure . - pubmed
We conclude that the prognosis of patients with heart failure and preserved systolic function is more favorable than that of those with impaired function , and that blood pressure may have a differential prognostic meaning in the two groups . - pubmed
Tumor - bearing rats re - enter an active growth phase and double their body weight over age - matched controls 8 weeks after introduction of the tumor . - pubmed
Atrial myocytes from tumor - bearing animals showed a 3 - fold increase in the density of T - type Ca2 + current compared with cells from control animals , although the voltage dependency of activation and inactivation of T - type current was not altered . - pubmed
Effect of acarbose on carbohydrate and lipid metabolism in NIDDM patients poorly controlled by sulfonylureas . - pubmed
The ability of acarbose to lower plasma glucose concentration was studied in 12 patients with non - insulin - dependent diabetes mellitus ( NIDDM ) who were poorly controlled by diet plus sulfonylurea drugs . - pubmed
The addition of acarbose to patients with NIDDM not well controlled by sulfonylureas appears to have significant clinical benefit . - pubmed
No signs of damage to the cell membrane integrity , neither electrical ( appearance of a leakage current ) nor morphological ( surface blebs , loss of striation pattern and of rodlike shape in the isolated myocytes ) , accompanied the effects observed on ionic currents and action potential activity , supporting the hypothesis of a selective cardiotoxic action of B. - pubmed
Tobacco consumption was positively associated with gastric cancer in males ( odds ratio as the approximate relative risk = 2.8 ) , whereas alcohol consumption was not . - pubmed
Monocyte - derived macrophages ( M phi ) from cancer patients injected with low doses of Neocarzinostatin ( NCS , 500 units / day , three times a week ) 12 times produced significantly more superoxide ( O2 - ) than controls . - pubmed
[ Frequency of recurrence after 3 days of therapy of the first infection of the lower urinary tract segment in children ] . - pubmed
Sultamicillin ( SBTPC ) fine granules were given to 15 patients with respiratory tract infections at a dose of 375 mg 3 times a day . - pubmed
Positron emission tomography ( PET ) offers a unique opportunity for studying the cerebral biochemistry of cocaine abuse in humans . - pubmed
We present the clinical manifestations and details of treatment and outcome for eight patients with squamous cell cancer arising in the thyroid gland , which is a rare entity . - pubmed
All patients had advanced disease , with primary tumors invading adjacent structures ( the trachea , esophagus , and major vessels ) . - pubmed
In two patients , pulmonary metastases were also present . - pubmed
Two patients remained free of disease at last follow - up more than 4 years after gross total tumor resection and radical radiotherapy and were presumably cured . - pubmed
Patients with unresectable tumors are best managed by supportive measures only unless a truly effective chemotherapeutic regimen is developed for squamous cell cancer of the head and neck . - pubmed
To determine the natural history of myocardial infarction ( MI ) in the absence of angiographically significant ( no lesion greater than or equal to 50 % diameter stenosis ) fixed coronary artery disease ( CAD ) , clinical and angiographic data and late outcome were studied in 43 such patients . - pubmed
Mild fixed CAD , present in 38 patients ( 88 % ) , was more frequent in the artery supplying the MI zone ( p less than 0.01 ) . - pubmed
Filling defects or serial angiographic resolution of obstruction in the artery supplying the MI zone were present in 14 patients ( 33 % ) . - pubmed
At late follow - up , 14 major cardiac events occurred in 9 patients , including revascularization in 3 , recurrent MI in 6 and cardiac death in 5 . - pubmed
Of 35 patients undergoing catheterization within 1 year of the index MI , cumulative risk of a major cardiac event was 9 + /- 4 , 12 + /- 5 and 20 + /- 7 % at 3 , 19 and 37 months , respectively . - pubmed
[ Aggravating action of oxygen in light injury to the retina in the white rat ] . - pubmed
Germinated spores and vegetative cells both showed two phases of elimination from the hamster cecum -- an initial phase of rapid death that was not affected by antibiotic treatment followed by a phase of complete inhibition of multiplication . - pubmed
The resistivities of a Swarm murine basement membrane sarcoma and also surrounding tissue in BALB / c mice were determined . - pubmed
Methisazone increased the mortality from ectromelia in adjuvant - treated animals . - pubmed
Interactions of anti - inflammatory drugs in carrageenan - induced foot edema of the rat . - pubmed
During studies of the metabolism of disodium aurothiomalate in patients with rheumatoid arthritis we have found that its pharmaceutical preparation . - pubmed
[ Clinical pharmacokinetics of antihypertensive drugs and the treatment of hypertension with special reference to children ] . - pubmed
Pemphigus and pemphigoid in dog and man : comparative aspects . - pubmed
A review of canine pemphigus vulgaris , pemphigus vegetans , pemphigus foliaceus , pemphigus erythematosus , and bullous pemphigoid shows them to share many clinicopathologic similarities with their human counterparts . - pubmed
Because of their numerous analogies in clinical presentations , histopathologic and immunopathologic findings , and therapeutic results , canine and human pemphigus and pemphigoid may represent a valuable area for comparative dermatologic research . - pubmed
A 63 - year - old female on long - term , high - dose tamoxifen treatment for metastatic breast cancer developed bilateral intraretinal refractile opacities , lesions at the level of the retinal pigment epithelium , and cystoid macular oedema . - pubmed
In al five patients the safflower oil was effective in remitting the symptoms of neurotoxicity . - pubmed
Safflower oil was also effective in a patient with familial tremor . - pubmed
False positive latex agglutination test with Neisseria meningitidis ACYW135 in a patient with intracranial dermoid tumor . - pubmed
Apparent outbreaks of Clostridium difficile - associated diarrhea in horses in a veterinary medical teaching hospital . - pubmed
Intestinal colonization with toxigenic strains of Clostridium difficile was documented in 9 of 10 horses with acute onset diarrhea in a veterinary medical teaching hospital , whereas a similar isolate was detected in only 1 of 23 other horses without diarrhea in the hospital . - pubmed
One horse with diarrhea was infected simultaneously with both C. - pubmed
difficile isolates were detected in the feces of the 9 affected horses at the time of the outbreak of diarrhea . - pubmed
[ Melanoma in children : a case ] . - pubmed
INTRODUCTION : Melanoma is rare in children . - pubmed
DISCUSSION : The diagnosis of melanoma is difficult in children and is usually mistaken . - pubmed
All patients were assessed for their age , preoperative bladder capacity , preoperative postvoid residual , operative time , estimated blood loss , length of hospital stay , postoperative analgesia requirement , time required to resume a normal voiding pattern , complications , and recurrence rate of the SUI . - pubmed
CONCLUSIONS : Retropubic LBNS is a technically feasible surgical procedure for patients with anatomic SUI . - pubmed
Variants of hepatitis B virus ( HBV ) , hepatitis C virus ( HCV ) and of the hepatitis Delta virus ( HDV ) have been identified in patients both with acute and chronic infections . - pubmed
The exact contribution , however , of specific mutations to the pathogenesis and natural course of HBV , HCV or HDV infection , including the development of hepatocellular carcinoma , remains to be established . - pubmed
To examine whether structural changes in hepatocytes and/or sinusoidal areas contribute to the portal hypertensive state in non - alcoholic cirrhosis , a new method of morphometric analysis using a computer - aided color image analyzer was performed in 16 patients with non - alcoholic cirrhosis , which allowed quantitative evaluation of various morphometric parameters of sinusoids and hepatocytes . - pubmed
Nasal mupirocin ointment decreases the incidence of Staphylococcus aureus bacteraemias in haemodialysis patients . - pubmed
aureus bacteraemia in a haemodialysis unit was studied over 2 years ( 167.75 patient - years of follow - up ) during which nasal calcium mupirocin was used to eradicate nasal S. - pubmed
Currently , the high level of operability of patients with endometrial carcinoma makes this staging system a viable one , which will provide information about the need for additional treatment . - pubmed
FDG - PET in differentiating lymphoma from nonmalignant central nervous system lesions in patients with AIDS . - pubmed
We studied 11 individuals with AIDS and central nervous system ( CNS ) lesions with 18F - fluoro-2 - deoxyglucose ( FDG ) and positron emission tomography ( PET ) . - pubmed
FDG - PET may be useful in the management of AIDS patients with CNS lesions since high FDG uptake most likely represents a malignant process which should be biopsied for confirmation rather than treated presumptively as infectious . - pubmed
Partial kidney transplantation : a successful kidney transplantation in a child with severe cardiac failure by surgical mass reduction of an adult donor kidney . - pubmed
Effects of diencephalic lesions on approach responses and color preferences in quail . - pubmed
This empirical approach does not require a strong mathematical background and offers a relatively simple method of predicting the kinetics of anti - cancer drugs in patients from pre - clinical animal data . - pubmed
beta - Alanine protects against taurine and NaCl -- induced hypernatremia in the rat . - pubmed
Rats drinking a combination of taurine and hypertonic saline solution rapidly develop hypernatremia , but rats drinking either solution alone do not . - pubmed
This transformation system will enable us to breed commercial strains of P. - pubmed
Validation study of a central venous pressure - based protocol for the management of neurosurgical patients with hyponatremia and natriuresis . - pubmed
OBJECTIVE : We had previously suggested a protocol for the management of neurosurgical patients with hyponatremia and natriuresis that was based on their volume status as determined by actual blood volume measurements . - pubmed
All patients in that study were found to be hypovolemic or normovolemic and responded , within 72 hours , to salt and fluid replacement . - pubmed
In the present study , the validity of that protocol was tested using central venous pressure as the sole measure of volume status of patients with hyponatremia and natriuresis . - pubmed
METHOD : Twenty - five consecutive patients ( 26 cases ) who fulfilled the inclusion criteria typically used to diagnose the syndrome of inappropriate secretion of antidiuretic hormone were included in the study . - pubmed
Central venous pressure was used to classify patients as hypovolemic ( & lt ; 5 cm of water ) , normovolemic ( 6 - 10 cm of water ) , or hypervolemic ( & gt ; 11 cm of water ) . - pubmed
Hypovolemic patients were given fluids ( 50 ml / kg / d ) and salt ( 12 g / d ) . - pubmed
In addition , patients with anemia ( hematocrit , & lt ; 27 % ) were administered whole blood . - pubmed
No patient was hypervolemic . - pubmed
CONCLUSION : Hyponatremia with natriuresis in the neurosurgical setting responds to salt and fluid replacement guided by the patients ' volume status as determined by the central venous pressure . - pubmed
Compared to the outbred Wistar rat strain , the Fawn - hooded rat strain has several characteristics which suggest that the Fawn - hooded strain is hyperaroused . - pubmed
Fawn - hooded rats exhibit more freezing behavior in response to stress , have an increased preference for alcohol , develop adult onset hypertension , and have elevated urinary catecholamine levels . - pubmed
Finally , adrenal weights were significantly reduced in the Fawn - hooded rats while basal corticosterone levels were similar in the two strains , which suggests central hypoactivity of the hypothalamic - pituitary - adrenal axis in Fawn - hooded rats compared to Wistar rats . - pubmed
Helicobacter pylori infection is the most frequent infection in humans . - pubmed
Compared with younger patients , elderly patients with PSGN tend to have a high incidence of renal function impairment and anuria or prolonged oliguria . - pubmed
Efficacy of low - dose isotretinoin in patients with treatment - resistant rosacea . - pubmed
We report here the characterization of the in vitro ( in the presence of 6000 IU interleukin 2 ) expanded tumor - infiltrating lymphocyte ( TIL ) T - cell line PM2 - B2 derived from a patient with rapidly progressing and therapy - resistant head and neck melanoma . - pubmed
During infection with vesicular stomatitis virus ( VSV ) , host - cell mRNA synthesis is inhibited due to shut off of host - cell transcription . - pubmed
Furthermore , the correlation between brain structure and CMRO2 suggests that monitoring CMRO2 during the operation may be an outstanding way to investigate new strategies for neuroprotection designed to reduce cerebral damage in children undergoing correction of congenital cardiac defects . - pubmed
Inhaled nitric oxide ( NO ) was administered to 5 consecutive children with life - threatening status asthmaticus who required mechanical ventilation and did not respond to maximal medical management . - pubmed
A recommendation is included how to advise patients with Parkinson ' s disease treated with a dopamine agonist regarding the ability to drive . - pubmed
INTRODUCTION : What causes meningococcial diseases ( MD ) is a Gramm - negative diplococcus Neisseria meningitidis ( meningococcus ) . - pubmed
Substance P in rectal mucosa of children with chronic constipation . - pubmed
Substance P content was determined by radioimmunoassay in rectal mucosa of 17 children with idiopathic constipation and 9 with normal bowel movements who were used as controls . - pubmed
Substance P levels in rectal mucosa of children with soiling ( 11/17 ) did not differ from those of chronically constipated children without soiling ( 46.0 + /- 16 vs. 50.5 + /- 19 pg / mg net weight ) . - pubmed
In children with constipation , substance P levels did not correlate either with age or duration of symptoms . - pubmed
RESULTS : Most of the patients were in terminal phase ( 19 ) , the fundamental cause ( 17 cases ) that justified the use of the subcutaneous tract was the difficulty to take drugs by oral tract in the last days of life , attention on death throes . - pubmed
The drugs and initial average dose most used were : morphine 19 patients dose 100 mg/24 h , hyoscine butylbromide ( Buscapina ) , 13 patients , 60 mg/24 h , haloperidol 12 patients , 4 mg/24 h. The patients death was the main cause that justified the retirement of the continuous infusion ( 17 people sick ) , happening in its own home . - pubmed
Apoptosis in young rats with adriamycin - induced cardiomyopathy -- comparison with pirarubicin , a new anthracycline derivative . - pubmed
To investigate whether pirarubicin has a lower chronic cardiotoxicity compared with ADR , ADR or pirarubicin were injected weekly for 8 wk into young Wister rats via the tail vein . - pubmed
METHODS : 50 eyes of 50 consecutive patients with graft infection after an optical penetrating keratoplasty were included as cases ; 50 eyes of 50 patients with no graft infection were included as controls . - pubmed
Adeno - associated virus ( AAV ) is a member of the parvovirus family , is a nonpathogenic virus with a broad host cell range , and does not provoke a significant immune response upon infection . - pubmed
We review here recent advances in AAV vectors used for gene transfer of the haemophilias . - pubmed
A case of acquired haemophilia in a patient with lupus is reported . - pubmed
CASE REPORT : A 30 year - old woman with systemic lupus erythematosus developed a right coxalgia and ecchymotic skin lesions which were prominent on the right arm and forearm . - pubmed
We present and discuss the case of a patient with primitive cerebral localization of Wegener ' s Granulomatosis in which the diagnosis and the beginning of correct therapy were delayed , in spite of a rising c - ANCA titer , due to a misinterpretation of a bioptic specimen . - pubmed
UNLABELLED : The variation of capillary filtration rate ( CFR ) and ankle edema ( AE ) were evaluated in three groups of patients with venous hypertension with ambulatory venous pressure & gt ; 42 mmHg and in healthy subjects before and after treatment for four weeks with HR ( Paroven , Venoruton ; 0 -( beta - hydroxyethyl )- rutosides ) , a venoactive drug acting on the microcirculation and on capillary permeability . - pubmed
The decrease in the score in the groups of patients was correlated with the variation in edema and CFR . - pubmed
A new epothilone , 10,11 - didehydroepothilone D ( 5 ) , was isolated from a strain of the heterologous host Myxococcus xanthus genetically engineered to produce epothilone D ( 4 ) . - pubmed
High levels of HIV-1 replication occur following perinatal infection and antiretroviral drugs may not fully suppress viral load during the early years of childhood . - pubmed
Randomized phase III trial of single versus fractionated thoracic radiation in the palliation of patients with lung cancer ( NCIC CTG SC.15 ) . - pubmed
The European Organization for Research and Treatment of Cancer QLQ - C30 scores showed that patients receiving five fractions had a greater improvement in scores with respect to pain ( p = 0.04 ) . - pubmed
To investigate the ischaemia / reperfusion phenomenon in skin flaps , we first investigated the vascular anatomy of murine dorsal skin and then designed a suitable murine dorsal skin flap model . - pubmed
Inhibition of cusp and aortic wall calcification in ethanol- and aluminum - treated bioprosthetic heart valves in sheep : background , mechanisms , and synergism . - pubmed
Stentless bioprostheses fabricated from GA - fixed porcine aortic valves pose an important challenge in this regard , as pathologic calcification can affect not only the bioprosthetic cusps , but also the aortic wall segment . - pubmed
More specifically , we wanted to see whether or not there was any regular relationship between the differential time trends of the above 3 human neoplasias and their oncogene - tumor suppressor gene balances . - pubmed
The integrity of the above findings is discussed in the light of a number of pioneering achievements along the line of the steroid criminal theory of carcinogenesis in humans and in non - human mammals . - pubmed
[ Study on the effect of isonicotinic acid hydrazide and p - aminosalicylic acid on experimental tuberculosis in guinea pigs ] . - pubmed
[ Considerations on the discrepancies between in vitro sensitivity and clinical results in antibiotic therapy of infections caused by Staphylococcus pyogenes aureus ] . - pubmed
[ Blood circulation and oxygen consumption by the liver in experimental cirrhosis in dogs ] . - pubmed
Our results have potential application to the assessment of tumor characteristics in vivo in human tumors for individualized cancer therapy . - pubmed
We describe a 59 - year - old man with nephrotic syndrome that was diagnosed as suspected minimal change nephrotic syndrome by the routine examination of renal tissues at first biopsy , because renal histology showed segmental mild mesangial expansion with argyrophilic staining and partial foot process fusion without any deposition . - pubmed
Three - dimensional computerized analysis of diadochokinetic movements of Parkinsonian patients . - pubmed
The purpose of this study was to investigate the usability of a computerized movement analysis system in Parkinson ' s disease patients . - pubmed
MATERIAL AND METHODS : We analysed the effect of L - dopa in a group of 14 patients with idiopathic Parkinson ' s disease and compared the results to those of 14 control persons . - pubmed
A 74 - year - old woman presented with progressive mental deterioration following a low - grade fever and headache . - pubmed
We experienced a male patient with psoriasis and hypertension whose conditions were treated with tacalcitol ointment and thiazide , respectively , resulting in hypercalciuria and hypercalcemia . - pubmed
Thymoma was present in one of the ten patients . - pubmed
Compared with a similar historical group of patients with MG who underwent transsternal thymectomy , the VATS group was associated with significantly less analgesic requirement and shortened hospital stay . - pubmed
Effect of artificially induced hyperthermia on the electrocardiogram of the dog . - pubmed
Prognostic value of intratumoral vessel density in cutaneous mast cell tumors of the dog . - pubmed
The biological behaviour of canine cutaneous mast cell tumours ( MCTs ) is highly variable . - pubmed
The aim of this study was to investigate whether intratumoral microvessel density ( IMVD ) , as an indicator of angiogenesis , was predictive of biological behaviour in MCTs of canine skin , and to relate this parameter to histological grade and other histomorphological features . - pubmed
The relation of angiogenesis to biological behaviour and histological parameters of malignancy of cutaneous MCTs was consistent with previous findings in human and animal tumours . - pubmed
Human rights group accuses Russian government of hampering efforts to tackle HIV / AIDS . - pubmed
Dissatisfied with the treatment available , the authors report on the use of a closed , controlled drainage procedure in eight patients with severe edema of the lower limbs . - pubmed
In addition , the pain experienced by the patients has been monitored during treatment . - pubmed
Photobleaching was monitored by fluorescence imaging , and pain experienced by the patients was registered by using a visual analogue scale graded from 0 ( no pain ) to 10 ( unbearable pain ) . - pubmed
No significant difference in pain experienced by the patients during PDT was observed in varying the fluence rate from 30 to 75 mW cm(-2 ) . - pubmed
RESULTS : Here we report the construction and characterization of a highly redundant bacterial artificial chromosome ( BAC ) library constructed from a Norwegian aquaculture strain male of Atlantic salmon ( Salmo salar ) . - pubmed
METHODS : Ninety - one patients ( 37 tuberculous pleural effusions , 42 malignant pleural effusions of lung cancer and 12 transudates ) were included . - pubmed
Effects of raloxifene and low - dose simvastatin coadministration on plasma lipids in postmenopausal women with primary hypercholesterolemia . - pubmed
Despite the disappointments of recent large scale clinical trials evaluating the efficacy of antioxidants in cardiovascular disease , many therapeutic agents which have been used successfully in diabetic subjects at high risk for cardiovascular disease have a mechanism of action which includes an antioxidant capacity . - pubmed
A major advantage of this strategy is that it allows one standard cell line to be applied to all patients and this approach can be extended to the treatment of other tumour types . - pubmed
Encapsulated cells were angiographically placed into the tumour vasculature of 14 patients and followed by systemic low dose ifosfamide treatment . - pubmed
Four of the treated patients showed tumour regressions after capsule delivery and ifosfamide treatment in computer - tomography scans . - pubmed
The other 10 patients showed no further tumour growth ( i.e. - pubmed
Axillary recurrence in women with a negative sentinel lymph node and no axillary dissection in breast cancer . - pubmed
The purpose of this study was to determine the frequency of axillary lymph node recurrence in patients who had a negative sentinel lymph node and did not undergo axillary node dissection . - pubmed
For each woman with recurrence , the dates of recurrence , the site(s ) of recurrence , and the treatment for recurrence were recorded . - pubmed
Only two patients ( 0.6 % ) had an axillary recurrence . - pubmed
Cytotoxicity and transcriptional activation of stress genes in human liver carcinoma ( HepG2 ) cells exposed to iprodione . - pubmed
Experimental studies with mice have indicated that exposure to iprodione at dose levels 5 to 15 folds greater than the LOAEL for liver injury , induces microsomal enzyme activities , hepatocyte proliferation , hepatomegaly , centrilobular hypertrophy , diffuse hypertrophy , and an increase in lauric acid hydroxylation . - pubmed
Viral hepatitis B ( HBV ) and C ( HCV ) are a significant cause of morbidity and mortality in patients coinfected with human immunodeficiency virus ( HIV ) . - pubmed
In HBV / HIV coinfection , there is a higher frequency of HBV replication , and higher rates of HBV - associated liver disease . - pubmed
HIV / HBV coinfection is associated with an increased frequency of hepatotoxicity in patients receiving highly active antiretroviral therapy ( HAART ) , and reactivation of clinical hepatitis is observed upon stopping HBV - active anti - HIV drugs . - pubmed
In older humans , infusions of endothelial agonists suggest endothelial dysfunction , due in part to less nitric oxide ( NO)- and prostaglandin ( PG)-mediated vasodilatation , and a shift toward PG - mediated vasoconstriction . - pubmed
Notably , in young adults , inhibition of NO and PGs during exercise decreases exercise hyperaemia by approximately 20 and approximately 12 % , respectively . - pubmed
We tested our first hypothesis that in older humans inhibition of NO would decrease hyperaemia , but that inhibition of PGs would increase hyperaemia by blocking vasoconstrictor PGs . - pubmed
L - NAME reduced steady - state exercise hyperaemia by 12 + /- 3 % in older subjects ( P<0.01 ) , whereas ketorolac had no net effect on blood flow ( 3 + /- 6 % , P>0.4 ) . - pubmed
By comparing these results with our previous results in young adults , we tested our second hypothesis that in older humans inhibition of NO or PGs would have less impact on exercise hyperaemia due to less vasodilatation from these signals . - pubmed
Our results suggest that , compared with young adults , in older humans the relative contribution of NO to exercise hyperaemia is reduced approximately 45 % ( 22 + /- 4 versus 12 + /- 3 % ) , but the role of PG in mediating vasodilatation is lost in ageing human skeletal muscle . - pubmed
Lower exercise hyperaemia in older humans may be mediated in part by less NO- and PG - mediated vasodilatation during exercise . - pubmed
Here , we report a patient with RDD who presented a dramatic and sustained response with cladribine . - pubmed
Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients . - pubmed
The risk of death in hemodialysis patients treated with calcium - containing phosphate binders or sevelamer is not known . - pubmed
The greater risk of death for patients treated with calcium - containing phosphate binders persisted after full multivariable adjustment ( P=0.016 , hazard ratio 3.1 , CI 1.23 - 7.61 ) . - pubmed
INTRODUCTION : We report two cases of patients with prostate cancer who underwent haematological complications from the disease . - pubmed
CLINICAL CASES : Diffuse intravascular coagulopathy ( with thrombopenia ) was observed in two patients ( 55 and 59 years - old ) diagnosed with prostate cancer . - pubmed
In one patient who had normal prostate at clinical examination , thrombopenia with incomplete diffuse intravascular coagulopathy and biological inflammatory led to diagnosis . - pubmed
In the other patient diffuse intravascular coagulopathy followed introduction of hormonal therapy and lead to the patient 's death . - pubmed
DISCUSSION : Patients with metastatic hormone - refractory prostate carcinoma may have life - threatening coagulation complications due to their disease . - pubmed
When attacked by HIV , the immune system counteracts infection with elicitation of HIV - specific antibodies and cytotoxic T lymphocytes . - pubmed
The role of PCI in the management of acute coronary syndromes is already well defined , and has increased the preference for an invasive rather than a conservative approach in high - risk patients without ST elevation and the preference for primary angioplasty rather than thrombolysis in those with ST elevation . - pubmed
The development and implementation of integrated coronary syndrome treatment networks will enable human and material resources to be used efficiently , and will guarantee rapid access to high - quality PCI for those who need it . - pubmed
At present , there is extensive research into noncoronary interventions , which , in the not too distant future , could provide percutaneous treatment for the many elderly patients with severe aortic stenosis who are not currently eligible for surgery . - pubmed
Topiramate in patients with episodic migraine : reducing the risk for chronic forms of headache . - pubmed
OBJECTIVE : The aim was to evaluate whether preventive treatment with topiramate in patients with episodic migraine reduces the risk of developing chronic forms of headache . - pubmed
METHODS : Pooled data from 3 trials in patients with episodic migraine randomized either to treatment with 100 mg topiramate per day ( n = 384 ) or with placebo ( n = 372 ) were analyzed with regard to the number of headache days during a prospective 4 - week baseline period and the individual final 4 weeks of each patient 's treatment during the planned 26 - week double - blind treatment period . - pubmed
At the end of the study , 8 versus 16 patients fulfilled International Headache Society criteria of chronic headache ( odds ratio : 2.11 , P= .082 ) . - pubmed
Moreover , a significantly lower number of patients receiving topiramate treatment reported an increase in headache days per month by the end of the study when compared to placebo ( 66 vs 88 patients , respectively ; odds ratio : 1.49 , P & lt ; .05 ) . - pubmed
CONCLUSION : Preventive treatment with topiramate in patients with episodic migraine may reduce the risk of developing chronic forms of headache . - pubmed
Ascorbate uptake in normal and diabetic rat retina and retinal pigment epithelium . - pubmed
The RPE and retina of diabetic rats presented lower levels of AA accumulation . - pubmed
Two of the 10 patients died of liver failure 5 and 12 years after diagnosis , respectively . - pubmed
Accordingly , the purpose of this study was to determine if intense normobaric hypoxic exercise could induce pulmonary edema in women . - pubmed
BACKGROUND : Previous studies have shown that the incidence of atrial fibrillation after atrial flutter ablation is approximately 20 % among patients presenting with typical atrial flutter and no history of fibrillation . - pubmed
OBJECTIVE : The purpose of this study was to provide a more accurate perspective on the long - term risk of atrial fibrillation in patients presenting with isolated typical flutter . - pubmed
RESULTS : Postablation atrial fibrillation was identified in 40 ( 50 % ) of 80 patients , and an additional three patients presented with atypical atrial flutter , after a mean follow - up of 29.6 + /- 21.7 months . - pubmed
There was no difference in age , left atrial size , hypertension , structural heart disease , or left ventricular dysfunction in patients who developed atrial fibrillation compared with those who did not . - pubmed
CONCLUSION : Atrial fibrillation occurs in over half of patients who present with isolated typical flutter after cavotricuspid isthmus ablation . - pubmed
Asymptomatic patients should be screened for recurrent arrhythmias indefinitely after ablation . - pubmed
In certain patients , atrial fibrillation and flutter may be different expressions of the same electrical disease , and eradication of the flutter circuit will not prevent the eventual manifestation of atrial fibrillation . - pubmed
Drospirenone / ethinylestradiol 3mg/20microg ( 24/4 ) is approved in the US for the prevention of pregnancy in women , for the treatment of the symptoms of premenstrual dysphoric disorder ( PMDD ) and for the treatment of moderate acne vulgaris in women who wish to use an oral contraceptive for contraception . - pubmed
The backscroll illusion refers to the apparent motion perceived in the background of a movie image that presents a locomotive object such as a person , an animal , or a vehicle . - pubmed
Our hypothesis has implications for the use of drugs or devices in the treatment of patients with stress cardiomyopathy . - pubmed
The effect of oral therapy with cobaltous chloride on the blood of patients suffering with chronic suppurative infection . - pubmed
These results indicate that reactive astrogliosis and delayed neuronal death , at least in rat hippocampus , are sequential pathological events following MCAO . - pubmed
Main outcome measure was basal cervical dilatation while the secondary outcome measures were operative blood loss , time duration of surgery , patient satisfaction , pain perception and adverse effects . - pubmed
One patient had lateral ankle instability at 5 weeks and therefore the therapy continued with prolonged immobilization and then rehabilitation at a slower pace . - pubmed
We describe here the case of a 39 - year - old woman with a cortisol - producing adrenal adenoma and she presented with endometrial hyperplasia and hypertension without the specific characteristics of Cushing ' s syndrome . - pubmed
METHODS : Immunohistochemistry was performed on cryosections obtained from five pairs of normal and five pairs of age - matched diabetic human retinas . - pubmed
The evaluation of markers of prostatic inflammation and function of the prostate gland in patients with chronic prostatitis . - pubmed
MATERIALS AND METHODS : The study involved 46 patients with chronic prostatitis . - pubmed
trachomatis prostate infection was detected in 17.4 % of the patients and all of these men had higher inflammation parameters and lower citric acid concentrations . - pubmed
Extracapsular extension was reported in 13.5 % to 26 % of patients , and seminal vesicle invasion was reported in 2.9 % to 8.2 % of patients . - pubmed
javanica infection , M. - pubmed
Even though the majority of patients had glioblastoma , only 5/67 had received adjuvant therapy . - pubmed
Comparative survival in patients with postresection recurrent versus newly diagnosed non - small - cell lung cancer treated with radiotherapy . - pubmed
PURPOSE : To compare the survival of postresection recurrent vs. newly diagnosed non - small - cell lung cancer ( NSCLC ) patients treated with radiotherapy or chemoradiotherapy . - pubmed
METHODS AND MATERIALS : The study population consisted of 661 consecutive patients with NSCLC registered in the radiation oncology databases at two medical centers in the United States between 1992 and 2004 . - pubmed
Of the 661 patients , 54 had postresection recurrent NSCLC and 607 had newly diagnosed NSCLC . - pubmed
CONCLUSION : Our institutional data have shown that patients with postresection recurrent NSCLC achieved survival comparable to that of newly diagnosed NSCLC patients when they were both treated with radiotherapy or chemoradiotherapy . - pubmed
These findings suggest that patients with postresection recurrent NSCLC should be treated as aggressively as those with newly diagnosed disease . - pubmed
Various strains of Atlantic salmon exhibit different levels of susceptibility to infections with the ectoparasitic monogenean Gyrodactylus salaris . - pubmed
OBJECTIVE : This article aims to describe an approach to diagnosis and management based on the location of the pain , the patient 's age , and the type of activity being undertaken . - pubmed
STUDY DESIGN : A multiple - comparative study between normal and low back pain ( LBP ) patients before and after rehabilitation . - pubmed
OBJECTIVE : To examine whether there is a change in flexion - relaxation phenomenon in sitting in LBP patient following a rehabilitation treatment . - pubmed
Previous study has reported an absence of flexion - relaxation phenomenon in LBP patients during sitting . - pubmed
However , it is unknown whether there is a difference in flexion - relaxation phenomenon in sitting in LBP patients before and after rehabilitation treatment . - pubmed
METHODS : A total of 20 normal subjects and 25 chronic LBP patients who underwent a 12 weeks rehabilitation program were recruited . - pubmed
Surface electromyography recordings during upright sitting and flexed sitting were taken from the paraspinal muscles ( L3 ) bilaterally from the normal subjects , and in the LBP patients before and after the rehabilitation treatment . - pubmed
Flexion - relaxation phenomenon in sitting , expressed as a ratio between the average surface electromyography activity during upright and flexed sitting , was compared between normal and patients ; and in LBP patients before and after rehabilitation . - pubmed
RESULTS : Flexion - relaxation ratio in sitting in normal subjects ( Left : 6.83 + /- 3.79 ; Right : 3.45 + /- 2.2 ) presented a significantly higher ( Left : P & lt ; 0.001 ; Right : P & lt ; 0.05 ) value than LBP patients ( Left : 3.04 + /- 2.36 ; Right : 2.02 + /- 1.49 ) . - pubmed
An increase in flexion - relaxation ratio in sitting was observed in LBP patients after rehabilitation ( Left : 4.69 + /- 3.94 , P & lt ; 0.05 ; Right : 3.58 + /- 2.97 , P & lt ; 0.001 ) , together with a significant improvement ( P & lt ; 0.05 ) in subjective tolerance in sitting and standing , abdominal and back muscle endurance , lifting capacity , and range of motion . - pubmed
CONCLUSION : Flexion - relaxation ratio in sitting has demonstrated its ability to discriminate LBP patients from normal subjects , and to identify changes in pattern of muscular activity during postural control after rehabilitation . - pubmed
METHODS : Consecutive series of patients with primary subfoveal CNV secondary to pathological myopia treated with intravitreal ranibizumab 0.5 mg ( 0.05ml ) were included prospectively in this study . - pubmed
Hepatitis E virus ( HEV ) has at least 2 distinct epidemiological profiles : ( 1 ) large outbreaks and epidemics in developing countries , usually caused by HEV genotype 1 , resulting in high morbidity and mortality among pregnant women and young children , and ( 2 ) very few symptomatic cases of HEV genotype 3 , most cases without symptoms or clear source(s ) of infection , but frequent seroreactivity in 5%-21 % of asymptomatic persons in developed countries . - pubmed
CONCLUSIONS : Sacral neuromodulation with the tined lead procedure is a safe and effective treatment for patients with overactive bladder symptoms or urinary retention . - pubmed
[ Construction of the genetically attenuated bacteria Bordetella pertussis devoid of dermonecrotic toxin activity and producing modified nontoxic pertussis toxin form ] . - pubmed
BACKGROUND : Infection with Helicobacter pylori triggers a chronic gastric inflammation that can progress to atrophy and gastric adenocarcinoma . - pubmed
METHODOLOGY / PRINCIPAL FINDINGS : By using a mouse model of infection and gastric biopsies from 29 individuals , we have analyzed macrophage recruitment and polarization during H. pylori infection by flow cytometry and real - time PCR . - pubmed
Multiple pathogenic mechanisms by which HIV and antiretroviral agents lead to dyslipidemia have been hypothesized , but they are still controversial . - pubmed
Hutchinson - Gilford progeria syndrome ( HGPS ) is a rare and fatal human premature ageing disease , characterized by premature arteriosclerosis and degeneration of vascular smooth muscle cells ( SMCs ) . - pubmed
Here we report the generation of induced pluripotent stem cells ( iPSCs ) from fibroblasts obtained from patients with HGPS . - pubmed
PURPOSE : To evaluate the ocular hypotensive efficacy of 0.05 % , 0.1 % and 0.25 % AR-12286 Ophthalmic Solutions in patients diagnosed with ocular hypertension or glaucoma . - pubmed
METHODS : Subjects ( n = 89 ) with elevated intraocular pressure ( IOP ) were assigned randomly to receive either 1 of 3 concentrations of AR-12286 or its vehicle . - pubmed
After once - daily evening dosing , hyperemia was seen in less than 10 % of patients . - pubmed
CONCLUSIONS : AR-12286 was well tolerated and provided clinically and statistically significant ocular hypotensive efficacy in patients with ocular hypertension and glaucoma . - pubmed
Validation of doripenem dosing in patients with end - stage renal disease receiving hemodialysis . - pubmed
Systematic studies and clinical trials are difficult to perform in patients with cognitive impairment ; recommendations for evaluating and treating delirium are based primarily upon clinical observation and expert opinion . - pubmed
The patient developed encephalopathy and liver failure and died despite prompt initiation of dexamethasone therapy . - pubmed
The current prognosis of multiple myeloma patients with liver failure due to LCDD is dismal . - pubmed
In two well designed phase III trials , 14 days ' treatment with bilastine was associated with a significantly lower area under the effect curve ( AUEC ) for the reflective total symptom score ( TSS ) than placebo in patients with symptomatic seasonal allergic rhinitis . - pubmed
Additionally , reflective nasal symptom scores were significantly lower in bilastine than placebo recipients in patients with a history of seasonal allergic rhinitis who were challenged with grass pollen allergen in a single - centre , phase II study . - pubmed
In another well designed phase III trial , compared with placebo , bilastine was associated with a significantly greater change from baseline to day 28 in the mean reflective daily urticaria symptom score in patients with chronic urticaria . - pubmed
METHODS : This retrospective paper included 216 patients with HT , issued from an iodine - replete area . - pubmed
RESULTS : The morphologic investigation revealed 9 patients with DTC and 12 cases with benign thyroid disease ( BTD).None of the US analyzed characteristics provided sufficient accuracy for the diagnosis of DTC in cases with HT . - pubmed
This review summarizes the epidemiology , associated etiology , diagnosis , management , and outcome of patients with SCAD . - pubmed
CONCLUSIONS : This study confirmed that varicella vaccine is effective at preventing chicken pox , with no waning noted over a 14 - year period . - pubmed
The effect of precipitation on the transmission of Japanese encephalitis ( JE ) virus in nature : a complex effect on antibody - positive rate to JE virus in sentinel pigs . - pubmed
BACKGROUND : Adaptation of Pseudomonas aeruginosa to different living conditions is accompanied by microevolution resulting in genomic diversity between strains of the same clonal lineage . - pubmed
CONCLUSIONS : The higher geographical and temporal distance of the clone CHA isolates was associated with an increased intraclonal genome diversity compared to the more closely related clone TB isolates derived from a common source demonstrating the impact of habitat adaptation on the microevolution of P. - pubmed
We describe an expansile necrotising pneumonia caused by Norcardia in a HIV - infected 3 - week - old baby . - pubmed
SHU atypical ( aHUS ) , that is , not associated with Escherichia coli Shiga toxinproducing , is seen in 5 to 10 % of cases of Hemolytic Uremic Syndrome ( HUS ) , and can occur at any age and may be sporadic or familial . - pubmed
Dysregulated phosphatidylinositol signaling promotes endoplasmic - reticulum - stress - mediated intestinal mucosal injury and inflammation in zebrafish . - pubmed
INTRODUCTION : Postoperative sore throat is a common complaint in patients with endotracheal intubation and has potentially dangerous complications . - pubmed
We determined whether use of a mandatory checklist of perioperative practices believed to reduce the risk of prosthesis infection would impact patient safety . - pubmed
Although the specific factors that led to the infection outbreak and subsequent cessation of infections are unknown , we have shown that use of a checklist was associated with a dramatic impact on patient safety . - pubmed
This is determined by the exposure of patients in shock with acutely damaged end - organs and high catecholamine support to a significant surgical trauma . - pubmed
OBJECTIVE : To evaluate the efficacy and tolerability of a multimodal skin - brightening regimen in subjects with facial hyperpigmentation . - pubmed
RESULTS : At baseline and Weeks 4 , 8 , and 12 , subjects were assessed for overall hyperpigmentation and global improvement . - pubmed
Vaccination against oncogenic human papillomavirus infection in HIV - infected populations : review of current status and future perspectives . - pubmed
UNLABELLED : Background Men and women with HIV infection are at increased risk of developing cancers associated with human papillomavirus ( HPV ) . - pubmed
The two licensed prophylactic HPV vaccines protect against de novo infection with HPV-16 and HPV-18 , which cause the majority of HPV - associated cancers . - pubmed
To specifically recommend prophylactic HPV vaccination in people with HIV , the vaccines must be safe and immunogenic in immunosuppressed people at a high risk of HPV infection . - pubmed
This review aims to summarise the current knowledge from published HPV vaccine trials in HIV - infected populations , to compile scheduled and ongoing HPV vaccine trials with HIV - positive study populations and to extrapolate the relevant knowledge about HPV vaccine efficacy in HIV - negative populations to an HIV context . - pubmed
CONCLUSION : Prophylactic HPV vaccination appears safe , immunogenic and , by extrapolation , likely to reduce HPV - associated cancer development among persons with HIV infection . - pubmed
The combined chemoimmunotherapy was applied in the treatment of mice with subcutaneously ( SC ) growing , advanced MC38 colon carcinoma . - pubmed
CONCLUSION : Iron - based phosphate binders are as effective as sevelamer and well tolerated for hyperphosphatemia in dialysis patients . - pubmed
Iron - based phosphate binders appear to have a beneficial effect on renal anemia in patients receiving dialysis . - pubmed
Information was obtained for each patient treated , including pulp and peri - radicular diagnosis for the tooth , presence of pre - operatory pain , type of medication being used , type of instrumentation technique used and number of appointments needed to complete the root canal treatment . - pubmed
CONCLUSIONS : Flare - ups were found to be affected significantly by gender of patient , presence of radiolucent lesions , patients taking pre - operative analgesic or anti - inflammatory drugs and on type of instrumentation technique . - pubmed
METHODS : We measured EIM in 8 arm and leg muscles in 61 boys with Duchenne muscular dystrophy ( DMD ) and 31 healthy boys , ages 3 - 12 years , at 5 centers . - pubmed
DESIGN : Body mass index , triceps skinfolds , and waist , arm , and leg circumferences were collected on 29 adolescents aged 14 - 17 yrs with spinal cord injury , cerebral palsy , or spina bifida . - pubmed
Non - stenotic intracranial arteries have atherosclerotic changes in acute ischemic stroke patients : a 3 T MRI study . - pubmed
METHODS : Thirty - three patients with acute ischemic stroke and 36 control patients were analyzed . - pubmed
Acute ischemic stroke patients were divided according to TOAST classification . - pubmed
AreaInner did not significantly differ between stroke patients and controls ( P = 0.619 ) . - pubmed
However , AreaOuter , AreaVW , and RI were significantly larger in stroke patients ( P & lt ; 0.001 ) . - pubmed
CONCLUSION : In patients with acute ischemic stroke , wall thickening and positive remodeling are evident in non - stenotic intracranial arteries . - pubmed
CASE : A 30 - year - old patient with a previous cesarean delivery was undergoing surgical termination of pregnancy at 13 weeks ' gestation for a lethal fetal malformation . - pubmed
Acute oral complications in a pediatric patient with acute lymphoid leukemia . - pubmed
Pseudomonas aeruginosa is a low - virulence pathogen that can cause infection in immunocompromised patients . - pubmed
aeruginosa as the bacteria responsible for intraoral inflammation , and antibiotic therapy targeting P. - pubmed
Here , we report a case involving a 10 - year - old patient with acute lymphoid leukemia ( ALL ) , in which P. - pubmed
Comparison of the Hyaluronic Acid Vaginal Cream and Conjugated Estrogen Used in Treatment of Vaginal Atrophy of Menopause Women : A Randomized Controlled Clinical Trial . - pubmed
BACKGROUND : Vaginal atrophy is a common complication in menopause which does not improve with time and , if untreated , can affect the quality of life for women . - pubmed
METHODS : This study was a randomized controlled clinical trial on 56 menopausal women with symptoms of vaginal atrophy ; they were randomly allocated to two groups ( recipient conjugated estrogen and hyaluronic acid ) . - pubmed
METHODS : A retrospective review of all surgical patients with non - small cell lung cancer at a single institution imaged between 2000 and 2006 with ( 18 ) F - fluorodeoxyglucose positron emission tomography before or after induction therapy was performed . - pubmed
[ Ecological executive function characteristics and effects of executive function on social adaptive function in school - aged children with epilepsy ] . - pubmed
OBJECTIVE : To explore the characteristics of ecological executive function in school - aged children with idiopathic or probably symptomatic epilepsy and examine the effects of executive function on social adaptive function . - pubmed
METHODS : A total of 51 school - aged children with idiopathic or probably symptomatic epilepsy aged 5 - 12 years at our hospital and 37 normal ones of the same gender , age and educational level were included . - pubmed
RESULTS : The scores of school - aged children with idiopathic or probably symptomatic epilepsy in global executive composite ( GEC ) , behavioral regulation index ( BRI ) and metacognition index ( MI ) of BRIEF ( ( 62 + -12 ) , ( 58 + -13 ) and ( 63 + -12 ) , respectively ) were significantly higher than those of the control group ( ( 47 + -7 ) , ( 44 + -6 ) and ( 48 + -8 ) , respectively))(P<0.01 ) . - pubmed
The scores of school - aged children with idiopathic or probably symptomatic epilepsy in adaptive behavior quotient ( ADQ ) , independence , cognition , self - control ( ( 86 + -22 ) , ( 32 + -17 ) , ( 49 + -14 ) , ( 41 + -16 ) , respectively ) were significantly lower than those of the control group ( ( 120 + -12 ) , ( 59 + -14 ) , ( 59 + -7 ) and ( 68 + -10 ) , respectively))(P<0.01 ) . - pubmed
CONCLUSIONS : School - aged children with idiopathic or probably symptomatic epilepsy may have significantly ecological executive function impairment and social adaptive function reduction . - pubmed
RESULTS : A total of nine studies were included in the analysis , including 384 patients with 390 aneurysms . - pubmed
Moreover , the search for competitive alternatives to using colistin with swine is of paramount importance to preserve the effectiveness of this antibiotic for the treatment of MDR - GNB infections in human medicine . - pubmed
For this purpose we exposed male zebrafish to two types of social interactions : ( 1 ) real opponent interactions , from which a Winner and a Loser emerged ; and ( 2 ) mirror - elicited interactions , that produced individuals that did not experience a change in social status despite expressing similar levels of aggressive behavior to those of participants in real - opponent fights . - pubmed
OBJECTIVE : This study aimed to assess the presence of pancreatic hyperenzymemia in patients with pancreatic cystic lesions as compared to other chronic diseases of the pancreas . - pubmed
METHODS : Ninety - one patients were studied : 32 had mucinous cystic lesions , 35 had chronic pancreatitis ( CP ) , and 24 had pancreatic ductal adenocarcinoma ( PDAC ) . - pubmed
Surgery was carried out in 10 of the 32 patients with mucinous cystic lesion ( 7 of them had severe dysplasia ) , in 5 patients with CP , and in 9 patients with PDAC . - pubmed
BACKGROUND AND OBJECTIVE : Patients with small ( & lt;5 mm ) unruptured intracranial aneurysms ( UIAs ) are at risk of subarachnoid hemorrhage , but risk assessment of these patients remains controversial in daily clinical practice . - pubmed
We aimed to identify the risk factors of aneurysmal rupture in these patients . - pubmed
METHODS : We retrospectively analyzed consecutive patients with small UIAs who were admitted to our center between February 2009 and December 2014 . - pubmed
RESULTS : A total of 548 patients with 618 small intracranial aneurysms ( 267 ruptured and 351 unruptured ) were included . - pubmed
Factors associated with acute - phase response of bisphosphonate - naive or pretreated women with osteoporosis receiving an intravenous first dose of zoledronate or ibandronate . - pubmed
Univariate and multivariate analyses suggested that miR-103 overexpression was a poor independent prognostic factor for triple - negative breast cancer patients . - pubmed
Comparative analysis of HPV16 gene expression profiles in cervical and in oropharyngeal squamous cell carcinoma . - pubmed
Human papillomavirus type 16 ( HPV16 ) is the major cause of cervical cancer and of a fraction of oropharyngeal carcinoma . - pubmed
Bioinformatics Analysis on Molecular Mechanism of Green Tea Compound Epigallocatechin-3 - Gallate Against Ovarian Cancer . - pubmed
Intensive preoperative rehabilitation improves functional capacity and postoperative hospital length of stay in elderly patients with lung cancer [ synopsis ] . - pubmed
Giant RPLS commonly occurs in adults aged 40 - 60 y and presents atypical clinical manifestations . - pubmed
A Case of Ophitoxaemia - Snake Poisoning : Snake Identified , Echis Carinata , by the Natural History Society , Bombay . - pubmed
INTRODUCTION : Treatment for anal fistulas in patients with Crohn ' s disease is still challenging , even for the expert surgeon . - pubmed
METHODS : A systematic review of the literature , selecting series of patients affected by Crohn ' s disease and anal fistulas and treated using advancement flap technique was performed . - pubmed
CONCLUSION : The review concludes that the advancement flap technique to treat anal fistulas in patients with Crohn ' s disease is an adequate alternative . - pubmed
Notably , 3 - S - fire - exposed mice were the only group to develop acute lung injury , possibly because they inhaled the highest concentrations of hazardous air toxicants ( e.g. - pubmed
Hepatoprotective effects of garlic against ethanol - induced liver injury : A mini - review . - pubmed
Along with the prosperity in the use of herbal medicines for the treatment of human diseases in recent decades , a series of studies have focused on the beneficial effects of garlic against ALD . - pubmed
This mini - review highlighted the protective roles of garlic against ALD and the potential mechanisms . - pubmed
Results : The most potent antitussive effect was observed for Nigella sativa and Linum usitatissimum on coughs induced by sulfur dioxide . - pubmed
Artemisia absinthium showed a higher antitussive effect on cough induced by ammonia compared with the other studied medicinal plants . - pubmed
The antitussive effects of Cuminum cyminum and Glycyrrhiza glabra were more potent on cough induced by citric acid than other medicinal plants . - pubmed
Spotlight on eltrombopag in the treatment of children with chronic immune thrombocytopenia . - pubmed
The intensive care service ( ICS ) saves lives and rescues the neurological function of stroke patients . - pubmed
We wondered the different utilization of ICS for patients with ischemic and hemorrhagic stroke , especially those who died within 30 days after stroke . - pubmed
Sixty - seven patients died during 2011 to 2015 due to acute stroke ( 42 due to intracranial hemorrhage [ ICH ] ; 25 due to cerebral infarct [ CI ] ) . - pubmed
Diverse human tumors obtained directly from surgery or biopsy can grow at high frequency in 3 - dimensional Gelfoam histoculture for long periods of time and still maintain many of their in vivo properties . - pubmed
This is the first report on the efficacy of colchicine in a patient with AOSD which was refractory to immunosuppressive treatments including biologics . - pubmed
CASE PRESENTATION : A 24 - years Japanese female patient was referred to our hospital for the flare - up of AOSD under the combined treatments with steroid , immunosuppressants , and biologics . - pubmed
Glioblastoma multiforme ( GBM ) is the most lethal glioma variant in the adult brain and among the deadliest of human cancers . - pubmed
The nucleotide sequences of 24 BQCV isolates showed the highest identity ( 86.4 % ) with strains from Europe at the polyprotein gene , whilst the Serbian isolates between each other showed 98.5 % similarity . - pubmed
Evaluating the suitability of honey for the detection of the viral disease by simultaneous testing of live , dead bees , and honey from the same hive , it was shown that the honey can be successfully used for the detection of BQCV . - pubmed
OBJECTIVES : The primary objective of this observational study was to determine whether caffeine consumed habitually as part of a daily diet was associated with experimental pain sensitivity using noxious stimuli in a non - clinical sample of 62 community - dwelling adults between 19 and 77 years old . - pubmed
At the end of treatment , arterial BP was measured , and hyperinsulinemic - euglycemic clamps were performed in conscious obese mice receiving vehicle , captopril , captopril plus A779 , or A779 ( n = 6 - 13 / group ) . - pubmed
Safety and efficacy of mechanical thrombectomy with stent - retrievers in anticoagulated patients with anterior circulation stroke . - pubmed
RESULTS : The following statistically insignificant differences were found in 26 patients on OAC versus 259 patients without OAC : occurrence of symptomatic intracerebral haemorrhage 7.7 % versus 8.1 % , achievement of successful recanalisation 69.2 % versus 82.6 % , good 90 - day clinical outcome 34.6 % versus 56.8 % , 90 - day mortality 26.9 % versus 20.8 % ( p>0.05 in all cases ) . - pubmed
CONCLUSIONS : MT with stent - retrievers is safe and effective in ACS patients on OAC . - pubmed
[ Short - term Outcome of Uniportal and Three Portal Video - assisted Thoracic Surgery for Patients with Non - small Cell Lung Cancer ] . - pubmed
METHODS : We retrospectively evaluated 266 patients with NSCLC who underwent intended VATS lobectomy by a single surgical team in our ward between January 2016 and August 2017 . - pubmed
Human lens epithelial cell line SRA01 / 04 was subjected to H 2 O 2 to mimic a cell model of cataract . - pubmed
METHODS : Epithelial and stromal tissues from malignant and normal human prostate were obtained by laser capture microdissection . - pubmed
The PTXL could be effectively uptaken into human keloids fibroblast ( HKFs ) in a time - dependent manner . - pubmed
Meanwhile , in vivo studies indicated that the PTXL had better performance on inhibiting the keloids growth compared to the PTX in keloid - bearing BALB / c nude mice model . - pubmed
Prevalence of cognitive impairment in patients with substance use disorder . - pubmed
DESIGN AND METHODS : The Montreal Cognitive Assessment was administered to outpatients seeking treatment for substance use disorder . - pubmed
Patient characteristics ( age , years of regular use , polysubstance use , severity of dependence / abuse , depression , anxiety and stress ) were also taken into account . - pubmed
Aqueous leaf extract of Clinacanthus nutans improved metabolic indices and sorbitol - related complications in type II diabetic rats ( T2D ) . - pubmed
All rats except normal control rats were fed with a high - fat diet for 8 weeks to induce obesity and subsequently injected with 35 mg / kg streptozotocin to induce type II diabetes . - pubmed
Diabetic rats administered with C. - pubmed
Sorbitol levels in the kidney , lens , and nerve were reduced in diabetic rats administered with C. - pubmed
Although MALDI - TOF mass spectrometry recognized all Cronobacter sakazakii and Cronobacter malonaticus strains , it could not identify Cronobacter muytjensii strain . - pubmed
Although MALDI - TOF mass spectrometry recognized all Cronobacter sakazakii and Cronobacter malonaticus strains , it could not identify Cronobacter muytjensii strain . - pubmed
CASE REPORT : A 64 - year - old woman presented with a 2 - year history of repeated right waist pain and a 1 - month history of nausea , vomiting , and frequent and urgent urination . - pubmed
A CASE REPORT : The authors describe a case of a 72 - year - old female with primary AI ( Addison ' s disease ) after adrenalectomy due to adrenal hypertrophy she underwent in childhood . - pubmed
The authors suggest that each patient with adrenal crisis as well as with severe hyponatremia should be evaluated by echocardiography . - pubmed
Three patients suffered perioperative complications ( including colonic ischaemia , rectal perforation and arterial bleeding ) . - pubmed
Five patients ( 21.7 % ( 5/23 ) ) had an anastomotic leak treated with Ta drainage in two patients . - pubmed
The aim of this study was to compare the treatment outcomes of chemotherapy , surgery , and combination therapy in patients with lymph node - positive bladder cancer . - pubmed
From 1 January 2010 to 31 December 2015 , patients with bladder cancer presenting local lymph node metastasis at the time of diagnosis were treated with a single treatment strategy , with either radical cystectomy or chemotherapy or with a combined strategy using both . - pubmed
Out of 230 patients with bladder cancer , 44 ( 19.1 % ) were treated with palliative chemotherapy , 30 ( 13.0 % ) with neoadjuvant chemotherapy followed by cystectomy , 129 ( 56.1 % ) with cystectomy followed by adjuvant chemotherapy , and 27 ( 11.7 % ) with cystectomy alone . - pubmed
This study represents an advancement in understanding the impact of clinical treatment patterns of lymph node - positive bladder cancer through comparison of survival data of patients treated with different therapeutic strategies . - pubmed
Our findings support a favourable priming - induced acceleration of the VO2 kinetics response in middle - aged individuals with uncomplicated T2D attributed to an enhanced matching of microvascular O2 delivery to utilisation . - pubmed
It is worthy to note that only one patient presented preoperatively with bladder incontinence , urgency , and frequency . - pubmed
Almost immediately in the postoperative phase , the patient 's frequency and urgency improved , and the bladder function normalized within two weeks of having the tumor removed . - pubmed
Splenic ischemic preconditioning attenuates oxidative stress induced by hepatic ischemia - reperfusion in rats . - pubmed
PURPOSE : To evaluate the effects of splenic ischemic preconditioning ( sIPC ) on oxidative stress induced by hepatic ischemia - reperfusion in rats . - pubmed
Animals from IRI group were subjected to 45 minutes of partial liver ischemia ( 70 % ) . - pubmed
Eryngium carlinae Ethanol Extract Corrects Lipid Abnormalities in Wistar Rats with Experimental Diabetes . - pubmed
Eryngium carlinae is a plant used in traditional medicine to treat lipid abnormalities . - pubmed
Transcatheter Treatment of a Symptomatic Giant Iliac Artery Aneurysm with a BeGraft Peripheral Stent in a 2 - Year - Old Child . - pubmed
A 2 - year - old girl presented with severe abdominal pain due to a giant iliac artery aneurysm . - pubmed
This case involves a 5 year old boy with gross hematuria who was found to have an 8 cm pelvic mass , likely arising from the prostate and extending along the bladder wall . - pubmed
Aim : The aim of this study was to assess treatment modalities , treatment response , toxicity profile , disease progression and outcomes in 14 patients with a confirmed diagnosis of primary cutaneous T - cell lymphoma ( PCTCL ) treated with total skin electron beam therapy ( TSEBT ) . - pubmed
Materials and Methods : This is a retrospective study of patients with PCTCL , diagnosed and treated in a reference center in Mexico City , analyzing treatment modalities , response to treatment , long - term outcome , and mortality . - pubmed
Newcastle disease virus induces testicular damage and disrupts steroidogenesis in specific pathogen free roosters . - pubmed
Newcastle disease ( ND ) , which is caused by Newcastle disease virus ( NDV ) , can cause heavy economic losses to the poultry industry worldwide . - pubmed
If symptoms suggestive for COVID-19 are reported , family members , including children < 14 years , are offered a pharyngeal swab taken at the Division of Infectious Diseases and Tropical Medicine , LMU University Hospital Munich , for molecular testing for SARS - CoV-2 . - pubmed
The potential impact of human visceral leishmaniasis vaccines on population incidence . - pubmed
We implement four characteristics from different human VL vaccine candidates into two published VL transmission model variants to estimate the potential impact of these vaccine characteristics on population - wide anthroponotic VL incidence on the Indian subcontinent ( ISC ) . - pubmed
Defocus Curve and Patient Satisfaction with a New Extended Depth of Focus Toric Intraocular Lens Targeted for Binocular Emmetropia or Slight Myopia in the Non - Dominant Eye . - pubmed
Purpose : To evaluate the defocus curve and patient satisfaction after implantation of an extended depth of focus ( EDOF ) toric IOL when both eyes were targeted for emmetropia and when the non - dominant eye was targeted for mini monovision ( -0.50D ) . - pubmed
Subjects presenting for routine cataract surgery were assigned to one of two groups , both receiving bilateral toric EDOF lenses . - pubmed
Measures of interest were the postoperative defocus curve and reported patient satisfaction and visual disturbances . - pubmed
Here , we investigated variations in morphology , including body shape and skeletal deformities , and genetic features among hatchery - born and recaptured A. - pubmed
The diagnosis of pulmonary hypertension before lung resection makes the perioperative management of these patients more difficult and sometimes leads to rejecting patients for surgery . - pubmed
AREAS COVERED : We performed a review of literature on PubMed on Pulmonary hypertension associated lung resection , preoperative assessment of lung resection and perioperative management of PH patients , including guidelines and clinical trials . - pubmed
In this review , we summarize the current state of knowledge regarding the pre and perioperative management of patients with suspected or confirmed PH who can benefit from surgical treatment of lung cancer . - pubmed
EXPERT OPINION : Management of PH patients before lung resection should include a very careful workup including at least right heart catheterization with evaluation of the targeted PH treatment in an expert center and evaluation of other comorbidities . - pubmed
We report a rare case of renal immature teratoma diagnosed in a 6 months old female patient , discuss its pathology and review relevant literature . - pubmed
The present study aimed at selecting non - starter lactic acid bacteria strains , with desirable technological and enzymatic activities , suitable as adjunct culture for the Provola dei Nebrodi cheese production . - pubmed
Among the selected strains , Lacticaseibacillus paracasei PN 76 and Limosilactobacillus fermentum PN 101 were used as adjunct culture in pilot - scale cheese - making trials . - pubmed
The volatile organic compound profiles of experimental cheeses was significantly different from those generated in the controls , suggesting that the selected adjunct strains were able to accelerate the flavour development , contributing to a unique profile of Provola dei Nebrodi cheese . - pubmed
METHODS : AP was induced in wild - type and C3 - deficient mice by retrograde infusion of taurocholate into the pancreatic duct . - pubmed
Identification of patients at risk of IPS decline is of importance as follow - up , treatment and rehabilitation can be optimized . - pubmed
These studies demonstrate that resistance to amikacin in a laboratory strain of E. - pubmed
The relevance of the cholinergic system in mediating hyperactive behaviour in children is discussed . - pubmed
[ Diagnostic characteristics of anthrax in swine ] . - pubmed
Using food - deprived rabbits we investigated the effects of nutritional deficiency on the development of pressure sores . - pubmed
The body weight of these animals was decreased significantly from normal . - pubmed
Protein deficiency in these animals was indicated by serum tests , as well as by histologic features of liver and testis and ultrastructural findings on fibroblasts . - pubmed
Histologic findings at each time were as follows : At day one , the degree of ischemic skin destruction in the malnourished animals was more severe than that in the normal ones , and thrombi were occasionally seen in the malnourished cases . - pubmed
At three days , epidermal cells covered the lesions in the case of normal animals ; however , massive necrosis of the epidermis was still recognized in the malnourished rabbits . - pubmed
Thus , the healing process of pressure sores was strongly suppressed in the malnourished animals . - pubmed
[ Changes in oxygen metabolism during active avoidance learning in spontaneously hypertensive and normotensive rats ] . - pubmed
These changes are enhanced in ageing and most obvious under emotional - motor loads in hypertensive animals . - pubmed
Aortic onchocercosis due to O. - pubmed
Comparative double - blind study of two dosage regimens of low - molecular weight heparin in elderly patients with a fracture of the neck of the femur . - pubmed
A randomized double - blind study comparing the efficacy and safety of two different dosage regimens of a low - MW heparin , Enoxaparin ( Lovenox ) 20 mg twice ( group A ) or 40 mg once ( group B ) , was carried out in 103 elderly patients with a fracture of the neck of the femur . - pubmed
Distal and proximal thrombosis occurred in 18.3 % of patients in group A and in 10.4 % in group B. - pubmed
This trial suggests that a total daily dose of 40 mg of Enoxaparin can be effective in the prevention of deep vein thrombosis in elderly surgically treated patients and does not involve a major risk of bleeding . - pubmed
To determine whether circulating platelets alter during asthmatic reactions induced by allergens , we studied nine subjects previously shown to develop an early or dual asthmatic reaction after inhalation challenge with extracts of house dust mite or grass pollen . - pubmed
Each subject developed an early asthmatic reaction after allergen inhalation challenge , which was followed by a late asthmatic reaction in six subjects and by an equivocal late asthmatic reaction in two of them ( fall in FEV1 of 15 and 17 % respectively ) . - pubmed
Lipolysis in isolated myocardial cells from diabetic rat hearts . - pubmed
Diabetes in rats was induced with streptozotocin ( 100 mg / kg ) ; myocardial cells ( myocytes ) were isolated from the hearts 3 - 4 days later . - pubmed
[ Serotoninergic and catecholaminergic indices in patients with neurotic and depressive disorders and changes in them as a result of reflexotherapy ] . - pubmed
The status of the serotoninergic and catecholaminergic systems was studied in patients with neurotic depressive disorders before and after acupuncture ( AP ) . - pubmed
Prior to AP patients with anxiety - depressive , depressive - hypochondriac or asthenodepressive manifestations showed different changes in the parameters studied . - pubmed
Improvement in biochemical parameters indicates that this type of therapy is an effective means of the treatment of patients with neuroses with the predominance of depressive disorders . - pubmed
Mouse skin photosensitivity with dihaematoporphyrin ether ( DHE ) and aluminium sulphonated phthalocyanine ( AlSPc ): a comparative study . - pubmed
Relationship between serum free thyroid hormone concentrations and target organ responsiveness in thyroid disease patients before and after treatment . - pubmed
Relationship between serum free thyroid hormone concentrations and several markers of peripheral tissue response to thyroid status was studied in 24 patients with hyperthyroidism , 17 with euthyroidism with goiter and 10 with primary hypothyroidism before and after the initiation of standard forms of treatment . - pubmed
These results indicate that these peripheral parameters correlated well with serum free thyroid hormone concentrations in thyroid disease patients . - pubmed
Therefore , these parameters can be used to assess thyroid functions in patients with thyroid hormone resistance . - pubmed
Domestic animals such as dogs can be used as sentinels to provide information on the effects of contaminants in the environment and have been used to a limited extent to evaluate the environmental influences on the occurrence of breast cancer and osteosarcoma . - pubmed
Eight atopic individuals , 3 of whom having mild symptoms , with known birch allergies were selected together with 3 control individuals . - pubmed
volvulus was susceptible to paralysis by CGP 6140 , levamisole , pyrantel and carbachol at concentrations of ten to a thousand times lower than those required to produce any influence on B. - pubmed
The enzyme activity in rat liver increased significantly in the early diabetic , cholesterol - fed , CS 514- , and CPIB - treated groups , but no change in its activity was observed in chronic diabetic groups . - pubmed
When chronic diabetic rats were given a cholesterol diet or treated with CS 514 or CPIB , the activity increased significantly . - pubmed
Lymph node cells from sensitized granuloma - bearing mice with cutaneous anergy showed suppressed specific and nonspecific antigen - induced proliferative responses in vitro . - pubmed
In a series of five experiments , the modulating role of naloxone on a scopolamine - induced retention deficit in a passive avoidance paradigm was investigated in mice . - pubmed
It is postulated that complement activation and glomerulonephritis in staphylococcal endocarditis may be the direct result of a bacterial product . - pubmed
We studied serial brainstem auditory evoked potentials ( BAEPs ) in a patient who had episodic basilar migraine . - pubmed
Seventy eight patients with chronic lung diseases were once or repeatedly vaccinated against influenza with a bivalent inactivated vaccine . - pubmed
Rhizobium meliloti 300hl3 reached the stationary phase of growth very quickly and had an early death when 8.6 muM parathion was added to the growth medium at the start of the culture . - pubmed
Ascending pyelonephritis in dogs induced by ureteral dysfunction . - pubmed
Modified proton relaxation behaviour in erythrocytes from spontaneously hypertensive rats . - pubmed
Diethanolamine salts of the catalytically sulphurated oleic acid ( X-303/1 ) and of the catalytically sulphurated fatty acids isolated from linseed oil ( X-303/2 ) were found to exhibit a strong cytotoxic in vitro activity against Ehrlich ascites cancer cells with minimal cytotoxic effect on normal cells ( leukocytes ) of the peritoneal exudate in rabbits . - pubmed
The Legionnaires ' disease bacterium ( Legionella pneumophila ) inhibits phagosome - lysosome fusion in human monocytes . - pubmed
[ Distant metastases of cervical cancer in patients treated by radiotherapy ] . - pubmed
Defective repair of mitomycin C crosslinks in Fanconi ' s anemia and loss in confluent normal human and xeroderma pigmentosum cells . - pubmed
The immunofluorescence test on paraformaldehyde - fixed cells was used for the detection of antibodies bound to the platelets and granulocytes and present in the sera of 24 patients with Evans syndrome and a further 29 patients with both idiopathic thrombocytopenia ( ITP ) and idiopathic neutropenia ( INP ) , but without autoimmune haemolytic anaemia ( AIHA ) . - pubmed
There is limited experience world wide in the management of patients with cystic fibrosis who undergo thoracotomy . - pubmed
An 8 - year - old boy with cystic fibrosis and a chronic infection of the right lung with abscess formation underwent pulmonary resection after 1 week of antibiotic therapy with tobramycin , ticarcillin and cloxacillin , and physiotherapy . - pubmed
Reduction of reperfusion injury of human myocardium by allopurinol : a clinical study . - pubmed
To determine the possibility of myocardial protection against reperfusion injury by allopurinol , 22 aortocoronary bypass patients were studied . - pubmed
The comparative efficacy of transcatheter arterial chemoembolization and percutaneous ethanol injection ( PEI ) in the treatment of hepatocellular carcinoma ( HCC ) was investigated in a series of 243 consecutive patients : 146 of them were submitted to 1 - 6 chemoembolization sessions at 1 and 3 months ' intervals and 30 to PEI ; the remaining 67 patients refused any treatment . - pubmed
Management and outcome of low - grade astrocytomas of the midline in children : A retrospective review . - pubmed
In the National Toxicology Program 2 - year inhalation study of dichloromethane ( DCM ) , there was a significant increase in pulmonary neoplasms in female B6C3F1 mice exposed to 2000 ppm ( overall rates of 30/48 versus 5/50 in control ) . - pubmed
The patient underwent pterional craniotomy with aneurysm clipping and thrombectomy to relieve mass effect , and has made a good recovery . - pubmed
The treatment of a young man with lumbar spinal tuberculosis and neurological involvement is described . - pubmed
DESIGN AND PATIENTS : This prospective cohort study consisted of 311 inpatients with end - stage congestive heart failure , chronic obstructive pulmonary disease , cancer , and cirrhosis . - pubmed
Active vaccination of patients with HIV infection ( vaccine therapy ) safely alters the immune repertoire against HIV . - pubmed
OBJECTIVE : We describe the unusual syndrome of cytomegalovirus ( CMV ) polyradiculomyelitis and its MR findings in two patients with AIDS . - pubmed
MATERIALS AND METHODS : The clinical records and MRI studies of two patients with AIDS and CMV polyradiculomyelitis were reviewed . - pubmed
CONCLUSION : The clinical presentation of urinary retention , flaccid paraparesis , back and/or leg pain , and " saddle anesthesia " in a patient with AIDS should suggest the diagnosis of CMV polyradiculomyelitis . - pubmed
Although Helicobacter pylori ( HP ) infection has been considered to have an etiologic role in the development of antral gastritis and recurrence of duodenal ulcer , the source and normal route of transmission of HP remains unknown . - pubmed
Similarly RU486 was ineffective in inhibiting lordosis in ovariectomized rats treated only with estradiol ( 3 micrograms of EB / day for 7 days ) . - pubmed
Effect of mild hypothermia on cerebral energy metabolism during the evolution of hypoxic - ischemic brain damage in the immature rat . - pubmed
BACKGROUND AND PURPOSE : Intraischemic hypothermia ( 34 degrees C and 31 degrees C ) has a profound neuroprotective effect on the brain of the immature rat . - pubmed
To determine the mechanisms by which mild to moderate hypothermia affects cerebral energy metabolism of the brain of the newborn rat pup , we examined alterations in cerebral glycolytic intermediates and high - energy phosphate compounds during intraischemic and postischemic hypothermia and correlated these findings with known neuropathologic injury . - pubmed
METHODS : Seven - day - old rat pups underwent unilateral common carotid artery ligation and exposure to hypoxia in 8 % oxygen at either 37 degrees C , 34 degrees C , or 31 degrees C for 3.0 hours . - pubmed
Separate groups were exposed to hypoxia - ischemia at 37 degrees C for 3 hours but recovered at either 37 degrees C , 34 degrees C , or 31 degrees C. At 60 , 120 , and 180 minutes of intraischemic hypothermia and at 10 , 30 , 60 , and 240 minutes of postischemic hypothermia , individual rat pups were quick - frozen in liquid nitrogen for later determination of cerebral concentrations of glucose , lactate , ATP , and phosphocreatine . - pubmed
RESULTS : Cerebral glucose was significantly higher and lactate significantly lower in the 31 degrees C animals during hypoxia - ischemia than either the 34 degrees C or 37 degrees C groups . - pubmed
Postischemic hypothermia of either 34 degrees C or 31 degrees C had no effect on the rate or extent of recovery of glycolytic intermediates or high - energy phosphate compounds compared with the normothermic 37 degrees C rat pups . - pubmed
Thus , the mechanisms by which mild hypothermia is neuroprotective are temperature dependent and may act at more than one point along the cascade of events eventually leading to hypoxic - ischemic brain damage in the immature rat . - pubmed
Continuing transmission of sexually transmitted diseases among patients infected with HIV . - pubmed
Fatty acid ethyl ester ( FAEE ) , a myocardial metabolite of ethanol , causes mitochondrial dysfunction in vitro in rabbits . - pubmed
Small hepatocellular carcinoma in patients with chronic liver damage : prospective comparison of detection with dynamic MR imaging and helical CT of the whole liver . - pubmed
MATERIALS AND METHODS : Fifty patients with chronic hepatitis or liver cirrhosis underwent dynamic contrast - enhanced fast low - angle shot MR imaging and multiple - phase helical CT . - pubmed
Diagnostic ability with both techniques was evaluated by means of receiver operating characteristic ( ROC ) analysis ; images in patients with ( n = 27 ) and those without ( n = 15 ) HCC in whom the same anatomic levels were available for both examinations were assessed . - pubmed
CONCLUSION : Arterial - phase dynamic MR imaging is superior to helical CT for the detection of HCC in patients with chronic liver damage . - pubmed
Against the dogma of the irreversibility of malignant cells , although genetical abnormalities , human leukemic cells have been differenciated . - pubmed
Liver cirrhosis was induced in rats by CCl4 administration . - pubmed
The glomerular filtration rate was slightly decreased in cirrhotic rats but not altered after bosentan treatment in either cirrhotic or control rats . - pubmed
Bosentan decreased sodium excretion to a similar extent in both cirrhotic and control rats , whereas water excretion was significantly reduced by both dosages of bosentan in cirrhotic rats only ( Cir + vehicle : 12.5 + /- 0.62 m day-1 , Cir + 6 mg kg-1 day-1 bosentan : 8.6 + /- 1.0 ml day-1 ; Cir + 100 mg kg-1 day-1 bosentan : 7.4 + /- 0.6 ml day-1 ; n = 10 ; means + /- s.e.mean ) . - pubmed
[ Apoptosis and human viral infections ] . - pubmed
Arrhenius analysis of the thermal response of human colonic adenocarcinoma cells in vitro using the multi - target , single - hit and the linear - quadratic model . - pubmed
In the present paper we demonstrate this discrepancy with the two human colonic adenocarcinoma cell lines WiDr and SW620 . - pubmed
Umbilical cord blood stem cells : application for the treatment of patients with hemoglobinopathies . - pubmed
The review contains a discussion of the potential uses of UCB for patients with hemoglobinopathies and the value of programs designed to collect UCB from newborn infants with hemoglobinopathies , from siblings of patients with hemoglobinopathies , and from groups of ethnic minorities similar to those in which hemoglobinopathies are found . - pubmed
In this paper the Authors present the preliminary results of an investigation of a series of a patients with BPH who have undergone TUIP by modified monolateral incision . - pubmed
From June ' 94 to April ' 96 at the Department of Urology of the Hospital of Matera , 56 patients with BPH - induced cervico - urethral obstruction undergone TUIP . - pubmed
[ Secondary osteoporosis in patients with steroid - dependent asthma ] . - pubmed
The aim of the trial was estimation of frequency and degree of osteoporosis in steroid - dependent asthma patients ( 48 persons : 18 men and 30 women ) . - pubmed
Quantitative computer tomography revealed secondary osteoporosis in 40.5 % asthma patients . - pubmed
PATIENTS AND METHODS : Between 1993 and 1995 , we encountered 15 patients with suspected obturator hernia based on the presence of bowel obstruction of unknown cause and so - called predisposing factors . - pubmed
RESULTS : The 4 patients with bowel obstruction caused by strangulated obturator hernia were all correctly diagnosed preoperatively by ultrasonography and were successfully cured by surgery . - pubmed
Mesenchymal hamartoma in a 21 - year - old man . - pubmed
in conscious dogs with chronic atrioventricular block and ventricular pacing at 50 to 130 beats / min . - pubmed
We have studied mucosal tolerance in autoimmune diabetes using the non - obese diabetic mouse model . - pubmed
A similar outcome was obtained when patients were stratified by cytogenetics into FIPC and UC groups . - pubmed
Patients with FIPC and a lower ratio ( less than median ) of either B2 : BX or PK*B2 : BX had a significantly higher remission induction rate ( 88 versus 69 % , P = 0.04 ) and longer survival ( median : 141 versus 80.5 weeks , P = 0.007 ) compared with those with ratios more than median . - pubmed
For patients with UC , values of either B2 : BX or PK*B2 : BX below the median had an inferior response rate to induction therapy ( 35 versus 78 % , P = 0.0006 ) and inferior survival outcomes ( median survival : 11 versus 53 weeks , P = 0.00002 ) . - pubmed
Chronically cannulated conscious rats were subjected to 40 ml / kg of hemorrhage and resuscitated with the shed blood and twice the volume of saline either under room air ( room air group ) or under 100 % oxygen at 3 atmospheres absolute ( hyperbaric group ) . - pubmed
Rats exposed to HBO with no hemorrhage served as controls . - pubmed
In the present study , we have examined neurochemical correlates that may be involved in the differential cardiovascular responses observed in normotensive and hypertensive rats during stress . - pubmed
Using a restraint stress paradigm , both normotensive Wistar Kyoto ( WKY ) and Spontaneously Hypertensive rats ( SHR ) underwent acute ( 1 h restraint in a perspex tube ) , chronic ( 1 h restraint for ten consecutive days ) or no restraint ( control ) stress . - pubmed
Male Wistar rats ( n = 20 , 4 mo old ) and 20 male Bio Breeding Wistar ( BB / W ) rats of the same age were used ; the Wistar rats represent the control non - diabetic rats while the BB / W rats represent the diabetic group . - pubmed
The most interesting aspects of parathyroid disease are the increased incidence of primary hyperparathyroidism , which nowadays is diagnosed more and more frequently through the casual discovery of hypercalcaemia , the various diagnostic methodologies used , the ongoing debate as to the function of parathyroidectomy in asymptomatic patients and the new video - assisted surgical techniques which have recently been developed . - pubmed
There were no cases of mortality , and 9.6 % of patients presented specific morbidity characterised by some degree of paraesthesia . - pubmed
OBJECTIVE : To report a case of successful treatment of refractory hot flashes with gabapentin in a patient with prostate cancer who was receiving combination antiandrogen and gonadotropin hormone - releasing hormone ( GnRH ) analog therapy . - pubmed
CASE SUMMARY : A 70 - year - old white man with a history of advancing prostate cancer experienced disabling hot flashes from combination therapy with the antiandrogen bicalutamide and the GnRH analog goserelin acetate . - pubmed
CONCLUSIONS : Hot flashes resulting from antiandrogen or GnRH analog therapy are often difficult to treat and leave many patients disabled . - pubmed
[ Hematogenous ( suspected-)septic inflammation of the synovial fossa in the adult horse : rare but deceptive ( 3 case reports ) ] . - pubmed
Septic inflammation of the synovial fossa in the horse is a severe disorder that can lead to permanent invalidity . - pubmed
Three cases of suspected haematogenous septic synovitis are described in adult horses ( older than 1 year ) . - pubmed
In two horses , timely and adequate treatment resulted in recovery , but this was followed by fatal recurrence . - pubmed
In one of these horses a persistent primary infection was found as cause ; the other horse was not available for autopsy . - pubmed
It can be concluded that , in horses with suspected haematogenous septic inflammation of the synovial fossa , attention should be paid to the primary process -- it is not enough to treat the synovitis alone . - pubmed
PURPOSE : To determine whether the patient - based assessment of difficulty in mobility , developed and validated in a group of patients with retinitis pigmentosa ( RP ) , is valid for measuring perceived visual ability for independent mobility in patients with glaucoma . - pubmed
METHODS : A mobility questionnaire that had previously been developed was administered to 83 patient - volunteers who had various amounts of visual impairment caused by glaucoma . - pubmed
These studies characterize drug - specific T cells in CBZ - hypersensitive patients that are phenotypically different from T cells involved in other serious cutaneous adverse drug reactions . - pubmed
Over the last two decades , several studies have reported a high prevalence of cardiovascular disease in patients with end - stage renal disease ( ESRD ) . - pubmed
Until larger RCTs of longer duration , which correct the existing methodological flaws , are designed and carried out , it is best not to recommend garlic be used to treat mild to moderate hyperlipidemia . - pubmed
[ MENINGOCOCCAL INFECTIONS ARE DISTRIBUTED OVER THE WHOLE YEAR ] . - pubmed
BACKGROUND : Adverse reactions to nonsteroidal anti - inflammatory drugs ( NSAIDs ) are frequent , particularly among patients with chronic urticaria or asthma . - pubmed
METHODS : We studied 216 patients ( 164 females and 52 males ) who had suffered adverse reactions to one or more NSAIDs ; 98 subjects ( 45.4 % ) had experienced reactions to only one NSAID ( single hypersensitivity ) and 118 subjects ( 54.6 % ) had reacted to multiple NSAIDs ( multiple hypersensitivity ) . - pubmed
Cutaneous reactions were reported by 79.6 % of the subjects , respiratory symptoms by 10.7 % , cutaneous and respiratory symptoms by 8.3 % , anaphylaxis by 1.4 % . - pubmed
CONCLUSIONS : Considering previous studies and our own data , rofecoxib was well tolerated by all of the 174 patients with exclusively NSAID - related respiratory symptoms . - pubmed
[ Serum homocysteine , vitamin B12 and folic acid concentrations in patients with alcoholic liver cirrhosis ] . - pubmed
The aim of the work was to establish serum homocysteine , vitamin B12 and folic acid concentrations in patients with alcoholic liver disease . - pubmed
Hyperhomocysteinemia ( concentration & gt ; 12 mmol//l ) was stated in 50 % of the patients and mean homocysteine concentration was statistically significantly higher if compared to the controls ( 13.29 + /- 8.16 vs 11.03 + /- 1.6 mmol / l p & lt ; 0.05 ) . - pubmed
A negative correlation between homocysteine concentration and folic acid concentration in the group of the patients with hyperthomocysteinemia was observed ( r = -0.88 , p & lt ; 0.001 ) and among all the patients ( r = -0.312 , n.s . ) - pubmed
Correction of disturbed respiratory function and inhibition of progression of pulmonary inflammatory and obstructive processes is the aim of respiration rehabilitation in patients with chronic bronchitis ( CB ) . - pubmed
It is known that rehabilitation in CB patients with spinal diseases meets with difficulties as dystrophic lesions of the spine entail its functional - anatomic disorders at the corresponding level . - pubmed
New approaches to rehabilitation of CB patients with spinal lesions lie in use of pharmacopuncture , acupuncture , deep reflex - muscular massage and therapeutic exercise in consensual sequence . - pubmed
This agent appears to be particularly promising clinically in the treatment of reperfusion injury , for example in combination with reperfusion strategies during the acute phase of myocardial ischemia or infarction , or in the reduction of the pro - remodeling effects of ischemia in patients with chronic ischemic syndrome and left ventricular dysfunction . - pubmed
The induction of acute ileitis by a single microbial antigen of Toxoplasma gondii . - pubmed
Oral infection of susceptible C57BL/6 mice with Toxoplasma gondii results in a lethal ileitis within 7 - 9 days postinfection . - pubmed
C57BL/6 mice orally infected with Deltasag1 parasites failed to develop ileitis . - pubmed
RAG - deficient ( RAG1 (-/- ) ) mice are resistant to the development of the ileitis after T. - pubmed
In addition , resistant mice ( BALB / c ) that fail to develop ileitis following oral infection with T. - pubmed
Impella Recover 100 : successful perioperative support for off pump coronary artery bypass grafting surgery in a patient with end - stage ischemic cardiomyopathy . - pubmed
The authors present the successful use of the Impella recover 100 intracardiac left ventricular assist device in a 55 - year old man suffering from end - stage ischemic cardiomyopathy . - pubmed
[ Botulinic toxin in patients with neurogenic dysfunction of the lower urinary tracts ] . - pubmed
Botulinic toxin ( BT ) is a new method of lowering intraurethral pressure in symptoms of obstructive voiding in patients with neurogenic dysfunction of the lower urinary tracts ( LUT ) . - pubmed
Transperineal introduction of 100 units of BT type A ( botox , Allergan ) was used under electromyographic control into the external urethral sphincter of 9 patients ( 6 males and 3 females ) with LUT neurogenic dysfunction aged 17 to 68 years ( mean age 37.2 years ) . - pubmed
Two patients had subnormal detrusor contractility due to myelodysplasia and diabetic polyneuropathy , two other patients -- non - incontinent striated urethral sphincter after hemorrhagic stroke and spinal contusion , five patients suffered from detrusor - sphincteral dyssynergia ( DSD ) resultant from Schmorl ' s hernia , multiple sclerosis , Charcot - Marie disease and ischemic stroke of the spinal cord . - pubmed
In 10 days residual urine was not found in 2 patients with subnormal detrusor contractility and in 4 patients with DSD . - pubmed
Mean maximal urinary flow rate rose from 4.3 to 9.6 ml / s. In 20 days , on the average , suprapubic fistula healed in all the patients . - pubmed
Electroretinographic examinations were made in 191 patients with non - proliferative and pre - proliferative diabetic retinopathy . - pubmed
Several studies in a variety of breeds have reported at least two QTL for milk production traits , including milk fat synthesis on bovine chromosome 6 ( BTA6 ) , comprising a region that comparatively has been mapped to equivalent syntenic chromosome intervals in human , pig , and mouse harboring loci associated with type II diabetes and obesity - related traits . - pubmed
METHODS : Colitis was induced by oral administration of dextran sodium sulfate ( 5 % ) to C57BL / 6 mice for 7 days . - pubmed
Aspects of the phenomenon which are discussed include physiological changes and their anatomical location , the effects of total and selective sleep deprivation in the human and animal , and REM sleep behavior disorder , the latter with its clinical manifestations in the human . - pubmed
We report the case of a 65 - year - old man WDK , who experienced selective loss of timbre perception for keyboard and percussion instruments following a right temporal stroke comprising the anterior superior and medial gyrus and parts of the insular region . - pubmed
To identify potential factors mediating drug resistance to melanoma cells , the mRNA expression profiles of the parental drug - sensitive human melanoma cell line MeWo and four derived drug - resistant sublines with acquired resistance against four commonly used drugs for melanoma treatment ( cisplatin , etoposide , fotemustine and vindesine ) were analysed . - pubmed
[ Combining high - risk human papillomavirus DNA test and cytological test to detect early cervical dysplasia ] . - pubmed
OBJECTIVE : To assess the value of combining high - risk human papillomavirus ( HPV ) DNA test and cytological test in detection of early cervical dysplasia . - pubmed
Based on the criteria of histology and pathology , the sensitivity , specificity , positive - predictive value and negative - predictive value of high - risk HPV DNA test for detecting all cases of CIN II , III were 92.22 % , 74.71 % , 5.19 % and 99.84 % respectively . - pubmed
METHODS : Epilepsy patients on VPA - DR were offered the chance to convert to VPA - ER . - pubmed
Early paracentral visual field loss in patients taking hydroxychloroquine . - pubmed
Thirty - five patients ( 13.4 % ) had visual field abnormalities , which were attributed to hydroxychloroquine treatment in 4 patients ( 1.5 % ) . - pubmed
The effect of surgery on quality of life in patients with faecal incontinence of obstetric origin . - pubmed
OBJECTIVE : To evaluate the results of surgery in the treatment of faecal incontinence of obstetric origin and assess the effect of treatment on the quality of life of these patients . - pubmed
PATIENTS AND METHODS : A consecutive series of 43 patients , who had undergone surgery for severe faecal incontinence of obstetric aetiology between March 1990 and March 2004 , was studied . - pubmed
CONCLUSION : Surgical treatment of faecal incontinence of obstetric origin achieves good results in a high percentage of patients and has a positive effect on their quality of life . - pubmed
BACKGROUND : There is a growing interest for the use of local ablative techniques in patients with non - resectable colorectal liver metastases . - pubmed
METHODS : A consecutive series of 201 colorectal cancer patients , without extrahepatic disease , that underwent laparotomy for surgical treatment of liver metastases , were prospectively followed for survival and HRQoL. - pubmed
At laparotomy three groups were identified : patients in whom radical resection of metastases proved feasible , patients in whom resection was not feasible and received local ablative therapy , and patients in whom resection or local ablation was not feasible for technical reasons and who received systemic chemotherapy . - pubmed
Oral rabies vaccine ( ORV ) bait uptake by captive striped skunks . - pubmed
Aerial delivery of oral rabies vaccine ( ORV ) baits has proven effective in large - scale efforts to immunize wildlife against rabies , and in North America this strategy currently is being used to immunize foxes ( Urocyon cinereoargenteus and Vulpes vulpes ) , raccoons ( Procyon lotor ) , and coyotes ( Canis latrans ) . - pubmed
Skunks are also a major reservoir and vector of rabies , but at present oral vaccines for use in skunks are not licensed . - pubmed
BACKGROUND : Patients with unicompartmental osteoarthritis of the knee can be treated with a correction osteotomy . - pubmed
A successful outcome of the osteotomy relies on proper patient selection , stage of osteoarthritis , achievement and maintenance of adequate operative correction . - pubmed
SELECTION CRITERIA : Randomised and controlled clinical trials comparing a high tibial osteotomy or a distal femoral osteotomy in patients with unicompartmental osteoarthritis of the medial or lateral compartment of the knee . - pubmed
MAIN OUTCOME MEASURE : We observed the patients for 5 months and compared the occurrence rate of synechia formation between the 2 groups . - pubmed
Pyruvate reduces in vitro the embryotoxic effect of peritoneal fluid from infertile women with endometriosis . - pubmed
OBJECTIVES : To ascertain the embryotoxicity of peritoneal fluid from infertile women with endometriosis ( PF - E ) , on mouse embryos in culture and to examine the effect of pyruvate in the culture medium on PF - E induced embryotoxicity . - pubmed
STUDY DESIGN : Blood - free peritoneal fluid samples were obtained during laparoscopic investigation for infertility from 21 infertile women with endometriosis . - pubmed
They were then cultured in modified Whitten 's medium ( mWM ) with peritoneal fluid from patients with endometriosis , and either in the absence or presence of excess pyruvate ( 0.062 mmol(-1 ) ) . - pubmed
Urinary tract calculi in recumbent patients . - pubmed
In this article , we report an interesting case of a young woman who presented with this rare type of reverse apical ballooning syndrome occurring after amphetamine use . - pubmed
[ Cognitive performances in workers with chronic virus hepatitis ( HBV - HCV ) ] . - pubmed
The sample of 21 workers suffering from chronic viral hepatitis in drug treatment has been studied with a battery of standardized tests to assess the cognitive performance , the neurobehavioral effects and psychological disorders that interfere with quality of life , comparing the results of subjects with HBV with those of subjects suffering from HCV . - pubmed
The results showed that both subjects with chronic HBV and HCV have relational - work restrictions that determine long periods of absence from the workplace , with the depression , anxiety , irritability and dysphoria . - pubmed
It is that in patients with chronic HCV physical functioning is significantly impaired with clinical manifestations of the disease that lead to major depression and deficit cognitive function . - pubmed
22 subjects diagnosed with AD , mean Mini Mental State Exam ( MMSE ) score 22.2 , and 16 healthy elderly controls were imaged with a volumetric arterial spin labeling blood flow MRI technique and an anatomical imaging method using the identical spatial resolution , image orientation , and spatial encoding strategy . - pubmed
CONCLUSION : In this article , we outline the technique of thoracoscopic resection of paraspinal neurogenic tumors through an operative video and a review of the literature to summarize the surgical outcomes of patients with these lesions . - pubmed
We divided individuals into three groups according to plasma homocysteine levels and compared their risk for the development of new and progression of existing OA . - pubmed
Visual hallucinations in a patient with adult onset acid maltase deficiency disorder . - pubmed
A 66 - year - old male presented with visual hallucinations . - pubmed
METHODS : We studied 18 severely obese but otherwise healthy men . - pubmed
Overall , the anatomic form - stable silicone gel breast implants , when placed sub fascially , improve common complications such as capsular contracture and implant rupture with improved aesthetic outcomes and patient satisfaction . - pubmed
METHODS : One hundred patients with histologically proven adenocarcinoma of the lung were included in this retrospective analysis . - pubmed
Our findings suggest that the percentage SUVmax change over time is a strong prognostic factor in patients with lung adenocarcinoma and can be complementary to the other well - known factors . - pubmed
Prospective longitudinal studies of head - injured individuals , with neuropathological verification , will not only improve understanding of head trauma as a risk factor for dementia but will also enhance treatment and prevention of a variety of neurodegenerative diseases . - pubmed
Various preparations of estrogen and progestogen are prescribed for young women with POF . - pubmed
A matched prospective cohort study on Staphylococcus aureus and Escherichia coli bloodstream infections : extended perspectives beyond resistance . - pubmed
BACKGROUND : Bacteremias caused by Staphylococcus aureus and Escherichia coli are among the most common bloodstream infections ( BSIs ) in adults . - pubmed
The aim of the study was to investigate risk factors for infection and clinical outcomes of bacteremias caused by S aureus or E coli . - pubmed
METHODS : We conducted a 1 - year matched prospective cohort study including 150 patients with BSI caused by susceptible or resistant S aureus or E coli and 300 controls without BSI caused by these organisms . - pubmed
We identified 4 independent risk factors for acquisition of S aureus bacteremia ( emergency , peripheral or central vascular catheter , renal disease ) and 6 risk factors for E coli bacteremia ( emergency , peripheral or central vascular catheter , malignancy , cytoreductive or immunosuppressive therapy ) . - pubmed
We observed a 5 - fold increase in the 30 - day mortality rate for bacteremias due to S aureus , and a 2 - fold increase in BSI caused by E coli . - pubmed
CONCLUSION : Longer hospitalization periods and increased mortality of bacteremias caused by S aureus or E coli , irrespective of susceptibility , implicate controlling for risk factors at an early stage . - pubmed
However , few studies have examined gait in PD patients who fall . - pubmed
This study reports on the complexities of walking in PD patients who reported falling during a 12 - month follow - up . - pubmed
Forty - nine patients clinically diagnosed with idiopathic PD and 34 controls had their gait assessed using three - dimensional motion analysis . - pubmed
anti-1 - Amino-3 -[( 18 ) F ] fluorocyclobutane-1 - carboxylic acid ( anti-[( 18 ) F ] FACBC ) was shown to have a high tumor / brain ratio ( 8) , and anti-[( 18 ) F ] FACBC has been studied in humans with PET tumor imaging ( 9 ) . - pubmed
Adjuvant carboplatin and gemcitabine combination chemotherapy postamputation in canine appendicular osteosarcoma . - pubmed
BACKGROUND : Appendicular osteosarcoma ( OSA ) , the most common bone tumor in dogs , is typically treated by amputation and adjuvant chemotherapy . - pubmed
Evidence from studies in mice suggests that gemcitabine has activity against OSA in vivo . - pubmed
ANIMALS : Fifty dogs with histologically confirmed appendicular OSA . - pubmed
Dogs with proximal humeral OSA had a shorter median DFI ( P = .04 ) compared with dogs with OSA in other locations . - pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : These results are comparable to those reported for carboplatin monotherapy indicating that the addition of gemcitabine to carboplatin in dogs with appendicular OSA does not appear to improve outcome . - pubmed
Successful cochlear implantation in a patient with MNGIE syndrome . - pubmed
Abstract A 28 - year - old woman with mitochondrial neurogastrointestinal encephalomyopathy ( MNGIE syndrome ) undergoing evaluation for multichannel cochlear implantation is described . - pubmed
Characterization of spontaneous subclavian steal phenomenon in a female rhesus macaque ( Macaca mulatta ) . - pubmed
Although SSP is a common echographic finding in humans , the phenomenon occurs only rarely in animals ; consequently its physiologic features have not been reported previously . - pubmed
Here we describe the clinical and morphologic features of a spontaneous left SSP that was an incidental finding in an 18 - y - old female rhesus macaque ( Macaca mulatta ) . - pubmed
Populations of tetraploid D. - pubmed
An antimicrobial , antithrombotic lock solution reduced catheter - related bloodstream infections in patients receiving dialysis . - pubmed
BACKGROUND : Several agents are available to treat osteoporosis while addressing patient - specific medical needs . - pubmed
Individuals ' residual risk to severe fracture may require changes in treatment strategy . - pubmed
Our study on a series of five consecutively taken bone biopsies from an osteoporotic individual over a six - year period analyzes changes in cellular characteristics , bone microstructure and mineralization caused by a therapy switch from an antiresorptive ( bisphosphonate ) to a dual action bone agent ( strontium ranelate ) . - pubmed
[ Long - term prognosis in patients with acute non - ST - segment elevation myocardial infarction depending on dynamics of tissue myocardial dopplerography ] . - pubmed
MATERIAL AND METHODS : MTD echocardiography was conducted in 88 non - ST elevation AMI ( mean age 58.0 - 9.8 years ) and 34 healthy volunteers ( mean age 58.0 + /- 9.8 years ) . - pubmed
CONCLUSION : The treatment of non - ST elevation AMI reduces the number of patients with a diffuse decrease of MTD values and elevates the number of patients with asymmetric decrease of MTD and unchanged MTD . - pubmed
In vivo imaging of stepwise vessel occlusion in cerebral photothrombosis of mice by 19F MRI . - pubmed
In the present study we compared ( 19 ) F MRI with iron - enhanced MRI in mice with photothrombosis ( PT ) at 7 Tesla . - pubmed
By sequential administration of two chemically shifted PFC compounds 0 and 2 hours after illumination the different spatial distribution of the ( 19 ) F markers ( infarct core / rim ) could be visualized in the same animal . - pubmed
[ Antisynthetase syndrome : a retrospective study of 14 patients ] . - pubmed
PATIENTS AND METHODS : Fourteen patients with antisynthetase syndrome followed - up between 1997 and 2009 were included . - pubmed
Seven patients had myositis . - pubmed
After a mean follow - up of 64 months , nine patients improved , four stabilized and one patient died after lung transplantation , required for pulmonary hypertension . - pubmed
We reviewed previous studies of subjects in a prodromal stage of psychosis and tested cingulate volume changes during the transition to psychosis . - pubmed
METHODS : A cross - sectional MRI study of manually traced cingulate gray - matter volumes in 37 individuals with an at risk mental state ( ARMS ) for psychosis , 23 individuals with a first - episode psychosis ( FEP ) , and 22 healthy controls ( HC ) was performed using a 1.5 T MRI - scanner . - pubmed
RESULTS : Compared to HC , subjects with an ARMS had significantly reduced left caudal anterior cingulate cortex volume ( p & lt ; 0.027 ) . - pubmed
MATERIAL AND METHODS : We included in the study 1005 patients with coronary artery disease and normal serum creatinine . - pubmed
CONCLUSIONS : In our study we found a very high prevalence of CKD up to 61 % in elderly patients with coronary artery disease and normal serum creatinine . - pubmed
A preliminary investigation of corpus callosum and anterior commissure aberrations in aggressive youth with bipolar disorders . - pubmed
METHOD : DTI was used to investigate WM in 10 youth ( 7 - 17 years of age ) with BPD and 10 typically developing age - matched controls . - pubmed
CONCLUSIONS : These results contribute to a growing literature implicating a role for the genu of the CC in BPD and are the first to report WM variations in the AC of children with BPD . - pubmed
Here , we enabled global processing in patients with simultanagnosia using a psychophysical technique , which allowed us to bias stimuli such that they are processed predominantly by the intact ventral visual pathway . - pubmed
Minor complications were skin reaction only in 2 patients ( 6 % ) . - pubmed
The aim of this retrospective study was to present our own experience with 5 children affected with C - RE , emphasizing the differences in clinical picture and low sensitivity of ultrasound images . - pubmed
PATIENTS AND METHODS : A 67 - year - old woman was hospitalized for flank pain ; imaging studies revealed a 6.5 - cm mass in the right kidney . - pubmed
papillary RCC with sarcomatoid transformation ) is important for predicting patient prognosis . - pubmed
Even though not explored in this manuscript , the impact that the results presented here may have on the development of gastritis , warrant further research to understand the underlying mechanisms of the relationship between H. - pubmed
Careful long - term follow - up is essential even in patients with benign pheochromocytoma . - pubmed
Vitamin D levels and insulin resistance in children born with severe growth restriction . - pubmed
In conclusion , at prepuberty severely in utero growth restricted children have increased birth weight dependent levels of 25 ( OH ) D , which might exert a regulatory role on beta - cell function . - pubmed
Relapse of herpes encephalitis induced by temozolomide - based chemoradiation in a patient with malignant glioma . - pubmed
Careful observation for HSE is necessary when administering chemoradiation to patients with a history of HSE . - pubmed
The therapeutic drug monitoring of paroxetine could be used to optimize the pharmacological treatment of depressed patients . - pubmed
Moreover , under the optimal fermentation conditions in a 7.5 l fermenter , the MCR production of MX3004 reached the maximum of 263 U / ml , which was increased by 484 % compared with the parent strain . - pubmed
METHODS : A total of 1,681 patients were diagnosed preoperatively with unilateral inguinal hernia . - pubmed
All patients underwent laparoscopic inguinal hernia transabdominal preperitoneal ( TAPP ) repair . - pubmed
Patients with an evident occult hernia received immediate repair . - pubmed
Patients with a smaller beginning or incipient hernia were followed . - pubmed
All patients with an incipient hernia were followed . - pubmed
METHODS AND MATERIALS : We selected patients treated for localized prostate cancer with brachytherapy , combination therapy with external beam radiotherapy , and adjuvant androgen deprivation therapy as prescribed by our Mount Sinai risk stratification and treatment algorithm . - pubmed
CONCLUSIONS : Brachytherapy , as administered via the Mount Sinai algorithm , remains an efficacious and benign treatment option for patients with localized prostate cancer of all risk groups . - pubmed
Bovine colostrum improves intestinal function following formula - induced gut inflammation in preterm pigs . - pubmed
BACKGROUND & amp ; AIMS : Only few hours of formula feeding may induce proinflammatory responses and predispose to necrotizing enterocolitis ( NEC ) in preterm pigs . - pubmed
CONCLUSIONS : Bovine colostrum restores intestinal function after initial formula - induced inflammation in preterm pigs . - pubmed
Further studies are required to test if bovine colostrum may also benefit preterm infants during the challenging transition from total parenteral nutrition to enteral nutrition , when human milk is unavailable . - pubmed
METHODS : A total of 118 429 subjects without diabetes ( 70 980 men and 47 449 women ) , aged 17 - 90 years ( mean age 39.6 years ) , were enrolled in this study and followed for a mean duration of 3.1 years . - pubmed
Patients with a poor prognosis histologic subtype or peritoneal carcinosis were excluded . - pubmed
One hundred ninety - nine patients had squamous carcinoma , and 38 had adenocarcinoma / adenosquamous lesions . - pubmed
The anti - obesity effects of the dietary combination of fermented red ginseng with levan in high fat diet mouse model . - pubmed
In this study , to evaluate the anti - obesity effects of fermented red ginseng ( FG ) , levan ( L ) , and their combination ( FGL ) , we investigated their effects on the weights of body , liver and white adipose tissue , lipid profiles , and biomarkers for insulin resistance in high fat diet ( HFD)-induced obese C57BL/6J male mice . - pubmed
After 11 weeks feeding , FGL showed significantly lower body weight and fat mass with decreasing food efficiency ratio than the HFD control mice . - pubmed
Nevertheless , there are cases of successful ECMO application in patients with multiple trauma and hemorrhagic shock or head trauma and intracranial hemorrhage . - pubmed
We successfully applied ECMO in a 65 - year - old woman with acute life - threatening respiratory failure due to diffuse massive pulmonary hemorrhage secondary to granulomatosis with polyangiitis , manifested as severe pulmonary - renal syndrome . - pubmed
RESULTS : 20 subjects were diagnosed with well - differentiated liposarcoma ( WLS ) , 16 myxoid liposarcoma ( ML ) , 7 pleomorphic liposarcoma ( PL ) , and 5 de - differentiated liposarcoma ( DLS ) . - pubmed
This is the first report to identify Group A Streptococcus emm type-89 as a cause of tonsillopharyngitis in Beijing , China . - pubmed
Deaths occurred in 7 patients . - pubmed
PATIENTS AND METHODS : We retrospectively evaluated patients with intramural pseudocysts seen at our institution over the past 6 years . - pubmed
Depending upon the symptoms , their control with the conservative medical therapy and procedural consent , the patients underwent EUS guided single time aspiration of the pseudocyst or transmural drainage or transpapillary drainage or surgery . - pubmed
RESULTS : A total of 9 patients with intra mural pseudocysts ( male : n = 8 ; mean age + - SD : 39.3 + - 8.0 years ; age range : 24 - 54 years ; five patients having chronic and four patients having acute pancreatitis ) were studied . - pubmed
The pseudocysts were located in the wall of the second part of the duodenum in five patients , in the gastric wall in three patients and in the lower esophageal wall in one patient . - pubmed
All patients had abdominal pain on presentation . - pubmed
Along with pain the patients with duodenal intramural pseduocysts also had symptoms suggestive of gastric outlet obstruction ( 3 ) or jaundice ( 1 ) . - pubmed
Transcriptomic analysis of Prunus domestica undergoing hypersensitive response to plum pox virus infection . - pubmed
One variety of Prunus domestica , named ' Jojo ' , develops a hypersensitive response to viral infection . - pubmed
The combination of next - generation sequencing and a Prunus variety that develops a hypersensitive response to PPV infection provided an opportunity to study the factors involved in this plant defense mechanism . - pubmed
BACKGROUND : Macroscopic cytoreductive surgery and hyperthermic intrathoracic chemotherapy perfusion ( HITHOC ) is a new multimodal approach for selected patients with primary and secondary pleural tumors , which may provide the patient with better local tumor control and increased overall survival rate . - pubmed
Only two patients ( 10 % ) showed an impairment of coagulation in postoperative laboratory analysis . - pubmed
Growth retardation and growth hormone deficiency in patients with Ataxia telangiectasia . - pubmed
BACKGROUND : Ataxia telangiectasia ( A - T ) is a devastating human recessive disorder characterised by progressive cerebellar ataxia , immunodeficiency , genetic instability , and cancer susceptibility . - pubmed
In addition , many patients suffer from growth failure . - pubmed
Recent recognition of these effector cells in immune regulations , host defense against bacteria and virus , and autoimmune diseases entices increased interest in studying these cells . - pubmed
Plants treated with 5 mM ALA or 50 microM OF exhibited differential herbicidal symptoms as characterized by white and brown necrosis , respectively , with substantial increases in cellular leakage and malondialdehyde production . - pubmed
Effect of neurotoxic lesion of pedunculopontine nucleus in nigral and striatal redox balance and motor performance in rats . - pubmed
RESULTS : During the exponential growth phase ( log ) of bacterial strains , a lineal correlation between luminous activity vs biomass was observed ( R(2 ) = 0.985 , 0.976 , 0.981 ) for E. - pubmed
Posttransplantation diabetes mellitus ( PTDM ) is a major complication after renal transplantation due to its negative impact on patient and graft survival , and affects up to 40 % of renal transplant recipients . - pubmed
This review will discuss the significance of the standard diagnostic criteria for DM in patients after renal transplantation without prior DM . - pubmed
The ketogenic diet ( KD ) is an effective alternative treatment for refractory epilepsy in children , but the mechanisms by which it reduces seizures are poorly understood . - pubmed
METHODS : Ten patients with plasma cell - rich chronic inflammatory conditions of the oral mucosa were identified ( seven -- plasma cell mucositis and three -- non - specific diffuse oral mucosal inflammation with ulceration ) . - pubmed
Hence , ethidium bromide was used in a rat model to evaluate the positive effects of Dl-3 - n - butylphthalide in demyelinating diseases . - pubmed
CONCLUSIONS : In vitro addition of idarucizumab to plasma samples containing dabigatran fully neutralizes the drug , and facilitates the use of routine coagulation assays to allow the diagnosis of hemostasis disorders that may be concurrently present in patients taking dabigatran . - pubmed
Here we address this question by testing 32 adults with generalized anxiety disorder ( 15 GAD only and 17 comorbid MDD ) and 25 healthy controls ( HC ) using multimodal MRI ( structure , diffusion and functional ) and automated hippocampal segmentation . - pubmed
We found that only the mice that lacked the interstitial region developed prostate adenocarcinomas marked by poor differentiation and epithelial - to - mesenchymal transition . - pubmed
RATIONALE : Obstructive sleep apnea ( OSA ) is common in patients with coronary artery disease ( CAD ) , many of whom do not report daytime sleepiness . - pubmed
First - line treatment for symptomatic OSA is continuous positive airway pressure ( CPAP ) , but its value in patients without daytime sleepiness is uncertain . - pubmed
OBJECTIVES : To determine the effects of CPAP on long - term adverse cardiovascular outcome risk in patients with CAD with nonsleepy OSA . - pubmed
Consecutive patients with newly revascularized CAD and OSA ( apnea - hypopnea index & gt;=15 / h ) without daytime sleepiness ( Epworth Sleepiness Scale score & lt;10 ) were randomized to auto - titrating CPAP ( n = 122 ) or no positive airway pressure ( n = 122 ) . - pubmed
CONCLUSIONS : Routine prescription of CPAP to patients with CAD with nonsleepy OSA did not significantly reduce long - term adverse cardiovascular outcomes in the intention - to - treat population . - pubmed
Inpatients aged 0 to 9 years experienced higher rates of airway and respiratory complications , peaking at an odds ratio of 7.5 ( 95 % CI , 3.1 - 18.2 ) for airway complications in the group aged 0 to 11 months . - pubmed
Fetal alcohol syndrome ( FAS ) is a condition resulting from excessive drinking by pregnant women . - pubmed
In ethanol - treated mice , there was a reduction in brain size and decreased neuronal cell number in the cortex , and also cognitive impairment . - pubmed
MATERIALS AND METHODS : At 3 T , relative pCASL labeling efficiency was experimentally assessed in five subjects by measuring the signal intensity of blood in the popliteal artery just distal to the labeling plane immediately following pCASL labeling or control preparation pulses , or without any preparation pulses throughout separate ischemia - reperfusion paradigms . - pubmed
In a separate cohort of 10 subjects , pCASL and PASL sequences were used to measure reactive hyperemia perfusion dynamics . - pubmed
PARTICIPANTS : Postmenopausal women diagnosed with hip fracture ( n = 335 ) and matched controls without fracture ( n = 335 ) . - pubmed
This case demonstrates the usefulness of genomic analysis in establishing the diagnosis of DBA in patients with a nonclassical presentation of the disease . - pubmed
Although the incidence of cardiovascular diseases classically associated with human immunodeficiency virus ( HIV ) has decreased considerably with antiretroviral therapy , cardiovascular risk , and especially ischemic heart disease , are higher in HIV - infected patients than in uninfected individuals . - pubmed
Currently , it is not uncommon to find HIV patients with acute coronary syndrome and , given the important pharmacokinetic interactions of antiretroviral drugs , it is important to know which cardiovascular treatments are safe in this group of patients . - pubmed
All these issues are discussed in this review , which aims to aid clinical cardiologists faced with HIV patients with ischemic heart disease or with high cardiovascular risk in daily clinical practice . - pubmed
This study was aimed at assessing the role of Posthorax support vest ( Epple , Inc. , Vienna , Austria ) in the prevention of sternal complications and the improvement of anatomical healing in patients at high risk for mechanical sternal dehiscence after cardiac surgery by mean of median sternotomy . - pubmed
METHODS : A prospective , randomized , study was performed and 310 patients with predisposing factors for sternal dehiscence after sternotomy for cardiac surgery were included . - pubmed
RESULTS : Patients using vest demonstrated a lower incidence of mechanical sternal complications , a better anatomical sternum healing , lower hospital stay , no re - operations for sternal dehiscence before discharge and lower re - admissions for mechanical sternal complication . - pubmed
Atomoxetine treatment for children and adolescents with Attention - Deficit / Hyperactivity Disorder ( ADHD ): a comprehensive meta - analysis of outcomes on parent - rated core symptomatology . - pubmed
Attention - Deficit / Hyperactivity Disorder ( ADHD ) impacts a significant number of children and adolescents and often leads to deleterious functional impairment . - pubmed
METHODS : A total of 254 male patients with CAD and 122 male controls were recruited for this study . - pubmed
Zebra chip disease ( ZC ) is an emerging disease of potato in which tubers are produced with striped necrotic patterns that make them unmarketable . - pubmed
The effect of L - thyroxine substitution on oxidative stress in early - stage diabetic nephropathy patients with subclinical hypothyroidism : a randomized double - blind and placebo - controlled study . - pubmed
PURPOSE : To study oxidative stress status of early type 2 diabetic nephropathy ( DN ) patients with subclinical hypothyroidism ( SCH ) and to assess effect of L - thyroxine therapy on the oxidative stress in these patients . - pubmed
A total of 48 patients with early type 2 DN were included as Euthyroid group , and 92 early type 2 DN with SCH were selected and randomly assigned to L - thyroxine treatment group ( LT4 group ) and placebo group ( SCH group ) . - pubmed
CONCLUSION : Oxidative stress is greater in the DN patients with SCH , and SCH may exacerbate kidney injury in early DN patients . - pubmed
The LT4 treatment may decrease the oxidative stress and attenuate renal injury in DN patient with SCH . - pubmed
Age- and gender - related hemorheological alterations in intestinal ischemia - reperfusion in the rat . - pubmed
Platelet count elevated in the younger male and older female I / R animals . - pubmed
Only standardized parasitological tools , supplemented by epidemiological analysis , will be able to clarify whether parasite carriage could be connected to IBS and its status as a human pathogen . - pubmed
Therapy study was conducted in triple - negative breast cancer - bearing BALB / c mice . - pubmed
Application to Bartonella henselae infection RNAi screening data yielded an eight node network largely in agreement with previous works , and revealed novel binary interactions of direct impact between established components . - pubmed
Most animal models of diabetic retinopathy are hyperglycaemia - only models that do not account for the significant role that inflammation plays in the development of the disease . - pubmed
In the present study , we present data on the establishment of a new animal model of diabetic retinopathy that incorporates both hyperglycaemia and inflammation . - pubmed
Oral treatment with CAW also attenuates hippocampal mitochondrial dysfunction in these animals . - pubmed
BACKGROUND : Besides mammography , breast ultrasound is the most important imaging modality for women with suspected breast cancer . - pubmed
Exposing mice to patient 's refluxates induced expansion of multi - layered glandular structures and development of columnar metaplasia at the squamo - columnar junction . - pubmed
Our findings support the hypothesis that in humans , BE arises from non - squamous cells residing in submucosal gland ducts and that induction of intestinal type of metaplasia is most effectively induced by glycine - conjugated bile acids . - pubmed
Patients with & lt;90 - day follow - up , intraoperative graft preparation with an antibiotic other than vancomycin , or previous ipsilateral knee infection were excluded . - pubmed
Distribution and relevance of Dientamoeba fragilis and Blastocystis species in gastroenteritis : results from a case - control study . - pubmed
The actual role of Dientamoeba fragilis and Blastocystis in patients with gastrointestinal symptoms is still under debate . - pubmed
In the present study , a real - time PCR for Blastocystis was performed on 1374 case samples and 1026 control samples from the multicenter gastroenteritis case - control study previously tested for D. - pubmed
METHODS : Patients with colorectal adenocarcinoma ( ADEC ) , neuroendocrine carcinoma ( NEC ) , MANEC and ANED were identified diagnosis from 2010 to 2014 using the Surveillance , Epidemiology , and End Results ( SEER ) database . - pubmed
Deep inspirations attenuate postprandial airway inflammation in college - aged adults with elevated baseline exhaled nitric oxide : A pilot study . - pubmed
The role of social support on the effects of stress and depression on African American tobacco and alcohol use . - pubmed
West Nile Virus and Related Flavivirus in European Wild Boar ( Sus scrofa ) , Latium Region , Italy : A Retrospective Study . - pubmed
BACKGROUND : A retrospective sero - survey for evidence of West Nile virus ( WNV ) infection in European wild boar ( Sus scorfa ) was conducted in the Latium region , Italy , on stored serum samples of the period November 2011 to January 2012 . - pubmed
Postoperative Adjuvant Transarterial Infusion Chemotherapy with FOLFOX Could Improve Outcomes of Hepatocellular Carcinoma Patients with Microvascular Invasion : A Preliminary Report of a Phase III , Randomized Controlled Clinical Trial . - pubmed
BACKGROUND : Microvascular invasion ( MVI ) is a risk factor for tumor recurrence after hepatectomy in hepatocellular carcinoma ( HCC ) patients . - pubmed
OBJECTIVE : This study aimed to investigate the efficacy and safety of postoperative adjuvant transarterial infusion chemotherapy ( TAI ) with the FOLFOX regimen for HCC patients with MVI . - pubmed
CONCLUSIONS : Adjuvant TAI after hepatectomy may bring survival benefits to HCC patients with MVI . - pubmed
Case : We describe a case of a 62 - year - old female patient admitted with acute ST - elevation myocardial infarction ( STEMI ) treated by primary coronary intervention ( primary PCI ) with a drug - eluting stent placement . - pubmed
Patients and Methods : We measured the following parameters of DDH and contralateral normal hip ( CNH ) of proximal morphology of femurs on 65 patients with unilateral Crowe type IV DDH ( 30 hips with no false acetabulum ( type IVA ) and 35 hips with a false acetabulum ( type IVB ) ) in our hospital between September 2009 and July 2019 on anteroposterior radiographs : the widths of medullary canals at 20 mm above the center of lesser trochanter ( CLT ) , 20 mm below the CLT and the isthmus . - pubmed
Although there are effective nucleoside analogs to treat HSV , VZV , and HCMV disease , herpesvirus infections continue to contribute to significant morbidity and mortality . - pubmed
Treatment of HCMV with GCV requires close monitoring particularly in patients with impaired renal function and there are no approved treatments for congenital HCMV infections . - pubmed
New therapeutic options to control cytomegalovirus reactivation in bone marrow and stem cell transplant patients are needed to improve patient outcome . - pubmed
Working memory ( WM ) is known to be impaired in patients with stroke experiencing unilateral spatial neglect ( USN ) . - pubmed
Fourteen USN first - event stroke patients with right - hemisphere damage were tested in two different WM experiments using long and short retention intervals and an analog response scale . - pubmed
This study aimed to estimate time to recovery and to determine predictors of time to recovery among children aged 6 - 59 months with severe acute malnutrition . - pubmed
An accurate understanding of why zoonoses such as SARS - CoV-2 are emerging at an increased rate , is vital to prevent future pandemics from the approximately 700,000 viruses with zoonotic potential . - pubmed
After 7 years , 80.8 % of the patients at risk had developed nephropathy and 75.7 % had developed neuropathy . - pubmed
The lungs and heart were examined morphologically in 24 persons who had died from cirrhosis of the liver in the edematous - ascitic stage . - pubmed
Secondary - compensatory changes in the contractile function of the myocardium of the right parts of the heart in response to increase of pressure in the pulmonary artery in patients with cirrhosis of the liver were proved to occur . - pubmed
Cytotoxic effects of procaine , lignocaine and bupivacaine were investigated on cultures of Chinese hamster lung fibroblasts . - pubmed
Ultrastructural pathology of peripheral nerves in patients with diabetic neuropathy . - pubmed
Sural nerve lesions in patients with clinically manifest diabetic neuropathy were investigated electron microscopically . - pubmed
Myelinated nerve fibers were reduced in all the diabetic patients . - pubmed
These results indicated that the peripheral nerve lesions in human diabetics were mainly due to metabolic impairment of nerve fibers , accompanying dysmetabolism of Schwann cells and diabetic microangiopathy , and that these changes proceeded independently . - pubmed
Since 1959 , 51 patients underwent open heart surgery for correction of an acute dissecting aneurysm of the ascending aorta . - pubmed
Upon admission , 33 patients were severely hypotensive or in progressive heart failure . - pubmed
Acute aortic insufficiency was found in 24 patients , and hemiplegia or hemiparesis in four . - pubmed
Nine patients died within the early postoperative course from uncontrollable hemorrhage ( four ) , further dissection ( three ) and myocardial infarction ( two ) . - pubmed
Within the first year after surgery , another five patients died from acute aortic dissection ( two ) , pseudomonas infection causing rupture of the proximal graft anastomosis ( one ) and myocardial infarction ( two ) . - pubmed
T - lymphocytes response to Friend virus - induced tumour cell lines in mice of strains congenic at H--2 . - pubmed
This case - control study sought to determine whether protection against clinically significant rotavirus diarrhea in children aged 4 - 35 months correlated with titers of serum neutralizing antibody and , if so , whether this protection was serotype - specific . - pubmed
[ The physiotherapy of patients with lumbar spinal osteochondrosis in the early period after surgical treatment ] . - pubmed
Altogether 130 patients with associated lumbar spinal osteochondrosis and the radicular syndrome were placed under observation after operation in the form of laminectomy and removal of hernia of intervertebral discs . - pubmed
Renal transplantation is regularly successful in infancy and should be considered an integral component of the therapy for any child with chronic renal failure . - pubmed
Renal handling of free sialic acid in normal humans and patients with Salla disease or renal disease . - pubmed
The renal handling of free sialic acid , a negatively charged sugar , was investigated in normal humans and in patients with impaired sialic acid metabolism or impaired renal function . - pubmed
In other patients with different degrees of renal insufficiency , free sialic acid clearance varied directly with creatinine clearance , indicating filtration of this sugar by renal glomeruli . - pubmed
In patients with renal Fanconi syndrome , the urinary excretion of free sialic acid was independent of the severity of the generalized tubular defect , indicating that sialic acid was not reabsorbed by renal tubular cells . - pubmed
In addition , three of eight patients with Salla disease , a storage disorder due to impaired lysosomal transport of free sialic acid , were found to have reduced creatinine clearances , but all Salla disease patients had entirely normal renal tubular function . - pubmed
Effects of salicylate on chondrocytes from osteoarthritic and contralateral knees of dogs with unilateral anterior cruciate ligament transection . - pubmed
However , chondrocytes from the contralateral knees of dogs with unilateral OA were notably resistant to the effects of salicylate . - pubmed
Intraoperative esophageal manometry has not been correlated with early postoperative extended esophageal pH monitoring ( EEpHM ) in children with gastroesophageal reflux . - pubmed
Forty - two patients with a clinical diagnosis of bacterial conjunctivitis were enrolled in a randomized , double - blind trial . - pubmed
A phase I trial of chlorambucil administered in short pulses in patients with advanced malignancies . - pubmed
Thirty patients with advanced cancer were entered in six dose levels : 36 , 48 , 60 , 84 , 108 , and 144 mg / m2 . - pubmed
Central nervous system toxicity was dose limiting , occurring in 5 of 6 patients at 144 mg / m2 . - pubmed
Leukopenia ( 3 patients ) and thrombocytopenia ( 2 patients ) were mild . - pubmed
One patient with colorectal carcinoma had a minor response , and two patients with non - small cell lung cancer had stable disease . - pubmed
Statistical assessment of perceptual CT scan ratings in patients with Alzheimer type dementia . - pubmed
Our case relates to giant cell arteritis presenting as pulmonary artery obstruction in a patient without polymyalgia rheumatica or extensive aortic or proximal great vessel involvement . - pubmed
In 115 patients with chronic lymphocytic leukemia ( CLL ) , grouped according to the staging system as proposed by Rai et al . - pubmed
[ Central nervous system of a 12 mm human embryo with complete cyclops : a case of holoprosencephaly ] . - pubmed
A radiological study of 50 patients with thoracic Scheuermann ' s disease revealed two types of lateral spinal curvature . - pubmed
We studied a 17 - year - old girl with subacute necrotizing encephalomyelopathy ( Leigh syndrome ) . - pubmed
Induction of RNA " tumor " viruses by 5 - iodo-2 '- deoxyuridine in mouse fibroblasts is stimulated 5- to 25 - fold by glucogenic adrenal corticosteroids . - pubmed
Congenital otocephalus in a lamb . - pubmed
[ Homotransplantation of preserved kidney by hypothermia and hyperbaric oxygen in man ] . - pubmed
The effect of hypocapnia on the level of halothane anesthesia in man . - pubmed
Passive transfer between experimental animals of hypersensitivity to Aedes aegypti bites . - pubmed
It is concluded that the reindeer can maintain its body temperature also in severe cold although the extremities show characteristics of heterothermia . - pubmed
Twelve patients with drug resistant ventricular ( 3 ) or supraventricular ( accessory pathway ( 2 ) , atrial flutter ( 3 ) , junctional tachycardia ( 3 ) , supraventricular tachycardia ( 1 ) tachyarrhythmias are reported in whom , after electrophysiological analysis of the individual tachycardia , a specially designed stimulation system was implanted . - pubmed
After pacemaker implantation we observed a significant decrease in incidence and/or duration of tachycardic episodes in all patients . - pubmed
In two patients atrial pacing ( 80 and 90 / min ) suppressed tachycardias completely . - pubmed
These stimulatory effects of SA96 and D - PA on the humoral immune responses were also not dose - dependent , and the maximum effects of SA96 were observed with 10 mg / kg / day , as in the case of adjuvant - induced arthritis in rats . - pubmed
Withdrawal and subsequent reintroduction of EN confirmed that there was worsening of left ventricular dysfunction in the other 3 subjects . - pubmed
At maximal exercise , cardiac and stroke volume indexes increased by 29 and 18 % , respectively ( p less than 0.01 ) , after EN ; the duration of exercise increased in 7 of the 10 subjects after acute therapy and this was maintained on a long - term basis . - pubmed
Amitriptyline in children with major depressive disorder : a double - blind crossover pilot study . - pubmed
Cerebral blood flow and cerebral metabolism in children following cardiac surgery with deep hypothermia and circulatory arrest . - pubmed
Between November 1975 and June 1977 , 49 children underwent repair of complicated cardiac defects with the aid of deep hypothermia . - pubmed
Nine children died ( 18 % ) due to early postoperative heart failure . - pubmed
A decisive cause of death in terms of important cardiovascular defects , which were either unknown or not correctable at the time of repair , was found in 6 patients . - pubmed
Children with complicated forms of congenital heart disease requiring an extensive repair were overrepresented among those who died . - pubmed
Hence , there was an excess in the duration of bypass among nonsurvivors ( p less than 0.01 ) whereas the patient 's age at operation , the use of circulatory arrest and the duration of aortic occlusion had no bearing on operative mortality . - pubmed
min-1 in 3 children with long periods of circulatory arrest . - pubmed
However , in 3 children operated with circulatory arrest , difficulties in performing more delicate motor activities were noted by the parents . - pubmed
[ Determination of the development of psychotic dependence to drugs in small animals . - pubmed
To develop a screening method for psychic dependence liability of the drugs , morphine- and cocaine - directed drinking behavior was studied in mice . - pubmed
When the animals were forcedly given drugs as drinking solution total intake and the gain of body weight was suppressed in proportion to the concentration of the drugs . - pubmed
[ A case of neonatal meningitis caused by group B streptococcus ( S. - pubmed
Hypothalamic obesity in male rats : comparison of parasagittal , coronal , and combined knife cuts . - pubmed
In 124 children , age 6 months to 6 years , suspected to have asthma the non - electrostatic spacer delivered a mean total dose of budesonide aerosol of 39 % of the nominal dose , which was significantly higher than the Babyhaler ( 28 % ) , the Nebuhaler ( 21 % ) , and the AeroChamber ( 19 % ) . - pubmed
Up to 85 % of patients with bronchogenic carcinoma are inoperable at the time of diagnosis and treatment remains largely palliative . - pubmed
Patients with inoperable lung cancer and obstruction of central airways should undergo initial endobronchial therapy followed by conventional chemo - radiotherapy . - pubmed
Functional neuroimaging with positron emission tomography previously demonstrated reduced caudate glucose metabolism in virtually all symptomatic patients with Huntington ' s disease ( HD ) . - pubmed
Single - photon emission computed tomography studies of brain blood flow also have shown caudate abnormalities in patients with HD . - pubmed
The present study compared these two functional imaging modalities in 6 patients with HD who had been symptomatic for fewer than 5 years . - pubmed
The role of this technique in the management of HIV positive patients with empyema is discussed . - pubmed
Appropriateness of serologic tests and parenteral antibiotic therapy for patients with presumed Lyme disease . - pubmed
This 32 - year - old patient with hairy cell leukaemia demonstrated extensive bony involvement in a pattern not previously described . - pubmed
Putative bovine B cell lineage tumor in sporadic bovine leukosis . - pubmed
A tumor cell line , BLC3 , established from calf C924 in nude mice was examined for immunophenotype , DNA rearrangement of immunoglobulin ( Ig ) genes and expression of cellular oncogenes c - abl , c - myc and c - myb . - pubmed
Taken together , our data show that the calf type of SBL found in these two calves is induced by immature pre - B cells , including tumor cell line BLC3 established in nude mice . - pubmed
Renal sonography detected only 6 of 16 patients with pyonephrosis ( specificity 96 % , sensitivity 38 % , accuracy 72.5 % ) . - pubmed
BACKGROUND : In severe human heart failure , an increase in frequency of stimulation is accompanied by a reduced force of contraction in vivo and in vitro . - pubmed
Eight unexpected cardiorespiratory arrests occurred in seven children ( 9 % ) . - pubmed
Chronic congestive heart failure was noted in 10 % of patients . - pubmed
Thirty children died , 10 with significant cardiac dysfunction . - pubmed
Eighteen patients with Paget ' s disease of bone were randomly allocated to three therapeutic groups receiving respectively 600 , 800 , and 1200 mg / day tiludronate for five days . - pubmed
Fifty per cent of patients treated by a dose of 1200 mg / day reported gastrointestinal disturbances , however , making this dosage unsuitable for clinical practice . - pubmed
Liver scintigraphy using 99mTc - GSA was performed on 13 patients with liver disease . - pubmed
Steroid - induced sex determination at incubation temperatures producing mixed sex ratios in a turtle with TSD . - pubmed
Previous studies have shown that exogenous steroid hormones can affect sex determination in reptiles with temperature - dependent sex determination ( TSD ) . - pubmed
Creatinine and urea clearance during continuous veno - venous haemofiltration in critically ill patients . - pubmed
Urea and creatinine clearances achieved using continuous veno - venous haemofiltration were calculated in 16 critically ill patients , during 50 episodes of filtration . - pubmed
A retrospective study of patients hospitalized for treatment of cystic lesions associated with retained third molars during a 10 - year period showed a total of 32 cystic lesions in 25 patients . - pubmed
These data should raise the question related to suprarenal response to acute or prolonged stresses , such as surgical operations or shock in women using Norplant implants . - pubmed
Spindle and motoneuronal contributions to the phase advance of the human stretch reflex and the reduction of tremor . - pubmed
The most common underlying disease was epidermoid carcinoma ( 82 percent ) , the average patient age was 55 years , and the average length of follow - up was 13.5 months . - pubmed
Postoperatively , two patients experienced fracture at the donor site ( 12 percent ) , and three patients ( 18 percent ) had hardware related problems such as exposure , infection , or both . - pubmed
Low - risk human papillomavirus types 6 and 11 associated with carcinomas of the genital and upper aero - digestive tract . - pubmed
BACKGROUND : Human papillomavirus ( HPVs ) types 6 and 11 , are frequently found in non - malignant anogenital condylomas and laryngeal papillomas . - pubmed
RESULTS : Four invasive carcinomas containing HPV 6 or 11 could be detected ( 2.4 % ) by Southern blot technique . - pubmed
HPV 6 DNA was found in a penile carcinoma , a groin carcinoma , and in a tonsillar carcinoma . - pubmed
One cervical carcinoma harbored HPV 11 DNA . - pubmed
Using HPVs 6 , 11 , 16 , 18 and 33 anticontamination primers and probes in PCR , no additional high - risk HPV types could be detected in these four cancers . - pubmed
CONCLUSION : This report shows the presence of low - risk HPVs ( HPV 6 and 11 ) associated to malignant tumors in a frequency higher than usually observed . - pubmed
The data raise questions about which are the circumstances which may favor low - risk HPV related oncogenesis . - pubmed
OBJECTIVE : The Agency for Health Care Policy and Research ( AHCPR ) has recently published guidelines for the management of patients with acute low back pain , which include recommendations for the use of lumbar radiographs , based on the identification of " red flags " for fractures , tumors , or infections . - pubmed
PATIENTS : The records of all patients seen in 1992 and 1993 with a new episode of low back pain were reviewed : 963 patients had a history of back pain of less than 3 months . - pubmed
RATIONALE AND OBJECTIVES : We determined whether a limited number of high - resolution computed tomography ( HRCT ) scans will effectively screen for interstitial lung disease ( ILD ) in a population of individuals exposed to asbestos . - pubmed
PURPOSE : We present our experience with preoperatively administered hyperbaric oxygen therapy to patients who have sustained significant therapeutic radiation induced soft tissue injuries and subsequently undergo planned abdominal intervention / surgery . - pubmed
Internal radiation therapy for patients with primary or metastatic hepatic cancer : a review . - pubmed
BACKGROUND : The limited efficacy of current approaches to the treatment of patients with hepatic cancer , including external beam radiation therapy and cytotoxic chemotherapy , has reawakened interest in the use of internal radiation therapy . - pubmed
METHODS : The authors reviewed series of patients with liver metastases or hepatocellular carcinoma ( HCC ) treated with 1 ) interstitial irradiation and direct intratumoral injection of 90Y microspheres , 2 ) intraarterial infusion of ( 131 ) I - Lipiodol , 3 ) intraarterial infusion of 90Y microspheres , or 4 ) parenteral administration of radiolabeled monoclonal antibodies . - pubmed
RESULTS : High dose rate interstitial irradiation with afterloading of ( 192 ) Ir resulted in local control of hepatic metastases for a median of 8 months and complete tumor eradication in 2 patients . - pubmed
Direct intratumoral injection of 90Y microspheres reduced the size of 90.6 % of tumors and completely destroyed them in 8 patients . - pubmed
Partial response was commonly achieved when patients with unresectable liver metastases or HCC were treated with intraarterial 9OY microspheres . - pubmed
Among four patients whose HCC became resectable following treatment with 90Y microspheres , two cases of complete remission were documented . - pubmed
and Anopheles funestus rank among the world 's most efficient vectors of human malaria . - pubmed
DESIGN : Case report of a 64 - year - old man who developed weakness and numbness of the distal legs after an operation for mesenteric thrombosis . - pubmed
[ T lymphocyte immunological response to different antigenic fractions of Mycobacterium bovis in juvenile chronic polyarthritis ] . - pubmed
RESULTS : Patients with juvenile chronic polyarthritis had a intense reaction against 65 kDa fraction and a second fraction located between 32.5 and 27.5 kDa . - pubmed
Sperm retrieval and intracytoplasmic sperm injection in patients with prune - belly syndrome . - pubmed
In humans , IGF-1 improves cardiac function after myocardial infarction by stimulating contractility and promoting tissue remodeling . - pubmed
Treatment of patients with Paget ' s disease of bone . - pubmed
OBJECTIVE : The role of surgery in the treatment of patients with pulmonary and hepatic metastases from colorectal cancer has not been delineated . - pubmed
METHODS : Of the 351 patients enrolled in the Metastatic Lung Tumor Study Group of Japan between June 1988 and June 1996 who underwent thoracotomy for pulmonary metastases from colorectal cancer , 47 also underwent hepatic resection for metastatic tumors . - pubmed
This patient was alive without recurrence . - pubmed
There was a significant difference in the cumulative survival of the patients with a solitary pulmonary metastasis and the patients with multiple pulmonary metastases ( P = .04 ) . - pubmed
However , 9 of 10 patients who survived 3 years or more after the initial thoracotomy had only one or two hepatic metastases . - pubmed
Patients with a solitary pulmonary metastasis and a small number of hepatic metastases are good candidates for resection . - pubmed
In a genome - wide screening of the MRL background genes mediating susceptibility to collagen diseases using N2 progeny mice MRL / lpr x ( MRL / lpr x C3H / lpr ) F1 , we previously found that each collagen disease is controlled by a different set of genes . - pubmed
From their composition these loci seemed to be derived from AKR / J ( for one ) and LG / J ( for another two ) strains , and appeared to act in an additive manner on the development of vasculitis , indicating that vasculitis in MRL / lpr mice is inherited in a polygenic manner . - pubmed
Two patients had a non - Q myocardial infarction . - pubmed
Prion diseases have aroused particular interest ever since the appearance of BSE ( mad cow disease ) , a prion disease of cattle that can apparently be transmitted to humans and which is the cause of a new variant of Creutzfeldt - Jakob disease . - pubmed
Fertilization , development , and chromosomal status of the embryos were compared with a control group ( n = 18 ) of patients undergoing preimplantation genetic diagnosis for sex chromosome - linked diseases . - pubmed
OBJECTIVE : To assess the potential for the development of aluminum toxicity in patients with renal insufficiency or chronic renal failure who are taking sucralfate . - pubmed
Accumulation of aluminum in patients with impaired renal function may lead to significant toxicity . - pubmed
Studies and case reports evaluating the use and toxicity of sucralfate in patients with normal renal function , as well as those with renal failure or renal insufficiency , were reviewed . - pubmed
CONCLUSIONS : Aluminum accumulation and toxicity have been reported with the use of sucralfate in patients with compromised renal function . - pubmed
The risk of toxicity most likely represents a long - term complication of sucralfate use in this patient population . - pubmed
These medications , in addition to sucralfate , should be avoided if possible in patients with end - stage renal disease . - pubmed
Patients with renal failure or renal insufficiency who are undergoing prolonged sucralfate therapy should be monitored for potential signs of aluminum toxicity . - pubmed
[ Intravenous and enteral nutrition for the patient with cerebrovascular disease ] . - pubmed
The Syrian golden hamster strain LPN : a useful animal model for human cholelithiasis . - pubmed
The purpose of this study was to specify the main mechanisms at the origin of gallstone formation in very young ( 5 - week old ) or young adult ( 9 - week old ) LPN hamsters fed a sucrose - rich ( normal lipid ) lithogenic diet for one and four weeks , respectively . - pubmed
It was also to compare these mechanisms in the two strains of hamsters ( LPN and Janvier ) or when an anti - lithiasic diet was given by substituting 10 % of the sucrose by beta cyclodextrin . - pubmed
The LPN strain of hamsters showed a very high incidence of cholesterol gallstones ( 73 % ) after receiving the lithogenic diet . - pubmed
The gallstone formation is very rapid and occurs in less than one week in very young hamsters which show a high cholesterol synthesis rate in the liver . - pubmed
An overall comparison of the data obtained in LPN Hamsters and in Man suggests that this hamster strain appears to be an interesting model for human cholelithiasis . - pubmed
[ Secondary biliary cirrhosis in a patient with histiocytosis X ] . - pubmed
The authors present the clinical case of a 62 - year - old female patient , hospitalized for chronic cholestasis , diabetes and gallstone in the main bile duct . - pubmed
Genetic targeting and/or pharmacologic blockade of the implicated pathways may be a future strategy for therapeutic adjunctive measures to improve outcome and may hold substantial promise , in concert with antimicrobial agents , in humans with acute bacterial meningitis . - pubmed
In this study , 39 patients with PD and 25 control subjects without neurologic disease completed testing in a driving simulator . - pubmed
PD patients had more total collisions on the driving simulator than control subjects ( t = -3.7 , p < 0.01 ) . - pubmed
RESULTS : Among children , hepatitis A virus was the major etiologic agent ( 81.6 % in Group A and 51.4 % in Group B ) , followed by hepatitis E virus ( 12.2 % , 46.4 % ) and hepatitis B virus ( 5.4 % , none ) . - pubmed
Among adults , hepatitis E virus was the main causative agent ( 42.4 % in Group A and 71.2 % in Group B ) followed by HBV ( 28 % , 25.5 % ) and hepatitis A virus ( 10.6 % , 3.5 % ) . - pubmed
Cryptosporidium parvum , a protozoan parasite , has been implicated in a number of waterborne disease outbreaks and is difficult to inactivate using free chlorine . - pubmed
The type strain is strain 29W ( T ) (= JCM 11663(T ) = DSM 15103(T ) ) . - pubmed
[ Effect of catechol amines on oxygen consumption in hypercapnia in dogs ] . - pubmed
Mood induction with facial expressions of emotion in patients with generalized anxiety disorder . - pubmed
Patients with general anxiety disorder ( GAD ) , anxiety prone subjects , and normal controls ( n=30 , N=90 ) were subjected to happy and sad mood induction conditions using facial expressions of emotion of varied intensity . - pubmed
A phase I and pharmacokinetic study of irinotecan in patients with hepatic or renal dysfunction or with prior pelvic radiation : CALGB 9863 . - pubmed
BACKGROUND : To ascertain if hepatic or renal dysfunction or prior pelvic radiation ( XRT ) leads to increased toxicity at a given dose of irinotecan and to characterize the pharmacokinetics of irinotecan and its major metabolites in patients with hepatic or renal dysfunction . - pubmed
PATIENTS AND METHODS : Adults with tumors appropriate for irinotecan therapy and who had abnormal liver or renal function tests or had prior radiation to the pelvis were eligible . - pubmed
RESULTS : Thirty - five patients were evaluable for toxicity . - pubmed
No dose - limiting toxicity was seen in cohort I , although only three patients were treated and at a dose of 225 mg / m(2 ) . - pubmed
Patients with elevations of direct bilirubin had dose - limiting toxicities , even though the starting dose was 145 mg / m(2 ) . - pubmed
Patients with elevations of creatinine or with prior pelvic radiotherapy did not appear to have increased risk of toxicity at the doses explored in this study . - pubmed
CONCLUSIONS : Patients with elevated bilirubin treated with irinotecan have an increased risk of toxicity and a dose reduction is recommended . - pubmed
Herbal preparations derived from black walnut have been used as hair dyes and skin colorants in addition to being applied topically for the treatment of acne , inflammatory diseases , ringworm , and fungal , bacterial , or viral infections . - pubmed
METHODS : Twenty patients with verrucous epidermal nevi were treated with Er : YAG laser . - pubmed
RESULTS : After a single laser treatment , successful elimination of the verrucous epidermal nevi was observed in 15 patients . - pubmed
Five patients ( 25 % ) showed a relapse within 1 year after the treatment . - pubmed
Erythema occurred in all patients after the laser treatment and subsided in 2 months . - pubmed
Postinflammatory hyperpigmentation occurred in two patients ( 10 % ) . - pubmed
One patient ( 5 % ) experienced transient hypopigmentation . - pubmed
Mild to moderate postoperative acne flare - up occurred in one patient ( 5 % ) with facial lesions . - pubmed
INTRODUCTION : In a follow - up examination 50 patients who had sustained dorsal dislocations of the proximal interphalangeal ( PIP ) joint , the results of two conservative therapy regimens , either immobilisation or early motion , were investigated . - pubmed
The inclusion criteria were : adult patients over the age of 18 with isolated , acute , closed dorsolateral dislocation of the PIP joint . - pubmed
Two patients complained of a limitation of extension , 3 of limitation of extension and pain , and 1 of pain and swelling . - pubmed
Palmar instability did not occur , and 18 patients were satisfied . - pubmed
One patient complained of instability , pain and lack of extension during hard work , 1 of pain in combination with instability , 2 of pain and 3 of swelling of the joint . - pubmed
Proof of the mysterious efficacy of ginseng : basic and clinical trials : effects of red ginseng on learning and memory deficits in an animal model of amnesia . - pubmed
Ameliorating effects of red ginseng on learning and memory deficits due to hippocampal lesions and aging were reviewed ; the performance of young rats with selective hippocampal lesions with or without red ginseng ( p.o . ) - pubmed
The results in the DMT and RRPST indicated that motivational and motor activity of young rats with hippocampal lesions with and without ginseng and aged rats with and without ginseng were not significantly different from that of control young rats . - pubmed
However , young rats with hippocampal lesions without ginseng and aged rats without ginseng displayed significant deficits in the PLT . - pubmed
Treatment with red ginseng significantly ameliorated place - navigation deficits in young rats with hippocampal lesions in the PLT . - pubmed
The results , along with previous studies showing significant effects of red ginseng on the central nervous system , suggest that red ginseng ameliorates learning and memory deficits through effects on the central nervous system , partly through effects on the hippocampal formation . - pubmed
These improved immunophenotypic definitions of macaque NK cells should facilitate future analysis of innate immune responses in rhesus macaques and the role of NK cells in AIDS pathogenesis in Simian immunodeficiency virus ( SIV )- infected macaques . - pubmed
Importantly though , the product appears to be relatively free of antigenicity , thrombogenicity and risk of viral transmission that , in the past , have limited the utility of blood products . - pubmed
METHODS : We analyzed data for all pregnant women admitted to the hospital in Canada over 7 years to test whether major trauma still clustered in the summer despite their aversion toward alcohol , recklessness , and extreme sports . - pubmed
The 133 women included were divided into two groups : ( 1 ) Non - brachial plexus injury ( Non - BPI ) group : 106 women with labours complicated by shoulder dystocia . - pubmed
BACKGROUND : Little is known about the neuropsychological status of youth with bipolar disorder ( BPD ) or whether cognitive deficits in this population are accounted for by comorbidity with attention deficit / hyperactivity disorder ( ADHD ) . - pubmed
We compared neuropsychological and academic functioning of youth with and without DSM - IV BPD , controlling for effects of comorbid ADHD . - pubmed
METHODS : Fifty - seven youth with BPD and 46 healthy control subjects were assessed on a battery of clinical neuropsychological measures including subtests from the Wechsler Intelligence Scales for Children and Adults ( Third Editions ) , the Stroop , the Wisconsin Card Sorting Test , the Rey - Osterreith Complex Figure , an auditory working memory Continuous Performance Test , a measure of verbal learning , and the Wide Range Achievement Test - Third Edition . - pubmed
This metaregression analysis examines the relationship between several surrogate markers and survival in women with advanced breast cancer after receiving first - line combination anthracycline chemotherapy 5 - fluorouracil , adriamycin and cyclophosphamide ( FAC ) or 5 - fluorouracil , epirubicin and cyclophosphamide ( FEC ) . - pubmed
PURPOSE : To validate the accuracy of ventricular function analysis using a single breath - hold real - time steady sate free precession ( SSFP ) cine MR method and demonstrate its application during adenosine stress imaging in children with congenital heart disease . - pubmed
CONCLUSION : Single breath - hold real - time SSFP cine imaging is robust and accurate in assessing cardiac function in children with congenital heart disease . - pubmed
Two other clusters , joined at a similarity of 53 % , included reference strains of Bradyrhizobium elkanii , but not USDA 76 T ; furthermore , two other major clusters were identified and all strains were clustered at a final level of similarity of only 28 % . - pubmed
Reference strains of B. - pubmed
japonicum fell into a major group with 51 strains , 84 % isolated from soybean , with a similarity of 59 % , while strains of B. - pubmed
In a combined analysis with the three ribosomal regions , the majority of strains isolated from soybean clustered with a similarity of 54 % with type and reference strains of B. - pubmed
japonicum , while most strains isolated from Brazilian indigenous legume species grouped with B. - pubmed
OBJECTIVE : Activated synoviocytes play important roles in the progression of human osteoarthritis ( OA ) . - pubmed
METHOD : Synovial fluid - derived FLS were obtained from the knees of 15 patients with early stage OA . - pubmed
METHODS : In this study , both - ends - threaded locking screws were used to treat 68 tibial fractures , including 56 acute fractures in 54 patients and 12 nonunions in 12 patients . - pubmed
Three patients underwent exchange nailing and bone grafting and had eventual fracture union . - pubmed
Recovery of joint motion was essentially normal in patients without knee or ankle injury . - pubmed
Three patients died of their disease ( 17.6 % ) , 2 patients died from unrelated reasons , 1 patient was lost to follow - up , and the other 12 patients are alive with no evidence of disease . - pubmed
CASE REPORT : We report on a woman patient in whom craniocerebral trauma involved a fracture of the left optic canal with unilateral loss of vision . - pubmed
RESULTS : Occult DCM was diagnosed in 21 dogs . - pubmed
Additional studies should be performed to optimize this method of screening dogs to detect occult DCM . - pubmed
Differential impact of heavy cannabis use on sensory gating in schizophrenic patients and otherwise healthy controls . - pubmed
cannabis controls ; n=11 ) and compared it to that of schizophrenic patients ( n=12 ) and healthy controls ( n=18 ) without cannabis or other drug abuse . - pubmed
RESULTS : A total of 561 polyps in 486 patients were resected by endoscopic polypectomy . - pubmed
Overall , bleeding complications occurred in 7.6 % ( 37/486 ) of the patients , including 4.9 % ( 12/244 ) in the epinephrine group , and 10.3 % ( 25/242 ) in the saline group . - pubmed
Early and late postpolypectomy bleeding ( PPB ) occurred in 6.6 % ( 32/486 ) and 1 % ( 5/486 ) of the patients , respectively , including 4.5 % ( 11/244 ) , 0.4 % ( 1/244 ) in the epinephrine group , and 8.7 % ( 21/242 ) , 1.7 % ( 4/242 ) in the saline group . - pubmed
Spatial patterns of brain atrophy in MCI patients , identified via high - dimensional pattern classification , predict subsequent cognitive decline . - pubmed
Approximately 2/3 of the MCI group presented patterns of atrophy that overlapped with AD , whereas the remaining 1/3 overlapped with cognitively normal individuals , thereby indicating that some , but not all , MCI patients have significant and extensive brain atrophy in this cohort of MCI patients . - pubmed
Rats were implanted with 9L gliosarcomas and the tumors were diagnosed by MRI . - pubmed
Muscle tenderness is an important complex trait for meat quality and thus for genetic improvement through animal breeding . - pubmed
Muscle ( longissimus dorsi ) samples from 30 F(2 ) pigs were characterized by Warner - Bratzler Shear Force ( WBSF ) on cooked meat as a measurement of muscle tenderness . - pubmed
It has been shown that elderly patients with dementia treated with atypical and conventional antipsychotics have a twofold increased risk of cerebrovascular adverse events ( CVAEs ) . - pubmed
The risk of CVAE in elderly patients associated with antipsychotics is elevated especially during the first weeks of treatment . - pubmed
Large variability of aripiprazole and dehydroaripiprazole serum concentrations in adolescent patients with schizophrenia . - pubmed
In 33 consecutively admitted patients of a child and adolescent psychiatric hospital [ age ( mean + /- standard deviation ) 18.7 + /- 1.7 years ( range , 13.5 - 21.6 years ) ] , 117 steady - state serum concentrations ( repeated samples from individuals ) of aripiprazole and its metabolite dehydroaripiprazole were assessed using high - performance liquid chromatography . - pubmed
Resveratrol , present in grapes and red wine , is reported to be a natural chemopreventive agent against cancer . - pubmed
Recent advances in our understanding of basic biological processes have resulted in the opening of new avenues for treatment of human genetic diseases , especially single gene disorders . - pubmed
A significant proportion of human genetic disorders have been shown to be caused due to degradation of transcripts for specific genes through a process called nonsense mediated decay ( NMD ) . - pubmed
METHOD : All patients referred for the treatment of haemorrhoids over a period of 5 years were prospectively included in a database . - pubmed
In contrast , TB control remains poor in many developing countries , especially those worst affected by poverty and the human immunodeficiency virus ( HIV ) epidemic . - pubmed
Novel real - time PCR assay for simultaneous detection and differentiation of Clostridium chauvoei and Clostridium septicum in clostridial myonecrosis . - pubmed
In this study we used FreeSurfer , a freely - available and automated software tool , to measure cortical thickness in 28 pathologically - confirmed AD patients , of which 11 had a typical amnestic presentation and 17 an atypical presentation during life , 23 pathologically - confirmed FTLD subjects , and 25 healthy controls . - pubmed
In contrast , lower cortical thickness in the anterior temporal lobe and frontal lobe is indicative of the presence of FTLD pathology in patients with a clinical presentation of FTD . - pubmed
Reduced cortical thickness in the posterior cingulate gyrus is characteristic of AD pathology in patients with typical and atypical clinical presentations of AD , and may assist a clinical distinction of AD pathology from FTLD pathology . - pubmed
Therefore , we hypothesized that PD patients would have difficulty switching from one saccade response to the other , with particular impairment in switching from a pro to an antisaccade . - pubmed
Effects of combination dobutamine and vasopressin therapy on microcirculatory blood flow in a porcine model of severe endotoxic shock . - pubmed
In a phase III trial ( the UK ABC-02 trial ) conducted by the American Society of Clinical Oncology ( ASCO ) in 2009 , in which gemcitabine + CDDP combination therapy was compared against gemcitabine monotherapy to treat patients with advanced or metastatic biliary tract cancers , the overall duration of survival was significantly prolonged and the mortality risk reduced . - pubmed
We retrospectively reviewed the medical records of 28 patients with oropharyngeal cancer , who were treated with immediate reconstruction with an ALT free flap after excision . - pubmed
Most of the patients had T3 - 4 tumours and involved neck nodes . - pubmed
coli ( UPEC ) from countries with high infection burden , such as India , hinders the infection control and management efforts . - pubmed
coli isolates from India as well as 50 ExPEC strains from Germany . - pubmed
Our aim was to combine the use of the hen animal model and microarray technology to identify differentially expressed genes in ovarian tissue from normal hens compared with hens with ovarian cancer . - pubmed
We found that the transcripts up - regulated in chicken ovarian tumors were enriched for oviduct - related genes . - pubmed
In addition , one of the oviduct - related genes identified in our analysis , paired box 2 has been implicated in human ovarian cancer and may serve as a marker of the disease . - pubmed
The expression of oviduct - related genes in early - stage tumors is similar to what is seen in human ovarian cancer , with tumors resembling normal Mullerian epithelium . - pubmed
These data suggest that chicken ovarian tumors may arise from alternative sites , including the oviduct . - pubmed
The mean age was 6.9 months ( SD 5.7 ) ; the mean number of days between skeletal surveys was 18.7 ( SD 10.1)Four children ( 8.5 % ) had signs of healing bone trauma on a follow - up skeletal survey . - pubmed
A series of beta - carboline derivatives bearing a substituted - carbohydrazide moiety at C-3 were synthesized and evaluated for their antitumor activity against eight human cancer cell lines . - pubmed
Rituximab induces resolution of recurrent diffuse alveolar hemorrhage in a patient with primary antiphospholipid antibody syndrome . - pubmed
We describe a patient with primary APS and refractory recurrent episodes of DAH . - pubmed
The patient was admitted 15 times due to recurrent episodes of DAH in a period of 18 months . - pubmed
In a follow - up of more than 2 years after he received rituximab , the patient has had no further admissions due to DAH . - pubmed
We assessed the use of FRET - based substrates in an assay to distinguish breast cancer patients from controls . - pubmed
Oseltamivir is recommended by the World Health Organization ( WHO ) for use in the clinical management of pandemic and seasonal influenza of varying severity , and as the primary antiviral agent for treatment of avian H5N1 influenza infection in humans . - pubmed
The analysis of possible morphogenesis of the different structures in human yolk sac tumor has been considered . - pubmed
Transcatheter closure of a residual patent ductus arteriosus after surgical ligation in children . - pubmed
SUBJECTS AND METHODS : Between June 2005 and December 2009 , transcatheter occlusion of residual postsurgical ductus arteriosus was performed in six children . - pubmed
We retrospectively reviewed the electroencephalography laboratory database and paediatric neurology clinic records ( from January 2000 to June 2009 ) at our institution in order to identify patients with absence seizures beginning before age three . - pubmed
Seven of 12 patients had normal neurodevelopment and five had speech delay . - pubmed
Four patients were seizure - free without AEDs , three were seizure - free with a single AED , and five still had seizures with multiple AEDs . - pubmed
Three patients had recurrences after medication withdrawal . - pubmed
Other previously published series have identified better seizure control than that reported here , however , 16 % of the 130 patients so far documented are reported to have poorly controlled epilepsy , indicating that early - onset CAE is not a homogeneous condition . - pubmed
Emerging evidence on rehabilitative interventions and advancements in concomitant surgeries , including those addressing chondral and meniscal injuries , continues to grow and greatly affect the rehabilitative care of patients with anterior cruciate ligament reconstruction . - pubmed
Death occurred in 28 patients over a median follow - up of 3.2 years . - pubmed
METHODS : Children aged 6 to 13 years old who received a diagnosis of PS in our previous community - based OSA prevalence study were invited to undergo repeat polysomnography ( PSG ) at 4 - year follow - up . - pubmed
CONCLUSIONS : More than one - third of school - aged children with PS progressed to OSA over a 4 - year period , although only 7.1 % developed moderate to severe disease . - pubmed
RESULTS : A total of 25 children and 15 adults with spina bifida were studied . - pubmed
Cone survival and preservation of visual acuity in an animal model of retinal degeneration . - pubmed
To this purpose , we compared rod and cone viabilities by both ex vivo and in vivo determinations in the rd10 mutant mouse , a validated model of human retinitis pigmentosa . - pubmed
The results of biochemical , morphological and functional assays converged to show that , in treated rd10 mice cone photoreceptors , the inner retina and overall visual performance were preserved well after rod death . - pubmed
Effects of cabergoline on hyperprolactinemia , psychopathology , and sexual functioning in schizophrenic patients . - pubmed
Our data suggest that cabergoline administration to clinically stable patients with schizophrenia may improve sexual functioning without adversely affecting their psychopathologic status , provided that the dose has been suited to the severity of the hyperprolactinemia . - pubmed
BACKGROUND : Depression is the most common psychiatric manifestation in patients with Parkinson ' s disease ( PD ) . - pubmed
The prevalence of recurrent headache was 30.1 % ( 620/2057 ) , girls 35.1 % , boys 25.2 % . - pubmed
The emergence of multidrug - resistant strains of Neisseria gonorrhoeae constitutes a serious threat to public health and necessitates the discovery of new types of antimicrobial agents . - pubmed
We describe three clinical cases of adolescents presenting to an eating disorders program with primary complaints of gastrointestinal symptoms , food avoidance , and associated weight loss . - pubmed
METHODS : Patients who underwent laparoscopic umbilical hernia repair were separated by method of mesh fixation : sutures versus primarily tacks . - pubmed
Additionally , a telephone interview was conducted to assess postoperative pain , recovery time , and overall patient satisfaction . - pubmed
Hernia recurrence occurred in 3 and 2 patients in the sutures and tacks groups , respectively ( P was not significant ) . - pubmed
Diabetes patients are at high risk for development of cardiovascular disease . - pubmed
From current data , alogliptin and saxagliptin do not change cardiovascular risk in type 2 diabetes mellitus ( T2DM ) patients . - pubmed
Vildagliptin does not alter myocardial function in T2DM patients with systolic dysfunction . - pubmed
However , the possibility of an increase in clinical heart failure and worsened outcomes in patients with existing heart failure is suggested by current data . - pubmed
RESULTS : Repetitive challenge divided the monkeys into two groups with respect to their susceptibility to infection : highly susceptible ( 2 - 3 challenges , 5 monkeys ) and poorly susceptible ( & gt;=6 challenges , 3 monkeys ) . - pubmed
Differences in persistency with teriparatide in patients with osteoporosis according to gender and health care provider . - pubmed
UNLABELLED : This analysis investigated the persistence of teriparatide for treatment of osteoporosis in 829 patients according to gender and health care provider treated with teriparatide . - pubmed
We found a highly significant decreased risk for treatment discontinuation in patients with fractures prior to treatment initiation compared to those without such fractures ( hazard ratio ( HR ) 0.77 ; 95 % confidence interval ( CI ) 0.66 - 0.90 ) . - pubmed
TPTD persistence in patients with osteoporosis is higher than with antiresorptives but is still suboptimal and needs to be improved to ensure fracture risk reductions comparable to randomized controlled trial ( RCT ) results . - pubmed
The aim of the work is to discuss on isolated single coronary artery in two adults presenting as acute coronary syndrome . - pubmed
Having been prescribed Mu Tong that was adulterated with Guan Mu Tong ( Aristolochia manshuriensis ) before 2004 , or an estimated consumption of more than 1 - 100 mg of aristolochic acid , were both associated with an increased risk of UC in the multivariable analyses . - pubmed
METHODS AND RESULTS : We studied a total of 74 human coronary plaque specimens obtained at autopsy . - pubmed
Evaluation of safety and efficacy of intravenous zanamivir in the treatment of hospitalized Japanese patients with influenza : an open - label , single - arm study . - pubmed
There is an unmet need for a parenteral influenza antiviral therapy to treat hospitalized patients . - pubmed
Therefore the safety and efficacy profile of intravenous zanamivir ( IVZ ) was examined in Japanese patients with severe influenza . - pubmed
Patients hospitalized with influenza were treated with IVZ 600 mg twice daily for five days . - pubmed
CONCLUSIONS : In this study there were no new significant safety findings or patterns of AEs related to IVZ and therefore the safety profile was confirmed for a small sample of Japanese hospitalized patients with influenza . - pubmed
This strategy may lead to significant tumor regression , ultimately leading to a complete pathologic response in up to 42 % of patients . - pubmed
INTRODUCTION : Dermoids of the Eustachian tube are rare benign developmental tumours that typically occur in female children . - pubmed
This approach could be used also in new - born children , decreasing the morbidity of the classic surgical treatment and avoiding the risk of craniofacial alterations . - pubmed
HIV / AIDS and family planning services integration : review of prospects for a comprehensive approach in sub - Saharan Africa . - pubmed
However , the integration of family planning into HIV / AIDS programmes , or vice versa , would permit women of reproductive age who are infected or affected by HIV to benefit from family planning and/or HIV - prevention counselling and services . - pubmed
Is Immediate Radical Cystectomy Necessary for All Patients with Non - Muscle - Invasive Micropapillary Bladder Cancer ? - pubmed
The hypothesis is that non - muscle - invasive ( NMI ) MPUC may have a heterogeneous prognosis , and detailed pathological analysis may identify patients that could be managed without immediate cystectomy . - pubmed
PATIENTS AND METHODS : This is a retrospective analysis of patients presenting with MPUC in a primary transurethral resection specimen ( n = 40 ) . - pubmed
[ Successful Hematopoietic Cell Transplantation Following Azacitidine Treatment in an Acute Myeloid Leukemia Patient with t(3;3)(q21;q26.2 ) Translocation and Marked Thrombocythemia ] . - pubmed
A 39 - year - old man visited our department complaining of general malaise and appetite loss . - pubmed
Since the patient 's disease had progressed to acute myeloid leukemia ( AML ) with an increase in the peripheral blast count , he was diagnosed with AML along with t(3;3 ) ( q21;q26.2 ) through a bone marrow aspiration sample . - pubmed
Moreover , recent advancements in our ability to diagnose cMPN have paralleled the development of large clinical trials for patients with cMPN . - pubmed
This article provides explanatory information from these large clinical trials that is useful for the actual clinical practice of caring for patients with cMPN in Japan . - pubmed
METHODS AND RESULTS : We report a cavernous hemangioma extruding from the internal auditory canal , diagnosed after a left translabyrinthine resection in a 45 - year - old man complaining of profound sensorineural hearing loss , with no facial paresis or dizziness . - pubmed
PURPOSE : The choice of distal fusion level in adolescent idiopathic scoliosis ( AIS ) patients with major thoracolumbar or lumbar ( TL / L ) curves ( Lenke type 3C , 5C , or 6C ) remains debatable . - pubmed
Persistent infection by Staphylococcus epidermidis in endodontic flare - up : a case report . - pubmed
A 47 - year - old man reported pain on percussion after uncomplicated retreatment of the maxillary left canine for prosthetic purposes . - pubmed
Five castrated lambs with initial body weights of 36.8 + -3.3 kg , distributed in a Latin square ( 5x5 ) design , were used . - pubmed
CONCLUSIONS : Advances in diagnostic and therapeutic techniques , including surgical cytoreductive techniques , have demonstrated significant survival gains in patients with peritoneal disease . - pubmed
Role of the Common Fragile Sites in Cancers with a Human Papillomavirus Etiology . - pubmed
High - risk human papillomaviruses ( HPVs ) are known to be associated with different anogenital cancers including cervical , anal , penile , and vaginal cancers . - pubmed
The model for how high - risk HPVs induce cancer formation comes from studies of cervical cancer which usually involves integration of the HPV into the human genome and subsequent changes due to induced chromosomal instability . - pubmed
In addition , we summarize studies now done in OPSCC which demonstrate that the role of HPV in these cancers may be different from that in cervical cancer . - pubmed
Finally , we propose new models for how HPV may be involved in the formation of these 2 cancers . - pubmed
Older people aged equal or over 60 without any psychiatric diagnosis were enrolled as healthy controls . - pubmed
OBJECTIVE : To evaluate the feasibility and outcomes of patients operated on for uncomplicated acute appendicitis ( UAA ) in our 24 - h emergency outpatient surgery unit . - pubmed
The median length of hospital stay was 13 h. Postoperative complications were observed in six patients ( 6 % ) . - pubmed
For about 30 years , soon after the onset of the AIDS epidemic , sexual - health messaging has emphasized personal responsibility for using condoms to protect from acquiring or transmitting HIV or other sexually transmitted infections . - pubmed
RESULTS : In the training cohort , median follow - up was 3.0 years ( range , 0.43 - 6.56 years ) and relapse occurred in 36 % of patients . - pubmed
RESULTS AND CONCLUSIONS : In both human and animal studies , neuropathic pain has been associated with a pro - inflammatory state . - pubmed
Forty - five patients ( 2.2 % ) had a postoperative complication , and 74 ( 3.7 % ) patients were readmitted to the hospital after discharge . - pubmed
Lung clearance index ( LCI ) is a marker of ventilation inhomogeneity that is raised in some but not all patients with PCD . - pubmed
We hypothesised that PCD patients with microtubular defects would have worse ( higher ) LCI than other PCD patients . - pubmed
METHODS : Spirometry and LCI were measured in 69 stable patients with PCD . - pubmed
RESULTS : Of the 135 patients who underwent surgery for IPMN , 50 ( 37.0 % ) had low / intermediate - grade dysplasia , 25 ( 18.5 % ) had high - grade dysplasia , and the remaining 60 ( 44.5 % ) had invasive carcinoma . - pubmed
We present a clinical case of a 47 - year - old asymptomatic woman with symptomatic bladder leiomyoma . - pubmed
BACKGROUND : Hyperlactataemia ( HL ) is a biomarker of disease severity that predicts mortality in patients with sepsis and malaria . - pubmed
RESULTS : Of 3170 children in the FEAST trial , including 1719 children ( 57 % ) with Plasmodium falciparum malaria , 3008 ( 95 % ) had a baseline lactate measurement , 2127 ( 71 % ) had HL ( lactate & gt;= 2.5 mmol / L ) , and 1179 ( 39 % ) had severe HL ( & gt;= 5 mmol / L ) . - pubmed
SELECTION CRITERIA : We included published or unpublished randomised controlled trials ( RCTs ) that enrolled adults with venous leg ulcers and compared the effects of at least one of the following interventions with any other intervention in the treatment of venous leg ulcers : any dressing , or any topical agent applied directly to an open venous leg ulcer and left in situ . - pubmed
Clinical characteristics and type of antithrombotic treatment in a Spanish cohort of elderly patients with atrial fibrillation according to dependency , frailty and cognitive impairment . - pubmed
Background : Available data regarding clinical profile and management of elderly patients with atrial fibrillation ( AF ) according to dependency , fragility and cognitive impairment are scarce . - pubmed
The objective of the study was to analyze the biodemographic data , clinical profile and antithrombotic treatment according to dependency , fragility and cognitive impairment in elderly AF patients . - pubmed
Methods : Cross - sectional and multi - center study performed in consecutive AF patients & gt;= 75 years treated with oral anticoagulants & gt;= 3 months attended in Internal Medicine Departments in Spain . - pubmed
This distribution was independent of the presence of dependency or fragility , but there was a trend to a higher prescription of vitamin K antagonists in those patients with cognitive impairment ( 75.2 % vs. 68.8 % ; P = 0.05 ) . - pubmed
Conclusions : Approximately 32%-44 % of elderly anticoagulated AF patients attended have some degree of dependency , fragility and/or cognitive impairment . - pubmed
Approximately 71 % of patients are taking vitamin K antagonists , regardless dependency or frailty , but with a trend to higher prescription in patients with cognitive impairment . - pubmed
Surgical resection represents the standard therapy for patients with colorectal liver metastases ( CRLM ) . - pubmed
Legiolert is a new culture method for quantification of Legionella pneumophila , which is the primary species associated with Legionnaires ' disease . - pubmed
Nail dermoscopy ( onychoscopy ) is useful in diagnosis and treatment follow - up of the nail mixed infection caused by Pseudomonas aeruginosa and Candida albicans . - pubmed
Combined carbon dioxide laser and cryosurgical ablation of rostral nasal septum squamous cell carcinoma in 10 dogs . - pubmed
OBJECTIVES : The study aim was to evaluate the efficacy of combination carbon dioxide ( CO2 ) laser surgery and cryosurgery as a palliative treatment modality in dogs with nasal SCCs . - pubmed
ANIMALS : Ten client - owned dogs with nasal SCC were included : seven neutered males , two spayed females and one intact male , with a median age of 12.5 years ( range 9 - 15 years ) . - pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : Combined CO2 laser and cryosurgical ablation was practical , cost - effective and provided an excellent aesthetic outcome in dogs with SCCs restricted to the nasal septum , while providing acceptable palliation of local disease . - pubmed
We present 40 patients ( 30 males , 10 females ; mean age 25 years ) diagnosed and treated for CB of the foot from 1975 to 2012 . - pubmed
Ten patients ( 25 % ) had secondary aneurysmal bone cyst . - pubmed
In conclusion , patients with CB of the foot are usually older than 20 years , and males are most affected . - pubmed
BACKGROUND : Children with Kawasaki disease ( KD ) and pyuria have been misdiagnosed with urinary tract infection ( UTI ) . - pubmed
METHODS : We retrospectively reviewed the medical records of children with fever who were under 6 months of age with pyuria , over a 10 - year period ( 2007 - 2017 ) . - pubmed
RESULTS : During the period investigated , 12 ( 9.9 % ) KD patients with sterile pyuria and 378 infants with UTI were included in this study . - pubmed
Combined Therapy With Functional Electrical Stimulation and Standing Frame in Stroke Patients . - pubmed
Thus , the proposed combined therapy could be a useful method for improving standing balance in subacute stroke patients . - pubmed
In our case , a 34 - year - old female patient presented with paresthesia of the third digit . - pubmed
METHODS : Patients with nonmetastatic breast cancer receiving active adjuvant ET were approached by nurse practitioners to complete an anonymous survey at one time point . - pubmed
MATERIALS AND METHODS : We reviewed a prospectively collected database from March 1998 through June 2016 for patients who underwent holmium laser enucleation of the prostate for symptomatic benign prostatic hyperplasia as performed or supervised by a single expert surgeon . - pubmed
Postoperative complications included urethral stricture and bladder neck contracture in 21 ( 1.4 % ) and 30 patients ( 2.1 % ) , respectively . - pubmed
However , both doses of FGY-1153 treatment decreased left ventricular ( LV ) hypertrophy and diastolic dysfunction in hypertensive animals . - pubmed
Analysis of the therapeutic effect of transesophageal echocardiography - guided percutaneous device closure of atrial septal defects via the right internal jugular vein in children . - pubmed
METHODS : Nineteen pediatric patients with secondary ASD underwent TEE - guided ASD device closure via the RIJV from July 22 , 2015 to July 19 , 2017 . - pubmed
RESULTS : In all 19 patients , the ASDs were successfully closed and the occluder was confirmed to have a stable position and good shape , with no residual shunt . - pubmed
This procedure has varied indications , and its advantages include a short operation path , procedural accuracy , minimal trauma , and quick recovery , especially for young patients with large ASDs and cases in which a femoral vein approach is difficult . - pubmed
MATERIALS AND METHODS : All patients with VAP in whom ABT was stopped before death or discharge were included in this 5 - year prospective cohort study . - pubmed
RESULTS : We included 157 of the 316 patients with microbiologically - proven VAP . - pubmed
CONCLUSIONS : PCT - guided ABT adherence appears safe for patients with VAP and is likely to reduce exposure to antibiotics . - pubmed
Our study provides insights on how pig diseases can be spread between pig farms via direct and indirect contact in Nghe An under the various hypothetical scenarios . - pubmed
[ Network meta - analysis on the effects of the acupuncture - related therapy on ovulation rate and pregnancy rate in patients with polycystic ovary syndrome ] . - pubmed
OBJECTIVE : To review systematically the safety and effectiveness of acupuncture - related therapies on ovulation rate and pregnancy rate in patients with polycystic ovary syndrome ( PCOS ) . - pubmed
Eight - week - old male Wistar rats weighing 200 - 250 g were induced with hyperlipidemia via a high - fat diet ( HFD ) comprising 40 % beef tallow . - pubmed
RESEARCH DESIGN AND METHODS : Twenty - eight volunteers with diabetes ( BMI 32.4 + - 5.2 kg / m2 and HbA1c 8.1 + - 1.1 % [ 64.5 + - 11.9 mmol / mol ] ) were randomly assigned to 3Mdiet or 6Mdiet . - pubmed
Predicting variceal bleeding in patients with biliary atresia . - pubmed
The aim of this study is to predict high - risk varices by analyzing various clinical factors , thus improve prognosis of patients with biliary atresia . - pubmed
In this study we investigated the clinicopathologic and molecular features of 7 patients presenting with primary osseous SEF . - pubmed
2,6 - diisopropylphenol ( propofol ) is a commonly used intravenous anesthetic drug , which has been reported to serve an antitumor role in human cancers . - pubmed
The current study aimed to assess the effects of propofol on the biological behaviors of human bladder cancer cells and to elucidate its potential molecular mechanism . - pubmed
DIAGNOSIS : The patient was first diagnosed with macular hole , which closed spontaneously . - pubmed
OUTCOMES : The patient first exhibited a macular hole , which resolved spontaneously . - pubmed
METHODS : We compared the skew of the distribution of power values from five minutes non - rapid eye movement stage N3 sleep for the 5 - 80 Hz , 80 - 250 Hz ( ripple ) , and 250 - 500 Hz ( fast ripple ) bands of epileptic ( located in seizure - onset or irritative zone ) and non - epileptic iEEG channels recorded in patients with drug - resistant focal epilepsy . - pubmed
External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node - negative breast cancer ( RAPID ): a randomised controlled trial . - pubmed
Women aged 40 years or older with ductal carcinoma in situ or node - negative breast cancer treated by breast conserving surgery were randomly assigned ( 1:1 ) to receive either external beam APBI ( 38 5 Gy in ten fractions delivered twice per day over 5 - 8 days ) or whole breast irradiation ( 42 5 Gy in 16 fractions once per day over 21 days , or 50 Gy in 25 fractions once per day over 35 days ) . - pubmed
Acute radiation toxicity ( grade > = 2 , within 3 months of radiotherapy start ) occurred less frequently in patients treated with APBI ( 300 [ 28 % ] of 1070 patients ) than whole breast irradiation ( 484 [ 45 % ] of 1065 patients , p<0 0001 ) . - pubmed
Late radiation toxicity ( grade > = 2 , later than 3 months ) was more common in patients treated with APBI ( 346 [ 32 % ] of 1070 patients ) than whole breast irradiation ( 142 [ 13 % ] of 1065 patients ; p<0 0001 ) . - pubmed
Efficacy of the plantago major L. syrup on radiation induced oral mucositis in head and neck cancer patients : A randomized , double blind , placebo - controlled clinical trial . - pubmed
INTRODUCTION : Oral mucositis is a complication of radiation therapy in cancer patients . - pubmed
We designed a trial to evaluate efficacy of plantago major on symptoms of radiation induced mucositis in cancer patients . - pubmed
Outcome measures were severity of mucositis according to WHO scale and severity of patients ' pain assessed by visual analogue scale . - pubmed
Also patients in intervention group experienced significantly less pain compared to placebo group during radiotherapy period ( p value<0.05 ) CONCLUSION : Plantago major L syrup was effective on the reduction of the symptoms of radiation induced mucositis in patients with head and neck cancers . - pubmed
Surface modified PAMAM dendrimers with gallic acid inhibit , cell proliferation , cell migration and inflammatory response to augment apoptotic cell death in human colon carcinoma cells . - pubmed
Gain of 1q21 is an adverse prognostic factor for multiple myeloma patients treated by autologous stem cell transplantation : A multicenter study in China . - pubmed
BACKGROUND : Autologous stem cell transplantation ( ASCT ) has been recommended as a standard approach for young multiple myeloma ( MM ) patients for decades , even in the era of novel agents . - pubmed
METHODS : In this multicenter study , we retrospectively analyzed 1q21 gain in 446 newly diagnosed MM patients who received at least one ASCT from three large myeloma centers in China . - pubmed
CONCLUSION : In conclusion , 1q21 gain is an adverse prognostic factor for MM patients received ASCT . - pubmed
METHOD : A cross - sectional study was conducted on a total of 61 patients with confirmed Trigeminal neuralgia visiting outpatient neurology clinics of two government teaching Hospitals and two private health facilities in Addis Ababa , Ethiopia between June 2019 and March 2020 . - pubmed
OBJECTIVE : To establish the reliability of the Global Postural System ( GPS ) in assessing pelvic asymmetry and identify the association between pelvic asymmetry parameters and the occurrence of NCLBP in young adults . - pubmed
METHODS : People who were aged between 18 and 30 and were diagnosed with NCLBP were recruited . - pubmed
Diagnostic and prognostic considerations for use of natriuretic peptides in obese patients with heart failure . - pubmed
Nobiletin as a nontoxic dietary citrus flavonoid has anticancer effects in cancer . - pubmed
Here , we investigated the therapeutic potential of XA for rheumatoid arthritis ( RA ) , a debilitating autoimmune inflammatory disease characterized by joint damage , in the complete Freund 's adjuvant ( CFA)-induced arthritis model in rats . - pubmed
AIM To investigate if clinically appropriate renal function monitoring is being undertaken in New Zealand primary care for stroke prevention in non - valvular atrial fibrillation patients prescribed dabigatran etexilate . - pubmed
DISCUSSION There appears to be sub - optimal adherence to renal function monitoring for non - valvular atrial fibrillation patients who receive more than 12 - months ' treatment with dabigatran etexilate in New Zealand primary care . - pubmed
This case - control study enrolled 85 children with ADHD and 96 control subjects . - pubmed
Children with ADHD had significantly higher DMP ( 238.95 nmol / g cre . - pubmed
coli W strains are much lower than those from the strains of E. - pubmed
Selective hypoxia on the left lower lobe of the lung in open - chested dogs at 37 degrees C caused the electromagnetically measured blood flow to the lobe to decrease 51 + /- 5 ( SE)% and its vascular resistance to increase 155 + /- 25 % . - pubmed
However , high slide falciparum rate ( 51.57 ) , child parasite rate ( 40.0 ) , infant parasite rate ( 66.66 ) and spleen rate ( 82.90 ) in the village clearly indicated hyperendemic conditions in the area and hence deaths recorded in the village during the malaria transmission period could be due to malaria only . - pubmed
The studies were carried out in a group of 52 asthmatic patients . - pubmed
We report a patient with a keratoacanthoma of the scalp in which there was invasion of several medium - sized vessels by the tumour at a distance from the main lesion . - pubmed
Apoptosis of murine BW 5147 thymoma cells induced by cold shock . - pubmed
Twenty - five patients with clinical relapse after previous successful angioplasty of iliac or femoro - popliteal arteries were evaluated with repeat angiography . - pubmed
Enzyme activity was measured in 84 normal subjects and in 109 patients with common metabolic bone diseases . - pubmed
The patients in group 3 did not require treatment for pruritus or nausea , a response significantly different ( P less than 0.001 and P less than 0.05 , respectively ) from group 1 or group 2. - pubmed
These results suggested that deficiencies in the HCMV - specific antibody response were not associated with clinically apparent congenital infection and that other factors , such as early virus acquisition during pregnancy , might contribute to the severity of intrauterine HCMV infection . - pubmed
PLS formation appears to indicate a CMI response to M. - pubmed
It is thought that there exists a correlation between the PLS and the lymphocyte transformation test ( LTT ) , both reaching their optimum measurement three months after the M. - pubmed
Body composition , sleeping metabolic rate ( SMR ) , 24 - h energy expenditure ( 24 - EE ) and daily physical activity were determined in 12 obese women during and after 12 weeks of exercise ( 4 h per week on 55 per cent of VO2 max ) and/or energy restriction ( 2.9 - 3.5 MJ / d ) . - pubmed
Numerical index of the discriminatory ability of biotyping for strains of Salmonella typhimurium and Salmonella paratyphi B. - pubmed
Three collections of phage - typed strains of Salmonella typhimurium and Salmonella paratyphi B , previously tested for biotype , were examined . - pubmed
These findings confirm that biotyping affords excellent discrimination of strains of S. - pubmed
DBA mice , susceptible to audiogenic seizures ( AGSs ) in an age - dependent manner , have increased CA activity as compared with C57 ( non - audiogenic seizure susceptible ) mice at 21 and 110 days of age . - pubmed
ACTZ ED50s against maximal electroshock seizures ( MES ) were significantly higher in DBA as compared with C57 mice at 26,36 , and 115 days of age . - pubmed
The life events experienced in the 12 months prior to the first panic attack were studied in 23 patients with a DSM - III diagnosis of panic disorder as well as in 23 healthy subjects matched for age , sex , social and educational level . - pubmed
This normal response in our patients demonstrates that the hypotestosteronaemia in Indian men with myocardial infarction is not due to a primary testicular dysfunction but probably is a result of increased aromatization of testosterone to oestradiol . - pubmed
Between 1970 and 1981 we saw 108 patients with vulvar carcinoma stages I - IV at the university clinic of Graz . - pubmed
A study undertaken to determine the Onchocerca species infecting camels that live in the same localities as cattle in the Dinder Region , Blue Nile Province , Sudan revealed concurrent infections with the bovine parasites Onchocerca armillata in the thoracic aorta , brachiocephalic trunks and brachial arteries and Onchocerca gutturosa in the ventral side of the lamellar parts of the ligamentum nuchae . - pubmed
Babe Ruth , tobacco , alcohol , and cancer . - pubmed
An ultrasound study of the thyroid was performed in 55 patients who were admitted to be treated surgically for the goiter . - pubmed
Sixty - six patients were admitted from January 1980 through December 1983 with double fractures of the pelvic ring that involved the posterior elements . - pubmed
We conclude that the patient with multiple trauma without unstable pelvic fracture should undergo immediate external fixation to decrease morbidity and mortality rates and limit soft tissue damage . - pubmed
[ Motor - evacuatory function of the gastrointestinal tract in patients with dumping syndrome ] . - pubmed
The efficacy of 2 - chloro-4 - nitrobenzamide for the prevention and control of coccidiosis in chickens . - pubmed
Factors affecting testis weight in normal and cryptorchid horses . - pubmed
Effect of volume expanders on the lysability of ex vivo thrombi in the rabbit . - pubmed
Chironomids , of which approximately 10,000 species exist , are reported to cause severe immediate type allergic diseases in man . - pubmed
Selenium suppresses the metabolism of benzo [ a ] pyrene by rat - liver extracts , and exerts a dual effect on its mutagenicity . - pubmed
Effect of diet on human muscle weakness following prolonged exercise . - pubmed
It is concluded that changes in muscle glycogen alone do not alter the isometric force generating capacity of human muscle , but when combined with prolonged exercise low muscle glycogen enhances exercise - induced muscle weakness . - pubmed
In nine healthy subjects a 2 % calcium solution was continuously infused intravenously and a hypercalcaemic state was maintained . - pubmed
Isolation , characterization and biological activities of verotetrone from a mutant strain of Streptomyces aureofaciens . - pubmed
A new metabolite denoted as verotetrone was isolated from the mycelium of the mutant strain Streptomyces aureofaciens NMG-2 . - pubmed
Thirty - nine patients with invasive bladder cancer were treated using a new approach to adjuvant radiation therapy . - pubmed
The clinical records of 61 patients who underwent extended surgery , including resection of parietes or other viscera , from 1965 to 1977 for cancer of the rectum and sigmoid were reviewed . - pubmed
Local or distant recurrence occurred in 66 per cent of patients with microscopic infiltration and in 24 per cent of patients without microscopic infiltration . - pubmed
Induction of anti - tubular- and anti - glomerular - basement - membrane antibodies in guinea pigs sensitized to 2 , 4 - dinitrochlorobenzen with reference to tubulo - interstitial and glomerular nephritis . - pubmed
Cells that grew in soft agar also produced undifferentiated mesenchymal tumors in preirradiated nude mice . - pubmed
HR 466 ( 16 , 16 - dimethyl-18 - oxa - PGA2 ) , the best compound out of this series was active for 5 - 6 hours after oral administration of 0 , 1 mg / kg to conscious renal hypertensive dogs . - pubmed
Structural variations within the trans - delta 2 - 11 - deoxy - PGE1 - series , in both side chains , gave HR 601 ( trans - delta2 - 15alpha - acetoxy-16 , 16 - dimethyl-18 - oxa-11 - deoxy - PGE1 - methylester ) which was orally active in the hypertensive dog with similar activity to HR 466 . - pubmed
Fatal haemoptysis in Salmonella typhimurium septicaemia -- a cautionary tale . - pubmed
Septicaemia and mycotic aneurysm may occur in a patient who is an enteric - carrier of Salmonella typhimurium . - pubmed
We report such a case of an elderly man who presented with chest pain and fatal massive haemoptysis from a likely mycotic thoracic aneurysm . - pubmed
Toxicity of myristic acid analogs toward African trypanosomes . - pubmed
Patients were seizure - free and did not show EEG abnormalities at repeated controls in the last 5 years , so that interfering effects of seizures were possibly excluded . - pubmed
[ Current problems in the intensive therapy of patients with acute pneumonia ] . - pubmed
Chronic hepatitis , representing the category which could benefit from interferon alpha treatment , was found in 24 patients . - pubmed
Severe complications of the hepatitis were found in 4 % of the children , including hepatocellular carcinoma and cirrhosis . - pubmed
Platelet - activating factor antagonist BN52021 improves survival in normothermic liver ischemia in rats . - pubmed
The human microvascular anastomosis represents a localized environment with strongly thrombotic tendencies . - pubmed
In order to evaluate the prevalence and the clinical manifestations of this complication , all patients with spontaneous pneumothorax managed with chest tube drainage were evaluated over an 8 - yr period ( 1986 - 1994 ) . - pubmed
A 43 - year - old man suffered generalized convulsions following severe headache . - pubmed
METHODS : One hundred women with pure stress urinary incontinence were enrolled in a 6 - month study . - pubmed
Bothersome vaginal or urethral irritation occurred in 12 % of patients . - pubmed
Differences in extracellular matrix components and cell density during normal and dexamethasone - treated secondary palate development in two strains of mice with different susceptibility to glucocorticoid induced - clefting . - pubmed
An histological and histochemical study analyzing cell density and distribution of extracellular matrix ( ECM ) components in two stages of developing secondary palate and in two strains of mice with different H-2 backgrounds was undertaken to investigate differences between a strain that is susceptible to glucocorticoid - induced cleft palate ( A / Sn ) and one that is resistant ( C57 / BL ) . - pubmed
fragilis group ( from 14 % in 1992 to 29 % in 1996 ) and also among strains of clostridia ( 32 % ) , P. - pubmed
A phase II trial of interferon alpha-2a and carboplatin in patients with advanced malignant mesothelioma . - pubmed
We defined the antitumor activity , toxicity , and tolerability of a combined chemoimmunotherapy approach in patients with advanced malignant mesothelioma using daily low - dose interferon alpha-2a and carboplatin given every 4 weeks . - pubmed
This was a phase II study of 15 patients with surgically unresectable or metastatic malignant mesothelioma . - pubmed
Fifteen patients were assessable for toxicity and 14 for response . - pubmed
Forty - four patients were referred because of myocardial ischemia related to the stented artery . - pubmed
There is also an urgent need to update existing guidelines and perhaps even provide specific guidelines for the treatment and long - term management of patients with diabetes and hypertension . - pubmed
These unique properties of the 14 - repeat allele may confer selective advantages in diabetic individuals , which may delay or prevent microvascular complications of diabetes . - pubmed
BACKGROUND AND PURPOSE : To define the effects of three commonly used anesthetic agents -- sodium pentobarbital given intraperitoneally , and inhaled halothane and methoxyflurane -- on the pathogenesis of pneumococcal pneumonia and bacteremia in an experimental murine model . - pubmed
METHODS : Swiss outbred mice were anesthetized with either sodium pentobarbital , halothane , or methoxyflurane before intranasal infection with Streptococcus pneumonia . - pubmed
CONCLUSION : Effects of anesthesia on murine models of pneumonia should be considered in the design and interpretation of studies of pneumococcal pathogenesis . - pubmed
Based on DNA relatedness data , the type strains of Thermoactinomyces intermedius , Thermoactinomyces putidus , Thermoactinomyces dichotomicus and Thermoactinomyces peptonophilus were considered to be distinct species of the genus Thermoactinomyces . - pubmed
However , the relationship between the type strains of Thermoactinomyces vulgaris and Thermoactinomyces candidus and the relationship between the type strains of Thermoactinomyces sacchari and Thermoactinomyces thalpophilus were reevaluated from levels of DNA - DNA relatedness . - pubmed
Eight atherosclerotic male adult New Zealand White rabbits weighing 4 - 6 kg were used in these studies . - pubmed
Viral co - infection does not reduce the efficacy of vaccination against non - typeable Haemophilus influenzae middle ear infection in a rat model . - pubmed
Our results suggest that high - dose aspirin exerts significant toxicity to guinea pig myocardium and normal dose aspirin may cause peroxidation in the human erythrocytes due to its oxidant potential . - pubmed
METHODS : Tumors were established in the floor of mouth in C3H / HeJ immunocompetent mice . - pubmed
Comparative analysis of two - dimensional protein patterns in malignant and normal human breast tissue . - pubmed
Malignant and normal human breast tissue were compared by evaluating two - dimensional polyacrylamide gel electrophoresis ( 2D - PAGE ) maps of frozen tissue samples . - pubmed
We report the case of a 90 - year - old diabetic patient who developed simultaneous avulsions of the patellar and tibial insertions . - pubmed
CASE REPORT : A 90 - year - old woman with noninsulin - dependent diabetes mellitus fell on her left knee and was subsequently unable to extend the knee despite normal quadriceps contraction . - pubmed
DISCUSSION : Bifocal disruption of the extensor system is a rare event in adults . - pubmed
In fact , strongly reactive TA - specific cytolytic T - lymphocytes and tumour - infiltrating lymphocytes ( TIL ) can be identified and expanded ex vivo from patients with metastatic melanoma vaccinated with melanoma - associated antigens . - pubmed
METHODS : Resting electroencephalogram was recorded in 38 unmedicated subjects with major depressive disorder and 18 normal comparison subjects , and analyzed with a tomographic source localization method that computes the cortical three - dimensional distribution of current density for standard electroencephalogram frequency bands . - pubmed
In melancholic subjects , this effect was particularly pronounced for severe depression , and right frontal activity correlated positively with anxiety . - pubmed
This metabolic footprint was relatively constant in all patients regardless of age , seizure history , or therapies and therefore constitutes a radiological signature of the disease . - pubmed
All macaques , including one naive macaque , were exposed to SIV(mac251 ) by the intrarectal route and sacrificed 48 h after infection . - pubmed
Effect of vitamin C supplementation on reduced glutathione and malondialdehyde in patients with acute myocardial infarction . - pubmed
Individuals with Williams syndrome typically show relatively poor visuospatial abilities in comparison to stronger verbal skills . - pubmed
Individuals with Williams syndrome show an atypical processing style on tests of construction , which does not affect tests of perception . - pubmed
Staphylococcus epidermidis is the most frequent cause of nosocomial sepsis and catheter - related infections , in which biofilm formation is considered to be the main virulence mechanism . - pubmed
Reduction of cardiac output by ligation of the inferior vena cava in patients with atrial septal defects complicated by pulmonary hypertension ; a report of 2 cases . - pubmed
Studies on the effect of beers of Penicillium funiculosum against Columbia SK virus infections in mice . - pubmed
[ Important stages and aspects in the study of human brucellosis abroad and in the USSR . - pubmed
( 100th anniversary of the differentiation of brucellosis as a new human disease ) ] . - pubmed
In male rats , pretreatment for 20 days with very low ( 0.5 , 1 % , v / v ) but not with high ( 5 , 10 % , v / v ) oral doses of ethanol delayed the initiation and reduced the duration of narcosis induced by an acute high intraperitoneal ( i.p . ) - pubmed
A higher dose of sulpiride ( 10 mg / kg ) prolonged the duration of narcosis in rats pretreated with high - dose ethanol and reduced the number of conditioned avoidance responses in the shuttle - box paradigm . - pubmed
First in vivo measurements of DAT with single photon emission computed tomography ( SPECT ) in ADHD patients revealed an elevation of striatal DAT density . - pubmed
No differences in DAT density between the left and right side and between putamen and caudate nucleus have been found in [ 99mTc ] TRODAT-1 SPECT of ADHD patients . - pubmed
Patients with ADHD and with a history of nicotine abuse both displayed lower values of DAT density in [ 99mTc ] TRODAT-1 SPECT than non - smokers with ADHD . - pubmed
DAT seem to be elevated in non - smoking ADHD patients suffering from the purely inattentive subtype of ADHD as well as in those with the combined or purely hyperactive / impulsive subtype . - pubmed
This study assessed the efficacy and safety of liraglutide after 12 weeks of treatment in type 2 diabetic patients . - pubmed
RESEARCH DESIGN AND METHODS : A double - blind , randomized , parallel - group , placebo - controlled trial with an open - label comparator arm was conducted among 193 outpatients with type 2 diabetes . - pubmed
Patients treated with glimepiride had decreased HbA(1c ) and fasting glucose , but slightly increased body weight . - pubmed
METHODS : In a nationwide study on JT , 123 patients were re - examined 10 y ( range 4 to 21 y ) after diagnosis . - pubmed
Two patients with toxic adenoma were excluded . - pubmed
AIMS / HYPOTHESIS : The aim of this study was to assess whether the diabetogenicity of areca nut ( Areca catechu or ' betel - nut ' ) , which has previously been demonstrated experimentally in mice , independently contributes to the risk of hyperglycaemia or type 2 diabetes in men in Taiwan , where the habit has become established relatively recently . - pubmed
RESULTS : Compared with non - chewers , areca nut chewers had higher age - adjusted prevalence rates for hyperglycaemia ( 11.4 % vs 8.7 % ) and type 2 diabetes ( 10.3 % vs 7.8 % ) . - pubmed
Extracellular enzymatic activity and serotype of Cryptococcus neoformans strains isolated from AIDS patients in Brazil . - pubmed
External otitis caused by infection with Pseudomonas aeruginosa or Candida albicans cured by use of a topical group III steroid , without any antibiotics . - pubmed
CONCLUSIONS : Irrespective of the microbial agent , group III steroid solution cured external otitis efficiently in a rat model . - pubmed
OBJECTIVE : External otitis , caused by infection with either Pseudomonas aeruginosa or Candida albicans , was established in a rat model and the treatment efficacy of a group III steroid solution was studied . - pubmed
Transport deficient ( TR- ) hyperbilirubinemic rats are resistant to acetaminophen hepatotoxicity . - pubmed
This mutant strain of Wistar rats has impaired biliary excretion of organic anions and increased hepatic glutathione . - pubmed
Therefore , the susceptibility of TR- rats to APAP hepatotoxicity was investigated . - pubmed
TR- rats treated with buthionine sulfoximine and APAP showed dramatic increases in hepatotoxicity . - pubmed
A total of 53 consecutive patients , 34 with early MI ( group 1 ) and 19 with recent MI ( group 2 ) , who had had no prior thrombolytic therapy were included . - pubmed
Therefore , investigation of longer utilization of anti - platelet and anti - inflammatory agents for patients following AMI might be worthwhile . - pubmed
It has been shown that there is an increased proportion of T regs in several different human malignancies , although the actual mechanism remains unclear . - pubmed
The aim of this study was to determine the prevalence of Mycoplasma genitalium in male urethritis and in vaginal specimens of pregnant women . - pubmed
Urethral specimens obtained from 37 men presenting with urethritis and vaginal specimens from 50 consecutive pregnant women were tested for the presence of M. - pubmed
The urethral specimens were also examined for the presence of Neisseria gonorrhoeae , Chlamydia trachomatis and Ureaplasma sp whereas the vaginal microbiota and the presence of genital mycoplasma were investigated in the vaginal specimens . - pubmed
Serotonin and 5 - hydroxy - indole - acetic acid contents in dorsal raphe and suprachiasmatic nuclei in normal , malnourished and rehabilitated rats under 24 h of sleep deprivation . - pubmed
Then , all animals were sacrificed by decapitation . - pubmed
BACKGROUND : The management of patients with colorectal cancer has changed appreciably over the last 16 years . - pubmed
This data was compared with a retrospective data set that included all patients treated with colorectal cancer at the same institution from 1989 to 1995 . - pubmed
There were more patients with rectal cancer and stage I cancer in the study group . - pubmed
and a decrease in the 5 year recurrence rate for patients undergoing curative resections ( 17 % [ 95 % CI 12%-20 % ] vs 42 % [ 95 % CI 36%-49 % ] , p & lt ; 0.001 ) . - pubmed
There was also a decrease in local recurrence in patients with rectal cancer ( 8.8 % [ 95 % CI 4.5%-13.1 % ] vs 33.6 % [ 95 % CI 23.6%-43.6 % ] , p & lt ; 0.001 ) . - pubmed
Q fever is a worldwide - occurring zoonosis caused by Coxiella burnetii . - pubmed
Whereas serology is the reference diagnostic method for Q fever , detection of C. - pubmed
These results are the first to report alterations in expression of muscle - enriched microRNAs in skeletal muscle of the mdx mouse , suggesting microRNAs may have a role in the pathophysiology of muscular dystrophy . - pubmed
We operated 52 patients ranging in age from 29 to 60 , who presented with prolapse of the nucleus pulposus ( 21 patients ) , instability ( 8 patients ) , lumbar stenosis ( 11 patients ) , and recurrent discopathy with spondylolisthesis ( 12 patients ) . - pubmed
Cytotoxicity , metabolism and cellular uptake of the mycotoxin deoxynivalenol in human proximal tubule cells and lung fibroblasts in primary culture . - pubmed
At the level of the whole animal , the toxic effects of the mycotoxin deoxynivalenol ( DON ) range from causing diarrhoea , vomiting , gastro - intestinal inflammation to necrosis of several tissues . - pubmed
Although DON has been tested in different human and animal cell lines for its cytotoxicity , these tests might be limited due to the disadvantages of cell lines ( e.g. - pubmed
It could be demonstrated that DON has a distinct cytotoxic effect on human primary cells . - pubmed
In the Natalizumab Safety and Efficacy in Relapsing - Remitting Multiple Sclerosis ( AFFIRM ) trial , infusion - related hypersensitivity reactions developed in 4 % of patients , usually within 2 hours after starting the infusion . - pubmed
PATIENT : A 23 - year - old man with relapsing - remitting multiple sclerosis developed a fever , arthralgias , urticarial exanthema , and a swollen lower lip during several days after his second infusion of natalizumab . - pubmed
RESULTS : The patient developed a delayed , serum sickness - like , type III systemic allergic reaction to natalizumab . - pubmed
CONCLUSION : Clinicians and patients should be alert not only to immediate but also to significantly delayed substantial allergic reactions to natalizumab . - pubmed
Safety and immunogenicity profile of the concomitant administration of ZOSTAVAX and inactivated influenza vaccine in adults aged 50 and older . - pubmed
OBJECTIVES : To evaluate the safety and immunogenicity of ZOSTAVAX administered concomitantly with inactivated influenza vaccine or sequentially in adults aged 50 and older . - pubmed
Estimated GMT ratios ( concomitant / sequential ) for influenza strains A(H1N1 ) , A ( H3N2 ) , and B were 0.9 ( 95 % CI=0.8 - 1.1 ) , 1.1 ( 95 % CI=0.9 - 1.3 ) , and 0.9 ( 95 % CI=0.8 - 1.1 ) , respectively , and SCRs were comparable across both groups , with more than 85 % achieving titers of 1:40 or greater , meeting regulatory criteria . - pubmed
As a new approach , we evaluated the protolerogenic potential of calcitriol and dexamethasone in acute T helper ( Th)1 - mediated colitis in mice . - pubmed
Lymphangitis in a Portuguese patient infected with Rickettsia sibirica . - pubmed
OBJECTIVE : Congenital hyperinsulinism , usually associated with severe neonatal hypoglycemia , may progress to diabetes , typically during the 4th decade of life in nonpancreatectomized patients . - pubmed
We aimed to genotype the ATP - sensitive K(+ ) channel in a 10.5 - year - old girl presenting with overt diabetes following hyperinsulinism in infancy . - pubmed
RESEARCH DESIGN AND METHODS : A female aged 10.5 years presented with new - onset , antibody - negative diabetes ( A1C 10.6 % ) . - pubmed
In this study the authors examined the efficacy of TUDCA on preserving rod and cone function and morphology at postnatal day 30 ( P30 ) in the rd10 mouse , a model of RP . - pubmed
CONCLUSIONS : TUDCA is efficacious and safe in preserving vision in the rd10 mouse model of RP when treated between P6 and P30 . - pubmed
At P30 , a developmental stage at which nearly all rods are absent in the rd10 mouse model of RP , TUDCA treatment preserved rod and cone function and greatly preserved overall photoreceptor numbers . - pubmed
Escape behaviour in rodents closely mimics panic attacks in humans . - pubmed
This study evaluates the effects of age and chronic dietary restriction ( DR ) on nonneoplastic diseases in rats that were fed the American Institute of Nutrition ( AIN)-93 M purified diet . - pubmed
Nonneoplastic disease profiles were developed to clarify whether the AIN-93 M diet fulfills long - term nutritional requirements of rats . - pubmed
At 58 weeks of age , the 2 main types of nonneoplastic diseases in AL rats were liver vacuolization and cardiomyopathy . - pubmed
At 114 weeks of age , the most common lesions in AL rats were cardiomyopathy , nephropathy , liver vacuolization , and degeneration with renal failure and genitourinary infections causing the greatest mortality . - pubmed
Nonneoplastic diseases accounted for 28.9 % and 0.0 % of total mortalities in the AL and DR groups , respectively ; however , there was a higher incidence of unknown deaths in the DR rats ( 52.6 % ) compared to AL rats ( 28.9 % ) , which may have limited the success of DR to improve survival . - pubmed
Although the AIN-93 M diet supported chronic rat growth , alterations in some dietary component concentrations may be required to lower body weight in chronic rodent and human studies . - pubmed
Factors such as diet composition and digestibility may alter nonneoplastic diseases and mortality in rats and humans in a similar fashion . - pubmed
These lower the efficiency of treatment , increase the likelihood of drug resistance in Mycobacterium tuberculosis , and contribute to the chronic pattern of the tuberculosis process , continuously replenishing the pool of untreatable patients with tuberculosis and bacterial discharge . - pubmed
After 6 week period of the renal artery clipping procedure , eight 2K1C rats developed stable hypertension . - pubmed
The differences between the hypertensive rats and the control group concerned not only the number of endocrine cells but also their distribution . - pubmed
Flokalin was introduced in dose 0.1 mg / kg of animal body weight which practically did not change the parameters of hemodynamic in conditions of normoxia . - pubmed
Immunization against a lymphoid tumor of the chicken ; use of miscellaneous tissues . - pubmed
Resistance to multiple drugs is a serious limitation to chemotherapy treatment of human cancers . - pubmed
RESULT : children with sensorineural and conductive hearing loss presented a lower performance in all of the SAAT results when compared to the control group . - pubmed
Stimulus similarity and encoding time influence incidental recognition memory in adult monkeys with selective hippocampal lesions . - pubmed
Recognition memory impairment after selective hippocampal lesions in monkeys is more profound when measured with visual paired - comparison ( VPC ) than with delayed nonmatching - to - sample ( DNMS ) . - pubmed
To clarify this issue , we assessed the impact of stimuli similarity and encoding duration on the VPC performance in monkeys with hippocampal lesions and sham - operated controls . - pubmed
Persistent epithelial barrier alterations in a rat model of postinfectious gut dysfunction . - pubmed
CONCLUSIONS & amp ; INFERENCES : Trichinella spiralis infection in rats , at late stages , results in persistent postinfectious intestinal barrier dysfunctions and mucosal mastocytosis , with other signs suggestive of a low grade inflammation . - pubmed
CASE REPORT : We report the case of a 35 - year - old man who presented with symptoms of acalculous gallbladder disease with high levels of amylasuria . - pubmed
METHODS : Between April 2006 and February 2010 , we performed laparoscopic resection for SMTs located near the EGJ ( within 3.0 cm from the EGJ ) in ten consecutive patients . - pubmed
Out of seven exogastric resections , an FRT was used in five patients with posterior tumors near the EGJ . - pubmed
It was examined a cohort of patients with cystic fibrosis of the southern Italy , 24 patients aged between 12 and 44 years , 12 females and 12 males with BMD assessment methods like dual energy X - rays ( DXA ) and calcaneal ultrasound densitometry in a few cases , ultrasonography was used jointly . - pubmed
[ The role of hypercholesterolemia in the outbreak of Alzheimer ' s disease and the treatment effect of Sibraea angustata extract ] . - pubmed
OBJECTIVE : To observe the role of hypercholesterolemia in the outbreak of Alzheimer ' s disease ( AD ) and the treatment effect of Sibraea angustata extract . - pubmed
The extract of Sibraea angustata can not only reduce the content of cholesterol in the AD animal effectively but also improve brain tissue pathology . - pubmed
Genetic diversity of clinical and environmental Vibrio parahaemolyticus strains from the Pacific Northwest . - pubmed
Since 1997 , cases of Vibrio parahaemolyticus - related gastroenteritis from the consumption of raw oysters harvested in Washington State have been higher than historical levels . - pubmed
Production and degradation of extracellular matrix in reversible glomerular lesions in rat model of habu snake venom - induced glomerulonephritis . - pubmed
We investigated the mechanism of development and repair process of glomerular injury in a rat model of habu snake ( Trimeresurus flavoviridis ) venom ( HSV)-induced glomerulonephritis . - pubmed
Glomerulonephritis was induced in rats by intravenously injecting HSV at 3 mg / kg . - pubmed
[ Assessment of multimodal effect of cytoflavin in the acute brain stroke in patients with metabolic syndrome ] . - pubmed
A phase III trial of TTFields monotherapy compared to active chemotherapy in recurrent glioblastoma patients established that TTFields therapy is associated with minimal toxicity , better quality of life , and comparable efficacy to chemotherapy . - pubmed
RESULTS : Seven patients had operations due to late - presenting CHD in our institution over 30 years . - pubmed
There was no recurrence in any of the patients on follow - up . - pubmed
We found that compared to wild - type mice , bacterial colony forming units 48 h after intranasal infection with K. - pubmed
Acquired absolute vitamin K deficiency in a patient undergoing warfarin therapy . - pubmed
A 78 - year - old woman was admitted to our hospital because of dyspnea and sore throat diagnosed as pharyngitis 1 week before admission . - pubmed
Since the coagulopathy responded to intravenous VK administration , the patient was clinically diagnosed with warfarin - related relative VKD . - pubmed
Severe coagulopathy in patients undergoing warfarin therapy is primarily caused by , relative VKD . - pubmed
Human postural control , which relies on information from vestibular , visual , and proprioceptive inputs , degrades with aging , and falls are the leading cause of injury in older adults . - pubmed
Deglutition - Induced Real - Time Directional Displacements in Head - and - Neck Cancer Patients --- Dynamic Volume Shuttle Imaging Analysis . - pubmed
METHODS : Thirty - six adult male Wistar rats , were randomly assigned to groups of normal control ( n = 6 ; no manipulation ) and liver fibrosis ( n = 30 ; given a subcutaneous injection of 40 % chronic carbon tetrachloride ( CCl4 ) ) . - pubmed
Ebola causes highly lethal hemorrhagic fever in humans with no licensed countermeasures . - pubmed
The respiratory tree tissue of the sea cucumber is an excellent material for studying aestivation , undergoing obvious atrophy during aestivation . - pubmed
PATIENTS AND METHODS : Seventeen eyes of 15 consecutive patients diagnosed with PCV based on typical clinical and angiographic findings were imaged with macular SD - OCT including line scans passing through the polyps . - pubmed
PURPOSE OF REVIEW : This study focuses on the epidemiology and management of mucormycosis in hematopoietic stem cell transplant patients , a life - threatening mold infection whose incidence has increased over the past decades . - pubmed
RECENT FINDINGS : Mucormycosis may occur in hematopoietic stem cell transplant recipients with severe graft - versus - host disease , steroids , neutropenia , iron overload , diabetes , and malnutrition , or those who received antifungals not active against Mucorales . - pubmed
The reversed halo sign on chest computed tomography has been associated to mucormycosis in neutropenic patients , but is not pathognomonic . - pubmed
Attachment , penetration and early host defense mechanisms during the infection of filamentous brown algae by Eurychasma dicksonii . - pubmed
BACKGROUND : Patients with symptoms that impersonate a stroke but are later found to have an alternate diagnosis are termed stroke mimics . - pubmed
Stroke mimics are described and compared with acute ischemic stroke patients for demographics , clinical characteristics , and bleeding complications . - pubmed
RESULTS : We identified 38 stroke mimic ( 12 % ) and 285 ischemic stroke ( 88 % ) t - PA - treated patients . - pubmed
Compared with ischemic stroke patients , mimic patients were younger , more often female , and reported a history of stroke more often . - pubmed
There were no intracerebral hemorrhages or deaths in the mimic patients but there were 2 systemic hemorrhages ( 5.2 % ) . - pubmed
METHODS : A single - blind , two - parallel group , randomized trial was conducted at three medical centers ( Guangzhou , China ) , including patients with both biopsy - confirmed hepatocellular carcinoma and lung metastasis . - pubmed
METHODS : From October 2005 to August 2013 , we performed LATG with lymph - node dissection and Roux - en - Y reconstruction using the overlap method in 77 patients with gastric cancer . - pubmed
There were no deaths , and morbidity rate was 13 % , including one patient ( 1 % ) who developed anastomotic stenosis . - pubmed
BACKGROUND : Stroke is a significant complication in patients supported with continuous - flow left ventricular assist devices ( CF - LVAD ) and hypertension is a significant risk factor for stroke , but the association between blood pressure and stroke in LVAD patients is not well characterized . - pubmed
These results identify management of hypertension as a potential modifiable risk factor for reducing the incidence of stroke in patients supported by CF - LVAD . - pubmed
INTRODUCTION : Nipple - sparing mastectomy has become a contemporary surgical treatment that achieves improved cosmetic outcomes for patients with breast cancer in Western countries . - pubmed
METHODS : Between 2006 and 2011 , 42 patients with breast cancer who underwent 44 nipple - sparing mastectomy operations with immediate reconstruction at the Tri - Service General Hospital were reviewed . - pubmed
CONCLUSION : Nipple - sparing mastectomy is a safe procedure in properly selected patients with breast cancer . - pubmed
In addition , we have identified new genetic variants of the Chinese Crested dog that will contribute to further whole - genome sequencing studies aimed to identify mutations associated with monogenic diseases with autosomal recessive inheritance . - pubmed
Intracranial application of near - infrared light in a hemi - parkinsonian rat model : the impact on behavior and cell survival . - pubmed
OBJECT The authors of this study used a newly developed intracranial optical fiber device to deliver near - infrared light ( NIr ) to the midbrain of 6 - hydroxydopamine ( 6 - OHDA)-lesioned rats , a model of Parkinson ' s disease . - pubmed
It exhibits efficacious anti - ischemic and anti - atherosclerosis activities in rats . - pubmed
A fecal metabolomics based on Liquid Chromatography - Mass Spectrometry combined with clinical histopathology and blood lipid estimation was employed to assess the efficacy and the metabolic changes caused by administration of DBZ in atherosclerotic rats . - pubmed
Nevertheless , atherosclerotic rats administered both DBZ ( at a dose of 40 mg kg(-1 ) ) and simvastatin ( at a dose of 20 mg kg(-1 ) ) showed good therapeutic effects . - pubmed
The results of the metabolomics studies showed that 55 differential metabolites such as sebacic acid , enterodiol , nonanedioic acid , dodecanedioic acid , cholic acid , 13 ( S )- HPODE , deoxycholic acid , some phosphatidylglycerol and phosphatidic acids were found , indicating that abnormal metabolism occurred in the pathways of fatty acid oxidation , linoleic acid metabolism , bile acid biosynthesis and glycerophospholipid metabolism in atherosclerotic rats . - pubmed
The 75 - year - old female patient experienced the trauma at the age of 4 . - pubmed
Sixty human teeth samples were prepared from freshly extracted , unrestored , caries free , nonattrited maxillary first premolars . - pubmed
Children with LRTI were found to have significantly lower mean vitamin D levels as compared to controls There was likewise a correlation between vitamin D levels and incidence and severity of LRTI . - pubmed
Recovery of a 10 - year - old girl from methicillin - resistant Staphylococcus aureus sepsis in response to low - dose ceftaroline treatment . - pubmed
Various bacterial species were isolated from multiple wounds , and methicillin - resistant Staphylococcus aureus ( MRSA ) was one among them . - pubmed
After the amputation of her lower legs , she developed MRSA sepsis , which was successfully treated with a relatively low dosage of ceftaroline ( Zinforo ( ) /Teflaro ( ) ; 2x9 mg / kg / d ) , although the bacterial isolate 's minimal inhibitory concentration ( 1.5 - 4 mg / L ) suggested a decreased susceptibility . - pubmed
Determinants of hypofibrinolysis in patients with digestive tract cancer . - pubmed
Furthermore , studies in murine models and humans have identified the bone marrow ( BM ) as a previously neglected site of diabetic end - organ damage , characterized by microangiopathy , neuropathy , fat deposition , and inflammation . - pubmed
A better understanding of the molecular and cellular processes that govern the BM stem cell niche , cell mobilization , and kinetics in peripheral tissues may uncover new therapeutic strategies for patients with diabetes . - pubmed
Patients with RE also exhibited significant declines in esophageal mucin secretion ; however , after healing of RE with rabeprazole , this rate increased significantly . - pubmed
The purpose of this study is to longitudinally characterize MRI features after LITT in patients with drug - resistant epilepsy , primarily in the setting of mesial temporal sclerosis . - pubmed
Previous studies have demonstrated that oridonin , a tetracyclic diterpenoid compound extracted from Rabdosia rubescens , inhibits proliferation and induces apoptosis in several tumor cell lines . - pubmed
PARTICIPANTS : A total of 100 adolescents , between the ages of 12 and 18 years , who sustained concussion due to sports . - pubmed
RESULTS : Twenty - four patients ( 24 % ) were prescribed medications in this study , all of whom reported headache at the time of medication prescription . - pubmed
It remains the drug of choice for the treatment of serious infections caused by methicillin - resistant Staphylococcus aureus . - pubmed
Only three of the eight patients received nephrotoxins prior to development of nephrotoxicity . - pubmed
METHODS : This was a retrospective cohort study of severe sepsis patients admitted to the hospital from the ED between January 2005 and February 2010 . - pubmed
Mammalian milk allergy : case presentation and review of prevalence , diagnosis , and treatment . - pubmed
We simultaneously modelled all fimasartan plasma concentrations and 24 - h ambulatory blood pressure monitoring ( ABPM ) data from 39 patients with essential hypertension and 56 healthy volunteers . - pubmed
Topical evening primrose oil as a possible therapeutic alternative in children with molluscum contagiosum . - pubmed
Resveratrol improved detrusor fibrosis induced by mast cells during progression of chronic prostatitis in rats . - pubmed
After rat model of CP is established by subcutaneously injecting DPT vaccine , rats are treated with resveratrol . - pubmed
Circulating influenza viruses evade neutralization in their human hosts by acquiring escape mutations at epitopes of prevalent antibodies . - pubmed
CONCLUSIONS : UAS is highly effective for OSA treatment in selected patients with an apnea - hypopnea index between 15 and 65 events per hour and higher body mass index . - pubmed
OBJECTIVES : To describe a cohort of classic Kaposi sarcoma in a low - endemic area for KSHV , to highlight the features of CKS in MSM and identify prognostic factors . - pubmed
METHODS : A total of 42 VKH patients ( 84 eyes ) and 45 normal controls ( 90 eyes ) were included in this study . - pubmed
All of the patients showed active uveitis and were referred to us within 2 months after disease onset . - pubmed
RESULTS : All investigated VKH patients showed a significantly decreased visual acuity and retinal structural changes before treatment . - pubmed
Dielectric and thermodynamic study of Hb exploring Moringa Oleifera leaves extract potential against radiation damage . - pubmed
18F - FDG uptake in enlarged lymph nodes is always suspicious , especially in cancer patients . - pubmed
We report a case of hypermetabolic internal mammary lymphadenopathy in a breast cancer patient who was previously treated with bilateral mastectomy and implants . - pubmed
Vigilant PET interpretation is required in breast cancer patients who have evidence of breast implant rupture . - pubmed
Clinical features and corneal optical anisotropies in a rabbit model of limbal stem cell deficiency . - pubmed
PURPOSES : To investigate the intra - laboratory reproducibility of clinical features and to evaluate corneal optical anisotropies in a rabbit model of limbal stem cell deficiency . - pubmed
METHODS : Limbal injury was induced in the right eye of 23 adult New Zealand White rabbits using a highly aggressive protocol that combined 360 degrees limbal peritomy , keratolimbectomy , alkaline chemical burn , and mechanical removal of the epithelium . - pubmed
CONCLUSIONS : These results suggest that rabbit models of limbal stem cell deficiency must be rigorously screened for use in preclinical studies to ensure experimental homogeneity because protocols used to create limbal stem cell deficiency could be not associated with good intra - laboratory reproducibility of clinical features . - pubmed
Partial findings released from that study showed significantly increased incidences and/or trends for gliomas and glial cell hyperplasias in the brain and schwannomas and Schwann cell hyperplasias in the heart of exposed male rats . - pubmed
These results , as well as the findings of significantly increased DNA damage ( strand breaks ) in the brains of exposed rats and mice , reduced pup birth weights when pregnant dams were exposed to GSM- or CDMA - modulated RFR , and the induction of cardiomyopathy of the right ventricle in male and female rats clearly demonstrate that the null hypothesis has been disproved . - pubmed
The NTP findings are most important because the International Agency for Research on Cancer ( IARC ) classified RFR as a " possible human carcinogen " based largely on increased risks of gliomas and acoustic neuromas ( which are Schwann cell tumors on the acoustic nerve ) among long term users of cell phones . - pubmed
In contrast to those criticisms , an expert peer - review panel recently concluded that the NTP studies were well designed , and that the results demonstrated that both GSM- and CDMA - modulated RFR were carcinogenic to the heart ( schwannomas ) and brain ( gliomas ) of male rats . - pubmed
The best growth of strain FW-11 T occurred at 30 C and pH 6.0 - 7.0 . - pubmed
The average nucleotide identity relatedness values between strain FW-11 T and the two type strains ( S. - pubmed
We did a prospective study and included all patients with acute flaccid weakness and documented serum potassium of & lt;3.5 mEq / L during the period between January 2009 and August 2015 . - pubmed
We studied the incidence , etiology , clinical profile , and acid - base disturbances in patients presenting with hypokalemic paralysis and analyzed the significance of periodic and non - periodic forms of hypokalemic paralysis on patient 's outcome . - pubmed
Eighty - one ( 39 % ) patients had metabolic acidosis , 78 ( 38 % ) had normal acid - base status , and 47 ( 23 % ) patients had metabolic alkalosis . - pubmed
Patients with non - periodic paralysis had more urinary loss ( 40.1 vs. 12.2 mmol , P = 0.04 ) , more requirement of potassium replacement ( 120 vs. 48 mmol , P = 0.05 ) , and longer recovery time of weakness ( 48.1 vs. 16.5 h , P = 0.05 ) than patients with periodic paralysis . - pubmed
Patients with periodic paralysis had significant incidence of rebound hyperkalemia . - pubmed
Propranolol eye drops in patients with corneal neovascularization . - pubmed
RATIONALE : Studies performed in animal models of corneal neovascularization suggested the possible efficacy of a treatment with propranolol . - pubmed
PATIENT CONCERNS : Two patients with corneal neovascularization complicating the Stevens - Johnson syndrome , not responsive to steroids and cyclosporine , were treated with propranolol eye drops . - pubmed
OUTCOMES : Both patients reported dramatic subjective benefits ( reduction of photophobia and discomfort ) without adverse effects , and in the patient with a less advanced disease , an objective reduction of neovascularization and an improved visual acuity was observed . - pubmed
Loss of skeletal muscle mass and its predictors in type 2 diabetes patients under a multifaceted treatment approach . - pubmed
Methods : For 6 months we observed the changes in the body compositions of 72 Japanese patients with type 2 diabetes who underwent multifaceted treatment including educational hospitalization . - pubmed
Conclusions : Baseline accumulation of visceral fat may predict a preferential reduction of visceral fat rather than skeletal muscle during weight control programs in type 2 diabetes patients . - pubmed
Animal models of radiation retinopathy could provide means to identify effective therapies . - pubmed
Here , we review the literature for all animal models of radiation retinopathy , summarize anatomical highlights pertaining to animal models , identify additional physiological factors to consider when investigating radiation retinopathy , and explore the use of clinically relevant tests for studying in vivo models of radiation retinopathy . - pubmed
Testing for EBV is an investigation required at baseline in acute hepatitis and physicians should carefully evaluate serological results , including those for viral and autoimmune hepatitis that may be falsely positive in infectious mononucleosis . - pubmed
Previous studies in humans have indicated that de novo lipogenesis contributes considerably to redundant lipid storage and steatosis in the liver of patients with nonalcoholic fatty liver disease ( NAFLD ) , and then more severe complications occur . - pubmed
However , the molecular mechanism by which EA attenuates hepatic steatosis in individuals with undesirable hepatic genetic alterations remains rarely studied . - pubmed
Human hepatoma cell lines were used for mechanical validation in vitro . - pubmed
MATERIALS AND METHODS : Thirty - seven children with Hodgkin lymphoma underwent 1.5 - tesla ( T ) whole - body MRI using short tau inversion recovery ( STIR ) half - Fourier - acquisition single - shot turbo - spin - echo and diffusion - weighted imaging ( DWI ) . - pubmed
Patients with end - stage renal disease ( ESRD ) whether on dialysis therapy ( DTDT ) or received a kidney transplant ( KT ) have previously shown unfavorable surgical outcomes . - pubmed
WES has the potential to provide a rapid and more accurate genetic diagnosis in ARA , which is crucial for the treatment of the patients . - pubmed
Transcriptome and physiology analysis identify key metabolic changes in the liver of the large yellow croaker ( Larimichthys crocea ) in response to acute hypoxia . - pubmed
However , hypoxia stress become a major obstacle to the benign development of L. - pubmed
To understand the energy metabolism mechanism adapted to hypoxia , we analyzed the transcriptome and physiology of L. - pubmed
This study increases our understanding of the energy metabolism mechanism of the hypoxia response in fish and provides a useful resource for L. - pubmed
Infection caused by Borrelia burgdorferi can occur throughout Poland and therefore , according to ECDC description , the whole country should be considered as an endemic area . - pubmed
About 60 % of patients with multiple warts showed complete clearance of distant untreated warts . - pubmed
Vascular aging is an important physiological and pathological basis for the aging of organs and systems of the human body and is the common pathogenesis of various chronic diseases in the elderly . - pubmed
Importance Chlamydia trachomatis is an obligate intracellular pathogen , causing sexually transmitted diseases and trachoma . - pubmed
Maxillary constriction is a common skeletal craniofacial abnormality , and transverse maxillary deficiency affects 30 % of patients receiving orthodontic and surgical treatment . - pubmed
The study group consisted of 36 patients ( 16 women ) aged 17 to 42 years ( M = 27.1 ; SD = 7.8 ) with a known complete skeletal crossbite and who underwent transpalatal distraction procedure . - pubmed
( 2)Univariate analysis showed that patients with grade III - IV acute graft - versus - host disease ( aGVHD ) or hematopoietic cell transplantation comorbidity index ( HCT - CI ) > = 2 points or patients in very high - risk group of the Revised International Prognostic Scoring System ( IPSS - R ) had significantly decreased OS [ ( 42.9 + -13.2 ) % vs ( 72.9 + -4.2 ) % , chi(2)=8.620 , P=0.003 ; ( 53.3 + -7.6 ) % vs ( 72.6 + -4.7 ) % , chi(2)=6.681 , P=0.010 ; ( 53.8 + -6.8 ) % vs ( 76.6 + -6.2 ) % vs ( 73.3 + -7.7 ) % , chi(2)=6.337 , P=0.042 ] . - pubmed
Detection of multidrug - resistant strains of Salmonella in poultry farms suggests the need for detailed epidemiological and molecular studies to establish sources of acquisition of resistant Salmonella strains . - pubmed
Optimized Protocol to Generate Spinal Motor Neuron Cells from Induced Pluripotent Stem Cells from Charcot Marie Tooth Patients . - pubmed
Although several protocols are available to differentiate hiPSCs into neurons , their efficiency is still poor for CMT patients . - pubmed
Thus , our goal was to develop a robust , easy , and reproducible protocol to obtain MNs from CMT patient hiPSCs . - pubmed
This method of generating MNs from CMT patients in vitro shows promise for the further development of assays to understand the pathological mechanisms of CMT and for drug screening . - pubmed
PURPOSE : This study aimed to explore the incidence rate of delirium and to determine the risk factors among critically ill older patients . - pubmed
Streptococcus pneumoniae is one of the leading causes of death worldwide . - pubmed
INTRODUCTION : Preclinical data demonstrate the potential for exercise training to protect against anthracycline - related cardiotoxicity , but this remains to be shown in humans . - pubmed
Korea had been one of hyperendemic countries of human parasitic infections until 1970s . - pubmed
Using a humanized lupus mouse model , we showed that the transfer of Th17 cell - depleted PBMCs from lupus patients resulted in a significantly reduced plasma cell response and attenuated renal damage in recipient mice compared to the transfer of total SLE PBMCs . - pubmed
CONCLUSIONS : Although larger studies are needed to confirm these results , our data open up new ways of investigation into the effects of AIs on QoL in HR+ BC patients . - pubmed
Thus , we report the development of valuable animal models of osteopetrosis , and our results shed light on drug development for antiosteopetrosis therapy . - pubmed
Therefore , in vivo analyses were performed following ischemia in normal , ischemic , and AY9944 - treated animal groups . - pubmed
Among 23 isolates of Neisseria meningitidis tested , which included representatives of sero - groups A , B , C , D , X , Y , and Z , only one strain in group X gave a false - positive reaction . - pubmed
Bluetongue in cattle : effects of vector - transmitted bluetongue virus on calves previously infected in utero . - pubmed
Three of 7 principal calves , after a challenge of immunity exposure by bites of bluetongue ( BT ) virus - infected Culicoides variipennis , became latently infected with BT virus . - pubmed
These calves were born to heifers infected with the homologous virus by bites of C variipennis at 60 or 120 days ' gestation . - pubmed
A study of repeat myelograms carried out in 93 patients revealed that the incidence of thecal scarring following Conray lumbar radiculography is high ( 61 % of all cases ) , and only slightly lower than that found after Myodil myelography ( 74 % ) . - pubmed
Patients at risk for other reasons carrying residual stones after cholecystectomy , or suffering from stenosis of the papilla , or harboring stones in the choledochus after choledochoduodenostomy should be subjected to endoscopic papillotomy . - pubmed
Patients at risk for other reasons suffering from cholecystolithiasis or choledocholithiasis should be subjected at first to endoscopic papillotomy , and only thereafter to cholecystectomy . - pubmed
Eight male patients with cystic fibrosis , normal nutrition , normal physical activity , relatively mild pulmonary disease , no evidence of liver disease and no family history of diabetes mellitus underwent a series of carbohydrate tolerance tests in comparison with a group of 18 normal male subjects matched for age and body weight . - pubmed
Bladder neuropathy and gastric paralysis in polyarteritis nodosa associated with hepatitis B virus . - pubmed
Inhibition of aminophylline - induced convulsions in mice by antiepileptic drugs and other agents . - pubmed
)-induced convulsions in mice . - pubmed
Valproate at 500 mg / kg protected fewer than 50 % of mice against the clonic phase . - pubmed
Four treatment regimens for patients with specified combinations of low back pain and sciatica were evaluated . - pubmed
Traction , for patients with low back pain and sciatica , and epidural injections when a root palsy was present also produced some significant pain relief . - pubmed
The results of these studies suggest that the pathogenesis of tissue invasion and hemorrhagic tissue necrosis observed in P. - pubmed
Ten patients recovered uneventfully and ten developed a major infection , three of whom died . - pubmed
[ Severe pneumopathy caused by Pneumocystis carinii in chickenpox in a immunosuppressed adult ] . - pubmed
This would discard duct obliteration as a procedure suitable for pancreas transplantation , since optimal endocrine pancreas function is the aim of pancreas transplantation in patients suffering from type - I diabetes mellitus . - pubmed
To evaluate the appropriate dosage of polyestradiol phosphate ( PEP , Estradurin ) as single - drug therapy , patients with metastatic prostatic carcinoma were given 80 , 160 or 240 mg PEP every 4 weeks for at least 6 months . - pubmed
We evaluated the pulmonary status of 18 children 7 to 8 years after their hospitalization for chlamydial pneumonia of infancy . - pubmed
Effects of muramyl dipeptide and trehalose dimycolate on resistance of mice to Toxoplasma gondii and Acanthamoeba culbertsoni infections . - pubmed
The effects of synthetic muramyl dipeptide ( MDP ) and natural trehalose dimycolate ( TDM ) against parasitic infections by intracellular Toxoplasma gondii and free - living Acanthamoeba culbertsoni were studied . - pubmed
Partial protection against lethal intranasal A. culbertsoni infection was conferred by specific immunization with viable trophozoites of nonpathogenic Acanthamoeba lugdunensis . - pubmed
Wild - type Gross leukemia virus and heritable autoimmune disease of New Zealand mice . - pubmed
This report provides a background to biochemical investigations on human glycerol kinase deficiency , an inborn error of metabolism which may be characterized by adrenal hypoplasia and insufficiency . - pubmed
Subjects were 50 patients fulfilling DSM - III criteria for schizophrenic disorder who had been successfully maintained with 25 mg or less of fluphenazine decanoate . - pubmed
We present the clinical case of a female patient with cirrhosis of the liver . - pubmed
The benefits in patient management are discussed and particular note is made of this technique for female patients with chronic urinary retention and overflow incontinence . - pubmed
Computed tomography of the pulmonary hilum in patients with bronchogenic carcinoma . - pubmed
In 30 patients with histologically proven bronchogenic carcinoma , computed tomographic ( CT ) scans of the pulmonary hila , plain radiographs , and medical records were reviewed . - pubmed
The frequencies of recovered disomy among the meiotic segregants of yeast ( Saccharomyces cerevisiae ) triploids were assessed under conditions in which all 17 yeast chromosomes were monitored simultaneously . - pubmed
Ten hypertensive ( hyper ) and hypotensive ( hypo ) turkeys of both sexes were used to evaluate the effect of various stimuli on blood pressure ( BP ) and heart rate ( HR ) . - pubmed
The effects of various doses and the time of injection have been measured quantitatively in four transplantable rodent tumours . - pubmed
Neonatal rats were subjected to transient cerebral hypoxic - ischemia ( unilateral occlusion of the common carotid artery + 7.70 % O2 for 100 min ) and allowed to recover for 3 h , 24 h , 2 days or 14 days . - pubmed
METHODS : We studied 30 subjectively asymptomatic patients aged 8 to 25 years treated for pediatric malignancies with chest irradiation ( XRT ) + /- chemotherapy . - pubmed
METHODS : A retrospective , computer - aided search identified 442 consecutively registered patients with malignant melanoma at the Cutaneous Oncology Program . - pubmed
All patients had stage 1 or 2 disease ( cutaneous disease only ) at diagnosis . - pubmed
We describe a young woman with a concomitant infection of C. - pubmed
From 1973 to 1991 , 13 patients [ 4 females ( 30 % ) and 9 males ( 70 % ) ] were diagnosed with adrenal carcinoma at our hospital . - pubmed
Eleven patients ( 85 % ) presented with abdominal symptoms and 8 ( 61 % ) with paraneoplastic syndrome . - pubmed
On follow - up , 10 thrombotic episodes occurred in 10 patients , 8 of whom were receiving anticoagulant therapy . - pubmed
Derivative ( 11)t(7;11)(q11;q24 ) in a child with acute megakaryoblastic leukemia . - pubmed
We document the clinical , morphologic , and cytogenetic findings in a 2 1/2 - year - old patient with acute megakaryoblastic leukemia . - pubmed
CONCLUSIONS : The results further high - light the differences between patients with primary progressive and those with relapsing remitting / secondary progressive multiple sclerosis . - pubmed
Overall survival was lower for patients with glandular carcinomas than for those with squamous cell carcinomas ( 26 % vs. 55 % , P = 0.09 ) . - pubmed
This difference was almost entirely due to increased mortality in patients with Stage Ib adenocarcinomas ( 53 % vs. 88 % for squamous cell carcinoma , Stage Ib , P = 0.03 ) . - pubmed
CONCLUSIONS : The major prognostic markers for cervical cancer survival in this high risk patient population were clinical stage and histology , factors identical to those identified for other populations . - pubmed
The present study was performed to determine the site of aromatization in human breast cancers , using both immunocytochemistry and in situ hybridization . - pubmed
The efficacy of single - dose aprotinin 2 million KIU in reducing blood loss and its impact on the incidence of deep venous thrombosis in patients undergoing total hip replacement surgery . - pubmed
STUDY OBJECTIVE : To evaluate the efficacy of a 2 million KIU single dose of aprotinin on blood loss , transfusion requirements , and incidence of deep venous thrombosis ( DVT ) in patients undergoing total hip replacement surgery . - pubmed
On the seventh postoperative day , all patients in both groups underwent venography to ascertain the incidence of DVT . - pubmed
Infection of erythrocytes with mature asexual stages of P. - pubmed
[ Proliferation of T - cells , macrophages , neutrophilic granulocytes and fibroblast - like cells in the synovial membrane of patients with rheumatoid arthritis ] . - pubmed
Neurologic findings in coronary artery bypass patients : perioperative or preexisting ? - pubmed
OBJECTIVES / DESIGN : This prospective study compares the incidence of preexisting neurologic findings in elective cardiac surgery patients presenting with and without coronary atherosclerosis . - pubmed
MEASUREMENTS AND MAIN RESULTS : The patients , 9 of 24 of whom were female , were aged 46 to 78 years and , other than ischemic heart disease , had medical histories that were similar between groups , with the exception of one patient having scleroderma . - pubmed
Nine percent ( 1 of 11 ) of the valve - only patients showed subtle preoperative neurologic abnormalities , compared with 89 % ( eight of nine ) of the valve patients having concomitant coronary surgery and 100 % ( four of four ) of coronary artery bypass - only patients . - pubmed
CONCLUSION : This survey shows that both subtle neurological abnormalities and magnetic resonance imaging lesions can be found in a high percentage of patients with coronary atherosclerosis . - pubmed
Malignant colonic neoplasia in cats : 46 cases ( 1990 - 1996 ) . - pubmed
OBJECTIVE : To evaluate a group of cats with malignant colonic neoplasia and to identify factors related to survival time . - pubmed
ANIMALS : 46 cats with malignant colonic neoplasia . - pubmed
A diagnosis of malignant colonic neoplasia had been established by histologic examination of endoscopic biopsy specimens ( 3 cats ) , biopsy specimens obtained during laparotomy ( 38 ) , or necropsy specimens ( 5 ) . - pubmed
Histopathologic diagnoses included adenocarcinoma ( 21 cats ) , lymphoma ( 19 ) , mast cell tumor ( 4 ) , and neuroendocrine carcinoma ( 2 ) . - pubmed
CLINICAL IMPLICATIONS : Obtaining clean margins at surgery seems to increase survival time in cats with malignant colonic neoplasia . - pubmed
Data from this study indicate that the survival time of certain cats with colonic lymphoma may not be affected by chemotherapy . - pubmed
Cats with colonic adenocarcinoma should receive a subtotal colectomy with consideration of doxorubicin administration to increase survival time . - pubmed
Clinical efficacy of lactulose in cirrhotic patients with and without subclinical hepatic encephalopathy . - pubmed
Seventy - five cirrhotic patients with hyperammonemia in the past or at the time of the study were randomly divided into two groups ( treated with lactulose or nontreated ) in 14 hospitals in Japan . - pubmed
Thirty - six cirrhotic patients were diagnosed as having subclinical hepatic encephalopathy ( SHE ) , and 39 were diagnosed as non - SHE . - pubmed
We concluded that lactulose treatment in cirrhotic patients with SHE is effective with respect to psychometric tests . - pubmed
The drugs undergo extensive hepatic metabolism ; dosage adjustments should be considered for patients with hepatic dysfunction . - pubmed
To elucidate the conditions of atrophy in the sternocleidomastoid muscle ( SCM ) after modified neck dissection ( MND ) , we tried to scrutinize the atrophic regions in the SCM and determine the cause of atrophy , by electromyography in 40 patients with SCM atrophy following MND . - pubmed
Atrophy was observed in the caudal portion in the SCM in 90 % of the patients . - pubmed
Electromyographic examination revealed neurogenic atrophy in 24 patients , ischemic atrophy in 11 , and a mixing of both types in 5 . - pubmed
BACKGROUND AND PURPOSE : We sought to determine the incidence of recurrent carotid stenosis in patients in the Asymptomatic Carotid Atherosclerosis Study ( ACAS ) who had undergone carotid endarterectomy and were prospectively followed with Doppler ultrasound for up to 5 years . - pubmed
Of the 136 patients judged to have recurrent stenosis , only 8 ( 5.9 % ) underwent reoperation ( only 1 for symptoms ) . - pubmed
cereus strains in concentrated whey were 100 % similar to the type strain in 16S rDNA sequence ( 500 bp ) although they were not or only poorly recognized as B. - pubmed
When studies identifying patients with fracture , rather than numbers of fractures were pooled , the magnitude of effect was less ( RR 0.74 ; 95 % CI 0.60 - 0.93 ) , and the separate effects on vertebral and non - vertebral fractures was of borderline significance . - pubmed
PURPOSE : To evaluate the role of computed tomography in patients with dacryostenosis . - pubmed
OBJECTIVES : To compare the ultrasonographic ( US ) appearances of the oral mucosa in health with patients with systemic sclerosis ( SSc ) . - pubmed
METHODS : An innovative 20 MHz US scanner was used to examine the lips , cheeks and oral vestibule of ten healthy persons and ten patients with SSc . - pubmed
The clinical , US and histopathological features of one patient with a fibro - epithelial polyp of the buccal mucosa are reported in detail . - pubmed
RESULTS : Two patients with SSc displayed increased echogenicity due to fibrotic deposits . - pubmed
Staphylococcus aureus pneumonia , hyponatremia , hypertension , proteinuria , and hematuria in a 14 - year - old boy . - pubmed
PARTICIPANTS : Five refractive surgeons and 29,916 eyes that underwent surgical correction of ametropia ( 83.2 % were myopic ) ranging from -0.75 to -29.00 diopters ( D ; mean : -6.19 D ) and from +1.00 to +6.00 D ( mean : +3.23 D ) participated in this retrospective study . - pubmed
It is very important to inform patients that LASIK only corrects the refractive aspect of myopia . - pubmed
We employed three strains of H. - pubmed
The progression of muscular weakness of patients suffering from muscular dystrophies directly correlates with the progressive loss of myofibers , accompanied by fibrosis . - pubmed
No systematic data are available for patients with different kidney diseases . - pubmed
We report the case of a patient with a pseudoaneurysm of the ascending aortic clinically diagnosed 5 months after surgical replacement of the aortic valve . - pubmed
METHODS : Forty - six patients suspected of having moyamoya disease were examined with high - resolution turbo MR angiography with the ZFI technique , MRI , and conventional angiography . - pubmed
Moyamoya disease was diagnosed in 42 of these patients . - pubmed
Fifteen patients had persistent AF ( & gt ; or = 6 months ) , and the remaining 15 patients had no history of AF . - pubmed
Idiotype - based immunotherapy has been explored in myeloma patients with disappointing results . - pubmed
The importance of routine screening for microalbuminuria in patients with diabetes has gained widespread acceptance . - pubmed
A patient undergoing excision of phaeochromocytoma developed refractory hypotension which was complicated by significant intraoperative blood loss . - pubmed
All three studies demonstrated a significant survival benefit for bladder cancer patients receiving adjuvant combination therapy . - pubmed
OBJECTIVES : To present the unique case of a patient who sustained an ipsilateral and contralateral injury after external laryngeal trauma . - pubmed
METHODS : A case report is presented of a patient who sustained both an ipsilateral and a contralateral injury after blunt laryngeal trauma . - pubmed
METHODS : Normal Sprague - Dawley rats rendered diabetic by a single injection of streptozotocin ( 50 mg / kg ) were treated with either aminoguanidine , ramipril or standard water . - pubmed
A diagnosis of syndrome of inappropriate secretion of antidiuretic hormone ( SIADH ) was mentioned in eight patients , sometimes without checking their urinary electrolytes or osmolality . - pubmed
RESULTS : No perioperative mortality was seen , and 5 % of the patients had minor infections of the wound , not resulting in loss of the bypass , the limb , or life . - pubmed
We analyzed gene expression in various rat conditions to identify novel candidate genes for schizophrenia . - pubmed
METHODS : A clinical sequential trial was designed and the biosynthetic bone and the patient 's ilium were respectively used in the treatment of femoral nonunions and interbody fusion . - pubmed
[ Collective dietary toxi - infection by means of Salmonella of probable South - American origin ( Salmonella bredeney ) ] . - pubmed
Blood pressure , cholesterol content of serum and tissues and atherogenesis in the rat . - pubmed
Rats with high serum lipide concentrations developed intimal lesions similar to those of human atherosclerosis . - pubmed
On the other hand , rats receiving desoxycorticosterone acetate without salt or salt without desoxycorticosterone acetate did not show any intensification of hypercholesterolemia or hyperlipemia . - pubmed
It remained uncertain whether the increase in atherosclerosis in the hypertensive animals was dependent on the increased lipide content of serum and tissues or on a local effect of the elevated blood pressure . - pubmed
RESULTS : Six out of 11 patients with unilateral positive biopsy specimens were diagnosed as unilateral cancer , and 9 of 10 patients with bilateral positive biopsy specimens were diagnosed as bilateral cancer on MRI . - pubmed
A nested PCR technique was performed to detect a specific 483 bp DNA fragment of Orientia tsutsugamushi , the aetiological agent of scrub typhus , in 53 blood samples from 36 patients with acute pyrexia of unknown origin in southern Thailand . - pubmed
The specific primers could amplify the specific DNA from all 10 prototype strains of O. - pubmed
Thus , nested PCR may be more sensitive than the serological test for diagnosis of scrub typhus and prolonged persistence of O. - pubmed
According to examination of 97 patients with vascular vertigo the dependence on vertigo to vertebral spondylosis and insufficiency vertebro - basilar artery was showed . - pubmed
Vertebral degeneration was noticed in 70.1 % , basilar artery insufficiency in 42.3 % of the patients . - pubmed
Rotary test showed labyrinth asymmetry in 41.2 % and in caloric test 50.5 % of the patients . - pubmed
Rio Meta strain of Plasmodium vivax in New World monkeys and anopheline mosquitoes . - pubmed
An archived strain of Plasmodium vivax , isolated from Rio Meta , northern Colombia , in 1972 was adapted to grow in splenectomized Aotus lemurinus griseimembra and A. - pubmed
Effect of gemfibrozil on change in renal function in men with moderate chronic renal insufficiency and coronary disease . - pubmed
We conducted this study to determine whether gemfibrozil reduced rates of renal function loss in people with moderate CRI . - pubmed
METHOD : 350 opiate - dependent patients were examined at yearly follow - ups over 4 years using the EuropASI for the assessment of drug - related problems and the CIDI for diagnostic of psychiatric disorders . - pubmed
The paper presents a case of 64 years old man with infective endocarditis of the mitral valve , complicated with a development of mycotic aneurysm of the right coronary artery , who was successfully surgically treated . - pubmed
We report that genetic elimination of mature T and B lymphocytes in a transgenic mouse model of inflammation - associated de novo epithelial carcinogenesis , e.g. - pubmed
, K14 - HPV16 mice , limits neoplastic progression to development of epithelial hyperplasias that fail to recruit innate immune cells . - pubmed
Adoptive transfer of B lymphocytes or serum from HPV16 mice into T and B cell - deficient / HPV16 mice restores innate immune cell infiltration into premalignant tissue and reinstates necessary parameters for full malignancy , e.g. - pubmed
Mitochondrial behaviour in the early stages of ROS stress leading to cell death in Arabidopsis thaliana . - pubmed
RESULTS : 193 ESSCLC patients were identified . - pubmed
However in a double - blind , randomized , placebo - controlled trial with more carefully selected patients , there was no significant difference between recurrence rates with 650 or 1300 mg MgO daily and the placebo . - pubmed
The failure of MgO and Mg ( OH ) 2 as sole therapy may be related to poor absorption and low rates of Mg deficiency in the patient populations tested . - pubmed
CONCLUSIONS : Clinical trial evidence does not justify the use of MgO or Mg ( OH ) 2 as a sole therapy for calcium oxalate kidney stones in a general patient population . - pubmed
Clinical trials should focus on patients who are likely to be Mg deficient . - pubmed
Human pulmonary dirofilariasis : a case report and review of the recent Japanese literature . - pubmed
Human pulmonary dirofilariasis is a rare zoonotic infection caused by the dog heartworm Dirofilaria immitis , which is transmitted via a vector / intermediate host , generally the mosquito . - pubmed
The authors present a case of histologically diagnosed human pulmonary dirofilariasis , in which the lesion was resected using video - assisted thoracic surgery ( VATS ) . - pubmed
Of these 24 patients with human pulmonary dirofilariasis , 12 ( 50 % ) were men ( mean age 54 years , range 29 - 80 years ) and 67 % were asymptomatic . - pubmed
OBJECTIVE : To compare the effects of daily ingestion of soy flour ( S ) , ground flaxseed ( F ) , or wheat flour ( W ) muffins , on quality of life and hot flash frequency and severity in postmenopausal women . - pubmed
I. Cytotoxic cells with specificity for mouse Moloney leukemia cells . - pubmed
Molecular characterization of human adenomyosis . - pubmed
METHODS : Forty Wistar rats were randomly assigned to a control group and an asthma group ( 20 in each group ) . - pubmed
There have been no treatment advances for alcoholic liver disease but , on balance , steroids are still favored for carefully selected patients with alcoholic hepatitis . - pubmed
After having established the mice model of hypnosis and analgesia by intraperitoneally injecting ( i.p . ) - pubmed
Heparin and low molecular weight heparin ( LMWH ) are widely used for treatment of cancer patients with thrombosis , a common complication of malignant disease . - pubmed
Several recent prospective clinical studies indicate that heparin might improve outcomes of human cancer . - pubmed
Meanwhile , experimental evidence from mouse models consistently demonstrates that heparin efficiently inhibits metastasis . - pubmed
The use of clinically acceptable amounts of heparin did not further aff5ct metastasis rates in such mice . - pubmed
Energy homeostasis in mammals is achieved through tight regulation of tissue - specific metabolic pathways that become dysregulated in metabolic diseases including diabetes and obesity . - pubmed
The actual knowledge of HNE reactivity , metabolism , signaling and modulatory effect in the various human organs should provide a solid background to the investigation of the aldehyde 's contribution to the pathogenesis of human major chronic diseases and would likely promote advanced and oriented applications not only in diagnosis and prevention but also in molecular treatment of human diseases . - pubmed
We have treated 30 POEMS patients with ASCT at Mayo Clinic , Rochester . - pubmed
During transplant period , patients had high rates of fever , diarrhea , weight gain and rash ( 93 % , 77 % , 53 % and 43 % , respectively ) . - pubmed
Depending on the definition used , approximately 50 % of patients satisfied criteria for engraftment syndrome . - pubmed
Patients and methods Seven patients were treated neurosurgically with laminectomy and abscess drainage for spinal epidural abscesses from 1991 to 1994 . - pubmed
Results All but one patient had several weeks of local spinal pain ( mainly after minor trauma ) , immunosuppression , and all exhibited excessively high blood sedimentation rates . - pubmed
Since preoperative neuronal damage persisted too long , only 3 patients showed slight improvement of their neurological functions postoperatively . - pubmed
We reviewed 40 Corin Cormet 2000 ( Corin , Cirencester , UK ) metal - on - metal resurfacing hips , in 36 patients , for the presence of femoral neck narrowing . - pubmed
UNLABELLED : We report diagnostic difficulties in the patient with fever of unknown origin . - pubmed
[ Chronic dizziness in elderly people : its clinical characteristics and magneto - encephalographic findings ] . - pubmed
During the last several years , we performed cerebral functional studies using auditory - evoked magneto - encephalography ( MEG ) in elderly people with chronic dizziness . - pubmed
This abnormality is similar to that detected by non - evoked MEG in temporal lobe epilepsy patients . - pubmed
In patients with Type A abnormality , administration of anticonvulsants brought about dramatic improvement of dizziness in association with disappearance of rotational abnormalities . - pubmed
Patients with Type B abnormality commonly have the asymmetry of body , such as left - right imbalance of visual acuity , left - right neck pain , or remarkable scoliosis , in association with insomnia and/or depressive state . - pubmed
In patients with Type A abnormality , dizziness may be caused by abnormal neuronal excitements in left or right HPR center . - pubmed
Pubo - urethral ligament injury causes long - term stress urinary incontinence in female rats : an animal model of the integral theory . - pubmed
No difference was noted when comparing pubo - urethral ligament transection to pudendal nerve transection ( p = 0.76 ) , indicating the long - term durability of pubo - urethral ligament transection on inducing stress urinary incontinence in the female rat . - pubmed
CONCLUSIONS : Our results show that pubo - urethral ligament deficiency in the female rat induces long - term stress urinary incontinence that is comparable to that in the established stress urinary incontinence model via pudendal nerve transection . - pubmed
Our novel rat model could be used to investigate mechanisms of stress urinary incontinence in females , including the role of urethral hypermobility and potential therapeutic interventions for stress urinary incontinence . - pubmed
Ten consecutive patients [ mean ( range ) age 26 ( 18 - 39 ) y ] with active colonic CD ( mean CD activity index : 383.7 + /- 129.8 ) were prospectively included in the study . - pubmed
Sequential defunctionalization followed by thyroxine supplementation as preoperative preparation of hyperthyroid patients undergoing thyroidectomy . - pubmed
BACKGROUND : Preparing hyperthyroid patients for thyroid surgery with a combination of antithyroid drugs and thyroxine has long been controversial because this combination usually results in only partial inhibition of thyroid function . - pubmed
METHODS : Four hundred and seventy - one hyperthyroid patients seen at our hospital were divided into experimental and control groups . - pubmed
CONCLUSIONS : Sequential thyroid defunctionalization followed by thyroxine supplementation is effective in reducing the bleeding volume and postoperative complication rate in selected hyperthyroid patients undergoing thyroidectomy . - pubmed
In support of these observations , we report the occurrence of clinical pneumonitis in 3 patients in association with everolimus therapy after heart transplantation in the absence of other causative factors . - pubmed
Sepsis resulting from Enterobacter aerogenes resistant to carbapenems after liver transplantation . - pubmed
BACKGROUND : Sepsis due to Enterobacter aerogenes ( E. - pubmed
RESULTS : A 39 - year - old man had a biliary fistula and then was found to have multiple liver abscesses through abdominal ultrasound and an abdominal computed tomography scan , and carbapenem - sensitive E. - pubmed
CONCLUSIONS : We first report an unusual case of sepsis caused by E. - pubmed
BACKGROUND : Novel therapies are necessary to improve outcomes for patients with squamous cell carcinomas ( SCC ) of the head and neck . - pubmed
Historically , vaccinia virus was administered widely to humans as a vaccine and led to the eradication of smallpox . - pubmed
At a multiplicity of infection ( MOI ) of 1 , GLV-1h68 was highly cytotoxic to the four cell lines , resulting in & gt ; or = 90 % cytotoxicity over 6 days , and the remaining two cell lines exhibited & gt;45 % cytotoxicity . - pubmed
CONCLUSION : These results demonstrate significant oncolytic efficacy by an attenuated vaccinia virus for infecting and lysing head and neck SCC both in vitro and in vivo , and support its continued investigation in future clinical trials . - pubmed
CONCLUSIONS : In this patient - level pooled analysis , overall use of SES compared with BMS demonstrated persistent superior efficacy at 5 years in terms of a reduction in target vessel revascularization , without an increase in rates of death , MI , or stent thrombosis . - pubmed
( The Initial Double - Blind Drug - Eluting Stent vs Bare - Metal Stent Study , NCT00233805 ; The Study of the BX Velocity Stent in the Treatment of De Novo Artery Lesions , NCT00381420 ; Study of Sirolimus - Coated BX VELOCITY Balloon - Expandable Stent in Treatment of de Novo Native Coronary Artery Lesions [ SIRIUS ] , NCT00232765 ; The Study of the BX VELOCITY Stent In Patients With De Novo Coronary Artery Lesions , NCT00235144 ) . - pubmed
METHODS : We compared change in category ( animal and supermarket ) and letter ( F , A , S ) fluency among 239 participants in 3 groups : remained cognitively normal throughout follow - up ( n = 96 ) , developed Alzheimer ' s Disease ( AD ; preclinical AD , n = 21 ) , and with AD at initial testing ( prevalent AD , n = 122 ) . - pubmed
RESULTS : At baseline , prevalent and preclinical AD groups scored lower on animal than letter fluency . - pubmed
Overall , animal fluency declined faster than letter fluency ; animal fluency declined significantly faster than letter fluency among cognitively normal and prevalent AD participants . - pubmed
Steeper declines on both fluency measures distinguish preclinical AD from cognitively unimpaired individuals . - pubmed
Role of wearable and automatic external defibrillators in improving survival in patients at risk for sudden cardiac death . - pubmed
Both devices have been shown in small series to be highly effective at restoring sinus rhythm in patients with a ventricular tachyarrhythmia . - pubmed
In order to evaluate the in vivo antioxidation activity , the serum metabolites of emodin following intravenous and oral administrations were prepared from rats and characterized , followed by investigating the effects on 2,2 '- azobis ( 2 - amidinopropane hydrochloride )-induced hemolysis . - pubmed
METHODS : Detailed data regarding mortality were available on all patients undergoing aortic valve replacement for isolated aortic stenosis during a 5 - year period in the southeast region of Sweden ( n=396 ) . - pubmed
Multiple sclerosis ( MS ) is a devastating neurological condition that mainly affects young adults and is associated with long - standing morbidity . - pubmed
Most research efforts to date have concentrated on the mechanisms of immune - mediated demyelination , whereas mechanisms of axonal injury , the major determinant of neurological deficits in MS patients , have been elusive beyond observational analyses . - pubmed
This review discusses current understanding of the pathology and novel clinical investigations of axonal injury in MS and the commonly used MS animal model , experimental autoimmune encephalomyelitis . - pubmed
Occupational allergy to bell pepper pollen in greenhouses in the Netherlands , an 8 - year follow - up study . - pubmed
BACKGROUND : Pollen from bell pepper plants cultivated in greenhouses are known to cause occupational allergic disease . - pubmed
A cross - sectional study among 472 bell pepper employees in 1999 estimated prevalences for sensitization to bell pepper pollen of 28 % and for work - related allergic symptoms of 54 % . - pubmed
During the 8 - year follow - up , the cumulative incidence of sensitization to bell pepper pollen was 9 % and of work - related rhinitis 19 % . - pubmed
CONCLUSION : Cumulative incidences for sensitization to bell pepper pollen , work - related rhinitis and asthma symptoms were 9 % , 19 % and 8 % , respectively . - pubmed
PURPOSE : The objective of the present study was to emphasise the oral and dental findings of a male patient with the Maroteaux - Lamy syndrome who successfully underwent bone marrow transplantation ( BMT ) at the age of 22 months . - pubmed
BMT is a therapeutic treatment that is given to permanently replace any disorder caused due to the deficiency of enzymes in patients with storage diseases . - pubmed
Bluetongue virus serotype 8 ( BTV-8 ) infection reduces fertility of Dutch dairy cattle and is vertically transmitted to offspring . - pubmed
In the present study , we examined the function of resveratrol in protecting human lens epithelial B-3 ( HLEB-3 ) cells against H ( 2 ) O ( 2 ) induced cell death and cell apoptosis , its role in reducing H ( 2 ) O ( 2 ) induced intracellular reactive oxygen species ( ROS ) accumulation , and investigated the mechanism by which resveratrol underlies the effect . - pubmed
An 83 - year - old female patient received video - assisted cardiac surgery for excision of a left atrial tumor . - pubmed
The patient was satisfied by the cosmetic healing of the wound and was discharged eight days after the surgery . - pubmed
We report a case of a patient who incurred spontaneous anterior dislocation of a mature cataract which required prompt surgical removal . - pubmed
METHODS : Sixty patients with chronic otitis media of the mucosal type , with pars tensa perforations , were included in the study . - pubmed
Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis . - pubmed
BACKGROUND : Multiple Sclerosis ( MS ) is an acquired inflammatory demyelinating disorder of the central nervous system ( CNS ) and is the leading cause of nontraumatic disability among young adults . - pubmed
In this study , we have examined the effect of oral administration of KATP channel opener diazoxide on induced experimental autoimmune encephalomyelitis ( EAE ) , a mouse model of MS . - pubmed
Mice were orally treated daily with diazoxide or vehicle for 15 days from the day of EAE symptom onset . - pubmed
Oral treatment of mice with diazoxide ameliorated EAE clinical signs but did not prevent disease . - pubmed
In vivo , B16F10 melanoma bearing mice seem not to be responsive to liposomal treatments of natural compounds . - pubmed
Our analysis also suggested a higher miR-146a expression in OSCC tissues of patients carrying C polymorphism . - pubmed
The present study concluded a higher prevalence of the pre - mir-146a C - variant was associated with OSCC progression in patients with this disease . - pubmed
Vitamin D analogs are used for treatment of secondary hyperparathyroidism in patients with chronic kidney disease in order to prevent renal osteodystrophy , bone fracture and pain . - pubmed
Therefore , in everyday clinical practice , hypercalcemia and hyperphosphatemia often limits the ability to suppress secondary hyperparathyroidism in patients with chronic kidney disease . - pubmed
The present thesis describes the first comparative study of alfacalcidol and paricalcitol and their ability to control the disturbances in the mineral metabolism in hemodialysis patients . - pubmed
While free radicals and inflammation constitute major routes of neuronal injury occurring in amyotrophic lateral sclerosis ( ALS ) , neither antioxidants nor non - steroidal anti - inflammatory drugs have shown significant efficacy in human clinical trials . - pubmed
RATIONALE : In clinical trials , homogeneous emphysema patients have responded well to upper lobe volume reduction but not lower lobe volume reduction . - pubmed
RESULTS : Patients with homogeneous emphysema received either upper or lower lobe volume reduction therapy based on findings of radionucleotide scintigraphy scanning . - pubmed
A 57 - year - old man presented a skin lesion on the posterior region of the left forearm with extensive necrosis of skin and subcutaneous layer involving the underlying muscle planes , caused by a venous extravasation of heroin that he reports having injected himself . - pubmed
Efficacy of omega-3 fatty acids supplementation in treatment of uremic pruritus in hemodialysis patients : a double - blind randomized controlled trial . - pubmed
In this study , the effects of omega-3 for treatment of pruritus were investigated in hemodialysis patients . - pubmed
At first , 22 hemodialysis patients suffering from pruritus with previous drug resistance were selected . - pubmed
So it seems that Omega-3 fatty acids could be used as an efficient drug for treatment of pruritus in uremic patients . - pubmed
Outcome following decompressive craniectomy for malignant middle cerebral artery infarction in patients older than 70 years old . - pubmed
Recent clinical trials demonstrated that early decompressive craniectomy reduce mortality rates and improves functional outcomes in healthy young patients ( less than 61 years of age ) with a malignant infarction . - pubmed
The purpose of this study was to assess the efficacy of decompressive craniectomy in elderly patients ( older than 70 years of age ) with a malignant MCA infarction . - pubmed
METHODS : Between February 2008 and October 2011 , 131 patients were diagnosed with malignant MCA infarctions . - pubmed
CONCLUSION : Decompressive craniectomy is effective for patients with a malignant MCA infarction regardless of their age . - pubmed
Therefore , factors other than age should be considered and the treatment should be individualized in elderly patients with malignant infarctions . - pubmed
Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy with or without adjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma : meta - analysis of 1,096 patients from 11 randomized controlled trials . - pubmed
Risk ratios of 1.90 ( 95%CI 1.24 - 2.92 ) , 2.67 ( 95%CI 0.64 - 11.1 ) , 1.04 ( 95%CI 0.79 - 1.37 ) , 0.98 ( 95%CI 0.27 - 3.52 ) were found for grade 3 - 4 leukopenia , grade 3 - 4 thrombocytopenia , grade 3 - 4 mucous membrane , and grade 3 - 4 hepatic hematologic and gastrointestinal toxicity , the most significant toxicities for patients . - pubmed
This alleviates concerns about contrast use in patients with thyroid carcinoma interfering with adjuvant radioiodine therapy . - pubmed
Penicillin - induced epileptiform activity elevates focal brain temperature in anesthetized rats . - pubmed
To elucidate a relationship between changes in focal brain temperature and severity of abnormal brain activity , epileptiform discharges and behavioral seizures were induced by Penicillin G in anesthetized rats , and focal brain - temperature was measured . - pubmed
Therefore , we present a typical case of Meniere ' s disease in contrast to a patient with an intralabyrinthine schwannoma and Meniere - like symptoms . - pubmed
OBJECTIVES : The aims of this study were to investigate an alternative pre - treatment method for resin infiltration using 37 % H3PO4 with a brush applicator and to evaluate the penetration effect of the infiltrant for masking the natural white spot lesions ( WSLs ) in human teeth . - pubmed
We describe a woman with extra luminal gastrointestinal stromal tumour of the stomach that mimicked a left hepatic tumour presenting as an abdominal mass . - pubmed
CASE PRESENTATION : A 51 - year - old woman presented with a history of increasing epigastric pain for two - months duration . - pubmed
Mice were subcutaneously inoculated with 1 x 10(6 ) Lewis carcinoma 3LL cells into the dorsum . - pubmed
Further studies are necessary to evaluate the usefulness of this device in the diagnosis of patients with upper respiratory tract disorders . - pubmed
CONTEXT : The natural progression of metabolic abnormalities among patients with inherited autoinflammation is unclear . - pubmed
In the present study hesperetin exhibited a significant cytotoxic effect in human breast carcinoma MCF-7 cells in a concentration- and time - dependent manner without affecting normal ( HMEC ) as well as immortalized normal mammary epithelial cells ( MCF-10A ) . - pubmed
Initially , the patient was managed as ocular type of myasthenia gravis , but after progression to general limb weakness and areflexia , the diagnosis of chronic inflammatory demyelinating polyneuropathy was made . - pubmed
Newer applications are emerging in the detection of left atrial appendage thrombi and quantification of myocardial blood flow and volume in transplant patients . - pubmed
CONCLUSIONS : Maternal exposure to uncoated Ag - NPs during pregnancy impaired spatial cognition in rat offspring . - pubmed
MATERIALS AND METHODS : Prospective non - randomised study of 242 consecutive patients with substernal goiter out of 2258 patients ( 11 % ) who underwent thyroidectomy . - pubmed
Animal models of gastrointestinal and liver diseases . - pubmed
Animal models of visceral pain : pathophysiology , translational relevance , and challenges . - pubmed
Animal models have played a pivotal role in our understanding of the mechanisms underlying the pathophysiology of visceral pain . - pubmed
This review focuses on animal models of visceral pain and their translational relevance . - pubmed
In addition , the challenges of using animal models to develop novel therapeutic approaches to treat visceral pain will be discussed . - pubmed
Staphylococcus aureus bacteraemia is often complicated by metastatic infectious foci . - pubmed
Classification of neurological abnormalities in children with congenital melanocytic naevus syndrome identifies magnetic resonance imaging as the best predictor of clinical outcome . - pubmed
OBJECTIVES : To establish whether routine MRI of the CNS is a clinically relevant investigation in children with multiple CMN ( more than one at birth ) , and to subclassify radiological abnormalities . - pubmed
METHODS : Of 376 patients seen between 1991 and 2013 , 289 fulfilled our criterion for a single screening CNS MRI , which since 2008 has been more than one CMN at birth , independent of size and site of the largest naevus . - pubmed
RESULTS : Twenty - one per cent of children with multiple CMN had an abnormal MRI . - pubmed
Any child with a stepwise change in neurological / developmental symptoms or signs should have an MRI with contrast of the brain and spine to look for new CNS melanoma . - pubmed
We report a 4 months old infant with orbital rhabdomyosarcoma with poor outcome . - pubmed
Call is made for need for more studies to determine appropriate local therapy in infants with rhabdomyosarcoma . - pubmed
Hyperuricemia has an adverse impact on the prognosis of patients with osteosarcoma . - pubmed
Patients with osteosarcoma have poor prognosis and are often at high risk of death . - pubmed
Hyperuricemia had been suggested as a poor prognostic factor of several cancers , but the prognostic role of hyperuricemia in osteosarcoma patients had not been assessed . - pubmed
In the present study , we investigated the prognostic role of hyperuricemia at baseline on the overall survival of patients with osteosarcoma . - pubmed
Sixty osteosarcoma patients with hyperuricemia were matched ( 1:2 ) to 120 osteosarcoma patients without hyperuricemia with similar age and gender . - pubmed
Data from those patients with osteosarcoma were evaluated retrospectively . - pubmed
Kaplan - Meier method showed that patients with hyperuricemia had shorter overall survival compared with those with normouricemia ( P & lt ; 0.0001 , log - rank test ) . - pubmed
In univariate analysis , hyperuricemia was associated with poorer overall survival in osteosarcoma patients ( HR = 2.71 , 95 % CI 1.75 - 4.20 ; P & lt ; 0.0001 ) . - pubmed
In conclusion , hyperuricemia at baseline is associated with poorer overall survival in osteosarcoma patients , and it has an adverse impact on the prognosis of osteosarcoma patients . - pubmed
Incidence and clinical presentation of myocardial ischemia in patients with chronic CAD in Italy : the ISPICA survey study . - pubmed
METHODS : Thirty - six cardiology units located in different geographic areas of Italy enrolled a total of 1475 outpatients ( 73.6 % men and 26.3 % women ; mean age 71 + - 10 and 67 + - 9 years in men and women , respectively ) with a documented diagnosis of chronic CAD . - pubmed
difficile growth and prevented toxin production in a human gut model of CDI . - pubmed
Eight patients in Macintosh group had tongue - lip - dental trauma during intubation , while only 2 patients received upper airway trauma in Airtraq group . - pubmed
The negative effects of overexposure to ultraviolet ( UV ) radiation in humans , including sunburn and light - induced cellular injury , are of increasing public concern . - pubmed
To date , little information is available about its neurotoxicity during early vertebrate development . - pubmed
Our resent study is the first proof - in - principle that miRNA combination can be exploited to fine - tune the replication of HSV-1 to treat human cancers . - pubmed
METHODS : Two - dimensional polyacrylamide gel electrophoresis ( 2DE ) was used to separate the plasma proteins from T2DM patients and healthy control subjects . - pubmed
This area is of interest as it is impacted both in human demyelinating diseases and in the cuprizone model . - pubmed
The use of fractional exhaled nitric oxide is valuable in select asthmatic patients . - pubmed
FeNO can help the physician identify which patients have eosinophilic inflammation and would potentially respond to corticosteroid therapy . - pubmed
FeNO can be used in the initial diagnosis of asthma and aid in stratification of which patients would be steroid responsive but also for assessment of disease severity , response to treatment , and compliance . - pubmed
Tuberculosis , caused by the bacterium Mycobacterium tuberculosis , remains one of the most serious global health problems . - pubmed
Long - term efficacy and safety of fingolimod in Japanese patients with relapsing multiple sclerosis : 3 - year results of the phase 2 extension study . - pubmed
BACKGROUND : The low level of disease activity and manageable safety profile seen with fingolimod versus placebo in a 6 - month , phase 2 , randomized controlled trial in Japanese patients with relapsing multiple sclerosis ( MS ; ClinicalTrials.gov Identifier NCT00537082 ) were maintained in the initial 6 - month observational study extension . - pubmed
In patients who switched to the active treatment , a 79.5 % decrease in annualized relapse rate ( ARR ; from 1.131 before switch to 0.232 6 - months after switch ) was observed in the first 6 months of the extension phase and thereafter remained low until the end of study ( 0.16 - 0.31 across all assessment time points after switch up to end of study ) . - pubmed
These results indicate that fingolimod provides long - term treatment benefit for Japanese patients with relapsing MS . - pubmed
Herein , we present the case of a 39 - year - old female who presented right ptosis on the follow - up of breast cancer after surgery . - pubmed
Patients Ten eyes of 10 patients with retinal hemangioblastoma in Hippel - Lindau disease were included . - pubmed
Flying foxes have been considered to be involved in the transmission of serious infectious diseases to humans . - pubmed
Data were collected by direct interview using a structured questionnaire consisting of the respondent characteristics ( age , sex and occupation ) ; histories of contacts between flying foxes and humans , dogs and other domestic animals ; and knowledge about infectious diseases , mainly rabies , in flying foxes . - pubmed
Murine model of hepatic breast cancer . - pubmed
To date , very few murine models of hepatic breast cancer exist . - pubmed
METHODS : In this study , a novel murine model of liver breast cancer using the MDA - MB-231 cell line is introduced as an experimental ( preclinical ) model . - pubmed
Common features of the murine model were vascular invasion , lung metastasis and peritoneal seeding . - pubmed
CONCLUSIONS : The novel murine model of hepatic breast cancer established in this study provides a tool to be used to investigate mechanisms of hepatic metastasis and to test potential therapeutic interventions . - pubmed
PURPOSE : We examined changes in visual function and ocular and retinal blood flow ( RBF ) among retinitis pigmentosa ( RP ) participants in a randomized controlled trial of electro - stimulation therapies . - pubmed
CONCLUSION : Increased blood flow following electro - stimulation therapies is an objective , physiological change that occurred in addition to visual function improvements in some RP patients . - pubmed
Ultrastructural Features of Neurovascular Units in a Rat Model of Chronic Compressive Spinal Cord Injury . - pubmed
Objective of this study is to assess the ultrastructural features of the neurovascular unit ( NVU ) in a rat model of chronic compressive spinal cord injury , 24 SD rats were divided into two groups : the control group ( n = 12 ) , and the compression group ( n = 12 ) . - pubmed
The small hive beetle , Aethina tumida Murray ( Coleoptera : Nitidulidae ) , is a pest of colonies of social bees , including the honeybee Apis mellifera L. ( Hymenoptera : Apidae ) . - pubmed
Also discussed was the topic of cutaneous melanoma murine models outlining the role of these models in understanding the molecular pathways involved in melanoma initiation , progression , and metastasis . - pubmed
Chronic Kidney Disease and Hepatitis C Virus Treatment . - pubmed
On that ground , patients with these lymphomas should be strictly monitored . - pubmed
We aim to identify serum inflammatory mediators that are associated with outcome after intracerebral hemorrhage in order to translate data from experimental models to a patient cohort and identify potential targets worthy of reverse translation . - pubmed
Methods : A prospective cohort study at two comprehensive stroke centers enrolled patients with spontaneous intracerebral hemorrhage . - pubmed
Interpretation : Acute and subacute elevations in specific immune factors are associated with poor outcome , highlighting potential pathways that may contribute to ongoing brain injury in patients with intracerebral hemorrhage . - pubmed
Methods : Forty - five dental implants in 20 patients diagnosed with peri - implantitis were included . - pubmed
BACKGROUND : Schistosoma mansoni infection has been associated with increased risk of HIV transmission in African women . - pubmed
METHODS : HIV - uninfected non - pregnant adult women using public health services were tested for schistosomiasis using the urine circulating cathodic antigen test , followed by serology and Schistosoma spp.-specific PCR . - pubmed
All women infected by Chlamydia trachomatis ( n = 5 ) , were also positive for schistosomiasis ( Fisher 's exact p = 0.064 ) . - pubmed
These findings have implications for the design and interpretation of clinical studies on the effects of schistosomiasis on HIV acquisition . - pubmed
Thyme oil also showed antibacterial activity against MRSA and the antibiotic - sensitive strain of P. - pubmed
The aim of this study was to assess patient compliance , satisfaction and experience with the extended low molecular weight heparin prophylaxis after major surgery for gynaecological cancer . - pubmed
Consecutive patients undergoing surgery for gynaecological cancer who received low molecular weight heparin prophylaxis for four weeks following surgery were recruited . - pubmed
Daily adjustment of glucocorticoids by patients with adrenal insufficiency . - pubmed
AIM : To evaluate self - management of patients with AI . - pubmed
METHODS : We examined 781 patients who underwent hepatic resection for HCC . - pubmed
Successful management and recovery following severe prolonged starvation in a dog . - pubmed
CASE SUMMARY : A 7 - year - old , intact male Labrador Retriever presented with profound weakness and loss of nearly 50 % of his body weight due to severe prolonged starvation after being trapped in a well for 27 days . - pubmed
The dog 's electrolyte abnormalities resolved , wounds healed , and strength returned during the first 3 weeks of treatment . - pubmed
NEW OR UNIQUE INFORMATION PROVIDED : This report describes the management of a severely malnourished dog during refeeding , and highlights treatment considerations that may be important in the prevention of refeeding syndrome in such cases . - pubmed
Results : In patients with premenopausal breast cancer , the tumour diameter was larger ( p = 0.047 ) and the lymph node metastasis was higher ( p & lt ; 0.001 ) . - pubmed
The chapeau de gendarme sign has been associated with frontal lobe seizures in patients with focal epilepsy . - pubmed
We propose that the anterior insular cortex should be a site of investigation during pre - surgical phase 2 evaluation in patients exhibiting the chapeau de gendarme sign during focal seizures . - pubmed
Cistanche deserticola Y. C. Ma is known as a popular tonic herb traditionally used to treatment deficiency of kidney energy including muscle weakness in minority area of Asian counties . - pubmed
Based on the theory of " kidney dominate bone , " an ovariectomized ( OVX ) rat model of postmenopausal osteoporosis was used to evaluate the therapeutic effect of C. - pubmed
CONCLUSIONS : Overall psychological interventions for children and adults with type 1 diabetes do not improve glycaemic control . - pubmed
NCBP2modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models . - pubmed
Ultrasound Neuromodulation Inhibits Seizures in Acute Epileptic Monkeys . - pubmed
Recent studies have reported that ultrasound stimulation suppressed epileptic seizures in a rodent model of epilepsy . - pubmed
These findings raise the crucial question of whether ultrasound stimulation can inhibit seizures in non - human primates with epilepsy . - pubmed
We confirmed that ultrasound stimulation significantly reduced the frequency of seizures in acute epileptic monkeys . - pubmed
Our results are of great importance for future clinical applications of ultrasound neuromodulation in patients with epilepsy . - pubmed
RESULTS : We identified 35 articles including 2042 primary EOC patients ; one study was a randomized trial , and only six studies included a comparator group of surgery alone . - pubmed
[ Establishment and evaluation of multiplex PCR for detection of main pathogenic bacteria of endometritis in Tibetan sheep ] . - pubmed
A multiplex PCR method was developed to detect the main pathogens of Qinghai Tibetan sheep endometritis . - pubmed
The multiplex PCR method was successfully established and the main pathogens of endometritis in Qinghai Tibetan sheep were GBS , E. - pubmed
The invitro PDT is tested on murine breast 4T1 cancer cells incubated with 250 mug / mL of the nanoparticles and irradiated with NIR light under power density of 2 W / cm2for 10 minutes . - pubmed
Immunohistochemistry , Kaplan - Meier method and multivariate Cox regression assays were performed to examine the clinical correlation in tumor specimens from lung cancer patients . - pubmed
The inclusion of straw in high concentrate total mixed rations ( TMRs ) of male fattening goats can provide the necessary fiber to prevent ruminal acidosis and maintain growth . - pubmed
Thirty - two male Beetal goats ( 27.4 + - 0.28 kg body weight ( BW ) ) were divided randomly into the following four dietary treatments with a 2 x 2 factorial arrangement ( n = 8 / treatment ): ( 1 ) CTMR15 ( conventional TMR containing 15 % WS ) , ( 2 ) CTMR25 ( conventional TMR containing 25 % WS ) , ( 3 ) PTMR15 ( pelleted TMR containing 15 % WS ) , and ( 4 ) PTMR25 ( pelleted TMR containing 25 % WS ) . - pubmed
Ten healthy right - handed volunteers without any neurological disorders were enrolled . - pubmed
When the objects were placed on the unreachable spot , dogs looked at both objects for the same amount of time in the non - matching group , but longer at the toy in the matching group . - pubmed
Infection with Toxoplasma gondii is usually an asymptomatic or oligosymptomatic , self - limiting disease in immunocompetent individuals . - pubmed
Intracranial lipomata can be found in both symptomatic and asymptomatic patients . - pubmed
Tumor - associated humoral cytotoxicity in patients with acute myelogenous leukemia before and after chemotherapy . - pubmed
Sera of eight unselected adult patients with acute myelogenous leukemia obtained before and after chemotherapy were repeatedly tested for specific complement - dependent cytotoxicity against autochthonous peripheral white blood cells from the acute leukemia stage and from the remission stage , respectively . - pubmed
The cytotoxicity was increased after chemotherapy , also in those patients in whom remission was not achieved . - pubmed
Enumeration of Streptococcus mutans in human dental plaque after chewing gum sweetened with xylitol and sucrose . - pubmed
Liver changes were demonstrated in six elderly patients with giant - cell arteritis ( temporal arteritis , three with polymyalgia ) . - pubmed
28 patients with advanced mitral valve restenosis were studied by cardiac catherization on an average of 7.2 years after previous closed mitral valvotomy , performed using the Tubbs dilator technique . - pubmed
Report on a man of 29 years with acute bronchopneumonia , antibodies against Mycoplasma pneumoniae and acute pancreatitis lasting three weeks . - pubmed
Lymphocytes isolated from tonsils of patients undergoing tonsillectomy and from axillary lymph nodes of breast cancer patients exhibited approximately 30 % of cells with caps , which is identical with the cap formation ability of normal lymphocytes . - pubmed
In biopsy material from patients with Hodgkin ' s disease and other malignant lymphomas , a significant decrease in the ability of the lymphocytes to form caps was observed . - pubmed
In 123 patients with Hodgkin ' s disease and other malignant lymphomas , cap formation ranged between 3 and 12 % . - pubmed
Lymphocytes from patients with lymphoma were also agglutinated by Con A to a higher degree than normal lymphocytes . - pubmed
Immunological function in patients operated on with small intestinal shunts for morbid obesity . - pubmed
Obese individuals , operated on with intestinal shunts , have been investigated with regard to immunological functions . - pubmed
This study identified 2438 human immunodeficiency virus ( HIV)-seropositive active - duty enlisted Navy personnel , including 778 seroconverters . - pubmed
Focal glomerulosclerosis in children : an Argentinian experience . - pubmed
Twenty - six children presenting with idiopathic nephrotic syndrome and a histological diagnosis of focal glomerulosclerosis were studied retrospectively to evaluate their response to treatment , outcome and clinicopathological correlations . - pubmed
Twenty - two patients ( 84.6 % ) were steroid resistant ; of these , 8 of the 19 with focal segmental glomerulosclerosis and 2 of the 3 with focal global glomerulosclerosis responded to cyclophosphamide ( CY ) within 16 weeks of starting therapy . - pubmed
After an average follow - up of 83 months , 17 patients are in remission with normal renal function , 3 patients have persistent nephrotic range proteinuria and 6 patients are in chronic renal failure . - pubmed
Effects of pentisomide and E-4031 on canine atrial flutter due to reentry : a comparative study with disopyramide and propafenone . - pubmed
AF was induced with burst atrial pacing after we made an intercaval crush in anesthetized , open - chest dogs . - pubmed
Pentisomide and E-4031 were effective in terminating canine AF due to reentry , as were disopyramide and propafenone . - pubmed
Reinitiation of AF was greater in dogs treated with antiarrhythmic drugs that had more prominent effects on conduction time than on ERP . - pubmed
In the experiment on 60 dogs , it was established that the leading causes of unsatisfactory anastomotic healing in peritonitis were the disorders in hemocirculation and morphologic changes in the intestinal wall . - pubmed
The patient was pointed out to have papilledema and elevated intracranial pressure six years ago . - pubmed
Consequently , she was diagnosed as the benign intracranial hypertension and had been followed as an out patient . - pubmed
Data collected to investigate the effects of ticlopidine in a subset of 489 patients with angina at rest accompanied by transient ischaemic electrocardiographic changes have been analysed . - pubmed
Nineteen patients died ; 12 in the control group ( 4.7 % ) and seven in the ticlopidine group ( 83 % ) ( -36 % ) ( odds ratio : 0.62 ; confidence intervals : 0.21 , 1.74 ) ; five patients in the control group and only one in the ticlopidine group died of an AMI . - pubmed
Heparin prevents stasis - induced thrombosis through protection of the venous endothelial cells : an electron microscopic study in rabbits . - pubmed
Alterations in the pattern of epidermal differentiation and proliferation occur during mouse skin carcinogenesis . - pubmed
However , in carcinomas , the transcript levels for the Mr 67,000 and 59,000 subunits were only 1 - 3 % of those observed in untreated mouse epidermis . - pubmed
The effects of 2,2 '- O - cyclocytidine ( CC ) and acyclovir ( ACV ) on latent herpes simplex virus ( HSV ) in trigeminal ganglia were studied in an in vitro model using reactivation of HSV type 1 ( HSV-1 ) as a model . - pubmed
Therefore , the attempts to correct these neurohormonal imbalance in patients with heart failure has a sound rational basis , not only to improve the symptoms and the exercise capacity but also to increase the survival of these patients . - pubmed
Examination of oxidative metabolism in mitochondria isolated from quadriceps skeletal muscle biopsy specimens of 4 patients with Kearns - Sayre syndrome has shown that the mitochondria were tightly coupled , with maximal respiratory rates depending on the presence of adenosine diphosphate ( ADP ) , Ca2 + , or uncoupler . - pubmed
Deficient glucagon responses to decrements in plasma glucose , which are common in patients with IDDM and occur in some patients with NIDDM , result in altered counterregulation . - pubmed
Studies of verrucofortine toxicity in mice showed no apparent toxic effects at doses as high at 160 mg / kg ip . - pubmed
Bone marrow cells from most patients with acute promyelocytic leukemia contain a highly specific cytogenetic rearrangement , a reciprocal translocation between the long arms of chromosomes 15 and 17 . - pubmed
[ Immunocorrective therapy of patients with chronic active liver diseases of a viral nature ] . - pubmed
A study of the effect of immunocorrective drugs on the clinicobiochemical and immunological indices of patients with chronic active liver diseases of viral nature made it possible to work out criteria for administration of levamisole ( the absence of the cytolytic syndrome , the presence of immunodeficiency in the system of cellular immunity and disturbance of immunoregulation ) , prednisolone , the combination of prednisolone and azathioprine , and d - Penicillamine ( severe hepatocellular insufficiency , the presence of autoimmune reactions and disturbance of immunoregulation ) . - pubmed
The pharmacokinetics of ceftriaxone ( CRO ) after subcutaneous and intravenous administration was studied in 10 healthy volunteers ( 5 males , 5 females , age 22 - 43 years , body weight 64.3 + /- 9.5 kg ) . - pubmed
[ Immunochemical studies in various human myopathies ] . - pubmed
Oxygen consumption and tissue oxygen tension as a function of the hematocrit in polycythemic mice . - pubmed
jousseaumei ; the latter is probably the snail host of Schistosoma haematobium in one small village in the delta , where a low infection rate was reported by other workers . - pubmed
Preliminary data on the dexamethasone suppression test in children with major depressive disorder . - pubmed
The authors administered the dexamethasone suppression test to 14 children aged 5 - 12 years who met the Research Diagnostic Criteria and DSM - III criteria for major depressive disorder . - pubmed
2 patients developing acute alveolar hypoventilation following IPPB therapy are presented . - pubmed
There is a significant diminution in intracellular bactericidal activity of leukocytes with Staphylococcus aureus and Escherichia coli in subjects with poorly controlled diabetes in comparison with the control group . - pubmed
The indication for surgery was rest pain in 22 patients and actual tissue necrosis in 43 patients . - pubmed
Their antiproliferative effect has been found against a variety of animal and human tumor cell lines . - pubmed
We have characterized the cytostatic activity of four ether phospholipids , the methoxy - substituted edelfosine ( ET-18 - OCH 3 ) , the thio - derivative ilmofosine ( BM 41.440 ) , and two new aza - alkylphospholipids , BN 52205 and BN 52211 , on a human tumor cell line derived from a colon adenocarcinoma , the HT29 . - pubmed
We examined the effect of hypercholesterolemia on vasodilatory responses to clonidine in isolated and perfused rabbit common carotid arteries that had been preconstricted by phenylephrine . - pubmed
In 7 children impairment of hearing was observed after local therapy with neomycin and gentamicin because of scalding wounds . - pubmed
3 adults locally treated with aminoglycoside antibiotics ( neomycin , framycetin , gentamicin ) for ulcera cruris displayed a delayed development of hearing loss . - pubmed
[ The combined treatment of patients with locally disseminated prostatic cancer ] . - pubmed
A randomized study has been made to compare combined treatments of 111 patients with local prostatic cancer ( T2b-4N0 - 2M0 ) . - pubmed
Cytotoxicity of endogenous isoquinolines to human dopaminergic neuroblastoma SH - SY5Y cells . - pubmed
In this paper they were examined for the cytotoxicity of human dopaminergic neuroblastoma SH - SY5Y cells . - pubmed
Their baseline levels were found to be higher in patients with cancer of the lung , large bowel , and rectum than those in controls , which indicates higher lipid peroxidation , which led to the destabilization of cellular membranes and seems to cause baseline hypermyoglobinemia . - pubmed
Usefulness of subnormal midwall fractional shortening in predicting left ventricular exercise dysfunction in asymptomatic patients with systemic hypertension . - pubmed
However , it is unknown whether abnormal midwall fractional shortening predicts either subnormal LV functional reserve or extracardiac damage in asymptomatic hypertensive patients . - pubmed
Thus , subnormal midwall fractional shortening predicts depressed LV fractional reserve in asymptomatic hypertensive patients and may contribute to identification of patients with extracardiac target - organ damage . - pubmed
The performance of the whole system was tested on dog plasma samples including specimens taken after oral administration of the anti - Parkinsonism drug Duellin , which is a combination tablet of levodopa and carbidopa . - pubmed
METHODS : This single - center , randomised , double - blind study was conducted on 37 women with chronic lower - limb venous insufficiency , associating clinical or functional signs and abnormal plethysmographic values . - pubmed
Cost - effectiveness analysis of a dry powder inhaler ( Turbuhaler ) versus a pressurised metered dose inhaler in patients with asthma . - pubmed
In an open randomised parallel - group study , 1004 patients with asthma in 7 countries were randomised to receive asthma treatment via 2 different kinds of inhalers : an aerosol pressurised metered dose inhaler ( pMDI ) and a dry powder inhaler ( Turbuhaler ) . - pubmed
Lexical and conceptual components of stem completion priming in patients with Alzheimer ' s disease . - pubmed
This study evaluated the hypothesis of dissociation between normal lexical but deficient conceptual repetition priming in patients with Alzheimer ' s disease ( AD ) . - pubmed
For this purpose , we administered to patients with AD and age - matched normal controls the Stem Completion task . - pubmed
Probably due to a floor effect of performance in the graphemic condition , in Experiment 1 , AD patients exhibited lower priming than normal controls for the semantically processed words but comparable priming for the graphemically processed ones . - pubmed
In contrast , in Experiment 2 , AD patients were poorly primed both in the intra- and crossmodal conditions . - pubmed
Results question the hypothesis of a lexical / conceptual dissociation in the repetition priming exhibited by AD patients and call for other explicative hypotheses of the dissociation between normal and deficient forms of repetition priming in degenerative dementia . - pubmed
METHODS : Seven patients afflicted by neurogenic velopharyngeal incompetence were treated with wire - extension speech - aid prostheses constructed to circumvent the dysfunctional soft palate . - pubmed
CONCLUSION : Wire - extension speech - aid prostheses used by the patients were an effective treatment approach for velopharyngeal incompetence . - pubmed
Cholesterol standardized plasma vitamin E levels are reduced in patients with severe angina pectoris . - pubmed
Vitamin E , the major lipid soluble plasma antioxidant , has been reported to be reduced in patients with coronary atherosclerosis . - pubmed
We have measured the levels of plasma alpha - tocopherol ( the predominant form of plasma vitamin E ) in 128 patients with different reported degrees of angina . - pubmed
The groups of patients with angina did not differ significantly for mean age ( 58 + /- 1.0 years vs. 59 + /- 1.0 years , respectively ) ; sex distribution ( the M : F ratio was 48 : 16 and 46 : 18 for the respective groups ) ; or prevalence of smoking ( 12 % vs. 9 % ) , or hypertension ( 19 % vs. 33 % ) . - pubmed
The ratio between plasma vitamin E : total cholesterol was significantly lower in the patients with severe angina ( mean 2.20 + /- 0.09 mg / mmol ) vs. a mean value of 2.46 + /- 0 . - pubmed
The plasma vitamin E : total cholesterol ratio in patients with severe angina was also significantly lower ( P & lt ; 0.05 ) compared to either healthy controls with comparable total cholesterol levels ( n = 33 ) , or hypercholesterolaemic subjects ( n = 28 ) without symptomatic coronary disease ( mean ratios were 2.69 + /- 0.40 mg / mmol and 2.74 + /- 0.68 mg / mmol , respectively ) . - pubmed
Child and adolescent cancer patients who use tobacco present challenging management problems for the pediatric dentist . - pubmed
An approach to counseling patients about their oral health risks secondary to their cancer treatment , which can be adversely impacted by tobacco use , is discussed . - pubmed
Strategies for conducting dental examinations with pediatric cancer patients with attention to potential tobacco - related complications are also provided . - pubmed
METHODS : Two hundred subjects ( aged 51 - 88 years ) , 99 with and 101 without AAA as determined by previous ultrasound , each underwent physical examination of the abdomen by 2 internists who were blinded to each other 's findings and to the ultrasound diagnosis . - pubmed
We present the case of a patient with psoriasis in whom ulcerated atrophic striae developed during etretinate therapy . - pubmed
Subsequently , the patient had a favorable response to oral calcitriol ( 1,25 - dihydroxy vitamin D3 ) , a novel therapy for psoriasis . - pubmed
Abdominal lump in an infertile man . - pubmed
Alcohol and tobacco consumption may contribute to synchronous or metachronous head and neck cancer and esophageal cancer . - pubmed
Five patients ( 8.3 % ) had superficial esophageal cancer , which was diagnosed as intraepithelial carcinoma in three of them ( 5.0 % ) . - pubmed
Treatments that weaken Pavlovian conditioned fear and thwart its renewal in rats : implications for treating human phobias . - pubmed
In experiments using a total of 144 albino rat subjects , the authors assessed the ability of fear - weakening treatments to prevent fear renewal ( relapse ) . - pubmed
We assessed whether the quantification of cancer invasion into the perineural space influences the prognosis of patients treated with radical prostatectomy . - pubmed
We conducted a retrospective study of clinical and pathologic features in 640 consecutive patients with clinical stage Tla - T3bNXM0 prostate cancer who were treated with radical retropubic prostatectomy by the same surgeon between 1989 and 1995 . - pubmed
PATIENTS AND METHODS : Fourteen patients with severe atopic blepharitis were treated with topical FK 506 0.1 % . - pubmed
Every patient graded pruritus on a visual analogue scale . - pubmed
Effects of exercise training program on functional capacity and quality of life in patients with peripheral arterial occlusive disease . - pubmed
During course of intervention , patients demonstrated improvements in pain - free training walking distance ( p & lt ; 0.001 ) and repetitions of tiptoe standing ( p & lt ; 0.05 ) . - pubmed
Effect of ovariectomy , malnutrition and glucocorticoid application on bone properties in sheep : a pilot study . - pubmed
The demographic changes in the human population continue to lead to an increasing incidence of osteoporosis . - pubmed
There is a great need for a large - animal model of osteoporosis for controlled studies , which allows the investigation of fracture healing and fracture treatment in weak bone . - pubmed
The most effective method of inducing osteoporosis in sheep was found to be the combined treatment . - pubmed
Here we report the analysis of muscle biopsies from a DMD patient ( DMD - BMT1 ) who received bone marrow transplantation at age 1 year for X - linked severe combined immune deficiency and who was diagnosed with DMD at age 12 years . - pubmed
Seven patients were classified as suffering from Wegener ' s granulomatosis ( WG ) , 18 from microscopic polyangitis ( MPA ) , and the remaining 19 were unclassified ( unclassified small vessel vasculitis , USVV ) . - pubmed
RESULTS : The percentage of ENT manifestations in the early clinical picture of WG patients was 86 % , dropping to 44.5 and 22 % for MPA and USVV patients , respectively . - pubmed
The overall percentage of ENT manifestations for SVV patients in their initial clinical profile was 47 % . - pubmed
CONCLUSION : The results of our investigation highlight the importance of an ENT clinical examination as a guide for diagnosis of an important percentage of SVV patients . - pubmed
Epithelial splenic cysts in children : surgical treatment by cyst - wall " peeling " . - pubmed
Five consecutive splenic epithelial cysts in pediatric patients were treated by parenchyma - sparing complete removal of the cyst wall , which was gently peeled off the splenic tissue without major bleeding in all but one case . - pubmed
PURPOSE : The use of partial breast brachytherapy ( PBB ) after lumpectomy for selected patients with early - stage breast cancer reduces the adjuvant radiotherapy treatment time to & lt;1 week . - pubmed
METHODS AND MATERIALS : Early - stage breast cancer patients with clear resection margins and 0 - 3 positive lymph nodes were eligible for PBB . - pubmed
RESULTS : Between 1995 and 2000 , 44 patients with early - stage breast cancer received PBB without adjuvant external beam radiotherapy after lumpectomy ( 31 HDR PBB , 13 LDR PBB ) . - pubmed
Radiation recall reactions occurred in 43 % of patients ( 6 of 14 ) who received adriamycin . - pubmed
FACTORS ASSOCIATED WITH ANAPHYLACTIC REACTIONS TO CHICKEN EMBRYO FOOT - AND - MOUTH DISEASE VACCINE AND FLURY RABIES VACCINE IN CATTLE OF VENEZUELA . - pubmed
We report a 50 - year - old man with CBD stone formed around a surgical clip , who had undergone a laparoscopic cholecystectomy because of acute calculous cholecystitis 14 months before . - pubmed
OBJECTIVES : To evaluate the outcome of immunocompetent pediatric patients who had positive cytomegalovirus ( CMV ) antigenemia and received ganciclovir . - pubmed
RESULTS : Sixty - four patients with positive CMV antigenemia were identified ; 15 patients were excluded from the study because of their underlying diseases . - pubmed
We studied efficacy of predicting outcomes of the disease in 345 patients ( mean age 48.3 + /- 4.5 years ) with extra hospital pneumonia ( EHP ) . - pubmed
Recurrent Mycobacterium marinum tenosynovitis of the wrist mimicking extraarticular synovial chondromatosis on MR images . - pubmed
Tenosynovitis caused by atypical mycobacterial infections may produce rice bodies within affected tendon sheaths . - pubmed
marinum infection involving the flexor tendons within the carpal tunnel in which the rice bodies were mistaken for synovial chondromatosis on MR images . - pubmed
Recently , MRSI was successfully integrated into radiotherapy planning in prostate cancer patients . - pubmed
Whereas immune suppression is considered as a likely mechanism for exhaustive exercise - induced susceptibility to infection , we know little about viral - specific T - cell response following exhaustive exercise in young or old mice . - pubmed
In this study , one group of female young ( 10 - 12 wk ) and old ( 22 - 24 mo ) C57BL/6 mice was exposed to a single bout of intense exercise to exhaustion and immediately infected with lymphocytic choriomeningitis virus ( LCMV ) . - pubmed
Its overexposure in human beings can provoke significant effects including lung , cardiovascular and kidney diseases . - pubmed
Oral therapy with dipyridamole limits ischemia - reperfusion injury in humans . - pubmed
We hypothesize that treatment with the nucleoside uptake inhibitor dipyridamole increases endogenous adenosine and limits ischemia - reperfusion injury in humans . - pubmed
Population dynamics of nasal strains of methicillin - resistant Staphylococcus aureus -- and their relation to community - associated disease activity . - pubmed
METHODS : A randomized , controlled trial was used in Study 1 to compare a comprehensive family - based behavioral treatment program or an experimental treatment that incorporated reinforcing children for engaging in alternative behaviors to eating for 41 overweight 8- to 12 - year - old children . - pubmed
Study 2 used a within - subject design with baseline , enriched environment and a second baseline phase to determine the influence of providing activities that compete with eating for 13 overweight 8- to 12 - year - old children . - pubmed
We conducted a systematic review to assess the benefits and harms of ribavirin monotherapy for patients with chronic hepatitis C. - pubmed
It is suggested that Eptein - Barr virus ( EBV ) that contains the above deletion is not crucial for the development of the study lymphoproliferative malignancies . - pubmed
Etiology and effect on outcomes of hyperglycemia in hospitalized patients . - pubmed
PURPOSE : The prevalence of diabetes in U.S. hospitals , etiology and pathophysiology of hyperglycemia in hospitalized patients , impact of hyperglycemia on patient outcomes , and benefits of hyperglycemia correction are described . - pubmed
SUMMARY : Diabetes mellitus is a common and costly condition with an increasing prevalence in the U.S. Hyperglycemia is common among hospital patients with and without diabetes . - pubmed
The benefits of using intensive therapy to correct hyperglycemia in hospitalized patients in reducing mortality and the risk of infections and other adverse outcomes are well documented . - pubmed
CONCLUSION : Efforts are needed to manage hyperglycemia in hospitalized patients with and without diabetes to minimize the morbidity , mortality , and costs associated with hyperglycemia . - pubmed
More than 400 million people are susceptible to oxidative stress due to glucose-6 - phosphate dehydrogenase ( G6PD ) deficiency . - pubmed
[ The effectiveness of fenspiride in the treatment of patients with chronic obstructive pulmonary disease ] . - pubmed
The purpose of the study was to assess the effectiveness and safety of long - term application of fenspiride , an anti - inflammatory drug , in patients with chronic obstructive pulmonary disease ( COPD ) under outpatient conditions . - pubmed
The drug was studied on 24 COPD patients . - pubmed
Coronary artery disease ( CAD ) was diagnosed in 92 ( 53 % ) patients , and non - ischaemic cardiomyopathy in 82 ( 47 % ) patients . - pubmed
Indications for repeat procedures included battery depletion in 136 patients , ICD malfunction in 37 cases , infection related to the implanted system in 5 patients , problems with leads in 19 cases , an upgrade to the dual - chamber system in 5 or to the biventricular system in 3 patients , and the revision of an ICD pocket in 6 patients . - pubmed
Clinically useful " older " agents include topical azole formulations ( for superficial yeast and dermatophyte infections ) , first - generation triazoles ( fluconazole and itraconazole , for a range of superficial and invasive fungal infections ) , amphotericin B formulations ( for a broad range of invasive fungal infections ) and terbinafine ( for dermatophyte infections ) . - pubmed
Caspofungin and the other echinocandins are effective in treating Candida and Aspergillus infections . - pubmed
Further , it can also promote full - thickness cutaneous wound healing in BALB / c mice . - pubmed
Serious paravalvular leakage occurs in 1 - 5 % of patients who have undergone surgical cardiac valve replacement procedures . - pubmed
[ Effectiveness of prophylaxis against tuberculosis in patients infected with HIV ] . - pubmed
INTRODUCTION : Prophylaxis against tuberculosis has been recognized as important for preventing clinical forms of tuberculosis , mainly in HIV positive patients . - pubmed
The second group consisted of 200 patients selected from the records of a HIV / AIDS control program . - pubmed
CONCLUSION : The prophylaxis against tuberculosis was effective in HIV positive patients , independently of the immune status , viral load , and highly effective antiretroviral therapy . - pubmed
The author presents the case of a 62 - year - old obese Hispanic man , with newly diagnosed type 2 diabetes mellitus ( T2DM ) , diabetic peripheral neuropathy , background retinopathy , and diabetic nephropathy . - pubmed
In the present study , adult feeding and population density of the weevil , injury level of striped stem borer Chilo suppressalis ( Walker ) ( Lepidoptera : Pyralidae ) and pink stem borer Sesamia inferens ( Walker ) ( Lepidoptera : Noctuidae ) to rice , as well as growth status of their host plants were surveyed in a rice field located in Southeastern Zhejiang , China , in 2004 with the objective to discover interspecific interactions on the rice . - pubmed
MATERIALS AND METHODS : The treatment data of 7 patients with VMs from January 2005 to January 2006 were reviewed . - pubmed
Two patients had a fever during treatment , and one of them stopped treatment because of continuous high fever . - pubmed
Acute renal failure after exercise in a Japanese sumo wrestler with renal hypouricemia . - pubmed
Dietary high protein and vitamin C mitigates endosulfan toxicity in the spotted murrel , Channa punctatus ( Bloch , 1793 ) . - pubmed
Unique patterns of molecular profiling between human prostate cancer LNCaP and PC-3 cells . - pubmed
BACKGROUND : Human prostate cancer LNCaP and PC-3 cell lines have been extensively used to study prostate cancer progression and to develop therapeutic agents . - pubmed
One animal was excluded from the study due to complications in the TG during wound healing ; therefore , six dogs remained in the sample . - pubmed
Dog skin was sutured after punch biopsy and investigated histologically and immunohistochemically on days 0 ( normal ) , 1 , 3 , 5 , 7 , 10 , and 14 after injury . - pubmed
A human cadaver emergency procedure lab curriculum is uncommon . - pubmed
Response averages and 95 % confidence intervals for the preferred means of learning a new procedure are as follows : textbook ( 3.69 ; 3.51 - 3.87 ) , mannequin ( 2.83 ; 2.64 - 3.02 ) , human cadaver ( 1.93 ; 1.72 - 2.14 ) , and living patient ( 1.56 ; 1.33 - 1.79 ) . - pubmed
Response averages for the commonality of means used to teach a new procedure are as follows : human cadaver ( 3.63 ; 3.46 - 3.80 ) , mannequin ( 2.70 ; 2.50 - 2.90 ) , living patient ( 2.09 ; 1.85 - 2.33 ) , and textbook ( 1.57 ; 1.32 - 1.82 ) . - pubmed
MATERIALS AND METHODS : These women were diagnosed to have PCOS by the European Society of Human Reproduction and Embryology and the American Society of Reproductive Medicine , Rotterdam 2003 criteria . - pubmed
The common indications for CLKT in children are different from those of adults and include metabolic diseases affecting the kidney with or without liver dysfunction and congenital developmental abnormalities affecting both organs . - pubmed
To investigate the mechanisms of halothane - induced liver injury , we used a recently established mouse model of liver injury . - pubmed
Prophylactic immunization with AAV1 protected 100 % of the mice from tumor growth for more than 1 year , whereas all the control mice immunized with either a LacZ vector or saline grew large tumors and died within 6 weeks after inoculation of E7 - positive tumor cell line TC-1 . - pubmed
In addition , therapeutic immunization with AAV1 after palpable tumor formation inhibited tumor growth and caused tumor regression in some mice . - pubmed
Thus , our studies support the potential of AAV vectors as a genetic vaccine for the prevention and treatment of HPV - induced malignancies . - pubmed
Helicobacter pylori and gastric cancer : a marital risk ? - pubmed
Similarly , OLETF rats consumed significantly more of higher concentration corn oils than LETO while non - deprived sham feeding . - pubmed
Conversely , OLETF rats overconsumed low concentration corn oil compared to LETO during overnight deprived sham - feeding tests . - pubmed
Staphylococci ( both Staphylococcus aureus and coagulase - negative Staphylococcus ) have emerged as the most common cause of PVE and are associated with a severe prognosis . - pubmed
Systems for victim identification , arrangements for human remains , management of dead bodies , evaluation of the different patterns of injuries and , finally , detailed identification of the cause of death all played an important role . - pubmed
METHODS : We analyzed the transcriptome of human LNCaP prostate cancer cells as they progress to CRPC in vivo using replicate LongSAGE libraries . - pubmed
cerevisiae , Streptococcus pneumoniae ( a pathogen responsible for human pneumonia ) , Borrelia burgdorferi ( the pathogen that causes Lyme disease ) , and Plasmodium falciparum ( responsible for most human malaria ) are reported . - pubmed
OBJECTIVE : To investigate the effect of atorvastatin therapy on inflammation , disease activity , endothelial dysfunction , and arterial stiffness in patients with rheumatoid arthritis ( RA ) . - pubmed
METHODS : This study included 30 patients with early RA , randomly divided into 2 groups . - pubmed
CONCLUSION : Atorvastatin therapy in patients with RA reduced disease activity and conventional and novel vascular risk factors that promote the atheromatous lesion . - pubmed
A reduction of recipient regulatory T cells by cyclophosphamide contributes to an anti - tumor effect of nonmyeloablative allogeneic stem cell transplantation in mice . - pubmed
A donor lymphocyte infusion ( DLI ) in the cyclophosphamide - induced tolerant mice exerted strong anti - tumor effects on an MBT-2 murine bladder tumor , MBT-2 via their graft versus tumor ( GVT ) activity . - pubmed
The article presents the case of a 41 - year - old patient with a tumor of the distal third of left femur . - pubmed
In view of the possibility of NAHI , child protection investigations were initiated . - pubmed
N - acetylcysteine ( NAC ) has been recently proposed as an adjuvant therapeutic drug for influenza pneumonia in humans . - pubmed
This proposal is based on its ability to restrict influenza virus replication in vitro and to attenuate the severity of the disease in mouse models . - pubmed
Although available studies were made with different viruses ( human and avian ) , published information related to the anti - influenza spectrum of NAC is scarce . - pubmed
In this study , we show that NAC is unable to alter the course of a fatal influenza pneumonia caused by inoculation of a murinized swine H1N1 influenza virus . - pubmed
NAC was indeed able to inhibit the swine virus in vitro but far less than reported for other strains . - pubmed
Zoledronic acid to prevent bone loss in Chinese men receiving androgen deprivation therapy for prostate cancer . - pubmed
METHODS : Overall 26 prostate cancer patients with ADT were given zoledronic acid 4 mg by a 15 - min i.v . - pubmed
Seven patients had bone metastases . - pubmed
Risk factors and outcomes for patients with vascular disease and serious bleeding events . - pubmed
OBJECTIVE : To determine the risk and outcomes of serious bleeding events in patients with atherosclerotic vascular disease or risk factors . - pubmed
METHODS : 68 375 outpatients with prior ischaemic vascular events or multiple atherosclerotic risk factors were followed in this prospective observational study ; 64 977 had 1 - year follow - up data . - pubmed
Main outcome measures were rates of serious bleeding events and 1 - year outcomes for patients with and without serious bleeding events . - pubmed
Patients with symptomatic vascular disease had a haemorrhage rate of 1.0 % , compared with 0.59 % in those with risk factors only . - pubmed
METHODS : Retrospective claims data were analyzed for hypertensive adults with & gt;=1 year follow - up from first ARB claim . - pubmed
Response : Association between Diabetic Polyneuropathy and Chronic Complications in Type 2 Diabetic Patients ( Diabetes Metab J 2011;35:390 - 6 ) . - pubmed
Statins have been successfully used in patients with hypercholesterolemia and cardiovascular diseases , but there is increasing evidence that they exert effects by much exceeding the lowering of cholesterol levels . - pubmed
BACKGROUND : Locally advanced breast cancer ( LABC ) is common in developing countries and it frequently affects younger women . - pubmed
CONCLUSIONS : despite the use of standard multi - modality approach in the management of patients with LABC , prognosis remains guarded . - pubmed
RESULTS : New - confirmed T2DM patients with the significantly abnormal statistic results about AIR3.5 and ISI , while NGT patients had the abnormal results compared with normal control group but better than T2DM patients . - pubmed
CONCLUSION : Compared with normal group patients , NGT group appeared decrease of pancreases first phase secretes and insulin resistance but not aggravate enough to induce type 2 diabetes . - pubmed
Prevalence and length of recovery of pusher syndrome based on cerebral hemispheric lesion side in patients with acute stroke . - pubmed
METHODS : A total of 1660 patients with acute stroke were investigated . - pubmed
Risk ratios were used to evaluate the differences in the prevalence of PB between right cerebral hemisphere - damaged ( RCD ) and left cerebral hemisphere - damaged ( LCD ) patients . - pubmed
CONCLUSIONS : The number of RCD patients who exhibited PB was higher than that of LCD patients . - pubmed
Notably , impaired immunity in DR3(KO ) hosts on a C57BL/6 background was associated with 4- to 7 - fold increases in viral loads during the acute phase of infection , and in mice with suboptimal NK responses was essential for survival ( 37.5 % ) . - pubmed
Does metabolic compensation explain the majority of less - than - expected weight loss in obese adults during a short - term severe diet and exercise intervention ? - pubmed
DESIGN : In all , 16 obese men and women ( 41 + - 9 years ; body mass index ( BMI ) 39 + - 6 kg m(-2 ) ) were investigated in energy balance before , after and twice during a 12 - week very - low - energy diet(565 - 650 kcal per day ) plus exercise ( aerobic plus resistance training ) intervention . - pubmed
On the day of admission , the 24 - item Western Ontario and McMaster Universities Arthritis Index ( WOMAC ) was used to evaluate each patient 's pain and functional capacity before surgery . - pubmed
Of the 31 patients receiving lidocaine patch 5 % , 94 % of the patients reported satisfaction and attributed pain relief to its use . - pubmed
CONCLUSIONS : Overall , the concurrent use of lidocaine patch 5 % in treating the postoperative pain of patients after TKA does not provide significant additional pain relief compared with control subjects . - pubmed
In addition , tumor pathology was able to divide not only the patients as a whole ( p<0.001 ) , but also both patients with stage IVa ( p=0.007 ) and IVb ( p=0.007 ) , into two groups for overall survival , respectively . - pubmed
Tumor pathology is not only associated with the overall survival but is also able to divide both patients as a whole and those sub - classified by stage , into two independent groups before surgery . - pubmed
Transgenic resistance confers effective field level control of bacterial spot disease in tomato . - pubmed
We investigated whether lines of transgenic tomato ( Solanum lycopersicum ) expressing the Bs2 resistance gene from pepper , a close relative of tomato , demonstrate improved resistance to bacterial spot disease caused by Xanthomonas species in replicated multi - year field trials under commercial type growing conditions . - pubmed
Porphyromonas gingivalis is a major etiological agent in chronic and aggressive forms of periodontal disease . - pubmed
The transcriptome analysis confirmed the expression of all predicted ORFs for strain ATCC 33277 , including 854 hypothetical proteins , and allowed the identification of hitherto unknown transcriptional units . - pubmed
Acute demyelination in a person with amphetamine abuse . - pubmed
We report the case of a 31 - year - old woman , admitted to the hospital for chest pain , dying a few days later from septic multiorgan failure , and showing at autopsy foci of acute demyelination in the occipital lobe . - pubmed
This study investigates the role of oxidative damage causing haemolysis as a possible factor contributing to reduced red blood cell survival and thereby to renal anaemia in patients on chronic haemodialysis . - pubmed
MATERIAL AND METHODS : Patients who tested positive for H. - pubmed
We report a case of early bioprosthetic valve calcification in a 76 year - old woman who had received supplementation with alfacalcidol , an analogue of vitamin D , for 3 years after her initial valve replacement . - pubmed
The antiherpetic efficacy of MI - S was assessed in murine ocular , cutaneous , and genital infection models of HSV . - pubmed
Topical application of MI - S on skin lesions was also not effective , but cutaneously infected mice treated orally with MI - S had significantly reduced disease scores ( P & lt ; 0.05 ) after day 9 , suggesting that healing was accelerated . - pubmed
Patients presenting with synchronous or metachronous colorectal cancer liver metastases ( CLM ) should be evaluated for multimodal management with curative intent . - pubmed
Preoperative systemic chemotherapy shows beneficial impact on adjuvant progression - free survival and also borderline on overall survival , without significantly increasing initially R0 resectable patients postoperative complication rates . - pubmed
Antibiotics for human toxoplasmosis : a systematic review of randomized trials . - pubmed
The present study determined the impact of 5 Hz repetitive transcranial magnetic stimulation ( rTMS ) over the SMA on a fine motor movement , handwriting ( writing cursive " l"s ) , and on cortical excitability , in individuals with PD . - pubmed
In a cross - over design , ten individuals with PD were randomized to receive either 5 Hz or control stimulation over the SMA . - pubmed
Further , these data may provide the foundation for a larger investigation of the effects of noninvasive brain stimulation over the SMA in individuals with PD . - pubmed
OBJECTIVE : To investigate the relationship between the clinical features , pathogenesis , immunophenotype , different classification models and prognosis in Chinese patients with diffuse large B - cell lymphoma ( DLBCL ) . - pubmed
RESULTS : ( 1 ) Kaplan - Meier univariate analysis of the clinical data of 147 DLBCL patients found that the 3 - year overall survival ( OS ) rates were better in early stage ( P=0.032 ) , low IPI score ( P=0.001 ) , less than one extranodal involvement ( P=0.014 ) , and complete remission ( P<0.01 ) . - pubmed
METHODS : A total of 28 eyes from 28 patients presenting with primary open angle glaucoma who underwent NPDS were studied . - pubmed
This is the first report of congenital adrenal hyperplasia ( CAH ) due to combined 17alpha - hydroxylase / 17,20 lyase deficiency in an Omani patient who was initially treated for many years as a case of hypertension . - pubmed
A 22 - year - old woman who was diagnosed to have hypertension since the age of 10 years who was treated with anti - hypertensive therapy was referred to the National Diabetes and Endocrine Centre , Royal Hospital , Oman . - pubmed
The patient was treated with dexamethasone and ethinyl estradiol with cessation of anti - hypertensive therapy . - pubmed
BACKGROUND : Patients with mild cognitive impairment ( MCI ) have varying risks of progression to Alzheimer ' s disease ( AD ) . - pubmed
METHODS : 119 blood plasma samples of patients with MCI with different outcomes ( stable MCI and progressive MCI ) were analyzed by untargeted , label - free shotgun proteomics . - pubmed
Early results of anterior elbow release with and without biceps lengthening in patients with cerebral palsy . - pubmed
PURPOSE : To investigate the effect of partial biceps lengthening on elbow flexion posture and active elbow flexion and extension in patients with cerebral palsy . - pubmed
METHODS : We retrospectively reviewed 29 patients with cerebral palsy who underwent anterior elbow release as part of multilevel upper extremity surgery . - pubmed
CONCLUSIONS : Early results of partial lengthening of the biceps tendon showed that it may improve elbow flexion posture and active elbow extension in patients with flexion deformity in cerebral palsy . - pubmed
The PHMD method detected 96.6 % IC events in THA patients and 99.1 % in CPP patients with an average error of 5.3 ms and 18.4 ms . - pubmed
The HPA method detected 99.1 % IC events in THA patients and 97.3 % IC events in CPP patients , with an average error of 57.5 ms and 10.2 ms . - pubmed
Children with intractable epilepsy benefit from early surgical treatment when possible to reduce long - term morbidity . - pubmed
OBSERVATION : We report a case series of 3 patients with ACG that developed on long - haul flights . - pubmed
CONCLUSION AND RELEVANCE : Individuals with risk factors should be advised on the symptoms of ACG and the appropriate course of action should those symptoms occur . - pubmed
CASE DESCRIPTION : The authors present a case of a 47 - year - old female who presented with clinical features mimicking an acute spinal disorder but later found to have an adhesive arachnoiditis . - pubmed
To examine the association between markers of macromolecular oxidative damage and risk of NTDs , we measured levels of 8 - hydroxy-2 '- deoxyguanosine ( 8 - OHdG ) , protein carbonyl ( PC ) , and 8 - iso - prostaglandin F2alpha ( 8 - iso - PGF2alpha ) in maternal serum samples of 117 women with NTD - affected pregnancies and 121 women with healthy term newborns . - pubmed
METHODS : For 96 A / H3N2 virus isolates the 50 % inhibitory concentration ( IC50 ) ( 48 each from the 2011 - 12 and 12 - 13 influenza seasons ) was measured . - pubmed
Isovaline attenuates generalized epileptiform activity in hippocampal and primary sensory cortices and seizure behavior in pilocarpine treated rats . - pubmed
However , 30 % of patients with epilepsy are not adequately treated with anti - seizure medications and are considered intractable . - pubmed
Isovaline also attenuated hippocampal epileptiform activity and behavioral seizures in vivo in rats administered 4 aminopyridine ( 4AP ) . - pubmed
Here , we investigate whether isovaline is efficacious in attenuating secondarily generalized epileptiform activity and behavioral seizures in rats administered pilocarpine . - pubmed
The mosquito , Culex pipiens pallens ( L. ) , is an important vector of encephalitis and filariasis in northern China . - pubmed
A 61 - year - old woman presented with thigh pain and gait disturbance due to weakness in her lower right extremity . - pubmed
Immediately after surgery , the patient 's thigh pain resolved and she remained stable with normal vital signs . - pubmed
The patient was discharged 14 days after surgery without leg pain or any respiratory problems . - pubmed
Ectopic Schistosoma mansoni Eggs Inside a Lipoma . - pubmed
This report presents the first described case of ectopic Schistosoma mansoni eggs inside a subcutaneous lipoma far from the tissues of this worm 's life cycle and with no connection to either portal veins or any other vascular system . - pubmed
We describe the case of a 25 year old man following bariatric surgery who increased his ingestion of ondansetron , taking up to 40 tablets / day due to excessive nausea and vomiting . - pubmed
The patient was hospitalized for progressively more severe headache of 1 week 's duration . - pubmed
Three days into his admission , following improvement in his BP with oral anti - hypertensive but continued use of the ondansetron , the patient developed near complete blindness . - pubmed
Bioaccumulation , oxidative stress and genotoxicity in fish ( Channa punctatus ) exposed to a thermal power plant effluent . - pubmed
STUDY DESIGN : Eligible infants aged & lt;=4 months presenting to the main pediatric emergency service with apnea associated bronchiolitis were stratified by gestational age ( & lt;34 weeks or longer ) and randomized to receive a single dose of intravenous 25 mg / kg caffeine citrate or saline placebo . - pubmed
RESULTS : A total of 90 infants diagnosed with viral bronchiolitis associated with apnea ( median age , 38 days ) were enrolled . - pubmed
The recent advances in the study of the human papillomavirus ( HPV ) infection ( the necessary cause for CxCa development ) have guided clinical practice to add HPV related tests alongside the Pap test . - pubmed
METHODS : From May to November in 2014 , anonymous questionnaires were distributed to adult CML patients who were receiving TKI treatment all over China . - pubmed
Association between desloratadine and prednisolone in the treatment of children with acute symptoms of allergic rhinitis : a double - blind , randomized and controlled clinical trial . - pubmed
OBJECTIVE : To evaluate safety and efficacy of desloratadine plus prednisolone in the treatment of acute symptoms of children ( 2 - 12 years ) with allergic rhinitis , and to compare it to dexchlorpheniramine plus betamethasone . - pubmed
METHODS : Children with moderate / severe persistent allergic rhinitis and symptomatic ( nasal symptoms score [ 0 - 12]>=6 ) were allocated in a double - blind , randomized fashion to receive dexchlorpheniramine plus betamethasone ( n=105 ; three daily doses ) or desloratadine plus prednisolone ( n=105 ; single dose followed by two of placebo ) for 7 days . - pubmed
CONCLUSION : The desloratadine plus prednisolone combination was able to effectively control acute symptoms of rhinitis in children , improving symptoms and nasal function . - pubmed
The 18F - labeled compounds were evaluated in nude mice bearing LNCaP tumors and compared to [ 68Ga ] Ga - PSMA - HBED - CC and [ 18F ] DCFPyL. - pubmed
Microcystic macular edema in a case of tobacco - alcohol optic neuropathy . - pubmed
Ten pediatric patients who underwent ventricular tachycardia ablation were transferred immediately postablation to a 1.5 T MRI scanner and late gadolinium enhancement ( LGE ) imaging was performed to characterize ablation lesions . - pubmed
All patients underwent radiofrequency catheter ablation of ventricular arrhythmia with acute procedural success . - pubmed
LGE was identified at the reported ablation site in 9/10 patients , all arrhythmia - free at median 7 months follow - up . - pubmed
We examine host - associated variation in larval performance ( survivorship , development time , and adult body weight ) and oviposition preference , within and between two populations ofStator limbatus ( Coleoptera : Bruchidae ) that differ in the hosts available to them in nature . - pubmed
Sleep disorders require a comprehensive evaluation and confirmation with polysomnography in patients with multiple sclerosis . - pubmed
The prognosis of patients with WD is excellent , especially for those without cirrhosis at the time of diagnosis , but requires timely initiation of appropriate therapy specific for WD and for the patient 's liver disease independent of WD . - pubmed
However , they also focused on the preictal stage of NO - triggered and native human migraine attacks and suggested a predominant role of the hypothalamus shortly before the beginning of migraine headaches as well as alterations in hypothalamic functional connectivity . - pubmed
Results showed that ethanol feeding exacerbates the progression of hepatic tumors ( characterized by the ratio of liver weight to body weight , and the tumor volume and diameter ) in DEN - treated mice . - pubmed
METHODS : In AD patients and controls the expression of enzymes involved in the biosynthesis of FFAs and CERs was analyzed in relation to the SC lipid composition . - pubmed
In TH2 treated human skin equivalents ( AD HSEs ) mimicking lesional AD skin , the mRNA expression of these enzymes was investigated . - pubmed
For patients who underwent internal suspension technique , the surgeons preserved the external fat of the renal tumor as a suspension traction measure when separating the kidney . - pubmed
Patients with obesity are more prone to experience opioid - related adverse events ( ORAE ) . - pubmed
OBJECTIVES : The objective of this study is to determine if a multimodal analgesia protocol ( MAP ) reduces ORAE and provides effective pain relief for patients after LSG . - pubmed
CONCLUSION : Our study suggests that a MAP reduces ORAE and provides effective pain relief for patients undergoing LSG . - pubmed
DIAGNOSIS AND SUCCESSFUL TREATMENT OF A POTENTIALLY ZOONOTIC DERMATOPHYTOSIS CAUSED BY MICROSPORUM GYPSEUM IN A ZOO - HOUSED NORTH AMERICAN PORCUPINE ( ERETHIZON DORSATUM ) . - pubmed
A female North American porcupine ( Erethizon dorsatum ) was evaluated for a unilateral pedal crusting and alopecic dermatopathy . - pubmed
Fungal culture and histopathology testing revealed Microsporum gypseum dermatophytosis . - pubmed
We report a case of GPPD in an elderly white man who had an eruption involving the majority of the lower legs . - pubmed
In this study we used a mouse model of neuropathic pain to dissociate these factors . - pubmed
We performed RNA - seq on purified peripheral afferent neurons , but found no striking differences in gene expression between male and female mice , neither before nor after nerve injury . - pubmed
The majority of the screened compounds displayed potent anticancer activity against both HCT116 and HepG2 human cancer cell lines . - pubmed
Complex three - dimensional ( 3D ) in vitro models that recapitulate human tumor biology are essential to understand the pathophysiology of the disease and to aid in the discovery of novel anti - cancer therapies . - pubmed
In the future , 3D cultures will be instrumental for understanding the mode of action of drugs , identifying genotype - drug response relationships and developing patient - specific and personalized cancer treatments . - pubmed
Patients with biochemically and histologically proven papillary thyroid cancer ( PTC ) and ATC were included . - pubmed
Tumor - bearing mice ( 10 / group ) were administered 10 mg / kg lenvatinib ( p.o . ) - pubmed
Gene expression in patient - derived PTC and ATC cells was compared using a microarray approach . - pubmed
Tumor volume and cell properties were examined in the mouse xenograft model . - pubmed
PARTICIPANTS : Individuals aged 65 and older treated with DAA therapy for hepatitis C virus ( HCV ) during the study period ( N=113 ) divided into 2 cohorts : aged 65 to 74 ( n=88 ) and aged 75 and older ( n=25 ) . - pubmed
CONCLUSION : DAA therapy is highly efficacious for the treatment of HCV in older adults , but those aged 75 and older are more likely to have clinically significant pretreatment DDIs and experience AEs , including ribavirin - induced anemia , during therapy . - pubmed
To study this issue , we created a decision - model comparing proton vs. X - ray radiotherapy for locally advanced non - small cell lung cancer patients . - pubmed
For patients treated with IMRT experiencing grade 4 pneumonitis or grade 4 esophagitis , costs exceeded patients treated with protons without this toxicity . - pubmed
3DCRT patients with grade 4 esophagitis had higher costs than proton patients without this toxicity . - pubmed
In our continuing search for anticancer agents from higher plants , a chloroform extract of the leaves and twigs of Syzygium corticosum collected in Vietnam was found to be active toward the HT-29 human colon cancer cell line . - pubmed
Two - hundred and ninety patients with MVD and/or UPLMD who were treated consecutively with percutaneous coronary intervention ( PCI ) were included in the present study . - pubmed
Results : Of 227 patients with open emergency appendectomy for complicated appendicitis , 114 had received abdominal drain after the surgery . - pubmed
Local Anesthetic Wound Infiltration after Osteosynthesis of Extracapsular Hip Fracture Does Not Reduce Pain or Opioid Requirements : A Randomized , Placebo - Controlled , Double - Blind Clinical Trial in 49 Patients . - pubmed
The patients received intraoperative infiltration followed by 6 postoperative injections through a wound catheter in eight - hour intervals . - pubmed
A wide variability of motor phenotype has been observed in the different murine models of AD , without a consistent correlation with the extent of cerebellar histopathological changes or with cognitive deficits . - pubmed
The loss of noradrenergic drive may contribute to the impairment of cerebellar synaptic function and motor learning observed in these mice . - pubmed
Methods : The study enrolled 100 patients with peripheral arterial disease ( PAD ) and 100 patients with RA . - pubmed
Here we report the molecular characterisation of a novel dsRNA virus isolated from the filamentous , plant pathogenic fungus Leptosphaeria biglobosa and known to cause significant alterations to fungal pigmentation and growth and to result in hypervirulence , as illustrated by comparisons between virus - infected and -cured isogenic fungal strains . - pubmed
In clinical patients , enlarged LA was associated with older age , atrial fibrillation , hypertension , heart failure , inpatient status and biventricular dilatation . - pubmed
The use of TDM offers the possibility of a more personalized treatment approach for patients with IBD . - pubmed
Compared with ViVc , ViVr patients presented twice as early after surgical heart valve ( SHV ) implantation ( 55.2 + -36.1 vs. 118.4 + -57.7 months , p<0.001 ) , were more commonly female ( 82.8 % vs. 41.3 % , p<0.001 ) , and had shorter body stature and reduced body weight ( p<0.05 for both ) prior to PS . - pubmed
T - bet+ B cells have emerged as a key component of the humoral immune response in both infections and autoimmune disorders , with many of their phenotypic and functional attributes conserved between mice and humans . - pubmed
METHODS : Long - term 5 - year MacNab outcomes , visual analogue scale ( VAS ) scores , complications , and unintended aftercare were analyzed in a series of 86 patients who underwent endoscopic transforaminal foraminoplasty for foraminal stenosis . - pubmed
Postoperative dysesthesia occurred in 9 patients . - pubmed
Another 9 patients had recurrent disc herniations ( 10.5 % ) . - pubmed
Failure to cure with persistent pain occurred in 3 patients . - pubmed
Two patients developed pain postoperatively stemming from a different level . - pubmed
One patient experienced a postoperative hematoma which ultimately was inconsequential and did not require any additional surgery . - pubmed
CONCLUSION : Patients with symptomatic foraminal stenosis may be treated successfully with early transforaminal endoscopic decompression while maintaining favorable long - term outcomes without the need for fusion in the vast majority of patients . - pubmed
Salmonella , Staphylococcus aureus , Clostridium perfringens and Bacillus cereus were the main bacteriological agents to cause illness , but there were far fewer incidents of salmonellosis in 1981 ( 36 ) compared with 1980 ( 64 ) . - pubmed
Eight incidents of waterborne disease , caused by Giardia lamblia , Campylobacter , Salmonella , Pseudomonas aeruginosa and an undetermined agent , are double the number recorded for both 1980 and 1979 . - pubmed
Given that herpesviruses are arguably the most prevalent opportunistic pathogens and often reactivate in the elderly , it is reasonable to argue reactivation of herpesviruses might be major culprits for initiating AD in individuals carrying AD susceptibility genes . - pubmed
The Eunice Kennedy Shriver National Institute of Child Health and Human Development , in collaboration with the National Heart , Lung , and Blood Institute and the US Food and Drug Administration , sponsored a workshop of experts to discuss the current state of childhood primary hypertension . - pubmed
We investigated the spatiotemporal deterioration patterns of brain structures in patients with subcortical infarction and identified the regions that contributed to verbal memory impairment . - pubmed
Cognitive assessment and structural magnetic resonance imaging were performed 1 , 4 , and 12 weeks after stroke onset in 28 left - hemisphere and 22 right - hemisphere stroke patients with subcortical infarction . - pubmed
Practitioner Summary : Confusion arising from look - alike drug names may compromise patient safety . - pubmed
Abstract : The ketogenic diet ( KD ) is a high - fat and very low - carb diet , which has been used primarily for treatment of therapy - resistant epilepsy in children . - pubmed
Nevertheless , study results are too heterogenic for a general recommendation of the KD in this patient population . - pubmed
Drug - coated balloon for treatment of de - novo coronary artery lesions in patients with high bleeding risk ( DEBUT ): a single - blind , randomised , non - inferiority trial . - pubmed
BACKGROUND : The optimal technique of percutaneous coronary intervention in patients at high bleeding risk is not known . - pubmed
Patients were eligible if they had an ischaemic de - novo lesion in a coronary artery or bypass graft that could be treated with drug - coated balloons , at least one risk factor for bleeding , and a reference vessel diameter of 2 5 - 4 0 mm . - pubmed
INTERPRETATIONS : Percutaneous coronary intervention with drug - coated balloon was superior to bare - metal stents in patients at bleeding risk . - pubmed
GETV infection in horses has been reported in Japan and India , and causes great economic losses . - pubmed
Blood samples were collected from the sick horse , and PCR / RT - PCR analysis was performed to screen for equine viral pathogens associated with fever . - pubmed
Phylogenetic analysis indicated that GZ201808 clustered in Group III , and was located in an independent branch distant from other horse - derived GETV strains , indicating a unique evolutionary pattern of GZ201808 . - pubmed
This study first determined and described the disease course of horse infected with GETV in China , sequenced and characterized the genome of the field horse - derived GETV strain , and therefore presented an unequivocal report of GETV infection in horses in China . - pubmed
RESULTS : R6/1 mice were deficient in instinctive and anxiety related behaviors as well as long - term memory capabilities . - pubmed
Subgroup analysis found that ORs of studies in hemodialysis patients ( OR = 4.89 , 95 % CI 2.54 - 9.90 , p < .001 ) and acute ischemic stroke patients ( OR = 1.60 , 95 % CI 1.14 - 2.25 , p = .007 ) were higher than general population ( OR = 1.15 , 95 % CI 1.03 - 1.29 , p = .01 ) . - pubmed
Should We Investigate Osteoarticular Infections for Kingella kingae in Older - than - expected Immunocompetent Children ? - pubmed
Results : A 49 - year old Caucasian man with a family history of retinitis pigmentosa , presented with low vision and night blindness from early childhood . - pubmed
Evaluation of morphokinetic characteristics of zona pellucida free mouse pre - implantation embryos using time - lapse monitoring system . - pubmed
METHODS : Eleven patients with systemic amyloidosis were reviewed retrospectively . - pubmed
RESULTS : On ICGA , all patients exhibited hyperfluorescent spots in the late stage and were classified according to pre - existing criteria . - pubmed
BACKGROUND : Patients with malnutrition have a high risk of postoperative complications in total knee arthroplasty ( TKA ) . - pubmed
The rtM204I / sW196 * transformants , compared with the control or wild type , showed enhanced transactivation activities for c - fos , increased cell proliferation , decreased apoptosis , more anchorage - independent growth , and enhanced tumor growth in mouse xenografts . - pubmed
GSDIa patients are characterized by hypoglycemia , hepatomegaly , hyperlipidemia , and hyperlactacidemia . - pubmed
PATIENTS AND METHODS : Clinical data on GSDIa patients ' characteristics were collected . - pubmed
RESULTS : A total of 163 GSDIa patients were enrolled in this study . - pubmed
Effect of intentional restriction of venous return on tissue oxygenation in a porcine model of acute limb ischemia . - pubmed
We investigated whether partial venous occlusion in the common iliac vein ( CIV ) causes a further increase of venous oxygenation in a porcine model of acute hindlimb ischemia . - pubmed
Progesterone treatment does not decrease serum levels of biomarkers of glial and neuronal cell injury in moderate and severe TBI subjects : A secondary analysis of the Progesterone for Traumatic Brain Injury , Experimental Clinical Treatment ( ProTECT ) III trial . - pubmed
EV demonstrates a favorable profile in heavily pretreated patients with locally advanced or metastatic urothelial carcinoma . - pubmed
[ Correlations between alpha 1 - antitrypsin deficiency and some exogenous risk factors in patients with chronic obstructive bronchopneumopathy ] . - pubmed
Three beta1 - selective beta - blocker ( metoprolol , practolol and H 87 / 07 ) were compared in 29 patients with stable angina pectoris . - pubmed
Except for one patient who experienced a severe exanthema on practolol , the three beta - blockers were equally well tolerated . - pubmed
Also the clinical condition of thyrotoxicosis appeared to be correlated with FT3 concentrations ( toxic patients , group as a whole : 9.6 + /- 4.0 pg / ml ; euthyroid patients : 6.8 + /- 3.1 ; toxic patients with normal values of T3 and T4 ; 8.3 + /- 2.8 ) . - pubmed
Experimental right ventricular hypertrophy and failure in swine . - pubmed
Following pulmonary arterial constriction , 22 pigs developed right ventricular failure and 10 right ventricular hypertrophy . - pubmed
Comparing results with those obtained in 21 normal pigs ( no pulmonary artery constriction ) , it was found the right ventricular peak systolic and end - diastolic pressures , cardiac output , and right ventricular weight distinguished hypertrophied and failing hearts from normal ones . - pubmed
coli strains and with mice LS fibroblasts in vitro . - pubmed
[ Idiopathic thrombocytopenic purpura in children and in adults . - pubmed
To further examine whether the acquisition of the two ts-1[E ] lesions will predictably attenuate new influenza A variants , the HK / 68 - ts-1[E ] virus was mated with the A / Vic / 3 / 75 wild - type virus . - pubmed
Steatocystoma multiplex in a dog . - pubmed
DNA was extracted from isolates of bacteriophages grown on virulent and avirulent strains of Agrobacterium tumefaciens . - pubmed
12 patients with pain in the piso - triquetral region are described . - pubmed
[ Silent ischemic heart diseases in patients with peripheral arterial diseases . - pubmed
Silent ischaemic heart disease was looked for by exercise stress testing in 418 patients with chronic obliterative arterial disease of the lower limbs with no clinical or electrocardiographic signs of myocardial ischaemia . - pubmed
Patients who had a positive exercise stress test initially had a particularly high death rate ( 23 % ) and developed clinical signs of coronary insufficiency in 57.5 % of cases . - pubmed
Silent ischaemic heart disease is very prevalent in patients with obliterative arterial disease of the lower limbs and is a main vital prognostic factor in these patients . - pubmed
These results confirm the need for a complete cardiovascular check - up in all patients with peripheral arterial disease . - pubmed
Aluminium production plant workers are exposed to a great number of airborne polycyclic aromatic hydrocarbons and epidemiological studies suggest that these workers are at increased risk of lung and bladder cancer . - pubmed
A total of 254 patients with a history of two or more duodenal ulcers , the most recent event diagnosed within three months of study entry , were entered into the trial after healing was documented . - pubmed
Patients received sucralfate 1 g twice daily or placebo for four months , or until recurrence . - pubmed
At four months , there were 49 recurrences among 122 patients in the sucralfate group and 71 among 117 patients for the placebo group . - pubmed
At four months , there were 38 recurrences among 114 patients in the sucralfate group and 54 among 104 patients for the placebo group . - pubmed
Rupture of the spleen occurred in two patients ( a man of 32 and a girl of 16 years ) with serologically proven infectious mononucleosis . - pubmed
Ceftazidime was tested against 2,224 strains of Pseudomonas aeruginosa obtained from 17 hospitals in April , May and June , 1986 and against 607 strains of Klebsiella pneumoniae and 234 strains of K. - pubmed
Comparison of these results with those of studies performed in 1984 and 1985 showed a moderate increase in the number of intermediate sensitivity strains of P. - pubmed
[ African horse sickness in Senegal : the state of natural and/or acquired immunity in horses in a recent foci ] . - pubmed
Adenocarcinoma from endometriosis causing urinary tract obstruction in a patient on oestrogen replacement therapy after hysterectomy . - pubmed
A patient on oestrogen replacement therapy after hysterectomy developed endometriosis and adenocarcinoma . - pubmed
ST - T isointegral analysis of exercise stress body surface mapping for identifying ischemic areas in patients with angina pectoris . - pubmed
In 28 patients with angina pectoris and 10 healthy subjects , body surface potential was recorded with 87 leads , and ST isopotential and ST - T isointegral maps were constructed . - pubmed
In 23 of 28 patients with angina pectoris ( 82 % ) , alterations in the ST - T isointegral map after exercise were observed . - pubmed
In five patients ( 18 % ) who did not show abnormalities on the postexercise ST - T isointegral map , the magnitude of maximal ST depression was significantly smaller than that observed in the other 23 patients with angina pectoris ( 0.14 vs 0.23 mV on the average , p less than 0.05 ) . - pubmed
Combined live and inactivated poliovirus vaccine to control poliomyelitis in a developing country -- five years after . - pubmed
In patients older than 65 years operated on for senile cataracts , the male - to - female ratio was 1.8 with a female predominance . - pubmed
The mutagenic potency of each dye has been assessed by the Salmonella typhimurium / mammalian microsomal mutagenicity assay utilizing the TA100 and TA98 stains . - pubmed
Virulence and serum resistance of strain PAO1 were restored by curing of the entire plasmid R68.45 but not by deletions in the plasmid 's transfer gene regions . - pubmed
Effects of various agents on prednisolone - induced gastric lesions in rats . - pubmed
We studied the effects of various agents on prednisolone - induced gastric lesions in rats . - pubmed
Gastric lesions were produced by subcutaneous administration of 50 mg / kg of prednisolone once daily for 4 days to non - fasted rats . - pubmed
Among 50 geriatric inpatients ( average age 79 ) with late - onset epilepsy ( average duration two years ) , 28 had grand mal attacks , 12 had focal attacks , seven had both . - pubmed
The epilepsy followed cerebrovascular disease ( usually with hemiplegia ) in 21 patients ( 8 per cent of all our patients with hemiplegia in the two - year study period developed epilepsy ) . - pubmed
[ Electrocardiographic changes in patients with atherosclerotic psychoses treated with benzohexonium ] . - pubmed
Data are also reported of a clinico - statistical study on the frequency of side - effects with measles vaccination as well as of antibody response to it in 1542 children subdivided into different groups according to age and virus strain used ( Schwarz or Moraten ) . - pubmed
A patient from the Caribbean area with active T - cell lymphoma - leukaemia was primarily treated with deoxycoformycin ( DCF ) , 5 mg / m2 i.v . - pubmed
T - cell lymphoma - leukaemia has a bad prognosis with conventional anti - lymphoma therapy but was exquisitely sensitive to DCF in this patient . - pubmed
The histochemical characteristics of spontaneous hepatocellular neoplasms in mice of both sexes were examined and compared with those of hepatocellular neoplasms induced in female mice by administration of polycyclic aromatic hydrocarbon carcinogens as initiators with or without subsequent phenobarbitone treatment . - pubmed
Spontaneous neoplasms in the livers of mice rendered siderotic by subcutaneous iron injection were deficient in cellular accumulation of stainable iron . - pubmed
It is concluded that the histochemical characteristics of spontaneous or induced mouse hepatocellular neoplasms are variable and may be influenced by the inducing factors . - pubmed
Site of the ganglion blocking action of gardneramine and hirsutine in the dog urinary bladder in situ preparation . - pubmed
In both strains of rats immobilization stress induced a 2.3 - 3.3 - fold increase of PRA regardless of whether the animals had intact superior cervical ganglia . - pubmed
In both strains of rats SCGx resulted in depressed circulating aldosterone levels at all studied times after surgery . - pubmed
Thirteen patients with either Addison ' s disease , or Cushing ' s disease treated by bilateral adrenalectomy , were infused with the long - acting met - enkephalin analogue DAMME . - pubmed
Fifty - five patients , 28 male and 27 female , with congenital constriction band syndrome were reviewed . - pubmed
In the secondary prevention , it reduces the further incidence of sudden death in patients in whom administration is started in relatively small doses within a few weeks after acute myocardial infarction . - pubmed
[ Mechanism of the development of functional hyperemia in the palatal salivary glands of the rat ] . - pubmed
Thirty - eight patients with advanced or recurrent epithelial ovarian cancer no longer amenable to management with surgery , radiotherapy , or chemotherapy with known activity were given piperazinedione 9 mg / m2 intravenously every 3 weeks . - pubmed
Adverse effects consisted primarily of myelosuppression ( 81 % ) , nausea and vomiting ( 32 % ) , and azotemia ( 29 % ) with three patients ( 10 % ) having life - threatening thrombocytopenia . - pubmed
Ten randomly selected adults who had undergone orthodontic treatment and isolated superior repositioning of the maxilla for vertical maxillary excess ( VME ) were evaluated clinically and radiographically ( mean , 48.7 months postsurgery ) for signs and symptoms of masticatory and temporomandibular joint dysfunction . - pubmed
All patients were free of temporomandibular joint and masticatory muscle pain during function , upon contralateral masticatory loading , and upon palpation . - pubmed
In a double blind trial 60 patients were treated with a salicylic acid - containing product against warts ( Verrumal ) on basis fluorouracil in comparison to placebo . - pubmed
Chicken myoblasts were cultured from the pectoralis muscles of dystrophic and normal 11 - day - old embryos . - pubmed
Effects of cromakalim or glibenclamide on arrhythmias and dispersion of refractoriness in chronically infarcted in anesthetized dogs . - pubmed
Dogs were anaesthetised , subjected to an anterior - apical myocardial infarction , and allowed to recover . - pubmed
Only animals that did not have programmed electrical stimulation - inducible arrhythmias were used . - pubmed
Multinucleate cell angiohistiocytoma mainly affects middle - aged women , and usually presents as grouped reddish - brown papules . - pubmed
We report the successful use of the argon laser to treat two patients who had multinucleate cell angiohistiocytoma . - pubmed
We investigated the formation of a " nonthyroidal illness " ( NTI ) in pigs undergoing ventricular fibrillation ( VF ) and resuscitation . - pubmed
To increase awareness of this medically treatable condition , we present two patients who developed SMAS after sustaining severe brain injury . - pubmed
Arteriojugular oxygen difference ( AJDO2 ) is used to manage the care of acute head - injured patients by monitoring the relationship between cerebral metabolism and blood flow . - pubmed
The assay detected circulating antigen in 36 of 53 sera from Chinese schistosomiasis japonica patients , but not in sera from healthy persons or patients with paragonimiasis , trichinosis or cysticercosis . - pubmed
Aspirin toxicity in chicks given diets deficient in linoleic acid . - pubmed
In chicks fed LA - free diets , the ratio of 20:3n-9/20 : 4n-6 , which was used as an indicator of LA deficiency , was suppressed by aspirin treatment . - pubmed
In experiment 1 , horses were brought in from pasture 3 weeks before administration of 1 injection of TA ( 0.09 mg / kg of body weight , IM ) , and were stabled in dusty conditions throughout the experimental period . - pubmed
Seventy three patients with biliary tract obstruction due to a primary malignant tumor ( n = 60 ) , lymph node metastases at the porta hepatis ( n = 10 ) and benign stenosis of a biliary - enteric anastomosis ( n = 3 ) , were treated between 1985 and 1990 . - pubmed
Mortality was 30 % at 30 days in the group of patients with malignant diseases . - pubmed
To ascertain the prevalence and types of arrhythmias occurring after heart transplantation in children , all available 24 - hour ambulatory ECGs ( mean , 1.5 / patient ) , and 12 - lead surface ECGs ( mean , 27 / patient ) obtained from 59 orthotopic pediatric heart transplant recipients ( mean age , 9.7 + /- 5.9 years ) were examined . - pubmed
Of the 59 patients , 24 ( 41 % ) were found to have arrhythmias including chronic sinus tachycardia ( eight patients ) , sinus bradycardia ( four patients ) , supraventricular tachyarrhythmias ( nine patients ) , significant ventricular premature depolarization ( seven patients ) , and nonsustained ventricular tachyarrhythmias ( seven patients ) . - pubmed
Graft survival was significantly lower in those patients with arrhythmias as compared with the arrhythmia - free group ( 58 % versus 86 % , p = 0.02 ) . - pubmed
Interaction between the effects of 5 - hydroxytryptamine and adrenaline on the growth of platelet thrombi in the coronary artery of the anaesthetized dog . - pubmed
The interaction between adrenaline and 5 - hydroxytryptamine ( 5 - HT ) has been quantitated on the rate of thrombus formation , in the stenosed coronary artery with damaged endothelium of the anaesthetized dog . - pubmed
PURPOSE : The purpose of this study was to develop and validate an instrument for clinical trials to measure radiation - related acute morbidity and quality of life from the perspective of patients with head and neck cancer ( HNC ) treated with radiotherapy . - pubmed
METHODS : The Head and Neck Radiotherapy Questionnaire ( HNRQ ) was developed by a panel of health care workers and patients , was pretested in a pilot study of HNC patients , and was validated in a randomized double - blind trial of concomitant fluorouracil ( FUra ) infusional therapy ( 1.2 g / m2 per 24 hours ) or saline placebo administered for 72 hours in the first and third weeks of a 6 1/2 - week course of radiation therapy . - pubmed
CONCLUSION : The HNRQ is a valid measure of acute morbidity due to radiation therapy in patients with locally advanced HNC , and may be useful as an outcome measure for future clinical trials of radiation treatment strategies . - pubmed
Glutathione supplements protect preterm rabbits from oxidative lung injury . - pubmed
Animals assigned to oxygen had decreased lung volumes at 35 cmH2O , decreased lung compliance , increased edema , decreased cell viability , and decreased lung tissue and lavage - reduced / oxidized GSH levels , compared with control animals . - pubmed
These studies suggest that GSH supplementation maintains normal lavage and lung tissue GSH levels in preterm animals exposed to hyperoxia and attenuates the changes in lung mechanics associated with oxygen - induced lung injury . - pubmed
The metabolism of riboflavin in female patients with liver cirrhosis . - pubmed
The metabolism of vitamin B2 was studied in five female patients with liver cirrhosis of varying etiology . - pubmed
In conclusion , patients with liver cirrhosis of varying etiology and varying medical treatment did not show alterations of riboflavin turnover . - pubmed
Our experience in four patients operated on for metastases or different primary tumors demonstrated that this frontal approach may be safely used and allows minimal manipulation of the tumor . - pubmed
MRI of primary meningeal sarcomas in two children : differential diagnostic considerations . - pubmed
Meningeal sarcomas are very rare , highly aggressive tumours affecting children more frequently than adults . - pubmed
Glutamine and arginine metabolism in tumor - bearing rats receiving total parenteral nutrition . - pubmed
Since glutamine production is increased in catabolic states , these observations prompted us to investigate whether the flux of arginine to glutamine was increased in tumor - bearing ( TB ) rats , and we measured the synthesis rate of glutamine from arginine in control versus TB rats receiving standard total parenteral nutrition ( TPN ) solution . - pubmed
Male Donryu rats ( N = 36 ; body weight , 200 to 225 g ) were divided into two groups , control and TB rats . - pubmed
Yoshida sarcoma cells ( 1 x 10(6 ) ) were inoculated into the back of the rats ( n = 18 ) subcutaneously on day 0 . - pubmed
An increase in the flux rate of Arg to Gln was associated with an enhancement in the ratio of specific activity of ornithine to specific activity of arginine in TB rats ( control 51.5 % + /- 10.9 % v 77.4 % + /- 8.9 % , P & lt ; .05 ) . - pubmed
We conclude that ( 1 ) glutamine and arginine metabolism is altered with very small tumors , ( 2 ) although the flux of Arg to Gln was increased in TB and rats , the small increase in Arg to Gln can not explain the observed large increase in Gln production . - pubmed
We have assessed its effects on normal and malignant cells in preclinical animal models of localized and disseminated human hematopoietic neoplasms . - pubmed
Flavopiridol had a marked apoptotic effect documented by DNA nick - end labeling , or DNA agarose gels in xenografts of human hematopoietic tumors HL-60 , SUDHL-4 , and Nalm / 6 . - pubmed
This activity was manifested in our study as a potent antileukemia or antilymphoma effect in human tumor xenografts , which was dose and schedule dependent . - pubmed
These findings provide compelling evidence for the use of flavopiridol in human hematologic malignancies . - pubmed
We show the complications observed in a large series of children with hypomelanosis of Ito ( HI ) or incontinentia pigmenti achromians , studied in a neurology service over 30 years . - pubmed
Thirty - seven patients ( 49 % ) had seizures , consisting of infantile spasms in six cases ( 8 % ) . - pubmed
For this reason , we investigated for the presence and specificity of platelet and thyroid autoantibodies in 18 TAD patients with thrombocytopenia , 19 TAD patients without thrombocytopenia and in 22 patients with primary AITP without clinical signs of TAD . - pubmed
Thyroid autoantibodies were found in 89 % of patients with TAD and thrombocytopenia , in 95 % of patients with TAD without thrombocytopenia , and in 18 % of patients with primary AITP . - pubmed
Vibrio vulnificus is an opportunistic human pathogen causing wound infections and septicemia , characterized by hemorrhagic and edematous damage to the skin . - pubmed
BACKGROUND : Vascular access thrombosis accounts for at least $ 1 billion dollars in annual expenses and 25 % of hospitalizations for chronic hemodialysis patients . - pubmed
METHODS : Ninety - five accesses in 91 CHD patients were prospectively followed over 18 months . - pubmed
STUDY DESIGN : We retrospectively reviewed the protocol sheets of 503 consecutive patients with gastroesophageal reflux disease who underwent laparoscopic fundoplication over a period of 5 years . - pubmed
All pneumothoraces occurred in the first 100 patients . - pubmed
Five patients had significant operative bleeding ; two of them required laparotomy for bleeding control . - pubmed
Gastric ulcer was diagnosed in six patients . - pubmed
One alcoholic patient died of acute pancreatitis . - pubmed
Although human rights issues are often linked with AIDS issues abroad , in the US they receive insufficient attention in our response to women 's HIV risk . - pubmed
Diptericin 's submicromolar potency against Escherichia coli strains indicated that , in a manner similar to drosocin , the presence of the carbohydrate side chain is not necessary to kill bacteria . - pubmed
Neither the N - terminal , drosocin - analog fragment , nor the C - terminal , glycine - rich attacin - analog region was active against any of the bacterial strains studied , regardless of whether the Gal - GalNAc disaccharide units were attached . - pubmed
Mycobacterium leprae particle agglutination in diagnosis and monitoring of treatment of leprosy . - pubmed
leprae particle agglutination ( MLPA ) in 156 untreated leprosy patients . - pubmed
Seropositivities in control serum specimens were 11.3 per cent in active pulmonary tuberculosis patients , 2.6 per cent in dermatologic patients and 4.4 per cent in a healthy population , in low titers . - pubmed
Additionally , it provides an alternative tool in monitoring leprosy patients under MDT . - pubmed
The local control and biological relapse - free survival rates appear to be improved by high dose conformal radiotherapy from 20 to 30 % for patients with intermediate and high risk of relapse . - pubmed
The palladium may be stimulated in Parkinson ' s patients with major iatrogenic involuntary movements . - pubmed
A total of 60.9 % of the patients failed nonoperative management within 24 hours of admission ; 8 % failed 9 days or later after injury . - pubmed
Laparotomy was ultimately performed in 19.9 % of patients with small hemoperitoneum , 49.4 % of patients with moderate hemoperitoneum , and 72.6 % of patients with large hemoperitoneum . - pubmed
Analysis of infection of blood monocyte - derived macrophages by primary HIV strains shows that approximately one - third of 32 isolates was consistently high - replicating , one - third was consistently low - replicating , and one - third was dependent on the donor of the macrophages ( i.e. - pubmed
The location of this bottleneck in the HIV replication cycle differs according to viral strain and host - cell donor , but it was exerted before the stage of reverse transcription in 80 - 90 % of cases . - pubmed
For this , a susceptible bladder tumor line TCCSUP was treated with the inhibitory dose ( 50 microM ) of genistein for various periods of time , followed by mRNA isolations , cDNA probe preparations , and hybridization individually to cDNA chips containing 884 sequence - verified known human genes . - pubmed
METHODS : Five puppies had JPS performed with electrocauterization at 12 , 16 , 20 , 22 , and 24 weeks of age , respectively . - pubmed
The final mean AA in dogs that had JPS was 25 degrees greater than preoperative values ; 40 % increased over control . - pubmed
The final mean DI in dogs having JPS was 0.28 , 47 % improved over preoperative values and 58 % better than control . - pubmed
Mean pelvic dimensions in dogs that had JPS were 18 % less than control . - pubmed
CLINICAL SIGNIFICANCE : Dysplastic hips in young dogs were significantly improved by JPS . - pubmed
A non - significant reduction in incidence was observed for cryptococcosis by 45 % ( 0.81 vs. 0.45;P= 0.11 ) , oesophageal candidiasis by 29 % ( 3.34 vs. 2.39;P= 0.053 ) and mycobacterium avium complex by 18 % ( 1.58 vs. 1.29;P= 0.4 ) , and a non - significant increase was observed for tuberculosis by 17 % ( 0.62 vs. 0.73;P= 0.66 ) and non - Hodgkins lymphoma ( NHL ) by 51 % ( 0.43 vs. 0.65;P= 0.31 ) . - pubmed
In the acute study , obese rats received either vehicle ( water ) or irbesartan 1 hour before the experiment . - pubmed
RESULTS : In the presence of xanthurenic acid human lens epithelial cells undergo apoptosis - like cell death . - pubmed
BACKGROUND AND PURPOSE : Epidemiological studies have shown an increased risk of venous thrombosis in women taking third - generation oral contraceptives , ie , those containing the progestogens desogestrel or gestodene . - pubmed
Women with a first ischemic stroke were compared with control women without vascular diseases . - pubmed
All patients and control subjects filled in a questionnaire about the use of oral contraceptives and risk factors for ischemic stroke . - pubmed
RESULTS : Two hundred three women with an ischemic stroke and 925 control women were included . - pubmed
Functional visual loss in patients with bilateral ocular coloboma . - pubmed
The aim of this study was to investigate the pathological changes of the lateral pterygoid muscle ( LPM ) using magnetic resonance imaging ( MRI ) in patients with anterior disk displacement with nonreduction ( ADDnr ) of the temporomandibular joint ( TMJ ) and to compare the abnormal findings of the LPM with the clinical symptoms and other pathological MRI alterations of the TMJ . - pubmed
The results of this study indicate that the pathological changes of the LPM in TMJs with ADDnr could be detected by MRI and have a significant association with the main clinical symptoms of the patients . - pubmed
Our patient was a woman , old 78 years old who admitted for treatment of hypertrophic cardiomyopathy . - pubmed
At the same time , she had a urinary infection , caused by Escherichia coli , which confirmed possible relationship between primary biliary cirrhosis and occurrence of some Gramm negative bacteria , reported elsewhere . - pubmed
PATIENTS : Thirty - seven patients with schizophrenia . - pubmed
This induction may result in formation of neurotoxic metabolites , leading to increased AIMS scores and a higher frequency of tardive dyskinesia compared with patients without these alleles . - pubmed
We performed a tryptophan depletion ( TD ) test in 17 FM patients and 17 controls . - pubmed
Additionally pain perception was monitored in the FM patients . - pubmed
FM patients and controls exhibited a decrease of TRP and KYN during TD . - pubmed
5 - HIAA levels also decreased in all controls and in 11 FM patients , but showed a marked increase in 6 FM patients . - pubmed
Pain perception was not affected in the FM patients . - pubmed
These data demonstrate an altered TRP metabolism in a subgroup of FM patients , where the TD seems to activate 5 - HT metabolism . - pubmed
Intraarterial thrombolysis for perioperative stroke in patients undergoing cardiac operations . - pubmed
METHODOLOGY : In the past 4 years , 205 patients with non - small cell lung carcinoma ( NSCLC ) underwent surgical resection at Chiba Cancer Center , Chiba , Japan . - pubmed
Mucin production and composition is altered in dextran sulfate sodium - induced colitis in rats . - pubmed
BACKGROUND : The role of neoadjuvant chemotherapy for patients with multiple ( five or more ) bilobar hepatic metastases irrespective of initial resectability is still under scrutiny . - pubmed
METHODS : Retrospective data were collected from 71 patients after hepatectomy for five or more bilobar liver tumours . - pubmed
CONCLUSION : In patients with bilateral multiple colorectal liver metastases , neoadjuvant chemotherapy before hepatectomy was associated with improved survival and enabled complete resection with fewer extended hepatectomies . - pubmed
Despite the trauma of dissection and special metabolic requirements , the physiological properties of funiculi of the mammalian spinal cord can be studied in vitro . - pubmed
In the present study , we genotyped 121 Japanese patients with Parkinson ' s disease ( PD ) and 100 controls . - pubmed
Our results may help understand the mechanism that cause complications of levodopa therapy in PD patients . - pubmed
We report here a case of immune - mediated haemolytic anaemia associated to imatinib mesylate successfully treated with prednisone in a patient with CML . - pubmed
This case demonstrated that patients treated with imatinib mesylate can present immune - mediated haemolysis and adequate management of this event can be done maintaining the drug and associating corticosteroids . - pubmed
Retransplantation in patients with graft loss caused by polyoma virus nephropathy . - pubmed
The characteristics and outcome in 10 patients who underwent retransplantation after losing their renal grafts to BK virus - associated nephropathy ( BKAN ) are described . - pubmed
From this collective experience from five transplant centers ( although the follow - up after retransplantation was not extensive ) , it can be concluded that patients with graft loss caused by BKAN can safely undergo retransplantation . - pubmed
To clarify some of the circumstances in which this immune response can vary , we examine the immune - response profile of sheep protected against the clinical disease by prior vaccination with strain Rev. - pubmed
EXEGESIS : We reported a 45 year - old woman with distal lower limb lymphedema . - pubmed
Levodopa intake increases plasma levels of S - adenosylmethionine in treated patients with Parkinson disease . - pubmed
SAM caused Parkinson disease ( PD)-like symptoms in rodents . - pubmed
The objective of the study was to demonstrate an effect of acute levodopa intake on SAM synthesis in the plasma of treated PD patients . - pubmed
This is often observed in untreated PD patients who receive levodopa for the first time , or in more advanced , fluctuating PD patients , when they turn from the OFF to the ON phase . - pubmed
Because SAM in higher dosages may also counteract the antiparkinsonian efficacy of levodopa according to animal trials , this SAM increase may hypothetically contribute to the onset of wearing - off phenomena and other clinical signs of limited efficacy of levodopa during long - term treatment with levodopa in PD patients . - pubmed
Central nervous system - related permanent consequences in patients with Langerhans cell histiocytosis . - pubmed
PROCEDURE : In this single center study , 25 LCH patients observed for a median time of 10 years 3 months underwent a uniform thorough follow - up program including neuropsychological testing and electrophysiological evaluation . - pubmed
Intracranial abnormalities were the most frequent including diabetes insipidus ( DI ) in seven patients , anterior pituitary deficiencies in five patients , and neurodegenerative CNS disease in five patients . - pubmed
Brain stem evoked potentials showed abnormalities in four of nine tested patients , all of these four had neurodegeneration on MRI . - pubmed
Developing the sterile insect technique for Cryptophlebia leucotreta ( Lepidoptera : Tortricidae ): influence of radiation dose and release ratio on fruit damage and population growth in field cages . - pubmed
The effect of radiation dose and different release ratios of treated ( T ) to untreated ( U ) Cryptophlebia leucotreta ( Meyrick ) ( Lepidoptera : Tortricidae ) , on the incidence of fruit damage , the competitiveness of the treated males , and population growth was examined inside field cages . - pubmed
This study investigated the gender difference of HDLC levels in elderly Japanese patients with CAD . - pubmed
PATIENTS : A total of 163 elderly ( & gt ; or = 65 years ) outpatients with CAD ( 128 men aged 70.6+/-5.2 years and 35 women aged 74.1+/-6.0 years [ mean+/-SD ] ) were investigated . - pubmed
The AD 2 strain isolated from feces of a healthy dog in Slovakia was characterized phenotypically by the conventional tests and commercial identification kits API Staph and ID32 Staph . - pubmed
Results of biochemical tests identified the strain as S. - pubmed
In the goat , maternal hypophysectomy on Day 60 of gestation or treatment with 5 mg bromocriptine / day between Days 60 and 120 of gestation did not affect fetal body weights or the weights of the fetal adrenals , thyroid , pituitary gland or gonads when examined at 120 days gestation . - pubmed
In three rodent models of PAH , a 1 hour / day exposure to CO reverses established PAH and right ventricular hypertrophy , restoring right ventricular and pulmonary arterial pressures , as well as the pulmonary vascular architecture , to near normal . - pubmed
Value of fructosamine measurement in pregnant women with abnormal glucose tolerance . - pubmed
The aim of this study was to determine whether the level of serum fructosamine can be diagnostic for abnormal glucose tolerance in pregnant women . - pubmed
CONCLUSIONS : Fructosamine can be used to monitor the glucose level of pregnant women with abnormal glucose tolerance , and to identify the patients at high risk of abnormal glucose tolerance , but can not be used to predict gestational diabetes mellitus ( GDM ) in early stage of pregnancy . - pubmed
OBJECTIVE : To research the treatment effect of complex prescription of Chinese crude drug in BALB / c athymic mice with human liver cancer , which were built by Bel-7402 . - pubmed
RESULT : All of the 48 athymic mice survived 12 to 28 days ( Ms 24 days ) and every mouse with liver cancer demonstrated by dissection . - pubmed
Cardiotoxicity of Ma Huang / caffeine or ephedrine / caffeine in a rodent model system . - pubmed
When this syndrome of clinical signs emerged , animals were moribund sacrificed , and a histological analysis for heart lesions performed . - pubmed
Newer antidepressants should be considered as first - line agents for the treatment of depression in patients with and without cardiovascular disease . - pubmed
Periodic pharyngolaryngoscopy is recommended for curatively treated ESCC or BC patients . - pubmed
In 60 women undergoing vaginal hysterectomy , a total of 420 pain evaluations of postoperative pain intensity were performed by an observer and the patients . - pubmed
The patients themselves evaluated their pain on a visual analogue scale and on a 101 - point numerical rating scale . - pubmed
There was good agreement between pain intensity on the visual analogue scale and the 101 - point numerical rating scale in the patients ' self - assessment ( r ( 2)=0.74;y=0.81x+11.4 ) . - pubmed
The pain intensities determined by the observer on the visual analogue scale were markedly lower , on average than the patients ' self - report ( P<0.0001 ) . - pubmed
The pain intensities rated by the observer on the visual analogue scale were on averange 37.7 % of the patients ' self - assessments on the visual analogue scale . - pubmed
The purpose of this study was to determine differences in outcomes of patients with mucinous colorectal adenocarcinoma according to the type of mucin expressed . - pubmed
RESULTS : Of the 418 patients treated in this period , only 35 had a mucinous adenocarcinoma . - pubmed
Is screening for urinary porphobilinogen useful among patients with acute polyneuropathy or encephalopathy ? - pubmed
Porphyrin metabolites were screened in 108 patients with acute polyneuropathy or encephalopathy associated with pain and/or dysautonomia , who attended neurological wards , in order to evaluate the number of patients with acute porphyria . - pubmed
Surprisingly many patients ( 11 % ) had previously undiagnosed acute porphyria . - pubmed
Half of these patients had had mild to moderate symptoms of acute porphyria previously . - pubmed
Of the 108 patients studied , the levels of urinary porphyrins or their precursors were normal in the majority ( 79 % ) of the cases , who commonly had Guillain - Barre syndrome ( 40 % ) . - pubmed
Epileptic seizures were also frequent ( 18 % ) , but none of the patients with acute porphyria had solely epileptic seizures without prolonged confusion ( & gt;or= 1 day).Based on our findings , acute inherited porphyria is not infrequent among the selected group of neurological patients and screening of urinary PBG is cost - beneficial . - pubmed
Since the correct diagnosis of a hereditary disease is essential , genetic screening should be performed whenever possible for patients with clinically and biochemically confirmed acute porphyria . - pubmed
PET / CT and head - and - neck MRI are suggested for the initial staging of NPC patients . - pubmed
Central sleep apnea in patients with congestive heart failure . - pubmed
CLINICAL RELEVANCE : Straight anteriorization of the tibial tuberosity may be a useful adjunct for patients with medial articular defects of the patellar or trochlea in whom anteromedialization would be otherwise contraindicated . - pubmed
[ Opioids and cognition in patients with chronic pain : a systematic review ] . - pubmed
OBJECTIVE : The increasing use of opioids by patients suffering from chronic pain caused by different etiologies , and the possible effects of those substances on everyday activities , require careful evaluation of their effects . - pubmed
For this purpose , a systematic review was developed to assess the influence of opioids on the cognitive function in patients with chronic pain . - pubmed
The inclusion criteria were : clinical trials or case reports which included patients with chronic pain in treatment with opioids , cognitive assessment by specific tests and publication in English , Spanish or Portuguese . - pubmed
All better quality controlled trials did not show cognitive impairment of patients under opioid therapy . - pubmed
CONCLUSION : These results must be confirmed by additional randomized trials including a greater number of patients with chronic pain . - pubmed
Mycobacterium celatum pulmonary infection mimicking pulmonary tuberculosis in a patient with ankylosing spondylitis . - pubmed
Mycobacterium celatum , a slow - growing acid - fast bacillus , is an uncommon cause of human infection , mainly occurring in patients with AIDS . - pubmed
The literature was reviewed and clinical features of eight HIV - negative patients with M. - pubmed
Borna disease virus ( BDV ) is a neurotropic RNA virus that establishes non - cytolytic persistent infection in the central nervous system of warm - blooded animals . - pubmed
Depending on the host species and the route of infection , BDV persistence can modulate neuronal plasticity and animal behaviour and/or may provoke a T cell - mediated immunopathological reaction with high mortality . - pubmed
Therefore , BDV functions as a model pathogen to study persistent virus infection in the central nervous system . - pubmed
Progressive multifocal leukoencephalopathy in a patient with Good ' s syndrome . - pubmed
Herein we report the case of a 79 - year - old woman with GS who developed subacute motor deficits and cognitive changes . - pubmed
Polyoma virus JC , the agent of progressive multifocal encephalopathy ( PML ) , was identified in cerebrospinal fluid samples and brain biopsy specimens . - pubmed
OBJECTIVE : To explore an exercise method for the prevention and treatment of the patients with shoulder and back fasciitis . - pubmed
All the patients were followed up for 6 to 26 months , the recurrence were observed . - pubmed
RESULTS : After 3 weeks treatment , the scores of pain , sense of heaviness , strip sign , tenderness , shoulder and back function of the patients in two groups had significant differences compared with those before treatment ( all P & lt ; 0.01 ) . - pubmed
After treatment , the scores of pain , sense of heaviness , strip sign , tenderness , shoulder and back function of the patients in the treatment group were lower than those in the control group ( P & lt ; 0.05 ) . - pubmed
The development of oral squamous cell cancer ( OSCC ) is a multistep process involving the accumulation of multiple genetic alterations modulated by genetic pre - disposition and environmental influences such as tobacco and alcohol use , chronic inflammation , and viral infections . - pubmed
BACKGROUND : Uninterrupted use of ocular hypotensive medication by glaucoma patients is important to prevent vision loss , but medication persistence is poor . - pubmed
Transient cardiac ischaemia and abnormal variations in systemic blood pressure in unselected primary open angle glaucoma patients . - pubmed
PURPOSE : To investigate the relationship between the occurrence of transient cardiac ischaemic episodes and variations in the ambulatory 24 - h blood pressure and heart rate measurements in a group of unselected glaucoma patients . - pubmed
PARTICIPANTS : Twenty - four consecutive glaucoma patients and 23 age - matched controls were included in the present study . - pubmed
RESULTS : Overall , in glaucoma patients , LIE was also associated with a significant increase in diastolic and mean BP ( p = 0.007 and p = 0.003 respectively ) and HR ( p = 0.007 ) . - pubmed
However , six glaucoma patients ( 46.86 % ) failed to demonstrate any significant BP changes during the LIE ( p & gt ; 0.05 ) . - pubmed
CONCLUSIONS : As opposed to age - matched controls , in glaucoma patients the systemic circulatory responses associated with significant transient cardiac ischaemic events were highly variable . - pubmed
In North America , the indigenous groups have been identified as a population with increased risk of pneumococcal colonization and pneumococcal invasive disease . - pubmed
A total of 65 strains were isolated ; 11 % of the mothers and 69 % of the children carried S. - pubmed
[ Recurrent thromboses and hemorrhagic complications in patients with antiphospholipid syndrome during therapy with warfarin plus aspirin ] . - pubmed
SUBJECTS AND METHODS : Eighty - two patients diagnosed as having the antiphospholipid syndrome were examined . - pubmed
Hemorrhagic complications of antithrombotic therapy developed in 46.9 and 60.6 % of Groups 1 and 2 patients , respectively ( p = 0.26 ) . - pubmed
Beneficial effects of sodium or ethyl pyruvate after traumatic brain injury in the rat . - pubmed
Body composition assessed by the 4 - component model and association with lung function in 6 - 12 - y - old children with cystic fibrosis . - pubmed
BACKGROUND : Malnutrition is an indicator of a poor prognosis in patients with cystic fibrosis ( CF ) . - pubmed
OBJECTIVE : We measured BC by using the 4CM in 6 - 12 - y - old children with CF to 1 ) compare findings with those of healthy , matched control children and reference data ; 2 ) relate BC to lung spirometry [ forced expired volume in 1 s ( FEV1 ) ] ; and 3 ) compare findings with those from more commonly used 2CM techniques . - pubmed
DESIGN : One hundred clinically stable children with CF ( 57 % girls ) aged 6 - 12 y were measured by using the 4CM . - pubmed
Children with CF underwent spirometry ( FEV1 ) . - pubmed
They showed that ester hydrolysis and oxidation play predominant roles in mammalian metabolism of pyrethroids and that rapid metabolism leads to low mammalian toxicity . - pubmed
BACKGROUND : Fruits and vegetables are an essential part of the human diet , but many people do not consume the recommended serves to prevent cardiovascular disease and cancer . - pubmed
The biological characterization of ( 99m ) Tc - BnAO - NI as a SPECT probe for imaging hypoxia in a sarcoma - bearing mouse model . - pubmed
A biodistribution study after intravenous injection of ( 99m ) Tc - BnAO - NI in KHT sarcoma - implanted C3H mice was performed . - pubmed
The distribution of ( 99m ) Tc - BnAO - NI in KHT sarcoma - bearing mice revealed rapid clearance from the blood circulation . - pubmed
Importantly , mice inoculated with 4T1LMF4 and 4T1BM2 variants showed a 2.5- to 4 - fold increase in the incidence of spontaneous metastasis to bone compared to 4T1 tumor - bearing mice . - pubmed
This is the first report showing an absence of NSD in a human disease , revealing that this surveillance mechanism has exceptions in vivo . - pubmed
METHODS AND RESULTS : A catheter was implanted into the jugular vein of C57BL/6 mice to allow repeated administration of eritoran ( 5 mg / kg body weight ) or placebo . - pubmed
First , a group of articles was recently published on chemically instead of genetically induced MKD mouse and cell models , investigating the effects of several isoprenoid pathway intermediates . - pubmed
Metallofullerene - based nanoplatform for brain tumor brachytherapy and longitudinal imaging in a murine orthotopic xenograft model . - pubmed
Human glioblastoma U87MG cells were implanted by using stereotactic procedures into the brains of 37 female athymic nude - Foxn1nu mice and allowed to develop into a tumor for 8 days . - pubmed
Survival studies involved 20 mice that received infusion of a nanoplatform by means of convection - enhanced delivery ( CED ) 8 days after tumor implantation . - pubmed
PARTICIPANTS : Patients with acute stroke given intravenous thrombolytic therapy between 6 September 2007 and 1 October 2010 . - pubmed
After review in person , the stroke specialist tended to treat patients with a higher median modified Rankin Scale ( 1 vs 0 by telephone ) . - pubmed
MATERIAL AND METHOD : Between 1.1.2004 and 31.12.2005 we treated 71 patients with 102 idiopathic clubfeet with the Ponseti method . - pubmed
endemicum ) , Treponema paraluiscuniculi , and the unclassified Fribourg - Blanc treponeme cause clinically distinct diseases , these pathogens are genetically and antigenically highly related and are able to cause persistent infection . - pubmed
endemicum isolate ( Iraq B ) , the unclassified Fribourg - Blanc isolate , and the Cuniculi A strain of T. - pubmed
We investigated the influence of the lateral prefrontal cortex ( PFC ) in a response inhibition task by using cognitive electrophysiology in prefrontal lesion patients . - pubmed
Therapeutic strategies for patients with micropenis or penile dysmorphic disorder . - pubmed
Corrective surgery for micropenis can be performed in patients with realistic expectations . - pubmed
BACKGROUND : Intra - articular corticosteroid injections are a safe and effective treatment for patients with juvenile idiopathic arthritis . - pubmed
OBJECTIVE : The purpose of this study was to report the spectrum of care , technique and safety of ultrasound - guided corticosteroid injection therapy in patients with juvenile idiopathic arthritis and to propose an age - weight - joint - based corticosteroid dose protocol . - pubmed
MATERIALS AND METHODS : A retrospective analysis was performed of 198 patients ( ages 21 months to 28 years ) referred for treatment of juvenile idiopathic arthritis with corticosteroid therapy . - pubmed
An age - weight - joint - based corticosteroid dose protocol is effective and integral to interdisciplinary care of patients with juvenile idiopathic arthritis . - pubmed
442 asthmatic children and 191 controls were genotyped by RFLP . - pubmed
We performed a multicentric , prospective , and nonrandomized trial from July 2008 to July 2009 , wherein 2 groups of patients with prolapse and hemorrhoids were treated with a single PPH or a D - PPH . - pubmed
The primary outcome was evaluation of safety and efficacy of the D - PPH procedure in selected patients with large hemorrhoidal prolapse . - pubmed
RESULTS : In all , 281 consecutive patients suffering from hemorrhoidal prolapse underwent surgery , of whom 74 were assigned intraoperatively to D - PPH , whereas 207 underwent single PPH . - pubmed
CONCLUSIONS : Our data support the hypothesis that an accurate intraoperative patient selection for single ( PPH ) or double ( D - PPH ) stapled technique will lower in a significant way the incidence of recurrence after Longo 's procedure for hemorrhoidal prolapse . - pubmed
In this double - blinded , placebo - controlled , randomized trial , a total of 74 healthy middle - aged overweight women ( 25 & lt;= BMI & lt;= 30 kg / m(2 ) ) received either 250 mg magnesium in the form of magnesium oxide or placebo daily for 8 weeks . - pubmed
We have recently reported a long - lasting decrease in circulating gammadelta T cells in osteoporotic patients on oral amino - bisphosphonates ( N - BPs ) . - pubmed
Subjects with mild ( Child - Pugh A , Group A , n=8 ) and moderate ( Child - Pugh B , Group B , n=9 ) liver impairment and subjects with normal liver function ( Group DA and DB , both n=9 ) received a dose of 100 mg almorexant . - pubmed
No reliable animal model is available for studying keloids . - pubmed
PARTICIPANTS : Keloid fibroblasts were received from the Baylor College of Medicine , and additional keloid fibroblasts were enzymatically isolated from the dermal layer of lesions removed from consenting patients at The Johns Hopkins Hospital . - pubmed
( 2 ) As there are differences between pharmacokinetic processes in the normal and pathological states , how to express characteristic " syndromes " in an animal model ? - pubmed
Candida glabrata cells suspended in water are under hypo - osmotic stress and undergo cell death in 1 - 2 days , unless they are at a density of more than 10(5 ) CFU mL(-1 ) . - pubmed
[ Effects of XELOX regimen as neoadjuvant chemotherapy on radical resection rate and prognosis in patients with advanced gastric cancer ] . - pubmed
OBJECTIVE : The purpose of this study was to investigate the efficacy and mechanism of oxaliplatin in combination with capecitabine ( XELOX ) regimen as neoadjuvant chemotherapy in the treatment of patients with advanced gastric cancer . - pubmed
METHODS : Eighty - five patients with advanced gastric cancer ( stage IIB and IIIC ) were randomly divided into two groups : neoadjuvant chemotherapy group ( 40 cases ) and surgery alone group ( 45 cases ) . - pubmed
In the surgery alone group , patients directly received radical resection of gastric cancer . - pubmed
CONCLUSIONS : XELOX regimen as neoadjuvant chemotherapy in the treatment of patients with advanced gastric cancer can effectively improve the R0 resection rate and prolong the survival time of the patients . - pubmed
Evaluation of aldosterone concentrations in dogs with hypoadrenocorticism . - pubmed
BACKGROUND : Some dogs with primary hypoadrenocorticism ( HA ) have normal sodium and potassium concentrations , a phenomenon called atypical Addison ' s disease . - pubmed
The assumption that the zona glomerulosa and aldosterone secretion in these dogs are normal seems widely accepted ; however , aldosterone measurements are missing in most published cases . - pubmed
ANIMALS : Seventy dogs with HA , 22 dogs with diseases mimicking HA , and 19 healthy dogs . - pubmed
Aldosterone was low or undetectable in 67/70 dogs with HA independently of sodium and potassium levels . - pubmed
CONCLUSION AND CLINICAL IMPORTANCE : Cortisol and aldosterone secretion is compromised in dogs with HA with and without electrolyte abnormalities . - pubmed
The term atypical Addison ' s disease , used for dogs with primary HA and normal electrolytes , must be reconsidered ; other mechanisms allowing normal electrolyte balance without aldosterone should be evaluated in these dogs . - pubmed
Black disease is an acute disease of sheep and cattle . - pubmed
In this work , artificial spiking of down - scaled models for the manufacturing process of an inactivated pandemic influenza virus vaccine were used to investigate inactivation of PCV1 and the physico - chemically related porcine parvovirus ( PPV ) by formalin and ultraviolet - C ( UV - C ) treatment as well as removal by the purification step sucrose gradient ultracentrifugation . - pubmed
Still , the inactivated pandemic influenza vaccine manufacturing process provides for robust virus reduction , in addition to the already implemented testing for PCV1 to avoid any contaminations . - pubmed
OBJECTIVE : To determine the effect of placental abruption on the outcome of infants born between 22 and 26 weeks of gestation . - pubmed
Effects of yoga training in patients with chronic obstructive pulmonary disease : a systematic review and meta - analysis . - pubmed
CONCLUSIONS : The current limited evidence suggested that yoga training has a positive effect on improving lung function and exercise capacity and could be used as an adjunct pulmonary rehabilitation program in COPD patients . - pubmed
METHODS : Prospective observational cohort of adult patients admitted to a Level I Trauma Center within 6 h of injury . - pubmed
Group 1 patients had the lowest incidence of coagulopathy and disseminated intravascular coagulopathy , and in general presented with better coagulation profile measured by either classic coagulation tests , thromboelastography or clotting factors . - pubmed
Isolated severe TBI was not an independent risk factor for the development of coagulopathy ( OR 1.06 ; 0.35 - 3.22 CI , p = 0.92 ) , however , isolated severe TBI patients who developed coagulopathy had higher mortality rates than isolated severe TBI patients without coagulopathy ( 66 vs. 16.6 % , p & lt ; 0.05 ) . - pubmed
However , severe TBI patients who develop coagulopathy have extremely high mortality rates . - pubmed
Remote magnetic navigation for persistent atrial fibrillation ablation via a retrograde aortic access : an approach for patients after atrial septal defect device closure . - pubmed
Patterns of conservation in the evolution of the glycogen / starch branching and debranching enzymes hint at some as yet unknown mechanisms , as mutations disrupting these patterns lead to a variety of genetic diseases in humans and other mammals . - pubmed
Grass pollen sublingual immunotherapy : a double - blind , placebo - controlled study in elderly patients with seasonal allergic rhinitis . - pubmed
BACKGROUND : This study evaluates the safety and efficacy of specific sublingual immunotherapy ( SLIT ) against grass pollen allergens in patients & gt;60 years of age with seasonal allergic rhinitis ( SAR ) and/or asthma . - pubmed
CONCLUSIONS : SLIT in elderly patients with a grass pollen allergy generated a significant clinical improvement in the active group compared with the placebo group for grass pollen season . - pubmed
Detection of RHDV strains in the Iberian hare ( Lepus granatensis ): earliest evidence of rabbit lagovirus cross - species infection . - pubmed
Although a related virus severely affects hares , cross - species infection was only recently described for new variant RHDV in Cape hares ( Lepus capensis mediterraneus ) . - pubmed
We sequenced two strains from dead Iberian hares ( Lepus granatensis ) collected in the 1990s in Portugal . - pubmed
This is the earliest evidence of RHDV affecting a species other than European rabbits . - pubmed
We have thus excluded peripheral contributions by using an animal model of early conductive hearing loss ( CHL ) that provides auditory deprivation but does not induce cochlear damage . - pubmed
Beneficial effect of an omega-6 PUFA - rich diet in non - steroidal anti - inflammatory drug - induced mucosal damage in the murine small intestine . - pubmed
The mucosal damage induced by indomethacin was significantly lower in mice fed the safflower oil diet than in mice fed the beef tallow or fish oil diet ( P & lt ; 0.05 ) . - pubmed
MATERIALS AND METHODS : A total of 64 anaesthetized patients with paralysis were enrolled in a single - blind , randomized control trial to be intubated with one of the devices . - pubmed
CONCLUSION : In individuals with non - specific LBP and reduced hip rotation , clinical intervention of providing exercises targeted at the hip can be beneficial in improving pain and function , with strengthening exercises most beneficial for improving function . - pubmed
The last few years have seen a dramatic improvement in the management of this tumor as nearly 50 - 70 % of selected patients with early HCC survive for a median period of up to 5 years after liver transplantation , resection or local ablation . - pubmed
Short tandem repeats ( STRs ) are implicated in dozens of human genetic diseases and contribute significantly to genome variation and instability . - pubmed
The selected studies involved a total of 871 stroke subjects . - pubmed
A 36 - year old man presented with a 1 - year history of progressive unsteadiness . - pubmed
Hybrid wound dressings with controlled release of antibiotics : Structure - release profile effects and in vivo study in a guinea pig burn model . - pubmed
The latter was tested on a guinea pig burn model , compared to the neutral non - adherent dressing material Melolin ( Smith & amp ; Nephew ) and Aquacel Ag ( ConvaTec ) . - pubmed
We retrospectively reviewed data , including preoperative ultrasonography and/or computed tomography results , on patients who underwent total thyroidectomy for thyroid cancer at our hospital between 2006 and 2012 . - pubmed
Sixty - eight patients had papillary thyroid cancer , and 30 had follicular cancer . - pubmed
Identification of lymph node involvement during preoperative radiologic investigations was strongly prognostic for recurrence : 35.3 % of patients with positive preoperative ultrasonography findings and 62.5 % of those with positive preoperative computed tomography findings had recurrence ( p = 0.01 ) . - pubmed
Wound - healing potential of the fruit extract of Phaleria macrocarpa . - pubmed
Experimentally , two - centimeter - wide full - thickness - deep skin excision wounds were created on the posterior neck area of the rats . - pubmed
The wounds were topically treated with gum acacia as a vehicle in the control group , intrasite gel in the reference group , and 100 and 200 mg / mL P. - pubmed
Norovirus GII ( AF 5 2 % , 95 % CI 3 0 - 7 1 ) , rotavirus ( 4 8 % , 4 5 - 5 0 ) , Campylobacter spp ( 3 5 % , 0 4 - 6 3 ) , astrovirus ( 2 7 % , 2 2 - 3 1 ) , and Cryptosporidium spp ( 2 0 % , 1 3 - 2 6 ) exhibited the highest attributable burdens of diarrhoea in the first year of life . - pubmed
AIMS : The high HIV / AIDS burden in Sub - Saharan Africa has led to cryptococcosis becoming a public health concern . - pubmed
RESULTS : The intraspecific variation between tested strains allowed for their delineation into three traditional varieties of C. - pubmed
A 62 - year - old woman presented to our hospital with a 1 - week history of progressive dyspnea and difficulty in walking . - pubmed
CT imaging findings in patients with advanced hepatocellular carcinoma treated with sorafenib : Alternative response criteria ( Choi , European Association for the Study of the Liver , and modified Response Evaluation Criteria in Solid Tumor ( mRECIST ) ) versus RECIST 1.1 . - pubmed
MATERIALS AND METHODS : This retrospective study included 60 patients with advanced HCC treated with sorafenib . - pubmed
CONCLUSION : This study found a significant difference between Choi versus RECIST 1.1 , mRECIST and EASL when evaluating the response to sorafenib in HCC patients . - pubmed
In 735 patients with a current episode of major depression and 456 never - depressed control participants pain thresholds ( pressure pain thresholds , PPTs ) were measured at the index finger pad and self - rated suprathreshold pain intensity ratings were obtained using the Pain Sensitivity Questionnaire ( PSQ)-minor subscore , an instrument that assesses pain intensity in daily life situations . - pubmed
BACKGROUND : Older adults have the highest rates of hospitalization and mortality from traumatic brain injury ( TBI ) , yet outcomes in this population are not well studied . - pubmed
OBJECTIVE : Children with Down syndrome ( DS ) have a high incidence of middle ear disorders and congenital abnormalities of the external , middle and inner ear . - pubmed
The aim of the present study was to compare the WAI measurements of children with DS with those of typically developing , normal - hearing children according to their tympanometric findings . - pubmed
METHODS : Four groups of children with Down syndrome ( age range : 2 years and 4 months to 16 years and 3 months ; mean age : 8.5 yr ) with normal tympanograms ( 19 ears ) , flat tympanograms ( 13 ears ) , mild negative pressure tympanograms ( 6 ears between -100 and -199 daPa at the admittance peak ) and severe negative pressure tympanograms ( 4 ears at -200 daPa or lower at the admittance peak ) were assessed . - pubmed
METHODS : We performed an observational cohort study on adult trauma patients ( & gt;=18 years ) , who required admission to the intensive care unit and who survived hospitalization between 1997 and 2011 . - pubmed
METHOD : The efficacy of sequential treatment for nineteen vertical semicircular canal S - BPPV patients(Group A ) and forty - five vertical semicircular canal O - BPPV patients(Group B ) who were admitted to our hospital between January 2014 and July 2015 was retrospectively analyzed and compared , treatment of five cases with horizontal semicircular canal S - BPPV was reported here as well . - pubmed
Hypolipidemic effects of HVC1 in a high cholesterol diet - induced rat model of hyperlipidemia . - pubmed
HVC1 , a novel formation containing four herbs , was developed and its hypolipidemic effects in rats with high cholesterol diet ( HCD)-induced hyperlipidemia were investigated . - pubmed
In particular , moderate CR in humans ameliorates multiple metabolic and hormonal factors that are implicated in the pathogenesis of type 2 diabetes , cardiovascular diseases , and cancer , the leading causes of morbidity , disability and mortality . - pubmed
Over a period of 8 consecutive years , a retrospective chart review was performed of 105 patients who underwent robotic - assisted surgery for benign esophageal diseases by a single surgeon . - pubmed
Abnormal regional spontaneous neuronal activity associated with symptom severity in treatment - naive patients with obsessive - compulsive disorder revealed by resting - state functional MRI . - pubmed
In this current study , we aimed to investigate cerebral regions with abnormal spontaneous activity using resting - state functional magnetic resonance imaging ( fMRI ) and further explored the relationship between the spontaneous neuronal activity and symptom severity of patients with OCD . - pubmed
Thirty - one patients with OCD and 32 age - and sex - matched normal controls received the fMRI scans and fractional amplitude of low - frequency fluctuation ( fALFF ) approach was applied to identify the abnormal brain activity . - pubmed
We found that patients with OCD showed decreased fALFF not only in the cortical - striato - thalamo - cortical ( CSTC ) circuits like the thalamus , but also in other cerebral systems like the cerebellum , the parietal cortex and the temporal cortex . - pubmed
Effect of Androgen on Normal Biodistribution of [ 18F ]- 2 '- Fluoro-5 - methyl-1 - beta - D - arabinofuranosyluracil ( 18F - FMAU ) in Athymic Non - tumor - bearing Male Mice . - pubmed
MATERIALS AND METHODS : Non - castrated ( n=4 ) and castrated ( n=4 ) athymic non - tumor - bearing male mice served as models for presence and absence , respectively , of androgen . - pubmed
The hepatitis E virus ( HEV ) is a major cause of acute hepatitis globally . - pubmed
In addition , these isolated compounds were assessed for antimicrobial activity including antimalarial ( against Plasmodium falciparum , K-1 strain ) , antifungal ( against Candida albicans ) , antibacterial ( against Bacillus cereus ) activities . - pubmed
BACKGROUND : Nab - paclitaxel plus gemcitabine has become a standard treatment regimen in patients with metastatic pancreatic adenocarcinoma ; however , retrospective data suggest that gemcitabine might be inefficient in 50 - 60 % of patients and thus not an optimum regimen in combination with nab - paclitaxel . - pubmed
Eligible participants were previously untreated patients with metastatic pancreatic adenocarcinoma ( previous adjuvant chemotherapy after curative intent resection was allowed if the interval between the end of chemotherapy and relapse was more than 12 months ) . - pubmed
Patients continued treatment until unacceptable toxicity , disease progression , or patient withdrawal . - pubmed
At 4 months , 40 ( 56 % , 90 % CI 45 - 66 ) of 72 patients in the leucovorin and fluorouracil group were alive and free from disease progression ( 21 [ 54 % , 40 - 68 ] of 39 patients in the gemcitabine group were also alive and progression - free at 4 months ) . - pubmed
Forty patients with high - grade gliomas and 44 with metastases were enrolled in this study . - pubmed
Thirty - five patients with high - grade glioma and 30 patients with metastases had FLAIR images . - pubmed
After the publication of results from the National Institute of Health - sponsored Trial to Assess Chelation Therapy ( TACT ) , a randomized controlled trial ( RCT ) in patients after myocardial infarction ( MI ) , there is a renewed interest in clarifying the role of this treatment modality for patients with coronary artery disease . - pubmed
Atopy as a risk factor for subclinical hypothyroidism development in children . - pubmed
METHODS : We enrolled 620 allergic children ( 1.11 - 12.8 years ) consecutively attending to our department . - pubmed
Results : Forty patients ( 15 women and 25 men ; median age , 44 years [ range , 22 - 72 years ] ) were enrolled , including 29 patients ( 73 % ) with GBS ( 90 % Brighton level 1 certainty ) , 7 ( 18 % ) with encephalitis , 3 ( 8 % ) with transverse myelitis , and 1 ( 3 % ) with newly diagnosed chronic inflammatory demyelinating polyneuropathy . - pubmed
Of these , 35 patients ( 88 % ) had molecular and/or serologic evidence of recent ZIKV infection in the serum and/or cerebrospinal fluid . - pubmed
Of the patients positive for ZIKV infection , 27 had GBS ( 18 demyelinating , 8 axonal , and 1 Miller Fisher syndrome ) , 5 had encephalitis ( 3 with concomitant acute neuromuscular disease ) , 2 had transverse myelitis , and 1 had chronic inflammatory demyelinating polyneuropathy . - pubmed
Admission to the intensive care unit was required for 9 patients positive for ZIKV infection ( 26 % ) , and 5 ( 14 % ) required mechanical ventilation . - pubmed
At 3 months , 2 patients positive for ZIKV infection ( 6 % ) died ( 1 with GBS and 1 with encephalitis ) , 18 ( 51 % ) had chronic pain , and the median modified Rankin score among survivors was 2 ( range , 0 - 5 ) . - pubmed
Adherence and feasibility of 2 treatment schedules of S-1 as adjuvant chemotherapy for patients with completely resected advanced lung cancer : a multicenter randomized controlled trial . - pubmed
BACKGROUND : We conducted a multicenter randomized study of adjuvant S-1 administration schedules for surgically treated pathological stage IB - IIIA non - small cell lung cancer patients . - pubmed
METHODS : This is a retrospective case - control cohort study , comprised of PCOS women ( N=29 ) and normal menstruating women as controls ( N=20 ) . - pubmed
RESULTS : PCOS women showed reduced plasma NOx(nitrate+nitrite ) and H2O2 compared to controls . - pubmed
H2O2 concentration in PCOS women was also found to be reduced . - pubmed
Head and neck cancer patients treated with irradiation often present irreversible salivary gland hypofunction for which no conventional treatment exists . - pubmed
MiR-186 inhibits cell proliferation and invasion in human cutaneous malignant melanoma . - pubmed
The purpose of this study was to investigate the expression level and functional role of miR-186 in human cutaneous malignant melanoma cells . - pubmed
Conclusions : Our findings suggested that miR-186 exhibit an inhibitory effect on CMM cell proliferation , migration , and invasion ; thus , may serve as a potential therapeutic target for human CMM intervention . - pubmed
Physical Disabilities Related to the Depressive Mental States of Japanese Patients with Subacute Myelo - optico - neuropathy . - pubmed
Objective The aim of this study was to clarify the clinical conditions related to the depressive mental states in Japanese patients with subacute myelo - optico - neuropathy ( SMON ) , caused by clioquinol intoxication more than 40 years previously . - pubmed
Repeating mental supportive interviews and medical examinations by experts helped to improve the depressive mental state and revealed close relationship between the mental state and the physical disabilities of the SMON patients . - pubmed
All of the subjects received amblyopic treatment and were divided into 2 groups after 6 months of follow - up : the recovered amblyopic group with a best - corrected visual acuity ( BCVA ) & gt;=0.8 and the persistent amblyopic group with a BCVA & lt;0.8 on the Landolt C chart . - pubmed
Results : Forty - four amblyopic children were included , of which 26 were in the recovered amblyopic group after 6 months of follow - up . - pubmed
The patients with strabismic anisometropic amblyopia and severe amblyopia ( initial VA & lt;= 0.3 ) were significantly predisposed to developing persistent amblyopia ( P=0.049 and P & lt ; 0.001 , respectively ) . - pubmed
We identified a strong correlation between the presence of dilated ovarian veins and chronic pelvic pain in premenopausal parous patients with hematuria . - pubmed
INTRODUCTION : Most patients ( & gt;70 % ) experience acute neuropathic symptoms shortly after oxaliplatin infusions . - pubmed
Overall , 30%-50 % of patients suffer from chronic oxaliplatin - induced peripheral neuropathy ( OIPN ) . - pubmed
In animals , there is a beneficial effect on sensorimotor and pain disorders , as well as related comorbidities , after repeated administration of oxaliplatin . - pubmed
Patients with colorectal cancer and initiating adjuvant oxaliplatin - based chemotherapy are eligible . - pubmed
A 31 - year - old man with mild hemophilia B developed a herniated disc treated with prednisolone for back pain . - pubmed
The respective antibacterial activity of the oils was tested against four bacterial strains : two Gram - positive strains , Staphylococcus aureus ( ATCC 25923 ) and Bacillus licheniformis ( ATCC12759 ) , and two Gram - negative strains , Escherichia coli ( ATCC25922 ) and Klebsiella pneumoniae ( ATCC 13883 ) . - pubmed
[ Commercially Communicable Diseases and patients with hepatitis C virus ] . - pubmed
This allows us to speed up simulations for in vivo trials , where we obtained peak - to - valley dose ratios of 1.20 + - 0.05 and 6.1 + - 0.2 for proton minibeam irradiations targeting the tumour and crossing the rat head . - pubmed
METHODS : We prospectively calculated FRAX score for hip and major osteoporotic fractures in inflammatory bowel disease patients consecutively recruited . - pubmed
RESULTS : The mean risk of hip fractures at 10 years , for the 80 recruited patients , resulted 1.4 % , while the mean risk of major osteoporotic fractures was 7.8 % . - pubmed
In a small subset of 8 individuals , a higher relative abundance of Akkermansia muciniphila was correlated with type 2 diabetes remission . - pubmed
These findings could be of particular relevance for future functional studies assessing the effects of cannabinoids in horses to manage pain . - pubmed
We present a patient with a spinocerebellar ataxia ( SCA)-like phenotype who was found to carry an M233V mutation . - pubmed
A 26 - year - old man of an Azerbaijani origin presented with a progressive impairment of coordination followed by memory impairment . - pubmed
Given reported promising results of open - label fecal microbiota transplantation ( FMT ) therapy in patients with predominant abdominal bloating , we studied efficacy of this treatment in a randomized , placebo - controlled trial . - pubmed
METHODS : Patients with refractory IBS , defined as failure of > = 3 conventional therapies , were randomly assigned to single - dose nasojejunal administration of donor stools ( n=43 ) or autologous stools ( n=19 ) in a double - blind study , performed from December 2015 through October 2017 , and followed for 1 year . - pubmed
CONCLUSIONS : In a randomized trial of patients with treatment - refractory IBS with predominant bloating , FMT relieved symptoms compared with placebo ( autologous transplant ) , although effects decreased over 1 year . - pubmed
METHODS : Fifteen patients with intracranial arterial stenosis were prospectively enrolled 6 - 8 months after stenting . - pubmed
RESULTS : During the follow - up period , the WeChat platform was used to refer 8 children with respiratory infection symptoms to local hospitals for treatment . - pubmed
Although there are effective treatments available for many , probably most , patients with OCD , a significant number do not respond , or fail to experience a sustained beneficial response . - pubmed
For patients with such chronic , disabling and ' treatment - refractory ' OCD , neurosurgical treatments may be considered . - pubmed
CASE : Seven years after hip arthroscopy for cam impingement , a 47 - year - old female patient suffered a valgus impacted femoral neck fracture of her left hip that was stabilized with cannulated screws . - pubmed
Primary hepatic tumors developed in 13 young women who had been ingesting contraceptive steroids . - pubmed
Benign tumors were successfully resected in eight women . - pubmed
One woman died during hepatic resection for malignant hepatoma ; in two other cases of hepatocellular carcinoma , tumors were nonresectable . - pubmed
In two patients , the tumor was left in situ after neoplasm had been excluded by biopsy . - pubmed
A patient with severe alcoholic liver disease , in whom there was almost complete suppression of function of the reticuloendothelial system of the liver as noted on a 99mTc - SC scan is discussed . - pubmed
A study of total sleep deprivation for one night was performed on 12 patients with endogenic depression and 10 with neurotic depression , as well as a control group of 10 normals . - pubmed
Fracture of the frontal sinus in children . - pubmed
Two juvenile patients , ages 5 and 8 , had traumatic fractures of the frontal sinus that included involvement of the nasal - frontal ducts and posterior tables . - pubmed
22 patients suffering from acute myocardial infarction were subjected to daily blood sampling for up to 6 days after admission to hospital . - pubmed
5 patients with myocardial ischaemia and chest pain , but no evidence of infarction , were similarly investigated as controls . - pubmed
Infarction patients were divided into three clinical groups : uncomplicated cases , complicated and fatalities . - pubmed
Four cases ( 3 children and one adolescent ) are presented in which Parinaud ' s syndrome developed in the course of progressive non - tumorous hydrocephalus . - pubmed
Retinal arterioles in the New Zealand strain of genetically hypertensive rats . - pubmed
Reduction of the ( expanded ) body fluid volumes found in some patients with renal hypertension may be essential in the management of these cases . - pubmed
The combined effect of salt depletion ( which increases PRA ) and beta - adrenergic blockade with propranolol ( during which treatment PRA is lowered ) was systematically studied in 3 groups of hypertensive patients ( including one group with chronic renal insufficiency ) . - pubmed
Once frank rupture has occurred , the outlook is grave , but immediate surgery and intensive general care can allow survival in up to 50 % of patients . - pubmed
Alterations in electroencephalogram activity were not observed in urethane anaesthetized animals , whereas 50 % of Hypnorm anaesthetized animals exhibited epileptic activity . - pubmed
induced epileptic activity in a majority of animals anaesthetized using urethane . - pubmed
Fifty - six patients ( 60 testes ) who were previously treated with chemotherapy for metastatic germ cell neoplasm ( originally diagnosed by removal of the contralateral testis or by biopsy of metastatic disease ) underwent sonography followed by orchiectomy . - pubmed
These results suggest the potential for predicting the pathologic diagnosis in some patients after receiving chemotherapy for germ cell neoplasm . - pubmed
Immunohistochemical study of glial reaction and serum - protein extravasation in relation to neuronal damage in rat hippocampus after ischemia . - pubmed
Transient forebrain ischemia of 30 min duration was produced in anaesthetized rats by four - vessel occlusion . - pubmed
Between 1962 and 1983 , fourteen patients ( twenty knees ) had centralization of the fibula for congenital longitudinal deficiency : tibial , complete . - pubmed
Attempts to reconstruct the knee joint by centralization of the fibula are not warranted for patients who have congenital longitudinal deficiency : tibial , complete . - pubmed
The models in rats included " learned helplessness , " shock - suppressed licking ( Vogel conflict test ) and forced swimming - induced immobility ( " behavioral despair " ) . - pubmed
The models in mice included shock - suppressed exploration ( four plates test ) , spontaneous exploration ( staircase test ) and food consumption in a novel situation ( emotional hypophagia ) . - pubmed
Further tests in rats examined the effects of EGB 761 on memory ( passive avoidance test ) and responsiveness to shock to determine whether the preventive effects observed with EGB 761 in the learned helplessness procedure were due either to drug - induced impairment of memory or to reduced shock sensitivity . - pubmed
EGB 761 did not affect performance in the passive avoidance task or alter the animals ' response to electric shock , suggesting that the effects observed in the learned helplessness procedure were not due to impaired memory or reduced shock sensitivity . - pubmed
Anxiolytic - like activity was also seen in the emotional hypophagia test in mice where repeated administration of EGB 761 increased the amount of food consumed. - pubmed
DESIGN : Prospective notification of patients reaching a defined level of advanced chronic renal failure ( serum creatinine concentration greater than or equal to 500 mumol / l or blood urea concentration greater than or equal to 25 mmol / l ) within one year and follow up for at least three , and , at most , four years after notification . - pubmed
Fourteen patients with symptoms of vertebrobasilar insufficiency caused by vertebral artery stenosis in the distal first portion underwent surgical reconstruction . - pubmed
[ Behavior of blood pressure in 3 shift work of workers with level I WHO hypertension ] . - pubmed
Blood pressure tests were carried out on 40 shift workers with a hypertension level of 1 ( according to WHO ) . - pubmed
A patient with acquired intestinal malabsorption developed a motor - sensory polyneuropathy with a recurrent remittent course , normal CSF and reduced motor and sensory conduction velocities . - pubmed
A similar effect was noted in cells from patients with benign hyperplasia ( BPH ) . - pubmed
A controlled , parallel group study of the analgesic efficacy of flupirtine maleate , was compared against diclofenac sodium in 40 orthopaedic patients with post - operative pain . - pubmed
We compared red cell exchange transfusions ( RC Ex ) on the Aminco Celltrifuge ( continuous flow cell separator ) with conventional transfusions in 17 patients aged between 7 and 24 years who have transfusion dependent homozygous beta - thalassaemia and two other patients with chronic transfusion dependent anaemias aged 20 and 22 . - pubmed
[ Pharmacokinetics of benzylpenicillin and gentamycin administered by different routes to patients with acute and chronic nonspecific lung diseases ] . - pubmed
Pharmacokinetic studies showed that endobronchial administration of benzylpenicillin and gentamicin to patients with acute and chronic pneumonia unlike intramuscular administration provided the antibiotic concentrations in bronchial secretions effective against middle sensitive and moderately resistant strains of microorganisms within 1 - 5 hours . - pubmed
In this study , we report the use of extracorporeal membrane oxygenation ( ECMO ) to stabilize two patients with necrotizing tracheobronchitis . - pubmed
ECMO and bronchoscopy are effective forms of therapy for patients with life - threatening necrotizing tracheobronchitis when conventional modalities of treatment have failed . - pubmed
The authors describe the course of a severe asthma emergency in a boy aged 13 years . - pubmed
Analyzing data from two large controlled clinical trials in patients with chronic liver disease : 1 ) the multicenter trial of prednisone versus placebo in cirrhosis conducted by the Copenhagen Study group for Liver diseases ( CSL-1 ) and 2 ) the multinational trial of azathioprine versus placebo in primary biliary cirrhosis ( PBC-1 ) we have developed indices for prediction of prognosis and therapeutic effect using Cox 's multiple regression model for censored survival data . - pubmed
Several inanimate surfaces ( eg , plastic , wood , and steel ) and particulate fomites ( eg , wood shavings , hay , straw , and feces ) , common to the environment of confined small ruminants , were inoculated with Corynebacterium pseudotuberculosis in axenic purulent exudate that had been surgically removed from a naturally occurring case of caprine caseous lymphadenitis . - pubmed
A histochemical study of amines in palatal tissue from normal and glycosuric mice . - pubmed
Auto - immune myocarditis in rabbits immunized with rabbit heart . - pubmed
Synthesis of phospholipid in the blood of patients with essential hypertension . - pubmed
[ Immune reactions of rats with experimental induced hyperphenylalaninemia ] . - pubmed
Dietary fats and atherosclerosis in rat and rabbit . - pubmed
Eosinophilic myositis in cattle . - pubmed
[ Changes in the immunobiologic properties of Ehrlich ascites carcinoma under the effect of suspension from normal rat tissues . - pubmed
B lymphocyte studies , in vivo and in vitro , were performed in 28 patients with systemic lupus erythematosus ( SLE ) . - pubmed
Pemphigus - like antibodies in the horse and direct immunofluorescence testing in equine dermatophilosis . - pubmed
Indirect immunofluorescence testing for pemphigus - like antibodies was performed on 79 horses : 28 horses with various nonpemphigus dermatologic diseases , 21 horses with various nondermatologic diseases , and 30 normal horses . - pubmed
Pemphigus - like antibodies were detected in 6 horses : 3 normal horses with titers of 1:40 , 2 horses with dermatophilosis at titers of 1:10 and 1:80 , and 1 horse with lymphosarcoma at a titer of 1:320 . - pubmed
It was concluded that equine pemphigus - like antibodies are a potential source of misinterpretation and misdiagnosis in indirect immunofluorescence testing . - pubmed
It was concluded that equine dermatophilosis is a potential source of misinterpretation and misdiagnosis in direct immunofluorescence testing . - pubmed
Chick embryo fibroblast ( CEF)-grown stocks of the WSN strain of influenza A(HINI ) contain two variants which were designated F and C for fuzzy and clear plaque morphology on Madin - Darby bovine kidney ( MDBK ) cells . - pubmed
Amelioration of mesangial volume and surface alterations following islet transplantation in diabetic rats . - pubmed
This information is especially helpful in azotemic patients with hypertension . - pubmed
Culex ( Melanoconion ) taeniopus is a vector of Venezuelan encephalitis ( VE ) virus at a marsh focus in Guatemala and has low mesenteronal thresholds for infection by and transmission of two enzootic strains of VE virus . - pubmed
taeniopus to mesenteronal infection by this VE strain probably represents a key factor in the apparent disappearance of epizootic VE virus from the marsh focus following the 1969 outbreak . - pubmed
[ Ischemic cerebrovascular disease in patients with atrial fibrillation ] . - pubmed
The purpose of this retrospective study was to elucidate 1 ) which subgroups are prone to have ischemic cerebrovascular disease ( CVD ) among patients with atrial fibrillation ( Af ) , 2 ) vulnerable period of CVD after the diagnosis of chronic Af and 3 ) the clinical efficacy of antiplatelet therapy in chronic nonvalvular Af patients . - pubmed
During 9 years , a total of 479 patients included 124 cases with paroxysmal Af , 30 cases with paroxysmal Af initially which later changed to chronic Af and 325 cases with chronic Af were enrolled . - pubmed
This case provides support for the general concept of multidirectional differentiation in human epithelial cancers and in particular for the association of poor tumor differentiation with neuroendocrine expression in prostatic carcinoma . - pubmed
Effect of multiple denervations on the exercise hyperpnea in awake ponies . - pubmed
Third , in ponies with all three denervations together , the predominant response was an increase , not a decrease , in the exercise hyperventilation ; this increase was greater than that predicted from the individual lesions . - pubmed
Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality . - pubmed
Oscillations in cytoplasmic free calcium concentration in human pancreatic islets from subjects with normal and impaired glucose tolerance . - pubmed
Such oscillations were observed even in some islets from patients with impaired glucose tolerance . - pubmed
In one islet from a diabetic patient there was no response to glucose , whereas that islet displayed [ Ca2+]i - oscillations in response to tolbutamide , suggesting that sulphonylurea treatment can mimic the complex pattern of glucose - induced [ Ca2 +]i - oscillations . - pubmed
Interestingly , even subjects with impaired glucose tolerance had islets that responded with oscillations in [ Ca2 +]i upon glucose stimulation , although it is not known to what extent the response of these islets was representative of most islets in these patients . - pubmed
UNLABELLED : Radiofrequency current catheter ablation was attempted for 17 morphologies of ventricular tachycardia ( VT ) in 14 patients . - pubmed
Five patients had underlying heart disease . - pubmed
After ablation , 14 VTs ( 14/17 = 82 % ) of 11 patients ( 11/14 = 79 % ) could not be induced by electrical stimulation . - pubmed
In 4 patients , application of radiofrequency current was required 10 or more times because of a possible large arrhythmogenic area , or because of reinduction of VT , even though VT was terminated by radiofrequency current . - pubmed
No major complication was observed except for complete right bundle branch block in 1 patient . - pubmed
[ Polysomnographical studies of a patient with severe myoclonic epilepsy in infancy ] . - pubmed
In order to evaluate the brain function of a boy with severe myoclonic epilepsy , we performed serial polysomnographical studies . - pubmed
PBMC for patients with autoimmune diseases produce autoantibodies of the same specificities but at lower levels compared to the donor . - pubmed
SCID recipients of patients ' PBMC fail to develop clinical disease although some histological lesions suggestive of autoimmunity have been reported . - pubmed
Transfer of autoimmunity from rodents to SCID mice has been successful in some instances . - pubmed
Despite obstacles related to limited survival and varying degrees of graft vs host disease ( GVHD ) , SCID mice should prove to be a useful vehicle to explore autoantibody regulation . - pubmed
As a result , prognostic factors have been evaluated in an attempt to identify those patients with presumed early stage disease who will be at high risk for recurrence . - pubmed
RESULTS : When ER and PR and combined ER / PR status were analyzed separately , patients with receptor - positive lesions had significantly better disease - free survival than those with receptor - negative lesions . - pubmed
A 12 - year - old boy with a history of " migraine " headache presented with an increasingly severe headache accompanied by emesis and unsteadiness . - pubmed
Although rare in children , isolated angiitis of the central nervous system can occur in children and aggressive immunosuppression should be considered as the mode of therapy . - pubmed
Recruitment of T lymphocytes to lymph nodes in patients with HIV infection is critical to the pathogenesis of disease . - pubmed
25 rats with alimentary hypercholesterolemia induced by diet rich in cholesterol and mercazoline were exposed to frontomastoid impulse current ( 1000 Hz , 0.75 mA ) . - pubmed
A retrospective analysis of the MRI studies of 25 patients with pathologically proven pineal region tumours was performed , focused on the relationship between the tumour and neighbouring structures . - pubmed
In 10 of the 14 patients ( 71 % ) with germ cell tumours tectal compression was of the invasive type ; 8 patients ( 57 % ) had multiple tumours and in 13 ( 93 % ) the tumor margins were irregular . - pubmed
One - kidney , one clip ( 1K,1C ) and two kidney , one clip ( 2K,1C ) Goldblatt hypertensive rats were treated for 2 wk with bosentan ( 100 mg.kg-1.day-1 ) in their chow , and systolic blood pressure was measured by the tail - cuff method . - pubmed
Treatment with bosentan did not result in a significant change in systolic blood pressure or in the structure of small coronary , renal cortical , mesenteric , or femoral arteries in 1 K , 1C or in 2 K , 1C hypertensive rats . - pubmed
alpha - Conotoxin imperialis I inhibits nicotine - evoked hormone release and cell proliferation in human neuroendocrine carcinoma cells . - pubmed
[ Interrelations of the calcium concentration in breast milk with maternal intake of cow 's milk and milk products , bone resorption and bone mineral density during lactation ] . - pubmed
coli in large quantities and should prove useful as a standardized allergen for sensitive and specific immunodiagnosis of ABPA , especially in patients with central bronchiectasis . - pubmed
These sperm antigens are involved in binding to zona pellucida of the human oocyte . - pubmed
The recombinant human sperm NZ-2 antigen may find applications in the development of a contraceptive vaccine , and diagnosis and treatment of infertility in humans . - pubmed
A randomized multicenter trial is currently underway and is evaluating the long - term visual results documented in 609 patients with subfoveal CNV who underwent control and eventual PDT at 3 - month intervals . - pubmed
If PDT proves to be beneficial , an easy and non - invasive treatment modality could be offered to numerous patients who demonstrated occult classic CNV and are otherwise facing an extremely poor prognosis . - pubmed
ST tendons were harvested either with or without their distally attached tibial bone plugs from human cadavers and were folded to a three - stranded graft . - pubmed
In our experiments , cultured hepatocytes isolated from normal and hypothyroid adult rats were used . - pubmed
Therefore , the effect of tri - iodothyronine ( T3 ) was investigated using cultured hepatocytes from hypothyroid rats as an in vitro model . - pubmed
Cold - shock domain proteins in vertebrates contain a highly conserved domain which is related to the Escherichia coli cold - shock proteins . - pubmed
Here we report the cloning of a cold - shock domain protein from zebrafish embryo . - pubmed
Using the combination of PCR techniques with degenerate primers , 5'RACE and 3'RACE , the full length cDNA of a cold - shock domain protein in the zebrafish embryo was successfully cloned without constructing and screening a library . - pubmed
HIV recent advances in AIDS research : genetics , molecular biology and immunology . - pubmed
BACKGROUND : Tobacco smoking is the single most preventable cause of death in the United States today . - pubmed
STUDY DESIGN : Twenty - four women diagnosed as having gestational diabetes were compared to 22 nondiabetic , matched controls . - pubmed
Women with gestational diabetes had a significantly lower level than those with normal glucose tolerance . - pubmed
We undertook a randomized , crossover study to investigate the effects of 6 wk of treatment with regular terbutaline ( 1 mg four times a day ) , regular budesonide ( 400 microg twice a day ) , combined treatment , and placebo in subjects with mild to moderate asthma . - pubmed
Chloptosin ( 1 ) was found to induce apoptotic activity in apoptosis - resistant human pancreatic adenocarcinoma cell line AsPC-1 and showed a strong antimicrobial activity against Gram - positive bacteria including methicillin - resistant Staphylococcus aureus . - pubmed
The misdiagnosis of surgically treatable conditions in as many as 21 ( 13.5 % ) of the 156 patients calls for better neurological evaluation of patients admitted for stroke in tertiary and non - tertiary hospitals . - pubmed
New monitoring techniques as the measurement of systolic pressure variations or transoesophageal Doppler echocardiography will probably find a place in the management of trauma patients in the near future . - pubmed
CASE : A 29 - year - old woman presented with a serious vulvar hematoma caused by a straddle bicycle accident . - pubmed
The following variants were found in scrapie - affected goats : VV(21 ) , LL(23 ) , GG(49 , ) SS(49 ) , HH(143 ) , HR(143 ) , RR(154 ) , PP(168 ) , PP(240 ) , SP(240 ) and SS(240 ) . - pubmed
Allergic and photoallergic contact dermatitis to Olaquindox in a pig breeder with prolonged photosensitivity . - pubmed
This case report details the evaluation and treatment of a rapidly progressive and destructive subtalar lesion that occurred in a healthy 27 - year - old man after incidental trauma . - pubmed
This retrospective MRI analysis of a group of patients with polymicrogyria , without associated porencephaly or schizencephaly , was conducted to elucidate gross morphological findings of polymicrogyria in a clinical population . - pubmed
Seventy - one patients with polymicrogyria diagnosed by MRI were reviewed by two radiologists . - pubmed
The polymicrogyria was unilateral in 30 ( 42 % ) patients , bilateral in 41 ( 58 % ) patients . - pubmed
We describe a unique case , whereby a patient presenting with seizures and slight impairment of higher functions , underwent frontal lobectomy for a mass lesion . - pubmed
The patient remained well after 18 months of follow - up with no radiological progression of a known tumor residuum . - pubmed
Authors tested the efficacy of an in - home respite intervention to reduce peripheral markers of SAM activation and psychological distress in spousal caregivers of patients with Alzheimer disease . - pubmed
Activity of ascaridol from the anthelmintic herb Chenopodium anthelminticum L. against sensitive and multidrug - resistant tumor cells . - pubmed
Ascaridol is the active principle of the American wormseed Chenopodium anthelminticum L. We isolated ascaridol from a commercial preparation of Chenopodium oil and analyzed its activity against different tumor cell lines in vitro ( CCRF - CEM , HL60 , MDA - MB-231 ) . - pubmed
Rhizomelic chondrodysplasia punctata is a human autosomal recessive disorder characterized by skeletal , eye and brain abnormalities . - pubmed
The rats were randomized to four groups : intravenous valsartan ( 10 mg / kg , n = 8) , irbesartan ( 10 mg / kg , n = 8) , or saline vehicle ( controls , n = 14 ) over 30 minutes before reperfused myocardial infarction , and sham ( n = 8) . - pubmed
After washing and reacting with 4 - chloro-1 - naphthol and H2O2 , the appearance of purple spots indicated the presence of B. - pubmed
Blood pressure and renal clearances in hypertensive dogs following tissue injury . - pubmed
The following study improves the effectiveness of pelvic floor exercise in women with stress urinary incontinence . - pubmed
A group of 27 women with stress urinary incontinence performed specific pelvic floor exercises twice a week for 45 minutes under a therapist 's supervision for a period of 12 weeks . - pubmed
The urodynamic results showed that 48.2 % of the patients did not have urinary loss , however , 51,8 % of the patients that had a loss showed an increase in vesicle volume , and only 7.3 % remained unchanged . - pubmed
MATERIAL AND METHODS : One hundred and seven subjects with ( cases ) and 52 subjects without ( controls ) chronic arsenic poisoning were examined by spirometry . - pubmed
Multi - institutional randomized phase II trial of the epothilone B analog ixabepilone ( BMS-247550 ) with or without estramustine phosphate in patients with progressive castrate metastatic prostate cancer . - pubmed
PURPOSE : To evaluate the antitumor activity and safety of the epothilone B analog , ixabepilone , with or without estramustine phosphate ( EMP ) , in chemotherapy - naive patients with progressive castrate metastatic prostate cancer . - pubmed
Grades 3 and 4 toxicities experienced by more than 5 % of patients included neutropenia ( 22 % ) , fatigue ( 9 % ) , and neuropathy ( 13 % ) on the ixabepilone arm , and neutropenia ( 29 % ) , febrile neutropenia ( 9 % ) , fatigue ( 9 % ) , neuropathy ( 7 % ) , and thrombosis ( 6 % ) on the ixabepilone + EMP arm . - pubmed
CONCLUSION : Ixabepilone , with or without estramustine phosphate , is well tolerated and has antitumor activity in patients with castrate metastatic prostate cancer . - pubmed
Moreover , these Allium plants showed chemopreventive effects against human leukemia cells . - pubmed
We present a case of a 47 - year - old patient with arterial hypertension and progressive ST segment changes with a T wave inversion during 2 years of observation . - pubmed
During subsequent two last years the patient was repeatedly hospitalised due to chest pain . - pubmed
Important progress in the diagnosis of Chlamydia trachomatis ( C. - pubmed
CONCLUSION : Supplementary AVP infusion in patients with advanced vasodilatory shock and severe postoperative multiple organ dysfunction syndrome did not compromise cutaneous reactive hyperaemia and flowmotion when compared with norepinephrine infusion alone . - pubmed
We report about two patients with extramedullary plasmocytoma , one of them with an extremely rare triple manifestation in the upper airway . - pubmed
In patients with atherosclerosis , antiplatelet therapy is indicated and treatment of vascular risk factors should have high priority . - pubmed
METHODS : Ten patients with AR undergoing pollen SLIT with a weekly dose of 200,000 SQ - U , 10 with a weekly dose of 24,000 SQ - U of glycerinated mixture of Betula verrucosa , Corylus avellana and Alnus glutinosa and 10 with placebo were included in the study . - pubmed
CONCLUSIONS : Sublingual immunotherapy induced a dose - dependent systemic allergen - specific immunological response in children with AR . - pubmed
A 34 - year - old man was admitted with dyspnea and low grade fever . - pubmed
METHODS : Three separate conformal plans were generated for 37 patients with lung cancer : plan 1 corrected for heterogeneity , plan 2 did not correct for heterogeneity , and plan 3 used identical beams and monitor units from plan 2 but with heterogeneous calculations . - pubmed
In the present study , we examined differences in responses to chemotherapy in microvascular EC lines from tumoral ( T - EC ) and normal ( N - EC ) mouse liver tissues . - pubmed
CASE : We present the case of a 25 - year - old woman with appendiceal carcinoid tumor treated with intraperitoneal cisplatin for peritoneal recurrence after a fertility - sparing cytoreductive procedure . - pubmed
Fluid dynamics of gingiva in diabetic and systemically healthy periodontitis patients . - pubmed
The objectives of this study were ( i ) to investigate the alterations in the fluid dynamics of periodontium in diabetic periodontitis patients , and present the association of this phenomenon with the metabolic control of DM ; ( ii ) to reveal any correlation between the fluid dynamics of periodontium and clinical signs of periodontal disease in DM and periodontitis . - pubmed
DESIGN : Fifteen well - controlled diabetic chronic periodontitis patients ( Group 1 ) , 14 systemically healthy chronic periodontitis patients ( Group 2 ) , and 14 systemically and periodontally healthy individuals were included in the study . - pubmed
Apoptosis is a cause of the limbic system neuronal cells defect in patients suffering from depression . - pubmed
METHOD : The study comprised of 32 patients diagnosed with depression . - pubmed
METHODS : We conducted a randomized , double - blind , placebo - controlled , parallel - group study of BtA ( Dysport ) for leg spasticity in 64 children with cerebral palsy . - pubmed
Young children are at increased risk for hypoxaemia and hypercapnea during flexible laryngoscopy due to the small size and increased collapsibility of their airways . - pubmed
OBJECTIVE : The objective of this study was to detail the epidemiologic characteristics and natural history of HIV-1 natural viral suppressors ( NVSs ) , a cohort of HIV-1 - infected individuals who are able to suppress viral replication to undetectable levels in the absence of therapy . - pubmed
The incidence and prevalence of NVS were calculated by performing a chart review on all patients seen in 1 clinic in a 10 - year period . - pubmed
INTRODUCTION : To avoid the risk of complications of biliary drainage , a feasibility study was carried out to determine whether it might be possible to fast - track surgical treatment , with resection before biliary drainage , in jaundiced patients with proximal pancreatic / peri - ampullary malignancy . - pubmed
CONCLUSIONS : Fast - track management by resection without biliary drainage of selected patients with distal biliary strictures is safe and has the potential to reduce the waiting time to surgery , overall numbers of biliary drainage procedures and the complications thereof . - pubmed
Several randomized trials of catheter - directed thrombolysis versus operative revascularization in patients with acute lower extremity ischemia were performed in the mid-1990 s. Although the outcomes of these trials were not definitive , they did provide insight into potential uses and techniques of catheter - directed thrombolysis and lytic agents . - pubmed
Tumor tissue specimens from two patients with MPM were engrafted subcutaneously in SCID mice and blood samples were obtained and pooled every 2 weeks after xenotransplantation until 14 weeks when the mice were killed . - pubmed
No patients with lung cancer regardless of asbestos exposure exhibited positive antibody titer against the two antigens . - pubmed
RECENT FINDINGS : Vitamin D deficiency is common among both healthy and ill adolescents worldwide , even in sunny countries . - pubmed
SUMMARY : Further studies are needed to examine the implications of vitamin D deficiency among adolescents and the most appropriate treatment regimens to prevent this problem . - pubmed
There are sufficient data to support the importance of educating , preventing , and treating vitamin D deficiency in adolescents to improve their long - term health . - pubmed
The toxicities of these peptides to microbial and cancer cells were generally & lt;200 microM. - pubmed
[ Randomized control study of sequential non - invasive following short - term invasive mechanical ventilation in the treatment of acute respiratory distress syndrome as a result of existing pulmonary diseases in elderly patients ] . - pubmed
OBJECTIVE : To evaluate the feasibility and the efficacy of sequential non - invasive mechanical ventilation ( MV ) following short - term invasive MV in the treatment of acute respiratory distress syndrome ( ARDS ) consequent to pulmonary diseases in the elderly patients . - pubmed
METHODS : Thirty - two elderly patients of ARDS were enrolled and grouped into two groups ( sequential therapy group and control group ) randomly ( 16 cases in each group ) . - pubmed
CONCLUDING REMARKS : Patients on antipsychotic drugs should undergo regular testing of blood sugar , lipid profile , as well as body weight , waist circumference and blood pressure , with recommended time intervals between measures . - pubmed
METHODS : The role of 17beta - estradiol , medroxyprogesterone acetate ( MPA ) , and drospirenone during renal injury was studied in Wistar rats subjected to uni - nephrectomy plus aldosterone salt treatment . - pubmed
RESULTS : Aldo - salt treatment of intact , ovariectomized , and estradiol - treated female rats resulted in remnant kidney hypertrophy without structural damage . - pubmed
Losartan therapy in adults with Marfan syndrome : study protocol of the multi - center randomized controlled COMPARE trial . - pubmed
Aortic disease , leading to progressive aneurysmal dilatation and dissection is the main cause of morbidity and mortality of Marfan patients . - pubmed
beta blockers and elective surgery ) does postpone but can not prevent aortic complications in these patients . - pubmed
The main objective of this trial is to assess whether losartan treatment leads to a clinically relevant decrease of aortic dilatation in adult patients with Marfan syndrome . - pubmed
We will enroll 330 patients with MFS who will be randomly assigned to receive losartan or not . - pubmed
DISCUSSION : The COMPARE study will provide important evidence of effects of losartan treatment in adult Marfan patient population . - pubmed
The management of patients with aneurysmal subarachnoid hemorrhage ( SAH ) requires a fundamental knowledge of the disease , its therapeutic options and possible complications . - pubmed
This article provides an overview about the pre- , peri- and postoperative management of patients with SAH . - pubmed
Functional magnetic resonance imaging ( fMRI ) data were recorded in 23 participants with PTSD ( 13 women , 10 men ) , 21 trauma - exposed controls ( 9 women , 12 men ) , and 42 non - trauma - exposed controls ( 22 women , 20 men ) while they viewed masked facial expressions of fear . - pubmed
METHODS : All patients admitted to Christchurch Public Hospital with AP between July 2005 and December 2008 were identified from a prospectively collected database . - pubmed
Patients with biliary AP had significantly higher median ( range ) ALT than those with non - biliary causes ( 200 units / l [ 63 - 421 units / l ] vs. 33 units / l [ 18 - 84 units / l ] ; P & lt ; 0.001 ) . - pubmed
Special attention should be paid to patients with pseudoexfoliation . - pubmed
Exploring new applications for Rhodiola rosea : can we improve the quality of life of patients with short - term hypothyroidism induced by hormone withdrawal ? - pubmed
The latter option is simpler but induces a profound state of hypothyroidism , which results in physical and mental complaints that may interfere severely with the patient 's activities of daily living . - pubmed
Rhodiola rosea is a popular plant in traditional medical systems in Eastern Europe and Asia with a reputation for stimulating the nervous system , decreasing depression , enhancing work performance , and eliminating fatigue , all features of clinical hypothyroidism . - pubmed
rosea as a viable alternative treatment for the symptoms of short - term hypothyroidism in patients with DTC who require hormone withdrawal . - pubmed
This study aimed to investigate the differential effect and mechanism of tumor microenvironments , cycling hypoxia and non - interrupted hypoxia , on tumor cell radiosensitivity in the human U87 glioblastoma tumor model . - pubmed
We exposed U87 cells and mice bearing U87 glioma to experimentally imposed cycling or non - interrupted hypoxic stress in vitro and in vivo prior to treatment with ionizing irradiation . - pubmed
Furthermore , we compared the omega-3 index in 14 OHCA - patients suffering their first MI with that of 185 first - time MI - patients without SCA ; mean values being 4.59 % and 6.48 % , respectively ( p = 0.002 ) . - pubmed
METHODS : Between 1/1988 and 2/2001 , 111 consecutive pulmonary resections were conducted in patients with bronchial carcinoids . - pubmed
RESULTS : 97 patients with typical and 14 with atypical carcinoids were identified . - pubmed
The preoperative diagnosis of typical or atypical carcinoid had been correct in 56 patients ( 50.5 % ) . - pubmed
In patients with typical and atypical carcinoids , the 5 - year survival rates were 94 % and 82 % , respectively ( n.s . ) - pubmed
CONCLUSIONS : Patients with bronchial carcinoids who underwent a radical oncological resection with mediastinal lymphadenectomy have very good survival chances . - pubmed
METHODS : A nonrandomized , retrospective chart review was performed on pediatric patients ( younger than 18 years of age ) treated with a 360 - degree suture trabeculotomy for glaucoma . - pubmed
CONCLUSIONS : Children with a range of ocular pathologies can be successfully treated with 360 - degree suture trabeculotomy . - pubmed
Natural orifice translumenal endoscopic surgery inguinal hernia repair : a survival canine model . - pubmed
RESULTS : All animals thrived postoperatively and did not manifest signs of peritonitis or sepsis at any point . - pubmed
A 31/2 - year - old apparently healthy girl with normal development presented with steatorrhoea . - pubmed
BACKGROUND : Patients with chromosome 5 abnormalities and high - risk myelodysplastic syndromes or acute myeloid leukemia have a poor outcome . - pubmed
We hypothesized that increasing doses of lenalidomide may benefit this group of patients by inhibiting the tumor clone , as assessed by fluorescence in situ hybridization for del(5q31 ) . - pubmed
Using the International Working Group criteria for acute myeloid leukemia and myelodysplastic syndrome the overall response rate in treated patients with acute myeloid leukemia was 20 % ( 3/15 ) , while that for patients with myelodysplastic syndrome was 36 % ( 4/11 ) . - pubmed
CONCLUSIONS : Our data support a role for higher doses of lenalidomide in poor prognosis patients with myelodysplastic syndrome and acute myeloid leukemia with deletion 5q . - pubmed
Although SP cells isolated from some adult tissues have been reported elsewhere , isolation and characterization of human trophoblast SP remained to be reported . - pubmed
Their low toxicity towards mice fibroblasts at maximal concentrations , their antioxidant activity , comparable or even higher than that of ascorbic acid as determined by direct quenching of the DPPH radical , and their potential for significantly altering total and LDL cholesterol levels , suggest that these conjugates merit further studies in the treatment of cardiovascular or other related diseases . - pubmed
Eight patients were admitted for severe , refractory gastrointestinal bleeding , seven of whom were actively bleeding . - pubmed
Causes of bleeding were gastric varices secondary to portal hypertension ( n = 3 ) ; gastroduodenal artery aneurysm or fundal aneurysmal arterial malformation ( n = 3 ) ; and Dieulafoy 's ulcer ( n = 2 ) ; the latter five patients having arterial bleeding . - pubmed
Metrics of cellular and vascular infiltration of human acellular dermal matrix in ventral hernia repairs . - pubmed
BACKGROUND : Human acellular dermal matrix is used for ventral hernia repair , as it resists infection and remodels by means of surrounding tissue . - pubmed
METHODS : Fifty - six guinea pigs underwent inlay human acellular dermal matrix ventral hernia repair with the basement membrane oriented toward or away from the peritoneum . - pubmed
CONCLUSIONS : Cellular and vascular infiltration into human acellular dermal matrix for ventral hernia repairs was greater from musculofascia than from subcutaneous fat , and the basement membrane inhibited cellular and vascular infiltration . - pubmed
Chronic amitriptyline overdose in a child . - pubmed
We describe a case of a 6 - year - old girl who was prescribed amitriptyline 30 mg nightly for sleep problems , but was mistakenly given 300 mg ( 15 mg / kg ) nightly for over a month . - pubmed
She presented to the local children 's hospital in status epilepticus with significant cardiac conduction abnormalities on ECG . - pubmed
In this report , we describe a 60 - year - old woman with chronic kidney disease whose kidney biopsy showed FSGS . - pubmed
METHODS : The antiproliferative effect of erufosine in vitro was determined by the MTT dye reduction assay , and the antineoplastic efficacy on tumor growth was investigated by relating the mean total tumor volumes of treated and control rats . - pubmed
Moreover , administration of erufosine to rats bearing autochthonous methylnitrosourea - induced rat mammary carcinomas caused a significant dose - related tumor remission by more than 85 % ( p & lt ; 0.05 ) , which was well tolerated , as evidenced by a body weight loss of maximally 7 % and reduced tumor - related mortality ( 2 of 35 instead of 6 of 18 controls , p & lt ; 0.002 ) . - pubmed
CONCLUSIONS : The results clearly indicate that erufosine possesses high antineoplastic activity not only in human breast cancer cell lines in vitro but also in rat mammary carcinoma in vivo . - pubmed
To determine if characteristics of the microbiome are associated with these phenotypes we used a phylogenetic microarray to compare small intestine bacterial communities of wild type and congenic CF mice . - pubmed
CF mice exhibited significant enrichment of Mycobacteria species and Bacteroides fragilis , previously associated with GI infection and immunomodulation . - pubmed
Antibiotic administration to WT and CF animals resulted in convergence of their microbiome composition and significant increases in community diversity in CF mice . - pubmed
The ability of this approach to finely tune the structural characteristics of chitosan nanocapsules enabled us to systematically investigate the influence of capsule size , wall thickness , and porosity on their efficiency as drug delivery vehicles against mouse mastocytoma cells after loading them with curcumin , a natural lipophilic anticancer drug . - pubmed
BACKGROUND : Muller 's muscle - conjunctival resection is used to correct mild to moderate ptosis commonly encountered in the rejuvenation patient population . - pubmed
METHODS : Patients who underwent ptosis correction using Muller 's muscle - conjunctival resection with greater than 10 - month follow - up were included . - pubmed
On patients with asymmetric ptosis , it significantly improved eyelid symmetry to within 1.0 mm from 85 percent of patients before surgery to 95 percent after surgery , and to within 0.5 mm from 53 percent before surgery to 75 percent of patients after surgery ( p = 0.036 ) . - pubmed
Furthermore , the mean correction of ptosis was not significantly different between medium- ( 1.58 + - 0.93 mm ) and long - term ( 1.32 + - 0.93 mm ) follow - up patients ( p = 0.258 ) . - pubmed
( -)- Epigallocatechin-3 - gallate ( EGCG ) , the principal constituent of green tea , protects neurons from toxic insults by suppressing the microglial secretion of neurotoxic inflammatory mediators . - pubmed
Central nervous system ( CNS ) diseases are most widely investigated diseases among all others in respect to the ginseng 's therapeutic effects . - pubmed
In this review , we tried to provide comprehensive information on the pharmacological and therapeutic effects of ginseng and ginsenosides on neurodegenerative and other neurological diseases . - pubmed
Side by side comparison of the therapeutic effects in various neurological disorders may widen our understanding of the therapeutic potential of ginseng in CNS diseases and the possibility to develop not only symptomatic drugs but also disease modifying reagents based on ginseng . - pubmed
Age - related hearing loss patterns in Fischer 344 / NHsd rats with cisplatin - induced hearing loss . - pubmed
These trials enrolled 1748 periodontitis patients . - pubmed
Seven trials enrolled periodontitis patients that were otherwise healthy , 18 trials recruited periodontal patients with various co - morbidities , such as CVD or diabetes . - pubmed
They were randomly classified in two group of patient - controlled intravenous analgesia for postoperative pain control , one was group S [ ( sufentanil ) ( n = 30 ) ] and the other was group S + M [ ( magnesium sulphate / sufentanil ) ( n = 30 ) ] . - pubmed
CONCLUSIONS : This study showed that magnesium sulphate added to sufentanil through PCIA is an effective method to alleviate pain in patients undergoing lower limb orthopedic surgery . - pubmed
Moreover , we found fewer side effects on magnesium - sufentanil regimen in terms of in nausea , vomiting , and sedation ; and patients ' satisfaction in this regimen was more rather than that in the regiment of sufentanil alone . - pubmed
sylvestris extract and compounds 1 , 6 - 8 and 9 were evaluated for antitumor activities against HepG2 ( human hepatocellular carcinoma ) , MG-63 ( human osteosarcoma cells ) , B16 ( melanoma cells ) and HeLa ( human cervical carcinoma cells ) lines by the MTT method . - pubmed
A patient with a congenital mucocele diagnosed by prenatal ultrasound screening showing a cystic lesion of the tongue is presented herein . - pubmed
METHODS : Patient characteristics , clinical parameters and laboratory data were retrospectively analysed in patients with HSP with or without nephritis . - pubmed
RESULTS : A total of 535 patients with HSP were included in the study . - pubmed
HSP nephritis occurred in 267 patients ( 49.9 % ) , ranging from isolated haematuria in 5.2 % , mild proteinuria in 77.5 % , moderate proteinuria in 6.4 % and severe proteinuria in 10.9 % of cases . - pubmed
The intake of the mainly plant - derived n-3 PUFA alpha - linolenic acid ( ALA ) has been reported to be associated with a lower risk of CHD . - pubmed
After 3 years number of patients with AH did not significantly increase , but the structure of the disease changed : number of patients with stage 2 AH increased and of those with stage 1 AH decreased . - pubmed
METHODS : EAE was modeled in mice and the number of regulatory T cells ( Tregs ) in spleen of EAE mice was detected by flow cytometry . - pubmed
We wanted to characterize echocardiographic LV dysfunction in obese T2DM subjects as compared to non - diabetic obese controls . - pubmed
METHODS : One hundred patients with T2DM without clinical signs of heart failure ( 29 % females , mean + - SD age 58.4 + - 10.5 years , body mass index ( BMI ) 30.1 + - 5.5 kg / m(2 ) , blood pressure ( BP ) 141 + - 18/83 + - 9 mmHg ) and 100 non - diabetic controls ( 29 % females ) matched for age ( 58.6 + - 10.5 years ) , BMI ( 29.8 + - 4.0 kg / m(2 ) and systolic BP ( 140 + - 14 mmHg ) underwent echocardiography and color tissue Doppler imaging ( TDI ) . - pubmed
RESULTS : T2DM patients had more concentric hypertrophy with a relative wall thickness of 0.42 + - 0.07 vs controls 0.38 + - 0.07 , P & lt ; 0.001 . - pubmed
The need for a precise diagnostic algorithm is underlined by the awareness that both ALL therapy and related success rates may vary greatly between ALL subsets , from standard chemotherapy in patients with standard - risk ALL , to allotransplantation ( SCT ) and targeted therapy in high - risk patients and cases expressing suitable biological targets , respectively . - pubmed
Radiotherapy is a mainstay for treatment of many human cancer types , including head and neck squamous cell carcinoma ( HNSCC ) . - pubmed
METHODS : Retrospective analysis of patients with PSP / CBD admitted to an inpatient specialized palliative care service . - pubmed
RESULTS : In 38 patients , there were 63 admissions for swallowing difficulties , falls , pain , impaired communication , cognitive / mood disturbances , respiratory symptoms , and infection . - pubmed
We present a case of carcinoma of breast in a 50 - year - old woman , metastasising to mandibular ramus , condyle and surrounding soft tissue structure presenting as osteomylitis of condyle . - pubmed
Mycobacterium tuberculosis , the causative agent of tuberculosis , remains a leading cause of human morbidity and mortality worldwide , with approximately 8.6 million cases and 1.3 million deaths in 2012 . - pubmed
Cardiac MR enables diagnosis in 90 % of patients with acute chest pain , elevated biomarkers and unobstructed coronary arteries . - pubmed
OBJECTIVE : To assess the diagnostic value of cardiac MRI ( CMR ) in patients with acute chest pain , elevated cardiac enzymes and a negative coronary angiogram . - pubmed
METHODS : This study included a total of 125 patients treated in the chest pain unit during a 39 - month period . - pubmed
CMR delivered a correct final diagnosis in 90 % of patients with acute chest pain , elevated cardiac enzymes and a negative coronary angiogram . - pubmed
ADVANCES IN KNOWLEDGE : Diagnosing patients with acute coronary syndrome but unobstructed coronary arteries remains a challenge for cardiologists . - pubmed
Here we show that in budding yeast Saccharomyces cerevisiae telomere recombination elicits genome instability and accelerates cellular aging . - pubmed
To do this , a rat model of DM was established by streptozotocin injection followed by engraftment of autologous jugular veins to carotid arteries to induce intimal hyperplasia . - pubmed
Quantitative analysis of high - resolution microendoscopic images for diagnosis of neoplasia in patients with Barrett ' s esophagus . - pubmed
BACKGROUND AND AIMS : Previous studies show that microendoscopic images can be interpreted visually to identify the presence of neoplasia in patients with Barrett ' s esophagus ( BE ) , but this approach is subjective and requires clinical expertise . - pubmed
This study describes an approach for quantitative image analysis of microendoscopic images to identify neoplastic lesions in patients with BE . - pubmed
Primary wound healing was achieved in all patients . - pubmed
Overall SSTI recurrence rate was 28.0 % ( 95 % CI [ 21.6%-34.4 % ] ) and associated with contact with someone infected with methicillin resistant S. - pubmed
METHODS : A total of 207 women with PCOS and 192 controls were recruited . - pubmed
[ Evaluation of efficacy and safety of pelvic arterial embolization in women with primary postpartum hemorrhage ] . - pubmed
OBJECTIVE : To evaluate the efficacy and safety of pelvic arterial embolization ( PAE ) in women with intractable primary postpartum hemorrhage ( PPH ) . - pubmed
METHODS : Clinical data of 36 cases were analyzed retrospectively in which women underwent PAE for intractable primary PPH in Peking Union Medical College Hospital between Jan 2006 and Jan 2015 . - pubmed
CONCLUSION : PAE is a safe and effective treatment for intractable primary PPH which can prevent hysterectomy and preserve fertility of patients . - pubmed
In this review , we provide a perspective and summary of recent advances in the use of letrozole for breast cancer in Chinese patients . - pubmed
CONCLUSIONS : The rate of incidentally detected adenocarcinoma prostate in patients undergoing TURP for clinically diagnosed BPH was found to be only 5.2 % in our study which is low when compared with similar studies done elsewhere . - pubmed
Dyscalculia , like dyslexia , affects some 5 % of school - age children but has received much less investigative attention . - pubmed
Role of mir-15a/16 - 1 in early B cell development in a mouse model of chronic lymphocytic leukemia . - pubmed
In both human chronic lymphocytic leukemia ( CLL ) and the New Zealand Black ( NZB ) murine model of CLL , decreased levels of microRNAs miR-15a/16 play an important role in the disease . - pubmed
Furthermore , induced pluripotent stem ( iPS ) cells derived for the first time from NZB mice , provided insights into the B cell differentiation roadblock inherent in this strain . - pubmed
The effect of long - term amiodarone administration on myocardial fibrosis and evolution of left ventricular remodeling in a porcine model of ischemic cardiomyopathy . - pubmed
Amiodarone is effective in suppressing arrhythmias in heart failure patients . - pubmed
We investigated the effect of long - term amiodarone administration on myocardial fibrosis and left ventricular ( LV ) remodeling in a porcine model of ischemic cardiomyopathy . - pubmed
Eighteen infarcted farm pigs were randomized to receive long - term amiodarone administration for 3 months ( n = 9 ) or conventional follow - up ( n = 9 ) . - pubmed
This favorable safety profile suggests that long - term anti - arrhythmic therapy with amiodarone warrants further clinical investigation in the subpopulation of heart failure patients with significantly increased burden of arrhythmias . - pubmed
METHODS : Subjects were 123 patients with rectal cancer undergoing laparoscopic or open total mesorectal excision surgery with preventive ileostomy from 2012 to 2015 . - pubmed
Abiraterone acetate and prednisone in chemotherapy - naive prostate cancer patients : rationale , evidence and clinical utility . - pubmed
In a phase III trial of men with asymptomatic or minimally symptomatic , chemotherapy - naive mCRPC , treatment with oral abiraterone acetate plus prednisone led to a statistically significant improvement in the co - primary endpoints of overall survival and radiographic progression - free survival when compared with placebo plus prednisone . - pubmed
Ongoing trials are evaluating the role of abiraterone acetate plus prednisone in patients with nonmetastatic CRPC and metastatic hormone - sensitive prostate cancer , while further trials in the mCRPC setting are evaluating its use in combination regimens . - pubmed
Surgery is usually considered for patients who have a large goitre , compressive symptoms or significant ophthalmopathy . - pubmed
Central retinal artery occlusion in a 30 - year - old woman taking tranexamic acid . - pubmed
We present a case of a 30 - year - old woman who suffered a central retinal artery occlusion while taking tranexamic acid . - pubmed
Particularly , the occupancy of g_Pseudomonas , g_Sphingomonas , g_Agrobacterium , g_Achromobacter , and g_Roseateles decreased in ASD , whereas g_Streptococcus , g_Akkermansia , g_Rhodococcus , and g_Halomonas increased . - pubmed
We report a case of siliconoma with extensive involvement of multiple lymph nodes mimicking malignant features to emphasize that clinicians should carefully evaluate each patient 's medical history and disease status during differential diagnosis . - pubmed
The present study utilized the rat model of mild andropause to thoroughly evaluate the effects of G and soy extract on the adrenal gland and related blood hormones . - pubmed
METHODS : Single center , observational , prospective registry of consecutive patients with AF , undergoing clinical / echocardiographic evaluation in a University Hospital , as either in - patients or out - patients . - pubmed
CONCLUSIONS : Risk scores currently adopted for decision making on starting oral anticoagulation provide good prediction of long - term survival in unselected AF patients , especially in the outpatient setting . - pubmed
Accordingly , we present a case wherein a patient with documented eosinophilia and heart failure at the age of three - and - a - half years presented with endomyocardial fibrosis at the age of nine years . - pubmed
OBJECTIVE : The objectives of this retrospective analysis were to 1 ) report the prevalence of increased muscle tone in a convenience sample of 128 chronic stroke survivors with moderate / severe motor deficits and 2 ) quantify the relation between tone and motor impairment in chronic stroke survivors . - pubmed
The collective human effort to understand the brain and its common disease , stroke , has spanned many centuries , cultures , and societies . - pubmed
Is echocardiographic epicardial fat thickness increased in patients with coronary artery disease ? - pubmed
Results : This meta - analysis was performed on 13 studies involving 2,436 patients ( 1,622 with CAD , and 814 without CAD ) . - pubmed
The patients with CAD had a significantly higher echocardiographic EFT than those without CAD ( SMD=1.03 , 95 % CI= 0.70 - 1.37 , p=0.000 ) . - pubmed
More importantly , in a mouse model of acute myocardial infarction , the in vivo results of cardiac function , heart morphometry , and immunohistochemistry assessment all confirmed effective heart repair by the PTBC system . - pubmed
CONTEXT : Patients with hypoparathyroidism are treated with vitamin D and calcium . - pubmed
OBJECTIVE : We assessed the efficacy and safety of alfacalcidol in a large cohort of patients with idiopathic hypoparathyroidism ( IH ) and identified a subset who could be treated without oral calcium . - pubmed
SUBJECTS AND METHODS : We assessed 92 patients with IH who were receiving alfacalcidol and oral calcium to maintain an optimal serum total calcium level of 8.0 to 8.5 mg / dL during routine follow - up . - pubmed
Serum phosphorus levels normalized when the serum calcium level increased to 9.9 mg / dL , but this level of serum total calcium was associated with hypercalciuria in 90 % of patients . - pubmed
However , optimal calcium control was associated with hyperphosphatemia and hypercalciuria in most patients . - pubmed
Perennial canker diseases constitute major threats to the cherry industry productivity by reducing tree health , longevity , and yields . - pubmed
Materials and Methods : The data of 137 patients with at least one thyroid nodule & gt;=2 cm who underwent RFA combined with hydrodissection at our medical center from November 2014 to October 2016 were analyzed . - pubmed
Only one patient ( 0.7 % ) experienced laryngeal nerve injury after operation . - pubmed
UPLC - QTOF / MS - based metabolomics analysis of plasma reveals an effect of Xue - Fu - Zhu - Yu capsules on blood - stasis syndrome in CHD rats . - pubmed
RESULTS : SPECT showed reversible ischemia in 36 ( 59 % ) of these 61 patients , and converted to negative in 29 of them . - pubmed
monocytogenes but not with other Listeria species or Streptococcus groups A through G. The listeriolysin O latex agglutination assay ( LLOLAT ) was applied to 24 - h and 48 - h USDA primary enrichment cultures of 208 food samples obtained from refrigerators of listeriosis patients enrolled in a study to determine the role of foods in sporadic listeriosis . - pubmed
A 56 - year - old man who had twice previously undergone orthotopic heart transplantation was admitted with dyspnea and heart failure symptoms . - pubmed
Several months later , the patient was readmitted with worsening chest pain and dyspnea . - pubmed
We sought to analyze the long - term outcomes of OPCAB versus on - pump coronary artery bypass ( ONCAB ) in patients with moderate renal failure . - pubmed
CONCLUSIONS : OPCAB is associated with improved in - hospital renal outcomes , but is not associated with changes in short- or long - term mortality , or with the long - term cumulative incidence of end - stage renal failure requiring permanent dialysis in patients with moderate renal failure . - pubmed
Babesia gibsoni is one of the important pathogens causing severe incurable canine babesiosis , suggesting the necessity to develop a sensitive , specific , and highly automated diagnostic method for clinical application . - pubmed
RESULTS : The study population included 2382 PCa patients ( mean age 75 years ) . - pubmed
At initial GnRHa administration , 70 % of patients neither had lymph node nor distant metastases . - pubmed
Extreme responses to immune checkpoint blockade following bipolar androgen therapy and enzalutamide in patients with metastatic castration resistant prostate cancer . - pubmed
BACKGROUND : Immune checkpoint inhibition has been shown to have limited efficacy in patients with metastatic prostate cancer . - pubmed
CONCLUSIONS : These cases of mCRPC suggest that immune checkpoint blockade may have therapeutic potential in patients with prostate cancer , especially following immune activation ( " priming " ) using BAT and enzalutamide . - pubmed
Cerebral Microbleeds and Chronic Kidney Disease in Acute Ischemic Stroke Patients with Atrial Fibrillation . - pubmed
BACKGROUND : Cerebral microbleeds ( CMBs ) are associated with the risk of intracerebral hemorrhage in stroke patients with atrial fibrillation ( AF ) . - pubmed
We investigated the association between CMBs and chronic kidney disease ( CKD ) in patients with acute ischemic stroke and AF . - pubmed
RESULTS : Of the 357 included patients , 105 ( 29.4 % ) had CMBs . - pubmed
CKD ( eGFR & lt ; 60 mL / min/1.73 m2 ) was found in 131 ( 36.7 % ) patients . - pubmed
Patients with CKD showed a higher prevalence of any form of CMB ( 41.2 % versus 22.6 % , P & lt ; .001 ) , deep or infratentorial CMBs ( 19.9 % versus 9.3 % , P & lt ; .01 ) , and mixed CMBs ( 14.5 % versus 5.3 % , P & lt ; .01 ) than those without CKD . - pubmed
CONCLUSIONS : CMBs and CKD are common in acute ischemic stroke patients with AF , and CKD may be a risk factor for CMBs . - pubmed
BACKGROUND : Previous studies have been conducted to identify characteristics of patients with heart failure with preserved ejection fraction ( HFpEF ) , but the risk factors of HFpEF remain unclear . - pubmed
We investigated the associations between arterial stiffness and the risk of hospitalization for HFpEF patients . - pubmed
METHODS : For the case group , we enrolled patients with preserved EF who had been hospitalized for HF from April 2013 to March 2015 and examined the cardio - ankle vascular index ( CAVI ) . - pubmed
CONCLUSIONS : The present study has demonstrated that the high value of CAVI was independently associated with the hospitalization of HFpEF patients . - pubmed
While tolypodiol previously showed anti - inflammatory activity in a mouse ear edema assay , only 2 reduced in vitro thromboxane B2 and superoxide anion ( O2- ) generation from Escherichia coli lipopolysaccharide - activated rat neonatal microglia to any appreciable degree . - pubmed
Results : The screening results against various Gram - positive and Gram - negative bacterial strains revealed that N -( 2,3 - dihydro-1,4 - benzodioxin-6 - yl )- 4 - methylbenzenesulfonamide ( 3 ) , N -( 2 - bromoethyl )- N -( 2,3 - dihydro-1,4 - benzodioxin-6 - yl )- 4 - methylbenzenesulfonamide ( 5a ) and N -( 2 - phenethyl )- N -( 2,3 - dihydro-1,4 - benzodioxin-6 - yl )- 4 - methylbenzenesulfonamide ( 5b ) showed good inhibitory activity as compared to standard Ciprofloxacin . - pubmed
Several vaccine candidates have been introduced for immunization against Pseudomonas aeruginosa strains . - pubmed
Due to the rapid increase in several drug - resistant strains , P. - pubmed
Aedes species are common vectors for the clinically important alphaviruses - Chikungunya , Sindbis , and Ross River ( RRV ) viruses - with Aedes aegypti also being a vector for the flaviviruses dengue , Yellow Fever , and Zika viruses . - pubmed
aegypti was putatively implicated in the large 1979 - 1980 South Pacific Islands outbreak of RRV - the leading cause of arboviral disease in Australia today . - pubmed
A significant decrease in total HO volume in the rat blast injury model was observed by microCT imaging with no systemic complications following NG-25 therapy . - pubmed
Single cell RNA - sequencing of murine cells harvested from the injury site in a burn tenotomy injury model showed increased expression of these genes in MPCs during stages of chondrogenic differentiation . - pubmed
Comparative study of alterations in phospholipid profiles upon liver cancer in humans and mice . - pubmed
Comparative studies of molecular alterations upon cancer between mice and humans are of great importance in order to determine the relevance of research involving mouse cancer models to the development of diagnostic and therapeutic approaches in clinical practice as well as for the mechanistic studies of pathology in humans . - pubmed
Out of the 27 common differential signals , six types of phospholipids were also identified to undergo significant alterations in human serum upon liver cancer , including PC(34:2 ) , PC(36:4 ) , PC(38:6 ) , PC(36:2 ) , PC(38:4 ) and PC(42:9 ) . - pubmed
Statistical analysis of the relative intensity distribution of these six identified phospholipids in serum allowed confident determination of liver cancer in humans ( sensitivity 91.0 % , specificity 88.0 % , and accuracy 90.0 % ) . - pubmed
The purified acarbose was used to evaluate the hypoglycemia in streptozotocin ( STZ)-induced diabetic mice model . - pubmed
Therefore , acarbose from Actinoplanes hulinensis 1094 could be potentially used to make products for the treatment of type II diabetes . - pubmed
Cell populations of normal and tumor animals were divided into two groups with equal content of DNA to measure RNA content in either of them . - pubmed
[ Comparative assessment of metronidazole and fasygin in the treatment of vaginal trichomoniasis in girls ] . - pubmed
Xerophthalmia , or dry eye , is an old human affliction . - pubmed
However , tetracaine provided a motor block in a significantly greater number of patients than did pubivacaine ( 100 versus 42 % , rho less than 0.001 ) when both drugs were used at the 9.75 - mg dose level . - pubmed
Seven patients with reversible obstructive airways disease , who were unsatisfactorily relieved by conventional bronchodilating drugs , were admitted to a 1 - year - long therapeutic trial with beclomethasone dipropionate aerosol , 400 mug a day . - pubmed
With the intention to develop a new concept of venous ultrastructure in penile venous insufficiency , we studied the histopathology of 13 dorsal penile veins obtained from important patients during venous ligation because of proven venous leakage . - pubmed
To assess the role of altered renal and systemic production of thromboxane A2 and prostacyclin in the hepatorenal syndrome , urinary excretion of their major renal and extrarenal metabolites was measured in patients with compensated and decompensated liver disease , chronic renal failure , and hepatorenal syndrome . - pubmed
Urinary excretion rates of all prostanoids ( renal and extrarenal ) were increased in subjects with liver disease compared with normal controls . - pubmed
Moreover , they were considerably higher in subjects with severe hepatic decompensation but good renal function compared with those with hepatorenal syndrome . - pubmed
In contrast , the excretion rate of all metabolites was reduced in patients with chronic renal failure . - pubmed
When corrected for creatinine clearance , there was a strong correlation between prostanoid excretion and serum bilirubin in subjects with liver disease ; there was no difference , however , in the excretion of renal and extrarenal prostanoids between hepatorenal syndrome and severe hepatic decompensation . - pubmed
Detection of Borrelia burgdorferi in cerebrospinal fluid of patients with Lyme borreliosis . - pubmed
Experiments were undertaken to assess whether pretreatment of rats with the new calcium antagonist anipamil ( 5 mg / kg body weight , twice daily for 5 days ) protects the isolated heart against a submaximal calcium paradox . - pubmed
Conservative surgical treatment in infertile patients with endometriosis . - pubmed
Conditions of chronic use of sunscreens in human skin , however , are not established but it is possible that , under some circumstances , sunscreen use could enhance skin cancer risk . - pubmed
A programme to reduce the risk of infection by Echinococcus multilocularis : the use of praziquantel to control the cestode in a village in the hyperendemic region of Alaska . - pubmed
This paper reports the results of a 10 - year field trial designed to reduce the risk of infection by Echinococcus multilocularis to residents of a village in a hyperendemic area ( Savoonga , St. Lawrence Island ) . - pubmed
Northern voles , Microtus oeconomus , present in the village as commensals , served as an index of risk , as the incidence of infection in the voles provides information about the availability of eggs within the confines of the inhabited area . - pubmed
Two patients with the uncommon finding of involutional entropion of the upper lid were treated with surgery based on the principles used to treat common lower lid entropion . - pubmed
Monoclonal antibodies to human colorectal epithelium : markers for differentiation and tumour characterization . - pubmed
A panel of monoclonal antibodies ( MAbs ) has been obtained , directed against determinants of normal human colorectal epithelium . - pubmed
After subplantar administration of the antibiotics pad edema in albino rats was observed . - pubmed
Squamous cell carcinomas in the oral cavity and the oropharynx were diagnosed in 84 patients . - pubmed
Retrovirus - induced murine acquired immunodeficiency syndrome : natural history of infection and differing susceptibility of inbred mouse strains . - pubmed
C57BL mice ( Fv-1b ) develop a severe immunodeficiency disease following inoculation as adults with LP - BM5 murine leukemia virus ( MuLV ) , a derivative of Duplan - Laterjet virus which contains B - tropic ecotropic and mink cell focus - inducing MuLVs and a putative defective genome which may be the proximal cause of disease . - pubmed
By using this disease profile as a standard , the response of adult mice of various inbred strains and selected F1 hybrids was compared . - pubmed
Borrelia burgdorferi is transmitted from wild animals to humans by the bite of Ixodes dammini . - pubmed
All three feeding stages of the tick parasitize humans , though most infections are acquired from feeding nymphs in May through early July . - pubmed
White - footed mice ( Peromyscus leucopus ) are particularly important reservoirs , and in parts of southern Connecticut where Lyme disease is prevalent in humans , borreliae are universally present during the summer in these mice . - pubmed
dammini are usually indistinguishable , but strains of B. - pubmed
Ten children with recurrent tracheo - oesophageal fistula have been treated over 13 years ( 1976 - 1988 ) . - pubmed
The ventricular anti - arrhythmic action of 20 mg of betaxolol per day was evaluated in 14 patients treated in monotherapy for a fortnight , by means of repeated Holter recordings . - pubmed
The Rice-500 Leydig cell tumor of Fischer rats is associated with humoral hypercalcemia in vivo and produces a factor that stimulates cAMP formation in cultured rat osteosarcoma cells . - pubmed
The analysis shows that : ED10/5 yr and ED50/5 yr for 5 X 2.0 Gy / wk is 50 Gy and 65 Gy , respectively , for distinct telangiectasia ; The latent period , concerning both a certain frequency and degree of reaction , varies exponentially with dose level ; The latent period for 50 % of the patients , to obtain a certain score , LP50 , is correlated to that for 10 % , LP10 , with LP50 / LP10 = 2.2 + /- 0.2 ( S.D. ) - pubmed
The fractionation characteristics for telangiectasia agree well with those for animal experimental morphological and functional endpoints for late effects in different organs and support the relevance of telangiectasia as a model for predicting late effects . - pubmed
The study group consisted of 145 patients who underwent isolated coronary artery bypass grafting between January , 1980 , and July , 1985 , within 4 weeks of an acute MI . - pubmed
Postoperatively 38 patients ( 26 % ) had cardiac failure . - pubmed
Five patients , all of whom had postoperative cardiac failure , died . - pubmed
The activity of the combination of pefloxacin with ceftazidime , piperacillin , or mezlocillin was compared to the activity of the same antibiotics given alone , by measurement of serum bactericidal titres and the rate of killing of ten strains of Pseudomonas aeruginosa . - pubmed
Release of thromboxane A2 by low - dose almitrine in the hypoxic dog . - pubmed
The low almitrine dose significantly increased TXB2 levels in hypoxic beagles , but the levels remained virtually unchanged in the normoxic animals with almitrine bismesylate and in the hypoxic animals with solvent . - pubmed
Localized enamel hypoplasia of the primary canine . - pubmed
The lesion , roughly a circular area of enamel hypoplasia approximately one millimeter in diameter , occurs on the labial surface of the primary canine tooth . - pubmed
We used conjunctival impression cytology results to evaluate children with early xerophthalmia before treatment and again three to eight weeks later . - pubmed
We then compared children with early xerophthalmia to normal children . - pubmed
Conjunctival impressions from children with xerophthalmia all showed complete loss of goblet cells and the appearance of enlarged , partially keratinized epithelial cells . - pubmed
The fluid resuscitation requirements and mortality from thermal injury were reviewed in 177 children admitted to the Intermountain Burn Center over a 7 year period . - pubmed
The resuscitative mortality rate for all pediatric patients was 7 percent , the in - hospital mortality rate was 15 percent , and the 50 percent mortality burn correlate for these patients was 64 percent of the total body surface area . - pubmed
Of the 39 deaths observed , 31 occurred in the patients admitted with shock . - pubmed
Retroperitoneal hematomas in patients who are in shock , who have peritoneal irritation or positive peritoneal lavage results , should undergo operation . - pubmed
Two of the three patients reported in this study were symptomatic with blurred vision and systemic complaints . - pubmed
The fluorescein angiographic changes observed in the optic disk of patients with hypervitaminosis A are similar to those associated with other known causes of papilledema . - pubmed
Cardiac responses to autonomic nerve stimulation during acidosis and hypoxia in the lamb . - pubmed
[ Residual pulmonary lesions following primary tuberculosis in children under the age of 4 and treated with chemotherapy ] . - pubmed
Infection of chicks with recently isolated Newcastle disease viruses of low virulence . - pubmed
This paper reports the clinical and biochemical results in six patients with Hurler disease ( Mucopolysaccharidosis IH ; McKusick 25280 ) , two patients with Hunter disease ( Mucopolysaccharidosis II ; McKusick 25285 ) and one patient with Sanfilippo B disease ( Mucopolysaccharidosis IIIB ; McKusick 25292 ) who were treated by fibroblast transplantation . - pubmed
Intraluminal manometric and cine - cholangiomanometric studies were carried out on the movement of the sphincter of Oddi at the time of excretion of bile into the duodenum in 12 patients after cholecystectomy for gallstone . - pubmed
Twenty - one patients with local recurrence were treated . - pubmed
Ten patients with cutaneous metastases from head and neck primary tumors were also treated . - pubmed
However , these patients rapidly developed new tumors in areas adjacent to those previously treated . - pubmed
[ Transfer of cefsulodin into human otorrhea after intravenous administration ] . - pubmed
Serum from 20 children with urinary tract infections and proved cystitis cystica has been examined for antibody to a panel of established cell lines derived from normal urothelium and transitional cell carcinomas of the bladder . - pubmed
Antibody - dependent cytotoxicity was measured with serial dilutions of patient serum and lymphocytes from normal healthy adults as effector cells . - pubmed
The patients were grouped according to the duration of symptoms , the presence or absence of reflux , and the presence or absence of upper tract changes or scarring . - pubmed
Amyloid fibrils were isolated from the kidneys of two Japanese patients with type I FAP and fractionated on Sephadex G-100 gel column . - pubmed
Angiographically equivocal aneurysmal dilatation at the junction of the internal carotid and the posterior communicating arteries was noted in a patient with documented subarachnoid hemorrhage . - pubmed
The authors report three children who demonstrated unilateral displacement of the urinary bladder associated with acute iliofemoral vein thrombosis . - pubmed
Acute lymphoblastic leukemia in a patient with familial derivative chromosome 4 . - pubmed
To evaluate the possible lack of the elimination of ischemia with sublingual nitroglycerin , we studied 25 male patients with stable angina pectoris who underwent exercise stress testing with recording of blood pressure , pulse , and ST - segment displacement . - pubmed
All 25 patients had angina and ischemic ST - segment changes in the first stress test . - pubmed
On repeat stress testing , 15 patients had angina and ST - segment changes , 2 patients had angina but no ST - segment changes , and 4 patients had no ST - segment changes and no angina . - pubmed
Four patients , however , had no angina but persistent ischemic ST - segment changes suggesting that angina was converted into silent ischemia . - pubmed
Inclusion body myositis developed in two men , 36 and 48 years old with long - standing common variable immunodeficiency . - pubmed
We conclude that inclusion body myositis can develop in patients with common variable immunodeficiency . - pubmed
Anthelmintic suppression of Fasciola hepatica infections in sheep . - pubmed
In an experiment to examine the use of anthelmintics to suppress the faecal egg output of Fasciola hepatica from sheep and reduce the prevalence of infection on a sheep farm with a history of chronic fasciolosis , triclabendazole was administered four times annually for three years . - pubmed
Peripheral blood lymphocytes were obtained from eight untreated patients suffering from long - standing plaque - type psoriasis 1 h following UVB treatment and at the end of 15 UVB treatments . - pubmed
In addition homozygous mice also demonstrated fasting hyperglycemia , impaired glucose tolerance and reduced fecundity . - pubmed
Calculating economic injury levels for stable flies ( Diptera : Muscidae ) on feeder heifers . - pubmed
A procedure for calculating the economic injury levels for stable flies , Stomoxys calcitrans ( L. ) , on feeder heifers was developed from reduction of average daily weight gain - stable fly population level data in 8 independent replicated experiments over 17 yr . - pubmed
Recent imaging studies in patients with head injury suggest that the development of traumatic brain oedema may follow a biphasic time course similar to that of ischaemic oedema . - pubmed
Human immunodeficiency virus type 1 infection of cells and tissues from the upper and lower human female reproductive tract . - pubmed
Viable tissue sections and isolated cell cultures from the human fallopian tube , uterus , cervix , and vaginal mucosa were examined for susceptibility to infection with human immunodeficiency virus type 1 ( HIV-1 ) . - pubmed
We examined infectivity by using the monocytotropic strain HIV-1(JR - FL ) and several primary isolates of HIV-1 obtained from infected neonates . - pubmed
Female reproductive tract cells required a minimum of 60 min of exposure to HIV-1 in order for infection to occur , in contrast to peripheral blood lymphocytes , which became infected after being exposed to HIV-1 for only 1 min . - pubmed
These findings demonstrate that HIV-1 can infect cells and tissues from different sites within the female reproductive tract and suggest that multiple cell types , including epithelial cells , may be targets for the initial infection by HIV-1 . - pubmed
Nineteen patients had a single functioning kidney , 23 had a bilateral stenosis , which was stented bilaterally in 11 , and 8 had a unilateral stenosis . - pubmed
A pronounced thymic B cell deficiency in the spontaneously diabetic BB rat . - pubmed
Effects of positive feedback on the social interactions of boys with attention deficit hyperactivity disorder : a test of the self - protective hypothesis . - pubmed
METHODS : A total of 12 ELBW infants ( mean birth weight , 672 + /- 95 g ; mean gestation , 26 + /- 2 weeks ) served as their own controls in this prospective study comparing physiologic parameters during bottle and breastfeeding . - pubmed
Decreased serum and intracellular levels of magnesium have been reported in patients with migraine . - pubmed
We measured ionized magnesium , cyclic AMP ( adenosine monophosphate ) , and cyclic GMP ( guanosine monophosphate ) in platelets of patients with migraine , in patients with tension - type headache , and in healthy controls . - pubmed
The platelet level of ionized magnesium from patients with tension - type headache was significantly lower than the levels from the other two groups . - pubmed
The platelet level of cyclic AMP from patients with migraine was higher than those from the other groups . - pubmed
It is suggested that reduced platelet ionized magnesium in patients with tension - type headache is related to abnormal platelet function , and that increased platelet cyclic AMP in patients with migraine is related to alteration of neurotransmitters in the platelet . - pubmed
It has been reported , however , that a prototype of dihydropyridines , nifedipine , does not reduce mortality of patients with ischemic heart disease , possibly because of reflex stimulation of the sympathetic nervous system . - pubmed
Amlodipine ( 8 mg / kg per day , once a day ) or nifedipine ( 24 mg / kg per day , three times a day ) was administered to spontaneously hypertensive 12 - week - old rats for 12 weeks . - pubmed
Standardization of the lactulose - mannitol test in rats : application to burn injury . - pubmed
These results corroborate those obtained in burn patients and show that our model is suitable for further experiments on nutritional manipulation . - pubmed
Over the past decade , various studies have demonstrated that class I antiarrhythmic drugs should be avoided in patients with heart failure , cardiac ischaemia or a previous myocardial infarction . - pubmed
In contrast , class II drugs ( beta - blockers ) reduce morbidity and may even lower mortality in patients suffering from moderate to severe heart failure . - pubmed
If in the setting of heart failure ventricular arrhythmias are symptomatic and/or sustained , patients can be treated effectively , after appropriate treatment of the underlying disease , with the class III drug amiodarone . - pubmed
Finally , an implantable cardioverter defibrillator seems to improve overall survival in patients with life - threatening ventricular arrhythmias . - pubmed
Between 1992 and 1996 , 73 acute humeral shaft fractures in 71 patients were treated with antegrade Russell - Taylor humeral nailing . - pubmed
Three patients had preoperative brachial artery injuries , and 12 had preoperative nerve palsies . - pubmed
All patients without full return of elbow and shoulder function had concomitant injuries . - pubmed
Antegrade Russell - Taylor nailing is an acceptable alternative for the treatment of acute humeral shaft fractures in multiply injured patients . - pubmed
The type species of the genus is Sulfurisphaera ohwakuensis , and the type strain of the species is TA-1 T (= IFO 15161 T ) . - pubmed
Metastatic bone disease is a frequent cause of morbidity in advanced cancer patients with a subsequent high incidence of skeletal complications ( fractures , hypercalcemia , spinal cord compression ) and severe pain . - pubmed
The aim of this review of the literature is to show the analgesic efficacy of the different bisphosphonates in phase III studies carried out on patients with metastatic bone disease . - pubmed
From the analysis of the published studies it appears that bisphosphonates and , in particular , intravenous Disodium Pamidronate , are not only able to slow down the progression of the disease and to reduce the onset of skeletal complications but also have an analgesic effect and the possibility of improving the quality of life , above all in patients with osteolytic metastases due to breast cancer and multiple myeloma . - pubmed
Bisphosphonates represent a further valid therapy to add to an already consolidated list of therapies such as radio , chemo and endocrine therapy , analgesic drugs , orthopaedic and physiatric in the pain management of patients with bone metastases . - pubmed
It still remains to be seen if the newer and more potent bisphosphonates such as Ibandronate and Zoledronate can be administered differently from the intravenous route such as by mouth or by patch which are readily accepted by the patient and , moreover , if these more potent drugs are able to prevent or delay the onset and/or the progression of bone metastases . - pubmed
On the other hand , hypothyroidism may be diagnosed in patients after radioiodine therapy , external radiotherapy to the neck and partial or subtotal thyroidectomy . - pubmed
Between January 1980 and December 1996 , 36 patients with metachronous liver metastases who underwent hepatic resection were reviewed . - pubmed
This open study comprised 22 patients with type I or type II diabetes and 16 patients with leg or ankle ulcers of different aetiologies . - pubmed
This study used an animal model to investigate the importance of the time at which testing occurs for age differences in learning and memory . - pubmed
Many patients treated with breast conservation undergo reexcision to obtain clear margins although the relationship between clear margins and local recurrence remains controversial . - pubmed
Reexcision was significantly related to diagnostic method ( spot localization 63 % , excisional biopsy 36 % , fine - needle aspiration 10 % ; P & lt;0.001 ) , first margin status ( clear 0 % , close 11 % , positive 46 % , unknown 48 % ; P & lt;0.001 ) , patient age ( 54 years for reexcised patients and 58 for non - reexcised patients ; P & lt;0.001 ) , and tumor size ( mean tumor size 1 . - pubmed
Patients undergoing reexcision were significantly more likely to be diagnosed by spot localization , have nonnegative excisional biopsy margins , be younger , and have smaller tumors than patients not undergoing reexcision . - pubmed
Local recurrence was not significantly related to margin status ( 8 % with clear margins , 7 % with positive margins , 19 % with close margins , and 11 % with unknown margins ) or reexcision ( 10 % local recurrence rate for patients with negative final margins after reexcision and 12 % with positive , close or unknown first margin without reexcision ) . - pubmed
For patients with nonnegative margins , reexcision was more commonly performed in young patients with small tumors diagnosed by spot localization biopsy . - pubmed
Puumala hantavirus ( PUUV ) causes nephropathia epidemica ( NE ) , a form of haemorrhagic fever with renal syndrome that occurs in northern and central Europe . - pubmed
Alcohol consumption induces hepatocyte apoptosis in patients with chronic hepatitis C infection . - pubmed
The aim of this study was to evaluate the relationship between alcohol consumption and hepatocyte apoptosis in hepatitis C - infected patients . - pubmed
RESULTS : Hepatocyte apoptosis was significantly greater in hepatitis C - infected patients than in controls . - pubmed
CONCLUSIONS : This study confirms that both hepatitis C infection and ethanol consumption induce hepatocyte apoptosis in humans . - pubmed
Previous studies showed that two groups of Trypanosoma cruzi clonal genotypes named clonet 20 and clonet 39 were predominant in Triatoma infestans , the unique vector of Chagas disease in Bolivia . - pubmed
We examined sections of brain , spinal cord , spinal roots , and peripheral nerves from a patient with paraneoplastic syndrome in the course of lung adenocarcinoma . - pubmed
These carnobacteria strains were also screened for their ability to produce growth inhibitory compounds active against the fish pathogens Aeromonas salmonicida subsp . - pubmed
METHOD : Thirteen patients with inoperable oesophagus cancer were treated between 1995 - 98 . - pubmed
Side effects : Oesophagitis of different degree occurred in all patients , consecutive transitory dysphagia developed in 9/27 ( 33.3 % ) patients . - pubmed
OBJECTIVE : The objective was to evaluate prospectively the role of hyperventilation in the development of neurocardiogenic syncope in children during head - upright tilt testing ( HUTT ) . - pubmed
STUDY DESIGN : Tilt testing was performed in 34 children ( mean age 10.6 years ) with clinical suspicion of syncope . - pubmed
RESULTS : Tilt test was negative in 12 cases ; 3 ( 25 % ) patients of this group exhibited hyperventilation any time during the test . - pubmed
In the remaining 22 cases the HUTT was positive , and 15 ( 68.2 % ) patients of this group exhibited hyperventilation at the onset of clinical symptoms and during syncope . - pubmed
CONCLUSIONS : Spontaneous hyperventilation could play a relevant role in the pathophysiology of pediatric neurocardiogenic syncope , and it could point out a specific subtype of response to orthostatic stress in susceptible patients . - pubmed
We suggest the inclusion of capnography in tilt - test protocols could improve the assessment of syncope in children . - pubmed
A total of 69 patients were treated for ACC from 1955 to 1999 . - pubmed
One patient , who presented with fatal brain metastasis , was excluded from further analysis . - pubmed
This abnormality , most evident when the system is activated by a low - salt diet , is a cardinal feature of the syndrome of nonmodulation , affecting a large percentage of white hypertensive patients . - pubmed
This study investigated whether young black women are likewise spared its expression or whether the adrenal unresponsiveness common among black hypertensive patients is unaccompanied by a gender bias . - pubmed
For this purpose we developed methods to determine the in vitro oxidizability of cerebrospinal fluid and plasma lipoproteins of Alzheimer patients . - pubmed
Cerebrospinal fluid and plasma lipoprotein oxidation was found to be increased in Alzheimer 's patients compared to controls and a corresponding decrease of antioxidant vitamins was found . - pubmed
In a pilot study , in vitro lipoprotein oxidation in cerebrospinal fluid of Alzheimer patients could be delayed by vitamin E and C supplementation . - pubmed
After six weeks , these mice were challenged with 4T(1 ) and Lewis cancer cells . - pubmed
The inhibition of the tumor and the survival time of the mice were also investigated . - pubmed
CONCLUSIONS : Malignant germ cell tumors arising in the abdomen and retroperitoneum have an excellent prognosis despite advanced stage in most children . - pubmed
Analysis of systematic effects on congenital sensorineural deafness in German Dalmatian dogs . - pubmed
We have analysed the systematic influences , phenotypic colour markers and the additive genetic variation for congenital sensorineural deafness ( CSD ) in German Dalmatian dogs in order to help elucidate the importance of phenotypic breed characteristics for genetic differences of CSD . - pubmed
The heritability estimate for CSD in German Dalmatian dogs was h(2)=0.27+/-0.07 . - pubmed
Levels of enzymes of the direct oxidative pathway of carbohydrate metabolism in mammalian tissues and tumours . - pubmed
Alpha - Naphthylthiourea ( ANTU ) as a cause of poisoning in dogs and its chemical identification in material of animal origin . - pubmed
RHEUMATIC FEVER IN CHILDREN AND ADOLESCENTS . - pubmed
[ Efficacy of pretreatment with Serenoa repens on bleeding associated with transurethral resection of prostate ] . - pubmed
CONCLUSION : The pretreatment with Serenoa repens , before TURP procedure , improves the efficacy of the procedure itself and reduces the risk of complications , in particular perioperative bleeding and duration of postoperative catheterization . - pubmed
Human studies are needed to evaluate the clinical utility of rofecoxib treatment in breast or prostate cancers . - pubmed
Male rats exposed for 21 days to high altitude ( 4,340 m ) responded with arrest of weight gain and increased hematocrit and testosterone levels . - pubmed
The present study tested the extension of errorless learning for deficits in social problem - solving skills in patients with schizophrenia . - pubmed
METHOD : Sixty clinically stable outpatients with schizophrenia or schizoaffective disorder were stratified by gender and level of memory impairment before being randomly assigned to one of two training programs : errorless learning or symptom management . - pubmed
RESULTS : Paramedics completed 100 MASS assessments for 73 ( 73 % ) stroke / transient ischemic attack patients and 27 ( 27 % ) stroke mimics . - pubmed
It distinguishes stroke mimics , with good recognition of suitable patients for thrombolytic therapy . - pubmed
The study was carried out on 92 patients with otosclerosis , ( 17 M , 75 F ) , median age 41 years ( range 25 - 56 ) , undergoing stapedotomy . - pubmed
More patients in the daclizumab group than in the placebo group died of infection ( 6 vs. 0 ) when they received concomitant cytolytic therapy . - pubmed
Despite the availability of several classes of drugs against acquired immunodeficiency syndrome ( AIDS ) caused by human immunodeficiency virus type 1(HIV-1 ) , this deadly disease showing very little sign of containment , especially in Sub - Saharan Africa and South - East Asia . - pubmed
OBJECTIVE : This study was undertaken to evaluate whether the effects of hyperbaric oxygen ( HBO ) therapy could alter the critical size for spontaneous healing of a bone defect in the rabbit calvarial model . - pubmed
HBO may have increased the diameter of the rabbit critical - sized calvarial defect to more than 18 mm . - pubmed
PATIENTS AND METHOD : We included a total of 190 diabetic patients from a primary care center , without coronary heart disease , in whom the coronary risk could be calculated before 1 January 1995 . - pubmed
Impact of metabolic syndrome on myocardial perfusion grade after primary percutaneous coronary intervention in patients with acute ST elevation myocardial infarction . - pubmed
AIMS : Metabolic syndrome with its associated cardiovascular risk factors and prothrombotic , procoagulant and proinflammatory properties and its detrimental effects on coronary microcirculation may play a role in the occurrence of poor myocardial perfusion after primary percutaneous coronary intervention in patients with acute myocardial infarction . - pubmed
Accordingly , this study was designed to evaluate the association between metabolic syndrome and myocardial perfusion grade in patients with acute myocardial infarction undergoing primary percutaneous coronary intervention . - pubmed
MATERIAL AND METHODS : The study population included 283 consecutive patients ( 229 men , mean age=62+/-8 years ) admitted to our hospital with ST - elevation myocardial infarction and who underwent primary percutaneous coronary intervention . - pubmed
RESULTS : The prevalence of metabolic syndrome was found to be significantly higher in patients with poor myocardial perfusion than in those with good myocardial perfusion ( 40 vs. 20 % , respectively , P=0.002 ) . - pubmed
CONCLUSIONS : We have shown , for the first time , a significant association between metabolic syndrome and impaired myocardial perfusion after percutaneous coronary intervention in patients with acute myocardial infarction . - pubmed
This data may partially explain the poor short and long - term outcomes of acute myocardial infarction in patients with metabolic syndrome . - pubmed
Human monocytic ehrlichiosis and human granulocytic anaplasmosis in the United States , 2001 - 2002 . - pubmed
The epidemiologic features are described of cases of human monocytic ehrlichiosis and human granulocytic anaplasmosis in the United States . - pubmed
Aerobic bacterial cultures of the tympanic cavity of the middle ear were performed in eight eastern box turtles ( Terrapene carolina carolina ) with aural abscesses and 15 eastern box turtles without aural abscesses ( controls ) that were admitted to The Wildlife Center of Virginia , Virginia , USA during 2003 . - pubmed
Morganella morganii ( n = 2 ) was the only species isolated from the tympanic cavity of more than one turtle with aural abscesses . - pubmed
All nucleotide sequences were homologous to Rickettsia africae , the agent of African tick - bite fever ( ATBF ) . - pubmed
The purine salvage pathway of Anopheles gambiae , a mosquito that transmits malaria , has been identified in genome searches on the basis of sequence homology with characterized enzymes . - pubmed
PBLs exposed to oxidative stress showed a higher percentage of apoptotic cells in PD patients than in controls . - pubmed
However in cells of PD patients , the increase of apoptotic response was lower than in controls , suggesting that cells of PD patients have greater " resistance " to oxidative stress . - pubmed
Morphological alterations in skeletal muscle of spontaneously hypertensive rats . - pubmed
Lymphoproliferative disease of turkeys 1 . - pubmed
Several outbreaks of a lymphoproliferative disease of turkeys were investigated . - pubmed
Novel vasodilatory effect of intracisternal injection of magnesium sulfate solution on spastic cerebral arteries in the canine two - hemorrhage model of subarachnoid hemorrhage . - pubmed
The present study investigated the effect of intracisternal injection of MgSO4 solution on cerebral vasospasm in a canine model of subarachnoid hemorrhage ( SAH ) . - pubmed
METHODS : Subarachnoid hemorrhage was induced in 10 beagles using the two - hemorrhage model . - pubmed
CONCLUSIONS : Intracisternal injection of MgSO4 solution causes significant dilation of spastic cerebral arteries in the canine two - hemorrhage model of SAH . - pubmed
A short note on the identification of the organisms found in bovine mastitis in U.S.A. - pubmed
Not without cause : Vibrio parahaemolyticus induces acute autophagy and cell death . - pubmed
Here we discuss possible roles for the induction of autophagy during infection and discuss how V. - pubmed
MATERIALS AND METHODS : Within 61 months 39 patients ( 23 male , 16 female , 7 - 53 years , mean 18.7 years , median 17 years ) suffering from osteoid osteoma were treated . - pubmed
In 3 of 38 patients relapse occurred after 1 , 14 and 32 months and RFA was repeated . - pubmed
Uterine adenomyosis in an orang - utan ( Pongo abelii / pygmaeus ) . - pubmed
A 48 - year - old , multiparous , female hybrid orang - utan ( Pongo abelii / pygmaeus ) was investigated after a 3 - year history of irregular and excessively heavy menstrual bleeding . - pubmed
There have been few reports of uterine adenomyosis in non - human primates and none reported in an orang - utan . - pubmed
Uterine adenomyosis should be considered in the differential diagnosis in any multiparous , aged , non - human female primate with irregular and excessively heavy menstrual bleeding , and hysterectomy with bilateral salpingo - ovariectomy is recommended as a diagnostic and therapeutic solution . - pubmed
229 patients underwent follow - up MRI with intravenous contrast , 29 of which showed persistent uptake into myomata . - pubmed
Bumetanide delayed the occurrence , and reduced the number of full motor seizures during kindling , and prevented the development of kindling - induced enhanced seizure susceptibility in a majority of animals . - pubmed
METHODS : Forty - five patients ( 35 men , age = 62 + /- 15 years ) with RA atypical atrial flutter ( n = 15 , group 1 ) , RA atrial fibrillation ( AF ; n = 15 , no PV initiating foci , group 2 ) , and LA AF ( n = 1 5 , no RA arrhythmias , group 3 ) referred for three - dimensional EnSite mapping were included . - pubmed
The basis of the differential ability of these two IHNV genogroups to cause disease in rainbow trout was investigated in live infection challenges with representative U and M IHNV strains . - pubmed
Analyses of in vivo replication showed that U IHNV consistently had lower prevalence and lower viral load than M IHNV during the course of infection . - pubmed
We investigated the effects of genetic background on the phenotype of embryonic lethality that occurs in a mouse model for MEN1 . - pubmed
Thus , an increased level of D - serine resulting from decreased catalysis corrected the performance of mice with deficient NMDAR glycine site activation in behavioral tasks relevant to the negative and cognitive symptoms of schizophrenia . - pubmed
The association between Streptococcus bovis and bowel neoplasia has been frequently reported . - pubmed
These two case reports highlight the possibility of hematogenous seeding of arthroplasty components by Streptococcus bovis in patients with colonic neoplasia . - pubmed
STUDY OBJECTIVE : The purpose of this randomized controlled trial was to determine the immediate and delayed effects of noninvasive ventilation for patients in acute cardiogenic pulmonary edema ( ACPE ) in addition to aggressive usual care in a medical prehospital setting . - pubmed
METHODS : Out - of - hospital patients in severe ACPE were eligible for the study . - pubmed
boulardii is distributed in lyophilized form in many countries and used for the prevention of diarrhea in children and adults , including Clostridium difficile ( C. - pubmed
A hallmark of inflammation , and a consistent observation in patients with ALI , is a perturbation in the systemic redox environment . - pubmed
Nitrogen - containing bisphosphonates have been associated with the development of osteonecrosis of the jaws ( ONJ ) , but the lack of reliable epidemiological data and appropriate animal models has restricted our understanding of ONJ pathophysiology and limited its management . - pubmed
This study investigates the use of omega-3 fatty acid - enriched lipid emulsions in ARDS patients and their effects on eicosanoid values . - pubmed
METHODS AND PATIENTS : Patients ( n = 536 ) with chronic HF , ejection fraction & lt;50 % and LV end - diastolic volume index & gt;91 mL / m(2 ) , classified according to LV mass index and relative wall thickness ( RWT ) , were followed up for 33 + - 21 months . - pubmed
CONCLUSION : In patients with systolic HF , an independent and incremental risk of adverse outcome was associated with increased mass index and decreased RWT . - pubmed
Rapid thrombelastography ( r - TEG ) delivers a more comprehensive assessment of the coagulation system but has not been prospectively validated in trauma patients . - pubmed
We have evaluated the benefits of a dedicated Pediatric Cardiac Intensive Care Unit ( PCICU ) in the early postoperative outcomes of patients undergoing surgery for congenital heart disease . - pubmed
H1N1 pneumonia : our experience in 50 patients with a severe clinical course of novel swine - origin influenza A ( H1N1 ) virus ( S - OIV ) . - pubmed
PURPOSE : The authors reviewed chest radiographs ( CXR ) and thin - section computed tomography ( CT ) findings of pulmonary complications in a selected population of 50 consecutive patients with severe novel swine - origin influenza A ( H1N1 ) virus ( S - OIV ) pneumonia who were seen at the Subintensive Respiratory Unit ( UTSIR ) and at the Intensive Care Unit ( ICU ) at Monaldi Hospital , Naples , Italy . - pubmed
Thoracic comorbidity was present in 18 % of patients ; 22 % of patients was obese , and in this group , the clinical course was more aggressive than in the others with the same lesion extent at imaging . - pubmed
On MDCT , ground - glass opacities and areas of consolidation had a predominant peribronchovascular and subpleural distribution , resembling organising pneumonia ; they progressed to bilateral extensive airspace disease in severely ill patients . - pubmed
CONCLUSIONS : This case report suggests a new possible syndromic association between ADEM and FUO , which should be considered in the clinical examination of patients with FUO , especially in the presence of also modest neurologic or neuropsychiatric symptoms . - pubmed
The present study used diffusion tensor imaging ( DTI ) to investigate whether occult brain damage exists in RNMO patients . - pubmed
DTI scans using a 3.0 T MRI scanner were performed in 24 clinically confirmed RNMO patients whose conventional brain MRI results were normal , and also in 24 age- and sex - matched healthy control subjects . - pubmed
Both acute and stable NMO patients had a higher average FA in ROIs of the thalamus and putamen . - pubmed
Acute NMO patients had significantly higher average MDs than controls in the genu of corpus callosum and optic radiation , and significantly lower average MDs in the medulla oblongata . - pubmed
Stable NMO patients had increased MDs in the genu of corpus callosum and optic radiation , but lower MDs in the medulla oblongata , internal capsule and thalamus . - pubmed
Whey protein enhances normal inflammatory responses during cutaneous wound healing in diabetic rats . - pubmed
Thus , the aim of this study was to determine whether dietary supplementation with WP could enhance normal inflammatory responses during wound healing in diabetic rats . - pubmed
In addition , the time required for wound healing was significantly prolonged in diabetic rats . - pubmed
WP was found to significantly decrease the time required for wound healing in WDWP rats . - pubmed
Optic nerve lesions in diabetic rats : blood flow to the optic nerve , permeability of micro blood vessels and histopathology . - pubmed
METHODS : Male Wistar rats ( n=20 ) were randomly divided into control and diabetic groups . - pubmed
RESULTS : Diabetic rats had atrophic optic nerve fibers with neurite swelling , loss of myelin , and a greater - than - normal proliferation of astrocytes , occurring within 3 months of induction of diabetes . - pubmed
Blood flow to the optic nerve was lower in diabetic rats than in controls . - pubmed
Microvessel permeability in diabetic rats increased 2.03 - fold compared to controls . - pubmed
CONCLUSION : Diabetic rats develop significant pathological changes in the optic nerve , reduced blood flow to the optic nerve and increase microvessel permeability . - pubmed
RESULTS : PCa has been detected in 71 ( 49.3 % ) patients . - pubmed
Non - dipping pattern in untreated hypertensive patients is related to increased pulse wave velocity independent of raised nocturnal blood pressure . - pubmed
Hypertensive patients were diagnosed according to ambulatory BP measurements ( mean BP & gt;= 130/80 mmHg ) . - pubmed
Eighty - four hypertensive patients , consulted for initial evaluation of hypertension , were enrolled . - pubmed
Patients with the history of any cardiovascular disease were excluded from the study . - pubmed
Palliative and end - of - life care for patients with idiopathic pulmonary fibrosis : challenges and dilemmas . - pubmed
Fifty - five patients ( seven men ) had 64 adenomas and 26 focal nodular hyperplasias ( FNHs ) resected . - pubmed
Impact of nasal polyps on quality of life of chronic sinusitis patients . - pubmed
METHODS : Retrospective analysis of prospectively collected data comparing two groups of patients diagnosed with CRS with and without polyps who underwent surgery with a minimum of 3 month follow up period . - pubmed
RESULTS : 30 patients underwent surgical management of CRS over a period of one year . - pubmed
Polyps were present in 15 patients with CRS while , the other 15 did not have polyps . - pubmed
6 patients required revision surgery ( 20 % ) , 3 ( 10 % ) belonging to polyp group and 3 ( 10 % ) who did not have polyps . - pubmed
CONCLUSION : Nasal Polyp has a significant negative impact on the patients with CRS . - pubmed
Patients with polyps have higher symptom scores , worse objective findings compared with patients without polyp , but patients with polyp show more improvement after surgical intervention and need for revision surgery is equal in both groups . - pubmed
VSLI recently received accelerated FDA approval for use in adults with advanced , relapsed and refractory Philadelphia chromosome - negative ALL and is in development for untreated adult ALL , pediatric ALL and untreated aggressive NHL . - pubmed
The Use of NeuroAiD ( MLC601 ) in Postischemic Stroke Patients . - pubmed
We aimed to assess the efficacy of MLC601 on functional recovery in patients given MLC601 after an ischemic stroke . - pubmed
This is a retrospective cohort study comparing poststroke patients given open - label MLC601 ( n = 30 ; 9 female ) for three months and matching patients who did not receive MLC601 from our Stroke Data Bank . - pubmed
Our results show that HIV-1 infection in Bulgaria reflects the shifting distribution of genotypes coincident with the changing epidemiology of the HIV-1 epidemic among different risk groups . - pubmed
Furthermore , the substantial and increasing HIV-1 genetic heterogeneity , combined with fluctuating infection dynamics , highlights the importance of sustained and expanded surveillance to prevent and control HIV-1 infection in Bulgaria . - pubmed
Differential gene expression related to Nora virus infection of Drosophila melanogaster . - pubmed
Nora virus is a recently discovered RNA picorna - like virus that produces a persistent infection in Drosophila melanogaster , but the antiviral pathway or change in gene expression is unknown . - pubmed
This genome - wide expression profile of Nora virus infection of D. - pubmed
Titers to avian influenza virus antigens increased with age and with geometric mean antibody titer to human influenza virus antigens . - pubmed
To verify the usefulness of 8 - OH - Gua , the 8 - OH - dG and 8 - OH - Gua levels in the urine and the 8 - OH - Gua levels in the serum of type 2 diabetic model animals , db / db mice , were measured as oxidative stress markers by a column switching HPLC - system coupled to an electrochemical detector . - pubmed
Although no difference was observed in the 8 - OH - dG levels in the liver and kidney DNA between the diabetic and control mice , these results suggested that urinary 8 - OH - dG and free base 8 - OH - Gua in urine or serum may be good biomarkers of oxidative stress . - pubmed
Optimal utilization and management of implanted cardiac rhythm devices in patients hospitalized for heart failure . - pubmed
Improved utilization and optimization of device therapy in the management of patients with decompensated heart failure ( HF ) is an important clinical priority . - pubmed
Evaluation and optimization of cardiac resynchronization therapy should be considered in all patients admitted with HF despite cardiac resynchronization therapy . - pubmed
Co - treatment of rats repeatedly given therapeutic doses of Dcl for 7 days with a single dose of LPS 2h before the last Dcl dose resulted in severe liver toxicity . - pubmed
Thrombus volume is similar in patients with ruptured and intact abdominal aortic aneurysms . - pubmed
The aim of this study was to compare the volume of ILT in patients with ruptured and intact AAAs . - pubmed
METHODS : We matched by maximum axial diameter alone , on a 1:2 basis , 28 patients with ruptured AAAs and 56 patients with intact AAAs . - pubmed
The Mann - Whitney U test was used to compare ILT volumes between patients with ruptured and intact AAAs . - pubmed
PTLD developed in 43 patients ( 1.0 % ) of 4205 pancreas transplants . - pubmed
Patient survival was significantly decreased in patients with PTLD , with a one- , three- , and five - yr survival of 91 % , 76 % , and 70 % , compared with 97 % , 93 % , and 88 % in patients without PTLD ( p & lt ; 0.001 ) . - pubmed
Patients with the risk factors identified should be monitored closely for the development of PTLD . - pubmed
Clinical examination protocol to detect atypical and classical scrapie in sheep . - pubmed
Unless a random sample of the sheep or goat population is actively monitored for scrapie , identification of scrapie cases relies on the reporting of clinical suspects , which is dependent on the individual 's familiarization with the disease and ability to recognize clinical signs associated with scrapie . - pubmed
To aid in the identification of clinical suspects , a short examination protocol is presented to assess the display of specific clinical signs associated with pruritic and nonpruritic forms of TSEs in sheep , which could also be applied to goats . - pubmed
This may lead to a more detailed neurologic examination of reporting animals as scrapie suspects . - pubmed
It could also be used in experimental TSE studies of sheep or goats to evaluate disease progression or to identify clinical end - point . - pubmed
Outcome and prognostic factors in patients with mantle - cell lymphoma relapsing after autologous stem - cell transplantation : a retrospective study of the European Group for Blood and Marrow Transplantation ( EBMT ) . - pubmed
BACKGROUND : Autologous stem - cell transplantation ( autoSCT ) is considered a standard treatment of non - frail patients with mantle cell lymphoma ( MCL ) , but little is known about outcome of MCL patients relapsing after autoSCT . - pubmed
PATIENTS AND METHODS : Patients with MCL were eligible if they had relapsed after autoSCT performed between 2000 and 2009 . - pubmed
CONCLUSIONS : MCL recurrence within 1 year after autoSCT has an extremely dismal outcome , while the prognosis of patients with longer remission durations after autoSCT is significantly better . - pubmed
METHODS : Between April 2003 and April 2011 , 88 patients with small lung lesions which were clinically diagnosed as primary lung cancer were treated with SBRT . - pubmed
RESULTS : Recurrence was observed in 13 patients . - pubmed
Two patients ( 2.3 % ) had Grade 2 radiation pneumonitis , and six patients ( 6.8 % ) had Grade 2 rib fractures . - pubmed
A list of the 70 species of Australian ticks ; diagnostic guides to and species accounts of Ixodes holocyclus ( paralysis tick ) , Ixodes cornuatus ( southern paralysis tick ) and Rhipicephalus australis ( Australian cattle tick ) ; and consideration of the place of Australia in the evolution of ticks with comments on four controversial ideas . - pubmed
We use an image - matching system much like the image - matching systems of field guides to birds and flowers to identify Ixodes holocyclus ( paralysis tick ) , Ixodes cornuatus ( southern paralysis tick ) and Rhipicephalus ( Boophilus ) australis ( Australian cattle tick ) . - pubmed
holocyclus ( paralysis tick ) from the first paper on the biology of an Australian tick by Bancroft ( 1884 ) , on paralysis of dogs by I. - pubmed
Limited role of regulatory T cells during acute Theiler virus - induced encephalitis in resistant C57BL/6 mice . - pubmed
However , very little is known about the role of Tregs in regulating antiviral responses during acute encephalitis in resistant mouse strains . - pubmed
RESULTS : As expected , DEREG mice that are on a C57BL/6 background were resistant to TMEV infection and cleared the virus within days of infection , regardless of the presence or absence of Tregs . - pubmed
CONCLUSION : We therefore propose that unlike susceptible mice strains , interfering with the Treg compartment of resistant mice only has negligible effects on virus - induced pathologies in the CNS . - pubmed
Comparison of effect of granules and herbs of Bu - Shen - Yi - Qi - Tang on airway inflammation in asthmatic mice . - pubmed
The aim of this study was to compare the effect of granules and herbs of BSYQT on airway inflammation in asthmatic mice . - pubmed
[ Impairments of rats ' behavioral reactions , concentration of corticosterone and expression of cytokine 's gene under experimental postviral fatigue ] . - pubmed
OBJECTIVE : We present a clinical and genetic study of four children of Pakistani descent with similar clinical presentations and treatment course , each of whom suffers from a severe pustular dermatosis , initially described as a pustular variant of psoriasis . - pubmed
MATERIAL AND METHODS : The study sample consisted of 19 drug - free cluster headache patients ( 16 males , three females ) and 19 healthy volunteers . - pubmed
Dysautonomic symptoms were evaluated during attack and remission periods of cluster headache patients . - pubmed
Face sympathetic skin responses might be more sensitive compared to extremity sympathetic skin response in demonstrating dysautonomic symptoms in cluster headache patients . - pubmed
Experimental microembolism induces localized neuritic pathology in guinea pig cerebrum . - pubmed
Microbleeds are a common finding in aged human brains . - pubmed
Here we used a guinea pig model of cerebral microembolism to explore a potential inductive effect of vascular injury on neuritic and amyloid pathogenesis . - pubmed
These experimental data suggest that microvascular injury can induce multisystem neuritic pathology associated with an enhanced amyloidogenic potential in wild - type mammalian brain . - pubmed
Time - series data were acquired in 58 patients with early to moderate stage Parkinson ' s disease and 54 healthy controls , and analyzed by Scaled Subprofile Model Principal Component Analysis toolbox . - pubmed
Of 10,261 patients with type 2 diabetes who survived to the end of a randomized ADVANCE trial 83 % were included in the ADVANCE - ON project for observation for 6 years . - pubmed
The results can be related to gradually weakening protective effect of perindopril / indapamide combination on cardiovascular system , and are indicative of the expedience of long - term use of this antihypertensive therapy for maximal lowering of mortality of patients with diabetes . - pubmed
METHODS : From a pool of patients with cone - beam computed tomography scans who came for orthodontic treatment , a sample of 133 patients was identified , with 54 in posterior crossbite ( 28 boys , 26 girls ) and 79 not in crossbite ( 77 boys , 110 girls ) . - pubmed
METHODS : A systematic literature review was performed to retrieve randomised controlled trials in patients with COPD or asthma that studied the in - company evolution of inhaler devices . - pubmed
Metabolomics Identifies Biomarker Pattern for Early Diagnosis of Hepatocellular Carcinoma : from Diethylnitrosamine Treated Rats to Patients . - pubmed
In addition to glial cells , HIV-1 infection occurs in multipotent human neural precursor cells ( hNPCs ) and induces quiescence in NPCs . - pubmed
HIV-1 infection of the brain alters hNPC stemness , leading to perturbed endogenous neurorestoration of the CNS following brain damage by HIV-1 , compounding the severity of dementia in adult neuroAIDS cases . - pubmed
Relating Histopathology and Mechanical Strain in Experimental Contusion Spinal Cord Injury in a Rat Model . - pubmed
The aim of this study is to determine a relationship between these internal strains during SCI and primary damage to spinal cord gray matter ( GM ) in an in vivo rat contusion model . - pubmed
Using magnetic resonance imaging and novel image registration methods , we measured three - dimensional ( 3D ) mechanical strain in in vivo rat cervical spinal cord ( n = 12 ) during an imposed contusion injury . - pubmed
METHODS : We imaged fresh brain slices from 21 MS patients using 1.5 T scanners . - pubmed
This can be critical for monitoring disease activity and assessing remyelination therapies for MS patients . - pubmed
To the best of our knowledge , this is the first case report in the literature of a patient with MFH within the abductor pollicis longus ( APL ) muscle . - pubmed
A 79 - year - old Caucasian man presented with a swelling in the middle third of the dorsal aspect of the left forearm . - pubmed
[ Occurrence and clinical characteristics of sleep apnea syndrome in heart failure patients with atrial fibrillation ] . - pubmed
OBJECTIVE : To evaluate the occurrence and clinical characteristics of sleep apnea syndrome ( SAS ) in heart failure ( HF ) patients with atrial fibrillation ( AF ) . - pubmed
METHODS : From HF patients hospitalized in the First Affiliated Hospital of Nanjing Medical University during June 2012 and June 2014 , subjects were recruited based on electrocardiography examination , including 110 patients with AF ( coexisting AF group ) and 105 parallel control patients without AF but with matched age , gender and body mass index ( simple HF group ) . - pubmed
Compared with the patients in simple HF group , the patients in coexisting AF group had a significantly higher Epworth sleepiness scale score , larger cardiothoracic ratio ( 10.1 + -5.8 vs 8.2 + -5.5 , 0.63 + -0.08 vs 0.57 + -0.07 ; both P<0.05 ) , and shorter 6 - minute walk distance [ ( 305 + -70 ) vs ( 335 + -69 ) m , P<0.05 ] . - pubmed
CONCLUSION : HF patients with AF have a higher frequency of SAS , more severe daytime sleepiness and poorer physical activity than matched simple HF patients without AF . - pubmed
Histopathological thrombus analysis in patients with stent thrombosis : what are the missing pieces in the puzzle ? - pubmed
We aim to measure the incidence of trastuzumab - related cardiotoxicity in patients with early and metastatic breast cancer in the south of Brazil . - pubmed
Results Trastuzumab - related cardiotoxicity was observed in 58 patients ( 53.2 % ) . - pubmed
Emergency and hospitalization admissions were necessary in seven and three patients , respectively , due to symptoms of heart failure . - pubmed
One patient died in consequence of trastuzumab - related cardiotoxicity . - pubmed
A 23 - year - old male patient presented with headache and vomiting for 3 - 4 days and giddiness for 4 - 5 days . - pubmed
Endoscopic excision of the lesion was done , and the patient had relief of a headache and vomiting immediately after the procedure . - pubmed
BACKGROUND : Patients with non - muscle - invasive bladder cancer ( NMIBC ) belonging to the intermediate - risk group should be treated with intravesical instillations to prevent recurrence and progression . - pubmed
There is increasing use of percutaneous interventional techniques for occlusion of aortic pseudoaneurysms in patients who are considered unsuitable for surgery . - pubmed
METHODS AND RESULTS : Retrospective evaluation of the catheter laboratory database was performed at our center and anonymized data was obtained for patients who had nonstent endovascular treatment of APAs . - pubmed
Seven patients had the combined occlusion and embolization technique , only 1/7 ( 14.3 % ) died from complications related to APAs . - pubmed
Methods and results of this study were aimed to inform the implementation of risk - based interventions to better prevent and control TB at the wildlife - livestock interface , a necessary step for the successful eradication of TB in cattle in Spain . - pubmed
CONCLUSIONS AND RELEVANCE : There was a significant improvement in depressive symptoms at 6 months after treatment for patients receiving cochlear implants and hearing aids ; this improvement persisted to 12 months for those who received cochlear implants . - pubmed
A trial , involving 26 client - owned dogs with lameness due to cranial cruciate ligament failure , was started . - pubmed
Modified Maquet procedure appears to be an effective treatment for lameness due to failure of the cranial cruciate ligament in dogs . - pubmed
African green monkeys ( AGM ) and sooty mangabeys ( SM ) are well - studied natural hosts of simian immunodeficiency virus ( SIV ) that do not progress to AIDS when infected with their species - specific viruses . - pubmed
Costs of providing infusion therapy for patients with inflammatory bowel disease in a hospital - based infusion center setting . - pubmed
Recent research suggests transcranial direct current stimulation ( tDCS ) targeting the dorsolateral prefrontal cortex can potentiate cognitive improvements in healthy individuals and those with psychiatric conditions , such as schizophrenia . - pubmed
Traumatic injury to the foot and ankle can result in long - term disability , which may have substantial negative implications on a patient 's functional outcomes and quality of life . - pubmed
Mite allergoids coupled to nonoxidized mannan from Saccharomyces cerevisae efficiently target canine dendritic cells for novel allergy immunotherapy in veterinary medicine . - pubmed
farinae allergens coupled to nonoxidized mannan is a novel allergen preparation suitable for canine allergy immunotherapy targeting dendritic cells . - pubmed
By means of a double crossover recombination strategy , successfully used for the first time in bifidobacteria , Balat_1410 in the type strain B. - pubmed
Remarkably , qualitative and quantitative fluorescence analyses demonstrated that the ropy strain displays a lower capability to adhere to human intestinal epithelial cells . - pubmed
In humans this increases the vulnerability to develop mental illnesses while in the rodent brain early life stress ( ELS ) abnormalities are associated with changes in synaptic plasticity , excitability and microstructure . - pubmed
Detailed information on the effects of ELS on rodent brain structural integrity at large and connectivity within the brain is currently lacking ; this information is highly relevant for understanding the mechanism by which early life stress predisposes to mental illnesses . - pubmed
The aim of this study was to ascertain the response of muscle progenitor cells following thermal injury in mice and to enlighten the cellular cascades that contribute to the muscle wasting . - pubmed
METHODS : C57BL/6 mice received a 20 % total body surface area ( TBSA ) thermal injury . - pubmed
Methods : A total of 20 patients with trichlorethylene - induced dermatitis who were admitted and treated from January 2014 to October 2016 were enrolled as case group , and 20 persons who underwent physical examination from January to October , 2016 were enrolled as control group . - pubmed
Percutaneous cryoablation of breast tumours in patients with stable metastatic breast cancer : safety , feasibility and efficacy . - pubmed
PURPOSE : To evaluate safety , feasibility and efficacy of percutaneous cryoablation of breast tumours in patients with clinically stable metastatic breast cancer , and to compare the findings with reports on alternative procedures , namely surgery and local radiotherapy . - pubmed
METHODS : 17 female patients ( average age of 54.8 years + - 10.8 ; range 37 - 72 ) with primary breast tumour not surgically treated because of metastatic disease were included . - pubmed
In 15 patients , we obtained a complete regression of the primary breast lesion without recurrence during the follow - up period . - pubmed
Two patients with lesions measured at 40 and 45 mm had recurrence in follow up period . - pubmed
Advances in knowledge : Therapies are limited for these symptomatic patients at metastatic state of primary breast tumour . - pubmed
Approval was based on results from an international , multicenter , multicohort , noncomparative , open - label trial , study BRF113928 , which sequentially enrolled 93 patients who had received previous systemic treatment for advanced NSCLC ( Cohort B , n = 57 ) or were treatment - naive ( Cohort C , n = 36 ) . - pubmed
OBJECTIVE : To analyze the clinical features of 6 patients with imported schistosomiasis mansoni , including the epidemic history , clinical manifestations , laboratory tests and therapeutic effect , so as to provide references for improving the levels of diagnosis and treatment of physicians . - pubmed
METHODS : The clinical data of 6 patients with imported schistosomiasis mansoni from January 2009 to July 2016 were collected and analyzed . - pubmed
RESULTS : All the 6 imported patients with schistosomiasis mansoni had a clear history of cercarial infested water exposure . - pubmed
Hydroperitoneum and splenomegaly signs were discovered by abdominal ultrasonography in 16.6 % ( 1/6 ) of the patients . - pubmed
Colitis was found in all the patients , and 66.6 % ( 4/6 ) of the patients were combined with multiple colonic ulcers by the electronic colonoscopy examination . - pubmed
Chronic inflammation and eosinophil infiltration were found in all the patients by rectum pathology . - pubmed
No mixture related adverse events ( nausea , vomiting , pruritus , sedation , respiratory depression ) or those related to electrocardiographic parameters ( arrhythmias and asystole ) were reported in any patients . - pubmed
The transport of these metallodrugs by four different hepatopancreatic cell types ( embryonic ( E ) , resorptive ( R ) , fibrillar ( F ) , and blister ( B ) ) of U. - pubmed
We investigated the effectiveness of shear wave elastography ( SWE ) in patients with lower extremity superficial venous insufficiency ( VI ) . - pubmed
CONCLUSIONS : In a longitudinal study of patients with CKD who subsequently initiated dialysis therapy , LVEF and LVESV worsened and were significantly associated with greater risk for postdialysis mortality . - pubmed
After a median follow - up of 52 months , a report from the Swedish Multicenter Cohort Study presented a worse cancer - specific and event - free survival for patients with micrometastases than node - negative individuals , but could not demonstrate a significant difference in overall survival ( OS ) . - pubmed
METHODS : Between September 2000 and January 2004 , 3355 breast cancer patients were included in a prospective cohort . - pubmed
Patients with micrometastases received less often chemotherapy than those with macrometastases ( 24.4 vs. 53.9 % ) . - pubmed
This study demonstrates a similar survival for patients with micrometastases and those with macrometastases , possibly due to systemic undertreatment . - pubmed
One important hallmark of autoimmune diseases is the detection of autoantibodies in patient sera . - pubmed
The muscles of IMNM patients are characterized by necrosis , atrophy and regenerating fibres with sparse inflammatory infiltrates . - pubmed
We present a 64 - year - old patient who developed agranulocytosis after starting ATD to treat relapsed Graves ' disease . - pubmed
With the growing knowledge on the molecular mechanisms involved in the pathophysiology of ED , a number of therapeutic gene strategies have been extensively tested and proven to be effective in many animal models . - pubmed
Our results suggest that high - risk patients who have chronic GVHD or who receive glucocorticoid therapy may require reduced dose of glucocorticoid and long - term physical support to recover physical function after transplantation . - pubmed
BACKGROUND Resveratrol , a polyphenol found on the surface of red fruits , is able to suppress many kinds of malignancies . - pubmed
Pre - clinical development of Listeria - based nanovaccines as immunotherapies for solid tumours : insights from melanoma . - pubmed
Studies using mouse models of subcutaneous melanoma indicated that GNP - LLO91 - 99 nanovaccines recruite and modulate dendritic cell ( DC ) function within the tumour , alter tumour immunotolerance inducing melanoma - specific cytotoxic T cells , cause complete remission and improve survival . - pubmed
Studies on monocyte - derived DCs from patients with stage IA , IB or IIIB melanoma confirmed the ability of GNP - LLO91 - 99 nanovaccines to complement the action of checkpoint inhibitors , by not only reducing the expression of cell - death markers on DCs , but also potentiating DC antigen - presentation . - pubmed
The aim of this study was to investigate whether oral contraceptives ( OC ) use changes the lipoprotein profile associated with disability in patients with multiple sclerosis . - pubmed
Methods : Clinical data was collected from 133 relapsing - remitting multiple sclerosis ( RRMS ) women with a mean of 6.5 years of disease duration and prior to the start of disease - modifying therapies . - pubmed
Conclusions : Serum lipid profile is associated with protective effects of OC use on disability of RRMS patients . - pubmed
METHODS : A total of 811 patients with upper gastrointestinal symptoms and histopathological diagnosis of chronic gastritis were enrolled in the study . - pubmed
Comment on the article : " Microvascular effects of intravenous esmolol in patients with normal cardiac function undergoing postoperative atrial fibrillation : a prospective pilot study in cardiothoracic surgery " . - pubmed
Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol - induced hepatotoxicity in Wistar rats . - pubmed
Deficiency of programmed cell death 4 affects the balance of T cell subsets in hyperlipidemic mice . - pubmed
BACKGROUND : Depressive symptoms and impaired physical functioning are prevalent among older adults . - pubmed
METHODS : This study was a randomized placebo - controlled trial with 155 participants aged 60 - 80 y who had clinically relevant depressive symptoms , & gt;=1 functional limitations , and serum 25 - hydroxyvitamin D [ 25 ( OH ) D ] concentrations of 15 - 50/70 nmol / L ( depending on season ) . - pubmed
CONCLUSIONS : Supplementation with 1200 IU / d vitamin D for 12 mo had no effect on depressive symptoms and physical functioning in older persons with relatively low vitamin D status , clinically relevant depressive symptoms , and poor physical functioning . - pubmed
Knee arthroplasty should always be cemented in patients with known osteoporosis . - pubmed
Deregulation of microRNA expression has been shown to play an important role in human malignancies . - pubmed
We evaluated ToM in patients with schizophrenia spectrum disorders ( SSDs ) , their healthy first - degree relatives , and controls to test its suitability as an endophenotypic marker . - pubmed
: The sample included 38 stable SSD patients , 80 unaffected first - degree relatives , and 81 controls . - pubmed
EGCG , at a concentration of 10 mg / kg , caused behavioral changes in rats similar to anxiety . - pubmed
Our results suggested that the composition of gut microbiota and anxiety in OVX rats were simultaneously affected by EGCG , and therefore , the two conditions might be strongly related , yet the deeper mechanistic links need further exploration . - pubmed
Triggers and blockers of cirrhotic cardiomyopathy are poorly understood , which might compromise the prognosis of chronic liver disease patients . - pubmed
Ethanol Extract of Caesalpinia decapetala Inhibits Influenza Virus Infection In Vitro and In Vivo . - pubmed
Influenza virus infections can lead to viral pneumonia and acute respiratory distress syndrome in severe cases , causing significant morbidity and mortality and posing a great threat to human health . - pubmed
The animal study revealed that EEC administration reduces the weight loss and improves the survival rate of mice infected with lethal influenza virus . - pubmed
RESULTS : Infection was successfully controlled in 48 of 51 patients ( 94.1 % ) ; of these , 24 knees ( 50.0 % ) required no reoperation subsequent to the index KA , whereas the remaining 24 ( 50.0 % ) patients required a median of 1 additional operation . - pubmed
Nonunion , malunion , or delayed union was noted in 10 patients ( 19.6 % ) . - pubmed
CONCLUSION : Patients undergoing KA for TKA PJI had high rates of infection control and preservation of ambulatory status , with low rates of progression to AKA in our study . - pubmed
Methods : Clinical and serological data of 72 CSU patients ( ie , 18 r - CSU and 54 age and sex matched Or - CSU ) were retrospectively collected and analyzed . - pubmed
All patients were diagnosed with CSU for > = 6 months and treated at the Sheba Medical Center during 2013 - 2018 . - pubmed
Results : Of 289 CSU patients , 18 ( 6 % ) were diagnosed with r - CSU and treated with the " intensified protocol " including omalizumab and cyclosporine - A ( 16p ) , methotrexate ( 1p ) , and azathioprine ( 1p ) . - pubmed
Emerging preclinical evidence does not support broad use of hydroxychloroquine in COVID-19 patients . - pubmed
Adult rats , fed long term with diethylnitrosamine ( DENA , 10 mg / kg / day ) develop liver carcinoma after 90 days of carcinogen administration . - pubmed
[ State of circulation in the limbs of patients with angiodystonic disorders of vibrational origin ] . - pubmed
[ Effectiveness of intraoperative cytological examination of peritoneal washings for patients with pancreatic cancer ] . - pubmed
To confirm the effectiveness of cytological examination of peritoneal washings for detecting invisible micro - peritoneal dissemination in patients with pancreatic cancer , results were analyzed with the survival and the background factors of the patients . - pubmed
Cytological examination of peritoneal washings or ascitic fluid at recto - vesical pouch or pouch of Douglas was performed in 37 patients with primary pancreatic cancer . - pubmed
Two of the 8 patients received resection of the tumor . - pubmed
Other 6 patients without resection developed clinically evident peritoneal carcinomatosis . - pubmed
A high positive rate ( 66.7 % ) of cytological examination of the patients with visible peritoneal dissemination and a high incidence of appearance of peritoneal carcinomatosis in patients with positive cytological results but without visible peritoneal dissemination ( 75.0 % ; positive vs 26.1 % ; negative ) indicate a high reliability of the cytological examination to detect invisible micro - peritoneal dissemination . - pubmed
Estrogen replacement therapy ( ERT ) has been demonstrated to prevent osteoporosis in postmenopausal women ( PMW ) . - pubmed
Reduced concentration of hepatic alpha - tocopherol in patients with alcoholic liver cirrhosis . - pubmed
The concentration of alpha - tocopherol was measured in liver biopsy specimens obtained from 83 patients with alcoholic and non - alcoholic liver diseases . - pubmed
The mean hepatic vitamin E content ( as alpha - tocopherol ) was significantly lower in 23 patients with alcoholic cirrhosis ( 17.6 + /- 12.1 nmol / mg wet weight liver ) , compared with 12 patients with normal liver histology ( 39.2 + /- 29.7 nmol / mg , P less than 0.01 ) . - pubmed
The mean serum concentration of alpha - tocopherol was lower in patients with alcoholic cirrhosis ( 13.9 + /- 7.0 mumol / l ) than in individuals with alcoholic fatty liver ( 21.3 + /- 9.3 mumol / l , P less than 0.01 ) and patients with normal liver histology ( 23.4 + /- 11.6 mumol / l , P less than 0.01 ) . - pubmed
A decreased ratio of serum alpha - tocopherol / total serum lipids was also observed in patients with alcoholic cirrhosis , compared with patients with normal liver histology ( P less than 0.05 ) . - pubmed
Similarly , the primary tumors of patients with skeletal metastasis contained considerably less enzyme activity compared with those of patients surviving without skeletal metastasis . - pubmed
Degree and duration of bronchial hyperreactivity ( BHR ) after environmental tobacco smoke ( ETS ) inhalation was assessed in 31 smoke - sensitive subjects with asthma who exhibited lower airway symptoms on ETS exposure ( group I ) and 39 smoke - sensitive subjects without asthma who manifested only upper airway symptoms on cigarette - smoke exposure ( group II ) . - pubmed
Partial obstruction of the opossum esophagus leads to thickening of the circular muscle , hypertrophy of smooth muscle cells , and diminution of the extracellular space . - pubmed
Each of these chemicals had been reported positive in the Ames test and/or the mouse lymphoma TK+/- mutation assay . - pubmed
This chemical has been shown recently to cause various tumors in rodents . - pubmed
Longitudinal electroretinogram study in a patient with metallosis oculi . - pubmed
Serial electroretinograms were obtained from a patient with visual loss secondary to an intraocular metallic foreign body . - pubmed
An epidemiological study on occupational acute pyrethroid poisoning in cotton farmers . - pubmed
A cross sectional survey on the prevalence of acute pyrethroid poisoning in cotton farmers was conducted in 1987 and 1988 . - pubmed
Properties of macrophages from high- and low - responder strains of mice . - pubmed
Direct diffusion of cis - diamminedichloroplatinum ( II ) in intraperitoneal rat tumors after intraperitoneal chemotherapy : a comparison with systemic chemotherapy . - pubmed
We have developed a rat tumor model in which penetration and distribution of cis - diamminedichloroplatinum ( II ) into intraperitoneal tumors have been studied . - pubmed
Factors affecting the clinical response to treatment with digoxin and two calcium antagonists in patients with atrial fibrillation . - pubmed
Sexual function was studied in 15 males with myotonic dystrophy . - pubmed
Bacteriological effects of anti - Pseudomonas aeruginosa chemotherapy in cystic fibrosis . - pubmed
Strains of Pseudomonas aeruginosa resistant to clinically relevant antibiotics ( beta - lactams , quinolones , aminoglycosides ) were detectable in sputa of cystic fibrosis patients . - pubmed
Ambulant , transcutaneous PCO2 monitoring has been used to show that hyperventilation precedes exacerbation of asthma in a patient . - pubmed
Conduction in the central motor pathways was studied in 9 patients with cerebrovascular disease ( CVD ) , 13 with amyotrophic lateral sclerosis ( ALS ) and 3 with spinal progressive muscular atrophy ( SPMA ) . - pubmed
In patients with CVD , responses to cortical stimulation were unobtainable or delayed in the paretic limb muscles . - pubmed
In patients with ALS the abnormality of central motor conduction had significant correlation with the extensor plantar response . - pubmed
By comparative sonographic and myelographic investigations of 61 patients with lumbar disc herniations and other nerval compressive syndromes , the value of the spinal sonography in the diagnosis of lumbar disc herniation is demonstrated . - pubmed
Clinical features , diagnostic procedure , therapy , course of the disease and prognosis in 6 patients with severe idiopathic chronic cold agglutinin disease are described . - pubmed
In 5 patients the main complaint was cold mediated acrocyanosis . - pubmed
One patient developed a lymphoproliferative disorder 11 years after diagnosis of idiopathic chronic cold agglutinin disease . - pubmed
Fifteen patients with congenital ptosis with a varying amount of levator action were operated on with this technique . - pubmed
A human KB carcinoma cell line and a Chinese hamster ovary cell line selected for crossresistance to multiple chemotherapeutic agents , including most antimitotic drugs , are sensitive to DCBT . - pubmed
Cell - mediated immune responses to influenza virus antigens expressed by vaccinia virus recombinants . - pubmed
These recombinant viruses together with a recombinant expressing the HA from influenza virus A / JAP / 305 / 57 ( H2N2 ) have been used to examine the cytotoxic T lymphocyte ( CTL ) response to these influenza virus antigens . - pubmed
[ Tremor development in dogs caused by stimulation of the dorsal hippocampus ] . - pubmed
The triphasic response of the isolated superior cervical ganglion of the rat to cholinergic stimulants . - pubmed
[ The transforming effect of blood from leukemic patients on a culture of human diploid cells ] . - pubmed
[ Histological study of experimental autolysis of the striated muscle of the guinea pig ] . - pubmed
Grades of atypia in tubular and villous adenomas of the human colon . - pubmed
Of a total of 544 tubular , villous and tubulo - villous adenomas of the human colon which were investigated by light microscopy , six tubular and six villous adenomas were examined under the electron microscope . - pubmed
Twenty - two patients with advanced stage germ cell carcinomas received a combination chemotherapy regimen of cis - platinum , vinblastine , bleomycin and actinomycin D. - pubmed
Only one relapse has occurred among the former group with 82 % alive and disease - free with follow - up of 27 - 50 months , indicating the majority of these patients may be cured . - pubmed
Management of advanced stage germ cell carcinoma can now be considered highly successful although further studies are needed to determine optimal treatment for patients with bulky disease and the role , if any , of maintenance therapy . - pubmed
[ Effect of levamisole on peripheral blood neutrophils in patients with neoplasms ] . - pubmed
The history of a patient with two thoracoabdominal aneurysms and lumbar Pott ' s disease is reported . - pubmed
In the postoperative course the patient experienced acute low back pain . - pubmed
The incidence over 7 days of isotopically - detected calf and popliteal vein thrombosis was determined in a group of 60 diabetic patients admitted to hospital with myocardial infarction , heart failure or stroke , or for abdominal surgery . - pubmed
Metabolic and clinical disturbances in patients with calcium urolithiasis . - pubmed
Human brucellosis in the Negev region of Israel , 1981 . - pubmed
High levels of LA were also found in the pleural fluid of 15 patients with malignancy of pleural cavity . - pubmed
A patient with several episodes of jaundice associated with sulfamethoxazole therapy is described . - pubmed
After an injection of fluorescein , levels of fluorescein in the vitreous humor are reported to be elevated in diabetic patients compared with controls even when there is no retinal pathologic condition discernible by angiography or ophthalmoscopy . - pubmed
An analysis of 245 children with hypertension seen in 3 years in the Southern Railway Hospital , Madras is presented . - pubmed
[ Hypertensive pulmonary vascular disease in children . - pubmed
In the past , in countries where otitis media is usually treated , complications have been rare , because of the good activity of almost all orally administered antibiotics against the most common cause of complications , Streptococcus pneumoniae . - pubmed
A proportion of rats exposed to inescapable tailshock stress displayed a performance deficit , termed learned helplessness , in a subsequent shuttlebox avoidance task . - pubmed
Following an exposure to a milder form of inescapable shock , an increase in norepinephrine output was detected in learned helpless rats , which was significantly greater than nonhelpless , nonprestressed , or control animals . - pubmed
Therefore , the possibility exists that similar neurochemical changes may also be responsible for some of the symptoms of human posttraumatic stress disorder ( PTSD ) , such as the poor coping associated with seemingly mild stress . - pubmed
Acute inflammation in foetal and adult sheep : the response to subcutaneous injection of turpentine and carrageenan . - pubmed
Because of the small number of inflammatory cells found in skin wounds , it has been considered that foetal sheep are incapable of an adequate inflammatory response . - pubmed
Nerve blood flow , reflected by laser Doppler flow measurements , and motor nerve conduction velocity were both significantly less in diabetic than in control animals . - pubmed
Thirty - eight patients ( 16 males and 22 females ) with mediastinal cysts have been treated at the Second Department of Surgery at Okayama University from 1978 to 1989 . - pubmed
Baclofen administration for the treatment of affective disorders in alcoholic patients . - pubmed
Ninety alcoholic patients with the secondary affective disorders ( anxiety , depression ) were divided into four groups . - pubmed
The results of clinical , psychological ( tests of Spielberger , Zung and MMPI ) , and electrophysiological ( superslow omega - potential ) investigations showed that baclofen is an effective drug for affective disturbances in alcoholic patients , with efficacy superior to placebo and equal to diazepam and amitriptyline . - pubmed
The peripheral matabolism of GABA and monoamines do not seem to be related to the development of secondary affective disorders in alcoholic patients . - pubmed
To determine the role of animals as possible sources for human infection with Campylobacter jejuni / coli , 218 human cases of Campylobacter enteritis diagnosed among members of Group Health Cooperative of Puget Sound , King County , Washington , from April 1982 through September 1983 were compared with 526 controls , randomly selected from Group Health Cooperative members . - pubmed
To prove the hypothesis that cardiopulmonary bypass may accelerate the development of acquired immunodeficiency syndrome ( AIDS ) in the human immunodeficiency virus carrier , the clinical course of 40 patients positive for human immunodeficiency virus who underwent cardiac operations between 1986 and 1992 was analyzed , especially in regard to the progression to AIDS . - pubmed
Valve procedures were performed in 38 patients ( 95 % ) , mostly for endocarditis in drug addicts . - pubmed
Four patients ( 12.5 % ) experienced progression to AIDS during the follow - up period . - pubmed
The majority of strains of the main causative agent , Aspergillus fumigatus , produce gliotoxin , a secondary metabolite with demonstrated in vitro immunosuppressive activity . - pubmed
Pretreatment of normally resistant mice with a single injection of a sublethal dose of gliotoxin was sufficient to make them susceptible to infection and subsequent death , after challenge with A. - pubmed
PURPOSE : This report describes a female infant with stage 4 multifocal ganglioneuroblastoma with gastric involvement . - pubmed
PATIENT : The patient had a right cervical tumor , a left posterior mediastinal tumor , bilateral adrenal tumors , and bony and bone marrow metastases . - pubmed
The latter mechanism may have accounted for our patient 's gastric tumor . - pubmed
Patients with multifocal ganglioneuroblastomas warrant meticulous radiographic and surgical evaluation to completely document the full extent of disease , and to ensure appropriate staging and therapy . - pubmed
Effect of six - month treatment with Ukrain on early osteoporosis induced by ovariectomy in rats . - pubmed
A retrospective study was performed to determine whether there is an increased incidence of hyperglycemia in patients not predisposed to hyperglycemia ( n = 102 ) who receive total parenteral nutrition ( TPN ) dextrose in excess of 4 to 5 mg / kg / min . - pubmed
Of the 37 subjects administered dextrose at & gt ; 5 mg / kg / min , 18 exhibited hyperglycemia . - pubmed
OBJECTIVES : Following an outbreak of tuberculosis ( TB ) among health care workers at a public hospital , the study was undertaken to ( a ) locate all exposed patients and administer tuberculin skin tests ( TSTs ) to them , ( b ) provide clinical treatment or prophylaxis to infected patients , and ( c ) ascertain the risk of M. - pubmed
In all , 362 patients ( 72 % ) were lost to follow - up , including many HIV - positive and homeless patients , who are at high risk of developing active TB once infected with M. - pubmed
In the present study we have found a similar synergistic interaction between exifone and ascorbic acid ( vitamin C ) against both chloroquine - susceptible and multidrug - resistant strains of Plasmodium falciparum . - pubmed
Morris water maze deficits in rats following traumatic brain injury : lateral controlled cortical impact . - pubmed
Adult rats were subjected to one of two different levels of cortical injury , mild ( 1 mm ) or moderate ( 2 mm ) deformation , and subsequently tested for their ability to learn ( acquisition ) or remember ( retention ) a spatial task , 7 or 14 days after injury . - pubmed
Results revealed an injury - dependent deficit for experimental animals compared to sham - operated controls . - pubmed
This study was carried out to investigate the immunological status of 50 transfusion - dependent children with beta - thalassaemia , taking into account that lymphocyte characteristics are affected by sex , age and race . - pubmed
RESULTS : The normal Chinese children had higher NK levels than the beta - thalassaemia children . - pubmed
BACKGROUND : The effects of simulated " ischemia " and " reperfusion " were evaluated in cell cultures of human ventricular cardiomyocytes and human saphenous vein endothelial cells . - pubmed
3 - Hydroxybutyrate aids the recovery of the energy state from aglycaemic hypoxia of adult but not neonatal rat brain slices . - pubmed
Gastroesophageal reflux and a comparison of the different antireflux procedures following esophagomyotomy : an experimental study in rabbits . - pubmed
PATIENTS AND METHODS : Thirty - one eyes of 28 consecutive patient who underwent AK for excessive postkeratoplasty astigmatism were studied . - pubmed
Cardiac parasympathetic stimulation via QRS - synchronous low - energy shocks in humans . - pubmed
INTRODUCTION : In patients receiving test shocks to verify lead connections at implantation , we anecdotally have observed postshock delay . - pubmed
Each patient received QRS - synchronous shocks of 0.2 , 0.4 , 0.6 , and 2.0 J in random order . - pubmed
Patients were further randomized to receive either saline or 2.0 mg atropine intravenously , and then given a second sequence of shocks . - pubmed
CONCLUSION : Low - energy shocks delivered during the QRS complex cause postshock cycle length prolongation in man . - pubmed
A total of 103 patients comprising 95 squamous cell carcinomas , 3 adenosquamous cell carcinomas and 5 adenocarcinomas , were studied . - pubmed
The positivity of the patients with abnormal sr - SCC levels for squamous cell carcinoma , adenosquamous cell carcinoma and adenocarcinoma were 87.7 % , 50.0 % and 40.0 % , respectively The 5 - year - survival rates of sr - SCC positive and negative patients were 71.1 % and 100 % , respectively ( P & gt ; 0.1 ) . - pubmed
The positivity of patients with im - CA19 - 9 in squamous cell carcinoma , adenosquamous cell carcinoma , im - CA19 - 9 adenocarcinoma were 29.1 % , 66.6 % , and 100 % , respectively . - pubmed
These results suggested that follow - up of patients by periodical serum examination for these tumor markers is highly useful for the early detection of tumor relapse . - pubmed
These are absorbtion of bacteria and their toxins from peritoneum , phagocytosis , opsonization , activation of the complement and separation of infection in the peritoneal cavity . - pubmed
This phase I study was undertaken to define the maximum tolerated dose , dose - limiting toxicity , and recommended dosage of UFT ( uracil and tegafur ) plus oral calcium folinate ( Orzel ) and vinorelbine ( Navelbine ) in combination treatment of metastatic breast cancer in patients who have received one prior chemotherapy regimen . - pubmed
The effect of butylated hydroxytoluene on selected immune surveillance parameters in rats bearing enzyme - altered hepatic preneoplastic lesions . - pubmed
A lag in time needed to attain maximum calcium release was observed only in the rats with PH compared with those without PH . - pubmed
Further investigations are necessary to determine whether the observed suppression of NK cell activity during EAF induction and growth modulation by BHT is a contributing factor in enhancement of rodent liver neoplasia by this non - genotoxic food antioxidant . - pubmed
Liver scintigraphy is useful for selecting candidates for preoperative transarterial chemoembolization among patients with hepatocellular carcinoma and chronic liver disease . - pubmed
BACKGROUND : The indications for preoperative hepatic transarterial chemoembolization ( TACE ) have not been clarified by recent studies in patients with hepatocellular carcinoma ( HCC ) complicated by chronic liver diseases . - pubmed
PATIENTS AND METHODS : Liver scintigraphy was performed before and several weeks after TACE in 64 patients with HCC complicated by chronic hepatitis or cirrhosis . - pubmed
Three major postoperative complications occurred in patients with LHL15 & gt ; or = 0.91 , and no major complications occurred in patients with LHL15 & lt;0.91 . - pubmed
CONCLUSIONS : The results suggest that preoperative TACE should be performed in HCC patients only when LHL15 is less than 0.91 , and that preoperative TACE is not an appropriate treatment for patients with LHL15 & gt ; or = 0.91 when HCC is resectable . - pubmed
The total number of complications was 0.24 episodes per patient per year at risk and the rate of thrombosis 0.1 . - pubmed
Patients with glomerulonephritis had the best function rates for their VA , the median exceeding the duration of the study , whereas in half of the diabetic patients it was less than 1 year . - pubmed
Three patients in this group had postoperative stroke . - pubmed
Total 10 patients ( 2.1 % ) sustained neurological complications . - pubmed
We report on a 75 - year - old female patient who developed several thermal keratoses and squamous cell carcinomas at the site of erythema ab igne caused by chronic heat exposure over several years . - pubmed
Larval growth of Diaprepes abbreviatus ( Coleoptera : Curculionidae ) and resulting root injury to three citrus varieties in two soil types . - pubmed
Larval growth and intraspecific competition of Diaprepes abbreviatus ( L. ) larvae and consequent root injury in container - grown citrus in the greenhouse were evaluated . - pubmed
Although not statistically significant , root injury developed slightly slower on Swingle citrumelo compared with Carrizo and Cleopatra rootstocks , but damage was comparable by 79 d. Little or no difference in consumptive benefit to the larvae was found between the rootstocks . - pubmed
Thallium-201 myocardial SPET in patients with collagen disease . - pubmed
We analysed stress 201Tl myocardial single photon emission tomography ( SPET ) in collagen disease patients to evaluate abnormal uptake patterns and their clinical significance in the assessment of the cardiac status of these patients . - pubmed
Twenty - two collagen disease patients ( 13 with progressive systemic sclerosis ( PSS ) and nine with systemic lupus erythematosus ( SLE ) ) were examined by 201Tl myocardial SPET with exercise ( n = 9 ) or dipyridamole stress ( n = 13 ) . - pubmed
Patients were divided into two groups : those with cardiac abnormalities on conventional testing ( Group A , n = 10 ) and those without ( Group B , n = 12 ) . - pubmed
High - risk groups for hepatitis C virus infection included recipients of blood transfusion of which the blood donors were not screened for anti - HCV , intravenous drug abusers , hemophiliacs , and patients who have received hemodialysis . - pubmed
Hepatitis C virus was the most common cause of chronic hepatitis , cirrhosis , and hepatocellular carcinoma in Western countries and in Japan , where hepatitis B virus is not endemic . - pubmed
However , the relapse rate was high and only 20 % to 25 % of patients sustained response 1 year after discontinuing therapy . - pubmed
Role of budesonide inhalation suspension in children with asthma . - pubmed
OBJECTIVE : To evaluate the role of budesonide inhalation suspension ( BIS ) in the treatment of children with asthma . - pubmed
DATA SYNTHESIS : Asthma is a chronic inflammatory disease that affects approximately 4.8 million children in the US . - pubmed
As the first nebulized corticosteroid , BIS offers an important treatment option for children with persistent asthma . - pubmed
CONCLUSIONS : BIS is effective in reducing symptoms and improving lung function in children with asthma . - pubmed
It should be used in children ages 1 - 8 years with moderate to severe persistent asthma who are unable to effectively use a metered - dose inhaler with or without a spacer or a dry - powder inhaler . - pubmed
Diet enriched with omega-3 fatty acids alleviates convulsion symptoms in epilepsy patients . - pubmed
PURPOSE : We examined whether a dietary supplement containing omega-3 polyunsaturated fatty acids ( n-3 PUFAs ) can alleviate and/or reduce the frequency of epileptic seizures in patients with central nervous system ( CNS ) diseases treated with anticonvulsive drugs ( ACDs ) . - pubmed
METHODS : The records of 27 patients ( 30 eyes ) having undergone orbital decompression of one wall , two walls and three walls for severe thyroid orbitopathy were analyzed for changes in visual acuity , visual field or pattern visual evoked potential , movement and reduction in proptosis . - pubmed
CONCLUSION : Orbital decompression is effective in improving vision in most patients with severe thyroid associated ophthalmopathy , and the proptosis can be effectively improved . - pubmed
Toward a better understanding of light - induced photoreceptor damage , the crystallin content of rat retina was examined following intense light exposure . - pubmed
Repetitive R(int ) measurements were performed in 125 healthy children and 107 asthmatic children ( age range 0.8 - 16.8 years ) . - pubmed
The absence of effect of cortisone therapy upon plasma lipid levels in patients with rheumatoid arthritis . - pubmed
Valid and reliable measurements of muscle impairment are needed to assess therapeutic efficacy in patients with generalized myasthenia gravis . - pubmed
A Pugh score of 8 adequately selects patients with parenchymal cirrhosis for liver transplantation . - pubmed
The aim of our study was to develop simple and highly effective scores to estimate prognosis at 1 year for patients with parenchymal cirrhosis and to define the optimum time for liver transplantation with the same degree of accuracy as the prognosis estimation for primary biliary cirrhosis . - pubmed
The prognostic value of 19 variables was studied retrospectively in 91 patients with parenchymal cirrhosis using multivariate analysis and logistic regression . - pubmed
The prognostic value of a Pugh score & lt ; or = 8 or & gt ; 8 was confirmed in a prospective study of 145 cirrhotic patients with 78 % correct prediction . - pubmed
During this period , 21 patients with parenchymal cirrhosis received transplants with a preoperative Pugh score of 9.5 + /- 2.0 ( mean + /- SEM ) and 60 % 1- and 2 - year survival . - pubmed
Although successful and persistent colonization of the gastric mucosa depends on the ability to respond to changing environmental conditions and co - ordinate the expression of virulence factors during the course of infection , Helicobacter pylori possesses relatively few transcriptional regulators . - pubmed
STUDY DESIGN : Thirteen patients underwent intraoperative RF to treat tumors closer than 6 mm to a central bile duct . - pubmed
Twelve patients ( 92.3 % ) did not present any biliary stenosis . - pubmed
In one patient ( 7.7 % ) biliary stenosis was detected 6 months after RF . - pubmed
The patient was cirrhotic but did not require any treatment . - pubmed
One of the 13 patients had a local recurrence . - pubmed
In patients with RCC dielectric permittivity of tumor tissue was 1.43 + /- 0.39 times greater than that of surrounding normal parenchyma ( p & lt ; 0.001 ) . - pubmed
Modified mutation method for screening low citrinin - producing strains of Monascus purpureus on rice culture . - pubmed
Monascus purpureus NTU 601 is a strain that produces monacolin K , gamma - aminobutyric acid ( GABA ) , and citrinin under solid culture conditions . - pubmed
Because citrinin is a mycotoxin and possesses nephrotoxic and hepatoxic effects , it has a negative impact on the acceptance of red mold rice by people . - pubmed
In this research , a simple and quick selection method for mutant strains with low citrinin production was designed based on the fact that citrinin possesses antibacterial activity for Bacillus subtilis and will form an inhibition zone around the colony of the Monascus strain . - pubmed
The mutant strain M. - pubmed
The studies using an immunohistological technique revealed that overexpression of oxidative stress - related substance such as HNE was observed in the liver of primary biliary cirrhosis patients . - pubmed
Four patients in V - P group , 7 in procaine group , and 19 in control group were shown to develop ALI . - pubmed
Two patients were complicated with acute renal failure in V - P group , 2 in procaine group , and 5 in control group . - pubmed
In a large , diverse cohort of human immunodeficiency virus ( HIV )- infected persons receiving routine care , the proportion of eligible persons who discontinued primary prophylaxis against Mycobacterium avium complex ( MAC ) infection , according to guidelines of the US Public Health Service and the Infectious Diseases Society of America , increased from 16.7 % ( in 1996 ) to 84.9 % ( in 2002 ) . - pubmed
Blood specimens were collected from all patients with suspect ' Alkhumra ' virus ( ALKV ) infection and tested for ALKV , RVF , CCHF , dengue , and West Nile encephalitis . - pubmed
The disease seemed to be transmitted from sheep or goat to humans by the mosquito bites or direct contact with these animals . - pubmed
Exercise intolerance is one of the most common symptoms in patients with mitochondrial myopathies ( MM ) . - pubmed
Fewer patients with MM display overt muscle atrophy and weakness even in the absence of a peripheral neuropathy . - pubmed
METHODS : Twenty - two wide - necked , large or giant aneurysms of the internal carotid artery ( ICA ) were treated in 22 patients with Onyx HD 500 ( 15 ophthalmic , 1 clinoid , and 6 cavernous aneurysms ) . - pubmed
Sixteen patients were asymptomatic , and mass effect of the aneuryms caused cranial nerve palsy in 6 . - pubmed
Clinical follow - up demonstrated a transient ischemic attack in 1 patient ; 2 with cranial nerve palsy were unchanged , and 2 showed improved symptoms compared with the findings before treatment . - pubmed
Patients with proven peptic ulcer haemorrhage at endoscopy or operation were included in the study ; those with bleeding under defined severe stress conditions were excluded . - pubmed
We report a patient with an initial diagnosis of Lyme - associated pseudotumor cerebri who developed cerebrospinal fluid pleocytosis consistent with Lyme meningitis . - pubmed
On the other hand , the strain was less susceptible to ischemic injury , and the number of surviving retinal neurons was significantly increased compared with that in wild - type mice . - pubmed
Secondary drowning in a patient with epilepsy . - pubmed
In the current study , we assessed the sensitivity of the combined assay of these three markers in the detection of human bladder transitional cell carcinoma . - pubmed
METHODS : Voided urine samples of 100 patients with bladder transitional cell carcinoma were obtained and each sample was aliquoted for the various assay . - pubmed
HIV prevalence was 1.3 % , overall , 4.1 % in FBDs and 0.1 % in non - FBDs in the community . - pubmed
Amongst the subgroup of FBDs , HIV prevalence was 1.5 % for whole blood only , 21.6 % for plasma only and 8.8 % for both . - pubmed
BACKGROUND : Anger can precipitate ventricular arrhythmias in patients with implantable cardioverter - defibrillators ( ICDs ) . - pubmed
METHODS : At the time of shock , patients with ICDs recorded levels of defined mood states preceding the shock in a diary . - pubmed
The EGMs from 56 appropriate shocks in 24 patients ( 18 male , mean age 66 years , 74 % with coronary artery disease ) were reviewed and analyzed for morphology , mechanism of initiation ( sudden onset vs. premature ventricular contraction [ PVC ] ) , pause dependence , and other characteristics . - pubmed
Infection did not affect the distribution of overwintering larvae in a white spruce canopy . - pubmed
PURPOSE : To report 8 patients with misdiagnosis of MemoryLens intraocular lens ( IOL ) late postoperative calcification and the resulting potentially avoidable procedures leading to secondary complications . - pubmed
Half of the patients were initially diagnosed as having posterior capsular opacification and underwent neodymium : yttrium - aluminum - garnet laser capsulotomy . - pubmed
Six of the 8 patients underwent subsequent lens exchanges , with 3 of them having postexchange complications including endophthalmitis , cystoid macular edema , and retinal detachment . - pubmed
Because the drug is among the most frequently prescribed agents in the US , more controlled studies are required to determine the prevalence of kidney stone disease among TPM users , and the optimal approach to prevent and treat nephrolithiasis in these individuals . - pubmed
Trace elements in cerebrospinal fluid and blood from patients with a rare progressive central and peripheral demyelinating disease . - pubmed
This prospective study was conducted on 52 HIV - positive patients with suspected tuberculosis who were referred to our tertiary care hospital in New Delhi . - pubmed
Twenty - seven HIV - negative but suspected tuberculosis patients were also included for comparison . - pubmed
Of the 16 isolates from blood , 13 were diagnosed as Mycobacterium tuberculosis and one each were identified as M. - pubmed
kansasii , and a mixed infection of M. tuberculosis and M. - pubmed
181 participants were included in this analysis , 72 ( 40 % ) had moderate to severe DD . - pubmed
Cross - sectional studies of men undergoing long - term ( & gt ; or = 12 months ) ADT reveal higher prevalence of diabetes and metabolic syndrome compared with controls . - pubmed
Enteropathogenic Escherichia Coli ( EPEC ) in Infants ' and Travelers ' Diarrhea . - pubmed
Neutralisation of the in vitro neurotoxic effects of taipan venom was determined using a chick biventer cervicis nerve - muscle preparation . - pubmed
All expired taipan / polyvalent antivenom prevented in vitro neurotoxicity at concentrations consistent with antivenom treatment . - pubmed
A mutant of the murine leukemia retrovirus MoMuLV - TB , called ts1 , causes this syndrome in susceptible strains of mice . - pubmed
The Arctic Sun Temperature Management System was used for heating and the patient was warmed to 36.5 degrees C over 6 h. She was extubated after 48 h and transferred to a psychiatric ward two days later . - pubmed
Inhomogeneous sodium accumulation in the ischemic core in rat focal cerebral ischemia by 23Na MRI . - pubmed
BACKGROUND AND OBJECTIVES : By studying cardiometabolic risk factors in children born after maternal biliopancreatic diversion bariatric surgery ( AMS ) compared with those in children born before maternal surgery ( BMS ) , we tested the hypothesis that significant maternal weight loss may modify obesity - related factors transmitted via the intrauterine environment . - pubmed
DESIGN : Anthropometry and fasting blood levels were studied in 49 mothers who had lost 36 + /- 1.8 % body weight sustained for 12 + /- 0.8 yr and their 111 children ( 54 BMS and 57 AMS ) aged 2.5 - 26 yr . - pubmed
RESULTS : AMS children had lower birth weight ( 2.9 + /- 0.1 AMS vs. 3.3 + /- 0.1 kg BMS , P = 0.003 ) associated with a reduced prevalence of macrosomia ( 1.8 AMS vs. 14.8 % BMS , P = 0.03 ) with no difference in underweight . - pubmed
Also cyclosporine can achieve good results while sparing steroids , particularly in patients with persistently elevated proteinuria . - pubmed
These newer strategies may result in fewer adverse effects , better quality of life and better survival for patients with proliferative lupus nephritis . - pubmed
Twenty and one patients developed AF . - pubmed
Patients who developed AF were older but their left ventricular ejection fraction was not different with patients without AF . - pubmed
The ICU stay was higher in patients with AF . - pubmed
Evaluation of the antihypertensive effect of L - arginine supplementation in patients with mild hypertension assessed with ambulatory blood pressure monitoring . - pubmed
The aim of this study was to evaluate the anti - hypertensive efficacy and safety profile of L - arginine during four weeks of oral supplementation to healthy subjects and patients diagnosed with primary mild hypertension . - pubmed
Ambulatory blood pressure monitoring ( ABPM ) was used to allot patients to either a healthy control group ( 19 subjects ) or the hypertensive treatment group ( 35 patients ) . - pubmed
RESULTS : Blood pressure ( both systolic and diastolic ) by ABPM showed statistically significant lowering after 4 weeks of L - arginine supplementation only in the subgroup of patients treated with 12 g of L - arginine daily , with a stronger hypotensive effect observed during the day . - pubmed
METHODS : In this double - blind randomized study , 24 healthy subjects were assigned to receive either an influenza vaccine ( n = 15 ) as a model to generate a systemic inflammatory response or a sham vaccine ( n = 9 ) . - pubmed
The most common symptom was dysphagia , severe in 50 patients ( 40.6 % ) and moderate in 73 ( 59.4 % ) , with a mean dysphagia score of 2.3 ( range 0 - 4 ) . - pubmed
RESULTS : Good results were obtained in 82 patients ( 66.7 % ) , and the improvement of symptoms in 24 ( 19.5 % ) , data confirmed by pre versus postoperative dysphagia mean score ( 2.3 vs 0.4 ) and by regurgitation score ( 0.8 vs 0.2 ) . - pubmed
CONCLUSION : Nowadays esophago - diverticulostomy according to Collard , based on our results and on the literature data , represent the most effective and safe technique for the patients with Zenker ' s diverticulum , with low rate of morbidity and mortality compared to the others surgical on endoscopic procedures . - pubmed
Wide gap arthroplasty if followed by vigorous physiotherapy may be sufficient in treating TMJ ankylosis and prevent recurrence in adults . - pubmed
Elevated cortical glutamate in young people at increased familial risk of depression . - pubmed
The authors made an analysis of the results of treatment of 924 patients with non - small cell lung cancer , operated in the volume of pneumonectomy during 1990 - 2007 years and developed a method of complete suturing the mediastinum wound in order to isolate the bronchus stump from the free pleural cavity and prevention of the development of a bronchopleural fistula . - pubmed
Effects of hyperbaric oxygenation on oxidative stress in acute transient focal cerebral ischemic rats . - pubmed
Rats were assigned to control or HBO group after brain ischemia . - pubmed
In order to examine the role of glutathione after HBO treatment , another group of brain ischemic rats were included to receive the glutathione synthesis inhibitor and HBO treatment . - pubmed
The growing amount of literature about G - quadruplex DNA clearly demonstrates that such a structure is no longer viewed as just a biophysical strangeness but it is instead being considered as an important target for the treatment of various human disorders such as cancers or venous thrombosis . - pubmed
Mechanisms of esophago - pharyngeal acid regurgitation in human subjects . - pubmed
Feasibility of sentinel lymph node biopsy in breast cancer patients with initial axillary lymph node metastasis after primary systemic therapy . - pubmed
This strategy , however , does not eliminate unnecessary ALND in patients with complete remission of axillary metastases . - pubmed
In patients with successful lymphatic mapping , 70.7 % of patients had residual axillary metastases . - pubmed
METHODS : The Covered Versus Balloon Expandable Stent Trial ( COBEST ) , a prospective , multicenter , randomized controlled trial , was performed involving 168 iliac arteries in 125 patients with severe aortoiliac occlusive disease who were randomly assigned to receive a covered balloon - expandable stent or bare - metal stent . - pubmed
Patient demographic data , clinical signs and symptoms , TransAtlantic Inter - Society Consensus ( TASC ) classification , and preprocedure and postprocedure ankle - brachial index measurements were recorded . - pubmed
, impairment affecting the ability to perform everyday activities ) associated with its therapy in pediatric epilepsy , we retrospectively reviewed medical records of 156 patients receiving vigabatrin at Cincinnati Children 's Medical Center from 1998 - 2010 . - pubmed
To evaluate visual impairment ( n = 63 ) , we reviewed serial ophthalmologic evaluations at baseline and during treatment for patients in whom they were clinically indicated . - pubmed
BACKGROUND AND OBJECTIVES : Previous studies have demonstrated that some individuals suffering from obsessive - compulsive disorder ( OCD ) are impaired in verbal memory performance . - pubmed
METHODS : Verbal memory performance of 36 participants with OCD , 36 individuals with major depression disorder ( MDD ) and 36 healthy controls was assessed with the California Verbal Learning Test under three different experimental conditions : ( 1 ) single - task condition , ( 2 ) while simultaneously focusing on their thoughts ( CSC condition ) , ( 3 ) while simultaneously focusing on external stimuli ( dual - task condition ) . - pubmed
Three weeks postoperatively , the patient presented with limbal ischemia , recipient bed melt , and wound dehiscence corresponding to the area of bevacizumab injection . - pubmed
CONCLUSIONS : Multiple sclerosis should be considered in the differential diagnosis of patients who present with isolated cranial nerve palsies . - pubmed
( 18 ) F - FDG is sensitive but has the limitation of giving false positive results in patients with bone prosthesis , even if there is no infection or mobilisation . - pubmed
Sonographic appearance of synovial crystal deposits in 2 patients with gout . - pubmed
METHODS : Six cases of isolated median neuropathy as the first sign of leprosy were selected from patients with an exclusively neurological complaint as the initial symptom . - pubmed
The patients , evaluated at the National Leprosy Reference Center in Rio de Janeiro , Brazil , followed routine and specialized procedures . - pubmed
RESULTS : Three of the patients had pure neural leprosy , and 3 had skin lesions . - pubmed
CONCLUSION : In addition to reconstructive surgery , psychiatric evaluation and intervention would be of benefit in the management of cleft lip patients . - pubmed
Main categories of findings include : nutrition - related effects ( including general malnutrition and mortality , micronutrient malnutrition , and anti - nutrient consumption ) ; water - related disease ( including E coli , cholera and algal bloom ) ; airborne and dust - related disease ( including silo gas exposure and coccidioidomycosis ) ; vector borne disease ( including malaria , dengue and West Nile Virus ) ; mental health effects ( including distress and other emotional consequences ) ; and other health effects ( including wildfire , effects of migration , and damage to infrastructure ) . - pubmed
We established a rat model of hepatic fibrosis . - pubmed
A 37 - year - old man with a recurrent large scrotal mass after two surgeries , suffering with small urinary symptoms as a dysuria and nocturia , was examined before the third surgery on an outpatient basis . - pubmed
The patient 's serum creatinine markedly improved , also hernia and ureterohydronephrosis was repaired with normally moisten without residual urine ( Fig . - pubmed
CONCLUSIONS : Skip N2 metastasis is common in patients with c - stage IA NSCLC with high serum SLX , and lobectomy with complete dissection of hilar and mediastinal lymph nodes should remain the standard surgical procedure for these cases . - pubmed
Reducing lung cancer and other tobacco - related cancers in Europe : smoking cessation is the key . - pubmed
METHOD : Ninety - three patients with migraine and depressive symptoms - being evaluated for a larger project examining the impact of a behavioral intervention on depression in patients with migraine - completed measures of depression , disability , pain acceptance , and values - based action . - pubmed
RESULTS : Twenty - five patients with twenty - six fractures were available for follow - up with a minimum required follow - up of twelve months . - pubmed
Vitamin D concentrations and disease activity in Moroccan children with juvenile idiopathic arthritis . - pubmed
The aim of this study was to assess the relationship between hypovitaminosis D and disease activity in Moroccan children with juvenile idiopathic arthritis ( JIA ) . - pubmed
METHODS : In this cross - sectional study , forty children with JIA were included , all having been diagnosed according to the classification criteria of International League of Associations for Rheumatology ( ILAR ) . - pubmed
The supplement was 90 % DM and contained ( as - fed basis ) 47 % corn gluten feed , 47 % soybean hulls , 2 % feed grade limestone , and 4 % molasses . - pubmed
Duration - dependence of the effect of treadmill exercise on hyperactivity in attention deficit hyperactivity disorder rats . - pubmed
Spontaneously hypertensive rats were used for the ADHD rats and Wistar - Kyoto rats were used for the control rats . - pubmed
The present study suggests that treadmill exercise for 30 min once a day is the most effective therapeutic intervention for ADHD patients . - pubmed
Preoperative predictors of ambulation ability at different time points after total hip arthroplasty in patients with osteoarthritis . - pubmed
Forty - eight women with unilateral THA were measured for hip extensor , hip abductor , and knee extensor muscle strength in both legs ; hip pain ( visual analog scale , VAS ) ; and the Timed Up and Go ( TUG ) test pre- and postoperatively . - pubmed
Rates of single infections were 186/341 ( 54.5 % ) , 93/341 ( 27.3 % ) , and 3 / 341 ( 0.9 % ) , for PRSV , PLDMV , and PapMV , respectively ; 59/341 ( 17.3 % ) of the samples were co - infected with PRSV and PLDMV , which is the first time being reported in Hainan Island . - pubmed
Intensive training of motor function and functional skills among young children with cerebral palsy : a systematic review and meta - analysis . - pubmed
Therefore , the objective of this systematic review was to describe and categorise intensive motor function and functional skills training among young children with CP , to summarise the effects of these interventions , and to examine characteristics that may contribute to explain the variations in these effects . - pubmed
Multi - antigen print immunoassay ( MAPIA)-based evaluation of novel recombinant Leishmania infantum antigens for the serodiagnosis of canine visceral leishmaniasis . - pubmed
BACKGROUND : Domestic dogs are the principal reservoir hosts of Leishmania infantum in regions where visceral leishmaniasis ( VL ) is endemic . - pubmed
Our findings showed that the canine immune response to antigen differs between dogs and depends on infection status . - pubmed
Sigmoid colon diverticulum perforated by a chicken bone . - pubmed
The present study was aimed at isolating R - phycocyanin ( RPC ) from Porphyra haitanensis and determining the anti - allergy potential of RPC in antigen - sensitized mice and mast cells . - pubmed
The most abundant species identified were HAdV - F ( average 89.6 % ) and -A ( average 19.6 % ) , which are associated with intestine infections . - pubmed
Chronic stress promotes oral cancer growth and angiogenesis with increased circulating catecholamine and glucocorticoid levels in a mouse model . - pubmed
MATERIALS AND METHODS : We implanted human oral cancer cell line CAL 27 in nude mice to investigate the effects of chronic stress on tumor growth , and designed a physical restraint system to create an experimentally stressed animal model , in which periodic immobilization induced characteristic chronic stress . - pubmed
Tumor burdened animal were randomly assigned into four groups : ( a ) control group , ( b ) daily stress for 2h with light , ( c ) daily stress for 2h in dark , and ( d ) daily stress for 6h with light . - pubmed
We have successfully set up an animal model , which studied the effect of chronic stress on oral carcinoma growth rate and progression . - pubmed
Damage severity on soybean seeds was significantly reduced , compared with the untreated control , by both bacterial strains ; however , the individual application of phosphite showed to be least effective in controlling M. - pubmed
Persistent infection with high - risk human papillomaviruses ( HR - HPVs ) is the most important risk factor . - pubmed
, yeast grown on galactose versus glucose , or normal versus cancer cells ) . - pubmed
A 46 - year - old woman on hemodialysis due to end - stage renal disease was admitted for repeated thrombus formation in previously implanted drug - eluting stents in the right coronary artery . - pubmed
Bilateral occipital extradural hematoma in a child . - pubmed
Extradural hematoma ( EDH ) occurs in approximately 2 % of all patients with head injuries . - pubmed
Bilateral EDHs account for 2 - 10 % of all acute EDHs in adults but are exceedingly rare in children . - pubmed
EDHs in children are more frequently venous ( from tears of a dural sinus or diploic veins ) and consequently have a better prognosis than EDHs in adults . - pubmed
We are reporting such rare form of injury as bilateral occipital EDH with supratentorial extension in 12 years child following road traffic accident . - pubmed
Human parvovirus B19 ( B19V ) infection causes a number of diseases in humans , and , in some circumstances , can be life threatening . - pubmed
These groups included anemia patients , Mycoplasma pneumonia- and Treponema pallidum - infected patients , HIV - positive individuals , and healthy blood donor volunteers . - pubmed
The analogue 4 - NH2BS - THQ demonstrated a broader spectrum of activity than BS - THQ , with a minimum inhibitory concentration of 100 microg / mL against reference strains of S. - pubmed
BACKGROUND : Rabies is a global problem which occurs in more than 150 countries and territories including Sri Lanka , where human deaths from rabies are in decline whilst resources incurred for prevention of rabies are in sharp incline over the years . - pubmed
To characterize sugar glider RVA in detail , one strain , RVA / SugarGlider - tc / JPN / SG385 / 2012 / G27P[36 ] ( SG385 - tc ) , was isolated . - pubmed
of strain SG385 - tc had diarrhoea and the 50 % diarrhoea - inducing dose ( DD50 ) of strain SG385 - tc in suckling mice was 1.2 x 104 f.f.u . - pubmed
Prevalence of gastrointestinal helminths and management practices for dogs in the Greater Accra region of Ghana . - pubmed
Toxocariosis and ancylostomosis remain the most important parasitic infections affecting companion animals worldwide and pose a risk to animal and human health . - pubmed
Management practices for control of helminths in dogs were assessed through questionnaire interviews of the dog owners . - pubmed
Hookworm eggs were found in 178 ( 46.8 % ) dogs , Toxocara canis eggs in 22 ( 5.8 % ) and mixed infections of hookworms and T. - pubmed
Younger women will use botanicals for urinary tract infections , especially Vaccinium macrocarpon ( cranberry ) , where there is evidence for efficacy . - pubmed
Some examples include Vitex agnus - castus ( chasteberry ) , Angelica sinensis ( dong quai ) , Viburnum opulus / prunifolium ( cramp bark and black haw ) , and Zingiber officinale ( ginger ) . - pubmed
Pregnant women have also used ginger for relief from nausea . - pubmed
Dentin hypersensitivity - like tooth pain seen in patients receiving steroid therapy : An exploratory study . - pubmed
To ascertain whether steroid therapy evokes dentin hypersensitivity ( DH)-like tooth pain , we performed a study based on compelling evidence from patients receiving steroid therapy . - pubmed
The prevalence of SD tooth pain was 17.7 % ( 39/220 patients ) . - pubmed
SD tooth pain was significantly more frequent in pulse therapy patients than in non - pulse therapy patients ( p & lt ; 0.05 ) . - pubmed
It is even rarer in patients with no previous known risk factors for either tumour . - pubmed
Here , we present a case of synchronous non - functioning pituitary adenoma with suprasellar and olfactory groove meningiomas in a patient without previous irradiation . - pubmed
METHODS : The tumours were diagnosed on MRI in the 65 - year - old patient who presented with patchy visual deficits . - pubmed
Early detection of West Nile virus in France : quantitative assessment of syndromic surveillance system using nervous signs in horses . - pubmed
In our study , we assessed whether or not data collected by the passive French surveillance system for the surveillance of equine diseases can be used routinely for the detection of WNV . - pubmed
High - frequency repetitive transcranial magnetic stimulation for treating moderate traumatic brain injury in rats : A pilot study . - pubmed
Moderate TBI was induced in adult male Sprague Dawley rats using Feeney 's weight - dropping method . - pubmed
We present a case report of recurrent gastric cancer with bone marrow metastasis in a patient with no evidence of systemic disease on follow - up for two years post surgical resection . - pubmed
METHODS : We reviewed the medical records of a patient who presented with metastatic gastric adenocarcinoma to the bone marrow two years post R0 subtotal gastrectomy with Roux - en - Y gastrojejunostomy without evidence of systemic disease on follow up for two years . - pubmed
The data and strains described here will provide a valuable guide and resource for future functional exploration of C. - pubmed
Short - term treatment with eicosapentaenoic acid improves inflammation and affects colonic differentiation markers and microbiota in patients with ulcerative colitis . - pubmed
In this pilot study we evaluated the effect of Eicosapentaenoic acid as free fatty acid ( EPA - FFA ) supplementation on mucosal disease activity , colonic differentiation markers and microbiota composition in UC patients . - pubmed
In conclusion , EPA - FFA supplementation reduced mucosal inflammation , promoted goblet cells differentiation and modulated intestinal microbiota composition in long - standing UC patients . - pubmed
Non - traumatic OHCA patients transferred to the hospital from April 2013 through August 2016 were analyzed . - pubmed
Proangiogenic effects of tumor cells on endothelial progenitor cells vary with tumor type in an in vitro and in vivo rat model . - pubmed
The present study aimed at investigating the influence of 4 different tumor types on angiogenic properties of EPCs in an in vitro and in vivo rat model . - pubmed
Coinjection of encapsulated tumor cells , especially mammary carcinoma cells , and EPCs in a rat model confirmed a contributing effect of EPCs in tumor vascularization . - pubmed
The present study will contribute to a better understanding of tumor - induced vascularization , thus facilitating the development of therapeutic strategies targeting tumor - EPC interactions.-An , R. , Schmid , R. , Klausing , A. , Robering , J. W. , Weber , M. , Bauerle , T. , Detsch , R. , Boccaccini , A. R. , Horch , R. E. , Boos , A. M. , Weigand , A. Proangiogenic effects of tumor cells on endothelial progenitor cells vary with tumor type in an in vitro and in vivo rat model . - pubmed
Objective : To investigate the clinical value of Bayesian network in predicting survival of patients with advanced gallbladder cancer(GBC)who underwent curative intent surgery . - pubmed
NMLN , margin , T staging and pathological grade are the top 4 risk factors affecting the survival of patients with advanced GBC who underwent curative resection . - pubmed
Streptococcus pneumoniae is the major bacterial cause of community - acquired pneumonia , and the leading agent of childhood pneumonia deaths worldwide . - pubmed
Neutrophil uptake and killing of the serotype 3 strain was significantly impaired compared to the serotype 4 strain and depletion of neutrophils with antibody enhanced survival of mice infected with the highly encapsulated SRL1 strain . - pubmed
Age - related changes in the tactile pressure sensitivity threshold in the sole of the foot in diabetic patients . - pubmed
[ Purpose ] Patients diagnosed with diabetes mellitus ( DM ) are known to experience sensory disturbances in their feet secondary to diabetic neuropathy ( DN ) . - pubmed
The sole of the foot tactile pressure sensitivity threshold in patients with DM was evaluated in addition to examining age - related effects based on the sites studied . - pubmed
Whether the tactile pressure sensitivity threshold in the sole of the foot in elderly patients with DM was associated with the duration of DM or aging was evaluated . - pubmed
[ Participants and Methods ] Our study included 204 patients with DM ( 136males and 68 females ) . - pubmed
Reductions in lung metastases were demonstrated for two analogs in a late - stage experimental mouse metastasis model , and one analog completely inhibited formation of liver metastases in an orthotopic xenograft mouse model of pancreatic cancer . - pubmed
CASE PRESENTATION : We present a rare case of a 49 - year - old Egyptian man who presented to our emergency department complaining of cough and vague abdominal discomfort who was found to have Chilaiditi syndrome diagnosed radiologically by computed tomography scan . - pubmed
We aimed to investigate the prognostic value of serum cell death markers in patients with hepatitis B virus ( HBV)-related acute decompensation ( AD ) of cirrhosis with and without acute - on - chronic liver failure ( ACLF ) . - pubmed
We studied two cohorts - cohort 1 : 201 outpatients with stable chronic hepatitis B ( 49 cirrhosis ) ; cohort 2 : 232 inpatients with HBV - related cirrhosis admitted for AD . - pubmed
The study included 51 patients with RA . - pubmed
ACD was found in 37.3 % of patients , IDA in 11.8 % , and combined ( ACD / IDA ) in 17.6 % . - pubmed
IDA alone or combined with ACD was encountered in about a third of patients . - pubmed
The acute psychological pressure score and the psychological pressure self - test score in the experimental group were both lower than that in the control group ( P & lt ; .05).Comprehensive nursing intervention for otolaryngology patients was associated to relieving pain after the operation and psychological pressure of patients in the short and long term . - pubmed
infection in sheep population of Ladakh , India . - pubmed
Ladakh is the high altitude ( 11,184 ft above sea level ) cold desert region in the state of Jammu & amp ; Kashmir ( India ) , where winter temperature goes below - 35 C. A total of 37 faecal samples were collected from local Changthangi and Russian merino sheep of the Leh region of Ladakh , having the history of diarrhoea and emaciation , followed by death . - pubmed
infection in adult sheep from India . - pubmed
Sensitivity and specificity of meningeal signs in patients with meningitis . - pubmed
In this study , we examined the involvement of cell death signaling in tissue - size determination using Drosophila wing as a model . - pubmed
INTRODUCTION : Mantle cell lymphoma ( MCL ) is a subtype of B - cell non - Hodgkin lymphoma ( NHL ) , and the purpose of this study was to evaluate the prognostic value of 25 - hydroxy vitamin D [ 25 -( OH ) D ] deficiency among patients with MCL . - pubmed
MATERIALS AND METHODS : Seventy MCL patients with serum 25 -( OH ) D were enrolled in this study . - pubmed
The effects of ginger supplementation on inflammatory , antioxidant , and periodontal parameters in type 2 diabetes mellitus patients with chronic periodontitis under non - surgical periodontal therapy . - pubmed
Background : The aim of this study was to evaluate the effects of ginger supplementation on inflammatory , antioxidant , and periodontal parameters in type 2 diabetes mellitus ( T2DM ) patients with chronic periodontitis ( CP ) under non - surgical periodontal therapy ( NSPT ) . - pubmed
Material and methods : In this double - blind clinical trial study , 46 T2DM patients with CP were randomly allocated to intervention and control groups and received either 4 tablets 500 mg ( 2 g ) ginger or placebo twice a day for 8 weeks . - pubmed
Conclusion : It is recommended that ginger supplementation along with NSPT may be effective in the improvement of inflammation , oxidative , and periodontal status in T2DM with CP . - pubmed
Results : Thirteen studies involving 1172 cancer patients and 32 TCGA cancer types involving 9676 cancer patients were eventually selected . - pubmed
The initial FDA instructions for use ( IFU ) limited its use to patients 22 years old or older with wide - necked large or giant aneurysms of the internal carotid artery ( ICA ) from the petrous segment to superior hypophyseal artery / ophthalmic segment . - pubmed
BACKGROUND : Ordinary meta - analyses indicate that magnesium sulphate ( MgSO4 ) treatment to women at imminent risk for preterm delivery decreases the offspring 's risk of cerebral palsy ( CP ) . - pubmed
Increasing psychophysical evidence suggests that specific image features - or statistics - can appear unpleasant or induce visual discomfort in humans . - pubmed
Administration of secretome from human placental stem cell conditioned media improves recovery of erectile function in the pelvic neurovascular injury model . - pubmed
CONCLUSION : Injection of the secretome isolated from human PSC improves erectile functional recovery and histological structure in a rat model of neurovascular injury - induced ED . - pubmed
MATERIALS AND METHODS : The subjects were 701 consecutive patients ( mean age 74 + -9 years ; 492 men ) with 817 de novo SFA lesions treated with BNS implantation between January 2004 and September 2015 . - pubmed
Uncariae Ramulus Cum Uncis ( UR ) has a long - term history for the treatment of cardiovascular and central nervous systems disorders in China and Eastern Asia . - pubmed
BACKGROUND : In the field of melanoma , clinical trials evaluating the impact of sentinel node biopsy , completion lymph node dissection and adjuvant medical therapies on patient outcomes have provided evidence that has changed practice significantly over the past five years . - pubmed
OBJECTIVES : Coronavirus disease 2019 ( COVID-19 ) , caused by the novel severe acute respiratory syndrome coronavirus 2 ( SARS - CoV-2 ) , has become a global pandemic , raising widespread public health concerns . - pubmed
Response to : ' Antirheumatic drugs , B cell depletion and critical COVID-19 : correspondence on ' Clinical course of coronavirus disease 2019 ( COVID-19 ) in a series of 17 patients with systemic lupus erythematosus under long - term treatment with hydroxychloroquine by Mathian et al ' by Notz et al . - pubmed
INTRODUCTION : Vancomycin remains first - line therapy for methicillin - resistant Staphylococcus aureus ( MRSA ) blood stream infections ( BSI ) ; however , its toxicity and reported clinical failures are well established . - pubmed
aureus BSI was adjusted and applied to this cohort to compare vancomycin - treated versus daptomycin / ceftaroline - treated patients . - pubmed
During the mean follow - up ( FUP ) of 275 + - 88 days , patients in the PCI group reported less physical activity limitations ( 72.7 + - 21.3 versus 60.5 + - 27 , P = 0.014 ) , less frequent angina episodes ( 89.8 + - 17.6 versus 76.8 + - 27.1 , P = 0.006 ) , better QoL ( 79.9 + - 22.7 versus 62.5 + - 25.5 , P = 0.001 ) , greater treatment satisfaction ( 91.2 + - 13.6 versus 81.4 + - 18.4 , P = 0.003 ) , and borderline differences in angina stability ( 61.2 + - 26.5 versus 51.0 + - 23.7 , P = 0.046 ) compared to patients in the OMT group . - pubmed
METHODS : Patients thought - on the basis of having a firm , immobile mass centered on the lacrimal sac fossa - to possibly have lacrimal sac malignancy were identified from a database of biopsies between 1989 and 2020 . - pubmed
One - fifth of malignant lesions had pain , whereas all the benign conditions were painless , and acute dacryocystitis was relatively uncommon - occurring in only 13 % of patients . - pubmed
A Pilot Study of Switching Electroconvulsive Therapy for Patients With Treatment Resistant Schizophrenia or Mood Disorder . - pubmed
Neonatal GAT tolerance could be transferred in adult and involved suppressor T cells in the two inbred strains , whereas the GT - specific immune suppression was not demonstrable in newborn BALB / c mice . - pubmed
Chronic haemolytic anaemia in two patients heterozygous for erythrocyte pyruvate kinase deficiency . - pubmed
Two patients with mild chronic haemolytic anaemia , a mother and her son , were found to be heterozygous for erythrocyte pyruvate kinase deficiency . - pubmed
The relationship between neurovirulence and induction of hydrocephalus was investigated for a measles virus temperature - sensitive mutant and its revertant . - pubmed
The evidence derives mainly from experiments on Schistosoma mansoni infections in the mouse with their immune status variously modulated ; this review emphasises praziquantel ( PZQ ) , which is now the main drug used for treatment of human schistosomiasis . - pubmed
The potential relevance of these observations for enhancing the efficacy of drugs currently used to treat human schistosomiasis , and for devising novel therapeutic strategies , is discussed . - pubmed
In this updated and expanded retrospective analysis , the treatment records of 24 patients with brain metastases from nonseminomatous germ cell testicular tumors ( NSGCT 's ) treated at the Indiana University Department of Radiation Oncology from 1975 through 1988 were reviewed . - pubmed
Group 1 ( n = 10 ) consisted of patients who presented initially with brain metastases and had no prior systemic treatment . - pubmed
Group 3 ( n = 10 ) consisted of those patients who were initially treated with PVB + /- doxorubicin or bleomycin , etoposide , and cisplatin ( BEP ) and eventually developed progressive disease and brain metastases . - pubmed
Patients with brain metastases who have potentially controllable systemic disease should be treated curatively with WBRT ( 5000 cGy/25 fractions ) + /- surgical excision and concomitant chemotherapy . - pubmed
Forty - three patients with recurrent and metastatic squamous cell carcinoma of the cervix received a program of sequential combination chemotherapy incorporating induction with cisplatin , vinblastine , and bleomycin ( PVB ) and subsequent consolidation with 5 - fluorouracil , doxorubicin , cyclophosphamide , and vincristine ( FACV ) . - pubmed
However , the only cumulative toxicity was peripheral neuropathy , although this was only moderate to severe in 2 patients . - pubmed
The influence of Mesocestoides corti on subsequent Angiostrongylus cantonensis infections in mice . - pubmed
The influence of Mesocestoides corti on subsequent Angiostrongylus cantonensis infection in mice ( C57BL/6 and BALB / c ) was assessed . - pubmed
Both strains of mice infected with M. - pubmed
corti were given A. cantonensis infection 18 days later , but pre - existing M. - pubmed
BALB / c mice with mixed parasite infections showed low morbidity and mortality as compared with mice singly infected with A. cantonensis and some mice demonstrated a pulmonary migration of intracranial worms . - pubmed
C57BL/6 mice with mixed parasite infections failed to resist A. cantonensis reinfection . - pubmed
corti biomass was significantly higher in mice with mixed parasite infections than mice with monoinfection with M. - pubmed
These data suggest a distinct difference in response to A. cantonensis infection between C57BL/6 and BALB / c mice , and the induction of immunosuppression in both mouse strains following M. - pubmed
Based on these data , the recommended amikacin dosage in chickens is 20 mg / kg body weight every 8 h. - pubmed
An illustrative patient is presented in whom these vessels were used for a combined serratus anterior - latissimus dorsi free muscle flap for sacral wound coverage . - pubmed
Four patients have died of their disease , and there was one treatment - related death . - pubmed
The anti - inflammatory effects of D - myo - inositol-1.2.6 - trisphosphate ( PP56 ) on animal models of inflammation . - pubmed
Systemic infection caused by Penicillium decumbens in a patient with acquired immunodeficiency syndrome . - pubmed
The prognosis of both operated and non - operated tumour patients , is determined exclusively by the recurrence and progression of the tumour disease . - pubmed
Time course of change in oxygen saturation and peak expiratory flow in children admitted to hospital with acute asthma . - pubmed
Serial measurements of SaO2 were made in 47 children during an acute attack of asthma that required admission to hospital . - pubmed
These data suggest that in children admitted to hospital for acute asthma arterial oxygen saturation is low at admission , recovers more slowly than airway function , reflects bronchodilatation with salbutamol only when SaO2 is low , and recovers more rapidly in younger children than in older children . - pubmed
A randomized , double - blind trial was performed to assess serological response and clinical protection for acute gastroenteritis due to rotavirus in 103 children aged 6 to 18 months , after a single dose of RIT 4237 live attenuated bovine rotavirus vaccine or placebo . - pubmed
One hundred sixty patients intolerant of or allergic to sulfasalazine ( Salazopyrin , Azulfidine ) participated in an open tolerance study of azodisal sodium ( Dipentum ) . - pubmed
More than 4 of every 5 patients tolerated azodisal sodium well , but 12.5 % of patients stopped medication because of diarrhea . - pubmed
Even after 7 patients who had also experienced diarrhea when taking sulfasalazine were excluded , there still remained a group of patients ( 9.8 % ) who had to discontinue azodisal sodium because of diarrhea . - pubmed
Of these , 23.1 % of the patients treated with azodisal sodium and 44.9 % of the patients treated with placebo had a clinical and sigmoidoscopic relapse during a 6 - mo trial period ( p = 0.02 ) . - pubmed
Changes in ambulatory activity and dopamine turnover in streptozotocin - induced diabetic rats . - pubmed
We observed decreased ambulatory activity in STZ - induced diabetic rats during the dark , but not the light , cycle . - pubmed
Moreover , ambulatory activity in STZ - induced diabetic rats gradually decreased , while the blood glucose level rose . - pubmed
The present study suggests that there are metabolic abnormalities in the striatum dopaminergic neurons of STZ - induced diabetic rats associated with decreased ambulatory activity . - pubmed
In 72 % of 143 patients undergoing a second coronary bypass grafting , mural or occlusive late thrombosis was observed histologically in 69 % of 173 resected grafts . - pubmed
Alterations in appendicular skeletal mass in patients with rheumatoid , psoriatic , and osteoarthropathy . - pubmed
Appendicular bone mass was measured in a series of 50 patients with non - steroid treated rheumatoid arthritis , 20 with polyarticular seronegative psoriatic arthritis , and 30 with osteoarthrosis , and compared with that of 40 controls of similar age and sex . - pubmed
Distal forearm bone mineral content was reduced in patients with rheumatoid and psoriatic arthritis and increased in those with osteoarthrosis . - pubmed
The increase in bone mass in patients with osteoarthrosis was confined to those with isolated large joint disease and was not found in those with primary generalised osteoarthrosis . - pubmed
Because of the observed ability of retinoids to reverse other dysplastic conditions in vitro and in vivo , a number of clinical studies have been carried out of the effect of these agents on cervical dysplasia , with the object of developing a means of chemoprevention of cervical malignancies in women at risk . - pubmed
The outcome of the latter investigation will have important implications , not only for the management of patients with cervical dysplasia but also for therapeutic approaches to other precancerous conditions . - pubmed
The authors retrospectively evaluated their radiographic experience with this injury in 27 patients over a 24 - month period . - pubmed
CT studies provided better delineation of the fracture in all 21 patients and significant additional information in five patients ( 24 % ) . - pubmed
Seven patients ( 26 % ) suffered initial neurologic sequelae in association with the C-2 injury . - pubmed
Nine patients had additional sites of fracture , including seven with associated C-1 ring disruption ( 26 % ) . - pubmed
Extension of the fracture line into the transverse vertebral artery foramen led to vertebral artery injury and cerebellar embolization in one patient . - pubmed
OSA has been shown to have developed in two patients with HSS . - pubmed
Reduction of aspirin - induced fecal blood loss with low - dose misoprostol tablets in man . - pubmed
This indicates a potential role for misoprostol in the prevention of gastric mucosal damage in selected patients . - pubmed
Serum 18 - hydroxycorticosterone , aldosterone , and potassium were measured under basal conditions in 34 patients with documented primary aldosteronism , 10 patients with essential hypertension , and 9 normal subjects . - pubmed
The results revealed that 22 of 23 patients with aldosterone - producing adenomas had 18 - hydroxycorticosterone levels greater than 100 ng / dl , and all 9 patients with idiopathic adrenal hyperplasia had plasma levels less than 100 ng / dl . - pubmed
Two patients with unusual macromicronodular hyperplasia of the adrenal glands had levels greater than 100 ng / dl . - pubmed
We found a significant relationship between serum potassium and the ratio of 18 - hydroxycorticosterone to aldosterone in patients with idiopathic adrenal hyperplasia , but not in those with an aldosterone - producing adenoma . - pubmed
Observations on commensal cultures of Bordetella bronchiseptica and rat hepatoma cells . - pubmed
Identification of filamentous micro - organisms of the human dental plaque by immuno - fluorescence . - pubmed
[ The state of the blood coagulation system in acute appendicitis patients ] . - pubmed
Diuresis in newborn rat given intravenous water or salt solution . - pubmed
The effects of feeding saturated and eucaloric unsaturated fat - rich diets on lipemia and insulinemia in female Brown Norway rats have been compared . - pubmed
[ Programmed electric stimulation in a pregnant woman with mitral valve defect and ventricular arrhythmia with bradycardia ] . - pubmed
In order to search into the mechanism of the potassium contracture of the dog coronary artery the effects of procaine were studied in the isolated smooth muscle preparation of the dog coronary artery . - pubmed
These findings suggest that the potassium contracture of the dog coronary artery is dependent on the calcium - induced calcium release mechanism . - pubmed
The liability to encounter severe side effects is often enhanced in patients with underlying cardiovascular diseases , which may change the usual drug action either by inducing modifications of the drug pharmacolinetic or by altering the receptor sensitivity . - pubmed
A few severe chromosome aberrations , such as dicentrics or translocations , appeared in the control animals as well as in the lead - treated ones , during the course of the experiment . - pubmed
In clinical trials in patients with rheumatic diseases or pain arising from other conditions , it was as effective an analgesic as standard piroxicam , and showed a faster onset of action on the first day of treatment . - pubmed
In short term pharmacodynamic studies in healthy volunteers , piroxicam - beta - cyclodextrin was equivalent to or tended to show less gastrointestinal mucosal toxicity than standard piroxicam , as assessed by endoscopy and faecal blood loss . - pubmed
Thus , piroxicam - beta - cyclodextrin is an effective agent in patients with rheumatic diseases or other pain states . - pubmed
In four patients ( group 1 ) , coronary ischemia had developed 0.5 - 70 months ( mean , 31 months ) after IMA - to - coronary artery bypass surgery . - pubmed
In four other patients ( group 2 ) , atherosclerotic subclavian stenosis had developed proximal to a donor IMA before planned bypass surgery . - pubmed
RESULTS : Group 1 patients were free of myocardial ischemia at follow - up ( mean follow - up , 39.0 months ; range , 14 - 101 months ) . - pubmed
We used artificial augmentation of CO2 at a rate of 1 l / min after preoxygenation with 100 % O2 to test for apnea in 34 patients with suspected brain death . - pubmed
All CBA mice that had been immunised by means of four successive inoculations of Plasmodium berghei NK65 , each inoculation being followed by chemotherapy , survived an intravenous challenge inoculation of parasite , with 4/12 mice developing patent parasitaemia that resolved within 2 weeks . - pubmed
Effects of cyclopentenone prostaglandins on myeloid cells during early infection with HTLV - I. - pubmed
Human myeloid cell lines at different stages of differentiation ( K562 , HL60 and U937 ) were used to analyze the permissivity of the myelomonocytic lineage to acute infection with human T - cell leukemia virus type - I ( HTLV - I ) after cell - to - cell transmission and to evaluate the effect of cyclopentenone prostaglandins ( PG ) A1 and PGJ2 on virus transmission , proliferation of recipient cells and cell - mediated cytotoxicity against virus - donor cells . - pubmed
A study of obese cats on a calorie - controlled weight reduction programme . - pubmed
Twenty - two domestic cats were fed a commercial low calorie diet for the management of obesity for up to 18 weeks and showed an average weight loss of 13.5 per cent of their body - weight . - pubmed
There was no indication that a steady weight loss over the study period had any adverse effect on the hepatic function or general health of the cats . - pubmed
Efficacy of erythromycin compared with penicillin / streptomycin for the treatment of virulent footrot in sheep . - pubmed
Antipsychotic agents , most often used for treatment of schizophrenia , are sometimes prescribed for the agitated patient with an organic brain disorder . - pubmed
We report the case of a brain - injured patient who was prescribed chlorpromazine for agitation and who developed a delusional state while taking this antipsychotic agent . - pubmed
Caution is advised when prescribing neuroleptics for patients with traumatic brain injury , especially those agents with significant cognitive side - effects or with a significant potential to precipitate seizures . - pubmed
Tissue and plasma concentrations of pentose - derived glycation end - products ( " pentosidine " ) are elevated in diabetic patients with normal renal function and in both diabetic and nondiabetic patients with end - stage renal disease . - pubmed
We conclude that renal failure is the major factor accounting for the accumulation of pentosidine in both diabetic and nondiabetic patients with end - stage renal disease . - pubmed
Coronary artery bypass grafting in a patient with multiple intracranial aneurysms and recent subarachnoid hemorrhage . - pubmed
The present brief review deals specifically with data obtained with urapidil in the treatment of elderly hypertensive patients . - pubmed
Some of these data , dealing with 245 patients aged & gt ; or = 65 years , have previously been published , but additional data from more than 5000 hypertensive patients in this age group on file will be reviewed as well . - pubmed
Random amplified polymorphic DNA ( RAPD ) analysis was applied to genomic DNA from nineteen yeast strains belonging to the genera Saccharomyces and Zygosaccharomyces . - pubmed
Photoinduced toxicity of PAHs to the foliar regions of Brassica napus ( canola ) and Cucumbis sativus ( cucumber ) in simulated solar radiation . - pubmed
napus ( canola ) and Cucumbis sativus ( cucumber ) , were chosen to test the photoinduced toxicity of six PAHs ( anthracene , phenanthrene , benzo ( a ) anthracene , benzo ( a ) pyrene , flouranthene , and pyrene ) . - pubmed
SUBJECTS : 52 patients who underwent gastric resection for gastric cancer that was invading the muscularis propria , and for whom clinical follow - up data were available . - pubmed
Microdialysis probe delivery of an isotonic high - K+ solution to the rat amygdala for 60 - 70 min produces neuronal necrosis , edematous neuropil and increases in extracellular glutamate and aspartate . - pubmed
Oxidative stress is postulated to be increased in patients with IDDM . - pubmed
RESULTS : HIV - positive men were more likely to develop HSIL than HIV - negative men relative risk ( RR ) , 3.7 ; 95 % confidence interval ( CI ) , 2.6 - 5.7 . - pubmed
Reduced incidence of septic arthritis in children by Haemophilus influenzae type - b vaccination . - pubmed
In many countries Haemophilus influenzae type b ( Hib ) is the second most common cause of septic arthritis in children . - pubmed
Human arachnoid villi response to subarachnoid hemorrhage : possible relationship to chronic hydrocephalus . - pubmed
A case is presented in which the revised diagnosis of infrapatellar contracture syndrome was made after noting delayed progress in the rehabilitation of an active female patient with a presumed anterior horn medial meniscus tear and a contracted patellar tendon . - pubmed
Group D rats ' lateral skin necrosis compared significantly less with group C ( p & lt ; 0.001 ) . - pubmed
The signs among infected cattle and sheep were high fever , icterus , bloody diarrhoea and abortion . - pubmed
The same suspensions caused paralysis and mortalities two to three days post intracerebral injection in mice . - pubmed
Importation of infected ruminants , especially camels from the Sudan , is the principal source of infection . - pubmed
The patient - doctor relationship plays a crucial role in conservative treatment of sciatic pain . - pubmed
Eight patients ( 9 fractures ) who have been treated with Dall - Miles plating in this unit between April 1996 and October 1997 for ipsilateral periprosthetic fractures around total hip replacement ( 7 cases ) and total knee replacement ( 2 cases ) have been reviewed . - pubmed
Subcutaneous emphysema developed in three patients with no sequelae . - pubmed
An episode of acute upper airway obstruction was caused by a lingual haematoma , when a patient with end stage renal failure suffered a hypocalcaemic fit and bit his tongue . - pubmed
We have studied the recruitment and roles of distinct dendritic cell ( DC ) precursors from the circulation into Propionibacterium acnes - induced granulomas in mouse liver . - pubmed
Diffuse cortical reduction of neuronal activity in unipolar major depression : a retrospective analysis of 337 patients and 321 controls . - pubmed
All investigations were included comparing regional cerebral blood flow ( rCBF ) or glucose metabolism ( rCMRGlc ) between acutely depressed unipolar major depressive patients and healthy controls . - pubmed
In patients with unipolar major depression rCBF and rCMRGlc were lowered in left ( -4.4 % , P = 0.022 ) and right frontal ( -3.2 % , P = 0.053 ) , left ( -1.7 % , P = 0.061 ) and right temporal ( -3.0 % , P=0.003 ) , left ( -6.5 % , P = 0.002 ) , and right parietal ( -8.8 % , P=0.001 ) , and left ( -6.6 % , P = 0.083 ) and right occipital cortex ( -4.2 % , P = 0.02 ) . - pubmed
Liver cirrhosis was induced by CCl ( 4 ) inhalation and phenobarbital in Wistar rats . - pubmed
Clinical impact of endoscopic ultrasound - guided fine needle aspiration biopsy in patients with upper gastrointestinal tract malignancies . - pubmed
BACKGROUND AND STUDY AIMS : Several studies have evaluated the accuracy of endoscopic ultrasound - guided fine - needle aspiration biopsy ( EUS - FNAB ) in the upper gastrointestinal tract , but so far no studies have specifically evaluated the clinical impact of EUS - FNAB in upper gastrointestinal tract cancer patients . - pubmed
PATIENTS AND METHODS : Between 1997 and 1999 , 307 consecutive patients were referred for EUS with a diagnosis or strong suspicion of esophageal , gastric or pancreatic cancer ; 274 patients were potential candidates for surgical treatment and had EUS . - pubmed
We examined 40 CD patients [ 31 not being treated with a gluten - free diet ( GFD ) and 9 being treated with a GFD ] and 30 non - CD patients . - pubmed
BACKGROUND : Acute septic cholecystitis ( AC ) remains a difficult problem in patients with coexisting severe illness , and ultrasonographically guided percutaneous puncture and drainage of the gallbladder ( PTBD ) may be an alternative treatment in this context . - pubmed
Seven patients had an intraperitoneal bile leak and 2 had worsening septicemia . - pubmed
Only 60 patients survived another 6 months because of general debility and other diseases . - pubmed
Twenty - eight ( 47 % ) of the remaining patients had at least one recurrent episode of AC . - pubmed
A common bile duct stone was demonstrated in 4 patients after ERCP and indicative signs were found in another 5 ( 10 % ) . - pubmed
CONCLUSIONS : PTBD remains a good option in patients with septic AC who have severe coexisting disease and may be too ill to undergo an operation . - pubmed
Fifty - five patients were accrued ( phase I : 15 ; phase II : 40 ) and all are evaluable for response and toxicity : median age = 58 ( 40 - 72 ) ; PS = 1 ( 0 - 2 ) ; gender = 48 males , 7 females ; stages IIIA = 8 , IIIB = 19 , IV = 28 ; and histologies were adenocarcinoma ( 29 ) , squamous ( 20 ) , large cell ( 6 ) . - pubmed
Nosocomial outbreak of Kluyvera cryocrescens bacteremia . - pubmed
METHODS : Human articular chondrocytes were isolated from the femoral head and tibial plateau of patients undergoing knee joint replacement for OA . - pubmed
Blunt injury of the innominate artery associated with a bovine arch . - pubmed
UNLABELLED : In patients with myocardial infarction ( MI ) , an expansion of the remote normal regions of the left ventricle is often observed . - pubmed
RESULTS : The LV end - diastolic volume index was significantly larger in patients with MI without beta - blockers than in normal control subjects ( 101 + /- 22.5 vs. 61.6 + /- 12.8 mL x m(-2 ) ; P & lt ; 0.001 ) . - pubmed
There was no significant difference in the heart rate x pressure product between the patients with MI without beta - blockers and the normal control subjects ( 8,229 + /- 1,503 vs. 8,311 + /- 1,311 mm Hg x min(-1 ) ) . - pubmed
The K(mono ) in remote normal regions was significantly greater in patients with MI without beta - blockers even when compared with the highest K(mono ) on the anteroseptal wall of the left ventricle in normal control subjects ( 0.078 + /- 0.022 vs. 0.065 + /- 0.007 min(-1 ) ; P & lt ; 0.01 ) . - pubmed
No significant difference in the LV end - diastolic volume index was found between the MI patients with and without beta - blockers . - pubmed
The levels of plasma NO in patients with PIH were significantly lower than those in healthy pregnancy . - pubmed
Short - term depression at primary afferent synapses in rat substantia gelatinosa region . - pubmed
To study the short - term depression at primary afferent synapses between Adelta fibers and substantia gelatinosa ( SG ) neurons in the spinal cord , transverse spinal cord slices with dorsal root attached were made from young rats . - pubmed
casei ) have been carried out using strain ATCC 393 ( pLZ15- ) . - pubmed
Four strains of L. - pubmed
These tests showed that strains of ATCC 393 T obtained from independent public type - culture collections were significantly different from the plasmid - free ( pLZ15- ) strains of ATCC 393T. - pubmed
Complete sequencing of the 16S rDNA of one representative strain from each group revealed that strain ATCC 393 T from culture collections was 99 % similar to Lactobacillus zeae ATCC 15820 T and that the strain so far considered as L. - pubmed
All data obtained in this work indicate that the ancestral strain of ATCC 393 ( pLZ15- ) might never have been the strain that is now available from culture collections . - pubmed
While for young patients , the diagnosis of pituitary micro - adenoma and use of X - Knife radiosurgery should be very cautious , otherwise hypopituitarism might be resulted . - pubmed
Ventricular fibrillation in hypothermic dogs . - pubmed
Human ovarian cyst gps , which belong to the complex type of glycoform , comprise most of the structural units . - pubmed
Axonal degeneration in paraplegin - deficient mice is associated with abnormal mitochondria and impairment of axonal transport . - pubmed
In several neurodegenerative diseases , axonal degeneration occurs before neuronal death and contributes significantly to patients ' disability . - pubmed
Paraplegin - deficient mice are affected by a distal axonopathy of spinal and peripheral axons , characterized by axonal swelling and degeneration . - pubmed
Results of operative treatment of 60 patients with pheochromoblastoma were analyzed . - pubmed
In 8 ( 13.3 % ) patients with the spread metastases revealed and they were directed to symptomatic therapy by their residence . - pubmed
The recurrence occurrence after primary operation performance is unfavorable prognostic feature : 55.8 % of such patients were considered incurable . - pubmed
PURPOSE : To evaluate the duration of the effect of intravitreal triamcinolone acetonide on visual acuity in patients with diffuse diabetic macular edema . - pubmed
METHODS : Subjects were 31 patients ( 38 eyes ) with diffuse diabetic macular edema who received an intravitreal injection of 20- to 25 - mg triamcinolone acetonide . - pubmed
CONCLUSIONS : The effect of an intravitreal injection of approximately 20- to 25 - mg triamcinolone acetonide in patients with diffuse diabetic macular edema lasts approximately 7 to 8 months . - pubmed
CONCLUSIONS : Rhesus monkeys respond to either dietary L or Z supplementation with increases in serum xanthophylls and MP , even after life - long xanthophyll deficiency . - pubmed
These animals provide a potential model to study mechanisms of protection from AMD . - pubmed
A case of acute gastrointestinal haemorrhage in a patient with systemic neurofibromatosis is presented . - pubmed
Patients with systolic heart failure and restrictive filling pattern show a lower exercise tolerance than their counterparts with non - restrictive filling . - pubmed
This indicates a significant role of diastolic dysfunction in the development of clinical symptoms in patients with left ventricular systolic impairment . - pubmed
Progress in the understanding of diastolic dysfunction may allow for better evaluation of prognosis and therapeutic efficacy and for monitoring of patients with systolic dysfunction . - pubmed
A slice anatomy study was performed on 12 right wrists of unfixed human cadavers by using the plastination technique . - pubmed
Potentiation of the antitumoral activity of gemcitabine and paclitaxel in combination on human breast cancer cells . - pubmed
The purpose of this study was to evaluate the antitumoral activity of different gemcitabine - based combination on an experimental model of human breast cancer , in order to identify the most effective treatment and to provide a rationale for clinical investigations . - pubmed
Mice bearing CG5 human breast xenografts treated with paclitaxel and gemcitabine in combination showed a significant higher inhibition of tumor growth ( approximately 70 % ) compared to that with either agent alone ( 25 % ) . - pubmed
The opportunities to change the treatment of ovarian cancer will require creative clinical trial design but the next decade promises to be filled the therapeutic advances for patients with ovarian cancer . - pubmed
To date , glyceroneogenesis has only been described in mammals but we demonstrate in this paper that it could exist in the invertebrate Schistosoma mansoni , the parasitic helminth transmitted by fresh water molluscs and responsible for the major human endemic disease , schistosomiasis . - pubmed
Study of reaction norms showed that the genotypes from different animal species are similarly plastic , but there are transgenic models in which adaptation to mechanics is not caused by hypertrophy but by qualitative changes in gene expression . - pubmed
OBJECT : Acute respiratory failure has been observed in patients after external immobilization for displaced odontoid fractures . - pubmed
The authors studied the frequency of respiratory deterioration in the acute management of displaced Type II odontoid fractures to identify patients at risk for respiratory failure . - pubmed
METHODS : The authors conducted a retrospective review of a consecutive series of 89 patients with odontoid fractures who were treated over a 5 - year period to identify 53 patients with displaced Type II odontoid fractures . - pubmed
Of the 32 patients with posteriorly displaced fractures , 13 experienced acute respiratory compromise , whereas only one of 21 patients with anteriorly displaced fractures had respiratory difficulties ( p = 0.0032 ) . - pubmed
CONCLUSIONS : Frequent respiratory deterioration during acute closed reduction of posteriorly displaced Type II odontoid fractures was observed , whereas respiratory failure in patients with anteriorly displaced fractures was rare . - pubmed
PAH is one of the resulting deleterious effects in approximately 15 % of SSc patients . - pubmed
CONCLUSION : Bosentan treatment was well tolerated in this cohort of SSc patients with interstitial lung disease and was effective for treatment of severe PAH in the majority of patients . - pubmed
Atherosclerotic disease was discovered in 17 % of the patients . - pubmed
METHODOLOGY : Seventy - four of 281 rectal cancer patients , since the introduction of laparoscopic colorectal surgery in our hospital , have undergone laparoscopic rectal surgery . - pubmed
CONCLUSIONS : Laparoscopic mesorectal excision with preservation of autonomic pelvic nerves for rectal cancer patients including selected advanced lower rectal cancer is favorable . - pubmed
INTRODUCTION : Intermittent pneumatic mechanical compression is commonly applied to obviate venous stasis in patients with increased risk of thromboembolism . - pubmed
Although a central aortic operation alone successfully reversed aortic - type malperfusion in all three patients , it was not effective for branch - type malperfusion in five of six vascular territories . - pubmed
Surgical fenestration did not successfully reverse branch - type renal malperfusion in two patients . - pubmed
Modulation rate transfer functions in bottlenose dolphins ( Tursiops truncatus ) with normal hearing and high - frequency hearing loss . - pubmed
The antirheumatic effect of pirfenidone was compared with a positive control drug , oxyphenbutazone which is used in patients suffering from rheumatoid arthritis , in a double blind clinical trial in humans . - pubmed
No graft loss or hyperthrophic scarring which may be seen at the apex of neovagina after Mc Indoe vaginoplasty was observed during the follow - up period and adequate neovaginal depth were obtained in both of the patients . - pubmed
We show that female mice with defective DNA double - strand break repair had significantly increased frequencies of zygotes with sperm - derived chromosomal aberrations after matings with wild - type males irradiated 7 days earlier with 4 Gy of ionizing radiation . - pubmed
Urinary tract infections are a major source of morbidity among women , with the majority caused by uropathogenic Escherichia coli . - pubmed
There was a good outcome in the majority of patients who presented with arterial gas embolism and were treated with compression . - pubmed
Review : intensified patient care may improve adherence to lipid - lowering medication in primary or secondary prevention of CV disease . - pubmed
METHODS : Rat models of AC ( biliary tract obstruction+E. - pubmed
RESULTS : Severe liver tissue injury in rats with AC was evident as shown by pathological examination . - pubmed
Quantitative risk assessment of human campylobacteriosis related to the consumption of chicken meat in two Italian regions . - pubmed
Campylobacteriosis is the most frequently reported zoonotic disease in humans within the European Union . - pubmed
The consumption of contaminated chicken meat is considered one of the main sources of human infection . - pubmed
The authors developed a simulation model to quantitatively estimate the expected annual number of human cases of campylobacteriosis in the Italian regions of Abruzzo and Molise , due to the cross - contamination during the handling of Campylobacter jejuni contaminated chicken meat in domestic kitchen . - pubmed
The expected percentage of human population , experiencing Campylobacter gastroenteritis episodes every year in Abruzzo e Molise regions , varied between 0.8 % and 1.8 % , according to the dose - response model . - pubmed
With one ( 20 % , p & gt ; 0.05 ) exception none of the children with DCM were overweight or had a family history of diabetes . - pubmed
All five ( 100 % ) children with DCM had been given high cumulative dosage of steroids 18 ( 78.3%)--without DCM ( p & gt ; 0.05 ) . - pubmed
The median age of children with DCM was greater [ 4.3 ( 12.7 - 18.0 ) vs. 7.0 ( 2.3 - 18.0 ) yr , p & lt ; 0.01 ] and duration of follow - up longer [ 5.3 ( 2.3 - 7.0 ) vs. 2.5 ( 0.7 - 7.3 ) yr , p & lt ; 0.05 ] . - pubmed
Four children ( 80 % ) with DCM were pubertal ( p & lt ; 0.05 ) . - pubmed
DCM is frequently observed in liver transplanted children . - pubmed
Albeit the children with DCM were given high cumulative dose of steroids , were older , mostly were pubertal , and had longer duration of follow - up , we can not draw firm conclusions on effects of the risk factors on carbohydrate metabolism because of the small sample size and relatively short duration of follow - up . - pubmed
Unlike fasting measurements , OGTT can detect all children with DCM . - pubmed
The stimulation of DCs by bacterial strains was monitored by the production of nitric oxide ( NO ) , and the colorimetric Greiss assay was used to quantify the level of NO produced . - pubmed
For example , in a human , one of the reasons why the habitual abortion is understood as the failure of the maternal immune system . - pubmed
MATERIALS AND METHODS : Between September 2004 and September 2007 , 269 eligible patients with a clinical suspicion of prostate cancer referred to our department were randomized to an 8 - core lateral ( group 1 ) or a 12 - core lateral and parasagittal ( group 2 ) transrectal ultrasound guided prostate biopsy protocol . - pubmed
PARTICIPANTS : Thirty - one eyes ( 31 patients ) underwent a variety of vitreoretinal procedures using the 27 - gauge transconjunctival MIVS system to treat epiretinal membrane ( n = 10 ) , idiopathic macular holes ( n = 7 ) , diabetic vitreous hemorrhage ( n = 5 ) , vitreous opacity with suspicion of intraocular lymphoma ( n = 4 ) , focal diabetic traction retinal detachment ( n = 3 ) , macular traction syndrome ( n = 1 ) , and macular edema secondary to central retinal vein occlusion ( n = 1 ) . - pubmed
Sixteen out of 26 ( 61.5 % ) GSD I patients in our study had suboptimal levels ( & lt;30 ng / ml ) of 25 - hydroxyvitamin - D ( 25 ( OH ) D ) despite supplementation of vitamin D and/or vitamin D + calcium based on WHO standards in 24/26 ( 92.3 % ) patients . - pubmed
Pseudoaneurysms can be debilitating for patients and occasionally life threatening . - pubmed
Varicella - zoster virus ( VZV ) is a neurotropic human alphaherpesvirus and the causative agent of varicella and herpes zoster . - pubmed
Investigation of VZV neuropathogenesis by infection of human dorsal root ganglion xenografts in immunocompromised ( SCID ) mice has provided a novel system in which to examine VZV neurotropism . - pubmed
Experimental infection with recombinant VZV mutants with targeted deletions or mutations of specific genes or regulatory elements provides an opportunity to assess gene candidates that may mediate neurotropism and neurovirulence . - pubmed
The SCID mouse - human DRG xenograft model may aid in the development of clinical strategies in the management of herpes zoster as well as in the development of " second generation " neuroattenuated vaccines . - pubmed
Endogenous adenosine is released in asthmatic patients ' lungs by inhaled allergen , however , its exact role in asthmatic responses or the receptors mediating these responses has not been determined . - pubmed
PURPOSE : To develop a standardized clinical grading system for the management of patients with vernal keratoconjunctivitis ( VKC ) and to identify the risk factors associated with a worsened outcome of the disease , including decrease of visual acuity and ocular complications development . - pubmed
PARTICIPANTS : A total of 207 consecutive patients with VKC , referred to our Cornea and External Diseases Center from 1997 to 2007 , were included in the study . - pubmed
The number of relapses and number of patients with decreased visual acuity were also evaluated in the follow - up . - pubmed
Sixteen patients were classified as grade 0 ( absence of symptoms and no therapy ) ; 59 patients were classified as grade 1 ( presence of symptoms without photophobia , occasional use of anti - allergic eye drop ) ; 74 patients were classified as grade 2 ( presence of symptoms including photophobia , daily anti - allergic treatment ) ; 22 patients with superficial punctuate keratopathy ( SPK ) were classified as grade 3 ( daily anti - allergic treatment associated with occasional topical steroid ) ; and 36 patients were classified as grade 4 ( diffuse SPK or corneal ulcer ; pulsed high - dose topical steroid ) . - pubmed
Scanning electron microscopic study of trophozoite and cyst stages of Naegleria fowleri . - pubmed
Whole trophozoites and cysts of axenically cultivated Naegleria fowleri were prepared for study of their surface morphology by scanning electron microscopy ( SEM ) . - pubmed
METHODS : We performed BBDIR on 20 control subjects and 13 patients with acute ischemic stroke . - pubmed
Suspicious intraplaque hemorrhage and calcification was demonstrated in 3 patients by CTI . - pubmed
The in vivo anti - inflammatory properties of CRBM-0244 were also investigated in a guinea pig model of allergic asthma . - pubmed
Together , these findings provide key evidence regarding the mode of action of CRBM-0244 in the lung , and point to new therapeutic strategies for modulating inflammation in patients with asthma . - pubmed
It then characterizes those chemicals using a chemical hazard - based framework that addresses persistence and bioaccumulation , human toxicity , and human exposures . - pubmed
We present a model for ceratomyxosis - induced mortality in O. - pubmed
The concern that endemically old and unique Australian vertebrate fauna might display high sensitivity to pesticides used for locust control provoked examination of the acute oral toxicity of the organophosphorus pesticide fenitrothion for the fat - tailed dunnart , Sminthopsis crassicaudata ( Gould 1844 ) , and the stripe - faced dunnart , S. - pubmed
By using the up - and - down method for determining acute oral toxicity , S. - pubmed
Patients were stratified retrospectively into high- or low - risk groups according to risk factors for significant carotid stenosis and perioperative stroke : peripheral vascular disease ( PVD ) , carotid bruit , diabetes mellitus , age & gt;70 years and/or history of cerebrovascular disease . - pubmed
CONCLUSION : In our cohort , selective screening of patients aged & gt;70 years , with carotid bruit , a history of cerebrovascular disease , diabetes mellitus or PVD would have reduced the screening load by 40 % , with trivial impact on surgical management or neurological outcomes . - pubmed
Our study aimed to examine mental fatigue effects among 10 neurologically normal , athletically active students undergoing typical concussion testing . - pubmed
SIGNIFICANCE : Neurologically intact and athletically active college students demonstrate effects related to fatigue after undergoing a typical sports concussion assessment battery , including an increase in subjectively experienced fatigue , a decrease in cognitive task performance accuracy and associated modulations in EEG activity . - pubmed
One published randomized controlled trial ( RCT ) reported significant reductions of gonorrhoea ( Neisseria gonorrhoeae ) [ rate ratio ( RR ) 0.46 , 95 % confidence interval ( CI ) 0.31 - 0.68 ] and chlamydia ( Chlamydia trachomatis ) ( RR 0.38 , 95%CI 0.26 - 0.57 ) , but no effect on serologic syphilis ( RR 1.02 , 95%CI 0.54 - 1.95 ) . - pubmed
One observational study reported genital ulcer disease ( GUD ) declines in sex workers , and two reported impact among male client populations for N. - pubmed
Additional benefits may include impact on STI and HIV transmission at population level . - pubmed
Clinical course of children with HIV associated thrombocytopenia . - pubmed
RESULTS : 34 children ( 19.6 % ) out of 173 were found to have thrombocytopenia . - pubmed
After excluding three who had pancytopenia associated thrombocytopenia , records of 31 children ( 28 M , 3 F ) were further studied . - pubmed
Cytotoxic activities and anti - tumor - promoting effects of microbial transformation products of prenylated chalcones from Angelica keiskei . - pubmed
Furthermore , the metabolite 13 exhibited inhibitory effect on skin tumor promotion in an in vivo two - stage mouse skin carcinogenesis test based on 7,12 - dimethylbenz [ a ] anthracene ( DMBA ) as initiator , and with TPA as promoter . - pubmed
Thus , lack of therapeutic efficacy demands innovative treatment options for patients with advanced ACC . - pubmed
A significant reduction in tumor size was detectable in NCIh295 tumor - bearing mice after a single treatment with SSLD-1H7 ( 0.89 + -0.15 cm ; P=0.006 ) and a diminished efficacy for SSLD - PEG+ ( 1.01 + -0.19 cm ; P=0.04 ) in comparison with untreated controls ( 1.5 + -0.0 cm ) . - pubmed
We examined physiological biomarkers ( hemolymph lactate , glucose , and protein concentrations ) of hypoxic stress in the red swamp crayfish Procambarus clarkii from chronically hypoxic natural habitats and laboratory hypoxia experiments . - pubmed
clarkii to severe hypoxia ( 1 mg / l DO ) , moderate hypoxia ( 2 mg / l DO ) , or normoxic conditions ( control : DO>7.5 mg / l ) for 12 , 24 , and 48 h. P. - pubmed
These results suggest that elevated hemolymph lactate and glucose concentrations are responses to acute hypoxia in P. - pubmed
Plasma marker proteins associated with the progression of lung cancer in obese mice fed a high - fat diet . - pubmed
Interestingly , the protein abundances of ten proteins exhibited a synergistic effect when treated with HFD in tumor - bearing mice ( Group I ) . - pubmed
In SH patients , the mechanism of atherosclerosis may be attributed to the lipid abnormalities . - pubmed
METHOD : The study enrolled 25 cases with SH and 20 healthy controls . - pubmed
Characteristics of patients with unilateral and bilateral Meniere ' s disease . - pubmed
OBJECTIVE : To evaluate epidemiologic differences between patients with unilateral and bilateral Meniere ' s disease ( MD ) . - pubmed
To delineate findings that might have implications as to the cause of MD , we have studied rigidly selected patient populations with unilateral and bilateral MD STUDY DESIGN : Prospective cohort . - pubmed
MATERIALS AND METHODS : Patients with a potential diagnosis of MD underwent extensive evaluations ( audiometric , radiologic , and immunologic ) , and only patients with idiopathic MD were included in this study . - pubmed
CONCLUSION : Patients with bilateral MD have a higher incidence of migraines and of a family history of MD . - pubmed
Because it is a non - invasive and cost - effective method to measure and analyze hemodynamics , it would bring to physiologists very important diagnostic information for the continuous care of critical patients with hemodynamic disorders . - pubmed
The role of the intestinal microbiota as a regulator of autoimmune diabetes in animal models is well - established , but data on human type 1 diabetes are tentative and based on studies including only a few study subjects . - pubmed
Reduced oestrogen levels in women during the menopausal transition may therefore increase their risk of hypertension and/or RAS - mediated changes to cerebrovascular or AD pathology . - pubmed
Macrophage depletion impairs corneal wound healing after autologous transplantation in mice . - pubmed
METHODS : Autologous corneal transplantation model was used to induce wound repair in Balb / c mice . - pubmed
Peritoneal macrophages were isolated from Balb / c mice and transfused into conjunctiva to examine the recovery role of macrophages depletion on wound healing after autologous corneal transplantation . - pubmed
We describe the case of a 33 - year - old man with a history of multiple minor head injuries observed to harbour asymptomatic , bilateral cerebrospinal fluid - density collections over the cerebellar hemispheres . - pubmed
The cysts partially recurred , necessitating reopening of the burrholes , after which the patient 's symptoms resolved entirely . - pubmed
A prolonged QTc syndrome was not uncommon in this cohort of asymptomatic HIV - infected patients with good immunovirological control . - pubmed
However , in vitro inhibitory activity against ten human tumor cell lines showed that hydrolyzed rutin exerted a more potent antiproliferative effect than quercetin and rutin on various cancer cell lines , specially glioma , and ovarian and breast adenocarcinomas . - pubmed
Pharmacokinetic analysis of piperacillin administered with tazobactam in critically ill , morbidly obese surgical patients . - pubmed
PATIENTS : Nine morbidly obese ( body mass index [ BMI ] 40.0 kg / m2 or higher ) hospitalized patients admitted to the trauma and surgical intensive care service who were treated with piperacillin - tazobactam between December 15 , 2010 , and April 18 , 2012 . - pubmed
About half of the world 's population is currently infected with Helicobacter pylori , which is involved in the development of several gastro - duodenal pathologies . - pubmed
The oral administration of piperine ( 1.12 mg / kg ) during 23 days in rats seemingly interfered with the toxicity of aflatoxins , decreasing hepatic injuries and the leukocyte depletion in experimentally intoxicated animals . - pubmed
Study population was composed of incident patients with advanced chronic kidney disease ( glomerular filtration rate & lt;30 mL / min ) related to type 2 diabetes in a tertiary hospital from Gran Canaria ( Spain ) during a period of 2 years . - pubmed
Of 78 eligible patients , 21.8 % had normoalbuminuria , 20.5 % had microalbuminuria , and 57.7 % had proteinuria . - pubmed
BACKGROUND : Cutaneous infection by Mycobacterium ulcerans , also known as Buruli ulcer ( BU ) , represents the third most common mycobacterial disease in the world after tuberculosis and leprosy . - pubmed
This is a prospective study including 40 patients with benign and malignant tumours of orbital , paraorbital and other sites giving rise to unilateral proptosis . - pubmed
Thus nasal obstruction is the commonest ENT presenting complains in these patients . - pubmed
Seasonal dynamics of Thelandros maplestonei infections in the wall lizard , Hemidactylus flaviviridis in Imphal Valley , Manipur , India . - pubmed
The influence of seasons on the population dynamics of the nematode , Thelandros maplestonei infection in Hemidactylus flaviviridis was studied for one annual cycle in the Imphal Valley , Manipur , India . - pubmed
maplestonei infections in H. - pubmed
Preclinical efficacy of melatonin in the amelioration of tenofovir nephrotoxicity by the attenuation of oxidative stress , nitrosative stress , and inflammation in rats . - pubmed
Identifying an agent that prevents tenofovir disoproxil fumarate ( TDF)-induced renal injury can lead to better tolerance to TDF , and a more effective treatment can be achieved in HIV infected patients . - pubmed
The present study is aimed at investigating whether melatonin , a potent antioxidant and anti - inflammatory agent , protects against TDF nephrotoxicity in rats . - pubmed
Some rats received 600 mg / kg body weight TDF by gavage for 35 days , while others received once daily 20 mg / kg body weight melatonin i.p . - pubmed
Results : Melatonin pretreatment protected the rats against TDF nephrotoxicity both histologically and biochemically . - pubmed
Conclusions : Melatonin pretreatment protects rats from tenofovir - induced damage to proximal tubular mitochondria by attenuating oxidative stress , nitrosative stress , and inflammation . - pubmed
This suggests that it may be useful in ameliorating TDF nephrotoxicity in humans . - pubmed
Impact of magnetic resonance imaging on computed tomography - based treatment planning and acute toxicity for prostate cancer patients treated with intensity modulated radiation therapy . - pubmed
PURPOSE : To evaluate rectal and bladder dosimetric and clinical acute toxicity endpoints for prostate patients treated with intensity modulated radiation therapy ( IMRT ) using magnetic resonance images ( MRI ) registered to computed tomographic ( CT ) simulation images versus CT alone . - pubmed
MATERIALS AND METHODS : The charts of 155 consecutive prostate cancer patients at our institution from 2004 to 2008 were reviewed . - pubmed
[ Effect of acupotomy intervention on cervicomuscular apoptosis in cervical spondylosis rabbits ] . - pubmed
Short daily versus conventional hemodialysis for hypertensive patients : a randomized cross - over study . - pubmed
BACKGROUND : Treatment of end stage renal disease patients with short daily hemodialysis has been associated with an improvement in blood pressure . - pubmed
STUDY DESIGN , SETTING AND PARTICIPANTS : We undertook a randomized cross - over trial in adult hypertensive patients with ESRD treated with conventional hemodialysis to determine : 1 ) if short - daily hemodialysis is associated with a reduction in systolic blood pressure after a 3 - month blood pressure optimization period and ; 2 ) the potential mechanism(s ) of blood pressure reduction . - pubmed
CONCLUSIONS : Patients treated with short daily , compared to conventional hemodialysis , have similar blood pressure control on fewer anti - hypertensive medications . - pubmed
The sensitivity of the different titles of antinuclear antibodies was determined in a group of 136 patients with a diagnosis of autoimmune rheumatic disease , and the specificity was determined in a group of 118 patients with other rheumatic diseases . - pubmed
Given that the bioactive lipid sphingosine 1 - phosphate is involved in cardiovascular pathophysiology , and since lipid accumulation and inflammation are hallmarks of calcific aortic stenosis , the role of sphingosine 1 - phosphate on the pro - inflammatory / pro - osteogenic pathways in human interstitial cells from aortic and pulmonary valves was investigated . - pubmed
Liberian man being treated for Ebola in Texas dies . - pubmed
Thus , the initiation of an international tumor registry may aid with the management of patients presenting with ACNs . - pubmed
Blastomycosis in a postpartum dog . - pubmed
Transplacental infection with Blastomyces dermatitidis is rare in humans and unknown in the dog . - pubmed
Brain abscess due to Trueperella bernardiae . - pubmed
We present the case of a brain abscess caused by a combination of rare organisms ( Trueperella bernardiae and Peptoniphilus harei ) in a patient with chronic suppurative otitis media that had been complicated by the presence of a cholesteatoma . - pubmed
All patients received tacrolimus ( dose , 0.1 mg / kg / body weight , in 2 divided doses ) . - pubmed
These four patients were all adolescents or young adults ( age 13 - 22 years ) , experienced preceding gastrointestinal symptoms , and had serological and/or bacterial evidence of recent Campylobacter jejuni enteritis . - pubmed
Patients were randomized to receive BST - CarGel treatment or microfracture alone , and followed standardized 12 - week rehabilitation . - pubmed
RESULTS : Blinded MRI analysis demonstrated that BST - CarGel -treated patients showed a significantly greater treatment effect for lesion filling ( P = 0.017 ) over 5 years compared with microfracture alone . - pubmed
A 80 - year - old male patient admitted to the emergency department with gross hematuria / clot retention and right flank pain . - pubmed
METHODS : In the present study , a consecutive sample of suspected patients with CAP was underwent CUS , CXR , and chest computed tomography ( CT ) scan . - pubmed
RESULTS : 30 patients with CAP were enrolled ( 93.3 % male with mean age of 63.8 + - 18.3 years ) . - pubmed
Magnesium sulphate can prolong pregnancy in patients with severe early - onset preeclampsia . - pubmed
OBJECTIVE : To assess whether long - term use of magnesium sulphate prolongs pregnancy in patients with severe early - onset preeclampsia . - pubmed
RESULTS : Long - term group showed significant prolongation of pregnancy compared with the control group ( 9.2 + - 7.9 versus 16.6 + - 9.3 d , log - rank test , p = 0.021 ) , which was also observed in patients with severe preeclampsia occurring before 28 weeks ' gestation ( n = 11 , 4.5 + - 5.2 versus 13.2 + - 6.8 d , log - rank test , p = 0.035 ) . - pubmed
CONCLUSIONS : Long - term use of magnesium sulphate prolonged pregnancy in patients with severe early - onset preeclampsia and can help alleviate progression of preeclampsia . - pubmed
ED TREATMENT : in n.18/182 subjects ( 9.9 % ) there was a concomitant hypotestosteronemia ; these patients were treated only with testosterone replacement ; this treatment was efficacious ( IIEF-5 total score & gt;=22 ) in 8/18 subjects ( 44.4 % ) . - pubmed
Retraction Note : Central macular thickness in patients with type 2 diabetes mellitus without clinical retinopathy . - pubmed
Hunter syndrome is generally considered to have two manifestations : an attenuated form and a severe form ; in the latter , the person has pronounced cognitive decline . - pubmed
Children with the severe phenotype show developmental delay and changes in behaviour patterns at about 18 months to 4 years of age . - pubmed
We studied the pharmacokinetics and efficacy of the broad - spectrum triazole isavuconazole for the treatment of experimental invasive pulmonary aspergillosis ( IPA ) in persistently neutropenic rabbits . - pubmed
There were significant concentration - dependent reductions of residual fungal burden ( log CFU / gram ) and of organism - mediated pulmonary injury , lung weights , and pulmonary infarct scores in ISA40- and ISA60 - treated rabbits in comparison to those of UC ( P & lt ; 0.001 ) . - pubmed
delta - CNTX - Pn1a does not cause any apparent toxicity to mice , when intracerebroventricularly injected ( 30 mug ) . - pubmed
In this study , we evaluated the antinociceptive effect of delta - CNTX - Pn1a in three animal pain models and investigated its mechanism of action in acute pain . - pubmed
In the inflammatory pain model , induced by carrageenan , delta - CNTX - Pn1a restored the nociceptive threshold of rats , when intraplantarly injected , 2 h and 30 min after carrageenan administration . - pubmed
Dengue is the most prevalent arboviral disease in humans and a major public health problem worldwide . - pubmed
RESULTS : Partnerships for maternal history of low birth weight ( OR : 41.1 ; 95 % CI : 5.5 - 306.7 ) were found ; prematurity ( OR : 12.0 ; 95 % CI : 1.5 - 94.3 ) , history of eclampsia ( OR : 5.8 ; 95 % CI : 1.9 - 17.4 ) , one to three prenatal controls ( OR : 5.7 ; 95 % CI : 2.6 - 12.3 ) , multiple gestation ( OR : 4.7 ; 95 % CI : 1.3 - 17.0 ) and tobacco consumption ( OR : 3.8 ; 95 % CI : 1.5 - 9.8 ) , not being a teenager ( OR : 0.3 ; 95 % CI : 0.1 - 0.6 ) , and not having a short birth interval ( OR : 0.2 ; 95 % CI : 0.1 - 0.7 ) . - pubmed
Sixty - eight Dutch FA patients have been transplanted since 1972 . - pubmed
OBJECTIVE : Case report of a patient with angioid streaks , peau d'orange , comet tail lesions , choroidal neovascularisation and presumed pseudoxanthoma elasticum ( PXE ) . - pubmed
One hundred patients had distant metastases , of which the liver was the only location in 54 patients . - pubmed
Overall survival rates for CRC patients with liver metastases who underwent resection were 30 % at 2 years and 17 % at 5 years , and the mean survival rate was 1.4 years . - pubmed
CONCLUSIONS : Both the mean survival rate of our CRC patients with resectable liver metastases and the 5 - year survival rate of these patients are lower than global averages . - pubmed
LLC animals were allowed to develop tumors for 4 wk to induce cachexia . - pubmed
This study aimed to determine whether genetic polymorphisms of genes in the vitamin D pathway are associated with treatment responses to pegylated interferon ( PEG - IFN)-based therapy in patients with chronic HCV infection . - pubmed
The innate immunity of guinea pigs against highly pathogenic avian influenza virus infection . - pubmed
In contrast to the highly virulent phenotype of H5N1 in humans and many animal models , guinea pigs do not typically display signs of severe disease in response to H5N1 virus infection . - pubmed
Furthermore , we show that guinea pig complement is involved in viral clearance , the regulation of inflammation , and cellular apoptosis during influenza virus infection of guinea pigs . - pubmed
This work uncovers features of the guinea pig innate immune response to influenza that may render guinea pigs resistant to highly pathogenic influenza viruses . - pubmed
METHODS : RADG was performed in patients with clinical Stage I gastric cancer , and reconstruction was performed using Delta . - pubmed
CONCLUSION : Cystic brain destruction might occur prenatally and neurodevelopment of gyration and differentiation of the cortical layers in the developing brain could be affected by sulfite accumulation early during the second trimester in ISOD patients . - pubmed
RESULTS : CB ( n = 264 ) compared to C ( n = 109 ) patients were younger , less likely performance status ( PS ) impaired , and more likely with liver metastases . - pubmed
For patients with right- vs. left - sided tumors , C ( but not CB)-treated patients had higher adjusted risk for progression ( HR = 1.715 , 95 % CI 1.108 , 2.653 ; p = 0.015 ) . - pubmed
Patients with right - sided tumors treated with C were at higher risk for disease progression than patients with left - sided tumors . - pubmed
Accordingly , in this study , we established an inflammatory bowel disease visceral pain model in rat by enema with a mixed solution of 5 % trinitrobenzenesulfonic acid and 50 % ethanol . - pubmed
Patients and methods : Patients undergoing cataract extraction and lens replacement ( CELR ) were eligible . - pubmed
Post - thrombotic syndrome ( PTS ) is the most common long - term complication after deep vein thrombosis ( DVT ) developing in up to 70 % of the patients . - pubmed
Methods : We performed a retrospective review of 47 patients performed single level posterior cervical laminoforaminotomy for cervical radiculopathy between 2004 and 2012 . - pubmed
We divided these patients into two groups , Group A : 27 patients for ruptured disc and Group B : 20 patients for foraminal stenosis and analyzed the demographic factors , amount of medial facetectomy , postoperative instability with neck pain and clinical outcomes . - pubmed
Thirteen patients complained of postoperative neck pain for 2 months . - pubmed
Edible fungal strains of Ascomycota ( Aspergillus oryzae , Fusarium venenatum , Monascus purpureus , Neurospora intermedia ) and Zygomycota ( Rhizopus oryzae ) phyla were screened and selected for their protein production yield . - pubmed
The appropriate target blood pressure ( BP ) in elderly patients with hypertension remains uncertain . - pubmed
The incidence of adverse drug reactions related to excessive BP lowering was lower in patients & lt;75 years than in patients & gt;=75 years ( 0.73 vs 1.02 % , P = 0.0461 ) . - pubmed
Our laboratory has previously reported DIAm sarcopenia in rats and mice characterized by DIAm atrophy and a reduction in maximum specific force at 24 months of age . - pubmed
The purpose of this study in Fischer 344 rats was to evaluate if there are sex - related differences in DIAm sarcopenia , and if such differences translate to a functional impact on Pdi generation across motor behaviors and maximal Pdi ( Pdimax ) elicited by bilateral phrenic nerve stimulation . - pubmed
In both males and females , DIAm sarcopenia was apparent in 24 - month - old rats with a ~30 % reduction in both maximum specific force and the cross - sectional area of type IIx and/or IIb fibers . - pubmed
MATERIALS AND METHODS : A prospective study was carried out on forty eyes of patients having signs and symptoms of dry eye . - pubmed
Patients were evaluated on the basis of dry eye - related symptom score , tear film break - up time ( TFBUT ) , tear meniscus height , fluorescein ocular surface staining score ( FOSS ) , and the Schirmer 's test at the end of 2 , 4 , 6 , and 12 weeks and their values were compared with the baseline . - pubmed
CONCLUSION : Nearly 2 % rebamipide ophthalmic solution provided relief in the symptoms of patients having dry eyes . - pubmed
The present study explores treatment outcomes for DRG subjects who were paresthesia - free vs. those who experienced the sensation of paresthesia , as well as the factors that predicted paresthesia - free analgesia . - pubmed
Outcomes of subjects who were paresthesia - free were compared to those who experienced paresthesia - present therapy at 1 , 3 , 6 , 9 , and 12 - month follow - ups . - pubmed
RESULTS : The percentage of subjects with paresthesia - free pain relief increased from 16.4 % at 1 - month to 38.3 % at 12 - months . - pubmed
Paresthesia - free subjects generally had similar or better outcomes for pain severity , pain interference , quality of life , and mood state as subjects with paresthesia - present stimulation . - pubmed
CONCLUSIONS : Some DRG subjects achieved effective paresthesia - free analgesia in the ACCURATE trial . - pubmed
We hypothesized that resting - state functional connectivities of habenula would show differences in neuroanatomical correlates of the evaluative system ( prefrontal cortex , habenula ) of patients with GAD . - pubmed
We obtained 22 patients with GAD and 21 HCs , matched for gender , age , and years of education . - pubmed
Patients with GAD demonstrated enhanced connectivities in the bilateral premotor cortex , right ventrolateral prefrontal cortex , medial frontal cortex , as well as the left orbitofrontal cortex , and reduced connectivities in the left posterior cingulate cortex , and right pulvinar . - pubmed
The purpose of this study was to investigate the prevalence of SLD - resistant strains and its specific mutations in drug - resistant Mycobacterium tuberculosis clinical isolates , and to acknowledge the transmission pattern of SLD resistance strains in Hebei . - pubmed
These analyses characterized the relationships between risankizumab exposures and key efficacy and safety variables in Japanese patients with moderate - to - severe plaque psoriasis , GPP , or EP following treatment with 75 or 150 mg subcutaneous doses at weeks 0 , 4 , and every 12 weeks thereafter . - pubmed
METHODS : Risankizumab average plasma concentrations ( Cavg ) were correlated with probabilities of achieving efficacy end points ( PASI 75 , PASI 90 , PASI 100 , and sPGA 0/1 ) using data from Japanese patients ( N = 225 ) and non - Japanese patients ( N = 1678 ) with moderate - to - severe plaque psoriasis enrolled in global trials , or a Japan Phase 2/3 trial . - pubmed
CONCLUSIONS : Overall , risankizumab 150 mg maximized efficacy , including PASI 100 response , in Japanese patients with psoriasis with no apparent relationship between exposure and evaluated safety variables . - pubmed
Herein , we report a 36 - year male patient presenting with right - sided flank pain and microscopic hematuria . - pubmed
Methods : The clinical characteristics and relevant variables were retrospectively analyzed in a total of 270 NDMM patients diagnosed between November 2009 and May 2018 . - pubmed
Effects of voluntary and forced exercises on motor function recovery in intracerebral hemorrhage rats . - pubmed
Motor paralysis is a severe consequence of intracerebral hemorrhage ( ICH ) that reduces patient quality of life . - pubmed
Rehabilitation is beneficial for stroke patients . - pubmed
We aimed to clarify the effect of voluntary and forced exercises for functional recovery in ICH rats . - pubmed
OBJECTIVE : To explore the inhibitory effects and molecular mechanisms of nano - realgar on the migration , invasion and metastasis of mouse breast cancer cells . - pubmed
A murine breast cancer metastasis model was established , administered nano - realgar for 32 days and monitored for tumor growth and metastasis by an in vivo optical imaging system . - pubmed
Meanwhile , nano - realgar effectively suppressed the abilities of tumor growth , metastasis and angiogenesis in the murine breast cancer metastasis model in a time- and dose - dependent manner . - pubmed
In vivo combination therapy with PENAO and gefitinib was non - toxic to mice and significantly delayed tumour growth and prolonged survival . - pubmed
At 20 days after treatment , tumours from the combination treated mice were significantly smaller than those from untreated and single drug treated mice . - pubmed
With decreasing mortality rates , a higher number of patients are impacted by long - term neuropsychiatric sequelae , such as cognitive deficits , depression , anxiety , and sleep - wake disorders . - pubmed
Neurostimulants are centrally acting medications used to assist in restoring these neurotransmitter abnormalities and are pharmacologic options to ameliorate symptoms in post - TBI patients . - pubmed
Large , well - powered studies have not been performed to validate their use in patients with TBI , leaving uncertainty for these agents ' place in therapy . - pubmed
This review provides clinicians with a summary of the available literature on neurostimulants following TBI to guide appropriate usage to help improve patients ' symptoms and optimize safety . - pubmed
Cell growth was determined using nude - mouse transplanted tumor experiments . - pubmed
miR-141 - 3p was down - regulated in breast cancer specimens and could serve as an independent prognostic factor for predicting overall survival in breast cancer patients . - pubmed
In addition , overexpression of miR-141 - 3p could inhibit hypoxia - induced cell migration and impede human breast cancer MDA - MB-231 cell growth in vivo . - pubmed
Mortality of NSCLC patients increases with the development of a metastatic lesion compared to when the tumor is localized ; however , the exact mechanism for what causes NSCLC cells to metastasize in the context of environmental toxicant exposure has yet to be fully elucidated . - pubmed
The prognostic value of fQRSTa in patients with aortic stenosis undergoing surgical aortic valve replacement . - pubmed
BACKGROUND : Surgical aortic valve replacement ( sAVR ) is the ultimate therapy for severe aortic stenosis ( AS ) in suitable patients . - pubmed
In this study , we aimed to investigate the prognostic value of fQRSTa in patients with severe symptomatic AS undergoing sAVR . - pubmed
METHODS : A total of 372 patients with severe degenerative AS who underwent successful sAVR were included in this retrospective study . - pubmed
CONCLUSION : fQRSTa was related with poor prognosis in patients with AS undergoing sAVR . - pubmed
Here , using proteomic analysis of Drosophila larval midguts during degradation , we identify a group of proteins with peptidase activity , suggesting a role in autophagy - dependent cell death . - pubmed
Hemodynamic instability caused by hyperdynamic circulation , systemic fluid retention , infection , and bleeding is frequently observed postoperatively in severely cirrhotic patients . - pubmed
Preoperative optimization , including correction of coagulopathy and poor nutrition , is therefore crucial for minimizing the predictive postoperative complications in those patients . - pubmed
Recently , the model for end - stage liver disease ( MELD ) score has been gaining attention for its reliability in identifying patients at high risk for open heart surgery . - pubmed
We investigated the relationship between AD ( assessed by CMR ) and coronary artery disease ( CAD ) severity ( assessed by the SYNTAX score ) in patients with premature CAD . - pubmed
We recruited 125 patients with CAD confirmed by coronary angiography ( males were < 55 years old and females < 65 years old ) . - pubmed
We excluded patients with significant aortic disease or contraindications to CMR . - pubmed
The severity of CAD in young patients is associated with decreased AD , especially at the level of the AR . - pubmed
The main objective of this research was to study the impact of chemotherapy on the cognitive function of patients with locoregional breast cancer . - pubmed
Excessive vascular remodeling has been shown in hypertensive patients . - pubmed
In a mouse model of angiotensin II - induced hypertension , we show that aortas exhibit increased medial thickening , fibrosis , and features of EndMT . - pubmed
The symptoms associated with the syndrome can vary greatly from individual to individual and within the family . - pubmed
Rauwolfia and breast cancer . - pubmed
Pathogenesis of rat colon carcinomas induced by N - methyl - N - nitrosourea . - pubmed
Well - developed tumors from rats receiving MNU generally presented grossly as polyps ; histologically , as invasive adenocarcinomas that had not metastasized . - pubmed
These tumors resembled their human counterparts . - pubmed
Focal epithelial atypias were found in grossly normal mucosa both from rats that had not yet developed tumors and from tumor - bearing rats . - pubmed
It was concluded that most invasive carcinomas in this rat model originate in foci of epithelial atypia , which are found with increasing frequency in the flat mucosa during treatment with MNU , but that some carcinomas also arise from adenomatous epithelium . - pubmed
Testosterone concentrations in plasma of dairy cows with ovarian cysts . - pubmed
Testosterone in plasma was measured by radioimmunoassay in cows with ovarian cysts and in cows during the estrous cycle . - pubmed
Concentrations of testosterone in plasma ( 60.8 + /- 2.7 pg / ml ; mean + /- standard error ) in cows with ovarian cysts were variable but within the range in cows during the estrous cycle . - pubmed
In cows with ovarian cysts , concentrations of testosterone in plasma declined within 24 h following prostaglandin F2 alpha and tended to increase by 9 days following gonadotropin releasing hormone . - pubmed
Comparative tumor - inhibitory and anti - bacterial activity of soluble and particulate glucan . - pubmed
A soluble fraction of particulate glucan was prepared and evaluated for its anti - tumor and anti - bacterial activity . - pubmed
Survival data demonstrated that intravenous administration of soluble or particulate glucan prolonged survival of A / J and C57BL/6J mice with subcutaneous tumor implants . - pubmed
As regards to bacterial infections , soluble and particulate glucan decreased renal necrosis in S. - pubmed
However , accumulating evidence indicates that human gamma / delta+ T - cells frequently recognize bacterial ligands as well as certain tumor cells . - pubmed
Total repair for truncus arteriosus using an external conduit was performed in 12 patients from 1978 through 1989 . - pubmed
Replacement of an external conduit was performed due to a conduit stenosis in 2 children and 1 infant , 10 years and 2 months , 7 years and 9 months , and 1 year and 8 months after the total repair , respectively . - pubmed
16 children with atopic dermatitis and 4 nonatopics were skin tested with flavourings and perfumes . - pubmed
The preoperative MR studies of 25 patients with surgically proved medulloblastomas were retrospectively reviewed in order to characterize these neoplasms with regard to their MR signal intensity , size , location , and appearance after contrast enhancement . - pubmed
In the patients who received gadopentetate dimeglumine , the fraction of tumor volume showing enhancement was found to be less than one third in two cases , between one third and two thirds in four cases , and greater than two thirds in five cases . - pubmed
From January ' 81 to April ' 91 , one shot transarterial infusion therapy and transcatheter arterial embolization therapy were performed in five patients with recurrences of hepatocellular carcinomas after surgery . - pubmed
In a study of prognosis in node - negative breast carcinoma , we investigated 293 T2N0M0 patients treated by mastectomy and axillary dissection with a median follow - up of 19.8 years . - pubmed
Recurrence at 20 years was not significantly different for patients with invasive duct ( 34 % ) and lobular ( 42 % ) carcinoma . - pubmed
Women with special types ( medullary , mucinous , papillary , etc ) of carcinoma had a 25 % chance of recurrence . - pubmed
Subsequent contralateral breast carcinoma was diagnosed in 29 patients , and four of these were fatal , accounting for only 4.6 % of breast carcinoma deaths . - pubmed
Thirty - two patients ( 10.9 % ) developed a nonmammary malignant neoplasm ( NMMN ) after the ipsilateral breast carcinoma , and 69 % of these lesions were fatal . - pubmed
This is the first reported case of documented transmission of S pyogenes , causing a toxic shocklike syndrome in an emergency medical technician . - pubmed
The technique of total pelvic exenteration with simultaneous bowel and urinary reconstruction is described as a surgical option for the management of pelvic sarcoma in adults and for highly selected patients with other types of advanced pelvic malignancy . - pubmed
The surgical technique is presented in detail as performed in a 43 - year - old man who presented with extensive primitive pelvic sarcoma . - pubmed
In adult sows , ketamine induced profound analgesia , which was not obtained in young pigs ; this difference in potency could not be related to pharmacokinetic differences between young and adult swine. - pubmed
injection of fluorocitrate in mice resulted in seizures after an average latency of 15 s , while intracerebroventricular ( i.c.v . ) - pubmed
[ Hemodynamics of the greater and lesser circulation in patients with hypertension ] . - pubmed
Based on a study of the hemodynamics of the greater and pulmonary circulation by direct methods in 117 patients with essential hypertension it has been demonstrated that changes in the stroke volume are implicated in the mechanism of the interregulation of the greater and pulmonary circulation . - pubmed
The lesions , clinically and histopathologically , resemble lepromas which develop at the site of experimental inoculation of Mycobacterium leprae in armadillos . - pubmed
VFP goggles were used in the treatment of 7 patients with migraine headache . - pubmed
Of 50 migraine headaches recorded , 49 were rated by the patient as being helped and 36 as being stopped by using the VFP goggles . - pubmed
Treatment reduced the median duration of headache in all patients . - pubmed
A comparison of some effects of phosphine , hydrogen cyanide and anoxia in the lesser grain borer , Rhyzopertha dominica ( F. ) ( Coleoptera : Bostrychidae ) . - pubmed
The effects of phosphine , hydrogen cyanide and anoxia on levels of ATP , pyruvate and lactate in Rhyzopertha dominica are compared . - pubmed
Fusions were performed with or without prior transformation of PBL with Epstein - Barr virus ( EBV ) . - pubmed
It may reduce long - term mortality in patients with known coronary artery disease and may slow or reverse the progression of atherosclerosis . - pubmed
The beneficial effects , taken together with the low cost of nicotinic acid therapy and the relative freedom from serious side effects , have made nicotinic acid the agent of choice for the treatment of many patients with hyperlipidemia . - pubmed
In this report of 211 patients , malignant melanomas in BANS sites had a 4.6 % poorer 5 - year cumulative survival rate ( 88.9 % BANS , 93.5 % non - BANS ; p = 0.35 ) . - pubmed
Salmonella enteritidis bacteremia in childhood . - pubmed
We have reviewed the clinical course of 32 children with Salmonella enteritidis bacteremia and compared them with 135 children with acute gastroenteritis caused by S. - pubmed
A preoperative barium esophagogram and esophageal manometry in an adult patient with an H - type congenital tracheoesophageal fistula revealed the typical esophageal motor abnormalities previously described following operative repair of esophageal atresia in infants . - pubmed
The specificity of leishmaniasis I.H.A.T. in albino rats experimentally infected with Toxoplasma gondii and Hymenolepis nana . - pubmed
[ Leukodystrophy in children ] . - pubmed
Unilateral acute , fulminating renal papillary necrosis with Escherichia coli septicemia . - pubmed
The early effects of metabolic acidosis on renal metabolism in the rat . - pubmed
The early renal metabolic response was studied in rats made acidotic by oral feeding of ammonium chloride . - pubmed
Ammonia production by the same slices was also increased at 2 hr , but thereafter fell and at 6 hr had decreased to levels which , although higher than those of the control , were lower than those obtained from the rats acidotic for only 2 hr . - pubmed
There was no correlation between in vitro gluconeogenesis and ammonia production by kidney slices from rats during the first 6 hr of acidosis , but after 48 hr of ammonium chloride feeding , these two processes were significantly correlated . - pubmed
There was never any difference in pyruvate or lactate levels or lactate : pyruvate ratios between control and acidotic rats . - pubmed
Fifty - six patients with chronic allergic rhinitis were selected for a randomized double - blind study comparing oxatomide with a placebo . - pubmed
In a survey of 75 patients at 6 - 11 weeks gestation , fetomaternal hemorrhage ( FMH ) was detected by significant rises ( greater than 2 S.D. ) - pubmed
Hormonal and hemodynamic responses to vena caval obstruction in fetal sheep . - pubmed
This paper presents an alternative method of demarcating regions of interest over the myocardium after administration of 123I - heptadecanoic acid to patients with coronary artery disease . - pubmed
When 382 urine specimens were analysed by the modified test which is described in detail , there were neither false negatives nor false positives for infections with Escherichia , Klebsiella , Citrobacter or Proteus species . - pubmed
The efficacy and safety of bromocriptine mesylate ( 5 to 7.5 mg per day for up to 24 weeks ) were studied in 22 clinical trials involving 226 patients who had amenorrhea / galactorrhea associated with hyperprolactinemia and no demonstrable pituitary tumor . - pubmed
Galactorrhea was significantly ( at least 75 % ) reduced in 76 % of the 187 patients after an average treatment tome of 6.4 weeks , and was completely suppressed in 58 % after 12.7 weeks . - pubmed
Several patients experienced hypotension , but only 1 discontinued therapy because of it . - pubmed
Developmental changes of the hypogastric ganglion associated with the differentiation of the reproductive tracts in the mouse . - pubmed
In these animals , the hypogastric ganglion which is thought to innervate the internal genitalia was examined at birth . - pubmed
The number of ganglion cells was significantly larger in prenatally DES - exposed male and TP - exposed female mice than that of controls . - pubmed
The suppressive effect of PVA on the host defense to experimental infection with Escherichia coli was weaker than those of HB and BV . - pubmed
A very - low - calorie formula diet ( Cambridge diet ) for the treatment of diabetic - obese patients . - pubmed
Prolonged blockade of nitric oxide synthesis in gravid rats produces sustained hypertension , proteinuria , thrombocytopenia , and intrauterine growth retardation . - pubmed
OBJECTIVE : Our purpose was to test the hypothesis that chronic inhibition of nitric oxide synthesis in pregnant rats can produce a preeclampsia - like syndrome . - pubmed
CONCLUSION : Chronic inhibition of nitric oxide synthesis in gravid rats leads to sustained hypertension , proteinuria , thrombocytopenia , and intrauterine growth retardation , providing a simple animal model for preeclampsia . - pubmed
Mutatox is a new genotoxicity bioassay which uses as the endpoint the bioluminescence produced on reversion of a dark strain of the marine bacterium Vibrio fischeri + /- S9 . - pubmed
For screening , Mutatox provides many advantages over the Salmonella typhimurium ( Ames ) assay : it requires minimal sterility , employs a shorter incubation period , and does not require culture maintenance . - pubmed
For the purpose of this study , 1,107 electrocardiograms ( ECGs ) from patients who had undergone cardiac catheterization were used to train and test neural networks for the diagnosis of myocardial infarction . - pubmed
A twenty eight year - old man with anomalous pulmonary venous drainage from the right lung to the inferior vena cava ( scimitar syndrome ) underwent surgical treatment . - pubmed
Cytogenetic characterization of the human prostate cancer cell line P69SV40 T and its novel tumorigenic sublines M2182 and M15 . - pubmed
Cytogenetic studies of a SV40 T antigen immortalized human prostate epithelial cell line ( P69SV40 T ) and its increasingly tumorigenic tumor sublines , designated M2182 and M15 , were done with GTG - banding and multicolor fluorescence in situ hybridization ( FISH ) . - pubmed
Those unique to M15 were a der(16)t(16;19 ) and -Y. Chromosome imbalances resulting from numerical and/or structural abnormalities in the tumor sublines involved several chromosome regions that have previously been implicated in human prostate cancer , such as loss of Xp , Y , 3p ( M2182 and M15 ) , 16q ( M15 ) , and gains for 5q ( M2182 ) and 8q ( M2182 and M15 ) . - pubmed
Collectively , the characterization of these lines should assist with the localization of chromosome regions , and possibly genes , that are important in the development and progression of human prostate cancer . - pubmed
STUDY DESIGN : In this study the motor scores of 62 consecutive acute spinal cord - injured patients were retrospectively reviewed . - pubmed
METHODS : Sixty - two consecutive adult patients admitted within 7 days of acute spinal cord injury between April , 1983 , and September , 1992 , were evaluated . - pubmed
There were 38 patients with cervical and thoracic lesions , 12 patients with dorso - lumbar lesions , and 12 patients with lower lumbar lesions . - pubmed
BACKGROUND AND PURPOSE : Cerebral amyloid angiopathy ( CAA ) occurs as a sporadic disorder in aged humans , as a frequent component of Alzheimer ' s disease , or in hereditary cerebral hemorrhage with amyloidosis ( HCHWA ) . - pubmed
The primary histological locus of cerebral amyloid deposition varies in aged humans and in different species of nonhuman primates . - pubmed
In aged rhesus monkeys , amyloid deposition occurs most frequently in senile plaques , whereas in aged squirrel monkeys CAA is more common . - pubmed
These observations support the utilization of the monkeys as models to study CAA . - pubmed
The patient , a 31 year - old man , arrived to the hospital complaining of abdominal pain and vomiting , but then developed a clinical picture of low intestinal obstruction . - pubmed
Effect of steroid therapy on parameters of peripheral autonomic dysfunction in leprosy patients with acute neuritis . - pubmed
Recent electrophysiological studies on peripheral autonomic dysfunction in leprosy patients show a high prevalence of autonomic dysfunction as measured by abnormal vasomotor reflexes ( VMR ) and absent sympathetic skin response ( SSR ) . - pubmed
Since there is evidence that small fiber function may be the most reversible component in neuropathies , we measured the effect of steroid treatment on autonomic parameters together with motor and sensory functions in leprosy patients with acute neuritis . - pubmed
In this study , the authors examined PG ' s effects on the toxicity of ethanol in the primary culture of rat regenerations . - pubmed
Junctional rhythm occurred in 1 to 3 patients in all other groups with the exception of the Edr - Atr(1 ) group in which no cardiac arrhythmias occurred . - pubmed
CONCLUSIONS : On the basis of the present results , anticholinesterase - anticholinergic combinations should be avoided in patients having a long QT interval syndrome or a prolonged QT interval from other causes . - pubmed
Long - term treatment of chronic schizophrenia with risperidone : an open - label , multicenter study of 386 patients . - pubmed
An open - label , multicentre study was conducted to assess the long - term efficacy and safety of risperidone in patients with chronic schizophrenia . - pubmed
Extrapyramidal symptoms ( scores on the Extrapyramidal Symptom Rating Scale ) tended to decrease in severity or remained unchanged over the course of risperidone treatment ; 27.7 % of patients required antiparkinsonian medication during the study . - pubmed
An experiment was carried out with a Culex quinquefasciatus strain with resistance genes called " Quibu " , this strain was pressured with 3 organophosphorous insecticides : malathion , chlorpyriphos , and pyrimiphos - methyl . - pubmed
Although much is now known about the pathophysiology and biology of this parasite in the cat , the practical application and rapid development of this information to daily practice has led to confusion . - pubmed
A 16 - year - old boy presented with hypertension and sudden abdominal pain after minor blunt abdominal trauma . - pubmed
Pheo should be considered in hypertensive pediatric patients with a history of blunt abdominal trauma . - pubmed
Mycoplasma pneumoniae : a cause of coma in the absence of meningoencephalitis . - pubmed
That Mycoplasma pneumoniae encephalopathy can occur in the presence of a normal CSF examination is less well appreciated . - pubmed
The authors report two children who presented with coma and normal CSF findings in whom a diagnosis of acute Mycoplasma pneumoniae infection was made . - pubmed
Recent techniques in neurovascular bundle preservation could lead to an overall improvement in postoperative quality of life without compromising cancer control in the appropriately selected patient . - pubmed
Five patients with advanced HCC secondary to chronic hepatitis and cirrhosis underwent pretreatment and posttreatment MR examination on a 1.5 T MR scanner following systemic chemotherapy . - pubmed
Three of these patients had no or minimal change of tumor volume ; however , there was an increase in tumor necrosis in follow - up MR image . - pubmed
One patient of five with no change in tumor necrosis had no response and died at 3 months . - pubmed
Serial MR images showed increased irregular necrosis of advanced HCC after systemic chemotherapy , but stable volume , in patients who responded clinically to systemic chemotherapy . - pubmed
PATIENTS : Five alert , critically ill adults receiving mechanical ventilatory support . - pubmed
RESULTS : Logistic regression demonstrated that a murine blastocyst formation rate & gt;or=53.3 % in 50 % hydrosalpinx fluid ( OR = 16.6 , 95 % CI 2.4 - 116.1 , P = 0.005 ) and patient age ( OR = 0.778 , 95 % CI 0.61 - 0.99 , P = 0.045 ) were independent predictors of IVF outcome . - pubmed
More information is needed on late toxicity that influences the quality of life for these patients . - pubmed
pylori resulted in complete endoscopic and histological remission of MALT - lymphoma in 9 out of 10 patients as assessed 6 months after this eradication . - pubmed
A 15 - year - old girl presented with a history of cough , fever for five months and breathlessness of two days duration . - pubmed
[ Slow , chronic , organic and functional adrenal insufficiencies in the child ] . - pubmed
[ On experimental ethylene glycol renal lithiasis in the male and female rat ] . - pubmed
Oxygen is the first treatment the patient needs in order to overcome hypoxemia . - pubmed
With the exception of hypoxemic patients who also need oxygen , the administration of beta-2 agonists using metered - dose inhalers with a holding chamber was found to be as effective as administration with nebulizers , and in some studies , even more effective and safer . - pubmed
With the exception of the most severe asthma attacks , high - dose inhaled corticosteroids are at least as effective as oral corticosteroids in controlling moderate - to - severe asthma attacks especially in children . - pubmed
METHODS : Adenoid tissue cells from 13 atopic and 8 non - atopic children were cultured and stimulated with ionomycin and 4beta - phorbol 12 - myristate 13 - acetate . - pubmed
Atrial fibrillation affects approximately 2 million people in the United States and is a common comorbidity among patients with heart failure . - pubmed
Clinical studies indicate that the benefits of the beta - blocker carvedilol in patients with heart failure extend to patients with heart failure complicated by atrial fibrillation . - pubmed
The results of the Carvedilol in Atrial Fibrillation Evaluation ( CAFE ) trial provide support that carvedilol has incremental benefit when added to digoxin for the management of atrial fibrillation in patients with heart failure . - pubmed
Additional recent studies suggest that carvedilol may be useful in managing postsurgical atrial fibrillation and also may prevent recurrence of atrial fibrillation among patients who undergo cardioversion . - pubmed
In an effort to examine the utility of the metabonomic approach for discriminating sera from women with EOC from healthy controls , we performed ( 1 ) H - NMR spectroscopic analysis on preoperative serum specimens obtained from 38 patients with EOC , 12 patients with benign ovarian cysts and 53 healthy women . - pubmed
In addition , we analyzed the regions of NMR spectra that most strongly influence separation of sera of EOC patients from healthy controls . - pubmed
CONCLUSIONS : Postoperative adjuvant therapy with edrecolomab restores the in vivo deficient immune responses of patients with resected Dukes ' C CRC despite its clinical ineffectiveness in recent randomized adjuvant trials . - pubmed
BACKGROUND : Oral warts , caused by human papillomavirus ( HPV ) , and oral hairy leukoplakia ( OHL ) caused by Epstein - Barr virus ( EBV ) , are common oral manifestations in HIV - infected persons . - pubmed
METHODS : Biopsies were taken from lesion - positive and adjacent lesion - negative sites of HIV+ persons with oral warts or OHL and lesion - negative sites from HIV+ persons who were oral HPV or EBV DNA - positive ( matched controls ) . - pubmed
Legionella pneumophila is an important opportunistic pulmonary pathogen that causes Legionaires'diseases . - pubmed
An understanding of these roles will inform studies of their contribution to fertility and infertility in man . - pubmed
Living donor liver transplantation ( LDLT ) has become a well - recognized treatment modality for patients with end - stage liver disease . - pubmed
Hepatic arterial thrombosis was encountered in 3 patients . - pubmed
This has increased liver transplantations in the presence of limited cadaver grafts and has decreased the patient mortality in the waiting list . - pubmed
A 76 - year - old woman with a history of total thyroidectomy for a thyroid carcinoma at the age of 63 was admitted to our hospital for the treatment of a renal rupture induced by a tumor of about 3 cm in diameter . - pubmed
Adult mice were ovariectomized as models of experimental osteoporosis . - pubmed
This third section focus on those drugs used to treat mycobacterial infections ( Mycobacterium tuberculosis ) , fungal infections ( Candida species , Aspergillus species ) , and viral infections ( herpes , hepatitis , and influenza ) . - pubmed
We studied 164 patients with Peyronie ' s disease , 34 of whom have clinical symptoms of erectile dysfunction . - pubmed
Dopplerographic signs of venoocclusive dysfunction were seen also in patients with minor erectile disorders ( 55.4 % ) . - pubmed
Calendar period and age at HIV seroconversion strongly influenced AIDS and death rates . - pubmed
In 33 patients ( 53 % ) some other pelvic prolapse was corrected . - pubmed
In the last revision , 58 patients ( 93 % ) proved to be objectively continent and 4 ( 6.5 % ) showed a notable improvement in their incontinence . - pubmed
A dystocia and caesarean section model to characterize uteroplacental prostaglandin concentrations associated with retained placenta in dairy cattle . - pubmed
METHODS : Between 1995 and 2002 , three women and one man aged from 13 to 58 years were treated for chylothorax after thoracic surgery . - pubmed
RESULTS : These patients had : a pulmonary and hepatic cystectomies , a resection of the mediastinal tumor , an Akyama oesophagectomy and a resection of four left pulmonary metastases . - pubmed
In the patient who had had an oesophagectomy , chylothorax persisted after re - operation . - pubmed
Tamarix gallica , a hepatic stimulant and tonic , was examined for its ability to inhibit thioacetamide ( TAA)-induced hepatic oxidative stress , toxicity and early tumor promotion response in male Wistar rats . - pubmed
Pretreatment of rats orally with Tamarix gallica extract ( 25 and 50 mg / kg body weight ) prevented TAA - promoted oxidative stress and toxicity . - pubmed
Our data suggests that Tamarix gallica is a potent chemopreventive agent and may suppress TAA - mediated hepatic oxidative stress , toxicity , and tumor promotion response in rats . - pubmed
Endometrial damage and apoptosis in rats induced by dichlorvos and ameliorating effect of antioxidant vitamins E and C. - pubmed
We aimed to investigate the effect of subchronic administration of dichlorvos ( DDVP ) on endometrium and to evaluate ameliorating effects of a combination of Vitamins E and C against DDVP toxicity in the rat . - pubmed
Clinical utility of " blind placement " prostatic stent in patients with benign prostatic obstruction : a prospective study . - pubmed
OBJECTIVES : To assess the efficacy and safety of two versions of a blind placement temporary prostatic stent in the treatment of patients with benign prostatic obstruction . - pubmed
METHODS : Tissue samples from 110 patients with GERD ( n = 43 ) , BE ( n = 20 ) , and BC ( n = 47 ) were obtained in routine upper GI endoscopy . - pubmed
OBJECTIVE : To understand the role of epilepsy surgery in children with generalized or bilateral findings on preoperative scalp EEG . - pubmed
METHODS : From our pediatric epilepsy surgery series , we identified 50 patients in whom 30 to 100 % of preoperative epileptiform discharges ( ictal , interictal , or both ) were generalized or contralateral to the side of surgery . - pubmed
RESULTS : All patients had severe refractory epilepsy and an epileptogenic lesion on brain MRI . - pubmed
At last follow - up ( median 24.0 months ) , 72 % of patients were seizure - free , 16 % had marked improvement with only brief episodes of staring or tonic stiffening , and 12 % were not improved . - pubmed
Postoperative seizure - free rate did not differ from that in a comparison group of similar patients who matched the study group except for their high percentage ( 70 to 100 % ) of ipsilateral ictal and interictal epileptiform discharges on preoperative EEG . - pubmed
CONCLUSIONS : Epilepsy surgery may be successful for selected children and adolescents with a congenital or early - acquired brain lesion , despite abundant generalized or bilateral epileptiform discharges on EEG . - pubmed
Tilarginine in patients with acute myocardial infarction and cardiogenic shock . - pubmed
OBJECTIVE : To determine whether the presence of tumour at a free serosal surface was independently associated with pelvic recurrence or survival in patients who had a resection for clinicopathological stage B or stage C rectal cancer and who had not received adjuvant therapy . - pubmed
RESULTS : In 665 patients with stages B or C tumour , 35 ( 5.3 % ; CI 3.7 - 7.2 % ) had tumour at a free serosal surface . - pubmed
Adjuvant therapy for premenopausal patients with early breast cancer . - pubmed
PURPOSE OF REVIEW : Current topics on adjuvant therapy for premenopausal patients with breast cancer are reviewed . - pubmed
RECENT FINDINGS : The Early Breast Cancer Trialists ' Collaborative Group overview showed that women under 50 received a remarkable benefit from postoperative chemotherapy and endocrine therapy . - pubmed
The impact of chemotherapy - induced amenorrhea on patient outcome remains to be defined . - pubmed
SUMMARY : There are a number of unresolved issues in terms of the optimal use of chemotherapy and endocrine therapy in premenopausal patients with breast cancer . - pubmed
We examined the hypotheses that elderly individuals with GAD will have elevated salivary cortisol levels compared to nonanxious subjects , and that elevated cortisol levels in GAD will be associated with measures of symptom severity . - pubmed
The Effect of Cromolyn Sodium and Nedocromil Sodium Administered by A pressurized Aerosol with A spacer Device on Exercise - Induced Asthma in Children . - pubmed
BACKGROUND : The ability of risedronate to prevent and/or treat orchidectomy - induced osteoporosis in male rats was studied . - pubmed
BACKGROUND : Human bocavirus ( HBoV ) can be found in a substantial proportion of children with respiratory tract diseases . - pubmed
The relative importance of HBoV in viral respiratory tract illnesses is not yet well known . - pubmed
OBJECTIVE : In this study , we looked for HBoV in pediatric patients to determine the incidence of HBoV as single infection and compared it with other commonly found respiratory viruses to describe the clinical differences associated with HBoV infections in children . - pubmed
We studied the frequency of HBoV and 15 other respiratory viruses in nasopharyngeal aspirates and compared the clinical course of the infections caused by HBoV with those caused by other common respiratory viruses . - pubmed
Clinical differences were observed between HBoV and respiratory syncytial virus ( RSV ) infections ( children were older and bronchiolitis less frequent ) , adenovirus ( fever less frequent in HBoV group ) , and rhinovirus - associated infections ( less hypoxia in HBoV group ) . - pubmed
CONCLUSIONS : HBoV was the fourth most frequent single virus after RSV , rhinovirus , and adenovirus in children hospitalized because of respiratory infection . - pubmed
METHODS : We measured the heart rate and affect of 17 adolescent recovering anorexic patients and 40 healthy age - matched controls during two conditions of the Stress Induced Speech Task ( SIST ): Free Association and Stress Task . - pubmed
DISCUSSION : Although the physiological stress response of recovering adolescent anorexic patients was similar to controls , the psychological response of partially and fully weight - restored anorexic adolescents appears similar to that of acutely anorexic adolescents . - pubmed
One major complication occurred ( 5.8 % ): perforation of the hepaticojejunostomy in a patient with recurrent choledocolithiasis , which was successfully resolved surgically . - pubmed
Inhibiting glycosphingolipid synthesis ameliorates hepatic steatosis in obese mice . - pubmed
SUBJECT : A 67 - year - old male with intractable back pain due to advanced lumbar spondylosis , with a history of advanced Parkinson ' s Disease requiring two deep brain stimulators . - pubmed
CONCLUSIONS : Intravitreal triamcinolone is superior to observation for treating vision loss associated with macular edema secondary to CRVO in patients who have characteristics similar to those in the SCORE - CRVO trial . - pubmed
Although this patient had normal plain films and computed tomography of the spine , her disease was first visualized by magnetic resonance imaging . - pubmed
The multitude of publications leads to an evident and consistent conclusion : breasts reconstructed with an overly long vertical incision all suffer the same deformity characterized by a banana or squash - shaped breast . - pubmed
Studies in the preclinical animal models of arthritis as well as RA were examined critically and the data are presented . - pubmed
RESULTS : Most of the single nucleotide polymorphisms ( SNPs ) showed no significant interaction with E coli exposure for both eczema and allergic sensitization . - pubmed
We present the case of a woman born with transposition of the great arteries , who was surgically repaired with the Mustard technique . - pubmed
BACKGROUND : Severe outcomes have been described for both Plasmodium falciparum and P. - pubmed
Thoracic vertebral cavernous hemangioma in a schizophrenic patient -- case report . - pubmed
A 55 - year - old man presented with gait disturbance , incontinence , and back pain . - pubmed
Schizophrenic patients have diminished sensitivity to pain or other symptoms , so neurological symptoms may become severe . - pubmed
The patient had a rare association of vertebral hemangioma and hepatic hemangioma , which may be a chance occurrence . - pubmed
Pancreatitis and cholangitis due to cytomegalovirus in a patient with hyperimmunoglobulin E syndrome . - pubmed
Twenty - eight ( 21 F ; 7 M ; mean age 34.2 + - 8.2 ) migraine and 15 ( 11 F ; 4 M ; mean age 35.9 + - 8.9 ) healthy subjects were recruited in a double - blind , placebo - controlled , cross - over trial . - pubmed
Furthermore , in migraineurs who developed migraine after GTN , a significant facilitation in temporal summation of pain was detected 60 ' , 120 ' and 180 ' after drug intake when compared to patients without clinical response . - pubmed
In migraineurs the susceptibility to develop migraine attack after GTN administration seems to be a specific trait of a subgroup of patients linked to a supersensitivity of the pain system to GTN . - pubmed
MATERIALS AND METHODS : We prospectively examined 77 thyroid nodules in 60 patients undergoing ultrasound - guided fine needle aspiration biopsy ( FNAB ) . - pubmed
The value of 99mTc - tetrofosmin brain SPECT in predicting survival in patients with glioblastoma multiforme . - pubmed
In the present study , we set out to investigate the prognostic value of ( 99m ) Tc - tetrofosmin brain SPECT in patients with glioblastoma multiforme . - pubmed
METHODS : We prospectively studied 18 patients ( 13 men , 5 women ; mean age + - SD , 60.8 + - 7.79 y ) who were operated on for glioblastoma multiforme . - pubmed
Although patients with near - total tumor resection who were younger than 60 y survived longer , the difference did not reach statistical significance . - pubmed
CONCLUSION : ( 99m ) Tc - tetrofosmin brain SPECT may be an independent prognostic factor in patients with glioblastoma multiforme . - pubmed
Macrophage depression ( injection of gadolinium chloride associated with a decrease in metastasis number ) decreased serum concentration of tissue inhibitor , but it did not attain the control level observed in intact mice . - pubmed
Thirty nine intrabony defects in 21 patients were treated with Fortoss Vital ( Biocomposites , Staffordshire , UK ) . - pubmed
Syringohydromyelia in horses : 3 cases . - pubmed
The presenting complaints , clinical , gross pathological , and histopathologic findings of 2 cases of syringomyelia and 1 case of hydromyelia in horses are described . - pubmed
METHODS : We undertook a retrospective review of all patients undergoing endoluminal stenting for CD strictures at our institution from 2001 to 2010 . - pubmed
CONCLUSIONS : Endoluminal stenting of CD strictures is a safe and effective alternative to surgery which can provide lasting benefit in select patients . - pubmed
Chiropractic management of a 40 - year - old female patient with Meniere disease . - pubmed
OBJECTIVE : The purpose of this case report is to describe the chiropractic management of a patient with Meniere disease . - pubmed
CLINICAL FEATURES : A 40 - year - old woman presented with a diagnosis of Meniere disease including a 2 - month history of vertigo and a 16 - month history of left - sided tinnitus , low - frequency hearing loss , and aural fullness . - pubmed
The patient 's other symptoms included left - sided neck pain , temporomandibular joint pain , and headaches . - pubmed
Within 2 weeks of treatment , the patient 's tinnitus had resolved ; and all other symptoms ( including vertigo ) were improved . - pubmed
The patient 's headaches , neck pain , and vertigo were subsequently resolved within 3 months of treatment . - pubmed
CONCLUSION : This case report suggests that chiropractic care , including upper cervical spinal manipulation and soft - tissue therapy , may be beneficial in treating some patients with Meniere disease . - pubmed
The impact of cardiac resynchronization therapy in an end - stage heart failure patient with a left ventricular assist device as a bridge to recovery . - pubmed
METHODS : Groups of rats were defined by the presence of inflammation , surgical intervention , and/or the type of general anesthetic used for a 3 - h period of anesthesia . - pubmed
What are the options for anticoagulation needs in dialysis for patients with heparin - induced thrombocytopenia ? - pubmed
However , here we report the cases of two children with congenital cholesteatoma which disappeared spontaneously during the follow - up period . - pubmed
We report the case of a 61 - year - old man with an angiosarcoma of the carotid artery . - pubmed
Antibacterial activity was evaluated against that of reference strains of Staphylococcus aureus , Staphylococcus epidermidis , Streptococcus pneumoniae , Escherichia coli and Pseudomonas aeruginosa . - pubmed
Enteric disease in dogs naturally infected by a novel canine astrovirus . - pubmed
Infection by a novel canine astrovirus was associated with gastroenteritis in two dogs . - pubmed
We report the successful management of a female patient who developed postoperative thrombotic thrombocytopenic purpura ( TTP ) after an uneventful laparoscopic oophorocystectomy . - pubmed
The patient underwent uneventful laparoscopic surgery for ovarian cystoma . - pubmed
One hour after completion of surgery , the patient suddenly went into shock , with her blood pressure dropping to 60/40 mmHg . - pubmed
It is important to bear in mind the possibility of postoperative TTP in patients with unexplained hemorrhagic shock after uneventful surgery . - pubmed
Although we expected brain defects , we were astonished to discover that the knockdown zebrafish embryos were actually lacking blood and suffered from defective hemoglobin production . - pubmed
The review describes modern diagnostic criteria for delirium in patients in ICU . - pubmed
OBJECTIVES : To analyze the relationship between gender , age , injury - related variables and rehabilitation outcomes in patients with spinal cord injury ( SCI ) . - pubmed
Patients were described according to age , gender , etiology of SCI , neurological classification , medical complications , American spinal injury association ( ASIA ) classification , length of rehabilitation stay and spinal cord independence measure ( SCIM ) . - pubmed
In 3 patients presenting with massive hematuria after urinary diversion , an iliac artery pseudoaneurysm was found on imaging studies . - pubmed
All patients were successfully treated with a covered stent to exclude the pseudoaneurysm and the arteriovesical fistula . - pubmed
We studied the effectiveness and safety of spironolactone in adults with newly diagnosed systolic heart failure in clinical practice . - pubmed
We identified all adults with newly diagnosed heart failure , left ventricular ejection fraction of & lt;40 % , and no previous spironolactone use from 2006 to 2008 in Kaiser Permanente Northern California . - pubmed
We excluded patients with baseline serum creatinine level of & gt;2.5 mg / dl or a serum potassium level of & gt;5.0 mEq / L. We used Cox regression with time - varying covariates to evaluate the independent association between spironolactone use and death , hospitalization , severe hyperkalemia , and acute kidney injury . - pubmed
Among 2,538 eligible patients with a median follow - up of 2.5 years , 521 patients ( 22 % ) initiated spironolactone , which was not associated with risk of hospitalization ( adjusted hazard ratio 0.91 , 95 % confidence interval 0.77 to 1.08 ) or death ( adjusted hazard ratio 0.93 , confidence interval 0.60 to 1.44 ) . - pubmed
Mycobacterium tuberculosis ( Mtb ) is a causative agent of tuberculosis ( TB ) disease , which has affected approximately 2 billion people worldwide . - pubmed
MATERIALS AND METHODS : Thirty - six patients ( 32 male , and 4 female ; mean age , 29.8 years ) with acute deltoid ligament injury who had undergone MRI participated in this study . - pubmed
OBJECTIVE : To study whether synchronous electrical stimulation of the larynx could be helpful for improving voice quality in patients with dysphonia due to unilateral recurrent laryngeal nerve paralysis ( URLNP ) . - pubmed
Intravenous cobinamide versus hydroxocobalamin for acute treatment of severe cyanide poisoning in a swine ( Sus scrofa ) model . - pubmed
Our objective is to compare the time to return of spontaneous breathing in swine with acute cyanide - induced apnea treated with intravenous hydroxocobalamin , intravenous cobinamide , or saline solution ( control ) . - pubmed
CONCLUSION : Both hydroxocobalamin and cobinamide rescued severely cyanide - poisoned swine from apnea in the absence of assisted ventilation . - pubmed
The purpose of this case report is to remind busy practicing physicians to keep spontaneous renal thromboembolism in differential diagnosis in a patient with acute abdomen . - pubmed
For every 100 patients treated with rtPA , there is a gain of 69.17 QALYs and of $ 408,419 over the lifetime of 100 treated patients with acute ischemic stroke . - pubmed
CONCLUSIONS : This new analysis demonstrates a significant savings associated with the use of rtPA for patients with stroke and provides great support for the increased systematic use of rtPA in the state of South Carolina for patients with acute ischemic stroke . - pubmed
Logistic regression analysis was performed to estimate odds ratios ( ORs ) and their 95 % confidence intervals ( CIs ) for two - time vaccination against measles and rubella viruses as mandatory vaccinations and at least one - time vaccination against mumps and varicella - zoster viruses as optional vaccinations . - pubmed
UNLABELLED : Aim / Materials and Methods : In order to develop better drugs against non - small cell lung cancer ( NSCLC ) , we screened a variety of compounds and treated the human lung adenocarcinoma cell line A549 with different drug concentrations . - pubmed
ACF treatment significantly decreased tumor size and tumor spots on lung surface of tumor - bearing mice . - pubmed
METHODS : Eight Parkinson disease ( PD ) patients with apraxia , 11 patients without apraxia , and 8 healthy volunteers were enrolled . - pubmed
PD patients with apraxia did not have similar facilitation . - pubmed
MAIN FINDINGS : We describe two children with extratemporal pharmacoresistent epilepsy , slowly progressive gray matter volume loss over several years , and evidence of central nervous system inflammation . - pubmed
CONCLUSIONS : These patients illustrate a novel presentation of a subacute inflammatory central nervous system process with epilepsy and progressive cortical volume loss , supporting the role of sequential brain imaging in children with epilepsy . - pubmed
The percentages of patients with spherical equivalents within + -1.00 and + -0.50 diopters of emmetropia were 100 % ( 29 eyes ) and 75.9 % ( 22 eyes ) , respectively , in the iDesign group and 96.7 % ( 29 eyes ) and 70.0 % ( 21 eyes ) , respectively , in the WaveScan group . - pubmed
Patients ' demographics , types of orbito - ocular tumor and their presentation were recorded . - pubmed
Because of that , laboratorial diagnosis of acute undifferentiated febrile illness during epidemic periods is frequently directed towards these viruses , which may eventually hinder the detection of other circulating flaviviruses , including the Saint Louis encephalitis virus ( SLEV ) , which is widely dispersed across the Americas . - pubmed
One of them was a triple co - infection with DENV-1 . - pubmed
This is the first report of SLEV molecular identification in MT . - pubmed
AIMS / HYPOTHESIS : The aim of this study was to determine the incidence and incidence rate trends for type 1 diabetes mellitus in children aged 0 - 14 years , Australia - wide , from 2000 to 2011 . - pubmed
RESULTS : A total of 11,575 cases ( 6,049 boys and 5,526 girls ) of childhood type 1 diabetes mellitus were registered between 2000 and 2011 , giving a mean incidence of 23.6 per 100,000 person - years ( 95 % CI 23.2 , 24.0 ) . - pubmed
To compare patterns of associations of changes in mental and physical health dimensions of health - related quality of life ( HRQoL ) over time with relapse occurrence and changes in Expanded Disability Status Scale ( EDSS ) scores in patients with relapsing multiple sclerosis ( RMS ) . - pubmed
BACKGROUND : The monovalent meningococcal A conjugate vaccine ( PsA - TT , MenAfriVac ) was developed for use in the " meningitis belt " of sub - Saharan Africa . - pubmed
Sensory and autonomic deficits in a new humanized mouse model of familial dysautonomia . - pubmed
Outcomes After Arthroscopic Treatment of Femoroacetabular Impingement for Patients With Borderline Hip Dysplasia . - pubmed
PURPOSE : To compare outcomes after hip arthroscopy for femoroacetabular impingement ( FAI ) in borderline dysplastic ( BD ) patients compared with a control group of nondysplastic patients . - pubmed
High rate of missed HIV infections in individuals with indeterminate or negative HIV western blots based on current HIV testing algorithm in China . - pubmed
It remains unclear if China 's current HIV antibody testing algorithm misses a substantial number of HIV infected individuals . - pubmed
Of 196 specimens with indeterminate or negative results on HIV western blot ( WB ) retrospectively examined by HIV-1 nucleic acid test ( NAT ) , 67.57 % ( 75/111 ) of indeterminate WB samples , and 16.47 % ( 14/85 ) of negative WB samples were identified as NAT positive . - pubmed
The rate of HIV-1 infections missed by China 's current HIV testing algorithm is unacceptably high . - pubmed
In vivo and in vitro evaluation of the effects of Urtica dioica and swimming activity on diabetic factors and pancreatic beta cells . - pubmed
METHODS : Adult WKY male rats were randomly distributed in nine groups : intact control , diabetic control , diabetic + 625 mg / kg , 1.25 g / kg UD , diabetic + 100 mg / kg Metformin , diabetic + swimming , diabetic + swimming 625 mg / kg , 1.25 g / kg UD , and diabetic +100 mg / kg Metformin + swimming . - pubmed
The current data emphasizes the need to individualize DAPT duration at the patient level to balance the clinical benefits of a reduced risk of cardiovascular ischemic events with the greater risk of clinically significant bleeding . - pubmed
Patients at an increased risk of ischemic events and a lower risk of bleeding should be strongly considered for prolonged DAPT beyond the 1 year currently recommended in the practice guidelines . - pubmed
BACKGROUND : Staphylococcus aureus is the major cause of global and nosocomial infections with a significant impact in hospitals worldwide . - pubmed
aureus isolates causing infections in patients admitted to hospitals from Recife city , Brazil , and investigate the prevalence of oxacillin - susceptible mecA - positive S. - pubmed
Subjects were instructed to supplement the study drug with hydrocodone / acetaminophen liquid or acetaminophen for pain as needed . - pubmed
Subjects in the placebo group required statistically significant ( P & lt ; .05 ) higher doses of narcotic and acetaminophen to control pain . - pubmed
Overall , 41 patients died , 47 experienced recurrence . - pubmed
This paper reviews the most recent classification , pathophysiology and imaging findings in clinical research as well as the knowledge gained from studying genetic and lesional animal models of focal cortical dysplasia . - pubmed
This review of this recently gained knowledge will most likely help develop new research models and new therapeutic targets for patients with epilepsy associated with focal cortical dysplasia . - pubmed
Methods Thirty - six obese individuals , median age 44 ( 26 - 64 ) with median body mass index at baseline of 42.5 ( 40.4 - 46 ) were studied before and 15 months after Roux - en - Y gastric bypass . - pubmed
These findings suggest that choice of material is a patient and practitioner preference ; however , for patients at risk of hypoxia - related complications , SiHy materials should be considered . - pubmed
Here , we synthesized this epitope as an octa - branched multiple antigenic peptide ( MAP ) to vaccinate mice implanted with subcutaneous syngeneic colon ( CT26 ) , prostate ( TRAMP - C2 ) or renal ( RENCA ) cell line carcinomas . - pubmed
Mice with regressed tumors demonstrated immune memory , preventing tumor recurrence upon re - implantation ( p & lt ; 0.001 ) . - pubmed
Study of genetic alterations , inherited or acquired , that increase the risk or drive cancers and many other diseases had remained mostly confined to coding sequences of the human genome . - pubmed
MATERIALS AND METHODS : Between January 2004 and January 2011 , 32 inpatients ( 18 male , 14 female ; age , 38 - 61 y ; mean , 48 y ) underwent ACDR for the treatment of ASD after previous ACDF ( single - level : n=12 ; 2 - level : n=15 ; 3 - level : n=5 ) . - pubmed
In 22 patients , ASD occurred above the fusion site , and in 10 it occurred below the site . - pubmed
Before and after ACDR , patients were evaluated using the pain visual analog scale ( VAS ) , the Japanese Orthopedic Association ( JOA ) score , and neck disability index ( NDI ) . - pubmed
At the last follow - up , 2 patients had grade II heterotopic ossification ; 3 patients had aggravated degeneration ( vs. preoperative status ) of the adjacent unfused segment . - pubmed
In a partial thickness burn injury model in piglets , the drug - loaded mats displayed comparable wound closure to commercially available silver - based dressings . - pubmed
OBJECTIVE : Needle - related procedures are the most common sources of pain for children in the hospital setting . - pubmed
Natural Compound Licochalcone B Induced Extrinsic and Intrinsic Apoptosis in Human Skin Melanoma ( A375 ) and Squamous Cell Carcinoma ( A431 ) Cells . - pubmed
These results indicate that Lico B has apoptotic effect on A375 and A431 skin cancer cells , suggesting the potential value of Lico B for the treatment of human melanoma and SCC . - pubmed
Pre- to postoperative coagulation profile of 307 patients undergoing oesophageal resection with epidural blockade over a 10 - year period in a single hospital : implications for the risk of spinal haematoma . - pubmed
Postoperative thrombocytopenia was almost non - existent while aPTT or PT - INR was elevated above the reference range in 129/307 patients : aPTT was elevated in 116/307 while PT - INR was elevated in 32/307 . - pubmed
BACKGROUND : Peripheral neuritis caused by acrylamide is well - known , and many Korean grouting workers are frequently exposed to acrylamide in grouting agents that are injected into cracked concrete . - pubmed
We recently encountered two cases of dermal and neural toxicity in Korean grouting workers with exposure to grouting agents that contained a high concentration of acrylamide . - pubmed
The patient developed peeling skin on both hands while grouting , which progressed to systemic neurological symptoms , such as reduced sensory function and strength . - pubmed
The patient was diagnosed with peripheral neuropathy caused by acrylamide exposure , and fully recovered after conservative treatment and withdrawal of exposure to the grouting agent . - pubmed
CONCLUSIONS : Both workers had workplace acrylamide exposure through dermal contact plus inhalation of dust and vapor , which led to the neural toxicity and dermatitis . - pubmed
Tolerability of a rapid - escalation vinblastine - prednisolone protocol in dogs with mast cell tumours . - pubmed
Dogs with chemotherapy - naive MCTs presenting to the Oncology Service of a single institution were prospectively enrolled to receive escalating vinblastine , and haematology and a standardised quality - of - life questionnaire were assessed prior to each dosage . - pubmed
A total of 70 % of dogs tolerated 3.00 mg / m2 given 7 days apart at day 14 and 21 , although 29 % of dogs developed dose - limiting toxicities and 8 % discontinued the protocol due to toxicity . - pubmed
Glucocorticoid mediates prenatal caffeine exposure - induced endochondral ossification retardation and its molecular mechanism in female fetal rats . - pubmed
Our previous studies discovered that prenatal caffeine exposure ( PCE ) could induce intrauterine growth retardation ( IUGR ) and long - bone dysplasia in offspring rats , accompanied by maternal glucocorticoid over - exposure . - pubmed
This study is to explore whether intrauterine high glucocorticoid level can cause endochondral ossification retardation and clarify its molecular mechanism in PCE fetal rats . - pubmed
The STELLA - LONG TERM study is an ongoing 3 - year post - marketing surveillance study of ipragliflozin in type 2 diabetes ( T2D ) patients . - pubmed
RESEARCH DESIGN AND METHODS : All Japanese patients with T2D who were first prescribed ipragliflozin between 17 July 2014 and 16 October 2015 at participating centers in Japan were registered in STELLA - LONG TERM . - pubmed
CONCLUSIONS : Ipragliflozin was well tolerated and effective in Japanese patients with T2D ; no new safety issues were identified . - pubmed
Ertugliflozin and Sitagliptin Co - initiation in Patients with Type 2 Diabetes : The VERTIS SITA Randomized Study . - pubmed
This study assessed the efficacy and safety of co - initiation of ertugliflozin and sitagliptin compared with placebo in patients with T2DM inadequately controlled on diet and exercise . - pubmed
CONCLUSION : Co - initiation of ertugliflozin with sitagliptin in patients with T2DM inadequately controlled on diet and exercise provided a clinically meaningful improvement in glycemic control over 26 weeks . - pubmed
A rat fracture study was conducted with 4 for 4 weeks to validate its utility in bone fracture healing . - pubmed
Studies suggest an increased frequency of intestinal obstruction in cerebral palsy patients . - pubmed
We present a case of a 21 - year - old man with severe cerebral palsy and kyphoscoliosis . - pubmed
This autopsy highlights the need to maintain a high index of suspicion for small intestinal volvulus in cases of bowel obstruction in cerebral palsy patients to expedite surgery and prevent mortality . - pubmed
Early 7 - day supplemental parenteral nutrition improves body composition and muscle strength in hypophagic cancer patients at nutritional risk . - pubmed
Furthermore , EC showed antidiabetic effects such as improvement in insulin resistance and the down - regulation of the blood glucose level and liver lipid content in type 2 diabetes model mice . - pubmed
Scavenging effect of oxidized biochar against the phytotoxicity of lead ions on hydroponically grown chicory : An anatomical and ultrastructural investigation . - pubmed
To evaluate the scavenging effect of functionalized biochar against the phytotoxicity of Pb2 + , original biochar ( O - B ) was chemically oxidized with either HNO3 or KMnO4 to serve as biofilters ( O - BF , HNO3 - BF and KMnO4 - BF ) to hydroponically grown chicory ( Cichorium intybus L. var . - pubmed
Mycoplasma ovipneumoniae Associated with Polymicrobial Pneumonia in a Free - Ranging Yearling Barren Ground Caribou ( Rangifer tarandus granti ) from Alaska , USA . - pubmed
Mycoplasma ovipneumoniae has been reported in association with respiratory disease in the wild only in members of the subfamily Caprinae of the family Bovidae . - pubmed
ovipneumoniae in a cervid : a free - ranging barren ground caribou ( Rangifer tarandus granti ) yearling with polymicrobial bronchopneumonia . - pubmed
In this study , a novel strain of P. - pubmed
xyllostela ( Fuzhou - R2Ad ) with 120 - fold resistance to Bt Cry2Ad was selected in the laboratory , after screening for 66 generations from the susceptible strain Fuzhou - S. In the absence of Bt Cry2Ad toxin , the Fuzhou - R2Ad had significantly lower fitness as compared to the susceptible strain , which might be related to induced genetic changes to Bt toxins . - pubmed
Copper deficiency can change the microbiome of swine . - pubmed
As multiple inflamed plaques often co - exist in the coronary system , patients are at risk of repeated atherothrombotic cardiovascular events after MI , with rates of 10 - 12 % at one year and 18 - 20 % at three years . - pubmed
A chick - CAM model and mouse model for metastasis confirmed these results in vivo . - pubmed
A randomized crossover trial of elamipretide in adults with primary mitochondrial myopathy . - pubmed
BACKGROUND : This study aims to evaluate the effect of subcutaneous ( SC ) elamipretide dosing on exercise performance using the 6 min walk test ( 6MWT ) , patient - reported outcomes measuring fatigue , functional assessments , and safety to guide the development of the Phase 3 trial . - pubmed
METHODS : MMPOWER-2 was a randomized , double - blind , placebo - controlled , crossover trial that enrolled participants ( N = 30 ) with genetically confirmed primary mitochondrial myopathy . - pubmed
The results of this trial provided an efficacy signal and data to support the initiation of MMPOWER-3 , a 6 - month long , Phase 3 treatment trial in patients with primary mitochondrial myopathy . - pubmed
METHODS : Initial ECG recordings of 41 patients with ApHCM and 72 patients with NSTEACS were analyzed retrospectively . - pubmed
CONCLUSIONS : Compared with NSTEACS patients , ApHCM patients presented higher R and neg T wave voltage as well as a greater ST - segment depression in the 12 - lead ECG . - pubmed
The aim of this study is to evaluate feasibility and the dosimetric improvement of the OA workflow implemented in our institution for locally advanced pancreatic cancer ( LAPC ) patients , in terms of target coverage and organs at risk ( OARs ) sparing . - pubmed
METHODS : A retrospective cohort analysis was performed with 26 patients [ male / female 11/15 ; median age 68 ( range 45 - 83 ) years ] who underwent 3dLPD with stented pancreaticogastrostomy and superior mesenteric or portal vein resection for pancreatic adenocarcinoma between November 2016 and June 2019 . - pubmed
Postoperative complications occurred in 10 ( 38 % ) patients including severe complications ( Clavien - Dindo grade > 2 ) in 4 ( 15 % ) . - pubmed
A polyphasic study was undertaken to establish the position of a Streptomyces strain , isolate PRKS01 - 65 T , recovered from sand dune soil collected at Parangkusumo , Yogyakarta Province , Java , Indonesia . - pubmed
The obese persons have larger foot length , width , higher peak pressure , and contact area . - pubmed
These results indicate that there is considerable asymptomatic infection with SARS - CoV-2 within the healthcare workforce , despite current mitigation policies . - pubmed
Modeling the load of SARS - CoV-2 virus in human expelled particles during coughing and speaking . - pubmed
Watermelon has been used to treat various ailments , such as cardio - vascular diseases , aging related ailments , obesity , diabetes , ulcers , and various types of cancers . - pubmed
BACKGROUND : The purpose of the present study was to assess the radiographic incidence , location , and classification of heterotopic ossification ( HO ) in patients who underwent total ankle arthroplasty ( TAA ) with a 4th generation prostheses at a minimum of 1 - year follow up . - pubmed
Heartbeat : increased use of NOACs in patients with atrial fibrillation reduces health care system costs by reducing stroke incidence . - pubmed
Rituximab as second - line therapy after new direct antiviral agents in peripheral neuropathy Hepatitis C Virus related : always correct therapeutic approach ? - pubmed
Steroid hormone actions in tissue culture cells and cell hybrids -- their relation to human malignancies . - pubmed
Myocardial metabolism of cyclic 3,5 - adenosine monophosphate as influenced by dipyridamole and theophylline in patients with coronary heart disease . - pubmed
The Eastern Cooperative Oncology Group has studied 187 patients with generalized progressive malignant lymphoma classified as having the histologic sub - types histiocytic or mixed . - pubmed
Prostaglandin E and F levels in mouse epidermis are increased by tumor - promoting phorbol esters . - pubmed
We present 2 patients with congenital unialteral multicystic kidney disease with hydropelvis . - pubmed
Proceedings : Circulatory effects of the prostaglandin E1 on spontaneously hypertensive rats and normotensive Wistar rats . - pubmed
Summary -- A patient with follicular carcinoma , Hurthle cell type , who developed subglottic extension and uncontrollable hemoptysis is presented . - pubmed
Laryngectomy and thyroidectomy were eventually required to control hemoptysis ; the patient remains socially functional and asymptomatic after a 30 - month period . - pubmed
The antistaphylococcal sera ( against 11 Oeding strains of S. - pubmed
The number in and distribution of Langerhans ' cells were studied in 11 patients with a maculopapular drug eruption . - pubmed
We used the Structured Interview for DSM - III Personality Disorders to diagnose DSM - III personality disorders systematically in 55 patients with obsessive - compulsive disorder in the active - treatment cell of a controlled trial of clomipramine hydrochloride . - pubmed
Patients with a cluster A personality disorder had significantly higher obsessive - compulsive disorder severity scores at baseline , and the number of personality disorders was strongly related to baseline severity of obsessive - compulsive disorder symptoms . - pubmed
The results of treatment of 72 patients with ampullary choledocholithiasis ( 16 % of the total number of patients with choledocholithiasis ) are presented . - pubmed
The results of clinical and x - ray investigations of 398 patients with disseminated pulmonary lesions were analyzed . - pubmed
When rats are returned to a normoxic environment after chronic exposure to hypoxia , they manifest a striking drinking response . - pubmed
Thrombocytopenia was particularly severe in patients with bone marrow involvement . - pubmed
When female rats were given chlordecone in addition to estrogen plus progesterone , chlordecone reduced the lordosis behavior usually seen in these steroid primed animals . - pubmed
To further examine the role that substance P plays in initiating the observed massive postmortem bronchoconstriction in guinea pig lungs and to explore the role of neural reflex in this airway spasm , six groups of animals were employed : control ( n = 6 ) , morphine ( n = 6 ) , substance P ( n = 5 ) , chronic capsaicin pretreatment + substance P ( n = 5 ) , tetrodotoxin ( TTX ) + acute capsaicin ( n = 4 ) , and chlorisondamine + acute capsaicin ( n = 5 ) . - pubmed
Quantitative radiographic scores for joint space narrowing erosion , and malalignment in the hands and wrists of 200 patients with rheumatoid arthritis ( RA ) were significantly correlated with duration of disease . - pubmed
Immunity patterns during acute infection by Eimeria bovis . - pubmed
The leukotrienes are putative major mediators of human asthma . - pubmed
Nodular granulomatous episclerokeratitis in dogs : 19 cases ( 1973 - 1985 ) . - pubmed
We examined the age and breed prevalence and the response to treatment of 19 dogs with nodular granulomatous episclerokeratitis . - pubmed
In these dogs , this disorder was an idiopathic , bilateral disease characterized histologically by the presence of chronic granulomatous inflammation and reticulin fiber formation . - pubmed
The relationship between tourniquet pressures and neurovascular injury in the human digit is not clearly defined . - pubmed
Reproductive isolation is induced by microorganisms in diverse geographic strains of the flour beetle Tribolium confusum ( Coleoptera : Tenebrionidae ) . - pubmed
Infected strains of T. - pubmed
Ouabain - induced hypertension in a patient with decompensated hypertensive heart disease . - pubmed
Lymphoma susceptibility of the AKR mouse strain acquired before the stage of implantation . - pubmed
[ Radiosensitivity of human malignant melanomas ] . - pubmed
The relationship between hepatocellular carcinoma , cirrhosis and HB virus is briefly discussed in the light of these findings . - pubmed
In some cases of sudden infant death syndrome ( SIDS ) the intestinal flora was found to be dominated by Candida albicans . - pubmed
There is no basis to assume that the activity of yeasts , first of all of Candida albicans , is a contributory factor in the occurrence of SIDS . - pubmed
Cerebrospinal fluid markers in relation to outcome in patients with global cerebral ischemia . - pubmed
To investigate the possibility of improving the accuracy of prognostication in early hypoxic brain damage , 12 patients with global cerebral ischemia ( GCI ) due to circulatory arrest outside hospital were followed until death or for 1 yr . - pubmed
A photogrammetric study of the depth of the central and peripheral anterior chamber of the iris was carried out in 37 subjects with the pigment dispersion syndrome . - pubmed
To test a convenient and reliable neuronal index that suggests the development of autonomous epileptogenicity , we conducted in acute experiments on rabbits a comparative study of the changes in direct cortical responses ( DCRs ) in primary and mirror sites during electrically induced primary ( PRID ) and projected seizure discharges ( PROD ) . - pubmed
Electrograms were recorded from the His bundle area , right ventricular apex , right ventricular inflow tract , and left ventricular apical endocardium in four patients ( aged , 1 , 1 , 1.5 , and 16 years ) with Wolff - Parkinson - White syndrome type B. - pubmed
[ Hoof cyst ( keratoma ) in the horse ] . - pubmed
Long - term diuretic treatment of patients with congestive heart failure is often complicated by hyponatremia and resistance to diuretic treatment , as well as by hypokalemia . - pubmed
Because aldosteronism , such as accompanies the disease and diuretic treatment , increases intracellular sodium , we have measured intracellular sodium and potassium in six patients given a new aldosterone antagonist ( canrenone ) . - pubmed
Neurologic syndromes attributed to conditioning or medications have been reported in BMT recipients . - pubmed
A patient is presented who developed extrapyramidal symptoms on day +56 after allogeneic BMT . - pubmed
Brain magnetic resonance images of this patient demonstrated hyperintense basal ganglia , which has been associated with manganese ( Mn ) toxicity . - pubmed
The patient had received total parenteral nutrition ( TPN ) with standard trace element supplementation and had been cholestatic . - pubmed
Cholestatic patients and those on long - term TPN have been found to have high blood or serum levels of Mn , but generally are asymptomatic . - pubmed
When other cholestatic BMT patients were reviewed , all had elevated serum Mn . - pubmed
Control of pandemic infection of human immunodeficiency virus type 1 ( HIV-1 ) requires some means of developing mucosal immunity against HIV-1 because sexual transmission of the virus occurs mainly through the mucosal tissues . - pubmed
Goose parvovirus is the etiological agent of Derzsy ' s disease , a fatal hepatitis of young geese . - pubmed
The efficacy of short- and long - term treatments with Isoprinosine , an immunomodulatory compound , was studied in Echinococcus granulosus cysts developed in NMRI mice intraperitoneally infected with sheep pulmonary cysts . - pubmed
PARTICIPANTS : A convenience sample of 368 patients presenting to the pediatric ED with respiratory illnesses . - pubmed
CONCLUSION : Clinical evaluation in a pediatric ED does not screen adequately for the detection of hypoxemia and should be supplemented by routine pulse oximetry in all patients with respiratory findings . - pubmed
[ The simultaneous evaluation of preoperative cardiopulmonary functions of esophageal cancer patients in the analysis of expired gas with exercise testing ] . - pubmed
Enrolled were 52 of patients admitted between a period from 1991 to 1993 for thoracic esophageal cancer , who underwent a radical operation of right thoracolaparotomy . - pubmed
In order to evaluate the cytological homology of intermediate cells and melanocytes , and to investigate the function of melanocytes in the inner ear , hearing acuity and cochlear pathology were studied in three strains of mice , namely , wild type mice ( + /+ ) , albino mice without melanin ( c2J / c2J ) , and microphthalmia mice with no melanocytes ( mibw / mibw ) . - pubmed
Our results suggest that : ( a ) acute ethanol intoxication can induce direct contractions ( independent of amine , prostanoid or opioid mediation ) of diverse mammalian cerebral vascular tissues , including those from primates ; ( b ) these contractile responses are heterogeneous along the cerebrovascular tree and independent of endothelial cells ; ( c ) in addition to a need for [ Ca2 +]o , an intracellular release of Ca2 + is needed for ethanol to induce contractions ; and ( d ) hypomagnesemia or Mg deficiency potentiates the contractile effects of ethanol on brain vessels and may be a risk factor for ethanol - related , ischemic stroke events . - pubmed
Form 1 was shared by five rat strains from two vendors ; form 2 was shared by two rat strains from the same vendor ; and forms 3 and 4 were unique to their vendor colonies . - pubmed
These physiologic changes , along with increased pain threshold , mimic the observed effects of morphine and other mu - agonists in the horse . - pubmed
The results of this study suggest that endogenous opioid peptides may modulate pain threshold as well as other physiologic parameters in the horse . - pubmed
Mechanisms involved in the pathogenesis of tubulointerstitial fibrosis in 5/6 - nephrectomized rats . - pubmed
OBJECTIVE : There is a paucity of longitudinal endocrine studies of infertile patients with oligomenorrhoea . - pubmed
PATIENTS : Infertile women with oligomenorrhoea ( PCOS , n = 131 ) presenting to the infertility clinic at the Royal Infirmary , Glasgow . - pubmed
The animals were divided into three groups : control , acidosis , and alkalosis . - pubmed
In patients with cystic fibrosis ( CF ) , respiratory tract infections caused by Staphylococcus aureus and Haemophilus influenzae are followed by Pseudomonas aeruginosa with increasing age . - pubmed
Chronic endobronchial lung infection with P. - pubmed
In Danish CF patients we noted that both onset of initial colonization and chronic lung infection with P. - pubmed
We established a chronic P. aeruginosa lung infection in rats by embedding mucoid bacteria in seaweed alginate and installing the beads intratracheally into the lower part of the left lung . - pubmed
Although the rats did not suffer from CF , the antibody responses and the pathologic changes of the lungs mimicked the findings in CF patients . - pubmed
By using this model in normal and athymic rats we showed that the T - cell response during the " natural " course of the infection played no major role . - pubmed
aeruginosa pneumonia we found that the macroscopic inflammatory response of the lungs was immense and that the natural capacity to clear P. - pubmed
In the chronic rat model we succeeded to improve the survival significantly and to change the inflammatory response subsequent to vaccination from an acute type inflammation dominated by polymorphonuclear leukocytes ( PMNs ) as in CF patients to a chronic type inflammation dominated by mononuclear leukocytes . - pubmed
Furthermore , we found that rats immunized with an alginate containing vaccine had a significantly earlier cellular shift to a chronic type inflammation as well as a significant reduction in the severity of the macroscopic inflammation compared to two other vaccine groups and to nonimmunized controls . - pubmed
OBJECTIVES : To assess the incidence of isolated central nervous system ( CNS ) relapses in patients of acute lymphoblastic leukemia ( ALL ) treated with a protocol containing cranial irradiation and intrathecal methotrexate as CNS directed therapy . - pubmed
Retinal toxicity associated with cisplatin and etoposide in pediatric patients . - pubmed
Retinal toxicity is a side effect of the drug reported in adults , but is not well described in pediatric patients . - pubmed
significantly , both patients had abnormal renal function . - pubmed
We propose that the patients at greatest risk of cisplatin - induced toxicity are those pretreated with nephrotoxic therapy or those with impairment of renal function from other causes . - pubmed
In the case of a critical flail chest with very serious physio - pathological consequences , if the fractures are in technically favourable places , we think it is better to stabilize immediately , since the operating trauma is minimum and in many cases the patient is already intubated and curarized . - pubmed
We report a detailed localization analysis of spontaneous magnetic brain activities in seven BECRS patients using magnetoencephalography ( MEG ) . - pubmed
All patients had BECRS diagnosis with typical seizures and electroencephalographic findings and five patients had minor psychomotor deficits . - pubmed
Increased fast - wave activity was found in all five patients with minor neuropsychological deficits . - pubmed
In patients considered for bidirectional Glenn or Fontan procedures , the association of left superior vena cava ( LSVC ) with ostial atresia of the coronary sinus should be diagnosed preoperatively in order to avoid surgical division or ligation of the LSVC and the negative effect of resulting coronary venous hypertension on myocardial perfusion . - pubmed
Three patients with the interval form of carbon monoxide ( CO ) poisoning were studied for associations between their clinical courses and serial changes on : ( 1 ) MRI ; ( 2 ) EEG ; ( 3 ) single photon emission computed tomography with N - isopropyl - p -[ 123I ] iodoamphetamine ( [ 123I ] IMP SPECT ) ; and ( 4 ) proton magnetic resonance spectroscopy ( [ 1HIMRS ) to evaluate their usefulness as prognostic predictors . - pubmed
These results indicate that [ 1H ] MRS is the most useful indicator in the clinical evaluation of patients with the interval form of CO poisoning . - pubmed
Following animal care committee approval , the effects of continuous infusions of fluvoxamine and sufentanil were studied in behavioural tests ( hot - plate test , tail - flick test , catalepsy test ) in Sprague - Dawley rats with a jugular vein catheter . - pubmed
No animal showed catalepsy . - pubmed
Autoantigen - specific CD4+CD28low T cell subset prevents autoimmune exocrinopathy in murine Sjogren ' s syndrome . - pubmed
Transfer of CD4+CD28low T cells into the animal model actually prevented the development of autoimmune lesions including autoantibody production . - pubmed
These results suggest that a CD4+CD28low T cell subset that is continuously activated by an organ - specific autoantigen may play a regulatory role in the development of organ - specific autoimmune disease in an animal model of SS . - pubmed
Rehabilitation of patients with severe ( Class VI ) maxillary resorption using Le Fort I osteotomy , interposed bone grafts and endosteal implants : 1 - 8 years follow - up on a two - stage procedure . - pubmed
To study possible mechanisms responsible for the increased susceptibility to infection of patients with active systemic lupus erythematosus ( SLE ) , a study of the serum heat - labile opsonic capacity ( HLOC ) in such patients was undertaken . - pubmed
With leukocytes from normal donors , the sera of 12 of 30 patients with active SLE demonstrated decreased HLOC for E. - pubmed
While 8 of 10 patients with active SLE and concomitant infections showed deficient opsonic capacity to E. - pubmed
In the patients surviving infection , recovery of normal serum opsonic capacity was rapid and usually coincided with an increase of serum complement to normal levels . - pubmed
In three patients with active SLE and infection , the causative microorganisms were isolated and opsonic capacity for these organisms tested with the individual patients ' sera . - pubmed
This defect may be an important factor in the increased susceptibility to infections of patients with active systemic lupus erythematosus . - pubmed
A case of a patient with fibrous dysplasia of craniofacial bones associated with primary hyperparathyroidism without additional endocrinophaties or associated disorders , will be presented . - pubmed
In the present study , our results suggest that Caffeine inhibits solid tumour development and pulmonary experimental metastasis induced by B16F10 melanoma cells , in murine model . - pubmed
Odontoclastic resorptive lesion of a mandibular right first molar in a cougar . - pubmed
Helicobacter pylori seropositivity in patients with hyperemesis gravidarum . - pubmed
METHODS : From November 1999 to February 2001 , we enrolled 54 pregnant women with hyperemesis gravidarum and 53 asymptomatic pregnant women in a prospective study . - pubmed
RESULTS : Serologically positive Helicobacter pylori infection was detected in 44 out of 54 patients with hyperemesis gravidarum ( 81.5 % ) whereas 29 out of 53 asymptomatic gravidas ( 54.7 % ) had positive antibody titers for Helicobacter pylori . - pubmed
The ratio of Helicobacter pylori seropositivity in pregnant women with hyperemesis gravidarum was significantly higher than asymptomatic pregnant women ( P<0.01 ) . - pubmed
CONCLUSIONS : There is a significant association between Helicobacter pylori infection and hyperemesis gravidarum in our hyperemetic pregnant patients . - pubmed
[ Assessment of variables relative to prethrombotic state after operation in patients with gynecological malignancies ] . - pubmed
OBJECTIVE : To study the changes in the variables in patients with gynecological malignancies after operation . - pubmed
CONCLUSIONS : Obvious prethrombotic state characterizes the patients with gynecological malignancies after operation . - pubmed
We studied radiographs of 125 children ( 105 boys , 20 girls ) with unilateral Legg - Calve - Perthes ' disease to examine the epiphyseal development of the femoral head in the contralateral ( unaffected ) hip . - pubmed
Mice of the C57BL strain are highly resistant to the oncogenic property of LID-1 polyoma virus , but complete thymectomy within 24 hours of birth rendered these mice susceptible . - pubmed
In thymectomized mice inoculated with adult syngeneic spleen cells , the capacity to resist oncogenesis was restored . - pubmed
The results add further weight to the concept that induction and progression of tumors by polyoma virus has an immunologic basis . - pubmed
We compared two groups of patients : group A--13 patients studied 3 months after operation ; and group B--25 patients studied at a median of 4 years after operation ( range 2 - 8 years ) without coronary occlusive disease ( COD ) . - pubmed
The onset time , rate of rise , and duration of changes in the excitability of corticospinal projections to the agonist muscle were normal in the patients with dystonia . - pubmed
Muscle activity in antagonist and proximal muscles of the upper arm was reduced significantly in the dystonia patients . - pubmed
These findings support the view that movement preparation and initiation at the level of the primary motor cortex is normal in patients with dystonia . - pubmed
Helicobacter pylori causes chronic gastritis worldwide and it is the most important single factor in peptic ulcer disease . - pubmed
pylori infection has also been classified as a class I carcinogen in human gastric cancer . - pubmed
Relation of ECG changes to neurological outcome in patients with aneurysmal subarachnoid hemorrhage . - pubmed
METHODS : All patients admitted to a 31 - bed department of intensive care between 1993 and 2000 with acute aneurysmal SAH documented by cerebral angiography or autopsy were included . - pubmed
RESULTS : Of 159 patients ( 49.6 years [ range : 20 - 75 ] ) with acute SAH , 106 ( 66.7 % ) had abnormal ECGs ( classified by an observer blinded to the patients ' clinical course and outcome . - pubmed
CONCLUSIONS : In patients with acute aneurysmal SAH , repolarization abnormalities are the commonest ECG alterations , and ST depression is more common in patients with poor outcome . - pubmed
Fifteen patients with advanced colorectal cancer refractory to standard chemotherapies consumed capsules compatible with curcumin doses between 0.45 and 3.6 g daily for up to 4 months . - pubmed
The authors report a case of primary cardiac angiosarcoma of the right atrium with pulmonary , hepatic , cerebellar and bony metastases in a 46 - year - old man who clinically presented as pulmonary hemorrhage . - pubmed
Information is limited regarding the histological features related to chronic graft dysfunction and failure in patients with IgA nephropathy developing after renal transplantation . - pubmed
In conclusion , the current study suggests that glomerular crescents are not rare and that they are responsible for chronic graft dysfunction in TxIgAN patients . - pubmed
Streptococcal necrotising fasciitis from diverse strains of Streptococcus pyogenes in tropical northern Australia : case series and comparison with the literature . - pubmed
Therefore , in the present study ITT was performed in healthy adults ( n = 21 ) , adult patients with monaural central perforation ( n = 31 ) or strong scar formations ( n = 24 ) of the tympanic membrane and 18 adult patients after monaural canal wall down surgery . - pubmed
In healthy adults ( 36.50 degrees C vs. 36.51 degrees C ) patients with monaural central perforation of the tympanic membrane ( 36.41 degrees C vs. 36.34 degrees C ) and with monaural strong scar formations in the tympanic membrane ( 36.39 degrees C vs. 36.45 degrees C ) , no significant difference between the right and left ear could be proved . - pubmed
Brain tissue fragments in the amniotic fluid of rats with neural tube defect . - pubmed
We looked for brain tissue fragments in amniotic fluid of rats with NTD as it is the basis for the aspiration hypothesis . - pubmed
Experimental rats received 100,000 U of vitamin A in 1 mL of corn oil on gestational days 8 , 9 and 10 , while control rats received corn oil . - pubmed
A mucosal disease - like condition in lambs with hairy shaker disease . - pubmed
Previously we reported that an ordinarily nonlethal dose of thioacetamide ( 300 mg / kg ) causes liver failure and 90 % mortality in type 1 diabetic rats , primarily because of inhibited tissue repair . - pubmed
On the other hand , the diabetic rats receiving 30 mg thioacetamide / kg exhibited equal initial liver injury and delayed tissue repair compared to nondiabetic rats receiving 300 mg thioacetamide / kg , resulting in a delay in recovery from that liver injury and survival . - pubmed
The aim of this longitudinal investigation was to evaluate the clinical response to scaling and root planing combined with the use of locally delivered minocycline microspheres for 720 days in individuals with advanced chronic periodontitis . - pubmed
UNLABELLED : We investigated the clinical feature of thoracic injury patients , mainly with diaphragmatic injury . - pubmed
From 1993 to 2005 , 739 patients with thoracic injury were treated at our life - saving emergency center . - pubmed
There were more blunt trauma patients than penetrating injury patients ( 693 cases vs 46 cases ) . - pubmed
In addition , thoracoscopy is very useful for both examining and treating traumatic diaphragmatic injury patients . - pubmed
Bovine transcriptome analysis by SAGE technology during an experimental Trypanosoma congolense infection . - pubmed
However , several indigenous West African taurine breeds ( Bos taurus ) present remarkable tolerance to the infection . - pubmed
Human aging is characterized by skeletal muscle wasting , a debilitating condition which sets the susceptibility for diseases that directly affect the quality of life and often limit life span . - pubmed
The identification of the molecular chain able to reverse sarcopenia is a major goal of studies on human aging . - pubmed
RESULTS : In total , 72 proteins were identified and quantified in the comparison of pancreatic juice from pancreatitis patients versus pooled normal control juice . - pubmed
OBJECTIVE : A series of published cases show that repair of brachial plexus injuries by reimplantation of avulsed spinal roots can restore a degree of recovery , particularly to the more proximal shoulder and arm musculature in a proportion of patients . - pubmed
METHODS : This study was based on our previous rat model showing regeneration of severed fibers and resumption of function after transplantation of cultured adult olfactory ensheathing cells into spinal cord injuries and reimplanted dorsal roots . - pubmed
BACKGROUND AND OBJECTIVES : To study the effect of 0.2 mg mL-1 of ondansetron added to morphine patient - controlled analgesia solution after a 4 mg loading dose on the incidence and severity of postoperative nausea and vomiting . - pubmed
Patients who smoked , received antiemetics and hormonal therapy , had a history of motion sickness or gastrointestinal disease , a body mass index & gt;35 or menstruation at the time of the study were excluded . - pubmed
The nausea score , vomiting score and the requested ondansetron dose were evaluated at 1 , 2 , 6 , 12 and 24 h. Patient - satisfaction for nausea / vomiting was recorded at the end of the study . - pubmed
RESULTS : Patient characteristics and cumulative morphine consumption were similar but ondansetron group had higher pain scores ( P = 0.006 ) . - pubmed
The ondansetron group had a lower nausea and vomiting scores , and more patients were free from nausea and vomiting than the control group ( 41 vs. 26 , respectively , P = 0.025 ) . - pubmed
CONCLUSION(S ): Ondansetron 4 mg plus 0.2 mg mL-1 given with PCA morphine can reduce nausea and vomiting thus improving patient satisfaction . - pubmed
We studied the effects of consuming 15 % of the daily caloric intake in the form of pistachio nuts on the lipid profiles of free - living human subjects with primary , moderate hypercholesterolemia ( serum cholesterol greater than 210 mg / dL ) . - pubmed
subjects : 15 subjects with moderate hypercholesterolemia . - pubmed
CONCLUSION : A diet consisting of 15 % of calories as pistachio nuts ( about 2 - 3 ounces per day ) over a four week period can favorably improve some lipid profiles in subjects with moderate hypercholesterolemia and may reduce risk of coronary disease . - pubmed
METHODS : Thirty obese adults ( mean body mass index 29 - 30 kg / m(2 ) ) were randomized to two groups . - pubmed
Subjective visual horizontal in patients with posterior canal benign paroxysmal positional vertigo . - pubmed
CONCLUSION : Patients with posterior canal benign paroxysmal positional vertigo ( p - BPPV ) could have mild excitation in the vestibular system on the affected side . - pubmed
While subjective visual horizontal ( SVH ) mainly reflects utricular function , there is less documentation on SVH in patients with p - BPPV . - pubmed
PATIENTS AND METHODS : Twenty - eight patients with unilateral idiopathic p - BPPV were enrolled . - pubmed
For comparison , 17 patients with vestibular neuritis and 45 patients with cerebello - pontine angle ( CPA ) tumor were also examined . - pubmed
Conversely , deviation of SVH was toward the affected side down in 88.2 % of patients with vestibular neuritis and in 75.6 % of patients with CPA tumor . - pubmed
PATIENTS AND METHODS : A questionnaire identified pain level in a cohort of patients that had previously undergone corrective groin hernia surgery . - pubmed
RESULTS : Thirty - two patients were evaluated for response rate ( RR ) and skin toxicity to establish the best management . - pubmed
Of 34 patients evaluable for cutaneous toxicity , 10 patients ( 29 % ) presented with grade 1 eruption , 13 ( 38 % ) with grade 2 eruption , and 4 ( 12 % ) with grade 3 eruption . - pubmed
Allergic reactions such as flushing and urticaria ( grade 2 ) were seen in 2 patients ( 6 % ) . - pubmed
The patient was a 36 - year - old man with polyarthralgia , fatigue and swelling of his upper eyelids and all four limbs . - pubmed
We present our experience with computed tomographic angiography in 3 pediatric patients with vascular injuries secondary to blunt trauma . - pubmed
SUMMARY : Among gram - positive bacterial infections , differentiating between healthcare - associated and community - associated methicillin - resistant Staphylococcus aureus infections is becoming more difficult and can seriously impact therapeutic strategies and hence outcomes . - pubmed
Early bronchodilatory effects of budesonide / formoterol pMDI compared with fluticasone / salmeterol DPI and albuterol pMDI : 2 randomized controlled trials in adults with persistent asthma previously treated with inhaled corticosteroids . - pubmed
Two identically designed , randomized , multicenter , single - dose , crossover studies were conducted in patients aged & gt ; or = 18 years with mild to moderate asthma previously treated with inhaled corticosteroids . - pubmed
This study reviews 40 patients with primary isolated arthritis of the medial compartment of the knee that underwent unicompartmental knee arthroplasty through a minimally invasive approach . - pubmed
Preclinical studies showed the ability of the drugs to reverse hyperglycaemia in diabetic non - obese diabetic ( NOD ) mice providing rationale for clinical trials with the agents . - pubmed
The former two drugs have been tested in subjects with new onset type 1 diabetes . - pubmed
The assessment of cerebral autoregulation is a key to the optimisation of cerebral perfusion pressure in patients with brain injury . - pubmed
Rare cases of inflammatory pseudotumor ( IPT ) in two adolescents are reported . - pubmed
These two cases are reported to emphasize IPT of the liver as a differential diagnosis of hepatic masses in children because recognition of this condition before operation can avoid unnecessary surgery . - pubmed
In honeybee ( Apis mellifera ) societies , the queen controls the development and the caste status of the members of the hive . - pubmed
We describe the cases of two men , one of whom was a non - alcoholic 50 - year - old man who had been on hunger strike for 50 days and who was admitted to hospital with dysarthria , unstable gait , disorientation , ophthalmoplegia and ataxia . - pubmed
In both patients , magnetic resonance imaging showed bilateral and symmetrical injuries around Silvio 's aqueduct and in the periventricular region of both thalami . - pubmed
Patients with phlebolymphedema have skin changes of venous insufficiency , which are easy to recognize . - pubmed
VARIATIONS IN CO ( 2 ) REQUIREMENTS AMONG BOVINE STRAINS OF BACILLUS ABORTUS . - pubmed
Strains of Bacillus abortus freshly isolated vary in their CO ( 2 ) requirements . - pubmed
A young woman with renal colic presenting with urogenital anomaly : a case report . - pubmed
CONCLUSION : Understanding the predictors of early treatment discontinuation in the care of schizophrenia patients is important for the development of interventions to improve treatment outcome . - pubmed
Anesthesia with the ProSeal Laryngeal Mask Airway for a patient with Mounier - Kuhn syndrome . - pubmed
BACKGROUND : Patients with osteoarthritis of the hip demonstrate a limp while ambulating , and persistent asymmetric limb loading following unilateral total hip arthroplasty might induce further complications in the affected and contralateral limbs . - pubmed
During the past 50 years , a variety of bone - seeking radiopharmaceuticals have been developed and evaluated to detect skeletal metastases by imaging ( 1 - 3 ) or as pain palliative agents in patients ( 4 ) . - pubmed
Two novel Gram - reaction - positive , rod - shaped actinobacterial strains , designated RP - B26(T ) and RP - B30(T ) , were isolated from rhizosphere soil of a cliff - associated plant ( Peucedanum japonicum Thunb . ) - pubmed
The DNA G+C contents of strains RP - B26(T ) and RP - B30(T ) were 73.0 and 71.7 mol% , respectively . - pubmed
Levels of DNA - DNA relatedness between the isolates were 44.9 + - 1.5 % ( thermal renaturation method ) and 43.2 % ( photobiotin - labelled method ) ; the isolates showed low DNA - DNA relatedness values ( & lt;11 % ) to the most closely related strain , N. - pubmed
( type strain RP - B26(T ) = KCTC 19368(T ) = DSM 19768(T ) ) and Nocardioides maradonensis sp . - pubmed
( type strain RP - B30(T ) = KCTC 19384(T ) = DSM 19769(T ) ) are proposed . - pubmed
BACKGROUND : A perforating phenotype is associated with an increased postoperative morbidity in patients with Crohn ' s disease undergoing ileocolic resection . - pubmed
METHODS : In all , 197 patients underwent 231 bowel resections for perforating ileitis between 1992 and 2009 . - pubmed
Patients with symptoms lasting & gt;5 months prior to surgery had a higher incidence of postoperative septic complications ( 31 % versus 13 % , P = 0.002 ) , both by univariate and multivariate analysis . - pubmed
CONCLUSIONS : Delay of surgery in patients presenting with symptoms attributable to perforating ileitis is associated with an increased postoperative risk . - pubmed
Impact of positive surgical margins on prostate - specific antigen failure after radical prostatectomy in adjuvant treatment - naive patients . - pubmed
Despite excellent surgical cancer control , up to 40 % of patients will have biochemical recurrence following radical prostatectomy ( RP ) for localized prostate cancer . - pubmed
However , decision of further management ( adjuvant or salvage therapy ) in patients with PSM remains controversial , and many debatable questions arise concerning the incidence of clinical progression and the impact of systematic adjuvant treatment on the cancer specific and overall survival . - pubmed
METHODS : A total of seven patients with nine adrenal metastases treated with SBRT at the University of Pittsburgh Cancer Institute were retrospectively studied . - pubmed
Follow - up imaging for six patients , and eight metastatic lesions , revealed one complete response , two partial responses and five stable lesions . - pubmed
[ Diagnostic approach to Streptococcus bovis bacteremia , or the limits of the evidence - based medicine ] . - pubmed
Genetically inbred Balb / c mice differ from outbred Swiss Webster mice on discrete measures of sociability : relevance to a genetic mouse model of autism spectrum disorders . - pubmed
Moreover , because impaired sociability may influence the social behavior of stimulus mice , we also measured the proportion of total episodes of social approach made by the stimulus mouse while test and stimulus mice were allowed to interact freely . - pubmed
The data support previous reports that the Balb / c mouse is a genetic mouse model of impaired sociability . - pubmed
The data also show that the behavior of the social stimulus mouse is influenced by the impaired sociability of the Balb / c strain . - pubmed
Interestingly , operationally defined measures of sociability did not necessarily correlate with each other within mouse strain and the profile of correlated measures differed between strains . - pubmed
rearing , grooming and wall climbing ) recorded during the session of free interaction between the test and social stimulus mice were more intensely displayed by Swiss Webster than Balb / c mice , suggesting that the domains of sociability and " restricted repetitive and stereotyped patterns of behavior " are independent of each other in the Balb / c strain . - pubmed
AIMS : Peak oxygen uptake ( VO(2 ) ) is diminished in patients with heart failure with preserved ejection fraction ( HFpEF ) suggesting impaired cardiac reserve . - pubmed
To test this hypothesis , we assessed the haemodynamic response to exercise in HFpEF patients . - pubmed
METHODS AND RESULTS : Eleven HFpEF patients ( 73 + - 7 years , 7 females/4 males ) and 13 healthy controls ( 70 + - 4 years , 6 females/7 males ) were studied during submaximal and maximal exercise . - pubmed
The DeltaQ(c)/DeltaVO(2 ) slope was abnormally elevated in HFpEF patients vs. controls ( 11.2 + -3.6 vs. 8.3 + - 1.5 ; P = 0.015 ) . - pubmed
CONCLUSION : Contrary to our hypothesis , cardiac reserve is not significantly impaired in well - compensated outpatients with HFpEF . - pubmed
Future treatment of patients with HCV cirrhosis . - pubmed
Of all hepatitis C virus ( HCV ) patients , those with cirrhosis are most in need of treatment because of increased morbidity and mortality . - pubmed
However , the sustained virological response ( SVR ) is lower in patients with cirrhosis . - pubmed
In naive patients , the SVR rate with the triple regimen with boceprevir was increased by 14 % in patients with severe fibrosis or cirrhosis compared with PR . - pubmed
PSI risk - adjusted rate increased linearly by severity of patient indication : claudicants ( OR = 0.40 ; 95 % CI , 0.35 - 0.46 ) , rest pain patients ( OR = 0.78 ; 95 % CI , 0.69 - 0.90 ) , ulcer ( OR = 1.20 ; 95 % CI , 1.07 - 1.34 ) , and gangrene patients ( OR = 1.85 ; 95 % CI , 1.66 - 2.06 ) . - pubmed
CONCLUSIONS : Patient safety events in vascular surgery were high and varied by procedure , with amputations and open abdominal aortic aneurysm repair having considerably more potential adverse events . - pubmed
The Azacitidine is actually authorised for the treatment of CMML patients with 10 - 29 % marrow blasts without myeloproliferative disorder , who are not eligible for haematopoietic stem cell transplantation . - pubmed
Here we report a case of an atypical delayed and prolonged hematologic toxicity during Azacitidine treatment in a CMML patient ; furthermore we also reviewed the literature regarding the efficacy of the drug and the management of hematologic adverse effects , in term of dose adjustments or alternative schedule of administration , in specific CMML setting . - pubmed
A total of 157 children ages 10 to 18 and their parents enrolled in a pediatric pain rehabilitation program completed the Pain Stages of Change Questionnaire ( PSOCQ youth and parent versions ) at pretreatment , posttreatment , and short - term follow - up . - pubmed
Collagen sponge scaffolds containing 2,000 - 30,000 hVSEL cells were implanted into cranial defects generated in SCID mice . - pubmed
Most of the studies included patients with prostate cancer . - pubmed
METHODS : Women with measurable recurrent or persistent endometrial cancer and documented disease progression were treated with ridaforolimus 12.5 mg intravenously once daily for 5 consecutive days every 2 weeks in a 4 - week cycle . - pubmed
CONCLUSION : Single - agent ridaforolimus has antitumor activity and acceptable tolerability in advanced endometrial cancer patients . - pubmed
BACKGROUND : Osteoarthritis ( OA ) is a frustrating disease for both patient and physician because neither cause nor cure is known and there are currently no disease - modifying drugs . - pubmed
METHODS : After reviewing disease progression in human OA , as demonstrated by histological analyses , the reasons for cartilage erosion are explored and possible therapeutic approaches are highlighted . - pubmed
Odds of starting a race and of earning money racing were lower for horses with any lesion and lower for horses with proximal phalangeal dorsoproximal articular margin chip fracture , proximal sesamoid bone fracture or sesamoiditis , or wedge - shaped central or third tarsal bones , compared with horses that had no lesion . - pubmed
For horses that raced , proximal phalangeal dorsoproximal articular margin chip fractures were associated with lower lifetime earnings , and flattening of the medial femoral condyle was associated with fewer 3 - year - old racing starts , compared with values for horses that had no lesion . - pubmed
In CNE2 and HONE1 nude mice xenograft models , orally NVP - BEZ235 efficiently attenuated tumor growth with no obvious toxicity . - pubmed
Based on the above results , NVP - BEZ235 , which has entered phase I / II clinical trials in patients with advanced solid tumors , has a potential as a monotherapy or in combination with CDDP for NPC treatment . - pubmed
The protective effects of volatile anesthestics against the bronchoconstriction induced by an allergic reaction in sensitized rabbit pups . - pubmed
Inhalation of volatile anesthetics , particularly sevoflurane , promotes an earlier easing of the bronchospasm ; this beneficial profile may be advantageous in children with atopic lung diseases . - pubmed
In human sepsis , there is new interest in glucocorticoid therapy at a physiological dose after reports of improved response to vasopressor drugs and decreased mortality in a selected group of patients . - pubmed
Nine patients with septic shock and nine healthy controls were prospectively enrolled . - pubmed
Mononuclear cells and serum samples were obtained from the patients with sepsis on admission to the Intensive Care Unit and on the day of discharge from hospital , and from healthy volunteers matched by age and sex with the patients . - pubmed
Glucocorticoid sensitivity was studied in control mononuclear cells cultured in the presence of serum from normal or septic patients . - pubmed
In addition , it performed much better in acute toxicity tests and via oral administration in mice than cyclosporin A ( CsA ) , with few adverse reactions and low toxicity in experimental animals . - pubmed
Oral administration of isogarcinol in mice resulted in a dose - dependent decrease in delayed type hypersensitivity ( DTH ) and prolonged graft survival in allogeneic skin transplantation . - pubmed
METHODS : In this clinical trial , 56 cases of acne patients with yin - deficiency - inner heat type were enrolled . - pubmed
The therapeutic effect was evaluated by skin lesion score and patients ' constitution score . - pubmed
RESULTS : Of the patients in the moxibustion and control groups , 2 and 1 was cured ( the acne subsided above 90 % and symptoms disappeared ) , 14 and 6 experienced marked improvement ( the acne subsided by 60%-90 % and symptoms were obviously relieved ) , 10 and 15 were effective ( the acne subsided by 30%-59 % and symptoms were relieved ) , 3 and 5 invalid ( the acne subsided by below 30 % and symptoms were worsen ) , respectively . - pubmed
CONCLUSION : Suspended moxibustion is effective in improving both skin lesion and yin - deficiency constitution in acne patients with yin - deficiency - inner heat type . - pubmed
Our objective was to examine the effect of nanoparticulate paclitaxel on prostate cancer cells derived from castration - resistant prostate cancer in men and dogs , as companion dogs represent a unique naturally occurring model of castration - resistant prostate cancer . - pubmed
RESULTS : Nanoparticulate paclitaxel was as effective as standard paclitaxel in decreasing cell viability , decreasing colony forming ability , and inducing apoptosis in human and canine prostate cancer cells in a dose - dependent manner . - pubmed
CONCLUSIONS : Nanoparticulate paclitaxel is as effective as paclitaxel in decreasing cell viability , initiating apoptosis , decreasing cell survival , and causing rigidity of microtubules in both human and canine castration - resistant prostate cancer . - pubmed
Therefore , this study was conducted to evaluate the medium - term effects of LAGB on weight loss and metabolic outcomes of obese patients with different body mass index ( BMI ) in China . - pubmed
The patients were evaluated at years 1 , 3 , and 5 after operation in the outpatient clinic , and the weight loss , metabolic parameters , and remission of comorbidities were measured . - pubmed
CONCLUSIONS : Relatively low medium - term weight loss , metabolic improvement , and resolution or remission of obesity - related comorbidities and high reoperation rate were observed in our population of patients with BMI & gt;= 35 kg / m2 who underwent LAGB . - pubmed
Serotonin and sudden death : differential effects of serotonergic drugs on seizure - induced respiratory arrest in DBA/1 mice . - pubmed
In the DBA/1 mouse model of sudden unexpected death in epilepsy ( SUDEP ) , administration of a selective serotonin ( 5 - HT ) reuptake inhibitor ( SSRI ) , fluvoxamine , completely suppressed seizure - induced respiratory arrest ( S - IRA ) at 30 min after administration ( i.p . ) - pubmed
Serotonergic antagonists may be problematic in patients with epilepsy . - pubmed
Cytotoxicity of TiO2 nanoparticles to mussel hemocytes and gill cells in vitro : Influence of synthesis method , crystalline structure , size and additive . - pubmed
A 57 - year - old man presented to the authors ' department with pain over the right hip joint over a 3 - month period . - pubmed
Microbiologic examination showed a Staphylococcus aureus strain . - pubmed
The aim of this study was to determine if SUA levels are associated with nutritional risk and consequently with adverse clinical outcomes in MHD patients . - pubmed
The effect of re - operation on survival in patients with recurrent glioblastoma . - pubmed
PATIENTS AND METHODS : A retrospective analysis was performed for GBM patients followed between 01/2005 and 06/2010 at our Institution . - pubmed
RESULTS : Two hundred and thirty - two patients with recurrent GBM were evaluated . - pubmed
CONCLUSION : Second surgery might have a limited impact in the clinical course of recurrent GBM patients . - pubmed
Although otitis media is extremely frequent in children , tympanogenic labyrinthitis is not commonly observed , which suggests the existence of a potent anti - inflammatory mechanism modulating cochlear inflammation . - pubmed
This surgical approach enables rapid and direct delivery into the scala tympani while minimizing blood loss and avoiding animal mortality . - pubmed
Lymph node and spleen cells of mice doubly immunized by epicutaneous and intravenous hapten application produce a suppressive component that inhibits the action of the effector T cells that mediate contact sensitivity reactions . - pubmed
Quantitative PCR analyses of DNA from liver tissue , ocular , oral , nasal , and cloacal swabs were all positive for ranavirus , and sequencing of the template confirmed infection with a FV3 - like ranavirus . - pubmed
This is the first report of morbidity and mortality of a mud turtle with a systemic ranaviral infection . - pubmed
Staphylococcus aureus is a leading cause of skin and soft tissue infections , foreign body infections , and infective endocarditis . - pubmed
In case of endovascular infection with S. - pubmed
Infections caused by Staphylococcus aureus strains with Methicillin resistance are associated with increased mortality and morbidity , aggressive course , multiple drug resistance and hospital outbreaks . - pubmed
We report a case of multiple hereditary exostosis in a 33 - year old patient with clinical symptoms of pain and impression of a growing mass of the left shoulder alerting potential risk of malignant transformation of an osteochondroma . - pubmed
A low serum Mg level on admission ( HMg0 ) has been associated with more severe presentation in patients with subarachnoid hemorrhage . - pubmed
We sought to determine the incidence and clinical significance of HMg0 in patients with ICH . - pubmed
METHODS : We reviewed the records of consecutive patients with ICH over a 2 - year period . - pubmed
CONCLUSIONS : HMg0 occurs in one third of patients with ICH and is associated with more severe presentation and intraventricular hemorrhage . - pubmed
We recorded blood pressure ( BP ) and bilateral middle cerebral artery flow velocity ( MCAv ) in a cohort of TIA patients ( n = 17 ) , and age - matched controls ( n = 15 ) . - pubmed
BPV attenuation may be an important therapeutic strategy for enhancing secondary stroke prevention in patients who suffer a TIA . - pubmed
Cognitive training has been shown to result in improved behavioral performance in normal aging and mild cognitive impairment ( MCI ) , yet little is known about the neural correlates of cognitive plasticity , or about individual differences in responsiveness to cognitive training . - pubmed
In this study , 21 healthy older adults and 14 patients with MCI received five weeks of adaptive computerized working - memory ( WM ) training . - pubmed
Although MCI patients showed improved behavioral performance at low WM load after training , no evidence was found for training - related changes in prefrontal activation . - pubmed
To compare physiological and photochemical competency , the pigment composition of discrete life cycle stages was determined for the common resting cyst - producing dinoflagellate Scrippsiella lachrymosa . - pubmed
Original Research : Diametric effects of hypoxia on pathophysiology of sickle cell disease in a murine model . - pubmed
We report that hypoxia rapidly decreased oxygen saturation in transgenic sickle cell disease mice , but this effect was immediately buffered by a robust ventilatory response . - pubmed
Synergistic and attenuated effect of HSS in combination treatment with docetaxel plus cisplatin in human non - small - cell lung SPC - A-1 tumor xenograft . - pubmed
Many reports indicated that patients with tumors can benefit from adjuvant chemotherapy drugs . - pubmed
PATIENTS AND METHODS : A 49 - year - old man presented a rash on the seventh day of treatment with esomeprazole , clarithromycin and amoxicillin prescribed for gastritis involving Helicobacter pylori . - pubmed
Cardiac glycosides from the seeds of Thevetia peruviana and their pro - apoptotic activity toward cancer cells . - pubmed
Cytotoxicity of them toward cancer cell lines P15 ( human lung cancer cell ) , MGC-803 ( human gastric cancer cells ) , SW1990 ( human pancreatic cancer cells ) , and normal hepatocyte cell LO2 suggested that compound 1 could selectively inhibit the proliferation of cancer cell lines with IC50 from 0.05 to 0.15 muM. - pubmed
METHODS : The magnetic resonance imaging features of 20 patients of anaplastic meningioma were compared with those of 30 patients of atypical meningioma retrospectively , all of which were confirmed by surgery and pathology . - pubmed
There were no postoperative symptoms of urinary incontinence , and the patient was completely satisfied . - pubmed
Effects of diet composition on weight loss , metabolic factors and biomarkers in a 1 - year weight loss intervention in obese women examined by baseline insulin resistance status . - pubmed
OBJECTIVE : To examine the effect of diet composition on weight loss and metabolic , hormonal and inflammatory factors in overweight / obese women stratified by insulin resistance status in a 1 - year weight loss intervention . - pubmed
METHODS AND RESULTS : Nondiabetic women who were overweight / obese ( n=245 ) were randomly assigned to a lower fat ( 20 % energy ) , higher carbohydrate ( 65 % energy ) diet ; a lower carbohydrate ( 45 % energy ) , higher fat ( 35 % energy ) diet ; or a walnut - rich ( 18 % energy ) , higher fat ( 35 % energy ) , lower carbohydrate ( 45 % energy ) diet . - pubmed
Prescribing walnuts is associated with weight loss comparable to a standard lower fat diet in a behavioral weight loss intervention . - pubmed
Disease progression was easily monitored by repeated quantification of Gaussia princeps luciferase activity in peripheral blood . - pubmed
MATERIALS AND METHODS : A prospective randomized open labeled clinical trial included 180 women with missed miscarriage in gestational age between 13 and 24 wks . - pubmed
Tubular epithelial cell - specific targeted deletion of Grem1 ( TEC - grem1 - cKO ) mice displayed a milder response in the acute injury and recovery phases of the folic acid model . - pubmed
Overweight dogs exercise less frequently and for shorter periods : results of a large online survey of dog owners from the UK . - pubmed
Canine obesity is now the number one health concern in dogs worldwide . - pubmed
Information gathered included signalment , overweight status , and owner - reported information on duration and frequency of dog walking . - pubmed
Data were available from 11 154 adult dogs , and 1801 ( 16 1 % ) of these were reported as overweight by their owners . - pubmed
Vicarious Social Defeat Stress Induces Depression - Related Outcomes in Female Mice . - pubmed
Thus , the objective of the current investigation was to examine whether exposure to emotional and/or psychological stress ( ES ) mediates depression - related outcomes in female mice . - pubmed
RESULTS : When compared with control mice , female mice exposed to ES displayed decreased social behavior and preference for sucrose , along with increased immobility in the tail suspension test . - pubmed
CONCLUSIONS : Our data indicate that female mice exposed to ES display a behavioral and physiologic profile that mimics symptoms of depression in the clinical population . - pubmed
Paroxysmal Tonic Upgaze in Children : Three Case Reports and a Review of the Literature . - pubmed
In general , the entity was defined as an apparently benign phenomenon with normal investigations and eventual complete resolution of the symptoms , although some authors reported on patients with associated neurologic signs , such as ataxia , developmental delay , and abnormal brain magnetic resonance imaging finding . - pubmed
Paroxysmal tonic upgaze attacks have decreased in number or disappeared in 2 patients , but 1 patient exhibited mild abnormalities on magnetic resonance imaging and had relatives with epilepsy . - pubmed
It is important to recognize the clinical presentation of paroxysmal tonic upgaze and distinguish the disorders from epilepsy for deciding the treatment and prognosis of the patients . - pubmed
A novel experimental model for human mixed acinar - ductal pancreatic cancer . - pubmed
In large part , this results from the lack of an animal model that mimics pancreatic cancer in man . - pubmed
We describe a novel experimental model of pancreatic cancer that shares the genetic background , histologic features and natural history of human mixed acinar - ductal carcinoma . - pubmed
This novel approach represents the first pancreatic cancer model that does not involve alterations of embryonic development , which is inherent with transgenic mice or knockout mice models . - pubmed
This novel experimental human pancreatic cancer model can be used to more effectively test new anti - cancer drug to inhibit tumor progression in situ and to retard metastases . - pubmed
Furthermore , our method of injecting lentivirus containing oncogenes and molecules implicated in the development of pancreatic can be employed in diabetic and obese mice , two common metabolic conditions characterized by an increased incidence of pancreatic cancer . - pubmed
MATERIALS AND METHODS : The data included in this study were obtained from 352 renal transplant patients who were consulted by the pulmonology department regarding hemoptysis between 2011 and 2017 at Baskent University . - pubmed
Hemoptysis was detected in 17 patients ( 4.8%),with 3 ( 0.85 % ) having massive hemoptysis as a result of diffuse alveolar hemorrhage syndrome . - pubmed
Fourteen of our patient group ( 4 % ) had pneumonia , and Aspergillus species was detected in 5 patients ( 1.4 % ) . - pubmed
CONCLUSIONS : Hemoptysis is an important respiratory symptom in renal transplant patients . - pubmed
We studied 37 men with primary IO diagnosed by liver histology . - pubmed
Herein , we describe a patient with red tattoo pigment - induced granulomatous dermatitis that histologically revealed a very rare granuloma annulare - like reaction . - pubmed
Clinical presentation A 20 - year - old male with a history of tuberous sclerosis , X - linked intellectual disability , and epilepsy presented to the emergency department with two days of nausea , emesis , seizures , and two months of progressive proptosis . - pubmed
Objective : To observe the clinical effects of Huanshao Capsules ( HSC ) combined with levocarnitine ( LC ) on asthenospermia , oligospermia , teratozoospermia , and the semen parameters of the patients . - pubmed
METHODS : This randomized controlled clinical study included 186 infertility patients with spleen and kidney asthenia . - pubmed
Moreover , diabetic nephropathy ( DN ) rats model was induced by intraperitoneal injection of a small dose of streptozotocin ( 45 mg / kg ) and high - fat diet and plus 5 % glucose drinking water . - pubmed
Relation between cutaneous and extracutaneous complications in pediatric patients with type 1 diabetes . - pubmed
Background : The relationship between cutaneous and extracutaneous complications in pediatric patients with type 1 diabetes is unclear . - pubmed
Objective : The objective of the current study is to investigate the relationship between skin disorders and diabetic microangiopathic changes in pediatric and adolescent patients with type 1 diabetes . - pubmed
Patients and methods : Eighty patients with type 1 diabetes and 50 healthy controls were enrolled in the study . - pubmed
The significant association between diabetic nephropathy and cutaneous lesions support the concept that cutaneous lesion in diabetes is a reflection of diabetic angiopathy , highlighting the importance of identifying patients at risk of other microvascular complications . - pubmed
Randomized clinical trial to evaluate the efficacy of prostaglandin F2alpha to treat purulent vaginal discharge in lactating dairy cows . - pubmed
The objectives of this study were ( 1 ) to assess the effect of purulent vaginal discharge ( PVD ) on reproductive performance using a 4 - point vaginal discharge score ( VDS ) and ( 2 ) to evaluate the effect of PGF2alpha treatment in cows with PVD on reproductive performance . - pubmed
Holstein cows ( n = 2,473 ) from 1 commercial dairy farm had their vaginal discharge scored at 32 + - 3 d in milk ( DIM ) using a 4 - point scale . - pubmed
The effect of VDS and the effect of PGF2alpha in cows with PVD on reproductive performance were evaluated separately . - pubmed
Although multiparous cows with PVD treated with PGF2alpha had increased odds of pregnancy at first AI , no treatment effect was observed on the hazard of conceiving within 200 DIM . - pubmed
Our results do not support the blanket use of PGF2alpha as a treatment option in postpartum dairy cows having PVD . - pubmed
To my knowledge , this is the first report of downy mildew caused by P. - pubmed
Our primary objective was to evaluate the impact of early AKI episodes that are persistent or progressive in nature , on patient outcomes and graft survival . - pubmed
We evaluated the incidence density rate ( IDR ) of graft failure and the time to graft failure in patients with persistent or progressive AKI ( ppAKI ) as compared to controls . - pubmed
Toxoplasma gondii is an obligate intracellular parasite responsible for toxoplasmosis , which can cause severe disease in the fetus and immunocompromised individuals . - pubmed
Additionally , the survival time of mice immunized with rTgMIF was longer than that of the mice in control groups after challenge infection with virulent T. - pubmed
Moreover , the number of brain tissue cysts in vaccinated mice was reduced by 62.26 % compared with the control group . - pubmed
Our objective was to determine the frequency of different clinical outcomes in patients presenting with TM . - pubmed
In total 131 patients of TM were enrolled and treated as per standard protocol , and re - evaluated after eight weeks for assessment of clinical outcomes . - pubmed
Out of 131 cases , 36.6 % of patients had full recovery and 63.4 % had poor recovery while recurrence occurred in 66.7 % cases . - pubmed
In conclusion , although aniseikonia was gradually relieved after RD surgery during a 1 - year follow - up period , approximately half of patients had aniseikonia and almost all of them had micropsia . - pubmed
The objective of this study was to compare thyroid function between suicide attempters and non - suicide attempters in a large sample of first episode drug naive ( FEDN ) MDD patients , which received little systemic investigation . - pubmed
METHODS : A total of 1718 outpatients with diagnosis of MDD at their first episode were recruited . - pubmed
In our retrospective statistical study we evaluated the autoantibody test results of serum and CSF from 2362 patients with suspected PNS and 1034 patients with suspected AE . - pubmed
The number of patients with suspected PNS and AE shows an increasing tendency , where the autoantibody testing with modern laboratory diagnostic methods helps in the early introduction of the appropriate therapy . - pubmed
As an important derivative of the herb medicine Artemisia annua L. , dihydroartemisinin ( DHA ) exhibits anti - hepatocellular carcinoma ( HCC ) activities . - pubmed
One patient had bilateral trochanteric ulcers . - pubmed
Six major challenges were identified for CAMH policy in LMICs : ( i ) poor public awareness and low political willingness ; ( ii ) stigma against mental disorders ; ( iii ) biased culture values toward children , adolescents and CAMH , from developmental nihilism to medicalization ; ( iv ) the lack of CAMH data and evidence , from service statistics to program evaluation ; ( v ) the shortage of CAMH resources , including human resources , service facilities , and funding ; and ( vi ) unintended consequence of international support , including reducing local responsibilities , planning fragmentation , and unsustainability . - pubmed
In this study , we combine MRI acquired from a large typically - developing childhood population ( n=768 ) with comprehensive human gene expression databases to test the hypothesis that disrupted mechanisms common to neurodevelopmental disorders are encoded by genes expressed early in development and nested within those associated with typical cortical remodelling in childhood . - pubmed
OBJECTIVE : The aim of this study was to compare the incidence of hypotension with norepinephrine infusion or leg wrapping with a control group in women undergoing caesarean delivery with spinal anaesthesia . - pubmed
In group Norepinephrine , the women received a norepinephrine infusion according to their body weight , while group Leg Wrapping and the control group received a 0.9 % normal saline infusion at a similar rate . - pubmed
BACKGROUND : This study determined whether the relationship between predicted propofol effect site concentration ( Ce ) and observer 's assessment of alertness / sedation scale ( OAA / S ) or Bispectral Index ( BIS ) was similar comparing cognitively intact vs impaired patients undergoing hip fracture repair with spinal anesthesia and sedation . - pubmed
In vitro and in vivo studies in rodent models also indicate a bone - protective role for resveratrol , particularly in ovariectomised rat models that mimic postmenopausal osteoporosis caused by estrogen deficiency . - pubmed
Regular supplementation with 75 mg of resveratrol twice daily has the potential to slow bone loss in the lumbar spine and femoral neck , common fracture sites in postmenopausal women without overt osteoporosis . - pubmed
Patients with miscellaneous risk factors were older ( p<0.01 ) , and had higher rates of hypertension ( p=0.01 ) and hyperlipidaemia ( p=0.04 ) . - pubmed
For SAT1 , SAT2 , and serotype A viruses , the genetic diversity is reflected in antigenic variation , and indications are that vaccine strains may be needed for each topotype . - pubmed
Although the precise mechanism of transmission of FMD from buffalo to cattle is not well understood , it is facilitated by direct contact between these two species . - pubmed
Once cattle are infected they may maintain SAT infections without the further involvement of buffalo . - pubmed
A deep analysis using panel - based next - generation sequencing in an Ecuadorian pediatric patient with anaplastic astrocytoma : a case report . - pubmed
BACKGROUND : Anaplastic astrocytoma is a rare disorder in children from 10 to 14 years of age , with an estimated 0.38 new cases per 100,000 people per year worldwide . - pubmed
Because it has never been genetically studied in the Ecuadorian population , we chose to genetically characterize an Ecuadorian pediatric patient with anaplastic astrocytoma for the first time . - pubmed
The purpose of our study was to compare the safety and effectiveness of MT for patients with tBAO compared to those with non - tandem basilar artery occlusions ( ntBAO ) . - pubmed
RESULTS : A total of 15 patients with tBAO and 74 patients with ntBAO were enrolled . - pubmed
Successful reperfusion ( modified thrombolysis in cerebral infarction score > = 2b ) was obtained in 73.3 % versus 90.5 % ( OR = 0.29 , 95%CI : 0.07 - 1.15 ) , good clinical outcome ( 3 - months modified Rankin scale < = 2 ) was reached by 26.7 % versus 32.4 % ( OR = 0.76 ; 95 % CI : 0.24 - 2.63 ) and mortality at 3 - months was 46.7 % versus 31 % ( OR = 1.94 ; 95%CI : 0.63 - 6 ) of patients with tBAO versus ntBAO , respectively . - pubmed
Two patients ( 13.3 % ) with tBAO and three ( 4 % ) with ntBAO had symptomatic intracranial haemorrhage ( OR = 3.64 ; 95 % CI : 0.55 - 24 ) . - pubmed
CONCLUSION : Mechanical thrombectomy for patients with tandem basilar artery occlusion tends to be associated with lower rates of successful reperfusion and good clinical outcome , and higher rate of mortality . - pubmed
Volunteers aged 7 - 17.9 years without a known history of liver disease were recruited at four sites for a research MRI and blood draw between February 2018 and October 2019 . - pubmed
Conclusion Mean liver stiffness measured with MR elastography in children without liver disease was 2.1 kPa ( similar to that in adults ) . - pubmed
PURPOSE : Patients with advanced esophageal cancer have a poor prognosis and limited treatment options after first - line chemotherapy . - pubmed
PATIENTS AND METHODS : In this open - label , phase III study , we randomly assigned ( 1:1 ) 628 patients with advanced / metastatic squamous cell carcinoma or adenocarcinoma of the esophagus , that progressed after one prior therapy , to pembrolizumab 200 mg every 3 weeks for up to 2 years or chemotherapy ( investigator 's choice of paclitaxel , docetaxel , or irinotecan ) . - pubmed
Median OS was 8.2 months versus 7.1 months ( HR , 0.78 [ 95 % CI , 0.63 to 0.96 ] ; P = .0095 ) in patients with squamous cell carcinoma and 7.1 months versus 7.1 months ( HR , 0.89 [ 95 % CI , 0.75 to 1.05 ] ; P = .0560 ) in all patients . - pubmed
CONCLUSION : Pembrolizumab prolonged OS versus chemotherapy as second - line therapy for advanced esophageal cancer in patients with PD - L1 CPS > = 10 , with fewer treatment - related adverse events . - pubmed
Elevated concentrations of serum phosphate are linked with progression and increased case fatality rate in animals and humans with chronic kidney disease . - pubmed
In rodents , an excess intake of dietary phosphorus combined with an inverse dietary calcium : phosphorus ratio ( < 1 : 1 ) contributes to renal calcification . - pubmed
Renal injury also has occured in cats fed experimental diets supplemented with highly soluble phosphate salts , especially in diets with inverse calcium : phosphorus ratios . - pubmed
No data currently shows that commercial cat foods induce renal injury . - pubmed
A fecal filtrate of human origin containing the Norwalk agent of epidemic viral gastroenteritis was administered by stomach tube to chimpanzees in an attempt to induce diarrheal disease . - pubmed
The availability of the chimpanzee as an experimental animal host susceptible to infection with the Norwalk agent should facilitate the study of epidemic viral gastroenteritis . - pubmed
Prevention of thrombosis in patients on hemodialysis by low - dose aspirin . - pubmed
The study was continued until there were 24 patients with thrombi and both groups had been under observation for a mean of nearly five months . - pubmed
Thrombi occurred in 18 of 25 ( 72 per cent ) of patients given placebo and 16 of 19 ( 32 per cent ) of those given aspirin ( P less than 0.01 ) . - pubmed
The incidence of thrombosis was reduced from 0.46 thrombi per patient month in the placebo group to 0.16 thrombi per patient month in the aspirin group ( p less than 0.005 ) . - pubmed
Pyracetam also facilitates the process of teaching in rats , improves the execution of a developed conditioned avoidance reaction , protects rats against manifestations of retrograde amnesia induced by an electric shock , applied after development of the conditioned reflex of passive avoidance . - pubmed
The prognosis and pathological findings in 44 patients with breast cancer who had taken contraceptive steroids during the year before diagnosis were compared with those in 44 controls matched for age and parity . - pubmed
In patients with axillary node disease the recurrence rate in the controls was significantly higher than in the study group and more of the control patients had died . - pubmed
Ganglioneuromas in hamsters . - pubmed
A description is given of three cases of ganglioneuromas , which originated from ganglia of the sympathetic chain of hamsters . - pubmed
Other reports of such tumors in this species are reviewed and the literature relative to hamster ganglioneuromas presented . - pubmed
Differences were observed in edema - forming , hemorrhage , defibrination , indirect hemolysis , myonecrosis , proteolysis and lethal activity between venoms from different genera or species , as well as according to the geographic area of origin in B. - pubmed
Structure of the granulocyte macrophage colony - stimulating factor gene in patients with the myelodysplastic syndromes . - pubmed
Intimal changes at the prelesional stage of atherosclerotic lesions were investigated ultrastructurally using hamsters fed a high cholesterol diet for 1 day to 1 month . - pubmed
Adult salicylate poisoning : deaths and outcome in patients with high plasma salicylate concentrations . - pubmed
The clinical features , plasma salicylate concentrations , acid - base abnormalities and other biochemical findings are presented for 97 patients who either died from acute salicylate overdosage or survived maximum recorded plasma salicylate concentrations of 700 mg / l or greater . - pubmed
[ 1,2 - Bis ( 2,6 - dichloro-4 - hydroxyphenyl ) ethylenediamine ] dichloro - platinum ( II ) , ( C ) , a platinum complex with endocrine activity and a specific effect on hormone - dependent mammary tumors , was tested for its tumor - inhibitory activity in the hormone - sensitive R 3327 and Nb prostate carcinoma models of the rat and for its endocrine activities in comparison to the ligand L and diethylstilbestrol ( DES ) . - pubmed
Established tumors of the R 3327 prostate tumor were strongly inhibited by C. Its effect equaled that of DES and was significantly better than that of L. Accessory sex organ weights and testosterone levels were strongly reduced by C as well as L. This antigonadotrophic effect , which is almost comparable to DES , was confirmed in 10 day experiments with intact , mature mice and rats , whereas a direct antiandrogenic activity was not given . - pubmed
Pain and the laboratory animal . - pubmed
[ Comparative electrooculographic study of normal subjects and patients with demyelinating disease ] . - pubmed
But recording of auditory evoked potentials is helpful in excluding brain death in certain patients . - pubmed
Oral transfer of biliary immunoglobulins collected from infected rats at various times during a primary infection provided no protection to pups . - pubmed
In one of the patients caseous tuberculosis of the bronchopulmonary , peribronchial and periportal lymph nodes was found , too . - pubmed
In 48 normotensive patients successful analgesia was achieved ; in seven hypertensive patients , four were pain - free , but the other three required more lidocaine to achieve adequate analgesia . - pubmed
Amoxapine for the treatment of psychotically depressed subjects . - pubmed
Factors influencing phenotypic diversity of human prostate carcinoma cells metastasizing in athymic nude mice . - pubmed
Three related human prostate carcinoma cell lines , PC-3 , 1 - LN - PC-3 - 1A ( 1 - LN ) , and 1 - LN - PC-3 - 1A clone 4 ( clone 4 ) were compared in terms of relative metastatic capacity in adult and young male nude mice . - pubmed
Only 1 - LN produced lung metastases after intravenous injection into both 6- to 8 - week - old and 4 - week - old nude mice , as well as in mice injected intraperitoneally . - pubmed
The extent of the phenotypic diversity exhibited by these human prostate tumor lines was influenced by inherent dissemination ability , age of the host , and route of injection . - pubmed
These lines provide a useful system for the analysis of the biology of human tumor metastasis in nude mice . - pubmed
[ Value of studies of color perception thresholds in the diagnosis of partial atrophy of the optic nerve in children ] . - pubmed
Minimal bone marrow damage in mice given bleomycin . - pubmed
[ Prethrombotic condition of patients with hypertensive disease and arteriosclerosis ] . - pubmed
[ Pathological anatomy of encephalic tumors in children ] . - pubmed
Two methods of carrier detection were applied to the siblings of two children with congenital adrenal hyperplasia due to 21 - hydroxylase ( 21 - OH ) deficiency . - pubmed
In the relationship between viruses and cancer , viruses and chronic diseases , or inanimate pathogens like tobacco and lung cancer , we know very little as to the factors that result in clinical disease among the many who are presumably susceptible and fully exposed . - pubmed
Transient focal liver scan defects in children receiving chemotherapy ( pseudometastases ) . - pubmed
Three pediatric patients with tumors ( two rhabdomyosarcoma , one Wilms tumor ) had significant focal defects on Tc-99 m sulfur colloid scans while receiving chemotherapy ( all three had received chemotherapy , including actinomycin D , within ten days prior to scanning ) . - pubmed
The finding of defects on liver scans of pediatric patients receiving chemotherapy must not be automatically assumed to be metastatic disease ; the changes may relate to hepatic response to recently administered chemotherapy . - pubmed
Hepatocytes isolated from livers of rats with various models of acute uremia ( binephrectomy , ureter ligation , uranyl nitrate - induced , or ischemic ARF ) were incubated with glucagon , adrenalin , or cyclic AMP using serine as a substrate . - pubmed
The correlation between glucose concentration and the cytosolic redox state was different in control and sham - operated rats than in either uremic group . - pubmed
This study confirms earlier investigations of a key role of serine in carbohydrate metabolism in acutely uremic rats . - pubmed
A case of a 55 - year old patient is presented with terminal renal insufficiency and a massive prostatic adenoma causing urinary tract obstruction . - pubmed
Twenty - eight patients with inoperable or metastatic gastric cancer were treated with combination chemotherapy using 5 - fluorouracil , adriamycin and mitomycin - C ( FAM ) . - pubmed
Over an eight - year period , 19 ( 7.4 % ) of 257 patients with penetrating trauma had endophthalmitis develop , and 19 ( 31.1 % ) of 61 cases of endophthalmitis were due to trauma . - pubmed
Eleven ( 10.7 % ) of 103 patients with intraocular foreign bodies had endophthalmitis develop . - pubmed
Forty - five hospitalized patients suffering from a moderate to severe nonpsychotic major depressive disorder were clinically subdivided into three groups : endogenous ( n = 20 ) , neurotic ( n = 19 ) , and " ambiguous " ( n = 6 ) . - pubmed
One thousand lines of a balanced lethal strain of Drosophila melanogaster heterozygous at seven allozyme loci were subjected to chronic ( 0.15 rad / min ) gamma - irradiation ( 137Cs ) . - pubmed
In patients with cochlear deafness , this bandwidth is greatly enlarged , ranging from 0.42 - 2.2 octaves . - pubmed
[ Enteric dysentery vaccines and their effectiveness in a rabbit intestinal loop model . - pubmed
The residual virulence of attenuated vaccinal strains of Shigella administered into the intestinal loops ] . - pubmed
sonnei strain , attenuated Sh . - pubmed
This indicates that vaccine strains have insignificant residual virulence and suggests that the intestinal loop models , together with other models , may be used for testing the safety of vaccines prepared from Shigella strains . - pubmed
Genotypic characterization and clinical evaluation of the attenuated A / California / 10 / 78 ( H1N1 ) recombinant strain RIT 4265 . - pubmed
The water proton NMR spin - lattice relaxation time if measured in HEp-2 cells in relation to the infection by different viruses ( Poliovirus type 1 , Coxsackievirus B-3 , human Adenovirus , Measles virus , Respiratory Syncytial virus , Herpes simplex virus , subtype 1 , and Vaccinia virus ) . - pubmed
Also the 74 test persons of the acetyl salicyl acid group and 88 test persons of the control group who remained after subtraction of all deceased and dismissed patients in the semiquantitative judgment of the progression of macroangiopathy ( ischaemic heart disease , chronic venous insufficiency , arterial occlusive disease , vascular calcification ) and in the development of retinopathy no significant differences in the sense of the effect of acetyl salicyl acid expected could be recognized . - pubmed
Controlled neuropsychological investigation of patients with neurotic excoriations . - pubmed
A 57 - year - old man with manifestations of Marfan syndrome was referred for detail examination of cardiac murmur to our hospital . - pubmed
We examined the retinal toxicity and intraocular pharmacokinetics of intravitreal norfloxacin in rabbits . - pubmed
METHODS : Twenty - three albino and 23 pigmented rabbits were divided into three groups to evaluate retinal toxicity and two groups to investigate the intraocular pharmacokinetics . - pubmed
The genetic background of polygenic hypercholesterolemia was studied in hypercholesterolemic children consuming a diet identical to control individuals with low cholesterol concentrations . - pubmed
The effects of exercise and stress on regional and whole body adiposity were examined in an established animal model of diet - induced coronary artery atherosclerosis , the cynomolgus monkey ( Macaca fascicularis ) . - pubmed
A 32 yr old woman presented with intermittent intermenstrual bleeding , 7 mths after a first trimester termination of pregnancy . - pubmed
An additional 19 patients , not coded for shoulder dystocia , sustained 14 fractured clavicles and five brachial plexus injuries . - pubmed
Response of type I atrial fibrillation to atrial pacing in humans . - pubmed
The purpose of this study was to assess the local and left atrial response to pacing at the high right atrium during type I AF in humans . - pubmed
METHODS AND RESULTS : Pacing was performed at the high right atrium during type I AF in 24 patients in the electrophysiology laboratory . - pubmed
Local capture of the right atrium during AF was demonstrated for at least one pacing cycle length in each patient . - pubmed
Prompt volume replacement and diuresis is the cornerstone of therapy in preventing acute renal failure in patients who develop rhabdomyolysis and myoglobinuria . - pubmed
CLINICAL RELEVANCE : Flow cytometric techniques may be useful for detection of prothrombotic disorders in horses . - pubmed
Hypertension was induced in male Sprague - Dawley rats ( n=40 ) by suprarenal aortic coarctation . - pubmed
However , the short chain analogue of the indolinic nitroxide and the quinolinic nitroxide had a negative effect on trout hemolysis , contrary to what has already been observed in previous studies on human RBCs ( red blood cells ) . - pubmed
Elevated lipogenesis is a key determinant of exaggerated fat deposition in adipose tissue of obese Zucker rats . - pubmed
Growth failure is a frequent side effect of long - term high - dose glucocorticoid therapy in children . - pubmed
Poor - grade subarachnoid hemorrhage patients : the use of nimodipine and other optional treatments . - pubmed
The use of calcium antagonists has been advocated as decreasing morbidity and mortality in patients with subarachnoid hemorrhage ( SAH ) following aneurysm rupture . - pubmed
A temporal MRI assessment of neuropathology after transient middle cerebral artery occlusion in the rat : correlations with behavior . - pubmed
The purpose of this study was to evaluate the temporal and spatial pathological alterations within ischemic tissue using serial magnetic resonance imaging ( MRI ) and to determine the extent and duration of functional impairment using objective behavioral tests after transient middle cerebral artery occlusion ( tMCAO ) in the rat . - pubmed
This long - term study is the first of its kind in tracing the dynamic pathologic and functional consequences of tMCAO in the rat . - pubmed
Nowadays , the buffer used is lactate , and its concentration in conventional peritoneal dialysis fluids is 35 or 40 mmol / L. Despite the general thought that peritoneal dialysis adequately corrects uremic acidosis , several studies have demonstrated that more than 50 % of patients present mild to moderate acidosis with the solution containing 35 mmol / L of lactate , although with a 40 mmol / L solution this percentage decreases , a substantial number of patients still remain acidotic . - pubmed
It has been demonstrated that bicarbonate solutions have better biocompatibility than the lactate buffered solution and substantially reduce abdominal discomfort experienced by a certain percentage of patients during the solution infusion . - pubmed
BACKGROUND : Intravenous administration of radiographic contrast agents is an important cause of acute renal failure , accounting for one third of the cases of hospital - acquired acute renal failure in patients with native kidneys . - pubmed
As patients with renal transplantation may be at a higher risk of contrast - induced nephrotoxicity ( CIN ) due to concomitant use of cyclosporine and higher prevalence of diabetes and renal insufficiency , we retrospectively studied development of CIN in these patients . - pubmed
The following were the various ICS done in these patients : coronary angiogram ( 6 ) , CT scan with intravenous contrast ( 11 ) , angiogram for evaluation of peripheral vascular disease ( 11 ) , allograft angiogram with angioplasty ( 5 ) , pulmonary angiogram ( 1 ) and intravenous pyelogram ( 1 ) . - pubmed
Fourty percent of patients ( 14 of 35 ) had diabetes , and 25.7 % ( 9 of 35 ) had chronic rejection . - pubmed
Two of these patients were excluded from the analysis as renal functions in these patients had deteriorated prior to ICS and renal failure was attributed to sepsis . - pubmed
Of the remaining 7 patients , 5 had diabetes and 2 had chronic rejection . - pubmed
Only 4 of these 7 patients with CIN received prophylaxis ( I / V hydration ) prior to ICS . - pubmed
The baseline serum creatinines were not different in patients who had no change in renal function to those who developed CIN ( 1.97 + /- 0.20 vs 1.54 + /- 0.17 mg / dl , p = 1.5 , mean + /- SEM ) . - pubmed
More than 50 % increase in baseline serum creatinine was seen in only 3 of these 7 patients , 2 of these patients had diabetes and third had chronic rejection and congestive heart failure . - pubmed
None of these patients received prophylaxis for CIN . - pubmed
Three patients also had a & gt ; 25 % decrease in baseline serum creatinine after ICS , and all of them had allograft angiography with angioplasty for renal artery stenosis . - pubmed
CONCLUSION : In our retrospective study , the incidence of CIN in renal allograft recipients applying a broader classification of & gt ; or = 25 % increase in baseline serum creatinine was 21.2 % ( 7 of 33 patients ) . - pubmed
The incidence of CIN was lower 15.3 % ( 4 of 26 ) in patients who received intravenous hydration compared to 42.8 % ( 3 of 7 ) in patients who received no prophylaxis prior to ICS . - pubmed
In order to better understand the mechanisms behind the rapid expansion of these strains , the virulence of 10 clinical and two transformed PNSP strains were compared with the virulence of three fully susceptible strains in a mouse model of bacteremia and a rat model of acute otitis media . - pubmed
New rat model that phenotypically resembles autosomal recessive polycystic kidney disease . - pubmed
Numerous murine models of polycystic kidney disease ( PKD ) have been described . - pubmed
While mouse models are particularly well suited for investigating the molecular pathogenesis of PKD , rats are well established as an experimental model of renal physiologic processes . - pubmed
Han : SPRD - CY : rats have been proposed as a model for human autosomal dominant PKD . - pubmed
In the mutants , the renal cystic phenotype resembles human autosomal recessive PKD ( ARPKD ) . - pubmed
It is concluded that the clinical and renal histopathologic features of this new rat model strongly resemble those of human ARPKD . - pubmed
We report a 56 - year - old woman with this disorder who presented unusually with respiratory failure and who initially had absent responses to phrenic nerve stimulation bilaterally . - pubmed
The mechanism of the patient 's respiratory failure may have been chronic conduction blocks in the phrenic nerves leading to diaphragmatic weakness . - pubmed
When DNA mismatch repair fails , the result is a mutator phenotype , which can lead to cancer in humans . - pubmed
The indices of local nonspecific lung protection in the bronchoalveolar lavage fluid and cells were studied in 20 patients with acute pneumonia and 20 patients with lingering pneumonia . - pubmed
In the patients with lingering pneumonias who underwent a course of conventional therapy , these indices fail to recover to a greater extent , neutrophilic lung remained high . - pubmed
Fifteen cases of children with congenital nasal pyriform aperture stenosis were reviewed for presentation of the disorder , management , and effectiveness of treatment , making it the largest series to date . - pubmed
Preoperative symptoms of upper airway obstruction were improved in all patients at an average follow - up of 2.4 years ( range , 1 month to 5 years ) . - pubmed
We report a case of a patient with symptomatic pacemaker - mediated tachycardia ( PMT ) . - pubmed
PMT should be suspected when asynchronous pacing induced by magnet application causes temporary resolution of an unknown tachycardia in a patient with a pacemaker . - pubmed
We present recent advances in our understanding of cellular patterns in the vertebrate retina and the mechanisms that underlie their assembly , the ability of adult anamniote retinas to regenerate following injury , and how these seemingly disparate topics can be successfully merged into an effort to better understand both processes . - pubmed
After administering a single intraperitoneal injection of streptozotocin ( 60 mg / kg ) to Sprague - Dawley rats and ensuring the induction of diabetes at the end of 24 h , celecoxib was administered b.i.d . - pubmed
Furthermore , the retinal vascular leakage estimated as vitreous to plasma protein ratio increased in diabetic animals from 0.35+/-0.1 to 1.1+/-0.1 and celecoxib treatment significantly decreased this ratio to 0.4+/-0.1 . - pubmed
Deficits in PPI have been repeatedly reported in patients with schizophrenia or other psychiatric disorders characterized by abnormalities in sensory , cognitive , or motor gating . - pubmed
Because some forms of schizophrenia appear to be attributable to early developmental perturbations , many animal studies have examined the influences of various developmental manipulations on PPI in adulthood . - pubmed
Thus , social isolation rearing of rats provides a developmentally specific , non - pharmacological manipulation that leads to deficits in sensorimotor gating that mimic those observed in schizophrenia patients and are responsive to antipsychotic medications . - pubmed
In the present study , we investigated whether SU5416 could augment cisplatin - induced cytotoxicity in human ovarian cancer cells . - pubmed
The fistula completely healed in 15 surgically treated patients ( 17.4 % ) and 71 conservatively treated patients ( 82.6 % ) , and in the follow - up observation , recurrence was identified in none of the cases . - pubmed
The antiinflammatory effect of the methanol extract of the leaves of Bambusa arundinacea against carrageenin - induced as well as immunologically induced paw oedema and also its antiulcer activity in albino rats have been studied and found to be significant when compared to the standard drugs . - pubmed
Thus , the combination of herbal product ( methanol extract of Bambusa arundinacea ) with modern medicine ( NSAIAs ) will produce the best antiinflammatory drug and will be useful for long - term treatment of chronic inflammatory conditions like rheumatoid arthritis with peptic ulcer , which are common . - pubmed
Nutritional factors and the production by dietary choline deficiency of cancer de novo in mice . - pubmed
[ Distribution of endovenous Fe55 and Fe59 in ferro - proteins in normal rabbits and those on a myopathic diet ] . - pubmed
Comparison of immunities against tuberculosis between the guinea pigs treated with dead tubercle bacilli paraffin - oil vaccine and those treated with BCG , by the method of slide cell culture . - pubmed
Inhibition of the human enzyme is a possible strategy for the treatment of bone - resorptive diseases such as osteoporosis . - pubmed
Characterization of blood pressure and morphological traits in cardiovascular - related organs in 13 different inbred mouse strains . - pubmed
, systolic blood pressure , weight ( corrected by body weight ) of several cardiac compartments and adrenals and kidneys , and histological correlates for kidneys and adrenals ] in male and female mice from 13 different inbred strains . - pubmed
We selected strains so that each major genealogical group would be represented and to conform to priorities set by the Mouse Phenome Database project . - pubmed
For instance , female AKR / J mice had relatively higher body weight and systolic blood pressure values than their male counterparts , perhaps constituting an animal model of the metabolic X syndrome . - pubmed
RESULTS : In 33 patients with pregnancy - induced hypertension and in five patients with exacerbation of preexisting hypertension in pregnancy no point mutations were found at codon 810 in exon 6 . - pubmed
Association of timing , duration , and intensity of hyperglycemia with intensive care unit mortality in critically ill children . - pubmed
OBJECTIVE : To study the association of timing , duration , and intensity of hyperglycemia with pediatric intensive care unit ( PICU ) mortality in critically ill children . - pubmed
PATIENTS : A total of 152 critically ill children receiving vasoactive infusions or mechanical ventilation . - pubmed
CONCLUSIONS : Hyperglycemia is common in critically ill children . - pubmed
A prospective , randomized trial of strict glycemic control in this subset of critically ill children who are at high risk of mortality is both warranted and feasible . - pubmed
SUBJECTS AND METHODS : The study group was comprised of 50 consecutive patients diagnosed with schizophrenia , 18 years of age and older attending the out - patient clinic of the Mental Health Center in Beer - Sheva , Israel . - pubmed
PATIENT(S ): A 22 - year - old woman with TAR syndrome referred to our department with primary amenorrhea . - pubmed
Breast - feeding is a route of HIV transmission from an HIV infected mother to her infant . - pubmed
HIV / AIDS reference questions in an AIDS service organization special library . - pubmed
RESULTS : Classification of AF in these discharged patients included 74 ( 55 % ) with first - detected episode ; 28 ( 21 % ) with recurrent paroxysmal AF ; 17 ( 13 % ) with recurrent persistent AF ; and 16 ( 12 % ) with permanent AF . - pubmed
BACKGROUND : Reconstitution of immune function during potent antiretroviral therapy can prompt discontinuation of maintenance cytomegalovirus ( CMV ) therapy but has also been associated with sight - threatening inflammatory conditions including immune recovery uveitis ( IRU ) . - pubmed
Six participants in Group 1 and 3 participants in Group 2 developed IRU on - study . - pubmed
METHODS : We conducted a prospective study of 18 subjects with unilateral Meniere ' s disease treated with intratympanic gentamicin injection and followed all subjects for 1 year . - pubmed
RESULTS : During the follow - up period , 11 subjects ( " single - treatment group " ; 61 % ) had control of their vertigo with a single gentamicin injection . - pubmed
The remaining 7 subjects ( " multiple - treatment group " ; 39 % ) experienced recurrent vertigo that required a second injection of gentamicin at a mean of 6 months after the first treatment . - pubmed
The 11 subjects in the single - treatment group had significantly greater reduction of labyrinthine function after the first treatment , as measured by change in ipsilateral horizontal canal gain , than did the 7 subjects with vertigo recurrence . - pubmed
PURPOSE OF REVIEW : As the most common arthritis and a leading cause of chronic disability , osteoarthritis is associated with substantial cost to the individual and to society . - pubmed
ND virus ( NDV ) is the only member of the avian paramyxovirus serotype 1 ( APMV1 ) causing ND outbreak in bird flocks . - pubmed
Here , we describe an effective and unprecedented method for detecting NDV strains of all pathotypes . - pubmed
Patients ( n=530 ) were prospectively categorized into defined melanoma risk groups and followed by clinical and epiluminescence microscopy ( ELM ) examinations . - pubmed
A 39 - year - old man was scheduled for removal of right adrenal tumor . - pubmed
We observed cytotoxic effects using drug concentrations corresponding to blood plasma levels achieved in NB patients . - pubmed
BACKGROUND : Lumbar supports are used in the treatment of low back pain patients to make the impairment and disability vanish or decrease . - pubmed
AIMS / HYPOTHESIS : To assess thiamine status by analysis of plasma , erythrocytes and urine in type 1 and type 2 diabetic patients and links to markers of vascular dysfunction . - pubmed
METHODS : Diabetic patients ( 26 type 1 and 48 type 2 ) with and without microalbuminuria and 20 normal healthy control volunteers were recruited . - pubmed
RESULTS : Plasma thiamine concentration was decreased 76 % in type 1 diabetic patients and 75 % in type 2 diabetic patients : normal volunteers 64.1 ( 95 % CI 58.5 - 69.7 ) nmol / l , type 1 diabetes 15.3 ( 95 % CI 11.5 - 19.1 ) nmol / l , p & lt ; 0.001 , and type 2 diabetes 16.3 ( 95 % CI 13.0 - 9.6 ) nmol / l , p & lt ; 0.001 . - pubmed
Renal clearance of thiamine was increased 24 - fold in type 1 diabetic patients and 16 - fold in type 2 diabetic patients . - pubmed
CONCLUSIONS / INTERPRETATION : Low plasma thiamine concentration is prevalent in patients with type 1 and type 2 diabetes , associated with increased thiamine clearance . - pubmed
OBJECT : To determine the prevalence and incidence of Staphylococcus aureus strains among preschool- and school - aged pupils and susceptibility of these strains to antimicrobial materials . - pubmed
The isolated Staphylococcus aureus strains were tested for resistance to methicillin by performing disc diffusion method using commercial discs ( Oxoid ) ( methicillin 5 microg per disk and oxacillin 1 microg per disk ) . - pubmed
RESULTS : A total of 292 ( 53.8 % ) Staphylococcus aureus strains were isolated and identified ( 113 ( 46.5 % ) from preschool- and 179 ( 59.7 % ) from school - aged pupils ) . - pubmed
Six methicillin - resistant Staphylococcus aureus strains were isolated : two ( 1.8 % ) of them were from preschool - aged and four ( 2.2 % ) from school - aged pupils . - pubmed
METHODS : Twelve elderly volunteers ( mean age : 65.6+/-6.3 years ) were evaluated for pain ( on a visual analogue scale , [ VAS ] ) , static balance ( as measured by the centre of foot pressure , [ COP ] ) and dynamic balance ( the " Timed Up and Go " [ TUG ] test ) . - pubmed
In this paper , the case of a 58 - year - old woman with an amyloid tumor of the breast , which developed secondary to long - standing rheumatoid arthritis , is presented . - pubmed
The studies provide weak evidence that photosensitizing plants can be effective in conjunction with phototherapy , and moderate evidence that Ginkgo biloba monotherapy can be useful for vitiligo . - pubmed
BACKGROUND : Increased oxidative stress is associated with various complications in hemodialysis ( HD ) patients . - pubmed
METHODS : We examined the effect of coenzyme Q10 ( CoQ10 ) administration on the plasma oxidative products and antioxidant capacity in 36 HD patients for 6 months . - pubmed
RESULTS : The advanced oxidation protein products ( AOPP ) , malondialdehyde and the percentage of ubiquinone in total CoQ10 were significantly higher in HD patients than in healthy subjects before administration ( 0 month ) . - pubmed
Oxygen radical absorbing capacity ( ORAC ) and Trolox equivalent antioxidant capacity ( TEAC ) , indicators of total antioxidant capacity , were also paradoxically higher in the HD patients at 0 month . - pubmed
CONCLUSION : The CoQ10 administration was partially effective for suppressing the oxidative stress in HD patients . - pubmed
concurrent natural infections in Zambian cattle , based on egg and worm counts . - pubmed
infections while 32 % had F. - pubmed
In particular , data show that obesity in human populations is associated with cognitive decline and enhanced vulnerability to brain injury , while experimental studies in animal models confirm a profile of heightened vulnerability and decreased cognitive function . - pubmed
This review will describe findings from human and animal studies to summarize current understanding of how obesity affects the brain . - pubmed
Thus , enhanced understanding of the effects of obesity and obesity - related metabolic dysfunction on the brain are especially critical as increasing numbers of obese individuals approach advanced age . - pubmed
The chondrodystrophic canine , another sub - species on the other hand are almost totally devoid of notochordal cells and they develop DDD profoundly and early . - pubmed
Children at risk for developmental coordination disorder : judgement of changes in action capabilities . - pubmed
In three separate manipulations , a group of children at risk for developmental coordination disorder ( DCD ; five males , seven females ; mean age 11y 6mo [ SD 6.8mo ] who were at or below the 15th centile on the Movement ABC ) and a group of typically developing children ( TDC ; seven males , five females ; mean age 11y 3mo [ SD 6.8mo ] ) judged the limit of their standing horizontal reach ( HRmax ) under two conditions in which actual HRmax differed . - pubmed
Nicotianamine and histidine / proline are , respectively , the most important copper chelators in xylem sap of Brassica carinata under conditions of copper deficiency and excess . - pubmed
The aim of the present study was to investigate the in vitro effects of 20 metal compounds using rabbit ejaculated spermatozoa as a study model for spermiotoxicity . - pubmed
Eleven patients were operated on for nonunions of the distal phalanx . - pubmed
Three patients had developed infection and four of them had bone resorption after their initial treatments , which probably caused nonunion . - pubmed
One patient had a haematoma formation at the donor site . - pubmed
BACKGROUND : Endoscopic thoracic sympathectomy ( ETS ) was overused for treating patients with hyperhidrosis in Taiwan . - pubmed
METHODS : We invited all surgeons in Taiwan who performed five or more ETSs per year for treating patients with hyperhidrosis to join this study . - pubmed
They agreed that observation or topical therapy was appropriate for patients with mild palmar hyperhidrosis , whereas ETS was appropriate for children , adolescents , and young and middle - aged adults who had severe symptoms . - pubmed
CONCLUSION : Evidence - based consensus development is helpful in decreasing overuse of ETS in treating patients with hyperhidrosis in Taiwan . - pubmed
Cyclophosphamide - induced cardiotoxicity occurred , even though the patient had both shown normal cardiac function before high - dose chemotherapy and had received a lower dose of cyclophosphamide . - pubmed
We describe our management of high - grade car tire foot injuries in children with free anterolateral thigh flap ( ALT ) . - pubmed
Minor gait abnormalities were detected in two of the patients . - pubmed
CONCLUSION : With minimal donor site morbidity , long vascular pedicle allowing anastomosis outside of the trauma zone , we believe free ALT flap provides the ideal soft tissue reconstruction for high grade car tire injuries of foot in children . - pubmed
CATCH : a clinical decision rule for the use of computed tomography in children with minor head injury . - pubmed
We aimed to develop a highly sensitive clinical decision rule for the use of CT in children with minor head injury . - pubmed
METHODS : For this multicentre cohort study , we enrolled consecutive children with blunt head trauma presenting with a score of 13 - 15 on the Glasgow Coma Scale and loss of consciousness , amnesia , disorientation , persistent vomiting or irritability . - pubmed
Once the decision rule has been prospectively validated , it has the potential to standardize and improve the use of CT for children with minor head injury . - pubmed
Extrahippocampal gray matter loss and hippocampal deafferentation in patients with temporal lobe epilepsy . - pubmed
METHODS : Three different MRI studies were performed involving 23 patients with unilateral MTLE ( 8 left and 15 right ) and 34 healthy controls : ( 1 ) voxel - based morphometry ( VBM ) , ( 2 ) diffusion tensor imaging ( DTI ) and ( 3 ) probabilistic tractography ( PT ) . - pubmed
There was a decrease in hippocampal PT in patients with MTLE in limbic areas . - pubmed
Arthropod - borne viruses ( arboviruses ) are a significant cause of human and animal disease worldwide . - pubmed
The molecular biological methods revealed that these strains differ from P. - pubmed
In the present study , the complete genomic sequences of 9 DuCV strains , which were obtained by PCR screening from 90 dead or diseased ducks collected from different regions in China between 2008 and 2010 , were determined and compared with previously available DuCV sequences in public databases . - pubmed
DATA SYNTHESIS : The prevalence of visual impairment in children 5 years of age and younger is between 7 % and 8 % . - pubmed
Treating children younger than age years who have cataracts or strabismus may prevent the development of amblyopia . - pubmed
It is unclear whether treating young children with refractive errors associated with amblyopia would prevent the development of amblyopia . - pubmed
Although early intervention is important for the prevention or treatment of visual impairment , treatment of certain refractive errors in children younger than age 3 years may interfere with the development of the eye . - pubmed
Astrocytes form a significant constituent of seizure foci in the human brain . - pubmed
This article reviews the information now available on the role of astrocytes in the hippocampal seizure focus in patients with temporal lobe epilepsy with hippocampal sclerosis . - pubmed
METHODS : Population - based study including 1388 participants ( 704 women ) older than 18 years in which 300 were untreated hypertensive patients . - pubmed
In 335 untreated hypertensive patients referred to one hypertension clinic , the study was replicated . - pubmed
Loss of basement membrane integrity in human gingival overgrowth . - pubmed
Here we experimentally evaluate whether increased degradation of the basement membrane and apparent invasion of the underlying stroma by epithelial cells could be observed in human gingival overgrowth tissues . - pubmed
Tissues from 20 different individuals with human gingival overgrowth and 15 non - overgrowth samples were evaluated by histological analyses and by immunohistochemistry assays of basement membrane proteins . - pubmed
Tasmanian devils ( Sarcophilus harrisii ) are on the verge of extinction due to a transmissible cancer , devil facial tumour disease ( DFTD ) . - pubmed
There was no significant difference in deaths in hyper- and holoendemic areas , risk difference +1.93 per 1000 children ( 95 % CI -1.78 to 5.64 , 13 trials , 17,898 children ) . - pubmed
[ Impact of age on treatment and outcomes after acute myocardial infarction , particularly in very elderly patients ] . - pubmed
OBJECTIVES : To evaluate the presentation and treatment of myocardial infarction according to age , particularly in very elderly patients . - pubmed
METHODS : We studied 1242 consecutive patients admitted with acute myocardial infarction , assessing in - hospital , 30 - day and one - year mortality during follow - up for each age - group . - pubmed
RESULTS : Elderly patients had a worse risk profile ( except for smoking ) , more previous history of coronary disease and a worse profile on admission , with the exception of lipid profile , which was more favorable . - pubmed
CONCLUSIONS : Elderly patients represent a substantial proportion of the population admitted with myocardial infarction , and receive less evidenced - based therapy . - pubmed
Wistar rats were subjected to 5 , 10 and 20 mg / kg GB daily for 5 days , intraperitoneally , following TBI . - pubmed
Rats were sacrificed at hour 2 , 6 and 12 , as well as day 1 , 2 , 3 and 5 after TBI . - pubmed
For that purpose cancer cells were injected into mice and resulting hybridomas were screened for their ability to inhibit cell proliferation in vitro . - pubmed
The influence of the location of the lesion on the absolute risk of the development of skin cancer in a patient with actinic keratosis . - pubmed
OBJECT : The authors retrospectively reviewed the efficacy and safety of Gamma Knife surgery ( GKS ) in patients with brainstem cavernous malformations ( CMs ) . - pubmed
METHODS : Between 1993 and 2010 , 49 patients with symptomatic CMs were treated by GKS . - pubmed
All 49 patients experienced at least 2 instances of repeated bleeding before GKS ; these hemorrhages caused neurological deficits including cranial nerve deficits , hemiparesis , hemisensory deficits , spasticity , chorea or athetosis , and consciousness disturbance . - pubmed
The pre - GKS annual hemorrhage rate was 31.3 % ( 69 symptomatic hemorrhages during a total of 220.3 patient - years ) . - pubmed
In this study of 49 patients , symptomatic radiation - induced complications developed in only 2 patients ( 4.1 % ; cyst formation in 1 patient and perifocal edema with neurological deficits in the other patient ) . - pubmed
CONCLUSION : Not only supine hemodynamics , but also responses to head - up tilt differed between normotensive and hypertensive patients , indicating functional alterations beyond increased vascular resistance and higher arterial stiffness in hypertension . - pubmed
We present the results of a wild bird surveillance system for A / H5N1 and other avian influenza viruses based on avian fecal sampling in Kenya . - pubmed
An electronic communication system for amyotrophic lateral sclerosis patients - biomed 2013 . - pubmed
A prospective evaluation of hemodynamic management in acute spinal cord injury patients . - pubmed
STUDY DESIGN : Prospective observational study of acute spinal cord - injured ( SCI ) patients . - pubmed
OBJECTIVES : To determine how effectively mean arterial blood pressure ( MAP ) and spinal cord perfusion pressure ( SCPP ) are maintained at target levels in acute SCI patients . - pubmed
METHODS : Twenty - one individuals with cervical or thoracic SCI were enrolled within 48 h of injury . - pubmed
Caffeic acid phenethyl amide improves glucose homeostasis and attenuates the progression of vascular dysfunction in Streptozotocin - induced diabetic rats . - pubmed
BACKGROUND : Glucose intolerance and cardiovascular complications are major symptoms in patients with diabetes . - pubmed
Many therapies have proven beneficial in treating diabetes in animals by protecting the cardiovascular system and increasing glucose utilization . - pubmed
In this study , we evaluated the effects of caffeic acid phenethyl amide ( CAPA ) on glucose homeostasis and vascular function in streptozotocin ( STZ)-induced type 1 diabetic rats . - pubmed
METHODS : Diabetes ( blood glucose levels & gt ; 350 mg / dL ) , was induced in Wistar rats by a single intravenous injection of 60 mg / kg STZ . - pubmed
Hypoglycemic effects were then assessed in normal and type 1 diabetic rats . - pubmed
RESULTS : Oral administration of 0.1 mg / kg CAPA decreased plasma glucose in normal ( 32.9 + - 2.3 % decrease , P & lt ; 0.05 ) and diabetic rats ( 11.8 + - 5.5 % decrease , P & lt ; 0.05 ) . - pubmed
CONCLUSIONS : CAPA induced hypoglycemic activity , increased coronary blood flow and vascular response to phenylephrine in type 1 diabetic rats . - pubmed
CLINICAL RELEVANCE : These results encourage further studies on the potential use of these blue light - mediated auto - photosensitization processes in the treatment of periodontitis for the successful inactivation of Aggregatibacter actinomycetemcomitans . - pubmed
CONCLUSIONS AND RELEVANCE : A thicker cortex associated with a high importance of religion or spirituality may confer resilience to the development of depressive illness in individuals at high familial risk for major depression , possibly by expanding a cortical reserve that counters to some extent the vulnerability that cortical thinning poses for developing familial depressive illness . - pubmed
Clinical outcome and prognostic factors of patients with hepatocellular carcinoma and extrahepatic metastasis treated with sorafenib . - pubmed
METHODS : Sixty - one HCC patients with extrahepatic metastasis who were treated with sorafenib were enrolled in this retrospective cohort study . - pubmed
Intrahepatic tumor stage before treatment allows stratification of prognosis of patients treated with sorafenib . - pubmed
Among the progressive disease group , patients with T0 - 2 intrahepatic tumor stage had better prognosis than patients with T3 - 4 . - pubmed
CONCLUSION : In HCC patients with extrahepatic metastasis who are treated with sorafenib , intrahepatic tumor stage was a significant and independent prognostic factor . - pubmed
Although the mechanisms underlying osmoregulatory defects in individual patients are presumably diverse , we hypothesize that treatment responses and patient outcomes will vary according to SIAD subtype . - pubmed
Human Bocavirus in Iranian children with acute gastroenteritis . - pubmed
The present study was aimed to determine the prevalence of HBoV in children with gastroenteritis . - pubmed
Human Bocavirus positive samplesfrom patients aged between 1 to 5 years with acute gastroenteritis infection suggest a minor role of HBoVin gastroenteritis ( p=0.0001 ) . - pubmed
CONCLUSION : The study showed a high prevalence of human Bocavirus in young children with acute gastroenteritisdiseases in Iran , suggesting that HBoV play a role in the pathogenesis of gastroenteritis . - pubmed
Evaluation of gabapentin in management of hot flushes in postmenopausal women . - pubmed
This study was conducted to assess the efficacy of gabapentin in controlling hot flushes in postmenopausal women . - pubmed
Fifty postmenopausal patients with hot flushes were randomized in two groups , one receiving gabapentin 900 mg daily along with calcium and another group receiving calcium alone . - pubmed
Recurrent arterial aneurysm rupture of the upper extremity in a patient with vascular - type Ehlers - Danlos syndrome . - pubmed
Arterial aneurysm rupture is one of the most critical complications in patients with vascular - type Ehlers - Danlos syndrome ( vEDS ) . - pubmed
A 38 - year old woman who underwent brachial artery ligation for a ruptured aneurysm was diagnosed postoperatively with vEDS . - pubmed
Given that arterial rupture can occur repeatedly in patients with vEDS , careful life - long follow - up is necessary . - pubmed
MATERIALS AND METHODS : A hyperuricemic animal model was created by administering adenine and allantoxanic acid potassium salt to mice . - pubmed
( Campanulaceae ) has a long history of use as a traditional herbal medicine for the treatments of cough , phlegm , sore throat , lung abscess , chest pain , dysuria , and dysentery . - pubmed
BACKGROUND : Patients with or at high risk of cardiovascular disease have a poor functional capacity ; however , the influence of association among intermittent claudication ( IC ) , abnormal ankle - brachial index ( ABI ) , and physical activity level on functional capacity of these patients has not been fully studied . - pubmed
PATIENTS AND METHODS : This was a prospective cross - sectional study in which 162 consecutive patients were evaluated and classified into three groups according to their ABI : normal ABI ( n=104 , values between 1.00 and 1.40 ) ; borderline PAD ( n=23 , values between 0.91 and 1.00 ) ; and patients with PAD ( n=35 , & lt;=0.90 ) . - pubmed
Here , we studied the efficacy and safety of prolonged - release melatonin ( PRM ) , a registered drug for insomnia , for sleep disorders in totally blind subjects living in normal social environments . - pubmed
CONCLUSION : Nightly use of PRM may potentially improve patient - reported sleep difficulties in totally blind individuals trying to adhere to normal social lifestyle . - pubmed
A randomized , double - blind , phase 2 study evaluating the safety and efficacy of AMG 416 for the treatment of secondary hyperparathyroidism in hemodialysis patients . - pubmed
CONCLUSIONS : The present clinical findings support the continued development of AMG 416 as a treatment for SHPT in hemodialysis patients . - pubmed
The pathogenetic mechanism of AU is still poorly defined , given its remarkable heterogeneity and the many discrepancies between experimental and human uveitis . - pubmed
Current guidelines recommend corticosteroids as the first - line therapy for patients with active AU . - pubmed
Metabolomic Study on the Preventive Effect of Patrinia scabiosaefolia Fisch on Multipathogen Induced Pelvic Inflammatory Disease in Rats . - pubmed
Sixteen differentiating metabolites contributed to the alteration of metabolic profile in PID rats , including two amino acids , three fat acids , nine organic acids , and two types of sugars . - pubmed
Abdominal radiography and ultrasonography are commonly used as part of the initial diagnostic plan for cats with nonspecific signs of abdominal disease . - pubmed
We thus hypothesized that fructose intake by hypertensive rats would have a worse prognosis in developing metabolic disorder and non - alcoholic fatty liver disease . - pubmed
Also , insulin resistance was observed in normotensive and mostly in hypertensive rats after fructose intake . - pubmed
However , we found that fructose intake significantly increased abdominal fat mass deposition in normotensive but not in hypertensive rats . - pubmed
Nevertheless , chronic fructose intake only increased fat deposition and fibrosis in the liver in hypertensive rats . - pubmed
CONCLUSIONS : We demonstrated that , in normotensive and hypertensive rats , fructose intake increased triglycerides and abdominal fat deposition , and caused insulin resistance . - pubmed
However , hypertensive rats that underwent fructose intake also developed interstitial fat deposition and fibrosis in liver . - pubmed
Azole Resistance of Aspergillus fumigatus in Immunocompromised Patients with Invasive Aspergillosis . - pubmed
Multimodality imaging not only allows diagnosis , characterization , and localization of vascular abnormalities but also permits evaluation of natural history and complications , thus , facilitating optimal patient management . - pubmed
Morphologically , one of these strains corresponded to Gephyrocapsa ericsonii and the four others to Reticulofenestra parvula . - pubmed
Ribosomal gene sequences were near identical between these new strains , but divergent from G. - pubmed
Slow acetylators have a higher risk of development of drug - induced toxicity , while fast acetylators and immune - deficient patients face lower treatment success rates . - pubmed
Importantly , tumor cells in 3D culture showed chemotherapy resistance patterns similar to those observed in glioma patients . - pubmed
As [ Saccharicrinis ] marinus Y11 T clustered phylogenetically with strain HQYD1 T , we also propose [ Saccharicrinis ] marinus Y11 T be reclassified as Labilibacter marinus comb . - pubmed
Non - curative surgery for patients with gastric cancer with local peritoneal metastasis : A retrospective cohort study . - pubmed
This study aimed to evaluate the efficacy of non - curative resectional surgery for patients with GC with local peritoneal metastasis . - pubmed
We reviewed the medical records of 47 patients with GC with local peritoneal metastasis , which was found by laparotomy or laparoscopy . - pubmed
The Kaplan - Meier survival curves revealed that resection group had longer survival than non - resection group ( P & lt ; 0.001).Non - curative resectional surgery helps prolong survival time and improve the quality of life for patients with GC with local peritoneal metastasis . - pubmed
The incidence and prognosis of FNP after SSIAC in 381 patients with oral cancer ( 133 with catheterization of the MA , 248 without ) was investigated retrospectively . - pubmed
Only three patients ( two male and one female ) had FNP , for an incidence of 0.8 % . - pubmed
All patients with FNP had undergone catheterization of the MA , and the incidence of FNP in this group was 2.3 % ( 3/133 ) . - pubmed
One of the three patients with FNP had paralysis of the third branch of the trigeminal nerve . - pubmed
Because the administration of anticancer agents via the MA or MMA carries a risk of FNP , this information will be useful when obtaining informed consent from patients before treatment . - pubmed
METHODS : The sample included 40 male schizophrenic patients with and 40 male schizophrenic patients without substance use disorder comorbidity who had applied to Ankara Numune Research and Training Hospital . - pubmed
Our goals were to identify risk factors associated with regional recurrence and to determine whether a radiosensitivity index ( RSI ) gene expression signature ( GES ) could identify patients who experience a survival benefit with regional RT . - pubmed
Postoperative regional RT was associated with a reduced risk of regional recurrence among all patients on univariate ( 5 - year estimate : 95.0 % vs 83.3 % ; P=.036 ) and multivariate analysis ( hazard ratio[HR ] , 0.15 ; 95 % CI , 0.05 - 0.43 ; P<.001 ) . - pubmed
Among higher - risk subgroups , regional RT was associated with a lower risk of regional recurrence among patients with clinically detected lymph nodes ( n=175 ; 5 - year regional control : 94.1 % vs 69.5 % ; P=.003 ) and extracapsular extension ( ECE ) present ( n=138 ; 5 - year regional control : 96.7 % vs 62.2 % ; P<.001 ) . - pubmed
Among a subset of radiated patients with gene expression data available , a low RSI GES ( radiosensitive ) tumor status was associated with improved survival compared with a high RSI GES ( 5 - year : 75 % vs 0 % ; HR , 10.68 ; 95 % CI , 1.24 - 92.14 ) . - pubmed
Conclusions : Regional RT was associated with a reduced risk of regional recurrence among patients with ECE and clinically detected nodal disease . - pubmed
Oral administration of red ginseng powder fermented with probiotic alleviates the severity of dextran - sulfate sodium - induced colitis in a mouse model . - pubmed
In order to produce homogeneously effective red ginseng , we prepared probiotic - fermented red ginseng and evaluated its activity using a dextran sulfate sodium ( DSS)-induced colitis model in mice . - pubmed
Initial analysis of intestinal damage indicated that the administration of probiotic - fermented red ginseng significantly decreased the severity of colitis , compared with the control and the activity was higher than that induced by oral administration of ginseng powder or probiotics only . - pubmed
Collectively , oral administration of probiotic - fermented red ginseng reduced the severity of colitis in a mouse model , suggesting that it can be used as a uniformly effective red ginseng product . - pubmed
OBJECTIVE : To evaluate the long - term clinical and imaging efficacy of etanercept in patients with early , active nonradiographic axial spondyloarthritis ( SpA ) . - pubmed
METHODS : Adult patients who satisfied the Assessment of SpondyloArthritis international Society ( ASAS ) classification criteria for axial SpA ( but not the modified New York radiographic criteria ) , with symptom duration & gt;3 months to & lt;5 years , and who were unresponsive to & gt;=2 nonsteroidal antirheumatic drugs ( NSAIDs ) received double - blind etanercept 50 mg / week or placebo for 12 weeks , followed by open - label etanercept 50 mg / week to week 104 . - pubmed
At week 104 , 61 of 81 ( 75 % ) , 49 of 81 ( 61 % ) , 48 of 80 ( 60 % ) , and 57 of 81 ( 70 % ) patients who received etanercept throughout the trial achieved ASAS20 , ASAS40 , Ankylosing Spondylitis Disease Activity Score ( ASDAS ) inactive disease , and Bath Ankylosing Spondylitis Disease Activity Index criteria for 50 % improvement ( BASDAI 50 ) scores , respectively ( observed ) . - pubmed
CONCLUSION : Patients with early , active nonradiographic axial SpA and an inadequate response to at least 2 NSAIDs demonstrated improvement in clinical and imaging outcomes that were sustained through 104 weeks of etanercept treatment . - pubmed
Preterm birth continues to be a significant global health care issue , due to our lack of understanding of the mechanisms that drive human labour and delivery . - pubmed
Study of gefitinib maintenance in unselected patients with metastatic primary lung adenocarcinoma : A descriptive study . - pubmed
BACKGROUND : Maintenance treatment of patients with advanced nonsmall cell lung cancer ( NSCLC ) without disease progression after first - line chemotherapy is a subject of ongoing research . - pubmed
The major toxicity observed was rash / acne in 15 patients , pruritus in 7 patients , and one patient had Grade 4 pneumonitis . - pubmed
RESULTS : 14,290 patients were identified , 1294 ( 9.1 % ) developed IH , 48 % within 1 - year , 33 % at 1 - 2 years , and 19 % at 2 - 3 years post - surgery . - pubmed
Retinal detachment stabilizes during physical protection and posturing but progresses through bodily activity and during interruptions in patients with macula - on retinal detachment . - pubmed
Retrospective observational cohort study on cosmetic outcome of using Ti - Ni memory alloy wire for intradermal suture following mastectomy in patients with breast cancer . - pubmed
The method of suturing for incisions is crucial for the comprehensive treatment of clinical patients with breast cancer . - pubmed
Furthermore , the mean number of days of wound healing was significantly decreased for the active group compared with that for the control group ( P=0.0026 ) in the patients with diabetes . - pubmed
In addition , the usage of Ti - Ni memory alloy wire was able to decrease the mean number of wound healing days between patients with diabetes and their non - diabetic counterparts ( P=0.7009 ) . - pubmed
This technique may be useful for preventing scar overgrowth and for facilitating the recovery process in patients with diabetes . - pubmed
Ten - year survival was worse in patients & lt ; 65 years old ( p = 0.035 ) , in those with BMI & gt ; 30 ( p = 0.017 ) and in those with postoperative increases in medial tibial sclerosis ( p & lt ; 0.001 log - rank ) . - pubmed
METHODS : This prospective , non - randomized , controlled study involved patients who had cataract surgery with bilateral implantation of bifocal or trifocal IOLs . - pubmed
The near , intermediate , and distance visual acuities , defocus curve , optical quality including modulation transfer functions and higher - order aberrations , National Eye Institute Visual Functioning Questionnaire-14 , patient satisfaction , spectacle independence , and perception of visual disturbances were assessed in all patients . - pubmed
Craving Responses to Methamphetamine and Sexual Visual Cues in Individuals With Methamphetamine Use Disorder After Long - Term Drug Rehabilitation . - pubmed
Discovery and validation of genomic regions associated with resistance to maize lethal necrosis in four biparental populations . - pubmed
The sudden outbreak of maize lethal necrosis ( MLN ) disease is seriously threatening the maize production in the region . - pubmed
BACKGROUND : Trypanosoma cruzi , the causal agent of Chagas disease , is monophyletic but genetically heterogeneous . - pubmed
Hepatocellular carcinoma ( HCC ) is a common human malignancy . - pubmed
The high rates of bone marrow involvement by these lymphomas pose a major therapeutic challenge due to the chemotherapy - resistant nature of the bone marrow microenvironment and the limited utility of rituximab - based salvage regimens in patients with relapsed / refractory disease . - pubmed
METHODS : The sample comprised 8 children of both sex , aged between 48 and 72 months with WS . - pubmed
We recruited patients with obstructing colorectal cancer from our registry . - pubmed
Background : Long non - coding RNAs nowadays emerge as important biomarkers or potential therapeutic targets discussed in human cancers . - pubmed
Therapies in Canine Atopic Dermatitis : An Update . - pubmed
Canine atopic dermatitis ( AD ) is one of the most common inflammatory skin diseases in dogs . - pubmed
This article provides a comprehensive review of the latest compounds for the treatment of canine AD . - pubmed
BACKGROUND : Glioblastoma multiforme ( GBM ) patients with a prior malignancy are usually excluded from clinical trials on GBM based on the assumption that this history will affect their survival outcomes . - pubmed
However , not much is known about the real impact of these prior malignancies on the survival of patients with subsequent GBM . - pubmed
PATIENTS AND METHODS : We used the Surveillance , Epidemiology , and End Results ( SEER ) Program to analyze data of GBM patients diagnosed between 1973 and 2014 . - pubmed
We calculated the overall and GBM - specific survival of these patients using the unadjusted Kaplan - Meier test and the multivariable covariate - adjusted Cox models . - pubmed
RESULTS : Of 51,158 GBM patients , 3,076 had a prior malignancy . - pubmed
The kinetoplastid parasite Trypanosoma brucei causes African trypanosomiasis in both humans and animals . - pubmed
METHODS : Additional to standard therapy , eight CRPS - patients with symptoms of less than 12 months were treated with topical 20 % ambroxol cream . - pubmed
RESULTS : Following treatment we found a reduction of spontaneous pain ( 6 patients ) , pain on movement ( 6 patients ) , edema ( seven patients ) , allodynia ( six patients ) , hyperalgesia ( seven patients ) , reduction of skin reddening ( four patients ) , improvement of motor dysfunction ( six patients ) and improvement of skin temperature ( four patients ) . - pubmed
Although standard protocols for undertaking acute and chronic toxicity tests of dissolved chemicals with D. - pubmed
Here we describe the acute and chronic toxicity methods with D. - pubmed
We present the unusual case of a 40 - year - old woman with multifocal GCTs affecting the intrahepatic biliary tree , which were initially suspected to be hepatic multiple metastases from a malignancy of unknown origin . - pubmed
Proteomics identification of radiation - induced changes of membrane proteins in the rat model of arteriovenous malformation in pursuit of targets for brain AVM molecular therapy . - pubmed
Methods : We employed in vivo biotinylation methodology that we developed , to label membrane proteins in the rat model of AVM post radiosurgery . - pubmed
DNA - DNA hybridization values between strain THG - SD5.5 T and C. - pubmed
These findings may explain the mechanism of increased vulnerability to infection and malignancy observed in older transplant patients . - pubmed
Endotoxin - resistant sheep proved nonresponsive to minor pulmonary embolism and to incompatible blood transfusion . - pubmed
After cerebral ischemia - reperfusion in rats , DCA was administered continuously for 21 days ; following which , histological analysis , and cognitive functional tests were conducted . - pubmed
Taken together , these findings suggested that long - term DCA administration improved cognitive function in a rat model of VD , and did so in part , by improving EPC function . - pubmed
Two ( 2.5 % ) patients had AR , and 3 ( 3.8 % ) had efficacy failure . - pubmed
The objective of this study was to determine whether regions of high - frequency Ripple activation ( HFRA ) observed on Ripple map provide useful ablation targets in patients with persistent AF . - pubmed
METHODS AND RESULTS : Consecutive patients underwent the first - time ablation of persistent AF ( n = 162 ) using a standard stepwise ( n = 105 ) or a Ripple map guided approach ( n = 57 ) . - pubmed
Acute termination of AF was observed in 91.2 % of the Ripple - guided patients vs 52.4 % in the stepwise approach , P & lt ; .0001 . - pubmed
Following a single ablation procedure , after 18 months 98.2 % of Ripple map guided patients were free of AF , compared with 81.4 % of standard stepwise ablation ( P = .005 ) . - pubmed
The rate of myocardial infarction was lower ( 1.1 % vs 2.4 % ) and ventilator use for > 48 hours was less frequent ( 0.4 % vs 2.6 % ) for LPMAC patients , though statistical significance was not reached . - pubmed
HCMV seropositivity is associated with specific proinflammatory immune phenotype in women with implantation failure . - pubmed
HCMV coevolved with humans for millions of years and is now one of the most widespread infections worldwide . - pubmed
Tube dysfunctions initiated 244 reinsertion / placement studies in 107 patients , 20 jejunostomy tube - related readmissions , and 78 phone calls to providers for tube dysfunction . - pubmed
We present a case of disseminated varicella infection in a newly diagnosed human immunodeficiency virus ( HIV ) patient causing acute pancreatitis at initial disease presentation and subsequently leading to multi organ dysfunction . - pubmed
The patient had no other risk factors for pancreatitis . - pubmed
Changes in Clozapine Bioavailability in a Percutaneous Endoscopic Gastrostomy - Fed Patient With Treatment - Resistant Schizophrenia . - pubmed
Methods : This is a prospective , open - label study ; patients with moderate to severe evaporative DE owing to MGD were consecutively enrolled and underwent two IPL treatment sessions at 3 - week intervals . - pubmed
Results : A total of 128 eyes of 64 patients ( 39 women , 25 men ; mean age 36.09 + - 11.13 years ) with moderate to severe DE owing to MGD consecutively received IPL treatment at days 1 and 21 . - pubmed
Conclusions : IPL treatment reduced the severity of DE symptoms and improved the overall tear film stability in patients with moderate to severe evaporative DE owing to MGD . - pubmed
In addition , visual complaints experienced by DE patients secondary to MGD significantly decreased . - pubmed
BACKGROUND : Liquid biopsy is a novel approach for cancer diagnosis , the value of which in human gastrointestinal ( GI ) cancer has been confirmed by the previous studies . - pubmed
This article summarized the recent advances in liquid biopsy with a focus on novel technologies and the use of it in the screening , monitoring , and treatment of human GI cancer . - pubmed
CONTENT : The concept of liquid biopsy was first used to define the detection of circulating tumor cells ( CTCs ) in cancer patients , and has been expanded to other biomarkers in blood and body fluids , such as circulating tumor DNA ( ctDNA ) , extracellular vesicles ( EVs ) and circulating tumor RNA . - pubmed
Material and methods : Data from 138 patients with rectal cancer ( I - III WHO ) , who were radically operated on in the period 2001 - 2004 in Bydgoszcz Oncology Centre were analysed . - pubmed
Results : Among all patients ( n = 138 ) and patients following sRT ( n = 84 ) 7.4% ... 5.9 % local recurrence and 24% ... 29 % distant metastases were observed in 5 - year follow - up . - pubmed
PURPOSE : The TWIST ( Testicular Work - up for Ischemia and Suspected Torsion ) score was developed to allow for expedited diagnosis of testicular torsion ( TT ) in children based on clinical variables : edema ( 2 points ) , hard mass ( 2 ) , absent cremasteric reflex ( 1 ) , high - riding testis ( 1 ) and nausea / vomiting ( 1 ) . - pubmed
Patients with previous scrotal pathology or trauma were excluded . - pubmed
RESULTS : Of 68 patients , 34 had TT ( 50 % ) . - pubmed
Fifteen patients had a score of 3 - 4 , among which seven had TT . - pubmed
Characterization and Exploration of Potential Neuroprotective Peptides in Walnut ( Juglans regia ) Protein Hydrolysate against Cholinergic System Damage and Oxidative Stress in Scopolamine - Induced Cognitive and Memory Impairment Mice and Zebrafish . - pubmed
The purpose of this study was to determine the neuroprotective effect and mechanism of walnut protein hydrolysates ( WPH ) against memory deficits induced by scopolamine in mice and further to validate the potent neuroprotective peptides identified by integrated approaches of in silico analysis and peptidomics in scopolamine - induced zebrafish . - pubmed
Rubber solvent was tested for its ability to induce chromosome aberrations and sister - chromatid exchanges in human whole blood cultures . - pubmed
A lipid - free preparation containing 0.076 % dexamethasone-21 - sodium - m - sulfobenzoate ( corresponding to 0.05 % dexamethasone ) has been applied to the right side of the back and the same vehicle without the agent to the left side of the back of 16 male subjects without any skin diseases . - pubmed
Experiments were carried out to assess the reduction rate of two salmonella strains ( S. - pubmed
The strain of S. - pubmed
Malignant salivary gland neoplasms in children are rare , most common being mucoepidermoid carcinoma , adenoid cystic carcinoma , acinic cell carcinoma and adenocarcinoma . - pubmed
Most germ - cell neoplasms of head and neck in children are teratomas . - pubmed
The authors report a case of endodermal sinus tumor ( EST ) of the parotid gland in a 2 - year - old girl , which recurred after chemotherapy . - pubmed
PATIENTS : Thirty infertility patients . - pubmed
U937 cells are established human monoblast cell line originally isolated from a patient with diffuse histiocytic lymphoma . - pubmed
Patients who had undergone bilateral neck dissection were injected on the tumor side . - pubmed
[ The prediction of the need for postoperative mechanical ventilation in patients with myasthenia gravis undergoing transsternal thymectomy ] . - pubmed
During a sixteen - year period , 51 patients with myasthenia gravis underwent trans - sternal thymectomy including extended resection of the adipose tissue around thymus . - pubmed
These service dogs were included in two different work strain groups ( patrol dogs and searching dogs ) . - pubmed
Other components of acid - base balance in blood do not show such variations ( patrol and searching dogs ) and these components justify that the adaptation of organism to the given strain gained suitable stabilisation . - pubmed
For studying the psychical and physical strain in service dogs it is recommended to include pH and pCO2 in the tests . - pubmed
During total hip replacement for 8 patients with hip joint osteoarthritis specimens of femoral articular cartilages of 3 types of involvement were taken , i.e. - pubmed
Effect of diltiazem on 2,4 - D - induced myotonia in rats . - pubmed
In rat diaphragm , exposed to 2.5 mM 2,4 - D in a tissue bath , myotonia was quantified by documenting the contraction time in response to direct stimulation with supramaximal electric stimuli . - pubmed
In vitro lipid - mobilizing activities of morphine ( MO ) and dynorphin-(1 - 10 ) amide ( DYA ) were compared using adipocytes of young adult rats ( body weight 170 - 200 g , age 50 - 60 days , diameter of adipocytes 54 + /- 1.12 microns ) and of 20 - month - old rats ( body weight 500 - 690 g , diameter of adipocytes 99.5 + /- 3.0 microns ) . - pubmed
Increased release of atrial natriuretic polypeptides in rats with DOCA - salt hypertension . - pubmed
Thus , it seems likely that the release of ANPs is increased in response to expansion of extracellular fluid volume or elevation of blood pressure , modifying the development of hypertension in DOCA - salt rats . - pubmed
Resistance of seizures to anti - epileptic therapy may be due to patient error , or to physician diagnostic and/or treatment error , rather than being truly intractable epilepsy . - pubmed
Repeated assessment of patients with refractory epilepsy is important , as causative or provocative factors may remain latent for long periods . - pubmed
Two - thirds of the patients with Friedreich ' s ataxia showed moderate cerebellar atrophy and an increase in the surface area of the fourth ventricle . - pubmed
Severe cerebellar atrophy and enlargement of the cerebellopontine angle cistern was seen in patients with olivopontocerebellar ( OPC ) atrophy and idiopathic cortical cerebellar atrophy . - pubmed
Diffuse proliferative glomerulonephritis was found in 60 % of patients with acute nephritic syndrome . - pubmed
Fifteen children with acute renal failure were biopsied , 2 of whom had haemorrhagic fever . - pubmed
To investigate the role of " behavioral inhibition to the unfamiliar " as an early temperamental characteristic of children at risk for adult panic disorder and agoraphobia ( PDAG ) , we compared children of parents with PDAG with those from psychiatric comparison groups . - pubmed
With a median follow - up of 16 months ( range , 6 - 35 ) , only 11 patients ( 37 % ) have had disease recurrence and eight ( 27 % ) have died . - pubmed
A luminol - enhanced chemiluminescence assay was used to measure light elaborated by peripheral blood polymorphonuclear leukocytes ( PMNs ) and by pulmonary alveolar macrophages ( PAMs ) from 14 healthy , normal subjects and 16 patients with sarcoidosis . - pubmed
Resting peripheral blood PMNs ( incubated only in medium ) from patients with sarcoidosis generated substantially more chemiluminescence than PMNs from normal control subjects ( p = 0.002 ) . - pubmed
With zymosan stimulation , greater chemiluminescence was produced by PMNs from untreated patients with sarcoidosis than from normal subjects ( p less than 0.05 ) , whereas no differences were noted with latex stimulation . - pubmed
Chemiluminescence for resting PAMs was not different between normal subjects and patients with sarcoidosis . - pubmed
Increased chemiluminescence by PMNs and PAMs from patients with sarcoidosis may reflect phagocyte activation in the disease process . - pubmed
Serratia marcescens infection : a growing threat . - pubmed
[ Correction of metabolic acidosis in patients with inflammatory diseases of the biliary tract ] . - pubmed
Removal of glomerular immune complex deposits by excess antigen in chronic mouse model of immune complex disease . - pubmed
3H - HpD was injected intravenously at a 10 mg / kg dose into 30 Sprague - Dawley rats ( Group A ) without tumors in order to clarify method . - pubmed
Separately , 3H - HpD of like dosage was injected into 20 Fischer-344 rats ( Group B ) , 5 control and 15 with a 9L gliosarcoma implanted in the left anterior cerebral cortex . - pubmed
The tumor area , peritumoral margin , and distant uninvolved areas of the Fischer-344 9L rats were likewise assayed . - pubmed
An assay was performed with 5 Fischer-344 9L brain tumor rats ( Group C ) , sacrificed at 24 hours . - pubmed
Preliminary clinic testings show that imuthiol restores T cell activities and regulates the ratio among T cell subsets in cancer patients , without untoward side effects . - pubmed
D - Galactosamine liver injury : absorption of endotoxin and protective effect of small bowel and colon resection in rabbits . - pubmed
D - Galactosamine is an amino sugar with unique hepatotoxic properties in animals . - pubmed
Although the mechanism of liver injury by galactosamine remains controversial , a role for bacterial endotoxin has been suggested . - pubmed
[ Effect of the pesticide carbaryl ( sevin ) on the course of experimental Erysipelothrix rhusiopathiae infection in rats ] . - pubmed
It was found that rats that were given carbaril for a long time in minimum amounts and were then subjected to infection developed a characteristic clinical picture and showed a high mortality rate ( nearly twice as high as that with the control animals ) . - pubmed
Aggressive pharmacotherapy for the treatment of patients with severe status asthmaticus includes theophylline and beta - adrenergic agonists such as isoproterenol . - pubmed
Penetration of cefoxitin into cerebrospinal fluid of infants and children with bacterial meningitis . - pubmed
Three consecutive doses of 75 mg of cefoxitin per kg were given intravenously every 6 h ( 225 mg / kg ) , in addition to penicillin or ampicillin , to 24 patients on days 4 and 5 and 9 and 10 of therapy for meningitis . - pubmed
Eighteen fetal lambs were divided into three experimental groups : diaphragmatic hernia ( DH ) , DH and simultaneous tracheal ligation ( DH / TL ) , and sham - operated controls ( C ) . - pubmed
Prolonged hypoxia in the adult rat causes a decline in endothelium - derived nitric oxide ( NO ) production in the pulmonary circulation . - pubmed
The pharmacokinetics of itraconazole oral solution were measured in seven patients receiving chemotherapy followed by autologous bone marrow transplantation for leukaemia or lymphoma . - pubmed
Thus serum concentrations of itraconazole suitable for antifungal prophylaxis can be attained in neutropenic patients , with the administration of an oral solution in a dosage of 5 mg / kg as either an od or bd schedule , following pre - autograft high - dose cytotoxic chemotherapy . - pubmed
A daily diet of meat including beef , chicken , and pork had a close relationship with cedar pollinosis . - pubmed
Comparative renal hemodynamic effects of lisinopril , verapamil , and amlodipine in patients with chronic renal failure . - pubmed
We investigated the effects of lisinopril , verapamil , and amlodipine in 26 hypertensive patients with chronic renal disease of varying etiologies . - pubmed
Patients who had a significant lowering of blood pressure in response to lisinopril and verapamil had favorable renal hemodynamic responses as well -- GFR remained stable , RBF was stable or increased , and filtration fraction , renal vascular resistance , and proteinuria tended to decrease . - pubmed
Our results demonstrate a heterogeneity in response to antihypertensive agents in patients with renal disease . - pubmed
A 15 - year - old boy with thalassaemia major treated with desferrioxamine , experienced fever associated with digestive disorders . - pubmed
Systemic yersiniosis was further confirmed by the finding of antibodies to Yersinia enterocolitica O5 . - pubmed
Evaluation of serum - associated embryotoxicity in women with reproductive disorders . - pubmed
RESULTS : After 72 hr , blastocyst spreading was significantly different depending on whether cultured in sera from women with unexplained infertility , anovulatory infertility , diethylstilbesterol exposure or controls . - pubmed
Neither sera from women with mechanical infertility ( 14 ) nor sera from women with endometriosis ( 8) affected blastocyst growth in culture . - pubmed
It can be inferred that the inhibitory effect of sera from women with certain types of infertility might be due to damage to the cytoskeleton . - pubmed
In an attempt to reestablish the dimorphic process in strains of Paracoccidioides brasiliensis in the transition phase ( Y reversible M ) and to reisolate them , five strains in the transitional phase due to the long time of preservation under mineral oil and two strains in the yeast - like phase were inoculated into male albino rats . - pubmed
The aim of this paper is to focus on our previous experience with the treatment of Group 3 and 4 neuroblastoma patients and on the therapeutic use of [ 131I ] MIBG , to better define the role of this radioactive drug in the treatment of neuroblastoma ( NB ) . - pubmed
[ 131I ] MIBG administered in advanced stage 4 patients induced a response in 50 % of the cases ( 2 complete response [ CR ] , 13 PR and 2 MR out of 34 children ) and 8 children treated for residual primary ( 4 cases ) or residual bone metastases ( 4 cases ) are long term survivors . - pubmed
We conclude that [ 131I ] MIBG is the treatment of choice in Group 3 patient with a residual primary tumor and could contribute to consolidate the response obtained in Group 4 patients . - pubmed
A study was therefore conducted on 40 women aged 20 - 35 , with iron - deficiency anaemia during or immediately after pregnancy all of whom presented Hb & lt ; 10 gr / dl , Ht & lt ; 33 % and serum iron & lt ; 60 micrograms / dl . - pubmed
All women with pregnancy - related pathological conditions , pre - existing on concomitant disease ( Type I diabetes , heart diseases etc . ) - pubmed
BACKGROUND : Assessment of language organization is crucial in patients considered for epilepsy surgery . - pubmed
We used fMRI , to assess language dominance in children with partial epilepsy . - pubmed
fMRI demonstrated left dominance in three additional children , and right dominance in one with early onset of left temporal epilepsy . - pubmed
Sixty patients with PSVT were randomized to have a bolus of 0.3 mg / Kg of diltiazem or 75 micrograms / Kg of verapamil . - pubmed
In relation with the drug safety , only 5 patients showed hypotension , without clinical relevance , in the diltiazem group . - pubmed
With verapamil one patient had a transitory ischemic attack after recover sinus rythm . - pubmed
3 ) Diltiazem was effective for slowing the ventricular rate in 83 % of the patients with AF who did not revert to sinus rythm . - pubmed
Noninvasive measurement of shortening in the fiber and cross - fiber directions in the normal human left ventricle and in idiopathic dilated cardiomyopathy . - pubmed
The purpose of this study was to estimate the extent of fiber and cross - fiber shortening in the normal human left ventricle and in patients with idiopathic dilated cardiomyopathy ( IDC ) . - pubmed
METHODS AND RESULTS : Ten normal subjects and nine patients with IDC were imaged with magnetic resonance tissue tagging . - pubmed
Anatomic fiber angles were not different between normal subjects and IDC patients . - pubmed
Epicardial fiber strain was -0.14+/-0.01 in normal subjects and -0.08+/-0.01 in IDC patients ( P<.0001 versus normal subjects ) . - pubmed
Endocardial fiber strain was -0.16+/-0.01 in normal subjects and -0.09+/-0.01 in IDC patients ( P<.0001 ) , and endocardial cross - fiber strain was -0.26+/-0.01 in normal subjects and -0.15+/-0.01 in IDC patients ( P<.0001 ) . - pubmed
Antibiotic - loaded hydroxyapatite blocks in the treatment of experimental osteomyelitis in rats . - pubmed
In this study , implantation of HABs loaded with the aminoglycoside antibiotic , arbekacin , were tested in established Staphylococcus aureus osteomyelitis in the proximal tibia of rats after debridement of the marrow cavity . - pubmed
Microvessel density was found to be associated with the overall survival in women with invasive carcinoma ( P & lt ; 0.01 ) . - pubmed
There was a significant correlation of microvessel density ( P & lt ; 0.05 ) with relapse - free survival in patients with regional lymph node metastasis . - pubmed
A Cox stepwise regression analysis revealed microvessel density , together with depth of invasion , regional lymph node status , and vascular invasion , to be a strong independent prognostic indicator for overall survival in patients with clinical stage IB cervical carcinoma . - pubmed
A venous occlusion ( VO ) test was performed preoperatively in 82 patients undergoing revascularization procedures . - pubmed
Patients recovered rapidly with minimal to no bruising , scarring , or pain . - pubmed
We quantified overall obesity by the body mass index ( BMI ) and used a previously validated magnetic resonance imaging ( MRI ) method to quantify abdominal fat in 63 healthy nondiabetic individuals aged 22 to 83 years . - pubmed
Autologous PBPCT in a patient with lymphoma and Sjogren ' s syndrome : complete remission of lymphoma without control of the autoimmune disease . - pubmed
A patient with primary Sjogren ' s syndrome developed massive gland enlargement and was diagnosed a MALT - type lymphoma stage IIA . - pubmed
After initial radiotherapy the patient relapsed with high grade immunoblastic lymphoma . - pubmed
However , subsequent to standard chemotherapy the patient experienced an exacerbation of arthralgia and vasculitis while his lymphoma remained in partial remission . - pubmed
Steroid treatment improved this , but the patient remained steroid - dependent and later died from therapy - resistant Pneumocystis carinii pneumonia while the lymphoma remained in complete remission . - pubmed
In this patient with systemic Sjogren ' s disease , PBPCT completely controlled the aggressive lymphoma but was not permanently effective for the autoimmune disease . - pubmed
Bone cyst causing acute lameness in a dog . - pubmed
Totally implanted venous access ports are excellent devices for delivering chemotherapeutic agents and prolonged intravenous infusions in patients with cancer . - pubmed
The antibacterial action of the oil extract obtained from tomato pulp has been studied with the use of museum strains Escherichia coli ATCC 25922 , Staphylococcus aureus ATCC 5638 - P and Candida albicans ATCC 885 - 653 , recommended for the determination of the antibacterial activity of medicinal preparations ( State Pharmacopoeia , edition XI ) , as well as Enterobacter , Streptococcus , Staphylococcus , Klebsiella and Escherichia clinical strains . - pubmed
Effectiveness of the analogue of natural Schisandrin C ( HpPro ) in treatment of liver diseases : an experience in Indonesian patients . - pubmed
OBJECTIVE : To determine the effect of dimethyl-4,4 '- dimethoxy-5,6 , 5 ' , 6 - dimethylene dioxybiphenyl-2,2 '- dicarboxylate ( HpPro ) on patients with acute and chronic liver diseases . - pubmed
CONCLUSION : Treatment with HpPro is effective to reduce liver impairment in acute and chronic liver diseases on Indonesian patients . - pubmed
We examined the mechanisms responsible for myocardial ischemia - reperfusion ( MI - R ) injury in a well - characterized animal model of type II diabetes mellitus . - pubmed
Diabetic ( db / db ) mice and their littermate nondiabetic controls were subjected to 30 min of left anterior descending coronary artery occlusion and 2 h of reperfusion . - pubmed
Diabetic and nondiabetic mice experienced similar - sized areas at risk per left ventricle : 50.4 + /- 2.0 and 53.4 + /- 4.1 % , respectively . - pubmed
However , myocardial necrosis ( percentage of area at risk ) was significantly greater ( P & lt ; 0.001 ) in diabetic than in nondiabetic animals : 56.3 + /- 2.8 and 27.2 + /- 3.1 % , respectively . - pubmed
The domestic cat is an outbred species with many identified analogues of human genetic diseases . - pubmed
In 1994 , the US Public Health Service published guidelines for the use of zidovudine to decrease the risk of perinatal transmission of human immunodeficiency virus ( HIV ) . - pubmed
Widespread incorporation of these guidelines into clinical practice has resulted in a dramatic decrease in the rate of perinatal HIV transmission and has contributed to more than a 75 % decrease in reported cases of pediatric acquired immunodeficiency syndrome ( AIDS ) since 1992 . - pubmed
Full implementation of recommendations for universal , routine prenatal HIV testing and evaluation of missed prevention opportunities will be critical to further decrease the incidence of pediatric HIV infection in the United States . - pubmed
In this strategy , the phenotype of the pancreatitis - affected pancreas is established by characterization of a large number of its transcripts using a high - density mouse cDNA microarray . - pubmed
Hypotensive effects of captopril on physical properties of the arterial system in young and adult rats . - pubmed
No age dependence of vascular response and reflex tachycardia to captopril has been found in rats between 4 and 12 months . - pubmed
CONCLUSIONS : Our results show observe the safety of glucocorticoid therapy among pregnant women with hypertensive disorders related to the possible raising of the blood pressure levels . - pubmed
CONCLUSIONS : Feasibility of using transgenic mice carrying photoactive reporter genes for studying cellular process of laser - inflicted wound repair in a noninvasive , in vivo manner was shown . - pubmed
METHODS : Two hundred forty - eight study subjects were allocated to two study groups and received either two doses of the combined hepatitis A and B vaccine ( 68 % of subjects ) or the corresponding monovalent hepatitis A and hepatitis B vaccines ( 32 % of subjects ) concomitantly in opposite arms . - pubmed
A double blind study was conducted to evaluate the effectiveness of the generation of magnetic fields on edema and on pain in patients submitted to surgery for bilateral hallux valgus . - pubmed
Also , for 18 months we compared 42 obese patients treated only with 1000 kcal / day diet ( group A ) with 31 obese patients subjected to BIB for 4 months + 1000 kcal / day diet ( group B ) . - pubmed
Weight loss was greater in male patients . - pubmed
CONCLUSION : The best indications for BIB were : morbidly obese opatients ( BMI & gt ; 40 ) and super - obese patients ( BMI & gt ; 50 ) in preparation for bariatric operations ; obese patients with BMI 35 - 40 with co - morbilities in preparation for bariatric surgery ; obese patients with BMI 30 - 35 with a chronic disease otherwise unresolved ; patients with BMI & lt ; 30 only in a multidisciplinary approach . - pubmed
Twenty multidrug - resistant vancomycin - resistant Enterococcus faecium strains of the VanA phenotype were isolated over a 1 year period from five patients in the intensive care unit at the University Hospital of Antalya , Turkey . - pubmed
OBJECTIVES : The Sensio study objectives were to assess the outcome of neuropsychiatric adverse reactions ( NPAR ) that develop after initiation of efavirenz ( EFV ) therapy , to ascertain the late NPAR after a 3 - month treatment period , to evaluate the impact of NPAR on patients ' quality of life ( QoL ) in a real - life population . - pubmed
METHODS : During a 6 - month period , consecutive HIV - infected adult outpatients receiving an ongoing EFV therapy for at least 3 months were asked to fill in a specifically designed self - administered questionnaire addressing sleep disturbances , behavioural changes , mood disturbances , anxiety , cognitive disorders , hallucinations , dizziness and the general impact on patients ' QoL. - pubmed
RESULTS : Among the 302 patients , 134 ( 44.37 % ) were below the age of 40 years ( juvenile - onset thrombosis ) , mean age being 35.3 years . - pubmed
PURPOSE : To identify the characteristics of adult patients who develop acute concomitant esotropia of adulthood . - pubmed
INTERVENTION : The charts of all adults with acute - onset concomitant esotropia who were examined at our institute between 1990 and 1997 were reviewed , and those who had developed the syndrome when they were older than the age of 16 years were included in this study . - pubmed
Nine of the 10 patients were myopic . - pubmed
CONCLUSIONS : In a well - defined group of adult patients with acute - onset concomitant esotropia , almost all were myopic , and all regained normal stereopsis after surgery . - pubmed
Propylene oxide ( PO ) is a high - volume chemical intermediate that causes a low incidence of nasal tumors in rodents exposed to high concentrations ( & gt ; or = 300 p.p.m . ) - pubmed
PURPOSE The purpose of the study was to determine the variables associated with postoperative pain and the clinical response of patients with uncomplicated hemorrhoidal disease treated with stapled rectal mucosectomy in the medium term . - pubmed
Effect of chemical protection and bone marrow treatment on radiation injury in mice . - pubmed
A new skeletal muscle relaxant , methocarbamol , was used in the treatment of 38 patients with a variety of severe neurological disorders and skeletal muscle spasm states . - pubmed
Mild side effects such as drowsiness were observed in five patients , mild weakness in three patients and excessive perspiration in one . - pubmed
In two of the five patients who complained of drowsiness , it disappeared upon reduction of dosage and did not reappear when original dosage was reinstituted . - pubmed
[ Effectiveness of combined balneoclimatic treatment of patients with psoriasis at Sochi - Matsesta health resort ] . - pubmed
Combination of femoral fracture treatment and corrective osteotomy in a child with osteogenesis imperfecta . - pubmed
We report a case of a 3 - year - old child with osteogenesis imperfecta type I who suffered an undisplaced femoral shaft fracture in the presence of a preexisting 32 degrees femoral antecurvation . - pubmed
Liver - directed adenoviral gene transfer in murine succinate semialdehyde dehydrogenase deficiency . - pubmed
In ulcerative colitis , steroids are rarely needed as 5 - aminosalicylates are effective in the majority of patients . - pubmed
In Crohn ' s disease , steroids are more often used ; however , in population - based studies , less than 50 % of patients have been treated with steroids , as there are alternative treatments available for the large group of patients with mild to moderate activity . - pubmed
OBJECTIVE : Despite similar disease patterns and treatment , there is great variation in clinical outcome between venous ulcer patients . - pubmed
METHODS : Consecutive patients assessed by a specialist nurse - led leg ulcer service between January 1998 and July 2003 with an ABPI>0.85 were included in this study . - pubmed
Patient age ( p & lt;0.001 , HR per year 0.989 , 95 % CI 0.984 - 0.995 ) and ulcer chronicity ( p = 0.019 , HR per month 0.996 , 95 % CI 0.993 - 0.999 ) were independent risk factors for delayed ulcer healing . - pubmed
CONCLUSIONS : Elderly patients with longstanding ulcers should be targeted for further research and may benefit from adjunctive treatments to improve clinical outcomes . - pubmed
Patients not treated with superficial venous surgery were at increased risk of leg ulcer recurrence . - pubmed
Regular exercise is important for patients with multiple sclerosis ( MS ) to maintain their functional ability and general health . - pubmed
PPT occurs in 50 % of women with high titre of these antibodies . - pubmed
Evaluation of the reticulocyte micronucleus assay in patients treated with radioiodine for thyroid cancer . - pubmed
In the present investigation , the utility and sensitivity of this method was studied in 44 young patients from Belarus , who were treated with 131I for thyroid cancer . - pubmed
We identified 8 children with genetically determined dyslipidemia : 2 children with homozygous and 6 with heterozygous familial hypercholesterolemia . - pubmed
Screening the progeny of young patients with CHD or familial hypercholesterolemia can identify children at excessive risk for future vascular disease . - pubmed
Adrenalectomy and castration in the genetically obese ( ob / ob ) mouse . - pubmed
The present studies have tested the hypothesis that adrenalectomy could modify the phenotypic expression of genetic obesity by examining the effects of adrenalectomy on the function of the gonadal system in lean and ob / ob mice . - pubmed
Adrenalectomy significantly slowed the weight gain of obese mice in comparison to sham - adrenalectomized controls . - pubmed
These data indicate that adrenalectomy has no effect on the physiologic control of the reproductive system in genetically obese mice , and are consistent with the hypothesis that the defect in the ob / ob mouse is a modulator of steroid action which over expresses glucocorticoid effects and under expresses gonadal steroid effects . - pubmed
During 2004 , 49 states and Puerto Rico reported 6,836 cases of rabies in nonhuman animals and 8 cases in human beings to the CDC , representing a 4.6 % decrease from the 7,170 cases in nonhuman animals and 3 cases in human beings reported in 2003 . - pubmed
Texas reported only 1 case of rabies in a dog that was infected with the dog / coyote rabies virus variant and only 22 cases associated with theTexas gray fox rabies virus variant ( compared with 61 cases in 2003 ) . - pubmed
Cases of rabies reported in cats , dogs , horses and mules , and sheep and goats decreased 12.5 % , 19.7 % , 31.8 % , and 16.7 % , respectively , whereas cases reported in cattle increased 174 % . - pubmed
Among the 8 cases of rabies in human beings , 1 person from Oklahoma and 3 from Texas died following receipt of infected organs and tissues from an Arkansas donor . - pubmed
METHODS : A decision - analytic model of the epidemiology and treatment of GHD in children was developed . - pubmed
In our 18 - year - old male patient , there were atrophic plaques unilaterally located on the trunk and arm , and white discoloration on all finger nails . - pubmed
Streptococcus pneumoniae is among the most common pathogens associated with chronic otitis media with effusion , which has been hypothesized to be a biofilm disease . - pubmed
Medication adherence in glaucoma : approaches for optimizing patient compliance . - pubmed
Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry . - pubmed
The aim of this study was to characterize endogenous nitroproteins , and those proteins that interact with nitroproteins , in a human pituitary nonfunctional adenoma so as to clarify the role of protein nitration in adenomas . - pubmed
A nitrotyrosine affinity column ( NTAC ) was used to preferentially enrich and isolate endogenous nitroproteins and nitroprotein - protein complexes from a tissue homogenate that was prepared from a human pituitary nonfunctional pituitary adenoma . - pubmed
Those data indicate that protein nitration might be an important molecular event in the formation of a human pituitary nonfunctional adenoma . - pubmed
Prevalence of aspirin resistance in patients with an evolving acute myocardial infarction . - pubmed
OBJECTIVE : To study the prevalence and importance of aspirin resistance in patients with an evolving acute myocardial infarction ( AMI ) by use of the Platelet Function Analyzer-100 . - pubmed
We hypothesized that the prevalence of aspirin resistance in patients with AMI was twice the prevalence in patients without AMI . - pubmed
METHODS : We included 298 consecutive patients with known cardiovascular disease who were admitted to hospital with symptoms suggestive of an AMI . - pubmed
The prevalence of aspirin resistance was significantly higher in patients with AMI as compared to patients without ( 36 % versus 20 % , OR 2.26 , CI 95 % 1.19 - 4.22 , p=0.0058 ) . - pubmed
CONCLUSIONS : Aspirin resistance is present in almost one fourth of patients admitted to hospital with symptoms suggestive of an AMI , and aspirin resistance is significantly associated with the diagnosis of a definite AMI . - pubmed
Coenzyme Q10 deficiency has been observed in patients with congestive heart failure , angina pectoris , coronary artery disease , cardiomyopathy , hypertension , mitral valve prolapse . - pubmed
Ubiquinone is the introduction of the metabolic drugs and may be recommended to patients with cardiovascular pathologies as an adjunct to conventional treatment . - pubmed
Assessment for additional spinal trauma in patients with cervical spine injury . - pubmed
This analysis includes 129 CSI patients ( 1.3 % of trauma admissions ) . - pubmed
Cervical spine radiographs diagnosed injuries in 71 per cent of CSI patients . - pubmed
Injuries involved two adjoining vertebrae in 38 patients and three or more adjoining vertebrae in 7 patients . - pubmed
Injuries were isolated in 45 per cent and were multilevel in the remaining CSI patients . - pubmed
Assessment of the entire spinal column should be done in patients with CSI . - pubmed
BACKGROUND : Anisakis simplex is a fish parasite that can cause allergy in humans . - pubmed
Omeprazole before endoscopy in patients with gastrointestinal bleeding . - pubmed
METHODS : Consecutive patients admitted with upper gastrointestinal bleeding underwent stabilization and were then randomly assigned to receive either omeprazole or placebo ( each as an 80 - mg intravenous bolus followed by an 8 - mg infusion per hour ) before endoscopy the next morning . - pubmed
There were no significant differences between the omeprazole group and the placebo group in the mean amount of blood transfused ( 1.54 and 1.88 units , respectively ; P=0.12 ) or the number of patients who had recurrent bleeding ( 11 and 8 , P=0.49 ) , who underwent emergency surgery ( 3 and 4 , P=1.00 ) , or who died within 30 days ( 8 and 7 , P=0.78 ) . - pubmed
On endoscopy , fewer patients in the omeprazole group had actively bleeding ulcers ( 12 of 187 , vs. 28 of 190 in the placebo group ; P=0.01 ) and more omeprazole - treated patients had ulcers with clean bases ( 120 vs. 90 , P=0.001 ) . - pubmed
The effect of dietary high - amylose corn starch ( HACS ) of varying dietary fiber ( DF ) content on plasma cholesterol was examined in ovariectomized ( OVX ) rats . - pubmed
PARTICIPANTS : One hundred consecutive patients with cough , ages 1 to 90 . - pubmed
STUDY DESIGN : Patients who underwent partial hepatectomy between 1997 and 2001 , with complete preoperative radiographic imaging and postoperative pathologic assessment of steatosis , were retrospectively analyzed . - pubmed
Furthermore , specific technologies are now available to screen animal model or human blood samples for novel , improved markers of chronic disease states , such as atherosclerosis or for earlier indicators of acute myocardial stress , including ischemia / reperfusion injury and heart failure . - pubmed
Among special subgroup of patients , in which acute pain exacerbation , mechanical block or early OA , utilizing arthroscopic techniques revealed satisfactory results . - pubmed
METHODS : Male Wistar rats were randomly divided into three groups : control group ; fibrosis group , which received the solution of CCl4 in oil twice a week for 5 weeks ; and hepatectomy group , which underwent 70 % hepatectomy . - pubmed
[ Surgical treatment of 154 patients with non - traumatic acute lower limb ischemia ] . - pubmed
METHODS : The clinical data of 154 acute lower limb ischemia patients surgically treated from July 1999 to December 2007 were retrospectively analyzed . - pubmed
The patients were divided into two groups according to pathogenesis : acute arterial embolism group ( 99 cases ) and acute arterial thrombosis group ( 55 cases ) . - pubmed
RESULTS : Female experienced acute arterial embolism more often than man ( 60.6 % vs 39.4 % , P & lt ; 0.05 ) , and more acute arterial thrombosis occurred in man ( 72.7 % vs 27.3 % , P & lt ; 0.05 ) . - pubmed
PATIENTS AND METHODS : In the first part , sera from 24 SSc patients ( 12 with pulmonary arterial hypertension ( PAH ) and 12 without ) and 36 idiopathic PAH patients , tested in pooled sera for groups of three , were compared with a sera pool from 14 healthy controls ( HC ) . - pubmed
An unusual case of hospital - acquired infection : Legionella Longbeachae . - pubmed
METHOD : Between 1992 and 2000 a consecutive series of 80 patients with a high transsphincteric fistula of cryptoglandular origin underwent TAFR . - pubmed
The medical records revealed that only one of these patients presented with a recurrent fistula after 28 months . - pubmed
The other 53 patients were sent a questionnaire in 2006 aimed to determine whether they had any complaints or signs of a recurrent fistula . - pubmed
None of these patients reported any complaints or signs of a recurrent fistula . - pubmed
CONCLUSION : At a median time interval of 3.6 months fistula healing was observed in 54 patients ( 68 % ) . - pubmed
Only one patient ( 2 % ) encountered a recurrence . - pubmed
Pharmacomechanical thrombectomy for iliofemoral deep vein thrombosis : an alternative in patients with contraindications to thrombolysis . - pubmed
OBJECTIVE : Venous lysis is usually reserved for symptomatic patients with acute deep vein thrombosis ( DVT ) and low risk for bleeding . - pubmed
METHODS : A retrospective review of all patients with symptomatic DVT treated between 2007 and 2008 with PMT was performed . - pubmed
There were no major systemic bleeding complications , but access site hematoma occurred in two patients and worsening of pre - existing rectus sheath hematoma requiring transfusion occurred in another two . - pubmed
Limb salvage was maintained in 100 % of patients who presented with phlegmasia . - pubmed
CONCLUSIONS : PMT can be safely and effectively used for subacute iliocaval and iliofemoral DVT and in patients with contraindications for lytic therapy , resulting in improved functional outcomes relative to their debilitated state before the procedure . - pubmed
Influence of operative timing on prognosis of patients with acute subdural hematoma . - pubmed
OBJECTIVE : To study the influence of operative timing on the prognosis of patients with acute subdural hematoma ( ASDH ) in order to provide theoretical basis for clinical treatment . - pubmed
METHODS : The clinical data of 202 patients with ASDH undergoing operations were collected , and the mortalities and functional survival rates were analyzed 2 , 4 , 6 , and 8 hours after injury . - pubmed
CONCLUSIONS : Operative timing has potential influences on the prognosis of patients with ASDH . - pubmed
Their intravenous injection into mice causes marked hemoglobinuria , anemia , and death . - pubmed
There is evidence that this anemia is not the only cause of death of these animals . - pubmed
The sporadic reports on vaccine - induced inflammatory myopathies include cases of hepatitis B virus , bacillus Calmette - Guerin , tetanus , influenza , smallpox , polio , diphtheria , diphtheria - pertussis - tetanus , combination of diphtheria with scarlet fever and diphtheria - pertussis - tetanus with polio vaccines . - pubmed
The objective of this study was to investigate the sleep architecture and the presence of depression in individuals with low endogenous melatonin levels . - pubmed
We propose that the combination of FUNC and FOUR scores will be a better prognostic indicator than either FUNC or FOUR score alone for S - ICH patients . - pubmed
METHODS : We conducted a retrospective chart review of all S - ICH patients ( & gt;18 years of age ) from January 2008 to May 2010 . - pubmed
CONCLUSIONS : The combination of the FUNC and the FOUR scoring system is a better prognostication indicator for S - ICH patients than either FUNC or FOUR score . - pubmed
BACKGROUND : The purpose of this study was to determine the effect of lymph node sampling and taking of blind biopsies as part of the surgical staging procedure for early ovarian cancer on disease - free survival ( DFS ) and overall survival ( OS ) in patients who received no adjuvant chemotherapy . - pubmed
METHODS : In the EORTC ACTION Trial , 448 patients with early ovarian carcinoma were randomized between November 1990 and March 2000 - 224 patients to observation and 224 to adjuvant platin - based chemotherapy . - pubmed
Recurrences occurred in 11 ( 14.6 % ) of 75 patients in group A , 16 ( 34.8 % ) of 46 patients in group B , and 5 ( 35.7 % ) of 14 in group C. The 5 - year DFS in group A was 79 % versus 61 % and 64 % in groups B and C , respectively . - pubmed
The objective of this pictorial essay is to highlight the key role of computed tomography scanning ( CT scan ) , particularly minimum intensity projection ( MinIP ) reformation , with regards to the diagnosis of hypersensitivity pneumonitis ( HP ) and its contribution to patients ' management . - pubmed
Correlations in brain atrophy changes between rabbit brain and human AD brain were found for frontal lobe and hippocampal regions . - pubmed
In contrast , other regions such as midbrain , temporal lobe , and lateral ventricles were not correlated with rabbit brain atrophy changes in the corresponding regions . - pubmed
Among the loci targeted by pathogen - driven selection , we found an enrichment of genes associated to autoimmune diseases , such as celiac disease , type 1 diabetes , and multiples sclerosis , which lends credence to the hypothesis that some susceptibility alleles for autoimmune diseases may be maintained in human population due to past selective processes . - pubmed
Here , we used ' HLA - humanized ' mice to discern the potential relative contribution of DRB1 * 1501 and DQB1 * 0602 alleles to susceptibility to " humanized " MS - like disease induced by PLP , one of the most prominent and encephalitogenic target - antigens implicated in human MS . - pubmed
RESULTS : The group comprised 51 patients with HAP . - pubmed
The most frequent bacterial pathogens were strains of Klebsiella pneumoniae , Pseudomonas aeruginosa , Burkholderia cepacia complex and Escherichia coli , together accounting for 72 % . - pubmed
Eighteen patients died directly due to HAP , an overall mortality rate of 35 % . - pubmed
However , it does document the clinical impact of bacterial resistance on the survival or death of patients with HAP . - pubmed
Do cervical cancer data justify HPV vaccination in India ? - pubmed
Although HPV prevalence is higher in cancer patients ( 93.3 % ) than healthy patients ( 7.0 % ) and HPV types 16 and 18 are most prevalent in cancer patients , population prevelance data are poor and studies highly variable in their findings . - pubmed
In particular , mitochondrial dysfunction has long been implicated in the etiopathogenesis of Parkinson ' s disease ( PD ) , based on the observation that mitochondrial toxins can cause parkinsonism in humans and animal models . - pubmed
Retrograde aortic dissection at the proximal part of the aortic endovascular graft and a guidewire - induced iatrogenic left ventricular pseudoaneurysm were presented in this patient after the stent - grafting procedure . - pubmed
BACKGROUND : Prognosis of localised gastrointestinal stromal tumour ( GIST ) is heterogeneous , notably for patients with AFIP intermediate or high risk of relapse , who are candidates to adjuvant imatinib . - pubmed
We also analysed a data set from 28 patients with advanced GIST treated with neo - adjuvant imatinib . - pubmed
BACKGROUND : Several experimental studies in stroke patients suggest that mirror therapy and various virtual reality programs facilitate motor rehabilitation . - pubmed
Moreover , we attempted to delineate the role of visual modulation within the virtual environment that affected corticospinal excitability in healthy subjects and stroke patients . - pubmed
METHODS : A total of 18 healthy subjects and 18 hemiplegic patients were enrolled into the study . - pubmed
In healthy subjects and stroke patients , the virtual mirror task with intermittent visual feedback significantly facilitated corticospinal excitability of MEPs compared with continuous visual feedback . - pubmed
This provides neurophysiological evidence supporting the application of the virtual mirror paradigm using various visual modulation technologies to upper extremity rehabilitation in stroke patients . - pubmed
UNLABELLED : The goal of this initial investigation was to examine the potential benefit of a frequency modulation ( FM ) system for 11 children diagnosed with autism spectrum disorders ( ASD ) , attention - deficit hyperactivity disorder ( ADHD ) , or both disorders through measures of speech recognition performance in noise , observed classroom behavior , and teacher - rated educational risk and listening behaviors . - pubmed
The sequence similarities of this strain to the members of the family Microbacteriaceae were less than 97 % , with the highest values observed with Cryobacterium mesophilum MSL-15(T ) ( 96.3 % ) , Cryobacterium roopkundense RuGl7(T ) ( 96.2 % ) , Labedella gwakjiensis KSW2 - 17(T ) ( 96.2 % ) , Cryobacterium luteum Hh15(T ) ( 96.2 % ) , Cryobacterium psychrophilum DSM 4854(T ) ( 96.2 % ) , Klugiella xanthotipulae 44C3(T ) ( 96.0 % ) and Amnibacterium kyonggiense KSL51201 - 037 ( T ) ( 96.0 % ) . - pubmed
The type strain of Naasia aerilata is 5116S-4(T ) ( = KACC 15517(T ) = NBRC 108725(T ) ) . - pubmed
B - cell subsets in patients with transient hypogammaglobulinemia of infancy , partial IgA deficiency , and selective IgM deficiency . - pubmed
OBJECTIVE : In the present study , we used flow cytometry to analyze peripheral blood B - cell subsets in patients with THI and unclassified hypogammaglobulinemia ( UCH ) , partial IgA deficiency , and selective IgM deficiency . - pubmed
METHODS : The study population comprised 41 patients with hypogammaglobulinemia ( THI , 18 ; UCH , 23 ) , 16 patients with partial IgA deficiency , and 16 patients with selective IgM deficiency who were admitted to Ankara University Department of Pediatric Immunology - Allergy between January 2010 and April 2011 , as well as 29 healthy controls . - pubmed
Naive B - cell percentages were significantly higher and activated B - cell values lower in the THI patients than in the UCH patients and age - matched healthy controls . - pubmed
Furthermore , we observed that naive B cell values were higher in patients with THI . - pubmed
METHODS : A deformable image registration tool was used to plan and accumulate dose over all phases of the breathing cycle for conventional and robust - inspired IMRT strategies of eight nonsmall cell lung cancer patients exhibiting peak - to - peak respiratory motion with amplitudes ranging from 1 to 2 cm in the craniocaudal direction . - pubmed
In the present study , we report the clinical data in the case of a 46 - year - old female patient , treated due to 5 - day forehead swelling accompanied by dizziness . - pubmed
The current study addresses this gap by investigating neural responses to a mild visual stress challenge with real - time assessment of adrenal hormones in women with MDD in remission and controls . - pubmed
Fifteen women with recurrent MDD in remission ( rMDD ) and 15 healthy control women were scanned on a 3 T Siemens MR scanner while viewing neutral and negative ( stress - evoking ) stimuli . - pubmed
Compared to controls , rMDD women demonstrated higher anxiety ratings , increased cortisol levels , and hyperactivation in the amygdala and hippocampus , p<0.05 , family - wise error ( FWE)-corrected in response to the stress challenge . - pubmed
INTRODUCTION : Scaling up routine HIV testing represents a key component of the National HIV / AIDS Strategy . - pubmed
Campylobacter jejuni is an important cause of human foodborne gastroenteritis ; strategies to prevent infection are hampered by a poor understanding of the complex interactions between host and pathogen . - pubmed
The clinical data of 7 newly diagnosed patients with primary tonsil DLBCL from October 2009 to February 2013 were analyzed retrospectively . - pubmed
It is concluded that most patients with primary tonsil DLBCL are at early stage , have an obvious characteristics of onset ages , clinical manifestations , pathological histology and achieve better remission through combined chemotherapy and radiotherapy . - pubmed
METHODS : In this prospective sham - controlled trial , infants ( 0 - 6 months ) with symptoms suggestive of gastroesophageal reflux disease were studied using 8 - hour pH - impedance , cardiorespiratory and video monitoring , direct nurse observation , and a validated questionnaire . - pubmed
METHODS : The expression of miR-224 in the cancer tissues and their adjacent tissues in 120 gastric cancer patients were detected by real - time quantitative PCR . - pubmed
The biological effects of miR-224 ASO on human gastric cancer SGC7901 cells was assessed by MTT assay , clone formation assay , flow cytometry and in vivo experiment in nude mice . - pubmed
RESULTS : Compared with the control group ( 0.50 + - 0.07 ) , miR-224 ASO significantly reduced the miR-224 mRNA expression in the cancer patients ( 0.09 + - 0.01 , P & lt ; 0.05 ) . - pubmed
CONCLUSIONS : MiR-224 is overexpressed in human gastric cancer . - pubmed
Improvement of verbal fluency in patients with diffuse brain injury over time . - pubmed
BACKGROUND : Diffuse axonal injury ( DAI ) , a common cause of neurological sequelae in patients with traumatic brain injury ( TBI ) , is considered one of the most prevalent forms of primary neuronal injury in patients with severe TBI . - pubmed
The aim of the present study was to compare verbal fluency ( VF ) performance at 6 and 12 months after the trauma in a same group of patients with DAI . - pubmed
METHODS : Eighteen patients with moderate to severe DAI and 17 healthy volunteers were enrolled . - pubmed
Sixty randomly selected DM1 patients ( 14.5 + - 3.2 years ) and 30 healthy ( 13.5 + - 2.8 years ) volunteers were enrolled in the study . - pubmed
Our results indicate that three monocyte subsets are distinguishable in the groups of young diabetic patients and the healthy , similarly to in the blood of adults . - pubmed
DM1 patients were characterized by higher values of apoptotic monocytes than the healthy . - pubmed
They may be useful for controlling excessive monocyte apoptosis in diabetic patients . - pubmed
Power Doppler ultrasonographic assessment of the ankle in patients with inflammatory rheumatic diseases . - pubmed
The aim of this paper is to illustrate the US assessment of ankle lesions in patients with inflammatory rheumatic diseases , including rheumatoid arthritis , spondyloarthritis , and systemic lupus erythematosus , focusing on the utility of PDUS . - pubmed
OBJECTIVES : To evaluate the usefulness of the information obtained with SPECT , coronary angio - CT and fusion images , in patients with stable ischemic disease who need invasive coronary angiography ( IA ) . - pubmed
MATERIAL AND METHODS : Forty - six patients ( 65.98 + -8.3 years ) with coronary disease were prospectively included . - pubmed
The fusion images generated after undergoing IA were used to evaluate the performance of these techniques in the diagnosis of multi - vessel coronary disease , the detection of the culprit vessel and the therapeutic management of these patients . - pubmed
However , the performance of fusion images in patients with stable ischemic disease , who have undergone a SPECT as the first non - invasive study and need IA , does not seem indicated because they would not have changed the therapeutic management derived from SPECT and IA information . - pubmed
Endovascular treatment of abdominal aortic aneurysm in a 26 - year - old man . - pubmed
We present endovascular treatment of abdominal aortic aneurysm in a 26 - year - old man with a 10 - year follow - up . - pubmed
A young patient presenting with an abdominal aortic aneurysm is extremely rare , and data describing this population are limited . - pubmed
CONCLUSIONS : Enrichment of diet with onion as functional ingredient could be proposed as a complementary approach to prevent or partially modulate vascular dysfunction , reducing some of the risk indexes linked to initial development of atherosclerosis . - pubmed
Brainstem evoked potential in newly diagnosed patients of subclinical hypothyroidism . - pubmed
AIMS : The aim is to assess the auditory pathway by brainstem auditory evoked potentials ( BAEPs ) in newly diagnosed patients of subclinical hypothyroidism and healthy sex- and age - matched controls . - pubmed
CONCLUSION : The prolongation of wave V in BAEPs of both ears suggests that the central auditory pathway is affected significantly in subclinical hypothyroid patients . - pubmed
PARTICIPANTS : A total of 120 TS patients , aged 0 to 48 years . - pubmed
Kudo in rats with spared nerve injury . - pubmed
rotata ) is a medical plant that has been traditionally used for centuries for the treatment of pain , such as bone and muscle pain , joint pain and dysmenorrhea . - pubmed
Randomized trials ( RCT ) show no meaningful improvement in hypertension control with renal artery stenting ( RAS ) compared to medical therapy alone in patients with largely moderate hypertension and intermediate grade stenoses . - pubmed
Observational studies of patients with severe hypertension and high - grade stenoses on multiple medications report blood pressure improvement after RAS . - pubmed
We aimed to study lipid profile 1 year after bariatric surgery and compare its changes between the different procedures in patients matched for initial weight and weight loss . - pubmed
Patients were matched for age ( + -5 years ) , sex , pre - surgery body mass index ( BMI ) ( + -2 Kg / m(2 ) ) and excess weight loss ( EWL ) ( + -5 % ) . - pubmed
Autosomal recessive non - syndromic hearing loss ( ARNSHL ) is one of the most common genetic diseases in human and is subject to important genetic heterogeneity , rendering molecular diagnosis difficult . - pubmed
Motor Skills in Hearing Impaired Children with or without Cochlear Implant -- A Systematic Review . - pubmed
A certain percentage of the patients with chronic subtalar instability is incorrectly labeled with the diagnosis of a sinus tarsi syndrome . - pubmed
The anticancer activities of pristimerin have been illustrated in various cancer cell lines and animal models . - pubmed
MATERIAL AND METHODS : A total of 195 patients with BRONJ in the mandible were included in this prospective study . - pubmed
RESULTS : Recurrence of BRONJ was significantly reduced ( p = 0.023 ) as was extent of necrosis ( p = 0.001 ) in patients with mylohyoid flaps . - pubmed
PURPOSE : To investigate the effectiveness and application of transcatheter arterial embolization ( TAE ) plus systemic vincristine for treatment of corticosteroid - resistant vascular tumors associated with Kasabach - Merritt phenomenon in infants . - pubmed
MATERIALS AND METHODS : TAE was performed in 17 infants ( average age , 4.3 mo + - 2.4 ; range , 1 - 10 mo ) with corticosteroid - resistant vascular tumors associated with Kasabach - Merritt phenomenon , followed by intravenous vincristine once weekly for systemic chemotherapy . - pubmed
Age - related presence of selected viral and bacterial pathogens in paraffin - embedded lung samples of dogs with pneumonia . - pubmed
In archived formalin - fixed and paraffin wax - embedded lung samples from 68 cases with the clinical and histologic diagnosis of pneumonia the histological pattern of pneumonia was re - evaluated and the samples were further investigated for the following infectious agents : canine distemper virus ( CDV ) , canine adenovirus type 2 ( CAV-2 ) , canine respiratory coronavirus ( CRCoV ) , Bordetella ( B. ) - pubmed
The correct detection of CDV had been achieved in ten out of eleven positive cases ( 90.9 % ) upon initial investigation , but the presence of bacterial pathogens , like B. - pubmed
While CDV and CRCoV infections were exclusively found in dogs younger than one year , the vast majority of infections with P. - pubmed
We hypothesized that OA to articles in human health or environmental journals was greater than access to animal health literature . - pubmed
The proportion of OA journals in animal health ( 40 % ) differed significantly from journals categorized as human ( 28 % ) , environment ( 28 % ) , and more than 1 category ( 29 % ) . - pubmed
CONCLUSIONS : OA to human health literature is more comparable to animal health than hypothesized . - pubmed
LPS is a bacterial cell wall component that is capable of inducing osteoclast formation and pathological bone resorption . - pubmed
Potential clinical impact of the film array meningitis encephalitis panel in children with suspected central nervous system infections . - pubmed
The FilmArray Meningitis Encephalitis Panel , a multiplex PCR for testing of cerebrospinal fluid , was compared to conventional diagnostic methods in children with suspected central nervous system infections . - pubmed
We report a patient with long history of sarcoidosis and Crohns disease with newly developed lymphadenopathy which was found to be due to Castleman ' s disease . - pubmed
STEMI Secondary to Coronary Vasospasm : Possible Adverse Event of Methylphenidate in a 21 - Year - Old Man with ADHD . - pubmed
We present the case of a 21 - year - old man diagnosed with ADHD who recently started therapy with Ritalin Adult 20 mg for at least 3 days . - pubmed
In 2014 , out of 1140 influenza samples received at the National Influenza Centre , 888 samples ( 78 % ) were A ( H3N2 ) strains , 244 ( 21.3 % ) were type B strains , and 8 ( 0.7 % ) were A ( H1N1 ) pdm09 strains . - pubmed
Hyperuricemia in Children and Adolescents with Autism Spectrum Disorder Treated with Risperidone : The Risk Factors for Metabolic Adverse Effects . - pubmed
Risperidone , one of the atypical antipsychotics , might be related to the hyperuricemia among autism spectrum disorder ( ASD ) patients . - pubmed
The aims of this study were to determine the prevalence of hyperuricemia in ASD patients treated with risperidone and to determine associations between serum uric acid levels and risperidone dosage , treatment duration , and metabolic parameters . - pubmed
Methods : 127 children and adolescents with ASD treated with risperidone and 76 age - matched risperidone - naive patients with ASD were recruited . - pubmed
Results : Hyperuricemia was present in 44.70 % of risperidone - naive patients with ASD and 57.50 % of ASD patients treated with risperidone . - pubmed
Conclusion : Hyperuricemia may play a role in metabolic adverse effect in children and adolescents with ASDs receiving the high dose and/or the long - term treatment with risperidone . - pubmed
METHODS : Patients with PMS formed the PMS group and age - matched healthy normal controls were included in the control group . - pubmed
Patients with PMS were divided into two subgroups according to coexistence of FMS or not . - pubmed
The mean physical component summary of SF-36 was low in the PMS patient with FMS . - pubmed
However , an acute systemic gas and fat embolic syndrome similar to DCS in human divers was described in beaked whales that stranded in temporal and spatial association with military exercises involving high - powered sonar . - pubmed
Two Risso ' s dolphin ( Grampus griseus ) out of 493 necropsied cetaceans stranded in the Canary Islands in a 16 - year period ( 2000 - 2015 ) , had a severe acute decompression sickness supported by pathological findings and gas analysis . - pubmed
BACKGROUND : Chronic low - grade inflammation is believed to contribute , at least in a subset of patients , to the development of bipolar disorder ( BD ) . - pubmed
BACKGROUND : The repair of extensive upper limb skin lesions in pediatric patients is extremely challenging due to substantial limitations of flap size and donor - site morbidity . - pubmed
METHOD : Between March 2013 and August 2016 , 11 patients underwent reconstructive treatment for extensive skin lesions in the upper extremity using a preexpanded intercostal artery perforator flap . - pubmed
We aim to report cases of melanoma patients treated with diphencyprone in a single Brazilian institution and highlight their outcomes . - pubmed
Since 2012 , we have treated 16 melanoma patients with cutaneous metastases with topical diphencyprone . - pubmed
We believe topical diphencyprone is a feasible treatment that can be another option for treating melanoma patients , especially in cases of in - transit or extensive disease . - pubmed
Utility of serum Aspergillus - galactomannan antigen to evaluate the risk of severe acute exacerbation in chronic obstructive pulmonary disease . - pubmed
OBJECTIVES : To explore whether serum levels of Aspergillus - galactomannan antigen could be used to evaluate the risk of severe acute exacerbation of COPD ( AE - COPD ) . - pubmed
METHODS : We measured the Aspergillus - galactomannan antigen levels of 191 patients with stable COPD , and examined its clinical relevance including AE - COPD . - pubmed
High Aspergillus - galactomannan antigen level ( & gt;=0.7 ) was associated with older age and presence of bronchiectasis and cysts on computed tomography images . - pubmed
Compared to patients with low Aspergillus - galactomannan antigen level ( & lt;0.7 ) , patients with high Aspergillus - galactomannan antigen level had significantly higher incidence of severe AE - COPD ( P = 0.0039 , Gray 's test ) and respiratory - related mortality ( P = 0.0176 , log - rank test ) . - pubmed
METHODS : The study included 77 patients ( 63 men and 14 women ; median age , 78 years ) who underwent elective TEVAR for aortic arch disease between 2009 and 2013 . - pubmed
RESULTS : Perioperative ischemic stroke occurred in nine patients , and no patient died within 30 days postoperatively . - pubmed
Univariate analyses demonstrated that the shagginess score was significantly higher in patients who developed postoperative cerebral infarction than in those who did not ( P = .04 ) . - pubmed
The aim of this study was to assess plasma levels of monoamine neurotransmitters ( catecholamines , indolamines , and intermediate metabolites ) in patients with FM and healthy controls to investigate possible alterations in the metabolism of these molecules in FM . - pubmed
METHOD : We measured plasma catecholamines ( epinephrine , norepinephrine , and dopamine ) , as well as indolamines and intermediary metabolites ( serotonin or 5 - hydroxytryptamine [ 5 - HT ] , 5 - hydroxyindolacetic acid [ 5 - HIAA ] , 5 - hydroxytryptophan [ 5 - HTP ] , and N - acetyl-5 - hydroxytryptamine [ Nac-5 - HT ] ) in 35 women with FM and 12 age - matched healthy women . - pubmed
RESULTS : Higher levels of norepinephrine and lower levels of dopamine , 5 - HT , 5 - HIAA , and 5 - HTP were found in women with FM in comparison with controls . - pubmed
CONCLUSIONS : These findings show evidence of the dysregulation of the catecholamine and indolamine pathway in patients with FM , which may contribute to the physiopathology of this syndrome . - pubmed
This article studies the epidemiological and economic impacts of a universal testing and treatment policy of Human Immunodeficiency Virus ( HIV ) in South Africa . - pubmed
A total of 72 young people ( 15 to 25 years old ) with suicidal ideation / self - injuring behaviour and BPD traits and symptoms will participate in the study . - pubmed
Among the 1286 patients with AIS who underwent spinal fusion , the mean LOS was 4.90 days [ 95 % confidence interval ( CI)=4.84 - 4.97 ; SD=1.19 ] . - pubmed
Plasmodium falciparum malaria prevalence was positively associated with living in the lake - endemic area ( adjusted odds ratio [ aOR ] 3.46 ; 95 % confidence interval [ 95 % CI ] 1.63 , 7.37 ) , paternal occupation as peasant farmer ( aOR 1.87 ; 1.08 , 3.26 ) or manual laborer ( aOR 1.83 ; 1.00 , 3.37 ) , and keeping dogs ( aOR 1.62 ; 0.98 - 2.69 ) or cows ( aOR 1.52 ; 0.96 - 2.40 ) inside or near the household . - pubmed
Plasmodium falciparum malaria prevalence was inversely associated with indoor residual insecticide spraying ( IRS ) ( aOR 0.44 ; 0.19 , 1.01 ) , having a household connected to electricity ( aOR 0.47 ; 0.22 , 0.98 ) , and a household with two ( aOR 0.45 ; 0.22 , 0.93 ) or & gt;= three rooms ( aOR 0.41 ; 0.18 , 0.93 ) . - pubmed
Tissue Concentrations of Zinc , Iron , Copper , and Magnesium During the Phases of Full Thickness Wound Healing in a Rodent Model . - pubmed
This study analyzed the kinetics of zinc , iron , copper and magnesium concentrations in a full thickness open wound rat model over 14 days . - pubmed
We made wounds with a diameter of 6 mm on the back of Lewis rats and let them heal naturally prior to analysis by histology and inductively coupled plasma mass spectrometry analysis . - pubmed
For the assessment of goiter , HVI for students aged 8 and 10 years and BMIV for students aged 9 years might serve as better indicators . - pubmed
MATERIAL AND METHODS : Twenty - seven teenagers with TS , aged from 12 to 15 years , and their mothers were included in the main group . - pubmed
In addition , mothers of children with TS were characterized by a high level of alexithymia and a significantly lower integrative level of emotional intelligence compared to the control group . - pubmed
Thus , the results indicate the presence of severe emotional disturbances in children with TS and in their mothers . - pubmed
An anesthetic experience during open heart surgery in a patient with Budd - Chiari syndrome combined with superior vena cava syndrome : A case report . - pubmed
The patient was managed successfully without conventional intraoperative hemodynamic monitoring such as central venous catheterization , pulmonary artery catheterization , or transesophageal echocardiography due to underlying SVCS and the risk of varix bleeding . - pubmed
METHODS : Retrospective analysis of patients with hyperparathyroidism who have undergone Tc99m - sestamibi dual - time imaging and parathyroid surgery . - pubmed
RESULTS : A total of 135 hyperparathyroidism patients met the inclusion criteria . - pubmed
RESULTS : The prevalence of peri - implantitis over an average follow - up of 2 years was 34 % on the patient level and 21 % on the implant level . - pubmed
CONCLUSIONS : Approximately 1/3 of the patients and 1/5 of all implants experienced peri - implantitis . - pubmed
Effect of Cyclocarya Paliurus on Hypoglycemic Effect in Type 2 Diabetic Mice . - pubmed
The DM mice were divided into 3 groups : a DM group , a DM+CPE ( 0.5 g / Kg ) group , and a DM+CPE ( 1.0 g / Kg ) group . - pubmed
Anxiolytic and stimulant drugs facilitated learning at doses which did not impair locomotion , suggesting that pharmacological manipulation of other factors in addition to fear / anxiety can impact aversive learning in zebrafish . - pubmed
Clinical Utility of Targeted Next - Generation Screening of Peripheral Blood in the Evaluation of Patients with Cytopenias . - pubmed
A total of 58 ( 80.55 % ) patients had acute infarction lesions on the diffusion weighted imaging ( DWI ) . - pubmed
After 3 months of follow - up , two patients had recurrent ischemic stroke . - pubmed
Regardless of the high frequency of infarction in CWS patients , more than 80 % patients had a favorable functional prognosis . - pubmed
Cervical internal carotid artery tortuosity : A morphologic analysis of patients with acute ischemic stroke . - pubmed
BACKGROUND AND PURPOSE : Cervical internal carotid artery ( ICA ) tortuosity is thought to impede distal catheterization during attempted mechanical thrombectomy in patients with acute ischemic stroke . - pubmed
METHODS : A retrospective review was completed of neck CTAs of patients with acute ischemic stroke due to a large vessel occlusion that underwent attempted endovascular recanalization . - pubmed
Effect of Changing Diet on Gastric Ulceration in Exercising Horses and Ponies After Cessation of Omeprazole Treatment . - pubmed
Diet is an accepted risk factor for equine squamous gastric disease ( ESGD ) , but there is little published evidence for the benefit of dietary change ( DC ) . - pubmed
Our data showed that ALA but not LA supplementation alleviated systolic blood pressure elevation and improved ACh - induced , endothelium - dependent vasodilation in both spontaneously hypertensive rats ( SHRs ) and AngII - induced hypertensive mice . - pubmed
Liver biopsy remains the gold standard in evaluating NASH ; however , noninvasive methods are accumulating evidence for a growing role in identifying patients at increased risk to develop NASH , fibrosis , and potentially cirrhosis . - pubmed
Interestingly , new research in animal models of HGPS has demonstrated impressive lifespan improvements secondary to metabolic interventions . - pubmed
CONCLUSION : This is the first systematic assessment of TAVR for elderly patients with aortic stenosis . - pubmed
Accommodation and stereopsis in adults with traumatic brain injury . - pubmed
The aim of this study is to evaluate accommodation , stereopsis deficits and visual symptoms in Chinese patients with traumatic brain injury . - pubmed
METHODS : This is a cross - sectional study that included 22 patients with traumatic brain injury and 22 controls ; the refractive status , stereoacuity , and accommodative ability of each subject were measured . - pubmed
RESULTS : Patients with traumatic brain injury were significantly more symptomatic than controls ( p < 0.001 ) . - pubmed
Near stereoacuity thresholds were significantly elevated in patients with traumatic brain injury compared to controls ( p < 0.001 ) . - pubmed
Patients with traumatic brain injury showed greater accommodative lag to 2.5 D ( p = 0.03 ) , 3 D ( p = 0.03 ) , 4 D ( p = 0.004 ) and 5 D ( p = 0.001 ) stimuli , but not to the 2 D ( p = 0.10 ) stimulus . - pubmed
CONCLUSION : Patients with traumatic brain injury have deficits in accommodation and stereopsis . - pubmed
A 59 - year - old man , with a background of multiply relapsed myeloma , presented with a 3 - week history of confusion , short - term memory impairment and behavioural changes . - pubmed
We present this case as an example of PML in a patient with multiple myeloma , highlighting the need to consider this diagnosis in an enlarging population of heavily treated , severely immunocompromised , patients . - pubmed
The aim of the study was to evaluate the alteration in the expression of these biomarkers in a group of autism spectrum disorder ( ASD ) children . - pubmed
Peripheral blood mononuclear cells ( PBMCs ) were obtained from 37 autistic patients . - pubmed
changes regardless of the direction ) of miR-181b were significant in autistic children . - pubmed
Furthermore , tumor xenograft models in nude mice were established to test tumor growth and weight . - pubmed
MATERIALS AND METHODS : Between 2000 and 2014 , a total of 284 T4 - NSCLC patients who underwent lung resection ( mediastinal organ invasion , n = 114 ; ipsilateral different lobe tumors , n = 32 ; and tumors larger than 7 cm , n = 138 ) were included in the present study . - pubmed
The 5 - year survival rates were 46 % for ipsilateral different lobe tumors , 45.4 % for tumours larger than 7 cm , and 36.6 % for mediastinal organ invasion ( 28 % for patients with heart / atrium invasion , 43.3 % for carina invasion , 37.5 % for large vessel invasion ) ( p = 0.223 ) . - pubmed
CONCLUSION : According to the results of our study , surgical treatment is a good option in T4 - NSCLC patients who have no mediastinal lymph node metastasis and are completely resectable . - pubmed
Helicobacter pylori monoclonal strains were isolated from patients with eradication failure . - pubmed
Tofacitinib is approved for the treatment of moderate to severe active rheumatoid arthritis ( RA ) in adult patients who do not respond adequately or are intolerant to one or more disease - modifying anti - rheumatic drugs . - pubmed
Embolectomy was performed in the remaining four patients for the treatment of acute ischemia of the extremities . - pubmed
This retrospective study was designed to evaluate the risk factors and outcomes of patients with severe stenosis of the SA who underwent PTAS complicated by aortic dissection . - pubmed
All patients had hypertension and a high severity of SA stenosis ( 85.0 + - 13.0 % , 60 - 95 % ) . - pubmed
All patients had spontaneous resolution of the aortic dissection with conservative treatment . - pubmed
A 29 - year - old man with a marfanoid habitus , peculiar mucosal neuromas of the lips and tongue , high arched palate , hyperplastic corneal nerves , and hypertension was found at operation to have medullary carcinoma of the thyroid , parathyroid hyperplasia , and pheochromocytoma . - pubmed
The eradication of bovine brucellosis in New Zealand : History and objectives . - pubmed
A double - blind controlled study of seratonin uptake inhibitor ( Zimelidine ) versus placebo in chronic pain patients . - pubmed
Forty patients with pain syndromes of both organic and psychogenic origin of at least 6 months ' duration were included in a double - blind controlled study of a new rather selective serotonin uptake inhibitor , Zimelidine , versus placebo . - pubmed
Patients in the Zimelidine group experienced significantly more pain relief and tended to be able to reduce their need for analgesics more often than the patients in the placebo group . - pubmed
In the Zimelidine group 4 patients were excluded due to nausea and intestinal troubles versus only 1 patient in the placebo group . - pubmed
[ Sex ratio of inbred strains of mice ] . - pubmed
A study of the sex ratio in mice of the inbred strains ( CBA and C3H ) and connection of the postimplantation embryonic mortality in mice of these strains with the sex distribution of embryos demonstrated that the sex ratio in these mice was 1:1 . - pubmed
Literature and the author 's personal data suggested that genetic features of mice of the inbred strains failed to influence significantly the sex ratio of the offspring . - pubmed
The postimplantation embryonic death rate in the C3H mice exceeded that in the CBA mice ( 14.4 and 9.3 % , respectively ) . - pubmed
However , the balanced sex ratio in mice of these strains points to the absence of selective mortality of the embryos of any one sex during embryogenesis . - pubmed
In order to localize bronchodilators site of activity we studied the maximal expiratory flow - volume curves breathing air and 80 percent-20 percent helium - oxygen mixture in 11 normal and 23 asthmatic children . - pubmed
Oral antibiotic therapy for skeletal infections of children . - pubmed
Peak synovial fluid concentrations were greater than 60 % of peak serum concentrations with all drugs tested and there was adequate inhibitory activity against bacteria commonly causing arthritis . - pubmed
Estimation of ferrokinetic parameters by a mathematical model in patients with primary acquired sideroblastic anaemia . - pubmed
Ferrokinetic parameters were estimated in eight patients with primary acquired sideroblastic anaemia ( PASA ) by means of a mathematical model of iron kinetics . - pubmed
By using silicone rubber injections we have studied the blood supply to the cervical skin in human cadavers before and after the elevation of flaps . - pubmed
The lambs were treated with albendazole ( SmithKline Beecham ) , fenbendazole ( Hoechst Roussel ) or a vitamin supplement and their weight gains were followed over the next 7 months . - pubmed
This paper reports a series of 10 patients re - irradiated with external - beam techniques for local recurrence of soft - tissue sarcoma of the limb and limb girdle following initial limb conserving management with surgery and radiotherapy ( dose range 33 - 60 Gy ) . - pubmed
Five patients re - treated with radical intent ( dose range 40 - 60 Gy ) had a median survival of 36 months and median recurrence - free survival of 16 months . - pubmed
All five patients treated palliatively ( dose range 12 - 50 Gy ) have died , although two demonstrated local control until death . - pubmed
Radionecrosis was seen in one patient who was re - irradiated twice ( total dose 145 Gy ) and subsequently required amputation . - pubmed
Two hundred patients were randomly selected for either a partial or a total meniscectomy for a meniscal tear during open operation . - pubmed
Patients with bucket - handle , anterior and posterior horn tears had similar functional results after total meniscectomy . - pubmed
Maternal - iron - deficiency effects on peritoneal macrophage and peritoneal natural - killer - cell cytotoxicity in rat pups . - pubmed
Cytotoxicity of peritoneal macrophages ( pMs ) and peritoneal natural killer ( pNK ) cells toward xenogenic tumor cells was studied in anemic , suckling rats . - pubmed
A case is reported to reinforce that Entamoeba histolytica should be considered in the differential diagnosis of all patients presenting with liver abscess , whether they have travelled abroad or not . - pubmed
Instrumented near - term pregnant ewes received 1 - h maternal infusion of ethanol ( 1 g / kg maternal body weight ) followed 0.5 h later by a 3 - h fetal infusion of indomethacin ( 1 mg / kg fetal body weight / h ) , and then a 2 - h fetal infusion of PGE2 ( 400 ng / kg fetal body weight / min ) . - pubmed
Xanthine - containing urinary calculi in dogs given allopurinol . - pubmed
Clinical features and laboratory findings were evaluated in 10 dogs that formed xanthine - containing urinary calculi during the period that they were given allopurinol ( 9 to 38 mg / kg of body weight / d ) . - pubmed
Of the 10 dogs , 9 ( all Dalmatians ) had formed uric acid - containing calculi at least once before allopurinol treatment was initiated . - pubmed
Sodium , ATP , and intracellular pH transients during reversible complete ischemia of dog cerebrum . - pubmed
We examined the temporal relationships among transcellular sodium , energy metabolism , and intracellular pH with sodium and phosphorus magnetic resonance spectroscopy in a new , hemodynamically stable , brain stem - sparing model of reversible , complete cerebral ischemia in eight anesthetized dogs . - pubmed
This study was undertaken to reveal whether variations in oxygen supply in the postischemic period following forebrain ischemia in rats affect free radical production and the brain damage incurred . - pubmed
To that end , rats ventilated on N2O / O2 ( 70:30 ) were subjected to 15 min of transient ischemia . - pubmed
In a parallel series , animals ventilated with one of the three gas mixtures in the early recirculation period , respectively , were allowed to recover for 7 days , with subsequent perfusion - fixation of brain tissues and light microscopical evaluation of the brain damage . - pubmed
Hyperoxic animals failed to show increased tissue H2O2 production , while hypoxic ones showed a tendency towards decreased production . - pubmed
Several complications of antihypertensive therapy particularly threaten elderly hypertensive drugs patients . - pubmed
Hypotensive responses to tryptophan and 5 - hydroxytryptophan infusions were studied in normotensive male Sprague - Dawley rats . - pubmed
Pharmacokinetics of famotidine in elderly patients with and without renal insufficiency and in healthy young volunteers . - pubmed
Elimination half - life in the elderly patients with renal insufficiency was significantly prolonged compared to the elderly patients with normal renal function and the young volunteers . - pubmed
In a prospective study to determine the accuracy of intravenous DSA in the diagnosis of ulcerative lesions of the internal carotid artery , preoperative findings obtained from DSA in patients with suspected cerebrovascular disease were reviewed and compared with thrombendarterectomy specimen ( n = 74 ) . - pubmed
Four patients with oligoamenorrhea manifesting hormonal and clinical features of polycystic ovarian disease ( PCOD ) were selected for treatment . - pubmed
It may be assumed that either subcutaneous administration is inadequate in PCOD patients or that the frequency of pulses needed to correct the hormonal disturbances in PCOD patients differs from that needed for ovum maturation and ovulation . - pubmed
The findings on routine pre - operative palpation of the axilla in patients with infiltrative breast carcinoma are compared to the results of histological quantitation of the nodal lymphoid tissue and its tumour deposits in 91 consecutive cases in which a standardized axillary dissection had been carried out . - pubmed
The efficiency of spontaneous ventilation during halothane anaesthesia was investigated in 18 infants and children with congenital heart disease presenting either with hyperperfusion and left - to - right shunt ( group LR : n = 10 , body weight 3.7 - 16 kg ) or with hypoperfusion and right - to - left shunt ( group RL : n = 8 , body weight 3.4 - 12 kg ) . - pubmed
The mean Pr2 concentrations in eight patients with disseminated intravascular coagulation and six asymptomatic individuals with congenital antithrombin deficiency not receiving antithrombotic therapy were not significantly elevated as compared with those of normal controls ( 0.244 nmmol / L and 0.242 nmol / L vs. 0.184 nmol / L , respectively ) . - pubmed
Given that the t1/2 of F1 + 2 is estimated to be approximately 90 minutes , the low plasma levels of Pr2 observed in patients with thrombophilia can not result from rapid clearance of this component. - pubmed
In contrast , the hepatocytes of animals that drank the 3 % glucose solution did not display the rarefied hyaloplasm or disorientation of cellular organelles and resembled the hepatocytes of control animals . - pubmed
[ Intracranial blood volume during gravitational stress in rats adapted to hypoxia ] . - pubmed
Thirty - four patients admitted for a suspicion of septicaemia were treated with ceftriaxone , a third generation cephalosporin . - pubmed
The only observed secondary effect was a drug fever occurring in 3 patients who remained febrile in spite of a general improvement . - pubmed
[ Clinical significance of stress - induced ST segment changes in patients with previous myocardial infarction : evaluation by 201Tl myocardial single photon emission computed tomography ] . - pubmed
The disrupting action of neuroleptic haloperidol on the amphetamine - induced stereotype is weakened in animals with ventral lesions and enhanced in those with dorsal lesions . - pubmed
The data obtained and the clinical trials carried out by the authors suggest introduction of the physiological doses of thiamine , calcium pantothenate and ascorbic acid into the diet of the workers in order to prevent phenol poisonings more effectively . - pubmed
Treatment of fears and phobias in dogs . - pubmed
Left ventricular performance in endotoxin shock in dogs . - pubmed
Because of reports of late deterioration , we studied six dogs until spontaneous death ( 9 - -18 h ) . - pubmed
Six couples with immunologic infertility were treated with corticosteroids . - pubmed
are Gram - negative non - fermentative bacteria which may be isolated as commensals from human skin , throat and intestine but are also increasingly responsible for hospital infections . - pubmed
Owing to frequent changes in their taxonomy , their pathogenic role in humans has not been clear but today acinetobacter is considered to be a significant nosocomial pathogen in outbreaks of hospital infections predominantly in intensive care units . - pubmed
A 55 - kilodalton antigen encoded by a gene on a Borrelia burgdorferi 49 - kilobase plasmid is recognized by antibodies in sera from patients with Lyme disease . - pubmed
burgdorferi DNA expression library ( N40 strain ) with rabbit anti - B. - pubmed
Of 11 enterotoxigenic strains , 7 were A. - pubmed
Genes specifying identical activities were detected in various strains of L. - pubmed
We report a prospective study of 46 patients with acute complete dislocation of the acromioclavicular joint . - pubmed
Follow - up was from 2 to 7.9 years ( mean 5.8 ) , and at the latest review only five patients ( 10.9 % ) had redisplacement , due to premature removal of wires for infection in one , to migration of the wires in another and to partial failure of the muscle repair in three . - pubmed
There has been an explosion in our understanding of how nerve cells in mammals respond to O2 deprivation and what are the mechanisms involved in nerve cell injury or survival . - pubmed
Further , we have characterized the distribution of these receptors / channels complexes in the CNS of the rat and in an anoxia - resistant animal : the turtle . - pubmed
Surgical resection of adenomas cures in most patients with the disorder . - pubmed
Droloxifene inhibits cortical bone turnover associated with estrogen deficiency in rats . - pubmed
Droloxifene ( DRO ) , an estrogen antagonist / agonist , has been shown to possess estrogen - like effects in inhibiting bone turnover leading to cancellous bone loss in ovariectomized ( OVX ) rats . - pubmed
Endogenous opioid tone in patients with rheumatoid arthritis . - pubmed
Seven RA patients with active and established disease and eight healthy controls were studied . - pubmed
Stuffed animals as a bedside clinical clue may suggest evaluation for Borderline Personality Disorder . - pubmed
Sham - operated controls and unoperated rats that had been pre - exposed to a light stimulus prior to light - shock pairings showed less conditioned suppression towards the light stimulus than the nonpre - exposed animals , thus demonstrating LI . - pubmed
In this retrospective study , oncologic and functional results of 24 patients treated for glomus jugulare tumor stages C and D are reported . - pubmed
Surgically induced cranial nerve palsies developed in 38 % of the patients . - pubmed
Seven patients had incomplete tumor removal requiring postoperative irradiation , with tumor progression occurring in 2 patients . - pubmed
Reactivity of the basilar artery was measured in untreated nondiabetic and diabetic rats and in nondiabetic and diabetic rats treated with a daily intraperitoneal injection of dimethylthiourea ( DMTU ; 50 mg / kg ) . - pubmed
Dilatation of the basilar artery in response to nitroglycerin was similar in untreated and DMTU - treated nondiabetic and diabetic rats . - pubmed
The C6 glioma in the immune - competent rat is a frequently used model in brain tumor gene therapy research . - pubmed
It displays the histologic hallmarks of the human glioblastoma and has been employed to demonstrate new mechanisms of anti - tumor immunity and therapeutic strategies . - pubmed
We noted that C6 tumors regressed spontaneously in three of five animals and that protective anti - tumor immunity ensued without therapeutic intervention . - pubmed
A review of the literature revealed that different rat strains are used as " syngeneic " host for the C6 cell glioma , namely , BDIX , BDX , Sprague - Dawley , and Wistar . - pubmed
These data suggest that the C6 glioma model in the immune - competent rat should no longer be used to study gene therapy strategies , that the available data obtained in this model need to be critically reinterpreted , and that findings obtained in the C6 glioma model may not be sufficient to support a clinical trial in glioblastoma patients . - pubmed
The technique of lymphoscintography was initially used to identify the sentinel node / s in patients with malignant melanoma . - pubmed
A proposed alternative management strategy to routine axillary lymph node dissection in patients with breast cancer is sentinel lymph node localization using lymphoscintography and biopsy of the identified sentinel node . - pubmed
Loss of tolerance to amphetamine - induced hypophagia in rats : homeostatic readjustment vs. instrumental learning . - pubmed
Allergy to grapes . - pubmed
To avoid the expression of dyskinesias in already primed patients , agents that act on either the dopamine or nondopaminergic receptors have been used . - pubmed
Letrozole for the treatment of pretreated advanced breast cancer patients : preliminary report . - pubmed
Twenty patients ( pts ) with metastatic breast cancer with disease progression , previously treated with chemotherapy and tamoxifen , were administered oral letrozole ( 2.5 mg / day ) therapy . - pubmed
These results suggest that the in vitro sperm - egg interaction assay accurately reflects the fertilizing ability of fresh and stored duck spermatozoa and detects spermatozoal damage due to semen storage more sensitively than motility or fertility tests . - pubmed
RESULTS : Of 414 patients with suspected upper gastrointestinal bleeding , 379 were endoscoped . - pubmed
CONCLUSIONS : Blood in the stomach reflects clinical features in patients with acute upper gastrointestinal bleeding and is reduced by treatment with lansoprazole and tranexamic acid . - pubmed
Bifidobacteria populations in fermented milks should be over 10(6 ) bifidobacteria / g at the time of consumption of strain added to the product . - pubmed
OBJECTIVES : Hypopituitary adults with growth hormone deficiency ( GHD ) have an increased cardiovascular mortality , although the mechanisms remain unclear . - pubmed
The influence of two concentrations of sodium hypochlorite on human blood : changes in haemolysis , pH and protein . - pubmed
Blood concentrations of cyclosporin a during long - term treatment with cyclosporin a ophthalmic emulsions in patients with moderate to severe dry eye disease . - pubmed
To quantify blood cyclosporin A ( CsA ) concentrations during treatment with CsA topical ophthalmic emulsions , blood was collected from 128 patients enrolled in a Phase 3 , multicenter , double - masked , randomized , parallel - group study of CsA eyedrops for treatment of moderate to severe dry eye disease . - pubmed
The near - isogenic line ( NIL ) TA1150 contains a 56 - cM introgression from Lycopersicon chmielewskii chromosome 1 and has several interesting phenotypic characteristics including fruit with orange color , high levels of soluble solids , thick pericarp , small stem scars , and good firmness . - pubmed
It is concluded that there is a higher risk of developing cervical dysplasia in HIV - seropositive women who carry the human papillomavirus . - pubmed
Phase I trial of tirapazamine and cyclophosphamide in children with refractory solid tumors : a pediatric oncology group study . - pubmed
One child with neuroblastoma had prolonged stable disease ( 10 cycles ) at a dose of 250 mg / m(2 ) . - pubmed
This patient had disease detectable in the bone marrow only and all evidence of bone marrow involvement resolved for 17 cycles of therapy . - pubmed
However , these guidelines can be questioned with regard to the extent of efficacy as well as the rationale for not using strong opioids as first - line treatment , especially in terminal cancer patients . - pubmed
The purpose of this randomized study was to prospectively compare the efficacy and tolerability of strong opioids as first - line agents with the recommendations of the WHO in terminal cancer patients . - pubmed
One hundred patients with mild - moderate pain were randomized to treatment according to WHO guidelines or to treatment with strong opioids . - pubmed
Evaluated outcomes included pain intensity , need for change in therapy , quality of life , Karnofsky Performance Status , general condition of the patient , and adverse events . - pubmed
No between - treatment differences were observed for changes in quality of life or performance status , but patients started on strong opioids had significantly better pain relief than patients treated according to WHO guidelines ( P=0.041 ) . - pubmed
Additionally , patients started on strong opioids required significantly fewer changes in therapy , had greater reduction in pain when a change was initiated , and reported greater satisfaction with treatment than the comparator group ( P=0.041 ) . - pubmed
These data suggest the utility of strong opioids for first - line treatment of pain in patients with terminal cancer . - pubmed
This analysis indicates that once - daily dosing ( 7 mg / kg ) of gentamicin should achieve satisfactory concentration in patients with normal renal function although serum concentration monitoring is required to confirm the optimal dosing interval in patients with impaired renal function . - pubmed
DESIGN AND METHODS : Fifty - five patients with ET were evaluated . - pubmed
Pain - related fear and daily functioning in patients with osteoarthritis . - pubmed
In the current study , the authors investigated this hypothesis in patients with bladder carcinoma . - pubmed
OBJECTIVE : The objective was to investigate associations between dietary macronutrients and progression of coronary atherosclerosis among postmenopausal women . - pubmed
DESIGN : Quantitative coronary angiography was performed at baseline and after a mean follow - up of 3.1 y in 2243 coronary segments in 235 postmenopausal women with established coronary heart disease . - pubmed
METHODS : This study reviewed 298 scoliosis patients ( 107 male , 191 female ) who underwent anterior and/or posterior operation . - pubmed
On the other hand , the presence of the strain did not interfere with the growth of certain species of normal intestinal microbiota , such as Enterococcus fecalis , Escherichia coli , Bifidobacterium bifidum or Bacteroides fragilis . - pubmed
We reviewed 61 hips in 50 children ( 33 boys and 17 girls ) with slipped capital femoral epiphysis ( SCFE ) , all treated by in situ pinning . - pubmed
The authors critically reviewed the medical literature on SSRIs to identify subgroups of patients at risk of bleeding complications . - pubmed
In this study , we modelled the drugs used in practice on human prostate cancer cell lines . - pubmed
With the use of various cytostatics , the cell proliferation - inhibiting effects were measured under in vitro conditions on human prostate cancer cell lines LNCaP - FGC and PC-3 . - pubmed
METHODS : Pulpal necrosis was induced in foxhounds along with surgical removal of radicular buccal bone . - pubmed
OBJECTIVE : The aim of the study was to determine whether the forced oscillation technique ( FOT ) , which does not require active cooperation , may be useful to assess bronchial responsiveness in patients with suspected occupational asthma ( OA ) . - pubmed
METHODS : Changes in resistances evaluated by FOT , and DeltaFEV1 measured during methacholine challenge test were compared in 77 adults referred for suspected OA . - pubmed
The study group included 20 adult patients ( 9 men , 11 women , mean age 57.2 years ) with ASD who had undergone successful closure with the Amplatzer occluder . - pubmed
Two patients complained of amaurosis fugax at 1 and 3 months after the procedure , and two patients complained of blurred vision at 3 and 4 months after the procedure . - pubmed
In conclusion , microembolic events do not appear to be the cause of the ocular complaints in patients with ASD treated with Amplatzer occluder . - pubmed
We present an unusual case of a patient with an acute retrobulbar optic neuropathy , secondary to a ruptured anterior communicating artery aneurysm . - pubmed
METHODS : A 29 - year - old woman was assessed for an acute , isolated unilateral optic neuropathy of unknown origin . - pubmed
Although an initial encephalic MRI was believed to be normal , an underlying ruptured anterior communicating artery aneurysm was eventually diagnosed when the patient became stuporous because of intracranial bleeding . - pubmed
DESIGN AND METHODS : We investigated 136 newly diagnosed APL patients from four Italian Institutions . - pubmed
INTERPRETATION AND CONCLUSIONS : Our findings suggest that immunophenotypic analysis can distinguish a subset of APL patients with different biological characteristics . - pubmed
Salmonella was lodged mainly in the mid- and hindgut 3 days after the infective meal , minimizing transmission through vomit . - pubmed
Topical gene transfer to the airways of cystic fibrosis ( CF ) patients has been inefficient , partly due to extracellular barriers such as sputum . - pubmed
CASE REPORT : We report on a 76 - year - old patient who presented with an atypical hydrocele testis . - pubmed
Administered with sorbitol , it usually has minor adverse effects , but it may cause colonic or intestinal necrosis in uremic patients . - pubmed
We report an unusual case of rectal stenosis due to SPS crystals in a 46 - year - old man . - pubmed
The patient had been involved in a car accident with severe thoracic and abdominal trauma . - pubmed
The combination of plasmapheresis with these cytotoxic agents and steroids is effective in patients with Goodpasture ' s syndrome , especially if instituted early in the course of the disease . - pubmed
Recent evidence suggests that patients with severe ANCA - associated vasculitis , defined by the presence of diffuse alveolar haemorrhage and/or severe renal involvement ( creatinine concentration & gt ; 5.7 mg / dl ) , might benefit from plasma exchange in combination with cyclophosphamide and corticosteroids . - pubmed
The HIV epidemic in China has been increasing exponentially , yet there have been no studies of the neurobehavioral effects of HIV infection in that country . - pubmed
Ultrasound - doppler coupled with gadolinium - enhanced MR or CT angiography has proven adequate for most patients with RAS . - pubmed
Stenting completed angioplasty is worthwhile in most patients with atherosclerotic RAS . - pubmed
ACE inhibitors decrease mortality and increase renal function in patients with RAS . - pubmed
Higher infection of dengue virus serotype 2 in human monocytes of patients with G6PD deficiency . - pubmed
Human monocytes from peripheral mononuclear cells collected from 12 G6PD - deficient patients and 24 age - matched controls were infected with one of two DENV serotype 2 ( DENV-2 ) strains - the New Guinea C strain ( from a case of dengue fever ) or the 16681 strain ( from a case of dengue hemorrhagic fever ) with a multiplicity of infection of 0.1 . - pubmed
Experimental results indicated that the monocytes of G6PD - deficient patients exhibited a greater levels of infection with DENV-2 New Guinea C strain than did those in healthy controls [ mean+/-SD:33.6%+/-3.5 ( 27.2 % approximately 39.2 % ) vs 20.3%+/-6.2 ( 8.0 % approximately 30.4 % ) , P<0.01 ] . - pubmed
Similar observations were made of infection with the DENV-2 16681 strain [ 40.9%+/-3.9 ( 35.1 % approximately 48.9 % ) vs 27.4%+/-7.1 ( 12.3 % approximately 37.1 % ) , P<0.01 ] . - pubmed
To our knowledge , this study demonstrates for the first time higher infection of human monocytes in G6PD patients with the dengue virus , which may be important in increasing epidemiological transmission and perhaps with the potential to develop more severe cases pathogenically . - pubmed
Thresholds of risk factors for ischemic stroke in type 2 diabetic patients with and without albuminuria : a non - linear approach . - pubmed
PATIENTS AND METHODS : This is a prospective cohort study with 6969 Chinese type 2 diabetic patients without history of stroke after a median follow - up of 5.36 years . - pubmed
We sought to identify pharmacodynamic factors involved in partial desmopressin response or desmopressin resistance in children with monosymptomatic nocturnal enuresis , with special emphasis on concentrating performance , and time to reach and duration of maximal urine concentration . - pubmed
MATERIALS AND METHODS : We evaluated 64 children with monosymptomatic nocturnal enuresis and proved nocturnal polyuria lacking full response to desmopressin treatment . - pubmed
After an oral fluid load given at the start of the test the majority of patients failed to reach maximal concentration of urine as voided during hydropenia , and 45 patients failed to regain appropriate dilution of urine even when an oral water load of 15 ml / kg ( urine osmolality less than 750 mOsmol / l ) was given in the morning at the end of the test . - pubmed
Cardiovascular and autonomic phenotype of db / db diabetic mice . - pubmed
The db / db mice serve as a good model for type 2 diabetes characterized by hyperinsulinaemia and progressive hyperglycaemia . - pubmed
OBJECTIVE : To determine the frequency and possible cognitive effect of histological Alzheimer ' s disease ( AD ) in autopsied older nondemented individuals . - pubmed
STUDY DESIGN : All trauma patients admitted from January 2005 to April 2007 in a Level I trauma center were divided into a nondelayed ( & lt;or=6 hours ) group or a delayed ( & gt;6 hours ) group . - pubmed
Hospitals with a large trauma / emergency general surgery caseload resulting in delays in ED throughput should institute policies and procedures for triage of more severely injured patients for early ICU admission and develop a monitoring system to ensure that delays do not adversely affect patient outcomes . - pubmed
We investigated the antioxidant effect of different extracts of non - transformed ( S ) and transformed pineapple ( with the magainin gene construct , [ TS ] , for disease resistance ) . - pubmed
Use of quantum dots to detect human papillomavirus in oral squamous cell carcinoma . - pubmed
OBJECTIVE : To examine the association of oral squamous cell carcinoma with human papillomavirus ( HPV ) using quantum dots ( QD ) in situ hybridization ( ISH ) . - pubmed
METHODS : Expression of HPV16/18 was analyzed in a representative collection of 21 oral squamous cell carcinomas by tissue microarrays . - pubmed
RESULTS : Seven cases out of 21 ( 33.3 % ) were positive for QDISH while 1 out of 21 ( 4.8 % ) was positive for ISH , although all of HPV DNA were localized in the nuclei in the spinous and basal cell layer of the epithelium . - pubmed
OBJECTIVES : The aim of this study was to investigate the determinants of serum total homocysteine level ( tHcy ) in patients with type 2 diabetes mellitus ( DM ) according to sex . - pubmed
Fifteen patients with PD performed index finger , hand tapping and horizontal pointing movements as well as reach - to - grasp movements with either hand before ( baseline conditions ) and after a period of 1 Hz rTMS preconditioned by ( 1 ) sham , ( 2 ) anodal or ( 3 ) cathodal tDCS over the primary motor cortex contralateral to the more affected body side . - pubmed
We used pseudoislets self - organized from a population of the insulinoma cell line MIN6 , derived from a transgenic mouse expressing the large T - antigen of SV40 in pancreatic beta - cells , as an experimental model for the study of cell nanoencapsulation . - pubmed
Although specific mediators of hepatic lipotoxicity have not been identified with certainty , abundant evidence from animal studies and recent data in humans indicate that free fatty acids in the liver can serve as substrates for formation of nontriglyceride lipotoxic metabolites that cause liver injury . - pubmed
In this study , we examined the roles of phosphatidylinositol 4,5 - bisphosphate [ PI ( 4,5 ) P ( 2 ) ] and PI ( 4,5 ) P ( 2 )-producing enzymes in invadopodia formation in MDA - MB-231 human breast cancer cells . - pubmed
The cumulative incidence of severe AKI within 100 days in patients with an HCT - CI score 0 , 1 - 2 , and & gt;=3 was 21.3 % , 48.8 % , and 73.9 % , respectively . - pubmed
The purpose of this study was to investigate the clinical factors predictive of bacteremia in low - risk febrile neutropenia at initial patient evaluation . - pubmed
Patients who met the criteria of low - risk febrile neutropenia at the time of visit to emergency department after anti - cancer chemotherapy were included in the analysis . - pubmed
Patients with low score points had low rate of bacteremia , thus , would be candidates for outpatient - based or oral antibiotic therapy . - pubmed
We present a clinical case of a 63 years old patient with abdominal pain and weight loss . - pubmed
We observed a significant decrease in DA concentrations in the ME and hyperprolactinemia in an exposure - dependent manner similar to that seen in OCE rats . - pubmed
Refractive error and visual functions in children with special needs compared with the first grade school students in oman . - pubmed
A pediatrician reviewed the health records of all the children at the time of their enrollment in this study to determine if the child had been diagnosed with a systemic condition or syndromes . - pubmed
We estimated the rates and the risk of different visual function defects in children with special needs . - pubmed
RESULT : The prevalence of refractive error in 70 children ( 4.7 + - 0.8 years ) with special needs ( group 1 ) and 175 normal healthy first grade students ( group 2 ) were 58.5 % and 2.9 % , respectively . - pubmed
Six children in this group had defective near vision . - pubmed
Sixteen ( 80 % ) children with Down syndrome had refractive error . - pubmed
Seven ( 50 % ) children with developmental disorder showed decreased contrast sensitivity . - pubmed
CONCLUSION : Prevalence of uncorrected refractive error was much higher in children with special needs . - pubmed
Prevalence of strabismus , nystagmus , and reduced contrast sensitivity was also higher in children with special needs . - pubmed
We present a child with neuroblastoma , successfully treated without radiation therapy , who developed mid - aortic syndrome and hypertension . - pubmed
The incidence of mid - aortic syndrome in children with neuroblastoma is unknown . - pubmed
RESULTS : For glioblastoma patients in the ALA study , median survival was 16.7 and 11.8 months for complete versus partial resection , respectively ( P & lt ; 0.0001 ) . - pubmed
For glioblastoma patients who received & gt;=90 % resection in the BCNU wafer study , median survival increased for BCNU wafer versus placebo ( 14.5 versus 12.4 months , respectively ; P = 0.02 ) , but no survival increase was found for & lt;90 % resection ( 11.7 versus 10.6 months , respectively ; P = 0.98 ) . - pubmed
METHODS : Eight RA patients with a disease duration & lt ; or = 1 year received 40 mg adalimumab subcutaneously every 2 weeks . - pubmed
It also ameliorated carotid atherosclerosis and arterial stiffness in patients with early RA . - pubmed
PATIENTS : 325 patients with CAD requiring cardiovascular surgery with an ASA of III or above . - pubmed
HHV-8 - associated multicentric Castleman ' s disease in HIV - negative patient : a novel therapy for an orphan disease . - pubmed
Photodynamic therapy using a novel photosensitizer , TONS501 , is similarly effective to ALA and EC036 photodynamic therapy on DMBA - and TPA - induced mouse skin papilloma . - pubmed
OBJECTIVE : Using 7 , 12 - dimethylbenz [ a ] anthracene ( DMBA ) and 12 - omicron - tetradecanoylphorbol-13 - acetate ( TPA)-induced mouse skin papilloma model , we compared the efficacy of ALA- , TONS501- , and TONS504 - PDT on the skin tumor regression . - pubmed
METHODS : Following application of ALA , TONS501 , TONS504 ointment or TONS501 lotion on DMBA- and TPA - induced mouse papillomas , 670 nm laser irradiation by LD670 - 05 diode laser was performed . - pubmed
CONCLUSION : A novel TONS501ointment - PDT shows potent anti - tumor effect on DMBA- and TPA - induced mouse skin papilloma and might be more useful for the clinical applications . - pubmed
Newcastle disease ( ND ) is a highly contagious , severe disease of poultry caused by pathogenic strains of Newcastle disease virus ( NDV ; or avian paramyxovirus-1 ) . - pubmed
Most of the published strains are outbreak - associated strains , while the apathogenic NDV strains that occur in wild birds , posing a constant threat to poultry with their capability to convert into more virulent forms , have remained less studied . - pubmed
Animal models of antipsychotic - related weight gain and animal transgenic models of knockout or overexpressed genes of antipsychotic receptors have been largely evaluated by scientific community for changes in obesity - related gene expression or phenotypes . - pubmed
In this paper , we summarize current thinking on : ( 1 ) the role of polymorphisms in several candidate genes , ( 2 ) the possible roles of various neurotransmitters and neuropeptides in this adverse drug reaction , and ( 3 ) the state of development of animal models in this matter . - pubmed
The patient was managed in a single session with a combination of classic open surgical and endovascular techniques in order to treat his aneurysms and revascularize his leg . - pubmed
Evolutionary history of human disease genes reveals phenotypic connections and comorbidity among genetic diseases . - pubmed
In this work , we report that phenotypically similar diseases are connected by the evolutionary constraints on human disease genes . - pubmed
Human disease groups can be classified into slowly or rapidly evolving classes , where the diseases in the slowly evolving class are enriched with morphological phenotypes and those in the rapidly evolving class are enriched with physiological phenotypes . - pubmed
Furthermore , the high comorbidity found between diseases connected by similar evolutionary constraints enables us to improve the predictability of the relative risk of human diseases . - pubmed
We find the evolutionary constraints on disease genes are a new layer of molecular connection in the network - based exploration of human diseases . - pubmed
Which patients are at a high risk of ASC and need emergency drainage is still unclear . - pubmed
METHODS : We analyzed 359 consecutive patients with acute cholangitis who had been admitted to the First Affiliated Hospital , Zhejiang University School of Medicine from January 2004 to May 2011 . - pubmed
Of the remaining 358 patients with an average age of 62.7 years ( range 17 - 90 ) , 162 were diagnosed with ASC , and 196 with non - ASC . - pubmed
Complications were identified in 11 patients ( 3.1 % ): mild pancreatitis occurred in 8 patients and hemorrhage in 3 patients . - pubmed
In this work , Artemia franciscana was used as test organism model , studying mortality against several strains of M. - pubmed
Adrenal insufficiency in a peritoneal dialysis patient taking megestrol acetate . - pubmed
Case 35 - 2012 : A man with weakness , anorexia , and diffuse pain . - pubmed
[ Application of levosimendan in acute heart failure patients with symptoms of low cardiac output : case series report ] . - pubmed
The report presents single centre experience in application of levosimendan in patients with acute heart failure with low cardiac output . - pubmed
METHODS : Patients undergoing aneurysmal repair at two neurovascular referral centres between September 2005 and August 2010 were included ; patients who underwent coiling for recurrences of prior microneurosurgical clipping were excluded . - pubmed
We present the case of a 28 - year - old woman with postoperative pathologically - proven LCAS with right liver metastases . - pubmed
The butanol fermentation using solventogenic clostridial strains , particularly Clostridium acetobutylicum , is a very old industrial process ( acetone - butanol - ethanol - ABE fermentation ) . - pubmed
In this review , some newly engineered solvent - producing Clostridium strains are described and strains of which sequences are available are compared with C. - pubmed
Dynamic contrast - enhanced and diffusion - weighted magnetic resonance imaging noninvasive evaluation of vascular disrupting treatment on rabbit liver tumors . - pubmed
The purpose of the study is to evaluate consecutive changes of 20 rabbit VX2 liver tumors after VDT by dynamic contrast - enhanced MRI ( DCE - MRI ) and diffusion - weighted imaging ( DWI ) at a 3.0 T MR unit . - pubmed
We report a postmenopausal woman , who experienced two episodes of TCM within 4 months following emotional and physical stress . - pubmed
PATIENTS AND METHODS : This cross - sectional study was carried out on ESRD patients treated with HD in Imam Khomeini Hospital , Ahvaz city , Southwest of Iran . - pubmed
RESULTS : Out of 47 ESRD patients , 27 were male ( 57.4 % ) and 20 were female ( 42.6 % ) , with mean age of 55.27 + - 8.1 years . - pubmed
The mean time of HD in HEV positive and negative patients were 1224.2 and 1168.5 days , respectively with no significant association ( P = 0.88 ) . - pubmed
Herein , we report on three patients with gastric cancer in remnant stomach who underwent laparoscopic total gastrectomy with intracorporeal esophagojejunostomy successfully . - pubmed
Our experience has suggested that laparoscopic total gastrectomy with intracorporeal esophagojejunostomy can be a safe , feasible and promising option for patients with gastric cancer in remnant stomach . - pubmed
In this work , biosurfactant production by a Pseudomonas aeruginosa strain was optimized using low - cost substrates . - pubmed
Among the known human HEV strains ( genotypes 1 , 2 , 3 and 4 ) , the genotype 2 Mexican isolate has two ' double - base ' substitutions ( 5'U5100G5101 CU/3'C5117U5118 GG ) flanking the conserved cis - reactive element ( CRE ) in the intergenic - junction sequences . - pubmed
Multiple sequence alignment of intergenic - junction of human HEV strains showed further base conservations flanking the CRE sequences . - pubmed
Here , we provide laboratory evidence that net ( gross calcification minus dissolution ) and gross calcification rates of three common cold - water corals , Caryophyllia smithii , Dendrophyllia cornigera , and Desmophyllum dianthus , are not affected by pCO2 levels expected for 2100 ( pCO2 1058 muatm , Omegaara 1.29 ) , and nor are the rates of skeletal dissolution in D. - pubmed
Reply : Coxiella burnetii and complicated atherosclerosis : perhaps neither innocent nor bystanders . - pubmed
Although significant advances have been made in treatment for ccRCC , a significant percent of patients have no benefit from currently available treatment option . - pubmed
A total of 43 % of bronchoscopic examinations were nondiagnostic for lung cancer , and invasive procedures were performed after bronchoscopy in 35 % of patients with benign lesions . - pubmed
[ Relationship between blood pressure , heart rate and cardiac autonomic dysfunction in non - diabetic obese patients ] . - pubmed
Cardiac autonomic dysfunction ( CAD ) affects a high proportion of obese patients . - pubmed
Our aim was to examine the relationship between CAD , HR and BP in obese patients without known diabetes . - pubmed
PATIENTS AND METHODS : We included 428 overweight or obese patients . - pubmed
CONCLUSION : These data indicate that among overweight or obese patients with a defect in cardiac vagal activity BP is elevated only in those with a high heart rate , which is indicative of a more marked insulin resistance and probably an excess in sympathetic activity . - pubmed
The etiological agent that was most frequently isolated from materials gathered from patients diagnosed with SSI , BSI and SST was Staphylococcus aureus . - pubmed
A 46 - year - old man with acute low - back pain . - pubmed
The effects of aquatic trunk exercise on gait and muscle activity in stroke patients : a randomized controlled pilot study . - pubmed
[ Purpose ] The purpose of this study was to investigate the relationship between muscle activity and gait function following aquatic trunk exercise in hemiplegic stroke patients . - pubmed
[ Subjects and Methods ] This study 's participants included thirteen hemiplegic patients ( ten males and three females ) . - pubmed
DESIGN AND METHODS : Peripheral blood mononuclear cells from young TS patients ( n = 24 , 17.4 - 35.9 years ) and healthy controls ( n = 16 ) were stained with various Treg markers to characterize their phenotypes . - pubmed
Based on the presence of thyroid autoimmunity , patients were categorized into TS ( - ) ( n = 7 ) and TS ( + ) ( n = 17 ) . - pubmed
The FM patients were assessed using the following self - reported questionnaires : the Medical Outcomes Study Short - Form Health Survey , the Fibromyalgia Impact Questionnaire , the Brief Fatigue Inventory , the Beck Depression Inventory , the State - Trait Anxiety Inventory , the Self - Efficacy Scale , and the Social Support Scale . - pubmed
Malaria caused by Plasmodium vivax has recently shown resistance to chloroquine in some places . - pubmed
METHODS : Patients aged 13 - 65 years with confirmed mono - infection of P. - pubmed
METHODS AND RESULTS : The study comprised two equally sized cohorts of patients that had undergone retrospectively gated cardiac CT : patients who had MACE and/or all - cause death at follow - up and a matched ( age , sex , and risk factors ) event - free cohort . - pubmed
Of 166 patients , 31.3 % experienced MACE and 28.9 % died of any cause ( follow - up 22.9 + - 13.4 months ) . - pubmed
Strabismus in patients with cortical visual impairment : outcomes of surgery and observations of spontaneous resolution . - pubmed
PURPOSE : To investigate the rate of spontaneous resolution of strabismus in patients with cortical visual impairment ( CVI ) at a single center over a 10 - year period and to evaluate the success rate of strabismus surgery . - pubmed
METHODS : The medical records of patients with CVI and strabismus seen between October 2003 and October 2013 were reviewed retrospectively . - pubmed
Patients were classified into 4 outcome groups : ( 1 ) those who experienced spontaneous resolution of strabismus , ( 2 ) those with persistent strabismus who did not undergo surgery , ( 3 ) those who achieved postoperative alignment of & lt;=10(Delta ) ; and ( 4 ) those whose final postoperative alignment was 11(Delta)-25(Delta ) or & gt;25(Delta ) . - pubmed
Of these , 11 patients ( 16 % ) experienced spontaneous resolution of strabismus , 27 ( 38 % ) were observed without receiving surgery , and 32 ( 46 % ) underwent strabismus surgery . - pubmed
The patients who did not undergo surgery were significantly older at presentation ( 36 months vs 12 - 15 months ; P = 0.03 ) ; otherwise , there were no significant differences between groups in age at surgery or spontaneous resolution , type of strabismus , or underlying cause of CVI . - pubmed
CONCLUSIONS : In our study cohort , a minority of patients with CVI and strabismus ( 16 % ) experienced spontaneous resolution of strabismus . - pubmed
Strabismus surgery can be reasonably successful in properly selected patients with CVI and strabismus . - pubmed
These patients show considerable rates of resolution of their strabismus , either spontaneously or through surgery . - pubmed
The effect of aliskiren on the renal dysfunction following unilateral ureteral obstruction in the rat . - pubmed
Sarcopenia is closely associated with pancreatic exocrine insufficiency in patients with pancreatic disease . - pubmed
METHODS : Data were collected prospectively on 132 patients with pancreatic disease . - pubmed
CONCLUSIONS : Sarcopenia is independently associated with PEI in patients with pancreatic disease . - pubmed
Preparation of a cell line persistently infected with maedi / visna virus and production of viral antigens . - pubmed
Dermatophytosis is one of the most common human infections affecting both immunocompetent individuals and immunocompromised patients , in whom the disease is more aggressive and can reach deep tissues . - pubmed
MATERIALS AND METHODS : Human SH - SY5Y neuroblastoma cells were exposed to a 50 Hz , 100 muT MF with or without non - phototoxic level of blue light for 24 h. We also studied whether these treatments alter responses to menadione , an agent that induces mitochondrial superoxide ( O2 - ) production and DNA damage . - pubmed
The 1 - year dog toxicity study is no longer required by certain pesticide regulatory jurisdictions , including the United States and the European Union . - pubmed
: Human infection by orthopoxviruses is being reported with increasing frequency , attributed in part to the cessation of smallpox vaccination and concomitant waning of population - level immunity . - pubmed
Pseudomonas pachastrellae strain CCUG 46540 T ( KMM 330 T ) was isolated from a deep - sea sponge specimen collected in the Philippine Sea at a depth of 750 m. The draft genome has an estimated size of 4.0 Mb , exhibits a G+C content of 61.2 mol% , and is predicted to encode 3,592 proteins , including pathways for the degradation of aromatic compounds . - pubmed
Ciprofloxacin could be considered in the treatment of zoonotic Salmonellosis in humans . - pubmed
Therapeutic Mechanisms of Vernonia amygdalina Delile in the Treatment of Prostate Cancer . - pubmed
However , to the best of our knowledge , no previous reports have explored its therapeutic efficacy against human prostate cancer . - pubmed
The objective of the present study was to assess the anticancer activities of VAD methanolic extracts in the prevention and treatment of prostate cancer using human androgen - independent prostate cancer ( PC-3 ) cells as a test model . - pubmed
In Vivo Tracking of Human Adipose - derived Mesenchymal Stem Cells in a Rat Knee Osteoarthritis Model with Fluorescent Lipophilic Membrane Dye . - pubmed
In order to support the clinical application of human adipose - derived mesenchymal stem cell ( haMSC ) therapy for knee osteoarthritis ( KOA ) , we examined the efficacy of cell persistence and biodistribution of haMSCs in animal models . - pubmed
Subsequently , intra - articular injection of the labeled cells in rats with surgically induced KOA was monitored dynamically by an in vivo imaging system . - pubmed
This approach has been shown to be an efficient tracking method for haMSCs in a rat KOA model . - pubmed
MATERIALS AND METHODS : Members of the Endourologic Disease Group for Excellence research consortium prospectively enrolled patients with a renal stone burden ranging from 5 to 20 mm in this study . - pubmed
In addition to their anti - fatigue and anti - anoxia roles in traditional medicine , Rhodiola total extract and salidroside have also displayed medicinal properties as anti - cardiovascular diseases and anti - cancer agents . - pubmed
Objective : To investigate the correlation between Ishak inflammation score and the clinicopathological characteristics and recurrence of patients with hepatocellular carcinoma ( HCC ) after curative resection , and then set up a recurrence nomogram for HCC . - pubmed
Methods : A total of 326 patients with HCC after curative resection from January 2006 to December 2009 were studied retrospectively as training cohort and 110 HCC patients after surgery from January 2010 to December 2012 were used as validation cohort . - pubmed
Results : According to Ishak inflammation score , patients were divided into four subgroups : Grade I(1 - 4 scores ) , Grade II(5 - 8 scores ) , Grade III ( 9 - 12 scores ) and Grade IV(13 - 18 scores ) . - pubmed
Multivariate analysis showed that Ishak inflammation score(P=0.007 ) , HBV - DNA load(P<0.01 ) , tumor size(P=0.001 ) and microvascular invasion(P=0.001 ) were related with the recurrence of HCC patients . - pubmed
A total of 69 wounds in 64 patients were treated with an average wound size of 36.32cm2 . - pubmed
This study assessed the bronchodilator efficacy and safety of different doses of this formulation in patients with COPD to identify the optimal dose for further development . - pubmed
In this research , the complete genome sequence of strain SM30 T was determined , and its methylotrophy modules were characterized . - pubmed
CONCLUSION : Central line bundle programs were found to be effective in decreasing central line - associated bloodstream infection rates , improving patients ' quality of life by preventing ports removal due in pediatric cancer patients . - pubmed
This study aims to ( a ) estimate gender differences of the hepatotoxicity and toxicokinetics in rats after oral administration of emodin ( 60 and 150 mg / kg / d ) for a consecutive 28 days and ( b ) clarify relative mechanisms caused by glucuronidation and disposition . - pubmed
Hepatotoxicity was significantly higher in female rats than that in male rats , as evidenced by histopathological and biochemical tests . - pubmed
The new pathophysiological insights might be of relevance for the development of therapeutic strategies for caveolinopathy patients targeting improved protein folding capacity . - pubmed
Twelve patients with RS with different etiologies were selected and photogrammetric images were obtained prospectively in 3 patients with RS in whom mandibular growth in the first year of life was determined . - pubmed
METHOD : Acute liver failure was induced in mice using thioacetamide ( TAA ) ( 200 mg / kg , i.p ) once a day for two consecutive days . - pubmed
The sensor is reversible and the real - time sensing response is within 30 s. The results benefit the NO breath detection for patients with chronic inflammatory airway disease , such as asthma . - pubmed
A Randomized Open - Label Clinical Study Comparing the Efficacy , Safety , and Bioavailability of Calcium Lysinate with Calcium Carbonate and Calcium Citrate Malate in Osteopenia Patients . - pubmed
Methodology : A total of 24 osteopenia patients were randomly divided into three groups of eight subjects in each . - pubmed
Epizootic hemorrhagic disease ( EHD ) is a viral arthropod - borne disease affecting wild and domestic ruminants , caused by infection with epizootic hemorrhagic disease virus ( EHDV ) . - pubmed
Percutaneous biopsy was performed in 14 patients and FNH was diagnosed in nine patients , and hepatic adenoma , hepatocellular carcinoma , plasmacytoma , angiosarcoma , and atypical hepatocellular proliferation in one patient each . - pubmed
Brain radionecrosis was registered in 6 % of patients . - pubmed
MATERIALS AND METHODS : Retrospective analysis was conducted of 433 patients who underwent endovascular aneurysm repair ( EVAR ) of aortoiliac aneurysms with the use of Zenith stent grafts from 2007 to 2016 . - pubmed
Only 1 of 5 patients who underwent repeat intervention had a preoperative diagnosis of type IIIb endoleak , reflecting the difficulty in its diagnosis . - pubmed
Type IIIb endoleaks should always be considered in patients with sac expansion after EVAR . - pubmed
A 42 - year - old man presented paroxysmal sharp pain in the right side of the head . - pubmed
Therefore , this model is useful in evaluating mechanisms of cellular activation , peripheral tolerance and homeostatic immune imbalance involved in human SLE . - pubmed
A prospective , multicenter study of low - dose decitabine in adult patients with refractory immune thrombocytopenia . - pubmed
We conducted a prospective , multicenter study to evaluate the efficacy and safety of low - dose decitabine in adult patients with refractory immune thrombocytopenia . - pubmed
Adult patients who did not respond to , did not tolerate , or were unwilling to undergo splenectomy , with either a baseline platelet count less than 30 x 109 per L or the presence of bleeding symptoms and further need of ITP - specific treatments , were enrolled . - pubmed
In conclusion , low - dose decitabine is potentially effective and safe in the management of adults with refractory immune thrombocytopenia . - pubmed
The ( + -)- 2,3 - dihydro-4 ' , 8,8 '- trihydroxy -( 1,1 '- binaphthalen )- 4 ( 1H )- one showed selective inhibitory activity on tumor cells growth , preliminarily supporting the application of Juglans regia flowers to protect against cancers in a few Chinese folk areas . - pubmed
Non - steroidal anti - inflammatory drug ( NSAID ) therapy in patients with hypertension , cardiovascular , renal or gastrointestinal comorbidities : joint APAGE / APLAR / APSDE / APSH / APSN / PoA recommendations . - pubmed
RESULTS : Whenever possible , a NSAID should be avoided in patients with treatment - resistant hypertension , high risk of cardiovascular disease and severe chronic kidney disease ( CKD ) . - pubmed
The aim of this study is to investigate the timing of intubation of children with fulminant EV71 infection . - pubmed
We used rhombencephalitis grading to describe the neurological presentation of these patients . - pubmed
Mechanisms affecting exercise ventilatory inefficiency - airflow obstruction relationship in male patients with chronic obstructive pulmonary disease . - pubmed
METHODS : A total of 120 male patients with chronic obstructive pulmonary disease were enrolled . - pubmed
Effect of a Concurrent Cognitive Task , with Stabilizing Visual Information and Withdrawal , on Body Sway Adaptation of Parkinsonian 's Patients in an Off - Medication State : A Controlled Study . - pubmed
The aim of this study was to evaluate the role of the visual deprivation and a cognitive task on the static balance in earlier stage PD subjects . - pubmed
Methods : Fifteen off - medication state pwPD ( 9 women and 6 men ) , 67.7 + - 7.3 years old , diagnosed PD since 5.4 + - 3.4 years , only Hoehn and Yahr state 2 and fifteen young control adults ( 7 women and 8 men ) aged 24.9 + - 4.9 years , performed semi - tandem task under four randomized experimental conditions : eyes opened single - task , eyes closed single - task , eyes opened dual - task and eyes closed dual - task . - pubmed
Chronic airway allergy induces pro - inflammatory responses in the brain of wildtype mice but not 3xTgAD mice . - pubmed
Bronchoalveolar lavage fluid analysis confirmed eosinophilia in both genotypes , but the basal levels of eosinophils were lower in 3xTgAD mice . - pubmed
In summary , allergy induced predominantly anti - inflammatory effects in 3xTgAD mice , and pro - inflammatory effects in WT mice , thus being another potential factor to be considered when studying AD pathogenesis . - pubmed
AIMS : Intervertebral disc degeneration ( IVDD ) has been regarded as the main cause of low back pain , which affects 80 % of adults and still lack effective treatment . - pubmed
Total 166 Escherichia coli , Klebsiella pneumoniae and Klebsiella oxytoca were isolated from urine , wound swab , pus , sputum and blood samples of patients of Dhaka Medical College Hospital . - pubmed
Few animal models with neoplasia have been studied concerning the circulating tumor cells and it is likely that CTCs may have a predictive , diagnostic or therapeutic value . - pubmed
Herein , the authors review all studies in which human CTCs were transplanted into animals . - pubmed
Prevalence and Severity of Diabetic Retinopathy in Patients with Macular Telangiectasia type 2 . - pubmed
PURPOSE : To study the prevalence and severity of diabetic retinopathy ( DR ) in patients with macular telangiectasia type 2 ( MacTel2 ) . - pubmed
Diabetes mellitus type 2 was present in 50 patients ( 49 % ) and hypertension in 47 patients ( 46 % ) . - pubmed
Both eyes ( 1 % ) in one patient progressed to moderate DR . - pubmed
CONCLUSION : Although diabetes mellitus was highly prevalent among MacTel2 patients , there were no patients with severe or proliferative DR , or DME in our study . - pubmed
4 - -10 years after the injury 31 patients appeared at the check - inspection . - pubmed
Stereotypic and hypothermic effects of apomorphine and N - n - propylnorapomorphine in mice . - pubmed
Two dopaminergic agonists , apomorphine ( APO ) and N - n - propylnorapomorphine ( NPA ) were compared in mice for their ability to induce stereotypic cage - climbing and hypothermia . - pubmed
During the past eight years , we have treated three patients with olfactory neuroblastoma by a combination of extensive local surgery using the lateral rhinotomy approach with ethmoidectomy and medial partial maxillectomy , combined with either preoperative or postoperative irradiation therapy . - pubmed
Dermatophilosis ( streptothricosis ) in a buffalo calf ( Bubalus bubalis ) . - pubmed
Myocardial biopsies from two patients who had developed " stone heart " ( myocardial rigor mortis ; ischemic contracture of the left ventricle ) were studied by electron microscopy . - pubmed
Prolonged cardiac arrest and complete AV block during upright tilt test in young patients with syncope of unknown origin -- prognostic and therapeutic implications . - pubmed
The purpose of this study was to define the history and prognosis of 12 patients ( 8 males , 4 females ) with syncope of unknown origin ( 5 to 15 episodes ) , who developed prolonged asystole or complete AV block during the upright tilt test ( UTT ) . - pubmed
These patients were selected from a larger group of 92 cases with positive UTT out of a total of 136 subjects who were referred for recurrence of syncope . - pubmed
During follow - up ( mean , 17 + /- 5.4 months ) , four patients had recurrences but none experienced episodes of life - threatening syncope . - pubmed
These patients do not show an enhanced risk of sudden death , and drug therapy seems to improve their clinical course . - pubmed
Between 1987 and 1991 we performed a unilateral or bilateral frontoorbital advancement to correct trigono- or plagiocephaly in 10 children : Three - dimensional CT provides an exact basis for operation planning . - pubmed
From 1967 to 1991 we have diagnosed and treated 73 adrenal tumors in 63 patients : 12 pheochromocytomas , 24 adrenal cortical adenomas , 15 hyperplasias , 16 carcinomas , 3 myelolipomas , 2 cysts and 1 neuroblastoma . - pubmed
Five patients , 1 with localized secondary amyloidosis , are described . - pubmed
A sonicate antigen and two concentrations of a purified flagellum antigen of Borrelia burgdorferi were compared for serological diagnosis of Lyme borreliosis by an enzyme immunoassay ( EIA ) . - pubmed
It is concluded that purified Borrelia burgdorferi flagellum antigen is superior to a sonicate antigen , especially for serodiagnosis of the early stages of Lyme borreliosis . - pubmed
To evaluate the progression of idiopathic mitral valve prolapse ( MVP ) , a long time follow - up study ( mean 7.1 years ) was performed using echocardiography in 27 cases ( 11 males , 16 females , mean age : 50.4 years ) . - pubmed
Isolation of human T - lymphotropic virus type III from the tears of a patient with the acquired immunodeficiency syndrome . - pubmed
Human T - lymphotropic virus type III ( HTLV - III ) was isolated from the tears of 1 out of 7 patients with the acquired immunodeficiency syndrome ( AIDS ) or the AIDS - related complex . - pubmed
Thirteen patients were entered into an uncontrolled pilot study to investigate the response to , and toxicity of , a combination of cisplatinum ( 20 mg / m2 ) and bleomycin ( 6 mg / m2 ) infused daily for 5 days and repeated every 21 days up to a maximum of 4 cycles , in the treatment of squamous cell carcinoma of the bronchus . - pubmed
All patients have been followed to death . - pubmed
Lupus vulgaris caused by Mycobacterium bovis . - pubmed
The patients fell into the following diagnostic categories : postnecrotic cirrhosis 28 , primary biliary cirrhosis 20 , sclerosing cholangitis 19 , miscellaneous diseases 14 , carcinoma / neoplasia 12 and fulminant hepatitis 7 . - pubmed
Metabolic adjustments to dynamic hypoxic hypoxemia in feline brain tissue . - pubmed
The opportunity to study well - preserved biopsy tissue from a 38 - year - old man with the acute onset of dementia and AIDS encephalopathy prompted this report . - pubmed
Seventeen patients aged 47 - 67 years had 20 foci of disappearing breast calcifications . - pubmed
Efficacy of 5 - vinyl-1 - beta - D - arabinofuranosyluracil ( VaraU ) against herpes simplex virus type 2 strains in cell cultures and against experimental herpes encephalitis in mice : comparison with acyclovir and foscarnet . - pubmed
The sensitivity of different herpes simplex virus type 2 ( HSV-2 ) strains to inhibition by 5 - vinyl-1 - beta - D - arabinofuranosyluracil ( VaraU ) was evaluated in comparison to 9 -( 2 - hydroxyethoxymethyl ) guanine ( ACV ; acyclovir ) and trisodiumphosphonoformate ( Na3PFA ; foscarnet ) , using a plaque inhibition assay in primary rabbit testes ( PRT ) cells as well as in human embryonic lung fibroblast ( HELF ) cell cultures . - pubmed
Their in vivo efficacy was assessed in a mouse encephalitis model . - pubmed
Complications of combined radical hysterectomy - postoperative radiation therapy in women with early stage cervical cancer . - pubmed
[ Periodontal condition of 15 children with acute lymphatic leukemia or Hodgkin ' s lymphoma before and after induction therapy ] . - pubmed
In patients with combined aortoiliac and femoropopliteal occlusive disease , severe involvement of the deep femoral artery ( DFA ) has often been considered an indication for simultaneous aortofemoral and femorodistal bypass grafting . - pubmed
Effect of high calcium diet on magnesium , catecholamines , and blood pressure of stroke - prone spontaneously hypertensive rats . - pubmed
To test the effect of a high dietary calcium intake on blood pressure , we fed stroke - prone spontaneously hypertensive ( SHR - SP ) and Wistar - Kyoto rats ( WKY ) diets containing ( a ) 0.25 % Ca/0.08 % Mg , ( b ) 4.0 % Ca/0.02 % Mg , and ( c ) 4.0 % Ca/0.08 % mg , beginning at 6 weeks of age . - pubmed
SHR - SP and WKY rats receiving 4 % Ca with the lower Mg content had lower blood pressures , hypomagnesemia , and hypomagnesuria , and grew poorly . - pubmed
SHR - SP receiving 4 % Ca and the higher Mg diet had blood pressures no different from those of rats receiving the 0.25 % Ca diet , in spite of having lower body weights . - pubmed
[ Asthma associated with the handling of green coffee beans ] . - pubmed
Rat hepatocyte - mediated bacterial mutagenicity in relation to the carcinogenic potency of benz ( a ) anthracene , benzo ( a ) pyrene , and twenty - five methylated derivatives . - pubmed
[ Use of physical training in the rehabilitation of patients with post - infarct heart failure ] . - pubmed
The effect of exercise was examined in 15 postmyocardial - infarction patients showing clinical signs of heart failure ; 17 patients were taken as controls . - pubmed
In addition to a considerable increase in physical working capacity , the patients doing exercise showed more favorable hemodynamic response to stress that featured a greater stroke index , a smaller heart rate increment and a more significant fall in specific peripheral resistance . - pubmed
Ultracytochemical studies of lysosomal function in the macrophages of human leprosy -- I. - pubmed
A comparison between subjective audiometric and objective electrophysiological thresholds in patients with tinnitus . - pubmed
The second control group was composed of 8 patients suffering from sensorineural hearing loss without tinnitus . - pubmed
A patient with ulcerative colitis and primary sclerosis cholangitis confirmed by liver biopsy and endoscopic retrograde cholangiography presented with severely altered liver function tests . - pubmed
A 25 - year - old woman with long - standing hypergammaglobulinemic purpura developed distal renal tubular acidosis and a urine - concentrating defect . - pubmed
Specific antigen exclusion and non - specific facilitation of antigen entry across the gut in rats allergic to food proteins . - pubmed
Among the cervical cancer patients , the incidence of elevated TPA levels increased with stage of disease from 12 % in the preinvasive stage to 67 % in the advanced stage . - pubmed
Similarly , the TPA values were elevated in 35 % of the endometrial cancer patients . - pubmed
Among the patients with ovarian malignancies , serum TPA was elevated in the following order : LGM cases ( 33 % ) , Stage I ( 44 % ) , and advanced ( 88 % ) . - pubmed
However , serum TPA was elevated in 22 % of the patients with uterine myoma and in 12 % of those with ovarian benign tumors . - pubmed
The current observations demonstrate that the lack of tumor specificity of TPA limits its diagnostic value in gynecologic malignancies , but that serial measurements of this antigen appear to be useful for the evaluation of therapy and monitoring of patients . - pubmed
[ Leukocytotoxic antibodies in patients with different types of leukemias ] . - pubmed
[ Study using a new ultrafiltration technic of Bence Jones protein in patients with paraproteinemia ] . - pubmed
Letter : Hamsters as sentinels for leishmaniasis and arboviruses . - pubmed
Effect of rubella vaccine on transplacental rubella virus infection in rabbits . - pubmed
Survival of children with severe chronic uremia . - pubmed
Antigenic variation in a strain of Trypanosoma congolense transmitted by Glossina morsitans . - pubmed
[ A contribution to the clinical picture of the mesenteric form of human Pasteurella pseudotuberculosis infection ] . - pubmed
Light - induced susceptibility of Phaseolus vulgaris L. to tobacco mosaic virus infection . - pubmed
[ Study of the receptor sensitivity to glucagon in patients with bronchial asthma ] . - pubmed
Hypercalcaemia occurring after ten weeks of immobilisation was observed in four adult patients all of whom had had prior renal failure sufficient to require renal dialysis . - pubmed
Abuse of alcohol and tobacco , mineral deficiencies , malnutrition , the use of sorghum in the daily diet , and reverse smoking by females , are factors believed to be responsible for high rates in the past . - pubmed
This resulted in a reduced mineral concentration in the fractures of treated rats compared to controls in the last part of the experiment . - pubmed
We describe three patients with HG who also had Graves ' disease , and , in addition , one of these patients had alopecia totalis and ulcerative colitis . - pubmed
Effect of vitamin B2 on tumorigenesis of 3 - methylcholanthrene in the mouse skin . - pubmed
Local administration of riboflavin 2 ' , 3 ' , 4 ' , 5 '- tetrabutyrate ( B2 - But4 ) suppressed the induction of skin tumors in mice by 3 - methylcholanthrene . - pubmed
Aspirin effect on cataract formation in patients with rheumatoid arthritis alone or combined with diabetes . - pubmed
The prevalence of cataracts is significantly lower in patients with rheumatoid arthritis receiving aspirin ( mean of 2,700 mgs daily for an average of 10.4 years ) as compared to the matched population not receiving aspirin . - pubmed
A study was made of the incidence of postoperative endocarditis and of septicaemia in early convalescence in 814 consecutive patients undergoing open - heart surgery . - pubmed
Preclinical studies in the laboratory and in animals now suggest the feasibility of investigating such an agent in the targeted therapy of patients with human breast cancer . - pubmed
In rats , physical correlates have been characterized as intense hyperactivity together with jumping , ptosis , teeth chattering , wet dog shakes , and diarrhea . - pubmed
METHOD : A consecutive series of 113 consenting inpatients meeting DSM - III - R criteria for schizophrenia ( 45 females , 68 males ) were assessed using reliable measures of depression and negative symptoms . - pubmed
Several experimental conditions were used in this study to evaluate the in vitro effects of 15 - deoxyspergualin on the function of T lymphocytes , B lymphocytes and monocytes from healthy subjects and patients suffering from systemic lupus erythematosus . - pubmed
The subjects were 88 women aged 50 - 59 years ( including 32 with fracture ) , 95 women aged 60 - 69 years ( including 54 with fracture ) , and 34 women aged 70 - 79 years ( including 18 with fracture ) . - pubmed
Previous studies of regional differences in myocardial deformation between the anterior and posterior walls of the canine left ventricle were based on strain , which is not an absolute measure of deformation . - pubmed
Raising at thermoneutrality prevents obesity and hyperphagia in BAT - ablated transgenic mice . - pubmed
A deficit in energy expenditure for brown adipose tissue ( BAT ) thermogenesis in these mice is presumed to contribute to the development of obesity . - pubmed
The objective of the present study was to obviate any deficit in BAT thermogenesis by raising transgenic and control mice at thermoneutrality ( 35 degrees C ) , where both would have equally inactive BAT , to see whether this would prevent the obesity and the hyperphagia . - pubmed
As seen before , transgenic mice raised at 24 degrees C had excess weight gain by 6 wk of age and by 8 wk had doubled carcass fat , an obesity characterized by increased white adipocyte size with no increase in number of adipocytes . - pubmed
UCP - DTA mice thus differ from genetically obese mice ( ob / ob , db / db ) for which raising at thermoneutrality is known not to prevent either the obesity or the hyperphagia . - pubmed
The sequence revealed that this isolate was a type-1 ADV strain , supporting that the currently used typing of ADV viruses does not correlate with virulence or pathogenicity . - pubmed
ADV - SL3 had a very high overall homology of 99.5 % to the prototype strain ADV - G at the DNA level . - pubmed
Comparative sequence analyses with various ADV isolates of known virulence did not reveal a consensus sequence that could obviously be responsible for the apparently unique biological properties of this virus strain . - pubmed
In a double - blind , parallel - group study , we examined the effect of short - term treatment with inhaled fluticasone propionate ( FP ) in a group of 20 nonsmoking asthmatic patients who required only beta2 - agonists to control their symptoms . - pubmed
When sand rats are transferred from their natural desert environment and placed on a laboratory chow diet , they become overweight , develop hypertriglyceridaemia , hypercholesterolaemia , become insulin resistant , and ultimately diabetic . - pubmed
In the present study glucose intolerant animals , with very mild if any hyperglycaemia were used . - pubmed
These data confirm in another animal model the therapeutic benefits of S15261 in insulin resistant states . - pubmed
In conclusion , the clinical presentation of acute hepatitis C is generally mild in chronic haemodialysis patients , but spontaneous resolution is infrequent . - pubmed
Inhaled anticholinergics are particularly useful in patients with COPD and in the future long - acting drugs , such as tiotropium bromide , will be available . - pubmed
Inhaled glucocorticoids are the most effective therapy in controlling chronic asthma symptoms , and systemic effects are not a problem in the vast majority of patients . - pubmed
METHODS : An 11 - year - old boy had an 8 - year history of diffuse conjunctival papillomas , treated previously with standard measures of excisional biopsy and cryotherapy . - pubmed
gene transfer at day 15 of gestation in a murine model of hemophilia A. - pubmed
METHODS : The patients selected had unequivocal evidence of H. - pubmed
B - lymphotropic viruses in a novel tropical splenic lymphoma . - pubmed
However , lymphoma patients had markedly raised EBV antibody levels without a concomitant increase in the rate of detection of viral genomes in the peripheral blood . - pubmed
Photoirradiation of mice at various times after injection indicated there was no correlation between photosensitivity and immunosuppression . - pubmed
Infusion of methylene blue in human septic shock : a pilot , randomized , controlled study . - pubmed
PATIENTS : Twenty patients with septic shock diagnosed & lt;24 hrs before randomization . - pubmed
CONCLUSIONS : In human septic shock , continuously infused MB counteracts myocardial depression , maintains oxygen transport , and reduces concurrent adrenergic support . - pubmed
Our aim was to assess the contribution of hydroxyl radicals to early neuropathic changes by examining the effects of treatment with the specific scavenger , dimethylthiourea , on nerve function and neural tissue blood flow in diabetic rats . - pubmed
CONCLUSION / INTERPRETATION : Hydroxyl radicals seem to make a major contribution to neuropathy and vasculopathy in diabetic rats . - pubmed
The data suggest that the development of potent hydroxyl radical scavengers suitable for use in man could markedly enhance the potential therapeutic value of an antioxidant approach to the treatment of diabetic neuropathy and vascular disease . - pubmed
A case of SCC of the pleura in a 66 - year - old man with pre - existent asbestos - related pleural plaques is presented . - pubmed
This is the first case of pleural SCC in a patient with asbestos - induced pleural disease and the third reported case of a pleural SCC . - pubmed
The SCC developed in an area with pre - existent pleural thickening , underlining the need for careful analysis of alterations in the manifestation of pleural disease in patients with asbestos exposition . - pubmed
METHODS : All 40 skeletal Class III malocclusion patients we analyzed were from joint clinic of our hospital . - pubmed
After presurgical orthodontic treatment , most of the patients could be treated by one piece surgery , which could simplify the surgical procedure and reduce the relapse rate of surgery . - pubmed
Human defensive behaviors to threat scenarios show parallels to fear- and anxiety - related defense patterns of non - human mammals . - pubmed
REE , though slightly elevated compared to healthy children ( baseline 106%+/-8 % predicted ) , remained stable throughout the study and at a level which may be expected for children with minimal lung disease . - pubmed
CONCLUSIONS : In summary , these pilot data from younger children with milder CF - related lung disease do not confirm anecdotal reports of improved rate of weight gain , caloric intake or decreases in the elevated REE . - pubmed
Defective calcium ( Ca ( 2 + ) ) signaling , manifest as a loss of excitation - contraction ( EC ) coupling gain in cardiac muscle , likely plays an important role in the pathophysiology of human heart failure . - pubmed
Molecular pathogenesis of human hepatocellular carcinoma . - pubmed
BACKGROUND : There is no standard treatment for patients with infected abdominal aortic aneurysm ( AAA ) . - pubmed
To determine the basis for selection of a surgical method , we reviewed our experiences with all patients who underwent surgery for infected infrarenal AAA . - pubmed
METHODS : Between 1993 and 2000 , 6 patients with infected infrarenal AAA underwent surgery . - pubmed
Extra - anatomic bypass grafting was performed in 2 of 3 patients with infection extending into the retroperitoneum . - pubmed
In situ grafting was performed in 3 patients with localized infection and in 1 patient with extended infection . - pubmed
RESULTS : Severe peritonitis occurred in 2 patients with extended infection in the early postoperative phase . - pubmed
One patient , who had undergone in situ grafting , died of sepsis . - pubmed
For a patient with extended infection , postoperative continuous irrigation with ESAAS appears to be effective in eradicating retroperitoneal infection . - pubmed
Effectiveness of the anger - control program in reducing anger expression in patients with schizophrenia . - pubmed
The purpose of this study was to evaluate the anger control program in reducing anger expression in patients with schizophrenia . - pubmed
The program was found to reduce anger expression in patients with schizophrenia effectively and to increase their anger control ability . - pubmed
We have determined that the striatal dopaminergic neurotoxicity observed in the mouse is linked in some fashion to both body and environmental temperature . - pubmed
An increase in neurotoxicity was also apparent in mice kept at an elevated temperature for only 5 or 9 h , but keeping animals at 27 degrees C for 24 or 72 h was the most effective in increasing the neurotoxicity of d - METH . - pubmed
MATERIAL : Sixty - five adults ( 52 females , 13 males ) with a history of or still active JCA were assessed an average of 26.7 years after disease onset . - pubmed
RESULTS : Evidence of ocular complications was found in 13 subjects ( 20 % ): 10 had had recurrent iritis , two band keratopathy , and one diplopia due to rheumatoid eye muscle involvement . - pubmed
Binocularly , all but one patient scored at least 6/9 as best corrected visual acuity ; one , however , had severe glaucoma - impaired visual fields . - pubmed
CONCLUSION : Ophthalmic complications were recorded in 20 % of the study group , primarily in ANA positive patients with pauciarticular onset JCA . - pubmed
In addition to the two patients with severely affected bilateral visual status ( 3 % ) , one of the 65 patients had acquired unilateral blindness . - pubmed
HYPOTHESIS : Patients who undergo laparoscopic refundoplication for postoperative intrathoracic wrap herniation using a circular polypropylene mesh for hiatal closure have a good to excellent functional outcome , during a complete follow - up of 1 year . - pubmed
PATIENTS : Twenty - four patients undergoing laparoscopic refundoplication for persistent or recurrent symptoms of gastroesophageal reflux disease as a result of postoperative intrathoracic wrap migration . - pubmed
In a prospective study on 57 patients with venous ulceration we found significant lower recurrence rates after mesh graft tissue transfer and radical surgical debridement . - pubmed
[ Heat tolerance of patients with cardiac and vascular diseases under electric light baths ] . - pubmed
The public health significance of staphylococcic infection in cattle . - pubmed
[ Ammonia levels of human blood following injection of protein hydrolysates in relation to hepatic coma ] . - pubmed
OBJECTIVE : The goal of this study was to evaluate the clinical implications of integrating human papillomavirus ( HPV ) testing into a long - term follow - up and management protocol for women postconization for high - grade cervical intraepithelial neoplasia ( CIN2 - 3 ) . - pubmed
Eleven ( 37.9 % ) had high - grade cervical intraepithelial neoplasia or high - load HPV results and were further treated by reconization / hysterectomy . - pubmed
The respective positive predictive values of high - load HPV and low - grade squamous intraepithelial lesions were 100 and 60 % for any CIN and 90 and 15 % for CIN2 - 3 . - pubmed
OBJECTIVE : The purpose of this study was to determine which histologic features could enable one to distinguish oral condyloma , as defined by the detection of human papillomavirus ( HPV ) DNA through in situ hybridization , from its mimics . - pubmed
STUDY DESIGN : Thirty - two paraffin - embedded specimens from 28 patients that were clinically suggestive of oral condyloma were analyzed histologically and through in situ hybridization with a consensus HPV probe . - pubmed
The histologic features significantly associated with HPV detection were nonuniform perinuclear halos , often in association with epithelial crevices ( P = .02 ) , and papillomatosis ( P = .02 ) . - pubmed
Each of the 17 patients who were HPV - positive had either HPV-6 or HPV-11 , a finding that is similar to those for condyloma involving the penis and vulva / vagina . - pubmed
Bovine herpesvirus 4 ( BoHV-4 ) is a gammaherpesvirus with no clear disease association , it establishes persistent infections in its natural host , the bovine , and in an experimental host , the rabbit . - pubmed
METHODS AND MATERIALS : The study was performed in transplanted radiation - induced fibrosarcoma tumors ( RIF-1 ) in 18 female C3H / HEJ mice , which had two lithium phthalocyanine ( LiPc ) deposits implanted in the tumor when the tumors reached about 200 - 600 mm(3 ) . - pubmed
Clinicopathologic characteristics of 143 patients with synchronous bilateral invasive breast carcinomas treated in a single institution . - pubmed
METHODS : Between April 1997 and February 2003 , 143 consecutive patients with SBIBC were treated at the European Institute of Oncology ( Milan , Italy ) . - pubmed
During the same time period , 6218 patients with unilateral invasive breast carcinoma ( UIBC ) were analyzed in the same manner for comparison with the patients with SBIBC . - pubmed
A tetraploid hybrid F2 population originating from a cross between a Salix dasyclados clone ( SW901290 ) and a Salix viminalis clone ( ' Jorunn ' ) was used in the study . - pubmed
In two patients conversion was necessary , one due to bleeding of an earlier clipped lumbar artery after completion of the anastomosis , the other because of difficulties with the laparoscopic exposure of the aorta . - pubmed
METHODS : In a retrospective study we surveyed 98 hospitalized malnourished children ( ZW<--2 ) with no chronic disease . - pubmed
Diarrhea and/or pneumonia were diagnosed at admission in 81.6 % of the children . - pubmed
To identify the diagnostic pitfalls as well as the value of immunohistochemical studies in making a pathologic evaluation of a pediatric intestinal pseudo - obstruction ( IPO ) , this study reassessed the pathology of 87 surgically resected intestines from 80 patients under the impression of IPO and 10 normal controls using immunohistochemical studies . - pubmed
The final group was composed of eight men and seven women , each having one to seven chronic , stable psoriatic plaques . - pubmed
In a few patients , blistering and burning sensation after some sessions were noted . - pubmed
We also suggest animal models and human studies to test our hypothesis , the results of which may offer novel approaches in the prevention of insulin resistance and atherosclerosis . - pubmed
METHODS : For this study , 28 patients with early gastric cancers in the lower half of the stomach were randomly assigned to either LADG ( n = 4 ) or ODG ( n = 14 ) . - pubmed
Gliomas represent the most frequent type of human brain tumor , and their strong invasiveness is a significant clinical problem . - pubmed
Patients were followed up for a minimum of one year or until death . - pubmed
Variability , regularity , and complexity of time series generated by schizophrenic patients and control subjects . - pubmed
We analyzed time series generated by 20 schizophrenic patients and 20 sex- and age - matched control subjects using three nonlinear methods of time series analysis as test statistics : central tendency measure ( CTM ) from the scatter plots of first differences of data , approximate entropy ( ApEn ) , and Lempel - Ziv ( LZ ) complexity . - pubmed
RESULTS : Eighteen of 51 patients ( 35 % ) developed HAMA following RIT ( range of ultimate maximum titers , 6.6 - 1,802 microg / ml ) . - pubmed
Patients who undergo surgery in confirmed T3N1 stage are faced with 5 year survival period in 8%-10 % of the cases , emphasizing the fact that these tumors are operable , but rarely curable by surgery itself . - pubmed
Neo adjuvant therapy use is increasing for the patients in stages IIB and IIC ( local progression of the tumor ) , aiming to decrease the size of the primary cancer prior to surgery thus increasing the rate of long term survival . - pubmed
Our experiences brought out in this study correlate with the foreign results thus aging stressing the fact that the exact staging of the tumor is the basics for the treatment as well as the right choice of the patients for surgery treatment , and those who need neo adjuvant therapy . - pubmed
Strains belonging to three novel yeast species , Candida heliconiae ( four isolates ) , Candida picinguabensis ( three isolates ) and Candida saopaulonensis ( two isolates ) , were recovered in the year 2000 from water of flower bracts of Heliconia velloziana L. Emigd . - pubmed
The type strains are C. - pubmed
METHODS : Over a 24 - month period , 41 patients , including 20 with hepatocellular cancer ( HCC ) , 14 with liver metastases from colorectal tumors and 7 with metastases from other tumors , underwent RFA in our institution . - pubmed
Among 20 patients with HCC , 16 had complete tumor ablation and one had failure of localization . - pubmed
All patients with liver metastases had successful tumor ablation . - pubmed
Two patients had hemoperitoneum and one experienced skin burn . - pubmed
During a median follow up of 16 months , five patients with HCC and two with colorectal metastases died . - pubmed
One patient had tumor recurrence at the ablation site and two developed fresh solitary metastatic lesions ; all three are disease - free after repeat ablation treatment . - pubmed
We examined whether the two most strongly associated variants ( rs12255372 and rs7903146 ) predict the progression to diabetes in persons with impaired glucose tolerance who were enrolled in the Diabetes Prevention Program , in which lifestyle intervention or treatment with metformin was compared with placebo . - pubmed
Stress - induced visceral hyperalgesia was abolished when alosetron was injected intrathecally ( P<0.05 ) in intact rats or subcutaneously ( 0.3 mg / kg ) in capsaicin - pretreated animals ( P<0.05 ) . - pubmed
For prevention of lethal arrhythmias , patients at risk receive implantable cardioverter - defibrillators , which use high - frequency antitachycardia pacing ( ATP ) to convert tachycardias to a normal rhythm . - pubmed
CLINICAL PRESENTATION : An 18 - year - old girl presented with long - standing intermittent retro - orbital pain and oculomotor paresis . - pubmed
Postoperatively , the patient became pain - free , and her oculomotor function partially recovered . - pubmed
The study of human skin irritation of a novel herbal skin care product and ingredients by human single closed patch testing . - pubmed
OBJECTIVE : Evaluate the irritation potential of GPO products on human skin using the single application closed patch test under occlusion . - pubmed
The large - cell small - acinar thyroid tumour of Langhans and the incidence of related cell groups in the human thyroid . - pubmed
We report the case of a patient who received DMSO - cryopreserved APBSC after myeloablative chemotherapy for a relapsing lymphoma . - pubmed
The patient developed a rare reaction during the infusion manifesting as transient global amnesia . - pubmed
The present pilot study compared the ability of a conventional patient complaint - driven approach to that of nucleic - acid amplification testing ( NAAT ) of urine to identify those individuals among an adult , urban , Emergency Department ( ED ) population infected with Chlamydia trachomatis ( CT ) , Neisseria gonorrhoeae ( NG ) , and Trichomonas vaginalis ( TV ) . - pubmed
Effect of polymer coating on faecal recovery of ingested 5 - amino salicylic acid in patients with ulcerative colitis . - pubmed
To do so , three common times of virus inoculation were examined ( 0.5 , 4 , and 12 h ) along with two routes of inoculation ( immersion and spot inoculation ) , and then two recovery methods were compared ( physical removal and chemical extraction / blending ) utilizing three different recovery eluents ( 2 % media , beef extract , and phosphate - buffered saline ) . - pubmed
In general , media containing 2 % fetal bovine serum had more efficient recovery of the three viruses , and spot inoculation was observed to be more efficient than inoculation by immersion . - pubmed
RESULTS : The liver cancer cell line HepG2 was treated with essential oils from Rosmarinus officinalis at various concentrations for different duration . - pubmed
FQ is able to overcome the CQ resistance problem , an important limit to the control of Plasmodium falciparum , the principal causative agent of malaria . - pubmed
RESULTS : Triple - negative tumors occurred in 117 ( 18.9 % ) of the 620 patients , most often in association with invasive ductal carcinomas . - pubmed
Patients with triple - negative tumors were younger than those with other receptor types , 44.5 % and 26.7 % , respectively , being diagnosed at age & lt;50 years ( P = 0.0004 ) . - pubmed
[ Prevention and therapy of critical ischemia in hemodialyzed patients ] . - pubmed
The cardiovascular disease is largely increased in chronic renal failure and the patients have a 10 - 20 times higher mortality respect normal population . - pubmed
In our experience appears that dialysed patients present high total mortality and re - vascolarization ( particularly for peripheral occlusive disease ) gives less guarantee of success . - pubmed
MATERIALS AND METHODS : We retrospectively analyzed 118 consecutive case records of patients admitted with acute pancreatitis . - pubmed
Forty - four patients had a severe acute necrotizing pancreatitis and only those were analyzed . - pubmed
In this article , I argue that prevention of cardiac dysfunction in patients with lower grades of MDS may not be the major benefit of iron chelation therapy , and present evidence suggesting a potential benefit of iron chelation on 3 other outcomes , namely ( 1 ) lowering infection risk , ( 2 ) improving the outcome of allogeneic hematopoietic stem cell transplantation , and ( 3 ) delaying leukemic transformation . - pubmed
These outcomes have particular relevance for patients with higher grades of MDS and should be evaluated in future prospective clinical trials that include patients with all grades of MDS to fully evaluate the benefit of iron chelation therapy . - pubmed
We have adduced strong evidence in favor of identifying the virus of Mexican typhus fever with the Rickettsiae , or Mooser bodies , observed in the tunica lesions of Mexican typhus guinea pigs . - pubmed
PARTICIPANTS : One hundred twenty - two patients ( 126 eyes ) with corneal diseases that were deemed ineligible to receive donor corneal transplants . - pubmed
MAIN OUTCOME MEASURES : The medical records of the patients were reviewed to assess intraoperative and postoperative complications , uncorrected and best - corrected visual acuity , as well as the degree of refractive error at various time points . - pubmed
The mean spherical refractive error was -0.57 diopters ( D ) and mean astigmatism was 0.10 D. Cumulatively , 7.1 % patients achieved their best - corrected vision at 1 day , 24.6 % at 1 week , and 70.6 % at 3 months . - pubmed
The patients who achieved their best - corrected visual acuity after the first 3 - month period most often were the ones who required multiple surgeries owing to preexisting or postoperative complications . - pubmed
CASE REPORT : We report a case of a 52 - year - old woman , who presented with progressive hearing loss and fullness in the left ear for 3 months . - pubmed
Follow - up of the patient is essential in order to detect possible recurrence . - pubmed
Gingival enlargement in children administered cyclosporine after liver transplantation . - pubmed
This study investigates the effects of cyclosporine on the gingival tissues of liver - transplant pediatric patients , determines the prevalence and severity of gingival overgrowth , and analyzes the relationship between gingival enlargement and possible risk factors . - pubmed
METHODS : Twenty - five children aged & lt;4 years old ( 15 males and 10 females ) with end - stage liver disease , and awaiting liver transplantation were selected for this study . - pubmed
RESULTS : The results show that the cyclosporine - induced gingival enlargement of these children is not statistically associated with their age , gender , gingival inflammation , or serum level of cyclosporine ( P & gt;0.05 ) . - pubmed
CONCLUSIONS : Children administered cyclosporine after liver transplantation show that gingival enlargement is statistically more related to the plaque index than other factors such as age , gender , gingival inflammation , or the serum level of cyclosporine , which suggests that plaque control plays an important role in eliminating gingival enlargement in children who have undergone liver transplantation . - pubmed
OBJECTIVE : Percutaneous radiofrequency ablation ( RFA ) has shown efficacy in patients with recurrent hepatocellular carcinoma , but has not been well documented in patients with recurrent intrahepatic cholangiocarcinoma ( ICC ) . - pubmed
CONCLUSION : RFA is safe and provides successful local tumor control in patients with recurrent ICC after curative resection . - pubmed
Skin vaccination against cervical cancer associated human papillomavirus with a novel micro - projection array in a mouse model . - pubmed
Here we investigate a novel dry - coated densely - packed micro - projection array skin patch ( Nanopatch ) as an alternate delivery system to intramuscular injection for delivering an alum adjuvanted human papillomavirus ( HPV ) vaccine ( Gardasil ) commonly used as a prophylactic vaccine against cervical cancer . - pubmed
Myocardial parvovirus B19 persistence : lack of association with clinicopathologic phenotype in adults with heart failure . - pubmed
Our studies do not support a causative role for parvovirus B19 persistence in HF and , therefore , advocate against the use of antiviral therapy for these patients . - pubmed
Influence of atorvastatin on the pharmacokinetics and pharmacodynamics of glyburide in normal and diabetic rats . - pubmed
We have studied the effects of atorvastatin on the pharmacodynamics and pharmacokinetics of glyburide in experimental diabetic rats . - pubmed
was given to alloxan - induced diabetic rats for 7 consecutive days followed by glyburide ( 10mg / kg p.o . ) - pubmed
[ The impact of tobacco smoking on oxidative stress parameters in the blood of normal glucose tolerance persons and subjects with pre - diabetes , separately ] . - pubmed
MATERIAL AND METHODS : Caucasian females and males aged 35 - 64 , with no acute or severe chronic disorder , taking no medication , special diet nor supplementation were enrolled to the study . - pubmed
After receiving oral glucose tolerance test results , newly diagnosed type 2 diabetic subjects were excluded , and normal glucose tolerance ( NGT ) and pre - diabetic ( PreDM ) persons underwent further investigation . - pubmed
METHODS : A retrospective analysis of 52 consecutive patients treated for infrarenal occlusive aortic disease with primary stenting between January 2002 and November 2009 was performed . - pubmed
Early surgical revision was necessary for aortic rupture in 1 patient . - pubmed
The rats were exposed to a hypoxia condition of 10 % for 0 , 2 , 12 , and 24 hr at sea level . - pubmed
Some human embryonic stem cell lines have shown genomic instabilities over long - term culture . - pubmed
Although the use of peritoneovenous shunts for intractable ascites has been reported previously , our cases differ in both technique and patient size . - pubmed
Our first patient is an ex-28 - week premature , 1.4 - kg infant with intractable ascites for which a peritoneal drain was initially placed . - pubmed
The second patient was 5 months old , 2.8 kg , with a course complicated by necrotizing enterocolitis , prolonged total parenteral nutrition , and progressive liver failure and underwent the same procedure . - pubmed
Both patients had dramatic responses to the shunting postoperatively , with clinical , radiographic , and laboratory evidence of resolution of the ascites . - pubmed
The first patient had the shunt removed at 6 months of age and continues to do well , whereas our second patient had no recurrence of the ascites , but died about 1 year later from cardiopulmonary complications . - pubmed
STUDY DESIGN & amp ; SETTING : Cross - sectional study of ambulatory individuals with prevalent cardiovascular disease . - pubmed
the area of breast including the primary tumor bed and the surrounding tissue ) using 3D - CRT with patients in prone position . - pubmed
Poor sleep quality is associated with depressive symptoms in patients with heart disease . - pubmed
BACKGROUND : Depression in cardiac patients has gained importance due to increased mortality . - pubmed
PURPOSE : This cross - sectional study aims to examine sleep disturbances and depressive symptoms in consecutively admitted cardiac patients and depressed patients . - pubmed
METHODS : Two hundred four inpatients ( 113 male , 91 female ) were examined : 94 cardiac inpatients ( mean age 49.3 + - 14.3 years ) with different heart diseases and 110 psychiatric inpatients ( mean age 41.6 + - 13.0 years ) with depressive disorders ( DP ) . - pubmed
A depressive episode according to International Classification of Diseases ( ICD)-10 was also diagnosed in 14 of the cardiac patients ( DCP ) . - pubmed
This study investigated the posterior movement of the spinal cord after posterior decompression surgery and evaluated factors affecting postoperative functional recovery in patients with cervical spondylotic myelopathy ( CSM ) . - pubmed
MATERIAL AND METHODS : Endomyocardial biopsy was performed in 195 IDCM patients , and five to six specimens were collected from the left ventricle . - pubmed
Autonomic ganglionated plexi : characterization and effect of epicardial microwave ablation in a canine model of vagally induced acute atrial fibrillation . - pubmed
METHODS : : 8 Mongrel dogs ( 25 - 31 kg ) , underwent cervical vagal trunk stimulation to produce AV nodal block and sustained AF . - pubmed
RESULTS : : Baseline cervical vagal stimulation produced AV block and AF in all the animals . - pubmed
We aimed to evaluate the surgical indication , especially for the patients with concomitant multiple liver metastases or extreme local invasions . - pubmed
METHODOLOGY : The overall survival ( OS ) and the disease free survival ( DFS ) were statistically analyzed for twenty one patients with PNETs who underwent surgical intervention in our institute . - pubmed
CONCLUSIONS : Appropriate radical operation with multi - disciplinary treatments could contribute to the patients ' survival in the treatment strategy of PNETs . - pubmed
[ Bariatric surgery in a patient with adipositas permagna and uncontrolled insulin resistance ] . - pubmed
HISTORY AND ADMISSION FINDINGS : A 58 - year - old patient had a 21 years history of diabetes mellitus and multiple diabetic complications . - pubmed
The treatment improved the patient 's quality of life , optimized metabolic control and resulted last but not least in lower costs for the diabetes treatment . - pubmed
[ Perineal urethrostomy plus secondary urethroplasty for ultralong urethral stricture : clinical outcomes and influence on the patient 's quality of life ] . - pubmed
OBJECTIVE : To investigate the outcomes of perineal urethrostomy plus secondary urethroplasty for ultralong urethral stricture and assess its influence on the patient 's quality of life . - pubmed
The mean age of the patients was 40 years , and the average length of stricture was 6.5 cm . - pubmed
We evaluated the patients'quality of life by questionnaire investigation and the clinical outcomes based on IPSS , Qmax , the necessity of urethral dilation and satisfaction of the patients . - pubmed
CONCLUSION : Perineal urethrostomy plus secondary urethroplasty is safe and effective for ultralong urethral stricture , and affects very little the patient 's quality of life . - pubmed
Neurodevelopmental outcomes in children with Angelman syndrome after 1 year of behavioural intervention . - pubmed
OBJECTIVE : To examine the impact of teaching approaches based on the principles of applied behaviour analysis ( ABA ) on neurodevelopmental outcomes in children with Angelman syndrome ( AS ) . - pubmed
The intervention group consisted of four children with AS aged 3.1 - 9.2 years . - pubmed
Controls were other children with AS who were individually matched on the basis of chronological age , gender and molecular sub - type . - pubmed
CONCLUSION : ABA - based intervention improved aspects of neurodevelopment for some children with AS and warrants further study . - pubmed
We aimed to determine whether the use of a 3 - step critical pathway is safe and effective in reducing duration of intravenous antibiotic therapy and length of stay in hospitalized patients with CAP . - pubmed
Secondary end points were the duration of intravenous antibiotic therapy , adverse drug reactions , need for readmission , overall case - fatality rate , and patients ' satisfaction . - pubmed
More patients assigned to usual care experienced adverse drug reactions ( 4.5 % vs 15.9 % [ difference , -11.4 percentage points ; 95 % CI , -17.2 to -5.6 percentage points ; P & lt ; .001 ] ) . - pubmed
CONCLUSIONS : The use of a 3 - step critical pathway was safe and effective in reducing the duration of intravenous antibiotic therapy and LOS for CAP and did not adversely affect patient outcomes . - pubmed
Such a strategy will help optimize the process of care of hospitalized patients with CAP , and hospital costs would be reduced . - pubmed
Evaluation of the hepatoprotective Effects of Lantadene A , a pentacyclic triterpenoid of Lantana plants against acetaminophen - induced liver damage . - pubmed
The aim of the present study was to evaluate the hepatoprotective activity of lantadene A against acetaminophen - induced liver toxicity in mice was studied . - pubmed
RESULTS : Among the 93 PCG patients whose sex was recorded , 57 were male ( 61.3 % ) and 36 were female ( 38.7 % ) ( P=0.03 ) . - pubmed
Compared with wild - type mice , the miR21 deletion in ECs resulted in structural and functional remodeling of aorta significantly , such as diastolic pressure dropping , maximal tension depression , endothelium - dependent relaxation impairment , an increase of opening angles and wall - thickness / inner diameter ratio , and compliance decrease , in the miR21 endothelial - specific knockout mice . - pubmed
Modeling hepatic osteodystrophy in Abcb4 deficient mice . - pubmed
Hepatic osteodystrophy ( HOD ) denotes the alterations in bone morphology and metabolism frequently observed in patients with chronic liver diseases , in particular in case of cholestatic conditions . - pubmed
METHODS : CNAs in tumor DNA samples from 125 patients in the discovery cohort who underwent prostatectomy were assayed with high - resolution Affymetrix 6.0 single - nucleotide polymorphism microarrays and then analyzed using the Genomic Identification of Significant Targets in Cancer ( GISTIC ) algorithm . - pubmed
Based on modern cell , animal , and human studies , piperine has been found to have immunomodulatory , anti - oxidant , anti - asthmatic , anti - carcinogenic , anti - inflammatory , anti - ulcer , and anti - amoebic properties . - pubmed
Although neuronal migration disorder was not seen in our patient , this is the first patient described with haploinsufficiency of PDE1C possibly causing developmental delay . - pubmed
We evaluated the role of surgery followed by either chemotherapy ( ChT ) alone or chemotherapy and thoracic radiotherapy ( ChT / TRT ) versus sequential ChT / TRT in patients with clinical stage I or stage II small cell lung cancer ( SCLC ) . - pubmed
Diffusion - Weighted Imaging in the Early Diagnosis of EBV Meningoencephalitis . - pubmed
DWI is a rapid pulse sequence that must be added to the routine MR imaging regimen in patients with suspected meningoencephalitis . - pubmed
INDICATIONS : Lateral unicompartmental osteoarthritis of the knee with genu valgum in young patients . - pubmed
POSTOPERATIVE MANAGEMENT : The patient is mobilized under load with 20 kg body weight for the first 6 postoperative weeks . - pubmed
RESULTS : We treated 23 patients with lateral cartilage damage ( grades 3 and 4 ) and genu valgum with medial closing osteotomy of the distal femur ( 6 men and 17 women ) . - pubmed
Individuals with this mutation ( likely with significantly increased levels of the hemoregulatory tetrapeptide in blood and tissues ) , may confer protection against fibrosis . - pubmed
Low - level laser therapy with 810 nm wavelength improves skin wound healing in rats with streptozotocin - induced diabetes . - pubmed
OBJECTIVE : The aim of present study was to evaluate whether low - level laser therapy ( LLLT ) can reverse the impaired wound healing process in diabetic rats . - pubmed
BACKGROUND DATA : Impaired wound healing in diabetic patients represents a major health problem . - pubmed
Recent studies have indicated that LLLT may improve wound healing in diabetic rats , but the optimal treatment parameters are still unknown . - pubmed
MATERIALS AND METHODS : Male Sprague - Dawley rats ( n=21 ) were randomly divided into three groups : a healthy control group , a diabetic sham - treated group , and a diabetic LLLT - treated group . - pubmed
RESULTS : In diabetic rats , the histology of LLLT - treated excisions revealed a similar healing response to that in nondiabetic controls , with significantly more mature granulation tissue than in the sham - treated diabetic control group . - pubmed
LLLT reduced the loss of tensile strength , and increased the incision wound stiffness significantly compared with sham - irradiated rats , but this did not achieve the same level as in the nondiabetic controls . - pubmed
CONCLUSIONS : Our study demonstrates that infrared LLLT can improve wound healing in diabetic rats . - pubmed
Ultrasound - guided rectus sheath block or wound infiltration in children : a randomized blinded study of analgesia and bupivacaine absorption . - pubmed
OBJECTIVES : Compare the effectiveness and bupivacaine absorption following USGRSB or wound infiltration ( WI ) for umbilical hernia repair in children . - pubmed
METHODS : A randomized blinded study comparing WI with USGRSB in 40 children undergoing umbilical hernia repair was performed . - pubmed
Induction chemotherapy - based larynx preservation protocols use chemotherapy to select exclusively patients with ' chemosensitive ' tumors for a nonsurgical treatment with radiation therapy . - pubmed
This study on pyriform sinus squamous cell carcinoma ( SCC ) is interested in the oncological outcome of treatment based on radiation therapy when offered to patients with tumors responding to induction chemotherapy . - pubmed
The role of cats in the eco - epidemiology of spotted fever group diseases . - pubmed
BACKGROUND : Mediterranean Spotted Fever ( MSF ) , whose etiological agent is R. - pubmed
Rickettsia felis , etiological agent of Flea - borne spotted fever , is mainly transmitted by the cat flea , Ctenocephalides felis . - pubmed
Effects of probiotic yogurt consumption on lipid profile in type 2 diabetic patients : A randomized controlled clinical trial . - pubmed
The purpose of this study was to compare the effect of probiotic and conventional yogurt on lipid profile in type 2 diabetes mellitus patients . - pubmed
CONCLUSION : It is suggested that probiotic yogurt consumption may be used as an alternative prevention approach and treatment method to improve dyslipidemia in patients with type 2 diabetes . - pubmed
A 45 - year - old Chinese man presented with a high fever , urine occult blood , and a low density lesion in the right kidney . - pubmed
Paraprotein interferences assays are known but rather unusual in clinical chemistry.we here report a paraprotein interference with a bicarbonate assay in a IgA kappa - type myeloma patient . - pubmed
The cryptococcal antigen lateral flow assay ( Immuno - Mycologics ) has revolutionized diagnosis of cryptococcosis and automated nucleic acid amplification assays hold promise for improving diagnosis of bacterial and mycobacterial meningitis . - pubmed
Hesperetin , a flavonoid from citrus fruits , has been proved to possess biological activity on various types of human cancers . - pubmed
This article aims to provide a review on current issues related to the " locomotor " state and interactions between spinal and supraspinal influences on the central pattern generator ( CPG ) circuitry in humans , which may be important for developing gait rehabilitation strategies in individuals with spinal cord and brain injuries . - pubmed
In this study , we sought to evaluate the role played by this receptor during early and late stages of infection with Mycobacterium avium in mice . - pubmed
What Is the Clinical Utility of Bedside Ultrasonography in the Diagnosis of Acute Cardiogenic Pulmonary Edema in the Undifferentiated Dyspneic Patient ? - pubmed
RESULTS : Candiduria was detected in 146 catheterized in - patients out of the 1,408 patients included in this study . - pubmed
Diabetes mellitus was associated with C albicans candiduria . - pubmed
The aim of this work was to explore the effect of glycine on endothelial dysfunction in aged rats . - pubmed
The patients completed a clinical examination , Knee Injury and Osteoarthritis Outcome Score ( KOOS ) and questionnaire evaluating QOL ( Eq5D-5L ) . - pubmed
UNLABELLED : The present retrospective multicenter study analyzed the effect of perioperative blood transfusions ( PBTs ) on the outcomes in 285 patients with upper tract urothelial carcinoma who had undergone radical nephroureterectomy ( RNU ) . - pubmed
We found that patients receiving PBTs had inferior survival compared with that of patients without PBTs . - pubmed
BACKGROUND : Preoperative anemia is an independent predictor for unfavorable outcomes in patients with upper tract urothelial carcinoma ( UTUC ) who undergo radical nephroureterectomy ( RNU ) . - pubmed
We investigated the impact of PBT on the outcomes of patients UTUC treated with RNU . - pubmed
PATIENTS AND METHODS : We analyzed the data from 285 patients with UTUC who had undergone RNU at 3 German academic institutions . - pubmed
CONCLUSION : PBT is an independent risk factor for worse overall survival in patients with UTUC treated with RNU . - pubmed
PURPOSE : To compare the clinical , microbiological and metabonomic profiles of subjects with high and low levels of chronic gingival bleeding during a controlled oral hygiene regimen intervention including sequential phases of rigorous therapeutic oral hygiene followed by experimental gingivitis ( EG ) . - pubmed
STUDY DESIGN : We performed a prospective two - armed cohort in a tertiary teaching hospital in Sao Paulo , Brazil , including 37 normotensive and 60 chronic hypertensive pregnant women . - pubmed
RESULTS : Among normotensive and chronic hypertensive pregnancies , 4 ( 10.8 % ) and 14 ( 23.3 % ) women developed preeclampsia and superimposed preeclampsia , respectively . - pubmed
Human Trial of a Genetically Modified Herpes Simplex Virus for Rapid Detection of Positive Peritoneal Cytology in the Staging of Pancreatic Cancer . - pubmed
INTRODUCTION : Patients with peritoneal dissemination of pancreatic adenocarcinoma do not benefit from surgical resection , but radiologic and cytologic detection of peritoneal cancer lack sensitivity . - pubmed
METHODS : Peritoneal washings from patients with pancreatic adenocarcinoma were incubated with the enhanced green fluorescent protein ( eGFP)-expressing oncolytic herpes simplex virus ( HSV ) NV1066 . - pubmed
These results were correlated with recurrence and survival for patients who underwent R0 resection . - pubmed
HSV - mediated fluorescence detection had sensitivities of 94 % and 100 % for detection of any and peritoneal metastatic disease ; respectively . - pubmed
Median recurrence free and disease specific survival were 6.5 and 18.3months for eGFP positive patients , versus 12.2 and 36.2months for eGFP negative patients ( P=0.01 and 0.19 ) ; respectively . - pubmed
CONCLUSIONS : A genetically modified HSV can be used as a highly sensitive diagnostic agent for detection of micro - metastatic disease in patients with pancreatic adenocarcinoma and may improve patient selection for surgery . - pubmed
Primary abscess of the iliopsoas muscle in children is uncommon , especially due to Streptococcus pyogenes ( group A streptococcus : GAS ) , which causes a variety of diseases ranging from pharyngitis to invasive life - threatening infection . - pubmed
RESULTS : TAC operation for 8 weeks produced a significant increase in left ventricular end - diastolic diameter and frequent occurrence of lethal arrhythmias after infusion of epinephrine and caffeine in TAC mice . - pubmed
Fetal infection with BVDV or BoHV-1 occurred in 4/23 group A offspring , 0/22 group B offspring , and 15/15 group C offspring . - pubmed
This research demonstrates efficacy of administering two pre - breeding doses of MLV vaccine with annual revaccination using CV vaccine to prevent fetal loss due to exposure to BVDV and BoHV-1 . - pubmed
[ Plasma and salivary markers of oxidative and carbonyl stress in patients with acute intermittent porphyria ] . - pubmed
The aim of our study was to investigate selected markers of oxidative and carbonyl stress in plasma and saliva in patients with AIP and to find out whether saliva could be used for monitoring the disease progression . - pubmed
METHODS : Blood and total non - stimulated saliva were collected from 16 patients with AIP in remission , and from 20 healthy individuals . - pubmed
RESULTS : Advanced glycation end products and thiobarbituric acid reacting substances in plasma and saliva were significantly higher in patients with AIP in comparison to the control group ( p & lt ; 0.001 ) and ( p & lt ; 0.05 ) . - pubmed
CONCLUSIONS : According to the best of our knowledge this is the first study to demonstrate increased concentrations of markers of oxidative and carbonyl stress and decreased antioxidant status of plasma and saliva in patients with AIP . - pubmed
METHODS : Patients presenting to hospital with acute asthma were examined during the exacerbation , and after 4 weeks recovery . - pubmed
RESULTS : Two male patients aged 28 and 5 years presented with MS with one patient presenting with concomitant AML . - pubmed
Ocular Surface Parameters Predicting Patient Satisfaction After a Single Vectored Thermal Pulsation Procedure for Management of Symptomatic Meibomian Gland Dysfunction . - pubmed
METHODS : This is a retrospective interventional case series ; it included consecutive patients who underwent bilateral VTP for management of symptomatic meibomian gland dysfunction ( MGD ) . - pubmed
CONCLUSIONS : VTP can be effective in treating dry eye symptoms of patients with MGD . - pubmed
Our data show that objective findings of dry eye , as evidenced by lower tear production , higher corneal and conjunctival staining scores , and higher osmolarity , tend to be markers present in the group of patients responding positively to VTP . - pubmed
Statin utilization improves oncologic and survival outcomes in patients with dyslipidemia and surgically treated renal cell carcinoma . - pubmed
BACKGROUND : We evaluated the role of statins in patients who underwent surgery for renal cell carcinoma ( RCC ) and who had dyslipidemia , as use of statins has been suggested to improve outcomes in RCC . - pubmed
METHODS : Two - center retrospective study of patients with dyslipidemia who underwent surgery for RCC from 7/1995 to 6/2005 . - pubmed
CONCLUSIONS : In RCC patients with dyslipidemia , statin use was associated with improved survival outcomes , and was an independent predictor of PFS . - pubmed
Further investigations are requisite to determine utility of statins in RCC patients . - pubmed
Matrix stiffness - induced reduction in unloaded shortening is more pronounced in cardiomyocytes isolated from obese ZSF1 rats with heart failure with preserved ejection fraction compared to lean ZSF1 rats . - pubmed
Additionally , cardiomyocytes isolated from stiff hearts of the obese ZSF1 rat model of heart failure with preserved ejection fraction show more pronounced reduction in unloaded shortening in response to matrix stiffening . - pubmed
This study aimed to explore the efficacy of 1 % ALN gel as local drug delivery ( LDD ) in adjunct to scaling and root planing ( SRP ) for the treatment of chronic periodontitis among smokers . - pubmed
Thus , 1 % ALN , along with SRP , is effective in the treatment of chronic periodontitis in smokers . - pubmed
The miRNA expression profile GSE41268 was extracted from Gene Expression Omnibus database , and differentially expressed miRNAs between whole saliva samples from patients with EC and healthy controls were identified using the Linear Models for Microarray Data package . - pubmed
A total of 18 differentially expressed miRNAs were identified in saliva samples from patients with EC , and 43 validated target genes corresponding to 7 upregulated miRNAs were identified . - pubmed
BACKGROUND : Among other factors , like the time from trauma to surgery or the number of axons that reach the muscle target , a patient 's age might also impact the final results of brachial plexus surgery . - pubmed
METHODS : Twenty pediatric patients ( under age 20 yr ) who had sustained a traumatic brachial plexus injury were compared against 20 patients , 20 to 29 yr old , and 20 patients , 30 yr old or older . - pubmed
Univariate , univariate trend , and correlation analyses were conducted with patient age , time to surgery , type of injury , and number of injured roots included as independent variables . - pubmed
METHODS AND ANALYSIS : In this randomised within - patient controlled pilot trial , 20 patients with hypertrophic CMs will be enrolled . - pubmed
Among these patients , 12 patients [ 4 with T - residual disease ( incomplete resection of primary tumor but complete dissection of regional lymph node ) , 8 with N - residual disease ( complete resection of primary tumor but incomplete resection of metastatic regional lymph node ) ] underwent 125I particle implantation during the operation , while the other 11 ( 4 with T - residual disease and 7 with N - residual disease ) received postoperative conventional radiotherapy . - pubmed
However , there was no significant difference in the rates of metastasis between the two groups for patients with N - residual disease . - pubmed
METHODS : We retrospectively reviewed 154 consecutive patients who underwent cystectomy for bladder cancer in two hospitals ( Hospital A and B ) between 2014 and 2016 . - pubmed
The liver functions of the patients reached normal levels before discharge and no additional liver lesions were found upon diagnostic imaging . - pubmed
This study encompasses the largest number of HP patients to date , but the surgical outcomes require further research and long - term follow - up . - pubmed
Our aim here was to examine the neurologic complications and our clinical experience in patients who underwent liver transplant for Wilson disease in our clinic . - pubmed
MATERIALS AND METHODS : We retrospectively reviewed the medical records of transplant patients with Wilson disease who were seen at Baskent University Faculty of Medicine Transplantation Science between 2005 and 2017 . - pubmed
Seven of 19 patients ( 36.8 % ) had neurologic symptoms , including epileptic seizures in 2 patients ( 10.5 % ) , encephalopathy in 1 patient ( 5.2 % ) , tremor in 3 patients ( 15.7 % ) , and headache in 1 patient ( 5.2 % ) . - pubmed
Patients with epileptic seizures were provided with seizure control medication ( levetiracetam ) . - pubmed
The most common complication seen in our patients was tremor . - pubmed
CONCLUSION : Targeted therapies are shifting the treatment paradigms and increasing survival for patients with PDAC , a group that used to have a grim prognosis . - pubmed
Long - Term Effect of Pulsed Nd : YAG Laser in the Treatment of Patients with Rotator Cuff Tendinopathy : A Randomized Controlled Trial . - pubmed
METHODS : Sixty patients with rotator cuff tendinopathy participated and completed the study . - pubmed
CONCLUSIONS : Pulsed Nd : YAG laser combined with an exercise program seems to be more effective in the treatment of patients with rotator cuff tendinopathy than a sham laser with exercises . - pubmed
The patient was able to ambulate normally at a walk without lameness four days postoperatively . - pubmed
Findings were graded using several neurologic impairment scales : two versions of the National Spina Bifida Patient Registry ( NSBPR ) classification , the International Standards for Neurological Classification of Spinal Cord Injury ( ISNCSCI ) motor level , and the Broughton Neurologic Impairment Scale . - pubmed
RESULTS : Data collected from 409 patient records showed significant correlations between Hoffer ambulation status and all neurologic impairment scales evaluated . - pubmed
AIMS / INTRODUCTION : Metformin , a widely prescribed antidiabetic agent , has been shown to exhibit anti - inflammatory effects in obese and type 2 diabetes patients , but the mechanism is not well elucidated . - pubmed
All patients are free of disease after 53 months of median follow - up ( range : 8 - 94 ) . - pubmed
BACKGROUND : Australia is committed to eliminating the hepatitis C virus ( HCV ) by 2030 . - pubmed
Among the risk factors assessed in this study , those responsible for the greatest decrease in under-5 LRI mortality between 1990 and 2017 were increased coverage of vaccination against Haemophilus influenza type b ( 11 4 % decrease , 0 0 - 24 5 ) , increased pneumococcal vaccine coverage ( 6 3 % decrease , 6 1 - 6 3 ) , and reductions in household air pollution ( 8 4 % , 6 8 - 9 2 ) . - pubmed
Data on genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from hyperlipidemic mouse strains . - pubmed
The data presented here are related to the research article , entitled Genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from hyperlipidemic mouse strains , published in Atherosclerosis 2019 Dec 3;293:1 - 10 ( D. Fuller , A.T. Grainger , A. Manichaikul , W. Shi ) . - pubmed
METHODS : In this pilot randomized controlled trial , twenty - eight patients with diagnosed , bothersome RLS were randomized to four treatment arms : no active intervention ( n = 7 ) , foot massager ( n = 8) , heat therapy ( n = 6 ) , and foot massager plus heat therapy ( n = 7 ) . - pubmed
To our knowledge , this is the oldest individual with typical parvovirus 19 - associated PPGSS reported to date . - pubmed
Comparison the effects of inhalation and massage aromatherapy with lavender and sweet orange on fatigue in hemodialysis patients : a randomized clinical trial . - pubmed
The aim of this study was to compare the effects of inhalation and massage aromatherapy with lavender and sweet orange on fatigue among hemodialysis patients . - pubmed
Conclusions Interventions with essential oils are effective in reducing fatigue in hemodialysis patients , although the effects of aromatherapy massage on fatigue are stronger than the effects of inhalation aromatherapy . - pubmed
There was one intra - operative pneumothorax , and two patients with superficial malignant tumours developed skin ulcerations . - pubmed
Objectives : To report the management of three consecutive patients with relapsing Staphylococcus aureus prosthetic knee infection ( PKI ) for whom explantation was not feasible who received a phage therapy during a " Debridement Antibiotics and Implant Retention " ( DAIR ) procedure followed by suppressive antimicrobial therapy . - pubmed
During surgery , all patients had poor local conditions including pus in contact to the implant . - pubmed
After a prolonged follow - up , mild discharge of synovial fluid persisted in two patients , for whom a subsequent DAIR was performed showing only mild synovial inflammation without bacterial persistence or super - infection . - pubmed
ABSTRACT : Neuropathic pain ( NeuP ) can be difficult to diagnose and manage in children . - pubmed
This observational cohort study recruited adolescents ( 10 - 17years ) with NeuP or complex regional pain syndrome ( CRPS ) . - pubmed
Background : To describe a clinical case of a cancer patient who underwent ablative tumor surgery , including treatment planning , surgical resection and subsequent implant rehabilitation . - pubmed
Case Report : A 61 - year - old patient with a diagnosis of multicystic follicular ameloblastoma in the maxilla , in which it was necessary a multidisciplinary approach and two surgical steps . - pubmed
Computed Tomography Angiography for the Diagnosis of Coronary Artery Disease Among Patients Undergoing Transcatheter Aortic Valve Implantation . - pubmed
At patient level , NPV for significant CAD was 88.6 % . - pubmed
CONCLUSION : Pre - TAVI CTA shows good performance for ruling out CAD and could be used as a gatekeeper for ICA in selected patients . - pubmed
Dual veno - arterial extra - corporeal membrane oxygenation support in a patient with refractory hyperdynamic septic shock : a case report . - pubmed
The hypodynamic septic shock appears to be a promising indication to veno - arterial membrane oxygenation ( VA - ECMO ) support of a patient with insufficient cardiac output . - pubmed
With cardiac recovery most of those patients progress into a hyperdynamic septic shock with cardiac output , which may not match critically low systemic vascular resistance to maintain perfusion pressures . - pubmed
We report a rare case of a 27 - year old patient who developed severe refractory hypodynamic septic shock due to the bilateral staphylococcal pneumonia and had to be initially rescued by femoro - femoral VA - ECMO . - pubmed
Treatment with streptokinase or heparin was allocated randomly to 20 patients with major pulmonary embolism verified by angiography . - pubmed
In the heparin group , 1 patient died from massive embolism 15 hours after the start of treatment . - pubmed
In another patient who died 4 weeks later from cerebral glibolastoma , persistent massive embolism contributed to the fatal outcome . - pubmed
Plasma levels were measured at different times during long - term flunarizine treatment ( duration 1 - -45 months , median : 6 months ) of 50 patients with intermittent claudication . - pubmed
The dialysate composition can be modified for the treatment of patients with acute renal failure . - pubmed
The effects of acutely induced metabolic and respiratory alkalosis with reduction of serum potassium concentration as well as chronic total body potassium depletion induced by furosemide treatment were evaluated and correlated with alteration of neuromuscular blockade induced by d - tubocurarine , pancuronium , and succinylcholine in 12 mongrel dogs . - pubmed
[ Granulocyte transfusion in the treatment of infections in patients with granulocytopenia ] . - pubmed
Implications of the monoclonal character of human atherosclerotic plaques . - pubmed
The evidence for the monoclonal nature of human atherosclerotic plaques is briefly reviewed . - pubmed
If we assume then that there is reason to accept the monoclonal character of atherosclerotic plaques in human beings then we are led to a search for the presence of factors that could " initiate " the monoclonal proliferation as well as factors that may promote the growth of the plaques . - pubmed
[ Effect of immunosuppressive agents on the dynamics of renal blood flow in patients with collagen diseases ] . - pubmed
Respiratory function tests ( forced vital capacity and forced expiratory volume in one second ) were performed serially in pregnancy , the puerperium , and at least six weeks post partum in 27 patients with a history of asthma and in 12 control subjects . - pubmed
The subjects are 11 patients with Parkinson ' s disease , 16 with Shy - Drager syndrome ( SDS ) , 16 with cerebellar cortical atrophy , 3 with Machado - Joseph disease , 3 with dentato - rubro - pallido - luysian atrophy and 2 with Huntington ' s disease as well as 24 controls . - pubmed
All patients with Parkinson ' s disease were administered levodopa and carbidopa . - pubmed
Therapy of infections in mice irradiated in mixed neutron / photon fields and inflicted with wound trauma : a review of current work . - pubmed
To evaluate therapies for sepsis in radiation casualties , we developed models of acquired and induced bacterial infections in irradiated and irradiated - wounded mice . - pubmed
In all mice , wounding after irradiation decreased resistance to infection . - pubmed
Therapy with S - TDCM for mice irradiated with either a mixed field or gamma rays increased resistance to Klebsiella pneumoniae - induced infections . - pubmed
pneumoniae infections in mice exposed to a mixed radiation field or to gamma rays was more effective than single - agent therapy . - pubmed
In all irradiated - wounded mice , single therapy of acquired infections with an antibiotic or S - TDCM did not increase survival . - pubmed
Survival of irradiated - wounded mice after topical application of gentamicin sulfate cream suggested that bacteria colonizing the wound disseminated systemically in untreated irradiated mice , resulting in death from sepsis . - pubmed
In lethal models of acquired infections in irradiated - wounded mice , significant increases in survival were achieved when systemic treatments with S - TDCM or gentamicin were combined with topical treatments of gentamicin cream . - pubmed
Therapies for sepsis in all mice exposed to a mixed field were less effective than in mice exposed to gamma rays . - pubmed
Although it is well known that serious electrocardiographic abnormalities are not infrequently associated with Duchenne ' s progressive muscular dystrophy ( DMD ) , there are few reports about pacing therapy for patients with muscular dystrophy . - pubmed
Because the daily activity of patients with rapidly progressive type of muscular dystrophy such as DMD is at a very low level , they do not require pacing therapy . - pubmed
TERalb was examined in awake Wistar rats with untreated IDDM induced by streptozocin infusion ( 65 mg / kg body wt i.v . ) - pubmed
Blood volume remained unchanged ; however , systemic protein concentration increased from 4.9 + /- 0.1 g / dl in controls to 6.4 + /- 0.4 g / dl in 15 - day IDDM rats . - pubmed
Fifty patients with signs and symptoms of chronic impingement syndrome and/or rotator cuff tear were evaluated with shoulder arthrograms and ultrasonography . - pubmed
Real - time ultrasonography is a diagnostically sensitive and specific noninvasive method to evaluate patients with shoulder impingement syndrome , leading to the recommendation that it be used as a primary imaging technique to obviate or supplement arthrography in evaluating rotator cuff disease . - pubmed
Clinical examination of heparin - Ca in myocardial infarction patients . - pubmed
25,000 IU / ml , Chemical Works of Gedeon Richter ) has been examined in 26 acute and 6 imminent myocardial infarction patients . - pubmed
Ten healthy male volunteers and 19 hospital patients ( 14 males and 5 females ) with lung tuberculosis cooperated for this investigations . - pubmed
Effect of dietary selenium and tumor status on the retention of 75Se by tissues and mammary tumors of DMBA - treated rats . - pubmed
The effects of the presence of mammary tumors on 75Se retention was examined in DMBA - treated rats . - pubmed
Tumor bearing rats fed varying amounts of Se exhibited an inverse linear dose response between dietary Se intake and tissue retention of 75Se in whole body , heart , lungs , ovaries , adrenals , spleen , and muscle . - pubmed
Tumor bearing rats excreted more 75 Se label in the urine compared to both control rats fed the same amount of Se and DMBA - treated animals that remained tumor free . - pubmed
By 7 d , the increased urinary excretion of the label resulted in significantly decreased retention of 75Se in blood , spleen , liver , lungs , and kidneys of tumor - bearing rats compared to tumor - free animals . - pubmed
These results suggest that tumor bearing animals have an accelerated urinary excretion of Se compared to animals without tumors and that tumors either have a very slow turnover of Se or a low priority for the element . - pubmed
ACFID is indicated for radiculopathy due to both soft and hard discs and can be particularly valuable in treating patients with disc herniation adjacent to a previous fusion or radiculopathy with multiple - level myelographic filling defects . - pubmed
Two hundred and nine consecutive patients who suffered acute trauma had their carpal scaphoids examined by a radiographic method comprising 4 oblique projections with 1.4 x magnification . - pubmed
Lower rates of thymidine incorporation into DNA of skin fibroblasts from patients with adenomatosis of the colon and rectum . - pubmed
A total of six chemodectomas of the carotid body or ganglion nodosum in four patients were treated with radiation therapy . - pubmed
One patient experienced complete regression of her bilateral carotid body tumors over the ensuing 2.5 years and the other 3 patients have had no evidence of disease progression of their chemodectomas for 2 , 3 , and 4.5 years , respectively . - pubmed
A study of a new compound with an original structure , teomorfolin [ N -( 7 '- theophylline acetyl ) morpholine ] , was performed in the rat to investigate interaction with experimentally induced dislipidaemic disturbance related to atherosclerotic disorders . - pubmed
Effects of Troxerutin on the hemorheological parameters of patients with moderate arterial hypertension . - pubmed
Hypercholesterolemia and aortic glycosaminoglycans of rabbits fed semi - purified diets containing sucrose and lactose . - pubmed
The Gynecologic Oncology Group conducted a Phase II trial of carboplatin in patients with measurable advanced squamous cell carcinoma of cervix . - pubmed
Gastrointestinal toxicity was severe in three patients ( 7.7 % ) . - pubmed
Obliteration of peripancreatic fat planes usually is considered an indicator of peripancreatic tumour infiltration in the presence of a malignant mass , or of inflammation of peripancreatic tissues in patients with pancreatitis . - pubmed
and a variety of phenotypic traits , production of several enzymes potentially involved in virulence , cytotoxicity for Chinese hamster ovary cells , and mouse lethality were unsuccessful . - pubmed
One patient treated with clozapine ( 8 months ) and nitrofurantoin ( 8 days ) developed a reversible granulocytopenia . - pubmed
One patient ( treated with a combination of drugs ) had clinically insignificant depression of the leucocytes and three of segmented granulocytes . - pubmed
Two patients developed cardiac insufficiency , and four epileptic seizures . - pubmed
It is concluded that clozapine is a potent antipsychotic drug offering particular advantages in the treatment of schizophrenic patients with a pronounced symptomatology and tendency towards developing extrapyramidal side effects . - pubmed
Caution is advised in patients with cardiac insufficiency and epilepsy . - pubmed
The association between phosphocreatine 's antifibrillatory action and its effect on the excitement propagation processes in the ischemic area was investigated under acute coronary arterial occlusion in dogs . - pubmed
[ Role of animals and birds as sources of Salmonella infections in man ( literature review ) ] . - pubmed
[ Comparative study of fluorescent antibody indirect reactions in Chagas ' disease , mucocutaneous leishmaniasis and kala - azar using various Leishmania and Trypanosoma antigens ] . - pubmed
Protocol for clinical therapeutic trials in human breast cancer in advanced stages ] . - pubmed
Field observation on the bionomics of Leptotrombidium deliensis , the vector of scrub typhus in the Pescadores . - pubmed
[ Modification of morphologic structure of human and rat kidneys in poisoning effects . - pubmed
Ureteral pressure and its response to autonomic stimulations were investigated in paraplegics with ureteral reflux and compared to the response in patients with primary reflux , paraplegics without reflux , normal individuals and a patient who had undergone lumbar sympathectomy . - pubmed
The predominant organisms found in perinatal infections were Staphylococcus aureus , Group B streptococci and Escherichia coli . - pubmed
The majority of the hospital - acquired infections was caused by Gram - positive cocci ( micrococci , Staph . - pubmed
Starvation of 300 g rats for 3 days decreased ventricular - muscle total protein content and total RNA content by 15 and 22 % respectively . - pubmed
In glucose - perfused working rat hearts in vitro , 3 days of starvation inhibited rates of protein synthesis in ventricles by about 40 - 50 % compared with fed controls . - pubmed
We conclude that the rates of protein turnover in the anterogradely perfused rat heart in vitro closely approximate to the rates in vivo in absolute terms , and that the effects of starvation in vivo are mirrored in vitro . - pubmed
The diagnostic value of bone scintigraphy in patients with low back pain . - pubmed
Bone scintigraphy has been studied in two groups of patients presenting with low back pain . - pubmed
In one group of 38 patients suffering " nonspecific " back pain , bone scintigraphy and laboratory findings were negative in 24 . - pubmed
By comparison , the bone scans were reviewed from another group of patients suffering previously known malignancy . - pubmed
Out of 138 patients , nearly 40 % showed a positive bone scan due to subsequently proven metastasis . - pubmed
The present findings indicate that bone scintigraphy is not a useful procedure in patients with long - standing low back pain who have normal radiographs and normal laboratory findings . - pubmed
The murine mutation CatFraser causes a cataract in both the mutant heterozygote ( C/+ ) and mutant homozygote ( C / C ) . - pubmed
Specimens of human breast tissues from the periphery of excised benign tumors , obtained from 17 pre - menopausal patients , were processed into slices and transplanted subcutaneously to 122 female Balb / c athymic nude mice . - pubmed
If the Columbian theory of origin of syphilis were correct , the longer syphilization of the West Indies might have tended to lessen the effects of the disease by attenuating Treponema pallidum . - pubmed
Cystoid macular oedema in aphakic patients . - pubmed
Disturbance of recent memory function in parkinsonian patients on anticholinergic therapy . - pubmed
In this study the anticholinergic drug , trihexyphenidyl , at low doses when administered chronically for one month to Parkinson disease patients caused a decrease in performance on recent but not immediate memory tests . - pubmed
Awareness of possible deterioration of memory function of parkinsonian patients on anticholinergic medication is necessary . - pubmed
The grim prognosis for patients with severe radiation injury of the intestine need not be considered unalterable . - pubmed
Yersinia enterocolitica and eye infection : a case report . - pubmed
The authors reported a culturally proven case of orbital cellulitis , uveitis and conjunctivitis due to Yersinia enterocolitica serotype 0:9 . - pubmed
As the clinical parallelism , all patients made a smooth convalescence . - pubmed
A double - blind study of 90 patients undergoing coronary angiography was performed to determine the safety and efficacy of 0.6 mg atropine sulfate in preventing contrast - induced bradycardia . - pubmed
Coronary angiography performed using the Sones technique resulted in ventricular pauses of greater than 2 seconds in 3 of 49 patients ( 6 % ) who received prophylactic atropine and 20 of 41 patients ( 49 % ) receiving placebo . - pubmed
To examine the basis of pulmonary constriction during chronic hypoxia , rat pulmonary artery rings were precontracted and exposed to multiple episodes of hypoxia . - pubmed
Forty subjects were clinically examined using scales for cerebellar , pyramidal , parkinsonian , and mental status and by quantitative evaluation of neuroimages . - pubmed
The patients were classified into two groups : cerebellar - plus and " pure " cerebellar syndromes . - pubmed
Patients with " pure " cerebellar syndrome were diagnosed as autosomal dominant cerebellar ataxia III ( ADCA III ) or " pure idiopathic " late - onset cerebellar ataxia ( ILOCA ) in this series . - pubmed
[ VM-26 plus CCNU in the prevention of brain metastasis in lung cancer patients ] . - pubmed
Brain metastasis is of frequent occurrence in patients with cancer of the lung . - pubmed
To ascertain if brain metastasis is preventable , 34 lung cancer patients without brain metastasis were treated with 4 cycles of VM-26 plus CCNU at 4 - week intervals . - pubmed
As a control for comparison , an equal number of lung cancer patients free of brain metastasis were treated with chemotherapy protocol which did not include VM-26 and CCNU . - pubmed
The results indicate that none of the VM-26 plus CCNU - treated patients developed brain metastasis while brain metastasis occurred in 7 ( 20.5 % ) of 34 control patients . - pubmed
[ Vaccination of cats against infection with feline leukemia virus ( FeLV ): first recombinant vaccine and the effect of a pre - existing infection with feline immunodeficiency virus ( FIV ) ] . - pubmed
In order to determine the effect of a pre - existing infection with feline immunodeficiency virus on the efficacy of vaccination , 50 % of the cats were previously infected with FIV . - pubmed
With prolonged duration of FIV infection the probability increases , that the immune system of the cat will fail and clinical signs will appear . - pubmed
In order to observe a state of possible immunodeficiency , an accurate clinical examination of every cat prior to vaccination seems of major importance . - pubmed
At the University of Pittsburgh Medical Center , four patients have undergone single - lung transplantation for lymphangioleiomyomatosis . - pubmed
We report a 21 - year - old man with agammaglobulinemia and chronic progressive encephalopathy . - pubmed
Viral isolations were negative and serum antibody titers for rubella , measles , and human immune deficiency virus were not elevated . - pubmed
Our patient 's symptoms resemble those previously reported as chronic progressive encephalopathy without viral isolation . - pubmed
Patients present with localized tenderness , induration , and pain with passive flexion of the gluteal muscles . - pubmed
The case history is presented of a man in whom a fistula between the oesophagus and left main bronchus was not diagnosed until the age of 48 . - pubmed
To investigate this we measured hypercapnic rebreathing responses in seven normal subjects ( six males , age range 21 - 38 years ) with and without an inspiratory resistive load of 10 cm H2O. - pubmed
Seventeen patients had myocardial atrophy , fibrosis , or both . - pubmed
Four ( 9.3 % ) of 43 patients without myocardial atrophy or fibrosis died as a consequence of other complications . - pubmed
EXPERIMENTAL DESIGN : We used electroporation and lipofectin transfection to introduce various transforming constructs , and direct infection with an oncogenic adeno 31 ( Ad31 ) virus to immortalize cells from freshly isolated rat kidney glomeruli and characterized the cells obtained at their 20th , 40th , 60th , and 80th passage for markers of various glomerular cell types . - pubmed
RESULTS : Direct infection with an oncogenic adenovirus type 31 ( Ad31 ) resulted in a stable cell line ( over 120 passages ) morphologically resembling epithelial / endothelial cells line ( over 120 passages ) morphologically resembling epithelial / endothelial cells . - pubmed
Based on the reported sex difference in the incidence of acquired cystic kidney disease ( ACKD ) in patients with chronic renal failure , it is hypothesized that the hormonal derangement , well documented in male and female uremic patients on long - term dialysis , could be responsible for the pathogenesis of ACKD . - pubmed
Children with idiopathic congenital bilateral vocal cord paralysis ( BVCP ) were investigated by electromyography ( EMG ) of the posterior cricoarytenoid and thyroarytenoid muscles to determine whether laryngeal EMG findings had diagnostic or prognostic significance . - pubmed
We describe a patient who developed a vesicular eruption shortly after an irritant dermatitis caused by the contact with a detergent containing sodium hypochlorite . - pubmed
We suggest a possible pathogenetic relationship between the chemical dermatitis and LABD in this patient . - pubmed
[ Neutropenic enterocolitis in children with cancer ] . - pubmed
OBJECTIVES : Neuropenic enterocolitis ( NEC ) is a destructive lesion of the ileocecal region occurring in cancer patients treated with chemotherapy . - pubmed
Our aim was to determine the incidence of NEC in children with cancer and to review the indications of surgery in these cases . - pubmed
MATERIAL AND METHODS : The records of children with cancer treated with chemotherapy in the last 6 years at Hospital Infantile La Paz were reviewed . - pubmed
We selected those patients who had abdominal pain and neutropenia and whose physical examination and radiological findings were consistent with NEC . - pubmed
CONCLUSION : Pediatric surgeons treating neutropenic cancer patients should be familiar with this condition , that must be suspected early in granulocytopenic patients with acute abdominal extension . - pubmed
Preretinal neovascularization induced by experimental retinal vein occlusion in albino rats . - pubmed
Retinal ischemia and neovascularization have been demonstrated in several animal models . - pubmed
To determine 1 ) whether the retinal or preretinal neovascularization can be induced in albino rats by retinal vein occlusion and 2 ) the type and rate of occurrence on neovascularization , we occluded retinal veins in albino rats by photodynamic thrombosis . - pubmed
These data suggest that preretinal neovascularization in albino rats can be induced by this minimally traumatic method and that venous occlusion is severe enough to compromise arterial blood flow for a certain threshold period , thus inducing the development of preretinal neovascularization . - pubmed
We , therefore , examined the effects of upper airway negative pressure on reflex palatal muscle activity in 16 normal nonsnoring awake male subjects and 16 awake SAHS patients using electromyography . - pubmed
Reflex electromyographic response to negative pressure was reduced in SAHS patients compared to normal subjects for both muscles ( p & lt ; 0.001 ) . - pubmed
When the seven thinnest SAHS patients were compared with seven normal subjects matched for BMI and age , the SAHS patients still demonstrated impaired responses to negative pressure for both muscles ( p & lt ; 0.001 ) . - pubmed
That mutations in human patched result in dysregulation of several genes known to play a role in both organogenesis and carcinogenesis may explain both the birth defects and the cancer predisposition seen in the nevoid basal cell carcinoma syndrome . - pubmed
OBJECTIVE : To analyze the clinical features , management , and outcome of patients with Castleman disease . - pubmed
PATIENTS : All patients with Castleman disease who were seen at Texas Medical Center , Houston , Texas , between 1977 and 1995 . - pubmed
MEASUREMENTS : Patients were identified according to initial presentation as having localized or multicentric Castleman disease . - pubmed
The 8 patients with multicentric disease were further subdivided according to initial treatment : Three patients who received combination chemotherapy are currently alive and free of disease ; 2 patients treated with prednisone are alive but have needed intermittent maintenance therapy for disease reactivations ; and 2 patients treated with surgery only have died , 1 of infectious complications and 1 of non - Hodgkin lymphoma . - pubmed
Sixty - seven children aged 5 - 15 years were induced to narcosis and narcotized with diprivan . - pubmed
The patients were operated on for appendicitis , peritonitis , osteomyelitis , phlegmons of different localization , and craniocerebral injuries . - pubmed
Cerebral ischemia after bilateral carotid artery occlusion and intraluminal suture occlusion in mice : evaluation of the patency of the posterior communicating artery . - pubmed
Cerebral ischemia models using mice have drawn increasing attention , particularly because of the availability of transgenic animals . - pubmed
However , the variability of intracranial vasculature at the circle of Willis in mice can influence the degree of ischemia in both the bilateral common carotid artery ( CCA ) occlusion and intraluminal suture occlusion models . - pubmed
We have developed a method to predict the extent of the anastomosis between carotid and vertebrobasilar circulation in three mouse strains ( C57BL/6 , CBA , and DBA/2 ) by measuring cortical microperfusion with laser Doppler flowmetry during a 1 - minute occlusion of both CCA . - pubmed
When animals showed residual cortical microperfusion of less than 12 % during bilateral CCA occlusion , the mice showed absence of functional anastomosis , developed ATP depletion in the frontal cortex during occlusion , and had ischemic neuronal death in the hippocampus and caudoputamen after occlusion for 15 minutes and recirculation for 7 days . - pubmed
Furthermore , those mice exhibited decreased local cerebral blood flow and associated ischemic neuronal death in the hippocampus , within the territory supplied by the posterior cerebral artery , with the intraluminal suture occlusion model . - pubmed
The current study demonstrates the need for assessment of intracranial vasculature in each animal by measuring cortical microperfusion during temporary occlusion of both CCA , no matter whether cerebral ischemia is produced by bilateral CCA occlusion or intraluminal suture occlusion in transgenic mice . - pubmed
HIV-1 - induced perturbations of glycosphingolipid metabolism are cell - specific and can be detected at early stages of HIV-1 infection . - pubmed
Rats were treated orally for 7 d with dihydrotachysterol , which produced significant hypercalcemia with a 15 + /- 2 % increase in plasma calcium concentration . - pubmed
Tuberculosis continues to be a worldwide problem for both humans and animals . - pubmed
The development of tests to differentiate between infection with Mycobacterium tuberculosis or Mycobacterium bovis and vaccination with M. - pubmed
Iron loading produced by TMH - ferrocene is highly efficient and , of the compounds used to produce iron loading in experimental systems , most closely mimics the loading patterns observed in the human disease hemochromatosis . - pubmed
The role of cranial MRI in identifying patients suffering from child abuse and presenting with unexplained neurological findings . - pubmed
OBJECTIVE : The aim of this study was to demonstrate the usefulness of cerebral MRI to detect possible child abuse in children with unexplained neurologic findings . - pubmed
METHOD : Between 1990 and 1997 , 208 children were referred for suspected physical child abuse to the Child Protection Clinic of Ste - Justine Hospital , a tertiary care pediatric hospital . - pubmed
Human seminal plasma protein allergy : a diagnosis rarely considered . - pubmed
Women with seminal plasma protein allergy ( SPPA ) have an immunologic response to human semen . - pubmed
Percutaneous transluminal coronary angioplasty is a routinely used non - surgical revascularization technique for patients with coronary artery disease . - pubmed
Rabies is enzootic in raccoons ( Procyon lotor ) in the eastern United States . - pubmed
Oral vaccination of free - ranging raccoons against rabies has the potential to control the disease in a principal reservoir and reduce the risk of rabies exposure among domestic animals and humans . - pubmed
Indications for filter placement were : recent pulmonary embolism ( PE ) or proximal deep vein thrombosis ( DVT ) with a contraindication to anticoagulation ( 11 patients ) , massive PE treated with thrombolytic therapy ( one patient ) , PE with heparin - induced thrombocytopenia ( one patient ) , and prophylaxis after major trauma ( two patients ) . - pubmed
Patients were followed for inferior vena cava ( IVC ) thrombosis , bleeding , and recurrent DVT or PE . - pubmed
In order to understand the role of different glial cells in this process , we analysed the proliferation pattern of glial cells in central ( CNS ) and peripheral ( PNS ) parts of the dorsal root and the segmental white and grey spinal cord matter after dorsal rhizotomy or sciatic nerve transection in adult rats 1 - 7 days after injury . - pubmed
BACKGROUND : Retrospective study in pediatric patients with Cornelia de Lange syndrome undergoing different surgical operations , in order to critically evaluate the anesthesiologic aspects of this syndrome . - pubmed
METHODS : Between January 1997 and December 1998 , 42 patients undergoing diagnostic examinations ( esophagogastroscopy , oculistic visit ) or surgery ( total exodontia , fundoplicatio for esophageal reflux , correction of labiopalatoschisis ) have been studied . - pubmed
CONCLUSIONS : Short neck , ogive palatum , cleft palate , micrognatia , urogenital and gastroenteric anomalies , esophageal reflux , together with heart defects ( 15 % of cases ) , can complicate the peri and postoperative period in these patients . - pubmed
A careful preoperative evaluation and a careful perioperative management , may decrease anesthetic complications in Cornelia de Lange syndrome to the same range of normal patients . - pubmed
Syncytium formation by HSV-1 strain HF was inhibited , and small plaques with rounded cells were formed in Conmy A - treated cell cultures . - pubmed
METHODS : From 3320 pregnant women who had delivered in our hospital and undergone the oral glucose tolerance test for various risk factors over a three - year period , 163 with alpha - thalassaemia trait were identified ( study group ) . - pubmed
PURPOSE : We previously showed that mitomycin C activity in human bladder tumors is inversely related to tumor stage and muscle invasive tumors are less sensitive than superficial tumors . - pubmed
The perfusion of human tumour xenografts was manipulated by administration of diltiazem and pentoxifylline , and the extent that observed changes in tumour perfusion altered tumour radiosensitivity was determined . - pubmed
This study examines the incidence , predictors , and evolution of postoperative atrioventricular block ( AVB ) after mitral valve repair ( MVR ) in 115 consecutive patients using Carpentier 's technique ( between November 1996 and April 1997 ) . - pubmed
Postoperative AVB occurred in 27 patients ( 23 % ) . - pubmed
Second - degree AVB ( Mobitz type I ) occurred in 4 patients ( 3 % ) immediately after operation and resolved in all before hospital discharge . - pubmed
Isolated first - degree AVB occurred in 16 patients ( 14 % ) and was permanent in 12 . - pubmed
Three patients ( 2.6 % ) had permanent pacemaker implantation , on average 18 days after operation , and all had persistent third - degree AVB . - pubmed
Following lesions were found : hepatocellular carcinoma ( 5 patients ) , hemangioma ( 2 ) , metastasis ( 1 ) , cyst ( 1 ) , adenoma ( 1 ) . - pubmed
METHODS : One hundred ninety - six consecutive patients ( predominantly teenagers ) previously unsuccessfully treated by surgery underwent CO2 laser for recurrent onychocryptosis . - pubmed
One patient developed a neuroma in the lateral nail groove . - pubmed
This may be seen in patients with temporal lobe or other forms of focal epilepsy , in the epileptic encephalopathies such as West and Lennox Gastaut Syndromes and even in some patients with idiopathic generalized epilepsy . - pubmed
Neuroimaging diagnostics of cerebral hemorrhage in congenitally afibrinogenic patients may be compromised by different pitfalls . - pubmed
We describe the case of a 28 - year - old patient with the diagnosis of congenital afibrinogenemia who suffered a large intracerebral hemorrhage . - pubmed
Use of Punica granatum as an antifungal agent against candidosis associated with denture stomatitis . - pubmed
The aim of this study was to evaluate the use of a gel containing the extract of Punica granatum as an antifungal agent against candidosis associated with denture stomatitis . - pubmed
Sixty patients with denture stomatitis confirmed by clinical and mycologic examination were selected . - pubmed
Participants were screened for syphilis , chlamydia , and gonorrhea and were also offered HIV testing . - pubmed
Of 2229 urine samples , 185 ( 8.3 % ) tested positive for Chlamydia trachomatis and 108 ( 4.9 % ) positive for Neisseria gonorrhoeae . - pubmed
This study examined discourse ability in children with stroke as compared with orthopedic controls , age - at - injury , and lesion effects . - pubmed
[ Chronic cor pulmonale in patients with pulmonary fibrosis ] . - pubmed
ISOLATING PATIENTS WITH STAPHYLOCOCCAL INFECTIONS . - pubmed
Of the 1 113 strains , 66 strains were influenza A - H1N1 , 544 strains were influenza A - H3N2 viruses while 98 and 405 strains belonged to B / Yamagata and B / Victoria viruses with the rates of isolation on each subtype were 5.9 % , 48.9 % , 8.8 % and 36.4 % , respectively . - pubmed
CONCLUSIONS : Although influenza A subtype H1N1 and H3N2 as well as B type viruses were co - circulating in our country , the influenza A ( H3N2 ) and B / Victoria isolates were found the predominant strains in the period of this study which were different from the previous years . - pubmed
Finally , PV patients had higher oxidative burst and PNC than T - nPV patients or HC ( P & lt ; 0.05 ) . - pubmed
CONCLUSION : Total glossectomy is an oncologically sound surgical procedure that should only be performed in carefully selected patients with advanced malignancies affecting the tongue . - pubmed
Genes and mutations in human idiopathic epilepsy . - pubmed
Thirteen genes have already been identified in human idiopathic epilepsies since 1995 , but they account only for a minority of all epilepsy cases . - pubmed
We recruited 50 men with advanced prostate cancer who elected to receive hormonal therapy to be randomized to 1 of 3 flutamide treatment groups : 1 ) 250 mg once daily , 2 ) 250 mg twice daily , or 3 ) 250 mg 3 times daily for 3 months , after which the therapy of their choice was instituted . - pubmed
Aberrant methylation of promoter CpG islands in human genes is an alternative genetic inactivation mechanism that contributes to the development of human tumors . - pubmed
We report a patient with renal cell carcinoma who had an intracaval tumor thrombus that had extended into the right spermatic vein . - pubmed
This study quantified the influence of visual attention therapy on the reading comprehension of Grade 6 children with moderate reading disabilities ( RD ) in the absence of specific reading remediation . - pubmed
[ Endoscopic resection of benign prostatic hyperplasia in men over 80 years of age : a retrospective study of 184 cases ] . - pubmed
OBJECTIVE : The aim of the present study was to evaluate the outcome of transurethral resection of the prostate for benign prostatic hyperplasia in men over 80 years . - pubmed
MATERIAL AND METHOD : 184 men over 80 years underwent transurethral resection of the prostate for benign prostatic hyperplasia . - pubmed
CONCLUSION : Transurethral resection of the prostate for benign prostatic hyperplasia in men over 80 years has a good outcome with an acceptable morbidity and mortality . - pubmed
Sera from newly diagnosed type 1 diabetes patients ( n=61 ) were studied using both approaches . - pubmed
A 44 - year - old man presented with a rare subfrontal schwannoma with headache . - pubmed
The patient was discharged without hyposmia . - pubmed
A 30 - year - old white man presented with a sporadic form of gradually progressive spastic gait and , later , supranuclear vertical and horizontal gaze palsy , mild cognitive impairment , loss of postural reflexes , and falls . - pubmed
Treatment began at 6 weeks of age when animals are insulin resistant and hyperinsulinemic , but not yet hyperglycemic , and ended at 12 weeks of age , which is 4 weeks after ZDF rats typically develop overt diabetes . - pubmed
BMOV and RSG treatment also prevented the hyper - phagia and polydipsia present in untreated ZDF rats ; however , BMOV - treated ZDF rats gained much less weight than did RSG - treated animals . - pubmed
However , it is not fully understood whether and how RXM suppresses angiogenesis in human hepatoma , which is a well - known hypervascular tumor . - pubmed
MATERIALS AND METHODS : In the present study , we examined the effects of RXM on tumor angiogenesis in the human hepatoma cell line , HepG2 . - pubmed
Because RXM is widely used in clinical practice , it may represent an effective new strategy for human hepatoma therapy . - pubmed
Leflunomide reduces nitric oxide production in patients with active rheumatoid arthritis . - pubmed
We carried out this study to determine if there was alteration in NO production in patients with RA . - pubmed
METHODS : An 8 - week open label study was carried out on patients with adult onset active RA . - pubmed
RESULTS : Thirty - three patients with active RA were enrolled for this study . - pubmed
CONCLUSIONS : Leflunomide inhibits nitric oxide production in patients with active RA . - pubmed
The inflammation in cystic fibrosis ( CF ) patients with chronic Pseudomonas aeruginosa lung infection is dominated by polymorphonuclear neutrophils ( PMNs ) . - pubmed
The Norwegian Doloplus-2 , a tool for behavioural pain assessment : translation and pilot - validation in nursing home patients with cognitive impairment . - pubmed
BACKGROUND : Pain assessment is challenging in cognitively impaired ( CI ) patients due to inadequate self - report skills and observational ratings are an alternative . - pubmed
Femoral fractures are common in this patient population , and management presents a unique technical challenge . - pubmed
This case series describes the long - term management of nine osteopetrotic femoral fractures in three patients . - pubmed
An unusual type of single coronary artery anomaly in a patient with hypertrophic obstructive cardiomyopathy . - pubmed
The basic process of reactive astrocytosis is conserved in vertebrate evolution , suggesting fitness - enhancing benefits , but scar - forming reactive astrocytes are often regarded as uniformly detrimental to clinical outcome , in particular , when implicated as inhibitors of axon regeneration . - pubmed
A seven - year - old girl received intramuscular injection of diclofenac for symptomatic treatment of her fever . - pubmed
Vitamin E and C supplementation prevents decrease of eicosapentaenoic acid in mononuclear cells in chronic hepatitis C patients during combination therapy of interferon alpha-2b and ribavirin . - pubmed
First line treatment with beta - blockers followed by adjuvant ACE inhibitors after six months may be safe in older people with heart failure . - pubmed
CONCLUSIONS : The occurrence of stroke in patients with atrial fibrillation is modestly higher during the winter . - pubmed
Although serum testosterone levels decrease acutely in critically ill patients , estrogen levels rise . - pubmed
Animal studies suggest that these opposing changes in circulating estrogen and androgen levels may be important to reduce morbidity and mortality in critical illness . - pubmed
Human colon adenocarcinoma cells ( HT29 - ATCC ) and the clone HT29 - 5F7 were cultured under conditions that differentiate cells to a polarized intestinal phenotype . - pubmed
Gargling with tea catechin extracts for the prevention of influenza infection in elderly nursing home residents : a prospective clinical study . - pubmed
CASE REPORT : A 32 - year - old man presented with severe upper abdominal pain radiating to the back , associated with vomiting and abdominal distension . - pubmed
The patient was diagnosed as having had chronic calcific pancreatitis recently and had undergone ERCP with pancreatic duct stenting elsewhere . - pubmed
Two days after the procedure , the patient developed severe abdominal pain , vomiting and abdominal distention , and patient was referred to our hospital 7 days after the procedure . - pubmed
This patient had a life - threatening complication following pancreatic duct stenting for chronic pancreatitis and was managed medically . - pubmed
The Ts65Dn mouse , a genetic model of DS , exhibits phenotypes of DS , including memory impairments indicative of hippocampal dysfunction . - pubmed
[ The level of cotinine - marker of tobacco smoking , in patients with hyperthyroidism ] . - pubmed
INTRODUCTION : Orbitopathy associated with Graves ' disease TAO ( thyroid associated orbitopathy ) is likewise connected with environmental factors including tobacco smoking . - pubmed
Tobacco smoking increases the risk of ophthalmologic pathology and leads to the orbital tissue damage due to the hypoxia . - pubmed
The aim of the study was to correlate the concentration of urinecotinine ( marker of tobacco smoking ) in Graves ' disease patients with TAO with points received on the Fagerstrom questionnaire . - pubmed
MATERIALS AND METHODS : Thirty women with different degree of exacerbation of TAO in Graves ' disease ( 34.28 + /- 12.04 yr . ) - pubmed
As control we used 29 women with Graves ' disease without TAO ( 29.35 + /- 12.33 yr . ) - pubmed
In patients with Graves ' disease with TAO the highest score of tobacco smoking has been found in persons with the highest ophthalmopathy exacerbation . - pubmed
None of the patients had any postoperative complications . - pubmed
No patients had any tumor recurrence during followup . - pubmed
INTRODUCTION : Esophageal stricture is a common complication following combined chemotherapy and radiation for advanced oropharyngeal cancer and severely compromises patients ' quality of life . - pubmed
However , the near complete , or complete , stenosis seen in some of these patients may also be unamenable to retrograde endoscopic dilation . - pubmed
METHODS : Seven patients with advanced head and neck cancer treated with combined chemotherapy and radiation developed severe dysphagia requiring intervention for near total , or total , upper esophageal stenosis . - pubmed
RESULTS : The first patient in the series developed a pneumothorax during attempted passage of the guidewire in a retrograde fashion . - pubmed
CONCLUSIONS : A retrograde endoscopic progressive balloon dilation for esophageal dilation under direct visualization provides palliation of swallowing difficulties in patients whose stenoses are not amenable to traditional techniques . - pubmed
Long - term outcome of intensive chemotherapy for adults with de novo acute myeloid leukaemia ( AML ): the nationwide AML-92 study by the Finnish Leukaemia Group . - pubmed
PATIENTS AND METHODS : A total of 327 consecutive patients with de novo AML ( promyelocytic leukaemia excluded ) aged 16 - 65 yr were recruited into the study between September 1992 and December 2001 . - pubmed
Median relapse - free survival ( RFS ) for the patients not transplanted in the first CR ( n = 195 ) was 1.7 yr ( 95 % CI : 0.81 - 2.60 ) . - pubmed
The 5 - yr survival was 71 % , 47 % and 37 % for the non - transplanted patients ( n = 202 ) with favourable , intermediate / normal and intermediate / abnormal karyotypes , respectively , while only 8 % of the patients having adverse karyotype were alive at 5 yr ( P & lt ; 0.01 ) . - pubmed
Of the patients with favourable , intermediate / normal or intermediate / abnormal karyotypes , respectively , 58 % , 41 % and 31 % were expected to be alive at 10 yr . - pubmed
CONCLUSIONS : Idarubicin- and cytarabine - based intensive chemotherapy regimen is very effective in de novo AML for adult patients up to 65 yr of age . - pubmed
In these patients acetabular loosening was confirmed , requiring reoperation . - pubmed
Prenatal exposure to cocaine has been associated with cognitive deficits in children and in animal models . - pubmed
METHODS : Twenty - six patients with recurrent flares of non - specific balanitis were randomly assigned to 1 group applying pimecrolimus cream 1 % and 1 group applying placebo on the glans twice daily for 7 days . - pubmed
A peptide - gated ion channel from the freshwater polyp Hydra . - pubmed
Only in the last couple of years , an ever - growing number of human genetic diseases in the synthesis of glycoproteins have been identified . - pubmed
Immunorestoration and augmentation of mitogen lymphocyte response in Graffi tumor bearing hamsters by purified saponin mixture from Astragalus corniculatus . - pubmed
( Fabaceae ) on mitogen response of the spleen cells in Graffi tumor bearing ( GTBH ) and healthy hamsters were reported . - pubmed
Perinatal outcomes in severe preeclamptic women between 24 - 33(+6 ) weeks ' gestation . - pubmed
MATERIAL AND METHOD : A retrospective descriptive study of 99 women with severe preeclampsia between 24 - 33(+6)-week gestation who delivered at the King Chulalongkorn Memorial Hospital from January 2002 to December 2005 was included . - pubmed
Retraction : Impact of aortic arch stiffness on recurrence of stroke in patients with acute ischemic stroke . - pubmed
CCV therefore represents a new avian virus of the genus Circovirus of the family Circoviridae , and is more closely related to CoCV than BFDV.The availability of nucleotide sequence data will facilitate the development of DNA - detecting diagnostics with which the prevalence of CCV infections can be assessed . - pubmed
Enhanced estrogen - induced proliferation in obese rat endometrium . - pubmed
OBJECTIVE : We tested the hypothesis that the proliferative estrogen effect on the endometrium is enhanced in obese vs lean animals . - pubmed
STUDY DESIGN : Using Zucker fa / fa obese rats and lean control , we examined endometrial cell proliferation and the expression patterns of certain estrogen - regulated proproliferative and antiproliferative genes after short - term treatment with estradiol . - pubmed
RESULTS : No significant morphologic / histologic difference was seen between the obese rats and the lean rats . - pubmed
CONCLUSION : Enhancement of estrogen - induced endometrial proproliferative gene expression and suppression of antiproliferative gene expression was seen in the endometrium of obese vs lean animals . - pubmed
We report the case of an infant with BP successfully treated with oral corticosteroids . - pubmed
Prevention of selenite - induced cataractogenesis by N - acetylcysteine in rats . - pubmed
PURPOSE : To evaluate the effect of N - acetylcysteine on selenite - induced cataract formation in a rat model . - pubmed
None of the rats in group 3 developed any lens opacity . - pubmed
CONCLUSIONS : N - acetylcysteine appears to inhibit selenite - induced cataractogenesis in the rat model , and this seems to be caused by the prevention of oxidative damage . - pubmed
The prognostic significance of bundle branch block in high - risk chronic stable vascular disease patients : a report from the HOPE trial . - pubmed
OBJECTIVE : The prognostic significance of left and right bundle branch block ( LBBB and RRBB ) in patients with chronic stable cardiovascular ( CV ) disease is not well characterized and was evaluated in the Heart Outcomes Prevention Evaluation ( HOPE ) study cohort . - pubmed
SETTING AND PATIENTS : HOPE was a multicenter , international trial , which evaluated ramipril and vitamin E in 9,541 patients aged & gt ; or = 55 years with CV disease or diabetes with & gt ; or = 1 CV risk factor(s ) but without heart failure ( HF ) or known left ventricular systolic dysfunction . - pubmed
RESULTS : Baseline LBBB was present in 246 ( 2.6 % ) patients and was associated with increased risk for major CV events ( HR = 1.54 ; 95 % CI , 1.18 - 2.02 ) , CV death ( HR 2.29 ; 95 % CI , 1.63 - 3.20 ) , heart failure ( HR 2.99 ; 95 % CI , 2.31 - 3.87 ) , sudden death ( HR 3.17 ; 95 % CI , 2.13 - 4.73 ) , and all - cause death ( HR = 2.10 ; 95 % CI , 1.59 - 2.77 ) . - pubmed
CONCLUSIONS : In patients with stable chronic CV disease , LBBB but not RBBB is an independent predictor of heart failure , sudden death , CV death , and all - cause death . - pubmed
MATERIALS AND METHODS : In this descriptive study we examined diagnostic and symptom data from a large cohort of patients with schizophrenia ( n = 133 ) , schizoaffective disorder ( n = 101 ) , or bipolar I disorder ( n = 186 ) . - pubmed
MPs are elevated in diabetic patients however studies have found differences in the MP profile in relation to disease type and the presence or absence of MPs . - pubmed
Interestingly , elevated endothelial cell - derived MP levels are predictive in identifying a subpopulation of diabetic patients without typical anginal symptoms who have angiographic evidence of coronary artery disease . - pubmed
The patients were followed throughout treatment , and the number of white spot lesions was noted at debonding . - pubmed
Plants accumulate free L - proline ( Pro ) in response to abiotic stresses ( drought and salinity ) and presence of bacterial pathogens , including the tumor - inducing bacterium Agrobacterium tumefaciens . - pubmed
Though many studies , mostly carried out in animal models , have linked dysfunctions of single neurotransmitter systems with the pathogenesis of HE , reports concerning neurotransmitter receptor alterations are controversial . - pubmed
MATERIALS AND METHODS : A total of 22 neonates ( 13 girls and 9 boys ; mean gestational age , 40 weeks + /- 9 days ; birth weight , 3203 + /- 584 g ) underwent brain MR imaging between day 1 and day 6 after birth ; 6 - noncollinear direction DTI was performed . - pubmed
results of a randomized study in head and neck cancer patients . - pubmed
PATIENTS AND METHODS : 39 patients ( 8 female , 31 male ) with advanced head and neck cancer were included in a randomised phase II study . - pubmed
Tumour localizations : oral cavity 15 patients , oropharynx 19 patients , hypopharynx 5 patients , carcinoma of unknown primary 1 patient . - pubmed
The weekly patient analysis ( Student 's t - test ) showed a significant reduction of dysphagia in the selenium group ( Group 1 ) at the last week of irradiation . - pubmed
A 93 - year - old man presented with jaundice and fever . - pubmed
PURPOSE : Anxiety is common in patients undergoing radiation therapy ( RT ) and in their family caregivers ( FCs ) . - pubmed
This study aimed to identify distinct latent classes of oncology patients and their FCs based on self - reported anxiety symptoms from the beginning to four months after the completion of RT . - pubmed
METHOD : Using growth mixture modeling ( GMM ) , longitudinal changes in Spielberger State Anxiety Inventory ( STAI - S ) scores among 167 oncology outpatients with breast , prostate , lung , or brain cancer and 85 FCs were evaluated to determine distinct anxiety symptom profiles . - pubmed
The results emphasise the importance of familiar human relationships in reducing the feelings of loneliness in people experiencing dementia . - pubmed
We describe a 45 - year - old woman with peripheral embolism in whom echocardiography revealed mobile masses in the aortic arch that were characterized as atherothrombi . - pubmed
[ Characterization of Vibrio parahaemolyticus obtained from environment and cases of foodborne disease in Shenzhen , during 2006 - 2008 ] . - pubmed
OBJECTIVE : To analyze the serological and genetic divergence in the Vibrio parahaemolyticus from environment and cases of foodborne disease , and to compare these two groups in terms of virulence and other biological traits . - pubmed
Assessing global and regional left ventricular myocardial function in elderly patients using the bidimensional strain method . - pubmed
POPULATION AND METHODS : Patients without history of cardiac disease were enrolled from the geriatric department . - pubmed
Global longitudinal strain was significantly lower in elderly patients ( -20.9 + -1.9 % vs. -22.2 + -2.2 % , P<0.01 ) . - pubmed
Such living threads have the advantage of being a particularly mild culturing medium for mammalian cells , protecting the cells during subsequent processing steps from dehydration and other rapid changes in the chemistry of the surrounding environment . - pubmed
Staphylococcus aureus was the most common pathogen , causing 9 HAIs ( 15.5 % ) . - pubmed
The combined use of surgery and radiotherapy to treat patients with epidural cord compression due to metastatic disease : a cost - utility analysis . - pubmed
We enrolled 14 hypertensive patients ( seven males , seven females , 70 + - 6 years old ) undergoing a monotherapy of amlodipine , efonidipine or cilnidipine into this prospective , open - labeled , randomized , crossover study . - pubmed
The nine encephalitis patients presented with altered mental state and seizures , tremor , weakness , or paralysis . - pubmed
All patients with encephalitis developed cerebral peduncle involvement on early magnetic resonance imaging ( MRI ) . - pubmed
These findings may help clinicians predict the neurological outcome when evaluating patients with MVE . - pubmed
METHODS : Patients diagnosed with AML or ALL between the ages of 0 and 18 years who survived at least 5 years after diagnosis were included in analysis . - pubmed
Cumulative incidences of secondary malignancy at 30 years for ALL patients and AML patients were 3.9 and 4.3 % , respectively ( p = 0.10 ) . - pubmed
Unfortunately , antiepileptic drug therapy fails to control seizure activity in a relevant percentage of epilepsy patients . - pubmed
Epidemiological data as well as findings in human epileptic tissue and in rodent models indicate that drug resistance is a multi - factorial phenomenon with various factors contributing to therapeutic failure . - pubmed
Further proof is obviously needed regarding the relative functional relevance of blood - brain barrier efflux for antiepileptic drug efficacy in epilepsy patients . - pubmed
About 500,000 new cancer patients will develop brain metastases in 2013 . - pubmed
The primary treatment modality for these patients is partial or whole brain irradiation which leads to a progressive , irreversible cognitive impairment . - pubmed
Today , the proportion of diabetic patients receiving statins is increasing due to their beneficial effect on cardiovascular mortality . - pubmed
Tuberculosis ( TB ) and Tuberculous meningitis ( TBM ) caused by Mycobacterium tuberculosis ( MTB ) continue to be a major cause of morbidity and mortality . - pubmed
Up to one - half of patients with olfactory dysfunction improve over time . - pubmed
Human papillomaviruses are the causative agents of several cancers , but only a minority of HPV infections progress to malignancy . - pubmed
The association of pre - existing left atrial fibrosis with clinical variables in patients referred for catheter ablation of atrial fibrillation . - pubmed
We sought to determine pre - ablation , clinical characteristics that associate with the extent of LA fibrosis in patients undergoing catheter ablation for AF . - pubmed
METHODS AND RESULTS : Consecutive patients presenting for catheter ablation of AF were enrolled and underwent LGE - MRI prior to initial AF ablation . - pubmed
The extent of fibrosis as a percentage of total LA myocardium was calculated in all patients prior to ablation . - pubmed
Of 60 patients enrolled in the cohort , 13 had & lt;5 % fibrosis ( Group 1 ) , 15 had 5 - 7 % fibrosis ( Group 2 ) , 17 had 8 - 13 % fibrosis ( Group 3 ) , and 15 had 14 - 36 % fibrosis ( Group 4 ) . - pubmed
CONCLUSION : The extent of LA fibrosis in patients undergoing AF ablation is associated with AF type and time in continuous AF . - pubmed
We present a fatal case of a 59 - year - old woman with a clinical course complicated by venous thrombosis and pulmonary thromboembolism that was attributed to CCCO discovered initially at autopsy . - pubmed
Our method is distinguished from conventional forward genetic methods because it permits ( 1 ) unbiased declaration of mappable phenotypes , including those that are incompletely penetrant ( 2 ) , automated identification of causative mutations concurrent with phenotypic screening , without the need to outcross mutant mice to another strain and backcross them , and ( 3 ) exclusion of genes not involved in phenotypes of interest . - pubmed
Now one can assess blood flow and oxygenation changes resulting from functional activity and image functional response in disease models such as stroke and seizure , and even conduct long - term imaging of tumor physiology , all without the confounding effects of anesthetics or animal restraints . - pubmed
These advances are shedding new light on mammalian brain organization and function , and helping to elucidate loss of this organization or ' dysfunction ' in a wide array of central nervous system disease models . - pubmed
METHODS : One hundred and thirty - nine treatment - naive genotype 1 chronic hepatitis C patients with no history of TD or treatment with thyroid hormones were enrolled in this study . - pubmed
Three of the one hundred and fifteen patients without TPOAb at baseline developed TD at the end of treatment ( 37.5 % vs 2.6 % , P = 0.000 ) . - pubmed
Female patients exhibited an increased risk for developing TD compared with male patients ( P = 0.014 ) . - pubmed
Infection control strategies that successfully controlled an outbreak of Mycobacterium abscessus at a cystic fibrosis center . - pubmed
Data on the outcomes of M abscessus outbreaks and the efficacy of specific infection control procedures in patients with CF remain limited . - pubmed
Following an M abscessus outbreak in 2009 , infection control policies were intensified based on CF guidelines and surveillance data were collected and reviewed . - pubmed
CONCLUSIONS : Direct or indirect patient - to - patient transmission of M abscessus is a threat in the CF population . - pubmed
METHOD : Forty patients of apogeotropic HSC - BPPV colleted from March 2014 to May 2015 were divided into two groups , each group had 20 cases . - pubmed
AIMS : ( 1 ) To study the magnetic resonance imaging ( MRI ) brain findings in CPSs in children aged 1 - 18 years . - pubmed
METHODS : Hospital based prospective study in which MRI brain was done on all newly diagnosed children with complex partial seizures , aged 1 to 18 yrs , during the study period . - pubmed
RESULTS : Among the 64 children who were clinically diagnosed to have CPSs and subjected to MRI study of the brain , 40(62.5 % ) children were detected to have structural lesions , of which neurocysticercosis ( NCC ) was noted in 17 ( 42.5 % ) , tuberculoma in 12 ( 30 % ) , hippocampal sclerosis ( HS ) in 6 ( 15 % ) , gliosis in 4 ( 10 % ) , and tumor in 1 ( 2.5 % ) patient . - pubmed
RESULTS : All patients exhibited typical facial features and joint dislocations . - pubmed
CONCLUSIONS : All seven individuals with Larsen syndrome had a uniform clinical phenotype except for delayed carpal ossification in two of them . - pubmed
OBJECTIVE : To explore the genetic cause for a child featuring developmental delay and mental retardation . - pubmed
In patients with atherosclerotic complications of diabetes , impaired neovascularization of ischemic tissue in the myocardium and lower limb limits the ability of these tissues to compensate for poor perfusion . - pubmed
A study on the association of diabetic dermopathy with nephropathy and retinopathy in patients with type 2 diabetes mellitus . - pubmed
BACKGROUND : Diabetic dermopathy is one of the most prevalent skin complications in diabetes patients . - pubmed
Some studies have pointed to association of diabetic dermopathy with retinopathy and nephropathy in patients with type 2 diabetes as microangiopathy presentations , but no rigorous study has been conducted to confirm this association . - pubmed
OBJECTIVES : This study investigated association of diabetic dermopathy with nephropathy and retinopathy in patients with type 2 diabetes referring specialty clinic of Shahrekord . - pubmed
PATIENTS AND METHODS : This descriptive , cross - sectional study was conducted on 102 type 2 diabetes patients with dermopathy referring clinic constantly or as outpatient . - pubmed
Dermatological and ophthalmological examinations and examination for nephropathy were done for all patients . - pubmed
Prevalence of retinopathy in patients was 4.31 % and nephropathy 3.33 % . - pubmed
CONCLUSIONS : Results of this study confirm the association of diabetic dermopathy with retinopathy and nephropathy in patients with type 2 diabetes . - pubmed
Since dermopathy is usually developed before retinopathy and nephropathy , dermopathy could be used as a clinical finding in early diagnosis and prevention of retinopathy and nephropathy in diabetes patients . - pubmed
OBJECTIVE : This article investigates the prevalence and attributes of patients with open - angle glaucoma who exhibit improvement of visual field loss in a clinical setting . - pubmed
DESIGN : We conducted a retrospective chart review of patients in a clinical glaucoma practice . - pubmed
PARTICIPANTS : We identified 719 glaucoma patients with at least 5 SITA strategy visual field tests and a minimum continuous follow - up period of 5 years . - pubmed
Pathological , bacteriological , and molecular characteristics of natural outbreaks of Johne ' s disease in goats of Fars Province , Iran . - pubmed
The causative agent is an acid - fast bacterium , Mycobacterium avium paratuberculosis ( MAP ) . - pubmed
Duchenne muscular dystrophy ( DMD ) is a genetic neuromuscular disease that primarily affects young males . - pubmed
Recently a surge of new therapeutics for DMD is offering hope to patients . - pubmed
Palbociclib inhibits proliferation of human adrenocortical tumor cells . - pubmed
First Case of Skin and Soft Tissue Infection Caused by Mycoplasma hominis in a Pediatric Immunocompromised Patient . - pubmed
Patients with mild - to - moderate hypertriglyceridemia have an increased cardiovascular risk . - pubmed
Recently , new gene therapy approaches for LPL - deficient patients have become available in Germany . - pubmed
Bio - electric field enhancement : the influence on hyaluronan mediated motility receptors in human breast carcinoma . - pubmed
Here we show how a human breast carcinoma cell line was maintained in media prepared with a dilute saline solution that had been exposed to a dielectrophoretic ( DEP ) electromagnetic field ( EMF ) generated by 3 amperes of direct current ( dc ) to a device housing an array of conductive rings . - pubmed
Our studies showed a significant inhibition of growth of human breast carcinoma MDA - MB-231 cells when they were maintained in media prepared with dc - DEP EMF force treated dilute saline while no growth inhibition occurred when the same cells were maintained in identically prepared but untreated media . - pubmed
Also , mitotic spindle formation was inhibited in the human breast carcinoma when they were grown in dc - DEP EMF force treated media . - pubmed
To determine if any gene expression changes contributed to the selective growth inhibition and absent mitotic spindle formation in the human breast carcinoma grown in the treated media , we employed microarray analysis and found that there was large - scale transcriptional reprogramming of the tumor cells grown in the treated media with over 1,000 genes up- or down - regulated over 2 - fold , whereas the non - cancerous MCF-10A cells showed relatively modest changes in gene expression . - pubmed
In this study , we investigated the effects of dioscin ( DSN ) on human GBC and the potential mechanisms underlying these effects . - pubmed
Prosthetic Valve Infective Endocarditis With Mycobacterium Fortuitum : Antibiotics Alone Can Be Curative . - pubmed
RESULTS : Of the 69 patients , 25 had HeFH , 25 CVD , and 19 had both . - pubmed
CONCLUSION : In patients with HeFH and/or CVD , LDLC decreased from 115 to 68 mg / dl ( 39 % ) on ALI 75 mg with mean follow - up of 49 weeks , and from 165 to 70 mg / dl ( 59 % ) on ALI - EVO over 37 weeks , p & lt ; .0001 for both . - pubmed
Development and validation of a novel non - contact monitor of nocturnal respiration for identifying sleep - disordered breathing in patients with heart failure . - pubmed
Therefore , there is a need for simple and reliable validated methods to aid diagnosis in patients with HF . - pubmed
METHODS AND RESULTS : The study included 75 adult patients with systolic HF and suspected SDB who underwent simultaneous PSG and SM recordings . - pubmed
The SM algorithm had 70 % sensitivity and 89 % specificity for identifying patients with clinically significant SDB ( AHI & gt;= 15 / h ) . - pubmed
Transfer of altered behaviour and irritable bowel syndrome with diarrhea ( IBS - D ) through fecal microbiota transplant in mouse model indicates need for stricter donor screening criteria . - pubmed
In a local cohort study , patients had 72 % less neck pain ( visual analogue scale rating ) and 81 % less arm pain at 6 months when CESS was used as an isolated procedure , and 74 % less neck pain and 83 % less arm pain when coupled with disc replacement or fusion at an adjacent level . - pubmed
These cytotoxic lymphocytes suppress lung metastasis of A549 / A2.1 lung cancer cells in NSG mice . - pubmed
This approach should facilitate the development of cell - based immunotherapy for human lung cancer . - pubmed
Combined toxicity of microcystin - LR and copper on lettuce ( Lactuca sativa L. ) . - pubmed
The present study investigated the toxicity effects of microcystin - LR ( 0 , 5 , 50 , 500 , 1000 mug L-1 ) and copper ( 0 , 50 , 500 , 1000 , 2000 mug L-1 ) , both individually and in mixture , on the germination , growth and oxidative response of lettuce . - pubmed
Our results suggest that the toxicity effects of microcystin - LR and copper are exacerbated when they co - exist in the natural environment at low concentrations , which not only negatively affects plant growth but also poses a potential risk to human health via the food chain . - pubmed
MATERIALS AND METHODS : One hundred and thirty - three Mexican climacteric women with moderate - to - severe depression enrolled in the HOMDEP - MENOP Study ( a randomized , placebo - controlled , double - blind , double - dummy , three - arm trial , with a 6 - week follow - up study ) were evaluated . - pubmed
Polyphenolic Composition of Lentil Roots in Response to Infection by Aphanomyces euteiches . - pubmed
Genotype , infection and their interaction determined the composition of polyphenols in lentil roots . - pubmed
Infection increased the concentration of kaempferol , apigenin , and naringenin in the root tissues of all genotypes , but had no effect on some polyphenols in the low - tannin genotype L. - pubmed
This study shows that genotypic differences exist in the composition of root polyphenols in lentil , and is related to the response to infection caused by A. - pubmed
Polyphenols , particularly the organic acid content could be useful for selection and breeding of lentil genotypes that are resistant to Aphanomyces root rot ( ARR ) disease . - pubmed
BACKGROUND : Resection of pulmonary metastases is an important treatment option for patients with oligometastatic melanoma . - pubmed
Here , we report outcomes of a registry - based study of patients who underwent lung resection for cutaneous melanoma metastases . - pubmed
RESULTS : Ninety - nine patients underwent resection of cutaneous melanoma lung metastases . - pubmed
CONCLUSIONS : In this unselected population - based study , 21 % of patients were 5 - year survivors after pulmonary metastasectomy for melanoma . - pubmed
A 75 - year - old man with a history of mechanical aortic valve replacement with aortic conduit for severe aortic insufficiency underwent routine screening computed tomography evaluation revealing right coronary anastomosis endoleak and proximal aortic root pseudoaneurysm . - pubmed
Short- and long - term outcomes of laparoscopic hepatectomy in elderly patients with hepatocellular carcinoma . - pubmed
PURPOSE : To compare short- and long - term outcomes of laparoscopic hepatectomy ( LH ) in elderly and non - elderly patients with hepatocellular carcinoma ( HCC ) . - pubmed
METHODS : Clinical and follow - up data of patients with HCC who underwent LH in our Institute from January 2011 to December 2016 were retrospectively analyzed . - pubmed
RESULTS : The Charlson comorbidity index and American Society of Anesthesiologists ( ASA ) score of patients in the elderly group were higher than those of patients in the nonelderly group , and the rates of hepatitis virus infection and cirrhosis in the elderly group were lower than those in the non - elderly group . - pubmed
Old age is not a contraindication for LH in patients with HCC . - pubmed
METHODS : This institutional review board - approved prospective double - blinded trial involved 111 patients with adolescent idiopathic scoliosis who were randomized to receive either a placebo or TXA ( 50 - mg / kg loading dose and 10 - mg / kg / h infusion ) . - pubmed
Power analysis indicated that 50 patients per group would provide power to detect a & gt;20 % difference in blood loss . - pubmed
CONCLUSIONS : Use of TXA in patients undergoing surgery for adolescent idiopathic scoliosis significantly reduced blood loss , by 27 % , compared with that in the placebo group . - pubmed
Patients with greater intraoperative blood loss spent a longer time in the hospital . - pubmed
METHODS : 40 patients between 3 to 18 years of age , with clinical diagnosis of acute rheumatic fever or new activity in established rheumatic heart disease were included . - pubmed
Effects of omega-6 / 3 and omega-9/6 nutraceuticals on pain and fertility in peritoneal endometriosis in rats . - pubmed
MATERIALS AND METHODS : Study analyses the 244 ECG indices in 111 patients ( 79 males and 32 females , age 53 + -17 years ) with RBBB tachycardias , who underwent electrophysiological studies . - pubmed
First step includes retrospective analysis of QRS characteristics in 20 patients with ventricular tachycardias ( VT ) , 24 pts with aberrant supraventricular tachycardias ( SVT+RBBB ) and 14 pts with antidromic SVTs ( WPW ) . - pubmed
The prognostic accuracy of the algorithms was subsequently evaluated on a prospective group of patients with RBBB tachycardias ( n=53 ) . - pubmed
The ITP working group of the Spanish Society of Paediatric Haematology and Oncology has updated its guidelines for diagnosis and treatment of primary immune thrombocytopenia in children , based on current guidelines , bibliographic review , clinical assays , and member consensus . - pubmed
Nephrotoxicity of amikacin in noncritically ill patients : . - pubmed
AIMS : Several studies have reported that critically ill patients who require amikacin for the treatment of severe infection require therapeutic drug monitoring ( TDM ) to prevent acute kidney injury . - pubmed
Therefore , the aim of this study was to investigate the nephrotoxicity and tolerability of amikacin in noncritically ill patients . - pubmed
However , an increasing trend of AKI risk was observed in patients with low baseline estimated glomerular filtration rate . - pubmed
CONCLUSION : In noncritically ill patients , the incidence of amikacin - induced nephrotoxicity was lower than that reported in previous studies . - pubmed
Methods : Eighteen patients with N2O abuse or vitamin B12 deficiency were recruited . - pubmed
Conclusion : Compared to vitamin B12 deficiency , N2O abuse patients showed prominent motor superexcitability changes and less prominent sensory superexcitability changes , hinting a unique pathological process different from that of vitamin B12 deficiency . - pubmed
RESULTS : In 2891 men and 4002 women aged 50 - 79 years , 1099 non - vertebral osteoporotic fractures - including 393 hip fractures - were sustained during the median 15 years follow - up . - pubmed
Rapid Proteome Changes in Plasma and Cerebrospinal Fluid Following Bacterial Infection in Preterm Newborn Pigs . - pubmed
Feeding bovine colostrum reduced the sepsis - related changes in clinical indices and plasma proteins . - pubmed
Conclusion : Systemic infection with SE induces inflammation with rapid proteome changes in the plasma and CSF in preterm newborn pigs . - pubmed
The observed early markers of sepsis and neuroinflammation in preterm pigs may serve as novel biomarkers for sepsis in preterm infants . - pubmed
Methods : In vivo , different concentrations of aloin were intraperitoneally injected 1 h before the establishment of the HIR model in male mice . - pubmed
In vitro , aloin ( AL , C21H22O9 ) or lipopolysaccharide ( LPS ) was added to a culture of mouse primary hepatocytes before it underwent hypoxia / reoxygenation ( H / R ) , and the apoptosis in the mouse primary hepatocytes was analyzed . - pubmed
Values of intravoxel incoherent motion diffusion weighted imaging and dynamic contrast - enhanced MRI in evaluating the activity of sacroiliitis in ankylosing spondylitis of rat model . - pubmed
OBJECTIVE : To prospectively evaluate the ability of IVIM - DWI and DCE - MRI in detecting early activity of sacroiliitis in rat model of ankylosing spondylitis by comparing with pathological results . - pubmed
Chronic Oral Palmitoylethanolamide Administration Rescues Cognitive Deficit and Reduces Neuroinflammation , Oxidative Stress , and Glutamate Levels in A Transgenic Murine Model of Alzheimer ' s Disease . - pubmed
In this study , we evaluated the neuroprotective and antioxidant effects of chronic ( three months ) um - PEA administration in an animal model of AD ( 3xTg - AD mice ) . - pubmed
The chronic treatment with um - PEA ( 100 mg / kg / day for three months ) rescued cognitive deficit , restrained neuroinflammation and oxidative stress , and reduced the increase in hippocampal glutamate levels observed in 3xTg - AD mice . - pubmed
Overall , these data reinforce the concept that um - PEA exerts beneficial effects in 3xTg - AD mice . - pubmed
Icariin is a main component of the Chinese medicinal plant Epimedium brevicornu Maxim , exhibits potent activity against inflammatory diseases . - pubmed
Herein , we investigated the effects of icariin on primary cultured fetal rat hippocampal neurons and OVALPS - OVA induced asthma rat model . - pubmed
A novel actinomycete , designated strain NEAU - C151 T , was isolated from soil collected from Mount Song and characterized using a polyphasic approach . - pubmed
The type strain is NEAU - C151 T (= CGMCC 4.7498T = DSM 107808 T ) . - pubmed
PURPOSE : To evaluate the outcome of robot - assisted residual mass resection ( RA - RMR ) in nonseminomatous germ cell tumor ( NSGCT ) patients with residual tumor following chemotherapy . - pubmed
Patients were considered for RA - RMR in case of a residual tumor between 10 and 50 mm at cross - sectional computed tomography ( CT ) imaging located ventrally or laterally from the aorta or vena cava , with normalized tumor markers following completion of chemotherapy , and no history of retroperitoneal surgery . - pubmed
Histopathology showed teratoma , necrosis and viable cancer in 29 ( 64.4 % ) , 14 ( 31.1 % ) , and two patients ( 4.4 % ) , respectively . - pubmed
This neurological disorder has been previously reported in bone marrow transplant recipients but is uncommon after kidney transplantation . - pubmed
CASE PRESENTATION : In this report , we present a case of a 47 - year - old male patient 12 years after his second kidney transplantation who developed GBS due to papillary renal cell carcinoma . - pubmed
CONCLUSIONS : In kidney transplant recipients , paraneoplastic aetiology should be considered in the differential diagnosis of GBS . - pubmed
Cardiac manifestations and effects of enzyme replacement therapy for over 10 years in adults with the attenuated form of mucopolysaccharidosis type I. - pubmed
There have been only a few reports on the effect of long - term enzyme replacement therapy ( ERT ) for adult patients with the attenuated form of MPS I ( Scheie syndrome ) and cardiac involvement . - pubmed
Methods : We retrospectively reviewed four adult patients of Scheie syndrome for which ERT was performed in our hospital . - pubmed
We investigated the findings of electrocardiography and echocardiography for the four patients performed before and 10 years after the initiation of ERT to evaluate the efficacy for ERT in Scheie syndrome . - pubmed
One patient had gradual progressive aortic valve stenosis and mitral valve stenosis during the course of ERT , and double valve replacement was finally performed . - pubmed
The patient who had started ERT at the youngest age did not develop significant cardiovascular disease . - pubmed
Regarding clinical courses with ERT for a period of 10 years , all four patients survived and they showed relatively stable cardiac conditions although two patients developed sick sinus syndrome after the valvular surgery . - pubmed
Conclusions : Valvular disease in patients with Scheie syndrome occur at a young age . - pubmed
OBJECTIVES : To analyse the diagnostic performance of eosinopenia , alone or combined with polymorphonuclear neutrophils ( PMN ) and/or lymphocytes , as a marker of active COVID-19 in patients hospitalized for suspicion of SARS - CoV-2 infection . - pubmed
RESULTS : One - hundred and twenty - one patient were included : 57 patients were diagnosed with COVID-19 , 64 patients were not . - pubmed
CONCLUSION : Eosinopenia - < 10 / muL - and eosinophil / PMN ratio are useful , low - cost , reproducible tools to help diagnose COVID-19 , during an epidemic period , in a population of hospitalized patients admitted for suspicion of COVID-19 . - pubmed
Needle electromyography of craniobulbar muscles in patients with amyotrophic lateral sclerosis : Direct comparison between genioglossus and masseter muscles . - pubmed
Three main variants are described in males : adrenomyeloneuropathy ( AMN ) , a cerebral form ( cALD or cAMN ) and Addison ' s disease only ( AD ) , while for females no classification is used . - pubmed
To evaluate pain and the functional state of afferent fibers , a series of tests was carried out in male and female patients . - pubmed
METHODS : Chronic pain occurrence and sensory phenotype profile were assessed in 30 patients ( 20 male : 10 AMN , 1 cAMN , 1 cALD , 8 AD ; and 10 female ) . - pubmed
Male AMN / cAMN / cALD patients showed the worst impairment . - pubmed
Cardiovascular complications in COVID-19 patients with or without diabetes mellitus . - pubmed
Multivariate logistic regression was used to estimate the adjusted odds ratio for the study outcomes in DM patients , compared to those without DM , stratified by age , sex and glycaemic control . - pubmed
The unadjusted rates were higher in DM patients compared to non - diabetics for the composite cardiovascular end - point ( 73.2 % vs. 40.6 % p < .0001 ) , acute myocarditis ( 36.6 % vs. 15.5 % p = .004 ) , acute heart failure ( 25.3 % vs. 5.6 % p = .001 ) , acute myocardial infarction ( 9.9 % vs. 1.4 % p = .03 ) and new - onset atrial fibrillation ( 12.7 % vs. 1.4 % p = .009 ) . - pubmed
After controlling for relevant confounding variables , diabetic patients had higher odds of composite cardiovascular end - point , acute heart failure and new - onset atrial fibrillation . - pubmed
A 30 - year - old male patient presented with history of haemoptysis associated with cyanosis and clubbing . - pubmed
This low molecular weight protein is found in the urine of some patients with renal tubular disorders , but some workers have emphasized its importance as a causal agent in hypokalaemia of acute myeloid leukaemia . - pubmed
The patients selected for treatment have presented chondrosarcoma ( ten ) , so - called benign giant - cell tumour of bone , usually recurrent ( nine ) , angiomatous osteolysis ( two ) , seemingly single thyroid or renal metastasis ( two ) , and ununited pathological fracture after irradiation of a tumour ( one ) . - pubmed
Tryptophan metabolism and recurrence rates of patients with breast cancer after mastectomy . - pubmed
Women with early breast cancer were given a loading dose of L - tryptophan after mastectomy and a comparison made between their excretion of metabolites of the kynurenine pathway and the rate of recurrence of the disease . - pubmed
Fecapentaene excretion and fecal mutagenicity in relation to nutrient intake and fecal parameters in humans on omnivorous and vegetarian diets . - pubmed
Fecapentaenes are strong fecal mutagenic compounds presumably occurring in the majority of Western human individuals , and are possibly essential initiators of colon carcinogenesis . - pubmed
Since vegetarians at low risk for colorectal cancer excrete higher concentrations of fecapentaenes , it could be hypothesized that relatively increased fecapentaene excretion in combination with antimutagenic compounds in feces represents colon cancer prevention . - pubmed
Pretreatment patients showed significantly higher ratio of complete remission than relapsed patients , and mean value of IC50 for adriamycin in initial presentation was higher than at relapse . - pubmed
[ Renal protection in diabetic patients with ACE inhibitors ] . - pubmed
[ Clinico - immunomorphological characteristics of the mucosa of the distal segments of the large intestine in children with gastroduodenitis ] . - pubmed
The clinical , x - ray , endoscopic and morphological studies performed in 156 children afflicted with gastroduodenitis have shown that concomitant lesions of the colon are of paramount importance in the genesis of this illness . - pubmed
In vivo administration of bromodeoxyuridine and flow cytometry for cell kinetic studies in human malignancies . - pubmed
[ Results of drug sensitivity test of UFT , doxorubicin and cisplatin using human urogenital cancers transplanted subcutaneously into nude mice ] . - pubmed
Experimental chemotherapy with UFT , doxorubicin and cisplatin was performed against human urogenital cancers transplanted subcutaneously into nude mice . - pubmed
The tumor take was confirmed in 33 cell lines of human neoplasms which consisted of 10 renal cell carcinomas , 5 renal pelvic carcinomas , 3 ureteral carcinomas , 8 carcinomas of the urinary bladder , 3 prostatic carcinomas and 4 testicular tumors . - pubmed
Amongst adults exposed to the hepatitis B virus ( HBV ) , the infection pursues a fulminant course more frequently in females , while conversely a chronic carrier state is more frequent in males . - pubmed
That this was not a nonspecific effect of fulminant hepatitis was confirmed by the significantly higher levels in this group than in age - matched females with fulminant hepatitis unrelated to HBV ( P less than .05 ) . - pubmed
An intimal sarcoma of the abdominal aorta in a 63 - year - old woman is reported . - pubmed
Noradrenaline acutely ( 30 min ) increased BAT mitochondrial GDP binding of lean and obese Zucker rats , without any change in uncoupling - protein concentrations . - pubmed
[ Pyridoxal and pyridoxamine phosphate levels in the plasma and bone marrow of children with acute leukemia ] . - pubmed
Twenty - six patients with idiopathic Raynaud ' s phenomenon participated in a double - blind , crossover clinical trial comparing the clinical effect of nifedipine with that of placebo . - pubmed
From 1977 to 1985 , 22 patients less than 4 years of age ( mean age 18.2 months ) underwent direct aortic reimplantation of the anomalous left coronary artery . - pubmed
Moderate to severe preoperative mitral incompetence lessened in all patients but one , without mitral valve repair . - pubmed
Infants with severely impaired left ventricular function and persistent congestive heart failure should probably undergo operation as soon as the diagnosis has been made . - pubmed
Since 1980 , 112 patients presenting with tumours of the eyelid were treated by cryotherapy at the First University Department of Ophthalmology in Vienna . - pubmed
Tumour recurrence existed in 29 of these patients who had previously undergone surgical treatment or radiotherapy . - pubmed
Within a follow - up period of 5 years , 9 % of the patients with basal cell epithelioma and spindle cell epithelioma experienced recidivation . - pubmed
All 6 infected monkeys developed primary and satellite cutaneous leishmanial lesions which were measured for up to 30 weeks in 3 of the monkeys and up to 52 weeks in the other 3 monkeys . - pubmed
Two owl monkeys which had recovered from cutaneous leishmaniasis demonstrated acquired resistance when challenged with an intradermal inoculation of L. - pubmed
b. panamensis were similar in many respects to those observed in humans with localized cutaneous leishmaniasis . - pubmed
Oncogenic transformation of hamster embryo cells after exposure to inactivated herpes simplex virus type 1 . - pubmed
The in vitro transformation of hamster embryo fibroblasts by herpes simplex virus type 1 ( HSV-1 ) after exposure of the virus to UV irradiation is described . - pubmed
Cell transformation was induced by 2 out of 12 strains of HSV-1 that were tested for transforming potential . - pubmed
Cells transformed by the KOS strain of HSV-1 were not oncogenic when injected into newborn Syrian hamsters . - pubmed
However , cells transformed by HSV-1 strain 14 - 012 induced tumors in 47 % of the newborn hamsters injected . - pubmed
Immunopathology and microvascular lesions in human sympathetic ganglia . - pubmed
Lumbar sympathetic ganglia surgically removed from adult patients affected by obstructive peripheral arteriopathies are investigated with traditional histology and fluorescent antibody technique . - pubmed
Patients with disorders of hemostasis who undergo surgical procedures are in danger of hemorrhage . - pubmed
In three patients with coagulopathy - one with mild classical hemophilia , one with Christmas disease , and one with warfarin toxicity - the abnormality was missed by routine preoperative history but promptly detected by the routine preoperative use of the activated coagulation time ( act ) . - pubmed
Effect of dopamine on pentagastrin - stimulated gastric antral motility in dogs with gastric fistula . - pubmed
The purpose of the present study was to evaluate the effect of dopamine on gastric antral motility in conscious dogs with gastric fistula by using miniature strain - gauge transducers . - pubmed
A comparative study of the diagnosis value of drug - induced sleep EEGs and sleep EEGs following sleep deprivation in patients with complex partial seizures . - pubmed
On the following day a sleep EEG of the same patient was recorded after sleep deprivation of 24 - -26 h. If only patients whose wake EEGs were free from epileptic activity are considered , the rate of provocation was 58 % . - pubmed
For practical purposes it is recommended that for those patients whose wake EEGs are free from epileptic activity , a sleep EEG -- possibly drug - induced -- should be recorded . - pubmed
Central and peripheral cardiovascular actions of urapidil in normotensive and Goldblatt hypertensive animals . - pubmed
The central effect of urapidil on mean arterial blood pressure , heart rate , and reflex tachycardia was studied in anesthetized normotensive and Goldblatt hypertensive dogs and anesthetized cats . - pubmed
Complications were few ; drowsiness occurred in 9 % , dizziness was troublesome in one patient , but there was no nausea or vomiting and no one became unconscious . - pubmed
Peak plasma levels of 177 and 270 micrograms / ml were reached 1 h after the initial injection and therapeutic levels persisted for at least 12 h. This initial study indicated that a suggested dose regime in snakes , derived by extrapolation from mammalian dosages , of 100 - 125 mg / kg daily was insufficient to produce plasma levels of sufficient magnitude and duration to effectively treat Pseudomonas infections in snakes . - pubmed
The electrophysiologic effects of intravenous verapamil and propranolol were compared alone and in combination in 14 patients ( aged 21 to 69 years ) with paroxysmal supraventricular tachycardia ( SVT ) . - pubmed
Ten patients had atrioventricular ( AV ) reentry utilizing a manifest ( 7 patients ) or concealed ( 3 patients ) accessory pathway . - pubmed
Verapamil or propranolol prevented SVT induction in 7 patients ( 50 % ) . - pubmed
However , only the drug combination prevented reinduction of sustained SVT in 6 patients . - pubmed
These 6 patients were treated chronically with verapamil and propranolol , with no recurrence of SVT in any patient after 2 to 26 months . - pubmed
Acetaminophen metabolism and clearance after a single 1 gm oral dose of the drug was investigated in 12 healthy men , six of whom were cigarette smokers , and in six men who were receiving anticonvulsant drugs for epilepsy . - pubmed
In contrast , sulfinpyrazone pretreatment increased ClAP by 23 % ( from 5.70 + /- 0.21 to 7.00 + /- 0.39 ml / min / kg ) and ClAP was 46 % greater in the epileptic subjects who received anticonvulsant drugs than in the control group ( 8.32 + /- 0.45 and 5.70 + /- 0.21 ml / ml / kg ) . - pubmed
In order to elucidate the still controversial question whether iron foreign bodies located in the orbit can produce siderosis bulbi , the authors studied the concentration of iron in the aqueous of rabbits in which the metal was placed outside the eyeball , close to the exposed sclera . - pubmed
Relation of antibody - coated urine bacteria to the site(s ) of infection in experimental dogs . - pubmed
It was concluded that the antibody - coated bacteria test does not provide accurate information to support the diagnosis of pyelonephritis in the dog . - pubmed
Antibodies to antigens presumably associated with Hodgkin 's ( HD ) and antigens associated with HD and Non - Hodgkin lymphomas ( NHL ) have been isolated by an immunosorbent procedure using serum of an untreated patient with HD and his affected splenic tissue immobilized in polyacrylamide gel . - pubmed
The inflammatory cell composition of pleural or ascitic effusion fluids from 13 patients with malignant disease and 8 patients with benign disease was analyzed . - pubmed
The smallpox story : man finally defeats an old adversary . - pubmed
For this reason immediate surgical decompression ( including the meatal foramen ) was performed on 14 patients with 90 % or more degeneration within three weeks of palsy onset . - pubmed
Overloading of the highest nervous activity induced no hypertension in these animals , though the self - stimulation frequency increased . - pubmed
Renal artery constriction resulted in a fast and large increase in blood pressure in comparison with that of control rats . - pubmed
We think that the possibility of this anatomic arrangement should always be considered in patients with isolated aortic coarctation whose clinical condition seems impaired rather than improved after an apparently successful coarctectomy . - pubmed
RESULTS : At admission , 12 patients were comatose ( Glasgow Coma Scale & lt ; 10 ) , 7 had generalized convulsions . - pubmed
Four patients died during the study , 3 from multiple organ failure . - pubmed
The chromosome aberration frequency in murine somatic cells was studied . - pubmed
In 4 years we performed primary reconstruction of cloacal anomalies in 4 children , 3 of whom had hydrocolpos and 1 vaginal agenesis . - pubmed
Distal vaginal occlusion related to ischemia occurred in 2 patients and in both the vagina was successfully reconstructed at a second stage procedure . - pubmed
OBJECTIVES : This study attempted to determine the incidence , prognosis and predictability of postoperative left ventricular dysfunction in patients undergoing correction of mitral regurgitation . - pubmed
BACKGROUND : Left ventricular function in patients with mitral regurgitation is altered by loading conditions and is difficult to assess . - pubmed
METHODS : In 266 patients undergoing correction of mitral regurgitation between 1980 and 1989 , left ventricular function was echocardiographically assessed preoperatively ( within 6 months ) and postoperatively ( within 1 year ) . - pubmed
Postoperative left ventricular dysfunction ( ejection fraction & lt ; 50 % ) was frequent ( 41 % of patients ) and carried a poor prognosis ( at 8 years survival , 38 % + /- 9 % vs. 69 % + /- 8 % , p & lt ; 0.0001 ) . - pubmed
Gliomatosis peritonei ( GP ) is the implantation of glial tissue on the peritoneal surface in patients with solid ovarian teratoma . - pubmed
Early parenteral nutrition in patients unconscious because of acute drug poisoning . - pubmed
The author studied the clinical and laboratory effects of early parenteral nutrition ( EPN ) in patients who were comatose as a result of acute drug poisoning . - pubmed
These results suggest that although the pharmacokinetic profiles of losartan and E-3174 do not change during repeated administration , the blood pressure lowering effect in hypertensive patients is greater after multiple doses than after a single dose . - pubmed
To our knowledge concomitant avulsion fractures in this condition have not been reported thus far in pediatric patients . - pubmed
Vagal activation in novelty - induced tachycardia during the light phase in the rat . - pubmed
The CD4 + T - cell clones developed against SLA class II - negative PAECs recognized strain - specific porcine xenoantigens indirectly . - pubmed
Thresholds were measured at implant , predischarge , and at a mean follow - up of 50 days in 46 patients with a uniform testing protocol and shock polarity . - pubmed
CLINICAL CASE : We present the case of a man with cutaneous lesions compatible with the diagnosis of neurocutaneous melanosis since birth , with benign self - limiting epilepsy in early childhood . - pubmed
MR should be done periodically in patients with cutaneous lesions suggestive of this condition . - pubmed
In conclusion , inhaled NO , given with a high FiO2 , in the presence of this established endotoxinic lung injury did not reverse the markers of PMN activation studied nor lung edema formation in this rat model . - pubmed
Accordingly , human cancers and some premalignant lesions contain multiple genetic abnormalities not present in the normal tissues from which the neoplasms arose . - pubmed
Varicocele repair improves semen parameters in azoospermic men with spermatogenic failure . - pubmed
PURPOSE : We analyzed the efficacy of varicocele repair in improving semen parameters in azoospermic men with spermatogenic failure . - pubmed
MATERIALS AND METHODS : After routine clinical evaluation with confirmatory pellet analysis testicular biopsy and varicocele repair were simultaneously performed in 28 azoospermic men with a primary diagnosis of unilateral or bilateral varicocele and spermatogenic failure . - pubmed
Only 9 men with severe hypospermatogenesis and 5 with maturation arrest spermatid stage had improvement in sperm density . - pubmed
The reduction in local recurrences seen in patients with head and neck cancer following radiotherapy led to coining of the term " subclinical disease " to describe the presumed presence of small , clinically undetectable , nests of tumor cells which remain even after the most aggressive of surgeries . - pubmed
Peculiarities of modifications of errors made by human subjects in identification of masked visual images within the " fatigue -- negative emotions " range were investigated . - pubmed
Detection of sialic acids and gangliosides with special reference to 9 - O - acetylated species in basaliomas and normal human skin . - pubmed
UNLABELLED : In addition to patients with coronary artery disease , high - risk patients with severe congestive heart failure can benefit from rehabilitation . - pubmed
This review explores these beneficial outcomes through an assessment of therapeutic approaches , with special emphasis on the unique clinical characteristics of patients with congestive heart failure . - pubmed
OVERALL ARTICLE OBJECTIVE : To describe the benefits and the evolving role of cardiac rehabilitation for patients with congestive heart failure . - pubmed
A case is reported of a young woman who , within a 2 - year period , was diagnosed with an osteoblastoma at the apex of a maxillary molar and with a plexiform unicystic ameloblastoma in the posterior mandible . - pubmed
Rational therapy of chronic venous insufficiency -- chances and limits of the therapeutic use of horse - chestnut seeds extract . - pubmed
BACKGROUND AND METHODS : We report two clinical studies , one already published , performed in patients with early and advanced chronic venous insufficiency ( CVI ) . - pubmed
Nylon membranes with two spots of UV - immobilized primer pairs -- one for BVDV and one for BHV -- were used in amplification with both corresponding templates , with each template singly and with no template . - pubmed
Effects of L - arginine on blood pressure and metabolic changes in fructose - hypertensive rats . - pubmed
Our data also suggest a strong relationship between hyperinsulinemia and hypertension in this hypertensive rat model . - pubmed
Central nervous system relapse in adults with acute lymphoblastic leukemia . - pubmed
BACKGROUND : Recurrence of acute lymphoblastic leukemia ( ALL ) in the central nervous system ( CNS ) in adults is considered a poor prognostic feature . - pubmed
The objective of this study was to analyze the experience with CNS recurrence in adult patients with ALL . - pubmed
METHODS : Between December 1982 and April 2000 , the records of 527 consecutive , newly diagnosed patients with ALL who were treated at the M. D. Anderson Cancer Center were reviewed . - pubmed
All patients had received CNS prophylaxis tailored to the risk of CNS recurrence with systemic chemotherapy with or without intrathecal ( IT ) chemotherapy ; none received cranial radiotherapy for prophylaxis . - pubmed
Three groups were identified : 1 ) patients with an isolated CNS recurrence ( n = 17 patients ) , 2 ) patients with CNS recurrences after bone marrow ( BM ) recurrence ( n = 8 patients ) , and 3 ) patients with simultaneous CNS and BM recurrences ( n = 7 patients ) . - pubmed
The median survival from CNS recurrence was 6 months ; 28 % of patients were alive at 1 year , and 6 % of patients were alive at 4 years . - pubmed
CONCLUSIONS : Adults with ALL and CNS recurrences have a poor prognosis despite effective IT chemotherapy . - pubmed
Effective CNS prophylaxis remains the single best approach for treating patients with CNS leukemia . - pubmed
Their anti - fungal activity against Pyricularia oryzae and cytotoxic activity on K562 and HCT-15 cell lines were evaluated in vitro . - pubmed
LDL receptor - deficient male mice were randomly divided into 4 groups ( n = 11 each ) . - pubmed
The diabetic and the nondiabetic mice were sacrificed after 3 and 5 weeks , respectively . - pubmed
The atherosclerotic plaque area was significantly smaller in the omapatrilat - treated mice , both diabetic and nondiabetic , as compared to nontreated controls . - pubmed
In the diabetic animals , the plaque area was 8887 + /- 5386 microm2 and 23220 + /- 10400 microm2 , respectively for treated and nontreated mice ( P = .001 ) . - pubmed
Plasma lipids were increased by omapatrilat : Mean plasma cholesterol in treated mice , diabetic and nondiabetic combined , was 39.31 + /- 6.00 mmol / L , versus 33.12 + /- 7.64 mmol / L in the nontreated animals ( P = .008 ) . - pubmed
We performed a pilot study of breath VOCs , a potential new marker of disease in women with breast cancer . - pubmed
This was a combined case - control and cross - sectional study of women with abnormal mammograms scheduled for a breast biopsy . - pubmed
[ Treatment of schizophrenia in children ] . - pubmed
[ Food poisoning caused by Salmonella enteriditis & amp ; Escherichia coli 055 B5 ] . - pubmed
Antimicrobial activity of penicillin V and phenethicillin with special reference to organisms isolated from 17 patients with subacute bacterial endocarditis . - pubmed
Development of mast cell reaction during chemical skin carcinogenesis of mouse . - pubmed
Epidemiological and bacteriological features of infections associated with an organism related to Salmonella paratyphi B. - pubmed
Nicotine is not clastogenic at doses of 1 or 2 mg / kg body weight given orally to male mice . - pubmed
These data contradict the only published in vivo study of nicotine in which 1.1mg / kg bw was called positive for the induction of chromosomal aberrations in mouse bone marrow cells at all sampling intervals , even as early as 6h after treatment . - pubmed
Evidence of subtle auditory deficit in a group of patients recovered from bacterial meningitis . - pubmed
OBJECTIVES : Sensorineural hearing loss of greater than 30 dB hearing loss occurs in up to 30 % of patients after acute bacterial meningitis . - pubmed
This study investigated whether postbacterial meningitic patients with no apparent clinical sensorineural hearing loss had any evidence of more subtle subclinical cochlear deficit . - pubmed
PATIENTS : Fifty - eight controls and 20 postbacterial meningitic patients aged between 18 and 38 years were screened by a questionnaire and tympanometry to exclude hearing loss attributable to other causes . - pubmed
RESULTS : Mean thresholds over the range of standard pure - tone audiometry ( analyzed independently ) for the postbacterial meningitic patients were significantly elevated at most frequencies ( p & lt ; 0.05 - p & lt ; 0.001 ) between 4 and 7 dB in both ears above control group values . - pubmed
CONCLUSIONS : Postbacterial meningitic patients with hearing below the 90th percentile range had a slight but significant subclinical threshold elevation over the standard pure - tone audiometry . - pubmed
Two patients with dural sinus thrombosis and rapidly deteriorating levels of consciousness underwent unsuccessful attempts at mechanical thrombolysis via the usual transfemoral route . - pubmed
Individuals with schizophrenia are know to demonstrate cognitive and behavioral difficulties , particularly alterations in executive functions , including working memory . - pubmed
It is unclear whether these deficits reflect trait - related vulnerability to schizophrenia indicators and can be assessed by studying nonpsychotic relatives of patients with schizophrenia . - pubmed
In this study , we used an oculomotor delayed response ( ODR ) paradigm to examine spatial working memory in 37 " high - risk " child and adolescent offspring and siblings ( age range=6 - 25 years ) of patients with schizophrenia or schizoaffective disorder . - pubmed
The influence of anatomical variations in patients with left dominant circulation on coronary arteriosclerosis is not clear . - pubmed
METHODS : We examined 139 patients with polyp using colonoscopy and mucosal staining , and observed the pit patterns ( proposed by Kudo ) with magnifying endoscope and stereomicroscope to identify the relations between the pit patterns and the pathologic diagnosis . - pubmed
RESULTS : Polyps were identified in 124 patients and advanced cancers in 9 . - pubmed
It is essential therefore to be able to estimate an individual patient 's risk of harboring clinically silent micrometastatic disease using established prognostic factors . - pubmed
It is standard practice to administer systemic therapy to all patients with lymph node - positive disease . - pubmed
A new guidance device facilitates percutaneous puncture of the foramen ovale in human cadavers . - pubmed
CONCLUSION : The employment of a guidance device facilitated percutaneous transforaminal puncture and resulted in a significantly decreased number of puncture attempts as compared to free - hand techniques in human cadavers . - pubmed
Even though central nervous system disturbances occurred more frequently among efavirenz - treated patients and nonclinically significant transaminitis occurred more frequently among nevirapine - treated patients , these adverse events were not statistically significant or mutually exclusive . - pubmed
We designed this study to examine whether postanesthesia learning impairment is persistent in young rats . - pubmed
Hence , in adult rats , previous general anesthesia is not associated with impaired learning 2 wk later . - pubmed
One patient complained of pain during removal of a spacer . - pubmed
In the presented case , only the patient 's clinical course and duplex sonography , which showed bilateral cervical arterial dissections , led to the diagnosis of aortic dissection . - pubmed
This case emphasizes that early ultrasound examination is crucial in patients with suspected cerebral ischemia . - pubmed
In this report we describe a 16 - month - old boy who presented with aplastic anaemia preceding a non - A , non - B , non - C fulminant liver failure . - pubmed
These patients also need to be evaluated extensively in order to exclude a primary immunodeficiency . - pubmed
Anxiety - like behavior of young rats after 2 - week zinc deprivation . - pubmed
In the plus - maze test , the time spent in the open arms was also decreased in zinc - deficient rats , suggesting that anxiety - like behavior is increased in zinc deficiency . - pubmed
Nine patients with carotid body tumors were identified , three of them with complicated diagnosis . - pubmed
MATERIAL AND METHODS : Severe CAP in patients ( n = 103 , aged 18 - 60 years , male 89 % ) were randomly subdivided into the 4 comparable groups . - pubmed
[ Thermal therapy for patients with chronic heart failure ] . - pubmed
Crude extracts of Euchresta formosana radix inhibit invasion and migration of human hepatocellular carcinoma cells . - pubmed
Frontal lobe dysfunction in children with temporal lobe epilepsy . - pubmed
There is evidence that adults with temporal lobe epilepsy present executive impairments . - pubmed
We aimed to : 1 ) investigate the presence and severity of executive dysfunctions in children with temporal lobe epilepsy , and 2 ) determine the implications of clinical variables ( including etiology ) in the occurrence and severity of executive dysfunction , using eight paradigms . - pubmed
Thirty - one children with temporal lobe epilepsy were evaluated and compared with 21 age - matched controls . - pubmed
Patients with temporal lobe epilepsy had significantly worse performance than controls . - pubmed
Intragroup analysis indicated that patients with symptomatic epilepsy were more impaired than those with cryptogenic epilepsy . - pubmed
In the former group , patients with mesial lesions performed worse than those with lateral lesions . - pubmed
These findings indicated the presence of frontal lobe dysfunction in children with temporal lobe epilepsy , with worse performance in those with mesial temporal lobe epilepsy , early onset , longer duration of disease , and use of polytherapy . - pubmed
Influenza virosomes are an efficient antigen carrier and adjuvant system that are approved for the use in human vaccines . - pubmed
Among 65 patients who underwent surgery for choledochal cyst between March 1995 and June 2005 , we selected 34 adult patients who were diagnosed as having choledochal cyst . - pubmed
Of the 34 patients , excision of choledochal cyst and hepaticojejunostomy were done in 33 patients , and 1 patient with chronic pancreatitis underwent pylorus - preserving pancreaticoduodenectomy . - pubmed
Anastomotic stricture and intrahepatic duct stones postoperatively developed in eight patients ; one patient of 19 type I cyst and seven patients of 15 type IVa , developing significantly more in the type IVa choledochal cyst ( P<0.05 ) . - pubmed
Therefore , closed careful follow - up is important in patients who underwent cyst excision with hepaticojejunostomy for type IVa choledochal cyst . - pubmed
MATERIALS AND METHODS : Analysis included 104 patients with MDS ( 24 refractory anemia , 32 refractory anemia with ringed sideroblasts , 34 refractory anemia with excess of blasts , 7 refractory anemia with excess of blasts in transformation to acute leukemia , and 7 chronic myelo - monocytic leukemia ) , 3 patients with acute myeloid leukemia from MDS , and 36 patients with myeloproliferative disease ( 23 chronic myeloid leukemia , 9 polycythemia vera , 4 idiopathic myelofibrosis ) . - pubmed
Eighty percentage of such mice developed adenomyoepitheliomas within 53 - 88 weeks . - pubmed
Pseudomembranous colitis , often related to Clostridium difficile toxins ; is a severe form of postantibiotic diarrhea . - pubmed
Rectal prolapsus in children is cured without recurrence in 98 % of cases . - pubmed
Combined primary subintimal and endoluminal angioplasty for ischaemic inferior - limb ulcers in diabetic patients : 5 - year practice in a multidisciplinary ' diabetic - foot ' service . - pubmed
MATERIALS AND METHOD : Since September 2002 until December 2007 , a consecutive series of 176 limbs with manifold ischaemic wounds in 161 diabetic patients were treated by associated multilevel angioplasties in a multidisciplinary ' diabetic - foot team ' ( a third - line diabetic - care institution integrating two departmental hospitals ) . - pubmed
The 30 - day survival rate was 99 % ( one patient died from myocardial infarction ) . - pubmed
METHODS : In a prospective cohort study , 116 patients with suspected unresectable pancreatic cancer referred from peripheral hospitals ( 107 ) or our own gastroenterology department ( 9 ) were analysed . - pubmed
CT scans from referral centres were reviewed and in case of locally advanced disease or uncertain metastatic disease , patients underwent a laparoscopy to detect CT - occult metastases . - pubmed
Patients without metastases were offered 5 - FU based chemoradiotherapy . - pubmed
Locally advanced disease was confirmed in 59 ( 55 % ) patients and metastatic disease was found in 24 patients ( 22 % ) . - pubmed
CONCLUSION : Correct staging is difficult in patients with suspected locally advanced pancreatic cancer and should preferably be performed in centres with technically advanced equipment and experienced radiologists . - pubmed
Although Toxoplasma was discovered in 1908 , it was only in the 1950s that the extent of the infection in humans and domestic animals was realised and work was undertaken to elucidate its life cycle ( reviewed elsewhere in this edition ) . - pubmed
We report a case of an 56 - years old man who abruptly presented with right upper quadrant abdominal pain . - pubmed
These mice present with an elevated incidence of spontaneous histologic lesions , including cataracts , hyperplasia of Brunner 's gland and mucosal hyperplasia in the duodenum . - pubmed
In addition , osteogenic tumors in mice tails , such as osteoma and osteosarcoma were detected . - pubmed
Rightward hemispheric asymmetries in auditory language cortex in children with autistic disorder : an MRI investigation . - pubmed
PURPOSE : determine if language disorder in children with autistic disorder ( AD ) corresponds to abnormalities in hemispheric asymmetries in auditory language cortex . - pubmed
METHODS : MRI morphometric study in children with AD ( n = 50 ) to assess hemispheric asymmetries in auditory language cortex . - pubmed
These issues of life , death , and consciousness are discussed in the context of Mike , the headless chicken , who survived for 18 months , and in the context of consciousness with high degrees of intellectual and cognitive function in a congenitally anencephalic brain ; additionally , in the reanimation work of Soviet scientists in the 1920 - 30s , and in auditory sentence processing in patients in comatose , vegetative , and minimally conscious states . - pubmed
SUMMARY : Postoperative radiotherapy improves survival in patients with high - risk pathological features at radical prostatectomy at the cost of moderate urinary and bowel toxicity . - pubmed
Efficacy of tart cherry juice in reducing muscle pain during running : a randomized controlled trial . - pubmed
Tart cherries , rich in antioxidant and anti - inflammatory properties , may have a protective effect to reduce muscle damage and pain during strenuous exercise . - pubmed
This study aimed to assess the effects of tart cherry juice as compared to a placebo cherry drink on pain among runners in a long distance relay race . - pubmed
RESULTS : While both groups reported increased pain after the race , the cherry juice group reported a significantly smaller increase in pain ( 12 + /- 18 mm ) compared to the placebo group ( 37 + /- 20 mm ) ( p & lt ; .001 ) . - pubmed
The patients with VMA(+ ) progressive disease died later than those with VMA(- ) tumors ( P = .047 ) . - pubmed
These results show that increased urinary VMA predicts poor outcome for patients with favorable tumor sites . - pubmed
Urinary VMA can be useful risk determinant in combination with other biological determinants to predict prognosis of patients with localized neck , thoracic or pelvic tumors . - pubmed
In high - risk patients , negative spot test or normal level of urinary VMA at diagnosis might be used for identification of a group of patients with more favorable prognosis . - pubmed
Furthermore , lethally irradiated mice transplanted with E13 fetal liver cells from Mcl-1 / Myc bitransgenic mice uniformly died of stem / progenitor cell tumors . - pubmed
OBJECTIVE : To study the efficacy of adjunctive levetiracetam therapy compared with placebo in the treatment of subjects with depression with bipolar disorder . - pubmed
CONCLUSIONS : Levetiracetam adjunctive therapy was not superior to placebo in the short - term treatment of subjects with depression with bipolar disorder in the population studied . - pubmed
On the sixth day , after delivery , the patient was discharged seizure - free . - pubmed
Etanercept in the treatment of psoriasis and psoriatic arthritis with concomitant hepatitis C virus infection : clinical and virological study in three patients . - pubmed
We describe three psoriatic patients with HCV , one with concomitant alcoholic hepatitis , who were treated with etanercept monotherapy for six months . - pubmed
We obtained good clinical responses for both psoriasis and arthritis in all three patients . - pubmed
Our results add to accumulating data suggesting that etanercept represents a valuable therapeutic option for treatment of HCV - positive psoriatic patients , with an acceptable safety profile in the short - term . - pubmed
However , etanercept treatment of HCV cases with concomitant alcoholic hepatitis must be undertaken with caution . - pubmed
bovis severely decreased the virulence of the bacteria when assessed in a progressive model of pulmonary tuberculosis in Balb / c mice . - pubmed
A number of features of the pathology occurring in spontaneously hypertensive stroke prone rats ( SHRSPs ) , such as MRI brain signal abnormalities , the presence of high protein content in cerebrospinal fluid and vessel wall thickening , seem to indicate that this strain is a suitable model for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy ( CADASIL ) . - pubmed
Climate teleconnections and recent patterns of human and animal disease outbreaks . - pubmed
However , the immune status of livestock ( Rift Valley fever ) and human ( chikungunya ) populations is a factor that is largely unknown but very likely plays a role in the spatial - temporal patterns of these disease outbreaks . - pubmed
The goal of this study is to validate whether the seven mRNAs and three proteins previously reported as biomarkers are capable of discriminating patients with oral squamous cell carcinomas ( OSCC ) from healthy subjects in independent cohorts and by a National Cancer Institute ( NCI)-Early Detection Research Network ( EDRN)-Biomarker Reference Laboratory ( BRL ) . - pubmed
Lastly , one of our patients died from an aggressive endometrioid ovarian bilateral tumour associated with an endometrial adenocarcinoma . - pubmed
Cytology and human papillomavirus testing 6 to 12 months after ASCUS or LSIL cytology in organized screening to predict high - grade cervical neoplasia between screening rounds . - pubmed
Between January 2005 and April 2008 , 692 study women with screening - detected ASCUS / LSIL cytology 6 to 12 months earlier returned for HPV mRNA and DNA testing and repeat cytology . - pubmed
In conclusion , both positive HPV mRNA and DNA test results have a high enough long - term prediction of CIN2 + risk to consider referral to colposcopy as good practice when performed in delayed triage of women with ASCUS / LSIL cytology . - pubmed
Does preoperative atrial fibrillation portend a poorer prognosis in patients undergoing isolated aortic valve replacement ? - pubmed
Patients who underwent concomitant atrial arrhythmia surgery / ablation were excluded . - pubmed
Preop - AF patients were generally older ( mean age , 73 vs 68 years ; P & lt ; 0.001 ) and presented more often with comorbidities including congestive heart failure , diabetes , and cerebrovascular disease ( all P & lt ; 0.05 ) . - pubmed
There was a trend toward increased 30 - day mortality in patients with preop - AF on multivariate analysis ( P = 0.051 ) . - pubmed
Using these nanoparticles , we successfully imaged lymphatic networks and vasculature of xenografted tumours in living mice . - pubmed
inhibited carrageenan - induced rat paw oedema ( P & lt ; 0.001 ) . - pubmed
Cardiotoxicity to these drugs is not an uncommon adverse effect and has been reported in 1%-18 % of patients . - pubmed
We describe here the case of a 55 - year - old man who presented with cardiogenic shock and ECG signs of ST - elevation myocardial infarction . - pubmed
We measured quality of life ( QOL ) among individuals receiving treatment for human immunodeficiency virus ( HIV ; n = 45 ) , active tuberculosis ( TB ; n = 44 ) and both TB and HIV ( n = 9 ) in Rio de Janeiro , Brazil . - pubmed
Rapid resolution of acute subdural hematoma in child with severe head injury : a case report . - pubmed
CASE PRESENTATION : A 7 - year - old Asian girl with traumatic acute subdural hematoma was transferred to our hospital for an emergency operation based on the results of an initial computed tomography scan and neurological examination . - pubmed
The patient was discharged with mild confusion 40 days after the admission . - pubmed
CONCLUSION : A follow - up computed tomography scan is strongly recommended before surgery when a child with a severe head injury presents with any sign of neurological improvement , especially with a mixed density hematoma on the initial computed tomography scan . - pubmed
Neuropsychiatric symptoms in elderly inpatients : a multicenter cross - sectional study . - pubmed
BACKGROUND / AIMS : We determined the prevalence of neuropsychiatric symptoms in geriatric rehabilitation patients to compare neuropsychiatric symptoms between patients with and without dementia , and to evaluate associations linking severity of cognitive impairment and neuropsychiatric symptoms . - pubmed
RESULTS : Of the 194 patients , 149 ( 76.8 % ) had dementia , and 154 ( 79.4 % ) had exhibited at least one neuropsychiatric symptom during the past week . - pubmed
CONCLUSION : The prevalence of neuropsychiatric symptoms among geriatric rehabilitation patients was high but not higher than in elderly outpatients . - pubmed
BACKGROUND : Human embryonic stem cells ( hESCs ) serve as a potential unlimited ex vivo source of cardiomyocytes for disease modeling , cardiotoxicity screening , drug discovery , and cell - based therapies . - pubmed
BACKGROUND : Prevention of post - spinal hypotension in obstetric patients can be accomplished using intravenous fluid expansion and prophylactic use of sympathomimetic drugs . - pubmed
Reactive hypertension occurred in one patient ( 2.2 % ) and bradycardia in two patients ( 4.4 % ) in Group A. - pubmed
Six patients complained of nausea in Group B ( 13.3 % ) compared to one in Group A. - pubmed
Uncovering and dissecting the genotoxicity of self - inactivating lentiviral vectors in vivo . - pubmed
Vaccines to prevent Trypanosoma cruzi infection in humans or animals are not available , and in many settings , dogs are an important source of domestic infection for the insect vector . - pubmed
Outcomes with abiraterone acetate in metastatic castration - resistant prostate cancer patients who have poor performance status . - pubmed
BACKGROUND : Although abiraterone acetate ( abiraterone ) has proven efficacy in two randomised phase 3 trials in metastatic castration - resistant prostate cancer ( mCRPC ) , patients who had an Eastern Cooperative Oncology Group ( ECOG ) performance status ( PS ) & gt;=2 were either excluded or under - represented in these trials . - pubmed
OBJECTIVE : To compare outcomes in ECOG PS 0 - 1 and & gt;=2 in mCRPC patients treated with abiraterone . - pubmed
DESIGN , SETTING , AND PARTICIPANTS : Cancer registries from three Canadian centres were used to retrospectively identify mCRPC patients ( postdocetaxel and docetaxel - naive ) treated with abiraterone . - pubmed
PATIENT SUMMARY : We found that advanced prostate cancer patients who have worse performance status ( PS ) derive less benefit from abiraterone , indicating that earlier treatment before PS declines could improve outcomes . - pubmed
Transarterial treatments , frequently provided in an outpatient setting , are now safely and effectively being applied to patients with even advanced malignancy or partially decompensated cirrhosis . - pubmed
The article deals with a case of comparison of apneic oxygenation ( AO ) and high frequency jet ventilation ( HFJV ) during double level tracheal resection and reconstruction in patient with multifocal tracheal stenosis and underlying cerebral trauma . - pubmed
These observations evident about the necessity to study the role of hyperoxia , hypercapnia and cerebral hyperemia in patients with underlying cerebral trauma undergoing tracheal resection and reconstruction . - pubmed
Retraction notice to " PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines " [ Eur . - pubmed
DESIGN : This study enrolled 30 children with ASD and 19 healthy children . - pubmed
Twenty - one ( 35.6 % ) patients had intrinsic sphincter deficiency ( ISD ) . - pubmed
Procedures for prolapse were done in four ( 6 % ) patients . - pubmed
Leiomyomas and matched normal myometrium from each woman were analyzed in vitro . - pubmed
METHODS : We gathered clinical and imaging data of 336 young ICH patients between age 16 and 49 treated in the Helsinki University Central Hospital . - pubmed
METHODS : 100 female patients with AUB were enrolled in the study . - pubmed
MATERIALS AND METHODS : Patients aged & lt;18 years who underwent PNL for renal stones of sizes 10 - 20 mm between August 2011 and March 2014 in 3 referral centers were reviewed retrospectively . - pubmed
We also designed an experiment to investigate the location of iRGD - modified SSL when co - administered with free iRGD or free RGD to B16 - F10 tumor bearing nude mice . - pubmed
This study was to investigate the effect of Nidus Vespae decoction ( NVD ) on tumor cell viability and immunoregulating functions of human peripheral blood immune cells . - pubmed
The majority of patients were male ( range , 50 % to 74 % ) , and & lt;10 % had structural heart disease . - pubmed
In the randomized controlled trial component of the dual - design study , the 5 - year Kaplan - Meier estimates of the incidence of arrhythmic events were 7 % among patients who underwent ablation and 77 % among patients who did not undergo ablation ( relative risk reduction : 0.08 ; 95 % confidence interval : 0.02 to 0.33 ; p<0.001 ) . - pubmed
In the observational cohorts of asymptomatic patients who did not undergo catheter ablation ( n=883 , with follow - up ranging from 8 to 96 months ) , regular supraventricular tachycardia or benign atrial fibrillation ( shortest RR interval & gt;250 ms ) developed in 0 % to 16 % , malignant atrial fibrillation ( shortest RR interval & lt;=250 ms ) in 0 % to 9 % , and ventricular fibrillation in 0 % to 2 % , most of whom were children in the last case . - pubmed
CONCLUSIONS : The existing evidence suggests risk stratification with an electrophysiological study of patients with asymptomatic pre - excitation may be beneficial , along with consideration of accessory - pathway ablation in those deemed to be at high risk of future arrhythmias . - pubmed
Distal coronary embolization following acute myocardial infarction increases early infarct size and late left ventricular wall thinning in a porcine model . - pubmed
The aims of this study were to evaluate the effects of DCE sufficient to cause no - reflow on infarct size , cardiac function and ventricular remodeling in a porcine acute myocardial infarction model . - pubmed
Awakening Blood Pressure Rise in a Patient with Spinal Cord Injury . - pubmed
CASE REPORT : We report the case of a 66 - year - old man with a history of spinal cord injury , and who had remarkable awakening BP rise in ambulatory BP monitoring . - pubmed
Hookworms are recognised as a cause of iron - deficiency anaemia in endemic areas . - pubmed
[ Relationship between myocardial microRNA-30a expression and myocardial fibrosis in rats post myocardial infarction ] . - pubmed
METHODS : Rats were randomly divided into 1 week MI group ( n=11 ) , 2 weeks MI group ( n=13 ) and 4 weeks MI group ( n=15 ) by applying random number table after left anterior descending coronary artery ligation . - pubmed
In the present study we have used zebrafish embryos to model Cronobacter infections in vivo using wild type and genetically engineered strains . - pubmed
Second , a 25 - year - old man with polyostotic disease of the left leg who received both surgical and medical treatment . - pubmed
Objective measures that detect changes in neurological function in FA patients are needed to facilitate therapeutic clinical trials . - pubmed
The effect of epicatechin on oxidative stress and mitochondrial damage induced by homocycteine using isolated rat hippocampus mitochondria . - pubmed
In this study , we have evaluated the effects of epicatechin ( EC ) on mitochondrial damage induced by homocycteine ( Hcy ) using isolated rat hippocampus mitochondria in vivo . - pubmed
Effects of Acupuncture on 1 - chloro-2,4 - dinitrochlorobenzene - induced Allergic Contact Dermatitis in Mice . - pubmed
BALB / c mice received 1 - chloro-2,4 - dinitrobenzene ( DNCB ) application to build AD - like model . - pubmed
Background : The progression of human African trypanosomiasis from the early hemolymphatic stage to the late meningoencephalitic stage is of critical diagnostic importance as it determines the choice of potentially toxic drug regimens . - pubmed
The Treatment of Cataract in Children . - pubmed
MATERIALS AND METHODS : In this study , 10 adults with disc displacement and painful , hypermobile TMJ were selected . - pubmed
Patients with rheumatoid arthritis and parafunctional habits such as teeth clenching and grinding and biting of the cheeks or any other objects and those who had undergone surgery were excluded from this study . - pubmed
METHODS : The British Columbia Hepatitis Testers Cohort ( BC - HTC ) includes ~1.7 million individuals tested for HCV / HIV or reported HBV / HCV / HIV / tuberculosis cases in BC from 1990 to 2015 , linked to administrative datasets including physician visit , hospitalization and prescription drug records . - pubmed
A 63 - year - old man developed a syndrome of cauda equine , with the numbness which is a left lower extremity from the left buttocks , weakness of left leg , and a dysfunction of bladder and bowel . - pubmed
Infective endocarditis due to Burkholderia cepacia in a neonate : a case report . - pubmed
METHODS : A double blinded randomised control trial was performed that included mandibular primary molars in children of age 4 - 7 years with pulp necrosis . - pubmed
RESULTS : Fifteen patients with PCL were diagnosed during the study period ; fourteen had second trimester scans . - pubmed
Anomalies of the CC were evident in 8/14 patients during the 2nd trimester scan and included : short length ( n = 4 ) , increased thickness ( n = 1 ) , complete agenesis ( n = 2 ) and partial agenesis ( n = 1 ) . - pubmed
One child was diagnosed with attention deficit disorder . - pubmed
Here , we compare the repeatability and reliability of exploratory behaviors between zebrafish strains selectively bred to display contrasting behavioral responses to stressors that represent the proactive - reactive axis . - pubmed
Reactive zebrafish generally showed the highest reliability and repeatability of exploratory behavior compared to proactive zebrafish and a separate wild caught strain . - pubmed
We did a meta - analysis including 8 clinical trials to verify the efficacy and safety of blinatumomab in patients with relapsed / refractory ALL and NHL . - pubmed
ALL patients manifested better therapeutic response than NHL patients and a reduced tumor load favored the clinical response . - pubmed
METHODS : From March 2009 to December 2014 , 285 patients presented with type B aortic dissection . - pubmed
Computed tomography angiography before discharge showed complete thrombosis of the false lumen of the descending aortic in 34 patients . - pubmed
Three patients died during follow - up : 1 died in a traffic accident and 2 died of sudden death . - pubmed
CONCLUSIONS : For patients with complicated type B aortic dissection , implantation of a stent graft under direct vision ( hybrid surgery ) is easily performed and provides satisfactory middle- and long - term outcomes . - pubmed
To our knowledge , this is the first report of powdery mildew caused by Oidium anamorph of E. - pubmed
( v ) In all patients with FPHL , assessment of a possible androgen excess is mandatory . - pubmed
Molecular remissions are observed in chronic adult T cell leukemia / lymphoma in patients treated with mogamulizumab . - pubmed
Combination Effect of Titrated Extract of Centella asiatica and Astaxanthin in a Mouse Model of Phthalic Anhydride - Induced Atopic Dermatitis . - pubmed
We investigated the therapeutic efficacy of the ointment form of TECA , AST and a TECA + AST combination in a mouse model of AD to see whether a combination of the reduced doses of 2 compounds could have a synergistic effect . - pubmed
METHODS : An AD - like lesion was induced by the topical application of 5 % PA to the dorsal ear and back skin of an Hos : HR-1 mouse . - pubmed
Patients were classified into three subgroups : EOPE , LOPE , and control groups . - pubmed
The optimal treatment strategies and outcomes of patients with metastatic ACC remain areas of active interest . - pubmed
We retrospectively reviewed patients with ACC who were treated with systemic therapy between January 1997 and October 2016 at The Ohio State University Comprehensive Cancer Center . - pubmed
We identified 65 patients diagnosed with ACC during the given time period , and 36 patients received systemic therapy for distant metastatic disease . - pubmed
Six patients with liver metastases treated with systemic therapy who received liver - directed therapy with either transarterial chemoembolization ( TACE ) or selective internal radiation therapy ( SIRT ) had longer survival than those who did not ( p = 0.011 ) . - pubmed
Our data expands the knowledge of clinical characteristics and outcomes of patients with ACC and suggests a possible role for incorporating liver - directed therapies for patients with hepatic metastases . - pubmed
This is due to increasing survival rates among patients with metastatic disease , early detection as a result of increasing availability of spinal MRI , the recognition of the oligometastatic state as a distinct sub - group of favorable metastatic patients and the advent of stereotactic body radiotherapy ( SBRT ) . - pubmed
As a result , the multidisciplinary evaluation of cases prior to SBRT is emphasized with the intent to identify patients who could benefit from surgical stabilization or down - staging of epidural disease . - pubmed
Cisplatin ( CDDP)-based chemotherapy is a standard strategy for the clinical treatment of patients with bladder cancer ( BC ) . - pubmed
PURPOSE : The aim of this study was to test the antiviral effectivity of potassium peroxymonosulfate ( RUBYSTA , KYORIN ) against five epidemic keratoconjunctivitis - related types of Human adenovirus D in vitro . - pubmed
Overall , potassium peroxymonosulfate demonstrated sufficient inactivation of the major epidemic keratoconjunctivitis - causing Human adenovirus D to be considered for disinfection and prevention purposes in ophthalmological clinics and hospitals . - pubmed
Role of turmeric extract in minimising mucositis in patients receiving radiotherapy for head and neck squamous cell cancer : a randomised , placebo - controlled trial . - pubmed
OBJECTIVE : To determine the role of turmeric extract in reducing mucositis in patients undergoing radiotherapy for head and neck cancer . - pubmed
All patients were assessed for oral mucositis on a weekly basis during treatment and two months post - treatment using the National Cancer Institute Common Terminology Criteria for Adverse Events and World Health Organization criteria . - pubmed
The severity of mucositis was progressive in the control group , with four patients developing grade 3 mucositis by week four . - pubmed
In group A , however , the majority of patients ( 73.3 per cent ) had grade 1 mucositis after four weeks of treatment . - pubmed
CONCLUSION : Turmeric extract reduces the incidence and severity of radiation - induced mucositis , which can benefit patients undergoing radiation for head and neck cancer . - pubmed
Liver Stiffness Measurement by Vibration Controlled Transient Elastography Does Not Correlate to Hepatic Iron Overload in Children With Sickle Cell Disease . - pubmed
CONCLUSION : VCTE is a noninvasive technology that is feasible in children with SCD . - pubmed
METHODS : Data for patients with malignant neoplasms of the oral cavity registered in the Cancer Registry Database of Taipei Veterans General Hospital between 2002 and 2011 were retrieved . - pubmed
RESULTS : A total of 191 OSCC patients were included for retrospective analysis ; 177 were males and 14 were females . - pubmed
Patients with diabetes , moderate or poor cell differentiation , perineural invasion , and extracapsular spread presented lower 5 - year OS rates ( HR=1.87 , 1.65 , 2.42 , and 2.14 , respectively ) , and patients with perineural invasion , positive cut margin , and extracapsular spread presented lower 5 - year DFS rates ( HR=1.57 , 1.62 , and 1.71 , respectively ) . - pubmed
We present a single - patient study in which a patient with Parkinson ' s disease traversed a doorway under different cueing conditions . - pubmed
Omalizumab in children and adolescents with chronic spontaneous urticaria : case series and review of the literature . - pubmed
We reported our experience of six patients with chronic spontaneous urticaria ( CSU ) treated with omalizumab . - pubmed
Thus far , two patients have experienced a complete CSU regression over 12 months after the final omalizumab administration . - pubmed
Quantitative characterization of the PVSV morphology in MRI images in healthy subjects may serve as a reference for detecting disease related PVS and/or blood vessel alterations in patients with brain diseases . - pubmed
CASE PRESENTATION : Our patient was a 39 - year - old Ethiopian man who presented with left - side body weakness of 6 years ' duration with worsening of symptoms of 6 months ' duration . - pubmed
The patient was reoperated for tension pneumocephalus 48 hours after the initial surgery . - pubmed
Severe acute respiratory syndrome - coronavirus 2 ( SARS - CoV-2 ) has rapidly caused a global pandemic associated with a novel respiratory infection : coronavirus disease-19 ( COVID-19 ) . - pubmed
In teleost fishes , reptiles and birds , the biology of light sensitivity is more complicated as cells and tissues can be directly light responsive . - pubmed
In the case of teleosts , in particular the zebrafish model system , not only do peripheral tissues have a circadian pacemaker , but possess clear , direct light sensitivity . - pubmed
BACKGROUND : Aortic aneurysms occur concomitantly with malignancy in approximately 1.0 - 17.0 % of patients . - pubmed
METHODS : Patients with aortic aneurysms , with and without malignancy between 2005 - 2017 were identified within institutional databases using Current Procedural Terminology and International Classification of Disease codes . - pubmed
Inclusion criteria included complete chemotherapy documentation , a minimum of three multiplanar axial / coronal imaging or ultrasonography prior to , during , and after receiving therapy or two studies for patients without malignancy . - pubmed
RESULTS : 159 ( 172 aneurysms ) patients with malignancy and 127 ( 149 aneurysms ) patients without malignancy were included . - pubmed
Average patient demographics were : 74.4 + -9.8 - years - old , Caucasian ( 66.8 % ) , male ( 70.3 % ) , with hypertension ( 71.1 % ) , current smoking ( 24.5 % ) , coronary atherosclerotic disease ( 26.2 % ) , and AAA ( 71.0 % ) . - pubmed
CONCLUSION : Small aortic aneurysms with concomitant malignancies are discovered at smaller initial sizes , grow at similar rates , require fewer interventions , and have fewer ruptures and acute dissections than patients without malignancy . - pubmed
Patients with concomitant disease can be confidently prescribed to standard institutional aneurysm surveillance protocols . - pubmed
Overall , we recommend treatment of the malignancy prior to small aortic aneurysm repair as these aneurysms behave similarly to those in patients without malignancy . - pubmed
Incidence and Clinical Impact of Inflammatory Fluorodeoxyglucose Positron Emission Tomography Uptake After Neoadjuvant Pembrolizumab in Patients with Organ - confined Bladder Cancer Undergoing Radical Cystectomy . - pubmed
METHODS : After a 4 - week lead - in phase ( baseline ) , 9 men and 12 postmenopausal women ( 50 - 75 years ) with chronic inflammation received two phases of 10 - week supplementation with 3 g / day EPA and DHA in a random order , separated by a 10 - week washout . - pubmed
To elucidate the mechanisms of memory impairment after chronic neonatal intermittent hypoxia ( IH ) , we employed a mice model of severe IH administered at postnatal days 3 to 7 . - pubmed
Surface kymography in three planes were performed in 180 patients following myocardial infarcts , and these were compared with the results of coronary angiography and selective laevocardiography . - pubmed
Of the 12 patients treated , 11 had measurable tumor criteria and 5 of these responded to treatment . - pubmed
An antiserum has been found in a nonimmunized rabbit which reacts strongly with a system of filaments in various fibroblasts , epithelial cells , macrophages and neuroblastoma . - pubmed
A new mechanism of myelopathic changes in patients with mucopolysaccharidosis is described . - pubmed
Myelography is indicated in the evaluation of these patients because surgical decompression may reverse the progressive neurological deficits . - pubmed
The theoretical concept is supported by experimental findings in frog tadpoles with " congenital " dislocation of the knee joint produced by osteolathyrogenic diet . - pubmed
The suggested pathogenetic mechanism appears to apply even to the congenital dislocation of the hip in man . - pubmed
Gestational hyperlipidemia in the rat is characterized by accumulation of n - 6 and n - 3 fatty acids , especially docosahexaenoic acid . - pubmed
Compared to non - pregnant rats , gestational hyperlipidemia was also associated with a lower proportion but similar quantity of linoleic acid in maternal carcass and adipose stores . - pubmed
We conclude that gestational hyperlipidemia in the rat is characterized by a relative but not quantitative decrease in whole - body stores of n - 6 fatty acids and a marked proportional and quantitative increase in docosahexaenoic acid in maternal organs and in the conceptus . - pubmed
[ Enhancement effect of fat emulsion for intravenous use ( intralipos ) on the growth of a human breast cancer cell line in culture : preliminary report ] . - pubmed
Gallid herpesvirus 1 ( infectious laryngotracheitis virus ): cloning and physical maps of the SA-2 strain . - pubmed
In our environment , some children with allergic respiratory pathology do not have as favorable an evolution as expected after three years of immunotherapy with D. - pubmed
There were 38 boys ( 76 % ) and 12 girls ( 24 % ) with rhinitis and bronchial asthma . - pubmed
Two symptomatic and two asymptomatic complications arose , including permanent hemiparesis in one patient . - pubmed
Bifurcation and linear antibacterial prostheses were used in 9 patients with a high risk of suppuration verified by cultures of discharge from ulcers and lymph nodes , and the presence of lymphangitis and lymphadenitis . - pubmed
The effect was positive in 8 patients , 2 of them had superficial suppuration of the operative wounds . - pubmed
The effects of dietary counselling on food and nutrient intake and weight loss were studied over a two - year period in 32 obese children ( relative weight greater than 120 % ) with intensive treatment ( Group I ) and in 16 obese children treated in a school health - care setting ( Group II ) . - pubmed
The obese children were treated for one year and observed for another year . - pubmed
The decrease in energy intake was significantly correlated with the reduction in body fat mass over the first year ( rs = 0.50 ; P = 0.05 , n = 16 ) in obese children passing through their pubertal growth spurt and to the reduction in relative weight over the first year ( rs = 0.90 ; P less than 0.05 , n = 5 ) , as well as to the decrease in fat mass over the second year ( rs = 0.70 ; P less than 0.05 , n = 11 ) in adolescents beyond their growth spurt . - pubmed
[ Characteristics of the cardiovascular system in children with primary arterial hypotension ] . - pubmed
Overall 120 children aged 12 to 15 years with primary arterial hypotension and different variants of the disease course ( grave , of medium gravity or mild ) were examined . - pubmed
Both patients had an eosinophilia ( 10.5 and 19 % ) and specific antibodies against Onchocerca volvulus . - pubmed
Microfilaria were demonstrated in the skin of the younger man . - pubmed
447 children between 0 and 24 months with diaper dermatitis were treated by topical application of Parfenac - Fettsalbe ( Bufexamac ) . - pubmed
Very good ( no efflorescences remaining ) and good results ( some remaining efflorescences ) were thus found in more than 80 % of patients treated : with respect to corticosteroid advoidance this can be regarded as an effective antiphlogistic medication for diaper dermatitis . - pubmed
Psychopathology and plasma cortisol responses to dexamethasone in prepubertal psychiatric inpatients . - pubmed
This study of 51 prepubertal psychiatric inpatients evaluates plasma cortisol measurements at 8 AM , 4 PM , and 11 PM before and after dexamethasone was administered in counterbalanced order at doses of 0.5 mg and 1.0 mg . - pubmed
Approximately 76.5 % of the children had an affective disorder . - pubmed
Bovine leukaemia virus and enzootic bovine leukosis . - pubmed
Infection of bovines with bovine leukaemia virus ( BLV ) manifests itself in either of two ways : 30 - 70 % of carriers develop persistent lymphocytosis ( PL ) , with the viral genome integrated at a large number of different sites in the DNA of the affected B - lymphocytes , without causing any chromosomal abnormalities . - pubmed
Although bovine leukosis is not of major economic importance , its eradication is desirable and feasible in countries with a relatively low incidence , by means of testing and elimination . - pubmed
It is proposed that multicenter collaborative studies be designed to evaluate proposed therapies for children with IgAN associated with proliferative glomerular lesions , particularly those in whom hypertension , proteinuria , and depressed glomerular filtration rate are found . - pubmed
We report a patient with sudden memory dysfunction following hemorrhage into the anterior nucleus of the left thalamus that was shown neuropathologically to disrupt the mamillothalamic fasciculus , one of the principal components of the limbic system . - pubmed
The toxicity of 1 -[ 2 -( diethylamino ) ethyl ] reserpine ( DL-152 ) has been measured for 4 transplantable mouse tumors . - pubmed
DL-152 was found to be toxic to cells of all the tumor models tested ( KHT fibrosarcoma , RIF-1 fibrosarcoma , EMT-6 adenocarcinoma and Lewis lung carcinoma ) when the drug was given by intraperitoneal injection to the tumor - bearing mouse and cell survival was measured by excision assay . - pubmed
Hyperthermia ( temperature of at least 40.5 degrees C for at least one hour ) associated with drug intoxication was identified in 12 patients over a 5 - yr period . - pubmed
Hyperthermia was present in four patients on admission , but its onset was delayed up to 12 h in the remainder . - pubmed
Outcome of hyperthermic patients was poor : five died and four had severe permanent neurologic sequelae . - pubmed
Clinical signs common to patients who developed hyperthermia were increased muscular activity and absence of sweating . - pubmed
Five patients suffered seizures , and four did not respond to anticonvulsant medication until body temperature was lowered . - pubmed
Both serum cholesterol and triglyceride levels are initially decreased in patients aged 50 to 69 with cerebral infarction , whereas only cholesterol is decreased in patients 60 to 69 with transient ischemic attacks . - pubmed
Influence of estrogen administration on tumor characteristics and survival in women with cutaneous melanoma . - pubmed
A prospective study on 289 women with clinical stage I cutaneous melanoma was done to determine the relationship between estrogen administration , tumor characteristics , and survival . - pubmed
Eighty - two women took oral contraceptives ( OC ) and 44 took menopausal estrogens ( MPE ) prior to the diagnosis of melanoma . - pubmed
A PSE-4 - producing Escherichia coli strain was resistant to Sch 34343 . - pubmed
Pharmacokinetics of tocainide in patients with severe renal failure . - pubmed
to 20 patients with renal failure due to various causes , and to 8 healthy controls . - pubmed
The peak plasma concentrations in the patients with pyelonephritis ( 3.80 micrograms / ml ) and interstitial nephritis ( 3.74 micrograms / ml ) but not in those with glomerulonephritis ( 3.17 micrograms / ml ) differed from that in healthy volunteers ( 3.24 micrograms / ml ) . - pubmed
The predictive value positive of serum iron studies and erythrocyte indices in differentiating between iron deficiency anemia and the anemia of chronic disease ( ACD ) were determined in 82 hospitalized patients with an iron - binding saturation of 15 percent or less . - pubmed
Iron deficiency was present in 83 percent of patients with a mean corpuscular volume ( MCV ) of 75 microns3 or less , but only 2 percent of patients with an MCV of 86 microns3 or greater . - pubmed
The therapeutic activity of cisplatin was explored in three consecutive patients with locoregional squamous cell carcinoma of the anus who received no prior therapy . - pubmed
Study of mucopolysaccharides in experimental conjunctival diphtheria of the guinea pig ] . - pubmed
[ Current importance in the treatment of bronchitis with sulfonamides in children ] . - pubmed
[ Specificity of vertebral compression fractures in children ] . - pubmed
[ Serum and erythrocyte electrolytes in children with cardiac arrhythmias ] . - pubmed
Microcirculatory changes and general responses to 5 - hydroxytryptamine in normothermic and hypothermic mice . - pubmed
Spontaneous rupture of the stomach in a healthy adult man after sodium bicarbonate ingestion . - pubmed
The group was compared with three others ( 1 ) 113 healthy subjects , untested for acetylator phenotype , ( 2 ) 16 slow - acetylator hypertensive patients treated with hydralazine for more than a year without developing SLE , and ( 3 ) 20 patients with idiopathic SLE . - pubmed
Periarteritis nodosa in spontaneously hypertensive rats -- immunohistological study and permeability test . - pubmed
Spontaneously hypertensive rats develop periarteritis nodosa spontaneously with high incidence . - pubmed
This fact suggests that periarteritis nodosa in spontaneously hypertensive rats may not be arteritis of immune complex type . - pubmed
In male spontaneously hypertensive rats periarteritis nodosa is observed in 6 of 11 and the arterial permeability increases more pronouncedly in the positive group , whereas 5 female spontaneously hypertensive rats of various ages are free from periarteritis nodosa irrespective of high arterial permeability . - pubmed
Therefore , high arterial permeability does not always lead to regular development of periarteritis nodosa especially in female spontaneously hypertensive rats . - pubmed
Regrowth of aminoglycoside - resistant variants was seen when large inocula of two strains of Escherichia coli were incubated with gentamicin in concentrations well above their MICs ( 0.5 micrograms / ml ) . - pubmed
[ Agar cultures of blood forming cells from patients with various forms of hemopoietic dysplasia ] . - pubmed
The leukemic growth type was proved in 59 % of the patients with haematopoietic dysplasia . - pubmed
1 Fifty - seven patients with mild or moderate essential hypertension , mean age 50 ( range 31 - 69 ) were randomised to treatment with either captopril or atenolol . - pubmed
5 Two patients were excluded from the captopril group , one because of a reversible loss of taste and the other because of dizziness . - pubmed
Three patients were excluded from the atenolol group , two because of bradyarrhythmias and one because of inadequate blood pressure response . - pubmed
The selective toxicity of gonococcal lipopolysaccharide for the mucosa of human fallopian tubes , which is demonstrated in these studies , may be responsible in part for the specificity of naturally occurring gonococcal infections for humans . - pubmed
Two patients developed antepartum pulmonary edema after receiving hydrocortisone to promote fetal lung maturity . - pubmed
The third patient developed pulmonary edema shortly after delivery and after having received glucocorticoids antepartum . - pubmed
The stimulatory effect of a recently introduced saliva substitute ( Saliment ) on the parotid salivary secretion was experimentally investigated in 10 healthy individuals without signs or symptoms of xerostomia and in 11 patients with xerostomia due to Sjogren ' s syndrome . - pubmed
Further , in 15 patients with Sjogren ' s syndrome , the effect of Saliment on the sensation of xerostomia was examined in a double - blind clinical study with cross - over . - pubmed
Anergy and altered lymphocyte function in the injured patient . - pubmed
The immunologic competence of 16 patients , including 15 who had minor injuries and required less than 4 transfusions , was prospectively studied with skin testing , leukocyte counts , and protein electrophoresis . - pubmed
Ten patients with minor trauma responded to at least one of the antigen skin tests and were considered nonanergic ( NA ) . - pubmed
Lipoprotein levels and tissue lipids in fatty - fibrous atherosclerosis induced in rabbits by two years ' cholesterol feeding at a low level . - pubmed
A group of 12 young NZW rabbits of the same breeding strain were fed a diet enriched with 0.1 % cholesterol by weight . - pubmed
Two animals that died during this period showed no gross or microscopic atherosclerosis . - pubmed
In some animals this resulted in moderate hypercholesterolaemia . - pubmed
One animal that died at this time showed no atherosclerosis with a mean serum cholesterol level of 224 mg / dl . - pubmed
This resulted in definite hypercholesterolaemia in some animals , but a few resisted the treatment with mean serum cholesterol levels around 40 - 60 mg / dl . - pubmed
In general , animals with established hypercholesterolaemia showed severe atherosclerosis , but often of a more fibrous and less cellular nature than is usual in the rabbit . - pubmed
A reappraisal of the dog - heart infarct plasmalogen , its conception as a bis - phosphatidic acid and current recognition as an N - acyl phosphatidyl ethanolamine . - pubmed
We have re - examined the lipids from myocardial infarcts of cat , dog , rabbit and man , mainly through TLC methods , and confirm the identity of cat and dog " infarct plasmalogen " as an N - acyl phosphatidyl ethanolamine ( NAPE ) . - pubmed
This substance was not detected in infarcts of rabbit and man . - pubmed
The hypothalamo - neurohypophyseal function was evaluated in a patient with the chronic hypernatremia syndrome . - pubmed
In newborn piglets , moderate increases in sodium excretion by acetazolamide were accompanied by a marked kaliuresis . - pubmed
Serum was obtained from 7 patients with solid tumor , 12 patients with malignant CNS tumor , and 16 patients with acute leukemia . - pubmed
Immunocompromised patients are at risk of developing infections caused by Rhodococcus equi , a gram - positive bacillus that can cause pneumonia in patients with acquired immunodeficiency syndrome . - pubmed
Infection with R equi may go unrecognized by pathologists unaware of its presentation and appearance in cytologic material . - pubmed
Combined kidney - pancreas transplantation has become the treatment of choice for many patients with end - stage diabetic nephropathy . - pubmed
Pancreas transplantation ( PTx ) alone is an option for type I diabetic patients without end - stage diabetic nephropathy . - pubmed
Knowledge of factors contributing to or predicting the rate of renal deterioration ( including the effect of CsA on the patient 's renal function before transplantation ) is necessary to determine candidacy for either kidney - pancreas transplantation or PTx alone . - pubmed
To address this issue , we selected 12 pre - uremic patients with creatinine clearances ( CrCl ) above 40 ml / min and less than 100 ml / min to participate in a 6 - week oral CsA challenge test . - pubmed
The effects of oral micronized progesterone - administered at a low dose - on the endometrium and on bleeding pattern have been evaluated during a multicenter study in which 101 patients were involved . - pubmed
For a minimum of 6 months , patients who did not wish to have withdrawal bleeding ( 98 ) received the association of 17 beta - percutaneous estradiol ( 1.5 mg / d ) and oral micronized progesterone ( 100 mg / d , at bedtime ) during 25 days per month ( or 21 d/28 ) . - pubmed
The few women ( 3 ) who wished regular bleeding were given progesterone ( 300 mg / d ) with estradiol ( 3 mg / d ) , from the 16th to the 25th of the month . - pubmed
This situation makes it possible to minimize spottings and to maintain an amenorrhea in the majority of patients , thus letting us hoping for an improvement in the observance of this simplified therapy . - pubmed
A phase III trial was conducted in 40 patients with known or suspected skull base tumors to evaluate the safety and efficacy of high - dose gadodiamide injection for use as a paramagnetic contrast medium in conventional and dynamic magnetic resonance ( MR ) imaging . - pubmed
In patients who present with unheralded myocardial infarction both the severity and the extent of coronary atherosclerosis appear to be less than that in patients with chronic stable angina , thus suggesting that , in the latter , protective factors may prevent or delay the evolution towards acute coronary syndromes . - pubmed
Therefore , risk factors were compared in 88 consecutive patients ( 73 men ; mean age 56 + /- 9 years ) with unheralded myocardial infarction and a single , discrete , & gt ; 70 % stenosis in the proximal right , left circumflex or left anterior descending coronary artery ( Group 1 ) and in 55 consecutive patients ( 46 men ; mean age 58 + /- 9 years with chronic stable angina and multiple , diffuse , & gt ; 70 % stenoses localized both in the right and left coronary arteries ( Group 2 ) . - pubmed
Ocular ischemic syndrome in a child with moyamoya disease and neurofibromatosis . - pubmed
Patients with moyamoya disease may be particularly susceptible to the development of ocular ischemia due to the associated carotid occlusion . - pubmed
A 19 - month - old boy presented with neurofibromatosis and signs of ocular ischemia . - pubmed
Comparison of three intensive programs for chronic low back pain patients : a prospective , randomized , observer - blinded study with one - year follow - up . - pubmed
In a randomized , blinded study , we compared the outcome from a full - time functional restoration program with the outcome from shorter active rehabilitation programs for patients with chronic , disabling low back pain . - pubmed
The study initially included 132 patients , randomized into one of three treatment programs : ( 1 ) an intensive 3 - week multidisciplinary program ; ( 2 ) active physical training and back school ; or ( 3 ) psychological pain management and active physical training . - pubmed
The effects of cage density on pullet live performance and blood indices of stress were evaluated in two commercial White Leghorn strains housed at 38 , 32 , 26 , and 20 birds per cage from Day 1 to 6 wk of age , and 19 , 16 , 13 , and 10 birds per cage from 6 to 18 wk . - pubmed
Doppler estimation of left ventricular filling pressures in patients with hypertrophic cardiomyopathy . - pubmed
METHODS AND RESULTS : Thirty - five HCM patients ( 52+/-15 years ) underwent LV catheterization simultaneously with 2 - dimensional and Doppler echocardiography . - pubmed
PreA pressure estimation with these 2 methods was tested prospectively in 17 additional HCM patients with good results ( E velocity / flow propagation velocity , r=0.76 ; E / Ea , r=0.82 ) . - pubmed
CONCLUSIONS : LV filling pressures can be estimated with reasonable accuracy in HCM patients by measuring E velocity / flow propagation velocity or E / Ea . - pubmed
Smoking and therapeutic response to clozapine in patients with schizophrenia . - pubmed
BACKGROUND : Of patients with schizophrenia , 70 to 80 % smoke . - pubmed
Nicotine corrects certain information processing and cognitive psychomotor deficits seen in many patients with schizophrenia . - pubmed
METHODS : We assessed psychopathology and smoking in 70 patients with treatment refractory schizophrenia ( 55 smokers and 15 nonsmokers ) at baseline when they were receiving conventional antipsychotics and again after they were switched to clozapine . - pubmed
CONCLUSIONS : Certain patients with schizophrenia have contributing pathophysiologic mechanisms that respond favorably to either nicotine or clozapine . - pubmed
BACKGROUND & amp ; AIMS : Reinfection after treatment for Helicobacter pylori is uncommon in adults . - pubmed
SURGICAL REPAIR : The beneficial effect of myocardial revascularization on severe ischemic cardiomyopathy , the relevance of mitral valve repair in dilated cardiomyopathy , and the advantage of ventricular remodeling in patients with major ventricular dyskinesia has been clearly demonstrated . - pubmed
ADAPTED TREATMENT : Optimal management of each patient with advanced heart failure requires an adequate treatment selected among a wide range of medical and/or surgical strategies . - pubmed
Two female patients ( age 56 and 62 years ) and one male ( age 44 years ) presented with recurrent tracheobronchitis , a " difficult intubation " at the time of an emergency situation requiring tracheostomy . - pubmed
Preventing the spread of hepatitis B and C viruses : where are germicides relevant ? - pubmed
Hepatitis B virus ( HBV ) and hepatitis C virus ( HCV ) are the most prevalent bloodborne pathogens . - pubmed
Both viruses remain difficult to work with in the laboratory , but closely related animal viruses ( such as the duck HBV ) and the bovine viral diarrhea virus show considerable promise as surrogates for HBV and HCV , respectively . - pubmed
Prognostic value of left ventricular mass and its evolution during treatment in the Bordeaux cohort of hypertensive patients . - pubmed
Relationship between Trypanosoma cruzi and human chagasic megaesophagus : blood and tissue parasitism . - pubmed
The persistence of Trypanosoma cruzi in tissue and blood of 52 patients in the digestive form of chronic Chagas disease was studied . - pubmed
These data demonstrate that in the digestive form of Chagas ' disease , particularly in cases of megaesophagus , T. - pubmed
METHODS : In a prospective study of 107 patients affected by brain tumors , we assessed PE clinically and the rate of dilated vessels histologically . - pubmed
RESULTS : 6.5 % of the patients had an important erythema and 18.5 % had slight and/or localized PE . - pubmed
CONCLUSION : in the case of Streptococcus pneumoniae sepsis , a systematic search for Howell - Jolly bodies on blood smears and ultrasound examination of the abdomen for the presence of asplenia should be mandatory to detect isolated congenital asplenia . - pubmed
All three patients needed urgent surgical intervention with further laparotomies due to recurrent ulceration , perforation and fistula formation in addition to intensive supportive measures such as inotropes and total parenteral nutrition . - pubmed
PURPOSE : To measure the blood flow velocities in feeder vessels of patients with choroidal neovascularization ( CNV ) secondary to age - related macular degeneration . - pubmed
METHODS : We examined the early images of indocyanine green videoangiography ( v - ICGA ) in 29 patients ( 29 eyes ) with CNV , in whom feeder vessels could be identified by v - ICGA . - pubmed
Results were as follows : 1)The peripheral blood examinations revealed that 52.0 % of the examined have parasitemia , of which 95.3 % was P. - pubmed
Neither P. malaria nor P. - pubmed
Lack of effect of amino acids on the growth retardation due to unheated soybeans . - pubmed
[ The treatment of Proteus infections of the urinary tract with Lactobacillus acidolphus ] . - pubmed
Effect of diethylstilbestrol - induced tumorigenesis on the secretory activity of the rat anterior pituitary gland . - pubmed
Resistance to infection in burned patients . - pubmed
[ Features of the clinical picture and secretory function of the stomach in patients with peptic ulcer and their relation to various localizations of ulcers ] . - pubmed
Effects of pyruvate administration on infarct volume and neurological deficits following permanent focal cerebral ischemia in rats . - pubmed
The purpose of this study was to assess the neuroprotective effect and the neurological outcome after pyruvate administration in a model of ischemic stroke induced by permanent middle cerebral artery occlusion ( pMCAO ) in rats . - pubmed
Patients with beta - catenin - negative serous carcinomas had a poorer overall survival than patients with beta - catenin - positive serous carcinomas ( p = 0.013 ) . - pubmed
MATERIAL AND METHODS : 29 patients with Hodgkin ' s disease ( HD ) referred for baseline FDG PET imaging before treatment and without evidence of bone marrow ( BM ) involvement were included in the study . - pubmed
PATIENTS AND METHODS : We retrospectively reviewed all 11 patients ( 12 renal units ) treated with the combined approach of HoLEP and an upper - tract endourologic procedure for stone disease . - pubmed
Fourteen and 18 mm lesion gaps were created in a rat sciatic nerve lesion model . - pubmed
Bioassay ( P388 lymphocytic leukemia cell line and human cancer cell lines ) guided separation of an extract prepared from the previously chemically uninvestigated Texas grasshopper Brachystola magna led to isolation of the cancer cell growth inhibitory pancratistatin ( 1 ) , narciclasine ( 2 ) , and ungeremine ( 3 ) . - pubmed
A combination of atrioventricular block and sinoatrial block in a horse . - pubmed
Resistance based on slow - rusting genes has proven to be a useful strategy to develop wheat cultivars with durable resistance to rust diseases in wheat . - pubmed
Validity and reproducibility of a new diagnostic motor performance test in children with suspected myopathy . - pubmed
Fifteen functional items were used to measure muscle strength and muscle endurance in 68 patients ( 47 males , 21 females ; mean age 7y 8mo , SD 2y 2mo ; range 4 to 11y ) , who had been referred to our specialist centre in the past 3 years on suspicion of myopathy . - pubmed
The motor performance test can improve diagnostic procedure in children suspected of having myopathy . - pubmed
Effects of intrauterine infection on the function of the corpora lutea formed after first postpartum ovulations in dairy cows . - pubmed
This study was carried out to determine the relationship between postpartum intrauterine infections , endocrine patterns and the function of corpora lutea formed following the first postpartum ovulations in dairy cows . - pubmed
The occurrence of moderate to heavy bacterial growth patterns and the repeated isolations of the similar organisms during postpartum suggests the persistence of uterine infections in SC cows . - pubmed
Increases in PGFM concentrations prior to luteolysis in SC cows were associated with moderate to heavy infection . - pubmed
The first outbreak of acute diarrhea due to a pandemic strain of Vibrio parahaemolyticus O3 : K6 in Kolkata , India . - pubmed
Patient characteristics including etiology of end stage renal disease , presenting symptoms , serum creatinine and postoperative followup were documented . - pubmed
RESULTS : All 20 patients presented after assessment for a febrile urinary tract infection , and 35 % had concurrent lower urinary tract dysfunction . - pubmed
Patients with lower urinary tract dysfunction presented significantly earlier and had a higher postoperative serum creatinine than those without lower urinary tract dysfunction ( 1.1 vs 1.7 years , p = 0.048 ) . - pubmed
Seven of 16 patients underwent followup voiding cystourethrogram , with 5 demonstrating resolution and 2 , both with lower urinary tract dysfunction , exhibiting persistent vesicoureteral reflux . - pubmed
At a mean followup of 3.6 years 25 % of patients experienced recurrent pyelonephritis , while 75 % were asymptomatic . - pubmed
One instance of anastomotic stricture occurred in a patient with lower urinary tract dysfunction . - pubmed
Patients with lower urinary tract dysfunction are likely to present earlier after transplantation than those without lower urinary tract dysfunction , and may have an increased risk of persistent vesicoureteral reflux and renal damage despite surgical correction . - pubmed
Phase II trial of dose - dense doxorubicin plus gemcitabine followed by paclitaxel plus carboplatin in patients with advanced urothelial carcinoma and impaired renal function . - pubmed
BACKGROUND : Cisplatin - based therapy is standard in patients with advanced urothelial carcinoma but a large proportion are ineligible due to renal impairment . - pubmed
METHODS : Patients with advanced urothelial carcinoma who were ineligible for cisplatin were eligible based on at least 1 of the following : 1 ) serum creatinine & gt;1.5 mg / dL ; 2 ) creatinine clearance of & gt;30 mL / min/1.73 m(2 ) and & lt;60 mL / min/1.73 m(2 ) ; and/or 3 ) prior nephrectomy . - pubmed
Myelosuppression was the major toxicity , with 28 % of patients experiencing grade 3 - 4 neutropenia ; there were only 2 ( 8 % ) episodes of febrile neutropenia . - pubmed
Grade & gt ; or = 3 nonhematologic toxicities were infrequent with the exception of grade & gt ; or = 3 thrombotic episodes in 4 ( 16 % ) patients . - pubmed
CONCLUSIONS : Dose - dense sequential chemotherapy is tolerable and active in patients with urothelial carcinoma and renal impairment . - pubmed
Prolonged disease - free survival is achievable in a subset of patients with primary unresectable disease or lymph - node only metastases treated with carboplatin - based therapy + /- surgical consolidation . - pubmed
Randomized trials are needed to define the optimal regimen in patients with advanced urothelial carcinoma and renal impairment . - pubmed
Vascular complications of supracondylar humeral fractures in children . - pubmed
The purpose of this study was to analyze the vascular complications of 24 children with supracondylar humeral fractures treated in two affiliated hospitals and to propose a management plan . - pubmed
BACKGROUND : Upon initial repair , most patients with anomalous origin of the left coronary artery from the pulmonary artery ( ALCAPA ) present with severely impaired ventricular function and mitral regurgitation . - pubmed
At final follow - up , 95.5 % of the patients presented with a LVEF greater than 0.50 , and 84.1 % with a mitral regurgitation less than grade 2 . - pubmed
CONCLUSIONS : In the majority of patients with ALCAPA , both ventricular function and mitral valve regurgitation normalize over time . - pubmed
[ Efficacy of injectable carbapenems for respiratory infections caused by Streptococcus pneumoniae and Haemophilus influenzae with Monte Carlo simulation ] . - pubmed
Streptococcus pneumoniae and Haemophilus influenzae are two major pathogens for respiratory tract infections , and those infections might cause critically ill patients . - pubmed
, while for immunocompromised hosts or infections by penicillin - resistant Streptococcus pneumoniae ( PRSP ) , PAPM / BP , 500 mg , b.i.d . - pubmed
As for the infections caused by H. - pubmed
In vitro fluoroquinolone susceptibility of Pseudomonas aeruginosa isolates from dogs with ulcerative keratitis . - pubmed
OBJECTIVE : To determine the in vitro fluoroquinolone susceptibility profiles of Pseudomonas aeruginosa isolates from dogs with ulcerative keratitis . - pubmed
aeruginosa isolates from dogs with ulcerative keratitis were collected during a 3 - year period . - pubmed
aeruginosa - associated ulcerative keratitis in dogs . - pubmed
aeruginosa isolates collected from dogs with ulcerative keratitis in this study , the likelihood of susceptibility to the fluoroquinolones evaluated was high . - pubmed
We report a case in which a patient presented with severe right lower abdominal pain associated with nausea and vomiting 3 days after termination of pregnancy . - pubmed
The infants during the first four months of life had the lowest risk for Plasmodium falciparum , R malariae and P. - pubmed
Because of the relative rarity of the disease - MCL represents 6 % of non - Hodgkin lymphoma - an obvious effort is needed to enroll patients on clinical trials . - pubmed
Effects of thalidomide in a mouse model of cerulein - induced acute pancreatitis . - pubmed
The aim of the present study was to assess the effects of thalidomide in a murine model of necrotizing acute pancreatitis . - pubmed
Necrotizing acute pancreatitis was induced in mice by intraperitoneal injection of cerulein ( hourly , x5 , 50 microg / kg ) ; in another group of animals , thalidomide was administered ( 200 mg / kg orally ) at 1 h after first cerulein injection . - pubmed
After 24 h , biochemical , histological , and immunohistochemical evidences of acute pancreatitis developed in all cerulein - treated mice . - pubmed
Therefore , thalidomide treatment attenuates the development of acute pancreatitis caused by cerulein in mice . - pubmed
Little is known about the effect of dietary carbohydrate , glycaemic index ( GI ) and glycaemic load ( GL ) on the risk of the metabolic syndrome , especially in populations with white rice as the staple food . - pubmed
METHODS : Several clinical trials and large - scale epidemiological studies have evaluated the efficacy and tolerability of sertindole in patients with schizophrenia . - pubmed
[ Value of transrectal FNA in the diagnosis of prostate cancer in elderly patients ] . - pubmed
OBJECTIVES : To identify if there is a group elderly patients with clinical suspicion of prostate cancer in which pathological confirmation may be unnecessary , and if prostatic transrectal fine needle aspiration ( FNA ) may be a useful diagnostic tool for old patients . - pubmed
RESULTS : In 35 patients ( 48.6 % ) cytological diagnosis was positive for prostatic adenocarcinoma , whereas in 37 cytology was negative for cancer . - pubmed
When histological confirmation of prostatic carcinoma is required in elderly patients , transrectal prostatic FNA is a valid alternative to transrectal biopsy , due to its excellent tolerance and low complication rate . - pubmed
METHODS : Two hundred patients referred for outpatient colorectal cancer screening were randomized to receive a single - dose of unlabeled lubiprostone ( 24 microg ) or placebo prior to a split - dose PEG - E bowel preparation without dietary restriction . - pubmed
Patients enrolled in the lubiprostone treatment arm rated the overall experience as more tolerable ( P 0.003 ) and complained of less abdominal bloating ( P 0.049 ) . - pubmed
A 37 - year - old man was admitted with cough and fever . - pubmed
Etiology of goiter in man ; new concepts . - pubmed
[ Lipid peroxidation and antiradical defense in patients after endosurgical cholelithiasis ] . - pubmed
We designed a prospective randomized trial of the two - incision THA versus the mini - posterior technique to determine whether patients having two - incision THA , when compared with patients having mini - posterior THA , had evidence of less muscle damage as reflected by changes in hip muscle strength after surgery , a less antalgic gait as reflected by changes in the single - leg stance time and walking velocity , and better hip function as reflected by changes in the hip moments during level walking and stair climbing as assessed by comprehensive gait analysis testing . - pubmed
We found no evidence that patients who had two - incision THA had less muscle damage , less antalgic gait , or better gait kinematics than patients who had mini - posterior THA . - pubmed
[ Results of low - vision rehabilitation in vision impaired patients ] . - pubmed
We report on low vision rehabilitation in 100 vision impaired patients . - pubmed
METHODS : Low vision rehabilitation was performed in 100 consecutive patients ( 61 % AMD , 23 % diabetic retinopathy , 16 % other diseases ) . - pubmed
RESULTS : In 62 patients with low vision fitted with a system for the far distance we reached an increase of the visual acuity of more than one line in 95 % . - pubmed
[ ' Rheumatoid arthritis ' in a Surinamese man : leprosy ] . - pubmed
Rheumatoid arthritis was diagnosed in a 65 - year - old man from Suriname , on the basis of clinical and radiological findings . - pubmed
Left ventricular diastolic mechanical dyssynchrony and associated clinical outcomes in children with dilated cardiomyopathy . - pubmed
METHODS AND RESULTS : We calculated a diastolic and systolic dyssynchrony index ( standard deviation of time to peak tissue early diastolic / systolic velocity in 12 left ventricular segments ) in 33 children with DCM and 46 control subjects . - pubmed
A threshold to diagnose diastolic dyssynchrony was determined , and cardiac function and clinical outcomes were compared between DCM patients with and without diastolic dyssynchrony . - pubmed
The diastolic dyssynchrony index was significantly higher in children with DCM than in control subjects ( 28.1+/-18.1 versus 9.1+/-3.8 ms , P<0.0001 ) . - pubmed
Patients who died or underwent transplantation had greater diastolic dyssynchrony ( diastolic dyssynchrony index 37.9+/-20.5 versus 22.1+/-13.8 ms , P=0.01 ) , and the rate of transplant - free survival appeared to be worse for DCM patients with diastolic dyssynchrony than for patients with synchronous DCM ( hazard ratio 2.98 , P=0.11 ; hazard ratio adjusted for disease duration 2.95 , P=0.17 ) . - pubmed
CONCLUSIONS : Left ventricular diastolic mechanical dyssynchrony is common in pediatric DCM , especially in patients who subsequently experience transplantation or death , and may be associated with a decreased length of transplantation - free survival . - pubmed
Open reduction and internal fixation compared to closed reduction and external fixation in distal radial fractures : a randomized study of 50 patients . - pubmed
METHODS : 50 patients with an unstable or comminute distal radius fracture were randomized to either closed reduction and bridging external fixation , or open reduction and internal fixation using the TriMed system . - pubmed
5 patients in the external fixation group were reoperated due to malunion , as compared to 1 in the internal fixation group . - pubmed
Insight in modulation of inflammation in response to diclofenac intervention : a human intervention study . - pubmed
BACKGROUND : Chronic systemic low - grade inflammation in obese subjects is associated with health complications including cardiovascular diseases , insulin resistance and diabetes . - pubmed
METHODS : To address this limitation , we used an integrative omics approach to characterize modulation of inflammation in overweight men during an intervention with the non - steroidal anti - inflammatory drug diclofenac . - pubmed
To assess the effectiveness of deformity correction and safety of the two major corrective spinal surgical procedures , 35 patients , aged 14 - 47 years , were placed into two groups according to procedures performed . - pubmed
What is the significance of solitary bony abnormalities on bone scintigrams of children with malignancy ? - pubmed
This investigation was undertaken to evaluate the significance of solitary bony abnormalities on bone scintigrams of children with known or suspected malignancy . - pubmed
A total of 215 bone scans were performed in 183 children in order to look for possible metastasis over a 10 - year period . - pubmed
Here , we examined the effect of diet - induced maternal obesity on hippocampal development and function in the mouse offspring . - pubmed
Radiotherapy in the treatment of patients with unresectable extrahepatic cholangiocarcinoma . - pubmed
We analyzed the role of definitive chemoradiotherapy for patients with nonmetastatic , locally advanced extrahepatic cholangiocarcinoma treated at a single institution . - pubmed
METHODS AND MATERIALS : This retrospective analysis included 37 patients who underwent external beam radiation therapy ( EBRT ) with concurrent chemotherapy and/or brachytherapy ( BT ) for locally advanced extrahepatic cholangiocarcinoma . - pubmed
Two patients were alive without evidence of recurrence at the time of analysis . - pubmed
Two patients lived beyond 5 years without evidence of recurrence . - pubmed
Age , gender , tumor location ( proximal vs. distal ) , histologic differentiation , EBRT dose ( & lt;= or & gt;50 Gy ) , EBRT planning method ( two - dimensional vs. three - dimensional ) , and chemotherapy were not associated with patient outcomes . - pubmed
CONCLUSIONS : Patients with locally advanced extrahepatic cholangiocarcinoma have poor survival . - pubmed
The majority of patients treated with EBRT had local control at the time of death , suggesting that symptoms due to the local tumor effect might be effectively controlled with radiation therapy , and EBRT is an important element of treatment . - pubmed
Patients with stress incontinence or urgency , local irritation , infection , distal stenosis or a neoplastic process have very similar symptoms . - pubmed
The Clone 13 ( Cl13 ) strain of lymphocytic choriomeningitis virus is widely studied as a model of chronic systemic viral infection . - pubmed
OBJECTIVES : The purpose of this analysis was to characterize the progression of coronary atherosclerosis in patients with concomitant peripheral arterial disease ( PAD ) . - pubmed
The impact of concomitant PAD on coronary atherosclerosis progression in patients with coronary artery disease has not been well established . - pubmed
METHODS : The burden and progression of coronary atherosclerosis was investigated in 3,479 patients with coronary artery disease with ( n = 216 ) and without ( n = 3,263 ) concomitant PAD who participated in 7 clinical trials that employed serial intravascular ultrasound imaging . - pubmed
RESULTS : Patients with PAD had a greater percent atheroma volume ( 40.4 + - 9.2 % vs. 38.5 + - 9.1 % , p = 0.002 ) and percentage of images containing calcium ( 35.1 + - 26.2 % vs. 29.6 + - 24.2 % , p = 0.002 ) , in association with smaller lumen volume ( 275.7 + - 101.6 mm(3 ) vs. 301.4 + - 110.3 mm(3 ) , p & lt ; 0.001 ) and vessel wall volume ( 467.7 + - 166.8 mm(3 ) vs. 492.9 + - 169.8 mm(3 ) , p = 0.01 ) . - pubmed
On serial evaluation , patients with PAD demonstrated greater progression of percent atheroma volume ( +0.58 + - 0.38 vs. +0.23 + - 0.3 % , p = 0.009 ) and total atheroma volume ( -0.17 + - 2.69 mm(3 ) vs. -2.05 + - 2.15 mm(3 ) , p = 0.03 ) and experienced more cardiovascular events ( 26.3 % vs. 19.8 % , p = 0.03 ) . - pubmed
CONCLUSIONS : Patients with concomitant PAD harbor more extensive and calcified coronary atherosclerosis , constrictive arterial remodeling , and greater disease progression . - pubmed
METHODS : This was a multicentre , randomized open - label study in which 418 patients with mild to moderate AKs were randomized into two treatment groups . - pubmed
In all , 180 patients with dorsal or plantar diabetic foot ulcers ( unhealed for & gt;=1 month ) were randomized to receive Hyalograft-3D autograft first and then Laserskin autograft after 2 weeks ( n = 90 ; treatment group ) or nonadherent paraffin gauze ( n = 90 ; control group ) . - pubmed
We analyzed treatment and outcomes of patients undergoing multimodal endoscopic treatment of early esophageal neoplasia at our institution . - pubmed
METHODS : Records of patients undergoing endoscopic treatment for esophageal low - grade intraepithelial neoplasia ( LGIN , n = 11 ) , high - grade intraepithelial neoplasia ( HGIN , n = 24 ) , or T1N0M0 neoplasia ( n = 10 ) , presenting between 2007 and 2009 , were reviewed . - pubmed
Neoplasia and intestinal metaplasia were eradicated in 87.2 % and 56.4 % of patients , respectively , while 15.4 % developed metachronous neoplasia . - pubmed
A minority of treated patients developed recurrent neoplasia , which is usually amenable to further endoscopic therapy . - pubmed
Finally new research on Cu - Se supplementation is necessary to better understand the risk of the animals to suffer from Se deficiency . - pubmed
BACKGROUND : Dengue is the most important human viral disease transmitted by arthropod vectors . - pubmed
Establishment of primary mouse lung adenocarcinoma cell culture . - pubmed
In this study , 2 out of 5 primary lung adenocarcinoma cultures derived from DNA repair - deficient mice were established and characterised using electron microscopy and immunostaining . - pubmed
All patients had surgical repair of a postinfarction ventricular septal rupture . - pubmed
RESULTS : Surgery for postinfarction ventricular septal rupture was carried out on 59 patients . - pubmed
In 54 % of patients , the ventricular septal rupture was anterior , and 75 % had concomitant coronary artery bypass grafting . - pubmed
MATERIAL AND METHODS : All patients with sinonasal malignancies ( n = 177 ) treated between 1996 and 2010 at the Department of Head and Neck Surgery , University of Bonn , Germany were analyzed retrospectively . - pubmed
Data on age , gender and incidence were available for all patients but other demographic data , treatment regimes and outcome were only analyzed for carcinomas . - pubmed
Interestingly , 64 % of patients with sinonasal carcinoma presented with locally advanced disease ( T3 - 4 ) but only 15 % displayed corresponding regional lymph node metastases . - pubmed
Infection is generally bacterial in nature . - pubmed
In high - risk prostate cancer patients , there is accumulating evidence that either dose escalation to the prostate or hypofractionation may improve outcome . - pubmed
Although investigational , this review discusses the challenging idea of WPRT in the context of hypofractionation for patients with high - risk prostate cancer . - pubmed
The use of endoscopic retrograde cholangiopancreatography for treating benign biliary strictures has become the standard of practice , with surgery and percutaneous therapy reserved for selected patients . - pubmed
OBJECTIVE : To explore the proliferation inhibition and apoptosis effects of polysaccharides extracts from Hedyotis diffusa ( PEHD ) on multiple myeloma ( MM ) cell line RPMI 8226 cells in vitro , so as to provide experimental theory for the clinical application in the treatment of MM . - pubmed
Quality of sleep in patients with Parkinson ' s disease . - pubmed
The most important aim of this study was to evaluate the sleep quality in patients with PD . - pubmed
METHODS : This case - control study was performed on patients with PD referred to the Neurology Clinic of our teaching hospital in 2011 . - pubmed
Thirty - four patients with PD and 34 healthy people as control group were enrolled in this study . - pubmed
Sleep quality of patients and control was evaluated by Parkinson ' s disease sleep scale ( PDSS ) questionnaire . - pubmed
RESULTS : The mean total PDSS score in patient group was 55.29 ( SD = 26.92 ) indicating moderate to severe sleep disturbances whereas , the mean total score in control group was 20.34 ( SD = 10.65 ) . - pubmed
CONCLUSIONS : Our study demonstrated that patients with PD experienced poorer nocturnal sleep quality than the control group . - pubmed
Hydatid disease is a parasitic infestation caused by the tapeworm Echinococcus granulosus . - pubmed
We successfully treated a 55 - year - old woman with primary peritoneal hydatidosis . - pubmed
The patient was managed by a combination of preoperative and postoperative antihelminthic therapy along with laparotomy , cyst deroofing , toileting and omentoplasty . - pubmed
A multicenter case - case control study for risk factors and outcomes of extensively drug - resistant Acinetobacter baumannii bacteremia . - pubmed
Case group 1 was defined as having infection due to XDR A. - pubmed
baumannii , and case group 2 was defined as having infection due to non - XDR A. - pubmed
Pitt bacteremia score ( adjusted odds ratio [ aOR ] , 2.570 [ 95 % confidence interval ( CI ) , 1.528 - 4.322 ] ) , central venous catheters ( CVCs ; aOR , 12.644 [ 95 % CI , 2.143 - 74.620 ] ) , use of carbapenems ( aOR , 54.391 [ 95 % CI , 3.869 - 764.674 ] ) , and piperacillin - tazobactam ( aOR , 55.035 [ 95 % CI , 4.803 - 630.613 ] ) were independently associated with XDR A. - pubmed
In case group 2 , Pitt bacteremia score ( aOR , 1.667 [ 95 % CI , 1.265 - 2.196 ] ) and third - generation cephalosporins ( aOR , 2.965 [ 95 % CI , 1.224 - 7.182 ] ) were independently associated with non - XDR A. - pubmed
Survivors received more active empirical therapy ( 16.7 % vs 9.6 % ; P = .157 ) , had fewer cases of XDR bacteremia ( 45.8 % vs 52.6 % ; P = .452 ) , and received higher median definitive polymyxin B doses ( 840,000 units vs 700,000 units ; P = .339 ) CONCLUSIONS : Use of CVC and broad spectrum antibiotics were unique risk factors of XDR A. - pubmed
The " Seroquel " Outcomes Study ( SOS ): Efficacy and tolerability of quetiapine in a long - term , naturalistic study of patients with schizophrenia . - pubmed
The " Seroquel " Outcomes Study ( SOS ) aimed to assess the efficacy and tolerability of quetiapine in patients with schizophrenia in the clinical practice setting . - pubmed
A 6 - month , non - comparative , open - label study in adults with schizophrenia in a standard care setting in Spain . - pubmed
Quetiapine was found to improve symptoms of schizophrenia , as indicated by a significant decrease in BPRS scores , and was well tolerated by patients in clinical practice . - pubmed
The aims of this prospective randomized study were to investigate the incidence of trigger finger in patient groups undergoing transverse carpal ligament releasing ( TCL ) or TCL together with distal forearm fascia releasing and to identify other factors that may have an effect of these conditions . - pubmed
CASE PRESENTATION : The proband is a 49 - year - old man who underwent cerebral MRI in his thirties for persistent haeadache and tingling in his left arm and leg and was diagnosed with multiple supratentorial cavernous angiomas . - pubmed
Almost 21 % of patients were bothered by an impaired gustatory ability and 50.5 % of patients were affected by their loss of olfaction . - pubmed
Frequent nasal discharge was reported in 20 % , frequent sneezing in 58.1 % , and nasal itching in 33.3 % of the laryngectomized patients . - pubmed
INTRODUCTION : Skin and soft tissue infections involve microbial invasion of the skin and underlying soft tissues and are estimated to affect 7 - 10 % of hospitalized patients worldwide . - pubmed
Patients in India , aged from 1 to 65 years old , suffering from mild to moderate bacterial skin infections including impetigo , secondarily infected wounds , folliculitis , infected atopic dermatitis , and furunculosis were randomly allocated to three treatment groups within the studies . - pubmed
All English language articles reporting on a minimum of five patients<=18 - years old , treated with flexible ureteroscopy and lasertripsy for stone disease were included . - pubmed
MATERIALS AND METHODS : Fourteen healthy volunteers were subjected to transient normobaric hypoxia in an air - conditioned chamber simulating an oxygen concentration of a height of up to 5500 meters . - pubmed
Long - term clinical outcome of patients who failed catheter ablation of atrial fibrillation . - pubmed
AIMS : Left atrial ablation fails to prevent symptomatic recurrences of atrial fibrillation ( AF ) in 20 - 30 % of patients up to 3 years of follow - up despite multiple procedures . - pubmed
METHODS AND RESULTS : In this multicentre study , 218 ( 34 % ) of 631 consecutive patients , who had undergone AF catheter ablation in the years 2001 - 11 for drug - refractory symptomatic AF , had symptomatic AF recurrences after 1.5 + - 0.6 procedures . - pubmed
At a mean of 5.1 + - 2.6 years since their last ablation , 82 ( 38 % ) patients improved , 103 ( 47 % ) remained unchanged and 33 ( 15 % ) worsened , but only 17 ( 8 % ) had such a severe impairment of their quality of life as to require atrioventricular junction ablation and pacing ( # 13 ) or cardiac surgery ( # 4 ) ; 22 ( 10 % ) patients had had adverse clinical events ( death in five , heart failure in five , stroke and transient ischaemic cerebral attack in four , severe haemorrhage in four , pacemaker or implantable cardioverter - defibrillator implantation in seven ) and 98 ( 45 % ) patients had developed permanent AF . - pubmed
Compared with patients without permanent AF , fewer patients with permanent AF improved ( 3 % vs. 66 % , P = 0.001 ) and more got worse ( 28 % vs. 5 % , P = 0.001 ) . - pubmed
CONCLUSION : More than 5 years after a failed AF ablation , a small minority of patients had such an impaired quality of life as to require non - pharmacological interventions . - pubmed
Permanent AF was more common in patients who had left atrial enlargement , history of persistent AF , longer follow - up , and had performed a single ablation procedure , thus hypothesizing that reablation could reduce the chronicization of arrhythmia . - pubmed
CASE PRESENTATION : We report a case of 24 - year - old man with idiopathic ventricular tachycardia from a single focus in the supravalvular left ventricular outflow tract with two extremely divergent breakouts observed during the ablation procedure . - pubmed
Effective global tuberculosis control is hindered by the need for prolonged chemotherapy which leads to poor patient compliance . - pubmed
Normal BALB / c mice were infected with DeltahspX or the wild type ( WT ) strain . - pubmed
Three weeks after infection , the mice were treated with rifampicin , isoniazid and pyrazinamide for 14 weeks followed by 8 weeks of hydrocortisone . - pubmed
Effects of pomegranate and pomegranate - apple blend juices on the growth characteristics of Alicyclobacillus acidoterrestris DSM 3922 type strain vegetative cells and spores . - pubmed
This study was designed to evaluate the prevalence and severity of CAD with the use of MDCT angiography in asymptomatic KT recipients . - pubmed
METHODS : From September 2011 to November 2013 , MDCT angiography was performed on 90 renal transplant recipients who had no pre - transplantation CAD history and stabilized post - transplantation renal function for 6 - 18 months . - pubmed
The relevance of this relationship was then confirmed in human primary tumours . - pubmed
The purpose of the present study was to compare heparin administration and activated clotted times ( ACTs ) for patients undergoing CA for AF treated with interrupted apixaban before the procedure with patients on uninterrupted warfarin . - pubmed
METHODS : Consecutive patients undergoing CA for AF treated with interrupted apixaban or uninterrupted warfarin were prospectively enrolled . - pubmed
Seventeen SLE patients ( 13 females , four males ) died at a median follow - up of 48 months . - pubmed
METHODS : We conducted a quasi - experimental study among overweight and obese school children enrolled in 7th and 8th grades in Sousse , Tunisia with two groups , intervention and control . - pubmed
The 1 - year intervention was based on promoting healthy eating and physical activity through a collective intervention for all recruited children and an individual intervention only for obese children who require intensive managing . - pubmed
Visceral fat percentage was used as a measure of the animals ' weight gain during the trial . - pubmed
INTRODUCTION : In patients with normal estimated renal function before robot - assisted partial nephrectomy ( RPN ) , there is still a risk for de Novo chronic kidney disease ( CKD ) . - pubmed
We assessed the role of dipstick spot proteinuria in risk stratifying patients for CKD progression . - pubmed
Proteinuric patients were compared with the remainder of the cohort with parametric comparisons for continuous and chi - squared analysis for categoric variables . - pubmed
RESULTS : We found 269 patients with eGFR & gt;60 preoperatively , of whom 57 ( 21 % ) had proteinuria preoperatively . - pubmed
CONCLUSIONS : Patients with proteinuria preoperatively , despite a normal eGFR , likely have intrinsic medicorenal disease . - pubmed
MATERIALS AND METHODS : Forty patients diagnosed with persistent AR or non - allergic rhinitis referred to Shafa Medical Center affiliated to Kerman University of Medical Sciences were included in this study and were randomly allocated to the intervention or control groups . - pubmed
Patients received an injection of 80 units BTA ( Dysport , Ipsen Ltd Company , UK ) at a concentration of 200 mU / ml in normal saline on four spots in each side of the nose and were followed for 12 weeks . - pubmed
CONCLUSION : Submucoperichondrial BTA injection can be considered an effective therapeutic option in patients with persistent AR and idiopathic rhinitis . - pubmed
MATERIALS AND METHODS : A total of 305 prospective melanoma patients undergoing sentinel node biopsy were compared with 616 retrospective control patients with clinically localized melanoma whom have not undergone sentinel node biopsy . - pubmed
RESULTS : Overall , there were no differences in relapse - free survival or cancer - specific survival between sentinel node biopsy patients and control patients . - pubmed
Male sentinel node biopsy patients had significantly higher relapse - free survival ( P = 0.021 ) and cancer - specific survival ( P = 0.024 ) than control patients . - pubmed
Cancer - specific survival rates at 5 years were 87.8 % in sentinel node biopsy patients and 85.2 % in controls overall with 88.3 % in male sentinel node biopsy patients and 80.6 % in male controls and 87.3 % in female sentinel node biopsy patients and 89.8 % in female controls . - pubmed
CONCLUSION : Sentinel node biopsy did not improve survival in melanoma patients overall . - pubmed
While females had no differences in survival , males had significantly improved relapse - free survival and cancer - specific survival following sentinel node biopsy . - pubmed
[ Arteriovenous malformations of the brain : personal experience with 121 patients treated with microsurgery ] . - pubmed
OBJECTIVES : This study was designed to indicate whether different fractions from Artemisia biennis hydroethanolic extract could provide cytoprotection against oxidative stress and apoptosis induced by doxorubicin ( DOX ) in rat pheochromocytoma cell line ( PC12 ) . - pubmed
For evaluation of the effect of fractions ( A - G ) on DOX - induced cytotoxicity , PC12 cells were pretreated for 24 hr with the A. - pubmed
Protective efficacy of folic acid and vitamin B12 against nicotine - induced toxicity in pancreatic islets of the rat . - pubmed
In this study , male Wister rats were treated with nicotine ( 3 mg / kg body weight/ day ) with or without supplementation of folic acid ( 36 mug / kg body weight / day ) or vitamin B12 ( 0.63 mug / kg body weight / day ) alone or in combination . - pubmed
The results revealed that nicotine induced prediabetes condition with subsequent damage to pancreatic islets in rats . - pubmed
These results suggest that supplementation of folic acid and vitamin B12 in combination may be a possible strategy of detoxification against nicotine - induced toxicity in pancreatic islets of the rat . - pubmed
Here we report such a tumor , measuring 3 cm in diameter , found in the parotid gland of an 81 - year - old man . - pubmed
Association of cardiac cachexia and atrial fibrillation in heart failure patients . - pubmed
BACKGROUND : Cachexia is a common complication in patients with advanced heart failure ( HF ) associated with inflammatory response activation . - pubmed
OBJECTIVES : Evaluate the association of cardiac cachexia and atrial fibrillation in heart failure patients . - pubmed
Subjects with congenital heart disease , cancer , HIV , drug use and other causes than HF were excluded . - pubmed
During follow - up 47.8 % of subjects developed CC and 17.27 % AF , this was significantly more frequent in cachectic patients CC ( 23 % vs 12.11 % , OR : 2.17 , 95 % CI : 1.19 - 4.01 , p=0.006 ) . - pubmed
INTRODUCTION : Coinfection with certain members of the Flaviviridae , such as Dengue Virus ( DV ) , West Nile Virus ( WNV ) Yellow Fever Virus ( YFV ) and most importantly , GBV - C have been documented to reduce HIV-1 viral load in vivo . - pubmed
Numerous studies strongly support the notion that persistent coinfection with non - pathogenic virus prolongs survival in HIV-1 infected individuals . - pubmed
CONCLUSION : We hypothesize that a recombinant GBV - C - based vector can be constructed which expresses several beneficial genetic motifs of the Flaviviridae without causing any side effects while stimulating a wide array of beneficial miRNAs that can more efficiently prevent HIV-1 infection . - pubmed
RESULTS : All 71 patients reported being incapable of any voluntary reaction during the shock of the application time . - pubmed
We assessed ampicillin ( ABPC ) concentrations of liver , kidney and skin at a 2 - day withdrawal period in ten male and ten female White Leghorn chickens fed the diet containing ABPC ( ABPC medicated feed 40 mg / kg body weight / day ) for a week . - pubmed
CASE SUMMARY : One case of duodenal IFP was described and the literature is reviewed with emphasis on the clinical and pathological features of IFP in children . - pubmed
A case of an IFP in the duodenum of a 13 - year - old girl , who presented with abdominal pain , weight loss , vomiting , and constipation . - pubmed
CONCLUSION : To our best of our knowledge , this is the fourth report of IFP in adolescents , the first in a female 's duodenum . - pubmed
More of the M.tb proteome needs to be screened to identify proteins that induce strong antibody responses in LTBI . - pubmed
BACKGROUND AND PURPOSE : Objective ambulatory activity during daily living has not been characterized for people with Parkinson disease prior to initiation of dopaminergic medication . - pubmed
Our goal was to characterize ambulatory activity based on average daily step count and examine determinants of step count in nonexercising people with de novo Parkinson disease . - pubmed
The pharmacodynamics of low and standard doses of ticagrelor in patients with end stage renal disease on hemodialysis . - pubmed
BACKGROUND : Patients with end - stage renal disease ( ESRD ) on maintenance hemodialysis ( HD ) respond poorly to clopidogrel . - pubmed
We assessed the utility of low - dose ticagrelor in ESRD patients on maintenance HD . - pubmed
CONCLUSIONS : Low - dose ticagrelor afforded greater platelet inhibition than did clopidogrel in ESRD patients on HD . - pubmed
All nomograms had higher calibration and much better net benefit than the scenarios in predicting patients with or without different zones prostate cancer . - pubmed
BACKGROUND : In Brazil , studies on animals and humans in mainland areas have shown that most strains of Toxoplasma gondii are pathogenic to mice and exhibit great genetic variability . - pubmed
gondii strains from one cat and three rats on Fernando de Noronha Island . - pubmed
Prospective Study of Cetuximab , Carboplatin , and Radiation Therapy for Patients With Locally Advanced Head and Neck Squamous Cell Cancer Unfit for Cisplatin . - pubmed
PURPOSE : To report on the outcomes of a novel treatment regimen for patients with locally advanced head and neck squamous cell carcinoma who were fit for curative treatment but not fit for cisplatin . - pubmed
METHODS AND MATERIALS : Single - arm phase 1/2 study of previously untreated patients with biopsy - proven SCC of the oropharynx , larynx , or hypopharynx . - pubmed
Propranolol treatment lowers blood pressure , reduces vascular inflammatory markers and improves endothelial function in obese mice . - pubmed
Therefore , autonomic blockade was demonstrated to reverse hypertension , endothelial dysfunction and IR in obese individuals . - pubmed
Body weight , systolic blood pressure ( SBP ) , plasma biochemical parameters and aortic endothelial function were analyzed in mice fed standard diet ( control group ) or a high fat diet ( HFD ) that were treated with vehicle ( water ) or propranolol ( 10mg / kg / day ) for 8weeks . - pubmed
A 55 - year - old man with syncopal episodes was found to have sinus bradycardia at a rate of 37 beats / min , an episode of nonsustained ventricular tachycardia , and left ventricular noncompaction cardiomyopathy . - pubmed
After pretreatment , the rats were subjected to 60 min of right middle cerebral artery occlusion ( MCAO ) . - pubmed
RESULTS : Administration of CBD ( 100 and 200 ng / rat ) caused a significant reduction in infarction , brain oedema , and BBB permeability compared with the vehicle - received group . - pubmed
Natural course of tonsillectomy pain : A prospective patient cohort study . - pubmed
After undergoing tonsillectomy , patients scored their pain using the visual analogue scale three times daily ( morning , midday , and evening ) for 2 weeks . - pubmed
Postoperative pain was less in children and adolescents ( & lt;=18years old ) than in adults ( & gt;18 years old ) ( EV=-0.81 , 95 % CI=-1.56 to -0.08 , P=0.031 ) . - pubmed
A patient was diagnosed with a ruptured 1.2 - cm subcortical AVM after presenting with intracerebral hemorrhage in the right frontal lobe and anterior basal ganglia . - pubmed
Echocardiographic Evaluation of the Right Atrial Area Index in Dogs with Pulmonary Hypertension . - pubmed
BACKGROUND : Right atrial area ( RAA ) is a prognostic factor in human patients with pulmonary arterial hypertension ( PAH ) . - pubmed
Reference intervals for RAA have been described in healthy dogs . - pubmed
ANIMALS : A total of 119 client - owned dogs , 48 dogs with PAH and 71 control dogs . - pubmed
RESULTS : The RAA index was higher in dogs with moderate PAH ( 13.3 cm2 /m2 ; range , 3.4 - 24.7 cm2 /m2 ) and severe PAH ( 12.1 cm2 /m2 ; range , 5.4 - 21.8 cm2 /m2 ) than in those with mild PAH ( 6.7 cm2 /m2 ; range , 4.8 - 10.7 cm2 /m2 ) or in controls ( 7.3 cm2 /m2 ; range , 4.2 - 10.2 cm2 /m2 ; P & lt ; 0.001 ) . - pubmed
The RAA index was higher ( P & lt ; 0.0001 ) in dogs with R - CHF ( 17.5 cm2 /m2 ; range , 12.7 - 24.7 cm2 /m2 ) compared to those without R - CHF ( 7.6 cm2 /m2 ; range , 4.4 - 19.4 cm2 /m2 ) . - pubmed
In dogs with PAH , severity of tricuspid regurgitation ( TR ) was the only independent predictor of RAA index based on multivariate analysis ( P & lt ; 0.02 ) . - pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : The RAA index can be used to evaluate right atrial size in dogs and may be more effective than TRPG in predicting R - CHF in dogs with PAH . - pubmed
The severity of TR is the main determinant of the RAA index in dogs with PAH . - pubmed
OBJECTIVES / HYPOTHESIS : To develop a prediction model that can accurately predict the chance of success following revision stapes surgery in patients with recurrent or persistent otosclerosis at 2- to 6 - months follow - up and to validate this model internally . - pubmed
MATERIAL AND METHOD : A retrospective study was performed of all patients who had a history of melanoma and underwent EBUS - TBNA to assess hilar or mediastinal lymphadenopathy for the presence of metastatic melanoma . - pubmed
RESULTS : Eight patients had been diagnosed with malignant melanoma in the past ( mean 54.4 months , range 18 to 115 months ) while in the other three this tumor was primarily diagnosed in the staging phase . - pubmed
Altered functional connectivity between sub - regions in the thalamus and cortex in schizophrenia patients measured by resting state BOLD fMRI at 7T. - pubmed
Design , Setting , and Participants : This multicenter cohort study conducted manual audits of medical records of 375 patients who underwent 1 of 3 urologic procedures ( transurethral resection of bladder tumor [ TURBT ] , transurethral resection of the prostate [ TURP ] , and ureteroscopy [ URS ] ) at 5 Veterans Health Administration facilities from January 1 , 2016 , to June 30 , 2017 . - pubmed
Ten or eleven days later , the rats began behavioral testing that included 10 sessions of tone - shock pairings . - pubmed
Early progression of Krabbe disease in patients with symptom onset between 0 and 5 months . - pubmed
The purpose of this prospective study was to describe the natural progression of early onset Krabbe disease in a large cohort of patients . - pubmed
METHODS : Patients with early onset Krabbe disease were prospectively evaluated between 1999 and 2018 . - pubmed
Results of nerve conduction studies showed that 100 % of patients developed peripheral neuropathy by 6 months of age . - pubmed
Seizure Susceptibility Correlates with Brain Injury in Male Mice Treated with Hypothermia after Neonatal Hypoxia - Ischemia . - pubmed
Neonatal seizures and subsequent chronic epilepsy are frequent in this patient population and current treatments are partially effective . - pubmed
Thus , there are sex - specific consequences of neonatal HI on flurothyl seizure susceptibility in a murine neonatal HI model . - pubmed
Effect of Mizagliflozin on Postprandial Plasma Glucose in Patients With Functional Constipation . - pubmed
In this study , we intended to apply melatonin in melatonin - deficient mice to ascertain whether melatonin could reduce the incidence / severity of scoliosis , and investigate the role of melatonin on bone mineral density in scoliosis . - pubmed
All volunteers breathed dry air for vocal fold dehydration . - pubmed
Results : Compounds 3a , 3o , 3s and 3 t , showed broad anti - kinetoplastid activity against all species and strains tested . - pubmed
Patients receiving RRT had higher preoperative Charlson Comorbidity Index values ( median , 5 vs 4 ; P=.03 ) , Model for End - Stage Liver Disease scores ( mean , 19.0 vs 14.5 ; P<.001 ) , right atrial pressure ( mean , 19.1 vs 13.4 mm Hg ; P<.001 ) , and estimated 24 - hour urine protein levels ( median , 357 vs 174 mg ; P<.001 ) and lower preoperative estimated glomerular filtration rate ( eGFR ) ( median , 43 vs 57 mL / min ; P<.001 ) and measured GFR using 125I - iothalamate clearance ( median , 33 vs 51 mL / min ; P=.001 ) than those who did not require RRT . - pubmed
Approximately 40 % of patients with eGFR less than 45 mL / min/1.73 m2 and 24 - hour urine protein level greater than 400 mg required RRT vs 6 % with eGFR greater than45 mL / min/1.73 m2 and without significant proteinuria . - pubmed
Candida glabrata is a problematic opportunistic pathogen that is associated with high mortality in invasive infection , as well as both intrinsic and rapidly acquired antifungal resistance . - pubmed
Efficacy of povidone - iodine against accidental tumor incision during nephron - sparing surgery : experimental study in patients with renal cell carcinoma . - pubmed
Therefore , we compared ultrastructural indexes of angiogenic process and capillary remodelling by transmission electron microscopy in 9 COPD patients and 7 SHS after 6 weeks of individualized moderate - intensity endurance training . - pubmed
We observed a capillary basement membrane thickening in COPD patients only ( p = 0.008 ) and abnormal variations of endothelial nucleus density in response to exercise training in these patients when compared to SHS ( p = 0.042 ) . - pubmed
COPD patients had significantly fewer occurrences of pericyte / endothelium interdigitations , a morphologic marker of capillary maturation , than SHS ( p = 0.014 ) , and significantly higher levels of F2 - IsoP ( p = 0.048 ) . - pubmed
This study is the first to show abnormal capillary remodelling and to reveal impairments during the whole process of angiogenesis ( capillary creation and maturation ) in COPD patients . - pubmed
For the first time , we assess the biodistribution and toxicity of unshelled CIS and partially zinc - alloyed CISZ QDs in a murine model . - pubmed
Impact of Sevoflurane Versus Propofol Anesthesia on Post - Operative Cognitive Dysfunction in Elderly Cancer Patients : A Double - Blinded Randomized Controlled Trial . - pubmed
We evaluated whether sevoflurane - based anesthesia increased the incidence of POCD and worsened prognosis compared to propofol - based anesthesia in elderly cancer patients . - pubmed
Comparison of Experimental Infection of Normal and Immunosuppressed Chickens with Mycoplasma gallisepticum . - pubmed
Four different models of infection of chickens with Mycoplasma gallisepticum ( MG ) were evaluated . - pubmed
Material and Methods : In this case - control study , 30 preeclampsia patients and 30 healthy pregnant women as control group were selected and matched for maternal age , gestational age , and BMI . - pubmed
In a recent review , we have suggested a neuroinvasive potential of severe acute respiratory syndrome coronavirus 2 ( SARS - CoV-2 ) and its possible role in the causation of acute respiratory failure of coronavirus disease 2019 ( COVID-19 ) patients ( J Med Viol doi : 10.1002 / jmv.25728 ) , based upon the clinical and experimental data available on the past SARS - CoV-1 and the recent SARS - CoV-2 pandemic . - pubmed
In addition , we also discuss the peculiar manifestations of respiratory failure in COVID-19 patients and the possible involvement of nervous system . - pubmed
RESULTS : The expression of miR-488 was reduced in OC , which was associated with poor clinical outcomes and prognosis in OC patients . - pubmed
However , there is a paucity of data regarding the safety and effectiveness of balloon aortic valvuloplasty ( BAV ) in children with AVS with LV dysfunction . - pubmed
Therefore , the aim of this study was to evaluate outcomes to establish the safety and effectiveness of BAV in children with AVS and LV dysfunction in improving LV function and survival . - pubmed
Methods A total of 160 BAVs were performed from 2004 to 2017 ; of these , 41 ( 25.6 % ) patients had LV dysfunction . - pubmed
Results Children who had undergone BAV for AVS and LV dysfunction within the age range of six to 192 months showed a significant reduction in peak - to - peak pressure gradient ( PPG ) from 73.5 + - 30 mmHg to 26.7 + - 6.7 mmHg and improvement in LVEF from 32.8 + - 11 % to 54.3 + - 12.7 % after 24 hours . - pubmed
Four patients died , all of whom had severe LV dysfunction - one died during the procedure and three died within six to 20 hours after successful BAV . - pubmed
Conclusion Patients with AVS who develop LV dysfunction deteriorate and die soon without treatment . - pubmed
Clinical characteristics and oncologic outcomes in patients with preoperative clinical T3 and T4 colon cancer who were staged as pathologic T3 . - pubmed
It is necessary to address the shortcomings of pathologic exams in the matter of the understaging of T4 colon cancer , and to reinforce the treatment for local control in patients with cT4 colon cancer . - pubmed
The patient did not experience recurrence during the follow - up period . - pubmed
OBJECTIVES : The aim of this study was to analyze mitral annulus ( MA ) dynamics using cardiac magnetic resonance ( CMR ) in patients with degenerative mitral insufficiency who underwent mitral valve repair ( MVR ) . - pubmed
METHODS : Mitral valve imaging was performed by CMR in twenty - nine patients with degenerative mitral insufficiency who underwent MVR between July 2014 and August 2016 , with quadrangular resection of the posterior leaflet without ring annuloplasty . - pubmed
Still , in PCOS women , treatment with metformin or TZDs not only modulates the lipid metabolism , but also improves the ovulation . - pubmed
Also , metformin with lifestyle interventions has positive effects on the metabolic and reproductive features of PCOS patients . - pubmed
The compound is evaluated both in impregnated cotton wound dressings and in a gel formulation against skin infections caused by Staphylococcus aureus and methicillin resistant S. - pubmed
The present work demonstrates that AMC-109 displays a significantly higher antibacterial activity with up to a seven - log reduction in bacterial loads compared to current clinical standard therapy ; Altargo cream ( 1 % retapamulin ) and Fucidin cream ( 2 % fusidic acid ) in the in vivo wound models . - pubmed
The lecithins of the primary hepatoma induced by 3 '- methyl-4 - dimethylaminoazobenzene ( DAB ) and host liver of rat were isolated , and the individual molecular species were estimated quantitatively by combined thin - layer and gaschromatographic analysis and specific enzymic hydrolysis . - pubmed
Immunofluorescence staining showed infection with respiratory syncytial virus ( RSV ) . - pubmed
[ Acute pericarditis caused by Rickettsia conori ] . - pubmed
A new case report of acute pericarditis due to Rickettsia conori , the seventh to be published in the French literature , highlights the following facts:--the widespread distribution of fievre boutonneuse , which is to be found in a wide strip around the Meditteranean basin;--the mechanism by which the pericardium is affected , which is probably auto - immune;--the criteria for the biological diagnosis of the Rickettsial diseases;--above all , the neccessity for prolonged antibiotic therapy , however apparently benign the disease may have seemed . - pubmed
We report an unusual case of hypoglycaemia , in which a pregnant woman with a Rh - negative problem and random blood glucose levels of less than 10 mg/100 ml was found to have no clinical symptoms of hypoglycaemia . - pubmed
[ Glycogenolysis indices in the skeletal muscles of rats with experimental rickets ] . - pubmed
Content of glycogen and lactic acid was decreased in sceletal muscles of growing male rats during the acute periof of experimental rachitis . - pubmed
Thirty - two patients with clinical evidence of anterior horn cell dysfunction are descirbed . - pubmed
During the period of follow - up ( 1 to 5 years ) none of the patients without bulbar dysfunction initially developed such symptoms . - pubmed
In all these patients electromyographic evidence of anterior horn cell disease was confirmed . - pubmed
Conspicuous absence of pyramidal signs , elevated plasma citrate , normal plasma pyruvate values and the extremely slow progression suggest that this group of patients are different from other varieties of anterior horn cell dysfunction previously described . - pubmed
[ The efficiency of surgical treatment of patients with malignant tumors of nasal cavity and paranasal sinuses ] . - pubmed
In the years 1966 - 80 , 96 patients with malignant tumors of nasal cavity and paranasal sinuses were surgically treated in the Department of Otolaryngology , Medical University in Cracow . - pubmed
[ Human cytomegalovirus -- biology and infection ] . - pubmed
These data confirm that women with ovarian carcinoma produce an abnormal amount of steroids . - pubmed
Thus the clinical application of steroids as tumor markers in unselected patients is limited . - pubmed
In 2 patients the cyst showed little change . - pubmed
This article deals with state of the art reconstruction and rehabilitation of the head and neck cancer patient who requires mandibular resection . - pubmed
II : Inhibitory effect of N , N , N - trimethylsphingosine on metastatic potential of murine B16 melanoma cell line through blocking of tumor cell - dependent platelet aggregation . - pubmed
We recently observed that N , N , N - trimethylsphingosine ( TMS ) and N , N - dimethylsphingosine ( DMS ) , but not sphingosine ( SPN ) , had an inhibitory effect ( via blocking of transmembrane signaling ) on the growth of various human tumor cell lines in vitro as well as in vivo in nu / nu mice ( K. Endo et al . - pubmed
Some authors have demonstrated that magnesium therapy reduces the mortality in AMI patients . - pubmed
After the patient 's diagnosis of adrenoleukodystrophy was confirmed , long - chain fatty acid levels were obtained on his 5 - year - old brother and his mother . - pubmed
Anaesthesia in malignant hyperthermia - susceptible patients without dantrolene prophylaxis : a report of 30 cases . - pubmed
We conclude that the prophylactic use of dantrolene is not necessary in patients suspected to be prone to MH if triggering agents are avoided and the patients are closely monitored . - pubmed
A prospective study of 0.1 sec and 0.2 sec duration argon laser trabeculoplasty was undertaken in 33 patients with chronic simple glaucoma . - pubmed
Psychogenic seizures in children and adolescents : outcome after diagnosis by ictal video and electroencephalographic recording . - pubmed
Psychogenic seizures in 21 nonepileptic children and adolescents , aged 8 to 18 ( mean 14.5 ) years , were recorded by means of video recording and electroencephalography . - pubmed
Fifteen patients had psychogenic seizures spontaneously during recording , and six had seizures in response to suggestion and intravenous saline injection . - pubmed
A case of septicaemia due to Aeromonas hydrophila . - pubmed
A case of Aeromonas hydrophila septicaemia is reported , arising from the use of leeches in an attempt to salvage a replanted arm . - pubmed
The myeloid body - formation is not directly correlated to human nephrotoxicity . - pubmed
Experimental induction of malignant lymphomas can be achieved in the cottontop tamarin by inoculation with Epstein - Barr ( EB ) virus . - pubmed
This system provides an animal model for assessing the efficacy of vaccine protection against the virus which is intended to reduce the incidence of human tumours associated with EB virus infection , namely endemic Burkitt ' s lymphoma and undifferentiated nasopharyngeal carcinoma . - pubmed
Demonstration in live chickens of the carrier state in infectious laryngotracheitis . - pubmed
Two separate groups of nine - week - old specific pathogen free cockerels maintained in isolation were infected with a field strain of infectious laryngotracheitis ( ILT ) virus , either by intratracheal or combined intranasal and supraconjunctival inoculation . - pubmed
[ Characteristics of cellular and humoral immunity in gynecological patients with severe forms of suppurative - septic diseases ] . - pubmed
Fourteen men with a mean duration of infertility greater than 3 years who had significant sperm immobilizing or sperm - agglutinating antibodies were studied . - pubmed
Using rats with tumor transplanted into the subcutaneous tissue , tumor resections done with either an ordinary scalpel or a laser scalpel were compared from the viewpoints of tumor recurrence and survival time . - pubmed
The concentration of HpD in the tumor tissue of WKA rats with DAB hepatic tumor was twice that in liver tissue . - pubmed
Thus , AVP contributes modestly to the elevation of arterial pressure caused mainly by neurogenic mechanisms in SAD rats during the early postoperative period . - pubmed
Tc-99 m RBCs should be the initial test in patients with GI bleeding . - pubmed
Some characteristics of the cyclophosphamide - induced immunopotentiating cells in the spleen of mice bearing a large MOPC-315 tumor . - pubmed
Riboflavin nutritional status of rats suffering from essential fatty acid deficiency . - pubmed
Acute toxicity in rats and mice exposed to hydrogen chloride gas and aerosols . - pubmed
[ Incidence , pathogenesis , and prevention of grass tetany in cattle . - pubmed
Acute and convalescent sera from human pneumonia patients from whom M. - pubmed
Lymph production during staphylococcic B enterotoxemia - induced shock in monkeys . - pubmed
[ Aspects of liver damage in human and experimental poisoning with tri - orthocresylphosphate ] . - pubmed
AMINO antagonizes the head twitch reaction induced by 5 - hydroxytryptophan in mice and tryptamine convulsions in rats . - pubmed
The hyperthermia induced by fenfluramine ( in rats at a high ambient temperature ) as well as the stimulation of the hind limb flexor reflex in spinal rats , induced by fenfluramine or LSD , are also inhibited . - pubmed
AMINO antagonizes the 5 - HT - induced increase in blood pressure in pithed rats . - pubmed
This is particularly odd considering that five of the seven women suffered serious gastrointestinal hemorrhage during one or more of their pregnancies . - pubmed
The five articles are reviewed , basic information regarding PXE is given , a case history is recorded , and the possibility that pregnancy favors the development of these complications in patients with PXE is discussed . - pubmed
Enzyme - linked immunosorbent assay ( ELISA ) as a diagnostic tool for Guatemalan onchocerciasis using a bovine filaria ( Onchocerca gutturosa ) antigen and blood samples collected on filter paper . - pubmed
They involve the quality of life for cancer patients , after initial curative treatments . - pubmed
A study of rheological determinants ( plasma viscosity , whole - blood viscosity , and erythrocyte deformability ) was made in 24 matched pairs of patients with homozygous sickle cell disease , with and without homozygous alpha - thalassaemia 2 . - pubmed
The effect of halothane anaesthesia on the foetal responses to acute haemorrhage was studied in chronically prepared ewes . - pubmed
Glycogen in pancreatic islets of steroid diabetic rats . - pubmed
In the islets of the rat pancreas , steroid diabetes induced by triamcinolon - acetonid leads to degranulation of the B cells and glycogen infiltration . - pubmed
A patient with an acute abdomen during pregnancy is reported . - pubmed
Patients aged 18 to 65 years with histologically proven breast cancer treated by surgery and without distant metastases were eligible for the study . - pubmed
One of 10 entered patients , 1 was not evaluated due to missing data on hematologic toxicity . - pubmed
None of the affected individuals have cardiac or ocular manifestations of the Marfan syndrome . - pubmed
When cells of HL 60 , as a human lymphoma , were cultured with thionsulfolipid , 61 % of the cell growth was inhibited at the concentration of 200 micrograms / ml . - pubmed
Sensation was normal in the scars of the donor areas in all but three patients . - pubmed
METHODS : In a retrospective study , we assessed the clinical presentation of 23 patients with one or more NCSE episodes , their medical history , EEG , and antiepileptic drug ( AED ) treatment . - pubmed
RESULTS : There was considerable overlap in clinical features of patients with complex partial SE ( CPSE ) and generalized nonconvulsive SE ( GNSE ) . - pubmed
The structure of the O - antigenic polysaccharide from a strain of Aeromonas caviae , isolated from the stools of a patient with diarrhoea , has been investigated . - pubmed
DHEA acetate ( 0.35 mol / kg body wt ) was injected intraperitoneally to one - half of the animals while the others were injected with corn oil vehicle . - pubmed
Pulmonary thromboembolism ( PTE ) was diagnosed in 22 patients at Saga Medical School between 1981 and 1994 . - pubmed
When enhanced CT was done during acute severe respiratory failure in 3 patients , pulmonary artery filling defects were found in all . - pubmed
CASE : Sarcoidosis of the genital tract occurred in a woman with a 16 - year history of pulmonary sarcoidosis . - pubmed
STUDY DESIGN : Neurodevelopmental tests including the Stanford - Binet Intelligence ( IQ ) scale and the Developmental Test of Visual Motor Integration ( VMI ) were administered to 32 children ( 26 months to 16 years of age ) with complex single ventricle . - pubmed
Children who had deep hypothermic circulatory arrest during a prior Norwood procedure tended to have a lower IQ score . - pubmed
Secondary abnormality of carnitine biosynthesis results from carnitine reabsorptional system defect in juvenile visceral steatosis mice . - pubmed
We characterized the L - carnitine transport system which is defective in the kidney of juvenile visceral steatosis ( JVS ) mice by using kidney slices and carnitine - related compounds , and evaluated the influence of the transport defect on the biosynthetic pathway of carnitine . - pubmed
It has been suggested that the presence of subdural hematoma in patients with severe head injury is associated with elevated intracranial pressure and higher mortality . - pubmed
Twenty - four hours after the injection , of the hematoma in the subdural space in rats produced an extensive zone of underlying ischemic damage but silicone oil did not . - pubmed
Progressive ataxia , myoclonic epilepsy and cerebellar apoptosis in cystatin B - deficient mice . - pubmed
HIV / AIDS is a serious problem in sub - Saharan Africa . - pubmed
The adult mammalian central nervous system ( CNS ) fails to regenerate its axons following injury . - pubmed
In unselected cell lines and probably also in human cancer , multiple mechanisms are redundantly present to defend the organism from the insults of drugs . - pubmed
[ Pharmacokinetics of fusidic acid in patients with seriously infected burns ] . - pubmed
The pharmacokinetics of fusidic acid ( FA ) were studied in 10 infected severe burns patients ( 35 + /- 5 yrs , 81 + /- 17 kg ) i.e. - pubmed
In the absence of impaired liver function , this is attributable to the known increase in hepatic clearances in burns patients and , to a certain extent , to the existence of translesional extra - hepatic clearance , which could contribute to the success of treatment . - pubmed
Effect of a new starch - free bread on metabolic control in NIDDM patients . - pubmed
All patients had well established non insulin - dependent diabetes mellitus . - pubmed
CONCLUSIONS : Substitution of ordinary bread with starch - free bread at breakfast causes significant improvements in blood glucose levels in NIDDM patients on both a short and long term basis . - pubmed
Abnormalities of skeletal muscles are frequently observed in patients with congestive heart failure . - pubmed
OBJECTIVES : We sought to determine whether abciximab therapy at the time of percutaneous coronary intervention ( PCI ) would favorably affect one - year mortality in patients with diabetes . - pubmed
The one - year mortality rate for patients with a clinical diagnosis of diabetes mellitus was compared with the rate for nondiabetic patients treated with either abciximab or placebo . - pubmed
RESULTS : In the 1,462 diabetic patients , abciximab decreased the mortality from 4.5 % to 2.5 % , p = 0.031 , and in the 5,072 nondiabetic patients , from 2.6 % to 1.9 % , p = 0.099 . - pubmed
In patients with the clinical syndrome of insulin resistance -- defined as diabetes , hypertension , and obesity -- mortality was reduced by abciximab treatment from 5.1 % to 2.3 % , p = 0.044 . - pubmed
CONCLUSIONS : Abciximab decreases the mortality of diabetic patients to the level of placebo - treated nondiabetic patients . - pubmed
This beneficial effect is noteworthy in those diabetic patients who are also hypertensive and obese and in diabetics undergoing multivessel intervention . - pubmed
Besides its potential role in reducing repeat intervention for stented diabetic patients , abciximab therapy should be strongly considered in diabetic patients undergoing PCI to improve their survival . - pubmed
HIV / AIDS case histories : diagnostic problems . - pubmed
Two inoculation routes were used to compare the ability of MT78 and PA68 to colonize the respiratory tract and to induce colibacillosis in chickens . - pubmed
Irrespective to the inoculation route , MT78 and PA68 showed similar abilities to induce macroscopic lesions in chickens , to provoke bacteremia , and to colonize the internal organs . - pubmed
METHODS : Hearing loss developed in the patient at age 4 , blindness at age 48 , and dystonia at age 57 . - pubmed
We find that 36 % of AD patients have elevated perceptual thresholds for left / right outward radial optic flow discrimination . - pubmed
This reveals global pattern perceptual deficits that affect most AD patients ( 85 % ) and some normal elderly subjects ( 21 % ) . - pubmed
Pancreas after kidney transplants in posturemic patients with type I diabetes mellitus . - pubmed
Pancreas after previous kidney ( PAK ) transplants are an attractive option for type 1 diabetic patients because of the short waiting time and use of living kidney donors . - pubmed
Effects of acute sleep restriction on behavior , sustained attention , and response inhibition in children . - pubmed
OBJECTIVE : To assess the influence of race on the treatment and survival of patients with distal esophageal cancer . - pubmed
RESULTS : Black patients with esophageal adenocarcinoma were less likely to undergo surgery ( OR , 0.54 ; 95 % CI , 0.30 - 0.96 ) but had similar odds of undergoing chemotherapy and radiation therapy . - pubmed
Black patients with squamous cell carcinoma ( SCC ) were less likely to undergo surgical resection ( OR , 0.45 ; 95 % CI , 0.29 - 0.70 ) , but were more likely to undergo radiation therapy ( OR , 1.72 ; 95 % CI , 1.21 - 2.47 ) and chemotherapy ( OR , 1.74 ; 95 % CI , 1.19 - 2.54 ) . - pubmed
Mortality was increased for black patients with SCC ( adjusted risk ratio 1.33 ; 95 % CI , 1.10 - 1.61 ) but not adenocarcinoma . - pubmed
Ruling out a neurological deficit in knock - out mice , both strains reacted similarly to novelty , to intraperitoneal saline , or to the administration of scopolamine ( 1 mg / kg ) , an anti - muscarinic agent . - pubmed
In conclusion , it was evidenced that more than 10 % of micromycete strains developing on incorrectly - preserved fruit , berries and vegetables , produce toxic secondary metabolites that pose a potential health hazard for people eating or handling the foodstuff . - pubmed
Clinical and psychosocial outcome of patients affected by panic disorder with or without agoraphobia : results from a naturalistic follow - up study . - pubmed
OBJECTIVE : A clinical and psychosocial follow - up study of a cohort of 85 patients affected by panic disorder ( PD ) with or without agoraphobia was performed an average of 40 months after initial observation and following a mean duration of illness of 8 years . - pubmed
METHODS : Eighty - five out of 130 patients affected by PDs with or without agoraphobia according to DSM - III R criteria , examined between 1990 and 1995 at an outpatient clinic were re - examined in 1997/1998 using the same standardized clinical evaluation performed on admission . - pubmed
CONCLUSIONS : The findings of the study are suggestive of a chronic illness with a significant impact on everyday quality of life of patients . - pubmed
Dermatologic and oral findings in a cohort of 47 patients with Papillon - Lefevre syndrome . - pubmed
In this group , 15 invasive lobular carcinomas were identified in 12 patients . - pubmed
CB interventions have been shown to reduce pain and improve psychosocial functioning in patients who have chronic illnesses , particularly chronically painful rheumatologic syndromes . - pubmed
[ Sexual difference in pancreatic diabetes in rats castrated at birth ] . - pubmed
It is widely accepted that this procedure is to be recommended only in patients with early stage tumours . - pubmed
[ VITAMIN B-12 ABSORPTION IN PATIENTS WITH GASTRIC CANCER AND FOLLOWING GASTRIC RESECTION ] . - pubmed
Galactorrhea - associated granulosa cell tumor in a child . - pubmed
Granulosa cell tumor of the ovary is a rare form of ovarian cancer in children . - pubmed
An 11 - year - old girl was admitted with complaints of galactorrhea and abdominal mass . - pubmed
The clinical , hormonal , and radiological findings and the therapy of galactorrhea associated with granulosa cell tumor in a child are discussed . - pubmed
Anne McLaren is one of the world 's foremost developmental biologists ; a leader in elucidating the principles of early mammalian development whose research has underpinned advances in reproductive medicine and the treatment of infertility . - pubmed
Anaemia induced by iron deficiency may cause a challenge concerns for pregnant women , babies and adolescent , primarily . - pubmed
This Ewing sarcoma animal model will be a useful tool for dissecting the molecular pathogenesis of Ewing sarcoma and provides rationale for the broader use of organ - specific progenitor cell populations for the study of human sarcoma . - pubmed
A total of 414 faecal specimens collected from diarrhoeic dogs and tested positive to CPV-2 were analysed by the MGB probe assays and by conventional methods ( haemagglutination inhibition with MAbs , PCR - RFLP and sequence analysis ) for prediction of the CPV-2 antigen specificity , with an overall agreement of 100 % . - pubmed
A 34 - year - old man with Darier - White disease : a case report and review of the literature . - pubmed
We report a case of a man with Darier - White disease followed by a review of the current literature on the pathogenesis , clinical features , diagnosis , and treatment of this cutaneous malady . - pubmed
Outcome of short - term antiepileptic treatment in patients with solitary cerebral cysticercus granuloma . - pubmed
A total of 206 subjects with new onset seizures with SCCG were randomized into two groups : group A ( 98 patients ) were treated for 6 months and group B ( 108 patients ) were treated for 2 years with AED therapy . - pubmed
RESULTS : Partial seizures with or without secondary generalization has been found to be the commonest manifestation occurring in 80.6 % of patients with SCCG . - pubmed
In patients having residual calcification , 42.2 % in group A and 21.7 % in group B had recurrence of seizures and the difference was statistically significant ( Z = 1.97 , P & lt ; 0.05 ) . - pubmed
Higher recurrence rate was observed in short - term therapy in patients having calcified lesions and may require long - term AED treatment . - pubmed
In the present study , we evaluated the CBO changes induced by bypass blood flow in patients with MD and non - MD during the peri - operative periods employing optical spectroscopy . - pubmed
Neutropenia developed in both groups inoculated with a BVDV isolate . - pubmed
Genetically modified mice models for Alzheimer ' s disease . - pubmed
Transgenic mice models for Alzheimer ' s disease ( AD ) are essential to the understanding of disease pathophysiology , develop robust behavioral models and predict outcomes from pharmacological interventions . - pubmed
Although Staphylococcus epidermidis is the most common pathogen involved , infections with Staphylococcus aureus lead to severe peritoneal damage and are often associated with a dramatic loss of mesothelial cells . - pubmed
However , even after prolonged infection , a high percentage of S. - pubmed
Cell death induced by S. - pubmed
In conclusion , our data indicate that mesothelial cell death might represent a major mechanism of S. - pubmed
MATERIAL AND METHODS : We retrospectively reviewed patients with a positive urine culture with or without clinical symptoms of urinary tract infection admitted to an intensive care unit . - pubmed
RESULTS : The growth of microorganisms was determined in urine of 82 ( 3.9 % ) patients : urinary tract infection in 64 ( 78 % ) and colonization in 18 ( 22 % ) patients . - pubmed
In our opinion endovascular therapy is a good therapeutic option for chronic mesenteric ischemia in high surgical risk patients , specially when dealing with stenotic injuries . - pubmed
The clinical value of multilevel soft tissue release in the management of dynamic and static limb deformities in cerebral palsy children . - pubmed
The present article attempts to define the clinical , functional and radiological indications for multilevel soft tissue release in the treatment of static and dynamic deformities in cerebral palsy children . - pubmed
By restoring muscular balance , surgical treatment influences the presence and extent of dynamic and static joint deformity in the CP child and improves the child 's general condition . - pubmed
PURPOSE : The primary objective of this study was to compare rates of urinary tract and soft tissue infections in critically ill burn patients before and following introduction of a Bowel Management System ( BMS ) . - pubmed
Critically ill burn patients using a BMS were matched with similar patients managed before introduction of the device based on gender , total body surface area burned , burn location , ventilation days , and hospital length of stay . - pubmed
Trisomies in humans , such as trisomy 21 , are due to the missegregation of one chromosome in the first meiotic division in the oocyte . - pubmed
Failure to respond to the surface of Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical malaria amongst African children . - pubmed
METHODS : Between 2003 and 2006 , 26 consecutive patients ( 7 cerebral palsy , 10 Duchenne muscular dystrophy , 5 spinal muscular atrophy and 4 others ) with neuromuscular scoliosis underwent posterior pedicle screw fixation for the deformity . - pubmed
CONCLUSION : Results indicate that in patients with neuromuscular scoliosis , acceptable amounts of curve correction can be achieved and maintained with posterior - only pedicle screw instrumentation without anterior release procedure . - pubmed
One - gram portions of chicken frankfurters were inoculated with 0.5 log CFU of a single strain ( ATCC 700408 ) of Salmonella Typhimurium DT104 . - pubmed
Spontaneous ovarian hyper stimulation syndrome and deep vein thrombosis in a non pregnant woman : case report . - pubmed
CASE : A 27 - year - old non pregnant woman with bilateral ovarian masses who had underwent laparotomy for suspicion of malignant tumor . - pubmed
CONCLUSION : The incidence of thromboembolism in women with OHSS is low and the typical finding is deep venous thrombosis in the neck area . - pubmed
Atlantic salmon smolts challenged intraperitoneally ( ip ) and by cohabitation with a highly virulent strain of infectious pancreatic necrosis virus showed strong activation of important immune genes in spleen , liver , head - kidney and gill measured by real - time quantitative PCR . - pubmed
Two boys with the clinical and radiographic picture of acute tropical pyomyositis of the short external rotators of the hip were treated surgically followed by parenteral antibiotics ( Figure 1 ) . - pubmed
Staphylococcus aureus is responsible for the infection in & gt;75 % of the cases . - pubmed
Five patients ( 3.7 % ) discontinued AST at a median of 13 months ( range , 6 - 18 months ) because of disease progression ( n = 1 ) , hot flashes ( n = 2 ) , fatigue ( n = 1 ) , and impotence ( n = 1 ) . - pubmed
After a median follow - up of 37.4 months ( range , 24 - 90 months ) , the highest Radiation Therapy Oncology Group - defined late urinary toxicities were Grade 0 in 47.8 % , Grade 1 in 38.1 % , Grade 2 in 7.5 % , and Grade 3 in 6.7 % of patients . - pubmed
Maximal late gastrointestinal toxicities were Grade 0 in 73.1 % , Grade 1 in 16.4 % , Grade 2 in 7.5 % , and Grade 3 in 2.9 % of patients . - pubmed
Heroin users are at high risk for HIV infection , but little is known about HIV risk in oxycodone users . - pubmed
Until recently , the optimal work - up of patients with stable coronary artery disease ( CAD ) was based on non - invasive functional tests . - pubmed
Current indications for CCTA include symptomatic patients with intermediate pre - test probability of CAD with altered ECG ( LBBB , repolarization abnormalities ) rendering stress tests useless or patients unable to achieve sustained stress effort , and patients with indeterminate or uninterpretable results on ischemic work - up . - pubmed
Alglucosidase alfa : Long term use in the treatment of patients with Pompe disease . - pubmed
W - Swiss mice 60 or more days old are more readily immunizable against rabies virus infection than 20 day old or younger mice ; this difference in immunizability with increasing age is most conspicuous when vaccination with virulent virus is followed by intracerebral test infection and least apparent when vaccination with avirulent virus is followed by intramuscular test infection . - pubmed
MRI was collected in 32 AD patients , 24 MCI subjects and 18 healthy controls ( HC ) . - pubmed
Nine out of 24 MCI subjects converted to AD after an average follow - up interval of 2.5 years . - pubmed
BACKGROUND : Human clear cell renal cell carcinoma ( CRCC ) remains resistant to therapies . - pubmed
METHOD : A total of 322 patients with acute myocardial infarction participated in this study within 48 hours of hospital admission . - pubmed
Patients completed the Brief Symptom Inventory to assess anxiety level . - pubmed
The administration of metoprolol did not eliminate this relationship , perhaps because patients did not receive a sufficient dose of metoprolol to counter the effect of anxiety . - pubmed
We report our own experience of a male patient with bladder perforation after an early instillation of a single dose of MMC . - pubmed
Flash frozen lung samples removed from two patients undergoing lung transplantation for severe COPD ( n=4 ) were compared to similar samples from an unused donor lung ( n=2 ) that served as a control . - pubmed
[ An elderly man with known heart failure admitted with cardiogenic shock ] . - pubmed
Intracranial meningioma in children : different from adult forms ? - pubmed
OBJECTIVE : Intracranial meningiomas are very rare in children , comprising only 0.4 to 4.1 % of pediatric tumors and only 1.5 to 1.8 % to all intracranial meningiomas . - pubmed
PATIENT AND METHODS : We conducted a retrospective study from June 1983 to June 2007 ; during this period 521 patients underwent surgery for primary meningioma at the Rabat Hospital , Department of Neurosurgery . - pubmed
In one patient a neurofibromatosis was associated . - pubmed
This inhibitory effect is DENV dose dependent , requires DENV replication , and takes place in DENV - infected DCs as early as 2 h after infection . - pubmed
METHODS : We reviewed 45 electroencephalograms of patients divided into two groups : those with benign childhood epilepsy with centrotemporal spikes ( BCECTS ) and symptomatic partial epilepsy ( SPE ) , following ILAE criteria ( 1989 ) . - pubmed
RESULTS : There was a predominance of horizontal dipole between patients with BCECTS compared with patients with SPE ; however , this difference was not statistically significant . - pubmed
The metastasectomy and timing of pulmonary metastases on the outcome of osteosarcoma patients . - pubmed
METHODS : Data was obtained retrospectively on all consecutive osteosarcoma patients from 1985 to 2005 in author 's institute . - pubmed
In addition , the patients presented with lung metastases had a worse prognosis as compared with those without initial lung metastases ( p = 0.0001 ) . - pubmed
Patients who had late metastases after complete chemotherapy had a better prognosis ; whereas those who had metastases identified at the initial presentation predicted a poor prognosis . - pubmed
Dengue is an acute emerging infectious disease transmitted by Aedes mosquitoes and has become a serious global public health problem . - pubmed
We report the case of a 69 - year - old asymptomatic woman who presented with the incidental diagnosis of a prominent , vascular , reddish tumor of the iris . - pubmed
The objective of this study was to use optical coherence tomography to determine if a subset of patients with multiple sclerosis exhibit primary retinal neuronopathy , in the absence of retrograde degeneration of the retinal nerve fibre layer and to ascertain if such patients may have any distinguishing clinical characteristics . - pubmed
We identified 50 patients with multiple sclerosis with predominantly macular thinning ( normal retinal nerve fibre - layer thickness with average macular thickness & lt ; 5th percentile ) , a previously undescribed optical coherence tomography defined phenotype in multiple sclerosis , and compared them with 48 patients with multiple sclerosis with normal optical coherence tomography findings , 48 patients with multiple sclerosis with abnormal optical coherence tomography findings ( typical for multiple sclerosis ) and 86 healthy controls . - pubmed
Utilizing a novel retinal segmentation protocol , we found that those with predominant macular thinning had significant thinning of both the inner and outer nuclear layers , when compared with other patients with multiple sclerosis ( P & lt ; 0.001 for both ) , with relative sparing of the ganglion cell layer . - pubmed
Inner and outer nuclear layer thicknesses in patients with non - macular thinning predominant multiple sclerosis were not different from healthy controls . - pubmed
Functional corroboration of retinal dysfunction was provided through multi - focal electroretinography in a subset of such patients . - pubmed
These findings support the possibility of primary retinal pathology in a subset of patients with multiple sclerosis . - pubmed
Multiple sclerosis - severity scores were also significantly increased in patients with the macular thinning predominant phenotype , compared with those without this phenotype ( n = 96 , P=0.006 ) . - pubmed
We have identified a unique subset of patients with multiple sclerosis in whom there appears to be disproportionate thinning of the inner and outer nuclear layers , which may be occurring as a primary process independent of optic nerve pathology . - pubmed
Patients with inner and outer nuclear layer pathology have more rapid disability progression and thus retinal neuronal pathology may be a harbinger of a more aggressive form of multiple sclerosis . - pubmed
[ Hypothesis for the formation of human unresponsiveness to immunodeficiency virus ] . - pubmed
Particular emphasis is laid on human immunodeficiency virus ( HIV-1 ) , its origin theory , the time and site of its primary manifestations . - pubmed
INTRODUCTION : Hyperoxia has recently been reported as an independent risk factor for mortality in patients resuscitated from cardiac arrest . - pubmed
We examined the independent relationship between hyperoxia and outcomes in such patients . - pubmed
METHODS : We divided patients resuscitated from nontraumatic cardiac arrest from 125 intensive care units ( ICUs ) into three groups according to worst PaO2 level or alveolar - arterial O2 gradient in the first 24 hours after admission . - pubmed
RESULTS : Of 12,108 total patients , 1,285 ( 10.6 % ) had hyperoxia , 8,904 ( 73.5 % ) had hypoxia / poor O2 transfer , 1,919 ( 15.9 % ) had normoxia and 1,168 ( 9.7 % ) had isolated hypoxemia ( PaO2 & lt ; 60 mmHg ) . - pubmed
METHODS : Two hundred ninety - one patients with type 2 diabetes and significant depressive symptoms ( Beck Depression Inventory scores & gt;= 14 ) were recruited from a community - based , university - based , and Veterans Affairs health care systems . - pubmed
Intervention patients had significantly greater increases in step counts ( mean difference , 1131 steps / d ; P=0.0002 ) and greater reductions in depressive symptoms ( 58 % remitted at 12 mo vs. 39 % ; P=0.002 ) . - pubmed
Environmental enrichment rescues postnatal neurogenesis defect in the male and female Ts65Dn mouse model of Down syndrome . - pubmed
Impaired neurogenesis in the neocortex , hippocampus and cerebellum is believed to be the underlying cause of learning and behavioral deficits in the Ts65Dn mouse model of DS . - pubmed
Here , using the Ts65Dn mouse model of DS , we demonstrate that a combination of environmental enrichment and physical exercise starting in juvenile mice ( postnatal day 18 ) markedly increases cell proliferation , neurogenesis and gliogenesis in the hippocampal dentate gyrus ( DG ) and the forebrain subventricular zone ( SVZ ) of both male and female mice . - pubmed
Long - term evaluation of safety and health - related quality of life in women with heavy menstrual bleeding treated with oral tranexamic acid . - pubmed
AIMS : A multicenter , long - term , open - label study was conducted to assess the safety and health - related quality of life ( HRQoL ) of an oral tranexamic acid ( TA ) formulation in women with cyclic heavy menstrual bleeding ( HMB ) . - pubmed
The most commonly reported TEAEs among women in the intent - to - treat population ( n = 723 ) were headache , menstrual discomfort and back pain . - pubmed
Thirty - nine human breast cancer cell lines were also included in this study . - pubmed
At 24 hours after administration , documented erythema was seen around the injection site in a dose - dependent manner , particularly in all adults with MSU dose & gt;=200 mug . - pubmed
Among four Hepatitis C Virus ( HCV ) infected patients , three subjects were injection users and Human Immunodeficiency Virus ( HIV ) also infected two of them . - pubmed
Intra - amniotic administration of E coli lipopolysaccharides causes sustained inflammation of the fetal skin in sheep . - pubmed
At diagnosis , 73 % of the total 22 patients had nerve function impairment ( NFI ) . - pubmed
Autonomic function ( chi(2)= 5.5 , P= 0.019 ) and NCS ( chi(2)= 7.765 , P= 0.01 ) were significantly more altered in MB than PB patients . - pubmed
A high prevalence of neuropathy was observed in newly diagnosed patients . - pubmed
Cystic fibrosis ( CF ) patients are suffering from multiple often chronic endobronchial infection . - pubmed
While current standard of treatment of ABPA in CF patients is to suppress the allergy related symptoms by administration of glucocorticoids , itraconazole ( ITRA ) , administered orally at high doses , can alleviate the symptoms of ABPA . - pubmed
The data indicate that ITRA nanosuspension represents an interesting formulation for inhaled administration in CF patients suffering from ABPA . - pubmed
Molecular diagnosis of echovirus 30 as the etiological agent in an outbreak of aseptic meningitis in Panama : May - June 2008 . - pubmed
CONCLUSION : Echovirus 30 is reported as the likely cause of an outbreak of aseptic meningitis in Panama , the first since the 1980s . - pubmed
As more effective systemic therapy is being used in patients with solid tumors , patients with cancer live longer and are ultimately at higher risk for CNS metastases . - pubmed
After the induction of pulmonary inflammation and fibrosis via intratracheal delivery of bleomycin sulfate , mice were i.v . - pubmed
METHODS : Male Wistar rats were assigned into seven groups ( six in each ): intact ( control ) ; sham - operated ; nontreated rats subjected to ischemia and reperfusion ( IR ) ; ramiprilat - treated rats with ( Ram+IR ) and without ischemia ( Ram ) ; losartan treated with ( Los+IR ) and without ischemia ( Los ) . - pubmed
METHODS : From May 2010 to November 2011 , 61 patients treated for 74 metastases were included in the study . - pubmed
Patients responding to the treatment at d8 had a significative longer pain relapse free survival ( PRFS ) compared to patients not responding ( 3.38 weeks vs 0.3 weeks ; p & lt ; 0.001 ) . - pubmed
BACKGROUND : Active surveillance , followed by delayed definitive treatment for those who develop evidence of significant cancer progression , is now a recognised management strategy for selected men with low risk prostate cancer . - pubmed
Prostate carcinoma ( PCa ) was detected in 75 patients in the first group ( 47.5 % ) and in eight of the second group ( 40.0 % ) . - pubmed
In the first group , PCa was detected with targeted biopsies alone in 18 patients ( 24 % ) , with nontargeted biopsies alone in 23 ( 30.7 % ) , and with both in 34 ( 45.3 % ) . - pubmed
Twenty - six patients ( 29.8 % ) were diagnosed with malignant neoplasm . - pubmed
All patients with malignant LNs ( n = 5 ; 6.4 % ) were diagnosed with papillary carcinoma . - pubmed
CONCLUSIONS : In patients undergoing diagnostic hemithyroidectomies , routine level VI LND was able to identify LN metastases in 6.4 % of patients . - pubmed
Human cytomegalovirus ( HCMV ) , a betaherpesvirus , establishes latency in CD34(+ ) hematopoietic progenitor cells during natural infections in the body . - pubmed
Impact of left anterior line on left atrial appendage contractility in patients who underwent catheter ablation for chronic atrial fibrillation . - pubmed
METHODS : This study included 46 patients ( 30 men , mean age 58 + - 9 years , group 1 ) with persistent AF who underwent catheter ablation including LAL . - pubmed
Thirty patients with paroxysmal AF who received no additional LA ablation were compared as control group ( 21 males , mean age 56 + - 8 years , group 2 ) . - pubmed
In 8/11 patients , the first and second source of epileptic activity as found by DICS were concordant with the operative resection site ; these patients became seizure free after epilepsy surgery . - pubmed
[ The value of changes in end - tidal carbon dioxide pressure induced by passive leg raising test in predicting fluid responsiveness in mechanically ventilated patients with septic shock ] . - pubmed
OBJECTIVE : To test whether the changes of partial end - tidal carbon dioxide pressure ( PETCO2 ) during passive leg raising ( PLR ) predict fluid responsiveness in mechanically ventilated patients with septic shock . - pubmed
METHODS : Forty - two mechanically ventilated patients with septic shock admitted from January 2012 to November 2012 were prospectively recruited . - pubmed
CONCLUSIONS : The change of PETCO2 induced by passive leg raising is a non - invasive and easy way to predict fluid responsiveness in mechanically ventilated patients with septic shock . - pubmed
In the patients with catatonia , it is recommended to examine whether they have a general medical disease . - pubmed
We present two catatonic elder patients . - pubmed
In case of benzodiazepine resistance or malignant catatonia , it should be considered electroconvulsive therapy , but it needs to be carefully implemented for elder patients . - pubmed
Abscisic acid ( ABA ) inhibits the production of ethylene induced by water stress in excised wheat leaves and counteracts the stimulatory effect of 6 - benzyladenine ( BA ) on this process . - pubmed
The aim of the present prospective study was to investigate , in colorectal cancer patients , the relationship between preoperative tumour marker concentrations and various clinical variables . - pubmed
METHODS : The study prospectively enrolled 131 consecutive patients with a confirmed diagnosis of colorectal carcinoma and 131 age- and sex - matched control subjects with no malignancy . - pubmed
Levels of both tumour markers were significantly elevated in the presence of distant metastasis in the patient group ( p = 0.005 for cea ; p = 0.004 for ca 19 - 9 ) . - pubmed
CONCLUSIONS : Preoperative levels of cea and ca 19 - 9 might provide an estimate of lymph node invasion and distant metastasis in colorectal cancer patients . - pubmed
This report describes a case of lung cancer with sarcoid reaction following chemoradiotherapy , showing false - positive accumulation of ( 18 ) F - fluorodeoxyglucose on positron - emission tomography in a 55 - year - old man . - pubmed
BACKGROUND : Diabetic macular oedema ( DMO ) is the commonest cause of vision loss in people with diabetes . - pubmed
METHODS : We have used proteomic techniques to identify the protein changes induced by threshold intensity retinal laser treatment in a rodent model of diabetic retinopathy . - pubmed
Retinae were obtained from diabetic Dark Agouti rats 8 weeks following laser treatment . - pubmed
METHODS : This preliminary study utilized pre - symptomatic and post - symptomatic serum from a sample of 100 incident population - based US military veterans with MS along with 100 matched healthy controls . - pubmed
CONCLUSIONS : Compared with healthy controls , differential proteomic changes were noted in the serum of patients with MS that preceded the onset of symptomatic disease . - pubmed
Primary immunodeficiency disorders enable identification of genes with crucial roles in the human immune system . - pubmed
METHODS : As the initial cross - sectional analysis of a longitudinal study , we studied the association of brain volumes and somatic disease burden with neuropsychological outcomes , including measures of intelligence , memory , and attention in 20 patients with attenuated MPS II with a mean age of 15.8 . - pubmed
Normal age - related volume increases in white matter were not seen in MPS II patients as they were in controls . - pubmed
We investigated whether episodic hypotension is associated with tissue infarction in subjects with syncopal symptoms at stroke onset . - pubmed
Subjects with severe large vessel stenosis were excluded , while cases were referred for syncope unit investigation . - pubmed
RESULTS : thirty - eight of 772 stroke patients described presyncope or syncope at stroke onset and had patent large vessels ( 4.9 % of all strokes ) . - pubmed
Cases exhibited greater orthostatic BP drop than controls , P & lt ; 0.05 Twenty - four patients were diagnosed with vasovagal syncope through head - up tilt symptom reproduction , 9 with orthostatic hypotension , 4 with cardiac syncope and 1 with carotid sinus syndrome . - pubmed
Nineteen ( 50 % ) patients had an acute infarct on MRI , 14 of these were in the arterial borderzone ( 73.6 % ) . - pubmed
In children with congenital heart disease , tracheobronchial compromise is uncommon but potentially life - threatening . - pubmed
We present an overview of the etiologies of tracheobronchial lesions typically seen in children with congenital heart disease and review management options for these lesions . - pubmed
OBJECTIVE : To evaluate the detection of pituitary lesions at 7.0 T compared to 1.5 T MRI in 16 patients with clinically and biochemically proven Cushing ' s disease . - pubmed
CONCLUSION : The interobserver agreement of image assessment for 7.0 T MRI in patients with Cushing ' s disease was good , and lesions were detected more accurately with 7.0 T MRI . - pubmed
OBJECTIVES : The aim of this study was to find out potential relationships between serum , salivary and tissue protoporphyrin IX ( PX ) levels in subjects with or without oral precancerous and cancerous lesions . - pubmed
This study aimed to determine the susceptibility profile of Brazilian Brucella abortus isolates from cattle to eight antimicrobial agents that are recommended for the treatment of human brucellosis and to correlate the susceptibility patterns with origin , biotype and MLVA16 - genotype of the strains . - pubmed
abortus strains isolated from cattle in Brazil were sensitive to the antimicrobials commonly used for the treatment of human brucellosis ; however , a considerable proportion of strains showed reduced susceptibility to rifampicin and two strains were considered multidrug resistant . - pubmed
The patients were divided into 3 groups according to the World Health Organization body mass index ( BMI ) values : normal weight group ( BMI & lt;25 kg / m(2 ) ; group 1 ) , obese group ( BMI = 30 - 34 kg / m(2 ) ; group 2 ) , and severely obese group ( BMI & gt;=35 kg / m(2 ) ; group 3 ) . - pubmed
Overweight women ( BMI = 25 - 29 kg / m(2 ) ) were omitted . - pubmed
METHODS : This hospital - based case - control study included 120 NSCLC patients and 360 healthy controls . - pubmed
RESULTS : The expression of let-7c and miR-152 in plasma were found to be downregulated in the patients with NSCLC . - pubmed
CONCLUSION : It was found that let-7c and miR-152 are significantly reduced in plasma samples of NSCLC patients . - pubmed
These findings suggest that detection of circulating let-7c and miR-152 can be developed into a noninvasive and rapid diagnostic tool for the individuals with NSCLC . - pubmed
Thirty patients with precancerous or suspected malignant laryngeal lesions underwent microlaryngoscopy , during which samples were taken for cytological , immunocytochemical , and histological analysis . - pubmed
Our findings suggest that ARBs , as a class , are more effective than placebo therapy in long - term BP lowering in patients with essential hypertension . - pubmed
METHODS : One hundred and sixteen imaging studies of 94 patients ( CT n = 65 ; MRI n = 51 ) diagnosed with AE ( n = 55 ) or ICC ( n = 39 ) were retrospectively reviewed by two blinded radiologists for lesion features including enhancement pattern and matrix composition . - pubmed
POPULATION : One hundred and forty patients of both genders , mean age of 64.8 + -8.9 years , with knee osteoarthritis and chronic knee pain . - pubmed
BACKGROUND : There is a growing body of evidence linking micronutrient deficiencies and malaria incidence arising mostly from P. - pubmed
Close monitoring of the patient symptoms , ocular motility , intraocular pressure and the fundus showed no evidence of compressive optic neuropathy or perfusion abnormalities through orbital vessels . - pubmed
The first clinical trials of Zika virus vaccine candidates will begin in Q3/4 2016 but the pathway to licensure for a Zika virus vaccine is expected to take several years . - pubmed
We report a case of a 70 - year - old woman with generalized pustular psoriasis ( GPP ) who responded well to infliximab therapy and adalimumab therapy after secondary failure of infliximab therapy , but did not respond to ustekinumab therapy . - pubmed
BACKGROUND : Knowledge of hatha yogic exercises , the most used yoga style , for increasing functional capacity in patients with obstructive pulmonary diseases remains limited . - pubmed
POPULATION : Thirty - six patients with obstructive pulmonary disease . - pubmed
HY seems feasible and safe as a form of physical exercise for pulmonary disease patients . - pubmed
OBJECTIVE : People living with HIV ( PLWH ) have chronic immune activation and increased cardiovascular disease ( CVD ) risk . - pubmed
The aim of this study was to compare the anti - PD1 safety and efficacy in patients with previous severe toxicity to IPI versus in those showing moderate and no previous IPI - related AEs . - pubmed
METHODS : Fifty - six consecutive patients requiring reconstructive procedures following the extirpation of tumors were recruited . - pubmed
BACKGROUND : This study aimed at investigating the prevalence and risk factors of bovine thelaziosis , performed in the southeast of Iran , an endemic area for Iranian Sistani cattle . - pubmed
RESULTS : The overall prevalence for thelaziosis was 50 of 1924 cows ( 2 . - pubmed
The difference in the seasonal variations of prevalence and the intensity of infection were significant , however , no significant correlation between prevalence , sex and age of cattle was noted . - pubmed
CONCLUSION : Bovine thelaziosis needs special attention by veterinarians in the differential diagnosis of ocular manifestations and considering its impact on cattle production . - pubmed
Gram - negative bacteria are responsible for a large proportion of antimicrobial - resistant infections in humans and animals . - pubmed
MATERIAL AND METHODS : The study included patients with ischemic stroke which was confirmed clinically and by MRI ( n=1200 ) , the control group consisted of 500 patients without cardiovascular disease . - pubmed
Risk of myocardial infarction in patients with atrial fibrillation using vitamin K antagonists , aspirin or direct acting oral anticoagulants . - pubmed
AIM : Direct - acting oral anticoagulants ( DOACs ) have become available for the prevention of stroke in patients with atrial fibrillation ( AF ) . - pubmed
The objective of the present study was to evaluate the risk of AMI in patients with AF who are exposed to either VKAs , DOACs or low - dose ( & lt ; 325 mg ) aspirin . - pubmed
PURPOSE : Daytime complaints such as memory and attention deficits and failure to accomplish daily tasks are common in insomnia patients . - pubmed
The aim of this study was to investigate the hemodynamic response patterns of patients with chronic insomnia disorder ( CID ) using the noninvasive and low - cost functional neuroimaging technique of multichannel near - infrared spectroscopy ( NIRS ) in order to identify changes of neural function associated with cognitive performance . - pubmed
PATIENTS AND METHODS : Twenty - four CID patients and twenty - five healthy controls matched for age , right - hand dominance , educational level , and gender were examined during verbal fluency tasks ( VFT ) using NIRS . - pubmed
CID patients showed hypoactivation in the PFC during the cognitive task . - pubmed
Acquisition of Cholangiocarcinoma Traits during Advanced Hepatocellular Carcinoma Development in Mice . - pubmed
In this study , we investigated the potential acquisition of CC - like traits during advanced development of HCC in mice . - pubmed
Primary and rare high - grade HCC developed in a genetic mouse model . - pubmed
A mouse model of highly efficient HCC invasion and metastasis by orthotopic transplantation of liver cancer organoids propagated from primary tumors in the genetic model was further developed . - pubmed
Invasive / metastatic tumors developed in both models closely recapitulated advanced human HCC and displayed a striking acquisition of CC - related pathologic and molecular features , which was absent in the primary HCC tumors . - pubmed
- No Title - We are reporting the case of an 82 - year - old Yemeni patient , renal transplant recipient who was admitted to our institution and who subsequently developed disseminated infection with Saprochaete capitata . - pubmed
This is the second case to our knowledge of infection with Saprochaete capitata in a renal transplant patient . - pubmed
BACKGROUND : Focal radiation therapy has gained of interest in treatment of patients with primary prostate cancer ( PCa ) . - pubmed
OBJECTIVES : To examine ( 1 ) the effectiveness of therapeutic play in reducing anxiety and negative emotional manifestations among children undergoing cast - removal procedures and ( 2 ) the satisfaction of parents and cast technicians with cast - removal procedures . - pubmed
OUTCOME MEASURES : Children 's anxiety level , emotional manifestation and heart rate . - pubmed
RESULTS : Findings suggested that therapeutic play assists children aged 3 - 7 to reduce anxiety levels with mean differences between the intervention and control group was -20.1 ( 95 % CI -35.3 to -4.9 ; p=0.01 ) . - pubmed
CONCLUSION : Therapeutic play effectively reduces anxiety and negative emotional manifestations among children undergoing cast - removal procedures . - pubmed
He was a 12 - yr - old CH patient and treated with levothyroxine . - pubmed
The Efficacy of Amifostine against Multiple - Dose Doxorubicin - Induced Toxicity in Rats . - pubmed
Our results showed that amifostine successfully protected rats against multiple - dose doxorubicin - induced toxicity by complex , and still not fully elucidated mechanisms of action . - pubmed
Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease . - pubmed
This hypothesis has been supported by previous work in our laboratory , as evidenced by the perturbation of cytosolic protein solubility in response to amyloid plaques in a mouse model of Alzheimer ' s amyloidosis . - pubmed
In the current study , we demonstrate changes in proteome solubility are a common pathology to mouse models of neurodegenerative disease . - pubmed
Overall , our data suggest that neurodegenerative proteinopathies modeled in mice impose a burden on the proteostatic network that diminishes the ability of neural cells to prevent aberrant conformational changes that alter the solubility of hundreds of abundant cellular proteins . - pubmed
In vivo experiments using a mouse xenograft model revealed that combination therapy with NBT and ADR significantly reduced tumor volume by 84.15 % . - pubmed
It includes 36 patients suffering from different retinal pathologies including diabetic retinopathy , age related macular degeneration , and vitreomacular interface disorders using multicolor optical coherence tomography as a screening tool . - pubmed
Hemodynamic parameters were compared in AKI vs. no - AKI patients at the time of admission and 48 h thereafter . - pubmed
Exercise During Adolescence Attenuated Depressive - Like Behaviors and Hippocampal Mitochondrial Dysfunction Following Early Life Stress in Adult Male Rats . - pubmed
Maternal separation stress ( MS ) model to male rats ( postnatal day or PND2 - PND14 ) were performed to determination of depressive - like behaviors using the forced swimming test , splash test , and mitochondrial function in the hippocampus . - pubmed
METHODS : Adolescents aged 10 to 14 years with PFP were included ( N = 151 ) . - pubmed
CONCLUSION : A treatment strategy focusing on activity modification and load management was associated with high rates of successful outcome among adolescents with PFP at 12 and 52 weeks . - pubmed
BACKGROUND : Anger and stress can trigger episodes of atrial fibrillation ( AF ) in patients with a history of AF . - pubmed
METHODS : In this prospective , controlled , electronic diary - based study of emotions preceding AF , patients with a history of paroxysmal or persistent AF ( N = 91 ) recorded their rhythm on event monitors at the time of AF symptoms and completed a diary entry querying mood states ( eg , anger and stress ) for the preceding 30 minutes ( pre - AF " case period " ) for 1 year . - pubmed
A total of 163 symptomatic AF episodes ( in 34 patients ) and 11,563 Holter - confirmed sinus rhythm control periods had associated diary data . - pubmed
The Gram - negative bacterium Klebsiella pneumoniae is an opportunistic pathogen , which can cause life - threatening infections such as sepsis . - pubmed
Prognostic value of serial lactate levels in septic patients with and without shock . - pubmed
To analyze the prognostic value of lactate levels for day-7 and in - hospital mortality , in septic patients with and without shock . - pubmed
In the period November 2011 - December 2016 , we enrolled 268 patients , admitted to our High - Dependency Unit with a diagnosis of sepsis . - pubmed
Among patients with shock , an analysis for repeated measures confirmed a more marked lactate level reduction in survivors compared with non - survivors , both by day-7 and in - hospital mortality ( p = 0.057 and p = 0.006 ) . - pubmed
Complete response in patients with locally advanced rectal cancer after neoadjuvant treatment with nivolumab . - pubmed
In all , 88 patients with periodontitis and 79 healthy controls ( HCs ) were enrolled in the study . - pubmed
Novel therapies for hemophilia , including non - factor replacement and in vivo gene therapy , are showing promising results in the clinic , including for patients having a history of inhibitor development . - pubmed
When delivered as a protein to hemophilia A mice , a selected bi - paratopic sdAb significantly reduced the blood loss in a model of acute bleeding injury . - pubmed
We then packaged this sdAb in a hepatotropic AAV8 vector and tested its safety and efficacy profile in hemophilic mouse models . - pubmed
We show that the long - term expression of the bi - paratopic sdAb in the liver is safe and poorly immunogenic , and results in sustained correction of the bleeding phenotype in hemophilia A and B mice , even in the presence of inhibitory antibodies to the therapeutic clotting factor . - pubmed
Clinicopathological characteristics and prognostic factors for canine multicentric non - indolent T - cell lymphoma : 107 cases . - pubmed
The aim of this retrospective study was to determine outcomes and prognostic factors of 107 dogs with multicentric non - indolent T - cell lymphoma ( TCL ) receiving lomustine - based ( 70 % ) and non - lomustine - based ( 30 % ) treatment . - pubmed
Multicentric non - indolent TCL in dogs is an aggressive cancer with new possible prognostic factors . - pubmed
ANIMAL(S ): Nonobese diabetic ( NOD )/ severe combined immunodeficiency ( SCID ) female mice . - pubmed
Clinical characterization of status epilepticus in childhood : a retrospective study in 124 patients . - pubmed
We discuss culture , status , religion , and social influences , including insights into the complexities of cultural " blind spots " which complicate efforts by NGOs to improve working donkey welfare when the influence of different cultural and societal pressures are not recognized or acknowledged . - pubmed
BACKGROUND : This study will aim to assess the effectiveness of Mozart 's Music ( MM ) for the management of patients with drug - resistant epilepsy ( DRE ) . - pubmed
RESULTS : This study will summarize high quality randomized controlled trials to appraise the effectiveness and safety of MM for the treatment of patients with DRE . - pubmed
Postoperative complications and perioperative management in patients on hemodialysis undergoing lung resection . - pubmed
OBJECTIVES : The rate of lung resection in patients on hemodialysis ( HD ) is increasing with the increasing number of HD . - pubmed
The study aimed to investigate the perioperative management and postoperative complications of lung resection in HD patients . - pubmed
Thirty - eight patients had lung cancer . - pubmed
The reason for HD was diabetic nephropathy in 19 patients , nephrosclerosis in 10 , and miscellaneous in 14 . - pubmed
The frequency of bronchial calcification is relatively high in HD patients , and reinforcement of the calcified bronchial stump should be considered during lobectomy . - pubmed
Patients with abdominal wall masses as primary malignant tumours or metastatic disease are rare . - pubmed
We present a case series of three patients who presented with abdominal adenocarcinoma of unknown primary origin . - pubmed
All patients ultimately underwent surgical resection and final pathology showed a gynaecological origin for these tumours . - pubmed
Patient demographics , incidence and patterns of injury , outcomes , and ED resources use were evaluated as part of the study . - pubmed
BACKGROUND : A combination of central muscle relaxants , chlorzoxazone and baclofen ( chlorzoxazone - baclofen ) , has been proposed for treatment of cerebellar symptoms in human spinocerebellar ataxia . - pubmed
P elements were first discovered in the fruit fly Drosophila melanogaster as the causative agents of a syndrome of aberrant genetic traits called hybrid dysgenesis . - pubmed
METHODS : We retrospectively analyzed 207 patients who were hospitalized with SARS - CoV-2 pneumonia at the Self - Defense Forces Central Hospital in Tokyo , Japan . - pubmed
METHODS : Consecutive patients who underwent EMR for a LNPCP > = 20 mm were evaluated . - pubmed
METHODS : MR imaging was performed at 3 Tesla in 12 healthy subjects and 3 patients with various kidney pathologies ( fibrotic kidney disease , failed renal graft , and renal masses ) . - pubmed
Neonatal infection with mouse thymic virus : effects on cells regulating the antibody response to type III pneumococcal polysaccharide . - pubmed
Biosynthesis of different gangliosides in two types of rat ascites hepatoma cells with different degrees of cell adhesiveness . - pubmed
Since 1972 , 367 patients with chronic low - back pain have been treated by electrical stimulation ( e.s . ) - pubmed
Patients with herniated disc lesions and spondylitis and allied conditions were included . - pubmed
75 - 100 % pain relief was obtained by 53 % of the patients 50 % pain relief by 27 % and there was no improvement in 20 % of patients . - pubmed
In a follow - up of 208 patients , 6 - 36 months later , approximately 70 % stated that pain relief was similar to that obtained at the end of treatment . - pubmed
The present study examines the dose - response pattern of delta 9 - tetrahydrocannabinol self - injection in naive rats at 80 % reduced body weight and 100 % body weight , both conditions with a fixed - time 1 min ( FT-1 ) food delivery schedule . - pubmed
The results indicated that food deprived animals tested on a FT-1 min schedule self - injected low doses of delta 9 - THC at a higher rate than those animals at 100 % body weight and on a FT-1 min schedule . - pubmed
Animals at 80 % reduced body weight without a schedule did not differ from rats self - injecting delta 9 - THC at free feeding situation . - pubmed
These findings suggest that rats without previous history of drug dependence self - administer low doses of delta 9 - THC and that the interaction between the food deprivation state and the environmental contingencies introduced by a FT-1 min schedule is a critical variable in the acquisition period . - pubmed
[ Survival of 5 - fluorouracil - treated stomach cancer patients in the far - advanced stages ] . - pubmed
Umder study was the survival rate in 73 patients treated routinely with 5 - fluoruracil for recurrences and metastases of gastric cancer . - pubmed
The compared groups of patients did not differ reliably in such prognostic factors as the tumor spread to the onset of chemotherapy and duration of the interval since the primary operation till tumor progression . - pubmed
[ Cytophotometric determination of the DNA concentration of the nuclei of hepatocytes of rats trained to hypoxia ] . - pubmed
Computed tomographic scanning in patients with lymphoma . - pubmed
The spinal accessory - nerve - sparing operation is offered as an alternative to the classic procedure in all patients in whom the nerve is not directly invaded by cancer . - pubmed
A reversed rocket immunoelectrophoresis technique , applying serum samples to antigen - containing gel , is described for quantitation of human antibodies to diphtheria and tetanus . - pubmed
Because of the rarity of Darier ' s disease ( keratosis follicularis ) occurring as an acute , eruptive disease in a mature adult , a case with sudden onset in a 51 - year - old white man is reported . - pubmed
Physiologic effects of transfusing red blood cells with high or low affinity for oxygen to passively hyperventilated , anemic baboons : systemic and cerebral oxygen extraction . - pubmed
These findings lend support to the recommendation that preserved red cells with normal or elevated 2,3 DPG levels be administered to patients in hemorrhagic or septic shock , and to patients subjected to extracorporeal circulation during cardiac surgery in order to lessen the demand for increased blood flow and to ensure adequate tissue oxygenation during the postoperative period . - pubmed
Chronic renal disease and potassium depletion in cats . - pubmed
Renal tumours in male rats and those of liver in murine females had been described also after inhalatory exposure to unleaded gasoline . - pubmed
A reliable epidemiological study in occupationally gasoline exposed humans is still not available ( higher rate of tumours in workers of chemical petrol processing industry due to the influence of gasoline appears to be an indirect proof , because apart from gasoline also other substances are involved simultaneously ) . - pubmed
Pharmacological aspects of arthritis induced by a muramyl dipeptide analogue in rats . - pubmed
Bacterial ileocecitis caused by Escherichia coli O157 : H7 . - pubmed
Escherichia coli O157 : H7 is most commonly linked to hemorrhagic colitis and the hemolytic uremic syndrome . - pubmed
Diagnostic ultrasound was used to demonstrate terminal ileum abnormalities suggestive of bacterial ileocecitis , a recently described entity that resembles acute appendicitis , in a patient whose stool culture yielded E. - pubmed
A somatostatin analogue is protective against retrograde bile salt - induced pancreatitis in the rat . - pubmed
Phagocytic cells in middle ear effusion obtained from patients with acute or chronic otitis media , have antibacterial activity which is an element of the host defense system . - pubmed
The children with CMPI were divided into three groups according to clinical features : delayed - onset CMPI with gastrointestinal symptoms ( n = 8) ; immediate - onset CMPI with gastrointestinal and skin symptoms ( n = 8) ; and immediate - onset CMPI with skin symptoms only ( n = 8) . - pubmed
The CMPI groups were compared with children with untreated ( n = 9 ) or treated ( n = 8) coeliac disease and a control group ( n = 22 ) . - pubmed
Sera from the children were examined for cytotoxic effects using lymphocytes from healthy adults as effector cells and radiolabelled beta - lactoglobulin - coated erythrocytes from the same donor as target cells . - pubmed
Sera from children with CMPI and gastrointestinal symptomatology showed a significantly increased capacity to induce ADCC reactivity as compared with controls . - pubmed
In contrast , sera from children who had an immediate - onset CMPI with only skin symptoms mediated no such increase in ADCC reactivity . - pubmed
Twenty - seven patients had inoperable liver metastases of colorectal origin . - pubmed
Five / ten patients developed extrahepatic metastases . - pubmed
Ultrastructural , immunohistochemical , and cytogenetic study of a malignant peripheral neuroectodermal tumor in a patient seropositive for human immunodeficiency virus . - pubmed
[ Ultrastructural demonstration of the human papilloma virus ( HPV ) in oral proliferative lesions ] . - pubmed
The Human Papilloma Virus ( HPV ) has been found in a series of benign proliferative lesions of the skin and mucosa . - pubmed
The purpose of this report is to present a 5 - year experience of a prospective study on lymph node metastasis in patients with ovarian cancer through retroperitoneal lymphadenectomy at the Peking Union Medical College Hospital . - pubmed
A prospective randomized double blind investigation was made in 24 multiple injured patients . - pubmed
Acquired circulating anticoagulants in children with acquired immunodeficiency syndrome . - pubmed
As such , careful laboratory diagnosis of the cause of abnormal coagulation test results is necessary for children with AIDS . - pubmed
We compared two selected groups of patients with acute Guillain - Barre syndrome requiring artificial ventilation . - pubmed
Body weight change was decreased in rats . - pubmed
Morphologic changes in the kidneys with accompanying polyuria and hematuria / hemoglobinuria were observed in male rats . - pubmed
The only effect observed at 25 ppm was a low incidence of hematuria / hemoglobinuria in male rats . - pubmed
The immune response to A - Jax strain mouse organs in normal and A - Jax strain mouse liver tolerant rabbits . - pubmed
Tubular lesions produced by autoantibodies to tubular basement membrane in human renal allografts . - pubmed
Specific role of each human leukocyte type in viral infections . - pubmed
[ Isolation of mutant bacterial strains showing abnormal biosynthesis of the cell wall ] . - pubmed
[ Acute bacterial endocarditis due to Mima polymorpha ] . - pubmed
Concentration of phenylalanine in the blood serum of patients with various degrees of phenylketonuria . - pubmed
The data are discussed in view of their significance for therapy of patients with basal ganglia disorders , such as patients suffering from Parkinson ' s disease . - pubmed
Yield of unpredicted bone - marrow relapse diagnosed by routine marrow aspiration in children with acute lymphoblastic leukaemia . - pubmed
1466 children with acute lymphoblastic leukaemia had routine bone - marrow aspiration at the end of each 84 - day cycle of maintenance therapy . - pubmed
In the low - risk , moderate - risk , and high - risk leukaemic patients 0.4 % , 0.5 % , and 0.8 % , respectively , of the total routine bone - marrow aspirations yielded an unpredicted bone - marrow relapse . - pubmed
The median survival after relapse in the predicted group was significantly shorter than that in the unpredicted group , but the eventual outcome was the same in both groups , 95 % of all patients dying within 24 months of relapse . - pubmed
Salmonella strains sent for serotyping were inoculated into a tube with broth which was used as H antigen and , after heating also as O antigen . - pubmed
A quantitative anatomic study of 54 cardiac specimens with aortic atresia is related to surgical treatment of patients with aortic atresia and hypoplastic left heart syndrome . - pubmed
In the rat , ( phenylthio-4 phenylamino )- 2 nicotinic and [ ( chloro-4 phenylthio )- 4 phenylamino ]- 2 nicotinic acids inhibit the hypotensive prostaglandin - mediated action of arachidonic acid . - pubmed
The postmenopausal women with primary hyperparathyroidism had the B - ALP 4.30 + /- 0.54 mukat / l , the urinary hydroxyproline excretion 205.2 + /- 22.2 mmol / mol creatinine and urinary calcium excretion 8.9 + /- 0.5 mmol/24 hours , significantly increased in comparison with the group of women with menstrual cycle and primary hyperparathyroidism who had B - ALP 2.12 + /- 0.43 mukat / l , the urinary hydroxyproline excretion 119.0 + /- 14.9 mmol / mol creatinine and urinary calcium excretion 7.7 + /- 0.4 mmol/24 hours . - pubmed
Of 107 women investigated for frequency of micturition and dysuria , 21 had gonorrhoea , 14 chlamydial urethritis , eight an Escherichia coli urinary tract infection , 18 candidosis , 12 trichomoniasis , and four asymptomatic genital herpes . - pubmed
There were no differences in the distribution of T cell subsets between healthy volunteers and patients with active psoriasis . - pubmed
Squamous cell carcinoma of the skin subsequently developed in 2 of 3 PUVA - treated patients with the lowest percentages of T4 - bearing cells . - pubmed
Immunopathology of rhino mouse , an autosomal recessive mutant with murine lupus - like disease . - pubmed
Identifying the acutely ill patient with asthma . - pubmed
We studied 77 patients suffering acute asthma to identify those who needed hospitalization . - pubmed
Animal experiments have indicated that presbycardia as a distinctive entity does exist but that it does not , in and of itself , cause heart failure in large numbers of individuals . - pubmed
Diagnosis is altered in aged individuals because symptoms and signs may not be those classically described and taught . - pubmed
These patients were divided into 3 diagnostic categories : myofacial pain dysfunction syndrome ( MPD ) [ 18 ] , arthritis of the temporomandibular joints ( TMJ arthritis ) , and trigeminal neuralgia . - pubmed
They consisted of an normal , or non - patient group , a group of arthritis patients , and a group of movement disorder patients attending a neurology clinic . - pubmed
Among the facial pain patients and the normal controls few differences were found with regard to anhedonia and depression , The arthritis and neurology patients produced significantly higher depression and anhedonia scores than did several of the facial pain groups . - pubmed
Pain estimate ranged from 0 for control , to a mean of 67.6 + /- 31.3 for the trigeminal neuralgia patients with the MPD ( means = 56.2 + /- 32.5 ) and the TMJ arthritis patients ( means = 46.7 + /- 30.8 ) somewhat lower . - pubmed
In the present study of the brains from 18 patients who had died from Krabbe disease at 7 - 37 months of age , the concentration of galactosylceramide of cerebral and cerebellar white matter was severely reduced to 10 - 20 % of that in age - matched controls . - pubmed
We describe a case of necrotizing arteritis of the brain in a 26 - year - old man who presented as organic brain syndrome . - pubmed
OBJECTIVES : This study sought to assess the value of quantitative coronary arteriography in predicting an ischemic response at exercise echocardiography and technetium-99 m 2 - methoxy isobutyl isonitrile ( mibi ) single - photon emission computed tomography ( SPECT ) in patients with single - vessel disease of the left anterior descending coronary artery . - pubmed
BACKGROUND : The relation between severity of coronary stenosis and ischemic response to exercise echocardiography and perfusion scintigraphy in patients with single - vessel left anterior descending coronary artery disease is not well established . - pubmed
METHODS : Thirty - one patients without a previous myocardial infarction who had isolated stenosis of varying degrees in the proximal or midportion of the left anterior descending coronary artery were studied . - pubmed
Genetic studies in the nematode Caenorhabditis elegans and in the fruit fly Drosophila melanogaster have led to the isolation of genes that are specifically required for the induction of programmed cell death . - pubmed
METHODS : A critical prospective analysis of 121 patients , referred to two university centers after ESWL had been exhausted as a treatment modality for upper urinary tract calculi , was performed . - pubmed
Patients were subdivided into the following groups : failure to clear fragments , failure to fragment , difficulty in calculus localization , and failure due to inherent upper urinary tract obstruction . - pubmed
The frequency of elevated titers was 8.6 % in healthy subjects , 76.2 % in patients with untreated hyperthyroidism and diffuse goiter , 80.7 % in patients with relapse of hyperthyroidism . - pubmed
83.4 % of patient with hyperfunction changed spontaneously to hypothyroidism and 71.5 % of patients with hypothyroidism and goiter had antibodies above the normal range . - pubmed
Unexpectedly low prevalence of autoantibodies were detected in patients with primary myxoedema without goiter ( 48.2 % ) and in patients with endocrine ophthalmopathy and euthyroidism ( 33.2 % ) . - pubmed
In the subgroup of patients with hyperthyroidism under methimazole treatment we found an incidence of positivity of 56 % and the mean of positive values was lower compared with the untreated ones . - pubmed
In 42.8 % of patients with hyperthyroidism and diffuse goiter treated successfully by methimazole , surgery or radioiodine elevated concentrations of antibodies could be detected , however they were in remission for more than five years . - pubmed
However , nephrocalcinosis is noted in many children treated with this therapy . - pubmed
The management of long bone fractures in the head - injured polytrauma patient . - pubmed
The polytrauma patient who sustains a significant head injury ( head and neck Abbreviated Injury Scale of 3 or greater ) will require prolonged and technically demanding operative intervention for musculoskeletal and associated soft tissue trauma . - pubmed
The presence of a head injury may delay the immediate surgical intervention for long bone injuries , which has proven to have major advantages for patient care and well - being . - pubmed
This retrospective review of the Sunnybrook Health Science Centre experience between January 1 , 1986 , and June 1 , 1988 , identified 153 polytrauma patients with a significant head injury . - pubmed
The 88 patients treated operatively had 12 complications : one peroneal nerve palsy ; five cases of sepsis ( three in open fractures and all resolving with removal of fixation devices ) ; three malunions ; and three cases of delayed union . - pubmed
One patient had urinary retention . - pubmed
The ageing spontaneously hypertensive rat as a model of the transition from stable compensated hypertrophy to heart failure . - pubmed
Spontaneously hypertensive rats ( SHR ) of advanced age exhibit depressed myocardial contractile function and ventricular fibrosis , as stable compensated hypertrophy progresses to heart failure . - pubmed
Studies of papillary muscles from SHR with failing hearts ( SHR - F ) , SHR without failure ( SHR - NF ) , and age - matched Wistar Kyoto ( WKY ) rats allowed examination of changes in the mechanical properties of myocardium during the transition to heart failure . - pubmed
We cloned genes the expression of which is induced in the Mongolian gerbil ( Meriones unguiculatus ) hippocampus after transient forebrain ischemia by a differential display technique . - pubmed
To determine the effectiveness of posterior H - frame instrumentation for the surgical treatment of idiopathic scoliosis , 36 patients were studied . - pubmed
Pseudoarthrosis developed in one patient and imbalance in two patients . - pubmed
When compared to patients treated with supraglottic laryngectomy alone , irradiated patients had a significantly higher incidence of lifelong gastrostomy dependency ( 35 % versus 0 % ; p = .03 ) and acute upper airway obstruction ( 29 % versus 0 % ; p = .05 ) . - pubmed
There was a trend toward greater tracheotomy dependency ( 24 % versus 0 % ) , aspiration pneumonia ( 35 % versus 9 % ) , and delayed independent swallowing ( 34.8 weeks versus 7.8 weeks ) in the patients treated with combined therapy , but this difference was not significant . - pubmed
This should be considered when planning treatment for patients with supraglottic carcinoma . - pubmed
Among the volunteers , 73 % knew someone who may have had AIDS or knew someone who was at risk for acquiring HIV . - pubmed
Severely burned patients often present a hypercoagulability situation . - pubmed
Forty - three patients were studied on the first and seventh day after burn for hypercoagulability and fibrinolysis parameters . - pubmed
Severely burned patients show a state of transient disseminated intravascular coagulation , related to the development of organ failure and outcome . - pubmed
METHODS : Over the last 36 months , seven infants had a pleuroperitoneal shunt placed for the management of refractory chylothorax . - pubmed
RESULTS : All seven patients had excellent results with the elimination of the chylothorax and resolution of symptoms . - pubmed
Patient survival rate was five of seven ( 71 % ) with one infant dying of progressive pulmonary disease and one infant dying from viral sepsis ; both had functioning shunts . - pubmed
One patient remains ventilator dependent secondary to chronic lung disease from prematurity . - pubmed
These strains were previously identified as virulent ( induce diarrhea ) or attenuated ( no diarrhea ) in a gnotobiotic pig model of rotavirus infection [ Bohl et al . - pubmed
METHODS : For that purpose , a total of 30 chronic alcoholic patients , 10 without liver disease ( AWLD group ) and 20 diagnosed with alcoholic liver cirrhosis ( ALC ) were studied . - pubmed
Pregnancy aggravates proteinuria in subclinical glomerulonephritis in the rat . - pubmed
Because subclinical renal disease may be aggravated during pregnancy -- as reflected in the occurrence of proteinuria , for example -- we investigated whether a subclinical glomerulonephritis ( SG ) in the non - pregnant rat ( passive Heymann nephritis ) , a condition without proteinuria , is aggravated when the animals become pregnant and , if so , whether this is associated with a glomerular inflammatory reaction . - pubmed
SG was induced in non - pregnant rats 8 days before pregnancy . - pubmed
Experiment 1 revealed that non - pregnant rats with SG did not exhibit proteinuria . - pubmed
However , after the rats became pregnant , a significant proteinuria occurred , without an increase in systolic blood pressure . - pubmed
Experiment 2 revealed that the GFR did not increase in pregnant rats with SG , while experiment 3 showed that only pregnant animals exhibited a significant glomerular inflammation ; this glomerular inflammation was characterized by intraglomerular influx of polymorphonuclear cells and monocytes . - pubmed
Vaccination with DNA may provide a viable alternative or may be used in conjunction with protein - based subunit vaccines to maximize the efficacy of a human malaria vaccine that includes immunogenic regions of the SERA protein . - pubmed
All patients underwent surgical re - exploration 3 - 4 days after immunoscintigraphy ; the presence of tumour in the area of immunoscintigraphic uptake was evaluated in the biopsied material . - pubmed
A knock - out mouse for Canavan disease is being genetically engineered in our laboratory . - pubmed
Entacapone and selegiline with L - dopa in patients with Parkinson ' s disease : an interaction study . - pubmed
We studied clinical response , tolerability , haemodynamics and cardiac rhythm in 16 PD patients with end - of - dose - type motor fluctuations . - pubmed
One patient already had symptomatic orthostatism before experimental treatments ( control ) . - pubmed
In two other patients orthostatism emerged after the introduction of selegiline , and in one after every experimental treatment . - pubmed
One patient treated with entacapone+selegiline discontinued the study due to dizziness and insomnia . - pubmed
For that reason , xenon should be avoided in patients with increased cerebral pressure or cerebral perfusion disorders . - pubmed
Voacanga africana is used in Cameroonian ethnomedicine for the treatment of peptic ulcers . - pubmed
Treatment failure and death occurred in one patient ( 1.9 % ) . - pubmed
Three patients ( 5.7 % ) experienced relapses . - pubmed
There was a significant difference in total effective treatment time between patients with and without relapses ( 8.3 + /- 1.1 months vs 11.1 + /- 2.1 months ; p & lt ; 0.02 ) . - pubmed
A prospective study with different treatment durations is needed to determine the optimal treatment regimen for patients with INHr - TB . - pubmed
METHODS : Twenty six eyes ( 26 patients ) with optic disk pit maculopathy were treated with macular buckling procedure and evaluated with optical coherence tomography . - pubmed
In this investigation , 28 tendons ( 21 patients ) with a painful nodule located at the 2 - 6 cm level in the tendon , and 20 normal ( pain - free ) tendons , were examined with grey - scale ultrasonography combined with colour Doppler examination . - pubmed
Patients with a mediastinal tumor , neural or rhabdomyosarcomatous differentiation and distant metastases have the poorest prognosis . - pubmed
The author had elaborated the concept , claiming that the microangiopathy stage reflects the diabetes mellitus stage , basing on the sixteen - year experience of examination and treatment of 1100 patients with diabetic foot . - pubmed
[ Experimental portal hypertensive colopathy in rats with liver cirrhosis ] . - pubmed
To elucidate the morphological feature of portal hypertensive colopathy ( PHC ) , the macroscopic and microscopic vascular alterations of colonic mucosa was observed in rats with thioacetamide - induced liver cirrhosis . - pubmed
Histologic study revealed an increased in the number of the cross sections of venous vessels containing the colored lactices in the lamina propria mucosa(LP ) , lamina submucosal(SM ) and muscularis propria(MP ) in the cirrhotic rats . - pubmed
Stereoscopic results of the vascular cast obtained from the cirrhotic rats showed the presence of two characteristic vascular sings , i.e. - pubmed
In the clinical study , 38 patients with liver cirrhosis and 40 normal control received colonoscopic examinations . - pubmed
The vascular lesions similar to WT and VE were seen in 78.9 % and 65.8 % of cirrhotic patients , compared to 10.0 % and 7.5 % in the control . - pubmed
Since the cirrhotic rats used the present study were administered thioacetamide for only 12 weeks , it was suggested that PHC could occurred even in early stage of liver cirrhosis with mild portal hypertension . - pubmed
DESIGN : Awakenings were performed from SOREM ( REM at the onset of daytime naps and nighttime sleep ) and nighttime emergent ( ascending ) REM in 15 patients with narcolepsy and from nighttime REM in 9 normal healthy participants . - pubmed
PARTICIPANTS : Fifteen patients with narcolepsy , aged 17 to 70 years ( mean = 45.3 ) and 9 normal healthy subjects , aged 31 to 60 years ( mean = 43.0 ) . - pubmed
CONCLUSION : The REM sleep of patients with narcolepsy affords a unique opportunity to study emotion and to analyze its psychophysiology . - pubmed
Adult worms were also found in the middle ears of 2 cats showing purulent otitis . - pubmed
[ Effects of homologous and heterologous tumors on the growth and more especially the osseous development of young animals ] . - pubmed
Abnormalities of acetate metabolism in adrenal insufficiency in man . - pubmed
OBJECTIVE : In this study anxiety and depressive disorders were evaluated in patients admitted to an emergency department ( ED ) or to a medical department ( MD ) . - pubmed
The widespread use of eradication therapy for Helicobacter pylori has lead to an increase in antibiotic - resistant strains and the problem of retreatment in cases of eradication failure . - pubmed
The problem of schistosomiasis in Egypt has been complicated in recent years by the introduction of Biomphalaria glabrata , which has been reported to hybridize with B. - pubmed
A 61 - year - old female presented with a sudden onset of generalized tonic -- clonic convulsion . - pubmed
The volunteers were given 0.55 g ( 20 % ) ethanol / kg body weight as single dose about 4 hours after their breakfast meal , and on another occasion , 0.25 g fructose / kg body weight was used to sober the intoxicating effect produced by 0.55 g ( 20 % ) ethanol / kg body weight . - pubmed
Contact allergy to cinnamal in a patient with oral lichen planus . - pubmed
For & gt;15 generations , CD1 mice have been selectively and bidirectionally bred for either high - anxiety - related behavior ( HAB - M ) or low - anxiety - related behavior ( LAB - M ) on the elevated plus - maze . - pubmed
Furthermore , in both the forced - swim and tail - suspension tests , LAB - M animals showed lower scores of immobility than did HAB - M and NAB - M animals , indicative of a reduced depression - like behavior . - pubmed
BACKGROUND : Vagus nerve stimulation ( VNS ) had antidepressant effects in an initial open , acute phase pilot study of 59 participants in a treatment - resistant major depressive episode ( MDE ) . - pubmed
CONCLUSION : These results suggest that patients with chronic or recurrent , treatment - resistant depression may show long - term benefit when treated with VNS . - pubmed
BACKGROUND AND OBJECTIVES : The relationship between somatic and psychiatric comorbidity in patients with somatic diseases and diverse outcome variables like mortality , costs , and duration of treatment is often examined and confirmed . - pubmed
A previously published missense allele I515 T was found in the heterozygous state in an individual who was observed to be temperature sensitive for the auditory neuropathy phenotype . - pubmed
SAMPLE POPULATION : Samples of TBLF obtained from 11 calves with clinical signs of respiratory tract disease and growth of P multocida and Mycoplasma spp during culture of TBLF and samples of TBLF from 6 clinically normal calves with no bacterial growth during culture of TBLF . - pubmed
BACKGROUND : Respiratory syncytial virus ( RSV ) is associated with wheezing illness , and infections can occur repeatedly throughout life . - pubmed
These processes may be involved in decreasing T cell antiviral immune responses to RSV and in RSV - associated wheezing . - pubmed
METHODS : One hundred and eighteen patients ( 120 wrists ) who had been managed with the placement of an external fixation device for the treatment of a displaced , unstable , distal radial fracture were randomized into one of three treatment groups : ( 1 ) weekly dry dressing changes without pin - site care ; ( 2 ) daily pin - site care with a solution of one - half normal saline solution and one - half hydrogen peroxide ; and ( 3 ) treatment with the placement of chlorhexidine - impregnated discs ( Biopatch ) around the pins , with weekly changes of the discs by the treating surgeon . - pubmed
The patients were evaluated with regard to ( 1 ) erythema , ( 2 ) cellulitis , ( 3 ) drainage , ( 4 ) clinical or radiographic evidence of pin - loosening , ( 5 ) the need for antibiotics , and ( 6 ) the need for pin removal before fracture - healing due to infection . - pubmed
Twenty - three patients ( 19 % ) had a complication related to the pin track , with twelve of these patients requiring oral antibiotics for the treatment of a pin - track infection . - pubmed
Spinal cord injury - induced plasticity in the mouse -- the crossed phrenic phenomenon . - pubmed
Therefore , we explored whether it was possible to demonstrate the CPP in mice , a species amenable to a molecular genetic approach . - pubmed
Interestingly , our data also suggest that in the mouse latent fibers in the ventral funiculus ipsilateral to an anatomically incomplete hemisection may also play a role in the CPP . - pubmed
This is the first study to demonstrate the CPP in mice . - pubmed
Simkania negevensis and pneumonia in children . - pubmed
We herein report a first case of an infant with fetal warfarin syndrome in Thailand . - pubmed
The patient eventually died from respiratory failure at 6 months of age . - pubmed
Fasting glucose is not useful in identifying obese white children with impaired glucose tolerance . - pubmed
Animal models confirm that cell - mediated changes always follow structural failure caused by trauma . - pubmed
For the treatment of pain and irritation relief ( 21 patients , 22 eyes ) , all patients had complete or partial relief . - pubmed
We present two patients with reversible neurologic deficits after carotid artery stenting . - pubmed
There was no white matter edema or intracerebral hemorrhage in either patient . - pubmed
Cephalic ganglia appear smaller and disconnected in 1 - azakenpaullone - treated animals , whereas visual axons are ectopically projected , and the pharynx does not regenerate properly . - pubmed
The functional impact of early impairment was investigated by evaluating performance of everyday actions in older adults with mild AD ( n = 15 ) as compared with healthy age - matched controls ( n = 16 ) . - pubmed
The ability to form biofilm is seen as an increasingly important colonization strategy among both pathogenic and environmental Klebsiella pneumoniae strains . - pubmed
glucose is impaired in patients with type 2 diabetes mellitus compared with healthy individuals . - pubmed
Cardiopulmonary resuscitation feedback and debriefing may serve as a powerful tool to improve rescuer training and care for cardiac arrest patients . - pubmed
Fetal and neonatal nicotine exposure in Wistar rats causes progressive pancreatic mitochondrial damage and beta cell dysfunction . - pubmed
However , fetal and neonatal nicotine exposure in rats causes mitochondrial - mediated beta cell apoptosis at weaning , and adult - onset dysglycemia , which we hypothesize is related to progressive mitochondrial dysfunction in the pancreas . - pubmed
Importantly the appearance of these structural defects in nicotine - exposed animals preceded the onset of glucose intolerance . - pubmed
Taken together , these data suggest that maternal nicotine use during pregnancy results in postnatal mitochondrial dysfunction that may explain , in part , the dysglycemia observed in the offspring from this animal model . - pubmed
Our aim was to find out whether rhAPC dampens OA - induced ALI in sheep . - pubmed
The axonal lesion of TMBP - recipient mice resulted in lesion - specific recruitment of large numbers of T cells in contrast to very limited T - cell infiltration in TOVA - recipient and -naive perforant pathway - deafferented mice . - pubmed
METHODS : 14 men and 12 women aged 23 to 38 ( mean , 27 ) years with lateral ankle instability underwent the Brostrom procedure with a modified incision to repair both the anterior talofibular and calcaneofibular ligaments , without endangering the sural or superficial peroneal nerves . - pubmed
There was no apparent tissue toxicity in the murine peritoneum and the gel caused no adhesions . - pubmed
Neuronal migration disorders are often identified in patients with epilepsy refractory to medical treatment . - pubmed
The conditional mutant mice were viable , but exhibited complex neurological deficits including seizures , tremors , and growth retardation . - pubmed
Metronidazole resistance of feline Tritrichomonas foetus is presumed because of common treatment failure , and tinidazole does not consistently eradicate infection . - pubmed
Single T factors predict survival of patients with resected stage - IIB non - small - cell lung cancers . - pubmed
OBSERVATIONS : We discuss the mechanisms of oncogenicity , including genetic , environmental , and iatrogenic factors , in 2 patients with HHD , multiple primary melanomas , and other cancers . - pubmed
Patient 1 had a mucoepidermoid carcinoma of the parotid gland . - pubmed
CONCLUSIONS : The cause of the cancers in these 2 patients is likely multifactorial . - pubmed
As our understanding of the molecular alterations driving human cancer increases , there is an opportunity to direct the clinical application of cancer therapeutics with improved accuracy . - pubmed
Detection of circulating tumor cells in metastatic breast cancer patients . - pubmed
OBJECTIVE : The objective of this study was the detection of circulating tumor cells ( CTCs ) in metastatic breast cancer patients . - pubmed
Twenty eight patients with metastatic breast cancer were enrolled in the study and the control group consisted of 19 clinically healthy women . - pubmed
RESULTS : The positivity for CTCs was found in 20 ( 50.0 % ) patients with metastatic breast cancer patients , while in 6 ( 31.6 % ) healthy controls false positive circulating epithelial - like cells were detected . - pubmed
Sarcocystis calchasi - associated neurologic disease in a domestic pigeon in North America . - pubmed
Tissue cysts of a protozoan parasite were present in the skeletal muscle of a domestic pigeon ( Columba livia f. domestica ) with neurologic disease in Minnesota , USA . - pubmed
The animal had a severe granulomatous meningoencephalitis . - pubmed
A 72 - year - old man was admitted to our hospital because of dysphagia , and endoscopy showed a tumor in the esophagus . - pubmed
67 - year old man in a good physical condition was admitted to the Clinic to diagnose mediastinal tumor which was noticed on chest radiogram . - pubmed
METHODS : This was a population - based cohort study of patients who underwent gastrectomy for peptic ulcer disease between 1964 and 2008 in Sweden . - pubmed
Mechanisms of endothelial dysfunction in resistance arteries from patients with end - stage renal disease . - pubmed
Subcutaneous resistance arteries from 35 end - stage renal disease ( ESRD ) patients and 28 matched controls were studied ex - vivo . - pubmed
Spores from two distinct colony types of the strain Bacillus subtilis PB6 substantiate anti - inflammatory probiotic effects in mice . - pubmed
METHODS : The immunomodulatory potential of strain PB6 was first characterized in vitro on human immunocompetent cells for both the commercial spore powder ( Anaban ) and two phenotypic variants of the vegetative form . - pubmed
Assessment of the in vivo anti - inflammatory capacity of the standard spore powder and a variant spore powder preparation was performed using a mouse model of acute , TNBS - induced colitis . - pubmed
Hyperkalemia in predialysis patients . - pubmed
METHODS : We studied 32 ARDS patients with shock despite fluid loading , who were randomized to receive TP ( 16 patients ) or dopamine ( 16 patients ) . - pubmed
Previous studies are limited by small numbers of patients with specific forms of diffuse lung disease . - pubmed
RESULTS : There were 31 diffuse lung disease ( DLD ) , 57 cystic fibrosis ( CF ) , and 16 pulmonary vascular disease ( PVD ) patients included in our analysis . - pubmed
Patients with DLD had significantly higher pre - transplant morbidity including lower percent predicted of forced expiratory volume in first second ( P = 0.013 ) and more patients with pulmonary hypertension ( P = 0.001 ) and hypercapnia ( P = 0.031 ) . - pubmed
CONCLUSION : Lung transplantation is as successful for patients with end stage diffuse lung disease as compared to other lung transplant candidates . - pubmed
In addition , recent studies suggest that it may be useful in critically ill patients . - pubmed
There is significant difference in the transformation efficiency ( average number of days of hairy root induction ) and transformation frequency for all strains of A. - pubmed
However , the transformation frequencies of all five strains were below 30 % , with A. - pubmed
Percutaneous aortic valve implantation is an emergent technique alternative to surgical aortic valve replacement in high risk patients with aortic stenosis . - pubmed
Periods of nicotine withdrawal , in particular , may promote panic in individuals high in anxiety sensitivity . - pubmed
DESIGN : Open - label prospective cohort study of patients with GAVE refractory to APC . - pubmed
PATIENTS : GAVE patients with previous failed APC therapy , chronic anemia , and transfusion dependence . - pubmed
RESULTS : Twenty - one patients underwent at least 1 RFA session with ablation of GAVE lesions . - pubmed
Freund 's complete adjuvant was used to induce AA in rats . - pubmed
Secondary paw swelling , polyarthritis index , index of immune organs and histopathological assessment were used to evaluate the effects of TAHP on AA in rats . - pubmed
We explored the ability of an oral milk thistle extract formulation that was enriched with a water - soluble form of silibinin complexed with the amino - sugar meglumine to inhibit the growth of non - small - cell lung carcinoma ( NSCLC ) mouse xenografts . - pubmed
Bacterial contamination under fillings proved to be the main reason for pulp inflammation thus emphasizing the importance of antibacterial properties of restorative materials . - pubmed
Integrative ' omic ' approach towards understanding the nature of human diseases . - pubmed
The combination of improving technologies for molecular interrogation of global molecular alterations in human diseases along with increases in computational capacity , have enabled unprecedented insight into disease etiology , pathogenesis and have enabled new possibilities for biomarker development . - pubmed
We therefore propose a novel positional integratomic approach toward studying ' omic ' information in human disease . - pubmed
HBV - LC patients , especially the nonsurvival ones , manifested a profound decrease in the Treg / Th17 ratio , which was negatively correlated with Child - Pugh and model of end - stage liver disease scores . - pubmed
With improvements in medical and surgical care , overall survival of patients with SBS now exceeds 90 % . - pubmed
Acute caloric restriction improves glomerular filtration rate in patients with morbid obesity and type 2 diabetes . - pubmed
METHODS : Renal function , as measured by glomerular filtration rate ( GFR ) , was evaluated in 14 patients with type 2 diabetes mellitus , morbid obesity and stage 2 chronic kidney disease before and after a 7 - day very low - calory diet ( VLCD ) . - pubmed
Immunomodulatory effect of red onion ( Allium cepa Linn ) scale extract on experimentally induced atypical prostatic hyperplasia in Wistar rats . - pubmed
Atypical prostatic hyperplasia ( APH ) was induced in adult castrated Wistar rats by both s.c . - pubmed
The objective of this study was to review the efficacy of frovatriptan vs. other triptans , in the acute treatment of migraine in subgroups of subjects classified according to gender ( men vs. women ) through a pooled analysis of three individual randomized Italian studies . - pubmed
414 patients suffering from migraine with or without aura were randomized to frovatriptan 2.5 mg or rizatriptan 10 mg ( study 1 ) , frovatriptan 2.5 mg or zolmitriptan 2.5 mg ( study 2 ) , frovatriptan 2.5 mg or almotriptan 12.5 mg ( study 3 ) . - pubmed
After treating 1 - 3 episodes of migraine in no more than 3 months with the first treatment , patients switched to the other treatment for the next 3 months . - pubmed
In this analysis , traditional migraine endpoints were compared between the 66 men and 280 women of the intent - to - treat population . - pubmed
This may imply that patients affected by a neurodegenerative disease may benefit from treatment with selective inhibitors of innate immune activity . - pubmed
TDF nephrotoxicity has been reported in both HIV - infected and noninfected patients . - pubmed
Study design , follow - up , size of study population , treatment group , patient demographics , number of patients exposed to TDF or non - TDF control , baseline characteristics , investigator - defined criteria for renal AEs , and number of discontinuations due to a presumed renal AEs were extracted . - pubmed
Arrested development of the dorsal column following neonatal spinal cord injury in the opossum , Monodelphis domestica . - pubmed
We describe the morphological changes that occur in the dorsal column ( DC ) of the grey short - tailed opossum , Monodelphis domestica , following spinal cord injury at two early developmental ages . - pubmed
This age - differential response , together with other facets of remodelling that occur after neonatal spinal injury , might explain the locomotor adaptations and recovery observed in these animals . - pubmed
METHODS : Studies were conducted among hemodialysis ( HD ) patients with ESRD due to type 2 DM nephropathy , chronic glomerulonephritis , chronic infective tubulointerstitial nephritis , and hypertensive nephropathy as well as in healthy subjects . - pubmed
RESULTS : No significant differences in a frequency distribution of tested polymorphisms were shown between type 2 DM nephropathy patients and controls . - pubmed
Different traits for FHB resistance in wheat were identified for common wheat ( Triticum aestivum L. ) while the sources of FHB resistance in durum wheat ( Triticum turgidum ssp . - pubmed
The objective of our research is to identify potential cell wall biochemical traits linked to Fusariosis resistance to be transferred from a resistant common wheat to a susceptible durum wheat line . - pubmed
These include early involvement in the patient 's care by a wound prevention specialist and the incorporation of a cholera cot design into the spinal transport board with a hole to completely offload the sacral tissue and permit the drainage of stool . - pubmed
OBJECTIVE : The aim of our study was to investigate the ductus venosus doppler between 11 - 13 + 6 ( week - day ) in pregnant women with hemoglobinopaties and its relation with fetal outcomes . - pubmed
MATERIAL AND METHODS : A total of 100 pregnant women with hemoglobinopathies and 100 healthy pregnant women were included in our study . - pubmed
This study examines the interactions between Arabidopsis thaliana ( Arabidopsis ) and the pathogenic oomycete Hyaloperonospora arabidopsidis ( Hpa ) by enhancer trapping to uncover novel plant genes involved in local infection responses . - pubmed
Biologically synthesised silver nanoparticles from three diverse family of plant extracts and their anticancer activity against epidermoid A431 carcinoma . - pubmed
METHODS : In this multicenter randomized controlled trial , cancer patients ( aged 8 - 18 years ) and their parents filled in questionnaires on HrQoL , depressive symptoms , behavioral problems , and self - esteem . - pubmed
RESULTS : SSAs have shown to help the symptomatic and biochemical improvement of patients with NETs and to exhibit a good safety profile . - pubmed
MATERIALS AND METHODS : A retrospective cohort study was carried out on 619 patients with papillary thyroid carcinoma between 2006 and 2012 ; we analyzed the sociodemographic , histological , prognostic and clinical characteristics . - pubmed
This phase 3 , double - blind , placebo - controlled , randomised - withdrawal study evaluated the long - term maintenance of GXR efficacy in children / adolescents with ADHD . - pubmed
METHODS : Children / adolescents ( 6 - 17 years ) with ADHD received open - label GXR ( 1 - 7 mg / day ) . - pubmed
CONCLUSIONS : Guanfacine hydrochloride demonstrated long - term maintenance of efficacy compared with placebo in children / adolescents with ADHD . - pubmed
diskImageR was used to examine the response of the human fungal pathogen Candida albicans to the antifungal drug fluconazole across different strain backgrounds and growth conditions . - pubmed
A 73 - year - old man was admitted with stuporous mentality and left hemiparesis after a motor - vehicle accident . - pubmed
The patient was treated conservatively at the intensive care unit in the acute stage to prevent extent of stroke . - pubmed
The Effects of Ultraviolet Eye Irradiation on Dextran Sodium Sulfate - Induced Ulcerative Colitis in Mice . - pubmed
This study evaluated change in gait , performance - based function , and self - reported function 1 year after TKA in patients with symptomatic knee osteoarthritis and how these aspects interrelate . - pubmed
METHODS : A total of 28 patients ( 64 % female ) with knee osteoarthritis , with a mean age of 66 ( + -7 ) years , and 25 age- and gender - matched controls participated in this prospective cohort study . - pubmed
RESULTS : Kinetic gait deviations of both the operated and non - operated limb persisted in patients with knee osteoarthritis at 1 year after surgery , while kinematic gait patterns were comparable to controls . - pubmed
Performance on the 5STS and KOOS scores in patients with knee osteoarthritis improved significantly 1 year after surgery ( effect size 0.5 - 1.5 ) , but did not reach the level of controls . - pubmed
Ten patients with knee osteoarthritis ( 36 % ) exceeded the minimally detectable change on the 5STS . - pubmed
METHODS : A total of 35 patients with CKD and 25 healthy controls , were enrolled and we have evaluated inflammatory indexes , mineral metabolism , renal function , renal and cardiovascular ultrasonographic parameters . - pubmed
RESULTS : Tricuspid anular plane systolic excursion ( TAPSE ) and estimated pulmonary artery systolic pressure ( ePAPs ) showed a statistically significant difference between CKD patients and healthy controls ( p<0.001 , p=0.05 ) . - pubmed
Accurate assessment of right ventricular function is recommended in patients with CKD . - pubmed
RRI and echocardiographic parameters can be an important instrument for the diagnosis , prognosis and therapeutic assessment of cardio - renal syndrome in these patients . - pubmed
Ophthalmologic Outcomes of Children Born Premature Without ROP : Correlations With Gestational Age and Psychomotor Development . - pubmed
PURPOSE : To study ophthalmological outcomes of premature children with no retinopathy of prematurity ( ROP ) and correlate with neurodevelopmental outcomes . - pubmed
Children with any motor disability tended to have worse vision . - pubmed
The study includes 300 CAD patients , 100 FDRS , and 300 controls . - pubmed
METHODS : We searched PubMed , EMBASE , and Cochrane search trials databases in English to identify studies comparing data on disease recurrence in PTC patients with mETE and those with no ETE . - pubmed
The recurrence rate in patients with mETE is significantly higher when compared with those with no ETE ( risk ratio = 1.70 , 95 % confidence interval : 1.26 - 2.28 , I = 56 % ) . - pubmed
CONCLUSION : mETE is a risk factor for poor prognosis in patients with PTC . - pubmed
The frequency of hyperparathyroidism was higher in the children with 25 - OHD levels<18.0 ng / mL than in the children with 25 - OHD levels>=18.0 ng / mL ( P<0.0001 ) . - pubmed
Hypocalcemia was more prevalent in the children with 25 - OHD levels<18.0 ng / mL than in the children with 25 - OHD levels>=18.0 ng / mL ( P<0.0001 ) . - pubmed
Surgical resection of metastases represents an integral part of curative management in patients with testicular germ cell tumors ( GCT ) . - pubmed
In clinical stage IIA / B , nsRPLND is indicated for patients with marker - negative metastases in whom cure rates of about 65 % can be achieved with surgery alone . - pubmed
For NSGCT , pRTR is indicated in patients with residual masses & gt;1 cm and negative or plateauing tumor markers to resect persisting teratoma or vital cancer . - pubmed
METHODS : We conducted an Asian multinational phase II study for patients with gastric GISTs & gt;=10 cm . - pubmed
Embracing early discharge in patients with lower gastrointestinal bleeding . - pubmed
Using human prostate tumor cell line PC-3 as a model , an obvious induction of cell proliferation could be detected with a cell viability of 53.3 % , which was stronger than single cargo delivery , indicating the synergistic effect between these two components . - pubmed
Prevalence of Mycoplasma genitalium and other sexually transmitted infections causing urethritis among high - risk heterosexual male patients in Estonia . - pubmed
BACKGROUND : We aimed to evaluate the prevalence of sexually transmitted infections ( STI , including Mycoplasma genitalium , Chlamydia trachomatis , Neisseria gonorrhoeae , Trichomonas vaginalis ) among high - risk heterosexual male patients and to clarify their potency to cause complaints and inflammation . - pubmed
gonorrhoeae has the highest potency to generate urethral inflammation followed by C. - pubmed
Profiling microRNA from Brain by Microarray in a Transgenic Mouse Model of Alzheimer ' s Disease . - pubmed
Microarray analysis revealed 56 differentially expressed miRNAs in AD mouse brain , which involved 39 miRNAs that were significantly upregulated and 19 that were downregulated at different ages . - pubmed
Among those miRNAs , a total of 11 miRNAs , including miR-342 - 3p , miR-342 - 5p , miR-376c-3p , and miR-301b-3p , were not only conserved in human but also predicted to have targets and signaling pathways closely related to the pathology of AD . - pubmed
INTRODUCTION : Optimal management of malignant pleural effusion ( MPE ) is important in the care of patients with advanced cancer . - pubmed
VATS - pleurectomy offered no survival advantage in a RCT of mesothelioma patients . - pubmed
It is essential to understand the pathophysiology of cardiogenic shock and the possible deterioration of contractile function during high - risk PCI in order to select those patients who could benefit from mechanical support thus choosing the most suitable device in every situation . - pubmed
Aldehyde would irreversibly damage bacterial cell wall and cytoplasmic membrane , resulting in decay and death of bacterial cells . - pubmed
The study included 63 patients with SSc in age from 16 to 67 years ( mean 42 years ) , among whom there were 11 % men and 89 % women . - pubmed
As the control parameters studied in 52 healthy people and 42 patients with limited scleroderma . - pubmed
SSc is accompanied by violations of BRP , which is manifested by increasing viscoelasticity module parameters in 8 % of patients , and the surface tension in 66 % on the background of reducing surface elasticity level in 37 % , and the latters two parameters of interfacial tensiometry differ not only from those in healthy people as well as in patients with limited scleroderma , and changes in the viscoelastic properties of the blood are prevalent in diffuse form of the disease compared to the limited form when there are dispersive correlation BRP with the severity of skin lesions and extradermal manifestations of SSc ( heart , lung , kidney disease ) , and the elastic and relaxation serum characteristics have predictive value , respectively , in the cases of limited and diffuse forms of the disease . - pubmed
METHOD : The study included 120 patients hospitalized at a major level I regional trauma center for the care of ( 1 ) closed long bone or calcaneus fractures and/or ( 2 ) an intraabdominal injury caused by blunt force trauma and requiring surgical repair ( i.e. - pubmed
Interestingly , the abundance of Akkermansia , a bacterial genus associated with loss of body weight , was elevated dramatically in mice subjected to a diet composed exclusively of meat . - pubmed
This pathogen causes vascular wilt symptoms and death in both E. - pubmed
The seven isolates could be differentiated from a strain isolated from a diseased E. - pubmed
The purpose of this study was to determine the function of female sexual hormones on the gastric damage induced by I / R in male rats . - pubmed
Methods : Forty ( 40 ) Wistar rats were randomized into five groups : intact , ischemia- reperfusion ( IR ) , IR + estradiol ( 1mg / kg ) , IR + progesterone ( 16 mg / kg ) and IR + combination of estradiol ( 1 mg / kg ) and progesterone ( 16 mg/ kg ) . - pubmed
Association between blood pressure variability and the short - term outcome in patients with acute spontaneous subarachnoid hemorrhage . - pubmed
The association between the fluctuation in blood pressure ( BP ) and the early outcomes of patients with subarachnoid hemorrhage ( SAH ) remains unclear . - pubmed
Our study aimed to evaluate the value of blood pressure variability ( BPV ) for predicting the short - term outcomes of patients with acute spontaneous SAH . - pubmed
We collected data from 303 patients hospitalized for acute spontaneous SAH . - pubmed
In conclusion , systolic BPV within the first 24 h after admission was independently associated with the outcomes in SAH patients ; the greater the variability was , the worse the outcome . - pubmed
The importance of estrogen for bone protection in experimental hyperthyroidism in human osteoblasts . - pubmed
INTRODUCTION : Magnetic resonance imaging ( MRI ) is increasingly used in patients with rheumatoid arthritis ( RA ) to determine residual inflammation after treatment and as a predictor of structural damage progression . - pubmed
Early neurological complications in children with classical galactosemia and p.gln188arg mutation . - pubmed
BACKGROUND : Despite implementation of a controlled diet , children with classical galactosemia ( CG ) may develop a variety of developmental and cognitive problems . - pubmed
In this study , we examined the early developmental status of , as well as the neurological and neuroradiological findings for , children with CG . - pubmed
METHODS : We retrospectively evaluated 46 galactosemia patients who were followed between 2003 and 2017 . - pubmed
There were 21 women and 21 men 21 - 70 years of age ( Avg 49 ) with operatively treated tibial plateau fractures . - pubmed
Across groups , patients with bicondylar fractures tended to have higher VAS than those with unicondylar fractures and to use more narcotics although neither was statistically significant . - pubmed
INTERVENTION APPROACH : The integrated HIV care services model consisted of 5 care coordination components : 1 ) case management , 2 ) HIV health care ( primary health care ) , 3 ) behavioral health care ( mental and substance abuse screening and treatment ) , 4 ) adherence counseling ( a pharmacist - led intervention ) , and 5 ) social support services ( transportation , emergency food assistance , housing , and legal assistance ) . - pubmed
Rats in the experimental group were injected with lipopolysaccharide ( LPS ) through the tail vein to prepare the model of sepsis - induced kidney injury , while those in the control group with the equal volume of normal saline . - pubmed
Of 1304 consecutively admitted patients with type 2 diabetes , we enrolled 410 patients satisfying the criteria in this study . - pubmed
OBJECTIVE : The aim of this systematic review was to evaluate the effect of therapies for cognitive impairment on patients ' perceived cognitive function in breast cancer survivors with chemotherapy - related cognitive impairment . - pubmed
Aborted myocardial infarction in patients with STEMI treated with mechanical reperfusion . - pubmed
BACKGROUND : Aborted myocardial infarction ( abMI ) is a type of acute coronary syndrome in which patients treated with reperfusion avoid the large burden of necrosis . - pubmed
METHODS : This is a retrospective registry of 1693 consecutive patients with STEMI treated with pPCI . - pubmed
CONCLUSION : Patients with abMI have better short and long term outcomes . - pubmed
Feasibility Case Study for Treating a Patient with Sensory Ataxia Following a Stroke with Kinesthetic Illusion Induced by Visual Stimulation . - pubmed
We examined the effects of KINVIS intervention in a patient with sensory ataxia . - pubmed
CASE : The patient was a 59 - year - old man with a severe proprioceptive deficit caused by left thalamic hemorrhage . - pubmed
Complement C5 inhibition in patients with COVID-19 - a promising target ? - pubmed
Sex differences in patients with cardiogenic shock requiring extracorporeal membrane oxygenation . - pubmed
OBJECTIVE : Our study assesses differences between male and female patients placed on venoarterial extracorporeal membrane oxygenation for cardiogenic shock . - pubmed
METHOD : We retrospectively analyzed 574 adult patients placed on venoarterial extracorporeal membrane oxygenation for cardiogenic shock at our institution between January 2007 and December 2018 . - pubmed
In contrast to the situation in sub - Saharan Africa where hepatitis B virus is incriminated as the most important etiologic factor of HCC , it was found in the present study that alcoholism was a very essential cause of cirrhosis and thereby of HCC . - pubmed
Adult cattle in a Queensland dairy herd with a history of deaths from lymphosarcoma were sampled regularly over a 4 year period for the identification of animals with persistent lymphocytosis ( PL ) . - pubmed
Two of these animals had lymphocytosis and two lymphoblastic leukaemia . - pubmed
The calf of one of the latter cows developed lymphoblastic leukaemia and lymphosarcoma by the time it was 6 months of age . - pubmed
Although histological evidence of lymphosarcoma was lacking in a number of clinically normal animals with lymphocytosis , haematological investigation identified a group of animals within the herd that may develop lymphosarcoma . - pubmed
In an experimental system , newborn rats were totally protected against viral leukemogenesis by prenatal immunization of mothers with either live or inactivated leukemia virus . - pubmed
Although all had a satisfactory PaO2 ( mean , 49 mm Hg ) postoperatively , the PGE1 - nonresponsive patient experienced serious intraoperative bradycardia , hypotension , and acidosis in contrast to the PGE1 - responsive group . - pubmed
All had signs of acute hepatitis at delivery , and hepatitis B surface antigenemia persisted two to four weeks after delivery . - pubmed
It is concluded that the salvage of patients with para - aortic metastasis will be small , but for those few long - term survivors , the benefit will be great . - pubmed
Postoperative complications and survival after pancreatoduodenectomy in patients aged over 70 years . - pubmed
An analysis of postoperative complications and survival was conducted in 31 patients undergoing pancreatoduodenectomy ( PD ) for carcinoma of the pancreas or periampullary carcinoma . - pubmed
Definite pancreatic leakage was found in one patient in the over 70 group , and one case each of pancreatic , biliary , and gastric leakage were found in the under 70 group . - pubmed
The cumulative survival rate of the patients aged over 70 years with carcinoma of the pancreas or periampullary carcinoma did not differ significantly from the rate of those under 70 . - pubmed
It was thus concluded that PD achieves an adequate prognosis and survival in patients over 70 years of age . - pubmed
An analysis of the results of 9 patients with a post - traumatic malalignment of the tibia , treated by an osteotomy and immediate bone grafting through a posterolateral approach is presented . - pubmed
Viruses ( rhinovirus , parainfluenza virus , and influenza virus ) and fungi ( Aspergillus , zygomycoses , Phaeohyphomycis , Pseudallescheria , and Hyalohyphomycis ) have also been reported to cause ACAS . - pubmed
50 de novo patients with Parkinson ' s disease were investigated in a retrospective study after selegiline ( -)deprenyl monotherapy and a combination of ( -)deprenyl and levodopa . - pubmed
During the treatment period the distribution of age ( below 60 yr or above 60 yr ) among the Hoehn - Yahr stages was similar to that of the baseline period , while the clinical disability for the patients starting with hypokinesis meant a more severe state compared to the cases with tremor . - pubmed
Of 14 alcoholics , 7 had alcoholic hepatitis alone , while the other 7 had cirrhosis plus alcoholic hepatitis . - pubmed
Of 16 non - alcoholic patients with chronic viral infection , 6 had chronic active hepatitis and 10 cirrhosis plus chronic active hepatitis . - pubmed
[ Ventricular arrhythmia and late potentials in patients with hypertrophic cardiomyopathy ] . - pubmed
A prevalence of spontaneous ventricular arrhythmias could be determined in 51 patients ; the results of 45 patients not taking antiarrhythmic drugs are presented here . - pubmed
Absolute counts of premature beats were low in most patients , but important interindividual differences could be observed : M = 34 extrasystoles/24 h ( 0 - 4943 ) . - pubmed
All patients were asymptomatic during tachycardia . - pubmed
The influence of the maintenance medium , polyethylene glycol ( PEG ) , DEAE - dextran , and low temperature on reproduction of influenza A , B , and C viruses and their reassortants in diploid and continuous cell cultures was determined . - pubmed
Treatment of cells with PEG solution increased the yield of influenza B and C but not A viruses . - pubmed
However , influenza A virus strains proved to be capable of producing infectious progeny in nonpermissive cell lines treated with PEG . - pubmed
Pentavalent technetium-99 m ( V )- DMSA uptake in a pheochromocytoma in a patient with Sipple ' s syndrome . - pubmed
This case report describes 99mTc ( V )- dimercaptosuccinic acid ( DMSA ) accumulation in a pheochromocytoma in a patient with Sipple ' s syndrome . - pubmed
Phenotypic patterns of preneoplastic and neoplastic hepatic lesions in woodchucks infected with woodchuck hepatitis virus . - pubmed
Chronic infection of woodchucks with woodchuck hepatitis virus ( WHV ) was associated with the development of hepatitis , foci of altered hepatocytes and hepatocellular adenomas and carcinomas . - pubmed
The phenotypic similarities and the close spatial relationship between the foci of altered hepatocytes , and the hepatocellular adenomas and carcinomas in WHV - infected woodchucks , suggest that these lesions are preneoplastic . - pubmed
Hyperglycemia produces a variety of effects , including osmotic diuresis and cognitive dysfunction , which seriously impair the quality of life of the older individual . - pubmed
Fourteen patients with benign symptomatic non - parasitic cysts of the liver were either surgically treated , had alcohol injected into the cysts , underwent deroofing of the cyst or in 5 , a cystectomy was done . - pubmed
Alcohol was injected into 6 patients and there has been no recurrence for as long as 5 years and 8 months after the treatment . - pubmed
Liver dysfunction occurred in 3 patients given blood transfusion during the surgery and/or postoperative course , an elevated temperature ( over 39 degrees C ) occurred in one patient . - pubmed
Note on an association of Clostridium novyi type A and Clostridium sordellii with a case of gas - gangrene in a Zebu cow . - pubmed
A case of gas - gangrene myositis on a Zebu cow with association of Clostridium novyi type A and Clostridium sordellii is described . - pubmed
[ Use of crystepin in combination with obsidan in patients with diabetes mellitus with arterial hypertension ] . - pubmed
Examination included 70 patients with diabetes mellitus in combination with arterial hypertension of different origin ( II stage essential hypertension and symptomatic renal arterial hypertension ) . - pubmed
The hemodynamic hypotensive effects in these patients due to the influence of the above therapy are uniform and depend on the form of attendant arterial hypertension . - pubmed
The hypotensive effect of crystepin used in combination with obsidan was more pronounced in patients with diabetes and II stage essential hypertension than that in those with diabetes and renal hypertension . - pubmed
We used the sheep lung lymph fistula - endotoxin model of ARDS to test this hypothesis . - pubmed
Urinary glycosaminoglycans , sialic acid and lysosomal enzymes increase in nonalbuminuric diabetic patients . - pubmed
We prospectively followed 39 adults with concurrent primary herpes simplex virus ( HSV ) infection ( 12 with HSV type 1 and 27 with HSV type 2 ) of the oropharynx and genitalia , caused by the same virus in each person , to evaluate the influence of viral type ( HSV-1 vs. HSV-2 ) and site of infection ( oropharyngeal vs. genital ) on the frequency of recurrence . - pubmed
Oral - labial recurrences developed in 5 of 12 patients with HSV-1 and 1 of 27 patients with HSV-2 ( P less than 0.001 ) . - pubmed
Conversely , genital recurrences developed in 24 of 27 patients with HSV-2 and 3 of 12 patients with HSV-1 ( P less than 0.01 ) . - pubmed
The mean rate of subsequent genital recurrences ( due to HSV-1 and HSV-2 ) was 0.23 per month , whereas the mean rate of oral - labial recurrences was only 0.04 per month ( P less than 0.001 ) . - pubmed
We conclude that the likelihood of reactivation of HSV infection differs between HSV-1 and HSV-2 infections and between the sacral and trigeminal anatomical sites . - pubmed
The majority of patients with recurrent corneal erosion respond to conventional forms of therapy such as topical lubricants , patching , debridement , or bandage soft contact lenses . - pubmed
Of 21 eyes in 18 patients treated in this manner , three eyes required retreatment of adjacent areas ; otherwise , there were no recurrences in follow - up periods ranging from 5 months to 12 years . - pubmed
Presence of Rous sarcoma virus inside the mitochondria isolated by zonal and differential centrifugation from Rous sarcoma cells . - pubmed
The survival of surgically and medically treated patients with left main - stem coronary artery stenosis has been analysed in detail . - pubmed
From 1978 to 1981 , 85 patients with stenosis of the left main coronary artery greater than 50 % were divided into two groups ; 47 were treated surgically and 38 medically . - pubmed
The opiate quasiwithdrawal syndrome in rhesus monkeys : comparison of naloxone - precipitated withdrawal to effects of cholinergic agents . - pubmed
Serum renotropic activity and renal growth in spontaneously hypertensive rats . - pubmed
[ Monitoring of plasma theophylline levels in asthmatic patients treated with oxtriphylline ] . - pubmed
In intact unanesthetized rats , microinjection of a local anesthetic in the pontine tegmentum resulted in thermoregulatory responses , such as curling of the body , piloerection , tremor in facial muscles , and shivering . - pubmed
The influence of three categories of anti - cancer agents on competence development and on the binding of homologous DNA to cells have been studied in the Bacillus subtilis transformation system . - pubmed
In 7 patients with end - to - side portacaval shunts it was 94 + /- 18 % , in 3 patients with distal splenorenal shunts 57 + /- 11 % , and in 10 patients with cirrhosis of the liver it varied between 15 % and 85 % . - pubmed
The embryotoxic potential of ochratoxin A and citrinin was studied after administering , either subgerminally or intraamniotically , single mounting doses of the mycotoxins to chicken embryos on days 2 , 3 , and 4 . - pubmed
It may be supposed that citrinin produced together with ochratoxin A in some strains of Penicillium viridicatum Westling does not potentiate the clear - cut embryotoxic action of the latter mycotoxin . - pubmed
Pyridoxal-5 '- phosphate determination by a sensitive micromethod in human blood , urine and tissues ; its relation to cystathioninuria in neuroblastoma and biliary atresia . - pubmed
Nifedipine treatment for pulmonary hypertension in a patient with systemic sclerosis . - pubmed
Vulnerability of the hippocampus to kainate excitotoxicity in the aged , mature and young adult rat . - pubmed
Sensitivity to excitotoxic damage was assessed in young adult , mature and aged male Sprague - Dawley rats . - pubmed
A new antimycotic drug lamisil ( Sandoz , Switzerland ) was given as pills to 35 patients with pedal mycosis ( 23 of them suffered from onychomycosis ) . - pubmed
For 30 years we have followed the case of a euthyroid patient who had a goiter diagnosed at age 15 . - pubmed
In a euthyroid patient , the association of an elevated serum PBI concentration ( with an abnormally large butanol - insoluble iodine fraction ) with a diffuse goiter that became nodular and calcified may be unique . - pubmed
Renovascular disease in patients with hypertension : detection with systolic and diastolic gating in three - dimensional , phase - contrast MR angiography . - pubmed
Islet autotransplantation can prevent surgically induced diabetes after total pancreatectomy in adults ; however , the efficacy of this procedure has not been established in children . - pubmed
The authors report the case of a 12 - year - old boy who underwent total pancreatectomy and islet autotransplantation for intractable pain caused by idiopathic chronic pancreatitis . - pubmed
Postoperatively , the patient had complete relief of abdominal pain . - pubmed
Human cytomegalovirus ( CMV ) can persist in many organs after primary infection . - pubmed
Not only is it suspected to cause morbidity during reactivation in patients under immunosuppression , but it may also induce long - term latency by chronic disease , e.g. - pubmed
CMV - DNA could be assessed in 5 - 14 % of patients in the different stages of myocarditis and in 22 % of patients with DCM . - pubmed
Although two biopsies of the control group showed a positive result , studies by in - situ hybridization demonstrated that in patients with heart muscle disease CMV persists in all cell types including myocytes , whereas in the controls it is only found in interstitial cells . - pubmed
In a previous study , 30 pregnant women suffering from headaches were treated with physical therapy , relaxation training , and biofeedback . - pubmed
The results indicate that the reductions in headache activity were maintained at follow - up in the majority of the women treated , with 67.5 % of the sample maintaining a significant decrease in headache up to 1 year after giving birth . - pubmed
Non - epileptic attack disorders in children and adolescents : a single case study . - pubmed
[ Prognostic factors and results of treating 42 patients with nln - seminomatous germ cell tumor of the testis ] . - pubmed
In 1984 - 1988 , 42 patients with non - seminomatous germ - cell tumour of the testis were treated surgically in combination with chemotherapy . - pubmed
The authors report an unusual case of bilateral short term acute orchitis in a patient with recurrent polyserositis ( familial Mediterranean fever ) . - pubmed
METHODS AND MATERIALS : Twenty - one patients with histologically confirmed locally advanced inoperable NSCLC ( Stage IIIA or IIIB ) were entered on study . - pubmed
Because of severe myelosuppression in the first two patients , etoposide only was subsequently changed to 20 mg / m2 i.v . - pubmed
Five patients ( 25 % ) developed severe radiation pneumonitis , leading to early closure of the study . - pubmed
CONCLUSIONS : Combining daily protracted cisplatin and etoposide with concurrent thoracic irradiation in patients with locally advanced unresectable NSCLC yields a high overall response rate and a median survival that is at least comparable to other combined modality trials . - pubmed
Pathophysiology of Trypanosoma congolense infection in two breeds of sheep , Scottish blackface and Finn Dorset . - pubmed
The pathophysiology of Trypanosoma congolense infection was studied in two breeds of sheep , the Scottish Blackface ( SB ) and Finn Dorset ( FD ) , which were known from previous studies to differ significantly in their susceptibility to haemonchosis , in which anaemia is also the primary pathophysiological effect . - pubmed
Wilms ' tumor gene expression in human CD34 + hematopoietic progenitors during fetal development and early clonogenic growth . - pubmed
PROCEDURE : Body weight was recorded , and blood samples were collected from dogs before , during , and after a 300 - mile race . - pubmed
Body weight and estimated total exchangeable cation content in dogs also decreased significantly during the race . - pubmed
Rats were made chronically epileptic by a period of continuous electrical stimulation of the hippocampus , which establishes an acute condition of self - sustained limbic status epilepticus ( SSLSE ) . - pubmed
This period of SSLSE is followed by a development of chronic recurrent spontaneous limbic seizures that are associated with chronic neuropathological changes reminiscent of those encountered in human TLE . - pubmed
Great apes ( Pongidae ) possess a chromosome similar to human chromosome 21 ( HSA21 ) , whose trisomy was described in both chimpanzee and orangutan . - pubmed
This exposed the human and Pongidae ancestry to trisomy 21 for a period of 30 - 50 million years , while , in other catarrhines , the equivalent of HSA21 was further involved in various translocations forming large chromosomes whose aneuploidy , very probably incompatible with life , protected them against trisomy 21 . - pubmed
To study differentiation capacities of HCDCs , cells were attached to hydroxyapatite / tricalcium phosphate ceramic and transplanted subcutaneously into immunodeficient mice . - pubmed
A 78 - year - old woman was admitted to our hospital on September 14 , 1992 , because of systemic myalgia and stiffness , joint pain , and gait disturbance . - pubmed
Recently , some patients with polymyalgia rheumatica have been reported to have anti - cardiolipin antibody in serum . - pubmed
MATERIAL AND METHODS : From January 1982 to December 1995 , all patients with a daily alcohol intake in the previous year of at least 50 g per day and all patients with alcoholic cirrhosis whatever their drinking habits were studied . - pubmed
Two thousand one hundred eight patients had liver biopsy ; 37 % had histologically proven or probable cirrhosis . - pubmed
Forty one percent of the patients without cirrhosis who had liver biopsy already had steatofibrosis and/or acute alcoholic hepatitis . - pubmed
DESIGN , SETTING , PARTICIPANTS : The performance measure , which assesses adherence to antipsychotic dose recommendations for acute schizophrenia treatment , was calculated at hospital discharge for 116 patients with schizophrenia who had participated in a 6 - month outcomes study . - pubmed
Alarm pheromone enhances stress - induced hyperthermia in rats . - pubmed
Experimentally naive male Wistar rats were exposed to the test chambers containing alarm pheromones , which had been released by other rats receiving foot shocks in the same chamber beforehand . - pubmed
Antioxidant micronutrients found in fruits and vegetables have been shown in numerous studies to be protective against cancer . - pubmed
Cryptococcus neoformans ( Cn ) is a soil fungus that causes life - threatening meningitis in immunocompromised patients and is a facultative intracellular pathogen capable of replication inside macrophages . - pubmed
Microscopy , fungal and amoebae killing assays , and phagocytosis assays revealed that Cn is phagocytosed by and replicates in Acanthamoeba castellanii , which leads to death of amoebae . - pubmed
BACKGROUND : Percutaneous administration of dihydrotestosterone ( DHT ) has been successful in promoting phallic growth in infants and children with 5 alpha - reductase deficiency raised as males . - pubmed
We investigated whether percutaneous administration of DHT is similarly effective in patients with micropenis due to alternative diagnoses . - pubmed
METHODS : Six patients ( age range 1.9 - 8.3 years ) with micropenis of variable etiology were studied prospectively . - pubmed
CONCLUSION : Percutaneous administration of DHT in a dose of 0.2 - 0.3 mg / kg once daily for a period of 3 - 4 months may be useful in the management of patients with testosterone biosynthetic defects , who have sufficient masculinization to warrant male sex assignment , or in patients with micropenis prior to reconstructive surgery . - pubmed
Do antioxidants ( vitamins C , E ) improve outcomes in patients with coronary artery disease ? - pubmed
Fluid extravasation during cardiopulmonary bypass in piglets -- effects of hypothermia and different cooling protocols . - pubmed
Twenty patients were randomly assigned to intra - operative end tidal PCO2 of 3.99 ( control ) or 5.99 kPa ( hypercapnia ) . - pubmed
Mean ( SD ) subcutaneous tissue oxygen tension was 8.39 ( 1.86 ) kPa in control and 11.84 ( 2.53 ) kPa hypercapnia patients ( p = 0.014 ) . - pubmed
Increases in subcutaneous tissue oxygen partial pressure similar to those observed in patients assigned to hypercapnia are associated with substantial reductions in wound infection risk . - pubmed
METHODS AND MATERIALS : We report 10 - year biochemical relapse - free survival ( BRFS ) on 232 patients presenting with localized prostate cancer and consecutively treated with iodine(125 ) ( I(125 ) ) or palladium(103 ) ( Pd ( 103 ) ) brachytherapy and neoadjuvant external beam radiation therapy . - pubmed
Selective immunohistochemical staining shows significant prognostic influence of lymphatic and blood vessels in patients with malignant melanoma . - pubmed
Few data on the influence of lymphatic microvessel density ( LMVD ) on survival in patients with melanoma are available . - pubmed
into mice , angiogenesis and tumor growth were inhibited . - pubmed
The combination of mitoxantrone - steroids improves clinical symptoms , namely by reducing pain , but does not improve patient survival . - pubmed
Average Hg concentrations in small rainbow trout from all lakes , including Pinchi L. , were lower than dietary levels reported to cause reproductive impairment in common loons ( Gavia immer ) ; however , Hg levels in small pikeminnow from Pinchi L. were sufficiently high to be of concern . - pubmed
The risk for Hg toxicity in the study area is greatest for animals that consume larger piscivorous fish such as larger northern pikeminnow or lake trout , which are known from previous studies to contain higher Hg concentrations . - pubmed
Hepatopulmonary syndrome in a patient with primary biliary cirrhosis . - pubmed
A 54 - year - old Japanese woman with primary biliary cirrhosis ( PBC ) was admitted to our hospital due to hepatic coma and refractory pleural effusion . - pubmed
Five RAPD - types with similar ITS sequences and phenotype were related to the ex - type strain of Penicillium pallidum ( generally given as a synonym of G. - pubmed
MATERIALS AND METHODS : Sublethally irradiated C57Bl / 6 mice were intravenously transplanted with rigorously purified lymphoid and myeloid progenitors from a congenic mouse strain . - pubmed
The patient was an 81 - year - old woman with 2 separate thymomas in the anterior mediastinum . - pubmed
In Brazil , envenomation evoked by snakes , spiders and scorpions are an important public health problem . - pubmed
One patient underwent an extracapsular cataract extraction after the device was implanted , as a senile cataract was then noted . - pubmed
Neonatal herpes simplex virus ( HSV ) can be a devastating illness and may be difficult to diagnose in those cases without a typical skin rash . - pubmed
As a result , physicians often rely on HSV polymerase chain reaction of cerebrospinal fluid to rule out HSV encephalitis . - pubmed
PURPOSE : To investigate the potential role of commercially available topical fluoroquinolones in diffuse lamellar keratitis ( DLK ) using New Zealand White rabbit models . - pubmed
The fungus , Histoplasma capsulatum , produces a persistent infection . - pubmed
In such situations , bacteremia and infectious complications may be caused by translocation of either gastrointestinal bacteria or its toxins as the result of bacterial overgrowth , loss of intestinal epithelial integrity , or immunologic compromising of the host . - pubmed
RECENT FINDINGS : Recent studies have shown that probiotics play a role in decreasing postoperative complications in patients undergoing major gastrointestinal operations . - pubmed
[ Separation and purification of phosphatidylcholine in swine liver and its inhibition effect on proliferation of rat hepatoma cells ] . - pubmed
The effect of the PC with different concentrations on the proliferation of rat hepatoma cell line ( CBRH-7919 ) was determined by microculture tetrazolium ( MTT ) assays in vitro and was compared with that of human leukemia cell line K562 . - pubmed
It suggested that PC derived from animal liver might function as a specific inhibitor for hepatoma cells in a concentration dependent manner . - pubmed
Cd - tolerant bacterial strains of fluorescent pseudomonads , mostly belonging to Pseudomonas monteillii , were isolated from termite mound soil ( Macrotermes subhyalinus , a litter - forager and fungus - growing termite ) , in a Sudanese shrubby savanna , Burkina Faso . - pubmed
UNLABELLED : In a 5 - year study involving 119 postmenopausal women , zoledronic acid 4 mg given once - yearly for 2 , 3 or 5 years was well tolerated with no evidence of excessive bone turnover reduction or any safety signals . - pubmed
The present study investigated the presence and prognostic role of tumour necrosis ( TN ) and reactive perivascular T - cell infiltrate ( RPVI ) , defined as a rim of small reactive T - lymphocytes occurring alone or located between the vascular wall and large neoplastic cells , in tumour samples from 100 immunocompetent patients with PCNSL . - pubmed
World Health Organization histotypes of the patients were : 96 diffuse large B - cell lymphomas , two Burkitt - like lymphomas , one anaplastic large T - cell lymphoma and one unclassified B - cell lymphoma . - pubmed
Patients with RPVI - positive lesions exhibited a significantly better overall survival ( OS ) than patients with RPVI - negative lymphoma , particularly among patients treated with high - dose methotrexate - based chemotherapy ( 3 - year OS : 59 + /- 14 % vs. 42 + /- 9 % , P = 0.02 ) . - pubmed
To prevent the chronic carriage of HBV in Saudi children , hepatitis B vaccine was added as the seventh immunogen in the expanded program on immunization ( EPI ) . - pubmed
METHODS : We evaluated the frequency and type of neurological complications in patients initially presenting with ophthalmic herpes zoster at an ophthalmological department in a Danish university hospital , over a 7 - year period . - pubmed
RESULTS : Of the 110 immunocompetent patients who presented with initial ophthalmic zoster , six ( 5.5 % ) suffered from neurological complications other than post - herpetic neuralgia . - pubmed
Four experienced isolated cranial motor nerve palsies , one patient had meningitis with a favourable outcome and one patient had severe encephalitis with a poor clinical outcome . - pubmed
The protecting effects and mechanisms of Baicalin and Octreotide on heart injury in rats with SAP . - pubmed
PURPOSE : To observe the protecting effects and mechanisms of Baicalin and Octreotide on heart injury in rats with severe acute pancreatitis ( SAP ) . - pubmed
CONCLUSION : Baicalin and Octreotide have protecting effects on heart injury of rats with SAP . - pubmed
Additionally , CAs and cytotoxicity induced by cyfluthrin were investigated in rat ( Rattus norvegicus var . - pubmed
The frequency of chromosome aberrations in bone - marrow cells of rats treated with the test substance increased significantly ( P<0.05 ) for all doses ( 250 , 500 and 1000 mg / kg body weight ) for the two treatment periods ( 12 and 24 h ) and the two administration routes , viz . - pubmed
OBJECTIVE : To explore the effect of the pillar implant system in the management of snoring and OSAHS patients . - pubmed
METHOD : All patients are divided into three groups by PSG : mild to moderate OSAHS , severe OSAHS and snoring . - pubmed
AHI was reduced from 17.03 + /- 10.63 preoperatively to 11.17 + /- 9.52 postoperatively in 28 patients with mild to moderate OSAHS and the total effective ratio was 67.9 % . - pubmed
AHI was reduced from 62.93 + /- 9.21 preoperatively to 55.42 + /- 13.77 postoperatively in 6 patients with severe OSAHS and the effective ratio was 16.7 % . - pubmed
CONCLUSION : The pillar implant system had a significant effect on mild to moderate OSAHS patients . - pubmed
PATIENT(S ): A 35 - year - old woman with no previous history of surgery had endometriosis in the canal of Nuck excised incompletely via an open skin method . - pubmed
The recovery of the brain from anoxia after application of analeptic drugs ; electroencephalographic studies on rabbits . - pubmed
Discriminating virulence mechanisms among Bacillus anthracis strains by using a murine subcutaneous infection model . - pubmed
In the murine model of pulmonary infection , B. - pubmed
infections using two different genetically complete ( pXO1(+ ) pXO2(+ ) ) strains of B. - pubmed
These experiments demonstrate that the dominant virulence factors used to establish infection by B. - pubmed
METHODS : Twenty three patients with CTO , stable angina and a positive exercise test result were included in the study . - pubmed
Patients who remained persistently depressed at 4 months had their clinical case notes reviewed to determine whether their low mood had been recognized or treated . - pubmed
Depressed patients had higher disease activity scores ( DAS28 ) at all time points , and patients with persistent depression had smaller reductions in DAS28 [ median ( interquartile range or IQR ) change DAS28 1.71 ( 0 - 2.6 ) vs 2.2 ( 1.5 - 3.2 ) ; P = 0.005 ] . - pubmed
Only 57 % ( 13/23 ) patients with persistent depression at 4 months had their depression recognized or managed within the rheumatology clinic . - pubmed
The opiate antagonist , naltrexone , has been used successfully in the treatment of SIB in individuals with autism or mental retardation . - pubmed
Consistent with these results in the rat , a review of the clinical use of naltrexone in SIB is also suggestive of a relative loss of efficacy at higher doses ( apparent therapeutic window ) . - pubmed
Besides a gene in the tetraploid wheat variety ' Altar ' that is identical to the hexaploid wheat Lr10 , two additional , functional resistance alleles showing sequence diversity were identified by virus - induced gene silencing in tetraploid wheat lines . - pubmed
OBJECTIVES : To report the case of a 37 year - old woman suffering from endometriosis of the urinary tract , that presented with lumbar and pelvic pain associated to cyclic recurrent haematuria . - pubmed
CONCLUSIONS : The frequency of endometriosis in the urinary tract is relatively low and therefore , endometriosis presenting with ureteral obstruction ( uretero - hydronephrosis ) has been rarely reported in the literature and should be part of the differential diagnosis in young women , especially if symptoms are cyclic . - pubmed
Intraventricular infusion of hyperosmolar dextran induces hydrocephalus : a novel animal model of hydrocephalus . - pubmed
None of the animals with hydrocephalus had obstruction of the aqueduct or other parts of CSF pathways on MRI . - pubmed
Apoptosis and cell proliferation correlated with tumor grade in patients with ampullary carcinoma . - pubmed
OBJECTIVE : To evaluate apoptosis and cell proliferation on cytologic specimens ( smears ) from endoscopic retrograde cholangiopancreatography in patients with ampulary carcinoma and to correlate that relationship with the grade of the tumors . - pubmed
STUDY DESIGN : Forty patients ( 23 males and 17 females ) aged 45 - 81 who underwent endoscopic retrograde cholangiopancreatography were diagnosed by cytology as having ampullary adenocarcinoma and the diagnoses were confirmed histologically after an operation . - pubmed
CONCLUSION : Apoptosis ( cell death ) and cell proliferation increase as the grade of the differentiation decreases in ampullary carcinoma , suggesting a rapid turnover of the tumor cells with lower grates of differentiation , and apoptosis may play an important role in the growth of the tumors in patients with ampullary carcinomas . - pubmed
Recent evidence suggests that illness due to toxoplasmosis in immunocompetent persons may be related to infection with an atypical genotype ; these strains are mouse virulent . - pubmed
The isolate ( designated TgBbUS1 ) was mouse virulent ; mice inoculated with 1 oocyst or 1 tachyzoite died of acute toxoplasmosis . - pubmed
Issues of importance in these smaller trials include choice of agent , selection of appropriate trial participants , trial design , method of access to breast tissue in women without cancer , selection and monitoring of SEBs , and monitoring of drug toxicity . - pubmed
The various medicinal properties attributed to Scutellaria baicalensis include anti - bacterial , anti - viral , anti - inflammatory and anti - cancer effects . - pubmed
Sex differentiation is influenced by a combination of hormonal , social and environmental factors and teleost fishes exhibit many examples of hermaphroditism . - pubmed
This atypical clinical presentation of STEC O104 : H4 infection might indicate new severe complications associated with this uncommon strain , and highlights the importance of immediate interdisciplinary assessment of STEC / VTEC patients . - pubmed
PATIENTS AND METHODS : Nineteen children among whom 11 boys and 8 girls aged on average 5.3 - years old presented 7 recent and 12 late hip dislocations . - pubmed
An arthrotomy was performed in children with a recent dislocation . - pubmed
Purinergic signaling inhibits human acute myeloblastic leukemia cell proliferation , migration , and engraftment in immunodeficient mice . - pubmed
In the present study , we show that ATP and UTP have strikingly opposite effects on human acute myeloblastic leukemia ( AML ) cells . - pubmed
Recently , Ohnishi and Razzaque suggest that phosphate toxicity accelerates the mammalian aging process and that reducing the phosphate burden can delay the aging ( FASEB J 24 , 3562 , 2010 ) . - pubmed
Fifty - nine patients with 71 fractures met criteria for study inclusion . - pubmed
OBJECTIVE : The natural history of patients with metabolic syndrome ( MetS ) undergoing hemodialysis access placement is unknown . - pubmed
RESULTS : Of the 187 patients who underwent hemodialysis access placement , 115 ( 61 % ) were identified to have MetS. - pubmed
A 33 - year - old man with chest pain , left upper lobe mass , pulmonary nodules , and bilateral bullae . - pubmed
Elastography , spleen size , and platelet count identify portal hypertension in patients with compensated cirrhosis . - pubmed
BACKGROUND & amp ; AIMS : Noninvasive methods are needed to identify clinically significant portal hypertension ( CSPH ) and esophageal varices ( EVs ) in patients with compensated cirrhosis . - pubmed
We looked for markers of the presence of CSPH and EVs in patients with cirrhosis . - pubmed
METHODS : We performed a cross - sectional study that included a training set of 117 patients with compensated cirrhosis , confirmed by histology , from a tertiary referral center . - pubmed
We assessed the ability of platelet count , spleen diameter , LS , and combinations of these factors ( ie , ratio of platelet count to spleen size , and LS x spleen size / platelet count [ LSPS ] ) to identify patients with CSPH and EV . - pubmed
RESULTS : LS was the best single noninvasive variable for identifying patients with CSPH ( area under the receiver operating characteristic , 0.883 ; 95 % confidence interval [ CI ] , 0.824 - 0.943 ; P & lt ; .0001 ) . - pubmed
Analyses of the varices risk score and LSPS were superior to all other noninvasive tests for identifying patients with EVs ( area under the receiver operating characteristic , 0.909 ; 95 % CI , 0.841 - 0.954 and 0.882 ; 95 % CI , 0.810 - 0.935 , respectively ) ; they correctly classified 85 % of patients in the training set and 75 % in the validation set . - pubmed
Interspecies comparative analyses of gene expression profiles also showed that marginal B - cell lymphoma and diffuse large B - cell lymphoma in dogs and humans might represent a continuum of disease with similar drivers . - pubmed
Finally , we developed a benchtop diagnostic test based on expression of 4 genes that can robustly classify canine lymphomas into one of these 3 subgroups , enabling a direct clinical application for our results . - pubmed
BACKGROUND : Erlotinib is registered for treatment of all patients with advanced non - small - cell lung cancer ( NSCLC ) . - pubmed
Subjects in group A were exposed to 5.0 mg / kg body weight of caffeine dissolved in 200 mL of water on their first visit , whereas those in group B were exposed to 200 mL of water . - pubmed
Chemical burn caused by topical application of garlic under occlusion . - pubmed
Allium sativum ( garlic ) can cause an irritant contact dermatitis , secondary to naturopathic practices . - pubmed
We report an unusually severe case of chemical burn following garlic applied under occlusion . - pubmed
Echocardiographic assessment of left atrial volume index in elderly patients with anterior wall myocardial infarction . - pubmed
Enlarged left atrium ( LA ) predicts outcomes in patients with heart failure , atrial fibrillation and stroke . - pubmed
Therefore we studied left atrial volume index ( LAVi ) in elderly patients with left ventricle anterior infarction and correlated LAVi with left ventricle ejection fraction ( LVEF ) and transmitral Doppler flow . - pubmed
Relationship between ischemia / reperfusion injury and acute rejection of allogeneic liver transplant in rats . - pubmed
OBJECTIVE : This study aimed to investigate the relationship between the severity of ischemia / reperfusion ( I / R ) injury and the acute rejection ( AR ) of allogeneic liver transplants in rats . - pubmed
The rats were humanely killed at 1 , 3 , 5 , and 7 days after transplantation or sham operation to determine the severity of I / R injury , rejection classification , and hepatocyte apoptosis . - pubmed
Further study and clinical trials are needed to confirm the benefits of systemic treatment in gastric cancer patients with liver metastasis . - pubmed
Further , this activity will be evaluated both in vivo and in vitro in response to infection with Mycobacterium smegmatis to get an insight if there exists a co relation between the Mycobacterium tuberculosis infection and khat chewing . - pubmed
Feasibility and effectiveness of posaconazole prophylaxis in combination with micafungin bridging for patients undergoing allogeneic stem cell transplantation : a 6 - yr analysis from the cologne cohort for neutropenic patients . - pubmed
Patients receiving POS - MIC were less likely to develop a pneumonic infiltrate ( RR 0.71 , 95 % CI 0.51 - 1.00 ) or possible IFD ( RR 0.36 , 95 % 0.15 - 0.87 ) . - pubmed
One of the most common complications of childhood obesity is the non - alcoholic fatty liver disease ( NAFLD ) , which is the most common form of liver disease in children . - pubmed
The relatively small modifications in gene expression associated with chimerism is compatible with the high level of cooperation observed among different strains of D. - pubmed
Postpartum osteoporosis and vertebral fractures in two patients treated with enoxaparin during pregnancy . - pubmed
Here , we report severe PPO and multiple vertebral compression fractures in two patients treated with enoxaparin -- low - molecular - weight heparin ( LMWH)--throughout their pregnancy . - pubmed
A 34 - year - old woman who has delivered her second baby 3 months ago presented with severe low - back pain . - pubmed
The other patient was a 36 - year - old woman diagnosed with PPO and vertebral fractures at the third week postpartum . - pubmed
These findings suggest that vertebral compression fractures and PPO may be one of the causes of severe back pain in postpartum patients . - pubmed
METHODS : Administrative databases , in four cross sections ( annually from 2007 to 2011 ) were consulted to analyse 149,015 individual records from patients aged & gt;= 35 years with type 2 diabetes mellitus . - pubmed
The observation that approximately 15 % of women with disseminated breast cancer will develop symptomatic brain metastases combined with treatment guidelines discouraging single - agent chemotherapeutic strategies facilitates the desire for novel strategies aimed at outright brain metastasis prevention . - pubmed
Here , we develop a novel method to quantitate early metastatic events ( arresting and extravasation ) in addition to traditional end time - point parameters such as tumor burden and survival in an experimental mouse model of brain metastases of breast cancer . - pubmed
METHOD : Thirty - seven OCD patients and 33 healthy comparison subjects learned to avoid shocks while undergoing a functional MRI scan . - pubmed
RESULTS : Excessive habit formation in OCD patients , which was associated with hyperactivation in the caudate , was observed . - pubmed
CONCLUSIONS : OCD patients exhibited excessive habits that were associated with hyperactivation in a key region implicated in the pathophysiology of OCD , the caudate nucleus . - pubmed
DCs isolated from mice that had received resting but not activated ACs could transfer the suppression of inflammation to recipient mice . - pubmed
Ten children with HPA with known mutations were recruited for validating the method . - pubmed
Clinical outcomes , including adverse events , in 52 advanced breast cancer patients treated with eribulin chemotherapy after taxane treatment ( TX ) were analyzed to confirm the effectiveness and safety of this treatment . - pubmed
On the other hand , the number of patients with sensory peripheral neuropathy of Grade 1 or more was significantly more in the TX group than in the non - TX group . - pubmed
In addition , sensory peripheral neuropathy is a possible complication that can occur in advanced breast cancer patients treated with eribulin chemotherapy with taxane treatment history . - pubmed
BACKGROUND : Hexaploid triticale could be either synthesized by crossing tetraploid wheat with rye , or developed by crossing hexaploid wheat with a hexaploid triticale or an octoploid triticale . - pubmed
CONCLUSION : This study confirms that whole D - genome chromosomes could be preferentially eliminated in the hybrid of common wheat x rye , " genome shock " was accompanying the allopolyploidization of nascent triticales , and great morphologic divergence might result from the genetic variations . - pubmed
Thus , the change of confluent white matter lesions may be used as a surrogate marker in proof - of - concept trials with small patient numbers needed to show treatment effects on lesion progression . - pubmed
CASE PRESENTATION : We present a 29 year - old woman with a rapid course of hereditary diffuse leukodystrophy with spheroids . - pubmed
The nude mice model of endometriosis was constructed and the endometrial cell nodule formation was observed . - pubmed
MATERIAL AND METHODS : One hundred and fifty - four patients ( age range : 28 - 69 ) with severe chronic asthma ( study group ) and 141 patients with chronic mild disease ( control group ) diagnosed according to GINA criteria were included in the study . - pubmed
An earlier onset of asthma together with a greater number of exacerbations was noted in severe asthmatics compared to patients with mild disease . - pubmed
More IDA patients had complications after surgery ( 40.4 % vs. 27.7 % ; P less than 0.001 ) , such as nonabsorption ( 22.4 % vs. 16.5 % ; P less than 0.001 ) ; digestive ( 15.6 % vs. 10.2 % ; P less than 0.001 ) ; and gastrojejunal ulcer ( 7.6 % vs. 2.0 % ; P less than 0.001 ) . - pubmed
Male and female mice from reciprocal consomic strains originating from the C57BL/6ByJ and 129P3 / J strains were bred and measured for body weight , length , and adiposity . - pubmed
Mechanistic studies in mice and humans have implicated formation of a reactive metabolite , mitochondrial dysfunction and oxidant stress as critical events in the pathophysiology of APAP - induced liver cell death . - pubmed
It was recently suggested that ATP released from necrotic cells can directly cause cell death in mouse hepatocytes and in a hepatoma cell line ( HepG2 ) . - pubmed
Furthermore , addition of ATP did not cause mitochondrial dysfunction or enhance APAP - induced mitochondrial dysfunction in primary murine hepatocytes , although ATP did cause cell death in murine RAW macrophages . - pubmed
CONCLUSIONS : It is unlikely that ATP released from necrotic cells can significantly affect cell death in human or mouse liver during APAP hepatotoxicity . - pubmed
RELEVANCE FOR PATIENTS : Understanding the mechanisms of APAP - induced cell injury is critical for identifying novel therapeutic targets to prevent liver injury and acute liver failure in APAP overdose patients . - pubmed
METHODS : BALB / c mice were randomly assigned to five groups , and ALF was induced in mice by intraperitoneal injection of D - GaIN ( 600 mg / kg ) and LPS ( 10 mug / kg ) . - pubmed
neoaurum JC-12 / pMTac - ksdd was 5.94 g / L , increased about 22.2 % compared to the original strain M. - pubmed
Correlation of Stomatitis and Cutaneous Toxicity With Clinical Outcome in Patients With Metastatic Renal - Cell Carcinoma Treated With Everolimus . - pubmed
PATIENTS AND METHODS : We retrospectively reviewed the clinical data of patients with mRCC treated with everolimus in 2 Italian centers . - pubmed
RESULTS : Seventy - nine mRCC patients treated with everolimus ( 57 male , 22 female ; median age 66 years ; range , 44 - 88 years ) were evaluated . - pubmed
Effect of Descemet Membrane Endothelial Keratoplasty on Color Vision in Patients With Fuchs Dystrophy . - pubmed
PURPOSE : To assess changes in color discernment after Descemet membrane endothelial keratoplasty ( DMEK ) in patients with Fuchs endothelial corneal dystrophy ( FECD ) . - pubmed
METHODS : In this prospective , single - center study , the study group was composed of 26 patients with FECD , aged 46 to 85 years , who underwent DMEK as a single surgical procedure ; 24 ( 92 % ) had pseudophakic and 2 ( 8 % ) had phakic eyes . - pubmed
A control group of 14 subjects , aged 57 to 85 years , was tested 1 month after cataract surgery . - pubmed
CONCLUSIONS : Consistent with spontaneous comments from some patients with FECD that colors appear more vivid after DMEK , a comparison of pre- and postoperative color vision scores showed that color discernment usually improved after DMEK ( 81 % ) . - pubmed
[ Acoustic analysis in patients with unilateral arytenoid dislocation and unilateral vocal fold paralysis ] . - pubmed
OBJECTIVE : To analysis the acoustic characteristics in patients with unilateral arytenoid dislocation and unilateral vocal fold paralysis , and evaluate the application value of acoustic analysis technique in these two diseases . - pubmed
METHOD : The voice signals of sustained vowel /a/ were measured using the software MDVP in 50 healthy adults and 67 patients with unilateral vocal cord movement disorders . - pubmed
All patients were divided into arytenoid dislocation group ( 36 cases ) and vocal fold paralysis group ( 31 cases ) through the laryngeal electromyography . - pubmed
CONCLUSION : The acoustic parameters are effective parameters to measure the voice quality of patients with unilateral arytenoid dislocation and unilateral vocal fold paralysis . - pubmed
Experiments on isolated perfused rat heart modeled 45 - min global ischemia followed by 30 - min reperfusion . - pubmed
RESULTS : The screening performance was assessed for the 156,122 children studied , of which 151,258 belonged to the group of not - at - risk children ; and 4864 to the group at risk of hypoacusia . - pubmed
METHODS : This technique was used in 6 patients with heavily calcified craniopharyngiomas ( 2 recurrent ) who had presented with progressive visual loss . - pubmed
All of the patients had transient diabetes insipidus . - pubmed
Two patients who had preoperative hypopituitarism required long - term postoperative hormonal replacement . - pubmed
Viral proliferation and expression of tumor - related gene in different chicken embryo fibroblasts infected with different tumorigenic phenotypes of avian leukosis virus subgroup J. - pubmed
Subgroup J avian leukosis virus ( ALV - J ) causes a neoplastic disease in infected chickens . - pubmed
The ALV - J strain NX0101 , which was isolated from broiler breeders in 2001 , mainly induced formation of myeloid cell tumors . - pubmed
To identify the molecular pathological mechanism underlying changes in host susceptibility and tumor classification induced by these two types of ALV - J strains , chicken embryo fibroblasts derived from chickens with different genetic backgrounds ( broiler breeders and laying hens ) and an immortalized chicken embryo fibroblasts ( DF-1 ) were prepared and infected with strain NX0101 or HN10PY01 , respectively . - pubmed
We therefore examined whether in the murine model of tuberculosis , the anti - inflammatory effects of 1,25 ( OH ) 2D3 would affect the outcome of M. tuberculosis infection . - pubmed
tuberculosis infected mice led to a change in lung granuloma architecture , characterized by a marked decrease in B cell lymphocytic aggregates . - pubmed
Consistent with the altered granulomas , 1,25 ( OH ) 2D3 - treated mice also exhibited significantly higher bacterial burden in the lungs compared to the control group . - pubmed
OSA patients scored significantly lower on 7 domains of SF-36 compared to the population . - pubmed
PATIENTS : Nonintubated patients without mechanical ventilation ( n = 90 ) presenting with sepsis - induced acute circulatory failure and considered for volume expansion . - pubmed
After volume expansion , a relevant ( & gt;= 10 % ) stroke volume index increase was recorded in 56 % patients . - pubmed
CONCLUSIONS : The collapsibility index of the inferior vena cava during a deep standardized inspiration is a simple , noninvasive bedside predictor of fluid responsiveness in nonintubated patients with sepsis - related acute circulatory failure . - pubmed
Intravenous methylprednisolone had a poor response and the patient was submitted to ulnar nerve decompression , which confirmed nerve abscess with purulent discharge during surgery . - pubmed
As the patient weighed more than 40 kg , treatment with a pediatric dose was considered insufficient and adult - dose MDT was prescribed , with improvement of nerve pain and function . - pubmed
There is scant literature about the imaging findings of nerve abscess in leprosy patients . - pubmed
Radiologists should suspect leprosy in patients with no other known causes of neuropathy when detecting asymmetric nerve enlargement and nerve abscess on ultrasound . - pubmed
Outcomes of first line chemotherapy in patients with chronic lymphocytic leukemia . - pubmed
Aim of this study was to determine the outcomes of patients with chronic lymphocytic leukemia treated with different available chemotherapeutic regimens . - pubmed
METHODS : All patients with diagnosis of CLL from 2008 to 2013 were included . - pubmed
OBJECTIVE : To assess the efficacy of active treatment targeted at underlying disease ( TTD)/potentially curative treatments versus palliative care ( PC ) in improving overall survival ( OS ) in terminally ill patients . - pubmed
Despite recent advances in curing chronic hepatitis C ( CHC ) , the high economic burden to therapy , viral drug resistance , difficult to treat hepatitis C virus ( HCV ) genotypes and patient groups are still of concern . - pubmed
IDPP was synergistic in combination with FDA - approved HCV drugs and inhibited pre - existing resistant HCV strains induced by today 's therapies . - pubmed
Systematic Review of Safety and Cost - Effectiveness of Venous Thromboembolism Prophylaxis Strategies in Patients Undergoing Craniotomy for Brain Tumor . - pubmed
BACKGROUND : Studies have evaluated various strategies to prevent venous thromboembolism ( VTE ) in neuro - oncology patients , without consensus . - pubmed
METHODS : A literature search was conducted for VTE prophylaxis in brain tumor patients . - pubmed
CONCLUSION : Although MP+LMWH is frequently considered the optimal prophylaxis for VTE risk reduction , our model suggests that MP+UFH is the safest and most cost - effective measure to balance VTE and hemorrhage risks in brain tumor patients at lower risk of hemorrhage . - pubmed
MP+LMWH may be more effective for patients at higher risk of VTE . - pubmed
Late pubertal growth spurt in a girl with growth hormone deficiency : Is Kaufmann therapy effective in a girl with short stature who responds poorly to growth hormone therapy and estrogen - replacement therapy ? - pubmed
A Japanese senior high school girl aged 18 years and 5 months with growth hormone deficiency was referred for primary amenorrhea . - pubmed
Failure of the vascular hypothesis of multiple sclerosis in a rat model of chronic cerebrospinal venous insufficiency . - pubmed
The present study was designed to validate this hypothesis using a rat model of CCSVI . - pubmed
The rats were followed clinically for eight months and neurological examination detected no weakness or paralysis in the operated rats . - pubmed
Transmission from human to human is one of its main characteristics in comparison with other fungi responsible for invasive infections . - pubmed
PCP is caused by genotypically distinct mixtures of organisms in more than 90 % of cases , reinforcing the hypothesis that there is constant inhalation of P. - pubmed
MATERIAL AND METHODS We enrolled 240 patients with BPPV from Beijing Chaoyang Hospital between July 2013 and July 2016 . - pubmed
Although the level of SUA was lower in BPPV patients , SUA was not an independent risk factor for BPPV . - pubmed
MATERIALS AND METHODS : We retrospectively identified 122 patients who presented to the emergency department from April 2011 through April 2016 with recent direct trauma to the anterior segment of the eye . - pubmed
This critically important sign predicted anterior globe rupture in 39 of 47 patients ( odds ratio , 68.25 ; p & lt ; 0.0001 ) . - pubmed
BACKGROUND : Patients with amnestic mild cognitive impairment ( aMCI ) have an increased risk of dementia . - pubmed
Therefore , predicting the dementia conversion in these patients is important . - pubmed
OBJECTIVE : We aimed to develop a nomogram to predict dementia conversion in aMCI subjects using neuropsychological profiles . - pubmed
METHODS : A total of 338 aMCI patients from two hospital - based cohorts were used in analysis . - pubmed
All patients were classified into 1 ) verbal , visual , or both , 2 ) early or late , and 3 ) single or multiple - domain aMCI according to the modality , severity of memory dysfunction , and multiplicity of involved cognitive domains , respectively . - pubmed
Patients were followed up , and conversion to dementia within 3 years was defined as the primary outcome . - pubmed
Here , we review the factors that might contribute to the low vaccine efficacy , including passive transfer of maternal rotavirus antibodies , rotavirus seasonality , oral polio vaccine ( OPV ) administered concurrently , microbiome composition and concomitant enteric pathogens , malnutrition , environmental enteropathy , HIV , and histo blood group antigens . - pubmed
Feasibility of Concurrent Chemoradiation in Patients treated for Esophageal Carcinoma : A Single Institutional Experience . - pubmed
Due to compromised nutritional status , radiation therapy in esophageal cancer patients itself is a challenge and addition of concurrent chemotherapy leads to severe side effects even when standard dose regimens are used . - pubmed
The tolerance of chemoradiation for carcinoma esophagus in Indian patients is still unclear . - pubmed
This study is an effort to know feasibility of chemoradiation in patients treated for esophageal carcinoma in our hospital . - pubmed
Feasibility of Concurrent Chemoradiation in Patients treated for Esophageal Carcinoma : A Single Institutional Experience . - pubmed
Hepatitis E virus ( HEV ) is considered the main etiological agent that causes acute hepatitis . - pubmed
Posttraumatic Stress in Children After Injury : The Role of Acute Pain and Opioid Medication Use . - pubmed
OBJECTIVES : After injury , many children experience posttraumatic stress symptoms ( PTSS ) that negatively impact recovery . - pubmed
BACKGROUND : Recently transapical off - pump mitral valve repair with NeoChord implantation has been demonstrated to be safe and effective in patients with degenerative mitral regurgitation ( DMR ) . - pubmed
METHODS : We retrospectively analyzed baseline and early postoperative 3 - dimensional transesophageal echocardiography of 66 patients who underwent NeoChord repair for isolated posterior leaflet MV disease using semiautomatic off - line analysis software . - pubmed
CONCLUSIONS : Transapical NeoChord repair produces important acute intraoperative changes in MV anatomy in DMR patients . - pubmed
Cardiac Stress and Inflammatory Markers as Predictors of Heart Failure in Patients With Type 2 Diabetes : The ADVANCE Trial . - pubmed
Two genetically different porcine epidemic diarrhea virus ( PEDV ) strains have been identified in the USA : US prototype ( also called non - S INDEL ) and S INDEL PEDVs . - pubmed
Complete genome sequence analyses indicated this PEDV variant was genetically similar to US non - S INDEL strain but had a continuous 600 - nt ( 200 - aa ) deletion in the N - terminal domain of the spike gene compared to non - S INDEL PEDVs . - pubmed
METHODS : We retrospectively reviewed the charts of patients who experienced subaxial cervical facet injury within the Penn Health System between 1 June 2006 and 1 June 2016 to identify patients with bilateral jumped / perched facets . - pubmed
The objective of this study was to examine microvascular function in women at high risk for preeclampsia at mid - gestation . - pubmed
Patients were recruited if they met eligibility criteria indicating high risk for preeclampsia . - pubmed
Serratia marcescens is an opportunistic human pathogen causing various nosocomial infections , most importantly urinary tract infections ( UTIs ) . - pubmed
Assessing taste and smell alterations in cancer patients undergoing chemotherapy according to treatment . - pubmed
RESULTS : Seventy - six percent patients reported taste disorders and 45 % smell changes . - pubmed
Recent lines of evidence suggest that dehydroepiandrosterone ( DHEA ) , a 19 - carbon steroid hormone classified as an adrenal androgen , exerts a chondroprotective effect in OA patients , and it has been proven to be an effective DMOAD candidate that slows OA progression . - pubmed
Encouragingly , the current data on DHEA are promising and may prove that DHEA - based treatment is efficacious for preventing and slowing human OA progression . - pubmed
People with dementia had 52 % lower odds of receiving OAC compared to people without dementia . - pubmed
People with dementia had higher bleeding risk and poorer anticoagulation control when treated with warfarin . - pubmed
Allergen - specific sublingual immunotherapy is dose and duration dependent in a murine allergic rhinitis model . - pubmed
Results : The incidence rates of atelectasis two hours after extubation on the first day of surgery were 22 ( 36.7 % ) , 20 ( 33.3 % ) and 10 ( 16.7 % ) patients in the control , PEEP8 and PEEP10 groups , respectively . - pubmed
The incidence rates of atelectasis on the third day after surgery were 39 ( 65 % ) , 36 ( 60 % ) and 21 ( 35 % ) patients in the control , PEEP8 and PEEP10 groups , respectively . - pubmed
RESULTS : Among 10 604 T2DM patients included in this study , there were 3744 cases of diabetic nephropathy(35.31 % ) . - pubmed
The purpose of this study was to present the surgical outcome in optic disc pit associated maculopathy in a patient who was treated with vitrectomy , internal limiting membrane ( ILM ) peeling , barrage laser photocoagulation , and silicone oil tamponade . - pubmed
vitrectomy combined with posterior hyaloid and ILM peeling followed by silicone oil tamponade , with additional laser photocoagulation , was successful for the treatment of optic disc pit maculopathy in our patient . - pubmed
INTRODUCTION : To investigate the structural changes of the brain that correlate with physical frailty and cognitive impairments in Parkinson ' s disease ( PD ) patients . - pubmed
METHODS : Sixty - one PD patients and 59 age- and sex - matched healthy controls were enrolled . - pubmed
Exploratory group - wise comparisons of gray matter volume ( GMV ) in the PD patients and controls were conducted . - pubmed
Voxel - wise multiple linear regression analyses were conducted for physical frailty - related and cognitive impairment - related GMV changes in the PD patients . - pubmed
RESULTS : The PD patients exhibited diffuse GMV reductions in comparison to the controls . - pubmed
INTRODUCTION : There are limited data on outcomes of living donor liver transplantation ( LDLT ) for patients with severe alcoholic hepatitis . - pubmed
The patients with alcoholic hepatitis were abstinent for a duration of 4 + - 1.8 months at the time of LDLT . - pubmed
When patients with alcoholic hepatitis ( n = 39 ) were compared to patients who underwent LDLT for alcoholic liver disease without alcoholic hepatitis ( n = 461 ) , patients with alcoholic hepatitis were significantly younger ( 43.2 + - 8.5 vs. 48.2 + - 9.1 years , p = 0.001 ) and had higher Child 's ( 10.9 + - 1.5 vs. 9.8 + - 1.8 ) and MELD scores ( 22.1 + - 4.5 vs. 18.4 + - 5.9 , p = 0.000 ) . - pubmed
CONCLUSION : Living donor liver transplantation can be successfully performed with good survival for patients with severe alcoholic hepatitis . - pubmed
The relative benefits in patients with and without established atherosclerotic cardiovascular disease for different outcomes with these classes of drugs remain undefined . - pubmed
For both drug classes , this treatment effect was restricted to a 14 % reduction in those with established atherosclerotic cardiovascular disease ( HR , 0.86 ; 95 % CI , 0.80 - 0.93 ; P=0.002 ) , whereas no effect was seen in patients without established atherosclerotic cardiovascular disease ( HR , 1.01 ; 95 % CI , 0.87 - 1.19 ; P=0.81 ; P interaction , 0.028 ) . - pubmed
Their distinct clinical benefit profiles should be considered in the decision - making process when treating patients with type 2 diabetes mellitus . - pubmed
We aimed to examine the association between urinary BPA and TNs in women who are more susceptible to TNs . - pubmed
Gleno - humeral abduction measurement in patients with Ehlers - Danlos syndrome . - pubmed
METHODS AND MATERIAL : Retrospective case - control study comparing 110 patients with known EDS ( cases ) to 100 controls . - pubmed
A stratification model using regression analyses was developed to assign the patients to risk categories for wound healing and the time - to - heal . - pubmed
An ecologically important tropical freshwater microalga , Scenedesmus quadricauda , was exposed to Ni toxicity under two temperature regimes , 25 and 35 C to investigate the interactive effects of warming and different Ni concentrations ( 0.1 , 1.0 and 10.0 ppm ) . - pubmed
Evolution of platelet function in adult patients with chronic immune thrombocytopenia on romiplostim treatment . - pubmed
Eight patients with syndromic craniosynostosis underwent midface distraction osteogenesis using the type Z'gok between 2016 and 2017 ( Z'gok group ) . - pubmed
Romiplostim in patients with refractory aplastic anaemia previously treated with immunosuppressive therapy : a dose - finding and long - term treatment phase 2 trial . - pubmed
In this phase 2 trial we aimed to assess the activity and safety of romiplostim in patients with aplastic anaemia who were previously treated with immunosuppressive therapy . - pubmed
Eligible patients were aged 19 years or older , and had aplastic anaemia confirmed by bone marrow and cytogenetic studies and thrombocytopenia ( platelet count & lt;=30 x 109 / L ) , an Eastern Cooperative Oncology Group performance status score of 2 or lower , and were previously treated with immunosuppressive therapy , including at least one course of antithymocyte globulin plus cyclosporin . - pubmed
Treatment - related adverse events occurred in three ( 9 % ) of 35 patients , including grade 1 or 2 myalgia , fatigue , and dizziness . - pubmed
17 ( 49 % ) of 35 patients had adverse events of grade 3 or higher ; seven ( 20 % ) had serious adverse events ( one event of febrile neutropenia , cataract , retinal detachment , macular fibrosis , inguinal hernia , appendicitis , cellulitis , tendon injury , and transfusion reaction ) ; and one patient died from sepsis during treatment ; none of these events were related to treatment . - pubmed
INTERPRETATION : Romiplostim seems to be active and has a favourable safety profile in patients with refractory aplastic anaemia . - pubmed
We describe the case of a 42 - yr - old female patient with a 2 - yr history of headache that has progressively worsened . - pubmed
The patient presented a paresis of the oculomotor nerve that completely resolved in the 3 - mo follow - up . - pubmed
Recurrent ovarian cancer remains confined in the peritoneal cavity in > 80 % of the patients , providing an opportunity for locoregional administration of novel therapeutics , including gene and viral therapy approaches . - pubmed
In this review we cover recent advances in adenovirus - based oncolytic therapies targeting ovarian cancer and recent advances in mapping immune responses to oncolytic virus therapies in ovarian cancer . - pubmed
RESULTS : Thirteen articles reporting on 30 cases of BI during inguinal hernia repair from 1967 to 2017 were included ( 19 boys , 2 girls , 9 unknown ) . - pubmed
Analysis of a loquat tree with leaf curl symptoms by deep sequencing revealed a novel virus with a single - stranded RNA genome , for which the name " loquat virus A " ( LoVA ) was proposed . - pubmed
Delirium is prevalent in older hospital inpatients and associated with adverse outcomes : results of a prospective multi - centre study on World Delirium Awareness Day . - pubmed
Fifty - nine patients were divided into two groups : caries free ( A group ) and caries active ( B group ) . - pubmed
Expression and short - term prognostic value of miR-126 and miR-182 in patients with acute stroke . - pubmed
Expression and short - term prognostic value of miR-126 and miR-182 in patients with acute stroke were investigated . - pubmed
In total , 153 patients with acute stroke admitted to the Second Affiliated Hospital of Soochow University from February 2016 to February 2018 were enrolled into the observation group as group A [ 88 patients with acute cerebral infarction ( AIS ) ] or group B [ 65 patients with cerebral hemorrhage ( ICH ) ] . - pubmed
The receiver operating characteristic ( ROC ) curve was employed to explore the value of miR-126 and miR-182 , alone or in combination , in predicting the prognosis of acute stroke patients . - pubmed
The expression levels of miR-126 and miR-182 are associated with the neurological function , self - care ability , and prognosis in patients with acute stroke is highly valuable for predicting the prognosis of patients . - pubmed
Drawing the parallelism between vitelline layer of echinoderm eggs and the zona pellucida of mammalian eggs , we also discuss the importance of the egg surface in mediating monospermic fertilization . - pubmed
The novel severe acute respiratory syndrome - coronavirus-2 pandemic has spread to Africa , where nearly all countries have reported laboratory - confirmed cases of novel coronavirus disease ( COVID-19 ) . - pubmed
Taken together , the combined properties of the co - gels , including their stability and capacity to control both cell recruitment and cell phenotype within the murine wound bed , strongly supports the potential of the co - gel scaffolds for improved treatment of chronic non - healing wounds . - pubmed
Focused Clinical Question : In patients with endosseous dental implants that demonstrate peri - implantitis , does surgical bone augmentation with adjunctive laser implant surface disinfection have an effect on implant survival rates , and do these rates differ based on laser treatment modality ? - pubmed
Aggressive angiomyxoma to 57 - year old man . - pubmed
Severe acute respiratory syndrome coronavirus 2 ( SARS - CoV-2 ) has placed unprecedented pressure on healthcare systems , even in advanced economies . - pubmed
A 43 - year - old woman presented with impaired vision and redness in her left eye of 2 weeks duration . - pubmed
Based on the recent cat scratch and the ocular findings , cat scratch disease ( CSD ) was suspected . - pubmed
Natural substances with antioxidant effects may benefit prevention and treatment of people with or prone to bone diseases after menopause , such as osteoporosis . - pubmed
RESULTS : A total of 588 patients with severe sepsis / septic shock were enrolled . - pubmed
Based on the Sepsis-1 definition , there were 159 non - septic shock patients and 429 septic shock patients . - pubmed
Compared with the non - septic shock patients , lactate ( Lac ) level , sequential organ failure assessment ( SOFA ) score , fluid balance on the first day , and ratio of mechanical ventilation , 12 - hour acute kidney injury ( AKI ) , renal replacement therapy ( RRT ) , and postoperative ICU transition in the septic shock patients were significantly increased and the proportion of emergency admission to ICU was significantly decreased . - pubmed
Based on the Sepsis-3 definition , there were 383 non - septic shock patients and 205 septic shock patients ; the results of clinical data analysis between the two groups were similar to those based on Sepsis-1 . - pubmed
Based on Sepsis-1 , there was no significant difference in 90 - day mortality between non - septic shock and septic shock patients [ 23.90 % ( 38/159 ) vs. 29.37 % ( 126/429 ) , P > 0.05 ] . - pubmed
However , based on Sepsis-3 , the 90 - day mortality of patients with septic shock was significantly higher than that of patients with non - septic shock [ 37.56 % ( 77/205 ) vs. 22.72 % ( 87/383 ) , P < 0.01 ] . - pubmed
BACKGROUND : The impact of incidentally detected hepatocellular carcinoma ( iHCC ) in explanted liver on the prognosis of the patients undergoing orthotopic liver transplantation remains controversial with several studies reporting survival worse than true non - hepatocellular carcinoma ( non - HCC ) recipients . - pubmed
METHODS : The present study retrospectively analyzed the patients ' demographics , tumor characteristics , and outcomes of iHCC in adult patients undergoing LDLT for non - HCC indications at our center between August 2009 and March 2018 . - pubmed
iHCC was detected in the explanted livers in 28 patients ( 5.1 % ) out of 545 LDLTs . - pubmed
CONCLUSIONS : Incidence of iHCC in explanted livers after LDLT is low and most patients have very early - stage tumors with excellent recurrence - free survival . - pubmed
We found a high percentage ( 61 per cent ) of falsely positive results in patients with various hematological diseases without evidence of prostatic carcinoma by the colorimetric evaluation . - pubmed
One hundred sixty - one patients with advanced Hodgkin ' s disease achieved complete remission after combination chemotherapy . - pubmed
In a patient with no recent myocardial insult , uptake of technetium-99 m diphosphonate was noted in a region corresponding to massive calcification of the mitral annulus . - pubmed
Antidotes protect corn from thiocarbamate herbicide injury . - pubmed
11 patients with ischaemic heart disease ( IHD ) with single vessel disease served as controls . - pubmed
Myocardial perfusion defects in patients with X - syndrome were similar to those in patients with moderate , but haemodynamically significant , single vessel disease . - pubmed
The mice were killed at varying periods of time after hemorrhage to obtain KC from the liver , and assessed for their capacity to present antigen to a sensitized clone Th / cell line ( D10.G4.1 ) . - pubmed
Analysis of a cellular model to account for the natural history of infection by the hepatitis B virus and its role in the development of primary hepatocellular carcinoma . - pubmed
Infection with the hepatitis B virus ( HBV ) can have many different outcomes . - pubmed
We present two patients who experienced life - threatening immediate reactions and one patient who developed generalized urticaria following oral administration of trimethoprim ( TMP ) and sulfamethoxazole ( SMX ) combination . - pubmed
These results suggest that the three patients developed type I hypersensitivity reactions to TMP . - pubmed
In our patients skin prick tests with TMP were useful in TMP hypersensitivity diagnosis . - pubmed
A linear function , 70 ( + /- 7.3 ) + -0.15 ( + /- 0.056 ) x dose ( + /- SD ) , adequately described the excess numbers of rats with lung cancers over a beta - radiation dose range to the lungs of 6.8 to 250 Gy for two groups of rats with the highest doses to the lungs after a single exposure and for two groups with the highest doses after repeated exposure . - pubmed
It is not new but has only relatively recently become a parameter to be measured in patients treated for cardiovascular disease . - pubmed
Diuretic therapy had a greater negative impact on the quality of life of hypertensive patients than captopril , propranolol , or methyldopa alone . - pubmed
In a case - control study of 177 HIV - seropositive and 326 seronegative women and their newborns in Nairobi , Kenya , maternal HIV infection at term was independently associated with travel to other African countries [ odds ratio ( OR ) 4.9 , P less than 0.0001 ] , history of a blood transfusion since 1980 ( OR 3.5 , P = 0.01 ) , history of more than one sexual partner in the previous 5 years ( OR 1.8 , P = 0.02 ) and unmarried status ( OR 1.8 , P = 0.02 ) . - pubmed
Neonates of HIV - positive and HIV - negative women differed little with respect to occurrence of congenital malformations , stillbirths , in - hospital mortality , sex , APGAR score , or gestational age . - pubmed
However , the mean birth weight of singleton neonates of HIV - positive women was significantly lower than that of controls ( 3090 versus 3220 g , P = 0.005 ) , and birth weight was less than 2500 g in 9 % of cases and 3 % of controls ( OR 3.0 , P = 0.007 ) . - pubmed
Mitosis in embryonic trisomy 1 mouse eye . - pubmed
Cytotoxic effects of six angiographic contrast media on human endothelium in culture . - pubmed
Responses to ultraviolet - inactivated antigen prepared from BKV - infected fibroblasts were compared to those elicited against a mock antigen preparation and an unrelated control antigen ( tetanus toxoid , TET ) . - pubmed
We prepared 99mTechnetium ( V ) DMSA ( pentavalent form ) as an imaging agent for eighteen patients with proven nasopharyngeal carcinoma . - pubmed
The nasopharyngeal tumour showed tracer accumulation in only 5 out of the 18 patients ( 28 % ) . - pubmed
Two patients who received 150 mg of ACNU and daily 600 mg of UFT in combination with radiation therapy showed severe myelosuppression in the early stage of treatment , and the combination therapy was aborted . - pubmed
Two of four patients who received 100 mg of ACNU and daily 400 mg of UFT did not show such severe side effects and two showed transient , moderate myelosuppression and vomiting . - pubmed
Regulation of intakes of water and NaCl solutions in Fischer 344 rats : contrasts and comparisons between strains . - pubmed
We present an overview of the differences in intakes of both water and NaCl between different strains of rat , with emphasis on Fischer 344 ( F344 ) and Sprague - Dawley ( SD ) strains . - pubmed
Relative to SD , rats of the F344 strain show less spontaneous or secondary drinking both with food present and during food deprivation . - pubmed
The water intake of rats of the F344 strain is strongly inhibited when water is added to their food , but rats of the SD strain show less inhibition and consume excessive amounts of fluid . - pubmed
In studies of primary drinking , induced by treatment with various dipsogens , rats of the F344 strain consumed water in amounts that were generally comparable to those expected from rats of the SD strain , with the exception of reduced intakes in response to either polyethylene glycol - induced hypovolemia or treatment with isoproterenol . - pubmed
We also review findings that rats of the F344 strain show no spontaneous preference for dilute NaCl solutions , and show that both a strong preference and a low preference threshold are induced by chronic treatment with ramipril . - pubmed
In the conservative group , six patients underwent arthroscopy for meniscal tears , four medial and two lateral . - pubmed
Only seven patients returned to sports , all experiencing recurrent episodes of giving way , effusions , and pain . - pubmed
The two remaining patients both suffered reinjury 3 years after their surgery . - pubmed
We recommend arthroscopy and examination under anesthesia for the young patient with ACL tears . - pubmed
In vitro immunization procedures , using sera of athymic mice bearing human WOC ovarian tumors or CM III mammary tumors as immunizing antigen , induced a highly efficient formation of mABs ( 44 % of antibody - producing clones ) reacting with human ovarian and/or mammary tumor cells . - pubmed
Immunogenicity of normal mouse components in the sera from tumor bearers can be excluded since control immunization with sera of normal athymic mice yielded no mABs reacting with mouse or human cell lines . - pubmed
Focal atrial tachycardia with frequencies up to 200 / min in an 11 - year - old girl had been resistant to drugs over a period of 5 years . - pubmed
Clinical and/or biochemical evidence of hypothyroidism occurred in three patients , two of whom required treatment with L - thyroxine . - pubmed
An additional patient had persistent hyperthyroxinemia but no clinical evidence of hyperthyroidism . - pubmed
In the past 11 years we have operated on three patients with " tiny " parathyroid adenomas ( less than 60 mg ) . - pubmed
Permanent microscopic sections confirmed the diagnosis of parathyroid adenoma in all three patients . - pubmed
The culture of human foetal pancreatic tissue may be useful in maintaining responsive beta cells and may help to ensure an adequate amount of donor tissue for future transplantation into diabetic patients . - pubmed
Effect of venous hypertension on canine hind limb lymph . - pubmed
The effect of acute and chronic venous hypertension on the lymph draining from the hind limb has been studied in 10 dogs . - pubmed
The saline - insoluble particulate material obtained by pulmonary lavage from four patients with alveolar proteinosis was analyzed for total lipid ( 52 % ) , protein ( 44 % ) , and carbohydrate ( 4 % ) . - pubmed
Acute inflammation and granulation tissue formation in neutropenic rats . - pubmed
[ Effectiveness of the agents of the 2d series in treating patients with chronic destructive tuberculosis of the lungs ] . - pubmed
Congenital lipoprotein lipase deficiency and hyperlipemia in the young puppy . - pubmed
Effect of isopropamide on response to oral cimetidine in patients with Zollinger -- Ellison syndrome . - pubmed
Patients with Zollinger - Ellison syndrome whose gastric acid secretion or symptoms were not controlled by cimetidine in conventional dosage were selected for studies of responsiveness of their acid secretion to increasing doses of cimetidine , used either alone or in combination with a long - acting anticholinergic agent , isopropamide iodide . - pubmed
Basal and stimulated by means of isoproterenol lipolysis was similar in adipose tissue either in persons with normal arterial blood pressure or in patients with hypertensive disease . - pubmed
Arthritis in a 15 - year - old boy with juvenile diabetes mellitus . - pubmed
The clinical and pathological features of 20 patients with coexistent squamous cell carcinoma and adenocarcinoma of the uterine cervix have been analyzed . - pubmed
In an attempt to resolve this apparent disagreement , we exposed White Carneau pigeons to drinking water containing calcium ( 100 ppm ) , magnesium ( 30 ppm ) , lead ( 0.8 ppm ) , or cadmium ( 0.6 ppm ) and used a 2(4)-factorial design to measure the effects of these elements in atherosclerosis and hypertension . - pubmed
We suggest that , if these results with the pigeon can be applied to humans , the incidence of aortic atherosclerosis and hypertension should be significantly higher in areas where the drinking water contains magnesium , lead , and cadmium with a relatively low calcium concentration . - pubmed
In 34 patients with different chronic skin diseases ( including eczemas , lichen ruber , erythrodermia , pyodermia , pemphigus erythematosus , vasculitis , parapsoriasis varioliformis , scleroderma adultorum Buschke , prophyria cutanea tarda , rosacea , dermatomyositis , erythematodes chronicus discoides and indurative tuberculosis ) , X - ray studies revealed sacroiliac - changes consistent with a low - grade inflammation . - pubmed
We reviewed 32 children with lower extremity injuries caused by power lawn mowers . - pubmed
METHOD : Echoic memory was investigated in 20 schizophrenic subjects and 20 age- and IQ - matched normal comparison subjects with the use of nondelayed and delayed tone matching . - pubmed
RESULTS : Schizophrenic subjects were markedly impaired in their ability to match two tones after an extremely brief delay between them ( 300 msec ) but were unimpaired when there was no delay between tones . - pubmed
With respect to the neoplasms , Kaposi ' s sarcoma was observed in patients with different degrees of immunosuppression . - pubmed
AIMS : To evaluate further the relation between gastric malignant lymphoma of the mucosa associated lymphoid tissue ( MALT ) and Helicobacter pylori . - pubmed
Unilateral complete airway obstruction persisted in 8 of the 12 rabbits . - pubmed
[ Effects of zuzhongping on ischemic volume in the rat model of middle cerebral artery occlusion ] . - pubmed
Effect of epinephrine treatment during late ischemia and early reperfusion on regional myocardial function and infarct size in partially infarcted reperfused porcine hearts . - pubmed
Case report -- The first patient male , aged 23 , presented a sequestrum in the vestibular alveolar wall in correspondence with 1.1 and 1.2 . - pubmed
The patient underwent two operations ( one using a craniotomy route and the other using a trans - sphenoidal route ) to remove a giant pituitary adenoma . - pubmed
Impact of axillary lymph node dissection on the therapy of breast cancer patients . - pubmed
PURPOSE : We studied a series of 283 breast cancer patients retrospectively to determine the actual benefits of axillary lymph node dissection ( ALND ) for these patients . - pubmed
CONCLUSION : The benefits of ALND vary greatly for different groups of breast cancer patients , and controlled studies may be needed to determine whether ALND is necessary for all breast cancer patients . - pubmed
Conformational features of a synthetic cyclic peptide corresponding to the complete V3 loop of the RF HIV-1 strain in water and water / trifluoroethanol solutions . - pubmed
The disulfide - bridge - closed cyclic peptide corresponding to the whole V3 loop of the RF HIV-1 strain was examined by proton two - dimensional NMR spectroscopy in water and water / trifluoroethanol solutions . - pubmed
[ Acute intrahepatic bleeding in a male patient with focal nodular hyperplasia ] . - pubmed
HISTORY AND CLINICAL FINDINGS : A 45 - year - old man had acute bouts of pain in the right lower thorax with radiation to the mid - thorax and upper abdomen . - pubmed
Substrates were crosslinked with 0 % or 0.25 % glutaraldehyde , populated with cells , and grafted to full - thickness wounds on athymic mice ( n = 6 / condition ) . - pubmed
METHODS : Between 1982 and 1992 , 6 patients with Crohn ' s disease and leukemia underwent allogeneic marrow transplantation and were followed up clinically . - pubmed
RESULTS : Five patients had active Crohn ' s disease before transplantation , and 3 had clinical evidence of sclerosing cholangitis . - pubmed
One patient died of septicemia 97 days after transplantation ; 5 patients were observed for 4.5 , 5.8 , 8.4 , 9.9 , and 15.3 years after transplantation . - pubmed
Four of 5 patients evaluated had no signs or symptoms of Crohn ' s disease after transplantation . - pubmed
One patient with mixed donor - host hematopoietic chimerism had a relapse of Crohn ' s disease 1.5 years after transplantation . - pubmed
CONCLUSIONS : Four of 5 patients followed up for 4.5 to 15.3 years after allogeneic hematopoietic cell transplantation remained free of Crohn ' s disease . - pubmed
SUBJECTS : One hundred and seventy children , aged 8 - 36 months , were recruited at the clinical ward and public health service section of the hospital : 61 normal children , 49 moderately malnourished ( underweight ) children and 60 severely malnourished children ( 19 kwashiorkor , 30 marasmus , and 11 marasmic kwashiorkor children ) . - pubmed
MEASUREMENTS AND MAIN RESULTS : Seventy - five patients had neither signs of respiratory distress nor deterioration in gas exchange during the trial and were extubated . - pubmed
CONCLUSIONS : Three - quarters of ventilated children can be successfully weaned after a trial of spontaneous breathing lasting 2 h. Both tidal volume and frequency - to - tidal volume ratio indexed to body weight were poor predictors of weaning failure in the study population . - pubmed
A 69 - year - old man with chronic dizziness . - pubmed
We report the unrecognized accidental intratracheal insertion of a nasogastric tube , following endotracheal intubation in a patient scheduled to undergo right lower lobectomy for carcinoma . - pubmed
The 1p31 region shows loss of heterozygosity in up to 50 % of human breast cancers , indicating the presence of a tumor suppressor gene in this location . - pubmed
The aim of this study was to investigate the efficacy of MC in isolated , perfused rat hearts , and to see whether MC itself induced myocardial cell injury and functional impairment . - pubmed
Langendorff - perfused rat hearts ( n = 89 ) from several experimental series subjected to 30 min of global ischaemia and 60 min of reperfusion were retrospectively analysed . - pubmed
SUBJECTS : 2158 patients aged & gt;40 years were screened by questionnaires and case record reviews ; 357 patients with past or present signs or symptoms of heart disease were identified , of whom 126 were eligible for and consented to examination . - pubmed
RESULTS : 15 patients ( 12 % ) had left ventricular systolic dysfunction . - pubmed
Significant improvement in symptoms has been reported with the use of continuous positive airway pressure in patients with OSA . - pubmed
The aim of the present study was to describe the results of the evaluation of brain - dead patients as potential cardiac donors in a French teaching hospital that manages the largest number of brain - dead patients in France . - pubmed
RESULTS : Seventy - one consecutive brain - dead patients admitted to the intensive care unit of the Academic Hospital of Nancy from October 1st , 1998 to September 30 , 1999 were analyzed . - pubmed
Color Doppler imaging study in patients with primary open - angle glaucoma treated with timolol 0.5 % and carteolol 2 % . - pubmed
PURPOSE : To evaluate with color Doppler imaging ( CDI ) , in patients with primary open - angle glaucoma ( PDAG ) , the possible influence on ocular hemodynamics of a beta - blocking agent with intrinsic sympathomimetic acitivity ( carteolol 2 % ) compared to a beta - blocker agent without this activity . - pubmed
A man with hereditary exostoses and high - grade non - Hodgkin ' s lymphoma of the bone . - pubmed
We present a case report of a 52 - year - old man with MCE who had a palpable mass at the left shoulder . - pubmed
Hepatoprotective action of abhrak bhasma , an ayurvedic drug in albino rats against hepatitis induced by CCl4 . - pubmed
Abhrak bhasma is a commonly used ayurvedic drug against many diseases including hepatitis . - pubmed
It is tested in albino rats using a model of hepatitis induced by a single dose of CCl4 ( 3 ml / kg body wt ) . - pubmed
[ Gastrointestinal surgery in patients with ovarian cancer ] . - pubmed
OBJECTIVES : The objectives were to assess indications as well as outcome and morbidity of gastrointestinal surgery in patients with ovarian cancer . - pubmed
METHODS : The study included 74 patients with primary ovarian cancer who had debulking surgery ( bowel surgery ) from 1987 to 2001 . - pubmed
Tophaceous gout in an amputation stump in a patient with chronic myelogenous leukemia . - pubmed
This case report describes the development of a gouty tophus at a site of remote traumatic forearm amputation in a patient with chronic myelogenous leukemia ( CML ) . - pubmed
Anatomic basis and technical aspects of a new brachial plexus avulsion injury model in the rat . - pubmed
In contrast to conventional virus isolation , all muscle samples from infected pigs were positive for viral nucleic acid by PCR , except for muscle from one animal infected with the American strain of PRRSV . - pubmed
One of the five groups was fed muscle obtained from US donor pigs that was also spiked with the American strain of PRRSV . - pubmed
Reduction of mitochondrial electron transport complex activity is restricted to the ischemic focus after transient focal cerebral ischemia in rats : a histochemical volumetric analysis . - pubmed
Micrometastases in axillary lymph nodes and bone marrow of lymph node - negative breast cancer patients -- prognostic relevance after 10 years . - pubmed
The long - term prognostic significance of immunohistochemically detectable occult tumor cells in bone marrow and axillary lymph nodes of breast cancer patients considered to be lymph node - negative in multilevel haematoxylineosin ( H&E ) lymph node sectioning was analyzed . - pubmed
Combining phacoemulsification and vitrectomy in patients with proliferative diabetic retinopathy . - pubmed
Multiple reports confirm the safety of combined surgery in patients with proliferative diabetic retinopathy . - pubmed
SUMMARY : In select patients with diabetes , combining vitrectomy with phacoemulsification and posterior capsulectomy allows patients who often have bilateral vitreoretinal disease to come to a stable postoperative vision in the eye requiring vitreous surgery much earlier than three separate procedures spread out over months or years . - pubmed
The canine animal was chosen since it can present with spontaneous bladder carcinomas mimicking human pathology . - pubmed
Primary cultures of two normal canine bladder urothelium and two canine primary bladder tumours were first studied . - pubmed
We then investigated in vivo , in two normal and two spontaneous tumour bearing dogs , the transduction of urothelial cells following direct intravesical instillation of 2.10(4 ) to 3.10(6 ) of the retroviral vector . - pubmed
RESULTS : Transduced cells were evidenced in all primary cultures of canine normal urothelium and transitional cell carcinoma . - pubmed
Bladder cryosections from tumour - bearing dogs displayed transduction of superficial layers of urothelial cancer cells without passing through lamina propria . - pubmed
CONCLUSION : These results demonstrate for the first time the feasibility of in vivo retroviral transduction of bladder cancer using a clinically relevant procedure . - pubmed
Cortical inhibition in first - degree relatives of schizophrenic patients assessed with transcranial magnetic stimulation . - pubmed
First - degree relatives of schizophrenia patients , who share various degrees of genetic vulnerability with the patients , but are free from confounds related to medication and/or florid psychosis , have not been studied to date . - pubmed
METHODS : We measured deep inspiration ( DI)-induced bronchodilation in 15 individuals with and without COPD ( 67 + /- 2.2 yrs of age , mean + /- SEM ) undergoing lobar resection for peripheral pulmonary nodule . - pubmed
The authors compared 40 subjects with essential hypotension ( mean systolic BP = 97.6 mmHg ) with 40 normotensive controls ( mean systolic BP = 124.1 mmHg ) using 6 computer - based tasks measuring tonic and phasic alertness ; selective , divided , and sustained attention ; and working memory . - pubmed
The purpose of this study is to investigate the relationship between cell death , loss of mitochondrial membrane potential ( MMP ) and reduction of metabolic rates for in vitro cultured mouse hepatocytes after acute exposure to two doses of chloroform . - pubmed
Recent outbreaks of Trypanosoma brucei rhodesiense sleeping sickness in Soroti District of eastern Uganda have demonstrated the important role cattle can play as reservoirs of this parasite . - pubmed
brucei in cattle is characterized by an acute phase with high levels of parasitaemia and a decline in PCV . - pubmed
The acute phase is followed by a chronic phase during which the PCV remains low but stable and the parasitaemia is low . - pubmed
Despite significant differences in parasitaemia , the proportion of tsetse flies that developed metacyclic infections after a first bloodmeal on the infected cattle did not differ significantly between the acute and chronic phases or the phase of mixed T. - pubmed
Its action on platelet TxA2 has highlighted its role as an anti - thrombotic agent in cardiovascular patients . - pubmed
Primary HSV infection was certain or likely in all cases , including an HSV2 superinfection of an anti - HSV1 - positive patient and two HSV superinfections of hepatitis B virus ( HBV)-related chronic liver disease . - pubmed
In these latter patients , HSV diagnosis was totally unsuspected , despite fever . - pubmed
We describe 2 patients who experienced recurrence after treatment for the primary tumor . - pubmed
Human S - cone vision : relationship between perceptive field and ganglion cell dendritic field . - pubmed
Aggressive angiomyxoma of the vulva or perineum : report of three patients . - pubmed
BACKGROUND : Aggressive angiomyxoma is a rare , locally aggressive soft tissue tumour that chiefly involves the vulvoperineal region of young female patients . - pubmed
CASES : We present three patients who each had an aggressive angiomyxoma treated initially for another presumed diagnosis . - pubmed
Two patients required immediate repeat surgical procedures for incomplete tumour excision . - pubmed
The third patient developed a recurrence two years after the initial surgery . - pubmed
In one patient , hormonal therapy was used postoperatively because the evaluation of the tumour margins was uncertain . - pubmed
Harpoon markers were used to aid in tumour localization in another patient prior to resection . - pubmed
CONCLUSION : Clinicians should consider the diagnosis of aggressive angiomyxoma when a patient presents with an atypical vulvoperineal mass , as an incorrect diagnosis may lead to repeated surgical procedures . - pubmed
Among the structural abnormalities affecting the human Y chromosome , dicentric chromosomes are the most common . - pubmed
PURPOSE : To identify vitreous proteins that were differentially expressed in patients suffering from proliferative diabetic retinopathy with active neovascularization . - pubmed
METHODS : The vitreous samples of 15 active proliferative diabetic retinopathy patients were analyzed by two - dimensional gel electrophoresis and mass spectrometry , and the results were compared with those from age - matched patients with macular hole . - pubmed
Five proteins were upregulated in the proliferative diabetic retinopathy patients , and three were downregulated ( p value & lt ; 0.05 ) . - pubmed
CONCLUSIONS : We constructed vitreous protein profiles for proliferative diabetic retinopathy patients and identified eight candidate proteins believed to be involved in the pathogenesis of proliferative diabetic retinopathy . - pubmed
METHODS : Retrospective medical record review ( 1982 to 2003 ) for patients with a diagnosis of Duane syndrome ( examined by a pediatric ophthalmologist ) who were bilaterally affected and had no prior ocular surgery . - pubmed
Eight patients treated with an extracranial - intracranial vascular bypass graft over a period of 44 months for symptomatic cavernous sinus aneurysms are reviewed . - pubmed
At a mean follow - up of 20 months , seven patients ( 87.5 % ) had an excellent outcome ( Glasgow Outcome Score 5 ) while one patient suffered a perioperative stroke . - pubmed
The results of this series seem to indicate that cerebral revascularisation is an effective treatment for patients with symptomatic cavernous sinus aneurysms . - pubmed
METHODS : Fifty - three patients ( M / F = 43/10 , 62 + /- 14 years ) with typical AFL were included . - pubmed
BACKGROUND : Leptospira are the parasitic bacterial organisms associated with a broad range of mammalian hosts and are responsible for severe cases of human Leptospirosis . - pubmed
Two patients , who had been diagnosed and treated surgically for hyoid bone insertion tendinitis , were presented in this study . - pubmed
DCs that are manipulated to present tumor antigens induce antitumor immunity in animal models and preclinical human studies . - pubmed
A discussion of 2 double - blind studies comparing risperidone and quetiapine in patients with schizophrenia . - pubmed
[ Implication of middle - mass molecule peptides of blood plasma in assessment of intoxication syndrome in patients with bacterial tonsillitis ] . - pubmed
High therapeutic efficacy of an immunomodulating drug tamerit in combined therapy of patients with bacterial tonsillitis is shown . - pubmed
The change in atrophy in relation to neutrophil infiltration was significant in Hp ( + ) patients ( P = 0.0001 ) . - pubmed
The change in atrophy in relation to neutrophil infiltration in patients with GG genotype was significant ( P = 0.002 ) . - pubmed
People were asked if they had a sore throat and/or skin sores and asked about current or recent use of antibiotics ; all throats and any pyoderma lesions were swabbed for bacterial culture . - pubmed
Myelination as assessed by conventional MR imaging is normal in young children with idiopathic developmental delay . - pubmed
MATERIALS AND METHODS : A total of 93 children ( 31 controls , 62 with idiopathic developmental delay [ IDD ] ) aged 17 to 46 months were identified on the basis of having brain MR imaging for evaluation of IDD ( cases ) or for another condition ( controls ) . - pubmed
Children with diseases that primarily affect white matter or overt intracranial lesions or malformations were excluded . - pubmed
Developmental quotients ( DQs ) were calculated for all children with IDD on the basis of clinical history , examination , and psychometric testing . - pubmed
Neuroimaging evaluation of maturity of subcortical myelination is not a marker of IDD in young children , and the isolated " finding " of delayed myelination should be interpreted with caution . - pubmed
Neisseria gonorrhoeae expresses numerous surface proteins that mediate bacterial adherence and invasion during infection . - pubmed
In contrast , fruit damage in methoxyfenozide- and lambda - cyhalothrin - treated fruit was observed earlier for resistant codling moth . - pubmed
The patient presented with an epigastric pain for two months . - pubmed
Control subjects included 65 non - SA patients admitted to the same hospital with ACS matched by age , sex and year of hospitalization . - pubmed
MMTV - induced pregnancy - dependent mammary tumors : early history and new perspectives . - pubmed
Almost 60 years ago , Foulds carefully described for the first time a particular type of mouse mammary tumor that appeared in the glands of pregnant females and disappeared shortly after delivery . - pubmed
Since then , the attention that researchers paid to the Mouse Mammary Tumor Virus ( MMTV)-induced pregnancy - dependent tumors has not vanished through the years . - pubmed
This was because the information obtained from mice carrying MMTV variants that were able to induce pregnancy - dependent tumors was meaningful for studying different aspects of mammary tumor biology . - pubmed
In the analysis of the association between tumor morphology and behavior , the mechanisms underlying progression towards autonomy , the impact of different genes during cancer initiation and development , and the relevance of host genetic background for tumor incidence and hormone - dependence , mouse strains carrying these MMTV variants have been very important tools that could not have been replaced with any other available model . - pubmed
The goal of this article is to provide a succinct chronicle of the experiments and observations made in the MMTV - induced pregnancy - dependent models that most significantly contributed to the mouse mammary tumor biology field . - pubmed
In addition , the possibility to use these MMTV variants as alternative models for analyzing mammary tumor stem cells and pregnancy - associated breast cancer in women is discussed . - pubmed
METHODS : A prospective database of 878 conservatively treated patients with ductal carcinoma in situ was analyzed . - pubmed
Among 327 excision plus radiotherapy patients , there were 59 recurrences . - pubmed
In an attempt to predict which patients develop invasive recurrences , prolonged time to recurrence was the only statistically significant factor . - pubmed
CONCLUSIONS : The median time to local recurrence for irradiated patients was more than twice as long when compared with nonirradiated patients , during which there is more time for local recurrence to progress to invasion . - pubmed
Irradiated patients had more breast scarring , making diagnosis by palpation and mammography harder . - pubmed
Irradiated patients develop invasive recurrences at a statistically higher rate than nonirradiated patients . - pubmed
We designed a cross - sectional study with 225 asymptomatic diabetic patients having no known CAD . - pubmed
A total of 109 patients ( 48.4 % ) was found to have silent myocardial ischemia . - pubmed
HIV / AIDS taking shocking toll on black community . - pubmed
LMWPEI combines low cytotoxicity with high transfection efficiency in the mouse lung in vivo , rendering it a promising strategy for pulmonary gene delivery . - pubmed
OBJECTIVES : The goal of this study was to dosimetrically compare 3 - dimensional radiotherapy ( 3DCRT ) , intensity - modulated radiotherapy ( IMRT ) , and helical tomotherapy ( TOMO ) plans for whole abdominopelvic radiotherapy ( WART ) in patients with gynecologic cancer . - pubmed
Clinical experiences will be needed for evaluation of feasibility of WART using TOMO in patients with gynecologic cancer . - pubmed
Imaging diagnosis -- enostosis - like lesion in the femur of a horse . - pubmed
An enostosis - like lesion was diagnosed in the left femur of a Swedish Warmblood horse that had a left hindlimb lameness of 3 weeks duration . - pubmed
Enostosis - like lesions should be considered as a source of pain in horses with difficult to localize , moderate to severe chronic lameness . - pubmed
RESULTS : There were 839 patients ( 138 desmoids ) without genotype and 154 ( 30 desmoids ) with genotype . - pubmed
The addition of cervical thrust manipulations to a manual physical therapy approach in patients treated for mechanical neck pain : a secondary analysis . - pubmed
OBJECTIVES : To perform a secondary analysis on the treatment arm of a larger RCT to determine differences in treatment outcomes , adverse reactions , and effect sizes between patients who received cervical thrust manipulation and those who received only nonthrust manipulation as part of an impairment - based , multimodal treatment program of manual physical therapy ( MPT ) and exercise for patients with mechanical neck pain . - pubmed
BACKGROUND : A treatment regimen of MPT and exercise has been effective in patients with mechanical neck pain . - pubmed
METHODS : Treatment outcomes from 47 patients in the treatment arm of a larger RCT , with a primary complaint of mechanical neck pain , were analyzed . - pubmed
A 32 - year - old man presented with thyroid eye disease and was found to have an orbital floor fracture on routine preoperative imaging without any antecedent relevant symptom or sign . - pubmed
To the best of the authors ' knowledge , this is the first report of an asymptomatic orbital fracture in a patient with thyroid eye disease . - pubmed
BACKGROUND : Both concomitant chemotherapy and altered fractionation radiotherapy ( RT ) have been shown to improve outcomes for patients with locoregionally advanced head and neck squamous cell carcinomas . - pubmed
Seven ( 6 % ) patients changed from cisplatin to carboplatin because of bone marrow toxicity . - pubmed
Monoammonium glycyrrhizinate inhibited the inflammation of LPS - induced acute lung injury in mice . - pubmed
In this study , the anti - inflammatory effects of MAG on lipopolysaccharide ( LPS)-induced acute lung injury ( ALI ) in mice and the possible mechanisms involved in this protection were investigated . - pubmed
INTRODUCTION : previous studies have linked hippocampal volume change and cognitive decline in older adults with dementia . - pubmed
The authors examined hippocampal volume change and cognitive change in older nondemented adults with and without major depression . - pubmed
METHODS : the sample consisted of 90 depressed individuals and 72 healthy , nondepressed individuals aged 60 years and older who completed at least 2 years of follow - up data . - pubmed
Depressed patients with hippocampal volume loss are at greater risk of cognitive decline . - pubmed
Hepatocellular carcinoma ( HCC ) is one of the most common solid cancers , representing the third cause of cancer - related death among cirrhotic patients . - pubmed
This protein was expressed in half of human cancer cell lines but barely in normal human fibroblasts tested . - pubmed
The needles of Pinus densiflora Siebold et Zuccarini , a representative Pinus species that grows in Korea , have been used in oriental traditional medicine as remedies for rheumatitis , hemorrhage , cancer , etc . - pubmed
Detection of PRRSV circulation in herds without clinical signs of PRRS : comparison of five age groups to assess the preferred age group and sample size . - pubmed
A cross - sectional study was conducted to find the most effective diagnostic approach to detect circulation of porcine reproductive and respiratory syndrome virus ( PRRSV ) . - pubmed
This result indicates that 9- to 16 - week - old pigs are the preferred age group to detect PRRS - virus , in herds without clinical signs of PRRS . - pubmed
Testing 12 blood samples in both rt - PCR and ELISA , with 6 samples in pigs 9 weeks of age and 6 samples in pigs 16 weeks of age , will lead to a cost - efficient first evaluation of the PRRSV infection - status in herds without clinical signs of PRRS . - pubmed
BACKGROUND : Despite the high prevalence of depression in people with neurological disorders , no previous study has sought to summarise existing evidence on the use of antidepressants in this population . - pubmed
METHODS : Embase , Pubmed , Psycinfo and Cochrane trial registers were searched for randomised controlled trials ( RCTs ) comparing the efficacy of antidepressant and placebo in the treatment of depression in adults with a neurological disorder . - pubmed
FINDINGS : 20 RCTs were included in the review , including patients with Parkinson ' s disease , multiple sclerosis , brain injury , epilepsy and stroke . - pubmed
INTERPRETATION : Antidepressants are effective for the treatment of depression in patients with neurological disorders but the evidence for the efficacy of antidepressants in improving quality of life , and functional and cognitive outcomes is inconclusive . - pubmed
The preparation was found to contain a low molecular - weight growth - inhibitory activity , suppressing both DNA synthesis in cultured EAC cells and EAC cell division in tumor - bearing mice . - pubmed
Respiratory syncytial virus ( RSV ) is a major cause of bronchiolitis and pneumonia in infants , the immunocompromised , and the elderly in both developed and developing countries . - pubmed
Epidemiological trends and clinical comparisons of Mycobacterium tuberculosis lineages in Thai TB meningitis . - pubmed
Mycobacterium tuberculosis ( MTB ) strains were isolated from cerebrospinal fluids collected from individual tuberculous meningitis ( TBM ) patients from 1996 to 2007 ( n = 184 ) and characterised based on IS6110 - restriction fragment length polymorphism ( RFLP ) , spoligotyping , Mycobacterium interspersed repetitive unit - variable number of tandem repeat ( MIRU - VNTR ) and large sequence polymorphisms ( LSPs ) . - pubmed
Valproic acid and sodium valproate for neuropathic pain and fibromyalgia in adults . - pubmed
MAIN RESULTS : We included three studies , two in diabetic neuropathy ( 42 participants treated with valproate , 42 with placebo ) , and one in post - herpetic neuralgia ( 23 treated with divalproex sodium , 22 with placebo ) . - pubmed
Already , a library of magnetic nanoparticles has been developed , in which a wide range of targets , including DNA / mRNA , proteins , small molecules / drugs , bacteria , and tumor cells , have been quantified . - pubmed
Even though outcomes are excellent , with reported 5 - year patient and graft survival exceeding 90 % and 80 % , 80 % and 75 % , 72 % and 65 % for PBC , PSC , and AIH , respectively , the issue of recurrent autoimmune liver disease after orthotopic liver transplantation is increasingly recognized as a cause of graft dysfunction , death , and need for retransplantation . - pubmed
Orally administered AEE788 prolonged survival of mice bearing ependymoma - SC - driven orthotopic xenografts from 56 to 63 days , close to statistical significance ( log - rank p=0.06 ) . - pubmed
Accelerated mammary tumor onset in a HER2 / Neu mouse model exposed to DDT metabolites locally delivered to the mammary gland . - pubmed
BACKGROUND : The association of DDT ( dichlorodiphenyltrichloroethane ) with breast cancer is controversial , but animal studies directly linking DDT to risk are lacking . - pubmed
OBJECTIVES : We aimed to determine whether developmental exposure to p , p - DDE stored in adipose tissue surrounding the cancer - prone mammary epithelium of MMTV - Neu mice influences tumor development . - pubmed
CONCLUSIONS : p , p - DDE exposure at concentrations relevant to human exposure accelerates mammary carcinogenesis in mice , possibly through hormonal and/or other actions . - pubmed
Reversible blindness : severe pneumococcal induced uveitis following septicaemia . - pubmed
This study illustrates the case of a middle - aged woman who presented with sepsis and purpura fulminans , found to be due to Streptococcus pneumoniae infection . - pubmed
She later developed blindness from a dramatic ocular inflammatory response provoked by pneumococcal antigens . - pubmed
METHODS : The levels of the different markers were measured by enzyme - linked immunosorbent assay in pleural fluids from patients with MPM ( n = 61 ) , adenocarcinomas ( ADCA , n = 25 ) , or with benign pleural effusions ( BPE , n = 15 ) . - pubmed
There was a trend toward increasing inadvertent PAN injury rate in patients with high body mass index and large tumours . - pubmed
Most of the 12 patients with potentially active erectile function before the operation recovered this function , and only one patient ( 7 % ) with PAN injury was still judged as inactive 12 months after surgery . - pubmed
CONCLUSION : The proportion of patients with sexual dysfunction after LTME is low . - pubmed
[ Experience of invasive surgical treatment of renovascular hypertension in children ] . - pubmed
OBJECTIVES : To document any consistent clinical findings in a large cohort of patients with whiplash associated disorder . - pubmed
We performed a cross - sectional study of 19 women aged 22 - 49 years , including 9 SLE patients in clinical remission taking & lt;=5 mg prednisone and 10 matched controls . - pubmed
Incubation of human dopaminergic SH - SY5Y cells with amurensin G attenuated the cellular toxicities of rotenone in a model of Parkinson ' s disease . - pubmed
We report the case of a patient with a history of recent head trauma , who came to our observation for acute - onset mental confusion secondary to severe hyponatremia due to SIADH of combined etiology . - pubmed
In the research setting , some of these agents are combined in a single device , an approach that may become the standard treatment for many patients with chronic obstructive pulmonary disease . - pubmed
A 54 - year - old man with a left saphenous varicose vein underwent EVLT surgery . - pubmed
ANIMALS : Twenty - six client - owned dogs : 15 dogs with clinical signs of cervical hyperesthesia ( group 1 ) , and 11 dogs without of clinical signs ( group 2 ) . - pubmed
RESULTS : All dogs without clinical signs had symmetrical syringomyelia , whereas in the group with pain , 6 dogs had symmetrical and 9 dogs had asymmetrical syringomyelia . - pubmed
There was no significant difference between the mean width of the syringomyelia in dogs with or without pain . - pubmed
BACKGROUND : In ethno - medicinal practices , the roots of Cissampelos pareira(Patha ) are used in the treatment of various ailments related to urinary problems and skin infections , and in tumorinhibitor activity , antibacterial , antimalarial , diuretic activity , anticonvulsant activity etc . - pubmed
PATIENT SAMPLE : Of a consecutive series of 38 patients with idiopathic thoracolumbar scoliosis , Lenke type 5 , 29 patients were included in the study . - pubmed
This study collected patients with TC treated in 5 high - volume Italian Thoracic Surgery Institutions . - pubmed
METHODS : A multicenter retrospective study of patients operated for TC between 2000 and 2011 was conducted . - pubmed
RESULTS : Four hundred and seventy - eight patients underwent surgery for thymic malignancies : 40 of them ( 8.4 % ) had TC . - pubmed
Adjuvant radio / chemotherapy was offered to 37 patients , according to the type of surgical resection and tumor invasiveness . - pubmed
Recurrences developed in 10 patients . - pubmed
Comparative pharmacokinetics of borneol in cerebral ischemia - reperfusion and sham - operated rats . - pubmed
METHODS : The rats were divided into two groups , ischemia - reperfusion ( IR ) and sham - operated ( SO ) rats . - pubmed
RESULTS : After administration of borneol , the maximum plasma concentration ( Cmax ) and area under the curve ( AUC ) values in stroke rats significantly increased by 302 % and 275 % , respectively , compared with the SO rats , and the same phenomenon appeared after administration of XNJ . - pubmed
Prophylactic effectiveness of suplatast tosilate in children with asthma symptoms in the autumn : a pilot study . - pubmed
METHODS : This study compared the prophylactic effectiveness of suplatast tosilate with that of mequitazine in children with asthma symptoms , which is usually exacerbated in the autumn . - pubmed
The study group comprised 27 children aged 2 to 15 years who required treatment for asthmatic attacks during the past year and tested positive at least for mite allergen in the preceding autumn . - pubmed
Our aim was to examine the incidence , characteristics , reasons , and risk factors for unplanned revision surgery in spinal deformity patients treated at one institution . - pubmed
Epidemiological studies are weighted towards the presence of BPH having a greater risk for a man to develop PCa in his lifetime ; however , a conclusion of causality can not be confidently stated . - pubmed
Animal models of poststroke fatigue ( PSF ) and poststroke depression ( PSD ) would facilitate the study of these symptoms . - pubmed
We used different rat strains to evaluate stroke - induced changes in behavior in hopes that interstrain differences would provide insights into the biological basis of these symptoms . - pubmed
Male Lewis , Wistar , and Sprague - Dawley ( SD ) rats underwent experimental stroke . - pubmed
Stroke also led to an increase in learned helplessness in Lewis rats . - pubmed
In summary , different patterns of behaviors emerge in different rat strains after stroke . - pubmed
Diagnostic utility of F waves in clinically diagnosed patients of carpal tunnel syndrome . - pubmed
METHODS : Median and ulnar nerves sensory and motor conduction , median and ulnar nerves F - wave studies were carried out bilaterally in 125 clinically diagnosed patients of carpal tunnel syndrome . - pubmed
BACKGROUND : Pediatric and adult anxiety disorder patients exhibit attention bias to threat and difficulty disengaging attention away from threat . - pubmed
The aim of the present study was to examine the neural correlates of these processes in children and adolescents with anxiety disorders . - pubmed
METHODS : Participants with an anxiety disorder 7 to 19 years old ( n = 34 ) and typically developing controls ( n = 35 ) underwent fMRI scanning . - pubmed
RESULTS : Analysis of ex vivo cultures from normal looking SQ from controls , RE patients , and BE patients revealed no significant differences in the number and phenotypes of T - cells . - pubmed
The recognition of human papilloma virus ( HPV ) as the causal agent of cervical cancer in the early 80 's changed the prevention paradigms . - pubmed
Due to the existence in Chile of a well - organized nationwide CC prevention program , the replacement of a low - sensitivity screening test such as the Papanicolau test with a highly sensitive one such as HPV detection , could quickly improve the effectiveness of the program . - pubmed
BACKGROUND : Delayed hematoma expansion is common in intracerebral hemorrhage ( ICH ) patients using warfarin . - pubmed
This study aims to clarify whether dabigatran increases the risk of delayed hematoma expansion in a rat ICH model . - pubmed
CONCLUSIONS : This experimental study of a rat ICH model indicates that dabigatran - related ICH may not increase the risk of delayed hematoma expansion . - pubmed
We present a patient with a fistula that developed 23 years after hysterectomy and radiotherapy . - pubmed
METHODS : Thirty patients with early onset chronic depression were compared with 30 patients with episodic depression and 30 healthy , never - depressed controls in terms of self - reported cognitive - behavioral ( social and non - social ) and emotional avoidance . - pubmed
RESULTS : Chronically depressed patients reported more avoidance than healthy controls in each of the measures . - pubmed
Furthermore , general emotion avoidance and behavioral - social avoidance were positively correlated with levels of depression in chronically depressed patients . - pubmed
METHODS : Clinical records of 14 outpatients and inpatients that visited the First Hospital of Jilin University ( Changchun , China ) for management of burn injuries caused by cupping therapy were retrospectively reviewed . - pubmed
We found that TSA significantly inhibited lung tumorigenesis in Grg1 transgenic mice ( p & lt ; 0.01 ) . - pubmed
Among the IHCIS patients 60 years of age or older and full year of eligibility during 2010 , there were 898 VaD patients , from which 63.6 % were women . - pubmed
Concurrent presence of cerebrovascular disease , atherosclerosis , heart failure , and atrial fibrillation were found at 12.6 , 4.6 , 2.8 , and 1.7 times higher in VaD patients , respectively . - pubmed
METHODS : This was a prospective longitudinal study in women with singleton pregnancies identified by screening at 11 + 0 to 13 + 6 weeks ' gestation as being at high - risk of PE . - pubmed
RESULTS : A total of 1069 samples were analyzed in 234 women , including 172 who remained normotensive , 18 who developed GH , 22 who developed preterm PE and 22 who developed term PE . - pubmed
Freshwater harmful algal blooms and cyanotoxin poisoning in domestic dogs . - pubmed
Patients with occult lymph node metastasis in endometrioid - type endometrial cancer ( EC ) are prone to the development of recurrences and have worse outcomes compared with patients without lymph node metastasis . - pubmed
A univariate analysis of differentially expressed genes , proteins and clinicopathological parameters ( including myometrial invasion and tumor grade ) was performed , comparing EC patients with and without lymph node metastasis ( n=262 patients from The Cancer Genome Atlas ) . - pubmed
In addition , this compound also showed considerable protection against pilocarpine induced status epilepticus in rats . - pubmed
Vi conjugate typhoid vaccine conferred 100 % protection against typhoid fever in 1765 children 6 months to 12 years of age with high immunogenicity in a subgroup from the vaccine arm . - pubmed
METHODS : In this phase 2 , single - blind , dose - ranging , adaptive randomised trial , we enrolled boys and men with uncomplicated P falciparum malaria at the Malaria Research and Training Centre ( MRTC ) field site in Ouelessebougou , Mali . - pubmed
INTERPRETATION : A single dose of 0 25 mg / kg primaquine , given alongside dihydroartemisinin - piperaquine , was safe and efficacious for the prevention of P falciparum malaria transmission in boys and men who are not deficient in G6PD . - pubmed
This study examined whether individuals with rapid eye movement sleep behavior disorder who do not have a diagnosis of PD show abnormalities in gait initiation that resemble the impairments observed in PD and whether there is a relationship between these deficits and the level of rapid eye movement sleep without atonia . - pubmed
METHODS : Gait initiation and polysomnography studies were conducted in 4 groups of 10 participants : rapid eye movement sleep behavior disorder , PD with and without freezing of gait , and controls . - pubmed
CONCLUSIONS : These results provide evidence that people with rapid eye movement sleep behavior disorder , prior to a diagnosis of a degenerative neurologic disorder , show alterations in the coupling of posture and gait similar to those seen in PD . - pubmed
In patients with higher weight gain at RRT initiation , mortality and dialysis dependency were significantly lower with continuous RRT ( HR 0.54 , 95 % CI 0.29 - 0.99 ; p = 0.05 ) . - pubmed
Conversely , this technique appeared to be deleterious in patients without shock ( HR 2.24 , 95 % CI 1.24 - 4.04 ; p = 0.01 ) . - pubmed
Six - month mortality and persistent renal dysfunction were not influenced by the RRT modality in patients with dialysis dependence at ICU discharge . - pubmed
RESULTS : During follow - up ( median 119.0 , range 6.6 to 161.3 months ) , tumor recurrence was detected in 50 patients ( 43.1 % ) , and local recurrence developed as a first failure site in 13 patients ( 11.2 % ) . - pubmed
METHODS : We performed a retrospective study with 116 locally advanced rectal cancer patients who underwent total mesorectal excision ( TME ) followed by postoperative concurrent chemo - radiation therapy ( CCRT ) . - pubmed
METHODS : Adult patients with isolated fresh unstable metacarpal and phalangeal fractures who met the inclusion criteria were enrolled into this prospective study from July 2013 . - pubmed
Animal models have implicated an integral role for coagulation factors in neuroinflammatory diseases such as multiple sclerosis ( MS ) beyond their role in hemostasis . - pubmed
However , few researches compared the expression and functions of both oncogenes in human malignant tumors at same time . - pubmed
This question is of crucial importance given the recent demonstration in both animals and humans that a period of blindness early in life permanently affects the brain networks dedicated to visual , auditory , and multisensory processing [ 1 - 16 ] . - pubmed
To address this issue , we compared a group of adults who had been treated for congenital bilateral cataracts during early infancy with a group of normally sighted controls on a task requiring simple detection of lateralized visual and auditory targets , presented alone or in combination . - pubmed
However , in comparison to controls , cataract - reversal patients were faster at processing simple auditory targets and showed differences in how they shifted attention across modalities . - pubmed
In total , 30 children with ASD ( mean age : 7.72 + - 2.65 y ; range ; 4 - 12 y ) and 30 healthy children ( mean age : 8.4 + - 2.66 y ; range : 4 - 12 y ) , including males and females , were matched for age , gender , and body mass index ( BMI ) . - pubmed
We now show that this effect of T2S is also manifest upon infection of human THP-1 macrophages and peripheral blood monocytes but does not occur during infection of murine macrophages . - pubmed
[ The modern possibilities for the treatment of the patients presenting with benign and tumour - like diseases of the larynx ] . - pubmed
Rehabilitation of the patients presenting with benign and tumour - like diseases of the larynx ( BLT ) is currently a serious challenge for modern otorhinolaryngology in view of the high prevalence of this pathology . - pubmed
Dysphonia is a leading clinical symptom of the diseases that considerably deteriorates the quality of life of the patients . - pubmed
The treatment of the patients presenting with benign and tumour - like diseases of the larynx requires a combined approach including the surgical , therapeutic , and phonopedic modalities for the rehabilitation of the vocal function . - pubmed
This article presents a review of the literature on the modern high - energy techniques for the treatment of the patients presenting with benign and tumour - like diseases of the larynx , The advantages and disadvantages of each method are discussed . - pubmed
The therapeutic potential of 177Lu - DTPA - sdAb was compared with that of 177Lu - DTPA - rituximab and unlabeled rituximab in mice bearing hCD20pos tumors . - pubmed
Objective : To compare the degree of pain relief between high - dose ( 40 mg of triamcinolone acetonide ) and low - dose ( 20 mg of triamcinolone acetonide ) corticosteroid injections in patients with severe pain due to adhesive capsulitis . - pubmed
Subjects : A total of 32 patients who were diagnosed with adhesive capsulitis and who expressed severe pain intensity , 8 or more points on a numeric rating scale ( NRS ) . - pubmed
Conclusions : Injection of 20 mg of triamcinolone acetonide is sufficient to elicit symptom relief in patients with severe adhesive capsulitis ; hence , 20 mg of triamcinolone acetonide can be recommended in patients with adhesive capsulitis with severe pain . - pubmed
Hippocampal extracellular matrix alterations contribute to cognitive impairment associated with a chronic depressive - like state in rats . - pubmed
Patients with depression often suffer from cognitive impairments that contribute to disease burden . - pubmed
We used social defeat - induced persistent stress ( SDPS ) to induce a depressive - like state in rats and then studied long - lasting memory deficits in the absence of acute stressors in these animals . - pubmed
Our data reveal a causal link between increased hippocampal extracellular matrix and the cognitive deficits associated with a chronic depressive - like state in rats exposed to SDPS . - pubmed
Introduction : Acute respiratory distress syndrome ( ARDS ) is a devastating pulmonary condition in the critically ill patient . - pubmed
RESULTS : Of 100 included patients , ten ( median GA 27.5 weeks [ 24.6 - 29.4 ] , BW 1010 g [ 775 - 1630 ] ) developed NEC . - pubmed
A 49 - year - old woman was admitted to our hospital with recurrent episodes of paresthesia attacks evolving in 5 to 15 minutes from the left hand to the left leg through the left trunk . - pubmed
Because we assumed the cause of the recurrent sensory attack to be meningeal inflammation around the primary somatosensory cortex , we treated this patient by increasing the dose of prednisolone . - pubmed
OBJECTIVES : The aim of this study was to compare skeletal maturity between the groups depending on the malocclusion as well as to define the optimal timing for particular orthodontic treatment procedures in children with miscellaneous types of malocclusion and compare it with the duration of treatment proposed by the National Health Fund ( NFZ ) . - pubmed
Vehicle- or ethanol- ( 1.6 g / kg ) treated mice were subjected to sham or 15 % total body surface area scald burn . - pubmed
Taken together , our results suggest intravenous MSCs treatment can diminish systemic inflammation , lessen hepatic damage , and decrease liver and lung apoptosis and inflammation , indicating MSCs as a novel therapy for restoring homeostasis of multiple organ systems in intoxicated burn patients . - pubmed
RESULTS : Most children with midline spikes had seizures ( 91 % ) , with an equal predisposition to focal or generalized seizure semiology . - pubmed
In patients with abnormal neuro - maging , deep gray or white matter abnormalities were more frequent in the midline group ( 41 % vs. 13 % , P = 0.02 ) . - pubmed
The genome revealed that the G+C content was 63.9 mol% and the DNA - DNA relatedness values between strain WN007 T and the type strains of P. - pubmed
Targeted Diet Modification Reduces Multiple Sclerosis - like Disease in Adult Marmoset Monkeys from an Outbred Colony . - pubmed
Experimental autoimmune encephalomyelitis ( EAE ) in common marmosets is a translationally relevant model of the chronic neurologic disease multiple sclerosis . - pubmed
The reduced EAE susceptibility after the dietary change coincided with reduced Callitrichine herpesvirus 3 expression in the colony , an EBV - related gamma1 - herpesvirus associated with EAE . - pubmed
Spinal cord demyelination , a classical hallmark of the disease , was significantly lower in new - diet monkeys than in monkeys reverted to the original diet . - pubmed
2 '- fucosyllactose ( 2 - FL ) , one of the most abundant human milk oligosaccharides ( HMOs ) , has received much attention due to its health - promoting activities , such as stimulating the growth of beneficial gut microorganisms , inhibiting pathogen infection , and enhancing the host immune system . - pubmed
Dexmedetomidine Ameliorates Sleep Deprivation - Induced Depressive Behaviors in Mice . - pubmed
In this study , the action of dexmedetomidine on sleep deprivation - induced depressive behaviors was investigated using mice . - pubmed
METHODS : For the inducing of sleep deprivation , the mice were placed inside a water cage containing 15 platforms and filled with water up to 1 cm below the platform surface for 7 days . - pubmed
One day after sleep deprivation , dexmedetomidine at the respective dosage ( 0.5 , 1 , and 2 mug / kg ) was intraperitoneally treated into the mice , one time per a day during 6 days . - pubmed
The patient was asymptomatic and therefore continued on to chemotherapy treatment for the large B - cell lymphoma . - pubmed
BACKGROUND : The added value of cardiopulmonary exercise testing ( CPET ) in the follow - up of patients with stable pulmonary arterial hypertension ( PAH ) remains undefined . - pubmed
METHODS : Idiopathic , heritable , and drug - induced PAH patients free from clinical worsening ( CW ) after 1 year of treatment were enrolled in derivation ( n = 80 ) and validation ( n = 80 ) cohorts at an interval of 6 years and followed for 3 years . - pubmed
CONCLUSIONS : The combinations of baseline VO2 peak and change in CI during follow - up is important in prognostication of low - risk patients with idiopathic , heritable , and drug - induced PAH . - pubmed
OBJECTIVE : To present the essential guidelines for pharmacological management of patients with psychomotor agitation in Brazil . - pubmed
METHODS : We are presenting the case of a 62 - year - old male patient suffering from 63 - mm juxtarenal aortic aneurysm . - pubmed
Inflammatory responses and biological characteristics of human osteosarcoma cells and umbilical cord blood mononuclear cells in co - cultured microenvironment . - pubmed
Moreover , the results indicated that these two evaluation methods enabled more accurate determination of severity and the spared capabilities of AD patients . - pubmed
To better understand the influence of crossover dynamics on WNV transmission , we examined environmental and mosquito abundance data , as well as mosquito infection rates and human disease cases from 2016 to 2018 . - pubmed
Therefore , the purpose of this study is to elucidate the role of the multifidus ( MF ) and psoas major ( PS ) muscles in maintaining global spinal alignment in patients with lumbar spinal stenosis ( LSS ) and/or degenerative spondylolisthesis ( DS ) , and to analyze whether each muscles ' cross - sectional area ( CSA ) correlates with whole - body SMM using bioimpedance analysis ( BIA ) . - pubmed
METHODS : We retrospectively evaluated 140 patients who were hospitalized for surgery to treat LSS and/or DS . - pubmed
BACKGROUND : The rate of thyroid cancer in patients with hyperthyroidism is reported to be rare , and patients with toxic thyroid nodules do not routinely undergo fine - needle aspiration ( FNA ) to evaluate for malignancy . - pubmed
However , higher rates of malignancy in hyperthyroid patients may exist than previously reported . - pubmed
This study examines the rate of malignancy in patients with hyperthyroidism who have undergone thyroidectomy . - pubmed
METHODS : A retrospective review of prospectively collected data of 138 patients with hyperthyroidism who underwent thyroidectomy at a single institution was performed . - pubmed
Patients were divided into three groups : Graves ' disease ( n = 80 ) , toxic multinodular goiter ( n = 46 ) , and toxic solitary nodule ( n = 12 ) . - pubmed
RESULTS : Of 138 patients , 22 % ( 31/138 ) were found to have malignancy on final pathology . - pubmed
The breakdown of malignancy by hyperthyroid condition was as follows : 16 % in Graves ' disease , 24 % in toxic multinodular goiter patients , and 50 % in toxic solitary nodule patients . - pubmed
CONCLUSIONS : There is a clinically significant rate of malignancy seen in patients who undergo thyroidectomy for hyperthyroidism . - pubmed
Patients with distinct thyroid nodules in the presence of hyperthyroidism may have the highest rates of malignancy and should undergo appropriate workup with ultrasound and FNA to exclude underlying malignancy . - pubmed
Transcranial direct current stimulation in patients with obsessive compulsive disorder : A randomized controlled trial . - pubmed
Neuroimaging studies have identified dysfunctions within the orbito - fronto - striato - pallido - thalamic network in patients with OCD . - pubmed
METHODS : In a randomized sham - controlled double - blind study , 21 patients with OCD were assigned to receive ten 20 - min sessions ( two sessions per day ) of either active ( 2 mA ) or sham tDCS . - pubmed
BACKGROUND : Metastatic castration - resistant prostate cancer ( mCRPC ) is incurable , with most patients surviving less than 3 years . - pubmed
OBJECTIVE : To describe the patient demographics , disease characteristics , treatment patterns , and outcomes in a cohort of Veterans diagnosed with mCRPC in the Veterans Health Administration . - pubmed
Following mCRPC diagnosis , the most common first - line therapies in Epoch 1 patients were docetaxel ( 83 % ) and abiraterone ( 9 % ) , whereas Epoch 2 patients mainly received abiraterone ( 47 % ) , docetaxel ( 36 % ) , and enzalutamide ( 15 % ) . - pubmed
The tumor inhibition efficiency of DiLNs in combination with immune checkpoint inhibitor antibody was studied in syngeneic D4 M animal model . - pubmed
Comparison between the toxicity profile of fluorouracil versus capecitabine concomitant with radiotherapy in patients with non - metastatic rectal cancer . - pubmed
High proportion of unknown HIV exposure status among children aged less than 2 years : An analytical study using the 2015 National AIDS Indicator Survey in Mozambique . - pubmed
BACKGROUND : Determination of the human immunodeficiency virus ( HIV ) exposure status in infants and young children is required to guarantee timely diagnosis and access to appropriate care . - pubmed
Prophylaxis treatment of COVID-19 patients with low molecular weight heparin ( LMWH ) is important to limit coagulopathy . - pubmed
A report of probable paroxysmal sympathetic hyperactivity syndrome in a patient with necrotizing fasciitis . - pubmed
VAL , DIC , MEL , VAL + MEL and VAL + DIC produced anticonvulsant effect and mitigated inflammation and oxidative stress in PTZ - kindled mice . - pubmed
PURPOSE : Patients with Graves ' orbitopathy can present with asymmetric disease . - pubmed
New patients presenting over a 4 month period with a diagnosis of Graves ' orbitopathy were included . - pubmed
Patients were categorized as having asymmetric , symmetric , and unilateral Graves ' orbitopathy . - pubmed
Sudden Cardiac Arrest and Malignant Ventricular Tachycardia in an 8 - Year - Old Pediatric Patient Who Has Hemolytic Uremic Syndrome Associated with Shiga Toxin - Producing Escherichia coli . - pubmed
Gastrointestinal , neurological , pancreatic , hepatic , and cardiac dysfunction are extrarenal manifestations of hemolytic uremic syndrome associated with Shiga toxin - producing Escherichia coli ( STEC - HUS ) . - pubmed
Comparative analysis of presentation and outcome after liver resection of patients with hepatocellular carcinoma with and without HIV . - pubmed
OBJECTIVE : Evidence shows that HIV infection may affect the survival outcome of patients with hepatocellular carcinoma ( HCC ) . - pubmed
Here , we aimed to determine whether HIV affected the overall survival ( OS ) of patients with HCC in China and ascertain the risk factors . - pubmed
The death rate due to tumor recurrence and liver failure in the HIV - positive patients were apparently higher than those of the HIV - negative patients ( tumor recurrence , 42.3 % vs. 17.3 % , P = 0.016 ; liver failure , 19.2 % vs. 2.7 % , P = 0.012 , respectively ) . - pubmed
CONCLUSIONS : HIV - positive subjects with HCC have poorer survival outcome than their HIV - negative counterparts , with tumor recurrence and liver failure as the main causes of death . - pubmed
Despite adequate curative therapy , HIV serostatus is associated with decreased survival of patients with HCC , independent of symptomatic presentation , tumor staging , and liver function . - pubmed
METHODS : Our trauma registry was reviewed for patients with a hemothorax admitted to our level 1 trauma center from 1/1/00 to 4/30/19 . - pubmed
Patients were included in the delayed group if they received a drainage procedure > 24 hours after injury . - pubmed
These patients were matched 1:1 by chest abbreviated injury score to patients who received drainage < 24 hours from injury . - pubmed
RESULTS : A total of 19 patients with 22 hemothoraces received delayed drainage . - pubmed
The polarization of monocytes into macrophages that possess anti - inflammatory and pro - angiogenic properties could provide a novel therapeutic strategy for patients who are at a high risk for developing heart failure following myocardial infarction ( MI ) . - pubmed
METHODS : Forty - one and 49 consecutive atrial fibrillation patients underwent 2nd - CB and 4th - CB PVIs using 28 - mm balloons and short freeze strategies . - pubmed
During the replication a pathogenic and a non - pathogenic strain of mouse cytomegalovirus in mouse embryo cells , three types of progeny virus particles were observed in both cases ; the virus yields of the two strains differed considerably . - pubmed
The main purpose of our experimental series was to induce , in experimental animals , diffuse pulmonary fibrosis resembling that in human lungs . - pubmed
Fourteen children with viral infection of the central nervous system have been examined with respect to their function of humoral immunity . - pubmed
These three children showed complications in the course of infection . - pubmed
Corneocytes from skin of patients with allergic contact dermatitis differed from those of normal skin : they were 15 % smaller and of irregular shape with asymmetrical trabeculae ; 50 % were nucleated and about 3 times as many cells were collected per cm2 skin surface . - pubmed
In naive rats depression of spontaneous discharge activity was the predominant effect of low doses of phoretically applied morphine . - pubmed
Correlation of detection of infectious DNA - protein complexes with persistence of virus in simian adenovirus SA7 - induced tumor cells . - pubmed
Primary tumors induced in newborn hamsters by simian adenovirus SA7 were investigated in transfection experiments . - pubmed
SA7 tumor cells serially passaged either in tissue culture or in hamsters yielded infectious DNA complexes much less frequently and appeared to evolve into nonyielder cell lines . - pubmed
These inhibitor(s ) are found in ascites from ovarian cancer patients and are detected in very low amounts in the ascites from patients with nonmalignant hepatic disease . - pubmed
The method described appears promising in terms of efficiency , reduction in the costs and technical procedures during treatment of human infertility . - pubmed
From genes to antibodies : the antipeptide approach to the immunocytochemical study of human malignant lymphoproliferative diseases . - pubmed
PURPOSE : To evaluate immediate postoperative results in children with congenital heart disease and decreased pulmonary blood flow who underwent a systemic to pulmonary shunt . - pubmed
Mitral balloon valvotomy using the Inoue balloon technique for selected patients with severe pliable rheumatic mitral valve stenosis : immediate and short - term results . - pubmed
We selected 40 patients with severe symptomatic rheumatic mitral stenosis for balloon valvotomy using the Inoue balloon technique . - pubmed
Five patients developed mild mitral regurgitation and in one patient the degree of mitral regurgitation increased from mild to moderate . - pubmed
The resurgent strain , designated A / USSR / 90 / 77(H1N1 ) , caused world pandemics , attacking ( almost exclusively ) persons who had been born since the 1950 - 1951 northern winter and causing negligible mortality . - pubmed
MAIN OUTCOME MEASURE : The A / USSR / 90 / 77 strain and its close successor , A / Brazil / 11 / 78 , attacked mainly the young , whose previous exposure to H1N1 antigens had been minimal or zero . - pubmed
Sixteen patients were considered to have moderate to severe brain lesions . - pubmed
One patient suffered a right temporal hemorrhage following cannulation of the left common carotid artery . - pubmed
To analyze left atrial ( LA ) pump function in normal subjects , in patients with essential hypertension and in patients with a healed myocardial infarction , LA dimension ( aortic - root echogram ) and pressure ( catheter - tip manometer ) were simultaneously recorded in 25 patients ( 8 normal subjects , 7 with hypertension and 10 with myocardial infarction ) . - pubmed
Prodromal symptomatology was investigated , by means of a modified version of Paykel 's Clinical Interview for Depression , in 15 outpatients at their first episode of primary major depressive disorder . - pubmed
Poisoning from Thevetia nerifolia ( yellow oleander ) - pubmed
Renal artery stenosis in patients with aortic dissection : increased prevalence . - pubmed
The authors retrospectively analyzed the prevalence of renal artery stenosis in 63 consecutive patients with aortic dissection who underwent thoracic and abdominal aortography . - pubmed
Ten patients ( 16 % ) had renal artery stenosis , five with atherosclerosis and five with fibromuscular lesions . - pubmed
In this series , emergent PTRA successfully controlled the hypertension in one patient with a type B dissection , resulting in an excellent clinical outcome . - pubmed
Angiography should be routinely performed on patients with aortic dissections to evaluate for renal artery stenosis . - pubmed
Not all patients with supraventricular arrhythmias require invasive studies , however , since empiric drug trials will often be adequate for management . - pubmed
Innovations that include surgical and catheter ablations of tachycardia pathways and antitachycardia pacing devices hold great promise and in the future , will provide nonpharmacologic options for patients poorly controlled by or intolerant of drug therapy . - pubmed
A girl presenting with an enlargement of the spleen , thrombocytopenia and microangiopathic hemolytic anemia at birth was studied , and a splenic hemangioma was diagnosed . - pubmed
The authors report the radiological features of a patient , believed to be unique in the literature , of multiple aneurysms of the lateral - most lenticulostriate artery in a normotensive , non - diabetic , young , female patient who presented with left basal ganglionic hematoma and showed spontaneous obliteration of these aneurysms , on follow - up angiography . - pubmed
The long - term antihypertensive activity and acceptability of a new beta - blocking agent tertatolol ( T ) ( 5 mg once daily ) was assessed in a 12 - month ( M0 - M12 ) open study , in 110 out - patients ( 64 men , 46 women , mean age 53.5 + /- 1.0 years ) , presenting with stable placebo - resistant hypertension ( HT ) ( 95 less than or equal to diastolic blood pressure less than 130 mm Hg on 3 occasions during a 1 - month placebo run - in period ) . - pubmed
The older child undergoing intermediategrade surgery requires the best available analgesia , but without sedation and nausea . - pubmed
The advantages of both these methods are then available for the benefit of the child , and the value of regional analgesia is further enhanced when supplementary intramuscular or oral analgesia is given regularly at specific times so that pain is prevented rather than relieved . - pubmed
[ 56 - year - old man with the clinical picture of intestinal obstruction ] . - pubmed
[ Kidney echo scanning in patients with chronic kidney failure ] . - pubmed
Pulmonary emboli in burned patients . - pubmed
The incidence of and prophylaxis against clinically important pulmonary emboli ( PE ) in burned patients is an often discussed problem . - pubmed
To study its magnitude , all patients admitted with acute burns were followed for clinical evidence of thromboembolism : 2,106 patients were evaluated ( 1,439 adults ) . - pubmed
Six adults ( 0.4 % ) sustained a PE : none died . - pubmed
Only two patients had significant risk factors ; they were obese with leg burns . - pubmed
The incidence of pulmonary emboli and resulting morbidity do not justify routine prophylactic heparinization of all burned patients . - pubmed
It was detected 5 years later when the patient developed persistent low back pain . - pubmed
Effect of maternal vaccination on the susceptibility of growing pigs to leptospiral infection . - pubmed
Twelve pigs , 4 derived from unvaccinated sows and 8 from sows vaccinated against leptospirosis , were challenged intravenously at 8 weeks of age with leptospires of serovar pomona . - pubmed
All of the pigs derived from unvaccinated sows developed leptospiraemia and leptospiruria and showed strong serological responses . - pubmed
In a prospective series of 66 patients with uretero - pelvic stenosis ( " genuine hydronephrosis " ) the clinical data and the results of treatment were registered . - pubmed
At 7 days after MRMT-1 inoculation at the thigh of 5 week - old female SD rats , the tumor was treated cryosurgically by 2 cycle freezing , contact method at -170 degrees C. Weights of thymus and the spleen , histological findings of lumbar lymph nodes , PHA - induced blastogenesis of lymphocytes obtained from lumbar lymph nodes or peripheral blood , and resistance rate to tumor re - challenge were examined at 1 , 3 , 6 , 10 and 17 week(s ) after cryosurgery . - pubmed
When human diploid fibroblasts , TIG-1 , reached the end of their proliferative lifespan in vitro , they still could synthesize proteins with molecular weight of about 70,000 , 85,000 and 116,000 following the heat shock at 46 degrees C for 10 min as well as young cells did so . - pubmed
Lack of correlation between occlusion and reperfusion arrhythmias in the cat . - pubmed
Recently it has been stated that in dogs absence of arrhythmias during coronary artery occlusion identifies a subgroup at almost no risk for developing ventricular fibrillation ( VF ) during reperfusion . - pubmed
In order to reexamine this problem the left anterior descending coronary artery was occluded for 20 minutes in 41 anesthetized cats ; the incidence and type of arrhythmias during occlusion and during the first minute of reperfusion were analyzed . - pubmed
Five animals had VF during occlusion and were not resuscitated . - pubmed
Twenty animals had ischemic arrhythmias , and among them the incidence of reperfusion VF was 50 % . - pubmed
Sixteen animals did not have ischemic arrhythmias , but they did have a very similar incidence of reperfusion VF ( 44 % ) . - pubmed
It has been shown in experiments on white male rats that there is a correlation between hypoxia tolerance and the rate of metabolism in brain tissue . - pubmed
Animals with varying tolerance to hypoxia differed also in the acid - base balance of venous blood outflowing from the brain . - pubmed
While adapting to hypoxia animals with high individual tolerance developed the main metabolic changes in the reticular formation and those with low tolerance in the cerebral cortex . - pubmed
During adaptation to hypoxia animals with high and low tolerance had varying changes in acid - base balance . - pubmed
The data obtained allow the conclusion that there is a correlation between the rate of brain tissue metabolism , acid - base balance of jugular vein blood and individual animals ' tolerance to hypoxia . - pubmed
Distribution of calcium and magnesium in rat kidney homogenate fractions accompanying magnesium deficiency induced nephrocalcinosis . - pubmed
Comparative evaluation of potato diploids , tetraploids , and chimerae periclinal with respect to ploidy . - pubmed
[ Induction of gastrointestinal hemorrhages in the rat by acetylsalicylic acid and acetylsalicylic acid - containing drugs ] . - pubmed
Fluorouracil : mechanism of action in human skin and actinic keratoses . - pubmed
Plasma tocopherol concentrations and vitamin E deficiency in dogs . - pubmed
Two groups of patients with transient ischaemic attack and minor stroke without detectable haemodynamic stenotic lesions were evaluated by neuropsychological tests and compared with a control group . - pubmed
The mean values of the scores adjusted for age and educational background demonstrated that the patients with transient ischaemic attack did not have a worse performance than normal subjects in any of the tests , the patients with minor stroke had a worse performance than normals , particularly in Rey 's figure - copying test ( P less than 0.025 ) , and the latter test was not affected by educational background or age of the subjects . - pubmed
We analyzed mononuclear leukocytes from patients with various human leukemias by high - resolution two - dimensional electrophoresis . - pubmed
Postmortem studies of six patients , four with documented optic nerve lesions , are presented . - pubmed
After intrapleural instillation of talc for sclerosis of malignant pleural effusions , dyspnea occurred in three patients , progressed gradually over 72 hours , and culminated in acute respiratory failure characterized by bilateral diffuse pulmonary infiltrates with normal pulmonary artery occlusion pressures . - pubmed
When talc is used in patients who are unresponsive to tetracycline , we suggest clinical monitoring for respiratory compromise for 72 hours after the procedure . - pubmed
Infection was verified in 23 patients ( mean gestational age 32 weeks and mean body weight 2100 g ) and clinical cure or marked improvement occurred in 20 of these . - pubmed
Of the remaining 3 patients , 2 died , partly due to reasons unassociated with infection . - pubmed
Fifty - one patients with metastatic breast cancer were randomly allocated to receive either a four drug combination consisting of cyclophosphamide , methotrexate , 5 - fluorouracil , and prednisone ( CMFP ) , or a combination of vincristine , Adriamycin , and cyclophosphamide ( VAC ) with cross - over on relapse . - pubmed
1 The blood pressure lowering effect of xipamide , a non - thiazide diuretic given for 6 weeks was compared in a randomised cross - over trial with that of cyclopenthiazide in 14 patients with essential hypertension . - pubmed
4 These results suggest that 10 mg or 20 mg of xipamide daily is effective in lowering blood pressure in hypertensive patients but is associated with hypokalaemia . - pubmed
In view of recent evidence linking diuretic - induced hypokalaemia with cardiac dysrhythmias in patients with essential hypertension we would suggest that thiazide diuretics be used in preference to xipamide for the routine management of essential hypertension . - pubmed
Twelve patients were followed up 6 - 40 months after implantation of a velours prosthesis due to trauma involving the clavicle . - pubmed
On the X - rays of the ten patients with a coracoclavicular loop there was a marked bone erosion in the area where the graft crossed the clavicle , and three patients had clinical symptoms as well . - pubmed
Adults developed various tachycardias ( tachyarrhythmias ) compared to severe sinus bradycardias in the newborns . - pubmed
In conclusion , the newborn rat is much more sensitive to digoxin toxicity than the adult as demonstrated by ECG criteria . - pubmed
Several individuals possessing the variant exhibited mild anemia . - pubmed
Effect of vitamin B6 deficiency on in vitro uptake and metabolism of pyridoxine x HCL by rat jejunum . - pubmed
METHODS : Sprague - Dawley rats developed cirrhosis with ascites approximately 20 weeks after weekly intragastric instillation of carbon tetrachloride . - pubmed
OBJECTIVE : To assess the development and cause of malabsorption in rhesus macaques following experimental simian immunodeficiency virus ( SIV ) infection and to evaluate its impact on nutritional status . - pubmed
DESIGN : Clinical malabsorption tests and serial jejunal aspirates and biopsies were obtained from nine SIV - infected and three uninfected animals prior to infection and at 1 , 2 , 4 , 8 , 12 , 24 , 40 and 52 weeks postinoculation . - pubmed
Bacterial overgrowth was not considered to be a cause of malabsorption . - pubmed
The high proportion of macaques experiencing malabsorption without detectable pathogens , suggests an enteropathogenic role for SIV . - pubmed
Renal cell carcinoma in children : a single institution 's experience . - pubmed
Seven patients with renal cell carcinomas ( RCC ) were treated at the Department of Pediatric Oncology in Prague over a period of 15 years . - pubmed
Four patients are without evidence of disease with a minimal follow - up period of 2 years . - pubmed
One patient died of tumor emboli to the lungs at operation . - pubmed
Tumor diagnosis and treatment of the patients in the lower clinical stages seem to have a favorable prognostic impact in childhood RCC . - pubmed
We have recently shown that brain temperature can drop even though rectal and skull readings are maintained near 37 degrees C during global forebrain ischemia in the gerbil . - pubmed
In this study gerbils were subjected to 5 min of ischemia followed by 85 min of extended halothane anesthesia , while rectal and skull temperatures were kept at normal values . - pubmed
Ictal SPECT provides unique information for the clinician treating patients with refractory epilepsy and reveals insights into the pathophysiology of seizures . - pubmed
We have devised and implemented techniques for rapid reconstitution of 99mTc - HMPAO adjacent to the video - EEG monitoring suite such that the tracer can be rapidly injected into patients when spontaneous seizures occur . - pubmed
The clinical results in patients with temporal lobe epilepsy show that ictal injections ( 97 % correct lateralization of focus , 0 % incorrect ) are more sensitive and accurate compared to interictal studies ( 48 % correct , 10 % incorrect ) , demonstrating that the implementation of these techniques is worthwhile . - pubmed
RESULTS : Thirteen women and 6 men in this incidence cohort of PMR had & gt ; or = 1 episode of distal extremity swelling with pitting edema . - pubmed
Giant cell arteritis was also identified in 5 patients . - pubmed
In 11 patients , the swelling and edema development concurrently with proximal PMR symptoms . - pubmed
In 2 patients , the distal swelling was the initial manifestation , and in 6 patients , the distal symptoms developed during relapses or recurrences of PMR . - pubmed
Audiogenic seizures following global ischemia induced by chest compression in Long - Evans rats . - pubmed
Transient global ischemia was used to produce a rat model of generalized tonic - clonic epilepsy . - pubmed
Controlled chest compression in ketamine - anesthesized Long - Evans rats produced transient global ischemia by mechanically preventing the heart from pumping blood . - pubmed
With a temporal muscle ( skull ) temperature of 35 + /- 0.4 degrees C , 75 % ( 76/102 ) of the rats survived 7 min of chest compression . - pubmed
Generalized seizures could be evoked in 78 % ( 59/76 ) of the surviving rats by a 60 s exposure to a loud sound ( bell , 110 dB ) beginning 24 h after the ischemic episode . - pubmed
The seizure patterns seen resembled those described by Maresceaux ( 1987 ) for genetically seizure - prone Wistar rats . - pubmed
Susceptibility to sound - induced seizures declined with time , with wide variations in recovery rate between individuals ; one rat showed a daily sound - induced seizure for over 5 months . - pubmed
Mometasone furoate aqueous nasal spray ( Nasonex ) was compared with beclomethasone dipropionate ( BDP ) aqueous nasal spray in a double - blind , randomized , placebo - controlled , double - dummy , parallel - group study of adults with moderate to severe seasonal allergic rhinitis . - pubmed
Patients allergic to at least one tree and/or grass aeroallergen received one of the following regimens for up to 4 weeks ; mometasone furoate 100 micrograms once daily [ OD ] ( n = 126 ) or 200 micrograms OD ( n = 126 ) , BDP 200 micrograms twice daily ( n = 126 ) , or only placebo spray ( n = 123 ) . - pubmed
Stimulation of neonatal mouse calvarial bone resorption by the glucocorticoids hydrocortisone and dexamethasone . - pubmed
We developed a novel and efficient cDNA subtraction method to isolate rat hepatocellular carcinoma ( HCC)-related genes . - pubmed
The SPs were found both in the hippocampus and frontal cortex while NFTs were seen only in the hippocampus in non - demented aged individuals . - pubmed
The combination of genotypic analysis and new treatment methods offers exciting new prospects in the management of patients with cutaneous lymphoma . - pubmed
Such strains were selected from 344 human rotavirus strains recovered in palermo during those years after characterization by electropherotyping , subgrouping and G serotyping . - pubmed
RESULTS : The modified CRM was used in two dose - finding trials of 9 - aminocamptothecin in patients with newly diagnosed and recurrent glioblastoma who were taking anticonvulsant medication . - pubmed
Influence of computed tomography on pretherapeutic tumor staging in head and neck cancer patients . - pubmed
Refinements in radiographic techniques have resulted in increased use of radiographic studies in the evaluation of patients with head and neck cancer over the past 20 years . - pubmed
In colony formation assays against the human head and neck squamous carcinoma cell line SCC25 after 72 h of treatment , the 5 - and 8 - deaza analogues were approximately as potent as 3 , whereas the 5,8 - dideaza analogue was 3 times more potent . - pubmed
The 5 - methyl-5 - deaza analogue of 3 was also tested at the National Cancer Institute against a panel of 50 human tumor cell lines in culture and was consistently more potent than 3 , with IC50 values in the low - nanomolar to subnanomolar range against most of the tumors . - pubmed
Its differential expression has been documented in various human tumours . - pubmed
h-1 , respectively ; n=30 ) , type IIa hyperlipidemic patients ( 4 . - pubmed
h-1 , respectively ; n=36 ) , and type IIb hyperlipidemic patients ( 3.90+/-0.79 mg / L and 575+/-48 nmol . - pubmed
PATIENTS : Infertile women with different stages of endometriosis who were treated by laparoscopic surgery , with a mean duration of infertility of 80.7 ( + /-50 [ SD ] ) months . - pubmed
INTERVENTIONS : Patients were treated by cauterization of the foci , adhesiolysis , endometrioma stripping , and distal tubal reconstruction according to their lesions . - pubmed
MAIN OUTCOME MEASURE : Cumulative pregnancy rate of infertile women after laparoscopic treatment of endometriosis with or without ovulation induction . - pubmed
In the present study HD-03 , a herbal formulation was investigated for its anti - cholestatic activity in TAA - induced cholestasis in anaesthetized guinea pigs . - pubmed
We investigated 1 , 042 consecutive patients who had first strokes , during a period of 5 years ( from June 1992 to May 1997 ) and classified them prospectively based on etiopathogenic mechanisms . - pubmed
Patients with transient ischemic attacks and subarachnoid hemorrhage were excluded . - pubmed
Forty - six percent of the patients arrived within 3 h from stroke onset . - pubmed
Study of acute chagasic mice under immunosuppressive therapy by cyclosporin A : modulation and confocal analysis of inflammatory reaction . - pubmed
The in vivo effects of cyclosporin A ( CsA ) on Trypanosoma cruzi infection were examined using different schedules of the drug in mice infected with the Y strain . - pubmed
Parasitaemia at day 8 after infection among CsA - treated animals was usually higher than control infected non - treated mice . - pubmed
The mean time of death in the animals treated with 200 mg / kg 5 days after infection and in infected non - treated control mice were respectively 29.0 and 22.6 days . - pubmed
The kinetics analysis of the leukocyte population of animals treated with a single dose of 200 mg / kg of CsA before or after infection did not show the alternate pattern of leukopenia / leukocytosis observed in control groups of infected mice but differential cell counts indicated a modulatory action upon circulating leukocytes of therapeutic doses of CsA. - pubmed
METHODS : We compared cardiothoracic ratio ( CTR ) , left ventricular ejection fraction ( LVEF ) from radionuclide ventriculography , and left ventricular dimensions from echocardiography in a population of 91 patients ( aged 60.4 ( SD 9.6 ) years ) with a diagnosis of chronic heart failure . - pubmed
We have observed 2 cases of eczema herpeticum among 36 patients with atopic dermatitis treated with a topical preparation containing 0.1 % tacrolimus . - pubmed
The lesions resolved quickly under intravenous acyclovir treatment but resulted in important facial scarring in the male patient . - pubmed
Depression in stroke patients 7 years following stroke . - pubmed
OBJECTIVE : To study the frequency of depression in stroke patients many years following stroke , most previous studies having concentrated on the first few years . - pubmed
METHOD : Participants of a previous study of post - stroke depression ( 99 stroke patients and 28 control subjects ) were re - examined 7 years later . - pubmed
RESULTS : Twenty per cent of the stroke patients fulfilled the criteria for major or minor depression compared with 11 % of the control subjects . - pubmed
No differences in cognitive function were found between depressed and non - depressed stroke patients . - pubmed
The stroke patients reported experiencing more lability of mood and irritability during the 7 - year period following stroke than the control subjects . - pubmed
Depressed stroke patients experienced more impairment of concentration and memory function than non - depressed stroke patients . - pubmed
CONCLUSION : Affective symptoms are common among stroke patients 7 years following stroke . - pubmed
Although the findings are similar , a postpartum uterus , lymphoma , and a bleeding uterus caused pelvic FDG uptake in these patients . - pubmed
Interestingly , of these three patients , the patient with lymphoma had the lowest level of FDG uptake . - pubmed
Oral desloratadine 5 mg once daily for up to 4 weeks in patients with seasonal allergic rhinitis ( SAR ) significantly reduced nasal ( including congestion ) and non - nasal symptoms and improved health - related quality of life compared with placebo . - pubmed
Desloratadine 5 mg once daily for 6 weeks significantly improved pruritus and reduced the number of hives compared with placebo in patients with chronic idiopathic urticaria ( CIU ) . - pubmed
Desloratadine was well tolerated in clinical trials and had an adverse event profile similar to that of placebo in patients with SAR ( with or without asthma ) or CIU . - pubmed
In a case - vignette , the condition of an 82 - year - old man with acute gastrointestinal bleeding is described comprehensively in combination with 3 different levels of information about the patient wishes ( no information , DNR order , advance directive ) . - pubmed
OBJECTIVE : To examine functional improvement patterns of persons with stroke , traumatic brain injury ( TBI ) , and spinal cord injury ( SCI ) . - pubmed
RESULTS : With the exception of cognitive functioning for persons with SCI , LOS was related to initial functional status , with patients with greater disability having longer LOS ( eg , initial motor status for persons with stroke was 48.3 for those with a 2 - week stay , 36.8 for a 6 - week stay , with the averages between decreasing monotonically ) . - pubmed
In 16 patients with ARDS submitted to mechanical ventilation in volume - controlled mode with a supportive respiratory rate of 15 breaths / minute , we constructed the static PV curve on the first day of respiratory support and determined the intrinsic positive end - expiratory pressure ( PEEPi4 ) during a prolonged end - expiratory pause ( 4 seconds ) . - pubmed
Between July 1994 and July 2001 , all patients with superficial transitional cell carcinoma ( TCC ) of urinary bladder ( pT1 and pTa ) , 7 days after undergoing transurethral resection of tumor were subjected to intravesical instillation of 60 mg BCG ( Danish 1331 ) combined with 5 million IU interferon alpha-2b ( Intron - A ) mixed with 50 ml of physiological saline weekly for 8 weeks , then fortnightly for 8 weeks , then monthly for 8 weeks , followed by maintenance dose at the end of the 9th , 12th , 18th , 24th months . - pubmed
At the end of the 1st year of follow - up 84 % of patients had no tumor recurrence which dropped to 36 % at the end of 5 - year follow - up , while no incidence of disease progression at the end of the first year was recorded but was 20 % at the end of 5 years , thereby resulting in a disease progression - free 5 - year interval in 80 % of our patients . - pubmed
The epidemiology of invasive Streptococcus agalactiae ( GBS ) disease was evaluated in South African children . - pubmed
Shunt infection may be the cause in patients with ventriculoperitoneal shunt , who have acute abdomen . - pubmed
[ Causative factors in development of breast carcinoma in mice ] . - pubmed
Rat behavior in two models of anxiety and brain [ 3H]muscimol binding : pharmacological , correlation , and multifactor analysis . - pubmed
The contribution of GABAergic mechanisms to rat emotional behavior in two animal models of anxiety ( open field test of neophobia and aversively conditioned freezing reaction ) , was confirmed by pharmacological analysis , using anxiolytic ( midazolam ) and anxiogenic ( picrotoxin ) compounds . - pubmed
The metabolism of phenylalanine and tyrosine in mutant strains of Escherichia coli . - pubmed
Case 1 was a 44 - year - old man with T1N2M0 adenocarcinoma . - pubmed
Case 2 was a 67 - year - old man with T4N1M0 squamous cell carcinoma . - pubmed
Case 3 was a 72 - year - old man with T4N2M0 squamous cell carcinoma . - pubmed
Patients with vagal paragangliomas typically present with an asymptomatic neck mass and , less frequently , with cranial neuropathies . - pubmed
Stratified by treatment group , the 3 - year incidence of CIN was 0/23 ( 0 % ) in prednisone treated patients , 0/4 ( 0 % ) in AZA treated patients , 2/8 ( 25 % ) in IVCYC treated patients , and 4/26 ( 15 % ) in CYC + AZA + prednisone treated patients . - pubmed
Cardiovascular manifestations of beriberi based on a study of ten patients . - pubmed
The discovery of lithium 's efficacy as a mood - stabilizing agent revolutionized the treatment of patients with bipolar disorder and after 5 decades this drug continues to be the mainstay of treatment of this disorder . - pubmed
Antidepressant effects of different schedules of repetitive transcranial magnetic stimulation vs. clomipramine in patients with major depression : relationship to changes in cortical excitability . - pubmed
The aim of the present study was to compare efficacy of rTMS in various configurations and clomipramine treatment in patients with major depression ( MD ) and to evaluate the relationship between clinical outcome and changes in cortical excitability . - pubmed
Fifty - nine MD patients were randomized to receive ( 1 ) left ( n = 12 ) or right ( n = 12 ) 3 Hz rTMS with placebo medication ; ( 2 ) left ( n = 10 ) or right ( n = 9 ) 10 Hz rTMS with placebo medication ; ( 3 ) active medication ( clomipramine ) with sham rTMS ( n = 16 ) . - pubmed
Our results suggest that 3 Hz left rTMS has a higher therapeutic efficacy and tolerability in patients with MD . - pubmed
Subcortical white matter metabolic changes remote from focal hemorrhagic lesions suggest diffuse injury after human traumatic brain injury . - pubmed
METHODS : Sixteen normal volunteers and 10 TBI patients ( Glasgow Coma Scale score , 4 - 10 ; age , 17 - 64 yr ; 6 with focal and 4 with diffuse injury ) were studied . - pubmed
Vulvar lipoleiomyoma in a dog . - pubmed
A vulvar neoplasm from a 5 - year - old female Siberian Husky dog was removed surgically and examined histologically . - pubmed
This is , to the author 's knowledge , the first report of canine vulvar lipoleiomyoma . - pubmed
METHODS : The study involved 188 subjects , 101 hypertensives and 87 normotensives . - pubmed
The diagnosis of two patients with the infantile form of GM1 gangliosidosis and 11 carriers in a small mountainous village in Cyprus prompted us to carry out a study in order to establish the frequency of carriers in the village and identify the mutations involved . - pubmed
Non - REM - sleep instability in recurrent sleepwalking in pre - pubertal children . - pubmed
BACKGROUND AND PURPOSE : We questioned whether or not the sleep of pre - pubertal children with recurrent sleepwalking was different from that recorded in normal children . - pubmed
However , the utility of PET / CT in patients with both cancer and osteoporosis is less well delineated . - pubmed
In this case , a patient with known metastatic colorectal cancer who was investigated by many forms of conventional imaging for back and pelvic pain was found to have osteoporotic fractures using PET / CT . - pubmed
OBJECTIVE : To determine the complication and hospitalization rates in children with cystic fibrosis ( CF ) by mode of diagnosis . - pubmed
Complications were defined for the calendar year of diagnosis as stunting ( length & lt;3rd percentile ) , wasting ( weight & lt;3rd percentile ) , positive Pseudomonas aeruginosa culture results , and hypoelectrolytemia or edema and hypoproteinemia . - pubmed
Subsequent molecular genetic studies revealed that a hydatid cyst from the plateau pika , Ochotona curzoniae , had unique mitochondrial DNA sequences which are dissimilar to any published sequences of Echinococcus . - pubmed
shiquicus has been found at other areas surveyed on the plateau ; however , no infections in humans caused by E. - pubmed
( iv ) For patients with non - thymomatous autoimmune MG , thymectomy ( TE ) is recommended as an option to increase the probability of remission or improvement ( level B recommendation ) . - pubmed
( ix ) All neuromyotonia patients should be treated symptomatically with an anti - epileptic drug that reduces peripheral nerve hyperexcitability ( good practice point ) . - pubmed
The effect of heat shock on paclitaxel production in Taxus yunnanensis cell suspension cultures : role of abscisic acid pretreatment . - pubmed
The heat shock ( HS ) response is a conserved cellular defense mechanism to elevated temperatures , observed in cells from bacteria to human . - pubmed
Seroprevalence of herpes simplex virus types 1 and 2 , Epstein - Barr virus , and cytomegalovirus in children with acute lymphoblastic leukemia in Egypt . - pubmed
This study aimed at studying seroprevalence of 3 herpes viruses Herpes simplex virus types 1 and 2 ( HSV 1 and 2 ) , Epstein - Barr virus ( EBV ) , and cytomegalovirus ( CMV ) in children with acute lymphoblastic leukemia ( ALL ) . - pubmed
METHODS : We conducted this study on 68 newly diagnosed pediatric patients with ALL presented to the Pediatric Oncology Service of National Cancer Institute , Cairo University , Egypt from November 2001 to June 2003 . - pubmed
CONCLUSION : The data show a higher exposure to HSV-1 and 2 both primary infections and reactivation among ALL children . - pubmed
Therefore , acyclovir prophylaxis could be highly effective for seropositive leukemic patients who are undergoing induction chemotherapy . - pubmed
Speech characteristics of patients with pallido - ponto - nigral degeneration and their application to presymptomatic detection in at - risk relatives . - pubmed
PURPOSE : This report describes the speech characteristics of individuals with a neurodegenerative syndrome called pallido - ponto - nigral degeneration ( PPND ) and examines the speech samples of at - risk , but asymptomatic , relatives for possible preclinical detection . - pubmed
METHODS : Study population comprising 143 outpatients with clinical diagnosis of probable AD ( 73.3 + /- 7.0 years ) were classified into 2 groups according to the presence or absence of SBIs on magnetic resonance imaging . - pubmed
RESULTS : SBIs were noted in 32.9 % ( 47/143 ) of the AD patients . - pubmed
Amnionitis with Ureaplasma urealyticum or other microbes leads to increased morbidity and prolonged hospitalization in very low birth weight infants . - pubmed
Children of mothers with positive amniotic fluid cultures had significantly lower gestational ages ( 26 + 4 weeks for Ureaplasma urealyticum [ p=0.04 ] and 25 + 5 weeks for other microorganisms [ p=0.0017 ] versus 28 + 6 weeks for mothers with negative amniotic fluid cultures ) and lower birth weights ( 975 g [ n.s . ] - pubmed
In none of the patients treated with macrolids for proven Ureaplasma urealyticum amnionitis could the microbes be eradicated . - pubmed
Twenty patients with moderate to severe COPD [ 12 women , 66 + /- 9.4 years of age and forced expiratory volume in 1 second ( FEV(1 ) ) of 32 % + /- 12 % of predicted value ] and 20 healthy age- , gender- , and body mass index ( BMI)-matched controls ( 10 nonsymptomatic smokers and 10 nonsmokers ) were included in the study . - pubmed
In the present study , bipolar I patients were assessed at index hospitalization using standardized symptom measures and followed up to 28 months . - pubmed
METHODS : This project was a prospective study of a convenience sample of 304 ED patients undergoing ECG analysis during their evaluation in the ED of a level 1 trauma center . - pubmed
During the past decade , the involvement of different cell types in CHS has been investigated by the use of antibody - induced depletion of specific subtypes of immunological cells and by studying knockout mice lacking one or more of these immunological cell populations . - pubmed
OBJECTIVES : To develop a method for studying the collective cellular dynamics of immune cells in the draining lymph nodes during CHS in intact animals . - pubmed
Evaluation of the available anti - HCV antibody detection tests and RT - PCR assay in the diagnosis of hepatitis C virus infection . - pubmed
The study included 316 serum samples from three groups : blood donors , patients on maintenance hemodialysis ( HD ) and patients infected with the human immunodeficiency virus ( HIV ) . - pubmed
For patients on HD and those positive for HIV , the test positivity was respectively 59.3 % and 5.3 % by ELISA , 64 % and 10.5 % by RIBA and , 66.3 % and 21 % by PCR test . - pubmed
The percentage of false negativity of HCV - Ab by ELISA and RIBA when compared with RT - PCR test was 3.5 and 8.1 % for samples blood donors , 17.1 and 25.7 % for HD patients and 5.6 and 16.7 % for HIV - infected samples , respectively . - pubmed
The false positivity of HCV - Ab by ELISA and RIBA , when compared with RT - PCR , was 5 % , 3.9 % and zero for blood donors , HD patients and HIV - HCV co - infected cases , respectively . - pubmed
Thus , it is very important to screen blood donors , HD patients and HIV - infected patients by using the RT - PCR for HCV - RNA to avoid false negative results . - pubmed
[ A case of complete remission(CR)persisting from UFT - E in an old patient with liver metastasis of gastric cancer ] . - pubmed
A 82 - year - old woman with gastric cancer underwent distal gastrectomy with level 2 lymph node dissection(M , Less , 2.2 x 2.0 cm , type 1 , fH0 , fP0 , fM0 , fT2 , fN2(+ ) , por 1 , med , INF beta , ly2 , v2 , fPM(- ) , fDM(- ) , fStage IIIa ) . - pubmed
Locomotor activity is a predictive test after global ischemia - reperfusion in Mongolian gerbils . - pubmed
OBJECTIVE : The Mongolian gerbil is one of the main animal species used for the study of global ischemia , due to its specific Circle of Willis . - pubmed
The locomotor activity of the animals was also examined in an open field at 24 hours and seven days after ischemia . - pubmed
CONCLUSIONS : Locomotor activity in an open field is a useful reference as a predictive test to determine the sensitivity of experimental animals to ischemia . - pubmed
One patient had a combination of acquired coarctation and false aneurysm . - pubmed
CONCLUSION : Covered stent implantation for treatment of aortic coarctation is safe and highly effective in selected patients . - pubmed
infestation and suspected demodicosis of alpacas ( Vicugna pacos ) in New Zealand . - pubmed
Rate of weight loss and mortality , of the Nigerian periwinkle , Tympanotonus fuscatus var . - pubmed
EXPERIMENTAL APPROACH : O ( 2 )(- ) was generated in primary cultures of angiotensin II - stimulated preglomerular vascular smooth muscle cells from spontaneously hypertensive rats and detected by lucigenin - enhanced chemiluminescence . - pubmed
A 66 - year - old man developed tension pneumocephalus after failed lumbar drainage before clipping surgery for a ruptured anterior communicating artery aneurysm . - pubmed
The patient 's neurological status deteriorated suddenly into coma within 15 hours after uneventful clipping of the aneurysm . - pubmed
Urinary 6 - sulfatoxymelatonin level in age - related macular degeneration patients . - pubmed
The purpose of this study was to investigate melatonin levels in age - related macular degeneration ( AMD ) patients by measurement of 6 - sulfatoxymelatonin levels ( aMT6s ) , the major metabolite of melatonin in urine , and compare it with a group of age- and gender - matched controls . - pubmed
METHODS : The first urine of the morning was collected from 43 AMD patients and 12 controls who did not have AMD . - pubmed
After adjustment for various factors ( age , smoking , cancer , and coronary heart disease ) that may influence the aMT6s level , the odds - ratio of urinary aMT6s comparing AMD patients to controls was 0.65 ( 95 % confidence interval=0.48 - 0.88 , p=0.0036 ) , indicating that urinary aMT6s level in AMD patients was lower than in controls even after multivariate adjustment . - pubmed
CONCLUSIONS : Urinary aMT6s level in AMD patients was 40 % lower than in age- and gender - matched controls . - pubmed
This difference between AMD patients and controls is present after adjustment for the factors of age , smoking , and histories of cancer and coronary heart disease . - pubmed
Excessive thyroid hormone induces cardiac hypertrophy and promotes heart failure in patients with hyperthyroidism , but the mechanism remains elusive . - pubmed
Rats were orally administered with levothyroxine ( 100 microg / kg , T(4 ) ) for 4 weeks to induce hyperthyroidism . - pubmed
The calculated stroke volume decreased and the shortening amplitude - frequency relationship in unloaded contraction of isolated cardiomyocytes was negative in T(4)-treated rats . - pubmed
RECENT FINDINGS : The development of molecular diagnostics has markedly improved the ability to rapidly identify infections in transplantation patients and has improved clinical care . - pubmed
Monitoring for cytomegalovirus and Epstein - Barr virus by PCR offers the opportunity for preemptive interventions . - pubmed
Concomitant administration of nitric oxide and glucocorticoids improves protection against bronchoconstriction in a murine model of asthma . - pubmed
The cytotoxicity data suggest that these compounds may be endowed with important antitumor properties , especially H(3)L(1 ) and [ Pt ( mu - H ( 3 ) L ( 2 ))]( 2 ) since they not only circumvent cisplatin resistance in A2780cisR cells but also exhibit high antiproliferative activity in human non - small cell lung cancer NCI - H460 cells . - pubmed
Mice received diets enriched in methionine with low or high levels of folate , B ( 12 ) and B ( 6 ) ( diets B and C , respectively ) , and diet only with low levels of folate , B ( 12 ) and B ( 6 ) ( diets D ) , to induce mild HHcy . - pubmed
Normal mice fed on diets B , C and D presented mild HHcy , but they did not develop atherosclerotic lesions after 24 weeks of diet . - pubmed
Awareness and filling - in of the human blind spot : linking psychophysics with retinal topography . - pubmed
Owing to meiotic irregularities of triticale hybrids , aneuploidy may affect the efficiency of androgenesis more severely than in meiotically stable crops . - pubmed
This study addresses the issue of aneuploidy among androgenic regenerants of triticale . - pubmed
Rye chromosomes involved in aneuploidy greatly outnumbered wheat chromosomes ; in C(0 ) rye chromosomes 2R and 5R were most frequently involved . - pubmed
[ Protective effect of limb ischemic preconditioning against liver ischemia / reperfusion injury in the rat ] . - pubmed
OBJECTIVE : To study the protective effect of limb ischemic preconditioning against liver ischemia / reperfusion injury in the rat . - pubmed
METHODS : Rats were randomly divided into four groups ( n = 8) : ( 1 ) Sham group ( S group ) , rats without ischemic preconditioning ( IPC ) , ( 2 ) Ischemia / reperfusion ( I / R ) without IP ( I / R group ) ; ( 3 ) Rats with 5 min IPC ( IPC group ) ; ( 4 ) Rats with lower limbs IPC and repeated three times ( remote ischemic preconditioning , RPC group ) ; The rats were subjected to 60 - min sustained liver ischemia followed by 180 - min reperfusion except S group . - pubmed
All ischemia rats were only subjected to 70 % liver ischemia . - pubmed
CONCLUSION : The limb ischemic preconditioning has a protective effects against liver ischemia / reperfusion injury in the rat , possibly are due to suppression of liver inflammatory reaction , improvement of liver microcirculation . - pubmed
Pressure ulcers are one of the most common complications in elderly , incontinent or paralyzed patients . - pubmed
Lipopolysaccharide ( LPS ) , d - galactosamine ( GalN)-induced FHF is a well - established model of liver injury in mice . - pubmed
RESULTS : After the induction of FHF , all control mice died within 12 hr of GalN / LPS administration . - pubmed
Palliative care for patients with Huntington ' s disease # 201 . - pubmed
The subarachnoid infusion of narcotics by programmable devices in patients with chronic non - malignant pain can be a useful therapeutic method . - pubmed
We present a case report of a woman with both chronic perineal pain and sciatic pain with radiation to her lower limbs caused by failed back surgery syndrome . - pubmed
After surgical implantation of a programmable infusion pump , the patient 's leg pain improved with an intrathecal infusion of morphine and bupivacaine . - pubmed
In all patients , laparoscopy was considered to be contraindicated due to extensive pelvic adhesions . - pubmed
After 45 embryo transfer procedures in 19 patients , 18 pregnancies with 12 live births , 6 miscarriages and 1 immature delivery ( probably related to cervical insufficiency leading to chorioamnionitis and subsequent rupture of the membranes ) were observed . - pubmed
CONCLUSION(S ): Essure ( ) devices are effective in inducing proximal tubal occlusion in subfertile patients with hydrosalpinges . - pubmed
OBJECTIVE : To evaluate the efficacy of endometrial biopsy followed by intrauterine system - releasing levonorgestrel ( LNG - IUS ) insertion in the treatment of women with menorrhagia . - pubmed
Ninety - two patients who had menorrhagia due to non - malignant causes were sequentially recruited into the study over a 3 - year period ( age range 29 - 51 years ) . - pubmed
Because airway management is often complicated in trauma patients , alternative devices need to be available preclinical and a fiber - optic endoscope should be available within the hospital . - pubmed
Recently , an animal model of combined fatigue was designed by housing rats in a cage filled with water . - pubmed
Rats were housed for 5 d under water - immersed conditions , and the extent of fatigue was evaluated by a weight - loaded forced swimming test . - pubmed
The past decade of investigation into the pharmacologic treatment of hypertension in children has been rewarding . - pubmed
The studies have shown that blood pressure medications effectively reduce blood pressure in children with hypertension and that these agents are generally well tolerated with few treatment - related adverse effects . - pubmed
RESULT : Medicinal tween 80 and injectable tween 80 with 5 % concentration caused obvious vascular hyper permeability in ICR mice , but the degree of vascular hyperpermeability caused by injectable tween 80 was lighter than by medicinal tween 80 . - pubmed
Streptococcus pneumoniae is an aerotolerant gram - positive bacterium that causes an array of diseases , including pneumonia , otitis media , and meningitis . - pubmed
Eleven patients with idiopathic Parkinson ' s disease consented to participate in neuronal recordings during stimulator implantation surgery . - pubmed
Sleep apnoea and the potential benefits of a good night 's sleep in patients receiving maintenance dialysis . - pubmed
The study population consisted of 116 patients with PCAD , and 119 controls . - pubmed
OBJECTIVE : To determine the clinical effect , treatment times , and rheoencephalogram changes in vertebral artery type cervical spondylosis patients treated with innovative Tuina manipulations . - pubmed
METHODS : One hundred and twenty six cervical spondylosis patients ( vertebral artery type ) were randomly divided into test and control groups . - pubmed
CONCLUSION : Both innovative Tuina manipulations and routine Tuina manipulations produced satisfactory therapeutic results in vertebral artery type cervical spondylosis patients . - pubmed
Biweekly Docetaxel and S-1 combination chemotherapy as first - line treatment for elderly patients with advanced gastric cancer . - pubmed
BACKGROUND : This study evaluated the clinicopathological features and survival rates of patients with inflammatory bowel disease who developed colorectal cancer ( CRC ) . - pubmed
We agree with the approach to management of RCDI that has been proposed in several articles , that is , on confirmation of a first recurrence of CDI by a stool toxin assay and clinical symptoms , a 14 - day course of metronidazole or vancomycin ; for a second recurrence , a tapered - pulsed course of vancomycin ; and , for 3 or more recurrences , a repeat course of the tapered - pulsed vancomycin and adjunctive Saccharomyces boulardii or cholestyramine . - pubmed
Hypothesis - based weight - of - evidence evaluation of the human carcinogenicity of toluene diisocyanate . - pubmed
It is classified as a possible human carcinogen , based primarily on increased tumor incidences in rodents treated with TDI by oral gavage . - pubmed
The experimental animal studies indicate that inhalation exposure to TDI does not induce tumors in rats or mice . - pubmed
Tumors observed after oral gavage exposure are most likely due to the conversion of approximately 5 % of the administered TDI to toluene diamine ( TDA ) , a known rodent tumorigen . - pubmed
This contention is supported by the observations that TDA is rapidly formed from TDI during in vitro genotoxicity assays , the spectra of responses to TDA and TDI in these assays and in oral bioassays are essentially the same , and TDI is not genotoxic in rodents or humans in vivo after inhalation exposure , when TDA is not formed to a biologically significant degree . - pubmed
The primary objective of this 96 - week open - label , noncomparative , multicenter Phase 3b study ( NCT00478231 ) was to assess the safety of maraviroc in combination with optimized background therapy ( OBT ) , which could include recently introduced agents such as darunavir and raltegravir in TE patients in Brazil with R5 HIV-1 and limited therapeutic options . - pubmed
Lung volume recruitment involves deep inflation techniques to achieve maximum insufflation capacity in patients with respiratory muscle weakness , in order to increase peak cough flow , thus helping to maintain airway patency and improve ventilation . - pubmed
METHODS : Thirty eight ( 38 ) FXTAS patients and 10 age - matched normal controls underwent a detailed neurological examination that included all but one item ( i.e. - pubmed
RESULTS : The FXTAS patient group displayed substantially higher prevalence of parkinsonian features including body bradykinesia ( 57 % ) and rest tremor ( 26 % ) , compared to the control group . - pubmed
Furthermore , parkinsonism was identified in 29 % of FXTAS patients . - pubmed
METHODS : A sample of subjects with a parkinsonian disorder was evaluated . - pubmed
RESULTS : A total of 32 subjects with atypical parkinsonism and 54 subjects with Parkinson ' s disease were included . - pubmed
METHODS : We conducted a prospective study of 120 consecutive patients admitted for acute myocardial infarction , from April 2011 to March 2012 . - pubmed
All patients have undergone an overnight sleep study using a portable diagnostic device , in the 15 days following the acute coronary syndrome . - pubmed
Smoking was the major cardiovascular risk factor with 72 % of all patients ; prevalence of diabetes was 40 % and hypertension was found in 44 % of the population . - pubmed
Severe OSA was diagnosed in 16 % of all patients and mean AHI was 15.76 + - 14.93 . - pubmed
Mean ESS was 2.2 + - 1.84 in the global population while it was 5.2 + - 1.2 in patients with severe OSAS . - pubmed
CONCLUSION : The prevalence of OSA in patients with acute myocardial infarction was very high . - pubmed
BACKGROUND : Despite the fact that the number of disabled individuals participating in sports is increasing , there are only sparse reports in the literature concerning overuse injuries . - pubmed
Data were collected using semi - structured pretested Amharic version questionnaire by interviewing index children 's mothers / caretakers , copying from vaccine card and observing BCG vaccine scar . - pubmed
We found that the proportion of MAIT cell in blood and colon of HIV+ patients are reduced in untreated infection . - pubmed
Infection of the optic apparatus and hypothalamus by Mycobacterium haemophilum . - pubmed
Impaired leptomeningeal collateral flow contributes to the poor outcome following experimental stroke in the Type 2 diabetic mice . - pubmed
Using Doppler optical coherent tomography , a robust recruitment of leptomeningeal collateral flow was detected immediately after middle cerebral artery ( MCA ) occlusion in C57BL/6 mice , and it continued to grow over the course of 1 week . - pubmed
In contrast , an impairment of collateral recruitment was evident in the Type 2 diabetic db / db mice , which coincided with a worse stroke outcome compared with their normoglycemic counterpart db/+ , despite their equally well - collateralized leptomeningeal anastomoses . - pubmed
Similar to the wild - type mice , both db/+ and db / db mice underwent collateral growth 7 d after MCA stroke , although db / db mice still exhibited significantly reduced retrograde flow into the MCA territory chronically . - pubmed
Acutely induced hyperglycemia in the db/+ mice did not impair collateral flow after stroke , suggesting that the state of hyperglycemia alone was not sufficient to impact collateral flow . - pubmed
Our results suggest that the impaired collateral status contributes to the exacerbated ischemic injury in mice with Type 2 diabetes , and modulation of collateral flow has beneficial effects on stroke outcome among these subjects . - pubmed
Several prognostic factors can predict disease progression and therapeutic outcomes in those patients . - pubmed
Positive voided urine cytology predicts worse pathological findings of nephroureterectomy specimens in patients with upper tract urothelial carcinoma : does selective ureteral cytology have an additional efficacy ? - pubmed
OBJECTIVE : After radical nephroureterectomy , substantial numbers of patients with upper tract urothelial carcinoma are ineligible for adjuvant chemotherapy owing to diminished renal function . - pubmed
Herein , we evaluated pre - operative voided urine cytology and the additional efficacy of selective ureteral cytology for predicting pathological features in upper tract urothelial carcinoma patients . - pubmed
METHODS : This retrospective cohort study comprised 722 patients with upper tract urothelial carcinoma who underwent radical nephroureterectomy . - pubmed
Patients with concomitant bladder cancer and those who received neoadjuvant therapy were excluded . - pubmed
Evaluating the Role of Corticosteroid Pulse Therapy in Patients With Secondary Progressive Multiple Sclerosis Receiving Mitoxantrone : A Double Blind Randomized Controlled Clinical Trial . - pubmed
OBJECTIVES : To evaluate the role of corticosteroid pulse therapy in patients with SPMS receiving mitoxantrone . - pubmed
PATIENTS AND METHODS : A double blind randomized controlled clinical trial was performed on 71 patients with SPMS referred to Shahid Sadoughi Hospital ( Yazd , Iran ) for receiving mitoxantrone in two groups . - pubmed
Many patients with Parkinson ' s disease ( PD ) will develop cognitive impairment . - pubmed
Effect of pregnancy on the activity and infectivity of hepatitis B virus in women with chronic hepatitis B infection . - pubmed
RESULTS : From the result obtained , significance variance ( p<0.05 ) existed between HIV positive persons and persons who tested positive to HIV / HBV / HCV triple infection before and after the commencement of HAART . - pubmed
Cognitive deficits in patients with obsessive - compulsive disorder - electroencephalography correlates . - pubmed
The aim of our study was to examine the association between cognitive impairment and current source density markers in patients with OCD . - pubmed
METHODS : Resting - state eyes - closed electroencephalography ( EEG ) data were recorded in 20 patients with OCD and 15 healthy controls who were involved in the study . - pubmed
RESULTS : Frontal delta and theta EEG sources showed significantly higher activity in the whole group of patients with OCD ( N=20 ) than in control subjects ( N=15 ) . - pubmed
Subsequent analysis revealed that this excess of low - frequency activity was present only in the subgroup of eleven patients with cognitive impairment ( based on the performance in the Trail - Making Test - A ) . - pubmed
CONCLUSION : The present results suggest that frontal low - frequency cortical sources of resting - state EEG rhythms can distinguish groups of cognitively impaired and cognitively intact patients with OCD . - pubmed
Based on our results , future studies should consider whether the present methodological approach provides clinically useful information for the revelation of cognitive impairment in patients with OCD . - pubmed
Despite improved perioperative care , the increasing complexity and extensiveness of surgical interventions , in combination with an expanding number of resections in patients with compromised liver function , still results in an incidence of postresectional liver failure ( PLF ) of 1 - 9 % . - pubmed
Some of the respondents had ever tested for HIV and few had ever been treated for STI more than once . - pubmed
The goal of this study was to explore the prognostic value of these parameters in idiopathic pulmonary arterial hypertension ( IPAH ) patients . - pubmed
Study on AAV - mediated gene therapy for diabetes in humanized liver mouse to predict efficacy in humans . - pubmed
As the results , AAV2 - PG succeeded to improve the hyperglycemia of STZ - induced diabetic humanized liver mice . - pubmed
In PARADIGM - HF , patients with HFrEF treated with sacubitril / valsartan had 20 % less risk for cardiovascular death or hospitalization for heart failure ( the primary endpoint ) , 20 % less risk for cardiovascular death , 21 % less risk for first hospitalization for heart failure , and 16 % less risk for death from any cause , compared with enalapril ( all p & lt ; 0.001 ) . - pubmed
Concerning tolerability , the sacubitril / valsartan group had higher proportions of patients with hypotension and nonserious angioedema but lower proportions with renal impairment , hyperkalemia , and cough , compared with the enalapril group . - pubmed
Cryopreserved porcine hepatocytes isolated from the same strain were suspended in physiological saline and transfused through the catheter . - pubmed
We hypothesized that ADPKD patients have a more severely impaired urine concentrating capacity in comparison to other patients with chronic kidney disease at a similar level of kidney function , with consequently an enhanced AVP response to water deprivation with higher circulating AVP concentrations . - pubmed
METHODS : 15 ADPKD ( eGFR<60 ) patients and 15 age- , sex- and eGFR - matched controls with IgA nephropathy ( IgAN ) , underwent a water deprivation test to determine maximal urine concentrating capacity . - pubmed
In ADPKD patients , height adjusted total kidney volume ( hTKV ) was measured by MRI . - pubmed
METHODS : Sixty - three patients with aSAH between January 2012 and October 2014 , who developed DCI ( defined as new focal deficit or decline in Glasgow Coma Score ) and in which PE ( n = 45 ) or NE ( n = 18 ) treatment was initiated were evaluated in this retrospective study . - pubmed
CONCLUSIONS : Our study suggests that patients with DCI after aSAH initiated on PE are more likely to require treatment change to another vasopressor and are at greater risk for poor clinical outcomes compared to patients started on NE . - pubmed
METHODS : In a case control study , 118 clinically diagnosed Type 2 Diabetes Mellitus ( T2DM ) patients attending Diabetic Clinic at the Nkawie Government Hospital were enrolled between October and December 2015 . - pubmed
When a patient presents with an initial episode of ON , patients should undergo further tests . - pubmed
A Select Subset of Electron Transport Chain Genes Associated with Optic Atrophy Link Mitochondria to Axon Regeneration in Caenorhabditis elegans . - pubmed
Using mechanosensory neurons of the nematode Caenorhabditis elegans to test regeneration after neuronal injury in vivo , we surveyed genes related to mitochondrial function for effects on axon regrowth after laser axotomy . - pubmed
Avian leukosis virus ( ALV ) is an avian oncogenic retrovirus that can induce virus - associated neoplasia and causes great economic loss in poultry industry . - pubmed
Our objective was to demonstrate the diversity of circulating extracellular RNA ( ex - RNA ) release during acute exercise in humans and its relevance to exercise - mediated benefits on vascular inflammation . - pubmed
[ Hyperuricemia in obese patients with pharmacologically treated essential hypertension ] . - pubmed
Thus far , there is no consensus on the treatment of patients with asymptomatic hyperuricemia , despite a large number of studies conducted worldwide . - pubmed
MATERIAL AND METHODS : A total of 109 obese patients ( mean BMI=34.6 + -3.5 kg / m2 ) were included in this study , selected from the outpatients at the Clinic of Arterial Hypertension , the unit of the Cardinal Stefan Wyszynski Institute of Cardiology in Warsaw . - pubmed
CONCLUSION : The incidence of hyperuricemia demonstrated in this study confirms the findings of other authors and indicates a fairly common prevalence of this phenomenon among a population of patients with hypertension . - pubmed
OBJECTIVE : Progesterone supplementation prevents preterm birth ( PTB ) in some high - risk women , but its mechanism of action is unknown . - pubmed
METHODS : Human fetal membranes were collected at elective cesarean at term ( no labor , no infection ; n = 6 ) , washed , and pretreated with / without progesterone ( 125 ng / mL ) for 24 hours . - pubmed
We also discuss the potential clinical utilization of this lncRNA as a diagnostic and prognostic biomarker for cancer patients . - pubmed
Successful Treatment of Osteosarcoma Without Methotrexate in a 13 - Year - Old Boy With Down Syndrome . - pubmed
Osteosarcoma is the most common primary bone tumor in children , and only 1 article in the literature describes a case of osteosarcoma in a patient with Down syndrome . - pubmed
Although osteosarcoma is generally treated with chemotherapy regimens that include high - dose methotrexate , patients with Down syndrome have heightened sensitivity to the toxicities of methotrexate . - pubmed
This case report describes the successful treatment of osteosarcoma in a pediatric patient with Down syndrome without methotrexate . - pubmed
Schisandra chinensis Fructus and Its Active Ingredients as Promising Resources for the Treatment of Neurological Diseases . - pubmed
Here , we set out to characterize the dynamics of macrophage infiltration and their functional contribution to muscle regeneration by comparing young and aged animals upon acute sterile injury . - pubmed
METHODS : A total of 159 patients who had primary osteoarthritis of the knee with varus deformity underwent TKA . - pubmed
METHODS : A retrospective multicentric study analyzed the outcome of patients admitted to the ICU with a newly diagnosed lung cancer ( diagnosis within the month ) between 2010 and 2013 . - pubmed
RESULTS : Out of the 100 patients , 30 had small cell lung cancer ( SCLC ) and 70 had non - small cell lung cancer . - pubmed
CONCLUSION : This study shows that ICU management can be appropriate for selected newly diagnosed patients with advanced lung cancer , and chemotherapy might improve outcome for patients with SCLC admitted for cancer - related complications . - pubmed
WHAT IS KNOWN ALREADY : ICSI is a successful treatment for infertility , but not in all individuals . - pubmed
Conclusion Standard treatment combined LRCD showed better comprehensive effect for dry eyes and dry mouth in pSS patients with FDDOS , and was more safe . - pubmed
The possible sources of iodine in milk are supplemental iodine in dairy feeds , iodophor - containing sanitizers used at the dairy farm and/or the processing plant , iodophor - containing teat dips used to control the spread of mastitis among dairy cows , and iodine - containing medications used by veterinarians . - pubmed
The caged Dex- p - siRNA nanoparticles targeting GFP successfully photoregulated GFP expression in tumor - bearing mice via intratumoral injection . - pubmed
Incidence of and risk factors for cardiotoxicity after fluorouracil - based chemotherapy in locally advanced or metastatic gastric cancer patients . - pubmed
OBJECTIVES : Cardiotoxicity is an important side effect in patients receiving chemotherapy and the application of anthracycline drugs for gastric cancer treatment is uncommon . - pubmed
The purpose of this study was to determine the incidence rate of and risk factors for cardiotoxicity in gastric cancer patients treated with fluorouracil - based chemotherapy . - pubmed
MATERIALS AND METHODS : We retrospectively enrolled patients with locally advanced or metastatic gastric cancer from 2011 to 2016 . - pubmed
The incidence of cardiotoxicity and patients ' clinical data were obtained from hospital clinical databases and manually reviewed . - pubmed
Cardiotoxicity was observed in 38 of 129 patients ( 29.5 % ) . - pubmed
Twelve patients ( 9.3 % ) exhibited toxicity greater than grade 2 , and 2 ( 1.6 % ) patients died of cardiac toxicity . - pubmed
CONCLUSIONS : Chemotherapy - related cardiotoxicity may be underestimated in Chinese gastric cancer patients . - pubmed
Close monitoring for cardiotoxicity and enhanced cardiac management are recommended for patients who receive fluorouracil - based chemotherapy , especially for patients with high - risk factors for serious cardiotoxicity . - pubmed
In the current study , the effects of starch , as the main component in WGF , and beta - glucan in a whole - grain - like structural form ( WGLSF ) on hepatic IR and glucose homeostasis were investigated using high - fat ( HF)-induced obese C57BL/6J mice . - pubmed
After treatment for 8 weeks , the body weight gain and IR of the mice were significantly reduced . - pubmed
Alcohol Binge Drinking and Anxiety - Like Behavior in Socialized Versus Isolated C57BL/6J Mice . - pubmed
Using DID methodology , alcohol - preferring strains of mice such as C57BL/6J ( B6 ) mice consume enough EtOH to achieve blood concentrations ( > = 1.0 mg / ml ) associated with behavioral intoxication ( i.e. - pubmed
METHODS : Male and female B6 mice were isolated or pair - housed for a period of 6 weeks prior to evaluation of anxiety - like ( elevated plus maze , light and dark box , open field ) and drinking ( water , 10 % sucrose , 10 to 30 % EtOH ) behavior . - pubmed
RESULTS : Increased anxiety - like behavior and reduced sucrose consumption were found in isolated mice . - pubmed
An understanding of the genetic network underlying the development and maintenance of this highly specialized region is instrumental to address issues about human macula - related retinopathies . - pubmed
METHODS : A retrospective chart review was performed , identifying all patients treated at our institution from July 2014 - June 2018 with the ICD-10 code N42.89 for prostatic urethral stenosis . - pubmed
RESULTS : Twenty - two patients were identified with the diagnosis of prostatic urethral stenosis . - pubmed
Endoscopic management can be successful in stabilizing patients , while urethroplasty can be feasibly performed in patients with short prostatic apical strictures . - pubmed
We have reported accelerated wound healing induced by intracellular ATP delivery in rabbits , through early massive accumulation , in situ proliferation , and M2 polarization of macrophages . - pubmed
The presented case concerns a 32 - year - old man with clinical diagnosis of ARSACS . - pubmed
BACKGROUND : Quality of hands - only cardiopulmonary resuscitation ( CPR ) is an important determinant of resuscitation outcome for cardiac arrest patients cared for by lay rescuers . - pubmed
We determined the changes in contractile reactivity induced by ATP , uridine triphosphate ( UTP ) , uridine diphosphate ( UDP ) , and Up4A in the femoral arteries of Otsuka Long - Evans Tokushima Fatty ( OLETF ) rats ( aged male type 2 diabetic rats ) and , Long - Evans Tokushima Otsuka ( LETO ) rats ( controls for OLETF rats ) . - pubmed
Label - Free Follow - Up Surveying of Post - Treatment Efficacy and Recurrence in Nasopharyngeal Carcinoma Patients with Fiberoptic Raman Endoscopy . - pubmed
Recurrent nasopharyngeal carcinoma ( NPC ) is the main cause of poor prognosis for NPC patients after chemo- and radiotherapies . - pubmed
Amitraz induced cytotoxic effect on bovine cumulus cells and impaired oocyte maturation . - pubmed
The aim of this study was to evaluate the genotoxic and cytotoxic effects of amitraz ( AMZ ) on the primary culture of bovine cumulus cells ( CC ) and oocyte nuclear maturation . - pubmed
This study contributes to a better understanding of AMZ in this model , suggesting its potential cytotoxicity and impact on bovine reproduction . - pubmed
Treatment with Ramucirumab - paclitaxel in a metastatic gastric cancer patient undergoing hemodialysis : A case report . - pubmed
However , the combination chemotherapy of ramucirumab and cytotoxic drug for hemodialysis ( HD ) patients has not been reported . - pubmed
DIAGNOSIS : The patient was diagnosed with advanced gastric cancer at stage IIIb ( pT3N2M0 ) 11 months ago . - pubmed
LESSONS : The paclitaxel chemotherapy with ramucirumab is effective and safe in HD patients with metastatic gastric cancer . - pubmed
Dahl selectively bred rats for susceptibility ( S strain ) or resistance ( R strain ) to the hypertensive effect of high salt ( NaCl ) diet . - pubmed
Hypertension was found in 18 % of 65 patients with untreated gout , a lower prevalence than that previously reported . - pubmed
The clinical characteristics and renal function of these patients were compared with those of age matched groups of both normotensive gouty subjects and normouricaemic patients . - pubmed
The hypertensive patients had significantly greater body weights than their controls and also had a lower glomerular filtration rate . - pubmed
In preliminary testing , each of the target compounds displayed marginal activity against L1210 leukemia in mice . - pubmed
[ Delayed hypersensitivity in patients with chronic pancreatitis ] . - pubmed
A patient is described in whom breakthrough of pain occurred from uterine rupture during effective extradural analgesia , demonstrating the hypothesis of the " extradural sieve " . - pubmed
Subsequent abolition of this pain by addition of fentanyl to bupivacaine 0.25 % raises the question whether or not this combination should be avoided in women with a scarred uterus undergoing " trial of labour " . - pubmed
MRI in the presurgical evaluation of patients with frontal lobe epilepsy and children with temporal lobe epilepsy : pathologic correlation and prognostic importance . - pubmed
We performed magnetic resonance imaging ( MRI ) using a high - field strength magnet ( 1.5 T ) in two series of 53 patients with intractable partial epilepsy of frontal lobe or temporal lobe origin who subsequently received ablative surgery for their seizure disorder . - pubmed
Twenty - five percent of the patients with negative MRI studies and 67 % of patients with neuroimaging abnormalities restricted to the frontal lobe , were seizure - free at a minimum duration of follow - up of 1 year . - pubmed
None of the patients with a multilobar MRI - detected abnormality was seizure - free postoperatively . - pubmed
In the second study the sensitivity and specificity of MRI - based hippocampal volumetry was determined in pediatric patients with partial epilepsy of temporal lobe origin unrelated to foreign - tissue pathology . - pubmed
Hippocampal formation atrophy in the epileptic temporal lobe was identified in 63 % of patients . - pubmed
The sensitivity and specificity of hippocampal volumetry was 100 % in patients with mesial temporal sclerosis . - pubmed
At the ultrastructural level , signs of low secretory activity were observed in adenomas from patients No . - pubmed
Perifused adenoma cells of patients No . - pubmed
1 , 2 and 3 compared with the adenomas from patients No . - pubmed
However , the signal was more intense in the adenomas from patients No . - pubmed
Failure of lidocaine to suppress lethal ischemic ventricular arrhythmias in a canine model of previous myocardial infarction . - pubmed
lidocaine infusions were assessed in conscious dogs with spontaneous ventricular ectopy subacutely ( 48 h ) after anterior myocardial infarction and in anesthetized dogs with ventricular tachyarrhythmias inducible by programmed ventricular stimulation at 4 - 11 days after anterior myocardial infarction . - pubmed
In conscious dogs administered cumulative doses of lidocaine at 48 h after myocardial infarction , a significant reduction in the frequency of spontaneous ventricular ectopic complexes ( from 61 + /- 12 to 11 + /- 9 % of total complexes ) occurred only after administration of 10 mg / kg i.v . - pubmed
In anesthetized postinfarction dogs responding to baseline programmed stimulation with ventricular tachyarrhythmias , lidocaine administration ( 6 mg / kg i.v . - pubmed
in 5 of 10 postinfarction animals tested , with an additional 3 animals displaying favorable stabilizations of induced arrhythmias.(ABSTRACT TRUNCATED AT 250 WORDS ) - pubmed
Anterior spinal artery syndrome after epidural anesthesia in a pregnant diabetic patient with scleredema . - pubmed
Animal experiment showed that Wei Yang An inhibited the ulcers . - pubmed
Radiotherapy as salvage treatment in patients with Hodgkin ' s disease or non - Hodgkin ' s lymphoma relapsing after initial chemotherapy . - pubmed
[ Disorders of the pyelo - ureteral junction in children apropos of 89 cases in 74 patients ] . - pubmed
Endoscopic or fluoroscopic pyeloureterotomy was performed in a total of 32 patients ( 34 ureters ) with ureteropelvic junction obstruction ( UPJO ) or ureteral stricture from March 1985 . - pubmed
Sixty - seven ( 39 % ) patients had ventricular arrhythmias ( PCC - VT - VF ) , of whom 17 ( 9.8 % ) had VT and 11 ( 6.4 % ) VF . - pubmed
Fifty - six out of 67 ( 83.5 % ) of these patients arrived at Accident & amp ; Emergency ( A&E ) within the first six hours of onset of chest pain . - pubmed
Ten out of 11 ( 91 % ) patients who had VF did so in the first six hours . - pubmed
Forty - three patients ( 84 % ) who had PVCs did not develop any further arrhythmias . - pubmed
Initial manifestation of acute intestinal tuberculosis with miliary involvement in an elderly patient ] . - pubmed
A mixture of heterotrophic bacteria and collection strains of Escherichia coli and Pseudomonas fluorescens were immobilized in calcium alginate or pectate gels . - pubmed
Despite the improved response rate , high - dose chemotherapy has resulted in short response durations and no significant impact on the survival of cancer patients as yet . - pubmed
[ Poisoning with aliphatic hydrocarbons in children ] . - pubmed
This case demonstrates that in a patient with intermittent left bundle branch block a complete AV block may occur and therefore the possibility of cardiopulmonary resuscitation and temporary pacing has to be taken in account . - pubmed
Using programmed ventricular stimulation , which can detect significant ventricular arrhythmias in patients with very little ectopy in 24 - hour electrocardiographic recordings , 20 % of patients have ventricular tachycardia 2 to 6 weeks after acute myocardial infarction ( AMI ) . - pubmed
This finding provides a rationale for treating patients with frequent or repetitive ventricular arrhythmias detected near the time of hospital discharge after AMI . - pubmed
Lacking an answer to this question and given the frequency of adverse effects with antiarrhythmic drugs , most physicians are conservative in the treatment of patients with ventricular arrhythmias after AMI . - pubmed
[ Chronic upper airway obstruction in 2 children ] . - pubmed
Effects of x - irradiation and cortisone treatment of albino rats on infections with Brucei - complex trypanosomes . - pubmed
Distribution of bronchial resistance in obstructive pulmonary diseases and in dogs with artificially induced tracheal collapse . - pubmed
Membrane lipid analyses and electron spin resonance ( ESR ) studies of membrane fluidity were carried out on the red cells of a Japanese patient with hereditary high red cell membrane phosphatidylcholine hemolytic anemia ( HPCHA ) . - pubmed
By analysis of a series of somatic cell hybrids derived by fusion of either mouse or Chinese hamster cells with leukocytes from different chronic myelocytic leukemia ( CML ) patients or from normal donors , we have localized the human oncogene , c - sis , on the q11 to qter segment of chromosome 22 and demonstrated its translocation from chromosome 22 to chromosome 9 ( q34 ) in CML . - pubmed
3.1.1.8 ) ; the activity of both enzymes was raised in amniotic fluid from women carrying open NTDs . - pubmed
Experimental enteritis in cynomolgus monkeys produced by intragastric administration of Salmonella typhimurium . - pubmed
The protein binding of piretanide was assessed by continuous ultrafiltration of sera from six normal subjects and seven uraemic subjects ( samples taken immediately pre - dialysis ) . - pubmed
The three 5 - O - acetylated 6 - O - acylated dipeptidyl furanose derivatives also significantly stimulated production of circulating antibodies against hepatitis B vaccine in mice ; titers were comparable to those observed with the alum - adsorbed vaccine . - pubmed
Polyuria above 3 litres/24 hours was found in 10 % of patients . - pubmed
Structural studies of the saccharide part of the cell envelope lipooligosaccharide from Haemophilus influenzae strain galEgalK. - pubmed
The structure of the saccharide part of the lipooligosaccharide from Haemophilus influenzae strain galEgalK has been investigated . - pubmed
Chronic protein restriction does not alter energetic efficiency or brown adipose tissue thermogenic capacity in genetically obese ( fa / fa ) Zucker rats . - pubmed
Attenuated regulatory thermogenesis in genetically obese ( fa / fa ) Zucker rats involves an impaired capacity to increase sympathetic drive to brown adipose tissue in response to dietary stimuli . - pubmed
Young , growing lean rats fed a low protein diet reduce energetic efficiency to compensate for elevated energy intake ; however , it is not known if obese rats adapt similarly to chronic protein restriction by decreasing energetic efficiency and whether this would be accompanied by increased brown adipose tissue thermogenic capacity . - pubmed
Lean ( Fa / Fa ) and obese Zucker rats were either protein - restricted ( protein 8 % of total energy ) or fed a control diet ( 21 % protein ) starting at age 5 wk . - pubmed
, food intake / body weight 0.67 ) was greater in protein - restricted than in control lean rats , but not different due to diet in obese rats . - pubmed
Mass - adjusted brown adipose tissue uncoupling protein levels were more than 100 % greater in protein - restricted vs. control lean rats , but not different between protein - restricted and control obese rats . - pubmed
The uncoupling protein level was not significantly different in control lean vs. obese rats . - pubmed
Energetic efficiency was 40 % lower in protein - restricted vs. control lean , but not different in obese rats ; however , the efficiency of protein utilization was significantly greater in obese protein - restricted than in obese control rats . - pubmed
Protein efficiency increased to more than two times its original value in obese ( fa / fa ) rats , but otherwise no metabolic accommodation in the capacity for regulatory thermogenesis was observed in this genotype . - pubmed
One group consisted of 99 brain - injured patients , while the other consisted of a group of 17 neurologically normal controls . - pubmed
Central conduction times obtained from the right and left hemispheres were similar in ECMO patients and were not different from those recorded from a group of patients suffering hypoxic - ischemic injuries and a group of normal controls who did not receive ECMO . - pubmed
The results of this pilot study suggest that SEPs may be employed to evaluate ECMO patients as they are in other brain - injured patients . - pubmed
[ Pediatric nursing at home -- six months of home care for a patient with spinal muscular atrophy ] . - pubmed
Clinical variables and laboratory and histologic findings were evaluated in 53 children with IgA nephropathy , of whom 44 were followed for a mean period of 6.2 years ( range 1.2 - 14 ) . - pubmed
At the end of the follow - up 8 patients ( 18.2 % ) had had no urinary anomalies for at least 1 year ( stage A disease ) , 28 ( 63.6 % ) had microscopic hematuria with proteinuria & lt ; 1 g / m2 / day ( stage B ) , 5 ( 11.4 % ) had proteinuria & gt ; 1 g / m2 / day ( stage C ) , and 3 ( 6.8 % ) had chronic renal insufficiency ( stage D ) . - pubmed
Presenting features of gross or microscopic hematuria without or with proteinuria ( & lt ; 0.5 g / m2 / day ) correlated ( p & lt ; .001 ) with minimal glomerular abnormalities at biopsy , whereas patients with nephritic syndrome had more severe histologic pictures . - pubmed
Coumermycin A1 inhibits growth and induces relaxation of supercoiled plasmids in Borrelia burgdorferi , the Lyme disease agent . - pubmed
We have investigated the activity of this coumarin antibiotic on Borrelia burgdorferi , a spirochete and the causative agent of Lyme disease . - pubmed
Increased pulmonary vascular permeability in rats with biliary cirrhosis : role of thromboxane A2 . - pubmed
Rats with liver cirrhosis exhibit arterial hypoxemia and loss of hypoxic pulmonary vasoconstriction similar to some patients with end - stage liver disease . - pubmed
Electron - microscopic sections of lungs from cirrhotic rats demonstrated infiltration with intravascular macrophage - like cells , endothelial cell injury , and interstitial edema . - pubmed
We conclude that pulmonary vascular permeability is increased in rats with biliary cirrhosis and that thromboxane A2 contributes to the pulmonary circulatory abnormalities in cirrhosis . - pubmed
Glycolipid compositions of cells infected by human retroviruses ( human immunodeficiency virus , HIV and/or human T - cell lymphotropic virus type I , HTLV - I ) have been studied . - pubmed
METHOD : Twelve schizophrenic patients and 11 comparison subjects underwent functional MRI of the frontal and temporal lobes . - pubmed
CONCLUSIONS : These preliminary data suggest that functional MRI has the sensitivity to detect differences in activation between comparison subjects and schizophrenic patients during higher cortical functions . - pubmed
These findings are in agreement with PET studies that reported reduced left frontal activation during challenge paradigms for the schizophrenic patients . - pubmed
In females , there was an increase primarily in the incidence of tobacco - related morphologic tumour types ( i.e. - pubmed
In 641 patients ( 20 % ) a surgical tumour resection was carried out . - pubmed
[ Nedocromil sodium as a topical treatment of allergic conjunctivitis due to grasses ] . - pubmed
Thirty - two patients ( 20 males and 12 females , mean age 31 ys ) with seasonal allergic conjunctivitis to grass pollen , were selected for this study . - pubmed
Nedocromil sodium is therefore a valid alternative in the treatment of allergic conjunctivitis to grass pollen . - pubmed
RESULTS : The patient population included 124 patients , 75 men and 49 women with a mean age of 48.4 years and a mean arthritis duration of 14.6 years . - pubmed
Other studies have found that the morphology of rat stellate ganglion neurones is similar to that of superior cervical ganglion cells . - pubmed
However , in strains of rat displaying spontaneous hypertension , dendritic length may be increased . - pubmed
A patient with left unilateral neglect and a slight left hemiparesis participated in three experiments . - pubmed
METHODS : Data from a total of 224 patients with BD , diagnosed between 1982 and 1996 , were analyzed retrospectively . - pubmed
MATERIALS AND METHODS : From August 1990 to April 1994 , 32 patients bearing previously untreated advanced squamous cell carcinoma of the larynx ( 12 stage III and 20 stage IV ) received three courses of high - dose cisplatin ( 100 mg / m2 on day 1 and day 8 every 28 days ) before definitive external radiation therapy with 65 to 70 Gy ( 180 - 200 cGy daily for 6 - 8 weeks ) . - pubmed
RESULTS : With an average follow - up time of 18 months ( range , 6 - 47 ) , 30 patients are evaluable for response and 32 for toxicity . - pubmed
The main acute toxicity was grade 2 - 3 nausea and vomiting in 75 % of patients . - pubmed
Two patients developed renal impairment after the first course of cisplatin . - pubmed
Ototoxicity ( grade 2 - 3 ) was seen in 43 % of patients , and peripheral neuropathy ( grade 2 - 3 ) was observed in 12 % of patients . - pubmed
Bacterial keratitis after photoreactive keratectomy in a young , healthy man . - pubmed
In a rabbit model of chronic ileal inflammation , we previously demonstrated that coupled NaCl absorption was reduced because of an inhibition of Cl-/HCO3 - but not Na+/H+ exchange on the brush - border membrane ( BBM ) of villus cells . - pubmed
PATIENTS : One hundred twenty - five patients in whom cirrhosis was discovered during gastric bariatric operations . - pubmed
MATERIALS AND METHODS : A stone - forming rat model ( model 1 ) with marked tubular dilatation in an entire kidney was produced by rendering Wistar rats ( aged 8 weeks ) hyperoxaluric and hypercalciuric , through compulsorily feeding with 0.12 mL of 5 % ethylene glycol ( in two doses daily ) and 0.5 microgram of vitamin D3 every other day . - pubmed
Peripheral venous blood and subdural fluid were obtained at the time of burr hole surgery from 34 patients with CSH and from 9 with subdural effusion . - pubmed
Agents that have received the most attention include ozone , nitrogen dioxide , hyperoxia , diesel exhaust , tobacco smoke , silica and fibrous materials such as asbestos . - pubmed
Animal models for motor neuron disease . - pubmed
At present , there is no cure for most motor neuron diseases , including amyotrophic lateral sclerosis ( ALS ) , the most common human motor neuron disease -- the cause of which remains largely unknown . - pubmed
Animal models of motor neuron disease ( MND ) have significantly contributed to the remarkable recent progress in understanding the cause , genetic factors , and pathologic mechanisms proposed for this class of human neurodegenerative disorders . - pubmed
Largely driven by ALS research , animal models of MND have proven their usefulness in elucidating potential causes and specific pathogenic mechanisms , and have helped to advance promising new treatments from " benchside to bedside . " - pubmed
This review summarizes important features of selected established animal models of MND : genetically engineered mice and inherited or spontaneously occurring MND in the murine , canine , and equine species . - pubmed
Effect of gentian violet , corticosteroid and tar preparations in Staphylococcus - aureus - colonized atopic eczema . - pubmed
BACKGROUND : In atopic eczema ( AE ) , skin colonization with Staphylococcus aureus plays a possible role in the pathophysiology of the disease . - pubmed
METHODS : Thirty - eight patients with AE were screened for their cutaneous colonization with S. - pubmed
IMT measurements were determined by high resolution B - mode ultrasound imaging of the carotid arteries in 921 participants with NIDDM and 11,964 non - diabetic participants aged 45 - 64 years . - pubmed
BACKGROUND : Detection of occult micrometastasis in regional lymph nodes is crucial for diagnosis and selection of appropriate therapy for patients with pN0 non - small - cell lung carcinoma . - pubmed
Using immunohistochemical staining , we evaluated the impact of detection of occult micrometastasis on the prevalence and prognosis of patients with lung adenocarcinoma of 2.0 cm or less in diameter . - pubmed
METHODS : A total of 103 pN0 disease patients with peripheral lung adenocarcinomas of 2.0 cm or less in diameter were enrolled in this study . - pubmed
RESULTS : Micrometastasis was detected in 49 lymph nodes ( 3.4 % ) of 21 patients ( 20.4 % ) but not in patients with localized bronchioloalveolar carcinoma or localized bronchioloalveolar carcinoma with foci of collapse of alveolar structure . - pubmed
The 5 - year survival rate ( 61.9 % ) of patients with micrometastasis was significantly ( p = 0.0041 ) lower than that of patients without micrometastasis ( 86.3 % ) . - pubmed
MATERIALS AND METHODS : We studied the activities and mRNA expression levels of these enzymes in normal human livers and in human livers with chronic hepatitis , cirrhosis , or hepatocellular carcinoma . - pubmed
In the present investigation , we test the hypothesis that progesterone can rapidly relax , via a nongenomic mechanism , persistent flow occluding , agonist - activated coronary artery ( CA ) vasospasm , and hyperreactive vascular muscle cell ( VMC ) Ca ( 2 + ) responses in ovariectomized rhesus monkeys . - pubmed
Hypotension is a common postoperative complication in the perianesthesia setting and contributes to increased patient morbidity and mortality rates . - pubmed
Prospective evaluation of pain relief in 100 patients undergoing percutaneous vertebroplasty : results and follow - up . - pubmed
Before the procedure and at follow - up , patients were asked to quantify their pain on a visual analog scale ( VAS ) and complete a follow - up questionnaire of our own design . - pubmed
One patient sustained a sternal fracture and one experienced a transient radiculopathy . - pubmed
Ninety - seven patients ( 97 % ) reported significant pain relief 24 hours after treatment . - pubmed
Ninety - two patients ( 93 % ) reported significant improvement in back pain previously associated with their compression fractures as well as improved ambulatory ability . - pubmed
CONCLUSION : Percutaneous vertebroplasty of symptomatic vertebral body compression fractures is a minimally invasive procedure that provides immediate and sustained pain relief in patients with refractory pain . - pubmed
Genetic diversity of echovirus 30 during a meningitis outbreak , demonstrated by direct molecular typing from cerebrospinal fluid . - pubmed
Echovirus 30 is one of the enterovirus serotypes isolated most frequently in meningitis cases . - pubmed
The viral sequences obtained for 22 patients were compared with those of virus isolates obtained from nine patients with echovirus 30 meningitis admitted to hospital in 1996 - 1997 and with echovirus 30 sequences from international databases . - pubmed
Untreated allografted rats developed proteinuria , glomerulosclerosis , and mild intimal hyperplasia . - pubmed
However , parental administration has negative aspects such as multiple injections , possible infection , patient inconvenience , and high cost . - pubmed
Cerebral blood flow and hemodynamics in patients with dizziness resulting from central nervous system disorders . - pubmed
OBJECTIVE : To investigate the changes in regional cerebral blood flow ( RCBF ) and cerebral hemodynamics in patients with dizziness resulted from disorders of the central nervous system . - pubmed
METHOD : Using 133Xe inhalation technique and transcranial Doppler ultrasonography(TCD ) , we measured RCBF and blood flow velocity in the major cerebral arteries in 86 such patients with dizziness , who were divided into persisting and intermittent groups according to the symptoms . - pubmed
RESULT : Decreased RCBF was found in 60.5 % of the patients with also lowered cerebral blood flow velocity , and the abnormalities appeared more serious when the dizziness persisted . - pubmed
CONCLUSION : Measurement of RCBF and cerebral blood velocity in patients with central nervous system - related dizziness but without cerebral structural changes may facilitate the assessment of the degree of pathological changes in RCBF and hemodynamics in the affected area and help to better understand the patterns of these changes , which may consequently assist clinical decisions on the diagnosis and treatment of the disease . - pubmed
[ Isolation of 17 - ketosteroids from the daily urine of patients with chronic tonsillitis ] . - pubmed
We report a 19 - year old woman with lupus nephritis and nephrotic syndrome who had not achieved complete remission after treatment with 15.7 g cyclophosphamide and 13.7 g prednisone . - pubmed
OBJECTIVE : To determine , in spontaneously hypertensive rats ( SHR ) and Wistar - Kyoto ( WKY ) rats , whether acute reductions of the HR in response to ivabradine induced changes in the carotid visco - elastic behavior , as assessed by echo - tracking techniques . - pubmed
Tissue reactions to waxes derived from spool cotton ; possible etiologic relation to suture granulomas and suture extrusion . - pubmed
The mammalian lignan enterolactone ( ENL ) , which is produced from dietary plant - lignan precursors by the intestinal microflora , may protect against breast cancer and other hormone - dependent cancers . - pubmed
In conclusion , whole grains and vegetables are the most important dietary providers of plant lignans for the concentration of ENL in Danish postmenopausal women , and if ENL is found to protect against cancer or heart disease , the intake of whole grains and vegetables should be increased . - pubmed
METHODS : Of 84 patients with histologically proven HCC by hepatectomies , multiphasic helical CT demonstrated 54 HCC lesions of intrahepatic recurrence in 31 ( 37 % ) patients . - pubmed
Does donepezil treatment slow the progression of hippocampal atrophy in patients with Alzheimer ' s disease ? - pubmed
METHOD : In a prospective cohort study , 54 patients with Alzheimer ' s disease who received donepezil treatment and 93 control patients with Alzheimer ' s disease who never received anti - Alzheimer drugs underwent magnetic resonance imaging ( MRI ) twice at a 1 - year interval . - pubmed
METHODS : Forty two specimens of colorectal cancer and normal colorectal mucosa were investigated , taken from the colon or rectum in group of colorectal cancer patients . - pubmed
OBJECTIVE : To assess benign prostatic hyperplasia ( BPH ) and erectile dysfunction ( ED ) , both considered to be associated with urogenital ageing , in ageing men in a cross - sectional population study , comparing them with healthy controls by using symptom scores and contrast - enhanced colour Doppler ultrasonography ( CDUS ) . - pubmed
CDUS was performed using the microbubble - based ultrasound enhancer for evaluating prostate , bladder neck and corpus cavernosum vascularity in young healthy men , men with BPH , and men with severe vascular damage ( diabetes mellitus type 2 ) . - pubmed
RESULTS : In patients with BPH , perfusion of the transition zone ( TZ ) of the prostate was significantly lower and the resistive index of the TZ significantly higher ( both P & lt ; 0.001 ) than in healthy controls . - pubmed
In patients with BPH the IPSS , quality - of - life and IIEF scores were significantly worse than in the control group . - pubmed
Twelve ( 7 male and 5 female ) athletes were randomly assigned into two groups and spent 8 h per night for two consecutive nights a week over 3 weeks under either short - term normobaric hypoxia ( simulating 3636 m altitude , inspired O2=13 % ) or in normobaric normoxia in a single - blind study . - pubmed
The patients at risk for infection were given valgancyclovir as prophylaxis throughout the study . - pubmed
[ Effect of glutamine depletion on immunity and other organ function in critically ill patients ] . - pubmed
OBJECTIVE : To evaluate the effect of glutamine depletion on immunity and other organ function in critically ill patients . - pubmed
CONCLUSION : In critically ill surgical patients glutamine depletion is evident , and the reduction in plasma Gln is related to immunosuppression and organ dysfunction . - pubmed
METHODS : Observational descriptive study of 16 ( sixteen ) eyes of 16 patients with unilateral acute central serous chorioretinopathy . - pubmed
RESULTS : Of the 16 central serous chorioretinopathy eyes , 12 patients completed follow - up until total resolution of their disease . - pubmed
Pineal parenchymal tumour of intermediate differentiation ( PPTID ) in adults is rare and a treatment strategy for this condition has not yet been established . - pubmed
This 60 - year - old man presented with a 3 - month history of memory disturbance , gait instability and double vision . - pubmed
Little is known about the clinical behaviour of PPTID in adults . - pubmed
[ Researching the influence of animal feed in dogs with a congenital porto - systemic shunt ] . - pubmed
Intravenous glutamine supplementation to head trauma patients leaves cerebral glutamate concentration unaffected . - pubmed
nutrition for neurosurgical patients , as this may result in elevated intracerebral glutamate levels , which are thought to be associated with neuronal injury and cell swelling , causing an increase in ICP and an unfavourable outcome . - pubmed
SUBJECTS : Patients with severe head trauma ( GCS<or=8 ; n=15 ) on routine monitoring , including intracerebral microdialysis , were randomly assigned to treatment followed by placebo or placebo followed by treatment . - pubmed
We report a patient with chemotherapy - naive advanced pancreatic cancer having multiple liver metastases which dramatically responded to S-1 , an oral fluoropyrimidine . - pubmed
Gene expression profiling of islets from pre - diabetic male Zucker diabetic fatty ( ZDF ) rats showed increased expression of hypoxia - related genes , prompting investigation of the vascular integrity of the islets . - pubmed
These data suggest that in the ZDF rat model of type 2 diabetes , an inability of the islet to maintain vascular integrity may contribute to beta - cell failure . - pubmed
We present two children discovered to have a total cataract in one eye with a posterior subcapsular cataract in the other eye . - pubmed
We conclude that the pulmonary infection of M. - pubmed
This presents a proof of concept for device based baroreflex modulation in acute BP regulation and adds to the available data which provide a rationale for evaluating this system in the context of chronic BP reduction in hypertensive patients . - pubmed
Spores of 11 enterotoxigenic strains of Bacillus cereus isolated from foods and humans adhered with similar efficiencies to Caco-2 cells , whereas subsequent germination triggering was observed with only 8 of these strains . - pubmed
Time to coronary angiography and outcomes among patients with high - risk non ST - segment elevation acute coronary syndromes : results from the SYNERGY trial . - pubmed
BACKGROUND : Optimal timing for an early invasive strategy in patients with non - ST - segment - elevation acute coronary syndrome remains unclear . - pubmed
We evaluated the relationship between time from hospital admission to coronary angiography and outcomes in high - risk patients with non - ST - segment - elevation acute coronary syndrome who underwent angiography within 48 hours of admission . - pubmed
The adjusted odds ratio for death / myocardial infarction in patients receiving angiography in & lt;6 hours was 0.56 ( 95 % confidence interval 0.41 to 0.74 ) , whereas after 30 hours , there was no significant benefit compared with further delayed angiography . - pubmed
COLOBOMATA OF THE OPTIC NERVE SHEATH IN RATS . - pubmed
[ Cardiac symptoms due to pectus excavatum in a man over the age of 55 ] . - pubmed
A healthy 59 - year - old man , a retired general practitioner , suffered from increasing palpitations , fatigue and postural dyspnoea : bending over led to a significant increase in his shortness of breath . - pubmed
[ Effect of the acetylosalicyd acid ( ASA ) and ticlopidine therapy on clinical condition and parameters of blood platelets in patients with peripheral arterial occlusive disease ( PAOD ) ] . - pubmed
RESULTS : Supplementation therapy with ASA or ticlopidine to the standard therapy with pentoxyphylline resulted in a marked increase in the distance of claudication evaluated subjectively and objectively on moving track and revealed silent myocardial ischemia in 4 PAOD patients . - pubmed
CONCLUSIONS : Both antiplatelet drugs have beneficial effect on clinical condition of PAOD patients and the effect may results from their anti - aggregative and anti - adhesive properties . - pubmed
One hundred non - dialysis patients with chronic kidney disease over 18 years of age were evenly split into anemic and non - anemic cohorts . - pubmed
Of the 50 anemic patients , 23 were receiving erythropoiesis stimulating agents treatments . - pubmed
METHODS : Ninety - two steroid - naive and twenty - eight steroid - treated asthmatic patients were enrolled . - pubmed
FU + L ( FUL ) are frequently combined with oxaliplatin ( OXA ) in advanced colon cancer patients . - pubmed
Prognostic value of intra - operative lateral spread response monitoring during microvascular decompression in patients with hemifacial spasm . - pubmed
Among these 32 patients , 11 had mild HFS at discharge and six had mild HFS at the 6 month follow up . - pubmed
Out of the 40 patients in whom the LSR disappeared intra - operatively after MVD , five had mild HFS at discharge and four had mild HFS at the 6 - moth follow up . - pubmed
Tailoring treatment according to risk of disease recurrence , patient life expectancy , comorbidity , risk factors for cardiovascular disease or osteoporosis and compliance is necessary . - pubmed
Rearrangement of the JC virus regulatory region sequence in the bone marrow of a patient with rheumatoid arthritis and progressive multifocal leukoencephalopathy . - pubmed
The polyomavirus JC ( JCV ) is the etiologic agent of progressive multifocal leukoencephalopathy ( PML ) . - pubmed
Further studies will be needed to determine the prevalence of JCV in bone marrow of immunosuppressed individuals at risk of PML and characterize the RR and phenotype of these JCV isolates . - pubmed
Immune responses of humans and animals are impaired by sleep loss , and responses to immune challenge include altered sleep . - pubmed
Ribotyping , biotyping and capsular typing of Haemophilus influenzae strains isolated from patients in Campinas , southeast Brazil . - pubmed
Forty - five Haemophilus influenzae strains isolated from patients were characterized based on biochemical characteristics . - pubmed
Placental transmogrification of the lung has been considered a variant of unilateral bullous emphysema , but in our case , the patient was a 47 - year - old man who had no coexisting emphysema of the lung . - pubmed
Hydrogen - rich saline reduces lung injury induced by intestinal ischemia / reperfusion in rats . - pubmed
In this study we investigated the effects of hydrogen - rich saline on the prevention of lung injury induced by intestinal ischemia / reperfusion ( I / R ) in rats . - pubmed
BACKGROUND : Though antidepressant drugs are the treatment of choice for severe major depression , a number of patients do not improve with pharmacologic treatment . - pubmed
This study aimed to assess the effects of transcranial direct current stimulation ( tDCS ) in patients with severe , drug - resistant depression . - pubmed
CONCLUSIONS : We conclude that frontal tDCS is a simple , promising technique that can be considered in clinical practice as adjuvant treatment for hospitalized patients with severe , drug - resistant major depression . - pubmed
Pharmacokinetics of ceftriaxone in carbontetrachloride - induced hepatopathic and uranyl nitrate - induced nephropathic goats following single dose intravenous administration . - pubmed
The pharmacokinetic profile of ceftriaxone was studied in female healthy goats , induced hepatopathic and nephropathic goats after a single intravenous dose at 50 mg kg(-1 ) . - pubmed
Ceftriaxone persisted for 2 h in plasma of hepatopathic goats compared to 1 h of healthy goats , but the kinetic behaviour followed ' one - compartment open model ' in both healthy and hepatopathic goats . - pubmed
Ceftriaxone was recovered at 24 h in urine of hepatopathic goats but it could not be detected in urine of healthy goats . - pubmed
However , its metabolite ceftizoxime was present in urine of healthy goats but not in urine of hepatopathic goats . - pubmed
Elimination halflife ( t(1/2)beta ) of Elimination ceftriaxone ( 0.38 + /- 0.01 h ) in nephropathic goats increased significantly compared to healthy goats ( 0.19 + /- 0.002 h ) . - pubmed
PATIENTS / MATERIALS AND METHODS : 226 patients with exsudative AMD and 179 controls without AMD were included . - pubmed
Failure of tooth eruption in two patients with cerebral palsy and bruxism - a 10 - year follow - up : a case report . - pubmed
The aim of this paper was to analyze delayed tooth eruption in two children with cerebral palsy who had severe bruxism and to determine whether treatment could influence tooth eruption and alignment . - pubmed
Bariatric surgery was cost - effective at 2 years for management of type 2 diabetes in obese patients . - pubmed
Off - pump coronary artery bypass grafting no - touch surgery can be the treatment of choice for patients with three - vessel disease and left main stenosis . - pubmed
Peripheral edema is a common and dose - dependent adverse event seen with dihydropyridine CCBs , which can cause marked patient distress , reduce adherence to therapy , and result in dose reduction or even discontinuation of therapy . - pubmed
The protective role of anandamide in mesenteric ischemia reperfusion injury in guinea pig . - pubmed
Women in the continuous group reported significantly fewer bleeding days requiring protection and were more likely to have amenorrhea ; in addition they also reported significantly fewer days of bloating and menstrual pain . - pubmed
At the end of the 1 - year trial amenorrhea was present in 58.7 % of the women and a complete absence of bleeding in 79.0 % . - pubmed
METHODS : Fifteen patients ( mean age , 41.9 years ) who had symptomatic osteochondral lesions of the talus with a mean volume of 6059 mm(3 ) underwent fresh matched osteochondral allograft transplantation . - pubmed
All patients were followed prospectively for a minimum of two years and were evaluated with use of the pain score on a visual analog scale , which ranged from 0 to 10 , and the American Orthopaedic Foot and Ankle Society ankle - hindfoot score , which had a maximum of 100 points . - pubmed
With the scores for these patients included ( at the time of arthrodesis ) , the mean pain score had improved from 8.5 to 3.3 and the mean American Orthopaedic Foot and Ankle Society ankle - hindfoot score had improved 45 points , from 38 to 83 points . - pubmed
We analyzed miRNA expression profiles in 25 pairs of HCC and adjacent non - tumor liver tissues from HCC patients using miRNA microarray . - pubmed
A case of multiple organ tuberculosis ( TBc ) involving lung , pleura , and peritoneum in a 39 - year - old man with long - standing ankylosing spondylitis ( AS ) treated with adalimumab was presented . - pubmed
METHODS : Immunohistochemical staining was performed on pelvic autonomic nerve specimens resected from 17 patients with p - Stage I - III lower rectal cancers . - pubmed
This report presents the case of a 20 - year - old female patient exhibiting an infraoccluded ankylosed maxillary central incisor that was avulsed and replanted after traumatic injury during childhood . - pubmed
Invasion of red blood cells ( RBCs ) by the Plasmodium falciparum malaria merozoite is mediated by parasite surface molecules and proteins contained within apical organelles that are capable of recognizing receptors on the membrane of RBCs . - pubmed
Acute renal dysfunction in a patient presenting with rhabdomyolysis due to Hypothyroidism attributed to Hashimoto ' s Disease . - pubmed
We describe a patient with rhabdomyolysis and acute renal dysfunction due to hypothyroidism , attributed to Hashimoto ' s disease . - pubmed
The disease malaria , caused by the parasite Plasmodium falciparum , remains one of the most important causes of morbidity and mortality in sub - Saharan Africa . - pubmed
Our findings open the door to development of new drugs and patents , especially for CMTs that lack antibiotic activity ( US 7649113 ) , for treatment of human allergic disease . - pubmed
Does antiepileptogenesis affect sleep in genetic epileptic rats ? - pubmed
Recently it was established that early long lasting treatment with the anti - absence drug ethosuximide ( ETX ) delays the occurrence of absences and reduces depressive - like symptoms in a genetic model for absence epilepsy , rats of the WAG / Rij strain . - pubmed
Renal complications correlate with electrical atrial vulnerability hallmarks in type 2 diabetic patients . - pubmed
INTRODUCTION : Liver cirrhosis has been shown to be associated with impaired outcome in patients who underwent elective surgery . - pubmed
We therefore investigated the impact of alcohol abuse and subsequent liver cirrhosis on outcome in multiple trauma patients . - pubmed
MATERIALS AND METHODS : Using the multi - centre population - based Trauma Registry of the German Society for Trauma Surgery , we retrospectively compared outcome in patients ( ISS & gt;= 9 , & gt;= 18 ) with pre - existing alcohol abuse and liver cirrhosis with healthy trauma victims in univariate and matched - pair analysis . - pubmed
CONCLUSIONS : Patients suffering from liver cirrhosis presented impaired outcome after multiple injuries . - pubmed
Spray - applied cell therapy with human allogeneic fibroblasts and keratinocytes for the treatment of chronic venous leg ulcers : a phase 2 , multicentre , double - blind , randomised , placebo - controlled trial . - pubmed
BACKGROUND : Many patients with venous leg ulcers do not heal with standard care . - pubmed
METHODS : We enrolled adult outpatients from 28 centres in the USA and Canada with up to three ulcers , venous reflux confirmed by doppler ultrasonography , and adequate arterial flow in this phase 2 , double - blind , randomised , placebo - controlled trial if at least one ulcer measured 2 - 12 cm(2 ) in area and had persisted for 6 - 104 weeks . - pubmed
Adverse events were much the same across all groups , with only new skin ulcers and cellulitis occurring in more than 5 % of patients . - pubmed
These have greatly improved the outlook and prognosis for diabetic patients with ischemic foot problems . - pubmed
A stroke patient with impairment of auditory sensory ( echoic ) memory . - pubmed
Here , we have investigated the re - innervation patterns of epidermal and dermal nerve fibers in a rat neuropathic pain model . - pubmed
Generally 18 patients out 37 patients referred with biochemical relapse were confirmed to have bone involvement . - pubmed
Selection for qacA carriage in CC22 , but not CC30 , methicillin - resistant Staphylococcus aureus bloodstream infection isolates during a successful institutional infection control programme . - pubmed
BACKGROUND : Syncope , dyspnea , and chest pain are well - established indications for aortic valve replacement in patients with severe AS . - pubmed
Patients ' survival is limited once they develop symptoms from AS , and survival depends on what type of symptoms a patient develops . - pubmed
METHODS : We analyzed 498 patients ( men : 58.4 % , 66 + - 12 years of age ) with severe AS and normal left ventricular ejection fraction from 2003 to 2009 who had comprehensive echocardiography examination for AS . - pubmed
Compared with the asymptomatic group , symptomatic patients were older and had lower cardiac output , and higher E / e ' ratio while having a similar aortic valve area and gradient . - pubmed
Pennyroyal was thought to prevent infection and potatoes were used to relieve pain . - pubmed
PATIENTS : Twenty - six patients with CIS / MS in active relapse , 10 patients with other autoimmune disorders , 12 patients with neuroinfectious diseases , and 15 patients with noninflammatory neurological diseases . - pubmed
Cohort studies have shown that vegetables and fruits protect against coronary heart disease , whereas whole grains provide protection against cardiovascular disease , type 2 diabetes , and weight gain . - pubmed
Randomised clinical trial : evaluation of the efficacy of mesalazine ( mesalamine ) suppositories in patients with ulcerative colitis and active rectal inflammation -- a placebo - controlled study . - pubmed
Mild - to - moderate UC patients with rectal inflammation were randomly assigned either a 1 g mesalazine or placebo suppository . - pubmed
The percentage of patients without bleeding was significantly higher in the mesalazine group than the placebo group from Day 3 of treatment ( P = 0.0001 , Fisher 's exact test ) . - pubmed
CONCLUSIONS : The effectiveness of mesalazine suppositories in all types of UC patients with rectal inflammation was confirmed for the first time in a double - blind , placebo - controlled , parallel - group study ( JapicCTI- 111421 ) . - pubmed
Ultrasound guided brachial plexus block can be advantageous in patients with avulsion type upper extremity injuries . - pubmed
This report describes a 43 - year - old patient who , after allogeneic bone marrow transplantation , developed an oral squamous cell carcinoma secondary to the use of azathioprine , cyclosporine , prednisone , and tacrolimus , associated with multiorgan chronic graft - versus - host disease involving the oral mucosa , skin , eyes , and liver . - pubmed
This report aims to discuss the possible role of immunosuppressant therapy for chronic graft - versus - host disease on the development of oral squamous cell carcinoma , and the relevance of a close oral follow - up of patients to detect dysplastic or malignant alterations at an early stage . - pubmed
Management and treatment of liver injury in children . - pubmed
BACKGROUND : We aimed to assess the causes of trauma that result in liver injury and additional solid organ injuries , management types and results of management in children referred to our clinic for liver injuries . - pubmed
METHODS : The records of 52 patients who were managed for liver injuries due to blunt abdominal trauma between January 2005 - 2010 were reviewed retrospectively . - pubmed
Forty - five patients ( 87 % ) were managed conservatively in this series of liver injury , whereas seven patients ( 13 % ) who had unstable vital signs underwent surgery . - pubmed
CONCLUSION : As a result , conservative management should be preferred in patients with liver injuries who are hemodynamically stable . - pubmed
We aimed to study the clinical , biochemical and extra skeletal manifestations of untreated CKD - MBD in pre - dialysis Stage 4 and 5 CKD patients attending nephrology out - patient clinic at a tertiary care hospital in South India . - pubmed
Of the 710 patients surveyed , 45 % had no CKD - MBD related symptom . - pubmed
A patient with severe pulmonary hypertension for hip arthroplasty . - pubmed
The plant pathogenic fungus Fusarium fujikuroi is the causal agent of bakanae disease on rice due to its ability to produce gibberellins . - pubmed
Half dosage of this gene in humans causes most of the features of the DiGeorge or Velocardiofacial syndrome phenotypes , including aortic arch and cardiac outflow tract abnormalities . - pubmed
Silk fibroin nanoparticles constitute a vector for controlled release of resveratrol in an experimental model of inflammatory bowel disease in rats . - pubmed
PURPOSE : We aimed to evaluate the intestinal anti - inflammatory properties of silk fibroin nanoparticles , around 100 nm in size , when loaded with the stilbene compound resveratrol , in an experimental model of rat colitis . - pubmed
The biological effects of the resveratrol - loaded nanoparticles were tested both in vitro , in a cell culture of RAW 264.7 cells ( mouse macrophages ) , and in vivo , in the trinitrobenzenesulfonic acid model of rat colitis , when administered intracolonically . - pubmed
The moderate negative correlation pairs ( rp ) between remaining Alcian blue and amount of Na (+ ) adsorbed on EPS from strains TN114 and PP803 were -0.652 and -0.609 . - pubmed
The principal component from EPS of strain PP803 which was responsible for salt removal was purified and it was identified as a polysaccharide ( 18 kDa ) mainly composed of galacturonic acid . - pubmed
Important recent advances include the development of mouse models and patient - derived induced pluripotent stem cell ( iPSC ) lines that enable a detailed investigation of synaptic deficits and the identification of potential targets for therapy . - pubmed
In these extended studies the analgesic activity of two tested compounds ( 4c , 4f ) was confirmed in some animal models of pain . - pubmed
Both compounds decreased the edema formation and one of them ( 4c ) attenuated mechanical hyperalgesia in carrageenan - induced paw inflammation in rats . - pubmed
Furthermore , both compounds inhibited cell migration , plasma exudation and nociceptive reaction in zymosan A - induced mouse peritonitis . - pubmed
In the present study , we examined whether oral administration of MA128 suppressed the in vivo tumor growth of HT1080 cells in athymic nude mice . - pubmed
In particular , none of the mice treated with MA128 exhibited systemic toxicity , such as body weight loss or liver and kidney dysfunction . - pubmed
Susceptibility to antimicrobials of mastitis - causing Staphylococcus aureus , Streptococcus uberis and Str . - pubmed
OBJECTIVE : To compare the antimicrobial susceptibility patterns of three common mastitis pathogens ( Staphylococcus aureus , Streptococcus uberis and Str . - pubmed
Long - term prognostic significance of admission plateletcrit values in patients with non - ST elevation myocardial infarction . - pubmed
The objective of our study was to investigate the role of admission plateletcrit in predicting long - term cardiovascular mortality in patients presenting with non - ST - segment elevation myocardial infarction ( NSTEMI ) . - pubmed
We enrolled 296 patients with NSTEMI ( mean age 59.2 + - 11.8 years ; 228 men , 68 women ) in this study . - pubmed
Long - term major advanced cardiac events ( MACE ) , hospitalization for heart failure and reinfarction were significantly higher in patients with high plateletcrit . - pubmed
Admission plateletcrit is a strong and independent predictor of long - term cardiovascular mortality in patients with NSTEMI . - pubmed
Reduction of body fat and improved lipid profile associated with daily consumption of a Puer tea extract in a hyperlipidemic population : a randomized placebo - controlled trial . - pubmed
OBJECTIVE : The goal for this study was to evaluate the effects of daily consumption of Puer tea extract ( PTE ) on body weight , body - fat composition , and lipid profile in a non - Asian population in the absence of dietary restrictions . - pubmed
Analysis of prehospital care and emergency room treatment of patients with acute traumatic spinal cord injury : a retrospective cohort study on the implementation of current guidelines . - pubmed
OBJECTIVES : The aims of the current study were ( i ) to analyze prehospital and emergency room treatment of patients with acute traumatic spinal cord injury ( SCI ) and ( ii ) to analyze whether recommendations given by the current guidelines are implemented . - pubmed
Immobilization was performed on 69.9 % of the patients with traumatic SCI . - pubmed
From 60 patients suffering from cervical traumatic SCI , 47 patients had a cervical collar . - pubmed
In this article , we evaluated the sonosensitizing activity and mode of action of 5 - ALA / PpIX by using mouse mammary tumor EMT6 cells . - pubmed
CONCLUSION : 5 - ALA - SDT showed an antitumor effect in mouse mammary tumor EMT6 cells through oxidation of the mitochondrial membrane via ROS production . - pubmed
The objective of this study was to determine whether alterations in adipose tissue mass arising from food consumption modify the inflammatory response of antigen - induced joint inflammation in mice . - pubmed
RESULTS : PAT volumes were significantly increased in patients with chronic MDD>patients with acute MDD>CTRL . - pubmed
Adrenal gland volume was slightly enlarged in patients with chronic MDD>acute MDD>CTRL , although this difference failed to reach significance . - pubmed
CONCLUSION : Our results extend the existing literature in demonstrating that patients with chronic MDD have the highest risk for developing cardiovascular disorders , indicated by the highest PAT volume and prevalence of metabolic syndrome . - pubmed
Metabolic monitoring , health advices and motivation for the improvement of physical fitness may be recommended in depressed patients , in particular in chronic depression . - pubmed
Pharmacodynamic evaluation was performed using the MK-801 - induced schizophrenic behavioural mouse model , and the sustained suppressive effect lasted two weeks . - pubmed
A stable drug plasma concentration was detected in mice both intraday and interday from 8 to 22 d after a single injection of isoperidone microspheres , and a sustained suppressive effect on the schizophrenic model was also observed . - pubmed
METHODS : Forty - eight patients with IBD ( 24 ulcerative colitis , 24 Crohn ' s disease ) and 40 matched healthy control individuals were enrolled . - pubmed
When compared to control group , in patients with Crohn ' s disease serum homocystein levels were significantly higher ( p = 0.025 ) while serum folic acid levels were significantly lower ( p & lt ; 0.019 ) . - pubmed
Preliminary assessment of Neck Circumference in Benign Prostatic Hyperplasia in Patients with Metabolic Syndrome . - pubmed
The BPH patients were enrolled and were divided into 2 groups : with MtS ( Group 1 ; n=94 ) and without MtS ( Group 2 ; n=103 ) . - pubmed
RESULTS : PPD was detected in 70 postpartum women . - pubmed
Polymorphonuclear neutrophils ( PMNs ) have previously been reported to mediate phagocytosis of anti - CD20 - opsonized B cells from patients with chronic lymphocytic leukemia ( CLL ) . - pubmed
We conclude that PMNs mediate mostly trogocytosis rather than phagocytosis of anti - CD20 - opsonized CLL B cells , and we discuss the implications of this finding in patients with CLL treated with rituximab or obinutuzumab in vivo . - pubmed
A total of nine patients with stage I , left - sided breast cancer who underwent breast - conserving surgery were selected for this retrospective study . - pubmed
At our hospital , we performed a retrospective study of 39 HD and 51 non - HD patients with echocardiography - confirmed IE between June 2000 and February 2007 . - pubmed
The number of patients with diabetic mellitus in these two groups was significantly different ( 28.2 % HD vs 5.9 % non - HD patients ) . - pubmed
By contrast , the erythrocyte sedimentation rate was significantly higher in the HD patients ( HD vs non - HD : 87.2 + -33.32 vs 52.96 + -28.19 ) . - pubmed
The HD patients had a significantly higher Staphylococcus aureus infection rate ( HD : 46.2 % ; non - HD : 27.5 % ) . - pubmed
aureus ( MRSA ; 83.8 % ) infection accounting for S. - pubmed
Conclusion : In patients with similar tumor burden , liver resection combined with intraoperative RFA for unresectable CLM can achieve long - term outcomes similar to hepatectomy alone for resectable CLM . - pubmed
Hypokalemia was associated in six patients . - pubmed
Human papillomavirus ( HPV ) is the second most common cause of cervical cancer worldwide . - pubmed
The aim of this study was to determine the prevalence of HPV and HPV types in women with a normal cytology of the cervix living in the upper and lower regions of Punjab , Pakistan , and to analyze the risk factors for HPV in this region . - pubmed
This study highlights the need to conduct robust epidemiological studies in the region and to develop regular HPV screening so that the situation does not reach an alarming stage resulting in cervical cancer . - pubmed
MiRNAs found differentially expressed in symptomatic compared with presymptomatic mutation carriers were further evaluated in a cohort of 17 patients with sporadic FTD , 13 patients with sporadic Alzheimer ' s disease ( AD ) and 10 healthy controls ( HCs ) of similar age . - pubmed
Aim : To evaluate the efficacy of antihistamines in reducing pruritus in psoriasis , 61 patients were randomized to be treated for 1 week with clemastine ( n = 20 ) , levocetirizine ( n = 21 ) or placebo ( n = 20 ) . - pubmed
Conclusions : Antihistamines of the first and second generations seem to be effective in reducing itch in patients with psoriasis , albeit the antipruritic effect is rather moderate . - pubmed
In the United States , the most common vectorborne pathogens are transmitted by ticks or mosquitoes , including those causing Lyme disease ; Rocky Mountain spotted fever ; and West Nile , dengue , and Zika virus diseases . - pubmed
Transmission in Puerto Rico , the U.S. Virgin Islands , and American Samoa accounted for most reports of dengue , chikungunya , and Zika virus diseases ; West Nile virus was endemic , and periodically epidemic , in the continental United States . - pubmed
BACKGROUND : We aim to investigate factors that may contribute to failure of eradication of dysplastic Barrett ' s Esophagus among patients undergoing radiofrequency ablation treatment . - pubmed
RESULTS : A total of 107 patients underwent radiofrequency ablation for Barrett 's Esophagus , the majority white , overweight , and male . - pubmed
Before treatment , 63 patients had low - grade dysplasia , and 44 patients had high - grade dysplasia or carcinoma . - pubmed
Complete eradication was achieved in a majority of patients ( 57 % for metaplasia , and 76.6 % for dysplasia ) . - pubmed
There is controversy regarding its use in younger women because of their underrepresentation in trials and the concern for late toxicity . - pubmed
Objective : The aim of the present study was to assess the correlation between patient history , physical examination , and electrophysiological method of assessment in patients with clinical suspicion of carpal tunnel syndrome ( CTS ) . - pubmed
Patients and Methods : Results of electrophysiological examinations performed from 2009 to 2016 on 3151 hands of 2516 patients who had symptoms that clinically suggested CTS were examined retrospectively . - pubmed
Patients were assessed in terms of age , gender , direction of nerve compression , and presence and degree of CTS as determined electrophysiologically . - pubmed
Objective : To analysis teratogenic effect of GDC-0449 to fetus and set up the animal model of GDC-0449 induced oromandibular limb hypogenesis in mouse for further research of its pathogenesis . - pubmed
Results : The mice were exposed to GDC-0449 on E11.5 and E12.5 had a high incidence of cleft palate . - pubmed
This work established a novel mouse model for oromandibular limb hypogenesis . - pubmed
Patients with RCC after kidney transplantation were matched in a 1:2 ratio with those without RCC using the indication for transplantation , age at transplantation ( + - 10 years ) , recipient sex ( male / female ) , number of received transplants , living organ donor transplantation ( yes / no ) , and time of follow - up in days as matching criteria . - pubmed
BACKGROUND : Talazoparib ( 1 mg / day ) exhibited promising efficacy and safety in patients with advanced breast cancer during ABRAZO ( NCT02034916 ) ; this study evaluated patient - reported outcomes ( PROs ) . - pubmed
The axial effective stress and the radial displacement in the intervertebral disc , as well as the fluid loss in the nucleus pulposus , increased , whereas the pore pressure in the nucleus pulposus decreased with increased vibrational frequency under the same vibrational time , which may aggravate the injury degree of human lumbar spine . - pubmed
Analgesic effects of the novel alpha2delta ligand mirogabalin in a rat model of spinal cord injury . - pubmed
In the present study , we investigated the analgesic effects of mirogabalin in a rat model of spinal cord injury as an experimental animal model for central neuropathic pain . - pubmed
The spinal cord injury model was established by acute compression of the spinal cord at the T6/7 level with a microvascular clip in male rats . - pubmed
Twenty - eight days after spinal cord injury , the animals received the test compound orally , and the paw withdrawal threshold to mechanical stimulation was determined using the von Frey test at 0 ( before administration ) , 2 , 4 , 6 , 8 , and 24 h after administration . - pubmed
In rats subjected to spinal cord injury , mechanical allodynia was demonstrated by a decreased paw withdrawal threshold . - pubmed
In conclusion , mirogabalin showed potent and long - lasting analgesic effects in a rat model of spinal cord injury and may therefore provide effective pain relief for patients with central neuropathic pain . - pubmed
In this article , we present a case of intravenous BNC and concomitant oral pregabalin misuse that developed in a monitored and treated patient for the reason of opioid dependence . - pubmed
The objective of this study was to compare the transcriptome of human palatal mucosa with chronic oral stomatitis - associated Candida albicans infection to that of healthy oral mucosa . - pubmed
CASE PRESENTATION : We report herein our experience with a case of minor salivary gland sialolithiasis in a 67 - year - old woman . - pubmed
Normalized mean values for patients with benign cysts were 0.65 ( n=57 ) and malignant cysts were 1.85 ( n=54 ) , demonstrating a significantly ( P<0.01 ) higher Hp in malignant samples . - pubmed
Economic burden and treatment patterns for patients with diffuse large B - cell lymphoma and follicular lymphoma in the USA . - pubmed
PATIENTS : Consecutive patients seen at a primary care institution 's Sports Concussion Clinic for sport - related concussion that underwent diffusion tensor imaging . - pubmed
RESULTS : Seventeen concussion patients , ages 9 and 17 ( average = 12.5 years ; median = 13 years , 11 males and 6 females ) , were matched with age and gender controls who had an MRI following a complaint of headache . - pubmed
Glucocorticoid resistance of allogeneic T cells alters the gene expression profile in the inflamed small intestine of mice suffering from acute graft - versus - host disease . - pubmed
The enrolled children diagnosed with ASD were examined by magnetic resonance imaging ( MRI ) and took genetic tests to rule out other neurological and congenital diseases . - pubmed
Patients with ruptured ACL grafts had more medial tibiofemoral compartment OA than those with an intact ACL graft ( p = 0.0003 ) . - pubmed
OA was asymmetric in patients with ruptured ACL grafts with more OA in the medial than in the lateral tibiofemoral compartment ( p = 0.013 ) and the patellofemoral compartment ( p = 0.002 ) . - pubmed
The distribution of OA between compartments was similar in patients with an intact ACL graft . - pubmed
KT-1000 values of anterior knee laxity were higher in patients with ruptured compared to those with intact ACL grafts ( p = 0.012 ) . - pubmed
Side - to - side comparisons of anterior knee laxity showed higher KT-1000 values in patients with ruptured ACL graft ( p = 0.0003 ) and similar results in those with intact graft ( p = 0.09 ) . - pubmed
CONCLUSIONS : Median 31 ( range 28 - 33 ) years after ACL reconstruction , 50 % of the patients showed an intact ACL graft and no side - to - side difference regarding anterior knee laxity . - pubmed
Patients with ruptured ACL grafts had more OA of the medial tibiofemoral compartment than those with intact ACL grafts . - pubmed
Chronic or recurrent forms of somatization lead to heavy emotional and financial burden to the patients and their families . - pubmed
In this study , 18 SFD patients and 21 matched healthy controls were enrolled and underwent an 18F - FDG PET scan . - pubmed
In addition , the Pearson coefficients between the neuropsychological scores and regional brain 18F - FDG uptake values were computed for SFD patients . - pubmed
CONCLUSIONS : In this national analysis , a VATS approach for lobectomy in patients who received induction therapy for locally advanced NSCLC was not associated with worse short - term or long - term outcomes when compared to an open approach . - pubmed
OBJECTIVE : We analyzed the clinical characteristics of patients with isolated epiglottic collapse ( IEC ) who had an epiglottic anteroposterior ( AP ) collapse as the only cause of snoring during drug - induced sleep endoscopy ( DISE ) . - pubmed
CONCLUSION : The clinical characteristics of IEC patients differed from the control group , and IEC could not be identified during awake endoscopy . - pubmed
Oxytocin induced labor causes region and sex - specific transient oligodendrocyte cell death in neonatal mouse brain . - pubmed
This may be an underlying mechanism explaining the human epidemiological data suggesting an association between induced labor and mental disorders . - pubmed
Integration of oral targeted therapies ( OTTs ) in the management of CLL has fundamentally altered CLL treatment pathways and improved outcomes for patients with CLL.We review the cost - effectiveness of OTTs in the treatment of CLL . - pubmed
Infectious diseases are an important cause of human death . - pubmed
The " transcriptome after death " involves the study of mRNA transcripts occurring in human tissues after death ( thanatos , Greek for death ) . - pubmed
Cystic trophoblastic tumor is an uncommon lesion which is occasionally seen after chemotherapy in metastatic retroperitoneal lymph nodes in patients with testicular germ cell tumor . - pubmed
Coronary spastic angina ( CSA ) in premenopausal women is rare , but has also been suggested to be associated with estrogen decline during the menstrual cycle . - pubmed
In this report , we describe the case of a young premenopausal patient with refractory CSA . - pubmed
After the start of this treatment , the patient became completely free of angina episodes . - pubmed
Although there are a few reports of the efficacy of hormone replacement therapy in premenopausal women with CSA , this is the first report of the efficacy of this therapy in a woman as young as 22 years old . - pubmed
< Learning objective : There are a few reports of episodes of CSA occurring in relation to the phase of the menstrual cycle in premenopausal women . - pubmed
Characterization of relapse patterns in patients with acute lymphoblastic leukemia treated with blinatumomab . - pubmed
It is approved for the treatment of patients with relapsed / refractory B - cell acute lymphoblastic leukemia ( B - ALL ) and in patients with minimal residual disease after intensive induction chemotherapy . - pubmed
METHODS : We reviewed patients treated with blinatumomab with relapsed , refractory or minimal residual disease - positive B - ALL from 1 December 2014 to 31 December 2018 at a single academic medical center . - pubmed
Patient demographics , blast percentage prior to blinatumomab initiation , prior lines of therapy , blinatumomab treatment duration , sites of relapse , progression free survival , and overall survival were collected . - pubmed
Four ( 20 % ) patients developed extramedullary relapse following blinatumomab . - pubmed
Background : Median overall survival is 12 to 15 months in patients with metastatic adrenal cortical carcinoma ( ACC ) . - pubmed
These treatments may be attractive to ACC patients with limited other therapeutic options . - pubmed
The study included patients who underwent combined FLACS and AK , with corneal astigmatism ranging from 0.4 to 1.5 diopters ( D ) . - pubmed
Findings : While symptom - triggered therapy through instruments such as the CIWA - Ar protocol has shown to lower total benzodiazepine dosage and treatment duration in patients in alcohol withdrawal , over - reliance on such tools may also lead providers to overlook other causes of delirium . - pubmed
Two of them , HeLa and MCF-7 , are human carcinogenic cells from cervical carcinoma and human breast cancer , respectively . - pubmed
BACKGROUND : Second primary malignancy in patients with papillary thyroid carcinoma after Chernobyl accident is an emerging problem . - pubmed
RESULTS : Secondary primary cancer was detected in 1.8 % ( 119 of 6559 ) of the patients with papillary thyroid carcinoma . - pubmed
CONCLUSION : Patients with papillary thyroid carcinoma after Chernobyl accident are at risk of secondary primary malignancy . - pubmed
Awareness and screening of secondary cancer is needed for patients with papillary thyroid carcinoma after Chernobyl accident . - pubmed
Patients and methods We studied five patients with pancreatic ductal adenocarcinoma ( PDAC ) and one with chronic myelogenous leukemia ( CML ) , who suffered from AOSPD . - pubmed
Prompt diagnosis of AOSPD could avoid shortening of survival of patients with an already poor prognosis by infection . - pubmed
Impact of hypertension on short- and long - term survival of patients who underwent emergency surgery for type A acute aortic dissection . - pubmed
Background : To explore the clinical characteristics and prognosis of patients with hypertension underwent emergency surgery for type A acute aortic dissection ( TA - AAD ) . - pubmed
Methods : The present study enrolled 712 consecutive patients diagnosed with TA - AAD and received aortic repair surgery at our hospital between January 2014 to December 2018 . - pubmed
Patients were grouped by preexisting hypertension history and matched with propensity scores matching method . - pubmed
However , our data suggested that hypertensive patients presented with less intra - operative aortic valve involvement . - pubmed
Case report : A 41 - year - old woman underwent ultrasound ( US ) at 16 weeks , which showed oligohydramnios and intrauterine growth restriction ( IUGR ) . - pubmed
An in vivo experiment with an orthotopic glioma mouse model confirmed the advantages of the proposed methods . - pubmed
Administering D - aldosterone , 7 microgram 100 g-1 , to rats results in a marked rise in ammonium excretion and metabolic alkalosis . - pubmed
Twenty - six patients with metastases from a germinal cancer of the testis were treated with Mithramycin . - pubmed
In cultures of chick embryo fibroblasts infected with Rous sarcoma virus , incubation for a 2 - day period with 1 to 3 mM concentrations of this inhibitor , as late as 4 days after infection , irreversibly prevented subsequent formation of foci of transformed cells . - pubmed
[ Autonomic insufficiency in dialysis patients ] . - pubmed
With the aim of determining the evolution of hypertension associated with PHPT , we analyzed a group of 56 patients followed for a mean of 60 months ( range 10 - 101 months ) after successful parathyroidectomy for PHPT . - pubmed
None of the patients had renal impairment . - pubmed
Two hypertensive patients died during the follow - up from complications related to their hypertension . - pubmed
Twelve ( 21.8 % ) patients were hypertensive before parathyroid surgery ( systolic greater than 160 mmHg and/or diastolic greater than 90 mmHg ) . - pubmed
Pre - operative creatinine clearance was lower in the hypertensive patients than in normotensive patients ( 65.4 + /- 27.5 vs 86.7 + /- 26 ml / min , p = 0.002 ) . - pubmed
During follow - up , none of the patients with pre - operative hypertension became normotensive , whereas 32 % of the patients who were normotensive preoperatively developed clinical hypertension . - pubmed
The patients that developed hypertension after parathyroidectomy were followed for a longer period than the normotensive patients ( 76 + /- 17 vs 53 + /- 10 months , p = 0.005 ) , had a lower postoperative creatinine clearance ( 74 + /- 28 vs 90 + /- 25 mg / min , p = 0.07 ) , and higher cholesterol levels ( 6.2 + /- 1.5 vs 5.5 + /- 0.9 mmol / L , p = 0.08). - pubmed
This study analyzes variation in bone microstructure with respect to gender , age , and body weight in growing macaques to determine whether the pattern of osteonal remodelling in macaques is like that in analogous bones of humans . - pubmed
These data show that variation in bone microstructure occurs independent of gender , age , and body weight in macaques . - pubmed
Moreover , intracortical bone turnover in the macaque femur is much slower than in humans , making them poor models to study the effects of weightlessness , but good models to study low turnover skeletal dysplasias . - pubmed
Antibodies to shiga holotoxin and to two synthetic peptides of the B subunit in sera of patients with Shigella dysenteriae 1 dysentery . - pubmed
Acute- and convalescent - phase sera from 18 Thai patients and convalescent - phase sera from two Israeli patients and one Bangladeshi patient with Shigella dysenteriae 1 ( Shiga ) dysentery were tested by enzyme - linked immunosorbent assay to detect antibodies that bind S. - pubmed
Paired sera from 24 Maryland adults with Shigella flexneri 2a or Shigella sonnei diarrhea served as negative controls . - pubmed
METHODS : All patients with a diagnosis of subaortic stenosis and complete or partial AV canal defect who had one or more Doppler echocardiographic examinations were identified from a computer data bank . - pubmed
RESULTS : Twenty - one patients with both subaortic stenosis and AV canal defect were identified over a 13 - year period . - pubmed
In six patients , serial examinations demonstrated the de novo occurrence of subaortic obstruction over a period of 10 to 87 months . - pubmed
In five patients , progression of known subaortic stenosis was documented over a 10- to 59 - month period . - pubmed
Surgical resection of subaortic stenosis was performed in 16 patients ; the echocardiographic diagnosis was confirmed in 15 of the 16 . - pubmed
Immune deposits in iris biopsy specimens from patients with Fuchs ' heterochromic iridocyclitis . - pubmed
No specific immune deposits were observed in the irises of the patients with Fuchs ' heterochromic iridocyclitis . - pubmed
Diatrizoic acid was found to be useful when applied by insufflation for demonstration of the nasopharynx , trachea and greater bronchi , especially in patients with airway stenosis and low pulmonary reserve . - pubmed
We have performed simultaneous measurements of the DC - magnetoencephalogram ( DC - MEG ) and DC - electrocorticogram ( DC - ECoG ) in rats ( n = 6 ) subjected to 90 s of reversible anoxia . - pubmed
Attempts to protect the ovary from the toxic effects of radiation and chemotherapy are relevant to the management of the young patient with cancer . - pubmed
Comparative gait analysis of two strains of turkey , Meleagris gallopavo . - pubmed
Economic requirements have encouraged farmers to select broad - breasted strains of turkeys ( Meleagris gallopavo ) . - pubmed
We report seven cases of BaCO3 poisoning in one family ; three hospitalized patients displayed classic signs of barium toxicity , and one patient also developed rhabdomyolysis , respiratory failure , and hypophosphatemia . - pubmed
Complications consisted of 17 local haematomas ( 3 % ) and reversible spasm at the puncture site in one patient ( 0.2 % ) . - pubmed
[ Effect of sclerotherapy in patients with bleeding due to portal hypertension ] . - pubmed
The author reports the preliminary results of an unrandomized trial comparing the effect of endoscopic variceal sclerosis , shunt surgery and medical therapy in the management of cirrhotic patients with variceal bleeding , sixty - six patients were studied , among them 23 received sclerosis , 25 shunt surgery and 18 medical therapy . - pubmed
A surgical case of lipoma in the cerebellopontine angle in a 37 - year - old man is reported . - pubmed
The patient 's chief complaints were left hearing disturbance and dizzy spells . - pubmed
To prospectively assess the value of an algorithm in differentiating spontaneous from secondary bacterial peritonitis , we performed serial paracenteses in 43 episodes of ascitic fluid infection ( 28 spontaneous and 15 secondary ) in 40 patients . - pubmed
After 48 h of treatment the concentration of ascitic fluid neutrophils was below the baseline pretreatment value in all episodes of spontaneous peritonitis but in only two thirds of the patients with secondary peritonitis . - pubmed
The optimal time for repeat paracentesis in patients with infected ascites appears to be 48 h after initiation of treatment . - pubmed
We diagnosed nine renal contusions , five subcapsular hematomas , laceration with perirenal hematoma in three cases and we detected extravasation of the contrast in five patients . - pubmed
The study was performed on endoscopic gastric biopsies of the oxyntic mucosa from 49 patients subdivided into the following groups : A ) with histologically normal mucosa and normogastrinemia ( 22 cases ) , B ) with atrophic gastritis and normogastrinemia ( 12 cases ) , C ) with normal mucosa and hypergastrinemia ( Zollinger - Ellison syndrome , retained antrum ) ( 7 cases ) and D ) with atrophic gastritis and hypergastrinemia ( with or without pernicious anemia ) ( 8 cases ) . - pubmed
Adjuvant arthritis in rats is a T - cell dependent " autoimmune " disease with close similarities to several forms of human arthritis . - pubmed
Doxorubicin was further observed in animal models of subconjunctival scars caused by imbedded silk thread for its inhibitory action in vivo . - pubmed
DESIGN : Blind analysis of serum samples , retrospective analysis of clinical data on patients , and prospective follow - up of a subgroup of patients with Wegener granulomatosis . - pubmed
PATIENTS : The study included 277 patients with Wegener granulomatosis ( 222 with biopsy - proven disease ) and 1657 control patients . - pubmed
Prospective follow - up was on 172 patients with Wegener granulomatosis . - pubmed
A comparative study of portal hemodynamics was made in 79 cirrhotics ( 24 cirrhotics with a large spleen greater than or equal to 500 cm3 in volume , 55 cirrhotics with a spleen less than 500 cm3 in volume ) , 22 patients with idiopathic portal hypertension , and 63 healthy adults who served as the control for portal and splenic venous flows . - pubmed
A total of 168 chronic dialysed patients were subjected to echography ; 48 % of them presented aneurysmal alterations of the fistula , with a tendency to increase in proportion to the length of the dialysis period . - pubmed
We report a case of nasolacrimal duct obstruction with histopathology compatible with localized sarcoidosis , in a patient with no evidence of systemic disease . - pubmed
Twenty five healthy people and 25 patients with shoulder pain underwent US control over a 12 - month period : 24 patients with shoulder pain had rotator cuff and / or biceps tendon lesions . - pubmed
[ Effect of combination chemotherapy with adriamycin in elderly non - Hodgkin ' s lymphoma patients ] . - pubmed
The effects of several new specific bradycardic agents , AQ - A39 and AQ - AH 208 , were evaluated in two models of myocardial ischaemia in anesthetized dogs . - pubmed
In the first model , equal bradycardic doses of AQ - AH 208 and propranolol were compared for their effects on coronary collateral blood flow in dogs subjected to an acute coronary artery occlusion . - pubmed
Specific humoral substances produced and secreted by human tumors that cause hypercalcemia have not been identified . - pubmed
Looking for frequency of somnambulism in 3 homogeneous groups of children , a first group of migrainous children , a second group of epileptic children and a third group of normal children , the authors have observed that an antecedent of somnambulism existed in 28 % of migrainous children , when it was found in only 6 % of epileptic children , and in 5 % of normal children . - pubmed
The practical interest to know this association is that somnambulism may be a real clinical marker of migrainous background that should be searched for in every patient presenting with chronic cephalalgia . - pubmed
It is recommended that such data be determined for each type of laser prior to attempting short - pulsed laser internal trabeculotomy in patients with glaucoma . - pubmed
In the fungus Achlya ambisexualis sexual development in the male strain E87 is controlled by the steroid hormone antheridiol . - pubmed
[ Incidence of mycotic infections in patients with acute myeloid leukemia . - pubmed
The highest levels were recorded in active acromegalics , but cured patients also had higher levels than the control group . - pubmed
Urines of osteoarthrotic patients were compared with those of healthy persons and rheumatoid patients . - pubmed
The profile of urinary peptides of patients with mild form of osteoarthrosis differed significantly from that of other groups studied . - pubmed
The results of patients with rheumatoid arthritis were similar to those of patients with activated or severe form of osteoarthrosis . - pubmed
The beneficial effect of loperamide in some children with severe protracted diarrhoea which persisted when nil by mouth , made us suspect that loperamide may have an antisecretory action . - pubmed
Six of 32 patients with a preoperative neurologic deficit demonstrated mild but definite postoperative neurologic improvement . - pubmed
Evidence is presented that hypoperfusion produced by occlusion of major cranial vessels plays an important role in temporary and permanent neurological deficits seen in patients with cerebrovascular disease . - pubmed
Iodine-123 thyroid scintigraphy allows the diagnosis of a functioning retrosternal goiter in a patient with a mediastinal mass . - pubmed
carried out with the aim of surveying 44 patients who had malignant tumours of the ovaries : - one third of the cases had a positive level more than 10 ng per ml ; - the presence and the serial level depend more on the histological nature of the tumour than the stage of its evolution ; - when a serial level has been negative before treatment it has never become positive in in a definite and continuous manner when the tumour progresses . - pubmed
The diagnostic value of Doppler ultrasound evaluation of peripheral vascular disease in diabetic patients is discussed . - pubmed
False diagnosis of myocardial infarction due to an extreme left sided cardiac rotation in two patients . - pubmed
We present two patients with an extremely rare condition : abnormal cardiac levoposition . - pubmed
Long - lasting hypergastrinaemia has been demonstrated to elicit ECL cell proliferation in laboratory animals , inducing ECL cell hyperplasia , dysplasia and ECL cell tumours , i.e. - pubmed
However , in experimental rodents it is believed that hypergastrinaemia is not per se a stimulus capable of inducing ECL cell transformation , a predisposing genetic background being required for tumour development in endocrine organs . - pubmed
In man , long - standing hypergastrinaemia exerts the same proliferative pressure on ECL cells and is associated with hyperplasia with or without dysplastic changes and carcinoid development . - pubmed
For this reason human gastric argyrophilic ECL carcinoids are subdivided into three main groups depending on their clinical background : ( 1 ) gastric carcinoids in patients with chronic atrophic gastritis ; ( 2 ) gastric carcinoids in patients with Zollinger - Ellison and multiple endocrine neoplasia type 1 syndrome ( MEN - ZES ) ; and ( 3 ) solitary , sporadic gastric carcinoids . - pubmed
METHODS : Thirty - six HIV - infected patients were enrolled in the study . - pubmed
All patients completed an allergy questionnaire and physical examination . - pubmed
OBJECTIVE : To determine how multiple risk factors for osteoporotic fractures could be modified by high - intensity strength training exercises in postmenopausal women . - pubmed
The study was undertaken to examine 34 male patients with unstable angina pectoris who underwent coronary angiography ( in the period of instability and at rehospitalization ) and study of protein and lipid parameters in their plasma . - pubmed
Analbuminemia does not significantly influence hepatocarcinogenesis on comparing F344 rats and a congenic line carrying the analbuminemic mutation . - pubmed
Analbuminemic rats differ from Sprague - Dawley rats ( SD ) , their strain of origin , with respect to carcinogenic susceptibility of various organs . - pubmed
Repeated intradermal injection of inactivated BHV-1 antigen elicited neither the virus neutralizing antibody nor positive skin reaction in cattle free from BHV-1 infection . - pubmed
Cattle initially positive by VN and intradermal tests showed steady increase in antibody titre , and some of them developed little or no skin reaction following repeated DTH testing . - pubmed
We have conducted a Phase I trial to determine the maximum tolerated dose of CPT-11 together with a fixed dose of cisplatin in patients with advanced lung cancer , and the dose - limiting toxicities of this combination . - pubmed
All three patients ( all four cycles ) given 90 mg m-2 of CPT-11 experienced grade 3 diarrhea . - pubmed
K - wire fixation of supracondylar humeral fractures in children : results of open reduction via a ventral approach in comparison with closed treatment . - pubmed
The morbidity and functional outcome of K - wire fixation of dislocated supracondylar humeral fractures in children after open reduction through a ventral approach were studied , using the results after closed reduction as a golden standard . - pubmed
Only one out of 11 patients showed mild varus deformity after open reduction , while this slight malalignment occurred in five of 35 patients after closed reduction . - pubmed
It can be concluded that K - wire fixation of dislocated supracondylar fractures in children gives excellent results and that open reduction via a ventral approach is a logical , safe and elegant alternative , if closed reduction fails . - pubmed
Coagulopathy and fibrinolysis following the bite of a hump - nosed viper ( Hypnale hypnale ) . - pubmed
Fluconazole therapy of oropharyngeal candidiasis in a patient with multiple endocrine failure does not correlate with Candida albicans susceptibility to fluconazole in vitro . - pubmed
We report a case of oropharyngeal and oesophageal candidiasis in a 23 - year - old man with endocrinopathy syndrome . - pubmed
The patient was maintained on fluconazole 200 mg daily without relapse . - pubmed
We conclude that fluconazole 400 mg daily is effective against oropharyngeal and oesophageal candidiasis in a patient with endocrinopathy syndrome , despite the infecting Candida albicans strains being resistant to azole antifungals in vitro . - pubmed
In hippocampal neurons cultured from trisomy 16 ( Ts16 ) mice ( a model for Down ' s syndrome ) , the maximum inward conductance mediated by these channels was reduced 47 % relative to control diploid neurons . - pubmed
Effects of novel and conventional anti - cancer agents on human endothelial permeability : influence of tumour secreted factors . - pubmed
Monolayers of human umbilical vein endothelial cells ( HUVEC ) grown on membrane filters were incubated in drug in normal growth medium or medium conditioned by the human melanoma cell line , RPMI-7951 ( TCM ) . - pubmed
The effect of chronic periodontal disease on human jaw muscles : a pilot study using computed tomography . - pubmed
Patients with chronic periodontal disease sometimes complain of difficulty in masticating hard foods . - pubmed
Mutants of Escherichia coli heat - labile enterotoxin as an adjuvant for nasal influenza vaccine . - pubmed
When influenza vaccine was administered intranasally with LT7 K and LT192 G , BALB / c mice developed high levels of serum and local antibodies to the HA molecules . - pubmed
Subcutaneous nodules caused by Pseudomonas aeruginosa without sepsis . - pubmed
Suppurative panniculitis can also be caused by P. - pubmed
METHODS : In our study we included 45 healthy , non pregnant , female controls , 45 healthy pregnant women , and 45 preeclamptic women . - pubmed
Expression of the beta1 subunit by renal glomerular cells was evaluated by biochemical and morphological means in short- and long - term diabetic rats . - pubmed
Western blots of isolated rat renal glomeruli demonstrated that the expression of beta1 increases along with age as well as with the hyperglycaemic state . - pubmed
The methods are illustrated with a dataset consisting of stroke rehabilitation inpatients discharged during a 3 - year period with an admission date that is within 1 year after stroke . - pubmed
As yet , there is no consistently effective method to predict an individual ITP patient 's response to splenectomy . - pubmed
Despite pneumococcal vaccination prior to splenectomy , fatal fulminant sepsis is an omnipresent possibility . - pubmed
METHODS : A retrospective review of 55 women with early - stage breast cancer treated from 1990 to 1995 was performed . - pubmed
PURPOSE : To evaluate intraocular pressure ( IOP ) control after extracapsular cataract extraction ( ECCE ) with posterior chamber intraocular lens ( PCIOL ) implantation in patients with capsular glaucoma ( CG ) and coexisting cataract . - pubmed
METHODS : This prospective study included 20 patients ( 20 eyes ) having CG and cataract whose IOPs were under 22 mm Hg and controlled with antiglaucoma medication . - pubmed
CONCLUSION : The result of our study revealed that ECCE with PCIOL implantation may be a reliable choice in controlling IOP in patients with CG . - pubmed
A total of 17 patients ( 18 feet ) were evaluated following external neurolysis for heel pain caused by entrapment of the first branch of the lateral plantar nerve . - pubmed
[ Listeriosis : an infrequent infection in patients with HIV ] . - pubmed
The patient dead 72 hours later with hepatic encepholopathy . - pubmed
Listeriosis is an infrequent disease in patients with HIV that causes difficult diagnostic problems , principally in patients without prophylaxis with cotrimoxazole for PCP . - pubmed
A case of PCL in a 72 - year - old man with moderate aortic stenosis is presented . - pubmed
The patient was investigated because of pericardial effusion and diagnosis of diffuse large B - cell lymphoma was obtained by open - chest biopsy of the heart . - pubmed
Accelerated recovery after endotoxic challenge in heat shock - pretreated mice . - pubmed
These observations suggest that the mechanism of heat shock - mediated protection ( stress tolerance ) after LPS challenge is due to an increase in the capacity of the organism to recover rather than deterrence from the insult . - pubmed
Acute toxicity of drainage ditch water from a Washington State cranberry - growing region to Daphnia pulex in laboratory bioassays . - pubmed
To determine the toxic effects of multiple pesticides entering the GDD , standardized laboratory toxicity tests with D. - pubmed
Immunomodulatory activity of the aqueous extract from rhizome of Smilax glabra in the later phase of adjuvant - induced arthritis in rats . - pubmed
Our previous paper has reported that the aqueous extract from Rhizoma Smilacis Glabrae ( RSG ) remarkably inhibited the primary inflammation of adjuvant arthritis ( AA ) in rats . - pubmed
METHOD : One hundred and sixty - seven adults suffering from anxiety and/or depression and not receiving any form of psychological treatment or counselling were randomly allocated to receive , with or without medication , BtB or treatment as usual ( TAU ) . - pubmed
RESULTS : Patients who received BtB showed significantly greater improvement in depression and anxiety compared to TAU by the end of treatment ( 2 months ) and to 6 months follow - up . - pubmed
Successful pregnancy outcome in a patient with complete heart block . - pubmed
The classification and diagnosis of human tumors by tissue culture methods . - pubmed
In a prospective study , we analysed 117 patients ( age 17 - 79 years ) who were treated with IVIG for various neurological diseases including chronic inflammatory demyelinating polyneuropathy , diabetic amyotrophy , inclusion body myositis , multiple sclerosis , Guillain - Barre syndrome , Miller - Fisher syndrome , multifocal motor neuropathy , myasthenia gravis and polymyositis . - pubmed
Rash or mild headache occurred in 8 patients , especially when IVIG was given with infusion flow higher than 10 g / h. Two patients showed a severe complication with deep vein thrombosis . - pubmed
Patients with pre - existent disorders like heart or renal insufficiency or immobilised patients , however , may be at higher risk for complications . - pubmed
The effects of growth hormone deficiency and replacement on glucocorticoid exposure in hypopituitary patients on cortisone acetate and hydrocortisone replacement . - pubmed
CONCLUSIONS : Our data suggest that tissue exposure to glucocorticoid is supra - physiological in hypopituitary patients with untreated GH deficiency taking hydrocortisone replacement therapy . - pubmed
We report a case of proliferative myositis in the right biceps of a 56 - year - old man with acquired immune deficiency syndrome ( AIDS ) . - pubmed
We conducted a study to evaluate pharyngeal and palatal functions following reconstruction of soft - palate defects with radial forearm free flaps in 16 patients who had undergone resection of the soft palate for squamous cell carcinoma . - pubmed
Nine patients had partial soft - palate defects and 7 had total defects . - pubmed
In addition , 14 patients had defects of the base of the tongue . - pubmed
One patient developed a transient salivary fistula , which resolved with conservative management . - pubmed
Four patients without dysphagia resumed oral intake 2 weeks after surgery . - pubmed
The 12 patients with dysphagia underwent swallowing therapy . - pubmed
Speech was hypernasal in 2 patients and hyponasal in 3 . - pubmed
Protection against murine endotoxemia by treatment with Ruta chalepensis L. , a plant with anti - inflammatory properties . - pubmed
The anti - inflammatory effect of the extract of Ruta Chalepensis L. ( Rutaceae ) on the course of lethal endotoxemia in BALB / c mice was studied . - pubmed
Pioglitazone prevents hepatic steatosis , fibrosis , and enzyme - altered lesions in rat liver cirrhosis induced by a choline - deficient L - amino acid - defined diet . - pubmed
Non - alcoholic steatohepatitis ( NASH ) may progress to liver cirrhosis , and NASH patients with liver cirrhosis have a risk of development of hepatocellular carcinoma . - pubmed
These results indicate that pioglitazone may be one of the candidates for the benefit drugs for the liver disease of patients with NASH . - pubmed
However , ventricular tachycardias ( VT ) still pose a major problem in a number of cardiac patients . - pubmed
The majority of ventricular arrhythmias , however , are substrate - related reentry tachycardias , most commonly based on an infarct scar Therapy of first choice for these patients is the treatment with an implantable Cardioverter / Defibrillator ( ICD ) . - pubmed
Characterization of a mouse recombination hot spot locus encoding a novel non - protein - coding RNA . - pubmed
Our current knowledge of recombination hot spot activity in mammalian systems implicates a role for both the primary DNA sequence and the nature of the chromatin domain around it . - pubmed
We present a high resolution analysis of a new recombination hot spot in the mouse genome which maps to mouse chromosome 8 C - D. Haplotype diversity analysis across 40 different strains of mice has enabled us to map recombination breakpoints to a 1 - kb interval . - pubmed
It is clear that the development of a safe and effective vaccine for human immunodeficiency virus type 1 ( HIV-1 ) remains a crucial goal for controlling the acquired immunodeficiency syndrome epidemic . - pubmed
Body weight , tail width and food intake , were measured daily and physical activity was measured hourly in normal lean S. - pubmed
The Relationship between chlamydia trachomatis and chlamydia pneumoniae as the cause of neonatal conjunctivitis ( ophthalmia neonatorum ) . - pubmed
Chlamydia trachomatis was confirmed in 20 ( 15.3 % ) using ligase chain reaction and C. - pubmed
This prospective study included 21 patients with N0 or N1 squamous - cell carcinoma of the oral cavity and the oropharynx . - pubmed
The sentinel lymph node was not identified in one patient with recurrence T2N0M0 squamous - cell carcinoma of the oropharynx radiated 3 years earlier . - pubmed
The specificity of the method was 100 % , as was the positive predictive value , because no sentinel node was diagnosed positive wrongly on frozen sections among patients without true histological node metastasis . - pubmed
DISCUSSION : For routine care of patients with squamous - cell carcinoma of the oral cavity and the oropharynx detection of the sentinel lymph node is proposed primarily for patients with T1T2N0 staging . - pubmed
HIV co - infection is associated with reduced HCV treatment response rates and accelerated HCV - related liver disease . - pubmed
Detection of positive - strand HCV RNA was 100 % in both groups ; negative - strand HCV RNA was detected in four ( 33 % ) HCV mono - infected persons and in nine ( 64 % ) HCV / HIV co - infected persons . - pubmed
Esophageal perforation in a patient with metastatic breast cancer to esophagus . - pubmed
We present the case of a patient with esophageal perforation due to dilatation treatments for dysphagia secondary to a distal stricture , later proven to be caused by esophageal metastasis from a breast cancer treated 19 years earlier . - pubmed
MATERIAL AND METHODS : The study group consisted of 438 patients , aged 21 - 46 ( average 29.7 ) , treated because of primary or secondary infertility between January 1999 and March 2003 at Gynecological Endocrinology Department of Medical University of Warsaw . - pubmed
Some species of Babesia cause bovine babesiosis infecting erythrocytes of the cattle and wild ruminants , and undergo a complex developmental cycle in ticks which serve as biological vectors . - pubmed
cause bovine theileriosis infecting lymphocytes as well as erythrocytes of the cattle and wild ruminants , and similar to Babesia undergo a complex developmental cycle in ticks . - pubmed
Today the implantable cardioverter - defibrillator ( ICD ) has become a commonplace therapy around the world for patients with both ischemic and non - ischemic cardiomyopathy and an ejection fraction ( EF ) & lt ; or = 35 % . - pubmed
Can fleas from dogs infected with canine visceral leishmaniasis transfer the infection to other mammals ? - pubmed
In order to investigate the possible role of dog fleas in the transmission of trypanosomatids , ectoparasites were removed from 59 dogs testing positive for canine zoonotic visceral leishmaniasis according to the indirect fluorescent antibody test ( IFAT ) . - pubmed
Sixteen hamsters tested positive for Leishmania infection , 14 on the basis of PCR amplification and four by IFAT assay ( two animals testing positive in both assays ) . - pubmed
chagasi by fleas can not be proven unambiguously even though the hamsters developed infection . - pubmed
In 42 alcoholic inpatients we performed an open randomized study to compare the effects of diazepam and gamma - hydroxybutyrate ( GHB ) on the suppression of severe alcohol withdrawal syndrome and hypercortisolism . - pubmed
[ Changes of toxins and inflammatory mediators in serum after plasma exchange in patients with severe hepatic disease ] . - pubmed
The largest increase ( approximately 318 % ) was attained in mice bearing EAT ascites and receiving 12.5 mg / kg of bromelain . - pubmed
Osteomalacia in a patient with primary intestinal lymphangiectasis ( Waldmann ' s disease ) . - pubmed
We report a case of osteomalacia in a 63 - year - old patient with delayed - onset of PIL , for which she was on dietary treatment . - pubmed
OBJECTIVES : To determine the effectiveness and safety of arthrographic distension of the glenohumeral joint in the treatment of adults with adhesive capsulitis . - pubmed
Safety and efficacy of bivalirudin monotherapy in patients with diabetes mellitus and acute coronary syndromes : a report from the ACUITY ( Acute Catheterization and Urgent Intervention Triage Strategy ) trial . - pubmed
OBJECTIVES : We sought to evaluate clinical outcomes of patients with diabetes mellitus in the ACUITY ( Acute Catheterization and Urgent Intervention Triage Strategy ) trial , overall and by treatment arm . - pubmed
Whether these results apply to patients with diabetes is unknown . - pubmed
RESULTS : Diabetes was present in 3,852 randomized patients ( 27.9 % ) . - pubmed
Compared with nondiabetic patients , diabetic patients had higher 30 - day rates of net adverse clinical outcomes ( 12.9 % vs. 10.6 % ; p & lt ; 0.001 ) , composite ischemia ( 8.7 % vs. 7.2 % ; p = 0.003 ) , and major bleeding ( 5.7 % vs. 4.2 % ; p & lt ; 0.001 ) . - pubmed
CONCLUSIONS : Diabetic patients with ACS managed invasively have higher rates of composite ischemia and major bleeding . - pubmed
Patients with obstetric lacerations were randomized to repair with either blunt or sharp needles . - pubmed
Immunogenicity and reactogenicity of two diphtheria - tetanus - acellular pertussis - hepatitis B - inactivated polio virus - Haemophilus influenzae type b vaccines administered at 3 , 5 and 11 - 12 months of age . - pubmed
The aim of this study was to evaluate the immunogenicity and reactogenicity of two commercial diphtheria - tetanus- acellular pertussis - hepatitis b - inactivated polio virus - Haemophilus influenzae type b ( DTaP - HBV - IPV / Hib ) combination vaccines when administered to infants at 3 , 5 and 11 - 12 months of age . - pubmed
Proteomic analysis of alterations in the secretome of Arabidopsis thaliana suspension cells subjected to nutritional phosphate deficiency . - pubmed
The results indicate that transcriptional control is but one of many factors contributing to Arabidopsis Pi starvation responses , and highlight the importance of parallel biochemical / proteomic studies of -Pi plants . - pubmed
The protective role of alpha - Toc as an antioxidant was evident and it could be used in the treatment of equine ocular diseases in which free radicals are involved . - pubmed
It seems of utmost importance for every physician treating hypertensive patients to become familiar with sexual dysfunction ( through better education and specific seminars ) for the proper management of these patients . - pubmed
METHODS : Data collected from subjects enrolled in the Atropine in the Treatment of Myopia ( ATOM ) study were analysed . - pubmed
Early detection and prevention of CRPCa may provide a new strategy to improve survival of patients diagnosed with PCa at risk to fail standard androgen deprivation therapy ( ADT ) . - pubmed
Pathogenetic factors responsible for the development of the CRPCa phenotype are detectable in the patient 's PCa tissue long before the clinical onset of the disease . - pubmed
Neurodegeneration and prolonged immediate early gene expression throughout cortical areas of the rat brain following acute administration of dizocilpine . - pubmed
Here , we describe the clinical features of a patient who suffered cystic maculopathy during paclitaxel therapy . - pubmed
CASE : A 62 - year - old woman complained of visual disturbances in both eyes after receiving paclitaxel treatment of six months for metastatic breast cancer . - pubmed
CONCLUSION : Paclitaxel treated patients should be followed carefully for ophthalmic complications , especially cystic maculopathy . - pubmed
BACKGROUND : Extensive studies in rodents have identified olfactory ensheathing cells ( OECs ) as promising candidates for cell - based therapies of spinal cord and peripheral nerve injury . - pubmed
During 18 months of follow - up , the primary end point ( composite of all - cause mortality and HF readmission ) occurred in 39 % of the nondepressed patients and 42 % of depressed patients . - pubmed
The effect of the DMP was significantly different in nondepressed than in depressed HF patients . - pubmed
In patients without depressive symptoms , DMP resulted in a trend for lower incidence of the primary end point ( hazard ratio : 0.8 , 95 % confidence interval : 0.61 to 1.04 ) , whereas the reverse was observed in patients with depressive symptoms ( hazard ratio : 1.3 , 95 % confidence interval : 0.95 to 1.98 ) . - pubmed
Prognostic value of initial echocardiographic features in patients with tuberculous pericarditis . - pubmed
We sought to determine initial prognostic factors in patients with TB pericarditis . - pubmed
SUBJECTS AND METHODS : We evaluated initial presentation and clinical outcomes ( mean follow - up 32 + -27 months ) in 60 consecutive patients newly diagnosed with TB pericarditis . - pubmed
RESULTS : Initial presentations were pericardial effusion ( PE ) , effusive - constrictive pericarditis , and constrictive pericarditis in 45 ( 75 % ) , 9 ( 15 % ) , and 6 ( 10 % ) patients , respectively . - pubmed
Of the 54 patients without initial constrictive pericarditis , 32 ( 59 % ) showed echogenic materials in PE , including frond - like exudative coating and fibrinous strands . - pubmed
All patients with effusive - constrictive pericarditis showed echogenic PE . - pubmed
CONCLUSION : Initial pericardial constriction and echogenic PE are poor prognostic signs for persistent pericardial constriction and pericardiectomy in patients with newly diagnosed TB pericarditis . - pubmed
Here we combined MTI with VBM analysis to evaluate extratemporal damage in patients with TLE . - pubmed
MATERIALS AND METHODS : We studied 23 healthy controls and 21 patients with TLE with mean ages , respectively , of 37.6 + - 10.9 and 38.6 + - 9.02 years . - pubmed
Induction of osteoarthritis and metabolic inflammation by a very high - fat diet in mice : effects of short - term exercise . - pubmed
Wheel - running exercise reduced progression of OA in the medial femur of obese mice . - pubmed
CONCLUSION : Obesity induced by a very high - fat diet in mice causes OA and systemic inflammation in proportion to body fat . - pubmed
Mitochondria have been implicated in several human diseases , including cardiac dysfunction , and play a role in the aging process . - pubmed
BACKGROUND : In patients with acute ST - segment elevation myocardial infarction ( STEMI ) , recent clinical guidelines recommend that primary percutaneous coronary intervention ( PCI ) should be performed within 90min of first medical contact or 45min after admission in cathlab . - pubmed
METHODS : From January 2007 to March 2008 , 177 patients were admitted within 12hours of a STEMI in our institution , and 87 were referred for a direct coronary angiography for primary PCI ( 47 by mobile medical emergency unit , 40 by the emergency department of the institution ) . - pubmed
BACKGROUND : Helicobacter pylori are a persistent colonizer of the human gastric mucosa , which can lead to the development of peptic ulcer disease and gastric adenocarcinomas . - pubmed
We describe to our knowledge the sixth case of a papillary thyroid carcinoma within an amyloid goiter , arising in a 45 - year old woman with chronic renal failure due to primary amyloidosis . - pubmed
The patient suffered a total thyroidectomy with the histological diagnosis of amyloid goiter with a multifocal papillary carcinoma of follicular variant . - pubmed
Two years and a half after the surgery the patient is free of recurrence . - pubmed
OBJECTIVE : To evaluate the use of reproductive health care and incidence of paediatric HIV infection during the expansion of antiretroviral therapy and services for the prevention of mother - to - child transmission in rural Malawi , and the influence of integration of these HIV - related services into general health services . - pubmed
Isotopic steady state was achieved within 24 - 48 h. Creatine pool size calculated from urinary D ( 3 )- creatinine enrichment at 72 h significantly increased with muscle accrual in rat growth , significantly decreased with dexamethasone - induced skeletal muscle atrophy , was correlated with lean body mass ( r = 0.9590 ; P & lt ; 0.0001 ) , and corresponded to predicted total muscle mass . - pubmed
PARTICIPANTS : Patients with diabetes aged 18 years or more from the Royal Victorian Eye and Ear Hospital , Victoria , Australia . - pubmed
Korean red ginseng improves blood pressure stability in patients with intradialytic hypotension . - pubmed
According to prehemodialysis blood pressure ( BP ) , 38 patients with IDH were divided into group A ( BP & gt;= 140/90 mmHg , n = 18 ) and group B ( BP & lt ; 140/90 mmHg , n = 20 ) . - pubmed
Chewing KRG renders IDH patients better resistance to acute BP reduction during hemodialysis via activation of vasoconstrictors . - pubmed
This case report describes a diagnosis of right - sided isomerism and specifically right - sided bronchial isomerism in a patient who was being investigated for deteriorating bronchiectasis . - pubmed
Ivemark syndrome ( also known as right atrial isomerism ) combines these associations with malrotation of the gut and a midline liver.2 Interestingly , left - sided isomerism is associated with polysplenia as well as midline liver , malrotation of the gut , partially anomalous pulmonary venous drainage and cardiac septal defects.3 To the best of our knowledge cases of right - sided isomerism are sufficiently rare in adulthood that there are only two other reports in the literature and only one of the patients had bronchial isomerism.4,5 . - pubmed
Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA / H1N1 virus in ferrets . - pubmed
Our findings emphasize the need to prepare for potential pandemics caused by influenza viruses possessing H5 HA , and will help individuals conducting surveillance in regions with circulating H5N1 viruses to recognize key residues that predict the pandemic potential of isolates , which will inform the development , production and distribution of effective countermeasures . - pubmed
A split - root system was applied to analyse the systemic and local response of Arabidopsis thaliana to sulfur starvation . - pubmed
From each of 30 pigs with an infection of L. - pubmed
After 14- day simulated weightlessness for rats , their food - intake and body weight increase were less than those in the control group . - pubmed
A 45 - year - old man who underwent cataract surgery 2 years previously presented with decreased vision in his left eye . - pubmed
Despite this viral escape mechanism , the innate immune system strongly reacts to HCV within the first days after infection . - pubmed
In this review , the available information on how polymorphisms in T2DM - associated genes / loci do directly affect the properties of human islet cells are presented and discussed , including some clinical implications and the role of epigenetic mechanisms . - pubmed
Five species of malaria mosquitoes : An . - pubmed
Among the North Tajikistan malaria mosquitoes , An . - pubmed
Several species of the Lactobacillus genus that are frequently used as probiotics for human consumption merit particular attention because they are increased in the gut microbiota under high - fat diets , are more abundant in obese humans , and are selected by growth - promoter antibiotics ; moreover , the administration of these bacteria in experimental models is linked to the development of obesity . - pubmed
OBJECTIVE : The purpose of this pilot study was to evaluate the effects of extracorporeal shock wave therapy on healing of subcondylar mandibular fracture in rats . - pubmed
METHODS : Unilateral subcondylar fracture in 20 Wistar albino rats was used as a fracture model . - pubmed
CONCLUSIONS : As a result , our study showed that extracorporeal shock wave therapy accelerated the improvement of fractures in experimentally induced subcondylar mandibular fracture in the rat mandible . - pubmed
OBJECTIVE : To evaluate the incidence of subglottic stenosis in children undergoing endotracheal intubation . - pubmed
Children were then classified into two final groups : ' normal final examination ' , with no chronic changes ; and ' subglottic stenosis ' . - pubmed
All the children who developed subglottic stenosis had had moderate to severe alterations immediately after extubation . - pubmed
A 52 - year - old man presented with severe headache and mental deterioration with memory disturbances and bradypsychia . - pubmed
METHODS : A total of 33 consecutive patients ( mean age , 48.0 + - 11.6 years ) with acute Stanford type A aortic dissection who underwent a total arch replacement were included in this study . - pubmed
The causes of mortality were multiorgan failure ( 4 patients ) , renal failure ( 1 patient ) , and postoperative sepsis ( 1 patient ) . - pubmed
Limb ischemia was observed in 4 patients , with all occurring in the lower limb . - pubmed
Postoperative delirium also was observed in 5 patients . - pubmed
Here , we investigated the effects of NOD2 deficiency on cardiac hypertrophy induced by aortic banding ( AB ) in mice . - pubmed
Increased whole blood viscosity associated with arterial stiffness in patients with non - alcoholic fatty liver disease . - pubmed
Therefore , this study aimed to investigate the association of WBV with baPWV in patients with NAFLD . - pubmed
Essentially all cases of cervical cancer , as well as a subset of other anogenital and oral cancers are caused by this limited set of HPV types . - pubmed
RESULTS : In total , 67 % of patients with severe TBI had cognitive impairment . - pubmed
CONCLUSION : Findings highlight cognitive consequences of severe TBI , with nearly two - thirds of patients showing cognitive impairments in at least 1 of 3 cognitive domains . - pubmed
METHODS : Reachable workspaces were obtained from 22 individuals with FSHD and 24 age- and height - matched healthy controls . - pubmed
PATIENTS Y METHODS : One hundred consecutive surgically resected patients with pancreatic ductal adenocarcinoma were included in the study . - pubmed
Determination using synchrotron radiation - based Fourier transform infrared microspectroscopy of putative stem cells in human adenocarcinoma of the intestine : corresponding benign tissue as a template . - pubmed
We obtained tissue sections containing small intestine and colon crypts derived from normal ( benign ) or adenocarcinoma ( AC ) human intestine . - pubmed
Complete transitioning to the radial approach for primary percutaneous coronary intervention : a real - world single - center registry of 1808 consecutive patients with acute ST - elevation myocardial infarction . - pubmed
CONCLUSION : Complete transition from femoral access to a preferred radial access is safe and effective for STEMI patients undergoing PPCI , with a favorable effect on short- and long - term outcomes . - pubmed
This study concluded that MPV , along with several other factors , may be used as a prognostic , independent , and therapeutic marker in patients who are inclined to thrombotic events after cesarean section . - pubmed
Transcranial magnetic stimulation as an antidepressant alternative in a patient with Brugada syndrome and recurrent syncope . - pubmed
After an initial trial of nortriptyline , the patient 's depressive symptoms improved ; however , he experienced a syncopal event and was subsequently diagnosed as having BrS. - pubmed
Given the potential lethality of BrS with known and unknown psychopharmacologic agents , providers should consider TMS as first - line therapy in this patient population . - pubmed
CONCLUSIONS : Patients with pulmonary MAC disease frequently had chronic co - infections with pathogenic microorganisms such as MSSA , P. - pubmed
In our recent work , we identified the structures induced by IBV during infection of cultured cells , as well as primary cells and ex vivo organ culture . - pubmed
We report on the case of a 3 - month - old infant whose continuous biliary obstruction caused by IBS was successfully managed by interventional radiology with the association of N - acetylcysteine and glucagon . - pubmed
Spuriously high platelet counts by various automated hematology analyzers in a patient with disseminated intravascular coagulation . - pubmed
First record of autochthonous canine ehrlichiosis caused by Ehrlichia canis in Romania . - pubmed
This case study describes the first genetically confirmed and clinically manifested autochthonous Ehrlichia canis infection in a 9 - year - old female mixed - breed dog from Romania . - pubmed
This report supports the geographical expansion of canine ehrlichiosis caused by E canis in nonendemic regions of Europe . - pubmed
A TB vaccine should be safe and immunogenic as well as efficacious in all affected populations , including HIV - infected individuals . - pubmed
Psychiatric symptoms in glioma patients : from diagnosis to management . - pubmed
Patients with primary intrinsic brain tumors can experience neurological , cognitive , and psychiatric symptoms that greatly affect daily life . - pubmed
Further research is needed to obtain a better estimate of the prevalence of psychiatric symptoms in glioma patients , and the extent to which these affect everyday functioning and family life . - pubmed
OBJECTIVE : Individuals carrying rare , but biologically informative genetic variants provide a unique opportunity to model major mental illness and inform understanding of disease mechanisms . - pubmed
This included family members with ( n = 7 ) and without ( n = 13 ) the translocation , along with a clinical control sample of patients with psychosis ( n = 34 ) , and a group of healthy controls ( n = 33 ) . - pubmed
Many strategies and methods have been applied to reduce CAUTI ; this article describes a quality improvement ( QI ) approach to the implementation of CAUTI prevention strategies , which can provide better patient experience and outcomes for patients . - pubmed
Understanding how axial loads on the spine influence segmental biomechanics for idiopathic scoliosis patients : A magnetic resonance imaging study . - pubmed
This study investigates the coronal plane segmental biomechanics for adolescent idiopathic scoliosis patients in response to physiologically relevant axial compression . - pubmed
METHODS : Individual spinal joint compliance in the coronal plane was measured for a series of 15 idiopathic scoliosis patients using axially loaded magnetic resonance imaging . - pubmed
Here , four EOCs ( alpha - pinene , 3 - carene , ( + ) - limonene , ( 1S )-(-)- beta - pinene ) were evaluated by disc diffusion assay ( DDA ) and growth inhibition assay ( GIA ) to determine inhibitory effects against five strains of S. - pubmed
PATIENT DESCRIPTION : We describe 14 years of follow - up of an individual with Hoyeraal - Hreidarsson syndrome who initially presented as an infant with intrauterine growth retardation , microcephaly , and central nervous system calcifications . - pubmed
To focus on the 52 patients : median age was 69 years , 65 % were men and 35 % were women , 50 % had haematologic cancers and 50 % had solid tumours . - pubmed
Clinical Reasoning : A 76 - year - old man with acute - onset left - sided weakness and numbness . - pubmed
Letter to the Editor regarding : " Treatment patterns and survival outcomes in patients with cervical cancer complicated by complete uterine prolapse : a systematic review of literature " . - pubmed
This finding correlated with partial rescue of spatial learning and memory impairments in the Morris water maze in comparison to APPSWE / PS1DeltaE9 mice . - pubmed
BACKGROUND : Patients on parenteral nutrition require a central venous access and are at risk of catheter - related thrombosis , pulmonary embolism , and vena cava syndrome . - pubmed
Secondary outcomes were : heparin - induced thrombocytopenia , prevalence of anticoagulation , and quality of International Normalised Ratio management in vitamin K antagonist - treated patients . - pubmed
Given that mitochondrial dysfunction has been identified in fibroblasts , PBMC and brain samples from carriers as well as in animal models of the premutation and that mitochondria are at the center of intermediary metabolism , the aim of the present study was to provide a complete view of the metabolic pattern by uncovering plasma metabolic perturbations in premutation carriers . - pubmed
From the rats that underwent oophorectomy , 10 formed the menopause control group ( Group 2 ) , 10 were administered a daily injection of methylprednisolone until the end of the study ( Group 3 ) , and the remaining 10 rats were administered intraperitoneal streptozocin to induce diabetes mellitus ( Group 4 ) . - pubmed
An 8 - yr - old male golden lion tamarin ( Leontopithecus rosalia ) was diagnosed with diabetes mellitus based on hyperglycemia and persistent glycosuria . - pubmed
Following treatment with exenatide , the persistent glycosuria resolved , the animal maintained normal blood glucose concentrations , and had lower serum fructosamine concentrations compared to pretreatment levels . - pubmed
Gynura procumbens Extract Alleviates Postprandial Hyperglycemia in Diabetic Mice . - pubmed
This study was designed to investigate the inhibitory effect of Gynura procumbens extract against carbohydrate digesting enzymes and its ability to ameliorate postprandial hyperglycemia in streptozotocin ( STZ)-induced diabetic mice . - pubmed
procumbens extract group than in the control group of STZ - induced diabetic mice . - pubmed
procumbens extract administration in STZ - induced diabetic mice . - pubmed
We selected 10 bacteria strains , belonging to Bacillus , Staphylococcus and Serratia genera that are able to produce 3 - hydroxy-2 - butanone ( acetoin ) , a compound with proven growth promoting activity . - pubmed
The BCT9 strain elicited the greatest increases in dry weight and primary root length when L. - pubmed
Magnetic resonance elastography in a rabbit model of liver fibrosis : a 3 - T longitudinal validation for clinical translation . - pubmed
This study aimed to determine the relationships between magnetic resonance elastography ( MRE ) imaging biomarkers and the stages of liver fibrosis in a rabbit model of liver fibrosis , a longitudinal validation for clinical translation . - pubmed
Liver fibrosis was induced in 38 male New Zealand rabbits by weekly subcutaneous injections of 0.1 ml 50 % carbon tetrachloride oily solution per kilogram of body weight for 4 to 10 weeks to produced varying degrees of liver fibrosis . - pubmed
Re - assessing acalculia : Distinguishing spatial and purely arithmetical deficits in right - hemisphere damaged patients . - pubmed
Arithmetical deficits in right - hemisphere damaged patients have been traditionally considered secondary to visuo - spatial impairments , although the exact relationship between the two deficits has rarely been assessed . - pubmed
HIV significantly affects the immunological environment during tuberculosis coinfection , and therefore may influence the selective landscape upon which M. - pubmed
Following a review of the history of human use and scientific study of these drugs , the data from clinical research are summarized , including extensive work on the use of classic hallucinogens in the treatment of alcoholism and other addictions , studies of the use of LSD and psilocybin to relieve distress concerning death , particularly in patients with advanced or terminal cancer , and more limited data concerning the use of classic hallucinogens to treat mood and anxiety disorders . - pubmed
To provide a clinical perspective , case summaries are provided of two individuals who received treatment in recent controlled trials of psilocybin : one being treated for alcoholism , the other suffering from anxiety and depression related to fear of death due to a cancer diagnosis . - pubmed
Glucose levels during hospitalization and incidence of diabetes within 3 years after discharge in patients without diabetes were evaluated . - pubmed
PATIENTS : Fifty - nine patients over the age of 18 with computed tomography scans of the pelvis separated into 2 groups : a group with normal pelvic anatomy and a group with sacral dysmorphism . - pubmed
MATERIALS AND METHODS : Forty - one patients ( mean , 52 years ; range , 18 - 77 years ) with severe brain injuries were studied . - pubmed
BACKGROUND : This systematic review and meta - analysis evaluated the short- and long - term outcomes of liver resection for colorectal liver metastases ( CRLM ) in elderly patients . - pubmed
A man with no history of infection developed cryptococcal meningitis and a right parahilar cryptococcal mass . - pubmed
Cancer cell lines of human tissue origin have been extensively used to investigate antiproliferative activity and toxicity of herbal extracts , isolated compounds , and anticancer drugs . - pubmed
In consequence , three dimensional ( 3D ) human hepatoma cell culture models are being developed as a resource to achieve these goals of simulating the in vivo tumor microenvironment . - pubmed
It is assumed that bioengineered 3D hepatoma cell culture models can provide significant assistance in scrutinizing the molecular response of herbal natural products to recognize novel prognostic targets and crucial biomarkers in treatment strategies for cancer patients in near future . - pubmed
Gene microarray analysis of the circular RNAs expression profile in human gastric cancer . - pubmed
Human gastric cancer is a common malignant neoplasm of the digestive system and represents a threat to human health worldwide . - pubmed
The present study identified circRNAs in the expression profile of human gastric cancer that were potentially involved in the underlying molecular mechanisms of its development . - pubmed
Background : A recent study demonstrated that inflammatory bone markers play a role in the antidepressant functions of ( R , S )- ketamine in treatment - resistant patients with depression . - pubmed
METHODS : We included 1,066 probable AD patients from the Amsterdam Dementia Cohort ( n = 290 ) , Alzheimer ' s Disease Neuroimaging Initiative ( n = 268 ) , Dementia Competence Network ( n = 226 ) , and University of California , San Francisco ( n = 282 ) with available follow - up data . - pubmed
Patients were previously clustered into two subtypes based on their neuropsychological test results : one with most prominent memory impairment ( n = 663 ) and one with most prominent non - memory impairment ( n = 403 ) . - pubmed
CONCLUSIONS : AD patients with most prominently non - memory impairment show faster disease progression and higher risk of mortality than patients with most prominently memory impairment . - pubmed
In humans , recent studies have correlated AGD in boys to testicular anomalies . - pubmed
The aim of this study was to characterize in vitro the effect of autologous cartilage micrografts on chondrocyte viability and differentiation and perform an evaluation of their application in racehorses affected by joint diseases . - pubmed
Preliminary data in the treatment of racehorses are suggestive of a potential in vivo use of micrografts to treat cartilage lesions . - pubmed
Safety and efficacy of weekly versus three - weekly paclitaxel plus platinum neoadjuvant chemotherapy in patients with locally advanced squamous cell head and neck carcinoma : A pilot study . - pubmed
In the present study , we prospectively assessed the safety and efficacy of weekly versus three - weekly paclitaxel plus platinum neoadjuvant chemotherapy in patients with LA - SCCHN . - pubmed
Materials and Methods : We included 50 newly diagnosed patients of LA - SCCHN in the study and randomized them into two groups to receive either low - dose weekly ( 80 mg / sq . - pubmed
Conclusion : Data from our small study suggest that weekly paclitaxel plus platinum neoadjuvant chemotherapy may be superior to the standard every 3 weeks ' administration in terms of safety as well as efficacy in patients with LA - SCCHN . - pubmed
Microbial isolations were made from Rhododendron catawbiense plants showing symptoms of wilt , dieback , and death of shoots obtained from two nurseries in the Latium region in the late summer of 2012 . - pubmed
To the best of our knowledge , this is the first report of Phytophthora damage on Rhododendron caused by P. - pubmed
The selection criteria included randomised controlled trials of the effect of vitamin D supplementation ( 1000 - 4762 IU / day ) on pregnant women with gestational diabetes mellitus . - pubmed
Prior studies show that estrogens and neurogenic factors , including hypothalamic glutamatergic NMDA receptor plasticity , play significant roles in rodent hypertension . - pubmed
Together , these findings reveal that early and late stage AOF female mice display unique molecular signatures of long - lasting synaptic strength prior to , and following hypertension . - pubmed
Twenty - seven infants & lt;= 1 year of age with AS who underwent BAV from 2007 to 2017 were included . - pubmed
Subjects with MPHL or FPHL received single injections of 7.5x106 , 1.5x106 or 3.0x105 DSC cells or a placebo in 4 randomized separate regions on their scalp , and hair densities and diameters were measured until 12 months later . - pubmed
Reveals of New Candidate Active Components in Hemerocallis Radix and Its Anti - Depression Action of Mechanism Based on Network Pharmacology Approach . - pubmed
Therefore , it is inferred that the root of Hemerocallis fulva L. can be used as a therapeutic medicine for depression . - pubmed
BACKGROUND : Despite the increasing knowledge of the etiology of neuropathic pain , this type of chronic pain is resistant to available analgesics in approximately 50 % of patients and therefore is continuously a subject of considerable interest for physiologists , neurologists , medicinal chemists , pharmacologists and others searching for more effective treatment options for this debilitating condition . - pubmed
The patient later passed away due to acute hypoxic respiratory failure . - pubmed
STUDY DESIGN : We performed a retrospective study based on patients with olfactory dysfunction . - pubmed
Case summary : A 50 - year - old woman was referred with a chief complaint of transient chest pain , dyspnoea , and paroxysmal thyroid swelling that usually developed after meals . - pubmed
Then , we discuss our recent studies regarding paternal inheritance of the tumor - augmenting effects in F2 mice by gestational arsenite exposure , in which we investigated alterations of DNA methylation status in F2 tumors and causative F1 sperm . - pubmed
Patients pre - induced with MVI rarely require labour augmentation with oxytocin . - pubmed
Acute normovolemic hemodilution for a patient with secondary polycythemia undergoing aortic valve replacement due to severe aortic stenosis - A case report . - pubmed
Background : A high hematocrit level in patients with erythrocytosis is linked with increased blood viscosity and increased risk of thromboembolism . - pubmed
The preoperative hematocrit level of this patient was very high due to secondary polycythemia by hypoxia . - pubmed
We decided to perform acute normovolemic hemodilution after anesthetic induction to reduce the risk of thromboembolism in the patient . - pubmed
Conclusions : We estimate that patients with secondary polycythemia may benefit from acute normovolemic hemodilution to reduce their hematocrit levels while undergoing cardiac surgery using cardiopulmonary bypass . - pubmed
Studies of humans were included regardless of age , sex , ethnicity , and health status , with the exception of IVD herniation . - pubmed
The best evidence supports traditional ACL reconstruction for the surgical management of patients with documented nonfunctional partial tears of the ACL . - pubmed
METHOD : We collected ( n = 31 ) cord blood samples from atopic mothers and followed up their infants at 4 - 6 and 12 months of age for collection of peripheral venous blood samples and diagnosis of AD . - pubmed
Individual and combined effects of 5 - year exposure to hyperandrogenemia and Western - style diet on metabolism and reproduction in female rhesus macaques . - pubmed
Hyperandrogenemia in the presence of a WSD worsens metabolic function in female nonhuman primates . - pubmed
MAIN RESULTS AND THE ROLE OF CHANCE : After 5 years of treatment , WSD exposure moderately increased body weight and body fat , although control animals also had a high body mass index due to ad libitum feeding . - pubmed
LIMITATIONS , REASONS FOR CAUTION : The small sample size and heterogeneity in metabolic effects observed in the T + WSD group are limitations of the current study , with only a subset of animals in this group showing impaired insulin resistance relative to controls . - pubmed
In addition , obesity in the C group prevented comparisons to lean animals . - pubmed
Paraneoplastic neurologic diseases ( PND ) are rare but can occur in patients with common malignancies including breast cancer . - pubmed
In patients with hormone receptor ( HR )- negative human epidermal growth factor receptor 2 ( HER2 )- positive breast cancer , PND have been reported in association with anti - Yo antibodies and with clinical presentation of paraneoplastic cerebellar degeneration . - pubmed
We describe the case of a woman with progressively altered mental status and seizures , ultimately requiring admission . - pubmed
[ Specific prophylaxis of colibacillosis and salmonellosis in lambs and piglets ] . - pubmed
Eight - year experience in conducting antithrombotic prophylaxis , by methods elaborated by the authors , in 93 patients operated on for acute thrombosis in the system of venae cavae superior and inferior is generalized . - pubmed
Effect of aging in two - stage carcinogenesis on mouse skin with phorbol myristate acetate as promoting agent . - pubmed
Life table analysis curves have been constructed for some of the data presented in a previous report on the effect of aging and of the interval between primary and secondary treatment in two - stage carcinogenesis on mouse skin . - pubmed
In a herd of pigs , 31 % presented serological reactions positive or doubtful to brucellic infection ; in 15 % of the sows the mammary glands were swollen and purulent ; the retromammary ganglions were enlarged and hemorrhagic . - pubmed
Bacteriological examination of the pus of mammary lesions showed the presence of Brucella suis , which confirmed the diagnosis of brucellic mammitis in the sows . - pubmed
Transgenic male M54 were crossed with female CBA / N mice carrying the Xid defect . - pubmed
Ninety - seven consecutive patients who underwent four different types of regional anaesthesia such as lumbar epidural , spinal , caudal and brachial blocks were studied for their incidence of shivering . - pubmed
This self - directed learning module highlights advances in the management of the person with a spinal cord deficit . - pubmed
Traumatic spinal cord injury is being used as the model , but the principles apply to all patients with spinal cord deficits . - pubmed
A basal , highly fortified diet was fed to all pigs at 3 % body weight daily . - pubmed
Treatments consisted of the addition of cassava chips at 0 , 1 , and 2 % of body weight daily . - pubmed
In anesthesized dogs with closed chest and natural respiration massive embolism of pulmonary artery has been simulated with the aid of marked muscular emboli . - pubmed
Identification of virus - specific antigens in cultured cells infected with Marek ' s disease virus serotype 2 and CVI-988 strain . - pubmed
This antigen was not found in cells infected with Md / 5 and JM strains of MDV1 , and the results of kinetic analysis of antigen expression showed this antigen appeared to be related to late membrane antigens . - pubmed
T - cell receptor gene rearrangements and the diagnosis of human T - cell neoplasms . - pubmed
After transurethral resection of the tumour , all patients received a course of radical radiotherapy , with salvage cystectomy for those who failed to respond . - pubmed
Twenty - two of 23 ( 96 % ) patients with tumours that had both these features did not respond to radiotherapy . - pubmed
Nifedipine ( 10 mg tid ) or placebo was administered in a randomized double - blind trial for 1 wk to 2 groups of 10 mildly hypertensive euthyroid patients . - pubmed
We have investigated the possible vascular changes induced by PDT in an intraocular retinoblastoma - like rat tumour model using the 86RbCl extraction procedure . - pubmed
However , in terms of basic investigations of cell and tissue activity in grouped materials of patients with metabolic bone disease and the evaluation of treatment regimens in these materials , bone histomorphometric investigations still yield the most detailed analyses . - pubmed
A depression in aortic contractility has been previously demonstrated in rat intraperitoneal sepsis and during endotoxemia . - pubmed
Calcium influx stimulated by high K + was unchanged in aortae between control and septic animals . - pubmed
In the presence of NE , calcium efflux ( an indirect measurement of intracellular calcium release ) was significantly diminished ( P less than .001 ) in aortae from septic rats . - pubmed
In this study we have investigated the effect of repeated airway challenge with AMP in 10 atopic , subjects without asthma . - pubmed
Intraocular inoculation of herpes simplex virus type 1 ( HSV-1 ) in one eye of rabbits results in encephalitis and contralateral necrotizing viral retinopathy . - pubmed
Ipsilateral retinopathy ( IR ) developed in 83 % of vitreous - inoculated rabbits , but in only 5 % of AC - inoculated animals . - pubmed
We investigated the therapeutic effects of glycine in seven patients with various forms of myoclonus . - pubmed
The control patients included 10 with noninfectious inflammatory diseases and 9 with central nervous system infections . - pubmed
Because of uncertainty about the place of hormones in the treatment of postmenopausal bone loss vertebral and forearm bone loss was measured by absorptiometry in early postmenopausal women before and after continuous or sequential treatment with combined oestrogen and progestogen in a double blind placebo controlled trial . - pubmed
Before a policy of supplementation with hormones can be recommended to all postmenopausal women with the aim of reducing the incidence of vertebral crush fractures further studies with different doses and combinations of hormones , administered over several years , are needed . - pubmed
Aerobic exercise may be helpful in many patients , and administration of tricyclic compounds in very low doses is often effective in treating the associated sleep disorder and in reducing overall disease severity . - pubmed
Pituitary tumors induced by chronic diethylstilbestrol ( DES ) treatment in female F344 rats were treated subsequently with bromocriptine ( BC ) . - pubmed
Two patients are presented with rare aseptic osteonecrosis of the femoral head appearing during the last trimester of pregnancy . - pubmed
Both patients suffered from increasing pain in one hip joint , beginning about one month before parturition . - pubmed
Early shunt thrombosis ( within 72 hours postoperatively ) occurred in 3 patients . - pubmed
Pulmonary artery growth in patients with tetralogy of Fallot was greater than that in patients with single ventricle , and the duration of palliation was acceptable in most patients . - pubmed
The anti - human P component stained positively systemic amyloids and cerebral amyloid plaques of SSE , but failed to stain senile plaques of SDAT . - pubmed
Natural infections in hartebeest , hyaena and lion in the Serengeti National Park , Tanzania . - pubmed
Immune responses to tumour and embryo cells in patients with mammary carcinoma . - pubmed
[ Chronic steatorrhea in children due to a congenital insufficiency of pancreatic lipase ] . - pubmed
IC were seen more frequently in patients with cirrhosis than in CAH patients without cirrhosis and patients with CPH . - pubmed
LSP and LP-2 in IC were detected in 50 % of patients with CAH and , infrequently , in CPH patients . - pubmed
In a group of 56 patients with CAH , followed for two to nine years , those patients treated with steroids showed a tendency to clear IC , whereas no variation was seen in untreated patients . - pubmed
Individuals suffering from the aversive symptoms of that syndrome will be protected from excessive drinking and the related problems . - pubmed
Effect of heart rate on myocardial blood flow in dogs with left ventricular hypertrophy . - pubmed
Because of the previous suggestion that subendocardial perfusion may be inadequate in the hypertrophied heart , this study was carried out to examine the response of transmural myocardial blood flow to pacing induced tachycardia in dogs with chronic left ventricular hypertrophy . - pubmed
Myocardial hypertrophy , produced by banding the ascending aorta of puppies at 5 - 6 wk of age , resulted in an 87 % average increase in relative left ventricular mass compared with the control dogs . - pubmed
Increasing heart rates did not change the transmural pattern of myocardial blood flow in the normal dogs , but in the animals with left ventricular hypertrophy pacing at 250 beats / min resulted in a significant redistribution of perfusion away from the subendocardium , with the ratio of subendocardial / subepicardial blood flow falling from 1.03 + /- 0.08 at 100 beats / min to 0.83 + /0 0.06 at 250 beats / min ( P & lt ; 0.01 ) . - pubmed
Mice continuously infused with the vasopressin fragment des - Gly9 -[ Arg8 ]- vasopressin dicitrate ( DGAVP ) throughout the periods of dependence induction and withdrawal testing exhibited exacerbated withdrawal convulsions . - pubmed
Psychogenic oligodipsia with hypernatremia in a psychotic patient . - pubmed
Acute anterior interosseous neuropathy in a patient with hereditary neuropathy with liability to pressure palsies : a clinical and electromyographic study . - pubmed
Methanolic extract ( CM - ext ) from tubers of Corydalis turtschaninovii forma yanhusuo has been screened for activity in experimental models of types I - IV allergy . - pubmed
In type III allergic model , CM - ext showed the inhibitory effect on direct passive arthus reaction ( DPAR ) in rats . - pubmed
The authors present a case of a 44 year old woman with Ebstein ' s Anomaly of the tricuspid valve . - pubmed
[ Mediastinal abscess diagnosed after its rupture into the trachea in a patient after esophagectomy ] . - pubmed
A 52 - yr - old man with esophageal cancer underwent esophagectomy and retrosternal reconstruction using stomach under general anesthesia . - pubmed
In the postoperative period , the patient developed mediastinal abscess which failed to be diagnosed by daily routine chest X - rays , because of surgical alterations of mediastinal anatomy . - pubmed
On the 11th postoperative day , the abscess ruptured into the trachea and severe hypoxemia ( PaO2 73 mmHg , FIO2 1.0 ) developed while the patient was still on mechanical ventilation . - pubmed
Although surgical drainage was not undertaken , the patient 's severe hypoxemia was resolved within 4 days by the supportive therapies including chest physiotherapy , postural drainage and administration of antibiotics and corticosteroids . - pubmed
The HBM - M cell was originally derived from a patient with mastocytosis . - pubmed
As mastocytosis is thought to represent a reactive hyperplasia rather than a mast cell malignancy , the factor secreted by the HBM - M cell strain could well be responsible for the mast cell hyperplasia seen in some patients with mastocytosis . - pubmed
We estimated the pharmacokinetic characteristics of theophylline in children with bronchial asthma after multiple oral dosing of Theo - Dur , in order to determine whether the absorption of the drug is best described by a zero - order absorption kinetic model ( 0 - order model ) or a first - order absorption kinetic model ( 1 - order model ) . - pubmed
Thirteen children with bronchial asthma were evaluated in this study . - pubmed
METHODS : We studied 33 consecutive patients with lateral medullary infarction who showed appropriate MRI lesions and correlated their clinical findings with the MRI results . - pubmed
CONCLUSIONS : Analysis of MRI findings in rostrocaudal and dorsoventral aspects allows us , although not unequivocally , to make anatomicoclinical correlations in the evaluation of patients with lateral medullary stroke syndrome . - pubmed
We report a case of NMS associated with clozapine as a single agent that developed in a patient with no prior history of NMS . - pubmed
In contrast to other reported cases of NMS with clozapine monotherapy in which rigidity was reported to be absent , our patient had classic NMS with lead - pipe rigidity . - pubmed
NMS should be included in the differential diagnosis of a febrile patient with a history of any neuroleptic treatment , including clozapine . - pubmed
In a randomised , placebo - controlled , double - blind study with parallel group comparison , the efficacy and tolerability of topical treatment with a mucopolysaccharide polysulphate / salicylic acid cream was investigated in 156 patients with acute sprains of the knee or ankle joint . - pubmed
In addition , we observed an inverse correlation between body mass index and obese patients with normal tolerance to glucose . - pubmed
Successful peripheral access was achieved in all patients without bleeding complications . - pubmed
METHOD : Brief Psychiatric Rating Scale ( BPRS ) ratings were obtained in 70 patients with schizophrenia or schizoaffective disorder to determine their response to clozapine compared with a typical neuroleptic . - pubmed
Localisation of the infection was the groin in 70 patients , abdominal aortic prostheses were involved in 16 , crural or extraanatomic prostheses in 13 cases . - pubmed
METHODS : Stool , tumor , and mucosa samples were taken from 25 patients with colorectal adenocarcinoma . - pubmed
Stool and mucosa samples were obtained from 11 healthy patients , and stool , pathologic bowel tissue , and normal mucosa samples were obtained from 3 patients with adenoma ( 1 ) or ulcerative colitis ( 2 ) . - pubmed
Known HPV types have no association with keratoacanthomas . - pubmed
Certain HPV types have been linked to the genesis and development of premalignant and malignant skin diseases . - pubmed
To further study the involvement of HPVs in the aetiology of KAs , we investigated paraffin - embedded specimens of 80 biopsies of KAs for the presence of HPV 1 , 2 , 3 , 4 , 5 , 7 , 26 , 37 , 38 , 47 and 59 DNA by in situ hybridization ( ISH ) with biotinylated probes under high stringency conditions ( Tm-10 degrees C ) . - pubmed
Our results suggest that the known HPV types are unlikely to have any role in the aetiology of KAs . - pubmed
Parainfluenza type 1 ( Sendai ) virus infection in young rats induces airway growth abnormalities associated with persistent pulmonary dysfunction and hyperresponsiveness . - pubmed
The objectives of this study were to compare virus - susceptible brown Norway ( BN ) rats and virus - resistant F344 rats and to determine which of several virus - induced structural abnormalities , including bronchiolar hypoplasia , alveolar dysplasia , bronchiolar mural fibrosis , and increases in bronchiolar mast cells , were associated with virus - induced increases in pulmonary resistance and hyperresponsiveness to methacholine . - pubmed
BN rats infected with virus developed increases in respiratory resistance and hyperresponsiveness that persisted for 28 to 65 d after inoculation . - pubmed
F344 rats were resistant to significant virus - induced alterations in bronchiolar airway wall thickness and mast cell increases as well as to pulmonary function abnormalities . - pubmed
Acute , intravenous systemic toxicity studies have been conducted in sheep and dogs . - pubmed
CONCLUSIONS : Ropivacaine produces sensory and motor blockade which is similar to that produced by equal concentrations of bupivacaine after epidural administration in the sheep . - pubmed
[ Experimental study on the therapeutic effects of SMS201 - 995 on bile - induced acute pancreatitis in the dog ] . - pubmed
We studied the effects of SMS201 - 995 , a long - acting somatostatin analogue , on bile - induced acute pancreatitis in the dog . - pubmed
On the other hand , pancreatic blood flow showed a stronger decrease in SMS - treated dogs than in non - treated ones , and a significant difference was observed at 15 minutes and 1 hour after induction of pancreatitis . - pubmed
Changes in intracellular and extracellular calcium concentration of the myocardial cells during heart failure in children . - pubmed
RESULTS : The concentration of ionized calcium in myocardial cells and the erythrocyte was significantly higher in the patients with heart failure ( 280.85 + /- 47.8 nmol / L , 1.76 + /- 0.04 F335 / F385 ) than in those without heart failure ( 121.88 + /- 13.15 nmol / L , 1.47 + /- 0.08 F335 / F385 ) . - pubmed
Total calcium in the erythrocyte was also increased markedly in the patients with heart failure , but the activity of the erythrocyte membrane pump was lower than in those without heart failure . - pubmed
We studied the magnetic resonance imaging ( MRI ) of 120 knees in 86 rheumatoid arthritis ( RA ) patients and of 14 unaffected knees in 12 control cases . - pubmed
In the second experiment , we confirm these findings with a larger group of five pure alexic patients using a selected subset of high- and low - visual complexity pictures . - pubmed
Wild and mutant strains of Listeria monocytogenes are examined by electron and immunoelectron microscopy . - pubmed
A patient with acute vertigo , and normal findings on neurologic examination , was found to have vertebral artery dissection ( VAD ) . - pubmed
Clinical experience and prospective treatment and outcome studies have demonstrated objective evidence of the efficacy of treating patients with chronic laryngitis symptoms with nocturnal antireflux precautions and acid - suppressing medications . - pubmed
BACKGROUND : Skeletal muscle mass in genetically obese ( ob / ob ) mice displays a reduced mass compared with their normal lean counterpart mice . - pubmed
Force production was unaltered in obese mice . - pubmed
CONCLUSION : Skeletal muscle from obese mice is morphologically and functionally different from lean mouse skeletal muscle . - pubmed
Sixty patients with a hypertensive emergency ( mean arterial pressure & gt;130 mm Hg and evidence of target organ damage ) were randomly divided into two groups of 30 patients each . - pubmed
Mean arterial pressure decreased by 20.1 % : 148.3 + /- 12 to 118.6 + /- 9 mm Hg , p & lt ; 0.002 ; ten patients suffered headache . - pubmed
Three patients in Group A had a subepicardial lesion in the first electrocardiograph , which disappeared with the use of the aerosol . - pubmed
These results seem to indicate that isosorbide dinitrate aerosol is better than tablets for the treatment of patients with a hypertensive emergencies . - pubmed
Further , high T - cell - proliferative- and delayed - type hypersensitivity responses were seen in Peyer 's patch - null mice given oral OVA before systemic challenge . - pubmed
Further , when delayed - type hypersensitivity and splenic T cell proliferative responses were examined , Peyer 's patch - null mice fed TNBS were unresponsive to hapten . - pubmed
A dose of 15 mg / m(2 ) body surface area was given to 14 prepubertal ( median age , 9.4 yr ; range , 6.1 - -10.8 yr ) , 20 pubertal ( median , 13.5 yr ; range , 10.6 - -16.8 yr ) , and 6 postpubertal ( median , 18.2 yr ; range , 17.2 - -20.3 yr ) patients with salt - wasting CAH . - pubmed
MATERIALS AND METHODS : The results are available of prehospital diagnosis of MI in 1500 patients in 1992 - 1996 . - pubmed
A new strain of Bacillus circulans isolated from a larva of Culex quinquefasciatus showed larvicidal activity on 3 mosquitoes of medical importance . - pubmed
The size of the gastric lesions increased gradually after ethanol exposure and was at its greatest after 4 h , in both young and old mice . - pubmed
We performed a randomized study of the effects of the herbal medicine dai - kenchu - to ( DKT ) on 24 patients with PI . - pubmed
In the human hippocampus , magnetic resonance imaging studies have shown that there is a selective atrophy in recurrent depressive illness , accompanied by deficits in memory performance . - pubmed
We studied whether circulating activated platelets and platelet - leukocyte aggregates cause the development of atherosclerotic lesions in apolipoprotein - E - deficient ( Apoe (-/- ) ) mice . - pubmed
Effects of cardiac resynchronization therapy on heart rate variability in patients with chronic systolic heart failure and intraventricular conduction delay . - pubmed
BACKGROUND : A recently discovered DNA virus ( SEN ) has been assumed to be responsible for posttransfusion hepatitis in humans . - pubmed
Phylogenetic analysis of SEN virus has revealed the existence of 8 different strains . - pubmed
Two of them ( SEN virus strain H ( SENV - H ) and SENV - D ) have been described as possible candidate viruses for inducing posttransfusion hepatitis . - pubmed
None of the solely SENV - H - viremic individuals had clinical or biochemical signs of liver disease . - pubmed
Enhanced severity of liver disease could not be observed in patients coinfected with hepatitis C virus and SENV - H. CONCLUSION : We conclude that SENV - H viremia is widespread among hemodialysis patients . - pubmed
Since no viremic patient had clinical or biochemical signs of liver disease , in our setting the hepatitis - inducing capacity of SENV - H remains unclear . - pubmed
Free fatty acids in cerebrospinal fluids from patients with traumatic brain injury . - pubmed
The present study examined FFA concentrations in CSF from 15 patients with traumatic brain injury ( TBI ) and compared the data with values obtained from 73 contemporary controls . - pubmed
Concentrations of specific FFAs from TBI patients , obtained within 48 h of the insult were significantly greater than those in the control group ( arachidonic , docosahexaenoic and myristic , P<0.001 ; oleic , palmitic , P&lt;0.01 ; linoleic , P<0.05 ) . - pubmed
Parasitic infestations in man may cause transient or permanent pulmonary lesions . - pubmed
In this series , transient pulmonary changes were associated with Ascaris lumbricoides , Ankylostoma duodenale , filariasis , Giardia lamblia and Trichinella spiralis ; permanent lesions were produced by Entameba histolytica and Tenia echinococcus . - pubmed
Liposomal amphotericin B , and not amphotericin B deoxycholate , improves survival of diabetic mice infected with Rhizopus oryzae . - pubmed
The efficacies of liposomal amphotericin B ( LAmB ) and amphotericin B deoxycholate ( AmB ) were compared in a diabetic murine model of hematogenously disseminated Rhizopus oryzae infection . - pubmed
These data indicate that high - dose LAmB is more effective than AmB in treating murine disseminated zygomycosis . - pubmed
CLINICAL PRESENTATION : A 48 - year - old man presented with an acute onset of right visual deterioration after an episode of severe headache . - pubmed
CONCLUSION : Although there was no direct evidence of subarachnoid hemorrhage on imaging scans or with operative exploration , we think that the patient must have experienced sentinel hemorrhaging , leading to visual deterioration . - pubmed
Numerous halogenated disinfection by - products ( DBPs ) occur and chronic ingestion has been associated with an increased risk for colorectal cancer in human populations . - pubmed
[ Biological tests for diagnosis of infections in artificial insemination of cattle ] . - pubmed
METHODS : Thirty women with clinical symptoms of vulvovaginal candidiasis ( 15 positive vaginal culture to C. - pubmed
The objective of this review is to juxtapose the therapeutic potential of high and low concentrations of ethanol in the treatment of HCC , based on experimental studies obtained with the human hepatocellular tumor cell line ( HepG2 ) . - pubmed
BACKGROUND : Measuring the circumference of the abdomen is still commonly used when treating a patient with suspicion of intra - abdominal bleeding . - pubmed
METHODS : The study group consisted of 34 end - stage renal failure ( ERSF ) patients treated with peritoneal dialysis . - pubmed
Evaluation of safety and efficacy of gefitinib ( ' iressa ' , zd1839 ) as monotherapy in a series of Chinese patients with advanced non - small - cell lung cancer : experience from a compassionate - use programme . - pubmed
CONCLUSION : Gefitinib demonstrated safety and efficacy as monotherapy in this series of Chinese patients with advanced NSCLC and was also associated with remarkable symptom relief and improvement in QoL. - pubmed
Arsenic compounds , which are well - documented human carcinogens , are now used in cancer therapy . - pubmed
[ Specific developmental disorders in children ] . - pubmed
Long - term follow - up CT scan evaluation in patients with pulmonary sarcoidosis . - pubmed
OBJECTIVES : The aim of the present study was to determine how the pattern and extent of sarcoidosis changes over time on serial high - resolution CT ( HRCT ) scans and to identify CT scan findings that might be helpful in predicting the prognosis of patients with the disease . - pubmed
METHODS : The initial and last HRCT scan findings of 40 patients with pulmonary sarcoidosis during a mean follow - up period of 7.4 years ( range , 3 to 18 years ) were evaluated retrospectively . - pubmed
The predominant patterns seen on the initial HRCT scan may be helpful in predicting the outcomes of patients with sarcoidosis . - pubmed
The aim of this work was to investigate the interactions of tumor cells with dendritic cells ( DC ) in normal donors and patients with multiple myeloma ( MM ) . - pubmed
We reviewed our experiences with the management of sixteen pediatric cases ( 10 males , 6 females ; 11 - days to 14 - years old ) of chylothorax and chylopericardium from 1997 to 2003 . - pubmed
Of the fifteen cases occurring after cardiothoracic surgery , thirteen patients had corrective or palliative surgery for complex congenital heart disease , and two patients had removal of thymolipoma and neuroblastoma , respectively . - pubmed
Included also in this review was an 11 - day old preterm infant with hydrops fetalis and congenital heart disease who developed chylothorax . - pubmed
The recently completed ACTION ( A Coronary Disease Trial Investigating Outcome with Nifedipine GITS ) trial provides further evidence that nifedipine GITS can be used safely in high - risk patients to treat angina , lower blood pressure and significantly improve clinical outcomes . - pubmed
We observed both significant inhibition of tumour growth and extended survival of treated mice . - pubmed
Male - mediated developmental toxicity in mice after 8 weeks'exposure to low doses of X - rays . - pubmed
PURPOSE : The aim of the study was to investigate the effects of subchronic irradiation of male mice on reproduction ability and induction of male - mediated teratogenesis . - pubmed
The case of a bilateral total knee arthroplasty in a hemophiliac patient is presented below . - pubmed
The authors emphasize the importance of the adequate hematological and anaesthetical background when performing surgery in a hemophiliac patient . - pubmed
SUBJECTS : Fifty - seven patients with afebrile seizures fulfilling all of the following criteria were enrolled : ( 1 ) normal development prior to the onset , ( 2 ) no underlying disorders nor neurological abnormalities , ( 3 ) onset before the age of four and ( 4 ) normal interictal EEG and neuroimaging findings . - pubmed
RESULTS : Thirty - nine cases ( Group A ) were characterized by an association of mild gastroenteritis . - pubmed
The remaining 18 cases were divided into two groups according to the seizure type . - pubmed
METHODS : Supine intravenous contrast - enhanced CTC with colonoscopic and/or surgical correlation was performed on 25 patients with colonic adenomas or carcinomas . - pubmed
PARTICIPANTS : Six patients were enrolled : five had symptomatic recurrent or residual WHO Grade I meningiomas and one had an unoperated anterior clinoidal meningioma . - pubmed
One patient was withdrawn from the study because of myelosuppression and underwent further surgery . - pubmed
CONCLUSIONS : From this small pilot study we conclude that although hydroxyurea may be associated with disease stabilization in some patients , it did not reduce tumor mass and it caused significant side effects in some of our subjects . - pubmed
Phase I / II study of bortezomib plus docetaxel in patients with advanced androgen - independent prostate cancer . - pubmed
Lindane toxicity in pigeons . - pubmed
The anti - thrombotic active constituents from Centella asiatica . - pubmed
The in vitro effects of a methanol extract from the aerial parts of Centella asiatica on shear - induced platelet activation and coagulation were assessed after oral administration to rats , by subjecting non - anticoagulated blood to haemostatometry . - pubmed
In spite of the long duration of this cutaneous marker of internal malignancy , the patient was completely asymptomatic and extensive investigations revealed the presence of widespread metastasis of mucin secreting signet cell adenocarcinoma from an unknown primary site . - pubmed
In addition the patient also had acquired hypertrichosis lanuginose and florid cutaneous papillomatosis which are also markers of internal malignancy . - pubmed
Children indicated as tic - positive by the screening procedure were investigated using semi - structured questionnaires and the Polish version of YGTSS scale . - pubmed
Abnormality of the hepatic vein waveforms in cirrhotic patients with portal hypertension and its prognostic implications . - pubmed
CONCLUSIONS : Analyzing the HV waveforms was thus found to be a simple method for accurately assessing the prognosis in cirrhotic patients with portal hypertension . - pubmed
METHODS AND RESULTS : Sixteen male Wistar rats were randomly divided into two groups : normal control and diabetic rats . - pubmed
Diabetes mellitus was induced in rats by streptozotocin injection . - pubmed
At 4 weeks diabetic rats were associated with a lower body weight ( BW ) and heart weight ( HW ) but a higher HW / BW . - pubmed
We hypothesized that in cancer patients with respiratory insufficiency , systemic hypoxemia may be related to enhanced aggressiveness of cancer on one side and to the elevation of angiogenic factors on the other . - pubmed
RESULTS : Patients with systemic hypoxemia had higher incidence rates of locally advanced tumors . - pubmed
Partial oxygen pressure and blood oxygen saturation were significantly lowered in patients with T4 cancers as compared to less advanced ones . - pubmed
Benzene , a carcinogen that can cause cancer in humans , may form at nanogram per gram levels in some beverages containing both benzoate salts and ascorbic or erythorbic acids . - pubmed
Testicular germ cell carcinoma ( TGCC ) is the most common malignancy among men ages 20 to 34 years . - pubmed
Implant - supported overdenture in an elderly patient with Huntington ' s disease . - pubmed
The present paper reports on a patient with Huntington ' s disease who was rehabilitated with a mandibular overdenture supported by two endosteal implants . - pubmed
To reduce the Legionella - linked risk in the several sites of Sud - Francilien Hospital , following a hospital - acquired legionellosis case , a multidisciplinary working group performed an action plan monitored through Legionella pneumophila counts in hot water supply . - pubmed
Similar results were observed for three of the four establishments , whereas the last did not describe a pronounced reduction of Legionella pneumophila counts and showed constantly serogroup 1 strains . - pubmed
OBJECTIVE : To assess the electroanalgesia as an effective method in the reduction of pain and consequent improvement in lung function in patients undergoing coronary artery bypass graft surgery . - pubmed
METHODS : During the period of one year were studied 30 patients undergoing surgery for treatment of the ischemic coronary disease . - pubmed
CONCLUSION : The group that did electroanalgesia presented reduction in the intensity of postoperative pain , which however did not mean improvement in respiratory function of these patients . - pubmed
The authors also suggest methods to increase efficacy and safety of levodopa therapy in patients with Parkinson ' s disease . - pubmed
[ Effects of beta - elemene on proliferation and apoptosis of human multiple myeloma cell RPMI-8226 ] . - pubmed
This study was aimed to investigate the effect of beta - elemene on proliferation and apoptosis of human multiple myeloma cell line RPMI-8226 and its mechanism . - pubmed
The effect of beta - elemene on the growth of human multiple myeloma cell line RPMI-8226 was detected by MTT . - pubmed
Genetic relationships between resistances to Fusarium head blight and crown rot in bread wheat ( Triticum aestivum L. ) . - pubmed
A review was done with 25 scientific papers published in the past fifteen years with the objective to verify the effects of spray dried plasma added to diets for pigs weaned at different ages on the feed intake , weight gain , intestinal structure , and number of E. - pubmed
Beneficial effects of spray dried plasma were observed during the first week after weaning for weight gain and feed intake of piglets weaned at 14 , 21 , and 28 days old . - pubmed
Here we study the bleb - based motions of Entamoeba histolytica in the constrained geometry of a micropipette . - pubmed
BACKGROUND : A retrospective cohort study was performed in 1063 women diagnosed with cervical intraepithelial neoplasia grade 3 ( CIN3 ) ( previously termed carcinoma in situ- CIS ) in the National Women 's Hospital , Auckland , New Zealand . - pubmed
Evaluation of prognosis in patients with respiratory failure requiring venovenous extracorporeal membrane oxygenation ( ECMO ) . - pubmed
PURPOSE : In this study , we analyzed the respiratory status and the prognosis of patients , including adults with acute respiratory failure requiring venovenous extracorporeal membrane oxygenation ( VV ECMO ) to maintain respiratory status . - pubmed
Its biosynthetic gene clusters have been identified in several Streptomyces hygroscopicus strains , and a number of genes within the clusters have been functionally analyzed . - pubmed
Arrhythmia occured in 12 patients , atelectasis in 6 patient and pneumonia in 5 patients . - pubmed
The FDA has approved Fortesta ( Endo ) , a topical gel , for testosterone replacement therapy in adult males with hypogonadism . - pubmed
METHODS : Biopsies were obtained 20 cm proximal to the anus from individuals with quiescent UC and from normal controls . - pubmed
Some of these compounds , such as N -( 2 - diethylaminoethyl )- 4 -[( 123 ) I ] iodobenzamide ( [ ( 123 ) I ] BZA ) and [ ( 123 ) I ]- N -( 2 - diethylaminoethyl )- 2 - iodobenzamide ( [ ( 123 ) I ] BZA2 ) , have been successfully evaluated in melanoma patients , showing high sensitivity and selectivity in the detection of melanoma and its metastasis ( 6 - 9 ) . - pubmed
Spermidine BZA derivatives exhibit high affinity for melanin comparable to that of [ ( 123 ) I ] BZA ; however , these compounds exhibit less accumulation in tumors than [ ( 123 ) I ] BZA in animal models of melanoma ( 13 ) . - pubmed
METHODS : Volunteers with or without schistosomiasis were recruited and divided into a case group and a control group . - pubmed
RESULTS : Two hundred and fifty - three volunteers diagnosed with chronic or advanced schistosomiasis in the case group showed different degrees of gastric mucosal changes , including 7 cases with schistosomal eggs deposited beneath the gastric mucosa ( with an incidence of 2.77 % ) , 33 cases with dysplastic hyperplasia and intestinal metaplasia ( with an incidence of precancerous lesion of 13.04 % ) , and 1 case with gastric cancer . - pubmed
RESULTS : The final sample included 47,153 patients with traumatic spinal cord injury . - pubmed
RESULTS : In the patients with congenital tracheal stenosis , the pressure drop from the tracheal inlet to outlet , at flow rate 3L / min , ranged from 14 to 430 Pa ; the pressure drop at flow rate 7.3L / min ranged from 60 to 1825 Pa. - pubmed
CONCLUSIONS : Simulations with computational fluid dynamics may provide an objective method to evaluate the severity of the symptoms in patients with congenital tracheal stenosis and may help guide treatment . - pubmed
BACKGROUND : The purpose of this study was to assess select medication utilization prior to duloxetine initiation among patients with major depressive disorder , generalized anxiety disorder , diabetic peripheral neuropathic pain , fibromyalgia , and musculoskeletal pain associated with osteoarthritis or low back pain . - pubmed
Using this method we have analyzed 132 controls and 130 Coronary Heart Disease ( CHD ) patients for plasma total homocysteine , wherein , the mean plasma total homocysteine levels were 10.51 + -8.36 and 11.51 + -10.06 mumol / L respectively . - pubmed
Beneficiaries who had 4 years of observation with no timolol use were categorized as " controls " and those with 2 years of non - timolol glaucoma medication use followed by consecutive years of adjunctive timolol use were considered " cases . " - pubmed
Beneficiaries with 2 years of non - timolol glaucoma medication use followed by 1 year in which they used timolol adjunctively and then a year without timolol use were considered " discontinuers . " - pubmed
RESULTS : There were 24,271 glaucoma patients who did not receive timolol ( controls ) , 1,406 beneficiaries who were prescribed timolol in addition to other glaucoma medications and continued its use ( cases ) , and 299 beneficiaries who used adjunctive timolol for only a single year ( discontinuers ) . - pubmed
Localization of pandemic 2009 H1N1 influenza A virus RNA in lung and lymph nodes of fatal influenza cases by in situ hybridization : new insights on virus replication and pathogenesis . - pubmed
STUDY DESIGN : Formalin - fixed , paraffin embedded autopsy tissues from 21 patients with confirmed pH1N1 infection were analyzed by influenza A IHC and by in situ hybridization ( ISH ) using DIG - labeled sense ( detects viral RNA ) and antisense probes ( detects positive - stranded mRNA and cRNA ) targeting the nucleoprotein gene of pH1N1 virus . - pubmed
BACKGROUND : Development of a protective vaccine against human immunodeficiency virus type 1 ( HIV-1 ) is an important subject in the field of medical sciences ; however , it has not yet been achieved . - pubmed
Porphyromonas gingivalis is one of the oral microorganisms associated with human chronic periodontitis . - pubmed
Effects of co - administration of candesartan with pioglitazone on inflammatory parameters in hypertensive patients with type 2 diabetes mellitus : a preliminary report . - pubmed
METHODS : Medical records of gastroparesis patients were evaluated for physician management choices . - pubmed
Seventy - one patients who had undergone megaprosthesis reconstruction for previously unoperated localized lower - extremity osteosarcoma were reviewed . - pubmed
No patient had evidence of infection preoperatively . - pubmed
Fevers ( body temperature of 38 C or higher ) were present in 62 patients ( 87.3 % ) at some point during the first 2 postoperative weeks . - pubmed
Of the 62 febrile patients , 94 % were relieved of fever by postoperative day 5 . - pubmed
Body temperature curves in patients with infection showed that several atypical patterns , such as multiple fever peaks and persistent fever , were accompanied by physical findings within the normalization period . - pubmed
The effect of physiotherapy in addition to testosterone replacement therapy on the efficiency of the motor system in men with hypogonadism . - pubmed
BACKGROUND AND OBJECTIVE : The aim of this study was to analyze whether the addition of physiotherapy to testosterone replacement therapy provides added benefit in improving functional capacity of the motor system in men with hypogonadism . - pubmed
MATERIAL AND METHODS : The study involved 3 groups of subjects : group 1 , healthy men ( n=20 ) ; group 2 , men with hypogonadism who underwent testosterone replacement therapy with physiotherapy ( TRT+PT ) ( n=8 ) ; and group 3 , men with hypogonadism who underwent testosterone replacement therapy alone ( TRT ) ( n=10 ) . - pubmed
CONCLUSIONS : Our results suggest that the application of testosterone replacement therapy together with physiotherapy ( 1 hour twice weekly ) in men with hypogonadism may lead to earlier and better results in comparison with testosterone replacement therapy applied alone . - pubmed
Ninety - two per cent of the influenza A viruses were pandemic A(H1N1 ) 2009 , and following antigenic analysis all of these were found to be similar to the current vaccine strain . - pubmed
Anti - fatigue effect of ginsenoside Rb1 on postoperative fatigue syndrome induced by major small intestinal resection in rat . - pubmed
Ginsenoside Rb1 ( GRb1 ) , one of the principle active ingredients of Panax ginseng , exerts multiple pharmacological activities to fight fatigue . - pubmed
In the present study , we investigate the anti - fatigue effect of GRb1 on postoperative fatigue syndrome ( POFS ) in a rat model induced by major small intestinal resection . - pubmed
Patients with FTLD ( n = 13 ) or AD ( n = 13 ) and healthy controls ( n = 26 ) underwent a neuropsychological assessment and the socioemotional battery ( an empathy questionnaire , an emotion recognition task , and theory of mind tasks ) . - pubmed
Mice underwent permanent middle cerebral artery occlusion ( MCAO ) and were treated with one of the two cooling paradigms : one where cooling ( 30 C ) began at the onset of MCAO ( early hypothermia [ eHT ] ) and another where cooling began 1 hour later ( delayed hypothermia [ dHT ] ) . - pubmed
We studied the genotoxicity of the commonly used OP pesticides chlorpyrifos ( CPF ) , methyl parathion ( MPT ) , and malathion ( MLT ) , individually and in combination , in Wistar rat peripheral blood lymphocytes in vitro . - pubmed
A 55 - year - old woman with a past medical history of methotrexate - controlled RA presented with right leg pain for 4 days . - pubmed
Progressive edema , pain , and neuromuscular deficits persisted despite steroid and antibiotic therapy , so the patient was taken for urgent fasciotomy for acute compartment syndrome . - pubmed
Clinicians should be aware of this uncommon manifestation of RA keeping the various presentations of rheumatoid disease in mind when faced with these patients . - pubmed
METHODS : Data accruing prospectively from January , 2002 to September , 2013 yielded 53 SCA aneurysms in 53 patients . - pubmed
Adult T cell leukaemia / lymphoma ( ATLL ) is a rare T lymphoproliferative disorder which is etiologically linked with human T cell lymphotropic virus type-1 ( HTLV-1 ) . - pubmed
PATIENTS AND METHODS : A total of 102 patients with a clinical diagnosis of AA were admitted during the study period . - pubmed
All the eligible patients who finally diagnosed clinically as having AA were planned for emergency open appendectomy . - pubmed
On histopathology normal appendix was found in nine patients ( 8.9 % ) , AA in 71 patients ( 69.6 % ) , complicated appendicitis ( CA ) which includes perforated and gangrenous appendicitis was present in 22 patients ( 21.5 % ) . - pubmed
& gt;60 % patients presented with CA when the duration of pain was & gt;72 h. Presence of appendicolith increased the probability of CA . - pubmed
These new findings suggest that replacement of defective cells in the inner ear of hearing impaired patients using adult spiral ganglion neurons may offer potential hope to improve the quality of life for patients with auditory dysfunction and impaired hearing disorders . - pubmed
Treatment for individuals with documented ASCVD or at high risk of developing ASCVD begins with lifestyle changes ( adherence to a heart - healthy diet , exercise , tobacco avoidance , maintenance of a healthy weight ) and may also include statin , fibrate , high - dose fish oil , and/or niacin therapy . - pubmed
To delineate the characteristics of this epileptic network , we collected EEG / fMRI data from 23 patients with frontal lobe epilepsy . - pubmed
For each patient , EEG / fMRI analysis was first performed to determine the BOLD response to epileptic spikes . - pubmed
Nine features were used to evaluate the differences of epileptic network patterns in three connection levels between patients and controls . - pubmed
DISCUSSION : The reported cases are explicative as they occurred in patients suffering from different types of cancer and with different causes of BTcP. - pubmed
[ Governance of HIV / AIDS organizations in Bobo - Dioulasso ( Burkina Faso ) ] . - pubmed
In populations with low vaccine coverage , the live - attenuated Sabin strains , OPV types 1 , 2 and 3 , can evolve into virulent vaccine - derived polioviruses ( VDPVs ) and circulate in the community . - pubmed
OBJECTIVES : This study aimed to characterize virus isolates from four AFP patients infected with cVDPV2 in the Extreme North region of Cameroon in 2013 . - pubmed
RESULTS : All four patients were infected by cVDPV2 strains showing 1.2 - 2.0 % nucleotide difference compared to the reference Sabin 2 VP1 sequence . - pubmed
Phylogenetic analysis indicated that the VDPV strains were genetically linked to cVDPV2 lineages of the recent Chad cVDPV2 outbreak . - pubmed
Pincer morphology could be assessed in 18 patients , with coxa profunda in 14 ( 78 % ) and acetabular retroversion in 6 ( 14 % ) . - pubmed
Features of combined pincer and cam impingement were observed in 4 patients ( 17 % ) . - pubmed
Trichoscopic features of frontal fibrosing alopecia : results in 249 patients . - pubmed
The rabbits showed no signs of postoperative inflammation and infection . - pubmed
MATERIALS AND METHODS : Twenty male Wistar rats were subjected to a midline laparotomy and a standard peritoneal and cecum abrasion trauma . - pubmed
OBJECTIVE : To determine the accuracy of BISAP score in finding out the frequency of severity and mortality in patients with acute pancreatitis by comparing it with Ranson 's score . - pubmed
METHODOLOGY : Atotal of 80 patients who presented in emergency with acute pancreatitis were included by consecutive non probability sampling technique . - pubmed
CONCLUSION : The newly proposed BISAP score is a simple and accurate tool for severity stratification and is equally effective in finding out frequency of severity and in turns mortality in patients with acute pancreatitis as Ranson 's score . - pubmed
We aimed to identify simple ultrasound parameters for the screening of patients with unknown significant chronic liver disease . - pubmed
METHODS : Three hundred and twenty seven patients with chronic liver disease , liver biopsy , and ultrasound examination were included in the derivation set . - pubmed
283 consecutive patients referred for ultrasound examination were included in the validation set ; those selected according to the ultrasound parameters identified in the derivation set were then referred for specialized consultation including non - invasive fibrosis tests and ultimately liver biopsy if liver fibrosis was suspected . - pubmed
CONCLUSION : The generalized search of three simple ultrasound signs in patients referred for abdominal ultrasound examination may be an easy way to detect those with silent but significant chronic liver disease . - pubmed
Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes . - pubmed
Treatment of women who remain at risk of preterm birth seven or more days after an initial course of prenatal corticosteroids with repeat dose(s ) , compared with no repeat corticosteroid treatment , reduced the risk of their infants experiencing the primary outcomes respiratory distress syndrome ( risk ratio ( RR ) 0.83 , 95 % confidence interval ( CI ) 0.75 to 0.91 , eight trials , 3206 infants , number needed to treat to benefit ( NNTB ) 17 , 95 % CI 11 to 32 ) and serious infant outcome ( RR 0.84 , 95 % CI 0.75 to 0.94 , seven trials , 5094 infants , NNTB 30 , 95 % CI 19 to 79).Treatment with repeat dose(s ) of corticosteroid was associated with a reduction in mean birthweight ( mean difference ( MD ) -75.79 g , 95 % CI -117.63 to -33.96 , nine trials , 5626 infants ) . - pubmed
CONCLUSIONS : We found a novel anti - inflammatory function of horsefly - derived cecropin - TY1 peptide , laying groundwork for better understanding the ectoparasite - host interaction of horsefly with host and highlighting its potency in anti - inflammatory therapy for sepsis and endotoxin shock caused by Gram - negative bacterial infections . - pubmed
Melanotic neuroectodermal tumour of infancy ( MNTI ) is a rare , benign but locally aggressive neoplasm of infants commonly affecting the maxilla . - pubmed
This Review outlines recent advances in the understanding of immunopathology , vaccine development and human monoclonal antibodies produced against dengue virus . - pubmed
Expert consensus on the perioperative management of patients with sepsis . - pubmed
While the dosage of many general anti - tumor drugs is adjusted according to the patient body surface area , one uniform dose of most TKIs is recommended regardless of body size . - pubmed
The aim of this prospective controlled study was to investigate the levels of reactive oxygen species ( ROS ) , including asymmetric dimethylarginine ( ADMA ) , oxidative stress index ( OSI ) and total oxidant capacity ( TOC ) , and antioxidants with total antioxidant capacity ( TAC ) in peripheral and internal spermatic veins blood , the relationship of these factors with sperm parameters in the infertile varicocoele patients , and the amelioration effect of varicocoelectomy on these outcomes . - pubmed
BACKGROUND : Liver fibrosis progresses faster in individuals coinfected with human immunodeficiency virus ( HIV ) and hepatitis C virus ( HCV ) . - pubmed
We present the case of a 5 - year - old boy who developed a delayed onset intractable hyperventilation following endoscopic third ventriculostomy . - pubmed
METHODS AND MATERIALS : Using the 1998 to 2011 National Cancer Data Base , we identified 8273 women who underwent mastectomy for nonmetastatic IBC . - pubmed
Evaluation of kinematics and injuries to restrained occupants in far - side crashes using full - scale vehicle and human body models . - pubmed
Panaxatriol saponins promotes angiogenesis and enhances cerebral perfusion after ischemic stroke in rats . - pubmed
BACKGROUND : Panaxatriol saponins ( PTS ) , an extract from the traditional Chinese herb Panax notoginseng , which has been used to treat ischemic stroke for many years in China . - pubmed
METHODS : Middle cerebral artery occlusion ( MCAO ) was induced in rats , and neurological deficit scores and brain infarct volumes were assessed . - pubmed
RESULTS : We showed that PTS improved neurological function and reduced infarct volumes in MCAO rats . - pubmed
CONCLUSIONS : With few alternative solutions able to address this unique and difficult problem , the structural block of vascularized bone with the extended corticoperiosteal sleeve proved able to achieve a union that had failed multiple previous attempts and able to resist reactivation of infection , in a challenging group of patients with comorbidities . - pubmed
METHODS : We conducted a retrospective case series of 68 patients with biopsy - confirmed paranasal sinus lymphoma with attention on systemic disease association . - pubmed
RESULTS : Of 63 patients with paranasal sinus lymphoma , 35 ( 56 % ) had systemic involvement . - pubmed
Four patient groups were identified : ( 1 ) primary paranasal sinus lymphoma ( 44 % ) ; ( 2 ) systemic disease occurring concurrently with paranasal sinus lymphoma ( 25 % ) ; ( 3 ) paranasal sinus lymphoma with relapse of preexisting systemic lymphoma ( 22 % ) ; and ( 4 ) progression to systemic disease after primary paranasal sinus lymphoma ( 8 % ) . - pubmed
Most of the patients with systemic disease were diagnosed at 50 + years and had positive smoking histories . - pubmed
For patients with preexisting systemic lymphoma , the mean time to paranasal sinus lymphoma was 65 months . - pubmed
Its expression was up - regulated upon white spot syndrome virus ( WSSV ) infection . - pubmed
Response to current asthma therapies also varies greatly , which is probably related to the inter - patient differences in pathogenesis . - pubmed
To approach the problem whether it is reliable to deduce hypotheses from autopsy material to explain physiological and pathological processes , we studied capillarity in pig soleus muscle 1 and 24 hr after death . - pubmed
The 2015 - 2016 Zika virus ( ZIKV ) outbreak in the Americas has brought this relatively unknown flavivirus into the spotlight as the etiologic agent of congenital Zika syndrome in newborns and , potentially , of Guillain - Barre syndrome in adults . - pubmed
ZIKV shares a high degree of amino acid sequence homology with the closely related flavivirus Dengue virus ( DENV ) . - pubmed
Due to the paucity of research investigating T cell - mediated immune responses to ZIKV , the precise roles of T cells in protection against and pathogenesis of ZIKV infection are unclear . - pubmed
In this review , we summarize our current understanding of how T cells respond to primary and secondary infections with DENV and ZIKV . - pubmed
A thorough understanding of the role of ZIKV - specific and DENV cross - reactive T cells in controlling infection is essential for developing ZIKV- and DENV - specific vaccines with maximal safety and efficacy . - pubmed
In a previous report we showed that intravenous infusion of bone marrow - derived mesenchymal stem cells ( MSCs ) improved functional recovery after contusive spinal cord injury ( SCI ) in the non - immunosuppressed rat , although the MSCs themselves were not detected at the spinal cord injury ( SCI ) site [ 1 ] . - pubmed
They could be interesting as anti - CMV and anti - tumor treatment . - pubmed
Additional trials in humans are required to assess the efficacy of artesunate and artemisinin derivatives in diseases other than malaria . - pubmed
A 34 - year - old woman presented with left flank pain and discomfort . - pubmed
In this article , we attempt to review previous studies from the medical literature concerning relapse and risk factors related to relapse in BP patients . - pubmed
Metabolic effects of light deprivation in the prefrontal cortex of rats with depression - like behavior : In vivo proton magnetic resonance spectroscopy at 7T. - pubmed
Effect of chronic pretreatment with beta - blockers on no - reflow phenomenon in diabetic patients with acute ST - elevation myocardial infarction undergoing primary percutaneous coronary intervention . - pubmed
In comparison with patients attaining TIMI 3 flow , patients with no - reflow have an increased incidence of ventricular arrhythmias , early congestive cardiac failure , cardiac rupture and cardiac death . - pubmed
Methods and results : The study included 107 diabetic patients who had presented with acute STEMI within 12 h from the onset of chest pain . - pubmed
Conclusion : Chronic pre - treatment with B - blocker in diabetic patients presenting with STEMI , is associated with lower rate of occurrence of no - reflow phenomenon after primary PCI . - pubmed
Here we investigated face processing in an adult , patient PK , diagnosed with both high functioning autism spectrum disorder ( ASD ) and developmental prosopagnosia ( DP ) . - pubmed
CONCLUSIONS : The centralization of dispatch centers was associated with an improved bystander CPR rate and dispatcher - provided CPR instructions for OHCA patients . - pubmed
The functioning of middle ear bones in such individuals were assessed in this study and it was found that the middle ear bones are equally susceptible to micro - fractures and can cause reduction in the transmission of sound energy . - pubmed
METHODS : The study included 25 normal , 39 osteopenic and 40 osteoporotic participants . - pubmed
PURPOSE : To develop a new classification system for vitreomacular traction ( VMT ) syndrome according to spectral - domain optical coherence tomography ( SD - OCT ) imaging and to investigate the clinical course of VMT patients . - pubmed
METHODS : This study included 68 eyes of 68 consecutive patients who were followed with observation or treated with vitrectomy for idiopathic VMT . - pubmed
In the 44 eyes that were managed with vitrectomy , a significantly larger percentage of patients in group C ( 4/16 [ 25 % ] ) experienced subsequent full - thickness macular hole development following vitrectomy compared with those in groups B ( 0 % ) or C ( 0 % ) ( P = 0.014 ) . - pubmed
METHODS : We retrospectively analyzed 860 patients with cT1 - 4N0M0 prostate cancer who underwent RARP ( n = 500 ) or VMAT ( n = 360 ) between 2011 and 2016 . - pubmed
VMAT patients had significantly better bRFS than RARP patients , though their definitions of biochemical recurrence differed . - pubmed
Recent successes in cancer immunotherapy have been tempered by sub - optimal clinical responses in the majority of patients . - pubmed
CONCLUSIONS : The MRI - stratified pathway detected more csPCa than the systematic TRUS - guided biopsy pathway in men with a clinical suspicion of PCa , for both biopsy - naive patients and those with prior negative biopsy . - pubmed
Pressurized intraperitoneal aerosol chemotherapy with low - dose cisplatin and doxorubicin ( PIPAC C / D ) in patients with gastric cancer and peritoneal metastasis : a phase II study . - pubmed
Patients with bowel obstruction or extraperitoneal metastasis were ineligible . - pubmed
Conclusions : PIPAC C / D was well tolerated and active in patients with RGCPM . - pubmed
However , the risk of anaphylactic reactions , long treatment duration , varying extract quality , and underrepresentation of certain allergens currently prevent many patients from successfully undergoing SIT . - pubmed
In patients who underwent MSA , the median reimbursement related to the upper gastrointestinal disease was $ 305 PMPM , at 12 months prior to surgery and $ 104 at 12 months after surgery , representing 66 % decrease in cost . - pubmed
Cholangiofibrosis and Related Cholangiocellular Neoplasms in Rodents . - pubmed
METHODS : Sixty patients with T - ALL and 60 patients with acute myelogenous leukemia ( AML ) diagnosed in our hospital from June 2012 to March 2015 were enrolled in T - ALL group and AML group , respectively . - pubmed
Purpose : Circular RNA ( circRNA ) is a key regulatory factor in the development and progression of human tumors . - pubmed
However , the working mechanism and clinical significance of most circRNAs remain unknown in human cancers , including multiple myeloma ( MM ) . - pubmed
Patients and Methods : This study employs high - throughput circRNA microarray with bioinformatics to identify differentially expressed circRNAs in patients with MM . - pubmed
The hsa_circ_0007841 expressions were observed in the MM tissues of 86 patients . - pubmed
In addition , the relationship between hsa_circ_0007841 expressions in the MM tissues and the pathological features of patients with MM were evaluated and role of hsa_circ_0007841 as a potential biomarker and therapeutic target was assessed . - pubmed
Misoprostol ameliorates doxorubicin induced cardiac damage by decreasing oxidative stress and apoptosis in rats . - pubmed
We investigated the potential cardioprotective effects of misoprostol ( MP ) on doxorubicin ( DOX ) induced cardiac damage using histologic and biochemical assessment of rat heart . - pubmed
Comparison of diagnostic sleep studies in hospitalized neurorehabilitation patients with moderate to severe traumatic brain injury . - pubmed
RESEARCH QUESTION : This study aimed to evaluate the non - inferiority and diagnostic accuracy of a portable Level 3 sleep study relative to Level 1 polysomnography in hospitalized neurorehabilitation patients with traumatic brain injury . - pubmed
The ultrastructural characteristics of bile canaliculus in porcine liver donated after cardiac death and machine perfusion preservation . - pubmed
We analyzed the intracellular three - dimensional ultrastructure of the bile canaliculi and hepatocyte endomembrane systems in porcine liver grafts after warm ischemia followed by successive MP with modified University of Wisconsin gluconate solution . - pubmed
Focal EEG changes indicating critical illness associated cerebral microbleeds in a Covid-19 patient . - pubmed
Objectives : We describe a patient suffering from Covid19 - related acute respiratory distress syndrome ( ARDS ) , highlighting the diagnostic role of the EEG in ICU . - pubmed
History : A Covid-19 patient undergoing mechanical ventilation due to related acute respiratory distress syndrome ( ARDS ) , presented altered mental status in the ICU . - pubmed
EEG plays a crucial role in these patients , allowing investigating the presence of focal or diffuse cerebral dysfunction . - pubmed
This is particularly helpful for Covid-19 patients in the ICU , where the neurological examination is challenging by the severity of the respiratory illness . - pubmed
OBJECTIVES : This study prospectively evaluated endomyocardial biopsies in patients with heart failure with preserved ejection fraction ( HFpEF ) to identify histopathologic phenotypes and their association with clinical characteristics . - pubmed
METHODS : Patients with HFpEF ( EF > = 50 % ) referred to the Johns Hopkins HFpEF Clinic between August 2014 and September 2018 were enrolled for right heart catheterization and endomyocardial biopsy . - pubmed
RESULTS : Of the 108 patients enrolled , median age was 66 years ( 25th to 75th percentile : 57 to 74 years ) , 61 % were women , 57 % were African American , 62 % had a previous HF hospitalization , median systolic blood pressure was 141 mm Hg ( 25th to 75th percentile : 125 to 162 mm Hg ) , body mass index ( BMI ) was 37 kg / m2 ( 25th to 75th percentile : 32 to 45 kg / m2 ) , and 97 % were on a loop diuretic . - pubmed
Living donor kidney transplantation is an effective option of renal replacement therapy in patients with light - chain amyloidosis ( AL ) . - pubmed
In the meantime , however , in addition to radon and tobacco - smoke , other airborne pollutants have been identified as risk - factors for lung - cancer . - pubmed
While the general increase in life - expectancy improves the cost - effectiveness of radon remediation programmes significantly , reducing tobacco - smoking incidence reduces that cost - effectiveness but with the overall benefit of reducing radon - related lung - cancers . - pubmed
OBJECTIVE : To determine the association between preoperative Patient - Reported Outcomes Measurement Information System ( PROMIS ) Physical Function ( PF ) scores with postoperative pain , narcotics use , and patient - reported outcomes ( PRO ) following a single - level anterior cervical discectomy and fusion ( ACDF ) procedure . - pubmed
Patients with greater disability reported higher VAS pain scores ( P = 0.003 ) . - pubmed
However , patients demonstrated similar improvement of VAS neck and arm pain , as well as NDI at all postoperative timepoints . - pubmed
CONCLUSION : Patients with worse preoperative disability as measured by PROMIS PF reported increased pain but comparable narcotics consumption in the immediate postoperative period following a single - level ACDF procedure . - pubmed
Page kidney was described by Page , following very elaborate experiments with animal kidneys in 1939 , with persistent arterial hypertension from " cellophane perinephritis . " - pubmed
Patient was on Apixaban , a non - vitamin K antagonist oral anticoagulant ( NOAC ) for atrial fibrillation which was withheld 3 days before the procedure . - pubmed
METHODS : This study is a retrospective review of all patients who underwent resection of a WHO grade I intracranial meningioma at the authors ' institution from 2007 to 2017 . - pubmed
Tumor recurrence occurred in 63 patients ( 12.8 % ) at a median ( IQR ) of 36 ( 40.3 ) months from surgery . - pubmed
Klebsiella pneumoniae has emerged as one of the most important pathogens that frequently encounter in community - acquired or hospital - acquired infections . - pubmed
Timely epidemiological surveillance could greatly facilitate infection control of K. - pubmed
INTRODUCTION : The use of immune - checkpoint inhibitors has drastically improved the management of patients with non - small cell lung cancer ( NSCLC ) , but innate and acquired resistances are hurdles needed to be solved . - pubmed
Syngeneic NSCLC mouse models 393P and UNSCC680AJ were used for in vivo drug testing . - pubmed
Normal non - irradiated McCoy cell cultures provide a sensitive and reproducible method for the isolation of oculo - genital strains of chlamydia A directly from human secretions and for laboratory studies with these agents . - pubmed
In 100 healthy persons and 38 patients with idiopathic thrombocytopenic purpura ( ITP ) the morphology of thrombocytes was examined according to BREDDIN . - pubmed
In the 36 months since its inception , the National Prostatic Cancer Project treatment subgroup has randomly assigned over 360 patients with progressive advanced prostatic cancer who were no longer responsive to endocrine manipulation to either one of four different clinical studies . - pubmed
New trials will introduce single- and multiple - drug chemotherapy at earlier phases of the clinical course of prostatic cancer patients . - pubmed
Vaccinia virus infection of the central nervous system in X - irradiated mice . - pubmed
The effect of X - irradiation on experimental vaccinia infection of BALB / c mice was studied . - pubmed
As compared with nonirradiated controls , the X - irradiated animals exhibited ( i ) a time lag in virus replication ( delayed , but protracted replication ) ; ( ii ) a delayed and repressed immune response : ( iii ) more severe acute cytocidal infection of leptomeninges , choroid plexus , ependyma , and vessels , with extensive damage to the brain - barrier system ; and ( iv ) noncytocidal , latent infection of glial cells and neurons . - pubmed
Hepatitis C virus ( HCV ) recently was shown to be a possible pathogenetic agent for HCC in a number of countries . - pubmed
Fifteen patients with positive findings for anti - HCV had concurrent HBV infection , 11 had serologic evidence of previous HBV infection , and only 5 patients had anti - HCV marker alone . - pubmed
The mean age of MPNT patients was greater than that of Ewing ' s sarcoma patients . - pubmed
Most importantly , however , was a statistically significant difference in prognosis : disease - free survival in Ewing ' s sarcoma patients at 7.5 years follow - up was 60 % compared with 45 % MPNT patients ( P = 0.026 ) . - pubmed
[ Malaria in intravenous drug users associated with HIV seropositivity ] . - pubmed
One case of induced malaria by Plasmodium vivax was registered in Presidente Prudente , located in the west of the State , in 1988 and a further eleven cases in 1989 . - pubmed
Pre- and postoperative mammograms were reviewed in 103 women undergoing conservation surgery and irradiation for breast cancer stage I. - pubmed
Following surgery , 71 of the patients displayed noticeable scar tissue in the surgical area , sometimes causing diagnostic difficulties . - pubmed
Two of the patients had a local recurrence of carcinoma , while 3 developed cancer in the other breast . - pubmed
By 90 min the majority of patients ( 55 % ) exhibited TIMI grade 3 flow ; infarct artery patency at 120 min was 84.9 % . - pubmed
During hospitalization definite recurrent ischemia occurred in nine patients ( 15 % ) ; nonfatal recurrent infarction was noted in one ( 1.7 % ) . - pubmed
Four patients ( 6.7 % ) experienced major bleeding , including one with intracranial bleeding . - pubmed
Mortality was significantly influenced by the occurrence of cardiogenic shock , which was present in five patients at the time of enrollment . - pubmed
Forty - seven adolescents with periodontal abnormalities were examined using clinical , immunologic , and functional tests ( altogether 12 signs ) . - pubmed
Of the 147 patients 12 developed intracerebral , epidural and subdural hematomas . - pubmed
3 persons developed infections . - pubmed
To investigate the clastogenic activity of sera from leprosy patients , normal peripheral blood lymphocytes were cultured in both inactivated and noninactivated lepromatous leprosy ( LL ) sera . - pubmed
An increase in the frequency of chromosome aberrations was observed in normal lymphocyte cultures supplemented with both inactivated ( 5.2 % ) and noninactivated ( 5.0 % ) LL serum compared to that of cultures supplemented with normal human AB+ serum ( 2.4 % ) . - pubmed
The results obtained from the inactivated LL serum showed that the factor(s ) which induce chromosomal damage , depress the mitotic index and the cell proliferation rate were not destroyed at 56 degrees C. These results are the first documentation of cytogenetic effects of LL sera on normal human peripheral blood lymphocytes . - pubmed
Effects of hypoxia and fatty acids on the distribution of metabolites in rat heart . - pubmed
Detection of Leishmania donovani soluble antigen and antibody in the urine of visceral leishmaniasis patients . - pubmed
Urine samples from 21 patients with visceral leishmaniasis were examined for the presence of Leishmania donovani soluble antigen and antibody by double counter - current immunoelectrophoresis . - pubmed
Growth failure in children with renal tubular acidosis . - pubmed
[ Superiority of a new etiopathogenic treatment curing periarteritis nodosa caused by hepatitis B virus , using a combination of brief corticotherapy , vidarabine and plasma exchange ] . - pubmed
A new physiopathological treatment of HBV - related polyarteritis inspired by advances in the treatment of chronic active hepatitis B was tested in 7 patients . - pubmed
In contrast , no patient had been cured in a similar group of 7 polyarteritis patients previously treated with the conventional symptomatic therapy using corticosteroids ( 6/7 ) , plasma exchanges ( 4/7 ) and immunosuppressants ( 2/7 ) . - pubmed
An open placebo - controlled study on eleven healthy male volunteers was carried out to investigate renal tolerance and the possibility of crystalluria after oral and intravenous administration of ofloxacin . - pubmed
[ Protective role of effectors and T - suppressors of delayed hypersensitivity in mice with a localized staphylococcal infection ] . - pubmed
To induce delayed hypersensitivity ( DH ) in mice , experimental local infection with a small dose of Staphylococcus aureus was used . - pubmed
The study revealed that the role played by DH in antistaphylococcal immunity was different in the animals infected by the subcutaneous routes ; besides , the regulatory action of T - suppressors of DH was established . - pubmed
Medroxyprogesterone acetate enhances spontaneous mammary tumorigenesis and uterine adenomyosis in mice . - pubmed
Based on our previous findings that medroxyprogesterone acetate ( MPA ) significantly suppressed the formation of preneoplastic mammary hyperplastic alveolar nodules in mice , and that this suppression persisted for some time , we studied the effects of different schedules of MPA treatment on spontaneous mammary tumorigenesis and uterine adenomyosis in SHN virgin mice . - pubmed
These results are in good accord with our previous observations with progesterone , indicating that MPA has progesterone - like effects on mammary and uterine lesions of mice . - pubmed
The records of 14 patients with a tumour in the pineal or supra - sellar region seen at The Norwegian Radium Hospital , Oslo between 1973 - 1980 have been studied retrospectively . - pubmed
The work presents the results of the study of the immune status in 18 patients with chronic bronchitis at the stage of remission , subjected to prolonged prophylactic treatment with the inhalations of levamisole solution , and in 16 patients receiving the inhalations of staphylococcal vaccine . - pubmed
The determination of the sensitivity of lymphocytes and neutrophils to incubation with levamisole by means of the rosette - formation test makes it possible to prognosticate , taking into account the initial level of spontaneous E - rosette formation of these cells , the effectiveness of the prophylactic treatment of patients with chronic bronchitis . - pubmed
Varicella - zoster infection in patients with neoplastic diseases . - pubmed
A neuron - survival assay with dissociated ciliary ganglion neurons was used to examine the level of neurotrophic activity in organs of the rat and chicken . - pubmed
In patients with suspected seizure disorders , electrical and clinical data should be correlated before interpretation is made of focal lesions seen by neuroimaging techniques . - pubmed
Urinary incontinence developed postoperatively in 2 of 8 patients operated on solely because of symptomatic genital prolapse . - pubmed
Serum anticonvulsant levels during chronic administration in the immature epileptic baboon , Papio papio . - pubmed
The compositions of the major lipids and their constituent fatty acids and fatty aldehydes from cerebral gray matter , white matter , and myelin , spinal cord myelin , and sciatic nerve were determined in a 57 yr old woman who died of Refsum ' s disease . - pubmed
Bronchial asthma observed in 2 of 16 workers ( 12.5 % ) was reactive in a skin drop test with 1 % chloroplatinate , and typical bronchial asthma was induced in an environmental provocation test carried out in a room where platinum sensors are made . - pubmed
The main symptoms revealed by physical examination of workers exposed to chloroplatinate contact dermatitis in 11 ( 78.6 % ) , pharyngeal irritation in 6 ( 42.9 % ) , nasal obstruction in 2 ( 14.3 % ) , frequent sneezing , coughing , and sputum in one each. - pubmed
Between October 1969 and December 1979 , a total of 440 patients who had diffuse coronary artery disease were treated with combined endarterectomy and coronary bypass grafting . - pubmed
Endarterectomy is a valuable additional procedure in the management of patients with diffuse coronary artery disease . - pubmed
To investigate further the modulation of autoimmune disease by nutritional means , the influence of zinc deprivation upon the development of the immunopathology of MRL / I mice was studied . - pubmed
Because some effects of zinc deficiency may be due to associated inanition and consequent caloric deprivation , mice with similarly restricted food intake but adequate zinc intake were also studied . - pubmed
When zinc deficiency was introduced at 4 wk of age , a significant delay in the appearance of the physical findings of MRL / I mice , including open sores , necrotic ears , arthritis , and end - stage cachexia , was noted . - pubmed
In addition , zinc deficiency introduced at this age resulted in a lower incidence and titer of antibodies to dsDNA and less severe glomerulonephritis than control mice . - pubmed
Pair - fed controls also showed delayed progression of their disease , but animals restricted isocalorically from 4 wk of age experienced a more rapid onset of the lupus - like syndrome than did their zinc - deprived counterparts . - pubmed
We evaluated 64 children with 72 ureteroceles who underwent operation . - pubmed
Levels were significantly higher in patients with giant cell arteritis ( mean 2.04 ng / ml ) , polyarteritis nodosa ( mean 2.08 ng / ml ) , scleroderma ( mean 2.27 ng / ml ) , and SLE ( mean 3.93 ng / ml ) . - pubmed
CONCLUSION : Our findings may reflect a low degree of endothelial cell activation in healthy persons that is increased in inflammatory diseases involving blood vessels . - pubmed
The growth and rupture of 40 cerebral aneurysms was studied in 36 patients ( 14 men , 22 women ; were average age , 51.8 years ) . - pubmed
The adenoma patients all suffered hypertension , whereas one of the adenoma patients and the carcinoma patient showed signs of DM . - pubmed
Thus , the present analysis of the six incidentaloma patients suggests that once an adrenal incidentaloma patient with hypertension and/or DM is found , both endocrinological and imaging examinations are necessary to determine the indication of surgical treatment . - pubmed
In patients with hepatitis and liver cirrhosis , the decrease did not , however , affect the gamma - Gla excretion . - pubmed
In addition , in patients with hepatoma or carcinoma with liver metastases , the urinary gamma - Gla levels were increased . - pubmed
However , in a series of seven consecutive patients with severe visual deficit due to ethambutol toxicity , only 42.2 % ( 3 of the 7 patients ) achieved a visual recovery of better than 20/200 after an average follow - up of 8.3 + /- 2.1 months after stoppage of the drug . - pubmed
As an additional sidelight , the value of visually evoked potential in the monitoring of patients on ethambutol , especially in cases with early periaxial neuritis , has been emphasised . - pubmed
Gas in the tissues -- a complication of pelvic surgery in the subclinical diabetic patient . - pubmed
The histopathology of the portal vein in human extrahepatic portal vein obstruction ( EHPVO ) in the form of cavernomatous transformation of the portal vein is well documented . - pubmed
An experimental model of EHPVO was created by partial ligation of the portal vein in 20 rats . - pubmed
Development of portal hypertension was confirmed by measurement of intrasplenic pulp pressure ( 19.7 + 7.1 cm normal saline vs 12.9 + 1.1 cm of normal saline in SO rats ) . - pubmed
While SO animals showed mild focal sinusoidal congestion and a normal portal vein , the experimental group of animals with EHPVO showed oedema around the portal vein , multiple dilated vascular channels near the hilum resembling cavernomatous transformation and severe sinusoidal congestion . - pubmed
Thus experimental EHPVO does reproduce some histological changes observed in human EHPVO . - pubmed
Laser - Doppler flowmetry measurements of subcortical blood flow changes after fluid percussion brain injury in rats . - pubmed
Laser - Doppler flowmetry ( LDF ) was used to record subcortical cerebral blood flow in hippocampus and striatum immediately following parasaggital fluid percussion brain injuries of mild to moderate severity ( 2.58 + /- 0.09 atm , 10 - 11 msec duration ) in spontaneously breathing anesthetized rats . - pubmed
Subsequent beam - walk , beam - balance , and rope - hang assessments revealed significant neurological impairments in the injured rats but not in the sham controls . - pubmed
Forty pediatric patients , ranging from 5 - 13 years of age and suffering from grass pollen rhinoconjunctivitis , were submitted to local nasal preseasonal ( 12 weeks ) immunotherapy , either with a grass pollen extract or with placebo . - pubmed
After only 1 year , the actively treated patients showed a significant decrease of daily nasal and conjunctival signs and symptoms - as judged by a 1 to 3 score - in comparison with the control group . - pubmed
Impaired monocyte function in patients successfully treated for Whipple ' s disease . - pubmed
Peripheral blood mononuclear cells ( monocytes ) from patients with Whipple ' s disease in long - term remission were tested for their ability to handle intracellular microorganisms . - pubmed
[ Changes in brain monoamine neurotransmitter in iron deficiency nonanemic rats ] . - pubmed
An iron deficiency nonanemic rat model was established by feeding with low - iron diet ( 11.9 mg / kg ) to study if there exists biochemical abnormality in brain tissues . - pubmed
It indicated that there existed metabolic abnormality of monoamine neurotransmitter in the brain tissues of iron deficiency nonanemic rats . - pubmed
To calculate canal compromise and decrease of midsagittal diameter caused by retropulsion of fragments into the spinal canal we analyzed the pre- and postoperative computed tomographies of 32 patients with unstable thoracolumbar burst fractures treated by USS ( universal spine system ) . - pubmed
10 of 13 patients presented a postoperative improvement of neurological deficit , no neurological deterioration occurred . - pubmed
[ Disorders of the blood microcirculation in patients with suppurative - necrotic complications in diabetes mellitus and the approaches to their correction ] . - pubmed
The results of surgical treatment of 153 patients with diabetes mellitus , suffering from purulent - necrotic complications , were analyzed . - pubmed
Ruby laser treatment for hirsutism : clinical response and patient tolerance . - pubmed
The first treatment was followed by mild , short - lived erythema and swelling in 60 % ( 25 of 42 ) patients . - pubmed
gamma delta T cells accumulate during Plasmodium infections in both murine and human malarias . - pubmed
We examined the accumulation of gamma delta T cells elicited during infection with virulent and avirulent Plasmodium yoelii parasites in relatively susceptible and resistant strains of mice . - pubmed
Effects of percutaneous balloon mitral valvuloplasty and exercise training on the kinetics of recovery oxygen consumption after exercise in patients with mitral stenosis . - pubmed
METHODS AND RESULTS : Thirty patients with mitral stenosis ( valve area & lt ; or = 1.0 cm2 ) and same sized age- and size - matched healthy volunteers were included for this study . - pubmed
Thirty consecutive patients who underwent successful percutaneous balloon mitral valvuloplasty ( valve area & gt ; or = 1.5 cm2 and mitral regurgitation grade & lt ; or = 2 ) , were randomized to an exercise training group or non - training group . - pubmed
Spiral nitinol biliary stents in a porcine model : evaluation of the potential for use in benign strictures . - pubmed
Presynaptic inhibition in humans : a comparison between normal and spastic patients . - pubmed
During the last 40 years , several studies in man have been devoted to the pathophysiological mechanisms underlying spasticity . - pubmed
Delwaide showed that the vibration - induced inhibition of Ia fibres is reduced in spastic patients . - pubmed
This paper is thus devoted to a review of the methods recently developed to study selectively presynaptic Ia inhibition in man and to a reevaluation of the relations between modifications in presynaptic Ia inhibition and spasticity in hemiplegic and spinal spastic patients . - pubmed
HIV-1 infection can lead to severe central nervous system ( CNS ) clinical syndromes in more than 50 % of HIV-1 positive individuals . - pubmed
PATIENTS : Eight patients ( mean age , 55.1 + /- 12.1 yr ; mean duration to block , 4.4 + /- 3.7 mo ) with chronic hemiplegia and severe spasticity ( modified Ashworth scale [ MAS ] score & lt ; 2 ) secondary to cerebrovascular accidents ( n = 5 ) and traumatic brain injuries ( n = 3 ) . - pubmed
The influence of hemocoagulative disorders on the outcome of children with head injury . - pubmed
BACKGROUND : Although disseminated intravascular coagulation ( DIC ) and other hemocoagulative abnormalities are severe complications of head injury , their effect on clinical outcome remains unclear , particularly among children . - pubmed
OBJECTIVES : To evaluate the frequency of hemocoagulative abnormalities and their influence on outcome among children with head injury . - pubmed
RESULTS : Among children with severe head injury , 22.2 % ( 6/27 ) developed DIC , all of whom died and had shown severe brain edema . - pubmed
The third case occurred in an infant who died at birth and demonstrated a well - circumscribed tumor that did not invade adjacent brain parenchyma . - pubmed
BACKGROUND : Optical coherence tomography was used for the examination of patients with geographic atrophy in different stages of age - related macular degeneration . - pubmed
PATIENTS AND METHODS : 37 patients with geographic atrophy ( n = 55 eyes ) out of 150 with AMD ( n = 169 eyes ) were examined . - pubmed
Risk of cataract in patients treated with statins . - pubmed
Clinical safety data of statins regarding cataract development in humans have been of limited value so far . - pubmed
The main outcome was a first - time diagnosis of cataract and/or cataract extraction in patients aged 40 to 79 years . - pubmed
PATIENTS AND METHODS : From August 1994 to February 2000 , 285 consecutive patients underwent endoscopic lithotripsy with either the Swiss Lithoclast pneumatic lithotripter ( 145 patients ) or the Ho : YAG laser lithotripter ( 140 patients ) for the treatment of ureteral calculi . - pubmed
Methicillin - resistant Staphylococcus aureus ( MRSA ) nosocomial infections ( according to the definitions of nosocomial infections ) of the Centers for Disease Control and Prevention in the surgical ward were retrospectively studied in two periods : from February 1989 to June 1990 and from January 1992 to December 1994 . - pubmed
METHODS : Between January 1993 and December 1999 , a total of 62 consecutive patients with mitral valvular disease , whose preoperative left atrial endodiastolic volume index & gt;/= 300 ml / m(2 ) or endosystolic diameter & gt;/= 6.0 cm , were enrolled as research candidates . - pubmed
CONCLUSION : The morphologic classification of GLA may represent the main pathophysiological changes of GLA and might be a guideline for the selection of the optimal plication procedures of GLA in patients with valve diseases . - pubmed
The ocular pharmacokinetics of a single topical administration of a fixed combination ( FC ) of latanoprost 0.005 % and timolol 0.5 % was compared to the monotherapies of latanoprost and timolol in cataract surgery patients . - pubmed
Suppression of the contact hypersensitivity response following topical exposure to 2 - butoxyethanol in female BALB / c mice . - pubmed
The effects of route of exposure , time of exposure and metabolism of 2 - butoxyethanol ( BE ) on the contact hypersensitivity response ( CHR ) were evaluated in female BALB / c mice . - pubmed
Blocking the metabolism of BE by oral administration of 4 - methylpyrazole ( MP ) , further reduced OXA - induced ear swelling when compared to mice exposed to BE without MP treatment . - pubmed
METHODS : The cytopathology database at the New York University Medical Center was searched for women who underwent surgical excision after a breast FNAB diagnosis of a papillary lesion . - pubmed
[ Development of experimental tuberculosis in guinea pigs treated with thymol silver sulfone ] . - pubmed
Because inosine is able to enhance T - cell proliferation and reverse immunosuppression in vitro , both mechanisms may have aggravated the disease course in our patient , once the autoimmune process of dermatomyositis has been initiated . - pubmed
In this patient , cystic lesions persisted after successful treatment of Mycobacterium tuberculosis and resulted in spontaneous pneumothorax with persistent air leak . - pubmed
METHODS : PBMC from 30 patients allergic to pollen undergoing SIT were collected during the therapy . - pubmed
Control PBMC were collected from 10 patients with allergic rhinitis not participating in SIT and from 10 nonallergic subjects . - pubmed
Effect of challenge dose and age in experimental infection of pigs with encephalomyocarditis virus . - pubmed
Two experiments were performed to compare the severity of encephalomyocarditis virus ( EMCV ) infection in pigs . - pubmed
The pigs were challenged with the Greek myocardial strain , at different ages and with different doses . - pubmed
In the first experiment , nineteen susceptible pigs , 40 days old , were divided into three groups and were experimentally infected with 10(6 ) TCID(50 ) , 10(4 ) TCID(50 ) or 10(2 ) TCID(50 ) of the Greek EMCV strain . - pubmed
In the second experiment , 10 susceptible pigs , of either 20 or 105 days , were divided into two groups according to age and were experimentally infected with 10(6 ) TCID(50 ) of the Greek EMCV strain . - pubmed
The severity of the macroscopical and the histopathological heart lesions was inversely related to the age of the pigs . - pubmed
Viraemia , and nasal and faecal excretions were detected in all groups and lasted 1 - 3 days , except for the 105 - day - old pigs whose symptoms lasted for an additional day . - pubmed
Critics ignore or reject important evidence including , for example , large numbers of unexplained HIV infections in children , strong associations between incident HIV and injections , and genetically - linked infections in persons with no known sexual contact . - pubmed
In any case , because each iatrogenic infection causes subsequent linked infections , the impact of HIV transmission through health care has been underestimated . - pubmed
CONCLUSION : Baseline HRQL is a statistically significant predictor of survival for patients with advanced lung cancer . - pubmed
The following were identified and analysed : type of injury ( low or high - energy transfer ) , treatment ( early / late ) , complications , patient demographics and compliance . - pubmed
Osteoporosis case finding in the general practice : phalangeal radiographic absorptiometry with and without risk factors for osteoporosis to select postmenopausal women eligible for lumbar spine and hip densitometry . - pubmed
Different hemodynamic stress of the ascending aorta wall in patients with bicuspid and tricuspid aortic valve . - pubmed
We performed an echocardiographic study to examine the differences in hemodynamic stress at the ascending aorta in patients with bicuspid and tricuspid aortic valve . - pubmed
We studied prospectively 58 consecutive patients referred for preoperative echocardiographic examination with aortic valve stenosis and either bicuspid or tricuspid valve and an ascending aortic diameter of & lt;/=4.5 cm . - pubmed
The second case was a 68 - year - old woman followed for hepatitis C associated with a mixed cryoglobulinemia ( type II ) , who had sensory disturbances in the lower limbs . - pubmed
Cerebrospinal fluid studies showed a normal protein content without pleocytosis in both patients . - pubmed
CONCLUSIONS : This preliminary IVUS study suggests that ARB could cause regression of coronary atherosclerosis in humans . - pubmed
BACKGROUND : Histological transformation ( HT ) is a well - known event in patients with follicular lymphoma ( FL ) conferring an unfavorable prognosis . - pubmed
The aim of the study was to analyze incidence and risk factors for HT in a large series of FL patients . - pubmed
PATIENTS AND METHODS : 276 patients ( median age : 54 years ; M139 / F137 ) diagnosed with FL ( 42 % grade 1 , 51 % 2 , 7 % 3 ) in a single institution were studied . - pubmed
RESULTS : 30 of 276 patients ( 11 % ) presented HT after a median follow - up of 6.5 years , with a risk of 15 % and 22 % at 10 and at 15 years , respectively . - pubmed
Only FLIPI predicted HT in grade 1 - 2 patients . - pubmed
No significant differences were found in incidences of ventilator - associated pneumonia ( eight studies , 1,272 patients ) and mortality ( four studies , 1,062 patients ) . - pubmed
METHODS : One hundred and one patients with MM and 101 healthy donors matched for age and sex were enrolled . - pubmed
The role of tobacco smoke induced mitochondrial damage in vascular dysfunction and atherosclerosis . - pubmed
The majority of individuals chronically exposed to tobacco smoke will eventually succumb to cardiovascular disease ( CVD ) . - pubmed
However , despite the major cardiovascular health implications of tobacco smoke exposure , concepts of how such exposure specifically results in cardiovascular cell dysfunction that leads to CVD development are still being explored . - pubmed
Moreover , surprisingly little is known about the effects of prenatal and childhood tobacco smoke exposure on adult CVD development . - pubmed
By virtue of its multiple , essential roles in cell function including energy production , oxidant signaling , apoptosis , immune response , and thermogenesis , damage to the mitochondrion will likely play an important role in the development of multiple common forms of human disease , including CVD . - pubmed
Specifically , this review will discuss the potential role of tobacco smoke and environmental oxidant exposure in the induction of mitochondrial damage which is related to CVD development . - pubmed
Aspects of both adult and developmental ( fetal and childhood ) exposure to tobacco smoke on mitochondrial damage , function and disease development are also discussed , including the future implications and direction of studies involving the role of the mitochondrion in influencing disease susceptibility mediated by environmental factors . - pubmed
The current study aimed to determine these excretions in patients with Parkinson ' s disease ( PD ) receiving L - dopa compared with suitable controls . - pubmed
METHODS : Using one - way analysis of variance ( ANOVA ) , urine catecholamines and metabolites , expressed as mmol per mole creatinine , were compared in : patients with PD who were receiving L - dopa ; patients with PD but not receiving L - dopa ; and patients without PD who were being investigated for the presence of phaechromocytoma but were found not to have the disease . - pubmed
RESULTS : Significantly higher values for urinary dopamine , homovanillic acid , free normetadrenaline and free metadrenaline were found in patients with PD receiving L - dopa compared with the other two control groups . - pubmed
In all the patients with PD , these four analytes were significantly correlated with daily dose of L - dopa . - pubmed
METHODS : Patients with treatment - resistant morbid obesity were invited to participate in a randomized , double - blind , sham - controlled trial of 4 - month duration . - pubmed
Comparison of postoperative complications of 60- and 70 - year - old patients after lung surgery . - pubmed
Clinical studies have demonstrated that islet transplantation may be a useful procedure to replace beta cell function in patients with Type 1 diabetes . - pubmed
Symptomatic candidiasis : Using self sampled vaginal smears to establish the presence of Candida , lactobacilli , and Gardnerella vaginalis . - pubmed
Efficacy of nitazoxanide against experimental cryptosporidiosis in goat neonates . - pubmed
METHODS : Eighty patients with difficult endoscopic sphincterotomy because of periampullary diverticulum or prior sphincterotomy underwent balloon dilatation ( n=46 ) or sphincterotomy ( n=34 ) for lithotripsy . - pubmed
BACKGROUND : Management of patients with an abdominal aortic aneurysm ( AAA ) and malignancy is challenging . - pubmed
METHODS : The outcomes for patients diagnosed with AAA and lung cancer between 1991 and 2004 at our institution were reviewed retrospectively . - pubmed
RESULTS : We identified 75 patients with both lesions among 1,096 AAA and 1,875 lung cancer patients . - pubmed
Treatment for AAAs greater than 5.5 cm should be based on stage , histology , and patient comorbidities . - pubmed
Strong cytoplasmic incompatibility and high vertical transmission rate can explain the high frequencies of Wolbachia infection in Japanese populations of Colias erate poliographus ( Lepidoptera : Pieridae ) . - pubmed
We found that the Wolbachia infection frequencies of the butterfly Colias erate poliographus were high ( 85.7 - 100 % ) in seven Japanese populations . - pubmed
As part of studies of metabolites from fungi common in the built environment in Canadian homes , we investigated metabolites from strains of three Eurotium species , namely E. - pubmed
METHODS : This was done by assessing changes in caries prevalence in the mouth of children aged 12 to 14 year- old . - pubmed
Dobutamine enhances alveolar fluid clearance in a rat model of acute lung injury . - pubmed
Acute lung injury ( ALI ) and its most severe form , acute respiratory distress syndrome ( ARDS ) , remain leading factors for morbidity and mortality in critically ill patients . - pubmed
The present study was designed to determine whether the administration of dobutamine decreases pulmonary edema and stimulates AFC in a rat model of lipopolysaccharide - induced lung injury . - pubmed
However the understanding of pulmonary vascular remodeling in patients with CTEPH is incomplete . - pubmed
Pulmonary endarterectomy of the obstructing thromboembolic material should be performed in patients who are accessible to surgery . - pubmed
In patients who are judged inoperable or with persistent pulmonary hypertension treatment with pulmonary arterial hypertension medications can be considered . - pubmed
Tuberculosis caused by Mycobacterium microti in South American camelids . - pubmed
BACKGROUND : Infection with Mycobacterium microti can cause chronic disease in animals and threaten human health through its zoonotic potential . - pubmed
METHODS : Description of 10 llamas and 1 alpaca , aged 4 - 18 years , from 6 herds with a history of wasting and weakness admitted to the Vetsuisse - Faculty of Berne over 8 years . - pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : Infection caused by M. - pubmed
microti infection have been reported in immunocompromized human patients , the zoonotic potential of the organism should be kept in mind when dealing with this disease in SAC . - pubmed
The evaluation of vestibular functions in patients with pseudoexfoliation syndrome . - pubmed
The main objective of the study is to evaluate vestibular system of the inner ear with postural tests in the patients with pseudoexfoliation syndrome ( PEX ) . - pubmed
The study group included 34 patients with PEX and 40 controls without PEX . - pubmed
Although none of the 34 patients with PEX had clinical history of balance disturbance , 21 ( 61.76 % ) had significant pathologic sign in vestibular function tests ( P & lt ; or = 0.05 ) , while only 3 ( 7.5 % ) of 40 cases in the control group had pathologic sign in vestibular function tests . - pubmed
In conclusion , the patients with PEX , there may be a vestibular involvement in the pathological level in the inner ear . - pubmed
Larger clinical studies , experimental animal studies , and post mortem studies in humans are needed to disclose the pathology in the vestibulocochlear system in the patients with PEX . - pubmed
Human U-87 MG and U-118 MG glioma cells and rat C6 glioma cells were chosen for the study . - pubmed
The scaffolds pre - cultured with U-87 MG and C6 cells were then implanted into nude mice to evaluate tumor growth and blood vessel recruitment compared to the standard 2D cell culture and 3D Matrigel matrix xenograft controls . - pubmed
Coffee and tea consumption and endometrial cancer risk in a population - based study in New Jersey . - pubmed
We evaluated the role of tea and coffee and substances added ( sugar / honey , creamers , and milk ) on endometrial cancer risk in a population - based case - control study in six counties in New Jersey , including 417 cases and 395 controls . - pubmed
Our results indicate that sugars and milk / cream added to coffee and tea should be considered in future studies evaluating coffee and tea and endometrial cancer risk . - pubmed
Here , by using human specimens and three mouse models of ovarian cancer , we tested the feasibility of nonlinear imaging approaches , the multiphoton microscopy ( MPM ) and second harmonic generation ( SHG ) to serve as complementary tools for ovarian cancer diagnosis . - pubmed
SUMMARY OF BACKGROUND DATA : IVC filters are increasingly being used as prophylaxis against postoperative pulmonary embolism in patients undergoing bariatric surgery , despite a lack of evidence of effectiveness . - pubmed
BACKGROUND : The prognosis for patients with extensive - stage small - cell lung cancer remains poor . - pubmed
Six patients did not begin treatment with imatinib because of disease progression , persistent toxicity , or referral for radiation therapy . - pubmed
The irinotecan / cisplatin regimen was well tolerated ( grade 1/2 neutropenia , 29 % ; anemia , 43 % ; thrombocytopenia , 14 % ; and diarrhea , 29 % ) , except in 1 patient with grade 3 vomiting . - pubmed
Imatinib toxicity included grade 1/2 nausea in 50 % of the patients , peripheral edema in 75 % of the patients , grade 3 fatigue in 13 % of the patients , and neutropenia in 13 % of the patients . - pubmed
These methods were translated to rodent , large mammal , and human kidneys , and then to rodent and human tissues with advanced CKD . - pubmed
Comparative in vitro studies demonstrated that phenotype and key functional attributes were retained consistently in ex vivo cultures regardless of species or disease state , suggesting that autologous sourcing of cells that contribute to in situ kidney regeneration after injury is feasible , even with biopsies from patients with advanced CKD . - pubmed
This fat - soluble vitamin should be measured in patients who have undergone gastric bypass surgery and deficiency should be suspected in those with evidence of protein - calorie malnutrition . - pubmed
Exclusive and adjuvant radiotherapy in breast cancer patients with synchronous metastases . - pubmed
However , several studies suggest that surgical excision of the primary tumor can prolong these patients ' survival . - pubmed
Here we discuss current issues regarding exclusive and adjuvant locoregional radiotherapy in breast cancer patients with synchronous metastases . - pubmed
SUMMARY : Several studies suggest that surgery or exclusive irradiation of the primary tumor is associated with better survival in breast cancer patients with synchronous metastases and that exclusive locoregional radiotherapy may represent an effective alternative to surgery in this setting . - pubmed
Results of well - designed prospective studies are needed to re - evaluate treatment of the primary breast tumor in patients with metastases at diagnosis , and to identify those patients who are most likely to benefit . - pubmed
A larger 9.5Mb deletion ( 34.6 - 43.9Mb ) was observed in a 20 - year - old man with a more severe clinical picture including seizures and limited speech . - pubmed
All compounds isolated were evaluated for their cytotoxicity against HL-60 , A549 , and MCF-7 human cancer cell lines . - pubmed
Appropriate hearing screening in the pediatric patient with head trauma . - pubmed
PURPOSE : To develop an algorithm for the appropriate audiologic screening of in children with head trauma . - pubmed
METHODS : Participants were the first consecutive 50 children admitted to a children 's hospital trauma service after October 1 , 2005 , whose injuries resulted in a Glasgow Coma Scale ( GCS ) score & lt;=13 and/or loss of consciousness ( LOC ) but no history of hearing loss . - pubmed
CONCLUSIONS : Any child with head trauma and clinical or radiologic evidence of temporal bone fracture should have early hearing evaluation . - pubmed
The authors report a case of a cervical periosteal chondroma in a 38 - year - old man presenting with neck pain and a syndrome of spinal cord compression . - pubmed
This article reports on new neuroimaging markers for the diagnosis of Alzheimer ' s disease and particularly recent multi - functional magnetic resonance imaging ( m - fMRI ) studies in patients with schizophrenic and affective psychoses . - pubmed
INTRODUCTION : Lenalidomide is an IMiDs oral immunomodulatory compound developed for the treatment of patients with multiple myeloma ( MM ) and myelodysplastic syndromes ( MDS ) . - pubmed
The necessity for early adverse - event management , including dose modifications for neutropenia and thrombocytopenia , and venous thromboembolism prophylaxis , where applicable , in order to maintain patients on treatment and achieve optimal efficacy , is discussed . - pubmed
Secondary primary malignancies in MM and progression to acute myeloid leukemia in MDS patients in the context of lenalidomide treatment are also discussed . - pubmed
PATIENTS AND METHODS : Retrospective study of 14 patients with 15 Bosniak type 2F and 3 renal cysts on contrast enhanced CT . - pubmed
BACKGROUND : Previous work indicates that single word intelligibility tests developed for dysarthria are sensitive to segmental production errors in aphasic individuals with and without apraxia of speech . - pubmed
Target of rapamcyin ( TOR)-based therapeutics for cardiomyopathy : insights from zebrafish genetics . - pubmed
BACKGROUND : Hypothermia is becoming a common treatment for newborns with hypoxic ischaemic encephalopathy . - pubmed
Using a 5alpha - dihydrotestosterone ( DHT)-induced rat model that recapitulates the reproductive and metabolic phenotypes of human PCOS , we have examined the steroidogenic capability of granulosa cells from DHT - treated rats . - pubmed
Acute Delta ( 9 )- tetrahydrocannabinol blocks gastric hemorrhages induced by the nonsteroidal anti - inflammatory drug diclofenac sodium in mice . - pubmed
Although inhibitors of endocannabinoid catabolic enzymes protect against gastropathy in fasted NSAID - treated mice , the gastroprotective effects of Delta ( 9 )- tetrahydrocannabinol ( THC ) , the primary psychoactive component of marijuana , have yet to be investigated . - pubmed
In separate groups of mice , the cannabimimetic behavioral effects of Delta ( 9 )- THC given via each route of administration were compared using a battery of tests , consisting of assessment of locomotor activity , nociception in the tail withdrawal test , catalepsy in the bar test , and hypothermia . - pubmed
Bone mineral loss induced by anticancer treatment for gynecological malignancies in premenopausal women . - pubmed
METHODS : This study enrolled 35 premenopausal women ( 15 ovarian cancers ( OCs ) , 9 endometrial cancers ( ECs ) , and 11 cervical cancers ( CCs ) ) who underwent surgical treatment that included bilateral oophorectomy with or without adjuvant platinum - based chemotherapy in OC and EC patients , or concurrent chemo - radiation therapy ( CCRT ) in CC patients according to the established protocols at the Osaka Medical College Hospital between 2006 and 2008 . - pubmed
Rif(r ) strains were obtained by in vitro selection of H. - pubmed
Mineral composition of urinary calculi from potbellied pigs with urolithiasis : 50 cases ( 1982 - 2012 ) . - pubmed
OBJECTIVE : To determine the mineral composition and anatomic location of urinary calculi and to investigate sex and reproductive status as predisposing factors for development of urolithiasis in potbellied pigs . - pubmed
DESIGN : Retrospective case series SAMPLES : Urinary calculi from 50 purebred and crossbred potbellied pigs . - pubmed
PROCEDURES : Laboratory records for urinary calculi of potbellied pigs submitted to the University of California - Davis Stone Laboratory from 1982 through 2012 were reviewed . - pubmed
CONCLUSIONS AND CLINICAL RELEVANCE : In contrast to results from studies in commercial pigs , the most common composition of urinary calculi identified in purebred and crossbred potbellied pigs was amorphous magnesium calcium phosphate . - pubmed
Potential predisposing factors for urolithiasis in potbellied pigs may be similar to those for urolithiasis in commercial pigs . - pubmed
OBJECTIVES / HYPOTHESIS : To assess the hearing status of trisomy 21 patients by analyzing electrophysiological and radiological findings of any correlation between hearing impairment and major or minor inner ear malformations . - pubmed
METHODS : A group of 34 ears of Down syndrome subjects and 20 ears of a volunteer age- and sex - matched control group of 10 normal subjects were studied electrophysiologically by means of otoacoustic emissions and auditory brainstem response . - pubmed
Is propranolol of benefit in pediatric burn patients ? - pubmed
PURPOSE : This study evaluates the incidence trends and clinical outcomes of children with hepatocellular carcinoma ( HCC ) and assesses factors predictive of patient survival . - pubmed
METHODS : The Surveillance , Epidemiology , and End Results registry was queried from 1973 to 2009 for all patients between ages 0 and 19 with primary HCC . - pubmed
Demographics , tumor histology , surgical intervention , and patient survival were collected . - pubmed
Fibrolamellar subtype tumors were exclusive to children & gt;5years old and exhibited greater survival compared to non - fibrolamellar subtype ( 57 % vs. 28 % , respectively , p=0.002 ) . - pubmed
Tumor extirpation for patients with resectable disease significantly improved overall survival at 5years compared to no surgery ( 60 % vs. 0 % , respectively , p<0.0001 ) . - pubmed
In this report , we describe an 11 - yr - old kidney transplant recipient boy who developed immune - mediated glomerulonephritis with light microscopic , immunofluorescence , and ultrastructural features compatible with acute PIGN superimposing chronic PVN , discuss this unusual association and the possible mechanisms of antigen clearance in PVN and present a literature review . - pubmed
OBJECTIVE : To analyze the clinical characteristics and therapeutics of elderly patients with breast carcinomas . - pubmed
RESULTS : They accounted for 14.6 % ( 312/2137 ) of breast cancer patients treated during the same period . - pubmed
Ten patients who had sustained traumatic dorsolumbar vertebral fractures with complete paraplegia were recruited for this study . - pubmed
RESULTS : The overall wound infection rate was 12 % , ( 12.2 % for males and 11.1 % for females ) . - pubmed
The overall wound disruption rate was 6 % , ( 6.1 % for males and 5.5 % for females ) and the overall recurrence rate was 7 % . - pubmed
Epileptic patients have intellectual disability and behavioral co - morbidities to the tune of up to 25 and 75 % respectively . - pubmed
Cognitive impairment seen in epileptic children include difficulties in learning , memory , problem solving as well as concept formation . - pubmed
Investigating a child with epilepsy for cognitive and behavioral impairment is difficult as these tests would require cooperation from the patient 's side to a significant extent . - pubmed
RESULTS AND DISCUSSION : The identification of factors predictive of anxiety disorders will possibly allow for effective preventive measures or early treatment interventions , respectively , and reduce the individual patient 's suffering as well as the overall socioeconomic burden of anxiety disorders . - pubmed
The drug has been used successfully to treat malaria patients in clinical studies , thus validating IspC as an antimalarial target . - pubmed
Selected prodrugs and parent compounds were also tested for their cytotoxicity toward HeLa cells and in vivo in a Plasmodium berghei malaria model as well as in the SCID mouse P. - pubmed
This uncertainty has led to inconsistencies in the medical literature and understandable confusion by clinicians about the appropriate labels for " M. - pubmed
Pulmonary valve regurgitation was reported in 17.4 % of patients , and was not related to either successful outcome or balloon size . - pubmed
Two patients ( 1.5 % ) developed restenosis that required repeat BPV . - pubmed
Prevention of atherosclerosis by Yindan Xinnaotong capsule combined with swimming in rats . - pubmed
The aim of the present study is to evaluate the joint effect of YXC and exercise on atherosclerosis in rats . - pubmed
METHODS : A combined method involving low shear stress and a high - fat diet was used to establish the atherosclerosis model in rats . - pubmed
CONCLUSIONS : In conclusion , this study indicates that the combination of YXC and swimming may prevent atherosclerosis through a synergistic effect between YXC and swimming in improving blood circulation , hemorheological parameters , blood lipids levels and the vascular endothelium in rats . - pubmed
The authors present a patient who experienced bifrontal intracranial hemorrhage and subarachnoid hemorrhage due to a ruptured iatrogenic frontopolar artery pseudoaneurysm caused during routine endoscopic sinus surgery . - pubmed
Seronegative syphilis in a patient co - infected with HIV . - pubmed
High - intensity ECC was purposefully selected to maximize the opportunity for muscle damage and hypertrophic signaling in our novel in vivo animal model . - pubmed
Shared decision - making , control preferences and psychological well - being in patients with RPE65 deficiency awaiting experimental gene therapy . - pubmed
The aim of this study was to analyze the psychological aspects of patients with RPE65 deficiency awaiting potential enrollment in gene therapy trials . - pubmed
METHODS : Five patients with genetically proven RPE65 deficiency took part in this study . - pubmed
ent-3beta - Hydroxyatis-16 - ene-2,14 - dione ( 5 ) , 7 and its aglycon , ent-19 - hydroxy - atis-16 - ene-3,14 - dione ( 7a ) , showed significant inhibitory activity on mammosphere formation in human breast cancer MCF-7 cells at a final concentration of 10 muM. - pubmed
There were 30 children ( 36 % ) with injuries of the upper cervical spine , 53 ( 63 % ) with injuries of the lower cervical spine and 1 patient ( 1 % ) with a combined injury of upper cervical spine and thoracic spine . - pubmed
In conclusion , mechanisms and patterns of injury in children are age related and the majority of the children had good outcome . - pubmed
With further advancements and experience , our knowledge in this era of precision medicine will likely lead to strides in improving the quality of life and overall survival of patients with BM from NSCLC . - pubmed
In trinitrobenzene - sulfonic acid - induced colitic rats indicated that CGA supplementation improved mitochondria ultrastructure and decreased mitochondrial injury . - pubmed
Daily intake of diets containing CGA , such as coffee and honeysuckle , may be useful for prevention of intestinal diseases . - pubmed
CONCLUSION : Socio - economic factors , educational factors and human resource factors were found have been associated with childhood caries gap between the developed and less developed nations . - pubmed
BACKGROUND : Children diagnosed with neurodevelopmental conditions such as cerebral palsy ( CP ) are at risk of experiencing restrictions in social activities negatively impacting their subsequent social functioning . - pubmed
in a cohort of children diagnosed with cerebral palsy ( CP ) . - pubmed
The double blind combination of Rituximab by IntraVenous and IntraThecAl injection versus placebo in patients with Low - Inflammatory SEcondary progressive MS ( RIVITALISE ; NCT01212094 ) trial was designed to answer : ( 1 ) Whether an induction dose of intravenous and intrathecal rituximab efficiently depletes CNS B cells ? - pubmed
For a patient with renal failure , the treatment of choice is often a simultaneous transplant of the pancreas and kidney or pancreas after kidney . - pubmed
There is some evidence of benefit with respect to the progression of secondary diabetic complications in patients with functioning transplants for several years . - pubmed
Irregular uterine bleeding is a major side effect of long - acting progestogen - only contraceptives in women , and is the primary reason women discontinue their use . - pubmed
In this study , a mouse model of endometrial breakdown was established using a subcutaneous progesterone implant to understand how irregular bleeding begins . - pubmed
The emergence of metastatic disease in cancer patients many years or decades after initial successful treatment of primary tumors is well documented but poorly understood at the molecular level . - pubmed
Predicting surgical outcome in patients with glioblastoma multiforme using pre - operative magnetic resonance imaging : development and preliminary validation of a grading system . - pubmed
A systematic review of the literature was performed to identify features on pre - operative magnetic resonance imaging ( MRI ) that predict the surgical outcome of patients with GBM . - pubmed
To validate this grading system , a retrospective cohort study of all adult patients with supratentorial GBM who underwent surgical resection between the 1 January 2014 and the 31 June 2015 was performed . - pubmed
Comparative Therapeutic Efficacy of 153Sm - EDTMP and 177Lu - EDTMP for Bone Pain Palliation in Patients with Skeletal Metastases : Patients ' Pain Score Analysis and Personalized Dosimetry . - pubmed
INTRODUCTION : The aim of the present study was to compare the therapeutic efficacy of 153Sm - EDTMP and 177Lu - EDTMP in pain palliation in cancer patients with skeletal metastases . - pubmed
MATERIALS AND METHODS : Thirty patients ( 25 M:5 F , mean age : 66.0 + - 14.7 years ) of breast / prostate cancer with documented skeletal metastases were recruited prospectively . - pubmed
Twenty - two patients did not have NVC ( group A ) and 25 had NVC ( group B ) . - pubmed
Side effects may occur more frequently in patients with NVC at the target coordinate when a root entry zone is used , but the subjective symptoms are not always bothersome . - pubmed
This study aimed to investigate agreement among professionals on the phenotype of children with CP based on standardized videos . - pubmed
METHODS : In a prospective , observational pilot study , videos of fifteen CP patients ( 8 boys , mean age 11 + - 5 y ) were rated by three pediatric neurologists , three rehabilitation physicians and three movement disorder specialists . - pubmed
Novirhabdoviruses like the Viral hemorrhagic septicemia virus ( VHSV ) are rhabdoviruses infecting fish . - pubmed
A recombinant virus derived from a virulent VHSV strain in which the NV R116 residue has been replaced by a serine , rVHSVNVR116S , was generated by reverse genetics and used to infect juvenile trout . - pubmed
First report of cutaneous infiltrative lipoma in goldfish Carassius auratus . - pubmed
To our knowledge , this is the first report of cutaneous infiltrative lipoma in goldfish . - pubmed
METHODS : A total of 196 male T2DM patients without medications known to affect bone metabolism or history of bone fracture , aged & gt;=18years were recruited and divided into impaired cognition group and normal cognition group . - pubmed
RBANS total and all indexes scores were also lower in patients with impaired cognition ( all P<0.05 ) . - pubmed
Arthroscopic partial meniscectomy in young patients with symptomatic discoid lateral meniscus : an average 10 - year follow - up study . - pubmed
INTRODUCTION : The aim of this study is to evaluate mid - to - long - term clinical and radiological outcomes after an arthroscopic partial meniscectomy for symptomatic discoid lateral meniscus ( DLM ) in young patients and to determine whether degeneration of the residual meniscus and articular cartilage progresses during the follow - up period using magnetic resonance imaging ( MRI ) . - pubmed
MATERIALS AND METHODS : We retrospectively reviewed patients aged & lt;= 40 years at surgery who underwent arthroscopic partial meniscectomy for symptomatic DLM and were followed up for & gt;= 5 years . - pubmed
CONCLUSIONS : After an arthroscopic partial meniscectomy for symptomatic DLM , unfavorable clinical outcomes were shown in & gt ; 30 % of the patients during a mean follow - up of 10.0 years . - pubmed
Of 4031 patients who underwent IPAA in 1983 - 2014 , 357 developed IPAA - related pelvic sepsis with or without anastomotic dehiscence . - pubmed
Patients with Crohn ' s disease or cancer were excluded . - pubmed
RESULTS : Three hundred and twenty - six patients developing pelvic sepsis had diversion at the time of IPAA ( D group ) and in 31 who developed pelvic sepsis DLI had been omitted ( O group ) . - pubmed
Forty - eight percent of patients from the O group with anastomotic leak underwent reoperation and had a DLI formed at this second procedure versus 12 % in the D group requiring reoperation ( p & lt ; 0.0001 ) . - pubmed
Latently infected transformed cell models have been used to investigate HIV latency ; however , these models can not accurately represent the quiescent cellular environment of primary latently infected cells in vivo For this reason , in vivo humanized murine models have been developed for screening antiviral agents , identifying latently infected T cells , and establishing treatment approaches for HIV research . - pubmed
Therefore , in the present study , we used the HIV - infected hu - NSG mouse to recapitulate the key aspects of HIV infection and pathogenesis in vivo Moreover , we evaluated the ability of HIV - infected human cells isolated from HIV - infected hu - NSG mice on suppressive cART to act as a latent HIV reservoir . - pubmed
IMPORTANCE HIV can establish a stably integrated , nonproductive state of infection at the level of individual cells , known as HIV latency , which is considered a primary barrier to curing HIV . - pubmed
We therefore describe a novel application of the hematopoietic stem cell - transplanted humanized NSG model for dynamically testing antiretroviral treatment , supporting HIV infection , establishing HIV latency in vivo The hu - NSG model could be a facile alternative to humanized bone marrow / liver / thymus or SCID - hu - thy / liv mice in which laborious surgical manipulation and time - consuming human cell reconstitution is required . - pubmed
Materials and Methods : This retrospective study included 48 patients with lung adenocarcinoma , who underwent a contrast - enhanced dual - energy spectral CT scan before treatment ( 53 GGOs in total ) . - pubmed
Effects of Acyclovir and IVIG on Behavioral Outcomes after HSV1 CNS Infection . - pubmed
Respirator support time and ICU stay time of patients in observation group were significantly shorter than those in control group , and the incidence of postoperative complications of patients in the observation group were significantly lower than the control group . - pubmed
Cavernous nerve injury by radiation therapy may potentiate erectile dysfunction in rats . - pubmed
Patients with malignancy were excluded from the study , except those with suspected stage 1 and 2 endometrial carcinoma . - pubmed
Of all , 3.3 % of patients were converted to open surgery ; there was no vascular injury or re - operation . - pubmed
Methods : Twenty patients with iRBD and 22 healthy controls underwent cervical ( cVEMP ) , masseter ( mVEMP ) and ocular ( oVEMP ) VEMP recording . - pubmed
Patients were assessed clinically according to presence of motor as well as non - motor symptoms such as constipation , depression , and hyposmia . - pubmed
Conclusion : VEMPs unveil consistent and extensive brainstem abnormalities in iRBD patients . - pubmed
Successful use of an immune checkpoint inhibitor in a patient with myasthenia gravis in remission . - pubmed
Inflammation , Immunity , and Vaccine Development for the Gastric Pathogen Helicobacter pylori . - pubmed
Clinical trials employing many of the strategies used in rodents for oral immunization including the use of a mucosal adjuvant such as Escherichia coli LT or delivery by attenuated enteric bacteria have failed to limit H. - pubmed
Antioxidants protect against diabetes by improving glucose homeostasis in mouse models of inducible insulin resistance and obesity . - pubmed
In healthy chow - fed animals as well as in morbidly obese mice , this diabetic phase could be reversed within a few weeks . - pubmed
In ob / ob mice , antioxidants rescued both hyperglycaemia and hyperphagia . - pubmed
Chikungunya virus ( CHIKV ) , a re - emerging mosquito - borne arbovirus , has caused millions of cases of severe , often chronic arthralgia during recent outbreaks . - pubmed
Recent outbreaks have been enhanced by mutations that adapt CHIKV for more efficient infection of Ae . - pubmed
Three weeks after the injections the rats were exposed to a 7 - day intermittent hypoxia protocol . - pubmed
MATERIALS AND METHODS : Eighty subjects were prospectively enrolled in the study : 35 subjects with clinically confirmed iNPH and 45 matched healthy controls ( HC ) . - pubmed
Methods : 120 females aged > = 25 years were evaluated for acne , hirsutism and androgenetic alopecia . - pubmed
Results : A 26 - year - old woman with a past medical history of obesity , prediabetes , and polycystic ovary syndrome presented with worsening hirsutism and markedly elevated testosterone levels . - pubmed
Given the broad changes in adaptive immunity , including memory T cell expansion , and rising prevalence of diabetes in the HIV population , we assessed whether similar relationships were present in persons with HIV ( PWH ) . - pubmed
Dolutegravir - associated hyperglycaemia in patients with HIV . - pubmed
Approximately 60 % of all human pathogens and 75 % of emerging infectious diseases are zoonotic ( of animal origin ) . - pubmed
In this study , 19 important zoonotic diseases were reported among Iranian camels including listeriosis , leptospirosis , plague , Q fever , brucellosis , campylobacteriosis , tuberculosis , pasteurellosis , clostridiosis , salmonellosis , Escherichia coli infections , rabies , camelpox , Middle East respiratory syndrome coronavirus , Crimean - Congo haemorrhagic fever , echinococcosis , cryptosporidiosis , toxoplasmosis and dermatophytosis , most of which belong to bacterial , viral , parasitic and fungal pathogens , respectively . - pubmed
Results show that camels are one of the most important sources of infections and diseases in human ; therefore , continuous monitoring and inspection programs are necessary to prevent the outbreak of zoonotic diseases caused by this animal in humans . - pubmed
Pneumonia caused by 2019 - nCoV infection has been reported in Wuhan since December 2019 , and spread rapidly across the country . - pubmed
Cytomegalovirus Proctitis in a Patient with Chronic Lymphocytic Leukemia on Ibrutinib Therapy : A Case Report . - pubmed
Subsequent colonoscopy revealed a circumferential rectal ulcer ; biopsy of the rectal ulcer was positive for CMV immunostain . - pubmed
Baseline prevalence and correlates of HIV and HCV infection among people who inject drugs accessing a syringe services program ; Miami , FL . - pubmed
BACKGROUND : Blood - borne viral infections , such as HIV and hepatitis C ( HCV ) , are common infections among people who inject drugs ( PWID ) . - pubmed
This study aims to determine the prevalence of HIV and HCV infection among PWID accessing the first legal syringe services program ( SSP ) in the state of Florida , along with examining baseline correlates of HIV and HCV infection . - pubmed
Bivariate and multivariable logistic regression models were used to assess correlates of baseline HCV and HIV infection independently . - pubmed
RESULTS : Overall prevalence for HCV and HIV infection were 44.4 % and 10.2 % , respectively . - pubmed
Elevated ICP in two patients , one related to progressive mass effect from infarctions , and the other to dialysis , correlated with generalized slowing and attenuation of fast activity up to 24 hours before clinical deterioration , leading to diffuse suppression . - pubmed
Two patients with intraventricular hemorrhage had cyclic patterns at ~1 per minute and ~6 per minute ( similar frequency to described frequency of Lundberg B and C waves , respectively ) . - pubmed
METHODS : The prospective observational cohort study was conducted at Bakirkoy Dr. Sadi Konuk Training and Research Hospital , Istanbul , Turkey , from December 1 , 2015,to March 1 , 2016 , and comprised suspected pneumonia patients aged > 18 years . - pubmed
Patients in whom pneumonia was detected in the scan underwent thorax ulstasonography according to Bedside Lung Ultrasound in Emergency protocol . - pubmed
Patients should be regularly evaluated for bleeding risks and thrombotic complications . - pubmed
Treatments for inflammatory bowel disease ( IBD ) largely involve lifelong drug prescriptions or surgical intervention that can lead to poor quality of life for patients . - pubmed
The introduction of beta - CD and PEG / beta - CD polypseudorotaxane on SiO2 magnetic nanoparticles ( SOMNP ) limited particle intramuscular dispersion after being injected into mouse gastrocnemius muscle ( GN ) , which led to the prolonged local inflammation and muscle toxicity by CDMNP and CDMNP - PEG - CD . - pubmed
A patient with cerebral malaria complicated by full - blown DIC , after failing to respond to other forms of treatment , was successfully treated by exchange transfusion . - pubmed
Modification of hepatotoxic effects of aflatoxin B1 in rabbits by immunization . - pubmed
[ Preoperative preparation of patients with dysphagia ] . - pubmed
Fifty - eight continent women operated on for genito - urinary prolapse , underwent urethrocystography prior to and 3 months following surgery . - pubmed
The value of dobutamine infusion for thallium myocardial perfusion tomography was assessed in 50 patients with exertional chest pain undergoing coronary arteriography . - pubmed
Thirty - nine of 40 patients with coronary artery disease had a reversible perfusion defect demonstrated by dobutamine thallium tomography ( sensitivity 97 % ) and 8 of 10 patients with normal coronary arteries had normal myocardial perfusion ( specificity 80 % ) . - pubmed
Dobutamine infusion was well tolerated in all patients , including six with asthma . - pubmed
Clinical significance of the " palpable mass " in patients with muscle - infiltrating bladder cancer undergoing cystectomy after pre - operative radiotherapy . - pubmed
After a median time of 41 months , 62 patients were alive ; 51 had died from recurrent bladder cancer and 19 from intercurrent disease without recurrence of their malignancy . - pubmed
Distant metastases developed in 40 patients , accompanied in 5 cases by local recurrence . - pubmed
Local recurrence was the first sign of relapse in 11 patients . - pubmed
In 3 patients the localisation of the relapse remained unknown . - pubmed
However , the prognostic value of stage reduction was statistically significant only in patients with palpable bladder tumours . - pubmed
A 13 year old girl with PXA in the right occipitoparietal region is reported . - pubmed
Photochemical damage to the carotid artery of rats produces microemboli to the brain , resulting in cavitary lesions resembling lacunes in humans . - pubmed
This protein also shows a potent anti - tumour activity in vivo in animal tumour models and is currently undergoing Phase I human clinical trials in cancer patient volunteers . - pubmed
Release of substance - P - like immunoreactivity in dog paw lymph after scalding injury . - pubmed
Experimental infection of squirrels Sciurus vulgaris by monkey pox virus . - pubmed
[ Campylobacter pyloridis in duodenal ulcer ] . - pubmed
Campylobacter pyloridis ( CP ) were detected in 83 % of the cases by histologic investigation of gastric and duodenal mucosa biopsy specimens obtained from patients with duodenal ulcers . - pubmed
Although conventional antiulcer treatment reduces CP dissemination , the bacteria are not eliminated in most cases , which might be a cause of peptic ulcer relapses . - pubmed
We describe three 14 - year - old boys who developed synovial fluid eosinophilia associated with Lyme disease . - pubmed
[ Preliminary study on cytogenetics in patients with oral lichen planus ] . - pubmed
Beagle dogs 3 - 7 years old were ovariectomized ( n = 9 ) or sham operated ( n = 6 ) and followed for 48 weeks with measurements of body weight , tibial shaft bone mineral content ( BMC ) , and serum biochemistry . - pubmed
10 patients are alive and well 50 - 760 days after transplantation , without any signs of recurrence and partly without immunosuppressive therapy . - pubmed
Two patients died , one due to relapse of the leukaemia , and one as a result of CMV interstitial pneumonia . - pubmed
Graft versus host disease was seen in 6 of the 12 patients . - pubmed
The incidence of idiopathic interstitial pneumonia in our group of patients was low ( two cases ) . - pubmed
After removal of all clinically detectable tumour tissue by maximal surgical therapy in 5 patients , residual systemic metastases were treated by means of total body irradiation and high - dose cyclophosphamide , followed by autologous bone marrow transplantation with curative intention . - pubmed
Relapse occurred in 4 patients between day 100 and 720 after BMT bone marrow transplantation . - pubmed
Only one patient remains without sign of relapse . - pubmed
Management of simple depressed skull fractures in children . - pubmed
The results showed that lambs on a low protein diet were less able to withstand the pathogenic effects of infection with 350 H. - pubmed
[ Modifications by some vasoactive drugs of the effects of an encephalic ischemic anoxia in cats ] . - pubmed
The permissiveness of differentiating mouse muscle - cell cultures to infection by group A coxsackievirus types 1 and 5 . - pubmed
[ Experimental reproduction of myocardial infarcts with arrhythmias in rabbits ] . - pubmed
Manual dilatation of the anus was carried out on 50 unpremedicated outpatients under propanidid , nitrous oxide , and halothane anaesthesia with E.C.G.monitoring . - pubmed
Geometrical illusions and the response of neurones in the cat 's visual cortex to angle patterns . - pubmed
This neural distortion of sensory information seems adequate to explain the well known illusions of orientation that are associated with human perception of patterns containing acute angles . - pubmed
Massive haemorrhage from vaginal varicose veins in patient with liver cirrhosis . - pubmed
These levels rose again when the patient developed liver metastases but normalized during chemotherapy , never to rise again despite the appearance of cervical lymph node metastasis . - pubmed
[ Treatment of traumatic vitreal hemorrhages in Rh - positive patients with intravitreal injection of anti - Rh antibodies ] . - pubmed
In other studies , intravenous administration of PGI2 ( 25 or 75 ng / kg / min ) , indomethacin ( 4 mg / kg ) , or indomethacin ( 4 mg / kg ) plus PGI2 ( 25 ng / kg / min ) failed to reverse angiographic delayed vasospasm produced in vivo in the canine basilar artery by an intracisternal injection of blood . - pubmed
The joint disease in patients with erythema nodosum was essentially the same as that seen in patients who did not develop skin lesions . - pubmed
A polypeptide which inhibits the growth of human carcinoma cells has been characterized from Novikoff rat ascites fluid . - pubmed
This factor inhibited the anchorage independent growth of the more differentiated human colon carcinoma cell lines but did not affect the less differentiated carcinoma cells . - pubmed
Double - blind comparative clinical trial of carprofen versus diclofenac - Na in patients with coxarthrosis . - pubmed
A randomized double - blind trial was performed in 50 patients with moderate to severe coxarthrosis , 25 receiving 300 mg carprofen and 25 150 mg diclofenac - Na daily in 3 doses . - pubmed
Efficacy of ( E )- 5 -( 2 - bromovinyl )- 2 '- deoxyuridine in the treatment of experimental herpes simplex virus encephalitis in mice . - pubmed
Systemic treatment of mice with ( E )- 5 -( 2 - bromovinyl )- 2 '- deoxyuridine ( BVDU ) showed a significant therapeutic efficacy against herpes simplex type 1 virus ( HSV-1 ) encephalitis . - pubmed
Furthermore , at doses of 300 - 500 mg / kg per day BVDU prevented the establishment of latent virus infection in the trigeminal ganglia following intracerebral HSV-1 inoculation . - pubmed
A patient who had MF with ulcerating cutaneous nodules is presented herein . - pubmed
Transgenic mouse models in studies of skeletal disorders . - pubmed
Studies of mutations in mice and humans are identifying molecular defects in a number of osteochondrodysplasias . - pubmed
High frequency of thyroid dysfunction in patients with vitiligo . - pubmed
This study was undertaken to determine the frequency and type of thyroid disease in 35 consecutive patients admitted because of vitiligo compared with a matched control group . - pubmed
One or more signs of thyroid disease was demonstrated in 15 out of 35 patients ( 43 % ) with vitiligo , as compared to 7 out of 35 ( 20 % ) in the matched control group ( p = 0.04 ) . - pubmed
Thyroid dysfunction - 6 patients with hyperthyroidism and 2 with hypothyroidism - was found in 8 out of 35 patients , as compared to no patient in the control group ( p = 0.003 ) . - pubmed
There appears to be an increased frequency of clinical as well as subclinical thyroid disease in patients with vitiligo . - pubmed
Our findings support the theory of vitiligo being an autoimmune disease and indicate a need for screening vitiligo patients for thyroid disease . - pubmed
Three patients with S - I radiculopathy leading to ipsilateral neurogenic calf hypertrophy following hernia nuclei pulposi are described , two men of 79 and 78 years old and a woman of 46 years . - pubmed
We investigated weight gain and clinical course of 14 patients with cystic fibrosis ( CF ) , aged 7 to 23 years , who received long - term nocturnal supplemental feedings by means of percutaneous endoscopic gastrostomies ( PEGs ) . - pubmed
We conclude that nocturnal PEG feedings of malnourished patients with CF improve nutritional status and lung function without major side effects . - pubmed
This study has concluded that TNP can be used for spinal cord monitoring , especially in patients with thoracolumbar disorders . - pubmed
In a randomized 6 - week trial comparing fluoxetine with placebo , the Medical Outcomes Study 36 - Item Short - Form Health Status Survey ( SF-36 ) scales were used to measure the effects of treatment on functional health and well - being among elderly ( age & gt ; or = 60 years ) outpatients with major depression . - pubmed
Compared with national norms for individuals over age 60 , study patients before treatment exhibited baseline decrements on the following SF-36 scales : mental health , role limitations due to emotional problems , social functioning , vitality , role limitations due to physical problems , and bodily pain . - pubmed
Nosocomial septicemias due to methicillin - resistant staphylococcus aureus and Pseudomonas aeruginosa in a university hospital over a 12 - year period -- the same intractable infections . - pubmed
Clinical features of nosocomial bacteremias due to methicillin - resistant Staphylococcus aureus ( MRSA ) ( M group , n = 71 ) and Pseudomonas aeruginosa ( P group , n = 25 ) in a university hospital during 1982 - 1993 were retrospectively analyzed . - pubmed
We studied 105 subjects who fulfilled the DSM - III - R criteria for a current major depressive episode and 41 volunteers with no current mental disorder . - pubmed
The relationship between these two variables and treatment outcome was particularly strong in depressed male subjects who were receiving desipramine , for whom they accounted for 36 % of the variance in treatment outcome . - pubmed
Although this finding requires replication , it is consistent with other reports of the usefulness of thyroid - axis indices measured at different times of day in depressed patients . - pubmed
We reported a 71 - year - old male patient with multiple liver recurrence of hepatocellular carcinoma , who responded to arterial infusion chemotherapy using CDDP and 5 - FU . - pubmed
[ The dynamic laboratory indices of patients with insulin - dependent diabetes mellitus during health - resort treatment ] . - pubmed
The immunological status was assessed in 100 patients with insulin - dependent diabetes mellitus before and after treatment in sanatorium . - pubmed
Canine cystine urolithiasis . - pubmed
In some dogs , the severity of cystinuria may decline with advancing age . - pubmed
OBJECTIVE : In patients with severe aortic stenosis , we studied the impact of gender on preoperative left ventricular geometry and function , as well as on early postoperative mortality and morbidity . - pubmed
RESULTS : The patients had severe aortic stenosis and the mean pressure gradients were similar in females and males . - pubmed
The ejection fraction was similar in females ( 55+/-14 % ) and males ( 55+/-13 % ) , and patients of both sexes had significantly lower stroke volume and cardiac index than healthy controls . - pubmed
The eczema in 3 of 4 patients who stopped smoking improved . - pubmed
This study evaluates postoperative patient comfort and satisfaction of 100 unilateral inguinal hernia repairs performed by Shouldice procedure with steel wire and local anesthesia . - pubmed
Only 7 of 61 ( 11.5 % ) patients had ketoacidosis at first presentation . - pubmed
Five patients had associated autoimmune thyroid disease and 10 ( 16.7 % ) patients had family history of diabetes in first - degree relatives . - pubmed
Movement related cortical source for elbow flexion in patients with branchial plexus injury after intercostal - musculocutaneous nerve crossing . - pubmed
Nine patients with brachial plexus injury whose transected musculo - cutaneous nerves had been sutured with intercostal nerves were examined and the relationship between flexion of the operated elbow and the respiratory movement were shown . - pubmed
It is anticipated that future research in these areas will identify optimal treatment strategies for elderly ESRD patients starting on dialysis and improve patient outcomes . - pubmed
Antidepressants are not only effective in younger adults but also in older persons with depression . - pubmed
Such findings may also explain the observed high clinical incidence of vascular calcification in the osteoporotic patient population . - pubmed
Effect of Withania somnifera on 20 - methylcholanthrene induced fibrosarcoma . - pubmed
Administration of an extract from the root of the plant Withania somnifera ( 20mg / dose / animal i.p ) was found to inhibit the 20 - methylcholanthrene induced sarcoma development in mice and increase the life span of tumour bearing animals . - pubmed
Withania could increase the GSH level ( 7.7 micromoles / mg protein ) which was lowered in control tumour bearing animals ( 3.96 micromoles / mg protein ) . - pubmed
All the animals in the control group developed sarcoma by the 80th day of carcinogen administration . - pubmed
Only 3 animals in the Withania treated group developed sarcoma by the 105th day . - pubmed
These results indicate that Withania could inhibit 20 - methylcholanthrene induced sarcoma development in mice . - pubmed
[ The effects of percutaneous endoscopic gastrostomy feeding in patients with swallowing disturbance ] . - pubmed
I conclude that PEG will become the first choice for improving nutrition in patients with dysphasia and will contribute to continuous enteral nutrition for home care . - pubmed
Immunohistochemically we examined normal - appearing intranodal thyroid tissue in four patients who did not show evidence of papillary carcinoma histologically or clinically . - pubmed
[ Autonomic neuropathy in uremic patients ] . - pubmed
In patients with intermittent claudication , the phosphorus - creatinine index at peak of exercise was decreased by 26.1 % ( p & lt ; 0.001 ) , in patients with varicose disease -- by 25.6 % ( p & lt ; 0.001 ) , in patients with chronic heart failure by 8 % ( p & lt ; 0.001 ) . - pubmed
This article reviews the diagnosis and management of clinical disorders of potassium balance , with particular attention to the critically ill patient . - pubmed
[ Changes of HBV - DNA in patients with chronic hepatitis B -- relation to prognosis and therapy ] . - pubmed
STUDY DESIGN : During a 22 - year period ( July 1979 - June 2001 ) , nipple discharge from nine males with breast lesions were examined . - pubmed
RESULTS : In the three patients with florid gynecomastia the smears were cellular , with numerous benign ductal cells and papillary fragments along with foam cells and inflammatory cells . - pubmed
PURPOSE : Randomized trials in fluorouracil ( FU)-refractory colorectal cancer demonstrate significant survival advantages for patients receiving irinotecan . - pubmed
Grade 3/4 diarrhea occurred in 36 % of patients treated weekly and in 19 % of those treated once every 3 weeks ( P = .002 ) . - pubmed
Grade 3/4 neutropenia occurred in 29 % of patients treated weekly and 34 % of those treated once every 3 weeks ( P = .35 ) . - pubmed
CONCLUSION : Irinotecan schedules of weekly and of once every 3 weeks demonstrated similar efficacy and quality of life in patients with FU - refractory , metastatic colorectal cancer . - pubmed
The authors analyzed reports from randomized controlled trials to compare suicide rates among depressed patients assigned to an SSRI , other antidepressants , or placebo . - pubmed
RESULTS : Of 48,277 depressed patients participating in the trials , 77 committed suicide . - pubmed
A bioassay of the phenylurea herbicide fluometuron for possible carcinogenicity was conducted by administering the test chemical in feed to F344 rats and B6C3F1 mice . - pubmed
Splenomegaly observed in rats in the subchronic studies influenced selection of the doses for the chronic study ; however , no splenic effects were observed in the chronic study . - pubmed
Mean body weights of the dosed groups of male and female rats and mice were essentially the same as those of the corresponding control groups . - pubmed
Similarities between mean body weights and survival between dosed and control animals in thechronic study suggest that these animals could have tolerated higher doses . - pubmed
Incidences of hepatocellular carcinomas or adenomas in male mice were dose related , and the incidence in the high - dose group was marginally higher than that in the corresponding matched controls or pooled controls from concurrent studies . - pubmed
Equivocal results were obtained for male B6C3F1 mice which may have had an increased incidence of hepatocellular tumors . - pubmed
Because of the equivocal findings and because both rats and mice may have been able to tolerate higher doses , it is concluded that additional testing of fluometuron for carcinogenicity is warranted . - pubmed
We report a case of a boy aged 3 years and 1 month with a history of oral thrush , chronic diarrhea , skin abscesses , multiple small joints osteomyelitis , and multiple liver abscesses since 2 months of age . - pubmed
Two episodes of aspergillosis with severe aspergillus lung empyema and life - threatening Klebsiella pneumoniae infections were noted in the first 2 years of life despite long - term prophylaxis with trimethoprim - sulfamethoxazole and itraconazole . - pubmed
Patients in leg ulcer services with leg ulceration were screened for inclusion in this trial . - pubmed
Patients with arterial disease ( ankle brachial pressure index & lt ; 0.8 ) and causes of ulceration other than venous disease were excluded . - pubmed
For patients with bilateral ulceration , the limb with the larger area of ulceration was studied . - pubmed
In all , 156 patients met entry criteria and were randomized from the 12 clinical centers with median ( range ) ulcer size of 4.33 ( 0.33 - 123.10 ) cm(2 ) . - pubmed
Of the 74 patients randomized to the four - layer bandage , 51(69 % ) had ulcer closure on treatment compared with 60/82 ( 73 % ) on the cohesive short - stretch system . - pubmed
The tumor locations were in the uncinate process in 4 ( 40 % ) , in the head and neck in 2 ( 20 % ) , in the body in 1 ( 10 % ) , and in the tail in 3 ( 30 % ) patients . - pubmed
During dynamic CT in 8 patients , 6 tumors showed early arterial ( EA ) enhancement and persisted into the portal venous ( PV ) phase , whereas the other 2 tumors revealed enhancement in the EA phase and washout in PV phase . - pubmed
The complexity of the diagnostics of this disease makes it necessary to search for new methods ; for this reason immunity in CFA patients must be studied . - pubmed
This made it possible to propose to use these reactions for confirming the diagnosis of CFA and suggested the probable role of M. - pubmed
Six patients with established nonunion of the humeral shaft underwent this technique . - pubmed
Bilateral retinal detachment was present in 12 ( 10.8 % ) ; 51 ( 46 % ) patients had some form of bilateral ocular pathology at initial presentation . - pubmed
CASE : This 30 - year - old woman had an accessory ovarian tumor attached to the infundibulum of the right fallopian tube which was solid and gross pathologically and microscopically showed the appearances of steroid cell tumor , NOS , a benign entity . - pubmed
[ Phototactic behavior of Daphnia carinata as an indicator of chromium biotoxicity ] . - pubmed
The study on the phototactic behavior of Daphnia carinata clone Dc42 as an indicator of chromium biotoxicity showed that the phototaxis inhibition ratio ( Rpi ) of D. - pubmed
METHODS : Corneal asphericity and r(o ) were calculated by using corneal topography data on 643 children ( 72 myopes , 370 emmetropes , and 201 hyperopes ) , ages 6 to 15 years , who participated in the Orinda Longitudinal Study of Myopia ( OLSM ) during 1991 . - pubmed
Relationship between creatinine clearance and plasma homocysteine levels in predialytic chronic renal failure patients . - pubmed
BACKGROUND : Trichobezoars represent 55 % of human bezoars . - pubmed
OBJECTIVE : To study the clinical features , diagnostic methodology and treatment in patients with trichobezoars . - pubmed
RESULTS : All patients had an epigastric mass , dyspepsia , vomiting , and weight loss of 5 to 25 kg , without pain . - pubmed
A gadolinium - enhanced " one - stop shop '' magnetic resonance angiography was performed within 24 hours of completed diagnostic imaging work - up for pulmonary embolism and deep venous thrombosis in 20 patients . - pubmed
The " one - stop shop '' imaging procedure using gadolinium - enhanced magnetic resonance angiography was feasible and proved to offer a reliable and rapid diagnostic approach in thromboembolic disease , sparing patients ' exposure to ionizing radiation and iodinated contrast media . - pubmed
Probability of axillary lymph node metastasis when sentinel lymph node biopsy is negative in women with clinically node negative breast cancer : a Bayesian approach . - pubmed
METHODS : Patients admitted with West syndrome in Children 's Hospital , Islamabad , between January 1995 and December 2001 were included in the analysis . - pubmed
Seventy - two patients were given oral prednisolone , 51 responded and 17 remained spasms free after oral steroids were stopped . - pubmed
We report the response to pacing and pharmacologic maneuvers performed in patients with stable focal ATs after segmental PV isolation . - pubmed
METHODS : Patients with persistent left AT after cessation of antiarrhythmic drug therapy presented for mapping and ablation . - pubmed
RESULTS : Five patients ( 3 men and 2 women ; age 65 + /- 10 years ) had focal left AT that persisted in response to pacing maneuvers . - pubmed
Four patients had ATs ( cycle length 265 + /- 18 ms ) that demonstrated focal areas of early activation at the septal aspect of the right lower ( 3 patients ) or right upper ( 1 patient ) PV ostium . - pubmed
Adenosine was infused with transient AV block and no change to the tachycardia cycle length in three patients . - pubmed
METHODS : Fifty - four breast cancer patients with 57 breast lesions underwent 2 sequential PET scans ( dual - time - point imaging ) . - pubmed
In this study , the possible involvement of these two hormones in B - deficiency - induced changes in apical dominance was investigated by applying B or the synthetic CK CPPU to the shoot apex of pea plants grown in nutrient solution without B supply . - pubmed
METHODS : Secondary analyses of three randomized , double - blind , placebo - controlled multicenter studies in stage 3 and 4 chronic kidney disease ( CKD ) patients with SHPT were performed to compare three times per week ( TIW ) with QD dosing of paricalcitol . - pubmed
In CKD patients , baseline data were similar between the TIW studies ( n = 72 , paricalcitol ; n = 73 , placebo ) and QD studies ( n = 35 , paricalcitol ; n = 40 , placebo ) . - pubmed
BACKGROUND AND PURPOSE : To determine the sleep response to caffeine in individuals vulnerable to stress - related sleep disturbance as measured by polysomnography . - pubmed
PATIENTS AND METHODS : Eleven healthy individuals without insomnia scoring low ( 4 women , mean age=32.64+/-15.46 years ) and 10 healthy individuals also without insomnia scoring high ( 6 women , mean age=34.20+/-13.73 years ) on a measure of vulnerability to stress - related sleep disturbance were studied in a laboratory protocol . - pubmed
Importantly , individuals reporting vulnerability to stress - related sleep disturbance had significantly prolonged latency to persistent sleep in response to the caffeine challenge ( interaction ; P<0.05 ) . - pubmed
This finding provides further support for generalized trait vulnerability by demonstrating a sleep disturbance to a wake - promoting pharmacological challenge in specific a priori identified individuals . - pubmed
Use of selamectin for the treatment of psoroptic and sarcoptic mite infestation in rabbits . - pubmed
A total of 42 New Zealand rabbits with psoroptic mange and 37 Angora rabbits with sarcoptic mange were used in the present study . - pubmed
We present foreign body granulomas induced by activated charcoal from intraperitoneal chemotherapy and mimicked peritoneal metastases in the patients with gastric cancer . - pubmed
BACKGROUND : The mechanism underlying nocturnal sudden death in patients with MSA remains unclear . - pubmed
Fiberoptic laryngoscopy during wakefulness showed that 3 ( 14 % ) of the 21 patients exhibited vocal cord abductor paralysis , and laryngoscopy under anesthesia showed that 9 ( 45 % ) of 20 patients exhibited vocal cord abductor paralysis . - pubmed
Laryngoscopy under anesthesia also revealed that 11 ( 55 % ) of 20 patients showed upper airway obstruction in places other than the vocal cords , including obstruction at the base of the tongue or soft palate . - pubmed
CONCLUSIONS : We observed daytime hypoxemia with an increased alveolar - arterial oxygen gradient , Cheyne - Stokes respiration , and novel abnormal laryngopharyngeal movements in patients with MSA . - pubmed
Complete clinical and virological remission of refractory HIV - related Kaposi ' s sarcoma with pegylated interferon alpha . - pubmed
Improved survival for children with parameningeal rhabdomyosarcoma : results from the AIEOP soft tissue sarcoma committee . - pubmed
PROCEDURE : We reviewed 109 children with non - metastatic PM - RMS enrolled in the Italian RMS79 , RMS88 and RMS96 protocols over a 24 - year period . - pubmed
CONCLUSION : Outcome in PM - RMS patients enrolled in three consecutive Italian protocols has progressively improved , as a result of intensive chemotherapy , delayed surgery and , possibly , HART , though improved imaging and radiotherapeutic tools may have had a role as well . - pubmed
Streptococcus intermedius is found in biofilms on teeth and as a commensal member of the gastrointestinal and urinary floras , but may also be associated with deep - seated purulent infections and infective endocarditis . - pubmed
The obtained data allow us to suppose that the development of oxidative stress under demyelination conditions is a result of strong metabolic disorders and decrease of antioxidant defence in the patients during the disease development . - pubmed
The necessity of individual approaches for antioxidant therapy of patients with MS is discussed . - pubmed
Continuous oral or intramuscular medroxyprogesterone acetate versus the levonorgestrel releasing intrauterine system in the treatment of perimenopausal menorrhagia : a randomized , prospective , controlled clinical trial in female smokers . - pubmed
DESIGN : One hundred thirty - two women with menorrhagia were included in this prospective , randomized , comparative trial . - pubmed
An avipoxvirus infection in a goshawk ( Accipiter gentilis ) . - pubmed
This report describes the nodular lesions found on a young , male European goshawk ( Accipiter gentilis ) which were found to be poxvirus lesions in conjunction with a Staphylococcus aureus infection . - pubmed
To our knowledge the goshawk has been reported as being susceptible to avipoxvirus infections , but no clinical reports have been published concerning this species . - pubmed
Regional endocardial left atrial voltage and electrogram fractionation in patients with atrial fibrillation . - pubmed
This study aimed at investigating endocardial voltage in different regions of the left atrium in patients with atrial fibrillation ( AF ) . - pubmed
METHODS AND RESULTS : Thirty - six patients ( aged 56 + /- 7 years , 10 female ) scheduled for circumferential ablation for paroxysmal AF were studied . - pubmed
CONCLUSION : During AF , the posterior wall displays significantly higher voltage and electrogram fractionation compared with other parts of the left atrial endocardium outside the antra of both pulmonary veins in patients with paroxysmal AF . - pubmed
[ Characteristics of postoperative ectopic junctional ectopic tachycardia in children with congenital heart disease ] . - pubmed
BACKGROUND : As more patients undergo diagnostic thyroid surgery , the development of posthemithyroidectomy hypothyroidism is becoming a major concern . - pubmed
RESULTS : Biochemical hypothyroidism developed in 37 patients ( 36.6 % ) . - pubmed
A patient with chronic hemodialysis - dependent end - stage renal disease presenting with mild dyspnea on exertion and a harsh systolic murmur . - pubmed
The unilateral ischemia hindlimb model was made with 12 Lewis rats . - pubmed
Cardiovascular disease is a leading cause of death in the United States and across the world , and better therapies are constantly being sought to improve patient outcomes . - pubmed
, diabetes , lipid management , and weight control ) , but it also has been shown in animal studies to have positive cardiac effects irrespective of its effects on glucose control and weight loss . - pubmed
Chondrocyte death and cartilage degradation after autologous osteochondral transplantation surgery in a rabbit model . - pubmed
Novel therapeutic strategies targeting vascular redox in human atherosclerosis . - pubmed
RADAR - A randomised , multi - centre , prospective study comparing best medical treatment versus best medical treatment plus renal artery stenting in patients with haemodynamically relevant atherosclerotic renal artery stenosis . - pubmed
BACKGROUND : Prospective , international , multi - centre , randomised ( 1:1 ) trial to evaluate the clinical impact of percutaneous transluminal renal artery stenting ( PTRAS ) on the impaired renal function measured by the estimated glomerular filtration rate ( eGFR ) in patients with haemodynamically significant atherosclerotic renal artery stenosis . - pubmed
Biopsy - proven prostatic malignancy was detected in 20 patients . - pubmed
Using recombinant tetanus toxin H(C ) fragment ( rTT - H(C ) ) as carrier , we prepared multimeric bivalent immunogens featuring the synthetic hexasaccharide fragment of O - PS of Vibrio cholerae O:1 , serotype Ogawa , in combination with either the synthetic hexasaccharide fragment of O - PS of Vibrio cholerae O:1 , serotype Inaba , or a synthetic disaccharide tetrapeptide peptidoglycan fragment as adjuvant . - pubmed
[ Bilateral cerebellopontine angle lipoma in an asymptomatic patient : a case report ] . - pubmed
MATERIAL AND METHODS : 22 patients with intellectual disability , congenital anomalies and dysmorphic features were analysed . - pubmed
Effect of prophylactic trochanteric epiphyseodesis in older children with Perthes ' disease . - pubmed
To evaluate the effect of prophylactic epiphyseodesis of the greater trochanter in Perthes ' disease , 62 children with unilateral Perthes ' disease who underwent trochanteric epiphyseodesis combined with varus osteotomy of the femur during the active stage of the disease ( mean age at surgery : 8.4 y ) and 20 controls were followed up until skeletal maturity . - pubmed
In the infection - induced cells , viral RNA was degraded rapidly , and a cytosol extract prepared from the infected cells showed RNA degradation activity specific for ToMV- or GFP - related sequences . - pubmed
The inducible virus infection system may provide a method for biochemical analysis of antiviral RNA silencing and silencing suppression by ToMV . - pubmed
A / C magnetic hyperthermia of melanoma mediated by iron ( 0 )/ iron oxide core / shell magnetic nanoparticles : a mouse study . - pubmed
Aim of the study was assessment of prevalence of HPS in cirrhotic patients qualified to liver transplantation and determination of clinical risk factors of this syndrome . - pubmed
MATERIAL AND METHODS : The study involved 30 patients with advanced liver cirrhosis of different etiology , qualified to liver transplantation . - pubmed
RESULTS : We did not find symptomatic HPS in the investigated group , but 2 patients ( 6.6 % ) with alcoholic cirrhosis showed arterio - venous intrapulmonary shunt . - pubmed
In a randomized , double - blind , placebo - controlled , multinational trial in patients with locally advanced or metastatic renal cell carcinoma , the median progression - free survival ( PFS ) of patients who were treated with pazopanib 800 mg once daily was significantly longer than that of placebo recipients ( 9.2 vs 4.2 months ; hazard ratio 0.46 [ 95 % CI 0.34 , 0.62 ] ) . - pubmed
Oral pazopanib had an acceptable tolerability profile in patients with advanced renal cell carcinoma . - pubmed
This opinion piece explores an " ablate and wait " strategy for improving the 5 - year recurrence - free outcome of liver transplantation in patients with hepatocellular carcinoma . - pubmed
Simple non - invasive fibrosis scoring systems can reliably exclude advanced fibrosis in patients with non - alcoholic fatty liver disease . - pubmed
BACKGROUND : Accurate evaluation of liver fibrosis in patients with non - alcoholic fatty liver disease ( NAFLD ) is important to identify patients who may develop complications . - pubmed
The aim of this study was to compare the diagnostic performance of simple non - invasive tests in identifying advanced fibrosis among patients with biopsy - proven NAFLD . - pubmed
METHODS : Consecutive patients with biopsy proven NAFLD were recruited from the Newcastle Hospitals Fatty Liver Clinic from 2003 to 2009 . - pubmed
93 patients ( 64 % ) had non - alcoholic steatohepatitis . - pubmed
METHODS : We describe a case of a 28 - year - old male who presented with intractable binocular diplopia , which was relieved with a corneal tattoo . - pubmed
Specific mechanical pain hypersensitivity over peripheral nerve trunks in women with either unilateral epicondylalgia or carpal tunnel syndrome . - pubmed
OBJECTIVE : To investigate if pressure pain sensitivity is related to specific nerve trunks in the upper extremity of patients with either unilateral lateral epicondylalgia ( LE ) or carpal tunnel syndrome ( CTS ) . - pubmed
BACKGROUND : In the clinical setting , patients with LE tend to exhibit radial nerve trunk tenderness , whereas patients with CTS exhibit median nerve tenderness . - pubmed
METHODS : Sixteen women with unilateral LE ( mean+-SD age , 43 + -7 years ) , 17 women with unilateral CTS ( 43 + -6 years ) , and 17 healthy women ( 43 + -6 years ) were included in this study . - pubmed
Additionally , radial ( P<.001 ) and ulnar ( P=.005 ) nerves were more sensitive bilaterally in patients with LE than in patients with CTS . - pubmed
The median nerve was more sensitive bilaterally in patients with CTS than patients with LE ( P=.002 ) . - pubmed
CONCLUSIONS : Bilateral mechanical nerve pain hypersensitivity is related to specific and particular nerve trunks in women with either unilateral LE or CTS . - pubmed
Our results suggest the presence of central and peripheral sensitization mechanisms in individuals with either LE or CTS . - pubmed
Identifying neurobiological predictors of response to antipsychotics in patients with schizophrenia is a critical goal of translational psychiatry . - pubmed
In this study , we sought to identify magnetic resonance ( MR ) imaging measures of the brain that predict treatment response in patients experiencing a first - episode of schizophrenia . - pubmed
Structural MR imaging scans were acquired in 39 patients experiencing a first - episode of schizophrenia with minimal or no prior exposure to antipsychotics participating in a double - blind 16 - week clinical trial comparing the efficacy of risperidone vs olanzapine . - pubmed
Our findings are consistent with the hypothesis that plasticity and cortical thickness may be more preserved in responders and that MR imaging may assist in the prediction of antipsychotic drug response in patients experiencing a first - episode of schizophrenia . - pubmed
Affected patients are susceptible to severe , life - threatening bacterial and fungal infections and excessive inflammation characterized by granulomatous enteritis resembling Crohn ' s disease and genitourinary obstruction . - pubmed
[ Continuous positive airway pressure treatment in sleep - related respiratory disorders in children ] . - pubmed
Continuous positive airway pressure ( CPAP ) is the first choice in the treatment of apnea - hypopnea syndrome in adults and , in recent years , is considered the second option after surgery in children . - pubmed
Oleanolic acid inhibits hypertrophic scarring in the rabbit ear model . - pubmed
METHODS : A rabbit ear model of hypertrophic scarring was used , with wounds produced with a biopsy punch . - pubmed
RESULTS : Treatment with different concentrations of oleanolic acid ( OA ) for 22 days significantly inhibited hypertrophic scarring in rabbit ear tissue . - pubmed
CONCLUSIONS : OA suppresses hypertrophic scarring in the rabbit ear model and may be an effective cure for human hypertrophic scarring . - pubmed
Data for the acute and chronic excess toxicity of anilines and other ' polar narcotics ' for D. - pubmed
CASE REPORT : An 87 - year - old woman presented with a four - month history of left - sided otorrhoea and otalgia . - pubmed
What is the best criterion for the interpretation of adrenal vein sample results in patients with primary hyperaldosteronism ? - pubmed
BACKGROUND : In patients with primary hyperaldosteronism , adrenal vein sampling ( AVS ) has emerged as a gold standard for distinguishing between unilateral and bilateral disease , but multiple criteria have been used and no consensus exists as to the most accurate criterion . - pubmed
METHODS : This is a retrospective analysis of AVS results in 108 patients with primary hyperaldosteronism treated at a single institution . - pubmed
pGFPshIGF-1R was delivered into A549 cells in vitro and injected intravenously into the tumor - bearing mice every 48 h for four doses in vivo by way of lipofection or magnetofection . - pubmed
At Week 3 after the 4th injection , the mice were sacrificed and the tumors removed and weighed . - pubmed
RS extends lifespan in obese rats . - pubmed
A 56 - year - old man had left nephrectomy and resection of a cavoatrial tumor thrombus under a cardiopulmonary bypass assist for left renal cell carcinoma . - pubmed
Our experience with endoscopic sphenopalatine artery ligation for four patients with posterior existaxis is described . - pubmed
All patients had epistaxis refractory to anterior and posterior nasal packing , which was rapidly controlled following the procedure . - pubmed
PURPOSE : Many dry eye ( DE ) patients are sensitive to adverse environments where tear evaporation rate ( TER ) increases . - pubmed
Influenza viruses are respiratory pathogens that continue to pose a significantly high risk of morbidity and mortality of humans worldwide . - pubmed
Patients sustaining PE and severe blebitis following trabeculectomy or a combined trabeculectomy with a cataract extraction procedure performed from 1990 through 2008 and diagnosed from 1990 through 2012 were recorded at St Erik Eye Hospital . - pubmed
DB844 ( CPD-594 - 12 ) , N - methoxy-6 -{ 5 -[ 4 -( N - methoxyamidino ) phenyl ]- furan-2 - yl }- nicotinamidine , is an oral prodrug that has shown promising efficacy in both mouse and monkey models of second stage human African trypanosomiasis . - pubmed
However , gastrointestinal ( GI ) toxicity was observed with high doses in a vervet monkey safety study . - pubmed
METHODS : In all , 16 hospitalized patients ( 27.1 + - 11.3 years ) with moderate / severe TBI wore actigraphs for 10 days , starting in the intensive care unit ( ICU ) when continuous sedation was discontinued and patients had reached medical stability . - pubmed
Predicting chemotherapy toxicity in older adults with lung cancer . - pubmed
OBJECTIVE : Existing oncology performance status measurements are used to predict chemotherapy toxicity in all patients with cancer , regardless of age . - pubmed
We investigated whether this tool can usefully characterize chemotherapy risks for older patients with lung cancer . - pubmed
METHODS : Patients from our hospital aged & gt;= 65 years with lung cancer completed a questionnaire form prior to chemotherapy . - pubmed
RESULTS : Between September 2011 and September 2012 , 120 patients with lung cancer ( 87 males and 33 females ) & gt;= 65 years of age ( mean : 69 years ; range : 65 - 82 years ) were enrolled in the study . - pubmed
CONCLUSION : This new CARG toxicity tool can be used to better distinguish the risks of chemotherapy toxicity than the KPS for older patients with lung cancer , and may change the standards for oncology assessments . - pubmed
Cardiac arrest due to left circumflex coronary artery embolism as a complication of subtherapeutic oral anticoagulation in a patient with mitral and aortic mechanical valve prostheses . - pubmed
We report a case of a 65 - year - old female patient after replacement of aortic and mitral valve with mechanical prostheses and implantation of a pacemaker hospitalized in our clinic due to acute coronary syndrome complicated with cardiac arrest due to ventricular fibrillation . - pubmed
In spite of their proven efficacy in the prevention of ischaemic stroke related to atrial fibrillation and prevention or treatment of deep vein thrombosis and pulmonary embolism , the use of new oral anticoagulants for the treatment of patients with mechanical valve prostheses needs further research . - pubmed
This exciting development , coupled with ongoing clinical trials of a range of other novel compounds , is bringing hope to patients and their clinicians and raises the prospect that , in the future , it may become possible to successfully arrest the development of progressive scarring in IPF . - pubmed
Treadmill exercise ameliorates symptoms of attention deficit / hyperactivity disorder through reducing Purkinje cell loss and astrocytic reaction in spontaneous hypertensive rats . - pubmed
We investigated the effects of treadmill exercise on Purkinje cell and astrocytic reaction in the cerebellum of the ADHD rat . - pubmed
Adult male spontaneously hypertensive rats ( SHR ) and Wistar - Kyoto rats ( WKYR ) weighing 210 + - 10 g were used . - pubmed
The animals were randomly divided into four groups ( n= 15 ): control group , ADHD group , ADHD and methylphenidate ( MPH)-treated group , ADHD and treadmill exercise group . - pubmed
We analysed the outcomes of management of 1,768 patients presenting with various forms of lower - limb phlebothrombosis . - pubmed
MATERIALS AND METHODOLOGY : We recruited 16 NOW women with PCOS ( NOW - PCOS ) and 10 normally ovulating NOW women ( control - NOW ) . - pubmed
[ Submucosal bacterial abscesses of the ascending colon and liver associated with portal and superior mesenteric vein thrombosis due to Enterococcus faecalis infection : a case report ] . - pubmed
A 72 - year - old woman with diabetes mellitus was admitted with fever and general fatigue . - pubmed
The abscesses were determined to be associated with Enterococcus faecalis infection . - pubmed
The prospective study , not randomized and controlled , referred to the insertion of 18 implants on 9 patients with mono or bilateral edentulism , with measurements at 1 , 3 , 6 and 12 months and an overall follow - up at 3 years , in order to evaluate the different degree of crestal bone resorption using the submerged and transmucosal surgical technique . - pubmed
Prevalence of ESBL - E was 77 6 % ( 45/58 ) in TBRI and 6 5 % ( 13/199 ) in Bj ( P & lt ; 10 - 7 ) . - pubmed
My Approach to the use of NOACs for stroke prevention in patients with atrial fibrillation . - pubmed
METHODS : 488 participants , including 192 glaucoma , 112 age - related macular degeneration , 91 diabetic retinopathy and 93 healthy volunteers , completed the Assessment of Disability Related to Vision ( ADREV ) mobility course . - pubmed
Case presentation - A five - year survival of the patient with glioblastoma brain tumor . - pubmed
This paper presents an atypical case of a patient with brain tumor of the glioblastoma multiforme ( GBM ) type who achieved a 5 - year survival . - pubmed
METHODS : Prospectively collected data of patients with true aneurysmal degeneration of the inflow artery after fistula creation ( excluding pseudoaneuryms , anastomotic or infected aneurysms , or surgical complications ) , surgically repaired between January 2010 and February 2014 ( cohort study ) have been included . - pubmed
RESULTS : 12 patients ( 75 % men , median age 63 years ) were treated for aneurysmal degeneration of the axillary ( 1 ) , brachial ( 6 ) , or radial ( 5 ) artery . - pubmed
Most patients were symptomatic ( pain [ 6 ] , distal embolization [ 1 ] ) . - pubmed
Patients had previous lesions that were Breast Imaging Reporting and Data System 4 and 5 based on mammography and/or ultrasonographic imaging . - pubmed
This prospective comparative case series included sixty eyes of 42 patients undergoing cataract surgery . - pubmed
In the present study , tebuconazole and myclobutanil enantiomers were isolated and used to evaluate the occurrence of enantioselectivity in their acute toxicity to three non - target organisms ( Scenedesmus obliquus , Daphnia magna , and Danio rerio ) . - pubmed
Sealing a ruptured non - culprit coronary plaque in a patient with acute myocardial infarction with bioresorbable vascular scaffolds . - pubmed
A 49 - year - old man was admitted to the emergency department suffering from a large anterior myocardial infarction that was treated by rescue PCI . - pubmed
METHODS AND RESULTS : Eighty patients with PAF were randomized in a 1:1 ratio to undergo either fluoroscopically guided pulmonary vein isolation ( PVI ) ( X+ ) or PVI without fluoroscopy ( X- ) . - pubmed
Acute effects of Finnish sauna and cold - water immersion on haemodynamic variables and autonomic nervous system activity in patients with heart failure . - pubmed
BACKGROUND : The haemodynamic response to Finnish sauna and subsequent cold - water immersion in heart failure patients is unknown . - pubmed
RESULTS : Cardiac output and heart rate significantly increased in all groups after sauna and cold - water immersion ( p & lt ; 0.05 ) , except for coronary artery disease patients after sauna exposure . - pubmed
No change in the low / high frequency ratio was found in chronic heart failure patients . - pubmed
In coronary artery disease patients and controls a prolonged increase in low frequency / high frequency ratio was observed after the first sauna exposure . - pubmed
CONCLUSIONS : Acute exposure to Finnish sauna and cold - water immersion causes haemodynamic alterations in chronic heart failure patients similarly to control subjects and in particular did not provoke an excessive increase in adrenergic activity or complex arrhythmias . - pubmed
Hormone replacement therapy and the risk of subarachnoid hemorrhage in postmenopausal women . - pubmed
The goal of this study was to determine the effect of HRT on occurrence of SAH in a large prospective cohort of postmenopausal women . - pubmed
An MFC inoculated with strain HJ and operated in open circuit produced 47 % and 57 % of the maximal power produced from MFCs inoculated with the known electrogen Geobacter daltonii and the magnetotactic bacterium Desulfamplus magnetomortis , respectively . - pubmed
Intracranial capillary hemangioma in an elderly patient . - pubmed
We report an extremely rare case of rapidly rising intracranial capillary hemangioma in an elderly woman . - pubmed
CASE DESCRIPTION : The 82 - year - old woman presented with vomiting , reduced level of consciousness , and worsening mental state . - pubmed
CONCLUSION : This is the first description of rapid growth of an intracranial capillary hemangioma in an elderly woman . - pubmed
All Salmonella strains were tested for their susceptibility to the antibiotics using disk diffusion method and screened for the presence of virulence genes and class I integrons using PCR . - pubmed
METHODS : This retrospective study involved 27 patients who presented with periocular mass ( final diagnosis of lipogranuloma ) and had history of facial autologous fat injection . - pubmed
Fifty - seven dogs with sinonasal tumors met inclusion criteria . - pubmed
The median overall survival times in dogs with tumor type of CA , SA , and OSA were 10.4 , 10.7 , and 3.1 months , respectively . - pubmed
Dogs with the tumor type of OSA had shorter overall survival time than that in dogs with tumor type of CA and SA . - pubmed
The prevalence of heart failure ( HF ) is still increasing worldwide , with enormous human , social , and economic costs , in spite of huge efforts in understanding pathogenetic mechanisms and in developing effective therapies that have transformed this syndrome into a chronic disease . - pubmed
METHODS : The clinical data of 78 patients diagnosed with CSP from January 2010 to December 2013 were reviewed . - pubmed
Patients with excessive vaginal hemorrhage underwent either emergency UAE treatment or laparotomy . - pubmed
Diagnoses were established in 22 of 32 patients : 16 connective tissue diseases ( CTDs ) , mainly Sjogren syndrome ( SS , 5/16 ) , rheumatoid arthritis ( RA , 4/16 ) , and systemic lupus erythematosus ( SLE , 3/16 ) , and 6 nonautoimmune conditions . - pubmed
MATERIAL AND METHODS : Data were collected for 519 eligible gynecological cancer survivors , treated with pelvic radiotherapy , with a median follow - up of 5.8 years , using a study - specific questionnaire and medical records . - pubmed
In phase 2 , which focuses on return to activity , the patient continues the stretches and runs to the point of feeling iliotibial band tightness , but not pain . - pubmed
However , steroid - insensitive patients with eosinophil - enriched inflammation have also been described . - pubmed
The mechanisms that underpin infection - induced , severe steroid - insensitive asthma can be elucidated by using mouse models of disease . - pubmed
OBJECTIVE : We sought to develop representative mouse models of severe , steroid - insensitive asthma and to use them to identify pathogenic mechanisms and investigate new treatment approaches . - pubmed
METHODS : Novel mouse models of Chlamydia , Haemophilus influenzae , influenza , and respiratory syncytial virus respiratory tract infections and ovalbumin - induced , severe , steroid - insensitive allergic airway disease ( SSIAAD ) in BALB / c mice were developed and interrogated . - pubmed
Teamwork enables high level of early mobilization in critically ill patients . - pubmed
Reported reasons for not mobilizing patients , thereby excluding or delaying such intervention , are diverse and comprise safety considerations for high - risk critically ill patients with multiple organ support systems . - pubmed
This study sought to demonstrate that early mobilization performed within the first 24 h of ICU admission proves to be feasible and well tolerated in the vast majority of critically ill patients . - pubmed
We will highlight the diagnostic uses of HSCA in children , as well as pitfalls encountered . - pubmed
Patients with non - cancerous chronic pain completed questionnaires , and investigators also completed questionnaires . - pubmed
CONCLUSIONS : The long - term administration of fentanyl matrix in patients with non - cancerous pain can reduce the intensity of pain and significantly improves activities of daily living and physical and mental capabilities . - pubmed
Calcium - independent disruption of microtubule dynamics by nanosecond pulsed electric fields in U87 human glioblastoma cells . - pubmed
Seizure - associated central apnea in a rat model : Evidence for resetting the respiratory rhythm and activation of the diving reflex . - pubmed
Respiratory derangements , including irregular , tachypnic breathing and central or obstructive apnea can be consequences of seizure activity in epilepsy patients and animal models . - pubmed
We sought to characterize seizure - associated central apneic episodes as an indicator of seizure impact on the respiratory rhythm in rats anesthetized with urethane and given parenteral kainic acid to induce recurring seizures . - pubmed
One hundred ninety central apnea episodes ( 1.04 to 36.18s , mean : 3.2 + -3.7s ) were recorded during seizure activity from 7 rats with multiple apneic episodes . - pubmed
Differences between the respiratory phase at the onset of apnea and the corresponding offset phase varied widely , even within individual animals . - pubmed
18F - AV-1451 PET Imaging in Three Patients with Probable Cerebral Amyloid Angiopathy . - pubmed
Three patients with probable CAA underwent 11C - Pittsburgh Compound B ( PiB ) PET or 18F - florbetaben PET to evaluate amyloid burden , and 18F - AV-1451 PET to evaluate paired helical filament tau burden . - pubmed
Yet , human studies are limited in their ability to elucidate the physiological mechanisms by which abnormal facet loading leads to pain . - pubmed
Culex flavivirus ( CxFV ) is an insect - specific flavivirus infecting Culex mosquitoes , which are important vectors of West Nile virus ( WNV ) . - pubmed
During both years , the CxFV infection status of mosquito pools was associated with environmental factors such as habitat type and precipitation frequency rather than coinfection with WNV . - pubmed
To explore the effects of PD pathology on brain connectivity , we characterized with an emergent computational approach the brain metabolic connectome using [ 18F ] FDG - PET in early idiopathic PD patients . - pubmed
These findings expand previous imaging evidence of altered connectivity in cognitively stable PD patients by showing pathology - based connectivity changes and disease - specific metabolic architecture reconfiguration at multiple scale levels , from the earliest PD phases . - pubmed
Baseline patient and procedural characteristics and ischemic involvement of the striatocapsular and distal MCA territory [ iSCI , as opposed to non - isolated SCI ( niSCI ) ] were analyzed using multivariate logistic regression models . - pubmed
RESULTS : iSCI was detected in 53 patients ( 25.7 % ) , and niSCI was detected in 153 patients ( 74.3 % ) . - pubmed
In successfully reperfused patients , TICI 3 was found to be an additional factor associated with iSCI ( aOR 5.282 , 1.759 - 15.859 ) . - pubmed
Patients with iSCI had higher rates of substantial neurological improvement ( 71.7 vs. 37.9 % , p & lt ; 0.001 ) and higher rates of good functional short- and mid - term outcome ( 58.3 vs. 23.7 % , p & lt ; 0.001 and 71.4 vs. 41.7 % , p & lt ; 0.001 ) . - pubmed
However , while iSCI patients , in general , had a more favorable outcome , considerable heterogeneity in outcome was observed . - pubmed
The high prevalence of iSCI in successfully reperfused patients with good collaterals corroborates previous concepts of iSCI pathogenesis . - pubmed
This may have implications for patient rehabilitation and pathophysiological analyses of ischemic damage confined to subcortical regions of the MCA territory . - pubmed
The complex interplay of climate change , human migration influences and socio - economic factors lead to changing patterns of respiratory infections in tropical climate but also increasingly in temperate countries . - pubmed
But , as human migration patterns evolve , we expect to see more TB cases in higher income as well as temperate countries , and rise in infections like scrub typhus from ecotourism activities . - pubmed
Mouse Models of Acinetobacter baumannii Infection . - pubmed
This unit describes basic protocols for infecting mice through intranasal and intraperitoneal routes with Acinetobacter baumannii to induce associated pneumonia and sepsis , the two most common manifestations of clinical infections with this pathogen . - pubmed
By selecting the appropriate protocols and bacterial strains of different virulence , these mouse models provide an opportunity to study the infection pathogenesis and host - immune responses , and to evaluate the efficacies of prophylactic and therapeutic anti - A. - pubmed
Despite great progress in diagnostic and therapeutic techniques over the last few decades , the prognosis for patients with LSCC remains poor . - pubmed
These findings elucidated a novel molecular mechanism for the pathogenic mechanism in LSCC carcinogenesis and progression , and may have a potential role in the treatment of patients with LSCC . - pubmed
The cytotoxic effects of dimethyl sulfoxide in mouse preimplantation embryos : a mechanistic study . - pubmed
Conclusion : These results provide a significant contribution to finding effective protective agents to combat DMSO mediated reproductive toxicity for application in human embryos in the near future . - pubmed
A retrospective review of 101 NF - PNET patients following curative resection and lymphadenectomy was conducted . - pubmed
These results indicate that preoperative NLR & gt;= 1.80 , tumor size & gt;=2.5 cm and symptomatic diagnosis are independently associated with LN metastases for patients undergoing resection of NF - PNETs . - pubmed
Inhaled nitrous oxide can reduce the pain perception in post Caldwell - Luc operation patients - a randomised trial . - pubmed
MATERIAL AND METHODS : Data were collected from all patients ( n=1103 ) with STEMI subjected to primary PCI in Tyumen cardiology center from 2006 to 2014 . - pubmed
CONCLUSION : Swept - source OCTA is a reproducible technique in the assessment of macular perfusion in diabetic patients with special regards to foveal avascular zone analysis . - pubmed
Oxygen - glucose deprivation was used as a model of cerebral ischemia and IPC in cultured rodent astrocytes and neurons . - pubmed
Levels of Soluble Endothelium Adhesion Molecules and Complications among Sickle Cell Disease Patients in Ghana . - pubmed
Generally , SCD patients with complications had relatively higher levels of the soluble proteins compared to those in the steady - state . - pubmed
This might reflect an ongoing endothelial dysfunction in these patients . - pubmed
SCD patients with vaso - occlusive crisis presents with a more severe pathophysiology condition . - pubmed
Corrigendum to ' Morphological Changes in Different Populations of Bladder Afferent Neurons Detected by Herpes Simplex Virus ( HSV ) Vectors with Cell - type - specific Promoters in Mice with Spinal Cord Injury ' [ Neuroscience 364 ( 2017 ) 190 - 201 ] . - pubmed
Background : Articular cartilage diseases are considered a major health problem , and tissue engineering using human mesenchymal stem cells ( MSCs ) have been shown as a promising solution for cartilage tissue repair . - pubmed
Conclusion : Hesperidin could serve as a therapeutic agent to effectively enhance chondrogenesis of human MSCs by inhibiting inflammation to facilitate cartilage tissue repair . - pubmed
The gelling time of glycol chitin / PAA is 16 minutes at 25 C and 3 minutes at 37 C , which is convenient for doctors to inject the in - situ gel formulations into the tumor location of patient . - pubmed
The antitumor activity ( IC50 ) obtained by Centarea sinaica ; 3.1 + - 6.9 microg / ml , 14.3 + - 3.1 microg / ml and 22.7 + - 4.1 microg / ml was better than activity of vinblastine sulphate ; 5.9 + - 0.4 microg / ml , 59.7 + - 2.1 microg / ml and 30.3 + - 1.4 microg / ml against breast carcinoma ( MCF-7 ) , cervical carcinoma ( Hela ) and colorectal carcinoma ( CACO ) , respectively . - pubmed
Plectranthus arabicus alcoholic extract showed higher antitumor activity ; 15.3 + - 5.3 microg / ml , 28.6 + - 3.6 microg / ml and 24.3 + - 4.1 microg / ml than vinblastine ; 21.2 + - 0.9 microg / ml , 59.7 + - 2.1 microg / ml and 30.3 + - 1.4 microg / ml against prostate carcinoma ( Pc3 ) , cervical carcinoma ( Hela ) and colorectal carcinoma ( CACO ) , respectively . - pubmed
Also , the antitumor activity of Plectranthus asirensis against cervical carcinoma ( Hela ) ( 37.1 + - 2.6 microg / ml ) was potent than vinblastine sulphate ( 59.7 + - 2.1 microg / ml ) . - pubmed
A subset of traumatic brain injury ( TBI ) patients exhibit cognitive deficits later in life which may be due to the underlying pathology associated with Alzheimer ' s disease ( AD ) or chronic traumatic encephalopathy . - pubmed
The beta2 - microglobulin amyloidosis is a newly recognized type of systemic amyloidosis , which occurs in patients with chronic renal failure undergoing long - term hemodialysis . - pubmed
Two patients were referred to the Oral Medicine Clinic due to the presence of multiple nodules on the tongue and macroglossia . - pubmed
The patients had history of chronic renal failure and had been dialysed for more 20 years with bio - incompatible cellulose membrane . - pubmed
Furthermore , in patients with oral amyloidosis , lesions in areas of trauma may ulcerate and cause pain and dysphagia becoming necessary periodic surgical removal and regular follow - up of these patients . - pubmed
Virulence genes and genetic diversity assessment of Shiga toxin - producing Escherichia coli O91 strains from cattle , beef and poultry products . - pubmed
A panel of 21 virulence genetic markers associated with human and animal infections was evaluated and the relatedness among strains was determined by a multiple - locus variable - number tandem repeats analysis ( MLVA ) comprising 9 VNTR loci . - pubmed
However , this technology will certainly improve our knowledge of the causes of human gut infections . - pubmed
METHODS : A retrospective study was conducted on 128 patients with Adolescent Idiopathic Scoliosis ( AIS ) , with baseline and follow - up radiograph and surface topography assessments . - pubmed
There was effect modification by human immunodeficiency virus ( HIV ) status , with HIV - positive patients having an aHR of 5.33 ( 95%CI 1.76 - 16.12 ) . - pubmed
Further investigation into the impact of HIV on the relation of DM to death is necessary . - pubmed
Wheat production is facing the stresses of different diseases including Fusarium head blight ( FHB ) which is more and more serious recently and leading to highly concerns . - pubmed
In this review , we summarize the current status of the research against FHB in wheat and discuss the issues of FHB resistance investigation to date . - pubmed
Moreover , hippocampus neuron apoptosis and cognitive impairment were significantly improved with the pretreatment of BAY 11 - 7082 in rats subjected to CIH . - pubmed
The study evaluated the effectiveness of ' Mass Vaccination Campaign ( MVC ) ' implemented against the contagious transboundary OIE notified Peste des petits ruminants ( PPR ) in sheep and goats on the lines of ' pulse polio campaign ' for humans in Chhattisgarh state , India . - pubmed
Effects of micronised microencapsulated ferric pyrophosphate supplementation in patients with advanced cancer and iron deficiency : a single - centre cohort pilot study . - pubmed
BACKGROUND : Iron deficiency is the most common nutritional deficiency in advanced cancer patients and causes anaemia . - pubmed
The aim of this study was to evaluate the efficacy of an oral administration of 30 mg of MMFP associated with 80 mg of ascorbic acid in advanced cancer patients with hyposideraemia . - pubmed
MATERIALS AND METHODS : This was an observational prospective cohort study ( 10 months ) conducted on 42 adult patients with advanced cancer and serum iron levels lower than 60 mug / dL. - pubmed
DISCUSSION : The supplementation of 30 mg / d of MMFP in combination with 80 mg / d of ascorbic acid in advanced cancer patients with hyposideraemia led to a significant increase in sideraemia and ferritinaemia . - pubmed
The observations on HPV - related OPSCC and its prognostic implications have coincided with increasing utilization of transoral surgical approaches to oropharyngeal tumors , such as transoral laser microsurgery ( TLM ) and transoral robotic surgery ( TORS ) . - pubmed
These approaches were once thought to only be applicable to patients with low T - stage OPSCC tumors ; however , they are being increasingly utilized in locally advanced OPSCC cases as several studies have shown that both of these transoral approaches are oncologically sound alternatives to concurrent chemoradiation therapy ( CCRT ) , which was previously the standard - of - choice treatment in patients with locally advanced disease . - pubmed
METHODS : CONVERT randomized patients with limited - stage SCLC to twice - daily ( 45 Gy in 30 fractions ) or once - daily ( 66 Gy in 33 fractions ) chemoradiotherapy . - pubmed
Apart from a higher incidence of late esophagitis in patients staged with conventional imaging ( for grade & gt;=1 , 19 % versus 11 % ; [ p = 0.012 ] ) , the incidence of acute and late radiotherapy - related toxicities was not different between the two groups . - pubmed
We investigated the impact of pre - hydration on tumour cisplatin concentrations in mice , and on treatment outcomes in a clinical cohort study . - pubmed
MATERIALS AND METHODS : Four groups of 20 mice received either no pre - hydration prior to full - dose ( 6 mg / kg ) or half - dose cisplatin , overnight dehydration prior to full - dose cisplatin ( dehydration ) , or NaCl intraperitoneally prior to full - dose cisplatin ( pre - hydration ) . - pubmed
In patients , a retrospective study compared 2 historical NSCLC cohorts which received CCRT with daily cisplatin , with and without standard pre - hydration . - pubmed
RESULTS : Pre - hydration significantly decreased cisplatin tumour concentrations in mice , comparable to mice receiving half the dose . - pubmed
CONCLUSION : Pre - hydration reduces cisplatin tumour concentrations in mice , but it does not compromise treatment outcomes in NSCLC patients treated with daily cisplatin and radiotherapy . - pubmed
Schima superba is traditionally used in China for heat clearing , detoxification , and treatment of furuncles . - pubmed
BACKGROUND : Clubroot disease caused by Plasmodiophora brassicae ( Phytomyxea , Rhizaria ) is one of the economically most important diseases of Brassica crops . - pubmed
Inter - arm Blood Pressure Difference is Associated with Recurrent Stroke in Non - cardioembolic Stroke Patients . - pubmed
Recurrent stroke increases mortality and aggravates the disability of stroke patients . - pubmed
We hypothesized that increased inter - arm systolic blood pressure difference and inter - arm diastolic blood pressure difference would be related to recurrent stroke in non - cardioembolic stroke patients . - pubmed
A total of 1226 consecutive non - cardioembolic first - ever ischemic stroke patients , in whom bilateral brachial blood pressures were measured by an automated ankle - brachial index measuring device , were included in our study . - pubmed
During a median 24 months of follow - up , 105 ( 8.5 % ) patients experienced recurrent stroke . - pubmed
Patients who had inter - arm systolic blood pressure difference & gt;=10 mmHg showed increased risk of recurrent stroke ( hazard ratio:1.77 , 95 % confidence interval : 1.04 - 3.00 , p = 0.033 ) . - pubmed
In conclusion , inter - arm blood pressure difference & gt;=10 mmHg may be associated with increased risk recurrent stroke in non - cardioembolic stroke patients . - pubmed
Results : In total , 60 CRE were detected in the 704 stool samples ( 8.5 % ) , including 42 Klebsiella pneumoniae , 7 Escherichia coli , 3 Citrobacter freundii , 3 Klebsiella oxytoca , 3 Enterobacter cloacae , 1 Enterobacter aerogenes , and 1 Raoultella planticola . - pubmed
SIGNIFICANCE : Fusarium head blight causes widespread damage to crops , and chronic and acute toxicity to human and livestock due to the accumulation of toxins during infection . - pubmed
To this end , we analyzed previously published whole - genome sequencing data for 384 tumor and progenitor tissues along with 423 publicly available normal tissue epigenomic features and single cell RNA - seq data from human livers to assess correlation patterns and extended this information to conduct in - silico prediction of the cell - of - origin for primary liver cancer subtypes . - pubmed
Defining spatial units that consider transmission heterogeneity , human movement and migration will help to set up achievable malaria elimination milestones and guide the creation of efficient operational administrative control units . - pubmed
When compared with the control group over 70 days , the minocycline and minocycline plus immunotherapy groups of rabbits with pythiosis showed significantly reduced injuries . - pubmed
Cochlear implantation in prelingually deaf children with white matter lesions . - pubmed
METHODS : The data of forty - five children with WMLs who received CI from 2011 to 2014 were retrospectively reviewed . - pubmed
CONCLUSIONS : The auditory and speech abilities of prelingually deaf children with WMLs and those without WMLs can improve after CI . - pubmed
OBJECTIVES : In Korea , there have been a few studies on Korean FPV and CPV-2 strains . - pubmed
RESULTS : The parvoviruses strains were newly classified into FPV , CPV 2 - I , CPV 2 - II , and CPV 2 - III genotypes . - pubmed
In the strains isolated in this study , Gigucheon , Rara and Jun belong to the FPV , while Rachi strain belong to CPV 2 - III . - pubmed
The root of CPV - I strains were inferred to be originated from a USA strain , while the CPV - II and III were derived from Italy strains that originated in the USA . - pubmed
Induction of Posterior Vitreous Detachment in Pediatric Patients by Radial Perifoveal Stripping . - pubmed
CASE : A 5 year old girl underwent 25- gauge pars plana vitrectomy for optic pit maculopathy . - pubmed
Tislelizumab in Chinese patients with advanced solid tumors : an open - label , non - comparative , phase 1/2 study . - pubmed
METHODS : The purpose of this phase 1/2 , open - label , non - comparative study was to examine the safety , tolerability , and antitumor activity of tislelizumab in adult ( > = 18 years ) Chinese patients with histologically or cytologically confirmed advanced solid tumors with measurable disease . - pubmed
Antitumor activity was observed in patients with multiple solid tumors . - pubmed
OBJECTIVE : To analyse factors associated with the development of early and late multiorgan failure ( MOF ) in trauma patients admitted to the intensive care unit ( ICU ) . - pubmed
We analysed the incidence , outcomes and the risk factors associated with early ( < 72 h ) or late ( beyond 72 h ) MOF in trauma ICU patients . - pubmed
RESULTS : After excluding patients with incomplete data , 9598 trauma ICU patients constituted the study population . - pubmed
CONCLUSIONS : Multiorgan failure was recorded in 10 % of trauma ICU patients , with early MOF being the predominant form . - pubmed
Interpreting auditory brainstem evoked responses and distortion product otoacoustic emissions in diabetic patients with normal hearing . - pubmed
We evaluated the auditory brainstem evoked responses ( ABRs ) and distortion product otoacoustic emission ( DPOAE ) results according to the presence of DM in subjects with normal hearing . - pubmed
45 ears in patients with type 2 diabetes mellitus and 85 ears in non - diabetic patients were finally enrolled in our study . - pubmed
Diabetic subjects also showed significantly lower amplitudes at f2 frequencies of 1001 , 1200 , 1587 , 4004 , 5042 , and 6348 Hz than non - diabetic subjects . - pubmed
Additionally , the prevalence of a DPOAE response , defined as 3 dB above the noise floor , was significantly lower in diabetic subjects than that in non - diabetic subjects . - pubmed
A 16S - rRNA phylogenetic analysis revealed that this strain was most closely related to Sphingomonas changbaiensis V2M44 T , Sphingomonas tabacisoli X1 - 8 T , and Sphingomonas flavalba ZLT-5 T with 97.1 , 97.0 , and 95.0 % 16S - rRNA sequence similarities , respectively . - pubmed
Patients with primarily mild TBI ( n = 39 ) completed rsfMRI scans at the sub - acute ( ~10 days ) and long - term ( ~18 months ) phases . - pubmed
Widespread increases in rsFC from the aMPFC and between the PCC and frontal regions were shown for younger patients at time of injury , but limited increases of rsFC were noted at ~18 months in older patients . - pubmed
CONCLUSION : Long - term increases in rsFC were found following TBI , but age at the time of injury was associated with distinct rsFC profiles suggesting that younger patients show greater increases in rsFC over time . - pubmed
METHODS : One hundred thirty - two patients with active RA and 72 healthy subjects were included in this study . - pubmed
We used the Vini in silico model of cancer to perform this virtual drug screening , showing HIV drugs to be the most effective . - pubmed
It is concluded that careful metabolic control of the pregnant diabetic patient results in a normal process of fetal pulmonary maturation without increased risk of RDS . - pubmed
It is concluded that anovulation with in situ luteinization may be a rather frequent cause of infertility in regularly cycling women . - pubmed
Two hundred forty - nine patients with squamous cell carcinoma seen and treated at Universtiy of Wisconsin Hospitals from 1960 - 1972 were analyzed as to recurrence rates , with emphasis on specific sites of recurrence , salvage rates , and end results . - pubmed
[ Determination of the metabolic clearance and production of estradiol in breast cancer patients at menopause ] . - pubmed
Intravaginal insertion of a 10 cm2 silastic device with an 0.5 % concentration of 15 ( S )- 15 - methyl - prostaglandin F2alpha methyl ester alone successfully induced abortion in 27 of 48 patients in the midtrimester and in an additional 11 patients with a concomitant infusion of oxytocin . - pubmed
In 8 of the 10 patients who failed to abort even with concomitant oxytocin therapy , abortion was induced by serial intramuscular injections of 15 - ME - PCF2alpha ; the remaining 2 failures underwent surgical evacuation . - pubmed
Vomiting and diarrhea were the most common side effects and in general well tolerated by the patients . - pubmed
However , there was an adverse reaction in a single patient who experienced almost constant nausea , vomiting and diarrhea . - pubmed
The production of secondary amines by the human gut bacteria and its possible relevance to carcinogenesis . - pubmed
40 PATIENTS WITH METASTATIC NEUROBLASTOMA HAVE BEEN Treated by a sequential multichemotherapy made of vincristine , adriamycin and cyclophosphamide . - pubmed
Nearly 2/3 of these streated tumors are drug - responders : 15 complete apparent remissions which are lasting in 11 patients since four to eighteen months ; and 13 good partial remissions . - pubmed
Genomic variation and segregation of equine infectious anemia virus during acute infection . - pubmed
We employed polymerase chain reaction to investigate the distribution and the level of genome variability of EIAV DNA in different tissues of a horse infected with a highly virulent variant of the Wyoming strain of the virus . - pubmed
The prospect of identifying and developing new agents for treatment of rhabdomyosarcomas is discussed in the light of current prognosis for children with advanced stage disease . - pubmed
The more complex system of identifying therapeutically active agents using human tumor xenografts has demonstrated usefulness . - pubmed
In six patients with pediatric malignancy and three newborns with suspected septicemia , CL induced by E. - pubmed
aeruginosa was measured after the administration of 150 mg / kg of intact preparations , and 4/6 of malignancy showed increased CL by E. - pubmed
Intimal proliferation in coronary arteries of normolipidaemic pigs with a fixed stenosis : the effects of fish oil . - pubmed
In order to investigate the effect of fish oil on intimal proliferation of coronary arteries with a fixed stenosis , piglets were fed a diet to which either 9 % ( w / w ) lard fat ( L , n = 8) or 4.5 % ( w / w ) lard fat and 4.5 % ( w / w ) mackerel oil ( ML , n = 8) was added for 4 months . - pubmed
The stenosis was applied by implanting a Teflon constrictor around the left anterior descending coronary artery ( LADCA ) after the animals had been on their diet for two months . - pubmed
Using a special in vitro assay , we tested whether retinal ganglion cell axons in an adult vertebrate , the goldfish ( which can regenerate a retinotopic projection after optic nerve section ) , recognize position - specific differences in cell surface membranes of their target , the tectum opticum . - pubmed
[ The use of the gene responsible for formation of hemorrhage as a phenotypic marker in creating hybrid variations of vaccinia virus ] . - pubmed
No low dose threshold was observed in male Sprague - Dawley rats at different single doses of diethylnitrosamine ( DEN ) although a plateau was reached between 160 and 200 mg / kg body weight . - pubmed
Acute adrenal insufficiency in a patient with appendicitis during anesthesia . - pubmed
vulnificus wound infections and from gastroenteritis caused by vibrios other than V. - pubmed
Underlying hepatic or neoplastic disease ( especially leukemia ) apparently increases the likelihood and severity of illnesses caused by V. - pubmed
Subchronic exposure to styrene has been reported to produce high - frequency hearing loss in rats . - pubmed
In humans , hearing thresholds for higher frequencies ( greater than 8 kHz ) are also more vulnerable to ototoxic drugs than those at lower frequencies . - pubmed
Since hearing loss at frequencies above 8 kHz does not seem to play a role in speech processing , hearing loss at frequencies above 8 kHz in workers exposed to styrene or other solvents might easily escape detection . - pubmed
We evaluated 21 patients with chorioamnionitis in labor at term and used 21 matched control subjects . - pubmed
Use of thiazides in diabetic patients . - pubmed
Genetic analysis of an inherited deficiency of the third component of complement in Brittany spaniel dogs . - pubmed
Genetically determined C3 deficiency in Brittany spaniel dogs shares a number of biochemical and clinical characteristics with the human disorder . - pubmed
The current study used allotype analysis of canine C3 in order to demonstrate that the gene for C3 deficiency in these dogs is also a null gene allelic to the structural gene for C3 . - pubmed
In addition , preliminary pedigree analysis suggests that the gene for canine C3 deficiency is apparently not closely linked to the major histocompatibility complex of the dog . - pubmed
Thus , it appears that C3 deficiency in Brittany spaniel dogs not only shares biochemical and clinical features with C3 deficiency in humans , but also shares some genetic characteristics with the human disorder . - pubmed
Dose mortality studies on strain ' A ' mice exposed to 60Co gamma irradiation . - pubmed
Hemodynamic and blood - gas effects of Innovar in patients with acquired heart disease . - pubmed
Electron microscopic studies on the adrenal medulla and adrenal cortex of hypertensive rats . - pubmed
Spontaneously hypertensive rats . - pubmed
Electromyographic investigation of human vocal cord paralysis . - pubmed
A strain of Penicillium palitans , implicated in the deaths of dairy cows , produces an intracellular tremorgenic mycotoxin . - pubmed
Glucose-6 - phosphate dehydrogenase deficiency protects human fibroblasts against the benzo ( a ) pyrene - induced in vitro transformation . - pubmed
Isolation of human surfactant from amniotic fluid and a pilot study of its efficacy in respiratory distress syndrome . - pubmed
The organization of intermediate filaments in normal human colonic epithelium and colonic carcinoma cells . - pubmed
The presence of 12 viral ( herpes 1 and 2 , influenza A ( H1N1 ) , A ( H3N2 ) and B , parainfluenza 1 , 2 , 3 , adenovirus 5 ) and inframicrobial ( Chlamydia , mycoplasma , Rickettsia burneti ) antigens was investigated by direct or indirect immunofluorescence ( IF ) reactions in exfoliated conjunctival cells from 110 patients with nonbacterial keratitis and keratoconjunctivitis . - pubmed
Pyelon enlargement ( PPI decline ) in pathologically affected pregnant patients differed from that in clinically intact patients in the third trimenon only in cases of acute pyelonephritis ( 22 patients ) . - pubmed
Strain specific transplantable medullar carcinoma in DBA/2W mice . - pubmed
A solid medullar carcinoma , which arose spontaneously in DBA/2W mouse was passed in vivo in syngeneic and semisyngeneic recipients for ten generations without alteration of its morphology . - pubmed
Intra - abdominal hemorrhage in patients with hemophilia is uncommon but represents a major cause of death in hemophiliacs . - pubmed
Nineteen cases of intracranial ependymal tumors were reviewed to examine the prognostic factors influencing survival of the patients with this disease . - pubmed
These were patients presenting with asymmetrical neurogenic atrophy involving one or more limbs who had no evidence of pyramidal tract dysfunction after 3 or more years of symptoms . - pubmed
METHODS : We reviewed our results in 165 patients with intrahepatic stones treated by percutaneous trans - hepatic cholangioscopy and lithotripsy in the past 12 years . - pubmed
CONCLUSIONS : Percutaneous trans - hepatic cholangioscopy and lithotripsy are good alternatives in treating primary intrahepatic stones , especially for those patients unsuitable for surgery . - pubmed
Poor renal uptake of Tc-99 m DMSA and Tc-99 m MDP in a patient with Fanconi syndrome and near normal glomerular filtration rate . - pubmed
The authors present a patient with Fanconi syndrome who demonstrated poor renal uptake of Tc-99 m DMSA and high urinary concentration of the tracer . - pubmed
Biopsy samples obtained by endoscopy to diagnose infection by H. - pubmed
331 patients with the following endoscopic diagnosis were studied : normal appearance ( n = 55 ) , gastritis ( 87 ) , gastric ulcer ( 49 ) , duodenal ulcer ( 120 ) , and duodenitis ( 20 ) . - pubmed
Patients with duodenal ulcer or duodenitis had the highest H. - pubmed
This is indicated by some these s as well as by the discovery of the contagious characteristics of pityriasis versicolor by Carl Ferdinand Eichstedt ( 1816 - 1892 ) who found a fungus as the cause ( 1846 ) , which was named Microsporon furfur later ( C. Robin 1853 ) . - pubmed
The participant was a 37 - year - old healthy woman ( mean cycle length = 26.7 days , SD + /- 1.8 ) with prospectively screened well - defined premenstrual syndrome ( PMS ) , not on hormones or other drugs , and without a psychiatric history . - pubmed
PURPOSE : This trial evaluated the toxicity and efficacy of high - dose carboplatin , etoposide , and ifosfamide followed by autologous stem - cell transplantation in patients with refractory or relapsed germ cell cancer . - pubmed
PATIENTS AND METHODS : Between August 1989 and September 1992 , 74 patients with refractory or recurrent germ - cell tumors received one cycle of escalating doses of carboplatin ( 1,500 to 2,000 mg / m2 ) , etoposide ( 1,200 to 2,400 mg / m2 ) , and ifosfamide ( 0 to 10 g / m2 ) . - pubmed
Seventy - four patients were assessable for toxicity and 68 for response . - pubmed
At this dosage , we treated 20 patients and observed World Health Organization ( WHO ) grade 3 and 4 hematotoxicity ( 100 % ) , nausea ( 100 % ) , diarrhea ( 30 % ) , and hepatotoxicity ( 10 % ) . - pubmed
All patients developed granulocytopenic fever . - pubmed
Patients with disease refractory to conventional - dose pretreatment had a poor prognosis , with only one of 23 patients surviving event - free at 7 months after high - dose chemotherapy ( HDT ) . - pubmed
BACKGROUND : Contrary to expectation , most studies have demonstrated that initiation of an angiotensin - converting enzyme ( ACE ) inhibitor in conventional doses in patients with heart failure reduces the diuretic efficacy of furosemide . - pubmed
METHODS AND RESULTS : Eight patients with heart failure treated with diuretics and ACE inhibitors for at least 3 months were studied . - pubmed
Cattle were evaluated on the number of treatment days required until the animals could be returned to the feedlot , and the death loss of cattle in the hospital pens . - pubmed
Microinjections of L - AP-3 ( 30 nmol / rat ) induced a hypotension similar to the one obtained with t - ACPD at the dose of 6 nmol / rat . - pubmed
Patients with malignant meningitis presenting with neuropsychiatric manifestations . - pubmed
Clinical suspicion of malignant meningitis is prompted by neurologic symptoms and signs in patients at risk for this oncologic complication . - pubmed
METHODS : Three patients with cancer with no neurologic symptoms were examined for malignant meningitis based on neuropsychiatric symptoms . - pubmed
RESULTS : The clinical presentation of malignant meningitis for three patients was neuropsychiatric . - pubmed
None of the patients had delirium during their initial presentation . - pubmed
CONCLUSIONS : It is important that clinicians recognize that psychiatric symptoms without neurologic findings may indicate malignant meningitis and that malignant meningitis needs to be included in the differential diagnosis of neuropsychiatric disorders in patients with cancer . - pubmed
Antiatherogenic effects of adjuvant antiestrogens : a randomized trial comparing the effects of tamoxifen and toremifene on plasma lipid levels in postmenopausal women with node - positive breast cancer . - pubmed
PATIENTS AND METHODS : Forty - nine postmenopausal patients with node - positive breast cancer were randomized in a trial that compared the effects of tamoxifen and toremifene on serum lipoproteins . - pubmed
Eleven clones of dengue virus 2 Mexican strain were selected by the size of their lytic plaques . - pubmed
Tumor - specific CTLs have been generated from peripheral blood mononuclear cells ( PBMC ) of healthy donors or patients with malignant tumors by in vitro stimulation with peptide epitopes derived from tumor - rejection antigens . - pubmed
Based on these findings , clinical vaccine trials using these antigenic peptides have recently begun in patients with melanoma as well as other tumors that express these antigens , and some tumor responses have been seen in a limited number of patients . - pubmed
Congenital and early - onset bilateral hearing impairment in children : the delay in detection . - pubmed
A retrospective review of 168 consecutive children with congenital or early - onset bilateral hearing impairment ( & gt ; 25 dB , 0.5 - 4 kHz , in the better hearing ear ) was conducted . - pubmed
BACKGROUND : Several ecologic analyses have shown significant positive associations between mean indoor radon concentrations and risk of leukemia at all ages ( acute myeloid leukemia and chronic lymphocytic leukemia ) and for children ( all leukemia , acute myeloid leukemia , and acute lymphoblastic leukemia [ ALL ] ) . - pubmed
Analysis of recovery time indexes in 5 - fluorouracil - treated cancer patients . - pubmed
Based on our previous experience in doxorubicin - treated patients , in whom we observed a significant increase of ventricular recovery time indexes , we analyzed these non- invasive parameters of myocardium electrical instability in forty - three 5 - fluorouracil - treated patients , to test the hypothesis of a mechanoelectrical disarrangement occurring in 5 - fluorouracil ( 5FU ) cardiotoxicity . - pubmed
In two of these patients , each of whom experienced an episode of peritonitis due to S. - pubmed
Nucleoside - nucleotide mixture increases bone marrow cell number and small intestinal RNA content in protein - deficient mice after an acute bacterial infection . - pubmed
The aim of this study was to determine if intraperitoneal administration of a nucleoside - nucleotide mixture would affect small intestinal morphology , bone marrow cell number , and DNA content in protein - deficient mice subjected to acute bacterial infection . - pubmed
Mice were randomized into two groups and orally fed protein - free diet or nucleotide - free 20 % casein diet for 10 d. The mice in each group were divided into two subgroups and intraperitoneally administered 0.35 mL saline or nucleoside - nucleotide mixture ( 17.5 mL / kg body weight ) for 10 d. On day 10 , one subgroup from each major dietary group was either inoculated intravenously with methicillin - resistant Staphylococcus aureus or saline . - pubmed
The pharmacokinetics of single 50 mg oral and intravenous doses of milnacipran , a new non tricyclic antidepressant drug , were compared in 11 chronic liver impaired ( LI ) subjects and in 6 control subjects . - pubmed
As the unchanged drug is the only compound responsible for the activity of milnacipran , no dosage adjustment is needed in patients presenting liver impairment . - pubmed
The use of ICD 's for the treatment of patients with Arrhythmogenic Right Ventricular Dysplasia ( ARVD ) - pubmed
Effect of adjuvant tamoxifen therapy on thyroid function in postmenopausal women with breast cancer . - pubmed
Behavioral disorders did not allowed the use of continuous positive pressure in this patient . - pubmed
Differences in the features of osteochondritis dissecans ( OCD ) affecting the lateral and medial femoral condyles were investigated in 13 patients ( 14 knees ) treated from 1991 to 1994 . - pubmed
Immunopathogenesis of human gastrointestinal infection by Anisakis simplex . - pubmed
BACKGROUND : Anisakis simplex is a parasite of fish , and in the case of human infestation , it should be considered as a possible cause of gastrointestinal disease , especially in countries where raw or undercooked fish is a frequent food . - pubmed
All patients underwent biopsy after emergency surgery caused by episodes of acute abdominal pain . - pubmed
OBJECTIVE : To determine the kinematics and kinetics of performing a weight - relief maneuver in persons with C5 and C6 quadriplegia . - pubmed
SUBJECTS : Seven persons with C5 and C6 quadriplegia ( ASIA A and B ) with " flickers " ( grade 1/5 ) or less in wrist flexor and triceps brachii muscles . - pubmed
The patient was a 74 - year - old woman who had undergone radical nephrectomy on the left side for renal cell carcinoma on April 23 , 1990 , and had been observed as an outpatient . - pubmed
Behavior of ambulatory blood pressure surrounding episodes of headache in mildly hypertensive patients . - pubmed
METHODS : We evaluated 76 patients with mild hypertension who underwent clinical evaluation , ambulatory BP monitoring , and questioning about the occurrence of headache and its characteristics during monitoring . - pubmed
The 24 - hour BP curves of patients with and without headache during monitoring were compared using analysis of variance for multiple factors and repeated measurements . - pubmed
Hourly averages of BP surrounding the episode and 24 - hour mean BP of patients with headache were compared using paired sample t tests . - pubmed
RESULTS : Twenty - five participants ( 33 % ) experienced headache during monitoring . - pubmed
120 patients with different types of diabetes mellitus were divided into groups by the presence and intensity of accompanying alcoholic intoxication : group 1 - -no alcohol intake ; group 2 - -rare alcohol intake ; group 3 - -moderate alcohol intake ; group 4 - -alcoholic abuse . - pubmed
Testing the ability of children with attention deficit hyperactivity disorder to accurately report the effects of medication on their behavior . - pubmed
Children with attention deficit hyperactivity disorder ( ADHD ) are often treated with central nervous system stimulants , making the evaluation of medication effects an important topic for applied behavior analysts . - pubmed
Double - blind placebo - controlled procedures were used to examine whether 6 children with ADHD could recognize the effects of their medication . - pubmed
Furthermore , the DNA haplotype associated with disease is useful in excluding individuals with phenotypically similar retinal conditions . - pubmed
CLINICAL RELEVANCE : The disease - associated haplotype allows for more accurate genetic counseling to be given to individuals with a Stargardt - like phenotype inherited in an autosomal dominant pattern . - pubmed
OBJECTIVE : To evaluate the efficacy of intraoperative ultrasound in obtaining adequate surgical margins in women undergoing lumpectomy for palpable breast cancer . - pubmed
SUMMARY BACKGROUND DATA : Adequacy of surgical margins is a subject of debate in the literature for women undergoing breast - conserving therapy . - pubmed
METHODS : Two groups of women undergoing lumpectomy for palpable breast cancer were studied , one group using intraoperative ultrasound ( n = 27 ) and the other without ( n = 24 ) . - pubmed
CONCLUSIONS : The use of ultrasound - guided surgery optimizes the surgeon 's ability to obtain satisfactory margins for breast - conserving techniques in patients with breast cancer . - pubmed
To examine the hypothesis that Pavlovian autoshaping provides an animal learning model of drug abuse , two studies evaluated the induction of ethanol drinking by autoshaping procedures . - pubmed
Similarly , Th1 vaccines would be useful in redirecting inappropriate antigen - specific immune responses in patients with autoimmune diseases and allergies . - pubmed
and peroral Encephalitozoon cuniculi infections was compared in adoptive - transfer experiments using severe combined immunodeficient mice . - pubmed
In addition , if the glomerular filtration rate reserve is compromised , all patients ( including those taking short term therapy ) should be closely monitored for the early detection of signs and symptoms of renal failure . - pubmed
OBJECTIVE : Radiosurgery - associated second tumors have been reported in four isolated patients during the past 2 years . - pubmed
METHODS : A review of the English - language literature concerning patients with radiosurgery - associated second tumors was performed . - pubmed
Of interest , three of the six patients experienced complications of the radiosurgery treatment before developing second tumors . - pubmed
CONCLUSION : Although patients will increasingly be reported with second tumors after radiosurgery in the future , the overall incidence seems quite low and should not alter current radiosurgical practice . - pubmed
[ Hyperostosis frontalis interna in a 30 year old man with hypophyseal - diencephalic dysregulation ] . - pubmed
[ The biology of Opisthorchis felineus and the spread of opisthorchiasis in the Rostov District ; preliminary communication ] . - pubmed
Acute myocardial infarction in man treated with cortisone . - pubmed
Streptococcus mutans belongs to the viridans group of oral streptococci , which is the leading cause of endocarditis in humans . - pubmed
The study involved 150 children with ALL . - pubmed
While it has been shown that the matrix ( M ) protein of the vesicular stomatitis virus ( VSV ) inhibits nuclear export of host cell mRNAs , the underlying mechanism has not been fully established . - pubmed
In each of nine rabbits idiotypic specificities present in the earliest bleedings were completely replaced after a few months ; subsequent changes occurred much more slowly . - pubmed
This compound was less potent than permethrin against ectoparasiticide - susceptible larvae of the lone star tick , Amblyomma americanum ( L. ) ( Acari : Ixodidae ) ; larvae of the southern cattle tick , Boophilus microplus ( Canestrini ) ; and adult stable fly , Stomoxys calcitrans ( L. ) ( Diptera : Muscidae ) in vitro , but it was significantly more potent than permethrin against the Santa Luiza strain of B. - pubmed
Most patients diagnosed with a meningioma undergo surgical resection to relieve neurological symptoms . - pubmed
Advocates of stereotactic radiotherapy have suggested this therapy in lieu of surgery particularly in poor surgical risk patients , patients with meningiomas in eloquent or surgically inaccessible locations and in patients of advanced age . - pubmed
Notwithstanding limited data , hydroxyurea has been modestly successful in patients with recurrent meningiomas . - pubmed
PATIENTS AND METHODS : Two hundred and sixty - seven consecutive patients , with newly diagnosed pure seminoma of the testis , were treated with adjuvant RT between 1992 and 2000 . - pubmed
After a median follow - up of 6.1 years ( range , 3.0 to 11.2 years ) , 11 out of 267 ( 4.1 % ) patients had developed lymph node recurrence , resulting in an actuarial 5 - year relapse - free survival of 96 % . - pubmed
PURPOSE OF REVIEW : Three cancers in people with HIV denote an AIDS diagnosis : Kaposi ' s sarcoma , high - grade B - cell non - Hodgkin ' s lymphoma and invasive cervical cancer . - pubmed
Endogenous mechanisms underlying the remodeling of neuronal circuitry after mammalian CNS injury or disease remain primarily unknown . - pubmed
METHODS AND RESULTS : At our center , from May 2000 to December 2003 , 165 patients ( mean age 64+/-10 , median 65 years ; 127 men , 38 women ) with symptomatic in - stent restenosis underwent either intracoronary brachytherapy or sham procedure . - pubmed
In 82 patients , intracoronary radiotherapy was carried out without complications , but one of the 83 patients who underwent sham procedure suffered small myocardial infarction . - pubmed
During follow - up , stent thrombosis with subsequent non - Q - wave myocardial infarction occurred in one patient in each group ( 6 days and 8 months after the procedure , respectively ) . - pubmed
At 6 months after the index procedure , repeat angiography was performed in 156 of the 164 patients with successful procedure ( rate 95 % ): restenosis ( stenosis & gt;50 % in diameter ) or reocclusion was observed in only 19 of 78 (= 24 % ) patients of the radiation but in 31 of 78 (= 40 % ) patients of the sham procedure group ( P=0.04 ) . - pubmed
Event - free survival ( free of death , myocardial infarction , target vessel revascularization ) at 1 year was 87 % for patients being radiated and 74 % for patients having undergone sham procedure ( P=0.05 ) . - pubmed
Suppressive effect of hyaluronan on chondrocyte apoptosis in experimentally induced acute osteoarthritis in dogs . - pubmed
Inflammatory pain was induced by the peripheral injection of formalin or carrageenan in awake mice . - pubmed
Eleven patients underwent reoperation because of problems related to the auto and/or homograft , progression of rheumatic mitral valve disease , and iatrogenic coronary insufficiency . - pubmed
We consider this procedure the best option for the surgical treatment of aortic valve disease in children and young adults . - pubmed
Cancer stem - like cells in human prostate carcinoma cells DU145 : the seeds of the cell line ? - pubmed
The analyses were based on the results of a standardized radiographic examination of 167 SGC horses with a mean age of 14 months . - pubmed
An ectopic ( intrapericardial ) lobe of the liver in a cat . - pubmed
Ligustrazine is an alkaloid isolated from the rhizome of Chuanxiong ( Ligusticum chuanxiong Hort ) , which is known to possess antioxidant , anti - inflammatory , anti - fibrosis and immunomodulative effects . - pubmed
MATERIALS AND METHODS : After institutional review board approval and informed consent , 25 men and 22 women ( mean age , 65.8 years ) with colorectal adenocarcinoma underwent 65 - second CT perfusion study . - pubmed
This information will be useful in studies of rice aneuploidy and cytogenetics . - pubmed
METHODS : Location and degree of stenosis of involved arteries were examined by the digital subtraction angiography in 52 patients with carotid TIA . - pubmed
Severe stenosis and occlusion occurred more frequently in TIA patients with short duration ( less than 1 hour ) and multiple attacks ( more than twice ) . - pubmed
CONCLUSION : Most patients with TIA of carotid systems have stenosis in intracranial or extracranial arteries . - pubmed
The role of an integrated back stability program in patients with chronic low back pain . - pubmed
Patient satisfaction was assessed by questionnaire , 89 % of patients considering their level of pain and functional impairment acceptable following the programme . - pubmed
A 30 - year - old woman presented with cervical lymphadenopathy and multiple non - tender , non - itching , erythematous papules over the neck , chest , and abdomen . - pubmed
The earlier detection of erosion may facilitate the timely initiation of disease - modifying antirheumatic drug therapy , particularly in patients with undifferentiated synovitis . - pubmed
METHODS : Patients presenting with synovitis for the first time were invited to participate . - pubmed
Seventeen patients ( 57 % ) had RA , and 13 ( 43 % ) had undifferentiated arthritis ( UA ) . - pubmed
Ten patients ( 33 % ) had US evidence of synovitis associated with a positive power Doppler ( PD ) signal ( P = 0.04 ) . - pubmed
Norfloxacin modulates the inflammatory response and directly affects neutrophils in patients with decompensated cirrhosis . - pubmed
METHODS : Thirty - one patients with cirrhosis receiving norfloxacin ( 400 mg / day ) were included . - pubmed
CONCLUSIONS : Norfloxacin but not trimethoprim / sulfamethoxazole modulates inflammatory response and directly affects neutrophils in patients with cirrhosis . - pubmed
Transplantation of human endothelial progenitor cells ( hEPCs ) may improve vascularization and left ventricular function after myocardial infarction . - pubmed
To this end , ( 111 ) In - oxinate - labeled hEPCs were infused by a minimally invasive technique into the coronary arteries of immunosuppressed Wistar rats under control conditions and after ischemia / reperfusion . - pubmed
We present the case of a 75 - year - old woman who suddenly developed hemiplegia , aphasia , and reduced consciousness three hours after embolization of a cerebral aneurysm . - pubmed
Our studies confirm the previously held belief that HIV-1 strains may harbor enhanced biological fitness upon recombination . - pubmed
Preliminary results of tranilast treatment for patients with advanced castration - resistant prostate cancer . - pubmed
This study examined whether tranilast has clinical benefit for prostate cancer patients . - pubmed
PATIENTS AND METHODS : Twenty - one Japanese patients with advanced castration - resistant prostate cancer ( CRPC ) were administered tranilast orally . - pubmed
CONCLUSION : Although this study involved only pilot data , it indicates that tranilast may improve the prognosis of patients with advanced CRPC . - pubmed
[ Climatic risk zoning for banana and litchi 's chilling injury in South China ] . - pubmed
Based on the 1951 - 2006 climatic observation data from 224 meteorological stations in South China ( Guangdong Province , Guangxi Autonomous Region , and Fujian Province ) and the historical information about the chilling injury losses of banana and litchi , the accumulated harmful chilling for the processes with minimum daily temperature & lt ; or = 5.0 degrees C and more than 3 days was used to indicate the climatic risk of chilling injury during the whole growth season , and an integrated climatic index with the background of climate change was constructed . - pubmed
The maps of geographical distribution of climatic risk probability for each grade chilling injury , and of integrated climatic risk zoning for banana and litchi 's chilling injury were drawn , and the spatial variation of climatic risk for banana and litchi 's chilling injury was commented . - pubmed
The geographical distribution of climatic risk probability for banana and litchi 's chilling injury showed a zonal pattern . - pubmed
According to the integrated climatic risk index , the banana and litchi 's chilling injury region was divided into three risk types , i.e. - pubmed
OBJECTIVE : To assess the cost utility of rasagiline or entacapone as adjunctive therapies to levodopa versus levodopa / carbidopa / entacapone ( LCE ) versus standard levodopa monotherapy in patients with advanced PD and motor fluctuations in the US . - pubmed
With no additional cost over a 2 - year period , rasagiline+levodopa presents a valuable alternative to entacapone+levodopa , LCE and levodopa monotherapy in the treatment of advanced PD patients . - pubmed
Results from this cost - utility model and prior adjunctive clinical data provide ongoing support for the adjunctive use of rasagiline in advanced PD patients with motor fluctuations . - pubmed
Patient centered outcomes in prostate cancer treatment : predictors of satisfaction up to 2 years after open radical retropubic prostatectomy . - pubmed
OBJECTIVE : The goal of the present study was to examine the prevalence of behavioural and emotional problems among children with high - functioning autism spectrum disorders ( ASD ) . - pubmed
METHOD : Archival data from a total of 71 children ( Mage = 10.24 , SD = 2.91 ) diagnosed by their clinicians to have high - functioning ASD were obtained . - pubmed
We describe the range of radial shortening that occurs following a fracture of the proximal radius , as well as the short - term outcome in these patients . - pubmed
PATIENTS AND METHODS : Over an 18 - month period , we prospectively assessed all patients with a radiographically confirmed proximal radial fracture . - pubmed
Patients noted to have ipsilateral wrist pain at initial presentation underwent bilateral radiography to determine whether there was disruption of the distal radio - ulnar joint suggestive of an Essex - Lopresti lesion . - pubmed
One patient with a Mason type - I fracture was lost to follow - up after initial presentation . - pubmed
RESULTS : 60 patients had ipsilateral wrist pain at the initial assessment of 237 proximal radial fractures . - pubmed
We divided the group of 540 cases with EV into another 2 subgroups : without variceal hemorrhage ( 375 patients ) and patients with a history of variceal bleeding ( 165 cases ) . - pubmed
The mean LS values in the group with a history of variceal bleeding ( 165 patients ) was statistically significantly higher than in the group with no bleeding history ( 375 patients ): 51.92 + - 1.56 kPa vs 35.20 + - 0.91 kPa , P & lt ; 0.0001 ) . - pubmed
There appeared to be a substantial number of late deaths , which may represent a combination of poor patient selection and treatment failures . - pubmed
Systemic therapy , with either cytotoxic chemotherapy and/or targeted therapies , has been established to provide benefit to patients with NSCLC in both the adjuvant and advanced disease settings . - pubmed
To investigate quantitatively and objectively the effects of repeated muscle vibration ( rMV ) of triceps surae on the gait pattern in a 5 - year - old patient with Cerebral Palsy with equinus foot deformity due to calf spasticity . - pubmed
The rMV technique seems to be an effective option for the gait pattern improvement in CP , which can be used also in very young patient . - pubmed
HISTORY AND ADMISSION FINDINGS : In the 20 - year - old patient increasing arthralgia since the age of seven years had caused functional impairment . - pubmed
Re : Low testosterone concentrations and the symptoms of testosterone deficiency according to the Androgen Deficiency in Ageing Males ( ADAM ) and Ageing Males ' Symptoms Rating Scale ( AMS ) questionnaires . - pubmed
Results are presented for two four - contact nerve - cuff electrodes stimulating bilateral femoral nerves of one human subject with spinal cord injury . - pubmed
The aim of this case report is to point to the possibility of CSS in patients presenting with extensive skin lesions masquerading as Stevens - Johnson Syndrome / Toxic Epidermal Necrolysis Syndrome ( SJS / TENS ) . - pubmed
All subjects provided spot urine samples , and 125 smokers provided blood samples . - pubmed
Formation of micronuclei and other nuclear anomalies in exfoliated nasal and oral cells : results of a human study with workers in a power plant processing poultry litter . - pubmed
Nuclear anomalies which reflect genotoxic and cytotoxic effects were monitored in exfoliated buccal and nasal cells which were collected from workers ( n = 25 ) of a power plant which processes chicken manure and from controls ( n = 21 ) . - pubmed
Taken together , the results show that anomalies that are due to cytotoxicity are increased in the workers and suggest that the exposure may lead to inflammations in the respiratory tract . - pubmed
Accuracy of MRI in the diagnosis of meniscal tears in older patients . - pubmed
OBJECTIVE : The objective of our study was to determine the accuracy of MRI in diagnosing meniscal tears in older patients and the frequency with which abnormal MRI findings correlate with degeneration , fraying , and tears at arthroscopy . - pubmed
CONCLUSION : The accuracy of MRI for diagnosing meniscal tears in older patients is high and similar to that in younger patients when only definitive findings are considered a tear . - pubmed
To this aim , we have used the optically transparent zebrafish larval brain and identified rapidly propagating Ca2 + waves that determine the range of microglial responses to neuronal cell death . - pubmed
Feline immunodeficiency virus ( FIV ) infection of cats provides a valuable model to study NK cell function in vivo . - pubmed
Among them , compound 22 d showed antiproliferative effects toward several human lung cancer cell lines ( A549 , H1299 , and CL1 - 5 ) ; it exhibited cytotoxicity against human lung CL1 - 5 cells similar to that of SAHA yet without significant cytotoxicity for normal IMR-90 cells . - pubmed
Age - related probability of contralateral processus vaginalis patency in children with unilateral inguinal hernia . - pubmed
PURPOSE : Contralateral groin exploration with closure of a patent processus vaginalis ( PPV ) in children with a unilateral inguinal hernia remains controversial . - pubmed
Quality - of - life scores in neurogenic thoracic outlet syndrome patients undergoing first rib resection and scalenectomy . - pubmed
Anisometropia and aniso - astigmatism were more common in 12- to 13 - year - old children with hyperopia & gt;=+2 DS . - pubmed
A 13 mo old spayed female mixed - breed dog presented in a nonambulatory state that was attributed to severe myoclonus secondary to distemper . - pubmed
The authors hypothesized that mitigating the myoclonus would help the dog become ambulatory and expedite convalescence . - pubmed
Those injections reduced the myoclonus , helping the dog become ambulatory and attaining a comfortable , functional state . - pubmed
We describe herein a rare case of a primary primitive neuroectodermal tumor ( PNET ) in the mediastinum of a 75 - year - old man . - pubmed
RESULTS : Thirty - six patients underwent caudate lobe resection for cholangiocarcinoma ( 47.2 % ) , metastatic colorectal cancer ( 36.1 % ) , hepatocellular carcinoma ( 8.3 % ) , or benign disease ( 8.3 % ) . - pubmed
CONCLUSIONS : With appropriate patient selection , caudate lobe resection is an effective component of surgery for hepatic disease . - pubmed
Although levothyroxine , a thyroid hormone , is the treatment of choice for hypothyroidism , a significant number of patients on thyroid hormone replacement therapy report not feeling well despite having thyroid function tests within the healthy range . - pubmed
Based on our hypothesis , we started treating the fatigue in patients affected by Hashimoto ' s thyroiditis and taking a thyroid hormone with thiamine . - pubmed
This is a report of the outcomes of three cases in which the fatigue component reported by patients with Hashimoto ' s thyroiditis was treated with thiamine . - pubmed
DESIGN : Three patients on thyroid hormone replacement because of Hashimoto ' s thyroiditis were treated for the fatigue component of the disease from May to July 2011 . - pubmed
Carpal tunnel syndrome with thenar atrophy : evaluation of the pinch and grip strength in patients undergoing surgical treatment . - pubmed
This aim of this study was to evaluate the progression of grip , tip pinch , key ( lateral ) pinch , and tripod pinch strengths in patients suffering from carpal tunnel syndrome with thenar atrophy following surgery . - pubmed
Between October 2008 and May 2010 , 46 patients ( 49 hands ) with carpal tunnel syndrome associated with thenar atrophy underwent surgery . - pubmed
Protective effects of selenium on mercury induced immunotoxic effects in mice by way of concurrent drinking water exposure . - pubmed
To explore the effects of Se on Hg - induced immunotoxicity , female Balb / c mice were exposed to HgCl2- or MeHgCl - contaminated drinking water ( 0.001 , 0.01 , and 0.1 mM as Hg ) with coexisting Na2SeO3 at different Se / Hg molar ratios ( 0:1 , 1/3:1 , 1:1 and 3:1 ) . - pubmed
Shiga toxin - producing Escherichia coli ( STEC ) strains are commonly found in cattle gastrointestinal tracts . - pubmed
BACKGROUND : Lead malfunction is an important cause of morbidity and mortality in patients with an implantable cardioverter - defibrillator ( ICD ) . - pubmed
Previous computed tomography - based work on humans who underwent imaging before and directly after aortic dissection onset has shown an average 30 % increase in the ascending aortic diameter with acute dissection . - pubmed
METHODS : From 2002 to 2013 , 495 patients presented with acute type A aortic dissection to 1 center . - pubmed
A 34 - year - old full - term pregnant woman presented with abruptly aggravating dyspnea . - pubmed
This is the first report of a patient with peripartum cardiomyopathy who had a successful delivery with the support of ECMO , demonstrating that ECMO can serve as a rescue therapy , not only treating peripartum cardiomyopathy but also permitting a safe delivery . - pubmed
The type strain of M. - pubmed
Immunohistochemical and molecular study on the protective effect of curcumin against hepatic toxicity induced by paracetamol in Wistar rats . - pubmed
Therefore , this study was conducted to examine the molecular levels of the protective effect of curcumin on paracetamol overdose induced hepatic toxicity in rats . - pubmed
Control group , administered corn oil ; curcumin group , administered curcumin ( 400 mg / kg BW daily intra - gastric ) dissolved in corn oil ; paracetamol group , administered corn oil with a single dose of paracetamol ( 500 mg / kg BW intra - gastric ) and protective group , administered curcumin with a single dose of paracetamol . - pubmed
CONCLUSION : The results clarified the strong protective effect of curcumin on paracetamol induced hepatic toxicity in rats at the immunohistochemical and molecular levels . - pubmed
Brain structure in people at ultra - high risk of psychosis , patients with first - episode schizophrenia , and healthy controls : a VBM study . - pubmed
We used high - resolution MRI and voxel - based morphometry ( VBM8 ) to analyze grey matter differences in 43 ultra high - risk subjects for psychosis ( meeting ARMS criteria , identified through CAARMS interviews ) , 24 antipsychotic - naive first - episode schizophrenia patients and 49 healthy controls ( groups matched for age and gender ) . - pubmed
, first - episode schizophrenia patients had reduced regional grey matter in left prefrontal , insula , right parietal and left temporal cortices , while the high - risk group showed reductions in right middle temporal and left anterior frontal cortices . - pubmed
This plant , whose infusions or complex mixtures of its metabolites are the basis for many formulas sold in pharmacies and by herbalists , has anti - diabetic and slimming effects . - pubmed
For bioactivity assay , compounds 4 - 7 showed significant cytotoxicity toward murine colorectal CT26 and human leukemia K562 cancer cell lines with IC50 values ranging from 6.7 to 15.3 microM and from 12.5 to 23.1 microM , respectively . - pubmed
The objective of this study was to determine whether MaR1 is effective at limiting lung inflammation associated with acute and repetitive exposures to DE in an established murine model of inhalant dust exposures . - pubmed
Fighting Cancer on All Fronts : Stereotactic Radiosurgery and the Role for Aggressive Primary Treatment in Non - Small Cell Lung Cancer Patients with One Brain Metastasis . - pubmed
BACKGROUND : We performed an updated meta - analysis of randomized placebo - controlled trials testing memantine monotherapy for patients with Alzheimer ' s disease ( AD ) . - pubmed
CONCLUSIONS : Memantine monotherapy improved cognition , behavior , activities of daily living , global function , and stage of dementia and was well - tolerated by AD patients . - pubmed
Partial resistance to homologous challenge infections of the digenean Echinostoma caproni in ICR mice . - pubmed
In the present paper , we analyse the effect of a primary infection of ICR mice with Echinostoma caproni ( Trematoda : Echinostomatidae ) on the generation of resistance against homologous challenge infections . - pubmed
Here , the effect of the response generated against a primary infection with E. - pubmed
caproni and the results obtained showed that primary infection induces partial resistance against subsequent homologous infections in ICR mice . - pubmed
HIV - infected patients were randomized to add maraviroc ( 41 patients ) or placebo ( 44 patients ) to their cART regimen for 48 weeks . - pubmed
We examined relative survival , the ratio of survival in cervical cancer patients to matched controls over time . - pubmed
Changes in stage - specific relative survival for patients with cervical cancer compared to the general population matched by age , race , and calendar year were examined over time . - pubmed
There were no statistically significant improvements in relative survival over time for women with stage IV tumors . - pubmed
CONCLUSION : Relative survival has improved over time for women with stage I - III cervical cancer , but has changed little for those with metastatic disease . - pubmed
We assessed regional amyloid load using AV45 - PET , neuronal metabolism using FDG - PET , and gray matter volume using structural MRI in 473 participants from the Alzheimer ' s Disease Neuroimaging Initiative , including preclinical , predementia , and clinically manifest AD stages . - pubmed
25 wk of gestation in human pregnancy , rescues early origins of cardiovascular dysfunction during hypoxic development . - pubmed
METHODS : Between January 2009 and December 2012 , 38 patients with combined injury of meniscus bucket handle tear underwent arthroscope surgery by the method of both side stereo suture . - pubmed
The aim of this work was to find out if there is a statistically significant correlation between these different predictors and their correlation with the central corneal thickness for refractive non - keratoconic Egyptian patients trying to achieve a better decision and avoiding ectasia . - pubmed
METHODS : This case - control study involved 142 eyes ( of 77 patients with various refractive errors ) arriving at the refractive surgery unit in the Research Institute of Ophthalmology in Giza ( Egypt ) in 2014 - 2015 seeking excimer laser ablation . - pubmed
METHODS : From September 1991 to December 2002 , 2150 patients with multivessel coronary artery disease underwent isolated myocardial revascularization with BIMA grafting . - pubmed
miR-125b expression in the sputum of 50 asthmatic children and 50 age- and sex - matched healthy controls were assessed by quantitative RT - PCR ( qRT - PCR ) . - pubmed
Additionally , intranasal delivery of miR-125b mimic in mice was performed to study its effects on house dust mite - induced allergic airway inflammation mouse models . - pubmed
We found that miR-125b expression was decreased in the sputum of the asthmatic patients especially in eosinophilic asthma . - pubmed
BACKGROUND : A role of Chlamydia trachomatis in HPV - induced cervical carcinogenesis has been reported for cervical cancer but studies on cervical adenocarcinoma are limited . - pubmed
METHODS : A total of 1,553 cervical smears taken up to 26 years before diagnosis in a large population - based nested case - control study of cervical adenocarcinoma ( AC , 132 cases with matched controls ) , and adenocarcinoma in situ ( AIS , 159 cases with matched controls ) were tested for C. - pubmed
MATERIAL AND METHODS : We collected data from 153 patients with MS . - pubmed
Patients filled out the Pittsburgh Sleep Quality Index ( PSQI ) , the Hospital Anxiety and Depression Scale , and one item of the Short Form-36 regarding pain . - pubmed
Potential immunological markers for diagnosis of human strongyloidiasis using heterologous antigens . - pubmed
Strongyloides venezuelensis is a parasitic nematode of rodents that is frequently used to obtain heterologous antigens for immunological diagnosis of human strongyloidiasis . - pubmed
venezuelensis for immunodiagnosis of human strongyloidiasis . - pubmed
venezuelensis antigens for use in immunodiagnostic assays for human strongyloidiasis . - pubmed
Among these , two compounds 35 , and 36 showed a significant inhibition in male Wistar rats , and identified as potential lead molecules for anti - hyperuricemic drug development . - pubmed
Consumers were unable to detect flavor differences in oil - soluble fortified milks , but trained panelists documented a faint carrot flavor in oil - soluble fortified skim milks at higher vitamin A concentrations ( 3,000 - 6,000 IU ) . - pubmed
Therefore , the purpose of this study was to quantify balance performance in both ankle osteoarthritis patient groups . - pubmed
Twenty - two unilateral and twenty - one bilateral ankle osteoarthritis patients performed three 10 - s quiet standing trials with their feet together . - pubmed
Humanin rescues cultured rat cortical neurons from NMDA - induced toxicity through the alleviation of mitochondrial dysfunction . - pubmed
Video - assisted thoracic surgery is associated with better short - term outcomes than open thoracotomy in adult patients with intralobar pulmonary sequestration . - pubmed
OBJECTIVES : This study was aimed to investigate potential benefits of thoracoscopic surgery for intralobar pulmonary sequestration in adult patients in terms of short - term surgical outcomes when compared with open surgery . - pubmed
CONCLUSIONS : Video - assisted thoracic surgery is associated with less intraoperative bleeding and shorter postoperative hospital stay than is open thoracotomy in surgical resection of intralobar pulmonary sequestration in adult patients . - pubmed
Furthermore , using a combination therapy of the chelating agent deferoxamine ( DFX ) and Trolox , liver injury and oxidative stress markers were also reduced in iron overloaded mice . - pubmed
We analyzed 73 tumour samples from 21 patients and compared cellular density , cell proliferation , and the degree of vascularity . - pubmed
PURPOSE : Evaluating the role of surgery and the extent of tumor resection on the outcome of patients with localized initially unresectable neuroblastoma ( NB ) . - pubmed
PATIENTS AND METHODS : This was a retrospective case review study including patients with localized initially unresectable NB . - pubmed
RESULTS : A total of 202 patients with NB were included . - pubmed
Fifty - five ( 57.2 % ) were in good response after primary chemotherapy and 41 patients ( 42.7 % ) had persisting IDRFs , nine of them had biopsy only , and a follow - up strategy was considered in the other 32 patients . - pubmed
CONCLUSION : In children with localized initially unresectable NB , surgical resection was the only significant risk factor associated with better survival . - pubmed
Skin and soft tissue infection was diagnosed in 1 of 22 patients ( 4.55 % ) . - pubmed
Introduction : Treatment of infection within bone is difficult , and conventional surgical treatment brings intense pain to the patients physically and mentally . - pubmed
The lure of death : suicide and human evolution . - pubmed
At some point in evolutionary history , human beings came to understand , as no non - human animals do , that death brings to an end a person 's bodily and mental presence in the world . - pubmed
In almost half of the patients , type I cryoglobulinemia is characterized by severe cutaneous involvement . - pubmed
PATIENT CONCERNS : A 71 - year - old man comes to our observation because of the onset of persistence of paresthesia and painful acrocyanosis in the fingers and toes . - pubmed
Impact of induction regimen and allogeneic hematopoietic cell transplantation on outcome in younger adults with acute myeloid leukemia with a monosomal karyotype . - pubmed
Monosomal karyotype confers a poor prognosis in patients with acute myeloid leukemia . - pubmed
Here , we determined the impact of the type of remission - induction chemotherapy and the impact of having a donor in younger acute myeloid leukemia patients with a monosomal karyotype included in two phase III trials . - pubmed
monnieri extracts were investigated in Vibrio harveyi mutagenicity assays . - pubmed
METHODS : We performed electroanatomic mapping and RFCA in the left ventricles of 8 swine with myocardial infarction . - pubmed
Currently , imported and exported tomato fruit are not monitored for TYLCV infection because they are not considered to represent a potential risk as a virus source for whiteflies . - pubmed
We present the clinical and radiological findings of two 5 - year - old children with pseudomalignant MO due to prolonged immobilization . - pubmed
Vaccines for Pseudomonas aeruginosa have been of longstanding interest to immunologists , bacteriologists , and clinicians , due to the widespread prevalence of hospital - acquired infection . - pubmed
Comparative proteomic analysis of saliva from dogs with and without obesity - related metabolic dysfuntion . - pubmed
Dogs develop only some of the components of the human metabolic syndrome ( MetS ) . - pubmed
Thus , in order to study possible MetS - related alterations in dogs , human MetS criteria were adapted to define canine MetS or so - called obesity - related metabolic dysfunction ( ORMD ) . - pubmed
The main objective of this study was to identify changes in the salivary proteome of obese dogs with ORMD in comparison with obese dogs without ORMD which may constitute potential salivary biomarkers for assessing ORMD . - pubmed
In a first phase , 12 adult obese dogs with ORMD ( N = 6 ) and without ORMD ( N = 6 ) were included in the study . - pubmed
Subsequently , and with the aim of validating and strengthening the results , additional 12 obese dogs ( 6 with and 6 without ORMD ) were tested in an independent experiment following the same protocol . - pubmed
SIGNIFICANCE : This is the first study evaluating proteomes of saliva in dogs , as a non invasive sample , in order to increase knowledge about the metabolic / physiopathological changes related to obesity - related metabolic dysfunction ( ORMD ) together with the identification of potential biomarkers for its diagnosis . - pubmed
As approximately 20 % of dogs with naturally occurring obesity were described to suffer ORMD associated with insulin resistance and hypoadiponectinemia , the fact that indicate possible links between ORMD and associated diseases . - pubmed
METHODS : Retrospective chart review of veterans with chronic hepatitis C infection who received more than 1 week and up to 6 weeks ( 8 - 42 days ) of DAA therapy with the initiation day between January 1 , 2015 , and October 15 , 2018 , at Bay Pines Veterans Affairs Healthcare System . - pubmed
Clinical case : 25 - year - old woman who presented oligomenorrhea , increased weight , decreased visual acuity and chronic headache . - pubmed
Transsphenoidal surgery was performed with complete resection of lesion , and during short - term follow - up it was observed recurrence , which is why the patient needed two more interventions . - pubmed
Future evaluation of the vagus nerve and brain of animals with colitis will be key to assess the contribution of colitis - induced ENS alpha - syn pathology to PD - like pathology in the brain . - pubmed
Four primiparous and 16 multiparous mid - lactating dairy cows were assigned according to milk yield , body weight ( BW ) , days in milk , and parity into 2 groups and fed 1 of the 2 diets for 34 d. The first 13 d were used for diet adaption , followed by data collection of nutrient intake , chewing activity , sorting behavior , milk production , and nutrient digestibility for the last 21 d of the experiment . - pubmed
Beneficial effects of dapsone on ischemia / reperfusion injury following torsion / detorsion in ipsilateral and contralateral testes in rat . - pubmed
Therefore , the aim of this study was to investigate the influence of dapsone on ischemia / reperfusion ( I / R ) injury in bilateral testes after unilateral testicular torsion / detorsion ( T / D ) in rats . - pubmed
It was concluded that dapsone had a protective impact on I / R injury in the rat model of testicular T / D , and this effect was most likely induced by anti - inflammatory and anti - oxidative properties of dapsone . - pubmed
Here we report 2 unusual cases involving very young children with pneumorrhachis secondary to pneumomediastinum and present a review of the relevant literature . - pubmed
Case 1 involved a 4 - year - old girl who presented with wheezing , violent coughing , and dyspnea associated with bronchiolitis . - pubmed
Case 2 involved a 3 - year - old boy who presented with wheezing , violent coughing , and dyspnea associated with interstitial pneumonia possibly caused by graft - versus - host disease with human herpesvirus 6 infection after allogeneic hematopoietic stem cell transplantation . - pubmed
Because pneumorrhachis is rare in children and neurological sequelae may be difficult to identify , close clinical , and radiographic observations are necessary . - pubmed
Identification and complete - genome phylogenetic analysis of an epizootic hemorrhagic disease virus serotype 7 strain isolated in China . - pubmed
An epizootic hemorrhagic disease virus ( EHDV ) strain designated YN09 - 04 was isolated from sentinel cattle in China . - pubmed
These results suggest that the genome of YN09 - 04 likely originated from a reassortment event between EHDV strains that were similar to the current Japanese and Australian strains and that YN09 - 04 and some EHDVs from Japan and Australia share the same ancestors . - pubmed
MATERIALS AND METHODS : We enrolled asymptomatic diabetic patients as well as prediabetic and normoglycemic subjects to test sensory nerve excitability , and we analyzed those findings and their correlation with clinical profiles . - pubmed
METHODS : A multi - institution , prospective pilot study of patients with first presentation for PSP at 9 children 's hospitals was performed . - pubmed
JA - Ile - macrolactone 5b - treated tea plants significantly inhibited the larvae weight gain of Ectropis obliqua larvae and the lesions caused by Colletotrichum camelliae . - pubmed
obliqua , but it did not directly influence the infection of C. - pubmed
Tuberculosis is a very serious respiratory infectious disease , caused by the bacillus Mycobacterium tuberculosis , which generates a relevant societal and clinical burden . - pubmed
Firstly , the TCA cycle was rewired for alpha - KG production starting from pyruvate , and the engineered strain E. - pubmed
A 24 - year - old woman presented with subdural hemorrhage , and subsequent radiology depicted an osteolytic mass - like lesion in the sphenoid bone . - pubmed
DESIGN , SETTING , AND PARTICIPANTS : Costs for surgical care for consecutive patients with localized prostate cancer treated from November 2018 to November 2019 were itemized and evaluated . - pubmed
Texture analysis on bi - parametric MRI for evaluation of aggressiveness in patients with prostate cancer . - pubmed
METHODS : A total of 116 patients who had been confirmed as prostate adenocarcinoma by radical prostatectomy or biopsy were divided into a training ( n = 65 ) and a validation dataset ( n = 51 ) . - pubmed
Dynamic organ preservation techniques , modulation of ischemia - reperfusion and preservation injury , and allograft therapies are in the spotlight of scientific interest in an effort to improve allograft utilization and patient outcomes in KT . - pubmed
Androgens by immunoassay and mass spectrometry in children with 46,XY disorder of sex development . - pubmed
METHODS : Nineteen patients with 46,XY DSD were evaluated ; all of them were prepubertal and non gonadectomized . - pubmed
PARTICIPANTS : Ten lean and obese healthy men . - pubmed
INTRODUCTION : Weekly iron - folic acid ( IFA ) supplements are recommended for all menstruating women in countries where anaemia prevalence is > 20 % . - pubmed
Including folic acid might reduce the risk of a neural tube defect ( NTD ) should a woman become pregnant . - pubmed
Moreover , women in the 2.8 mg group were seven times ( RR 7.3 , 95 % CI 3.9 to 13.7 ; p<0.0001 ) more likely to achieve an RBC folate > 748 nmol / L , a concentration associated with a low risk of NTD , compared with the 0.4 mg group . - pubmed
RETRACTION NOTICE : Exosomes promote restoration after an experimental animal model of intracerebral haemorrhage . - pubmed
For instance , folding - deficient variants of the human transporters for dopamine or GABA lead to infantile parkinsonism / dystonia and epilepsy , respectively . - pubmed
Candida parapsilosis complex infection in a cutaneous lesion from a dog : Spotlight on an opportunistic pathogen of potential increasing importance . - pubmed
Marked pyogranulomatous inflammation and fungal organisms were present , identified as Candida parapsilosis complex by MALDI - ToF following fungal culture . - pubmed
BACKGROUND : Regorafenib has been approved among the treatment options for patients with advanced stage colorectal cancer ( CRC ) , hepatocellular carcinoma ( HCC ) , and gastrointestinal stromal tumors ( GIST ) . - pubmed
Toxicity and intolerability of regorafenib lead to treatment discontinuation in nearly a quarter of patients . - pubmed
PURPOSE : The purpose of this study was to evaluate etiologies , management , and outcomes of patients with giant retinal tears ( GRTs ) undergoing primary surgery at a tertiary referral center . - pubmed
[ Skin diseases in workers coming in contact with inhibitors of the atmospheric corrosion of metals ] . - pubmed
A statistically significant prolongation of latency of the main deflections ( N1 , P max and N2 ) was observed in the group of 14 patients with optic nerve damage , while in 10 patients with lesions above the chiasma different , often normal responses were obtained . - pubmed
The author reviewed electrocardiographic records of 150 patients with acute stroke and 150 age- and sex - matched controls , to assess the relative frequencies of ECG abnormalities among the pathophysiologic categories of stroke , and to distinguish new abnormalities at the time of the stroke from those noted on prior tracings . - pubmed
Of the 150 patients with stroke , 138 ( 92 % ) showed ECG abnormalities . - pubmed
Patients with cerebral embolus had a significantly increased frequency of atrial fibrillation ( 9 patients , 47 % ) ; and with subarachnoid hemorrhage an increased frequency of QT prolongation ( 20 , 71 % ) and sinus arrhythmia ( 5 , 18 % ) . - pubmed
Stroke patients had an increased frequency of pathologic Q waves ( 30 patients , 20 % ) and left ventricular hypertrophy ( 39 , 26 % ) , but these were not new findings at the time of the stroke . - pubmed
Tympanic membrane perforations in cats : configurations of losses with and without ear canal extensions . - pubmed
Among 140 patients with hydatid echinococcosis of the liver complications were noted in 58 cases : suppuration of the cyst - in 38 ( 27.1 % ) , cyst rupture in the anterior abdominal wall and abdominal cavity - in 4 ( 2.8 % ) , in bile ducts - in 10 ( 7.1 % ) , its rupture into the right lung lower lobe , calcification of the cyst was noted in 4 patients ( 2.8 % ) . - pubmed
Urodynamic investigations were performed in 9 males , suffering from dysfunction of the bladder neck ( detrusor bladder neck dyssynergia ) . - pubmed
The parameters of micturition were compared with the values in normal males and in patients with prostatic obstruction . - pubmed
Vascular proliferation and mononuclear cell infiltration are prominent changes observed in synovium from actively inflamed joints of patients with rheumatoid arthritis . - pubmed
Eight ( 6.6 % ) patients had postoperative hematomas larger than 4 cm in diameter , which delayed the start of RT by 2 to 3 weeks . - pubmed
Eighty - two patients were studied ; 40 were normotensive and 42 had hypertension currently controlled by pharmacological therapy . - pubmed
In antiinflammatory action , its half effective dose ( ED50 ) was 0.12 mg / kg with the model of croton oil induced ear swelling of mice . - pubmed
In this study , eighty limbs ( 71 patients ) with clinically suspected deep venous thrombosis ( DVT ) were investigated by both venography and Doppler ultrasonography . - pubmed
A sample of 700 female epileptic outpatients was examined between 1985 and 1987 . - pubmed
A 37 - year - old man presented to the emergency department after an attempt to self - treat his priapism with saltpeter ( K+NO3 ) . - pubmed
[ Recurrent ventricular fibrillation in a patient with angiographically normal coronary arteries and intermittent ST segment elevation ] . - pubmed
We report on a patient who was admitted to the hospital because of severe angina pectoris . - pubmed
Amiprilose hydrochloride , a 3 - substituted glucose derivative , was found to inhibit the proliferation of human fibroblasts and keratinocytes originating from psoriatic lesions . - pubmed
Noradrenergic involvement in pinealectomy induced convulsions in gerbils . - pubmed
Gerbils treated with various noradrenergic compounds were pinealectomized ( PINX ) or sham - operated ( SHAM ) and observed for convulsive activity . - pubmed
Although declines in cortical and hypothalamic norepinephrine content were found after alpha - methylparatyrosine ( alpha MPT ) or PINX , treatment with alpha MPT did not produce convulsions in SHAM gerbils or in gerbils which were PINX one week earlier . - pubmed
Likewise , alpha MPT did not increase the number or severity of convulsions observed in acutely PINX gerbils . - pubmed
Treatment with propranolol or isoproterenol did not have any effect on convulsive activity of PINX gerbils , except that isoproterenol increased the excitability of all the gerbils . - pubmed
Avoiding splenectomy in the treatment of children with splenic injury . - pubmed
Ninety - two consecutive patients with traumatic rupture of the spleen were studied . - pubmed
A third of the patients in each group had associated injuries , renal injury being the most common intraabdominal lesion . - pubmed
Among the 40 patients who were treated conservatively , a biphasic course was seen in 23 : one or two days after the accident a period of increased pulse rate , fever and increased abdominal tenderness and pain followed , but no evidence for a delayed rupture was found . - pubmed
In the 19 patients evaluated , no thromboses were detected nor any narrowing greater than 10 % of proximal diameter as seen by angiography . - pubmed
Effects of antidepressants on alcohol - induced gastric mucosal injury in rats . - pubmed
Results showed marked glucose intolerance with peak value 60 min after glucose load in cirrhotic patients with normal fasting blood glucose . - pubmed
These concentrations were compared with the levels obtained by infusion to the dog , which cause serious cardiac disorders with 6,000 to 8,000 ng.ml-1 levels , and elicit ventricular fibrillation with 8,000 to 10,000 ng.ml-1 . - pubmed
[ Treatment of acute myeloblastic leukemia in elderly patients with low - dose cytosine arabinoside ] . - pubmed
Forty - eight patients , aged from 65 to 88 years , presenting with de novo acute myelogenous leukemia were treated with a low - dose cytarabine regimen ( 10 mg / sq.m subcutaneously 12 - hourly for 15 to 28 days ) . - pubmed
Bleeding occurred in 28 patients and fever was noted , also in 28 patients . - pubmed
Four patients died of infection during induction treatment . - pubmed
It is concluded that low - dose cytarabine is an alternative to intensive chemotherapy in elderly patients with acute myelogenous leukemia . - pubmed
Abomasal fistulas in dairy cows . - pubmed
Abomasal fistulas were corrected surgically in 9 adult Holstein cows . - pubmed
All fistulas were in the right paramedian area and were draining blood and/or ingesta from necrotic abomasal tissue ( 8 cows ) or ruminal tissue ( 1 cow ) . - pubmed
Surgery was performed immediately in cows with consistent hemorrhage from the fistulated tissue ( 4 cows ) . - pubmed
Surgery was delayed to reduce rumen contents if bleeding was absent or considered negligible ( 4 cows ) or to stabilize the patient ( 1 cow ) . - pubmed
Outcome following the fistula resection was successful in the 7 cows discharged from the clinic . - pubmed
Invasion of erythrocytes by Plasmodium falciparum malaria parasites : evidence for receptor heterogeneity and two receptors . - pubmed
Plasmodium falciparum malaria parasites with different capabilities of invading sialic acid - deficient erythrocytes were identified . - pubmed
P falciparum malaria parasites probably possess two receptors : one that binds to a sialic acid - dependent ligand and another that binds to a sialic acid - independent ligand . - pubmed
Out of a series of 900 biopsy - proven cases of skeletal " fibroxanthoma " ( nonossifying fibroma , fibrous cortical defect ) , we studied 72 patients with more than one lesion . - pubmed
[ Nonsurgical treatment of pulmonary valve stenosis using balloon valvuloplasty in children ] . - pubmed
We reviewed the manner of presentation and tumor stage in 56 consecutive patients with renal cell carcinoma treated surgically between 1961 and 1973 ( group 1 ) and compared them to 46 patients treated similarly between 1980 and 1984 ( group 2 ) . - pubmed
[ Cardiac output and total peripheral resistance in experimental arterial hypertension in dog ] . - pubmed
Antitumor activity of vinzolidine in the human tumor clonogenic assay and comparison with vinblastine . - pubmed
Vinzolidine ( VZL ) , a semisynthetic vinblastine ( VLB ) derivative , was tested against a variety of solid tumors in the human tumor clonogenic assay ( HTCA ) . - pubmed
The genotoxicity of 4,4 '- methylenebis-2 - chloroaniline in rat , mouse , and hamster hepatocytes . - pubmed
The case of prostatic adenocarcinoma described has only been reported in one other nonhuman primate . - pubmed
In the mouse repeated high doses ( 480 mg / kg / day ) cause paralysis of the hind limbs but there is no effect on fertility . - pubmed
A case report is presented in which a patient with well - documented pigmented villonodular synovitis sustained a disruption of the popliteal artery without evidence of penetration of the posterior capsule . - pubmed
The article discusses the results of endoscopic examination of 44 children with extrahepatic portal hypertension before and after various types of portocaval shunting . - pubmed
Effect of Septilin , an ayurvedic formulation proven to be effective in the therapy of chronic infections , was investigated on the phagocytic system and humoral response in rats and mice . - pubmed
coli - induced abdominal sepsis in normal mice and in Staphylococcus aureus - induced sepsis in neutropenic mice . - pubmed
Contents of trace elements in the hair of aplastic anemia patients and their treatment based on an overall analysis of symptoms and signs . - pubmed
The content of 12 trace elements in the hair of 20 aplastic anemia patients was determined and compared with that of normal subjects as control . - pubmed
In summary , the mechanism of sudden death in this patient was revealed by ambulatory ECG monitoring , and the involvement of neural and myocardial factors are proposed . - pubmed
Growth of human myeloid leukemias in the human marrow environment of SCID - hu mice . - pubmed
We describe here an application of this animal model , the SCID - hu mouse , to the study of human myeloid leukemias . - pubmed
BM cells from 8 patients with various types of myeloid leukemias were injected directly into human bone grafts in the SCID - hu mouse . - pubmed
Thus , human myeloid leukemia cells could be reproducibly propagated in the human marrow environment in SCID - hu mice . - pubmed
The differentiation of promyelocytic leukemia cells in the SCID - hu mice was induced by all - trans retinoic acid , suggesting that the biologic features of the leukemia cells were maintained as well . - pubmed
This model may provide a useful tool for studying the biology of human myeloid leukemia as well as for evaluating new therapeutic modalities for myeloid leukemias . - pubmed
The thrombi formed by batroxobin were rapidly lysed in control animals , while the rate of lysis was markedly attenuated in rats given endotoxin . - pubmed
SUBJECTS : 66 overweight men ( mean age 43.4 + /- 5.7 y , BMI 29.0 + /- 2.6 kg / m2 ) . - pubmed
Intravenous infusion of diltiazem causes uricosuria with concomitant hypouricemia in rats . - pubmed
Immunophenotyping of human HT29 colon cancer cell primary tumours and their metastases in severe combined immunodeficient mice . - pubmed
The immunophenotype of HT29 human colon cancer cells implanted into severe combined immunodeficient mice was assessed in primary tumours and their metastases in the lungs using an indirect immunohistochemical method . - pubmed
CLINICAL PRESENTATION : A 41 - year - old man was admitted with a 3 - year history of low back pain and sciatica . - pubmed
Therefore , we decided to operate on the patient having made a diagnosis of lumbar disc disease . - pubmed
CONCLUSION : The patient was immediately relieved of pain and was discharged on the 7th day after the operation with normal muscle strength . - pubmed
It seems probable that in some patients with " failed back syndrome , " intraradicular or intradural disc herniation is the cause of failure . - pubmed
All patients had chronic HCV infection with confirmation of chronic hepatitis on liver biopsy . - pubmed
Although the plasma half - lives are longer and marrow dose higher for radiolabeled huBrE-3 compared with the murine construct , the excellent tumor localization , good tumor dosimetry , and low immunogenicity support the use of 90Y - huBrE-3 antibody for radioimmunotherapy of breast cancer . - pubmed
PURPOSE : To measure under carefully controlled conditions the effects in the rabbit eye of commonly used therapeutic agents for glaucoma . - pubmed
However , rapid and high cytotoxic activities against HCV core were not only detected after immunization with peptides containing the CTL epitope but also as a result of infection with recombinant vaccinia virus carrying the HCV core gene after immunization with the Th epitope alone . - pubmed
The risk of duodenal ulcer is enhanced by infection with proinflammatory H. - pubmed
Progressive damage to the duodenum promotes gastric metaplasia , resulting in sites for H. - pubmed
OBJECTIVE : To determine the prognosis and distribution of ischemic injuries caused by inappropriate bandaging of the lower limb in dogs and cats . - pubmed
ANIMAL POPULATION : Eleven client - owned animals , including 9 dogs and 2 cats with a history of injuries consistent with incorrect application of a bandage . - pubmed
METHODS : Medical records for dogs and cats referred to the Queen 's Veterinary School Hospital with limb wounds between 1995 and 1999 were reviewed for clinical history and referring veterinary surgeons ' reports , indicating that the injury was directly related to the application of a bandage to the limb . - pubmed
Of the 11 animals , 5 required full - thickness skin grafts , 3 had to have digits amputated , and 2 required limb amputations . - pubmed
PURPOSE : To present the ophthalmic manifestations of patients with Gilles de la Tourette syndrome ( GTS ) . - pubmed
METHODS : Sixteen children ( average age 11.5 years ) , with multiple motor and vocal tics , with a diagnosis of GTS , were included in this study . - pubmed
Eleven patients ( 68 % ) had eye tics ; nine had clonic blepharospasm and two had involuntary gaze deviations . - pubmed
Four cooperative children underwent visual field examination with Goldmann perimeter , no visual field defect was detected . - pubmed
Three patients had strabismus ( one alternating exotropia and two partially accommodative esotropia ) . - pubmed
The symptoms improved considerably in 82 % of the patients with eye tics on treatment with a neuroleptic ( pimozide ) . - pubmed
Ophthalmologists should consider a diagnosis of GTS in the absence of any organic eye pathology that may cause blepharospasm and refer these cases to a child psychiatrist . - pubmed
OBJECTIVES : To investigate the clinical profiles of subjects referred for allergy evaluation ; to prospectively reduce the frequency of evaluation by assessing the persistence , during clinical use , of non - reactivity to contaminant / additive - free mepivacaine ; and to determine the usefulness of a diagnostic protocol involving patch testing . - pubmed
True allergic reactions to contaminant / additive - free mepivacaine were not observed in our patient series . - pubmed
The authors then applied these methods to [ ( 11 ) C ] MP4A PET data in 12 healthy subjects and 26 patients with Alzheimer disease ( AD ) using the cerebellum as the reference region . - pubmed
An out - patient second - line chemotherapy with gemcitabine and vinorelbine in patients with non - small cell lung cancer previously treated with cisplatin - based chemotherapy . - pubmed
Thirty - nine patients with advanced non - small cell lung cancer , refractory or resistant to platinum or taxanes derivatives were treated on an out - patient basis with vinorelbine 25 mg / m2 intravenous ( I.V. ) - pubmed
All 39 patients were assessable for toxicity and 35 were assessable for response . - pubmed
Clinical benefit response including improvement of PS , dyspnea and anorexia , pain and cough reduction and cessation of hemoptysis and fever was observed in 10 % to 50 % of patients . - pubmed
Grade 3/4 neutropenia occurred only in 2 ( 5.2 % ) patients . - pubmed
No patient experienced grade 3/4 anaemia or thrombocytopenia . - pubmed
One patient experienced grade 4 fatigue and stopped the treatment . - pubmed
Nausea / vomiting , fatigue , neurotoxicity , diarrhea and fever were mild in the majority of patients and did not result in any clinically significant problem . - pubmed
BACKGROUND : The purpose of this historical cohort study was to compare the speech development of children with three types of cleft palate while controlling for some confounding factors . - pubmed
METHODS : Subjects included 28 children with bilateral cleft lip and palate ( BCLP ) , 74 with unilateral cleft lip and palate ( UCLP ) , 33 with isolated cleft palate ( ICP ) , and 168 normal control children . - pubmed
Children with cleft palate attended a speech clinic in Fukuoka , had attained adequate velopharyngeal function after palatoplasty carried out within 18 months after birth , and had no syndromic diseases , persistent hearing loss , mental retardation , or central nervous system problems . - pubmed
RESULTS : Children with BCLP began using two - word sentences later than other children ( 3 months , P<0.01 ) . - pubmed
Children with BCLP had lower verbal scores on the Wechsler Preschool and Primary Scale of Intelligence ( WPPSI ) than other children ( 12.4 - 14.9 points , P<0.01 ) . - pubmed
CONCLUSIONS : The results of this research indicate the following : speech development of children with ICP and UCLP was similar to that of normal children ; however , speech development of children with BCLP was delayed compared with other children with or without cleft palate . - pubmed
When the enzyme is provided by the infusion of normal plasma , these patients remain free of TTP symptoms for about three weeks . - pubmed
Extent and severity of atherosclerotic vascular disease in patients undergoing coronary angiography -- the Kuwait Vascular Study . - pubmed
The presence of AND Cent Lec virus in rodent populations of the study area , which is responsible of HPS cases in central Argentina , suggests that human populations are at risk of HPS disease , although there were not reported cases of this disease until today . - pubmed
BACKGROUND : The immediate result of successful revascularisation of the myocardium is the improvement of perfusion ( and in patients with depressed ventricular function , functional recovery is expected as an effect of coronary flow improvement ) . - pubmed
Eighty - one percent of patients had a history of myocardial infarction , the number of stenosed main coronary arteries was 2.3 + /- 0.6 per patient , and the left ventricle ejection fraction was 18 - 70 % ( mean 46 + /- 14 % ) . - pubmed
Protection from infectious bursal disease virus ( IBDV)-induced immunosuppression by immunization with a fowlpox recombinant containing IBDV - VP2 . - pubmed
To facilitate clinical investigation of metabolic acidosis , a high - performance liquid chromatographic method was adapted and validated for the chiral separation of D -(- ) and L -(+)- lactic acid in calf feces , rumen fluid and urine . - pubmed
The ob mouse has morbid obesity and disordered breathing that is homologous to breathing of obese humans . - pubmed
Whole body plethysmography showed that PnO neostigmine depressed breathing ( P & lt ; 0.001 ) in B6 and ob mice and caused greater respiratory depression in B6 than ob mice ( P & lt ; 0.05 ) . - pubmed
OBJECTIVES : To examine pharmacotherapy for pain in a sample of 1,801 depressed older primary care patients . - pubmed
PARTICIPANTS : One thousand eight hundred one patients aged 60 and older who met diagnostic criteria for major depression or dysthymia . - pubmed
Oxcarbazepine ( Trileptal ) monotherapy dramatically improves quality of life in two patients with postherpetic neuralgia refractory to carbamazepine and gabapentin . - pubmed
We conducted an open - label pilot clinical trial to evaluate the safety and efficacy of adding oral azathioprine to the treatment regimen of 15 multiple sclerosis patients breaking through monotherapy with interferon beta-1b . - pubmed
Patients with recurrent hernias were excluded if the initial repair was from a preperitoneal approach . - pubmed
RESULTS : Recurrences occurred in five patients ( 0.47 % ) during a mean follow - up time of 23 months ( range : 2 - 47 ) . - pubmed
First autochthonous case of canine ocular onchocercosis in Germany . - pubmed
The current authors conducted a retrospective study of 61 patients with both emphysema of the upper zones and diffuse parenchymal lung disease with fibrosis of the lower zones of the lungs on chest computed tomography . - pubmed
Dyspnoea on exertion was present in all patients . - pubmed
Pulmonary hypertension was present in 47 % of patients at diagnosis , and 55 % during follow - up . - pubmed
The purpose of this work was to develop an abdominal aortic aneurysm ( AAA ) model that resembles human aneurysms with potential for further growth , patent collateral vessels , and a predictable tendency to rupture , and that can be used in the development of new endoprostheses and implant training . - pubmed
OBJECTIVE : The objective of this study was to establish the non - inferiority of an oral enzyme therapy ( Phlogenzym-(PE ) ) as compared to the non - steroidal anti - inflammatory drug ( NSAID ) diclofenac ( DC ) in patients with osteoarthritis ( OA ) of the hip . - pubmed
METHODS : Ninety patients presenting with painful episodes of OA of the hip were treated for 6 weeks in one study centre in a phase III , randomised , double blind , parallel group trial . - pubmed
For 71.1 % of the PE patients and for 61.4 % of the DC patients rates of good or very good global investigator assessments of efficacy were calculated ( test of non - inferiority : p = 0.0011 ) . - pubmed
PE may well be recommended for the treatment of patients with osteoarthritis of the hip with signs of inflammation as indicated by a high pain level . - pubmed
Feasibility of percutaneous nephrolithotomy under assisted local anaesthesia : a prospective study on selected patients with upper urinary tract obstruction . - pubmed
METHODS : Twenty - four patients with unilateral renal obstruction due to pelvic stones & gt ; or = 2.0 cm were enrolled in our study . - pubmed
OBJECTIVE : To evaluate the safety and efficacy of vertebroplasty and kyphoplasty using the data presented in published clinical studies , with respect to patient pain relief , restoration of mobility and vertebral body height , complication rate , and incidence of new adjacent vertebral fractures . - pubmed
Apoptosis , programmed cell death , is a physiological phenomenon , necessary for normal function of every organism . - pubmed
OBJECTIVE : Imaging systems for patients with cleft palate typically are not portable , but are essential to obtain an audiovisual record of nasoendoscopy and otoscopy procedures . - pubmed
Effect of oxygen on health quality of life in patients with chronic obstructive pulmonary disease with transient exertional hypoxemia . - pubmed
RATIONALE : Ambulatory oxygen improves acute exercise performance in people with chronic obstructive pulmonary disease ( COPD ) . - pubmed
OBJECTIVES : We undertook a series of individual randomized controlled trials ( N - of-1 RCTs ) to measure the effect of oxygen in patients with COPD who do not meet criteria for mortality reduction with long - term oxygen therapy . - pubmed
CONCLUSIONS : This study does not support the general application of long - term ambulatory oxygen therapy for patients with COPD who do not meet criteria for mortality reduction with long - term oxygen therapy . - pubmed
Two weeks later the patient underwent right parathyroidectomy that proved to be a parathyroid adenoma . - pubmed
This case should alert physicians to the association of multiple brown tumors in PHPT and that the presentation may be an aggressive one mimicking metastasis , patients with osteoporosis warrant at least calcium profile to rule out a secondary cause . - pubmed
Prevalence of central nervous system cryptococcosis in human immunodeficiency virus reactive hospitalized patients . - pubmed
A retrospective study was conducted on a total of 1,863 HIV reactive hospitalized patients suspected of cryptococcal meningitis . - pubmed
Prevalence of cryptococcal meningitis in the total HIV reactive cohort was 2.09 % . - pubmed
We therefore studied the spectrum and outcome of PHT in children ( & lt;or=14 years of age ) over a period of 9 years . - pubmed
CONCLUSIONS : EHPVO and cirrhosis are the two major causes of PHT in children . - pubmed
CT measurement of trunk muscle areas in patients with chronic low back pain . - pubmed
MATERIALS AND METHODS : In this study , we evaluated 36 patients with chronic low back pain and 34 healthy volunteers . - pubmed
Comparative evaluation of the effects of statins on human stem and cancer cells in vitro . - pubmed
Anticancer effects of statins were studied using karyotypically normal human embryonic stem cells ( hESC ) ( HES3 ) , karyotypically abnormal hESC ( BG0IV ) , embryonal carcinoma ( NTERA-2 ) , ovarian ( TOV-112D ) and colorectal cancer ( HT-29 ) cells . - pubmed
Oral polio vaccine ( OPV ) has been used safely and efficiently for more than 40 years in preventive medicine . - pubmed
Immunodeficient recipients of OPV can excrete poliovirus vaccine strains for a long period and are at risk of developing flaccid paralysis . - pubmed
Histopathological analysis of infected mouse lung tissues demonstrated severe alveolitis , hemorrhaging , and spread of the virus throughout the entire lung . - pubmed
Primary outcome measures were deltamethrin residue and bioassay performance ( 60 minute knock - down and 24 hour mortality after a three minute exposure ) using a strain of Anopheles gambiae s.s . - pubmed
Participants were assessed at the beginning of the longitudinal study and on average two years later by means of the California Verbal Learning Test ( CVLT ) and the Consortium to Establish a Registry for Alzheimer ' s Disease - Neuropsychological Assessment Battery ( CERAD - NAB ) , a multidimensional cognitive test battery . - pubmed
pyogenes is a strictly human pathogen ( with the exception of a single strain ) , the value of all animal models is limited . - pubmed
Phage - resistance linked to cell heterogeneity in the commercial strain Lactobacillus delbrueckii subsp . - pubmed
The aim of this work was to study the relationship between the cell morphological heterogeneity and the phage - resistance in the commercial strain Lactobacillus delbrueckii subsp . - pubmed
A 1 - year - old boy presented with the clinical manifestation of intractable complex partial seizures and development delay ; physical examination revealed two fibrotic scars and alopecia . - pubmed
This study was done to evaluate left ventricular dimensions , systolic function , and the left ventricular myocardial performance index in children with obesity . - pubmed
MEHTODS AND RESULTS : Thirty - three obese children whose mean age was 9.8 + /- 2.4 years , weight was 61.3 + /- 20.8 kg , body mass index was 29.5 + /- 5.8 kg / m(2 ) , and percentage of actual weight to ideal body weight for height ( % IBW ) was 170 + /- 25 % , underwent echocardiography for the assessment of left ventricular dimensions , and systolic and global functions . - pubmed
There were 2 , 14 , and 17 children with mild ( & lt ; 140 % IBW ) , moderate ( 141 - 160 % IBW ) , and severe obesity ( & gt ; 160 % IBW ) , respectively . - pubmed
All were within the normal range , with the exception of two children ( 6 % ) who had mild left ventricular dilatation . - pubmed
CONCLUSION : The left ventricular dimensions and systolic function in children with obesity were essentially normal . - pubmed
The left ventricular myocardial performance index , which is an indicator for left ventricular global function , was found to be abnormal in 33 % of the children , and may be used for the early detection of left ventricular global dysfunction . - pubmed
A Gram - negative , non - spore - forming , cream - coloured bacterial strain , UM2 ( T ) , was isolated from an open hexachlorocyclohexane ( HCH ) dump site at Ummari village in Lucknow , India . - pubmed
The type strain is UM2 ( T ) (= MTCC 9473(T ) = CCM 7545(T ) ) . - pubmed
METHODS : The study group consisted of 24 postmenopausal women ( mean age , 59.7 y ) who had various diseases , excluding rheumatoid arthritis , and had been treated with 10 mg or more of oral glucocorticoids ( prednisolone equivalent ) per day for more than 6 mo . - pubmed
The chick embryo fibroblast infected by Rous sarcoma virus in vitro acquires the capacity to produce the acid mucopolysaccharides which are found in the tumors caused by this virus and which are also produced by tumor cells in vitro . - pubmed
Clinic - epidemiological evaluation of ulcers in patients with leprosy sequelae and the effect of low level laser therapy on wound healing : a randomized clinical trial . - pubmed
The study objectives were to analyze the clinic - epidemiological characteristics of patients attended at one specialized dressing service from a leprosy - endemic region of the Brazilian Amazon and to evaluate the effect of low level laser therapy ( LLLT ) on wound healing of these patients . - pubmed
METHODS : Clinic - epidemiological evaluation of patients with leprosy sequelae was performed at the reference unit in sanitary dermatology of the state of Para in Brazil . - pubmed
Fifty - one patients with ulcers related to leprosy were evaluated , twenty - five of them were randomly assigned to a low level laser therapy group or a control group . - pubmed
CONCLUSIONS : Ulcers in patients with leprosy remain a major source of economic and social losses , even many years after they have been cured of M. - pubmed
The purpose of this study was to confirm this with a larger sample size and to establish whether raised IMT in black stroke - free individuals is associated with increased carotid plaque . - pubmed
UNLABELLED : In a study of 2005 institutionalized older people , use of oral bisphosphonates was associated with a 27 % reduction in risk of death compared to non - users after adjusting for potential confounders . - pubmed
METHODS : Two thousand and five institutionalized older people ( mean age 85.7 years ) were assessed at baseline and followed up for hip fracture and death for at least 5 years . - pubmed
A prospective study of macular thickness in amblyopic children with unilateral high myopia . - pubmed
PURPOSE : To compare macular thickness of the normal fellow eye to that of the amblyopic eye using optical coherence tomography ( OCT ) in children with unilateral high myopia . - pubmed
CONCLUSIONS : Amblyopic children with unilateral high myopia tend to have a thicker fovea and thinner inner and outer macula in the amblyopic eye compared to the normal fellow eye . - pubmed
The findings indicate that anatomic changes may be present in the retinas of amblyopic children with unilateral high myopia . - pubmed
Another possible limitation is that the ARCC trial included patients with advanced renal cell carcinoma , and thus it can not be conclusively determined how our findings would apply to patients with less advanced disease . - pubmed
Amitriptyline and prochlorperazine inhibit proinflammatory mediator release from human mast cells : possible relevance to chronic fatigue syndrome . - pubmed
MATERIAL AND METHODS : This study involved 40 pregnant women ; normal ( n = 20 ) , and PE ( n = 20 ) , the latter of who were classified into ( i ) mild ( n = 10 ) and severe PE ( n = 10 ) ; ( ii ) PE with SGA ( n = 7 ) and without SGA ( n = 13 ) . - pubmed
Four weeks after surgery , new scar formation or progression of the preoperative scar at the site of access were seen in 14 of 29 ( 48.3 % ) patients who were treated with one - stage dilation whereas only 2 of 19 ( 11.0 % ) patients who were treated with gradual dilation developed new scarring at the access site ( P=0.007 ) . - pubmed
This study aimed at investigating the survival rate and prognostic factors of laryngeal carcinoma patients in the absence of the use of laryngectomy , radiotherapy , and chemotherapy . - pubmed
In laryngeal carcinoma patients with no surgery , radiotherapy or chemotherapy , the factors affecting the survival rates include primary site , pathological grade , T - stage , N - stage , and clinical stage , and of them , T - stage and N - stage are the independent prognostic factors . - pubmed
We show that : ( 1 ) the sequence variant spectrum of these two individuals ' DNA sequences is largely comparable to existing non - supercentenarian genomes ; ( 2 ) the two individuals do not appear to carry most of the well - established human longevity enabling variants already reported in the literature ; ( 3 ) they have a comparable number of known disease - associated variants relative to most human genomes sequenced to - date ; ( 4 ) approximately 1 % of the variants these individuals possess are novel and may point to new genes involved in exceptional longevity ; and ( 5 ) both individuals are enriched for coding variants near longevity - associated variants that we discovered through a large genome - wide association study . - pubmed
PATIENTS AND METHODS : The study involved 592 children with radiographically confirmed CAP whose respiratory secretion samples were tested using the Luminex xTAG Respiratory Virus Panel Fast assay , which simultaneously detects influenza A virus , influenza B virus , respiratory syncytial virus ( RSV)-A and -B , parainfluenzavirus-1 , -2 , -3 , and -4 , adenovirus , human metapneumovirus , coronaviruses 229E , NL63 , OC43 , and HKU1 , enterovirus / rhinovirus , and bocavirus . - pubmed
RESULTS : A total of 435 children ( 73 5 % ) were positive for at least one virus : the most frequently detected was RSV , which was found in 188 ( 31 7 % ) , followed by rhinovirus ( n = 144 , 24 3 % ) , bocavirus ( n = 60 , 10 1 % ) , influenza viruses ( n = 57 , 9 6 ) , and hMPV ( n = 49 , 8 2 % ) . - pubmed
CONCLUSIONS : The findings of this study highlight the importance of respiratory viruses ( mainly RSV and rhinovirus ) in children with CAP and show the characteristics of both the single infections and co - infections associated with the disease . - pubmed
The saponin of red ginseng protects the cardiac myocytes against ischemic injury in vitro and in vivo . - pubmed
Adult rat heart ischemia , which was induced by ligation of the left anterior descending coronary artery , was employed for the in vivo analysis . - pubmed
Transcatheter closure of perimembranous ventricular septal defects : initial human experience with the Amplatzer membranous VSD occluder 2 . - pubmed
Anxiety , depression , and pain in burning mouth syndrome : first chicken or egg ? - pubmed
OBJECTIVE : The aim of this study was to evaluate the relationship between pain , depression , and anxiety in BMS and healthy patients in order to hypothesize a possible underlying pathogenetic model . - pubmed
METHODS : Fifty - three patients with BMS and 51 healthy volunteers matched for sex and age were enrolled . - pubmed
RESULTS : BMS patients and healthy volunteers showed a statistically significant difference in psychiatric features : Regression analysis showed that pain is affected by depression ( R = 0.373 ; R(2 ) corrected = 0.123 ; F = 8.563 ; P & lt ; .005 ) , and depression is affected by anxiety ( R = 0.512 ; R(2 ) corrected = 0.248 ; F = 18.519 ; P & lt ; .001 ) . - pubmed
CONCLUSIONS : We may hypothesize that anxiety could determine a secondary demoralization in BMS patients ( depression ) and depressive symptoms could contribute to pain , accordingly . - pubmed
BACKGROUND : An inherited basis for congenital extrahepatic portosystemic shunts ( EHPSS ) has been demonstrated in several small dog breeds . - pubmed
RESULTS : Data of 135 client owned dogs diagnosed with EHPSS at the Faculty of Veterinary Medicine of Utrecht University from 2001 - 2010 were retrospectively analyzed . - pubmed
CONCLUSION : The remarkable similarity of phenotypic variation in many dog breeds may indicate common underlying genes responsible for EHPSS across breeds . - pubmed
Since there are similarities between the pathogenesis of preeclampsia and atherosclerosis we hypothesised an increased accumulation of oxLDL at the materno - foetal and foeto - foetal interface within the placental tissue of preeclamptic women compared to women with normotensive pregnancies ( controls ) . - pubmed
Histopathological features of bisphosphonate - associated osteonecrosis : findings in patients treated with partial mandibulectomies . - pubmed
The present study investigated the histopathologic and radiographic features of stage 3 bisphosphonate - associated osteonecrosis of the jaw ( BAONJ ) in patients who were treated with partial mandibulectomies . - pubmed
Bisphosphonates had been orally administered to 10 patients with osteoporosis and intravenously administered to 1 patient with metastatic carcinoma . - pubmed
On radiographic images , massive osteolysis and periosteal bone formations were conspicuous , and a thin mandibular cortical width was observed in 5 of 10 osteoporosis patients despite the previous use of bisphosphonate . - pubmed
Evaluation of the pathogenesis of meningitis caused by Streptococcus suis sequence type 7 using the infection of BV2 microglial cells . - pubmed
Streptococcus suis is an important agent of swine and human meningitis . - pubmed
METHODOLOGY : The clinical data of 65 adult patients with CCs at the Second Affiliated Hospital of Chongqing Medical University between 2007 and 2011 were analyzed retrospectively . - pubmed
Forty - six patients underwent extrahepatic bile duct ( EHBD ) dilatation resection plus Roux - en - Y hepaticojejunostomy ( HJ ) , 16 patients underwent partial hepatectomy plus EHBD resection plus Roux - en - Y HJ , 1 patient underwent partial hepatectomy , 1 patient underwent external drainage only , and 1 patient underwent reconstruction of hepatoenteric anastomosis by excision of stenosis . - pubmed
An 83 - year - old man suddenly developed numbness in his bilateral perioral area and right hand . - pubmed
The patient was diagnosed as having cheiro - oral syndrome with bilateral perioral sensory disturbance , probably due to unilateral pontine tegmental hemorrhage . - pubmed
In this report we use both an established neuronal cell line model and an embryonic stem cell - based system to examine human neuronal innate immunity and responses to neurotropic alphavirus infection in cultured cells . - pubmed
Two - legged hopping in place in sync with an auditory cue ( 2.3 , 3.0 Hz ) was studied in a group of six individuals with expressive language impaired ASD ( ELI - ASD ) and an age - matched control group . - pubmed
A strain of Gram - staining - negative , aerobic , non - flagellated , non - gliding and rod - shaped bacteria , designated WS - MY3 ( T ) , was isolated from a brown algae reservoir in South Korea . - pubmed
The major polar lipids of strain WS - MY3(T ) were phosphatidylethanolamine and two unidentified lipids . - pubmed
The DNA G+C content of strain WS - MY3(T ) was 37.3 mol% and its DNA - DNA relatedness values with F. - pubmed
The type strain is WS - MY3(T ) ( = KCTC 32328(T ) = CECT 8286(T ) ) . - pubmed
The 3 - D morphological features extracted from breast MRI were used to analyze the malignant likelihood of tumor from ninety - five solid breast masses ( 44 benign and 51 malignant ) of 82 patients . - pubmed
Behavioural sleep problems in children with attention - deficit / hyperactivity disorder ( ADHD ): protocol for a prospective cohort study . - pubmed
INTRODUCTION : Children with attention - deficit / hyperactivity disorder ( ADHD ) commonly experience behavioural sleep problems , yet these difficulties are not routinely assessed and managed in this group . - pubmed
Intermedin in the paraventricular nucleus attenuates cardiac sympathetic afferent reflex in chronic heart failure rats . - pubmed
Cardiac sympathetic afferent reflex ( CSAR ) is enhanced in chronic heart failure ( CHF ) rats . - pubmed
The aim of this study is to determine the effect of IMD in the PVN on CSAR and its related mechanisms in CHF rats . - pubmed
METHODOLOGY / PRINCIPAL FINDINGS : Rats were subjected to left descending coronary artery ligation to induce CHF or sham - operation ( Sham ) . - pubmed
Schistosomes are parasitic worms that can survive in the hostile environment of the human bloodstream where they appear refractory to both immune elimination and thrombus formation . - pubmed
By degrading host inflammatory signals like ATP , and pro - thrombotic signals like ADP , these parasite enzymes may minimize host immune responses , inhibit blood coagulation and promote schistosome survival . - pubmed
INTRODUCTION AND OBJECTIVES : There have been no studies conducted in the past that focus on the significance of congestive heart failure in patients with prosthetic valve endocarditis . - pubmed
We studied the incidence of congestive heart failure in patients with prosthetic valve endocarditis and analyzed its profile . - pubmed
In this study , we addressed the prognostic significance of heart failure in patients with prosthetic valve endocarditis and analyzed its outcome based on chosen therapeutic strategies . - pubmed
We compared the profiles of patients with prosthetic valve endocarditis based on the presence of heart failure , and performed a multivariate logistic regression model to establish the prognostic significance of heart failure in patients with prosthetic valve endocarditis and identified the prognostic factors of in - hospital mortality in these patients . - pubmed
RESULTS : Persistent infection ( odds ratio=3.6 ; 95 % confidence interval , 1.9 - 6.9 ) and heart failure ( odds ratio=3 ; 95 % confidence interval , 1.5 - 5.8 ) are the strongest predictive factors of in - hospital mortality in patients with prosthetic valve endocarditis . - pubmed
Patients indicated for MACI in this follow - up were 13 to 65 years of age , although they were excluded if they had a BMI & gt;35 kg / m(2 ) , had undergone prior extensive meniscectomy , or had ongoing progressive inflammatory arthritis . - pubmed
METHODS : Male Wistar streptozotocin - diabetic rats ( and age - matched controls ) were examined 2 ( early ) and 8 weeks ( late ) after the induction of diabetes . - pubmed
Anthrax is a non - contagious infectious disease ; it primarily affects herbivores , but all mammals , including humans , can be affected . - pubmed
Humans may contract anthrax directly or indirectly from infected animals . - pubmed
Veterinary surveillance systems , providing information about animal and human cases , should increase the efficacy of the animal anthrax management in order to protect population . - pubmed
In this paper we propose a new , detailed classification of anthrax outbreaks , based on the source of the infection and the risk level for humans . - pubmed
They were divided into three groups , Group I ( control ) from healthy children ( n = 6 ) , Group II from acyanotic CHD children ( n = 12 ) and Group III from cyanotic CHD children ( n = 12 ) . - pubmed
METHODS : A cohort of 208 patients cumulatively treated between June 2008 and December 2012 qualified for study inclusion , each undergoing total - gland cryoablation for prostate cancer . - pubmed
CONCLUSIONS : Saturated prostate cryoablation by reducing APVC would be beneficial for cancer control without compromising patient safety . - pubmed
A partial resolution of AP could manifest as complex human diseases , and the inability to resolve AP may play a role in speciation . - pubmed
Predictive factors for occult contralateral carcinoma in patients with unilateral papillary thyroid microcarcinoma by preoperative ultrasonographic and pathological features . - pubmed
BACKGROUND : The surgical extent and indication for treatment in patients with papillary thyroid microcarcinoma ( PTMC ) remain a controversial issue . - pubmed
The aim of this study was to investigate the predictive factor for contralateral occult carcinoma in patients with unilateral PTMC by preoperative ultrasonographic and pathological features . - pubmed
METHODS : Of the total patients who underwent thyroidectomy , 455 patients with PTMC confined to one unilateral lobe as diagnosed using preoperative ultrasonography ( US ) were enrolled in the study . - pubmed
All patients underwent preoperative US review to investigate the US features of PTMC such as laterality , location , size , internal component , echogenicity , margin , calcification shape , multifocality , bilaterality , extrathyroidal extension , and location with respect to the trachea . - pubmed
RESULTS : Of the total of 455 patients who underwent total thyroidectomy for preoperatively detected unilateral PTMC , 71 patients ( 15.6 % ) had contralateral occult carcinoma . - pubmed
Clinicopathological characteristics did not significantly differ between patients with and without contralateral occult carcinoma . - pubmed
Multivariate analysis showed that the absence of a well - defined margin and the presence of a probably benign nodule in the contralateral lobe were independent predictive factors for contralateral occult carcinoma in patients with unilateral PTMC in preoperative US images . - pubmed
CONCLUSION : We demonstrated that an absence of a well - defined margin and the presence of a probably benign nodule in the contralateral lobe were independent predictive factors for contralateral occult carcinoma in patients with unilateral PTMC in preoperative US . - pubmed
Usefulness and safety of endoscopic retrograde cholangiopancreatography in children with pancreaticobiliary maljunction . - pubmed
BACKGROUND : To assess the diagnostic ability and safety of endoscopic retrograde cholangiopancreatography ( ERCP ) in in - depth preoperative examination of children patients with pancreaticobiliary maljunction ( PBM ) . - pubmed
METHODS : In 63 patients with a definite diagnosis of PBM , the ability to visualize the bile and main pancreatic ducts was compared between ERCP , which was performed in 63 patients with a definite diagnosis of PBM , and magnetic resonance cholangiopancreatography ( MRCP ) , which was performed before ERCP in 29 patients . - pubmed
As complications , hyperamylasemia developed in 12 patients ( 19 % ) , but no other severe complications such as pancreatitis were observed . - pubmed
CONCLUSIONS : ERCP as part of an in - depth preoperative examination of children with PBM is useful and safe . - pubmed
Tuberculosis should be suspected in patients presenting with multiple bone lesions , especially in endemic areas . - pubmed
CONCLUSION : Neutrophil to lymphocyte ratio value may be used as a novel marker that is easily administered in patients with nasal polyps and obtained with low - cost tests . - pubmed
OBJECTIVE : More than 85 % of patients with end - stage renal disease start dialysis through a tunneled dialysis catheter ( TDC ) for long periods while their arteriovenous fistula or vascular access graft ( arteriovenous graft [ AVG ] ) matures . - pubmed
Because TDCs are associated with a high risk of complications , including death and infection , use of an AVG that can be cannulated safely immediately after implantation may reduce morbidity in these patients by allowing earlier TDC removal . - pubmed
OBJECTIVE : To evaluate the correlation between diaphragm thickness assessed by ultrasound ( US ) with respiratory function tests and the diaphragm motor responses , in patients with amyotrophic lateral sclerosis ( ALS ) . - pubmed
METHODS : 42 consecutive ALS patients were studied ( 11 with bulbar - onset ) , excluding patients with marked orofacial paresis . - pubmed
MATERIALS AND METHODS : Thirty - five patients with degenerated spondylolisthesis , discogenic pain , and kyphoscoliosis were examined . - pubmed
CONCLUSION : The eFACE is a reliable , reproducible , and straightforward digital clinical measure with which to assess facial function and disfigurement in patients with facial paralysis . - pubmed
We enrolled 36 patients with severe sepsis . - pubmed
Other perfusion variables failed to predict vasopressor requirement in patients with severe sepsis . - pubmed
The aim of this study was to assess the status of the iliopsoas muscle and other flexors and extensors of the hip in long - term follow - up with magnetic resonance imaging after complete iliopsoas tenotomy in patients with unilateral DDH treated with open reduction with a medial approach . - pubmed
METHODS : The study included 20 patients who underwent open reduction with a medial approach for unilateral DDH and had long - term follow - up . - pubmed
hydroxy , epoxy and dihydroxy FA in obese subjects with persistent low - grade inflammation . - pubmed
We aimed to evaluate levels of inflammatory markers and blood oxylipins in obese subjects before and after weight reduction . - pubmed
Interestingly , in subjects with low- grade inflammation several AA - derived oxylipins ( 5 - , 8 - , 12 - hydroxyeicosatetraenoic acids ( HETE ) ) were significantly higher compared to subjects with no inflammation before weight reduction and significantly reduced after weight reduction . - pubmed
Comment on " Exposure - response modeling of non - cancer effects in humans exposed to Libby Amphibole Asbestos ; update " by Benson et al . - pubmed
Given the dismal outcome of our case and previously reported cases , we propagate the implementation of targeted therapies to newly diagnosed patients with acute myeloid leukemia t(2;3 ) . - pubmed
Here , we show that TLT develops as newly formed lymphoid tissue in the colon following dextran sulphate sodium induced colitis in C57BL / 6 mice , where it can be distinguished from the preexisting colonic patches and solitary intestinal lymphoid tissue . - pubmed
METHODS : A total of 336 patients with heart valve disease were included in this study , including 167 with AF and 169 with sinus rhythm . - pubmed
AIMS / HYPOTHESIS : Women with a history of gestational diabetes mellitus ( GDM ) have raised liver triacylglycerol . - pubmed
The aim of this work was to examine liver triacylglycerol accumulation in women with GDM and the effect of modest energy restriction . - pubmed
METHODS : Sixteen women with GDM followed a 4 week diet ( 5 MJ [ 1200 kcal]/day ) . - pubmed
Twenty - six women who underwent standard antenatal care for GDM ( matched for age , BMI , parity and ethnicity ) were used as a comparator group . - pubmed
RESULTS : Fourteen women , who completed the study , achieved a weight loss of 1.6 + - 1.7 kg over the 4 week dietary period . - pubmed
CONCLUSIONS / INTERPRETATION : Liver triacylglycerol in women with GDM was not elevated , unlike observations in non - pregnant women with a history of GDM . - pubmed
A Canola Oil - Supplemented Diet Prevents Type I Diabetes - Caused Lipotoxicity and Renal Dysfunction in a Rat Model . - pubmed
We investigated the effect of a canola oil - supplemented diet on the metabolic state and diabetic renal function of a type I diabetes experimental model . - pubmed
Male Sprague - Dawley rats were randomly divided into four groups : ( 1 ) normoglycemic+chow diet , ( 2 ) normoglycemic+a canola oil - supplemented chow diet , ( 3 ) diabetic+chow diet , and ( 4 ) diabetic+a canola oil - supplemented chow diet . - pubmed
Diabetic rats fed with a canola oil - supplemented diet had higher body weights , were less hyperphagic , and their mesenteric , retroperitoneal , and epididymal fat pads weighed more than diabetic rats on an unsupplemented diet . - pubmed
Xylose - assimilating pathway was constructed in a d - lactic acid producing Pediococcus acidilactici strain and evolutionary adapted to yield a co - fermentation strain P. - pubmed
Efficacy In Vitro of Caffeine and Valproic Acid on Patient - Derived Undifferentiated Pleomorphic Sarcoma and Rhabdomyosarcoma Cell Lines . - pubmed
We subsequently established patient - derived cell lines from undifferentiated pleomorphic sarcoma ( UPS ) and rhabdomyosarcoma ( RMS ) , both of which are recalcitrant cancers . - pubmed
MATERIALS AND METHODS : In the present study , we tested CAF and VPA and their combination on the two patient - derived sarcoma cell lines . - pubmed
Tumour mutation status and sites of metastasis in patients with cutaneous melanoma . - pubmed
METHODS : Prospective cohort of patients with a histologically confirmed primary cutaneous melanoma at three tertiary referral centres in Melbourne , Australia from 2010 to 2015 . - pubmed
RESULTS : Of 1048 patients , 306 ( 29 % ) developed metastasis over a median 4.7 year follow - up period . - pubmed
Overall , 113 serum samples were also collected from the dogs living in these areas ; suspecting to be risk factors for this infection . - pubmed
Infection rate was significantly more in cows with the history of abortion . - pubmed
CONCLUSION : The results show a high seroprevalence of the infection and possibly the role of the dogs in horizontal transmission of the infection . - pubmed
To the best of the authors ' knowledge , the case presented is the first report of ACC in a patient with CDRIE due to infection of pacemaker leads . - pubmed
The wearable cardioverter defibrillator ( WCD ) is a temporary treatment option for patients with potentially reversible risk of sudden cardiac death . - pubmed
In most but not all pregnant patients presenting with a new or worsening neurological abnormality , the risks intrinsic to the disease will outweigh the risks of imaging . - pubmed
Systolic time ratio measured by impedance cardiography accurately screens left ventricular diastolic dysfunction in patients with arterial hypertension . - pubmed
The IMPEDDANS study aims to assess the usefulness of ICG for the screening of left ventricular diastolic dysfunction ( LVDD ) in patients with HT . - pubmed
Methods : Patients with HT were assessed by echocardiography and ICG . - pubmed
Conclusion : The ICG derived value of STR allows the accurate screening of LVDD in patients with HT . - pubmed
However , the progression - free survival and overall survival in patients with GA is less than in patients with diffuse astrocytomas . - pubmed
Differences in the histological pattern , immunohistochemical and molecular - genetic profiles , survival of patients with GA and diffuse astrocytomas GII are shown there . - pubmed
A clinical case of a patient with transformation of a diffuse astrocytoma in GA ( GIII ) and then into a secondary glioblastoma is presented . - pubmed
Genome - wide association study and heritability estimate for ectopic ureters in Entlebucher mountain dogs . - pubmed
There was no single outstanding SNP associated with the phenotype , and the association signals were not close to known genes involved in human congenital anomalies of the kidney or lower urinary tract . - pubmed
Gender Identity and Sexual Function in 46,XX Patients with Congenital Adrenal Hyperplasia Raised as Males . - pubmed
In individuals with congenital adrenal hyperplasia ( CAH ) and 46,XX karyotype , androgens produced by the adrenal glands during the intrauterine development promote virilization of the genitals , which may even result in the development of a well - formed penis . - pubmed
Additional strategies may be necessary to improve survival among female cardiac arrest patients . - pubmed
INTRODUCTION : The aim of this systematic review is to investigate the effects of perioperative intravenous administration of MgSO4 on postoperative pain , analgesic consumption and adverse effects in patients undergoing orthopedic surgery . - pubmed
We evaluated clinical outcomes , comparing postoperative pain scores , cumulative analgesic consumption , time to first analgesia , and adverse effects between orthopedic surgery patients with and without the administration of MgSO4 . - pubmed
However , intravenous MgSO4 administration should be considered as a strategy to relieve postoperative pain in orthopedic surgery patients . - pubmed
Patients from the mini - AVR group reported less postoperative pain . - pubmed
In conclusion , a close cooperation between the various disciplines in the pre- and postoperative management is essential in order to optimize the timing and outcome of patients with UC . - pubmed
Humanized Mouse Model Mimicking Pathology of Human Tuberculosis for in vivo Evaluation of Drug Regimens . - pubmed
Although they were employed for analyzing tuberculosis ( TB ) disease , there is little data on the spatial organization and cellular composition of human immune cells in TB granuloma pathology in this model . - pubmed
We demonstrate that human immune system mice , generated by transplanted human fetal liver derived hematopoietic stem cells develop a continuum of pulmonary lesions upon Mycobacterium tuberculosis aerosol infection . - pubmed
We consider this model instrumental for deeper understanding of human specific features of TB pathogenesis and of particular value for the pre - clinical drug development pipeline . - pubmed
Suspected citrus leprosis symptoms on leaves and fruits of sweet oranges ( Citrus sinensis ( L. ) Osb . ) - pubmed
To confirm the visual identification , leaves and fruits from Valencia sweet orange exhibiting typical lesions of leprosis were collected from several locations in the departments of Casanare ( Yopal , Aguazul ) and Meta ( Guamal , Villavicencio , and Cumaral ) . - pubmed
These several lines of evidence confirmed that the symptoms observed in sweet oranges at Meta and Casanare are due to the infection by CiLV - C . To our knowledge , this is the first report of this virus in Colombia . - pubmed
Molecular analysis of clonally related Salmonella Typhi recovered from epidemiologically unrelated cases of typhoid fever , Brazil . - pubmed
This study demonstrates that propiconazole can induce hypopigmentation in zebrafish , disrupt mitochondrial bioenergetics , and can alter locomotor activity . - pubmed
BACKGROUND : Lymphopenia has been observed in severe pandemic influenza A / H1N1 in developed countries . - pubmed
This study aimed to observe change of lymphocyte counts in patients with severe pandemic influenza A / H1N1 and to investigate the correlation of lymphopenia and severe pandemic influenza A / H1N1 . - pubmed
CONCLUSIONS : Lymphopenia along with other clinical parameters may be helpful in early differential diagnosis of severe pandemic influenza A / H1N1 . - pubmed
In this study , we showed that miR-103 was deregulated in osteoarthritis patients . - pubmed
Regulation of miR-103 expression in human chondrocytes may be an effective treatment for osteoarthritis . - pubmed
Effects of polyploidy on the coordination of gene expression between organellar and nuclear genomes in Leucanthemum Mill . - pubmed
Mesenchymal stem cell - derived exosomes ameliorate erection by reducing oxidative stress damage of corpus cavernosum in a rat model of artery injury . - pubmed
With similar potency compared with the stem cell therapy and other unique advantages , IC injection of MSC- Exos could be an effective treatment to ameliorate erectile function in a rat model of arterial injury . - pubmed
BACKGROUND : Inadvertent perioperative hypothermia is common in patients undergoing off - pump coronary artery bypass grafting ( OPCAB ) . - pubmed
Patients were divided into 4 groups based on body temperature at the time of intensive care unit admission after surgery ( moderate - to - severe hypothermia , < 35.5 C ; mild hypothermia , 35.5 C-36.5 C ; normothermia , 36.5 C-37.5 C ; and hyperthermia , > = 37.5 C ) . - pubmed
Patients who were hypothermic at postoperative intensive care unit admission but attained normothermia thereafter were at a lower risk of all - cause mortality compared to patients who did not regain normothermia ( adjusted hazard ratio , 0.631 ; 95 % confidence interval , 0.453 - 0.878 ) , while they were still at a higher risk of all - cause mortality than those who were consistently normothermic ( adjusted hazard ratio , 1.435 ; 95 % confidence interval , 1.090 - 1.890 ) . - pubmed
Cell - free DNA ( cfDNA ) and nucleosomes are two biomarkers of cell death and neutrophil extracellular trap formation that are increased in dogs with sepsis , immune - mediated haemolytic anaemia , cancer and following trauma and have diagnostic and prognostic values . - pubmed
Following this , the cytotoxicity of these compounds was evaluated against four cancer cell lines ( human hepatoma cell HepG-2 , human lung cancer cell A549 , human breast cancer cell MCF-7 , and human colon cancer cell HCT-116 ) and one normal cell line ( human gastric epithelial cell line - GES - 1 ) . - pubmed
We hope this exoskeleton device can help stroke patients with loss of function in the upper extremities to resume motor activities in order to maintain activities of daily living . - pubmed
Previous in vitro studies showed that EVs purified from normal mouse AML12 hepatocytes ( " EVNorm " ) attenuate the pro - fibrogenic activities of activated hepatic stellate cells ( HSCs ) , a principal fibrosis - producing cell type in the liver . - pubmed
RNA sequencing ( RNA - seq ) revealed that EVNorm therapy of mice receiving CCl4 for 5 weeks resulted in significant differences [ false discovery rate ( FDR ) & lt;0.05 ] in expression of 233 CCl4 - regulated hepatic genes and these were principally associated with fibrosis , cell cycle , cell division , signal transduction , extracellular matrix ( ECM ) , heat shock , cytochromes , drug detoxification , adaptive immunity , and membrane trafficking . - pubmed
These findings show that EVs from human or mouse hepatocytes regulate toxin - associated gene expression leading to therapeutic outcomes including suppression of fibrogenesis , hepatocyte damage , and/or inflammation . - pubmed
Multidrug - Resistant ( MDR ) and Extensively Drug Resistant ( XDR ) Acinetobacter baumannii ( Ab ) represent a serious cause of healthcare - associated infections worldwide . - pubmed
Two sets of trials , one with 12 early - to - intermediate maturing and the other with 13 intermediate - to - late maturing hybrids , improved for tolerance to multiple stresses common in farmers ' fields in eastern Africa ( drought , northern corn leaf blight , gray leaf spot , common rust , maize streak virus ) , were evaluated on - farm under smallholder farmers ' conditions in a total of 42 and 40 environments ( site - year - management combinations ) , respectively , across Kenya , Uganda , Tanzania and Rwanda in 2016 and 2017 . - pubmed
In this study , we aimed to describe in detail respiratory tract complications as the most prominent clinical feature among agammaglobulinemic patients . - pubmed
Bronchiectasis was found in 13 patients undergoing HRCT ( 44.8 % ) . - pubmed
In patients with IRIDA , the iron uptake in the intestine is remarkably reduced , and iron deficiency anemia ( IDA ) develops . - pubmed
Cutibacterium acnes and autoinflammatory bone disease : Case series of three patients . - pubmed
Multimodal MALDI Imaging Mass Spectrometry Reveals Spatially Correlated Lipid and Protein Changes in Mouse Heart with Acute Myocardial Infarction . - pubmed
In this work , we demonstrate an application of multimodal chemical imag - ing using matrix - assisted laser desorption / ionization mass spectrometry ( MALDI - MS ) which provided comprehensive molecu - lar information in situ within the same mouse heart tissue sections with myocardial infarction . - pubmed
This methodology allowed us to interpret the lipid and protein molecular pathology of the very same infarcted region in a mouse model of myocardial infarction . - pubmed
RESULTS : Among 105 patients , 14 ( 13.3 % ) developed ORN . - pubmed
The SUVmax of the periodontal region in patients with ORN ( 3.35 + - 1.23 ) was significantly higher than patients without ORN ( 1.92 + - 0.66 ) ( P < .01 ) . - pubmed
The corresponding CT stage of periodontitis in patients with ORN was significantly higher ( 2.71 + -0.47 ) than patients without ORN ( 1.80 + -0.73 ) ( P < .01 ) . - pubmed
MATERIALS AND METHODS : We performed retrospective CGM and blood tests on 189 outpatients with impaired glucose tolerance ( n = 22 ) , type 1 diabetes mellitus ( T1DM , n = 67 ) , or type 2 diabetes mellitus ( T2DM , n = 100 ) . - pubmed
New approaches to complement vaccination are needed to combat the spread of SARS - CoV-2 and stop COVID-19 related deaths and long - term medical complications . - pubmed
First study of safety and tolerability of 3,4 - methylenedioxymethamphetamine - assisted psychotherapy in patients with alcohol use disorder . - pubmed
BACKGROUND : 3,4 - methylenedioxymethamphetamine ( MDMA ) therapy has qualities that make it potentially well suited for patients with addictions , but this has never been explored in a research study . - pubmed
This is the first MDMA addiction study , an open - label safety and tolerability proof - of - concept study investigating the potential role for MDMA therapy in treating patients with alcohol use disorder ( AUD ) . - pubmed
AIMS : This study aimed to assess if MDMA - assisted psychotherapy can be delivered safely and can be tolerated by patients with AUD post detoxification . - pubmed
METHODS : Fourteen patients with AUD completed a community alcohol detoxification and received an eight - week course of recovery - based therapy . - pubmed
Describe the incidence of invasive pneumococcal disease ( IPD ) in serotypes with reduced antibiotic sensitivity to penicillin ( RAS - Pen ) in adults over 59 years of age and its association with childhood anti - pneumococcal vaccination coverage ( CVC ) and community consumption of beta - lactam . - pubmed
The non - PCV13 strains that increased the most at the end of the period were 6C , 11A and 15A. - pubmed
The incidence of IPD due to PCV13 with RAS - Pen at > 59 years was decreasing and was associated with CVC . - pubmed
Impact of 6- versus 12 - month dual antiplatelet therapy on clinical prognosis in patients with high bleeding risk : Insights from the 4 - year results of the I LOVE IT 2 study . - pubmed
BACKGROUND : The optimal DAPT duration after percutaneous coronary intervention ( PCI ) in HBR patients is unclear . - pubmed
Prevalence and prognosis of HBR patients were explored , and clinical outcomes of HBR patients who underwent 6- versus 12 - month DAPT were compared . - pubmed
HBR patients were associated with a higher risk of BARC type 3 or 5 bleeding ( 2.95 vs. 1.52 % , p = .03 ) , NACE ( 31.82 vs. 25.99 % , p = .01 ) , all - cause death ( 5.68 vs. 3.13 % , p = .008 ) and stroke ( 9.09 vs. 3.83 % , p < .001 ) than non - HBR patients at 4 years . - pubmed
There were no significant differences in BARC type 3 or 5 bleeding ( 3.07 vs. 2.76 % , p = 1.00 ) or NACE rate ( 31.9 vs. 33.8 % , p = .72 ) between patients who underwent 6- and 12 - month DAPT . - pubmed
CONCLUSIONS : HBR patients are at a higher risk of long - term bleeding and ischemic events than non - HBR patients . - pubmed
Four patients ( 4.7 % ) developed late complications ( Port site hernia 2 ; internal hernia 1 ; Stomal ulcer 1 ) . - pubmed
The mean BMI pre - RYGB was 46.6 + - 5.9 kg / m2 , and the mean % EBWL ( percent excess body weight lost ) of the patients at 12 and 24 months post - revision were 56.2 % and 64.3 % , respectively . - pubmed
Effects on cancer patients of leukapheresis with the continuous - flow blood cell separator . - pubmed
The immunologic effects of leukapheresis on cancer patients and three other groups of donors using the continuous - flow blood cell separator are presented according to the protocol described in the preceding article . - pubmed
Transient declines were noted in per cent T - lymphocytes of some , but not all , leukapheresed normal donors and cancer patients . - pubmed
There were no changes in lymphocyte - mediated cytotoxicity to a melanoma cell line in 2 of 4 melanoma patients , while values in 2 patients fell by about one - half within 4 hours and returned to preleukapheresis levels by 24 hours . - pubmed
Oestrogen treatment of male rats causes " feminization " of the hepatic androstenedione metabolism . - pubmed
The patient had lymphangioma of the orbit which evidently had bled secondary to increased venous pressure and injection of contrast bolus . - pubmed
Both of the 2 patients with transient visual disturbances had diabetic retinopathy . - pubmed
A large number of oxanilic acid esters and N - heteroaryl oxamic acid esters were prepared and found to have antiallergic activity using the rat passive cutaneous anaphylaxis ( PCA ) test . - pubmed
Prevalence of dental caries and enamel defects in the primary dentition of Antiguan pre - school children aged 3 - 4 years including an assessment of their habits . - pubmed
The sulfate concentration determined by the proposed method in human blood serum ( n = 6 in each instance ) was 35.4 - 43.3 micrograms ml-1 in normal persons , 50.3 - 62.5 micrograms ml-1 in jaundice patients and 83.3 - 155.6 micrograms ml-1 in diabetic patients . - pubmed
An important question is how to use such substances in an effective , directed way to reduce cancer risk in humans . - pubmed
However , CO2ER in experimental animals tended to decrease 12 hours after brain injury and was not significantly different from that in controls . - pubmed
Evaluation of Mycobacterium leprae particle agglutination test , using eluates of filter paper blood spots . - pubmed
Attention is drawn to the existence of this rare form of aphasia and to the lack of appropriate educational facilities for aphasic children in general . - pubmed
Fistulotomy , coupled with insertion of stents , was successful in seven of eight patients and was associated with relief of jaundice . - pubmed
Thirty - one patients with advanced carcinoma of the pancreas and with no prior exposure to chemotherapy were treated with HCFU . - pubmed
Hepatobiliary injury associated with experimental small - bowel bacterial overgrowth in rats . - pubmed
[ Anisotropy and reentrant ventricular tachycardia : experimental model in the isolated rabbit heart ] . - pubmed
The purpose of this study was to study the role of anisotropic distribution of conduction velocity in the initiation and perpetuation of ventricular tachycardia in an experimental model of sustained reentrant ventricular tachycardia in the Langendorff perfused rabbit heart . - pubmed
Metabolic changes in man under hypokinesia and physical exercise . - pubmed
It was theorized that physical exercise may be used to prevent the development of metabolic changes in man under hypokinesia ( diminished muscular activity ) . - pubmed
In this investigation we assessed the efficacy of physical exercise in attenuating metabolic disturbances in twelve physically healthy men aged 19 to 23 years under 100 days of hypokinesia and 15 days of a readaptation period . - pubmed
It was concluded that hypokinesia caused marked debilitating metabolic changes in man . - pubmed
We measured local cerebral metabolic rate for glucose ( ICMRGIc ) using positron emission tomography ( PET ) in six children with Sturge - Weber syndrome ( SWS ) and in six neurologically asymptomatic children with facial capillary hemangioma suggestive of SWS . - pubmed
Children with advanced SWS showed markedly depressed ICMRGIc in the anatomically affected cerebral hemisphere in a distribution that extended beyond the abnormalities depicted on computed tomography scan . - pubmed
In two infants with SWS and recent seizure onset , interictal PET revealed a paradoxical pattern of increased ICMRGIc in the cerebral cortex of the anatomically affected hemisphere . - pubmed
Subsequent PET ( 28 months later ) in this child revealed the typical ICMRGIc pattern seen in advanced SWS . - pubmed
In neurologically asymptomatic children with the facial stigmata of SWS and in children with early SWS , PET provides a sensitive measure of the extent and degree of cerebral metabolic impairment . - pubmed
Serial PET studies in children with SWS can be used to assess disease progression and , together with computed tomography or magnetic resonance imaging , may be useful in the selection of suitable candidates for cerebral hemispherectomy or focal cortical resection . - pubmed
We report data on 43 patients with polyarteritis affecting the kidneys . - pubmed
The majority ( 41 patients ) had renal histological evidence of microscopic polyarteritis . - pubmed
These results suggest that our approach to treatment should be modified towards lessening immunosuppression in older patients and in patients with renal failure at diagnosis . - pubmed
Forearm and finger hemodynamics , blood pressure control , and lipid changes in diabetic hypertensive patients treated with atenolol and prazosin . - pubmed
Antihypertensive medications that reduce blood pressure and improve peripheral perfusion would have advantages in diabetic hypertensive patients . - pubmed
In a randomized , two - placebo - period , single - blind , two - way , crossover study , finger and forearm blood flow , lipid levels , and blood pressure control were determined in 19 diabetic hypertensive patients given prazosin and atenolol , with each drug and placebo period lasting four weeks . - pubmed
In conclusion , prazosin demonstrated a potentially more appropriate hemodynamic profile than atenolol in diabetic hypertensive patients in this study . - pubmed
Only a few yeast strains did not display any killer activity against the aerobic actinomycetes studied , thus confirming that the killer phenomenon is widespread among microorganisms . - pubmed
We report the details of a young woman in whom pericardial tamponade developed acutely following preparation for allogeneic bone marrow transplantation for acute lymphoblastic leukaemia . - pubmed
The application of digital coronary arteriography in the evaluation of patients with known or suspected coronary artery disease is considered . - pubmed
The use of an intraoral mental nerve block greatly decreases the pain for the patient . - pubmed
A rapid automatic method for determining shock sensitivities of mice . - pubmed
Strains of Streptomyces tenebrarius and biosynthesis of nebramycin . - pubmed
The surgical specimens from three resected giant - cell carcinomas are described and the subsequent courses of the patients are summarized . - pubmed
Despite the aggressive behaviour of this type of cancer , patients may survive for many years if the tumour is resected . - pubmed
The interaction of metoclopramide and two dopaminergic agonists , dopamine and apomorphine , was investigated on ganglionic transmission at the superior cervical ganglion of the anaesthetized cat . - pubmed
An abnormal tryptophan metabolism is present in patients affected by Erithematodes with high excretion particularly of kynurenines and xanthurenic acid . - pubmed
Both patients initially developed clinical symptoms of multiple sclerosis : visual disturbances , intention tremor , reduced abdominal reflexes , impaired coordination and difficulties with walking . - pubmed
After the exposure to methanol had ceased the multiple sclerosis symptoms persisted in patient 1 but disappeared gradually in patient 2 ( patient 2 had a history of excessive alcohol consumption , which is a critical fact in this discussion ) . - pubmed
Ultimately autopsies confirmed this picture : histological examination of patient 1 revealed plaques in the spinal cord , in the stem and in the proximity of the lower horn of one lateral ventricle , whereas no localized demyelination could be found in patient 2 . - pubmed
An acute interstitial nephritis was found in a patient with sudden renal failure and lung infection caused by Legionella pneumophilia . - pubmed
Quantitative changes in the state of the nucleolar apparatus of endothelial cells in the rabbit jugular veins were studied at regeneration after trauma produced either at 8 - 10 a.m. or at 8 - 10 p.m. - pubmed
Green turtle fibropapillomatosis : challenges to assessing the role of environmental cofactors . - pubmed
Green turtle fibropapillomatosis ( GTFP ) is a growing threat to the survival of green turtle ( Chelonia mydas ) populations worldwide . - pubmed
HF neck suction induced a 0.20 - Hz component in all 16 control subjects and none of the 26 transplant subjects . - pubmed
Intravenous cholangiography detected common bile duct ( CBD ) stones in 10 patients , of whom only five had a dilated CBD ( & gt ; 8 mm ) . - pubmed
Tritrichomonas foetus is a protozoan parasite associated with reproductive failure in the bovine . - pubmed
As a result there have been only two cases of bovine trichomoniasis in the UK over the past 20 years . - pubmed
METHODS : Wistar rats were sensitised with a suspension of heat killed Mycobacterium tuberculosis in oil in the scruff of the neck and challenged intra - articularly with stress protein or M tuberculosis preparations . - pubmed
Gossypol inhibits basal and estrogen - stimulated DNA synthesis in human breast carcinoma cells . - pubmed
Estrogen stimulates the growth of hormone - dependent human breast cancer . - pubmed
GP at 10.0 and 20.0 microM inhibited both basal and E2 - stimulated DNA synthesis in human breast cancer cells . - pubmed
Prevalence of aortic valve stenosis in patients affected by gastrointestinal angiodysplasia . - pubmed
The aim of this study was to examine the prevalence of aortic valve stenosis in patients with gastrointestinal angiodysplasia . - pubmed
METHODS : We studied retrospectively 83 patients submitted to gastrointestinal endoscopy and found affected by angiodysplasia . - pubmed
Although no murmurs were present in 15 patients ( 25 % ) , some echocardiographic abnormalities such as aortic leaflet sclerosis , mitral annular calcification , their association , or trivial mitral regurgitation detectable only at PW - Doppler were found . - pubmed
Abnormal hemostatic profiles indicating hemorrhagic tendency have been reported in rodents exposed to prolonged fluctuation in ambient temperature , known as SART ( specific alternation of rhythm in temperature)-stressed animals . - pubmed
We observed large peripheral tears of the retinal pigment epithelium in two patients , a 59 - year - old man and a 15 - year - old girl , who had acute retinal necrosis . - pubmed
Both patients had curled folds of tissue at the posterior edge of the retinal pigment epithelial tear . - pubmed
Effective chemotherapy of tuberculosis requires rapid assessment of drug sensitivity because of the emergence of multidrug - resistant Mycobacterium tuberculosis . - pubmed
Signals could be detected within minutes after infection of virulent M. - pubmed
[ Arterial hypertension in patients with terminal kidney failure : pathogenetic variants and treatment principles ] . - pubmed
We isolated one clone from a human genomic phage library , which represents a partial ALD pseudogene , spanning exon 7 to exon 10 and exhibits approximately 93 % sequence homology with the ALD gene in this region . - pubmed
Lumbar , brain - stem , and cortical PTN SEPs were intraoperatively monitored in 7 patients undergoing repair of aortic coarctation under variable isoflurane concentration ( up to 1.2 % ) . - pubmed
PURPOSE : A 63 - year - old female with Fuchs ' endothelial corneal dystrophy , stromal edema and subepithelial scarring was inappropriately treated with phototherapeutic keratectomy , leading to a central focal circular corneal scar and decreased visual acuity that required penetrating keratoplasty . - pubmed
METHODS : From 1990 - 1995 , during the five year period , 44 ( 35.2 % ) of 125 patients with sarcoidosis at LAC + USC Medical Center had liver involvement . - pubmed
The outcome of patients who receive treatment remains similar , as far as liver function is concerned , suggesting that most of the patients with liver involvement undergo natural remission . - pubmed
Unless the patient has progressive liver dysfunction , it is advisable to monitor liver enzymes periodically and obtain liver biopsies only if clinically indicated . - pubmed
These include legal regulations , international guidelines for evaluating antiparasitic drugs , the refinement of animal models for parasitic infections , cryopreservation and cultivation of parasites in vitro or in chicken eggs , the maintenance of arthropods by artificial feeding , and the use of immunological and molecular in vitro techniques ( e.g. - pubmed
Efficacy and safety of loratadine plus pseudoephedrine in patients with seasonal allergic rhinitis and mild asthma . - pubmed
Although nasal obstruction may play an important role in modulating lower airway function , no prior trial has used a decongestant in combination with an antihistamine in patients with allergic rhinitis and concomitant asthma . - pubmed
OBJECTIVE : We sought to determine the efficacy and safety of loratadine ( 5 mg ) plus pseudoephedrine ( 120 mg ) ( L / P ) twice daily in patients with seasonal allergic rhinitis and mild asthma . - pubmed
METHODS : We conducted a randomized , double - blind , placebo - controlled trial of L / P in 193 subjects during the fall allergy season . - pubmed
RESULTS : Total rhinitis and asthma symptom severity scores were significantly reduced in patients receiving active therapy compared with those receiving placebo throughout the 6 - week study . - pubmed
These results were confirmed by comparing expression levels between normal and neoplastic human prostate tissues using Northern analysis . - pubmed
[ Intermittent antero - medial divisional block in patients with coronary disease ] . - pubmed
Intravenous infusion of PCA50941 ( 100 microg / min ) reversed the hemodynamic variables from the shock state to control values within 20 min in 5 of 6 animals , whereas i.v . - pubmed
administration of Bay K 8644 ( 10 - 30 microg / min ) was not effective in 4 of 5 animals , and the vehicle ( DMSO ) was not effective in none of 4 animals in reversing the hemodynamic shock state . - pubmed
Ammonium tetrathiomolybdate ( TTM ) is the treatment of choice for chronic Cu poisoning in sheep and is recommended in Wilson ' s disease . - pubmed
UNLABELLED : We evaluated the effect on the diagnostic yield of visceral arteriography in patients with acute gastrointestinal bleeding of a protocol requiring a positive 99mTc - red blood cell scintiscan before the performance of arteriography ( scintigraphic screening ) . - pubmed
CONCLUSION : Scintigraphic screening appears to increase by a factor of 2.4 the diagnostic yield of arteriography by screening out patients who are not actively bleeding at the time of the examination , thus sparing them the risks and costs of a nondiagnostic invasive study . - pubmed
The yeast strain complemented by At . - pubmed
OBJECTIVE : To assess in children with a transcranial Doppler the effect on cerebral blood flow velocities of desflurane , whose cerebral vasodilator effects have been studied in animals and in adults with intracranial lesions . - pubmed
In patients with diabetes mellitus optimal regulation of the blood glucose levels , with a view to preventing glycosuria , is a condition of speedy recovery . - pubmed
Successful triple - antibiotic therapy for cutaneous infection due to Mycobacterium chelonae . - pubmed
The patient was free of recurrence 3 years after follow up . - pubmed
PURPOSE : Gene modified autologous tumor cell vaccines have demonstrated a protective and therapeutic effect in murine tumor model systems . - pubmed
MATERIALS AND METHODS : We obtained 1 cm3 tumor tissue from 12 patients undergoing resection of primary or metastatic renal cell carcinoma . - pubmed
A retrospective evaluation of the relationship between serum bactericidal and inhibitory titres and treatment outcome in 195 adult Thai patients with severe melioidosis was conducted . - pubmed
This literature review demonstrates that hospitalised patients may not be receiving adequate pain relief due to health professionals ' belief that optimum doses of analgesia may affect patients ' respiratory capability . - pubmed
We have studied in vitro and in vivo activity of cyclosporin - A ( CSA ) on hematopoiesis in patients affected by hypoplastic MDS without blast excess . - pubmed
DESIGN AND METHODS : Nine consecutive patients with hypoplastic refractory anemia ( RA ) , followed up in our out - patient unit , were treated with CSA at daily doses of 1 - 3 mg / kg for at least three months . - pubmed
INTERPRETATION AND CONCLUSIONS : About one half of hypoplastic RA patients benefited from CSA treatment . - pubmed
Similar additive effects may be unexpectedly efficient and beneficial in humans after infections with persistent viruses such as hepatitis C virus and hepatitis B virus and possibly human immunodeficiency virus . - pubmed
It is possible that concurrent prescription of cytozar together with magnetization of blood in patients with hemoblastoses should permit enhancing the efficacy of treatment . - pubmed
Employment of weak magnetic fields is a satisfactory and worth - while therapeutic attempt to be made in a multimodality treatment of patients with hemoblastoses . - pubmed
Although the molecular mechanisms whereby this hormone modulates the sex ratio of malaria parasites remain to be elucidated , it probably activates , within the parasite , transduction pathways similar to those found in other eukaryotes . - pubmed
An osteochondral defect was created with a 5 - mm circular punch in the humeral articular surface of both glenohumeral joints of 32 adult White Leghorn chickens . - pubmed
Patients undergoing SATE for LGIB were clinically monitored for development of ischemic complications . - pubmed
Of 523 admissions for UGIB and LGIB , 35 patients ( 6.7 % ) underwent SATE as definitive therapy for control of gastrointestinal hemorrhage ( 25 UGIB and 10 LGIB ) . - pubmed
Initial control of bleeding was achieved in 23/25 UGIB and 10/10 LGIB patients . - pubmed
Rebleeding at less than 30 days occurred in 5/23 UGIB and 2/10 LGIB patients . - pubmed
SATE is an excellent therapeutic method for GI bleeding in selected patients , and definitive control is frequently afforded . - pubmed
However , by bypassing a urological evaluation the man might not learn the cause of infertility and not be offered specific corrective therapy . - pubmed
Of the remaining 6 patients 1 had testis cancer , 1 prostate cancer , 3 diabetes mellitus and 1 hypothyroidism . - pubmed
These transfectants were then analyzed for differences in metastasis formation in athymic mice . - pubmed
An 11 - year - old boy presented with fever , vomiting , rash , limping and blisters on his feet after a finger bite by his domestic rat . - pubmed
MATERIALS AND METHODS : The medical records of 22 patients with ATB were reviewed . - pubmed
RESULTS : Ten patients had biopsy - proven ATB , 11 had extra - abdominal TB with clinical suspicion of ATB and 1 had a positive trial of therapy . - pubmed
Vertebral compression and eosinophilia in a child with acute lymphatic leukemia . - pubmed
CONCLUSION : In patients with atopic asthma , changes in bronchial eosinophils and lung function during steroid therapy are closely related but do not occur simultaneously . - pubmed
Symptomatic diabetic and non - diabetic neuropathies in a series of 100 diabetic patients . - pubmed
We have reviewed the clinical and pathological data of a series of 100 consecutive diabetic patients with symptomatic neuropathy in order to learn more about the causes of neuropathy in this population and on the signs and symptoms that could suggest another cause than diabetes in this setting . - pubmed
Diabetes accounted for 74 % of the neuropathies in the whole group of patients and for 79 % of those with a fiber length dependent pattern of neuropathy . - pubmed
One third of patients had a neuropathy unrelated to diabetes . - pubmed
As a group , 71 % of the patients presented either a length dependent diabetic polyneuropathy ( LDDP ) or a proximal diabetic neuropathy ( PDN ) . - pubmed
Conversely , most patients with proximal diabetic neuropathy had usual features . - pubmed
Chronic inflammatory demyelinating neuropathy that was diagnosed in 9 % of the patients was the most common non - diabetic cause of neuropathy in this population . - pubmed
PURPOSE : Patients who have extensive stricture disease , those in whom hypospadias repair fails and those who sustain significant urethral trauma pose a reconstructive challenge for genitourinary surgeons . - pubmed
Unfortunately , one - third of patients have metastatic disease at the time of diagnosis and approximately 50 % of the patients undergoing surgical resection for less advanced disease eventually relapse . - pubmed
A combined impact of spinal deformity and impaired blood flow in the segmental arteries at the level of lesion on the severity of neurological disorders and on deterioration of life quality in patients with spinal inflammatory diseases has been found . - pubmed
Nosocomial infections among HIV - positive and HIV - negative patients in a Brazilian infectious diseases unit . - pubmed
This study compared the incidence of NI among HIV - positive and HIV - negative inpatients . - pubmed
METHODS : Patients from an infectious diseases ward who were classified as positive and negative regarding their HIV status were followed - up for 21 months in a prospective cohort study . - pubmed
Overall , HIV - positive patients were more likely to have a BSI than were HIV - negative patients ( P = .005 ) . - pubmed
CONCLUSIONS : In this study the HIV - positive patients were more likely to have NI than were the HIV - negative patients . - pubmed
Overall , HIV - positive patients are at increased risk for an NI caused either by S aureus or a BSI . - pubmed
The authors studied homeostasis in 182 patients , including 126 patients with exudative pleuritis of tuberculous etiology and 56 with parapneumonic pleuritis . - pubmed
Impaired responsiveness in patients with exudative pleuritis substantially affected the efficiency of etiotropic treatment . - pubmed
At the end of the basic course of therapy , the rate of marked residual pleural changes was 84.6 % in patients with tuberculous pleuritis ( Subgroup 1 ) . - pubmed
Greenberg ( Greenberg 1997 ) observed that a single session of right prefrontal cortex stimulation produced a significant decrease in compulsive urges in OCD patients lasting over eight hours . - pubmed
[ Does cortisone influence experimental cutaneous tuberculosis in the rat ] . - pubmed
Bilateral ablation of dorsolateral frontal cortex in the newborn animal failed to produce the frontal lobe syndrome typical of the adolescent and adult stages . - pubmed
At this time , no significant differences between normal animals and animals with prefrontal lesions were found . - pubmed
[ Is there another toxin produced by the disintegration of dead tissues in cases of gas gangrene caused by W. - pubmed
DIAGNOSIS OF CORNEAL DISEASE IN CHILDREN . - pubmed
Influence of warm ischemia injury on hepatic functional status and survival of liver graft in rats . - pubmed
OBJECTIVE : To investigate the changing patterns of functional and histological status , observe the posttransplantation survival of liver graft under different warm ischemia time ( WIT ) in rats , and determine the maximum limitation of liver graft to warm ischemia . - pubmed
CONCLUSIONS : These results indicate that rat liver graft could be safely subject to warm ischemia within 30 minutes . - pubmed
OBJECTIVE : We sought to determine whether reducing treatment frequency and UVA dose affects the therapeutic efficacy of oral PUVA for patients with chronic plaque psoriasis . - pubmed
According to our experience of over 100 hindlimb transplantations , in rats , catching the posterior wall with an anterior wall suture is the most common cause of thrombosis and acute transplant failure . - pubmed
RESULTS : Transplanted human peripheral lymphocytes survived and expressed EGFP in the mice over the 6- to 8 - week posttransplant period without any signs of graft - vs - host disease . - pubmed
MATERIALS AND METHODS : Orthotopic PC3 prostate tumours were established in male severe combined - immunodeficient mice ; on day 3 the mice were randomly assigned to one of four groups : paclitaxel 10 mg / kg intraperitoneally once a week ; STI571 50 mg / kg once a day for 6/7 weekdays ; combined paclitaxel and STI571 ; and vehicle - treated controls . - pubmed
METHOD : Forty - six tuberculosis patients were enrolled in the study . - pubmed
RESULTS : Atrial fibrillations occurred in 43,674 ( 14.9 % ) DM patients vs. 57,077 ( 10.3 % ) in the control group ( p<0.0001 ) . - pubmed
Spinal cord stimulation for critical leg ischemia : a review of effectiveness and optimal patient selection . - pubmed
Patients suffering from inoperable critical leg ischemia ( CLI ) ultimately face a major amputation . - pubmed
Subjecting these ZAG deficient animals to standard or lipid rich food regimens led to increased body weight in comparison to identically treated wild - type mice . - pubmed
A 32 - year - old woman was treated with long - term voriconazole therapy for recurrent aspergillosis associated with chronic granulomatous disease . - pubmed
The photosensitivity reaction resolved after the patient changed therapy to posaconazole . - pubmed
The S - ECC group contained 98 children with more than 5 decayed teeth , and the control group contained 94 caries - free children . - pubmed
DESIGN AND METHODS : In the present retrospective analysis , patients with high - grade non - Hodgkin ' s lymphoma with past history of tuberculosis and have had adequate antitubercular therapy were identified from a Lymphoma Group study . - pubmed
RESULTS : A cohort of eight patients with past history of tuberculosis was selected from 141 patients of high - grade non - Hodgkin ' s lymphoma . - pubmed
None of these patients developed reactivation of tuberculosis . - pubmed
Invasive pneumococcal disease in older children and adults declined markedly after introduction in 2000 of the pneumococcal conjugate vaccine for young children . - pubmed
Prehospital analgesia with acupressure at the Baihui and Hegu points in patients with radial fractures : a prospective , randomized , double - blind trial . - pubmed
As acupressure has been deemed effective for pain management by the National Institutes of Health , we conducted a study to evaluate its effectiveness in prehospital patients with isolated distal radial fracture . - pubmed
At the hospital , patients in the true - points group had significantly lower pain ( 36.6 + /- 11.0 vs 56.0 + /- 13.3 VAS score , P & lt ; .001 ) and anxiety scores ( 34.9 + /- 22.2 vs 53.4 + /- 19.7 VAS score , P = .022 ) . - pubmed
CONCLUSION : Acupressure in the prehospital setting effectively reduces pain and anxiety in patients with distal radial trauma . - pubmed
CASE PRESENTATION : We present a case of a young male who was transferred to our hospital because of shock and multiple organ failure after a complicated pericardial biopsy . - pubmed
During emergency surgery that followed , the patient died because of uncontrolled hemorrhage . - pubmed
CONCLUSION : This case highlights the difficulties both in early diagnosis and in the management of patients with cardiac angiosarcoma . - pubmed
In a previous study , it was demonstrated in human neuroblastoma SH - SY5Y cells that enhanced oxidative stress was related to METH - induced apoptosis . - pubmed
To determine if loss of cytoskeletal tension following stress deprivation decreases the mechanoresponsiveness of tendon cells , we cultured rat tail tendons under stress - deprived conditions for 48 hours and then cyclically loaded them for 24 hours at 1 % , 3 % , or 6 % strain at 0.17 Hz . - pubmed
Contrast - enhanced CT evaluation of clinically and mammographically occult multiple breast tumors in women with unilateral early breast cancer . - pubmed
If the aetiology of trigeminal neuralgia ( TN ) and other typical neuralgias must be brought back to the peripheral injury , their pathogenesis could involve central allodynic mechanisms , which , in patients with inter - critical pain , also engage the nociceptive neurons at the thalamic - cortical level . - pubmed
Sarcoptic mange in wild raccoon dogs ( Nyctereutes procyonoides ) in Korea . - pubmed
Purification and characterization of a new platelet aggregation inhibitor with dissociative effect on ADP - induced platelet aggregation , from the venom of Protobothrops elegans ( Sakishima - habu ) . - pubmed
METHODS : Eighteen SNPs in three genes , representing optimal haplotype - tagging sets , were genotyped in 355 COPD patients and 195 healthy smokers . - pubmed
We performed a retrospective study of all patients admitted to a Level 1 trauma center with isolated gunshot injury to the head during 6 1/2 years . - pubmed
Seventy - two patients with isolated gunshot wounds to the head were admitted . - pubmed
Recently , our group has evaluated the effect of various HN - derivatives on the 3 - quinuclidinyl benzilate ( QNB)-induced impairment of spatial orientation and memory in rats , by employing the T - maze test . - pubmed
This study examined general deficits in positive stimuli evaluation in adults with Attention Deficit Hyperactivity Disorder ( ADHD ) . - pubmed
We investigated the event - related potentials to positive , negative and neutral pictures in 32 adults with ADHD and 32 control subjects . - pubmed
We found significantly reduced EPN values for the ADHD patients compared to the healthy controls , but only in the positive stimuli condition , without any significant differences in the negative stimuli condition . - pubmed
MATERIALS AND METHODS : Seventeen women ( mean age 48.5 years ) with uterine cervical cancer received conventional magnetic resonance imaging ( MRI ) and DWI prior to chemoradiation and after 1 and 2 months of therapy . - pubmed
Water and solute transport through different types of pores in peritoneal membrane in CAPD patients with ultrafiltration failure . - pubmed
Disease - modifying therapy is ineffective in disabled patients ( Expanded Disability Status Scale [ EDSS ] & gt ; 6.5 ) with secondary progressive multiple sclerosis ( MS ) without relapses , or in primary progressive MS . - pubmed
To observe use of disease - modifying therapies in patients with progressive multiple sclerosis and EDSS & gt ; 6.5 . - pubmed
The plant extract Isatis tinctoria L. extract ( ITE ) inhibits allergen - induced airway inflammation and hyperreactivity in mice . - pubmed
Antioxidant nutrient intakes and corresponding biomarkers associated with the risk of atopic dermatitis in young children . - pubmed
BACKGROUND / OBJECTIVES : To investigate the association of antioxidant nutritional status with the risk of atopic dermatitis ( AD ) in young children in a case - control , population - based study . - pubmed
Final analysis included 180 AD ( mean age 5.3+/-0.9 years ) and 242 non - AD ( mean age 5.2+/-1.0 years ) children . - pubmed
Human conventional renal cell carcinoma ( CRCC ) remains resistant to therapy . - pubmed
Introduction of portable computed tomography scanners , in the treatment of acute stroke patients via telemedicine in remote communities . - pubmed
BACKGROUND : Thrombolysis is an established treatment in selected patients who present early to hospital after symptoms of acute ischaemic stroke . - pubmed
Treatment can only be offered after the patient has been assessed by highly trained physicians and imaging studies have ruled out a brain haemorrhage . - pubmed
METHODS : We report our preliminary experience with the portable computed tomography scanner in a remote community where Telemedicine was successfully used to evaluate and treat patients presenting with symptoms suggestive of an acute ischaemic stroke . - pubmed
All patients were evaluated remotely by a stroke neurologist in a TeleStroke service situated 207 km from the rural site . - pubmed
In three patients , thrombolysis was not offered because the computed tomography showed evidence of brain haemorrhage : two intracerebral haemorrhage and one subarachnoid haemorrhage . - pubmed
Repeat computed tomography scans showed a small haemorrhagic transformation in one patient . - pubmed
New imaging technologies have advanced our ability to treat lung cancers through enhanced and extended visualization of the tumor as well as patient and treatment response . - pubmed
Anti - oxidative effects of d - allose , a rare sugar , on ischemia - reperfusion damage following focal cerebral ischemia in rat . - pubmed
Rats were subjected to transient middle cerebral artery occlusion ( MCAO ) for 1 h under pentobarbital anesthesia . - pubmed
In another set of rats , apurnic / apyrimidic abasic sites ( AP - sites ) and 8 - hydroxy-2 '- deoxyguanosine ( 8 - OHdG ) , oxidative stress markers , were investigated 24 h after MCAO to examine the anti - oxidative effects of D - allose . - pubmed
The majority of prostanoid DP receptor - expressing cells in both rat and human asthmatic lungs are infiltrative macrophages and/or monocytes . - pubmed
Remission of endometriosis by hyperbaric oxygen treatment in rats . - pubmed
We designed this prospective , randomized controlled animal study to determine the effects of hyperbaric oxygen ( HBO ) on experimentally induced endometriosis in a rat model . - pubmed
Surgical induction of endometriosis was performed in 40 , nonpregnant , female , Wistar - Albino rats at the Experimental Medicine Research Center of Istanbul University ( DETAE ) . - pubmed
Hyperbaric oxygen treatment for 2 hours a day for 6 weeks resulted in significant remission of endometriosis in rats . - pubmed
Moreover , as several of the genes we studied have been linked to human gliomas , our results suggest that this linkage could reflect their organization into a conserved pathway for the control of glial cell proliferation . - pubmed
Peginterferon alpha and ribavirin combination therapy in patients with hepatitis C virus - related liver cirrhosis . - pubmed
BACKGROUND / AIMS : Pegylated interferon ( peginterferon ) and ribavirin combination therapy is less effective and associated with a higher frequency of serious complications in chronic hepatitis C patients with cirrhosis than in noncirrhotic patients . - pubmed
This study evaluated the efficacy and tolerability of peginterferon and ribavirin treatment in patients with hepatitis C virus ( HCV)-related cirrhosis . - pubmed
METHODS : Eighty - six patients with clinically diagnosed liver cirrhosis were treated with either peginterferon alpha-2a ( n=51 ) or peginterferon alpha-2b ( n=35 ) plus ribavirin . - pubmed
RESULTS : Of the 86 patients ( 55 males ) , 48 patients ( 55.8 % ) had HCV genotype 1 infection and 38 ( 44.2 % ) had genotype non-1 infection . - pubmed
CONCLUSIONS : Peginterferon and ribavirin combination therapy was relatively effective and feasible for clinically diagnosed HCV patients , especially in those with genotype non-1 infection and low baseline viral load . - pubmed
Exercise training attenuates acute hyperalgesia in streptozotocin - induced diabetic female rats . - pubmed
OBJECTIVES : We investigated the effects of chronic ( eight weeks ) low - to moderate - intensity swimming training on thermal pain sensitivity in streptozotocin - induced diabetic female rats . - pubmed
One day after the last exercise protocol ( 60 min / day , five days / week for eight weeks ) in the trained groups or after water stress exposure ( ten min / twice a week ) in the sedentary groups , the rats were subjected to a hot plate test . - pubmed
RESULTS : After eight weeks of swimming training , streptozotocin - induced diabetic rats presented a significantly lower body mass ( trained : 219.5 + - 29 g , sedentary : 217.8 + - 23 g ) compared with the normoglycemic groups ( trained : 271 + - 24 g , sedentary : 275.7 + - 32 g ) . - pubmed
CONCLUSION : Low - to - moderate swimming training for a long duration reduces thermal hyperalgesia during a hot plate test in streptozotocin - induced diabetic female rats . - pubmed
Polysomnography in combination with a questionnaire ( the Sleep Disturbance Scale for Children ) was performed in 12 Dutch patients with Rett . - pubmed
In 8 children , central apneas were present during the day often with obstructive apneas at night . - pubmed
Significant respiratory complaints were present in 3 patients , all had obstructive sleep apnea syndrome . - pubmed
Of the 12 patients with Rett , 8 ( 67 % ) snored , and in 5 obstructive sleep apnea syndrome was present . - pubmed
A novel actinomycete , strain A4036(T ) , was isolated from a soil sample collected from the Jabi district in Abuja , Nigeria . - pubmed
The taxonomic position of strain A4036(T ) was established using a combination of genotypic and phenotypic analyses . - pubmed
The type strain is A4036(T ) (= DSM 45507(T ) = KCTC 19870(T ) ) . - pubmed
Disease phenotype in sheep after infection with cloned murine scrapie strains . - pubmed
Phenotypic characterization of scrapie strains in sheep can be attempted by histological , immunohistochemical and biochemical approaches , but it is widely considered that strain confirmation and characterization requires rodent bioassay . - pubmed
Examples of scrapie strains obtained from original sheep isolates by serial passage in mice include ME7 , 79A , 22A and 87V. - pubmed
It is mutated in approximately half of all human cancers , leading to aberrant cell growth . - pubmed
Taxol and taurine protect the renal tissue of rats after unilateral ureteral obstruction : a stereological survey . - pubmed
Compared with the untreated UUO animals , the volume of necrotic and fibrotic tissues decreased -53 % and -63 % in the UUO rats treated with Taxol and taurine , respectively ( p<0.01 ) . - pubmed
Reducing the fasting period reduced the body weight loss in both species , and mice on shorter fasts could be group - housed , as hunger - induced fighting was lessened . - pubmed
BACKGROUND : We have created a theoretical algorithm for venous thromboembolism prophylaxis after traumatic brain injury ( TBI ) known as the Parkland Protocol , which stratifies patients into low- , medium- , and high - risk categories for spontaneous progression of hemorrhage . - pubmed
At admission , all patients were preliminarily categorized per the Parkland Protocol as follows : low risk ( LR ) , patients meeting the modified Berne - Norwood criteria ; moderate risk ( MR ) , injuries larger than the modified Berne - Norwood criteria without requiring a neurosurgical procedure ; high risk ( HR ) , any patient with a craniotomy / monitor . - pubmed
RESULTS : A total of 245 patients with intracranial hemorrhage were enrolled during the 13 - month study period . - pubmed
Spontaneous worsening was seen in 7.4 % of LR patients at 24 hours after injury , and no LR patients progressed at 72 hours after injury . - pubmed
In patients initially classified as MR at admission ( n = 42 ) , progression was seen in 42.9 % , with 91.5 % of patients demonstrating stable computed tomographic head scans at 72 hours after injury . - pubmed
In patients initially classified as HR ( n = 67 ) , 64.2 % demonstrated spontaneous progression of their TBI patterns , with 10.5 % continuing to progress at 72 hours after injury . - pubmed
A comparison of survival and pathologic features of non - alcoholic steatohepatitis and hepatitis C virus patients with hepatocellular carcinoma . - pubmed
METHODS : Patients transplanted for HCV and NASH at our institution from January 2000 to April 2011 were analyzed . - pubmed
Patient demographics , disease free survival , explant liver characteristics and HCC features ( tumour number , cumulative tumour size , vascular invasion and differentiation ) were compared between HCV and NASH liver transplant recipients . - pubmed
RESULTS : A total of 102 patients with NASH and 283 patients with HCV were transplanted . - pubmed
The incidence of HCC in HCV transplant recipients was 22.6 % ( 64/283 ) . - pubmed
Patients with NASH - HCC were statistically older than HCV - HCC patients ( P & lt ; 0.001 ) . - pubmed
A significantly higher proportion of HCV - HCC patients had vascular invasion ( 23.4 % vs 6.4 % , P = 0.002 ) and poorly differentiated HCC ( 4.7 % vs 0 % , P & lt ; 0.001 ) compared to the NASH - HCC group . - pubmed
Is cerebral glucose metabolism affected by chemotherapy in patients with Hodgkin ' s lymphoma ? - pubmed
OBJECTIVE : The aim of the study was to investigate the effect of chemotherapy treatment with ABVD on brain glucose metabolism in patients with Hodgkin ' s disease ( HD ) . - pubmed
METHODS : A total of 49 patients ( 23 men , 26 women ; mean age 32 + -9 years ) diagnosed with HD were included in the study . - pubmed
CONCLUSION : Our results support the conclusion of a very limited impact of ABVD chemotherapy on brain metabolism in patients with HD . - pubmed
INTRODUCTION : Infection is one of the main causes of patient death and graft failure early after kidney transplantation . - pubmed
RESULTS : The total number of infections per patient per day was not significantly different in peritoneal vs. hemodialysis modality ( 0,029 + /- 0.019 to 0,029 + /- 0,031 , p = ns ) . - pubmed
PD should be the first choice for renal replacement therapy in patients with end stage renal disease . - pubmed
METHODS : This prospective cohort study included 78 nontreated patients with moyamoya disease . - pubmed
During follow - up periods , de novo silent microbleeds developed in 4 ( 6.9 % ) of 58 adult patients . - pubmed
Hemorrhagic stroke occurred in 4 patients ( 6.9 % ) , all of who had silent microbleeds on initial examination . - pubmed
CONCLUSIONS : Careful and long - term follow - up of silent microbleeds would be essential to improve their outcome in adult patients with moyamoya disease . - pubmed
Practical importance and modern methods of the evaluation of skin microcirculation during chronic lower limb ischemia in patients with peripheral arterial occlusive disease and/or diabetes . - pubmed
Skin ischemia is one of the crucial phenomena during chronic lower limb ischemia in patients with peripheral arterial occlusive disease and/or diabetes . - pubmed
However , risk stratification for development of ischemic ulceration and/or skin necrosis in those patients is not easy , mostly due to the complex structure of the dermal vascular bed and limited possibilities for studying the skin capillaries in everyday practice . - pubmed
Myeloid - derived suppressor cells have a central role in attenuated Listeria monocytogenes - based immunotherapy against metastatic breast cancer in young and old mice . - pubmed
BACKGROUND : Myeloid - derived suppressor cells ( MDSCs ) are present in large numbers in blood of mice and humans with cancer , and they strongly inhibit T - cell and natural killer ( NK ) cell responses , at young and old age . - pubmed
RESULTS : We found that Listeria(at)-infected MDSC , which delivered Listeria(at ) predominantly to the microenvironment of metastases and primary tumours , where they spread from MDSC into tumour cells ( infected tumour cells will ultimately become a target for Listeria - activated immune cells ) . - pubmed
CONCLUSIONS : Although preclinical studies show that immunotherapy is less effective at old than at young age , our study demonstrates that Listeria(at)-based immunotherapy can be equally effective against metastatic breast cancer at both young and old age by targeting MDSC . - pubmed
METHODS : Nine patients with focal lesions of the condylar articular cartilage were consecutively treated with arthroscopic PGA -HA - covered microfracture and bone marrow concentrate ( PGA -HA - CMBMC ) . - pubmed
In the search for the etiological agent of Kawasaki disease , we suggest that a viral infection with potential antigenic similarities to rabies virus should be entertained . - pubmed
This study was done to predict the outcome of trial of voiding without catheter ( TWOC ) in patients with AUR with intravesical prostatic protrusion ( IPP ) detected on transabdominal ultrasound . - pubmed
METHODS : Patients with a first episode of AUR secondary to benign prostatic hypertrophy were assessed with ultrasound following bladder catheterization . - pubmed
CONCLUSION : Intravesical prostatic protrusion is a useful predictor of success of TWOC in patients with AUR . - pubmed
METHODS : Patients diagnosed with nonmetastatic T3 + or N1 + esophageal adenocarcinoma ( ACA ) or squamous cell carcinoma ( SCC ) from 1995 to 2002 who underwent surgical resection within 6 months of diagnosis were studied . - pubmed
Mainly induced by the Enterovirus 71 and Coxsackievirus A 16 infections , the frequently occurred HFMD outbreaks have become a serious public health problem in Southeast Asia . - pubmed
Currently , only a few studies have investigated the human immunity to HFMD in China . - pubmed
The levels of EV71 and CA16 specific antibodies before , during and shortly after the 2008 large outbreak of HFMD were evaluated by the microneutralization test . - pubmed
Left ventricular diastolic dysfunction is not uncommon in patients with chronic renal failure , including those with preserved left ventricular systolic function . - pubmed
The purpose of this study was to determine the relationship between left ventricular diastolic dysfunction and incidence of post - operative pulmonary edema in renal transplantation recipients with preserved left ventricular systolic function . - pubmed
METHODS : Pre - operative left ventricular function and incidence of pulmonary edema were retrospectively studied in 209 patients who underwent living - donor renal transplantation between January 2010 and October 2012 . - pubmed
In this model , mice are fed with the copper chelator cuprizone which leads to oligodendrocyte apoptosis and subsequent microgliosis , astrocytosis , and demyelination . - pubmed
Expression was analyzed in tumors from 85 bladder cancer patients and compared to overall survival ( median follow - up of 5.1 years ) . - pubmed
Years ago , the main allergy - causing domestic animals were dogs and cats , although nowadays there is an increasing number of allergic diseases related to insects , rodents , amphibians , fish , and birds , among others . - pubmed
The main allergic symptoms related to exotic pets are the same as those described for dog and cat allergy : respiratory symptoms . - pubmed
Tumor specimens were collected from 33 consecutive patients . - pubmed
[ On the problem of the evaluation of conditioned reflex formation by means of an electroencephalographic method in children with epileptiform syndrome ] . - pubmed
MATERIALS AND METHODS : Wistar rats underwent 180 minutes of bilateral lower limb ischemia and 240 minutes of reperfusion . - pubmed
Neuroimaging has played a critical role in the management of patients with neurological disease , since the first ventriculogram was performed in 1918 by Walter Dandy ( Mezger et al . - pubmed
Over the last century , technology has evolved significantly , and within the last decade , the role of imaging in the management of patients with neuro - oncologic disease has shifted from a tool for gross identification of intracranial pathology , to an integral part of real - time neurological surgery . - pubmed
Current neurological imaging provides detailed information about anatomical structure , neurological function , and metabolic and metabolism - important characteristics that help clinicians and surgeons non - invasively manage patients with brain tumors . - pubmed
It is valuable to review the evolution of neurological imaging over the past several decades , focusing on its role in the management of patients with intracranial tumors . - pubmed
We thus suggest mechanisms that might ultimately allow for evidence based integration of imaging in the management of patients with neuro - oncologic disease . - pubmed
METHODS : We reviewed medical records of MESCC patients in our institute who had at least one progressive neurological symptom ( weakness , sensory changes , urinary retention , or nerve root pain ) , were diagnosed by magnetic resonance imaging ( MRI ) , and were treated with at least radiotherapy . - pubmed
CONCLUSIONS : Our findings suggest that normal walking status at the first physician visit and inclusion of weekends during the pretreatment periods were factors that resulted in treatment delays even for MESCC patients with emergency neurological symptoms . - pubmed
[ Moving activity and wakefulness - sleep cycle changes in a mouse MPTP model of Parkinson ' s disease ] . - pubmed
Finally , 2 '- HCA potently suppressed the growth of mouse xenografts representing human leukemia or skin cancer . - pubmed
The HBV genotypes / subgenotypes , serotypes , mixed infections , and S gene mutations of 172 Cuban HBsAg and HBV - DNA positive patients were determined by direct sequencing and phylogenetic analysis . - pubmed
This first genetic study of Cuban HBV viruses revealed only strains that were interspersed with strains from particularly Europe , America , and Asia . - pubmed
Home mechanical ventilation represents a valuable therapeutic option to improve alveolar ventilation in patients with chronic respiratory failure . - pubmed
The prognosis of patients with local appendiceal carcinoids is excellent . - pubmed
The present study reports the case of a 22 - year - old female patient that presented with recurrent right lower abdominal pain of a three - year duration . - pubmed
BACKGROUND : Bronchoscopic lung - volume reduction with the use of one - way endobronchial valves is a potential treatment for patients with severe emphysema . - pubmed
METHODS : We randomly assigned patients with severe emphysema and a confirmed absence of collateral ventilation to bronchoscopic endobronchial - valve treatment ( EBV group ) or to continued standard medical care ( control group ) . - pubmed
The Beneficial Effect of Beta - Blockers in Patients With Cirrhosis , Portal Hypertension and Ascites . - pubmed
BACKGROUND : Patients with cirrhosis and portal hypertensive complications have reduced survival . - pubmed
As such , it has been suggested that nonselective beta - blocker therapy in patients with advanced ascites is harmful . - pubmed
The aim of this study was , therefore , to determine the risk of mortality in patients with cirrhosis and ascites taking nonselective beta - blocker therapy for the prevention of variceal hemorrhage . - pubmed
MATERIALS AND METHODS : This study was a retrospective analysis of 2,419 patients with cirrhosis and portal hypertension admitted to Parkland Memorial Hospital ( a university - affiliated county teaching hospital ) from 2003 - 2010 . - pubmed
Patients were subdivided into those with varices only , ascites only and those with both varices and ascites . - pubmed
Beta - blocker use was also assessed in specific cohorts ; mortality was 21.1 % in patients with severe ascites with varices who were not taking beta - blockers compared with 8.9 % in patients who were taking beta - blockers ( P = 0.05 ) . - pubmed
Overall , fewer patients taking beta - blockers died compared with those not taking beta - blockers in patients with varices only ( 6.4 % versus 12.1 % ) and those with ascites with or without varices ( 6.6 % versus 18.1 % ) ( P & lt ; 0.001 ) . - pubmed
CONCLUSIONS : Mortality was lower in patients with cirrhosis and portal hypertension taking nonselective beta - blockers than in those not taking beta - blockers . - pubmed
The use of nonselective beta - blockers provided a significant survival benefit in patients with all grades of ascites , including those with severe ascites . - pubmed
This " primate - specific " pattern may be related to the human - specific hearing loss phenotypes of channelopathy disorders , including the SLC26A4 - related diseases Pendred syndrome / DFNB4 . - pubmed
Time course investigation of intervertebral disc degeneration in a rat - tail puncture model . - pubmed
SIGNIFICANCE : The degenerative changes observed in this rat - tail puncture model are similar to human disc degeneration and that this model may be valuable for elucidating the molecular mechanisms and pathways underlying disc degeneration . - pubmed
CONCLUSION : This prospective , multi - institutional registry will provide novel oncological and QoL outcomes on patients with sinonasal malignancy to inform management decisions and disease prognostication . - pubmed
Cerebral oximetry as a biomarker of postoperative delirium in cardiac surgery patients . - pubmed
MATERIALS AND METHODS : An observational study was conducted with 30 consecutive adults with delirium after cardiac surgery . - pubmed
RESULTS : All patients presented delirium at entry . - pubmed
The mean oximetry value decreased from 66.4 + -6.7 ( mean+-SD ) to 50.8 + -6.8 on the first day after delirium onset and increased in patients whose delirium resorbed over the 3 days . - pubmed
Clinicopathological features of histological transformation from extranodal marginal zone B - cell lymphoma of mucosa - associated lymphoid tissue to diffuse large B - cell lymphoma : an analysis of 467 patients . - pubmed
This study analysed incidence , patient outcome , immunophenotype and prognostic factors of histological transformation ( HT ) from extranodal marginal zone B - cell lymphoma of mucosa - associated lymphoid tissue ( MALT lymphoma ) to diffuse large B - cell lymphoma ( DLBCL ) in 467 patients ( median age , 61 years ) . - pubmed
A 47 - year - old woman developed a headache and tinnitus in her right ear followed by sudden - onset left hemiparesis . - pubmed
A dural arteriovenous fistula may be detected in patients with cerebral venous sinus thrombosis during the chronic phase . - pubmed
RESULTS : In the 23 PIL patients , diffusive large B cell lymphoma ( DLBCL ) and enteropathy - associated T cell lymphoma ( EATL ) were the primary histopathological types , accounting for 47.8 % and 43.4 % of the total patients , respectively . - pubmed
The aneurismal sign was found in 26.2 % ( 11/42 ) lesions , more commonly seen in the patients with DLBCL than in those with EATL ( chi2=8.101 , P=0.004 ) . - pubmed
OBJECTIVE : To assess the effect of neuroblastoma ( NB ) on the intestinal microbiome , metabolism , and inflammatory parameters in a murine model . - pubmed
Following 10 weeks of tumor growth , all animals were sacrificed to collect total white adipose tissue ( WAT ) . - pubmed
CONCLUSIONS : The present study provides a first glimpse that human NB in a murine model induces tumor cachexia associated with alterations in metabolic and inflammatory parameters , as well as changes in the intestinal microbiota . - pubmed
Since the intestinal microbiome is known to contribute to the host 's ability to harvest energy , a favorable modulation of the intestinal microbiome in tumor patients could potentially represent a novel therapeutic target to prevent tumor - associated cachexia . - pubmed
Effects of a non - thermal plasma needle device on HPV-16 positive cervical cancer cell viability in vitro . - pubmed
The current work reveals the effects of a non - thermal needle - shaped atmospheric - pressure plasma on the viability of an adherent human cervical carcinoma cell line containing a human papillomavirus type 16 ( HPV-16 ) provirus . - pubmed
These findings reveal possibilities for NTP treatment of HPV-16 infected cervical cancers and indicate the importance of NTP parameters to treatment outcome . - pubmed
Three of the six evaluated strains showed levels of degradation of 32 , 26 and 47 % ( Polyporus tricholoma , Cilindrobasidium laeve and Deconica citrispora , respectively ) after twelve days of cultivation in the presence of the xenobiotic . - pubmed
METHODS : The study included iNPH patients undergoing overnight monitoring of the pulsatile / static ICP in whom a biopsy was taken from the frontal cerebral cortex during placement of the ICP sensor . - pubmed
Reference ( Ref ) biopsies were sampled from 13 patients who underwent brain surgery for epilepsy , tumours or cerebral aneurysms . - pubmed
RESULTS : iNPH patients responding to surgery ( n = 44 ) had elevated pulsatile ICP , indicative of impaired intracranial compliance . - pubmed
CONCLUSIONS : Idiopathic normal pressure hydrocephalus patients responding to CSF diversion present with abnormal pulsatile ICP , indicative of impaired intracranial compliance . - pubmed
Treatment at high - volume facilities and academic centers is independently associated with improved survival in patients with locally advanced head and neck cancer . - pubmed
CONCLUSIONS : Patients with locally advanced head and neck squamous cell carcinoma who are undergoing curative radiotherapy at HVFs and academic centers appear to have improved survival . - pubmed
Mouse models were made out of a relapsed cervical cancer patient 's tumour sample for original and recurrent cervical cancer , and gene analysis in both tumours and exosomes in these mouse models were performed . - pubmed
A retrospective observational study based on usual clinical practice was conducted in patients attending the ED due to low back pain during a period of 24 months . - pubmed
A total of 732 patients who requested medical assessment due to back pain in the ED of our hospital were analyzed , 91 of whom were treated with tapentadol whereas 641 received another treatment . - pubmed
Patients who received tapentadol also had a better clinical evolution of pain compared to those who did not receive it ( P & lt ; 10 ) and to those who received tramadol ( P & lt ; 10).In this study in patients with back pain , tapentadol shows clear advantages over the other analgesics analyzed , in terms of pain control and less need for reassessments . - pubmed
Methods : In this cross - sectional case - control study , 77 eyes of 58 patients were divided into three groups : a first group ( n = 34 ) encompassed eyes with resolved DME ( R - DME ) , a second group ( n = 24 ) corresponded to diabetic eyes without DME ( no - DME ) , and a third group ( n = 19 ) comprised a control group of nondiabetic healthy eyes . - pubmed
VA was significantly correlated with EZ reflectivity in diabetic patients ( r2 = 0.57 ; P & lt ; 0.0001 ) . - pubmed
CASE PRESENTATION : A case of a 15 - year - old boy is reported who presented with severe systemic inflammation , perimyocarditis and cardiogenic shock , in whom EGPA was initially suspected and later diagnosed with autoimmune adrenalitis with PGA . - pubmed
BACKGROUND : Frequent blood glucose readings are the most cumbersome aspect of diabetes treatment for many patients . - pubmed
Inference of emergent cattle pastoralism in the southern Sahara desert based on localized hypoplasia of the primary canine . - pubmed
Here , we consider the effects of this dietary transition on early childhood health by examining localized hypoplasia of the primary canine ( LHPC ) . - pubmed
We focus on the Gobero region of Niger which preserves cemeteries containing skeletal remains from two occupation phases : ( 1 ) an Early Holocene / Kiffian fisher - forager phase , and ( 2 ) a Middle Holocene / Tenerian cattle pastoralism phase . - pubmed
METHODS : Clinical data from 236 patients with acute leukemia accompanied by bacterial bloodstream infection during July 2014 to November 2017 were retrospectively analyzed , 236 patients were divided into 5 groups ( & lt;0.05 ng / ml , 0.05- & lt;0.5 ng / ml , 0.5- & lt;2.0 ng / ml , 2.0- & lt;10.0 ng / ml and & gt;10.0 ng / ml ) according to PCT concentrations . - pubmed
After SRT de novo urinary incontinence complaints ( grade & gt;= 1 ) occurred in the respective acute and late phase in 6.1 % and 17.6 % of patients . - pubmed
METHODS : A total of 303 TNBC patients who underwent weekly paclitaxel plus carboplatin treatments followed by surgical resection were included in this study . - pubmed
Correction to : Biodiversity and selection for scrapie resistance in sheep : genetic polymorphism in eight breeds of Algeria . - pubmed
Roscoe Leaves , Methanolic Extract and Guaijaverin on Blood Glucose and Lipid Levels in a Type II Diabetic Rat Model . - pubmed
Oral acute treatment of streptozotocin ( STZ)-induced diabetic rats for 18 h with the C. - pubmed
Recent transcriptome studies of the infection of maize by the biotrophic pathogen Ustilago maydis are providing molecular insights into an ordered program of changes in gene expression and the deployment of effectors as well as key features of nutrient acquisition . - pubmed
Hypothyroidism in patients with hepatocellular carcinoma receiving cabozantinib : an unassessed issue . - pubmed
Antibiotics are associated with decreased progression - free survival of advanced melanoma patients treated with immune checkpoint inhibitors . - pubmed
Conclusion : These findings suggest that ATB use within 30 days prior to ICI initiation in patients with advanced melanoma may adversely affect patient outcomes . - pubmed
GdNPs solution which consists of 20 mg / mL NaGdF4 was injected into a nude mouse and two tumor - bearing mice . - pubmed
METHODS : A total of 176 men with unilateral inguinal hernia were randomized into two groups . - pubmed
BACKGROUND : Metal sensitivity as a cause for painful joint replacement has become increasingly prevalent ; however , there is a lack of reported clinical outcome data from total knee arthroplasty patients with metal allergies . - pubmed
Following revision , patients returned to the clinic at an interval of 6 weeks , 5 months , and 12 months for functional , pain , and satisfaction assessment . - pubmed
CONCLUSIONS : Patients presenting with a painful knee arthroplasty and positive metal LTT have improved pain scores , walking function , and range of motion following revision to a hypoallergenic component . - pubmed
Patients suffering from polycystic liver disease may develop Hepatic Venous Outflow Obstruction , Portal Vein Obstruction and/or Inferior Caval Vein Syndrome because of cystic mass effect . - pubmed
fatty and fibrotic infiltration ) are a common feature in individuals with lumbar spine pathology associated with low back pain , which often result in functional loss . - pubmed
CONCLUSIONS : There is increased fibrogenic gene expression in individuals with chronic disease when compared to acute disease , without significant differences in atrophic , myogenic , adipogenic , or inflammatory pathways , suggesting increased efforts should be made to prevent or reverse fibrogenesis in order to improve patient function in this population . - pubmed
Decompression for recurrent carpal tunnel syndrome provides significant functional improvement and patient satisfaction . - pubmed
Participants with FM ( n=148 ) will undergo a conditioning exercise period and be randomly allocated to one of four groups : ( 1 ) active tDCS and AE , ( 2 ) sham tDCS and AE , ( 3 ) active tDCS and non - aerobic exercise ( nAE ) or ( 4 ) sham tDCS and nAE . - pubmed
RESULTS : Sarcopenia was diagnosed in 27 patients ( 51.9 % ) . - pubmed
BACKGROUND : We present a rare case of neonatal cholestasis in a female infant with Gaucher Disease ( GD ) , who received liver transplantation . - pubmed
Despite early initiation of ERT , the patient had worsening of her liver failure and underwent a left lateral segment liver transplant from a living donor at 7 months of age . - pubmed
METHODS : The medical records of all 40 patients who received palliative radiotherapy for malignant ESCC from 2015 to 2017 were reviewed to determine the time course of key National Comprehensive Cancer Network guideline - supported workup and management steps . - pubmed
RESULTS : Patients treated for malignant ESCC after our QI intervention were more likely to undergo magnetic resonance imaging ( MRI ) of the entire spine ( 64 % v 44 % ; P = .013 ) and have a radiation oncology ( RO ) consultation before surgery ( 100 % v 27 % ; P = .002 ) . - pubmed
On subgroup analysis , initial trends toward delays in RO consultation for patients planning for surgery ( median , 3 days ) or for lack of prior cancer diagnosis ( median , 4 days ) were reduced to delays of 0 and 1 day , respectively , after the QI intervention . - pubmed
[ Clinical analysis of maxillofacial adipocytic neoplasia in children ] . - pubmed
Objective : To explore the clinical manifestations , diagnosis , treatment and prognosis of maxillofacial adipocytic neoplasia in children . - pubmed
Methods : The clinical data of 8 children with maxillofacial adipocytic neoplasia admitted to Shanghai Children 's Hospital from August 2014 to July 2019 were retrospectively analyzed , including 6 males and 2 females , aged from 8 months to 8 years 11 months , with an average age of 44 months . - pubmed
Results : Among the 8 patients , 5 were lipomas and 3 were lipoblastomas ; 4 were in the masseter muscle region of the parotid gland , 2 were in the parapharyngeal space and 1 was in the submandibular and nasal areas separately . - pubmed
All of 8 patients underwent surgical treatment without complications such as infection , facial paralysis , and salivary fistula . - pubmed
Conclusions : Lipoma and lipoblastoma are the main tumors of maxillofacial adipocytic neoplasia in children . - pubmed
The CAM6 strain showed in vitro antibacterial activity against selected enteropathogenic bacteria ( Escherichia coli strain NBRC 102203 and Salmonella enterica serovar Typhimurium 4.5.12 ) and commensal bacteria ( Klebsiella pneumoniae ATCC BAA-1705D-5 and Pseudomonas aeruginosa ATCC 15442 ) and resistance to all antibiotics except amoxicillin . - pubmed
Secondary aim was to evaluate impact of interventional radiology ( IR ) on delivery outcomes in patients with IP at MRI . - pubmed
METHODS : Twenty - six patients ( mean age 36.24y / o , SD6.16 ) with clinical risk - factors and echographic suspicion of IP underwent 1.5T - MRI . - pubmed
BACKGROUND : Diagnosis of soil - transmitted helminths ( STHs ) in developing countries is commonly based on microscopic detection of eggs in stool samples , using the Kato - Katz ( KK ) method , which has a poor sensitivity for detecting light intensity infections . - pubmed
We compared the performance of the KK method and real - time PCR in the framework of a randomized trial , which evaluated four novel treatments against Trichuris trichiura and concomitant STH infections . - pubmed
We report two cases of children who underwent emergent intubation for acute respiratory distress due to viral laryngotracheobronchitis and subsequently developed anterior laryngeal webs . - pubmed
We aimed to summarize reliable medical evidence by the meta - analysis of all published clinical trials that investigated the safety , tolerability , and immunogenicity of vaccine candidates against coronavirus disease 2019 ( COVID-19 ) , caused by severe acute respiratory syndrome coronavirus 2 ( SARS - CoV-2 ) . - pubmed
Curcuminoids , as potential phytochemicals extracted from Curcuma Longa L. , have been documented for their chemopreventive and antitumor activities against several types of malignancies . - pubmed
Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and affects over 6 million people worldwide . - pubmed
Evaluation in a mouse model of chronic T. cruzi infection did not show parasite growth inhibition , highlighting the difficulties encountered when going from in vitro assays onto preclinical drug developmental stages . - pubmed
A comparison of amnesia that is produced by two intravenous sedation techniques commonly used to reduce anxiety in ambulatory oral surgery patients showed that both techniques induce high levels of safe , predictable amnesia . - pubmed
A combination of therapeutic modalities was studied in 38 consecutive patients with intra - abdominally disseminated carcinoma of the ovary . - pubmed
Resection or destruction by electrocoagulation of all visible tumor was possible in 12 patients . - pubmed
For 18 of the remaining 26 patients in group 2 , elimination of all visible tumor was not possible technically , and in eight patients in group 3 , an irresectable tumor was found . - pubmed
Selective discrete intraaxoplasmic deposits of hydroxyapatite crystallites were observed in adult male rats subjected to experimental trauma to the lumbosacral spinal cord . - pubmed
[ Scintigraphic course control in children with pyelonephritis ( proceedings ) ] . - pubmed
Effects of hypoxia and glucose - free solution on the isolated rat portal vein were studied . - pubmed
[ Ultrastructure of neurosecretory cells of a ganglion of the ventral nervous chain of Eisenia foetida ( Sav . ) - pubmed
Peripheral blood mononuclear cells ( PBMCs ) from patients with Chediak - Higashi syndrome ( CHS ) exhibit minimal natural - killer - like cytotoxicity by standard 51Cr - release assays in vitro . - pubmed
concentrations in 16 patients with ARF and 12 healthy controls . - pubmed
CLINICAL FEATURES : Two patients who had been taking nitrofurantoin for several years , presented with severe liver failure . - pubmed
A third patient presented with acute hepatitis after six weeks of nitrofurantoin therapy . - pubmed
INTERVENTION AND OUTCOME : One of the patients with liver failure died and the other underwent a successful liver transplantation . - pubmed
Thirty patients with bedpartners complaining of their heavy snoring which had resulted in separate bedrooms were treated surgically . - pubmed
These 184 patients made up the study group and age , gender , injuries , Injury Severity Score ( ISS ) , ventilator days ( VD ) , complications , length of stay ( LOS ) , and outcome were noted . - pubmed
Genetic control of delayed type hypersensitivity to Mycobacterium leprae antigen . - pubmed
The mechanism of genetic control of Mycobacterium leprae - specific delayed type hypersensitivity ( DTH ) in mice was investigated in terms of footpad swelling response . - pubmed
Studies with various congenic and recombinant inbred strains of mouse revealed that M. - pubmed
Serum lipoprotein profile in children with celiac disease . - pubmed
To determine lipoprotein production in states of enterocyte dysfunction , we compared the serum lipid profiles in a group of 12 children with untreated celiac disease ( flat jejunal mucosa ) with the profiles in a control group of 10 children suffering from other intestinal diseases . - pubmed
Seven cases of occlusive ocular vascular disease affecting retinal and choroidal vessels were found among 84 consecutive patients with raised levels of anticardiolipin antibodies attending the lupus arthritis clinic at St Thomas 's Hospital from 1985 to 1987 . - pubmed
Characterization of growth parameters of a human hepatoma cell line cultured under serum - free conditions . - pubmed
In this paper the growth of PLC / PRF / 5 human hepatoma cell line in a serum- and hormone - free medium was investigated . - pubmed
The influence of starvation and natural refeeding on the rate of triacylglycerol / fatty acid substrate cycling in brown adipose tissue and different white adipose sites of the rat in vivo . - pubmed
A comparative study of results in patients with schistosomiasis and cirrhosis . - pubmed
Endoscopic sclerotherapy for bleeding esophageal varices was carried out in 78 patients with schistosomiasis ( Group I ) and 71 cirrhotic patients ( Group II ) . - pubmed
Throughout a follow - up period of at least 24 months , hemorrhage recurred in 13 % of the Group I patients , with one death ( 1 % ) . - pubmed
A comparison of patients with schistosomiasis and cirrhosis type A revealed no differences with respect to rebleeding or survival ( p greater than 0.05 ) . - pubmed
Differences were significant for bleeding recurrence and survival in Child B patients as compared with schistosomiasis patients ( p less than 0.025 ) . - pubmed
This result suggests that macrophages play a regulatory role on LT production and release by regional lymph nodes in human cancer . - pubmed
[ Studies on the cell - mediated immunity in regional lymph nodes from patients with gastric cancer ] . - pubmed
Plasma levels of cortisol were sampled for 24 hours in 32 endogenously depressed ( ED ) patients and 72 normal controls who also underwent the dexamethasone suppression test . - pubmed
Only seven ED patients had means 24h PC values higher than 2 SDs from the normal mean ( greater than 10 micrograms / dL ) . - pubmed
The mean plasma level of cortisol between 1 and 4 PM was found to be highly correlated with the means 24h PC value in ED patients , as has been previously reported in normal subjects and patients with various other diseases ( in which it also powerfully discriminated between hypersecretors and normosecretors ) . - pubmed
In a prospective study , 20 patients with a first acute myocardial infarction and no current treatment with diuretics or cardioactive drugs were randomized to treatment with intravenous timolol ( 10 patients ) or placebo ( 10 patients ) . - pubmed
Effect of angiotensin on water and electrolyte excretion in normal and cirrhotic rats . - pubmed
Proceedings : Cadmium poisoning effects on the rat dental tissues and bones . - pubmed
Mortality of diabetic patients treated surgically for lower limb infection and or gangrene . - pubmed
[ Course of chronic renal insufficiency in patients receiving a long - term low - protein diet ] . - pubmed
Rotavirus infection was frequently observed in pigs that were two to six weeks old and was rare in younger animals . - pubmed
Sucking pigs less than two weeks old appeared to be protected from the infection by passive immunity ; no antibodies were detected in the two- to three - week - old group , coinciding with an increased susceptibility to rotavirus infection . - pubmed
The antigenic specificity of the rotavirus isolates was confirmed by enzyme - linked immunosorbent assay test , using antibodies directed against the group - specific antigen of human rotavirus . - pubmed
To study the relationship between fiber size and vulnerability to ischemia , we produced partial infarction of the proximal posterior tibial nerve of Wistar rats by injecting arachidonic acid into the ipsilateral femoral artery . - pubmed
One hundred thirty - six patients underwent thrombolytic therapy for acute evolving myocardial infarction from June , 1981 , through December , 1982 . - pubmed
Postoperative hemorrhagic problems were minimal , and the incidences were no different from those for other coronary bypass patients . - pubmed
We injected antibacterial solutions into rabbit pericardium to investigate tissue injury . - pubmed
Growth of pre - B cells in cultures of bone marrow from children with acute lymphoblastic leukaemia and other diseases . - pubmed
Pre - B cells from the bone marrow of children with acute lymphoblastic leukaemia ( ALL ) survived up to 144 hr after the completion of treatment and divided in culture with maximum cell numbers at 24 hr . - pubmed
Pre - B cell numbers also increased in culture of morphologically normal marrows from treated and untreated patients with solid tumours , and probably in normal marrows from patients with non - malignant diseases . - pubmed
Elective repair of aneurysms has a low mortality , and 50 % of the patients live for at least 5 years . - pubmed
In 3 patients , 5 ears , the stenosis was congenital ; in 1 patient , 1 ear , traumatic ; and in 1 patient , 2 ears , secondary to chronic external otitis . - pubmed
We evaluated , in 128 patients with recurrent nephrolithiasis , the efficacy of special treatment programs for some of the common causes of nephrolithiasis , chosen on the basis of their ability to correct underlying physicochemical and physiologic derangements . - pubmed
Therapy included sodium cellulose phosphate for 18 patients with absorptive hypercalciuria , thiazide diuretics for 27 patients with absorptive hypercalciuria and for 10 with renal hypercalciuria , orthophosphate for eight patients with hypophosphatemic absorptive hypercalciuria , allopurinol for 21 patients with hyperuricosuric calcium oxalate nephrolithiasis , thiazide and allopurinol for 26 patients with absorptive hypercalciuria with hyperuricosuria , and high fluid intake and/or low calcium diet for 22 patients with normocalciuric nephrolithiasis . - pubmed
A retrospective study of 192 patients centered on the outcome of supraventricular arrhythmias after catheter ablation of the atrioventricular junction provided some useful information concerning the choice of pacing mode in these patients . - pubmed
Strains of Escherichia coli specifically modified in their respiratory chain have been used recently to re - evaluate the energetic efficiency of the bacterial respiration using chemostat cultures . - pubmed
In the second part of our experiments we studied the influence of acute and chronic hypoxia on the ascorbic acid content in liver , adrenal , plasma , cerebrospinal fluid and brain in 18 - day - old rats . - pubmed
Typical patterns in the EEG of 5 children with lissencephaly are presented . - pubmed
To determine the relationship between nutritional status and ethanol consumption , 250 chronically alcoholic men ( mean age 41 + /- 11 years ) entering an alcoholism treatment program were studied . - pubmed
DESIGN : Plasma samples were collected from 94 normotensive and 93 essential hypertensive subjects , the latter either previously defined by dietary salt sensitivity ( n = 43 ) , or prospectively studied on both low- ( & lt ; 50 mmol / day ) and high - salt ( & gt ; 200 mmol / day ) diets ( n = 16 ) . - pubmed
Of these , 4 of 25 were from individuals infected with human immunodeficiency virus ( HIV ) and 3 of 27 were not infected with HIV . - pubmed
Investigators have compiled extensive experience with mitomycin in the treatment of patients with breast cancer . - pubmed
Such regimens may yield quicker responses , and thus improve survival , in patients with breast cancer . - pubmed
The retinas could be evaluated in all the examined dogs , and revealed no abnormalities except for one case of focal retinopathy . - pubmed
Investigation of unknown rashes in these patients includes skin biopsy , which clearly differentiates leukocytoclastic vasculitis and erythema exsudativum multiforme with lymphocytic vasculitis from cutaneous manifestations of GvHD . - pubmed
Special stains may reveal bacteria and fungus in septicemic patients . - pubmed
It has been reported that the F - Dopa ( FD ) uptake in patients with idiopathic Parkinson ' s disease ( PD ) decreased significantly in the caudate and putamen when compared to controls . - pubmed
The FD uptake was measured by PET with 6 - L -[ 18F ] fluorodopa in 17 patients with PD . - pubmed
The caudate and the putaminal FD uptake ratios in the patients with PD decreased as their clinical stages advanced . - pubmed
The FD / PET study therefore effectively demonstrated the severity of the clinical symptoms of rigidity and bradykinesia in patients with PD in correlation with a decrease in the FD uptakes in the caudate and the putamen , and it also demonstrated that the severity of tremor might have a different mechanism from that of such other symptoms as rigidity and bradykinesia . - pubmed
OBJECTIVE : An epidemiological study conducted between 1987 and 1989 in a single school district in the southeastern United States investigated the incidence , transition probabilities , and risk factors for major depressive disorder ( MDD ) and dysthymia in adolescents aged 11 to 16 years . - pubmed
METHOD : Diagnoses were based on the Schedule for Affective Disorders and Schizophrenia for School - Age Children , which was administered to 247 mother - adolescent pairs at 12 - month intervals . - pubmed
A retrospective study was conducted to describe airway intervention required to manage patients with craniofacial syndromes and diseases involving the midface and mandible ( i.e. - pubmed
Calf veins are one of the most common sites for deep vein thrombosis ( DVT ) but the management of patients with calf vein thrombosis differs . - pubmed
A study was carried out where 50 patients with isolated calf vein thrombosis were followed over a one year period to determine the long term outcome in the calf veins . - pubmed
Data from 400 consecutive elective ambulatory operations for inguinal hernia under unmonitored local anaesthesia with limited pre - operative testing were prospectively obtained by the use of standardised files and questionnaires to assess the feasibility , patient satisfaction and potential cost reductions for such a technique . - pubmed
Cardioversion , usually by transthoracic direct current shock , restores sinus rhythm in & gt ; 80 % of patients , but recurrence of AFib over the weeks and months that follow decreases the value of this strategy . - pubmed
In this study , we assessed the effect of chronic alcohol ingestion on bacterial clearance , survival , and cytokine mRNA and protein expression in mice with Klebsiella pneumonia . - pubmed
Effects of birth weight and postnatal nutrition on neonatal sheep : I. - pubmed
CT bone density was determined using the OsteoQuant in 14 individuals with OI - type I who ranged in ages from 8 months to 45 years . - pubmed
falciparum infection rates and density , whereas P. - pubmed
Susceptibility of chacma baboons ( Papio ursinus orientalis ) to infection by hepatitis B virus . - pubmed
BACKGROUND : Because baboons are being considered as a source of xenografts for human liver transplantation in patients with hepatitis B virus- ( HBV ) induced cirrhosis to forestall infection of the graft by the virus , we undertook a study to ascertain if baboons are resistant to HBV infection . - pubmed
METHODS : Six chacma baboons were inoculated with serum containing HBV and were followed for 52 weeks to detect transmission of infection . - pubmed
CONCLUSIONS : Chacma baboons are susceptible to HBV infection and appear to develop a chronic carrier state . - pubmed
The use of xenografts from baboons should preferably be avoided , but if they are used again for HBV - infected patients it would be prudent to treat the patients as if they had received an organ from a human donor . - pubmed
Temporal lobe asymmetry in patients with Alzheimer ' s disease with delusions . - pubmed
Temporal asymmetry was computed as the right / left ( R / L ) ratio of the WTH in 22 non - delusional and 19 delusional patients with Alzheimer ' s disease . - pubmed
Delusional patients had paranoid delusions ( of theft , jealousy , persecution ) . - pubmed
None of the patients had misidentifications or other delusions of non - paranoid content . - pubmed
Enoxaparin reduces brain edema , cerebral lesions , and improves motor and cognitive impairments induced by a traumatic brain injury in rats . - pubmed
Enoxaparin , a low - molecular weight heparin , which is efficacious in models of myocardial and brain ischemia was studied in lateral fluid percussion - induced TBI in rats . - pubmed
Therefore , enoxaparin could be a candidate drug to treat acute brain - injured patients . - pubmed
In comparison to primary wound closure with local tissue , the technique presented in this study reduces the severity of postoperative pain and allows faster rehabilitation in patients because of a better wound - healing process . - pubmed
BACKGROUND : It remains unknown whether there is any important clinical advantage to the use of either a bioprosthetic or mechanical valve for patients with native or prosthetic valve endocarditis . - pubmed
METHODS : Between 1964 and 1995 , 306 patients underwent valve replacement for left - sided native ( 209 patients ) or prosthetic ( 97 patients ) valve endocarditis . - pubmed
Long - term survival was superior for patients with native valve endocarditis ( 44+/-5 % at 20 years ) compared with those with prosthetic valve endocarditis ( 16+/-7 % at 20 years ) ( p & lt ; 0.003 ) . - pubmed
Outcome of cataract surgery in patients with retinitis pigmentosa . - pubmed
METHODS : A retrospective analysis was undertaken of a continuous series of 142 eyes of 89 patients with retinitis pigmentosa undergoing cataract surgery between 1985 and 1997 . - pubmed
CONCLUSIONS : Cataract surgery for relatively minor lens opacities is beneficial in patients with retinitis pigmentosa , and most report subjective improvement of visual symptoms . - pubmed
Like the two U.S. strains of human HEV , an extra G residue immediately proceeding the poly(A ) tail was identified in swine HEV . - pubmed
The 5 ' NCR of swine HEV also differed from many HEV strains : it lacks an A residue at its 5 ' very end , and the extra 9 nucleotides in the US-2 strain . - pubmed
In the 3 ' NCR , swine HEV shared 90 - 91 % nucleotide sequence identities with the US-1 and US-2 strains but only about 58 - 65 % identities with other HEV strains . - pubmed
This study further suggests that the US-1 and US-2 strains of human HEV may be of swine origin . - pubmed
Double - blind , placebo - controlled study of L - carnosine supplementation in children with autistic spectrum disorders . - pubmed
We investigated 31 children with autistic spectrum disorders in an 8 - week , double - blinded study to determine if 800 mg L - carnosine daily would result in observable changes versus placebo . - pubmed
After 8 weeks on L - carnosine , children showed statistically significant improvements on the Gilliam Autism Rating Scale ( total score and the Behavior , Socialization , and Communication subscales ) and the Receptive One - Word Picture Vocabulary test ( all P & lt ; .05 ) . - pubmed
We present a patient who suffered from sleep attacks after starting entacapone in addition to levodopa . - pubmed
Preliminary studies have demonstrated a significant reduction in SRMD bleeding for patients receiving PPI prophylaxis . - pubmed
PPIs may become an effective tool for reducing the incidence of SRMD in critically ill patients . - pubmed
The use of acute normovolemic hemodilution in patients undergoing cardiac surgery . - pubmed
To test this hypothesis , we analyzed invasive recordings from epileptic patients while they performed a spatially immersive , virtual taxi driver task . - pubmed
[ Airway hyperreactivity in patients with allergic and non - allergic rhinitis ] . - pubmed
Asthma can affect 40 % of the patients with rhinitis and 80 % of asthmatics present rhinitis . - pubmed
OBJECTIVE : To determine if there is bronchial hyper - responsiveness in patients with allergic and not allergic rhinitis , by correlating with the eosinophilia in nasal mucosa . - pubmed
Twenty - eight patients concluded the study , they were divided in two groups : a group of 15 patients with diagnosis of allergic rhinitis and another group of 13 patients with diagnosis of non allergic rhinitis . - pubmed
RESULTS : Fifty - six spirometry studies were performed and only 4 patients ( 26.6 % ) with diagnosis of allergic rhinitis presented fall of the FEV1 in the bronchial challenge in comparison with the group of non allergic rhinitis in which there were no changes in the FEV1 later to the bronchial challenge . - pubmed
CONCLUSIONS : Nonspecific bronchial hyper - responsiveness is present in patients with allergic rhinitis . - pubmed
[ Human listeriosis . - pubmed
Dose - dense regimen of temozolomide given every other week in patients with primary central nervous system tumors . - pubmed
BACKGROUND : Temozolomide has shown activity and limited toxicity in patients with primary brain tumors at doses of 150 - 200 mg / m(2)/day on days 1 - 5 every 4 weeks . - pubmed
In this study , a new alternative dose - dense regimen of temozolomide was explored in patients with recurrent brain tumors . - pubmed
PATIENTS AND METHODS : In this study , we evaluated the safety , dose - limiting toxicity , maximum tolerated dose , recommended dose and activity of temozolomide given on days 1 - 3 and 14 - 16 every 28 days ( one cycle ) . - pubmed
The starting daily dose was 200 mg / m(2 ) in a group of at least six patients , with subsequent increments of 50 mg / m(2 ) in groups of at least 12 patients until unacceptable toxicity was reached . - pubmed
RESULTS : Seventy patients with brain tumors entered this study . - pubmed
Grade 3 - 4 thrombocytopenia was observed in 0/7 , 1/13 , 5/38 and 4/12 patients treated at doses of 200 , 250 , 300 and 350 mg / m(2)/day , respectively . - pubmed
Grade 3 - 4 neutropenia was observed in 1/7 , 0/13 , 3/38 and 4/12 patients treated with 200 , 250 , 300 and 350 mg / m(2)/day temozolomide , respectively . - pubmed
At a dose of 350 mg / m(2 ) , sustained grade 2 - 3 thrombocytopenia did not allow treatment to be resumed at day 14 in & gt;40 % of patients , and this dose was considered to be the maximum tolerated dose . - pubmed
CONCLUSIONS : Temozolomide can be given safely using a dose - dense regimen of 300 mg / m(2)/day for 3 consecutive days every 2 weeks in patients with recurrent brain tumors . - pubmed
OBJECTIVE : To study the relation between human polyomavirus BK ( BKV ) infection and the risk of developing nephropathy , we monthly investigated the BKV load in urine and serum samples from 15 renal transplant recipients during 6 months in relation with immunosuppressive treatment and renal function . - pubmed
RESULTS : Fifty - three percent of the patients had quantifiable BKV - DNA both in urine and serum samples but there was no relation between viruria and viraemia . - pubmed
Seventy - five percent of the patients on FK506 therapy and 71.4 % of those on CyA therapy showed activation of BKV infection . - pubmed
In ten patients serum creatinine levels were & lt;2 mg / dl for the whole study , even if 80 % presented BKV viruria and/ or viraemia . - pubmed
On the other hand , in 4 patients serum creatinine levels reached higher values , but they were BKV viruria and/or viraemia negative during the study . - pubmed
CONCLUSIONS : Our results suggest that viruria and viraemia may reflect independent BKV reactivation in different tissues . - pubmed
We aimed to determine whether an individualized course of dexamethasone given to preterm babies at risk of chronic lung disease reduced the total dose of dexamethasone administered and reduced side - effects compared with a standard 42 - day course . - pubmed
CONCLUSION : The individualized course of dexamethasone used in this study reduced the total dose of dexamethasone administered but did not significantly reduce side - effects of treatment or alter outcome in infants at risk of chronic lung disease . - pubmed
High sensitivity of northern pike larvae to UV - B but no UV - photoinduced toxicity of retene . - pubmed
However , pike larvae were very sensitive to UV - B even in low doses , indicated as severe neurobehavioral disorders . - pubmed
Monitoring of pike with the neurobehavioral syndrome revealed substantial late mortality . - pubmed
In this study , in which 12 - day - old mouse embryos were used because of a high frequency of " natural cell death " due to changing inner ear morphology [ Kaufman , M.H. - pubmed
PATIENTS AND METHODS : Between January 1999 and August 2002 , 43 patients undergoing laparoscopic GB for morbid obesity underwent upper gastrointestinal endoscopy , 24 - hour pH monitoring , and stationary esophageal manometry before GB and between 6 and 18 months postoperatively . - pubmed
A few patients developed massive postoperative reflux . - pubmed
Patients presenting to emergency departments after cocaine ingestion frequently present with a chief complaint of chest pain . - pubmed
RESULTS : The binding potential of [ 11C ] d - threo - methylphenidate was reduced in the striatum in SCA2 and SCA3 ; in contrast to patients with Parkinson disease , no increased susceptibility of the putamen was evident . - pubmed
A trend toward increased regional cerebral glucose metabolism was found in the temporal cortex of all patients with SCA , pronounced in SCA6 . - pubmed
Non - coplanar PCB - mediated modulation of human leukocyte phagocytosis : a new mechanism for immunotoxicity . - pubmed
CMD : a Cotton Microsatellite Database resource for Gossypium genomics . - pubmed
Exercise - induced myocardial ischemia in a patient with dislocated right coronary artery orifice in the right sinus of Valsalva . - pubmed
In db / db and HFD mice , gene transcripts associated with mitochondrial ATP production , energy uncoupling , mitochondrial ribosomal proteins , outer and inner membrane translocases , and mitochondrial heat - shock proteins were decreased in abundance , compared with db/+ and standard - fat diet - fed control mice , respectively . - pubmed
Adipose mitochondrial biogenesis was overwhelmingly suppressed in both mouse models of diabetes / obesity and globally induced by RSG . - pubmed
METHODS : The cases of 106 patients with osteochondritis dissecans of the capitellum were studied retrospectively . - pubmed
Acidosis and lipopolysaccharide from Escherichia coli B:055 cause hyperpermeability of rumen and colon tissues . - pubmed
Atypical dermatophilosis of sheep in Kenya . - pubmed
Clinical diagnosis of ovine dermatophilosis was made and confirmed by direct microscopic examination as well as isolation and identification of Dermatophilus congolensis from scab material from the affected sheep . - pubmed
The paper highlights atypical dermatophilosis of sheep and we believe that this is the first published report of an outbreak of ovine dermatophilosis in Kenya . - pubmed
BACKGROUND : Despite disproportionately high rates of hepatitis C ( HCV ) among patients with severe mental illness , to date , there is scant empirical data available regarding antiviral therapy outcomes within this population . - pubmed
OBJECTIVE : To compare antiviral therapy completion and response rates between HCV patients with vs those without schizophrenia ( SCHZ ) . - pubmed
All patients confirmed to have SCHZ and to have received antiviral therapy between 1998 and 2006 ( n = 30 ) were compared with a control group of demographically matched ( HCV genotype , age , race , gender ) patients with no history of SCHZ ( n = 30 ) . - pubmed
CONCLUSION : Our retrospective chart review suggests that patients with SCHZ complete and respond to antiviral therapy for HCV at rates comparable with those without SCHZ . - pubmed
High prevalence of neuropathy in patients with impaired 60 - minute oral glucose tolerance test but normal fasting and 120 - minute glucose levels . - pubmed
Polyneuropathy was found in 44.4 % , 28.5 % , and 50.0 % of patients with IGT , IFG and DM respectively . - pubmed
The prevalence of polyneuropathy was significantly higher in patients with impaired 60 - min than OGTT normal subjects ( 52.4 % vs 21.7 % p=0.003 ) . - pubmed
CONCLUSION : Since the prevalence of neuropathy in patients with impaired 60 - min glucose levels is high , it would be valuable to look at 60 - min glucose levels to detect abnormal glucose metabolism and the neuropathy earlier in the course . - pubmed
We conducted a retrospective study comparing 450 consecutive patients with full - thickness gastric injury with 983 patients without gastric injury during the same time period . - pubmed
[ Brain abscess due to Mycobacterium tuberculosis ] . - pubmed
METHODS : The subjects were 22 healthy volunteers and 10 patients with proton - pump inhibitor ( PPI ) dependent gastroesophageal reflux disease ( GERD ) . - pubmed
RESULTS : The mean primary peristaltic amplitude associated with swallowing was 65.6+/-47.4 mmHg in the volunteer group , and 28.0+/-25.6 mmHg in the GERD group . - pubmed
OBJECTIVE : Joint - preserving osteotomies in patients with symptomatic varus malalignment of the ankle . - pubmed
RESULTS : Twelve patients with an osteotomy of the distal tibia presented with a significant reduction of pain on a visual analog scale ( p = 0.0001 ) and an increased range of motion of 33 degrees ( 5 - 55 degrees ) preoperatively compared to 39 degrees ( 25 - 50 degrees ) postoperatively . - pubmed
All 18 patients treated with a Z - shaped calcaneal osteotomy reported pain relief with osseous consolidation after 6 months . - pubmed
We report a 43 - year - old woman with PCALCL who had generalized skin involvement accompanied by involvement of one peripheral draining lymph - node region . - pubmed
Tumor reduction rate predicts early recurrence in patients with breast cancer failing to achieve complete response to primary chemotherapy . - pubmed
The correlation between tumor reduction rate derived from MRI and occurrence of early events in breast cancer patients was analyzed retrospectively . - pubmed
CONCLUSIONS : The evaluation of tumor reduction rates on MRI was considered to be useful for predicting early outcome among breast cancer patients who can not achieve pCR after PCT . - pubmed
Treatment of patients with keratoconjunctivitis sicca with Optive : results of a multicenter , open - label observational study in Germany . - pubmed
OBJECTIVE : To evaluate the efficacy and tolerability of Optive , a new dry eye product containing sodium carboxymethylcellulose ( 0.5 % ) and glycerol ( 0.9 % ) , in patients with keratoconjunctivitis sicca ( KCS ) . - pubmed
METHODS : This was a non - interventional and observational study including patients with dry eye who required a change of medication or were naive to dry eye treatment ( N = 5,277 ) . - pubmed
RESULTS : The severity of KCS was mild in 18.6 % , moderate in 59.9 % , and severe in 21.5 % of patients based on physicians ' assessment . - pubmed
STUDY DESIGN : Eighty - five Thai subjects ( 29 men , 56 women ) who had MetS according to the International Diabetes Federation definition were evaluated for CAC detected on panoramic radiographs . - pubmed
CONCLUSION : Thai people with MetS have high prevalence of radiographically detectable carotid artery calcifications . - pubmed
The most common diagnosis leading to cardiac arrest was acute myocardial infarction ( 46 of 135 patients ) . - pubmed
INCIDENCE OF GASTRIC ULCER IN ALBINO RATS FED DIETS DEFICIENT IN VITAMIN B ( B ( 1 ) ) . - pubmed
73 per cent of a group of albino rats whose diet was deficient in vitamin B have been found to have ulcerations of the gastric mucosa . - pubmed
Of 74 observed lesions eight were chronic , indurated ulcers resembling chronic peptic ulcer in man . - pubmed
Ectopic human mesenchymal stem cell - coated scaffolds in NOD / SCID mice : an in vivo model of the leukemia niche . - pubmed
When implanted subcutaneously in NOD / SCID mice , these niches supported engraftment of primary human acute myeloid leukemia cells . - pubmed
To better understand the evolution of CIV since its emergence , and particularly its microevolution in spatially restricted populations , we examined multiple gene segments of CIV from dogs resident in two large animal shelters in New York City during the period 2006 to 2009 . - pubmed
METHODS : We describe an elderly , yet healthy man who sought medical attention for subarachnoid hemorrhage . - pubmed
DESIGN : We retrospectively studied 30 consecutive cases of histologically proven rhabdomyosarcoma in children aged 0 - 15 years extracted from the database of the Cancer Registry of the Center of Tunisia for the period 1993 - 2007 . - pubmed
RESULTS : Rhabdomyosarcomas represented 53.6 % of soft tissue sarcomas and 3.8 % of all children cancer cases registered during this period . - pubmed
The study included 686 children ( 2 - 16 years of age ) with presumed AA managed by appendectomy . - pubmed
RESULTS : Of the 686 children who underwent surgery for suspected AA , 34 ( 5 % ) had a normal appendix ( negative appendectomy rate ) . - pubmed
Children in the AA group were younger ( 10.9 + -3.2 vs. 12.1 + -2.3 years , p=0.004 ) , had higher fever ( 36.9 + -0.7 C vs. 37.4 + -0.8 C , p=0.004 ) , WBC ( 14.8 + -4.8 vs. 10.5 + -4.6x103 / mL , p<0.0005 ) , and neutrophil counts ( 77.2 + -11.1 % vs. 64.0 + -15.9 % , p<0.0005 ) on admission , and larger appendicular diameters on ultrasound ( US ) examination ( 0.9 + -0.2 cm vs. 0.7 + -0.08 cm , p<0.0005 ) . - pubmed
Effect of body weight on the outcome of displaced intracapsular fracture neck of femur treated by internal fixation ; a clinical study of 198 patients . - pubmed
A total of 198 patients with such injuries treated by closed reduction and internal fixation , were recruited retrospectively . - pubmed
Patients were followed up until fracture endpoint ( union or non - union ) with a minimum follow up of 100 days . - pubmed
The mean body weight for the 118 patients without fracture healing complications was 64.6 kg versus 61.8 kg for the 80 patients with complications , a difference that was not statistically significant ( p=0.17 ) . - pubmed
Temporal changes in the management and outcome of Canadian diabetic patients hospitalized for non - ST - elevation acute coronary syndromes . - pubmed
Patients with diabetes were older ; were more likely to have prior cardiac history including myocardial infarction , revascularization , and heart failure ; and had worse Killip class and higher GRACE risk score ( all P & lt ; .001 ) . - pubmed
However , diabetic patients were less likely to undergo coronary angiography ( 52.5 % vs 57 % , P & lt ; .001 ) or revascularization ( 28.4 % vs 33.4 % , P & lt ; .001 ) . - pubmed
Overall , compared with the group without diabetes , diabetic patients had higher unadjusted rates of in - hospital mortality ( 3.0 % vs 1.6 % , P & lt ; .001 ) . - pubmed
BACKGROUND AND PURPOSE : The European Cooperative Acute Stroke Study ( ECASS ) III extended the thrombolysis time window for patients with stroke from 3 to 4.5 hours after symptom onset . - pubmed
METHODS : The present study was based on a prospective database of 93 hospitals of the Stroke Register of Northwestern Germany , which included 91 805 patients with ischemic stroke admitted between January 2007 and December 2009 . - pubmed
The proportion of patients with stroke with a door - to - needle time<60 minutes increased after publication of ECASS III ( OR , 1.49 ; 95 % CI , 1.37 to 1.63 ) . - pubmed
Speech and language delays in preschool children . - pubmed
Type 2 diabetes in obese patients with body mass index of 30 - 35 kg / m2 : sleeve gastrectomy versus medical treatment . - pubmed
Our objective was to compare the effects of LSG and medical therapy on patients with T2DM and a BMI of & lt;35 kg / m(2 ) . - pubmed
METHODS : A total of 18 nonmorbidly obese patients with T2DM , diagnosed according to the American Diabetes Association guidelines , were consecutively enrolled . - pubmed
RESULTS : In group A , T2DM resolution was achieved in 8 ( 88.8 % ) of the 9 patients ( T2DM duration 5.2 yr ) . - pubmed
Hypertension was controlled in all 8 of 9 patients . - pubmed
In 1 patient , obstructive sleep apnea syndrome improved . - pubmed
In group B , all 9 patients continued to have T2DM and required hypertensive and hypolipemic therapies throughout the observation period . - pubmed
At baseline , 3 patients were affected by obstructive sleep apnea syndrome and remained affected 1 year later . - pubmed
CONCLUSION : The results of the present study have confirmed the efficacy of LSG in the treatment of nonmorbidly obese T2DM patients , with a remission rate of 88.8 % without undesirable excessive weight loss . - pubmed
A novel Gram - staining - negative , coccoid , non - motile bacterium , designated strain V1 - 41(T ) , was isolated from a sample of marine sediment collected , at a depth of 200 m , from Kongsfjorden ( an inlet on the west coast of Spitsbergen , an island that forms part of the Svalbard archipelago in the Arctic Ocean ) . - pubmed
In DNA - DNA hybridizations , however , the levels of relatedness between strain V1 - 41(T ) and O. - pubmed
litoralis DSM 15406 ( T ) and between the novel strain and O. - pubmed
The type strain is V1 - 41(T ) ( = CCUG 58690(T ) = KCTC 23013(T ) = NBRC 106171(T ) ) . - pubmed
In obstructive sleep apnea patients , elevated activity of the lingual muscles during wakefulness protects the upper airway against occlusions . - pubmed
A possibly related form of respiratory neuroplasticity is present in rats exposed to acute and chronic intermittent hypoxia ( CIH ) . - pubmed
Early ultrasonographic finding of septic thrombophlebitis is the main indicator of central venous catheter removal to reduce infection - related mortality in neutropenic patients with bloodstream infection . - pubmed
BACKGROUND : Septic thrombophlebitis increases patient morbidity and mortality following metastatic infections , pulmonary emboli , and/or septic shock . - pubmed
Central venous catheter ( CVC ) removal for occult septic thrombophlebitis challenges current strategy in neutropenic patients . - pubmed
PATIENTS AND METHODS : We prospectively evaluated infection - related mortality in 100 acute leukemia patients , with CVC - related bloodstream infection ( CRBSI ) after chemotherapy , who systematically underwent ultrasonography to identify the need for catheter removal . - pubmed
Their infection - related mortality was compared with that of a historical cohort of 100 acute leukemia patients , with CRBSI after chemotherapy , managed with a clinically driven strategy . - pubmed
RESULTS : In the prospective series , 30/100 patients required catheter removal for ultrasonography - detected septic thrombophlebitis after 1 median day from BSI onset ; 70/100 patients without septic thrombophlebitis retained their CVC . - pubmed
In the historical cohort , 60/100 patients removed the catheter ( persistent fever , 40 patients ; persistent BSI , 10 patients ; or clinically manifest septic thrombophlebitis , 10 patients ) after 8 median days from BSI onset ; 40/100 patients retained the CVC because they had not clinical findings of complicated infection . - pubmed
CONCLUSION : Ultrasonography is an easy imaging diagnostic tool enabling effective and safe management of patients with acute leukemia and CRBSI . - pubmed
Acinetobacter baumannii causes severe infections in compromised patients , who present an iron - limited environment that controls bacterial growth . - pubmed
Nasolacrimal duct obstruction as a complication of iodine-131 therapy in patients with thyroid cancer . - pubmed
This study reports on symptomatic and asymptomatic nasolacrimal duct obstruction ( NLDO ) as complications of high - dose radioiodine therapy in these patients . - pubmed
METHODS : Eighty - one cases were randomly selected from a population of radioiodine - treated differentiated thyroid carcinoma patients and were enrolled in a historical cohort study . - pubmed
All the patients were suffering from right heart failure and pulmonary hypertension , and the preoperative mean pulmonary artery pressure ( mPAP ) was 51.2 + /- 10.2 mmHg , and the pulmonary vascular resistance ( PVR ) was 894.2 + /- 207.7 dyne x sec(-1 ) x cm(-5 ) . - pubmed
The patients ' symptoms such as shortness of breath , and dyspnea improved and they were discharged without any serious complications . - pubmed
We demonstrated that animals exposed to cigarettes in the prenatal period had increased the risk for psychotic symptoms in adulthood . - pubmed
METHODS This study was carried out on fifty ( 50 ) patients with oral sub mucous fibrosis . - pubmed
[ Clinical features of antiviral therapy - induced thyroid disease in patients with chronic hepatitis C ] . - pubmed
OBJECTIVE : To investigate the clinical features of thyroid disease occurring in response to antiviral therapy in patients with chronic hepatitis C ( CHC ) . - pubmed
METHODS : Eighty - two patients diagnosed with CHC were recruited for study from our hospital between 2009 and 2010 . - pubmed
Differential expression of biomarkers was assessed between patients who developed thyroid disorder and those who did not . - pubmed
When the two groups of patients who did or did not develop thyroid disease were compared , there was no difference in the amount of patients who achieved sustained virological response . - pubmed
CONCLUSION : Antiviral - induced thyroid disease in patients with refractory hepatitis C manifests as clinically - detectable abnormalities in serum levels of thyroid autoantibody and markers of hypothyroidism . - pubmed
Gold ( III )- dithiocarbamato peptidomimetics in the forefront of the targeted anticancer therapy : preclinical studies against human breast neoplasia . - pubmed
Among all , we focused on two compounds and tested them on human MDA - MB-231 ( resistant to cisplatin ) breast cancer cell cultures and xenografts , discovering the proteasome as a major target both in vitro and in vivo . - pubmed
53 % inhibition of breast tumor growth in mice was observed after 27 days of treatment at 1.0 mg kg(-1 ) d(-1 ) , compared to control . - pubmed
Remarkably , if only the most responsive mice are taken into account , 85 % growth inhibition , with some animals showing tumor shrinkage , was observed after 13 days . - pubmed
BACKGROUND : There is a growing interest in measuring cerebral autoregulation in patients with acute brain injury . - pubmed
METHODS : We performed 37 simultaneous recordings of BP and cerebral blood flow velocity in 15 patients with acute brain injury . - pubmed
Genes relevant with osteoarthritis by comparison gene expression profiles of synovial membrane of osteoarthritis patients at different stages . - pubmed
BACKGROUND : This study aimed to identify biological markers about osteoarthritis ( OA ) which is a polygenic disease by investigating the gene expression profiles of the synovium samples from early - stage and end - stage OA patients for the diagnosis and treatment of OA . - pubmed
METHODS : The gene expression profile of GSE32317 was downloaded from Gene Expression Omnibus ( GEO ) database , including 10 samples from early - stage OA patients and 9 samples from end - stage OA patients . - pubmed
Two species of microalgae Chlorella pyrenoidosa , Scenedesmus obliqnus and a red worm Chironomidae larvae were selected as test organisms in determining the acute toxicity effects of Cr ( VI ) , 2,4,6 - trichlorophenol and nitrobenzene . - pubmed
Numerous agents derived from plants have anti - gout potential . - pubmed
In the rare human studies , colchicine from Colchicum autumnale showed anti - inflammatory effects while for other plant extracts , although revealing anti - gout potential , further phytochemical investigations are needed to identify their active constituents . - pubmed
Besides , the plants which give antioxidant activities are much potent in the management of gout and need to be further investigated . - pubmed
We recently reported the characteristics of a HD patient - derived iPSC carrying 72 CAG repeats ( HD72 - iPSC ) . - pubmed
In this study , we investigated the in vivo roles of HD72 - iPSC in the YAC128 transgenic mice , a commonly used HD mouse model carrying 128 CAG repeats . - pubmed
METHODS : We recruited 357 qualified participants from consecutive patients with acute ischemic stroke who came to the stroke registry center in Sichuan Provincial People 's Hospital , Chengdu , China . - pubmed
In each subject , airway with conventional pure tone audiometry from 125 to 8000 Hz was assessed using a clinical audiometer ( model 622 , Minimate , Madsen ) Clinical case : Hearing loss at all frequencies was found in all eight patients , from mild to severe in both ears . - pubmed
Clostridium difficile carriage in hospitalized cancer patients : a prospective investigation in eastern China . - pubmed
Vascular changes in the developing rat retina in response to hypoxia . - pubmed
This study explored the effects of exemplar changes on visual object recognition in patients with schizophrenia and paired control subjects . - pubmed
Overall , performance was better on the inclusion task than on the exclusion task ; schizophrenia patients performed worse than controls on the inclusion task but not the exclusion task , misrecognizing different exemplars more often than healthy controls . - pubmed
[ Resistance to azithromycin of Neisseria gonorrhoeae strains isolated in Poland in 2012 - 2013 years ] . - pubmed
METHODS : Sixty five Neisseria gonorrhoeae strains isolated from patients of the Department of Dermatology and Venereology in Warsaw in the second half of 2012 and first of 2013 were investigated . - pubmed
CONCLUSIONS : The percentage of azithromycin resistant Neisseria gonorrhoeae strains is increasing in Poland and the antibiotic should not be used in monotherapy as gonorrhoea patients . - pubmed
Practical management of anticoagulation in patients with atrial fibrillation . - pubmed
The attendees continued to work toward consensus on these topics , and present the key findings of this roundtable in a state - of- the - art review focusing on the practical aspects of anticoagulation care for the patient with atrial fibrillation . - pubmed
Causative factors were vulvar cancer in 14 patients , extramammary Paget ' s disease in 2 , vulvar dysplasia in 5 , and combined vulvar and vaginal cancer in 2 patients . - pubmed
Xylene - induced ear edema , carrageenan - induced paw edema and acetic acid - induced vascular permeability test were used to investigate the anti - inflammatory activities of GL in mice . - pubmed
BACKGROUND AND PURPOSE : Reducing body temperature can prolong tolerance to ischemic injury such as stroke or myocardial infarction , but is difficult and uncomfortable in awake patients because of shivering . - pubmed
RESULTS : All ten subjects experienced shivering on placebo days , with shivering beginning at a mean ( SD ) temperature of 36.6 ( 0.3 ) C. The mean lowest temperature after placebo was 36.0 ( 0.3 ) C ( range 35.7 - 36.5 C ) . - pubmed
CONCLUSION : Dexmedetomidine decreases shivering in normal volunteers . - pubmed
Intersphincteric anal lipofilling with micro - fragmented fat tissue for the treatment of faecal incontinence : preliminary results of three patients . - pubmed
In February 2014 we treated 3 patients with faecal incontinence . - pubmed
Each patient reported an improved Wexner incontinence score at 1 month after the procedure . - pubmed
MATERIAL AND METHODS : The study included 2049 patients undergoing transrectal ultrasound - guided 12 - core prostate biopsy used in the diagnosis of prostate cancer . - pubmed
To prevent development of voiding disorders , the patients also received oral alpha blockers for 30 days starting the day before the procedure . - pubmed
Significance statement : Successful restoration of hearing in deaf subjects by means of a cochlear implant requires a healthy spiral ganglion cell population . - pubmed
Nude mice are important in vivo model for characterization of cell malignancy behavior ; however , many cancer cells fail to form tumors in it . - pubmed
CONCLUSION : Collectively , these findings highlight the role of distinct adipose depots in mice in the development of obesity and emphasize the importance of selecting specific depots to study the effects of therapeutic interventions on adipose tissue function . - pubmed
However , emerging evidence in humans and animal models suggests that dysregulated circuit function and gene expression across multiple brain regions drive depressive phenotypes . - pubmed
Monitoring of Tumor Growth with [ ( 18 ) F ]- FET PET in a Mouse Model of Glioblastoma : SUV Measurements and Volumetric Approaches . - pubmed
This study investigates the potential of positron emission tomography ( PET ) using O -( 2 -( 18 ) F - fluoroethyl )- L - tyrosine ( [ ( 18 ) F ]- FET ) to determine tumor growth in a murine glioblastoma ( GBM ) model - including estimation of the biological tumor volume ( BTV ) , which has hitherto not been investigated in the pre - clinical context . - pubmed
[ ( 18 ) F ]- FET PET with standard SUV measurements is feasible for glioma imaging in the GBM mouse model . - pubmed
For the first time , we propose a histology - verified method allowing appropriate individual BTV estimation for volumetric in vivo monitoring of tumor growth with [ ( 18 ) F ]- FET PET and show that standardized thresholds from routine clinical practice seem to be inappropriate for BTV estimation in the GBM mouse model . - pubmed
Impact of Time to Appropriate Therapy on Mortality in Patients with Vancomycin - Intermediate Staphylococcus aureus Infection . - pubmed
Despite the increasing incidence of vancomycin - intermediate Staphylococcus aureus ( VISA ) infections , few studies have examined the impact of delay in receipt of appropriate antimicrobial therapy on outcomes in VISA patients . - pubmed
Presence of a VISA infection compared to that of a non - VISA S. - pubmed
Future studies should ( i ) include larger numbers of patients with VISA infections to confirm the findings presented here and ( ii ) determine the optimal antibiotic therapy for critically ill patients with MRSA and VISA infections . - pubmed
METHODS : Adults and children admitted to Chittagong Medical College Hospital with a temperature of & gt;=38.0 C were investigated using a blood smear for malaria , a blood culture , real - time PCR to detect Salmonella Typhi , S. - pubmed
RESULTS : We enrolled 300 febrile patients with a negative malaria smear between January and June 2012 : 156 children ( aged & lt;=15 years ) and 144 adults with a median ( interquartile range ) age of 13 ( 5 - 31 ) years and median ( IQR ) illness duration before admission of five ( 2 - 8) days . - pubmed
Clinical enteric fever was diagnosed in 52 patients ( 17.3 % ) , lower respiratory tract infection in 48 ( 16.0 % ) , non - specific febrile illness in 48 ( 16.0 % ) , a CNS infection in 37 patients ( 12.3 % ) , urinary sepsis in 23 patients ( 7.7 % ) , an upper respiratory tract infection in 21 patients ( 7.0 % ) , and diarrhea or dysentery in 21 patients ( 7.0 % ) . - pubmed
Excessive Cytosolic DNA Fragments as a Potential Trigger of Graves ' Disease : An Encrypted Message Sent by Animal Models . - pubmed
Three - dimensional micro computed tomography analysis of the lung vasculature and differential adipose proteomics in the Sugen / hypoxia rat model of pulmonary arterial hypertension . - pubmed
This study used novel micro computed tomography ( microCT ) three - dimensional modeling to investigate the degree of remodeling of the lung vasculature and differential proteomics to determine small visceral adipose dysfunction in rats with severe PAH . - pubmed
An increased rate of dysphonia was observed among patients undergoing revision surgery ( 25.0 % ) compared to primary surgery ( 1.6 % ) , but stratification by number of levels , gender , and smoking status yielded no differences in complication rates . - pubmed
Assessment of the effects of switching oral bisphosphonates to denosumab or daily teriparatide in patients with rheumatoid arthritis . - pubmed
The aim of this observational , non - randomized study was to clarify the unknown effects of switching oral bisphosphonates ( BPs ) to denosumab ( DMAb ) or daily teriparatide ( TPTD ) in patients with rheumatoid arthritis ( RA ) . - pubmed
Participants preferred HIV oral testing because it was : pain free ( 91 % , n = 399 ) and did not require blood draw ( 82 % , n = 360 ) . - pubmed
Here , we explore pollinator preferences and the genetic architecture of floral divergence using an extensive genetic mapping study in the hybrid zone of two Ipomopsis aggregata subspecies that exhibit a hummingbird and a hawkmoth pollinator syndrome . - pubmed
We included 206 pregnant women with endometriosis : 148 ( 71.8 % ) with endometriosis only , 38 ( 18.4 % ) with focal adenomyosis and 20 ( 9.7 % ) with diffuse adenomyosis . - pubmed
Quantitative monitoring for residual paralysis is advocated as part of routine monitoring with the use of NMBDs for improved patient safety . - pubmed
In the last decade , seizure prediction systems have gained a lot of attention because of their enormous potential to largely improve the quality - of - life of the epileptic patients . - pubmed
Comprehensive epidemiological surveys for Lyme disease have not been conducted for the Bactrian camel in China . - pubmed
Two Borrelia species that cause Lyme disease and one that causes relapsing fever were identified in the camel blood samples by sequencing . - pubmed
The findings of this study indicate that the Bactrian camel may serve as a potential natural host of Lyme disease and/or relapsing fever in China . - pubmed
Predictive value of microRNA let-7a expression for efficacy and prognosis of radiotherapy in patients with lung cancer brain metastasis : A case - control study . - pubmed
This study aims to investigate the value of serum microRNA - let-7a ( miR - let-7a ) expression in predicting efficacy and prognosis of radiotherapy in patients with lung cancer brain metastasis . - pubmed
Later , we found that decreased miR - let-7a displayed an unfavorable role in radiotherapy efficacy and overall survival rate of patients with lung cancer brain metastasis . - pubmed
BACKGROUND : Endotracheal intubation can occur in up to 60 % of critically ill patients . - pubmed
METHODS : A multicenter , observational , prospective study of adult critically ill patients admitted to both medical and surgical intensive care units ( ICUs ) was conducted . - pubmed
A 20 - year - old man submitted to surgical insertion of a lumboperitoneal drain as a treatment for intracranial hypertension , secondary to venous sinus thrombosis , developed severe headache accompanied by nausea , vomiting , and diplopia 24 hours postoperative . - pubmed
Pain relief was immediate , complete , and sustained for about 24 hours ; a second block was performed effectively with pain control , and the patient was discharged . - pubmed
PURPOSE : Venous thromboembolism ( VTE ) is the second most common cause of death in hospitalized patients with cancer , and cancer treatments may exacerbate VTE risk . - pubmed
After carefully compensating spatially dependent dispersion , we achieve delineation of fine outer retinal bands in mouse strains of varying pigmentation . - pubmed
Since 1997 , a yellowing disease has been observed in greenhouse tomato ( Lycopersicon escu - lentum ) . - pubmed
OBJECTIVE : Complete surgical resection of metastatic sites has been shown to prolong survival in select patients with oligometastatic RCC . - pubmed
The objective of this study was to explore the utility of PSMA - targeted 18F - DCFPyL PET / CT in patients with presumed oligometastatic clear cell RCC . - pubmed
In the present analysis , patients with oligometastatic clear cell RCC , defined as & lt;= 3 metastatic lesions on conventional imaging , were evaluated . - pubmed
RESULTS : The final cohort included 14 patients with oligometastatic clear cell RCC . - pubmed
Risk Factors for Major Adverse Cardiovascular Events in Phase III and Long - Term Extension Studies of Tofacitinib in Patients With Rheumatoid Arthritis . - pubmed
This study was undertaken to evaluate the risk of major adverse cardiovascular events ( MACE ) in patients with RA receiving tofacitinib . - pubmed
METHODS : Data were pooled from patients with moderately to severely active RA receiving & gt;=1 tofacitinib dose in 6 phase III and 2 long - term extension studies over 7 years . - pubmed
RESULTS : Fifty - two MACE occurred in 4,076 patients over 12,873 patient - years of exposure ( incidence rate 0.4 patients with events per 100 patient - years ) . - pubmed
Galloyl - Hexahydroxydiphenoyl ( HHDP )- Glucose Isolated From Punica granatum L. Leaves Protects Against Lipopolysaccharide ( LPS)-Induced Acute Lung Injury in BALB / c Mice . - pubmed
In this study , we investigated the therapeutic effects of galloyl - hexahydroxydiphenoyl ( HHDP )- glucose isolated from pomegranate leaves on lipopolysaccharide ( LPS)-induced acute lung injury ( ALI ) in mice . - pubmed
In addition , the ALI mice treated with galloyl - HHDP - glucose also presented reduced lung inflammatory cell accumulation , especially that of neutrophils , in their BALF and lungs . - pubmed
Effect of verbal and written information on pain perception in patients undergoing fixed orthodontic treatment : a randomized controlled trial . - pubmed
BACKGROUND : Pain can discourage patients from seeking orthodontic treatment or compromise their compliance during therapy . - pubmed
Thirty - eight patients with AIS undergoing Cheneau - type bracing were included . - pubmed
Furthermore , investigation on the mechanisms underpinning the morphological and behavioral traits associated with canid domestication syndrome is of significance not only for scientific study but also for human medical research . - pubmed
Comparative Pro - cognitive and Neurochemical Profiles of Glycine Modulatory Site Agonists and Glycine Reuptake Inhibitors in the Rat : Potential Relevance to Cognitive Dysfunction and Its Management . - pubmed
and D - cycloserine ( 2.5 - 40 mg / kg ) that all dose - dependently prevented scopolamine disruption of social recognition in adult rats . - pubmed
Finally , in rats socially isolated from weaning ( a neurodevelopmental model of schizophrenia ) , S18841 ( 2.5 and 10 mg / kg s.c . ) - pubmed
In conclusion , despite contrasting neurochemical profiles , partial glycine site agonists and glycine reuptake inhibitors exhibit comparable pro - cognitive effects in rats of potential relevance to treatment of schizophrenia and other brain disorders where cognitive performance is impaired . - pubmed
Diversity of bacteriophages encoding Panton - Valentine leukocidin in temporally and geographically related Staphylococcus aureus . - pubmed
aureus strains that cause serious infections and clones of community - associated methicillin - resistant S. - pubmed
Methods : A retrospective analysis was conducted on the clinical data of 16 patients with the low distal humerus fracture between January 2016 and January 2018 at Department of Orthopaedics , Shanghai Tongji Hospital Affiliated to Tongji University . - pubmed
Conclusion : Laparoscopic rectopexy is a safe minimally invasive approach for children with idiopathic RP that offers high patient satisfaction with same - day discharge , early recovery , and low recurrence . - pubmed
Estimating daytime sleepiness with previous night EEG , EOG and EMG spectrograms in patients with suspected sleep apnea using a convolutional neural network . - pubmed
We trained a convolutional neural network ( CNN ) classifier using electroencephalography , electrooculography , and chin electromyography signals from 2014 patients with suspected OSA . - pubmed
The CNN was trained to classify the patients into four sleepiness categories based on their mean sleep latency ( MSL ) ; severe ( MSL<5min ) , moderate ( 5<=MSL<10 ) , mild ( 10<=MSL<15 ) and normal ( MSL>=15 ) . - pubmed
Results : A convenience sample of 74 children , aged 9 - 68 months ( mean : 32.45 , SD : 14.08 ) with mobility limitations , and their parents participated . - pubmed
In the present study , we investigated the protective effects of piperine against mastitis using a mouse mastitis model . - pubmed
Procoagulant Disorders in Patients with Newly Diagnosed Pancreatic Adenocarcinoma . - pubmed
Analyzed patients were hospitalized in the Department of Digestive Tract Diseases , Medical University of Lodz or in the Department of Digestive Tract Surgery , Silesian University , Katowice , Poland . - pubmed
Conclusions : The coagulation disorders are present in the majority of patients with pancreatic adenocarcinoma already at the diagnosis stage and reflect cancer progression and spread . - pubmed
METHODS : 90 patients with acute uncomplicated appendicitis who underwent emergency open appendectomy from December 2017 to August 2018 were included in this prospective study . - pubmed
Results : Perceived accuracy of health misinformation was strongly correlated across statins , cancer , and the HPV vaccine ( rs > = .70 ) , indicating that individuals who are susceptible to misinformation about one of these topics are very likely to believe misinformation about the other topics as well . - pubmed
The effects of pyridostigmine pretreatment on the neuromuscular blockade produced by soman in anaesthetized , atropinized animals have been studied on the soleus and anterior tibialis muscle ( rhesus monkeys , cats and rabbits ) and the gastrocnemius muscle ( guinea - pigs and rats ) . - pubmed
A new test showing abnormal net Na+ and K + fluxes in erythrocytes of essential hypertensive patients . - pubmed
A new and simple laboratory test for measuring net Na + and K + fluxes in Na +-loaded / K +-depleted human erythrocytes was developed and applied to hypertension . - pubmed
The ratio of Na+/K+ net fluxes was therefore reduced in all essential hypertensive patients . - pubmed
Conversely , Na + and K+ erythrocyte fluxes were normal in hypertension of renal origin ( 5 patients ) . - pubmed
[ Ambulatory rehabilitation of myocardial infarct patients . - pubmed
Streptococcus faecalis , while the most common streptococcal serotype causing urinary tract infection , is not the only one . - pubmed
Reduction of hypoxic pulmonary vasoconstriction during diethyl ether anaesthesia in the dog . - pubmed
Corticosteroid production by the human foetus : evidence from analysis of urine from women pregnant with a normal or an anencephalic foetus . - pubmed
We performed MR studies of 16 patients with head and neck tumors with detailed clinical , surgical , and pathologic information . - pubmed
The data indicated that the function of T helper cells in patients with TB was impaired , and the impairment was more serious in the patients with longer illness . - pubmed
Energy expenditure and substrate oxidation in patients with cirrhosis : the impact of cause , clinical staging and nutritional state . - pubmed
This article is about resting energy expenditure and substrate oxidation rates in 123 patients with biopsy - proven cirrhosis differing with respect to cause , duration of the disease , biochemical parameters of parenchymal cell damage , cholestasis , liver function , number of complications , clinical staging and nutritional state . - pubmed
Lipid oxidation was increased , but glucose oxidation was reduced in nearly all patients with cirrhosis . - pubmed
It may cause malnutrition and contributes to the clinical outcome of patients with chronic liver disease . - pubmed
The eight patients were selected because they had low anticapsular antibody responses to Hib disease . - pubmed
Only one of the eight children had a history of previous severe , recurrent infections . - pubmed
A case of Bence Jones kappa multiple myeloma with meningeal involvement in a 64 - year - old woman is presented . - pubmed
Exertional headaches in patients with Arnold - Chiari malformation ( ACM ) are well described . - pubmed
We report four patients with Type I ACM and recurrent headaches . - pubmed
These patients presented , respectively , with low spinal fluid pressure headache , migraine without aura , migraine with aura , and migraine with prolonged aura . - pubmed
This report suggests the need for observing patients with recurrent headaches for any physical stigmata of craniovertebral junction anomalies , and the need to exclude ACM in such patients . - pubmed
Fifty - six patients with traumatic and 117 patients with inflammatory lesions of the knee and ankle were examined with a 2 T ( 69 examinations ) or 0.23 T ( 104 examinations ) MR system . - pubmed
In patients with traumatic and inflammatory diseases of the knee and ankle , high field imaging at 2 T provided better image quality than low field imaging at 0.23 T. - pubmed
A retrospective study was done on 30 patients who underwent surgical correction of the penile deformity secondary to Peyronie ' s disease between 1983 and 1988 . - pubmed
Over - all , 19 patients ( 63 % ) improved postoperatively , which implied erection free of pain with minimal or no deformity and the ability to perform normal sexual intercourse . - pubmed
We recommend this procedure for patients in whom surgical correction of the deformity is indicated . - pubmed
Additionally , response following ifosfamide treatment is being evaluated for previously untreated children with osteosarcoma and rhabdomyosarcoma after 6 weeks of treatment , and for previously untreated patients with Ewing ' s sarcoma after 9 weeks of treatment with ifosfamide / VP-16 ( etoposide ) given in combination . - pubmed
Treatment of depressed tinnitus patients with nortriptyline . - pubmed
Patients disabled by tinnitus show a high prevalence of major depression . - pubmed
To explore further this link between tinnitus and depression , and to investigate the efficacy of treating depression in the treatment of tinnitus , a single - blind , placebo - washout , nonrandomized pilot study of the tricyclic antidepressant nortriptyline ( hydrochloride ) was undertaken in disabled tinnitus patients who also met diagnostic criteria for major depression . - pubmed
Sodium sensitivity in normotensive and borderline hypertensive humans . - pubmed
The responses to sodium depletion and repletion were studied in subgroups of 92 normotensive and 65 borderline hypertensive individuals . - pubmed
Maternal - paternal toxicity ( body weight evolution , feather coat ) and tolerance in newborn pigeons ( general behaviour , daily gain in body weight , feathering , skeletal anomalies ) were also evaluated . - pubmed
Hatched pigeons showed a satisfactory daily weight gain and deaths among these birds were exceptional . - pubmed
A potential animal model for autoimmune reproductive failure . - pubmed
Eighty - eight patients have been successfully treated endoscopically without complications using contact neodymium yttrium aluminum garnet : ( YAG ) laser probes ( endoprobes ) for tumors and bleeding and during open surgery ( laser scalpel ) to perform hepatic and pancreatic resections . - pubmed
Two hundred seventy ( 270 ) consecutive surgical patients treated at Roswell Park Memorial Institute for carcinoma of the oral cavity , oropharynx , hypopharynx , and larynx between 1977 and 1982 were reviewed to determine the relationship between pathological findings at the surgical margins of the primary tumor and the incidence of local recurrence and clinical outcome . - pubmed
The estimated 5 - year disease - free survival rate was 39 % for patients with free surgical margins ( 10%--hypopharynx , 30%--oropharynx , 40%--oral cavity , and 53%--larynx ) and 7 % for not - free surgical margins . - pubmed
Patients with free surgical margins and with well - differentiated squamous cell carcinoma had better prognosis than those patients with moderately- and poorly - differentiated carcinomas . - pubmed
The extent of stress - protection was investigated in 12 patients with previous tibial fractures treated by steel plate fixation . - pubmed
Subgaleal hematoma in a child , without skull fracture . - pubmed
[ ATP and 2,3 - DPG concentrations in the erythrocytes of peritonitis patients ] . - pubmed
[ Independence of neurogenic atrophy and alloxan diabetic atrophy in their effects on the transport of phosphate ion in the gastronemus of the rat ] . - pubmed
We speculate that the somewhat surprising similarity between the ecology of the mouse large intestine and that of a CF culture in a glass vessel is due to the fact that both are dominated by thick layers of complex bacterial flora , the composition of which is controlled by their metabolic activities and by their relative ability to adhere to each other . - pubmed
Although patients with bronchiolitis elicited similar levels of the activity until the first week , the response was significantly suppressed during the subsequent two weeks . - pubmed
The response at the second week in this group was significantly lower than those of corresponding specimens obtained from patients with pneumonia ( p less than 0.01 ) or tracheobronchitis ( p less than 0.05 ) , suggesting a close association of the responsiveness with underlying mechanisms of bronchiolitis induced by RSV . - pubmed
Chronic experiments on cats were carried out to study the effect of haloperidol and clozapine on the pattern of contralateral rotations produced by electric stimulation of the caudate nucleus . - pubmed
Malignancy and anchorage independence of Djungarian hamster tumor cell lines resistant to different doses ( 0.1 - 5.0 micrograms / ml ) of colchicine were studied . - pubmed
Variation of the arteria profunda femoris in man . - pubmed
Signs of peritoneal irritation were present in all patients , including the 16 children receiving corticosteroid therapy . - pubmed
There is weak evidence that SPECT is useful in : ( a ) detecting pseudarthroses after failed spinal fusion , ( b ) evaluating young patients with back pain and ( c ) distinguishing benign from malignant lesions in cancer patients . - pubmed
CONCLUSION : The decision to use SPECT in most patients with low back pain can not be supported by clinical trials . - pubmed
Similarly , five - year disease - free survival in 17 patients with Dukes B and C cancers who had curative resections did not differ between the groups ( log rank test : chi - squared = 0.08 ; P & gt ; 0.25 ) . - pubmed
To ascertain the clinical value in gynecologic cancers , the authors studied 612 nonpregnant women . - pubmed
Thus , gamma 2b H chains : 1 ) can act alone to promote the development of mature B cells , 2 ) synergize with microH chains for allelic exclusion , and 3 ) vary in their influence on B cell development in different transgenic mouse strains . - pubmed
The safety study primarily demonstrated drowsiness in one - fourth of the patients receiving placebo and active treatment . - pubmed
Protection against alloxan - induced diabetes by diethyldithiocarbamate and disulfiram in mice . - pubmed
Fasted mice did not exhibit hyperglycemia at 0.5 hr after DEDC injection , and alloxan given at that time produced diabetes . - pubmed
These findings indicate that DEDC itself protected mice from alloxan - induced diabetes by the indirect mechanism of producing hyperglycemia at the time of alloxan administration . - pubmed
The anti - diabetogenic action of low doses of DS and DEDC , in animals lacking hyperglycemia at the time of alloxan injection , is likely based on a mechanism other than one involving hyperglycemia . - pubmed
The ease of isolation , growth , and transfection of primary mouse myoblasts under the conditions described here expand the opportunities to study muscle cell growth and differentiation using myoblasts from normal as well as mutant strains of mice . - pubmed
The properties of these cells after transplantation -- the stability of resulting hybrid myofibers without immune suppression , the persistence of transgene expression , and the lack of tumorigenicity -- suggest that studies of cell - mediated gene therapy using primary myoblasts can now be broadly applied to mouse models of human muscle and non - muscle diseases . - pubmed
Characterization of twenty - six new heat shock genes of Escherichia coli . - pubmed
Here we report the characterization of 26 new heat shock genes of E. - pubmed
A 63 - year - old man with multiple nodules and pathological findings of acantholysis is reported as a case of warty dyskeratoma presenting with multiple lesions . - pubmed
The binding activity of 2 of the CDDP - damage - recognition proteins , of relative molecular mass 48 and 97 kDa , is greater in a CDDP - resistant human ovarian tumour cell line than in the parental sensitive line . - pubmed
The relation between left - ventricular stroke volume ( SV ) and end - diastolic volume ( EDV ) was determined based on angiocardiographic measurements in 10 open - chest minipigs under varying filling conditions ( blood letting or infusions ) . - pubmed
Twenty three patients suffered from renal vasculitis , most commonly Wegener ' s granulomatosis ( 14 patients ) and microscopic polyarthritis ( 7 patients ) . - pubmed
IgA nephropathy ( 7 patients ) and idiopathic necrotizing / crescentic glomerulonephritis ( 8 patients ) prevailed in patients with limited renal involvement . - pubmed
Renal morphology and function was most seriously impaired in patients with Wegener ' s granulomatosis . - pubmed
Clinical signs of extrarenal involvement are present in about 50 % of patients with ANCA - positive glomerulonephritis . - pubmed
IMPLICATIONS FOR NURSING PRACTICE : Nurses can play a major role in the supportive care of patients with anemia through interventions related to pharmacological therapy , blood transfusions , nutritional counseling , and symptom management . - pubmed
BACKGROUND : The addition of droperidol to morphine for patient - controlled analgesia reduces the incidence of nausea and vomiting , but may result in unwanted side effects . - pubmed
Subjective drowsiness which resulted in withdrawal from the study occurred in two patients , both of whom were receiving droperidol , and though all patients who completed the study were satisfied with their analgesia overall , significantly more of those receiving unsupplemented morphine ( 11/19 compared with 4/18 , P & lt ; 0.05 ) described it as excellent . - pubmed
Injection of zymosan - activated plasma into the rat paw induced oedema formation . - pubmed
A new heart failure model in rat by an end - to - side femoral vessel anastomosis . - pubmed
OBJECTIVE : The aim of this study was to develop a new shunting procedure for producing heart failure in the rat incorporating microvascular techniques and avoiding an abdominal operation . - pubmed
CONCLUSION : This model provides a relatively simple and reproducible means of creating high output heart failure and cardiac hypertrophy in the rat without necessitating abdominal surgery . - pubmed
METHODS AND RESULTS : We recorded peroneal muscle sympathetic nerve activity in 17 treated heart failure patients ( 16 men,1 woman ; mean ejection fraction of 26 . - pubmed
The role of the ixodid tick Hyalomma lusitanicum Koch 1844 as a vector of Mediterranean or tropical theileriosis ( caused by the protozoan parasite Theileria annulata Dschunkowsky et Luhs 1904 ) in southern Spain was studied . - pubmed
annulata - infected cattle from the theileriosis enzootic area studied ( province of Cadiz , southern Spain ) . - pubmed
Likewise , we found that all sera of the cattle previously considered as suspected of theileriosis by clinical signs , tested for T. - pubmed
annulata - infected cattle in this enzootic area and fed on an uninfected calf in an experimental farm free of theileriosis and ticks . - pubmed
Five per cent of patients with germ cell tumours of the testis will develop a further tumour in the contralateral testis . - pubmed
Efficacy of implantable cardioverter - defibrillators for the prevention of sudden death in patients with hypertrophic cardiomyopathy . - pubmed
BACKGROUND : Hypertrophic cardiomyopathy is a genetic disease associated with a risk of ventricular tachyarrhythmias and sudden death , especially in young patients . - pubmed
METHODS : We conducted a retrospective multicenter study of the efficacy of implantable cardioverter - defibrillators in preventing sudden death in 128 patients with hypertrophic cardiomyopathy who were judged to be at high risk for sudden death . - pubmed
In the group of 43 patients who received defibrillators for secondary prevention ( after cardiac arrest or sustained ventricular tachycardia ) , the devices were activated appropriately in 19 patients ( 11 percent per year ) . - pubmed
In all 21 patients with stored electrographic data and appropriate interventions , the interventions were triggered by ventricular tachycardia or fibrillation . - pubmed
CONCLUSIONS : Ventricular tachycardia or fibrillation appears to be the principal mechanism of sudden death in patients with hypertrophic cardiomyopathy . - pubmed
In high - risk patients with hypertrophic cardiomyopathy , implantable defibrillators are highly effective in terminating such arrhythmias , indicating that these devices have a role in the primary and secondary prevention of sudden death . - pubmed
Enteropathy - type intestinal T - cell lymphoma : clinical features and treatment of 31 patients in a single center . - pubmed
PURPOSE : We report the clinical features and treatment of 31 patients with a diagnosis of enteropathy - type intestinal T - cell lymphoma treated at the Wessex Regional Medical Oncology Unit in Southampton between 1979 and 1996 ( 23 men , eight women ) . - pubmed
PATIENTS AND METHODS : Patients were identified from our lymphoma database . - pubmed
RESULTS : Twelve patients ( 35 % ) had a documented clinical history of adult - onset celiac disease , and a further three had histologic features consistent with celiac disease in resected areas of the small bowel not infiltrated with lymphoma . - pubmed
Infection of Bergmann glia in the cerebellum of a skunk experimentally infected with street rabies virus . - pubmed
Rabies virus is a highly neuronotropic virus and glial cell infection is not prominent in the central nervous system ( CNS ) . - pubmed
Paraffin - embedded tissues from the cerebella of skunks experimentally infected with either a skunk salivary gland isolate of street rabies virus or the challenge virus standard ( CVS ) strain of fixed rabies virus were examined with immunoperoxidase staining for rabies virus antigen by using an anti - rabies virus nucleocapsid protein monoclonal antibody . - pubmed
A skunk infected with street rabies virus showed prominent infection of Bergmann glia . - pubmed
These findings indicate that although rabies virus is a highly neuronotropic virus , street rabies virus strains do not always demonstrate strict neuronotropism in the central nervous system . - pubmed
The patients suffered from stenoses ( n = 6 ) , occlusions ( n = 7 ) , aneurysms , ( n = 2 ) or acute hemorrhage ( n = 2 ) . - pubmed
In 4 Patients of the stenosis - group re - stenosis occurred and following stent - implantation one occlusion after 6 months was observed . - pubmed
Exposure to ionizing radiation in children undergoing Amplatzer device placement to close atrial septal defects . - pubmed
Between June 1998 and April 1999 , dosimetry was carried out on 12 patients with Amplatzer device occlusion of atrial septal defects ( n = 10 ) or Fontan fenestration ( n =) and 12 age - matched patients who underwent diagnostic catherization . - pubmed
Dietary restriction ( DR ) increases the lifespan of rodents and increases their resistance to several different age - related diseases including cancer and diabetes . - pubmed
OBJECTIVE : To evaluate the effects of mechanical compression of the brain - stem in patients with vertebrobasilar dolichoectasia ( VBD ) . - pubmed
METHODS : In the framework of a prospective , observational study that collected clinical and laboratory data in patients with VBD , we studied 20 patients with compression of the brain - stem due to ectatic , tortuous basilar or vertebral arteries . - pubmed
Patients with cerebral lesions other than small lacunae in the white matter of the cerebral hemispheres were excluded from the study . - pubmed
RESULTS : Almost all of the patients complained of auditory or vestibular symptoms and none had symptoms or signs of impairment of long tracts or the facial and trigeminal nerves . - pubmed
Functional investigations may be useful in the long - term management of these patients , since VBD may be progressive and surgical correction may be required at some stage . - pubmed
To define genes associated with the pigmentary disorder vitiligo , gene expression was compared in non - lesional melanocytes cultured from three vitiligo patients and from three control melanocyte cultures by differential display . - pubmed
RNH-6270 did not affect serum - stimulated DNA synthesis in VSMCs from both rat strains . - pubmed
RNH-6270 abolished angiotensin II - stimulated DNA synthesis in VSMC from both rat strains . - pubmed
OBJECTIVE : Using three - dimensional computed tomography , we investigated the morphologic deformity of the birth canal in patients with developmental dysplasia of the hip who underwent dome pelvic osteotomy . - pubmed
STUDY DESIGN : Thirty - five normal subjects , 34 patients with developmental dysplasia of the hip who did not undergo dome pelvic osteotomy , and 21 patients with developmental dysplasia of the hip who underwent dome pelvic osteotomy were recruited for the study . - pubmed
CONCLUSION : Anthropoid - type pelvis ( a long pelvic inlet diameter in the sagittal dimension while the corresponding measurement in the transverse dimension is short ) was observed in as many as 90.5 % of patients with developmental dysplasia of the hip after dome pelvic osteotomy . - pubmed
MATERIALS AND METHODS : Seven healthy adult volunteers with no history of neurologic disease or head trauma were recruited and gave their informed consent . - pubmed
Mechanisms of ocular toxicity using the in vitro bovine lens and sodium dodecyl sulfate as a chemical model . - pubmed
Although parasite clearance times were shorter in the quinine - rifampin - treated patients ( mean + /- standard deviation , 70 + /- 21 versus 82 + /- 18 h ; P = 0.023 ) , recrudescence rates were five times higher ( n = 15 of 23 ; 65 % ) than those obtained with quinine alone ( n = 3 of 25 ; 12 % ) , P & lt ; 0.001 . - pubmed
Rifampin should not be combined with quinine for the treatment of malaria , and the doses of quinine should probably be increased in patients who are already receiving rifampin treatment . - pubmed
The carotid IMT was measured by B - mode ultrasonography in type 2 diabetic patients . - pubmed
Acetate metabolism in isolated epididymal adipost tissue from obese - hyperglycemic mice of different ages . - pubmed
Influence of p - hydroxy - propiophenone on liver tumorigenesis in rats ingesting ethionine and N-2 - fluorenylacetamide . - pubmed
[ Ascites and reversible experimental edema in dogs researches on the role of nutrition , portal pressure and antidiuretic factors ] . - pubmed
OBJECTIVE : The purpose of this study was to establish selection criteria for intentional limited resection in patients with peripheral lung cancer . - pubmed
RESULTS : The positive rate of invasive factors was 30.8 % among the patients with tumors 2 cm or less in diameter , and significantly lower than the 44.0 % noted in those whose tumor diameter was in the 2.1 - 3.0 cm range . - pubmed
The positive rate was significantly lower in 90 patients with type A or B adenocarcinoma , and none of these patients developed postoperative recurrence . - pubmed
In 24 of these 90 patients , the tumor diameter was in the 2.1 - 3.0 cm range . - pubmed
The 5 - year survival rate in the 74 patients with pT1N0M0 and tumors 2 cm or less in diameter who underwent limited resection was 89.1 % . - pubmed
Anti - inflammatory effect of methoxyphenamine compound in rat model of chronic obstructive pulmonary disease . - pubmed
METHODS : Adult rat model of COPD ( COPD group ) was induced by intratracheal instillation of lipopolysaccharides and exposure to cigarette smoke . - pubmed
CONCLUSION : MC has anti - inflammmatory effect in the rats with COPD . - pubmed
STUDY OBJECTIVES : Recently , we demonstrated significantly improved baroreflex sensitivity ( BRS ) and autonomic balance after 31 % supplemental oxygen ( SuppO2 ) in resting patients with chronic obstructive pulmonary disease ( COPD ) . - pubmed
PARTICIPANTS : Seventy subjects with moderate to severe COPD . - pubmed
BRS was derived using the sequence method before and after treatments with compressed air ( CA ) and 30 % SuppO2 in 70 individuals with COPD via a counterbalanced crossover design . - pubmed
Cerebral edema is the primary cause of morbidity and mortality in children and adolescents with diabetic ketoacidosis ( DKA ) . - pubmed
We report a case of an adolescent female with life - threatening DKA - related cerebral edema who responded to a combination of mannitol and hypertonic saline . - pubmed
In some animals the liver was sampled and showed periportal fibrosis , bile duct proliferation and sometimes necrosis . - pubmed
METHODS AND RESULTS : A retrospective observational study of 126 patients with a ST - segment elevation myocardial infarction ( STEMI ) ; 101 patients had reperfusion therapy ( 93 thrombolysis , 8 PTCA ) . - pubmed
This article summarizes our current understanding of ischemic heart disease and heart failure in patients with diabetes mellitus , highlighting gaps in our knowledge about the relationship between diabetes and cardiovascular disease . - pubmed
MATERIAL AND METHODS : We performed a metaanalysis to combine the results of the studies which compared the frequency of depression in MS patients with the prevalence in patients with other chronic diseases . - pubmed
Treatment of stroke in adult mice with atorvastatin daily for 14 days , starting at 24 hours after MCAO , shows significant improvement in functional recovery compared with control animals . - pubmed
The medical records of patients with high - grade osteosarcoma observed at the authors ' institution between 1972 and 1999 were reviewed to study whether osteosarcoma in preadolescent patients has a different biology and a worse prognosis than in older patients . - pubmed
In the second analysis , only 1,136 patients ( 317 preadolescent and 819 older patients ) with nonmetastatic extremity osteosarcoma , treated with the same protocols of chemotherapy , were evaluated to assess differences in prognosis and in the pattern of relapse . - pubmed
Most preadolescents were female ( 56 % vs. 44 % , P & lt ; 0.0001 ) , and most tumors were located in the extremity ( 95 % vs. 5 % , P & lt ; 0.001 ) . - pubmed
To compare the systemic oxidant - antioxidant status in patients with acute exacerbations and stable asthma , we measured a wide range of parameters of oxidant - antioxidant balance in leukocytes , plasma , and red cells of 32 patients with acute exacerbations and 97 patients with stable asthma . - pubmed
For patients with advanced non - small cell lung cancer ( NSCLC ) , chemotherapy , alone or in combination with radiation therapy , is considered the standard treatment . - pubmed
Goals of molecular targeted therapy studies include the following : better understanding of the exact role of particular growth factors in specific tumors ; establishment of new clinical study designs for biological agents ; and tailoring appropriate combinations of conventional chemotherapy and/or radiotherapy with biological therapy for specific patients . - pubmed
Achievement of these goals will hopefully lead to incorporation of biological therapy into the current anticancer arsenal , for the benefit of lung cancer patients . - pubmed
The promoter and reporter were co - transfected into a human prostate cancer cell line PC3 - M with the aid of Lipofectamin 2000 . - pubmed
The Vibrio cholerae bacterium causes devastating diarrhea when it infects the human intestine . - pubmed
In 1986 - 2003 yrs the interventions for cancer of the operated stomach were performed in 32 patients . - pubmed
Evaluation of diagnostic tests and argatroban or lepirudin therapy in patients with suspected heparin - induced thrombocytopenia . - pubmed
STUDY OBJECTIVES : To evaluate diagnostic tests for heparin - induced thrombocytopenia ( HIT ) , a serious drug reaction that can occur in patients receiving heparin , and to evaluate treatment with direct thrombin inhibitors - the only initial drug therapy that decreases the risk of thromboembolism associated with immune - mediated HIT . - pubmed
SUBJECTS : Patients with HIT treated with argatroban or lepirudin between January 1 , 2000 , and December 31 , 2003 . - pubmed
MEASUREMENTS AND MAIN RESULTS : Patients were assessed for dosage and duration of argatroban or lepirudin therapy , HIT diagnostic tests , and clinically significant adverse events . - pubmed
Although platelet - aggregation tests were ordered in 55 ( 72 % ) of 76 patients , they were not useful in 16 ( 29 % ) because of equivocal or contradictory results . - pubmed
OBJECT : Adenovirus vector ( AdV)-mediated gene delivery has been recently demonstrated in clinical trials as a novel potential treatment for malignant gliomas . - pubmed
Severe liver injury after initiating therapy with atomoxetine in two children . - pubmed
Two children presented with acute hepatitis after starting therapy with atomoxetine ( Strattera ) . - pubmed
In one child , no competing diagnosis could be identified , and liver injury resolved completely on withdrawal of the medication . - pubmed
In the second child , the evaluation was suggestive of type 1 autoimmune hepatitis ; she subsequently improved with removal of atomoxetine and concomitant immunosuppressive therapy . - pubmed
METHODS : The weight changes of 228 children with obesity were evaluated according to frequency of child and parental self - monitoring . - pubmed
Long - term high - fat diet induces pancreatic injuries via pancreatic microcirculatory disturbances and oxidative stress in rats with hyperlipidemia . - pubmed
The objective of this study was to induce hyperlipidemia in rats by long - term high - fat diet intake , then investigate the biochemical , microcirculatory , and histological alterations in blood and pancreatic tissues of these animals , and discuss their potential significances . - pubmed
The results showed that the velocity of pancreatic microvascular blood flow of rats with hyperlipidemia decreased significantly as compared to control value ( p = 0.008 ) . - pubmed
Eighty subjects ( 41 male ) were assigned to one of four groups ( 24 - h deprived or nondeprived dependent smokers , occasional smokers , and nonsmokers ) and participated in an instructed fear conditioning paradigm involving cued administration of electric shock . - pubmed
There were also areas of human immunodeficiency virus ( HIV ) knowledge that were lacking . - pubmed
Most patients listed the media as their main source of knowledge about STI and HIV . - pubmed
BACKGROUND : Actinic keratoses ( AKs ) are the most common epithelial precancerous lesions , especially among individuals with light complexions . - pubmed
Patients with grade 3 ( very thick and/or hyperkeratotic ) lesions were excluded . - pubmed
The demographics of this study population are typical of a patient population with AK . - pubmed
METHODS : SC and OM adipose tissues were obtained from 10 obese and 11 nonobese NAFLD patients and from 11 obese and 13 nonobese patients without NAFLD , who served as controls . - pubmed
In this setting , switching strategies may be useful to minimize clinical and psychological consequences , improving the quality of life of HIV - infected patients treated with HAART . - pubmed
OBJECTIVE : Uveitis occurs in 10%-15 % of patients with juvenile idiopathic arthritis ( JIA ) . - pubmed
Neurotoxicosis in 4 cats receiving ronidazole . - pubmed
OBJECTIVE : To collect information on clinical practice and current management strategies in 22 Italian neurosurgical hospitals for patients with aneurysmal subarachnoid hemorrhage . - pubmed
PATIENTS : 350 cases of aneurysmal subarachnoid hemorrhage . - pubmed
Neurological deterioration ( 24 % ) was more frequent in patients with higher Fisher classification , and with pretreatment rebleeding and it was associated with an unfavorable outcome ( 46 % , 36/78 , vs. 33 % , 83/251 ) . - pubmed
Intracranial hypertension was experienced in one - third of the patients , followed by hydrocephalus ( 29 % ) and vasospasm ( 30 % ) . - pubmed
Infection of the thyroid gland caused by Campylobacter fetus subsp . - pubmed
We report what we consider to be the first case of an abscess of the thyroid gland due to Campylobacter fetus subsp . - pubmed
fetus is known as a rare and opportunistic pathogen in humans , causing a broad variety of systemic infections . - pubmed
It is therefore not unlikely that human infections caused by C. - pubmed
METHODS : Patients with mild pancreatitis were randomized to a CLD or LFSD when they were ready to resume oral nutrition . - pubmed
RESULTS : We randomized 121 patients : 66 to CLD and 55 to LFSD . - pubmed
RATIONALE : Patients with refractory asthma have persistent symptoms despite maximal treatment with inhaled corticosteroids and long - acting bronchodilators . - pubmed
OBJECTIVES : To determine the efficacy of clarithromycin in patients with severe refractory asthma and specifically in a subgroup of patients with noneosinophilic asthma . - pubmed
METHODS : Subjects with severe refractory asthma ( n = 45 ) were randomized to receive clarithromycin ( 500 mg twice daily ) or placebo for 8 weeks . - pubmed
A primate poxvirus ( OrTeCa ) isolated from a skin lesion in a rhesus monkey ( Macaca mulatta ) was studied along with four known poxviruses : vaccinia , monkeypox , swinepox , and Yaba . - pubmed
It grows in established lines of monkey kidney cells at a rate intermediate between that of vaccinia and monkeypox and that of swinepox and Yaba . - pubmed
Neither can OrTeCa be grown in rabbit kidney or chick embryo cells or on chick chorioallantoic membranes , all of which support the growth of vaccinia and monkeypox viruses . - pubmed
OrTeCa forms plaques about the same size as those of Yaba and swinepox viruses , but they appear earlier ; they are morphologically similar to the plaques of vaccinia and monkeypox viruses . - pubmed
The thermal stability of OrTeCa is about the same as that of vaccinia and monkeypox but greater than that of Yaba virus . - pubmed
We have previously demonstrated that apigenin , a plant flavone , causes decreased survival in human prostate cancer cells . - pubmed
Efficacy and safety of oral fumarate in patients with relapsing - remitting multiple sclerosis : a multicentre , randomised , double - blind , placebo - controlled phase IIb study . - pubmed
Our aim was to assess the efficacy and safety of BG00012 in patients with relapsing - remitting multiple sclerosis . - pubmed
METHODS : 257 patients , aged 18 - 55 years , with relapsing - remitting multiple sclerosis were randomly assigned to receive 120 mg once daily ( n=64 ) , 120 mg three times daily ( n=64 ) , or 240 mg three times daily ( n=64 ) BG00012 , or placebo ( n=65 ) for 24 weeks . - pubmed
Adverse events more common in patients given BG00012 than in those given placebo included abdominal pain , flushing , and hot flush . - pubmed
Dose - related adverse events in patients on BG00012 were headache , fatigue , and feeling hot . - pubmed
Simulation of an early warning system using sentinel birds to detect a change of a low pathogenic avian influenza virus ( LPAIV ) to high pathogenic avian influenza virus ( HPAIV ) . - pubmed
The placement of sentinel birds in a commercial poultry flock infected with low pathogenic avian influenza virus ( LPAIV ) may be an effective way of detecting subsequent change in the isolate to a high pathogenic avian influenza virus ( HPAIV ) . - pubmed
These findings may be used by decision makers to evaluate the risk of not depopulating a flock infected with a H5 or H7 LPAIV strain and the benefit of using sentinel birds as an early warning system of a change to HPAIV . - pubmed
Exaggerated pressor responses to mental stress in patients with coronary artery disease ( CAD ) are associated with increased risk for subsequent cardiovascular events . - pubmed
Eighteen healthy individuals ( aged 61 + /- 8 yr ) and 29 individuals with documented CAD but no other comorbidities ( aged 59 + /- 8 yr ) were studied . - pubmed
Characterization of surgical procedures in patients with mucopolysaccharidosis type I : findings from the MPS I Registry . - pubmed
OBJECTIVE : To clarify the extent and chronology of surgical burden in relation to symptom onset and diagnosis in patients with mucopolysaccharidosis I ( MPS I ) as reported in the MPS I Registry , an international observational database . - pubmed
CONCLUSIONS : Pediatricians and pediatric surgeons need to be aware of the surgical burden of MPS I and be alert to its presenting signs and symptoms in children scheduled for surgery . - pubmed
Our objective was to investigate the role of this gene in a large cohort of PD patients and controls . - pubmed
Tuberculins from the avian , bovine and human types of tubercle bacillus as well as " tuberculin " prepared from the Duval and from the Kedrowsky strains of M. - pubmed
RESULTS : All mice exhibited atherosclerotic lesions in the aortic sinus and aortic surface . - pubmed
We further examined the effects of CCR7 deficiency on the inflammatory response to P. - pubmed
METHODS : Membranes from eight patients with active proliferative diabetic retinopathy and nine patients with inactive proliferative diabetic retinopathy were studied by immunohistochemistry . - pubmed
BACKGROUND : Evaluation of hemostasis in bleeding patients requires both accuracy and speed . - pubmed
To assess the ability of this MRI probe as a pH - triggered agent , we utilize a disease rat model of cerebral ischemia that produces acidic tissue due to its pathologic condition . - pubmed
Indacaterol is a novel once - daily ultra - long - acting beta(2)-agonist bronchodilator now approved in the European Union for maintenance bronchodilator treatment of airflow obstruction in adult patients with COPD , to be administered as 150 or 300 microg once - daily dose by means of a single - dose dry powder inhaler . - pubmed
We present the case of an 80 years old man , with upper gastrointestinal bleeding who developed a black esophagus after hypotensive episodes . - pubmed
In the present report we describe the clinical , endoscopic and histophatological characteristics of a patient with a diagnosis of AEN . - pubmed
[ Effects of severe frostbite under hypoxia on some parameters of blood coagulation system in rabbits ] . - pubmed
Circadian rhythms regulate various functions of human body , and the disruption of circadian rhythm has been associated with cancer development and tumor progression . - pubmed
Partial daily pattern gene expression recoveries were observed in patients with CML with complete cytogenetic response and major molecular response . - pubmed
METHODS : Consecutive patients diagnosed with refractory benign stricture of gastrointestinal tract following Kochman 's criteria were included . - pubmed
At the end of follow - up ( median follow - up 30 weeks for esophageal stricture , 33 weeks for rectal stricture ) 5 patients remained asymptomatic . - pubmed
Eighty per cent of patients with esophageal stenosis showed partial and transient re - stenosis due to hyperplastic reaction during the degradation of the prosthesis , with transient dysphagia in two patients resolved medically . - pubmed
Emotional modulation of the defense startle reflex ( RMS ) was assessed in 26 women at risk of suffering from bulimia nervosa ; they were assigned one of to two groups : high craving - trait and low craving - trait . - pubmed
Comparison of vildagliptin - metformin and glimepiride - metformin treatments in type 2 diabetic patients . - pubmed
METHODS : In a randomized , open - label , comparative study , 106 patients with type 2 diabetes were enrolled . - pubmed
The patient underwent laparoscopic left nephrectomy , and the tumor was histologically diagnosed as a sarcomatoid RCC . - pubmed
At the National Institute for Research in Tuberculosis , of 1048 LJ slopes with M. - pubmed
We report the case of an 81 - year - old man with oesophageal rupture secondary to volvulus of an intrathoracic stomach who underwent laparotomy with a repair of the oesophageal perforation and intrathoracic stomach , making a good recovery . - pubmed
METHODS : Between December 2002 and November 2010 , 25 patients with fecal incontinence were treated with gluteus maximus transplantation , which was caused by surgery of high anal atresia . - pubmed
CONCLUSION : Gluteus maximus transplantation can improve defecation controls in the patients with fecal incontinence after surgery of high anal atresia . - pubmed
Shigella are human - adapted Escherichia coli that have gained the ability to invade the human gut mucosa and cause dysentery(1,2 ) , spreading efficiently via low - dose fecal - oral transmission(3,4 ) . - pubmed
sonnei has been predominantly responsible for dysentery in developed countries but is now emerging as a problem in the developing world , seeming to replace the more diverse Shigella flexneri in areas undergoing economic development and improvements in water quality(4 - 6 ) . - pubmed
PATIENTS AND METHODS : Four eyes of 4 patients sustained an IOFB injury with deep impact . - pubmed
All patients have long - term follow - up ( mean , 22 months ) with no postoperative complications . - pubmed
Value of concomitant endoscopic balloon dilation for intestinal stricture during long - term infliximab therapy in patients with Crohn ' s disease . - pubmed
METHODS : The effectiveness of maintenance therapy with IFX was retrospectively evaluated in 185 patients with CD in a single center ( median observation period 24 months ) . - pubmed
The efficacy of concomitant EBD in patients with obstructive symptoms and high - level stricture was evaluated . - pubmed
Symptomatic high - level stricture occurred in 33 patients ( 17.8 % ) in the maintenance group and the cumulative surgery - free rate was significantly higher in the EBD combination compared with the non - EBD group ( P & lt ; 0.05 ) . - pubmed
While percutaneous instrumentation can be generally used in less displaced fractures , it remains controversial whether such techniques should also be performed in patients with severe fracture dislocation . - pubmed
This includes patients with severe traumatic kyphosis and/or dislocation in the coronar plane , particularly in concomitant neurological deficits that require additional decompression surgery . - pubmed
CASE PRESENTATION : The patient was a 76 - year - old woman who was diagnosed as having schizophrenia forty years ago . - pubmed
Functional characterization of T cell populations in a mouse model of chronic obstructive pulmonary disease . - pubmed
Epstein - Barr virus ( EBV ) , a common herpesvirus with high infection rate , is now suspected to be a risk or protective factor in food allergy . - pubmed
METHODS : 34 patients with an egg allergy and 34 healthy controls participated in this study . - pubmed
The serotypes and antibiotic resistance of strains of S.pneumoniae were determined using the capsular swelling method and the E - test . - pubmed
CONCLUSIONS : Serotype 19A strains were most frequently isolated from children with IPD treated in our hospital . - pubmed
We applied this methodology to rat C6 glioma cells and the Cyprinus carpio and searched the resulting peptide sequences against the protein database . - pubmed
Chromoendoscopy to detect early synchronous second primary esophageal carcinoma in patients with squamous cell carcinomas of the head and neck ? - pubmed
To evaluate the use of flexible esophagoscopy and chromoendoscopy with Lugol 's solution in the detection of early esophageal carcinomas ( second primary carcinomas ) in patients with squamous cell carcinoma of the head and neck ( HNSCC ) . - pubmed
All patients with newly diagnosed HNSCC underwent office - based Lugol 's chromoendoscopy . - pubmed
132 patients with HNSCC were enrolled in this study . - pubmed
Squamous cell carcinomas were detected in two patients , peptic esophagitis in 11 patients , gastric heterotopic mucosa in two patients , hyperplasia in two patients , and low- and high - grade dysplasia in three patients . - pubmed
Although only two patients with synchronous primary carcinomas were found among the patients , esophagoscopy should be recommended after detection of HNSCC to exclude secondary esophageal carcinoma or dysplasia . - pubmed
RESULTS : Twenty - three patients demonstrated clinical and radiographic evidence of atlantoaxial instability ( 13 men and 10 women , with a mean age of 42 years ) . - pubmed
After a period of follow - up , 9 of the 10 neurological deficit patients had completely recovered . - pubmed
The first patient was a 59 - year - old white woman treated for a secondary lung nodule of an advanced hepatocellular carcinoma . - pubmed
The second patient was a 61 - year - old white man followed - up for a non - small - cell lung cancer . - pubmed
Due to invasion and intrahepatic metastasis , the prognosis for patients with hepatocellular carcinoma ( HCC ) is poor . - pubmed
Anaemia to predict outcome in patients with acute coronary syndromes . - pubmed
BACKGROUND : Owing to the heterogeneous population of patients with acute coronary syndromes ( ACS ) , risk stratification with tools such as the GRACE risk score is recommended to guide therapeutic management and improve outcome . - pubmed
METHODS : A prospective registry of 1064 ACS patients ( 63 + - 14 years ; 73 % men ; 57 % ST - segment elevation myocardial infarction [ MI ] ) was studied . - pubmed
Subsequently , adding anaemia to the GRACE score led to reclassification of 595 patients into different risk categories ; 16.5 % patients at low risk ( & lt;= 5 % risk of death or rehospitalization for MI ) were upgraded to intermediate ( & gt;5 - 10 % ) or high risk ( & gt;10 % ) ; 79.5 % patients at intermediate risk were reclassified as low ( 55 % ) or high risk ( 24 % ) ; and 45.5 % patients at high risk were downgraded to intermediate risk . - pubmed
Rapid Re - challenge with Clozapine Following Pronounced Myocarditis in a Treatment - Resistance Schizophrenia Patient . - pubmed
Myocarditis is one of the life - threatening adverse effects which occurs in about 1 % of exposed patients . - pubmed
[ Effect of Ca ( OH ) 2 on the cytotoxicity of lipopolysaccharide extracted from Porphyromonas endodontalis in vitro ] . - pubmed
Peripheral T - cell lymphoma in a child with cutaneous involvement . - pubmed
PURPOSE : To determine the tear osmolarity in patients with tearing secondary to dry eye and other pathologies , and to determine the prevalence of dry eye disease among patients with tearing in an oculoplastics setting . - pubmed
Patients with dry eye had a significantly higher median tear osmolarity compared to that in patients with other diagnoses ( 308 mOsm / L vs. 294 mOsm / L , p & lt ; 0.0001 ) . - pubmed
CONCLUSIONS : A significant proportion of patients with tearing in an oculoplastics practice had dry eye disease . - pubmed
OBJECTIVES : The purpose of this article is to assess the distribution of undiagnosed HIV infection in men who have sex with men ( MSM ) in Southern and Eastern European countries , to describe the differences in epidemiology and behaviour between undiagnosed , diagnosed HIV - positive and HIV - negative MSM and to identify factors associated with undiagnosed HIV infection in the study population . - pubmed
RESULTS : HIV prevalence was 17 % in Barcelona , 12 % in Verona , 6 % in Bratislava , 5 % in Ljubljana , 5 % in Bucharest and 3 % in Prague while undiagnosed HIV infection was 47 , 62 , 67 , 83 , 85 and 57 % , respectively . - pubmed
Factors associated with undiagnosed HIV infection included attending sex - focused venues ( OR = 2.49 ) , reporting syphilis in the previous 12 months ( OR = 2.56 ) , using poppers at last sexual intercourse ( OR = 3.36 ) and having had an HIV test in the previous year ( OR = 2.00 ) . - pubmed
Low carbohydrates intake , soy protein , omega-3 ( w-3 ) fat , green teas , tomatoes and tomato products and zyflamend showed promise in reducing PCa risk or progression . - pubmed
The use of etanercept in rheumatoid arthritis patients with end - stage renal failure has not been well reported . - pubmed
We report here the case of 58 - years - old patient who was treated with 50 mg of etanercept once a week to control the activity of her disease . - pubmed
Our case showed the safety and efficacity of etanercept rheumatoid arthritis in patient with end - stage renal failure . - pubmed
To our knowledge , this is the first case report of sugammadex use in a patient with WPW . - pubmed
This report presents a case of general anesthesia management in a patient with WPW syndrome . - pubmed
CONCLUSION : We think that it is appropriate to use sugammadex to reverse rocuronium for the prevention of sudden hemodynamic changes in patients with WPW who underwent general anesthesia . - pubmed
Tips and tricks for DIEP flap breast reconstruction in patients with previous abdominal scar . - pubmed
All patients who underwent DIEP flap breast reconstruction between 2004 and 2014 were reviewed and divided into a control group ( CG ) and a scar group ( SG ) . - pubmed
With careful preoperative planning and appropriate technical strategies , successfully DIEP flap breast reconstruction can be performed without increased flap and donor - site complications in patients with preexisting abdominal scars . - pubmed
Role and Operative Technique of Portal Venous Tumor Thrombectomy in Patients with Pancreatic Neuroendocrine Tumors . - pubmed
INTRODUCTION : Venous tumor thrombi have been reported in as many as 33 % of patients with pancreatic neuroendocrine tumors ( pNETs ) . - pubmed
RESULTS : Among 245 patients with pNET that underwent pancreatectomy at our institution , 26 ( 11 % ) patients required surgical management of tumor involvement of the portal vein or its tributaries concomitant with pancreatectomy , including 9 ( 3.8 % ) patients who underwent portal venous tumor thrombectomy . - pubmed
Among patients with pNET who underwent thrombectomy at our institution , all nine had non - functioning tumors and eight ( 89 % ) had tumors of the body and/or tail of the pancreas . - pubmed
CONCLUSION : Venous tumor thrombectomy may be used to safely and effectively extract thrombi from the portal venous system in selected patients with advanced pNET concomitant with pancreatectomy . - pubmed
Two patients in the oPAE group with hypocontractile bladders experienced recurrence of symptoms and were treated with TURP . - pubmed
In the TURP group , urinary incontinence occurred in 4/15 patients ( 26.7 % ) , rupture of the prostatic capsule in 1/15 ( 6.7 % ) , retrograde ejaculation in all patients ( 100 % ) , and one patient was readmitted for temporary bladder irrigation due to hematuria . - pubmed
MATERIALS AND METHODS : From January 2002 to July 2010 there were 68 patients with advanced stage cervical carcinoma retrospectively analysed in Maternal and Child Health Hospital of Jiangxi Province . - pubmed
There were 36 patients ( 29 adenocarcinoma ( AC ) , six adenosquamous carcinoma ( ASC ) , and one undifferentiated carcinoma ) classified into observation group that was treated with radical radiation therapy + surgery ( total hysterectomy + bilateral salpingo - oophorectomy ) ; other 32 patients ( 26 AC , five ASC , and one undifferentiated carcinoma ) classified into control group that was treated with radical radiation therapy with no further surgery . - pubmed
BACKGROUND : People with eating disorders have difficulties in socio emotional functioning that could contribute to maintaining the functional consequences of the disorder . - pubmed
This article discusses variants of oral and oropharyngeal SCC and highlights those features that help distinguish human papillomavirus - related from human papillomavirus - unrelated SCC . - pubmed
It infects humans and livestock and causes Rift Valley fever . - pubmed
RVFV is considered an agricultural pathogen by the USDA , as it can cause up to 100 % abortion in cattle and extensive death of newborns . - pubmed
In some human cases of RVFV infection , the virus causes fever , ocular damage , liver damage , hemorrhagic fever , and death . - pubmed
We then characterized these cells as resistant to new RVFV infection , but sensitive to other viral infections , including Venezuelan Equine Encephalitis Virus ( VEEV ) . - pubmed
Clinicopathologic Factors Associated With Occult Lymph Node Metastasis in Patients With Clinically Diagnosed N0 Lung Adenocarcinoma . - pubmed
BACKGROUND : In some patients , clinical N0 ( cN0 ) lung adenocarcinoma diagnosed by preoperative computed tomography scanning and positron emission tomography scanning was staged as pathologic N1 ( pN1 ) or N2 ( pN2 ) postoperatively . - pubmed
METHODS : We conducted a retrospective chart review of 350 patients treated for cN0 lung adenocarcinoma by curative resection . - pubmed
RESULTS : Of 350 patients treated for cN0 tumors , 305 ( 87.1 % ) were confirmed postoperatively as having pN0 tumors , and 45 ( 12.9 % ) were confirmed as having pN1 or pN2 tumors . - pubmed
Finally , we show that the seizure - prone ryanodine receptor gain - of - function ( R2474S ) knockin mice have an unaltered repolarization phase but larger fAHP and increased AP frequency compared with their control littermates . - pubmed
A healthy microbiota effectively inhibits infection by restricting the ability of C. - pubmed
Additionally , there are only a few studies comparing isoflurane - induced cardiorespiratory effects between rat strains . - pubmed
Under anesthesia at more than 4 % , although prolongation of the RR and PR intervals was observed in all strains , shortening of the QTC interval was found only in SHR / Izm rats . - pubmed
Blood pressure and heart rate were remarkably reduced in SHR / Izm rats at higher concentrations , whereas the reduction was smallest in WKY / Izm rats among the three strains examined . - pubmed
These results suggested that SHR / Izm rats are more sensitive to suppressive effects of isoflurane anesthesia on cardiovascular function among these rat strains . - pubmed
METHODS : Retrospectively , we examined 210 tremor patients referred for electrophysiological recordings between January 2008 and January 2014 . - pubmed
The first step was to determine whether patients met neurophysiological criteria for their type of tremor . - pubmed
RESULTS : Most patients ( 87 % ) concurred with all core clinical neurophysiological criteria for their tremor type . - pubmed
METHODS : Nineteen patients with anterior circulation aneurysms ruptured during clipping , who admitted to the Department of Neurosurgery , Henan Provincial People 's Hospital from November 2012 to February 2014 , were enrolled . - pubmed
There was no residual aneurysm confirmed by postoperative CTA in 17 patients . - pubmed
The aneurysm was trapped and the patient paralysed on one side after operation . - pubmed
Role of n-3 Polyunsaturated Fatty Acids in Ameliorating the Obesity - Induced Metabolic Syndrome in Animal Models and Humans . - pubmed
The incidence of obesity and its comorbidities , such as insulin resistance and type II diabetes , are increasing dramatically , perhaps caused by the change in the fatty acid composition of common human diets . - pubmed
METHODS : CSP was identified and graded with 16 slice computed tomography ( CT ) machine in 138 patients of schizophrenia and 64 controls . - pubmed
RESULTS : We found 21.0 % of patients in schizophrenia group had abnormal CSP compared to only 9.4 % in control group ( P = 0.047 ) . - pubmed
These findings should promote awareness among physicians to make a timely diagnosis of HIV and to help physicians prioritize prevention and intervention strategies for anemia in HIV - infected patients . - pubmed
Seventy - eight patients subsequently developed MDS and nine patients developed CMML during 402 892 person - years . - pubmed
Given the robust results in preclinical models and mixed results in observational studies , controlled dietary interventions with standardized intakes are needed to better understand the interaction of specific fat and fiber subtypes on colon biology and ultimately CRC susceptibility in humans . - pubmed
Studies on the antidiabetic activities of Momordica charantia fruit juice in streptozotocin - induced diabetic rats . - pubmed
CONTEXT : Momordica charantia Linn ( Cucurbitaceae ) ( MC ) is used in folk medicine to treat various diseases including diabetes mellitus . - pubmed
OBJECTIVE : This study investigates the antidiabetic activities of Momordica charantia ( bitter gourd ) on streptozotocin - induced type 2 diabetes mellitus in rats . - pubmed
CONCLUSIONS : Momordica charantia presents excellent antidiabetic and antioxidant activities and thus has great potential as a new source for diabetes treatment whether it is used for prophylaxis or treatment . - pubmed
In ALS mouse models , edaravone suppresses motor functional decline and nitration of tyrosine residues in the cerebrospinal fluid . - pubmed
In all trials , the primary outcome measure was the changes in scores on the revised ALS functional rating scale ( ALSFRS - R ) to evaluate motor function of patients . - pubmed
Long - Term Outcomes of a Large Cohort of Patients with Eales ' Disease . - pubmed
This systematic review and NMA aimed to evaluate the safety and efficacy of different antifungal agents used for prophylaxis of IFI in patients with haematological disorders . - pubmed
Preimplantation genetic diagnosis is a subtype of IVF in which embryos are created for genetic diagnosis of hereditary disorders in order to avoid genetically affected children . - pubmed
Patients with traumatic cataract , corneal diseases , and preoperative astigmatism & gt;1.5 D were excluded from the study . - pubmed
CONCLUSION : SICS and phacoemulsification with this technique yield lesser astigmatism than clear corneal and scleral incisions , with the advantage of extension without suturing in complicated cases of phaco and in patients with rigid intraocular lens phacoemulsification gives better BCVA in a larger proportion of patients at 12 weeks . - pubmed
Circadian blood pressure patterns and blood pressure control in patients with chronic kidney disease . - pubmed
METHODS : In this observational study , we studied 547 patients referred to the hypertension clinic , of whom 224 ( 40.9 % ) had CKD . - pubmed
Patients with CKD presented as twice as higher prevalence of reverse dipper ( night - time peak ) for systolic BP and episodes of hypotension during daytime , independently of BP control . - pubmed
The case is presented on a 72 year - old woman with uncontrolled high blood pressure referred to the Urology Department due to the incidental finding of a right retroperitoneal mass . - pubmed
INTRODUCTION AND HYPOTHESIS : Our aim was to evaluate clinically relevant long - term outcomes of transvaginal mesh or native tissue repair in women with recurrent pelvic organ prolapse ( POP ) . - pubmed
METHODS : We performed a 7 - year follow - up of a randomized controlled trial on trocar - guided mesh placement or native tissue repair in women with recurrent POP . - pubmed
These include whole cell - based screenings , zebrafish larvae - based screenings and the impact of artificial granuloma research on the drug discovery process . - pubmed
Objectives : This study investigates the prediction of Non - small cell lung cancer ( NSCLC ) patient survival outcomes based on radiomic texture and shape features automatically extracted from tumor image data . - pubmed
Spearman 's rank correlation , Kaplan - Meier estimation and log - rank tests were used to identify features related to long / short NSCLC patient survival groups . - pubmed
Immune Consequences of in vitro Infection of Human Peripheral Blood Leukocytes with Vesicular Stomatitis Virus . - pubmed
BACKGROUND : Oncolytic vesicular stomatitis virus ( VSV ) can be delivered intravenously to target primary and metastatic lesions , but the interaction between human peripheral blood leukocytes ( PBLs ) and VSV remains poorly understood . - pubmed
Our study aimed to assess the overall immunological consequences of ex vivo infection of PBLs with VSV . - pubmed
Our results shed further light on immune mechanisms in response to VSV infection and the underlying VSV - PBL interactions bringing hope for improved cancer immunotherapies , particularly those based on intravenous delivery of oncolytic VSV . - pubmed
Radiotherapy ( RT ) is applied in prostate cancer patients with a biochemical recurrence ( BcR ) after radical prostatectomy ( RP ) . - pubmed
In all of the eight cases of vertical transmission , the diagnosis was after the birth of children infected with HBV , and in 3/8 ( 37.5 % ) , there was more than one case of infection by this mechanism per patient , totaling 13 children with the disease . - pubmed
majus excreted broad antifungal activity against Penicillium , Aspergillus and non - albicans Candida isolates comprising strains both sensitive and resistant to fluconazole . - pubmed
Additionally , it showed no cytotoxicity on human cells and the chemical characterization of the H. - pubmed
CONCLUSION : In patients with moderate to severe AVVR , restoration of atrioventricular valve competence prior to , or at the time of , Stage 2 surgery would likely lead to improved haemodynamics and clinical outcome as the models suggest that uncorrected AVVR can worsen across Stage 2 surgery . - pubmed
Furthermore , the antifungal activity of the as - prepared Ag NPs was tested against Cladosporium fulvum , which is the major cause of a serious plant disease , known as tomato leaf mold . - pubmed
Patients with metastatic RCC have an unusually poor prognosis and near - universal resistance to all current therapies . - pubmed
To improve RCC treatment and the survival rate of patients with RCC , there is an urgent need to reveal the mechanisms by which metabolic reprogramming regulates aberrant signaling and oncogenic progression . - pubmed
METHODS : Electronic and manual literature searches were conducted on PubMed / MEDLINE and the Cochrane Library on studies published until May 2018 to collect information about the effect of machined , moderately rough , and rough dental implant surfaces in patients with a history of periodontal disease . - pubmed
Accumulation and toxicity of thiamethoxam and its metabolite clothianidin to the gonads of Eremias argus . - pubmed
The significant declines in testosterone and prostaglandin D2 levels in the plasma indicated that thiamethoxam and clothianidin could cause androgen deficiency in male lizards . - pubmed
BACKGROUND : Exercise is prescribed for people with Parkinson ' s disease to address motor and non - motor impairments , including pain . - pubmed
, an immediate reduction in pain sensitivity following exercise ) is reported in the general population ; however , the immediate response of pain sensitivity to exercise in people with Parkinson ' s disease is unknown . - pubmed
The purpose of this study was to investigate if exercise - induced hypoalgesia is present following isometric and aerobic exercise in people with Parkinson ' s disease , and if so , if it varies with the dose of aerobic exercise . - pubmed
METHODS : Thirty people with idiopathic Parkinson ' s disease and pain - free age - matched controls completed two observational studies evaluating the response to : ( a ) right arm isometric exercise ; and ( b ) treadmill walking at low and moderate intensities . - pubmed
CONCLUSIONS : Overall , people with Parkinson ' s disease experienced an exercise - induced hypoalgesia response similar to that of the control group , the extent of which did not vary between mild and moderate doses of aerobic exercise . - pubmed
SIGNIFICANCE : Isometric and aerobic exercise reduces pain sensitivity in people with Parkinson ' s disease . - pubmed
The dog developed a self - resolving seroma . - pubmed
METHODS : A total of 969 pregnant women were randomly screened in first and second trimester , of which 8 developed Early - onset Preeclampsia , 29 Late - onset Preeclampsia , 35 Gestational Hypertension and 897 women had a normal outcome . - pubmed
Methods : Patients with controlled and uncontrolled acromegaly and as a control group ( CG ) patients without acromegaly between January 2010 and March 2014 were included . - pubmed
Results : Fifty - nine patients with acromegaly ( controlled n=30 , uncontrolled n=29 ) and 73 age and gender matched volunteers without acromegaly were evaluated . - pubmed
Six ( 20 % ) of controlled acromegaly patients , 10 ( 35 % ) of uncontrolled acromegaly patients and three ( 4 % ) of CG had inadequate bowel cleansing ( p<0.001 ) . - pubmed
A 60 - year - old female presented with cervical spinal cord compression caused by IgG4 - RD leading to several neurological deficits . - pubmed
Our aim was to investigate the possible role of inflammasome in the chronic subclinical inflammatory condition typical of RTT , by analyzing this complex in basal and lipopolysaccharide ( LPS )+ ATP - stimulated primary fibroblasts , as well as in serum from RTT patients and healthy volunteers . - pubmed
Is surveillance imaging in pediatric patients treated for localized rhabdomyosarcoma useful ? - pubmed
BACKGROUND : After the completion of therapy , patients with localized rhabdomyosarcoma ( RMS ) are subjected to intensive radiological tumor surveillance . - pubmed
This study retrospectively analyzed the value of off - therapy surveillance by comparing the survival of patients in whom relapse was detected by routine imaging ( the imaging group ) and patients in whom relapse was first suspected by symptoms ( the symptom group ) . - pubmed
METHODS : This study included patients with relapsed RMS after the completion of therapy for localized RMS who were treated in large pediatric oncology hospitals in France , the United Kingdom , Italy , and the Netherlands and who were enrolled in the International Society of Paediatric Oncology Malignant Mesenchymal Tumor 95 ( 1995 - 2004 ) study , the Italian Paediatric Soft Tissue Sarcoma Committee Rhabdomyosarcoma 96 ( 1996 - 2004 ) study , or the European Paediatric Soft Tissue Sarcoma Study Group Rhabdomyosarcoma 2005 ( 2005 - 2013 ) study . - pubmed
The survival times after relapse were compared with a log - rank test between patients in the imaging group and patients in the symptom group . - pubmed
RESULTS : In total , 199 patients with relapsed RMS were included : 78 patients ( 39.2 % ) in the imaging group and 121 patients ( 60.8 % ) in the symptom group . - pubmed
This study found no survival advantage for patients whose relapse was detected before the emergence of clinical symptoms . - pubmed
Regulatory effect of Garidisan on dysbiosis of the gut microbiota in the mouse model of ulcerative colitis induced by dextran sulfate sodium . - pubmed
Garidisan is composed of wild poppy and Artemisia frigida Willd and is commonly used for the treatment of UC in Inner Mongolia , China . - pubmed
Previous studies have shown that Garidisan has a good therapeutic effect on mice with UC , but the therapeutic mechanism is still unclear . - pubmed
In this study , we investigated the regulatory effect of Garidisan on dysbiosis of the gut microbiota in a UC mouse model and explored the possible mechanism of the therapeutic effect of Garidisan on UC . - pubmed
BACKGROUND : Enterovirus 71 ( EV71 ) is the main pathogen that causes severe hand , foot , and mouth disease with fatal neurological complications . - pubmed
This study reports the hen health and welfare portion based upon veterinary health inspections and compared mortality rates , skeletal abnormalities , causes of death determined by necropsy , and titers to infectious bronchitis and Newcastle disease viruses . - pubmed
We compared the outcomes among patients who were managed with pre - emptive pain management program with enhanced recovery after surgery ( Pre - emptive ) , enhanced recovery program after surgery alone ( ERAS ) and standard care ( control ) . - pubmed
Results : Of the 443 patients , 132 patients ( 30 % ) were in the pre - emptive pain management group , 90 ( 20 % ) patients were in the ERAS only group and 221 ( 50 % ) in the control group . - pubmed
Multivariate logistic regression analyses showed that the pre - emptive pain management program ( OR 0.06 ; 95 % CI , 0.03 , 0.11 , P<0.001 ) and robotic surgery ( OR 0.52 ; 95 % CI , 0.3 , 0.88 , P=0.02 ) were associated with lower odds of patients being discharged to home with opioid prescriptions . - pubmed
Association of left ventricular volume in predicting clinical outcomes in patients with aortic regurgitation . - pubmed
METHODS : We retrospectively analyzed 1100 consecutive patients with chronic moderate - severe and severe AR by echocardiography between 2004 and 2019 . - pubmed
To enhance understanding of the molecular nature of renal aging , we first compared whole - kidney RNA sequencing between naturally aging mice ( 24 - month - old ) and adenine - induced nephropathy in young mice ( 2 - month - old ) . - pubmed
Next , we compared the functional and structural renal consequences of aging and adenine - induced nephropathy between young ( 2 - month - old ) and old mice ( 18- to 22 - month - old ) . - pubmed
When mice were fed with adenine - enriched diet , aging kidneys showed more extensive tubular injury and fibrosis with stronger inflammatory response than young kidneys . - pubmed
Endocarditis due to Staphylococcus lugdunensis - a retrospective national registry - based study . - pubmed
We present characteristics of infective endocarditis ( IE ) caused by Staphylococcus lugdunensis and compare with IE caused by Staphylococcus aureus and other CoNS , in the National Swedish Registry of IE ( 2008 - 2018 ) . - pubmed
lugdunensis IE ( 20 % , n = 6 ) , than for IE caused by other CoNS ( 7 % ) or S. - pubmed
Preclinical opioid research using animal models not only provides mechanistic insights into the modulation of opioid analgesia and its associated side effects , but also validates drug candidates for improved treatment options for opioid use disorder . - pubmed
Data collected included patient characteristics , serum creatinine ( SCr ) level before and after TAE , iodine quantity of contrast media , time between computed tomography and TAE , diabetes mellitus , hemorrhage volume , and blood transfusion volume . - pubmed
Postpartum hemorrhage was finally controlled in all 47 patients , and they were subsequently discharged . - pubmed
In conclusion , emergency TAE for patients with uncontrollable postpartum hemorrhage was a safe and effective procedure , not only in terms of bleeding - related and other outcomes but also with respect to the risk of PC - AKI . - pubmed
Postoperatively , patients are at risk of severe hypocalcemia and hungry bone syndrome requiring close monitoring and replenishment . - pubmed
We investigated glycocalyx components in relation to preeclampsia in human samples . - pubmed
Histopathological and lipid changes in various organs of chicks ( Gallus domesticus ) caused by acute and chronic toxicity of metasytox - R and lebaycid . - pubmed
Different response to phalloidin in rats with various hepatomas . - pubmed
[ Special aspects of intensive care for comatose patients in surgical medicine ] . - pubmed
Capsaicin treatment of newborn rats results in the degeneration of primary sensory neurones involved in the mediation of chemogenic pain . - pubmed
Thirty fit patients ( 15 - 70 years , 46 - 98 kg ) undergoing body - surface operations were selected to include a wide range of adiposity ( 12 - 45 % of total body weight estimated from measurements of skinfold thickness ) . - pubmed
Thus ImAA joins histamine and the tetrapeptides ( ECF - A ) as anaphylaxis - associated selective chemoattractants for human eosinophils - pubmed
The echocardiographic findings in a 73 - year - old woman with constrictive calcified pericarditis are presented . - pubmed
In 373 hospitalized patients with bacteriologically positive bile samples , the aetiology was clarified by laboratory methods in 80 % of clinically verified gallbladder and biliary duct infections and in 15.5 % of diseases related to the biliary duct . - pubmed
Vincristine sulphate may benefit some patients and splenectomy is indicated in patients with severe uncontrollable haemorrhage . - pubmed
Right brain - damaged patients with left spatial neglect were examined on a tactile maze task . - pubmed
Pharmacological manipulations of anoxia - induced free fatty acid accumulation in the mouse brain . - pubmed
The accumulation of free fatty acid ( FFA ) in the brain occurs within minutes of anoxia , induced by exposing mice to a 100 % N2 atmosphere . - pubmed
[ Changes in the phase structure of the left ventricle systole in patients with obliterative atherosclerosis of the lower extremities after treatment with naphthalane baths ] . - pubmed
Fifty six patients with IHD and stenocardia , hypertensive disease were treated at the Naphthalan health resort . - pubmed
It was found that napthalane baths in the sitting position stimulate adaptation reserves of the body , improve the cardiac function , systemic and regional hemodynamics and may be used in the complex treatment of patients with obliterative atherosclerosis of the lower extremities including association of this disease with IHD and hypertension . - pubmed
Autonomic nervous system dysfunction and volume nonresponsive hypotension in hemodialysis patients . - pubmed
Studies were conducted in 9 dialysis patients with volume - nonresponsive hypotension , 6 dialysis patients with volume - responsive hypotension and in 10 normal subjects in an effort to evaluate the role of dysfunction of the autonomic nervous system ( ANS ) in the genesis of volume - nonresponsive hypotension . - pubmed
Patients with volume - nonresponsive hypotension displayed significant derangements in the function of ANS as compared to normal subjects and to patients with volume - responsive hypotension . - pubmed
Data show that dysfunction of ANS plays an important role in the genesis of volume - nonresponsive hypotension in dialysis patients . - pubmed
We now report the detection of potentially activating mutations of the human FMS gene in vivo . - pubmed
As many as 139 patients with dilated cardiomyopathy were examined for the effect of the clinical , ECG , x - ray , phono- , echo- and angiocardiographic indicators and heart catheterization data on the disease outcomes for 3 years after the examination . - pubmed
Subclinical hepatotoxicity developed in 5 patients . - pubmed
Patients who had hepatic and / or pulmonary abnormalities develop received higher doses of amiodarone ( 440 + /- 27 vs 340 + /- 18 mg / day ) , but also had a higher amiodarone : DEA ratio suggesting that dose - dependent kinetics contributed to the higher concentrations . - pubmed
The haemodynamic dose - response effects of intravenous amrinone were measured in 16 male patients , aged 40 - 65 years , with radiographic and haemodynamic evidence of left ventricular failure 4 - 18 h after acute myocardial infarction . - pubmed
Experimental combined hormone therapy on human breast carcinomas serially transplanted into nude mice . - pubmed
Experimental combined hormone therapy with tamoxifen , aminoglutethimide and medroxyprogesterone acetate was investigated using three hormone - dependent human breast carcinomas serially transplanted into nude mice . - pubmed
It was shown that in nephropathy , the orderliness parameter increases and the hydrophoby of probe I localized in a red cell suspension of nephropathy patients diminishes as compared with analogous parameters in healthy pregnant women . - pubmed
In a prospective investigation the clinical relevance of endoscopically confirmed lesions of the glenoid labrum in 46 patients is examined . - pubmed
A case of giant cell myocarditis in a patient with non - Hodgkin ' s lymphoma is reported . - pubmed
In vitro erythrocyte agglutination developed in 3 hospitalized horses receiving heparin treatment . - pubmed
Similar abnormalities in erythrocyte counts and MCV have been reported in healthy horses treated with heparin and have been cited as evidence of hemolysis and regenerative anemia . - pubmed
Since urine culture and urinalysis are both of uncertain reliability in diagnosing symptomatic urinary tract infections in patients with chronic urinary catheters , we performed sequential quantitative cultures and urinalyses on 177 urine specimens from 14 patients with long - term urinary catheters during a 12 - month period . - pubmed
Gastritis , duodenogastric reflux and bacteriology of the gastric remnant in patients operated for peptic ulcer by Billroth I operation . - pubmed
Duodenogastric reflux was significantly greater in the gastrectomized patients than in the controls . - pubmed
Of the operated patients , 6 % had normal stump mucosa and 80 % had atrophy . - pubmed
[ Mesotheliomas in golden hamster . - pubmed
[ Summary of recent virological studies in human hemopathies ] . - pubmed
[ The hypokalemia and kaliuresis after intravenous administration of a sympathomimetic in man ] . - pubmed
[ Eosinophilia in the rat uterus following estrogen treatment ] . - pubmed
[ The effect of the serum of patients with various forms of diabetes mellitus on the lipolytic activity and glucose uptake of the adipose tissue ] . - pubmed
The neuroendocrine system of normal human appendix , ileum and colon , and in neurogenic appendicopathy . - pubmed
[ Detection and characterization of the plasmids of the plague microbe which determine the synthesis of pesticin I , fraction I antigen and " mouse " toxin exotoxin ] . - pubmed
Phagocytosis and transport of carbon particles in the glomerular lesions caused by Habu snake venom ] . - pubmed
[ Early and late results of aorto - coronary bypass surgery in the children with Kawasaki disease ( author 's transl ) ] . - pubmed
Short - term parenteral and peroral testosterone administration in men with alcoholic cirrhosis . - pubmed
Serum concentrations of testosterone were measured in 24 male patients with alcoholic cirrhosis during testosterone administration . - pubmed
This ligament is the most frequently disrupted ligament in the human knee , yet wide disagreement exists concerning the effects of its rupture and the appropriate means of treatment . - pubmed
In 15 patients with chronic active hepatitis the median hepatic copper content was 39 micrograms / g dry weight at the start and 28 micrograms / g dry weight at the end of the observation period , during which the clinical condition was improved in most patients . - pubmed
The hepatic copper content did not change significantly ( 41 versus 54 micrograms / g dry weight ) in 28 patients with hepatobiliary disorders associated with inflammatory bowel disease . - pubmed
In 27 patients with primary biliary cirrhosis the median hepatic copper concentration was initially 176 micrograms / g dry weight , and at the follow up 186 micrograms / g dry weight . - pubmed
[ Chronic experimental allergic neuritis as an experimental model of human idiopathic chronic polyradiculoneuropathy ] . - pubmed
Evaluation of ototoxicity of amino - glycoside antibiotics in rabbits . - pubmed
The ototoxicity was GM greater than DKB greater than KM greater than AMK with the dose of 100 mg / kg , which coincide with many of the conventional reports on animal experiments . - pubmed
Usually , the doses of drugs used in the ototoxicity studies with animals are more than 10 times higher than those used clinically . - pubmed
Consequently , problems still exist in infering the ototoxicity of drugs in humans directly from the results obtained from animal experiments . - pubmed
Even so , high values give an effective expression of its progress by identifying patients with a greated likelihood of recurrence . - pubmed
Effect of androgen depletion on postoperative regrowth of androgen - dependent and -independent Shionogi carcinomas in mice . - pubmed
After 20 or 15 days , most of the developed tumors were excised and the mice were divided into 3 groups . - pubmed
The cumulative 120 - day mortality after transplantation of SC115 tumor into mice was significantly lower in the immediate androgen removal group ( 10 % , 6/59 ) than in the androgen - injected group ( 59 % , 51/87 ) or the delayed androgen removal group ( 42 % , 19/45 ) . - pubmed
The cumulative mortalities in mice with androgen - independent NHD and NHF tumors in the immediate androgen removal groups ( 97 and 91 % , respectively ) were similar to those in the androgen - injected groups ( 90 and 95 % , respectively ) . - pubmed
All non - operated and TP - injected mice grafted with SC115 and androgen - independent tumor died due to the tumors within 50 and within 30 days after the transplantation , respectively . - pubmed
METHODS : A 17 - year - old female presented with a left intraventricular and intraparenchymal cerebral hemorrhage resulting from a 1 cm left posterior choroidal AVM . - pubmed
CONCLUSION : We recommend that patients with angiographic obliteration of AVMs receive further treatment , preferably resection , or be followed with serial angiography . - pubmed
Evidence of antitumor effect was noted particularly among untreated patients with gastrointestinal primaries . - pubmed
Is man helpless against cancer ? - pubmed
The effect of zinc deficiency on wool growth and skin and wool follicle histology of male Merino lambs . - pubmed
The aims of this work were to quantify the requirements of Zn for wool growth in growing male Merino lambs , and to describe the histological lesions of Zn deficiency in skin and wool follicles . - pubmed
Sheep fed on the diet containing 4 mg Zn / kg showed clinical signs of Zn deficiency and lower feed intakes and wool growth than sheep in the other groups . - pubmed
Sheep from other groups showed no clinical signs of Zn deficiency , and mean feed intakes and growth rates did not differ significantly between sheep fed on diets containing 10 , 17 or 27 mg Zn / kg . - pubmed
Electromyographic studies of 15 obturator internus muscles in 10 healthy adult male volunteers and 3 other muscles in patients with documented spastic anal sphincters demonstrated the ability of the obturator internus muscles to contract during straining at stools . - pubmed
The proposed surgical approach was studied in 9 cadavers ( 5 stillbirths and 4 adults ) , followed by formal anatomical dissection of the obturator internus muscle and tendon , pudendal nerve and vessels , inferior rectal nerve and nerve to the obturator internus . - pubmed
We evaluated the effectiveness and safety of zinc in 5 patients with Wilson ' s disease aged from 19 to 40 years . - pubmed
From the present study it can be concluded that nodular hyperplasia represents monoclonal parathyroid neoplasia , which might explain why patients with nodular hyperplasia in renal hyperparathyroidism are refractory to medical treatment , requiring parathyroidectomy . - pubmed
A cough - induced increased in intra - abdominal pressure was recorded vaginally in 26 women with stress incontinence and urinary leakage was detected electronically . - pubmed
Campylobacter jejuni isolates from two epidemic outbreaks in Sweden , one milkborne ( 35 isolates ) and one waterborne ( 17 isolates ) , and one waterborne outbreak in Norway ( 11 isolates ) , as well as 30 solitary isolates from Swedish patients with gastroenteritis , were analyzed . - pubmed
PURPOSE : To evaluate the combination of vinorelbine , ifosfamide and cisplatin ( VIP ) in patients with advanced non - small - cell lung cancer ( NSCLC ) . - pubmed
We report on 2 cases of cardiac hemangioma , diagnosed occasionally in the first patient or due to gastroenteric symptoms in the second patient . - pubmed
Both patients underwent tumor resection in hypothermic cardiopulmonary bypass . - pubmed
Effect of combination therapy of troglitazone and sulphonylureas in patients with Type 2 diabetes who were poorly controlled by sulphonylurea therapy alone . - pubmed
Two hundred and ninety - one patients with Type 2 diabetes ( age 21 - 81 years ) whose previous glycaemic control by sulphonylureas was judged stable but unsatisfactory ( fasting plasma glucose ( FPG ) & gt ; 8.3 mmol I-1 ) were randomly allocated into the troglitazone treatment group ( troglitazone group , n = 145 ) or the placebo treatment group ( placebo group , n = 146 ) . - pubmed
The cumulative patient survival estimated by the Kaplan - Meier method showed a worse prognosis for patients belonging to group 1 , where higher AgNOR values , not only in primary carcinomas but also in lymph node and distant metastases , were found . - pubmed
Changes of ultrasonography and two serum biochemical indices for hepatic fibrosis in schistosomiasis japonica patients one year after praziquantel treatment . - pubmed
OBJECTIVE : To observe the changes of abdominal sonography and 2 biochemical indicators for hepatic fibrosis before and after treatment with praziquantel in schistosomiasis japonica patients . - pubmed
CONCLUSIONS : Parameters of hepatic fibrosis either by ultrasonography or by the 2 biochemical tests showed a significant improvement in 55 patients 1 year after treatment , although some of the indices did not yet return to normal levels . - pubmed
Analysis of the clinical case material , covering 382 patients with diagnosis diabetic gangrene , is done with the purpose to reduce the percentage of disabling high - level amputations , and determine with precision the scope of operative activity , indications for operative intervention and type of surgical procedure in diabetic patients . - pubmed
These results are consistent with a specific acute inflammatory component to TBI in children . - pubmed
STUDY DESIGN : This prospective study used 87 subjects diagnosed by their physicians with unilateral benign paroxysmal positional vertigo of the posterior semicircular canal . - pubmed
[ Seroepidemiological survey of TT virus ( TTV ) infection in an endemic area for hepatitis C virus ] . - pubmed
Seroepidemiological survey of TT virus ( TTV ) infection was performed in the inhabitants living in an endemic area for hepatitis C virus ( HCV ) in Gifu prefecture , Japan . - pubmed
The TTV DNA - positive rate of the inhabitants with HCV infection was 21.4 % higher than that of the inhabitants without HCV infection 10.0 % . - pubmed
In the present survey , the rate of liver dysfunction of TTV DNA - negative inhabitants was not different from that of TTV DNA - positive inhabitants . - pubmed
Chronic alcohol treatment impairs host response to bovine mycobacterium infection from BCG . - pubmed
Central nervous system ( CNS ) pathology was the main cause of death in 17 % of the patients ( n = 31 ) , with a predominance of IHP in this particular group . - pubmed
001 ) and toxoplasmosis ( 9.67 vs 4.44 % ) ( P & lt ; 0.001 ) were significantly more frequent in the group of patients who died due to CNS causes than in the control group . - pubmed
METHOD : A single - center , blinded study in otherwise healthy humans ( n= 52 ) with localized mild to moderate AP was carried out , using the following groups : group A ( n= 12 ) , no oral hygiene for 14 days ; group B ( n=20 ) , routine oral hygiene ( ROH ) for 14 days ; group C ( n=20 ) , supra - gingival oral irrigation plus ROH for 14 days . - pubmed
Severe fungal infections were noted in 2 patients treated with MMF . - pubmed
Malignancy occurred in 1 patient ( pancreas graft lymphoma ) in MMF . - pubmed
Cyclophosphamide in the treatment of idiopathic pulmonary fibrosis : a prospective study in patients who failed to respond to corticosteroids . - pubmed
STUDY OBJECTIVES : To prospectively examine the role of cyclophosphamide in patients with idiopathic pulmonary fibrosis that is unresponsive to or intolerant of high - dose steroid treatment . - pubmed
PATIENTS : Nineteen patients with biopsy specimen - proven usual interstitial pneumonia who failed to respond ( n = 16 ) or experienced adverse effects ( n = 3 ) from corticosteroid treatment ( 1 mg / kg / d for 3 months ) . - pubmed
Toxicity associated with cyclophosphamide was substantial ; more than two thirds of the patients developed drug - related adverse effects , and almost half discontinued the drug prematurely due to side effects . - pubmed
CONCLUSIONS : Cyclophosphamide therapy is of limited efficacy in patients with idiopathic pulmonary fibrosis who fail to respond or who experience adverse effects from corticosteroid treatment , and adverse effects often complicate its use . - pubmed
Characterisation of the biochemical and biological variations from the venom of the death adder species ( Acanthophis antarcticus , A. - pubmed
We report on species variation in the venoms of the three species of death adder ; the Common death adder ( Acanthophis antarcticus ) , the Northern death adder ( Acanthophis praelongus ) and the Desert death adder ( Acanthophis pyrrhus ) . - pubmed
Actinobacillus suis infection in pigs in Australia . - pubmed
Comparative analysis of the whole set of rRNA operons between an enterohemorrhagic Escherichia coli O157 : H7 Sakai strain and an Escherichia coli K-12 strain MG1655 . - pubmed
We have managed 25 patients with TCA , of whom 5 had total intestinal involvement and died . - pubmed
It is unethical and incompetent to deny the scale and nature of human reactions to trauma . - pubmed
During the course of a large - scale clinical trial , a subset of patients reported the onset of symptoms and signs of cardiac failure that appeared to be aggravated by concomitant exposure to anthracyclines . - pubmed
However , new insights into the pathways that lead to other forms of heart failure have identified a pivotal role for myocyte survival pathways in preventing the onset of cardiomyopathy and associated heart failure in genetically engineered animal models of the disease . - pubmed
The possibility exists that the divergent susceptibility for the onset of cardiotoxicity among patients who have received trastuzumab might ultimately reflect an inherent genetic susceptibility to the diverse mechanisms that initiate , promote , and suppress the complex pathways to heart failure . - pubmed
METHODS AND RESULTS : Sixteen pigs with left ventricular hypertrophy ( LVH ) secondary to ascending aortic banding and 10 normal pigs ( N ) were studied . - pubmed
Nine of the 16 animals with LVH developed congestive heart failure ( CHF ) , as evidenced by ascites ( 100 to 2000 mL ) . - pubmed
BACKGROUND : PCR protocol for Vibrio cholerae , the causative agent of the diarrheal disease cholera has been described in this report . - pubmed
Recombinant antigens to establish a model of autoimmunity in mice . - pubmed
We applied this technique in a woman who had received sterilising chemotherapy for lymphoma . - pubmed
METHODS : A 36 - year - old woman underwent a right oophorectomy with cryopreservation of ovarian cortical strips before receiving high - dose CBV chemotherapy for a third recurrence of Hodgkin ' s lymphoma . - pubmed
FINDINGS : 7 months after reimplantation of ovarian cortical strips , the patient reported resolution of hot flashes and , for the first time , oestradiol was detected in the serum . - pubmed
The patient had one menstrual period , but by 9 months after the implantation , her sex steroid concentrations had returned to those seen with ovarian failure . - pubmed
INTERPRETATION : Orthotopic reimplantation of frozen / thawed ovarian cortical strips is a well tolerated technique for restoring ovarian function in women treated with sterilising chemotherapy for cancer . - pubmed
Venous thrombosis in patients with solid tumors : determination of frequency and characteristics . - pubmed
Irinotecan appears active and relatively well tolerated in patients with relapsed aggressive or indolent NHL . - pubmed
We reviewed our experience over a 5 - year period and identified eight adult patients with incapacitating respiratory symptoms compatible with HPS . - pubmed
Underlying liver disease was caused by hepatitis C ( 2 patients ) , primary biliary cirrhosis ( 1 patient ) , cryptogenic cirrhosis ( 1 patient ) , alcohol ( 2 patients ) , and hepatitis C with alcohol ( 2 patients ) . - pubmed
Severe hypoxemia was present in seven patients ( Pa(O2 ) 51.5 + /- 8.2 mm Hg ) . - pubmed
Three patients had complicating pulmonary hypertension . - pubmed
Resolution of oxygen dependency occurred in all patients but was delayed in the two patients exhibiting complicating pulmonary hypertension ( 288.5 + /- 37.4 v 53.5 + /- 35.7 days ) . - pubmed
This supports the newly implemented United Network for Organ Sharing ( UNOS ) criteria , that LT for HPS may be extended to include patients with Pa(O2 ) & lt ; 60 mm Hg . - pubmed
We combined PET and magnetic resonance ( MR ) imaging in the planning of SBB in 9 children ( 5 males and 4 females , aged 2 - 14 years ) with infiltrative , ill - defined brain lesions . - pubmed
This preliminary series suggests that combining PET and MR imaging in the planning of SBB in children ( 1 ) improves the diagnostic yield of SBB in infiltrative , ill - defined brain lesions , ( 2 ) makes it possible to reduce the sampling in high - risk / functional areas and ( 3 ) improves the quality of therapeutic management of pediatric brain tumors . - pubmed
Repeated peripheral airway hyperpnea causes inflammation and remodeling in dogs . - pubmed
We used a canine model of hyperpnea with cold , dry air to test the hypothesis that repeated cooling and desiccation of peripheral airways can cause asthma - like pathology . - pubmed
Term placentae were collected from non - diabetic subjects and five groups of diabetic women classified according to duration , severity and insulin dependence . - pubmed
Influence of 6 - week exercise training on erythrocyte and liver antioxidant defense in hyperinsulinemic rats . - pubmed
High dosage of fructose in rats causes insulin resistance and hyperinsulinemia . - pubmed
This study investigates the effect of physical exercise on oxidant - antioxidant balance in rats fed a high fructose diet , which show characteristic features of insulin resistance . - pubmed
Physical training to these rats reversed the adverse effects , which could be important in alleviating the pathological consequences of insulin resistance . - pubmed
In spite of significant advances in management , mortality in patients suffering from heart failure remains unacceptably high and new therapies are urgently needed . - pubmed
Recently , several large clinical trials have shown a significant reduction in both morbidity and mortality in heart failure patients when beta - blockers are added to standard therapy . - pubmed
Needle biopsy of pleura ; an evaluation in patients with pleural effusion of neoplastic origin . - pubmed
Effect of whole - body x - irradiation on the insulin resistance of fasted rats . - pubmed
EFFECTIVENESS OF CAPREOMYCIN AGAINST EXPERIMENTAL TUBERCULOSIS OF MICE AND GUINEA PIGS . - pubmed
Effects of an acute salt load in a case of primary hyperaldo - steronism before and nine months after surgical cure : comparison with normal subjects and patients with essential hypertension before and after reduction of their elevated pressure with drug treatment . - pubmed
Viral hepatitis ( VH ) is almost as old as human beings , at least as old as known human history . - pubmed
The mortality figures are projected to show a 2- to 3 - fold increase over the next two decades as hepatitis C virus - infected patients develop cirrhosis , which makes this the leading indication for liver transplantation . - pubmed
The list of hepatotropic viruses is well known , including hepatitis A ( HAV ) , B ( HBV ) , C ( HCV ) , D ( HDV ) , E ( HEV ) , G ( HGV ) and F ( HFV ) . - pubmed
HGV and HFV are excluded from the present review , mainly because they are questionable in relation to the causation of liver disease . - pubmed
Our knowledge of HAV , HBV , HDV and HEV has accumulated over the last decade , so the present discussion is focused on HCV , which is currently generating considerable concern and controversy , and is the leading cause of chronic liver disease worldwide . - pubmed
Pathologic features of Crohn ' s disease were present in 4 patients preoperatively and 15 more after repeat ileal pouch - anal anastomosis . - pubmed
Four patients had clinical features of Crohn ' s disease . - pubmed
Although pouch failure occurs more frequently than after primary ileal pouch - anal anastomosis , patient satisfaction and quality of life are high . - pubmed
METHODS : A total of 221 patients were studied after resection for gastric cancer , 110 after D1 surgery and 111 after D3 surgery . - pubmed
Development of atrial fibrillation in patients with atrioventricular block after atrioventricular synchronized pacing . - pubmed
Many studies have evidenced an increased incidence of AF in patients receiving single chamber ventricular pacing ( VVI ) when compared with those undergoing an atrial - based system ( AAI or DDD ) . - pubmed
However , the difference in incidence of AF between two atrial - based systems ( VDD , DDD ) in patients with AV block was still controversial . - pubmed
This study was conducted to compare the development of AF between different modes of pacemakers ( VDD and DDD ) in patients with symptomatic AV block . - pubmed
A retrospective review was conducted of the detailed records of all consecutive patients who received permanent pacemakers due to symptomatic bradycardia from March 1995 to March 2000 . - pubmed
The patients were divided into two groups : VDD ( n = 100 ) and DDD ( n = 52 ) . - pubmed
The authors suggest that VDD pacing may be a better choice than the DDD system for patients with AV block , but without clinical evidence of sinus node dysfunction , and if an atrial lead is required , it should be placed close to the Bachmann 's bundle . - pubmed
OBJECTIVE : In spinal cord injured ( SCI ) subjects , exaggerated withdrawal reflexes associated with a dominant flexor pattern irrespective of stimulation site have been reported . - pubmed
The reflexes in biceps femoris and vastus lateralis muscles were small and associated with weak knee flexion at all 10 sites in the SCI subjects and in the controls . - pubmed
The expansion is most likely due to lack of descending inhibitory control and/or increased sensitivity of the spinal reflex loop in the SCI subjects . - pubmed
Noninvasive assessment of tumor vascularity by contrast - enhanced ultrasonography and the prognosis of patients with nonresectable pancreatic carcinoma . - pubmed
BACKGROUND : Studies have shown that angiogenesis is one of the factors that influences the prognosis of patients with solid tumors , including pancreatic carcinomas . - pubmed
However , none have assessed noninvasively the relation between angiogenesis and prognosis in patients with pancreatic carcinoma . - pubmed
The objectives of this study were to assess the vascularity of pancreatic carcinoma noninvasively by contrast - enhanced US and to clarify the prognostic value of tumor vascularity in patients with nonresectable pancreatic carcinoma . - pubmed
METHODS : Thirty - five consecutive patients with pathologically confirmed , nonresectable pancreatic carcinoma were examined with contrast - enhanced US before systemic chemotherapy . - pubmed
The median survival also was longer in patients who had avascular tumors ( 267 days vs. 115 days , respectively ; P=0.0034 ; log - rank test ) . - pubmed
CONCLUSIONS : The current results indicated that contrast - enhanced US may be useful in assessing the prognosis of patients with nonresectable pancreatic carcinoma who receive systemic chemotherapy . - pubmed
A 35 - year - old Chinese man presented with acute thyrotoxic periodic paralysis complicated by near - fatal cardiac arrhythmias due to persistent hypokalaemia , despite maximum potassium supplementation . - pubmed
In this unusual case of severe refractory hypokalaemia leading to ventricular fibrillation in a patient with underlying thyrotoxicosis , the potential dangers concerning the use of dextrose infusion and beta - adrenergic agent for resuscitation are highlighted . - pubmed
Fifty - one patients with 73 idiopathic clubfeet were recruited . - pubmed
The study group consisted of 38 ( 51.3 % ) patients with acute myocardial infarction ( AMI ) and 36 ( 48.6 % ) with unstable angina pectoris . - pubmed
OBJECTIVE : To assess the impact of carotid endarterectomy on blood pressure homeostasis and baroreflex function , with particular reference to the presence or absence of significant contralateral carotid artery disease , we conducted a prospective study in 80 patients with symptomatic extracranial carotid disease undergoing carotid endarterectomy in a regional teaching hospital over 2 years . - pubmed
METHODS : Patients were divided into two groups : the control group ( n = 37 ) had no significant contralateral carotid disease ; patients in the diseased group ( n = 23 ) had either & gt;70 % stenosis or occlusion of the contralateral carotid artery . - pubmed
Seventeen patients with abnormal heart rhythms , poor quality recordings , or with intermediate degrees of contralateral carotid stenosis were excluded . - pubmed
There were significant reductions in baroreflex sensitivity and a hypertensive shift in the operating set point , the magnitude of which was significantly greater in patients with contralateral carotid disease . - pubmed
Patients with contralateral carotid stenosis have a reduced baroreflex reserve and show greater baroreflex dysfunction and hemodynamic instability after endarterectomy . - pubmed
The persistence of isolated tumor cells in bone marrow from patients with breast carcinoma predicts an increased risk for recurrence . - pubmed
Gnotobiotic dogs have been used to study the pathogenesis of acquired immunodeficiencies associated with canine distemper virus ( CDV ) . - pubmed
In recent years , the laboratory at OSU , in conjunction with University of Pennsylvania personnel have begun a series of long - term studies of dogs affected with the canine X chromosome - linked severe combined immunodeficiency ( XSCID ) syndrome . - pubmed
XSCIDs dogs , raised within a gnotobiotic environment for up to 3 years remain clinically healthy and are , in every respect normal except for the persistent T - cell defect and the failure to develop lymph nodes . - pubmed
The number of olfactory mucosal neoplasms was reduced by 25 % after 1 year of alachlor treatment in rats that received both alachlor and Ro 28 - 2653 . - pubmed
Catha edulis also leads to several peripheral effects that include increases in blood pressure and has been associated with the increased incidence of acute coronary vasospasm and myocardial infarction . - pubmed
Catha edulis also accounts for a number of gastrointestinal tract problems , oesophagitis , gastritis and delay intestinal absorption , as well as the development of oral keratotic white lesions at the site of chewing . - pubmed
Administration of Catha edulis extracts showed a deranged systemic capacity to handle oxidative radicals and induces cytotoxic effects in cells of liver and kidney , as well as induction of cell death in various human leukaemia cell lines and in peripheral human blood leukocytes . - pubmed
No death or toxic effects were observed among animals . - pubmed
Does abdominal aorta clamping , as a method of spinal ischemia in rats , really work ? - pubmed
Our aim was to highlight both morphological and functional abnormalities in a same group of 10 SD patients , in the entire brain , using a " state of the art " methodology ( optimized VBM procedure , PET data corrected for partial volume effects and voxel - based analyses ) . - pubmed
We showed that main alterations concerned the left temporal lobe , in accordance with the striking impairment of semantic memory in SD patients , as well as the hippocampal region , which may partly explain their moderate episodic memory deficits . - pubmed
Amelioration of benzo ( a ) pyrene - induced lung carcinogenesis in strain A mice by diphenylmethyl selenocyanate . - pubmed
BP was given at a dose of 0.2mg / mouse to initiate lung carcinogenesis in strain A mouse and the Se compound was given orally at a dose of 3mg / kgb.w . - pubmed
SSc patients were grouped into 22 patients with limited cutaneous SSc ( lcSSc ) and 27 patients with diffuse cutaneous SSc ( dcSSc ) . - pubmed
Individuals with functional hypothalamic hypogonadism typically engage in a combination of behaviors that concomitantly heighten psychogenic stress and increase energy demand . - pubmed
The increasing number of cancers seen early after transplantation and the increased risk of developing a cancer due to the older age of recipients draw attention to the importance of regular oncologic screening in patients on the waiting list and after transplantation . - pubmed
METHODS : Eightyone patients who underwent resective extratemporal epilepsy surgery were retrospectively studied concerning ( a ) age at surgery , ( b ) onset of epilepsy , ( c ) duration of epilepsy , ( d ) number of seizures at the time of presurgical evaluation , ( d ) number of presurgically tested antiepileptic substances and ( f ) number of seizure types . - pubmed
RESULTS : 33 patients ( 40.7 % ) were seizure free two years after surgery . - pubmed
The recurrence rate in patients with one or more seizures per day was more than two - fold if compared with patients with fewer seizures . - pubmed
The remaining demographic factors did not show a significant association with seizure outcome in our 81 patients . - pubmed
OBJECTIVE : To explore the coagulation indexes and offer a valuable reference for clinic therapy and prognosis in patients with oral squamous cell carcinomas ( OSCCs ) . - pubmed
All patients with OSCCs were divided into three groups included primary tumor , neck metastasis of lymph nodes and recurrence . - pubmed
RESULTS : The index of PT in patients with OSCCs was longer than that of healthy people . - pubmed
CONCLUSION : PT and APTT may be the useful indexes for clinic therapy and prognosis in patients with oral squamous cell carcinomas . - pubmed
A 51 - year - old man complained of left facial swelling and recurrent nasal bleeding . - pubmed
Combination chemotherapy with vincristine , doxorubicin , cyclophosphamide / ifosfamide with mesna and etoposide was administered ; however , the tumor was unresponsive and the patient died after around 3 months . - pubmed
Despite years of intense study by many investigators , it may appear that we have made little progress towards a molecular understanding of mammalian sperm binding to the egg zona pellucida . - pubmed
Nevertheless , a retrospective view of the literature suggests that some common principles are emerging regarding the molecular basis of mammalian sperm - zona binding , both with respect to the nature of the components that mediate binding , as well as the involvement of distinct receptor - ligand interactions , that involve both protein- and carbohydrate - dependent mechanisms of binding . - pubmed
Traditionally Boswellia serrata extract is used in the Indian Ayurvedic medicine for the treatment of inflammatory diseases . - pubmed
In 2002 the EMEA designated Boswellia an orphan drug status for the treatment of peritumoral oedema . - pubmed
All consecutive patients younger than 14 years with a first remote symptomatic unprovoked seizure who were seen at our hospital between 1994 and 2006 were included in the study and prospectively followed . - pubmed
A total of 55 children out of 63 were affected by a static encephalopathy of pre- or perinatal origin . - pubmed
Genomics of human glioblastoma multiforme : a glimpse of the future . - pubmed
There is a spectrum of acute illness for individuals who ingest toxigenic Escherichia coli , ranging from no symptoms to self - limited gastroenteritis , to full acute hemolytic uremic syndrome . - pubmed
PURPOSE : Bisphosphonate - associated osteonecrosis of the jaw ( BONJ ) is defined as the presence of exposed bone for at least 8 weeks in patients with exposure to bisphosphonates and no history of radiotherapy to the jaw . - pubmed
We report 5 patients with a history of bisphosphonate use , sinus tracts or deep periodontal pockets and radiographic findings typical for BONJ but with no evidence of exposed necrotic bone at the first evaluation visit . - pubmed
Patients had multiple myeloma ( 2 ) , multiple myeloma and prostate cancer ( 1 ) , monoclonal gammopathy of unknown significance ( 1 ) and osteoporosis ( 1 ) . - pubmed
Subsequently , 4 patients developed exposed bone and 1 patient had necrotic bone removed from the jaws . - pubmed
CONCLUSION : We report 5 patients with a history of bisphosphonate therapy where 4 patients had persistent sinus tracts and a fifth , severe bone loss . - pubmed
Four patients had radiographic findings typical for BONJ , and all subsequently developed necrotic bone . - pubmed
We propose modifying the definition of BONJ to include a category of " suspected BONJ " Stage 0(sa ) where patients have persistent sinus tracts or localized deep periodontal pockets and typical radiographic findings for BONJ but are asymptomatic , and Stage 0(ss ) for those who are symptomatic . - pubmed
We disclosed a case of Page kidney associated with subcupsular renal lymphocele and propose that careful management should be needed in a patient like our case . - pubmed
A new model for blunt liver injuries in the swine . - pubmed
BACKGROUND : To elaborate the impact of new haemostatic agents we developed an instrument for the pressure - controlled induction of blunt liver injuries in a porcine animal model . - pubmed
MATERIALS AND METHODS : A dilutional coagulopathy of 80 % of animal blood volume was induced in 9 anaesthetized pigs . - pubmed
Novel treatment strategies for patients with relapsed classical Hodgkin lymphoma . - pubmed
Although classical Hodgkin lymphoma ( HL ) is considered one of the most curable human cancers , the treatment of patients with relapsed and refractory disease , especially those who relapse after autologous stem cell transplantation , remains challenging . - pubmed
Patients with HL whose disease relapses after stem cell transplantation are rarely cured with current treatment modalities . - pubmed
This review will focus on emerging new treatment modalities that are currently under investigation for patients with relapsed classical HL . - pubmed
We assessed interindividual variability of mean arterial pressure ( MAP ) , CO , and TPR during control conditions in normotensive humans ( n = 40 ) and during normotension and deoxycorticosterone acetate - salt hypertension in Sprague - Dawley rats ( n = 16 ) . - pubmed
The FHC ( fetal human cells ) cell line has been established from normal fetal colonic mucosa . - pubmed
Prostatic disease in the dog ; clinical manifestations and treatment . - pubmed
We have 27 files of patients with torsion of the spermatic cord confirmed to the intervention . - pubmed
The syndrome is frequently misdiagnosed , and patients receive redundant investigations and treatments . - pubmed
Patients are referred finally to a neurologist because of the differential diagnosis of abdominal migraine or abdominal epilepsy . - pubmed
CASE REPORT : We present a 18 - year - old girl with episodic nausea and vomiting attacks who was diagnosed as CVS . - pubmed
Here , we aim to present the clinical features as well as treatment response of a patient with CVS . - pubmed
Experiments on vaccination of human beings against epidemic influenza . - pubmed
Regrettably , in spite of consistent demonstration of a major effect on pain even in patients with deeply infiltrating lesions , progestins are underestimated and dismissed in favour of more scientifically fashionable and up - to - the - minute alternatives . - pubmed
Ischemic stroke in young adults : risk factors , subtypes , and prognosis . - pubmed
BACKGROUND : ischemic strokes occurring in patients younger than 47 years is a relatively rare event and accounts for less than 5 % of all ischemic strokes in western countries . - pubmed
METHODS : in this hospital case series study , we enrolled 192 patients with ischemic stroke , aged 18 to 47 years , all of whom were submitted to a diagnostic protocol . - pubmed
CONCLUSIONS : hypertension , diabetes mellitus , hypercholesterolemia , and smoking were the most common risk factors in our ischemic stroke patients between 18 - 47 years of age . - pubmed
PATIENTS AND METHODS : Ten patients with metaphyseal radius malunions were treated . - pubmed
All patients experienced wrist pain before surgery , which disappeared or decreased after surgery . - pubmed
C. Alberti Prostate carcinoma , even at advanced stages , responds in most patients to androgen deprivation therapies , that are able to exploit the androgen - sensitivity of prostate cancer cells . - pubmed
We prospectively included 150 patients who underwent up to four SWL sessions for renal stones from June 2008 to 2009 . - pubmed
Patients were evaluated for stone expulsion , colic attacks , amount of analgesics and side - effects of alpha - blockers . - pubmed
16 patients on tamsulosin and 21 on doxazosin experienced adverse effects related to postural hypotension . - pubmed
Moreover , 2 ( 4 % ) patients in the tamsulosin group reported ejaculatory complaints . - pubmed
Chrysin protects mice from Staphylococcus aureus pneumonia . - pubmed
aureus pneumonia through histopathology experiments in a mouse model . - pubmed
Over a period of 7 years ( 2003 - 2010 ) , 100 consecutive procedures in 100 patients with chronic suppurative otitis media were performed at the Mansoura University Hospital ( Egypt ) with a minimum follow - up of 12 months ( range 12 - 72 months ) . - pubmed
Does carpal tunnel release provide long - term relief in patients with hemodialysis - associated carpal tunnel syndrome ? - pubmed
BACKGROUND : Carpal tunnel syndrome ( CTS ) is a common complication in patients receiving long - term hemodialysis . - pubmed
In the short - term however , these patients are less likely to have pain relief and restoration of function after carpal tunnel release . - pubmed
However , it is unclear whether patients who have release for hemodialysis - associated CTS have differing persisting relief of symptoms compared with patients with idiopathic CTS . - pubmed
QUESTIONS / PURPOSES : We therefore compared ( 1 ) the severity of pain and level of function in patients who had release for hemodialysis - associated CTS with scores of patients who had release for idiopathic CTS , and ( 2 ) the operation - related complications . - pubmed
METHODS : We retrospectively reviewed 36 patients with CTS who were receiving hemodialysis and 54 patients with idiopathic CTS . - pubmed
Four patients had complications , all with hemodialysis - associated CTS : two had revision carpal tunnel releases and two had delayed wound healing . - pubmed
CONCLUSIONS : Patients with hemodialysis - associated CTS seem to remain impaired , unlike patients with idiopathic CTS , but the majority of them might have much improved CTS - related symptoms at 2 years after carpal tunnel release . - pubmed
Chronic Chagas disease with cardiodigestive involvement and the TcVI infective form of Trypanosoma cruzi . - pubmed
We report a patient with megacolon associated with TcVI infective lineage form of Trypanosoma cruzi . - pubmed
Individuals with cocaine dependence often evidence poor cognitive control . - pubmed
Longitudinal changes in functional disability in Alzheimer ' s disease patients . - pubmed
Participants were evaluated using the Mini - Mental Status Exam ( MMSE ) and the Disability Assessment for Dementia ( DAD ) every six months for < = 2 years . - pubmed
METHODS : We retrospectively studied 55 patients with early HCC ( total 99 nodules ) who underwent initial hepatectomy between 1995 and 2010 . - pubmed
The 5 - year disease - free survival rate was significantly lower in patients with GPC3 - positive early HCC ( 27 % ) than in patients with GPC3 - negative early HCC ( 62 % , P = 0.0036 ) . - pubmed
SUMMARY : Strategies aimed at modifying risk factors for ischemic optic neuropathy associated with prone spinal fusion surgery that are extrinsic to the patient may decrease its incidence . - pubmed
Progression of glomerular filtration rate reduction determined in conscious Dahl salt - sensitive hypertensive rats . - pubmed
Sequential changes in glomerular filtration rate during development of hypertension in the conscious Dahl salt - sensitive rats were determined using a new method for measurement . - pubmed
We conclude that the observed reduction of glomerular filtration rate was a consequence and not a cause of the hypertension and that this noninvasive approach could be used in these conscious Dahl salt - sensitive rats for a longitudinal assessment of renal function . - pubmed
OBJECTIVE : Validate a model of high - fat diet - induced obesity , of low cost , easy reproducibility , that could express characteristics observed in human , and would enable subsequent therapy proposals . - pubmed
The most common specific indication was evaluation of facet joint pain in 70/191 ( 37 % ) patients , and the most common finding was facet joint activity in 106/212 ( 50 % ) patients . - pubmed
It helps identify several potential pain generators , is often used in patients who have a near - contemporaneous MRI , and has an impact on the procedural and/or conservative management in most patients . - pubmed
Altered invariant natural killer T cell subsets and its functions in patients with oral squamous cell carcinoma . - pubmed
However , iNKT cells are not well characterized in patients with oral squamous cell carcinoma ( OSCC ) . - pubmed
It appears that the selectively enriched iNKT subsets and modulation of their function by specific ligand / agonist may be useful for cellular therapy in patients with OSCC . - pubmed
Further , reduced levels of iNKT cells and its DN subset may be used as potential prognostic factors for patients with OSCC . - pubmed
BACKGROUND : This study retrospectively investigated nutritional status , dietetic intervention and intake in Cystic Fibrosis ( CF ) patients before and after lung transplantation ( LTX ) . - pubmed
Patients maintained a low body weight before LTX . - pubmed
Intubation difficulties in a patient with an esophageal foreign body . - pubmed
But they were irrelevant with tumor size , patients ' age and gender ( P>0.05 ) . - pubmed
METHODS : Thirty - two patients with MS were included in a monocentric cohort study . - pubmed
Rebound was associated with severe recurring relapses in 9 % of the patients . - pubmed
Direct deroofing of the lingual cyst and plication of the epiglottis were performed at 3 months of age , and the patient recovered from the respiratory distress . - pubmed
METHODS : The study included 130 patients with RA and 80 healthy controls . - pubmed
PURPOSE : To evaluate the prognosis of " strict " high - risk nodules ( small hepatocellular nodules detected only in the hepatobiliary phase of initial Gd - EOB - DTPA - enhanced MR examination ) in patients with cirrhosis or chronic hepatitis . - pubmed
Taken together , RTL1000 protects against acute injury if applied within a 6 - h time window and improves long - term functional recovery after experimental stroke in DR2 - Tg mice . - pubmed
Sofosbuvir , simeprevir , and ribavirin for the treatment of hepatitis C virus recurrence in human immunodeficiency virus / hepatitis C virus - coinfected liver transplant recipients . - pubmed
Together , our results demonstrate that protracted subversion of immune dynamics contributes to early dissemination and progression of t(14;18)(+ ) precursors and shapes the systemic presentation of FL patients . - pubmed
A total of 90 HD patients were randomly allocated to two 45 - patient groups of oral and video education programs , respectively . - pubmed
Therefore , video education as an effective , inexpensive , simple , and attractive method is recommended for HD patients . - pubmed
We here explored the therapeutic potential of dexamethasone ( Dex)-loaded liposomes for inflammatory liver diseases , using experimental models of acute and chronic liver injury in mice . - pubmed
A total of 102 patients , with a mean age of 54.86 + -13.02 years ( range , 30 - 89 years ) , were included in this study and the incidence of seroma was found to be 22.55 % . - pubmed
Although surgical removal of the primary tumor is considered to be curative , the 5 - year survival rate is no more than 20 % even in patients with clear resection margins ( R0 ) . - pubmed
Cancer metastasis is the primary cause of mortality in cancer patients and is classically viewed as a late event during the progression of the disease , which is supported by the genetic studies used to understand the evolution of pancreatic cancer . - pubmed
In this review , we will discuss the current views regarding pancreatic cancer metastasis with particular emphasis on the epithelial to mesenchymal transition , its influence on the selection of patients for surgical resection and the therapeutic intervention . - pubmed
Neuro - ophthalmological findings in patients with acquired prosopagnosia . - pubmed
Here , we report a spontaneous recessive mouse mutation that causes progressive cerebellar granule cell death and peripheral motor axon degeneration . - pubmed
MATERIALS AND METHODS : 33 strains of Vibrio cholerae eltor O1 and V. - pubmed
Cucumber ( Cucumis sativus L. ) possesses unique attributes useful for organellar genetics , including differential transmission of the three plant genomes ( maternal for plastid , paternal for mitochondrial , and bi - parental for nuclear ) , a relatively large mitochondrial DNA in which recombination among repetitive motifs produces rearrangements , and the existence of strongly mosaic ( MSC ) paternally transmitted phenotypes that appear after passage of wild - type plants through cell cultures and possess unique rearrangements in the mitochondrial DNA . - pubmed
METHODS : Ten embalmed human cadavers were selected . - pubmed
Long non - coding RNAs ( lncRNAs ) are emerging as key molecules in human cancer genesis and progression , including prostate cancer . - pubmed
METHOD : This retrospective study includes 70 patients with SOM who underwent surgery between 1995 and 2012 . - pubmed
In addition , 14 % of patients experienced persistent pain at the location of the iliac harvesting site . - pubmed
Hippocampal neuronal degeneration in the traumatic brain injury mouse : non - trivial effect of scalp incision . - pubmed
OBJECTIVES : In experimental models of traumatic brain injury ( TBI ) , posttraumatic hippocampal neuronal degeneration in the cornu ammonis 1 ( CA1 ) , and/or the cornu ammonis 3 ( CA3 ) regions are regarded as the most notable phenotypic appearances relating to the pathophysiology of human post - concussion syndrome . - pubmed
The frequencies and reasons of appearance of hippocampal neuronal degeneration in mice with TBI and/or sham are not clear . - pubmed
METHODS : We compared the frequencies of hippocampal neuronal degeneration among three groups : TBI ( mice with external force impact performed by Marmarou 's weight drop model after scalp incision ) , sham ( mice with scalp incision alone ) , and control ( mice with neither external force impact nor scalp incision ) , using hematoxylin and eosin stain in day 6 ( n = 5 in each group . ) - pubmed
Careful interpretation is needed concerning hippocampal neuronal degeneration induced by a weight drop device observed in mice with TBI . - pubmed
2,3,7,8 - Tetrachlorodibenzo - p - dioxin ( TCDD ) increases necroinflammation and hepatic stellate cell activation but does not exacerbate experimental liver fibrosis in mice . - pubmed
The goal of this study was to determine how TCDD impacts HSC activation in vivo using a mouse model of experimental liver fibrosis . - pubmed
To elicit fibrosis , C57BL6 / male mice were treated twice weekly for 8weeks with 0.5ml / kg carbon tetrachloride ( CCl4 ) . - pubmed
PATIENTS AND METHODS : A retrospective review of medical records of patients with orbital cellulitis from January 2008 to December 2014 was conducted . - pubmed
Orbital cellulitis was a unilateral occurrence in 38 ( 90.5 % ) patients . - pubmed
Trauma and sinusitis were the common predisposing causes in 20 ( 47.6 % ) and 6 ( 14.3 % ) patients , respectively . - pubmed
Postmortem tissue from 79 individuals was evaluated , including cognitively intact " young " individuals aged younger than 60 years ( range , 33 - 57 years ) , cognitively intact " aged " individuals aged older than 60 years ( range , 61 - 96 years ) with no known neurological disease , and individuals older than 60 years ( range , 61 - 105 years ) of age with a clinical history of AD confirmed by histopathological evaluation . - pubmed
Forty - eight patient samples ( 10 young , 20 aged , and 18 with AD ) underwent histological analysis . - pubmed
Sixty patient samples underwent Western blot analysis ( 15 young , 24 aged , and 21 with AD ) . - pubmed
Objective of this study is to assess the kind and the effectiveness of the most suitable treatment in the apophyseal and epiphyseal knee lesions occurring in the adolescents . - pubmed
MATERIALS AND METHODS : From 2006 to 2011 , were treated 41 patients ( 34 M-7 F ) between the ages of 10 and 15 , with a diagnosis of traumatic knee injury caused by sports activities . - pubmed
METHODS : Regularly cycling women and men without obesity underwent a crossover 6 - hour infusion study over four visits . - pubmed
Rat islets exhibit active transport of MI , although the mechanism involved remains elusive . - pubmed
In corroboration , chronic MI treatment improved the disease phenotypes of diabetic rats and islets . - pubmed
Children with cerebral palsy may have raised lead levels , further impairing their residual cognitive motor and behavioral abilities . - pubmed
Aims and Objectives : To measure blood lead levels in children with cerebral palsy and compare them with healthy neurologically normal children . - pubmed
Participants : Cases comprised 34 children with cerebral palsy , and controls comprised 34 neurologically normal , age- and sex - matched children . - pubmed
Among children with cerebral palsy , 19 ( 55.88 % ) children had blood lead levels & gt;=5 microg / dL. - pubmed
Lead levels in children with pica were 12.33 + - 10.02 microg / dL in comparison to children with no history of pica , 6.70 + - 4.60 microg / dL ( P = .029 ) . - pubmed
Conclusion : In our study , blood lead levels are raised in children with cerebral palsy . - pubmed
METHODS : Nine patients with untreated , biopsy - proven large hepatic metastases ( minimum diameter of 3 cm ) were included . - pubmed
Genome Sequences of Three Novel Isolates of Human Parainfluenza Virus 2 Associated with Acute Respiratory Infection . - pubmed
This information should be helpful to physicians in the treatment of LBP patients . - pubmed
Re : Low - Intensity Shockwave Therapy Improves Hemodynamic Parameters in Patients with Vasculogenic Erectile Dysfunction : A Triplex Ultrasonography - Based Sham - Controlled Trial . - pubmed
Methods : A retrospective chart review between January 1 , 2008 and October 30 , 2015 of patients with biopsy - confirmed lymphocytic , collagenous , or microscopic colitis was conducted . - pubmed
Symptom exacerbations were documented during therapy for 19 % of patients ; therapy changes resulted in good response . - pubmed
Determination of dehydroepiandrosterone and its biologically active oxygenated metabolites in human plasma evinces a hormonal imbalance during HIV - TB coinfection . - pubmed
To our knowledge , this represents the first report of their simultaneous measurement in HIV - TB individuals and the comparison with healthy donors , obtaining statistically higher plasma levels of DHEA , AET and 7 - oxo - DHEA in patients . - pubmed
Between June 2015 and December 2016 , a total of 1268 AHA cases were documented , and 601 cases ( 47.4 % ) were co - infected with HIV ; the majority of whom were MSM ( 98.4 % ) . - pubmed
Each AHA case was matched to two HIV - infected controls without AHA reported in the NDSS on age ( + - 5 years ) , risk factor of HIV infection , HIV diagnosis date ( + - 30 days ) and county / city of residence at HIV diagnosis . - pubmed
Three hundred forty - three HIV / AHA cases were matched to 686 controls . - pubmed
HIV / AHA cases were centralized in northern and central metropolitan areas and HIV - infected MSM with a recent history of sexually transmitted diseases in Taiwan . - pubmed
We recommend surveillance of associated behavioural and virologic characteristics and HAV counselling and testing for HIV - infected men . - pubmed
Omega-3 supplementation effects on body weight and depression among dieter women with co - morbidity of depression and obesity compared with the placebo : A randomized clinical trial . - pubmed
PURPOSE : We aimed to evaluate the effects of the omega-3 supplementation on body weight and depression among women with co - morbidity of depression and obesity seeking weight reduction compared with the placebo . - pubmed
METHODS : Sixty five patients with co - morbidity of depression and overweight / obesity ( BMI & gt;= 25 ) signed the informed consent form and enrolled into this 12 - week double - blind , placebo - controlled randomized clinical Trial . - pubmed
CONCLUSION : Based on our findings omega-3 capsule as a safe over - the - counter supplement might be helpful in reducing the signs of depression and also body weight in patients with co - morbidity of depression and obesity . - pubmed
The article presents an algorithm for prevention and emergency care for a patient with dental needle fracture during mandibular block . - pubmed
METHODS : For this study , 213 nulliparous women who planned vaginal delivery were enrolled and assessed daily until they completed three outcomes : ( 1 ) pain resolution ; ( 2 ) opioid cessation ; and ( 3 ) self - assessed functional recovery to predelivery level . - pubmed
Complexes Ir1 - Ir5 acted as in vitro photodynamic therapy ( PDT ) agents toward human SK - MEL-28 melanoma cells when activated with visible light , with submicromolar photocytotoxicity and phototherapeutic indices ranging from 20 to almost 300 . - pubmed
METHODS : This is a retrospective cohort study of all lung transplant recipients who developed airway stenosis and who were treated with MMC over 4 years . - pubmed
RESULTS : Eleven lung transplant recipients , with airway stenosis were included in our study , who required recurrent balloon dilation , despite airway stents in place in 73 % of these patients . - pubmed
The primary goal of HCV therapy is the long - term elimination of HCV from the blood to reduce the risk of HCV associated complications and death . - pubmed
OBJECTIVE : The purpose of this article is to review the most commonly used tumor markers in abdominal and pelvic tumors , describe their limitations and explain how to use them in the context of known cancer in order to optimize multidisciplinary care of oncologic patients . - pubmed
However , radiologists should also be aware of the limitations of the most commonly used tumor markers and they should not be used solely , but interpreted in conjunction with diagnostic imaging , clinical history and physical examination that will help optimize the multidisciplinary care and management of oncologic patients . - pubmed
This particulate breast cancer vaccine was prepared by spray drying technique and utilized murine breast cancer whole cell lysate as a source of tumor - associated antigens . - pubmed
Upon challenge with live murine breast cancer cells , the vaccinated animals showed five times more tumor suppression than the control animals confirming the immune response activation and protection ( p & lt ; 0.001 ) . - pubmed
However , up to 30 % of patients suffer from relapses despite complete B cell depletion . - pubmed
Our data suggest that early escalation of therapy with tocilizumab may lead to stabilization of disease activity in pediatric NMOSD patients who relapse under B cell depletion . - pubmed
Sepsis and AKI were induced by infusion of live Escherichia coli . - pubmed
The risks are especially high for orphans and unaccompanied children who are separated from their families , making them frequently victims of human trafficking , slavery , drug addiction , crime or sexual exploitation . - pubmed
The effects of cognitive reserve on predicting and moderating the cognitive and psychosocial functioning of patients with bipolar disorder . - pubmed
METHODS : One hundred and twenty - five outpatients with BD type I and sixty healthy individuals were recruited . - pubmed
All participants were assessed with a neuropsychological battery examining attention and processing speed , working memory , visual memory and executive functioning , the Global Assessment of Functioning scale and the Cognitive Complaints in Bipolar Disorder Rating Assessment . - pubmed
RESULTS : Patients with bipolar disorder presented with worse cognitive performance and psychosocial functioning than healthy controls . - pubmed
METHODS : We report for the case of a 10 - year - old male patient who was diagnosed with Cavernous Angioma in Posterior Sagittal Sinus . - pubmed
This study aimed to clarify the clinical significance of TEVAR in esophageal cancer patients . - pubmed
RESULTS : Of the 41 patients identified , 20 patients underwent TEVAR for hemorrhage or impending hemorrhage from the esophagoaortic fistula , while 21 patients underwent TEVAR as preoperative prophylaxis . - pubmed
CONCLUSION : TEVAR is an efficacious modality to control a life - threatening hemorrhage from esophagoaortic fistula and helps to prolong the survival of patients with locally advanced esophageal cancer invading the aorta . - pubmed
These genes were overexpressed in Escherichia coli strains previously engineered to produce different carotenoids . - pubmed
Maximum tumor diameter is associated with event - free survival in PET - negative patients with stage I / IIA Hodgkin lymphoma . - pubmed
METHODS : We retrospectively identified and reviewed the charts of 31 patients with intraparenchymal brain metastases from prostate adenocarcinoma seen at our institution from 2008 to 2018 . - pubmed
RESULTS : Among all patients with brain metastases , the proportion originating from prostate adenocarcinoma was 0.86 % . - pubmed
Patients had concurrent metastases to bone ( 100 % ) , lung ( 48 % ) , and liver ( 35 % ) . - pubmed
All patients died of advanced , systemic disease and not of their intracranial disease . - pubmed
These data enable treating physicians to appropriately counsel their patients with prostate adenocarcinoma brain metastasis . - pubmed
The author reports a retrospective personal series of patients managed over a seven - year period with a nearly unchanged surgical strategy implementing most of known measures for capsular contracture prevention . - pubmed
Of the patients in the revision cohort , 44.3 % were reoperated on because of previous capsular contracture . - pubmed
Toxicity ( > = grade 3 ) in 85 evaluable patients included hypertension ( n=37 ) , neurological changes ( n=2 ) , anorexia ( n=2 ) , infections ( n=9 ) , wound dehiscence ( n=2 ) , DVT / PE ( n=2 ) , and colonic perforation ( n=1 ) . - pubmed
CONCLUSIONS : Bevacizumab combined with vorinostat did not yield improvement in PFS , OS or clinical benefit compared with bevacizumab alone nor a clinical benefit in adults with recurrent GBM . - pubmed
This trial is the first to test a Bayesian adaptive design with adaptive randomization and Bayesian continuous monitoring in patients with primary brain tumor and demonstrates the feasibility of using complex Bayesian adaptive design in a multicenter setting . - pubmed
Structural Changes in the Lungs and Liver of Mice with Experimental Tuberculosis Treated with Liposome - Encapsulated Dextrazide . - pubmed
Efficacy of a foot - and - mouth disease vaccine against a heterologous SAT1 virus challenge in goats . - pubmed
Goats are susceptible to infection with foot - and - mouth disease virus ( FMDV ) , but their role in the epidemiology of the disease and response to vaccination is poorly understood . - pubmed
In this study , we evaluated the efficacy of a pentavalent FMD vaccine in goats against heterologous challenge with a pool of field SAT1 FMDV . - pubmed
OBJECTIVES : As Chlamydia trachomatis ( CT ) and Neisseria gonorrhoeae ( NG ) are the most commonly reported STIs in Belgium and the majority of women infected are asymptomatic , targeted screening of patients in specified risk groups is indicated . - pubmed
Cadophora luteo - olivacea is the most prevalent Cadophora species associated with Petri disease and esca of grapevine . - pubmed
A neuropsychologically - based intervention with increased follow - up support for employed women with multiple sclerosis : a pilot randomized controlled trial . - pubmed
OBJECTIVE : To evaluate feasibility and acceptability of a neuropsychologically - based vocational intervention with increased follow - up support for women with multiple sclerosis . - pubmed
PARTICIPANTS : Forty - nine employed women with multiple sclerosis meeting criteria on measures of cognitive dysfunction ( Symbol Digit Modalities Test ) , fatigue ( Fatigue Severity Scale ) , and/or depression ( Beck Depression Inventory / Patient Health Questionnaire ) . - pubmed
Prevention of DoxDHCer accumulation in worms and in mouse hearts resulted in decreased anoxia - induced injury . - pubmed
MATERIALS AND METHODS : Twenty - eight males with obesity were randomly allocated to an experimental group ( EG , n=14 ) or a control group ( CG , n=14 ) . - pubmed
BACKGROUND : Our Cystic Fibrosis ( CF ) Center initiated a Quality Improvement ( QI ) project in November 2017 with the goal of improving our patients ' Forced Expiratory Volume in One Second ( FEV1 ) percent predicted ( pp ) and continued for 1 year . - pubmed
Our specific aim was to increase the relative mean FEV1 pp by 5 % in 12 months for CF patients 6 - 21 years old with FEV1 < = 80 pp . - pubmed
Fluorescent NPs have great potentials in targeted theranostics including cancer imaging , immunoassay based cells , proteins and bacteria detections , imaging - guided surgery and therapy . - pubmed
MATERIAL AND METHODS : Patients with severely atrophic maxillae were classified into two groups according to the use of CBCT- or MSCT - guided navigation system . - pubmed
Colistin - induced nephrotoxicity occurred in 45.71 % of the patients , of whom 40.6 % were at Risk , 21.9 % at Injury , and 37.5 % at Failure according to RIFLE criteria . - pubmed
In patients who developed AKI , the average total colistin dose received before AKI was 4.4 mg / kg / day . - pubmed
Streptococcus gordonii infectious endocarditis presenting as a neurocysticercosis mimic - A rare manifestation . - pubmed
For patient diagnosed as neurocysticercosis , clinical follow - up is recommended and presence of systemic symptoms should be red flags for another underlying disease . - pubmed
Better molecular characterization of the disease has led to the rapid improvement of personalized medicine and the prompt delivery of targeted therapies to patients with NSCLC . - pubmed
Additionally , the results of ongoing clinical trials with novel - generation TKI will provide more evidence on the best sequence in the treatment of ALK - positive NSCLC patients . - pubmed
Provitamin A - biofortified maize could contribute to the alleviation of vitamin A deficiency ( VAD ) , which is prevalent in sub - Saharan Africa due to a high consumption of starchy , maize - based diets . - pubmed
Autopsy Proven Pulmonary Mucormycosis Due to Rhizopus microsporus in a Critically Ill COVID-19 Patient with Underlying Hematological Malignancy . - pubmed
Effect of various protein diets on growth , renal function , and survival of uremic rats . - pubmed
In controls fed ad lib , weight and length gain were better with high protein diets , whereas they were inversely related to the diet protein content in uremic rats . - pubmed
We report the case of a young female patient who developed an acute polyradiculoneuropathy when she recommended intravenous heroin after four years abstinence . - pubmed
Lower limit of cerebral blood flow autoregulation in experimental renovascular hypertension in the baboon . - pubmed
The effect of chronic renovascular hypertension on the autoregulation of cerebral blood flow was studied in anesthetized baboons . - pubmed
Six baboons with renal hypertension of 8 - 12 weeks ' duration were compared with six normotensive controls . - pubmed
In the chronically hypertensive baboons cerebral blood flow autoregulated until the mean arterial pressure had decreased to the range of 75 - 89 mm Hg . - pubmed
Therefore , the lower limit of autoregulation of cerebral blood flow was shifted to higher absolute levels of mean arterial pressure in baboons with chronic renovascular hypertension presumably due to adaptive changes in the cerebral circulation . - pubmed
Unexplained pelvic distress or pain was observed in the 4 patients of this report ( 3 women and 1 man ) , and also in 6 other patients during a 10 - year period of neurologic practice . - pubmed
It is suggested that this may be a valid entity and that , as with trigeminal neuralgia and postherpetic neuralgia , it is truly limited to aged patients . - pubmed
It may be possible in the future to develop strategies for patients with GI cancers that will be based upon hormonal manipulation in a manner similar to current strategies that are at present employed in the treatment of patients with breast cancer . - pubmed
Recently , it was suggested that the role of hyperinsulinemia on the hypertensive mechanism of essential hypertension might be related to renal sodium handling and sympathetic nerve activity , especially in obese hypertensive patients . - pubmed
Molecular hybridization with cloned fragments of tick - borne encephalitis ( TBE ) virus cDNA in acute and chronic TBE infection . - pubmed
Recombinant plasmid DNA was used as a probe to detect tick - borne encephalitis ( TBE ) virus RNA during incubation period , acute disease and persistent infection of syrian hamsters . - pubmed
In addition , electron microscopic findings in hamster brain confirmed the hypothesis that TBE virus persistence was accompanied by formation of virus - specific structures but impaired virion maturation . - pubmed
This multicenter trial had a sample size goal of 2,220 patients between 21 and 79 years of age who had recently sustained a myocardial infarction and who have an ejection fraction determined by radionuclide ventriculogram ( RVG - EF ) of less than or equal to 40 % . - pubmed
In addition to conventional therapy , patients were randomly assigned to captopril or placebo therapy commencing within 3 - 16 days following their myocardial infarction . - pubmed
Ten patients requiring a cardioverter - defibrillator for recurrent sustained ventricular tachycardia ( five patients ) or aborted sudden cardiac death ( five patients ) were evaluated for implantation of this lead system . - pubmed
In 10 open - chest dogs on cardiopulmonary bypass , the hearts underwent 30 minutes of normothermic global ischemia followed by one hour of multidose hypothermic ( 4 degrees C ) , hypocalcemic ( 0.3 mmol / L ) blood cardioplegia . - pubmed
Here we demonstrate that a high proportion of sperm obtained from certain strains of + /t mice undergo a premature acrosome reaction under in vitro capacitation conditions . - pubmed
They show no phenotypic correlates of malignancy in vitro and produce tumors in syngeneic Fischer rats after long latency periods . - pubmed
In patients with coronary disease , we are used to observe a wide variety of ST segment , T wave and sometimes U wave abnormalities . - pubmed
The data on anatomical connections , injury consequences , summate and unit activity records may be represented as a chain of events running in sequence and in parallel in the brain of higher mammals . - pubmed
Development in normal and hypothyroid animals . - pubmed
All the nervous structures of the cochlea were , however , stained at the end of the first postnatal month , as in normal animals , despite the irreversible complete deafness . - pubmed
Combined chronic toxicity and carcinogenicity studies of morpholine oleic acid salt in B6C3F1 mice . - pubmed
The male mice given 0.25 % MOAS had a significantly reduced incidence of hepatocellular carcinoma in comparison with the control group and this trend was indicated also in the 1.0 % group . - pubmed
Although high concentrations were found in many patients with GU ( P less than 0.01 ) , similar concentrations were found in many patients with radiologically non - functioning gallbladders containing gallstones ( NFG ) ( P less than 0.01 ) and also after cholecystectomy ( AC ) ( P less than 0.01 ) . - pubmed
Since patients with cholelithiasis or after cholecystectomy are not known to have an increased incidence of gastric ulceration , the significance of duodenogastric reflux in the aetiology of gastric ulcers must be questioned . - pubmed
[ Therapeutic effect of lipids from the Far Eastern sardine ( Sardinops sagax melanostica ) in experimental hypercholesterolemia in rats ] . - pubmed
Hypercholesterolemia was experimentally induced in rats which received diets with a high fat content ( 66 % calories ) and cholesterol loading ( 2.5 % of ration ) . - pubmed
Our study was carried out to clarify the changes in granulocyte functions and circulating immune complexes in 32 children with Kawasaki disease . - pubmed
Patients were divided into two groups , those with or without coronary aneurysm . - pubmed
[ Comparison of cardiomegalies developing during different periods in the postnatal development of the rat -- various morphological and biochemical parameters ] . - pubmed
Nursing care of patients with cancer of the head and neck . - pubmed
Progesterone synthesis in the pure trophoblasts of human choriocarcinoma . - pubmed
An acute low oral dose ( 2 mg ) of bromocriptine was administered in a randomized double blind fashion to 11 chronic symptomatic mediated schizophrenic patients . - pubmed
These results suggest a need for further replication in a larger study population and a need for controlled studies with chronic administration of low dose bromocriptine in chronic medicated schizophrenic patients . - pubmed
Reflex cardiovascular responses to chemoreceptor stimulation in conscious dogs with cardiac hypertrophy . - pubmed
When respiration was controlled to eliminate pulmonary inflation reflex activation , the late CCRA - induced increase ( P less than 0.01 ) in right coronary resistance was still found to be depressed ( P less than 0.01 ) in the RV hypertrophy group ( 1.11 + /- 0.20 mmHg X ml-1 X min ) compared with normal dogs ( 3.65 + /- 0.75 ) . - pubmed
In contrast to the depressed right coronary vasoconstriction , the CCRA - induced alpha - adrenergic constriction ( P less than 0.01 ) of the iliac arterial vascular bed was similar in both groups , and the cholinergic increase ( P less than 0.01 ) in cardiac cycle length was enhanced ( P less than 0.01 ) in the RV hypertrophy group compared with normal dogs.(ABSTRACT TRUNCATED AT 250 WORDS ) - pubmed
Effects of aminoglutethimide on delta 5 - androstenediol metabolism in postmenopausal women with breast cancer . - pubmed
Aminoglutethimide plus hydrocortisone ( " medical adrenalectomy " ) has been used to treat postmenopausal women with metastatic breast cancer . - pubmed
We studied delta 5 - androstene-3 beta , 17 beta - diol metabolism in postmenopausal women with breast cancer before and during aminoglutethimide - plus - hydrocortisone therapy , utilizing the constant infusion technique . - pubmed
Neutron and neutron - boost irradiation of soft tissue sarcomas : a 4.5 year analysis of 139 patients . - pubmed
A 4.5 year analysis of neutron and neutron - boost therapy is presented for 139 patients with soft tissue sarcomas . - pubmed
Advanced renal failure in patients with sickle cell anemia : clinical course and prognosis . - pubmed
Advanced renal failure occurred in nine adult sickle cell disease patients . - pubmed
Eight patients had homozygous SS disease , one had sickle cell thalassemia . - pubmed
Angina pectoris , hyperkalemia , and severe anemia complicated chronic dialysis , suggesting that early transplantation should be considered for sickle cell anemia patients with renal failure . - pubmed
The clinical and radiological features of five patients with renal hydatid disease communicating with the collecting system are described . - pubmed
Haemodynamic effects of calcium chloride administered intravenously to patients with and without cardiac disease during neurolept anaesthesia . - pubmed
No good correlation existed between the inhibition of bone resorption measured in vitro on calvaria and that seen in vivo on rat tibiae metaphyses . - pubmed
Perfused rat hindlimb wound model : lambda - carrageenan induced . - pubmed
We established an isolated perfused rat hindlimb wound model using intramuscular injections of lambda - carrageenan . - pubmed
Wound and control hindlimbs of 24 - h fasting anesthetized ( phenobarbital sodium , 5 mg/100 g body wt ) rats were perfused for 60 min ( 10 ml / min ) with media containing 10 mM glucose and physiological levels of amino acids . - pubmed
From 1968 to January 1 , 1977 , 44 patients with initially unresectable colorectal carcinoma were treated with preoperative radiotherapy and surgery . - pubmed
Although prospective studies of defibrillator shock overdose can not be performed in man , the therapeutic indices of various defibrillating current waveforms can be measured in animals . - pubmed
We determined the ratios TD50 / ED50 and LD50 / ED50 ( where TD50 = median " toxic " or damage - inducing dose , ED50 = median effective or defibrillating dose , and LD50 = median lethal dose ) as measures of the therapeutic index for damped sine wave defibrillator shocks in dogs . - pubmed
These data indicate a reasonable margin of safety for damped sine wave defibrillator shocks in dogs , and are consistent with reported incidences of suspected shock - induced damage in humans . - pubmed
Dichloroacetylene ( DCA ) shows pronounced nephrotoxic effects in several animal species and is neurotoxic in humans . - pubmed
METHODS : We tested this tumor marker in 35 patients of gastric cancer , 13 patients of hepatoma , 13 patients of colon cancer , 8 patients of lung cancer , and 22 patients without malignancy ( 4 of acute pancreatitis , 10 of benign gastric ulcer and 8 normal subjects ) between July and December 1991 . - pubmed
Six tumor markers were assessed at the same time in 32 patients of gastric cancer . - pubmed
The purpose of our study was to determine the biological effect of selenium on growth of rat glioma and human glioblastoma cell lines . - pubmed
An antiproliferative effect of selenium was found in two cell lines , which was more effective on human A172 glioblastoma and less effective on rat C6 glioma . - pubmed
An ongoing phase I / II trial in patients with chemotherapy - naive metastatic breast cancer ( one adjuvant chemotherapy regimen is allowed ) uses a 3 - hour infusion of paclitaxel ( Taxol ; Bristol - Myers Squibb Company , Princeton , NJ ) 90 mg / m2 followed by a 3 - hour infusion of cisplatin 60 mg / m2 every 2 weeks given with standard premedications . - pubmed
Eighteen patients are evaluable for toxicity . - pubmed
In order to develop a rapid method for the diagnosis of human brucellosis , results of the ELISA test performed on dried whole blood spotted on filter paper were compared with those of the same test carried out on the serum of the same 160 subjects . - pubmed
Identification of specific antigens of Pseudomonas pseudomallei and evaluation of their efficacies for diagnosis of melioidosis . - pubmed
All antigens were used for detecting antibody in sera from patients with septicemic melioidosis by indirect enzyme - linked immunosorbent assay . - pubmed
Eight patients suffering from unilobar Caroli ' s disease underwent liver resection during a period of six years . - pubmed
Despite the availability of free or low - cost public sector human immunodeficiency virus ( HIV ) health - care services , important inequities in utilization exist . - pubmed
Eye movement dysfunction vs. language delays in migrant children . - pubmed
The case histories are reported of two patients with systemic lupus erythematosus ( SLE ) who developed fatal neurological involvement , each presenting with cerebellar and brainstem signs . - pubmed
Two women ( 4.8 % ) had thyroid function test abnormalities observed at screening , three ( 7.3 % ) had a spontaneous miscarriage , and eight ( 19.5 % ) women were noncompliant with follow - up . - pubmed
A permanent ischemia leading to cerebral infarction was induced after microsurgical exposure and occlusion of the internal carotid , anterior , and middle cerebral arteries in the rabbit . - pubmed
Abnormalities of chromosome 22 in human brain tumors determined by combined cytogenetic and molecular genetic approaches . - pubmed
Nevertheless , discrepancies between the cytogenetic and molecular findings were observed in several cases , suggesting that the use of both methodologies in combination might provide key information on the incidence and extent of the abnormalities involving chromosome 22 in human brain tumors . - pubmed
Therefore a study in 8 patients suffering from allergic rhinitis was conducted . - pubmed
SUBJECTS AND DESIGN : Patients with uncomplicated essential hypertension ( n = 36 ) with a diastolic blood pressure of 95 - 115 mmHg were studied . - pubmed
METHODS : In a retrospective study , we looked at the records of 76 consecutive patients ( 86 eyes ) presenting with epiphora over a period of 2 years ( January 1993 to December 1994 ) . - pubmed
CASE REPORT : An HIV - infected man developed cutaneous leishmaniasis and disseminated histoplasmosis with buccal lesions concomitantly . - pubmed
The spheroid model of culture is a good opportunity to study a resistance type which looks close to the tumour resistance found in vivo in mice and in patients . - pubmed
UNLABELLED : To establish the influence of nonsteroidal anti - inflammatory drugs ( NSAIDs ) on the clinical course of upper gastrointestinal bleeding ( UGIB ) , we designed a longitudinal cohort study to assess the effect of prior use of these drugs on several outcome variables in patients with UGIB . - pubmed
RESULTS : 164 ( 46.6 % ) of 352 patients with UGIB consumed NSAIDs in the week previous to the onset of bleeding . - pubmed
On endoscopic examination , gastric ulcer was the most frequent lesion in patients with NSAIDs as compared to duodenal ulcer in patients without NSAID use ( p & lt ; 0.0001 ) . - pubmed
We have studied the methylation patterns in two 650 kb double minute chromosomes present in two mouse tumor cell lines , resistant to methotrexate . - pubmed
We measured the whole blood chemiluminescence in 59 patients before and after open surgery ( surgery by a laparotomy ) for gastrointestinal disease . - pubmed
Early postoperative infection was detected in 12 ( 20.3 % ) of the 59 patients . - pubmed
In L3.6pl tumors established in the pancreas of nude mice , systemic therapy with C225 alone and C225 in combination with gemcitabine resulted in growth inhibition , tumor regression , and abrogation of metastasis ; median tumor volume was reduced from 538 to 0.3 and to 0 mm3 , respectively . - pubmed
Effect of polaprezinc on healing of acetic acid - induced stomatitis in hamsters . - pubmed
METHOD : Stomatitis was induced in hamsters by local injection of 30 microL of 10 % acetic acid solution into both cheek pouches . - pubmed
CONCLUSION : Polaprezinc is an effective treatment in this animal model of acetic acid - induced stomatitis . - pubmed
Extrapolating these to humans suggests that the drug has healing effect to severe stomatitis induced by anticancer drug therapy . - pubmed
Moreover , they suggest a novel molecular mechanism for a subset of human malformative syndromes of the CNS . - pubmed
We have used the Friend virus model to determine the basic mechanisms by which the immune system can control persistent retroviral infections . - pubmed
[ Familial complicated optic disc drusen in a child ] . - pubmed
We report a case of a 15 - year - old child with optic disc drusen with known familial inheritance and disc swelling . - pubmed
Glibenclamide effects on reperfusion - induced malignant arrhythmias and left ventricular mechanical recovery from stunning in conscious sheep . - pubmed
INTRODUCTION : Sulfonylureas have been associated with a high incidence of cardiovascular death in diabetic patients treated with these drugs . - pubmed
OBJECTIVE : The purpose of this study was to assess whether glibenclamide elicits protection on postischemic myocardial functional recovery ( stunning ) and against reperfusion - induced arrhythmias in a conscious sheep model . - pubmed
Cervical phrenic nerve block for intractable hiccups in cancer patients . - pubmed
RESULTS : By 8 weeks of age , control db / db mice developed hyperglycaemia ( fasting : 10.4+/-0.5 mmol / l ) , hyperinsulinaemia and impaired glucose tolerance . - pubmed
METHODS : 34 patients , who after isolated coronary bypass procedure developed non - Q or Q wave infarction were selected for the study . - pubmed
The study was conducted retrospectively and included patients with stable , unstable , and postinfarction angina without preoperative enzymatic evidence of ischemic injury and with technically noncomplicated coronary bypass grafting . - pubmed
RESULTS : Most patients in both groups had triple - vessel disease ( 10 of 12 patients group A ; 17 of 22 patients group B ) , all patients received complete revascularization ; 7 of 12 patients in group A and 5 of 22 patients in group B had significant or critical left main stem stenosis . - pubmed
The aim of the present study was to identify treatment - related factors that might be associated with the transition of secondary hyperparathyroidism to tertiary hyperparathyroidism in patients with X - linked hypophosphatemic rickets . - pubmed
DESIGN : Thirteen patients with X - linked hypophosphatemic rickets and secondary or tertiary hyperparathyroidism were included in the study . - pubmed
RESULTS : Two patients developed tertiary hyperparathyroidism and 11 patients secondary hyperparathyroidism during the treatment . - pubmed
Patients with tertiary hyperparathyroidism had , on average , earlier onset and longer duration of treatment , higher dose of Pi and longer duration of treatment with very high Pi doses ( & gt ; 100 mg / kg / day ) compared to the 11 patients with secondary hyperparathyroidism . - pubmed
Cephalometric assessment of the posterior airway space in patients with cleft palate after palatoplasty . - pubmed
The purpose of the present investigation was to analyze cephalometric alterations between patients with cleft palate and a noncleft control group in an obstructive sleep disordered breathing - specific tracing . - pubmed
The cohort included 33 subjects ( 13 females , 20 males ; mean age 12.1 + /- 3.8 years , mean body mass index 17.5 + /- 2.9 kg / m(2 ) ) with surgical closure of a unilateral or bilateral cleft palate and a matched control of noncleft participants . - pubmed
RESULTS : Compared with the controls , patients with cleft palate had a significant narrow anterior - posterior dimension of the pharynx at the level of the maxillary plane and the narrowest width , a more downward hyoid position , and a longer uvula . - pubmed
CONCLUSIONS : Patients with cleft palate appear to present pharyngeal and craniofacial distinctive features that characterize patients with obstructive sleep disordered breathing and differ from those of a noncleft control . - pubmed
Results of valvulotomy for valvular pulmonary stenosis with intact ventricular septum ; analysis of sixty - nine patients . - pubmed
ELECTRON MICROSCOPIC EXAMINATION OF YOSHIDA ASCITES HEPATOMAS . - pubmed
[ Therapeutic action of sterosan - hydrocortisone in various superficial dermatoses , with special reference to the dermatoses caused by Candida ] . - pubmed
The effect of PAP 9704 , a traditional prescription in Korea consisting of Polygala tenuifolia , Acorus gramineus , and Poria cocos at a ratio of 1:1:1 ( dry weight ) , on methamphetamine ( MA)-induced hyperlocomotion was examined in mice . - pubmed
Two patients died without preceding signs of progressive external ophthalmoplegia . - pubmed
Characteristic shear rates preventing adhesion to the bottom plate were around 10 and 1.0 s(-1 ) for the bacteria on glass and the PEO - brush and 36 and 3.4s(-1 ) for the yeast strain on glass and the PEO - brush , respectively . - pubmed
The factors associated with increased mortality during ICU stay included increased patient age , allogeneic transplant , intubation / mechanical ventilation , multiorgan system failure ( MOSF ) , presumed / documented infection , graft - versus - host disease , and higher APACHE and O - PRISM score at ICU transfer . - pubmed
Technical considerations are discussed as well as possible advantages of this approach including decreased blood loss , faster patient recovery and improved visualization . - pubmed
The sequence of the 16S ribosomal RNA gene of the bacterium indicated a phylogenetic position of the strain within the genus Sphingopyxis , and the strain was therefore designated Sphingopyxis sp . - pubmed
Thus , we compared outcomes from the Do Tirofiban and ReoPro Give Similar Efficacy Outcome Trial ( TARGET ) for patients who underwent multivessel versus single - vessel PCI and separately considered the effect of acute coronary syndromes on the results . - pubmed
Safety analysis included in - patient major and minor bleeding . - pubmed
In addition , in a propensity - matched analysis that included 810 patients with acute coronary syndrome , multivessel stenting resulted in numerically more ischemic events than did single - vessel stenting , although this did not reach statistical significance ( hazard ratio 1.32 , 95 % confidence interval 0.85 to 2.05 , p = 0.221 ) . - pubmed
Street heroin induces mitochondrial dysfunction and apoptosis in rat cortical neurons . - pubmed
Thus , we analysed the apoptotic pathways involved in street heroin neurotoxicity using primary cultures of rat cortical neurons . - pubmed
DESIGN : A hospital - based association study on degenerative and vascular dementia patients proven on the basis of clinical profile and MRI . - pubmed
PARTICIPANTS : A group of 107 dementia patients and 162 age- and sex - matched controls from a North Indian cohort participated in the study . - pubmed
Increased NoGo - anteriorisation in first - episode schizophrenia patients during Continuous Performance Test . - pubmed
While it is known that patients with chronic schizophrenia exhibit a significant reduction in NGA , it is unclear whether this also occurs in patients undergoing their first - episode . - pubmed
CONCLUSIONS : Attention was reduced in patients with first - episode schizophrenia , as indicated by more false reactions , prolongation of reaction time , P300 - latencies and by a decrease in P300 - amplitude . - pubmed
Significantly however , the NGA and prefrontal LORETA - sources indicate intact prefrontal brain structures in first - episode schizophrenia patients . - pubmed
SIGNIFICANCE : The results support the idea of a possible new biological marker of first episode psychosis , which may be a useful parameter for the longitudinal measurement of changing prefrontal brain function in a single schizophrenia patient . - pubmed
Brain abscess caused by Nocardia nova . - pubmed
We describe a patient with a brain abscess caused by N. - pubmed
This is the first detailed report of central nervous system infection due to N. - pubmed
Inoculation with the neurotropic JHM strain of mouse hepatitis virus ( JHMV ) into the central nervous system ( CNS ) of mice results in an acute encephalitis associated with an immune - mediated demyelinating disease . - pubmed
Of 20 patients followed - up , nine were alive in remission , two alive in disease , one died of treatment related complication , four died of progressive lymphoma , four died of AIDS related causes . - pubmed
As a substantial portion of the patients remains alive disease free , the impact of HAART on the clinical course of ARL needs further follow - up and evaluation . - pubmed
Some of such proteins could be autoantigens that extend the ocular inflammation in human endogenous uveitis . - pubmed
Six weeks after immunization , the presence of autoantibodies against the retinal proteins in mice with EAU were examined by two - dimensional electrophoresis followed by western blotting ( 2D - WB ) . - pubmed
METHODS : Thirty - one patients with CS DAVFs ( 33 lesions ) underwent TVE . - pubmed
Although patients harboring lesions with a greater coil volume required a longer recovery time , newly developed or aggravated CNP , related to 84.6 % of the lesions , resolved completely . - pubmed
This study examined the efficacy and tolerability of the opioid antagonist naltrexone in adults with kleptomania who have urges to steal . - pubmed
Twenty - five individuals with DSM - IV kleptomania were randomized to naltrexone ( dosing ranging from 50 mg / day to 150 mg / day ) or placebo . - pubmed
Subjects assigned to naltrexone also had greater improvement in overall kleptomania severity ( reflected in the CGI scores ) ( p & lt ; .001 ) . - pubmed
PATIENTS : Patients included 172 consenting HD patients who had been on HD for at least 3 months and were mentally stable . - pubmed
Living donor kidney transplantation ( KT ) is the treatment of choice for end - stage renal disease patients and exhaustive assessment of the potential live kidney donor leads to successful KT in most occasions . - pubmed
OBJECTIVE : We evaluated asthma patients who underwent long - term treatment with a new ICS to determine if they had tooth problems that were related to osteoporosis of the mandible . - pubmed
RESULT : Asthma patients with tooth loss ( n = 36 ) and with caries or other tooth problems ( n = 28 ) were found to have a significantly higher prevalence of osteoporosis in the mandible than those without tooth problems ( n = 17 ; 22.2 % , 7.1 % , 0 % , respectively ; chi(2 ) = 6.34 , p & lt ; 0.05 ) . - pubmed
Hyperhomocysteinemia in levodopa - treated patients with Parkinson ' s disease dementia . - pubmed
Increased Hcy levels have been observed in levodopa - treated patients with PD . - pubmed
We performed a multicenter cross - sectional study on patients with PD with ( PDD ) and without ( PDnD ) dementia and age- and sex - matched healthy controls . - pubmed
We compared Hcy levels in patients with PDD and PDnD and healthy controls , and we performed logistic regression analysis to search for an association between the presence of dementia and increased Hcy levels in PD . - pubmed
Patients with PD ( 121 ) , PDD ( 42 ) , and PDnD ( 79 ) , and age- and sex - matched controls ( 154 ) were enrolled . - pubmed
Hcy levels were higher in patients with PD compared to controls ( 17.5 micromol / L + /- 10.2 vs. 11 + /- 4.1 ; P < 0.00001 ) . - pubmed
Among patients with PD , Hcy levels were higher in the PDD group compared to the PDnD group ( 20.7 micromol / L + /- 12.1 vs. 15.8 + /- 8.5 ; P = 0.002 ) . - pubmed
A 14 - year - old adolescent girl with a diagnosis of recurrent embryonal - botryoidal rhabdomyosarcoma was referred to us . - pubmed
Based on its pathogenesis , in addition to a number of correlative studies , immunotherapy represents a potential therapeutic option for patients with HCC . - pubmed
It has been shown that these suppressor cells mask tumor - specific immune responses in patients with HCC . - pubmed
Different immunotherapeutic approaches including peptide- and dendritic cell - based therapies have demonstrated promising results in patients with HCC . - pubmed
METHODS : Male C57BL/6 mice were subjected to a major burn ( 3rd degree , 25 % TBSA ) or sham treatment . - pubmed
It is a main theme of ophthalmologic research , because retinopathies are common causes of blindness in all age groups : age - related macular degeneration in the elderly , diabetic retinopathy in the middle aged , and retinopathy of prematurity and retinoblastoma in children . - pubmed
OBJECTIVE : To identify functional outcomes that could justify the need for a rehabilitation care program for patients with metastatic epidural spinal cord compression ( MESCC ) and paraplegia . - pubmed
Quantitative trait loci for resistance to fusarium head blight in a Chinese wheat landrace Haiyanzhong . - pubmed
The major QTL on 7D can be used to improve the FHB resistance in wheat breeding programs and add diversity to the FHB resistance gene pool . - pubmed
Amerithrax , the investigation into the anthrax letter attacks , applied high - resolution whole - genome sequencing and comparative genomics to identify key genetic features of the letters ' Bacillus anthracis Ames strain . - pubmed
Patients were evaluated using the anterior knee pain score of Kujala et al . - pubmed
Lipogenic gene expression in abdominal adipose and liver tissues of diet - induced overweight cats . - pubmed
Spinal cord injury with persistent paraplegia occurred in 1/19 ( 5.2 % ) patients . - pubmed
Determinants of warfarin use and international normalized ratio levels in atrial fibrillation patients in Japan . - pubmed
BACKGROUND : Determinants of warfarin use and anticoagulation levels in atrial fibrillation ( AF ) patients have not been clarified thoroughly . - pubmed
Target INR levels for non - valvular AF patients were 1.6 - 2.6 for patients aged & gt;= 70 years and 2 - 3 for patients aged & lt ; 70 years . - pubmed
Those for patients with valvular AF were 2 - 3 . - pubmed
Patients with non - valvular AF and CHADS2 score & gt;= 1 receiving warfarin ( n = 5,614 ) more frequently had permanent AF , congestive heart failure , and stroke or transient ischemic attack ( TIA ) , and had higher CHADS2 scores than those not receiving warfarin . - pubmed
Example plans were generated for 10 of the patients in the study who exhibited significant hypoxia . - pubmed
We created an IMRT plan for each patient with a simultaneous integrated boost ( SIB ) to the hypoxic sub - volumes . - pubmed
Letter : diabetic polyneuropathy and cardiovascular complications in type 2 diabetic patients ( diabetes metab j 2011;35:390 - 6 ) . - pubmed
The aim of this study was to compare the in vitro activity of ethanol , EDTA and levofloxacin ( Levo ) , alone or in combination , on biofilms of Stenotrophomonas maltophilia recovered from patients with catheter - related bloodstream infections ( CRBSIs ) at a university hospital in Argentina . - pubmed
First , 24 and 48 h biofilms were formed in microtitre plates and challenged with 25 or 40 % ethanol for 1 h. Biofilms , of the 14 local isolates and from the reference strain K279a , were eradicated after both treatments as shown by plate counts and the regrowth technique . - pubmed
Leishmania major infection in humanized mice induces systemic infection and provokes a nonprotective human immune response . - pubmed
We show that inflammatory human macrophages get infected with Leishmania parasites at the site of infection . - pubmed
However , the human immune system is not able to prevent systemic infection . - pubmed
Comparable to some Miltefosine treated patients , humanized mice developed severe side effects , which are not detectable in the classical murine model of experimental leishmaniasis . - pubmed
[ Streptococcus suis meningitis in a meat factory employee ] . - pubmed
BACKGROUND : In the Netherlands , Streptococcus suis is a rare cause of meningitis . - pubmed
CASE DESCRIPTION : At the Emergency Department , a 60 - year - old man presented with headache , confusion , fever and nuchal rigidity . - pubmed
CONCLUSION : Particularly people who are in close contact with pigs have an increased risk of S. - pubmed
Rodent model in caries research . - pubmed
The rodent model of dental caries has made fundamental contributions to the understanding of the etiology , pathogenesis , and prevention of this disease . - pubmed
A psychometric validation of two brief measures to assess palliative need in patients severely affected by multiple sclerosis . - pubmed
CONTEXT : Most patient - reported outcome measurement tools in multiple sclerosis ( MS ) are geared toward less severely affected patients . - pubmed
Palliative care outcome measures have not been validated in patients with MS . - pubmed
Twenty - seven patients with diabetic foot ulcers ( foot ulcer group ) , 27 patients without diabetic foot ulcers ( diabetic control group ) and 27 healthy controls were enrolled . - pubmed
SPA appears to be higher in patients with diabetic foot ulcers when compared with patients without diabetic foot ulcers and healthy controls . - pubmed
Clinical factors associated with left ventricular ejection fraction disparity in patients with left ventricular dysfunction undergoing multimodality imaging . - pubmed
In 119 patients with left ventricular dysfunction who underwent both echocardiography and stress testing with nuclear imaging within seven days ( but with significant disparity in reported left ventricular ejection fraction ) , we identified four clinical variables which were associated with left ventricular ejection fraction difference . - pubmed
BACKGROUND : Serum phosphorus control is critical for chronic kidney disease ( CKD ) 5D patients . - pubmed
OBJECTIVE : To establish the efficacy , safety , and tolerability of lanthanum carbonate in CKD 5D patients . - pubmed
CONCLUSION : Lanthanum carbonate is an efficacious and well - tolerated oral phosphate binder with a mild AE profile in hemodialysis and CAPD patients . - pubmed
This agent may provide an alternative for the treatment of hyperphosphatemia in CKD 5D patients in mainland China . - pubmed
Though approximately half of the patients recover , the clinical course is highly variable and some patients develop refractory heart failure and persistent left ventricular systolic dysfunction . - pubmed
Adenovirus ( ADV ) types 4 ( ADV-4 ) and 7 ( ADV-7 ) are presently the major cause of febrile acute respiratory disease ( ARD ) in U.S. military recruits . - pubmed
The primary endpoints were prevention of febrile ARD due to ADV-4 and seroconversion of neutralizing serum antibodies to ADV-7 , which was not expected to circulate in the study population during the course of the trial . - pubmed
It is important to differentiate progressive from nonprogressive precocious puberty to avoid unnecessary treatment for the latter ; if diagnosis is uncertain , the child should be reassessed within several months . - pubmed
Gonadotropin - releasing hormone agonists should be considered only for children with progressive central precocious puberty to prevent short stature . - pubmed
For children with apparent nonprogressive precocious puberty , follow - up every 3 to 6 months between ages 6 and 7 years is recommended to assess for progression . - pubmed
Epidemiology of human leishmaniasis in Greece , 1981 - 2011 . - pubmed
Transcatheter aortic valve replacement ( TAVR ) in patients with systemic autoimmune diseases . - pubmed
[ Fate of the pancreas in the guinea pig after death of the animal ] . - pubmed
Endoscopic finding of RAC ( regular arrangement of collecting venules ) in the angle of stomach suggests lack of infection with H. - pubmed
RESULTS : The percentage of healthy children aged 6 years , who did not have any signs of dental caries manifested with cavity , tooth filling or tooth loss was only 14.4 % . - pubmed
We performed a retrospective analysis on 535 consecutive laryngeal cancer patients submitted to open partial laryngectomy at the Otolaryngology - Head and Neck Surgery Department of Florence University to evaluate a possible correlation between smoking and surgical complications . - pubmed
Patients were grouped in non smokers and smokers and evaluated for airway , swallowing , local and fistula complications by multivariate analysis : 507 ( 95 % ) patients were smokers , 69 % presented supraglottic , 30 % glottic and 1 % transglottic cancer . - pubmed
Mouse models of primary central nervous system lymphomas : tools for basing funding and therapeutic strategies . - pubmed
Indeed , several limitations of human sample present a major obstacle to the identification of the particular microenvironment of the sanctuary sites where these tumor cells grow . - pubmed
In addition , the generally poor overall condition and performance status of patients with PCNSL limit their participation in prospective trials . - pubmed
Therefore , animal models of PCNSL are essential for tumor microenvironment characterization and for antitumor response studying . - pubmed
In this review , we have compiled the B - and T - cell PCNSL mouse models that are used to improve our understanding of the lymphoma microenvironment , tropism and migration and to investigate novel therapeutic strategies . - pubmed
While this will not obviate the use of free tissue transfer , it may add to the surgical armamentarium for aesthetic restoration in the breast cancer patient . - pubmed
RESULTS : Seventeen patients ( mean age 83.95 + -5.84 ) developed retinal pigment epithelium tears . - pubmed
Getting to the heart of the matter : cardiovascular disease in patients with HIV . - pubmed
METHODS : Thirty - six patients , treated with TPA followed up by full fixed appliances , were divided into stable and relapse groups based on the long - term presence or not of relapse . - pubmed
Based on the results obtained with the acaricide - sensitive laboratory strain , acaricides were selected to test against eggs , larvae , and adults of four field populations of T. - pubmed
The chronic toxicity of inorganic Hg - Hg ( II )--through food or soil contaminations was therefore assessed for the snail Cantareus aspersus , a well - recognized soil quality bioindicator . - pubmed
We investigated whether phagocytosis participates in the protection of insects from viral infection using the natural host - virus interaction between Drosophila melanogaster and Drosophila C virus ( DCV ) . - pubmed
Drosophila S2 cells were induced to undergo apoptotic cell death upon DCV infection . - pubmed
To validate the in vivo situation , adult flies were abdominally infected with DCV , followed by the analysis of fly death and viral growth . - pubmed
Furthermore , hemocytes isolated from infected flies contained DCV - infected cells , and preinjection of latex beads to inhibit the phagocytic activity of hemocytes accelerated fly death after viral infection . - pubmed
RESULTS : FTLD patients carrying the D * genotype ( H / D or D / D ) showed greater atrophy in the basal ganglia , bilaterally , compared to H / H carriers ( x , y , z : -22 , -4 , 0 ; T = 3.45 ; cluster size : 33 voxels , x , y , z : 24 , 4 , -2 ; T = 3.38 ; cluster size : 36 voxels ) . - pubmed
Analysis of Local Recurrence Following Proximal Gastrectomy in Patients with Upper Third Gastric Cancer . - pubmed
PURPOSE : Little is known about local recurrence following proximal gastrectomy in patients with upper third gastric cancer . - pubmed
We performed this study to evaluate the long - term results of a proximal gastrectomy , and to analyze the risk factors of local recurrence affecting survival in these patients . - pubmed
MATERIALS AND METHODS : We undertook a retrospective study of 63 patients who underwent potentially curative proximal gastrectomy between 1990 and 1999 , with special reference to local recurrence . - pubmed
RESULTS : During a median follow - up period of 37 months , 25 of the 63 patients ( 39.7 % ) developed a recurrence of cancer , with local recurrence in 15 patients ( 23.8 % ) , the majority of these occurring at the remnant stomach or anastomosis . - pubmed
Reoperation for cure was possible in only 4 patients and most died within the first year following diagnosis of recurrence . - pubmed
We investigated the relationship between RI and cardiac function , and evaluated the utility of RI for predicting cardiac events in patients with CVD . - pubmed
METHODS AND RESULTS : Renal Doppler ultrasonography and echocardiography were performed in a total of 452 patients with CVD . - pubmed
OBJECTIVE : To understand phenotypic and molecular characteristics of patients with clinically " definite " primary lateral sclerosis ( PLS ) in a prospective study . - pubmed
METHODS : Six sites enrolled 41 patients who had pure upper motor neuron dysfunction , bulbar symptoms , a normal EMG done within 12 months of enrollment , and onset of symptoms & gt;=5 years before enrollment . - pubmed
Patients with locally advanced oropharyngeal cancer are at risk for poor outcomes due to the multi - modal nature of treatment and the potential for treatment - related toxicity . - pubmed
AA preferentially affects pigmented hairs , and the hair of patients with AA frequently shows a change in colour when it regrows following an acute episode of AA . - pubmed
BACKGROUND : Metastases are the most common reason of cancer death in patients with solid tumors . - pubmed
Echinococcus granulosus infection in dogs in Sidi Kacem Province ( North - West Morocco ) . - pubmed
Herein we report two patient cases with mesothelioma who received second - line chemotherapy with the combination of cisplatin and the novel compound lurbinectedin . - pubmed
CONCLUSIONS : The mortality rate of nontuberculous mycobacterial disease among HIV - uninfected individuals has increased in the United States between 1999 and 2014 . - pubmed
BACKGROUND : There are a range of opinions on the benefits and thresholds for the transfusion of red blood cells in critically ill patients with traumatic brain injury ( TBI ) and an urgent need to understand the neurophysiologic effects . - pubmed
The aim of this study was to examine the influence of red blood cell transfusions on cerebral tissue oxygenation ( SctO2 ) in critically ill TBI patients . - pubmed
METHODS : This prospective observational study enrolled consecutive TBI patients with anemia requiring transfusion . - pubmed
RESULTS : We enrolled 24 patients with severe TBI , of which five patients ( 21 % ) were excluded due to poor SctO2 signal quality from large subdural hematomas and bifrontal decompressive craniectomies . - pubmed
CONCLUSIONS : The bifrontal method of recording changes in NIRS signal was not able to detect a measurable impact on SctO2 in this sample of patients receiving red blood cell transfusion therapy in a narrow but conventionally relevant , range of anemia . - pubmed
Human respiratory syncytial virus ( RSV ) is an enveloped RNA virus that is the most important viral cause of acute pediatric lower respiratory tract illness worldwide , and lacks a vaccine or effective antiviral drug . - pubmed
A 37 - year - old male patient presented with fever , incomplete paralysis of bilateral legs , and bullous eruptions 8 months after allogeneic transplant . - pubmed
While there is a wide range of neoplastic and non - neoplastic skin diseases for which ALA - PDT is used in adults , there is a knowledge gap when it comes to its use in children . - pubmed
ALA - PDT has been used successfully in children to reduce the number and size of basal cell tumors , inflammatory acne lesions , plantar warts , and linear porokeratoses . - pubmed
ALA - PDT may be an attractive alternative to surgery for children with basal cell nevus syndrome , or to conventional destructive and/or topical methods used for plantar warts or linear porokeratoses . - pubmed
METHODS : Sixty - nine patients with a mean age of 15.3 + - 1.9 years completed a neurocognitive , vestibular / ocular motor , and symptom assessment within 7 days of a diagnosed concussion . - pubmed
Age , pre - treatment sputum smear grading , HIV status and TB disease classification influenced two - month sputum smear non - conversion . - pubmed
Integrated treatment models are effective for early psychosis ( SMD -0.38 , 95 % CI -0.53 to -0.22 ) as long as the patients remain in treatment . - pubmed
In liver transplantation patients , CMV infection and BPAR were closely associated with T cell population changes . - pubmed
The increasing awareness of population , the burden of new types of disease , as well as the recurrence of food scandals have recently launched a scientific and population debate on the contribution of foods items , especially those of animal origin , to the toxic exposure of food producing animals and humans . - pubmed
The rate of acute adverse reactions and contrast - induced nephropathy is lower than in adults . - pubmed
The relationship between nephrogenic systemic fibrosis and gadolinium administration is well established and only a small number of children suffer from this debilitating disorder . - pubmed
The recent finding of gadolinium deposition in the brain of patients with normal renal function has renewed concerns regarding its long - term toxicity . - pubmed
The anti - hyperuricemic effect of epigallocatechin-3 - gallate ( EGCG ) on hyperuricemic mice . - pubmed
This study aimed to evaluate the antihyperuricemic activity of EGCG on hyperuricemic mice . - pubmed
These results presented that EGCG had obvious hypouricemic and renal protective effects on hyperuricemic mice . - pubmed
Pattern onset / offset ERGs to pedestal stimulation may be used to probe simultaneous recording of ERGs with VEPs in order to obtain an assessment of retinal ganglion cell and optic pathway function in patients with less stable fixation . - pubmed
[ Radiofrequency catheter ablation of premature ventricular contractions in children under CARTO3 system : a retrospective study from one single center ] . - pubmed
Objective : To evaluate the clinical effect and summarize the experience of radiofrequency catheter ablation ( RFCA ) for children suffered from premature ventricular contractions ( PVCs ) . - pubmed
Conclusion : RFCA is safe and effective for PVCs in children with high success rate and low recurrence and complication rates . - pubmed
Delayed diagnosis of primary vesicoureteral reflux in children with recurrent urinary tract infections : Diagnostic approach and renal outcomes . - pubmed
RESULTS : A total of 32 children ( female , n=27 : 84.4 % ) with a mean age of 7.67 + -3.34 years at the time of diagnosis of VUR were included in the study . - pubmed
Tc-99mDMSA detected abnormalities in 83.9 % ( 7 with a single scar , 7 with multiple lesions , 12 with reduced kidney function ) of the patients . - pubmed
In 5 patients ( 16 % ) , VUR could not be predicted by US+DMSA scintigraphy ( Grade IV VUR in 3 and Grade III in 2 cases ) . - pubmed
Moreover , our findings can be useful in the identification of genotype to phenotype relationship in patients , and provide future abilities for confirmatory diagnostic testing , prognosis , and predict the severity of PKU patients . - pubmed
These results indicate that repeated exposures to the nerve agent , DFP at doses that are below the threshold for acute toxicity , can result in alterations in myelin structure and persistent decreases in axonal transport in the rodent brain . - pubmed
These observations could explain some of the long - term neurological deficits that have been observed in humans who have been repeatedly exposed to OPs . - pubmed
The control group consisted of 129 patients who underwent open suturing of perforated ulcer followed by conventional treatment in postoperative period . - pubmed
In 129 patients of the control group open suturing of the perforated ulcer and conventional postoperative therapy were applied . - pubmed
CONCLUSION : Laparoscopic treatment of perforated ulcers facilitates application of fast track rehabilitation program in emergency patients . - pubmed
Young Man With Unilateral Neck Swelling . - pubmed
Anti - proliferative activity of these structures was tested in vitro against a panel of five human cancer cell lines , including prostate ( PC-3 ) , colon ( HT-29 ) , leukemia ( CCRF - CEM ) , lung ( HTB-54 ) and breast ( MCF-7 ) . - pubmed
Materials and Methods : In this cross - sectional retrospective study , we analyzed 39 patients who underwent radical orchiectomy due to a testicular cancer ( Group 1 ) and 82 patients on whom varicocelectomy procedure was performed as control group ( Group 2 ) between January 2006 and January 2016 in our clinic . - pubmed
METHODS : Keratinocytes isolated from the skin of healthy subjects ( n = 20 ) and patients with atopic dermatitis ( n = 20 ) as well as HaCaT and PCS-200 - 010 cell were exposed to the 900 MHz electromagnetic field for 60 minutes . - pubmed
Of the 14 patients who had undergone embolization as initial treatment , 5 ( 36 % ) had developed a recurrence within an average of 29.6 months ( range , 2 - 87 ) . - pubmed
None of patients in the surgical group developed recurrence . - pubmed
A multidisciplinary and ordered decision is crucial for the treatment choice to ensure better outcomes , especially for patients with a definite neurologic deficit at diagnosis . - pubmed
CASE PRESENTATION : Patient 1 was a 16 - year - old boy diagnosed with bilateral JOAG and high myopia . - pubmed
Patient 3 was a 35 - year - old man with bilateral JOAG . - pubmed
CONCLUSIONS : This case series describes three patients with concomitant occurrence of JOAG and LHON . - pubmed
Primary outcome variables included comparisons of incidence and 5 - year overall survival in kidney transplant recipients versus nonrecipients after treatment of prostate cancer . - pubmed
Methods : A retrospective analysis was performed on the screening data of elderly women ( & gt;=50 years ) who had examination at cervical lesion clinic in Peking University People 's Hospital and Affiliated Hospital of Guizhou Medical University from January 2013 to January 2014 , with histopathology as the gold standard , to compare screening effectiveness of cervical cytology or HPV detection for elderly women in cervical cancer screening in the two regions . - pubmed
Vitamin D and probiotic co - supplementation affects mental health , hormonal , inflammatory and oxidative stress parameters in women with polycystic ovary syndrome . - pubmed
OBJECTIVE : The aim of this study was to determine the effect of vitamin D and probiotic co - administration on mental health , hormonal , inflammatory and oxidative stress parameters in women with polycystic ovary syndrome ( PCOS ) . - pubmed
Candida albicans and Actinomyces viscosus are prominent microbes associated with dental root caries . - pubmed
We hypothesized that the use of local dental anesthesia with lidocaine with and without epinephrine is safe and does not result in life - threatening arrhythmias in patients with channelopathies . - pubmed
Fifty - six dental procedures were performed in 28 patients ( 18 women , 10 men ) with cardiac channelopathies : 16 ( 57.1 % ) had long - QT syndrome , and 12 ( 42.9 % ) had Brugada syndrome ; 11 ( 39.3 % ) of patients had an implantable defibrillator . - pubmed
In patients with long - QT syndrome , the median corrected QT was higher , from 450.1 to 465.4 ms ( P=0.009 ) at the end of anesthesia in patients in whom epinephrine was used . - pubmed
Conclusions The use of local dental anesthesia with lidocaine , regardless of the use of a vasoconstrictor , did not result in life - threatening arrhythmias and appears to be safe in stable patients with cardiac channelopathies . - pubmed
CONCLUSIONS : Despite the relative economic homogeneity of the cohort , lower education level is associated with increased subclinical atherosclerosis , mainly mediated by the higher and more frequent tobacco consumption . - pubmed
PURPOSE OF REVIEW : This review highlights recent advances in the diagnosis and management of children with heart failure . - pubmed
We emphasize the clinical approach to patient care in the areas of acute decompensated heart failure , chronic heart failure , and failure of the patient with single ventricle physiology . - pubmed
RECENT FINDINGS : Important guidelines regarding the recognition and management of heart failure in children have been proposed and adopted , providing guidance for early recognition and ongoing management . - pubmed
SUMMARY : Improved outcomes in children with heart failure are possible . - pubmed
Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support in a Patient with Panhypopituitarism : A Case Report . - pubmed
METHODS : All consecutive , technical inoperable or residual CTEPH patients receiving bosentan or macitentan , diagnosed in our multidisciplinary team between January 2003 and January 2019 , were included . - pubmed
CONCLUSION : CTEPH patients receiving bosentan or macitentan have improved clinical outcomes till 2 - year follow - up , without significant differences in outcomes between both therapies . - pubmed
Post - Traumatic Endophthalmitis Caused by Oerskovia turbata . - pubmed
Case Report : A patient presented with chronic endophthalmitis that occurred after ocular trauma with organic material and Oerskovia turbata was eventually isolated . - pubmed
Conclusion : This is the first reported patient with endophthalmitis due to O. - pubmed
turbata , a Gram - positive bacillus found in soil that rarely causes human infection . - pubmed
DESIGN : Four stimulation protocols combining 20 and 40 Hz average frequency with either constant frequency trains or with doublet frequency trains ( CFT and DFT ) were applied to the quadriceps of seven adults with SCI and eight able - bodied participants . - pubmed
PARTICIPANTS : Seven individuals with SCI ( 1 female ; age range , 25 + 6 years ) and eight age - matched able - bodied participants ( 1 female ) . - pubmed
The updated CANMAT guidelines recommended the most second - generation antidepressants as first - line treatments for patients with a major depressive disorder ( MDD ) of moderate or greater severity . - pubmed
It is recommended that antidepressant is used with monotherapy in patients with depression . - pubmed
Antidepressants of different types and different mechanisms could be combined to improve the efficacy for patients with treatment - resistant depression ( TRD ) . - pubmed
To prevent the relapse and recurrence of disease , the long - term treatment comprised of acute treatment , consolidation treatment , and maintenance treatment must be considered for all patients . - pubmed
AKI had developed in 47 patients ( 45.6 % ) by the second postoperative day . - pubmed
We retrospectively evaluated patients with operable early - stage NSCLC who elected to receive primary SBRT , examined factors associated with SBRT , and compared overall survival after surgery and SBRT . - pubmed
It can serve as a central component for rheumatological healthcare for patients with RA at various levels . - pubmed
Therefore , we investigated the relationship between pain and angular change of the lower extremity in genu varus patients . - pubmed
Standing whole - lower - leg plain radiographs of 127 legs ( 77 patients ) with > 4 of genu varum were evaluated . - pubmed
Trimeresurus albolabris snakebite treatment implications arising from ontogenetic venom comparisons of anticoagulant function , and antivenom efficacy . - pubmed
Given that coagulotoxicity is the primary serious pathology in T. - pubmed
albolabris envenomations , we conclude that Thai Red Cross Green Tree Pit Viper Antivenom is a valid treatment for envenomations by this species , regardless of age or sex of the offending snake . - pubmed
Characterizing Static and Dynamic Fractional Amplitude of Low - Frequency Fluctuation and its Prediction of Clinical Dysfunction in Patients with Diffuse Axonal Injury . - pubmed
RATIONALE AND OBJECTIVES : Recently , advanced magnetic resonance imaging has been widely adopted to investigate altered structure and functional activities in patients with diffuse axonal injury ( DAI ) , this patient presumed to be caused by shearing forces and results in significant neurological effects . - pubmed
MATERIALS AND METHODS : In this study , static and dynamic fractional amplitude of low - frequency fluctuation ( fALFF ) , an improved approach to detect the intensity of intrinsic neural activities , and their temporal variability were applied to examine the alteration between DAI patients ( n = 24 ) and healthy controls ( n = 26 ) at the voxel level . - pubmed
Then , the altered functional index was used to explore the clinical relationship and predict dysfunction in DAI patients . - pubmed
RESULTS : We discovered that , compared to healthy controls , DAI patients showed commonly altered regions of static fALFF , and its variability was mainly located in the left cerebellum posterior lobe . - pubmed
More important , the increased temporal variability of dynamic fALFF in the left caudate could predict the severity of the Glasgow Coma Scale score in DAI patients . - pubmed
Liver transplantation for fulminant herpes simplex hepatitis in a patient treated with adalimumab for chronic pouchitis . - pubmed
The aim of the current study was to review articles published in the years 2017 - 2018 and create a list of the most important and strongest non - conventional factors that could be used in the future assessment of the prognosis of patients with adenocarcinoma and squamous cell carcinoma of the lung who can not undergo current targeted therapy . - pubmed
The selected molecular factors exhibit the potential to be used in the treatment of patients with specific problematic lung cancer , and may contribute to setting recommendations for the diagnosis , prognosis and treatment of individual patients with lung cancer . - pubmed
Accumulating data from both humans and experimental animal models suggests that PVAT dysfunction is potentially linked to cardiovascular diseases , and associated with augmented vascular inflammation , oxidative stress , and arterial remodeling . - pubmed
Both soil and foliar Se and Si applications significantly alleviated Cd toxicity by regulation of Cd transport genes , as reflected by increased the grain yield and antioxidant enzymes activities , and reduced MDA in wheat tissues . - pubmed
Cinnamaldehyde / eugenol blend did not show any cytotoxic effect ( IC50 > 1000 mug / ml ) in human normal keratinocyte cell line . - pubmed
Facial Morphological Changes Following Denture Treatment in Children with Hypohidrotic Ectodermal Dysplasia . - pubmed
Purpose : The purpose of this study was to characterize the facial morphology of Chinese children with hypohidrotic ectodermal dysplasia ( HED ) and quantify facial changes after prosthetic treatment . - pubmed
Methods : 3 - D facial images of 12 HED children were taken and their facial morphology was compared against 28 healthy controls . - pubmed
Conclusions : The facial morphology of Chinese children with hypohidrotic ectodermal dysplasia differs significantly from healthy children , creating a more concave facial profile . - pubmed
The Relationship between Diabetes Mellitus Type II and Intervertebral Disc Degeneration in Diabetic Rodent Models : A Systematic and Comprehensive Review . - pubmed
The number of diabetic patients grows constantly worldwide . - pubmed
T2DM rodent models provide versatile tools to study this interrelation . - pubmed
, experimental study with clearly outlined methods investigating IVDD in diabetic rodent models ) and exclusion ( e.g. - pubmed
, non - experimental ) criteria , we included 23 studies from 1992 to 2020 analyzing different aspects of IVDD in diabetic rodents , such as on pathogenesis ( e.g. - pubmed
One strong , 18 moderate , and three mild evidences of the link between DM and IVDD in rodents were found , while only one study has not approved this link . - pubmed
Further studies are required to confirm these results in dyspnoeic dogs . - pubmed
Since 2010 , porcine epidemic diarrhea virus ( PEDV ) has received global attention with the emergence of variant strains characterized with high pathogenicity . - pubmed
Relationship between regional myocardial procainamide concentration and regional myocardial blood flow during ischemia in the dog . - pubmed
The results of conservative therapy in 160 patients with so - called idiopathic facial paralysis are reported . - pubmed
In incomplete paralysis the number of patients restored to health was about 96.1 % , and 93.3 % incomplete paralysis . - pubmed
Inhibitory effect of sarcophytol A on development of spontaneous hepatomas in mice . - pubmed
The inhibitory effect of sarcophytol A , a cembrane - type diterpene isolated from a marine soft coral , Sarcophyton glaucum , on development of spontaneous hepatomas was investigated in C3H / HeNCrj mice . - pubmed
At week 65 of the experiment , mice were examined for hepatomas . - pubmed
The percentages of hepatoma - bearing mice of the subgroup with three or more tumors and the tumor diameters of the group treated with sarcophytol A were smaller than those of the control group . - pubmed
These results suggest that sarcophytol A inhibits the development of spontaneous hepatomas without toxicity , and should be considered as a possible cancer chemopreventive agent for hepatomas in humans . - pubmed
Three out of 4 hybrids tested were able to form colonies in soft agar and to grow as tumors in either nude or ( BALB / c x C3H ) F1 mice , albeit at a reduced rate . - pubmed
Between 40 and 43 Haemophilus influenzae isolates obtained from Greece , Lebanon , Israel and Morocco respectively ( a total of 167 strains ) were analysed for prevalence of resistance to six different drugs . - pubmed
A comprehensive clinicoimmunological examination was made of 105 male patients aged 35 - 65 years who suffered from coronary heart disease . - pubmed
Immunomodulating therapy is regarded as an additional approach to the treatment of CHD patients with marked lipoprotein sensitization . - pubmed
Twelve healthy male volunteers participated in four experimental occasions during each of which they were dosed with one of the following anti - psychotic drugs : chlorpromazine ( 50 mg ) , haloperidol ( 3 mg ) , sulpiride ( 400 mg ) and placebo . - pubmed
Eighteen MS patients with visual acuity of 20/30 or better and without recent visual complaints , and 14 age- and sex - matched controls were studied by TV pupillography . - pubmed
It is concluded that MS patients with preserved visual acuity have only discrete autonomic pupillary disturbances and that the PLR delay is related to disease progression . - pubmed
Histomorphometry was performed on representative trephine biopsies of the bone marrow on admission of 50 patients ( 21 male , 29 female - age 67 years ) with so - called primary osteomyelofibrosis /- sclerosis ( OMF ) not preceded by any other subtype of chronic myeloproliferative disorders . - pubmed
Secondly , we concentrated on a discrimination of OMF patients into two subgroups according to bone marrow morphology and clinical variables . - pubmed
We describe a patient with carcinoma of a fallopian tube initially presenting with oliguric renal failure . - pubmed
In this study , large numbers of hybridomas ( produced by syngeneic immunization with B16 mouse melanoma and fusion with NS-1 myeloma cells ) were screened for the production of antibodies that affected morphology and growth of animal and human tumor cells in vitro . - pubmed
In vivo both antibodies reduced the number of growing lung tumors of B16 melanoma in C57BL / 6 mice by 70%-90 % when injected 3 days after the tumor cells . - pubmed
[ Development of anemia in newborn animals after acute hypoxia ] . - pubmed
[ Cytological assessment of the action of Mentadent C toothpaste on the gingival epithelium in patients with periodontal diseases ] . - pubmed
[ Results of using autologous and demineralized allogeneic bone transplants in reconstructive operations on the mandible in children with the syndrome of the first and second branchial arches ] . - pubmed
A comparative clinico - roentgenological assessment of results of transplantation of auto- and allogenic demineralized transplants in reconstructive operations on the mandible was made in 58 children with the syndrome of the first and second branchial arches aged from 1 to 14 years . - pubmed
Because of autodigestion of lactose by its endogenous bacteria , the lactose in yogurt is better absorbed than other sources of lactose in lactase - deficient subjects . - pubmed
Between 1981 and 1985 , 27 patients with aplastic anemia have been treated by immunosuppression with antilymphocyte globulin and prednisolone or allogeneic bone marrow transplantation . - pubmed
Long - term follow - up of dermatitis herpetiformis in children . - pubmed
Treatment with a gluten - free diet alone led to a reversal of the intestinal abnormality in 100 % of our children and to the disappearance of cutaneous lesions in 82 % of reported cases . - pubmed
[ Assay of leucocyte adherence inhibition in patients with ovarian cancer ] . - pubmed
Is hyperventilation a physiologically significant stimulus for prostaglandin release in the human pulmonary vascular bed ? - pubmed
The influence of hyperventilation on the pulmonary prostaglandin ( PG ) release was studied in healthy volunteers . - pubmed
The increased ventilation did not alter the arterio - venous PG concentration differences suggesting that hyperventilation accompanying the activation of chemoreceptors is not a physiologically significant stimulus for the pulmonary PG release in man . - pubmed
The majority of infections were caused by Pseudomonas , Enterobacter , Klebsiella , and Escherichia coli . - pubmed
Overall , aztreonam was superior to tobramycin for treatment of pneumonia due to susceptible gram - negative bacteria in these critical care patients . - pubmed
[ Nephron function in acute glycerol - induced renal insufficiency in rabbits ] . - pubmed
Venous and nerve invasion as prognostic factors in postoperative survival of patients with resectable cancer of the rectum . - pubmed
The histopathologic and clinical findings in 682 patients with carcinoma of the rectum have been analyzed . - pubmed
The five - year survival rate for patients with resectable tumors was 49 per cent . - pubmed
When venous invasion was observed , liver metastases developed over three times as frequently in these patients as when metastases were not demonstrated . - pubmed
Diminished renal function in the geriatric group may explain the slower elimination of the drug in the old subjects . - pubmed
Both groups were inferior to 10 controls , and frontal - lesioned patients were inferior to those with posterior lesions . - pubmed
OBJECTIVES : To examine the effects of drug treatment on laboratory exercise tests in relation to measures of daily activity in patients with chronic heart failure . - pubmed
The pedometer scores of the patients with heart failure were greatly reduced compared with those of the controls ( 258 ( 45 ) x 10(2 ) v 619 ( 67 ) x 10(2 ) steps / week , P & lt ; 0.001 ) and after 12 weeks of treatment were unchanged ( 261 ( 42 ) x 10(2 ) steps / week ) . - pubmed
CONCLUSIONS : These data confirm the need to use different exercise protocols when assessing the benefits of drug treatment in patients with chronic heart failure . - pubmed
BACKGROUND : Reports have implied etoposide as the cause of secondary leukaemia in patients treated for germ cell cancer . - pubmed
PATIENTS AND METHODS : Between 1979 and 1992 , 679 male patients with germ cell cancer received etoposide containing chemotherapy . - pubmed
RESULTS : Six of 679 patients developed acute myeloid leukaemia ( relative risk 150 ; CI : 55 - 326 ) . - pubmed
None of these patients had a primary mediastinal germ cell tumour and only 1 patient received previous radiotherapy . - pubmed
CONCLUSION : The benefit of etoposide containing protocols outweigh the risk of leukaemia in patients with intermediate or high risk disease , however in patients with good risk disease non - etoposide containing protocols should be explored . - pubmed
These data indicate that there is a specific risk to naming after dominant ATL for adult temporal lobe epilepsy ( TLE ) patients with a left hemisphere focus and the absence of an early risk factor for the development of seizures . - pubmed
A 35 - year - old male presented with trigeminal neuralgia associated with venous angioma at the root entry zone . - pubmed
The possibility of a venous anomaly should be considered in younger patients with trigeminal neuralgia . - pubmed
We report the establishment of a human fetal osteoblast cell line derived from biopsies obtained from a spontaneous miscarriage . - pubmed
Results of this study provide further information concerning clinical use of MMI in dogs and may contribute to better understanding of the mechanism of MMI protection against chemically induced nephrotoxicosis . - pubmed
Human individuals were hypothesized to use the same pattern of jaw muscle activity to produce the same bite force . - pubmed
Effect of ketoprofen on Escherichia coli heat - stable enterotoxin - induced diarrhea of calves . - pubmed
To evaluate the effect of ketoprofen on fecal output during secretory diarrhea , 16 calves were given approximately 200 micrograms of heat - stable Escherichia coli enterotoxin by suckling on 2 occasions . - pubmed
[ Methods for the curative treatment of pleural empyema with bronchial fistulae in patients with pulmonary tuberculosis ] . - pubmed
In contrast to non - specific pleural empyemas in which closed sanitization is sufficiently beneficial , an early application of thoracostoma is essential for patients with tuberculous pleural empyema with bronchial fistulas . - pubmed
This has been supported by the comparative analysis of the outcomes of radical operations in 139 patients following closed and open management of the empyemic cavity in pulmonary tuberculosis . - pubmed
Convulsions induced by methyl beta - carboline-3 - carboxylate in mice : effects of preceding saline injections . - pubmed
or of saline were studied in nine inbred mouse strains . - pubmed
Detection of occult lymphoma in the peripheral blood and bone marrow of patients with untreated early - stage and advanced - stage follicular lymphoma . - pubmed
PATIENTS AND METHODS : Bone marrow and peripheral - blood samples from 28 newly diagnosed patients with follicular lymphoma referred from several different medical centers were assessed . - pubmed
RESULTS : Morphologic assessment of the bone marrow was positive for lymphoma cells in 11 of 28 patients . - pubmed
PCR amplification of t(14;18 ) breakpoint DNA detected lymphoma cells in 17 of 24 patients assessed . - pubmed
Lymphoma cells were found in the bone marrow and/or peripheral blood as frequently in early - stage patients as in advanced - stage patients . - pubmed
CONCLUSION : PCR amplification of t(14;18 ) breakpoint DNA together with morphologic assessment had the highest yield of detecting lymphoma cells in the bone marrow and/or peripheral blood of our population of newly diagnosed patients with follicular lymphoma . - pubmed
Twenty - two patients with cerebral vascular accident ( CVA ) , clinically confirmed by head computed tomography , were observed for symptoms of the reflex sympathetic dystrophy syndrome ( RSDS ) . - pubmed
All patients received triple phase bone scans ; 16 scans were positive for RSDS . - pubmed
Patients with negative scans had no symptoms of RSDS . - pubmed
Five patients with positive scans had RSDS symptoms at the time of bone scanning . - pubmed
Seven of 11 patients with positive scans but no symptoms of RSDS at the time of bone scan developed symptoms of RSDS within six months . - pubmed
Considering only those patients who were asymptomatic for RSDS at the time of bone scanning , we found bone scanning to be a good predictor for the future development of clinical RSDS . - pubmed
We found the correlation between positive bone scans and the subsequent development of clinical RSDS in previously asymptomatic individuals to be statistically significant ( p & lt ; 0.05 ) . - pubmed
We conclude that bone scans may be a good predictor of patients at risk for developing clinical RSDS after CVA . - pubmed
OBJECTIVE : To examine the use of oral ciprofloxacin and parenteral antimicrobials in the treatment of acute infection ( respiratory tract , urinary tract , blood ) in hospitalized patients , with particular reference to severity of infection , outcome , and associated economic implications of each treatment . - pubmed
RESULTS : Four hundred eighty - five patients were enrolled for analysis ; 208 of the patients had respiratory tract infection , 112 had urinary tract infection , 138 had septicemia , and 27 had mixed infections . - pubmed
Sepsis scores were applied to 152 patients receiving oral ciprofloxacin and 333 patients receiving parenteral antimicrobials and yielded mean scores of 5.9 ( SD 3.1 , range 1 - 13 ) and 8.7 ( SD 4.2 , range 1 - 22 ) , respectively . - pubmed
Of 485 patients , 188 were paired according to sepsis score results and route of administration . - pubmed
Mouse infections with the pinworm , Syphacia obvelata , were evaluated as a potential model of human enterobiasis . - pubmed
To find out whether a long - term physical illness since childhood increases the risk of experiencing psychological and somatic symptoms , we interviewed a group of 487 patients aged 20 - 25 years and compared these findings to 211 controls . - pubmed
A prospective study of quantification of urinary incontinence and quality of life in patients undergoing radical retropubic prostatectomy . - pubmed
OBJECTIVES : To prospectively evaluate the level of urinary incontinence and its impact on quality of life in patients undergoing radical retropubic prostatectomy . - pubmed
METHODS : Patients completed a 24 - hour pad test together with an incontinence and quality - of - life questionnaire before and after surgery . - pubmed
The 24 - hour pad test demonstrated that 87 % of patients had some incontinence at 1 month and 63 % at 6 months after surgery . - pubmed
Seventy - five patients with malignant tumors of the upper jaw and nasal cavity have received combination therapy . - pubmed
METHODS : To determine whether a 100 mg alternate day dose of aspirin given in regular and enteric coated formulations for a 2 - week period is sufficient to inhibit platelet function in men and women , a randomized , double - blind , placebo - controlled trial was conducted among 22 healthy volunteers evaluating the effects of these preparations on platelet aggregation induced by arachidonic acid , adenosine diphosphate , and epinephrine , and on plasma concentrations of thromboxane and prostacyclin . - pubmed
The clinical efficacy of this dose and formulation of aspirin is being tested in the ongoing Women 's Health Study , a randomized , double - blind , placebo - controlled trial of 40000 female health professionals designed in part to assess the benefits and risks of 100 mg alternate day aspirin in the primary prevention of cardiovascular disease . - pubmed
Cell surface carbohydrates as prognostic markers in human carcinomas . - pubmed
Tumour - associated carbohydrate changes have been used in the diagnosis of human cancers . - pubmed
STUDY DESIGN : A retrospective study of 1263 patients with symptomatic yeast vaginitis confirmed by culture techniques was performed . - pubmed
MATERIALS AND METHODS : Between June 1995 and January 1996 , 2 patients with a solitary metachronous contralateral adrenal metastasis from renal cell cancer were evaluated . - pubmed
Both patients had undergone radical nephrectomy for localized renal cancer 5 years previously . - pubmed
Neither patient had recurrent cancer at 11 and 16 months of followup . - pubmed
CONCLUSIONS : Laparoscopic adrenalectomy for metastatic renal cell cancer was performed successfully in 2 patients . - pubmed
However , the short - term benefits to the patient of earlier ambulation , decreased pain , minimal incisions and shortened convalescence must be weighted against the as yet unknown long - term ( 5 years ) results . - pubmed
High - speed rotational atherectomy of human coronary stenoses : acute and one - year outcomes from the New Approaches to Coronary Intervention ( NACI ) registry . - pubmed
A total of 525 patients with 670 lesions treated with RA form the substrate of this report . - pubmed
MI occurred in 6 % of patients , consisting predominantly of non - Q - wave MI ( 5 % ) . - pubmed
At 1 - year follow - up , 27 % of patients required target lesion revascularization and 30 % had experienced death , Q - wave MI , or target lesion revascularization . - pubmed
Beta - carotene concentration in buccal mucosal cells with and without dysplastic oral leukoplakia after long - term beta - carotene supplementation in male smokers . - pubmed
Altogether 17 subjects showed oral leukoplakia , 7 had dysplasia . - pubmed
In these 7 subjects , the BC concentration in buccal mucosal cells did not differ statistically significantly compared to subjects with only hyperkeratosis ( n = 10 ) ( F - test , P = 0.74 ) . - pubmed
There was no evidence to support an association between cellular BC concentration and precancerous lesions among the few subjects having them in their oral mucosae . - pubmed
No difference was found in terms of intraoperative complications , proportion of patients who required transfusion , endometritis , sepsis , febrile morbidity , and urinary tract infections . - pubmed
The second was a prospective study of 39 patients ( 19F , 20 M ) followed for a median of 30 months ( range 5 - 64 months ) following either allogeneic ( allo , n = 29 ) or autologous ( auto , n = 10 ) BMT to determine if bone loss was related to treatment of graft versus host disease ( GVHD ) with glucocorticoids and cyclosporine A , high bone turnover rates , or hypogonadism . - pubmed
Urinary bone resorption markers were higher than in normal gender- and age - matched control subjects . - pubmed
Glucocorticoid - pretreated women with amenorrhoea had lower lumbar spine ( LS ) and FN BMDs than eumenorrheic women and women receiving HRT . - pubmed
Avascular necrosis of the femoral head occurred in four , and vertebral and rib fractures occurred in one of the allo BMT patients , but in no auto BMT patients . - pubmed
In conclusion , BMT recipients are at risk of osteoporosis secondary to bone loss associated with their underlying illness and/or chemotherapy , particularly in female autograft recipients , and in allograft recipients secondary to GVHD and its treatment . - pubmed
Efficacy and safety of self - start therapy in women with recurrent urinary tract infections . - pubmed
PURPOSE : We evaluated the efficacy of self - start therapy in women with recurrent urinary tract infections . - pubmed
MATERIALS AND METHODS : Women with recurrent urinary tract infections received a dip slide urine culture kit and 6 tablets of norfloxacin ( 400 mg . ) - pubmed
At each symptomatic urinary tract infection episode the patient performed a culture and initiated therapy . - pubmed
Six women followed for 74 months were asymptomatic and 9 followed for 103 months had no infections . - pubmed
A total of 28 women followed for 355 months had 84 symptomatic episodes and 25 had 67 urinary tract infections . - pubmed
Patients had symptomatic episodes at a rate of 2.8 per patient - year ( range 0 to 9 ) and infections at a rate of 2.3 per patient - year ( range 0 to 9 ) . - pubmed
A 63 - year - old female was transferred to our hospital suffering from gait disturbance and dysarthria . - pubmed
An economic analysis of an aggressive diagnostic strategy with single photon emission computed tomography myocardial perfusion imaging and early exercise stress testing in emergency department patients who present with chest pain but nondiagnostic electrocardiograms : results from a randomized trial . - pubmed
RESULTS : We enrolled 46 patients , 9 with acute myocardial infarctions . - pubmed
CONCLUSION : An ED chest pain diagnostic strategy incorporating acute resting ( 99m ) Tc tetrofosmin SPECT imaging and early exercise stress testing may lead to reduced in - hospital costs and decreased length of stay for patients with acute chest pain and nondiagnostic ECGs . - pubmed
SUBJECTS : 108 patients with single uncomplicated hydatid cysts who were operated on in two clinics between 1990 and 1995 . - pubmed
CONCLUSION : Introflexion and omentoplasty after partial cystectomy for a single uncomplicated hydatid cyst caused significantly fewer complications than external drainage , and patients left hospital sooner . - pubmed
BACKGROUND : Multivitamin supplementation in pregnant women may reduce the risks of cardiovascular defects , oral clefts , and urinary tract defects in their infants . - pubmed
The use of Hirudo medicinalis in nipple - areolar congestion . - pubmed
However , its place in the management of anticipatory and delayed vomiting in cancer treatment and as a rescue antiemetic in surgical patients needs to be further explored . - pubmed
Furthermore , recent animal and human research also reflects its possible novel application in the treatment of other disease states , such as alcoholism , cocaine addiction , opioid withdrawal syndrome , anxiety disorders , gastrointestinal motility disorders , Tourette ' s syndrome and pruritus . - pubmed
Electrical foot - shock stress induced both DOPA and dopamine release , measured by microdialysis , from the nucleus accumbens in freely moving rats . - pubmed
PURPOSE : The aim of this study was to assess the value of endoanal ultrasound ( EUS ) in comparison to anal manometry and operative findings in patients suffering from faecal incontinence . - pubmed
Patient history , localisation of sphincter defects and therapeutic modalities were analysed . - pubmed
METHODS : Over a 3 - years period , 92 patients with faecal incontinence were investigated by endoanal ultrasound . - pubmed
CONCLUSION : Endoanal ultrasound is a very sensitive method for localizing anal sphincter defects and is mandatory in the assessment of patients with faecal incontinence . - pubmed
Differences in risk factors among clinical types of oral candidiasis in the Women 's Interagency HIV Study . - pubmed
STUDY DESIGN : A cross - sectional analysis of baseline data for 577 human immunodeficiency virus ( HIV )- seropositive and 152 HIV - seronegative women from the Women 's Interagency HIV Study was conducted . - pubmed
HIV seropositivity was associated with PC , EC , and DS , but not AC . - pubmed
Analysis of the cytotoxicity and mutagenicity of drinking water disinfection by - products in Salmonella typhimurium . - pubmed
We analyzed the cytotoxicity and mutagenicity of the drinking water disinfection by - products ( DBPs ) bromoform ( BF ) , bromoacetic acid ( BA ) , dibromoacetic acid ( DBA ) , tribromoacetic acid ( TCA ) , chloroform ( CF ) , chloroacetic acid ( CA ) , dichloroacetic acid ( DCA ) , trichloroacetic acid ( TCA ) , 3 - chloro-4 -( dichloromethyl )- 5 - hydroxy-2 [ 5H ]- furanone ( MX ) , and potassium bromate ( KBrO3 ) in Salmonella typhimurium strains TA98 , TA100 , and RSJ100 + /- S9 . - pubmed
TA100 - S9 was the most sensitive strain for these DBPs . - pubmed
METHODS : Subjects were 24 premenopausal women ( mean age , 39.5+/-9.4 years ; range , 32 - 52 years ) with uterine leiomyomas . - pubmed
For the radio - carpal arthrosis , injuries are often present for elderly woman ( P & lt ; 0.01 ) and young man ( P & lt ; 0.05 ) . - pubmed
Epstein - Barr virus ( EBV ) is the major triggering factor producing hemophagocytic syndrome or hemophagocytic lymphohistiocytosis ( HLH ) . - pubmed
In patients with EBV - HLH , the EBV - infected T cells or natural killer ( NK ) cells are mostly mono- or oligo - clonally proliferating , where hypercytokinemia plays a major role and causes hemophagocytosis , cellular damage and dysfunction of various organs . - pubmed
Arachidonic acid ( AA)-induced cytotoxicity was evaluated in leukocytes : the human leukemia cell lines HL-60 , Jurkat and Raji and in rat lymphocytes . - pubmed
The recognition and invasion of human erythrocytes by the most lethal malaria parasite Plasmodium falciparum is dependent on multiple ligand - receptor interactions . - pubmed
One patient developed a necrotizing fasciltis , and in two others , migration of the tube was observed . - pubmed
A - THIB " was defined as the absolute difference in integrated backscatter between the left ( subendocardial ) and right ( subepicardial ) ventricular halves of the myocardium in the septum and posterior wall , and was measured in 11 patients with PSS and 10 age- and sex - matched healthy participants . - pubmed
A - THIB in patients with PSS was higher than that in healthy participants ( 1.3 + /- 1.3 vs 4.0 + /- 1.4 dB for the septum and 1.1 + /- 0.7 dB vs 2.8 + /- 0.4 dB for the posterior wall ; mean + /- SD , respectively , P & lt;.0005 ) . - pubmed
The patient was a 57 - year - old Japanese man who had moderate splenomegaly , and who had undergone splenectomy for improvement of severe autoimmune hemolytic anemia and to rule out malignancy in the spleen . - pubmed
Monoclonal antibodies ( MoAbs ) are increasingly used in the treatment of patients with hematological malignancies and autoimmune diseases . - pubmed
Tourniquet shock in rats ; reversibility in the terminal phase . - pubmed
Some cultural characteristics of Staphylococcus aureus strains from superficial skin infections . - pubmed
Phosphate clearance and tubular reabsorption of phosphate in patients with parathyroid disorders and renal failure . - pubmed
Including patients with diabetes mellitus or coronary artery bypass grafting decreases the association between heart rate variability and mortality after myocardial infarction . - pubmed
BACKGROUND : Decreased heart rate variability ( HRV ) is often assumed to be associated with mortality in all patients after myocardial infarction ( MI ) , independent of clinical factors or time after MI . - pubmed
Patients were 71 + /- 120 days after MI . - pubmed
A total of 735 pre - therapy tapes were analyzed in patients who had ventricular premature contractions ( VPCs ) suppressed on the first treatment . - pubmed
The association of clinical and demographic factors and 24 - hour , daytime , and nighttime HRV to mortality in all patients , patients without coronary artery bypass graft ( CABG ) surgery between the qualifying MI and the Holter monitoring , and patients with neither CABG nor diabetes mellitus was determined with univariate Cox regression analysis . - pubmed
Sleep problems such as nocturnal awakening and abnormality in the percentage of rapid eye movement ( REM ) sleep are frequently observed in patients with SMS , and several medications have been administered to improve the sleep disorders . - pubmed
Two dogs were found to have clinical , histopathological and immunofluorescent findings compatible with a diagnosis of canine discoid lupus erythematosus . - pubmed
The effect of acetylshikonin isolated from Lithospermum canescens roots on tumor - induced cutaneous angiogenesis . - pubmed
roots , in a daily dose of 200 microg for 3 days , inhibited cutaneous angiogenesis induced by L-1 sarcoma cells in Balb / c mice . - pubmed
[ Awareness of disease in dementia : preliminary results in patients with mild and moderate Alzheimer ' s disease ] . - pubmed
RESULTS : Awareness of disease and its consequences were present in 66.7 % patients with mild AD ( n=18 ) . - pubmed
A 61 - year - old woman presented with a huge hemangioma on the right ventricle . - pubmed
Four patients experienced painful paresthesias and 3 patients had accidental punctures of axillary vessels . - pubmed
Assessing the clinical significance of drug interactions with fluorouracil in patients with colorectal cancer . - pubmed
Phenotypic viral susceptibility to SPD754 and five other NRTIs was tested using the PhenoSense HIV assay and expressed as median fold - change compared with a reference strain . - pubmed
In part 1 ( 6 weeks ) , 102 patients ( & gt ; or = 12 years old ) with hemophilic arthropathy were randomized to receive 90 mg etoricoxib once daily or placebo ( 1:1 ratio ) . - pubmed
Efficacy end points included Patient Assessment of Arthropathy Pain , Patient Global Assessment of Arthropathy Disease Status , and Investigator Global Assessment of Arthropathy Disease Status . - pubmed
There was no significant difference between the blood donors and the patients with hepatitis B as regards virological markers , including viral load , when the HBV genotype was taken into account . - pubmed
Possible involvement of oxidative stress in dicyclanil - induced hepatocarcinogenesis in mice . - pubmed
THE MEASUREMENT AND METABOLISM OF THIAMIN AND OF A PYRIMIDINE STIMULATING YEAST FERMENTATION FOUND IN THE BLOOD CELLS AND URINE OF PATIENTS WITH LEUKEMIA . - pubmed
We present six patients , each of whom had extensive fractures of the floor of the orbit that extended posteriorly to its anatomical limit . - pubmed
Abnormalities in the susceptibility of certain cells to receptor - induced death are known to lead to certain human diseases ( e.g. - pubmed
AIM : To analyze various oxidative stress parameters in the saliva and serum of patients with chronic renal failure ( CRF ) and/or diabetes mellitus ( DM ) , and to compare them in dialytic vs. pre - dialytic patients . - pubmed
METHOD : 50 consenting patients were divided into five subgroups of patients : severe CRF ( dialytic ) without DM , severe CRF ( dialytic ) with DM , mild CRF ( pre - dialytic ) without DM , mild CRF ( pre - dialytic ) with DM , and with DM but without CRF ( controls ) . - pubmed
Relative role of left ventricular geometric remodeling and of morphological and functional myocardial remodeling in the transition from compensated hypertrophy to heart failure in rats with supravalvar aortic stenosis . - pubmed
OBJECTIVE : To evaluate the relative contribution of left ventricular ( LV ) geometric remodeling and of morphological and functional myocardial changes in rats with induced supravalvar aortic stenosis ( SAS ) , in the transition from compensated hypertrophy to congestive heart failure ( CHF ) . - pubmed
INTRODUCTION AND OBJECTIVES : In the second part of an analysis of a 10 - year period of treating oral cancer patients , the focus was the efficiency of treatment , recurrence rates and survival . - pubmed
PATIENTS AND METHODS : From 1485 patients with oral and maxillofacial malignant tumours , 1072 cases could be evaluated . - pubmed
RESULTS : From all patients studied , 811 underwent surgical treatment alone , the mean recurrence rate was 23 % . - pubmed
We reviewed the incidence and the impact of posttransplant lymphoproliferative disorders ( PTLDs ) on patient survival among a consecutive series of 255 patients . - pubmed
Olfactory dysfunction is a prominent symptom in Parkinson ' s disease ( PD ) and found in about 70 - 100 % of patients . - pubmed
We suggest that the increase of dopaminergic cells in the olfactory bulb is responsible for the hyposmia in PD patients . - pubmed
Are animals autistic savants . - pubmed
Apoptosis of human pancreatic cancer cells induced by Triptolide . - pubmed
METHODS : Human pancreatic cancer cell line SW1990 was cultured in DMEM media for this study . - pubmed
Flow cytometry and TUNEL assay were used to detect the apoptosis of human pancreatic cancer cells before and after TL treatment . - pubmed
RESULTS : TL inhibited the growth of human pancreatic cancer cells in a dose - and time - dependent manner . - pubmed
TL induced human pancreatic cancer cells to undergo apoptosis with typically apoptotic characteristics . - pubmed
TUNEL assay showed that after the treatment of human pancreatic cancer cells with 40 ng / mL TL for 12 h and 24 h , the apoptotic rates of human pancreatic cancer cells increased significantly . - pubmed
CONCLUSION : TL is able to induce the apoptosis in human pancreatic cancer cells . - pubmed
( Jarilla ) plants exhibited a pronounced cytotoxic effect by arresting cell viability at a level of 35 % against the MCF-7 cell line , a human breast adenocarcinoma , while only a weak cytotoxic effect was observed for the aqueous extract . - pubmed
Previous reports have stated that such optic disc hemorrhages are associated with intrapapillary bleeding largely in patients of Asian origin who are visually symptomatic from this process . - pubmed
We have encountered patients with PSH who have clinical features that differ from those described in these reports . - pubmed
Medical records of 10 patients with isolated peripapillary subretinal hemorrhages were reviewed for clinical characteristics and ancillary testing , including demographics , history , complete eye examination , visual fields , fundus photos , ultrasound , and fluorescein angiography ( four patients ) at presentation and follow - up . - pubmed
We excluded patients with drusen , neovascular membranes , disc edema , and intrapapillary hemorrhages . - pubmed
RESULTS : There were 10 patients , all white women without visual symptoms , who had isolated , monocular , nasal , or superonasal peripapillary subretinal hemorrhage , a dysplastic crowded - tilted optic disc , myopia , and normal visual function . - pubmed
CONCLUSIONS : We have described a benign syndrome of isolated PSH in crowded and tilted optic discs in myopic eyes of white women . - pubmed
METHOD / RESULTS : A 62 - year - old female patient presents to the emergency department with complaints of a bleeding vaginal mass , pain referred to the vaginal introitus and dysu - ria . - pubmed
Nonetheless , given the balance of data both in cell , animal and human studies , the use of phosphate lowering strategies at earlier stages of CKD , perhaps even prior to serum phosphate level rising , may well be justified . - pubmed
Spontaneous pyopneumothorax is a very rare occurrence , even in cancer treated patients . - pubmed
We report the case of a 64 year old woman who presented with symptomatology of gallstone disease but was radiologically shown to have a polyp within the gallbladder . - pubmed
We conclude that the development of cortical GABAergic neurons have exclusive features in primates that need to be considered in order to understand pathological mechanisms leading to some neurological and psychiatric diseases . - pubmed
Although it is a rare syndrome , early diagnosis and treatment prevents permanent neurological deficits and improve patient 's quality of life . - pubmed
The goal of management of dysarthria in ALS patients is to optimize communication effectiveness for as long as possible . - pubmed
This review summarizes the current state of knowledge on the clinical features , differential diagnosis , pathophysiology , investigations and management of dysarthria in ALS patients . - pubmed
Methylmercury ( Me - Hg ) poisoning ( Minamata disease : MD ) is one of the most severe types of disease caused by humans to humans in Japan . - pubmed
INTRODUCTION : Erythrodermic psoriasis is a rare generalized clinical presentation of psoriasis in children and adults . - pubmed
CASE PRESENTATION : We present the case of a 9 - year - old native Hispanic girl with severe erythrodermic psoriasis associated with uncommon advanced nail and joint manifestations . - pubmed
Increased efficacy of early spinal cord stimulation in an animal model of neuropathic pain . - pubmed
Although spinal cord stimulation ( SCS ) is an established treatment for chronic neuropathic pain , pain relief is still not successful in a large group of patients . - pubmed
Animals with tactile allodynia received 30min of SCS . - pubmed
Out of the 13 allodynic animals that received early SCS , 10 ( 77 % ) responded to SCS with significantly increased withdrawal thresholds , compared to 38 % in the late SCS group . - pubmed
Early SCS treatment of neuropathic rats is more effective as compared to the late SCS treatment . - pubmed
RESULTS : Fourteen patients ( 53.9 % ) had ear - lobe keloids and 11 ( 42.3 % ) of the patients developed the keloid from ear - piercing . - pubmed
On d78 , but not d135 , placental and fetal weights were reduced ( P & lt ; 0.05 ) in NR vs. C ewes . - pubmed
Some epidemiological surveys have shown an increased incidence of malignancies in patients with multiple Sclerosis ( MS ) . - pubmed
The organic extract of Periplaneta americana L. ( Dictyoptera ; Blattidae ) has been traditionally used in southwestern China as an alternative medicine against disorders such as hepatitis , trauma , gastric ulcers , burns , and heart disease . - pubmed
The most effective cytotoxic fraction was determined by way of repeated in vitro screenings against 12 distinct cultured human carcinoma cell lines : Eca 109 , BGC823 , HO8910 , LS174 T , CNE , HeLa , K562 , PC-3 , A549 , BEL 7404 , HL-60 , and KB , followed by in vivo antitumor assays of the lead fraction ( PAE60 ) . - pubmed
PAE60 reduced tumor growth in S180 - bearing immunocompetent mice by 72.62 % after 10 days following oral doses of 500 mg kg d-(1 ) compared with 78.75 % inhibition following 40 mg kg d-(1 ) of cyclophosphamide ( CTX ) . - pubmed
The contribution of gliosis to diffusion tensor anisotropy and tractography following traumatic brain injury : validation in the rat using Fourier analysis of stained tissue sections . - pubmed
It is hoped that this increased sensitivity will aid in the detection and prognostication in patients with traumatic injury . - pubmed
We developed a method to quantify the anisotropy of stained histological sections using Fourier analysis , and applied the method to a rat controlled cortical impact model to identify the specific pathological features that give rise to the diffusion tensor imaging changes in subacute to chronic traumatic brain injury . - pubmed
MATERIALS AND METHODS : We carried out a prospective observational study to determine the treatment response rate , tolerability and outcome of patients with cryptococcal meningitis in HIV treated with amphotericin B. - pubmed
RESULTS : A total of 27 patients were diagnosed with cryptococcal meningitis during the study period . - pubmed
Headache ( 96.29 % ) was the single most common presenting symptom of cryptococcal meningitis in HIV - infected patients , followed by vomiting ( 77.77 % ) and fever ( 66.66 % ) . - pubmed
CONCLUSIONS : We found that the recommended 2 weeks induction treatment with Amphotericin B monotherapy for HIV patients with cryptococcal meningitis in resource - limited settings may be suboptimal for at least one - third of the patients . - pubmed
Penile necrosis due to priapism developed after circumcision in a patient with protein S deficiency . - pubmed
METHODS : l Nine - year - old boy referred from another hospital with the sequelae of the penile ischemia with discoloration of the penis after traditional circumcision . - pubmed
These animals subsequently progress to acute leukemias . - pubmed
Postconditioning by mild hypoxic exposures reduces rat brain injury caused by severe hypoxia . - pubmed
The present study has been performed to determine whether postconditioning by mild episodes of hypobaric hypoxia ( hypoxic postconditioning , HP ) can reduce post - hypoxic brain injury in rats . - pubmed
OBJECTIVES : Determination of lymphatic metastasis is of great importance for both treatment planning and patient prognosis . - pubmed
Anti - fibrotic effect of Aliskiren in rats with deoxycorticosterone induced myocardial fibrosis and its potential mechanism . - pubmed
BACKGROUND : Distal femoral physis fractures with displacement are rare injuries seen in adolescents related with high incidence of complication . - pubmed
CASE REPORT : The case of a 14 - year - old boy with Salter - Harris type II displaced fracture underwent surgery with open reduction has been described . - pubmed
CONCLUSIONS : Knowledge of classification , prognosis and methods of treatment is necessary in accurate pre- and postoperative assessment of physial fractures in adolescents . - pubmed
Management of adverse events of targeted therapies in normal and special patients with metastatic renal cell carcinoma . - pubmed
These biological agents have toxicity profiles that differ from those accompanying current chemotherapeutic agents , but their novelty leads to a lack of exhaustive clinical data regarding related adverse events ( AEs ) , whose symptoms may overlap with those of the chronic illnesses of patients with mRCC such as hypertension , hyperglycemia , and pneumonitis . - pubmed
Recommendations for treating these adverse events in patients with mRCC are usually the same as those for the general population . - pubmed
Some groups of patients with mRCC , such as frail , elderly patients , and patients with renal or liver dysfunction , require special management of AEs . - pubmed
RESULTS : A significant reduction in human biting rate was recorded after the third round of IRS , specifically in Adjohoun ( 89.78 % ) , Dangbo ( 56.8 % ) and Misserete ( 93.22 % ) where an inhabitant received less than 2 bites of An . - pubmed
Chlorpyrifos induced testicular damage in rats : ameliorative effect of glutathione antioxidant . - pubmed
CPF was administered orally , in a dose of 30 mg / kg body weight to male rats for 90 days , twice weekly . - pubmed
MATERIALS AND METHODS : Twenty - eight patients 11 months to 9 years of age presenting with chronic constipation , with contrast enema showing dilated rectum and sigmoid colon were included in the study . - pubmed
Ten patients had aganglionosis ( of which 5 had ganglion cells present in the proximal part of speciment ) , 7 had normal histology , 7 had hypoganglionosis , 2 had intestinal neuronal dysplasia , one had nerve hypertrophy and one had immature ganglia . - pubmed
CONCLUSION : Anorectal myectomy is an effective and technically simple procedure in selected patients with chronic refractory constipation , for both diagnostic and therapeutic purpose . - pubmed
Because apart from confirming Hirschsprung ' s disease , it also therapeutically relieves symptoms in 93 % of patients with chronic refractory constipation . - pubmed
EXPERIMENTAL APPROACH : We used MRC5 human lung fibroblasts and primary pulmonary fibroblasts of individuals with and without COPD . - pubmed
EXPERIMENTAL APPROACH : Right and left ventricular trabeculae from freshly explanted hearts of 5 non - beta - blocker - treated and 15 metoprolol - treated patients with terminal heart failure were paced to contract at 1 Hz . - pubmed
The overall survival of patients with gastric cancer has increased markedly in Korea , even higher than those of developed nations in Western world . - pubmed
OBJECTIVE : The main objective of this study was to evaluate antidepressant activity of vanillin in mice models of depression . - pubmed
Highly pathogenic avian influenza viruses ( HPAIVs ) cause lethal infection in chickens . - pubmed
Severe cases of HPAIV infections have been also reported in mammals , including humans . - pubmed
In the present study , the highly pathogenic avian influenza viruses A / turkey / Italy / 4580 / 1999 ( H7N1 ) ( Ty / Italy ) and A / chicken / Netherlands / 2586 / 2003 ( H7N7 ) ( Ck / NL ) and the low pathogenic avian influenza virus ( LPAIV ) A / chicken / Ibaraki / 1 / 2005 ( H5N2 ) ( Ck / Ibaraki ) were intranasally inoculated into chickens . - pubmed
The recent performance of the lead dengue vaccine in a phase 2b efficacy trial underscores dengue vaccine development challenges . - pubmed
METHODS : In - vitro studies using human coronary artery endothelial cells ( HCAEC ) and ex - vivo studies using white blood cells isolated from healthy and OSA subjects . - pubmed
During the past few years infections of poultry and humans with H7 subtypes have increased markedly . - pubmed
In humans , mild to fatal infections were caused by subtypes H7N2 , H7N3 , H7N7 and H7N9 . - pubmed
While infections of humans have been associated mostly with exposure to domestic poultry , infections of poultry have been linked to wild birds or live - bird markets . - pubmed
In contrast to recent cases caused by subtype H7N9 , human infections were usually self - limiting and rarely required antiviral medication . - pubmed
We identified patients who initiated antiplatelets within 14 days following discharge from hospitalizations for myocardial infarction ( MI ) or acute coronary syndrome . - pubmed
We matched patients using high - dimensional propensity scores ( hd - PSs ) and followed them for ischemic ( i.e. - pubmed
Phase 2 clinical trials for tuberculosis ( TB ) treatment require reliable culture methods to determine presence or absence of Mycobacterium tuberculosis ( Mtb ) over the course of therapy , as these trials are based primarily on bacteriological endpoints . - pubmed
We analyze 393 specimens from 50 HIV - negative Ugandan adults with newly - diagnosed , pulmonary TB and high acid - fast bacillus smear grade . - pubmed
MATERIALS AND METHODS : A prospective study of 200 consecutive newly detected highly active anti - retroviral therapy ( HAART ) naive HIV patients admitted over a one year period was conducted . - pubmed
Value of surgical decompression of compressed nerves in the lower extremity in patients with painful diabetic neuropathy : a randomized controlled trial . - pubmed
Forty - two patients with painful diabetic neuropathy were included . - pubmed
CONCLUSION : Surgical decompression of the nerves of the lower extremity can be added as a therapeutic option for patients with painful diabetic neuropathy who show signs of chronic nerve compression by means of a positive Tinel or other diagnostic criteria , when pain medication fails to reduce pain to an acceptable standard . - pubmed
Mouse infection studies confirmed a high - virulence capacity of these emm59 organisms . - pubmed
Inverse dynamic analyses were conducted in CHF patients and age- and exercise level - matched control subjects on an instrumented treadmill at self - selected treadmill walking speeds and at speeds representing +20 % and -20 % of the subjects ' preferred speed . - pubmed
CASE PRESENTATION : This case report describes a 58 - year - old Caucasian woman who is a cigarette smoker with a 10 - week history of fever of unknown origin , night sweats and weight loss of 12 kg . - pubmed
METHODS : Dissection of five temporal bones of Sus scrofa pigs obtained from UNIFESP - Surgical Skills Laboratory , removed with hole saw to avoid any injury and stored in formaldehyde 10 % for better conservation . - pubmed
Better knowledge of the molecular alterations could help in the management of patients with this type of precursor of invasive carcinoma . - pubmed
Cerebral aspergillosis in a diabetic patient leading to cerebral artery occlusion and ischemic stroke : a case report and literature review . - pubmed
Cerebral aspergillosis is a rare and highly fatal hematogenous infection most commonly found in immune compromised patients . - pubmed
PARTICIPANTS : Thirty - one eyes of 31 patients with FAF . - pubmed
INTERVENTION : All patients with FAF who had their first PK in Helsinki University Eye Hospital between January 1 , 1990 , and August 1 , 2011 , were identified and a retrospective analysis of the patient charts was performed . - pubmed
CONCLUSIONS : In a minority of FAF patients , PK improves vision . - pubmed
From a protocol biopsy population ( n = 690 ) , we randomly selected 100 LT patients in whom the biopsy was taken 7 - 10 days after LT . - pubmed
METHODS : 27 patients with AD and 16 with FTD were included . - pubmed
METHODS : A PRoBE design study enrolled 170 patients with lesions suspicious for OSCC . - pubmed
Molecular characterization of clinical isolates of Cyclospora cayetanensis from patients with diarrhea in India . - pubmed
PURPOSE : Cyclospora cayetanensis is an intestinal coccidian protozoan that has emerged as an important cause of both epidemic and endemic protracted diarrhea worldwide . - pubmed
Evaluation of outpatient discharge in patients with cutaneous melanoma . - pubmed
OBJECTIVE : to evaluate discharge in a group of patients with cutaneous melanoma according to recently established criteria . - pubmed
METHODS : we conducted an observational , cross - sectional study with 32 patients at the Hospital Universitario Clementino Fraga Filho ( HUCFF ) / Universidade Federal do Rio de Janeiro ( UFRJ ) , between 1995 and 2013 , in the following stages : IA ( 17 cases , 53.12 % ) , IB ( 4 cases , 12.5 % ) , IIA ( 3 cases , 9.37 % ) , IIC ( 1 case , 3.12 % ) , IIIB ( 1 case , 3.12 % ) , IIIC ( 3 cases , 9.37 % ) , melanomas in situ ( 2 cases , 6.25 % ) , Tx ( 1 case , 3.12 % ) . - pubmed
Paan chewing , tobacco and alcohol use are strong risk factors for this cancer in India . - pubmed
Human papillomaviruses ( HPVs ) are also related to a subset of head and neck cancers ( HNCs ) . - pubmed
We examined the association between oral HPV and oral cancer in a sample of Indian subjects participating in a hospital - based case - control study . - pubmed
Lack of a role for HPV infection in this study may reflect cultural or religious characteristics specific to this region in India that are not conducive to oral HPV transmission . - pubmed
These mutant mice also develop insulin resistance and are insensitive to the glucose - regulatory effects of estrogens . - pubmed
Therapy - related acute myeloid leukemia in patients with lymphoma : A report of four cases and review of the literature . - pubmed
At the time of diagnosis of t - AML , 3 of the 4 patients presented pancytopenia , whilst the remaining patient exhibited leukocytosis . - pubmed
The majority of the patients succumbed to their disease within 1 year of t - AML diagnosis , with the exception of the patient in case 3 , who survived following allogeneic hematopoietic stem cell transplantation ( allo - HSCT ) . - pubmed
Based on the present findings and a review of the literature , we propose that allo - HSCT should be recommended for patients at high risk of developing t - AML . - pubmed
Sympathetic Nervous System in Patients with Sleep Related Breathing Disorders . - pubmed
The objectives of this brief review are to summarize : 1 ) present knowledge concerning the mechanisms , magnitude and consequences of night- and day - time sympathetic nervous system activation in patients with these sleep - related breathing disorders ; and 2 ) the impact on the sympathetic nervous system and on blood pressure of their specific treatment . - pubmed
MATERIAL AND METHODS : We identified 131 patients with a histopathological diagnosis of astrocytic tumors ( diffuse astrocytoma , anaplastic astrocytoma and glioblastoma ) . - pubmed
Salicylate is a well - known ototoxic drug , and we induced tinnitus in rats using a model of long - term salicylate administration . - pubmed
The gap pre - pulse inhibition of acoustic startle test was used to infer tinnitus perception , and only rats in the chronic salicylate - treatment ( 14 days ) group showed evidence of experiencing tinnitus . - pubmed
Staphylococcus aureus Regulatory RNAs as Potential Biomarkers for Bloodstream Infections . - pubmed
BACKGROUND : Patients with frequent premature ventricular contractions ( PVCs ) are often highly symptomatic with significantly reduced quality - of - life . - pubmed
RESULTS : A total of 408 patients ( age 53.5 + - 15 years , 55 % female ) undergoing ablation for PVCs were included . - pubmed
32 % of patients showed a co - existing structural heart disease . - pubmed
In patients without structural heart disease , acute success was significantly higher compared with patients with structural heart disease ( 86 vs. 74 % , p = 0.002 ) . - pubmed
No patient suffered an acute myocardial infarction , stroke , or major bleeding . - pubmed
After 12 months ' follow - up , 99 % of patients were still alive showing a significant different mortality between patients with structural heart disease compared with those without ( 2.3 vs. 0 % , p = 0.012 ) . - pubmed
Neuropathic pain ( NPP ) is the main culprit among chronic pains affecting the normal life of patients . - pubmed
Then NPP rat model was induced by sciatic nerve chronic compression injury ( CCI ) and behavior tests were performed to analyze the pain behaviors upon mechanical , thermal and cold stimulations . - pubmed
Treatment of patients with aortic atherosclerotic disease with paclitaxel - associated lipid nanoparticles . - pubmed
In rabbits , atherosclerotic lesion size was reduced by 65 % following LDE - paclitaxel treatment . - pubmed
The current study aimed to test the effectiveness of LDE - paclitaxel on inpatients with aortic atherosclerosis . - pubmed
METHODS : This study tested a 175 mg / m2 body surface area dose of LDE - paclitaxel ( intravenous administration , 3/3 weeks for 6 cycles ) in patients with aortic atherosclerosis who were aged between 69 and 86 yrs . - pubmed
A control group of 9 untreated patients with aortic atherosclerosis ( 72 - 83 yrs ) was also observed . - pubmed
CONCLUSION : Treatment with LDE - paclitaxel was tolerated by patients with cardiovascular disease and showed the potential to reduce atherosclerotic lesion size . - pubmed
To conclude , we uncovered loss of chromosome 22 in almost half of all cases with hybrid neurofibromas / schwannomas of patients with multiple peripheral nerve sheath tumors . - pubmed
Here , we report for the first time , two patients of fatal liver injury due to anti - TB drugs in the presence of alpha-1 antitrypsin deficiency . - pubmed
Despite aggressive medical therapy and supportive care , patients developed multi - organ failure and died . - pubmed
A tumor model of nude mice with HCC was established for the study of tumor growth condition of tumor - bearing mice after the interference with lncRNA00673 expression . - pubmed
Safe and Effective Standards of Care : Supporting the Administration of T - VEC for Patients With Advanced Melanoma in the Outpatient Oncology Setting : . - pubmed
To date , 16 patients with locoregionally advanced melanoma have been treated with T - VEC . - pubmed
Currently , hepatocellular carcinoma ( HCC ) patients still have poor survival outcomes mainly due to the powerful mobility of HCC cells . - pubmed
In addition , 5 - year overall survival ( OS ) and disease - free survival ( DFS ) rates of HCC patients with high miR-1202 expression were much better than that in low miR-1202 group . - pubmed
A 40 - year - old man was referred to our hospital because of severe anemia and small intestinal tumor revealed by computed tomography . - pubmed
Deep neck space abscesses in children below 5 years of age and their complications . - pubmed
OBJECTIVES : To study the outcomes and complications of deep neck space abscesses in children less than 5 years of age over a period of 15 years . - pubmed
METHODS : A retrospective analysis of children less than 5 years of age with deep neck space abscesses over a 15 - year period was conducted at a tertiary care centre in India . - pubmed
All patients underwent surgical incision and drainage of the abscess and pus cultures were obtained . - pubmed
RESULTS : A total of 510 children less than 5 years of age were identified who were admitted for deep neck space abscess over a 15 - year period . - pubmed
The most common organism isolated in the pus was Staphylococcus aureus ( 21 % ) . - pubmed
Children less than 2 years of age , and those with multiple abscesses or retropharyngeal abscess were more prone to complications . - pubmed
The antioxidant , aged garlic extract , exerts cytotoxic effects on wild - type and multidrug - resistant human cancer cells by altering mitochondrial permeability . - pubmed
Aged garlic extract ( AGE ) has been shown to possess therapeutic properties in cancer ; however its mechanisms of action are unclear . - pubmed
In this study , we demonstrate by MTT assay that AGE exerts an anti - proliferative effect on a panel of both sensitive and multidrug - resistant ( MDR ) human cancer cell lines and enhances the effects of hyperthermia ( 42 C ) on M14 melanoma cells . - pubmed
A cross - sectional study including 66 schizophrenia outpatients compared to 81 healthy controls was undertaken . - pubmed
Despite the progressive nature of Alzheimer ' s disease and other dementias , it is observed that many individuals that are diagnosed with mild cognitive impairment ( MCI ) in one clinical assessment , may return back to normal cognition ( CN ) in a subsequent assessment . - pubmed
Cardiac Effects of Hyperoxia During Resuscitation From Hemorrhagic Shock in Swine . - pubmed
However , we previously showed that hyperoxia attenuated myocardial injury during resuscitation from hemorrhage in swine with coronary artery disease . - pubmed
In conclusion , in contrast to our previous study in swine with coronary artery disease , hyperoxia did not beneficially affect cardiac function or tissue injury in healthy swine , but was devoid of deleterious side effects . - pubmed
All isolated compounds were evaluated for their cytotoxicities against five human cancer cell lines : HL-60 , SMMC-7721 , A-549 , MCF-7 and SW480 in vitro . - pubmed
We recruited 50 PD patients without dementia , no other reasons for cognitive impairment , no condition that could influence evaluation of cognition , olfaction and taste . - pubmed
Olfaction was worse in PD patients with visuospatial dysfunction , while sour and salty identification was worse in those with MCI and executive dysfunction , suggesting different underlying anatomical abnormalities . - pubmed
Mycobacterium ulcerans is the bacillus responsible for Buruli ulcer , an infectious disease and the third most important mycobacterial disease worldwide , after tuberculosis and leprosy . - pubmed
Indeed , a single subcutaneous injection of mycolactone into the mouse footpad induces a long - lasting hypoesthesia up to 48 h. It was suggested that the long - lasting hypoesthesia may result from the persistence of a significant amount of mycolactone locally following its injection , which could be probably due to its slow elimination from tissues . - pubmed
Various quantities of mycolactone were then injected in mouse tissue and hypoesthesia was recorded with nociception assays over a period of 48 h. The hypoesthesia was maximal 6 h after the injection of 4 mug mycolactone . - pubmed
OBJECTIVES : To investigate the preoperative prognostic value of molecular subtypes in relation to clinical information , histopathological findings , and molecular markers for patients with bladder cancer treated with radical cystectomy . - pubmed
A 69 - year - old Japanese woman was admitted to our hospital with progressive muscle weakness and dysphagia . - pubmed
Recent clinical data has presented normalization of factor levels in some patients with improvements in bleed rate and quality of life . - pubmed
Although long - term data is awaited , durable expression has been seen within the hemophilia dog model with no late - toxicity or oncogenesis . - pubmed
Letter by Renu et al Regarding Article , " Frequency of Blood - Brain Barrier Disruption Postendovascular Therapy and Multiple Thrombectomy Passes in Acute Ischemic Stroke Patients " . - pubmed
Cercospora leaf spot ( CLS ) caused by Cercospora canescens is an important disease of cowpea ( Vigna unguiculata ) . - pubmed
Early - Life Iron Deficiency and Its Natural Resolution Are Associated with Altered Serum Metabolomic Profiles in Infant Rhesus Monkeys . - pubmed
BACKGROUND : Iron deficiency is the most common nutrient deficiency in human infants aged 6 to 24 mo , and negatively affects many cellular metabolic processes , including energy production , electron transport , and oxidative degradation of toxins . - pubmed
OBJECTIVES : The objective was to determine how iron deficiency in infancy alters the serum metabolomic profile and to test whether these effects persist after the resolution of iron deficiency in a nonhuman primate model of spontaneous iron deficiency . - pubmed
METHODS : Blood was collected from naturally iron - sufficient ( IS ; n = 10 ) and iron - deficient ( ID ; n = 10 ) male and female infant rhesus monkeys ( Macaca mulatta ) at 6 mo of age . - pubmed
RESULTS : A total of 413 metabolites were measured , with differences in 40 metabolites identified between IS and ID monkeys at 6 mo ( P$\le $ 0.05 ) . - pubmed
A phylogeny based on 37 single - copy genes of the main linear chromosome and rooted with the relapsing fever species Borrelia duttonii strain Ly revealed that strain CA690 T had a sister - group relationship with , and occupied a basal position to , species occurring in North America . - pubmed
BACKGROUND : Primary neuronal cultures are widely used to elucidate fundamental aspects of neuronal anatomy , physiology , cell biology , and neuronal dysfunction in animal models of disease . - pubmed
PURPOSE : To assess the impact of laparoscopic extraperitoneal paraaortic staging in therapeutic planning and prognosis of patients with locally advanced cervical cancer ( LACC ) as compared with imaging staging . - pubmed
Hydrocephalus has been reported in patients with Krabbe disease ; however , it is clinically difficult to monitor for hydrocephalus in patients with Krabbe disease as symptoms of increased intracranial pressure may overlap with symptoms of Krabbe disease . - pubmed
We describe a case series of spontaneous third ventriculostomy and hydrocephalus , likely in response to increased intracranial pressure , in patients with infantile Krabbe disease . - pubmed
METHODS : Brain magnetic resonance images of patients with infantile Krabbe disease were retrospectively analyzed to assess for ventricular size and presence of spontaneous third ventriculostomies . - pubmed
RESULTS : Seventy - five patients with infantile Krabbe disease were evaluated . - pubmed
CONCLUSIONS : Spontaneous third ventriculostomies , likely in the context of increased intracranial pressure , were identified in patients with Krabbe disease . - pubmed
Although difficult to assess , our study highlights the importance of monitoring for increased intracranial pressure , which can result in spontaneous third ventriculostomies , in patients with infantile Krabbe disease . - pubmed
Perioperative myocardial injury risk after elective knee and hip arthroplasty in patients with a high risk of obstructive sleep apnea . - pubmed
BACKGROUND : Myocardial injury after non - cardiac surgery ( MINS ) occurs in approximately 8 - 13 % of patients and has significant 30 - day mortality . - pubmed
Patients with obstructive sleep apnea ( OSA ) suffer recurrent hypoxemia during sleep and surgical patients with OSA are known to have increased risk of cardiorespiratory complications . - pubmed
We hypothesized that patients at high risk for OSA may have an increased risk of MINS . - pubmed
CONCLUSION : The incidence of MINS and postoperative cardiopulmonary complications in patients with elective arthroplasty and a high risk of OSA were low . - pubmed
The assessment of pancreatic exocrine function in patients with inoperable pancreatic cancer : In need of a new gold - standard . - pubmed
BACKGROUND : Pancreatic exocrine insufficiency is commonplace in patients with pancreatic cancer , adversely impacting on quality of life and survival . - pubmed
Nevertheless , a lack of consensus remains about the optimal diagnostic method , specifically in patients with pancreatic cancer . - pubmed
CONCLUSION : Further research is required to identify the most optimal and accurate diagnostic tool to diagnose pancreatic exocrine insufficiency in patients with pancreatic cancer in clinical practice . - pubmed
Clinical Outcome of Edoxaban vs. Vitamin K Antagonists in Patients with Atrial Fibrillation and Diabetes Mellitus : Results from a Multicenter , Propensity - Matched , Real - World Cohort Study . - pubmed
Diabetes mellitus ( DM ) is a chronic metabolic disease which is independently associated with unfavorable clinical outcomes in patients with atrial fibrillation ( AF ) . - pubmed
Few real - world data are available about the clinical performance of non - vitamin K oral anticoagulants ( NOACs ) among patients with atrial fibrillation and diabetes . - pubmed
In this study , we considered patients with AF and diabetes on Edoxaban or VKAs therapy included in the multicenter Atrial Fibrillation Research Database ( NCT03760874 ) . - pubmed
We identified 557 AF patients with diabetes who received Edoxaban ( n : 230 ) or VKAs ( n : 327 ) treatment . - pubmed
Conclusions : Our data support the hypothesis of the safety and efficacy of Edoxaban for use in patients with AF and diabetes , justified by a favorable NCB over VKAs . - pubmed
METHODS : In a series of autopsy - confirmed cases of CBD , we identified patients with cognitive rather than motor predominant features ( CBD - Cog ) , including 5 patients thought to have Alzheimer disease ( AD ) and 10 patients thought to have behavioral variant frontotemporal dementia ( FTD ) . - pubmed
We compared clinical and pathologic features of CBD - Cog with those from a series of 31 patients with corticobasal syndrome ( CBD - CBS ) . - pubmed
CONCLUSION : A subset of patients with CBD has a cognitive predominant syndrome than can be mistaken for AD or FTD . - pubmed
RESULTS : Children had dental caries with mean def - t 6 year old 5.6 + -3.2 , 7 year old 11 + -5.9 , 8 year old 5.8 + -4.0 , 9 year old 3.8 + -1.7 , 10 year old 4.4 + -2.3 , 11 year old 2.5 + -0.7 dan 12 year old 3.0 + -2.7 The def - t was correlated with dietary habits and dental health status . - pubmed
In total , 1,008 pigs ( ~44 kg body weight [ BW ] ) housed in 48 pens by sex , 21 pigs per pen , were fed diets with one of three rye ( var . - pubmed
For the entire trial ( d 0 to 76 ) , pigs fed increasing hybrid rye level substituting wheat grain had decreased ( P < 0.050 ) average daily feed intake ( ADFI ; L 3.05 , M 2.98 , H 2.91 kg / d ) and average daily weight gain ( ADG ; L 1.01 , M 1.00 , H 0.97 kg / d ) . - pubmed
Prophylactic abdominal aortic balloon occlusion ( PAABO ) is a novel and efficient therapy for these patients . - pubmed
METHODS : A total of 48 parturients with PAS were enrolled and divided into two groups . - pubmed
CONCLUSIONS : PAABO reduced perioperative blood loss and the risk of hysterectomy among parturients with PAS . - pubmed
This study aimed to investigate the molecular and clinical characteristics in Thai patients with ACHM . - pubmed
METHODS : Seven unrelated Thai patients with ACHM were recruited . - pubmed
In the blood serum of rabbits receiving an atherogenic diet , the content of cardiolipin involved in the immune mechanisms of atherosclerosis development and a risk factor for thrombosis , sharply increased . - pubmed
Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans . - pubmed
We sought to investigate the impact of preexisting immunity on generation of protective antibody responses to conserved viral epitopes upon influenza virus infection and vaccination in humans . - pubmed
Prophylactic effect of rectal indomethacin plus nitroglycerin administration for preventing pancreatitis after endoscopic retrograde cholangiopancreatography in female patients . - pubmed
In order to contain infection of this highly contagious disease , most of the world population is constrained to live in a complete or partial lockdown for months together with a minimal human - to - human interaction having far reaching consequences on countries ' economy and mental well - being of their citizens . - pubmed
Acute Dose - Dependent Neuroprotective Effects of Poly ( pro-17beta - estradiol ) in a Mouse Model of Spinal Contusion Injury . - pubmed
Following contusive spinal cord injury in adult male mice , poly ( pro - E2 ) films were implanted subdurally and neuroprotection was assessed using immunohistochemistry 7 days after injury and implantation . - pubmed
Left ventriculography with selective coronary angiography was performed on 13 patients with acute myocardial infarcts complicated by cardiogenic shock of left ventricular failure and hypotension . - pubmed
Irreversible ventricular fibrillation resulting in death occurred in one patient 7 - 7 % ) during the opacification of the left coronary artery . - pubmed
Intracellular accumulation of free calcium in mouse tumor cells exposed to anticancer drugs . - pubmed
Alterations in concentrations of intracellular free calcium ( [ Ca2+]i ) were examined in mouse sarcoma S-180 cells exposed to cisplatin , mitomycin C and adriamycin , as related to cell viability . - pubmed
When transgenic mice that do not display the MEN 2 phenotype are crossed to a different background , the progeny display the MEN 2 phenotype . - pubmed
This observation bears special relevance to the human syndrome in that this model system may be used to study the question of penetrance of phenotype . - pubmed
Antibody - dependent enhancement ( ADE ) of hantavirus infections ( strains Hantaan 76 - 118 and SR-11 ) was studied using macrophage - like cell lines ( J774.1 , P388D1 , and U937 ) . - pubmed
These data may be of use as more patients are being considered for recently advocated surgical treatments for impending and established macular hole . - pubmed
To assess differences in hospital course and outcome , the authors studied 8 survivors of sudden death syndrome and 17 patients with preoperative ventricular tachycardia refractory to conventional antiarrhythmic therapy who underwent coronary revascularization and prophylactic implantation of an ICD system in either one or two stages . - pubmed
Patients with advanced coronary disease , poor ventricular function , and silent ischemia received the ICD system in one stage . - pubmed
It was concluded that the prophylactic use of the ICD system is an important adjuvant in the treatment of postoperative malignant arrhythmias for patients undergoing myocardial revascularization . - pubmed
We report on a total of 45 of our most recent patients who underwent penile prosthesis implantation for erectile dysfunction . - pubmed
With recent advances in diagnostic techniques associated with equine lameness , there is a tendency to reduce our reliance on the most important part of purchase evaluation of the horse - the hands - on physical examination . - pubmed
Susceptibility of N'Dama and Boran cattle to tsetse - transmitted primary and rechallenge infections with a homologous serodeme of Trypanosoma congolense . - pubmed
Eight trypanotolerant N'Dama cattle controlled an infection of Trypanosoma congolense ILNat 3.1 transmitted by Glossina morsitans centralis , more efficiently than a group of similarly infected trypanosusceptible Boran cattle . - pubmed
Thus , the trypanotolerant N'Damas controlled a primary infection of T. - pubmed
congolense more efficiently than trypanosusceptible Boran cattle and eliminated a homologous rechallenge infection without the pathology associated with the disease . - pubmed
A double - blind , randomized , cross - over study was carried out on the effect of a sedative and a non - sedative antihistamine on 25 adults with atopic dermatitis . - pubmed
Inherited human prion diseases . - pubmed
Preliminary results of biological tests of the products showed that 8 ( 2 ) , 8 ( 2 )- difluoroprotoporphyrin accumulates to gastric cancer more selectively than other fluorine analogues and that 3 ( 2 ) , 3 ( 2 ) , 8 ( 2 ) , 8 ( 2 )- tetrafluoroprotoporphyrin is taken up by rat hepatoma cells more readily than the others . - pubmed
Metabolic activity of microcarrier attached liver cells after intraperitoneal transplantation during severe liver insufficiency in the rat . - pubmed
Intraperitoneal transplantation of MAL immediately after subtotal hepatectomy resulted in a significantly lower plasma ammonia level , a higher caffeine clearance , a higher urea production and a significantly smaller loss in body weight in comparison to sham transplanted control rats . - pubmed
Care for the child with central nervous system tumors . - pubmed
The anaesthetic management of two patients with severe muscle weakness -- one suffering from acute dermatomyositis , the other from acute polymyositis -- is described . - pubmed
Both patients presented for surgery for malignancy . - pubmed
Ouabain inhibits intracellular pH recovery from acidosis in cultured mouse heart cells . - pubmed
The spectrum of renal histopathology in patients with significant proteinuria in Vanuatu . - pubmed
Three of the 21 patients had evidence of active malaria at the time of presentation , and all of these patients had Plasmodium falciparum . - pubmed
Hematuria in patients with malrotated kidneys . - pubmed
Persistent microscopic hematuria and proteinuria were found in 3 patients with malrotation of the kidneys . - pubmed
This technique definitely adds important clinical information and helps to determine the initial investigations in these patients with congenital anomalies of the kidney complicated by persistent hematuria . - pubmed
Polyacrylamide gel electrophoresis of Loxosceles reclusa venom demonstrated that only one of seven or eight major ( plus three or four minor ) protein components caused necrosis in guinea pig skin . - pubmed
Recognition of syntactic structure in aphasic patients . - pubmed
Accumulation of dopamine by blood platelets from normal subjects and parkinsonian patients under treatment with L - DOPA . - pubmed
Platelets from parkinsonian subjects receiving oral L - DOPA also took up dopamine.3 . - pubmed
In two out of three samples of platelets from parkinsonian subjects , traces of a dopamine - like substance were detected , but this finding requires confirmation.6 . - pubmed
[ Clinical and secondary clinical chemical studies in patients with biliary operations and histologically proven liver damage ] . - pubmed
[ The erythrocyte picture in chronic lung diseases of the horse ] . - pubmed
In the present study , we examined the mechanisms of naloxone 's actions in conscious rabbits made hypotensive by hemorrhage . - pubmed
Naloxone treatment in hypotensive - hypovolemic , conscious rabbits results in an increase in mean arterial blood pressure ( BP ) and a decrease in heart rate ( HR ) . - pubmed
The risks which result from hemodynamic changes after surgery of 35 patients with supratentorial arterio - venous angiomas were investigated . - pubmed
[ Status and treatment of the upper respiratory tract in patients with acute pneumonia ] . - pubmed
Seventeen children with severe asthma received active salbutamol ( 4 mg via a nebuliser , 400 micrograms as an inhalational powder , or a 4 mg tablet ) together with complementary placebos on a double - blind , triple - dummy randomly allocated basis . - pubmed
Immunogenetic analysis of patients with post - schistosomal liver cirrhosis in man . - pubmed
Immune responsiveness of 121 patients with post - schistosomal liver cirrhosis to schistosomal antigens was investigated . - pubmed
The frequency of low responders to schistosomal adult worm antigen was significantly decreased in the patients with post - schistosomal liver cirrhosis ( P less than 0.05 ) . - pubmed
These observations suggested that an HLA - linked immune suppression gene controlled susceptibility or resistance to post - schistosomal liver cirrhosis through regulation of immune responsiveness of the hosts to schistosomal antigen in man . - pubmed
Intact mice demonstrated a dramatic hyperglycemia at 1 h after endotoxin treatment , a response absent in adrenalectomized mice . - pubmed
Plasma glucose levels were significantly reduced from control values at 3 and 6 h posttreatment , with the most pronounced endotoxin - induced hypoglycemia seen in adrenalectomized mice . - pubmed
The efficacy of N - acetylcysteine in preventing doxorubicin - induced cardiomyopathy in dogs . - pubmed
Some ultrastructural aspects of human pathological pelvi - ureteric junction in idiopathic hydronephrosis . - pubmed
Hepatic arteriography in patients with hepatocellular carcinoma : change in findings caused by balloon occlusion of tumor - draining hepatic veins . - pubmed
Accordingly , we studied the change in blood flow visible on hepatic arteriograms when a segment of the hepatic vein is temporarily occluded in patients with hepatocellular carcinoma . - pubmed
MATERIALS AND METHODS : The study group consisted of 24 patients with nodular - type hepatocellular carcinoma . - pubmed
RESULTS : Conventional hepatic arteriography showed the tumor - draining veins to be branches of the portal vein in only two of the 24 patients ( 8 % ) . - pubmed
Hepatic arteriography during venous occlusion , however , showed the tumor - draining veins to be branches of the portal vein in four of the patients ( 17 % ) . - pubmed
An increase in the degree of tumor vascularity with venous occlusion was observed only in a patient with an initial arteriohepatic vein shunt . - pubmed
Dense hepatogram and hepatofugal opacification of the portal vein branches in the occluded , tumor - bearing segment were obtained in 10 patients ( 42 % ) . - pubmed
Eight of these did not have liver cirrhosis , whereas all of the remaining 14 patients did ( p & lt ; .001 ) . - pubmed
A relationship to the undifferentiated primitive neuroectodermal tumours of the central nervous system in children was assumed by the title of these tumours , although it was recognised that they were not necessarily related to peripheral nerves . - pubmed
Identification and characterization of immunodominant antigens during the course of infection with Brucella ovis . - pubmed
OBJECTIVE : This paper compares the effects of goat 's milk and cow 's milk on weight gain and fat absorption , in children with overt malnutrition . - pubmed
One death with candidiasis occurred in the goat 's milk group . - pubmed
Strength in bending was determined for interdental fixation apparatuses applied to hemimandibles obtained from 24 canine cadavers . - pubmed
Hemolytic - uremic syndrome in a six - year - old girl after a urinary tract infection with Shiga - toxin - producing Escherichia coli O103 : H2 . - pubmed
Comparison of the small 16S to 23S intergenic spacer region ( ISR ) of the rRNA operons of some Escherichia coli strains of the ECOR collection and E. - pubmed
Several 16S to 23S spacers of 354 bp have been sequenced from six Escherichia coli strains belonging to the ECOR collection . - pubmed
We have already demonstrated that the final height in GH - deficient children with spontaneous puberty with gonadal suppression therapy by medroxyprogesterone or cyproterone acetate was significantly taller than GHD with spontaneous puberty without gonadal suppression therapy . - pubmed
With a more conservation definition of the syndrome , employing a primary cohort of patients with PTSD of one year or greater duration , brofaromine significantly reduced PTSD symptoms in comparison with placebo . - pubmed
Further study may ultimately define a role for the use of sodium polystyrene sulfonate in the treatment of patients with chronic lithium toxicity . - pubmed
Nineteen patients with RAU ( 12 minor type and 7 major type ) and 8 healthy volunteers , of both sexes , aged 24 - 54 years old were tested . - pubmed
The standard is designed to eliminate or minimize occupational exposure to Hepatitis B Virus ( HBV ) , Human Immunodeficiency Virus ( HIV ) and other bloodborne pathogens . - pubmed
[ Hepatitis B virus reactivation after allogeneic bone marrow transplantation in a patient previously cured of hepatitis B ] . - pubmed
We report a case in a patient with natural immunity to hepatitis B who had undergone allogenic bone marrow transplantation with an identical sibling donor one year before for the chronic myelogenous leukemia in the first chronic phase . - pubmed
The clinical effect of faropenem was evaluated in 165 ambulatory patients with various infections in the field of obstetrics and gynecology at 10 institutions in Yamagata Prefecture . - pubmed
The significance of the time course of ST segment elevation just after reperfusion therapy for acute myocardial infarction was investigated in 25 consecutive patients with acute myocardial infarction and ST elevation . - pubmed
To examine auto - antibody production in periodontitis patients , Western immunoblotting with human gingival fibroblasts was performed . - pubmed
Immuno - reactivity against human gingival fibroblasts was examined with sera from 30 periodontitis patients and 10 periodontally healthy subjects . - pubmed
In this study we present an analysis of 11 patients presenting congenital bilateral absence of the vas deferens ( CBAVD ) . - pubmed
METHODS : Serum TTV - DNA was studied in spouses of 41 subjects with TT viremia . - pubmed
New information promises to clarify some of the complex issues of the physiological roles of estrogen and the contribution of estrogen to the development of neoplastic diseases in humans . - pubmed
The influence of age at exposure to radiation on cancer risk in humans . - pubmed
Human histologic evaluation of a bone graft combined with GTR in the treatment of osseous dehiscence defects : a case report . - pubmed
SUBJECTS & amp ; METHODS : The subjects were five patients with IBM confirmed pathologically . - pubmed
The purpose of the present study was to elucidate the relative effectiveness of several PMN agonists in stimulating lysosomal - enzyme secretion and leukotriene ( LT ) B ( 4 ) production by PMNs isolated from diabetic subjects . - pubmed
It is surprising that PMNs from these same diabetic subjects responded normally after stimulation with A23187 , serum - opsonized zymosan , or phorbol myristate acetate . - pubmed
RESULTS : Restenosis was found in 23 ( 24 % ) patients within the first 6 months . - pubmed
Multivariate analysis revealed a significantly reduced risk for restenosis in these patients compared to patients without the short allele ( odds ratio 0.2 , 95 % Cl 0.06 to 0.70 , p = 0.007 ) . - pubmed
[ Assessment of long - term bone metabolism in patients with relative hypoparathyroidism after changing the calcium concentration of the dialyzate to 3mEq / L ] . - pubmed
Factors involved include the increasing number of older and diabetic patients initiating dialysis . - pubmed
In conclusion , the use of a 3 mEq / l dialysate calcium may improve hypoparathyroidism in a substantial number of patients , avoiding the untoward effect that lower calcium concentration has on bone mineralization . - pubmed
We studied the hypercholesterolemic rabbit model in order to evaluate potentials of regression of arteriosclerosis by measuring various blood and plaque parameters . - pubmed
We tested the hypothesis that two glasses of red wine , taken together with the noon meal , would cause postprandial reduction in blood pressure in hypertensive individuals . - pubmed
Eighty - eight thyrotoxic lactating mothers and their infants were studied . - pubmed
Serum MMI was measured in the infants of thyrotoxic mothers taking 20 - 30 mg MMI . - pubmed
Mean+/-SD of free T4 index ( FT4I ) in thyrotoxic mothers treated with 20 and 30 mg MMI for one month decreased from 20.1+/-4.2 to 9.7+/-1.5 ( p<0.001 ) and from 20.6+/-4.8 to 8.6+/-3.0 ( p<0.001 ) , respectively . - pubmed
The dose of MMI was adjusted and thyroid function remained normal up to 12 months of MMI therapy in thyrotoxic lactating mothers . - pubmed
Bisphenol A ( BPA ) , an environmental estrogen derived from the plastic industry , was given orally via incorporation into the food of 30 male and female polecats at 3 different doses ( 10 , 50 , or 250 mg / kg body weight / day ) for 2 wk with 10 animals acting as controls . - pubmed
We report the case of a 31 - year - old woman who delivered twins by Caesarean section in whom atonic uterine haemorrhage developed 6 h postoperatively . - pubmed
During conservative treatment with the high - dose prostaglandin analogs sulprostone ( PGE ( 2 ) ) and dinoprost ( PGF ( 2alpha ) ) , acute pulmonary oedema and cardiac decompensation developed and , subsequently , the patient suffered cardiopulmonary arrest . - pubmed
Despite 2h of CPR , the patient was discharged from hospital 3 months later without any major physical or neurocognitive deficit . - pubmed
METHODS : Clinical data of 37 PBC patients together with pathological findings of 20 PBC patients were reviewed . - pubmed
Liver biopsy in 20 PBC patients mainly found : fibrosis in 17 cases ( 85 % ) , interlobular bile duct lesions in 13 ( 65 % ) , lobular mononuclear inflammation in 13 ( 65 % ) , lymphocytic hepatocellular piecemeal necrosis in 10 ( 50 % ) , and bile pigment accumulation in 9 ( 45 % ) . - pubmed
CONCLUSIONS : PBC is mostly found in middle - aged women . - pubmed
The impact of parasitism by Asobara tabida on Drosophila melanogaster larval development , survival features and larval activity has been investigated using two strains of the parasitoid . - pubmed
ZOSTER MENINGOENCEPHALITIS IN A STEROID - TREATED PATIENT . - pubmed
Breast carcinoma is the most common carcinoma in women in Europe and its early diagnosis and treatment is important for the overall survival of the patients . - pubmed
Mitral regurgitation in patients with advanced systolic heart failure . - pubmed
BACKGROUND : Mitral regurgitation ( MR ) may develop in patients with advanced systolic congestive heart failure ( CHF ) without organic mitral valve disease and contribute to worsening symptoms and survival . - pubmed
Surgical mitral annuloplasty improves symptoms in patients with advanced CHF , and percutaneous approaches to mitral annuloplasty are being developed . - pubmed
Our objective was to define the prevalence , clinical correlates , and prognostic implications of functional MR and the use of mitral annuloplasty in patients with advanced systolic CHF evaluated in a heart failure clinic . - pubmed
Of 716 patients with advanced CHF , 558 had satisfactory baseline echocardiograms performed at our institution . - pubmed
The severity of MR was confirmed by quantitative analysis in 72 % of patients with hemodynamically significant MR ( more than moderate ) . - pubmed
Patients with hemodynamically significant MR had higher mortality ( P=.03 ) but not when controlling for age , sex , cause , New York Heart Association class , and ejection fraction ( P=.95 ) . - pubmed
CONCLUSION : Among patients with advanced CHF , hemodynamically significant MR is common . - pubmed
A feline lymphoblastoid cell line ( KO-1 ) was established from a 5 - year - old neutered female cat with naturally occurring thymic lymphoma . - pubmed
MATERIALS AND METHODS : From 1980 to 2003 we identified 5 patients with urinary matrix stones referred to our tertiary medical center for evaluation and treatment . - pubmed
Scientifically based training methods are now being applied in rehabilitation of patients after stroke and trauma , and in the sensory retraining techniques currently applied in the treatment of focal hand dystonia as well as in sensory re - education after nerve repair in hand surgery . - pubmed
Increased carrageenan - induced acute lung inflammation in old rats . - pubmed
Consistent with the biochemical markers of inflammation , increased lung damage , as assessed by nitrosative stress and lipid peroxidation , was observed in carrageenan - treated old rats . - pubmed
Therefore , the use of Vitex doniana to control postpartum bleeding after child birth may be justified . - pubmed
Mesalazine and/or Lactobacillus casei in preventing recurrence of symptomatic uncomplicated diverticular disease of the colon : a prospective , randomized , open - label study . - pubmed
GOALS : To investigate the effectiveness and safety of mesalazine , with or without Lactobacillus casei , in preventing recurrence of symptomatic diverticular disease of the colon . - pubmed
Ninety consecutive patients ( 36 men , 54 women , mean age 67.5 y , range 39 to 84 y ) , previously affected by symptomatic uncomplicated diverticular disease of the colon ( remission obtained with rifaximin 800 mg / d plus mesalazine 2.4 g / d for 10 d , followed by mesalazine 1.6 g / d for 8 wk ) , were enrolled in a 12 - month follow - up . - pubmed
RESULTS : Eighty - five patients completed the study ( 94.5 % ): 2 patients ( 2.22 % , 1 of group M and 1 of group LM ) were withdrawn from the study for protocol violation and 1 ( 1.11 % ) for hospital admission due to acute pulmonary disease ( group L ) ; 2 patients ( 2.22 % ) were lost to follow - up . - pubmed
Only 10 patients ( 11.1 % ) showed recurrence of symptoms ( overall symptomatic score : 68 ) . - pubmed
Transplantation of fetal dopaminergic ( DA ) neurons can produce symptomatic relief for patients with Parkinson ' s disease , but the technical and ethical difficulties have limited the application of this therapy . - pubmed
Monkey ESCs give rise to midbrain DA neurons , and the transplanted ESC - derived neurospheres function as DA neurons , attenuating the neurological symptoms of the monkey Parkinson ' s disease model . - pubmed
Between 1995 and 2001 , 17 patients received IORT for soft tissue sarcomas of the extremities . - pubmed
Two patients experienced locoregional relapses , six patients recurred at metastatic sites , and one patient died without recurrence . - pubmed
For patients with soft tissue sarcomas of the extremities , IORT used as a boost to EBRT provides excellent local control , with limited acute toxicities . - pubmed
METHODS : We studied 13 patients ( mean age + /- 1 SD , 57 + /- 11 years ) with pulmonary carcinoid tumours . - pubmed
All patients demonstrated a single pulmonary lesion . - pubmed
None of the patients had recurrent carcinoid disease or died during follow - up ( 864 + /- 218 days ) . - pubmed
Mediastinal lymph node metastases or extrathoracic metastases were not detected in any patient . - pubmed
CONCLUSIONS : Clear lens extraction was an effective and predictable surgery to reduce myopias and an apparently safe procedure in patients with and without prophylactic preequatorial retinal photocoagulation . - pubmed
METHODS : Eligible patients were identified from the Dutch AIDS Therapy Evaluation , The Netherlands ( ATHENA ) national observational cohort . - pubmed
Patients can experience ARVS , the risk for development of resistance after treatment interruption is realistic , and there is a potential hazard of HIV transmission to sexual partners . - pubmed
The procedure involves several rounds of the following three steps , starting from an allogeneic human ES cell line : the creation of tetraploid ES cells by fusion of somatic cells from the prospective PS with the ES cells , the differentiation of these cells into tetraploid oogonia that give rise to diploid oocytes following meiosis , and the isolation of ES cells from parthenogenetic blastocysts , morula , 8 - cell embryos , or 4 - cell embryos derived from these oocytes . - pubmed
The rSVV established latent infection in neural ganglia . - pubmed
A subsequent study will evaluate the ability of rSVV vaccines expressing SIV antigens to protect nonhuman primates against simian AIDS . - pubmed
This chapter also illustrates the methods that can be used to test hypoxia - inducible gene expression in vitro and in vivo , including hypoxia treatment of cultured cells , generation of murine ischemic heart models , and analysis of gene expression . - pubmed
OBJECTIVE : This study was undertaken to analyze the outcome of children with DKA treated with a modified protocol at a tertiary level teaching hospital PICU in Pune , Maharashatra . - pubmed
METHODS : We retrospectively analyzed case records of 12 patients ( 8 males and 4 females ) with DKA ( 11 new and 1 readmission ) admitted in our PICU from January 2005 to June 2006 . - pubmed
Acute aldosterone infusion enhances thrombosis development in normotensive rats . - pubmed
Role of distinct immune components in the radiation - induced abrogation of systemic lupus erythematosus development in mice . - pubmed
The New Zealand Black x New Zealand White F1 [ ( NZB / NZW ) F1 ] mouse develops an autoimmune condition resembling aspects of human systemic lupus erythematosus ( SLE ) . - pubmed
Kidney lesions were milder and autoantibody levels were lower in irradiated mice . - pubmed
Thus , a role for B-1 cells in murine SLE can not be excluded , since the irradiation protocol did not effectively eliminate these cells . - pubmed
Previous studies have demonstrated that Madin - Darby canine kidney ( MDCK ) epithelial cells form cysts when grown in a three - dimensional ( 3D ) extracellullar matrix ( ECM ) environment . - pubmed
Applying strict clinical - laboratory criteria , 6 patients were diagnosed clinically with PTMA and treated with plasma exchange . - pubmed
Clinical variables , including underlying disease , conditioning regimen , stem cell donor status , duration and serum level of cyclosporine , infections , and acute graft versus host disease were compared statistically in patients with histologic signs of PTMA ( n=8 ) with those without PTMA ( n=12 ) . - pubmed
RESULTS : PTMA was verified histologically in all 6 patients with a clinical diagnosis of PTMA but only 2 of the 14 patients who were not clinically diagnosed had histologic evidence of PTMA ( P<0.0001 ) . - pubmed
RESULTS : After the first interim evaluation of 101 patients , the study was stopped because of a significant increase in temporary ipsilateral vocal cord motility dysfunction in the retrojugular access group ( 31 % vs. 6 % , p=0.0014 ) . - pubmed
No other significant differences concerning major complications ( death or stroke ) , other cranial nerve injuries , wound healing , or patient satisfaction was observed neither in the early postoperative phase nor at follow up . - pubmed
CONCLUSION : Due to the high incidence of temporary ipsilateral vocal cord dysfunction in patients undergoing retrojugular exposure of the carotid artery , we recommend the conventional ventrojugular approach , which can be performed by incision along the anterior border of the sternomastoid muscle or by transversal skin incision . - pubmed
The present study aimed to clarify the order of changes in IMCL levels and skeletal muscle mitochondrial function during the development of type 2 diabetes in Zucker diabetic fatty ( ZDF ) rats . - pubmed
Fa / fa ZDF rats were studied at 3 different ages corresponding to different stages of type 2 diabetes , whereas fa/+ rats served as controls . - pubmed
In vivo muscle oxidative capacity was not different in fa / fa animals compared to controls , and in vitro enzyme activity data suggested improved functionality of enzymes involved in fat oxidation in type 2 diabetic animals . - pubmed
Accordingly , we can conclude that in the ZDF rat model , type 2 diabetes develops in the absence of skeletal muscle mitochondrial dysfunction . - pubmed
We describe a 50 - year - old woman with recurrent neurologic deficits . - pubmed
METHODS : Bile was aspirated during endoscopic retrograde cholangiopancreatography in consecutive patients with MBO . - pubmed
RESULTS : Among 60 patients with MBO , 16 ( 26.7 % ) had white bile . - pubmed
A few weeks earlier the man underwent an elective operation for an upper quadrant tumor in the right lung . - pubmed
DATA SOURCES : Searches were conducted to identify all published randomized , placebo - controlled , double - blind clinical trials available for review by May 2007 on the efficacy of continuation or maintenance treatment of major depressive disorder with either selective serotonin reuptake inhibitors ( SSRIs ) or tricyclic antidepressants ( TCAs ) that included patients entering a maintenance phase after achieving remission from the acute phase . - pubmed
METHODS : A retrospective study of consecutive patients with systemic sclerosis and fecal incontinence was performed . - pubmed
Results of the antimycobacterial assays indicated that the minimal inhibitory concentrations ( MICs ) and minimal bactericidal concentrations ranged from 1.22 microg / mL to 39.06 microg / mL for Mycobacterium smegmatis and all studied Mycobacterium tuberculosis strains for the crude extract from D. - pubmed
tuberculosis H37Rv strain was observed at Day 18 for D. - pubmed
Results of the antigonorrhoeal assay indicated that diospyrone was able to prevent the growth of all studied strains of Neisseria gonorrhoeae . - pubmed
Major postoperative complications occurred in 23 ( 26 % ) patients , including nine ( 10 % ) patients requiring reoperative treatment due to skin flap necrosis , wound infection , hematoma , or fascial dehiscence . - pubmed
Fourteen patients presented with commotio retinae . - pubmed
CONCLUSION : Contusion may increase ACD particularly in the peripheral region even in patients who have no apparent manifestations in the anterior ocular segment . - pubmed
In this communication we describe a young woman who presented with a severe inflammatory illness that consequently developed into pyoderma gangrenosum , anterior tibialis myositis and arthritis that were all antecedent to the intestinal involvement . - pubmed
Nonalcoholic steatohepatitis , animal models , and biomarkers : what is new ? - pubmed
Nowadays , there are numerous mice models to study abnormal liver function such as steatosis , NASH , and hepatocellular carcinoma . - pubmed
The study of the established animal models has provided many clues in the pathogenesis of steatosis and steatohepatitis , although these remain incompletely understood and no mice model completely fulfills the clinical features observed in humans . - pubmed
[ The clinical feature , diagnosis and management of splenic artery aneurysms in liver transplant patients ] . - pubmed
CONCLUSIONS : Morbidity of SAA is higher in patients of liver cirrhosis . - pubmed
Extract from seeds and bark of horse chestnut ( Aesculus hippocastanum L ) is used as an herbal medicine against chronic venous insufficiency . - pubmed
The aim of this study was to investigate the effects and mechanisms of action of horse chestnut on the contraction of bovine mesenteric veins and arteries , and human platelet aggregation . - pubmed
ADP - induced human platelet aggregation was significantly reduced by horse chestnut . - pubmed
Human platelet aggregation is reduced by horse chestnut . - pubmed
OBJECTIVE : This study investigates the effectiveness of the Newborn Individualized Developmental Care and Assessment Program ( NIDCAP ) on neurobehavioral and electrophysiological functioning of preterm infants with severe intrauterine growth restriction ( IUGR ) . - pubmed
STUDY DESIGN : Thirty IUGR infants , 28 to 33 weeks gestational age , randomized to standard care ( control / C=18 ) , or NIDCAP ( experimental / E=12 ) , were assessed at 2 weeks corrected age ( 2wCA ) and 9 months corrected age ( 9mCA ) in regard to health , anthropometrics , and neurobehavior , and additionally at 2wCA in regard to electrophysiology ( EEG ) . - pubmed
CONCLUSION : This is the first study to show NIDCAP effectiveness for IUGR preterm infants . - pubmed
OBJECTIVE : Mild cognitive impairment ( MCI ) is a syndrome thought to be a prodrome of dementia for some patients . - pubmed
One subtype , amnestic MCI ( aMCI ) , may be specifically predispose patients to develop Alzheimer ' s dementia ( AD ) . - pubmed
METHODS : One thousand seven hundred seventy - nine participants in the National Alzheimer 's Coordinating Center ( NACC ) with MCI were included in this study . - pubmed
All participants were evaluated systematically with a thorough cognitive battery , clinical interview , and consensus diagnoses , and subtyped as : ( 1 ) amnestic ( aMCI ) ( single- or multiple - domain ) versus non - amnestic ( non - aMCI ) ; ( 2 ) executive dysfunction - MCI ( exMCI ) ( single- or multiple - domain ) versus no executive dysfunction - MCI ( non - exMCI ) ; ( 3 ) both aMCI and exMCI ; and ( 4 ) neither aMCI nor exMCI . - pubmed
BACKGROUND : Although numerous biomarkers may be prognostically meaningful in patients with acute dyspnea , few comparative analyses have addressed possible associations between a wide range of candidate biomarkers and clinical variables . - pubmed
A final risk model was derived , and this model was then validated by applying it to patients from a separate cohort of acutely dyspneic patients . - pubmed
Comparative evaluation of chemotoxicity and phototoxicity using Mel - HEV and CPZ ( as positive control ) was performed on mouse fibroblast cell line ' Balb / c 3T3 ' . - pubmed
Low - dose methotrexate and azathioprine are the most useful immunosuppressive drugs and are indicated in patients with of failure or contra - indication of corticosteroids or in those patients who needs a long term prednisone dose higher than 10 mg daily to control the sarcoidosis . - pubmed
Infliximab can be useful in some severe sarcoidosis patients refractory to classical treatment , except for cardiac involvement . - pubmed
Time delay between symptom and surgery in patients with carotid artery stenosis . - pubmed
A total of 142 carotids in 139 patients with symptomatic stenoses between 2002 and 2006 were included . - pubmed
There are several measures to improve the chain of procedures for patients with carotid artery stenosis . - pubmed
The criteria address structural , process and human resource requirements and medical aspects for the accreditation of various level of trauma centre . - pubmed
CONCLUSION : There is a great opportunity to apply best practice criteria to improve the care of trauma in South Africa and improve patient outcome . - pubmed
Porcine teschovirus polioencephalomyelitis in western Canada . - pubmed
Beginning in 2002 , a small number of pig farms in western Canada began reporting 4 - 7 - week - old pigs with bilateral hind - end paresis or paralysis . - pubmed
Low numbers of pigs were affected , some died , most had to be euthanized , and those that survived had reduced weight gains and neurological deficits . - pubmed
To the authors ' knowledge , this is the first report of teschovirus encephalitis in western Canada and the first reported case of polioencephalomyelitis in pigs in Canada , where teschovirus was confirmed as the cause . - pubmed
BACKGROUND / AIMS : EBV has been associated with Burkitt lymphoma ( BL ) . - pubmed
It establishes a latent infection but its reactivation has been observed in patients receiving long - term chemotherapy . - pubmed
Fermented soybean liquid ( FSL ) has been well cited for its broad spectrum of biological effects , yet its documented gastropeptic ulcer ( GPU ) ameliorating effect is still lacking . - pubmed
METHODS : The authors analysed 70 patients with PMR , 20 with GCA , and 24 healthy controls ( HC ) . - pubmed
CONCLUSION : Myrsinane - type diterpene Proliferin A from Euphorbia prolifera shows cytotoxic effect against human ovarian cancer cell line A2780 . - pubmed
We describe the management of interrupted aortic arch associated with coronary artery disease through single - stage surgical procedure without cardiopulmonary bypass in a 56 - year - old woman . - pubmed
RESULTS : Ninety - two patients survived from a total 163 patients with VAP during the course of their confinement in the intensive care unit . - pubmed
Multivariable logistic regression analysis identified that a pre - existing Charlson Comorbidity Index score ( P = .011 ) , initial oxygenation index ( P = .025 ) , SOFA score ( P = .043 ) , VAP caused by Acinetobacter baumanii ( P = .030 ) , and infection with MDR pathogens ( P = .003 ) were independent risk factors for hospital mortality in patients with VAP . - pubmed
CONCLUSION : High Charlson Comorbidity Index score , high initial oxygenation index , high SOFA score , and infection with Acinetobacter baumannii or MDR pathogens significantly affect hospital mortality in patients with VAP . - pubmed
A CCl ( 4 )-induced liver fibrosis model in mice was also utilized . - pubmed
The authors report the rare case of a 58 - year - old man with segmental arterial mediolysis ( SAM ) with associated intracranial and intraabdominal aneurysms , who suffered subarachnoid hemorrhage ( SAH ) due to rupture of an intracranial aneurysm . - pubmed
The patient presented with severe headache and vomiting . - pubmed
Ninety - six patients ( 96/181 , 53.0 % ) were reported to have thyroid disease . - pubmed
Surgical management of thyroid disease was performed in 80.2 % ( 77/96 ) of patients with thyroid disease , with total thyroidectomy being the most common operation reported ( 23/77 , 29.9 % ) . - pubmed
CONCLUSION : Careful monitoring of thyroid disease in CS patients is imperative . - pubmed
To investigate the anti - asthmatic effects of CF and their underlying mechanism , we examined the influence of CF on the development of pulmonary eosinophilic inflammation and airway hyperresponsiveness in a mouse model of allergic asthma . - pubmed
Postnatal effects of prenatal nicotine exposure on body weight , brain size and cortical connectivity in mice . - pubmed
The current study uses a prenatal nicotine mouse model to determine effects of PNE on body weight , brain weight , brain length and development of neocortical circuitry , including thalamocortical afferents ( TCAs ) and intraneocortical connections ( INCs ) . - pubmed
Interestingly , the reduction of body weight , brain weight , and brain length observed in newborn PNE mice compared to control mice was no longer present at postnatal day ( P ) 10 . - pubmed
The risk of coughing increased with tobacco smoking and the number of sticks smoked per day . - pubmed
Campylobacter jejuni is the major worldwide cause of bacterial gastroenteritis . - pubmed
We studied the 2 - year outcome of deep - brain stimulation at the ventral anterior limb of the internal capsule and ventral striatum for 4 patients with treatment - resistant OCD . - pubmed
Alveolar echinococcosis is a parasitic infectious disease caused by the larval stage of Echinococcus multilocularis , which is one of the two most important species of Echinococcus . - pubmed
Protective effects of Galla Rhois , the excrescence produced by the sumac aphid , Schlechtendalia chinensis , on transient focal cerebral ischemia in the rat . - pubmed
Oral administration of GRE ( 300 mg / kg ) in a transient focal cerebral ischemia rat model ( two hours of occlusion followed by 22 hours of reperfusion ) reduced the brain infarct volume by 37.5 % . - pubmed
In conclusion , GRE had potent radical - scavenging activities and neuroprotective effects in a rat model of stroke when it was pre- and co - administered . - pubmed
Biopsies of 7 patients with LB were stained before and after azithromycin treatment . - pubmed
Seven of 8 patients with leiomyosarcoma with follow - up had recurrence within the follow - up period , whereas there were no recurrences in patients with cellular leiomyoma . - pubmed
METHODS : The menstrual bleeding pattern was registered in fertile women undergoing open - heart surgery in 2010 - 12 . - pubmed
Haematocrit and 24 - h postoperative bleeding were compared with those of men undergoing cardiac surgery . - pubmed
Unplanned menstrual bleeding ( lasting 2 - 5 days ) was detected in 13 ( 60 % ) patients . - pubmed
Ten women took oral contraceptives , 8 of whom had unexpected menstrual bleeding during admission . - pubmed
Men ( n = 22 ) , with a mean age of 35 ( range 17 - 54 ) years , had mean bleeding of 331 ( range 160 - 796 ) ml postoperatively , which was not statistically significantly different from the women 's . - pubmed
Streptococcus tigurinus is highly virulent in a rat model of experimental endocarditis . - pubmed
Streptococcus tigurinus is responsible for systemic infections in humans including infective endocarditis . - pubmed
tigurinus in humans correlated with an increased ability to induce IE in rats . - pubmed
tigurinus strains AZ _ 3a(T ) , AZ_4a , AZ _ 8 and AZ _ 14 , isolated from patients with infective endocarditis or with the well known IE pathogen Streptococcus gordonii ( Challis ) . - pubmed
Aortic infection was assessed after 24 h. S. - pubmed
tigurinus AZ_3a(T ) , AZ_4a and AZ _ 14 produced endocarditis in & gt;=80 % of rats whereas S. - pubmed
Multi - institutional validation of a preoperative scoring system which predicts survival for patients with glioblastoma . - pubmed
Glioblastoma is the most common and aggressive type of primary brain tumor in adults . - pubmed
Of the 334 patients in this study from three different institutions , the preoperative factors found to be negatively associated with survival in a Cox analysis were age & gt;60 years ( p<0.0001 ) , Karnofsky Performance Scale score & lt;=80 ( p=0.03 ) , motor deficit ( p=0.02 ) , language deficit ( p=0.04 ) , and periventricular tumor location ( p=0.04 ) . - pubmed
METHODS : We retrospectively reviewed HBUS reports in traumatic brain injury ( TBI ) patients admitted to our tertiary neuro - critical care unit ( NCCU ; January 2005 - June 2011 ) . - pubmed
We included patients receiving an HBUS for isolated LFTs derangement , excluding pre - existing hepato - biliary diseases or trauma . - pubmed
CONCLUSIONS : In TBI patients , HBUS did not appear sensitive in detecting causes for isolated LFT abnormalities . - pubmed
CASE PRESENTATION : A 63 - year - old Hispanic man presented with prostatism of several months ' evolution . - pubmed
This is illustrated here through studies on PEMs as synthetic vaccine candidates targeting the malaria parasite and the human immunodeficiency virus type-1 ( HIV-1 ) . - pubmed
METHODS AND RESULTS : We report the case of a 42 - year - old female with OOM caused by a hemangiopericytoma of the left ethmoid sinus . - pubmed
Anisakis morphotype I is the principal etiologic agent of human anisakiasis , with differences in pathogenicity found between the Anisakis simplex s.s . - pubmed
( 93 and 91 % lower , respectively ) , they may still be implicated in human anisakiasis , as they are capable of attaching to and penetrating the gastrointestinal wall of animals , demonstrating a similar pathogenicity to that of A. - pubmed
The pathogenesis of bleomycin - induced lung injury in animals and its applicability to human idiopathic pulmonary fibrosis . - pubmed
Bleomycin , an anti - neoplastic agent that causes lung fibrosis in human patients has been used extensively in rodent models to mimic IPF . - pubmed
In this review , we compare the pathogenesis and histological features of human IPF and bleomycin - induced pulmonary fibrosis ( BPF ) induced in rodents by intratracheal delivery . - pubmed
SUBJECTS AND METHODS : CAP was diagnosed in patients ( 6 men aged 19 - 24 years and 1 woman aged 49 years ) on the basis of clinical , laboratory , and radiological findings . - pubmed
However , BAdV-3 infection of cells transfected with 100K - enhanced yellow fluorescent protein - expressing plasmid detected fluorescent protein in the nucleus of the cells , suggesting that other viral proteins may be required for the nuclear localization of 100K. - pubmed
Several studies have used window of opportunity in breast cancer patients before neoadjuvant chemotherapy to correlate gene expression analysis , metabolomics , immunohistochemical markers , and metabolic serum markers with those likely to benefit . - pubmed
We review the role metabolite measurement , functional imaging and gene sequencing analysis play in elucidating the effects of metabolically targeted drugs in cancer treatment and determining patient selection . - pubmed
BACKGROUND : Hypoglycemia is concerning in patients with diabetes undergoing hyperbaric oxygen ( HBO2 ) therapy . - pubmed
RESULTS : During 77 months , 3,136 HBO2 sessions were performed on patients with diabetes . - pubmed
CONCLUSIONS : In patients with diabetes undergoing HBO2 , severe hypoglycemia is rare and occurs more frequently in Type 1 diabetes . - pubmed
The lymphoma cells were also positive for Epstein - Barr virus by Epstein - Barr virus - encoded RNA in situ hybridization test . - pubmed
CLINICAL CASES : We report 5 cases of patients who experienced intrathoracic rupture of hydatic cyst of liver . - pubmed
This case report supports the feasibility of using this combination therapy early after allo - HSCT for patients with HCV infection . - pubmed
Piperine , a natural compound isolated from the fruits of Piper , is known to modulate several neurotransmitter systems such as serotonin , norepinephrine , and GABA , all of which have been linked to the development of convulsions . - pubmed
Fruits of Piper species have been suggested as means for managing seizure disorders . - pubmed
Furthermore the latency for development of convulsions and mortality rate was recorded in different experimental mouse models of epilepsy ( pentylenetetrazole , maximal electroshock , NMDA , picrotoxin , bicuculline , BAYK-8644 , strychnine - induced convulsions ) after administration of various doses of piperine ( 5 , 10 and 20 mg / kg , i.p . ) - pubmed
BACKGROUND : The powdery mildew disease affects thousands of plant species and arguably represents the major fungal threat for many Cucurbitaceae crops , including melon ( Cucumis melo L. ) , watermelon ( Citrullus lanatus L. ) and zucchini ( Cucurbita pepo L. ) . - pubmed
Gene transfer strategies to the brain have contributed to evaluate in animal models many interesting tracks , some of which should deserve clinical applications in AD patients in the future . - pubmed
Radiation Monitoring Results from the First Year of Operation of a Unique Ambulance - based Computed Tomography Unit for the Improved Diagnosis and Treatment of Stroke Patients . - pubmed
To determine if health outcomes of possible stroke patients can be improved by decreasing the time from symptom presentation to treatment , the first mobile stroke ambulance unit in the United States was deployed by The University of Texas Health Science Center at Houston ( UTHealth ) in 2014 , equipped with a computed tomography imaging system . - pubmed
The mobile stroke unit shortens the time to treatment for stroke patients by allowing pre - hospital treatment . - pubmed
This report , based on data from a clinical case , proposes that pulmonary tumor thrombotic microangiopathy , an underdiagnosed cause of pulmonary hypertension and death in patients with adenocarcinoma , is a paraneoplastic syndrome ( PNS ) . - pubmed
One patient died of sepsis and aspiration pneumonia at 3 months . - pubmed
Conduction disease accounted for most devices , but 371 patients underwent CIED implantation for secondary prevention of ventricular arrhythmias . - pubmed
The limited literature showed comparable patient HRQOL profiles to those with benign conditions such as degenerative disc disease . - pubmed
Treatment of post - traumatic elbow deformities in children with the Ilizarov distraction osteogenesis technique . - pubmed
OBJECTIVE : The present study assessed functional and radiographic outcomes of distraction osteogenesis treatment of post - traumatic elbow deformities in children . - pubmed
METHODS : Eight children were treated between 2008 and 2013 for post - traumatic elbow deformities using distraction osteogenesis . - pubmed
Six patients had varus and 2 had valgus deformity . - pubmed
Mean preoperative varus deformity in 6 patients was 29.2 and valgus deformity in 2 patients was 28.5 . - pubmed
CONCLUSION : Ilizarov distraction osteogenesis is a valuable alternative in treatment of elbow deformities in children . - pubmed
This review will describe the pathophysiology of cancer pain and general approach in managing a patient with lung cancer pain . - pubmed
Whole Genome Sequence and Comparative Genomics of the Novel Lyme Borreliosis Causing Pathogen , Borrelia mayonii . - pubmed
Borrelia mayonii , a Borrelia burgdorferi sensu lato ( Bbsl ) genospecies , was recently identified as a cause of Lyme borreliosis ( LB ) among patients from the upper midwestern United States . - pubmed
A high - throughput , modified ALS activity assay for Cyperus difformis and Schoenoplectus mucronatus seedlings . - pubmed
HCV infection was confirmed by positive results in HCV antibody ( anti - HCV ) and HCV - RNA tests . - pubmed
However , atypical surface ECGs can also be found in patients with severe left ventricular dysfunction and involvement of the right ventricle complicating the diagnosis of bundle branch reentry VT . - pubmed
It is important to diagnose bundle branch reentry VT because patients with bundle branch reentry VT may suffer from a high rate of serial implantable cardioverter defibrillator ( ICD ) interventions based on VT recurrences due to immediate reinitiation of the arrhythmia . - pubmed
Nusinersen is globally the first drug approved ( by the US FDA ) for treatment of SMA in children and adults . - pubmed
METHODS : We collected 24 - h urine samples from 114 controls and 71 patients with adrenal diseases . - pubmed
Compared with patients with adrenocortical adenoma ( ACA ) , patients with adrenocortical carcinoma ( ACC ) had 11 steroids with increased Z scores , especially tetrahydro-11 - deoxycortisol ( 14 vs 0.5 , P & lt ; 0.001 ) , pregnanetriol ( 7.5 vs -0.4 , P = 0.001 ) , and 5 - pregnenetriol ( 5.4 vs -0.4 , P = 0.01 ) . - pubmed
METHODS : Two German university hospitals with different EVD management regimes ( rapid weaning [ RW ] vs gradual weaning [ GW ] ) pooled the data of their observational cohorts containing altogether 1171 consecutive SAH patients treated between January 2005 and December 2012 . - pubmed
RESULTS : The final cohort consisted of 455 and 510 SAH survivors treated in the centers with RW and GW , respectively . - pubmed
Shunt - dependent SAH patients undergoing GW required significantly longer time until shunting ( mean 29.8 vs 21.7 d , P & lt ; .001 ) and hospital stay ( mean 39 vs 34.4 d , P = .03 ) . - pubmed
Danshen , the dried root of Salvia miltiorrhiza Bunge ( Lamiaceae ) , is one of the traditional Chinese medicines ( TCMs ) most commonly used for the treatment of cardiovascular and cerebrovascular diseases . - pubmed
We aimed to determine on patients with CAD the relationships between Trans fatty acids ( Trans FA ) and different CAD associated parameters such as inflammatory and oxidative stress parameters in addition to Gensini score as a vascular severity index . - pubmed
METHODS : Fatty acid profiles were established by gas chromatography from 111 CAD patients compared to 120 age - matched control group . - pubmed
Plasmatic and erythrocyte Trans FA were also increased in CAD patients compared to controls . - pubmed
The measurement of these Trans FA would be of great value for the screening of lipid metabolism disorders in CAD patients . - pubmed
METHODS : A total of 103 depressive patients and 32 healthy subjects were assessed . - pubmed
According to HAMD-17scores , 51 , 18 , and 34 patients were enrolled in the mild depression , moderate depression , and severe depression groups , respectively . - pubmed
Toxicity of plant extracts containing pyrrolizidine alkaloids using alternative invertebrate models . - pubmed
Introduction : Lyme disease is a tick - borne illness caused by the spirochete Borrelia burgdorferi and is widely reported in the USA , Central Europe , South East Asia and Latin America . - pubmed
The Physical and Neurological Examination of Subtle Signs was preliminarily examined for sensitivity to motor changes in a pilot cohort of adolescents aged 13 - 17 yrs with sports - related concussion . - pubmed
A total of 15 adolescents ( 5 female adolescents ) with sports - related concussion were evaluated up to three times : within 2 wks of injury , approximately 1 mo later ( mean , 35 days between visits ) , and for those not recovered at the second visit , again after clinical recovery ( mean , 70 days between the first and last visits for all participants ) . - pubmed
Efficacy of Idursulfase therapy in patients with Mucopolysaccharidosis type II who initiated enzyme replacement therapy in adult age . - pubmed
BACKGROUND : Enzyme replacement therapy ( ERT ) has been shown to decrease urine glycosaminoglycans ( uGAGs ) and liver and spleen volumes , and to improve clinical symptoms in mucopolysaccharidosis type II ( MPS - II ) patients . - pubmed
CONCLUSIONS : ERT improves uGAGs and liver / spleen volume with a moderate evidence level in MPS - II patients initiating therapy as adults , although the putative associated clinical benefit is unclear . - pubmed
Real life efficacy and safety of this combination were evaluated in HCV GT1b infected patients ( mostly cirrhotics ) with compensated liver disease who failed previous boceprevir or telaprevir based therapies more than a year before . - pubmed
Material and methods : Data of previous protease inhibitor failure patients , treated with 3DAA+RBV for 12 weeks ( GT1b and/or non - cirrhotics ) or 24 weeks ( non - GT1b cirrhotics ) , were retrospectively collected . - pubmed
Conclusions : One year after previous failure of boceprevir or telaprevir based therapy , 12 weeks of 3DAA+RBV combination in HCV GT1b infected patients is similarly effective and safe as in those with no previous HCV therapy , even in the presence of cirrhosis . - pubmed
Not all kidney disease in patients with diabetes is diabetic nephropathy . - pubmed
Gualoupi ( Pericarpium Trichosanthis ) injection in combination with convention therapy for the treatment of angina pectoris : a Meta - analysis . - pubmed
OBJECTIVE : To use a Meta - analysis to review the efficacy and safety of Gualoupi ( Pericarpium Trichosanthis)injection ( PTI ) in the treatment of angina pectoris . - pubmed
MATERIAL / METHODS : Thirty adult subjects clinically and radiographically diagnosed with knee osteoarthritis , who were not previously subjected to any treatment , were enrolled . - pubmed
METHODS : A total of 1444 women with EC were identified . - pubmed
Of which we extracted women with locoregional and distant recurrence or with distant recurrence alone . - pubmed
RESULTS : 110 women developed distant metastatic disease with ( n = 37(33.6 % ) ) or without ( n = 73(66.4 % ) ) locoregional recurrence , including 39 women with exclusive first site of metastatic disease and 34 women with multiple sites of metastatic disease . - pubmed
When considering all women , the most common exclusive first site of metastasis was lung ( 42.8 % ) . - pubmed
These data support current clinical practice of screening for site - specific metastatic disease after initial treatment of early stage EC based on concerning women - specific signs or symptoms . - pubmed
We performed a systematic review and meta - analysis of studies investigating vessel density ( VD ) in patients with glaucoma using OCTA . - pubmed
Camembert cheese was manufactured from milk contaminated with pathogenic and nonpathogenic strains of Escherichia coli . - pubmed
Human epidemiological studies suggested that vitamin D3 deficiency might increase glioma incidence , but molecular mechanism is less understood . - pubmed
The most frequent ailment for which antibiotics are prescribed is otitis media ( ear infections ) , which is most commonly caused by Haemophilus influenzae , Moraxella catarrhalis , and Streptococcus pneumoniae Treatment of otitis media is complicated by the fact that the bacteria in the middle ear typically form biofilms , which can be recalcitrant to antibiotic treatment . - pubmed
Furthermore , bacterial respiratory infections can be greatly exacerbated by viral coinfection , which is particularly evidenced by the synergy between influenza and S. - pubmed
pneumoniae In this study , we sought to ascertain the in vivo efficacy of aminomethyl spectinomycin lead 1950 , an effective antibacterial agent both in vitro and in vivo against Streptococcus pneumoniae in the context of complex respiratory infections and acute otitis media . - pubmed
BACKGROUND : The aim of this study was to evaluate the role of the skeletal muscle mass index ( SMI ) for major postoperative morbidity in patients with Crohn ' s disease ( CD ) and intestinal surgery at a tertiary referral center . - pubmed
METHODS : A retrospective analysis of the prospectively maintained database for surgical patients with CD at our institution was performed . - pubmed
Major postoperative complications were observed in 32 patients ( 13.9 % ) . - pubmed
Anticarcinogenic potential of gold nanoparticles synthesized from Trichosanthes kirilowii in colon cancer cells through the induction of apoptotic pathway . - pubmed
This protocol afforded well - defined nanoparticles possessing a drug loading of approximately 7 % w / w. The resulting Nal - cNPs demonstrated excellent biocompatibility , while exhibiting sustained linear release kinetics in vitro and blocking the effects of high dose ( 10 mg / kg ) acute morphine for up to 98 h in an in vivo rodent model of neuropathic pain . - pubmed
Furthermore , 10 patients in Group B had SCL , compared with none in Group A ( p = 0.004 ) . - pubmed
Only 4 patients ( 7 % ) cited postoperative activity limitations as being caused by hip pain . - pubmed
All patients were followed regarding treatment response , treatment duration , and presence of relapse . - pubmed
Prognosis was good for all patients , but relapse was significantly more frequent in the high SP - D group ( 6 cases ) than in the normal SP - D group ( 0 cases ; P = 0.049 ) . - pubmed
Pseudomonas aeruginosa exhibits resistance against many antibiotics and causes a variety of infections in immunocompromised individuals and especially in those with burn wounds and lung infections . - pubmed
Triflumuron induces genotoxicity in both mice bone marrow cells and human colon cancer cell line . - pubmed
To reach this purpose , our study aimed to elucidate the eventual genotoxic effects of TFM in mice bone marrow cells and in HCT 116 cells after a short term exposition . - pubmed
TFM was administered intraperitoneally to Balb / C male mice at doses of 250 , 350 and 500 mg / kg bw for 24 h. Genotoxicity was monitored in bone marrow cells using the comet test , the micronucleus test and the chromosome aberration assay . - pubmed
This genotoxicity was confirmed also in vitro on human intestinal cells HCT 116 using the comet test . - pubmed
PURPOSE : To test the effectiveness ( Participant A ) and tolerability ( Participant B ) of urinary stone comminution in the first - in - human trial of a new technology , burst - wave lithotripsy ( BWL ) , Materials and Methods : An investigational BWL and ultrasonic propulsion system was used to target a 7 - mm kidney stone in the operating room prior to ureteroscopy ( Participant A ) . - pubmed
CONCLUSIONS : The first - in - human tests of BWL pulses were successful in that a renal stone was comminuted in under 10 minutes , and BWL was also tolerated by an awake subject for a distal ureteral stone . - pubmed
We report a case of a patient with brain stem cavernous malformations presented as pure COPS with additional sensory disturbance in the thorax . - pubmed
We included 202 patients ( 73.48 + - 13.1 years ) with various systemic metabolic disorders for training of the DNN model , and the following groups for validation of the model : ( 1 ) Patient group , 65 patients ( 73.6 + - 11.0 years ) who were hospitalized for rehabilitation after stroke ; ( 2 ) Healthy group , 37 subjects ( 62.0 + - 8.6 years ) ; ( 3 ) Health examination group , 165 subjects ( 54.0 + - 8.6 years ) admitted for a health examination . - pubmed
METHODS : The effect of moclobemide on seizures was assessed in the electroconvulsive threshold test , while its influence on antiepileptic drugs was estimated in the maximal electroshock test in mice . - pubmed
So far as the results of experimental studies can be transferred to clinical conditions , moclobemide seems safe for the application in patients with epilepsy and depression . - pubmed
Angiographic evaluation of patients with chronic gastrointestinal bleeding . - pubmed
The compound was mutagenic in both tester strains used , namely TA98 and TA100 . - pubmed
The clinical picture and treatment of exacerbated chronic respiratory insufficiency is studied in 189 silicosis patients with different stage and degree of decompensation . - pubmed
It is found out that chronic respiratory insufficiency determination in these patients is conditioned by the exacerbation of a chronic inflammtory process in the bronchi and lungs ( 68.2 per cent ) , or by intercurrent acute inflammtory pulmonary process ( 15.9 per cent ) . - pubmed
Lethality in patients with III degree silicosis amounts to 8,2 per cent , and in patients with III degree respiratory insufficiency -- to 30.7 per cent . - pubmed
A complex active therapy program for silicosis patients with exacerbated chronic respiratory insufficiency is proposed . - pubmed
Using an in vitro quantitative clonal culture technique of bone marrow granulocyte - macrophage progenitor cells ( colony - forming units culture ( CFU - c ) ) , we studied the hematopoietic toxicity of azathioprine after unilateral and bilateral ureteral ligation , unilateral and bilateral nephrectomy , and splenectomy in C57BL / 6 mice . - pubmed
When the ocular toxicity and the in vivo and in vitro effects of gentamicin , Nebcin , and saline solution were compared in experimentally induced Pseudomonas keratitis in rabbits , both antibiotics showed the same toxicity for the rabbits ' conjunctival tissues . - pubmed
Two hundred sixty - seven strains of Pseudomonas aeruginosa isolated from clinical specimens were immunotyped using seven anti - Pseudomonas rabbit sera , and pyocin typed using eight indicator strains . - pubmed
An approach to effective therapy for patients suffering such reactions should be based on our latest understanding of the pathophysiology of this syndrome . - pubmed
This study comprised 12 patients admitted for interpleural catheter treatment of chronic pancreatic pain . - pubmed
Catheters were left in situ for 12 - 30 h. Immediate pain relief was achieved in all patients . - pubmed
Five patients had only a single blockade offering pain relief for a median of 33 days . - pubmed
One patient suffering from pancreatic carcinoma remained pain - free until death 45 days later . - pubmed
After this second blockade long - lasting pain relief was achieved in three patients for 70 , 105 and 145 days . - pubmed
Two patients experienced pain relief lasting 11 - 14 days , while in two patients only a short - lived effect was observed , 3 - 8 days . - pubmed
Unimportant pneumothorax occurred in one patient . - pubmed
We consider interpleural blockade an alternative worth further investigations in the future in the treatment of patients suffering from chronic pancreatic pain . - pubmed
It is known that consumption of cruciferous vegetables protects against the chemical induction of cancer in many organs . - pubmed
The use of sufentanil in neuroanesthesia has been questioned because of a potential increase in intracranial pressure ( ICP ) in dogs and humans . - pubmed
Toxoplasmosis in sheep , goats and cattle in central Ethiopia . - pubmed
In a seroepidemiological survey using an indirect haemagglutination assay , the prevalence rate of toxoplasmosis in central Ethiopia was 22.9 % of 899 sheep , 11.6 % of 753 goats and 6.6 % of 785 cattle . - pubmed
Favorable effects of prostacyclin infusion in a patient given a renal transplant and with severe vascular disease secondary to diabetes -- a case report . - pubmed
Microangiopathy is one of the most frequent diseases in diabetic patients . - pubmed
A diabetic man with a kidney transplant and with severe and progressive vasculopathy with early necrosis of the fingers and toes was submitted to three prostacyclin ( PGI2 ) intravenous infusions ( 5 ng / kg / min for forty - eight hours ) during a period of two months . - pubmed
Combination of parenteral and oral immunotherapy in grass pollen - allergic children . - pubmed
The psychological care of children with malignant disease . - pubmed
Cholesterol esterification and net mass transfer of cholesterylesters and triglycerides in plasma from healthy subjects and hyperlipidemic coronary heart disease patients . - pubmed
A three - year clinical comparison of a sodium monofluorophosphate dentifrice with sodium fluoride dentifrices on dental caries in children . - pubmed
Human tissues ( keloid , small bowel , lung ) were fixed in either Carnoy 's fluid or neutral buffered formalin . - pubmed
Normotensive rats were adrenalectomized or sham - operated and made hypertensive with methylprednisolone acetate ( 20 mg / kg s.c . - pubmed
[ Blood serum analyses in cow herds with fertility disturbances ] . - pubmed
Toxicity in the dog of inhaled 90 Y in fused clay particles : early biological effects . - pubmed
Respiratory tract carcinogenesis induced in hamsters by different dose levels of benzo -( a ) pyrene and ferric oxide . - pubmed
Effect of fluorides on root resorption in replanted rat molars . - pubmed
Arthritis was produced in rats by the intravenous injection of Mycoplasma arthritidis . - pubmed
An avirulent strain of M. - pubmed
arthritidis and a strain previously classified as M. - pubmed
Fractionation of Marek ' s disease virus - induced lymphoma by velocity sedimentation and association of infectivity with cellular fractions with and without tumor antigen expression . - pubmed
Cell suspensions of lymphomas induced by Marek ' s disease ( MD ) virus were fractionated by sedimentation at unit gravity on a continuous gradient of bovine fetal serum . - pubmed
Growth and maturation of children with insulin - dependent diabetes mellitus . - pubmed
A 67 - year - old man had a spontaneous intrastromal iris hemorrhage which resolved without complications . - pubmed
Evaluation of the safety of metoclopramide in patients with gastroesophageal reflux disease . - pubmed
The long - term safety of metoclopramide was evaluated for up to 30 months in 269 patients with chronic symptoms of gastroesophageal reflux disease . - pubmed
Tympanosclerosis of the ear drum in children with SOM differs from normal ear drums in children with SOM . - pubmed
Profound calcification could only be found in children with tympanosclerosis coexisting with chronic perforation of the ear drum . - pubmed
Among 2493 patients undergoing cerebral angiography 43 children were found to have cerebrovascular occlusion . - pubmed
Fifty - six patients who had undergone salvage surgery for residual or recurrent squamous carcinomas of the tongue between 1967 and 1977 were reviewed . - pubmed
The tongue or cervical lymph nodes were involved in 27 of the 28 patients who died with recurrent tumour . - pubmed
By treatment with high dose prednisolone and intense supportive therapy the patient underwent complete remission of AIL with preservation of the remaining renal function . - pubmed
From 1984 to 1989 , 354 patients with a diagnosis of testis tumor were referred to the Oncology Hospital , Ankara , Turkey , for therapy . - pubmed
Histologic diagnoses were typical seminoma in 33 patients , anaplastic seminoma in two patients and spermatocytic seminoma in only one patient . - pubmed
Reduced dose PVB chemotherapy can be successfully and safely used as the primary treatment of choice in patients with Stage IIC - IV testicular seminoma . - pubmed
Two elderly patients with polymyalgia rheumatica ( PMR ) , one with and the other without temporal arteritis ( TA ) , are presented . - pubmed
Intraoperative complications of laparoscopic surgery are mostly due to traumatic injuries sustained during blind trocar insertion and physiological changes associated with patient positioning and pneumoperitoneum creation . - pubmed
Laparoscopic cholecystectomy is a major advance in the management of patients with symptomatic gall - bladder disease . - pubmed
We reviewed 22 epidermoid and 10 dermoid tumours of the skull and brain from patients operated on consecutively at Henry Ford Hospital between 1975 and 1991 . - pubmed
The average age at presentation was 35 years for patients with epidermoids and 15 years for those with dermoids . - pubmed
Common clinical presentations for patients with intradural lesions included headache , visual deficits , and seizures , whereas patients with extradural lesions harbored asymptomatic scalp masses . - pubmed
Overall , with the intradural tumours we had good to excellent results in 17 patients ( 90 % ) , poor results in 1 ( 5 % ) , and 1 death ( 5 % ) . - pubmed
Re - operation was needed in 5 intradural recurrences ( 26 % ) with deterioration in only one patient 's neurologic status postoperatively . - pubmed
Indices of heterogeneity in mosquito susceptibility to infection indicated that gene frequencies determining susceptibility fluctuated with time in all species , except A. - pubmed
Salmonella enteritidis 27655 - 3b and a few diarrheagenic Escherichia coli strains produce morphologically and antigenically related , thin , aggregative fimbriae , collectively named GVVPQ fimbriae ( S. K. Collinson , L. Emody , T. J. - pubmed
enteritidis strains and six E. - pubmed
Treatment of pulmonary congestion and control of heart rate in patients with atrial fibrillation remain major medical goals . - pubmed
Percutaneous balloon commissurotomy is preferred for most patients with predominant mitral stenosis and for those with contraindications to valve replacement . - pubmed
Implantation of a prosthetic valve is best for patients with significant mitral regurgitation , multivalve disease , associated coronary artery disease that requires bypass , or mitral valve deformity too severe to allow adequate balloon commissurotomy . - pubmed
Newborns were highly hypoxemic at admission and all but one underwent rescue cannulation . - pubmed
Atrial fibrillation in acute myocardial infarction : a prospective study based on data from a consecutive series of patients admitted to the coronary care unit . - pubmed
Ischaemia -- reperfusion injury in the rat is modulated by superoxide generation and leads to an augmentation of the hypoxic pulmonary vascular response . - pubmed
The study population was 21 women with suspected placental insufficiency ; one woman was excluded because of a positive OCT with reactive fetal heart rate pattern . - pubmed
Late virus replication events in microglia are required for neurovirulent retrovirus - induced spongiform neurodegeneration : evidence from neural progenitor - derived chimeric mouse brains . - pubmed
CasBrE is a neurovirulent murine retrovirus which induces a spongiform myeloencephalopathy in susceptible mice . - pubmed
The role of calcium ions entering cells upon both reperfusion and previous ischemia for reperfusion arrhythmias has been studied on the experimental model of isolated rat right ventricle perfused through coronary artery . - pubmed
Up to 65 % of elderly hospitalized patients are protein - energy undernourished at admission or acquire nutritional deficits while hospitalized . - pubmed
Calcium binding to polypeptides of rat liver and Zajdela hepatoma mitochondrial inner membranes . - pubmed
Large intravenous bilirubin loads increase the cytotoxicity of bile and lower the resistance of the canalicular membrane to cytotoxic injury and cause cholestasis in pigs . - pubmed
METHODS : The cytotoxicity of bile was assayed against pig erythrocytes before and throughout 4.5 - h intravenous infusion of 170 microg kg(-1 ) body weight of bilirubin in anaesthetized pigs . - pubmed
The abnormal behaviors induced by methamphetamine ( MAP : 1 mg / kg ) or phencyclidine ( PCP : 10 mg / kg ) were measured using behavioral analysis following the microinjection of one of three calcium ( Ca ) antagonists ( nifedipine : Nif , nicardipine : Nic and flunarizine : Flu ) into the rat caudate putamen or amygdala . - pubmed
Computed tomography of cholesterinic granulomas in the choroid plexus of horses . - pubmed
Cholesterinic granulomas are tumor - like masses in the choroid plexuses of horses . - pubmed
This report describes the computed tomographic findings in four horses with cholesterinic granulomas , including the clinical and the pathologic features . - pubmed
All four horses had bilateral cholesterinic granulomas in the lateral ventricles . - pubmed
METHODS : Between 1995 and 1998 , we performed an interventional radiological treatment in five patients with idiopathic portal hypertension , four of whom had refused surgery and one of whom had undergone surgery . - pubmed
Three patients with gastroesophageal varices ( GEV ) were treated by partial splenic embolization ( PSE ) , one patient with esophageal varices ( EV ) and massive ascites by transjugular intrahepatic portosytemic shunt ( TIPS ) and PSE , and one patient with GEV by percutaneous transhepatic obliteration ( PTO ) . - pubmed
RESULTS : In one woman with severe GEV who underwent three sessions of PSE , there was endoscopic confirmation that the GEV had disappeared . - pubmed
PTO for GV in one patient resulted in good control of the varices . - pubmed
All patients have survived for 16 - 42 months since the first interventional treatment , and varices are well controlled . - pubmed
CONCLUSION : Interventional radiological treatment is effective for patients with idiopathic portal hypertension , whether or not they have undergone surgery . - pubmed
Estrogen synthesis in human colon cancer epithelial cells . - pubmed
Genetic evidence for obesity loci involved in the regulation of body fat distribution in obese type 2 diabetes rat , OLETF . - pubmed
The Otsuka Long - Evans Tokushima Fatty ( OLETF ) rat is an animal model for obese type 2 diabetes in human . - pubmed
Obesity is essential for the onset of type 2 diabetes in this rat . - pubmed
Our present investigation was designed to identify quantitative trait loci ( QTLs ) contributing to obesity by performing a whole - genome search using 214 F(2 ) intercross progeny between OLETF and F344 rats . - pubmed
The CBA / N strain carries xid , a murine btk missense mutation that reduces peripheral B cell numbers . - pubmed
We report a case study of a patient with bilateral amygdaloid damage who , despite a severe deficit in interpreting facial expressions of emotion including fear , exhibits an intact ability to express this and other basic emotions . - pubmed
Resistance of Pseudomonas aeruginosa isolates to hydrogel contact lens disinfection correlates with cytotoxic activity . - pubmed
One of the most common pathogens in infection of hydrogel contact lens wearers is Pseudomonas aeruginosa , which can gain access to the eye via contamination of the lens , lens case , and lens care solutions . - pubmed
Resistance to disinfection appeared to be an inherent rather than acquired trait , since some resistant strains had been isolated prior to the introduction of the disinfectants and some susceptible P. - pubmed
At the follow - up , 290 children still had headache , 101 were in clinical remission , and 51 had dropped out . - pubmed
Broccoli sprouts are a rich source of glucosinolates and isothiocyanates that induce phase 2 detoxication enzymes , boost antioxidant status , and protect animals against chemically induced cancer . - pubmed
Antiplasmodial activities of some Ghanaian plants traditionally used for fever / malaria treatment and of some alkaloids isolated from Pleiocarpa mutica ; in vivo antimalarial activity of pleiocarpine . - pubmed
Fourteen Ghanaian plants used in folk medicine to treat fever / malaria were screened for activity against Plasmodium falciparum ( strain K1 ) and were tested for general toxicity to the brine shrimp . - pubmed
Possible toxicity due to U. - pubmed
Although ( 1 ) was inactive against malaria parasites in vitro , it was moderately active against P. - pubmed
berghei in mice ( 25 mg kg(-1 ) daily for 4 days reduced parasitaemia by 28.5 % compared to untreated controls ) . - pubmed
The present report describes 3 patients with systemic lupus erythematosus who developed typical symptoms of acquired angioedema , characterized by recurrent swelling of subcutaneous and mucous tissues . - pubmed
MATERIALS AND METHODS : PJ34 ( at doses of 0.03 - 30 mg / kg ) was tested in rats and mice subjected to standard models of inflammation , with relevant parameters of inflammation measured using standard methods . - pubmed
PJ34 treatment ( oral gavage ) induced a significant suppression of the inflammatory response in dextran sulfate colitis , multiple low dose streptozotocin diabetes and cyclophosphamide - accelerated autoimmune diabetes in the non - obese diabetic mice , and reduced the degree of mononuclear cell infiltration into the iris in an endotoxin - induced uveitis model . - pubmed
OBJECTIVES : To identify which children with acute otitis media are at risk of poor outcome and to assess benefit from antibiotics in these children . - pubmed
RESULTS : Distress by day three was more likely in children with high temperature ( adjusted odds ratio 4.5 , 95 % confidence interval 2.3 to 9.0 ) , vomiting ( 2.6,1.3 to 5.0 ) , and cough ( 2.0 , 1.1 to 3.8 ) on day one . - pubmed
Among the children with high temperature or vomiting , distress by day three was less likely with immediate antibiotics ( 32 % for immediate v 53 % for delayed , chi2=4.0 ; P=0.045 , number needed to treat 5 ) as was night disturbance ( 26 % v 59 % , chi2=9.3 ; P=0.002 ; number needed to treat 3 ) . - pubmed
In children without higher temperature or vomiting , immediate antibiotics made little difference to distress by day three ( 15 % v 19 % , chi2=0.74 ; P=0.39 ) or night disturbance ( 20 % v 27 % , chi2=1.6 ; P=0.20 ) . - pubmed
CONCLUSION : In children with otitis media but without fever and vomiting antibiotic treatment has little benefit and a poor outcome is unlikely . - pubmed
We have examined the pattern of four radiation - related neoplasms in a radiation - exposed cohort of 2795 patients . - pubmed
A severe model of mesenteric ischemia and reperfusion was produced by subjecting mice to 45 min occlusion followed by reperfusion of the superior mesenteric artery and celiac trunk . - pubmed
The aim of this paper is to review new developments in the intensive care of patients with space - occupying middle cerebral artery infarctions . - pubmed
Corticoids and hemodilution are obsolete therapies in these patients . - pubmed
To minimize hypertension and provide reversibility , 24 red wolves were immobilized using three medetomidine - butorphanol ( MB ) combinations without the use of ketamine in the initial injection . - pubmed
The heart rate was similar among the three groups for the first 30 min , and marked bradycardia was noted in one wolf from each group . - pubmed
The MBK30 wolves had significant elevations in heart rate and transient hypertension after intravenous ketamine administration . - pubmed
Most wolves had mild to moderate metabolic acidemia . - pubmed
STUDY DESIGN : We reviewed the clinical data of 98 patients with ICC who underwent resection at Seoul National University Hospital from 1980 to 1998 . - pubmed
In the developing rat hippocampus , ictal epileptiform activity can be elicited easily in vitro during the first three postnatal weeks . - pubmed
Based on the theories of accumulated temperature and on the physio - ecological characteristics of Medicago sativa , a simulation model for its growth under soil water stress in arid sandy region was developed . - pubmed
Intracellular magnesium of platelets in children with diabetes and obesity . - pubmed
By using a fluorescent probe , mag - fura-2 , we examined the basal levels and changes in intracellular Mg ( 2 +)([ Mg ( 2 +)]( i ) ) of platelets in diabetic and obese children . - pubmed
The diabetic patients and obese subjects have [ Mg ( 2 +)]( i ) deficiency . - pubmed
Macrometastases ( dimensions greater than 2 mm ) were found in 19 patients . - pubmed
In another seven of these patients ( 36.8 % ) , macrometastases were found in SLNs with radioactive levels lower than 51 % of that of the hottest node . - pubmed
Cell death unlikely contributes to taxol production in fungal elicitor - induced cell suspension cultures of Taxus chinensis . - pubmed
Cell suspension cultures of Taxus chinensis , with 20 , 40 and 100 mg fungal elicitor l(-1 ) from Aspergillus niger , underwent rapid cell death after 24 h , which was about 2 , 3.7 and 5 - fold of that of the control . - pubmed
O2 - free N2 inhibited cell death but had little effect on Taxol production as induced by 40 mg fungal elicitor l(-1 ) . - pubmed
Chicken - pox is one more newer vaccine in our armamentarium against infectious diseases . - pubmed
Anti gizzard ulcer factors in the treatment of gastric ulcer in man ; a review . - pubmed
[ USE OF AMINAZIN IN THE TREATMENT OF PNEUMONIA IN YOUNG CHILDREN ] . - pubmed
[ DIAGNOSIS , THERAPY , DOCUMENTATION AND CLINICAL EVALUATION OF 360 WOMEN WITH NEOPLASTIC DISEASE IN GYNECOLOGICAL DIVISION OF A STATE HOSPITAL ] . - pubmed
Action of antiinflammatory agents on endotoxin - induced lung inflammation in mice . - pubmed
Anaesthesia in elderly patients with neurodegenerative disorders : special considerations . - pubmed
Neurodegenerative diseases are increasingly common in elderly patients , who present a particular anaesthetic challenge . - pubmed
The majority of people over the age of 70 years have some degree of cerebral atrophy . - pubmed
Levodopa , bromocriptine and tricyclic antidepressants are known to cause orthostatic hypotension in patients with neurodegenerative disease . - pubmed
For induction of general anaesthesia propofol is a suitable agent in patients with neurodegenerative disease due to its rapid metabolism , but may not be suitable in patients with Parkinson ' s disease as it can induce spontaneous involuntary movements . - pubmed
Regional anaesthesia may , however , have significant advantages in patients with Parkinson ' s disease , who can continue to take oral levodopa preoperatively , during surgery , if required , and early in the postoperative period . - pubmed
Anti - emetic drugs such as phenothiazines , butyrophenones and metoclopramide should be used carefully in the postoperative period in these patients as their antidopaminergic effects may induce or exacerbate parkinsonian effects . - pubmed
PATIENTS : Seventy - seven children ( mean age , 6.5 years ; range , 6 months-16 years ) referred consecutively for sexual abuse evaluation between July 1999 and June 2002 were included . - pubmed
A patient presented with hypertension , hypokalemia , and a 1.2 - cm left adrenal tumor . - pubmed
The controlled - environment chamber : a new mouse model of dry eye . - pubmed
CONCLUSIONS : This study indicates that exposure of normal mice to a low - humidity environment in a CEC can lead to significant alterations in tear secretion , goblet cell density , and acquisition of dry eye - related ocular surface signs . - pubmed
OBJECTIVES : To report an unusual presentation of a spinal cord injury , examine the approach to reversal of the injury , and review the treatment and management controversies of acute cervical facet dislocations in specific patient subgroups . - pubmed
CONCLUSIONS : This case report highlights the advantages and shows some safety concerns regarding immediate , closed traction reduction of cervical facet dislocation with real - time neural monitoring in an awake , alert , oriented , and appropriately select patient before MRI studies in the setting of preexisting central stenosis from OPLL . - pubmed
NE-4C stem cells , however , did not migrate towards the tumour , if implanted near to Gl261 tumours established in the adult mouse forebrain . - pubmed
Evaluation of microarray analysis for predicting treatment responsiveness in patients with chronic hepatitis C viral infection . - pubmed
More than one sleep pathology may be present in a particular patient , and these disorders may interact to increase the severity or prolong the duration of sleep disturbance . - pubmed
Expression of carbohydrate antigens in human esophageal squamous cell carcinoma : prognostic application and its diagnostic implications . - pubmed
In this study , the relevance of carbohydrate antigen expression profile was examined in esophageal squamous cell carcinoma together with prognosis in 130 patients . - pubmed
The 5 - year survival rate of patients was found to be associated with expression of sialyl Le ( a ) and sialyl Le ( x ) antigens and with MVD ; thus , all of them were revealed to be independent prognostic factors . - pubmed
Correlation between carotid area calcifications and periodontitis : a retrospective study of digital panoramic radiographic findings in pretreatment cancer patients . - pubmed
In 10 randomized controlled trials involving 2,602 patients , no incidence of stent fracture was recognized or reported . - pubmed
The angiograms of all 530 patients who underwent repeat angiography were analyzed to identify the presence of stent fracture . - pubmed
RESULTS : Stent fracture was identified in 10 patients . - pubmed
Adverse clinical outcomes associated with stent fracture occurred in 7 patients ( 6 patients had binary restenosis and 1 patient had stent thrombosis ) , all necessitating repeat intervention . - pubmed
OBJECTIVE : Leishmania tropica is the causative agent of anthroponotic cutaneous leishmaniasis ( CL ) in Iran . - pubmed
The therapeutic effect and the efficiency of a new method for the extraction of a removable metallic stent were examined in three patients treated for oesophageal perforation . - pubmed
Two of the three patients were dilated with a balloon catheter because of corrosive oesophageal stenosis , and the oesophagus was perforated . - pubmed
PATIENTS AND METHODS : Prevalence of major International AIDS Society - USA HIV-1 drug resistance mutations was measured over calendar years in a population with treatment failure and undergoing resistance testing . - pubmed
The current report addresses the complex genotype - phenotype interactions in an azoospermic man . - pubmed
OBJECTIVES : To evaluate the efficacy , safety and tolerability of aliskiren in elderly patients ( & gt ; or = 65 years old ) with essential hypertension . - pubmed
METHODS : In this double - blind , multicenter study , 355 elderly patients with hypertension [ office mean sitting systolic blood pressure ( msSBP ) & gt ; or = 145-<180 mmHg and mean 24 - h ambulatory systolic BP ( ASBP ) & gt ; or = 135 mmHg ] were randomized to once - daily treatment for 8 weeks with aliskiren 75 mg ( n = 91 ) , 150 mg ( n = 84 ) , 300 mg ( n = 94 ) or the comparator lisinopril 10 mg ( n = 86 ) . - pubmed
A 71 - year - old man was admitted to our hospital because of constipation and bloody stool . - pubmed
After IR , myocardial apoptosis and infarct size were significantly reduced in hearts of exercised animals compared with sedentary controls . - pubmed
Antinociceptive activity of Buddleja globosa ( matico ) in several models of pain . - pubmed
ETHNOPHARMACOLOGICAL RELEVANCE : Leaf extracts of Buddleja globosa ( Buddlejaceae ) are used in Chilean folk medicine for wound healing . - pubmed
METHODS AND RESULTS : Patients with AF undergoing electrical cardioversion were randomized to receive candesartan 8 mg once daily ( n = 58 ) or matching placebo ( n = 66 ) and no additional class I or III anti - arrhythmic drugs . - pubmed
Risk for AF recurrence was similar in patients with low ( 64 % ) , intermediate ( 75 % ) , or high on - treatment rates ( 63 % , P = 0.446 ) and was also independent of candesartan effects on the fibrillatory rate . - pubmed
CONCLUSION : In patients with persistent AF , candesartan decreases the fibrillatory rate , but this effect is restricted to patients with high baseline fibrillatory rates and is not associated with improved cardioversion outcome . - pubmed
We describe the case of a child ( " S " ) who was treated with radiation therapy at age 5 for a recurrent malignant brain tumor . - pubmed
Twelve patients had very large or multicentric glioblastoma multiforme with a poor performance status and received TMZ plus radiation doses of 45 - 50.4 Gy . - pubmed
Twenty - three patients would have been eligible for randomisation in the European Organisation for Research and Treatment of Cancer / National Cancer Institute of Canada ( EORTC / NCIC ) trial comparing combined and adjuvant TMZ plus radiation against radiotherapy alone . - pubmed
METHODS : The case histories and MR / MR angiography findings of 4 patients with PCAH were examined . - pubmed
GOALS : Compare patient characteristics and outcome and also physician referral patterns between surgically and nonsurgically managed patients with pancreatic pseudocysts . - pubmed
PATIENTS : All patients treated for pancreatic pseudocyst between 1999 and 2005 were identified in our health services database . - pubmed
Patients treated surgically and endoscopically were similar in terms of age ( 49 vs. 52 y ) , mean cyst diameter ( 9.1 vs. 9.5 cm , P=0.74 ) , incidence of chronic pancreatitis ( 50 % vs. 32 % , P=0.26 ) and complicated pancreaticobiliary disease ( 69 % vs. 60 % ) . - pubmed
Human glioblastoma is well known for its capacity to interfere with effective antitumor immune responses . - pubmed
The paper evaluates the intensity of peritoneal adhesions induced by talc administration on Wistar rats , alone and in association with different other substances . - pubmed
Emphasis is placed on unbalanced diets excluding meat , by increasing the consumption of bread and cereals , which is a universal factor for the development of visceral diseases . - pubmed
These studies will be helpful in the diagnosis as well as follow up of patients with cardiac amyloidosis . - pubmed
OBJECTIVE : To determine the implications of the presence of hyperglycemia after a cardiac surgical procedure in patients with no history of diabetes mellitus ( DM ) . - pubmed
RESULTS : Of the 50 patients , 32 ( 64 % ) were found to have persistent glucose dysregulation . - pubmed
Preoperative FPG levels correlated better with 2 - hour OGTT results than did the 6 - week postoperative FPG values , but both were insensitive markers for diagnosing type 2 DM in these patients . - pubmed
Our data support the need for performing a postoperative OGTT in patients with no known history of DM but the presence of hyperglycemia after a cardiac operation . - pubmed
Eight patients sustained a combination of clival epidural hematoma , traumatic sixth cranial nerve palsy ( 6 NP ) , and occipitocervical injury . - pubmed
Aberrant atrioventricular conduction in a patient with paroxysmal tachycardia , a short P - R interval and a normal QRS complex . - pubmed
Early globus pallidus internus stimulation in pediatric patients with generalized primary dystonia : long - term efficacy and safety . - pubmed
Except for mild dysarthria in 2 patients , no other therapy - related morbidity was observed . - pubmed
The authors found globus pallidus internus stimulation to offer a very effective and safe therapy in pediatric patients with primary dystonia . - pubmed
Challenging pacemaker implantation in a patient with acquired dextrocardia after pneumonectomy , skoliosis and complete heart block . - pubmed
The authors report the case of a pacemaker implantation in a patient with complete heart block , impaired left ventricular function , sclerosis of heart valves and radiation induced vasculopathy resulting in ostial stenosis of the right coronary artery 30 years after radiochemotherapy in childhood . - pubmed
( Rutaceae ) as potential treatment for Alzheimer disease . - pubmed
Furthermore , a better understanding of the neuropsychological impairments in drug abusing individuals could help to explain the remitting course of substance abuse disorders and to improve psychological interventions . - pubmed
The antitumor activity of sorafenib alone ( 60 mg / kg ) twice daily , cytarabine alone ( 6.25 mg / kg administered intraperitoneally ) , or sorafenib once or twice daily plus cytarabine was evaluated in NOD - SCID - IL2Rgamma ( null ) mice bearing AML xenografts . - pubmed
Physical activity coaching of patients with rheumatoid arthritis in everyday practice : a long - term follow - up . - pubmed
CHROMagar KPC appears applicable for processing carbapenem - resistant Enterobacteriaceae surveillance specimens , but its performance might possibly be suboptimal in the presence of KPC - negative ertapenem - resistant strains or for detection of KPC - producing E. - pubmed
PURPOSE : To evaluate the effects of total body irradiation ( TBI ) on the endocrine system in adults treated with hematopoietic cell transplantation ( HCT ) during childhood . - pubmed
METHODS : We studied 40 patients who underwent HCT between 1988 and 2004 , mainly for childhood cancer . - pubmed
In 23 patients , the conditioning regimen consisted of high - dose chemotherapy and TBI ( TBI+ ) . - pubmed
In the other 17 patients , who did not receive TBI ( TBI- ) , HCT was performed after high - dose chemotherapy alone . - pubmed
RESULTS : Overall , 34 % of patients in the TBI+ group showed growth hormone deficiency , compared with none of the patients in the TBI- group ( P & lt ; 0.05 ) . - pubmed
Leydig cell failure was found in 23 % of patients in the TBI+ group and in 0 % of the patients in the TBI- group . - pubmed
Also , primary hypothyroidism was more common in TBI+ ( 34 % ) than in TBI- ( 5.8 % ) patients ( P & lt ; 0.05 ) . - pubmed
CONCLUSIONS : Our data indicate that endocrine late effects after HCT are more frequent in patients who received TBI , an observation that should be considered , even if the choice of the conditioning regimen is determined by the underlying condition in most cases . - pubmed
Coupled experiment / finite element analysis on the mechanical response of porcine brain under high strain rates . - pubmed
This paper presents a coupled experimental / modeling study of the mechanical response of porcine brain under high strain rate loading conditions . - pubmed
Diabetic retinopathy ( DR ) can cause irreversible blindness and is the severest microvascular complication in the eyes of patients with diabetic mellitus ( DM ) . - pubmed
The identification of susceptibility factors contributing to development of DR is helpful for identifying predisposed patients and improving treatment efficacy . - pubmed
However , due to the high prevalence and poor outcome of visual pathway impairment , it is important to initiate multiple disciplinary co - operative study on VRT and other procedures for visual function rehabilitation to improve life quality of patients with retro - chiasmal visual pathway impairment . - pubmed
CONCLUSION : Hepatic resection for NETHM provides symptomatic benefit and is associated with favourable survival outcomes although the majority of patients invariably develop disease progression . - pubmed
Seventy - four patients with HD were evaluated for cognitive , motor , psychiatric , and functional status using a standardized battery ( Unified Huntington ' s Disease Rating Scale [ UHDRS ] and supplemental neuropsychological testing ) during a research clinic visit . - pubmed
[ Clinical study on prevention efficacy of Jianpi Huatan Fang in treating non - alcoholic fatty liver disease in children ] . - pubmed
OBJECTIVE : To verify the clinical efficacy of Jianpi Huatan Fang in treating non - alcoholic fatty liver disease in children . - pubmed
METHOD : Sixty children patients with non - alcoholic liver disease were randomly assigned to 2 groups of 30 patients each , being treated with Jianpi Huatan Fang and the Vitamin E Recipe with a span of 3 months , respectively . - pubmed
China has seen a massive resurgence of rabies cases in the last 15 years with more than 25,000 human fatalities . - pubmed
We also identified epidemiological linkages between high incidence provinces consistent with observations based on surveillance data from human rabies cases . - pubmed
METHODS AND RESULTS : Nine typically developing children ( TD ) and nine children with ASDs participated in this study ( Experiment 1 ) . - pubmed
However , there was no evidence of familiarity effect in children with ASDs . - pubmed
Screening for early detection of breast cancer : overdiagnosis versus suboptimal patient management . - pubmed
Consistent with these results , microscopic observations revealed that infection of AGS cells with H. - pubmed
pylori Deltafur mutant strain produced much less damage as compared to that produced by the wild - type H. - pubmed
The variability of the sexual incompatibility genes of Agrocybe aegerita was investigated in the homokaryotic progeny of 13 wild dikaryotic strains from five distinct European geographic origins . - pubmed
A 67 - year - old man who underwent severe chronic diarrhea had typical clinical manifestations of hyperpigmentation , hair loss , and dystrophic changes in the fingernails . - pubmed
Helicobacter pylori and anemia with pregnancy . - pubmed
SUBJECTS AND METHODS : Study was conducted in Ain Shams University hospitals on 100 pregnant women with iron - deficiency anemia ( IDA ) , including 50 cases infected with Helicobacter pylori ( H. - pubmed
CONCLUSION : Response to iron therapy in cases of iron deficiency anemia in patients without H. - pubmed
Relapse rates ( RRs ) for each patient group were compared using adjusted negative binomial regression . - pubmed
It has been estimated that in 2010 there were 4.7 million individuals aged 65 years or older with AD dementia , and it is projected that the total number of individuals with AD dementia in 2050 will be 13.8 million . - pubmed
We aimed to evaluate the prevalence of thyroid nodules , the changes in size , volume and number of nodules during pregnancy and after delivery in pregnant women . - pubmed
All patients with thyroid nodules & gt;1 cm underwent fine - needle aspiration biopsy ( FNAB ) after the last visit at the PP . - pubmed
A 17 - year - old patient with type III Gaucher disease was hospitalized for recurrent syncope . - pubmed
Gaucher disease should be kept in mind in the differential diagnosis of a young patient with extensive vascular and valvular calcification . - pubmed
Patients with symptomatic severe valvular disease must be referred for early surgery . - pubmed
Adolescents with eating disorders ( ED ) are at risk of developing osteoporosis if weight is not recovered . - pubmed
There have been no controlled trials studying the early use of percutaneous LVADs ( pLVADs ) in pericardiac arrest patients or intra - arrest as a bridge to return of spontaneous circulation . - pubmed
The ( 1,3)-beta - D - glucan ( BDG ) test was positive among 94.6 % ( 35/37 ) of candidal CRBSI patients and 9.4 % ( 10/106 ) of non - candidal CRBSI cases . - pubmed
PARTICIPANTS : Patients ( N=2130 ) enrolled between October 2008 and September 2011 and admitted for inpatient rehabilitation after an index TBI injury . - pubmed
METHODS : A cohort of 57 patients with prostate cancer scanned with ( 68 ) Ga - PSMA-11 PET / CT for radiotherapy planning was retrospectively reviewed ; 15 patients were at initial diagnosis and 42 patients at time of biochemical recurrence . - pubmed
Effect of spent turmeric on kidney glycoconjugates in streptozotocin - induced diabetic rats . - pubmed
BACKGROUND : Curcumin known to have number of medicinal use and masked the fiber containing ukonan like active polysaccharide in turmeric and its pharmacological effect will be addressed on diabetic nephropathy particularly the glycoconjugates of extracellular components viz . - pubmed
RESULTS : In the present study spent turmeric ( 10 % ) fed diabetic rats showed improved glomerular filtration rate ( 50 % ) , kidney enlargement ( 60 % ) and other glycoconjugate metabolism in kidney . - pubmed
The patients with MTBI and 40 orthopedic controls ( i.e. - pubmed
Patients with MTBI reported more post - concussion symptoms and fatigue than the controls at the beginning of recovery , but by 6 months after injury , did not differ as a group from nonhead injury trauma controls on cognition , fatigue , or mental health , and by 12 months , their level of post - concussion symptoms and quality of life was similar to that of controls . - pubmed
Investigation of mucus obtained from different fish species on the acute pain induced with scalpel incision in paw of rats . - pubmed
Atrial fibrillation is the most common arrhythmia in thyrotoxicosis , occurring in 5 - 15 % of patients over 60 years of age , whereas ventricular arrhythmia is an unusual manifestation . - pubmed
CASE REPORT : An 18 - year - old Japanese woman was admitted to our emergency department because of loss of consciousness caused by ventricular fibrillation . - pubmed
AIMS : We sought to evaluate the feasibility and efficacy of hybrid transapical closure of paravalvar mitral leaks using a new Occlutech PLD occluder in patients with heart failure and/or haemolytic anaemia . - pubmed
Clinical improvement in either heart failure or haemolysis was seen in all discharged patients . - pubmed
This strategy emphasizes the use of analogous tests and measures in both preclinical and clinical studies , while de - emphasizing the use of preclinical animal models that attempt to replicate features of the neuropsychiatric disorder through experimental manipulations . - pubmed
EXPERT OPINION : Investigating the neurobiology of key psychophysiological processes in rodents should enhance our understanding of the pathophysiology of neuropsychiatric disorders . - pubmed
No such studies are reported in the blood circulation of patients with essential hypertension . - pubmed
MATERIALS AND METHODS : We recruited 132 patients with essential hypertension and 132 normal controls from similar socio - economic - geographical background . - pubmed
INTRODUCTION : The purpose of the present study was to evaluate learning curves and short - term outcomes following laparoscopic surgery for early endometrial cancer in women of different body mass index ( BMI ) classes . - pubmed
MATERIAL AND METHODS : Data from 227 women planned for laparoscopic surgery for presumed stage I endometrial cancer were collected retrospectively from a Danish gynecologic oncology unit . - pubmed
AIMS : Stress response , in terms of activation of stress factors , is known to cause obesity and coronary heart disease such as atherosclerosis in human . - pubmed
The results indicate that TiO2 / PSi thin film irradiated with a single near - infrared wavelength of 808 nm , which is known to have the best human permeability , offers the potential of being the most successful photothermal cancer therapy agent . - pubmed
In this study , to contribute to the improvement of methods for predicting the butanol - producing ability of Clostridium beijerinckii based on starch substrate , we further investigate a simple , visualization screening method for selecting target strains from mutant library of Clostridium beijerinckii NCIMB 8052 by using trypan blue dye as an indicator in solid starch via statistical survey and validation of fermentation experiment with controlling pH. - pubmed
This study compared the outcomes of surgical treatments including bypass surgery , cutting balloon angioplasty and conventional balloon angioplasty to TA patients exhibiting supra - aortic arterial ( SAA ) . - pubmed
METHODS : This retrospective study was conducted on 42 TA patients , obtained from hospital database , who underwent surgical therapy due to SAA lesions from January 2010 to March 2015 . - pubmed
Although for many patients the mainstay of treatment for early Charcot ' s neuroarthropathy is conservative care with off - loading , early surgical correction that includes external fixation followed by definitive arthrodesis for select patients may be warranted . - pubmed
Protective Effects of Cucurbitacin B on Acute Lung Injury Induced by Sepsis in Rats . - pubmed
BACKGROUND The aim of this study was to investigate the protective effects of cucurbitacin B ( CuB ) on sepsis - induced acute lung injury ( ALI ) in rats . - pubmed
Soybean presents exciting adjunctive therapies and shows protective benefits for IC . - pubmed
Isoflavones are the main bioactive components of soybean and may be protective against heart disease . - pubmed
All patients with ischemic stroke were randomly and evenly assigned to two groups : the isoflavone group ( 80 mg day-1 , n = 100 ) and control group ( 80 mg day-1 placebo , n = 100 ) , and the whole period of the experiment was 24 weeks . - pubmed
PATIENTS AND METHODS : Patients with choroidal nevi were imaged with both OCTA and a fundus photography device . - pubmed
RESULTS : Fourteen patients with choroidal nevi were included . - pubmed
Histomorphometric study of the anterior latissimus dorsi muscle and evaluation of enzymatic markers of broilers affected with dorsal cranial myopathy . - pubmed
Dorsal cranial myopathy ( DCM ) , which affects the anterior latissimus dorsi ( ALD ) muscles of commercial broilers , is of unknown etiology , and it represents up to 6 % of the partial condemnations in Brazilian slaughterhouses . - pubmed
For each age , twelve macroscopically normal animals and twelve animals found to exhibit DCM were randomly selected for histomorphometric evaluation and analysis of serologic profiles . - pubmed
In addition , it is related to DCM lesions in fast - growing broilers with the greatest slaughter weights . - pubmed
Evaluation of the efficacy and safety of beta - d - mannuronic acid in patients with ankylosing spondylitis : A 12 - week randomized , placebo - controlled , phase I / II clinical trial . - pubmed
Patients who had AS according to the modified New York criteria , with active disease at baseline were eligible for study . - pubmed
Case presentation : An 81 - year - old Morrocan man , smoker for 40 years , presented with a 1 year history of dysphonia , dyspnea and dysphagia . - pubmed
A Missed Opportunity in Bone Health : Vitamin D and Calcium Use in Elderly Femoral Neck Fracture Patients Following Arthroplasty . - pubmed
Methods : HEALTH is a multicenter randomized trial of elderly hip fracture patients treated with hemi - arthroplasty and total hip arthroplasty . - pubmed
Sonographic diagnosis of proximal median nerve entrapment due to an arteriovenous graft in a hemodialysis patient . - pubmed
Besides the well - known palliative effects in cancer patients , cannabinoids have been shown to inhibit in vitro growth of tumor cells . - pubmed
PATIENTS AND METHODS : Material and methods : Case studies of the 38 - yerar - old patient after having operated a big aneurism of the left ICA , which was clipped . - pubmed
Conclusion : Dashansanskar churana and Khadiradi vati showed better results than chlorhexidine and were found to be superior in managing mild - to - moderate cases of chronic periodontitis . - pubmed
To investigate the phosphorylation pattern of protein on rigor mortis , goat longissimus thoracis and external intercostals were classified into two groups ( high quality and low quality ) , and meat quality was evaluated according to meat quality attributes ( Warner - Bratzler shear force , Color , pH and drip loss ) . - pubmed
This study provides a comprehensive view for the phosphorylation status of caprine muscle at rigor mortis , it also gives a better understanding of the regulation of protein phosphorylation on various biological processes that affect the final meat quality attributes . - pubmed
Materials and Methods : We design a before and after clinical trial study ( registry number : IRCT2012072610405N1 ) and investigated 40 patients with tennis elbow disease . - pubmed
All patients received 2000 pulses extracorporeal shock wave by piezoelectric device ( WOLF Company ) daily for one - week . - pubmed
Conclusion : For newly diagnosed patients with tennis elbow , extracorporeal shock wave therapy can reduce the severity of pain and improve daily activity . - pubmed
Here we report an unexpected diagnosis of a giant preperitoneal fibrolipoma detected intraoperatively during laparoscopic cholecystectomy in a 56 - year - old woman . - pubmed
[ Screening of mitochondrial DNA damage repair genes in rats with septic acute kidney injury ] . - pubmed
OBJECTIVE : : To screen genes involved in mitochondrial DNA ( mtDNA ) damage repair in rats with septic acute kidney injury ( SAKI ) . - pubmed
The SAKI mouse model was established by cecal ligation and puncture . - pubmed
Coronary blood flow volume change is negatively associated with platelet aggregability in patients with non - obstructive ischemic heart disease who have no anti - platelet agents . - pubmed
Therefore , in this study , we investigated the relationship between them in non - obstructive ischemic heart disease ( IHD ) patients . - pubmed
METHODS : Three hundred sixty - eight consecutive stable patients with suspected angina presenting non - obstructive coronary arteries ( & lt;50 % diameter ) in coronary angiography were investigated with the intracoronary acetylcholine provocation test and measured adenosine triphosphate - induced coronary flow reserve . - pubmed
Furthermore , multivariable linear regression analysis indicated that an incremental CBFV change was independently associated with PRU ( beta = 0.63 , P & lt ; 0.001 ) in non - obstructive IHD patients . - pubmed
CONCLUSIONS : In patients with non - obstructive IHD , CBFV change was significantly associated with platelet aggregability , indicating that coronary endothelial dysfunction might mediate higher platelet aggregability . - pubmed
As we learn about the various molecular alterations in this disease , additional emerging therapies can be developed to improve clinical outcomes in patients with mCRC . - pubmed
Despite a lack of direct comparative data , evidence for potential differences in effectiveness and tolerability within the dibenzazepine family has emerged from studies in which patients being treated with one dibenzazepine agent have received adjunctive treatment with another ( having achieved insufficient seizure control with the first ) or have transitioned from one dibenzazepine agent to another because of lack of effectiveness or poor tolerability . - pubmed
ESL has been shown to be effective as adjunctive therapy in patients who have previously achieved inadequate seizure control with CBZ , indicating that the use of different dibenzazepine agents in combination can provide additive effectiveness benefits , which may reflect underlying differences in their mechanisms of action . - pubmed
Aberrant Intrinsic Brain Activity in Patients with Autism Spectrum Disorder : Insights from EEG Microstates . - pubmed
The aim of this study was to examine whether the resting - state EEG microstate analysis could provide novel insights into the abnormal temporal and spatial properties of intrinsic brain activities in patients with ASD . - pubmed
To achieve this goal , EEG microstate analysis was conducted on the resting - state EEG datasets of 15 patients with ASD and 18 healthy controls from the Healthy Brain Network . - pubmed
Previous studies indicate that miR-149 could both inhibit and promote the development of human cancer depending on the tumor type . - pubmed
In the United States , outbreaks of avian influenza H5 and H7 virus infections in poultry have raised concern about the risk for infections in humans . - pubmed
We reviewed the data collected during 2014 - 2017 and found no human infections among 4,555 exposed responders who were wearing protection . - pubmed
Effects of concussion on the blood - brain barrier in humans and rodents . - pubmed
Attention is focused on concussion and traumatic brain injury in humans , with a goal of pointing out the gaps in our knowledge and how studies of rodent model systems of concussion may help in filling these gaps . - pubmed
PATIENT CONCERNS : We reported an HCC patient who developed lung metastases 1 year after HCC resection . - pubmed
DIAGNOSES : HCC patient with lung metastases , and pulmonary portal , and mediastinal lymph node metastases ( stage IVB ) . - pubmed
Fifteen months after initiation of brivanib alaninate , the patient remained in very good condition without evidence of disease progression . - pubmed
LESSONS : Brivanib alaninate alone as second - line therapy showed excellent antitumor efficacy for an HCC patient with numerous lung and lymph node metastases . - pubmed
The objective of this study was to use published information on environmental factors favorable for infection and historical climate data for the Pacific Northwest to analyze the environmental risk for Karnal bunt to occur if wheat fields in the Pacific Northwest become contaminated by T. - pubmed
METHODS AND ANALYSIS : The theory - based cluster randomised controlled trial tests an intervention comprising two components : ( 1 ) a theatre workshop for all children in years 7 and 8 , and ( 2 ) self - management workshops for children with asthma . - pubmed
Leukocyte Derived Microvesicles as Disease Progression Biomarkers in Slow Progressing Amyotrophic Lateral Sclerosis Patients . - pubmed
The lack of biomarkers in Amyotrophic Lateral Sclerosis ( ALS ) makes it difficult to determine the stage of the disease in patients and , therefore , it delays therapeutic trials . - pubmed
We investigated whether plasma derived microvesicles could be overrepresented in a group of 40 patients affected by ALS compared to 28 Alzheimer ' s Disease ( AD ) patients and 36 healthy volunteers . - pubmed
Leukocyte derived MVs ( LMVs ) compared to endothelial , platelet , erythrocyte derived MVs , were mostly present in ALS patients compared to AD patients and healthy donors . - pubmed
Our preliminary findings suggest that LMVs are upregulated in ALS patients and they can be considered possible markers of disease progression . - pubmed
In this work the thermal resistance of different yeasts strains ( seven belonging to the species Saccharomyces cerevisiae and six belonging to the species Kluyveromyces marxianus , Zygosaccharomyces bisporus , Z. - pubmed
The most resistant strain , belonging to the species S. - pubmed
Cellular immune responses in amniotic fluid of women with preterm labor and intra - amniotic infection or intra - amniotic inflammation . - pubmed
These findings provide insights into the intra - amniotic immune mechanisms underlying the human syndrome of preterm labor . - pubmed
5 children suffered from bilateral conductive hearing loss ( CHL ) , 6 children with unilateral CHL and 6 children with unilateral sensorineural hearing loss . - pubmed
Its expression was induced by SGIV infection in vitro . - pubmed
The case reported here describes a woman who underwent a total thyroidectomy for multinodular goiter and who presented an enlarged lymph node on the left side of the neck , which showed a metastasis from PTC . - pubmed
Fifteen patients were followed up for 6 to 24 months and exhibited good nasal shape , repaired alveolar cleft , improved labial shape , and closed oronasal fistula . - pubmed
One patient had local infection , which was cured by antibiotics . - pubmed
METHODS : Chart review was done for 619 patients who presented to our institution 's ED with non - febrile renal colic and received a radiological diagnosis of ureteral stone of less than 10 mm . - pubmed
We tested samples collected from camels , camel workers , and other animals in Sudan and Qatar in 2015 and 2017 for evidence of Middle East respiratory syndrome coronavirus ( MERS - CoV ) infection . - pubmed
MERS - CoV antibodies were abundant in Sudan camels , but we found no evidence of MERS - CoV infection in camel workers , other livestock , or bats . - pubmed
The NEC - protective effects of human breast milk and its constituent milk oligosaccharides ( HMOs ) on necroptosis were assessed in a " NEC - in - a - dish " model , in which mouse intestinal organoids were cultured as either " Undifferentiated " or " Differentiated " epithelium in the presence of NEC - bacteria and hypoxia . - pubmed
Strikingly , the addition of human breast milk or the HMO 2 fucosyllactose in the ex vivo system reduced necroptosis and inflammation . - pubmed
RESULTS : Routine consumption of caffeine ( odds ratio [ OR ] = 3.1 , 95 % CI : 1.23 - 6.41 , P = 0.013 ) , tobacco ( OR = 1.8 , 95 % CI : 0.67 - 3.57 , P = 0.03 ) , and alcohol ( OR = 3.6 , 95 % CI : 0.84 - 7.18 , P = 0.048 ) , and depression history ( OR = 2.8 , 95 % CI : 0.76- 5.79 , P = 0.037 ) were substantially more common among patients with bulimia . - pubmed
The area strain was the best predictor of LVEF / NYHA improvement in those patients . - pubmed
METHODS : A multicenter retrospective descriptive study was conducted in 19 dermatology departments , including all patients with PPP or ACH seen from 2014 to 2016 who received one of the studied biologics . - pubmed
The cultivated potato is susceptible and lacks resistance to bacterial wilt ( BW ) , a soil - borne disease caused by Ralstonia solanacearum . - pubmed
The limited hemocompatibility of currently used oxygenator membranes prevents long - term use of artificial lungs in patients with lung failure . - pubmed
INTRODUCTION : acrylamide is formed in food through Maillard 's reaction during thermal processing , and has been shown to be neurotoxic in humans , and a possible carcinogen . - pubmed
Preferential inhibition of adaptive immune system dynamics by glucocorticoids in patients after acute surgical trauma . - pubmed
Resting - state EEG Connectivity in Young Children with ADHD . - pubmed
METHOD : We collected EEG data in 52 medication - naive children with ADHD and in 77 typically developing controls ( 3 - 7 years ) . - pubmed
While mammals tend to repair injuries , other adult vertebrates like salamanders and fish regenerate damaged tissue . - pubmed
We assessed their impact on short- and long - term outcome in patients with colorectal liver metastases who underwent 2 - stage liver resections . - pubmed
Patients with high intramuscular fat before the second hepatectomy also showed shorter intervals from recurrence to treatment failure . - pubmed
The Sustained Attention to Response Task ( SART ) was administered to 120 children with ADHD and 123 controls on three occasions between ages 9 and 14 . - pubmed
We describe the cases of two children who presented with severe abdominal pain , non - bilious vomiting and high temperatures during the UK 's first peak of the COVID-19 pandemic . - pubmed
Clinically , the majority of patients presented with nonspecific symptoms of cough , chest pain , and dyspnea . - pubmed
Diagnostic imaging showed the presence of an anterior mediastinal mass and surgical resection of the tumor mass was performed in all the patients . - pubmed
Overweight / obesity were lower among men ( OR : 0.45 , 95 % CI : 0.340 to 0.593 , p<=0.001 ) and among patients aged > = 65 years ( OR : 0.52 , 95 % CI : 0.350 to 0.770 , p=0.001 ) ; patients who rarely ate fruits and vegetables ( OR : 0.66 , 95 % CI : 0.475 to 0.921 , p=0.014 ) but higher among patients of middle ( OR : 1.83 , 95 % CI : 1.320 to 2.550 , p<=0.001 ) and upper ( OR : 2.10 , 95 % CI : 1.450 to 2.990 , p<=0.001 ) socioeconomic status ; on dual therapy ( OR : 2.17 , 95 % CI : 1.024 to 4.604 , p=0.043 ) ; with peripheral neuropathy ( OR : 1.40 , 95 % CI : 1.039 to 1.834 , p=0.026 ) and hypertension ( OR : 1.70 , 95 % CI : 1.264 to 2.293 , p<=0.001 ) . - pubmed
Rhodiola sacra ( Prain ex Hamet ) S. H. Fu is a traditional natural plant pharmaceutical with anti - hypoxia effect and mainly distributed in Yunnan and Tibet ( China ) . - pubmed
To reveal the features of the effect of low - intensity microwave EMR / UHF on the development of adaptive metabolic and ultrastructural changes in the liver and blood of rats at an early stage of MS development . - pubmed
The derivative toxins purified from cultures of proteolytic strains of Clostridium botulinum types A and F were found to have been only partially nicked but were fully activated . - pubmed
Macrophage function in tumor - bearing mice : tumoricidal and chemotactic responses of macrophages activated by infection with Mycobacterium bovis , strain BCG . - pubmed
Thirty - one patients who had undergone a bilateral tympanic neurectomy ( sectioning of both Jacobson 's nerve and the chorda tympani ) for sialorrhea are evaluated after two years ( ranging from 24 - -45 months ) . - pubmed
Effect of pelleted feed on the incidence of gizzard erosion and black vomit in broilers . - pubmed
We evaluated the effect of breathing 100 ppm of carbon monoxide versus compressed , purified air for 1 hour on exercise performance in 10 patients with chronic obstructive pulmonary disease in a double - blind , randomized , crossover study . - pubmed
Breathing 100 ppm of carbon monoxide for 1 hour caused a significant reduction in exercise performance in patients with chronic obstructive pulmonary disease . - pubmed
Six months after surgery the patient was well and no further haemorrhage had occured . - pubmed
Ten patients with tubal infertility without antisperm antibodies or endometriosis served as controls . - pubmed
A retrospective review was made of roentgenograms from 30 patients with idiopathic osteoarthrosis of the hip . - pubmed
Natural killer ( NK ) cell activity was measured in nine patients with different solid tumors treated with flavone acetic acid ( FAA ) . - pubmed
This study investigates the quality of life of patients on alternative therapies for end - stage renal disease . - pubmed
Different effects of epoprostenol on ischemia - induced ventricular arrhythmias in dogs . - pubmed
In 60 randomized dogs the effects of epoprostenol infusion ( 100 ng / kg / min ) on ischemia - induced premature ventricular contractions ( PVCs ) , ventricular tachycardia ( VT ) , ventricular flutters and ventricular fibrillation were studied . - pubmed
The circumflex coronary artery occlusion canine model of sudden death was used . - pubmed
The results demonstrate different effects of epoprostenol on ischemia - induced ventricular arrhythmias : 1 ) both postischemic ( 7 of 30 vs 15 of 30 , p = 0.0298 ) and postreperfusion ( 5 of 23 vs 8 of 15 , p = 0.0492 ) ventricular fibrillations were prevented in epoprostenol dogs with an improvement of the global survival rate ( 18 of 30 vs 7 of 30 , p = 0.0019 ) as compared to controls ; 2 ) in epoprostenol treated dogs a significantly increased incidence of non lethal arrhythmias - including ventricular flutters that occurred in 12 of 30 dogs vs 4 of 30 in controls ( p = 0.0195)--was observed ; 3 ) a positive correlation between the percent diastolic pressure fall 10 min after the start of epoprostenol infusion and the number of non lethal arrhythmias was noted . - pubmed
Thus , the antifibrillatory and antiarrhythmic effects of epoprostenol after circumflex coronary artery occlusion and reperfusion in dogs seem independent from one another . - pubmed
The incidence of nephrotoxicity in patients receiving vancomycin alone or in combination with an aminoglycoside was prospectively evaluated . - pubmed
Eight patients ( 5 % ) receiving vancomycin alone , 14 patients ( 22 % ) receiving vancomycin with an aminoglycoside , and 11 patients ( 11 % ) receiving gentamicin alone were found to have nephrotoxicity . - pubmed
Factors found to be associated with increased risk of nephrotoxicity in patients receiving vancomycin were concurrent therapy with an aminoglycoside , length of treatment with vancomycin ( greater than 21 days ) , and vancomycin trough serum concentration ( greater than 10 mg / l ) . - pubmed
Twenty - three of 1006 ( 2.3 % ) uveal melanoma patients treated with proton beam therapy at the Harvard Cyclotron Laboratory between July 1975 and December 31 , 1986 received additional treatment for documented ( 15 patients ) or suspected ( eight patients ) tumor growth in the irradiated eye . - pubmed
Documented growth occurred in nine of 665 ( 1.4 % ) patients with small and intermediate size tumors , at times after treatment ranging from 6 to 48 months ( median 16 months ) , and in three of 341 ( .9 % ) patients with large tumors at 7 , 11 , and 12 months after treatment . - pubmed
Melanoma growing totally outside the treated volume was also documented in three additional patients at 7 , 9 , and 45 months ; two of these were thought to be " ring melanomas " . - pubmed
Eight patients had the treated eye removed elsewhere for suspected tumor growth . - pubmed
Based on these data , it appears that a dose of 70 CGE in five fractions is associated with very high rates of local control in human uveal melanoma . - pubmed
Gastrospirillum hominis infection of the stomach . - pubmed
Mutagenicity profiles of newer amsacrine analogues with activity against solid tumours : comparison of microbial and mammalian systems . - pubmed
The objective of this study was to evaluate the effect of gland cottonseed dietary fiber ( CSDF ) containing 86 % dietary fiber ( mainly cellulose ) on serum glucose levels in diabetic rats and in non - insulin - dependent diabetes mellitus ( NIDDM ) patients . - pubmed
A diet containing 15 % CSDF given to streptozotocin - induced diabetic rats for 30 d tended to reduce the postprandial plasma glucose level curve . - pubmed
Twelve NIDDM subjects were given a meal tolerance test ( MTT ) with or without CSDF before and after daily supplementation of CSDF ( 16.5 g ) in pita twice a day for a month . - pubmed
Low plasma lipid levels and increased cholesterol synthesis after partial ileal bypass plus lovastatin in hypercholesterolemic rabbits . - pubmed
For 14 weeks , 32 New Zealand White rabbits received a C - free , alfalfa - free , natural - ingredients diet previously shown to induce hypercholesterolemia . - pubmed
[ Hemorrhagic proctitis in male homosexuals caused by Chlamydia trachomatis ] . - pubmed
Viral - related RNA in Hodgkins ' disease and other human lymphomas . - pubmed
Molecular hybridization with radioactively labeled DNA complementary to the RNA of the Rauscher leukemia virus was used to probe for homologous RNA in human lymphomas . - pubmed
22 of 32 specimens contained RNA possessing homology to the RNA of the mouse leukemia virus , but not to that of the unrelated viruses causing mammary tumors in mice or myeloblastosis in chickens . - pubmed
It appears that human lymphomas contain RNA sequences homologous to those found in a viral agent known to cause leukemia and lymphomas in an experimental animal . - pubmed
The fact that human leukemias and sarcomas also contain this type of RNA further emphasizes a remarkable similarity between the corresponding neoplasias of murine and human origin . - pubmed
A case of megaloblastic anemia in the gibbon ( Hylobates foolock ) . - pubmed
[ On the therapy of peripheral circulatory disorders with the new angioactivator Tebonin of plant origin ] . - pubmed
Transient aplastic crisis in children with congenital hemolytic anemias has been linked epidemiologically to infection with a serum parvovirus - like virus ( SPLV ) . - pubmed
The case histories of 519 patients with peripheral neuropathy on whom sural nerve biopsy had been performed were reviewed . - pubmed
In 67 patients ( 50 males , 17 females ) ( 13 % ) who had symptoms of a symmetrical polyneuropathy for more than one year , the cause remained undiagnosed in spite of intensive investigation . - pubmed
Patients with inflammatory neuropathy were not included , but represented 17 % of the whole series . - pubmed
The clinical features in 43 patients were those of a mixed motor and sensory neuropathy , in 17 patients a predominantly sensory neuropathy and in 7 patients a predominantly motor neuropathy . - pubmed
A possible aetiological factor was found in 17 of the 47 patients ( 36 % ) and included malignancy , alcoholism , and benign paraproteinaemia . - pubmed
It is concluded that with intensive investigation the cause of chronic polyneuropathy of duration greater than one year remains undetermined in only about 13 % of patients and that continued follow - up is worthwhile since a diagnosis may be established on re - examination . - pubmed
Male cats that were fed the EFA - deficient diet for approximately 2 years exhibited extensive degeneration of the testes , and the fatty acid composition of testes changed in a manner consistent with EFA deficiency . - pubmed
The regimen resulted in complete azoospermia or severe oligozoospermia in all the animals within 75 days of treatment accompanied with decreased motility , vitality and increased sperm abnormalities . - pubmed
Upper urinary tract deterioration in patients with myelodysplasia and detrusor hypertonia : a followup study . - pubmed
We report on 6 patients with myelodysplasia who had undergone previously urodynamic evaluation that demonstrated detrusor hypertonia . - pubmed
Subsequently , upper urinary tract deterioration and/or vesicoureteral reflux developed in all patients and persisting detrusor hypertonia was demonstrated on followup urodynamic testing . - pubmed
Our experience indicates that detrusor hypertonia can lead to ureteral complications in patients with previously radiographically normal upper urinary tracts . - pubmed
OBJECTIVES : To examine the relationship between maternal HIV infection , placental malaria infection , and infant mortality as a first step in investigating the possibility of increased vertical transmission of HIV due to placental malaria infection . - pubmed
If confirmed , malaria chemoprophylaxis during pregnancy could decrease the impact of transmission of HIV from mother to infant . - pubmed
Although the newest compounds exhibit good activity against Streptococcus pneumoniae and intracellular pathogens in animal models , the role of quinolones as first line therapy in community - acquired pneumonia is still debatable and may be modified according to clinical presentation and the rate of resistance of pneumococci to beta - lactams and macrolides . - pubmed
Intra - arterial infusion chemotherapy via an implantable port catheter has been applied in 16 patients with locally recurrent breast cancer . - pubmed
Murine retrovirus - induced depletion of T cells is mediated through activation - induced death by apoptosis . - pubmed
Here we show for the first time that a murine retrovirus which also induces immunodeficiency can cause apoptotic T - cell death . - pubmed
Relationships between plasma levels of catecholamines and neuropeptides and the survival time in patients with congestive heart failure . - pubmed
OBJECTIVES : To evaluate the importance of various variables reflecting neuroendocrine activation in relation to prognosis in patients with congestive heart failure ( CHF ) . - pubmed
SUBJECTS : Thirty - one patients with CHF due to ischaemic heart disease . - pubmed
One hundred twenty pediatric patients with acute watery diarrhea ( 60 in each group ) were studied , but only 116 patients were included in the final analysis . - pubmed
We describe two children with deficiency of short - chain L-3 - hydroxyacyl - CoA dehydrogenase , a new disorder of the mitochondrial beta - oxidation of straight - chain fatty acids . - pubmed
The patients presented with fasting - induced vomiting , and ketosis and low blood glucose , features typical of ketotic hypoglycemia were documented in one . - pubmed
A 45 - year - old man with the acute form of pyoderma gangrenosum is reported . - pubmed
Nineteen patients were considered high risk : six had previous cardiac surgery , three were on chronic dialysis , two required emergency surgery for low output syndrome , one had a chronic tracheotomy for chronic lung disease , and seven had left ventricular ejection fraction & lt ; 30 % . - pubmed
MR consisted of ring application alone in 28 patients , chordal shortening in nine , posterior leaflet transfer in six and posterior leaflet resection in four . - pubmed
PATIENTS : The study cohort comprised 30 patients who presented with a profile of suspicion for nonorganic hearing loss . - pubmed
In order to assess the impact of a control program against Triatoma infestans launched in 1988 , based on insecticide spraying of dwellings , a serological survey for chagasic infection was carried out during 1995 in three localities from San Pedro de Atacama County ( 22 degrees 55 ' South lat . - pubmed
Blood samples from 531 children and adolescents and 65 dogs were subjected to ELISA test and indirect immunofluorescent test for Chagas ' disease respectively . - pubmed
infestans is a good tool to prevent new human infections with T. - pubmed
RESULTS : A diagnosis of herpes simplex encephalitis was confirmed in 42 patients . - pubmed
Three patients ( 7 % ) had severe neurological sequelae and died after a longer interval . - pubmed
Twenty patients ( 48 % ) performed everyday activities as well as before herpes simplex encephalitis ; nine patients ( 21 % ) were living independently , but were functioning at a lower level than before the illness ; and five patients ( 12 % ) had a severe neurological deficit . - pubmed
A 37 - year - old woman with chronic renal failure developed pain in the right flank during haemodialysis followed by rapid and dramatic deepening of pigmentation . - pubmed
Lightheadedness and unsteadiness were prominent symptoms in the elderly patients . - pubmed
Since patients with surgical resection of & gt ; 3 kg remained anemic at 10 weeks , oral iron supplements could benefit this subset of patients . - pubmed
METHODS : A total of 33 HIV-1 - infected patients with and without neurological disorders were included in the study . - pubmed
Phase II study of estramustine and vinorelbine in hormone - refractory prostate carcinoma patients . - pubmed
The purpose of this study was to evaluate the antitumor activity of vinorelbine and oral estramustine phosphate in patients with metastatic , hormone - refractory prostate cancer . - pubmed
Anemia was observed in 5 patients , alopecia in 4 and nausea and vomiting was observed in 6 patients . - pubmed
Anorexia and weight loss of more than 10 % were observed in 2 patients . - pubmed
Lung transplant recipients could particularly benefit from this enhanced exposure , but not at the expense of excessive cyclosporine toxicity . - pubmed
Nine patients with cystic fibrosis ( CF ) were randomly selected independently ( 5 , Neoral ; 4 , Sandimmune ) . - pubmed
However , patients with CF required 2 to 3 times the dose of both Neoral and Sandimmune to achieve the same C0 as non - CF patients . - pubmed
Mice receiving these bone - resorbing factors became hypercalcemic by day 3 after commencing treatment and had increased bone resorption as evidenced by elevated osteoclast numbers on day 5 . - pubmed
We aim to evaluate the use of the easier performable trocar technique in draining critically ill patients with acute calculous or acalculous cholecystitis . - pubmed
PATIENTS AND METHODS : Critically ill patients with acute acalculous ( AAC ; n=29 ) or calculous cholecystitis ( ACC ; n=7 ) underwent trocar technique application of USD . - pubmed
Estrogen , the drug of choice in perimenopausal women , is generally not recommenced to breast cancer survivors . - pubmed
PATIENTS AND METHODS : Thirty women with prior breast cancer who were suffering at least two hot flashes a day entered a single institution pilot trial to evaluate paroxetine 's efficacy in reducing the frequency and severity of hot flashes . - pubmed
The most common adverse effect was somnolence , resulting in drug discontinuation in two women , and dose reduction in two women . - pubmed
One woman discontinued drug due to anxiety . - pubmed
Ablation of this gene in mice leads to death shortly after birth , and abnormalities have been found in both the peripheral and central nervous systems . - pubmed
Differential scanning calorimetry , biochemical , and biomechanical analysis of human skin from individuals with diabetes mellitus . - pubmed
HB2 antibody treatment of SCID - HSB-2 mice also led to a significant prolongation in time to leukaemia development compared with sham - treated controls with 37 % of animals in this treatment group disease - free at termination of the study . - pubmed
Desmopressin in a long - term treatment of children with primary nocturnal enuresis -- a symptomatic therapy ? - pubmed
Enrolled in the present study were 58 patients with acute glomerulonephritis , 58 with chronic glomerulonephritis and 16 controls . - pubmed
The third and fourth sounds were detected in 61 patient with glomerulonephritis . - pubmed
It is well known that the 5 - year survival rate of advanced ovarian cancer patients greatly improved after the appearance of cisplatin . - pubmed
We examined the outcome and adverse drug reactions in 102 ovarian cancer patients who underwent repeated intraperitoneal administration of cisplatin in our hospital between April 1987 and April 1999 . - pubmed
Records of 24 consecutive patients having permanent mesh placement in contaminated wounds for repair of abdominal wall hernias between 1994 and 2001 were reviewed . - pubmed
Placement of permanent mesh prostheses in clean - contaminated and contaminated operative fields can be performed with minimal wound - related morbidity and patient mortality . - pubmed
Smoke - induced lung injury in rats was assessed in terms of histopathology , gross mortality , neutrophil accumulation and as capillary leak . - pubmed
Lupus myelopathy in a child . - pubmed
BACKGROUND : Calcium absorption is generally considered to be impaired under conditions of vitamin D deficiency , but the vitamin D status that fully normalizes absorption is not known for humans . - pubmed
Does coinfection with Human Herpesvirus 6 have a protective effect for HIV-1 progression ? - pubmed
In contrast , papilloma formation in Tg . - pubmed
AIMS : The present study was initiated by a very recent histochemical observation of lipid accumulation in the renal cortex of a woman who died in a diabetic coma . - pubmed
Two older reports of lipid accumulation in the kidneys of patients who died , most likely in a state of non - regulated diabetes , supported this observation . - pubmed
Ten subjects who died in a diabetic coma , eight diabetics who died of known causes unrelated to diabetes , and seven normal control subjects without any diagnosed diabetes who died of known causes . - pubmed
Detailed analysis of cortex lipids was performed for two of the subjects who died in a diabetic coma and all diabetic controls as well as non - diabetic control subjects . - pubmed
RESULTS : All subjects who died in a diabetic coma showed vacuolar lesions staining strongly for lipid in the proximal tubules . - pubmed
Compared with normal controls , renal cortex lipid was about tripled in the two analysed diabetic coma subjects due to 60 - 100 - fold increases of triglycerides . - pubmed
Dogs with a history of Gorilla Glue ingestion should be monitored closely by their owners and a veterinary referral made if signs of gastrointestinal distress develop . - pubmed
Parenteral feeding in a patient with hypertriglyceridemia and increased liver enzyme levels . - pubmed
OBJECTIVE : To discuss nutritional support in a patient with hypertriglyceridemia and liver dysfunction . - pubmed
METHODS : We describe the hospital course of a critically ill patient with hepatic dysfunction and hypertriglyceridemia who required nutritional support , and we provide an overview of lipid metabolism . - pubmed
RESULTS : A 27 - year - old man with hepatic dysfunction and hypertriglyceridemia , who had undergone kidney transplantation 4 months previously , was admitted to the intensive - care unit with upper gastrointestinal bleeding . - pubmed
CONCLUSION : Nutritional support in patients with liver dysfunction and hypertriglyceridemia is complicated and may require temporary underfeeding because of the need to limit fat and dextrose intake . - pubmed
We treated a 26 - year - old man with a 19 - year history of Ollier ' s disease . - pubmed
This is the first report of multiple bilateral metachronous malignant transformation of multiple chondromatoses in a patient with Ollier ' s disease . - pubmed
One important objective is to prevent human cancer . - pubmed
The aim of this study was to correlate the severity of retinopathy in diabetic patients with red blood aggregation and some parameters of aggregation . - pubmed
The study was carried out on 52 patients suffering from type 2 diabetes mellitus with non - proliferative retinopathy--25 men and 27 women ( mean age 63.8 + /- 6.5 years ) and 43 healthy--20 men and 23 women ( mean age 55.5 + /- 9.6 years ) . - pubmed
The fundus appearance of patients showed non - proliferative diabetic retinopathy . - pubmed
Once - weekly fluconazole in children with tinea capitis due to Microsporum canis . - pubmed
OBJECTIVE : To systematically assess dream characteristics and daytime aggressiveness in patients with RBD and controls . - pubmed
METHODS : Forty - nine patients with polysomnographic - confirmed RBD diagnosis and 71 age- and sex - matched controls were asked to recall the most recent dreams and to complete the Aggression Questionnaire ( AQ ) . - pubmed
Forty - one patients with RBD ( 81.6 % ; 36 men , 5 women ; mean age : 67.5 + /- 7.5 years ) and 35 controls ( 49.3 % ; 30 men , 5 women ; mean age : 69.1 + /- 5.9 years ) were able to remember their dreams and a total of 98 ( RBD ) and 69 ( controls ) dreams were collected in the two groups . - pubmed
RESULTS : Patients with RBD showed a higher percentage of dream with at least one aggressive episode ( DWA ) than controls ( 66 % vs 15 % ; p & lt ; 0.00001 ) , a higher aggression / friendliness interaction ratio ( 86 % vs 44 % ; p & lt ; 0.0001 ) , and a greater frequency of animal characters ( 19 % vs 4 % ; p = 0.0001 ) . - pubmed
CONCLUSIONS : Dreams in patients with REM sleep behavior disorder were characterized by an elevated proportion of aggressive contents , despite normal levels of daytime aggressiveness . - pubmed
Quantitative EEG analysis in dexamphetamine - responsive adults with attention - deficit / hyperactivity disorder . - pubmed
Attention - deficit / hyperactivity disorder ( AD / HD ) is recognized as a disorder affecting children and adolescents and has more recently been documented to continue into adulthood in a proportion of patients . - pubmed
Numerous studies have examined the therapeutic effects of stimulant medications in children , adolescents and adults with the disorder , reporting improvements in attention , concentration , and hyperactive and impulsive behaviours . - pubmed
Several studies have also examined the effects of stimulants on the electroencephalograph ( EEG ) of children and adolescents with the disorder , but to date , there have been no studies examining the effects of stimulant medication on the EEG of adults with AD / HD . - pubmed
In the present study , we aimed to replicate previous EEG findings in adults with AD / HD relative to controls and to examine whether there was any change in this profile following treatment with dexamphetamine . - pubmed
The pre - medication results are similar to those found in previous research that compared the EEGs of adults with AD / HD and control subjects . - pubmed
Over the past decade , adenovirus ( Ad)-based vectors have been used extensively in the context of cancer gene therapy . - pubmed
Several obstacles limiting the therapeutic activity of Ad vectors have been encountered , including efficiency of tumor cell transduction and inhibition of efficacy by anti - Ad host immune responses . - pubmed
Involvement of adenosine in depression of synaptic transmission during hypercapnia in isolated spinal cord of neonatal rats . - pubmed
In the isolated spinal cord of the neonatal rat in vitro , acute hypercapnic acidosis ( 20 % CO2 , pH 6.7 ) reversibly depressed electrically evoked spinal reflex potentials . - pubmed
MATERIAL AND METHODS : Two hundred and four patients of non - traumatic myelopathy were prospectively studied in different wards of Sir Sundar Lal Hospital , Institute of Medical Sciences , Banaras Hindu University , Varanasi , from September 2002 to March2004 . - pubmed
RESULTS : Among 204 patients of non - traumatic myelopathy , 108 patients presented with paraplegia and 96 patients with quadriplegia . - pubmed
Patient - controlled analgesia in the management of postoperative pain . - pubmed
Patient - controlled analgesia ( PCA ) is a delivery system with which patients self - administer predetermined doses of analgesic medication to relieve their pain . - pubmed
These include improved pain relief , greater patient satisfaction , less sedation and fewer postoperative complications . - pubmed
Susceptibility of CCR5 - deficient mice to genital herpes simplex virus type 2 is linked to NK cell mobilization . - pubmed
Unfortunately , ACC has undergone metastatic spread in 40 % to 70 % of patients at the time of diagnosis . - pubmed
Genomes of 25 ACC clinical samples were queried on the Agilent 44 K Human Genome comparative genomic hybridization array detecting regions of chromosomal gain and loss within the tumor population . - pubmed
Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers . - pubmed
Monitoring of body weight and immune cell infiltrates in the lungs of noninfected mice indicated that PPMO treatment was not toxic at a concentration shown to be effectively antiviral in vivo . - pubmed
METHOD : Measures completed included the Children 's Depression Inventory , the Multidimensional Anxiety Scale for Children , the Child Behavior Checklist and the Disruptive Behavior Rating Scale . - pubmed
Lateral sinus thrombosis is a rare complication of middle ear diseases : in children , it is usually related to acute otitis media , but it is also found in adults with chronic otitis . - pubmed
Hypericum perforatum ( St John 's wort ) for attention - deficit / hyperactivity disorder in children and adolescents : a randomized controlled trial . - pubmed
CONTEXT : Stimulant medication can effectively treat 60 % to 70 % of youth with attention - deficit / hyperactivity disorder ( ADHD ) . - pubmed
perforatum for the treatment of ADHD in children . - pubmed
DESIGN , SETTING , AND PARTICIPANTS : Randomized , double - blind , placebo - controlled trial conducted between March 2005 and August 2006 at Bastyr University , Kenmore , Washington , among a volunteer sample of 54 children aged 6 to 17 years who met Diagnostic and Statistical Manual of Mental Disorders ( Fourth Edition ) criteria for ADHD by structured interview . - pubmed
perforatum vs 3.2 points ( 95 % CI , -5.7 to -0.8 points ) with placebo ( P = .68 ) and hyperactivity improved 1.8 points ( 95 % CI , -3.7 to 0.1 points ) with H. - pubmed
Therapeutic time window and mechanism of tetramethylpyrazine on transient focal cerebral ischemia / reperfusion injury in rats . - pubmed
Middle cerebral artery occlusion was conducted in male Sprague - Dawley rats and 20mg / kg tetramethylpyrazine was injected intraperitoneally at different time points . - pubmed
Controversy surrounds the optimal technique for fixation of displaced fractures , although locked intramedullary nailing is emerging as a preferred technique in managing displaced proximal humerus fractures in appropriately selected patients . - pubmed
OBJECTIVE : To isolate and elucidate the chemical constituents with the cytotoxicity activity from the rhizome of Actaea asiatica . - pubmed
In this investigation 830 healthy controls , 69 subjects with cognitive impairment and not dementia ( CIND ) , 53 patients with severe clinical AD and 142 patients with mild AD were investigated . - pubmed
Patients with mild clinical AD were followed up for two years and stratified according to the rate of clinical deterioration . - pubmed
Clinical outcomes after platelet transfusions in patients with thrombotic thrombocytopenic purpura . - pubmed
STUDY DESIGN AND METHODS : Published reports of PLT transfusions in patients with TTP were systematically reviewed and data from the Oklahoma TTP - HUS Registry , an inception cohort of 382 consecutive patients , 1989 through 2007 , were analyzed . - pubmed
The frequency of death was not different between the two groups ( p = 0.971 ): 8 ( 24 % ) patients who received PLT transfusions died ( thrombosis , 5 ; hemorrhage , 1 ; sepsis , 2 ) and 5 ( 24 % ) patients who did not receive PLT transfusions died ( thrombosis , 4 ; hemorrhage , 1 ) . - pubmed
CONCLUSION : Evidence for harm from PLT transfusions in patients with TTP is uncertain . - pubmed
Vandetanib versus gefitinib in patients with advanced non - small - cell lung cancer : results from a two - part , double - blind , randomized phase ii study . - pubmed
Risk factors for recurrence after Staphylococcus aureus bacteraemia . - pubmed
OBJECTIVES : We sought to identify risk factors for recurrence of Staphylococcus aureus bacteraemia ( SAB ) by auditing compliance with guidelines on its treatment in our hospital . - pubmed
Analysis of outcomes of vascularized flap reconstruction in patients with advanced mandibular osteoradionecrosis . - pubmed
SUBJECTS : Patients with end - stage radiation - induced osteoradionecrosis ( ORN ) refractory to conservative therapy with wound complications including chronic infections , fistula formation , and pathologic fracture were included . - pubmed
An elusive tumor in a man who has evidence of prostate cancer metastasis . - pubmed
Attenuation of allergy to ovomucoid in pigs by neonatal treatment with heat - killed Escherichia coli or E. - pubmed
To assess induction of allergy , pigs were fed egg white in yoghurt and assigned scores for allergic signs . - pubmed
Significantly fewer pigs developed allergy and passive cutaneous anaphylaxis in E. - pubmed
Seventy nonobese patients with CHC ( Group 1 ) confirmed by the presence of serum hepatitis C virus ( HCV)-RNA and 20 healthy volunteers ( Group 2 ) , similar in age and BMI with normal fasting glucose and lipid profile were included . - pubmed
The lowest levels were found in patients with the most advanced inflammation : grades 3 - 4 - 46.8 + /- 17.1 , grade 2 - 52.6 + /- 18.4 and grade 1 - 75.2 + /- 27.6 ng / mL ; P = 0.017 . - pubmed
Regarding " Prediction of 30 - day mortality after endovascular repair or open surgery in patients with ruptured abdominal aortic aneurysms " . - pubmed
BACKGROUND AND PURPOSE : Low - dose lipopolysaccharide ( LPS ) preconditioning provides neonatal rats long - term neuroprotection against hypoxic ischemia ( HI ) . - pubmed
CASE PRESENTATION : A 73 - year - old Caucasian woman presented to our department with sudden onset , severe , left - upper abdominal pain . - pubmed
Postictal delta can be lateralized in 60 % of patients with TLE and is concordant with the side of seizure onset in most patients . - pubmed
Accurate localization of the seizure onset in these patients is required for successful surgical management . - pubmed
Midterm results of arterial switch operation in older patients with severe pulmonary hypertension . - pubmed
BACKGROUND : It is widely accepted that patients older than 6 months with dextrotransposition of the great arteries and nonrestrictive ventricular septal defect or Taussig - Bing anomaly and severe pulmonary hypertension usually are not candidates for an arterial switch operation or even repair . - pubmed
METHODS : The records of 86 patients older than 6 months with dextrotransposition of the great arteries and nonrestrictive ventricular septal defect or Taussig - Bing anomaly and severe pulmonary hypertension undergoing the arterial switch operation at our institution from 2000 to 2008 were reviewed retrospectively . - pubmed
CONCLUSIONS : Midterm results of the arterial switch operation for patients older than 6 months with dextrotransposition of the great arteries and nonrestrictive ventricular septal defect or Taussig - Bing anomaly and severe pulmonary hypertension are excellent in the current era . - pubmed
We show for the first time that dehydration leads to an increase in cellular PtdIns5P in Arabidopsis . - pubmed
[ Clinical characteristics of hepatic veno - occlusive disease in 6 children with hematologic neoplasm treated with 6 - thioguanine ] . - pubmed
OBJECTIVE : To improve the treatment of drug related childhood hepatic veno - occlusive disease ( HVOD ) , clinical characteristics of 6 children with hematologic neoplasm from 2 hospitals of China Children 's Leukemia Group ( CCLG ) treated with 6 - thioguanine ( 6 - TG ) complicated with HVOD were analyzed . - pubmed
METHOD : All the drug related HVOD patients were treated with CCLG acute lymphoblastic leukemia ( ALL)-2008 protocol . - pubmed
The 6 HVOD patients ' clinical manifestations , laboratory finding , imageologic and pathologic data were collected and analyzed . - pubmed
All the patients recovered after being treated with hepatoprotective , jaundice - relieving and supportive therapeutics , some patients were treated with low molecular weight heparin . - pubmed
Mortality associated with atrial fibrillation in patients with myocardial infarction : a systematic review and meta - analysis . - pubmed
BACKGROUND : Atrial fibrillation ( AF ) is a common finding in patients with myocardial infarction ( MI ) . - pubmed
Drugs administered individually or as a mixtures of all three after TBI significantly increased mouse survival ( p = 0.0234 , 0.0009 , 0.0052 , and 0.0167 , respectively ) . - pubmed
CONCLUSION : Mitochondrial targeting of small molecule radiation mitigators decreases irradiation - induced cell death in vitro and prolongs survival of lethally irradiated mice . - pubmed
Two patients experienced hematoma and one patient experienced late infection at four months postoperatively . - pubmed
These data provide surgeons with a less invasive treatment option for patients with early breast cancer , even when they have undergone prior breast augmentation through a transaxillary approach . - pubmed
METHODS : This prospective study included adult patients with progressive LGG that was confirmed by magnetic resonance imaging ( MRI ) . - pubmed
RESULTS : A total of 21 LGGs from 31 patients were included in the study , and followed for at least n=14 months during treatment . - pubmed
A total of 18 ( 86 % ) patients experienced a decrease in tumour volume with a greater decrease of metabolic ratios . - pubmed
The evolutions over time of metabolic ratios , mean(Cho / Cr)(n ) and mean(Cho / NAA)(n ) , were significantly correlated with the evolution of the mean relative decrease of tumour volume , mean(DeltaV(n)/V(o ) ) , according to a linear regression ( P<0.001 ) in the ' response / no relapse ' patient group , and with the evolution of the mean tumour volume ( meanV(n ) ) , according to an exponential regression ( P<0.001 ) in the ' response / relapse ' patient group . - pubmed
Incidence and diagnosis of heparin - induced thrombocytopenia ( HIT ) in patients with traumatic injuries treated with unfractioned or low - molecular - weight heparin : a literature review . - pubmed
CONCLUSION : The incidence of HIT in trauma patients who receive LMWH thromboprophylaxis appears to be low ( 0.36 % ) . - pubmed
Incidence of HIT in patients with isolated lower leg injuries receiving LMWH seems very low . - pubmed
Monitoring of platelet count could be considered in hospitalised patients with a high risk for development of HIT . - pubmed
Using bacterial artificial chromosome technology , each of these mutations was individually transferred into the genome of a reference strain . - pubmed
ewingii have been thought to cause ehrlichiosis in humans in the United States . - pubmed
RESULTS : On testing , four cases of ehrlichiosis in Minnesota or Wisconsin were found not to be from E. - pubmed
A total of 108 rats were randomly distributed into three groups : sham - operated group ( n = 12 ) , middle cerebral artery occlusion ( MCAO ) group ( n = 48 ) , MCAO+treadmill exercise group ( n = 48 ) . - pubmed
Behavioral testing indicated that treadmill exercise could significantly improve neurologic deficits of rats with cerebral ischemia at day 14 and 28 after MCAO ( n = 12 , P<0.05 and P<0.01 ) , but there was no significant difference at day 4 and 7 . - pubmed
Administered as monotherapy or in combination with other antihyperglycemic agents , they represented an effective option for achieving or maintaining good glycemic control in patients with T2DM . - pubmed
Seroma was seen in 8.6 % ( 5 ) of patients . - pubmed
CONCLUSIONS : EE 20 mcg / drsp 3 mg in a 21/7 - day regimen provides comparable ovarian suppression in Japanese and Caucasian women , with normal ovarian function resuming shortly after treatment end in both populations . - pubmed
BACKGROUND & amp ; AIMS : Parenteral nutrition is widely used in critically ill patients receiving nutritional support . - pubmed
Statistical analysis of data , grouped according to preparation method , compared differences in both observed bloodstream infection rates and adjusted rates , using logistic regression to examine the impact of hospital and patient baseline characteristics . - pubmed
Vegetal polymer in repair of defects of the orbital floor : an experimental study in rabbits . - pubmed
We extracted the following information : author names and publication year ; clinical outcome ( number of deaths and Glasgow outcome scales ) ; perioperative data ( number of moderate or severe intraoperative brain swelling occurrences , hypertensive episodes , ruptured or leaking aneurysms , volume of blood loss during surgery , duration of temporary clipping , and number of patients who received protective drugs , who required rewarming and who were intubated ) ; number of adverse events ( cerebral infarctions , brain swelling , myocardial ischaemia or infarction , congestive heart failure , meningitis or ventriculitis and pneumonia ) . - pubmed
RESULTS : The number of patients requiring rewarming in the mild hypothermia group was significantly greater than in the normothermia group ( odds ratio , 33.89 ; 95 % confidence intervals , 3.61 - 318.36 ) . - pubmed
PATIENTS : Patients undergoing total hip replacement , total knee replacement , or hip fracture surgery who received prophylaxis with a LMWH or another anticoagulant . - pubmed
Patients with idiopathic passive faecal incontinence were selected for trans - submucosal injection of Permacol ( ) after assessment by anorectal physiology and endoanal ultrasonography . - pubmed
Compounds 1 - 7 were tested in vitro for their cytotoxic effects on five cell lines including human gastric adenocarcinoma cell line ( BGC823 ) , human hepatocarcinoma cell line ( HepG2 ) , human melanoma cell line ( A375 ) , human oral squamous carcinoma cell line ( KB ) , and ghost cell line ( Ghost - R5X4 ) . - pubmed
Cost - effectiveness of adding - on new antiepileptic drugs to conventional regimens in controlling intractable seizures in children . - pubmed
0.06 % of children around the world are estimated to suffer from epilepsy and its consequences . - pubmed
The aim of the present study has been to evaluate the cost - effectiveness of these drugs in the treatment of intractable seizures in children . - pubmed
With the advent of deep sequencing , efforts have been put forth to profile the miRNome in a number of human malignancies . - pubmed
We describe a new technique to prevent spillage of cyst fluid in patients undergoing surgery for cystic ovarian tumors . - pubmed
DESIGN AND METHODS : Thirteen postpartum women ( mean + - SD : 25.6 + - 4.5 years , 72.0 + - 11.9 kg ) provided fore- and hindmilk samples 4 - 5 weeks after delivery and underwent measurements of body weight and composition by Dual X - ray Absorptiometry . - pubmed
By delivering small - diameter nociceptive - specific laser pulses to human volunteers , we discovered that ( 1 ) the spatial acuity for pain is higher on the fingertips than on proximal skin regions such as the hand dorsum , and ( 2 ) this distal - proximal gradient for pain is comparable to that for touch . - pubmed
Identification of novel exons and transcripts by comprehensive RNA - Seq of horn cancer transcriptome in Bos indicus . - pubmed
Horn cancer ( HC ) is a widely prevalent cancer amongst Bos indicus cattle and frequently associated with economic losses due to reduction in draught and milk production capacity . - pubmed
A 74 - year - old male patient with a newly diagnosed prostate cancer had whole - body bone scintigraphy for staging . - pubmed
Many people infected with the human immunodeficiency virus type-1 ( HIV ) exhibit mild or severe neurological problems , termed HIV - associated neurocognitive disorder ( HAND ) , even when receiving antiretroviral therapy . - pubmed
Thus , novel adjunctive therapies must be developed to overcome the neurotoxic effect of HIV . - pubmed
HIV appears to impair neuronal plasticity , which refers to the innate ability of the CNS respond to injury and promote recovery of function . - pubmed
OBJECTIVE : To identify risk factors for developing a first febrile status epilepticus ( FSE ) among children with a first febrile seizure ( FS ) . - pubmed
STUDY DESIGN : Cases were children with a first FS that was FSE drawn from the Consequences of Prolonged Febrile Seizures in Childhood and Columbia cohorts . - pubmed
MATERIALS AND METHODS : Volumetric scans of 247 individuals exposed to tobacco with different functional status ( normal to severe COPD ) , were retrospectively and independently evaluated by 2 chest radiologists , with a consensual reading additionally with a third reader in disagreement cases . - pubmed
OBJECTIVES : There is evidence that androgens are breast protective and that testosterone therapy treats many symptoms of hormone deficiency in both pre and postmenopausal patients . - pubmed
However , unlike estrogen and progestins , there is a paucity of data regarding the incidence of breast cancer in women treated with testosterone therapy . - pubmed
This study was designed to investigate the incidence of breast cancer in women treated with subcutaneous testosterone therapy in the absence of systemic estrogen therapy . - pubmed
Breast cancer incidence was compared with that of historical controls reported in the literature , age specific Surveillance Epidemiology and End Results ( SEER ) incidence rates , and a representative , similar age group of our patients used as a ' control ' group . - pubmed
Differences in proliferative capacity of primary human acute myelogenous leukaemia cells are associated with altered gene expression profiles and can be used for subclassification of patients . - pubmed
OBJECTIVES : Proliferative capacity of acute myelogenous leukaemia ( AML ) blasts is important for leukaemogenesis , and we have investigated whether proliferative capacity of primary human AML cells could be used for subclassification of patients . - pubmed
CONCLUSIONS : In vitro proliferative capacity of primary human AML cells was considerably variable between patients and could be used to identify biologically distinct patient subsets . - pubmed
During a median follow - up of 41 months , no patient developed exocrine insufficiency . - pubmed
Three elderly patients developed non - insulin - dependent diabetes mellitus . - pubmed
One patient with VIPoma developed recurrence and liver metastasis . - pubmed
Surveillance of intra - abdominal pressure and intestinal barrier function in a rat model of acute necrotizing pancreatitis and its potential early therapeutic window . - pubmed
Methanolic extracts of both Pedicularis sibthorpii and Pedicularis wilhelmsiana were found to have antibacterial activity especially against gram positive strains of S. - pubmed
Clinical data , aneurysm characteristics , treatment methods , and the incidence and causes of re - exploration of the craniotomy were analyzed for these 26 patients . - pubmed
RESULTS : Several causes of re - exploration were identified : compromised distal blood flow ( eight patients , 0.47 % ) , hemorrhagic venous infarction ( four patients , 0.23 % ) , brain retraction injury ( three patients , 0.17 % ) , newly identified aneurysms ( three patients , 0.17 % ) , bleeding from an incompletely clipped aneurysm ( two patients , 0.12 % ) , epidural hematoma ( two patients , 0.12 % ) , failed aneurysm clipping ( two patients , 0.12 % ) and other causes ( two patients , 0.12 % ) . - pubmed
However , this dosing regimen resulted in average trough concentrations & gt;20 mg / L. In the peritoneal cavity , no regimen yielded PTA & gt;=90 % for MIC values & gt;=0.5 mg / L. CONCLUSIONS : Although expert guidelines suggest iv vancomycin may be an acceptable empirical therapy for patients on APD with infection , these analyses indicate that iv vancomycin may not be effective for peritonitis but may be a viable option for non - peritoneal infections with MIC values & lt;=1 mg / L. - pubmed
However , the molecular mechanisms underlying compensatory liver regeneration in mice after APAP - induced liver injury are not completely understood . - pubmed
We found that mice exhibited massive hepatic toxicity during the first 12 hours after 400 mg / kg APAP treatment , but responsive liver recovery occurred beyond 24 hours as demonstrated by histopathological and biochemical assessments . - pubmed
[ Soluble apoptosis markers in obese patients with food intolerance ] . - pubmed
For the soluble apoptosis markers study 151 patients with obesity ( 92 women and 59 men ) aged between 18 and 63 years were examined . - pubmed
Generally food intolerance was identified in 36.4 % of obese patients . - pubmed
Obese patients with food intolerance received standard version of hypocaloric diet with the exception of specific food allergens . - pubmed
Factors associated with the seroprevalence of leishmaniasis in dogs living around Atlantic Forest fragments . - pubmed
The results showed that different risk factors than those found in urban areas may drive the prevalence of canine leishmaniasis in farm / forest interfaces , and that humans and wildlife risk infection in these areas . - pubmed
Noncontact , low - frequency ultrasound therapy enhances neovascularization and wound healing in diabetic mice . - pubmed
BACKGROUND : Chronic wounds are a major source of morbidity for patients and represent a significant health burden . - pubmed
Ultrasound appears to be an effective modality for the treatment of chronic wounds in humans . - pubmed
CONCLUSION : Noncontact , low - frequency ultrasound treatment improves neovascularization and wound closure rates in excisional wounds for diabetic mice , likely because of the stimulated release of angiogenic factors . - pubmed
Characterization of circulating microRNA expression in patients with a ventricular septal defect . - pubmed
METHODS : MiRNA microarray analysis and reverse transcription - polymerase chain reaction ( RT - PCR ) were employed to determine the miRNA expression profile from 3 patients with VSD and 3 VSD - free controls . - pubmed
miRNAs that were generally consensus across the three databases were selected and then independently validated using real time PCR in plasma samples from 20 VSD patients and 15 VSD - free controls . - pubmed
RESULTS : 36 differentially expressed miRNAs were found in the patients with VSD and the VSD - free controls . - pubmed
CONCLUSION : We report for the first time the circulating miRNA profile for patients with VSD and showed that 7 miRNAs were downregulated and 1 upregulated when matched to VSD - free controls . - pubmed
Preclinical safety evaluation of a recombinant AAV8 vector for X - linked retinoschisis after intravitreal administration in rabbits . - pubmed
In conclusion , intravitreal administration of AAV8 - scRS / IRBPhRS into the rabbit eye produces a mild and transient intraocular inflammation that resolves , at a 2e(10 ) vg / eye dose , within 3 months , and does not cause irreversible tissue damages . - pubmed
These data support the initiation of a clinical trial of intravitreal administration of AAV8 - scRS / IRBPhRS in XLRS patients . - pubmed
We report here the complete genome sequence of a novel reassortant H4N2 avian influenza virus strain , A / duck / Guangxi / 125D17 / 2012 ( H4N2 ) ( GX125D17 ) , isolated from a duck in Guangxi Province , China in 2012 . - pubmed
Information about the complete genome sequence of the GX125D17 virus strain will be useful for epidemiological studies . - pubmed
The acquisition of genomic instability is a triggering factor in cancer development , and common fragile sites ( CFS ) are the preferential target of chromosomal instability under conditions of replicative stress in the human genome . - pubmed
TRALI : human neutrophil antigens and antibodies . - pubmed
A 74 - year - old woman was admitted to our department on day two of a bilateral PICA thrombosis with developing cerebellar infarction . - pubmed
Hepatitis B virus ( HBV ) remains a major human pathogen , with over 240 million individuals suffering from chronic HBV infections . - pubmed
Using lentiviral transduction of a bacterial Cas9 gene and single guide RNAs ( sgRNAs ) specific for HBV , we observed effective inhibition of HBV DNA production in in vitro models of both chronic and de novo HBV infection . - pubmed
METHODS : Fifty patients with myopia who underwent LASIK ( 100 eyes ) were divided into two equal groups . - pubmed
METHODS : EPSN was measured in 92 sera collected from 46 pregnant women with birth at term and 40 sera from 20 pregnant women with preterm birth . - pubmed
Patients with SPB showed a considerable increase of EPSN in the second trimester compared with patients with birth at term ( 7.30 + -1.53 vs. 6.16 + -0.23 , P=0.043 ) . - pubmed
After an in vitro model of IR was established by treating human liver cancer cells ( HepG2 cells ) with palmitic acid , the cells were then treated with various concentrations of QJJ . - pubmed
CONCLUSION : The treatment of warm needling combined with element calcium on postmenopausal osteoporosis is significant , which is likely to be achieved by reducing the bone metabolism of postmenopausal patients . - pubmed
Though both the low concentration of spinosad and the ultra - low - volume application rate of GF-120 are supposed to have a low acute toxicity in honey bee foragers , to our knowledge such claims have not been explicitly proven . - pubmed
BACKGROUND : Health promoting schools focus on , amongst other things , preventing leading causes of death such as Sexually Transmitted Infections ( STI 's ) , Human Immune Deficiency Virus ( HIV ) and Acquired Immunodeficiency Syndrome ( AIDS ) , a sedentary lifestyle and creating conditions that are conducive to health through health education . - pubmed
Echinacea Formula ( Echinaforce Hotdrink ): Effects of a Proprietary Echinacea Formula Compared With Oseltamivir in the Early Treatment of Influenza . - pubmed
Traditionally , in oriental medicine , apricot seed ( Semen Armeniacae amarum ) is used to treat skin diseases . - pubmed
PATIENTS : 108 patients with unstable pelvic injuries were operated by the orthopedic department at the Soroka University Medical Center between the years 1999 - 2010 . - pubmed
Antibacterial effect of N - acetylcysteine on common canine otitis externa isolates . - pubmed
BACKGROUND : N - Acetylcysteine ( NAC ) has the potential to be a useful therapeutic agent for the treatment of otitis externa due to its antimicrobial and mucolytic properties , as well as its ability to disrupt bacterial biofilm . - pubmed
ANIMALS : Twenty two isolates from canine clinical cases of otitis externa were identified and tested , including five Staphylococcus pseudintermedius , six Pseudomonas aeruginosa , five Corynebacterium spp . - pubmed
CONCLUSIONS AND CLINICAL RELEVANCE : N - Acetylcysteine inhibits clinically relevant and drug resistant bacteria in vitro , and has potential for use as a novel agent for treatment of otitis externa . - pubmed
METHODS : A retrospective analysis was performed of 98 patients with TBC who underwent BDC of 2510 patients with traumatic brain injury . - pubmed
For the rich mobilome of a hospital Klebsiella pneumoniae strain , circularization junctions ( CJs ) were detected for six GIs and seven IS types . - pubmed
Forty diabetic patients with critical coronary stenosis were subjected to elective coronary scaffold implantation in Al - Najaf Center for Cardiac Surgery and Trans - Catheter Therapy , Najaf , Iraq , between January and July 2015 . - pubmed
CONCLUSION : Our study concluded that trimetazidine minimizes the acute inflammatory response occurred due to systemic release of inflammatory markers into blood in diabetic patients undergoing elective Novolimus bioresorbable coronary scaffold implementation . - pubmed
Antimicrobial - resistant pneumococcal strains have been detected worldwide since the 1960s . - pubmed
In Brazil , the first penicillin - nonsusceptible pneumococci ( PNSP ) were reported in the 1980s , and their emergence and dissemination have been mainly attributed to serogroup 9 and serotype 14 strains , especially those highly related to recognized international clones . - pubmed
The earliest PNSP strains detected in this study belonged to serotype 9N / ST66 and were single locus variants of the international clone Tennessee14 - 18 ST67 ( CC66 ) . - pubmed
Experimental Design : Early - passage human malignant mesothelioma cell lines NCI - Meso16 , NCI - Meso19 , NCI - Meso21 , and NCI - Meso29 were evaluated for sensitivity to RG7787 or nab - paclitaxel alone or in combination . - pubmed
In addition , the antitumor activity of RG7787 plus nab - paclitaxel was evaluated using NCI - Meso16 , NCI - Meso21 , and NCI - Meso29 tumor xenografts in immunodeficient mice . - pubmed
These results indicate that this combination could be useful for treating patients with mesothelioma . - pubmed
INTRODUCTION : Renal cell carcinoma ( RCC ) is the most fatal of the common urologic cancers , with approximately 35 % of patients dying within 5 years following diagnosis . - pubmed
There were no differences in the intervention effect on 90 - day mortality in patients with chronic lung disease ( test of interaction P = 0.31 ) , haematological malignancy ( P = 0.47 ) , metastatic cancer ( P = 0.51 ) , in those who had undergone surgery ( P = 0.99 ) or in patients with septic shock by the new definition ( P = 0.20 ) . - pubmed
RESULTS : The patients ' mean age was 63 + - 13 years , 81 % were male , 53 % had an ischemic cause of heart failure , and 68 % underwent LVAD implantation as destination therapy . - pubmed
CONCLUSIONS : Continuous - flow LVAD improves renal and hepatic functions in patients with advanced heart failure . - pubmed
BACKGROUND : A study was performed in adults with acute appendicitis and matched controls to assess the utility of the platelet indices and neutrophil to lymphocyte ratio , as a diagnostic adjunct . - pubmed
METHOD : Data were retrospectively collected from a complete blood count test of 155 adult patients ( 72 men and 83 women ) with histologically proven acute appendicitis upon admission , and of 50 healthy adults ( 20 men and 30 women ) . - pubmed
A single older stroke patient showed baseline ipsilateral MCAV that was lower still and devoid of any exercise response whatsoever . - pubmed
METHODS : The present prospective cross sectional study was performed on critically ill patients presented to emergency department during 6 months . - pubmed
RESULTS : 82 critically ill patients with the mean age of 53.45 + - 20.37 years were included ( 65.9 % male ) . - pubmed
The purpose of this study is to compare the two methods ' success and practicality that are applied after the fracture of the stone in the patients who applied PCNL and which enable the removal of the residual stones . - pubmed
Feeding rosemary leaves powder ameliorates rooster age - related subfertility . - pubmed
On the basis of the phenotypic and phylogenetic data , along with low dDDH and ANI values among these strains , these bacteria are assigned to the following nine novel species of the B. - pubmed
, type strain Mn5 T (= MCCC 1A00395T = KCTC 33714T = LMG 28873 T ) ; Bacillus pacificus sp . - pubmed
, type strain EB422 T (= MCCC 1A06182T = KCTC 33858 T ) ; Bacillus tropicus sp . - pubmed
, type strain N24 T (= MCCC 1A01406T = KCTC 33711T = LMG 28874 T ) ; Bacillus albus sp . - pubmed
, type strain N35 - 10 - 2 T (= MCCC 1A02146T = KCTC 33710T = LMG 28875 T ) ; Bacillus mobilis sp . - pubmed
, type strain 0711P9 - 1 T (= MCCC 1A05942T = KCTC 33717T = LMG 28877 T ) ; Bacillus luti sp . - pubmed
, type strain TD41 T (= MCCC 1A00359T = KCTC 33716T = LMG 28872 T ) ; Bacillus proteolyticus sp . - pubmed
, type strain TD42 T (= MCCC 1A00365T = KCTC 33715T = LMG 28870 T ) ; Bacillus nitratireducens sp . - pubmed
, type strain 4049 T (= MCCC 1A00732T = KCTC 33713T = LMG 28871 T ) ; and Bacillus paramycoides sp . - pubmed
Test formula was a hypoallergenic , nutritionally complete AAF including a prebiotic blend of fructo - oligosaccharides and the probiotic strain Bifidobacterium breve M-16V. - pubmed
Methods : Forty patients with metastatic castration - resistant prostate cancer were selected for treatment with three 100 kBq / kg cycles of 225Ac - PSMA-617 at 2 - mo intervals . - pubmed
Five patients discontinued treatment because of nonresponse , and 4 because of xerostomia . - pubmed
The median duration of tumor control under 225Ac - PSMA-617 last - line therapy was 9.0 mo ; 5 patients had an enduring response of more than 2 y. - pubmed
Because all patients had advanced disease , this result compares favorably with the tumor control rates associated with earlier - phase disease ; the most common preceding first- , second- , third- , and fourth - line therapies were abiraterone ( median duration 10.0 mo ) , docetaxel ( 6.5 mo ) , enzalutamide ( 6.5 mo ) , and cabazitaxel ( 6.0 mo ) , respectively . - pubmed
Swimmer - plot analysis indicates a promising duration of tumor control , especially considering the unfavorable prognostic profile of the selected advanced - stage patients . - pubmed
Xerostomia was the main reason patients discontinued therapy or refused additional administrations and was in the same dimension as nonresponse ; this finding indicates that further modifications of the treatment regimen with regard to side effects might be necessary to further enhance the therapeutic range . - pubmed
Urinary tract infection due to Fusarium oxysporum in an immunocompetent patient with chronic kidney disease . - pubmed
Fusarium oxysporum has been reported to cause keratitis , onychomycosis , skin infections , catheter associated fungemia and has not been described as a cause of urinary tract infection . - pubmed
vulgare , Apiaceae ) is an important plant currently used in folk medicine to treat various diseases including infections and inflammatory conditions . - pubmed
OBJECTIVE : The aim of our study was to investigate the potential differential effect of hyperglycaemia and hyperinsulinaemia induced by glucose infusion alone and in combination with leucine consumption on endothelial function in healthy individuals . - pubmed
CONCLUSIONS : Acute hyperglycaemia impairs endothelial function in healthy male individuals . - pubmed
This study reports the case of a 39 - year - old pregnant woman at 22 weeks of gestation with massive enlargement of bilateral breasts ( gigantomastia ) and presents the sonographic findings of this rare condition which shows different parenchymal patterns from those of normal breasts and is uncommonly seen . - pubmed
AIMS : Acute respiratory distress syndrome ( ARDS ) , one of the serious form of acute lung injury ( ALI ) , is the primary cause of death in patients with ALI . - pubmed
Therefore , the aim of the present study was to investigate protective effect of SND on ALI model induced by E. - pubmed
Helicobacter pylori chronic gastritis updated Sydney grading in relation to endoscopic findings and H. - pubmed
Helicobacter pylori ( Hp ) inhabits the stomach of & gt ; 50 % of humans and has been established as a major etiological factor in the pathogenesis of chronic gastritis , gastric atrophy , peptic ulcer disease , gastric adenocarcinoma , and gastric mucosa - associated lymphoid tissue lymphoma . - pubmed
This analytical study was conducted on 157 patients with dyspeptic gastritis . - pubmed
Since Staphylococcus aureus nasopharynx carriage is a known risk factor for PD infections and the oral cavity is a starting point for systemic diseases development , we aimed at comparing the oral staphylococci colonization between PD patients and controls and studying the association with PD - related infections . - pubmed
Although all patients presenting Staphylococcus epidermidis PD - related infections were also colonized in the oral cavity by the same agent , only 1 out of 7 patients with ESI caused by S. - pubmed
The association between oral Staphylococcus carriage and PD - related infections was present for S. - pubmed
The compound , 5 - aminolevulinic acid ( 5 - ALA ) is approved for fluorescence - guided resections of malignant gliomas in Europe and other countries for use in adults , but not for children . - pubmed
Benefit - risk profile of black cohosh ( isopropanolic Cimicifuga racemosa extract ) with and without St John 's wort in breast cancer patients . - pubmed
After breast cancer , even if receiving tamoxifen , patients using iCR / iCR + HP had significantly increased recurrence - free survival rates compared to non - users . - pubmed
A group of 32 healthy young adults with no history of a mood disorder ( Mage = 20.8 , SD = 2.1 ) and 62 remitted depressed young adults ( Mage = 21.1 , SD = 1.9 ) completed a neuropsychological battery . - pubmed
No differences were found between healthy controls and remitted depressed patients in either memory domain ( all ps & gt ; .05 ) and improvement in performance was exhibited over time for both groups ( p = 0.004 ) . - pubmed
Structural dynamics of bacteriophage P22 infection initiation revealed by cryo - electron tomography . - pubmed
We use cryo - electron tomography to study the infection initiation of phage P22 in Salmonella enterica serovar Typhimurium , revealing how a channel forms to allow genome translocation into the cytoplasm . - pubmed
About 70 % of BC patients will subsequently suffer disease relapse , manifesting as local , regional , or distant tumor recurrence , which clearly underscores the urgent need to discover novel recurrence inhibitors . - pubmed
Herein we report the novel activity of daily oral treatment with OC ( 10 mg / kg ) in preventing BC locoregional recurrence in a nude mouse xenograft model generated by orthotopic inoculation with BT-474 cells as a luminal type B model . - pubmed
Because of concomitant type 2 diabetes , all men were treated with metformin ( 2550 - 3000 mg daily ) . - pubmed
BACKGROUND : The ketogenic diet ( KD ) has been frequently used for the patients with drug - resistant epilepsy in recent years . - pubmed
Four patients had upper gastrointestinal bleeding , and one patient had hyperammonemic acute hepatic failure while receiving KD . - pubmed
Of the patients , 41.9 % had seizure - related ED admission . - pubmed
The frequency of status epilepticus was significantly lower in the patients who were on the KD for more than 6 months ( p & lt ; 0.01 ) . - pubmed
METHODS : Sixty - nine patients with tibial plateau fractures were examined . - pubmed
The external fixation group had shorter operation times ( 172.94 + - 50.00 min vs 253.86 + - 64.59 min ) , less bleeding volume ( 395.88 + - 121.10 mL vs 864.29 + - 238.12 mL ) , and fewer days ( 17.03 + - 5.03 days vs 30.17 + - 8.64 days ) of hospitalization compared to the internal fixation ( t - test , P = 0.00 ) ; subgroup analysis of all patients with complex tibial plateau fractures revealed that for patients with tibial plateau fracture type VI , the functional score of external fixation ( 26.79 + - 2.04 ) is better than that ( 25.54 + - 1.69 ) of internal fixation ( t- test , P = 0.026 ) and the overall infection rate of external fixation is lower than that of internal fixation ( chi2 - test , P = 0.047 ) . - pubmed
METHODS : We performed a retrospective review of patients at our institution who underwent an extended thymectomy for a thymoma from 1976 to 2015 . - pubmed
RESULTS : A total of 194 patients with thymoma were eligible for this study . - pubmed
PARTICIPANTS : Two hundred fifty - three eyes of 221 patients with exudative AMD . - pubmed
METHODS : Baseline data were collected on all eyes diagnosed with exudative AMD , which included ethnic data . - pubmed
RESULTS : Exudative AMD was diagnosed in 253 eyes of 221 patients . - pubmed
Polypoidal choroidal vasculopathy was noted in 51.6 % ( 81/157 ) of eyes with wet AMD in Asians , 31.9 % ( 23/72 eyes ) of eyes with wet AMD in white persons , and 28.6 % ( 4/14 eyes ) in a small group of Pacific Islanders . - pubmed
CONCLUSIONS : Polypoidal choroidal vasculopathy is more prevalent in Asian patients with exudative AMD , but is more prevalent than generally recognized in white patients . - pubmed
The patient underwent sigmoidectomy with the primary pathologic diagnosis of adenocarcinoma . - pubmed
In the patients with gastrointestinal malakoplakia , the presence of possible adjacent malignancy should be screened . - pubmed
BACKGROUND : Women with human immunodeficiency virus ( HIV ) have higher rates of abnormal cervical and vaginal cytology and , subsequently , of cervical and vaginal cancers . - pubmed
METHODS : For this study , patients with comorbid TMD and systemic / neurologic conditions were compared using clinical diagnostic markers , inflammatory , pain , tissue destruction enzymatic biomarkers , and functional magnetic resonance imaging ( fMRI ) activity of the brain , with and without a custom - made dental orthotic . - pubmed
There was a marked elevation of biomarkers in samples taken from TMJ of patients who were clinically diagnosed with TMD . - pubmed
The fMRI study of TMD patients showed an abnormal hyper - connected salience network and a diminished blood flow to the anterior frontal lobes when they did not wear their customized dental orthotics . - pubmed
MRgFUS Pallidothalamic Tractotomy for Chronic Therapy - Resistant Parkinson ' s Disease in 51 Consecutive Patients : Single Center Experience . - pubmed
Background : There is a long history , beginning in the 1940s , of ablative neurosurgery on the pallidal efferent fibers to treat patients suffering from Parkinson ' s disease ( PD ) . - pubmed
Patients reported an 88 % mean tremor relief and 82 % mean global symptom relief on the operated side and 69 % mean global symptom improvement for the whole body . - pubmed
Conclusion : MRgFUS PTT was shown to be a safe and effective intervention for PD patients , addressing all symptoms , with varying effectiveness . - pubmed
Chemoradiotherapy and radiotherapy alone in patients with esophageal cancer aged 80 years or older based on the Comprehensive Registry of Esophageal Cancer in Japan . - pubmed
The purpose of the present study was to evaluate the results of radiotherapy and chemoradiotherapy in patients aged 80 years or older with esophageal cancer in the Japanese Nationwide Cancer Database . - pubmed
METHODS : A total of 358 patients aged 80 years or older who were treated with radiotherapy alone or with chemoradiotherapy for esophageal cancer between 2009 and 2011 were enrolled . - pubmed
In multivariate analysis , chemoradiotherapy , early stage and squamous cell carcinoma were significantly favorable prognostic factors for OS in patients aged 80 years or older ( p & lt ; 0.001 , p & lt ; 0.001 and p = 0.0323 , respectively ) . - pubmed
CONCLUSION : Concurrent chemotherapy with radiotherapy for esophageal cancer in patients aged 80 years or older is a significantly favorable prognostic factor for OS . - pubmed
Nicotine , the main component of tobacco , is reportedly associated with the development and rupture of AAA . - pubmed
IS VAGINAL DELIVERY HARMFUL TO PATIENTS WITH PSEUDOXANTHOMA ELASTICUM ? - pubmed
BACKGROUND / PURPOSE : To investigate the effect of a vaginal delivery ( VD ) on retinal pathology in patients with pseudoxanthoma elasticum . - pubmed
All 14 consecutive women with pseudoxanthoma elasticum who visited the ophthalmology department during pregnancy and after delivery between 2010 and 2018 were included . - pubmed
RESULTS : Fourteen patients ( 15 deliveries ) were included , of whom 11 patients ( 79 % ) had a VD and three patients ( 21 % ) a secondary caesarian section . - pubmed
Data of three patients with VD ( four deliveries ) could not be assessed for ( sub)retinal hemorrhage within 10 weeks postpartum . - pubmed
All patients had angioid streaks in the central 5,500 microm of the posterior pole of both eyes . - pubmed
After delivery , no patient in the VD or caesarian section group presented with progression of angioid streaks or ( sub)retinal hemorrhage . - pubmed
CONCLUSION : Pushing during the expulsion phase of VD seems safe in pseudoxanthoma elasticum patients without active choroidal neovascularization , and the presence of angioid streaks alone should not be an indication for elective caesarian section . - pubmed
Update on the Treatment of Medullary Thyroid Carcinoma in Patients with Multiple Endocrine Neoplasia Type 2 . - pubmed
Effects of Combined Bushen Zhichan Recipe and Levodopa in a Rodent Model of Parkinson Disease : Potential Mechanisms . - pubmed
MATERIAL AND METHODS We validated the efficacy of a Bushen Zhichan recipe combined with levodopa in a rodent Parkinson disease model and explored its possible mechanisms . - pubmed
Methods : We evaluated the presence of Pseudomonas aeruginosa , Staphylococcus aureus , Stenotrophomonas maltophilia , Achromobacter xylosoxidans and Serratia marcescens in sputum and nasal lavage of 59 patients with CF , and also collected saliva and used toothbrushes from 38 of them . - pubmed
In this study , we attempted to quantitatively evaluate sensory symptoms in patients with cervical myelopathy according to lesion level using PainVision(R ) . - pubmed
The results were analyzed for their correlation with magnetic resonance imaging ( MRI ) data , visual analog scale ( VAS ) scores , and patient functional status assessed by the Japanese Orthopaedic Association ( JOA ) and JOA Cervical Myelopathy Evaluation Questionnaire ( JOACMEQ ) scores . - pubmed
This indicates that both the distribution and intensity of sensory abnormalities are important for neurological level diagnosis in patients with cervical myelopathy . - pubmed
Colletotrichum capsici is a major phytopathogen with a broad host range which causes anthracnose disease . - pubmed
BACKGROUND AND PURPOSE : Although developmental venous anomalies have been frequently studied in adults and occasionally in children , data regarding these entities are scarce in neonates . - pubmed
MATERIALS AND METHODS : We reviewed parenchymal abnormalities and angioarchitectural features of 41 neonates with developmental venous anomalies ( 20 males ; mean corrected age , 39.9 weeks ) selected through a radiology report text search from 2135 neonates who underwent brain MR imaging between 2008 and 2019 . - pubmed
At a patient level , multiplicity ( P = .002 ) was significantly associated with the presence of > = 1 complicated developmental venous anomaly . - pubmed
METHODS : Data on 97 patients with atrial fibrillation and hypertension treated in our hospital were collected from September , 2018 to December , 2019 . - pubmed
CONCLUSION : Our findings show that rs6843082 SNP leads to the warfarin dose response differences that were observed in patients with atrial fibrillation and hypertension . - pubmed
In this report , we detail a case of probable CIE in an 84 - year - old woman following a normal diagnostic coronary angiography ( CAG ) that involved 20 mL of the low - osmolar , non - ionic monomeric , iodine - based contrast agent iopromide ( Ultravist 370 ) . - pubmed
The patient was unconscious and presented with hemiparesis , hemianopia , recurrent seizures , and cardiac and respiratory arrest within minutes to hours following the procedure . - pubmed
Strawberry tongue is a useful diagnostic feature in various diseases such as Kawasaki disease , TSS , scarlet fever , and group A streptococcal pharyngitis . - pubmed
METHODS : We collected 587 CC samples , 41 colitis tissues and 114 pericarcinomatous tissues , as well as corresponding clinicopathological data about the patients who contributed them . - pubmed
Eighty - nine studies were identified examining healthy adults and patients with neuropsychiatric disorders including depression , chronic pain , post - stroke deficits , and movement disorders . - pubmed
officinale rhizome revealed their possibility in preventing the occurrence of atherosclerosis , unsafe levels of some trace elements were recorded in M. - pubmed
The Kaplan - Meier method was used to evaluate the 10 - year overall survival ( OS ) and 10 - year cancer specific survival ( CSS ) for patients with SBC . - pubmed
The incidence of SBC in RC patients who received RT was higher than the US general population ( SIR , 1.35 ; 95 % CI , 1.19 - 1.53 , P<0.05 ) , and decreased with increasing age at diagnosis , and increased with time since diagnosis . - pubmed
In the following study , estradiol and testosterone plasma concentration were measured and evaluated in 18 women with polycystic ovaries , as one of the factors involved in the antiestrogenic response to Clomiphene Citrate . - pubmed
[ Oxygen medicinal pulverization in the treatment of stenosing diseases of the respiratory tract in children ] . - pubmed
Twelve serum protein profiles in children with acute nonbacterial gastroenterocolitis . - pubmed
In thirty children hospitalized with acute benign , short - duration gastroenterocolitis , no obligate pathogens were isolated from stools . - pubmed
In 40 women who had received radiotherapy for gynecologic carcinoma , biopsy was performed because recurrence of the tumor was clinically and/or cytologically suspected . - pubmed
When appropriately stimulated ( even in the absence of phagocytosis ) , human polymorphonuclear leukocytes release and/or generate proinflammatory materials and substances capable of provoking tissue injury . - pubmed
The BP - positive samples were from 6 children with evidence of severe acute brain damage leading to death in 5 cases : i.e. - pubmed
, 2 term newborns with perinatal asphyxia , a 4 week - old child with severe convulsions , a 3 year - old boy with hypoxia due to laryngitis , and a 12 year - old girl with encephalitis . - pubmed
Experimental chronic renal failure in the rat by electrocoagulation of the renal cortex . - pubmed
Comparison of 5 - episisomicin ( Sch 22591 ) , gentamicin , sisomicin , and tobramycin in treatment of experimental Pseudomonas infections in mice . - pubmed
Infection of man and chimpanzees with the hepatitis B virus ( HBV ) is associated with diffuse hepatocellular infection and variable manifestations of disease which may not only reflect the character of the host immune response , but also depend upon differences in the cellular biology of this minimally cytopathic or noncytopathic agent . - pubmed
Current information of the biology and immunology of HBV and other viruses has been integrated into a hypothesis to explain the pathogenesis of injury and events associated with persistent infection . - pubmed
In 19 patients with meningiomas of the olfactory fossa the author established a certain development of the psychopathological symptomatology . - pubmed
No age - related changes in threshold were observed in mice of either strain . - pubmed
Permeability alterations and efficacy in patients with small bowel obstruction . - pubmed
One - hundred unselected children presenting with partial motor seizures were subjected to clinical work - up and cranial computed tomography ( CT scan ) . - pubmed
On these , 56 patients had either a ring ( 35 patients ) or a disc - like ( 21 patients ) enhancing lesion which coincided with the probable site of origin of the seizures in all cases . - pubmed
Four patients showed a spot of calcification in the area of the original lesion and another two showed a typical ' target sign ' , i.e. - pubmed
It is concluded that these ring or disc lesions represent tuberculomas which are , thus , the commonest cause of partial motor seizures in children in this area . - pubmed
The findings described here demonstrate that TW may occur in patients with brain tumor involving subcortical midline structures . - pubmed
Resistance to cytotoxic agents is a common clinical problem encountered in the treatment of human myelodysplastic syndromes ( MDS ) and acute myeloblastic leukaemia ( AML ) . - pubmed
In addition , peripheral blood or bone marrow cells from 66 patients with MDS and AML have been screened for gene amplification and 40 cases for increased mRNA expression . - pubmed
[ Detection of functional myocardial insufficiency in patients with ischemic heart disease during loading tests ] . - pubmed
Blood samples were collected twice weekly over a nine month period from 24 Thoroughbred racehorses in training at Newmarket to study the effects of daily training schedules and stage of oestrous cycle on serum enzyme levels and clinical signs of equine exertional myopathy . - pubmed
Traditional flat race training may not be ideal in this respect and it is suggested that , for horses with an observed tendency towards exertional myopathy , more consistent and longer periods of less strenuous exercise may be advantageous . - pubmed
[ Clinico - catamnestic study of patients with paroxysmal - progressive schizophrenia with a history of affective , anxiety - affective and affective - hallucinatory attacks in childhood / and full - blown hallucinatory - delusional attacks in adolescence ] . - pubmed
Clinical follow - up covered 40 patients with paroxysmal progressive schizophrenia with a history of 52 affective , anxiety - affective and affective - hallucinatory attacks at the age of 0 - 10 years and of 70 hallucinatory - delusional attacks at the age of 11 - 17 years and older . - pubmed
Therefore a single dose schedule was introduced with Netilmicin given to 600 patients suffering from uncomplicated gonorrhea in order to evaluate the efficacy and safety of the drug . - pubmed
Gonorrhea was also clinically cured in all patients . - pubmed
[ Estrogen excretion in patients with chorioepithelioma of the uterus ] . - pubmed
[ Lesions of vitamin E and selenium deficiencies in poultry and their pathogenesis ] . - pubmed
Effect of streptozotocin diabetes on the hypothalamic - pituitary - thyroid axis in the rat . - pubmed
Studies of the hypothalamic - pituitary - thyroid axis have been performed in streptozotocin ( STZ)-diabetic Wistar rats and their controls . - pubmed
The fact that diabetes caused a reduction in the hypothalamic TRH content indicates that the primary cause of pituitary - thyroid alterations in STZ - diabetic rats lies in the hypothalamus , although the metabolic imbalance induced by diabetes and , in less degree , by undernutrition could also be partly responsible for some of the described modifications . - pubmed
The late fetal effect of chronic alcoholization in two strains of mice ( RAP and RAP female x CBAT6 male ) was controlled . - pubmed
The importance of skin biopsy in patients presenting with suspected urticaria pigmentosa is emphasized . - pubmed
A case of paraganglioma of parasellar origin in a 7 - year - old girl is described . - pubmed
Further studies of the concentration of magnesium ion ( Mg ++ ) in blood from patients with autoimmune diseases . - pubmed
At an optimal concentration of magnesium , highly virulent wild strains of Yersinia enterocolitica serotype O : 8 , with an LD50 , for mice , of less than 10(3 ) cell intravenously , had an in - vitro requirement for calcium at 37 degrees C but not at 26 degrees C. Avirulent wild strains of Y. - pubmed
Successful treatment of anemia seems to improve the quality of life of cancer patients . - pubmed
Transfusion therapy should be considered more carefully in relation with some data showing the possible negative influence of allogeneic blood derivatives on the progression of tumors , especially in patients immunodeficient after high dose chemotherapy and actinotherapy . - pubmed
A 28 - year - old woman with epilepsy developed the new onset of paroxysmal tongue tingling during subdural electrode monitoring . - pubmed
Human T - lymphotropic virus type I - associated uveitis in patients with Graves ' disease treated with methylmercaptoimidazole . - pubmed
Human T - lymphotropic virus type I ( HTLV - I ) is responsible for a certain form of uveitis [ HTLV - I - associated uveitis ( HAU ) ] . - pubmed
A previous history of Graves ' disease has been reported in 9 - 17 % of the patients with HAU . - pubmed
Five of 25 HTLV - I - positive patients with Graves ' disease developed HAU . - pubmed
Within a few months before the onset of uveitis , 3 patients were hyperthyroid , and 2 were hypothyroid . - pubmed
In 2 of 5 patients , an exacerbation of uveitis occurred soon after the readministration of MMI for the relapse of hyperthyroidism . - pubmed
None of the 367 HTLV - I negative patients with Graves ' disease nor 22 HTLV - I - positive patients with chronic thyroiditis or nodular goiter developed uveitis . - pubmed
The furcation involvement of 100 molars in 25 patients suffering from moderate to advanced periodontitis was investigated . - pubmed
We used anti - AGE antibodies to localize AGEs within kidney specimens obtained from both diabetic and nondiabetic individuals . - pubmed
OBJECTIVES : The purpose of this study has been to investigate by ultrasonographic methods the flow velocities of cerebral arteries because increased blood viscosity due to haematocrit elevation can cause neurological symptoms in polycythaemia vera patients , because of the resulting decrease in cerebral flow . - pubmed
CONCLUSIONS : A decrease in cerebral flow could be a risk for multifocal micro - ischaemic cerebral infarctions leading , after several years , to a multi - infarct dementia ; an early reduction in erythrocyte burden should be very useful in polycythaemic patients in preventing lacunar lesions . - pubmed
The injection of antibodies induces the development of immunological memory ; as a result , the animals are primed to respond to the injection of influenza vaccine . - pubmed
From March 1991 to June 1993 50 patients with local advanced NSCLC ( mediastinoscopy obligatory ) have been entered into an ongoing trial with preoperative chemotherapy and simultaneous chemo-/radiotherapy , followed by re - mediastinoscopy and surgery . - pubmed
Suppression of tumorigenicity in human teratocarcinoma cell line PA-1 by introduction of chromosome 4 . - pubmed
Immature ovarian teratocarcinomas are highly malignant with only 30 - 60 % of patients surviving for 2 years after diagnosis . - pubmed
We have used microcell fusion to introduce individually tagged normal human chromosomes into the PA-1 human teratocarcinoma cell line . - pubmed
We conclude that there is a putative tumor suppressor gene on human chromosome 4 whose expression interferes with the tumorigenicity of PA-1 cells . - pubmed
A prospective one - year follow - up study with somatosensory potentials evoked by stimulation of the median nerve in patients with cerebral infarct . - pubmed
Somatosensory potentials evoked by stimulation of the median nerve ( median nerve SEPs ) were studied in a prospective and sequential series of 40 patients with first supratentorial and nonhaemorrhagic cerebral infarct . - pubmed
In 35 patients the SEPs were recorded three times during the first year after the stroke . - pubmed
The location of the infarcted zone was reflected in the number of detected abnormalities : most patients with infarct changes extending to the gray matter of the Rolandic cortex showed abnormalities in the median nerve SEPs , and all patients with involvement of both precentral and postcentral cortical gray matter had abnormal median nerve SEPs . - pubmed
In the entire patient group when both latency and amplitude abnormalities were included about half ( 48 % ) of the patients had abnormal median nerve SEPs a week after the stroke , 39 % 2 - 3 months after the stroke and 29 % about one year after the stroke . - pubmed
Occurrence of polyclonal B - cell activation after experimental infection with Yersinia enterocolitica O:3 . - pubmed
Changes of distribution of platelet activating factor in the lung of rats with hypoxic pulmonary hypertension . - pubmed
MATERIAL AND METHODS : Fifteen of 30 male Wistar rats were exposed to hypoxia for 3 weeks , and another 15 rats served as controls . - pubmed
RESULTS : The rats developed pulmonary hypertension and right ventricular hypertrophy after hypoxic exposure . - pubmed
Under the light microscope , PAF is distributed on the vascular and alveolar walls of normal lung , and the content of PAF in the lung of rats with hypoxic pulmonary hypertension are remarkably higher than those of normoxic controls . - pubmed
CONCLUSIONS : PAF plays not only a physiological role in the rat lung , but also a pathophysiologic role in hypoxic pulmonary hypertension . - pubmed
We have treated by the " rendezvous " technique two patients suffering from pancreatic fistula complicating pancreatic pseudocysts . - pubmed
[ Internal osteosynthesis after unstable pelvic ring fracture in a 3 - year - old child ] . - pubmed
Here we describe the rare case of a gastric duplication cyst in a 59 - year - old patient . - pubmed
Blood pressure profile in patients with microvascular angina . - pubmed
Normotensive patients with microvascular angina exhibit increased diastolic blood pressure and blood pressure loads during daily activities and decreased diurnal variation of systolic blood pressure , compared with age- and sex - matched normotensive controls . - pubmed
PURPOSE : To examine how different operative measures influence the surgical outcome in patients with fibrous dysplasia of bone . - pubmed
METHODS : 118 dysplastic fibrous lesions of bone were surgically treated and reviewed in 70 patients between 1983 to 1993 ( eleven years ) with a median follow - up of six and a half years . - pubmed
Reconstruction with cortical grafts or bone chips from the bone bank , if necessary in combination with a durable osteosynthesis in mechanically demanding locations , or solely bone cement in mechanically less demanding areas , reduces the revision rate in patients with monoostotic and polyostotic fibrous dysplasia . - pubmed
The aim of this study was to determine the accuracy of clinical tests compared to colour duplex imaging in patients with primary varicose veins using a prospective , blinded comparison study . - pubmed
A total of 44 patients ( 70 limbs ) with primary , previously untreated varicose veins presenting to the vascular laboratory of a university teaching hospital were studied . - pubmed
The patients underwent physical examination using the cough test , the tap test , Trendelenbergs ' test , Perthes ' test and hand - held Doppler ( HHD ) assessment prior to undergoing colour duplex scanning . - pubmed
The ability to produce experimental endolymphatic hydrops in the guinea pig secondary to surgical occlusion of the endolymphatic sac and duct has been useful in studying various aspects of Meniere ' s disease ( 2 ) . - pubmed
Evaluation of the potency of BIKEN inactivated Japanese Encephalitis vaccine and DNA vaccines in an intracerebral Japanese Encephalitis virus challenge . - pubmed
Fourteen girls and 11 boys with a median age of 20 months ( 2 months , 10 years ) presented with 26 separate tumors . - pubmed
Five patients ( all with diffuse type ) had up to 3 recurrences . - pubmed
CONCLUSIONS : Patients with focal lipoblastoma are unlikely to require further surgery after initial resection . - pubmed
Patients with diffuse lipoblastoma ( lipoblastomatosis ) are likely to have recurrent disease ( usually within 2 years ) and should undergo close follow - up . - pubmed
The clinical characteristics and the kinetics of the disposition of the hepatomegaly associated with acute , uncomplicated Plasmodium falciparum malaria were investigated in 162 children in an endemic area of Nigeria . - pubmed
Hepatomegaly was significantly more common in the younger than in the older children . - pubmed
In the children in whom hepatomegaly did not resolve , a reduction in liver size of & lt ; 17 % by the time parasitaemia was cleared ( usually on day 3 ) was associated with non - resolution of hepatomegaly by days 7 or 14 of follow - up . - pubmed
In the children who had complete clearance of parasitaemia and resolution of hepatomegaly , there was no significant relationship between the parasitaemia - derived conventional indices of therapeutic response [ i.e. - pubmed
In the children with drug - sensitive P. falciparum infections and in whom hepatomegaly completely resolved , the area produced by plotting liver size against time ( i.e. - pubmed
These results indicate that routine clinical measurement of the liver size in children with hepatomegaly during acute , uncomplicated , P. - pubmed
Prior stress ameliorates caerulein - induced pancreatitis in rats . - pubmed
Tobacco use in households with asthmatics . - pubmed
A total of 169 powder - naive patients ( mean age 40 years ) with asthma or chronic obstructive pulmonary disease ( COPD ) were enrolled in a randomized crossover comparison of both inhalers . - pubmed
We present a novel Fn - binding protein of group A streptococcus serotype M3 and M18 strains isolated from patients with toxic shock - like syndrome ( TSLS ) . - pubmed
Moreover , mortality was decreased in mice infected with the mutant strain in comparison to the wild type . - pubmed
These clinical features overlap considerably with other co - circulating respiratory viruses such as respiratory syncytial virus and parainfluenza virus . - pubmed
Pneumonia due to Mycoplasma hominis in a healthy adult . - pubmed
A case of pneumonia due to Mycoplasma hominis in a healthy adult is presented . - pubmed
The emergence of Ph- , trisomy -8 + cells in patients with chronic myeloid leukemia treated with imatinib mesylate . - pubmed
OBJECTIVE : To describe clinical and laboratory features of a cohort of patients with chronic myelogenous leukemia ( CML ) who developed Ph(- ) , trisomy 8(+ ) metaphases while on treatment with imatinib mesylate . - pubmed
PATIENTS AND METHODS : Conventional cytogenetics and triple - color interphase fluorescence in situ hybridization were used to identify 5 of 310 studied patients who , on follow - up analysis , had Ph(- ) , trisomy 8(+ ) cells while on therapy . - pubmed
All patients developed grade 3 or 4 neutropenia and thrombocytopenia during treatment . - pubmed
CONCLUSIONS : While on treatment with imatinib mesylate a small group ( less than 5 % ) of patients with CML developed Ph(- ) trisomy 8(+ ) clone associated with pancytopenia . - pubmed
A 61 - year - old man with congestive heart failure was referred to our hospital and diagnosed as atrial septal defect ( ASD ) [ Qp / Qs = 1.6 ] with chronic atrial fibrillation . - pubmed
MATERIALS AND METHODS : Twelve consecutive patients with their first middle cerebral artery ( MCA ) infarction were included . - pubmed
Specific inhibition of Hh signalling by the naturally occurring plant alkaloid cyclopamine provides the opportunity for pharmacologic assessment of the role of Hh signalling in these tumors . - pubmed
METHODS : 63 approximal carious lesions were restored in 38 patients by two experienced operators . - pubmed
Consequently , we performed a phase II trial in patients with advanced melanoma to explore this approach . - pubmed
Six patients continue to show no signs of tumor progression for 3 + , 5 + , 10 + , 24 + , 60 + , and 72 + months . - pubmed
METHODS : Eighty - five patients with postoperative nausea and vomiting were included in this prospective , single - blind study . - pubmed
56 lesions were treated ; 26 bedsores , 11 venous sores , 10 mixed lesions and 9 other types , they had an average presence on the patient of 270 ( + /- 684 ) days , the medium was 85 days and the mode 365 days . - pubmed
[ Antiatherogenic effect of Huajiao volatile oil on experimental atherosclerosis in guinea pigs ] . - pubmed
METHODS : Atherosclerotic guinea pig models were duplicated by feeding high lipid forage . - pubmed
CONCLUSION : Huajiao volatile oil has an inhibitory effect on the development of experimental atherosclerosis lesions in guinea pigs . - pubmed
The purpose of this study was to identify the metabolic features that place patients with type 2 diabetes at increased risk for uric acid nephrolithiasis . - pubmed
Patients with type 2 diabetes and UASF had lower 24 - h urine pH than NV . - pubmed
With increasing urine sulfate , NV and patients with type 2 diabetes had a similar rise in urine ammonium , whereas in UASF , ammonium excretion remained unchanged . - pubmed
The main risk factor for uric acid nephrolithiasis in patients with type 2 diabetes is a low urine pH. - pubmed
Higher body mass and increased acid intake can contribute to but can not entirely account for the lower urine pH in patients with type 2 diabetes . - pubmed
METHODS : Thirteen patients who were diagnosed with HHS between 1995 and 2003 were retrospectively assessed . - pubmed
The mean age of HHS patients was 38.6 + /- 10 years ( 5 women , 8 men ) . - pubmed
HHS was related to an infectious etiology in 6 of 13 patients : tuberculosis ( n=3 ) , cytomegalovirus ( CMV ) infection ( n=2 ) , Escherichia coli ( E. - pubmed
coli)-associated septicemia ( n=1 ) , but HHS was cured by antimicrobial therapy in only 2 of them ( 1 with tuberculosis , the other with E. - pubmed
HHS was related to an infectious etiology in 2 patients unresponsive to antimicrobial treatment , and of unknown etiology in 4 patients . - pubmed
CONCLUSIONS : We concluded that when HHS does not respond to treatment of the underlying infection , or is of unknown etiology in immunocompromised patients , high - dose IVIg therapy should be administered . - pubmed
We examined if neocortical epileptogenic regions can be circumscribed by quantifying local long - range temporal ( auto-)correlations ( LRTC ) with detrended fluctuation analysis of seizure - free ongoing subdural EEG activity in 4 frequency bands in 5 patients . - pubmed
A 67 - year - old man initially presented with an 8 - year history of right trigeminal neuralgia . - pubmed
This article reports the case of an intraosseous schwannoma located in the mandibular symphysis of an 11 - year - old boy . - pubmed
The diagnosis of BO was based on the presence of respiratory symptoms and air - trapping on expiratory lung high - resolution computed tomography in all patients , associated with irreversible airflow obstruction in seven cases . - pubmed
However , the pathogenic mechanism of dengue virus ( DV)-induced hemorrhage awaits clarification . - pubmed
We established a mouse model of DV hemorrhage using immunocompetent C57BL / 6 mice by injecting DV serotype 2 strain 16681 intradermally . - pubmed
While inoculation of 3 x 10(9 ) PFU of DV induced systemic hemorrhage in all of the mice by day 3 of infection , one out of three of those injected with 4 x 10(7 ) to 8 x 10(7 ) PFU developed hemorrhage in the subcutaneous tissues . - pubmed
The mice that were inoculated with 4 x 10(7 ) to 8 x 10(7 ) PFU but that did not develop hemorrhage were used as a basis for comparison to explore the pathogenic mechanism of dengue hemorrhage . - pubmed
The results showed that mice with severe thrombocytopenia manifested signs of vascular leakage and hemorrhage . - pubmed
A reappraisal of the safety of 50 % dextrose administration in patients with hypoglycemia . - pubmed
METHOD : We have evaluated 40 women , divided into four groups by the model of postoperative pain treatment : control group ( only opioid ) and experimental group ( combination of i.v . - pubmed
Protective role of lactobacilli in Shigella dysenteriae 1 - induced diarrhea in rats . - pubmed
Nevertheless , in vivo effects of Lactobacillus during Shigella infection have not been evaluated . - pubmed
The present study evaluated the effect of Lactobacillus rhamnosus and Lactobacillus acidophilus on neutrophil infiltration and lipid peroxidation during Shigella dysenteriae 1 - induced diarrhea in rats . - pubmed
METHOD : Thirty patients with perennial allergic rhinitis were treated by specific immunotherapy for three years . - pubmed
Controlled group were 30 perennial allergic rhinitis patients who were treated with medication only ( antihistamines and intranasal corticosteroids ) when necessary . - pubmed
Healthy group were 10 healthy people without allergic rhinitis . - pubmed
( 3 ) Thirty patients with allergic rhinitis received 3530 times immunotherapy , their local and systemic side - effect were observed , recorded and analyzed during the treatment , the number of patients who got systemic side - effect was 4 cases , the percent of side - effect was 0.17 % ( 6/3530 ) ; the number of patients who got local side - effect was 12 cases , the percent of local side - effect was 1.53 % ( 54/3530 ) . - pubmed
With a lifetime incidence of up to 12 % in man and 6 % in woman , nephrolithiasis is a major health problem worldwide . - pubmed
In this brief review , we summarize the studies assessing the heritability of hypercalciuria and pinpoint recently identified human genetic disorders as well as relevant animal models that provided new insights into the segment - specific tubular handling of calcium and the pathophysiology of renal hypercalciuria and kidney stones . - pubmed
Predictive factors for tumor response and long term outcome should be developed for a better selection of the patient population who will benefit from these treatments . - pubmed
Borrelia burgdorferi , the causative agent of Lyme disease , activates multiple signalling pathways leading to induction of pro - inflammatory mediators at sites of inflammation . - pubmed
The effect of monohydroxyethylrutoside on doxorubicin - induced cardiotoxicity in patients treated for metastatic cancer in a phase II study . - pubmed
The purpose of this study was to investigate the cardioprotective effect of the semisynthetic flavonoid 7 - monohydroxyethylrutoside ( monoHER ) on doxorubicin ( DOX)-induced cardiotoxicity in a phase II study in patients with metastatic cancer . - pubmed
Eight patients with metastatic cancer were treated with DOX preceded by a 10 min i.v . - pubmed
Although there is a considerable variability in few investigated patients , it was indicative that monoHER enhanced DOX - induced cardiotoxicity . - pubmed
However , the antitumour activity of DOX seemed better than expected : three of the four patients with metastatic soft - tissue sarcoma had a partial remission and the fourth patient stable disease . - pubmed
It is likely that the relatively high dose of monoHER is responsible for the lack of cardioprotection and for the high response rate in patients with soft - tissue sarcoma possibly by depleting the glutathione defense system in both heart and tumour . - pubmed
In vivo porcine model of reperfused myocardial infarction : in situ double staining to measure precise infarct area / area at risk . - pubmed
OBJECTIVES : The aim of this study is to evaluate a catheter - based porcine model for reperfused myocardial infarction and investigate the appropriate location and duration of the occlusion . - pubmed
Myocardial infarction was successfully induced in all 72 animals and in situ double - staining with Evans blue dye and 2,3,5 - triphenyltetrazolium chloride was performed to delineate area at risk for ischemia and infarcted myocardium . - pubmed
The current study demonstrated that 60 - min mid LAD occlusion can be the most feasible to serve as a porcine reperfused myocardial infarction model . - pubmed
Aeromonas sobria prostatitis and septic shock in a healthy man with chronic alcoholic consumption . - pubmed
Prostate infection caused by Aeromonas sobria has not been reported in the literature . - pubmed
Based on our rare case , we suggest to clinical physicians that prostatitis might be considered in healthy male patients with A. - pubmed
PURPOSE : To investigate the safety , tolerability , and bioactivity of intravenous infusions of bevacizumab in patients with choroidal neovascularization ( CNV ) attributable to causes other than age - related macular degeneration . - pubmed
METHODS : Ten patients with CNV received infusions of 5 mg / kg of bevacizumab . - pubmed
All patients except one showed a reduction in area of CNV with a median reduction of 43 % . - pubmed
CONCLUSIONS : Despite the small number of patients studied , the marked improvement in VA accompanied by prominent reductions in foveal thickness , fluorescein leakage , and area of CNV suggest a beneficial effect . - pubmed
It may be worthwhile to consider further evaluation of systemic bevacizumab in young patients with CNV . - pubmed
No patients had thigh pain and no patients had aseptic loosening . - pubmed
Controlled hypotension in adults undergoing choroidal melanoma resection : comparison between the efficacy of nitroprusside and magnesium sulphate . - pubmed
METHODS : Forty adult patients undergoing choroidal melanoma resection and anaesthetized with 2.5 mg kg(-1 ) propofol , followed by a constant infusion of 120 microg kg(-1 ) min(-1 ) , and remifentanil 1 microg kg(-1 ) , followed by a continuous infusion of 0.25 microg kg(-1 ) min(-1 ) , were randomly assigned to two groups to receive either magnesium sulphate or sodium nitroprusside . - pubmed
CONCLUSION : Magnesium sulphate controlled hypotension , reduced intraoperative pressure and provided good surgical conditions for choroidal melanoma resection with no need for additional use of a potent hypotensive agent in adults . - pubmed
Cardiac effects of continuous and bilevel positive airway pressure for patients with heart failure and obstructive sleep apnea : a pilot study . - pubmed
BACKGROUND : Obstructive sleep apnea ( OSA ) is prevalent in patients with heart failure . - pubmed
Treatment with continuous positive airway pressure ( CPAP ) improves systolic function in patients with heart failure . - pubmed
The intermediate - term effect of bilevel PAP on left ventricular ejection fraction ( LVEF ) in patients with stable heart failure and OSA has not been compared to the effect of CPAP . - pubmed
CONCLUSION : This pilot randomized controlled trial suggests that bilevel PAP is superior to CPAP in improving LVEF in patients with systolic dysfunction and OSA . - pubmed
BACKGROUND : Approximately one - half of hypertensive individuals are salt sensitive , and animal models of human hypertension also exhibit increased blood pressure when exposed to high - salt diets . - pubmed
Incidental hypokalemia in ambulatory patients . - pubmed
There were no differences between patients with ABECB treated with SSPs and those treated with trimethoprim , alone or in combination with a sulfonamide , in treatment success ( intention - to - treat patients : n = 262 , odds ratio [ OR ] 1.68 , 95 % confidence interval [ CI ] 0.91 - 3.09 ; clinically evaluable patients : n = 246 , OR 1.59 , 95 % CI 0.79 - 3.20 ) or number of drug - related adverse events in general ( n = 186 patients , OR 0.37 , 95 % CI 0.11 - 1.24 ) , frequency of diarrhea or skin rashes , or number of withdrawals due to adverse events ( n = 179 patients , OR 0.27 , 95 % CI 0.07 - 1.03 ) . - pubmed
METHODS : The association of fentanyl and 0.75 % bupivacaine for eye blockade and postoperative analgesia was evaluated in 164 patients undergoing cataract extraction with implantation of intraocular lens ( extracapsular technique ) . - pubmed
Drug - induced acute pancreatitis in children receiving chemotherapy for acute leukemia : does propofol increase the risk ? - pubmed
BACKGROUND : The use of propofol is controversial in patients with a history of acute pancreatitis or those taking drugs , including certain chemotherapeutic drugs , that are associated with pancreatitis . - pubmed
METHODS : To investigate this issue , we reviewed the medical records of all children who were diagnosed with pancreatitis while receiving chemotherapy for acute leukemia during a 5 - year period . - pubmed
CONCLUSION : Propofol can be considered for general anesthesia in children who are receiving chemotherapeutic drugs that are themselves associated with acute pancreatitis or those who have a history of chemotherapy - induced pancreatitis . - pubmed
While infection with C. - pubmed
difficile strains of public health significance continue to emerge , and reliable genotyping methods for epidemiological investigations and global surveillance of C. - pubmed
Six women later developed PE and 9 remained normotensive . - pubmed
CONCLUSION : This small observational study showed that serum CC is raised as early as the second trimester in women who subsequently develop PE in third trimester . - pubmed
Leptospirosis is a neglected infectious disease that constitutes a threat to both humans and animals . - pubmed
Acute toxicity of nitrite and ammonia to Daphnia similoides of different developmental stages : using the modified Gaussian model to describe . - pubmed
Shigella is a Gram - negative human pathogen that causes diarrhea in humans . - pubmed
METHODS : A retrospective observational study was conducted in all critically ill patients who had been prescribed nutritional support , throughout one year , in an Intensive Care Unit . - pubmed
These sensitive and specific ancillary tools are useful for confirming ambiguous diagnoses suspected by light microscopy and for guiding therapeutic decisions , assessing prognosis , and monitoring patients for residual neoplastic disease after therapy . - pubmed
Among 161 patients with acute myeloid leukemia ( non - M5 subtype ) , estimated median overall survival was 39 , 29 , and 37 months , respectively , in the daunorubicin , standard - dose homoharringtonine , and high - dose homoharringtonine treatment groups ( P = .53 ) . - pubmed
In the 93 patients with acute myeloid leukemia - M5 subtype , there was a significant difference in estimated median overall survival : 24 , 24 , and 52 months , respectively , in the daunorubicin , standard - dose homoharringtonine , and high - dose homoharringtonine treatment groups ( P = .003 ) . - pubmed
High - dose homoharringtonine does not clearly increase the complete remission rate of elderly patients with acute myeloid leukemia . - pubmed
However , in the subset of elderly patients with acute monocytic leukemia , high - dose homoharringtonine as a first - line regimen prolonged overall survival with minimal toxicity . - pubmed
These findings demonstrated the presence of both genome - wide and segmental duplications in the apple genome and provided further insights into the complex polyploid ancestral origin of the apple . - pubmed
In the present report we show that tamoxifen is endowed with significant inhibitory property against human platelet aggregation . - pubmed
Twenty individuals ( 13 females and 7 males , average age 40.1 + - 13.4 ) with stabilization classification LBP and 19 controls ( 10 females and 9 males , average age 30.3 + - 8.7 ) participated in this study . - pubmed
BACKGROUND : In Honduras , chloroquine and primaquine are recommended and still appear to be effective for treatment of Plasmodium falciparum and Plasmodium vivax malaria . - pubmed
Because of the environmental and industrial importance of the class of aromatic amines , we apply the approach to a previously published QSAR on the Salmonella typhimurium mutagenicity of these chemicals . - pubmed
Their cooperation , by completing a structured questionnaire and allowing the direct observation of three subjects , enabled us to carry out a study on a total of 75 patients suffering from AH . - pubmed
BACKGROUND : Mycobacterium tuberculosis , the causative agent of tuberculosis , has a remarkable ability to usurp its host 's innate immune response , killing millions of infected people annually . - pubmed
Variants of human papillomavirus ( HPV ) type 31 have been shown to be related both to risk of cervical lesions and racial composition of a population . - pubmed
Correlation of conventional and conformal plan parameters for predicting radiation pneumonitis in patients treated with breast cancer . - pubmed
Only four patients developed symptomatic RP , 4 with 4 - FRT and one with 2 - FRT . - pubmed
However , delayed RAE could cause the patient to reach a life - threatening cachexic state and could increase the risk of morbidity and mortality due to severe proteinuria - induced hypoalbuminemia . - pubmed
The use of ( 41 ) C kinetic modeling in the Ossabaw swine provides an approach for assessing soft tissue calcification in an atherosclerotic and normal state to address research gaps . - pubmed
reported significant improvement in neurological outcomes in MS patients who underwent percutaneous transluminal angioplasty ( PTA ) . - pubmed
OBJECTIVES : To retrospectively evaluate the neurological outcomes in MS patients who underwent PTA . - pubmed
Patients with clinically isolated syndrome or progressive forms of MS were excluded . - pubmed
Primary endpoint was the proportion of relapse - free patients at 1 year . - pubmed
There was no difference among the patients who stopped their DMTs with respect to relapses , EDSS score or new MRI activity . - pubmed
The basis for initial selection of endemic atoxigenic strains of A. - pubmed
Efficacy and safety of autologous bone marrow - derived stem cell transplantation in patients with type 2 diabetes mellitus : a randomized placebo - controlled study . - pubmed
METHODS : Nineteen subjects , 14 men and 5 women ( ages , 20 - 39 years ) without temporomandibular disorders were examined . - pubmed
Anticoagulant therapy is the first line of treatment in CVST but may not be applicable in patients with head trauma . - pubmed
Here , we report on the treatment of 2 patients with CVST . - pubmed
Seventeen patients had an excessive deformity ( & gt;15 of varus or valgus ) , twenty - one had moderate valgus alignment ( 5 to 15 of valgus ) , twenty - seven had moderate varus alignment ( 5 to 15 of varus ) , and thirty - eight had neutral alignment ( & lt;5 of varus or valgus ) . - pubmed
The diploid SVP5 line ( 2n=2x=24 ) and tetraploid regenerants of S. - pubmed
We have evaluated both invariant and non - invariant populations in the blood and synovial fluid from patients to assess feasibility of NKT cell - directed manipulations in RA . - pubmed
RESULTS : We have confirmed a proliferative defect of iNKT cells in both peripheral blood and synovial fluid from RA patients , but no changes in baseline frequencies . - pubmed
MATERIALS AND METHODS : We reviewed 33 consecutive patients with type 2 diabetes admitted to Osaka University Hospital for glycemic control . - pubmed
Hemodynamically stable patients with renal injury can be managed conservatively . - pubmed
The intensive care unit mortality rate was 15 % , and 38 % of the patients had postoperative complications . - pubmed
Myocardial ischemia was diagnosed in only 1.9 % of the patients . - pubmed
Recently , there has been controversy about the relationship between the number of lymph nodes removed and survival of patients diagnosed with lymph node - negative breast cancer . - pubmed
Patients were stratified into two groups ( Group A , 10 or fewer tumor - free lymph nodes removed ; Group B , more than 10 tumor - free lymph nodes removed ) . - pubmed
Our results revealed that the risk of death from breast cancer was significantly associated with patient age , marital status , histologic grade , tumor size , and adjuvant therapy . - pubmed
The 5- and 10 - year survival rates for patients with 10 or fewer tumor - free lymph nodes removed was 88.0 % and 66.4 % , respectively , compared with 69.2 % and 51.1 % , respectively , for patients with more than 10 tumor - free lymph nodes removed . - pubmed
For patients with 10 or fewer tumor - free lymph nodes removed , the adjusted hazard ratio ( HR ) for risk of death from breast cancer was 0.579 ( 95 % confidence interval , 0.492 - 0.687 , P & lt ; 0.001 ) , independent of patient age , marital status , histologic grade , tumor size , and adjuvant therapy . - pubmed
To examine how fish consumption affects the development and prevalence of MetS , we systematically reviewed cross - sectional , prospective cohort , and intervention studies conducted among adults ( humans ) and , reporting consumption of fish or seafood as being related to MetS ( prevalence or incidence ) , where MetS was defined via an established definition . - pubmed
METHODS : Hyperoxic lung injury was induced by exposing to 60 % O2 in Spraque - Dawley rats within 6 hours after birth . - pubmed
Postoperative complications in patients with obstructive sleep apnea : a meta - analysis . - pubmed
CONCLUSIONS : Surgical patients with OSA are at increased risk of postoperative respiratory failure , cardiac events , and ICU transfer . - pubmed
The impact of neuropathic pain and other comorbidities on the quality of life in patients with diabetes . - pubmed
We were interested in how neuropathic pain impairs the quality of life in diabetic patients and what is the role of comorbidities in this condition . - pubmed
METHODS : The study included 80 patients with painful DPN ( group " P " ) and 80 patients with DPN , but without neuropathic pain ( group " D " ) . - pubmed
Clinically , the most pronounced differences between two groups were noted in sleeping disorders and problems regarding micturition and defecation , which were significantly more expressed in group P. The similar situation was with walking distance and color - doppler sonography of carotid arteries , which were significantly worse in group P. Consequently , subjects in group P were more medicated than the patients in group D , particularly with tramadol , antiepileptics and antidepressants . - pubmed
Parthenolide ( PTL ) is a sesquiterpene lactone isolated from feverfew and exhibits potent antitumor activity against various cancers . - pubmed
Since certain flavonoids are potent bacterial efflux pump inhibitors , we assessed morin , rutin , quercetin , hesperidin , and ( + ) - catechin for their combined activity with the antibiotics ciprofloxacin , tetracycline , erythromycin , oxacillin , and ampicillin against drug - resistant strains of Staphylococcus aureus , including methicillin - resistant S. - pubmed
The cytotoxicity of the flavonoids was additionally evaluated in a mouse fibroblast cell line . - pubmed
MATERIALS AND METHODS : A total of 30 patients ( mean age , 19.5 years ) received 147 direct composite additions for teeth recontouring and diastema closures . - pubmed
We chose pathogen bacterium Pseudomonas aeruginosa as a model strain and evaluated the inhibitory effects of gentamicin and ciprofloxacin . - pubmed
RESULTS : Unlike the robust beneficial effect on anastomosis under uncomplicated conditions , here GM6001 had a negative impact on anastomotic wound healing following colonic obstruction and substantially ( p=0.004 ) more rats in the GM6001 group ( 75 % ) than in the control group ( 11 % ) had developed anastomotic leakage . - pubmed
Synovial fluid total protein concentration as a possible marker for canine idiopathic polyarthritis . - pubmed
Idiopathic polyarthritis ( IPA ) is a very common inflammatory arthropathy in the dog . - pubmed
METHODS : This prospective study included 37 hips in 37 patients ( mean age 26 + - 9 years ) who were treated with periacetabular osteotomy for symptomatic acetabular dysplasia and had preoperative and 1 - year follow up dGEMRIC scans . - pubmed
Patients were eligible if they had symptomatic acetabular dysplasia with lateral center - edge angle & lt ; 20 and no or minimal osteoarthritis . - pubmed
METHODS : A total of 109 patients with AMI and 58 healthy subjects as control group were included in the study . - pubmed
METHODS : Between February 2010 and October 2013 , 147 patients with acute aortic dissection ( AAD ) were divided into Group 1 ( Stanford A , n = 59 ) and Group 2 ( Stanford B , n = 88 ) . - pubmed
Suppression of the PLT activation might be future targets of therapy in the prevention of systemic inflammation in AAD patients . - pubmed
We analyzed patients with BC before and after NACT for disseminated tumor cells ( DTCs ) in the bone marrow(BM ) ; comprehensively characterized circulating tumor cells ( CTCs ) , including stem cell - like CTCs ( slCTCs ) , in blood to prove the effectiveness of treatment on these cells ; and correlated these findings with response to therapy , progression - free survival ( PFS ) , and overall survival ( OS ) . - pubmed
Thus , these patients might benefit from additional second - line treatment protocols including bisphosphonates for the eradication of DTCs . - pubmed
The anti - inflammatory and anti - apoptotic effects of gallic acid against mucosal inflammation- and erosions - induced by gastric ischemia - reperfusion in rats . - pubmed
The present study aimed to evaluate the protective effect of gallic acid on gastric mucosal lesions caused by ischemia - reperfusion ( I / R ) injury in rat . - pubmed
Forty male rats were randomly divided into sham , control ( I / R injury ) and three gallic acid - pretreated groups . - pubmed
Pretreated rats received gallic acid ( 15 , 30 or 60 mg kg(-1 ) , intraperitoneally ) 30 min prior to the induction of I / R injury . - pubmed
OBJECTIVES : To assess and clearly define the repigmentation patterns in a series of patients with vitiligo , correlating these with clinicoepidemiological characteristics . - pubmed
METHODS : Patients with vitiligo seen at least at twice ( initial consultation and follow - up visit ) in the Department of Paediatric Dermatology , Hopital Pellegrin des Enfants , Bordeaux University Hospital from 2006 to 2014 were included . - pubmed
RESULTS : There were 109 patients ( 64 female , 45 male ) mostly with Fitzpatrick skin type III ( n = 67 , 61 % ) . - pubmed
OBJECTIVES : The aim of this study was to evaluate sex differences in plaque morphology in stable coronary artery disease ( CAD ) patients using a multimodality intravascular imaging approach . - pubmed
METHODS : We retrospectively analyzed data from 383 patients with stable CAD who were referred for angiography and underwent optical coherence tomography . - pubmed
BACKGROUND : Obesity is a risk factor for breast cancer in postmenopausal women and is associated with decreased survival and less favorable clinical characteristics such as greater tumor burden , higher grade , and poor prognosis , regardless of menopausal status . - pubmed
Alterations of pathways involved in cell cycle control , tumorigenesis and metabolism may promote cellular proliferation and provide a molecular explanation for less favorable outcome of obese women with breast cancer . - pubmed
Characterization of anti - leukemia components from Indigo naturalis using comprehensive two - dimensional K562 / cell membrane chromatography and in silico target identification . - pubmed
In this study , a new strategy combining comprehensive two - dimensional K562 / cell membrane chromatographic system and in silico target identification was established to characterize active components from Indigo naturalis , a famous TCM herb that has been widely used for the treatment of leukemia in China , and their targets . - pubmed
INTRODUCTION : The purpose of this study was to compare the isolated effects of bonded and conventional spurs on the craniofacial and dentoalveolar complexes of patients in the mixed dentition with anterior open bite . - pubmed
METHODS : The sample included 68 subjects with anterior open bite and Class I malocclusion . - pubmed
The aim of this study was to analyze the clinical characteristics and to explore the rational treatment of patients with breast SCC . - pubmed
METHODS : Between 04/2014 and 04/2015 , 16 patients with deep partial- to full - thickness burns of the upper extremities underwent enzymatic debridement ( ED ) in our Burn Center and were evaluated for extent of additional surgery , wound healing , pain management and functional parameters . - pubmed
Time from injury to ED was 24.4 h and patients were able to start physical therapy after 2.0 days but suffered from prolonged wound closure ( 28.0 days ) . - pubmed
Asthma therapy is changing from a ' one size fits all ' therapy to a ' precision medicine ' model , where we may prescribe the most appropriate treatment for each patient . - pubmed
Whole blood gene expression profiling was performed in 17 and 9 patients diagnosed with ET and PMF , respectively . - pubmed
Our 7 - gene signature may be a useful tool to differentiate between genuine ET and prePMF but needs to be validated in a larger cohort of " ET " patients . - pubmed
This study was designed to determine the types of histological alterations seen in Nigerian patients with NERD . - pubmed
METHODS : This was a prospective cross - sectional study in which mucosal biopsy was taken from the lower esophagus in patients with NERD . - pubmed
RESULTS : There were 68 patients with NERD and 60 patients with nonulcer dyspepsia . - pubmed
Results : We performed 30 ( 47 % ) uniportal thoracoscopic pleural decortication and 34 ( 53 % ) open decortication for empyema in stage II ( 40 % ) or III ( 60 % ) obtaining a complete debridement and decortication in all patients . - pubmed
A large number of cellular and animal models for BTHS have been established to elucidate how mitochondrial dysfunction induces sarcomere disorganization and reduced contractility , resulting in dilated cardiomyopathy in vivo . - pubmed
BACKGROUND : Calciphylaxis is a serious complication in patients with chronic kidney disease associated mineral and bone disorder . - pubmed
So far , there are no definite diagnostic and therapeutic guidelines which may prevent the devastating outcome in many calciphylaxis patients . - pubmed
Based on this experience we discuss a systematic diagnostic and therapeutic approach in patients with calciphylaxis . - pubmed
CASE PRESENTATION : We report a patient with severe calciphylaxis . - pubmed
CONCLUSIONS : This case illustrates that laboratory tests can not reliably differentiate between high and low bone turnover in calciphylaxis patients . - pubmed
METHODS : We studied 93 patients ( 8.0 % ) with locally advanced unresectable pancreatic cancer without distant metastases from among a total group of 1168 patients who were diagnosed with pancreatic cancer from March 2005 to November 2015 at the Kochi Health Sciences Center , Kochi , Japan . - pubmed
On the other hand , the overall 1- , 3- and 5 - year survival rates in patients who were reclassified as having resectable tumour after CRT were 71.3 % , 39.2 % and 23.5 % , respectively . - pubmed
We aimed to examine the relationship between HP infection and severity of coronary atherosclerosis in patients with chronic CAD . - pubmed
CONCLUSION : It is likely that HP infection is not a risk factor for the severity of coronary atherosclerosis in chronic CAD patients . - pubmed
STUDY OBJECTIVE : To evaluate the feasibility , safety , and outcome of laparoscopic modified Davydov vaginoplasty in subjects with partial androgen insensitivity syndrome ( PAIS ) . - pubmed
CONCLUSION : This is the first study reporting the outcomes of laparoscopic modified Davydov vaginoplasty in subjects with PAIS . - pubmed
Postoperative long - term outcomes were comparable with those achieved in women with Rokitansky syndrome . - pubmed
BACKGROUND : Hepatitis B virus ( HBV ) carriers worldwide number approximately 240 million people and around 780,000 people die every year from HBV infection . - pubmed
After hatching , 120 male chicks with average body weight ( BW ) were randomly allocated into each treatment group for a 7 - day feeding trial . - pubmed
METHODS : This is a prospective , controlled , clinical study evaluating the impact of UV irradiation on the electrical impedance spectroscopy scores of benign nevi in 50 patients undergoing phototherapy . - pubmed
To this end , benign nevi of patients with a medical indication for phototherapy will be measured by electrical impedance spectroscopy before , during and after UV irradiation . - pubmed
MATERIALS AND METHODS : Patients with tinnitus presenting to our center retrospectively had their nerve size assessed by MRI . - pubmed
Rapid wound healing and subsequent formation of the apical epithelial cap ( AEC ) are believed to be required for successful appendage regeneration in amphibians . - pubmed
Methods : A total of 301 outpatients ( men , 116 ; women , 185 ; mean age , 65 + - 11 years ) , with no history of cardiovascular diseases , undergoing treatment for diabetes mellitus were enrolled . - pubmed
Early brain injury ( EBI ) plays a key role in determining the prognosis of patients suffering from subarachnoid hemorrhage ( SAH ) . - pubmed
Rats received intraperitoneal administration of resveratrol or vehicle immediately after establishing SAH model . - pubmed
We found that mortality and brain edema were significantly lower , whereas the neurological score was higher for resveratrol - treated rats . - pubmed
HE staining showed that resveratrol significantly reduced the neuronal pyknosis and swelling in the resveratrol - treated rats compared with SAH rats . - pubmed
A major contributing factor associated with increased cardiac mortality in patients with schizophrenia ( SCZ ) seems to be a dysfunction of the autonomic nervous system ( ANS ) . - pubmed
Prospective trials aimed at examining the cardiovascular implications of acute psychosis treatment in patients with schizophrenia are warranted . - pubmed
METHODS The authors performed a prospective cohort study of craniosynostosis patients ( n = 34 ) referred to a single national ( tertiary ) craniofacial unit . - pubmed
Controls ( n = 28 ) consisted of children who were referred to the unit 's outpatient clinic and did not have craniosynostosis . - pubmed
RESULTS Preoperatively , SSSv was decreased in craniosynostosis patients compared with controls ( 7.57 vs 11.31 cm / sec , p = 0.009 ) . - pubmed
Natalizumab is highly effective in the treatment of relapsing multiple sclerosis patients . - pubmed
Here we present a case of a patient who experienced a dramatic course with severe central nervous system inflammation after discontinuation of natalizumab and treatment initiation with daclizumab . - pubmed
Atypical crusted scabies in a patient with chronic liver disease caused by hepatitis B and D viruses . - pubmed
Crusted scabies is a less common variant of scabies that is highly contagious , difficult to treat and involves infestation by Sarcoptes scabiei var . - pubmed
Patients were invited to complete a questionnaire that included pain and anxiety using a visual analogue scale ( VAS ) following the testing . - pubmed
CONCLUSION : Patients transferred to a level - I trauma center are generally more severely ill at the time of admission , but mortality and mean hospital stay are similar in directly admitted and transferred patients . - pubmed
Plasmodium vivax readiness to transmit : implication for malaria eradication . - pubmed
BACKGROUND : The lack of a continuous long - term in vitro culture system for Plasmodium vivax severely limits our knowledge of pathophysiology of the most widespread malaria parasite . - pubmed
vivax human infections , we used Next Generation Sequencing data mining to unravel parasite in vivo expression profiles for P. - pubmed
Patients with ischemic heart disease are associated with poor prognosis , and their number has increased globally . - pubmed
We have outlined and thoroughly reviewed in chronological order all of the interventions from birth to adulthood necessary in the comprehensive care of the patient with cleft lip and palate , along with the effects they may or may not have on facial growth . - pubmed
Association of brucellosis to abortions in humans and domestic ruminants in Kagera ecosystem , Tanzania . - pubmed
Among aborted cases , 4 women ( out of 9 ) , 2 cows ( out of 7 ) , 2 goats ( out of 26 ) and zero sheep ( out of 11 ) were positive to brucellosis . - pubmed
Seropositivity to brucellosis was similar in aborted and non - aborted cases in humans ( p=0.08 ) and in ruminants p=0.2 ) . - pubmed
Infections to brucellosis were increased in exposed pregnant women ( OR=19 ; 95 % CI : 1.8 - 203 , p=0.01 ) and in cattle ( OR=11 ; 95 % CI : 1.3 - 88 , p=0.02 ) . - pubmed
Control of brucellosis in animals is likely to reduce the threat of abortions in humans . - pubmed
Lassa virus ( LASV ) poses a significant public health problem within the regions of Lassa fever endemicity in Western Africa . - pubmed
The impact of Lassa fever on human health , together with the limited existing countermeasures , highlights the importance of developing effective vaccines against LASV . - pubmed
rLASV(IGR / S - S ) was highly attenuated in guinea pigs , and a single subcutaneous low dose of the virus completely protected against otherwise lethal infection with LASV - WT . - pubmed
IMPORTANCE Lassa virus ( LASV ) , the causative agent of Lassa fever , infects several hundred thousand people in Western Africa , resulting in many lethal Lassa fever cases . - pubmed
We analyzed electroencephalogram ( EEG ) data from thirty - nine children ( twenty - three with , sixteen without DLD ) aged 7.17 - 15.83 years acquired during an auditory picture - word matching paradigm . - pubmed
Results : Sixty - seven children aged 3 to 36 months with an initial diagnosis of FWS were enrolled . - pubmed
Discussion : We evaluated the characteristics and clinical courses of young children with FWS presenting at a community hospital and the treatment approaches utilized by physicians . - pubmed
arabiensis to adjust their host - seeking behaviour to bite humans despite bednet protection , accounting for the maintenance of high rates of mosquito infectivity and malaria transmission . - pubmed
Bacteraemia resulting from respiratory infection was confirmed in two cases ( one each community - acquired Klebsiella pneumoniae and ventilator - associated Enterobacter cloacae ) . - pubmed
A low yield of positive respiratory cultures was identified ; Staphylococcus aureus was the most common respiratory pathogen isolated in community - acquired coinfection ( 4/24 ; 16.7 % ) , with pseudomonas and yeast identified in late - onset infection . - pubmed
Comparable rates of positive coinfection were identified in the control group of confirmed influenza infection ; clinically relevant bacteraemias ( 2/141 ; 1.4 % ) , respiratory cultures ( 10/38 ; 26.3 % ) and pneumococcal - positive antigens ( 1/19 ; 5.3 % ) were low . - pubmed
( Rosaceae ) , are usually recommended for the treatment of uterine diseases . - pubmed
( Caprifoliaceae ) could alleviate the symptoms of vulvovaginal candidiasis . - pubmed
Eighteen to fifty - year - old women with vulvovaginal candidiasis were divided into the ' ward ' and placebo groups , 46 individuals in each group . - pubmed
Results : Two weeks after medication administration , the vaginal discharge sample of patients was re - cultured ; 29 patients ( 63.045 % ) in the ' ward ' group and 6 ( 13.04 % ) patients in the placebo group had negative culture ( p < 0.001 ) . - pubmed
This finding has prompted us to explore whether such a phenomenon also occurs in diabetic obese patients . - pubmed
RESULTS : Despite subtle modifications in the oral microbiota composition , comparison of orosensory lipid perception in controls and diabetic subjects did not lead to discriminating data due to the large inter - individual variability of linoleic acid perception thresholds . - pubmed
CONCLUSIONS : Collectively , these data show that the diabetic patients with defective fatty taste detection are characterized by a specific microbiota metabolism at the circumvallate papillae levels , this occurrence seeming amplified by drugs commonly used to counteract the damaging metabolic effects of T2D. - pubmed
Accurate staging and treatment planning are imperative for precise management in Anal Cancer ( ACa ) patients . - pubmed
Background : Women living with human immunodeficiency virus ( HIV ) are more likely to develop an increased risk of invasive cervical cancer . - pubmed
A case of Schonlein - Henoch purpura induced by immune checkpoint inhibitor in a patient with metastatic melanoma . - pubmed
acidophilus ) KBL402 and KBL409 treatment in the alleviation of colitis using the in vivo dextran sodium sulfate ( DSS)-induced colitis mice model . - pubmed
Various colitis symptoms of mice , including disease activity index score [ 4.55 + - 0.99 ( P < 0.001 ) and 5.12 + - 0.94 ( P < 0.001 ) , respectively ] , colon length [ 6.18 + - 0.43 mm ( P < 0.001 ) and 6.62 + - 0.47 mm ( P < 0.001 ) , respectively ] , and colon histological score [ ( 5.33 + - 1.03 ( P < 0.001 ) and 4.00 + - 0.89 ( P < 0.01 ) , respectively ) ] , were significantly restored with L. - pubmed
Expressions of inflammation - related micro - RNAs ( miRs ) were also significantly altered in mice with L. - pubmed
Comparisons of antidotal efficacy of sodium diethyldithiocarbamate , D - penicillamine and triethylenetetramine upon acute toxicity of nickel carbonyl in rats . - pubmed
Sodium diethyldithiocarbamate , D - penicillamine , and triethylene - tetramine were administered to rats by i m injection in dosages equivalent to 0.6 times their respective LD50 values in order to compare their relative effectiveness in prevention of death caused by exposure for 15 min to inhalation of nickel carbonyl ( 1.4 or 4.2 mg Ni ( CO ) 4 / liter of air ) . - pubmed
The application of positive end - expiratory pressure ( PEEP ) as part of artificial ventilation is currently considered a basic provision to provide adequate treatment of critically ill patients in intensive care units . - pubmed
The meiotic effect of a deficiency in Drosophila melanogaster with a model for the effects of enzyme deficiency on recombination . - pubmed
At the follow - up catheterization , 39 ( 41 % ) of the patients were in improved condition and 56 patients ( 59 % ) had recurrence of symptoms , allowing for analysis of the effect of the procedure in two symptomatic patient subsets . - pubmed
The preoperative use of endoscopic ultrasound was evaluated in 74 patients with confirmed gastric cancer . - pubmed
The success rate in detecting lymph node metastasis was 50 % ( 11 of 22 patients ) ; the accuracy in diagnosing direct infiltration to the adjacent organs was 60 % ( three of five patients ) . - pubmed
A significantly lower enzymatic activity was found in atrial specimens from patients with left ventricular heart failure in comparison to the atrial fragments obtained from the patients with normal heart function . - pubmed
Verapamil enhanced in vitro chemosensitivity of a murine bladder carcinoma , FCB . - pubmed
The in vitro enhancement of chemotherapeutic efficacy by verapamil , a calcium antagonist , was assessed using FCB , a transplantable murine transitional cell carcinoma . - pubmed
Our study indicates that the use of verapamil in combination with cytotoxic agents for intravesical chemotherapy of bladder tumors may prove to be beneficial in human patients . - pubmed
The highest catalytic concentrations of the enzyme were observed in the synovial fluids of patients suffering from rheumatoid arthritis ( median value : 5.56 mU / l , 90%-range : 3.2 - 22.0 mU / l ) . - pubmed
Synovial fluids of patients with arthritis urica , however , showing a comparable high degree of inflammation , contained lower enzyme catalytic concentrations ( median value : 2.38 mU / l , 90%-range : 0.7 - 5.2 mU / l ) , which were in the range of those in osteoarthrosis ( median value : 2.50 mU / l , 90%-range : 0.8 - 4.8 mU / l ) . - pubmed
Comparison of in vitro cloning assays for drug sensitivity testing of human brain tumours . - pubmed
The MK-0787 / MK-0791 was used in 8 female patients with intrapelvic infections . - pubmed
Treatment of xerostomia in patients with primary Sjogren ' s syndrome with sulfarlem . - pubmed
Stimulated by a recent report on the favorable effect of Anetholtritione ( Sulfarlem S 25 ) on symptoms and salivary flow rate in patients with Sjogren ' s Syndrome ( SS ) , we examined the effect of Sulfarlem in an open study on 16 patients characterized by severe xerostomia . - pubmed
At the same time the patients assessed their symptoms of xerostomia on a 1 - 10 visual analogue scale . - pubmed
Side effects were abdominal discomfort and flatulence , seen in 7 patients ( 44 % ) . - pubmed
One of these patients in addition had diarrhea and nausea . - pubmed
It is concluded that Sulfarlem in a daily dose of 75 mg have no marked effect on salivation in patients with primary SS and severe xerostomia . - pubmed
In order to contribute to the knowledge and the nosography of fibroblastic rheumatism , the authors report a case occurring in 68 years old patient . - pubmed
Neurologic complications were noted in 4 % and pneumonia in 14 % of the hospitalized patients . - pubmed
Fatal outcomes were reported in 3 children ( 0.1 % ) , 2 of whom had severe congenital disabilities . - pubmed
Thirteen complications developed following one - stage lengthening of the femur , which included significant loss of length in five patients , femoral nerve palsies in four patients , three deep infections , and one nonunion . - pubmed
Transplantation of spontaneous hepatomas in C3H mice ; biological and biochemical studies . - pubmed
Twenty uncomplicated pregnancies , 10 parturients with mild and 10 parturients with severe pre - eclampsia , all with uncomplicated deliveries , were studied . - pubmed
)-induced bronchoconstriction in anaesthetized rats . - pubmed
coli strains is different than that in S. - pubmed
The decline in plasma calcium was greater in patients with osteomalacia at 90 ( P less than 0.05 ) , 120 ( P less than 0.01 ) , and 150 min ( P less than 0.01 ) . - pubmed
In osteomalacia patients the surface density of histologically detectable trabecular bone aluminum correlated directly with the percent relative osteoid volume ( P less than 0.005 ) and inversely with the maximum amino terminal parathyroid hormone response to hypocalcemia ( P less than 0.025 ) . - pubmed
These results suggest that hemodialysis patients with osteomalacia have diminished secretion of parathyroid hormone and a decreased ability to restore plasma calcium homeostasis during hypocalcemia . - pubmed
Additionally , antibody produced in response to a formalin - heat inactivated preparation was capable of reacting with antigen determinants present on the cell surface of several heterologous strains of V. - pubmed
We still need to evaluate dysphagia in patients with lymphoma by standard means , despite reports of " secondary " achalasia . - pubmed
Ultrastructural investigations of the blood vessels of thyroid in experimental acute anaphylactic shock in guinea pigs . - pubmed
Three patients with anencephalic fetuses were delivered vaginally following use of prostaglandin E2 ( PGE2 ) vaginal suppositories with minimal side effects and minimal delay until delivery , even though the cervix was unfavorable . - pubmed
The antiarrhythmic effects of amiodarone hydrochloride and flecainide acetate in patients with resistant chronic AF have been investigated separately in several small studies . - pubmed
This investigation compared amiodarone to flecainide in maintaining NSR in patients with resistant chronic AF . - pubmed
METHODS : Studies using amiodarone or flecainide in the treatment of patients with chronic AF refractory to class I antiarrhythmic drugs or sotalol hydrochloride were identified . - pubmed
The percentages of patients taking amiodarone or flecainide and remaining in NSR at 3 and 12 months were compared relative to results for quinidine , which were acquired from a meta - analysis of quinidine used as first - line therapy for AF . - pubmed
Pituitary - gonadal dysfunction in male patients with lung cancer . - pubmed
Male lung cancer patients with poor performance status have an endocrinological dysfunction shown by decreased serum levels of total and free testosterone ( AFTC ) . - pubmed
Twenty - seven patients with locally advanced non - small cell lung cancer were included . - pubmed
Review of 20 patients with glucocorticoid deficiency ( three cases also with salt loss ) associated with absent tear secretion ( 19 cases ) and achalasia of the cardia ( 15 cases ) revealed neurological abnormalities in 17 including hyper - reflexia , muscle weakness , dysarthria , and ataxia together with impaired intelligence and abnormal autonomic function , particularly postural hypotension . - pubmed
Danazol , 10 mg / kg / day ( maximum 600 mg / day ) was given in two divided doses for 14 days in 30 patients with haemophilia - A. - pubmed
Thus , lung injury after the development of tolerance to phosgene provides a unique animal model of a respiratory distress syndrome in which neutrophils are not associated with injury but rather with a protective effect . - pubmed
We are reporting the case of a 94 - year - old male patient with a 10 - year history of Parkinson ' s disease , who was admitted to our hospital with acute obstruction of esophageal passage . - pubmed
While dysphagia is commonly encountered in patients with Parkinson ' s disease , the observed succession of drug discontinuation and resolution of obstruction in this case suggests an as yet rarely described side effect of levodopa . - pubmed
This potential side effect should be included in the differential diagnosis of dysphagia in Parkinson ' s disease , especially in the case of older patients , who may exhibit an increased rate of intestinal absorption of levodopa . - pubmed
, tumor - free mice / total mice = 14 of 15 ( 93 % ) for Meth A and 7 of 15 ( 47 % ) for hepatoma MH134 . - pubmed
In this study the tilt test , in combination with isoproterenol administration , was used to investigate 44 patients with unexplained syncope . - pubmed
Treatment of three patients with systemic mastocytosis with interferon alpha-2b . - pubmed
It has been reported that the administration of interferon alpha-2b is of potential benefit in the treatment of mastocytosis based on a single patient study ( NEJM , Feb 27 , 1992 , 326(9):619 - 623 ) . - pubmed
Following this report , we administered interferon alpha-2b at a dose of 4 to 5 million units per square meter of body surface area for at least 12 months to one patient with mastocytosis with an associated hematologic disorder ( patient 1 ) , one patient with aggressive systemic mastocytosis ( patient 2 ) , and one patient with indolent mastocytosis ( patient 3 ) . - pubmed
Thus , in our study of three patients with systemic mastocytosis , treatment with interferon alpha-2b was found to be ineffective in controlling progression of disease . - pubmed
While treatment with supplemental oxygen is often essential in patients with lung disease , prolonged therapy may cause lung injury by itself . - pubmed
METHODS : Four patients ( two each with an endocrine tumor and a cystic lesion ) underwent the procedure . - pubmed
We also performed the spleen - preserving Puestow 's procedure with removal of the tail of the pancreas in a 22 - year - old male patient with familial chronic pancreatitis . - pubmed
A pancreatic fistula remained in one patient for several weeks . - pubmed
An 86 - year - old woman was admitted to our hospital with genitourinary bleeding . - pubmed
Since the initial gene - transfer clinical trial in 1989 , over 300 cancer patients have been enrolled in gene therapy trials . - pubmed
Terminal deficiencies ( TDs ) generated by the r - X1 deletion system in maize were used to physically map RFLP markers on the short arm of chromosome 2 ( 2S ) and the long arm of chromosome 6 ( 6L ) , chromosome 8 ( 8L ) , and chromosome 10 ( 10L ) . - pubmed
METHODS : A 10 - ml blood sample and six colonic biopsy specimens were obtained from 24 patients with either active ulcerative colitis or in remission and 10 patients with irritable bowel syndrome for measurement of trace elements and trace element - dependent enzymes . - pubmed
CONCLUSIONS : Patients with ulcerative colitis have altered plasma and tissue levels of trace elements and antioxidant - related enzymes . - pubmed
CONCLUSION : Differences in the mean value and in the 95 % normal range of standardized volumes of the hippocampal formation , the amygdala , and the temporal horn correspond to differences in age among healthy subjects ; therefore , age should be considered a factor in correlative research , especially in that involving patients in the early stages of Alzheimer disease . - pubmed
Helicobacter pylori leads to a chronic infection in humans that is associated with gastric inflammation and a vigorous immune response . - pubmed
Despite the humoral and cellular responses that can be detected in both human and animal models of helicobacter infection , the immune response fails to eliminate the organism . - pubmed
Results of vaccine studies in mouse models indicate that modulating the helper T cell response from a T helper cell type 1 to a T helper cell type 2 response likely is required for the prevention and elimination of helicobacter infection . - pubmed
Understanding the mechanisms by which the immune response controls bacterial infections will allow for the design of novel strategies of immune modulation and the development of vaccines for both the treatment and prevention of H pylori . - pubmed
In mature animals axons can regenerate satisfactorily through the endoneurial tubes of the root but cease growth on reaching the gliotic tissue . - pubmed
Implications for the development of human congenital heart defects are discussed . - pubmed
BACKGROUND : Minimizing the number and scope of ports used to perform laparoscopic cholecystectomy attempts to build on the improvements in postoperative pain control , rapid return to activity and work , patient satisfaction , and cosmetic result achieved by the laparoscopic method . - pubmed
A statistically significant difference was found in incisional pain between the smaller group ( 21 patients ) with two 10 - mm ports and one 5 - mm port and the larger group ( 100 patients ) with three 5 - mm ports , whether the measure was overall incisional pain ( p = 0.014 ) or a comparison based on specific ports ( p = 0.001 ) . - pubmed
The first patient developed muscle hypertonicity , jerky movements and unconsciousness after an uneventful anaesthesia with propofol , and later the same thing happened after anaesthesia with thiopentone . - pubmed
Photodynamic therapy with topical aminolevulinic acid was tested for the treatment of acne vulgaris , in an open - label prospective human study . - pubmed
Each of 22 subjects with acne on the back was treated in four sites with aminolevulinic acid plus red light , aminolevulinic acid alone , light alone , and untreated control . - pubmed
Potentially , aminolevulinic acid plus red light may be useful for some patients with acne . - pubmed
The tests were performed in 16 patients ( mean age 40.6 + /- 10.8 SD years , 10 men , 6 women ) during operative correction of their incisional hernias in the anterior abdominal wall . - pubmed
Generalized epilepsy with febrile seizures plus ( GEFS+ ) is a benign epileptic syndrome of humans . - pubmed
The use of omeprazole to alleviate stomach ulcers in swine during periods of feed withdrawal . - pubmed
Fasting for 24 h or for 48 h , resulted in more pigs developing ulcers ( 15 of 25 ) than pigs allowed free access to feed ( 1 out of 10 ) ( P = 0.01 ) . - pubmed
The presentations were ( 1 ) Sex differences in ethanol pharmacokinetics , by E. Baraona ; ( 2 ) Estrogen regulates the sensitivity to endotoxin in hepatic Kupffer cells , by K. Ikejima ; ( 3 ) Sex difference in alcohol - related organ injury , by E. Mezey ; ( 4 ) Aggravated ethanol - induced liver injury in female rats : Protection by the antiestrogen toremifene , by Harri A. Jarvelainen ; and ( 5 ) Alcohol metabolism in Asian subjects : Sex differences and flushing response , by V. A. Ramchandani . - pubmed
METHODS : Short term effects of nebulised adrenaline and saline placebo were compared in infants with moderately severe acute bronchiolitis . - pubmed
Giardia lamblia is a flagellated protozoan that infects several species including humans and is a major agent of waterborne outbreaks of diarrhea . - pubmed
Transgenic females only developed mammary cancer if treated with androgens . - pubmed
Siggaard - Andersen 's comprehensive classification of tissue hypoxia can be used as an integrative model to build coherent algorithms for diagnosing and managing neurocritical patients that are at risk of brain hypoxia due to either intracranial or extracranial conditions . - pubmed
Effects of morphine analgesia on diagnostic accuracy in Emergency Department patients with abdominal pain : a prospective , randomized trial . - pubmed
BACKGROUND : Because of concerns about masking important physical findings , there is controversy surrounding whether it is safe to provide analgesia to patients with undifferentiated abdominal pain . - pubmed
The purpose of this study was to address the effects of analgesia on the physical examination and diagnostic accuracy for patients with abdominal pain . - pubmed
MS patients were no more likely than controls to have a change in pain location ( 34.0 % versus 41.2 % , RR 0.82 , 95 % CI 0.50 - 1.36 ) . - pubmed
CONCLUSIONS : Results of this study support a practice of early provision of analgesia to patients with undifferentiated abdominal pain . - pubmed
Here we show that Cerebrolysin , an anti - dementia drug that improves the activity of daily living of Alzheimer disease ( AD ) patients , can enhance neurogenesis and spatial learning of adult female rats . - pubmed
BACKGROUND AND PURPOSE : The fetus is well known to be able to survive prolonged exposure to asphyxia with minimal injury compared with older animals . - pubmed
Recurrence or persistence of varicose veins after treatment may be charged to incomplete original evaluation of the patients ' venous insufficiency and to therapy that was not adequate because not planned on the basis of the particular kind or degree of venous incompetence in each individual case . - pubmed
METHODS : Twelve Bosnian war refugees with PTSD and 13 control subjects were studied . - pubmed
RESULTS : The PTSD patients showed no cortisol response after awakening and had lower daytime cortisol levels ( F = 14.57 , p & lt;.001 ) . - pubmed
OBJECTIVE AND METHODS : To study the effects of hormone replacement therapy on glucose metabolism , 31 obese ( body mass index & gt ; or = 27 kg / m(2 ) ) postmenopausal women were randomized to treatment with tibolone ( 2.5 mg once daily ; TIB ; n=16 ) or to oestradiol valerate ( 2 mg daily)-dydrogesterone ( 20 mg daily for 2 weeks every 3 months ; ED ; n=15 ) for 12 months . - pubmed
METHODS : Subjective sleep reports and sleep habit assessments were obtained from 25 adolescents with functional RAP and from 15 age- and gender - matched healthy volunteers , and were compared with continuous movement monitoring using the Actigraph for 7 consecutive days . - pubmed
Development of a protective index to rank effectiveness of multiple treatments within an experiment : application to a cross - protection study of several strains of Eimeria maxima and a live vaccine . - pubmed
Vaccination of chickens with live oocysts has become a more widely used method for controlling avian coccidiosis as resistance to anticoccidial medication increases . - pubmed
To confirm that rtEa4 - peptide can exhibit the same spectrum of antitumor activities in fish tumor cells , we had developed permanent single - cell clones ( RTH1B1A , RTH1B1D , RTH1B2A , and RTH1B2C ) from a rainbow trout liver tumor induced by dibenzo [ a , l ] pyrene treatment . - pubmed
CONCLUSIONS : PTS increased significantly in infants with MUL , mainly at week 2 of postnatal life , persisting high until term CA , and correlated with other abnormal EEG findings . - pubmed
During tetanic stimulation at 100 Hz the transient amplitude decays to 20 % in toad fibres and 40 % in mouse fibres . - pubmed
Bacterial infections that can be transmitted by sexual contact are usually caused by the following organisms : Neisseria gonorrhoeae , Chlamydia trachomatis , Treponema pallidum and Klebsiella granulomatis . - pubmed
CONCLUSION : Our results support the hypothesis that once - weekly oral morphine can reduce symptoms in some treatment - resistant OCD patients . - pubmed
Summary Mice homozygous for an inactivation of the interleukin-2 ( IL-2 ) gene develop a T - cell dependent colitis . - pubmed
Despite the progress made modeling MSA neuropathology in the transgenic mouse models , the molecular mechanism of how alphaSYN aggregation in oligodendrocytes causes neurodegeneration remains to be established . - pubmed
MATERIAL AND METHODS : A retrospective cohort study included 63 adults ( 40 males and 23 females ) with diagnosed brain tumors treated during 2001 and 2002 at the Department of Neurology in Novi Sad . - pubmed
Multiple metastases were estimated in 56 % of patients and solitary tumors in 44 % , without statistical significance ( 2 = 0.48 ; p & gt ; 0.05 ) . - pubmed
Acute and chronic estradiol treatments reduce memory deficits induced by transient global ischemia in female rats . - pubmed
We investigated whether long - term estradiol ( 21 - day pellets implanted 14 days prior to ischemia ) or acute estradiol ( 50 microg infused into the lateral ventricles immediately after ischemia ) attenuates ischemia - induced cell loss and improves visual and spatial working memory in ovariectomized female rats . - pubmed
Quadrigeminal cistern arachnoid cyst in a patient with Kabuki syndrome . - pubmed
Statin therapy for patients with chronic heart failure . - pubmed
METHODS : Neurosteroid levels ( allopregnanolone , pregnenolone , dehydroepiandrosterone [ DHEA ] ) were determined in postmortem PFC in 14 male subjects with AD and 15 cognitively intact male control subjects by gas chromatography / mass spectrometry preceded by high - performance liquid chromatography purification . - pubmed
RESULTS : Subjects with AD exhibit significant reductions in allopregnanolone compared with cognitively intact control subjects ( median levels = 2.50 ng / g vs. 5.59 ng / g , respectively ; p = .02 ) . - pubmed
Median DHEA levels are elevated in subjects with AD ( p = .01 ) . - pubmed
CONCLUSIONS : Subjects with AD demonstrate significant reductions in PFC allopregnanolone levels , a finding that may be relevant to neuropathological disease stage severity . - pubmed
This strain can grow at 50 degrees C but not at 51 degrees C , a temperature at which wild - type B. - pubmed
Pravastatin enhances beneficial effects of olmesartan on vascular injury of salt - sensitive hypertensive rats , via pleiotropic effects . - pubmed
RESULTS : The modified ALTK procedure effectively treated a patient with moderate keratoconus with a best - corrected visual acuity of 20/80 , despite rigid gas - permeable contact lenses . - pubmed
This report describes a 76 - year - old female patient with pseudomyxoma peritonei who presented with lower abdominal pain and bilateral femoral masses . - pubmed
HHV-8 DNA was detected in 14 of the 17 Kaposi ' s sarcoma tissue samples and both of the primary effusion lymphoma cell lines . - pubmed
Low - level laser therapy for zymosan - induced arthritis in rats : Importance of illumination time . - pubmed
METHODS : We tested LLLT on rats that had zymosan injected into their knee joints to induce inflammatory arthritis . - pubmed
The availability of a simple , sensitive , and rapid test using whole blood to facilitate processing and to reduce the turnaround time could improve the management of patients presenting with chest pain . - pubmed
High tobacco use among the less educated and under privileged affects them in multiple ways : ( i ) Tobacco users in such households , because of their nicotine addiction , prefer spending a disproportionate amount of their meager income on tobacco products , often curtailing essential expenditures for food , healthcare and education for the family . - pubmed
( iii ) Premature death caused by tobacco use in this under- privileged section often takes away the major wage earner in the family , plunging it into even more hardship . - pubmed
Tobacco use , education and health in a human population are inter - related in ways that make sufferings and deaths caused by tobacco use even more tragic than normally realized . - pubmed
The seasonality of human cryptosporidiosis in New Zealand . - pubmed
While consensus and guidelines on therapeutic management in infancy and childhood are available , data regarding the treatment of adults with CAH are scarce . - pubmed
This review highlights the issues that need to be addressed when caring for the adult CAH patient . - pubmed
Use of the folinic acid/5 - fluorouracil / irinotecan ( FOLFIRI 1 ) regimen in elderly patients as a first - line treatment for metastatic colorectal cancer : a Phase II study . - pubmed
BACKGROUND : The aim of this study was to evaluate the effects of a combination of folinic acid , 5 - fluorouracil ( 5FU ) and irinotecan ( FOLFIRI 1 ) administered every 2 weeks in a population of elderly subjects with advanced colorectal cancer . - pubmed
PATIENTS AND METHODS : Patients with metastatic colorectal cancer included in this study were aged at least 70 years , with a performance status of 0/1 , without geriatric syndrome and without previous palliative chemotherapy . - pubmed
All PHPT patients became normocalcaemic following successful neck exploration . - pubmed
OBJECTIVE : Patients on buprenorphine maintenance for opioid dependence often abuse its additional doses over and above the maintenance dose . - pubmed
DESIGN AND SETTING : This was an interventional study , carried out in an in - patient setting in a tertiary care national drug dependence treatment center . - pubmed
[ Initiation modes of spontaneous monomorphic ventricular tachycardia in patients with Chagas heart disease ] . - pubmed
INTRODUCTION AND OBJECTIVES : We sought to demonstrate the mode of spontaneous onset of sustained monomorphic ventricular tachycardia in patients with Chagas ' cardiomyopathy . - pubmed
METHODS : We studied 222 stored electrograms in 14 patients with Chagas cardiomyopathy and spontaneous monomorphic ventricular tachycardia treated with a cardioverter defibrillator . - pubmed
Production of nicotinic acid from Saccharomyces cerevisiae in exponential growth on glucose was found to be growth associated , and in the stationary and decline phase was found to be death associated . - pubmed
Primary cultures of human urothelial cells for genotoxicity testing . - pubmed
Cell cultures of primary human urothelial cells may be used for in vitro testing of cytotoxic or genotoxic effects . - pubmed
Our results are in line with functional imaging studies in patients with schizophrenia , which also showed a differential activation in lateral prefrontal areas . - pubmed
However , at surgery , with a 125 - microg dose , these patients had a discontinuous layer of vitreous present on the retinal surface resulting from the induction of an anomalous PVD in the form of vitreoschisis . - pubmed
METHODS : Twenty - five patients with primary or secondary open - angle glaucoma and at high risk for postoperative cicatrization underwent deep sclerectomy and were randomly distributed to the two treatment arms . - pubmed
METHODS : Patients with anastomotic leakage after abdominothoracic oesophagectomy treated by endoscopic insertion of self - expanding plastic stents between 2001 and 2007 were studied . - pubmed
These mice displayed no tooth eruption or tooth root formation . - pubmed
Adult mutant mice developed odontoma - like proliferations near the proximal ends of the incisors . - pubmed
CLINICAL RELEVANCE : These data suggest that cerebral magnetic resonance imaging may be recommended in the clinical treatment of patients with apparently isolated ARA , even when neurological symptoms or signs are lacking . - pubmed
MATERIAL / METHODS : Fresh tissue samples were obtained from 28 patients ( ages 26 to 81 years ) with primary colorectal adenocarcinoma and corresponding normal tissues . - pubmed
Visuospatial working memory deficits in remitted patients with bipolar disorder : susceptibility to the effects of GABAergic agonists . - pubmed
METHODS : A total of 32 remitted BPD patients and 39 healthy controls undertook parametric VSWM tasks and assessments for selective attention , sustained attention , psychomotor speed , mental flexibility , and Wechsler Adult Intelligence Scale - III full IQ . - pubmed
RESULTS : Remitted BPD patients showed more pronounced performance declines in VSWM performances as WM loads increased , indicating inefficient VSWM processing . - pubmed
CONCLUSIONS : Remitted BPD patients had WM - load - dependent VSWM processing deficits after controlling for neurocognitive performances . - pubmed
Prophylaxis of embolic events with idraparinux over an 18 - month period in patients with atrial fibrillation was as effective as international normalized ratio - adjusted warfarin but induced more major bleeding complications . - pubmed
Currently idrabiotaparinux once weekly 3.5 mg subcutaneous is being investigated in clinical trials for the prevention of recurrent events in patients with acute VTE and atrial fibrillation . - pubmed
Computed tomographic pulmonary angiography for diagnosis of invasive mold diseases in patients with hematological malignancies . - pubmed
BACKGROUND : Invasive mold diseases ( IMDs ) of the lung remain a challenge for immunocompromised patients . - pubmed
METHODS : To explore the diagnostic utility of computed tomographic pulmonary angiography ( CTPA ) for detecting angioinvasive patterns of pulmonary infection , we performed a single - center , prospective , nonrandomized trial involving 36 patients with hematological malignancies who had clinical suspicion of IMD , as defined by European Organization for Research and Treatment of Cancer / Mycosis Study Group diagnostic criteria . - pubmed
In 15 of 24 patients with a final diagnosis of possible IMD , CTPA findings were negative for 14 patients and were positive for 1 patient , who had septic emboli associated with Staphylococcus aureus bacteremia . - pubmed
CONCLUSIONS : We conclude that CTPA appears to be a promising tool to exclude the diagnosis of IMD in high - risk patients without specific findings on HRCT scans , and it is most useful in the presence of well - circumscribed lesions in which there is suspicion for IMD . - pubmed
Our results show the key role of immune subversion in effective human infection by small bacterial populations . - pubmed
Nonconvulsive status epilepticus : the encephalopathic pediatric patient . - pubmed
Recent prospective pediatric studies focus on critically ill children and show wide variability in the frequency of NCSE . - pubmed
METHODS : Medical records from patients aged 3 months to 21 years were identified either by ( 1 ) searching a clinical EEG database ( n = 18 ) or ( 2 ) consecutive inpatient EEG referrals for NCSE over an 8 - month period ( n = 57 ) . - pubmed
NCSE was identified in 26 patients ( 35 % ) and in 8 of 57 ( 14 % ) patients referred for possible NCSE . - pubmed
A witnessed clinical seizure was observed in 24 of 26 ( 92 % ) patients with NCSE . - pubmed
Acute cortical neuroimaging abnormalities were significantly more frequent in patients with NCSE . - pubmed
All but 1 patient with NCSE had electrographic or electroclinical seizures within the first hour of monitoring . - pubmed
Children with acute encephalopathy should undergo continuous EEG . - pubmed
We present a case in which a patient was treated with covered stent implantation for acute bleeding from the superior mesenteric artery following pancreatic resection , radiation , and embolization of a hepatic artery pseudoaneurysm . - pubmed
Effect of patient sex on white matter alterations in unilateral medial temporal lobe epilepsy with hippocampal sclerosis assessed by diffusion tensor imaging . - pubmed
BACKGROUND AND PURPOSE : Studies shows ictal behavior and symptoms are affected by patient sex in temporal lobe epilepsy . - pubmed
The purpose of our study was to determine whether alterations in the WM as assessed by DTI display different patterns in male and female patients with unilateral HS . - pubmed
MATERIALS AND METHODS : Patients with unilateral HS were categorized as women with right HS ( n=12 ) , men with right HS ( n=10 ) , women with left HS ( n=12 ) , and men with left HS ( n=10 ) . - pubmed
In patients with right HS , the ipsilateral cingulum , uncinate fasciculus , internal and external capsules , and right acoustic radiation were involved extensively in women . - pubmed
BACKGROUND : Moniliophthora perniciosa ( Stahel ) Aime & amp ; Phillips - Mora is the causal agent of witches ' broom disease ( WBD ) in cacao ( Theobroma cacao ) . - pubmed
Injury of the CA1 subregion induced by a single injection of kainic acid ( 1 x KA ) in juvenile animals ( P20 ) is attenuated in animals with two prior sustained neonatal seizures on P6 and P9 . - pubmed
CONCLUSION : Scanning of stomach specimens using electron microscope revealed that the mice treated with standard and synthetic derivatives had no injury observed in stomach mucosa , which is identical to that of the control animal . - pubmed
Neural pathway interference by retained acupuncture : a functional MRI study of a dog model of Parkinson ' s disease . - pubmed
RESULTS AND DISCUSSION : Standard veterinary neurological examination was performed on dogs with MPTP - induced PD . - pubmed
A homogeneous grade similar to human PD patients was evident in all dogs . - pubmed
The study provides evidence of the potential clinical applications of retained acupuncture at ST 36 for rehabilitation therapy of PD patients . - pubmed
Here , we report a rare presentation of metastatic breast cancer patient with bone marrow metastases , who was successfully treated with trastuzumab combined chemotherapy . - pubmed
Physicians should be careful in treating bone marrow metastases in breast cancer , since patients can show improved marrow function after chemotherapy and long - lasting survival is possible . - pubmed
The pathogenesis of dengue virus infection remains poorly understood , mainly due to the lack of a suitable animal model that can recapitulate the cardinal features of human dengue diseases . - pubmed
There are four dengue viral serotypes and each one of them is capable of causing severe dengue . - pubmed
We treated 60 patients with unilateral ulnar neuropathy at the elbow , employing both techniques . - pubmed
Six months postoperative we found no differences in treatment effect on pain and disability scores between both groups , but both techniques resulted in an early postoperative relief of symptoms and good patient satisfaction . - pubmed
Considering the zoonotic potential of tick - borne disease ( TBD ) agents and the fact that dogs may act as sentinels for human infection , the aim of the present study was to determine the seroprevalence of TBD agents and risk factors for exposure in two different canine populations from Parana State , Southern Brazil . - pubmed
Dogs from UA showed a higher percentage of tick infestation ( p = 0.0135 ) and were highly associated with seropositivity to E. - pubmed
The proton beam radiosurgery was performed to 65 patients with brain AVM since December , 2001 till February , 2012 , in Joint Institute for Nuclear Research , Dubna , Russia . - pubmed
The radiosurgery was resulted in full obliteration of AVM in 23 from remaining 46 ( 50 % ) patients . - pubmed
There was full obliteration in 46.6 % of patients with volume of AVM 10 - 24.9 cc ; and this rate is significantly more than for photon radiosurgery of same size brain AVM . - pubmed
Only one patients suffered hemorrhage from partially obliterated AVM . - pubmed
There were delayed radiation toxicity in 5 patients in 12 months after treatment : in 4 patients , these reactions were assessed as 2 according to RTOG scale and were dissipated in 1 month after commencement of corticosteroid treatment . - pubmed
There was radiation necrosis in one patient , and it was relieved in 12 months after several courses of dehydration and corticosteroid therapy . - pubmed
Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer ' s disease . - pubmed
Inhaled particles and gases ( in particular tobacco smoke ) induce chronic inflammation of the airways accompanied by a not fully reversible airflow limitation . - pubmed
OBJECTIVE : To examine differences in disease progression and nature of tumor invasion that may lead to more accurate expectations of tumor behavior and improved management options for plasmacytoid variant ( PCV ) histology urothelial bladder cancer patients . - pubmed
Carcinoma in situ on the luminal margin was noted for all cases , except in 5 of the 8 PCV patients with + UM , in whom retrograde longitudinal invasion along the subserosal and adventitia was noted . - pubmed
Remove isolated vomiting as an automatic indication for computed tomography in children with head injury . - pubmed
Unexpectedly , the Ex3 - del+/- mice are not susceptible to CPVT . - pubmed
Model to predict the survival benefit of radiation for patients with rhabdomyosarcoma after surgery : a population - based study . - pubmed
Patients with resection of rhabdomyosarcoma between 1990 and 2010 were derived from the Surveillance , Epidemiology and End Results database . - pubmed
CONCLUSION : The available literature sources do n't show that hormone replacement therapy for premenopausal women worsens the prognosis of the underlying disease after treatment of gynecological cancer . - pubmed
Other complications included a permanent neurologic deficit in 1 patient ( 5 % ) , transient paraplegia in 4 patients ( 20 % ) , and 3 patients had respiratory complications ( 15 % ) . - pubmed
Stent - related complications were identified in 4 patients ( 20 % ) , including 3 type I endoleaks , none of which were at zone 0 . - pubmed
Spinal cord stimulation in patients with painful diabetic neuropathy : a multicentre randomized clinical trial . - pubmed
To our knowledge , ours is the first multicentre randomized controlled trial investigating the effectiveness of SCS in patients with PDN . - pubmed
Sixty patients with PDN in the lower extremities refractory to conventional medical therapy were enrolled and followed for 6 months . - pubmed
In patients with refractory painful diabetic neuropathy , spinal cord stimulation therapy significantly reduced pain and improved quality of life . - pubmed
Autoantibody status and histological variables influence biochemical response to treatment and long - term outcomes in Japanese patients with primary biliary cirrhosis . - pubmed
Associations between various factors ( including age , sex , autoantibody status and histological variables at baseline ) , biochemical response to treatment and long - term outcomes were evaluated in 164 Japanese PBC patients . - pubmed
CONCLUSION : Biochemical response to treatment at 2 years , which is influenced by autoantibody status and histological variables at baseline , can predict long - term outcomes in Japanese patients with PBC . - pubmed
RESULTS : Data from 384 people , 213 with diabetes , were analysed . - pubmed
The mean ( + -sd ) age of the people with diabetes was 58.6 ( + -8.2 ) years and in the control subjects it was 56.1 ( + -8.6 ) years . - pubmed
Cardiac autonomic neuropathy was present in 51 of the 138 people evaluated ( 37.0 % ; 95 % CI 28.8 - 45.1 ) . - pubmed
We report a case of a middle aged man who presented to us with the complaints of documented body temperature fluctuations since two months followed gradually by hoarseness of voice , sexual dysfunction and syncope . - pubmed
Patient 's work up for secondary causes of hypopituitarism was negative . - pubmed
Patient was suspected as a case of autoimmune hypophysitis and was immediately treated with prednisolone along with hormone replacement . - pubmed
BACKGROUND : The objective of this study was to determine the efficacy and safety of locoregional therapy ( LRT ) combined with arsenic trioxide ( As2 O3 ) treatment in primary hepatocellular carcinoma ( HCC ) patients . - pubmed
METHODS : One hundred twenty - five primary HCC patients were recruited for a randomized controlled study . - pubmed
There were fewer patients with extrahepatic metastases in group A versus group B ( group A , 6 cases or 9.84 % [ 95 % CI , 2.36%-17.31 % ] ; group B , 12 cases or 18.75 % [ 95 % CI , 9.19%-28.31 % ] ) . - pubmed
CONCLUSIONS : LRT combined with As2 O3 treatment prevents extrahepatic metastasis and prolongs the survival time for primary HCC patients . - pubmed
Sarcocystis calchasi encephalitis in a rock pigeon . - pubmed
A rock pigeon ( Columba livia ) caught in Akihabara , Tokyo , showed neurological symptoms , such as head tilt and circling . - pubmed
vaginalis ) causes trichomoniasis , a reproductive tract infection , in humans . - pubmed
In the Western hemisphere , at least five mammarenaviruses cause human viral hemorrhagic fevers with high case fatality rates . - pubmed
Junin virus ( JUNV ) is the only hemorrhagic fever virus for which transfusion of survivor immune plasma that contains neutralizing antibodies ( " passive immunity " ) is an established treatment . - pubmed
We propose that viral receptor - binding site accessibility explains the success of passive immunity against JUNV and that this functionally conserved epitope is a potential target for therapeutics and vaccines to limit infection by all New World hemorrhagic fever mammarenaviruses . - pubmed
[ Efficacy of percutaneous coronary intervention in patients with chronic ischaemic heart disease ] . - pubmed
BACKGROUND AND PURPOSE : Patients with large vessel occlusion strokes ( LVOS ) may be better served by direct transfer to endovascular capable centers avoiding hazardous delays between primary and comprehensive stroke centers . - pubmed
Hyperglycemia and hypertension are considered to be two of the leading risk factors for vascular complications in diabetic patients . - pubmed
However , few pharmacologic agents could provide a combinational therapy for controlling hyperglycemia and blood pressure in diabetic patients at the same time . - pubmed
BACKGROUND : Like Duchenne muscular dystrophy ( DMD ) , the Golden Retriever Muscular Dystrophy ( GRMD ) dog model of DMD is characterized by muscle necrosis , progressive paralysis , and pseudohypertrophy in specific skeletal muscles . - pubmed
This severe GRMD phenotype includes moderate atrophy of the biceps femoris ( BF ) as compared to unaffected normal dogs , while the long digital extensor ( LDE ) , which functions to flex the tibiotarsal joint and serves as a digital extensor , undergoes the most pronounced atrophy . - pubmed
CONCLUSIONS : The identification of elevated BF oleic acid ( a long - chain fatty acid ) is consistent with recent microarray studies identifying altered lipid metabolism genes , while alterations in arginine and proline metabolism are consistent with recent studies identifying elevated L - arginine in DMD patient sera as a biomarker of disease . - pubmed
We describe two new species of the genus Xanthomonas , represented by yellow mucoid bacterial strains isolated from diseased leaves of watercress ( Nasturtium officinale ) produced in Florida , USA . - pubmed
Multilocus sequence analysis and whole genome - wide comparisons of the average nucleotide identity ( ANI ) of genomes of two strains from watercress showed that these are distinct and share less than 95 % ANI with all other known species ; the non - pathogenic strain WHRI 8848 is close to Xanthomonascassavae ( ANI of 93.72 % ) whilst the pathogenic strain WHRI 8853 is close to a large clade of species that includes Xanthomonasvesicatoria ( ANI & lt;=90.25 % ) . - pubmed
Based on these results , we propose that both strains represent new Xanthomonas species named Xanthomonas floridensis sp . - pubmed
( type strain WHRI 8848 = ATCC TSD-60 = ICMP 21312 = LMG 29665 = NCPPB 4601 ) and Xanthomonas nasturtii sp . - pubmed
( type strain WHRI 8853 = ATCC TSD-61 = ICMP 21313 = LMG 29666 = NCPPB 4600 ) , respectively . - pubmed
Ileocolic resection is associated with increased susceptibility to injury in a murine model of colitis . - pubmed
These surgical - induced altered immune - microbial interactions in the intestine may contribute to disease recurrence at the surgical anastomosis site following ileocolic resections in patients with Crohn ' s disease . - pubmed
Human papillomavirus ( HPV ) is the most commonly sexually transmitted infection in the world and the primary cause of cervical cancer . - pubmed
Studies focused on in vitro cellular toxicity of the formulations and their single components using A549 human lung cells showed no obvious cytotoxicity for the formulations containing lecithin and PEG 32 stearate . - pubmed
The effect of metabolic syndrome on recurrence in patients who had undergone surgery for carpal tunnel syndrome . - pubmed
OBJECTIVES : This study aims to investigate whether or not metabolic syndrome ( MS ) affects recurrence in patients who had undergone surgery for carpal tunnel syndrome ( CTS ) . - pubmed
Patients were examined clinically and demographically for the presence of MS . - pubmed
Diagnoses of recurrence were established using electromyography in patients with clinical CTS and Tinel and/or Phalen test positivity . - pubmed
CONCLUSION : Our study indicated that MS affected recurrence in patients who had undergone CTS surgery . - pubmed
WHAT IS KNOWN ALREADY : Knowledge on long - term sequelae for development and health of children born following PGS is lacking . - pubmed
Proteomic profiling of integral membrane proteins associated to pathogenicity in Vibrio parahaemolyticus strains . - pubmed
Vibrio parahaemolyticus has been recognized as the causal agent of early mortality syndrome and is currently considered an emerging shrimp disease causing losses of millions in the aquaculture industry . - pubmed
parahaemolyticus and an ATCC strain that is pathogenic for humans were obtained by a sequential extraction method and subjected to relative quantification and identification by isobaric Tags for Relative and Absolute Quantitation . - pubmed
The ability to engineer primary human B cells to differentiate into long - lived plasma cells and secrete a de novo protein may allow the creation of novel plasma cell therapies for protein deficiency diseases and other clinical applications . - pubmed
Mycophenolate mofetil treatment in a patient with recurrent lymphocytic hypophysitis . - pubmed
We report here the case of a 58 - year - old patient with LHP who developed panhypopituitarism and bitemporal hemianopia . - pubmed
Continuous renal replacement therapy is a standard treatment in critically ill patients with acute kidney injury . - pubmed
We investigated whether a new super high - flux hemofilter provides effective and sustained middle molecule clearance during citrate - anticoagulated continuous venovenous hemodialysis for up to 72 h. We included 14 critically ill patients with AKI - KDIGO - III in a prospective observational trial . - pubmed
This new hemofilter may improve blood purification in critically ill patients with AKI . - pubmed
Fifty - one patients underwent an ES prior to developing primary CBDS ( 8.9 % ) . - pubmed
Thyroid hormone status in patients with severe selenium deficiency . - pubmed
In this study , to clarify the association between Se and thyroid hormone status , we investigated the thyroid hormone levels in patients with severe Se deficiency ( & lt ; 2 microg / dl ) . - pubmed
However , epidemiologic studies on the relationship between endogenous levels of melatonin and hypertension in humans are limited . - pubmed
We examined the association of quartile levels of 6 - sulfatoxymelatonin ( aMT6s ) in first morning urines with prevalent and incident hypertension in 777 postmenopausal women who were originally part of a case - control study of breast cancer nested in the Women 's Health Initiative Observational Study . - pubmed
Aberrant protein glycosylation events are hallmarks of human diseases such as cancer and infectious diseases . - pubmed
METHODS : Using microarray , we performed the transcriptome - wide lncRNA and mRNAs expression profile of peripheral blood mononuclear cells ( PBMCs ) of 93 CAD patients and 48 healthy controls . - pubmed
qRT - PCR was used to validate selected lncRNAs in 412 CAD patients and 295 healthy controls . - pubmed
Two novel lncRNA biomarkers , ENST00000444488.1 and uc010yfd.1 , together with CAD risk factors , had the better performance for discrimination of CAD patients from healthy controls , and ENST00000444488.1 could diagnose acute myocardial infarction ( AMI ) patients . - pubmed
Frequency and coinfection between genotypes of human papillomavirus in a population of asymptomatic women in northern Peru . - pubmed
The occurrence observed in this case implies that patients with TCM should be monitored closely for arrhythmias , and , if such a condition is identified , planning for permanent pacemaker implantation should be started early enough to avoid recurrent life - threatening episodes . - pubmed
Pharmacogenomics and personalized medicine will soon be part of CF patient care . - pubmed
Growing the phenotype of chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids ( CLIPPERS ) in children . - pubmed
Outcome of two patients with bilateral nephroblastomatosis / Wilms tumour treated with an add - on 13 - cis retinoic acid therapy - Case report . - pubmed
We added 13 - cis retinoic acid to the standard chemotherapy with vincristine and actinomycin - D in two patients with bilateral nephrogenic rests / nephroblastomatosis . - pubmed
Patient 1 also had a history of Wilms tumour . - pubmed
46 ( patient 1 ) and 81 ( patient 2 ) months after end of treatment , both patients show stable conditions with no signs of relapse or progressive disease . - pubmed
Our observation supports further investigation of retinoic acid in patients with nephrogenic rests and nephroblastomatosis . - pubmed
We evaluated patient and allograft outcomes in pediatric liver transplant recipients of DCD livers . - pubmed
CONCLUSION : Pediatric liver transplant recipients of DCD allografts have comparable patient and allograft survival when compared to DBD allograft recipients . - pubmed
MATERIALS AND METHODS : Plasma was sampled from 10 healthy subjects and 10 patients with diabetes . - pubmed
METHODS : Dogs were randomly divided into the sham - operated group ( SO ; n = 6 ) , AMI group ( AMI ; n = 8) and the group undergoing LOMLSPV ablation ahead of AMI ( LOMD+AMI ; n = 8) . - pubmed
To determine the true therapeutic effects of LOTUS , we used a more clinically relevant contusive SCI model in female transgenic mice . - pubmed
Protective Effects of Nicorandil on Cardiac Function and Left Ventricular Remodeling in a Rat Model of Ischemic Heart Failure . - pubmed
Moreover , the composite fiber was able to be stitched onto a highly stretchable elastic bandage using a sewing machine to produce a wearable strain sensor for the detection of diverse human motions . - pubmed
RESULTS : The majority of the patients were pubescent ( 31.8 % ) males ( 56.8 % ) , and the main aetiology of the burn was flammable substances ( 75 % ) . - pubmed
To identify bacterial factors required for transmission , we conducted a high - throughput genetic screen with a transposon sequencing ( Tn - seq ) library of a pneumococcal strain in a ferret transmission model . - pubmed
Here , we report novel pathological defects in skeletal muscle fibres of mouse models and patients with NM : irregular spacing and morphology of nuclei ; disrupted nuclear envelope ; altered chromatin arrangement ; and disorganisation of the cortical cytoskeleton . - pubmed
At day 75 , rats who had developed NO2 - induced emphysema were then divided into sodium hydrosulfide ( NaHS ) administrated group , placebo ( NaCl ) group and spontaneous recovery group for about one month ( days 76 - 105 ) ; Pulmonary function ( PF ) and hematological and biochemical indices were measured at days 14 , 45 , 75 , and 105 . - pubmed
CONCLUSIONS : NO2 exposure causes emphysema and a decline in PF in rats . - pubmed
Hearing Preservation With the Use of Flex20 and Flex24 Electrodes in Patients With Partial Deafness . - pubmed
OBJECTIVE : We investigated the impact of depressed mood ( dysphoria ) and loss of interest or pleasure ( anhedonia)on the risk of dementia in cognitively - normal elderly individuals . - pubmed
METHODS : This study included 2,685 cognitively - normal elderly individuals who completed the baseline and 4 - year follow - up assessments of the Korean Longitudinal Study on Cognitive Aging and Dementia . - pubmed
CONCLUSION : Anhedonia , but not dysphoria , is a risk factor of dementia in cognitively - normal elderly individuals . - pubmed
In children with cancer , the issues related to the quality of life are becoming increasingly important together with the improvement of survival rates . - pubmed
Ultrastructural markers of tissue endometrial receptivity in patients with recurrent implantation failure . - pubmed
The scanning electron microscopy of the endometrial surface epithelium during the ' implantation window ' was performed in 119 patients with uterine factor of infertility or recurrent miscarriage due to endometrial hypoplasia . - pubmed
Epiploic appendagitis as unusual cause of acute abdominal pain : Clinical and radiologic features of 7 patients . - pubmed
Characterization of Circulating Clostridium difficile Strains , Host Response and Intestinal Microbiome in Hospitalized Children With Diarrhea . - pubmed
BACKGROUND : Clostridium difficile is capable of causing severe enterocolitis in adults . - pubmed
CONCLUSIONS : Children with diarrhea regularly carried toxigenic and non - toxigenic strains of C. - pubmed
The feed additive Aviax 5 % , containing the active substance semduramicin sodium , an ionophore anticoccidial , is intended to control coccidiosis in chickens for fattening at a dose of 20 - 25 mg / kg complete feed . - pubmed
Aviax 5 % at a minimum dose of 20 mg / kg feed has the potential to effectively control coccidiosis in chickens for fattening . - pubmed
Breaking down walls : a qualitative evaluation of perceived emergency department delays for patients transferred with ST - elevation myocardial infarction . - pubmed
While metformin has been shown to have pleotropic effects on glucose metabolism , there is a general consensus that the major glucose lowering effect in patients with type 2 diabetes is mostly mediated through inhibition of hepatic gluconeogenesis . - pubmed
A network approach to investigating the key microbes and stability of gut microbial communities in a mouse neuropathic pain model . - pubmed
We collected 66 fecal samples over 2 weeks ( three mice and 11 time points in spared nerve injury - induced neuropathic pain and Sham groups ) . - pubmed
RESULTS : Here we show that spared nerve injury - induced neuropathic pain alters gut microbial diversity in mice . - pubmed
Oscillospira , which was classified as a low - abundance and core microbe , was identified as the key microbe in the Sham group , whereas Staphylococcus , classified as a rare and non - core microbe , was identified as the key microbe in the spared nerve injury - induced neuropathic pain group . - pubmed
Further improvement in glycemic control after switching from exenatide two times per day to exenatide once - weekly autoinjected suspension in patients with type 2 diabetes : 52 - week results from the DURATION - NEO-1 study . - pubmed
RESEARCH DESIGN AND METHODS : In this phase III open - label study , adults with type 2 diabetes were randomized to receive exenatide QWS - AI ( 2 mg ) or exenatide two times per day ( 5 mcg for 4 weeks , followed by 10 mcg ) for 28 weeks . - pubmed
CASE REPORT A 54 - year - old man with recent COVID-19 exposure presented with fever , cough , dyspnea , and syncope and was found to be in hypoxic respiratory failure requiring supplemental oxygen . - pubmed
A bedside echocardiogram can provide valuable information in patients with suspected high - risk pulmonary embolism and hemodynamic instability . - pubmed
METHODS : This paper presents a novel technique called Smart Sepsis Predictor ( SSP ) to predict sepsis onset in patients admitted to an intensive care unit ( ICU ) . - pubmed
METHODS : Single - institution prospective cohort study of patients requiring craniotomy for brain tumor resection operated using an electromagnetic navigation system ( AxiEM , Medtronic ) . - pubmed
CONCLUSION : The information provided by the IONM in intracranial neurosurgery patients whilst also using electromagnetic navigation systems is reliable for monitoring , mapping , and detecting intraoperative complications , provided that the appropriate software filters and tools are applied . - pubmed
We aimed to assess outcomes in stroke patients treated with different endovascular procedures versus direct MT alone for isolated M2 - MCA occlusion . - pubmed
We conducted a cohort study on data from 506 stroke patients with isolated M2 - MCA occlusion who were enrolled in the Italian Registry of Endovascular Treatment in Acute Stroke cohort . - pubmed
In stroke patients with isolated M2 - MCA occlusion , MT plus IAT was associated with better outcomes as compared with direct MT alone . - pubmed
[ Thrombocyte kinetics in children with idiopathic thrombocytopenic purpura after splenectomy ] . - pubmed
Therefore a study was carried out in our laboratory on the cellular characteristics of the epididymal depot of the Fisher 344 strain of rats through virtually the entire life - span . - pubmed
During the chronic infection , toxins of P. - pubmed
Fifty - six femoral non infected anastomotic false aneurysms ( FAAs ) were observed in 49 patients admitted to the Institute of Vascular Surgery , University of Milan , from 1975 to 1988 ; in 6 patients they were bilateral . - pubmed
A history of hypertension was present in 30 % of the patients . - pubmed
In 5 patients aneurysm resection was carried out on both sides . - pubmed
Lung torsion : survival of a patient whose hemorrhagic infarcted lung remained in situ after detorsion . - pubmed
To test the hypothesis that chloral hydrate can cause direct hyperbilirubinemia ( DHB ) in the newborn , two retrospective analyses of the medical records of patients admitted to a neonatal intensive care unit during an 18 - month period were conducted . - pubmed
The anticancer properties of these esters have been compared with those of DFMO and MAP as a function of the dose , the route of administration , and the stage of the lewis lung carcinoma development in mice . - pubmed
shortly after cell inoculation at one - fifth the dose of DFMO , prolonged the survival of mice - bearing leukemia to the same extent as DFMO and MAP . - pubmed
When administered orally to leukemia - bearing mice the two esters were equipotent at prolonging survival . - pubmed
, maximum prolongation of the mice survival ( 79 % ) occurring at 0.5 g / kg methyl ester every 12 h. The two esters achieve at one - sixth to one - twelfth the dose , antitumor effects similar to DFMO in the Lewis lung carcinoma model , the ethyl ester being slightly , but not significantly , more effective than the methyl ester when administered orally . - pubmed
A patient with acute myeloid leukemia ( AML ) who developed probable aspergillosis of the lung underwent partial lobectomy prior to allogeneic bone marrow transplantation ( BMT ) . - pubmed
Histopathologic alterations in the decidua in human spontaneous abortion : loss of cells with large cytoplasmic granules . - pubmed
Since the presence of suppressor cell activity in murine decidua correlates with the success of pregnancy and since this suppression is associated with small lymphocytes with cytoplasmic granules , the observations made using human placental bed biopsy material suggest that a possible suppressor cell deficiency might occur in the early stages of spontaneous abortion in human females . - pubmed
This rapidly released antigenic / allergenic component may play an important role in the initiation of immunologic responses in patients with allergic bronchopulmonary aspergillosis . - pubmed
[ Phytolysin in the complex treatment of patients with chronic suppurative otitis media ] . - pubmed
A prospective blinded randomized study was carried out to determine the effect of antepartum administration of dexamethasone on the incidence of respiratory distress syndrome in 250 patients with gestations between 28 and 33 weeks complicated by premature rupture of membranes . - pubmed
The incidence of respiratory distress syndrome was not lowered by the length of rupture of membranes in the 124 untreated patients . - pubmed
Repair of osteochondral defects in articular weightbearing areas in the rabbit 's knee . - pubmed
( 2 ) The percentage of ABG - bound plasma aldosterone was found to vary with the seasonal change in temperature and the hepatic function of CF patients . - pubmed
The authors report another case of successful endocavitary electrocautery in a young woman with Wolff - Parkinson - White syndrome . - pubmed
[ Identification of animal strains of Clostridium welchii by the agglutination test . - pubmed
Congenitally abnormal vision in Siamese cats . - pubmed
The effect of topical vitamin A on papillomas and intraepithelial carcinomas induced in hamster cheek pouches with 9,10 - dimethyl-1,2 - benzanthracene . - pubmed
[ Changes in the oxygen deficiency tolerance in man induced by psychopharmaca ] . - pubmed
Sixty - six patients with advanced head and neck cancer 57 of whom had failed to respond to prior irradiation , were treated according to two protocols . - pubmed
Group I consisted of 41 patients in relapse who received a monthly combination of bleomycin , vincristin , methotrexate and hydroxyuera . - pubmed
Before any chemotherapy , 62 p. 100 of the relapsing patients gave negative responses to delayed hypersensitivity skin tests to recall antigens . - pubmed
Survival of patients with metastatic recurrence was significantly higher than survival in patients with local recurrence . - pubmed
Uterine infections in three mares following repeated uterine manipulations and antibiotic therapy were caused by Aspergillus fumigatus in two cases and Candida albicans in the third . - pubmed
The aim of this prospective work was to analyze the results of 3 methods of esophageal pH recording ( i. e. short - term pH test , 3 - hr postprandial recordings , and 12 - hr nocturnal pH recording ) in 47 patients with suspected gastroesophageal reflux . - pubmed
According to the results of nocturnal pH recordings , 32 patients were considered to suffer from acid gastroesophageal reflux and 15 patients as being free of reflux . - pubmed
Because of the absence of lamina propria in the biopsy specimens obtained at endoscopy , histological diagnosis of esophagitis was possible in only 35 patients ( 74 p. 100 ) . - pubmed
Acute toxicity of hydrazine hydrate to the fathead minnow ( Pimephales promelas ) and daphnid ( Daphnia pulex ) . - pubmed
In the experience of one of the authors with outpatient cataract and intraocular lens surgery , 66.7 percent of outpatients achieved visual acuity of 20/40 or better and 33.3 percent of inpatients achieved visual acuity of 20/40 or better . - pubmed
Rats treated with TET bromide ( 30 mg / liter ) in their drinking water for 3 weeks showed a profound decrease in acoustic startle reflex amplitudes which was apparent prior to overt neuromuscular weakness and subsequent hindlimb paralysis . - pubmed
Serological markers for hepatitis B virus in male homosexuals demonstrated a high prevalence of past and present infection . - pubmed
Preliminary report on mellituria in phenylketonuric children : modification in the excretion of glucose and pentoses . - pubmed
Colonic adenocarcinoma with cutaneous metastasis in a dog . - pubmed
METHODS : Ninety consecutive patients ( 50 males , 40 females ) , 80 percent of whom had second or third degree hemorrhoids , had ambulatory hemorrhoidectomy performed with a CO2 laser in the left lateral Sims position under local anesthesia and intravenous sedation . - pubmed
RESULTS : One patient with polycythemia vera was admitted subsequently for secondary hemorrhage . - pubmed
For comparison we also studied 66 patients with benign lung diseases and nine with pleural mesothelioma . - pubmed
In patients with SCLC , high levels of all markers except SCC were found when the disease was extensive . - pubmed
Increased brain QUIN levels have also been shown in acute hyperammonemic rats . - pubmed
The NH4Ac administration induced coma in all of the PCS rats 20 - 25 min after the challenge , and this coma was resolved within 60 - 75 min . - pubmed
The capacity of inhibiting the carrageenan - induced edema in the rat paw and the writhes induced by acetic acid in mice were evaluated , as well as the ulcerogenic action in rats . - pubmed
The last patient also had type II PGA syndrome . - pubmed
In vivo secretory responses of submandibular glands in streptozotocin - diabetic rats to sympathetic and parasympathetic nerve stimulation . - pubmed
Submandibular gland responses to sympathetic and parasympathetic nerve stimulation were studied in streptozotocin - diabetic rats . - pubmed
In 6 - month diabetic rats flow rate remained increased , but protein concentration and total protein output were reduced . - pubmed
[ Renal tubular acidosis in children ] . - pubmed
METHODS : To assess the feasibility of therapeutic fetal heart block , we developed a technique of intrauterine cryosurgical ablation of fetal atrioventricular node without the need for cardiac bypass in 8 fetal lambs . - pubmed
Patients were excluded if they had prior peritoneal lavage , bladder or bowel injury , or low hematocrit values . - pubmed
Only 6 ( 14 % ) of 42 patients had mean attenuation values greater than 40 H , whereas 4 ( 10 % ) of 42 patients had mean attenuation values less than 20 H. The remaining 32 patients ( 76 % ) had mean attenuation values between 21 and 40 H. Patients with hepatic lacerations showed no significant difference ( p = .3509 ) in attenuation between perihepatic fluid and the remainder of intraperitoneal fluid . - pubmed
Heterogeneous T cell receptor V beta gene repertoire in murine interstitial nephritis . - pubmed
In vivo studies in which UCN-01 was administered by continuous intraperitoneal infusion in subcutaneous and intracranial intraparenchymal nude rat models demonstrated significant activity against U-87 glioma xenografts at dose levels that were well tolerated . - pubmed
Urine autoantibodies that bound to normal human bladder epithelial cells were present in 8 of 14 IC specimens ( from 6 of 9 IC patients ) as compared to 3 of 23 control specimens ( from 2 of 17 control patients ) . - pubmed
Three IBDV strains were examined after propagation in different hosts . - pubmed
The RE profiles of the STC and MD IBDV strains did not change after propagation in either BGM-70 cell culture or chicken bursas , whereas the Del - A RE profile changed at the Sau3AI site after adaptation to BGM-70 cell culture . - pubmed
We describe an approach which combines proteome analysis ( mapping of expressed proteins isolated by two - dimensional polyacrylamide gel electrophoresis to the genome ) with genetic manipulations to study the complex pattern of protein regulation occurring in Escherichia coli in response to sulfate starvation . - pubmed
We have previously described the upregulation of eight spots on two - dimensional ( 2 - D ) gels in response to sulfate starvation and the assignment of six of these to entries in the E. - pubmed
METHODS : Thirty - seven eyes of 37 normal - tension glaucoma ( NTG ) patients were examined . - pubmed
CONCLUSIONS : These data indicate that the absence of residual pancreatic beta - cell function in patients with insulin - dependent diabetes mellitus is associated with neuroendocrine dysfunction in the regulation of circadian TSH secretion , which is not reversible after restoration of good glycaemic control . - pubmed
The position and length of the steroid - dependent hypersensitive region in the mouse mammary tumor virus long terminal repeat are invariant despite multiple nucleosome B frames . - pubmed
Patients with early Alzheimer ' s disease ( AD ) were compared to normal controls and patients with early vascular dementia ( VaD ) on their naming errors using the Boston Naming Test ( H. Goodglass & E. Kaplan , 1983 ) . - pubmed
Interestingly , our monoclonal antibodies also reacted with two other Plasmodium species ( Plasmodium berghei NKK173 strain and P. - pubmed
Lentigo maligna ( LM ) is well known as an irregularly pigmented macular lesion usually presenting on the sun - damaged head and neck of older patients . - pubmed
The purified virus contains all of the genetic information required for its infection cycle as it readily replicated in cowpea protoplasts and systemically infected Vicia faba seedlings that were biolistically inoculated using gold particles coated with intact virions or viral DNA . - pubmed
The bombarded plants not only developed the typical disease syndrome , thus indicating that FBNYV is the sole causal agent of the disease , but also served as a source from which the virus was readily acquired and transmitted by A. - pubmed
Early alterations in gene expression and cell morphology in a mouse model of Huntington ' s disease . - pubmed
Several mouse models for Huntington ' s disease ( HD ) have been produced to date . - pubmed
We decided to analyze the morphology of striatum and hippocampus from a mouse transgenic line obtained by microinjection of exon 1 from the HD gene after introduction of a very high number of CAG repeat units . - pubmed
DESIGN / METHODS : We report a series of 2 normal newborn patients who had a large prenatal unilateral intracranial cyst diagnosed by PSG in the 10 years between July of 1989 and 1999 at a rural community hospital . - pubmed
We studied 18 eligible patients with low - grade and 21 patients with intermediate- or high - grade NHL . - pubmed
One patient in the intermediate / high - grade NHL group developed a partial response lasting longer than 15 months ( 5 % ; 95 % CI 0 - 24 % ) . - pubmed
Cardiac toxicity , gastrointestinal ulceration and nasal congestion due to rhuIL-4 were not prominent toxicities in our patients . - pubmed
Our previously treated NHL patients tolerated s.c . - pubmed
Genetically obese , leptin - deficient ob / ob mice are models for nonalcoholic fatty liver disease ( NAFLD ) , a type of liver disease that is strongly associated with obesity and type 2 diabetes . - pubmed
Similar to obese , diabetic patients , ob / ob mice have an increased incidence of HCC . - pubmed
However , unlike humans with NAFLD , they rarely , if ever , develop cirrhosis spontaneously . - pubmed
To determine whether the noncirrhotic livers of ob / ob mice with NAFLD exhibit hepatocyte hyperplasia , parameters of proliferation and apoptosis were compared in adult ob / ob mice and their healthy litter mates . - pubmed
Thus , liver hyperplasia is evident at the earliest stage of NAFLD in ob / ob mice , which supports the concept that obesity - related metabolic abnormalities , rather than cirrhosis , initiate the hepatic neoplastic process during obesity . - pubmed
Concerning HSV- and VZV - prophylaxis there are almost no differences between recommendations of the german society and the american institutions , however recommendations for preventing CMV - disease and CMV - recurrence do differ considerably . - pubmed
VZV vaccination or CMV prevention , should be studied in oncology and infectious diseases working groups to define consensus in the near future . - pubmed
RESULTS : Animal models of abnormal gastrointestinal motility were established in mice and rats . - pubmed
This report describes the early magnetic resonance imaging ( MRI ) findings and long - term follow - up results of albendazole treatment in a 16 - year - old girl with primary hydatid disease of the femur diagnosed incidentally during the course of a post - traumatic knee infection . - pubmed
[ Tuberculosis in elderly patients ] . - pubmed
Medicinal treatment of intractable dyspnea in terminally ill patients . - pubmed
We report a very rare case of a simultaneous rupture of the right patellar and left quadriceps tendon in an otherwise healthy 37 - year - old patient , who jumped off a kickboard . - pubmed
A series of 42 patients with 45 rectal tumors ( 9 adenomas , 36 adenocarcinomas ) who underwent gasless VTEM between 1993 and 2000 were studied prospectively . - pubmed
During the median follow - up length of 73.3 months , no patient developed tumor recurrence in the gasless VTEM group , whereas one patient did in the control group . - pubmed
The influence of steatosis on the outcome of orthotopic liver transplantation ( OLT ) was evaluated in 860 liver transplantations carried out in 784 patients from October 1990 to August 2001 . - pubmed
Macrovesicular steatosis affecting 15 % or more of the hepatocytes was the only variable independently associated with shorter patient and graft survival ( P=0.0012 and 0.0028 ) . - pubmed
A significantly worse prognosis was to be expected if & gt;15 % macrovesicular steatosis was associated with a total ischemia time & gt;10 h ( P=0.048 ) , or donor age & gt;65 years ( P=0.016 ) or with HCV - positive recipients ( P=0.0014 ) . - pubmed
The risk of graft non - function or patient loss after OLT rises if macrovesicular steatosis & gt;15 % is associated with long ischemia time , high donor age , or HCV positivity in recipients . - pubmed
Competition among Bradyrhizobium strains for nodulation of green gram ( Vigna radiata ): use of dark - nodule strain . - pubmed
The competitiveness of dual - strain inoculum of Bradyrhizobium strains S24 and GR4 was demonstrated for nodulation of green gram ( Vigna radiata ) . - pubmed
The dark - brown nodule - phenotype could be useful in evaluating nodulation competitiveness of " cowpea miscellany " bradyrhizobia in soil where dark - brown nodule - forming strains are not indigenous . - pubmed
Also at this time , a phase II trial in children suffering from GHIS was initiated . - pubmed
The title compounds 2a - j and 3a - j were screened in vivo using carrageenan - induced rat paw edema model . - pubmed
Histoplasma capsulatum variety duboisii isolated in Japan from an HIV - infected Ugandan patient . - pubmed
A strain of Histoplasma capsulatum var . - pubmed
We report on a case of periosteal osteoblastoma arising from the posterior surface of the right distal femur in a 17 - year - old man . - pubmed
Conversion to laparotomy occurred in three patients based on intraoperative findings of suspected primary ovarian cancer and for technical reasons in one patient . - pubmed
Overall , metastatic breast cancer was diagnosed in 21 ( 68 % ) of 31 patients , including two patients with occult metastases undergoing BSO for hormonal ablation . - pubmed
Primary ovarian cancer was found in 3 ( 10 % ) of 31 patients , and 7 ( 22 % ) of 31 patients had benign findings . - pubmed
RESULTS : Our survey suggested analgesic nephropathy in 47 of 1400 patients ( 3.3 % ) , 3 - fold higher than the EDTA database estimate for Hungary . - pubmed
The results demonstrate on the one hand , very high indices of cardiovascular risk ( smoking , hypertension , dyslipidaemia and albuminuria ) and on the other , good quality primary health care providing good detection and follow up management of type 2 diabetic patients . - pubmed
Effect of ethanol extract of Piper betle Linn leaf on healing of NSAID - induced experimental ulcer -- a novel role of free radical scavenging action . - pubmed
betle at a dose of 150 mg / kg body weight daily for 10 days , after induction of peptic ulcer by NSAID in albino rats , produced significant healing effect . - pubmed
Salmonella enterica serotype Enteritidis ( SE ) is a common cause of foodborne illness in the United States . - pubmed
Update on lymphatic mapping and sentinel node biopsy in the management of patients with melanocytic tumours . - pubmed
AIMS : To communicate best practices for sentinel lymph node evaluation and assessment of prognosis for patients with melanoma . - pubmed
METHODS : Description and justification of approaches derive from experience with management of more than 2000 melanoma patients evaluated by lymphatic mapping and sentinel node biopsy ( LMSNB ) . - pubmed
Continuous renal replacement therapy ( CRRT ) is used to treat renal failure in children . - pubmed
Children with high fluid overload ( & gt;10 % ) at CRRT initiation were at 3.02 times greater risk of mortality than those with low or no fluid overload [ 95 % confidence interval ( CI ) 1.50 - 6.10 , P=0.002 ] . - pubmed
OBJECTIVE : To determine the incidence and risk factors for post - ICU mortality in patients with infection . - pubmed
PATIENTS : All 1,872 patients discharged alive from the ICU over a 1 - year period were screened for infection at ICU admission and daily throughout the ICU stay . - pubmed
Campylobacter jejuni is a leading cause of bacterial gastroenteritis in the developed world . - pubmed
It is concluded that soil water was not equally available to Fraxinus mandshurica seedlings in the test ranges of soil water potential , and significant water stress could occur when the soil water potential was lower than -40 kPa . - pubmed
The aim of this study was to investigate over a 3 - year period the connection between homocysteine ( Hcy ) levels and development of Alzheimer ' s disease ( AD ) in patients with mild cognitive impairment ( MCI ) . - pubmed
Thirty - three percent of men with Hcy levels > 20 micromol / l converted to AD . - pubmed
The corresponding figure for men with Hcy levels 20 - 17 micromol / l was 50 % , whereas none of the 18 men with Hcy levels < 17 micromol / l converted to AD . - pubmed
There was also a statistically significant difference between the percentage of women with Hcy levels > 16 micromol / l who converted to AD ( 45 % ) as compared to those with Hcy levels < 16 micromol / l who converted ( 21 % ) . - pubmed
However , our findings tentatively suggest a possible protective effect of low / normal Hcy levels on dementia conversion in MCI patients . - pubmed
During the more difficult three - operand task , individuals with TS demonstrated significantly less activation in frontal , parietal and subcortical regions than controls . - pubmed
Individuals with TS demonstrate activation differences in fronto - parietal areas during arithmetic tasks compared with controls . - pubmed
Past accidental poisonings in humans show that exposure to high levels of either contaminant is associated with motor impairments , including alterations in cerebellar functions such as balance and coordination . - pubmed
Epidemiological studies of lower level exposures suggest some neuromotor impairment in exposed children , but the majority of these studies have focused on cognitive endpoints rather than examining a full - range of motor function . - pubmed
Clinical and experimental findings in humans and animals with chemotherapy - induced peripheral neuropathy . - pubmed
The pilot trial included 11 patients with acute - on - chronic liver failure and concomitant renal failure . - pubmed
Thus , Prometheus might be a new therapeutic option in patients with severe hepatorenal syndrome . - pubmed
Antiproliferation and apoptosis induced by C - glycosides in human leukemia cancer cells . - pubmed
The treatment of mice with clenbuterol ( 2 mg / kg body wt for 30 days ) resulted in skeletal muscle hypertrophy , more common amongst fast - twitch glycolytic fibres / muscle , with increase in body mass and a parallel rise in muscle mass to body mass ratio . - pubmed
Measurement of fibre diameters in soleus ( rich in slow - twitch oxidative fibres ) , ALD or anterior latissimus dorsi ( with a predominance of fast - twitch glycolytic fibres ) and gastrocnemius ( a mixed - type of muscle ) from clenbuterol - treated mice for 30 days revealed noticeable increase in the per cent population of narrow slow - twitch fibre and a corresponding decline in white - type or fast - twitch glycolytic fibres in gastrocnemius and ALD . - pubmed
Th2 - dominant immune response , possibly caused by concurrent bacterial or parasitic infections , could explain , in part , the lower risk of H. - pubmed
BACKGROUND : Nonrandomized studies suggest that atrioventricular ( AV ) junction ablation and pacemaker implantation may improve quality of life , ejection fraction , and exercise tolerance in patients with symptomatic drug - refractory atrial fibrillation . - pubmed
[ Protective effect of melatonin and sodium thiosulphate on histopathology and ultrastructure of the kidney in rats with acute paraquat poisoning ] . - pubmed
Actions of N - arachidonyl - glycine in a rat neuropathic pain model . - pubmed
In the present study we examined the effect of NAGly in a rat model of neuropathic pain . - pubmed
METHODS : A panel of 64 serum biomarkers was analyzed in sera of patients with stages I - III endometrial cancer and age - matched healthy women , utilizing a multiplex xMAP bead - based immunoassay . - pubmed
Anatomic distribution and electrophysiologic properties of accessory atrioventricular pathways in dogs . - pubmed
ANIMALS : 10 dogs with tachyarrhythmias associated with an AP . - pubmed
PROCEDURES : Each dog underwent electrophysiologic testing to determine the inducibility of documented and undocumented arrhythmias and to identify location , conduction properties , and antegrade and retrograde effective refractory periods of the APs . - pubmed
RESULTS : 15 APs were identified ; 7 dogs each had a single AP , and 3 had multiple APs . - pubmed
All documented tachyarrhythmias could be induced during electrophysiologic testing ; atrial fibrillation was also inducible in 2 dogs . - pubmed
CONCLUSIONS AND CLINICAL RELEVANCE : Results suggested that in dogs , most APs are right - sided , had unidirectional retrograde conduction , and are associated with various arrhythmias , including orthodromic atrioventricular reciprocating tachycardia and atrial fibrillation without evidence of pre - excitation . - pubmed
PATIENTS : Twelve men with IHH ( age 40.8 + /- 2.8 yr ) were studied : 1 ) on hormone replacement with normal T levels and 2 ) 2 wk after discontinuing therapy . - pubmed
Seven strains of Listeria monocytogenes and 8 of their derivative strains were screened for their capacity to form biofilms . - pubmed
The strains of L. - pubmed
Aspergillosis was identified in 10 cases ( 3.6 % ) and diagnosis was confirmed when clinical symptoms were associated with identification of Aspergillus sp . - pubmed
Incidence of Aspergillosis considerably decreased from 6.9 % to 0.6 % when liposomal amphotericin B was introduced as prophylaxis in high - risk patients . - pubmed
Two patients ( 20 % ) died because of Aspergillosis Liposomal Amphotericin B prophylaxis in high - risk children decreases the incidence of Aspergillus infection . - pubmed
OBJECTIVE : To know relative dose intensity ( RDI ) in patients with breast cancer treated with chemotherapy . - pubmed
Esophageal hypersensitivity is one of the most common causes of noncardiac chest pain in patients . - pubmed
We conclude that enhanced responses of thoracic spinal neurons to ED by the chemically challenged esophagus may provide a possible pathophysiological basis for visceral hypersensitivity in patients with gastroesophageal reflux and/or esophagitis . - pubmed
Aldohexose malabsorption in preterm pigs is directly related to the severity of necrotizing enterocolitis . - pubmed
Therefore , a preterm pig model that spontaneously develops NEC was used to investigate the relationship between severity of NEC lesions and galactose absorption in vivo and carrier - mediated glucose absorption by intact mid small intestine . - pubmed
Pigs were killed when symptoms of NEC were observed or after 36 - 40 h of enteral nutrition . - pubmed
Though the serological test showed no positive antibody titer against Rickettsia japonica , Rickettsia japonica was isoleted from blood culture , to confirm Japanese spotted fever , Japanese spotted fever is generaly a curative disease with early diagnosis and minocycline . - pubmed
Evolutionary relationships between sporadic and epidemic strains of healthcare - associated methicillin - resistant Staphylococcus aureus . - pubmed
No significant drug influence was observed on the anxiety - related mice behavior in the light / dark test . - pubmed
IBS was subsequently compared with histologic findings of the respective tissue in 10 patients who underwent endarterectomy . - pubmed
These data suggest that these high - drinking lines may represent an unexpectedly appropriate complex model of how multiple factors may contribute to the genesis of human alcoholism . - pubmed
OBJECTIVE : To evaluate the relationship between renal activity and quality of life ( QOL ) in patients with systemic lupus erythematosus ( SLE ) . - pubmed
METHODS : Three hundred eighty - six patients completed annual Medical Outcomes Study Short Form-36 questionnaires and physicians completed the SLE Disease Activity Index and Systemic Lupus International Collaborating Clinics / American College of Rheumatology Damage Index . - pubmed
Single nucleotide polymorphisms of cytokine genes are associated with fibrosis of the intrahepatic bile duct wall in human clonorchiasis . - pubmed
BACKGROUND : Seizures are poorly controlled in many people with epilepsy , despite current antiepileptic treatments . - pubmed
OBJECTIVES : To determine the effectiveness and safety of traditional Chinese medicine in people with epilepsy . - pubmed
METHODS : One hundred and seven consecutive patients with 110 wide - necked or fusiform intracranial aneurysms were treated with the Neuroform stent - assisted coiling . - pubmed
Angiography follow - up was obtained in 45.8 % ( 49/107 patients ; 51/110 aneurysms ; average follow - up time : 37.2 months ) . - pubmed
One patient with in - stent stenosis and one with penetrating artery occlusion occurred as delayed complications . - pubmed
Recently , the Arabidopsis - Colletotrichum higginsianum ( causal agent of anthracnose ) system has emerged as a seminal paradigm for deciphering the infection biology underlying fungus - plant interactions . - pubmed
Trypan blue and aniline blue staining were employed to scan the infection structures of the hemibiotrophic fungus C. - pubmed
BACKGROUND : Individuals with medial knee osteoarthritis often present with varus knee alignment and ambulate with increased knee adduction moments . - pubmed
Second , as only few population - based studies are available , the prevalence of oxidative stress among CKD patients remains undetermined . - pubmed
Finally , while two recent pilot studies have demonstrated that treatment of CKD patients with antioxidants is able to reduce cardiovascular events , information related to the pharmacokinetic characteristics of antioxidants , as well as their efficacy to prevent oxidative stress , is still limited in this patient group . - pubmed
METHODS : Thirty subjects with clinical diagnosis of primary open angle glaucoma and 30 healthy subjects were recruited . - pubmed
Semaphorins of the SemaIV family are expressed in neurons and decreased in brains from patients with Alzheimer ' s disease ( AD ) . - pubmed
The significant antimalarial potential was revealed by a 100 % cure rate of malaria in mice with one administration of 100 mg / kg of 1 . - pubmed
Ventricular function and all - cause mortality in chronic kidney disease patients with angiographic coronary artery disease . - pubmed
Traditional and nontraditional risk factors , hypertension , fluid overloading and anemia can lead to myocardial ischemia , chamber hypertrophy and dilatation , and low left ventricular ejection fraction ( LVEF ) in CKD patients . - pubmed
The angiographic feature , ventriculographic LVEF and its relationship to all - cause mortality are unclear in patients with different stages of CKD who are not yet on dialysis . - pubmed
METHODS : This retrospective study involved 980 CKD patients with suspected myocardial ischemia who underwent coronary angiography from 1995 to 2004 . - pubmed
RESULTS : Of the CKD patients , 445 ( 45.4 % ) had angiographic CAD . - pubmed
Low LVEF was the only independent significant prognostic factor in CKD patients with angiographic CAD ( HR=0.957 ; 95 % CI , 0.918 - 0.996 ) . - pubmed
Community - acquired pneumonia ( CAP ) is a common and potentially serious illness with significant human and economic costs to society . - pubmed
Pregabalin and edema in young women suffering from premenstrual syndrome . - pubmed
METHODS : From December 2005 to December 2008 , 54 patients with cervical syndrome ( 34 males and 20 females , the age was from 39 to 69 years with an average of 50.5 ) were treated with single level Bryan prosthetic cervical disc replacement . - pubmed
RESULTS : The pain symptom and neurological function of all 54 patients were improved obviously . - pubmed
PHPT is asymptomatic for 80 % of patients and responsible for a decrease in bone mineral density particularly in women . - pubmed
METHODS : We performed a prospective analysis of patients with PHPT in order to evaluate the prevalence of vitamin D deficiency . - pubmed
RESULTS : 75 patients with PHPT were identified : 38 patients with vitamin D deficiency but only 22 patients could be followed ( G1 ) . - pubmed
Basophils are important effector cells , which contribute to protection against helminths and execute proinflammatory effector function during allergic inflammation . - pubmed
Silent ischemia normalized for coronary collateral function in patients with and without diabetes mellitus . - pubmed
It appears to be spreading to new areas with several countries reporting their first human cases of CCHF disease within the past 10 years . - pubmed
It is capable of detecting strains from all 7 groups of CCHF , including the AP92 strain that until recently represented a lineage of strains that were not associated with human disease . - pubmed
BACKGROUND : Tranexamic acid ( TXA ) has been shown to reduce blood loss in surgical patients and the risk of death in patients with traumatic bleeding , with no apparent increase in vascular occlusive events . - pubmed
OBJECTIVE : The Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage Intracranial Bleeding Study ( CRASH-2 IBS ) was conducted to quantify the effect of an early short course of TXA on intracranial haemorrhage and new focal cerebral ischaemic lesions in patients with TBI . - pubmed
Patients eligible for inclusion in the CRASH-2 IBS fulfilled the inclusion criteria for the CRASH-2 trial , and also had TBI [ Glasgow Coma Scale score of & lt;= 14 and a brain computerised tomography ( CT ) scan compatible with TBI ] . - pubmed
CONCLUSIONS : This was the first randomised controlled study to evaluate the effect of TXA in TBI patients and it found that neither moderate benefits nor moderate harmful effects can be excluded . - pubmed
However , although uncertainty remains , our analyses suggest that TXA administration might improve outcome in TBI patients and provide grounds for evaluating this hypothesis in future research . - pubmed
This article will give a short overview on the most common animal models and a comprehensive overview on markers for sepsis in animal models and clinical studies . - pubmed
Patient charts were reviewed regarding cardiac arrest variables and treatment data of all patients from 1993 to 2010 . - pubmed
The first recorded ECG rhythm showed pulseless electric activity in 23 ( 42 % ) , ventricular fibrillation in 21 ( 38 % ) and asystole in 11 ( 20 % ) patients . - pubmed
Cardiac arrest occurred out - of - hospital in 33 ( 60 % ) patients . - pubmed
In this seemingly desperate patient population after prolonged cardiac arrest , we observed a high survival rate of 15 % . - pubmed
Linear growth and neurodevelopmental outcome of children with congenital hypothyroidism detected by neonatal screening : A controlled study . - pubmed
INTRODUCTION : Different growth and neuro - developmental outcomes have been associated with different doses of thyroxine given to infants with congenital hypothyroidism ( CH ) . - pubmed
RESULTS : Birth weight , length , and head circumference of patients ( 3.21 + - 0.43 kg , 50.5 + - 3.21 cm and 34.1 + - 1.5 cm , respectively ) did not differ than those for 10,560 normal newborns with normal thyroid function ( 3.19 + - 0.59 kg , 50.5 + - 2.2 cm and 34.2 + - 1.7 cm ) . - pubmed
In this cross - sectional study , genomic DNA of 41 patients with permanent CH due to thyroid dyshormonogenesis was extracted using the salting out method . - pubmed
To explore the mechanisms of Salmonella desiccation resistance , we studied the transcriptomic responses in Salmonella Tennessee ( Tennessee ) , using Salmonella Typhimurium LT2 ( LT2 ) , a strain weakly resistant to desiccation , as a reference strain . - pubmed
In this study , we evaluated the clinical outcomes of this treatment approach in 75 patients with LT . - pubmed
Thus , induction chemotherapy followed by HCT has the potential for long - term disease control in select patients with LT preceded by a MPN . - pubmed
Consecutive eligible patients ( n = 181 ) were divided into 3 groups : patients with CAE , those with newly diagnosed coronary artery disease ( CAD ) , and those with a normal coronary angiogram . - pubmed
The N / L ratio and MPV were significantly higher in patients in both CAE and CAD groups compared to those in the control group ( P & lt ; .01 ) . - pubmed
PURPOSE : The purpose of this study was to examine the influencing factors of postoperative pain among children undergoing elective surgery . - pubmed
RESULTS : Children experienced moderate preoperative anxiety and postoperative pain . - pubmed
Boys reported less postoperative pain than girls . - pubmed
PRACTICE IMPLICATIONS : Effective strategies for assessing and managing children 's preoperative anxiety are needed to achieve an optimal postoperative pain management outcome . - pubmed
The universe is made up of 60 overweight / obese children and adolescents aged between 10 and 18 years . - pubmed
Vaccination for smallpox in humans and rinderpest in cattle was the basis for disease eradication , and recent progress in polio eradication is promising . - pubmed
Then , chronic administrations of HD0471953 were performed to evaluate the efficacy on various diabetic rodent models . - pubmed
The results suggest that HD0471953 may be a potentially promising anti - hyperglycemic agent for the treatment of patients with type 2 diabetes mellitus . - pubmed
CKD patients are at high risk not only for end - stage renal disease , but also for cardiovascular disease , infection , malnutrition , and other comorbid conditions frequently associated with the elderly population . - pubmed
Sleep fragmentation and increased periodic limb movements are more common in children with nocturnal enuresis . - pubmed
METHODS : Paediatricians assessed NE parameters in children referred to an enuresis clinic . - pubmed
RESULTS : The study group comprised 67 children with proven NE ( 50 boys and 17 girls between six and 16 years : 11.1 + - 2.8 SD ) . - pubmed
Children with NE had a higher incidence of periodic limb movements associated with cortical arousals in their sleep . - pubmed
CONCLUSION : Children with NE displayed higher sleep fragmentation and periodic limb movements in sleep than the control children with a possible sleep disorder without NE . - pubmed
Urinary polycyclic aromatic hydrocarbon metabolites and attention / deficit hyperactivity disorder , learning disability , and special education in U.S. children aged 6 to 15 . - pubmed
The balance was measured by Berg Balance Scale ( BBS ) , Postural Assessment Scale for Stroke Patients ( PASS ) , and Functional Reach Test ( FRT ) . - pubmed
Understanding this dysbiosis is challenging because of the extraordinary complexity of the gut ecosystem and the tremendous variability between healthy individuals in the taxa that make up the human microbiome . - pubmed
PURPOSE : Postpneumonectomy empyema ( PPE ) is a possible complication after a pneumonectomy in patients with lung cancer . - pubmed
Recurrence of PPE within 6 months of initial PPE resolution occurred in 28 % of patients . - pubmed
Crocin ( a carotenoid isolated from saffron ) , has protective effects against DZN cardiotoxicity . - pubmed
METHODS : Rats were divided into 7 groups : corn oil ( control ) , DZN ( 15 mg / kg / day , gavage ) , crocin ( 12.5 , 25 , 50 mg / kg / day , i. p. ) plus DZN , vitamin E ( 200 IU / kg , i. p. , 3 days a week ) plus DZN and crocin ( 50 mg / kg / day , i. p. ) . - pubmed
Prostatic urethral lift improves urinary symptoms and flow while preserving sexual function for men with benign prostatic hyperplasia : a systematic review and meta - analysis . - pubmed
Repair of acute type A aortic dissection in comatose patients . - pubmed
The DNA G+C content of strain JC234 T was 54.3 mol % . - pubmed
The type strain is JC234 T ( = KCTC 42071 T = LMG 28200 T ) . - pubmed
SUBJECTS : Two hundred thirty adult male Sprague - Dawley rats weighing 280 - 320 g. INTERVENTIONS : Subarachnoid hemorrhage was induced in rats by endovascular perforation . - pubmed
Nussenzweig and colleagues evaluate genomic instability and germinal center derived lymphomagenesis in mice infected with Plasmodium to recreate some of the hallmark characteristics of Burkitt lymphoma , a form of cancer more common in parts of Africa where malaria is endemic . - pubmed
We describe a patient with acute kidney injury due to glomerular bleeding and tubular injury related to severe thrombocytopaenia , who was subsequently found to have thin basement membrane disease . - pubmed
CASE PRESENTATION : A 56 year old man presented with macroscopic haematuria , acute kidney injury and a platelet count of 35 x 10(9)/L , in the absence of anticoagulation . - pubmed
At 9 months , the patient progressed to Stage 5 chronic kidney disease with the development of gross renal atrophy . - pubmed
CONCLUSION : Recurrent macroscopic haematuria may be a risk factor for progressive renal injury in patients with thin basement membrane . - pubmed
In the absence of anticoagulation , severe thrombocytopaenia may be a risk factor for heavy glomerular bleeding and acute kidney injury in these patients . - pubmed
Restricted temporal access to food and anorexia in mice : Microstructure of eating within feeding opportunities . - pubmed
Intake and body weight were recorded in a closed economy as male and female C57BL/6 mice progressed through either fixed interval ( FI ) or fixed unit price ( FUP ) schedules of cost for 20 - mg food pellets . - pubmed
In the FI protocol , mice maintained adequate food intake and body weight through the study , even though at the highest FI ( 50 - s ) they spent the entire 40 - min FOs engaged in eating at or near the maximum rate allowed by the schedule . - pubmed
We discuss the role of effort or time in FUP - induced anorexia , and suggest this murine model may emulate some aspects of human anorexia nervosa better than current activity - based protocols . - pubmed
Osteosarcoma is the most frequent primary malignant bone tumor that occurs in children and adolescents . - pubmed
The present study aimed to identify novel therapeutic strategies for osteosarcoma , by assessing the antitumor activity of the cannabinoid WIN-55,212 - 2 and its combined effect with adriamycin ( ADM ) against the MG-63 human osteosarcoma cell line . - pubmed
Over - drainage and persistent shunt - dependency in patients with idiopathic intracranial hypertension treated with shunts and bariatric surgery . - pubmed
METHODS : The study cohort includes 13 patients with IIH that underwent shunt surgery for treatment of the IIH - related symptoms . - pubmed
CONCLUSIONS : Patients with IIH that undergo shunt surgery and BS ( not concomitantly ) may suffer from OD symptoms , necessitating multiple shunt revisions , and valve upgrades . - pubmed
Resident workers and soldiers were age - matched with unfamiliar worker stimulus animals as intruders , and encounters were videorecorded and scored for aggressive behaviors . - pubmed
These data suggest that in naked mole - rats OT promotes prosocial behaviors rather than aggression and that even within subordinates status exerts robust effects on brain and behavior . - pubmed
Final components of the TB / HIV electronic medical records system include : patient demographics ; anthropometric measurements ; laboratory samples and results ; HIV testing ; WHO clinical staging ; TB diagnosis ; family planning ; clinical review ; and drug dispensing . - pubmed
RESULTS : Our experience suggests that an electronic medical records system can improve patient management , enhance integration of TB / HIV services , and improve provider decision - making . - pubmed
CASE DESCRIPTION : A 68 - year - old man presented with cerebral infarction due to an artery - to - artery embolism from the right cervical ICA stenosis . - pubmed
BACKGROUND : Snakebite incidence in southwestern China is mainly attributed to one of the several venomous snakes found in the country , the white - lipped green pit viper Trimeresurus albolabris . - pubmed
Resolution of left ventricular postinfarction thrombi in patients undergoing percutaneous coronary intervention using rivaroxaban in addition to dual antiplatelet therapy . - pubmed
Left ventricular ( LV ) thrombus is usually seen in situations with reduced LV function , and is mostly seen in patients with large anterior ST - elevation myocardial infarction ( MI ) . - pubmed
Most embolic events , in patients with LV thrombus formation , occur within the first 3 - 4 months , thus the recommendations regarding the duration of anticoagulant therapy . - pubmed
Novel oral anticoagulants were found to be either non - inferior or superior compared with warfarin in prevention of thromboembolism in patients with non - valvular atrial fibrillation . - pubmed
Here , we report on the dissolution of LV apical thrombus in 3 patients with anterior ST - elevation MI receiving dual antiplatelet therapy and rivaroxaban on a reduced dose for 3 months . - pubmed
STUDY DESIGN : We retrospectively reviewed 158 children with precursor B - cell type ALL who were followed up for & gt;2 years . - pubmed
Intensive evaluations for hematologic malignancies may be unnecessary in children who complain of limb pain without any definite cause , unless they also present with accompanying leukemic symptoms . - pubmed
Comparing samples from femoral heads harvested from 11 patients and 11 cadaveric controls , we show that the mineral and organic chemical composition of trabecular bone in ON is not modified apart from age - related differences . - pubmed
RESULTS : Two patients ( 1.4 % ) developed postoperative complications requiring redo surgery . - pubmed
CONCLUSION : The ELAR technique with mesh augmentation is an innovative , minimally invasive surgical procedure for treatment of patients with a complex abdominal wall hernia comprising symptomatic umbilical , trocar , and/or epigastric hernias with concomitant rectus abdominis diastasis . - pubmed
Brucellosis is regarded as one of the most common diseases among humans and livestock . - pubmed
The present case - study was carried out on 40 patients with brucellosis ( case ) and 20 healthy people ( control ) . - pubmed
Moreover , the present study indicated that brucellosis produces oxidative stress in patients . - pubmed
Subsequent maternal separation exacerbates neurobehavioral abnormalities in rats neonatally exposed to sevoflurane anesthesia . - pubmed
Several recent studies suggest that in the human population , a routine , short anesthetic in otherwise healthy infants is void of neurodevelopmental insult . - pubmed
On the other hand , many human retrospective epidemiological studies report evidence of cognitive abnormalities in children after testing those who had different anesthesia - requiring procedures in early childhood . - pubmed
Despite posing a challenge for the unsuspecting physician , an early diagnosis of granulomatous mastitis improves patient outcomes . - pubmed
Potential Impact of Metabolic and Gut Microbial Response to Pregnancy and Lactation in Lean and Diet - Induced Obese Rats on Offspring Obesity Risk . - pubmed
METHODS AND RESULTS : 1 H NMR serum metabolomics analysis was performed on samples collected pre - pregnancy and in pregnant and lactating lean and high fat / sucrose ( HFS ) diet - induced obese Sprague - Dawley rats to identify maternal metabolic pathways associated with developmental programming of offspring obesity . - pubmed
A case of empyema and septic arthritis due to Nocardia farcinica . - pubmed
There is paucity of information on how glaucoma affects the quality of life of patients in low and middle - income countries where resources for both diagnosis and treatment of such conditions are limited . - pubmed
In this study we investigate the impact of glaucoma on quality of life in Ethiopian patients . - pubmed
METHODS : The quality of life of 307 glaucoma patients and 76 normal controls that were frequency matched to the age and sex profiles of the cases was assessed using Amharic version of Glaucoma Quality of Life -15 questionnaire . - pubmed
PATIENT CONCERNS : This is the case of a 73 - year - old man who reported to the Clinic of Cranio - Maxillofacial and Oral Surgery and Implantology , Medical University of Warsaw , owing to a skin tumor in the right parotideomasseteric region , initially diagnosed as discoid lupus erythematosus . - pubmed
INTERVENTIONS : The patient was transferred to the Lymphoid Tumours Clinic of the Maria Sklodowska Curie Memorial Cancer Centre and Institute of Oncology in Warsaw , where chemotherapy was initiated . - pubmed
Misdiagnosis can lead to inappropriate therapy and result in disease progression or unnecessary harm to the patient . - pubmed
This study investigated whether early signs of attention deficit hyperactivity disorder ( ADHD ) in toddlers aged 2 - 3 years are associated with disturbed sleep and activity levels . - pubmed
Comparison of conservative exercise therapy with and without Maitland Thoracic Manipulative therapy in patients with subacromial pain : Clinical trial . - pubmed
OBJECTIVE : To determine the effect of conservative exercise therapy with and without Maitland thoracic manipulation in patients with subacromial pain . - pubmed
METHODS : The randomised controlled trial study was conducted at the Mayo Hospital , Lahore , Pakistan , from June 2015 to February 2016 , and comprised patients with subacromial pain ( group 1 ) and controls ( group 2).Pre - assessment was done by using numeric pain rating scale and shoulder pain and disability index as subjective measurements , while range of motion was taken as objective measurement . - pubmed
Moreover , heart / body weight ratio and ventricular interstitial fibrosis were increased in TAC - operated WT mice compared with that of sham - operated WT mice . - pubmed
However , there are still relatively few studies about circadian rhythms in neuromyelitis optica spectrum disorders ( NMOSD ) and 2D2 transgenic mice . - pubmed
2D2 mice might be a suitable model for studying circadian disruption in NMOSD . - pubmed
Here , we describe the synthesis of ( E )- 2 - isopropyl-5 - methyl-4 -(( 2 -( pyridin-4 - yl ) hydrazono ) methyl ) phenol ( 18 ) , which binds ferriprotoporphyrin - IX ( FeIII - PPIX ) ( Kd = 33 nM ) and offers antimalarial activity against chloroquine - resistant and sensitive strains of Plasmodium falciparum in vitro . - pubmed
berghei ANKA ( causing cerebral malaria ) in mice with negligible toxicity . - pubmed
Human dermal fibroblast is essential in wound healing of the skin through the synthesis of extracellular matrix proteins . - pubmed
Remifentanil treatment increased the proliferation of human dermal fibroblast and decreased apoptotic cell death , enhancing autophagic activity under oxidative stress . - pubmed
This study demonstrates that remifentanil activated autophagy and decreased apoptotic death of human dermal fibroblasts under oxidative stress . - pubmed
PARTICIPANTS : Thirty - one individuals ( 21 men and 10 women ; mean age , 60 years ) , who had poststroke hemiparesis . - pubmed
BACKGROUND : Although accumulated evidence provides a strong scientific premise for using immune profiles to predict survival in patients with cancer , a universal immune profile across tumor types is still lacking , and how to achieve a survival - associated immune profile remains to be evaluated . - pubmed
Intriguingly , this immune profile transformation led to inhibition of metastasis and to prolonged survival in both mouse and patient - derived xenograft malignant models . - pubmed
Impacts of Escherichia coli infection in young breeder chicks on the behavior and cerebral activity of purinergic and cholinergic enzymes involved in the regulation of molecules with neurotransmitter and neuromodulator function . - pubmed
Macroscopically , pericarditis and hepatic congestion were observed in the birds , but without histopathological lesions in the encephalon although the bacterium was present in the cerebral cortex of all animals in the infected group ( i.e. - pubmed
Gluten , a group of proteins found in wheat , barley , and rye , is the trigger of celiac disease , an immune disorder that affects about 1 % of people worldwide . - pubmed
TNBC patient prognosis , survival and response to current therapies are poor and for this reason it is crucial to search new therapeutic targets in TNBC to develop new therapeutic strategies . - pubmed
METHODS : In a cross - sectional study , 18 PD patients ( 13 M/5F , 64 + - 7 years , range 46 - 74 years , disease duration 2.9 + - 2.6 years ; UPDRS motor 21.9 + - 5.2 ) and 20 age- and gender - matched healthy control ( HC ) subjects ( 15 M/5F , 61 + - 7 years , range 50 - 72 years ) were included . - pubmed
In a subsequent longitudinal phase , ten of the PD patients ( 7 M/3F , UPDRS motor 20.6 + - 6.9 ) underwent a second PET measurement after 18 - 24 months . - pubmed
RESULTS : The univariate region - based analysis showed no differences in SERT levels when the PD patients were compared with the HC neither at baseline or after 2 years of follow - up . - pubmed
CONCLUSION : We conclude that the serotoninergic system in PD patients seems to become involved with a network dysregulation as the disease progresses , suggesting a disturbed serotonergic signaling from raphe nuclei to target subcortical and cortical regions . - pubmed
Patients with prolactinoma , corticotroph adenoma , and Rathke ' s cleft cyst had small sellar masses ( < 1 centimeter ) while the majority of patients with other SMs had macroadenomas . - pubmed
Hypogonadism and growth hormone deficiency was present in 41.8 % and 20.5 % of the patients , respectively . - pubmed
BACKGROUND : Patients with focal segmental glomerulosclerosis ( FSGS ) characterized by steroid - resistant nephrotic syndrome ( SRNS ) are prone to progress to ESRD . - pubmed
Mechanism for the FSGS patients ' response to steroid treatment is still unknown and currently , it is impossible to predict the steroid resistance before treatment of patients with FSGS . - pubmed
METHODS : To identify biomarkers and potential therapeutic targets of FSGS patients with SRNS , patients diagnosed as kidney biopsy - proven FSGS and nephrotic syndrome ( NS ) were prospectively enrolled . - pubmed
Additionally , the system was capable of penetrating human skin beyond the stratum corneum , which enhances the potential of these nanoclusters as bifunctional photodynamic therapy effectors and biomarkers with application in a diversity of skin diseases . - pubmed
Three species accounted for around 60 % of the strains : F. - pubmed
OBJECTIVE : Patients with unilateral deafness and residual hearing on the contralateral ear can benefit from a cochlear implant ( CI ) on one side and a hearing aid ( HA ) on the other . - pubmed
In this focused and histology - guided study , tissue from a patient diagnosed with aggressive BCC was analyzed by imaging mass spectrometry in order to probe the chemistry of the complex tumor environment . - pubmed
Comparison of the long - term efficacy between tenofovir and entecavir in chronic hepatitis B patients . - pubmed
Oropharyngeal cancer is a subtype of head and neck squamous cell carcinoma that is associated with unique risk exposures like consumption of smokeless tobacco and areca nut and is highly prevalent in the northeastern region of India , especially Meghalaya . - pubmed
HPV DNA sequences were not detected in any of the tumor samples in RNA - Seq data . - pubmed
Introduction : Various studies are being conducted because of the value of finding an appropriate medication to control bleeding in patients with epistaxis faster and more conveniently . - pubmed
Methods : This randomized clinical trial enrolled patients with epistaxis presenting to the emergency departments of two hospitals affiliated to Tabriz University of Medical sciences . - pubmed
Primary outcome variables included bleeding control time and patient satisfaction . - pubmed
Results : Epistaxis was controlled in less than 5 minutes in 85 ( 79.4 % ) patients in the intervention group and 85 ( 88.5 % ) patients in the control group ( P=0.058 ) . - pubmed
In the intervention group , 10 patients experienced recurrence of epistaxis within 24 hours of treatment , while 9 patients in the control group experienced recurrence ( P= 0.591 ) . - pubmed
Conclusion : Based on the findings , bleeding control time was similar in the two groups , but patient satisfaction was higher in Traumastem group . - pubmed
The clinical utility of computed tomographic scanning and neurologic examination in the management of patients with minor head injuries . - pubmed
To validate this hypothesis we studied 2766 patients with an isolated MHI admitted to seven trauma centers between January 1 , 1988 , and December 31 , 1991 . - pubmed
There were 1898 male patients and 868 female patients ; injury was blunt in 99 % . - pubmed
Occurrence of cataracts in triploid Atlantic salmon ( Salmo salar ) on four farms in Scotland . - pubmed
In September 1991 cataracts occurred in two year - classes of triploid Atlantic salmon . - pubmed
During the period mentioned above there ware hospitalized 54 patients having epibulbar tumours . - pubmed
The anatomopathological exam which was effectuated for 33 patients he s shown Bowen 's disease for 14 cases , spinocellular carcinoma for 15 patients and basocellular for 3 patients . - pubmed
There was retinoblastoma for 19 cases ; it had been practiced the enucleation of ocular globe for 17 patients and for two cases it had been practiced the exenteration of the eye socket . - pubmed
The hepatic scintigraphy was practiced for 56 patients and had shown for 8 cases hepatic metastasis . - pubmed
We have attempted to define the synergistic interaction between immuno- and chemotherapy further , using the murine irradiated vaccine model of schistosomiasis mansoni . - pubmed
[ Eosinophilia and giardia lamblia intestinal parasitism ] . - pubmed
[ Binding of ( 3)-imipramine by platelets from spontaneously hypertensive , normotensive , and Wistar rats and their behavior in stressful situations ] . - pubmed
Spontaneously hypertensive rats ( SHR ) , when submitted to stress remained active during both avoidance ( water escape task test ) and nonavoidance ( forced swimming test ) stress - situations . - pubmed
Wistar rats responded to a depression of active behaviour in forced swimming test and difficulty at resolving of complicated problem in water escape task test . - pubmed
Effect of intrinsic sympathomimetic activity on the ability of hypertensive patients to derive a cardiorespiratory training effect during chronic beta - blockade . - pubmed
The effect of intrinsic sympathomimetic activity ( ISA ) on the ability of patients with high blood pressure ( BP ) to derive a cardiorespiratory training effect during long - term beta - blocker therapy was studied . - pubmed
Fifty sedentary hypertensive subjects were randomly assigned to propranolol ( n = 23 ) or pindolol ( n = 27 ) therapy for a 22 week double - blind parallel study . - pubmed
Five normal subjects and 10 patients , of whom 5 presented esophageal achalasia and 5 gastroesophageal reflux disease , underwent computerized esophageal manometry and were evaluated on the basis of both traditional and innovative parameters , of our own inception . - pubmed
In both adults and children , postassault infections with viral agents of STDs , including herpes simplex viruses , hepatitis B virus , and human immunodeficiency virus , have been described . - pubmed
To test the effects of chronic hypoxia without an antecedent hyperoxic injury in the kitten , the animals were raised in 13 % or 21 % ( room air ) oxygen and their retinas examined at 3 , 7 , 14 , or 21 days . - pubmed
Effect of DMBA on oral cancer development in hamsters with latent HSV-1 infections in trigeminal ganglia . - pubmed
This study examined the effect of 7 , 12 - dimethyl - benz ( a ) anthracene ( DMBA ) , polycyclic aromatic hydrocarbon carcinogen , on pathologic changes in buccal pouch mucosa of hamsters with latent herpes simplex virus type 1 ( HSV-1 ) infections in their trigeminal ganglia . - pubmed
Of the pouches receiving DMBA , the average cumulative tumor diameter ( the sum of the tumor diameters in each group divided by the number of pouches in that group ) was notably greater in animals with latent HSV-1 than in animals that had not been infected ; however , this difference was not significant . - pubmed
The DMBA - treated hamsters that had latent infections also displayed a higher severity and prevalence of histopathologic changes in their pouch mucosa . - pubmed
This study indicates that latent HSV-1 and DMBA show synergism in the development of tumors and precancerous histopathologic changes in hamster buccal pouch mucosa . - pubmed
Of the 35 subjects with DS , 16 had values of 60 - 84 micrograms / dl ( mean 74.25 + /- 8.29 micrograms / dl ) ( table I ) , which are well below normal . - pubmed
Out of 16 patients with low zinc values 10 ( 68.5 % ) were particularly susceptible to infections . - pubmed
In hypothyroid rats , endotoxin administration increased the rates of glycolysis in muscle in vitro . - pubmed
Ventricular dysfunction induced by dipyridamole would be evidence of myocardial ischemia in patients with limited ability to undergo standard exercise testing . - pubmed
Among these patients , 21 ( 68 % ) had significant coronary artery disease ( greater than or equal to 50 % stenosis ) , 19 ( 61 % ) had severe coronary disease ( greater than or equal to 70 % stenosis ) and 10 ( 32 % ) were " normal " ( less than 50 % stenosis ) . - pubmed
However , in patients with coronary artery disease , the ejection fraction failed to increase during exercise or after dipyridamole . - pubmed
In the patients with coronary artery disease , regional wall motion decreased by 4.1 + /- 0.5 units during exercise ( p less than 0.003 ) and by 1.8 units after dipyridamole ( p less than 0.02 ) . - pubmed
Specific subsets of patients with severe coronary atherosclerosis were analyzed with use of these criteria . - pubmed
In patients with severe stenosis ( greater than or equal to 70 % ) , the sensitivity of dipyridamole ventriculography was 67 % compared with 89 % for exercise ventriculography . - pubmed
This technique provides a widely applicable , useful alternative to exercise ventriculography in the diagnosis of coronary atherosclerosis in patients who have limited exercise tolerance . - pubmed
The use of this technique is demonstrated for the cloning of a sequence from within the human alpha - globin complex that was previously shown to be " unclonable " in bacteriophage and cosmid vectors and which is a multiallelic general genetic marker , as well as both beta - globin alleles from an individual with beta - thalassaemia . - pubmed
Haldane himself rejected the simple explanation that males are innately more sensitive than females to the effects of hybridization because groups with heterogametic females ( such as birds and butterflies ) usually show female sterility in hybrids , so that heterogamety itself is the critical feature . - pubmed
Light sensitivity of the central and peripheral parts of the human retina has been studied in an hour exposure to broadband noise of 95 dBA intensity and in an after - effect period . - pubmed
[ Refractive errors among children . - pubmed
Emergency management of unexpected defects of hemostatic function in surgical patients . - pubmed
Nondialysable sugar - peptide fraction in the plasma of diabetic patients . - pubmed
Vomiting and wasting disease in piglets . - pubmed
[ Action of reserpine and of one of its derivatives on compensatory ovarian hypertrophy in the female rat ] . - pubmed
Nature of immunity to Newcastle disease in vaccinated chickens . - pubmed
[ Experience in saving 8 patients with ventricular tachycardia ] . - pubmed
An experimental model in rats was developed to define the nature of humoral and cellular factors that contribute to impaired immune responsiveness in chronic renal failure . - pubmed
Addition of uremic rat serum to both normal and uremic lymphocytes significantly suppressed cellular responses , the suppression being more pronounced with uremic lymphocytes . - pubmed
Thus the effect on antibody response in uremic animals is dependent upon the antigen tested . - pubmed
[ Atrial septal defect in 3 patients over 70 years of age ] . - pubmed
From March 1971 to September 1973 , 200 patients with primary bronchogenic carcinoma received 4,000 rad ( 40 Gy ) by means of split - course accelerated fractionation . - pubmed
Forty - five patients ( 22.5 % ) survived more than 11 months ; and of these , 6 ( 13.3 % ) were found to have progressive myelitis . - pubmed
Zinc and copper levels in plasma , erythrocytes , and whole blood in cancer patients . - pubmed
Zinc and copper levels in erythrocytes , plasma , and whole blood were determined in 35 cancer patients and compared with 24 normal individuals . - pubmed
A decrease in zinc was found in all three blood constituents of the cancer patients . - pubmed
Further investigations are indicated to determine whether these two elements could serve as indicators for diagnosis or prognosis in cancer patients . - pubmed
The first patient had no antecedent ear disease and developed a large Bezold abscess caused by Fusobacterium varium . - pubmed
This patient developed labyrinthitis and meningitis due to B. - pubmed
Thirty - two young athletes ( ages ranging from 17 to 30 years ) with a clinical diagnosis of a symptomatic lumbar disc and sciatica were treated with lumbar epidural cortisone injections . - pubmed
The serum levels and urinary excretion of magnesium and copper were studied in 66 patients with either acute myocardial ischemia or myocardial infarction . - pubmed
The initial serum magnesium levels were normal in patients with ischemia but were low in some patients with myocardial infarction . - pubmed
Patients developing ventricular arrhythmias with myocardial infarction showed the lowest levels of serum magnesium . - pubmed
Copper in the serum appeared elevated in patients developing acute congestive heart failure but the elevation was not statistically significant . - pubmed
These data indicate that a decrease in serum magnesium as evaluated may be associated with ventricular arrhythmias in patients with myocardial infarction ; thus continued observations of magnesium levels in the myocardial infarction patient is warranted . - pubmed
MATERIALS AND METHODS : A review of all arthroscopic reports from two institutions during the periods 1990 - 1992 and 1992 - 1993 , respectively , revealed 13 patients with partial tears of the ACL . - pubmed
BACKGROUND : Renal cell carcinoma is a frequent cause of morbidity and mortality in patients with von Hippel - Lindau disease . - pubmed
METHODS : A review was conducted of 10 patients with von Hippel - Lindau disease and localized renal tumors , who underwent renal parenchyma - sparing surgery . - pubmed
Four patients had recurrences , requiring a total of 16 operations . - pubmed
Patients were followed for recurrence by computed tomography . - pubmed
Of the 10 patients , 2 died , one of primary lung cancer with recurrent renal cell carcinoma found at autopsy , and one of metastatic renal cell carcinoma . - pubmed
The other seven patients were alive and without evidence of renal cancer . - pubmed
CONCLUSION : Although the risk of recurrence is high , these patients may be treated with parenchyma - sparing renal surgery and enjoy a prolonged survival , and avoid the complications of dialysis or transplantation . - pubmed
A 26 - year - old woman with mononeuropathy multiplex complained of severe pain of right foot and ipsilateral steppage gait . - pubmed
This is the first report of a patient with NSN showing positive ANCA . - pubmed
Histopathology of the small intestinal mucosa in Nematodirus spathiger infection in rabbits . - pubmed
These distal variations were similar to those previously described in experimental Trichostrongylus colubriformis infections of rabbits . - pubmed
These results tend to confirm the use of the rabbit as an experimental model to study Nematodirus infection . - pubmed
The objective of this article is ( 1 ) to review the range of anterior segment ocular disease caused by varicella - zoster virus ( VZV ) , ( 2 ) to discuss the pathophysiology of the mechanisms involved in the ensuing tissue damage , and ( 3 ) to bring the reader up to date on the current management and therapy of herpes zoster ophthalmicus ( HZO ) . - pubmed
Diagnostic testing for dementia in patients with Parkinson ' s disease . - pubmed
We describe the case of a patient who presented with recurrent acute hemarthrosis after anterior cruciate ligament reconstruction without additional trauma and without instability . - pubmed
White matter MR hyperintensities in adult patients with congenital rubella . - pubmed
PURPOSE : To observe and quantify white matter hyperintensities on MR images in adults with schizophrenialike symptoms who had had congenital rubella , in order to elucidate the neuropathologic sequelae of this perinatal viral infection and to explore the potential relationship of these lesions to schizophrenia . - pubmed
METHODS : Eleven deaf adult patients with documented prenatal rubella virus infection and schizophrenialike symptoms were compared with 19 age - matched patients with early - onset schizophrenia who did not have congenital rubella and with 18 age - matched control subjects . - pubmed
RESULTS : Ratings of white matter lesions were significantly higher in the rubella patients than in the control subjects : 6 of the 11 patients had ratings greater than 1 compared with 1 of the 18 control subjects and none of the 19 schizophrenic patients . - pubmed
Also , MR images in five rubella patients received ratings at the highest end of the scale of abnormality ( 3 or 4 ) . - pubmed
Effect of combination therapy with lipid - reducing drugs in patients with coronary heart disease and " normal " cholesterol levels . - pubmed
BACKGROUND : Combination drug therapy has been shown to decrease cholesterol levels in hyperlipidemic patients . - pubmed
Social phobia in disabled workers with chronic musculoskeletal pain . - pubmed
Most patients were had been taking benzodiazepines because of panic disorder or neurosis . - pubmed
During the withdrawal the patients were rated daily for anxiety , mood alterations , perception disturbances , neurological symptoms , and vegetative signs . - pubmed
Most patients showed sleep disturbances , mood alterations or anxiety . - pubmed
Because anxiety , the reason for the benzodiazepine treatment in many cases , often recurs , the patients must be offered continuous after - care to prevent a new dependence . - pubmed
Some of the new insights on the origins of radiation induced chromosome aberrations in human , mouse and Chinese hamster , using FISH are reviewed in this paper . - pubmed
The development of gynecomastia in male patients treated with ketoconazole has led to investigation of its potent inhibitory effect on adrenal steroidogenesis . - pubmed
In this study , we present our preliminary experience using high dose ketoconazole , which was used safely as a palliative treatment in 3 patients with Cushing ' s syndrome prior to surgery . - pubmed
The most significant improvement of clinical symptoms was that the patients could sleep much more comfortably at night following the suppression of hypercortisolism by ketoconazole . - pubmed
In this study , the ictal phenomena of dystonic limb posturing , tonic limb posturing , unilateral immobile limb , and version were distinguished and examined in patients with temporal and extratemporal seizures . - pubmed
METHODS : Partial seizures in 54 patients , successfully treated by surgery ( 34 temporal , 20 extratemporal ; 14 frontal , 3 parietal , and 3 occipital ) , were analyzed blindly by 3 reviewers . - pubmed
RESULTS : In patients with temporal lobe epilepsy ( TLE ) , dystonic posturing occurred in 35.3 % ( kappa 0.78 , positive predictive value ( PPV ) for the sign being contralateral to seizure onset 92 % ) ; tonic limb posturing occurred in 17.7 % ( kappa 0.36 , PPV 40 % ) ; unilateral immobile limb occurred in 11.8 % ( kappa 0.23 , PPV 100 % ) ; and version occurred in 35.3 % ( kappa 0.77 , PPV 100 % ) . - pubmed
In patients with extratemporal epilepsy , dystonic posturing occurred in 20.0 % ( kappa 0.31 , PPV 100 % ) ; tonic limb posturing occurred in 15.0 % ( kappa 0.08 , PPV 67 % ) ; and version occurred in 40.0 % ( kappa 0.54 , PPV 100 % ) . - pubmed
Reduced responsiveness of rat mesenteric resistance artery smooth muscle to phenylephrine and calcium following myocardial infarction . - pubmed
The diagnosis in each case was very difficult , being mistaken with tuberculosis in two of the patients and with paraneoplasic myelopathy in the other one . - pubmed
A group of 87 patients suffering from unilateral sudden hearing loss were investigated . - pubmed
Twenty - five percent of the patients had accompanying vertigo . - pubmed
Vertigo occurred more often in patients with severe hearing loss in high tone frequencies . - pubmed
Hearing recovery of high tone frequencies was poorer in the patients with vertigo than in those without it , although the initial hearing loss was the same . - pubmed
The chromosome aberration test using cultured mammalian cells is one of the sensitive methods to predict environmental mutagens and/or carcinogens , and is a complementary test to the Salmonella / microsome assay ( Ames test ) . - pubmed
The selected viruses grew well on Vero cells , but both mutants exhibited a growth defect on swine macrophages at low multiplicities of infection ( MOI ) , yielding 0.1 to 1.0 % of wild - type levels . - pubmed
The Malawi TK deletion mutant showed reduced virulence for swine , producing transient fevers , lower viremia titers , and reduced mortality . - pubmed
Swine surviving TK- ASFV infection remained free of clinical signs of African swine fever following subsequent challenge with the parental pathogenic ASFV . - pubmed
Detection of HPV-16 genome in human oral cancers and potentially malignant lesions from India . - pubmed
The presence of high risk human papilloma virus ( HPV ) 16 and 18 was examined in 100 oral cancer patients of Indian descent , 80 patients with potentially malignant oral lesions and corresponding clinically normal mucosa from 48 of these patients . - pubmed
Additionally , presence of HPV-33 , -6 and -11 was also studied in 86 oral cancers , 50 potentially malignant oral lesions and 30 corresponding normal oral mucosa . - pubmed
HPV-16 was detected in 15 out of 100 ( 15 % ) oral tumours , 27 out of 80 ( 34 % ) potentially malignant lesions and 15 out of 48 ( 31 % ) of the corresponding normal mucosa in the patients with oral lesions . - pubmed
HPV-18 was not detected in any of the oral cancers , oral lesions and normal mucosa . - pubmed
HPV-33 and the low - risk HPV-6 and -11 were also not detected in the oral cancers , oral lesions and corresponding normal mucosa . - pubmed
A significantly higher prevalence of HPV-16 was observed in oral lesions ( 27 out of 80 , 34 % ) as compared to oral cancers ( 15 out of 100 , 15 % ) . - pubmed
Our data indicates that HPV-16 may play a direct role in a certain proportion of oral cancers ; whereas in a subpopulation of oral cancers HPV-16 infection may be vital in the early events associated with development of potentially malignant oral lesions , and the presence of the virus not essential in the progression of the oral lesion to frank malignancy . - pubmed
In rats , the length of lactational anovulation is prolonged when litter size is increased or when the dam is food restricted . - pubmed
In patients with sufficient bone height but insufficient bone width as a result of tooth loss , a jaw enlargement technique with osteotomes combined with soft tissue manipulation may be utilized to facilitate proper implant placement while concomitantly optimizing the aesthetics of the final implant prosthesis . - pubmed
Re : orthotopic urinary diversion with preservation of erectile and ejaculatory function in men requiring radical cystectomy for nonurothelial malignancy : a new technique . - pubmed
We compared early and late outcome of patients with complex coronary lesions in small vessel treated with traditional coronary angioplasty ( angioplasty group ) and with elective stent implantation ( stent group ) . - pubmed
No patients in the two groups experienced in - hospital death or bypass surgery . - pubmed
Myocardial infarction occurred in four patients in the angioplasty group and in seven patients in the stent group ( P = 0.36 ) . - pubmed
No patients in either the angioplasty or the stent group had acute stent thrombosis , whereas subacute stent thrombosis occurred in only one patients of the stent group ( 0.9 % ) . - pubmed
Lung transplantation has become a valid therapeutic option for cystic fibrosis patients with end - stage lung disease . - pubmed
BACKGROUND : Panic attacks can be induced in persons with panic disorder by inhalation of carbon dioxide . - pubmed
METHODS : Twelve patients with PD received biperiden hydrochloride ( a muscarinic antagonist that crosses the blood - brain barrier ) , pirenzepine hydrochloride ( a muscarinic antagonist that does not cross the blood - brain barrier ) , or placebo 2 hours before a 35 % carbon dioxide-65 % oxygen respiratory challenge ( vs air as a placebo ) on 3 separate days , in a double - blind , random crossover design . - pubmed
RESULTS : According to patients ' self - ratings of subjective anxiety , inhalation of the carbon dioxide / oxygen mixture provoked a significant and intense response after treatment with pirenzepine and placebo . - pubmed
We found that infection by cytomegalovirus ( CMV ) resulted in substantial increases in MIC on cultured fibroblast and endothelial cells and was associated with induced MIC expression in interstitial pneumonia . - pubmed
High - volume haemofiltration in human septic shock . - pubmed
PATIENTS : Eleven patients with septic shock and multi - organ failure . - pubmed
An apparent hypersensitivity reaction ( bronchospasm and decrease in blood pressure ) had occurred during heart transplantation in a 59 - year - old woman after intravenous infusion of cyclosporine . - pubmed
In previous studies , we synthesized two classes of electrophilic tocopheryl quinones ( TQ ) , nonarylating alpha - TQ and arylating gamma- and delta - TQ , and found that gamma- and delta - TQ , but not alpha - TQ , were highly cytotoxic in human acute lymphoblastic leukemia cells ( CEM ) and multidrug - resistant ( MDR ) CEM / VLB100 . - pubmed
We have now extended these studies on tumor biology with CEM , HL60 and MDR HL60 / MX2 human promyelocytic leukemia , U937 human monocytic leukemia , and ZR-75 - 1 breast adenocarcinoma cells . - pubmed
Serial dexamethasone suppression tests ( DST ) , obtained during a course of electroconvulsive therapy in 43 severely depressed patients , did not exhibit relationships between the initial DST , final DST , or the change in DST with clinical outcome measures at the time of discharge . - pubmed
We are unable to confirm a clinical application for the DST in the management of patients during a course of convulsive therapy . - pubmed
PARTICIPANTS : Patients were 51 neurologic intensive care patients with an intracranial disease requiring a central venous catheter due to the primary ( intracranial ) disease . - pubmed
We excluded patients under the age of 19 yrs and those with active cardiac arrhythmia , full sepsis syndrome , bleeding diathesis and infection , or bleeding at the site of the intended catheter insertion . - pubmed
was comparable to the rate usually observed in our neurologic intensive care patients with such severe intracranial diseases . - pubmed
One awake patient ( subarachnoid hemorrhage , Glasgow Coma Scale score 15 ) experienced mild to moderate shivering throughout the entire period of 7 days . - pubmed
CONCLUSION : This novel intravascular cooling device ( Cool Line catheter and Cool Gard cooling device ) was highly efficacious in prophylactically controlling the body temperature of neurologic intensive care patients with very severe intracranial disease ( median Glasgow Coma Scale score , 3 - 15 ) . - pubmed
Adrenal suppression in asthmatic children receiving low - dose inhaled budesonide : comparison between dry powder inhaler and pressurized metered - dose inhaler attached to a spacer . - pubmed
OBJECTIVE : The purpose of this study was to evaluate the prevalence of adrenal suppression in children using low - dose budesonide given by DPI , as compared with pMDI attached to a large - volume spacer device ( pMDI + spacer ) . - pubmed
METHODS : In an open - labeled crossover study , 15 asthmatic children aged 5 to 15 years received 200 microg of inhaled budesonide twice daily by DPI ( Turbuhaler , Astra , Draco AB , Lund , Sweden ) and by pMDI + spacer , 1 month each , in a randomized order . - pubmed
CONCLUSIONS : Treatment of asthmatic children with budesonide 400 microg daily given via a DPI for 1 month was associated with hypothalamic - pituitary - adrenal axis suppression . - pubmed
Three patients with carotid artery ( CA ) pseudoaneurysms were treated using four polyethylene terephthalate endografts ( Wallgraft endoprostheses ) . - pubmed
Two patients received a single graft and one patient with bilateral pseudoaneurysms received two grafts . - pubmed
Complete occlusion of the pseudoaneurysm with patency of the arterial lumen was achieved following endograft placement in all patients . - pubmed
One patient experienced neurological symptoms , and in - graft stenosis ranging from 50 to 100 % occurred in three of the four grafts . - pubmed
Although the Wallgraft endoprosthesis produced good initial results for the treatment of cervical CA pseudoaneurysms , as demonstrated on radiography , it was associated with a high rate of stenosis or occlusion in all three patients . - pubmed
OBJECTIVES : Despite clinical use , the radiosensitizing effect of gemcitabine ( 2'2 '- difluorodeoxycytidine ) in human transitional cell carcinoma ( TCC ) has not been shown to date . - pubmed
Examining responses of the local immune system of the brain in neurocancer patients suggests that the immune system is involved in the neuroimmune interaction of both physiological and pathological conditions in the central nervous system ( CNS ) . - pubmed
The vertical distribution of Simulium damnosum bites on the human body . - pubmed
Liver transplantation in patients with intrahepatic stones : report of two cases . - pubmed
METHODS : Liver transplantation was successfully performed for a 28 - year - old man and a 42 - year - old woman , both with intrahepatic stones . - pubmed
RESULTS : Patient 1 had digestive tract bleeding on the postoperative day 6 and he was discharged from the hospital on the postoperative day 25 . - pubmed
Patient 2 also had hemorrhage from the digestive tract on the postoperative day 44 and a leakage of end - to - side intestinal anastomosis on the postoperative day 47 . - pubmed
CONCLUSION : Liver transplantation is safe and effective for patients with intrahepatic stones . - pubmed
We previously reported that heteroplasmic point substitutions in the mitochondrial DNA D - loop were found in 15 of 75 children at risk for mitochondrial disease ( vs 0/95 controls ) . - pubmed
Gemcitabine and low dose carboplatin in the treatment of elderly patients with advanced non - small cell lung cancer . - pubmed
BACKGROUND : Fifty percent of lung cancers arise in patients over 65 years old and 30 % in those over 70 . - pubmed
The aim of this study was to evaluate response , survival and tolerability of the combination carboplatin - gemcitabine in elderly patients with advanced non - small cell lung cancer ( NSCLC ) . - pubmed
WHO grades 3 - 4 toxicities were : neutropenia in 13 % of the cycles , thrombocytopenia and anaemia in 4.5 and 14.7 % of patients in any cycle . - pubmed
CONCLUSIONS : The combination carboplatin - gemcitabine at these doses is feasible in elderly patients with advanced non - small cell lung cancer . - pubmed
The women in dysfunctional labor had higher capillary lactate and lower capillary O ( 2 ) saturation . - pubmed
OBJECTIVE : This study reviewed patients with unilateral facial paralysis and normal clinical and imaging findings who underwent diagnostic facial nerve exploration . - pubmed
Study design and setting Fifteen patients with facial paralysis and normal findings were seen in the Mayo Clinic Department of Otorhinolaryngology . - pubmed
RESULTS : Eleven patients were misdiagnosed as having Bell palsy or idiopathic paralysis . - pubmed
Progressive facial paralysis with sequential involvement of adjacent facial nerve branches occurred in all 15 patients . - pubmed
Seven patients had a history of regional skin squamous cell carcinoma , 13 patients had surgical exploration to rule out a neoplastic process , and 2 patients had negative exploration . - pubmed
CONCLUSIONS : Patients with facial paralysis and normal clinical and imaging findings should be considered for facial nerve exploration when the patient has a history of pain or regional skin cancer , involvement of other cranial nerves , and prolonged facial paralysis . - pubmed
SIGNIFICANCE : Occult malignancy of the facial nerve may cause unilateral facial paralysis in patients with normal clinical and imaging findings . - pubmed
Topiramate is a novel anticonvulsant that may induce weight loss in some patients . - pubmed
This is the first study to address the long - term efficacy and impact on weight of the combination of olanzapine and topiramate in bipolar patients . - pubmed
Twenty - six Diagnostic and Statistical Manual of Mental Disorders , Fourth Edition bipolar spectrum patients received olanzapine plus topiramate cotherapy for treatment of their manic ( n = 14 ) , hypomanic ( n = 6 ) , depressive ( n = 2 ) , and mixed ( n = 1 ) symptoms for 1 year . - pubmed
RESULTS : The most constant responses in adrenal incidentalomas were observed after stimulation by terlipressin ( 18/20 patients , 28 - 415 % cortisol increase ) and cisapride ( 17/21 patients , 25 - 364 % cortisol increase ) . - pubmed
Chronic oral toxicity of a high gel point methylcellulose ( methocel HG ) in rats and dogs . - pubmed
Verbal perseveration in individuals with Alzheimer ' s disease . - pubmed
The study investigated the frequency of verbal perseveration in individuals with AD in relation to task type , mental status , and performance on attention and memory tests . - pubmed
Early invasive strategy in elderly patients with non - ST elevation acute coronary syndrome : comparison with younger patients regarding 30 day and long term outcome . - pubmed
METHODS : All consecutive patients admitted with a diagnosis of non - ST elevation ACS from June 2002 to February 2004 were enrolled in this registry . - pubmed
RESULTS : An early invasive strategy was followed for 439 patients , of whom 159 ( 36 % ) were elderly and had a higher clinical risk profile and greater extent of coronary artery disease ( CAD ) than the younger patients . - pubmed
At a mean ( SD ) follow up time of 10.7 ( 5.2 ) months overall mortality , cardiac death , and death plus myocardial infarction were significantly higher among elderly patients than among younger patients ( 9.4 % v 2.1 % , p & lt ; 0.001 ; 6.8 % v 1.8 % , p & lt ; 0.01 ; 11.3 % v 5 % , p = 0.02 , respectively ) . - pubmed
The significant difference in cardiac death between the two groups was related more to elderly patients being treated by coronary artery bypass grafting ( 19.3 % v 4.9 % , p = 0.05 ) than by percutaneous coronary intervention ( PCI ) ( 2.9 % v 1.1 % , p = 0.3 ) . - pubmed
Kaplan - Meier analysis showed that patients with low beta - catenin expressing tumors trended toward worse 5 - year disease - free survival ( P = 0.06 ) . - pubmed
Of the 57 patients , 14 ( 24.6 % ) ( mean age , 70+/-4.6 years ) were diagnosed as having gastroesophageal reflux disease with the use of conventional method . - pubmed
After correction , gastroesophageal reflux disease diagnosis was made in 6 additional patients ( mean age , 2.4+/-2.4 years ) and total number of patients with reflux increased to 20 ( 35.1 % ) ( p=0.031 ) . - pubmed
Natural transmission of Johne ' s disease to feral goats . - pubmed
Behavioural studies on the potential for direct transmission of tuberculosis from feral ferrets ( Mustela furo ) and possums ( Trichosurus vulpecula ) to farmed livestock . - pubmed
Tuberculous possums commonly and tuberculous ferrets less commonly have lung lesions and/or discharging sinuses , and may excrete Mycobacterium bovis intermittently or continuously in aerosols or discharges . - pubmed
Patients with an index of 30 kg / m2 and under had a partial fat necrosis rate of 11.4 percent ( 10 of 88 patients ) , whereas two of 19 patients ( 10.5 percent ) with an index of greater than 30 kg / m2 had partial fat necrosis of their flap ( not significant ) . - pubmed
The rate of non - flap - related complications , such as deep venous thrombosis and pulmonary embolism , was 8 percent ( seven of 88 patients ) for those with a body mass index of less than 30 kg / m2 and 31.6 percent ( six of 19 patients ) for those with an index greater than 30 kg / m2 ( p = 0.0112 ) . - pubmed
After above 10 - day treatment , all the mice were killed and the tumor body was taken out and weighed to calculate the inhibiting rates on tumor . - pubmed
RESULT : ( DFVP1 plus small dose of CTX obviously enhanced the inhibiting rate of CTX on tumor in the mice inoculated with S180 cells . - pubmed
Incidence of chronic pain in patients with end - stage renal disease on dialysis . - pubmed
A semiquantitative assessment of myocyte damage / inflammation ( grading ) as well as of fibrosis ( staging ) is indicated , thus providing histopathological diagnosis useful to the clinician for more appropriate patient risk stratification and for the application of new therapies . - pubmed
A cDNA microarray containing 9600 cDNA spots was used to investigate differential expression of human genes in oocyte , 4 - cell and 8 - cell embryos . - pubmed
Most common pathogens of the pyogenic liver abscess are Escherichia coli , Klebsiella pneumoniae , Bacteroides , Enterococci , Streptococci , and Staphylococci . - pubmed
The patient was 52 years - old man who had an episode of intermittent fever , chills and epigastric pain for 2 weeks . - pubmed
[ Present situation and future perspectives of the epidemic of HIV and AIDS in Spain ] . - pubmed
The rate of diagnoses of HIV has fallen in both the indigenous population and immigrants ; however , demographic changes have meant an increase in the percentage of HIV diagnoses in immigrants . - pubmed
In homosexual men there have been descriptions of a recent increase in the incidence of syphilis and gonococcus , which are a warning of possible increases in the transmission of HIV in this group . - pubmed
One third of the people who developed AIDS in 2004 had not until then been diagnosed with HIV , which prevented starting the antiretroviral treatment in time . - pubmed
[ Hemodynamic effects of levosimendan compared with dobutamine in patients with low cardiac output after cardiac surgery ] . - pubmed
However , experience with levosimendan in patients with reduced cardiac output following cardiopulmonary bypass is limited . - pubmed
METHODS : Forty - one patients who had low cardiac output after cardiopulmonary bypass were randomly assigned to dobutamine ( n=20 ) , 24 - hour infusion of 7.5 microg / kg per min , or levosimendan ( n=21 ) , at a loading dose of 12 microg / kg followed by 24 - hour infusion of 0.2 microg / kg per min . - pubmed
Image relocation with prisms in patients with age - related macular degeneration . - pubmed
BACKGROUND : To determine the benefits of image relocation ( IR ) with prisms in patients with age - related macular degeneration ( AMD ) . - pubmed
METHODS : This was a retrospective comparative interventional case series of 100 patients with AMD and 5 years of available follow - up records . - pubmed
The present paper describes 22 cases of chromoblastomycosis ( CBM ) caused by Cladophialophora carrionii in children and adolescents ( 2 - 19 years old ) . - pubmed
The patients were thus able to avoid the evolution of the chronic , deforming and incapacitation clinical manifestations associated with CBM . - pubmed
Data from patients with noncancer or cancer pain treated with TD buprenorphine or TD fentanyl for at least 3 months between May 2002 and April 2005 were analyzed . - pubmed
RESULTS : In total , 631 patients with noncancer pain and 605 patients with cancer pain were included in the analysis ( 782 women , 454 men ; mean age , 76.3 years [ range , 29 - 100 years ] ) . - pubmed
A significantly larger proportion of patients receiving TD buprenorphine had stable dosages over the entire treatment period compared with patients receiving TD fentanyl ( noncancer groups : 56.9 % vs 41.6 % ; cancer groups : 50.0 % vs 26.2 % [ both , P & lt ; 0.05 ] ) . - pubmed
Compared with TD buprenorphine , the proportion of patients with alternating dosage changes was significantly greater in patients receiving TD fentanyl ( noncancer groups : 22.7 % vs 13.1 % ; cancer groups : 30.6 % vs 11.8 % [ both , P & lt ; 0.05 ] ) . - pubmed
Herein , we report a rare case of actinomycosis presenting as a vocal cord nodule in a healthy 21 - year - old man who was not immunocompromised and had no other known medical disease . - pubmed
CONCLUSIONS : The high rates of infection found in the populations studied presume a high risk of transmission , making it a priority to intervene in these groups to prevent the spread of HIV and STI . - pubmed
Active surveillance for selected patients with renal masses : updated results with long - term follow - up . - pubmed
Patients elected observation because of age , comorbidity , solitary kidney , or bilateral renal masses . - pubmed
A small but non - negligible risk of developing metastatic disease exists in this patient population . - pubmed
With the recent advances in molecular biology and the ever - expanding understanding of trauma pathophysiology , immunomonitoring in trauma patients attempts to characterise and quantify novel molecules in order to predict patients at risk . - pubmed
This review article assesses the existing evidence on the biomarkers of endothelial injury and their potential utility as quantification parameters of endothelial dysfunction in trauma patients . - pubmed
Body balance in patients with systemic vertigo after rehabilitation exercise . - pubmed
Physiotherapeutic procedures were carried out in a group of 12 people , aged 25 - 60 years suffering from vertigo . - pubmed
Patients with vertigo underwent a month - long therapy , which included : exercise of motor - visual coordination on a posturographic platform and balance exercise , which consisted of repeated visual , vestibular , and somatosensory stimulation for conscious postural control . - pubmed
Altered red cell membrane compositions related to functional vitamin B ( 12 ) deficiency manifested by elevated urine methylmalonic acid concentrations in patients with schizophrenia . - pubmed
BACKGROUND : Abnormal cell membrane composition and functional cobalamin ( vitamin B ( 12 ) ) deficiency was reported in schizophrenic individuals . - pubmed
We aimed to investigate the relationship between cobalamin state and cell membrane composition in patients with schizophrenia . - pubmed
METHODS : Malondialdehyde ( MDA ) , cholesterol , and phospholipid classes in the erythrocyte membranes of 18 schizophrenic and 20 healthy individuals of the same age and sex distribution were determined . - pubmed
In schizophrenic individuals , uMMA concentrations have a significant positive correlation with membrane MDA and a negative correlation with membrane cholesterol concentrations ( P<0.05 ) . - pubmed
CONCLUSION : Our present findings suggest that , functional vitamin B ( 12 ) deficiency representing itself by MMA elevations in schizophrenic individuals could damage cell membrane . - pubmed
RATIONALE : Laboratory animal and human models of drug self - administration are used to evaluate potential pharmacotherapies for drug abuse , yet the utility of these models in predicting clinically useful medications is variable . - pubmed
CONCLUSIONS : The self - administration model has reliably identified medications to treat opioid dependence , and the recent data with modafinil suggest that the human laboratory model also identifies medications to treat cocaine dependence . - pubmed
" Torsade de pointes " during amiodarone infusion in a cirrhotic woman with a prolonged QT interval . - pubmed
We describe an interesting case of a woman with decompensated cirrhosis , ischaemic heart disease and prolonged QT interval , who developed a new - onset atrial fibrillation . - pubmed
Our report underlines that the potential harmfulness of a prolonged QT interval in cirrhotic patients is currently not perceived in its entirety , so that various categories of drugs affecting ventricular repolarization are rather thoughtlessly used in clinical practice without monitoring the QT interval . - pubmed
Thus , amiodarone should be avoided , if possible , or used with extreme care in arrhythmic patients with advanced liver disease . - pubmed
Moreover , beta - blockers may be considered the first - line treatment for rate - control during supraventricular tachyarrhythmias in cirrhotic patients with delayed repolarization . - pubmed
RESULTS : Nine patients presented with ocular symptoms and one patient experienced pulsatile tinnitus . - pubmed
In patients with penile cancer health - related quality of life is closely related to organ - sparing surgery . - pubmed
MBL was absent in the lavage of all 7 children without lung infection but present in 62 % ( 8/13 ) of those with acute pneumonia / pneumonitis , 23 % ( 5/22 ) with recurrent respiratory tract infections , 17 % ( 1/6 ) with primary ciliary dyskinesia and 8 % ( 3/37 ) with CF ( p<0.01 ) . - pubmed
Children with acute pneumonia / pneumonitis had significantly higher levels than those in the other groups . - pubmed
OBJECTIVE : Approximately 50 % of patients with depression report symptoms of pain , yet the clinical and biological mechanisms underlying this association remain unclear . - pubmed
Similar to the general population , reported associations between obesity and insulin resistance in chronic uremia support a role of adipose tissue and altered adipokine profiles in insulin resistance in obese chronic kidney disease patients . - pubmed
MATERIALS AND METHODS : Fifteen patients ( geometric mean 47 years , range 8 - 69 years ) with different types of inflammatory arthritis of the finger or wrist joints participated in the study . - pubmed
OBJECTIVE : To develop and validate a modified index for assessing the radiologic axial involvement in psoriatic arthritis ( PsA ) in a group of patients with established disease . - pubmed
A 23 - year - old man had been treated for repeated pneumonia from the age of 16 . - pubmed
Placental and fetal hemodynamics after labetalol or pindolol in a sheep model of increased placental vascular resistance and maternal hypertension . - pubmed
We investigated the effects of labetalol and pindolol on uterine , placental , and fetal hemodynamics following norepinephrine - induced maternal hypertension in a sheep model of increased placental vascular resistance . - pubmed
The in vivo effect of the antibody was investigated in a rabbit model of trabeculectomy by measuring the intraocular pressure ( IOP ) and bleb area , and by immunohistological analysis of angiogenesis , inflammation , and fibrosis . - pubmed
MATERIALS AND METHODS : Bladder ischemia was induced by ligation of bilateral vesical arteries in female rats . - pubmed
In diabetic rats , the rate of leukocyte transmigration into the retinal tissues of live animals was significantly increased , as determined by AOLS . - pubmed
However , firm adhesion of leukocytes in diabetic animals treated with the inhibitor did not differ significantly from vehicle - treated diabetic controls . - pubmed
Genomic imprinting disorders in humans : a mini - review . - pubmed
The first report in humans occurred in Prader - Willi syndrome due to a paternal deletion of chromosome 15 or uniparental disomy 15 ( both chromosome 15s from only one parent ) and similar genetic disturbances were reported later in Angelman syndrome . - pubmed
Immunization of volunteers by the bite of mosquitoes carrying radiation - attenuated Plasmodium falciparum sporozoites protects greater than 90 % of such volunteers against malaria , if adequate numbers of immunizing biting sessions and sporozoite - infected mosquitoes are used . - pubmed
We tested the efficacy and toxicity of a chemotherapy protocol consisting of gemcitabine , 5 - fluorouracil ( 5 - FU ) and leucovorin in patients with inoperable or metastatic pancreatic cancer , which was shown to improve median survival in a small phase II trial . - pubmed
PATIENTS AND METHODS : Patients older than 18 years of age with histologically or cytologically confirmed adenocarcinoma of the pancreas and bidimensionally measurable disease , and who were chemotherapy- and radiotherapy - naive , were treated with a chemotherapy protocol consisting of gemcitabine 1250 mg / m2 on day 1 , 5 - FU 450 mg / m2 and leucovorin 100 mg / m2 on days 1 - 3 . - pubmed
RESULTS : In an - intention - to - treat analysis , of 37 patients with pancreatic cancer ( 27 males , 10 females ) ( 67.6 % stage IVb ) there were 7 ( 18.9 % ) objective partial responses ( 95 % confidence interval , 8.33 % to 29 ) , 14 ( 37.8 % ) patients had stable disease and 16 ( 43.2 % ) had progressive disease . - pubmed
CONCLUSION : Despite our poor survival data , the combination of gemcitabine with 5 -/ FU and leucovorin is an active and well - tolerated regimen in patients with pancreatic cancer that merits further evaluation in prospective randomized studies . - pubmed
Trajectories of fatigue in patients with breast cancer before , during , and after radiation therapy . - pubmed
METHODS : Seventy - three women with breast cancer completed questionnaires that assessed sleep disturbance , depression , anxiety , and pain prior to the initiation of RT and the Lee Fatigue Scale , over 6 months . - pubmed
The relationship between chronic volume overload and elevated blood pressure in hemodialysis patients : use of bioimpedance provides a different perspective from echocardiography and biomarker methodologies . - pubmed
BACKGROUND : Chronic volume overload is very frequent in hemodialysis ( HD ) patients and is directly associated with hypertension , increased arterial stiffness , left ventricular hypertrophy ( LVH ) , heart failure and ultimately with higher mortality and morbidity . - pubmed
Forty - five percent of patients ( group A ) had a reasonable control of BP and volume ( SBP & lt ; 150 mmHg and RTH & lt ; 15 % ) , 29.3 % ( group B ) were classified as hypertensive ( SBP & gt ; 150 mmHg and RTH & lt ; 15 % ) , 16.7 % ( group C ) had high blood pressure and marked volume expansion , ( SBP & gt ; 150 mmHg and RTH & gt ; 15 % ) , while 9 % ( group D ) had SBP & lt ; 150 mmHg despite RTH & gt ; 15 % . - pubmed
RESULTS : The analysis included 110 patients , 60 ( 55 % ) with grade one or greater rash and 47 ( 43 % ) with grade one or greater diarrhoea . - pubmed
METHODS : Nine Sprague - Dawley ( SD ) male rats were randomly divided into SCI , normal and sham - operation control groups . - pubmed
In this study , we report a novel 3 - Tesla RT -RI based porcine RF ablation model and visualization of lesion formation in the atrium during RF energy delivery . - pubmed
In recent years , study of rare bone diseases has led to the identification of signalling pathways that regulate bone formation and provided targets for the development of novel therapeutic agents to stimulate bone formation in patients with osteoporosis . - pubmed
Blood pressure effects of naproxcinod in hypertensive patients . - pubmed
The blood pressure ( BP ) effects of naproxcinod and naproxen were assessed in an 8 - week , double - blind , crossover study in 131 hypertensive patients aged 50 to 74 years . - pubmed
Naproxcinod may be a beneficial alternative for patients with osteoarthritis requiring nonsteroidal anti - inflammatory drugs . - pubmed
We report three cases of bullous pemphigoid in adults younger than 50 years old , discussing the clinical characteristics of the disease in younger patients . - pubmed
METHODS : Patients included in the study were divided in two separate groups : 30 patients had chronic wounds and 24 patients had superficial traumatic wounds . - pubmed
The lesion area and the rate of re - epithelialization were calculated , considering the time span and monitoring the patients for clinical signs of wound infection . - pubmed
Patients satisfaction and compliance were evaluated by a questionnaire aimed at assessing pain and ease of use of the device . - pubmed
A single - arm pilot phase II study of gefitinib and irinotecan in children with newly diagnosed high - risk neuroblastoma . - pubmed
Five patients had partial responses ; 9 others had a 23%-60 % decrease in primary tumor volume and/or improved MIBG scans or decreased bone or bone marrow tumor burden . - pubmed
Several papers reported about patients with cushingoid appearance , suggesting an adrenal suppression related to clobetasol systemic absorption after local application . - pubmed
Traditional medicinal uses attributed to Ardisia include alleviation of liver cancer , swelling , rheumatism , earache , cough , fever , diarrhea , broken bones , dysmenorrhea , respiratory tract infections , traumatic injuries , inflammation , pain , snake and insect bites , birth complications and to improve general blood circulation , among others . - pubmed
Traumatic experiences that occur during adolescence can render individuals vulnerable to mood and anxiety disorders . - pubmed
A rat pain model of facial cancer . - pubmed
Although several cancer pain animal models have been reported , these models have focused on the sciatic nerve areas . - pubmed
To understand the mechanisms of pain associated with orofacial cancer , we recently created a rat facial cancer model by inoculation of cancer cells into the vibrissal pad . - pubmed
This model provides mechanical allodynia , thermal hyperalgesia , and feeding disorder characteristics , similar to orofacial cancer patients . - pubmed
In this chapter , we describe in detail the generation of a facial cancer pain model of rats by inoculation of Walker carcinosarcoma 256B cells . - pubmed
TRUS - guided seminal vesicle aspiration can be used in conjunction with TRUS to confirm the diagnosis pre - operatively , especially in patients with seminal vesicle dilation and a prostatic midline / ejaculatory duct cyst on TRUS . - pubmed
In patients with findings of chronic inflammation , such as ejaculatory duct calcifications and seminal vesicle atrophy/ hypoplasia on TRUS , proximal vasal obstruction or functional EDO should be excluded . - pubmed
Outcomes of mechanical valves in the pulmonic position in patients with congenital heart disease over a 20 - year period . - pubmed
BACKGROUND : Homografts or bioprosthetic valves have been preferred in the pulmonic position in patients with congenital heart disease . - pubmed
The dried roots of Euphorbia kansui ( kansui ) have been used for centuries in China as a herbal medicine for edema , ascites , and asthma . - pubmed
Most ingenane - type diterpenoids and 8 - ene-7 - one triterpenoids ( 5 - 11 ) exhibited a relatively lower IC(50 ) value ; therefore , these compounds had stronger cytotoxicity against human normal cell lines L - O2 and GES-1 with dose - dependent relationships . - pubmed
We report a case of a 68 - year - old female patient who developed hemophagocytic lymphohistiocytosis ( HLH ) secondary to peripheral T - cell lymphoma ( PTCL ) not otherwise specified ( NOS ) that developed in the setting of treatment - resistant B - cell small lymphocytic lymphoma / chronic lymphocytic leukemia ( SLL / CLL ) . - pubmed
The patient 's B - cell lymphoma had a good initial response to chemotherapy for 4 years , after which it became less responsive and was thought to have undergone transition to a higher - grade lymphoma . - pubmed
Different regimens of chemoradiotherapy were then tried with modest response until the patient presented 3 years later with signs and symptoms of HLH . - pubmed
RESULTS : Four hundred seventeen PD patients returned the questionnaire , with RBD scores > = 6 in 172 patients . - pubmed
These patients had longer disease duration and lower activity of daily living scores , as well as more frequent nighttime awakenings and hallucinations than PD patients with RBDSQ scores < 6 . - pubmed
Herpes simplex encephalitis ( HSE ) is a rare but severe complication of frequent and mostly benign infection with herpes simplex virus ( HSV ) . - pubmed
Twenty - seven patients ( 71.1 % ) were neutropenic at the onset of infection . - pubmed
In immunocompromised hematology - oncology patients with severe sepsis , S. - pubmed
This allows for future autotransplantation if a patient becomes permanently hypocalcemic after surgery . - pubmed
Three of the 4 patients remained hypoparathyroid after this procedure . - pubmed
A Gram - reaction - negative , aerobic , motile by one polar flagellum , yellow - pigmented , rod - shaped bacterium , designated strain THG - B117(T ) , was isolated from soil of a cornus fruit field of Hoengseong province in South Korea and its taxonomic position was investigated by a polyphasic study . - pubmed
DNA - DNA hybridization experiments showed that DNA relatedness between strain THG - B117(T ) and its phylogenetically closest neighbours was below 45.1 % . - pubmed
The G+C content of the genomic DNA of strain THG - B117(T ) was 64.8 mol% . - pubmed
is proposed , with the type strain THG - B117(T ) ( = KACC 16981(T ) = JCM 18747(T ) ) . - pubmed
Prospective evaluation of intra - observer variability of the hydronephrosis index in sonographic examination of 44 patients with acute renal colic . - pubmed
A historical perspective on the early treatment of night blindness and the use of dubious and unproven treatment strategies for patients with retinitis pigmentosa . - pubmed
The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease . - pubmed
We present a case of accessory scrotum associated with lipomatous hamartoma in a 46 - year - old man who was born with a perineal mass . - pubmed
A 29 - month - old girl presented with seizure and a brain magnetic resonance image revealed a huge heterogeneous mass in the left lateral ventricle . - pubmed
Salmonella enterica serovar Typhi is associated with a disseminated febrile illness in humans , termed typhoid fever , while Salmonella enterica serovar Typhimurium causes localized gastroenteritis in immunocompetent individuals . - pubmed
Clinical application of transient elastography in patients with chronic viral hepatitis receiving antiviral treatment . - pubmed
Accurate evaluation of the degree of liver fibrosis in patients with chronic liver diseases ( CLD ) is crucial , as liver fibrosis is important in determining the prognosis of liver diseases . - pubmed
In the past few years , the role of TE in monitoring liver stiffness and determining prognosis in patients with chronic hepatitis B ( CHB ) or chronic hepatitis C ( CHC ) who are undergoing antiviral treatment has been investigated . - pubmed
In patients with CHC , TE can be used to monitor potential regression of liver fibrosis after antiviral treatment and may predict the treatment outcome of CHC . - pubmed
In addition , TE is an adjunct tool for distinguishing inactive hepatitis B virus carriers from patients with chronic active hepatitis . - pubmed
METHODS : Data were from the Multi - Ethnic Study of Atherosclerosis ( MESA ) , a population - based cohort study of 6749 adults , aged 45 to 84 years and free of clinical cardiovascular disease at baseline , conducted at 6 US sites . - pubmed
INTRODUCTION : There are little data about patients with cardiogenic shock ( CS ) who survive the early phase of acute myocardial infarction ( AMI ) . - pubmed
METHODS : We analyzed 5 - year follow - up data from the French registry of Acute ST - elevation and non - ST - elevation Myocardial Infarction ( FAST - MI ) 2005 registry , a nationwide French survey including consecutive patients admitted for ST or non - ST - elevation AMI at the end of 2005 in 223 institutions . - pubmed
RESULTS : Of 3670 patients enrolled , shock occurred in 224 ( 6.1 % ) , and 3411 survived beyond 30 days or hospital discharge , including 99 ( 2.9 % ) with shock . - pubmed
CONCLUSIONS : In patients surviving the early phase of AMI , CS at the initial stage carries an increased risk of death up to one year after the acute event . - pubmed
Beyond one year , however , mortality is similar to that of patients without shock . - pubmed
Fluoxetine - induced tardive dyskinesia in a patient with Parkinson ' s disease . - pubmed
We report two cases of elderly patients who were diagnosed with disc fracture of the TMJ based on MRI , and we review related reports . - pubmed
On physical examination , an incomplete bite and mild joint pain were observed on the affected side in both patients . - pubmed
The first line of treatment for individuals with prediabetes is lifestyle modification , including diet and exercise . - pubmed
The poor prognosis of patients with GBM underscores the clear and urgent need for more precise and potent therapies . - pubmed
BACKGROUND : Dengue viruses ( DENVs ) are mosquito - borne viruses which can cause disease ranging from mild fever to severe dengue infection . - pubmed
Strains from at least two genotypes of DENV-1 ( Asia and America / Africa genotypes ) have been circulating in western Saudi Arabia until 2006 . - pubmed
FINDINGS : Here , we report the isolation and the first complete genome sequence of a DENV-1 strain ( DENV-1 - Jeddah-1 - 2011 ) isolated from a patient from Jeddah , Saudi Arabia in 2011 . - pubmed
Whole genome sequence alignment and phylogenetic analysis showed high similarity between DENV-1 - Jeddah-1 - 2011 strain and D1 / H / IMTSSA / 98 / 606 isolate ( Asian genotype ) reported from Djibouti in 1998 . - pubmed
Our aim was to evaluate the results of combining endovascular treatment of SFA with distal vein bypass in patients with critical limb ischemia ( CLI ) and great tissue loss or in the cases where the below - knee endoluminal techniques alone were unable to salvage limbs . - pubmed
CONCLUSION : The endovascular treatment of SFA associated with surgical distal vein bypass is a useful and effective strategy in patients with severe lower extremity arterial disease . - pubmed
This paper reviews the nonotogenic causes of persisting dizziness , the possible mechanisms , and the pathophysiology , as a framework for patient management and for future research . - pubmed
The experiment was performed on 30 female Polish Large White pigs , aged 2 months , with body weight of 15 - 18 kg , divided into two groups : control ( C , n = 15 ) and experimental ( Z , n = 15 ) . - pubmed
Antiretroviral Effects on Host Lipoproteins Are Associated With Changes in Hepatitis C Virus ( HCV ) RNA Levels in Human Immunodeficiency Virus / HCV Coinfected Individuals . - pubmed
We evaluated the impact of antiretroviral - induced dyslipidemia on hepatitis C virus ( HCV ) biogenesis in human immunodeficiency virus ( HIV )/ HCV coinfected patients . - pubmed
This study used serum samples from antiretroviral - naive HIV / HCV patients initiating their first regimen as part of AIDS Clinical Trials Group study protocols ( A5142 , A5202 ) . - pubmed
Off - target lipogenic changes need to be considered in the context of liver and other metabolic disease in HIV / HCV patients . - pubmed
Short communication : use of the BetaStar Plus assay for detection of ceftiofur antimicrobial residues in milk from individual cows following intramammary treatment for mastitis . - pubmed
The objective of this study was to evaluate the effectiveness of a lateral - flow immunodiagnostic assay ( BetaStar Plus , Neogen Corp. , Lansing , MI ) in detecting ceftiofur residues in milk from individual cows treated for mastitis . - pubmed
Forty - five dairy cows with clinical mastitis from 4 dairy farms were enrolled and treated intramammary with 125 mg of ceftiofur hydrochloride ( Spectramast LC , Zoetis , Madison , NJ ) according to the manufacturer 's label recommendation . - pubmed
The BetaStar Plus assay could be useful for detecting ceftiofur residues in milk from individual cows following intramammary treatment for mastitis before the milk is shipped for processing . - pubmed
In this study , we isolated primary pancreatic fibroblasts from wild type C57 mice and co - cultured them with pancreatic cancer cell lines , BxPC-3 and SW1990 , and observed the conversion from NF to CAF , or at least CAF - like cells . - pubmed
FG-4592 administration also improved recovery and increased the survival of neurons in spinal cord lesions in the mice model . - pubmed
While the introduction of anti - tVEGF agents has significantly improved visual outcomes of patients with DR , unpredictable response , largely due to genetic polymorphisms , appears to be a challenge with this therapy . - pubmed
With advances in identification of various genetic biomarkers , novel therapeutic strategies consisting of gene transfer are being developed and tested for patients with DR . - pubmed
Oral steroids for the resolution of otitis media with effusion ( OME ) in children ( OSTRICH ): study protocol for a randomised controlled trial . - pubmed
BACKGROUND : Otitis media with effusion ( OME ) is an accumulation of fluid in the middle ear affecting about 80 % of children by the age of 4 years . - pubmed
Children with persistent hearing loss associated with OME are usually offered hearing aids or insertion of ventilation tubes through the tympanic membrane . - pubmed
The aim of the Oral Steroids for the Resolution of Otitis Media with Effusion in Children ( OSTRICH ) trial is to determine if a short course of oral steroids improves the hearing of children with OME in the short and longer term . - pubmed
A trained clinician seeks informed consent from parents of children with symptoms for at least 3 months that are attributable to OME and with confirmed bilateral hearing loss at study entry . - pubmed
Drugs for preventing red blood cell dehydration in people with sickle cell disease . - pubmed
AUTHORS ' CONCLUSIONS : While the results of zinc for reducing sickle - related crises are encouraging , larger and longer - term multicenter studies are needed to evaluate the effectiveness of this therapy for people with sickle cell disease . - pubmed
MATERIAL AND METHODS : The files of 38 patients , with recurrent laryngeal nerve injury following thyroidectomy , that were referred to Istanbul Forensic Medicine Institute with request of expert opinion between 2008 - 2012 were retrospectively investigated . - pubmed
Nineteen patients had unilateral , and 19 patients had bilateral nerve damage . - pubmed
PURPOSE : Dyslexia is one of the most common learning disabilities affecting millions of people worldwide . - pubmed
Thirteen children with dyslexia and 13 sex- and age- matched controls performed three psychophysical tasks . - pubmed
CONCLUSION : We may suggest that dyslexic subjects might suffer from both magnocellular and parvocellular deficits . - pubmed
MATERIALS AND METHODS : Hero 's modified Di Chiro classification differentiated four types of spinal AVMs on digital subtraction angiogram ( DSA ) in 74 patients : I. - pubmed
A patient with extradural AVM remained unclassified . - pubmed
The present study reports the case of a male patient presenting with multiple bilateral cortical kidney cysts at the age of 4 years , at which time the kidneys were of normal size and function . - pubmed
Most brands of soy milk tested in our study had fluoride content below the optimal daily intake but brands containing tea powder extract if consumed by children may increase their risk for fluorosis . - pubmed
Guar gum as a new antimicrobial peptide delivery system against diabetic foot ulcers Staphylococcus aureus isolates . - pubmed
Diabetic patients frequently develop diabetic foot ulcers ( DFUs ) , particularly those patients vulnerable to Staphylococcus aureus opportunistic infections . - pubmed
Both were patients with inflammatory bowel disease [ IBD ] , treated successfully with adalimumab . - pubmed
Vigilance is appropriate when patients present with symptoms compatible with sarcoidosis . - pubmed
Temporomandibular disorders and quality of life among 12 - year - old schoolchildren . - pubmed
Although its blockade has effective anticancer effects in experimental models , it may lead to fatal arrhythmias in humans . - pubmed
Extensive Usutu virus activity in the Netherlands in 2016 underlines the need to monitor mosquito activity and mosquito - borne infections in 2017 and beyond . - pubmed
High - sucrose - induced maternal obesity disrupts ovarian function and decreases fertility in Drosophila melanogaster . - pubmed
Using our previously reported Drosophila high - sucrose maternal obesity model , we sought to determine how excess dietary sucrose impacted the ovary . - pubmed
PURPOSE : The purpose of this study was to evaluate the clinical features and the long - term outcomes of primary conjunctival marginal zone B - cell lymphoma ( MZBCL ) patients who were treated with radiation therapy ( RT ) . - pubmed
MATERIALS AND METHODS : Retrospective data of 79 patients with 121 primary conjunctival MZBCL lesions were collected from January 1 , 2001 till June 30 , 2014 . - pubmed
CONCLUSION : 26 Gy 's RT was highly effective and safe , with the use of lens - shielding device , in treating patients with primary conjunctival MZBCL . - pubmed
For women age & lt;45 years allocated 5 years of tamoxifen , the risk of contralateral breast cancer is halved over 15 years . - pubmed
Premenopausal women with ER + ve HER2 - negative breast cancer with high - risk features can derive a meaningful improvement in 5 - year invasive breast cancer - free interval with exemestane plus ovarian suppression , as an alternative to tamoxifen . - pubmed
Phosphoproteomic Analysis Identifies Signaling Pathways Regulated by Curcumin in Human Colon Cancer Cells . - pubmed
Quantitative comparison of the spreading and invasion of radial growth phase and metastatic melanoma cells in a three - dimensional human skin equivalent model . - pubmed
RESULTS : Twenty patients who later developed DCI were included , and twenty - eight patients without DCI were identified for comparison . - pubmed
XeCT may be potentially helpful in managing poor - grade SAH patients . - pubmed
Hepatoprotective effect of calculus bovis sativus on nonalcoholic fatty liver disease in mice by inhibiting oxidative stress and apoptosis of hepatocytes . - pubmed
In Asian countries , CB Sativus ( CBS ) , an ideal substitute for natural CB , is presently extensively used for long - term treatment of chronic liver diseases . - pubmed
The NAFLD model was established in C57BL/6 mice by exclusively feeding fluids containing 30 % fructose for 8 consecutive weeks . - pubmed
Histopathological examination showed that liver steatosis and injury were significantly reduced in CBS - treated mice . - pubmed
In conclusion , CBS treatment exerted therapeutic effects in the liver of mice with NAFLD , which may be associated with amelioration of metabolic disorders , enhanced antioxidant effects , and alleviation of apoptosis . - pubmed
We herein present the case of a 23 - year - old man with poorly controlled T1DM who had liver dysfunction . - pubmed
In this case , the improvement of hyperglycemia , not HbA1c , resulted in the improvement of the patient 's liver function . - pubmed
DESIGN : Observational cohort study of subarachnoid hemorrhage patients ( n = 133 ) admitted to rehabilitation ( n = 49 ) , discharged home ( n = 52 ) , or died before discharge ( n = 10 ) . - pubmed
Since the introduction of direct - acting antivirals ( DAAs ) , the outcomes of hepatitis C ( HCV ) treatment have shown an improvement in cure rates with minimal side effects . - pubmed
Species differences in renal drug transporters continue to plague drug development with animal models failing to adequately predict renal drug toxicity . - pubmed
For example , adefovir , a renally excreted antiviral drug , failed clinical studies for human immunodeficiency virus due to pronounced nephrotoxicity in humans . - pubmed
Developmental coordination disorder ( DCD ) is a neurodevelopmental disorder affecting 5 - 6 % of children that is characterized by deficits in motor skills . - pubmed
Studies show that children with DCD have motor timing and sensorimotor timing deficits . - pubmed
This idea is consistent with evidence from several domains , ( 1 ) motor - related brain regions are often involved in auditory timing process ; ( 2 ) DCD has high comorbidity with dyslexia and attention deficit hyperactivity , which are known to be associated with auditory timing deficits ; ( 3 ) a few studies report deficits in auditory - motor timing among children with DCD ; and ( 4 ) our preliminary behavioral and neuroimaging results show that children with DCD at age 6 and 7 have deficits in auditory time discrimination compared to typically developing children . - pubmed
PURPOSE : The aim of this pilot study was to evaluate the effect of a multicomponent balance and resistance training intervention on physical function , balance , and falls in older ( & gt;=65 years ) community - dwelling heart failure ( HF ) patients . - pubmed
CONCLUSIONS : A supervised group session intervention can increase mobility and gait and reduce fall rate for HF patients . - pubmed
CLINICAL RELEVANCE : This study was designed to improve lower extremity strength , balance , and falls in elderly HF patients , thus reducing costs and improving quality of life for this population . - pubmed
MATERIAL AND METHODS : 76 cases of ameloblastoma were investigated , the average age of the patients was 46 years . - pubmed
PURPOSE : To evaluate the outcome of surgical treatment in patients with type 1 monocular elevation deficiency . - pubmed
METHODS : Patients who were diagnosed as having type 1 monocular elevation deficiency by forced duction test and exaggerated traction test between 2000 and 2016 were retrospectively reviewed . - pubmed
The clinical features of the patients who did not achieve surgical success after inferior rectus recession were determined . - pubmed
The surgical and functional results of contralateral superior rectus recession were evaluated for patients who had residual hypotropia under inferior rectus recession . - pubmed
Ten ( 25.64 % ) patients did not achieve surgical success ( & gt ; 6 PD residual hypotropia ) . - pubmed
CONCLUSIONS : Inferior rectus recession is the first surgical option for patients with type 1 monocular elevation deficiency . - pubmed
Patients undergoing cytotoxic or immunosuppressive therapy for cancer have an established predilection for hepatitis B virus reactivation ; however , the risk associated with newer molecularly targeted agents has not been well investigated . - pubmed
We report the case of a patient who developed hepatitis B virus reactivation while receiving imatinib therapy for gastrointestinal stromal tumor . - pubmed
Imatinib - associated hepatitis B virus reactivation was reported in seven patients with chronic myeloid leukemia , one with desmoid tumor , and one with gastrointestinal stromal tumor . - pubmed
We aim to increase awareness about this possible association and advocate for hepatitis B virus screening prior to imatinib therapy , especially in patients who are at increased risk for chronic hepatitis B virus infection . - pubmed
We queried prehospital databases to identify cases , which included all adult patients ( & gt;= 18 years ) with a prehospital glucose reading of & lt;72mg / dl ( 4.0mmol / L ) and excluded terminally ill and cardiac arrest patients . - pubmed
Successful recovery of associated interstitial nephritis and focal segmental glomerulosclerosis in patients with HCV and HIV treated with sofosbuvir and daclatasvir and revision of literature . - pubmed
In this report , we describe the coexistence of two rare and debated complications of hepatitis C virus ( HCV ) infection : interstitial nephritis , with associated focal glomerulosclerosis , and autoimmune hepatitis , in a 55 - year - old HIV / HCV - coinfected woman . - pubmed
A 24 - year - old patient with anaplastic astrocytoma requiring chemotherapy with temozolomide for 12 cycles as soon as possible with wish for fertility preservation while using a long acting etonogestrel birth control implant presented in our unit for fertility preservation in May 2017 . - pubmed
IVM could be a possibility for fertility preservation in patients with polycystic ovaries when no time is available for stimulation for conventional in vitro fertilization . - pubmed
Method : We recruited 22 patients under 15 years of age with cough lasting longer than 4 weeks ( group 1 ) , 7 controls with allergic rhinitis ( group 2 ) , and 10 controls without respiratory symptoms ( group 3 ) . - pubmed
Results : Group 1A ( cough with clinical bacterial sinusitis n = 10 ): Eight ( 80 % ) patients had bacterial sinusitis associated with dominant potential pathogenic bacteria ( PPB ): Streptococcus pneumoniae , Haemophilus influenzae , and Moraxella catarrhalis . - pubmed
Delayed febrile response with bloodstream infections in patients with continuous - flow left ventricular assist devices . - pubmed
We observed 59 BSIs in LVAD patients and 45 BSIs in controls . - pubmed
Group I patients showed better improvement in terms of functional impairment ( Inability Walking Scale ) , reported pain ( visual analogue scale ) , and daily intake of etoricoxib 60 mg . - pubmed
We also investigated the impact of serum collected from HFD / CD pregnant rats on CD embryonic development in whole - embryo cultures . - pubmed
These findings suggest that metabolic disturbances in HFD pregnant rats have profound adverse developmental effects in the offspring . - pubmed
To investigate the use of a corneal impression membrane ( CIM ) for the detection of herpes simplex virus type 1 ( HSV-1 ) in suspected herpes simplex keratitis ( HSK).Methodology . - pubmed
In suspected HSK , a CIM is a useful alternative to a swab and more likely to detect the presence of HSV-1 . - pubmed
We aimed to investigate the effects of DAA - therapy on liver inflammation , fibrosis , metabolic function and cognitive function and the time course in CHC patients with advanced liver disease . - pubmed
Seventy - one CHC patients with advanced liver disease were studied before , during , and one year after successful sofosbuvir - based DAA - therapy . - pubmed
SUBJECTS / METHODS : This cross - sectional study involved 95 ( 45 had MA and 50 had no MA ) patients with type 2 diabetes mellitus ( DM ) without DR and 91 age- and gender - matched non - diabetic controls . - pubmed
However , diabetic patients ( n = 95 ) had significantly thinner inferior - temporal peripapillary retinal nerve fibre layer ( RNFL ) ( p = 0.042 ) than in the controls ( n = 91 ) . - pubmed
However , 3 mm - nasal , temporal and superior perifoveal thicknesses were significantly lower in patients with DM duration over 10 years ( p & lt ; 0.05 ) . - pubmed
CONCLUSIONS : In diabetic patients without DR , peripapillary inferior - temporal RNFL thinning might be an early sign of neuroretinal degeneration and it seems to be independent from vascular endothelial damage ( MA ) . - pubmed
METHODS : In a 2017 cross - sectional study of rectal STI screening and HIV prevention , a convenience sample of MSM recruited from community venues in Lima completed a survey of demographic characteristics and sexual risk behavior with their three most recent partners . - pubmed
Etiology for airway stenosis in all patients of study group was intubation injury . - pubmed
METHODS : A randomized controlled trial targeting Hiroshima University students was performed to assess the plaque removal efficacy of polybutylene terephthalate ( PBT ) manual toothbrushes . - pubmed
Predictive factors for progression - free survival in non - small cell lung cancer patients receiving nivolumab based on performance status . - pubmed
METHODS : We retrospectively collected pretreatment clinical data of 296 consecutive patients with NSCLC treated with nivolumab . - pubmed
Internet society , internet addiction , and pathological social withdrawal : the chicken and egg dilemma for internet addiction and hikikomori . - pubmed
METHODS : The study included in 59 non - smoker asthma patient ( Exacerbated=25 , Stable=34 ) and 30 healthy volunteers . - pubmed
Patients with > =3 risk factors had more severe pain intensity scores , spent a longer time in severe pain , and wished to have received more pain treatment ( P < 0.001 ) . - pubmed
Conclusions : Patients with > =3 risk factors are at higher risk for poor postoperative acute pain outcome after surgery . - pubmed
The effects of manual manipulation therapy on pain and dysfunction in patients with lumbar spinal stenosis . - pubmed
[ Purpose ] This study investigated the effects of manual manipulation therapy on the pain and dysfunction of patients with lumbar spinal stenosis . - pubmed
[ Participants and Methods ] In this study , 30 patients with chronic back pain were evenly divided into an experimental group , who received manual traction therapy , and a control group , who received intermittent traction therapy . - pubmed
[ Conclusion ] The results of this study suggest that manual manipulation therapy is an effective intervention for treating pain and dysfunction in patients with lumbar spinal stenosis . - pubmed
The patient underwent an initial fine - needle aspiration biopsy ( FNAB ) of an enlarged cervical lymph node followed by surgical excision of the tumor and immunohistochemistry which confirmed the diagnosis . - pubmed
CRAFT - RCT : Randomised controlled trial arm ; To assess treatment for short cervix in women at high risk of preterm birth following a fully dilated caesarean section . - pubmed
Studies on human gingival fibroblasts in vitro revealed that the obtained microparticles did not induce any cytotoxic effects . - pubmed
Clinically , the combination of these two therapies has been used as a treatment for tendon and ligament lesions in horses ; however , there is no scientific evidence supporting this combination of therapies in vivo . - pubmed
Human sparganosis in Arkansas . - pubmed
Long - term ( 48 - hr ) incubations of either the fibroblast strain WI-38 or its SV40 - transformed counterpart , WI-38 - VA13 - 2RA , in growth medium containing 1 micron prostaglandin E1 ( PGE1 ) resulted in a sustained production and release of cyclic AMP from the cells into the medium . - pubmed
Enrichment culture of organisms growing anaerobically in the light in methanol - bicarbonate medium resulted in isolation of strains of Rhodopseudomonas gelatinosa and Rhodopseudomonas acidophila . - pubmed
[ Controlled hypotension with sodium nitroprosside in patients placed in the sitting position during intracranial operations ( author 's transl ) ] . - pubmed
Sodium nitroprusside was used to induce hypotension during continuous neuroleptanalgesia in 11 neurosurgical patients aged between 13 and 53 years placed in the sitting position . - pubmed
No patient had cardiovascular disease . - pubmed
14 patients aged between 18 and 72 years without induced hypotension were used as controls to compare the action of our standardized method of anaesthesia on the same parameters that were also monitored during blood pressure lowering . - pubmed
Cerebral perfusion of these 14 patients with highly elevated intracranial pressure with or without cardiovascular disease already seemed to be threatened by the upright position . - pubmed
Careful monitoring of the patients during and after blood pressure lowering with sodium nitroprusside made it possible to take advantage of the induced hypotension also in strictly - selected neurosurgical patients who have to be operated on in upright position . - pubmed
The postoperative patient is at high risk , as is the patient with cancer or renal failure . - pubmed
Abnormal bleeding was common , but significant hemorrhage occurred only in postoperative patients . - pubmed
Action of phenytoin , ethosuximide and of the carbidopa - L - dopa association in semi - chronic cobalt - induced epilepsy in the rat . - pubmed
A semi - chronic model of cobalt - induced experimental epilepsy in the rat was used to investigate the action of two classic anticonvulsant drugs , phenytoin and ethosuximide . - pubmed
Malignant melanoma has provided an excellent model system for studying crucial events in human tumor development and progression . - pubmed
[ Changes in the intracranial pressure in relation to body posture and their use in the treatment of patients after cranio - cerebral injuries ] . - pubmed
The determination of the best body position in patients after cranio - cerebral injuries was the main subject of the undertaken studies . - pubmed
The positional changes of the intracranial pressure and cerebral perfusion pressure as well as cerebral elasticity were analyzed in 11 patients after cranio - cerebral injuries . - pubmed
The retrospective studies in 157 patients after cranio - cerebral injuries permitted me to compare the results of the classical treatment and the positioning one . - pubmed
The WO-1 strain of Candida albicans is capable of alternating between two highly distinct yeast cell types termed white and opaque ( E. H. A. Rikkerrink , B. - pubmed
Pre- and postoperative evaluation of renal function with five different tests in patients with primary hyperparathyroidism . - pubmed
Renal function was investigated immediately before and 1 year following parathyroidectomy in 19 patients with moderate hypercalcaemia . - pubmed
Glomerular filtration rate , as assessed by plasma creatinine and clearance of both creatinine and 51Cr - EDTA , was normal in most patients , and was little affected by restoration of normocalcaemia . - pubmed
It is concluded that serious renal damage is seldom encountered in present - day HPT patients , but that a treatable decrease in renal concentrating capacity often exists . - pubmed
The purpose of this study was to evaluate the association between anti - phospholipid antibodies and cardiac abnormalities in patients with SLE . - pubmed
PATIENTS AND METHODS : A total of 75 consecutive SLE patients and 60 healthy sex- and age - matched control subjects were evaluated in a case - control study . - pubmed
In 36 patients with mild , moderate and severe aortic stenosis , proved by cardiac catheterization , some electrocardiographic indices for left ventricular hypertrophy were compared with the value of the aortic valve peak systolic gradient . - pubmed
The nocturnal secretion of plasma melatonin was determined under dim to dark conditions in eight patients with prospectively confirmed premenstrual syndrome and in eight age- and menstrual cycle phase - matched normal control subjects . - pubmed
Compared with normal controls , patients with premenstrual syndrome had an earlier ( phase - advanced ) offset of melatonin secretion , which contributed to a shorter secretion duration and a decreased area under the curve . - pubmed
The fact that these patients respond to treatments that affect circadian physiology , such as sleep deprivation and phototherapy , suggests that circadian abnormalities may contribute to the pathogenesis of premenstrual syndrome . - pubmed
Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries . - pubmed
To investigate the potential role of fluid mechanical factors in the localized genesis and development of atherosclerotic lesions in humans , the exact anatomic locations of atherosclerotic lesions and the flow patterns at such sites in left and right human coronary arteries were studied in detail by flow visualization and high - speed cinemicrographic techniques using five isolated , transparent human coronary arterial trees prepared postmortem . - pubmed
The results indicate that the major hemodynamic factors directly related to the localization of atherosclerotic plaques and wall thickenings in the human arterial system are the low fluid velocity and the resultant low shear stress that acts on the vessel wall . - pubmed
There was no significant difference in the pulse frequencies between the patients and controls but the amplitude of both groups of pulses was increased in the PCOS patients . - pubmed
This finding indicates that at least two different genetic defects participate in the formation of the high incidence of spontaneous SCEs in mouse cells . - pubmed
As burn therapy has enabled increasing numbers of patients to survive extensive burns , it is imperative that preservation of function not be ignored and that attention be directed at improved function early in the postburn course . - pubmed
The in situ degradation of rapidly transported proteins in nerve terminals of retinal ganglion cells was studied in pieces of the superior colliculus of the rabbit . - pubmed
[ Leukocyte migration inhibition response in patients with osteoarthrosis deformans ] . - pubmed
[ Ultrastructural study on the effect of pyronaridine on the erythrocytic stages of chloroquine - resistant strain of Plasmodium berghei ] . - pubmed
Emotional alterations of these animals may account for this result , whereas true cognitive deficits are likely to underly the impairment of learning set formation seen in the low lead group . - pubmed
This technique is particularly applicable to elderly , poor risk patients and those patients with villous adenomas which extend so low in the rectum that anterior resection would be difficult or impossible . - pubmed
[ Further investigation to the immunology of murine mammary tumours of the CBA - Bln strain using the colony inhibition tests ( author 's transl ) ] . - pubmed
Language and the education of children with early profound deafness . - pubmed
Evidence for selection of homogeneously staining regions in a human melanoma cell line . - pubmed
Cytogenetic analysis of tumor cells from a human malignant melanoma was performed on both the primary tumor colony - forming cells and a cell line ( HA - A ) established subsequently from the clonogenic population . - pubmed
This represents the first observation of DMs or HSRs in cells from a human malignant melanoma . - pubmed
[ Effects of 10 - hydroxycamptothecin on cAMP and cGMP levels in hepatoma and liver tissue of mice ( author 's transl ) ] . - pubmed
Fever , cough , anal ulcer in a heterosexual man . - pubmed
Prognostic significance of parametrial extension in patients with cervical carcinoma Stages IB , IIA , and IIB . - pubmed
Parametrial extension was evaluated as a prognostic factor in 628 patients with cervical carcinoma treated by radical hysterectomy and pelvic lymphadenectomy at the Aichi Cancer Center in Nagoya , Japan . - pubmed
Vaterite gallstones in a canary ( Serinus canarius ) . - pubmed
[ The effect of short - term lung inflation on the strength of the expiratory reflex in ferrets under normal conditions and in experimental pneumothorax ] . - pubmed
Two hundred and ninety - eight patients attending their general practitioner and requiring treatment for respiratory tract infections were randomly allocated to receive either 250 mg cefaclor 3 - times daily ( intermittent ) or 500 mg amoxycillin 3 - times daily ( continuous ) . - pubmed
A combination therapy consisting of two endolymphic infusions of BCG vaccine and methotrexate followed by remote gamma therapy 10 days after the second infusion was given to 96 patients with stage III esophageal tumors . - pubmed
Kinetic constants of asialoorosomucoid endocytosis comparison between hepatocytes from normal and streptozotocin - diabetic rats . - pubmed
The findings lend support to our hypothesis and observation that the human breast secretes mutagenic and cancer - promoting substances which may have relevance in studies of the etiology of benign breast disease and cancer . - pubmed
Report of a case and review of the literature .. A 13 - year - old boy had obstructive jaundice following several episodes of blunt abdominal trauma . - pubmed
Immediate versus delayed fluid resuscitation in patients with trauma . - pubmed
We describe a 23 - year - old woman without coronary artery disease who had an acute non - Q - wave myocardial infarction and stunned myocardium after receiving topical phenylephrine hydrochloride and cocaine anesthesia for elective nasal septoplasty . - pubmed
Time- and frequency - domain analyses of the signal - averaged ECG in patients with arrhythmogenic right ventricular dysplasia . - pubmed
This study evaluated the usefulness of the frequency - domain analysis of the SAECG in addition to the conventional time - domain analysis for a screening test to detect patients with ARVD . - pubmed
METHODS AND RESULTS : SAECG was recorded by using a bipolar X , Y , and Z lead system in 28 patients with ARVD ( mean age , 38 + /- 13 years ) and 35 age - matched normal subjects ( mean age , 35 + /- 11 years ) . - pubmed
The authors report the occurrence of primary eosinophilic granuloma of the oculomotor nerve without osseous involvement in a 68 - year - old man . - pubmed
A series of 12 patients with tectal plate gliomas , is presented treated by direct surgery . - pubmed
AIM : The purpose of the present study was to know the incidence and risk factors associated with amikacin nephrotoxicity in a cohort of patients form a general medial center . - pubmed
Patients with other risk factors to develop acute renal failure were excluded . - pubmed
RESULTS : Ten patients developed nephrotoxicity ( 9.6 % ) . - pubmed
Two groups of patients were studied : group with stable coronary artery disease and group without the coronary artery disease as well as glycaemia and insulinaemia were studied during the oral glucose tolerance test . - pubmed
A patient with lumbar lipomyelomeningocele with tethered cord , lower thoracic syringomyelia and Chiari I malformation , shown by MRI is reported . - pubmed
Nineteen patients with symptomatic anastomotic leakage after anterior resection were compared with 19 without leakage . - pubmed
The study was carried out for reviewing the hypothesis on the relationship between integrated fish farming ( IFF ) and human influenza A pandemic using study methods of longitudinal epidemiology , ecology and serology . - pubmed
Four rural villages with IFF , non - IFF and non - fish farming , selected from two provinces ( Henan and Shandong of PRC ) were investigated for the status about human influenza A epidemic and infections with human , duck , swine influenaz A viruses in those communities . - pubmed
The results put forward views on that there is no relation between IFF and the increase of incidence rate , infection rate and antibodies level to human influenza A virus . - pubmed
Duck may play an important role in the increase of infection rate to human influenza A viruses among human communities . - pubmed
Pigs seem not to play obvious role in the increase of infection rate to human influenza A viruses among human communities . - pubmed
The ratio of sites with gingivitis to sites with bacterial plaque was calculated ( G / P - ratio ) . - pubmed
OBJECTIVE : To evaluate whether pulmonary embolism ( PE ) , as detected by perfusion lung scan , could be predicted by the ultrasonic ( US ) characteristics of the thrombi in patients with deep venous thrombosis ( DVT ) of the lower limbs . - pubmed
PATIENTS : Ninety - three consecutive patients with DVT and no symptoms of lung involvement ( 52 men , 41 women ; mean age , 67 + /- 17 years ) . - pubmed
The diagnosis of PE ( PIOPED criteria ) was highly probable in 46 % of the patients , intermediate in 15 % , low in 8 % , and very low / normal in 31 % . - pubmed
Low - dose pulse methotrexate has emerged as one of the most frequently used slow - acting , symptom - modifying antirheumatic drugs in patients with rheumatoid arthritis ( RA ) because of its favourable risk - benefit profile . - pubmed
Furthermore , studies in patients with juvenile rheumatoid arthritis provide evidence of age - dependent pharmacokinetics of the drug . - pubmed
Finally , both trimethoprim - sulfamethoxazole ( cotrimoxazole ) and probenecid lead to increased toxicity of methotrexate , and hence should be avoided in patients receiving these drugs . - pubmed
Aortocaval fistulae : a percutaneous model and treatment with stent grafts in sheep . - pubmed
ACFs were successfully created in all animals , with rapid dye shunt through the fistula and a 20 % increase in cardiac pulsations . - pubmed
The method was applied to samples from patients with deficiency in tryptophan metabolism , xanthurenic acid/3 - hydroxy kynurenineuria and showed a striking elevation in serum 8 - methyl ether of xanthurenic acid . - pubmed
There were 9 adverse events ( reaction rate of 8.3 % ) in 6 patients with 5 % NSA and 12 events ( reaction rate 12.1 % ) in 8 patients with Albumex 5 . - pubmed
Apoptosis and proliferation of fibroblasts during postnatal skin development and scleroderma in the tight - skin mouse . - pubmed
Tight - skin ( Tsk ) is a dominant gene mutation that causes a fibrotic skin disease in mice , similar to human scleroderma . - pubmed
Eighteen patients with primary mediastinal germ cell tumour were treated over an 1 - year period ; 9 had seminoma and 9 non - seminoma . - pubmed
All patients with seminoma received consolidation radiotherapy to mediastinum . - pubmed
Three patients with non - seminoma received radiotherapy following partial response . - pubmed
All 9 patients with seminoma achieved complete response at the end of chemotherapy . - pubmed
Two patients who underwent resection of the residual tumour mass are surviving free of disease . - pubmed
Nine out of 9 patients with seminoma and 4/9 with non - seminoma are surviving disease - free at a median follow - up of 48 months ( range 16 153 months ) . - pubmed
Effect of sucralfate on aspirin induced mucosal injury and impaired haemostasis in humans . - pubmed
Twenty - four hour blood pressure profile of different doses of candesartan cilexetil in patients with mild to moderate hypertension . - pubmed
Visual assessment of human skin irritation : a sensitive and reproducible tool . - pubmed
Human volunteer studies of skin irritation have been carried out for decades , both for research and for safety evaluation purposes . - pubmed
However , it is possible to use the human eye , which is a very sensitive tool , to make detailed , accurate and reproducible descriptions of skin irritation reactions . - pubmed
CASE REPORT : An 86 - year - old woman , with a 16 - month history of an external auditory canal mass , presented with hemiparesis , facial paralysis , and obtundation . - pubmed
METHOD : The patient had a craniotomy for intracranial tumor resection with concurrent mastoidectomy for facial nerve decompression and obtundation and hemiparesis were resolved . - pubmed
Omeprazole or ranitidine plus metoclopramide for patients with severe erosive oesophagitis . - pubmed
In conclusion , superior efficacy at comparable cost is achieved by omeprazole compared with ranitidine / metoclopramide in the treatment of patients with severe erosive oesophagitis . - pubmed
About half ( 54 % ) of 106 patients with structural heart disease had surgically induced heart block . - pubmed
Patients with sick sinus syndrome had similar outcomes to those with AV block . - pubmed
The overall survival of young patients without structural heart disease who received a permanent pacemaker was comparable to an age- and sex - matched control population , while patients with structural heart disease performed significantly worse than the control population . - pubmed
This study examined 3 - dimensional ( 3D ) distribution of sectors with contrasting density in the equine third metacarpal ( McIII ) and third metatarsal ( MtIII ) bones with a view to explaining the aetiology of distal condylar fractures . - pubmed
[ Nitric oxide levels in cephalorhachidian++ fluid in patients with HIV infection ] . - pubmed
Three - dimensional spheroid cultures of human prostate cancer cell lines . - pubmed
BACKGROUND : Many of the available human prostate cancer ( PC ) cell lines have lost androgen sensitivity and no longer secrete prostate - specific proteins after serial culturing in cell monolayers . - pubmed
Detection of acute myocardial infarction by 99mTc - labeled D - glucaric acid imaging in patients with acute chest pain . - pubmed
To determine whether imaging with 99mTc - labeled D - glucaric acid ( GLA ) could provide this information , we imaged a group of patients presenting with symptoms suggestive of acute infarction . - pubmed
METHODS : Twenty - eight patients presenting to the emergency department with symptoms highly suggestive of acute infarction were injected with 99mTC - GLA and imaged about 3 h later . - pubmed
Fourteen patients with acute infarction injected within 9 h of onset of chest pain had positive scans , even in the presence of persistent occlusion . - pubmed
Nine patients with negative scans had acute infarction but were injected more than 9 h after onset of chest pain . - pubmed
The final diagnosis in the remaining 5 patients was unstable angina ( 3 injected & lt;9 h and 2 injected & gt;9 h after onset of chest pain ) . - pubmed
The eastern cottontail rabbit , Sylvilagus floridanus ( Allen ) , may play an important role in the epidemiology of Lyme disease in Missouri . - pubmed
Isolates of Borrelia burgdorferi Johnson , Schmid , Hyde , Steigerwalt & amp ; Brenner were made from ticks recovered from rabbits , making the cottontail rabbit a key species for further study of the epidemiology of Lyme borreliosis in Missouri . - pubmed
The following article analyses the available evidence of orlistat 's effectiveness in the treatment of obese patients . - pubmed
However , the results of the studies can not be easily generalised to obese patients in a primary care setting , due to limitations concerning the studies ' internal and external validity . - pubmed
CONCLUSIONS : Based on these studies orlistat is an efficient pharmacological treatment for obesity in patients adhering to a hypocaloric diet . - pubmed
Ralstonia solanacearum is a plant pathogen that is also a naturally transformable bacterium that can develop the competence state during infection of its host . - pubmed
Use of canaliculorhinostomy for repair of nasolacrimal duct obstruction in a horse . - pubmed
Alexithymic characteristics in children with refractory hematological diseases . - pubmed
Fluorescence polarization immunoassay : can it result in an overestimation of vancomycin in patients not suffering from renal failure ? - pubmed
It has been reported in scientific data that fluorescence polarization immunoassay ( FPIA ) results in overestimation of vancomycin in patients with renal failure . - pubmed
Increases in vancomycin levels have also been reported in patients not suffering from renal failure ( nonrenal failure patients ) who are receiving vancomycin therapy for approximately 10 days or more . - pubmed
Serum vancomycin peak and trough samples were obtained from 10 adult ( mean age + /- SD : 55.9 years + /- 17.5 ) nonrenal failure patients ( mean ClCr + /- SD : 76.2 mL / min + /- 29.20 ) receiving vancomycin therapy for at least 10 days . - pubmed
BSPM with 123 channels was performed in 45 patients with coronary artery disease ( CAD ) and 25 healthy controls during supine bicycle exercise testing . - pubmed
Of the 45 patients , 18 patients had anterior , 14 had posterior , and 13 had inferior ischemia documented by coronary angiography and thallium scintigraphy . - pubmed
Using a cut - off value of -10 microV , the ST depression separated the patients with CAD from controls with a sensitivity of 84 % and a specificity of 96 % . - pubmed
Expression profile of proteins involved in the xenotransplantability of non - small cell lung cancers into athymic nude mice . - pubmed
The aim of this study was to evaluate the expression profile of proteins involved in growing of human non - small cell lung cancer ( NSCLC ) in athymic nude mice . - pubmed
The expressions of 20 gene products in primary NSCLC of 170 patients were analyzed and the proteins were correlated with the transplantability of the carcinomas in nude mice . - pubmed
There was no relationship between xenotransplantability of human non - small cell lung cancer in nude mice and histology , stage or lymph node involvement . - pubmed
The resulting clusters were correlated with the take rate of the carcinomas in nude mice . - pubmed
We have previously documented that the dose of trimegestone is the main determinant of the pattern of bleeding in women treated with estradiol ( E(2 ) ) and sequential combined trimegestone administered in four doses . - pubmed
The objectives of this study were to test the effect of changing the dose of trimegestone and the duration of treatment on the pattern of bleeding in these women who then entered a 6 month extension phase where a single dose of trimegestone was given sequentially combined with E(2 ) . - pubmed
RESULTS : Women who had received trimegestone 0.25 mg / day during the first 6 months experienced no change in the bleeding pattern in the 6 month extension . - pubmed
Women who had been treated with 0.5 mg / day dose experienced earlier onset , and more prolonged bleeding ( P & lt ; 0.0001 ) following the change to 0.25 mg / day . - pubmed
Women who previously received trimegestone doses of 0.05 and 0.1 mg experienced a later onset of bleeding , which was lighter and of shorter duration ( P & lt ; 0.001 ) during the extension phase as compared with the first 6 months . - pubmed
Several clinical trials have determined that thalidomide is active in 25 - 35 % of patients with relapsed myeloma . - pubmed
The primary end - point of the present study was to investigate whether the alternating combination of vincristine - doxorubicin - dexamethasone ( VAD ) and melphalan - prednisone ( MP ) or vincristine - mitoxantrone - dexamethasone ( VND ) and MP could improve the clinical outcome of MM patients thus treated in comparison with those receiving MP alone . - pubmed
In both younger and elderly patients , severe granulocytopenia and related infections were significantly more frequent with VND / MP compared to the remaining arms of treatment ( p & lt ; 0.001 and p = 0.009 , respectively ) . - pubmed
INTERPRETATION AND CONCLUSIONS : Alternating VAD / MP and VND / MP failed to improve the clinical outcome for MM patients , at the cost of increased toxicity and morbidity . - pubmed
Ardisiphenols showed moderate scavenging activities toward 1,1 - diphenyl-2 - picrylhydrazyl ( DPPH ) radicals and showed cytotoxicity against the murine breast cancer cell line , FM3A. - pubmed
White - coat effect induced by therapist 's presence during speech therapy : study of post - stroke aphasic Japanese patients . - pubmed
OBJECTIVE : To delineate the clinical characteristics of post - stroke aphasic patients exhibiting the white - coat effect when a therapist is present during therapy session , 18 Japanese inpatients were studied . - pubmed
METHODS : Bronchial biopsy and sputum samples were collected from 120 patients confirmed to have lung cancer and 40 patients with benign pulmonary diseases . - pubmed
A case of necrotizing fasciitis in a dialysis patient is described . - pubmed
Two large phase III studies in patients with metastatic colon cancer established at least equivalent efficacy and improved tolerability for capecitabine compared to the Mayo Clinic bolus 5 - FU / folinic acid regimen . - pubmed
Phase II studies established remarkable activity in women with heavily pretreated metastatic breast cancer . - pubmed
Moreover the combination with a taxane yielded a unique survival benefit compared to the previous gold standard of taxane monotherapy in a phase III trial of women with anthracycline resistant breast cancer . - pubmed
The commonest side - effects are hand and foot syndrome , diarrhoea and stomatitis with serious adverse events occurring in a minority of patients . - pubmed
[ Morphological changes of cultured rabbit retinal cells after injury ] . - pubmed
PURPOSE : To investigate the morphological changes of cultured rabbit retinal cells after injury . - pubmed
We report an 8 - year - old girl with adhesion ileus complicated with jejunal perforation . - pubmed
The patient developed an anaphylactic reaction to parenteral nutrition . - pubmed
METHODS : From 1996 until 2002 , we analyzed 94 consecutive patients with postoperative colorectal anastomotic stenosis who were treated endoscopically . - pubmed
Dilatation was successful in 59 % of patients resected for cancer and 88 % resected for a benign condition . - pubmed
Complications developed in 17 patients ( benign restenosis , perforation , abscess ) ; they were significantly more frequent after initial cancer resection than after resection for a benign condition ( p & lt ; 0.05 ) . - pubmed
CONCLUSION : High success and low complication rates make endoscopic dilatation the treatment of choice to avoid high - risk reoperations in patients with benign anastomotic stricture . - pubmed
SUBJECTS AND METHODS : The authors analyze their experience with the course of pregnancy and delivery in a patient with MDS and refractory anaemia who was treated on account of the disease for several years before pregnancy in the Institute of Haematology and Blood Transfusion . - pubmed
Pregnancy was terminated in this patient on account of preeclampsia gravis per sectionem caesarean by delivery of a healthy foetus . - pubmed
Transfer of blood between " tritonized " and normal rats leads to a disappearance of the hypercholesteremia in the former and its appearance in the latter animals . - pubmed
Escherichia coli as a causative organism of infantile diarrhoea . - pubmed
Peripheral thyroxine metabolism in patients with psychiatric and neurological diseases . - pubmed
CASE SUMMARY : A 47 - year - old white man receiving combined mirtazapine and venlafaxine therapy for major depressive disorder developed agitation , confusion , severe shivering , diaphoresis , myoclonus , hyperreflexia , mydriasis , tachycardia , and fever on coadministration of tramadol for chronic pain . - pubmed
CONCLUSIONS : It is vital that clinicians are aware of the potential for SS when psychotropic and nonpsychotropic agents are coadministered to certain patients , such as those with both depression and chronic pain . - pubmed
Patients with an alcohol concentration<2 g / l had mostly soft tissue limb injuries ( 58 % ) , 2 - 2.5 mostly significant limb fractures ( 55 % ) , and & gt;2.5 mostly significant head injuries ( 90 % ) . - pubmed
Thyroid storm most often occurs in patients with known thyrotoxicosis . - pubmed
This report discusses a severe case of thyroid storm developing as a direct result of strangulation in a patient without a preexisting history of thyroid disease . - pubmed
Therefore identification of the molecular events underlying wound repair is essential to develop new effective treatments in support to patients and the wound care sector . - pubmed
METHODS : The present study consisted of 35 eyes ( 34 patients ) with full thickness corneal opacities and extensive corneal conjunctivalization after severe corneal burns . - pubmed
Inherited chondrodysplasia in Texel sheep . - pubmed
CASE HISTORY : A skeletal disease characterised by dwarfism , limb deformity and sometimes sudden death occurred over a period of 5 years in lambs born on a commercial sheep farm in Southland . - pubmed
CLINICAL FINDINGS : Affected lambs appeared normal at birth but showed evidence of dwarfism , wide - based stance and exercise intolerance as early as 1 week of age . - pubmed
Some severely - affected lambs died suddenly of respiratory embarrassment , probably due to tracheal collapse . - pubmed
Affected sheep that survived to breeding age eventually developed severe degenerative joint disease . - pubmed
DIAGNOSIS : Inherited chondrodysplasia of Texel sheep . - pubmed
CLINICAL RELEVANCE AND CONCLUSIONS : This chondrodysplasia differs from those previously described in sheep and is considered to be a newly - recognised , recessively - inherited genetic disease of the Texel breed . - pubmed
This disease of sheep may provide a suitable model for studying various forms of therapy for human chondrodysplasias . - pubmed
Primary cutaneous cryptococcosis in a patient with minimal change nephrotic syndrome . - pubmed
In the hippocampal formation of temporal lobe epilepsy patients , however , this stereotyped pattern of projection is often collapsed ; the mossy fibers branch out of the dentate hilus and abnormally innervate the dentate inner molecular layer , a phenomenon that is termed mossy fiber sprouting . - pubmed
Experimental studies have replicated this sprouting in animal models of temporal lobe epilepsy , including kindling and pharmacological treatment with convulsants . - pubmed
The influence of muscle type and dystrophin deficiency on murine expression profiles . - pubmed
MATERIAL AND METHODS : A retrospective chart review of 77 previously untreated patients with squamous cell carcinomas of the oral cavity with N0 neck from 1988 to 2001 was performed . - pubmed
The overall neck recurrence rate in patients with controlled primary disease was 2.4 % . - pubmed
No cervical recurrence occurred in 11 patients treated with SND alone . - pubmed
Non - invasive detection of latent cardiac conduction abnormalities in patients with pulmonary sarcoidosis . - pubmed
METHODS AND RESULTS : Ten patients with CS , 52 patients with pulmonary sarcoidosis ( PS ) but no obvious cardiac manifestations and 52 normal controls were studied . - pubmed
All participants underwent SAECG to detect LP . - pubmed
In 52 patients with PS , LP were detected in 25 patients ( 46.2 % , PS - LP(+ ) group ) , comparing only 3 ( 5.8 % ) of normal controls ( p<0.0001 ) . - pubmed
CONCLUSIONS : In the PS patients without obvious cardiac manifestations , LP were detected as high as 46.2 % , suggesting latent minute conduction abnormality . - pubmed
OBJECTIVES : To compare discontinuation rates of atypical antipsychotic agents in patients with schizophrenia . - pubmed
METHOD : Adult Maryland Medicaid patients with schizophrenia were categorized based on initial atypical antipsychotic drug received : aripiprazole ( n=446 ) ; olanzapine ( n=1705 ) ; quetiapine ( n=1467 ) ; risperidone ( n=1580 ) ; and ziprasidone ( n=700 ) . - pubmed
In this study we compared the effect of 21 % and 100 % reoxygenation on temporal changes in the plasma level of these factors in newborn piglets subjected to hypoxia . - pubmed
Newborn piglets were subjected to 2 h hypoxia followed by 1 h of reoxygenation with either 21 % or 100 % oxygen and observed for 4 days . - pubmed
Fanconi anemia ( FA ) patients have an increased risk for squamous cell carcinomas ( SCCs ) at sites of predilection for infection with high - risk human papillomavirus ( HPV ) types , including the oral cavity and the anogenital tract . - pubmed
We describe a 71 - year - old man who had received warfarin 7.5 mg / day for 5 years for atrial fibrillation , which had maintained his international normalized ratio ( INR ) within a narrow range of 2.5 - 3.2 . - pubmed
Potential further use of vaccines against Streptococcus pneumoniae and nontypeable Haemophilus influenzae means that M. - pubmed
These findings could indicate that marine strains of F. - pubmed
CsA neurotoxicity is the second major problem that seems underestimated especially in case of subtle manifestations in children . - pubmed
Electrostimulation to enhance salivary secretion has been used frequently as a research tool but only in limited extent as a clinical method to treat patients with xerostomia . - pubmed
MATERIALS AND METHODS : A Saliwell Crown was placed in the lower third molar area of an 81 - year - old female patient with complaints of dry and burning mouth . - pubmed
CONCLUSIONS : The saliva stimulation device Saliwell Crown , placed on an implant in an 81 - year - old patient with dry and burning mouth complaints , presented promising results when both the salivary secretion tests and the self - assessment questionnaires were examined and compared . - pubmed
3 - Nitropropionic acid ( 3 - NP ) is a plant - based mycotoxin that produces HD like symptoms in animals . - pubmed
RESULTS : Fourteen days of EGCG pretreatment ( 10 , 20 , and 40 mg / kg ) significantly attenuated behavioral alterations , oxidative damage , mitochondrial complex enzymes dysfunction , and striatal damage in 3 - NP - treated animals . - pubmed
The aim of the study was the assessment of therapeutic effectiveness of the phased application of Rifampicin and electropulse therapy in the treatment of patients with psoriasis . - pubmed
Under observation were 25 patients with vulgar psoriasis ( 13 women and 12 men aged from 18 to 65 years , with duration of illness from 1 month to 25 years ) . - pubmed
The effectiveness of treatment in patients receiving Rifampicin was the same regardless of the presence or absence of concomitant bacterial infection , which suggests that the positive therapeutic results of rifampicin is related not to its antibacterial , but to immunomodulatory effects . - pubmed
As a conclusion we can say that , the application of electropulse therapy and Rifampicin phase - treatment in patients with psoriasis reduces the period of the normalization of clinical indices for 7 days , as well as 2,5 times reduces the frequency of relapses in the year . - pubmed
Patients infected with human immunodeficiency virus ( HIV ) often progress to ESRD . - pubmed
Patients infected with HIV who also have ESRD are at risk for critical interactions between medication regimens to treat both of these conditions . - pubmed
Knowledge of antiretroviral regimens , drug interactions , and HIV resistance as well as the management of ESRD in the presence of HIV infection will improve the care of these unique patients . - pubmed
On the basis of initial leukocyte count and prognostic factors , patients enrolled in this study were divided into three risk groups ( early relapse , high leukocyte count and standard risk groups ) . - pubmed
On first year follow - up the patient had completely recovered with no neurological deficits . - pubmed
OBJECTIVE : To observe the effect of combined therapy with Xuezhikang Capsule ( XZK ) and Valsartan on left ventricular hypertrophy ( LVH ) and heart rate turbulence ( HRT ) in hypertensive patients . - pubmed
METHODS : Ninety primary hypertensive patients with LVH were randomly assigned to three groups . - pubmed
METHODS : A 37 - year - old right - handed woman became comatose after a motor vehicle accident with cerebral contusions and massive left cerebral edema . - pubmed
CONCLUSIONS : The label free QCM based biosensor was successfully developed to diagnose an abnormal human globin gene causing alpha - thalassemia 1 ( SEA deletion ) . - pubmed
In the present study we investigated this and the related process of inhibitory control at the youngest possible age through the study of infant siblings of children with an autism spectrum disorder ( Sibs - ASD ) . - pubmed
MATERIAL AND METHODS : Retrospective study of seventeen cases of children who were diagnosed with an arachnoid cyst during prenatal MRI between July 1994 and January 2007 and followed up for a mean 6 years and 6 months . - pubmed
RESULTS : Eight of the 17 patients included in this study underwent derivation surgery for the cyst . - pubmed
Two of the children in group 3 present with a supratentorial cyst , and 4 with a cyst of the posterior fossa . - pubmed
Whole - cell voltage - clamp recordings of lamina II neurons were performed in spinal cord slices from streptozotocin - induced diabetic rats . - pubmed
The amplitude of glutamatergic excitatory postsynaptic currents ( EPSCs ) evoked from the dorsal root and the frequency of spontaneous EPSCs ( sEPSCs ) were significantly higher in diabetic than vehicle - control rats . - pubmed
UK-14304 also inhibited the amplitude of evoked monosynaptic and polysynaptic EPSCs more in diabetic than control rats . - pubmed
In addition , intrathecal administration of UK-14304 increased the nociceptive threshold more in diabetic than vehicle - control rats . - pubmed
BACKGROUND AND AIMS : The Scottish Intercollegiate Guidelines Network ( SIGN ) has published guidelines for the management of children with head injuries . - pubmed
PATIENTS AND METHODS : This monocentric , observational , and retrospective survey was performed on 66 intensive care patients treated by antibiotics including vancomycin , alone or in combination , as a curative treatment for a severe infection with Gram - positive bacteria . - pubmed
Molecular profiling has allowed a more precise classification of human cancers . - pubmed
In addition , this approach can be used to determine the type of tumor represented by particular cell lines or transgenic animal models . - pubmed
Vigabatrin should be considered for rCPS if a patient has failed appropriate trials of other AEDs or is not a suitable candidate for other AEDs , is not an optimal surgical candidate , and continues to experience debilitating effects from seizures . - pubmed
Vigabatrin is indicated as monotherapy for pediatric patients with IS . - pubmed
Its efficacy in achieving improved seizure control should be apparent within 12 weeks in patients with rCPS and within 2 - 4 weeks after attaining appropriate dosage for patients with IS . - pubmed
Because 12 weeks is well less than the known time of onset of visual defects , the risk of developing pVFDs may be minimized by discontinuing vigabatrin early during the course of therapy for patients with inadequate response . - pubmed
Although some patients will be at risk of retinopathy , vigabatrin is an appropriate treatment option for patients who achieve substantial clinical benefit , especially given the severe consequences of rCPS and uncontrolled IS . - pubmed
OBJECTIVES : The purpose of this study was to assess the effect of remote ischemic precondition ( RIPC ) on the incidence of myocardial and renal injury in patients undergoing cardiovascular interventions as measured by biomarkers . - pubmed
Patients receiving RIPC had lower levels of markers of myocardial injury in the first few days after surgery ( standardized mean difference [ SMD ] , 0.54 ; 95 % confidence interval [ CI ] , -1.01 to -0.08 ; P=.01 ) with highly heterogeneous results ( I2 = 93 % ) . - pubmed
In patients undergoing abdominal aortic aneurysm repair , RIPC when compared to control also decreased renal injury ( SMD , 0.28 ; 95 % CI , -0.49 to -0.08 ; P=.007 ; I2 = 51 % ) . - pubmed
Genetic analysis of pathogen - specific clinical mastitis in Norwegian Red cows . - pubmed
The objective of this study was to estimate heritabilities and genetic correlations for pathogen - specific clinical mastitis ( CM ) in Norwegian Red cows . - pubmed
The 4 CM traits were defined as binary and scored as 1 if the cow had at least 1 case of the CM in question and 0 otherwise . - pubmed
aureus CM , 0.02 for Strep . - pubmed
The highest genetic correlation was found between unspecific CM and Strep . - pubmed
dysgalactiae CM , whereas the lowest was found for E. - pubmed
PROCEDURE : A prospective series of 425 patients ( 28 % of them adolescents ) with solid tumors was analyzed to investigate the correlation between symptom interval and age , and the different contributions to symptom interval in terms of the time from symptom onset to the first contact with a doctor ( patient delay ) , referral to the oncologist ( referral delay ) , and final diagnosis ( oncologist delay ) . - pubmed
The experience of our clinic between 2001 and 2011 covers 3500 cases of patients with bladder cancer . - pubmed
Complex mixtures of polycyclic aromatic hydrocarbons ( PAHs ) are present in air particulate matter ( PM ) and have been associated with many adverse human health effects including cancer and respiratory disease . - pubmed
It showed unsuspected N3 disease ( infraclavicular , supraclavicular , or internal mammary nodes ) in 40 patients and distant metastases in 53 . - pubmed
Inflammatory myofibroblastic tumor is an uncommon spindle cell tumor , occurring mainly in children and young adults . - pubmed
It is an extremely rare cardiac tumor especially patients under 1 year . - pubmed
Development and assessment of a complete - detoxication strategy for Fuzi ( lateral root of Aconitum carmichaeli ) and its application in rheumatoid arthritis therapy . - pubmed
AA model was established by incomplete Freund 's adjuvant injection in Wistar rats , and the animal 's physiological ( body weight , food intake , etc . ) - pubmed
Indigestible colonic substrates from brown beans may provide a preventive tool in relation to obesity and the metabolic syndrome . - pubmed
Twenty - five women with unilateral endometrioma underwent laparoscopic stripping of the endometrioma cyst capsule . - pubmed
PURPOSE : Radiation pneumonitis is the most severe dose - limiting complication in patients receiving thoracic radiation therapy . - pubmed
Tinea corporis occurred more frequently observed when T. - pubmed
Children with epilepsy often present with pervasive cognitive and behavioral comorbidities including working memory impairments , attention deficit hyperactivity disorder ( ADHD ) and autism spectrum disorder . - pubmed
Some of these children , particularly those with epilepsies classified as Landau - Kleffner Syndrome or continuous spike and wave during sleep , have infrequent seizure activity but frequent focal epileptiform activity . - pubmed
To this end , we have recently developed a rat model to test the role of frequent focal epileptiform activity in the prefrontal cortex . - pubmed
Using microinjections of a GABA(A ) antagonist ( bicuculline methiodine ) delivered multiple times per day from postnatal day ( p ) 21 to p25 , we showed that rat pups experiencing frequent , focal , recurrent epileptiform activity in the form of interictal spikes during neurodevelopment have significant long - term deficits in attention and sociability that persist into adulthood . - pubmed
Transcatheter aortic valve implantation ( TAVI ) is a therapeutic option for patients with severe aortic valve stenosis and high surgical risk . - pubmed
Data concerning combined TAVI and percutaneous coronary intervention ( PCI ) as an alternative treatment to surgery in high - risk patients with aortic valve stenosis and concomitant coronary artery disease ( CAD ) are limited , and no prior cases of an emergency procedure in cardiogenic shock have been described . - pubmed
Herein is presented the case of a 53 - year - old patient admitted in cardiogenic shock due to subacute myocardial infarction as well as high - grade aortic valve disease . - pubmed
We investigated Chl degradation during dehydration in both poikilochlorophyllous ( Xerophyta viscosa ) and homoiochlorophyllous ( Craterostigma pumilum ) species . - pubmed
Epidemiological evidence suggests that the consumption of fruits and vegetables may reduce the risk of both cancer and cardiovascular disease , and it has been hypothesized that this is due in part to the presence of antioxidant compounds in fruits and vegetables . - pubmed
CONCLUSIONS : Hypertension is common among HIV - positive individuals in rural Uganda . - pubmed
Similar chemopreventative strategies may be useful in humans who are at high risk of developing H.pylori - induced gastric adenocarcinoma . - pubmed
PATIENTS AND METHODS : From January 2011 to August 2014 , 21 patients underwent central quadrantectomy for carcinoma of the central region of the breast . - pubmed
Postoperative pathology revealed a tumor mean safety margin of 2.5 + -0.83 cm , with positive axillary lymph nodes in 15 ( 75.0 % ) patients . - pubmed
The study of genes associated with infertility in rodent models has expanded the field of translational genetics in identifying the underlying cause of human infertility problems . - pubmed
Many intriguing aspects of the molecular basis of infertility in humans remain poorly understood ; however , application of genetic knowledge in this field looks promising . - pubmed
The growing literature on the genetics of human infertility disorders deserves attention and a critical concise summary is required . - pubmed
CONCLUSIONS : Our findings suggest that the intestinal parasites infection was prevalent in captive Chinese alligators , and this condition requires our attention , whatever it is for controlling or preventing the intestinal parasitic disease from spreading to humans or conservation of this endangered species . - pubmed
The prognostic role of inflammation and hormones in patients with metastatic cancer with cachexia . - pubmed
Forty - six patients diagnosed with cancer cachexia and 34 healthy controls were included in the study . - pubmed
There were 36 male and 10 female patients in the cachexia group , and 24 male and 10 female patients in the control group . - pubmed
In vivo growth delay studies in the subcutaneous colon adenocarcinoma CT26.WT murine model were conducted at a photosensitizer dose equal to 0.5 and 0.2 MTD50 for TLD1411 and TLD1433 , respectively . - pubmed
The recombinant adenovirus was then delivered into the tumor - bearing rats and the results showed that such treatment significantly reduced the volumes of gliomas and improved the survival of the transplanted rats . - pubmed
Impact of Acute Kidney Injury on Early to Long - Term Outcomes in Patients Who Underwent Surgery for Type A Acute Aortic Dissection . - pubmed
We investigated the incidence and risk factors for AKI in patients with TA - AAD and its impact on their outcomes . - pubmed
Postoperative AKI was observed in 165 patients ( 44.0 % ) . - pubmed
METHODS : Patients with H&N cancer receiving RT as primary treatment were recruited . - pubmed
By mice tail amputation model and blood coagulation timing experiment , it is showed that this chitosan accelerated the tail hemostasis by 55 % and shortened the blood clotting time by 38 % . - pubmed
Although multiple sclerosis is a uniquely human disease , many pathological features can be induced in experimental autoimmune encephalomyelitis ( EAE ) models following induction of central nervous system - directed autoimmunity . - pubmed
However , the failure to translate many treatments from EAE into human benefit has led some to question the validity of the EAE model . - pubmed
Without EAE and other animal studies , clinical investigations will continue to be " look - see " exercises , which will most likely provide more misses than hits and will fail the people with MS that they aim to serve . - pubmed
METHODS : Patients included had primary cutaneous melanoma , Breslow thickness of 2.01 - 4.0 or & gt;4 mm with or without tumor ulceration ( T3a , T3b , T4a , T4b ) . - pubmed
Relationship between physical activity and function in elderly patients discharged after surgical treatment for gastrointestinal cancer . - pubmed
[ Subjects and Methods ] The study participants were 18 elderly patients who underwent surgical treatment for gastrointestinal cancer [ 10 males and 8 females , aged 71.4 + - 4.2 years ( mean + - SD ) ] . - pubmed
A total of 8 patients with high - grade NCL treated at our institution from 1992 to 2014 were identified . - pubmed
Primary tumor location was supraglottic in 7 patients and glottic in 1 patient . - pubmed
Locoregional recurrence followed by distant metastasis occurred in 6 patients . - pubmed
To our knowledge , this is the largest series of patients with high - grade NCL treated at a single institution . - pubmed
Relaxing effect of a new ruthenium complex nitric oxide donor on airway smooth muscle of an experimental model of asthma in rats . - pubmed
Protocol for PIT : a phase III trial of prophylactic irradiation of tracts in patients with malignant pleural mesothelioma following invasive chest wall intervention . - pubmed
These invasive procedures encourage tumour cell seeding at the intervention site and patients can develop tumour nodules within the chest wall . - pubmed
The T - plasty : a modified YV - plasty for highly recurrent bladder neck contracture after transurethral surgery for benign hyperplasia of the prostate : clinical outcome and patient satisfaction . - pubmed
OBJECTIVE : To describe a modified surgical technique for treatment of highly recurrent bladder neck contracture ( BNC ) after transurethral surgery for benign hyperplasia and to evaluate success rate and patient satisfaction of this novel technique . - pubmed
Patient reported functional outcomes were retrospectively analysed using a standardized questionnaire assessing recurrence of stenosis , incontinence , satisfaction and changes in quality of life ( QoL ) . - pubmed
The evaluation of myocardial function of patients in the early stage of acute ischemic stroke by two - dimensional speckle tracking echocardiography . - pubmed
METHODS : We included 29 patients with acute ischemic stroke , in whom NIHSS scores were calculated and stroke infarct volumes recorded . - pubmed
A novel biologically active acid stable liposomal formulation of docosahexaenoic acid in human breast cancer cell lines . - pubmed
Docosahexaenoic acid ( DHA ) , a component of fish oil , is known to suppress rat mammary carcinogenesis , reduce cell growth and induce apoptosis in human breast cancer cell lines . - pubmed
METHODS : We developed an acid stable liposome formulation of DHA by utilizing ether and phytanyl lipids similar in structure to those found in Archaea , known to endure high acidity and temperature ; we compared its biological activities with free DHA in human breast cancer cells . - pubmed
The Clinical Global Impressions Scale Modified for Substance Use ( CGI - SU ) in patients with bipolar disorder . - pubmed
Organ - sparing interventions also led to high patient satisfaction rates , but contain the risk of symptom recurrence . - pubmed
CT26 colon cancer mouse model was developed to study whether the combination of RT and GNPs reduced hypoxia - induced radioresistance . - pubmed
Interspecific cooperation : enhanced growth , attachment and strain - specific distribution in biofilms through Azospirillum brasilense - Pseudomonas protegens co - cultivation . - pubmed
Randomized controlled clinical trial assessing the effects of oral nutritional supplements in postoperative gastric cancer patients . - pubmed
BACKGROUND : Postoperative weight loss and malnutrition are major issues in gastric cancer patients . - pubmed
We investigated the effects of ONS administration on postoperative body weight loss in patients with gastric cancer who had undergone total gastrectomy or distal gastrectomy . - pubmed
The effectiveness of pre - discharge educational programs on adherence to medication regimens and relapse of schizophrenic patients . - pubmed
Epigenetic alterations underlie various human disorders , including cancer , and this has resulted in the development of drugs targeting epigenetic alterations . - pubmed
In the periodontopathogen Tannerella forsythia , several proposed virulence factors carry strain - specifically either a pseudaminic or a legionaminic acid derivative as terminal sugar on an otherwise structurally identical , protein - bound oligosaccharide . - pubmed
Image Gallery : Immunocompromised patient presenting with inguinal rash : a case of Scedosporium apiospermum . - pubmed
Suppressive effects of the expectorant drug ambroxol hydrochloride on quartz - induced lung inflammation in F344 rats . - pubmed
In the present study , we evaluated modulatory effects of ambroxol hydrochloride on quartz - induced lung inflammation in F344 rats . - pubmed
At 120 ppm , ambroxol hydrochloride significantly decreased individual lung inflammation scores for pulmonary edema and lymph follicle proliferation around the bronchiole , as well as the total inflammation score , in quartz - treated rats . - pubmed
This mini - review will discuss the clinical manifestations and management of children with ARPKD liver disease . - pubmed
Efficacy of Atypical Antipsychotics in the Management of Acute Agitation and Aggression in Hospitalized Patients with Schizophrenia or Bipolar Disorder : Results from a Systematic Review . - pubmed
Among available approaches , we discuss in detail recent evidence supporting the use of intramuscular ( IM ) antipsychotics and some recently approved oral atypical antipsychotics for the management of acute aggression and agitation in hospitalized patients with bipolar disorder or schizophrenia presenting with acute agitation or aggression , highlighting some differences between individual antipsychotic agents . - pubmed
Conclusions : A highly structured algorithm - guided treatment is associated with shorter times and fewer medication changes to achieve remission with depressed inpatients than treatment as usual or computerized medication choice guidance . - pubmed
Vitamin D - deficient mice have more invasive urinary tract infection . - pubmed
To determine if vitamin D had further protective mechanisms during urinary tract infections , we therefore used a mouse model . - pubmed
The patients ' clinical course is then typically complicated by ongoing inflammation , protein catabolism , and marked haemodynamic perturbation . - pubmed
[ Treatment outcome , survival and their risk factors among new tuberculosis patients co - infected with HIV during the Ebola outbreak in Conakry ] . - pubmed
BACKGROUND : Adjuvant chemotherapy is controversial in patients with locally advanced rectal cancer after preoperative chemoradiation . - pubmed
PATIENTS AND METHODS : VN and the NAR were applied to 158 consecutive patients with locally advanced rectal cancer treated with chemoradiation followed by surgery . - pubmed
The objective of this study was to evaluate the utility of serial radiographs in the clinical outcome of children with stable distal radius buckle fractures . - pubmed
Serial radiographs did not appear to change the excellent clinical outcome for children with distal radius buckle fractures . - pubmed
After VinV - TAVR procedure , 4 ( 2 % ) patients suffered from & gt;= moderate AR . - pubmed
Coronary obstruction was observed in 4 ( 2 % ) patients . - pubmed
Major bleeding and cerebrovascular complications ( according to VARC ) were reported in 3 ( 1 % ) and 4 ( 2 % ) patients at 30 days . - pubmed
Residual stenosis is a common finding which can be observed in 1/4 of patients undergoing VinV - TAVR . - pubmed
Enterocytozoon bieneusi genotypes in people with gastrointestinal disorders in Queensland and Western Australia . - pubmed
bieneusi in humans with gastrointestinal disorders in Queensland and Western Australia . - pubmed
bieneusi in Australia , to identify possible reservoirs of human infection , and to assist in the prevention and control of human microsporidiosis . - pubmed
Background : The treatment of patients with severe glenoid bone loss using reverse total shoulder arthroplasty ( RSA ) is challenging because of the difficulty in obtaining glenoid fixation . - pubmed
Proteomics of the wheat tan spot pathogen Pyrenophora tritici - repentis . - pubmed
OBJECTIVES : The fungus Pyrenophora tritici - repentis is a major pathogen of wheat worldwide , causing the leaf spotting disease tan spot . - pubmed
A survey of proteins secreted by the pathogen into culture filtrate is especially useful , as these are likely to come in direct contact with the wheat host and may play important roles in infection / pathogenicity . - pubmed
METHODS : We performed in vitro experiments in eight human HNSCC cell lines and a patient - derived HNSCC cell line as well as in vivo xenografts in a human HNSCC cell line . - pubmed
Understanding the molecular and cellular bases of improved outcomes of subsequent pregnancy may lead to the development of treatment modalities designed for women at high risk for pregnancy disorders originating at the maternal - fetal interface . - pubmed
During phase 2 , the patient performed without complaining of LBP , two repetitions of bench press exercise at a load intensity of 1.2 his body weight and attained 4 min of plank stabilisation . - pubmed
A 64 - year - old man had spasticity of digits 3 and 4 of the right hand for 22 years following a stroke . - pubmed
An equibiaxial strain value of 12 % was applied on rat PDLCs ( rPDLCs ) . - pubmed
One of the central mechanisms is molecular mimicry , which is also the most plausible mechanism in the case of ZIKV - induced autoimmune disorders . - pubmed
Thus , it is advised to evaluate and determine ZIKV exposure and infection in the management of potential GBS patients . - pubmed
Early Sociability and Social Memory Impairment in the A53 T Mouse Model of Parkinson ' s Disease Are Ameliorated by Chemogenetic Modulation of Orexin Neuron Activity . - pubmed
In this study , we investigated age - related reductions in sociability and social memory in the A53 T mouse model of PD . - pubmed
Moreover , DREADD - induced activation of orexin neurons restores social cognition in the A53 T mouse model of PD . - pubmed
In this study , we identified the A53 T mouse as a model of social cognitive impairment in PD . - pubmed
Relationship of CHA2DS2 - VASc score to left atrial volume and arterial stiffness in patients with atrial fibrillation . - pubmed
BACKGROUND : Transcutaneous carbon dioxide measurement ( TcCO2 ) is frequently used as a surrogate for arterial blood gas sampling in adults and children with critical illness . - pubmed
Studies included women 15 - 50 + years from 25 LMIC for indications including HIV prevention , contraception , abnormal bleeding , and menopause . - pubmed
Gender , age , AO / OTA fracture type , injury mechanism , inter - fragmentary gap , and follow - up time of patients were recorded . - pubmed
CONCLUSION : Patients with comminuted fractures of the inferior pole of the patella treated with a novel tension band experienced a longer operation time , but earlier partial - weight - bearing and fracture - healed time , better clinical outcomes at 12 - month follow - up , and less complications . - pubmed
Offspring of rats with cerebral hypoxia - ischemia manifest cognitive dysfunction in learning and memory abilities . - pubmed
Neonatal hypoxic - ischemic encephalopathy is a serious neurological disease , often resulting in long - term neurodevelopmental disorders among surviving children . - pubmed
Neonatal hypoxic - ischemic rat models were established by subjecting the rats to 8 % O2 - 92 % N2 for 2 hours . - pubmed
These results indicated that the offspring of hypoxic - ischemic encephalopathy model rats displayed cognitive impairments in learning and memory . - pubmed
Therefore , miR-92 could serve as a potential diagnostic and prognostic marker in glioma patients . - pubmed
Circulating inflammatory markers in cervical cancer patients and healthy controls . - pubmed
What is unclear still in the potential for modifications of host responses to human papillomaviruses ( HPV ) - a known causative agent of CC , that could be induced by cigarette smoking . - pubmed
The samples were the sera of 43 CC patients and 60 healthy ( NILM ) controls . - pubmed
Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy . - pubmed
Toward this goal , we aimed to identify biomarkers associated with BE and EAC in patients . - pubmed
However , significantly fewer infants in the fosphenytoin group had moderate - to - severe neurodevelopmental delay at the 18- and 24 - month assessments . - pubmed
Most studies about the efficacy and tolerability conducted so far were performed in adult cohorts , whereas few studies have been performed in children ; however , BRV was proven to be a useful ASM for paediatric focal epilepsies , with fewer studies and conflicting results among patients with generalized epilepsies and epileptic syndromes . - pubmed
Retention rates were high in the cohorts analysed , and no serious treatment - emergent adverse events were reported in the majority of patients , with somnolence , drowsiness , irritability , aggression and decreased appetite being the most frequently reported side effects . - pubmed
Although there are few original papers published on the subject so far , the analysis of the literature data demonstrated the efficacy and safety of BRV in paediatric patients , with more evidence for children aged 4 to 16 years with an onset of focal seizures . - pubmed
However , a positive response was also achieved in patients affected by encephalopathic epilepsies ( e.g Jeavons ' epilepsy , Dravet syndrome , Lennox Gastaut syndrome and juvenile myoclonic epilepsy ) , and ongoing studies are now testing BRV in order to widen its application to other forms of epilepsy and to test its effectivness when used in monotherapy . - pubmed
Recently resettled refugee populations may be at greater risk for exposure to severe acute respiratory syndrome coronavirus 2 ( SARS - CoV-2 ) , a virus that causes coronavirus 2019 ( COVID-19 ) , and face unique challenges in following recommendations to protect their health . - pubmed
Gene ontology analysis of public deposited gene array - based data and validation in our mouse model showed that the biological process " protein polyubiquitination " is enriched after CCl4 - induced liver fibrosis . - pubmed
Protection of guinea pigs against primary and recurrent genital herpes infections by immunization with live heterologous or homologous Herpes simplex virus : implications for a herpes virus vaccine . - pubmed
Guinea pigs , inoculated intravaginally with HSV type 2 develop a primary and spontaneously recurring genital herpes with clinical symptoms resembling genital herpes in humans . - pubmed
Prior infection with either subtype of HSV moderated considerably the acute disease induced by intravaginal HSV type 2 challenge . - pubmed
The degree of chimaerism of the coat , bone marrow and cornea in mouse chimaeras obtained by aggregation of an albino inbred embryo of A strain with an A X CBA - T6T6 hybrid was investigated . - pubmed
CPZ was tested here for its ability to inhibit the replication of Mycobacterium tuberculosis and Mycobacterium avium in cultured normal human macrophages , as determined by counts of viable bacteria at 0 , 4 , and 7 days after bacterial infection of the macrophages . - pubmed
Role and specificity of T - cell subsets in spontaneous recovery from Friend virus - induced leukemia in mice . - pubmed
Although rhabdomyosarcoma is predominantly a malignant disease of children , it is also seen in adults . - pubmed
Since adults account for only 15 % of rhabdomyosarcomas , the experience gathered for the treatment of the malignancy has been derived from treating children . - pubmed
reviewed the clinical histories of 500 patients presenting a malignant melanoma localized in the head and neck region and treated in their Hospital between 1967 and 1987 . - pubmed
An open continuation treatment trial was undertaken for schizophrenic and schizoaffective patients with postpsychotic depressions who had manifested favorable responses to initial treatment with adjunctive imipramine added to their fluphenazine decanoate and benztropine regimen . - pubmed
Of 27 patients enrolled , none had a psychotic or depressive relapse , and 23 completed the 6 - month study . - pubmed
The results therefore support continuation treatment with adjunctive antidepressant medication for those patients with postpsychotic depressions who initially respond favorably to this regimen . - pubmed
Methylene blue can be used to treat methemoglobinemia in cats without inducing Heinz body hemolytic anemia . - pubmed
Although prolonged treatment of cats for urologic syndromes with MB - containing antiseptics causes Heinz body ( HB ) hemolytic anemia , there is no evidence to suggest that single or repeated therapeutic doses of MB cause hemolytic anemia . - pubmed
We investigated the efficacy and safety of MB in reversing nitrite - induced MTHB in cats . - pubmed
Hemolytic anemia was not observed or demonstrated in any of the cats groups . - pubmed
Presentation of one case of gangrenous cystitis or vesical gangrene induced by the presence of a large vesical calculus in a patient with neurogenic bladder . - pubmed
Transesophageal echocardiography was used to study the effect of the balloon inflation on left ventricular function in 20 patients with critical aortic stenosis undergoing balloon valvuloplasty . - pubmed
Substance abuse in psychiatric patients admitted to the emergency room . - pubmed
Duodenogastric reflux was noted in 10 % of the patients as compared with 47 % before the operation . - pubmed
Fasting plasma glucagon was increased to 0.047 + /- 0.009 nmol / l ( P less than 0.05 ) in the non - diabetic dehydrated state ( normal 0.026 + /- 0.004 nmol / l ) , and a similar high level of plasma glucagon was observed in the dehydrated diabetic rat ( 0.052 + /- 0.020 nmol / l ) , especially after cortisol treatment . - pubmed
In the diabetic rat this ratio was not significantly different . - pubmed
Thus more catabolic hormonal changes were found in in vivo and in vitro studies in the hyperosmolar diabetic rat . - pubmed
Thirty - one patients suffering from acute frontal sinusitis were treated by trephination . - pubmed
Similar findings were obtained in a rat model of type I diabetes mellitus induced by streptozotocin in which glomerular hemodynamic factors appeared important to the development of progressive renal disease . - pubmed
Three hundred and fifteen patients with anterior uveitis associated with juvenile chronic arthritis ( JCA ) were studied in order to identify the various risk factors for uveitis . - pubmed
Girls were more susceptible to uveitis than boys by a ratio of 3:1 . - pubmed
Patients with pauciarticular onset JCA had the highest risk of uveitis and systemic onset patients the least risk . - pubmed
Sixty patients with palmoplantar pustulosis were treated in a double - blind trial with either acitretin ( etretin , Ro 10 - 1670 ) or with etretinate . - pubmed
It can be concluded that acitretin and etretinate do not significantly differ with regard to efficacy and overall safety in the treatment of patients with palmoplantar pustulosis . - pubmed
Variants of the R 3230 AC rat mammary adenocarcinoma were studied , including a subline with increased metastatic potential established by lung colony assay . - pubmed
Experiments carried out with sensitized guinea pigs showed a contribution of tracheobronchial C - fibers to the anaphylactic response . - pubmed
When 3H - proline was administered to spontaneously hypertensive ( SHR ) and Wistar - Kyoto ( WKY ) rats , its incorporation into non - collagen protein of the posterior cerebral artery or the mesenteric artery was greater in SHR than WKY . - pubmed
Administration of clonidine decreased the rate of incorporation of 3H - proline into the non - collagen protein of these arteries concomitantly with a reduction of blood pressure in each rat strain . - pubmed
Administration of 6 - OHDA slightly decreased the incorporation of the proline into the non - collagen protein of the SHR posterior cerebral artery , but failed to reduce blood pressure in each rat strain . - pubmed
Clodronate reduced serum calcium in 14 episodes and bone resorption in all patients . - pubmed
Clodronate may be a useful measure for controlling hypercalcaemia and osteolysis in patients with carcinoma . - pubmed
Results of genotoxicity testing of theophylline on bacteria and two lines of mammalian cells . - pubmed
Its potential mutagenicity was followed at the level of both bacteria and mammalian cells . - pubmed
Occlusion was caused by atherosclerosis in 43 patients , fibromuscular dysplasia in three , chronic dissection in two , abdominal aortic coarctation in one , and neurofibromatosis in one . - pubmed
Contralateral renal artery occlusive disease occurred in 22 patients . - pubmed
Extrarenal atherosclerosis occurred in 44 patients . - pubmed
Indication for renal revascularization was hypertension in 49 patients and preservation of renal function in one . - pubmed
At hospital dismissal , hypertension had improved in 45 of 46 patients . - pubmed
Thirty - four patients remained normotensive , five still had less hypertension , and seven became worse . - pubmed
These data demonstrate that revascularization of an occluded renal artery can be effective in controlling hypertension and that this effect is durable in the majority of patients . - pubmed
According to a retrospective questionnaire given to 389 students ( 191 girls and 198 boys ) , 50 ( 12.9 % ) had suffered from OSD . - pubmed
Cinematographic analysis of the initial motor syndrome of audiogenic epilepsy in the mouse ( Swiss albinos ) . - pubmed
Proceedings : The syndrome of acquired aphasia , EEG abnormalities with or without convulsive disorder in children . - pubmed
A controlled prospective trial was carried out in a group of 80 women undergoing gynaecological surgery and thought to be at risk of developing postoperative venous thrombosis . - pubmed
In the warfarin group , 12 out of 40 patients developed deep vein thrombosis , six of these episodes being classified as major and six as minor . - pubmed
In the dextran 70 group , 4 out of 40 patients developed deep vein thrombosis , all of them minor . - pubmed
Comparative observations on the production of fever by bacterial pyrogens and leucocytic pyrogen in goats and rabbits . - pubmed
[ Beginning of immunity in swine , inoculated with lapinized swine plague vaccine ] . - pubmed
The exposure of animal neutrophils to crystals implicated in joint inflammation induces superoxide and peroxide generation in a concentration and temperature dependent fashion . - pubmed
Urinary metabolites of catecholamines and indoleamines have been investigated in 16 patients with anorexia nervosa ( AN ) and 13 controls using a HPLC - method . - pubmed
In four patients long - term treatment including parenteral and enteral nutrition together with psychological methods resulted in an increase in the levels of these substances and this correlated with increased weight gain and urinary creatinine . - pubmed
The data indicated that the high rate of cortical bone resorption in experimental chicks was not increased above that observed in experimental chicks was not increased above that observed in control chicks . - pubmed
The insufficient mineral mass in vitamin D - deficient chicks resulted from the indirect inhibition of bone mineralization due to the low intestinal absorption of calcium rather than from a change in bone resorption . - pubmed
In vitamin D - treated chicks the apparent bone atrophy and net loss of ( 45 ) Ca from bone resulted from inhibiting bone matrix formation and mineralization instead of increasing bone resorption . - pubmed
The insect growth regulator diflubenzuron was found to be a potent inhibitor of melanosome synthesis and release in mouse melanoma cell cultures , and after three to five successive passages of melanoma cells in growth medium containing this compound , these cells were unable to produce monolayers in untreated medium and were incapable of inducing tumor formation in mice . - pubmed
67Ga scintigraphy was performed in 42 patients with pulmonary sarcoidosis and in 30 control subjects . - pubmed
The pattern of 67Ga accumulation clearly differed in patients who were radiographically defined as having only lymphadenopathy and in patients also having parenchymal involvement . - pubmed
The morphology of degenerative hip disease in male breeding turkeys . - pubmed
A form of degenerative joint disease in male breeding turkeys has been studied . - pubmed
Of 59 male breeding turkeys examined at approximately one year of age , antitrochanteric lesions were present in all but 5 of them . - pubmed
Acetone metabolism in mice : increased activity in mice heterozygous for obesity genes . - pubmed
Mice heterozygous for obesity - producing mutations , either obese ( ob/+ ) or diabetes ( db/+ ) , showed induction of the activity of this pathway to a significantly higher degree than did homozygous normal ( + /+ ) mice of the same strain . - pubmed
This more effective conversion of acetone to lactate exhibited by heterozygous mice could account for their prolonged survival on a starvation regimen compared to that of normal homozygotes . - pubmed
In cats the distal and proximal stumps of transected postganglionic bundles of the celiac ganglion were studied by the Falck -- Hillarp histofluorescence methods 72 hrs after transection . - pubmed
Surgical adjuvant therapy in colon carcinoma : a human tumor spheroid model for evaluating radiation sensitizing agents . - pubmed
HT-29 human colon tumor cells growing as spheroids have been evaluated as a model system for measuring the response of human colon tumor cell to antineoplastic agents . - pubmed
The multicellular HT-29 spheroids develop hypoxic centers reflecting the cellular conditions found in human cancer treatment , i.e. - pubmed
Allopurinol at a concentration of 100 microgram / ml was found to protect these human colonic carcinoma cells from the cytotoxic effects of 5 - FU under conditions resembling those found in vivo . - pubmed
Fine - needle aspiration samples from 54 consecutive patients suffering from prostatic benign lesions were analyzed for both cytological diagnosis and DNA cell content , by means of standard cytological criteria and flow cytometry , respectively . - pubmed
The purpose of this study was to isolate the effects of glucagon on the intestine by creating a rat model of segmental mesenteric ischemia that avoids the systemic shock associated with total superior mesenteric artery occlusion and reperfusion . - pubmed
Control animals ( n = 8) received normal saline solution ( 10 ml / kg / hr intravenously ) during ischemia and for 2 hours after declamping . - pubmed
RESULTS : Compared with nonischemic ileum , the ischemic segment in control animals showed severe mucosal injury with a reduction in mucosal thickness to 25 % , epithelial coverage to 23 % , and villar surface ratio to 33 % of that seen in nonischemic ileum ( p & lt ; 0.01 ) . - pubmed
[ The sensorimotor reactivity of rats with an initially high anxiety - phobia level ] . - pubmed
Sensorimotor response was measured by acoustic startle reflex in Wistar male rats with innate high and low levels of anxiety . - pubmed
The levels of anxiety were determined using a complex multiparameter method for evaluating anxiety - phobic states in rats by a ranged scale . - pubmed
Amplitude and prepulse inhibition of the acoustic startle response were increased , but latency of the startle reflex was decreased in rats with innate high level of anxiety as compared with those with innate low level . - pubmed
In rats with innate high level of anxiety injection of subconvulsive doses of pentylenetetrazol ( 10 and 15 mg / kg i.p . ) - pubmed
Facilitation of acoustic startle in rats with innate high level of anxiety is suggested to reflect either a deficit of inhibitory , or intensification of excitatory modulating influences on signal transmission in nerve circuit of acoustic startle . - pubmed
Studies of the sensorimotor response by acoustic startle in rats with innate high level of anxiety are believed to be useful for elucidating basic mechanisms of anxiety and phobia . - pubmed
Arterial puncture and hematoma were the commonest complications encountered in 8 and 4 per cent of the patients respectively . - pubmed
Pneumothorax occurred in two patients ( 1.6 % ) , while misplacement of catheter tip and thrombophlebitis was encountered in 0.8 per cent of all cannulations . - pubmed
Catheter related bacteremia ( recovery of the same organism from the catheter tip and peripheral blood cultures ) occurred in 31 of these 41 patients ( P & lt ; 0.01 ) . - pubmed
Of these patients 194 ( 48 % ) had calcification in the ligamentum arteriosum including 26 ( 6 % ) with calcification in the ligamentum arteriosum alone , 108 ( 27 % ) with atherosclerotic calcification , 11 ( 3 % ) with granulomatous calcification , and 49 ( 12 % ) with both . - pubmed
In the study population 169 patients ( 42 % ) had atherosclerotic calcification , 32 ( 8 % ) had granulomatous calcification , and 75 ( 19 % ) had both . - pubmed
The patterns of calcification for the 26 patients with calcification of the ligamentum arteriosum alone were curvilinear ( 7 patients , 27 % ) , punctate ( 17 patients , 65 % ) , and clumped ( 2 patients , 8 % ) . - pubmed
The pattern of ligamentum arteriosum calcification for the 108 patients with only atherosclerotic and ligamentum arteriosum calcification was curvilinear ( 28 patients , 26 % ) , punctate ( 32 patients , 30 % ) , and clumped ( 48 patients , 44 % ) . - pubmed
The patients without any calcifications and the patients with ligamentum arteriosum calcification formed one group ( based on their similarity in age , mean 47 years ) with a prevalence of ligamentum arteriosum calcification of 21 % . - pubmed
The patients with atherosclerotic and ligamentum arteriosum calcification formed a second group ( mean age 71 years ) with a prevalence of ligamentum arteriosum calcification of 65 % . - pubmed
Seventy - five percent of the dogs tested during the acute phase of disease and 100 % of the dogs tested during convalescence were seropositive for E. - pubmed
The geographic , clinical , serologic , and molecular evidence indicates that granulocytic ehrlichiosis in Minnesota and Wisconsin dogs is not caused by E. - pubmed
ewingii , but suggests that it is a zoonotic disease caused by an agent closely related to E. - pubmed
equi and that dogs likely contribute to the enzootic cycle and human infection . - pubmed
In this article , the natural history of congenital diaphragmatic hernia in humans is reviewed , and the development of antenatal management strategies is traced . - pubmed
OBJECTIVE : To investigate abnormalities of skeletal muscle metabolism in patients with congestive heart failure . - pubmed
During exercise , the degree of metabolic abnormality is related to the symptomatic status of the patient . - pubmed
Approximately 20 % of patients with ITP are refractory to corticosteroids and splenectomy . - pubmed
Recently , pulse high - dose dexamethasone was reported to be effective in the treatment of chronic ITP in adult patients . - pubmed
We treated 9 patients with severe chronic ITP with monthly high - dose dexamethasone . - pubmed
The standard antiplatelet and antithrombin agents used today in patients with acute coronary syndromes are aspirin and heparin . - pubmed
Low - molecular - weight heparins appear to be beneficial in patients with acute coronary syndromes . - pubmed
Recent trials with direct thrombin inhibitors in patients with acute coronary syndromes have demonstrated modest benefit , but also revealed their narrow therapeutic window and associated risk of bleeding . - pubmed
Further trials with novel antiplatelet and antithrombin agents in patients with acute coronary syndromes are ongoing . - pubmed
31P - NMR analysis of congestive heart failure in the SHHF / Mcc - facp rat heart . - pubmed
The SHHF / Mcc - fa(cp ) ( spontaneous hypertension and heart failure ) rat is a relatively new genetic model in which all individuals spontaneously develop congestive heart failure , most during the second year of life . - pubmed
4 K with dobutamine infusion , whereas hearts in end - stage failure were able to increase their RPP from baseline values of 27+/-4 K to only 37+/-7 K. The data indicate that a pronounced decline in PCr and total creatine signals the transition from compensatory hypertrophy to decompensation and failure in the SHF rat model of hypertensive cardiomyopathy . - pubmed
The purpose of this study was to compare the resting heart rates of 10 patients with panic disorder , 11 patients with social phobia , and 13 healthy controls during two consecutive visits to our laboratory . - pubmed
Glomerular filtration rate determination in diabetic patients using iohexol clearance -- comparison of single and multiple plasma sampling methods . - pubmed
The aim of this study was to determine whether single plasma sampling 4 h after injection of iohexol could accurately determine GFR in diabetic patients with mild to moderate renal failure , compared to multiple plasma sampling . - pubmed
Single plasma sampling 4 h after bolus injection of iohexol is a safe and accurate method of determining GFR and change in GFR in diabetic subjects with mild to moderate renal impairment . - pubmed
Fifty - nine patients had at least 4 LM , 62 had an associated EHL , and 187 had a surgical margin & lt ; 10 mm . - pubmed
Haemobartonellosis in squirrel monkeys ( Saimiri sciureus ): antagonism between Haemobartonella sp . - pubmed
A hemotropic parasite of the genus Haemo bartonella ( rickettsial parasite of the Family Anaplasmataceae ) is responsible for latent asymptomatic infection in colony - born Saimiri monkeys . - pubmed
In certain Saimiri monkeys , Haemobartonella parasitemia remains latent following removal of the spleen . - pubmed
Latent or patent haemobartonellosis might raise a problem when Saimiri monkeys are used as experimental hosts of Plasmodium falciparum asexual blood stages , as already noticed with " rodent malaria . " - pubmed
METHODS : Experimental TBI was induced in Sprague - Dawley rats by using a controlled cortical impact device at a velocity of 3 m / second , resulting in a 2 - mm deformation . - pubmed
Animals treated with Sm 0.04 % presented a high incidence of abortion and stillbirth . - pubmed
Mapping of two tumor suppressor genes in the pig . - pubmed
Kainic acid ( 12.5 mg / kg ) or saline was injected intraperitoneally into 12 - week - old male Fischer 344 rats and sacrificed by decapitation at 4 and 24 h after injection . - pubmed
METHODS : 50 patients with dilated cardiomyopathy were randomly assigned to double - blind treatment with 2 I.U. - pubmed
In order to overcome these limitations , new antifungal compounds are being developed , which may improve our therapeutic armamentarium for prevention and treatment of invasive mycoses in high - risk patients with neoplastic diseases . - pubmed
This limits the benefits of this therapy and excludes groups of patients such as young children , the elderly or hypoglycemia prone patients . - pubmed
The intensive therapy and self blood glucose monitoring ( SMBG ) necessary to limit hypoglycemia represent a heavy burden for the patients and their family . - pubmed
Axial computerized tomography simulation images of 25 patients with non - small - cell lung cancer were used in this study . - pubmed
The objective of the current study was to use the mouse phrenic nerve - hemidiaphragm preparation and botulinum serotype A to investigate 1 ) the relationship of substrate cleavage to toxin - induced paralysis , and 2 ) the relevance of substrate cleavage to the mechanism of toxin action . - pubmed
If animals failed to respond to an altered stimulus , we paired this stimulus with a weak electric shock during training . - pubmed
Kinetic analysis of cytokine gene expression in patients with GVHD after donor lymphocyte infusion . - pubmed
Patients who receive a donor lymphocyte infusion ( DLI ) for the treatment of relapsed leukemia after allogeneic BMT ( alloBMT ) often developed GVHD . - pubmed
These results suggest that Th1 dominates in the development of human clinical GVHD . - pubmed
A benign retroperitoneal schwannoma from a patient without prior exposure to radiotherapy or chemotherapy was analyzed by chromosome banding after short - term culture . - pubmed
Thus , our data clearly imply that if H3 G crosses the BBB with equivalent efficiency to M3 G , then the myoclonus , allodynia and seizures observed in some patients dosed chronically with large systemic doses of HMOR , are almost certainly due to the accumulation of sufficient H3 G in the central nervous system , to evoke behavioural excitation . - pubmed
We report the case of a patient with anti - GBM disease who initially presented with seronegative hemoptysis and normal urine . - pubmed
Brain activation patterns in response to increasing WM processing load ( auditory n - back : 0- , 1- , 2- , and 3 - back conditions ) were assessed with fMRI in 18 MTBI patients within 1 month of their injury and in 12 healthy controls . - pubmed
Brain activation patterns differed between MTBI patients and controls in response to increasing WM processing loads . - pubmed
MTBI patients showed disproportionately increased activation during the moderate processing load condition , but very little increase in activation associated with the highest processing load condition . - pubmed
MTBI patients showed a different pattern of allocation of processing resources associated with a high processing load condition compared to healthy controls , despite similar task performance . - pubmed
Based on the reports of UNSCEAR for the period from 1958 to 2001 the paper presents a retrospective analysis of the use of direct methods and the doubling dose method for quantitative determination of the genetic risk of human exposure expressed as different hereditary diseases . - pubmed
The level of human natural genetic variability per 1,000,000 newborns is estimated at 738,000 hereditary diseases including mendelian , chromosomal and multifactorial ones . - pubmed
The present case was diagnosed as teratoma in a feline unilateral cryptorchid testis . - pubmed
Outcome of lung transplantation in patients with mycetomas . - pubmed
Pulmonary mycetomas are found in patients with end - stage lung diseases , especially sarcoidosis . - pubmed
Patients were included in our study if mycetomas were present on the specimens . - pubmed
RESULTS : Mycetomas were present in 3.0 % of transplant recipients ( 9 of 303 patients ) . - pubmed
The underlying pulmonary diagnoses were sarcoidosis ( six patients ) , and emphysema , idiopathic pulmonary fibrosis , and pneumoconiosis ( one patient each ) . - pubmed
Two patients died at 17 months and 24 months posttransplant , respectively ; one patient received a second transplant 30 months later ; and two patients are alive and free from fungal infections 17 months and 18 months , respectively , after transplantation . - pubmed
Careful selection of patients and aggressive antifungal therapies before and after transplantation have led to improved outcomes in patients with mycetomas . - pubmed
All dogs developed diarrhea , which resolved in all CON dogs but persisted in all EXT DEN dogs . - pubmed
Despite greater weight loss and persistent diarrhea in EXT DEN dogs , at 12 weeks there were no differences in net absorptive fluxes between the EXT DEN and the CON group after extrinsic denervation . - pubmed
OBJECTIVE : To compare the perioperative outcome of patients & gt;or=13 years old undergoing surgery for congenital heart disease in a children 's hospital by a dedicated congenital heart surgery and anesthesia team with procedure - matched younger control patients . - pubmed
All major complications - cardiopulmonary resuscitation , neurologic injury , massive hemorrhage with sternotomy , femoral cannulation for emergent bypass , and severe episodes of hypotension on induction of anesthesia - occurred in older patients undergoing repeat sternotomy . - pubmed
METHODS : Using an autotransplantation pig kidney model , both early ( 40 min and 7 days ) and late ( 2 - 16 weeks ) changes in renal function and morphology were determined after different periods of cold ischemia in University of Wisconsin or Euro - Collins solutions . - pubmed
A 58 - year - old man was diagnosed as having type 3 gastric cancer ( poorly differentiated adenocarcinoma ) . - pubmed
In the field of gastric cancer treatment , especially for patients showing multiple resistance to anticancer drugs , an effective therapy is critically needed . - pubmed
A human neuroblastoma cell line ( IMR-32 ) , when differentiated , mimics large projections of the human cerebral cortex and under certain tissue culture conditions , forms intracellular fibrillary material , commonly observed in brains of patients affected with Alzheimer ' s disease . - pubmed
We have previously studied in vitro differentiation of murine neuroblastoma ( N1E-115 ) cells with respect to resting membrane potential development . - pubmed
Sixty cirrhotic patients and 21 age - matched control subjects without liver disease were included . - pubmed
Lymphomas were categorized into EBV - associated lymphoproliferative disease ( LPD ) and EBV - negative non - Hodgkin ' s lymphoma ( NHL ) , and the authors carried out separate analyses of these . - pubmed
Investigation of the relation of risk of EBV - negative NHL to degree of immunosuppression is needed . - pubmed
Since such an effect was seen in different animal models of Parkinson ' s disease ( PD ) , it seems that co - administration of SCH 58261 may allow for the lowering of the doses of L - DOPA in clinical practice , which indicates a potential therapeutic value of this compound in the treatment of PD . - pubmed
The Golgi complex and melanin elaboration of human melanomas in tissue culture . - pubmed
Selecting girls with precocious puberty for brain imaging : validation of European evidence - based diagnosis rule . - pubmed
STUDY DESIGN : A retrospective , multicenter , hospital - based , cohort study was performed , including all girls with CPP seen in 7 centers in 6 European countries during given periods . - pubmed
RESULTS : Girls with CPP ( n=443 ) , including 35 with OICL , were recruited . - pubmed
Nitric oxide synthesis is increased in the endometrial tissue of women with endometriosis . - pubmed
BACKGROUND : Previous studies have shown that peritoneal macrophages from women with endometriosis produce excess nitric oxide ( NO ) . - pubmed
RESULTS : Mean ( + /- SEM ) levels of NO were significantly increased in the endometrial tissues of women with endometriosis ( 13.2 + /- 7.8 versus 19.8 + /- 12.6 nmol / g tissue ; P = 0.016 ) . - pubmed
METHODS : We performed heterologous , left lung transplantation ( +4 degrees C ischemia ; 24 hours , Euro - Collins solution ) in 6 foxhounds ( untreated ) and in 6 animals that received calf lung surfactant extract ( Alveofact ) prior to explantation ( only donor lung ; 50 mg / kg body weight ) and immediately after onset of reperfusion ( both lungs , 200 mg / kg body weight ) . - pubmed
Studies on diabetic rats : the effect of diabetes and of diet upon the plasma and liver lipids of rats . - pubmed
We describe a patient whose testicular parenchyma was displaced by a cyst . - pubmed
Combination conformal radiotherapy and radioimmunoguided transperineal 103Pd implantation for patients with intermediate and unfavorable risk prostate adenocarcinoma . - pubmed
PURPOSE : To report outcomes for prostate cancer patients treated with external beam radiation therapy ( EBRT ) and permanent prostate brachytherapy utilizing radioimmunoguided targeting of biological tumor volumes ( BTVs ) . - pubmed
METHODS AND MATERIALS : Between February 1997 and October 2001 , 66 patients with intermediate- to high - risk prostate cancer underwent EBRT and ProstaScint - guided transperineal brachytherapy . - pubmed
Patients with intermediate- ( 1 RF ) and high - risk ( 2 - 3 RF ) prostate cancer exhibited 5 - year ASTRO - defined bDFS of 100 % and 81.9 % , respectively . - pubmed
Among all 26 patients available at postoperative follow - up ( mean 11.9 months ) , the mean loss of kyphosis correction was 2.0 degree . - pubmed
Excluded from analysis were 29 patients who required profound hypothermic circulatory arrest as a result of transverse arch involvement and 26 patients with aortic rupture , leaving a group of 300 patients for which outcomes were analyzed . - pubmed
The adjunct group of distal aortic perfusion and cerebrospinal fluid drainage used in 238 ( 79.3 % ) patients was compared with a group of 62 patients who underwent simple cross - clamp with or without the addition of a single adjunct . - pubmed
RESULTS : The incidence of neurologic deficit after all repairs was 2.3 % ( 7 of 300 patients ) . - pubmed
The incidence of neurologic deficit ( immediate and delayed ) in the adjunct group was 1.3 % ( 3 of 238 patients ) , and in the nonadjunct group was 6.5 % ( 4 of 62 patients ; p & lt ; 0.02 ) . - pubmed
All neurologic deficits occurred in patients with aneurysmal involvement of the entire descending thoracic aorta ( extent C ; p & lt ; 0.02 ) . - pubmed
METHODS : We evaluated 564 patients with rheumatoid arthritis ( RA ) and 155 controls using both techniques . - pubmed
We present here one such case of myelofibrosis where the patient was treated with radiotherapy to the spleen for symptomatic relief . - pubmed
Helicobacter pylori causes various gastro - duodenal diseases , including gastric cancer . - pubmed
In contrast , recently ill and chronically ill schizophrenia patients as well as patients at high risk for schizophrenia all failed to show this early ERP component while attending to color . - pubmed
Metabolic control and nocturnal enuresis in children with type 1 diabetes . - pubmed
This study examined the relationship between metabolic control and enuresis in youths with type 1 diabetes . - pubmed
Participants were 203 youths with type 1 diabetes at an outpatient pediatric diabetes clinic . - pubmed
The mean fasting blood glucose ( FBG ) level of children with enuresis ( FBG = 192 mg / dl ) was significantly higher than that of children without enuresis ( FBG = 160 mg / dl , p = .03 ) . - pubmed
Subacute stent thrombosis was detected in 2 patients with failure of FKBI in the classic crush group ( 4.3 % ) . - pubmed
CONCLUSIONS : Compared with classic crush , DK crush has the potential to improve the clinical outcome in patients with coronary bifurcation lesions . - pubmed
We assessed the outcome of 170 patients with AML in first complete remission , aged 1 - 47 years ( median 29 ) , who had undergone an allogeneic BMT before or after 1990 ( n=80 and n=90 , respectively ) ; all patients were prepared with cyclophosphamide and TBI ; the median follow - up for surviving patients was 13 years . - pubmed
Patients transplanted after 1990 were older , had a shorter interval diagnosis - BMT , had less FAB - M3 cases , received a higher dose of TBI , a higher marrow cell dose and combined ( cyclosporine+methotrexate ) GVHD prophylaxis . - pubmed
We investigated the effects of a continuous administration of high doses of selenium in septic shock patients . - pubmed
METHODS : A prospective , multicentre , placebo - controlled , randomized , double - blind study was performed with an intention - to - treat analysis in severe septic shock patients with documented infection . - pubmed
CONCLUSION : Continuous infusion of selenium as sodium selenite ( 4,000 microg on the first day , 1,000 microg / day on the nine following days ) had no obvious toxicity but did not improve the clinical outcome in septic shock patients . - pubmed
RECENT FINDINGS : Children with inflammatory bowel disease are at risk for more difficulties in psychosocial functioning than healthy children , particularly depression , anxiety and social difficulties . - pubmed
One pilot study suggests psychotherapy is effective for depressed adolescents with inflammatory bowel disease . - pubmed
The vascular delivery paradigm found successful in the mouse was carried to the non - human primate to test its potential translation to boys with DMD . - pubmed
In this prospective study , we estimated the prevalence of restless legs syndrome ( RLS ) in multiple sclerosis ( MS ) patients , and compared the extent of brain and cervical cord damage between patients with and without RLS using conventional and diffusion tensor magnetic resonance imaging ( MRI ) . - pubmed
Eighty - two consecutive MS patients were evaluated . - pubmed
Thirty subjects had RLS ; they showed a higher Expanded Disability Status Scale score than patients without . - pubmed
Cervical cord average FA was significantly reduced in MS patients with RLS compared to those without . - pubmed
BACKGROUND : Intussusception remains a common cause of bowel obstruction in young children and results in significant morbidity and mortality if not promptly treated . - pubmed
METHODS : Children treated for intussusception over a 15 - year period were reviewed after treatment at a tertiary children 's hospital . - pubmed
RESULTS : Two hundred forty - four children with intussusception were identified . - pubmed
One hundred forty children required surgical intervention for intussusception with 50 % requiring bowel resection . - pubmed
Interestingly , the suppressors had very different effects on crucifer - infecting Tobamovirus ( crTMV ) infections . - pubmed
's assertions that the Siberian " ice viruses " are most closely related either to avian influenza virus or to human influenza virus strains from Asia from the 1960s ( Zhang et al . - pubmed
Efficacy and safety of OCTANINE F in children with haemophilia B. - pubmed
The primary objective of this trial was to investigate the immunogenicity of OCTANINE F in children aged & lt;6 years with haemophilia B. - pubmed
Twenty - five children aged & lt;6 years with moderate or severe haemophilia B , including six who were previously untreated and 13 who had less than previous 50 exposure days were assigned to prophylactic or on - demand treatment with OCTANINE F over a 12- to 24 - month period . - pubmed
[ Anesthesia for a patient with stiff - person syndrome ] . - pubmed
The authors reported here a case of an axilally lymphadenectomy in a 46 - year - old woman with stiff - person syndrome . - pubmed
Quantifying hepatitis C transmission risk using a new weighted scoring system for the Blood - Borne Virus Transmission Risk Assessment Questionnaire ( BBV - TRAQ ): applications for community - based HCV surveillance , education and prevention . - pubmed
BACKGROUND : The hepatitis C virus ( HCV ) is a major cause of drug - related morbidity and mortality , with incidence data implicating a wide range of HCV transmission risk practices . - pubmed
rotata aqueous extract ( LRAE ) was given to mice at concentrations of 0.5 , 1.0 , 2.0 g / kg body weight and 0.75 , 1.5 , 3.0 g / kg to rats . - pubmed
A 74 - year - old man with hypertension presented with foamy urine and intermittent right upper quadrant abdominal pain . - pubmed
The medial longitudinal fasciculus ( MLF ) is a key brainstem pathway for ocular adduction and is commonly injured in patients with MS , typically resulting in internuclear ophthalmoparesis . - pubmed
Patients Six patients with chronic , unilateral , or bilateral internuclear ophthalmoparesis and 10 healthy control subjects . - pubmed
METHODS : A total of 213 elderly patients were divided into 4 groups according to the criteria defined by the American College of Chest Physicians/ Society of Critical Care Medicine ( ACCP / SCCM ) , namely the non - sepsis group ( group A ) , sepsis group ( group B ) , severe sepsis group ( group C ) and septic shock group ( group D ) . - pubmed
Strains of Escherichia coli , Zymomonas mobilis , and non - Saccharomyces yeasts were unable to surmount the 2 % butanol growth barrier . - pubmed
Several strains of Saccharomyces cerevisiae exhibit limited growth in 2 % butanol , while two strains of Lactobacillus were able to tolerate and grow in up to 3 % butanol . - pubmed
METHODS : A total of 1,286 children ( 6 - 12 yr ) were clinically examined for goitre from study areas of Imphal east district . - pubmed
PURPOSE : To assess the outcome of urologic evaluation in patients with voiding dysfunction due to multiple sclerosis ( MS ) and to determine the relationship between urological and neurological parameters of these patients . - pubmed
MATERIALS AND METHODS : We retrospectively reviewed the medical records of 249 consecutive patients ( 162 female and 87 male ) with MS who were referred to our clinic between 1991 and 2006 , with a median time of 4 years ( range 3 months to 26 years ) of MS onset . - pubmed
RESULTS : All patients except 13 had lower urinary tract symptoms and 70 % manifested mixed symptoms . - pubmed
Urodynamic evaluation of 75 patients ( 30.1 % ) revealed detrusor overactivity with or without detrusor - sphincter dyssynergia in 56 ( 75 % ) . - pubmed
CONCLUSIONS : The prevalence of mixed symptoms in patients with MS is higher than storage or voiding symptoms alone . - pubmed
PATIENTS AND METHODS : One hundred and ninety - two patients with complex / staghorn renal calculi who were treated with PCNL requiring multiple tracts were included in the study . - pubmed
Infections with influenza A viruses are still a major threat to humans and several animal species . - pubmed
The occurrence of highly pathogenic avian influenza viruses capable of infecting and killing humans highlights the urgency for a new and efficient strategy for the treatment of diseases caused by the virus . - pubmed
The administration of AL-1 by oral gavage to mice infected with avian influenza A / Chicken / Guangdong / 96 ( H9N2 ) , A / Duck / Guangdong / 99 ( H5N1 ) , and human influenza A / PR / 8 / 34 ( H1N1 ) viruses greatly reduced the death rate , prolonged life , inhibited lung consolidation , and reduced viral titers in the lung . - pubmed
The LD(50 ) of AL-1 was 1243 mg / kg / d. AL-1 was effective against avian influenza A ( H9N2 and H5N1 ) and human influenza A H1N1 viruses in vitro , with the 50 % effective concentrations ranging from 7.2 to 15.2 microM and the selective indexes ranging from 51 to 109 . - pubmed
Evaluation of the use of prognostic information for the care of individuals with venous leg ulcers or diabetic neuropathic foot ulcers . - pubmed
Chronic colitis ( CC ) was induced in BALB / c mice using dextran sodium sulfate . - pubmed
PROCEDURES : Groups 1 - 4 of nude mice bearing human breast carcinoma were injected with phosphate - buffered saline , TRA-8 , bevacizumab , and TRA-8 + bevacizumab on day 0 , respectively . - pubmed
OBJECTIVE : We describe the case of a young male patient with invasive ductal breast carcinoma . - pubmed
MATERIALS AND METHODS : Diffusion - weighted imaging data from 11 patients ( M : F = 7 : 4 , aged from 1 to 22 years , mean = 12.3 years ) who visited the epilepsy clinic and received a routine seizure protocol MRI exam were retrospectively analyzed . - pubmed
Rotavirus incidence and genotype distribution before and after national rotavirus vaccine introduction in Belgium . - pubmed
pneumoniae infection , suggesting that S. - pubmed
After detailed investigations , the final adjudicated diagnosis was acute coronary syndrome in 30 patients ( including acute myocardial infarction in 13 and unstable angina in 17 ) and non - acute coronary syndrome in 28 patients . - pubmed
Mechanical properties of single bovine trabeculae are unaffected by strain rate . - pubmed
Anxiety and depression are two of the most prevalent clinical manifestations of patients with CP / CPPS , and have adverse effects on the health of the subjects and prognosis of comorbidities . - pubmed
Of the 77 patients with CP / CPPS , 48 ( 62.3 % ) , 5 ( 6.5 % ) , and 1 ( 1.2 % ) had anxiety symptoms , depression symptoms , or both anxiety and depression symptoms , respectively . - pubmed
Ventricular and supraventricular arrhythmias and heart failure in a patient with left ventricular noncompaction and Brugada syndrome . - pubmed
Upon infection and development within human erythrocytes , P. - pubmed
A 34 - year - old Nigerian man presented with nephrotic syndrome . - pubmed
The rate of complete tumor blockade [ FES standardized uptake value ( SUV ) & lt;=1.5 ] following TAM ( 5/5 patients ) was greater than the blockade rate following FUL ( 4/11 ; 2 - sided mid P = 0.019 ) . - pubmed
Gender differences in UV - induced inflammation and immunosuppression in mice reveal male unresponsiveness to UVA radiation . - pubmed
Immunosuppression attributed mainly to the UVB ( 290 - 320 nm ) waveband is a prerequisite for skin cancer development in mice and humans . - pubmed
This could explain the known gender bias in skin cancer development in both mice and humans . - pubmed
Re : An inducible model of abacterial prostatitis induces antigen specific inflammatory and proliferative changes in the murine prostate . - pubmed
OBJECTIVE : To evaluate the prevalence of pulmonary embolism(PE ) in patients with chronic obstructive pulmonary disease ( COPD ) exacerbations of unknown origin and to explore the risk factors associated with PE . - pubmed
METHODS : A total of 208 consecutive patients with COPD were referred to this hospital for severe exacerbations of unknown origin . - pubmed
RESULTS : The frequency of PE was 33 % in this series of 208 consecutive patients with COPD referred for exacerbations of unknown origin . - pubmed
CONCLUSIONS : This study showed a 33 % prevalence of PE in patients with COPD who were hospitalized for severe exacerbations of unknown origin . - pubmed
abortus 2308 from organic hydroperoxide stress in in vitro assays , this protein is not required for the wild - type virulence of this strain in cultured murine macrophages or experimentally infected mice . - pubmed
Renal impairment is known to increase rivaroxaban - associated bleeding risk in patients . - pubmed
These results were obtained during Sisymbrium officinale seed imbibition in the absence of endosperm rupture . - pubmed
[ Clinical analysis of hepatitis B virus mutations related to adefovir dipivoxil among patients with chronic hepatitis B virus infection in eastern Zhejiang province ] . - pubmed
OBJECTIVE : To explore the clinical characteristics of hepatic B virus ( HBV ) mutations related to adefovir dipivoxil ( ADV ) among patients with chronic HBV infection in eastern Zhejiang province and provide some reference values on normative usage of antiviral drugs . - pubmed
METHODS : The data of chronic HBV - infected patients with HBV mutations related to ADV ( n = 88 ) and non - mutation ( n = 202 ) from June 2008 to August 2010 were analyzed retrospectively . - pubmed
CONTEXT : Nonspecific changes ( nonspecific chronic inflammation ) in patients with chronic diarrhea represent the commonest diagnosis in colorectal biopsy interpretation , but these changes are of little clinical significance . - pubmed
DESIGN : Detailed clinical features and histologic findings were analyzed in a cohort of 47 patients with chronic diarrhea , with near - normal histology and no clear - cut known etiologic agent . - pubmed
CONCLUSIONS : Lymphocytic follicles and aggregates colitis , previously regarded as of negligible diagnostic significance , allows the prediction of the behavior of chronic diarrhea in a subset of patients with nonspecific changes on colonic biopsy . - pubmed
Semiquantitative analysis of brain metabolism in patients with paraneoplastic neurologic syndromes . - pubmed
PURPOSE : The objective of this study was to evaluate brain metabolism with F - FDG - PET in patients with definite or possible paraneoplastic neurologic syndromes ( PNS ) using qualitative assessment and semiquantitative measurements with subsequent correlation with MRI . - pubmed
A prospective PET database of patients referred for PNS between 2001 and 2010 was queried retrospectively and identified 102 patients who met the diagnostic criteria for PNS , had PET brain imaging , and lacked clinical or MRI evidence of an alternative diagnosis . - pubmed
Both qualitative and semiquantitative analyses of brain glucose metabolism may be helpful in evaluating PNS , especially in patients with a normal MRI . - pubmed
Elevated T - wave alternans predicts nonsustained ventricular tachycardia in association with percutaneous coronary intervention in ST - segment elevation myocardial infarction ( STEMI ) patients . - pubmed
We examined whether T - wave alternans ( TWA ) level is correlated with nonsustained ventricular tachycardia ( NSVT ) incidence in association with PCI in patients with acute ST - segment elevation myocardial infarction ( STEMI ) . - pubmed
METHODS AND RESULTS : We analyzed continuous 24 - hour ambulatory electrocardiograms in 48 STEMI patients during and after successful primary PCI , achieving Thrombolysis in Myocardial Infarction ( TIMI ) grade 3 flow . - pubmed
Maximum TWA was elevated in patients with ( N = 22 ) compared to without ( N = 26 ) NSVT ( 75.1 + - 6.3 vs 49.9 + - 3.6 muV , P & lt ; 0.005 ) during the 22 - hour monitoring period . - pubmed
Here we injected brain extracts from humans who had died with various tauopathies into the hippocampus and cerebral cortex of ALZ17 mice . - pubmed
Similar inclusions also formed after intracerebral injection of brain homogenates from human tauopathies into nontransgenic mice . - pubmed
Subcutaneous specific immunotherapy was performed in 57 ( 70.3 % ) allergic patients . - pubmed
For the treatment of the developed rhinitis , we used intranasal glucocorticosteroids in all 47 ( 37.9 % ) patients with rhinitis medicamentosa . - pubmed
Only 5 ( 17.2 % ) patients with specific immunotherapy developed rhinitis medicamentosa . - pubmed
Specific immunotherapy is recommended for the prevention of rhinitis medicamentosa in patients suffering from allergic rhinitis , whereas intranasal glucocorticosteroids are the most appropriate for the treatment regardless initial cause of rhinitis development . - pubmed
Potentiation of cytotoxicity of paclitaxel in combination with Cl - IB - MECA in human C32 metastatic melanoma cells : A new possible therapeutic strategy for melanoma . - pubmed
Our aim was to investigate a possible combinatory therapeutic strategy using PXT and Cl - IB - MECA on human C32 melanoma cells and its underlying mechanisms . - pubmed
SUMMARY : Methods for the evaluation and management of patients with zygomatic fractures continue to evolve . - pubmed
It is the purpose of this Maintenance of Certification article to provide updated recommendations for preoperative assessment , surgical care , and postoperative management of patients with zygomatic fractures . - pubmed
In 10 chronically instrumented dogs , congestive heart failure ( HF ) was induced by high - frequency cardiac pacing . - pubmed
Patients on three or more antihypertensive drugs , with systolic BP values above & gt;=160 mmHg ( & gt;=150 mmHg for patients with type 2 diabetes ) are classified as having resistant hypertension . - pubmed
METHODS : One hundred neonates with NRDS were divided into NIPPV group ( n=50 ) and nasal continuous positive airway pressure ( NCPAP ) group ( n=50 ) . - pubmed
The results demonstrated the enhancement of the bone repair effects of ExCNFs by BMP in a rat femoral fracture model . - pubmed
PERFORM : a system for monitoring , assessment and management of patients with Parkinson ' s disease . - pubmed
In this paper , we describe the PERFORM system for the continuous remote monitoring and management of Parkinson ' s disease ( PD ) patients . - pubmed
This was done using skeletal muscle samples from men subjected to physiological conditions often investigated in applied physiology where the intervention has been suggested to impede normalization ( ageing , muscle atrophy , and different muscle fiber type composition ) . - pubmed
Pre - operative variables included the patients ' age , sex , the affected side , cause of injury , Tscherne classification of soft tissue injury , fracture pattern , and time from injury to surgery . - pubmed
BACKGROUND : Although radiotherapy is a key component of curative - intent treatment for locally advanced , unresectable non - small cell lung cancer ( NSCLC ) , it can be associated with substantial pulmonary toxicity in some patients . - pubmed
[ Oral ulcer as primary manifestation of HIV infection in an 80 - year - old man ] . - pubmed
Oral lesions such as candidiasis , Kaposi ' s sarcoma , hairy leukoplakia , herpes simplex infection , and ulcerative periodontitis are associated with HIV infection and may be the primary presentation in persons with undiagnosed HIV . - pubmed
We report a clinical case in which an 80 - year - old man presented with an oral ulcer with morphological signs of immuno - suppression . - pubmed
The patient was perceived to be at low risk of HIV infection and thus , diagnostic HIV testing was delayed until subsequent development of Kaposi ' s sarcoma on the skin . - pubmed
METHODS : Male SD rats were randomly divided into normal group and model group , which were administrated with high fat diet to establish nonalcoholic steatohepatitis model . - pubmed
At the end of the 4th or the 12th week , lipid droplets in the model rat liver cells were heavily dyed red and hepatic steatosis increased severely , with ballooning degeneration of liver cells . - pubmed
Superspectra created in this study enabled correct identification of 86 strains belonging to different subspecies of S. - pubmed
The aim of the current study was to examine whether there are differences in initial threat reactivity and the time course of threat responding during predictable and unpredictable threat - of - shock in 186 adults with : 1 ) current PD and no history of depression ( i.e. - pubmed
We measured preoperative psychological distress and substance use , and then measured pain and opioid use after surgery until patients reported the cessation of both opioid consumption and pain . - pubmed
Polysaccharide Agaricus blazei Murill ( pAbM ) has been found to have anti - cancer activity , but the underlying mechanism of this is poorly understood . - pubmed
In addition to , pAbM did not inhibit tumour growth in TLR2 (-/- ) mice . - pubmed
Reduced skeletal muscle quantity and quality in patients with diabetic polyneuropathy assessed by magnetic resonance imaging . - pubmed
METHODS : MRIs of the tibialis anterior ( TA ) muscle were recorded from 9 individuals ( 5 men ) with DPN ( ~65 years ) and 8 ( 4 men ) age- and gender - matched controls . - pubmed
Magnesium sulfate prevents maternal inflammation - induced impairment of learning ability and memory in rat offspring . - pubmed
The shuttle box is divided in half and the animal moves between compartments to avoid an electric shock in response to an auditory stimulus . - pubmed
37 % of patients had were found to have pathological tortuosity combined with haemodynamically significant ICA stenosis . - pubmed
It was demonstrated that surgical management of elderly patients with pathological tortuosity is an effective method of prevention of ischaemic stroke . - pubmed
The complications rate in patients presenting with combined atherosclerotic lesions of the ICA and its pathological tortuosity , should adequate surgical policy be employed , falls within the framework of the accepted standards and does not depend on the type of ICA lesion . - pubmed
Senescent peritoneal mesothelium induces a pro - angiogenic phenotype in ovarian cancer cells in vitro and in a mouse xenograft model in vivo . - pubmed
The same was the case for the vascularization , size and number of tumors that developed in the mouse peritoneum upon injection of ovarian cancer cells with senescent HPMCs . - pubmed
Signs of nausea - related behavior were observed in 25 % of the rats treated with buprenorphine . - pubmed
We describe a 16 - year - old boy with rhabdomyosarcoma , consistent with embryonal subtype , of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision . - pubmed
Stick injuries in dogs . - pubmed
Pulmonary Tuberculosis in Humanized Mice Infected with HIV-1 . - pubmed
Co - infection with HIV increases the morbidity and mortality associated with tuberculosis due to multiple factors including a poorly understood microbial synergy . - pubmed
We developed a novel small animal model of co - infection in the humanized mouse to investigate how HIV infection disrupts pulmonary containment of Mtb . - pubmed
Following dual infection , HIV - infected cells were localized to sites of Mtb - driven inflammation and mycobacterial replication in the lung . - pubmed
Consistent with disease in human subjects , we observed increased mycobacterial burden , loss of granuloma structure , and increased progression of TB disease , due to HIV co - infection . - pubmed
These results suggest that in the early stages of acute co - infection in the humanized mouse , infection with HIV exacerbates the pro - inflammatory response to pulmonary Mtb , leading to poorly formed granulomas , more severe lung pathology , and increased mycobacterial burden and dissemination . - pubmed
Despite efforts to fully understand the Bacillus anthracis toxin components , the gastrointestinal ( GI ) anthrax mechanisms have not been fully elucidated . - pubmed
In the present study , to identify the profile of the proteins potentially involved in GI anthrax , protein - protein interactions were investigated using human stomach T7 phage display ( T7PD ) cDNA libraries . - pubmed
BACKGROUND : Patient selection for endovascular revascularization treatment ( ERT ) in acute ischemic stroke depends on the expected benefit - risk ratio . - pubmed
METHODS : Consecutive stroke patients from a single stroke center with distal internal carotid artery- , proximal middle cerebral artery- or T - occlusions treated with ERT were retrospectively selected . - pubmed
Three patients ( 22 % ) had a lateral dural tear with an associated spinal meningeal diverticulum , and in 1 patient ( 7 % ) , a dorsal osteophyte was causal . - pubmed
METHODS : Thirty - four subjects with mild - to - moderate COPD were randomly allocated 2:1 to ICS or placebo treatment in a double - blinded clinical trial over 6 months . - pubmed
BACKGROUND : In the past 3 decades , a better understanding of gene mutations and their role in carcinogenesis has led to improvement in our ability to treat patients with metastatic disease . - pubmed
METHODS : DNA was collected from 165 randomly selected specimens of patients who underwent margin - negative resection of colorectal liver metastases with curative intent . - pubmed
BACKGROUND : Pleurostomophora richardsiae ( formerly Phialophora richardsiae ) is a dematiaceous fungus that is an uncommon cause of ocular infection . - pubmed
The patient was afebrile with leukocytosis . - pubmed
The patient died several weeks after presentation due to a massive intracranial hemorrhage . - pubmed
RESULTS : The histology of the breast tumour in the 58 patients was ductal type in 52 ( 90 % ) , lobular in 4 ( 7 % ) , and mucinous in 2 ( 3 % ) . - pubmed
The levels of TBRs were not significantly different between the patients groups with tumours of 2 cm or less and greater than 2 cm ( P=0.131 ) . - pubmed
Perioperative morbidity , oncological outcomes and predictors of pT3a upstaging for patients undergoing partial nephrectomy for cT1 tumors . - pubmed
Patients with pT3a had a higher estimated blood loss , transfusion rate , ischemia time and overall complications , though there were no differences in median e - GFR decline and major ( Grade III - V ) complications . - pubmed
The remaining 39 patients were not examined owing to volume intolerance , cow 's milk intolerance or allergy , inability to lie still , or parents refusing participation . - pubmed
GERD recurred in 7 ( 20 % ) patients . - pubmed
Preoperative T1/2 in the seven patients with recurrent GERD was median 45 [ 21 - 87 ] min compared to 44 [ 16 - 121 ] min in the 28 patients without recurrent GERD ( p=0.92 ) . - pubmed
Here , we review the literature that has led to our current understanding of B cell regulation of atherosclerosis , touching on the importance of subsets , local regulation , human translation , and therapeutic potential . - pubmed
High - dose chemotherapy followed by autologous stem cell transplantation ( ASCT ) is frequently performed in patients with hematologic malignancies . - pubmed
Music has been demonstrated to improve nausea and pain in patients undergoing chemotherapy , but little data are available regarding the effects of music therapy in the transplantation setting . - pubmed
In a prospective study , patients with lymphoma or multiple myeloma undergoing ASCT were randomized to receive either interactive music therapy with a board - certified music therapist or no music therapy . - pubmed
Secondary outcomes were narcotic pain medication use from day -1 to day +5 and impact of ASCT on patient mood as assessed by Profile of Mood States ( POMS ) on day +5 . - pubmed
Patients who received MT had slightly increased nausea by day +7 compared with the no music therapy patients . - pubmed
The music therapy and no music therapy patients had similar pain scores ; however , the patients who received music therapy used significantly less narcotic pain medication ( median , 24 mg versus 73 mg ; P = .038 ) . - pubmed
Music therapy may be a viable nonpharmacologic method of pain management for patients undergoing ASCT ; the music therapy patients required significantly fewer morphine equivalent doses compared with the no music therapy patients . - pubmed
Magnetic Resonance Diffusion data of 33 patients with BD , 19 with SCZ and 35 healthy controls were acquired . - pubmed
Respiratory syncytial virus in adults with severe acute respiratory illness in a high HIV prevalence setting . - pubmed
We studied the epidemiology of RSV - associated severe acute respiratory illness ( SARI ) hospitalizations in adults in South Africa from 2009 through 2013 . - pubmed
On multivariable analysis , HIV - infected individuals with RSV - associated SARI had greater odds of being in the age groups 18 - 44 and 45 - 64 years ( odd ratios ( OR ) 26.3 ; 95 % confidence interval ( CI ) 6.2 - 112.1 and OR 11.4 ; 95 % CI 2.6 - 50.0 ) compared with those & gt;=65 years and being female ( OR 2.7 ; 95 % CI 1.4 - 5.4 ) . - pubmed
The relative risk of hospitalization with RSV - associated SARI was 12 - 18 times higher in HIV infected individual compared to that of HIV - uninfected . - pubmed
CONCLUSION : The incidence of RSV - associated SARI was higher in HIV - infected individuals and those aged 65 years and older . - pubmed
Further studies are warranted to describe the disease association of RSV detected in adults with SARI . - pubmed
Nasopharyngeal and oropharyngeal swabs were collected from hospitalized patients meeting SARI case definitions and were analyzed for infection with influenza , respiratory syncytial virus ( RSV ) , adenovirus ( AdV ) , human metapneumovirus ( hMPV ) and human parainfluenza virus types 1 - 3 ( hPIV1 - 3 ) . - pubmed
Participants with hMPV infections and participants less than five years of age were significantly less likely than participants not infected with hMPV and those older than five years of age , respectively , to experience a severe outcome , while participants with a pre - existing chronic disease were at increased risk of a severe outcome , compared to those with no reported pre - existing chronic disease . - pubmed
To evaluate their potential anticancer effects on human carcinoma cells , anti - proliferation , DNA binding and cleavage , and apoptosis elicitation were examined . - pubmed
METHODS : Two hundred and thirty - five patients who underwent catheter ablation for paroxysmal AF ( 119 in irrigated - tip , 51 in contact - force sensing - guided , and 65 patients in second - generation cryoballoon ablation ) were included . - pubmed
Of the total population , 45 patients had recurrence . - pubmed
The aim of the study was to prospectively evaluate the prevalence and progression of HP in patients after TBI and SAH in Icelandic population . - pubmed
METHODS AND PROCEDURES : A total of 27 patients were included , 15 patients with TBI and 12 patients with SAH . - pubmed
RESULTS : At three months , 16.7 % ( 2/12 ) of the patients had HP after TBI and 33.3 % ( 4/12 ) after SAH . - pubmed
At 12 months , 21.4 % ( 3/14 ) of patients had HP after TBI and 9.1 % ( 1/11 ) after SAH . - pubmed
CONCLUSIONS : There is a considerable risk of HP after TBI and reason to study pituitary function further in patients with SAH . - pubmed
However , single time - point measurements appear to furnish insufficient information for detecting and predicting AKI in intensive care unit patients who are frequently affected by multiple and transient / persistent renal insults . - pubmed
RESULTS : Among the enrolled 272 patients , 33 were determined to show newly developed AKI after ICU admission , 58 showed worsening of AKI , 57 recovered from AKI , and 38 died in the hospital . - pubmed
We performed miRNA in situ hybridization , RNA - sequencing , and immunohistochemical analyses of tumor tissues from 51 untreated patients with EAC in the Netherlands . - pubmed
Clinical and survival data were collected for patients , and EAC subtypes were determined . - pubmed
Resident brain neural precursor cells develop age - dependent loss of therapeutic functions in Alzheimer 's mice . - pubmed
To evaluate brain NPC function in relation to disease pathology , we first characterized the pathological properties of 5xFAD transgenic mouse model of Alzheimer ' s disease at different ages . - pubmed
We found that age 7 months is a critical time point of heavy amyloid deposition and gliosis but before neurodegeneration and a normal basal rate of NPC turnover in the subventricular zone ( SVZ ) of 5xFAD mice as compared to wild - type mice . - pubmed
Importantly , these functions were fully preserved in 2 - month - old 5xFAD mice , a time point before Alzheimer ' s disease - specific pathological changes . - pubmed
The dysfunctional properties and downregulation of gene expression were reversible in NPCs derived from 7 - month - old 5xFAD mice following in vitro expansion and were reproduced in wild - type NPC by addition of amyloid beta peptide . - pubmed
In 218 consecutive symptomatic patients undergoing who underwent ablation for AF ( 143 paroxysmal AF ; 78 persistent AF ) , the EATV index ( EATVI : EATV / body surface area , mL / m2 ) was measured using 320 - row multidetector computed tomography . - pubmed
METHODS : Three - dimensional multiple b - value 3 He and 129 Xe diffusion - weighted MRI was acquired with compressed sensing at 1.5 T from 51 and 31 subjects , respectively , including healthy volunteers , ex - smokers , idiopathic pulmonary fibrosis , and chronic obstructive pulmonary disease patients . - pubmed
BACKGROUND : Anterior cruciate ligament ( ACL ) rupture is a serious injury in patients who are typically young and athletically active , with potential long - term complica- tions including functional limitation , posttraumatic osteoarthritis of the knee , and impaired quality of life . - pubmed
BACKGROUND : Besides the numerous biologic and pharmacologic functions in the human body that act as potent antioxidants , flavonoids ( flavones , flavanones , flavonols , flavanols and isoflavones ) are noted as cancer preventive or therapeutic agents . - pubmed
Dyslexic children are sluggish in disengaging spatial attention . - pubmed
The present study examined the time course of attentional orienting in dyslexic and typically developing children , by parametrically manipulating the cue - target onset asynchronies in a spatial cueing task . - pubmed
Experiment 1 revealed an early facilitation effect in dyslexic children , suggesting that they have no issue in engaging attention to salient spatial locations . - pubmed
When a second cue was presented to encourage attentional disengagement in Experiment 2 , reliable IOR effects were observed in the same group of dyslexic children , and importantly , the onset time of IOR was comparable with that in healthy controls . - pubmed
These results clearly show a selective impairment of attentional disengagement in dyslexic children and provide a solid empirical basis for intervention programmes focusing on attentional shifting . - pubmed
The in vivo anti - melanoma effects of HANPs were studied in the tumor model of nude mice . - pubmed
This study was designed to explore the currently understudied alternative mechanisms by which compound alpha - ketoacid tablets ( KA ) influenced ischemia - reperfusion ( IR ) induced murine renal injury , and to probe the current status of KA administration on staving CKD progression in Chinese CKD patients at different stages . - pubmed
METHODS : In animal experiment , IR surgery was performed to mimic progressive chronic kidney injury , while KA was administrated orally . - pubmed
In clinical research , after adjusting basic demographic factors , patients at stages 4 and 5 in KA group presented a much delayed and slower incidence of eGFR decrease compared to those in No - KA group ( hazard ratio ( HR ) = 0.115 , 95 % confidence interval ( CI ) 0.021 - 0.639 , p = 0.0134 ) , demonstrating a positive effect of KA on staving CKD progression . - pubmed
BACKGROUND : Documentation of disease activity in patients affected by Crohn ' s disease ( CD ) is mandatory in order to manage patients properly . - pubmed
CONCLUSION : LP on contrast - enhanced MRI is a specific finding to rule out active inflammation in patients with CD . - pubmed
We analyzed 225 fixed HCC tissues ( from 2 cohorts ) from patients in China by immunohistochemistry and obtained survival data . - pubmed
Human umbilical cord vein endothelial cells were exposed to sera from healthy donors ( n = 20 ) and patients with end - stage renal disease on haemodialysis ( n = 20 ) . - pubmed
Dilatation of Retinal Arterioles Induced by Topical Dorzolamide for One Week Is Impaired in Patients with Type 1 Diabetes and Mild Retinopathy . - pubmed
However , the effect of sustained treatment with CAI on retinal arterioles in normal persons and in patients with diabetic retinopathy is unknown . - pubmed
RESULTS : Treatment with dorzolamide for 1 week significantly increased the diameter of retinal arterioles in normal persons , and breathing in of a hypercapnic gas mixture reduced this response . - pubmed
The pathological vasodilatation and reduced retinal autoregulation in patients with diabetic retinopathy were unaffected by dorzolamide and hypercapnia . - pubmed
Releasing Wolbachia - infected Aedes aegypti to prevent the spread of dengue virus : A mathematical study . - pubmed
Wolbachia is a bacterium that is present in 60 % of insects but it is not generally found in Aedes aegypti , the primary vector responsible for the transmission of dengue virus , Zika virus , and other human diseases caused by RNA viruses . - pubmed
For AS patients , NSAID monotherapy increased the probability of hematuria 2.4 - fold and the probability of mixed manifestations of renal involvement 3.0 - fold . - pubmed
CONCLUSION : NSAID or csDMARD monotherapy may significantly increase renal involvement in Chinese AS patients . - pubmed
Methacholine challenge has proved to be a highly sensitive test to diagnose asthma in patients with chronic respiratory symptoms and preserved baseline lung function ( FEV1 > 70 % pred . ) - pubmed
We conducted a retrospective study on 270 patients recruited from the University Asthma Clinic of Liege . - pubmed
Controlling some metabolic variables will decrease the prevalence of these disorders and improves clinical remedy and quality of life in patients with type 2 diabetes . - pubmed
METHODS : Women > = 50 years of age with low - risk invasive breast carcinoma ( pT1 - 2 pN0 ) were randomly assigned to 50 Gy/25 fr ( 5 weeks ) or 30 or 28.5 Gy in 5 fr of 6.0 or 5.7 Gy ( 1 week ) . - pubmed
This study assessed the temporal pattern of neuronal loss in subacute ischemic stroke patients using 1H magnetic resonance spectroscopy , in parallel with functional recovery at 2 , 6 and 12 weeks after stroke . - pubmed
HPV - positive HNSCC cell lines show strongly enhanced radiosensitivity after photon but not after carbon ion irradiation . - pubmed
METHODS AND RESULTS : Prescription data for 450 518 patients with AF from 3352 General Practices in England , was obtained from the GRASP - AF registry , 2009 - 2018 . - pubmed
We apply this strategy to an ex vivo bovine model of discectomy and demonstrate that PEGDA molecular weight tunes hydrogel mechanical properties and affects herniation risk , where IVDs repaired with low - modulus hydrogels composed of 20kDa PEGDA failed at levels at or exceeding discectomy , the clinical standard of care . - pubmed
METHODS : This retrospective study included 43 patients diagnosed with BP . - pubmed
CONCLUSION : Although entrapment of FN in the labyrinthine segment in BP was known , this study showed that the cisternal FN , which could be evaluated more conveniently , enlarged in the paralytic side compared to the normal side , and revealed the necessity of performing the comparison among the MRI studies on BP patients by using a standardized measurement method . - pubmed
The emergence outbreak caused by a novel severe acute respiratory syndrome coronavirus 2 ( SARS - CoV-2 ) has received significant attention on the global risks . - pubmed
Neurosurgical consultation should be considered in pediatric patients with cerebellitis . - pubmed
Human intact tibiae were tested using the static bending method to learn about the relationship between the fracture surface and the failure mode . - pubmed
Zinc metabolism and dibutyl phthalate - induced testicular atrophy in the rat . - pubmed
Clinical features and results of nerve conduction and electromyographic investigations were studied in 13 consecutive patients with idiopathic ischemic necrosis of the femoral head . - pubmed
Of these patients , one was a diabetic , one had received steroids and six gave a history of high alcohol intake . - pubmed
Skeletal muscles of newborn albino mice experimentally infected with the virus showed degeneration , atrophy , necrosis , and inflammatory changes of muscle fibers . - pubmed
Antibody prevalence in humans and animals ranged from 10.3 % by neutralization tests of samples from healthy people in 1979 to 26.4 % by CF tests of samples from people with febrile illnesses in 1982 . - pubmed
The high prevalence of antibody in pigs , horses , and goats ( 17.6 % to 37.5 % ) indicated that infection with Getah or a closely related virus is relatively common in domestic animals . - pubmed
Clinical signs were confined to the lower limbs in 3 patients ; the remaining patient presented only paraesthesiae in 4 limbs . - pubmed
Hemodynamic effects of ibopamine on the pulmonary circulation and right ventricular performance in patients with chronic obstructive pulmonary disease . - pubmed
We have studied the effects of ibopamine , an oral dopamine derivative , on pulmonary hemodynamics and blood gas values when given as a single oral dose ( 100 mg ) to patients with severe hypoxic chronic obstructive pulmonary disease . - pubmed
These results do not indicate a role for ibopamine in the treatment of patients with hypoxic chronic obstructive pulmonary disease and pulmonary hypertension , but , in addition , do not indicate any major deleterious effects of ibopamine on pulmonary hemodynamics or blood gas values in such patients . - pubmed
[ Sputum penetration of levofloxacin and its clinical efficacy in patients with chronic lower respiratory tract infections ] . - pubmed
The clinical efficacy and the safety of LVFX were also evaluated in a total of 13 patients with respiratory tract infections associated with bronchiectasis , diffuse panbronchiolitis , etc . - pubmed
All the 3 strains of Haemophilus influenzae were eradicated . - pubmed
Of the 3 strains of Pseudomonas aeruginosa , eradication , decrease , and unchange was observed for 1 strain each . - pubmed
One strain of Streptococcus pneumoniae remained unchanged . - pubmed
Charts of 90 patients consecutively operated during 6 years for acute perforated ulcer were analysed . - pubmed
[ Spontaneous rupture of the abdominal wall in cirrhotic patients with ascites ] . - pubmed
Micromolar concentrations of diethyldithiocarbamic acid ( DDC ) kill fungi , bacteria and malaria . - pubmed
coli spheroplasts , suggesting a possible common mechanism of hemolytic and microbicidal action ; ( 2 ) higher ratios of drug : metal ( greater than 4:1 ) diminished hemolytic and , as observed earlier , microbicidal effects ; ( 3 ) cobalt , known to suppress the microbicidal effects of DDC : Cu , also prevented red cell lysis ; ( 4 ) despite the necessary involvement of copper in DDC - mediated hemolysis , there was no evidence of oxidative damage to erythrocytes , and both lysis of erythrocytes and killing of E. - pubmed
In contrast to adult mice , young A / J mice , developed an acute hepatitis following infection with Mouse Hepatitis virus type 3 . - pubmed
Studies of chemically induced cell injury and death , which have used as model systems freshly isolated rat hepatocytes and hepatocytes in culture , are discussed . - pubmed
Homogeneous distribution and pressure dependent reduction of coronary blood flow in right ventricular free wall during coronary hypoperfusion in anaesthetised open chest dogs . - pubmed
Chronic hypervitaminosis A in adults is a clinical syndrome that can develop over varying periods of time depending on the average daily intake of vitamin A. - pubmed
Hepatic cirrhosis developed as a manifestation of vitamin A toxicity in one of the patients ; this appears to be the first reported case of chronic hypervitaminosis A in an adult induced by the long - term frequent ingestion of beef liver . - pubmed
Ten patients have been studied using the Doppler flowmeter and phlebography to compare varicoceles and varicose veins in the legs and to decide whether or not the same principles apply in their surgical treatment . - pubmed
Gonadoblastoma arising from the streak gonad was noted in five of the six patients . " - pubmed
We recommend evaluation of the gonads in prepubertal girls with end - stage renal disease at risk for this syndrome . - pubmed
Escherichia coli strain N100 has been mutagenized by transposon mutagenesis and mutants with a cell surface leaky phenotype have been isolated . - pubmed
Partial splenic embolization in patients with thalassemia major . - pubmed
The sample consisted of lateral roentgenographic cephalograms from 41 children who had been treated with functional appliances for anterior crossbites and from their respective parents . - pubmed
The radiosensitizing and toxic effects of RSU-1069 on hypoxic cells in a murine tumor . - pubmed
Our studies have been carried out using the SCCVII squamous carcinoma implanted subcutaneously in C3H mice , using a technique we recently developed which facilitates isolation of tumor cell subpopulations from known locations relative to the tumor blood supply . - pubmed
The results obtained to date clearly demonstrate that RSU-1069 is an efficient hypoxic cell radiosensitizer and cytotoxin in this murine tumor and has little effect on well perfused ( i.e. - pubmed
Combined chlorambucil and prednisolone treatment of five patients with Wegener ' s granulomatosis . - pubmed
A modified method of culturing human amniotic fluid cells for prenatal detection of genetic disorders . - pubmed
Incidence of Linguatula serrata infection in Cairo mongrel dogs . - pubmed
Epidemiology of chronic congenital and perinatal infections of man . - pubmed
Use of an electroimmunodiffusion method on cellulose acetate films for the detection of antigenicity in human breast cancers that is related to the major core antigen of mouse mammary tumor virus ( MuMTV ) . - pubmed
Eikenella corrodens in hand infections . - pubmed
Clinical and therapeutic information on 21 patients with hand infection due to Eikenella corrodens is reported . - pubmed
A male patient , aged 7.5 years , with known sickle cell trait , presented for correction of Fallot 's tetralogy . - pubmed
A 37 - year - old man with an evolving anterior myocardial infarction received intracoronary thrombolytic therapy six hours after its onset . - pubmed
Two patients died of recurrent carcinoma at 1 and 2 3/4 years respectively . - pubmed
Three infants with malonic aciduria are reported , one of whom could be studied in detail . - pubmed
All children had severe and progressive encephalopathy with intermittent ketoacidosis and hypoglycemia . - pubmed
Biochemical studies revealed that one patient had neither malonyl - CoA decarboxylase nor glutaryl - CoA dehydrogenase deficiencies . - pubmed
This variant of malonic aciduria is different from that of four patients previously reported , both in its clinical and biochemical presentations . - pubmed
Biopsies of rectus abdominus muscle were taken from eight obese and eight control subjects undergoing elective surgery ( body mass index 52.9 + /- 3.6 vs 25.7 + /- 0.9 ) . - pubmed
Infection of cattle with bluetongue viruses in Queensland , Australia : results of a sentinel herd study , 1990 - 1992 . - pubmed
Between 1990 and 1992 , 47 sentinel herds of 10 - 20 cattle each were established throughout Queensland , Australia to monitor bluetongue virus infection . - pubmed
Only seroconversions to bluetongue virus serotypes 1 and/or 21 were detected in the study ; no evidence was found of infection with other serotyped previously isolated in Australia ( 3 , 9 , 15 , 16 , 20 , 23 ) . - pubmed
This study confirmed the presence of only serotypes 1 and 21 in Queensland and demonstrated the sporadic and restricted nature of bluetongue virus infection in the Queensland cattle herd . - pubmed
An ELISA test for the serological diagnosis of amoebic liver abscess ( ALA ) was standardized and evaluated in sera from three groups of patients : ( 1 ) three patients with diagnosis confirmed by isolation of the parasite , ( 2 ) thirty seven patients with diagnosis established by clinical findings and ultrasound studies and ( 3 ) seven patients whose diagnosis were established by clinical findings and a positive double immunodifusion test . - pubmed
Ninety one serum samples from healthy subjects and 22 from patients with other liver or parasitic diseases were also included in the study . - pubmed
Multivariate analyses between conditioned taste aversion ( CTA ) and radial maze acquisition ( RMA ) scores and percentages of neuronal dropout within thalamic and telencephalic structures were completed for rats in which overt seizures had been evoked following a single systemic injection of lithium / pilocarpine . - pubmed
DESIGN AND METHODS : One hundred and four patients with essential hypertension were classified as salt - sensitive or non - salt - sensitive depending on their blood pressure response to salt restriction . - pubmed
Gunshot wounds to the brain in children and adolescents : age and neurobehavioral development . - pubmed
Neurobehavioral outcome after craniocerebral gunshot wounds was evaluated in a prospective , 3 - year , longitudinal follow - up of a consecutive case series of 13 children and adolescents . - pubmed
At the time of follow - up , younger children sustaining gunshot wounds had slightly lower intelligence quotient scores and similar receptive language , expressive language , and gross motor scores compared with children with severe closed - head injury . - pubmed
OBJECTIVE : To evaluate the clinical significance of DNA ploidy pattern for patients with nonseminomatous germ cell testicular tumors who did not receive platinum - based chemotherapy . - pubmed
We obtained longitudinal assessments of plasma measures of dopamine ( pDA ) , norepinephrine ( pNE ) , and their metabolites , homovanillic acid ( pHVA ) and 3 - methoxy-4 - hydroxyphenylglycol ( pMHPG ) , in eight treatment - resistant or treatment - intolerant schizophrenic patients who were treated with clozapine for 12 weeks following a prolonged drug - washout period . - pubmed
Sixty - two patients with port wine stains completed a questionnaire related to their flashlamp - pumped pulsed tunable dye laser treatment . - pubmed
A 35 - year old woman with myoma of the uterus was admitted with an acute abdomen and ileus on the 16th day after delivery . - pubmed
Magnetic resonance images and audiologic data on 22 patients with NF2 who underwent multiple studies at the National Institutes of Health between 1983 and 1993 were reviewed to determine the growth characteristics of ANs in these patients . - pubmed
We reviewed the clinical characteristics , response to therapy , and long - term prognosis in 13 children ( 1.5 to 16 years of age ) diagnosed with CIDP at Washington University Medical Center , St. Louis , and the Royal Children 's Hospital , Melbourne , Australia , between 1979 and 1994 . - pubmed
Preceding events within 1 months of onset , mostly intercurrent infections or vaccinations , occurred in seven children ( 54 % ) . - pubmed
Ten children ( 77 % ) had residual weakness after an average follow - up of 6 years . - pubmed
There seems to be two populations of children with CIDP . - pubmed
One subgroup , with a favorable prognosis , progressed to peak disability over less than 3 months ; these children often have a monophasic course with complete resolution of symptoms and signs and withdrawal from all medications by 1 year after onset . - pubmed
A second subgroup progressed for 3 months or longer ; these children all required substantial does of prednisone for prolonged periods and had considerable long - term morbidity with persistent weakness . - pubmed
Cell proliferation and ploidy of human solid tumours : methodological experience with in vivo bromodeoxyuridine and DNA flow cytometry . - pubmed
The overall feasibility , together with some critical aspects of the DNA / bromodeoxyuridine ( BrdU ) in vivo assay for cell kinetic studies in human solid tumours , are reported , based on our experience in recent years . - pubmed
These findings have implications on the applicability of peptide vaccination with peptide MT(27 - 35 ) on melanoma patients . - pubmed
Overall , there was little support for the prediction of a difference in acute outcome between patients with or without pretreatment cognitive dysfunction and negative stressors . - pubmed
significantly suppressed neovascularization induced by M5076 mouse tumor cells in a mouse dorsal air sac assay system , compared to the vehicle alone ( P & lt ; 0.05 ) . - pubmed
Epithelial tumors , common in the adult , are uncommon in children and are of mild to moderate malignant potential . - pubmed
PATIENTS AND METHODS : Between May 1991 and December 1996 146 patients with biliary pancreatitis were subjected to ERCP after laboratory tests and ultrasound screening of the biliary system . - pubmed
RESULTS : Of the 70 patients with attempted LC 26 had common bile duct calculi , 23 had an impacted papillary stone and 10 had signs of a stone passage . - pubmed
However , the relative antioxidant potencies of CGP 2881 and probucol seen with oral administration to hypercholesterolemic rabbits were reversed when the compounds were given intravenously . - pubmed
In addition , the effects of these antioxidants were potentiated when given to normocholesterolemic rabbits compared to hypercholesterolemic animals . - pubmed
[ Epidemiological observations on the first case of human paragonimiasis and potential intermediate hosts of Paragonimus sp . - pubmed
Further , by various enzymatic treatments of BTV - permissive L929 cells , preliminary data have been obtained which indicated that the BTV receptor molecule(s ) is likely to be a glycoprotein and that either the protein moiety of the glycoprotein or a second protein molecule could also serve as a coreceptor for BTV infection . - pubmed
Anxiety in mice following acute aspartame and ethanol exposure . - pubmed
The results showed that rate of MP infection in COPD patients was 34.59 % . - pubmed
We discuss the pathophysiological mechanism for the induction of this rare form of thyrotoxic cardiomyopathy and emphasize that awareness of this possible presentation of hyperthyroidism is essential to identify patients with potentially reversible dilated cardiomyopathy . - pubmed
By virtue of their anatomic location in the eye , capsular - supported or sutured PCIOLs are appropriate for patients with glaucoma , diabetes , cornea guttata or low endothelial cell count , peripheral anterior synechiae , or known or suspected cystoid macular edema . - pubmed
They may also be appropriate when the patient with aphakia is young and has a relatively long life expectancy . - pubmed
Obesity modifies the relationship between ambulatory blood pressure and natriuresis in children . - pubmed
RESULTS : Weight and sodium excretion are directly associated with systolic blood pressure ; however , the relationship between blood pressure and sodium excretion seems to be modified in obese children as compared to controls . - pubmed
The interaction between sodium excretion and weight was negative indicating that the rate of change of systolic blood pressure by sodium unit is smaller for the obese than for the non - obese , even though at the same urinary sodium excretion level the obese children had higher ambulatory systolic blood pressure . - pubmed
Suppression of androgen action and the induction of gross abnormalities of the reproductive tract in male rats treated neonatally with diethylstilbestrol . - pubmed
This study evaluated whether androgen action is altered in rats treated neonatally with diethylstilbestrol ( DES ) at a dose that induced reproductive tract abnormalities . - pubmed
To test whether suppression of androgen production or action alone could induce comparable reproductive abnormalities to 10 microg DES , rats were treated neonatally with either a potent gonadotropin - releasing hormone antagonist ( GnRHa ) or with flutamide ( 50 mg / kg / day ) . - pubmed
Monocyte / macrophage activation by normal bacteria and bacterial products : implications for altered epithelial function in Crohn ' s disease . - pubmed
Intestinal immune cells are less reactive than those in the peripheral blood ; however , such cells from patients with Crohn ' s disease may be more responsive to bacterial products . - pubmed
Lamina propria mononuclear cells ( LPMCs ) and peripheral blood monocytes ( PBMs ) were obtained from patients with Crohn ' s disease and control patients . - pubmed
LPS - activated PBMs from both controls and patients with Crohn ' s disease significantly increased Isc ( approximately 300 % ) and reduced transepithelial electrical resistance ( approximately 40 % ) . - pubmed
PATIENTS AND METHODS : Twenty - five patients with nonresectable NSCLC were enrolled in an open - label , multicenter phase II study of three cycles of regimen A , carboplatin ( area under the curve , 6 ; day 1 ) plus paclitaxel ( 175 mg / m(2 ) , day 1 ) , or regimen B , cisplatin ( 100 mg / m(2 ) , day 1 ) plus vinorelbine ( 25 mg / m(2 ) , days 1 , 8 , 15 , and 22 ) in combination with intratumoral injection of 7.5 x 10(12 ) particles of SCH 58500 ( rAd / p53 , day 1 ) . - pubmed
Transgene expression was confirmed in tumor samples from 68 % of patients , and toxicities attributable to gene therapy were mild to moderate . - pubmed
Intussusception at the ileocaecocolic junction in kittens . - pubmed
This finding confirms our earlier observation that melatonin exerts a pro - apoptotic effect on murine colonic cancer cells . - pubmed
Failure of resting echocardiography and cardiac catheterization to identify pulmonary hypertension in two patients with type I Gaucher disease . - pubmed
Screening with echocardiography is recommended for Gaucher patients . - pubmed
Two patients naive to enzyme replacement therapy are presented in whom resting echocardiography revealed no evidence of PHT . - pubmed
The diagnosis of PHT was made with open lung biopsy in one patient and dobutamine echocardiography in the other . - pubmed
Resting echocardiographic assessment may fail to identify PHT in patients with Gaucher disease . - pubmed
A scar was selected for treatment in each patient and divided into four equal 2 cm segments . - pubmed
The 532 nm Q - switched Nd : YAG laser may be preferred by patients particularly distressed by the dark color of their scars . - pubmed
This has been shown in different mammalian species under experimental conditions of acute or chronic hypoxemia . - pubmed
In the present study in rats , we compared the effects of acute and chronic hypoxemia on the activity of afferents from the tibialis anterior muscle to investigate the existence of possible adaptive mechanisms to hypoxaemia . - pubmed
Chronic hypoxaemia was achieved by exposing the rats for 45 consecutive days to a gas mixture containing 10 % oxygen in nitrogen , whereas acute hypoxaemia was limited to a 1 - h exposure to a 10 % oxygen mixture . - pubmed
This may explain the observation that sensorimotor control of skeletal muscles is often markedly impaired in hypoxemic humans . - pubmed
OBJECTIVE : To assess effect of Tanshinone II A on the apoptosis of human nasopharyngeal carcinoma ( NPC ) cell line CNE-1 and inquire into the mechanism there in involved . - pubmed
A girl with rickets and nephrocalcinosis . - pubmed
This patient is an example of hypercalciuric rickets , most likely due to an inherited disorder of phosphate metabolism . - pubmed
Use of highly active chemotherapy in patients with unresectable disease ( particularly liver metastases ) achieves responses that allow a subset of patients to proceed to potentially curative surgery . - pubmed
The emergence of novel agents targeted at processes such as tumor angiogenesis will complement cytotoxic chemotherapy , while improved understanding of tumor biology should enable agents to be selected according to the likely sensitivity of the disease in a particular patient . - pubmed
[ Spores of tree lichin , Palmeria caperata L , as cause of allergic skin disease ] . - pubmed
[ Research on phenolsteroid metabolism ; chromatographic analysis of phenolsteroid metabolites in women with fibroleiomyoma of the uterus ] . - pubmed
L-3 , 4 - Dihydroxyphenylalanine ( L - dopa ) has been widely used for the treatment of Parkinson ' s disease ( PD ) , but its pharmacokinetics in the striatum have hardly been investigated , especially in primates . - pubmed
MATERIALS AND METHODS : A total of 14 oncocytomas from 12 patients were collected in 2(1/2 ) years . - pubmed
A total of 6 tumors from 5 individuals ( 46.2 % ) had chromosome 1 abnormalities . - pubmed
Structural anomalies resulting in loss of the short arm of chromosome 1 were found in an additional 2 patients . - pubmed
Comorbid depression and platelet serotonin in hemodialysis patients . - pubmed
METHODS : Comorbid depression and different clusters of depressive symptoms were assessed in 79 male HD patients and 35 male depressed psychiatric patients . - pubmed
RESULTS : Comorbid depression occurred in 50 out of 79 HD patients . - pubmed
Depressed psychiatric patients and depressed HD patients had higher scores of anxiety , retardation , and cognitive symptoms than nondepressed HD patients . - pubmed
Platelet 5 - HT concentration was lower in depressed or nondepressed HD patients than in healthy controls , or in depressed patients . - pubmed
Among HD patients , anxious HD patients had a higher platelet 5 - HT concentration than HD patients without anxiety symptoms . - pubmed
CONCLUSIONS : Comorbid depression occurred in 63 % of HD patients . - pubmed
Dialyzed patients had decreased platelet 5 - HT concentration , regardless of the occurrence of comorbid depression . - pubmed
Higher platelet 5 - HT concentration was related to anxiety symptoms in HD patients . - pubmed
Our data suggest that platelet 5 - HT concentration might be a suitable marker for anxiety symptoms in dialyzed patients . - pubmed
BACKGROUND : The Wistar Hannover rat has been considered as an alternative animal model to the Sprague - Dawley rat in the safety evaluation of candidate pharmaceuticals for potential reproductive and developmental toxicity . - pubmed
CONCLUSION : Differences in hematology and chemistry values in pregnant Wistar Hannover rats are similar to those in Sprague - Dawley rats and support use of the Wistar Hannover rat as an animal model in the assessment of maternal toxicity . - pubmed
OBJECTIVE(S ): Aim of the study was to assess the effectiveness and the complications associated with the use of tension - free vaginal tape ( TVT ) in women with stress urinary incontinence and low urethral closure pressure ( LUCP ) . - pubmed
STUDY DESIGN : Thirty - seven patients with stress urinary incontinence and LUCP who were treated with the TVT procedure have been included in the study . - pubmed
CONCLUSION(S ): Our study indicates that the TVT procedure is an effective and well - accepted minimal invasive surgery for treatment of urinary stress incontinence in women with LUCP . - pubmed
The repeated activation of a microelectromechanical systems ( MEMS ) drug delivery device was studied in vivo in rats to examine the effect of implantation on the device operation and the effect of electrochemical activation on the inflammatory and wound - healing response . - pubmed
Cysticercosis and echinococcosis cause illness and productivity losses in human and agricultural animal populations . - pubmed
To evaluate the burden , the monetary and non - monetary impacts of these zoonoses on human health , agriculture and society must be considered comprehensively . - pubmed
Mortality risk factors and validation of severity scoring systems in critically ill patients with acute renal failure . - pubmed
BACKGROUND : Risk stratification and prediction of outcome in acute renal failure patients in the intensive care unit are important determinants for improvement of patient care and design of clinical trials . - pubmed
METHODS : In order to identify mortality risks factors and validate general and specific predictive models for acute renal failure ( ARF ) patients in the intensive care unit ( ICU ) , 324 patients were prospectively evaluated . - pubmed
After delivery failed to correct her condition , a liver biopsy revealed HSV hepatitis . - pubmed
CONCLUSION : Pregnant women are susceptible to disseminated HSV causing hepatitis . - pubmed
Management of JSLE has to challenge three objectives : controlling disease progression , obtaining patient 's adherence to treatment , and preventing consequences of medication side effects on growth , puberty , development and fertility . - pubmed
BACKGROUND : Gastric electrical stimulation ( GES ) , which has been reported to have therapeutic potentials for gastroparesis and obesity , involves the surgical placement of electrodes with the patient under general anesthesia . - pubmed
Lipoproteins obtained from anorexia nervosa patients induce higher oxidative stress in U373MG astrocytes through nitric oxide production . - pubmed
BACKGROUND : The outcomes of patients with localized or locally advanced prostate cancer treated with external - beam radiotherapy are not well known in Japan . - pubmed
METHODS : Thirty - four institutions combined data on 679 patients with localized or locally advanced prostate cancer treated with a total dose & gt;/=60 Gy between 1995 and 2002 . - pubmed
RESULTS : With a median follow - up of 46 months , the 5 - year overall , clinical progression - free , and biochemical relapse - free survival rate were 93.0 , 95.3 and 71.9 % for all patients , respectively . - pubmed
Two developed Epstein - Barr virus ( EBV)-associated diffuse large B - cell lymphomas ( DLBCL ) that were clonally unrelated to the CLL . - pubmed
METHODS : A retrospective review was conducted of 236 consecutive patients who underwent anatomic lung resection for nontuberculous mycobacteria disease at our institution as part of a multimodality treatment program . - pubmed
Cerebral perfusion ( HMPAO - SPECT ) in patients with depression with cognitive impairment versus those with mild cognitive impairment and dementia of Alzheimer 's type : a semiquantitative and automated evaluation . - pubmed
PURPOSE : Comparative evaluation of regional brain perfusion measured by HMPAO - SPECT of patients with mild cognitive impairment ( MCI ) , dementia of Alzheimer 's type ( DAT ) and depression with cognitive impairment ( DCI ) . - pubmed
METHODS : A total of 736 patients were investigated because of suspected cognitive dysfunction . - pubmed
After exclusion of patients with other forms of dementia than DAT or relevant accompanying disorders , SPECT data from 149 MCI , 131 DAT and 127 DCI patients , and 123 controls without any cognitive impairment , were analysed . - pubmed
Compared to controls DCI patients showed hypoperfusion of the thalamus , lentiform nucleus and medial temporal cortex . - pubmed
MCI patients differed significantly from controls concerning perfusion in both hemispheric temporal and parietal areas , and in the ( right hemispheric ) posterior part of the cingulate gyrus . - pubmed
MCI and DCI patients differed in the parietal , temporal superior and right hemispheric cingulate gyrus posterior cortices . - pubmed
Global forebrain and regional perfusion was more extensively reduced in DAT patients and discriminated them from controls , and MCI and DCI patients . - pubmed
CONCLUSION : Automated analysis of HMPAO - SPECT data from MCI patients showed significant perfusion deficits in regions also involved in DAT patients , but ROC analysis demonstrated only moderate sensitivity and specificity for differentiating DAT patients from controls and DCI patients . - pubmed
Finally , the results in DCI patients again raise the question of depression as an early symptom of neurodegeneration . - pubmed
SUBJECTS AND METHODS : The study group consisted of 80 OLP patients and 80 healthy individuals . - pubmed
Other factors , related to the etiopathogenesis of Parkinson ' s disease or to patients ' endophenotypes , are beginning to be identified . - pubmed
Gastropericardial fistula and Candida albicans pericarditis : a rare complication of gastric adenocarcinoma treated with radiation and chemotherapy . - pubmed
We report a 47 - year - old man with gastric adenocarcinoma who had completed radiotherapy and was on scheduled chemotherapy , who presented with fever and chest pain . - pubmed
Gastric adenocarcinoma complicated with gastropericardial fistula and Candida albicans pericarditis were diagnosed and treated successfully with conservative management . - pubmed
This case demonstrates that first , panendoscopy may be safely performed in patients with gastropericardial fistula without significant risk of cardiac tamponade ; second , although early diagnosis of gastropericardial fistula is generally important , delayed recognition may not lead to devastating outcomes even in the absence of surgical intervention . - pubmed
Episodic vomiting and headache in children : consider occipital epilepsy . - pubmed
Children with occipital seizures often have ictal autonomic symptoms such as pallor and vomiting and lack motor manifestations . - pubmed
This has lead to misdiagnosis of occipital seizures in children . - pubmed
The following case report highlights the clinical features of a child with occipital epilepsy misdiagnosed as having migraine . - pubmed
BACKGROUND : The potential for transmission of Mycobacterium tuberculosis during air travel has garnered considerable attention in the media and among public health authorities due to high - profile cases of international travelers with infectious tuberculosis ( TB ) . - pubmed
Herein , we report the cases of 2 patients who had malignant ventricular arrhythmias secondary to ischemic heart disease . - pubmed
Acute inflammation was induced in mice and intestines were analyzed by biochemical and histologic methods . - pubmed
In vitro cytotoxicity of the chlorinated naphthoquinone dichlone to human endothelial ECV304 cells . - pubmed
The sensitivity of these cells to dichlone was intermediate between that of human hepatoblastoma HepG2 cells ( least sensitive ) and that of human GMO5757 fibroblasts . - pubmed
The later class of compounds reduces remarkably plasma triglycerides , total cholesterol and LDL - cholesterol in hyperlipidemic rats . - pubmed
The medical records of 237 patients with invasive breast cancer who underwent surgery between 1995 and 2006 were reviewed . - pubmed
These cases included 10 patients ( 4.2 % ) with mucinous carcinoma . - pubmed
The tumor size was T1 in 5 patients and T2 in 5 patients . - pubmed
Treatment of disfiguring chronic graft versus host disease in a child with topical pimecrolimus . - pubmed
Even though Mycobacterium tuberculosis ( Mtb ) remains one of the top microbial killers , more than 90 % of the 2 billion infected individuals never develop active tuberculosis ( TB ) , indicating efficient immune control of infection in these individuals . - pubmed
An important preliminary step in the diagnosis of leukemia is the visual examination of the patient 's peripheral blood smear under the microscope . - pubmed
For over ten years , chemotherapy with gemcitabine has been standard treatment for those patients with advanced pancreatic cancer , prolonging survival by only 5 - 6 months . - pubmed
Over the past several years , a number of phase II and phase III trials have combined gemcitabine with these novel treatments , with the hope of prolonging survival in patients with pancreatic cancer . - pubmed
MATERIAL AND METHODS : The survival rates of testicular cancer patients were evaluated using the data of the Lithuanian Cancer Registry for 1998 - 2002 . - pubmed
CONCLUSIONS : The survival of patients with testicular cancer in Lithuania was substantially lower than in other European countries . - pubmed
Anterior surgery in selective patients with massive ossification of posterior longitudinal ligament of cervical spine : technical note . - pubmed
CONCLUSION : Anterior surgery using our technique may be a relatively simple and safe procedure in selective patients with massive ossification of posterior longitudinal ligament of cervical spine . - pubmed
Central lymph node metastases are a very common problem in WDTC , being present in up to 90 % of patients . - pubmed
This study was performed to determine the influence of tumor grade and histology on the glycolytic phenotype of epithelial ovarian cancer patients . - pubmed
MATERIAL AND METHODS : We identified 238 patients with squamous intraepithelial lesions / cervical intraepithelial neoplasia ( CIN ) who were treated by loop electrocautery excision ( LEEP ) or conventional cold - knife conization ( CKC ) . - pubmed
Samples collected from the Andhra Pradesh coast displayed a slightly higher prevalence of WSSV and MBV infection than those collected from Tamil Nadu , although this difference was not statistically significant ( P & gt ; 005 ) . - pubmed
In addition , it was found that the prevalence of both WSSV and MBV infections fluctuated according to season . - pubmed
The aim of our study was to screen for liver disease among type 1 diabetic children . - pubmed
METHODS : Children with type 1 diabetes following in clinic have been examined for existence of liver disease , from November 2008 to November 2009 . - pubmed
RESULTS : 106 children with type 1 diabetes were studied : age ranged between 8 months to 15.5 years , sixty two patients were females . - pubmed
Twenty two patients ( 21 % ) were identified to have abnormal findings on ultrasound of the liver : 10 patients had hepatomegaly and 12 had hyperechogenic liver . - pubmed
CONCLUSIONS : Hyperechogenic liver and/or hepatomegaly are not uncommon in children with type 1 diabetes and tend to be more prevalent among children with poor glycemic control . - pubmed
Because of its safety , and reliability , ultrasound can be used to screen for hepatopathy in type 1 diabetic child . - pubmed
Methadone for chronic non - cancer pain in adults . - pubmed
Both RCTs were cross - over studies , one involving 19 participants with diverse neuropathic pain syndromes , the other involving 76 participants with postherpetic neuralgia . - pubmed
The non - randomized study found that in patients initially prescribed methadone it was effective in fewer participants than in those initially prescribed other long - acting opioids ( 28 % versus 42 % , 33 % and 50 % for morphine , oxycodone and transdermal fentanyl , respectively).One RCT compared incidences for several individual adverse events , but found a difference between methadone and placebo for only one event , dizziness ( P = 0.041 ) . - pubmed
CASE REPORT : The authors report the case of a woman with recent - onset grade I hypertension , who was referred to our staff for sonographic studies of the kidneys and urinary tract . - pubmed
The case reported here underlines the importance of using color Doppler ultrasound when obstructive uropathy is suspected , especially in patients who have undergone renal biopsy . - pubmed
An international longitudinal registry of patients with atrial fibrillation at risk of stroke ( GARFIELD ): the UK protocol . - pubmed
Reconstruction of a collapsed dental arch in a patient with severe periodontitis . - pubmed
A Japanese man ( age , 40 years 7 months ) had an anterior crossbite , a collapsed occlusion , and severe periodontitis . - pubmed
Here , we study the genetic cause of his albinism and making use of whole genome sequencing data we find a higher inbreeding coefficient compared to other gorillas . - pubmed
This transporter is known to be involved in oculocutaneous albinism type 4 ( OCA4 ) in humans . - pubmed
The demographic and clinical features of the patients , birth complications , infection rates and rates of neonatal intensive care unit attendance were evaluated . - pubmed
Birth trauma was observed in three patients ( 1.6 % ) as one brachial nerve paralysis , one cord rupture and one cephal hematoma . - pubmed
Prognostic factors in elderly osteosarcoma patients : a multi - institutional retrospective study of 86 cases . - pubmed
BACKGROUND : The occurrence of osteosarcoma in elderly patients has recently been increasing , and the outcome is poor . - pubmed
This multi - institutional retrospective study was conducted to investigate clinical features and prognostic factors in patients older than 40 years with osteosarcoma . - pubmed
METHODS : Patients with conventional high - grade osteosarcoma older than 40 years were recruited to this study . - pubmed
Although patients without metastasis who received definitive surgery were regarded as good candidates for chemotherapy , the addition of chemotherapy did not have any impact on the outcome ( yes 63.4 % ; no 65.2 % ; p = 0.511 ) . - pubmed
CONCLUSIONS : The present study revealed the distinct clinical features , such as the high incidence of truncal tumors or metastasis at diagnosis , in patients older than 40 years with osteosarcoma . - pubmed
Efficacy and safety of renal denervation in elderly patients with resistant hypertension . - pubmed
Elderly patients with rHTN should not be excluded from renal denervation . - pubmed
Out of these , 33 ( 75 % ) , 36 ( 51.4 % ) , and 48 ( 73.8 % ) from wounds , skin , and bed , respectively , were found to be methicillin - resistant Staphylococcus aureus ( MRSA ) using the disc - sensitive test methods . - pubmed
The proportion of patients with symptomatic gastroesophageal reflux disease increased from 12.8 % to 27.4 % . - pubmed
Our study provides a new rationale for combining metronomic chemotherapy with adoptive cell immunotherapy in the treatment of xenograft NSCLC tumors in immunodeficient mice . - pubmed
Viridans streptococci were the most common cause of IE ( 32 % ) , followed by Staphylococcus aureus ( 24 % ) . - pubmed
The risk of stroke was higher in those with endocarditis caused by S. - pubmed
As part of that effort , the Agency will need to address the fact that while a National Toxicology Program ( NTP ) chronic inhalation bioassay of V2O5 produced clear evidence of treatment - related lung tumors in both male and female B6C3F1 mice , neither of these responses were dose - related across the groups exposed to 1 , 2 , and 4mg / m(3 ) . - pubmed
Herein we report results from computing poly-3 - adjusted Cochran - Armitage trend test statistics with and without inclusion of the lung tumor incidence data from control group mice . - pubmed
These results confirm the absence of any significant dose - related effect on mouse lung tumor incidence in the study groups exposed to V2O5 . - pubmed
This prescription must consider contraindications and medical conditions for safe insertion , especially to avoid infection by screening STD ( Chlamydia trachomatis and Nesseria gonorrhoeae ) in nulliparous women<25 years old . - pubmed
This report presents use of presurgical compression and prophylactic passive pressure therapy with acrylic appliances for auricular keloids in a patient . - pubmed
Her hospital course included Staphylococcus epidermidis bacteremia , for which broad spectrum antibiotics were prescribed . - pubmed
Three previously treated ATL patients , classified as intermediate- to high - risk , were subcutaneously administered with the vaccine , consisting of autologous dendritic cells ( DCs ) pulsed with Tax peptides corresponding to the CTL epitopes . - pubmed
Shigella is the main cause of bacillary dysentery with around 160 million annual cases , while EIEC generally induces a milder disease compared to Shigella . - pubmed
Caenorhabditis elegans killing- and bacterial colonization assays were performed to examine the potential difference in virulence between Shigella and EIEC strains . - pubmed
Shigella dysenteriae serotype 1 which carries the Shiga toxin showed the lowest nematode survival rate at 82.6 + - 3.97 % and highest bacterial colonization of 1.75 x 10(5 ) + - 8.17 x 10(4 ) CFU ml(-1 ) , whereas a virulence plasmid - negative Shigella strain demonstrated 100 + - 0 % nematode survival and lowest bacterial accumulation of 1.02 x 10(4 ) + - 7.23 x 10(2 ) CFU ml(-1 ) . - pubmed
Efficacy of edaravone on coronary artery bypass patients with myocardial damage after ischemia and reperfusion : a meta analysis . - pubmed
METHODS : We included randomized controlled trials that compared edaravone with placebo or no intervention in patients with acute myocardial infarction or undergoing coronary artery bypass . - pubmed
Risk of oral and gastrointestinal mucosal injury in patients with solid tumors treated with everolimus , temsirolimus or ridaforolimus : a comparative systematic review and meta - analysis . - pubmed
BACKGROUND : The authors performed a systematic review and meta - analysis of diarrhea and stomatitis associated with the use of everolimus , temsirolimus or ridaforolimus in patients with solid tumors . - pubmed
PATIENTS AND METHODS : Eligible studies included randomized trials of patients with solid tumors on everolimus , temsirolimus or ridaforolimus , describing the events of diarrhea and stomatitis . - pubmed
We examined patterns of cortical thickness loss and cognitive decline over time in 19 patients with Alzheimer ' s disease ( AD ) , 10 with behavioral variant frontotemporal dementia ( bvFTD ) , and 34 controls with a mean interval of 2.1 + - 0.4 years . - pubmed
Decrease of thickness over time was highest in AD and generalized throughout the whole brain , most pronounced posteriorly , whereas bvFTD patients had a more selective loss in frontal cortex and in anterior parts of the temporal lobes . - pubmed
In a direct comparison , AD patients showed faster cortical thinning in the insula , temporal , and parietal regions , whereas bvFTD patients only showed faster cortical thinning in the orbitofrontal gyrus . - pubmed
Decline of cognitive performances was in line with cortical thinning and deteriorated the most in AD patients . - pubmed
Despite promising short - term results and emerging arthroscopic techniques , it remains unclear whether patients benefit from surgical correction in the mid- to long - term and whether progressive joint degeneration can be prevented . - pubmed
Of these 44 patients , 39 were treated with correction of the femoral offset for isolated cam deformity , 5 with additional focal pincer correction and partial labral resection . - pubmed
CONCLUSIONS : Arthroscopic correction of femoroacetabular impingement results in a persistent clinical improvement without significant progression of degenerative changes in the majority of patients . - pubmed
Clinical profile of patients with traumatic cervical spine injury in the emergency department of a tertiary care hospital . - pubmed
However , studies in human revealed that prolonged consumption of this plant led to dependence and tolerance while cessation caused a series of aversive withdrawal symptoms . - pubmed
PURPOSE : The purpose of this study was to determine the efficacy and feasibility of surgical management of children with thoracolumbar spine tuberculosis with kyphosis by using one - stage posterior focus debridement , interbody grafts , and posterior instrumentation and fusion . - pubmed
METHODS : From October 2010 to September 2013 , 21 children with thoracolumbar spinal tuberculosis accompanied by kyphosis were treated with one - stage posterior decompression , interbody grafts , and posterior instrumentation and fusion . - pubmed
Patients were evaluated before and after surgery in terms of ESR , neurologic status , pain , and kyphotic angle . - pubmed
RESULTS : Spinal tuberculosis was completely cured , and the grafted bones were fused in all 21 patients . - pubmed
Pain relief was obtained in all patients . - pubmed
CONCLUSIONS : Our results show that one - stage posterior decompression , interbody grafts , and posterior instrumentation and fusion were an effective treatment for children with thoracolumbar spinal tuberculosis . - pubmed
METHODS : The records of 432 patients with RCC who underwent radical or partial nephrectomy between 2005 and 2014 were retrospectively reviewed . - pubmed
BACKGROUND : Trauma - induced coagulopathy ( TIC ) is commonly seen among patients with severe injury . - pubmed
RESULTS : We identified 53 patients with a diagnosis of sub - epidermal autoimmune blistering disease . - pubmed
Twenty - eight patients had abnormal values of eosinophilia , extremely susceptible to systemic steroid therapy . - pubmed
Allergic contact dermatitis caused by panthenyl ethyl ether in a patient with psoriasis . - pubmed
In this study , we used stochastic dynamic causal modeling ( sDCM ) to quantify connections among the left dorsolateral prefrontal cortex ( inner speech monitoring ) , auditory cortex ( auditory processing ) , hippocampus ( memory retrieval ) , thalamus ( information filtering ) , and Broca 's area ( language production ) in 17 first - episode drug - naive SZ patients with AVHs , 15 without AVHs , and 19 healthy controls using resting - state functional magnetic resonance imaging . - pubmed
sDCM revealed an increased sensitivity of auditory cortex to its thalamic afferents and a decrease in hippocampal sensitivity to auditory inputs in SZ patients with AVHs . - pubmed
CONTEXT : Two - thirds of patients undergoing coronary artery bypass grafting ( CABG ) surgery report moderate to severe pain , particularly with ambulatory or respiratory effort . - pubmed
The pain was assessed at 4 h after extubation when the patient was fully awake , then at 8 , 12 , 18 , and 24 h. Both groups received intravenous tramadol 100 mg as rescue analgesia whenever visual analog scale score was 5 and above . - pubmed
This study aimed to develop a predictive model of POAF based on preoperative transthoracic echocardiography ( TTE ) findings in these patients . - pubmed
Results : Thirty - seven ( 12 % ) patients developed POAF . - pubmed
Copper accumulation in parts of the brain accompanied by some neurologic involvement was revealed in LEC rats and tx / tx - j mice , but the pathology is less severe than human neurologic WD . - pubmed
Several dogs show hepatic copper toxicity resembling WD ; however , brain involvement has not been observed and the underlying genetic defect is different . - pubmed
Findings made by animal studies may facilitate the development of specific therapies to ameliorate WD progression . - pubmed
Pathogenic endoparasites of the spotted seatrout , Cynoscion nebulosus : patterns of infection in estuaries of South Carolina , USA . - pubmed
Six types of pathogenic endoparasites in an economically important fish , spotted seatrout Cynoscion nebulosus , were studied in order to test whether prevalence of infection and assemblage richness varied with season , host sex , host size , or host age . - pubmed
Treatment adherence during childhood in individuals with phenylketonuria : Early signs of treatment discontinuation . - pubmed
Analyze how treatment adherence evolves through infancy , childhood , and early adolescence in individuals with PKU . - pubmed
Individuals can be either CD177 - deficient or harbor distinct CD177neg and CD177pos neutrophil subsets . - pubmed
vignicola strains cause bacterial blight of the legume crop cowpea . - pubmed
Changes in gene expression in chronic allergy mouse model exposed to natural environmental PM2.5 - rich ambient air pollution . - pubmed
In the present study , we aimed to investigate the cellular responses induced by exposure to natural ambient air pollution , employing a mouse model of chronic allergy . - pubmed
Significantly higher frequencies of anemia , hematinic deficiencies , hyperhomocysteinemia , and serum gastric parietal cell antibody positivity in atrophic glossitis patients . - pubmed
Of the 202 anemic AG patients , 22 had pernicious anemia , eight had macrocytic anemia rather than pernicious anemia , 117 had normocytic anemia , 30 had iron deficiency anemia , and 21 had thalassemia trait - induced anemia , and four had microcytic anemia rather than iron deficiency anemia and thalassemia trait - induced anemia . - pubmed
The normocytic anemia and iron deficiency anemia are the two most common types of anemia in our 1064 AG patients . - pubmed
PURPOSE : Patients with localized muscle - invasive bladder cancer ( MIBC ) can choose to undergo either neoadjuvant chemotherapy followed by radical cystectomy or radiation therapy - based bladder preservation treatment modality with subsequent close cystoscopic surveillance with salvage cystectomy reserved for patients with evidence of local disease recurrence . - pubmed
Once validated , biological markers will help clinicians tailor the management of MIBC to individual patients . - pubmed
Accumulating evidence suggests that microRNA-326 ( miR-326 ) serves as a tumor suppressor in the initiation and progression of several human malignancies . - pubmed
Downregulation of miR-326 was closely associated with aggressive progression and poor prognosis of primary PCa patients . - pubmed
Overexpression of miR-326 also suppressed tumor growth in xenografted nude mice in vivo . - pubmed
RESULTS : We identified 129 HHD patients ; 104 ( 81 % ) were followed for & gt;=6 months . - pubmed
With relatively rapid training , HHD should be considered in more patients . - pubmed
Here , we report the annotated draft genome sequences of six type strains of the family Eggerthellaceae , Gordonibacter faecihominis JCM 16058 , Paraeggerthella hongkongensis DSM 16106 , Parvibacter caecicola DSM 22242 , Slackia equolifaciens DSM 24851 , Slackia faecicanis DSM 17537 , and Slackia isoflavoniconvertens DSM 22006 . - pubmed
The obesity - increased macrophage infiltration and lipotoxicity was decreased in mouse kidney after miR-155 sponge treatment . - pubmed
Neuroanatomical and functional alterations of insula in mild traumatic brain injury patients at the acute stage . - pubmed
To explore this hypothesis , we investigated early alterations in the gray matter volume ( GMV ) and brain functional connectivity ( FC ) of insula in mTBI patients within 7 days after injury and any possible correlations with cognitive function . - pubmed
A total of 58 mTBI patients at the acute stage and 32 matched healthy controls were recruited and underwentT1 - weighted magnetic resonance imaging ( MRI)andresting - state functional MRI scans within 7 days of injury . - pubmed
We found that the GMV was significantly reduced only in the right insula in mTBI patients and no significant GMV increase was observed in either hemisphere . - pubmed
mTBI patients demonstrated decreased FC in the right parahippocampal gyrus and increased FC in the right supramargianl gyrus . - pubmed
In addition , compared to the healthy controls , the mTBI patients in the acute stage presented a decline in the visuospatial / executive ( p = 0.013 ) and attention ( p = 0.038 ) subcategories . - pubmed
Our data demonstrated alterations of the GMV and resting - stateFC of the right insula in mTBI patients at the acute stage . - pubmed
Mouse Model of Mutated in Colorectal Cancer Gene Deletion Reveals Novel Pathways in Inflammation and Cancer . - pubmed
davaonensis was not observed in recombinant strains of B. - pubmed
14 mg / l ) roseoflavin was produced with recombinant strains of C. - pubmed
A description is given of a patient suffering from MD1 with a number of endocrine disorders , including hypergonadotropic hypogonadism , autoimmune thyroid disease , hyperinsulinism , and also impaired calcium - phosphorus metabolism . - pubmed
Patients with PMV were associated with increased blood transfusions , more consumption of vasopressin and antipulmonary hypertension medication , higher incidence of reintubation , more renal replacement treatment , longer intensive care unit stay , greater hospitalization costs , and more specialist visits . - pubmed
METHODS : Phase I , randomized , double - blind , single - dose , three - period , six - sequence cross - over , multi - center study to evaluate the pharmacokinetics , pharmacodynamics , safety , and immunogenicity of Sandoz biosimilar pegfilgrastim with US- and EU - references in healthy adults . - pubmed
CASE PRESENTATION : A 27 - year - old woman at 31 + 5 weeks ' gestation presented to the emergency department with a three - day history of the left lower abdominal pain . - pubmed
With the provisional diagnosis of adnexal torsion , the patient was taken to surgery . - pubmed
Brucellosis is a serious zoonosis occurring mainly in developing countries , and its diagnosis is largely dependent on serologic detection and bacterial culture . - pubmed
The high stability of the tested agents in human plasma will most likely result in long - lasting poisoning in vivo , having relevant consequences for the treatment regimen . - pubmed
An echocardiogram was performed in 170 hypertensive patients and 20 healthy individuals . - pubmed
The Impact of Beta Blockers on Survival Outcomes in Patients With Non - small - cell Lung Cancer Treated With Immune Checkpoint Inhibitors . - pubmed
We investigated patients with lung cancer who concomitantly used beta blockers and immune checkpoint inhibitors ( ICIs ) , with the hypothesis that beta blockade would positively impact clinical outcomes . - pubmed
PATIENTS AND METHODS : We retrospectively reviewed the health records of 109 patients who were treated at Northwestern University from January 2014 through August 2018 with ICIs for non - small - cell lung cancer ( NSCLC ) . - pubmed
RESULTS : Among 109 patients treated with ICIs for NSCLC , 28 of them were concomitantly prescribed beta blockers . - pubmed
CONCLUSIONS : Our data suggests beta blocker use may be associated with improved PFS among patients treated with ICIs for NSCLC . - pubmed
Methods : In the current study , we evaluated resting - state functional MRI ( rsfMRI ) data and neuropsychological assessments for various cognitive functions in a cohort with 84 early PD patients from the Parkinson 's Progression Markers Initiative ( PPMI ) . - pubmed
Results : Our study demonstrated that in the early PD patients , scores of Letter Number Sequencing ( LNS ) were positively correlated with EC in the left inferior occipital gyrus ( IOG ) and lingual gyrus . - pubmed
Influence of Omega-3 Fatty Acid - Rich Fish Oils on Hyperlipidemia : Effect of Eel , Sardine , Trout , and Cod Oils on Hyperlipidemic Mice . - pubmed
The anti - hyperlipidemic effect of selected fish oils ( eel , sardine , trout , cod liver ) was comparatively evaluated in a high fat diet ( HFD)-fed mouse model . - pubmed
At the end of 30 days on the HFD , all animals were hyperlipidemic and were switched to a diet consisting of 90 % standard rodent chow plus 10 % of oil from eel , sardine , cod liver , or trout . - pubmed
The fish oils tested here for effects on hyperlipidemia vary in per cent of omega-3 FAs and omega-6 /- 3 FA ratios as determined by gas chromatography Overall , smoked eel was the best source of omega-3 FA , with a balance of omega-6 FA , that ameliorated HFD - induced mixed hyperlipidemia . - pubmed
OBJECTIVE : The cytotoxic effect of bersaldegenin-1,3,5 - orthoacetate - a bufadienolide steroid occuring in plants from Kalanchoe genus ( Crassulaceae ) , was evaluated with cervical cancer HeLa cells in vitro . - pubmed
We aimed to investigate the associations of the level and increase in D - dimer between baseline and 90 days with all - cause death or poor functional outcome in patients after ischemic stroke or transient ischemic attack . - pubmed
The present substudy included 10 518 patients within 7 days ( baseline ) of ischemic stroke or transient ischemic attack and 6268 patients at 90 days . - pubmed
Conclusions Our study shows that high level and an increase in D - dimer between baseline and 90 days are associated with poor outcomes in patients after ischemic stroke or transient ischemic attack . - pubmed
Results : The Korean patients with MacTel type 2 were predominantly female ( 75 % ) , and the mean logMAR visual acuity was 0.282 + - 0.280 at initial presentation . - pubmed
The objective of this study is to determine whether middle - aged adults prescribed a low carbohydrate - high fat ( LCHF ) or low fat ( LF ) diet would have greater loss of central fat and to determine whether the insulin resistance ( IR ) affects intervention response . - pubmed
Evidence of hyperthyroidism such as weight loss , elevation of rectal temperature , increased heart rate and oxygen consumption , was observed in all treated rats . - pubmed
1,4,5,6,8 - Pentaazaacenaphthylene-3 - amino-1,5 - dihydro-5 - methyl -( 5 - 14C )- 1 - beta - D - ribofuranysly ( NSC-154020 ) , a tricyclic 7 - deazapurine nucleoside ( TCN ) , was rapidly incorporated into the acid - soluble pool by cultured Novikoff rat hepatoma cells , mouse L - cells , HeLa cells , and HEp-2 cells , but little incorporation into nucleic acids occurred . - pubmed
Netilmicin , a new aminoglycoside antibiotic , has increased in vitro bactericidal activity against many strains of Enterobacteriaceae as compared to other aminoglycosides . - pubmed
No ototoxicity was observed in two patients whose treatment required inordinately high serum levels and in whom other risk factors were present . - pubmed
Ototoxicity in 1 of 21 patients studied was unilateral , partially reversible , and not associated with high serum levels . - pubmed
Although nephrotoxicity occurred in 4 of 25 patients ( 16 % ) , other host factors could have accounted for the toxicity in two patients . - pubmed
Long - term follow - up of twenty - six patients with unicameral bone cysts treated by curettage and packing with plaster - of - Paris pellets showed a recurrence in only two cases and no serious complications . - pubmed
Reticulo - endothelial phagocytosis in patients with nephritis . - pubmed
In Nallur , which was endemic for JE and had a large pig population , 4.4 - 5.4 % of the feedings were on these hosts . - pubmed
By intravenous application of the specific Quisqualate antagonist glutamic acid diethyl ester ( GDEE ) 77.2 % of our patients with cochlear synaptic tinnitus noted a tinnitus reduction . - pubmed
The dimensions of the aneurysms ( transversal diameter and length ) were greater in hypertensive than in normotensive animals ( F = 11 , P less than 0.001 ) and aneurysmal dimensions were positively correlated with the level of blood pressure ( r = 0.56 , P less than 0.001 ) . - pubmed
Protection by schisanhenol against adriamycin toxicity in rat heart mitochondria . - pubmed
The effects of schisanhenol ( Sal ) on Adriamycin ( ADM)-induced rat heart mitochondrial toxicity in vitro were investigated . - pubmed
These results indicate that Sal could protect against ADM - induced rat heart mitochondrial toxicity . - pubmed
The content of cyclic nucleotides in blood plasma was measured in 151 patients suffering from rheumatoid arthritis . - pubmed
RA patients untreated with glucocorticoids manifested significant correlations between the content of cyclic nucleotides and some characteristics of inflammation and of the immune status . - pubmed
Treatment with 1 alpha - hydroxyvitamin D3 and phosphates was associated with acceleration of growth in all children , healing of rickets in 21 , and normalization of the serum phosphate in 22 . - pubmed
This study was undertaken to evaluate the efficacy and the safety of transnasal butorphanol ( TNB ) compared to intravenous butorphanol ( IVB ) in 186 patients experiencing moderate to severe post - cesarean section pain . - pubmed
High therapeutic efficacy was demonstrated in experimental mice septicemias with the 2 -( 3 - pyridyl ) derivative 2b and its orally absorbed acetoxymethyl ester prodrug 4n . - pubmed
A single episode of systemic capillary leak syndrome is reported in a HIV - positive patient . - pubmed
Therefore , it appears reasonable to monitor muscular pressure during volume expansion in patients with capillary leak syndrome , severe shock and muscular swelling . - pubmed
The possibility can not be excluded that the natural exposure of humans to SPM in the environmental atmosphere may explain the high prevalence rate of allergic rhinitis caused by pollens in polluted districts in Japan . - pubmed
After DR for various periods , kittens were subsequently exposed to light so as to trigger the onset of the CP that had been postponed . - pubmed
One is a 45 - year - old man with Philadelphia - positive CML , and the other a 74 - year - old patient with Philadelphia - negative CML . - pubmed
The test is therefore likely to be of value in the correct diagnosis of the cause of renal dysfunction and thereby improve the management of cyclosporine - treated renal transplant patients . - pubmed
All four patients in this study had a cardiomyopathy , and heart disease was the cause of death in two of the patients . - pubmed
Like radioimmunoassay , immunoenzyme assay permits detecting myoglobinemia both in healthy persons and in patients with acute myocardial infarction ( AMI ) . - pubmed
In AMI patients , myoglobinemia reaches a maximum 5 to 12 hours since the onset of a powerful anginal attack whereupon it gradually and spasmodically decreases , without returning to normal toward outcome of the 3d day of the observation period . - pubmed
A single assay of myoglobinemia in AMI patients is of diagnostic importance within 2 to 27 hours since the disease onset . - pubmed
After three to four hours of treatment , hypan achieved greater cervical dilation among primigravid women and only modestly increased side effects , as compared with 16 dimethyl PGE2 suppositories or laminaria tents . - pubmed
Obese patients showed no significant differences from controls in basal and nadir glucose , basal and peak glucagon , cortisol , and thyroid responses to both tests . - pubmed
The brains of all three patients with developmental dyslexia studied thus far have shown scattered small malformations primarily in the cerebral cortex of the left cerebral hemisphere . - pubmed
In view of the possible involvement of these systems in learning suggested by these and by previous data , it seems likely that the neurohumoral regulation of habituation and avoidance learning may be different in rats submitted to protein malnutrition when compared to controls . - pubmed
Anatomic - ultrasound correlations for intraoperative open chest imaging of coronary artery atherosclerotic lesions in human beings . - pubmed
Ultrasound images of coronary atherosclerotic lesions were compared with anatomic specimens of the coronary arteries obtained from open chest human subjects . - pubmed
The anatomic specimens were derived from four cardiac transplant recipients , accepted as candidates for transplantation because they had severe diffuse atherosclerotic disease , and one patient who died in the early postoperative period after a coronary artery bypass procedure . - pubmed
Twenty - six ultrasonically imaged atherosclerotic areas of the coronary arteries in these patients were compared with formalin - fixed and decalcified anatomic specimens . - pubmed
The management of common bile duct calculi by endoscopic sphincterotomy in patients with gallbladders in situ . - pubmed
Endoscopic sphincterotomy ( ES ) is widely used in the treatment of patients with common bile duct ( CBD ) stones following cholecystectomy . - pubmed
In Group A 5 patients required surgery , in 3 because of technical failure and in 2 because of empyema of the gallbladder . - pubmed
On follow - up ( 4 - 50 months ) , 16 patients have died but in only one from gallbladder sepsis , and one has had a cholecystectomy for pain . - pubmed
Arterial blood flow and resistance in the forearm of arteriosclerotic patients . - pubmed
Twenty patient with severe atherosclerotic affection of the lower limbs , but without any symptoms of involvement of their upper extremities , and twenty healthy controls were examined . - pubmed
The resistance of mice to a lethal infection with Klebsiella pneumoniae , type I , was investigated . - pubmed
This antigen does not appear to be related to either the K or O antigens of Klebsiella and is present in several strains of Klebsiella . - pubmed
Ophthalmologists treating children with retinoblastoma need to be aware of the limitations of new forms of therapy and their complications . - pubmed
For this reason the following case of a child with a small peripheral retinoblastoma that failed to respond to treatment with both cryotherapy and photocoagulation is recorded . - pubmed
Naturally occurring and chemically induced brain tumors of rats and mice in carcinogenesis bioassays . - pubmed
Passive transfer of insulitis from the " BB " rat to the nude mouse . - pubmed
The " BB " rat spontaneously develops insulitis , and an insulin - dependent diabetic syndrome like that in man . - pubmed
Of 72 mice receiving single injections 37 % showed insulitis , with 13 % of islets examined being affected , and mean intensity of 1.9 + /- 0.3 ( on a scale of 0 to 3 ) . - pubmed
In 12 mice receiving 3 separate injections of pooled blood and spleen lymphocytes , 58 % showed insulitis , with 17 % of islets affected , and mean intensity 2.5 + /- 0.3 . - pubmed
Because cocaine blocks uptake of catecholamines and has a sympathetic potentiating effect , its use is dangerous in patients with hypertensive cardiovascular disease or in conjunction with sympathomimetic or alpha - modifying drugs . - pubmed
We encountered two patients with indolent chronic B - cell leukemia showing overlapping features of these malignancies . - pubmed
PATIENTS : Consecutive series of 37 patients ; 29 with chronic sinusitis , five with chronic dacryocystitis , one with recurrent choanal stenosis , one with tracheopathia osteoplastica , and one with a sphenoid sinus mucocele . - pubmed
RESULTS : Complications occurred in eight patients : intranasal or ethmoid scarring ( four ) , persistent polyps ( one ) , bleeding ( one ) , stent dislodgment ( one ) , and tracheitis ( one ) . - pubmed
This study was undertaken to expand the current knowledge of the life cycle and adult morphology of the avian schistosome Austrobilharzia variglandis , which causes a marine cercarial dermatitis in New England . - pubmed
The specific objectives were to : ( 1 ) investigate the seasonality of the infection in the molluscan intermediate host , Ilyanassa obsoleta ; ( 2 ) determine which bird species are acting as natural definitive hosts for the parasite ; and ( 3 ) characterize the morphology of the parasite using scanning electron microscopy ( SEM ) . - pubmed
Ilyanassa obsoleta was found to maintain a relatively low prevalence of infection ( 0.7 - 5.1 % ) throughout the 14 - mo study , but no fully developed cercaria were visible in sporocysts recovered from snails collected in winter months . - pubmed
For the purpose of follow - up of the disease as well as the availability of magnetic resonance imaging ( MRI ) as a method for diagnosing soft tissue changes 20 patients with imminent and manifest compartment syndrome were examined for their fluid content of the lower limb . - pubmed
The patients with imminent compartment syndrome and fasciotomy ( r = 0.83 , p & gt ; 0.001 , n = 19 ) demonstrated no significant changes compared to the normal volunteers ( r = 0.91 , p & gt ; 0.001 , n = 40 ) as well as the normal compartments of the diseased lower extremities ( r = 0.85 , p & gt ; 0.001 , n = 32 ) . - pubmed
OBJECTIVE : To describe a series of consecutive patients with fulminant hepatic failure ( FHF ) and to present a new classification system for brain edema , an important cause of mortality in such patients . - pubmed
DESIGN : We reviewed 22 computed tomographic ( CT ) scans of the brain in 12 patients with FHF and classified the severity of cerebral edema by using predefined criteria . - pubmed
Three of the four patients who had stage 1 or 2 hepatic encephalopathy at the time of initial assessment ultimately had a good outcome . - pubmed
Of seven patients with stage 3 encephalopathy , two had rapid deterioration to brain death , three died of nonneurologic causes , and two had a good outcome after liver transplantation . - pubmed
One patient with stage 4 hepatic encephalopathy died , and autopsy showed cerebral edema . - pubmed
The clinical and radiologic signs of cerebral edema in patients who have progression to stage 3 hepatic encephalopathy can be reversed with conventional treatment of increased intracranial pressure . - pubmed
Whether early recognition and treatment of cerebral edema result in increased survival of patients with FHF remains to be determined . - pubmed
Selective in vivo antagonism of pinacidil - induced hypotension by the guanidine U37883A in anesthetized rats . - pubmed
Tumors in St. Lawrence beluga whales ( Delphinapterus leucas ) A population of 450 - 500 belugas ( Delphinapterus leucas ) resides in the polluted estuary of the St. Lawrence River . - pubmed
Overall , 28 of the 75 confirmed tumors reported so far in cetaceans ( 37 % ) were from this small population of beluga whales in the St. Lawrence Estuary . - pubmed
Between 1980 and 1990 , 25 patients were treated for large incisional hernias using the skin lacing technique . - pubmed
Correlation between function and structure in " epileptic " human hippocampal tissue maintained in vitro . - pubmed
In addition , we observed a distinctive early hemodynamic profile for patients with strep TSS that was unlike that for patients who had typical gram - negative septic shock ; this profile was consistent with toxic cardiomyopathy ( i.e. - pubmed
Herein we present the results of pudendal canal decompression ( PCD ) , performed for the treatment of FI in 21 patients whose CRP was corrected by Ivalon sponge rectopexy 5.2 years before presentation . - pubmed
Postoperatively , seven ( 53.8 % ) of the patients with partial FI showed full fecal control with normalization or improvement of the perianal hypoesthesia , rectal neck pressure , EMG of EAS and LA , as well as PNTML . - pubmed
We extracted massive disciform subretinal lesions in eight eyes of seven patients with age - related macular degeneration via pars plana access . - pubmed
The chronic administration of docosahexaenoic acid reduces the spatial cognitive deficit following transient forebrain ischemia in rats . - pubmed
The purpose of this study was to investigate whether chronic administration of docosahexaenoic acid is able to reduce spatial cognitive deficit following transient ischemia in rats . - pubmed
Rats were subjected to 10 min of transient forebrain ischemia by the method of four - vessel occlusion and were tested in a radial eight - arm maze task after cerebral reperfusion . - pubmed
A comprehensive evaluation of myelination during normal human development is essential to understand the pathology of congenital diseases of white matter . - pubmed
By contrast , alpha - phenyl - tert - butyl nitrone did not significantly reduce the drug - induced rotation asymmetry in rats with a 3 - nitropropionic acid lesion . - pubmed
The behavioural studies revealed that the combination of multiple lesions seen in 3 - nitropropionic acid - lesioned rats significantly exacerbated paw - reaching deficits and amphetamine - induced rotation asymmetry . - pubmed
The intrastriatal injection of 3 - nitropropionic acid led to degeneration of both intrinsic striatal neurons and the nigrostriatal dopaminergic system , suggesting that this lesion may provide an animal model of a form of multiple system atrophy rather than Huntington ' s disease . - pubmed
Mouse models will be powerful tools in the study of human PWS phenotype and imprinting mechanisms . - pubmed
One thousand one hundred and twenty - seven patients with vascular lesions were followed by the Department of Pediatric Oncology , Hacettepe University , for 19 years . - pubmed
The distribution of the vascular lesions was as follows : 969 patients had hemangiomas , 120 had lymphatic malformations , 18 had combined vascular malformations , 11 had venous malformations , six had port - wine stain , and three had angiokeratoma . - pubmed
METHODS : Patients ( 18 - 80 yr ) with a culture proven H. - pubmed
RESULTS : A total of 104 patients , 54 men , age 54+/-14 yr , ( 36 duodenal ulcer , 16 gastric ulcer , and 52 functional dyspepsia ) were included . - pubmed
The effect of manual lung hyperinflation and postural drainage on pulmonary complications in mechanically ventilated trauma patients . - pubmed
Three patients with advanced systemic sclerosis and recurrent or incessant monomorphic ventricular tachycardia underwent cardiac electrophysiologic studies . - pubmed
As expected for environmental isolates , all strains had a Lactococcus lactis subsp . - pubmed
Twenty - four patients ( 38 % ) had pancreatic disorders : acute pancreatitis ( n = 20 ) , chronic calcifying pancreatitis ( n = 2 ) , and pancreatic carcinoma ( n = 2 ) . - pubmed
The incidence of acute pancreatitis was significantly higher in patients with an abnormal pancreatogram , particularly dilatation , protein plugs or stones of the common channel or main pancreatic duct , and coexisting pancreatic ductal anomaly . - pubmed
All patients with choledochal cyst underwent cyst excision and hepaticojejunostomy . - pubmed
Eleven patients without choledochal cyst or pancreatobiliary carcinoma underwent cholecystectomy alone . - pubmed
No patients experienced pancreatitis during a mean postoperative follow - up of 6.7 years . - pubmed
The incidence of benign mesothelial cells in mediastinal lymph nodes in patients with a history of pericarditis or pleuritis is reported in this study . - pubmed
Alopecia areata - like hair loss in C3H / HeJ mice and DEBR rats can be reversed using topical diphencyprone . - pubmed
This study demonstrates the ability to treat successfully alopecia areata - like hair loss in both mouse and rat models using topical immunotherapy with diphencyprone . - pubmed
While intensive farming practices have been linked with the rise in foodborne illness in humans , it is interesting to note that the rise has continued even when there has been a shift to less intensive farm production systems . - pubmed
Thirty - two eyes of 16 consecutive patients who underwent trabeculectomy for uncontrolled glaucoma of various causes form the study group . - pubmed
The first contrast - enhanced images of 80 patients with 160 focal liver lesions ( hepatocellular carcinoma , n = 79 ; cavernous hemangioma , n = 51 ; metastatic tumor , n = 30 ) were then retrospectively reviewed . - pubmed
MATERIALS AND METHODS : Sixteen pre - eclamptic patients and 18 healthy pregnant women were studied . - pubmed
METHODS : This was a prospective randomized study of patients who received general surgery consultation for appendicitis . - pubmed
CLINICAL FINDINGS : A total of 271 patients with a variety of underlying malignancies received busulfan - containing myeloablative chemotherapy prior to aPBSCT ; none of these patients received total body irradiation . - pubmed
Ten individuals developed IPS , with a median time of onset of 102 days after stem cell infusion . - pubmed
Nine patients diagnosed with IPS were treated with high doses of glucocorticoids parenterally . - pubmed
Despite heroic measures , eight patients died of IPS . - pubmed
DISCUSSION : Chronic low - dose busulfan therapy results in lung injury in 4 - 6 % of patients after several years of treatment and once the cumulative dosage begins to approach 3 g. High - dose , short - course busulfan ( 16 mg / kg)-containing conditioning chemotherapy prior to aPBSCT can also be complicated by IPS . - pubmed
Mortality from this complication is 80 % , but some patients survive without long - term pulmonary sequelae following early treatment with glucocorticoids . - pubmed
- In 237 women ( mean age 62.9+/-7.4 years ) osteoporosis was defined by a T - score at the femoral neck below -2.5 SD . - pubmed
METHODS : Twenty adult sheep had AAAs surgically created by replacing a segment of the infrarenal aorta with an autologous jugular venous graft . - pubmed
Three months later , surviving animals underwent percutaneous implantation of macroporous polyester - covered nitinol stents ; 3 animals with untreated AAAs served as controls . - pubmed
RESULTS : Seven ( 35 % ) animals died within 24 hours of causes related to the technique ; 1 animal developed paraplegia and was sacrificed on day 1 . - pubmed
CLINICAL CASE : A 33 - year - old woman presented with seizures and a right parietotemporal syndrome of acute onset . - pubmed
In this study , the angle and its effect on flow velocity measurements were assessed with transcranial color Doppler sonography in patients with MCA stenosis . - pubmed
METHODS : Eighteen patients ( median age , 53 y ; age range , 22 - 72 y ) who satisfied qualifying criteria ( eg , angiographically revealed unilateral MCA stenosis of & gt ; or = 50 % ) were selected from 149 consecutive patients enrolled in a prospective study of transcranial color Doppler sonography and cerebral digital subtraction angiography . - pubmed
CONCLUSION : In patients with moderate or severe MCA stenosis , the angle of insonation can be substantial and cause large errors when flow velocities are measured without angle correction . - pubmed
During past decades , many attempts have been made to induce or enhance tumour - specific T - cell immunity in cancer patients by vaccination . - pubmed
The second patient recovered but developed hemiparesis . - pubmed
METHODS : VEP of 63 patients with nasopharyngeal carcinoma were tested before , at the end of , half a year , one year , 2 years and 3 years after their radiotherapy . - pubmed
In animals , GM1 ganglioside has been shown to reduce some of the behavioral deficits that follow Central Nervous System lesions . - pubmed
[ Study of a strain of Bacillus , pathogenic for certain insects , identifiable with Bacillus thuringiensis Berliner ] . - pubmed
Incidence of venous thromboembolism in patients undergoing craniotomy and motor mapping for glioma without intraoperative mechanical prophylaxis to the contralateral leg . - pubmed
OBJECT : Evidence - based reviews support the use of venous thromboembolism ( VTE ) prophylaxis in the form of compression devices and/or stockings for patients undergoing craniotomy . - pubmed
In patients undergoing craniotomy with motor mapping for glioma , the contralateral lower extremity should remain visible so that motor responses can be accurately identified . - pubmed
As a consequence , these patients could be placed at a higher risk to develop VTE . - pubmed
The authors have quantified the incidence of VTE in patients undergoing craniotomy with motor mapping and have shown that there is no increased risk of developing a VTE in the contralateral lower extremity when compression devices are not used . - pubmed
Intraoperative VTE prophylaxis in all patients consisted of ipsilateral ( that is , ipsilateral to the hemisphere being mapped ) lower - extremity mechanical prophylaxis ( antiembolism stocking plus compression device ) . - pubmed
Six patients ( 3.3 % ) experienced VTE . - pubmed
Two other patients ( 1.1 % ) only had PE . - pubmed
There were no deaths from thromboembolic complications and no statistically significant predisposition to VTE in the contralateral lower extremity among patients not receiving intraoperative prophylaxis . - pubmed
CONCLUSIONS : The incidence of VTE in patients undergoing craniotomy with motor mapping is comparable to that in patients receiving bilateral lower - extremity mechanical VTE prophylaxis . - pubmed
Furthermore , calvarial metastases are relatively uncommon in children compared to adults . - pubmed
The possibility of neuroblastoma presenting in this unique fashion and the importance of considering a chemosensitive tumor such as neuroblastoma in the differential diagnosis of a solitary calvarial mass in a child is highlighted by our report . - pubmed
PATIENTS : Forty patients ( 33 men and 7 women ) with moderate to severe traumatic brain injury ( mean age , 37 + /- 16 yrs ) were studied the day after termination of mechanical ventilation ( 7 - 60 days after trauma ) . - pubmed
MEASUREMENTS AND MAIN RESULTS : In traumatic brain injury patients , mean baseline and low - dose stimulation test - stimulated cortisol levels were 17.2 + /- 5.4 microg / dL and 24.0 + /- 6.6 microg / dL , respectively . - pubmed
CONCLUSIONS : Adrenal cortisol secretion after dynamic stimulation is deficient in a subset of critically ill patients with moderate to severe head injury . - pubmed
Our studies provide the first evidence that human nonsecretory myeloma may result from an alteration in the light - chain constant region . - pubmed
The goal of this study was to evaluate ARF in a large group of patients who received nonmyeloablative HCT . - pubmed
ARF ( & gt;50 % decrease in GFR ) occurred in 40.4 % of patients over a 3 - mo period , with 4.4 % of patients requiring dialysis . - pubmed
METHODS : Spherical ablations of -10.00 D were performed on 11 fresh porcine corneas using either the Technolas Keracor 217C scanning - spot or the Nidek EC-5000 scanning - slit beam excimer laser . - pubmed
The responses to manipulation of extracellular and intracellular calcium are altered in the streptozotocin - diabetic rat colon and ileum . - pubmed
Studies were performed to see if alterations in Ca2 + homeostasis underlie the gastrointestinal motility complications seen in many diabetic patients . - pubmed
Experiments were performed on colonic and ileal tissues taken from streptozotocin - induced diabetic and control rats . - pubmed
A gene(s ) for all - trans - retinoic acid - induced forelimb defects mapped and confirmed to murine chromosome 11 . - pubmed
All - trans - retinoic acid ( RA ) induces various anatomical limb dysmorphologies in mice dependent on the time of exposure . - pubmed
During early limb development , RA induces forelimb ectrodactyly ( digital absence ) with varying susceptibilities for different inbred mouse strains ; C57BL/6N are highly susceptible while SWV are resistant . - pubmed
The human syntenic region of this locus has been previously linked to Meckel syndrome ; the phenotype includes postaxial polydactyly , an ectopic digital defect hypothesized to be induced by a common molecular pathway with ectrodactyly . - pubmed
There are limited data regarding the antifungal susceptibility of yeast causing vulvovaginal candidiasis , since cultures are rarely performed . - pubmed
Susceptibility testing was performed on vaginal yeast isolates collected from January 1998 to March 2001 from 429 patients with suspected vulvovaginal candidiasis . - pubmed
Breast tumours were induced in female Sprague - Dawley rats by N - methyl - n - nitrosourea ( 50 mg kg(-1 ) , i.p ) . - pubmed
, was administered to the tumour bearing rats via the tail vein . - pubmed
The AUC(0 - infinity ) ( 9.42 + /- 3.18 microg h mL(-1 ) ) , clearance ( 0.69 + /- 0.17 L h(-1 ) kg(-1 ) ) , volume of distribution ( 10.31 + /- 4.54 L kg(-1 ) ) and half life ( 1.00 + /- 0.32 h ) of [ 3H ]- paclitaxel in tumour rats were similar in rats treated with IRL 1620 or vehicle . - pubmed
Tumour concentration of [ 3H ]- paclitaxel was determined in rats treated with IRL 1620 or vehicle and there was a significant increase in tumour paclitaxel concentration ( 308.59 + /- 24.42 % ) in rats treated with IRL 1620 compared with vehicle . - pubmed
Infectious bursal disease virus ( IBDV ) causes an immunosuppressive disease in chickens and leads to severe economic losses in the poultry industry . - pubmed
Phenserine also showed small , non dose - dependent effects on learning in studies in aged rats and lower toxicity than physostigmine . - pubmed
Gene expression profiling in human cardiovascular disease . - pubmed
Most of these studies have been successfully performed for human cancers . - pubmed
Inspired by these results , researchers in the cardiovascular field have also started using large - scale transcriptional analysis to better understand and classify human cardiovascular disease . - pubmed
Many individuals attempting to lose weight have hypertension , especially those with diabetes , and the prevalence of hyperaldosteronism among hypertensive patients is higher than previously recognized . - pubmed
We present a patient with Type 2 diabetes and previously undiagnosed hyperaldosteronism who developed life - threatening hypokalaemia while following a low - carbohydrate diet . - pubmed
CASE REPORT : A 60 - year - old man with diet - treated Type 2 diabetes and hypertension presented with generalized muscle weakness and serum potassium of 1.9 mmol / l. He had succeeded in losing three and a half stones during the previous 4 months by adhering strictly to a low - carbohydrate diet . - pubmed
The majority of these people are normokalaemic and remain undiagnosed . - pubmed
This technique is not known to have been described previously in the diagnostic investigation of r - PDA in dogs . - pubmed
METHODS : We classified 67 patients with PPA into three clinical variants : semantic dementia ( SEMD ) , progressive nonfluent aphasia ( PNFA ) , and logopenic progressive aphasia ( LPA ) , and we compared the severity of behavioral dysfunction , as measured by the Neuropsychiatric Inventory , in these groups and patients with frontotemporal dementia ( FTD ) and Alzheimer disease ( AD ) . - pubmed
Since cellular sensitivity of primary human fibroblasts usually reflects clinical sensitivity such patients with cancer would be at risk of increased toxicity . - pubmed
In group I , all treated animals were followed until death to assess therapeutic effect on survival . - pubmed
In recent decades , apple cider has been implicated in a series of outbreaks of foodborne illness . - pubmed
Twenty - seven patients with limited SSc ( ISSc ) without interstitial lung involvement were studied . - pubmed
Eighteen of 27 SSc patients presented an ex - PAP & gt ; 40 mmHg , while in 9 of 27 patients ex - PAP values remained & lt ; 40 mmHg ( 48.8 + /- 4.5 mmHg versus 36.2 + /- 3.1 mmHg ; P & lt ; 0.001 ) . - pubmed
Further mechanistic studies and randomized controlled clinical intervention trials with lycopene involving cancer patients are warranted . - pubmed
A prospective study of sentinel lymph node status and parametrial involvement in patients with small tumour volume cervical cancer . - pubmed
METHODS : After radical abdominal hysterectomy , 158 women patients were stratified into two groups based on tumour size : In Group 1 ( 91 women ) tumours were less than 20 mm and less than half of stromal invasion . - pubmed
In Group 2 ( 67 women ) tumours were between 20 and 30 mm and infiltration was not more than 2/3 of cervical stroma . - pubmed
Distraction plate fractures , screw loosening or absence of new bone formation were the complications encountered in the other three patients . - pubmed
Impact of the degree of liver resection on survival for patients with multiple liver metastases from colorectal cancer . - pubmed
RESULTS : As the patients undergoing major resection were more likely to have multiple ( p = 0.014 ) and large tumors ( p = 0.021 ) compared to the minor - resection patients , their overall survival was worse ( p = 0.046 ) and the disease - free rate tended to be poorer . - pubmed
When patients with six or more metastases were selected and analyzed , the overall survival of patients who had a major resection was significantly poorer than those who had minor resections ( p = 0.028 ) , although the clinical characteristics were comparable between the two groups . - pubmed
Twenty - eight nonobese women with previous severe preeclampsia and 20 women with a previous normotensive pregnancy were studied 5 to 6 years after the index pregnancy . - pubmed
METHODS : From January 2002 to May 2007 , 18 patients with old scaphoid fractures were treated by grafting bones from distal radius and fixing absorbable screws . - pubmed
INTRODUCTION : There is a lack of awareness of the prevalence of infection by Helicobacter pylori ( HP ) and its histopathological characterization in children in Peru . - pubmed
CONCLUSION : A high prevalence of infection by HP was found in children who underwent an upper endoscopy . - pubmed
In this pilot study , we first hypothesized levels of synovial fluid markers would be higher in patients with cartilage lesions than in patients with no cartilage lesions , and then we hypothesized the levels of synovial fluid markers would decrease after cartilage repair . - pubmed
Fifteen patients undergoing knee arthroscopy for various symptoms but with no apparent cartilage lesions served as control subjects . - pubmed
We detected reduced feed intake resulting in lower growth , weight gain and muscle protein accretion in salmon fed plant protein compared to a diet based on fish meal . - pubmed
Interactions of the autonomic nervous system with local immune cells play an important role in the development of IBD , and the balance of autonomic nerve function is broken in IBD patients with sympathetic overactivity . - pubmed
Lamina propria mononuclear cells ( LPMCs ) from mice with TNBS colitis were cultured in the absence or presence of RX821002 or UK14304 , and stimulated further by lipopolysaccharide . - pubmed
In future it may be possible to separate the genetic , enzymatic and environmental factors that are responsible for increased vulnerability of some individuals to alcohol abuse ( Fig . - pubmed
Peri- and postnatal developmental toxicity of salcaprozate sodium ( SNAC ) in Sprague - Dawley rats . - pubmed
In summary , SNAC administered orally at 1000 mg / kg / d to pregnant rats from gestation to weaning resulted in a slight decrease in maternal body weights ( -3.8 % ) and prolonged gestation , along with an increase in stillbirths , but had no effects on growth and development in surviving offspring . - pubmed
Although controversy remains regarding indications for testosterone supplementation in aging men due to lack of large - scale , long - term studies assessing the benefits and risks of testosterone - replacement therapy in men , reports indicate that TRT may produce a wide range of benefits for men with hypogonadism that include improvement in libido and sexual function , bone density , muscle mass , body composition , mood , erythropoiesis , cognition , quality of life and cardiovascular disease . - pubmed
The aim of our study was to assess the long - term safety and efficacy of MTX in patients with chronic severe forms of AA totalis . - pubmed
PATIENTS AND METHODS : Thirty - three patients ( 24 women and nine men ) with AA totalis or universalis were included . - pubmed
Relapse was observed on corticosteroid dose reduction or withdrawal in 16 of the 20 patients in whom total hair regrowth initially occurred . - pubmed
Regrowth after treatment of relapse was seen in 14 of these 16 patients ( 87 % ) . - pubmed
Seven patients experienced adverse events consisting of transient elevated transaminases ( n=4 ) , persistent nausea ( n=2 ) and lymphocytopenia ( n=1 ) . - pubmed
CONCLUSION : MTX alone or in combination with low doses of oral corticosteroids resulted in complete hair regrowth in about half of these patients presenting AA totalis or universalis . - pubmed
This study evaluated whether two people with multiple disabilities would be able to improve their pointing performance through an Automatic Target Acquisition Program ( ATAP ) and a newly developed mouse driver ( i.e. - pubmed
We aimed to detect the presence of HSV 1 and 2 ( herpes simplex virus ) and HHV8 ( human herpesvirus 8) in our patients who were suffering from pemphigus vulgaris . - pubmed
CONCLUSION : Inability to detect HHV8 and HSV DNA in this study suggests that herpesviruses may be only occasional factors for development or exacerbation of pemphigus vulgaris . - pubmed
Distal embolism is the most important complication for the patients with vulnerable plaque , which is detected by ultrasound sonography or MRI . - pubmed
Hyperperfusion may also occur in patients with impairment of the cerebrovascular reactivity , which is detected by single photon emission computed tomography ( SPECT ) with acetazolamide challenge . - pubmed
We should identify patients with high risk for CAS due to anatomy or vulnerability of the plaque to avoid periprocedural complication . - pubmed
Daily probiotic 's ( Lactobacillus casei Shirota ) reduction of infection incidence in athletes . - pubmed
A high proportion of participants with good response rates to topical treatment ( 58%-92 % ) experience local side effects such as itching and burning , less commonly erosion and ulceration , but the proportion of participants ceasing treatment has not been high . - pubmed
Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients . - pubmed
The goal of this study was to investigate the effects of natalizumab therapy on the immune cell composition and phenotype in the blood of relapsing MS patients treated over the course of 12 months . - pubmed
We collected peripheral blood from 26 RRMS patients before treatment onset , and then 6 and 12 months after therapy . - pubmed
These changes may help to explain both the mechanisms of action of natalizumab and also shed light on the potential for the observed increase in PML in these patients . - pubmed
METHODS : A total of 81 previously treated histopathologically proven glioma patients ; with clinical and conventional imaging findings suspicious of recurrence were included in this study . - pubmed
Data was censored , if the patient died of disease or at the end of the study . - pubmed
Effects of enoxaparin in the rat hippocampus following traumatic brain injury . - pubmed
Purpose of this study was to investigate the effects of low molecular weight heparin , enoxaparin , on different parameters of the hippocampal damage following traumatic brain injury ( TBI ) in the rat . - pubmed
Rats were sacrificed 48h after the induction of TBI . - pubmed
These findings demonstrate that enoxaparin may reduce oxidative damage , inflammation and astrocytosis following TBI in the rat and could be a candidate drug for neuroprotective treatment of this injury . - pubmed
Honeycombs , bees , honey and propolis from depopulated hives were analyzed for pesticide residues , whereas from active beehives only honey and propolis were evaluated . - pubmed
Interventional Radiology ( IR ) is occupying an increasingly prominent role in the care of patients with cancer , with involvement from initial diagnosis , right through to minimally invasive treatment of the malignancy and its complications . - pubmed
Therapeutic applications of IR in the oncology patient include local tumour treatments such as transarterial chemo - embolisation and radiofrequency ablation , as well as management of complications of malignancy such as pain , organ obstruction , and venous thrombosis . - pubmed
METHODS : Our cross - sectional study was carried out in 10 Italian rheumatology centers between January and September 2009 , and enrolled all consecutive patients with PsA and FM who agreed to participate . - pubmed
RESULTS : Two hundred sixty - six patients with PsA ( mean age 51.7 yrs ; disease duration 10.2 yrs ) and 120 patients with FM ( mean age 50.2 yrs ; disease duration 5.6 yrs ) were evaluated . - pubmed
Univariate analysis showed that patients with FM had higher mean tender point and enthesitis scores , more somatic symptoms , and responded less to NSAID . - pubmed
This research was carried out to investigate if zerumbone , a natural cyclic sesquiterpene isolated from Zingiber zerumbet Smith , will produce the anticancer effects on pancreatic carcinoma cell lines . - pubmed
Genome sequence of erythromelalgia - related poxvirus identifies it as an ectromelia virus strain . - pubmed
An epidemic form of this syndrome occurs in secondary students in rural China and a virus referred to as erythromelalgia - associated poxvirus ( ERPV ) was reported to have been recovered from throat swabs in 1987 . - pubmed
Studies performed at the time suggested that ERPV belongs to the orthopoxvirus genus and has similarities with ectromelia virus , the causative agent of mousepox . - pubmed
We have determined the complete genome sequence of ERPV and demonstrated that it has 99.8 % identity to the Naval strain of ectromelia virus and a slighly lower identity to the Moscow strain . - pubmed
Small DNA deletions in the Naval genome that are absent from ERPV may suggest that the sequenced strain of Naval was not the immediate progenitor of ERPV . - pubmed
MATERIALS AND METHODS : Between January 2006 and December 2009 a functional assessment of 15 patients ( 10 males and 5 females ) who had undergone ankle arthrodesis for posttraumatic arthritis and/or avascular necrosis ( AVN ) talus ( n=6 ) , malunited bimalleolar fracture ( n=4 ) , distal tibial plafond fractures ( n=3 ) , medial malleoli nonunion ( n=2 ) . - pubmed
RESULTS : All patients had sound ankylosis and no complications related to the surgery . - pubmed
CONCLUSION : Spectral domain OCT is a valuable imaging technology enabling detailed visualization of retinal changes in patients with CSC . - pubmed
Hemodialysis does not affect everolimus pharmacokinetics : two cases of patients with metastatic renal cell cancer . - pubmed
Assessment of cerebrovascular reactivity using real - time BOLD fMRI in children with moyamoya disease : a pilot study . - pubmed
PURPOSE : This pilot study aims to test the reliability and clinical validity of the assessment of cerebrovascular reactivity ( CVR ) with real - time blood - oxygen - level - dependent ( BOLD ) fMRI ( rtCVR ) in comparison with standard off - line processing in children with moyamoya disease . - pubmed
CONCLUSIONS : rtCVR assessment in children with moyamoya disease is feasible , and the results are comparable to that of standard off - line analysis . - pubmed
METHODS : We reviewed the literature dealing with altered mental status or seizures in enuretic subjects on desmopressin . - pubmed
The retained publications included patients who were described individually , revealing data on mode of administration , further identifiable factors predisposing to hyponatremia , presentation and clinical course . - pubmed
We developed an F1 mouse host embryo ( Perfect Host , PH ) that selectively ablates its own germ cells via tissue - specific induction of diphtheria toxin . - pubmed
Neurological disease in lambs associated with exposure to high environmental temperature and humidity . - pubmed
BACKGROUND : We detected a pattern of lambs presenting with hyperthermia and neurological signs during the summer . - pubmed
ANIMALS : Fifteen clinical cases of lambs less than 12 months of age presenting with neurological signs , tachypnea , and hyperthermia over 4 summers . - pubmed
Medical records were searched for lambs less than 12 months of age that presented with neurological signs including the following : kyphosis , pelvic limb hyperextension , treading of feet , muscle tremors and recumbency , and hyperthermia of greater than 104 F. A grading system was established to describe severity of presenting neurological signs . - pubmed
Eighteen female patients with a diagnosis of BPD and 18 healthy control subjects anticipated cued visual stimuli with prior known emotional valence or prior unknown emotional content during functional magnetic resonance imaging . - pubmed
DESIGN : Seventy - nine ( 79 ) children , aged 8 - 16 years , were studied and divided into four groups : 19 control ( BMI z - score range -2.15 - 1.24 ) , 20 overweight ( 1.34 - 2.49 ) , 20 obese ( 2.50 - 2.87 ) and 20 ultra - obese ( 3 - 4.37 ) . - pubmed
In patients with congenital heart disease , cardiac MRI is established as a valuable diagnostic tool in daily clinical management , especially for the evaluation of pulmonary valve defects . - pubmed
METHODS AND RESULTS : Excluding medication used in atrial fibrillation , we matched individuals on ACEi monotherapy 1:1 with individuals on beta - blocker ( n = 48 658 ) , diuretic ( n = 69 630 ) , calcium - antagonist ( n = 57 646 ) , and ARB monotherapy ( n = 20 158 ) . - pubmed
Identification and validation of novel candidate protein biomarkers for the detection of human gastric cancer . - pubmed
By combining a validated preclinical mouse model with a proteomic approach we have recently discovered novel biomarkers for the detection of gastric cancer . - pubmed
Eighty patients with isolated SVT of the legs were instructed to wear compression stockings ( 23 - 32 mmHg ) ( CG ) or no compression ( NCG ) for 3 weeks . - pubmed
At day 7 , patients in the CG revealed a significantly faster thrombus regression ( p = .02 ) . - pubmed
Aprocta cylindrica ( Nematoda ) infection in a European Robin ( Erithacus rubecula ) in Britain . - pubmed
A European Robin ( Erithacus rubecula ) found dead in England had marked blepharitis and periocular alopecia associated with Aprocta cylindrica ( Nematoda : Aproctidae ) and concurrent mixed fungal infections . - pubmed
Aprocta cylindrica should be considered a differential diagnosis in periocular abnormalities of robins and other insectivorous , migratory passerines in Western Europe . - pubmed
Serum galactomannan - based early detection of invasive aspergillosis in hematology patients receiving effective antimold prophylaxis . - pubmed
BACKGROUND : There is a practical need to investigate the performance of the serum galactomannan ( GM ) assay in hematology patients with a potentially low pretest risk of invasive aspergillosis following effective antimold prophylaxis . - pubmed
METHODS : We measured frailty ( shrinking , weakness , exhaustion , low physical activity , and slowed walking speed ) , other patient and donor characteristics , longitudinal MMF doses , and graft loss in 525 kidney transplantation recipients . - pubmed
To address this , the responses of two strains of the model brown alga Ectocarpus siliculosus isolated from sites with different histories of metal contamination exposed to total copper ( CuT ) concentrations ranging between 0 and 2.4 muM for 10 days were investigated . - pubmed
parvum ( odds ratio [ OR ] = 2.6 ; 95 % confidence interval [ CI ] , 1.3 - 5.6 ; P = 0.02 ) , BRV ( OR = 2.7 ; 95 % CI , 1.3 - 5.9 ; P = 0.01 ) and co - infection with more than one agent ( compared with mono - infection : OR = 2.5 ; 95 % CI , 1.3 - 4.8 ; P = 0.01 ) were associated with increased odds of liquid faeces in calves which were 9 to 21 days old . - pubmed
Vaccinating cows against calf enteropathogens ( OR = 0.2 ; 95 % CI , 0.1 - 0.9 ; P = 0.03 ) , administering waste milk ( from mastitis and/or containing antibiotics ; OR = 0.4 ; 95 % CI , 0.1 - 0.8 ; P = 0.01 ) , the sex of calves ( females compared to males OR = 0.2 , 95 % CI , 0.07 - 0.7 ; P & lt;0.01 ) , and the use of straw for bedding ( OR = 0.2 ; 95 % CI , 0.03 - 0.9 ; P = 0.03 ) decreased the odds of liquid faeces . - pubmed
METHODS : In vivo studies , 50 mul PBS or 1.5x10(6)(Norm)BMSCs , ( GFP)BMSCs or ( CREG)BMSCs were implanted intramyocardially in myocardial infarction rat models . - pubmed
BACKGROUND : In patients with degenerative meniscal tears , subclinical cartilage degeneration may be present even if gross morphological changes are not evident . - pubmed
The aim of this study was to detect occult cartilage degeneration using T1rho MRI mapping in patients with meniscal tears without obvious radiographic osteoarthritis ( OA ) . - pubmed
Measuring glomerular filtration rate by iohexol clearance on filter paper is feasible in adolescents with type 1 diabetes in the ambulatory setting . - pubmed
Testing 24 women with androgenetic alopecia has demonstrated a positive effect of mesotherapy on the hair growth , hair thickness , with only insignificant increase of hair density . - pubmed
This randomized , double - blind controlled study evaluated the effects of a single 100 - mg oral dose of ABT-639 , compared with placebo , on abnormal spontaneous activity in peripheral C - nociceptors , measured for the first time by microneurography in adult patients with painful diabetic neuropathy . - pubmed
The utilization of microneurography as a means to measure abnormal activity in C - nociceptors in human clinical studies opens new possibilities for future studies of compounds targeting peripheral nerve hyperexcitability . - pubmed
Duck virus enteritis , also known as duck plague , is an acute herpes viral infection of ducks caused by duck enteritis virus ( DEV ) . - pubmed
The method of repeated immunization with a live attenuated vaccine has been used for the prevention and control of duck enteritis virus ( DEV ) . - pubmed
We thus propose an emotional model of ASD that adapts a Bayesian model of the uncanny valley effect , which holds that a human - looking robot can provoke repulsion and sensations of eeriness . - pubmed
Consequently , individuals with ASD may find it more comfortable , and may modify their emotional response , if the robots look like deformed humans , even if they appear " creepy " to typical individuals . - pubmed
Therefore , we suggest that our model explains the effects of robot - assisted therapy in children with ASD and that human - looking robots may have potential advantages for improving social interactions in ASD . - pubmed
The aims of this study is to compare the growth and glucose metabolism of three Lactobacillus reuteri strains ( i.e. - pubmed
It was also shown that , in the context of obtaining a large amount of biomass , DSM 20016 and DSM 17938 strains were the most effective in terms of growth kinetics . - pubmed
MATERIALS AND METHODS : We identified 422 patients who met National Comprehensive Cancer Network very low ( 199 ) and low risk ( 223 ) prostate cancer definitions who instead underwent radical prostatectomy . - pubmed
Prolonged Support Using a Percutaneous OxyRVAD in a Patient with End - Stage Lung Disease , Pulmonary Hypertension , and Right Cardiac Failure . - pubmed
Options for cardiopulmonary support in patients with severe pulmonary hypertension ( PH ) that is not associated with left - sided heart failure are limited . - pubmed
We describe the novel use of prolonged percutaneous venovenous extracorporeal membrane oxygenation as a right ventricular assist device in a patient presenting with cardiogenic shock because of severe PH decompensation . - pubmed
METHODS : The medical records of patients with ovarian CCC who had undergone primary staging surgery or cytoreductive surgery followed by systemic chemotherapy were retrospectively reviewed . - pubmed
Using a more clinically relevant sample , we extracted and amplified Plasmodium falciparum DNA from malaria - infected human blood cultures . - pubmed
Approximately half of patients with coronary spastic angina had pathologic exercise tests . - pubmed
Organic stenosis ( & gt;75 % ) was observed in 44 patients . - pubmed
Multiple spasms were recognized in 204 patients ( 68 % ) . - pubmed
Positive response was significantly higher in patients with organic stenosis than those without fixed stenosis ( 63.6 % vs. 33.2 % , p<0.001 ) . - pubmed
Moreover , ST elevation was more frequent in patients with organic stenosis than those without fixed stenosis ( 27.3 % vs. 1.2 % , p<0.001 ) . - pubmed
Positive response in patients with effort angina ( 46.8 % ) was higher than those in patients with rest angina ( 33.6 % ) and rest and effort angina ( 36.6 % ) , but not significant . - pubmed
CONCLUSIONS : TET was useful in documenting ischemia in patients with CSA . - pubmed
Moreover , we obtained the pathologic TET response in approximately half of patients with CSA . - pubmed
Pulmonary Embolism in a 3 - Year - Old Boy with Nephrotic Syndrome . - pubmed
We present the case of a 3 - year - old boy with nephrotic syndrome with mild respiratory symptoms who was shown by ventilation - perfusion scan to have pulmonary embolism . - pubmed
Onychomycosis caused by Aspergillus terreus . - pubmed
Between 1993 and 2011 , 107 patients with intracranial meningiomas involving MVS underwent surgery in our institution . - pubmed
Interestingly , there was no progression in patients that underwent radiation therapy or gamma knife radiosurgery for residual tumor . - pubmed
Overall , 5.2 % of urine isolates were ESBL and 9.5 % isolates with pyuria ( & gt;100x106 WC / L ) had ESBL , whereas only 22/1032 ( 2.1 % ) with no pyuria , ( P<0.0001 ) . - pubmed
It has formed the basis for the setting up of leg ulcer clinics in the community , the principles of patient assessment , and the use of four - layer bandages as the first - line treatment for patients with venous and mixed disease . - pubmed
This study sought to evaluate differences in nocturnal wakefulness in depressed individuals who did and did not have an antisuicidal response to ketamine . - pubmed
Vaccination of alpacas against Rift Valley fever virus : Safety , immunogenicity and pathogenicity of MP-12 vaccine . - pubmed
Previous outbreaks attributed camelids a significant role in the epidemiology of Rift Valley fever virus ( RVFV ) , making them an important target species for vaccination . - pubmed
Viral replication was confirmed by detection of various RVFV - antigens in hepatocytes by immunohistochemistry and the presence of mild multifocal necrotizing hepatitis . - pubmed
OBJECTIVE : To identify the predictors of RCD , in a population of community - dwelling patients with recently diagnosed late onset AD . - pubmed
All patients underwent a standardized clinical dementia investigation . - pubmed
Lymph Drainage During Wound Healing in a Hindlimb Lymphedema Mouse Model . - pubmed
CONCLUSIONS : In a hindlimb lymphedema mouse model , lymph transiently accumulated in subcutaneous tissue , and then was gradually absorbed by the existing lymph vessels . - pubmed
Among the various enteric diseases , necrotic enteritis ( NE ) is an enterotoxemic disease caused by Clostridium perfringens , which can result in severe economic losses in poultry farming . - pubmed
Bacillus subtilis PB6 was reported to prevent necrotic enteritis and improve performance in birds . - pubmed
Bacillus subtilis PB6 significantly ( P & lt ; 0.05 ) improved body weight and FCR ( 8 points ) compared to the control . - pubmed
A total of 145 PsA patients were included in the study . - pubmed
Nine patients ( 6.2 % ) reported the onset of mild infections resolved with antimicrobial specific oral regimen without therapy interruption . - pubmed
Treatment - related mortality ( TRM ) remains elevated in adult patients undergoing umbilical cord blood transplantation ( UCBT ) , including an early rise in TRM suggestive of excessive toxicity associated with the standard myeloablative total body irradiation ( TBI ) , fludarabine , and cyclophosphamide regimen . - pubmed
Thirty - one adult patients ( median age , 46 years ; range , 19 to 65 ) with hematologic malignancies ( acute leukemia / myelodysplastic syndrome , 77 % ; lymphoid malignancy , 23 % ) underwent single ( n = 1 ) or double ( n = 30 ) UCBT from 2010 to 2015 at our institution . - pubmed
The overall incidence of chronic GVHD at 2 years was 40 % ( 95 % CI , 22 % to 57 % ) , with 17 % of patients ( 95 % CI , 6 % to 33 % ) experiencing moderate to severe chronic GVHD by 2 years . - pubmed
The fungal strains were identified and registered at NCBI as Aspergillus niger asemoA ( KY473958.1 ) , Talaromyces purpurogenus asemoF ( KY488463.1 ) , Trichoderma harzianum asemoJ ( KY488466.1 ) and Aspergillus flavus asemoM ( KY488467.1 ) . - pubmed
BACKGROUND : The resistance of some medico - veterinary parasite strains as well as the unavailability and toxicity of synthetic anthelminthics on humans , animals and the impacts of their residues in the environment have pushed scientists to turn to plants with anthelminthic properties . - pubmed
Patients supported by LVADs were more likely to be supported longer ( p = 0.003 ) , have a higher death by cardiac event ( p = 0.013 ) and retransplantation rate ( p = 0.015 ) . - pubmed
Anti - tumor effects of the American cockroach , Periplaneta americana . - pubmed
Since the incidence of cancer has been on the rise due to increasing exposure to various carcinogenic factors in recent years , cancer has gradually become the first killer to the health of human beings . - pubmed
In this review , the research progress on the anti - tumor effects of P. - pubmed
This review aims to provide an overview of the research on anti - tumor effects of P. - pubmed
Many strains of zebrafish ( Danio rerio ) are readily available . - pubmed
The latter finding adds to the growing database of phenotypical differences between zebrafish of the AB and TL strain . - pubmed
Methods : Ninety - two patients with stage III NSCLC were analyzed retrospectively based on treatment given . - pubmed
Conclusions : Patients with stage IIIA and , perhaps IIIB NSCLC with a high performance status should be considered for trimodality treatment . - pubmed
The aim of the present study was to investigate the effects of carboxymethyl cellulose ( CMC ) and chitosan ( CH ) coatings containing Mentha spicata essential oil ( MSO 0.1 and 0.2 % ) on survival of Listeria monocytogenes , and physicochemical ( weight loss , titratable acidity and pH ) , microbial ( total viable count , psychrotrophic bacteria as well as yeasts and molds ) and sensory ( appearance , color , texture and overall acceptability ) properties of fresh strawberries during refrigerated storage . - pubmed
MATERIALS AND METHODS : Fifty - three patients with advanced lower rectal cancer were examined before and after neoadjuvant chemoradiotherapy with use of TRUS plus UE and CEUS and were diagnosed as having T stage disease . - pubmed
RESULTS : For patients with rectal cancer , ultrasonic T stages were lower after neoadjuvant chemoradiotherapy than before , with a statistically significant difference ( P & lt ; 0.05 ) . - pubmed
A battery of toxicological studies was conducted in accordance with international guidelines to investigate the genotoxicity and repeated - dose oral toxicity in rats of synthetic curcumin ( VEAMIN 99 , & gt;99 % purity ) . - pubmed
There was no evidence of mutagenicity in a bacterial reverse mutation test , whereas an in vitro mammalian chromosomal aberration test was positive for induction of chromosomal aberrations which is in line with results reported for natural curcumin . - pubmed
There was no evidence of genotoxicity in an in vivo mammalian micronucleus test . - pubmed
Association of tibial plateau leveling osteotomy with proximal tibial osteosarcoma in dogs . - pubmed
OBJECTIVE To assess for any association between a history of tibial plateau leveling osteotomy ( TPLO ) and subsequent development of proximal tibial osteosarcoma in dogs . - pubmed
ANIMALS 34 client - owned dogs in which proximal tibial osteosarcoma was diagnosed between January 2005 and December 2012 ( cases ) and 79 dogs without osteosarcoma , matched 3:1 to cases ( when possible ) by age , breed , and initial examination date ( controls ) . - pubmed
A multivariable conditional logistic regression model was constructed to evaluate associations of body weight and history of TPLO with the outcome of proximal tibial osteosarcoma in dogs . - pubmed
RESULTS After adjusting for body weight in the multivariable model , dogs with a history of TPLO were 40 times as likely to develop proximal tibial osteosarcoma as were dogs with no history of TPLO . - pubmed
CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that dogs with a history of TPLO were at increased risk of developing osteosarcoma of the proximal region of the tibia relative to dogs with no such history . - pubmed
Therefore , it is important for proximal tibial osteosarcoma to be included among the differential diagnoses for new or worsening hind limb lameness in dogs that underwent TPLO & gt;= 1 year previously . - pubmed
This phenomenon can also be observed in mycobacterial and fungal infections that produce granulomas in infected patients . - pubmed
Patients are often diagnosed with fractures , dislocations , bursitis , and muscle strain . - pubmed
To enhance its efficacy , a combinational study of selenium yeast ( SY ) and fish oil ( FO ) was performed in A549 , CL1 - 0 , H1299 , HCC827 lung adenocarcinoma ( LADC ) cells to investigate the enhancement in apoptosis induction and underlying mechanism . - pubmed
The primary efficacy endpoint was to demonstrate the superiority and higher accuracy of FD - OCT compared to 2D - QCA in evaluating stenosis severity in patients with ICL . - pubmed
Methods : A cohort of patients suffering from GCTTS of the hand and treated surgically were studied in terms of diagnosis , therapy , recurrence , as well as in terms of functional outcome with the use of the QuickDASH score . - pubmed
Prognosis and risk stratification in patients with decompensated heart failure receiving inotropic therapy . - pubmed
Methods : We analysed a prospective cohort of adult patients admitted with decompensated HF and ejection fraction ( left ventricular ejection fraction ( LVEF ) ) less than 50 % . - pubmed
Main aetiologies were dilated cardiomyopathy in 273 ( 37.0 % ) patients , ischaemic heart disease in 195 ( 26.5 % ) patients and Chagas disease in 163 ( 22.1 % ) patients . - pubmed
PURPOSE : To describe the clinical and histopathologic features secondary to ocular and periocular snakebites in dogs requiring enucleation . - pubmed
METHODS : Retrospective review of patients with recorded snakebite envenomation from the archives of the Comparative Ocular Pathology Laboratory of Wisconsin ( COPLOW ) and Texas A&M Veterinary Medical Teaching Hospital ( 1997 - 2017 ) . - pubmed
The cases included in this study required witnessed snakebites to the dog by the owner , clinical signs supportive of periocular or ocular envenomation , and/or histopathologic lesions compatible with snakebites . - pubmed
As in humans and horses , studying inflammation of the deep airways by lung cytology raises the possibility of preventing respiratory disease and targeting its treatment in the future . - pubmed
Mean BALf neutrophil percentage was 36.6 % ( SD 23.8 ; R 0 - 97.4 ) and only a positive induced tracheal cough reflex ( P = 0.04 ) , standing posture ( P = 0.03 ) increased breathing rate ( P = 0.02 ) and isolation of Pasteurella multocida ( P = 0.005 ) , were associated with increased neutrophil percentage . - pubmed
PURPOSE : As a conserved cellular stress response , autophagy has recently been demonstrated to be involved in the pathogenesis of several human cancers . - pubmed
METHODS : A total of 83 patients with primary HCC were enrolled in this study . - pubmed
In this review , we discuss the burden of bleeding in anticoagulated patients and the need for reversal agents , review the mechanism of action of andexanet and critically evaluate the evidence for its efficacy and safety . - pubmed
Breast cancer is one of the most human malignant diseases and the leading cause of cancer - related death in the world . - pubmed
Based on these results , we can conclude that this immune score may be a useful tool for overall survival prediction and treatment guidance for patients with breast cancer . - pubmed
Impact of adjuvant therapy in patients with invasive intraductal papillary mucinous neoplasms of the pancreas . - pubmed
BACKGROUND : There is limited data on the efficacy of adjuvant therapy ( AT ) in patients with invasive intraductal papillary mucinous neoplasms of the pancreas ( IPMN ) . - pubmed
This single center retrospective cohort study aims to assess the impact of AT on survival in these patients . - pubmed
METHODS : Patients undergoing surgery for invasive IPMN between 1993 and 2018 were included in the study . - pubmed
Patients in the AT group were significantly younger , presented at higher T and N stages and had more perineural and lymphovascular invasion . - pubmed
N0 patients have excellent survival , and AT should probably be avoided in them , whereas it may be considered in patients with N+ disease . - pubmed
Sulfated vizantin showed no cytotoxicity against the human gingival cell line Ca9 - 22 . - pubmed
PARTICIPANTS : Patients diagnosed with acute ischemic stroke , January 1 , 2011 - May 31 , 2017 . - pubmed
PARTICIPANTS : A total of 71 934 post-9/11 Veterans with mTBI from the Chronic Effects of Neurotrauma Consortium Epidemiology warfighter cohort . - pubmed
Method Sample consisted of 59 tinnitus patients who reported stable tinnitus . - pubmed
BACKGROUND : Survival rates in patients with esophageal cancer undergoing esophagectomy have improved , but the prevalence of gastric tube cancer ( GTC ) has also increased . - pubmed
Total resection of the gastric tube with lymph node dissection is considered a radical treatment , but GTC surgery is more invasive and involves a higher risk of severe complications or death , particularly in elderly patients . - pubmed
CASE SUMMARY : We report an elderly patient with early GTC that had invaded the duodenum who was successfully treated with resection of the distal gastric tube and Roux - en - Y ( R - Y ) reconstruction . - pubmed
A 47 - year - old woman was diagnosed with PSC . - pubmed
ICH and normal specimens were obtained from the tissue adjacent to and distant from hematoma of ICH patients , respectively . - pubmed
There were under observation 440 patients with ischemic heart disease due to atherosclerosis of the coronary arteries in the phase of exacerbation of the disease and 52 patients suffering from hypertensive disease with a clinical picture of ischemic heart disease ; 192 practically healthy individuals were examined as controls . - pubmed
Significant increase in the levels of cholesterol , triglycerides , and glucose in blood of the patients with ischemic heart disease and of those with hypertensive disease was revealed . - pubmed
In patients with ischemic heart disease marked by pain and disorders of the rhythm as well as in individuals with hypertensive disease hormonal - metabolic shifts , monotypical in character , were noted . - pubmed
Utilizing antibarbiturate serum in an indirect immunofluorescence system , phenobarbital has been detected in the central nervous system of mice given an overdose of drugs . - pubmed
The use of non - human primates for production of antisera to human tumor - associated antigens . - pubmed
High - titered antisera against human melanoma- and leukemia - associated antigens have been produced in non - human primates . - pubmed
The data from this and from other studies suggest that this model may prove a valuable source of highly specific antisera against a variety of human tumor - associated antigens or alloantigens . - pubmed
In male mice and rats , one drop of an extract from Dryopteris filix mas , administered orally pure or suspended in sunflower - seed oil , caused a spectacular enlargement of the penis . - pubmed
From these observations and a review of the pertinent literature , we conclude that the patients described in this report have an organic deficiency of brain function , determined congenitally or in the early postnatal period . - pubmed
This article reports on the treatment of 21 obesity patients employing auricular acupuncture . - pubmed
It seems probable that the blood of goslings has a smaller oxygen carrying capability that that of the chicken and this might be reflected with their slower metabolic rate per body weight unit . - pubmed
Cryopreserved autologous platelet transfusions in alloimmunized patients with acute leukemia . - pubmed
Autologous platelets of 5 alloimmunized patients with acute leukemia in remission were cryopreserved with 5 % dimethylsulfoxide in liquid nitrogen and retransfused in the following therapy - induced thrombocytopenic phase . - pubmed
To evaluate the spectrum of coronary artery disease ( CAD ) in cocaine users , coronary angiograms obtained from 33 patients ( 26 men [ 79 % ] and 7 women [ 21 % ] , mean age 37 years ) with history of cocaine use and cardiac symptoms were retrospectively reviewed . - pubmed
Thirteen patients ( 40 % ) had normal coronary angiograms , and 20 ( 60 % ) had CAD ; 7 ( 21 % ) had mild CAD ( less than or equal to 70 % diameter stenosis ) , and 13 ( 40 % ) had significant CAD ( greater than 70 % diameter stenosis ) . - pubmed
Of 13 patients with significant CAD , 7 had 1 - vessel , 4 had 2 - vessel and 2 had 3 - vessel CAD . - pubmed
There was enzymatic evidence of myocardial infarction in 12 of 33 patients ( 36 % ) ; all 12 had CAD ( 10 with significant and 2 with mild CAD ) . - pubmed
Mean age and number of risk factors ( serum total cholesterol , cigarette smoking , systemic hypertension , diabetes mellitus , family history of CAD , and obesity ) in patients with CAD ( mild or significant ) and with normal coronary angiograms were not statistically different . - pubmed
All patients with CAD and low ejection fractions ( n = 12 ) had regional wall motion abnormalities , whereas all those with normal coronary arteries and low ejection fraction ( n = 6 ) had global hypokinesia . - pubmed
The correction of ARF was achieved in 85 % of the patients with a mask of O2 less than 40 % . - pubmed
The results suggest that NMR imaging is effective for assessing the results of initial palliative surgery for hypoplastic left heart syndrome , which seems to be important for managing patients before subsequent definitive surgery . - pubmed
In human atherosclerotic lesions , many of the macrophage foam cells also contain ceroid , an insoluble polymer formed by oxidation of mixtures of lipid and protein . - pubmed
In this study , the diagnostic value of a new tracer : 99mTc - methoxy - isobutyl - isonitrile ( MIBI ) has been demonstrated in patients with leg claudication . - pubmed
We successively performed muscle perfusion scans in 6 normals and 18 patients with claudication pain during rest and after exercise on the same day . - pubmed
Muscle perfusion abnormalities in all patients were consistent with the defects in the arteries of the affected limbs . - pubmed
Propofol in combination with fentanyl diminished mean arterial pressure ( -28.7 % ) and heart rate ( -17.3 % ) when used for induction in patients with ischemic heart disease , even in low doses and with slow administration . - pubmed
There was no evidence of non - homogeneous tissue perfusion as assessed by increases in lactate concentration , cardiac ischemia , or liver dysfunction in any of the patients . - pubmed
There were no postoperative complications in either group , but the return of consciousness , adequate spontaneous ventilation , and psychomotor activity was more rapid in the propofol patients . - pubmed
However , the use of propofolfentanyl for induction of anesthesia in patients with limited coronary perfusion is not recommended because of its hypotensive effect . - pubmed
In the present study we compared the binding characteristics of peripheral benzodiazepine - binding sites in human epithelial ovarian carcinoma with those in benign ovarian tumours and normal ovaries . - pubmed
Patients who were thought to be at high risk for postoperative ileus had a Foley catheter inserted intraoperatively through the greater curvature of the stomach . - pubmed
The procedure was found to be technically easy , well tolerated by the patients , and clinically useful , since postsurgical ileus was prevented or treated without the local and respiratory ill effects of the commonly used nasogastric tube . - pubmed
Toxicity of FK-506 in human fetal pancreas . - pubmed
Our results suggest that further work with FK will show that this immunosuppressive agent can be used with HFP transplantation into diabetic patients without toxicity to HFP . - pubmed
Using a lead exposure model considered to represent subclinical lead toxicity in man , it was shown that perinatal lead exposure disrupts opioid but not non - opioid mediated stress antinociception . - pubmed
As reported previously , the peculiar intracytoplasmic eosinophilic inclusion bodies ( IEIBs ) extensively appeared in the autopsied brain tissue from a 49 - year - old man having familial ataxia with cerebrospinal fluid abnormality , and histochemically showed abundant proteins , but few lipids and carbohydrates . - pubmed
Cauliflower growths in ulcers of leprosy -- a question of malignancy . - pubmed
Systemic activation of the coagulation mechanism is known to exist in patients with colon cancer . - pubmed
N -( 2 - hydroxypropyl ) methacrylamide polymeric prodrugs containing adriamycin bound to polymers via glycylphenylalanylleucylglycine side chains and , in one case , galactosamine bound via the same sequence , were tested for immunogenicity after intravenous , subcutaneous and oral application in two inbred strains of mice . - pubmed
Achieving oral health in patients with renal failure and renal transplants . - pubmed
The protocols for oral evaluation and treatment of patients with renal failure and renal transplants are presented . - pubmed
Local cerebral metabolic rate for glucose ( LCMRglc ) was measured with positron emission tomography using the 18F - fluorodeoxy - glucose method in five patients with chorea due to different underlying diseases . - pubmed
Hypometabolism was observed in the striatum bilaterally in patients with Huntington ' s disease , choreoacanthocytosis , sporadic progressive chorea and dementia , and pseudo - Huntington form of dentato - rubro - pallido - luysian atrophy ( DRPLA ) . - pubmed
The patient with hemichorea showed hypometabolism in the striatum on the contralateral side to the chorea . - pubmed
The patient with pseudo - Huntington form of DRPLA showed a diffusely decreased LCMRglc in other structures including the cerebral cortex , thalamus and cerebellum . - pubmed
These findings indicated that dysfunction of the striatum is relevant to the genesis of chorea in all these patients , even though the extent of dysfunction in other structures is different in each case . - pubmed
Somatosensory - evoked potential study in headache patients . - pubmed
Somatosensory - evoked potentials ( SEPs ) after median nerve stimulation were studied in 34 patients with common migraine , in 30 patients with muscle - contraction headache , and in 10 cluster headache patients . - pubmed
No changes were observed in muscle - contraction headache patients either with or without histamine administration . - pubmed
In these 10 patients , 9 were hypertensive , and the signs characteristics of parenchymal hemorrhage , e.g. - pubmed
Seven patients with non advanced cancer of the lower third of the rectum underwent sphincter - saving resection through a combined abdominoperineal approach . - pubmed
The mean follow - up is 8 months and all patients are free of recurrence and continent . - pubmed
A total of 433 extracorporeal lithotripsy procedures was performed for renal , ureteral and bladder stones by means of a system of ultrasonographic detection and piezoelectric destruction in 386 patients . - pubmed
Of the 217 patients with a renal stone reviewed at 3 months 161 ( 74 per cent ) had successful results and 56 ( 26 per cent ) failed therapy . - pubmed
The morbidity was low : 2 per cent of the patients suffered ureteral obstruction , 1.5 per cent had subcapsular hematoma and 4 per cent had fever . - pubmed
The use of sublingual nifedipine in a patient with a clonidine overdose . - pubmed
The sensitivity to lipolytic agents is altered in diabetic vs. control animals . - pubmed
Rats , rendered diabetic by STZ ( 65 mg / kg ) , were used on day 3 . - pubmed
Aluminum - associated osteomalacia and transfusion - induced hemosiderosis developed in an anephric patient receiving long - term maintenance treatment with continuous ambulatory peritoneal dialysis . - pubmed
We have used groin flaps to cover deep hand burn defects in nine patients . - pubmed
A series of nitroheterocyclic compounds with antimicrobial and radiosensitizing properties was tested for embryotoxicity in cultured Sprague - Dawley rat embryos , and their effects were compared with various other five - membered heterocycles . - pubmed
The dermatitis of 9 of the patients had flared after open oral challenge with balsam of Peru , and the dermatitis of 31 patients had flared after double - blind oral challenge . - pubmed
The AoE index ( AoE corrected for body surface area ) in patients with ASD was significantly greater than in disease - free subjects ( 0.81 vs 0.59 cm , p less than 0.01 ) . - pubmed
[ Vitamin A deficiency in piglets with seborrheic eczema ] . - pubmed
Depression of humoral antibody formation in the chicken by thymectomy and antilymphocyte serum . - pubmed
The induction of leukemia and life shortening in mice by continuous low - level external gamma radiation . - pubmed
Extended long term physical training regimes can induce chronic modifications of cardiac function in both healthy individuals and subjects with coronary artery disease . - pubmed
The human hepatoma cell line PLC / PRF / 5 produces tumours and lung metastases in nude athymic mice . - pubmed
Antigens soluble in hot trichloracetic acid from eighteen strains of Pityrosporum ovale were studied using rabbit antiserum to American Type Culture Collection strains 24027 , 12078 , and 14521 . - pubmed
These strains were found to share two antigens , both of which were present in cells of Pityrosporum orbiculare and one of which was present in cells of Pityrosporum pachydermatis , Pityrosporum canus , Candida albicans and Rhodotorula rubrum . - pubmed
The paraclinical findings of 7 patients with distal renal tubular acidosis and nephrolithiasis and nephrocalcinosis , respectively , are discussed . - pubmed
We show that this ' retroviral lox system ' allows the infection of cells and the expression of transferred genes . - pubmed
High - dose doxorubicin , etoposide , and cyclophosphamide with stem cell reinfusion in patients with metastatic or high - risk primary breast cancer . - pubmed
Recent data suggest that selected groups of patients with metastatic disease treated with high - dose chemotherapy and stem cell support may enjoy unmaintained , long - term remission . - pubmed
This study was designed to establish the feasibility of administering the combination of high - dose infusional doxorubicin , etoposide , and cyclophosphamide followed by autologous stem cell rescue in patients with responsive metastatic , or high - risk primary breast cancer . - pubmed
Two patients suffered grade 3 mucositis at the highest level of doxorubicin ( 200 mg / m2 ) . - pubmed
Of 21 patients treated for primary high - risk breast cancer , 19 are recurrence free , with a median follow - up of more than 8 months ( & gt ; or = 4 - 36 months ) . - pubmed
The diverse nature of the mutants isolated from L5178Y cells suggests that the mouse - lymphoma mutagenesis assay is capable of detecting a number of mutation types , enhancing the utility of the assay in studying the range of genetic lesions important in human disease . - pubmed
Myocardial cyclic AMP and norepinephrine content in human heart failure . - pubmed
Impaired production of myocardial cyclic adenosine monophosphate ( cAMP ) is thought to contribute to contractile dysfunction in end stage heart failure , but myocardial cAMP content has not yet been evaluated in heart failure patients in comparison with controls . - pubmed
We therefore measured the myocardial content of cAMP by radioimmunoassay in endomyocardial biopsies from patients in different stages of heart failure and in controls and correlated it with biochemical and functional parameters . - pubmed
Plasma cAMP in 20 heart failure patients ( 22.0 + /- 4.2 pmol.l-1 ) was not different from controls(22.0 + /- 7.8 ) , whereas plasma norepinephrine was increased ( heart failure : 460 + /- 257 pg.ml-1 , controls 182 + /- 49 , P & lt ; 0.001 ) . - pubmed
Myocardial cAMP levels are indistinguishable from controls in human heart failure and therefore do not contribute to a further characterization of the cardiac adrenergic system in these patients . - pubmed
Lytic infection of Escherichia coli biofilms by bacteriophage T4 . - pubmed
Early ischemic injury leads to long - term functional and morphologic deterioration of naive rat kidneys and may contribute to changes of chronic allograft rejection . - pubmed
A homozygous deletion in a small cell lung cancer cell line involving a 3p21 region with a marked instability in yeast artificial chromosomes . - pubmed
A 61 - year - old man developed progressive weakness , numbness , and exercise - induced vascular symptoms in the left hand . - pubmed
To evaluate two different methods of managing segmental skeletal defects , 15 patients treated with the open bone graft ( Papineau ) technique were compared with 17 patients who had intercalary bone transport ( Ilizarov ) management . - pubmed
Both techniques shared several fixator - associated problems such as implant site sepsis and patient discomfort . - pubmed
Experimental colitis in rats induces low - grade endotoxinemia without hepatobiliary abnormalities . - pubmed
In three experimental models in rats , surgical construction of a self - filling blind loop ( SFBL ) , trinitrobenzene sulfonic acid ( TNB ) -induced colitis , and the combination of SFBL and TNB , the hypothesis was studied that intestine - derived endotoxins play a role in the pathogenesis of hepatobiliary disorders in chronic inflammatory bowel disease ( CIBD ) . - pubmed
These results show that low - grade portal and systemic endotoxinemia in rats , induced by bacterial overgrowth and/or chemical colitis , is not able to induce hepatobiliary alterations . - pubmed
To exclude definitively a possible role for portal endotoxinemia in the pathogenesis of CIBD - associated hepatobiliary abnormalities , however , an adequate animal model for CIBD is urgently needed . - pubmed
MATERIALS AND METHODS : A total of 108 patients with clinical shoulder problems and 16 volunteers underwent MR imaging with a 1.5 - T unit . - pubmed
The presence of AC joint fluid was associated with advancing patient age , presence of osteophytes , and fluid in the glenohumeral joint . - pubmed
Gastroesophageal reflux and cow 's milk allergy in infants : a prospective study . - pubmed
OBJECTIVE : The aim of our study was to determine the frequency of the association of gastroesophageal reflux with cow 's milk protein allergy in patients win the first year of life . - pubmed
The cow 's milk - free diet and two successive blind challenges confirmed the diagnosis of cow 's milk allergy in 85 of the 204 patients with gastroesophageal reflux . - pubmed
In all , gastroesophageal reflux was associated with , and probably caused by cow 's milk allergy , in 85 of 204 cases ( 41.8 % ) . - pubmed
CONCLUSIONS : Considering the frequency of this association , patients younger than 12 months old with symptoms of gastroesophageal reflux should be carefully examined to determine whether this disorder is primary or caused by cow 's milk allergy . - pubmed
In addition , re - infection following an episode of self - limited infection or during chronic carrier condition has been described in chimpanzees and in man . - pubmed
daily ) or placebo on erythrocyte membrane cholesterol content and acyl chain composition have been studied in 36 patients with a clinical history of atherosclerosis enrolled in the Oxford Cholesterol Study . - pubmed
We report severe nodulocystic acne in a 21 - year - old man associated with ectrodactyly of the right foot and soft - tissue syndactyly of the third and fourth left fingers , and the first to fourth left toes . - pubmed
Follow - up on 46 of 49 patients revealed recurrence in 27 % ( actual survival 68 % ) ; however all three cases containing tumour cells on immunohistochemistry were free from recurrence . - pubmed
Murine MPS I : insights into the pathogenesis of Hurler syndrome . - pubmed
Here we report on the long - term clinical , biochemical , and pathological course of MPS I in mice with emphasis on the skeletal and central nervous system ( CNS ) manifestations . - pubmed
Skeletal manifestations represent the earliest clinical finding in MPS I mice with histologic analysis of growth plate and cortical bone revealing evidence that significant early pathology is present . - pubmed
This murine model clearly shows phenotypic and pathologic features which mimic those seen in severe human MPS I and should be an invaluable tool for the study of the pathogenesis of generalized storage disorders . - pubmed
The severe bleeding diathesis produced by intoxication with the venom of Lonomia achelous caterpillars is characterized by prolonged bleeding from superficial skin wounds as well as massive hemorrhage into body cavities . - pubmed
[ Diagnostic catheterization and angiography in the examination of patients with ischemic heart disease ] . - pubmed
We herein report the course of two pregnancies in a hypoparathyroid woman treated with calcitriol ( 1,25 ( OH ) 2D3 ) . - pubmed
A 29 - year - old hypoparathyroid woman receiving chronic treatment with calcitriol ( 0.25 microg / day ) and calcium ( 1.5 g / day ) was referred in the 6th week of her first pregnancy . - pubmed
To maintain normocalcaemia the calcitriol dose was increased to 0.5 microg / day during the 33rd week and to 0.75 microg / day shortly before delivery of a healthy girl in the 3 7th week . - pubmed
Obese subjects were divided into three groups according to the OGTT . - pubmed
Furthermore , we discuss the significance of these ganglia in prostatic cancer patients . - pubmed
METHODS : The study group comprised a total of 42 patients , who had all undergone a radical prostatectomy for prostate adenocarcinoma with a relatively small volume . - pubmed
METHODS : Four hundred and thirty - two patients with unstable angina were enrolled . - pubmed
Efficacy was assessed by the number of patients experiencing any episode of recurrent ischaemia as measured by computer - assisted continuous ECG ischaemia monitoring . - pubmed
Minor bleeding and thrombophlebitis occurred more frequently in the efegatran treated patients . - pubmed
During infusions of autologous rat RBCs , Q and total V increased threefold in response to hypoxia , whereas normalized RBC TT ( TTRBC / TTPl ) and normalized tissue hematocrit ( HM / HS ) did not show a significant trend , indicating an increase in the number of pathways through which the RBCs can traverse the network because of spatial recruitment of capillaries . - pubmed
In contrast , during infusions of human RBCs , TTRBC / TTPl and HM / HS decreased significantly in response to hypoxia . - pubmed
Although Q exhibited an increase similar to that during rat RBC infusions , VRBC exhibited a smaller increase compared with VPl , suggesting that reduced RBC deformability leads to a redistribution of RBCs through larger - diameter pathways within the network and exclusion of these RBCs from pathways normally recruited during hypoxia . - pubmed
Antinociceptive effect of ( S )- N - desmethyl trimebutine against a mechanical stimulus in a rat model of peripheral neuropathy . - pubmed
Trimebutine ( 2 - dimethylamino-2 - phenylbutyl 3,4,5 - trimethoxybenzoate , hydrogen maleate ) relieves abdominal pain in humans . - pubmed
In the present study , the antinociceptive action of systemic ( S )- N - desmethyl trimebutine , a stereoisomer of N - monodesmethyl trimebutine , the main metabolite of trimebutine in humans , was studied in a rat model of neuropathic pain produced by chronic constriction injury to the sciatic nerve . - pubmed
[ Study on biliary motility in cirrhotic patients with portal hypertension ] . - pubmed
OBJECTIVE : To study biliary motility in cirrhotic patients with portal hypertension and analyze the relationship between these biliary motility and the degree of liver function . - pubmed
METHODS : Biliary motility function was detected in 40 patients with portal hypertension and 30 normal controls by using quantitative hepatobiliary scintigraphy . - pubmed
CONCLUSION : Cirrhotic patients with portal hypertension often have abnormal motility of gallbladder and biliary duct . - pubmed
Effect of rhythm regularization on left ventricular contractility in patients with atrial fibrillation . - pubmed
In 10 patients with atrial fibrillation , echocardiographic measures of left ventricular function - interval relations were used to assess contractility and to test the hypothesis that rhythm regularization produces a higher contractile state than is seen when the rhythm is irregular . - pubmed
Lymphocytic hypophysitis in a man presenting with hypercalcemia . - pubmed
A 59 - year - old man with a 30 - year history of type 2 diabetes mellitus presented with fatigue , confusion , and weight loss over a 3 - month period . - pubmed
The patient developed pneumonia and adult respiratory distress syndrome and died of an acute myocardial infarction . - pubmed
Pseudohypertension in a patient with diffuse scleroderma . - pubmed
It has been described in patients with uremia , diabetes mellitus , and severe atherosclerosis . - pubmed
We report a case of pseudohypertension in a 65 - year - old man with diffuse scleroderma . - pubmed
This is the first reported case of pseudohypertension in a patient with diffuse scleroderma . - pubmed
Subcutaneous AIT for allergic rhinoconjunctivitis and allergic asthma has been successfully assessed in controlled studies with several clinically important allergens ( i. e. birch- , grass- and mugwortpollen , dust mites , animal dander ) and has shown convincing clinical efficacy . - pubmed
Hymenopteravenom hypersensitivity ( to bee- and wasp venom ) treated with AIT gives the best results compared to AIT with other allergens . - pubmed
BACKGROUND : Diabetic patients are at increased risk for both macrovascular and microvascular disease compared with nondiabetic patients . - pubmed
METHODS : We conducted a prospective observational study to assess the control of multiple predetermined cardiovascular risk factors in 235 treated diabetic patients undergoing elective cardiac catheterization at our institution between December 20 , 1997 , and February 15 , 2000 . - pubmed
One hundred ninety - one ( 81 % ) patients had documented coronary artery disease at cardiac catheterization . - pubmed
The mean Hgb A1c level for all diabetic patients was 8.2 % + /- 1.6 % . - pubmed
PURPOSE : To report the prevalence and clinical significance of ocular findings in 20 patients with Menkes ' syndrome recruited for a clinical trial at the National Institute of Child Health and Human Development ( NICHHD ) . - pubmed
PARTICIPANTS : Twenty patients with Menkes ' syndrome enrolled in a clinical trial at the NICHHD , who underwent ophthalmic evaluation at the National Eye Institute from 1990 through 1997 . - pubmed
MAIN OUTCOME MEASURES : Prevalence of ophthalmic signs of unusual frequency in patients with Menkes ' syndrome . - pubmed
RESULTS : There was a high prevalence of very poor visual acuity ( 8 patients ) , myopia at 21 months old or younger ( 5 of 9 patients this age who underwent cycloplegic refraction ) , strabismus ( 11 of 18 patients whose motility was evaluated ) , blue irides ( 15 of 16 patients whose iris color was documented ) , iris stromal hypoplasia and bilateral peripheral transillumination ( 7 and 3 patients , respectively ) , peripheral retinal hypopigmentation ( 7 of 18 patients whose retinal periphery was noted at the initial examination ) , and aberrant eyelashes ( 5 patients ) . - pubmed
CONCLUSIONS : Patients with Menkes ' syndrome exhibit a high prevalence of several ocular findings , including some ( very poor visual acuity , myopia , strabismus ) that may warrant special care . - pubmed
Early ocular examination is thus indicated for patients with Menkes ' syndrome , particularly those with mild variants of the disease , whose neurologic status is better and lifespan is longer . - pubmed
We report the case of a 67 year old patient admitted at our institution for acute onset of left hemiplegia . - pubmed
Fatty acid analysis of Stenotrophomonas maltophilia clinical strains showing different susceptibility to antibiotics at 30 and 37 degrees C. Isolates of Stenotrophomonas maltophilia species display the feature " temperature - dependent susceptibility " ( TDS ) to antibiotics . - pubmed
RESULTS : Men with the AC / CC genotype exhibited higher blood pressures than men with the AA genotype ; however , this relationship was not found among women . - pubmed
We investigated this question with individuals with neurological damage who suffered from deficits of attention . - pubmed
We presented 4 patients with neurological complications caused by B cell lymphomas as follows . - pubmed
Our first patient was a 67 - year - old woman with primary intracranial lymphoma whose onset simulated that of a cerebral infarct . - pubmed
The second patient was a 52 - year - old man with lymphoma , who developed myelopathy caused by an intradural extramedullary spinal cord tumor . - pubmed
The third was a 80 - year - old man with left cavernous sinus syndrome , which did not respond to therapies against lymphoma . - pubmed
The fourth was a 55 - year - old man who presented with numb chin syndrome on both sides , followed by multifocal lymphomatous involvement of the cranial nerves , spinal roots and leptomeninges . - pubmed
Endosulfan ( 13mg / kg / day body weight ) was administered orally to mices via intragastric - during 10 days . - pubmed
RESULTS : Statistical analysis showed significantly lower results for the patient group in the Hospital for Special Surgery score , the Knee Society score , the patella score , and the Visual Analog Scale for pain . - pubmed
[ Protein utilization on the part of human tumor cells cultivated in vitro ] . - pubmed
On peripheral nerve electrical excitability in rachitic and dystrophic children in the Tohoku district ] . - pubmed
MATERIAL AND METHODS : Ten subjects with gingivitis , but no signs of destructive periodontitis , were recruited . - pubmed
The least - studied clinical association for SOD is in patients with biliary pain and intact gallbladders . - pubmed
Elevated basal sphincter of Oddi pressure is predictive of clinical response to sphincterotomy in patients with postcholecystectomy pain in two randomized sham - controlled studies . - pubmed
However , patients with suspected SOD have the highest complication rate from endoscopic retrograde cholangiogram and sphincterotomy , and , therefore , careful patient selection is mandatory . - pubmed
METHODS : Records were reviewed for all patients seen during a 3 - year period who underwent EUS of the upper - GI tract for staging of known or suspected malignancy . - pubmed
Patients were included if there was histopathologic evidence of malignancy , they had undergone noninvasive liver imaging within 6 weeks of EUS , and liver surveillance was specifically mentioned in the report of the EUS procedure . - pubmed
Liver lesions were seen in 27 patients , 17 of whom had an abnormal noninvasive liver imaging test . - pubmed
EUS - guided FNA of the liver was performed in 21 patients and was diagnostic of malignancy in 15 ( 6.8 % ) , 5 of whom ( 2.3 % ) had normal noninvasive imaging . - pubmed
EUS missed liver lesions in 4 patients known to have abnormalities by other imaging modalities . - pubmed
CONCLUSIONS : EUS can detect occult liver metastases in patients in whom noninvasive hepatic imaging studies are normal , although the frequency at which such lesions are detected is low . - pubmed
[ Long - term curative effect of ventilation tube insertion for otitis media with effusion in adult patients ] . - pubmed
OBJECTIVE : To examine the long - term effect of ventilation tube insertion in treating patients with non - tumor adult - onset otitis media with effusion ( OME ) . - pubmed
During 12 - 18 months following the operation , the ventilation tubes were extruded in 89 patients , among whom 55 had OME recurrence . - pubmed
The recurrence of OME following ventilation tube extrusion was significantly correlated to the pathological changes in the nose or nasopharynx of the patients . - pubmed
Fertility preservation should be an integral part of improving the quality of life in cancer survivors ; however , it is neither possible nor ethical to recommend the same recipe for every cancer patient . - pubmed
Variation in initial state is described by initial body weight ( BW0 ) , from which the chemical composition of the pig is calculated . - pubmed
If all pigs in a group are affected at the same stressor intensity ( e.g. - pubmed
Consequently , decreasing the variation in initial body weight and improving ability of pigs to cope may be a better way of improving pig performance than selecting only for increased growth potential . - pubmed
[ Radiotherapy of venereal tumors of the dog ] . - pubmed
Adjunctive use of atypical antipsychotics and anticholinergic drugs among patients with schizophrenia . - pubmed
METHOD : We identified patients with schizophrenia from outpatient clinics in the Veterans Health Administration ( VA ) and defined initiation of olanzapine or risperidone as patients who were not on any antipsychotics for 6 months and subsequently initiated on the target drug between 1/4/1999 and 31/3/2000 . - pubmed
REVIEW SUMMARY : The frequency of neurologic manifestations , more common in male Behcet patients , is between 5 % and 30 % . - pubmed
CONCLUSION : Neuro - Behcet disease must be considered in the differential diagnosis of stroke in young adults , multiple sclerosis , movement disorders , intracranial hypertension , intracranial sinovenous occlusive diseases , and other neurologic syndromes . - pubmed
Increased late sodium current in myocytes from a canine heart failure model and from failing human heart . - pubmed
We studied I(Na ) in heart failure ventricular cells from a canine pacing model of heart failure and also from explanted failing human hearts . - pubmed
Peak I(Na ) density was significantly decreased by 39 % and 57 % in the dog model and in human heart failure , respectively . - pubmed
The TMD sample comprised 90 patients ( 30 patients with muscle disorders ; 30 patients with disc displacement with reduction ; 30 patients with muscle disorders and disc displacement with reduction ) and was compared with 90 healthy control subjects . - pubmed
A reproducible model of cardiac hypertrophy in rats . - pubmed
CONCLUSION : We have developed a reproducible model of significant left ventricular hypertrophy in rats . - pubmed
Protein chip array profiling analysis of sera from neuroblastoma patients . - pubmed
Neuroblastoma , the most common extracranial solid tumour in children , is characterised by highly heterogeneous clinical behaviour ; patients are stratified into risk categories according to a combination of clinical and biological markers . - pubmed
Aggressive surgical therapy and radiotherapy for patients with high - risk neuroblastoma treated with rapid sequence tandem transplant . - pubmed
BACKGROUND / PURPOSE : The treatment approach for patients with high - risk neuroblastoma has been one of dose intensification chemotherapy and aggressive treatment of the primary tumor . - pubmed
Local tumor control is examined in high - risk patients treated with tandem stem cell transplant , aggressive surgery , and selected radiation therapy ( XRT ) . - pubmed
Two patients had local recurrence after gross total resection . - pubmed
One of the boys also had severe global developmental delay with abnormal findings from magnetic resonance imaging of the brain . - pubmed
Genetic studies implicating the region of human chromosome 18p11.2 in susceptibility to bipolar disorder and schizophrenia have observed parent - of - origin effects that may be explained by genomic imprinting . - pubmed
METHODS : An individual with CFEOM1 ( classic autosomal dominant CFEOM ) and MG underwent a comprehensive ophthalmic examination . - pubmed
OBJECTIVE : To identify predictive factors for work capacity in patients with musculoskeletal disorders . - pubmed
The initial level of proliferative activity of different tumour types of individual patients -- carcinoma of oropharingeal zone , stomach , oesophagys , rectum , glioblastoma have been studied . - pubmed
Acute kidney injury ( AKI ) occurs in about half of patients in septic shock and the mortality of AKI with sepsis is extremely high . - pubmed
All patients complained of symptoms and had a neurophysiological examination that might have indicated CTS . - pubmed
Effect of Shenfu injection on ischemia - reperfusion injury of rat liver graft . - pubmed
BACKGROUND : It is reported that Shenfu injection ( an injection prepared from traditional Chinese medicines red ginseng and aconite root ) can decrease the extent of ischemia - reperfusion injury to many organs , such as the heart and kidney . - pubmed
We therefore investigated the effect of Shenfu injection on ischemia - reperfusion injury of rat liver graft and its mechanism . - pubmed
CONCLUSIONS : Shenfu injection has protective effect on ischemia - reperfusion injury of rat liver graft . - pubmed
PURPOSE : To determine whether evidence - based standards exist regarding the indications for orbital exenteration in patients with orbital mucormycosis . - pubmed
Reversible posterior leukoencephalopathy syndrome after repeat intermediate - dose cytarabine chemotherapy in a patient with acute myeloid leukemia . - pubmed
A 56 - year - old man was admitted to our hospital with leukocytosis , anemia , and thrombocytopenia . - pubmed
On day 15 after the final infusion of cytarabine , the patient suffered headache , and on day 21 , he experienced a decrease in sensation on the sole of his left foot . - pubmed
Working memory related gamma oscillations in schizophrenia patients . - pubmed
Recent reports show that the capability of neural networks supporting high - frequency synchronization is reduced in the brain of schizophrenia patients . - pubmed
Specifically , deficits in gamma activity have been shown in schizophrenia patients during perception and simple cognitive tasks . - pubmed
The main objective of this study was to investigate modulation of event - related gamma responses in tasks varying working memory ( WM ) load in schizophrenia patients ( N=10 ) and healthy controls ( N=10 ) . - pubmed
During all three tasks schizophrenia patients showed significantly slower reaction times and higher error rates than controls . - pubmed
These results suggest that healthy subjects used various cognitive strategies depending on task difficulty , while schizophrenia patients needed to initiate complex cognitive processes similar to those used during processing of novel contexts or stimuli even for the simple choice reaction task with low cognitive demand . - pubmed
Prior reports on patients with myotonic muscular dystrophy , multiple sclerosis , Parkinson ' s disease , and amyotrophic lateral sclerosis , have shown beneficial effects of modafinil in treating fatigue . - pubmed
We report 4 patients with genetically confirmed Charcot - Marie - Tooth disease who had significant fatigue that was almost completely relieved by modafinil . - pubmed
Long - term treatment of patients with recurrent unipolar major depression : evidence to clinical practice . - pubmed
Yersinia ruckeri causes the enteric redmouth disease or yersiniosis , an important systemic fish infection . - pubmed
Epizootic of tularemia in an outdoor housed group of cynomolgus monkeys ( Macaca fascicularis ) . - pubmed
Tularemia is a highly contagious infectious zoonosis , transmissible by inoculation , ingestion , or inhalation of the infectious agent Francisella tularensis . - pubmed
Pathologic findings were similar in all monkeys that died and resembled the clinical picture of the human disease , including an ulceroglandular syndrome with local lymphadenopathy , gingivostomatitis , and systemic spread , with manifestations such as subacute necrotizing hepatitis , granulomatous splenitis , and pneumonia . - pubmed
This is the largest outbreak in nonhuman primates and the first report of tularemia in cynomolgus monkeys . - pubmed
An overview of the recent literature about tularemia in nonhuman primates is given . - pubmed
We report a 65 - year - old female patient who demonstrated cardiac perforation , pulmonary cement embolism , and tricuspid regurgitation , and these were all caused by venous leakage of polymethylmethacrylate as a complication of the procedure . - pubmed
MATERIALS AND METHODS : Between April 1987 and December 1991 , 241 THAs with insertion of an ARRH were performed in 178 unselected , consecutive patients ( average age 58 years ; range 30 - 84 years ) with a secondary osteoarthrosis in 41 % of the cases . - pubmed
Patients with pathologic diagnosis of invasive breast carcinoma & lt;20 mm in size ( pT1 ) and undergoing BCT were selected . - pubmed
RESULTS : Of 206 patients who underwent BCT for pT1 tumors , 84 ( 41 % ) needed re - excision . - pubmed
CONCLUSIONS : These predictive factors could be useful in reducing the rate of re - excision as well as in identifying patients with multifocal tumors and/or extensive in situ carcinoma whose disease would be better managed by mastectomy . - pubmed
Furthermore , chemically induced changes in gene regulation are associated with serious and complex human diseases , including cancer , diabetes and obesity , infertility , respiratory diseases , allergies , and neurodegenerative disorders such as Parkinson and Alzheimer diseases . - pubmed
METHODS : Three unrelated patients with congenital myopathy were investigated by muscle biopsy and genetic analysis . - pubmed
RESULTS : All three patients had early - onset muscle weakness of variable severity and distribution . - pubmed
The patient died on postoperative Day 5 from cardiac arrest . - pubmed
Sixty - four Korean schizophrenic patients were enrolled . - pubmed
Chronobiology of arterial hypertension in hemodialysis patients : implications for home blood pressure monitoring . - pubmed
METHOD : Data were collected from 71 participants ( 30 females , 41 males ) with CP ( Gross Motor Function Classification System [ GMFCS ] levels I - V ) between the ages of 8 and 18 years . - pubmed
Meningitis from an uncommon serotype of Streptococcus pneumoniae in a young child . - pubmed
Typhoid Meningitis : Cultivation of Bacillus typhosus from Meninges and mesenteric Lymph Node in a Case of General Paresis , with Note on Experimental Typhoid Meningitis in the Guinea - Pig . - pubmed
Phase I / II clinical trials of I d vaccination in lymphoma demonstrated that some lymphoma patients could mount immune responses that were correlated with a favorable clinical outcome . - pubmed
Although I d vaccines induce immune responses in myeloma patients , their efficacy is insufficient to provide a clear clinical benefit . - pubmed
Severe peritonitis due to Streptococcus viridans following adjustable gastric banding . - pubmed
Streptococci is a significant cause of peritoneal dialysis peritonitis ( 6 % to 16 % of the cases ) , and S. - pubmed
However , peritonitis due to S. - pubmed
We herein report a non - uremic case of a 38 - year - old male patient with severe peritonitis due to S. - pubmed
Epidemic encephalitis in military personnel ; isolation of Japanese B virus on Okinawa in 1945 , serologic diagnosis , clinical manifestations , epidemiologic aspects and use of mouse brain vaccine . - pubmed
An actinomycete , designated strain GIMN4.002(T ) , was isolated from a tomato rhizosphere soil sample in Guangzhou , China . - pubmed
Further , the morphological , physiological and biochemical characteristics of strain GIMN4.002(T ) are distinct from S. - pubmed
On the basis of the physiological and molecular properties observed , it is proposed that strain GIMN4.002(T ) represents a novel species of the genus Streptomyces , for which the name Streptomyces caeruleatus sp . - pubmed
We sought to investigate the impact of preoperative LV diastolic function on outcomes after SVR in patients with heart failure . - pubmed
METHODS : Sixty - seven patients ( 60 + /- 14 years ) with LV systolic dysfunction ( LV ejection fraction , 0.27 + /- 0.10 ) underwent SVR . - pubmed
CONCLUSIONS : In patients with LV systolic dysfunction undergoing SVR , preoperative restrictive LV diastolic filling pattern strongly related to higher mortality with aggravation of LV systolic function , mitral regurgitation grade , or LV remodeling . - pubmed
Efficacy of guided imagery with theta music for advanced cancer patients with dyspnea : a pilot study . - pubmed
BACKGROUND : Dyspnea is a frequent and devastating symptom among advanced cancer patients for which improved and low - cost palliative techniques are needed . - pubmed
METHODS : A one - group repeated measures research design investigated the efficacy of guided imagery ( GI ) with theta music ( M ) on dyspnea in advanced cancer patients . - pubmed
RESULTS : Participants included 53 patients , 33 % with lung cancer . - pubmed
DISCUSSION : This study demonstrates that GI / M is a useful intervention for palliative care of patients with dyspnea . - pubmed
METHODS : Plasma metabolic products in patients of coronary heart disease ( CHD ) with XBSS or non - XBSS and subjects in the control group were identified by gas chromatographic mass spectrometry ( GC - MS ) type QP2010 , the changes of their main elements in different groups were analyzed by principal components analysis ( PCA ) and partial least squares ( PLS ) analysis . - pubmed
Discrepancy analysis on 11 changeful metabolites showed that the contents of arachidonic acid , octadecanoic acid , lactic acid , urea , beta - hydroxy butanoic acid and oleic acid increased in CHD patients , especially in those with XBSS ( P & lt ; 0.01 ) . - pubmed
In CHD patients , contents of lactic acid , beta - hydroxy butanoic acid , linoleic acid and glucose in patients of XBSS pattern were higher than in non - XBSS pattern ( P & lt ; 0.01 ) ; content of linoleic acid , glucose , alanine and proline decreased in non - XBSS pattern while increased in XBSS pattern . - pubmed
Content of glucose in CHD - XBSS patients was significantly higher than that in the healthy control ( P & lt ; 0.01 ) . - pubmed
Content of citric acid was lower in CHD patients , and showed significant difference between that in CHD - XBSS patients and healthy control ( P & lt ; 0.01 ) . - pubmed
CONCLUSIONS : The major plasmic metabolites in CHD - XBSS patients are arachidonic acid , octadecanoic acid , lactic acid , urea , citric acid , beta - hydroxybutyric acid , oleic acid , glucose , and alanine . - pubmed
Developmental changes of gene expression after spinal cord injury in neonatal opossums . - pubmed
Changes in gene expression have been measured 24h after injury to mammalian spinal cords that can and can not regenerate . - pubmed
By the use of marsupial cDNA microarrays , we detected 158 genes that respond differentially to injury at the two ages critical for regeneration . - pubmed
Intensive chemotherapy for a relapsed ALL patient who received living - donor lobar lung transplantation . - pubmed
METHODS : Two investigators independently conducted a MEDLINE search from 1 January 2007 through 30 June 2010 for all publications reporting EoE in human subjects , and also searched the proceedings of the 2007 - 2010 American College of Gastroenterology and American Gastroenterological Association meetings , using a predefined search strategy . - pubmed
Left ventricular inflow tract obstruction secondary to a myxoma in a dog . - pubmed
This is the first description of a left ventricular inflow tract obstruction secondary to a myxoma in a dog . - pubmed
A 4 yr old , male fox terrier presented with a 1 mo history of cough and exercise intolerance . - pubmed
Eleven months after diagnosis , the dog was euthanized at the owner 's request because of recurrent congestive heart failure . - pubmed
Vibratome - cut myocardial slices were prepared from left ventricular biopsies obtained from end - stage heart failure patients undergoing heart transplant or ventricular assist device implantation , and from hearts of normal dogs . - pubmed
We conclude that viable myocardial slices with preserved structural , biochemical and electrophysiological properties can be prepared from adult human and canine heart biopsies and offer a novel preparation suitable for the study of heart failure and drug screening . - pubmed
OBJECTIVE : To investigate the levels of serum cortisol in patients with uncomplicated Plasmodium falciparum ( P. falciparum ) malaria in an area of unstable malaria transmission in eastern Sudan . - pubmed
METHODS : The concentrations of cortisol were measured in sera of 25 patients with uncomplicated P. falciparum malaria ( at presentation , 24 h and 7 d later ) and 25 healthy volunteers using radioimmunoassay gamma counter . - pubmed
RESULTS : There was no significant difference in mean ( SD ) of total cortisol levels in patients with malaria in comparison with the control group ; 602.2 ( 369.6 ) vs. 449.2(311.7 ) ng / mL , P=0.12 . - pubmed
In patients with uncomplicated P. falciparum malaria , the mean ( SD ) presenting cortisol levels were significantly higher in comparison to the levels on day 7 ; 602.2 ( 369.6 ) vs. 373.6(139.1 ) ng / mL , P=0.009 . - pubmed
In the patients with uncomplicated P. falciparum malaria ( on presentation ) cortisol levels were not correlated with initial temperature or the presenting parasitaemia . - pubmed
Streptococcus parauberis isolates were divided into two serologically distinct types ( serotype 1 and serotype 2 ) , except for one strain ( S1091 ) , using an agglutination assay with rabbit antiserum , and serotype 1 was identified as the dominant type ( 24 of 29 isolates ) in this study . - pubmed
In the pathogenicity test , the serotype 1 strains induced significantly higher mortality than the serotype 2 strains in olive flounder when experimentally inoculated via the intraperitoneal route . - pubmed
Attenuation of nonenzymatic glycation , hyperglycemia , and hyperlipidemia in streptozotocin - induced diabetic rats by chloroform leaf extract of Azadirachta indica . - pubmed
BACKGROUND : The hypoglycemic effects of hexane , chloroform and methanol extracts of leaves of Azadirachta indica ( AI ) were evaluated by oral administration in streptozotocin - induced severe diabetic rats ( SD ) . - pubmed
MATERIALS AND METHODS : The effect of chronic oral administration of the extract for 28 days was evaluated in streptozotozin diabetic rats . - pubmed
CONCLUSION : Azadirachta indica can improve hyperlipidemia and hyperinsulinema in streptozocin - induced diabetic rats and , therefore , AI can be potentially considered to be an antidiabetic - safe agent . - pubmed
METHODS : Sera were obtained from 40 periodontitis patients and 30 control subjects . - pubmed
RESULTS : Periodontitis patients demonstrated significantly higher serum antibody titer to P. - pubmed
RESULTS : Four patients underwent the modified combined approach after tumor resection and prior to postoperative radiotherapy in three of the four cases . - pubmed
The patient underwent surgical management with diagnosis of sigmoid volvulus . - pubmed
STUDY DESIGN : We analyzed data from 101 women randomized to undergo abortion with routine pain control measures only ( ibuprofen and paracervical block ) or with the addition of intraoperative music via headphones . - pubmed
PVX - potyvirus synergistic infections differentially alter microRNA accumulation in Nicotiana benthamiana . - pubmed
In comparison to single infections , co - infection of Nicotiana benthamiana with Potato virus X ( PVX ) and Potato virus Y ( PVY ) or Plum pox virus ( PPV ) , resulted in increased systemic symptoms ( synergism in pathology ) . - pubmed
Our studies revealed that double infection by PVX and PVY or PPV that produced the most severe symptoms in N. - pubmed
These findings indicate a differential effect on miRNA metabolism of the combined infection by two unrelated plant viruses , which may account in part for the severe symptoms caused by PVX / potyvirus - associated synergisms . - pubmed
Subsequently , this concentration was tested in 2 herds with high and low bovine tuberculosis prevalence , the latter with paratuberculosis coinfection . - pubmed
The protein cocktail did not induce reactions in tuberculosis - free cattle or in paratuberculosis - infected cattle . - pubmed
We have also reported , for the first time in general practice , the presence of seasonal and pandemic influenza viruses in the stools of adult patients consulting for uncomplicated AD . - pubmed
A simultaneous investigation of enteric and influenza viruses in patients complaining of gastrointestinal symptoms could be useful for future studies to better identify the agents responsible for AD . - pubmed
The risk of developing IAH is minimal in mechanically ventilated patients with positive end - expiratory pressure & lt ; 10 cmH2O , PaO2 / FiO2 & gt ; 300 , and BMI & lt ; 30 and without pancreatitis , hepatic failure / cirrhosis with ascites , gastrointestinal bleeding or laparotomy and the use of vasopressors / inotropes on admission . - pubmed
Transcatheter closure of a large ASD from the femoral vein in a patient with Budd - Chiari syndrome . - pubmed
Anomalies of the inferior vena cava are rare in patients with isolated atrial septal defect ( ASD ) . - pubmed
Correlation of the gastroesophageal flap valve grade with the surgery rate in patients with gastroesophageal reflux disease . - pubmed
METHODS : For 453 patients with symptoms suggestive of GERD , GEFV grading and 24 - h ambulatory pH monitoring were performed . - pubmed
We report successful closure of ASD associated with RAA using a 26 - mm atrial septal occluder in a 30 - year - old male patient . - pubmed
In this case report , we review the experience of a patient who presented with early stage pancreatic cancer ( Stage IIb ) who underwent a Whipple procedure and adjuvant chemoradiation . - pubmed
As soon as the patient started gemcitabine chemotherapy the patient developed gouty arthritis again , requiring discontinuation of chemotherapy . - pubmed
The patient received no additional treatment until his recent recurrence 8 months later where gemcitabine chemotherapy was again introduced with prophylactic medications consisting of allopurinol 100 mg by mouth daily and colchicine 0.6 mg by mouth daily throughout gemcitabine chemotherapy , and no signs of gouty arthritis occurred . - pubmed
Further monitoring and management may be required in patients receiving gemcitabine chemotherapy with underlying gout . - pubmed
BACKGROUND : There are few data addressing local - regional recurrence ( LRR ) and salvage therapies in patients treated with neoadjuvant chemotherapy ( NCT ) compared to those treated with surgery first . - pubmed
RESULTS : 56 patients had a LRR , for a crude recurrence rate of 3 % . - pubmed
For patients with potentially curable recurrence ( excluding distant metastases within 3 months of LRR ) , the 5 - year OS , LC , and DMFS rates were 52 , 77 , and 69 % . - pubmed
CONCLUSIONS : LRR is an uncommon event after BCT and many patients with LRR remain curable ( 5 - year OS & gt;50 % ) . - pubmed
Our data indicate that NCT does not compromise salvage after LRR , providing further assurance that this strategy is safe for appropriately selected breast cancer patients . - pubmed
Compared to either single vaccine , HUVEC - HDM induced a more significant inhibition on the growth and metastasis of H22 hepatocellular carcinoma in mice and prolonged the survival of tumor - bearing mice . - pubmed
These results not only highlight the superiority of the combined HUVEC - HDM treatment regimen , but also support the translation of such approaches into the clinic for the treatment of patients with hepatocellular carcinoma . - pubmed
The most common cause of asthma exacerbations is viral respiratory infections , particularly human rhinovirus ( HRV ) . - pubmed
METHODS : We used an in vitro coculture model of primary human eosinophils and the BEAS-2B epithelial cell line either stimulated with HRV1A infection or polyinosinic - polycytidylic acid ( poly [ I : C ] ) . - pubmed
Efficacy of TACE in TIPS patients : comparison of treatment response to chemoembolization for hepatocellular carcinoma in patients with and without a transjugular intrahepatic portosystemic shunt . - pubmed
PURPOSE : To compare treatment response after transarterial chemoembolization ( TACE ) for hepatocellular carcinoma ( HCC ) in patients with and without a transjugular intrahepatic portosystemic shunt ( TIPS ) . - pubmed
MATERIALS AND METHODS : A retrospective review of patients who underwent conventional TACE for HCC between January 2005 and December 2009 identified 10 patients with patent TIPS . - pubmed
From the same time period , 23 patients without TIPS were selected to control for comparable Model for End - Stage Liver Disease and Child - Pugh - Turcotte scores . - pubmed
OBJECTIVE : To observe clinical and laboratory features of valproic acid - induced hyperammonaemic encephalopathy in patients taking valproic acid . - pubmed
Ten patients on valproic acid therapy of any age group with idiopathic or secondary epilepsy , who presented with encephalopathic symptoms , were registered and followed up during the study . - pubmed
RESULTS : Hyperammonaemia was found in all patients with encephalopathic symptoms . - pubmed
All patients taking valproic acid presenting with encephalopathic symptoms must be monitored for the condition . - pubmed
Synergistic effect of cisplatin and synchrotron irradiation on F98 gliomas growing in nude mice . - pubmed
This protocol showed a cure of 33 % of rats bearing the F98 glioma but the efficiency of the treatment was only measured in terms of overall survival . - pubmed
Firstly , changes in tumor growth of the F98 glioma implanted in the hindlimb of nude mice after the PAT - Plat treatment and its different modalities have been characterized . - pubmed
OBJECTIVES : To assess the effectiveness of chest physiotherapy in relation to time until clinical resolution in children ( from birth up to 18 years old ) of either gender with any type of pneumonia . - pubmed
Cervical carcinogenesis is a consequence of persistent infection with high - risk human papillomaviruses ( HPVs ) . - pubmed
Recent studies indicate that HPV - transformed cells actively instruct their microenvironment to promote carcinogenesis . - pubmed
However , detailed analysis by two - dimensional immunoblotting and mass spectrometry showed that three spots originating from betaA1 - crystallin were detected only in sera from cataract patients . - pubmed
Chromosome 10 , frequently lost in human melanoma , encodes multiple tumor - suppressive functions . - pubmed
METHODS : The participants of this study were the patients who have undergone chest CT for the examination of pulmonary diseases in our institute . - pubmed
METHODS : Clinical data of 115 patients with metachronous liver metastasis in Tianjin Medical University Cancer Institute and Hospital between 1996 and 2008 were analyzed retrospectively . - pubmed
RESULTS : Among 115 patients , the 1- , 3- and 5 - year non - hepatic metastasis rates were 45.3 % , 14.8 % and 3.5 % respectively . - pubmed
CONCLUSIONS : The size of gastric cancer , vascular invasion , tumor differentiation and lymph node metastasis are important factors associated with the risk of hepatic metastasis from gastric cancer in patients after radical gastrectomy . - pubmed
We report a case of intraosseous mucoepidermoid carcinoma of the mandible in an 80 - year old female patient developing from a previously diagnosed dentigerous cyst . - pubmed
Prospective monitoring of cytomegalovirus , Epstein - Barr virus , BK virus , and JC virus infections on belatacept therapy after a kidney transplant . - pubmed
The aim of this single - center study was to compare the incidence of viral infections ( cytomegalovirus , Epstein Barr virus , BK virus , and JC virus ) , in 62 de novo kidney transplant patients enrolled in the BENEFIT studies , receiving either belatacept ( n=42 ) or cyclosporine ( n=20 ) . - pubmed
Treatment of patients with suspected brain tuberculoma before or without bacteriologic confirmation in endemic places : report of two cases . - pubmed
Reconstruction of urethral strictures in patients with a long history of blind urethral dilatation . - pubmed
Sixty patients with a long history of blind urethral dilatation ( group 1 ) were compared with 47 patients without prior dilatations ( group 2 ) . - pubmed
The greatest improvement in symptoms and quality of life occurred three months after the surgery ( P & lt ; .05).Postoperative infection was persistent in 20/107 ( 18.7 % ) patients . - pubmed
RESULTS : A proposed management guideline for patients with penetrating abdominal trauma was created . - pubmed
BACKGROUND & amp ; AIMS : Differences in intrahepatic gene expression patterns may be associated with therapy response in peginterferon - treated chronic hepatitis B ( CHB ) patients . - pubmed
Genes upregulated in responders exhibited strongest similarity with a set of genes induced in livers of chimpanzees with acute Hepatitis B infection . - pubmed
Acute myocardial infarction patients were excluded . - pubmed
Primary intra- and juxta - articular vascular malformations of the temporomandibular joint : a clinical analysis of 8 consecutive patients . - pubmed
PATIENTS AND METHODS : This study retrospectively reviewed eight patients ( seven venous malformations and one lymphatico - venous malformation ) who were treated for intra - or juxta - articular vascular malformations of the temporomandibular joint from November 2005 to January 2011 . - pubmed
All treated patients had no clinical or radiographic signs of recurrence . - pubmed
We report here a patient with generalized poikilodermatous skin lesions whose diagnosis of mycosis fungoides was made only a few years after the onset of his disease due to its bizarre clinical behavior and a natural reluctance to diagnose this disease in children and adolescents . - pubmed
Recent studies of beta - adrenergic antagonists suggest they may have neuroprotective effects that lead to improved functional outcomes in rodent models of ischemic stroke ; however , there are limited data in patients . - pubmed
We aimed to determine whether there was an improvement in mortality rates among patients who were taking beta - blockers during the acute phase of their ischemic stroke . - pubmed
METHODS : A retrospective analysis of a prospectively collected database of ischemic stroke patients was performed . - pubmed
CONCLUSIONS : The continuation of home beta - adrenergic antagonist medication during the first 3 days of hospitalization after an ischemic stroke is associated with a decrease in patient mortality . - pubmed
This supports the work done in rodent models suggesting neuroprotective effects of beta - blockers after ischemic stroke . - pubmed
Previous clinical study has demonstrated that 30 - 40 % of patients undergoing pancreaticoduodenectomy ( PD ) developed hepatic steatosis . - pubmed
Recently we encountered two patients with PD who later developed NASH diagnosed by liver biopsy . - pubmed
Case 1 was a 79 - year - old woman who underwent PD for intraductal papillary mucinous neoplasm ( IPMN ) . - pubmed
Case 2 was a 71 - year - old woman who underwent PD for IPMN . - pubmed
For each patient , treatment of infection and high - dose pancreatic enzyme supplements improved liver dysfunction and liver steatosis . - pubmed
The aim of this study was to evaluate , in a large cohort of chronically transfused patients , whether the presence of extramedullary hematopoiesis ( EMH ) accounts for the typical patterns of cardiac iron distribution and/or cardiac function parameters . - pubmed
We retrospectively selected 1,266 thalassemia major patients who had undergone regular transfusions ( 611 men and 655 women ; mean age : 31.3 + - 8.9 years , range : 4.2 - 66.6 years ) and were consecutively enrolled within the Myocardial Iron Overload in Thalassemia network . - pubmed
EMH was detected in 167 ( 13.2 % ) patients . - pubmed
The role of outpatient ambulatory electroencephalography in the diagnosis and management of adults with epilepsy or nonepileptic attack disorder : A systematic literature review . - pubmed
Electroencephalography ( EEG ) is an established diagnostic tool with important implications for the clinical management of patients with epilepsy or nonepileptic attack disorder . - pubmed
In this paper , we present the results of a systematic review of the scientific literature on the use of AEEG in the diagnosis of epilepsy and nonepileptic attacks in adult patients . - pubmed
A 44 - year - old man was referred to the hospital with rightsided diminished hearing for 7 weeks , left - sided facial palsy for 2 weeks , and left - sided sensorineural hearing loss for 1 week . - pubmed
Despite the recent advances in the development of antitumor therapies , the prognosis for patients with malignant gliomas remains dismal . - pubmed
To determine whether AIs produce hypersensitivity in animal models of pain , we examined the effects of the AI , letrozole , on mechanical , thermal , and chemical sensitivity in rats . - pubmed
Repeated injection of 5mg / kg letrozole in male rats produced mechanical , but not thermal , hypersensitivity that extinguished when drug dosing was stopped . - pubmed
To determine whether sensitization of sensory neurons contributed to AI - induced hypersensitivity , we evaluated the excitability of neurons isolated from dorsal root ganglia of male rats chronically treated with letrozole . - pubmed
These results provide the first evidence that AIs modulate the excitability of sensory neurons , which may be a primary mechanism for the effect of these drugs to augment pain behaviors in rats . - pubmed
The interpretation and discussion of these data and further extensive insights into drug discovery against tuberculosis from natural products of plant biodiversity can be found in " Antimycobacterial and cytotoxic activity of selected medicinal plant extracts " [ 2 ] . - pubmed
Onychomycosis due to Candida parapsilosis in a Child with Ventricular Septal Defect : An Unusual Predisposition . - pubmed
Candida parapsilosis is emerging as a potential pathogen for onychomycosis . - pubmed
STUDY DESIGN : We studied 20 neonates who were admitted with a diagnosis of HIE in the neonatal intensive care unit . - pubmed
Cancer gene panel analysis of cultured circulating tumor cells and primary tumor tissue from patients with breast cancer . - pubmed
Although numerous effective therapies have improved the survival rate of patients with breast cancer , a number of patients present with tumor recurrence and metastasis . - pubmed
The analgesic mechanism of subcutaneous injections of diluted bee venom into an acupoint is thought to be part of an anti - inflammatory effect and the central modulation of pain processing . - pubmed
Outcome Measures Changes in the rats ' pain thresholds were assessed by evaluation of pain - related behavior , using a tail flick latency unit . - pubmed
Multimodality treatment including macroscopic complete resection ( MCR ) is currently the most effective therapy for patients with malignant pleural mesothelioma ( MPM ) . - pubmed
Quantification of Salmonella Survival and Infection in an In vitro Model of the Human Intestinal Tract as Proxy for Foodborne Pathogens . - pubmed
Five strains of Salmonella Heidelberg and one strain of Salmonella Typhimurium were used to assess the robustness of the system . - pubmed
Heidelberg strains originated from an outbreak , the fifth S. Heidelberg strain and the S . - pubmed
Recent discoveries have demonstrated the presence of inflammation propagating substrates in the central nervous system of patients afflicted with ALS . - pubmed
METHODS : A retrospective review of 80 patients ( 95 feet ) undergoing surgical treatment for hallux rigidus was performed . - pubmed
Smoking is inversely associated with possessing HPV antibodies from a past infection suggesting that smoking may influence acquiring subsequent infections . - pubmed
METHODS : In a cohort of 1976 U.S. women , we evaluate whether reduced antibodies to HPV-16 is a mechanism for smoking 's role on acquiring a subsequent HPV-16 infection , through the analytic technique of causal mediation analysis . - pubmed
The results support current smoking as a risk factor earlier in the natural history of HPV and are consistent with the hypothesis that smoking increases the risk of a subsequent infection by reducing immunity . - pubmed
A broad variety of rodent motor tests are available to determine deficits after stroke or TBI . - pubmed
The pathogenesis and etiology of pancreatic cancer remain to be fully elucidated ; therefore , associated investigations are required to improve the outcome and prognosis of patients . - pubmed
The sole isoprenoid quinone of strain NS08 T was menaquinone MK-6 and the DNA G+C content was 39.4 mol% . - pubmed
The polar lipid compositions of strain NS08 T and the type strain of the type species of the genus Aquimarina , Aquimarina muelleri KCTC 12285 T , were very similar with phosphatidylethanolamine , an unidentified aminolipid and two unknown polar lipids as the major components . - pubmed
New compound 1 was evaluated for its cytotoxicities against five human cancer cell lines : HL-60 , SMMC-7721 , A-549 , MCF-7 and SW480 . - pubmed
Compound 1 showed significant inhibitory effects against various human cancer cell lines with IC50 values ranging from 0.82 to 8.53 muM. - pubmed
Global lipid profiling of pooled serum samples from 10 patients currently with MDD ( cMDD ) , 10 patients with remitted MDD ( rMDD ) , and 10 healthy controls revealed 37 differentially regulated lipids ( DRLs ) . - pubmed
Previous studies suggest reduced cortical thickness in patients with obesity . - pubmed
This study provides preliminary evidence of brain change following surgery , suggests increases in cerebral cortical thickness in patients with greater excess weight loss , and indicates the need for further investigation using larger samples and correlation with neurocognitive measures , such as memory recall . - pubmed
No studies have assessed sensitivity to reinforcement contingencies that specifically select highly variable response patterns in mice , let alone in models of neurodevelopmental disorders involving limited response variation . - pubmed
Operant variability and incremental repeated acquisition ( IRA ) were used to assess unique aspects of behavioral variability of two mouse strains : BALB / c , a model of some deficits in ASD , and C57Bl/6 . - pubmed
Strain differences emerged , however , after novel learning sequences began alternating with the performance sequence : BALB / c mice substantially outperformed C57Bl/6 mice . - pubmed
These findings constrain the use of BALB / c mice as a model of ASD , but once again reveal this strain is highly sensitive to reinforcement contingencies and they are fast and robust learners . - pubmed
Autoantibody profile and clinical patterns in 619 Italian patients with cutaneous lupus erythematosus . - pubmed
Improvements have been made in the outcomes of patients with NSCLC due to advancements in radiotherapy ( RT ) techniques , the use of concurrent chemotherapy with RT , and the emergence of immunotherapy as first- and second - line treatment in the metastatic setting . - pubmed
RT remains the mainstay treatment in patients with inoperable early - stage NSCLC and is given concurrently or sequentially with chemotherapy in patients with locally advanced unresectable disease . - pubmed
Here , we describe the rationale for the integration of RT and immunotherapy in patients with NSCLC , present safety and efficacy data that support this combination strategy , review planned and ongoing studies , and highlight unanswered questions and future research needs . - pubmed
First , advances in radiological imaging have suggested that a primary breast tumor is absent in OBC patients . - pubmed
Next , the Delta1 viruses were used to determine the hierarchy of immunodominance by measuring the hemagglutination inhibition reactivity of mouse antisera and plasma from 18 human subjects before and after seasonal influenza vaccination in 2017 - 2018 . - pubmed
This study revealed that antigenic site B is immunodominant in the H3N2 influenza virus strain included in the current vaccine preparations . - pubmed
Intragenomic polymorphism and intergenomic recombination in the ribosomal RNA genes of strains belonging to a yeast species Pichia membranifaciens . - pubmed
In this study , we clearly showed that significant polymorphisms of the internal transcribed spacers ( ITS1 and ITS2 ) of ribosomal DNA ( rDNA ) exist within the genome of a strain of the yeast species Pichia membranifaciens . - pubmed
Using a C57BL6 / J mouse model of diet - induced obesity , we show that mannose supplementation of high - fat - diet - fed mice prevents weight gain , lowers adiposity , reduces liver steatosis , increases endurance and maximal O2 consumption , and improves glucose tolerance . - pubmed
Selenium amelioration of arsenic toxicity in rice shows genotypic variation : A transcriptomic and biochemical analysis . - pubmed
Significant decrease in As accumulation , H2O2 content , and fluorescent intensity of nitric oxide ( NO ) , reactive oxygen species ( ROS ) , and superoxide radical ( O2.- ) along with cell death with Se supplementation in both rice varieties demonstrated the protective role of Se as a probable ROS quencher . - pubmed
CONCLUSIONS : This exploratory study found trialling an adapted approach to the Alert Program that uses sensorimotor - based approach decreased tic severity in children with tic disorders . - pubmed
Implementation of tranexamic acid for bleeding trauma patients : a longitudinal and cross - sectional study . - pubmed
RESULTS : Among 228 250 patients , the proportion of trauma patients treated with TXA increased from near zero in 2010 to 10 % ( 4593 ) in 2016 . - pubmed
CONCLUSIONS : There is a low proportion of patients treated with TXA across the range of injury severity and the range of physiological indicators of severity of bleeding . - pubmed
Most patients receive treatment within the existing target of 3 hours from injury , however there remains the potential to further improve major trauma outcomes by the earlier treatment of a wider patient group . - pubmed
This article describes the clinical presentation , our treatment approach , and short - term outcomes for three pediatric patients with multiligamentous injuries of the knee and reviews the current literature relating to these uncommon injuries . - pubmed
CONCLUSION : This multi - electrode ablation catheter could cause minor injury to renal artery instantly after RDN , but it is found to be safe in the animal model at 1 - month follow - up . - pubmed
Brain metabolism modulates neuronal excitability in a mouse model of pyruvate dehydrogenase deficiency . - pubmed
However , the principles that govern their relationship are not always intuitive because heritable defects of brain glucose metabolism are associated with the paradoxical coexistence , in the same individual , of episodic neuronal hyperexcitation ( seizures ) with reduced basal cerebral electrical activity . - pubmed
Does lumbar mobilization help stroke patients to improve functional outcomes ? - pubmed
The current study aimed to observe effects of lumbar mobilization on gait of stroke patients . - pubmed
Quasiinterventional study was conducted on 30 stroke survivors . - pubmed
Sample included either gender with onset of stroke ( & gt;03 - months ) , patients with other pathologies were excluded . - pubmed
The Current study suggested lumbarmobilization to be effective in improving gait in stroke survivors . - pubmed
Lengthening temporalis myoplasty and reduction of the swallowing oral phase dysfunction in facial palsy patients . - pubmed
The aim of this study was to determine whether lengthening temporalis myoplasty could reduce the dysfunction in the oral phase of swallowing in patients with facial palsy . - pubmed
METHODS : 158 patients with BC treated in Yantai Yuhuangding Hospital from September 2015 to December 2017 were retrospectively analyzed . - pubmed
Methods Between January 2003 and June 2008 , 150 patients were treated with radiosurgery for classical or symptomatic TN . - pubmed
Conclusion Immediate pain relief leads to sustained relief and patients present significantly better pain outcomes in comparison to those without immediate relief . - pubmed
Objective : To report our single - center experience in terms of patient clinical characteristics , treatment outcomes , and chemotherapy - related toxicities in patients with low - risk gestational trophoblastic neoplasia ( GTN ) . - pubmed
No patient developed MTX - related hepatic toxicity or ActD - related blister formation . - pubmed
The primary endpoint was patient - reported shoulder - related pain . - pubmed
Although tumor immune checkpoint inhibitors therapy brings survival benefits to cancer patients , it also faces many challenges , such as the occurrence of immune - mediated hepatotoxicity . - pubmed
The Delayed Neuroprotective Effect of Methylene Blue in Experimental Rat Brain Trauma . - pubmed
However , on the 180th day after TBI , the magnetic resonance imaging scan of the animal brains did not show a significant reduction in the volume of the lesion in MB - treated animals . - pubmed
Recently , a pathogen has been identified as a novel coronavirus ( SARS - CoV-2 ) and found to trigger novel pneumonia ( COVID-19 ) in human beings and some other mammals . - pubmed
Methods : A retrospective interventional study that analyzes cases of congenital cataracts operated on a group of 14 children with Down syndrome , respectively on 26 eyes , was performed . - pubmed
The age of the children at the time of the surgery , the presence of associated ocular and systemic anomalies , the employed surgical technique , the frequency and the type of postoperative complications , were examined . - pubmed
Herein , we aim to summarize the relative efficacy and safety of all available diuretics used in the treatment of patients with HF . - pubmed
Diuretics are the main treatment of hypervolemia in HF patients . - pubmed
Spontaneously hypertensive rats ( SHRs ) and WKY rats were treated with VA deficiency ( VAD ) or normal ( VAN ) fodder for 20 weeks . - pubmed
Therapeutic Drug Level Monitoring of Teicoplanin in Korean Pediatric Patients with Normal versus Impaired Renal Function . - pubmed
Therefore , the aim of this study was to investigate the therapeutic drug level monitoring of teicoplanin in Korean pediatric patients , including those with impaired renal function . - pubmed
Distribution and characteristics of trough levels in patients with decreased renal function and those with bacteremia were also assessed . - pubmed
Median trough levels were higher in patients with decreased renal functions ( P < 0.001 ) . - pubmed
CONCLUSION : This study provides additive information on trough level monitoring of teicoplanin in children with impaired renal function and treatment effect in patients with gram - positive bacteremia . - pubmed
METHODS : HCC was induced in rats using a single dose of diethyl nitrosamine ( DENA ) ( 200 mg / kg , ip ) , followed by phenobarbital sodium ( 0.05 % ) in drinking water for 18 weeks . - pubmed
The history of ever having performed fellatio was associated with pharyngeal infection with N. - pubmed
There was , however , no association between pharyngeal infection with N. - pubmed
The authors evaluated 48 curves for the right and left kidney of 24 children free from any disorder of the uropoietic system , in whom radiorenography formed part of a general examination . - pubmed
The percentual differences in the curves were compared with the findings in a group of 64 children with cystopyelonephritis . - pubmed
Immunoselective loss of parental h antigens by somatic reduction in an H-2 a / H-2 b hybrid mouse leukemia . - pubmed
Spirolactones ( spironolactone , potassium canrenoate ) may produce secundary sexual effects such as gynecomastia in man and menstrual disturbances in women . - pubmed
Immune electron microscopy was performed on a serum pair and faeces from one of the patients with astrovirus . - pubmed
[ Correlation between immuno - morphological parameters of regional lymph nodes and the mortality of patients with stage I and II bronchial squamos cell carcinoma ] . - pubmed
, at least 16h before the earliest signs of thalidomide dysmelia have been reported in rabbits ( Vickers , ' 67 ) . - pubmed
Since the dorsal root ganglia form in rabbits on days 11 and 12 the changes evident at day 13 indicate that degeneration of neurons and axons may be a pathogenetic factor in thalidomide - induced peripheral deformities . - pubmed
In a 44 - year - old woman , a pancreatic pseudocyst was demonstrated on delayed images obtained up to 8 days after the intravenous administration of 0.250 mCi 75Se - selenomethionine . - pubmed
Prostaglandin release in canine acute haemorrhagic pancreatitis . - pubmed
Chromatographic analysis of the peritoneal exudate from the dogs with pancreatitis showed high levels of prostaglandin E - like material ( mean 43 ng / ml prostaglandin E2 equivalents ) . - pubmed
We examined twenty pregnant women with suspected rupture of membranes and twenty women with apparently intact membranes receiving routine prenatal care . - pubmed
A case report involving buspirone hydrochloride in the successful treatment of a patient with an atypical paraphilia and transvestic fetishism is presented . - pubmed
It is recommended in addition to echocardiography when cardiac tumors are suspected , especially in patients with tuberous sclerosis . - pubmed
Lactational [ correction of Lacational ] anovulation in rats and its dependency on progesterone . - pubmed
The same was true of 5 % permethrin cream ( 2.5 % in children below 5 years of age ) used in the treatment of scabies . - pubmed
Benzyl benzoate has an irritant potential , and lindane has been reported to exert CNS toxicity in a few anecdotal cases , in particular in small children or after repeated applications in patients with scabies crustosa , and permethrin was distinctly superior to both of these . - pubmed
This is documented by the results obtained in the treatment of 48 children and 56 adults suffering from scabies . - pubmed
Permethrin is recommended in scabies therapy in premature infants , small children , patients with seizures and neurological complications , in treatment failures with lindane entailing the need to repeat the therapy , in scabies crustosa and in pregnant women and nursing mothers . - pubmed
The techniques of Southern , Northern , and Western blotting along with in situ hybridization and immunohistochemistry are all applicable to the analysis of oncogene status in human solid tumors . - pubmed
Qualitative and quantitative alterations of these genes may be associated with the transformation and progression of human solid tumors . - pubmed
The existing follow - up standard for breast cancer patients has been reviewed by a representative trial involving 1,004 curatively treated patients , who underwent surgery between 1977 and 1987 . - pubmed
One hundred consecutive patients were prospectively studied to assess the clinical and biochemical features of symptomatic choledocholithiasis . - pubmed
Pain was the most frequent symptom of choledocholithiasis , observed in 75 % of the patients , but rarely occurred alone ( 12 % ) . - pubmed
These results indicate that , in patients with suggestive symptoms , choledocholithiasis is unlikely in the absence of biochemical abnormalities in the first three days following the onset of symptoms . - pubmed
Altered subsets of peripheral blood lymphocytes in patients with HTLV - I associated myelopathy ( HAM ) . - pubmed
We studied subsets of peripheral blood lymphocytes ( PBL ) from 12 patients with human T - lymphotropic virus type I ( HTLV - I ) associated myelopathy ( HAM ) . - pubmed
The effect of therapeutic irradiation upon B lymphocyte function was investigated in patients with various malignancies . - pubmed
Acetaminophen toxicosis : a potential model for acute liver failure in swine . - pubmed
Male crabs ( Chasmagnathus granulatus ) exhibited a defensive response ( DR ) to an electric shock ( 8 V , 50 Hz , 1 sec ) . - pubmed
High - dose continuous infusion folinic acid and bolus 5 - fluorouracil in patients with advanced colorectal cancer : a phase II study . - pubmed
Encouraging results have recently been reported for studies using folinic acid in combination with 5 - fluorouracil ( 5 - FU ) in the treatment of patients with gastrointestinal ( GI ) malignancies . - pubmed
Thirty - six patients with advanced colorectal cancer with unequivocal evidence of progression while treated with fluoropyrimidines were treated with a six - day continuous infusion of 500 mg / m2 / d of folinic acid initiated 24 hours before a five - day course of 5 - FU administered as an intravenous ( IV ) bolus of 370 mg / m2 / d. An initial dose of 250 mg / m2 / d of 5 - FU was used in patients previously treated with ionizing radiation and/or a nitrosourea . - pubmed
Tumor cells were found in the blood only at end - stage disease in a minority of animals . - pubmed
To elucidate possible mechanisms by which coenzyme Q10 enhances reoxygenation - induced recovery of cardiac contractile force after hypoxia , rabbit hearts were subjected to hypoxic perfusion for 20 min , followed by 45 min - reoxygenation with or without pretreatment with coenzyme Q10 . - pubmed
We performed cellular analysis of bronchoalveolar lavage fluids ( BALF ) from 20 patients in different stages of idiopathic pulmonary fibrosis ( IPF ) and compared the results with those from 16 controls and 10 sarcoidosis patients . - pubmed
Patients with IPF were divided into infiltrative and fibrotic groups as diagnosed by transbronchial lung biopsy and chest x - rays . - pubmed
Promotional effects of testosterone and high fat diet on the development of autochthonous prostate cancer in rats . - pubmed
Depots of testosterone implanted in Lobund - Wistar ( L - W ) rats , resulted in increased incidence of prostate adenocarcinomas ( PAs ) in the dorsal lateral lobe area . - pubmed
In testosterone - treated rats which had been fed the same diet plus 15 % corn oil , the prostate tumors were more numerous and they appeared earlier . - pubmed
Rats consuming the same feed containing 15 % corn oil ( no testosterone ) did not produce prostate tumors . - pubmed
Sixty - seven patients with idiopathic membranous glomerulonephritis ( iMGN ) were analyzed clinically . - pubmed
During the follow - up ( mean 6.7 years ) renal death occurred in four patients 12 - 151 ( mean 84.2 ) months after the diagnosis of iMGN . - pubmed
Patients with slight proteinuria never showed loss of renal function . - pubmed
The retrospective comparison of survival in patients who did ( N = 31 ) or did not ( N = 19 ) receive corticosteroids and/or immunosuppressive drugs for the treatment of NS revealed no evident difference at 5 or 10 years . - pubmed
This clinical analysis emphasizes the fairly favorable outcome of patients with iMGN . - pubmed
Mycoplasma meleagridis infection : development of lesions and distribution of infection in turkey embryos . - pubmed
[ Experimental contributions to the knowledge of the dermatitis pustulosa in sheep . - pubmed
Tumors and other lesions induced by murine sarcoma viruses . - pubmed
A new vaccine strain of feline panleukopenia virus grown in ferret cell culture . - pubmed
A comparative study of mouse foot pad inoculation of skin biopsy specimens from patients with lepromatous leprosy in San Francisco and Atlanta . - pubmed
We are reporting the case of a patient with this anomaly without concomitant arteriosclerotic involvement who was managed surgically . - pubmed
A 46 - year - old woman was seen with disabling angina of 8 months ' duration . - pubmed
Localization of the defect in skin diseases analyzed in the human skin graft - nude mouse model . - pubmed
In order to validate the use of the nude mouse human skin graft system in the analysis of skin defects , we have demonstrated that a systemic metabolic defect which involves the skin , namely essential fatty acid deficiency , can be differentiated from a defect residing primarily in the skin itself . - pubmed
In previous studies , lamellar ichthyosis was shown to be well maintained after prolonged periods of growth on nude athymic mice , indicating that the defect in this disease resides in the skin itself . - pubmed
Psoriasis is well maintained on the nude mouse - skin graft model . - pubmed
The epidermal hyperplasia and hyperproliferative epidermal cell kinetics of psoriasis are manifested in the grafts of active psoriasis maintained for prolonged periods on the nude mice , but the inflammatory component of psoriasis is absent . - pubmed
The medial fracture of the femur neck is mainly a fracture of the old man . - pubmed
For this analysis the concentration magnesium , copper and zinc was performed from 10 patients which got a medial fracture of the femur neck . - pubmed
There are no significant alterations in blood levels of magnesium , copper and zinc in patients with a medial fracture to normal population . - pubmed
We investigated the connection between the pulmonary hypertension and the lung function in the preoperative time of 176 patients undergoing an operation for prosthetic valve replacement in mitral and aortal position and in both of them . - pubmed
A patient was seen with secondary cluster headache whose acute pain responded promptly to sumatriptan . - pubmed
Backscattered electron imaging and energy - dispersive X - ray microanalysis studies of evidence for calcium salt heterogeneity in fifteen gallstones from an elderly human . - pubmed
PATIENTS : Patients ( N = 426 ; ages , & gt ; or = 65 years ) who were undergoing cataract surgery . - pubmed
CONCLUSIONS : Preoperative data can identify patients who are likely to have improvements in visual function after cataract surgery . - pubmed
[ Intraperitoneal perfusion of compound injection of salvia miltiorrhiza with dachengqi decoction in treating adhesive intestinal obstruction ] . - pubmed
The purpose of this study was to evaluate risk factors associated with peripheral vascular disease ( PVD ) in patients with non - insulin - dependent diabetes mellitus ( NIDDM ) . - pubmed
A group of 100 patients ( 50 men and 50 women ) aged 50 years or over with PVD and another group of 200 age - sex - matched patients ( 100 men and 100 women ) without PVD were studied . - pubmed
[ Effect of a new anticancer drug , docetaxel ( RP56976 ) , on human leukemia cell lines ] . - pubmed
The antitumor effect of a new derivative of taxol , docetaxel ( RP56976 ) , was examined in K562 human tumor system in vitro . - pubmed
The authors report results of an 8 - week , open trial of desipramine in 42 patients with DSM - III - R dysthymia with a concurrent diagnosis of major depression ( " double " depression ) and 33 patients with dysthymia who had no other depressive diagnosis ( " pure " dysthymia ) . - pubmed
Either complete or partial remission was achieved by 70 % of the patients with " pure " dysthymia . - pubmed
In patients with the clinical diagnosis of Alzheimer disease ( AD ) , we searched for systemic changes in components of the blood as a diagnostic tool . - pubmed
Combination chemotherapy for infections due to methicillin - resistant Staphylococcus aureus with combination therapy by cefuzonam and fosfomycin or minocycline in the urologic field . - pubmed
In this paper recent several reports were introduced and discussed on new opinion of precancerous conditions such as adenoma , intestinal metaplasia , gastric ulcer , remnant stomach and H. - pubmed
Gastric carcinogenesis for ulcer , remnant stomach and H. - pubmed
A sixty - year old woman had muscle pain of her extremities and stiffness in her fingers after unusual physical exertion . - pubmed
The rejection - free interval ( RFI ) following RATG treatment in group A was 21.6 + /- 10 days and 22 + /- 11 in group M. In group M , 3 of 27 patients ( 11 % ) had a rejection treatment - related infection ( 2 bacterial ; 1 viral ) versus 6 of the 42 patients of group A ( 14.2 % ; bacterial 1 , viral 5 ) . - pubmed
Children actuarial survival at 1 , 12 and 48 months was respectively 66 % , 60 % and 60 % versus 92 % , 86 % and 85 % , deaths occurring earlier in the urgent group . - pubmed
BACKGROUND : We investigated the incidence of axillary lymph node metastases in patients with T1a ( & lt ; or = 0.5 cm ) and T1b ( & gt ; 0.5 cm and & lt ; or = 1.0 cm ) breast cancers . - pubmed
METHODS : The charts of 2000 patients who underwent axillary lymph node dissection for breast cancer at our institution from 1989 to 1991 were reviewed . - pubmed
Of these , 81 patients had T1a and 166 had T1b primary breast cancers . - pubmed
Of those , 6 of 60 ( 10.0 % ) patients with T1a and 23 of 152 ( 15.1 % ) with T1b tumors had positive nodes . - pubmed
BACKGROUND : The authors previously showed that children require larger infusion rates of mivacurium than adults to maintain target twitch depression . - pubmed
Superfusion of ( 1S,3R )- ACPD produced a concentration - dependent ventral root depolarization in naive and hyperalgesic animals with no significant difference in EC50 values ( 55.5 + /- 6.36 microM and 51.0 + /- 5.76 microM , respectively , n = 4 ) . - pubmed
However , the amplitude of the maximum response was significantly enhanced by 23 % in hyperalgesic compared with naive animals . - pubmed
Altered activities of these substances in patients with risk factors for cardiovascular disease ( e.g. - pubmed
This review describes the role of NO in human health and disease and summarizes strategies currently being used to measure and improve endothelial dysfunction . - pubmed
Anesthetized , physiologically monitored male Wistar rats received 12.5 min of global forebrain ischemia by bilateral common carotid artery occlusions plus hemorrhagic hypotension to 45 mmHg . - pubmed
Hyperglycemic animals received dextrose ( 2.5 ml of a 25 % solution , intraperitoneally ) prior to ischemia ; this doubled the mean plasma glucose concentration to 296 mg/100 ml . - pubmed
The neocortex and striatum of NI rats showed only mild damage , while the majority of HI rats had extensive lesions , and several showed large cortical , striatal or thalamic infarcts . - pubmed
In addition , widespread cortical ischemic neuronal changes were evident in HI animals . - pubmed
By contrast , HI rats showed prominent peri- and intravascular polymorphonuclear and monocytic accumulation evident at 24 h ; frequent white cell thrombi in pial arterioles on day 3 ; and thickening of vascular endothelium , with foci of parenchymal rarefaction or microinfarction adjacent to occluded vessels . - pubmed
Prominent microglial activation , often along the course of penetrating blood vessels , was common in the striatum and neocortex of HI animals but was much less extensive in the NI group . - pubmed
Activated microglia in HI rats were typically hypertrophic and amoeboid . - pubmed
In the group of rats ( n = 10 ) operated on by using a straight IVC graft , graft congestion was seen and only 1 rat could survive over 1 day . - pubmed
Cutting edge : functional characterization of the effect of the C3H / HeJ defect in mice that lack an Lpsn gene : in vivo evidence for a dominant negative mutation . - pubmed
The impact of nutritional status on the prognoses of patients with advanced head and neck cancer . - pubmed
BACKGROUND : Malnutrition has been recognized as a poor prognostic indicator for cancer treatment - related morbidity and mortality in general , and it is reported to affect 30 - 50 % of all patients with head and neck cancer . - pubmed
In this study , the correlation of nutritional status with 3 - year survival was studied prospectively in 64 patients with T2 - T4 carcinomas of the head and neck who were treated surgically with curative intent ; the surgery was often followed by radiotherapy . - pubmed
CONCLUSIONS : Apart from the well - known prognostic parameters lymph node status ( T classification ) and status of surgical margins , preoperative weight loss and occurrence of major postoperative complications were also found to have a negative effect on the survival of male patients undergoing surgery for advanced head and neck cancer . - pubmed
ARCTIC : assessment of haemodynamic response in patients with congestive heart failure to telmisartan : a multicentre dose - ranging study in Canada . - pubmed
The beneficial effects of peroxynitrite on ischaemia - reperfusion arrhythmias in rat isolated hearts . - pubmed
These results suggest that ONOO (- ) at a low concentration may exert beneficial effects on ischaemia - reperfusion - induced arrhythmias in rat isolated hearts . - pubmed
About 25%-30 % of patients with non - small cell lung cancer can be resected with curative intent . - pubmed
However , systemic relapses occur in up to 70 % of these patients . - pubmed
[ Cotreatment of amyotrophic lateral sclerosis patients ] . - pubmed
Riluzole is a only drug which prolongs survival in amyotrophic lateral sclerosis ( ALS ) patients , however its effect is modest . - pubmed
We review the preclinical data supporting combination treatment for ALS and discuss the possible combination treatment in patients with ALS . - pubmed
Between 1982 and 1994 13 patients have needed surgery for priapism persisting after conservative measures using the technique described by Quackel . - pubmed
MATERIAL AND METHODS : 63 patients with osteogenesis imperfecta underwent a total of 186 primary intramedullary fixations with Bailey - Dubow rods during period 1984 - 1996 . - pubmed
Patients either suffered from knee - joint migration of the distal nail ( 3.9 % ) , proximal nail migration ( 7.9 % ) , detached T - pieces from the sleeve ( 7.9 % ) or chronical nail infection ( 1.0 % ) . - pubmed
Patients with diffuse large - cell type had better survival than patients with small noncleaved - cell type in Stage II high - grade lymphoma . - pubmed
Effect of ozone and nitrogen dioxide on the release of proinflammatory mediators from bronchial epithelial cells of nonatopic nonasthmatic subjects and atopic asthmatic patients in vitro . - pubmed
OBJECTIVE : to analyze the clinical features and associated morbidity in a group of patients with vascular dementia ( VD ) . - pubmed
METHODS : we retrospectively evaluated 25 patients with diagnosis of VD , based on the State of California Alzheimers Disease Diagnostic and Treatment Centers ( ADDTC ) criteria . - pubmed
IMPLICATIONS : This is a case report of a disk infection ( discitis ) caused by the bacteria , Streptococcus bovis after spinal anesthesia for cesarean delivery . - pubmed
Allergy to soy formula and to extensively hydrolyzed whey formula in infants with cow 's milk allergy : a prospective , randomized study with a follow - up to the age of 2 years . - pubmed
OBJECTIVES : We conducted a prospective , randomized study to evaluate the cumulative incidence of allergy or other adverse reactions to soy formula and to extensively hydrolyzed formula up to the age of 2 years in infants with confirmed cow 's milk allergy . - pubmed
STUDY DESIGN : Infants ( n = 170 ) with documented cow 's milk allergy were randomly assigned to receive either a soy formula or an extensively hydrolyzed formula . - pubmed
Soy formula can be recommended as a first - choice alternative for infants & gt;or=6 months of age with cow 's milk allergy . - pubmed
Uterine flushings were obtained under transvaginal ultrasonographic control from 132 women presenting for investigation and treatment of infertility . - pubmed
The overall frequency of these complications ( which involved the genito - urinary tract in over 75 % of cases ) regarded 5.3 % of all admission for HIV disease , with a clear prevalence of Enterococcus faecalis as the causative agent ( 86.5 % of episodes ) , and a proportionally elevated frequency of polymicrobial infection ( 45.9 % of cases ) . - pubmed
An advanced underlying HIV disease characterized by a concurrent , severe immunodeficiency , concomitant , prolonged neurological complications , hospitalization itself ( with prevalence of nosocomial infection ) , recourse to invasive diagnostic and/or therapeutic procedures , and prior administration of broad spectrum antimicrobial agents , all seem to support HIV - associated enterococcal disease ( mostly involving the genito - urinary tract ) . - pubmed
In nature , the AAL - toxin is the primary determinant of the Alternaria stem canker disease of tomato , thus linking apoptosis to this disease caused by Alternaria alternata f. sp . - pubmed
All patients presented maxillary ridge defects . - pubmed
Toxicity and carcinogenicity studies were conducted by administering turmeric oleoresin in feed to groups of male and female F344 / N rats and B6C3F1 mice for 13 weeks and 2 years . - pubmed
The final mean body weight of males receiving 50,000 ppm was 5 % lower than that of the controls . - pubmed
Dietary levels of 1,000 , 5,000,10,000 , 25,000 , or 50,000 ppm turmeric oleoresin were estimated to deliver average daily doses of 50 , 250 , 480 , 1,300 , or 2,600 mg / kg body weight to males and 60 , 300 , 550 , 1,450 , or 2,800 mg / kg to females . - pubmed
Hyperplasia of the mucosal epithelium was observed in the cecum and colon of male and female rats that received 50,000 ppm . - pubmed
There were no deaths attributed to turmeric oleoresin and the final mean body weight gains and final mean body weights of all exposed groups of male and female mice were similar to those of the controls . - pubmed
Dietary levels of 1,000 , 5,000,10,000 , 25,000 , or 50,000 ppm turmeric oleoresin were estimated to deliver average daily doses of 150 , 750 , 1,700 , 3,850 , or 7,700 mg / kg body weight to males and 200 , 1,000 , 1,800 , 4,700 or 9,300 mg / kg to females . - pubmed
The final mean body weights of all exposed male rats and female rats receiving 2,000 and 10,000 ppm were similar to those of the controls . - pubmed
The final mean body weights of male and female rats that received 50,000 ppm were slightly lower ( up to 10&percnt ;) than those of the controls throughout much of the study . - pubmed
Pathology Findings : Chemical - related nonneoplastic lesions occurred in the gastrointestinal tract of rats that received 50,000 ppm . - pubmed
Males receiving 50,000 ppm had increased incidences of ulcers , hyperplasia , and hyperkeratosis of the forestomach . - pubmed
Male and female rats that received 50,000 ppm had ulcers , chronic active inflammation , and hyperplasia of the cecum . - pubmed
Male and female rats that received 50,000 ppm and male rats that received 10,000 ppm had significantly increased incidences of sinus ectasia of the mesenteric Iymph node . - pubmed
The incidences of clitoral gland adenoma in all exposed groups of female rats were significantly increased . - pubmed
Clitoral gland carcinomas occurred in one control female and in four 2,000 ppm females , but not in females that received 10,000 or 50,000 ppm . - pubmed
The incidences of clitoral gland adenoma or carcinoma ( combined ) in all exposed groups of female rats were similar ( 6/50 , 16/48 , 15/47 , 16/49 ) and did not increase with exposure level . - pubmed
The incidence of clitoral gland hyperplasia was similar among exposed and control groups of female rats ( 7/50 , 5/48 , 4/47 , 7149 ) . - pubmed
The mean body weight of female mice receiving 50,000 ppm was slightly lower ( up to 12&percnt ;) than that of the controls from about week 25 . - pubmed
The final mean body weights of males that received 50,000 ppm and females that received 10,000 and 50,000 ppm were significantly lower than those of controls . - pubmed
The final mean body weights of other exposed groups of male and female mice were similar to those of the controls . - pubmed
Pathology Findings : The incidences of hepatocellular adenoma in male and female mice receiving 10,000 ppm , but not those in mice receiving 2,000 or 50,000 ppm , were significantly increased ( male : 25/50 , 28/50 , 35/50 , 30/50 ; female : 7/50 , 8/50 , 19/51 , 14/50 ) . - pubmed
The number of male and female mice in the 10,000 and 50,000 ppm groups with multiple hepatocellular neoplasms was significantly greater than that in the controls . - pubmed
In contrast to rats , there were no chemical - related nonneoplastic lesions of the gastrointestinal tract in mice . - pubmed
Three males that received 2,000 ppm and three males that received 10,000 ppm had carcinomas of the small intestine ; neoplasms of the small intestine were not observed in control males or in males that received 50,000 ppm . - pubmed
Female mice receiving 50,000 ppm had a significantly increased incidence of thyroid gland follicular cell hyperplasia . - pubmed
It induced small but significant increases in sister chromatid exchanges and chromosomal aberrations in cultured Chinese hamster ovary cells . - pubmed
There was equivocal evidence of carcinogenic activity of turmeric oleoresin in female F344 / N rats based on increased incidences of clitoral gland adenomas in the exposed groups . - pubmed
There was equivocal evidence of carcinogenic activity of turmeric oleoresin in male B6C3F1 mice based on a marginally increased incidence of hepatocellular adenoma at the 10,000 ppm level , and the occurrence of carcinomas of the small intestine in the 2,000 and 10,000 ppm groups . - pubmed
There was equivocal evidence of carcinogenic activity of turmeric oleoresin in female B6C3F1 mice based on an increased incidence of hepatocellular adenomas in the 10,000 ppm group . - pubmed
Turmeric oleoresin ingestion was also associated with increased incidences of ulcers , hyperplasia , and inflammation of the forestomach , cecum , and colon in male rats and of the cecum in female rats . - pubmed
In female mice , ingestion of diets containing turmeric oleoresin was also associated with an increased incidence of thyroid gland follicular cell hyperplasia . - pubmed
[ Variability of antigenic properties of drug - resistant strains of the Gonococcus ] . - pubmed
LIPID COMPONENTS OF BILE FROM CHOLINE DEFICIENT RATS . - pubmed
Fifty - two , 13 , and 9 MUD patients were treated with ATG in a total dose of 8 mg / kg , 6 mg / kg , and 4 mg / kg ( given from days -8 until -4 ) , respectively . - pubmed
Early age at EBV infection and lower socioeconomic status have been related to increased EBV - associated BL in developing countries . - pubmed
Our aim was to evaluate the clinicopathologic features and EBV association of 44 children with NHL from the state of Rio de Janeiro , situated in the southeast of Brazil . - pubmed
DNA from fresh tumor samples and from paraffin - embedded tissues of patients were analyzed by PCR , in which the first reaction included primers for an EBNA-2 common region while the nested reaction amplified the region discriminating between EBV types 1 and 2 in separate reactions . - pubmed
EBV was detected in 21 of 29 BLs ( 72 % ) , and type 1 virus infected the majority of EBV - positive BLs ( 18/21 ) . - pubmed
There was a trend for younger age in children with EBV - positive BL compared to EBV - negative BL ( median age 4 compared to 6 years , respectively ; p = 0.056 ) . - pubmed
In conclusion , our study suggests that early infection with EBV in the background of a low socioeconomic condition associated with other environmental factors could contribute to BL in Brazil . - pubmed
This alarming statistic is partly attributable to lifestyle , and partly due to the genetic factors that make humans highly susceptible to atherosclerotic vascular disease . - pubmed
PATIENTS AND METHODS : All 21 patients who had undergone the IQLO were analyzed for operation time , blood loss , length of hospitalization , intraoperative and postoperative complications , and radiographic abnormalities . - pubmed
Chemotherapeutic agents have been used for the treatment of patients with osteosarcoma ( OS ) . - pubmed
However , inherent or acquired resistance to these agents is a serious problem in the management of OS patients . - pubmed
The risk of iodine - induced thyrotoxicosis in euthyroid patients receiving iodine - containing contrast agents is known to be low , but data on this risk in patients with latent hyperthyroidism are scarce . - pubmed
In the 56 patients with TCTU less than 1 % , no case of iodine - induced hyperthyroidism occurred within 4 wk after CA . - pubmed
In the patients who received prophylactic drugs , two cases of mild thyrotoxicosis were observed . - pubmed
Furthermore , two major changes associated to aging : osteoporosis and sarcopenia , have been also linked to the development of frailty in elderly patients . - pubmed
In both cases vitamin D plays an important role since the low levels of this vitamin seen in senior people may be associated to a deficit in bone formation and muscle function . - pubmed
alpha - Lipoic acid induces apoptosis in human colon cancer cells by increasing mitochondrial respiration with a concomitant O2 -*-generation . - pubmed
We determined in HT-29 human colon cancer cells whether ALA is able to affect apoptosis , as an important parameter disregulated in tumour development . - pubmed
In conclusion , our study provides evidence that ALA and DHLA can effectively induce apoptosis in human colon cancer cells by a prooxidant mechanism that is initiated by an increased uptake of oxidizable substrates into mitochondria . - pubmed
Osteoporosis in its most common form affects the elderly ( both sexes ) and all racial groups of human beings . - pubmed
PIMT - deficient mice manifested neurodegenerative changes concomitant with the accumulation of L - isoaspartate in the brain . - pubmed
We discuss here the pathological implications of the formation of isoaspartate in damaged proteins during neurodegeneration in model mice and AD . - pubmed
Atorvastatin in patients with type 2 diabetes mellitus undergoing dialysis . - pubmed
OBJECTIVE : To investigate the effects of surgically induced weight loss on exercise capacity in patients with morbid obesity ( MO ) . - pubmed
After weight loss , obese patients performed each workload with lower oxygen consumption , heart rate , systolic arterial pressure , and ventilatory volume ( p & lt ; 0.001 ) . - pubmed
DISCUSSION : After surgically induced weight loss , MO patients markedly improved their exercise capacity . - pubmed
BACKGROUND : Noninvasive identification of culprit lesions has the potential to improve noninvasive risk stratification in patients with acute chest pain . - pubmed
METHODS : Thirty - seven patients with acute coronary syndrome ( ACS ) or stable angina underwent coronary 16 - slice MDCT and invasive selective angiography . - pubmed
Differences between culprit lesions in patients with ACS and stable lesions in patients with ACS or stable angina were determined . - pubmed
RESULTS : We analyzed 40 lesions with excellent image quality in 14 patients with ACS and 9 patients with stable angina . - pubmed
Culprit lesions in patients with ACS ( n = 14 ) had significantly greater plaque area and a higher remodeling index than both stable lesions in patients with ACS ( n = 13 ) and in patients with stable angina ( n = 13 ) ( 17.5 + /- 5.9 mm2 vs. 9.1 + /- 4.8 mm2 vs. 13.5 + /- 10.7 mm2 , p = 0.02 ; and 1.4 + /- 0.3 vs. 1.0 + /- 0.4 vs. 1.2 + /- 0.3 , p = 0.04 , respectively ) . - pubmed
The prevalence of non - calcified plaque was 100 % , 62 % , and 77 % , respectively , and the prevalence of calcified plaque was 71 % , 92 % , and 85 % , respectively , in culprit lesions in patients with ACS and in stable lesions in patients with ACS or stable angina . - pubmed
CONCLUSIONS : We introduce the concept of noninvasive detection and characterization of coronary atherosclerotic lesions in patients with ACS by MDCT . - pubmed
We show how guidelines formulated to advise travellers on appropriate chemoprophylaxis for areas of reported Plasmodium falciparum and Plasmodium vivax malaria risk can be used to generate crude spatial limits . - pubmed
Intracranial pressure monitoring in patients with acute liver failure : a questionable invasive surveillance . - pubmed
Coronary artery disease in patients with systemic lupus erythematosus . - pubmed
BACKGROUND : A 24 - year - old woman with an 11 - year history of systemic lupus erythematosus presented with exacerbation of chronic abdominal pain followed by substernal chest pain . - pubmed
Twenty macromastia patients were subjected to free - nipple - graft reduction mammoplasty in combination with inferior pedicled dermaglandular reduction mammaplasty of a total of 40 breasts with this technique between years 2000 and 2004 . - pubmed
In the present study , we evaluated the efficacy of HbV for improving stroke - related symptoms induced by middle cerebral artery ( MCA ) occlusion / reperfusion and an intra - internal carotid arterial injection of arachidonic acid ( AA ) in rats . - pubmed
was administered to rats immediately after the MCA occlusion , it reduced the cerebral infarct volumes of the cortex and total of the cortex plus sub - cortex significantly as compared with saline as a vehicle . - pubmed
Retrobulbar teratoma causing exophthalmos in a cat . - pubmed
A 3 - year female - neutered domestic shorthair cat presenting with exophthalmos and an ipsilateral subzygomatic soft tissue mass lesion is described . - pubmed
A retrobulbar location has not been previously reported in the cat and should be considered a rare cause of exophthalmos in this species . - pubmed
PATIENTS AND METHODS : Using strict inclusion criteria and a database of 1715 EVT patients , we identified ten idiopathic ruptured DCAAs ( 0.6 % ) over a 13 - year period ( 1993 - 2006 ) . - pubmed
The series comprised six males and four females with mean age of 64 years and solitary aneurysms located on posterior inferior cerebellar artery ( five patients ) , anterior inferior cerebellar artery ( three patients ) and superior cerebellar artery ( two patients ) . - pubmed
One patient died following a procedure - related re - bleeding and one patient required re - treatment after failed endosaccular packing . - pubmed
Focal cerebellar infarctions were seen on computed tomography images after EVT in three patients , only one of whom was symptomatic with transient dysmetria , which resolved completely during follow up . - pubmed
Based on the clinical symptoms observed in this patient , the broad differential diagnostic spectrum of hyperpigmentation of the nails is briefly reviewed here . - pubmed
In individuals who undergo hydroxycarbamide treatment , melanonychia might sometimes be seen as side effect and always has to be differentiated from subungual malignant melanoma . - pubmed
They were on triple immunosuppressive therapy and had serum creatinine level of less than 160micromol / L. Thirty - one patients ( 39.8 % ) were found to have blood cholesterol levels & gt ; 6.4 mmol / L. Significant positive correlation was found between hypercholesterolemia and cyclosporine blood levels above 200 ng / ml ( p< ; 0.0009 ) . - pubmed
There was no significant correlation between cholesterol blood level and the patient age , sex , presence of diabetes , prednisolone , dose , or treatment with C.-blockers and diuretics . - pubmed
In conclusion , hyper - cholesterolemia is common in stable renal transplant patients . - pubmed
The aim of this study was to investigate PPI deficit in relation to the dimensions of auditory hallucinations in patients with schizophrenia or schizoaffective disorder . - pubmed
METHOD : PPI of the acoustically elicited eye blink startle response was measured electromyographically in 62 patients with schizophrenia ( n=55 ) or schizoaffective disorder ( n=7 ) ( 26 of 62 with current auditory hallucinations ) and 22 healthy participants matched , on average , to age and sex of the patient group . - pubmed
Hearing voices with a high degree of negative content was associated with high mean startle amplitude in patients with current auditory hallucinations . - pubmed
CONCLUSIONS : Although auditory hallucinations in patients with schizophrenia are theorised to result from impaired monitoring of inner speech , the inability to consciously ignore them appears to be associated with a gating deficit . - pubmed
In this case series we present history , clinical manifestations , KOH smear , and histopathological findings of a series of four patients with crusted scabies . - pubmed
MATERIALS AND METHODS : MDCT - guided transthoracic needle biopsy ( TNB ) was performed on 84 patients ( 55 men and 29 women ; mean age 65 years ) with suspected lung neoplasm by using a spiral MDCT scanner with the simultaneous acquisition of six slices per rotation . - pubmed
METHODS : One hundred six patients with acute aneurysmal SAH were randomized to receive either peroral or intravenous nimodipine treatment . - pubmed
The patients were monitored for at least 10 days after bleeding in terms of delayed ischemic neurological deficits ( DINDs ) and with daily measurements of blood flow velocities in the middle cerebral arteries by using transcranial Doppler ultrasonography . - pubmed
Clinical outcome according to the Glasgow Outcome Scale was the same in both groups , and there was no difference in the number of patients with new infarctions on MR imaging . - pubmed
Hypertension is a common clinical disease and a major risk to human health . - pubmed
[ Changes in plasma hemostatic parameters under intravascular laser irradiation of blood in patients with community - acquired pneumonia ] . - pubmed
SUBJECTS AND METHODS : One hundred and forty patients aged 17 to 62 years ( mean 39.5 + /- 8.4 years ) with CAP were examined . - pubmed
CONCLUSION : ILIB is an effective method in correcting hemocoagulative disorders in patients with CAP . - pubmed
METHODS : Retrospective study of case - records of patients with intrabronchial mass lesions diagnosed by flexible bronchoscopy , bronchial washings and bronchial biopsy between January 2004 and June 2006 . - pubmed
Repeat traumatic brain injury in the juvenile rat is associated with increased axonal injury and cognitive impairments . - pubmed
Among the enormous population of head - injured children and young adults are a growing subpopulation who experience repeat traumatic brain injury ( RTBI ) . - pubmed
While several animal models have been proposed to study RTBI , they have been shown to either produce injuries too severe , were conducted in adults , involved craniotomy , or failed to show behavioral deficits . - pubmed
A closed head injury model for postnatal day 35 rats was established , and single and repeat TBI ( 1 - day interval ) were examined histologically for axonal injury and behaviorally by the novel object recognition ( NOR ) task . - pubmed
The results from the current study demonstrate that an experimental closed head injury in the rodent with low mortality rates and absence of gross pathology can produce measurable cognitive deficits in a juvenile age group . - pubmed
Over one in six persons with subclinical hypothyroidism progressed to overt thyroid dysfunction over the 5 - year period . - pubmed
Furthermore , the misidentification of nontuberculosis mycobacteria ( NTM ) in patients presumably suffering from tuberculosis results in additional human and health care costs . - pubmed
Discussed are the anatomic conditions leading to this syndrome in these two patients , the methodology for confirming the diagnosis , and the successful management by partial resection of the transverse processes compressing the vertebral arteries . - pubmed
Hyperplasia of airway smooth muscle cells ( ASMCs ) is a characteristic change of chronic asthma patients . - pubmed
METHODS : Twenty - seven asymptomatic adults with flat - arched foot posture were recruited to this study . - pubmed
To assess the possible risk factors for developing pain in normospermic adult varicocoele patients , 42 adult patients with left painful varicocoele ( group 1 ) and 35 age - matched patients with left painless varicocoele ( group 2 ) were recruited to this study . - pubmed
Tunnel vision and night blindness in a 52 - year - old man . - pubmed
METHODS : A retrospective analysis is performed : 20 consecutive patients with both lower extremity pain and low back pain , with low back counting for at least 30 % of the overall pain were implanted with a small profile plate type lead , S - Series ( SJM ) , via percutaneous approach . - pubmed
Patients were asked to rate their back and leg pain as well as their overall satisfaction and data on quality of life ( QOL ) on a ( 0 - 10 point ) visual analog scale ( VAS ) before and after implantation . - pubmed
Medication use , functional pain ( pain when bending forward , moving ) , and patient satisfaction scores also were collected . - pubmed
In 17 patients ( 85 % ) a clinically relevant reduction ( defined as reduction of 2 points or 30 % in VAS ) in back pain was seen , with a mean decrease of 4.3 points ( 2.0 - 10.0 ) or 52 % ( 22 - 100 ) . - pubmed
Only three patients had no reduction in back pain , although they had reduction of their pain in the lower extremities . - pubmed
CONCLUSION : Percutaneous implantation of the S - Series plate electrodes using a 10 gauge epidural needle combines the advantages of a minimal invasive technique with the possibility to cover the back area supplementing leg coverage in 85 % of the failed back surgery syndrome patients . - pubmed
There has been significant progress towards guinea worm eradication , and the control of leprosy and human African trypanosomiasis . - pubmed
Extract from Dioscorea batatas ameliorates insulin resistance in mice fed a high - fat diet . - pubmed
The aim of this study was to investigate whether Dioscorea batatas ( DB ) extract attenuates high - fat diet ( HFD)-induced insulin resistance in the visceral adipose tissues of mice , and by what mechanism(s ) . - pubmed
Mice were fed a HFD for 4 weeks to induce the early development of insulin resistance . - pubmed
The DB extract was administered to mice fed a HFD by oral gavage at a dose of 100 mg / kg body weight daily for 7 weeks . - pubmed
PATIENTS : From March 2009 to January 2011 , 26 consecutive patients ( 19 men and 7 women ) with a median age of 63 ( range , 49 - 79 ) years with hepatocellular carcinoma were recruited . - pubmed
Five ( 19 % ) of the patients had recurrent hepatocellular carcinoma after previous treatment . - pubmed
Recurrent tumours were noted in 11 ( 42 % ) of the patients ( 5 were local , 2 were remote , and 4 were multifocal ) after a median follow - up of 14 ( range , 4 - 26 ) months . - pubmed
The failure rate for local disease control was 23 % , and was 14 % if patients with recurrent hepatocellular carcinoma were excluded . - pubmed
This study aimed at assessing the efficacy and safety of biweekly oxaliplatin in combination with continuous infusional 5 - fluorouracil and leucovorin ( modified FOLFOX regimen ) in patients with advanced small bowel adenocarcinoma ( SBA ) . - pubmed
All patients were evaluable for efficacy and toxicity . - pubmed
Grade 3 toxicities included neutropenia ( 12.1 % ) , thrombocytopenia ( 3.0 % ) , nausea ( 6.1 % ) , vomiting ( 3.0 % ) , diarrhea ( 3.0 % ) , peripheral neuropathy ( 9.1 % ) , and fatigue ( 3.0 % ) , and grade 4 toxicities occurred in none of the patients . - pubmed
The modified FOLFOX regimen is highly active and well tolerated as first - line chemotherapy for advanced SBA patients . - pubmed
METHODS : We retrospectively reviewed stroke patients with sMLI or SLI in a consecutively collected stroke registry with a predefined long - term clinical follow - up . - pubmed
RESULTS : Of the 548 acute ischemic stroke patients , sMLI was found in 23 ( 13.5 % ) and SLI in 148 ( 86.5 % ) . - pubmed
Preclinical studies with non - replicating herpes simplex virus ( HSV)-based vectors injected into the skin to transduce neurons in the dorsal root ganglion have demonstrated efficacy in reducing - pain related behaviors in animal models of inflammatory pain , neuropathic pain , and pain caused by cancer , and in preventing progression of sensory neuropathy caused by toxins , chemotherapeutic drugs or resulting from diabetes . - pubmed
Successful completion of the first phase 1 clinical trial of HSV - mediated gene transfer in patients with intractable pain from cancer has set the stage for further clinical trials of this approach . - pubmed
In our report , we explored the pharmacokinetic , pharmacodynamic , and antitumor properties of MLN0905 in DLBCL xenograft models grown in mice . - pubmed
The antitumor activity of MLN0905 was evaluated in three human subcutaneous DLBCL xenograft models , OCI LY-10 , OCI LY-19 , and PHTX-22L ( primary lymphoma ) . - pubmed
The antitumor activity of MLN0905 was also evaluated in a disseminated xenograft ( OCI LY-19 ) model to better mimic human DLBCL disease . - pubmed
A 62 - year - old man was referred to our center for fracture of the left clavicle because of a fall , and he had a sudden seizure during admission . - pubmed
EBV - encoded RNA was negative for tumor cells . - pubmed
During the daytime , we interrupted the sedatives and analgesics unless the patient complained of discomfort . - pubmed
CONCLUSIONS : In mechanically ventilated patients , nighttime infusion of dexmedetomidine preserved the day - night cycle of sleep but induced severely disturbed sleep architecture without evidence of SWS or REM sleep . - pubmed
RESULTS : Of 41 children enrolled , relative AVP deficiency was present in 13 ( 32 % ) . - pubmed
Initial combination therapy reduces the risk of cardiovascular events in hypertensive patients : a matched cohort study . - pubmed
AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model . - pubmed
Mice treated with an optimized 5 - day induction protocol showed transient weight loss , short - term reduction of peripheral blood cell and platelet counts , and slight anemia . - pubmed
AML cells showed significantly increased sensitivity to doxorubicin - containing therapy compared with murine BM cells . - pubmed
Although early treatment could result in some cures , mice with significant leukemia grafts were not cured by using induction therapy alone . - pubmed
We report a case of a life - long non - smoker , 54 years old woman who presented these symptoms associated with bronchiectasis secondary to recurrent inhalation pneumonia , hypercapnic respiratory failure , and central sleep apnea ( CSA).CSA was first unsuccessfully treated with nocturnal c - PAP . - pubmed
We suggest that in patients with type I ACM the presence of pulmonary manifestations aggravating other respiratory disturbances including sleep disordered breathing ( SDB ) should be actively investigated . - pubmed
These results show that infection with arg(- ) L. - pubmed
A visual analog scale ( VAS ) was used to quantify the amount of pain , swelling , and bleeding in the patients . - pubmed
In addition to maintaining the metabolic demands of the individual in the short term , levels of energy intake must also maintain and defend body weight over longer periods . - pubmed
Early and late outcomes of hybrid endovascular and open repair procedures in patients with peripheral arterial disease . - pubmed
PATIENTS AND METHODS : Consecutive patients with multilevel arterial disease who underwent single session hybrid procedures were analyzed depending on the type of ischaemia and the type of revascularization . - pubmed
Regional and overall aortic function in nondiabetic individuals with insulin resistance and normal glucose tolerance . - pubmed
OBJECTIVE : The objective of the study was to define the overall and regional aortic function as well as the changes of aortic function over time in nondiabetic individuals with insulin resistance and a normal oral glucose tolerance test ( OGTT ) . - pubmed
All infections occurred in patients who had received patellar resurfacing . - pubmed
Effects of dutasteride on lower urinary tract symptoms and general health in men with benign prostatic hypertroplasia and hypogonadism : a prospective study . - pubmed
INTRODUCTION : We investigated the effects of the relative increase in testosterone by dutasteride administration in patients with benign prostatic hyperplasia and hypogonadism on urinary symptoms or androgen - responsive general health . - pubmed
All patients responded to the questionnaires : International prostatic symptom score ( IPSS ) , Overactive Bladder Symptom score ( OABSS ) . - pubmed
We present a case report of a 74 - year old female patient with the clinical diagnosis of transient ischemic attack ( TIA ) in the vertebro - basilar ( VB ) circulation , in whom we found bilateral variation of the extracranial section of vertebral arteries on ultrasound , on the left side to the extent of kinking . - pubmed
Screening for this innate response predicted accurately in which mice recurrence would occur . - pubmed
[ Relationship between residual milk and clinical mastitis in dairy cattle ] . - pubmed
Mastitis in cattle is an infection of the mammary gland caused by infection , toxins and/or trauma . - pubmed
We aim to examine the association between rapid eye movement ( REM ) AHI and QOL scores in children with sleep - disordered breathing ( SDB ) . - pubmed
SUBJECTS AND METHODS : Children between 3 and 16 years of age with suspected SDB who were undergoing PSG were eligible . - pubmed
The content of oleanolic and ursolic acid in the extracts were determined , and different samples were screened for cellular cytotoxicity and virus inhibition using a HCV cell culture infection system . - pubmed
METHODS : Fifty - one patients with CLBP and 56 patients with CNP participated . - pubmed
Reply : Endometrial injury and reproductive outcomes : there 's more to this story than meets the horse 's blind eye . - pubmed
In addition , a number of studies utilizing optogenetic strategies or transgenic mouse lines have begun to examine specific central amygdala neurocircuit dynamics and neuronal subpopulations to better understand overall central amygdala neurocircuitry and the role of neuronal subtypes in mediating anxiety - like behaviors . - pubmed
Though the initial brain imaging showed extensive involvement of the white matter with multiple haemorrhagic foci , the patient improved spontaneously with no specific therapy . - pubmed
METHODS : Sixty - eight Candida isolates ( 37 albicans and 31 non - albicans isolates ) recovered from corneal scrapings submitted to rule out microbial keratitis , during the years 2005 to 2011 , at the Bascom Palmer Eye Institute , were examined in this study . - pubmed
Mouse models are common tools for examining post - traumatic osteoarthritis ( OA ) , which involves cartilage deterioration following injury or stress . - pubmed
One challenge to current mouse models is longitudinal monitoring of the cartilage deterioration in vivo in the same mouse during an experiment . - pubmed
Future studies may use this reporter mouse to advance basic and preclinical studies of murine experimental OA with applications in synovial joint biology , disease pathogenesis , and drug delivery . - pubmed
From October 2013 to date , approximately 1,000 outbreaks of porcine epidemic diarrhoea virus ( PEDV ) have occurred in Japan . - pubmed
Phylogenetic analysis indicated that the Tottori2 PEDV strain might have been derived from the current PEDV strains circulating in domestic pigs . - pubmed
Moreover , the Tottori2 PEDV strain was successfully isolated in Vero cells by serial passage . - pubmed
The incorporation of the PSAD into risk assessments might provide additional prognostic information and identify some patients in whom active surveillance would be appropriate in patients with IRPCa . - pubmed
HIV / AIDS . - pubmed
OBJECTIVE : Analyzing the quality of sleep of hypertensive patients registered in the national registration system and monitoring of hypertensive patients . - pubmed
RESULTS : The prevalence of poor sleep quality among respondents ( 156 hypertensive patients ) and high rates of using medication for sleeping ( 106 hypertensive patients ) was observed . - pubmed
BACKGROUND AND OBJECTIVES : Insulin resistance has been associated with cardiovascular disease in peritoneal dialysis patients . - pubmed
Patients were categorized according to dialysate to plasma creatinine ratio at 4 hours , 3.86 % peritoneal equilibration test , and obesity parameters . - pubmed
RESULTS : Obesity was present in 49 % of patients according to rel . - pubmed
A total of 18 patients ( 35.3 % ) who had insulin resistance presented with higher LAR and rel . - pubmed
CONCLUSIONS : Insulin resistance in nondiabetic peritoneal dialysis patients is associated with obesity and LAR independent of glucose absorption and small - solute transport status . - pubmed
Compound 13d , having good in vitro ADME profile and moderate oral bioavailability in mice , showed potent anti - inflammatory activity against hapten - induced contact hypersensitivity reaction in mice following topical and oral administration . - pubmed
MATERIALS AND METHODS : We conducted a prospective randomized study for a period of 2 years from September 2007 to August 2009 in 109 untreated patients of squamous cell carcinoma of head and neck with histologically confirmed diagnosis and no evidence of distant metastasis . - pubmed
CONCLUSION : Use of 6 fractions per week instead of 5 fractions per week is feasible , tolerable , and results in a better outcome in the patients of head and neck cancers . - pubmed
We conclude that liver resection may improve the short- and long - term survival of carefully selected intermediate HCC patients , and the procedure may be safely performed in the management of intermediate HCC . - pubmed
The effect of 1 mg folic acid supplementation on clinical outcomes in female migraine with aura patients . - pubmed
We have previously provided evidence that reduction of homocysteine with a vitamin supplementation can reduce the occurrence of migraine in women . - pubmed
METHODS : This was a 6 month randomised , double blinded placebo controlled trial of daily vitamin supplementation containing 1 mg of folic acid , 25 mg of Vitamin B6 and Vitamin B12 , on reduction of homocysteine and the occurrence of migraine in 300 female patients diagnosed with migraine with aura . - pubmed
The treatment group did not show a significant decrease in the percentage of participants with high migraine disability , severity or frequency at the end of the 6 month intervention ( P & gt ; 0.1 ) . - pubmed
Nineteen percentage of children treated with ondansetron continued vomiting after the administration of the therapy vs 93 % of children who received traditional therapy ( P & lt ; 0.05 , relative risk = 0.2 ) . - pubmed
Moreover , we asked whether increased accumulation of oxysterols characterizes the adipose cells of obese patients with type 2 diabetes ( T2D ) ( OBT2D ) compared with lean , nondiabetic controls ( CTRLs ) . - pubmed
Co - administration of thioperamide and oxytocin significantly amplified hypophagic effect of oxytocin in chickens ( P & lt ; 0.001 ) . - pubmed
In addition , ICI 118,551 attenuated hypophagic effect of oxytocin ( P & lt ; 0.001 ) ; while famotidine , prazosin , yohimbine , metoprolol and SR59230R had no effect on oxytocin- induced food intake in FD3 broiler chickens . - pubmed
In cases of cyst fenestrations postoperatively , the cyst volume was significantly reduced in all patients by mean of 47 % . - pubmed
METHODS : In 2009 , a retrospective analysis was performed at one tertiary referral center for 953 patients diagnosed with tuberculosis . - pubmed
Long - term outcomes of infliximab treatment and predictors of response in 195 patients with ulcerative colitis : a hospital - based cohort study from Korea . - pubmed
BACKGROUND : Large - scale studies regarding the long - term efficacy of infliximab ( IFX ) treatment in non - Caucasian patients with ulcerative colitis ( UC ) are lacking . - pubmed
STUDY : We analyzed the long - term outcomes of IFX in 195 Korean UC patients who received scheduled IFX treatments at Asan Medical Center . - pubmed
Multiple Subpial Transections for Medically Refractory Epilepsy : A Disaggregated Review of Patient - Level Data . - pubmed
Data regarding seizure outcome , patient demographics , seizure type , surgery type , and complications were extracted and analyzed . - pubmed
Complications were frequent , with transient mono- or hemiparesis affecting 19.8 % of patients , transient dysphasia 12.3 % , and permanent paresis or dysphasia in 6.6 % and 1.9 % of patients , respectively . - pubmed
Acute kidney injury ( AKI ) is a common and serious condition frequently encountered in hospitalized patients . - pubmed
Differences in Neurocognitive Impairment Among HIV - Infected Latinos in the United States . - pubmed
OBJECTIVES : Human immunodeficiency virus ( HIV ) disproportionately affects Hispanics / Latinos in the United States , yet little is known about neurocognitive impairment ( NCI ) in this group . - pubmed
METHODS : We prospectively studied 286 patients with AIS who were admitted within 24 h after the onset of symptoms . - pubmed
Evaluation of Serum Symmetric Dimethylarginine Concentration as a Marker for Masked Chronic Kidney Disease in Cats With Hyperthyroidism . - pubmed
Currently , there is no clinical test that can reliably predict which hyperthyroid cats have concurrent azotemic CKD that will become apparent after treatment of the hyperthyroidism . - pubmed
OBJECTIVES : To investigate serum symmetric dimethylarginine ( SDMA ) concentration as a potential marker of masked azotemia in untreated hyperthyroid cats . - pubmed
ANIMALS : Two hundred and sixty - two hyperthyroid cats and 206 aged - matched , clinically normal cats . - pubmed
RESULTS : No hyperthyroid cats were azotemic before treatment , but 42 ( 16 % ) became azotemic when rechecked at 4 - 8 months ( median , 6 months ) after 131 I treatment ; of these , 14 had high SDMA concentrations before treatment . - pubmed
As a diagnostic test for pre - azotemic ( masked ) CKD in untreated hyperthyroid cats , SDMA showed a sensitivity of 33.3 % and specificity of 97.7 % . - pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : Finding a high serum SDMA concentration in a hyperthyroid cat can help predict development of azotemia after treatment . - pubmed
The test has high diagnostic test specificity ( few false - positive results ) but relatively low sensitivity ( fails to predict azotemia in most hyperthyroid cats ) . - pubmed
Cheese - derived SFA and individual SFA that are commonly found in cheese , were significantly related to lower T2D risks . - pubmed
Due to the increased detection of O113 strains and their relationship with clinical cases , which emphasizes the importance of this serogroup as an emerging pathogen , our aim was to determine the characteristics of STEC O113 : H21 strains circulating in bovine cattle and retail meat from Argentina . - pubmed
IMPORTANCE The high - risk human papillomaviruses ( HPVs ) are the etiological cause of cervical cancer and the most common sexually transmitted infection . - pubmed
While the majority of infections may be asymptomatic or cause only benign lesions , persistent infection with the oncogenic high - risk HPV types may lead to serious diseases , such as cervical cancer , anogenital carcinoma , or head and neck oropharyngeal squamous cell carcinoma . - pubmed
A case study based on Orthopoxviruses ( Variola , Monkeypox , and Ectromelia viruses ) demonstrates a considerable increase in the fluorescence signal ( up to 100 - fold ) when several oligonucleotide probes are printed to one spot . - pubmed
A cerebral ischemic / reperfusional ( CI / R ) injury model in mice was implemented to elucidate the neuronal protective mechanism(s ) of P7C3 . - pubmed
Anticancer studies demonstrated the in vitro cytotoxicity value of Cu - NPLs against tested human colon cancer Caco-2 cells , human hepatic cancer HepG2 cells and human breast cancer Mcf-7 cells . - pubmed
To conclude , Cu - NPLs are promising in electronic devices and they possess a potential anticancer application for some human cancer therapy as well . - pubmed
We previously isolated a monocrotophos - degrading strain Starkeya sp . - pubmed
METHODS : We used 2191 NPC patients as a training set and 414 patients separately as an independent , external validation cohort . - pubmed
Massive amounts of medical and health resources have been devoted to patients with osteoporosis and osteoporosis - related fractures . - pubmed
Due to the emerging resistance by the parasites and mosquitoes for the current medications and insecticides , respectively , the malaria free human world can be attained only by the novel design and development of new anti - malarial drugs . - pubmed
miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer ' s Patients . - pubmed
ROC analysis indicated that measurement of miR-132 - 3p in neurally - derived plasma EVs showed good sensitivity and specificity to diagnose AD , but did not effectively separate individuals with AD - MCI from controls . - pubmed
Moreover , when we measured the levels of a related miRNA , miR-212 , we found that this miRNA was also decreased in neural EVs from AD patients compared to controls . - pubmed
Regional and temporal miRNAs expression profile in a transgenic mouse model of tauopathy : implication for its pathogenesis . - pubmed
In the current paper , we assessed the miRNA expression profile at different age time points and brain regions in a relevant mouse model of human tauopathy , the hTau mice , in relationship with the development of behavioral deficits and tau neuropathology . - pubmed
The expression of platelet - derived growth factor receptor alpha - positive cells in the stenotic tissue of ureteropelvic junction obstruction in children : . - pubmed
Purpose : The patient - reported outcome measure ( PROM)-based evaluation in lumbar degenerative disc disease ( DDD ) is today 's gold standard but has limitations . - pubmed
Patients with LEMD had slightly higher disability ( ODI 52.8 vs. 48.2 , p=0.025 ; RMDI 12.6 vs. 11.3 , p=0.034 ) but similar pain and hrQoL scores . - pubmed
OFI T - scores were significantly higher in patients with LEMD ( 144.2 vs. 124.3 , p=0.006 ) . - pubmed
The draft genomes of three fungal clinical isolates of Madurella mycetomatis from patients with mycetoma are presented . - pubmed
A middle - aged woman was hospitalised for generalised , painful skin lesions 6 weeks after a successful double - lung transplant . - pubmed
Patients were followed - up until the delivery and final outcomes of pregnancy were recorded in terms of preterm delivery and SGA births . - pubmed
Here , we describe a case in which a patient developed extensive anal epithelial proliferations resembling condylomata acuminata , after starting vemurafenib treatment . - pubmed
OBJECTIVE : We aim to conduct a systematic review and meta - analysis of observational studies on the association between LAN exposure and risk of obesity in human subjects . - pubmed
Suprapubic cystostomy during renal transplantation in a patient with a urethral stricture after hypospadias surgery : A case report . - pubmed
Conclusion : A cystostomy may be one strategy for renal transplantation patients with a urethral stricture . - pubmed
As - sessment of the antimicrobial activity of the conjugate revealed that attachment of the salmochelin mimic resulted in decreased potency , compared to ciprofloxacin , against two Escherichia coli strains , K12 and Nissle 1917 , in both iron - replete and deplete conditions . - pubmed
Collectively , our results suggest that telomere shortening could represent a mechanism that moderates the proliferative capacity of human hippocampal progenitors , which may subsequently impact on human cognitive function and psychiatric disorder pathophysiology . - pubmed
Questionnaire responses from the pig keepers in this area highlighted the need to implement basic biosecurity measures in smallholder pig keepers to prevent outbreaks of ASF in South Africa . - pubmed
Background : The study was aimed to evaluate the safety and efficacy of fentanyl and pethidine on the sedative quality of patients who underwent phacoemulsification cataract surgery with Propofol . - pubmed
Demographic characteristics , hemodynamic parameters before , during , and after the operation , sedation and pain scores , and patients ' and surgeons ' satisfaction scores were compared in the two studied groups . - pubmed
METHODS : We conducted a prospective case - control study in an inception cohort of 552 patients ( 328 IBD , 224 non - IBD ) , profiling proteins recruited across 6 centres . - pubmed
These findings have profound implications for the development of murine models of human inflammatory disorders such as infection and sepsis . - pubmed
What are the risk factors for surgical site infection in HIV positive patients receiving open reduction and internal fixation of traumatic limb fractures ? - pubmed
We questioned ( 1 ) what is the proportion with SSI in HIV positive patients receiving open reduction and internal fixation ( ORIF ) of traumatic limb fractures ; ( 2 ) what are the independent risk factors for SSI of HIV positive patients with traumatic limb fractures who received ORIF . - pubmed
Data of HIV positive adult patients with traumatic limb fractures treated by ORIF were extracted from the electronic medical records , including the demographic information , characteristics of fractures , treatment - related variables and indexes of laboratory examination . - pubmed
RESULTS : A total of 26 patients developed SSI in this study , the overall proportion was 10.6 % ( 95 % CI=7.2%-15.3 % ) . - pubmed
CONCLUSION : We recommend that orthopedic surgeons assess immunosuppression and nutritional status of HIV positive patients rigorously and optimize the perioperative strategy of supplementary to reduce the risk of SSI . - pubmed
Methods : Cell function tests were performed to observe the inhibitory effect of cynaropicrin on human CRC cells ( RKO , HCT116 , and DLD-1 ) . - pubmed
Results : Cynaropicrin significantly reduced the survival ability of human CRC cells and promoted apoptosis in a dose - dependent manner . - pubmed
PARTICIPANTS : Adults with and without TSCI . - pubmed
Characteristics of the maternal lymphoid response of mice to paternal strain antigens induced by homologous pregnancy . - pubmed
Mice mated with H-2 incompatible males were shown to have an increased frequency of specific allocluster - forming spleen cells to paternal strain erythrocytes . - pubmed
Peripheral blood leukocytes ( PBL ) from patients with rheumatoid arthritis ( RA ) and from control subjects were exposed to rheumatoid and osteoarthritic synovial membrane extracts . - pubmed
Pulmonary angiography was performed in 125 patients with suspected pulmonary embolism . - pubmed
Balloon - occlusion angiography improved image quality and contributed substantially to the radiographic diagnosis of pulmonary embolism in most patients . - pubmed
[ Long - term follow - up of patients with disorders of intraventricular conduction in the acute phase of myocardial infarct ] . - pubmed
A light microscopic study of bovine peripheral nerve sheath tumours . - pubmed
Peripheral nerve sheath tumours from 66 cattle were classified as schwannomas and neurofibromas . - pubmed
Bovine neurofibromatous tissue probably represents a dysplasia whilst bovine schwannomas are true neoplastic growths . - pubmed
Bovine schwannomas probably develop from neurofibromatous nerve and the two entities may represent parts of a single pathological condition . - pubmed
Hearing loss in renal dialysis and renal transplant patients occurs quite frequently . - pubmed
Sepsis was diagnosed in 18 patients , that made 1.7 per cent to a total number of observations . - pubmed
Among these septic patients 8 patients died . - pubmed
Protooncogene activation in spontaneously occurring and chemically induced rodent and human lung tumors . - pubmed
Characteristics and kinetics of subzero chilling injury in Drosophila embryos . - pubmed
and in the rat chronic gastric fistula model . - pubmed
The new anthracycline analogue , 4 '- iodo-4 '- deoxydoxorubicin ( I - DOX ) , was administered at 70 mg / m2 as first chemotherapy in 61 patients with advanced NSCL ( 19 ) , colon ( 20 ) and breast cancers ( 22 ) . - pubmed
Partial responses were observed in 6 % of the patients with NSCL , in 5.5 % of those with colon and in 10 % of those with breast cancers . - pubmed
The main toxicity was a selective granulocytopenia characterized by a duration of about 1 week , and a high inter - patient variability . - pubmed
Although the biological function of the F alloantigen is unknown , the immune response to F has been extensively studied as a murine model of tolerance and autoimmunity . - pubmed
The immune response to the allotypic form is restricted to mouse strains of I - Ak. - pubmed
The Epstein - Barr virus ( EBV ) is associated with distinct forms of human lymphoid malignancies , including the endemic ( eBL ) and sporadic forms of Burkitt ' s lymphoma ( sBL ) and acquired immunodeficiency syndrome - associated non - Hodgkin lymphoma ( AIDS - NHL ) . - pubmed
However , whether EBV has a pathogenetic role in these tumors or is a passenger virus has not been conclusively demonstrated . - pubmed
Toward this end we analyzed the structure of the heterogeneous genomic termini of EBV as markers of clonal infection in a panel of eBL ( 11 cases ) , sBL ( 9 cases ) , and AIDS - NHL ( 10 cases ) biopsies . - pubmed
A 49 - year - old man with aseptic meningitis and multiple cranial neuropathies . - pubmed
Myocarditis accompanies sublethal mouse cytomegalovirus ( MCMV ) infection in susceptible BALB / c mice and persists beyond the acute phase of infection , in the absence of demonstrable virus antigen but in the continuing presence of autoantibodies to cardiac muscle . - pubmed
Increasing the virus dose given to C57BL/10 mice resulted in slight increases in titres of anti - myosin antibody ; however , the peak antibody titres did not approach those of BALB / c mice and persisting myocarditis did not develop . - pubmed
Clinical validity of a normal perfusion lung scan in patients with suspected pulmonary embolism . - pubmed
The objective of this study was to test the safety of withholding anticoagulant therapy in patients with clinically suspected pulmonary embolism who have normal perfusion lung scans , regardless of the clinical manifestations . - pubmed
Anticoagulant therapy was withheld or withdrawn in 515 consecutive patients except in patients in whom deep - vein thrombosis was detected . - pubmed
Only three of the 515 patients had symptomatic venous thromboembolism on follow - up . - pubmed
It is safe to withhold anticoagulant therapy in patients with suspected pulmonary embolism and normal perfusion scans , regardless of the clinical manifestations . - pubmed
To determine the potential utility of antigen - specific immune complex analysis , we developed a competitive enzyme - linked immunosorbent assay utilizing polyclonal human antibody to detect tumor - associated antigen - specific immune complexes . - pubmed
Sera from 10 normal volunteers and 19 patients with recurrent melanoma were studied . - pubmed
Patients with recurrent melanoma had a mean + /- SD percent inhibition of 27.6 % + /- 29.8 % in contrast to normal individuals with a mean value of 8.4 % + /- 17.8 % . - pubmed
Utilizing MAb JSI , we developed a " sandwich " enzyme - linked immunosorbent assay and studied sera from 45 normal volunteers and 44 patients with cancer with recurrent melanoma . - pubmed
The mean + /- SD percent maximum binding for normal subjects was 4.9 % + /- 7.7 % in contrast to sera from patients with melanoma who had a mean of 38.3 % + /- 33.3 % . - pubmed
Serial analysis of four patients with melanoma with tumor - associated antigen - specific immune complexes demonstrated the presence of tumor - associated antigen - specific immune complexes up to 12 years prior to clinical recurrence . - pubmed
The effect of repeated external cephalic version , performed at between 33 and 40 weeks gestation , on presentation at delivery was studied in a randomized controlled trial comprising 180 pregnant women with breech presentation . - pubmed
Cerebral haemorrhage in a pregnant woman with a multiple endocrine neoplasia syndrome ( type 2A or Sipple ' s syndrome ) . - pubmed
We present the case history of a 30 - yr - old woman who suffered a cerebral haemorrhage toward the end of pregnancy ( at 35 wk ) . - pubmed
Effects of phenobarbital and secondary bile acids on liver , gallbladder , and pancreas carcinogenesis initiated by N - nitrosobis ( 2 - hydroxypropyl ) amine in hamsters . - pubmed
[ The survival rate of primary molar fillings in schoolchildren in relation to increase in caries and caries prevention ] . - pubmed
Malachite green therapy of proliferative kidney disease in rainbow trout : field trials . - pubmed
The results of a series of experiments to investigate the use of the arylmethane dye , malachite green , for the control of proliferative kidney disease in rainbow trout ( Salmo gairdneri Richardson ) are described . - pubmed
The epidemiology of diplostomiasis in farmed rainbow trout from north - east Scotland . - pubmed
Experiments using caged fish indicated that diplostomiasis was confined to certain areas of the farm only and that the infection rate of rainbow trout with D. - pubmed
The results of the study indicated that it is possible by regular cleaning and use of molluscicides to keep the intensity of diplostomiasis at such a level that rainbow trout do not become severely affected . - pubmed
However , as with other parasitic diseases , a combination of control methods will probably be required to eradicate the disease completely from trout farms . - pubmed
Effects of 2 - deoxy - D - glucose on glycolysis , proliferation kinetics and radiation response of human cancer cells . - pubmed
[ The cytology of some transplanted tumors in the hamster cheek pouch ] . - pubmed
Bovine hyperkeratosis . - pubmed
Experimental relief of spasticity in the cat by lumbosacral radio - frequency cordotomy . - pubmed
[ Changes in the electrocardiogram of rats under normothermia and hypothermia caused by the action of a mediator and catecholamine ] . - pubmed
Polysomes were isolated from an enterotoxigenic strain of Clostridium perfringens during vegetative growth and at 1 - h intervals after transfer into Duncan - Strong sporulation medium . - pubmed
Endoscopic electrocoagulation was considered in 69 patients with active gastroduodenal bleeding including 60 patients with peptid ulcer . - pubmed
Six children in whom an intussusception was diagnosed on a small bowel follow - through examination are presented . - pubmed
This domain , which begins at the amino - terminus and ends at residue 415 , is a major autoantigen in human autoimmune thyroid disease . - pubmed
Tissues were surgically obtained from epileptic patients with hippocampal sclerosis and compared with specimens from patients with seizures originating from temporal lobe tumors and autopsy controls . - pubmed
Enhanced 45Ca2 + efflux in cultured vascular smooth muscle cells from spontaneously hypertensive rats . - pubmed
In the present study we have compared these two Ca2 + effluxes in cultured aortic smooth muscle cells derived from spontaneously hypertensive rats ( SHR ) and Wistar - Kyoto normotensive rats ( WKY ) . - pubmed
To determine the spectrum of systemic diseases associated with pauci - immune necrotizing crescentic glomerulonephritis , we have analysed extra - renal manifestations , occurrence of extra - glomerular vasculitis and incidence and specificity of antinuclear cytoplasmic antibodies ( ANCA ) in 40 patients selected only on renal histological criteria . - pubmed
Among the 33 patients with suspected or established vasculitis , 13 had presumed or biopsy - proven Wegener ' s granulomatosis , three had a macroscopic form of polyarteritis nodosa and 17 could not be adequately classified . - pubmed
Seventy - three hypertensive patients , aged 65 and over , entered the study . - pubmed
The first goal of this clinical study was to define MOF ; the second was to assess the typical onset , sequence , and pattern of MOF ; and the third was to define certain risk factors for the development of MOF in 342 multiple trauma patients . - pubmed
Patients with dermatitis herpetiformis , similar to patients with coeliac disease not adhering to a gluten free diet , seem to have increased risk for lymphoma . - pubmed
AIMS : This study looked at the occurrence of malignancy and survival of patients with dermatitis herpetiformis and compared the results with those seen in patients with coeliac disease or in the general population . - pubmed
PATIENTS : A total of 305 adult patients with dermatitis herpetiformis diagnosed at the University Hospital of Tampere in 1970 - 1992 were studied . - pubmed
A control group comprised 383 adult patients with coeliac disease , 81 % of them adhered to a gluten free diet , 6 % had a normal diet , and in 13 % the diet history remained unknown . - pubmed
METHODS : The occurrence of malignant diseases and survival of the patients were assessed up to the end of 1993 . - pubmed
RESULTS : Thirteen ( 4.3 % ) patients with dermatitis herpetiformis developed 14 malignant disorders during the follow up ( SIR 1.25 ; 95 % confidence intervals 0.68 to 2.09 ) . - pubmed
A non - Hodgkin ' s lymphoma occurred in four patients with dermatitis herpetiformis , significantly more than expected ( SIR 10.3 ; 2.8 - 26.3 ) . - pubmed
Thirteen ( 4.3 % ) patients with dermatitis herpetiformis died during the follow up but there was no increased general mortality . - pubmed
In coeliac disease , 13 ( 3.4 % ) patients developed malignancy ( SIR 1.16 ; 0.62 to 1.97 ) , 31 ( 8.1 % ) patients died but the survival rate did not differ from that in the general population . - pubmed
CONCLUSIONS : The incidence of non - Hodgkin ' s lymphoma was significantly increased in patients with dermatitis herpetiformis . - pubmed
The results also confirm that the patients with dermatitis herpetiformis treated mainly with a gluten free diet have no increased general mortality . - pubmed
However , oestrogen therapy may often not be appropriate because of clinical contraindications , side effects or patient concerns regarding the risk of breast cancer . - pubmed
METHODS : Data for 59,876 cancer - registry patients aged 50 - 79 were analysed . - pubmed
In cases of endophthalmitis all therapeutical options have to be performed as soon as possible to save the patient 's eye and sight . - pubmed
Potent antiretroviral therapy can reduce human immunodeficiency virus ( HIV ) in plasma to levels below the limit of detection for up to 2 years , but the extent to which viral replication is suppressed is unknown . - pubmed
Infection of a susceptible host with the blood fluke Schistosoma mansoni results in the formation of periovular granulomas and subsequent fibrosis in the target organs . - pubmed
Although the prevalence of significant hypoglycaemia following pancreas transplantation remains unknown , it is important to conduct studies to determine the mechanisms , the natural history , predictors and treatment as well as the long - term prognosis ( graft and patient survival rates ) of type 1 diabetic patients who develop pancreas - allograft - associated hypoglycaemia . - pubmed
Finally , whether postpancreas allograft transplantation - associated hypoglycaemia in type 1 diabetic patients carries greater morbidity and mortality when compared to those without hypoglycaemia deserves to be investigated . - pubmed
[ The mineral density of the bone tissue in patients with rheumatic diseases of the joints ( based on x - ray densitometry data ) ] . - pubmed
Manifestations were studied of systemic osteoporosis in patients with rheumatoid arthritis , primary osteoarthrosis , and ankylosing spondylarthritis . - pubmed
A conclusion has been reached that it is necessary that the above - mentioned studies be made in order that we might choose relevant therapeutic alternatives for patients with rheumatic afflictions of the joints . - pubmed
At the end of the observation period signs of left ventricular backward failure were , however , detected in 75 rats with placebo and in 67 rats treated with quinapril ( P=0.229 ) . - pubmed
Clinical trials have shown infliximab to be effective in producing and maintaining a clinical response in patients with refractory , moderate to severe CD . - pubmed
Infliximab appears useful in the treatment of CD and may improve patients ' quality of life . - pubmed
The aim of this study was to compare the effects of different rates of application of a commonly used physiotherapeutic spinal manipulative therapy technique on sympathetic function in normal pain - free volunteers . - pubmed
Patients with end - stage renal disease ( ESRD ) suffer from a secondary form of complex dyslipidemia consisting of both quantitative and qualitative abnormalities in serum lipoproteins resulting from alterations in lipoprotein metabolism and composition . - pubmed
The contribution of this complex and atherogenic form of dyslipidemia to cardiovascular disease in patients with renal disease is unclear at present . - pubmed
Nevertheless , patients with renal disease belong to a very high cardiovascular risk group and dyslipidemia should most likely be subjected to sufficient lipid - lowering therapy in most patients . - pubmed
Seven healthy volunteers with no family history of NIDDM were studied on two occasions during a 12 - h oscillatory glucose infusion with a periodicity of 144 min . - pubmed
METHODS : From 1993 to 2000 , 74 patients with pathological T1N0M0 lung cancer were treated by the pulmonary artery - guided segmentectomy . - pubmed
According to tumor size , the 5 - year survival rate for patients with tumors of 20 mm or smaller ( 92.9 % , n=53 ) was higher than that for the patients with tumors of 21 - 30 mm ( 63.0 % , n=21 ) , but the difference did not reach statistical significance . - pubmed
Locoregional recurrences occurred in one of 53 patients ( 1.9 % ) with tumors 20 mm or smaller and in seven of 21 patients ( 33.3 % ) with tumors 21 - 30 mm , the difference being statistically significant ( P<0.01 ) . - pubmed
CONCLUSIONS : Our intermediate results demonstrated that the new pulmonary artery - guided segmentectomy could be an alternative method for selected patients with small lung cancer , particularly with tumors 20 mm or smaller in diameter . - pubmed
Fifteen months after lamivudine treatment was started , a breakthrough due to lamivudine - resistant strain M5521 occurred . - pubmed
Recent studies define a subgroup of patients at higher risk of renal failure during induction chemotherapy . - pubmed
All children were treated for lymphoproliferative malignancy with conventional preventive measures . - pubmed
RESULTS : Three children needed haemodialysis--2 boys had fully expressed TLS with ARF shortly after starting chemotherapy , in 1 boy the dialysis was indicated because of extreme hyperuricemia and high creatinine level presented before chemotherapy . - pubmed
OBJECTIVES : To compare the degree of osteoporosis and bone metabolism markers between elderly women with COPD and those with bronchial asthma who had never received chronic systemic corticosteroids , and to determine the factors influencing bone metabolism in these patients . - pubmed
PATIENTS : A total of 44 elderly female patients with COPD ( n = 20 ) or bronchial asthma ( n = 24 ) who had not received chronic systemic corticosteroids were enrolled ( mean + /- SEM age , 74.6 + /- 1.0 years ) . - pubmed
Clean MAS observation of 13C - labeled carbons in membrane - bound HIV-1 and influenza fusion peptides was made by using a rotational - echo double - resonance spectroscopy ( REDOR ) filter of directly bonded 13C-15N pairs . - pubmed
Influence of suspended solids on acute toxicity of carbofuran to Daphnia magna : I. Interactive effects . - pubmed
[ Chronic polyarthritis in children treated by delta 5 pregnenolone ] . - pubmed
[ EXPERIENCE WITH DISPENSARY SERVICES TO PATIENTS WHO RECOVERED FROM EPIDEMIC HEPATITIS IN INFECTIOUS DISEASE CLINICS ] . - pubmed
[ The circulatory system in patients with familial hypercholesterolemic xanthomatosis ] . - pubmed
Furthermore , no studies have compared prophylactic therapy for every patient versus therapy only for those patients who experience AF after heart surgery . - pubmed
OBJECTIVES : To report one case of adrenal gland cyst in a patient presenting with lower urinary tract symptoms . - pubmed
OBJECTIVE : To evaluate the effectiveness of tramadol hydrochloride for the treatment of chronic pain refractory to previous treatment in two pediatric patients . - pubmed
METHODS : Tramadol hydrochloride was administered ( 50 mg / day to 150 mg / day ) to two siblings with Ehlers - Danlos syndrome - Hypermobility type refractory to previous pharmacological treatments , and changes in pain intensity and physical activity were assessed . - pubmed
CONCLUSIONS : Tramadol hydrochloride was a safe and effective treatment for relieving chronic pain in two pediatric patients suffering from the hypermobility type of Ehlers - Danlos syndrome . - pubmed
OBJECTIVE : Renal and hormonal abnormalities , manifesting as oedema or hyponatraemia , are often seen in patients with COPD . - pubmed
The aim of this study was to investigate the effect of airflow obstruction and arterial blood gas abnormalities on oedema formation in COPD patients . - pubmed
METHODOLOGY : A total of 58 COPD patients hospitalized for treatment of COPD exacerbation were admitted to the study . - pubmed
Of these , 38 patients had peripheral oedema ( group 1 ) and 20 patients had no oedema ( group 2 ) . - pubmed
Hyponatraemia occurred in five patients ( 13 % ) in group 1 and one patient ( 5 % ) in group 2 . - pubmed
CONCLUSION : Alterations in pH and PaCO2 ( respiratory acidosis and hypercapnia ) appear to have more prominent roles than hypoxaemia in oedema formation in COPD patients . - pubmed
Circadian blood pressure profile in patients with Cushing ' s syndrome before and after treatment . - pubmed
The aim of the study was to evaluate the circadian blood pressure ( BP ) profiles in patients with two forms of Cushing ' s syndrome , and to compare them to those in patients with essential hypertension . - pubmed
The study included 100 patients with Cushing ' s syndrome ( 80 with pituitary adenomas and 20 with adrenal adenomas ) and 40 with essential hypertension . - pubmed
The awake - sleep differences between the patients with two forms of Cushing ' s syndrome were similar . - pubmed
The night - time BP decline in the patients with Cushing ' s disease , as well as in those with adrenal adenomas , was significantly lower than that in the patients with essential hypertension . - pubmed
In the patients with both forms of Cushing ' s syndrome , there was a highly significant decline in the office and ambulatory BP levels after the treatment , and the awake - sleep systolic BP difference became significantly higher . - pubmed
The night - time diastolic BP decline was significantly higher after treatment in patients with adrenal adenomas and not - significantly higher in patients with Cushing ' s disease . - pubmed
In the patients with Cushing ' s disease , the duration of hypertension was greater , and lower percentage of normalized BP after treatment was observed in comparison with the patients with adrenal adenomas . - pubmed
Between December 1998 and July 2002 , we operated on 12 patients with multiple thoracic disc herniations . - pubmed
PATIENTS AND METHODS : This is a retrospective study including 83 patients who underwent emergency operations for completely obstructing colorectal cancers from 1991 to 2002 . - pubmed
The effect of electromagnetic terahertz oscillations at frequencies of the molecular spectrum of nitric oxide radiation and absorption ( 150.176 - 150.664 GHz ) on the properties of blood coagulation in white laboratory rats subjected to immobilization stress was studied . - pubmed
Clinical outcome in patients with bipolar I disorder , obsessive compulsive disorder or both . - pubmed
A cross - sectional survey on a cohort of HIV - infected women seen at 27 HIV clinics was performed . - pubmed
PURPOSE : This review aims to provide a literature survey of the association between photo - oxidation of lens proteins and lipid peroxidation with the genesis of age - related cataract in laboratory studies using rodent models , in epidemiological and interventional studies in humans . - pubmed
Dietary antioxidants are central in retarding cataractogenesis , although most evidence for this is gained from laboratory - based work on relatively unphysiologic rodent cataract models , using antioxidant regimes that could not be sustained in clinical practice . - pubmed
DESIGN : Twenty limbs of 18 patients with venous leg ulcers were studied , median age 76 years . - pubmed
Death at a discount : how the tobacco industry thwarted tobacco control policies in US military commissaries . - pubmed
Repair of oronasal fistulae using auricular cartilage grafts in five cats . - pubmed
OBJECTIVE : To describe repair of chronic palatine defects in cats , with free cartilage graft harvested from either the pinna ( scapha ) or vertical ear canal ( annular cartilage ) . - pubmed
ANIMALS : Cats ( n=5 ) with chronic oronasal fistula . - pubmed
CONCLUSIONS : Auricular cartilage provides a reliable framework for repair of oronasal fistulae in cats . - pubmed
We recommend using conchal cartilage as the initial treatment approach for repair of small oronasal fistulae in cats . - pubmed
Effect of a vigorous aerobic regimen on physical performance in breast cancer patients - a randomized controlled pilot trial . - pubmed
This randomized , controlled pilot trial was carried out to assess the feasibility and efficacy of an aerobic exercise in enhancing physical performance of breast cancer patients after adjuvant treatments . - pubmed
Extrahepatic abdominal hydatid disease caused by Echinococcus granulosus : imaging findings . - pubmed
OBJECTIVE : The classical findings in hydatid disease caused by Echinococcus granulosus with liver or lung involvement are well known . - pubmed
Treating patients with overactive bladder syndrome with antimuscarinics : heart rate considerations . - pubmed
The emergence and spread of the PVYNTN strain , which is the causative agent of potato tuber necrotic ringspot disease ( PTNRD ) , has lead to large economic losses and highlighted the need for accurate discrimination of the different PVY strains . - pubmed
BACKGROUND : Fast changes in human demographics worldwide , coupled with increased mobility , and modified land uses make the threat of emerging infectious diseases increasingly important . - pubmed
METHODOLOGY / PRINCIPAL FINDINGS : We develop an extension of standard epidemiological models , appropriate for emerging infectious diseases , that describes the probabilistic progression of case numbers due to the concurrent effects of ( incipient ) human transmission and multiple introductions from a reservoir . - pubmed
We apply the methodology to case data from World Health Organization reports to place bounds on the current transmissibility of H5N1 influenza in humans and establish a statistical basis for monitoring its evolution in real time . - pubmed
I will suggest that a diverse group of vasculitic disease entities , with similar histologic patterns of vascular inflammation , are the result of this mechanism , inherited from the social amoebae and invertebrate echinoderms at the very base of the deuterostome lineage . - pubmed
STA-9090 activity was tested in a canine mastocytoma xenograft model . - pubmed
Lastly , STA-9090 inhibited tumor growth in a canine mastocytoma mouse xenograft model . - pubmed
METHOD : We searched for articles in English published in peer - reviewed journals that perform cost - utility analyses to evaluate the addition of HPV vaccine to 12 - year - old girls to existing cervical cancer screening practices . - pubmed
In this case report , we describe a 7 - year - old patient with isolated lung epithelial - myoepithelial carcinoma and the management of such a lesion . - pubmed
SUMMARY : Infection of the snail , Biomphalaria glabrata , by the free - swimming miracidial stage of the human blood fluke , Schistosoma mansoni , and its subsequent development to the parasitic sporocyst stage is critical to establishment of viable infections and continued human transmission . - pubmed
OBJECTIVES : To isolate and characterize human muscle - derived cells ( MDCs ) for future management applications on lower urinary tract symptoms , including stress urinary incontinence and bladder reconstitution . - pubmed
The development of muscle stem cells for transplantation or gene transfer in patients with muscle disorders has become more attractive and challenging recently . - pubmed
Human MDCs might have the potential to be a novel tool for the management of stress urinary incontinence and bladder reconstitution . - pubmed
Earlier diagnosis , treatment of exacerbations , and the use of long - term therapies have all improved the lifespan of patients with cystic fibrosis ( CF ) . - pubmed
Results showed that the two fermentatively different strains of facultative anaerobes , Escherichia coli E 17 and Klebsiella mobilis ATCC 13048 grew in balance regardless of oxygen level , bile acid concentration or other components of the mixed cultures , Bacillus cereus or Staphylococcus aureus . - pubmed
Only 13.24 % of the 287 patient samples were sterile , and around 180 strains of both E. - pubmed
Enterococcus sp . accounted for 246 isolates being the largest group of strains ( 24.25 % of all the isolates ) . - pubmed
48 % of patients had a prior myocardial infarction and 25 % had already coronary bypass surgery ( CABG ) . - pubmed
PATIENTS AND METHODS : Four seborrheic blepharitis patients with Malassezia spp . - pubmed
Different aspects of the Lewis ( x ) glycomimetic peptide were investigated by introducing it in in vitro assays measuring neurite outgrowth and in in vivo assays to determine its efficacy in regeneration of peripheral nerve and spinal cord after injury in adult mice . - pubmed
For lymphadenectomy to have clinical utility in the care of women with stage IA2 cervical carcinoma , a sufficiently high incidence of node positivity would be required to justify the morbidity of the procedure for the whole group . - pubmed
We assessed structural changes on brain imaging and neuropsychological outcomes in critically ill patients who developed neurological changes during their intensive care unit ( ICU ) stay . - pubmed
Patients with idiopathic PAH ( IPAH ) ( n = 44 ) and normal individuals ( n = 13 ) served as control subjects . - pubmed
Chronic treatment with D - chiro - inositol prevents autonomic and somatic neuropathy in STZ - induced diabetic mice . - pubmed
METHODS : Streptozotocin - induced ( STZ ) diabetic mice were treated by oral gavage for 60 days with DCI ( 20 mg / kg/12 h ) or saline ( NaCl 0.9 % ; 0.1 ml/10 g/12 h ; Diab ) and compared with euglycaemic groups treated with saline ( 0.1 ml/10 g/12 h ; Eugly ) . - pubmed
It is based on the ex vivo expansion and activation of tumor - specific T lymphocytes extracted from the tumor and their administration back to the patient . - pubmed
BACKGROUND : Statins are an important part of the treatment plan for patients with type 2 diabetes . - pubmed
OBJECTIVE : To estimate the influence of adherence on the optimal timing of statin initiation for patients with type 2 diabetes . - pubmed
It has increasing importance for liver transplant ( OLT ) patients , in particular if when there is decreased renal function . - pubmed
In 10 patients , the cholestasis associated with chronic rejection was sharply reduced after the introduction of sirolimus . - pubmed
CONCLUSION : Sirolimus given alone or in combination with CNIs appears to be an effective primary immunosuppressant regimen for OLT patients . - pubmed
RESULTS : Green tea intake ( & gt;=500 ml / d ) was inversely associated with ccRCC risk , with an AOR of 0.34 ( 95 % CI 0.21 - 0.55 ) . - pubmed
CONCLUSION : BMI ( & gt;=25 kg / m(2 ) ) , hypertension , and urolithiasis are independently associated with an increased risk , whereas green tea intake ( & gt;=500 ml / d ) is independently associated with a decreased risk of ccRCC . - pubmed
With the increasing rate of obesity and the potentially simultaneous development of sarcopenia , bedrest presents a difficult clinical challenge to the elderly individual . - pubmed
Development of a home - based telehealthcare model for improving the effectiveness of the chronic care of stroke patients . - pubmed
This study describes the development of an information technology ( IT)-mediated home - based healthcare model designed to improve the effectiveness of caring for stroke patients who require chronic , home care . - pubmed
This model was evaluated at Kaohsiung Medical Hospital in Taiwan between 2005 and 2008 ; 84 newly diagnosed stroke patients diagnosed as the chronic covalence stage were enrolled for preliminary testing of this model . - pubmed
Evaluation of the trachea and intrathoracic airways by the acoustic reflection method in children with cystic fibrosis . - pubmed
Tracheomalacia has been observed in older patients with cystic fibrosis ( CF ) . - pubmed
The mean MTAv value was comparable in the CF patients and the control subjects during SB , FI , and FE . - pubmed
A 62 - year - old man with a right subclavian artery aneurysm had had a history of bird hunting using a shotgun that impacted substantially against his right clavicula and shoulder weekly for & gt;20 years . - pubmed
The availability of suitable animal models and the opportunity to record electrophysiologic data in movement disorder patients undergoing neurosurgical procedures has allowed researchers to investigate parkinsonism - related changes in neuronal firing patterns in the basal ganglia and associated areas of the thalamus and cortex . - pubmed
Type 2 diabetes mellitus in mice aggravates the renal impact of hemorrhagic shock . - pubmed
The objectives of this study were to determine whether type 2 diabetic mice would exhibit a more severe renal impact of hemorrhagic shock ( HS ) based on a recently described model of acute kidney injury and to determine the impact of HS on renal responses to hypoxia . - pubmed
We induced HS or sham procedure in type 2 diabetic and obese db / db mice . - pubmed
Diabetic mice exhibiting mild diabetic nephropathy express hypoxic signals at baseline . - pubmed
The renal impact of HS was more severe in diabetic mice , with a worsening of tissular hypoxia and an altered response to hypoxia . - pubmed
Renal impact of HS in type 2 diabetic mice is more intense than in nondiabetic ones . - pubmed
METHODS AND RESULTS : A total of 5953 Danish men and women aged 30 - 60 years without baseline diabetes or cardiovascular diseases were included in this prospective analysis . - pubmed
Non - Hodgkin ' s lymphoma in a patient on treatment with temozolomide . - pubmed
A 68 - year - old man was diagnosed with glioblastoma multiforme of the right basal ganglia in March 2010 . - pubmed
In the present review , we discuss the phenotypic differences between mice of the inbred C57BL/6J and DBA/2J strains that could be associated with the strain - specific resistance to helplessness observable in DBA/2J mice . - pubmed
Variables significantly associated with increased cost in the multivariate analysis were complicated pneumonia ( & gt;=2 and 1 complication ) versus non - complicated pneumonia ( $ 4919 and $ 2822 vs. $ 1399 ) , performance of surgery versus no surgery ( $ 4849 vs. $ 1435 ) , intensive care versus no intensive care ( $ 6488 vs. $ 3862 ) and identification of non - PCV7 serotypes versus PCV7 serotypes ( $ 4656 vs. $ 1470 ) . - pubmed
CONCLUSION : Invasive pneumococcal pneumonia in children makes substantial demands on hospital health care and financial resources that could be mitigated with universal PCV13 childhood immunization programmes and early management of complications . - pubmed
One hundred and fifty - six women age 18 - 65 years were enrolled at diagnosis of first venous thromboembolism ( VTE ) . - pubmed
The application and efficacy of combined neurofeedback therapy and imagery training in adolescents with Tourette syndrome . - pubmed
We aimed to examine the effectiveness of combined neurofeedback therapy and imagery training in adolescent patients with refractory Tourette syndrome . - pubmed
Patients showed significant improvement in motor tic and vocal tic symptoms , exemplified by a reduction in the frequency and intensity of tics , indicating that neurofeedback , together with imagery training , has a positive therapeutic effect on adolescent patients with medication - refractory Tourette syndrome . - pubmed
The overexpression of peptide receptors in many human cancers has attracted an enormous interest in targeting molecules for the development of tumor - specific radiopharmaceutical compounds for diagnostic imaging and therapy of cancers . - pubmed
Selective detection of tumor cells while sparing normal tissue is possible and peptide - receptor ligands are the tools for obtaining the probes needed to explore specific biological and pathological processes in both animals and humans . - pubmed
METHODS AND RESULTS : Consecutive patients having undergone PVs isolation as repeat procedure for recurrent AF after an initial CB ablation were eligible for this study . - pubmed
At mean 20.2 + - 10.7 months follow - up , a total of 16 patients ( 55 % ) were free of AF at without antiarrhythmic drugs ( AADs ) . - pubmed
Adenoviral vectors carrying the enhanced green fluorescent protein ( EGFP ) transgene were used at different multiplicities of infection ( MOI ) to infect multiple cell types , both in standard static and in perfused conditions . - pubmed
Our results validate the mathematical models and demonstrate how the infection processes through perfusion via microfluidic platform led to an enhancement of adenoviral infection efficiency even at low MOIs . - pubmed
OBJECTIVE : To explore the evidence regarding the effectiveness of dry needling to reduce pain in patients with MPS of the upper quarter . - pubmed
The findings of 3 studies that compared dry needling to sham or placebo treatment provided evidence that dry needling can immediately decrease pain in patients with upper - quarter MPS , with an overall effect favoring dry needling . - pubmed
The findings of 2 studies that compared dry needling to sham or placebo treatment provided evidence that dry needling can decrease pain after 4 weeks in patients with upper - quarter MPS , although a wide confidence interval for the overall effect limits the impact of the effect . - pubmed
CONCLUSION : Based on the best current available evidence ( grade A ) , we recommend dry needling , compared to sham or placebo , for decreasing pain immediately after treatment and at 4 weeks in patients with upper - quarter MPS . - pubmed
A 40 - year - old man with a medical history of hypertension was admitted for weight loss , generalised weakness , joint pains and mottling of fingertips . - pubmed
METHODS : From August 2011 to November 2011 , 25 patients with ACL injuries were treated with arthroscopic reconstruction of ACL using hamstring tendon . - pubmed
Fifteen patients had injuries in left knees , and 10 patients had injuries in right knees . - pubmed
The duration of the disease ranged from 1 to 60 d , with a mean of 9.6 d. All patients with acute injuries had swelling and pain on the knee , and anterior drawer test showed positive results in 14 cases , Lachman test showed positive results in 17 cases . - pubmed
Among patients with old injuries , 5 patients had knee joint pain , 5 patients had unstability of knee joint , 5 patients had positive results of anterior drawer test , and 5 patients had positive results of Lachman test . - pubmed
There were 20 patients with acute injuries and 5 patients with old injuries . - pubmed
RECENT FINDINGS : Symptoms in men with chronic prostatitis / CPPS appear to cluster into a group with primarily pelvic or localized disease , and a group with more systemic symptoms . - pubmed
Future therapy may include antibodies to mediators of neurogenic inflammation and even treatment of bacteria in the bowel . - pubmed
SUMMARY : The diagnosis of chronic prostatitis / CPPS must include conditions traditionally outside the scope of urologic practice but important for the care of men with chronic pelvic pain . - pubmed
We present two patients , one of them with suspected biochemical prostate cancer and one with biochemical recurrence after radical treatment . - pubmed
Despite intensive treatment with chemotherapy , radiotherapy and surgery , over 70 % of patients with metastatic Ewing ' s Sarcoma Family of Tumors ( EFT ) will die of their disease . - pubmed
METHODS : To examine prehospitalization symptom scenarios , semistructured interviews were conducted with 60 patients hospitalized for acute decompensated HF . - pubmed
Screening for cognitive and affective dysfunction in patients suspected of mild cognitive impairment . - pubmed
The goal of this study was to determine if patients with mild cognitive impairment ( MCI ) of the amnestic type would demonstrate impairments in these domains , as well as show expected memory deficits . - pubmed
METHODS : Thirty - nine French - speaking patients with a clinical diagnosis of MCI were compared with 39 age- and education - matched normal functioning individuals on the French translation of the Barrow Neurological Institute Screen for Higher Cerebral Functions ( BNIS ) . - pubmed
RESULTS : Patients with MCI performed significantly worse than controls on the BNIS subtests sampling memory , orientation , affect expression and perception , and accurate prediction of memory performance . - pubmed
CONCLUSION : This sample of MCI patients demonstrated disturbances not only in memory but also in self - awareness and affect expression and perception on the BNIS . - pubmed
Successful Electroconvulsive Therapy in a Clozapine - Refractory Schizophrenia Patient with Meningioma . - pubmed
Thus synergistic effects on cypermethrin toxicity of A. - pubmed
Forty - nine people with moderate to severe chronic obstructive pulmonary disease completed 4 months of training and provided valid accelerometry data , and 34 also provided accelerometry data at 12 months of follow - up . - pubmed
METHODS : A subject with Bietti crystalline tapetoretinal dystrophy was evaluated with ophthalmoscopy , fluorescein angiography , and OCT ( Stratus ) . - pubmed
Tumor samples and clinical data were obtained from 50 patients with craniopharyngioma who were admitted to the West China Hospital of Sichuan University ( Chengdu , China ) . - pubmed
Measurement of the endotracheal cuff pressure was continued until the extubation of endotracheal or tracheostomy tube , or death of the patient . - pubmed
The possible influencing factors were evaluated in the two groups , including body mass index ( BMI ) , size of endotracheal tube , duration of intubation , use of sedative or analgesic , number of leaving from intensive care unit ( ICU ) , the number of turning over the patients , and aspiration of sputum . - pubmed
CONCLUSIONS : Abnormal endotracheal cuff pressure is common in critically ill patients with intratracheal intubation . - pubmed
A 7 - year - old boy presented with fever and ataxia 20 days after oral polio vaccination . - pubmed
PATIENTS AND METHODS : Forty - four patients ( 34 male and mean age of 54.9 + - 10.9 years ) with acute STEMI were included . - pubmed
CONCLUSIONS : TPE measured from surface ECG recordings is significantly reduced in STEMI patients with successful reperfusion after primary PCI , as determined by IC - ECG recordings . - pubmed
We present the age - related schedules for immunizations against yellow and typhoid fevers , hepatitis A and B , tick - borne and Japanese encephalitis , and rabies . - pubmed
In experiments , isolate ZJ01 caused death in 100 % of pigs that were either 14 or 80 days old . - pubmed
The impact of oral anticoagulation on time to surgery in patients hospitalized with hip fracture . - pubmed
A significant number of hip fracture patients have concomitant cardiovascular disease requiring anticoagulation . - pubmed
MATERIALS AND METHODS : This is a case control study comparing TTS in consecutively admitted hip fracture patients receiving either a DOAC or VKA with age- and gender - matched controls between January 1 , 2010 and March 24 , 2014 . - pubmed
CONCLUSIONS : Patients on anticoagulation prior to admission for hip fracture experienced longer delays in surgery when compared to patients not receiving anticoagulation . - pubmed
Patients were without significant renal or hepatic failure or shock at entry . - pubmed
Here , we investigated whether systemic perfusion pressure , a key driver of tumor blood flow , could influence the intratumoral extravasation of systemically administered oncolytic vesicular stomatitis virus ( VSV ) in myeloma tumor - bearing mice . - pubmed
OBJECTIVES : The effect of agmatine on bladder contractility and the diabetes - induced alteration of this action were studied in the rat . - pubmed
METHODS : Bladder strips were isolated from 9 - week - old streptozotocin ( STZ)-diabetic rats and control Wistar rats . - pubmed
Relaxation was significantly increased in STZ - diabetic rats . - pubmed
Two of 181 ( 1.1 % ) patients died , 5 of 181 ( 2.8 % ) lost their grafts , 12 of 181 ( 6.6 % ) had an episode of acute rejection , 13 of 181 ( 7.2 % ) had & gt;=1 serious event and infection , and 85 of 181 ( 49.9 % ) had & gt;=1 nonserious adverse event or infection . - pubmed
Suspected laryngeal granuloma secondary to chronic endotracheal intubation in a dog . - pubmed
Prevalence characteristics of high - risk human papillomaviruses in women living in Shanghai with cervical precancerous lesions and cancer . - pubmed
A complete understanding of the natural history of infection with high - risk human papillomaviruses ( HPVs ) in cervical cancer requires data from regional and ethnic studies . - pubmed
The prevalence of high - risk HPVs was evaluated retrospectively in 2040 patients with cervicitis , 239 with cervical intraepithelial neoplasia grade 1 ( CIN1 ) , 242 with CIN2/3 , and 42 patients with invasive squamous cell carcinoma ( SCC ) based on data from patients who visited our hospital between May 2013 and May 2015 . - pubmed
HPV16 and HPV58 positivity in cervicitis , CIN1 , CIN2/3 , and SCC patients were 20.9 % and 16.4 % , 19.0 % and 20.1 % , 44.1 % and 23.5 % , and 60.0 % and 31.4 % , respectively . - pubmed
Compared to cervicitis , the odds ratios ( ORs ) for CIN2/3 in HPV16- and HPV58 - positive patients were 2.99 ( 95 % confidence interval [ CI ] : 1.32 - 4.33 ) and 1.56 ( 1.11 - 3.21 ) , respectively ; for SCC , the corresponding values were 5.68 ( 2.31 - 7.893 ) and 2.33 ( 1.41 - 3.87 ) . - pubmed
Further identifying of carcinogenic HPVs and a fully aware of regional differences in HPV genotype distribution are tasks of top priority for cervical cancer control and prevention . - pubmed
The present study was carried out to investigate the effect and mechanisms of aloe - emodin ( AE)-mediated photodynamic therapy ( AE - PDT ) on the human osteosarcoma cell line MG-63 . - pubmed
After treatment with AE - PDT , the human osteosarcoma cell line MG-63 was tested for levels of viability , autophagy , reactive oxygen species ( ROS ) and apoptosis and changes in cell morphology with the Cell Counting Kit-8 ( CCK-8 ) , monodansylcadaverine ( MDC ) and Hoechst staining and transmission electron microscopy . - pubmed
METHODS : A total of 55 adults with comitant horizontal strabismus participated in a prospective observational clinical series . - pubmed
Thirty - one patients with esodeviations received BPX injections in a lateral rectus muscle , some with BTXA in the medial rectus ; 24 patients with exodeviations received BPX in a medial rectus muscle , some with BTXA in the lateral rectus muscle . - pubmed
[ Contact lens - associated Paecilomyces lilacinus keratitis ] . - pubmed
We present the case of a 23 - year - old otherwise healthy female patient with contact lens - associated Paecilomyces lilacinus keratitis . - pubmed
METHODS : BCP mouse model was established by osteosarcoma cell inoculation . - pubmed
A total of 35 cows were diagnosed and treated for periparturient paresis and , therefore , excluded from the study . - pubmed
In this study , we report a woman with a history of recurrent pregnancy losses ( RPL ) and infertility who had low levels of memory B cells . - pubmed
The subjects were children and adolescents with hypothyroidism due to dyshormonogenetic goiter . - pubmed
Patients with Parkinson ' s disease ( PD ) have higher - order sensory dysfunctions including prolonged temporal discrimination threshold ( TDT ) . - pubmed
METHODS : This study includes 33 PD patients and 24 healthy controls . - pubmed
RESULTS : Compared to healthy controls , TDT was prolonged in the PD patients . - pubmed
Therefore , with the current public health concern on antibiotic resistance globally , in this review , we underscore the need to screen probiotic strains that are used in both livestock and human applications to assure their safety and mitigate their potential in significantly contributing to the spread of antibiotic resistance genes in our natural environments . - pubmed
Methods : Between January 2000 and December 2014 , 60 patients were treated with endovascular aortic stent graft for injury of the aortic isthmus . - pubmed
One patient had a type 1 endoleak without any reintervention . - pubmed
Nonetheless , FAP deficient mice showed similar pathologic kinetics to wildtype controls , and were capable of supporting normal anti - influenza T and B cell responses . - pubmed
OBJECTIVES : The primary objective of this prospective study was to determine the prevalence of paroxysmal atrial fibrillation ( PAF ) in patients aged 40 and above in a population who underwent continuous 24 - hour electrocardiographic monitoring . - pubmed
At least one episode of PAF was detected in 123 patients , a prevalence of 2.5 % ( 95 % CI : 2.1 - 3.0 ) . - pubmed
Transarterial chemoembolization combined with recombinant human adenovirus type 5 H101 prolongs overall survival of patients with intermediate to advanced hepatocellular carcinoma : a prognostic nomogram study . - pubmed
BACKGROUND : Patients with intermediate to advanced hepatocellular carcinoma ( HCC ) are most commonly treated with transarterial chemoembolization ( TACE ) . - pubmed
In the present study , we aimed to determine the survival benefit of TACE with or without H101 for patients with intermediate to advanced HCC and to develop an effective nomogram for predicting individual survival outcomes of these patients . - pubmed
METHODS : We retrospectively collected data from 590 patients with intermediate to advanced HCC who were treated at Sun Yat - sen University Cancer Center between January 2007 and July 2015 . - pubmed
CONCLUSIONS : TACE plus H101 extends the survival of patients with intermediate to advanced HCC . - pubmed
Our proposed nomogram provides individual survival prediction and stratification for patients with intermediate to advanced HCC who receive TACE with or without H101 . - pubmed
The poor predictive quality of currently used animal models in preclinical research is an important cause of the high attrition of promising drug candidates for human autoimmune disease in clinical trials . - pubmed
Examples from own work in a primate multiple sclerosis ( MS ) model illustrate that important lessons can be learned from a critical reassessment of failed drugs in the animal model , which can help improve the animal model and better understand the targeted disease . - pubmed
BACKGROUND : Little is known about physical activity in daily life among patients with sarcoidosis . - pubmed
METHODS : In patients with sarcoidosis , we measured physical activity ( steps per day ) by accelerometry ( SenseWear Armband ) for 1 week . - pubmed
RESULTS : We investigated 57 patients with sarcoidosis ( mean age 50 years , 56 % male , mean DLCO 73 % predicted , mean FVC 91 % predicted , mean 6MWD 525 m , mean steps per day 7,490 ) , of whom n = 14 ( 25 % ) had severe fatigue . - pubmed
MATERIALS AND METHODS : From January 1993 to March 2017 , 130 patients with primary tumors in the APG region who underwent surgical treatment were enrolled . - pubmed
RESULTS : Among the 130 patients , 53.8 % of lesions were benign ( n = 70 ) , 23.8 % were malignant ( n = 31 ) , 14.6 % were vascular malformations ( n = 19 ) , 6.15 % were sialadenitis ( n = 8) , and 1.65 % were cysts ( n = 2 ) . - pubmed
OBJECTIVE : To assess the clinical effectiveness of a wearable patient sensor to improve care delivery and patient outcomes by increasing the total time with turning compliance and preventing pressure injuries in acutely ill patients . - pubmed
Additional clinical trials leveraging technologies like wearable sensors are needed to establish the appropriate frequency and dosing of individualized turning protocols to prevent pressure injuries in at - risk hospitalized patients . - pubmed
The proportion of synchronous metastases was highest for women with lymph node ( 35 % ) , postmastectomy chest wall ( 30 % ) , and in - breast ( 15 % ) recurrence ; 54 % received systemic staging imaging within 30 days of a locoregional recurrence . - pubmed
Conclusion These findings support current recommendations for systemic imaging in the setting of locoregional recurrence , particularly for patients with lymph node or chest wall recurrences . - pubmed
Because most patients with isolated locoregional recurrence will be recommended locoregional treatment , early identification of distant metastases through routine systemic imaging may spare them treatments unlikely to extend their survival . - pubmed
This paper first investigated the anti - inflammation effect of C. - pubmed
Moreover , we first evaluated the anti - RA effects of CRME using collagen - induced arthritis ( CIA ) in DBA/1J mice , and the incidence , clinical score , and joint histopathology were evaluated . - pubmed
The results showed that , compared with the model group , CRME significantly improved symptoms of the arthritis index , limb swelling , and histological findings by decreasing synovial membrane damage , the extent of inflammatory cell infiltration , and the expansion of capillaries in CIA mice . - pubmed
Randomized controlled studies that assessed the effects of dual - task training in stroke patients were included for the review ( last search in December 2017 ) . - pubmed
Two weeks after the onset of FS , leukemic cells appeared on a peripheral blood smear , and the patient was diagnosed with precursor B - cell ALL presenting as nephromegaly and FS . - pubmed
Healthcare use , costs and quality of life in patients with end - stage kidney disease receiving conservative management : results from a multi - centre observational study ( PACKS ) . - pubmed
Proteomic and miRNA analyses , combined with robust bioinformatics , identified circulating biomarkers applicable to diagnose GD , predict GO disease status and optimize patient management . - pubmed
SUMMARY : Noninvasive imaging allows a comprehensive assessment of patients with suspected pulmonary hypertension . - pubmed
Antitubercular treatment for 6 months was completed in all the patients with active peritoneal disease . - pubmed
However , controversy remains as to whether fish oil - enriched enteral nutrition can improve clinical outcomes in adult critically ill patients in intensive care units ( ICUs ) . - pubmed
The aim of this study was to provide an up - to - date systematic review and meta - analysis of all randomized controlled trials of fish oil - containing enteral nutrition addressing relevant clinical outcomes in critically ill patients . - pubmed
Furthermore , subgroup analysis revealed a significant reduction in 28 - d mortality , ICU LOS , and ventilation duration in patients with acute respiratory distress syndrome but not in other subgroups . - pubmed
Further research should focus on the relation between the individual critically ill patients ' immune response , the administration of fish oil , and clinical outcomes . - pubmed
These findings suggested that neural network abnormalities between the thalamus and the frontal lobe can be related to social dysfunction in patients with schizophrenia . - pubmed
Methods : The rat model of depression was established by chronic unpredictable mild stress ( CUMS ) method for 6 weeks . - pubmed
The sucrose preference test and the forced swimming test were performed to assess the rats ' depression behavior . - pubmed
Conclusions : Energy deficiency and damaged mitochondrial ultrastructure were found in hippocampus and gastrocnemius muscle of depressed rats established by CUMS . - pubmed
Disrupted Plasma Membrane Protein Homeostasis in a Xenopus Laevis Model of Retinitis Pigmentosa . - pubmed
Patients with a unilaterally swollen optic nerve and normal visual function most likely have optic nerve head drusen . - pubmed
Patients with abnormal visual function most likely have demyelinating optic neuritis or non - arteritic anterior ischaemic optic neuropathy . - pubmed
Patients with bilaterally swollen optic nerve heads and normal visual function most likely have papilloedema , and require neuroimaging followed by lumbar puncture . - pubmed
The cumulative proportion of relapse - free patients in time was analyzed by Kaplan - Meier curves . - pubmed
Thermal ablation versus cryotherapy or loop excision to treat women positive for cervical precancer on visual inspection with acetic acid test : pilot phase of a randomised controlled trial . - pubmed
BACKGROUND : Cryotherapy is standard practice for treating patients with cervical precancer in see - and - treat programmes in low - income and middle - income countries ( LMICs ) . - pubmed
Coxiella burnetii , the etiologic agent of Q fever , replicates in an intracellular phagolysosome with pH between 4 and 5 . - pubmed
It has been reported that platelet aggregability is enhanced in patients with OSAS . - pubmed
The objective of this study was to evaluate a contemporary series of patients with STEMI and OHCA to characterize treatment approaches and predictors of neurologic outcome . - pubmed
At hospital presentation , 76 % of patients were intubated , 37 % were in cardiogenic shock , and 33 % were receiving vasopressors . - pubmed
A single immunotherapy agent , Pembrolizumab , is the only currently approved treatment option in subset of patients with unresectable locally advanced , recurrent , or metastatic esophageal , gastroesophageal , or gastric cancers after failure or intolerance of initial systemic treatments . - pubmed
Obesity is one of the main causes of human cardiovascular and cerebrovascular diseases . - pubmed
Baicalin , a bioactive flavonoid isolated from the herbal medicine Scutellaria baicalensis Georgi , is reported to ameliorate obesity and hyperlipidemia . - pubmed
Factors Associated with Poor Outcomes in Patients with Mild or Moderate Acute Subdural Hematomas . - pubmed
The 66 moderate ASDH patients exhibited significantly higher frequencies of surgery and mortality ( 24.2 % and 13.6 % , respectively ) than the 200 mild ASDH patients ( 8.0 % and 4.5 % , respectively ) . - pubmed
The factors associated with poor outcomes were age ( odds ratio [ OR ] : 1.06 ) and the ISS ( OR : 1.24 ) in the mild ASDH patients , and older age ( OR : 1.09 ) and the higher ISS ( OR : 1.15 ) in the moderate group , too . - pubmed
Since the elimination of dog and terrestrial wild animal rabies , bat exposures remain the only source of autochthonous lyssavirus transmission to humans in Western Europe . - pubmed
European bats have already been found infected with several lyssaviruses , and human - bat interactions represent a risk of viral transmission and fatal encephalitis for humans . - pubmed
Effect of diallyl disulfide and garlic oil on different human astrocytoma cell lines . - pubmed
Despite significant efforts to optimize treatment options for patients with high - grade glioma , the prognosis of the overwhelming majority of patients remain poor . - pubmed
The aim of the present study was to investigate the potential anti - glioma properties of DAD and garlic oil on proliferation and induction of apoptosis in four different types of glioma cell lines representative of different grades of the disease . - pubmed
The results showed that garlic oil exhibits favorable anti - cancer potential towards gliomas of various degrees of differentiation . - pubmed
This report describes the cases of two patients with a maxillary lateral incisor with palatogingival groove and extensive endodontic - periodontal lesions . - pubmed
Case Presentation : We report a case of 66 - year - old man with forgotten ureteral stent for 10 years , which caused panureteral damage . - pubmed
At embryonic day ( E ) 18 ( term ~E22 ) , placental insufficiency was induced in pregnant Wistar rats via bilateral uterine vessel ligation to generate IUGR offspring ( n = 10 ) ; control offspring ( n = 11 ) were generated via sham surgery . - pubmed
In IUGR versus control rats there was no difference in object preference in the NOL or NOR , the similar and dissimilar condition of the SLR task , or in locomotion and anxiety - like behavior in the open field . - pubmed
Enzyme studies in human breast tumours . - pubmed
To test the efficacy and toxicity of colloidal bismuth subcitrate ( CBS ) in a double - blind trial , forty - six consecutive outpatients with active duodenal ulceration were randomly allocated either to treatment with CBS or to a placebo for a period of four weeks . - pubmed
The symptomatic assessment of the patients receiving CBS or placebo showed that the reduction in pain was highly significant in both groups , but there was statistically significant difference in the degree of reduction of duodenal ulcer size in favour of the colloidal bismuth subcitrate - treated group ( p less than 0.025 ) . - pubmed
CALLA reacts with leukemic cells of 110 of 134 patients ( 82 % ) with non - T - cell ALL ; 1 of 71 ( 1 % ) patients with acute myelogenous leukemia ( AML ) ; 2 of 7 patients ( 29 % ) with chronic myelogenous leukemia in blast crisis ; 7 of 92 patients ( 8 % ) with other hematologic malignancies ; and with the leukemic cell lines Laz 221 and NALM-1 . - pubmed
It does not react with the normal hematopoietic cells , B - or T - cell lines , or cells from 26 patients with T - cell ALL that were tested . - pubmed
A study of 46 patients has shown that Clonazepam is an effective drug in preventing attacks of pain in essential trigeminal and glossopharyngeal neuralgia and in Sluder ' s syndrome . - pubmed
A patient is described in whom electrocardiographic changes simulating acute nontransmural myocardial infarction occurred in association with head trauma . - pubmed
Polymorphonuclear leukocytes from burned patients exhibit suppressed chemotaxis possibly related to the susceptibility of such patients to opportunistic infection . - pubmed
The chemotactic impairment found in leukocytes from burned patients , however , while related to burn size and predictive of prognosis , did not vary with the agent used for the topical therapy . - pubmed
Twenty patients with symptomatic vascular rings were evaluated preoperatively with echocardiography at this institution . - pubmed
Most ( 17/20 ) presented with respiratory symptoms in the first year of life , although in 3 patients dysphagia was the primary complaint ( at birth , 4 months , 9 years ) . - pubmed
Barium esophagogram remains the best screening test for children in whom a vascular ring is suspected . - pubmed
[ Kinetics of vaccination antibodies against tetanus toxoid , diphtheria toxoid , measles virus , poliomyelitis virus and pneumococcus after allogenic and autologous bone marrow transplantation and booster vaccination . - pubmed
In the second part of the paper we report on the results of the diphtheria antitoxin valuation of 8 children after allogeneic bone marrow transplantation ( BMT ) with and without graft versus host disease ( GvHD ) as well as on the kinetics of the diphtheria antitoxin of 5 children after allogeneic BMT with and without GvHD and of 5 children after autologous transplantation . - pubmed
A genetic animal model of anxiety . - pubmed
Nervous pointer dogs have been suggested as an animal model for pathological anxiety . - pubmed
BACKGROUND : Clinical and morphological studies clearly indicate that most human coronary artery stenoses are capable of vasomotion . - pubmed
Borrelia burgdorferi : another cause of foodborne illness ? - pubmed
Borrelia burgdorferi was identified as the etiological agent of Lyme disease in 1982 . - pubmed
In humans , the symptoms of Lyme disease , which manifest themselves days to years after the onset of infection , may involve the skin , cardiac , nervous and/or muscular systems , and so misdiagnosis can occur . - pubmed
Multiple learning tasks in patients with ideomotor apraxia . - pubmed
The Authors studied a group of patients with ideomotor apraxia ( LBD+ ) to verify if these patients had some difficulties in multiple learning tasks in respect to non - apraxic patients and normal control subjects . - pubmed
On the other hand , this could be tied to an aspecific more diffuse deterioration of attention if we consider that our apraxic patients had a greater cerebral lesion than non - apraxic patients . - pubmed
Inhibitory effects of beta - carotene on preneoplastic lesions induced in Wistar rats by the resistant hepatocyte model . - pubmed
The inhibitory effects of beta - carotene ( BC ) on preneoplastic lesions induced in male Wistar rats by the resistant hepatocyte model was investigated . - pubmed
Preliminary characterization of a persistent infection of HeLa cells with human rhinovirus type 2 . - pubmed
A 50 - year - old woman had seronegative polyarthritis for three years , followed by vascular obstruction with classic Takayasu ' s arteritis . - pubmed
Although persistent infection with hepatitis B virus and woodchuck hepatitis virus has been associated with development of hepatocellular carcinoma in the host , little has been known of such an association with ground squirrel hepatitis virus ( GSHV ) , which is closely related to the woodchuck virus . - pubmed
Colonies of GSHV - infected and -uninfected Beechey ground squirrels were observed for tumors for a period of 5 years . - pubmed
Integrated GSHV DNA was found in the hepatocellular carcinoma tissue of the one carrier animal examined , paralleling the frequent findings of integrated hepatitis B and woodchuck hepatitis viral DNA in human and woodchuck hepatocellular carcinoma . - pubmed
Although the incidence of liver carcinoma reported here in carrier ground squirrels is neither as great as that in carrier woodchucks nor statistically different from the incidence in noncarrier squirrels , the data presented suggest that persistent infection with GSHV may also be associated with hepatocellular carcinoma . - pubmed
Bronchial hyperreactivity was studied in 79 patients who gave a history of allergic symptoms . - pubmed
The influence exerted by the specific immunotherapy ( SIT ) of delayed hypersensitivity ( DH ) to staphylococci and subsequent sensitization with tarragon pollen on the level of immunocompetent cells in the blood and lymphoid organs of guinea pigs was studied . - pubmed
DNA 's from human hepatoma and gastric cancer mitochondria . - pubmed
[ Simian malaria in the State of Acre , Brazil : the finding of titi monkeys , Callicebus moloch cupreus , infected with Plasmodium brazilianum ] . - pubmed
The influencing of post - traumatic haemorrhage by ellagic acid in rats whole - body irradiated with 600 R. - pubmed
Major coronary thrombi formation in the unanesthetized animal . - pubmed
[ Bone iopsy in cattle - possibilities of chemical and histological examination to diagnose cases of osteopathy due to mineral deficit ] . - pubmed
In a double - blind , crossover study gamma - vinyl GABA , 2 g / day , and placebo were administered orally for 2 weeks each to six patients with Huntington ' s disease . - pubmed
Ultrasonic examination of the parathyroid glands has been used in 50 consecutive patients with surgically verified hyperparathyroidism . - pubmed
In 16 patients with primary or secondary ( uraemic ) hyperplasia , 11 out of 48 hyperplastic glands in the neck were identified by ultrasound . - pubmed
A parathyroid adenoma was revealed in all ( 3 ) patients with hypercalcaemic crisis . - pubmed
Enlarged parathyroid glands were correctly located in all ( 5 ) patients with adenomas and previous explorations of the neck , whereas two out of three glands were visualized by ultrasound prior to secondary explorations in 3 patients with hyperplasia associated with the multiple endocrine neoplasia syndrome type 1 . - pubmed
A nodular thyroid goitre was present in almost half of the patients with a negative ultrasonic examination of the parathyroid glands . - pubmed
We evaluated anion gap in 28 children - 18 boys and 10 girls with minimal change nephrotic syndrome during 55 separate episodes of exacerbations . - pubmed
Intracranial pressure changes in patients with head trauma during haemodialysis . - pubmed
Intracranial hypertension and acute renal failure are frequent complications in polytraumatized patients with head trauma . - pubmed
Epidermoid carcinomas were induced in hamster buccal pouches with use of 7.12 dimethylbenz [ a ] anthracene ( DMBA ) . - pubmed
In five animals that served as tumor controls ( Group 1 ) , right buccal pouches were painted with DMBA ( 0.5 % solution in mineral oil ) thrice weekly for 14 weeks . - pubmed
Histopathologically , there were also fewer sites of dysplasia , carcinoma in situ , and early invasive epidermoid carcinoma than in the tumor control animals . - pubmed
We studied 38 normal controls and 12 patients with peroxisomal diseases and found complete discrimination between the two groups . - pubmed
The effect of alimentary pectin obtained from different raw materials ( apple , tomato , cotton - wool ) on the causative agents of infectious diarrheal diseases , belonging to the genera Shigella , Salmonella , Klebsiella , Enterobacter , Proteus and Citrobacter , was studied under experimental conditions and in clinical observations . - pubmed
Contact sensitivity to Tinuvin P in mice . - pubmed
Two methods that gave minimum variation between the readings are presented here with interobserver and intraobserver reliability on 17 girls with adolescent idiopathic scoliosis . - pubmed
Phase I dose - escalation trial of iodine 131 - labeled monoclonal antibody OKB7 in patients with non - Hodgkin ' s lymphoma . - pubmed
Specific tumor visualization was noted in eight of 18 patients . - pubmed
Hematologic toxicity was observed in six of 18 patients , but was severe in only two patients . - pubmed
131I - OKB7 was safely administered to a patient in leukemic phase of NHL with prompt subsequent loss of approximately 1 kg of tumor cells from the peripheral blood without associated tumor lysis syndrome . - pubmed
Antidepressant response to sleep deprivation as a function of time into depressive episode in rapidly cycling bipolar patients . - pubmed
Three patients with treatment - resistant rapidly cycling bipolar disorder were studied with multiple sleep deprivations ( SD ) during several depressive episodes to assess the effect of phase or duration of a depressive episode on SD response . - pubmed
In 2 subjects , the duration of antidepressant response to SD increased linearly as time into episode increased . - pubmed
These results suggest that the neurobiological substrates underlying depression may change over the course of an episode , resulting in an increased responsivity to sleep deprivation later compared with earlier in the course of an episode in rapidly cycling patients . - pubmed
The generalizability of these findings to unipolar patients remains to be explored . - pubmed
PURPOSE : The outcome of radical external beam radiation therapy for 26 consecutive patients with invasive carcinoma of the penis treated between 1970 and 1985 was assessed to test the efficacy , and side effects of such treatment . - pubmed
METHODS AND MATERIAL : A retrospective review of 26 patients with invasive carcinoma of the penis and 11 patients with carcinoma in - situ of the penis , treated at the Princess Margaret Hospital between 1970 and 1985 , was performed . - pubmed
RESULTS : The 5 - year overall actuarial survival for patients with invasive cancers was 62 % ( + /- 10 ) and the cause - specific survival was 69 % ( + /- 9 ) . - pubmed
All patients with carcinoma in - situ achieved a complete response and , with follow - up ranging from 1 to 14 years , none recurred . - pubmed
CONCLUSION : We conclude that radiation therapy with surgery reserved for the management of local recurrence is an effective first line treatment for patients with carcinoma of the penis . - pubmed
We have investigated the effect of mild hyperthermia ( 42 degrees C ) on the cytotoxic activity of a 1 h melphalan exposure in human melanoma cell lines . - pubmed
Weaver mice have a severe hypoplasia of the cerebellum with an almost complete loss of the midline granule cells . - pubmed
Helicobacter pylori and congestive gastropathy . - pubmed
This study evaluates the prevalence and significance of Helicobacter pylori ( H . - pubmed
118 patients were selected , i. e. 90 patients with portal hypertension ( 66 males , 24 females , mean age 49.1 + /- 2.1 years ) and 28 noncirrhotic patients with nonulcerative dyspepsia as a control group ( twelve males , 16 females , mean age 47.6 + /- 2.8 years ) . - pubmed
We found also that the presence and severity of congestive gastropathy is independent of the H. - pubmed
SUBJECTS : Three hundred patients undergoing abdominal , thoracic , or vascular surgical procedures who either had documented coronary artery disease or were at high risk for coronary disease . - pubmed
CONCLUSION : In patients with cardiac risk factors who are undergoing noncardiac surgery , the perioperative maintenance of normothermia is associated with a reduced incidence of morbid cardiac events and ventricular tachycardia . - pubmed
Resting state patterns of regional glucose metabolism in idiopathic depressed patients , changes in metabolism with antidepressant treatment , and blood flow changes with induced sadness in healthy subjects were used to test and refine this hypothesis . - pubmed
HIV - related NP impairment was generally mild , especially in the medically asymptomatic stage of infection , and most often affected attention , speed of information processing , and learning efficiency ; this pattern is consistent with earliest involvement of subcortical or frontostriatal brain systems . - pubmed
METHODS : Twenty - one healthy subjects , 58 patients with acute pancreatitis , and 20 patients with nonpancreatic acute abdomen were studied . - pubmed
Characterization of the mitochondrial DNA abnormalities in the skeletal muscle of patients with inclusion body myositis . - pubmed
Twenty - two HIV+ patients with encephalitis were studied . - pubmed
Of these , 7 had meningoencephalitis due to Toxoplasma gondii ( MT ) and 15 due to Trypanosoma cruzi ( MC ) . - pubmed
We found that focal necrotizing encephalitis due to Toxoplasma involved the cerebral cortex and the basal ganglia , whereas lesions due to Trypanosoma cruzi were centered in the white matter , sometimes extending into the cortex . - pubmed
A study has been carried out on the action of cytoskeleton and metabolic inhibitors on intracellular multiplication in HeLa cells of a virulent strain of Legionella pneumophila serogroup 6 . - pubmed
We describe a 9 - year - old white boy with systemic juvenile rheumatoid arthritis ( JRA ) who developed pancytopenia and hypersplenism at the age of 13 years . - pubmed
In 67 borderline psychiatric patients suffering from schizotypal / slowly developing schizophrenic disorders and 18 patients suffering from cyclothymia , the factor structure of the period ( interval - amplitude ) parameters of the EEG proved to be similar to that obtained in normal subjects during mental activity and reported in part I ( Lazarev , Int . - pubmed
This report provides the first evidence for the presence of vascular apoptosis in myocardial infarction induced in rats by occluding the coronary artery for 7 weeks . - pubmed
Squamous cell carcinoma , not basal cell carcinoma , is the most common cancer in humans . - pubmed
HUC were isolated from the ureters or renal pelves of two nephrectomized adults and of two children with ureteropelvic junction stenosis and cultured under serum - free conditions . - pubmed
BACKGROUND : While small improvements in outcome have occurred for patients with locally advanced non - small cell lung cancer ( NSCLC ) , 5 - year survival results remain low , ranging from 5 % to 20 % . - pubmed
METHODS : Trials investigating innovative treatment strategies for patients with locally advanced and/or unresectable NSCLC are reviewed , including altered radiation fractionation schema , conformal 3 - dimensional radiotherapy , and combined chemoradiotherapy regimens . - pubmed
CONCLUSIONS : Ongoing investigations are warranted to combat both local - regional and systemic failures for patients with locally advanced NSCLC . - pubmed
Salviae Miltiorrhizae Radix has exhibited a beneficial effect in the improvement of renal failure . - pubmed
The prevalence of different African horsesickness virus serotypes in the Onderstepoort area near Pretoria , during an outbreak of African horsesickness in South Africa in 1995/1996 . - pubmed
OBJECTIVE : To assess the efficacy of acarbose monotherapy during 12 - weeks treatment on the fasting glycemic level , lipid and lipoproteins profiles , in patients with type 2 diabetes mellitus . - pubmed
METHODS : Forty - four patients ( 36 men and 8 women , mean age 55.09 + /- 1.72 years ) were included of whom 25 ( 56.81 % ) patients were previously treated with diet alone , 11(25 % ) with diet and glibenclamide , 5(11.36 % ) with diet and gliclazide , and 3(6.81 % ) with diet and chlorpropamide , more than at least 3 months known duration of diagnosed type 2 diabetes , body mass index ( BMI ) 23.69 + /- 0.49 kg / m2 , were insufficiently controlled on diet alone , or diet plus sulfonylureas , were studied . - pubmed
Almost , all adverse experiences , as reported by patients on acarbose , were related to the digestive system and included diarrhea , flatulence , bloating and nausea . - pubmed
Parametric control of fingertip forces during precision grip lifts in children with DCD ( developmental coordination disorder ) and DAMP ( deficits in attention motor control and perception ) . - pubmed
Twenty boys with developmental coordination disorder ( DCD ) , 11 of whom had associated attention deficit disorder ( ADD ) , were compared with an age - matched control group of 12 boys to examine mechanisms that adapt the grip force at the digit - object interface in a precision grip task . - pubmed
In a clinical series , amniotic membrane patches of the ocular surface were performed in 20 eyes of 20 patients with persistent corneal epithelial defects , or as a prophylactic measure after corneal limbal transplantation . - pubmed
The effects of muscle activation on postural stability in diabetes mellitus patients with cutaneous sensory deficit in the foot . - pubmed
Activity of the lower leg muscles in response to an unexpected disturbance to upright standing was studied in diabetic patients and non - diabetic matched controls . - pubmed
The diabetic individuals were classified into two groups : diabetic patients with normal cutaneous sensitivity in the foot ( n=27 ) and patients with cutaneous sensory deficit ( n=23 ) . - pubmed
The results suggest that the inability to generate a neuromuscular response with consistent temporal patterning is a contributing factor to greater postural sway observed in diabetic patients with cutaneous sensory deficit in the foot . - pubmed
The impact of this problem in the routine treatment of patients with human immunodeficiency virus infection is poorly defined . - pubmed
OBJECTIVES : Our aim was to determine what clinical features are associated with hepatotoxicity in human immunodeficiency virus - infected patients receiving antiretroviral therapy . - pubmed
METHODS : Consecutive patients in a primary care - based human immunodeficiency virus clinic were evaluated for hepatotoxicity . - pubmed
In this report , we describe patients with hypothyroidism who were receiving therapy for multi - drug - resistant tuberculosis , tuberculosis namely , resistant to at least isoniazid ( INH ) and rifampicin ( RFP ) , with a regimen that contained PAS . - pubmed
CONCLUSIONS : These data indicate that aging attenuates the vestibulosympathetic reflex in humans and may contribute to the increased prevalence of orthostatic hypotension with age . - pubmed
Heparin - induced platelet reactivity was studied in a subgroup of 86 patients . - pubmed
Antibodies were detected in 3 - 6 % of hemodialysis patients and antibody levels correlated to blood access thrombosis and change of access ( p<0.05 ) . - pubmed
An unexpected finding was that of increased heparin - induced platelet reactivity in 36 % of the control group of 24 uremic patients prior to dialysis or exposure to heparin . - pubmed
PARTICIPANTS : Optotype thresholds determination in three normal subjects and testing on 30 consecutive patients with unclear visual acuity loss . - pubmed
A pocket chart was tested in a masked manner on 30 consecutive patients referred because of unclear visual acuity loss . - pubmed
Ten percent ( 3 of 30 ) of the patients referred because of unclear visual acuity loss had to be excluded , because their diagnosis remained unclear . - pubmed
All patients ( 16 of 16 ) with organic visual loss saw all optotypes sizes . - pubmed
The first group ( n=6 ) was submitted to hysteroscopy and endometrial biopsy for metrorrhage , showing normal proliferative ( n=2 ) or secretory ( n=4 ) endometrium , the second group ( n=10 ) included patients submitted to hysterectomy for endometrial adenocarcinoma ( stages Ib - IIIb ) . - pubmed
The mean body weights of male rats receiving 50,000 or 100,000 ppm and female rats given 100,000 ppm were lower than those of controls . - pubmed
Body weights of all groups of mice were similar . - pubmed
Kidney and liver weight to body weight ratios for exposed rats and mice were greater than those for controls . - pubmed
Centrilobular hepatocellular hypertrophy was noted in male and female mice receiving 20,000 and 50,000 ppm acetone , respectively . - pubmed
The final mean body weights of rats receiving 50,000 ppm were 19%percnt ; lower than that of controls for males and 7%percnt ; lower for females . - pubmed
Liver and kidney weight to body weight ratios were increased for male and female rats receiving 20,000 ppm or greater . - pubmed
Leukocytosis and thrombocytopenia were observed at 20,000 ppm and above ( males and females ) , and reticulocytopenia and erythrocytopenia were seen at 5,000 ppm and above ( males ) . - pubmed
Splenic pigmentation ( hemosiderosis ) noted in dosed male rats was apparently related to these changes . - pubmed
The increased incidence and severity of nephropathy observed in dosed male rats were considered the most prominent chemically related findings in this study . - pubmed
The final mean body weights of dosed and control mice were similar . - pubmed
The absolute liver weight and the liver weight to body weight ratio were significantly increased for females receiving 50,000 ppm , and the absolute spleen weight and the spleen weight to body weight ratio were significantly decreased . - pubmed
Centrilobular hepatocellular hypertrophy of minimal severity was seen in 2110 female mice receiving 50,000 ppm . - pubmed
In 2002 , the reported numbers of human and animal infections increased , and the geographic range of WNV activity expanded substantially . - pubmed
These data underscore the need for intensive surveillance to detect and quantify WNV activity in areas where humans are at risk , public education to teach persons how to prevent mosquito bites , and sustained and integrated mosquito - control activities . - pubmed
A series of 10 cutaneous melanomas and 24 benign melanocytic lesions with patient records were independently examined for diagnosis confirmation and immunohistochemical expression by two dermatopathologists . - pubmed
[ Experimental study on the formation of lung metastasis in ascites cancer of mice ] . - pubmed
Haemoglobinuria among adult Nigerians due to glucose-6 - phosphate dehydrogenase deficiency with drug sensitivity . - pubmed
Bilateral occipital neuropathy as a rare complication of positioning for thyroid surgery in a morbidly obese patient . - pubmed
This is the first case report of temporary bilateral occipital neuropathy from positioning for thyroid surgery in a morbidly obese patient . - pubmed
METHODS : A 48 - year - old women with a history of depression , fibro - myalgia , asthma , sleep apnea , diabetes mellitus and morbid obesity ( 127 kg , 165 cm ) underwent 4 hours anesthesia with propofol / remifentanil without muscle relaxation for thyroid surgery . - pubmed
Pressure from fat tissue during prolonged head extension for surgery seems to be the cause in this case and should therefore be avoided whenever possible in morbidly obese patients , especially when other risk factors for neuropathy like diabetes are present . - pubmed
RESULTS : Of the 155 patients , 144 fitted the clinical diagnosis of tuberculosis , and 112 of them were culture positive for M tuberculosis . - pubmed
To determine whether there might be a biologic interaction between these two pathogens in vivo , we infected mice with Mycobacterium tuberculosis and then with a non - lethal strain of Plasmodium yoelii eight weeks later . - pubmed
tuberculosis simulate the equilibrium between pathogen and host thought to exist in human latent infection . - pubmed
RESULTS : The nerve was saved from peroperation damage in two patients with nervus laryngeus recurrens . - pubmed
The third patient with this deviation ended up with permanent unilateral paralysis of the nerve , which indicated erroneous evaluation of nerve branches . - pubmed
RESULTS : All animals lacking both activities survived to the hepatotoxic administration . - pubmed
We analyzed the prognosis of 52 patients with liver metastases from colorectal cancer treated with MCT as the first radical therapy . - pubmed
Transformation of alternan - producing strains of Leuconostoc by electroporation . - pubmed
METHODS : The results of treatment of patients with symptomatic solitary non - parasitic hepatic cysts treated between 1995 and 2000 were reviewed . - pubmed
Five patients were treated by laparoscopic fenestration ab initio as they also required a cholecystectomy because of gallstones . - pubmed
Biopsy specimens were taken from early affected scalp lesions and paired with samples from clinically unaffected areas in the same patient . - pubmed
CONCLUSION : A descriptive , standardized histopathologic reporting of follicular architecture , type , location , and extent of the inflammatory infiltrate , and presence or absence of sebaceous glands , may be of greatest value in guiding the treatment of patients with primary cicatricial alopecias . - pubmed
Inhibitory effects of idoxifene on hepatic fibrosis in rats . - pubmed
METHODS : Hepatic fibrosis was induced by dimethylnitrosamine ( DMN ) in male rats . - pubmed
RESULTS : Idoxifene could markedly suppress DMN - induced hepatic fibrosis in male rats . - pubmed
CONCLUSION : Idoxifene showed inhibitory action on hepatic fibrosis in male rats . - pubmed
[ Nosohusial infection by Pseudomonas putida ] . - pubmed
[ Effects of different levels of positive end expiratory pressure on lung recruitment and hemodynamics after sustained inflation in acute respiratory distress syndrome in sheep ] . - pubmed
OBJECTIVE : To study the effects of different levels of positive end expiratory pressure ( PEEP ) on recruitment and hemodynamics after sustained inflation in acute respiratory distress syndrome ( ARDS ) in sheep . - pubmed
METHODS : Twelve adult sheep were anaesthetized and ARDS was induced by lung lavage with warm normal saline . - pubmed
For successful CPR of trauma patients , a minimal intravascular volume status and management of hypoxia are essential . - pubmed
Despite bad prognosis , CPR in trauma patients may be successful in select cases . - pubmed
BACKGROUND : Elective colonoscopy is used increasingly to screen at risk patients for colonic malignancy . - pubmed
Gamma - Hydroxybutyrate ( GHB ) , gamma - butyrolactone ( GBL ) , and 1,4 - butanediol ( 1,4 - BD ) reduce the volume of cerebral infarction in rodent transient middle cerebral artery occlusion . - pubmed
We examined the potential neuroprotective effect of GHB and its chemical precursors , gamma - butyrolactone ( GBL ) and 1,4 - butanediol ( 1,4 - BD ) , in the rodent ischemic stroke model by intraluminal filament middle cerebral artery occlusion ( MCAO ) . - pubmed
Adult male Sprague - Dawley rats underwent transient left - sided MCAO and received intraperitoneal treatment with 300 mg / kg of GHB , GBL , 1,4 - BD , or control vehicle given at 30 min before , as well as 180 and 360 min after the onset of ischemia . - pubmed
In transient MCAO , the mean volume of infarction for control rats was 464.4 + /- 17.9 cu.mm versus 273.6 + /- 53.1 , 233.3 + /- 44.7 , and 275.4 + /- 39.9 cu.mm for rats treated with 1,4 - BD ( P & lt ; 0.05 ) , GBL ( P & lt ; 0.05 ) , and GHB ( P & lt ; 0.05 ) , respectively . - pubmed
We conclude that GHB , GBL , and 1,4 - BD protect against rat focal cerebral ischemia from transient MCAO . - pubmed
Quantitative sensory testing for spinal cord stimulation in patients with chronic neuropathic pain . - pubmed
PARTICIPANTS : Thirteen patients with radicular leg pain due to failed back surgery syndrome ( FBSS ) or leg pain due to complex regional pain syndrome ( CRPS ) who were candidates for SCS . - pubmed
Selective loss of dentate hilar interneurons contributes to reduced synaptic inhibition of granule cells in an electrical stimulation - based animal model of temporal lobe epilepsy . - pubmed
Neuropeptide - containing hippocampal interneurons and dentate granule cell inhibition were investigated at different periods following electrical stimulation - induced , self - sustaining status epilepticus ( SE ) in rats . - pubmed
This loss may contribute to the reduced GABAergic synaptic inhibition of granule cells in epileptic animals . - pubmed
In secondary and sometimes in early latent syphilis , antibodies reacted with high numbers of antigenic proteins of T. - pubmed
CONCLUSION : The 1 - year incidence of TMJ pain and/or dysfunction was high among 1st - year university students . - pubmed
Constituents in rosemary have shown a variety of pharmacological activities for cancer chemoprevention and therapy in in vitro and in vivo models . - pubmed
In order to further explore the chemopreventive properties of crude extracts of rosemary ( Rosmarinus officinalis L ) , we studied its anti - proliferative property on several human cancer cell lines and its antioxidant and anti - inflammatory properties in vitro in a mouse RAW 264.7 macrophage / monocyte cell line . - pubmed
Our study shows that crude ethanolic rosemary extract ( RO ) has differential anti - proliferative effects on human leukemia and breast carcinoma cells . - pubmed
On the other hand , LH cases showed extensive , predominantly lytic hepatocytic necrosis , portal and hepatic vein phlebitis and morula cells in patients with a morphological background of chronic liver disease . - pubmed
Risk factors for a Blastocystis infection were drinking unboiled water , consumption of raw water plants and pig ownership . - pubmed
In conclusion , human Blastocystis was common in this village in southwest China , and different subtypes were associated with distinct transmission routes or sources of infection , and hence Blastocystis subtypes might be linked to specific environmental compartments . - pubmed
The objective was to evaluate the efficacy and toxicity of leucovorin plus 5 - fluorouracil combined with oxaliplatin ( modified FOLFOX regimen ) every 2 weeks on previously untreated advanced colorectal cancer patients in the Chinese population . - pubmed
Toxicities were mild : five patients ( 9.8 % ) reported grade 3 - 4 neutropenia , 33 patients ( 64.8 % ) experienced grade 1 - 3 neurotoxicity and only six patients ( 11.8 % ) experienced grade 3 neurotoxicity . - pubmed
The leucovorin plus 5 - fluorouracil combined with oxaliplatin ( modified FOLFOX ) regimen is active and well tolerated in patients with previously untreated advanced colorectal cancer in the Chinese population . - pubmed
Characterization of Trypanosoma cruzi isolated from humans , vectors , and animal reservoirs following an outbreak of acute human Chagas disease in Santa Catarina State , Brazil . - pubmed
During March 2005 , 24 cases of acute human Chagas disease were detected in Santa Catarina State , southern Brazil , all of them related to the ingestion of Trypanosoma cruzi - contaminated sugar cane juice . - pubmed
Considering that mixed strains ( TcI / TcII ) were isolated from triatomines in an area without active vectorial transmission to humans and that all strains isolated from humans belong to the TcII group , our results show that T. - pubmed
OBJECTIVE : To identify the complications and possible associated factors observed in patients with suspected prostate cancer undergoing transrectal ultrasound - guided ( TRUS ) biopsy . - pubmed
The etiologies were heat injury of the lateral malleolus in one patient and skin necrosis over the Achilles tendon attachment site in three patients due to displaced calcaneal fracture , pyogenic tendinitis of the Achilles tendon , and vascular insufficiency of the wound after Achilles tendon surgery in a patient with Werner syndrome , respectively . - pubmed
Postoperative complications included delayed wound healing in one patient and transient restriction of ankle motion in another patient . - pubmed
Hospital - acquired methicillin - resistant Staphylococcus aureus ( MRSA ) strains are no longer limited to acute - care hospitals but have now spread to other healthcare settings such as long - term - care facilities ( LTCFs ) , in most of which they are endemic . - pubmed
Running activity increased gradually and was high in spontaneously hypertensive rats ( SHR ) and Sprague - Dawley rats , while low in Wistar rats . - pubmed
Patients with a clinical and radiographic diagnosis of CAP were enrolled . - pubmed
We report on two FLSpCC patients treated with wide local excision and mastectomy associated with axillary lymph node dissection . - pubmed
A comparative analysis found the vascular density in free liver cyst walls was greater in mice than in humans . - pubmed
The authors describe a patient with drop foot who had a compressed common peroneal nerve caused by posterior fibular head dysfunction . - pubmed
For HIV positive patients , 11.7 % had cerebral toxoplasmosis . - pubmed
Twenty - one patients presenting toxoplasmic retinochoroiditis were treated by subconjonctival injections of clindamycin and systemic corticotherapy at a dose of 1 mg / kg per day . - pubmed
Predictors of the recurrence of hepatic encephalopathy in lactulose - treated patients . - pubmed
METHODS : Patients with cirrhosis who were initiated on lactulose after an index hepatic encephalopathy episode in a liver - transplant centre were retrospectively reviewed . - pubmed
Patients with / without hepatic encephalopathy recurrence were compared , and predictors of recurrence were analysed . - pubmed
RESULTS : A total of 137 patients with cirrhosis ( age 55 + /- 6years , MELD 17 + /- 7 ) who were initiated on lactulose after the index hepatic encephalopathy episode were included . - pubmed
Of these , 103 patients developed recurrent hepatic encephalopathy 9 + /- 1 months after their index episode ; 39 ( 38 % ) of these were not adherent on lactulose , 56 ( 54 % ) were adherent and 8 ( 8 % ) had lactulose - associated dehydration leading to recurrence . - pubmed
Recurrent hepatic encephalopathy precipitants in lactulose - adherent patients were sepsis ( 19 % ) , GI bleeding ( 15 % ) , hyponatremia ( 4 % ) and TIPS ( 7 % ) . - pubmed
Glycemic control and the risk of death in 1,484 patients receiving maintenance hemodialysis . - pubmed
BACKGROUND : It is controversial whether tighter glycemic control is associated with better clinical outcomes in people with kidney failure . - pubmed
How pDCs control peripheral immunetolerance and local parenchymal immune response and contribute to the altered immunoregulation in autoimmune disorders in humans is poorly understood . - pubmed
To evaluate the potential immunoregulatory role of these two types of pDCs in multiple sclerosis ( MS ) and other human autoimmune disorders ( myasthenia gravis ) , we studied the phenotype and regulatory function of pDCs isolated from clinically stable , untreated patients with MS ( n = 16 ) . - pubmed
Patients with MS showed a reversed ratio of pDC1 / pDC2 in peripheral blood ( 4.4:1 in healthy controls , 0.69:1 in MS ) , a phenomenon not observed in the other autoimmune disorders . - pubmed
Our data offer a plausible explanation for the disturbed immune tolerance in MS patients and provide evidence that immunomodulatory therapy acts at the level of reconstituting homeostasis of pDC , thus reconstituting the disturbed balance . - pubmed
In conclusion , ezetimibe 10mg / day add - on therapy may be safe and effective for treating dislipidemia patients who have been treated with a statin . - pubmed
However , the 3 autopsy patients who were diagnosed with NHLE on the basis of their typical clinical course died of complications . - pubmed
After 24 months : 1 BMS , 2 SES patients died ; 0 BMS , 0 SES infarction ; 0 BMS , 0 SES stent thrombosis and 3 BMS , 0 SES TVR between six and 24 months . - pubmed
Between six and 24 months , neither stent thrombosis occurred , nor repeat revascularisation was required in patients who received a SES . - pubmed
PURPOSE : The aim of this study was to evaluate treatment results in our hypopharyngeal cancer patients . - pubmed
PATIENTS AND METHODS : A total of three hundred and ninety five hypopharyngeal cancer patients received radical treatment at our hospital ; 96 % were male . - pubmed
All patients received a CT scan or MRI for tumor staging before treatment . - pubmed
There was no significant difference in overall and disease - specific survival rates between patients who received radical surgery first and those who received OPIT . - pubmed
Thirty - seven patients developed a second malignancy , with an annual incidence of 4.6 % . - pubmed
CONCLUSIONS : There was no survival difference between OPIT and radical surgery in hypopharyngeal cancer patients at our hospital . - pubmed
To discover how these changes are reflected at the level of gene expression , we used a subtractive transcription - based amplification of mRNA procedure to identify novel genes that have altered expression levels in the brains of Alzheimer ' s disease ( AD ) patients . - pubmed
METHODS : From September 2007 to September 2008 , 60 outpatients with stenosing tenovaginitis of flexor digitorum were randomized divided into the treatment group and the control group , 30 cases in each group . - pubmed
The patients were followed up for 6 months , and the relief of moving - pain , tender - pain , stretching - pain and resist - ing -- pain were observed respectively . - pubmed
Compared with the controls , the patients given the combination were less likely to have headaches after 7 days ( P = 0 038 ) , tended to have headaches that cleared quicker ( P = 0 010 ) , and received fewer doses of acetaminophen ( P = 0 036 ) . - pubmed
Antibody recognition of porcine circovirus type 2 capsid protein epitopes after vaccination , infection , and disease . - pubmed
Baculovirus - based vaccines that express only ORF2 are protective against clinical disease following experimental challenge or natural infection . - pubmed
A retrospective case series of bipolar patients with adjunctive carbamazepine in long - term lithium treatment : evaluation of the effectiveness . - pubmed
From these results , more than 20 % of clinically normal and 97 % of diarrheic rabbits were positive for single or concurrent infection of three pathogens . - pubmed
METHODS : We reviewed 36 schwannomas from 35 patients who underwent surgical excision of schwannomas arising from the extremities . - pubmed
The duration of symptoms , maximum tumor diameter and site of occurrence were compared between patients with the three grades of deficit . - pubmed
RESULTS : In total , 22 patients developed no sensory changes following enucleation of schwannoma or only temporary and minor changes that had fully resolved within 6 months . - pubmed
Ten patients developed new neurological deficits following surgery that took longer than 6 months to resolve . - pubmed
Four patients experienced new motor deficits or paresthesia following operation that had still not recovered at the final follow - up , all of whom underwent enucleation using the extra - capsular technique . - pubmed
Patient age , duration of symptoms , maximum diameter of the tumor and site of occurrence did not influence the neurological deficit following enucleation of schwannoma . - pubmed
Thorough pre - operative counseling of patients to inform them of the potential occurrence of neurological deficit is important . - pubmed
Endoscopic extraperitoneal radical prostatectomy ( EERPE ) is a well - established and standardized technique for treating patients with localized prostate cancer . - pubmed
BACKGROUND : Age - specific comparisons of influenza and respiratory syncytial virus ( RSV ) hospitalization rates can inform prevention efforts , including vaccine development plans . - pubmed
For each state and age group , we estimated the contribution of influenza and RSV to hospitalizations for respiratory and circulatory disease by using negative binomial regression models that incorporated weekly influenza and RSV surveillance data as covariates . - pubmed
Age - standardized annual rates per 100000 person - years varied substantially for influenza ( 33 - 100 ) but less for RSV ( 42 - 77 ) . - pubmed
In recent years , the use of live microorganisms , such as viruses and bacteria , has gained substantial research and clinical interest in both detection and therapy of cancer . - pubmed
CASE PRESENTATION : Case 1 was a 68 - year - old man who was shown on radiography to have left lower calyx calculi ( 19 x 15 mm , 7 x 5 mm , and 7 x 3 mm ) in horseshoe kidney . - pubmed
Case 2 was a 36 - year - old woman shown on radiography to have a left lower calyx calculus ( 10 x 8 mm ) in horseshoe kidney . - pubmed
RECENT FINDINGS : It is becoming apparent that the skin inflammation alone has implications for systemic and malignancy risk in dermatomyositis patients , and that there may be several pathogenic similarities between muscle and skin inflammation in dermatomyositis . - pubmed
SUMMARY : A more careful description and classification of skin disease in dermatomyositis may allow the clinician to predict more accurately which patients will be at higher risk for cancer , lung disease , or muscle inflammation . - pubmed
MATERIAL AND METHODS : The trial enrolled 83 patients ( 42 - 51 % males , 41 - 49 % females , mean age 46.7 years ) with stage II - IV CKD of non - diabetic origin . - pubmed
RESULTS : LVH was detected in 31 ( 37.3 % ) of 83 patients . - pubmed
Concentric remodeling , concentric LVH , eccentric LVH were detected in 31.3 , 19.3 and 18.1 % patients , respectively . - pubmed
CONCLUSION : Patients with renal dysfunction develop LVH of different geometric model associated with both conventional and renal risk factors even at early stages of CKD . - pubmed
Due to their effectiveness as antifungal agents , three semisynthetic derivatives have been developed and approved for treatment of human invasive candidiasis . - pubmed
A comparison of coronary angiographic findings in patients with and without prior cerebral infarction . - pubmed
Previous studies based on coronary angiography or computed tomography coronary angiography have demonstrated a high prevalence of coronary stenosis in patients with cerebral infarction and no prior history of coronary artery disease ( CAD ) . - pubmed
The purpose of the present study was to compare the coronary angiographic findings of patients with prior cerebral infarction with those of patients with no prior cerebral infarction . - pubmed
Consecutive patients ( n = 126 ) who underwent a first coronary angiography for suspected CAD but had no prior history of CAD were classified into 2 groups , those with a clinical history of cerebral infarction ( cerebral infarction group ) and those without a clinical history of cerebral infarction ( noncerebral infarction group ) . - pubmed
Thirty - four of 78 patients ( 44 % ) with coronary stenosis did not have angina symptoms . - pubmed
Extracorporeal lung support in patients with chronic obstructive pulmonary disease . - pubmed
Non - sex cord - stromal ovarian tumors frequently produce and secrete estrogen in postmenopausal women : impact on bone metabolism and abnormal endometrial histology . - pubmed
OBJECTIVE : We investigated whether the estrogen released from non - sex cord - stromal ovarian tumors has biological effects on bone and endometrial tissue in postmenopausal women . - pubmed
Histological examinations of the endometrium were carried out in the 75 patients with non - sex cord - stromal ovarian tumors . - pubmed
Five ( 6.7 % ) of 75 patients with non - sex cord - stromal ovarian tumors displayed abnormal endometrial histology , including 4 patients with grade 1 endometrioid cancer . - pubmed
15 patients had multiple stones , 10 pyelocalicial , 10 pelvic larger than 2 cm , 2 in horseshoe kidneys and 3 staghorn stones . - pubmed
Biochemical outcomes for patients with intermediate risk prostate cancer treated with I-125 interstitial brachytherapy monotherapy . - pubmed
BACKGROUND : The most common bariatric surgery , Roux - en - Y gastric bypass , leads to glycemia normalization in most patients long before there is any appreciable weight loss . - pubmed
In vitro and in vivo anti - tumour effects of MPT0B014 , a novel derivative aroylquinoline , and in combination with erlotinib in human non - small - cell lung cancer cells . - pubmed
EXPERIMENTAL APPROACH : Cytotoxicity in human NSCLC cell lines was assessed by sulforhodamine B and 3 -( 4,5 - dimethylthiazol-2 - yl )- 2,5 - diphenyltetrazolium bromide assays . - pubmed
[ Dengue virus & amp ; co : are mosquito - borne viral diseases on the rise ? ] - pubmed
Postpartal subclinical endometritis alters transcriptome profiles in liver and adipose tissue of dairy cows . - pubmed
Transcriptome alterations in liver and adipose tissue of cows with subclinical endometritis ( SCE ) at 29 d postpartum were evaluated . - pubmed
RESULTS : Thirty - four out of 504 patients ( 6.8 % ) had incidental prostate cancer with a mean age of 70.3 years . - pubmed
Biochemical recurrence occurred in 3 patients but no prostate cancer - related death during the follow - up . - pubmed
BACKGROUND : The National Institutes of Health.funded Trial to Assess Chelation Therapy ( TACT ) randomized 1708 stablecoronary disease patients aged .50 years who were .6 months post.myocardial infarction ( 2003.2010 ) to 40 infusions ofa multicomponent EDTA chelation solution or placebo . - pubmed
CONCLUSIONS : In stable , predominantly asymptomatic coronary disease patients with a history of myocardial infarction , EDTA chelation therapy did not have a detectable effect on QOL during 2 years of follow - up . - pubmed
A bone failure was created in left parietal bone of adult male mice . - pubmed
After exclusion due to death or infection , thirty - eight animals were evaluated ( BT=5 ; BM=6 ; BA=6 ; TCP=7 ; MDM=3 ; ALG=6 ; BAG=5 ) . - pubmed
UNLABELLED : Human papillomaviruses ( HPVs ) are small DNA viruses causally associated with benign warts and multiple cancers , including cervical and head - and - neck cancers . - pubmed
While the vast majority of people are exposed to HPV , most instances of infection are cleared naturally . - pubmed
IMPORTANCE : Human papillomaviruses ( HPVs ) are highly prevalent and potent human pathogens that cause & gt;5 % of all human cancers , including cervical and head - and - neck cancers . - pubmed
While the majority of people become infected with HPV , only 10 to 20 % of infections are established as persistent infections . - pubmed
Secondary endpoints included the number of patients in whom the oral nutrition protocol was implemented successfully , as well as the number and type of postoperative complications . - pubmed
Up to 10 % of patients with a benign stricture are refractory to pneumatic dilatation and may benefit from biodegradable stent ( BD ) insertion . - pubmed
Mean dysphagia scores improved from 2.65 to 1.00 ( p value & lt;0.001 ) in benign disease and from 3.27 to 1.36 ( p value & lt;0.001 ) in patients with malignant disease . - pubmed
Distribution and treatment of clavicular fractures in monotrauma and polytrauma patients . - pubmed
BACKGROUND : Although extensive research for the optimal treatment of clavicle fractures has been performed , comparative studies between monotrauma and polytrauma patients are lacking . - pubmed
OBJECTIVE : To compare fracture distribution and treatment in monotrauma and polytrauma patients with a clavicle fracture . - pubmed
Monotrauma patients sustained only a clavicle fracture or a clavicle fracture plus a minor abrasion , hematoma , or superficial skin lesion leading to an Injury Severity Score ( ISS ) of 4 or 5 respectively . - pubmed
RESULTS : 154 monotrauma and 155 polytrauma patients with a clavicle fracture were identified . - pubmed
Monotrauma patients had a higher incidence of Type IIB fractures ( displaced midshaft ) compared to polytrauma patients ( P = 0.002 ) . - pubmed
CONCLUSIONS : Monotrauma patients had a higher incidence of displaced midshaft clavicle fractures compared to polytrauma patients , and monotrauma patients with displaced midshaft clavicle fractures were treated operatively more frequently . - pubmed
Diminished weight gain , impaired fat absorption , and elevated steatorrhea occurred in KO mice after instituting high - fat diet . - pubmed
CONCLUSION : After SBR , KO mice display an inefficient intestinal absorption profile with perturbed macronutrient transporter expression , impaired fat absorption , and slower postoperative weight gain . - pubmed
Posttraumatic seizures and epilepsy in adult rats after controlled cortical impact . - pubmed
Posttraumatic epilepsy ( PTE ) has been modeled with different techniques of experimental traumatic brain injury ( TBI ) using mice and rats at various ages . - pubmed
We hypothesized that the technique of controlled cortical impact ( CCI ) could be used to establish a model of PTE in young adult rats . - pubmed
Provoked class 3 - 5 seizures were recorded by video monitoring in 7/57 ( 12.3 % ) animals in the week immediately following CCI of the right parietal cortex ; none of the 7 animals demonstrated subsequent spontaneous convulsive seizures . - pubmed
Monitoring with video and/or video - EEG was performed on 128 animals at various time points 8 - 619 days beyond one week following CCI during which 26 ( 20.3 % ) demonstrated nonconvulsive or convulsive epileptic seizures . - pubmed
Nonconvulsive epileptic seizures of & gt;10s were demonstrated in 7/40 ( 17.5 % ) animals implanted with 2 or 3 depth electrodes and usually characterized by an initial change in behavior ( head raising or animal alerting ) followed by motor arrest during an ictal discharge that consisted of high - amplitude spikes or spike - waves with frequencies ranging between 1 and 2Hz class 3 - 5 epileptic seizures were recorded by video monitoring in 17/88 ( 19 % ) and by video - EEG in 2/40 ( 5 % ) CCI - injured animals . - pubmed
These results indicate that the CCI model of TBI in adult rats can be used to study the structure - function relationships that underlie epileptogenesis and PTE . - pubmed
PATIENTS AND METHODS : In all , 1146 adult patients with renal or ureteric stones were treated at one urological centre using the latest model of the Modularis Vario lithotripter . - pubmed
RESULTS : Between May 2007 and November 2009 , 698 patients with renal stones and 448 with ureteric stones underwent extracorporeal shock - wave lithotripsy ( ESWL ) . - pubmed
After 3 months , the success rate defined as the patient being stone - free or with residual fragments of & lt;4 mm ; for renal stones the rate was 91.1 % , with a 6.9 % complication rate in the form of steinstrasse and severe renal colic . - pubmed
Severe OHSS can occur in PCOS patients even after using a segmented approach i.e. - pubmed
Patients at risk of OHSS should be closely monitored following ovum pickup even when an agonist trigger has been given , for early detection and management . - pubmed
The goal of this article is to convey an appreciation of these disorders because their recognition can benefit patients tremendously , as inflammatory lesions of the pancreas can be mass - forming , giving rise to pseudotumors , and leading to surgical resection that may otherwise be unnecessary . - pubmed
OBJECTIVE : To examine the incidence of headache symptoms consistent with migraine and tension - type headache ( TTH ) in children with anxiety disorders . - pubmed
METHOD : Parents of children with anxiety disorders ( n=27 ) and children without anxiety disorders ( n=36 ) completed a headache questionnaire based on the International Classification of Headache Disorders ( 2nd edition ) criteria . - pubmed
RESULTS : Children with anxiety disorders had a higher incidence of headache symptoms consistent with migraine and TTH compared to children without anxiety disorders . - pubmed
Girls with anxiety disorders and children with separation anxiety disorder had a higher incidence of headaches compared to girls without anxiety disorders and children with other anxiety disorders respectively . - pubmed
Children with anxiety disorders and headaches had higher self - reported anxiety symptom severity compared to children with anxiety disorders without headaches and children without anxiety disorders . - pubmed
Spontaneous flexor tendon rupture due to an insufficiency fracture of the hamate hook in a patient with systemic lupus erythematosus : A case report . - pubmed
CASE PRESENTATION : A 57 - year - old woman was diagnosed with SLE 22 years ago and being treated with oral prednisolone . - pubmed
CONCLUSION : When we encounter a case of spontaneous flexor tendon rupture in a patient with systemic disease such as SLE or long - term steroid use , attention should be paid to the state of the carpal bones and joints as they sometimes accompany unexpected causes . - pubmed
Partial characterization of bacteriocin - like compounds from two strains of Bacillus cereus with biological activity against Paenibacillus larvae , the causal agent of American Foulbrood disease . - pubmed
American Foulbrood ( AFB ) , caused by the spore - forming Gram - positive bacterium Paenibacillus larvae , is the most severe bacterial disease affecting honeybees worldwide . - pubmed
The most significant findings of this study are the characterization of bacteriocin - like compounds ( BLIS ) obtained from two strains of Bacillus cereus isolated from honey . - pubmed
Both BLIS have a narrow activity range and highly inhibit the growth of Paenibacillus larvae , the causal agent of American Foulbrood disease of honey bees . - pubmed
Disbalance of calcium regulation - related genes in broiler hearts induced by selenium deficiency . - pubmed
Our objective was to investigate the effects of Se deficiency on Ca regulation - related genes in broiler hearts . - pubmed
In conclusion , the results demonstrated that Se deficiency might cause heart injury via modulating the Ca - related pathway genes , and then induce Ca2 + overload in the heart of broilers . - pubmed
Utility of plain radiographs and MRI in cervical spine clearance in symptomatic non - obtunded pediatric patients without high - impact trauma . - pubmed
Currently , there is virtually no literature regarding imaging and management of symptomatic pediatric patients who present with cervical spine trauma without high - impact mechanism . - pubmed
This study aims to establish an optimal imaging strategy for this subgroup of trauma patients . - pubmed
METHODS : We performed a retrospective review of pediatric patients ( aged below 18 years ) who were admitted to Monash Medical Centre , Melbourne , Australia between July 2011 and June 2015 , who did not suffer a high - impact trauma but were symptomatic for cervical spine injury following cervical trauma . - pubmed
MRI was able to detect 4 cases of ligamentous injury , which were not seen in CSS imaging and was able to facilitate cervical spine clearance in a further two patients whose CSS radiographs were abnormal . - pubmed
Veterinary radiologists who are aware of radiographic and imaging signs that result in animal suffering , abuse , or neglect ; knowledgeable in ways radiology and imaging may support cause of death determinations ; conversant in postmortem imaging ; comfortable discussing mechanisms and timing of blunt or sharp force and projectile trauma in imaging ; and prepared to identify mimics of abuse can assist court participants in understanding imaging evidence . - pubmed
Efficacy and safety of nivolumab in Japanese patients with previously untreated advanced melanoma : A phase II study . - pubmed
We carried out a single - arm , open - label , multicenter , phase II study to investigate the efficacy and safety of nivolumab in previously untreated Japanese patients with advanced melanoma . - pubmed
Treatment of HCV is the mainstay of therapy for mixed cryoglobulinemia syndrome , and newer HCV therapies with direct - acting antiviral agents have achieved great success in treating HCV infection compared with pegylated interferon alfa and ribavirin . - pubmed
We report a case of recurrent mixed cryoglobulinemia syndrome following HCV treatment with a new direct - acting antiviral agent ( sofosbuvir ) and ribavirin , in which HCV RNA was undetectable in serum , but detectable in the cryoprecipitate . - pubmed
RESULTS : Among the total 103 patients enrolled , 38 had disease complicated by multiple organ dysfunction syndrome ( MODS ) . - pubmed
Participants included 636 youth ( 338 girls , 298 boys ; X age in fourth grade = 9.95 , SD = .37 ) who completed measures assessing emotional clarity , stress responses , and depressive symptoms . - pubmed
valladaresi is a larger amoeba and although the cysts are similar in size , there is no sign of the pore - like structures described in L. - pubmed
Quantitative proteomic analysis of murine white adipose tissue for peritoneal cancer metastasis . - pubmed
Cancer metastasis risk increases in older individuals , but the mechanisms for this risk increase are unclear . - pubmed
Because adipose tissue produces signals which influence several diseases including cancer , proteomics of adipose tissue in aged and young mice may provide insight into metastatic mechanisms . - pubmed
INTRODUCTION : New treatments are required to improve clinical outcomes in patients with acute myocardial infarction ( AMI ) , for reduction of myocardial infarct ( MI ) size and preventing heart failure . - pubmed
Pharmacological and genetic manipulation of these ncRNAs has the therapeutic potential to improve clinical outcomes in AMI patients . - pubmed
Functional outcomes of inpatient rehabilitation in very elderly patients with stroke : differences across three age groups . - pubmed
Background As the population continues to age rapidly , clarifying the factors affecting the prognosis in very elderly stroke patients is essential to enhance the quality of their rehabilitation . - pubmed
Objectives To compare the functional recovery of elderly stroke patients classified into three age groups and to identify the predictors of functional recovery in the very elderly following acute inpatient rehabilitation . - pubmed
Methods Observational study : We collected data on 461 stroke patients in the neurology and neurosurgery ward and classified them into three age groups ( 65 - 74 , 75 - 84 , and & gt;= 85 years ) . - pubmed
Conclusions This study identified the factors associated with functional recovery among very elderly stroke patients . - pubmed
Effective forms of rehabilitation for very elderly stroke patients that take these factors into consideration need to be investigated . - pubmed
METHODS : We interviewed 66 patients who acknowledged sensory changes during hypo / manic states . - pubmed
RESULTS : Bipolar I patients were just as likely , if not more likely , to report suprasensory changes which typically involved enhancement of senses during hypo / manic phases and muting or blunting during depressive phases . - pubmed
Here we explore the potential of a tetraploid ( 2n = 4x = 68 ) interspecific hybrid sunflower as a perennial oilseed for use in multifunctional agricultural systems . - pubmed
A population of this novel tetraploid was obtained from crosses between the annual diploid oilseed crop Helianthus annuus ( 2n = 2x = 34 ) and the perennial hexaploid tuber crop Helianthus tuberosus ( 2n = 6x = 102 ) . - pubmed
These findings also offer insight into the mechanisms by which chromosomal aberrations form during human oogenesis and embryogenesis . - pubmed
A short - cut review was carried out to establish whether a normal gait examination can rule out cerebellar stroke in patients with acute vertigo . - pubmed
A similar pattern of processing was also evident in tissue extracts from an invasive ductal carcinoma patient . - pubmed
Combining in vivo APT MRI measurements with ex vivo histological measurements of protein concentration in a rat model of brain metastasis , we determined that the proportion of APT MRI signal originating from changes in protein concentration was approximately 66 % , with the remaining 34 % originating from changes in tumor pH. - pubmed
In a mouse model of hypopharyngeal squamous cell carcinoma ( FaDu ) , APT MRI showed that a reduction in tumor hypoxia was associated with a shift in tumor pH. - pubmed
The results of this study extend our understanding of APT MRI data and may enable the use of APT MRI to infer the pH of individual patients ' tumors as either a biomarker for therapy stratification or as a measure of therapeutic response in clinical settings . - pubmed
BACKGROUND : Over 80 % of women with X - linked adrenoleukodystrophy ( ALD ) develop spinal cord disease in adulthood for which treatment is supportive only . - pubmed
Moreover , diagnosis can be challenging in ALD women , as the most important diagnostic biomarker is normal in 15 - 20 % . - pubmed
The purpose of this single centre cross - sectional follow - up study in women with ALD was to assess whether Expanded Disability Status Scale ( EDSS ) , AMC Linear Disability Scale ( ALDS ) and Short Form ( 36 ) Health Survey ( SF-36 ) can detect disease progression and to model the effect of age and duration of symptoms on the rate of progression . - pubmed
For the pilot study we analysed plasma of 20 ALD women and 10 controls with ultra - high performance liquid chromatography coupled to high - resolution mass spectrometry , which identified 100 potential biomarker ratios with strong differentiating properties and non - overlapping data distributions between ALD women and controls . - pubmed
OBJECTIVES : Distinguishing between kidney stones and phleboliths can constitute a diagnostic challenge in patients undergoing unenhanced low - dose CT ( LDCT ) for acute flank pain . - pubmed
METHODS : Radiomics features were extracted following a semi - automatic segmentation of kidney stones and phleboliths for two independent consecutive cohorts of patients undergoing LDCT for acute flank pain . - pubmed
CONCLUSION : Radiomics and machine learning enable accurate differentiation between kidney stones and phleboliths on LDCT in patients presenting with acute flank pain . - pubmed
Humans and animals are widely and continuously exposed to DEHP , especially with respect to diet , which is associated with reproductive diseases . - pubmed
Patients undergoing AXBF bypass were significantly more likely to be treated for critical limb ischemia ( ABF bypass , 46.5 % ; AXBF bypass , 72.4 % ; HYB surgery , 51.8 % ; P & lt ; .001 ) under emergent conditions ( ABF bypass , 0.9 % ; AXBF bypass , 5.1 % ; HYB surgery , 3.6 % ; P & lt ; .001 ) . - pubmed
HYB surgery patients had significantly less pneumonia ( ABF bypass , 8.7 % ; HYB surgery , 1.6 % ; P & lt ; .001 ) , unplanned intubation ( ABF bypass , 7.7 % ; HYB surgery , 3.1 % ; P = .032 ) , cardiac arrest ( ABF bypass , 3.7 % ; HYB surgery , 0.5 % ; P = .025 ) , transfusion ( ABF bypass , 44.4 % ; HYB surgery , 18.1 % ; P & lt ; .001 ) , and composite morbidity ( ABF bypass , 55 % ; HYB surgery , 32.6 % ; P & lt ; .001 ) . - pubmed
This new approach will certainly improve patient convenience and compliance , possibly resulting in broader acceptance and improved efficacy of iloprost aerosol therapy in PAH . - pubmed
METHODS : A mouse model of primary blast - induced kidney injury was established using a custom - made explosive device . - pubmed
INCLUSION CRITERIA : Primary diagnostic studies , published in English ; comparing red flags for CES ; to Magnetic Resonance Imaging ( MRI ) as reference standard ; in humans ; older than 18 years . - pubmed
One hundred and ten paraffin - embedded tissue blocks ( 54 from multiple sclerosis patients , 56 from non - neurological controls ) were matched to the diffusion tensor sequence to obtain regional diffusivity measures . - pubmed
Five patients aged between 42 and 62 were found to have Grade 1 hepatosteatosis . - pubmed
METHODS : In this prospective single - center observational feasibility study , 30 cancer patients treated with palliative intent in an inpatient setting with an estimated life expectancy of & gt;8 weeks and & lt;12 months were provided with a smartphone including a pre - installed " Activity Monitoring " app and a sensor - equipped bracelet and monitored over a period of 12 weeks starting at discharge from hospital . - pubmed
Materials and Methods : This prospective , single - center study enrolled 530 patients ( mean age 67.6 + -9.8 years ; 396 men ) undergoing endovascular procedures between August 2016 and July 2018 for chronic PAD . - pubmed
METHODS : Using total RNA from human uterus adenocarcinoma and non - neoplastic uterus , we conducted a small RNA - sequencing experiment followed by prediction of novel miRNAs using MirDeep * software . - pubmed
CONCLUSIONS : Human tissues express an orthologue of mouse miR-1839 - 5p and , given its expression pattern , we suggest that this miRNA could be explored as a potential oncomiR or cancer marker . - pubmed
Betulin attenuated liver damage by prevention of hepatic mitochondrial dysfunction in rats with alcoholic steatohepatitis . - pubmed
The aim of this study was to evaluate the impact of liver mitochondria in hepatoprotection of betulin using a rat model of alcoholic steatohepatitis induced by ethanol administration ( 4 g / kg , intragastric ) for 8 weeks . - pubmed
The increased susceptibility of mitochondria to Ca2 + -induced permeability transition pore formation in the hepatitis group was improved in rats treated with betulin . - pubmed
In conclusion , betulin , having antioxidant properties , exerts a beneficial effect in the rat model of alcoholic steatohepatitis via prevention of liver mitochondria dysfunction , which may be attributed to the inhibition of mitochondrial permeability transition . - pubmed
Achieving sustained HCV elimination is likely to require a combination approach including early access to DAAs in acute infection and reinfection , validated and reproducible behavioural interventions and an efficacious HCV vaccine . - pubmed
RESULTS : The pain Scale analysis showed that patients in the RME group suffered from a significantly higher level of pain than those in the LEAF group ( 88.6 % vs 25 % , p<0.01 ) . - pubmed
Patients treated with Leaf Expander reported significantly lower pain level in the first 7 days of treatment . - pubmed
OBJECTIVE : To assess the risk of serious adverse events of infections ( SAEI ) in denosumab - treated patients . - pubmed
We excluded trials in cancer patients for prevention of skeletal - related events . - pubmed
Despite recently improved management of LSCC , chemotherapy resistance of patients remains a challenge . - pubmed
Of the plant - derived n-3 FAs , SDA showed the greatest inhibition of inflammation . - pubmed
All the prediction models were validated using 70 non - small cell lung cancer ( NSCLC ) patients treated with volumetric modulated arc therapy ( VMAT ) . - pubmed
Especially , from the results of the cellular morphology and proliferation of human cancer stem cells ( hCSCs ) cultured on the PEDOT nanofiber mats for 3 days , evidence was provided that the PEDOT nanofiber mats have similar biocompatibility to tissue culture plates ( TCPs ) . - pubmed
Successful Reduction of Intraocular Pressure in a Patient with Glaucoma Secondary to Sturge - Weber Syndrome Using a Suprachoroidal Shunt . - pubmed
Aim : We present a case of successful reduction of intraocular pressure ( IOP ) in a patient with Sturge - Weber syndrome ( SWS ) and moderate open angle glaucoma using a suprachoroidal shunt . - pubmed
Background : Patients with SWS glaucoma often have elevated episcleral venous pressure resulting in elevated IOP . - pubmed
Case description : We present a case where a suprachoroidal shunt device ( CyPass ) was used to reduce IOP in a patient with SWS . - pubmed
Clinical significance : Glaucoma in patients with SWS has been historically difficult to treat . - pubmed
Successful Reduction of Intraocular Pressure in a Patient with Glaucoma Secondary to Sturge - Weber Syndrome Using a Suprachoroidal Shunt . - pubmed
The present study included 23 relapsing - remitting MS ( RRMS ) patients , 23 seronegative NMOSD patients , and 23 healthy age - matched controls between 18 and 45 years of age . - pubmed
OBJECTIVE : This is the first investigation of the lipid - lowering and anti - atherosclerotic effects of Ganoderma lucidum spore ethanol extract ( EEG ) in hyperlipidemic rabbits . - pubmed
PATIENTS : Adults and children with retraction pocket cholesteatoma . - pubmed
Virulence and resistance determinants in Pseudomonas aeruginosa isolated from pericarditis in diseased broiler chickens in Egypt . - pubmed
Objective : This study was performed to probe the antimicrobial resistance and virulence genes profiling in Pseudomonas aeruginosa recovered from the cases of pericarditis in broiler chickens . - pubmed
Materials and methods : The samples ( n = 250 ) collected from the cases of pericarditis in broiler chickens were bacteriologically examined . - pubmed
aeruginosa recovered from pericarditis in broiler chickens in the present study with PAO1 ( reference strain ) and with other sequences published on the GenBank representing different localities worldwide . - pubmed
aeruginosa recovered from pericarditis in broiler chickens in the current study is highly virulent bacteria , resisting most of the therapeutic agents which not only bear hazards for poultry industry but also represent a public health concern . - pubmed
Most patients with multiple myeloma ( MM ) will eventually relapse and current treatments have limited effect . - pubmed
Their cytotoxic activities against human lung cancer cells A549 and human breast cancer cells MDA - MB-231 were evaluated using MTT method . - pubmed
All experimental broilers were injected intraperitoneally with 0.5 mg / kg body weight of either Escherichia coli LPS or sterile saline at 16 , 18 , and 20 d of age . - pubmed
We recruited 472 inpatients with chronic SCZ ( 54 T2DM and 418 non - T2DM ) , and 225 healthy controls . - pubmed
SCZ patients with T2DM scored higher in delayed memory than SCZ patients without T2DM ( 77.17 + - 18.44 vs.66.24 + - 19.51 , p = 0.000 ) , and still showed significance after controlling for confounders . - pubmed
Multivariate analyses ( after adjustment for other significant factors ) revealed that the changes in the abundance of Hungatella hathewayi in the gut were significantly associated with the development of eczema ( p = 0.005 ) . - pubmed
In conclusion , the increased abundance of Hungatella hathewayi was associated with an increased risk of developing eczema by 1 year of age . - pubmed
Terazosin and closely related drugs were recently discovered to enhance glycolysis and reduce PD progression in animal models and human clinical databases . - pubmed
Patients in the Danish cohort who used terazosin / doxazosin / alfuzosin had a hazard ratio ( HR ) for developing PD of 0.88 ( 95 % CI , 0.81 - 0.98 ) , and patients in the Truven cohort had an HR of 0.63 ( 95 % CI , 0.58 - 0.69 ) . - pubmed
Of the 179 patients diagnosed with a stroke mimic on TS , 27 ( 15 % ) were diagnosed with AIS / TA by discharge . - pubmed
We performed a preliminary assessment of SISPA - nanopore sequencing as a potential approach for screening tick - borne viruses in six specimens with detectable Crimean - Congo hemorrhagic fever virus ( CCHFV ) and Jingmen tick virus ( JMTV ) sequences . - pubmed
Isolation of a herpesvirus from the cell culture of a malignant melanoma of a ground squirrel ( Spermophilus tridecemlineatus ) . - pubmed
On the basis of the literature and of their own investigations , including animal experimentation , the authors attempt to show the possible causes of death following lightning strokes . - pubmed
Animal experiments give evidence of the important role of cardiac arrhythmias , in particular of asystolia and ventricular fibrillation . - pubmed
[ Pathogenesis of bone marrow necrosis in a patient with cancer ] . - pubmed
Bone marrow necrosis was observed in a 23 - year - old pregnant woman with severe anemia and thrombocytopenia due to bilateral ovarian carcinoma . - pubmed
Two boys ( two years and a half old ) were admitted in this hospital for an abdominal tumor . - pubmed
[ A hypophysis - abscess - syndrome in cattle . - pubmed
Two groups of subjects were studied : 24 healthy volunteers ( 19 right - handed ) , and 53 patients ( 42 right - handed ) with autosomal dominant FSHD . - pubmed
Intratracheal instillation of bleomycin in hamsters initiates a series of events that mimic human interstitial pulmonary fibrosis . - pubmed
The cases of nine patients who had a complex fracture of the distal part of the femur and a deficient medial - cortical buttress were reviewed . - pubmed
Additional stabilization with a medial plate and a bone graft from the iliac crest was applied in all nine patients : in six , at the time of the index operation and in the remaining three , after the open wound and open fracture were considered clean . - pubmed
Rat models showing similar facial defects have already been described . - pubmed
An asymmetric deformity was produced which was similar to that occasionally seen in man . - pubmed
Although conventional wisdom holds that pharmacological interventions improve the haemodynamic and clinical status of patients with chronic heart failure by enhancing systolic performance , this hypothesis fails to explain many of the responses seen following the administration of these drugs . - pubmed
This belief is supported by the following findings : ( 1 ) exercise capacity in chronic heart failure is more closely related to left ventricular filling pressure than to cardiac output or limb blood flow ; ( 2 ) only drugs that lower left ventricular filling pressure have been shown to improve exercise capacity , whereas drugs that primarily increase cardiac output or left ventricular ejection fraction do not enhance effort tolerance ; ( 3 ) the primary mechanism by which vasodilator and inotropic drugs lower left ventricular filling pressure is by exerting a favourable effect on left ventricular diastolic function rather than on left ventricular volume ; ( 4 ) drugs that improve diastolic function tend to affect favourably the clinical status of patients with chronic heart failure , whereas drugs that adversely alter ventricular relaxation produce deleterious haemodynamic and clinical effects . - pubmed
For our research , Bacillus pumilus spore strips and vaccinia virus were used as more heat - resistant surrogates of the human immunodeficiency virus ( HIV ) . - pubmed
pumilus has defined cell death values , whereas such values have not been established for HIV . - pubmed
The effects of negative regional lymph - node dissection on survival and disease - free interval of patients with stage - I malignant melanoma . - pubmed
A group of 46 patients , with stage-1 malignant melanoma of intermediate thickness and histologically proven negative regional lymph nodes , was retrospectively reviewed . - pubmed
A possible outbreak of listeriosis caused by an unusual strain of Listeria monocytogenes . - pubmed
During 1987 , a cluster of 23 cases of listeriosis due to an unusual serotype of Listeria monocytogenes was identified . - pubmed
Oral acyclovir reduces the incidence of recurrent herpes simplex keratitis in rabbits after penetrating keratoplasty . - pubmed
To determine if acyclovir sodium prevents postoperative herpes simplex virus type 1 ( HSV-1 ) recurrences , 21 rabbits harboring latent HSV-1 underwent uniocular autograft penetrating keratoplasty . - pubmed
In addition , 9 ( 82 % ) of 11 of the operated - on eyes had geographic ulcers develop in the non - acyclovir - treated rabbits , compared with 1 ( 10 % ) of 10 in the acyclovir - treated rabbits . - pubmed
Finally , stromal keratitis appeared in 5 ( 56 % ) of 9 of the operated - on eyes in non - acyclovir - treated rabbits and 1 ( 12 % ) of 8 of the operated - on eyes in acyclovir - treated rabbits . - pubmed
The results of this study indicate that acyclovir significantly lowered the incidence of HSV-1 ocular shedding , geographic ulceration , and stromal keratitis in a rabbit autograft penetrating keratoplasty model . - pubmed
To clarify the relationship between mitral regurgitation and left ventricular outflow obstruction , Doppler and two - dimensional echocardiographic studies were performed in 62 patients with hypertrophic cardiomyopathy ( 22 with and 40 without obstruction caused by mitral systolic anterior motion with septal contact ) . - pubmed
Pulsed Doppler echocardiography with color Doppler flow imaging demostrated that in 20 of the 22 patients with obstruction , mitral regurgitation occurred mainly during midsystole from the onset to the end of mitral - septal contact . - pubmed
A new modification in western blotting technique now permits the analysis of micro samples of blood collected from inhabitants of malaria endemic areas using several different antigens of Plasmodium falciparum . - pubmed
It seems to open new prospects for seroepidemiological studies of human malaria and for the selection of antigenic fractions that may allow the preparation of a vaccine . - pubmed
We studied the changes in heart rate evoked during the Valsalva maneuver in 49 asymptomatic Chagasic patients with different degrees of myocardial involvement . - pubmed
The Chagasic patients were divided in three groups . - pubmed
Sixteen patients had a normal electrocardiogram but revealed evidence of localized myocardial damage as shown by left ventricular cineangiography . - pubmed
These results are in discordance with the commonly accepted hypothesis that cardiac parasympathetic denervation causes a dilated myocardiopathy in patients with chronic Chagasic myocarditis . - pubmed
[ Laryngeal papillomatosis in children ] . - pubmed
In vitro growth of A431 human epidermoid carcinoma . - pubmed
An examination of 80 patients with ischaemic cerebrovascular disease , subdivided into 5 groups according to platelet antiaggregant treatment , demonstrated the insufficient effectiveness of acetylsalicylic acid in preventing recurrences . - pubmed
In view of the fact that all our patients showed radiologically detectable skeletal lesions of the head and neck , despite absence of symptoms in 35 per cent , it is advisable that all patients with von Recklinghausen ' s disease should routinely have radiological screening of this region , to detect early lesions . - pubmed
A 3 - year - old boy with segmental stenosis of the distal trachea and a 2 - year - old girl with segmental stenosis involving the carina and the right main bronchus were treated successfully with resection and reanastomosis . - pubmed
Prevention of cecitis in hamsters by certain prostaglandins . - pubmed
Acute inflammation of the colon ( cecitis ) was produced in hamsters by daily subcutaneous administration of an antibiotic for 3 days . - pubmed
Castor oil also prevented the cecitis and peanut oil exerted partial protection . - pubmed
A straight - line relationship observed in the death curve indicated a single target for aflatoxin B1 action in B. - pubmed
The involvement of plasma free fatty acids in ( + ) - amphetamine - induced hyperthermia in rats . - pubmed
Virilization superimposed on Turner ' s syndrome : cytogenetic studies of a gonadal tumor in a patient with XO - XY mixed gonadal dysgenesis . - pubmed
An indirect E - rosette augmentation ( ERA ) assay was used to study cellular reactivity and tumour - related serum reactions in mice bearing methylcholanthrene ( MCA)-induced tumours . - pubmed
The organism , designated strain 163 K , was isolated on modified Hayflick medium under aerobic conditions at 25 degrees C from the gills of a tench ( Tinca tinca L. ) . - pubmed
Study in Brattleboro rats with hereditary hypothalamic diabetes insipidus . - pubmed
In all patients bleeding stopped . - pubmed
The nonspecific host defense system of 66 patients with thermal injuries was studied prospectively . - pubmed
Prognosis of sexual maturation in prepubertal boys with micropenis . - pubmed
Long - term observations were made of the prognosis for sexual maturation ( onset of puberty ) in 15 prepubertal boys with micropenis . - pubmed
Blood coagulation and fibrinolysis in fertile women with previous thromboembolic complications and effects of venous occlusion . - pubmed
It is also a useful staging procedure in selected patients with pulmonary and esophageal tumors . - pubmed
We investigated the role of signal transduction systems in the attachment of human uveal melanoma cells to matrix proteins . - pubmed
Echocardiographic prediction of the final event in patients dying of acute myocardial infarction . - pubmed
From an autopsy series of 346 patients who died of acute myocardial infarction , we selected 36 cases for whom echocardiographic data preceding death were available : 17 cases died from a rupture of the left ventricular free wall ( group A ) and 19 from pump failure ( group B ) . - pubmed
The results of treatment in twenty - seven patients who had a Ewing sarcoma of the pelvis were reviewed . - pubmed
The actuarial over - all five - year survival was 45 per cent ( 23 to 65 per cent ) for all patients who had had localized disease when first seen . - pubmed
Radiofrequency catheter ablation in pediatric patients with supraventricular arrhythmias . - pubmed
A 38 year - old man presented fever and a clinical picture of intracranial hypertension and ataxic syndrome . - pubmed
By 14 days after injury , however , intimal area and SMC number were the same control and inhibitor - treated rats . - pubmed
An increased rate of SMC replication in the GM 6001 rats ( replication rates at 10 days were 56.7 + /- 10.0 % in the GM 6001 group and 16.97 + /- 1.73 % in the control group ) contributed to " catch - up " growth of the neointima . - pubmed
Because the ductus arteriosus bridges the two vascular circuits in this lesion , we studied the Doppler echocardiographic flow patterns in the ductus arteriosus of 50 infants with hypoplastic left heart syndrome to investigate their relationship to the degree of pulmonary blood flow as measured by simultaneously obtained levels of partial pressure of oxygen in arterial blood . - pubmed
Dysfunction in gastric myoelectric and motor activity in Helicobacter pylori positive gastritis patients with non - ulcer dyspesia . - pubmed
In Hp positive patients before the triple therapy the mean fasted antral diameter was 4.3 cm2 , initial EGG showed significant dysrhythmia of electrical control activity ( ECA ) with tachygastria up to 25 % of recording time in 9 of 12 Hp positive patients without normal increase of the power of signal in any of tested subjects . - pubmed
We conclude that most symptomatic non ulcer dyspeptic Hp positive patients show changes in ECA and antral hypomotility that are associated with Hp infections . - pubmed
Nondetectable cone and rod electroretinographic responses in a patient with Cockayne syndrome . - pubmed
A total of 123 strains of S hyodysenteriae and S innocens were correctly identified by the colony blot assay whereas all the 26 non - Serpulina Gram - negative organisms commonly isolated from faecal material or tissues of pigs remained negative . - pubmed
DESIGN : Twenty - one adult female mongrel dogs underwent either an open cholecystectomy , a laparoscopic cholecystectomy alone , or a laparoscopic cholecystectomy with peritoneal injury ( n = 7 for each group ) . - pubmed
Gastric dysrhythmias were observed in 23.8 % and 45.0 % of the dogs on postoperative days 1 and 2 , respectively . - pubmed
Adenovirus vector - mediated gene transfer into human epileptogenic brain slices : prospects for gene therapy in epilepsy . - pubmed
As a first step in the development of a gene therapy approach to epilepsy , we evaluated the ability of adenovirus vectors to direct the transfer into and expression of a marker gene in human brain slices obtained from patients undergoing surgery for medically intractable epilepsy . - pubmed
Similarly , results of irritability test demonstrated highest irritant behaviour of An . - pubmed
Maturation of the Tract After Percutaneous Cholecystostomy with Regard to the Access Route Purpose : To assess the shortest time for catheter removal with regard to the transhepatic or transperitoneal approach in patients undergoing percutaneous cholecystostomy ( PC).Methods : In this prospective study , 40 consecutive high - risk patients with acute cholecystitis ( calculous , n = 22 ; acalculous , n = 18 ) underwent PC by means of a transhepatic ( n = 20 ) or transperitoneal ( n = 20 ) access route . - pubmed
The electrocochleographic recordings were carried out in 61 patients with a clinical diagnosis of Meniere ' s disease and in 15 ears of normal hearing subjects . - pubmed
Cytotoxicity levels in human tumor cell lines were at comparable levels for several compounds . - pubmed
The effect of Cd2 + was similar , but acidosis had less effect than in rat myocytes ( e.g. - pubmed
The data indicate that acidosis and divalent cations influence Ito via a similar mechanism and act competitively in both rat and human myocytes , but that human cells are less sensitive to the effects of acidosis . - pubmed
PATIENTS AND METHODS : Ten eyes of eight patients with chronic open angle glaucoma who had undergone erbium - YAG laser sclerostomy ab externo were examined using a UBM - probe with a 20 MHz transducer providing spatial resolution of approximately 80 microm . - pubmed
Comparison of genetic susceptibility to experimental allergic / immune - mediated blepharoconjunctivitis between Lewis and Fischer rats . - pubmed
RESULTS : Fischer rats developed mild EAC compared with Lewis rats . - pubmed
CONCLUSION : EAC in Fischer rats was milder than that in Lewis rats , although no apparent differences in immunological parameters between these two strains were detected . - pubmed
By using the patient 's own cells , the procedure should obviate the need for immunosuppression and overcome the problem of tissue supply , while avoiding a recurrence of cell destruction . - pubmed
Importance of preoperative and postoperative pH monitoring in patients with esophageal achalasia . - pubmed
We report the case of a patient with synchronous MPC of the lung , with small cell carcinoma as the principal tumor associated with epidermoid carcinoma . - pubmed
These data could suggest that the addition of a single new agent to a platinum compound could be insufficient to substantially improve the prognosis of advanced NSCLC patients . - pubmed
In view of these disappointing data , the Southern Italy Cooperative Oncology Group has tried to improve the fate of patients with advanced NSCLC by testing new triplet combinations , which combined cisplatin with two rather than one of the newest chemotherapy agents . - pubmed
Evaluating the effectiveness of progressive muscle relaxation in reducing the aggressive behaviors of mentally handicapped patients . - pubmed
This article reports the results of a study on the evaluation of the effectiveness of muscle relaxation training in reducing aggressive behavior in mentally handicapped patients ( MHPs ) . - pubmed
Although the syndrome of inappropriate anti - diuretic hormone secretion has been recognised as a complication associated with burn and other trauma in adults , relatively little is known about its incidence in children . - pubmed
The objective of this study was to investigate whether it is a complication associated with burn injury in children . - pubmed
Recently , Mn was found to accumulate in brains of cirrhotic patients who also present motor abnormalities . - pubmed
The relationship of Mn content and DA turnover ( HVA : DA ) in the same animal showed a positive and statically significant correlation ( P<0.05 ) , with differences in slope for sham ( b1=0.1528 ) and cirrhotic rats ( b1=0.0174 ) . - pubmed
These results suggest that manganese brain accumulation observed in liver failure could be a key element to understand dopamine metabolism in cirrhotic condition of humans . - pubmed
Treatment of attention deficit hyperactivity disorder in children . - pubmed
These are controversial times for those who care for children with attention deficit hyperactivity disorder ( ADHD ) . - pubmed
Isolation and identification of pathogenic strains of Streptomyces acidiscabies from netted scab lesions of potato tubers in Hokkaido ( Japan ) . - pubmed
A relatively homogeneous group of streptomycete isolates was obtained from netted scab lesions of potato tubers collected from a potato field in Hokkaido , Japan . - pubmed
Based on 55 phenotypic data of 72 Streptomyces strains selected from these isolated together with spectral data on their soluble pigments and with data of a PCR analysis , using species specific primers , these netted scab causing pathogenic organisms were identified as S. - pubmed
[ Correlation of endotracheal tube biofilm and recurrent ventilator - associated pneumonia with Pseudomonas aeruginosa ] . - pubmed
In the present review , the authors summarize experiences with covered stents , and focus attention on available data on the implantation of PTFE - covered stents in human beings to treat coronary ruptures , aneurysms and aortocoronary vein graft stenosis . - pubmed
Circulating T - lymphocyte activation in patients with variant angina . - pubmed
DESIGN : To elucidate the role of systemic immune and inflammatory responses in the pathogenesis of coronary spasm , we studied circulating T - lymphocyte activation in variant angina patients ( VAPs ) , stable effort angina patients ( EAPs ) and in control participants . - pubmed
METHODS : Twenty documented VAPs , 13 EAPs and 20 control participants were studied . - pubmed
Treatment - induced anaemia and its potential clinical impact in patients receiving sequential high dose chemotherapy for metastatic testicular cancer . - pubmed
First - line sequential high dose chemotherapy is under investigation in patients with " poor prognosis " metastatic germ cell tumours in order to improve survival . - pubmed
This study investigates the frequency and degree of anaemia in patients receiving first - line sequential high dose chemotherapy for metastatic testicular cancer and the impact of anaemia on treatment outcome . - pubmed
A total of 101 newly diagnosed patients with " poor prognosis " metastatic nonseminomatous germ cell tumours were treated with one cycle of standard VIP followed by three cycles of HD - VIP - chemotherapy ( etoposide , ifosfamide , cisplatin ) within a large phase I / II study . - pubmed
Severe anaemia is a very frequent side effect of sequential dose intensive therapy in patients with germ cell cancer , with almost all patients becoming transfusion dependent . - pubmed
We performed a detailed retrospective clinicopathologic analysis of 43 patients who underwent LT for PBC . - pubmed
Patients with no recurrent disease had shorter follow - up periods and more frequent immunosuppression , including AZA ; some may still develop recurrence with longer follow - up . - pubmed
Surviving spleen graft rejected the lymphoma cells , but not in rats rejected the graft . - pubmed
Alefacept therapy produces remission for patients with chronic plaque psoriasis . - pubmed
In a previously published randomized , placebo - controlled phase II study of intravenous alefacept in 229 patients with chronic plaque psoriasis , clinical improvement was observed during dosing as well as in the postdosing follow - up period . - pubmed
Of 48 patients , 30 had suspected precancerous or cancerous laryngeal lesions , 7 presented benign laryngeal lesions , while 8 showed pharyngeal and 3 oral tumors . - pubmed
METHODS : The sera from 65 patients with colorectal cancer ( 18 at Dukes ' B , 24 at Dukes ' C , 23 at Dukes ' D ) were extracted before treatment . - pubmed
The aim of this study was to investigate the metabolic correlates of these deficits in a group of non - selected consecutive patients with frontal lobe lesions . - pubmed
PATIENTS AND METHODS : Clinicometabolic correlations between several emotional and social parameters and metabolic patterns in the frontal cortex and amygdala were investigated in 32 patients with frontal lobe pathologies . - pubmed
Pain - spot densities in human skin ; an experimental study . - pubmed
Recovery after anaphylaxis of isolated guinea pig ileum segments . - pubmed
The aim of this study was to determine the effects of improvements in urinary incontinence resulting from pelvic floor rehabilitation on the sexual function of patients . - pubmed
To evaluate whether changes in surgical technique have influenced this pattern of recurrence , a multicenter retrospective analysis was carried out on a patient population treated recently . - pubmed
Cloning of the mouse obesity gene in 1994 is perhaps the most famous impetus for recognition that adipocytes are active in the regulation of multiple body functions . - pubmed
Fetus - in - fetu ( FIF ) is a rare congenital condition in which a vertebrate fetus is incorporated within its twin . - pubmed
Epidemiology and risk factors of transmissible spongiform encephalopathies in man . - pubmed
Currently 60 % of patients with primary hyperparathyroidism can benefit of these techniques . - pubmed
In Part 2 , relevant data on the development of intestinal adaptation in studies involving humans will be reviewed as will the general management of SBS . - pubmed
METHODS : The patients were retrospectively divided into two groups ( hypolordotic and hyperlordotic ) using the lumbar lordosis on lateral lumbosacral view . - pubmed
DESIGN AND METHODS : We analyzed 1180 consecutive patients with leukemia ( n=979 ) or other hematologic malignancies ( n=201 ) undergoing HSCT in 4 time periods : before 1990 , 1991 - 1995 , 1996 - 2000 , and 2001 - 2002 . - pubmed
This is a consequence of reductions in GvHD , infections and multiorgan failure among patients in remission but not among those who relapse . - pubmed
There has been no improvement in survival for patients beyond first remission , due to persisting high risk of infections and organ toxicity , a possible consequence of prolonged pre - transplant chemotherapy and neutropenia . - pubmed
kleinii the pentacyclic triterpene alpha - amyrin , all caused a dose - related inhibition of both ear oedema ( ID50 values are 0.55 and 0.31 mg / ear , respectively ) and influx of polymorphonuclear cells ( ID50 values are 0.72 and 0.45 mg / ear , respectively ) in response to topical application of 12 - O - tetradecanoylphorbol - acetate ( TPA ) in the of mice ear . - pubmed
In a rat model , warm ischemia of the left lateral liver lobe was induced for 90 minutes under intraperitoneal anesthesia with xylazine and ketamine . - pubmed
We tested the hypothesis that small airway reticular basement membrane thickening exists even in clinically stable lung transplant recipients with some evidence of inflammation but who are BOS - free . - pubmed
Ursolic acid inhibits neointima formation in the rat carotid artery injury model . - pubmed
Administration of ursolic acid in the rat carotid balloon catheter injury model shows a significant inhibition of neointimal hyperplasia . - pubmed
In vitro activity of tigecycline against isolates from patients enrolled in phase 3 clinical trials of treatment for complicated skin and skin - structure infections and complicated intra - abdominal infections . - pubmed
Tobacco use and stomach cancer in Mizoram , India . - pubmed
Tuibur ( tobacco smoke - infused water ) , used mainly in Mizoram , was seemed to increased the risk of stomach cancer among current users in both univariate and multivariate models ( OR , 2.1 ; 95 % CI , 1.3 - 3.1 ) . - pubmed
Tobacco use in any form [ smoking and smokeless ( tuibur and chewing ) ] increased the risk of stomach cancer in Mizoram independently after adjusting for confounding variables . - pubmed
Because acute hemolysis is caused by exposure to an oxidative stressor in the form of an infection , oxidative drug , or fava beans , treatment is geared toward avoidance of these and other stressors . - pubmed
Furthermore , in a trial conducted in patients with corticosteroid - induced osteoporosis , intermittent i.v . - pubmed
These simple ibandronate regimens are expected to provide the optimal combination of efficacy , tolerability and patient convenience , leading to improved treatment adherence and thus , enhanced outcomes in postmenopausal osteoporosis . - pubmed
Immune cell apoptosis may play a role in human persistent Helicobacter pylori infection . - pubmed
PATIENTS : Forty - eight patients ( 34 females and 14 males ) with a histologically confirmed diagnosis of appendiceal carcinoid were included in the study . - pubmed
Appendiceal carcinoid was diagnosed incidentally in all 48 patients . - pubmed
Following review of the literature , we were unable to find any recent evidence of distant metastasis from carcinoids in patients already treated by appendectomy . - pubmed
Fatty acids of rice coleoptiles in air and anoxia . - pubmed
However , there is still much unknown regarding the nature and concentration of RCOs in HD patients . - pubmed
This study was designed to evaluate the level of toxic aldehydes in the plasma of HD patients and to determine the extent to which these aldehydes contribute to RCO toxicity among these patients . - pubmed
METHODS : 15 aldehydes of the alkanal , alkenal and 4 - HO - alkenal type were measured in the plasma of 17 HD patients and 20 healthy controls . - pubmed
CONCLUSION : The increased levels of alkanals , alkenals and 4 - HO - alkenals of lipid peroxidation in the plasma of HD patients may greatly contribute to the toxicity of RCOs . - pubmed
Scarless skin repair in immunodeficient mice . - pubmed
Scarring , the end result of the wound healing process in adult mammals , is a problem of significant clinical importance . - pubmed
We observed that athymic nude - nu mice , similar to mammalian fetuses , are able to restore the structure and integrity of injured skin through a process resembling regeneration , where scar formation is absent . - pubmed
CONCLUSION : Term infants with a low Apgar score have cochlear impairment , mainly at the frequencies 1 - 3 kHz . - pubmed
OBJECTIVE : To detect any peripheral impairment of cochlear origin in infants with a low Apgar score . - pubmed
SUBJECTS AND METHODS : Fifty - four term infants with a low Apgar score at 1 and/or 5 min but without clinical signs of hypoxic - ischaemic encephalopathy were recruited . - pubmed
MATERIAL AND METHODS : A summary is given from recently published meta - analyses on three possible clinical applications of human papillomavirus ( HPV)-DNA testing : triage of women with equivocal or low - grade cytological abnormalities ; prediction of the therapeutic outcome after treatment of cervical intraepithelial neoplasia ( CIN ) lesions , and last not but not least , primary screening for cervical cancer and pre - cancer . - pubmed
After treatment of cervical lesions , HPV testing easily detects ( with higher sensitivity and not lower specificity ) residual or recurrent CIN than follow - up cytology . - pubmed
CONCLUSIONS : Sufficient evidence exists to recommend HPV testing in triage of women with atypical cytology and in surveillance after treatment of CIN lesions . - pubmed
Cognitive functions in patients with MR - defined chronic focal cerebellar lesions . - pubmed
The aim of the present study was to examine cognitive functions in a group of chronic patients with focal cerebellar lesions . - pubmed
Fourteen patients with infarctions within the territory of the posterior inferior cerebellar artery ( PICA ) and seven patients with infarctions within the territory of the superior cerebellar artery ( SCA ) participated . - pubmed
The right cerebellar hemisphere was affected in eight PICA and two SCA patients , the left hemisphere in six PICA and four SCA patients . - pubmed
One SCA patient revealed a bilateral lesion . - pubmed
In sum , the results showed preserved cognitive abilities in chronic cerebellar patients apart from impairments of verbal fluency in patients with right - cerebellar lesions . - pubmed
The discovery of epigenetic silencing as a key mechanism of tumor suppressor gene inactivation in human cancer has led to great interest in utilizing epigenetic modulatory drugs as cancer therapeutics . - pubmed
Recent work has begun to dissect the specific epigenetic mechanisms controlling differential expression of CG antigen genes in human cancers . - pubmed
Taken together , these data encourage clinical evaluation of combination therapies involving epigenetic modulatory drugs and CG antigen - directed tumor vaccines for the treatment of human malignancies . - pubmed
OBJECT : The purpose of this study was to measure the dose of radiation delivered to the cochlea during a Gamma knife surgery ( GKS ) procedure for treatment of patients with vestibular schwannomas ( VSs ) , and to analyze the relationship between cochlear irradiation and the hearing outcome of these patients . - pubmed
METHODS : Eighty - two patients with VSs were treated with GKS using a marginal dose of 12 Gy . - pubmed
CASE PRESENTATION : A 70 - year - old male underwent low anterior resection with total mesorectal excision for a rectal adenocarcinoma . - pubmed
Atomoxetine increases histamine release and improves learning deficits in an animal model of attention - deficit hyperactivity disorder : the spontaneously hypertensive rat . - pubmed
To that end , the aim of our study was to investigate the effect of atomoxetine ( 2 mg / kg , intraperitoneally ) on histamine release using the microdialysis technique in the spontaneously hypertensive rat ( SHR ) , a suitable genetic model for ADHD . - pubmed
Chronic schizophrenic patients with a long - term disease process and medication period have not been investigated so far . - pubmed
Subsequently , AG014699 dose was fixed at PID and temozolomide escalated to maximum tolerated dose or 200 mg / m2 in metastatic melanoma patients whose tumors were biopsied . - pubmed
Improved prognosis of patients with primary biliary cirrhosis that have a biochemical response to ursodeoxycholic acid . - pubmed
BACKGROUND & amp ; AIMS : Ursodeoxycholic acid ( UDCA ) improves laboratory liver test results in patients with primary biliary cirrhosis ( PBC ) . - pubmed
We performed a prospective multicenter study of patients with PBC treated with UDCA to compare prognosis with biochemical response . - pubmed
CONCLUSIONS : Prognosis for UDCA - treated patients with early PBC is comparable to that of the general population . - pubmed
At the same time , human neural stem cells ( hNSC ) were transfected under different multiplicity of infection . - pubmed
These mice show myometrial hyperplasia and develop mesenchymal tumors with 100 % penetrance that exhibit histological and molecular characteristics of human leiomyomas and endometrial stromal sarcomas . - pubmed
Additionally , adenomyosis and endometrial gland hyperplasia were occasionally observed in some mice . - pubmed
Testing for the reappearance of lesions after injection of the patient 's own erythrocytes is usually useful for the diagnosis of AES , but the significance of this test is still controversial . - pubmed
We report a 28 - year - old woman who presented recurrent episodes of painful purpura with vertigo and hemilateral auditory impairment after difficulties at her workplace . - pubmed
These findings suggest that treatment for psychological disorders is important in patients with AES . - pubmed
METHODS : From Jan 2005 to Dec 2006 , 31 selected patients ( 22 males and 9 females , aged from 41 to 63 years ) with degenerative lumbar diseases were treated with minimally invasive TLIF assisted by METRx X - Tube micro - endoscopy system . - pubmed
METHODS : Three patient groups totalling 28 subjects with diabetes [ group A 10 Type 1 ( Ulm ) , group B 10 Type 1 ( Neuss ) , group C eight Type 2 ( Aarhus ) ] participated in this trial . - pubmed
The average absolute differences were 1.14 mmol / l for Type 1 and 0.88 mmol / l for Type 2 diabetic patients . - pubmed
Relative absolute differences were 16.0 % for Type 1 and 12.6 % for Type 2 diabetic patients . - pubmed
CONCLUSIONS : These results demonstrate that this microdialysis system allows reliable continuous glucose monitoring in patients with diabetes of either type . - pubmed
PURPOSE : To evaluate a low vision rehabilitation service implemented for heterogeneously diverse group of Egyptianpatients with vision loss in terms of improving their visual performance and fulfilling their visual needs . - pubmed
METHODS : Fifty patients with low vision were included in a prospective study . - pubmed
OBJECTIVE : The purpose of this study was to evaluate contrast - enhanced ultrasound and neural network data classification for determining the breast cancer response to bevacizumab therapy in a murine model . - pubmed
Twenty - five nude athymic mice with orthotopic breast cancers received a 30 - microL tail vein bolus of a perflutren microsphere UCA , and baseline tumor imaging was performed using microbubble destruction - replenishment techniques . - pubmed
RESULTS : The breast cancer response to a single dose of bevacizumab in a murine model was immediate and transient . - pubmed
DESIGN AND METHODS : Sixty - nine untreated adults with T - cell acute lymphoblastic leukemia were evaluated by oligonucleotide arrays : unsupervised and supervised analyses were performed . - pubmed
Of these , one branch included seven patients whose gene expression profile resembled that of acute myeloid leukemia . - pubmed
Using one functional single- nucleotide polymorphism ( SNP ; rs6295 ) and one tagging SNP ( rs878567 ) , we conducted a genetic association analysis of case - control samples ( 857 schizophrenic patients , 1028 BP patients and 1810 controls ) in the Japanese population . - pubmed
Here , we investigated whether alterations in endocannabinoid ( eCB ) signaling in the NAc contribute to depression - like behaviors induced by chronic unpredictable stress ( CUS ) in mice . - pubmed
[ Preventive relapse treatment for tobacco cessation - is it worthwhile ? ] - pubmed
We herein provide a selected overview of tobacco relapse prevention strategies evaluated in different trials and in a recent meta - analysis . - pubmed
Currently there is insufficient evidence to recommend systematic preventive relapse treatment for tobacco addiction with psychological or pharmacological interventions . - pubmed
Extended treatment with Varenicline may reduce relapse rates following tobacco cessation . - pubmed
Further meticulously designed and appropriately powered trials will be necessary to clarify the role of alternative psychological and pharmacological strategies for the prevention of relapse after tobacco cessation . - pubmed
Moreover , VB-201 , an orally available synthetic phospholipid analog of the Lecinoxoid family , was found to attenuate inflammation in various preclinical animal models and is currently employed in a phase II clinical trial in psoriasis . - pubmed
We present the first evidence for the uptake of nodularin by a terrestrial plant , and show that the exposure of spinach to cyanobacterial crude water extract from nodularin - producing strain AV1 results in inhibition of growth and bleaching of the leaves . - pubmed
Treatment of mice with Sphingomab resulted in blood B and T cell lymphopenia . - pubmed
No benefit of a proximal stem centralizer in cementing of a femoral prosthesis in human cadavers . - pubmed
A total of 136 faecal samples from buffalo ( n = 122 ) and cow calves ( n = 14 ) exhibiting clinical signs of diarrhoea and from healthy calves were collected during 2007 - 2010 from subtropical ( central India ) and tarai area of western temperate Himalayan foothills ( Uttarakhand ) . - pubmed
Among the five PBV samples identified , three were from buffalo calves and one from cow calf exhibiting clinical signs of acute diarrhoea , while one sample from non - diarrhoeic buffalo calf also showed the presence of PBV . - pubmed
None of the samples showed dual infection of rotavirus and PBV . - pubmed
The preliminary findings indicate sporadic incidences of PBV in bovine calves and emphasize the need for the development of better diagnostics for early detection and genetic characterization of these emerging isolates of farm animals of economic significance . - pubmed
Previously , we demonstrated that reproductive senescence was associated with mitochondrial deficits comparable to those of female triple - transgenic Alzheimer 's mice ( 3xTgAD ) . - pubmed
Depletion of ovarian hormones by ovariectomy ( OVX ) in nontransgenic mice significantly decreased brain bioenergetics , and induced mitochondrial dysfunction and oxidative stress . - pubmed
These findings provide a plausible mechanism for increased risk of Alzheimer ' s disease in premenopausally oophorectomized women while also suggesting a therapeutic strategy for prevention . - pubmed
We report a case involving a 34 - year - old woman who presented with a persistent skin rash over her neck and upper body , with clinical features suggestive of dermatomyositis . - pubmed
Hematologic changes after total body irradiation and autologous transplantation of hematopoietic peripheral blood progenitor cells in dogs with lymphoma . - pubmed
Dogs with and without lymphoma have undergone hematopoietic cell transplantation in a research setting for decades . - pubmed
All dogs had & gt;= 500 neutrophils / mul by day 12 , while thrombocytopenia persisted for many weeks . - pubmed
502 patients will be recruited and randomized into two arms : patients in arm A will receive IMRT in 28 fractions delivering 50.4 Gy to the breast and 64.4 Gy to the tumor bed by integrated boost , while patients in arm B will receive conventional radiotherapy of the breast in 28 fractions to a dose of 50.4 Gy and consecutive boost in 8 fractions to a total dose of 66.4 Gy . - pubmed
Epidemiological data indicate that low serum vitamin D concentrations are associated with an increased risk of a variety of human tumours . - pubmed
Cutaneous mast cell tumours ( MCT ) occur more frequently in dogs than in any other species . - pubmed
To examine this association , serum 25 - hydroxyvitamin D3 ( 25 ( OH ) D3 ) concentrations were examined in eighty - seven Labrador retrievers , including thirty - three with MCT and fifty - four unaffected controls . - pubmed
OBJECTIVES : We describe the clinical presentation of a 7 1/2 - year - old boy with a history of mild intermittent asthma who presented with left lung collapse and was found to have plastic bronchitis . - pubmed
METHODS : We reviewed the patient chart and imaging results and performed a literature review of plastic bronchitis and its management . - pubmed
MATERIAL AND METHOD : Between 2009 and 2010 , 90 cases with MG , treated at the adult neurology service of King Chulalongkorn Memorial Hospital were consecutively recruited . - pubmed
Graft / patient status was classified as stable , serious infection , or malignancy . - pubmed
IFT levels were analyzed with duration of follow - up after OLT , graft / patient status , and the presence of hepatitis C ( HCV ) infection . - pubmed
Clinically stable patients had higher IFT levels than those with serious infection or malignancy ( 254 + -11.1 vs. 162.5 + -23.9 , p<0.001 ) . - pubmed
Fresh vegetables , fruit and fish provide protection from OSCC . - pubmed
Management of patients with OPMD and treated OSCC include careful life - long follow - up . - pubmed
This international , randomized , placebo - controlled , double - blinded phase III trial examines the efficacy and safety of ramucirumab treatment administered in combination with docetaxel , as compared with docetaxel administered with placebo , in patients with stage IV non - small - cell lung cancer ( NSCLC ) whose disease progressed during or after first - line platinum - based chemotherapy with or without maintenance treatment . - pubmed
Both drugs are administered via intravenous infusion once every 3 weeks until evidence of disease progression , unacceptable toxicity , noncompliance , or patient 's consent withdrawal . - pubmed
Efficacy and safety will be compared between the study arms and in patient subgroups including patients with nonsquamous versus squamous tumor histology and patients who received prior bevacizumab treatment . - pubmed
The goal of the REVEL study is to demonstrate that ramucirumab in combination with docetaxel improves overall survival of patients with NSCLC with progressive disease after first - line therapy , and to advance our knowledge of the role of angiogenesis blockade in patients with NSCLC by identifying patients who are likely to experience maximum benefit based on extensive clinical biomarker correlative analysis . - pubmed
[ Nonpharmacological methods of prevention of thromboembolic complications in patients with atrial fibrillation ] . - pubmed
We present in this review modern methods of prevention of thromboembolic complications in patients with atrial fibrillation and give comparative description of evidence base , efficacy and safety of available techniques . - pubmed
We describe 4 patients with respiratory diseases where C. - pubmed
Chronic , sometimes fatal infections by the ascomycete Aspergillus fumigatus and the basidiomycete Schizophyllum commune are well established in the presence of an anatomical pulmonary defect or in the background of immunodeficiency . - pubmed
Early rehabilitation in patients operated for breast carcinoma . - pubmed
Its expression in the chrysanthemum was up - regulated by salinity or dehydration stress , but not by abscisic acid ( ABA ) . - pubmed
There was also limited evidence that prophylactic antibiotics reduced bacteriuria in non - surgical patients . - pubmed
Interplay between autophagy and apoptosis mediated by copper oxide nanoparticles in human breast cancer cells MCF7 . - pubmed
These CuO NPs ( ~30 nm ) induce autophagy in human breast cancer cell line , MCF7 in a time- and dose - dependent manner . - pubmed
Irrespectively of the many possible mechanisms of HBV reactivation in patients infected with HIV ( escape mutants selection , host immune deficiency progression , antiretroviral - related immune reconstitution , glucocorticosteroids , chemotherapy ) , the message is that HIV patients should be monitored strictly not only by serological and virological assays to recognize early HBV reactivation , but also for drug over - exposure . - pubmed
METHOD : A total of 99 consecutive adult patients ( & gt;= 18 years ) with diagnosis of somatoform disorders according to the International Classification of Diseases-10th Revision ( ICD-10 ) were evaluated for their explanatory models using the causal models section of Explanatory Model Interview Catalogue ( EMIC ) . - pubmed
METHODS : Consecutive patients with ICH were enrolled as part of the Multicenter Study on Cerebral Hemorrhage in Italy ( MUCH - Italy ) . - pubmed
Within the subgroup of patients taking OACs , international normalized ratio ( INR ) values were higher in those with lobar ICH as compared to those with deep ICH ( 2.8 + - 1.1 vs 2.2 + - 0.8 ; p = 0.011 ) . - pubmed
The proportion of patients with lobar hematoma increased with increasing intensity of anticoagulation , with a ~2 - fold increased odds of lobar compared to deep ICH ( odds 2.17 ; p = 0.03 ) in those exposed to overanticoagulation ( INR values & gt;3.0 ) . - pubmed
The purposes of this study were to describe the effects of B1AA on survival in septic animals and to explore for molecular mechanisms of potential treatment benefit . - pubmed
Immunologic disease ( p = 0.0003 - 0.036 ) and cell death / survival ( p = 0.0001 - 0.042 ) were significantly associated with improved survival in septic mice treated with B1AA . - pubmed
RESULTS : 80 patients with 339 thyroid nodules were included . - pubmed
Ten thyroid cancers ( TCs ) in ten patients were diagnosed in histopathology . - pubmed
Therefore , in this study , in order to understand the role of cell cycle regulators in preeclamptic placentas we aimed to determine the spatio - temporal immunolocalizations of cell cycle regulators in preeclamptic and normal human term placentas . - pubmed
In this study , we evaluated the incidence , clinical features , risk factors , and outcomes of ES in children and adults undergoing first - time allogeneic HCT . - pubmed
Among 927 patients , 119 ( 13 % ) developed ES at a median of 10 days ( interquartile range 9 to 12 ) after HCT . - pubmed
ES patients experienced significantly higher cumulative incidence of grade 2 to 4 acute GVHD at day 100 ( 75 % versus 34 % , P & lt ; .001 ) and higher nonrelapse mortality at 2 years ( 38 % versus 19 % , P & lt ; .001 ) compared with non - ES patients , resulting in lower overall survival at 2 years ( 38 % versus 54 % , P & lt ; .001 ) . - pubmed
Despite early recognition of the syndrome and prompt institution of corticosteroid therapy , outcomes in ES patients were uniformly poor . - pubmed
METHODS : Male Japanese subjects with or without AGA ( n = 369 ) were included in this study . - pubmed
We also showed that Pkd1 ( RC / RC ) mice experience hepatic hypertrophy that can be corrected by pasireotide . - pubmed
Effects of AFO use on walking in boys with Duchenne muscular dystrophy : a pilot study . - pubmed
The aim of this pilot study was to describe the effects of dynamic response AFO ( DR - AFO ) use in boys with DMD who are ambulatory . - pubmed
OBJECTIVE : To identify patient factors and health care utilization patterns associated with dose escalation during the first year of long - term opioid therapy for chronic pain . - pubmed
MATERIAL AND METHODS : From September 2007 to August 2012 , 55 patients with large rectal carcinoid tumors were treated by EMR - C ( 30 cases ) or ESD ( 25 cases ) . - pubmed
Twenty four hours following reperfusion of a 2 - h ischemic stroke , rats received either 0.56 - mg / kg DETC - MeSO or 40 - mg / kg of taurine , either alone or in combination , subcutaneously for 4days . - pubmed
MATERIALS AND METHODS : Twenty - one patients suffering from irregularly formed tracheostoma after laryngectomy followed by insertion of a speech valve were provided with a silicone tracheostomal prosthesis . - pubmed
Going green : using a bio - cellulose membrane for patients with chronic non - healing wounds . - pubmed
METHODS : Three patients underwent laparoscopic abdominal wall reconstruction for complex hernias in August and September of 2015 . - pubmed
CONCLUSION : Laparoscopic abdominal wall reconstruction with transversus abdominis release is a unique and feasible approach to complex abdominal wall defects with the potential to reduce pain , facilitate recovery , and decrease length of hospital stay for patients . - pubmed
RESULTS Patients complained of CLBP for 11.32 + -6.81 years on average . - pubmed
Comparative Effects of Roux - en - Y Gastric Bypass and Sleeve Gastrectomy on Glucose Homeostasis and Incretin Hormones in Obese Type 2 Diabetic Patients : A One - Year Prospective Study . - pubmed
The aim of the work was to compare the hormonal and the metabolic mechanisms involved in weight loss and remission of T2DM one year after Roux - en - Y gastric bypass ( RYGB ) and vertical sleeve gastrectomy ( VSG ) in morbidly obese type 2 diabetic ( T2DM ) patients . - pubmed
BACKGROUND : Increased free cortisol fraction is associated with insulin dysregulation ( ID ) in people with Metabolic Syndrome and Cushing ' s Disease . - pubmed
Free cortisol has not been investigated in equine endocrine disorders . - pubmed
ANIMALS : Fifty - seven healthy horses ; 40 horses and ponies with PPID ( n = 20 ) or EMS ( n = 20 ) . - pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : Increased FCF is associated with obesity in healthy horses and with ID ( hyperinsulinemia ) in horses and ponies with endocrine disease . - pubmed
Decreased plasma cortisol - binding capacity could be a component of these endocrine disorders in horses . - pubmed
One trial , with 84 participants , treated mild sensory impairment of less than six months ' duration , and the other , with 95 participants , treated nerve function impairment of 6 to 24 months ' duration . - pubmed
No systemic infection with visible symptoms or accumulation of viral DNA in the upper leaves was observed in H24 challenged with another isolate , TYLCV - IL ( TYLCV - IL [ JR : Osaka ] ) , confirming that H24 is resistant to the IL strain . - pubmed
We report 2 cases of hypothyroidism in whom the associated haematological disturbances ( macrocytic anaemia in both cases , mild leukopenia and thrombo - penia in one patient ) failed to be corrected by thyroid hormone replacement therapy . - pubmed
These findings in humans were consistent with the results from a pilocarpine - induced animal model of chronic epilepsy . - pubmed
Indoor tobacco legislation is associated with fewer emergency department visits for asthma exacerbation in children . - pubmed
Switching to aflibercept among patients with treatment - resistant neovascular age - related macular degeneration : a systematic review with meta - analysis . - pubmed
PURPOSE : To systematically review anatomical and functional outcomes subsequent to switching from bevacizumab / ranibizumab to aflibercept monotherapy in patients with treatment - resistant neovascular age - related macular degeneration ( nAMD ) . - pubmed
These patients had poorly responsive chronic disease with limited potential for visual recovery . - pubmed
The European Association for Neuro - Oncology guideline provides recommendations for the clinical care of adult patients with astrocytic and oligodendroglial gliomas , including glioblastomas . - pubmed
The recommendations are a resource for professionals involved in the management of patients with glioma , for patients and caregivers , and for health - care providers in Europe . - pubmed
The aim of this study was to evaluate the prevalence of parasitological contamination ( helminthes eggs , Giardia and Entamoeba histolytica cysts ) of salad vegetables sold at supermarkets and street vendors in Amman and Baqa'a - Jordan . - pubmed
cysts was 23 % , 6 % , 0 % and 0 % ; Taenia / Echinococcus eggs was 20 % , 0 % , 5 % and 0 % ; Fasciola hepatica eggs was 13 % , 3 % , 2 % and 0 % ; and E. - pubmed
Neuroprotective effects of vitamin D alone or in combination with lamotrigine against lithium - pilocarpine model of status epilepticus in rats . - pubmed
Therefore , in the present study , the neuroprotective effects and mechanisms of vit - D alone or in combination with lamotrigine have been evaluated in the lithium - pilocarpine model of SE in rats . - pubmed
A strain of Vibrio parahaemolyticus that emerged in 1995 caused the first known pandemic involving this species . - pubmed
Chemopreventive effect of artesunate in 1,2 - dimethylhydrazine - induced rat colon carcinogenesis . - pubmed
Diabetes Mellitus in Children . - pubmed
BACKGROUND : Patients with kidney dysfunction are at risk of developing ischaemic heart disease . - pubmed
CONCLUSIONS : We report a strong association between kidney function and all - cause mortality at both early , mid- and long - term follow - up in patients undergoing coronary angiography and intervention , with eGFR significantly associated with MI - related mortality after one month of follow - up . - pubmed
Further research is warranted to explore the mechanisms linking kidney function and cardiovascular disease to improve both the short- and long - term care of these patients . - pubmed
Methods : A mouse xenograft model of spontaneous tumor metastasis was used to determine the metabolic rewiring that occurs between primary cancers and their metastases . - pubmed
Metabolite analysis of normal lung tissue in the mouse model also revealed increased levels of these metabolites compared to tissues from normal MFP and primary MFP tumors , indicating potential extracellular uptake by cancer cells in lung metastases . - pubmed
BACKGROUND : The adoption of novel and effective gastric cancer therapies into general clinical practice has crucial implications for patient outcomes . - pubmed
The current study explored trends in treatment use and overall survival in patients with gastric cancer in the United States . - pubmed
METHODS : Patients with adenocarcinoma of the gastric cardia and noncardia were identified in the National Cancer Data Base between 2006 and 2014 . - pubmed
RESULTS : A total of 89,098 patients with gastric adenocarcinoma were identified . - pubmed
In those with early - stage cancer , endoscopic treatment increased over time in patients with cardia and noncardia disease . - pubmed
In patients with locally advanced cardia disease , preoperative therapy use increased over time ( 2013 - 2014 [ vs 2006 - 2008 ] : odds ratio [ OR ] , 3.09 ; 95 % confidence interval [ 95 % CI ] , 2.80 - 3.41 ) . - pubmed
In patients with locally advanced noncardia disease , the use of preoperative therapy also increased ( 2013 - 2014 : OR , 3.32 ; 95 % CI , 2.88 - 3.82 ) as did the use of perioperative therapy ( 2013 - 2014 : OR , 4.21 ; 95 % CI , 3.52 - 5.03 ) in lieu of postoperative treatment ( 2013 - 2014 : OR , 0.66 ; 95 % CI , 0.60 - 0.71 ) . - pubmed
In patients with metastatic disease , approximately 34 % of patients with cardia and 40 % of patients with noncardia cancer did not receive treatment . - pubmed
CONCLUSIONS : Practice patterns for the treatment of gastric cancer in the United States reflect the increased adoption of evidence - based therapies , including endoscopic resection of early - stage cancer and preoperative therapy for patients with locally advanced disease . - pubmed
In this system , a gelatin sponge soaked with tumor cells , cell - conditioned medium , or a compound to be tested is implanted , for 2 - 4 weeks , between the two mouse ear skin layers . - pubmed
Experimental Design : We produced 14 orthoxenograft transplanting human nonseminomatous testicular germ cell tumors ( TGCT ) in mice , keeping the primary tumor features in terms of genotype , phenotype , and sensitivity to cisplatin . - pubmed
RT - PCRs in tumors and functional analyses in Caenorhabditis elegans ( C. - pubmed
The virus had been discovered in 2015 as the cause of a cluster of cases of fatal encephalitis among breeders of variegated squirrels ( Sciurus variegatoides ) in eastern Germany . - pubmed
Phylogenetic analyses demonstrated a spillover infection from the Prevost ' s squirrel . - pubmed
Drug - induced abnormal heart rhythm known as Torsades de Pointes ( TdP ) is a potential lethal ventricular tachycardia found in many patients . - pubmed
Here , we present a single patient who underwent bilateral microelectrode - guided stereotactic implantation of deep brain stimulating leads for the treatment of essential tremor 52 yr following bilateral arm amputations . - pubmed
NEW & amp ; NOTEWORTHY We had a unique opportunity to record neurons in the ventrointermediate ( Vim ) motor nucleus of thalamus in a patient with essential tremor , decades following bilateral forearm amputations . - pubmed
METHODS : For Phase 1 , we will create a master list of HIV and STI testing sites in each city . - pubmed
Although severe blood coagulopathy in horses with acute colitis causes multiple organ failure , which may be fatal , few studies have focused on the correlation between the fluctuations of coagulation parameters and severity of colitis . - pubmed
In this study , we evaluated the fluctuations of coagulation parameters in 14 Thoroughbred racehorses with acute colitis for 5 days from the day of hospitalization and compared them between 5 survivors and 9 non - survivors . - pubmed
PURPOSE : To identify women affected by recurrent ovarian cancer who benefit from secondary cytoreductive surgery ( SCS ) , analyse their clinical and biological features and investigate the role of minimally invasive surgery ( MIS ) and hyperthermic intraperitoneal - based chemotherapy ( HIPEC ) in this subset of patients . - pubmed
CONCLUSIONS : While waiting for the final results of the ongoing randomized controlled trials , SCS seems feasible and safe in selected patients with recurrent ovarian cancer . - pubmed
All 7 studies found an increased odds for at least 1 extracutaneous infection , including endocarditis , meningitis , encephalitis , bone and joint infections , and sepsis , in AD patients . - pubmed
CONCLUSION : AD patients have higher odds of extracutaneous infections . - pubmed
One patient was treated conservatively with an external fixator but died the next day , 2 patients received a new total hip arthroplasty and 47 underwent plate fixation of their fracture ( one patient was treated non - operatively because of poor medical condition ) . - pubmed
The type of pathological response to neoadjuvant chemoradiation in patients with locally advanced esophageal cancer predicts overall survival ( OS).We aimed to assess early 18F - FDG positron emission tomography / computed tomography parameters in predicting the pathological response to neoadjuvant treatment . - pubmed
The cohort included consecutive patients with locally advanced esophageal cancer who underwent baseline 18F - FDG positron emission tomography / computed tomography between September 2006 and February 2015 . - pubmed
MTV at presentation is associated with the pathological response to neoadjuvant chemoradiation in patients with locally advanced esophageal cancer . - pubmed
BACKGROUND : Hepatitis C virus ( HCV ) point - of - care testing using rapid diagnostic test ( RDT ) is the solution for large - scale , feasible , fast and reliable screening of HCV infection . - pubmed
OBJECTIVES : The aim of this study was to evaluate the diagnostic performance of HCV RDT for screening of HCV infection in a real - life prison setting . - pubmed
However , with exclusion of testing error in prison and considering HCV RNA as the reference method for diagnosis of current HCV infection the sensitivity reached 100 % . - pubmed
METHODS : People living with HIV ( PLHIV ) initiating antiretroviral therapy at 22 HIV clinics were enrolled and underwent systematic screening for TB ( August 2012 - November 2014 ) . - pubmed
RESULTS : Among 6041 patients enrolled ( smear arm , 1816 ; Xpert arm , 4225 ) , 256 ( 199 per 2985 and 57 per 1582 person - years of follow - up in Xpert and smear arms , respectively ; adjusted incidence rate ratio , 9.07 ; 95 % confidence interval [ CI ] : 4.70 - 17.48 ; p & lt ; 0.001 ) received TB diagnosis and were treated . - pubmed
Effects and cost - effectiveness of postoperative oral analgesics for additional postoperative pain relief in children and adolescents undergoing dental treatment : Health technology assessment including a systematic review . - pubmed
BACKGROUND : There is an uncertainty regarding how to optimally prevent and/or reduce pain after dental treatment on children and adolescents . - pubmed
Fiber dissection and brain functional mapping in 90 patients with gliomas . - pubmed
Second , 90 patients underwent awake craniotomy for gliomas with direct electrical stimulations . - pubmed
The body weight , body composition , food intake , and energy expenditures of the mice were measured . - pubmed
In this report , we describe a 61 - year - old man with isolated sweating on the left side of his entire body . - pubmed
The pulmonary involvement in children with COVID-19 was mild with a focal GGO or consolidation . - pubmed
INTERPRETATION : Atypical clinical findings of pregnant women with COVID-19 could increase the difficulty in initial identification . - pubmed
Back From the Brink : Alterations in B and T Cell Responses Modulate Recovery of Rainbow Trout From Chronic Immunopathological Tetracapsuloides bryosalmonae Infection . - pubmed
Proliferative kidney disease ( PKD ) caused by the myxozoan parasite Tetracapsuloides bryosalmonae is one of the most serious infectious diseases negatively impacting farmed and wild salmonids throughout Europe and North America . - pubmed
The study also showed non - optimal treatment of patients with hypertension . - pubmed
The most statin administration was observed in hypertensive patients with coronary artery disease ( 50.1 % ) and myocardial infarction ( 62.7 % ) . - pubmed
Corneal Epithelial Findings in Patients with Multiple Myeloma Treated with Antibody - Drug Conjugate Belantamab Mafodotin in the Pivotal , Randomized , DREAMM-2 Study . - pubmed
INTRODUCTION : Patients with relapsed or refractory multiple myeloma ( RRMM ) represent an unmet clinical need . - pubmed
The first event resolved in most patients ( grade > = 2 MECs and visual acuity [ each 77 % ] , blurred vision [ 67 % ] , and dry eye [ 86 % ] ) , with no reports of permanent vision loss to date . - pubmed
CONCLUSION : Single - agent belamaf represents a new treatment option for patients with RRMM . - pubmed
OBJECTIVE : To explore the potential indicators including patients ' characteristics , electrocardiogram ( ECG ) , echocardiography , and serological assay in predicting the major adverse cardiovascular events ( MACE ) within 1 year for patients with low - risk chest pain with a nomogram . - pubmed
PATIENTS AND METHODS : The detected indicators of patients with low - risk chest pain were obtained as the alternative predictors for MACE . - pubmed
A nomogram was constructed based on the multivariable Cox regression to link the independent predictors and the MACE within 1 year for patients with low - risk chest pain . - pubmed
Rhythmic auditory stimulation ( RAS ) has been well researched with stroke survivors and individuals who have Parkinson ' s disease , but little research exists on RAS with people who have experienced traumatic brain injury ( TBI ) . - pubmed
Dual - energy X - ray absorptiometry can be useful to detect abnormal bone mass and fracture risk in this population and newer bone assessment methods are being evaluated in children at risk for poor bone outcomes . - pubmed
Metabolomic profiling of IgG4 - RD patients offers an opportunity to identify novel pathophysiological targets and biomarkers . - pubmed
CONCLUSION : IgG4 - RD patients have a unique plasma metabolomic profile compared with healthy controls . - pubmed
Bacillus subtilis Inhibits Viral Hemorrhagic Septicemia Virus Infection in Olive Flounder ( Paralichthys olivaceus ) Intestinal Epithelial Cells . - pubmed
Bacillus subtilis is a probiotic with excellent antiviral properties , of which one of its secretions , surfactin , has been shown to inhibit viral infections in mammals . - pubmed
Herein , we demonstrate its ability to prevent VHSV infection in olive flounder ( Paralichthys olivaceus ) intestinal epithelial cells ( IECs ) and infection in internal organs . - pubmed
Our findings show inhibition of VHSV infection in IECs by B. - pubmed
Mitochondrial degeneration after organic phosphate poisoning in prosimian primates . - pubmed
The degenerative reaction of mitochondria to tricresylphosphate ( TCP ) poisoning in spinal ganglion cells of Slow Loris ( Nycticebus coucang coucang ) were studied with the electron microscope . - pubmed
In neurones of animals treated with TCP , mitochondria display various stages of alterations which confirm mitochondrial involvement in TCP poisoning . - pubmed
Clinical , radiological and functional pulmonary manifestations in patients with leptospirosis . - pubmed
Separate groups of rats were sampled by decapitation every 3 or 4 hours in two separate studies during a 24 h period consisting of 12 h light and 12 h dark . - pubmed
The multidrug - resistant strains most commonly isolated were lactose - fermenting Citrobacter freundii . - pubmed
The overall resistance of these aquaria strains was greater than the previously described resistance of clinical isolates of C. - pubmed
Efficacy of training in obese diabetic patients . - pubmed
cells found in dogs and cats with neurologic disorders , such as reactive monocytes and lymphocytes , macrophages , neutrophils and eosinophils in addition to cells of the first group , 3 . - pubmed
Transient elevation of the intracranial pressure increases the infarct size and perifocal edema after subsequent middle cerebral artery occlusion in the rat . - pubmed
The objective of this study was to mimic in a simple experiment the two major brain insults sustained by the patient with a subarachnoid hemorrhage , that is , the ictus and the subsequent delayed reduction of focal cerebral blood flow caused by vasospasm without the interference of subarachnoid blood , to test the hypothesis that ictal events not related to the presence of blood in the subarachnoid space per se may be important for the development of ischemic deficits and cerebral infarction when vasospasm develops . - pubmed
Groups of rats were subjected to a sudden transient elevation of the intracranial pressure to a level causing a brief period of complete global ischemia by infusion of mock cerebrospinal fluid into the cisterna magna ( this manipulation was designed to allow survival of the animal and recovery of consciousness ) . - pubmed
Rats subjected to middle cerebral artery occlusion alone and sham operation served as controls . - pubmed
Functional digital subtraction sialography with a water soluble radiopaque agent ( verografin ) made it possible to investigate the structure and functional changes in the salivary glands of 26 patients with a minimum injury of the glands . - pubmed
A number of natural and synthetic sugar analogues have been tested for their antiviral activity , using an influenza virus strain as a model . - pubmed
Changes that occur in mice with experimentally induced cryptorchidism are not identical to those seen in the rat . - pubmed
Teaching patients with ventricular dysrhythmias . - pubmed
The infarct size , estimated by % Defect decreased significantly in the patients treated with V , while it remained unchanged in the patients without it . - pubmed
In the patients with V , the left ventricular ejection fraction was more favourable , and exercise - induced ischemia determined by redistribution of 201 - Tl SPECT in the chronic phase was found more frequently . - pubmed
Guar additives did not improve the excessive postprandial glycemia found in NIDDM patients in whom near - normal fasting plasma glucose levels had been obtained . - pubmed
It was previously determined that surgery plus the antibiotic doxycycline were effective in eliminating or suppressing Actinobacillus actinomycetemcomitans ( Aa ) , an organism strongly associated with disease in localized juvenile periodontitis ( LJP ) . - pubmed
Eight patients with LJP participated in this surgical study . - pubmed
STUDY OBJECTIVE : To determine the prevalence of vertebral fractures in patients with mild asymptomatic primary hyperparathyroidism and to ascertain whether this prevalence is increased in comparison with the rate in a retrospective control group previously studied at the same institution or with current estimates of the risk for vertebral fractures in subjects of similar age . - pubmed
PATIENTS : A consecutive series of patients with mild asymptomatic primary hyperparathyroidism diagnosed between 1 January 1976 and 31 December 1985 . - pubmed
MEASUREMENTS AND MAIN RESULTS : The prevalence of vertebral fractures in 174 patients ( mean age , 62 years ) with mild asymptomatic primary hyperparathyroidism was 1.7 % ; in a subset of white women , the prevalence was 2.8 % . - pubmed
CONCLUSIONS : The risk for vertebral fractures is not increased in patients with mild asymptomatic primary hyperparathyroidism and is not a reason to recommend surgical intervention in asymptomatic patients . - pubmed
[ Antiparasitic activity of Cis - Pt ( II ) pentamidine in experimental trypanosomiasis of sheep caused by Trypanosoma brucei brucei ] . - pubmed
brucei brucei , Cis - Pt ( II ) pentamidine was evaluated on an experimental sheep trypanosomiasis model , standardized by the Institute of Neurological Epidemiology and Tropical Neurology of Limoges ( France ) . - pubmed
Cis - Pt ( II ) pentamidine was able to cure infected mice , without relapse , after a single subcutaneous injection of 12.5 mg.kg-1 body weight . - pubmed
In sheep trypanosomiasis , the same treatment was used successfully during the first stage of infection . - pubmed
Rabies was confirmed in dogs that died by mouse inoculation and subsequent examination of mouse brains by fluorescent antibody technique to detect rabies antigen . - pubmed
To evaluate this test further , a dog was infected by rabies virus , and serial serum and CSF specimens were collected until the time of death . - pubmed
Clonazepam , a high - potency benzodiazepine marketed for the treatment of minor motor epilepsy , was used to treat 50 patients with panic disorder ( N = 22 ) or agoraphobia with panic attacks ( N = 28 ) . - pubmed
Staphylococcosis in a commercial rabbitry . - pubmed
[ The effect of 2 % calcium citrate on the incidence of caries in rats ] . - pubmed
Pathogenesis of osteopetrosis in chickens . - pubmed
Spontaneous disappearance of tumorigenicity in a polyoma virus - induced neoplasm carried in vitro . - pubmed
[ The mineral feeding in sheep herds with clinical cases of hypocalcemia ] . - pubmed
Five patients with ARN were seen . - pubmed
Biopsy of one lesion yielded herpes simplex virus ( HSV ) in culture . - pubmed
Twenty - five upper extremities were operated upon in 24 patients because of arterial occlusive disease . - pubmed
Characterization of the peptide and sensory neurotoxic effects of capsaicin in the guinea pig . - pubmed
The results indicate that in the guinea pig capsaicin is potent at producing a unique , long - lasting syndrome of peripheral sensory deficits that may result from an effect of the agent on SP - containing primary afferent neurons . - pubmed
Study of kinetics of epithelial cell populations in normal tissues of the rat 's intestines and in carcinogenesis . - pubmed
To compare the accuracy of 3DE with standard 2DE algorithms for quantitating LV volume , 28 excised canine ventricles of known volume and varying shapes ( 15 symmetric and 13 aneurysmal ) and 10 instrumented dogs prepared so that instantaneous ventricular volume could be measured were examined by 2DE ( bullet and biplane Simpson 's formulas ) and again by 3DE . - pubmed
Antiarrhythmic and electrophysiologic effects of ibutilide in a chronic canine model of atrial flutter . - pubmed
We studied the effects of orally administered ibutilide , a class III antiarrhythmic agent , in a model of reentrant atrial flutter in conscious dogs . - pubmed
After baseline determination of atrial effective refractory period ( AERP ) and demonstration of reproducible induction of atrial flutter by rapid atrial pacing , 8 dogs received either placebo or one of six doses of ibutilide ranging from 0.1 to 5 mg / kg . - pubmed
INTRODUCTION : The purpose of the study was to evaluate the effect of pregnancy and childbirth on the longterm prognosis for women with multiple sclerosis ( MS ) . - pubmed
METHOD AND MATERIAL : A cohort of 39 women with definite MS were identified on 1.1.1986 using a reproducible selection method . - pubmed
OBJECTIVE : To present the CT and MR findings of three patients with giant intracranial aneurysms ( GIAs ) , each of which eroded the skull base and had an extracranial mass component . - pubmed
MATERIALS AND METHODS : In the past year the imaging studies of three patients with these unusual GIAs were collected at our institutions . - pubmed
Polymyxin B and an antiserum against an Re mutant Salmonella typhimurium were evaluated for protective effect in an equine model endotoxemia . - pubmed
Reduced effect of inhaled beta 2 - adrenergic agonists on lung mucociliary clearance in patients with cystic fibrosis . - pubmed
Thus , we questioned whether the beta 2 - adrenergic agonist , terbutaline , would improve mucociliary clearance in patients with CF as it does in healthy subjects . - pubmed
PATIENTS : Ten young patients with CF were studied ; three were heterozygous for deletion of the phenylalanine at position 508 ( delta F508 ) , and seven were delta F508 homozygous . - pubmed
CONCLUSIONS : We conclude that 1 mg of terbutaline did not improve mucociliary clearance significantly in the patients with CF . - pubmed
Histopathologic and ultrastructural findings of photocoagulation lesions produced by transpupillary diode laser in the rabbit retina . - pubmed
81 patients were suffering from hematologic malignancies and severe aplastic anemia and six patients had advanced solid tumours / sarcoma . - pubmed
Probability of survival for patients transplanted in the first chronic phase of chronic myelogenous leukemia ( CML ) was 85 % , whereas the disease free survival ( DFS ) for patients transplanted in accelerated phase or blast crisis was only 40 % . - pubmed
All patients transplanted for non - Hodgkin ' s lymphoma ( NHL ) or Hodgkin ' s disease had refractory or advanced disease . - pubmed
Probability of survival for lymphoma patients was 60 % . - pubmed
Results were compared with 44 historical control patients treated with CY ( 120 mg / kg ) and TBI . - pubmed
RESULTS : The 3 - year actuarial disease - free survival ( DFS ) rate was similar for the BU / CY / TBI group and the CY / TBI group ( 23 % v 30 % , P = .6 ) , but there were trends toward lower relapse rates ( 28 % v 54 % , P = .27 ) and higher nonrelapse mortality rates ( 68 % v 36 % , P = .12 ) among the current patients compared with historical controls . - pubmed
CONCLUSION : Patients with advanced morphology myelodysplasia tolerated the intensified BU / CY / TBI preparative regimen and reduced posttransplant immunosuppression poorly . - pubmed
Predicting patient outcome in acute renal failure has become increasingly important as technology advances and ethical questions arise concerning life supporting therapies . - pubmed
STUDY SELECTION : English - language articles that discussed the role of medications in the treatment of human obesity , and studies that evaluated their safety and efficacy for a minimum of 24 weeks . - pubmed
Until more data are available , pharmacotherapy can not be recommended for routine use in obese individuals , although it may be helpful in carefully selected patients . - pubmed
[ Protein and RNA biosynthesis in the nuclei of the thymus cells of piglets with antenatal hypotrophy ] . - pubmed
Differential serological diagnosis of HTLV - I and HTLV - II infection by external membrane protein peptide - based enzyme immunoassays . - pubmed
BACKGROUND : HTLV antibody screening assays detect both antibodies to the etiological agent of adult T - cell leukemia and tropical spastic paraparesis HTLV - I and to the less pathogenic HTLV - II . - pubmed
The peptide EIA with the best performance was further used to differentiate between HTLV - I and HTLV - II antibodies in 807 samples from 18 countries in four continents and to provide ratios between the two infections . - pubmed
The sensitization phase of contact hypersensitivity induced by the hapten , dinitrofluorobenzene ( DNFB ) in the mouse was used as a model of T lymphocyte trafficking in response to antigenic stimulation . - pubmed
Cognitive performances are usually lower in patients with arterial hypertension . - pubmed
A longitudinal study revealed that patients with AD aged 79 - 85 are more likely to have had higher values of blood pressure 10 to 15 years earlier , and they usually have a spontaneous decline of blood pressure beginning 1 or 2 years before the onset of AD . - pubmed
[ Effects of chronic hypoxia on the expression of oncogene jun fos and myb mRNA in rat lung ] . - pubmed
This paper is to investigate the expression of oncogene jun fos and myb mRNA in the lung of rats exposed to chronic hypoxia . - pubmed
The results showed that ( 1 ) there was a slight expression of jun mRNA but not fos and myb mRNA in the control normoxic rats ' lung ; ( 2 ) it was found that a less expression of jun mRNA in lung after 1 week hypoxia , but after 2 week hypoxia jun mRNA elevated again and significantly increased after 3 week hypoxia as compared with that in normoxia ; ( 3 ) the oncogene myb mRNA expression showed significant increase in 1 and 2 week hypoxia and returned to normal status in 3 week hypoxia ; ( 4 ) after 1 to 3 week hypoxia , a significant increased expression of fos mRNA was found as compared with that in normoxia . - pubmed
RESULTS : The proportion of 12 - year - old children with no experience of dentine caries was 47 % and 35 % were completely free from all caries . - pubmed
While the outcome for patients with advanced non - small cell lung carcinoma is still poor , new agents are being developed rapidly and offer the hope of improved survival . - pubmed
The median concentration of dioxin in fathers in this study is similar to doses that induce epididymal impairments in rats and is about 20 times the estimated average concentration of TCDD currently found in human beings in industrialised countries . - pubmed
A-60 - year - old man with medically intractable left - sided maxillary division trigeminal neuralgia had severe cardiac disease , was dependent on an internal defibrillator and could not undergo magnetic resonance imaging . - pubmed
The patient was pain free 2 months after GKS . - pubmed
Foam cell lesions were the only type of lesion in 12 of the aortas from transgenic animals , while five animals had developed fibrofatty lesions . - pubmed
Neutrophilic eccrine hidradenitis unassociated with chemotherapy in a patient with acute myelogenous leukemia . - pubmed
SAMPLE POPULATION : Twenty limbs ( 10 limb pairs ) from 5 equine cadavers . - pubmed
In general , HIV transmission in host - migrant or host - forced - migrant interactions depends on the maturity of the HIV epidemic in both the host and the migrant population , the relative seroprevalence of HIV in the host and the migrant population , the prevalence of other sexually transmitted infections ( STIs ) that may facilitate transmission , and the level of sexual interaction between the two communities . - pubmed
In complex emergencies , additional factors such as sexual interaction between forced - migrant populations and the military ; sexual violence ; increasing commercial sex work ; psychological trauma ; and disruption of preventive and curative health services may increase the risk for HIV transmission . - pubmed
Atypical antipsychotics have revolutionized the treatment of schizophrenia , becoming the treatment of choice for patients not only during their first episode , but also throughout their life course . - pubmed
Atypical agents may be particularly helpful for elderly , child , or adolescent patients who are especially susceptible to the side effects of medications and whose risk of tardive dyskinesia is high but further controlled studies are necessary . - pubmed
Intravenous / oral sequential therapy in patients hospitalised with community - acquired pneumonia : which patients , when and what agents ? - pubmed
A new trend in antibacterial therapy is sequential therapy ( intravenous / oral ) in hospitalised patients with moderate to severe infections . - pubmed
CAP requires prompt and effective antibacterial treatment and conventional therapy for patients hospitalised with CAP has typically been parenteral antibacterial therapy for 7 to 10 days . - pubmed
Today a large number of clinical trials in patients with CAP have been undertaken and sequential therapy with appropriate antibacterials used in suitable patients has been proven as a treatment option . - pubmed
In the studies presented here we provide data on our lead preclinical compound and compare its antivascular and antitumour activity to that of CA4P in the murine breast adenocarcinoma CaNT . - pubmed
pylori eradication can be considered one of the methods to prevent gastric cancer in patients with H. - pubmed
22 - kHz ultrasonic vocalization in rats as an index of anxiety but not fear : behavioral and pharmacological modulation of affective state . - pubmed
Ultrasonic vocalization ( USV ) was found useful for differentiating fear and anxiety in rats . - pubmed
METHODS : Seventeen hydrogel lenses were explanted from 17 different patients owing to decreased visual acuity or quality of vision an average of 29 months after uneventful phacoemulsification and IOL implantation and associated with a granular - appearing opacification superficially within the optic . - pubmed
[ CLINICO - BIOCHEMICAL COMPARATIVE STUDIES IN THE DIAGNOSIS OF EARLY PHASES OF DEVELOPMENT OF HEPATIC DYSTROPHY IN PATIENTS WITH BOTKIN ' S HEPATITIS ] . - pubmed
vivax infections , one in buffalo and another in a cow , PCR detected infections in 34.8 % buffaloes , 44.7 % bovines and 37.3 % sheep . - pubmed
Trypanozoon primers detected 41.8 % infections in buffaloes and 8.1 % in cattle . - pubmed
PCR revealed 6.9 % mixed infections in buffaloes and 5.3 % in cattle . - pubmed
Both patients were treated by clipping of the aneurysm , and the signs of oculomotor nerve paresis gradually resolved . - pubmed
A pattern of pupil - sparing paresis was observed during the early recovery stage in both patients . - pubmed
We propose that CSF analysis may become part of the diagnostic work - up of patients with parkinsonian syndromes . - pubmed
Some old mice fight parasitic infection better than young mice do . - pubmed
METHODS : Thirty - seven patients with short bowel syndrome received bowel rehabilitation therapy for 4 weeks . - pubmed
Thirty - four patients were treated within 2 years after short bowel syndrome . - pubmed
RESULTS : All patients completed the treatment ; there were no deaths caused by malnutrition . - pubmed
vivax / Plasmodium malariae mixed infection ( 3.0 % ) . - pubmed
In conclusion , increases in malaria cases , mostly due to P. - pubmed
In an in vitro analysis of 41 individual patient - derived primary tumor samples , B - cell chronic lymphocytic leukemia ( B - CLL ) and marginal zone lymphoma showed the strongest activation upon stimulation with CpG oligodeoxynucleotides . - pubmed
Focusing clinical studies on patients with highly CpG oligodeoxynucleotide - sensitive B - cell malignancies may improve the clinical outcome of such trials . - pubmed
Advances in allergic skin disease , anaphylaxis , and hypersensitivity reactions to foods , drugs , and insects . - pubmed
This review highlights some of the research advances in allergic skin disease , anaphylaxis , and hypersensitivity reactions to foods , drugs , and insects that were reported primarily in the Journal in 2004 . - pubmed
Polioencephalomalacia in cattle in New Zealand fed chou moellier ( Brassica oleracea ) . - pubmed
Polioencephalomalacia was diagnosed clinically in 26 heifers from a herd of 99 grazing chou moellier ( Brassica oleracea ) . - pubmed
A positive patient history or family history of allergy were documented . - pubmed
In this study we determined whether a similar change takes place in patients with bipolar disorder with and without a history of psychosis . - pubmed
BACKGROUND : Left atrium ( LA ) in patients with hypertrophic cardiomyopathy ( HC ) has been known to have an increased size and decreased contractile function . - pubmed
METHODS : We performed real - time 3D echocardiography on 26 patients with HC and on 15 control subjects . - pubmed
Patients with HC showed decreased LV early diastolic dV / dt compared with control subjects ( 0.10 + /- 0.05 vs 0.14 + /- 0.04 mL / ms , P & lt ; .05 ) . - pubmed
In rats and mice , the middle cerebral artery occlusion ( MCAO ) model was used to represent cerebrovascular stroke , while in gerbils the two - vessel occlusion model , representing global ischemia , was used . - pubmed
In the second half of this review , we present data on neuroprotection by estrogen and progesterone in animal model of epilepsy followed by exploration into ovarian steroid effects on neuronal damage in models of multiple sclerosis and traumatic brain injury . - pubmed
Ongoing studies are being performed to determine if the addition of panitumumab to first - line standard treatment for metastatic colorectal cancer will improve the progression - free and overall survival of these patients . - pubmed
This study examined seasonal changes in body weight , hibernation period , and body temperature of the Japanese badger ( Meles meles anakuma ) from 1997 to 2001 . - pubmed
A-56 - yr - old Malay man was diagnosed to have adenocarcinoma of the right colon [ Dukes B ] for which a right hemicolectomy was performed , followed by radiotherapy and chemotherapy . - pubmed
Animal studies demonstrated that females are more susceptible than males to benzo [ a ] pyrene ( BaP)-induced toxicities , including lung carcinogenesis . - pubmed
METHODS : A total of 356 patients with confirmed diagnosis of active RA from 9 clinical centers were randomly assigned to the TCM group ( 184 cases ) and the WM group ( 172 cases ) . - pubmed
RESULTS : The platelet count was positively correlated to the X- ray grading of joint damage , namely , patients with a more severe joint damage often presented a higher platelet count . - pubmed
CONCLUSION : Platelet count is closely correlated to the efficacy of drug therapy , therefore , it may be taken as an important index for judging the curative effect of therapeutic approach in treating RA patients . - pubmed
Experimental diabetes treated with Achillea santolina : effect on pancreatic oxidative parameters . - pubmed
In the present study , we examined possible protective effect of Achillea santolina L. ( Compositae ) against pancreatic damage in streptozotocin ( STZ)-treated diabetic rats . - pubmed
ASE ( 0.1g / kgday ) was orally administered to a group of diabetic rats for 30 consecutive days . - pubmed
A 38 - year - old woman presented after 2 weeks with penetrating craniocerebral injury from a six inch nail . - pubmed
AN UPDATE ON CAT SCRATCH DISEASE : Cat scratch disease is an uncommon and infectious disease of man characterized by regional lymphadenopathy following a scratch or a bite from a cat or other inoculation wounds . - pubmed
Preoperative three - dimensional computed tomographic scans were used to acquire the stereolithographic biomodeling of the patient for assessing the amount of bone defect and precise planning of the surgery . - pubmed
It shows bactericidal activity against forms of Staphylococcus aureus ( phagolysosomal infection ) with different resistance phenotypes [ methicillin - resistant S. - pubmed
We assessed the status of dopamine nerve terminals in patients treated with dopamine receptor blocking agents ( DRBAs ) who had developed drug - induced parkinsonism ( DIP ) . - pubmed
We performed [ ( 123 ) I ] FP - CIT SPET in 32 consecutive patients who were on DRBAs for at least 6 months and developed extrapyramidal signs . - pubmed
Conversely , symmetry of parkinsonian signs and presence bucco - linguo - masticatory dyskinesias were more frequent in individuals with normal tracer binding . - pubmed
Lutzomyia longipalpis ( Diptera , Psychodidae , Phlebotominae ) and urbanization of visceral leishmaniasis in Brazil . - pubmed
The article discusses habits related to the vectorial competence of Lutzomyia longipalpis , along with evidence confirming the importance of this sand fly species in the epidemiological chain of visceral leishmaniasis in Brazil . - pubmed
A new epidemiological profile for visceral leishmaniasis is also postulated , associated with domestic environments and the role of Lu . - pubmed
METHODS : We asked whether the correlation previously established in rodents extends to the best nonhuman primate model of PD , the 1 - methyl-4 - phenyl-1,2,3,6 - tetrahydropyridine ( MPTP)-lesioned macaque . - pubmed
Inter - rater reliability of three standardized functional tests in patients with low back pain . - pubmed
BACKGROUND : Of all patients with low back pain , 85 % are diagnosed as " non - specific lumbar pain " . - pubmed
The aim of this present study was to therefore standardize and examine the inter - rater reliability of three functional tests of muscular functional coordination of the lumbar spine in patients with low back pain . - pubmed
A 67 - year - old man with celiac disease developed recurrent diarrhea , profound weakness and weight loss , with evidence of marked protein depletion . - pubmed
[ Genomic damage , adaptive response induction in blood lymphocytes at the prostate cancer patients . - pubmed
It was shown that in oncological patients the DSB level and the frequency of cells with MN have been increased . - pubmed
We can suppose that prognosis of the treatment efficiency of the prostate cancer patients with the pronounced adaptive response in blood lymphocytes will be worse . - pubmed
We aimed to investigate whether PCI had different clinical outcomes from ACI in Chinese patients with ischemic stroke . - pubmed
METHODS : Data on ischemic stroke patients with ACI or PCI were collected including demographics , risk factors and 1 - month , 3 - month , and 1 - year case fatality and disability ( defined as modified Rankin Scale 3 - 5 ) . - pubmed
The adjusted hazard ratio of death for PCI was 0.52 at 1 month ( 95 % CI 0.29 - 0.94 ) and 0.52 at 3 months ( 95 % CI 0.31 - 0.85 ) , and the adjusted odds of disability in patients with PCI was 0.53 at 1 year ( 95 % CI 0.35 - 0.81 ) . - pubmed
Knowledge on the biodistribution and potential shedding of AAV2 is crucial to evaluate the risks of infection with the viral vector for the patient and the environment . - pubmed
Individual patient data from four randomised trials in fibromyalgia ( 2575 patients ) lasting 8 - 14weeks were used to calculate percentage pain reduction for each completing patient ( 1858 ) , divided into one of five groups according to pain reduction , irrespective of treatment : substantial benefit - 50 % pain reduction ; moderate - 30 % to & lt;50 % ; minimal - 15 % to & lt;30 % ; marginal - 0 % to & lt;15 % ; worse - & lt;0 % ( increased pain intensity ) . - pubmed
Infection with Chlamydia pneumoniae ( Cp ) accounts for around 10 % of community acquired bacterial pneumonia and has been associated with other chronic inflammatory conditions . - pubmed
We describe a C57 / Bl6 murine model of Cp lung infection characterized by a dose - dependent , resolving neutrophilia followed by lymphocytic infiltration of the lungs . - pubmed
DENTAL caries in the rhesus monkey . - pubmed
This study reports on the molecular systems biology of gastrointestinal nematode ( GIN ) infection and potential biomarkers for GIN resistance in sheep . - pubmed
These results provide specific gene targets for therapeutic interventions and provide insights into GIN infections in sheep which may be used to infer the same in related host species . - pubmed
Endotracheal nebulization of N - acetylcysteine increases airway resistance in cats with experimental asthma . - pubmed
We hypothesized that in cats with experimental asthma , aerosol delivery of NAC ( 400 mg cumulative dose ) via an endotracheal tube would increase airflow limitation as measured by ventilator - acquired mechanics . - pubmed
After endotracheal drug delivery , airway resistance and inspiratory plateau pressure ( Pplat ) measurements were obtained in six mechanically ventilated asthmatic cats . - pubmed
All cats exhibited at least one adverse effect : excessive airway secretions ( n=3 ) , spontaneous cough ( n=2 ) , unilateral strabismus ( n=1 ) and post - anesthetic death ( n=1 ) . - pubmed
No adverse reactions were noted with saline aerosol ; cough was noted in one cat with methacholine challenge . - pubmed
Further studies must be performed to evaluate if it is an effective mucolytic and/or antioxidant in cats and to determine if bronchodilator pre - treatment will negate NAC - induced bronchoconstriction . - pubmed
End - stage renal disease : sudden cardiac death : stratifying risk in dialysis patients . - pubmed
Furthermore , variability in enterocyte injury was observed among hyphal - producing C. - pubmed
A mouse model of term chorioamnionitis : unraveling causes of adverse neurological outcomes . - pubmed
A mouse model of intrauterine inflammation at term was utilized by injecting lipopolysaccharide ( LPS ) , or normal saline into uterine horn . - pubmed
THE PURPOSE OF THE RESEARCH : This study was designed to assess knowledge and attitude with respect to epilepsy among secondary school students ( epileptic and none ) in Assiut city , Egypt . - pubmed
Only 7.1 % of epileptic students and 8.5 % of non - epileptic students thought that the epilepsy is a brain disease . - pubmed
MATERIAL AND METHOD : The authors reviewed the data of dose measurement record from 53 patients ' treatment files to report the uniformity of absorbed in vivo dose distribution throughout the whole body from TBI with semiconductor detectors and ionization chamber with the accepted homogeneity within + /- 10 % of the prescribed dose . - pubmed
In - vitro studies demonstrated that 2 and 4 were active against HeLa ( human cervical cancer ) , A375 ( human malignant melanoma ) , HepG2 ( human hepatocellular carcinoma ) , MCF-7 ( human breast cancer ) , A549 ( human nonsmall cell lung cancer ) , K562 ( human chronic myeloid leukemia ) , and K562 / ADR ( human adriamycin - resistant K562 ) cell lines with IC(50 ) values in the range of 3.2 - 64.1 muM. - pubmed
Vibrio parahaemolyticus is a marine bacterium , responsible for gastroenteritis in humans . - pubmed
Atypical strains of V. - pubmed
Surgical intervention in vascular trauma in children . - pubmed
Arterial injury in children presents a challenge to the surgeon and may have long - term implications . - pubmed
METHODS : Patients ( & lt;13 years ) with vascular injury requiring surgical intervention were retrospectively reviewed from a trauma database of 446 trauma patients admitted to the Tygerberg Children 's Hospital . - pubmed
RESULTS : We reviewed a total of 20 children where surgical intervention for vascular trauma was required . - pubmed
The first Plasmodium vivax relapses of life are usually genetically homologous . - pubmed
Distinctive features between community - acquired pneumonia ( CAP ) due to Chlamydophila psittaci and CAP due to Legionella pneumophila admitted to the intensive care unit ( ICU ) . - pubmed
The spectrum of community - acquired pneumonia ( CAP ) due to Chlamydophila psittaci ranges from mild , self - limited CAP , to acute respiratory failure . - pubmed
We performed a retrospective study of 13 consecutive patients with CAP due to C. - pubmed
Human erythrocytes and neuroblastoma cells are in vitro affected by sodium orthovanadate . - pubmed
This report presents evidence in order that orthovanadate interacted with red cell membranes as follows : a ) in scanning electron microscopy ( SEM ) studies it was observed that morphological changes on human erythrocytes were induced ; b ) fluorescence spectroscopy experiments in isolated unsealed human erythrocyte membranes ( IUM ) showed that an increase in the molecular dynamics and/or water content at the shallow depth of the lipids glycerol backbone at concentrations as low as 50muM was produced ; c ) X - ray diffraction studies showed that orthovanadate 0.25 - 1mM range induced increasing structural perturbation to DMPE ; d ) somewhat similar effects were observed by differential scanning calorimetry ( DSC ) with the exception of the fact that DMPC pretransition was shown to be affected ; and e ) fluorescence spectroscopy experiments performed in DMPC large unilamellar vesicles ( LUV ) showed that at very low concentrations induced changes in DPH fluorescence anisotropy at 18 C. Additional experiments were performed in mice cholinergic neuroblastoma SN56 cells ; a statistically significant decrease of cell viability was observed on orthovanadate in low or moderate concentrations . - pubmed
Recent discovery of Taxol a diterpenoid obtained form Taxus species has opened new vistas in the treatment of cancer and can be considered a major break through . - pubmed
Patients with intense carbon black exposure following industrial accidents will need frequent evaluation to manage any related respiratory tract injury . - pubmed
Imipramine protects mouse hippocampus against tunicamycin - induced cell death . - pubmed
This study retrospectively analyzes the results of arthrolysis and hinged external fixation performed on 15 patients suffering from ankylosed elbows . - pubmed
The in vitro cytotoxicities of both complexes were preliminarily evaluated and the cytotoxicity of complex 1 against the human lung cancer cells ( H1299 ) is similar to oxaliplatin , but higher than transplatin and carboplatin . - pubmed
HSV-1 infection induced cell death as early as 6 h after infection through the necrotic pathway and required de novo protein synthesis in L929 cells . - pubmed
Novel mouse model of chronic inflammatory and overactive bladder by a single intravesical injection of hydrogen peroxide . - pubmed
There is so far no generally accepted animal model of chronic cystitis by which potential therapies can be evaluated . - pubmed
In this study , we aimed to establish a new mouse model of cystitis based on the proinflammatory effects of reactive oxygen species . - pubmed
Management of elderly patients with primary central nervous system lymphoma . - pubmed
Elderly patients , or those over the age of 60 years , represent an important subgroup and account for over half of PCNSL patients . - pubmed
However , chemotherapy is associated with systemic toxicities , such as myelosuppression , to which the older patient is more vulnerable . - pubmed
Radiotherapy is also effective but is limited by significant delayed neurotoxicity , especially in older patients . - pubmed
Most studies support the use of chemotherapy - only treatments for elderly patients given the high risks of neurotoxicity associated with radiotherapy . - pubmed
Acoustic emission based monitoring of the microdamage evolution during fatigue of human cortical bone . - pubmed
The current study aims to assess the time history of the occurrence of AE events during fatigue loading of human tibial cortical bone and to determine the associations between AE variables ( energy content of waves , number of AE waveforms , etc . ) - pubmed
Fatigue test specimens were prepared from the distal diaphysis of human tibial cortical bone ( N = 32 , 22 to 52 years old , male and female ) . - pubmed
[ Dietary patterns in patients with attention deficit hyperactivity disorder ] . - pubmed
OBJECTIVE : To evaluate the dietary patterns in a group of patients diagnosed with attention deficit hyperactivity disorder ( ADHD ) and under treatment with extended - release methylphenidate ( MPH - ER ) . - pubmed
MATERIAL AND METHODS : A nutrition survey ( food intake recall for three consecutive days ) was carried out on 100 patients diagnosed with ADHD and under treatment with MPH - ER , and in 150 healthy children ( control group ) . - pubmed
The consumption of cereals , meat , pulses and fruits in the control group was significantly higher ( P & lt ; .05 ) than in ADHD group . - pubmed
RESULTS : Overall , 301 patients had OPN and 149 LPN . - pubmed
MATERIALS AND METHOD : The study consisted a group of 223 randomly selected asthma patients with varying degrees of asthma control . - pubmed
The incidence and patterns of hardware failure after separation surgery in patients with spinal metastatic tumors . - pubmed
BACKGROUND CONTEXT : Spine metastases occur frequently in patients with cancer . - pubmed
PURPOSE : The purpose of this study was to determine the incidence of symptomatic hardware failure and the associated risk factors in patients with metastatic epidural spinal cord compression ( MESCC ) . - pubmed
PATIENT SAMPLE : The current series analyzes a cohort of 318 patients who underwent separation surgery , which involves single - stage posterolateral decompression and posterior segmental instrumentation for MESCC . - pubmed
RESULTS : Of the 318 patients , nine ( 2.8 % ) exhibited signs and symptoms of hardware failure and required revision of the instrumentation . - pubmed
CONCLUSIONS : The incidence of hardware failure is low in patients with MESCC who undergo posterolateral decompression and posterior screw - rod instrumentation . - pubmed
NOD.IFNAR1(-/- ) mice developed insulitis and diabetes at a similar rate to NOD controls . - pubmed
Successful use of eculizumab in an 86 - year - old patient with paroxysmal nocturnal hemoglobinuria in Japan . - pubmed
Eculizumab was used to treat an 86 - year - old male patient with paroxysmal nocturnal hemoglobinuria , the oldest reported case in Japan . - pubmed
As observed in younger patients , this drug rapidly suppressed hemolysis in the present patient , which allowed weaning from blood transfusion . - pubmed
Despite the patient 's advanced age , the inhibition of complement activity caused by this drug did not result in infection , indicating that it is safe to use in elderly patients . - pubmed
We report an extremely rare case of GIST of the anal canal in 60 - years - old man with history of irregular bowel habits with dark colored stool mixed with blood and constipation from 6 month . - pubmed
The Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention recommends that human papillomavirus ( HPV ) vaccination routinely be targeted to females and males aged 11 years or 12 years as part of the adolescent immunization platform to help reduce the incidence of anogenital cancers and genital warts associated with HPV infection . - pubmed
Obstetrician - gynecologists should advise patients and parents that HPV vaccines are most effective in preventing genital cancers when administered before the onset of sexual activity . - pubmed
OBJECTIVE : To investigate self - reported upper gastric symptoms experienced by patients with chronic kidney disease ( CKD ) and compare associations between uraemic symptoms and saliva composition . - pubmed
METHODS : In a cross - sectional observational study , 30 patients with Stages 4 and 5 CKD were selected from a tertiary hospital renal outpatient clinic . - pubmed
CONCLUSION : Altered saliva composition in patients with Stages 4 and 5 CKD may be associated with uraemic upper GI symptoms . - pubmed
To date , there is a paucity of relevant model systems to critically evaluate how the signature genetic abnormalities detected in human ATC contribute to disease pathogenesis . - pubmed
IMPLICATIONS : This genetically relevant mouse model of ATC will be an invaluable platform for preclinical testing of pathway - targeted therapies for the prevention and treatment of thyroid carcinoma . - pubmed
A 74 - year - old man with intermittent claudication had undergone balloon - expandable stenting for the left CIA . - pubmed
Cytological smears were taken from the lesional site of leukoplakia patients and buccal mucosa of controls . - pubmed
Oxidative stress - mediated cytotoxicity and metabolism of T-2 toxin and deoxynivalenol in animals and humans : an update . - pubmed
Conclusion We have shown that hypoplastic PNH patients can be allografted safely using RIST and that the long - term results are adequate , the cost - benefit ratio of this treatment being reasonable . - pubmed
687 baseline and 30 months follow - up MRIs of the knees of 348 overweight and obese middle - aged women , free of OA at baseline , were scored using the MOAKS . - pubmed
The subjects were evaluated for clinical and radiological outcome who were manifested by back pain alone ( n = 4 ) or back pain with leg pain ( n = 19 ) associated with a primary diagnosis of degenerative spondylolisthesis , massive disc herniation , lumbar stenosis , recurrent disc herniation or degenerative disc disease . - pubmed
Three patients had persistent back pain , 4 patients had residual numbness or radiculopathy . - pubmed
The bowhead whale transcriptome is a valuable resource for the study of this remarkable animal , including the evolution of longevity and its important correlates such as resistance to cancer and other diseases . - pubmed
We assume that in order to increase farmers ' motivation to have their animals immunized against BTV-8 , ( 1 ) the vaccination needs to be subsidized , ( 2 ) combined vaccines with several different BT serotypes or even other diseases should be available and ( 3 ) farmers need to be better informed about the safety and benefit of vaccination . - pubmed
OBJECTIVES : Prognosis for patients with locally advanced esophagogastric adenocarcinoma ( EAC ) is poor with surgery alone , and adjuvant therapy after open esophagectomy is frequently not tolerated . - pubmed
Recurrence patterns were similar between groups and 65 % of patients with IIb or greater pathologic stage received adjuvant therapy . - pubmed
Our data suggest that primary MIE in patients with resectable EAC may be a reasonable approach , improving stage - based prognostication and potentially minimizing overtreatment in patients with early stage disease through accurate stage assignments . - pubmed
The squid ink polysaccharides protect tight junctions and adherens junctions from chemotherapeutic injury in the small intestinal epithelium of mice . - pubmed
Comparative study of renal protective effects of allopurinol and N - acetyl - cysteine on contrast induced nephropathy in patients undergoing cardiac catheterization . - pubmed
MATERIALS AND METHODS : This is a study of 500 patients undergoing angiography and coronary revascularisation in patients showing significant coronary block . - pubmed
RESULTS : CIN occurred in 56 of 500 the patients ( 10.6 % ) who underwent angiography and 49 of 275 patients ( 17.8 % ) who underwent angioplasty . - pubmed
In the omnipaque group CIN occurred in 16/40 , 8/40 , nil/45 in patients receiving SH , NAC plus SH and SH plus ALLP respectively . - pubmed
CONCLUSION : Prophylactic oral administration of allopurinol ( 300 mg / day ) along with hydration is better than n - acetylcysteine and saline hydration alone for protection against CIN in patients undergoing coronary procedures . - pubmed
This study aims to investigate whether attention and spatiotemporal integration deficits are dissociated in patients with bilateral posterior cortical atrophy ( PCA ) , and whether it is their combination that leads to a severe clinical handicap . - pubmed
We recorded performance and ocular behavior of four PCA patients and four age - matched controls in visual search and counting tasks . - pubmed
Nebivolol to attenuate the effects of hyper - homocysteinaemia in rats . - pubmed
METHODS : Prospectively collected clinical and radiological data of 236 AAA patients , treated at our institution between June 2009 and June 2012 , were retrospectively analyzed regarding the number , location and type of SRCs and AWHs . - pubmed
Two hundred thirty - six randomly chosen patients with aortoiliac occlusive disease ( AOD ) were recruited as control group . - pubmed
RESEARCH DESIGN AND METHODS : Acromegaly patients were identified in two commercial claims databases for this retrospective analysis . - pubmed
METHODS AND MATERIALS : Eligible patients had 1 to 3 liver metastases , maximum sum diameter 6 cm , without extrahepatic progression . - pubmed
CONCLUSION : SBRT is effective for selected patients with hepatic oligometastases with limited toxicities . - pubmed
METHODS : Sixty patients with moderate - to - severe plaque psoriasis were randomized to cohort A : 100 mg , 200 mg or 400 mg GSK2586184 twice daily or placebo ; and eight were randomized to open - label cohort B , a small exploratory cohort treated with 400 mg GSK2586184 twice daily , to explore differential gene expression . - pubmed
CONCLUSIONS : Our study demonstrates that 12 weeks of treatment with GSK2586184 resulted in clinical improvement and was generally well tolerated in patients with moderate - to - severe plaque - type psoriasis . - pubmed
Lemierre Syndrome of the Femoral Vein , Related to Fusobacterium necrophorum Abscess of Vastus Lateralis . - pubmed
BACKGROUND : Lemierre syndrome is an uncommon , potentially lethal disorder combining acute oropharyngeal infection caused by Fusobacterium necrophorum , with jugular vein suppurative thrombosis , complicated by anaerobic sepsis with secondary multiple metastatic abscesses . - pubmed
CASE REPORT : We present a clinical case of Fusobacterium necrophorum abscess complicated with femoral vein thrombosis , called atypical localization of Lemierre syndrome . - pubmed
METHOD : Nasal samples were collected from 12 individuals with asthma and 23 healthy controls early and late in a final exam period , and during a low - stress period in the semester . - pubmed
RESULTS : Mixed effects analysis of variance models showed that asthmatic participants with allergies in contrast to healthy individuals experienced a decrease in nasal LTB4 during the final exam period as compared to mid - semester ( low stress period ) . - pubmed
CONCLUSIONS : Our results suggest that nasal LTB4 concentrations change in periods of psychological stress for asthmatic individuals with allergies . - pubmed
To date treatment is unable to alter the natural history of MDS except in those few individuals who are able to undergo allogeneic progenitor cell transplantation . - pubmed
METHODS : Seven phFTD patients without progression or alternative psychiatric diagnosis , 12 bvFTD patients and 17 controls underwent resting state functional MRI ( rs - fMRI ) and diffusion tensor imaging ( DTI ) . - pubmed
Salmonellosis is one of the most important bacterial zoonotic diseases transmitted through the consumption of contaminated food , with chicken and pig related products being key reservoirs of infection . - pubmed
The aim of this study was to evaluate the prognostic significance of total atrial conduction time ( TACT ) assessed by tissue Doppler imaging ( PA - TDI interval ) to predict AF presence in patients with cryptogenic stroke . - pubmed
METHODS : Ninety patients ( 57.7 + - 12.3 years , 48 % women ) after acute cryptogenic stroke and ICM implantation were prospective recruited at four centers for continuous rhythm monitoring . - pubmed
Patients were followed up ( 331 + - 186 days ) for detection of AF ( defined by episode lasting & gt;=30 s ) . - pubmed
RESULTS : AF was detected in 16 patients ( 18 % ) during follow - up ( 331 + - 186 days ) . - pubmed
CONCLUSION : Our data suggest that measurement of TACT could help to predict future AF detection in patients with cryptogenic stroke . - pubmed
CONCLUSION : Given that patients with obstructive anuria can be asymptomatic , urolithiasis should be considered in all patients presenting with anuria . - pubmed
Oral administration of both E / E - SBGS and SBGS significantly suppressed tumor volume and tumor weight without gross toxicity in mice . - pubmed
Reduced - Concentration Clavulanate for Young Children with Acute Otitis Media . - pubmed
Amoxicillin - clavulanate ( A / C ) is currently the most effective oral antimicrobial in treating children with acute otitis media ( AOM ) , but the standard dosage of 90 mg amoxicillin/6.4 mg clavulanate / kg of body weight / day commonly causes diarrhea . - pubmed
We conducted an open - label study in children with AOM who were 6 to 23 months of age . - pubmed
Rates of PDD in children receiving phase 2 and standard regimens were 17 % and 26 % , respectively ( P = 0.10 ) . - pubmed
Coronary abnormalities were especially high in this group of patients ( 46 % ) and 9 patients died ( 13 % ) . - pubmed
METHODS : We analyzed cognitive data from people with incident late - onset Alzheimer 's dementia from a prospective cohort study . - pubmed
Modeling DNA damage - induced pneumopathy in mice : insight from danger signaling cascades . - pubmed
The resulting pro - inflammatory and pro - angiogenic microenvironment triggers a cascade of events that can lead within weeks to a pronounced lung inflammation ( pneumonitis ) or after months to excessive deposition of extracellular matrix molecules and tissue scarring ( pulmonary fibrosis).The use of preclinical in vivo models of DNA damage - induced pneumopathy in genetically modified mice has helped to substantially advance our understanding of molecular mechanisms and signalling molecules that participate in the pathogenesis of radiation - induced adverse late effects in the lung . - pubmed
Here we summarize and discuss published data about the role of danger signalling in the response of the lung tissue to DNA damage and its cross - talk with the innate and adaptive immune systems obtained in preclinical studies using immune - deficient inbred mouse strains and genetically modified mice . - pubmed
Leishmania donovani is the causing agent of visceral leishmaniasis , a common infection that affects millions of people from the most underdeveloped countries . - pubmed
Miltefosine is the only oral drug to treat infections caused by L. - pubmed
Survival after whole brain radiotherapy for brain metastases from lung cancer and breast cancer is poor in 6325 Dutch patients treated between 2000 and 2014 . - pubmed
BACKGROUND : Whole brain radiotherapy ( WBRT ) is considered standard of care for patients with multiple brain metastases or unfit for radical treatment modalities . - pubmed
METHODS : Between 2000 and 2014 , 6325 patients had WBRT ( 20 Gy in 4 Gy fractions ) for brain metastases from non - small cell lung cancer ( NSCLC ; 4363 patients ) or breast cancer ( BC ; 1962 patients ) ; patients were treated in 15 out of 21 Dutch radiotherapy centres . - pubmed
FINDINGS : The median survival was 2.7 months for NSCLC and 3.7 months for BC patients ( p & lt ; .001 ) . - pubmed
For NSCLC patients aged & lt;50 , 50 - 60 , 60 - 70 and & gt;70 years , survival was 4.0 , 3.0 , 2.8 and 2.1 months , respectively ( p & lt ; .001 ) . - pubmed
For BC patients , survival was 4.5 , 3.8 , 3.2 and 2.9 months , respectively ( p = .047 ) . - pubmed
INTERPRETATION : The survival of patients after WBRT for brain metastases from NSCLC treated in Dutch ' common radiotherapy practice ' is poor , in breast cancer and younger patients it is disappointingly little better . - pubmed
Over a period of 12 years ( January 2000 - January 2012 ) , a total of 110 patients with hyperactive muscles over the frontal region have been collected for a retrospective study . - pubmed
Toward a noninvasive estimate of interstitial fluid pressure by dynamic contrast - enhanced MRI in a rat model of cerebral tumor . - pubmed
PURPOSE : This study demonstrates a DCE - MRI estimate of tumor interstitial fluid pressure ( TIFP ) and hydraulic conductivity in a rat model of glioblastoma , with validation against an invasive wick - in - needle ( WIN ) technique . - pubmed
METHODS : The DCE - MRI studies were conducted in 36 athymic rats ( controls and posttreatment animals ) with implanted U251 cerebral tumors , and with TIFP measured using a WIN method . - pubmed
DREADDed microglia in pain : Implications for spinal inflammatory signaling in male rats . - pubmed
Samples from 45 chickens , two turkeys , one peacock and one quail with symptoms of fowlpox were collected in Mozambique between November 2016 and January 2018 . - pubmed
The baseline oral health status of the enrolled patients was poor and included edentulism , caries , gingivitis , periodontitis and residual roots . - pubmed
In addition , innovatively therapeutic strategy of daily drinking PAW on inflammatory - related diseases based on animal disease models is demonstrated , examples being chronic kidney disease ( CKD ) , chronic sleep deprivation ( CSD ) , and lung cancer . - pubmed
A total of 252 parasymphyseal fractures in 200 patients were selected for the study over the period of seven years ( January 2010 - January2017 ) and divided randomly into two groups . - pubmed
Postoperative paraesthesia , infection , and acceptability of the plate to patients were also recorded . - pubmed
Operations were significantly shorter , and significantly fewer patients developed paraesthesia or infection , in the customised group . - pubmed
Epidemiological investigation and nutritional intervention of anthocyanins have exhibited broad - spectrum biological effects that they can benefit patients with metabolic syndrome related chronic diseases . - pubmed
Results : An industry - like SCJ - VHG bioethanol production process with 30 and 35 Bx broth was employed to investigate the effects of both the yeast strain used and nitrogen source supplementation on process yield , process productivity , biomass viability , glycerol concentration and retention - associated gene expression . - pubmed
Highest process efficiency , with a 17 % ( w / v ) ethanol yield and only 0.2 % ( w / v ) sugar remaining unfermented , was observed with the Saccharomyces cerevisiae industrial strain CAT-1 in 30 Bx broth with urea supplementation . - pubmed
SCJ concentrated up to 30 Bx maintains industrially relevant ethanol production yield and productivity , provided the broth is supplemented with a suitable nitrogen source and an appropriate industrial bioethanol - producing yeast strain is used . - pubmed
In addition , the work contributes to a better understanding of the VHG - SCJ process and the variable effects of process parameters on process efficiency and yeast strain response . - pubmed
Impact of Sensor - Augmented Pump Therapy with Predictive Low - Glucose Suspend Function on Glycemic Control and Patient Satisfaction in Adults and Children with Type 1 Diabetes . - pubmed
AIMS : The aim was to evaluate the effectiveness of sensor - augmented pump therapy with predictive low - glucose suspend function ( SAP - PLGS ) in real - world use in children and adults with type 1 diabetes ( T1D ) . - pubmed
METHODS : Patients with T1D treated with the MiniMed 640 G pump with PLGS function at three referral hospitals were retrospectively evaluated . - pubmed
Mean age was 32 + - 17 years , 28 % were ( n = 46 ) children , and 29 % ( n = 47 ) were with a history of severe hypoglycemia . - pubmed
Three percent ( n = 5 ) of the patients experienced severe hypoglycemia during follow - up . - pubmed
A total of 22 participants presented for re - treatment of a previously ruptured ( & gt;30 days prior to treatment ) target aneurysm . - pubmed
Medline , Embase , the Cochrane controlled trials register , the SCI , ASH , EHA , and ASCO were searched for clinical trials including high - dose chemotherapy plus ASCT for patients with NDMM . - pubmed
ASCT could improve survival than alkylating agent - based regimens plus lenalidomide consolidations for patients with NDMM . - pubmed
The second patient was diagnosed with lipomyelomeningocele during an examination for severe constipation at the age of 2 years and 8 months . - pubmed
Bombyx mori bidensovirus infection alters the intestinal microflora of fifth instar silkworm ( Bombyx mori ) larvae . - pubmed
Bacterial diseases can occur as a result of disruption of the intestinal microbial population in the silkworm , Bombyx mori , and are often induced by bidensovirus ( BmBDV ) infection . - pubmed
The research of transgenic human nucleus pulposus cell transplantation in the treatment of lumbar disc degeneration . - pubmed
Immumohistochemical staining , RT - PCR , and western blot were performed to observe the biological effects of double gene - transfected human nucleus pulposus cells in degenerative lumbar discs on rhesus lumbar disc degeneration . - pubmed
Timely detection the side effects of statins makes it possible to diagnose and eliminate , which is crucial for conducting lipid - lowering therapy for patients with atherosclerotic cardiovascular diseases . - pubmed
Escherichia coli was recovered in 34.1 % of culture - positive UTI episodes , followed by Proteus mirabilis and Klebsiella spp , which were recovered in 24.5 % and 17.4 % of culture - positive UTI episodes , respectively . - pubmed
Extensive Fatty Replacement of the Pancreas ( Pancreatic Lipomatosis ) in a Dog . - pubmed
A 12 - year - old neutered female mixed - breed dog was referred for occasional vomiting that had increased progressively in frequency over the past 3 months . - pubmed
Routine follow - up with the referring veterinarian showed no evidence of postoperative complications , but the dog continued to deteriorate further and died despite medical management . - pubmed
Pancreatic lipomatosis is a rare condition in small animal practice . - pubmed
Meanwhile , all isolated compounds were evaluated for their immunosuppressive activities against mice splenocyte proliferation and antiproliferative activities against human gastric adenocarcinoma cells ( SGC-7901 ) , human hepatoma ( HepG2 ) , and human breast cancer ( MCF-7 ) in vitro . - pubmed
In - vivo cortical thickness estimation from high - resolution T1w MRI scans in healthy and mucopolysaccharidosis affected dogs . - pubmed
Preliminary results of 5 healthy and 5 mucopolysaccharidosis ( MPS ) dogs demonstrate single - canine mean / median cortical thickness in range of 2.69 - 3.58 mm in native space and 3.26 - 4.15 mm in template space . - pubmed
RESULTS : A total of 212 type 2 diabetic patients aged 40 years or more , and 209 age - matched nondiabetic subjects were included in the study . - pubmed
About one - quarter of the diabetics and nondiabetics were positive for H. - pubmed
We present an unusual case of a 60 - year - old woman with myasthenia gravis , who was diagnosed with an incidental thymoma found on computerised tomography . - pubmed
METHODS : Patients with RA ( symptom duration < 2 years ) were included from two randomised trials : BehandelStrategieen ( BeSt ) , n=508 and Induction therapy with Methotrexate and Prednisone in Rheumatoid Or Very Early arthritic Disease ( IMPROVED ) , n=479 . - pubmed
METHODS : Patients treated with radiotherapy for localized SCCA were included in Aarhus , Denmark from 2016 -2019 . - pubmed
Baseline levels for patients with treatment failure ( n=8 ) were above the 25th percentile ( p=0.05 ) which translates into difference in disease free survival . - pubmed
If successful , the proposed tools will provide practical screening and streamlined , comprehensive assessments that could be implemented in resource - limited settings to identify children with cognitive deficits within programmes focused on the care and treatment of children affected by HIV . - pubmed
CONCLUSION : Our study shows that overexpression of immunohistochemical parameters together with the negative effects of ischemic and inflammatory processes that subjected to pBOO for 1 , 2 and 3 weeks may play a potential role in detrusor fibrosis in the rat bladders induced by pBOO . - pubmed
H7N9 influenza A virus ( IAV ) is an emerged contagious pathogen that may cause severe human infections , even death . - pubmed
Circular RNAs ( circRNAs ) have been reported to affect the development of human cancers , including HCC . - pubmed
Patients in PG had significantly more often undergone neuroma resection or stump revision surgery . - pubmed
The use of dynamic MR - imaging in patients with clinical pelvic floor disorders . - pubmed
METHODS : Fifty patients ( 44 females , 6 males ; mean age : 57 years ) with symptomatic pelvic floor dysfunction underwent both examinations , CD and MRD . - pubmed
, enterotoxigenic Escherichia coli , Clostridium difficile , Cryptosporidium parvum , Entamoeba histolytica , and Hepatitis A virus . - pubmed
METHODS : We tested this hypothesis in the Personalized Prevention of Colorectal Cancer Trial ( PPCCT ) ( registered at clinicaltrials.gov as NCT01105169 ) , a double - blind 2 x 2 factorial randomized controlled trial enrolling 240 participants at high risk of Mg deficiency . - pubmed
From March 1975 until September 1978 , seventy patients were referred for intra - aortic balloon counterpulsation for cardiogenic shock complicating acute myocardial infarction or for the treatment of low cardiac output states following cardiopulmonary bypass . - pubmed
Effects on in vitro tumor growth of murine macrophages isolated from sarcoma lines differing in immunogenicity and metastasizing capacity . - pubmed
Macrophages were isolated from the strongly immunogenic , non - metastasizing FS6 sarcoma transplanted in syngeneic C57BL / 6 mice and from a weakly immunogenic , spontaneously metastasizing line ( mFS6 ) of the same tumor . - pubmed
Of 200 girls having recurrent urinary tract infection 43 per cent showed ureterovesical reflux on the cystogram . - pubmed
Of 39 boys with recurrent urinary tract infection 41 per cent had reflux . - pubmed
Letter : Haloperidol for acute amphetamine poisoning : a study in dogs . - pubmed
[ Activation of pulmonary macrophage in early stage of experimental acute pancreatitis in rat : preliminary report ] . - pubmed
This is also true with fibromas because many types of fibromas would require suturing that would create an inconvenience for the patient . - pubmed
CO2 laser surgery performed on the punctata aeriata , interdigital clavus formations , and hypertrophic scars are not always as successful but offer the surgeon another modality in taking care of the patient 's problems without the need for extensive surgery . - pubmed
The cumulative dose response effect of eicosapentaenoic and docosahexaenoic acid on blood pressure , plasma lipid profile and diet pattern in mild to moderate essential hypertensive black patients . - pubmed
In this study eicosapentaenoic acid ( EPA ) and docosahexaenoic acid ( DHA ) were given in a cumulative manner , every 6 weeks , starting with 10 mg , then 100 mg , 1000 mg and 10,000 mg EPA daily to mild to moderate essential hypertensive black patients . - pubmed
It is therefore concluded that EPA and DHA supplementation had no beneficial effects in mild to moderate essential hypertensive black patients except for a lowering of plasma AA . - pubmed
We describe a young man with radiographic evidence of early onset bullous emphysema without the usual risk factors and provide a review of the alternative explanations proposed for this form of lung damage . - pubmed
We evaluated the neuropsychological functions , rate of disease progression , and psychiatric characteristics of 22 patients with probable Alzheimer ' s disease in whom periventricular white - matter radiolucencies ( PWMRs ) were seen on the computed tomographic scan of the brain and compared them with 22 matched patients with Alzheimer ' s disease without PWMRs . - pubmed
However , patients with PWMRs had significantly higher Hachinski Rating scores at both visits and were more likely to develop cerebrovascular disease during follow - up than were controls with Alzheimer ' s disease . - pubmed
Chemoresistance in rat ovarian tumours . - pubmed
In a cisplatin resistant subline ( O-342 / DPP ) of an intraperitoneally growing transplantable rat ovarian tumour ( O-342 ) , intracellular glutathione ( GSH ) was approximately doubled ( mean [ S.E. ] - pubmed
From the sequence information , a synthetic peptide was synthesised which was recognised by one of the monoclonal antibodies directed against the 14 - kDa antigen and a small number of sera from patients with onchocerciasis . - pubmed
After the patients had been anaesthetized for some time and were haemodynamically stable , profound bradycardia or ventricular asystole occurred suddenly in response to manipulations of the bony structures of the maxilla or mandible , or dissection of , or traction on , the attached soft tissue structures . - pubmed
All patients undergoing maxillofacial procedures should be monitored carefully for reflex bradycardia and ventricular asystole . - pubmed
In four of these nine patients there was evidence of an accessory esophageal disease responsible for the chest pain . - pubmed
In 44 patients organic or functional ischemic heart disease was excluded . - pubmed
The final results were that 15 patients had pain of an esophageal origin and 13 had an esophageal disease that made the esophagus a likely , or at least possible , source of pain . - pubmed
Biological markers characterizing the development of preneoplastic and neoplastic lesions in rodent liver . - pubmed
Although no distinct single biochemical marker is ubiquitous to the process of neoplasia or even to a single histogenetic type of neoplasm , a variety of histogenetic types of neoplasms in the human and experimental animals exhibit an extreme degree of marker or phenotypic heterogeneity . - pubmed
Particularly well studied are markers which occurred during the process of hepatocarcinogenesis in the rodent as well as in its final product , the hepatoma . - pubmed
Although phenotypic heterogeneity is characteristic of hepatocellular carcinomas in both the rat and mouse , some degree of predominant marker pattern(s ) has become apparent . - pubmed
Studies on the transcription of specific genes in mouse liver as well as preneoplastic and neoplastic lesions in this tissue further demonstrate the phenotypic heterogeneity characteristic of differentiated hepatocellular carcinomas . - pubmed
In general , current evidence supports the two these s that no single biologic marker or set of markers is uniquely characteristic of the preneoplastical and/or neoplastic phenotype and marker or phenotypic heterogeneity is by far the rule rather than the exception in hepatocarcinogenesis in the rodent and quite possibly in all histogenetic types of neoplasms in mammals . - pubmed
Sodium chloride depletion in a cat with fistulated meningomyelocele . - pubmed
Decreased serum and CSF chloride concentrations were documented in a 5 - year - old Manx cat referred for evaluation of anorexia . - pubmed
Spinal trabecular bone mineral content in patients with non - steroid treated rheumatoid arthritis . - pubmed
Spinal trabecular bone mineral content was measured in the first , second , and third lumbar vertebrae by quantitative computed tomography in 88 patients with non - steroid treated rheumatoid arthritis . - pubmed
One vertebral crush fracture was found in one patient but not in any of the controls . - pubmed
These results demonstrate a lower spinal trabecular bone mineral content in non - steroid treated patients with rheumatoid arthritis than in age and sex matched controls , the difference being most marked in younger patients . - pubmed
Alterations of electroencephalogramm and evoked potentials in brain dead patients are known . - pubmed
So we analysed those comatose patients requiring for artificial respiration in whom brain stem acoustic responses could not be evoked . - pubmed
We found 21 patients out of 103 unselected consecutive patients with primary cerebral disease . - pubmed
All patients with isoelectric EEG were brain dead . - pubmed
Earlier SSEP components were frequent , deformed flash evoked potentials were found in all brain dead patients . - pubmed
In all brain dead patients there was an absence of early acoustic evoked responses and an isoelectric electroencephalogramm . - pubmed
The Medical Research Council UKALL V trial for children with standard - risk acute lymphoblastic leukemia ( ALL ) ( aged 1 to 14 years , leucocyte count less than 20 X 10(9)/L ) was designed to determine whether the immunosuppressive effects of treatment could be reduced without sacrifice of antileukemic effect by alterations in the type of continuing therapy or in fractionation of cranial irradiation . - pubmed
With a minimum follow - up of almost 7 years , patients in group I had significantly fewer remission deaths ( P = .025 ) but a much higher rate of bone marrow relapse than those in group C or G ( P = .002 ) . - pubmed
47 children have been treated in Basel for aganglionosis ( Hirschsprung ' s disease ) during the last 25 years . - pubmed
Six children presented severe vomiting and an ileus as leading symptoms instead of chronic constipation , the classical leading symptom of Hirschsprung ' s disease . - pubmed
However , enzyme histochemical and immunocytochemical investigations disclosed an aganglionosis of the entire colon ( Zuelzer - Wilson ' s disease ) in 3 patients , absence of the enteric nervous system in the small and large intestine in 2 patients , and a combination of both in 1 patient . - pubmed
In contrast to children suffering from aganglionosis of the entire colon , the chance of survival for patients with an absence of the enteric nervous system is extremely small . - pubmed
Constitutional predisposition to vasovagal syncope : an additional risk factor in patients exposed to electrical injuries ? - pubmed
An hour after a 220 V electric shock a patient who was susceptible to mild vasovagal symptoms in response to emotional stress had a severe episode of cardiac arrest in response to insertion of a cannula . - pubmed
Patients with a history of vasovagal reactions may be at high risk of developing lethal sinus node or conduction disturbances after electrical injuries . - pubmed
To clarify the controversy over whether the neonatal heart is more or less susceptible to global ischemia than the adult heart , the time interval between the onset of ischemia and the beginning of contracture ( TIC ) was compared in neonatal ( n = 6 , 3 to 5 days old ) and adult ( n = 6 , 4 to 5 months old ) pig hearts . - pubmed
Body surface potential maps were recorded from 140 lead points on the entire chest surface in three groups of subjects : group A consisted of 15 patients with an old inferior myocardial infarction and typical electrocardiographic signs of necrosis ; group B consisted of 15 patients with an old inferior myocardial infarction , but without electrocardiographic signs of necrosis ( inferior myocardial infarction was documented during the acute phase ) ; group C consisted of 30 healthy controls . - pubmed
In a randomized trial 49 patients with fracture of the neck of the femur and an age of less than 70 years or a high level of physical activity were allocated to treatment with a sliding screw plate or a sliding nail plate fixation . - pubmed
The effect of acute metabolic or respiratory acid - base disturbances on biliary bicarbonate secretion was examined in bile fistula rats . - pubmed
I. Biliary and urinary excretion in normal rats and with experimental liver injury ] . - pubmed
[ Influence of chronic intermittent hemodialysis on lymphocyte stimulation by PHA in patients with terminal kidney failure ] . - pubmed
Biochemical and electrophoretic studies of -galactosidase in normal man , in patients with Fabry ' s disease , and in Equidae . - pubmed
[ Upper digestive hemorrhages in patients with gastroduodenal ulcer after administration of ulcerogenic drugs ] . - pubmed
An experimental comparison between the ganglion cell receptive field and the receptive field of the adaptation pool in the cat retina . - pubmed
Strain differences in susceptibility of mice and rats to cadmium - induced testicular damage . - pubmed
Understanding the adaptive struggles of schizophrenic patients . - pubmed
Reactivity of sera from sheep immunised with individual outer membrane proteins of Bacteroides nodosus against heterologous bacterial strains . - pubmed
In order to identify those bacterial antigens which might be involved in immunity against ovine footrot , antisera were raised in sheep to 6 proteins in the outer membrane complex ( OMC ) of one strain of Bacteroides nodosus . - pubmed
Subsequent analysis of these sera against 5 strains of B. - pubmed
Accessory cell function in tumor - bearing mice and effects of Corynebacterium parvum . - pubmed
For investigation of the mechanism of the immunosuppression in tumor - bearing mice and the effects of C. - pubmed
parvum , the accessory cell function of adherent cells from tumor - bearing mice and C. - pubmed
parvum - treated tumor - bearing mice in in vitro cultures was studied . - pubmed
Peritoneal and splenic cells from tumor - bearing mice were less efficient in promoting in vitro production of antibody to SRBC by macrophage - depleted normal nonadherent cells than the adherent cells from normal mice . - pubmed
parvum treatment restored the accessory cell function of splenic adherent cells from tumor - bearing mice but not that of peritoneal cells . - pubmed
Furthermore , adherent cells from tumor - bearing mice did not show suppressive activity against the in vitro plaque - forming cell response . - pubmed
This is a retrospective study of 18 acute traumatic tetraplegic patients admitted to the Cardiff Royal Infirmary within 12 hours of injury . - pubmed
Ultraviolet light and mitomycin C induced sister - chromatid exchanges in fibroblasts from patients with retinoblastoma . - pubmed
A standard feeding procedure may be useful in evaluating dogs with gastrinoma . - pubmed
Effects of systemic hypertension on ischemic and nonischemic regional left ventricular function in awake , unsedated dogs after experimental coronary occlusion . - pubmed
Hypertension and atherosclerotic coronary arterial obstruction frequently coexist in patients . - pubmed
Systemic hypertension resulted in a significant increase in endocardial and midwall RMBF and , in seven open - chest dogs , decreased the intramyocardial accumulation of carbon dioxide after LAD occlusion . - pubmed
Thus , the production of systemic hypertension with diastolic pressures of 110 - 120 mm Hg acutely or for 6 hours during evolving canine myocardial infarction does not appear to exert an important deleterious effect on myocardial oxygen supply and demand . - pubmed
A young man with visual defect and galactorrhea . - pubmed
More than 100 lesions in 38 patients were treated with radiation alone and hyperthermia in combination with radiation . - pubmed
Experimental studies on laboratory rats have shown that solvent mixtures with n - hexane and methyl - ethyl - ketone bring about an earlier onset of clinical - neurological deficits and hexacarbon - specific morphological changes than exposure to n - hexane alone . - pubmed
Hepatic lesions in Lebistes reticulatus induced by N - nitrosodiethylamine . - pubmed
In the later period of the experiment , hyperplastic nodules of hepatocytes , cholangiofibrosis , cystic cholangiomas , hepatocellular and cholangiocellular carcinomas could be observed in the treated animals . - pubmed
Aquarium fish can be used as a model for short - term , in vivo carcinogenesis experiments . - pubmed
Lebistes reticulatus is a suitable strain for use as a positive control with NDEA . - pubmed
Thirty - three subjects were studied : 6 normal subjects , 12 with chronic pancreatitis , 3 after recovery from acute pancreatitis , 8 with gall - stones , 3 with carcinoma of the pancreas and 1 with cancer of the biliary tract . - pubmed
The animals were killed forty - two and eighty - four days after the injury . - pubmed
Lipid abnormalities are seen frequently in renal transplant patients . - pubmed
Cardiovascular disease is an important cause of morbidity and mortality in these patients . - pubmed
Twelve renal transplant patients who had persistent hyperlipidemia despite 6 weeks of dietary treatment participated in this prospective , randomized , open - labeled crossover trial . - pubmed
Although flushing developed in 67 % of patients treated with nicotinic acid , this was not a reason for any of the study dropouts . - pubmed
administration of 10 mg / kg body weight to woodchucks and Pekin ducks . - pubmed
MATERIAL AND METHODS : From 1979 to 1982 34 patients underwent surgical correction of a flexion deformity of the spine in ankylosing spondylitis . - pubmed
Moreover , the degradation products of as - polymerized PLLA bone plates , consisting of numerous stable particles of high crystallinity , are related with a subcutaneous swelling in patients 3 yr postoperatively . - pubmed
Although turtles can serve as alternate hosts for Salmonella , available evidence suggests that turtles in tanks should not be a source of human infection . - pubmed
A novel translocation , t(5;14)(q33 - 34;q11 ) , was identified in the leukemic cells of four children presenting with acute lymphoblastic leukemia ( ALL ) . - pubmed
The patients were 14 months , 2 years , 10 years , and 12 years old ; each presented with one or more features of bulky disease , including lymphadenopathy , organomegaly or a mediastinal mass . - pubmed
The patients with B - lineage ALL remain in continuous remission at 22 and 19 months following diagnosis . - pubmed
One patient with T - lineage ALL relapsed 6 months after diagnosis . - pubmed
The other patient with T - lineage ALL developed acute myelocytic leukemia ( AML ) 17 months after diagnosis ; t(5;14)(q33 - 34;q11 ) was present in both the lymphoblasts at diagnosis and the myeloblasts at relapse , consistent with a lineage switch from ALL to AML . - pubmed
Microsatellite mutation ( CAG24 - ->18 ) in the androgen receptor gene in human prostate cancer . - pubmed
Using the polymerase chain reaction ( PCR ) , we screened 40 human prostate cancer specimens for expansions or deletions of this microsatellite . - pubmed
MATERIALS AND METHODS : We retrospectively reviewed the radiographs of 80 patients with pathologically proved gastric carcinoma who had double - contrast barium studies of the upper gastrointestinal tract between 1985 and 1992 . - pubmed
The dermatomes below the Th9 lost all somatic sensation on the left side after the nerve blocks , but the patient was not completely relieved from the pain . - pubmed
OBJECTIVE : To study whether fasting and 1 - h postbreakfast C - peptide levels in NIDDM stabilize with time in individual patients . - pubmed
During the treatment of patients with renal failure or renal transplants the most important consideration is to eliminate sources of infection before and after the treatment . - pubmed
Flow cytometric analysis of neoplastic nodules and hepatocellular carcinomas induced by ciprofibrate in the rat . - pubmed
Thus , to investigate the role of DNA ploidy changes in development of HCC , flow cytometric DNA content determinations were done in a rat model system of peroxisome proliferator - induced HCC . - pubmed
CONCLUSION : Laparoscopic appendectomy has significant advantages in terms of patient comfort and length of stay , and its overall complication rate seems to be lower than with open procedures ; however , its rate of intra - abdominal abscess may actually be higher . - pubmed
[ Study on obstructive causes of internal arteriovenous fistula and prevention in hemodialysis patients ] . - pubmed
The interaction between human endothelial cells ( EC ) and leukocytes during inflammation is in part mediated through the release of soluble factors . - pubmed
Fatal postoperative airway obstruction in a patient with rheumatoid arthritis . - pubmed
We report here the first case of symptomatic acute hepatic injury due to midecamycin in a 58 - year - old man . - pubmed
Thymic lymphoepithelioma - like carcinoma associated with thymoma in a patient with ocular myasthenia . - pubmed
A 65 - year - old woman with ocular myasthenia was found to have three tumours in the anterior mediastinum , revealed by magnetic resonance imaging . - pubmed
METHODS : From January 1 , 1993 , to December 31 , 1997 , all new patients diagnosed with collagenous or lymphocytic colitis living in the catchment area of the Hospital Mutua de Terrassa ( Barcelona , Spain ) were identified . - pubmed
Since 1993 all patients with chronic diarrhea were referred for a diagnostic colonoscopy . - pubmed
Normal rectal biopsies were found in 43 % and 8 % of patients with collagenous and lymphocytic colitis , respectively . - pubmed
To address this and emphasize the role of testicular - sparing surgery in children , four patients with testicular masses are presented who underwent this procedure . - pubmed
RESULTS : Four patients whose ages at diagnosis were 1 , 2 , 4 , and 17 years presented with unilateral testicular masses . - pubmed
It is a viable and useful method in the management of benign testicular tumors in children . - pubmed
We present a case of spontaneous rupture of a right coronary bypass vein graft in a 57 - year - old woman 10 years after coronary by - pass surgery . - pubmed
HBO patients with intractable ETD currently are treated by tympanostomy tube placement ; typically , these tubes are indwelling far longer than is required by the duration of HBO . - pubmed
Only 1 patient had otorrhea ; this resolved with dry ear precautions . - pubmed
Role of nitric oxide in the autoregulation of renal blood flow and glomerular filtration rate in aging spontaneously hypertensive rats . - pubmed
Autoregulation of renal blood flow ( RBF ) and glomerular filtration rate ( GFR ) is well maintained in the spontaneously hypertensive rat ( SHR ) . - pubmed
The results indicate that in hypertensive rats with renal hypertensive damage , the GFR autoregulation is strongly NO dependent , as doses of L - NMMA that do not interfere with the RBF have an effect on the GFR autoregulation . - pubmed
Findings from immunization experiments using animal models of experimental endocarditis support the notion that vaccine development is appropriate for study in humans , and these findings are reviewed in this paper . - pubmed
We describe a case of symptomatic acute infection with HCV in a woman whose sexual partner had chronic hepatitis C. - pubmed
The patient cleared HCV RNA 8 weeks after the onset of acute hepatitis and was found to be persistently HCV - RNA negative during 90 weeks of follow - up . - pubmed
The resolution of acute hepatitis C in this case was probably related to the host rather than to intrinsic characteristics of the HCV genome . - pubmed
Seven children ( 0.2 % ) were visually handicapped ( visual acuity & lt;/=0.3 in the better eye ) . - pubmed
Alterations of the normal bacterial flora on the exterior genitalia may cause the growth of opportunistic bacteria such as Klebsiella pneumonia , Pseudomonas aeruginosa , Streptococcus zooepidemicus , which , if inseminated , may cause infertility in susceptible mares . - pubmed
Contagious equine metritis ( CEM ) , a highly transmissible , true venereal disease of horses , is caused by the gram - negative coccobacillis , Taylorella equigenitalis . - pubmed
Viruses : Equine coital exanthema ( equine herpes virus type 3 ; EHV-3 ) is a highly contagious virus that causes painful lesions on the stallion 's penis and mare 's vulva . - pubmed
Protozoa : Dourine , caused by Trympanosoma equiperidum , is a venereal disease found only in Africa , South and Central America and the Middle East . - pubmed
Piroplasmosis , a disease caused by Babesia equi or by a less severe strain , Babesia caballi , has received a great deal of attention in recent years due to the increased transfer of horses between countries . - pubmed
As a group , children and adolescents with epilepsy have a higher prevalence of cognitive and behavioral disorders , although many fall within the normal distribution . - pubmed
Although certain drugs appear more likely to be involved , no single drug causes problems in every patient , and no drug can be assumed never to cause any cognitive impairment . - pubmed
We report a patient with a myelopathy in primary Sjogren ' s syndrome , proven by salivary gland biopsy and specific antibodies . - pubmed
Under a treatment with azathioprine and prednisone the patient has suffered no relapse within the last 20 months . - pubmed
Dynamics of maternal antibodies to hemorrhagic disease viruses ( Reoviridae : Orbivirus ) in white - tailed deer . - pubmed
Enzootic stability , potentially associated with acquired resistance and subsequent transfer of maternal antibodies , innate resistance , or both , has been hypothesized to explain the lack of reports of hemorrhagic disease ( HD ) in white - tailed deer ( Odocoileus virginianus ) from Texas . - pubmed
The objectives of this research were to determine the following : how long maternal antibodies to epizootic hemorrhagic disease ( EHD ) and bluetongue ( BT ) viruses persist ; whether fawns from an enzootic site are naturally exposed to EHD and BT viruses while maternal antibodies are present ; and whether field - challenged fawns develop clinical disease . - pubmed
This may be due to acquired immunity and the subsequent transfer of maternal antibodies , but it does not exclude innate resistance as a possible factor in the enzootic stability of EHD and BT viruses at this location . - pubmed
Repeat lumpectomy for patients with ipsilateral breast tumor recurrence after breast - conserving surgery . - pubmed
Of 41 patients who had developed IBTR from October 1986 to June 2000 at our institute , 11 underwent mastectomy of the remaining breast and 30 underwent repeat lumpectomy . - pubmed
IBTRs in the majority of our patients were small lesions less than 1 cm in diameter . - pubmed
The person currently in most need of an objective viewpoint on AIDS research , including an outlook on the past , as well as the present and future , is the person who is infected with HIV . - pubmed
It delineates potential areas of concern for the HIV infected patient in the present and future , which may be important directions in the fight against HIV , both for treatment to evolve to the ideal and for an economically viable treatment for the Third World . - pubmed
OBJECTIVE : Stroke is a major complication after coronary surgery , occurring in 1 - 4 % of the patients . - pubmed
METHODS : Data from 4567 patients submitted to isolated coronary artery bypass grafting ( CABG ) with hypothermic ventricular fibrillation between 1992 and 2001 were entered prospectively into a dedicated computerized database and analyzed retrospectively at this time . - pubmed
RESULTS : The incidence of postoperative CVA was 2.5 % ( 116 patients ) . - pubmed
The 30 - day mortality for patients who experienced a CVA was 16.4 % versus 0.6 % for patients who did not ( P<0.001 ) . - pubmed
Postoperative CVA increased the length of hospital stay threefold to 20.3+/-28.3 days as compared with patients who did not have a postoperative CVA ( 7.6+/-4.2 days ; P<0.001 ) . - pubmed
OBJECTIVES : To determine the number of children with severe brain injury due to closed head injury or hypoxic - ischemic encephalopathy as a proportion of all admissions of children & lt;3 yrs of age in the regional pediatric intensive care unit ; to determine the outcome of these children at & gt;6 mos postinjury ; and to explore the relationship of outcome measures to predictors of outcome obtained within the first 24 hrs after brain injury . - pubmed
PATIENTS : Of a cohort of 53 children of & lt;3 yrs of age ( 4 % of pediatric intensive care unit admissions , 1995 - 1998 ) admitted for severe acquired brain injury ( Glasgow Coma Score , & lt;or=8 ) , 12 ( 23 % ) died , three ( 6 % ) were lost to follow - up , and 38 ( 71 % ) survived and received multidisciplinary outcome assessments . - pubmed
In patients with mitral valve prolapse stress induced mitral regurgitation has high predictive power for unfavorable clinical course . - pubmed
Role of nitric oxide in hemodialysis - related hypotension in an experimental renal dysfunction dog model . - pubmed
In order to create a renal dysfunction model , gentamicin was administered to male beagles in which 7 of 8 renal artery branches had been ligated . - pubmed
In renal dysfunctional dogs , a continuous hypotension occurred with a gradual increase in the plasma NOx concentration during HD . - pubmed
These results suggest that NO contributes to HD - related hypotension in renal dysfunctional dogs but the plasma NOx concentration does not reflect the change in blood pressure . - pubmed
The sample was composed by 112 Spanish human services professionals who work with mentally retarded people . - pubmed
[ Terminal ileitis in a young man with Schoenlein - Henoch purpura ] . - pubmed
METHODS : We prospectively studied 50 CVT patients from Brazil , comparing clinical and laboratory data among white ( W ) and African - Brazilian ( AB ) patients . - pubmed
RESULTS : Seventy percent of the patients were female , 26 W and 23 AB , mean age 34.7 years . - pubmed
Losartan increases bradykinin levels in hypertensive humans . - pubmed
Non - neoplastic process after neck dissection demonstrated on enhanced CT in patients with head and neck cancer . - pubmed
Non invasive evaluation of endothelial function in patients with Anderson - Fabry disease . - pubmed
Patients ' exclusion criteria included a prior history of cardiac disease , diabetes and treated or untreated hypertension . - pubmed
Patients underwent : anamnesis , physical examination , EKG , 2 - dimensional echocardiography with tissue Doppler , measurement of body weight and height , blood pressure . - pubmed
CONCLUSIONS : Our study demonstrated the presence of endothelial dysfunction in patients with Fabry ' s disease in comparison to controls . - pubmed
We hypothesized that endothelial dysfunction may contribute to the pathogenesis of ischemic events in patients with Fabry ' s disease . - pubmed
This paper presents two patients with rhinocerebral mucormycosis , both suffering from diabetes . - pubmed
Complete recovery was achieved in one patient with surgical debridement of necrotic tissue combined with systemic antifungal treatment , whereas in the other , the disease was complicated with subarachnoid hemorrhage and the patient died on the third day of treatment . - pubmed
A 64 - year - old man with unresectable sigmoid adenocarcinoma due to peritoneal dissemination ( P3 ) and liver metastasis ( H2 ) treated with TS-1 , showed a complete response . - pubmed
OBJECTIVE : To study the effects of a special nutritional supplement on bone mineral density and bone turnover markers in Chilean elderly subjects with femoral osteoporosis . - pubmed
SUBJECTS : Free living elderly subjects with femoral osteoporosis . - pubmed
In addition , emerging pathogens such as BK polyomavirus and West Nile flavivirus infections and the introduction of newer immunosuppressive agents that constantly change the risk profiles for opportunistic infections has added layers of complexity to this burgeoning field . - pubmed
Most of the reviews described in detail several aspects of HIV tropism , viral entry mechanism , coreceptor usage and its implication on disease progression , antiretroviral therapy , and vaccine development . - pubmed
Protective effects of hyperoxygenated solution preconditioning on intestinal ischemia - reperfusion injury in rabbits . - pubmed
BACKGROUND : The aim of this study was to investigate the protective effects of hyperoxygenated solution ( HOS ) preconditioning on intestinal ischemia - reperfusion ( IR ) injury in rabbits . - pubmed
MATERIALS AND METHODS : Thirty - two rabbits were randomly divided into four groups as follows : ( 1 ) control group in which sham operation was performed ( Sham group ) ; ( 2 ) sham operation and HOS treatment group ( sham+H group ) ; ( 3 ) ischemia - reperfusion group ( IR group ) ; ( 4 ) ischemia - reperfusion and HOS treatment group ( H group ) . - pubmed
The sequencing of their genomes has revealed that a surprisingly large proportion of genes relevant for human disease have counterparts in the worm and in the fly . - pubmed
We present our experience with a patient in whom a homograft conduit was used to connect the superior vena cava ( SVC ) to the right pulmonary artery ( RPA ) in a functionally univentricular heart where corrective repair was impossible . - pubmed
Characterization of human prostate and breast cancer cell lines for experimental T cell - based immunotherapy . - pubmed
METHODS : To assess the relative contribution of infection and drugs , we compared the expression of marker genes corresponding to mitochondrial function , adipocyte differentiation and metabolism , and adipokines in subcutaneous adipose tissue from healthy controls , untreated HIV-1 - infected patients , and HIV-1 - infected patients treated with HAART with or without HALS . - pubmed
CONCLUSIONS : Disturbances in adipose tissue gene expression are already present in untreated HIV-1 - infected patients , thus indicating a role of HIV-1 infection itself in eliciting adipose tissue alterations that are worsened by HAART , which ultimately leads to HALS . - pubmed
Of the 3,400 hypertensive patients included in the study , 315 ( 9.3 % ) patients ( mean age : 66.9+/-10.4 years ; males : 43.5 % ) were prescribed diuretics . - pubmed
In mosaic arthroplasty defects of live sheep , bleeding occurred beneath part of the hydrogel carrier , and the gel was cleared after 1 month in vivo . - pubmed
Louis encephalitis virus , West Nile virus , and consensus sequences for tick - borne encephalitis complex groups : Russian Spring - Summer encephalitis and Central European encephalitis viruses . - pubmed
Similarly , in portal hypertensive rats portal systemic shunting measured by intrasplenic injections of radiolabelled cobalt microspheres ( 37.1 + /- 3.9 % ) was significantly greater ( p & lt ; 0.005 ) than in control animals . - pubmed
Pyridoxine supplementation for the treatment of levetiracetam - induced behavior side effects in children : preliminary results . - pubmed
Here we apply the integrative genomics principles to interrogate relationships between structural features and gene expression patterns of disease - linked SNPs , microRNAs and mRNAs of protein - coding genes in association to phenotypes of 15 major human disorders , namely bipolar disease ( BD ) ; rheumatoid arthritis ( RA ) ; coronary artery disease ( CAD ) ; Crohn ' s disease ( CD ) ; type 1 diabetes ( T1D ) ; type 2 diabetes ( T2D ) ; hypertension ( HT ) ; ankylosing spondylitis ( AS ) ; Graves ' disease ( autoimmune thyroid disease ; AITD ) ; multiple sclerosis ( MS ) ; breast cancer ( BC ) ; prostate cancer ( PC ) ; systemic lupus erythematosus ( SLE ) ; vitiligo - associated multiple autoimmune disease ( VIT ) ; and ulcerative colitis ( UC ) . - pubmed
Our analysis reveals a systematic primary sequence homology / complementarity - driven pattern of associations between disease - linked SNPs , microRNAs and protein - coding mRNAs defined here as a human disease phenocode . - pubmed
This review is intended as a first step to develop an instrument for identifying patients at high risk for CPSP , to optimize clinical pain management . - pubmed
This report stresses the importance of early , minimally interrupted , chest compression CPR in children who suffer sudden cardiac arrest in the out - of - hospital setting where defibrillation could be delayed . - pubmed
A series of images in localized fibrinolytic treatment for a patient with acute superior mesenteric artery thromboembolism . - pubmed
Antitumor effect of pretreatment for colon cancer cells with hyperthermia plus geranylgeranylacetone in experimental metastasis models and a subcutaneous tumor model of colon cancer in mice . - pubmed
For in vivo study , colon26 cells were injected via the tail vein or into a subcutaneous area of mice and the numbers of lung metastatic nodules or the volumes of subcutaneous tumors were assessed . - pubmed
The Safe Implementation of Thrombolysis in Stroke Monitoring Study ( SITS - MOST ) of 6,483 patients treated with intravenous alteplase within 3 h after stroke onset showed that this treatment was as safe and as effective in clinical practice as in randomized controlled trials . - pubmed
After SITS - MOST , the registry is generating new information on outcome predictors , treatments in patients in later time windows , patients with hyperdense middle cerebral artery signs , and several publications are in preparation . - pubmed
[ Galavit - induced change of immunologic parameters in patients with non - small lung cancer ] . - pubmed
Our results show that similar to other molecular chaperones , both human and parasite TCTPs can bind to a variety of denatured proteins and protect them from the harmful effects of thermal shock . - pubmed
ATL - like marked atypical lymphocytosis associated with drug - induced hypersensitivity syndrome and human herpesvirus-6 reactivation . - pubmed
BACKGROUND : It has been reported that manipulative therapy directed at the cervical and thoracic spine may improve outcomes in patients with shoulder pain . - pubmed
To date , limited data are available to help physical therapists determine which patients with shoulder pain may experience changes in pain and disability following the application of these interventions . - pubmed
OBJECTIVE : The purpose of this study was to identify prognostic factors from the history and physical examination in individuals with shoulder pain who are likely to experience rapid improvement in pain and disability following cervical and thoracic spine manipulation . - pubmed
influenzae strains and all 110 ( 100 % ) H. - pubmed
influenzae strains were H. - pubmed
Screening of genes involved in chromosome segregation during meiosis I : toward the identification of genes responsible for infertility in humans . - pubmed
To identify candidate genes responsible for infertility in humans , we performed gene expression profiling of mouse spermatogenic cells undergoing meiotic prophase I. - pubmed
These 726 candidates for human infertility genes might serve as a useful resource for next - generation sequencing combined with exon capture by microarray . - pubmed
RESULT(S ): Cetrorelix inhibited ovulation in mice , as shown by an increase in number of tertiary follicles concomitant with a significant inhibition of follicle rupture and corpora lutea formation . - pubmed
A semi - structured questionnaire was administered to consecutive consenting caregivers of HIV - infected children aged & gt;=6 years attending the Paediatric Infectious Disease Clinic of the University College Hospital , Ibadan , between November 2008 and October 2009 . - pubmed
METHODS : Sheep ( n = 15 ) underwent intracoronary sphere injection to create chronic ischemic heart failure . - pubmed
[ Occurrence of struma ovarii among women operated for ovarian teratoma ] . - pubmed
Authors reviewed the records of 94 patients operated for ovarian teratoma in their department between 1986 and 2002 , of which 3 patients proved to have struma ovarii . - pubmed
They found that the 3 patients had highly variable clinical symptoms and morphological characteristics including tumor size , pain as main symptom , and the presence or absence of ascites and hormonal activity . - pubmed
Al - treated rats showed lower body weight , lower serum pH , higher accumulation of Al , in addition to disordered metabolism of calcium and phosphorus compared with control rats . - pubmed
These findings suggest that long - term Al exposure in an acidic condition inhibits bone formation and induces bone loss in young growing animals . - pubmed
Thus , in vivo experiments on trabecular bone healing and osteoporosis research for application in humans can be conducted in ovine , bovine , or porcine species . - pubmed
Mineralocorticoid receptor antagonists ( MRAs ) have been effective in reducing total mortality in patients with heart failure ( HF ) and a reduced left ventricular ejection fraction . - pubmed
Role of etravirine in the management of treatment - experienced patients with human immunodeficiency virus type 1 . - pubmed
Its safety profile is comparable to placebo with the exception of rash , which has been mild and self - limited in the great majority of patients . - pubmed
METHODS : We analyzed MUPs recorded from biceps brachii muscle , including 209 associated with ALS ( 12 patients ) and 127 with SMA ( 5 patients ) . - pubmed
Analysis of variola and vaccinia virus neutralization assays for smallpox vaccines . - pubmed
Possible smallpox reemergence drives research for third - generation vaccines that effectively neutralize variola virus . - pubmed
A comparison of neutralization assays using different substrates , variola and vaccinia ( Dryvax and modified vaccinia Ankara [ MVA ] ) , showed significantly different 90 % neutralization titers ; Dryvax underestimated while MVA overestimated variola neutralization . - pubmed
Thirty years after the discovery of the human immunodeficiency virus ( HIV ) as the cause of acquired immunodeficiency syndrome ( AIDS ) , no effective vaccines are available and there is no cure for the disease . - pubmed
The ACI rat model of 17beta - estradiol ( E2)-induced mammary cancer has gained wide use in the study of breast cancer etiology , prevention , and genetics . - pubmed
The method is simple and fast for the preliminary pharmacokinetic study of cefuroxime lysine in liver - injured rats . - pubmed
The effect of semelil ( angipars ) on bone resorption and bone formation markers in type 2 diabetic patients . - pubmed
METHODS : In this randomized , double- blind clinical trial , 61 diabetic patients were included . - pubmed
A QTL analysis was conducted with disease severity and infection type data obtained by controlled inoculation of the population with each of two previously characterized pathotypes of Puccinia graminis subsp . - pubmed
Ethanol extract of Peperomia pellucida ( Piperaceae ) promotes fracture healing by an anabolic effect on osteoblasts . - pubmed
MATERIALS AND METHODS : Ethanol extract of Peperomia pellucida was administered at 100 and 200mg / kg doses orally to adult female Sprague - Dawley rats having a drill hole injury ( 0.8 mm ) in the femur diaphysis . - pubmed
RESULTS : Ethanol extract from Peperomia Pellucida ( L. ) dose - dependently induced bone regeneration at the fracture site . - pubmed
CONCLUSION : Ethanolic extract of P. pellucid ( L. ) accelerates fracture repair in rats via stimulatory effects on osteoblast differentiation and mineralization , thereby justifying its traditional use . - pubmed
The cancers in these mice are moderately differentiated invasive mucinous adenocarcinomas of the proximal colon that develop by 50 days of age . - pubmed
In vivo studies were carried out for the promising formulation on eyes of albino rabbits by inducing bacterial keratitis . - pubmed
We review demographic trends shaping the difficulties in providing care to incarcerated people with HIV and recommend the Centers for AIDS Research Collaboration on HIV in Corrections as a model of interdisciplinary collaboration in addressing those difficulties . - pubmed
Induction of apoptosis by grape seed extract ( Vitis vinifera ) in oral squamous cell carcinoma . - pubmed
This study is the first to investigate the cytotoxic effects and the mechanism of cell death induced by grape seed extract ( GSE ) in oral squamous cell carcinoma ( KB cells ) . - pubmed
METHODS : This was a substudy of a randomized single - blinded clinical trial reported earlier on critically ill patients with clinical hypovolemia after cardiac or major vascular surgery . - pubmed
CONCLUSIONS : An increase in SvO2 & gt;=2 % , irrespective of a relatively high baseline value , can thus be used as a monitor of fluid responsiveness in clinically hypovolemic patients after cardiac or major vascular surgery , particularly in those with systolic cardiac dysfunction . - pubmed
We included 43 patients with sporadic FTLD - TDP , type A , B , or C , from 269 consecutively autopsied patients with TDP-43 proteinopathy . - pubmed
Patients were categorized as having FTLD without ALS , FTLD - ALS ( onset of FTLD symptoms / signs preceded those of ALS ) , or ALS - FTLD ( onset of ALS symptoms / signs preceded those of FTLD ) . - pubmed
All the patients with type A or C FTLD - TDP were included in the FTLD without ALS group , and all those with type B pathological changes were in the FTLD - ALS or the ALS - FTLD group . - pubmed
An evaluation of the safety and efficacy of cariprazine in patients with acute exacerbation of schizophrenia : a phase II , randomized clinical trial . - pubmed
This study ( NCT00694707 ) evaluated the efficacy and safety of cariprazine in patients with acute exacerbation of schizophrenia . - pubmed
CONCLUSION : The results of this study support the efficacy and safety of cariprazine in patients with acute exacerbation of schizophrenia . - pubmed
METHODS : Rats with visceral hypersensitivity were generated using neonatal colon irritation during postnatal days 8 - 15 as described previously . - pubmed
Abdominal withdrawal reflex ( AWR ) scores and pain thresholds were also detected in adult rats . - pubmed
The pain threshold in rats with visceral hypersensitivity significantly decreased compared to control rats ( P & lt ; 0.05 ) . - pubmed
Many hyperthyroid cats develop azotaemic chronic kidney disease ( aCKD ) following treatment , which has led to the hypothesis that hyperthyroidism might be detrimental to renal function . - pubmed
Therefore , tubular hypoxia may not be a mechanism for renal damage in hyperthyroid cats . - pubmed
The final valve position was adequate in 91.2 % of the Case patients and in 97 % of the Control patients , with no cases of valve migration or coronary obstruction . - pubmed
METHOD : Forty - women with primary breast cancer undergoing a modified radical mastectomy were randomized to receive postoperative analgesia with flurbiprofen axetil combined with fentanyl or fentanyl alone . - pubmed
However , it is now becoming increasingly clear that MVs are also stable in the circulation of cancer patients , where they can mediate long - range effects and contribute to the formation of the pre - metastatic niche , an essential step in metastasis ( Skog et al . - pubmed
, Nat Med 18:1835 - 1840 , 2012 ) , point to critically important roles for MVs in human cancer progression that can potentially be exploited to develop new targeted approaches for treating this disease . - pubmed
MATERIAL AND METHODS : Examinations of 20 MS patients ( 10 women , 10 men ) were reviewed retrospectively . - pubmed
CONCLUSION : 3D FLAIR sequences can improve the detection of brain lesions in patients with MS and are even more sensitive in depicting lesions in cortical and infratentorial locations than current dual - echo sequences . - pubmed
BACKGROUND : In our Institute , most of the patients treated for hand injuries were industrial workers with poor compliance . - pubmed
A total of 100 patients and 139 digits with zone II flexor tendon injuries were studied . - pubmed
Treatment of hypercholesterolemia : screening of Solanum macrocarpon Linn ( Solanaceae ) as a medicinal plant in Benin . - pubmed
The present study is conducted to evaluate the lipid lowering activity of leaves and fruits of Solanum macrocarpon , a vegetable , on Wistar rats experimentally rendered hypercholesterolemic by Triton X-100 . - pubmed
for 7 days to rats at doses of 400 and 800 mg / kg of body weight . - pubmed
Hepatic disorders due to the Triton have been corrected by S. - pubmed
CONCLUSIONS : This vegetable effectively suppresses experimental hypercholesterolemia in Wistar rats , suggesting a protective role in cardiovascular diseases . - pubmed
BACKGROUND : Combined heart - liver transplantation ( CHLT ) is an uncommonly performed procedure for patients with coexisting cardiac and liver disease . - pubmed
CONCLUSION : Combined heart - liver transplantation is a life - saving operation that is performed with relatively low mortality and can be successfully performed in select patients with congenital or acquired cardiac disease . - pubmed
A 37 - year - old woman was referred to our institution for further management of a mass lesion located in the thoracic cavity . - pubmed
The patient had complained of left - sided flank pain for a year and experienced dyspnea for one month . - pubmed
The patient underwent adjuvant chemotherapy and has been doing well without any evidence of recurrence for 14 months . - pubmed
We report draft genome sequence of Ochrobactrum intermedium strain 229E concurrent with Helicobacter pylori in urease positive gastric biopsy of non - ulcer dyspeptic individual from Southern part of India . - pubmed
intermedium 299E strain revealed functional similarities with virulence related gene clusters present in H. - pubmed
[ Inhibitory effects of Kukoamine B on the inflammatory response of small intestine in lipopolysaccharide - induced septic mice and its potential mechanisms ] . - pubmed
OBJECTIVE : To study the role of Kukoamine B ( KB ) in inhibiting the inflammatory response of small intestine in septic mice and its molecular mechanisms . - pubmed
MATERIAL AND METHODS : We performed a cross - sectional study among patients with liver disease , inflammatory bowel disease , cancer or pancreatitis . - pubmed
METHODS : Case studies on two patients with LAHS were reviewed , details on their presentation , work up and management were extracted . - pubmed
Additionally the review of the literature reveals that there are 15 case reports and 5 case series that report 25 children with LAHS - AI , 9 case reports and 6 case series report 26 children of LAHS associated with viral infections ( LAHS - VI ) . - pubmed
All patients with LAHS - AI had a protracted course and needed prolonged treatment with immune - suppressive therapy while patients with LAHS - VI resolved spontaneously or needed short - term immune - modulating therapy . - pubmed
METHODS : We compared intestinal microbiota of patients with IF ( n = 23 ) with healthy controls ( n = 58 ) using culture - independent phylogenetic microarray analysis . - pubmed
METHODS : One hundred twenty - eight patients were treated with PVP for osteoporotic vertebral compression fracture ( VCF ) where 46 patients underwent PVP with JN needle and 82 patients with BVF . - pubmed
Effects of alkylation and immunopotentiation against Ehrlich ascites murine carcinoma in vivo using novel tetra - O - acetate haloacetamido carbohydrate analogs . - pubmed
In vitro , IC50 values of all four Tet - OAHCs were determined against Ehrlich ascites murine carcinoma , as well as two leukemias ( U937 human monocytic leukemia and L1210 murine lymphoid leukemia ) to assess their cytotoxicity in multiple neoplastic cell lines . - pubmed
3 ) The analogs demonstrate marked in vivo activity in both B6D2F1 and CD2F1 mice challenged with a lethal dose of Ehrlich ascites carcinoma , and frequently produce long term survival at 60 days , which is not observed in simple halo derivatives or two currently approved antineoplastic agents ( daunorubicin and mechlorethamine ) . - pubmed
Pre - clinical neurobiological models of addiction etiology including both the allostatic model and incentive sensitization theory suggest that alcohol consumption among alcohol - dependent ( AD ) individuals will be dissociated from hedonic reward as positive reinforcement mechanisms wane in later stage dependence . - pubmed
Dual grading were performed with adjudication of admission fluorescein images from a large cohort of children with cerebral malaria . - pubmed
Documentation of renal glomerular and tubular impairment and glomerular hyperfiltration in multitransfused patients with beta thalassemia . - pubmed
We aimed to assess the frequency and predictors of glomerular and tubular defects , renal impairment , and hyperfiltration in 96 adult patients with beta thalassemia intermedia and major . - pubmed
Renal glomerular and / or tubular defects were observed in about 68.8 % of all patients . - pubmed
Forty percent of patients had glomerular hyperfiltration . - pubmed
Renal tubular and glomerular damage is frequent in adult patients with thalassemia intermedia and major . - pubmed
This retrospective study concerns 53 patients aged 16 to 55 years , hospitalized for hemorrhage stroke in the neurological department of Fann Teaching Hospital during 2010 . - pubmed
Hypertension was found in 62 % of the patients , and 11 % had a history of stroke . - pubmed
During the acute phase of hemorrhage , glycemic levels were high among one third of the patients . - pubmed
Curative intravenous quinine treatment was used in 154/155 patients with severe malaria and atovaquone / proguanil in 74 % of patients with uncomplicated malaria . - pubmed
Hospital mortality was 5.2 % ( 8 patients ) , all in the severe malaria group . - pubmed
METHODS : We reviewed medical records of children with diabetes diagnosed before 12months of age . - pubmed
RESULTS : 12 patients were diagnosed with diabetes before 6months of age ( PNDM=6 ; TNDM=6 ) , and 11 patients between 6 and 12months ( all with permanent diabetes ) . - pubmed
CONCLUSIONS : Investigating the underlying genetic basis of diabetes in children with onset before 1year is useful for choosing the most efficient treatment , the basis of Personalized Medicine . - pubmed
Patients with chronic insomnia have selective impairments in memory that are modulated by cortisol . - pubmed
The participants in this study were selected from the clinical setting and included 21 patients with chronic insomnia disorder ( CID ) , 25 patients with insomnia and comorbid depressive disorder ( CDD ) , and 20 control participants without insomnia . - pubmed
Compared to the controls , the CID patients made significantly more errors in spatial working and object recognition memory ( p & lt ; .05 ) , whereas the CDD patients performed poorly in all the assessed memory types ( p & lt ; .05 ) . - pubmed
After controlling for confounding variables , the partial correlation analysis revealed that the levels of cortisol positively correlated with the errors in object working memory ( r = .534 , p = .033 ) and negatively correlated with the errors in object recognition memory ( r = -.659 , p = .006 ) in the CID patients . - pubmed
The results suggest that the CID patients had selective memory impairment , which may be mediated by increased cortisol levels . - pubmed
CASE REPORT : A 35 - year - old woman presented with waist pain for over 1 month . - pubmed
Retinal sensitivity after selective retina therapy ( SRT ) on patients with central serous chorioretinopathy . - pubmed
PURPOSE : To assess retinal sensitivity after selective retina therapy ( SRT ) in patients with central serous chorioretinopathy ( CSCR ) . - pubmed
METHODS : Seventeen eyes of 17 patients with CSCR lasting longer than 3 months were treated with SRT ( wavelength 527 nm Nd : YLF laser , 50 - 150 muJ / pulse , spot diameter 200 mum ) . - pubmed
In seven of them , a paramedian ITSC transcollicular approach was used to resect intrinsic mid - brain lesions , and in the other nine patients , an intermediate or lateral ITSC infra - trochlear approach was used for ponto - mesencephalic lesions . - pubmed
In seven patients with mid - brain lesions , the preoperative ocular symptoms improved in three of them , and the neurological deficits - other than ocular symptoms improved - in five of them . - pubmed
In nine patients with a ponto - mesencephalic lesion , the preoperative ocular symptoms improved in four of nine patients , and the neurological deficits other than ocular symptoms improved in five of them , while one patient exhibited venous infarction in a cerebellar hemisphere that caused neurological deterioration . - pubmed
Additionally , the treatment was further analyzed with respect to models of AD and PD in mice . - pubmed
Auditory hallucinations constitute an important symptom component in 70 - 80 % of schizophrenia patients . - pubmed
In this study , we describe the development of an auditory signal detection task using a carefully chosen set of English words that could be tested successfully in schizophrenia patients coming from varying linguistic , cultural and social backgrounds . - pubmed
Schizophrenia patients with significant auditory hallucinations ( N=15 ) and healthy controls ( N=15 ) performed the auditory signal detection task wherein they were instructed to differentiate between a 5 - s burst of plain white noise and voiced - noise . - pubmed
Impaired reproduction in Japanese Black cattle under cold environmental conditions . - pubmed
Structural lesions were seen in 74 patients ( 67 % ) and inflammatory lesions in 88 ( 79 % ) . - pubmed
CONCLUSION : This prospective observational cohort study in daily clinical practice shows a high prevalence of structural and inflammatory US lesions in AS patients with longstanding and active disease . - pubmed
METHODS : Clinical trial , double - blind , crossover , in which we evaluated healthy adolescent athletes with allergic rhinitis , using experimental and placebo ENDs , submitted to a maximum cardio - respiratory test in randomized order . - pubmed
RESULTS : 65 adolescents participated in the study , 30 of whom had allergic rhinitis . - pubmed
Reperfusion Options for ST Elevation Myocardial Infarction Patients with Expected Delays to Percutaneous Coronary Intervention . - pubmed
METHODS : Whole blood gene expression profiles , performed using the Illumina HT-12v4 Human Expression Beadchip , were compared between ( i ) individuals with obesity ( O ) or lean ( L ) individuals ( n=21 each ) , ( ii ) individuals with ( M ) or without ( H ) Metabolic Syndrome ( n=11 each ) matched on age and gender . - pubmed
In large human cohort studies , bilateral hippocampal structures are frequently identified and measured to gain insight into human behaviour or genomic variability in neuropsychiatric disorders of interest . - pubmed
CLINICAL REPORT : We have presented the case of a patient who developed a delayed pruritic , and erythematous maculopapular skin exanthema after the intake of amlodipine . - pubmed
ETHNOPHARMACOLOGICAL RELEVANCE : Cordyceps sinensis is a traditional Chinese medicine and has been used as adjuvant treatments for cancer and it has been also demonstrated to be effective in cancer patients . - pubmed
AIM OF THE STUDY : The objective of the present study is to investigate the anti - metastasis effects of water extracts of Cordyceps sinensis ( WECS ) in breast cancer and the potential mechanisms . - pubmed
The in vivo anti - metastatic activity of intraperitoneally administered WECS and its effect on animal survival were measured in a mouse breast cancer metastasis model . - pubmed
In animal studies , 50mg / kg WECS significantly reduced the number of metastatic lung nodules and the weight of lung , without affecting body weight of mice . - pubmed
Furthermore , WECS increased the survival rate of 4T1 tumor bearing mice in a dose dependent manner , and at high dose , WECS ( 50mg / kg ) significantly increased the life span of the mice compared to untreated control group . - pubmed
Staphylococcus aureus is the major cause of foodborne diseases worldwide . - pubmed
One isolate was obtained from a pet ( dog ) , one from an exotic animal ( a circus elephant ) , and four human isolates were obtained during a severe food poisoning outbreak that occurred in Sicily in 2015 . - pubmed
We also determined lethal toxicity of the venom ( LD50 : 9.17 mug per mouse ) , and established the assay for the determination of an anti - lethal titer of antivenom in mice . - pubmed
BACKGROUND : While it is known that perfluoroalkyl substances ( PFASs ) induce liver toxicity in experimental studies , the evidence of an association in humans is inconsistent . - pubmed
METHODS : A total of 69 rectal cancer patients from a single referral surgical unit who had a loop ileostomy during low anterior resection of the rectum were included in this study . - pubmed
Atorvastatin - Associated Macroglossia in a Cardioembolic Stroke Patient . - pubmed
A single session of visual feedback improves range of motion in patients with chronic idiopathic neck pain : A randomized and controlled study . - pubmed
OBJECTIVE : The clinical challenge in blunt nasal trauma in children , is to identify cases requiring specialized care among frequently encountered banalities , whilst trying to minimize the exposure to diagnostic procedures . - pubmed
METHODS : This retrospective cohort study includes children up to 16 years presenting at the emergency department with blunt nasal trauma of our tertiary reference center . - pubmed
Additionally , they did not evidence any accurate cytotoxicity when incubated with healthy human foreskin fibroblast ( BJH ) cells for doses as high as 50 mug mL-1 and contact time as long as 48 h , highlighting the ability of the prepared particles to be used as efficient down - converter light sources for cell labelling . - pubmed
Broiler chicken meat is considered as the main source of foodborne Campylobacter infection . - pubmed
Campylobacter jejuni multilocus sequence type ST-5 has been previously identified as predominant among Latvian and Lithuanian broiler chicken meat products and is often isolated from Lithuanian patients with Campylobacter enteric infection . - pubmed
RESULTS : Twenty - two GFFs ( unilateral n = 8 ; bilateral n = 7 ) were performed in 15 patients ( nine women and six men ; anal squamous cell carcinoma n = 8 ; rectal adenocarcinoma n = 7 ; mean age 65.5 + 8.2 years ) with a mean follow - up time of 1 year . - pubmed
Methods : First , we transplanted autologous nucleus pulposus into dorsal root ganglions to establish chronic radiculitis in rats . - pubmed
Results : Chronic radiculitis was established in rats . - pubmed
Acute stroke care should be reorganized by making use of the examples of workflow interventions described in this review to ensure the best medical care for stroke patients . - pubmed
Prominent for its resilient mutagenicity and toxicity , DBF poses a major challenge to human health . - pubmed
In the present study , a new strain of Pseudomonas aeruginosa , FA - HZ1 , with high DBF - degrading activity was isolated and identified . - pubmed
A total of 1459 proteins were identified in strain FA - HZ1 , of which 100 were up - regulated and 104 were down - regulated . - pubmed
Case presentation An 11 - year - old boy presented with severe hypertension ( HTN ) with cardiac target organ damage . - pubmed
Signs and symptoms attributable to ectopic hormones should be investigated in PCC patients . - pubmed
This indicates that premenopausal women may experience protection against deleterious effects of acute hyperglycemia , regardless of menstrual cycle phase . - pubmed
However , research in healthy premenopausal women is lacking and the impact of menstrual phase [ early follicular ( EF ; low estrogen ) and late follicular ( LF ; high estrogen ) ] on vulnerability to acute hyperglycemia - induced changes in arterial stiffness is unknown . - pubmed
These results suggest that premenopausal women may experience protection from acute hyperglycemia - induced increases in arterial stiffness . - pubmed
Here , we briefly describe the progress made towards a vaccine against Plasmodium falciparum , the most pathogenic of the malaria parasite species to infect humans . - pubmed
Single - agent ibrutinib in RESONATE-2 and RESONATE versus treatments in the real - world PHEDRA databases for patients with chronic lymphocytic leukemia . - pubmed
After analyzing treatment patterns in chronic lymphocytic leukemia ( CLL ) ( objective 1 ) , we investigated the relative effectiveness of ibrutinib versus other commonly used treatments ( objective 2 ) in patients with treatment - naive and relapsed / refractory CLL , comparing patient - level data from two randomized registration trials with two real - world databases . - pubmed
Grade > = 3 adverse drug reactions ( ADRs ) were reported in 61.7 % of the patients . - pubmed
Carcinoma of the breast ( 21.3 % ) , lung ( 12.9 % ) , and gastrointestinal tract ( GIT ) ( 35.8 % ) accounted for the majority of the patients , and 44.7 % of the patients had metastatic disease . - pubmed
RESULTS : Anemia was observed in 49.7 % of patients with cancer and in 11.9 % of healthy controls ( p < 0.001 ) . - pubmed
Having metastatic disease , and having nutritional deficiencies as iron , B12 , and folate were evaluated as possible risk factors for anemia in patients with newly diagnosed cancer , whereas cancer with GIT localization and previous history of tumor surgery were not . - pubmed
Quercetin - Mediated Apoptosis and Cellular Senescence in Human Colon Cancer . - pubmed
BACKGROUND : Quercetin is a flavonol from the flavonoid group of polyphenols which positively affects human health due to its anti - cancer , anti - inflammatory , anti - microbial and cardioprotective effects . - pubmed
Further , MycoAuNPs showed potential growth of tumor in tumor - bearing mice models . - pubmed
Further attention placed on potential sex differences in epilepsies , comorbidities , and drug effects will enhance therapeutic options and efficacy for all patients with epilepsy . - pubmed
In this review , we discuss sex differences in types of epilepsies , associated comorbidities , pathophysiological mechanisms , and antiepileptic drug efficacy in both clinical patient populations and preclinical animal models . - pubmed
The lifestyle and lowered daily activity of elderly adults , along with the deficit of motor and cognitive brain functions , might lead to the developed ambidexterity , i.e. - pubmed
We reviewed pathological findings and clinical breast MRI examinations of 169 patients with invasive BC who were evaluated at the Hotel - Dieu de France Hospital in 2009 - 2015 . - pubmed
Myositis induced by durvalumab in a patient with non - small cell lung cancer : A case report . - pubmed
A 60 - year - old man with stage IIIA lung adenocarcinoma was treated with durvalumab after concurrent chemoradiation therapy . - pubmed
Centruroides margaritatus scorpion stings are common in Colombia . - pubmed
Vision - related quality of life in patients with a history of congenital glaucoma . - pubmed
PURPOSE : To assess the vision - related quality of life in adult patients with a history of primary congenital glaucoma . - pubmed
METHODS : In a cross - sectional hospital - based study eligible patients with a history of primary congenital glaucoma aged more than 18 were recruited in the study . - pubmed
Patients with secondary glaucoma and monocular patients were excluded . - pubmed
RESULTS : A total of 23 congenital glaucoma patients have enrolled in the study . - pubmed
OBJECTIVES : This study aims to investigate the effect of radial extracorporeal shock wave therapy ( rESWT ) treatment in the prevention of epidural fibrosis after laminectomy in rats . - pubmed
CONCLUSION : The rESWT application immediately after surgery is effective in preventing epidural fibrosis after laminectomy in rats . - pubmed
Wastewater - based surveillance of the severe acute respiratory syndrome coronavirus 2 ( SARS - CoV-2 ) is used to monitor the population - level prevalence of the COVID-19 disease . - pubmed
The methods and criteria for testing for synergy were compared with use of 22 strains of Klebsiella pneumoniae and a combination of cephalothin and gentamicin . - pubmed
The indications , investigations and techniques for treating patients with chyluria are presented . - pubmed
A case of thymic carcinosarcoma associated with a spindle cell thymoma in a 71 - year - old woman is reported . - pubmed
The following analyses , which examined whether the timing of the first breast milk substitute to which the infant was exposed differed between diabetic and control subjects , were conducted for exposure to any breast milk substitute and to breast milk substitutes that were cow 's milk based . - pubmed
In whites , age at exposure to any breast milk substitutes and cow 's milk - based substitutes were similar between diabetic and control subjects . - pubmed
In blacks , the first exposure to breast milk substitutes occurred significantly earlier for any substitute ( 5.1 vs. 11.9 wk , P = 0.02 ) and marginally earlier for cow 's milk - based substitutes ( 3.9 vs. 8.5 wk , P = 0.07 ) in diabetic subjects compared with control subjects . - pubmed
Effects of exercise test on plasma markers of an activation of coagulation and/or fibrinolysis in patients with symptomatic or silent myocardial ischemia . - pubmed
Symptoms and scintigrams allowed to define three groups of patients : those showing no ischemia ( n = 79 ) and those with symptomatic ( n = 8) or silent myocardial ischemia ( n = 13 ) . - pubmed
On the other hand , the F1 + 2 levels were slightly albeit significantly higher in the patients without ischemia than in the patients with symptomatic or silent ischemia . - pubmed
When P19 mouse embryonal carcinoma cells are grown in a serum - free N2 medium on surfaces of tissue culture plastic , they die within two days . - pubmed
[ Diagnosis and therapeutic tactics in destructive cholecystitis in middle - aged and elderly patients ] . - pubmed
Differential tumor regression in patients with bilobar hepatic metastases and dual arterial supply : evidence supporting the advantage of intra - arterial over intravenous route of drug delivery . - pubmed
Two patients with bilobar liver metastases were characterized by dual arterial blood supply to the liver . - pubmed
Treatment of both patients by the administration of chemotherapy , selectively via the arterial branches supplying the respective hepatic lobes bearing the metastases , resulted in differential tumor regression / progression . - pubmed
When 6 - 7 months old , MSG - treated rats presented reduced body , adrenal and pituitary weight , obesity , atrophy of the optic nerve and damage of the arcuate nuclei ( ARN ) of the hypothalamus . - pubmed
These results suggest that the ARN may be involved in the regulation of the pituitary - adrenal axis , although the abnormalities observed in the MSG syndrome partially differ from those in rats with hippocampal damage , previously studied in our laboratory . - pubmed
A 30 week gestation infant developed necrotising enterocolitis associated with Clostridium perfringens septicaemia at 3 weeks of age . - pubmed
In a 59 - year - old patient with Crohn ' s disease , tricuspid valve endocarditis caused by candida albicans was observed . - pubmed
We have applied this technique of profound hypothermia and circulatory arrest in three other adult patients in whom conventional techniques would not allow safe and adequate complete repair of acquired intra - cardiac defects . - pubmed
The second patient underwent valve replacement during a period of circulatory arrest because of extensive calcification of the entire ascending aorta and transverse aortic arch . - pubmed
The third patient was a 54 - year - old female and had a large patent ductus arteriosus with a 3:1 left - to - right shunt as well as significant aortic and mitral valve disease . - pubmed
All three patients recovered uneventfully with no evidence of any significant neurologic defect . - pubmed
Very long chain fatty acid ( VLCFA ) beta - oxidation was compared in homogenates and subcellular fractions of cultured skin fibroblasts from normal individuals and from Zellweger patients who show greatly reduced numbers of peroxisomes in their tissues . - pubmed
Thus the relationship of pseudomyotonia to increasing oxidative activity in the hind limb muscles of dystrophic animals was evident . - pubmed
The second patient experienced conjunctival pruritus after each of several doses of zomepirac before emergency department presentation with acute dyspnea and urticaria . - pubmed
The third patient had been admitted previously with a diagnosis of rule out myocardial infarction , which in retrospect was probably a zomepirac reaction . - pubmed
[ Serum and liquor immunoelectrophoresis in normal subjects and in patients affected by degenerative and spondylosic myelopathies ] . - pubmed
[ The use of aminokrovin in the treatment of children suffering from Botkin ' s disease ] . - pubmed
Besides , antibody to tick - borne encephalitis virus , Powassan virus and both viruses simultaneously was found in patients with progredient forms of tick - borne encephalitis and in subjects with the history of tick attachment . - pubmed
The injury was caused by acid in 57 patients ( 33 % ) . - pubmed
Fifty three patients mostly with alkaline and acid burns were treated with prolonged irrigation with one liter of physiological saline using intravenous delivery system during 1 - 2 hours . - pubmed
Collagen metabolism was studied in patients with viral hepatitis , chronic hepatic disorders as well as under experimental conditions , in rats with carbon tetrachloride - induced hepatic fibrosis . - pubmed
Islet cell transplantation in diabetic dogs : studies of graft function and storage . - pubmed
Islet cell autotransplants rendered such animals metabolically normal apart from persisting impairment of glucose tolerance . - pubmed
[ Individual variation and mechanism of kanamycin ototoxicity in rabbits ( author 's transl ) ] . - pubmed
93 patients who had been irradiated before or after surgery of a hypernephroma were checked up in order to find secondary diseases . - pubmed
Sixteen patients had died , three of them because of therapy effects , six because of tumor recurrences and seven because of other factors . - pubmed
Two patients had local recurrences . - pubmed
Ocular Toxoplasmosis is usually considered a recurrence of a congenital infection , and this fact enhances the importance of prevention in pregnant women in order to avoid transplacental passage of free forms of the parasite Toxoplasma gondii . - pubmed
All of the Tg(MHu2 M ) mice developed neurologic disease approximately 200 days after inoculation with brain homogenates from three patients dying of Creutzfeldt - Jakob disease ( CJD ) . - pubmed
About 10 % of Tg(HuPrP ) mice expressing HuPrP and non - Tg mice developed neurologic disease & gt ; 500 days after inoculation with CJD prions . - pubmed
Diagnosis , prevention , and treatment of Hu prion diseases should be facilitated by Tg(MHu2 M ) mice . - pubmed
Although control of any degree of hypertension with any antihypertensive drug will slow the progression of renal failure from any cause , captopril , an angiotensin - converting enzyme ( ACE ) inhibitor , has been shown to slow progressive renal failure in patients with insulin - dependent diabetes mellitus to a greater degree than that expected from only its antihypertensive effect . - pubmed
An analysis of results of 758 IVF cases provides preliminary evidence to show that there is a close association between human in vitro fertilization rate and subsequent embryo viability following replacement . - pubmed
In contrast , SD hamsters that were given daily injections of the EAA agonist , N - methyl - D , L - aspartate ( NMA ; 50 mg / kg body weight , s.c . ) - pubmed
BACKGROUND : Uncontrolled increase in intracranial pressure is the most significant cause of mortality in patients with severe traumatic brain lesions , and the efficacy of common non - surgical treatments has been questioned . - pubmed
METHODS : In a porcine model of intracranial hypertension induced with two epidural balloons to a level of 26 - 28 mmHg , 18 animals were randomized into three groups receiving 0.1 , 0.3 , and 3.0 mg.kg-1.h-1 indomethacin , respectively , as an infusion during 80 min . - pubmed
This was accompanied by signs of cerebral ischemia when indomethacin was used in a dose that has previously been suggested for the treatment of increased intracranial pressure in patients . - pubmed
Recurrent hypoglycaemia associated with first and second trimester insulin sensitivity in a patient with insulin - dependent diabetes . - pubmed
A 35 - year - old insulin - dependent diabetic woman presented at 8 weeks gestation with multiple severe hypoglycaemic episodes occurring during the day and night without warning . - pubmed
[ The functional activity of the lymphocyte subpopulations in patients with schizophrenia and schizoaffective psychosis ] . - pubmed
The increase of cytotoxic NK activity was seen in patients with schizoaffective psychosis after the treatment while such alterations in schizophrenic patients were absent . - pubmed
To develop an improved treatment schedule for osteoporosis , a study was undertaken in 100 postmenopausal women using a modified ADFR 90 - day cyclical regimen with etidronate . - pubmed
In addition , coinfection either with HPV-6 and -16 or with HPV-6 and -18 was detected in 20 cases ( 33.3 % of HPV DNA - positive cases ) . - pubmed
Although combination chemotherapy regimens may prolong survival for selected patients with metastatic breast cancer , few , if any , are cured . - pubmed
Imaging investigations and other findings observed in a term infant with a multicentric hepatic hemangioendothelioma , admitted to the Intensive Care Unit at the age of 13 days because of non specified feeding difficulties and dyspnoea , are presented . - pubmed
The pattern of fever response to empiric anti - tuberculosis therapy in patients with tuberculosis ( TB ) and human immunodeficiency virus ( HIV ) infection , and the relationship between fever response patterns and anti - TB drug susceptibility profiles of Mycobacterium tuberculosis isolates are rarely described . - pubmed
Drug susceptibility data were available for 22 patients with TB . - pubmed
138 patients with end - stage kidney disease and 118 patients with end - stage liver disease were included in an observational cohort study regarding their quality of life . - pubmed
An initial rhythm of pulseless electrical activity was present in 50.1 % of the patients , ventricular fibrillation / ventricular tachycardia in 34.2 % , and asystole in 15.7 % . - pubmed
METHODS : Two hundred and ninety - nine Type 2 diabetic patients were investigated for smoking habits by unstructured questionnaire , breath CO , and urinary ratio . - pubmed
Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington ' s disease . - pubmed
We examined the degree of oxidative damage to the brain of mice transgenic for the mutation responsible for Huntington ' s disease . - pubmed
Within a multicenter study 56 patients admitted for chest pain ( & lt ; 12 h ) and with a non - diagnostic 12 - lead ECG on admission and a VCG recording were included . - pubmed
Successful cannulation was achieved in six out of 10 patients with haematoma complicating the procedure in two patients . - pubmed
OBJECTIVE : To describe the clinical findings in patients with acute idiopathic blind spot enlargement ( AIBSE ) . - pubmed
METHODS : Medical record review of 27 patients with AIBSE ( without sufficient optic nerve head swelling to cause blind spot enlargement ) seen in 2 academic neuro - ophthalmology units . - pubmed
All patients had enlarged blind spots of variable size and density . - pubmed
Twelve of the 13 patients who underwent fluorescein angiography had optic disc staining and 5 had retinal pigment epithelial lesions with late staining . - pubmed
Six patients experienced recurrence . - pubmed
Unlike patients with multiple evanescent white dot syndrome , recovery of visual field did not occur in patients with AIBSE . - pubmed
Changes in these domains lead to a reduced functional ability of the AD patient which results , inevitably , in an increasing dependency of the patient on their carer . - pubmed
Thus , a compromised quality of life for both the patient with AD and the carer ensues . - pubmed
The abnormality in cholinergic neurotransmission , by contributing to both the cognitive impairment and possibly the behavioural disturbances of AD patients , has attracted particularly intense scientific attention . - pubmed
Evidence for the involvement of a cholinergic dimension to the behavioural changes of AD includes the following : the induction of AD - like behaviours in normal individuals by administration of anticholinergic drugs ; the exaggeration of behavioural disturbances in AD patients by anticholinergic agents ; the correlation of the distribution of cholinergic deficits of AD with regions that are relevant to the observed behaviours , i.e. - pubmed
RESULTS : All patients , including some with very severe airway anomalies , were uneventfully intubated using the regimen we have described . - pubmed
The onset of hypoventilation was recognized in patients and appropriately treated by adjusting the narcotic dose . - pubmed
Coughing occurred only in 5 patients and 37 out of 40 patients had no recall that intubation had occurred . - pubmed
A 92 - year - old woman with mucinous adenocarcinoma of Bartholin gland with metastasis to the right inguinal lymph node was treated with radiation therapy alone . - pubmed
Despite intensive radiation therapy , the tumor was locally recurrent and the patient died 10 months after radiation therapy . - pubmed
UNLABELLED : Malfunction of vascular access is one of the most frequent causes of morbidity and mortality in hemodialysis patients ( HD ) . - pubmed
Early diagnosis makes possible the most frequent vascular access ( VA ) used in HD patients . - pubmed
Using the Transonic HD01 monitor , we studied vascular access in 45 patients in HD older than 65 years , and compared them with 47 patients who were younger than 65 years . - pubmed
Ammonia toxicity as a criterion for the evaluation of larval quality in the prawn Macrobrachium rosenbergii . - pubmed
CRRT is most commonly indicated for hemodynamically unstable patients who have acute renal failure and a narrow margin of tolerance for the rapid fluid shifts associated with traditional dialysis . - pubmed
and the agent of human granulocytic ehrlichiosis in Colorado . - pubmed
Previous work demonstrated that Ixodes spinipalpis ticks maintained an enzootic cycle of Borrelia bissettii and the agent of human granulocytic ehrlichiosis ( aoHGE ) within woodrats ( Neotoma mexicana ) and deer mice ( Peromyscus maniculatus ) in northern Colorado ( USA ) . - pubmed
METHODS : One hundred twenty - three patients from 98 families with a diagnosis of Hallervorden - Spatz syndrome were classified on the basis of clinical assessment as having classic disease ( characterized by early onset with rapid progression ) or atypical disease ( later onset with slow progression ) . - pubmed
Genetic analysis of longitudinal trajectory of clinical mastitis in first - lactation Norwegian cattle . - pubmed
[ Contribution of electron microscopy to the study of human hepatic steatosis ] . - pubmed
METHODS : The authors studied 18 female patients who underwent either transurethral resection ( n = 2 ) or radical cystectomy ( n = 16 ) for high - grade muscle - invasive urothelial carcinoma of the urinary bladder . - pubmed
OBJECTIVE : This histomorphometric study compared the open and prematurely fused side of the coronal suture in subjects with unilateral coronal synostosis ( UCS ) . - pubmed
METHODS : Sutures and parasutural bone were obtained from seven subjects with nonsyndromic UCS during operative correction at 3 to 24 months of age . - pubmed
The primary causes of squamous cell carcinoma of the esophagus are tobacco use and alcohol consumption , whereas the main risk factors for adenocarcinoma of the esophagus are gastroesophageal reflux disease and obesity . - pubmed
The aim of the present study was to compare patient survival , death - censored technique survival and peritonitis - free survival between patients initiating PD after failed renal allografts and those after failed native kidneys . - pubmed
On multivariate analysis , PD patients with failed kidney transplants had comparable patient mortality [ weighted hazards ratio ( HR ) 1.09 , 95 % confidence interval ( CI ) 0.81 - 1.45 , P = 0.582 ] , death - censored technique failure ( adjusted HR 0.91 , 95 % CI 0.75 - 1.10 , P = 0.315 ) and peritonitis - free survival ( adjusted HR 0.92 , 95 % CI 0.72 - 1.16 , P = 0.444 ) with those PD patients who had failed native kidneys . - pubmed
Traumatic internal carotid artery dissection is a serious condition that may cause ischemic stroke in young patients . - pubmed
The CH ( 2 ) Cl ( 2 )/ CH ( 3 ) OH extract of Kalanchoe crenata significantly increased the latency period in seizures induced by PTZ and significantly reduced the duration of seizures induced by the three convulsant agents . - pubmed
The assay has manifold applications in fundamental research for DNA damage and repair , in genotoxicity testing of novel chemicals and pharmaceuticals , environmental biomonitoring , and human population monitoring . - pubmed
We used pulsed - field gel electrophoresis analysis and genotyping to compare clinical isolates of Bordetella pertussis recovered since the early 1990s in Finland and France , 2 countries with similar histories of long - term mass vaccination with whole - cell pertussis vaccines . - pubmed
It has been proposed that schizophrenia results from an environmental insult in genetically predisposed individuals . - pubmed
It outlines how three students , who formed a collegial group , prepared for the experience , completed and documented assigned visits , summarized outcomes , and discussed some implications for ministry with terminally ill comatose patients . - pubmed
Bilateral tibial chronic osteomyelitis due to Pantoea agglomerans in a patient with sickle cell disease . - pubmed
In mammals , QA intoxication is characterized by trembling , shaking , excitation , and convulsion . - pubmed
A total of 185 patients with localized esophageal cancer were included , 89 undergoing multimodal therapy and 96 surgery alone . - pubmed
PURPOSE : This study was designed to evaluate the pharmacologic and biological properties of a paclitaxel - hyaluronan bioconjugate ( ONCOFID - P ) against IGROV-1 and OVCAR-3 human ovarian cancer xenografts following i.p . - pubmed
Female severe combined immunodeficiency mice implanted with ovarian cancer cells underwent treatment with ONCOFID - P or free paclitaxel starting from day 7 or 14 after tumor injection , and survivals were compared . - pubmed
Intraperitoneal treatment of tumor - bearing mice with the bioconjugate revealed that ONCOFID - P exerted a relevant increase in therapeutic activity compared with free drug . - pubmed
Between July 2003 and July 2006 , we treated 60 patients ( 20 men and 40 women , mean age 26 years ) who suffer from palmar hyperhidrosis by endoscopic thoracic sympathectomy ( ETS ) . - pubmed
METHODS : Clinically depressed older adults with MRI - defined SID ( n = 70 ) and depressed elders without SID ( n = 75 ) were compared on neuropsychological performance , depression symptoms , and medical burden . - pubmed
CONCLUSIONS : Although auditory working memory span and nonverbal memory appear to be specifically associated with the ischemic pathology that defines SID , the typical individual with SID is also likely to have a broader profile of neuropsychological deficits than those without SID because they are typically older and have specific depression symptoms that predispose them to compromised neurocognitive performance . - pubmed
Klebsiella oxytoca as a cause of equine abortion -- short communication . - pubmed
Effects of selenium and low levels of lead on mammary tumor development and growth in MMTV - infected female mice . - pubmed
Selenium ( Se ) has been demonstrated in previous studies to inhibit mammary tumorigenesis in C3H mice infected with the murine mammary tumorvirus , MMTV . - pubmed
In the experimental groups , the Pb - exposed mice on the 0.15 ppm Se feed developed signs of chronic Pb toxicity as evidenced by diminished weight gain that persisted up to the age of 10 months , during which period the animals remained tumor - free . - pubmed
In the group of mice on the 0.65 ppm Se feed , the toxic effects of Pb were diminished , as evidenced by the normal weight gains during the first 10 months but with concomitant physiological inactivation of Se , causing 82.6 % of the mice to develop tumors , with the first tumor to appear at the age of 5 months , 7 months earlier than in the Pb - unexposed controls . - pubmed
Direct evidence for the interactions of Pb with Se were obtained by determinations of the two elements in the livers , kidneys , and hair of tumor - free and tumor - bearing mice . - pubmed
However , the exposure of the mice to Pb in the water also altered the levels of Zn , Cu , Fe , and Cr in the organs and tissues , more so in tumor - bearing than tumor - free animals . - pubmed
In Mexico , Nocardia brasiliensis is the main causative agent of mycetoma , producing about 86 % of the cases ; the gold standard for the therapy of mycetoma by N. - pubmed
In the present work , we evaluated the in vivo effect of DA-7867 , an experimental oxazolidinone , on the development of experimental mycetomas by N. - pubmed
As a control we utilized linezolid at 25 mg / kg , a compound active in murine and human infections , three times a day . - pubmed
Since oxazolidinones seem to be active against a wide spectrum of actinobacteria , it is possible they could be used in human cases of mycetoma by other actinomycetales , such as Streptomyces somaliensis , highly prevalent in Sudan , or Actinomadura madurae and A. - pubmed
The molecular mechanism of dexamethasone - mediated effect on the blood - brain tumor barrier permeability in a rat brain tumor model . - pubmed
METHODS : DNA was extracted from peripheral blood leukocytes of 49 euthymic bipolar patients and 27 matched healthy controls . - pubmed
RESULTS : Leukocyte global DNA methylation did not differ between bipolar patients [ 62.3%+/-18.0 ( S.D ) ] and control subjects ( 63.9%+/-14.6 ) , p=0.70 . - pubmed
Bipolar patients ' plasma homocysteine levels ( 11.5 microM+/-4.8 ) did not differ from those of healthy controls ( 11.4+/-2.9 ) , p=0.92 . - pubmed
Risperidone : a review of efficacy studies in adolescents with schizophrenia . - pubmed
To reveal the molecular and genetic mechanism of fertility restoration in Ogura male sterility in Japanese wild radish ( Raphanus sativus var . - pubmed
RESULTS : Forty - two patients with advanced solid tumors , including 16 NSCLC , were treated . - pubmed
Four patients with NSCLC remained on therapy for 9 , 16 , 16 , and 22 cycles . - pubmed
Subsequent elimination of brucellosis in commercial swine resulted in a decrease in B. - pubmed
Currently , swine - associated brucellosis in humans in the United States is predominantly associated with exposure to infected feral swine ( i.e. - pubmed
Hypomethylating agent induction therapy followed by hematopoietic cell transplantation is feasible in patients with myelodysplastic syndromes . - pubmed
[ Engineering and metabolic characteristics of a Clostridium tyrobutyricum strain ] . - pubmed
This study aimed to determine the effectiveness of a depression training program on practitioners ' confidence , perceived barriers , and their likelihood of responding to depression in patients with vision impairment . - pubmed
CONCLUSIONS : This preliminary study found that a brief training program is effective in increasing practitioners ' ability to respond to depression in patients with vision impairment . - pubmed
Recently , we showed that an active mouse CMV ( mCMV ) infection in nonpregnant mice increased endothelial - dependent vasodilation in isolated mesenteric and uterine arteries . - pubmed
Thus CMV infection affects the contribution of NO differently in endothelial - dependent vasodilation in pregnant compared with nonpregnant mice and also in the mesenteric compared with the uterine vascular bed . - pubmed
A patient with multiple synchronous gliomas of distinctly different grades and correlative radiographic findings . - pubmed
We present a patient with bi - hemispheric , noncontiguous , low- and high - grade gliomas proven by biopsy . - pubmed
CASE DESCRIPTION : A 64 - year - old female presented to the hospital with confusion , disorientation and retrograde amnesia after an unwitnessed fall . - pubmed
We found that standard and large - capacity forceps used with standard upper endoscopes produced biopsy samples at least as adequate as those obtained with jumbo forceps and therapeutic endoscopes in patients with BE . - pubmed
injection of BBL into rats induced a dose - dependent paw edema , an effect that occurred via carbohydrate site interaction and was significantly reduced by L - NAME , suggesting an important participation of nitric oxide in the late phase of the edema . - pubmed
RESULTS : We reviewed the literature and provided several practical examples of common cross - sectional imaging findings in patients with pancreatic neoplasms . - pubmed
The authors discuss the usefulness of therapeutic hypothermia for neuroprotection in patients with hypoxic cerebral damage . - pubmed
Recently , the American Heart Association and European Resuscitation Council recommended the use of mild hypothermia ( 32 - 34 degrees C ) in adult patients after ventricular fibrillation . - pubmed
Randomized clinical trials in newborns with hypoxic ischemic encephalopathy confirm improved neurological outcomes and survival at 18 months of age with therapeutic hypothermia . - pubmed
They conclude that mild hypothermia can be regarded as a useful therapy in adult patients after VF cardiac arrest , and in neonates with hypoxic cerebral brain damage . - pubmed
Similar responses were observed after intravenous administration in spontaneously hypertensive rats . - pubmed
MATERIAL AND METHODS : Thirty - five needle biopsies from patients with prostate cancer ( PC ) aged 60 to 75 years were investigated . - pubmed
Salidroside , a phenol glycoside of plant origin , has been documented to possess a broad spectrum of pharmacological properties , including protective effects against neuronal death induced by different insults . - pubmed
To provide further insights into the neuroprotective functions peculiar to salidroside , this study used primary cultured cortical neurons of rats as a cell model to examine whether salidroside was able to prevent against cell damage after exposure to cobalt chloride ( CoCl ( 2 ) ) , a hypoxia - inducing agent . - pubmed
Keratotic lesions on the nipples and areolae of a 62 - year - old man . - pubmed
An in vit ro model utilizing human cervical cells and papillomaviruses ( HPV ) that mimics human cervical cancer has been developed . - pubmed
Acquisition of immortality after HPV-16 transfection was associated with aneuploidy , structural changes of chromosomes 8 , 10 , 17 , 19 , 20 , and 21 , as well as proto - oncogene alterations . - pubmed
RESULTS : One hundred and ninety patients with apparent early - stage EOC undergoing primary surgical staging met criteria for inclusion . - pubmed
No patients with mucinous cancers ( n=29 ) had lymph node metastases . - pubmed
CONCLUSIONS : Complete surgical staging in EOC patients with gross disease confined to the ovaries and pelvis should include bilateral pelvic and paraaortic lymphadenectomy . - pubmed
Even in patients with unilateral lesions , lymph node metastases are commonly bilateral . - pubmed
This information may be helpful in counseling patients presenting for consideration of re - staging after unexpected findings of malignancy . - pubmed
Dengue virus ( DENV ) is the causative agent of the most prevalent arthropod - borne viral disease , thus representing a significant global health burden . - pubmed
A 65 - year - old man with chronic renal failure due to polycystic kidneys and under hemodialysis treatment 3 times a week for 2 years was admitted to our hospital because of anemia . - pubmed
The experimental groups consisted of 20 gingivitis patients and 20 periodontitis patients and the control group had healthy subjects ( 20 samples ) . - pubmed
Patients with periodontal disease were under conventional periodontal treatment . - pubmed
Tumor hypoxia is known to be associated with radio / chemo - resistance and metastasis that eventually lead to cancer progression contributing to poor prognosis in cancer patients . - pubmed
METHODS : Eleven male adults with unilateral midportion Achilles tendinopathy and nine control male adults without tendinopathy participated in the research . - pubmed
RESULTS : We observed maximum paralysis ( & gt;=70 % ) at 2 weeks , and the rate of recovery varied widely ranging from 2 to 5 months , with two patients continuing to exhibit reduced contraction at 24 weeks . - pubmed
[ Effectiveness of a stretching program on anxiety levels of workers in a logistic platform : a randomized controlled study ] . - pubmed
OBJECTIVE : To study the influence of a short programme of stretching exercises on anxiety levels of workers in a Spanish logistic company . - pubmed
The rate of CRS in this cohort of 196 patients was 10.2 % ( n=20 ) , of which 15 % ( n=3 ) developed ARS , although none had symptoms of CRS at the time of surgery ; one had undergone previous sinus surgery . - pubmed
Presenting symptoms of ARS included facial pain , tenderness over the affected sinus , and nasal discharge ; all patients responded to oral antibiotic therapy . - pubmed
A constant turnover of variant - specific amino acid change was observed , particularly within the antigenic epitopes A , C and E. In conclusion , this study has characterized the NoV strains in circulation in Singapore between 2004 and 2011 . - pubmed
Clinical outcome post - progression to first - line triplet chemotherapy ( CT ) plus bevacizumab ( FIr - B / FOx ) was evaluated in metastatic colorectal cancer ( MCRC ) patients ( pts ) . - pubmed
Almost half the patients on peritoneal dialysis are diabetic and glycemic control is essential to improve both patient and technique survival . - pubmed
METHODS : Mice were anesthetized and then infected intranasally by dropping 0.05 mL of influenza virus suspension ( 4xLD50 ;) except normal group . - pubmed
However , inactivated vaccines are based on TBEV strains of the heterologous Far Eastern or the European subtypes isolated 40 - 77 years ago . - pubmed
To analyze the efficacy of the available vaccines against currently prevailing TBEV isolates of the Siberian subtype , mice were immunized subcutaneously three times ( one group per each vaccine ) . - pubmed
BACKGROUND : Children with specific language impairments carry a high risk for the development of reading and writing disorders . - pubmed
We reviewed prospectively collected data in a consecutive series of 193 patients with laryngeal dystonia who were seen at St. Vincent 's Hospital between 1991 and 2011 . - pubmed
Patients with adductor SD , stridor , extra - laryngeal dystonia and male patients had relatively better treatment outcomes . - pubmed
Cross - cultural adaptation , reliability , internal consistency and validation of the Hand Function Sort ( HFS ) for French speaking patients with upper limb complaints . - pubmed
METHODS : 150 patients with various upper limbs impairments were recruited in a rehabilitation center . - pubmed
However , in debilitated people with immune deficiencies , Candida can cause serious invasive infections with high mortality . - pubmed
Even though some critical points about the BMSC - based therapy model still need clarification , we hope to develop more reliable pharmacological or biotechnical strategies utilizing the stem cell for the eventual treatment of humans with AKI , based on these studies and the understanding of mechanism of renal protection by BMSCs . - pubmed
Postoperative complications were seen in 16 % ( 7 patients ) . - pubmed
These 7 patients had the following complications : wound dehiscence ( 7 % [ n = 3 ] ) , osteomyelitis ( 7 % [ n = 3 ] ) , abscess development ( 4 % [ n = 2 ] ) , bone necrosis ( 2 % [ n = 1 ] ) , and severe nonocclusion ( 2 % [ n = 1 ] ) . - pubmed
Dietary supplementation with docosahexanoic acid ( DHA ) increases red blood cell membrane flexibility in mice with sickle cell disease . - pubmed
Humans and mice with sickle cell disease ( SCD ) have rigid red blood cells ( RBCs ) . - pubmed
Drug induced hepatotoxicity was observed in the older patients . - pubmed
CONCLUSION : The study showed that the risk of development of drug - induced hepatotoxicity following treatment with first line anti - tuberculosis treatment increased with the age of the patient . - pubmed
Here , we investigated the antitumorigenic effects of curcumin and 3 acetyl-11 - keto - beta - boswellic acid ( AKBA ) on modulation of specific cancer - related miRNAs in colorectal cancer cells and validated their protective effects in vivo using a xenograft mouse model . - pubmed
Furthermore , we demonstrated in a mouse xenograft model that both curcumin and AKBA treatments suppressed tumor growth , which corresponded with alterations in the expression of miR-34a and miR-27a , consistent with our in vitro findings . - pubmed
We report the case of an infant diagnosed as cutaneous mastocytosis and seasonal allergies . - pubmed
METHODS : Three eyes of 3 patients with pseudophakic bullous keratopathy underwent the procedure in this single - center , prospective interventional series . - pubmed
Our results are generally comparable to previous PM2.5 and dLAN reports conducted on mice and implicate PM2.5 and dLAN as potential factors contributing to depression and anxiety . - pubmed
Immunostimulant and chemoprotective effect of vivartana , a polyherbal formulation against cyclophosphamide induced toxicity in Swiss albino mice . - pubmed
Dengue has spread to new geographic areas affecting both children and adults , and it has become a global threat . - pubmed
Rituximab - induced interstitial lung disease in a patient with follicular lymphoma : A rare case report . - pubmed
Patient developed exertional dyspnea and dry cough after the fourth cycle of rituximab - based chemotherapy . - pubmed
[ Pathogenesis and prevention of secondary thromboses and thromboembolic complications in patients with endured lower limb deep vein thrombosis ] . - pubmed
The study included a total of 84 patients presenting with lower limb deep vein thrombosis . - pubmed
The patients of the Study Group ( n=44 ) were examined for thrombophilic states , revealing of which was followed by prescribing specific lifelong therapy aimed at correction of the alterations revealed . - pubmed
The Study Group patients demonstrated less relapses of deep vein thromboses as compared with the Control Group patients . - pubmed
A conclusion was drawn on the necessity of carrying out further studies aimed at altering the recommended therapeutic regimen for patients in the remote period after sustained deep vein thrombosis . - pubmed
The protective effects of carvacrol and thymol against paracetamol - induced toxicity on human hepatocellular carcinoma cell lines ( HepG2 ) . - pubmed
These findings provide novel insights into a possible molecular mechanism by which childhood maltreatment heightens the risk for relapse in cocaine - dependent individuals . - pubmed
Our results suggest that , as in patients , chronic pelvic pain is a consequence of prostate inflammation . - pubmed
Intraoperative Tension Pneumothorax in a Patient With Remote Trauma and Previous Tracheostomy . - pubmed
Many trauma patients present with a combination of cranial and thoracic injury . - pubmed
We report a case of a 25 - year - old patient with remote thoracic trauma , who developed an intraoperative tension pneumothorax and hemodynamic instability while undergoing an elective cranioplasty . - pubmed
The intraoperative patient assessment was made even more challenging by unexpected massive blood loss from the surgical site . - pubmed
Timely recognition and management of intraoperative pneumothorax along with adequate blood replacement stabilized the patient and helped avoid an unfavorable outcome . - pubmed
This case highlights the risks of intraoperative pneumothorax in trauma patients , which may develop even months after injury . - pubmed
Although Sapovirus ( Caliciviridae ) has been accepted as one of the causes of acute gastroenteritis worldwide , little is known about the genetic characteristics of the whole genome of sapoviruses in China , especially those that infect humans . - pubmed
In this review , we evaluate the existing body of evidence and offer an approach to the management of patients with ARAS in light of the current literature . - pubmed
7 patients died within 30 days ; none of the deaths were recorded as procedure - related . - pubmed
Capnocytophaga canimorsus is a dog oral commensal that causes rare but severe infections in humans . - pubmed
We describe nine different serovars ( A to I ) , and this serotyping scheme allowed typing of 25/25 isolates from human infections but only 18/52 isolates from dog mouths , indicating that the repertoire of capsules in the species is vast . - pubmed
Capsular serotyping would thus allow identification of virulent isolates in dogs , which could contribute to the prevention of these infections . - pubmed
Experiments in rodents showed that severe chronic stress can reduce the number of dopaminergic neurons in the substantia nigra pars compacta ( SNc ) ; the same cells that are lost in PD . - pubmed
All patients developed the same symptoms of ventilatory and hemodynamic decompensation , beginning with a reduction in end - tidal carbon dioxide , arterial desaturation , and cyanosis on the upper trunk , and rapidly progressed to hypotension and 2 cardiac arrests . - pubmed
Analysis on survival and prognostic factors in patients with resectable pancreatic adenocarcinoma . - pubmed
A total of 96 patients who underwent curative resection for pancreatic cancer were included . - pubmed
Muli bamboo ( Melocanna baccifera ) leaves ethanolic extract a non - toxic phyto - prophylactic against low pH stress and saprolegniasis in Labeo rohita fingerlings . - pubmed
In the 2nd experiment , toxicity study was carried on Labeo rohita fingerlings ( average length of 10.3 + - 1.5 cm and weight 18.5 + - 1.5 g ) using BLAL ( Bamboo Leaf Alcoholic ) extract and it did not show any mortalities in fish even at the dose of 20 g kg-1 body weight , which can be regarded as virtually non - toxic with minimal effect . - pubmed
In the 4th experiment , fish were exposed to multiple stressors like low pH stress , and Saprolegnia parastica infection after feeding with BLAL extract ( 0.1 % ) based feed for 7 days . - pubmed
Thus , it can be concluded that the BLAL has the potentiality to be used as a non - toxic phyto - prophylactic which can induce non - specific immune response , reduces the low pH stress responses and increases the resistance against saprolegniasis under neutral pH condition in rohu fingerlings . - pubmed
The aim of this study was to describe the clinical characteristics of PHPT patients at our center from January 2005 to December 2016 . - pubmed
METHODS : Two hundred sixty patients with PHPT visiting Shanghai Jiao Tong University Affiliated Sixth People 's Hospital were enrolled retrospectively . - pubmed
RESULTS : Among all patients , 73.1 % had symptomatic PHPT , while the number of symptomatic and asymptomatic patients increased 1 to 2.5 times and 1.5 to 3 times , respectively , from 2005 to 2016 . - pubmed
CONCLUSIONS : Most patients with PHPT in China still exhibit classic clinical and biochemical features . - pubmed
BACKGROUND : The non - tuberculous mycobacteria include those mycobacterium species that are not members of the Mycobacterium tuberculosis complex , the causative agent of pulmonary tuberculosis and Mycobacterium leprae . - pubmed
CASE SUMMARY : We report a case of a 62 - year - old man who developed external popliteal sciatic nerve paralysis after 22 days of therapy with daptomycin . - pubmed
Background : The skeletal muscle toxicity that accompanies the chemotherapy drug doxorubicin ( DOX ) may lead to cancer patient weakness and fatigue . - pubmed
The grimace scale reliably assesses chronic pain in a rodent model of trigeminal neuropathic pain . - pubmed
The limited success in translating basic science findings into effective pain management therapies reflects , in part , the difficulty in reliably assessing pain in experimental animals . - pubmed
Mice and rats were subjected to CCI - ION , and tested for changes in mechanical hypersensitivity and in grimace scores , 10 or more days after surgery . - pubmed
Fentanyl reversed the changes in rat grimace scale scores , suggesting that these scores reflect pain perception . - pubmed
These findings validate the grimace scale as a reliable and sensitive metric for the assessment of ongoing pain in a rodent model of chronic , trigeminal neuropathic pain . - pubmed
Here , we studied the infection status of 815 human blood donors and of 803 sympatric dogs from five , newly endemic , areas in Northwestern Italy . - pubmed
No significant correlation between the infection status of dogs and that of their human owners was found , but L. - pubmed
Conclusion : Given the current understanding of mechanical transmission of pathogens in both humans and animals by insects belonging to the Tabanidae family which also includes Chrysops , it is plausible that the same mechanism may hold true for hepatitis B also . - pubmed
In this review , we have summarized the potential health benefits of Scutellaria and its active components also the underlying mechanism of cytotoxicity and antitumor activity . - pubmed
D - dimer has been used as both a diagnostic and prognostic biomarker in the assessment of patients with venous thromboembolism , but its prognostic value in the setting of arterial acute coronary syndromes ( ACS ) and the ability of pharmacotherapy to reduce D - dimer in ACS is less well characterized . - pubmed
SELECTION CRITERIA : 1 ) Randomized controlled trials , 2 ) involving older adults ( & gt;60 years old ) , 3 ) suffering from mental illness or cognitive decline , 4 ) comparing mind - body interventions with a control group . - pubmed
METHODS : We enrolled 30 independently living patients aged 18 - 75 years who had undergone THA as a treatment for primary or secondary osteoarthritis ( OA ) between December 2015 and February 2017 . - pubmed
The PQQ-42 strain produces more EPS ( 0.36 g l-1 ) than the PQQ-44 strain ( 0.15 g l-1 ) , whose chemical compositions also differ . - pubmed
METHODS : A cross - sectional study was conducted to observe diabetic patients in the internal medicine department in Dr M. Djamil Hospital , Padang , Indonesia . - pubmed
PURPOSE : To evaluate real - world evidence for young Japanese patients with rhegmatogenous retinal detachment ( RRD ) by retrospectively examining surgical procedures and clinical outcomes in the Japan Clinical Retina Study group . - pubmed
METHODS : This was a multicentre retrospective study of the medical records of 562 young patients ( 384 males and 178 females ; mean age : 33.0 + - 11.8 years ) who had been diagnosed with RRD and who underwent surgical procedures in participating centres during the period between April 2013 and August 2016 . - pubmed
CONCLUSION : Scleral buckling ( SB ) and PPV were chosen with almost equal frequency for young patients with RRD . - pubmed
Diagnostic usefulness of differential time to positivity in neutropenic cancer patients with suspected catheter - related candidemia . - pubmed
In affected patients , renal function may progressively decline up to end - stage renal disease ( ESRD ) , and approximately 10 % of those with ESRD are affected by ADPKD . - pubmed
We evaluated the renoprotective effect of octreotide - LAR in ADPKD patients at high risk of ESRD because of later - stage ADPKD . - pubmed
METHODS AND FINDINGS : We did an internally funded , parallel - group , double - blind , placebo - controlled phase III trial to assess octreotide - LAR in adults with ADPKD with glomerular filtration rate ( GFR ) 15 - 40 ml / min/1.73 m2 . - pubmed
Over a median ( IQR ) 36 ( 24 to 37 ) months of follow - up , 9 patients on octreotide - LAR and 21 patients on placebo progressed to a doubling of serum creatinine or ESRD ( composite endpoint ) ( hazard ratio [ HR ] [ 95 % CI ] adjusted for age , sex , baseline serum creatinine , and baseline TKV : 0.307 [ 0.127 to 0.742 ] , p = 0.009 ) . - pubmed
Among 63 patients with chronic kidney disease ( CKD ) stage 4 , 3 on octreotide - LAR and 8 on placebo progressed to ESRD ( adjusted HR [ 95 % CI ] : 0.121 [ 0.017 to 0.866 ] , p = 0.036 ) . - pubmed
Three patients on placebo had a serious renal cyst rupture / infection and 1 patient had a serious urinary tract infection / obstruction , versus 1 patient on octreotide - LAR with a serious renal cyst infection . - pubmed
BACKGROUND : We conducted a comparative survival analysis between primary androgen deprivation therapy ( PADT ) and radical prostatectomy ( RP ) based on nationwide Korean population data that included all patients with prostate cancer . - pubmed
MATERIALS AND METHODS : This study enrolled 4,538 patients with prostate cancer from the National Health Insurance Service ( NHIS ) database linked with Korean Central Cancer Registry data who were treated with PADT or RP between January 1 , 2007 , and December 31 , 2014 . - pubmed
RESULTS : LAB strains were mixed at equal proportions ( 1:1 ) according to mathematical planning of experiments . - pubmed
The antifungal effect of the most active strain Lactobacillus rhamnosus MDC 9661 in the associations with other LAB strains was partly decreased . - pubmed
The co - cultivation of some strains , like L. - pubmed
Therefore , the objectives of hypercholesterolaemia control in patients at high cardiovascular risk are becoming ever stricter . - pubmed
It is to be hoped that the new guidelines that are to be issued soon by various scientific societies will define in greater detail the patients and the conditions in which we can use PCSK9i , drugs which currently constitute the greatest advance in hypercholesterolaemia of recent decades . - pubmed
PURPOSE : We introduce two validated single ( SH ) and dual hormone ( DH ) mathematical models that represent an in - silico virtual patient population ( VPP ) for type 1 diabetes ( T1D ) . - pubmed
We present validation results comparing these virtual patients with true clinical patients undergoing AP control and demonstrate that the virtual patients behave similarly to people with T1D. - pubmed
We evaluated the SH - VPP and DH - VPP on a clinical data set of 20 people with T1D who participated in a 3.5 - day outpatient AP study . - pubmed
We compared percent time in target range ( 70 - 180 mg / dL ) , time in hypoglycemia ( & lt;70 mg / dL ) and time in hyperglycemia ( & gt;180 mg / dL ) for both the virtual patients and the actual patients . - pubmed
RESULTS : The subjects in the SH - VPP performed similarly vs. the actual patients ( time in range : 78.1 + - 5.1 % vs. 74.3 + - 8.1 % , p = 0.11 ; time in hypoglycemia : 3.4 + - 1.3 % vs. 2.8 + - 1.7 % , p = 0.23 ) . - pubmed
The subjects in the DH - VPP also performed similarly vs. the actual patients ( time in range : 75.6 + - 5.5 % vs. 71.9 + - 10.9 % , p = 0.13 ; time in hypoglycemia : 0.9 + - 0.8 % vs. 1.3 + - 1 % , p = 0.19 ) . - pubmed
Recent clinical trials using cancer and non - cancer patients with chronic fatigue have shown the benefit of Molecular Replacement Therapy plus antioxidants in restoring mitochondrial electron transport function , reducing moderate to severe chronic fatigue and protecting mitochondrial and other cellular structures and enzymes from oxidative or other damage due to cytotoxic therapy . - pubmed
In animal models of IUGR , long - term persistent changes in both DNA methylation and expression of genes implicated in metabolic processes have been repeatedly reported . - pubmed
Findings from human studies confirming the role of epigenetic mechanisms in linking early - life adverse experiences to the risk for T2D in adult life are scarce compared to data from animal studies , mainly because of limited access to suitable biological samples . - pubmed
Cysticercosis cellulosa cutis is caused by larval stage of Taenia solium . - pubmed
In this study , we find that miR-204 - 5p expression is reduced in PCa tissues and serum sample with bone metastasis compared with that in PCa tissues and serum sample without bone metastasis , which is associated with advanced clinicopathological characteristics and poor bone metastasis - free survival in PCa patients . - pubmed
Diffuse variants of scalp Lichen Planopilaris : clinical , trichoscopic and histopathologic features of 40 patients . - pubmed
OBJECTIVES : The medical features of 40 patients affected by a diffuse hair thinning associated with a long - lasting history of pruritus and erythema of the scalp and a histopathological diagnosis of LPP were reviewed . - pubmed
RESULTS : Eighteen patients were diagnosed with FAPD and two patients with CPHL . - pubmed
CONCLUSIONS : In patients complaining of a long - lasting history of scalp erythema , itching / dysesthesia and diffuse hair thinning it 's advisable to consider diffuse variants of LPP . - pubmed
Brain functional connectivity data enhance prediction of clinical outcome in youth at risk for psychosis . - pubmed
This study assesses a combined clinical and resting - state fMRI prediction model in 137 adolescents and young adults at Clinical High Risk ( CHR ) for psychosis from the Shanghai At Risk for Psychosis ( SHARP ) program . - pubmed
OBJECTIVE : Impairments generally persist when children diagnosed with attention - deficit / hyperactivity disorder ( ADHD ) mature into adolescence . - pubmed
North American hibernating bat species are threatened by the psychrophilic fungus Pseudogymnoascus destructans ( Pd ) causing the disease called white - nose syndrome ( WNS ) with unprecedented mortality rates . - pubmed
We identified differentially expressed proteins for acute phase response , constitutive and adaptive immunity , oxidative stress defense , metabolism and structural proteins of exosomes and desmosomes , suggesting a systemic response against Pd in North American M. - pubmed
Results : In this study , 625 laboratory - confirmed COVID-19 patients were enrolled ; among them , 179 patients without an initial CT at admission and 25 patients aged < 18 years old were excluded and 421 patients were included in analysis . - pubmed
To assess if there is a correlation between femoral neck - shaft angle ( NSA ) and the distance of the ischiofemoral space ( IFS ) and quadratus femoris space ( QFS ) and to determine the prevalence of quadratus femoris ( QF ) edema in patients with hip pain . - pubmed
A retrospective case series was conducted involving 100 consecutive hip or pelvis magnetic resonance imaging scans on patients presenting with hip pain . - pubmed
A similar decrease in ADCC titers was observed in Hvem-/- mice vaccinated with an alternative HSV vaccine candidate ( dl5 - 29 ) or an unrelated vesicular stomatitis virus - vectored vaccine . - pubmed
METHODS : We included 101 MS patients and 77 healthy subjects in this study . - pubmed
BACKGROUND : Although pelvic osteotomy ( PO ) is an important surgical procedure that can alleviate symptoms and potentially slow progression of osteoarthritis in patients with development dysplasia of the hip , some patients eventually require conversion to total hip arthroplasty ( THA ) . - pubmed
METHODS : Forty nine patients with a history of prior PO who underwent conversion THA at a single institution were matched at a 1:3 ratio based on the date of surgery , age , gender , and body mass index with 147 developmental dysplasia of the hip patients who underwent primary THA without prior PO . - pubmed
RESULTS : Patients with prior PO required more supplemental screw fixation for the acetabular component ( 59.2 % vs 38.1 % , P = .016 ) , more autologous bone grafting ( 24.5 % vs 11.6 % , P = .048 ) , had a longer mean operative time ( 106.0 vs 79.8 minutes , P < .001 ) , and greater estimated blood loss ( 350.0 vs 206.8 mL , P = .015 ) . - pubmed
We discuss the most common temporary mechanical circulatory support ( tMCS ) devices used for patients in cardiogenic shock , including the intra - aortic balloon pump ( IABP ) , transvalvular axial flow support systems ( Impella ) , the Tandem collection , and extracorporeal membrane oxygenation ( ECMO ) . - pubmed
Objective : To describe the frequency and predisposing factors of aortic structural disease among patients with biopsy - proven giant cell arteritis ( GCA ) . - pubmed
Method : A retrospective review identified all patients with biopsy - proven GCA from 1998 to 2013 with aortic imaging . - pubmed
Conclusion : Thoracic aortic aneurysm / dilatation was seen in 8 % of patients at baseline . - pubmed
Among patients without aortic disease , the cumulative incidence of aortic disease was 10 % at 5 years after diagnosis . - pubmed
This note reports the first finding of clown beetles ( Coleoptera , Histeridae ) in a hive aggregation of stingless and honey bees in natural conditions and expands the known distribution of the species to the state of Espirito Santo , the second record in the Brazilian Atlantic Forest . - pubmed
, diabetes and obesity ) has seriously affected human health and life safety worldwide . - pubmed
Both animal and clinical studies have proved that BBR has good therapeutic effects on these five metabolic diseases . - pubmed
All - cause death occurred in 2.5 % of patients assigned to experimental and 2.9 % of patients assigned control therapy ( hazard ratio [ HR ] , 0.91 , 95 % CI , 0.75 - 1.11 ; P=0.37 ) . - pubmed
Overall , patients treated with experimental versus control therapy showed no significant difference in terms of myocardial infarction ( HR , 1.02 [ 0.85 - 1.22 ] , P=0.81 ) , stent thrombosis ( HR , 1.02 [ 0.87 - 1.20 ] , P=0.83 ) , or stroke ( HR , 1.01 [ 0.68 - 1.49 ] , P=0.96 ) . - pubmed
Conclusions In patients treated with percutaneous coronary intervention and stenting , assigned to a strategy of early aspirin discontinuation versus DAPT , the risk of death and ischemic events is not significantly different but the risk of bleeding is lower . - pubmed
Subsequently , hydroxycarbamide proved efficacious in adults with SCA and was Food and Drug Administration ( FDA)-approved in 1998 . - pubmed
Parallel efforts to develop curative therapies using haematopoietic stem cell transplant and gene therapy provide individuals with SCD multiple treatment options . - pubmed
The target of the current research is to assess the antiarthritic efficacy of BM - MSCs ( 106 cells / rat at 1 , 6 , 12 and 18 days ) and IMC ( 2 mg / kg body weight / day for 3 weeks ) either alone or concurrently administered against complete Freund 's adjuvant - induced arthritic rats . - pubmed
Patients exhibited changes in the thalamus , posterior thalamic radiations and sagittal stratum on brain MRI and demonstrated impaired cognitive performance , specifically in the executive and visuospatial domains . - pubmed
Nursing of a patient with stroke and improvement of the dememted state with agressive care ] . - pubmed
Clinical review of cervical spine injuries in children . - pubmed
Clinical presentation is made of 18 cervical fractures occurring in children age 15 and under . - pubmed
The data suggest that the elicited imitation procedures can be effectively used to increase the precision of the evaluation and clinical programming of children with language disorders . - pubmed
Paraplegia developed in a 70 - year - old man after resection of a ruptured abdominal aortic aneurysm during which aortic occlusion time was 45 minutes . - pubmed
Only four patients have previously been reported to recover from paraplegia produced in this manner . - pubmed
Paraplegia is more common in patients with hypotension and when backbleeding from the lumbar arteries has been poor . - pubmed
Fourteen cases of patients with photoconvulsive response during intermitent luminous stimulation ( eleven women and three men ) are reviewed . - pubmed
Sustained and transient ganglion cells in the cat 's retina : spatial distribution of centre and surround receptive field mechanisms . - pubmed
[ Heterotopic ossifications in a patient with severe craniocerebral trauma ] . - pubmed
Patients with severe head injury and fractures of joints or of long bones often show a hypertrophic callus formation which leads to a rapid consolidation of a fracture but can also lead to an ankylosis of the joints . - pubmed
Seasonal occurrence of Karoo paralysis in Angora goats in relation to the infestation density of female Ixodes rubicundus . - pubmed
The seasonal occurrence of Karoo paralysis in relation to the infestation density of female Ixodes rubicundus was investigated in an enzootic area of the southwestern Orange Free State , South Africa . - pubmed
Only the young goats became paralysed and their infestation densities ( female ticks kg-1 host body weight ) were significantly higher than those of healthy animals . - pubmed
Monoclonal antibody B72.3 immunoscintigraphy in the follow - up of patients with colorectal cancer . - pubmed
We describe EEG findings and clinical outcomes of 24 Alzheimer ( AD ) patients over a 3 year follow - up period . - pubmed
At year 3 , only 2 patients still had normal EEGs and mild dementia , probably representing a subgroup of AD with a benign course , 7 patients needed institutional care and 3 had died . - pubmed
The results support the idea of heterogeneity of AD patients and suggest that EEG may provide valuable information for prediction of outcome . - pubmed
[ Clinical usefulness of quantitative two - dimensional echocardiographic analysis of segmental kinesis of the left ventricle in monitoring of patients with neoplasms treated with anthracyclines ] . - pubmed
To determine whether serial quantitative two - dimensional echocardiographic analysis of left ventricular wall motion could be effective in selecting patients in whom anthracycline treatment must be stopped , 26 patients ( 18 M and 8 F , mean age 10 + /- 3 , range 6 to 16 years ) with malignancy , receiving doxorubicin or daunomycin were followed up . - pubmed
The following distribution of left ventricular contraction abnormalities was noted : septal , anteroseptal and posteroseptal akinesis with posterior wall hypokinesis in one patient ; septal , anteroseptal and posteroseptal akinesis with anterolateral free - wall hypokinesis in another ; septal , anteroseptal and posteroseptal hypokinesis in four ; lateral and posterolateral free - wall hypokinesis in one ; septal , anteroseptal , posteroseptal and posterior hypokinesis in four . - pubmed
The drug was discontinued in only two patients with akinesis , since we regarded this contraction abnormality as a predictive index of more serious and extensive myocardial damage . - pubmed
A femoroperoneal bypass using a cryopreserved human saphenous allograft was performed on a patient who presented with critical ischemia of the left lower extremity . - pubmed
The patient died of myocardial infarction 48 hours later and the graft was examined histologically . - pubmed
The histologic changes that occur in cryopreserved venous allografts are similar in experimental and human material and may be the result of anoxia of the vessel wall rather than immunologic mechanisms . - pubmed
In 85 patients background factors such as diabetes , age , sex and side of operation were analysed and found not to influence the degree of edema . - pubmed
Within the leg elevation group there was , like in patients without special treatment , less swelling if the distal anastomosis was performed above the knee and if a prosthetic graft was used . - pubmed
In these cases leg elevation seemed to prevent swelling with significantly less edema than corresponding patients treated without leg elevation . - pubmed
METHOD : Fifty - nine outpatients with major depression with endogenous features , according to Research Diagnostic Criteria , were stratified into more severe ( score of 20 or more on the Hamilton Rating Scale for Depression ; N = 38 ) or less severe ( Hamilton score of 19 or less ; N = 21 ) subgroups . - pubmed
CONCLUSIONS : These results partially replicate the National Institute of Mental Health 's Treatment of Depression Collaborative Research Program 's findings of poorer response to cognitive behavior therapy in patients with Hamilton scale scores of 20 or more . - pubmed
Identification of patients at increased risk for potentially malignant arrhythmias . - pubmed
Appropriate identification of patients at high risk for malignant ventricular arrhythmias requires subclassification by disease entity , historic information about syncopal episodes , noninvasive testing , and invasive electrophysiologic studies in selected patients . - pubmed
We report on a patient with small - cell carcinoma of the esophagus treated with combination chemotherapy consisting of cyclophosphamide , vincristine , and VP-16 followed by local radiation therapy . - pubmed
A report is given on the natural history of multi - infarct dementia ( MID ) in 94 patients over a period of 5 years and describes neuroimaging criteria that may be used in order to more reliably separate vascular ( VD ) from primary degenerative types of dementia ( DTD ) . - pubmed
The annual mortality rate of MID patients was 13 % . - pubmed
The typical patchy pattern found in almost half of the patients with VD , and significant differences in 5 - 7 Hz range as shown by EEG mapping can also be used for increasing the accuracy of the clinical diagnosis . - pubmed
DCB exhibited both direct and H2O2 - dependent mutagenicity to both tester strains TA98 and TA98/1,8 - DNP6 . - pubmed
DCB , in contrast to its effects in tester strains TA98 , was not mutagenic to TA100 and TA102 either directly or in the presence of H2O2 . - pubmed
Graft versus leukemia effect in man : the relapse rate of acute leukemia is lower after allogeneic than after syngeneic marrow transplantation . - pubmed
To determine whether allogeneic bone marrow transplantation ( BMT ) is associated with a graft vs leukemia ( GVL ) effect in man , the relapse rate of acute leukemia after allogeneic BMT was compared with that occurring after syngeneic ( genetically identical twin ) BMT . - pubmed
Experimentally induced photosensitization in cattle with Cooperia pedunculata . - pubmed
Photosensitization was induced in 2 Charolais heifers following administration of a mixture of air - dried , ground , green ( 75 % ) and dead ( 25 % ) leaves of the south Texas forb , Cooperia pedunculata , and subsequent exposure to sunlight . - pubmed
Plant material used in this study was collected from a pasture where natural cases of primary bovine photosensitization were occurring . - pubmed
A second heifer developed signs of mild photosensitization following administration of plant material at 1.7 g / kg / d for 4 days . - pubmed
Clinical and pathologic findings of this trial were consistent with the primary form of photosensitization observed in natural cases seen in cattle of south Texas exposed to this plant . - pubmed
Quantitative transplantation techniques have been employed to study radiogenic cancer initiation frequency and cell interactions during promotion / progression in grafted clonogenic rat thyroid epithelial cells . - pubmed
aureus - infected milk samples ( 7 % ) from cows with chronic staphylococcal mastitis . - pubmed
Failure to detect leukocidin in most mastitic milk samples with this assay indicated that , if leukocidin is produced in the bovine mammary gland during chronic staphylococcal mastitis , the concentration of the toxin may be too low to produce cytolytic effects on neutrophils . - pubmed
The mixture of capped in vitro transcripts from all three clones produced normal CCMV infections in barley protoplasts and cowpea plants . - pubmed
Histological and electrophysiological studies were performed in Lewis rats with experimental allergic encephalomyelitis ( EAE ) to determine the cause of the neurological signs . - pubmed
It is concluded that demyelination - induced conduction block in this region is an important cause of hindlimb weakness and paralysis in Lewis rats with EAE . - pubmed
Toxicity of pyrethroids to Aedes aegypti larvae in relation to temperature . - pubmed
The influence of temperature on the toxicity of the pyrethroids cypermethrin , permethrin , fenvalerate , d - phenothrin , flucythrinate and bioallethrin to 3rd instar Aedes aegypti larvae was determined . - pubmed
Blood samples from 23 subjects with chronic renal failure and 19 controls were tested using thrombelastography and other hematologic tests . - pubmed
In vitro and ex vivo effect of cimetidine on human platelet aggregation . - pubmed
The TBS is effective and may have wide application in producing amplification in good sound fidelity when used in patients who have external canal , middle ear , or eustachian tube disease that is poorly corrected by surgery or conventional hearing aids . - pubmed
In order to determine whether superior cervical ganglion ( SCG ) fibers sprouting into the hippocampus contribute to behavioral recovery , 31 Sprague - Dawley rats were first trained on a forced - choice task . - pubmed
Early responses of liver to cortisone in alloxan - diabetic rats . - pubmed
The efficacy of fine - detail radiography in the evaluation of patients with rheumatoid arthritis . - pubmed
Effect of halothane anesthesia on experimental Salmonella peritonitis in mice . - pubmed
Cochlear otosclerosis : a human temporal bone report . - pubmed
[ On the immunization of white mice against ectromelia by means of an active vaccine virus . - pubmed
Effect of immunosuppressive drug therapy on blood urea nitrogen concentration in dogs with azotemia . - pubmed
Azotemic dogs receiving prednisone and azathioprine to enhance renal allograft survival had higher blood urea nitrogen ( BUN):serum creatinine ( SC ) ratios , when compared with nontreated dogs with induced azotemia . - pubmed
However , dogs with naturally occurring renal failure had BUN : SC ratios that were similar to those for dogs receiving the catabolic drugs . - pubmed
It was concluded that even though catabolic drugs may influence BUN : SC ratios , the multiplicity of other factors affecting BUN and SC may interact to cause a wide range of BUN : SC ratios under conditions of naturally occurring primary renal failure in the dog . - pubmed
Fatty liver syndrome or hepatic lipidosis ( HL ) is a condition thought to contribute to an increased incidence of peripartum disease , reduced response to therapy and decreased fertility in dairy cows . - pubmed
The effect of alcohol on the toxicity of acetaminophen in mice . - pubmed
The present report describes our results in using alcohol as an antidote for acetaminophen overdose in the mouse model . - pubmed
Alcohol thus appears to be an effective antidote for acetaminophen overdose in the mouse model , when given at an appropriate time and dose . - pubmed
Four patients with aneurysmal bone cysts of the rib are presented and previously reported cases reviewed . - pubmed
Most steroid - dependent asthmatic patients can be successfully controlled with the drug , at least most of the time , and the therapeutic effect is dose dependent . - pubmed
It is important that patients treated with steroid aerosols continue to receive other effective therapeutic agents , notably adrenergic drugs , particularly by aerosol , and theophylline compounds ; that they learn how to inhale the aerosol properly ; and , most important , that they promptly start taking oral steroids when they experience an exacerbation of asthma . - pubmed
A breeding study to control chronic progressive nephrosis in rats . - pubmed
The selection of low excretor males for breeding stock appears to offer a practical basis for minimizing the total expression of chronic progressive nephrosis in this strain of rat . - pubmed
The Schaefer seroagglutination test is useful in epidemiologic studies of nontuberculous mycobacteria , especially the Mycobacterium avium - intracellulare - scrofulaceum complex . - pubmed
We assessed the long - term results of our experience with 109 patients with end - stage cardiopulmonary disease who underwent primary combined heart - lung transplantation at Stanford University Medical Center between March 1981 and January 1994 . - pubmed
Causes of death included hemorrhage ( five patients ) , infection ( 21 ) , rejection ( one ) , nonspecific pulmonary failure ( four ) , graft coronary artery disease ( six ) , and obliterative bronchiolitis ( eight ) . - pubmed
Only 20 % + /- 3.9 % of patients were free from any infection 3 months after transplantation . - pubmed
Although graft coronary artery disease developed less frequently than in patients after isolated heart transplantation ( 90 % + /- 4.6 % of patients were free of graft coronary artery disease at 5 years ) , obliterative bronchiolitis remains a major long - term complication and cause of morbidity and mortality . - pubmed
Involvement of free radicals in cisplatin - induced emesis in Suncus murinus . - pubmed
The participation of free radicals in cisplatin - induced emesis was investigated in the house musk shrew , Suncus murinus . - pubmed
A patient is described who developed an intramural haematoma of the oesophagus shortly after variceal endoscopic sclerotherapy . - pubmed
Clinically , sensory or sympathetic damage caused incontinence , but sympathectomy also caused high pressure waves , which may cause upper tract damage and treatment resistant incontinence in patients . - pubmed
cereus H.1 reacted not only with the homologous specific antigen but also reacted with the flagellar antigens of 23 strains of B. - pubmed
cereus also reacted with flagellar antigens of 21 strains of Bacillus thuringiensis by ELISA . - pubmed
Effects of washing acid injuries to the skin with water : an experimental study using rats . - pubmed
A skin acid injury model has been constructed using SD rats and 1N HCl . - pubmed
After inflicting an acid injury , the subcutaneous tissue pH of control animals reached its minimum value at the seventh minute , and had not recovered to the pre - experimental level by the 60th minute . - pubmed
[ Eye lesions in patients with pulmonary sarcoidosis ] . - pubmed
Sarcoidosis involvement of the eyes was revealed in 36 % of patients with sarcoidosis of the respiratory organs . - pubmed
Natural history of abnormal conduction and its relation to prognosis in patients with dilated cardiomyopathy . - pubmed
To investigate the natural history of disturbances in ventricular activation , atrioventricular conduction , and ventricular cavity size , we retrospectively studied 58 patients from a total of 296 patients with dilated cardiomyopathy seen within 4 years . - pubmed
PATIENTS : Forty - six patients with definite chronic progressive MS ; 20 received treatment and 26 were in a nontreatment comparison group ( " waiting list " ) . - pubmed
RESULTS : The patients were divided into four outcome groups ( failure , fair , good , and excellent ) based on a scoring table that adds or subtracts points while evaluating three main areas : percentage of excess weight loss , changes in medical conditions , and assessment of quality of life . - pubmed
Magnetic resonance imaging analysis of left ventricular function in normal and spontaneously hypertensive rats . - pubmed
We have used magnetic resonance imaging ( MRI ) to examine acute morphological changes in the left ventricle throughout the cardiac cycle in normal Wistar Kyoto rats ( WKY ) and also to follow the development of chronic changes in spontaneously hypertensive rats ( SHR ) . - pubmed
The Batista operation was performed in 30 patients ( 25 men and 5 women , mean age 47 years ) to treat cardiac failure due to non - ischemic cardiomyopathy , mostly idiopathic dilated cardiomyopathy , from December 1996 to June 1998 . - pubmed
Seven patients required emergency surgery because of on - going shock and 23 patients were operated electively . - pubmed
Effects of Ehrlich ascites carcinoma cells on the responses of non - pregnant and pregnant uterine smooth muscles of mice to oxytocin and acetylcholine . - pubmed
On the other hand , induction of pregnancy in control non - tumor bearing mice significantly increases the sensitivity of the uterine smooth muscles to oxytocin as well as to ACh . - pubmed
In tumor bearing mice , the induction of pregnancy significantly reduced the sensitivity of the uterine smooth muscles to oxytocin and ACh when compared with the uterine muscles obtained from pregnant non - tumor bearing mice . - pubmed
It is also providing an animal model in which to test therapies aimed at reducing hemodynamic stress and the collapse of the aortic matrix during dissecting aneurysm . - pubmed
The patients were nine women with mild preeclampsia and , for comparison , nine control women matched for gestation and parity . - pubmed
RESULTS : Women with mild preeclampsia had higher norepinephrine levels throughout 25 h , and lower systemic prostacyclin production as measured by the urinary 2,3 - dinor-6 - keto PGF1 alpha excretion during the daytime . - pubmed
The majority of HD patients require intravenous iron therapy to achieve the hematocrit levels that correspond to improved outcome measures . - pubmed
Specifically , no data unequivocally confirm that iron overload from parenteral iron contributes to all - cause patient morbidity or mortality . - pubmed
The rat middle cerebral artery ( MCA ) was occluded by a thrombus induced by photochemical reaction between green light and the photosensitizer dye , Rose Bengal . - pubmed
ONO-5046 at doses of 10 and 30 mg / kg / h significantly ( p<0.05 and p<0.01 , respectively ) reduced the size of cerebral damage and water content ( p<0.05 , p<0.01 , respectively ) in different eight rats . - pubmed
To date , 7 patients have been reported with clinical symptoms suggesting a neurodegenerative disease . - pubmed
At birth , the male patient suffered from mild perinatal asphyxia due to meconium aspiration . - pubmed
Evaluating a new strategy for prophylaxis to prevent Pneumocystis carinii pneumonia in HIV - exposed infants in Thailand . - pubmed
METHODS : HIV - infected women were offered trimethoprim - sulfamethoxazole for PCP prophylaxis for their children at 1 - 2 months of age . - pubmed
A 15 - year follow - up of a boy with pyridoxine ( vitamin B6)-dependent seizures with autism , breath holding , and severe mental retardation . - pubmed
Most patients with pyridoxine - dependent seizures require lifelong treatment with pyridoxine . - pubmed
We report a 15 - year - old boy with pyridoxine - dependent seizures , nonpyridoxine - dependent seizures , severe mental retardation , autistic disorder , aerophagia , breath holding , and self - injury . - pubmed
Is compensatory vasoconstrictor tone in the hindquarter vascular region induced by hemorrhage in conscious spontaneously hypertensive rats ? - pubmed
We investigated whether a compensatory vasoconstrictor action would be induced by a hypotensive intervention in the hindquarter vascular region of conscious spontaneously hypertensive rats ( SHRs ) . - pubmed
Healing index averaged 30 days / cm ( 27 days / cm when two patients with radial nerve palsy were excluded ) . - pubmed
Transient radial nerve palsy developed during lengthening in two patients , and lengthening was discontinued . - pubmed
Symptoms of radial nerve palsy resolved completely in both patients , but one patient required an additional surgery to explore the radial nerve for persistent paresthesia of the forearm . - pubmed
Bilateral humeral lengthening was very effective for improving function and overall proportion in patients with achondroplasia . - pubmed
Biological characteristics and chemosensitivity profile of four human anaplastic thyroid carcinoma cell lines . - pubmed
The xenotransplantation of the lines in athymic nude mice produced tumors with a histology similar to the original tumors . - pubmed
We have studied 34 individuals in a large 84 - member four - generation central Illinois family with autosomal dominant Charcot - Marie - Tooth and deafness . - pubmed
Audiological evaluation revealed both auditory neuropathy and cochlear involvement in affected individuals . - pubmed
Another individual died at the age of 3 months from hypotonia later attributed to CMT . - pubmed
These results raise an important additional concern for the health consequences of nicotine abuse and open new insight on the possible neural mechanisms of tobacco addiction . - pubmed
Safety of abacavir therapy after temporary interruptions in patients without hypersensitivity reactions to the drug . - pubmed
The efficacy of Liposem , a polyherbal formulation , as an antioxidant and hypolipidaemic drug was evaluated in diet induced hyperlipidaemia in rats . - pubmed
The hypolipidaemic effect was assessed by serum lipid profile in dietary hyperlipidaemic rats and found to have decreased dose dependently in all the four different concentrations of administration ( 100 , 200 , 300 and 400 mg / kg body wt ) . - pubmed
This is a retrospective study of 276 patients consisting of 157 active and 119 reactive patients of borderline leprosy . - pubmed
Similar effects in humans may contribute to the increased incidence of psychiatric illness in individuals exposed to early life adversity . - pubmed
Comparison of quality of life and arm complaints after axillary lymph node dissection vs sentinel lymph node biopsy in breast cancer patients . - pubmed
The sentinel lymph node biopsy ( SLNB ) represents a minimal invasive surgical method for axillary staging in patients with primary breast cancer . - pubmed
Arm / shoulder pain was reported in 36 % of patients after SLNB in comparison to 68 % receiving axillary lymph node dissection ( ALND ) , and ' numbness ' was reported only in 4 % of patients in the SLNB group vs 19.3 % after ALND . - pubmed
Effect of pregnancy and lactation on granuloma tissue formation and joint permeability in rats . - pubmed
MRI plays a strategic role in patient care for initial evaluation and treatment planning in patients with ovarian cancer . - pubmed
[ Clinical factors associated with response to biofeedback therapy for patients with chronic constipation ] . - pubmed
METHODS : Biofeedback treatment was performed in 114 patients with constipation . - pubmed
Using prognostic factors , we may be able to evaluate the patterns of pelvic floor dysfunction and responsiveness of biofeedback therapy for the patients with constipation . - pubmed
Changes in intraocular pressure ( IOP ) elicited by a Valsalva manoeuvre were studied in 11 male patients ( mean age 39.8 years ) suffering from episodic cluster headache ( CH ) , and 12 healthy male controls ( mean age 39.9 years ) . - pubmed
It has been reported that the oral administration of TAS-102 increases the AUC of FTD in rodents and monkeys in different manners . - pubmed
Based on this modeling , we were able to quantitatively explain the TPI dose - dependent enhancement of AUC of FTD in monkeys , while little increase was observed in rats . - pubmed
The differences in in vivo erythropoietic activity among glycosylation analogs were more evident with increased time following administration in exhypoxic polycythemic mice . - pubmed
Neosporosis in a young dog presenting with dermatitis and neuromuscular signs . - pubmed
A 16 - week - old , male boxer dog developed multifocal nodular dermatitis followed by rapidly progressive and fatal neuromuscular disease . - pubmed
Serology suggested active infection with Neospora caninum . - pubmed
However , hearing loss and exposure to various environmental sounds can lead to changes in multiple organ systems , making what laboratory animals hear of consequence for researchers beyond those solely interested in hearing . - pubmed
For example , several inbred mouse strains commonly used in biomedical research ( e.g. - pubmed
Both researchers and laboratory animal facility personnel should be aware of both strain and species differences in hearing in order to minimize potentially confounding variables in their research and to aid in the interpretation of data . - pubmed
OBJECTIVES : To investigate whether or not impairment of HPV contributes to the hypoxemia associated with HVT and to evaluate the role of LTs in ventilator - induced lung injury . - pubmed
RESULTS : In wild - type mice , HVT , but not LVT , increased pulmonary vascular permeability and edema formation , impaired systemic oxygenation , and reduced survival . - pubmed
We present one patient with multiple upper tract carcinoma treated with percutaneous surgery and BCG . - pubmed
Twenty - five human cadavers were examined to study the anatomy of the closed vascular system between the retroauricular artery and the retroauricular vein in the skin on the posterior aspect of the auricle and the mastoid process . - pubmed
Our data show that RNAi results in stably inherited phenotypes and therefore represents an efficient tool for functional genomic studies in polyploid wheat . - pubmed
Comparison between serum and urinary sulphadimidine acetylation as predictors of isoniazid acetylator status in patients with pulmonary tuberculosis . - pubmed
The acetylator status of 200 pulmonary tuberculosis patients was determined by sulphadimidine ( SDM ) acetylation in ( 1 ) urine and ( 2 ) serum . - pubmed
SUBJECTS AND METHODS : Between 1998 and 2004 , 135 patients consecutively presenting with a parotid mass were prospectively enrolled into this study . - pubmed
Children who receive a diagnosis of bipolar disorder in community settings typically present with rapid fluctuations in mood and behavior , often associated with comorbid attention - deficit / hyperactivity disorder and disruptive behavior disorders . - pubmed
METHODS : We examined 45 male patients ( median age , 8 months ; range 3 - 28 ) with total epispadias and classic bladder exstrophy , combined with cryptorchidism . - pubmed
BACKGROUND : Documentation of superfoetation is extremely rare in humans . - pubmed
OBJECTIVE : The aim of the present study was to compare health - related quality of life ( HRQoL ) measures in euthymic patients with bipolar I and II disorder . - pubmed
METHOD : HRQoL was assessed using the Medical Outcomes Study 36 - Item Short - Form Health Survey ( SF-36 ) in 253 subjects recruited in 5 Italian centers : 90 patients with bipolar I disorder , 52 patients with bipolar II disorder , 61 subjects with RMD , and 50 healthy comparison individuals . - pubmed
CASE : A 26 - year - old , primiparous woman , 32 weeks pregnant , presented with a 1 - day history of pain in the upper abdomen . - pubmed
Initially the patient was managed conservatively on the suspicion of gastritis , but she did not respond . - pubmed
We demonstrate that this method can detect a single molecule of PicoGreen - stained mtDNA in intact DsRed2 - labeled mitochondrial particles isolated from human osteosarcoma 143B cells . - pubmed
Docetaxel monotherapy as second - line treatment for pretreated advanced non - small cell lung cancer patients . - pubmed
BACKGROUND : Second - line chemotherapy offers advanced non - small cell lung cancer ( NSCLC ) patients a small , but significant increase in survival . - pubmed
Hyperleukocytosis without other complications may not be an indication for adding cytotoxic therapy or steroids , nor for discontinuing arsenic trioxide therapy in children . - pubmed
Burn patients over the age of 60 are at a greater risk for developing pulmonary complications than younger patients . - pubmed
At 6 or 24 h after receiving sham or 15 % total body surface area scald injury , lungs from young and aged mice were analyzed for leukocyte content by histological examination and immunostaining . - pubmed
At 24 h , in contrast , neutrophils returned to sham levels in the lungs of young , burn - injured mice ( P<0.05 ) but did not change in the lungs of aged , burn - injured mice . - pubmed
Changes in circulation of B and non - B HIV strains : spotlight on a reference centre for infectious diseases in Northern Italy . - pubmed
In the period 1980 - -1982 , new infections were entirely caused by HIV-1 subtype B strains and were all diagnosed in injection drug users , 88.9 % of whom were males . - pubmed
In conclusion , a picture of the changing scenario of circulating HIV types and subtypes in a reference Infectious Diseases centre in Northern Italy over the past 26 years is provided . - pubmed
A progressive modification in risk factors for HIV infection and a significant increase in the frequency of non - B HIV strains were observed . - pubmed
A 43 - year - old man presented with a 2 - month history of left upper lobectomy due to an atypical lung carcinoid tumor . - pubmed
Malaria is currently highly prevalent and restricted to the north of Brazil , and its dynamics are severely affected by human environmental changes , such as the large dam construction recently approved by the Brazilian Government in Rondonia . - pubmed
As HH is a major risk factor for brain injury and subsequent neurodevelopment handicap , the identification , rapid diagnosis and prompt management of patients with HH is essential if brain damage is to be avoided . - pubmed
Advances in molecular genetics , radiological imaging techniques ( such as fluorine-18 L-3 , 4 - dihydroxyphenylalanine positron emission tomography ( ( 18F ) DOPA - PET ) scanning ) and laparoscopic surgery have completely changed the clinical approach to infants with the severe congenital forms of HH . - pubmed
The introduction of Rituximab has greatly improved therapeutic options for patients with B - cell non - Hodgkin lymphoma ( B - NHL ) . - pubmed
However , a substantial fraction of patients with aggressive B - NHL fails first - line therapy , and most patients with relapsing indolent B - NHL eventually acquire Rituximab resistance . - pubmed
METHODS : A total of 108 patients who had HCC were classified according to these systems . - pubmed
Endoscopic biliary drainage for choledocholithiasis in a patient with aplastic anemia before hematological engraftment after allogeneic transplantation . - pubmed
A 30 - year - old man was diagnosed with severe aplastic anemia in 1997 . - pubmed
One option is based on the vaccination of cancer patients with autologous inactivated intact tumor cells . - pubmed
BACKGROUND : Affecting the core functional microbiome , peculiar high level taxonomic unbalances of the human intestinal microbiota have been recently associated with specific diseases , such as obesity , inflammatory bowel diseases , and intestinal inflammation . - pubmed
Trichinella infection was detected in 1 puma [ 2 larvae per gram ( LPG ) ] , 3 wild boars ( 8 - 420 LPG ) , 3 armadillos ( 0.04 - 0.08 LPG ) , and 9 rats ( 0.1 to 150 LPG ) . - pubmed
The presence of Trichinella infection among wild animal populations suggests a sylvatic cycle of transmission in Argentina , which can serve as a reservoir for humans and domestic animals . - pubmed
A total of 1337 hepatitis B cases ( including 38 cases of co - infection with HCV ) were reported in Poland in 2008 , with incidence rate 3.51 per 100,000 population . - pubmed
Compelling evidence has accumulated that histologic assessment of infiltration patterns of different host immune response components in non - small cell lung cancer specimens helps identify different prognostic patient subgroups . - pubmed
CONCLUSION : Because apathy has not yet been found to relate to meaningful patient outcomes , and it appears that other factors such as depression and cognition are more strongly related to quality of life than apathy , there is not enough evidence to conclude that apathy is a clinically meaningful syndrome in PD . - pubmed
Characterization of ex vivo expanded tumor infiltrating lymphocytes from patients with malignant melanoma for clinical application . - pubmed
Clinical trials of adoptive transfer of autologous tumor infiltrating lymphocytes ( TILs ) to patients with advanced malignant melanoma have shown remarkable results with objective clinical responses in 50 % of the treated patients . - pubmed
When autologous tumor was available , TILs showed specific activity in all patients tested . - pubmed
Comparison of a commercially available repetitive - element PCR system ( DiversiLab ) with PCR ribotyping for typing of clostridium difficile strains . - pubmed
METHOD : Between October 2008 and December 2009 , 140 patients with ovarian cysts undergoing laparoscopic cystectomy at Peking Union Medical Hospital were enrolled : 74 had ovarian endometrioma with no preoperative hormonal therapy ( group A ) , 40 had ovarian endometrioma pretreated with GnRHa ( group B ) , and 26 had non - endometriotic cysts ( group C ) . - pubmed
In young rats , the sustained pressor response was associated with increased indices of renal vascular resistance , glomerulosclerosis and tubulointerstitial damage as well as with a moderate inflammatory response . - pubmed
In adult rats , renal pathology and inflammation was significantly less than in young rats and was reversible . - pubmed
Two patients developed ventricular fibrillation during hypothermia , both had an acute myocardial infarction . - pubmed
We did not find increased risk for bleeding complications in patients with double platelet inhibition after PCI ( 14.3 % compared to 9.5 % without PCI , p=0.63 ) compared to those without PCI . - pubmed
CONCLUSIONS : Under strict clinical and laboratory parameter control , induced mild therapeutic hypothermia can be applied to most patients after out - of - hospital cardiac arrest with no increased risk for arrhythmias despite significant electrocardiographic changes . - pubmed
The validity study was performed on data from 201 patients with acute stroke . - pubmed
Fifty patients with stroke and acquired brain injury were recruited to examine intertester and test - retest reliability . - pubmed
In a pilot study , contrast - enhanced whole - heart coronary MRI was also acquired in four patients with suspected coronary artery disease with 3 - fold acceleration . - pubmed
Hemorrhagic enterocolitis and death in two felines ( Panthera tigris altaica and Panthera leo ) associated with Clostridium perfringens type A. - pubmed
Severe hemorrhagic enterocolitis was observed in a Siberian tiger ( Panthera tigris altaica ) and a lion ( Panthera leo ) . - pubmed
High agreement of routine cytopathology and immunocytochemistry in canine lymphomas . - pubmed
The study was performed on cytological samples of 70 canine lymphomas subtyped on the basis of the updated Kiel classification system . - pubmed
Bone resorption markers , Urinary hydroxyproline excretion was significantly increased ( p<0.001 ) in postmenopausal women . - pubmed
The results from this study suggest that simple , easy , common biochemical markers can still be used to assess the bone turnover in postmenopausal women and hence their risk of developing osteoporosis and fractures . - pubmed
A novel type of selective immunoglobulin m deficiency in a patient with autoimmune liver cirrhosis with recurrent hepatocellular carcinoma : a case report and review of the literature . - pubmed
Tests for diagnosis , specially for screening HIV antibodies , are now fully automated ; in the same way , tests for monitoring HIV viral load ( HIV RNA copies / ml of plasma ) , which is used for monitoring infection and response to antiretroviral treatment , are also fully automated ; however , resistance testing , tropism determination and minor variant detection , which are used to make decisions for changing antiretroviral treatment regimens in patients failing therapy , still remain highly laborious and time consuming . - pubmed
A case of 42 - year - old man with post - traumatic right hepatic artery pseudoaneurysm successfully treated by endovascular embolization with histoacrylate glue is presented . - pubmed
METHODS : The data of 123 consecutive AF patients ( 74 paroxysmal and 49 persistent AF ) who underwent RFCA between April 2009 and December 2010 in our department were retrospectively analyzed . - pubmed
The patients were divided into recurrence group and no recurrence group . - pubmed
The ratio of patients with HATCH & gt;= 2 in recurrence group was higher than in non - recurrence group [ 23.3 % ( 10/43 ) vs. 8.8 % ( 7/80 ) , P & lt ; 0.01 ] . - pubmed
Cumulative non - recurrence rate of patients with HATCH score & gt;= 2 was lower than patients with HATCH score = 0 and 1 ( P & lt ; 0.05 ) . - pubmed
BACKGROUND : Some patients with typical ( heartburn / regurgitation ) symptoms of gastroesophageal reflux disease ( GERD ) are refractory to proton pump inhibitor ( PPI ) therapy . - pubmed
METHODS : Forty - four consecutive GERD patients with heartburn / regurgitation refractory to high - dose PPI therapy entered a 3 - year outcome assessment following robot - assisted laparoscopic fundoplication . - pubmed
Postoperatively , heartburn / regurgitation recurred in 3 patients ; abnormal impedance - pH findings were found in two of them , and they responded to PPI therapy . - pubmed
CONCLUSIONS : Normal reflux parameters and persistent symptom remission at 3 - year follow - up can be achieved with laparoscopic fundoplication in the majority of patients with PPI - refractory GERD as diagnosed by impedance - pH monitoring . - pubmed
Autologous rat BPCs seeded on various scaffolds were transplanted into critical - size calvarial defects . - pubmed
We aimed to asses whether there was any evidence for a modified radical neck dissection over a selective neck dissection by looking at the extent to which DTC metastases to levels I and V. We performed a review of the current literature including adult and paediatric patients who underwent a lateral neck dissection for metastatic DTC . - pubmed
The incidence of level V metastases during routine level V dissection in patients with DTC is 20 % and the incidence of level I metastases during routine level I dissection in patients with DTC is 8 % . - pubmed
Irreversible MAOIs have the potential to treat the most challenging mood disorder patients including those with treatment - resistant depression , atypical depression and bipolar depression . - pubmed
Exercise rehabilitation is beneficial and has become a standard of care in patients with systolic heart failure and chronic obstructive pulmonary disease . - pubmed
In recent years , several small - scale studies have demonstrated that closely supervised and monitored exercise training programs may have potential benefits in the management of stable PAH patients , improving exercise capacity and quality of life , with an acceptable low risk of adverse events in the studied populations . - pubmed
This review describes the emerging clinical data supporting the efficacy and safety of exercise training in PAH patients . - pubmed
Whole genome sequencing and phylogenetic analysis of West Nile virus lineage 1 and lineage 2 from human cases of infection , Italy , August 2013 . - pubmed
A human outbreak of West Nile virus ( WNV ) infection caused by WNV lineage 2 is ongoing in northern Italy . - pubmed
Analysis of six WNV genome sequences obtained from clinical specimens demonstrated similarities with strains circulating in central Europe and Greece and the presence of unique amino acid changes that identify a new viral strain . - pubmed
BACKGROUND : Early age at infection with hepatitis B virus ( HBV ) increases the risk of chronic HBV infection . - pubmed
PATIENTS AND METHODS : Peripheral blood samples were collected from 81 patients with colorectal cancer , 16 with gastric cancer and 38 healthy blood donors , as controls . - pubmed
CONCLUSION : Multiplex - PCR - based detection of circulating tumor cells could serve as a useful tool for the diagnosis , and monitoring of patients with colorectal and gastric cancer . - pubmed
Relationship between angina pectoris and outcomes in patients with heart failure and reduced ejection fraction : an analysis of the Controlled Rosuvastatin Multinational Trial in Heart Failure ( CORONA ) . - pubmed
METHODS AND RESULTS : Four thousand , eight hundred and seventy - eight patients were divided into three categories : no history of angina and no chest pain at baseline ( Group A ; n = 1240 ) , past history of angina but no chest pain at baseline ( Group B ; n = 1353 ) and both a history of angina and chest pain at baseline ( Group C ; n = 2285 ) . - pubmed
CONCLUSION : Patients with HF - REF and ongoing angina are at an increased risk of acute coronary syndrome and HF hospitalization . - pubmed
Migraine was ascertained in 129 ( 16 % ) of 787 adolescents at age 18 years . - pubmed
Of the 22 adolescents , 14 ( 64 % ) had migraine without aura and eight ( 36 % ) had migraine with aura . - pubmed
Infants with colic had an almost three - fold risk ( risk ratio 2.8 , 95 % confidence interval 1.2 - 6.5 ) for adolescent migraine without aura , but no increased risk for migraine with aura ( 0.8 , 0.3 - 2.2 ) . - pubmed
GOAL : The goal of the research was to determine the efficacy of a fixed combination of tramadol and paracetamol ( acetaminophen ) in the treatment of pain of patients with the advanced stage of cancer . - pubmed
A total of 353 patients who were treated with a fixed combination of tramadol and acetaminophen ( 37.5 mg and 325 mg ) at the initial dosage 3x1 tablet ( 112.5 mg tramadol and 975 mg acetaminophen ) for pain intensity 4 , up to 4x2 tablets ( 300 mg of tramadol and 2600 mg paracetamol ) for pain intensity 7 and 8 . - pubmed
If the patient during previous day has two or more pain episodes that required a " rescue dose " of tramadol , increased was the dose of fixed combination tramadol and acetaminophen to a maximum of 8 tablets daily ( 300 mg of tramadol and 2600 mg paracetamol ) . - pubmed
Side effects , in the treatment of pain with a fixed combination tramadol and acetaminophen , were found in 29.18 % of patients , with a predominance of nausea and vomiting . - pubmed
A novel locus on canine chromosome 13 is associated with cataract in the Australian Shepherd breed of domestic dog . - pubmed
Hereditary cataract is a common ocular disorder in the purebred dog population and is a leading cause of visual impairment and blindness in dogs . - pubmed
Cataract cases were defined as dogs with bilateral posterior cataracts , or bilateral nuclear cataracts . - pubmed
Using 15 bilateral posterior polar cataract cases and 68 controls , we identified a genome - wide statistical association for cataracts in the Australian Shepherd on canine chromosome 13 at 46.4 Mb ( P value : 1.5 x 10(-7 ) ) . - pubmed
Both Staphylococcus aureus and Staphylococcus epidermidis can form biofilms on natural surfaces or abiotic surfaces , such as medical implants , resulting in biofilm - associated diseases that are refractory to antibiotic treatment . - pubmed
Delirium is a robust predictor of morbidity and mortality among critically ill patients treated in the cardiac intensive care unit . - pubmed
Among 590 patients included , the prevalence of CICU delirium was 20.3 % . - pubmed
Three of these inhibitors , suberoylanilide hydroxamic acid ( SAHA ; vorinostat ( ) ) , romidepsin ( Istodax ( ) ) and belinostat ( Beleodaq ( ) ) , are clinically approved for the treatment of T - cell lymphoma , while the fourth , panobinostat , has recently been approved for combination therapy use in certain patients with multiple myeloma . - pubmed
The compounds were found to have some selectivity for malaria parasites compared with mammalian cells , but were not selective for trypanosome parasites versus mammalian cells . - pubmed
Medial retropharyngeal lymph node ( MRLN ) mass lesions are a common cause of cranial cervical masses in dogs and cats , and are predominantly due to metastatic neoplasia , primary neoplasia , or inflammatory lymphadenitis . - pubmed
A total of 31 patients were sampled , with 15 in the inflammatory lymphadenitis group and 16 in the neoplasia group . - pubmed
Patients with inflammatory lymphadenitis were more likely to be younger and present with lethargy ( P = 0.001 ) , pyrexia ( P = 0.000 ) , and neck pain ( P = 0.006 ) . - pubmed
Patients with inflammatory lymphadenitis were also more likely to have a leukocystosis ( P = 0.02 ) and segmental neutrophilia ( P = 0.001 ) . - pubmed
A randomized comparative trial with 104 healthy premenopausal women with overweight / obesity was conducted in a university setting . - pubmed
CONCLUSION : Using both office BP and HBPM this group of Thai patient with essential hypertension responded well to Losartan and Generic Losartan . - pubmed
They studied 301 patients with moderate ischemic mitral regurgitation ( IMR ) undergoing coronary artery bypass grafting ( CABG ) with or without mitral repair with the primary end - point of change in left ventricular end - diastolic volume index ( LVEDVI ) at one year and multiple clinical and echocardiographic secondary endpoints . - pubmed
Stabilization of Tnf mRNA and other cytokine transcripts in TTP - deficient mice results in the development of a profound , chronic inflammatory syndrome characterized by polyarticular arthritis , dermatitis , myeloid hyperplasia , and autoimmunity . - pubmed
The aims of this study were to determine the prognostic implication of UMI in patients with stable suspected coronary artery disease ( CAD ) and to investigate the associations of UMI with the presence of CAD . - pubmed
For each patient with UMI , the stenosis grade of the coronary branch supplying the infarcted area was determined . - pubmed
UMIs were present in 25 % of the patients and 67 % of the UMIs were located in an area supplied by a coronary artery with a stenosis grade & gt;=70 % . - pubmed
Cohort 2 consisted of 171 subjects including patients with Alzheimer disease and mild cognitive impairment and healthy volunteers . - pubmed
Antifibrinolytics ( lysine analogues ) for the prevention of bleeding in people with haematological disorders . - pubmed
BACKGROUND : People with haematological disorders are frequently at risk of severe or life - threatening bleeding as a result of thrombocytopenia ( reduced platelet count ) . - pubmed
METHODS : Forty - three mCRC patients who received cetuximab or panitumumab between April 2012 and December 2015 were the subjects of the present study . - pubmed
All patients were pretreated with oral minocycline in combination with skin treatment using moisturizer for prevention of skin rash . - pubmed
ORR was significantly higher in patients with hypomagnesemia than in those without it ( 71.4 vs 34.5 % , P = 0.048 ) . - pubmed
Median TTF tended to be longer , though not significantly , in patients with hypomagnesemia than in those without it . - pubmed
Histopathology of the filum terminale in children with and without tethered cord syndrome with attention to the elastic tissue within the filum . - pubmed
PURPOSE : To compare histologically transected fila from pediatric patients with tethered cord syndrome ( TCS ) , with and without a low conus , with controls , focusing on collagenous and elastic tissue . - pubmed
METHODS : Thirty fila from patients with TCS , including 5 where minimal cautery was used prior to filum section , were compared with fila from 27 pediatric cadavers without TCS ( controls ) . - pubmed
Resection guidelines that include a borderline resectable group , as well as advancements in neoadjuvant chemotherapy and radiation that improve resectability of locally advanced disease , may improve outcomes for patients with more invasive disease . - pubmed
Multi - agent chemotherapy regimens fluorouracil , leucovorin , irinotecan , and oxaliplatin ( FOLFIRINOX ) and nab - paclitaxel with gemcitabine improved response rates and survival in metastatic pancreatic cancer and are now being used in earlier stages for patients with localized potentially resectable and unresectable disease , with goals of downstaging tumors to allow margin - negative resection and reducing systemic recurrence . - pubmed
Patient selection for optimal treatment designation is currently provided by multidisciplinary tumor boards , but biomarker discovery , in blood , tumors , or through novel imaging , is an area of intense research . - pubmed
Results to date suggest that some patients with unresectable disease at the outset have survival rates as good as those with initially resectable disease if able to undergo surgical resection . - pubmed
Long - term follow - up and improved clinical trials options are needed to determine optimal treatment modalities for patients with localized pancreatic cancer . - pubmed
We describe a case of successful stenting of radio induced chronic occlusion of the right CCA in a 41 - year - old patient with neurological deterioration and minor stroke due to cerebral hypoperfusion caused by concomitant bilateral arterial occlusions . - pubmed
Here we studied a top QTP predator , the saker falcon , and analysed how the transcriptome has become modified to cope with the stresses of hypoxia and hypothermia . - pubmed
We did a review , restricted only to human studies , of transparent scientific articles and sample surveys carried out and published in the period between 2001 and 2016 based on the keywords : age , aging , physical activity , physical abilities , cognitive abilities , memory and Alzheimer ' s disease . - pubmed
ANIMALS : Eighty client - owned anemic , 72 donor , and 7 control dogs . - pubmed
All 126 pretransfusion cross - match results for the 80 anemic recipients were compatible , but 54 dogs died or were lost to follow up . - pubmed
Nivolumab improves survival for patients with advanced lung cancer . - pubmed
strains were isolated and characterized from these patients at different time points during and after ICU hospitalization , including E. - pubmed
MATERIAL AND METHODS : The records of 46 patients treated for distal tibia physeal fractures between 2003 and 2013 were reviewed . - pubmed
MATERIALS AND METHODS : We used a rat sciatic nerve injury model in which we completely transected and repaired the left sciatic nerve to evaluate the efficacy of PEG fusion over a span of 12 weeks . - pubmed
Thus , the use of beta - blockers may have beneficial effects on the treatment of myocardial fibrosis in patients with heart failure . - pubmed
Durable Resolution of Severe Psoriasis in a Patient Treated with Pentostatin for Hairy Cell Leukemia : A Case Report . - pubmed
CASE REPORT : Here , we report the case of a 43 - year - old patient with a history of extensive psoriasis who later developed HCL . - pubmed
RESULTS : The patient had achieved complete remission of both psoriasis and HCL after receiving intravenous infusions of pentostatin . - pubmed
It is worth noting that cladribine has already been reported to treat plaque psoriasis lesions in two patients with HCL and in a third patient with gastric marginal zone B cell lymphoma [ 1 ] . - pubmed
CONCLUSION : We believe that adenosine analogues constitute a promising therapeutic option for moderate to severe psoriasis , especially for severe and refractory psoriasis , as well as for patients with adjacent lymphoid malignancies . - pubmed
Material and Method : Patients with TMJ ankylosis ( 8 males , 2 females ) underwent release of the ankylosed joint by the senior author , between June 2013 and Novemeber 2015 . - pubmed
After reconstruction of temporomandibular joint with sternoclavicular graft in the growing child there was a significant increase in the growth of mandible which was stunned due to ankylosis . - pubmed
30 of these women have been enrolled in the basic group including children with congenital abnormalities ( CA ) . - pubmed
More than 60 % of patients with a PSAdt of less than or equal to 6 months had a positive F - FCH PET / CT scan for OMD . - pubmed
BACKGROUND : Patients with early stage tongue cancer do not frequently complain of tongue pain . - pubmed
Meniscal allograft transplantation has been used successfully to treat patients with postmeniscectomy syndrome , and there is early laboratory and radiographic evidence hinting at a potential prophylactic role in preventing joint degeneration . - pubmed
Transient Abnormalities in Masking Tuning Curve in Early Progressive Hearing Loss Mouse Model . - pubmed
A total of 90 outpatients of our hospital with onychomycosis were randomised into three treatment groups : ( 1 ) standard itraconazole pulse therapy ( 200 mg twice per day , 1 week each month for three pulses ) ; ( 2 ) long - term pulse therapy ( 200 mg twice per day , 1 week each month for six pulses ) ; ( 3 ) low - dose and long - term pulse therapy ( 200 mg / d , 1 week per month for six pulses ) and were followed up for 15 months . - pubmed
Escherichia coli chromosome - based T7 - dependent constitutive overexpression system and its application to generating a phenylalanine producing strain . - pubmed
Integration of synthetic pathway genes into the Escherichia coli chromosome enables generation of a plasmid - free strain that is stable and useful for industrial applications . - pubmed
The constructed overexpression system , a " chromosome - based T7 - dependent constitutive overexpression system " , was applied in a metabolic engineering study to generate a plasmid - free and inducer - free phenylalanine producing strain of E. - pubmed
BACKGROUND / PURPOSE : Lymphedema surgery , when integrated into a comprehensive lymphedema treatment program for patients , can provide effective and long - term improvements that non - surgical management alone can not achieve . - pubmed
Surgical treatments should not be seen as a " quick fix " , and should be pursued in the framework of continuing lymphedema therapy and treatment to optimize each patient 's outcome . - pubmed
Downexpression of miR-133b positively correlates with advanced clinicopathological characteristics and shorter bone metastasis - free survival in PCa patients . - pubmed
Method : A retrospective analysis of 50 patients with Eustachian tube dysfunction diagnosed . - pubmed
Metabolomic fingerprint of coronary blood in STEMI patients depends on the ischemic time and inflammatory state . - pubmed
In this study we investigated whether the metabolomic analysis could identify a specific fingerprint of coronary blood collected during primary PCI in STEMI patients . - pubmed
Given its more convenient regimen and our results , it seems justified to use azithromycin as the first - line treatment for patients with preterm premature rupture of membranes . - pubmed
Mycobacterium abscessus felon complicated with osteomyelitis : not an ordinary nail salon visit . - pubmed
Mycobacterium abscessus is an environmental organism that has been implicated in pulmonary and extrapulmonary infections . - pubmed
Pressure pain sensitivity in patients with traumatic first - time and recurrent anterior shoulder dislocation : a cross - sectional analysis . - pubmed
Methods This was a cross - sectional analysis of baseline data from a randomized controlled trial including 34 patients with first - time ASD [ 82 % male , mean ( SD ) age 26 ( 7 ) years ] and 22 patients with recurrent ASD [ 96 % male , mean ( SD ) age 25 ( 5 ) years ] . - pubmed
Patients were assessed as follows : ( 1 ) assessment of local and distant pressure pain sensitivity evaluated by pressure pain thresholds ( PPTs ) using a handheld algometer on mm . - pubmed
PURPOSE : The aim of this study was to assess the functional and clinical results of patients who underwent ACL reconstruction surgery and were divided into subpopulations related to ACL - associated lesions and focused on ALL - associated lesion . - pubmed
In 42 patients out of 62 ( 68 % ) , ALL lesion was evident . - pubmed
RESULTS : The overall re - injury rate in our cohort of patients was 4.8 % with a smaller but not a significant difference between the two groups . - pubmed
CONCLUSION : The additional ALL reconstruction / repair surgery should always be considered in patients with evident ALL tear at the preoperative MRI . - pubmed
Evaluation of Neospora caninum serodiagnostic antigens for bovine neosporosis . - pubmed
Abortion and reproductive failure caused by Neospora caninum infection has a dramatic negative economic impact on the cattle industry . - pubmed
caninum antigens in relation to abortion in cattle . - pubmed
METHODS : 60 laryngectomized patients with VP and 30 controls were included in the study . - pubmed
RESULTS : A total of 7198 ESs were deployed endoscopically in hospitalized patients with dysphagia . - pubmed
CONCLUSION : In the preceding decade , ES placement for hospitalized patients with dysphagia has increased , driven largely by an over 8 - fold rise in stent placement for benign indications . - pubmed
Polycystic ovary syndrome ( PCOS ) in adolescent girls is usually related to hepato - visceral fat excess and insulin resistance , and associates with comorbidities such as type 2 diabetes . - pubmed
RESEARCH DESIGN AND METHODS : We studied 51 adolescent patients with PCOS and 21 age - matched healthy controls . - pubmed
Thirty - one adolescent patients with PCOS under SPIOMET or oral contraception - based treatment were also studied . - pubmed
Human immunodeficiency virus type 1 ( HIV-1 ) establishes lifelong infections in humans , a process that relies on its ability to thwart innate and adaptive immune defenses of the host . - pubmed
IMPORTANCE People living with HIV can experience accelerated aging and the development of neurological disorders . - pubmed
The purpose of this study was to investigate the cardioprotection offered by the iron - chelating agent deferiprone ( DFP ) in a porcine AMI model by evaluating hemorrhage neutralization and subsequent cardiac remodeling . - pubmed
Impaired follicular development and endocrine disorders in female rats by prepubertal exposure to toxic doses of cadmium . - pubmed
Chemoradiation in elderly patients with glioblastoma from the multi - institutional GBM - molRPA cohort : is short - course radiotherapy enough or is it a matter of selection ? - pubmed
BACKGROUND : The optimal radiotherapy regimen in elderly patients with glioblastoma treated by chemoradiation needs to be addressed . - pubmed
HBV+ cohort were younger ( p<0.001 ) but just as likely to have diabetes , be on dialysis , and have similar smoking status compared to HBV- cohort . - pubmed
As a special subpopulation , pregnant women are more susceptible to nanoparticle ( NP)-induced toxicity . - pubmed
Early diagnosis and genetic testing of FH suspects is critical for improved prognosis of affected individuals as lipid lowering treatments are effective in preventing CHD related morbidity and mortality . - pubmed
Methods The study included 311 patients with invasive BC diagnosed at the Department of Pathology , School of Medicine in Sarajevo , Bosnia and Herzegovina , during the period 2015 - 2019 . - pubmed
OBJECTIVE : To explore the genetic basis for a child with ichthyosis . - pubmed
Patients undergoing PD for biliary , duodenal or pancreatic diseases are randomly assigned to the TXA or placebo group . - pubmed
Patient characteristics , immediate versus delayed reconstruction , type of flap used , indication for secondary augmentation as well as perioperative and postoperative complication including flap or implant loss were reviewed and analyzed . - pubmed
Postoperative surgical site infection occurred in a total of 4 patients ( 17 % ) with 3 patients requiring explantation of a total of 4 implants . - pubmed
In a subgroup of patients affected with novel Coronavirus disease ( COVID-19 ) , tocilizumab has also increased the survival rate . - pubmed
We present the case of a 31 - years - old Caucasian patient who experienced an almost asymptomatic Severe Acute Respiratory Syndrome Coronavirus ( SARS - CoV-2 ) infection during treatment with tocilizumab , which was continued due to the very high risk of relapses of the patient . - pubmed
This study aims to establish an ELISA kit specifically for detecting UHp in urine samples of patients with diabetes and DKD . - pubmed
This kit was used to detect UHp in 246 healthy individuals and 83 patients with type 2 diabetes ( T2D ) . - pubmed
METHODS : Data of adult patients with RA , PsA or axSpA who had received reference etanercept were retrospectively analysed . - pubmed
RESULTS : Data of 84 patients were available ( 44 RA , 25 axSpA and 15 PsA patients ) , of whom 24 had been informed about the planned switch ( 28.5 % ) . - pubmed
Seven patients were lost to follow - up , and six patients discontinued due to inefficacy or ADE . - pubmed
RESULTS : Eleven of 199 patients with GC who achieved ypT0N0 status after NAC were classified as the pCR group in this study . - pubmed
Effectiveness of Hearing Aid Treatment in Patients with Chronic Tinnitus : Subscale Evaluations Using the Tinnitus Functional Index and Factor Analysis . - pubmed
A total of 21 patients with chronic tinnitus were included . - pubmed
A method is described for comparing narcotic analgesics and adjuvants in patients with terminal cancer . - pubmed
Egg production dropped after hens were inoculated with fowlpox virus originally isolated from a natural mild infection . - pubmed
[ 3H ] GABA binding in brains from Huntington ' s chorea patients : altered regulation by phospholipids ? - pubmed
Binding sites for tritum - labeled gamma - aminobutyric acid ( GABA ) in cerebellar cortex of Huntington ' s chorea patients have an increased affinity but unaltered maximum capacity as compared to binding sites in tissue from control patients . - pubmed
Limb - saving resection has become a valid alternative to amputation in carefully selected patients with bone tumors . - pubmed
The samples were obtained from 12 patients with suspected intracranial disease . - pubmed
Prognostic significance of lymph node histology in patients with squamous cell carcinoma of the larynx , pharynx , or oral cavity . - pubmed
Metastases occurred much more frequently in patients whose nodes showed immunologic activity than in those whose did not . - pubmed
X - ray therapy of selected odontogenic neoplasms in the dog . - pubmed
Macrophage function and host resistance against infection with Toxoplasma gondii . - pubmed
The role of macrophages on the course of an infection with Toxoplasma gondii has been examined . - pubmed
The functional blockade of macrophages by dextran sulfate or carbon particles did not result in a higher susceptibility of mice to the lethal primary infection with T. - pubmed
Thus in vivo macrophages apparently do not play an essential role as effector cells as they do in infections with other obligate intracellular infective organisms such as Listeria monocytogenes . - pubmed
gondii infection , since death occurred earlier in splenectomized mice than in control animals . - pubmed
Data are presented on the state of the intrahepatic blood flow and the absorption - excretory capacity of the liver in 221 patients with acute myocardial infarction . - pubmed
The agents were tested for cytotoxic activity against P388 mouse leukemia cells . - pubmed
None of the target molecules were as potent against Escherichia coli as they were against the tumor cells . - pubmed
To evaluate the efficacy of plasma perfusion as a liver - assistance system , 17 patients with hepatic failure were treated with a total 37 sessions of plasma perfusion and 43 sessions of plasma exchange . - pubmed
A case of human endocarditis due to Streptococcus suis in North America . - pubmed
We thus prospectively examined 275 children with epilepsy ; in particular , we analyzed the prognostic role of the EEG . - pubmed
In 107 children the anticonvulsive therapy was discontinued , leading to a relapse rate of 27 % . - pubmed
We reviewed scans from 500 patients who had screening CT examinations of the sinuses for preendoscopic evaluation of inflammatory sinonasal disease to better define an optimal imaging protocol . - pubmed
A 62 - year - old man with rheumatoid arthritis developed jaundice while taking piroxicam . - pubmed
The patient 's jaundice and all other liver function abnormalities normalized 4 months after he discontinued taking piroxicam . - pubmed
Glucose partitioning in the pregnant ewe : effects of undernutrition and exercise . - pubmed
Clinical manifestations of gastrocnemius hematoma in a 64 - year - old man with local swelling , pain and tenderness that was aggravated by passive dorsiflexion of the ankle joint , mimicked deep vein thrombosis . - pubmed
In experimental animals beta - blockers have been found to reduce spontaneous motor activity , to counteract isolation- , lesion- , stimulation- and amphetamine - induced hyperactivity , and to produce slow - wave and paradoxical sleep disturbances . - pubmed
[ Antibiotic - associated colitis and Clostridium difficile ] . - pubmed
Laser Doppler flowmetry ( LDF ) is a new and noninvasive technique for skin blood flow measurement and has been used pre - operatively in 25 patients undergoing amputation for vascular disease and in five normal controls . - pubmed
One patient had mild paresis of the lower extremities . - pubmed
Effect of cyclosporine on immunologically mediated diabetes in nonobese diabetic mice . - pubmed
Spontaneous diabetes in NOD mice has an immunologically mediated cause and is a T cell - dependent process . - pubmed
When diabetic NOD mice are grafted with cultured BALB / c islet tissue , the islet graft is destroyed by disease recurrence in the graft . - pubmed
Data presented here show that cyclosporine is ineffective in controlling disease recurrence in the islet graft transplanted to actively diabetic animals . - pubmed
Nine eyes of nine patients affected by retinal detachment with macular hole were treated with pneumoretinopexy and postoperative positioning . - pubmed
The prevention of postoperative pain in children who had undergone tonsillectomy was investigated in a double - blind trial . - pubmed
Lung biopsies from four children and two adults with idiopathic pulmonary haemosiderosis have been examined by transmission electron microscopy . - pubmed
The carrageenin rat paw edema was dose - dependently inhibited by i.v . - pubmed
In contrast , no antiinflammatory activity of desferrioxamine could be seen in rat adjuvant arthritis , a model of subacute and chronic inflammation . - pubmed
Magnetic resonance ( MR ) imaging of the cervical spine was employed in 18 patients with rheumatoid arthritis and suspected cervical involvement . - pubmed
Fifteen patients had symptoms referable to the cervical spine , and seven had neurologic deficits . - pubmed
Cervical radiographs were available for all patients ; bone erosion was evident in 14 , subluxation in 17 , and no abnormalities in one . - pubmed
MR imaging demonstrated indentation or abnormal signal in the caudal brain stem and/or cervical spinal cord in ten patients , including the seven with related neurologic deficits ; discrete indentation or distortion of the dura without visible morphologic effect on the underlying neuraxis was observed in five other patients . - pubmed
In all patients with neurologic symptoms , cord or brain - stem abnormalities were seen on MR images . - pubmed
MR imaging therefore appears to provide valuable information regarding the status of the spinal cord and dura in patients with rheumatoid arthritis . - pubmed
PISA -- a new noninvasive method for early detection and quantification of ischemia in hypertensive patients . - pubmed
This method was therefore used in 25 healthy individuals , 20 patients with documented ischemic heart disease and 50 hypertensive patients ( duration 1 - 6 years ) with no end - organ disease in order to determine if these patients have myocardial ischemia and/or infarction . - pubmed
All 20 patients with documented ischemic heart disease had phase variant signature and had high PISA index in two or more leads . - pubmed
Twenty - nine of the 50 hypertensive patients were found to have phase - variant ( abnormal ) PISA signatures and their PISA index was beyond the upper limit of normal PISA range ( mean + 3S.D. - pubmed
Recovery of VEP delay in patients with vitamin B12 deficiency . - pubmed
Two patients with a neurologic syndrome of vitamin B12 deficiency and delayed Visual Evoked Potentials are reported . - pubmed
[ Response of rat fetal adrenal glands to an aggression in different experimental conditions ; effect of nembutal ] . - pubmed
[ Effect of the house climate and hygiene on production and the incidence of respiratory and intestinal disorders in pig breeding ] . - pubmed
Amebic cellulocutaneous invasion by Naegleria aerobia with generalized visceral lesions after subcutaneous inoculation : an experimental study in guinea pigs . - pubmed
Data obtained from the naturally resistant rat that had been immunized with both the Belton - Strange protective antigen and live vaccine demonstrated the role of " toxins " in terminal anthrax . - pubmed
Facilitation and antagonism of kindled seizure development in the limbic system of the rat . - pubmed
To study the relative contribution of positive and negative transfer during the kindling of motor seizures , we electrically stimulated the septal area and entorhinal cortex in rats according to two different stimulation paradigms . - pubmed
Thirteen of 14 animals exhibited generalized convulsions from one site only . - pubmed
Eight patients who had facial nerve neuromas were examined , and the radiographic findings are reported . - pubmed
Radiologic imaging frequently permits a correct preoperative diagnosis and accurate definition of the extent of facial nerve neuromas , assessments that are important for proper patient management . - pubmed
Comparative enzyme - inducing effects of chlorpromazine and fluphenazine therapies in psychotic patients . - pubmed
Antipyrine elimination kinetics were measured in psychotic patients receiving either long - term chlorpromazine or fluphenazine decanoate therapy and in non - medicated control subjects . - pubmed
In addition , it is suggested that bovine cervical mucus could be developed as a possible substitute for human cervical mucus in cases of infertility due to deficient endogenous mucus . - pubmed
Appendico - vesical fistula and persistent urachus in a patient with hematuria . - pubmed
A 35 - year - old man had been treated with sulfamethizole on 6 occasions because of recurrent urinary tract infections . - pubmed
Dihydroergotoxine administration shortened the latency of allylglycine - and picrotoxin - induced convulsions in rats and increased the incidence of convulsions elicited by picrotoxin , i.e. - pubmed
A localized atheromatous plaque was induced in rabbits after transmural electrical stimulation of the carotid and a cholesterol - rich diet ( 1.33 % cholesterol ) for 4 weeks . - pubmed
During the experimental period , all rabbits showed similar weight gain , regardless of the treatment . - pubmed
Seventeen patients who received radioiodine ( 131I ) therapy for Graves ' hyperthyroidism had serial blood samples taken before therapy and after therapy for a period of at least 1 year . - pubmed
Seven patients were euthyroid , and four patients were hyperthyroid . - pubmed
Four patients out of 11 developed hypothyroidism and six of the 11 developed euthyroidism . - pubmed
A decrease in TBII was observed in three patients who developed hyperthyroidism . - pubmed
Of these , four developed hypothyroidism and three developed euthyroidism , whereas three of the four patients who had a marked decrease in TPOAb developed hyperthyroidism . - pubmed
Four mouse B16 melanoma subclones ( G3.15 , G3.5 , G3.12 and G3.26 ) exhibit progressively greater growth capacity in vitro and in vivo . - pubmed
Interest in tick - borne pathogens has been enhanced by the emergence of Lyme disease and , more recently , human and animal ehrlichioses . - pubmed
CONCLUSION : It appears that conservative treatments contributed to the decreased survival of older ovarian cancer patients . - pubmed
This case suggests that we must consider the presence of coronary vasospasm even in patients with clinically - supposed effort angina , to be possibly due to vasospasm occurring in anomalous coronary arteries . - pubmed
MRI findings in an individual at risk for familial Alzheimer ' s disease . - pubmed
Anthroponotic cutaneous leishmaniasis in Kabul , Afghanistan : the high susceptibility of Phlebotomus sergenti to Leishmania tropica . - pubmed
Causal relationship between occlusive lesions of the coronary artery and myocardial fibrosis in arteriosclerotic rabbits -- differences between cholesterol - fed and heritable hyperlipidemic rabbits . - pubmed
To investigate the causal relationship between lesions of either the proximal large or the distal small coronary arteries and myocardial fibrosis , the hearts and the aortas of 99 cholesterol - fed rabbits with either intermittent or continuous hyperlipidemia for 8 months or more , 44 Watanabe - heritable hyperlipidemic ( WHHL ) rabbits and 20 normal rabbits were studied histologically . - pubmed
The size and location of the myocardial fibrosis correlated closely with the almost completely occlusive distal small coronary artery which mainly consisted of macrophages , necrosis and calcification but did not correlate with the maximum % stenosis of the large proximal subepicardial coronary arteries in the cholesterol - fed - rabbits . - pubmed
Myocardial fibrosis and almost completely occlusive lesions of the distal small coronary arteries were very rare in the WHHL rabbits , and the maximum % stenosis of the proximal coronary artery and aortic lesions in the WHHL rabbits tended to be greater than those in the cholesterol - fed rabbits . - pubmed
Thus , we are still not certain as to whether or not , the organic stenosis of the subepicardial coronary artery is responsible for myocardial fibrosis in WHHL - rabbits . - pubmed
In conclusion , a causal relationship was observed between myocardial fibrosis and the occlusive lesions of the distal small coronary arteries in cholesterol - fed rabbits , while the arteriosclerotic lesions of the small coronary artery in cholesterol - fed rabbits completely differed from those observed in WHHL - rabbit . - pubmed
Enhancement of gene therapy specificity for diffuse colon carcinoma liver metastases with recombinant herpes simplex virus . - pubmed
OBJECTIVE : The authors determined whether a recombinant herpes simplex virus ( HSV ) vector could destroy human colon carcinoma cells in vitro and whether the vector would selectively replicate in colon carcinoma liver metastases but not surrounding hepatocytes in vivo . - pubmed
Further investigation of HSV - based vectors as oncolytic agents for liver metastases is warranted . - pubmed
Hemianopic visual field defects in children with intracranial shunts : report of two cases . - pubmed
CLINICAL PRESENTATION : Two cases are described in which homonymous hemianopsia resulted from unsuspected movement of the shunt catheter in growing children . - pubmed
In one male patient , the catheter tip impaled the optic tract , and in the other male patient the shunt became embedded in the midbrain tegmentum and shunt failure led to compression of the posterior cerebral artery . - pubmed
Some patients with chronic hepatitis C develop liver / kidney microsome type 1 antibodies . - pubmed
Serum from 24 patients with markers of hepatitis C infection and liver / kidney microsome type 1 antibodies were tested by immunoblotting with human liver microsomal proteins . - pubmed
Evaluation of glomerular lesion and abnormal urinary findings in OLETF rats resulting from a long - term diabetic state . - pubmed
Otsuka Long - Evans Tokushima Fatty ( OLETF ) rats have been established as an animal model in which non - insulin - dependent diabetes mellitus develops spontaneously . - pubmed
We examined the renal histopathology and the urinary findings serially in OLETF rats and compared these findings with findings in age - matched Long - Evans Tokushima Otsuka ( LETO ) rats as a control strain . - pubmed
Accompanying the development of hyperglycemia was an increase in the amount of albuminuria in OLETF rats from 18 weeks of age . - pubmed
Mesangial lesions progressed to mesangial sclerosis , and exudative lesions were found in OLETF rats from 36 weeks of age . - pubmed
The anionic charge of glomerular basement membrane ( GBM ) , measured by polyethyleneimine grain density , demonstrated that the lower grain density in OLETF rats when compared with that in LETO rats became more evident with an increase in the amount of albuminuria . - pubmed
Therefore , the defect in the charge - selective property found in OLETF rats might be one of the causes of albuminuria . - pubmed
The GBM became thickened in elderly OLETF rats as compared with that in age - matched LETO rats . - pubmed
Given these findings , we consider the OLETF strain of rats to be an interesting animal model for studying the relationship between diabetes and renal involvement , because the glomerular abnormalities and massive albuminuria found in OLETF rats were results of a long - term diabetic state . - pubmed
Retropharyngeal lymphadenopathy in patients with nasopharyngeal carcinoma : a computed tomography - based study . - pubmed
METHODS : From January 1989 to December 1991 , 364 patients with newly diagnosed nasopharyngeal carcinoma without distant metastasis had a baseline CT performed . - pubmed
No significant differences in relapse free survival rates , local control rates , lymph node control rates , or distant failure rates were observed between patients with or without retropharyngeal lymphadenopathy after adjusting for T and N classifications . - pubmed
In 134 patients with clinical N0 disease , retropharyngeal lymphadenopathy was found in 21 patients , whereas 113 had no evidence of retropharyngeal lymphadenopathy . - pubmed
It was shown on one generation of rats that CBL at dose of 1 g and 10 g per 1 kg of body mass had no an embryotoxic , gonadotoxic and teratogenic effects . - pubmed
Normotensive Wistar - Kyoto ( WKY ) rats responded to BilCAT like Sprague - Dawley rats , whereas spontaneously hypertensive rats ( SHR ) exhibited an exaggerated vasodepressor response to BilCAT ( -51 + /- 3 mmHg ) without increasing either UNaV or GFR . - pubmed
Healthy subjects ( n = 20 ) and hypertriacylglycerolemic patients ( n = 6 ) were given a placebo ( olive oil , OO ) or a fish - oil concentrate ( FOC ; 41 % eicosapentaenoic acid and 23 % docosahexaenoic acid ) in two , independent , randomized , blind trials . - pubmed
OBJECT : The purpose of this study was to determine whether intrinsic neuronal properties and synaptic responses differed between interictally active and inactive tissue removed in neocortical resections from patients undergoing surgical treatment for epilepsy . - pubmed
METHODS : Whole - cell patch recordings were performed in layer 2 or 3 and layer 5 pyramidal cells in neocortical slices obtained from tissue surgically removed from patients for the treatment of medically intractable seizures . - pubmed
Therapeutic and prognostic implications of peripheral blood lymphopenia in patients with Hodgkin ' s disease . - pubmed
Patients with Hodgkin ' s disease ( HD ) are known to have peripheral blood lymphopenia , but the prognostic significance of this observation and its implication on immune therapy remain controversial . - pubmed
We determined the peripheral blood lymphocyte ( PBL ) counts and their subsets of 238 newly diagnosed patients with HD referred to our institution , and the quantitative changes of B , T , and natural killer cells were correlated with the patients ' clinical variables . - pubmed
In this study , the decline in total PBL count or in its subsets in HD patients did not correlate with shorter disease free survival . - pubmed
Thus , strategies to improve lymphocyte functions in HD patients should continue to be explored therapeutically . - pubmed
In a patient with chronic neuroborreliosis , we show that this strategy leads to the identification of potentially relevant T - cell targets derived from both Borrelia burgdorferi and the host . - pubmed
Those strains from the outbreak of digestive disease belonged to serotype 050 : H11 and had a thermostable toxin . - pubmed
The first case of infectious neurologic syndrome with Plesionomas shigelloides etiology reported in Cuba was described ; the strain corresponded to serotype 050 : H11 . - pubmed
Six neurochemicals associated with a decrease in blood pressure were measured in humans ( n=18 ) and dogs ( n=18 ) before and after positive interaction . - pubmed
Altered activities of rat brain metabolic enzymes in electroconvulsive shock - induced seizures . - pubmed
The aim of this work was to investigate the influence of a single or repeated ECS - induced seizures on rat brain metabolism . - pubmed
OBJECTIVES : To study the prophylactic efficacy of lithium administered every second day to patients with bipolar disorder or recurrent unipolar depressive disorder . - pubmed
Participation in the study was conditional on the patient having been in prophylactic lithium treatment for the preceding 2 - year period and having been free of depressive or manic phases during the preceding 6 months . - pubmed
RESULTS : Forty - seven patients , 42 with a diagnosis of bipolar disorder and five with a diagnosis of recurrent unipolar depressive disorder , participated in the study . - pubmed
The remaining nine patients had recurrences , a number not differing from the 16 patients in the same group of 47 patients who , during the 2 - year period preceding the study , had recurrences . - pubmed
The mean 12 - h standard serum lithium concentration was lower in the patients who had recurrences than in those who stayed euthymic . - pubmed
[ A case of mucoid impaction of bronchi ( MIB ) due to Schizophyllum commune ] . - pubmed
Over the past 20 years at my institution , 71 patients with invasive necrotizing aspergillosis have been encountered ; 42 have shown central nervous system ( CNS ) involvement by autopsy ( 40 ) or surgical biopsy ( 2 ) . - pubmed
During the same period , single cases of cerebritis caused by morphologically similar fungi ( Pseudoallescheria boydii [ Scedosporium apiospermum ] , Scedosporium inflatum , Chaetomium sp ) were identified and were indistinguishable from CNS aspergillosis clinically and pathologically . - pubmed
Pupil signs of sympathetic autonomic neuropathy in patients with type 1 diabetes . - pubmed
We investigated pupil responsiveness to directly and indirectly acting sympathomimetics in type 1 diabetic patients with and without long - term complications , defined as cardiac autonomic neuropathy ( CAN ) , peripheral sensomotor neuropathy , retinopathy , and nephropathy , and in healthy subjects . - pubmed
RESEARCH DESIGN AND METHODS : A total of 47 randomly chosen type 1 diabetic patients and 20 healthy subjects were selected for this study . - pubmed
Patients were divided into groups determined by whether they had long - term diabetic complications . - pubmed
CONCLUSIONS : Our results clearly show that sympathetic denervation does exist in the pupil of diabetic patients and that it can be rapidly assessed using the cocaine test . - pubmed
The effects of Biopin ( ointment containing pine resin ) used in the treatment of burns , wounds , and pyoinflammatory processes on cell composition of the wound surface ( smears ) and granulation tissue were studied on rats . - pubmed
We report a case of DeBakey IIIb type dissecting aneurysm with adrenal myelo - lipoma in a 50 - year - old woman . - pubmed
The patient was referred to our hospital for severe back pain with severe hypertension . - pubmed
Adaptive changes related to medication treatment of ADHD : listening to parents of children in clinical trials of a novel nonstimulant medication . - pubmed
Increased intracranial blood flow volume in a preeclamptic woman with postpartum photophobia . - pubmed
We studied the changes in intracranial blood flow volume using a new color Doppler ultrasonographic assessment in a preeclamptic woman with photophobia . - pubmed
Specimens were derived from either the hippocampus or the temporal lobe cortex and from the tumor - free approach corridor tissue of patients with brain tumors . - pubmed
Does right hemisphere damaged patients ' impaired performance on a sentence insertion task indicate a syntactic or a lexical level deficit ? - pubmed
There is no cross - reactivity between mono - bactams or carbapenems with beta - lactams , and these drugs may be used safely in patients with anaphylactic reactions to beta - lactams . - pubmed
A case report is presented of an infant with jejunal atresia and hyperbilirubinemia with diagnosed pancreaticobiliary maljunction without choledochal dilatation . - pubmed
Infection rates of digenetic trematodes in the snails were 6.9 % in P. - pubmed
A rare case with Endamoeba histolytica in the ascites fluid and liver tissue ] . - pubmed
Axon dystrophy in clinically normal dogs . - pubmed
We aimed to evaluate the interdomal region in four fresh cadavers and 24 patients who underwent open rhinoplasty , since the nasal tip area is the most difficult part of the rhinoplasty . - pubmed
Preclinical data from chimpanzees and studies in hepatitis B virus / hepatitis C virus ( HCV ) coinfected transplant recipients suggest prophylactic HCV antibody therapy may have a role in the prevention of HCV recurrence . - pubmed
Preemptive antiviral therapy , started within the first 4 weeks posttransplantation and prior to the onset of clinical signs and symptoms , is effective in some patients ( 5 - 33 % ) and is not associated with an increased risk of acute rejection . - pubmed
Iron deficiency anemia as the only sign of infection with Helicobacter pylori : a report of 9 pediatric cases . - pubmed
Recently , an association between Helicobacter pylori ( HP ) and iron deficiency anemia ( IDA ) was proposed . - pubmed
The authors evaluated the results of a medial approach for the corrective osteotomy of 14 consecutive children ( mean age 8.4 years ) with cubitus varus . - pubmed
Clinical follow - up was performed on 151 patients ( 93 % ) , to identify the incidence of cardiac and neurological events and freedom from late death . - pubmed
[ Effect of cardiopulmonary bypass on selected neutrophil functions in children with cyanotic congenital heart disease ] . - pubmed
Children suffering from cyanotic congenital heart disease ( CCHD ) have been assumed to have a deficiency in their defence mechanisms . - pubmed
MATERIALS AND METHODS : 23 infants and children with congenital heart disease , scheduled for primary corrective surgical repair ; were enrolled . - pubmed
In severely burned rats , hyperemia , edema and other pathological injuries occur in the intestinal mucosa . - pubmed
In a randomised controlled trial , 92 patients with adhesive capsulitis received either high - grade mobilisation techniques or low - grade mobilisation techniques and were followed for one year . - pubmed
METHODS : In the present study , using leukapheresis products from 10 cancer patients , we validated an elutriation technology for large - scale clinical grade production of monocyte - derived DC . - pubmed
Prostate cancer remains the most common noncutaneous human malignancy , and the second most lethal tumor among men . - pubmed
A 62 - year - old woman , who had been diagnosed with sarcoidosis 3 years previously because of abnormalities on chest X - ray radiophotographs and lymph node pathology , was admitted to our hospital for the evaluation of proteinuria and microscopic hematuria . - pubmed
Cytomegalovirus is usually transmitted by direct human - to - human contact through vertical or horizontal routes . - pubmed
In the surgical literature , intestinal CMV - infected cells in infants have prevalently been associated with neonatal necrotizing enterocolitis , and only very few cases of primary CMV infection of the gastrointestinal tract of surgical interest in immunocompetent neonates have been reported . - pubmed
The authors present the cases of two children who developed relatively uncommon adverse effects to new anticonvulsant medications , including metabolic acidosis with topiramate and hyponatremia with oxcarbazepine . - pubmed
In one of our two patients , intraoperative acidosis related to topiramate was noted . - pubmed
In our second patient , hyponatremia and status epilepticus resulted from therapy with oxcarbazepine . - pubmed
By means of preimplantation genetic diagnosis ( PGD ) , we now can screen human embryos in vitro for aneuploidy before transferring the embryos to the uterus . - pubmed
Also , human placental cytotrophoblasts ( CTBs ) at the fetal - maternal interface acquire aneuploidies as they differentiate to an invasive phenotype . - pubmed
Synergistic muscle activation during maximum voluntary contractions in children with and without spastic cerebral palsy . - pubmed
We examined muscle recruitment patterns in children with cerebral palsy ( CP ) and comparison children without CP under conditions of maximum voluntary contractions . - pubmed
Three groups of children participated in the study : ( 1 ) 12 children with diplegic CP ( eight males , four females ; age range 4 - 10 y , mean age 7 y [ SD 2 y 4 mo ] ) ; ( 2 ) six children with hemiplegic CP ( four males , two females ; age range 5 - 10 y , mean age 7 y 4 mo [ SD 2 y ] ) ; and ( 3 ) 13 comparison children with normal motor function ( seven males , six females ; age range 4 - 11 y , mean age 7 y 2 mo , [ SD 2 y ] ) . - pubmed
The children with CP were classified according to the Gross Motor Function Classification System : eight were Level I , five were Level II , four were Level III , and one was Level IV . - pubmed
Children with CP more frequently activated a muscle other than the intended prime mover first , compared with the comparison children , especially when the prime mover was a distal muscle . - pubmed
In vitro chromosome aberration tests using human dental pulp cells to detect the carcinogenic potential of chemical agents . - pubmed
To examine if human dental pulp cells are useful for assessing the carcinogenic potential of chemical agents , we cultured human dental pulp cells from adults and studied the ability of chemical agents known to be carcinogenic to induce chromosome aberrations in these cells . - pubmed
Next , we examined if chromosome aberrations were induced by exposure of human dental pulp cells ( designated here as D824 cells ) at seven to nine passages to chemical agents with carcinogenic activity . - pubmed
Statistically significant increases in the frequencies of chromosome aberrations were induced in D824 cells treated with a direct - acting carcinogen , mitomycin C , for 3 h. Chromosome aberrations were also induced at statistically significant levels in D824 cells treated with an indirect - acting carcinogen , cyclophosphamide , for 2 h in the presence of exogenous metabolic activation with rat liver postmitochondrial supernatant . - pubmed
Although the reliability of chromosome aberration tests using human dental pulp cells remains to be validated by studying the ability of various other chemical agents with or without carcinogenic activity to induce chromosome aberrations , this chromosome aberration test system may be useful for carcinogenic risk assessment in the target cells . - pubmed
Classic treatments of osteogenesis imperfecta for children and adults include rehabilitation therapy and orthopedic surgery . - pubmed
However , further studies are needed to demonstrate an effect on fracture rate in children and adult patients . - pubmed
MATERIALS AND METHODS : Six patients with biochemical evidence of an insulinoma underwent pre - operative localisation studies and selective arterial calcium injection ( SACI ) . - pubmed
Those three patients , in whom magnetic resonance imaging and/or endosonography could localise the tumors pre - operatively , underwent laparoscopic surgery while the remaining three patients underwent open surgery . - pubmed
We report the case of a patient with unilateral AEC that was followed up over a 3 - year period and also discuss the role played by the right hemisphere in this disorder . - pubmed
A few days after the stroke the patient reported the inability to close his left eye on command , although he was still able to blink spontaneously and the blink and visual threat reflexes were preserved . - pubmed
PURPOSE : We report the feasibility of laparoscopic ipsilateral ureteroureterostomy for duplication anomalies of the urinary tract in infants and children , and the short - term results in 6 patients . - pubmed
PURPOSE : To evaluate the results of lacrimal probing in children at or older than 1 year of age with congenital nasolacrimal duct obstruction . - pubmed
MATERIALS AND METHODS : Fifty eyes of 38 children ( 24 males , 14 females ) with congenital epiphora who underwent nasolacrimal duct probing were evaluated in a prospective study . - pubmed
Residual epiphora was observed in 6 eyes of 4 patients ( 12 % ) . - pubmed
Age of the patient , gender , the frequency of epiphora before probing and the unilaterality or bilaterality of epiphora did not correlate with the success of probing ( p & gt ; 0.05 ) . - pubmed
Unsuccessful probing may result from the selection of nonmembranous obstructions rather than the increased age of the patients . - pubmed
The aim of the present study was to assess prospectively patients ' response to facet joint injection performed for lumbar back pain , and to check if it correlates with the response predicted by the Helbig and Lee scoring system . - pubmed
Fifty - seven patients who had facet joint injections for mechanical low back pain unresponsive to medical treatment , were followed - up . - pubmed
OBJECTIVE : The aim of this study was to extend a previous 2 - week assessment of a probiotic - prebiotic complex in patients with irritable bowel syndrome ( IBS ) . - pubmed
METHODS : In this open - label , partially controlled , 1 - year ( 14 [ 2 ] months ) extension study , data were collected from patients with IBS who continued treatment following a 2 - week study of the efficacy of the probiotic - prebiotic complex . - pubmed
Curcumin attenuates diabetic encephalopathy in rats : behavioral and biochemical evidences . - pubmed
on cognitive functions , oxidative stress and inflammation in diabetic rats . - pubmed
There was 107 % and 121 % rise in thiobarbituric acid reactive substance levels in cerebral cortex and hippocampus of diabetic rats , respectively . - pubmed
significantly attenuated cognitive deficit , cholinergic dysfunction , oxidative stress and inflammation in diabetic rats . - pubmed
The results emphasize the involvement of cholinergic dysfunction , oxidative stress and inflammation in the development of cognitive impairment in diabetic animals and point towards the potential of curcumin as an adjuvant therapy to conventional anti - hyperglycemic regimens for the prevention and treatment of diabetic encephalopathy . - pubmed
Twenty - nine patients with tuberculosis at the University Hospital in Vitoria , Brazil , participated . - pubmed
Participants included forty women , stratified into obese versus non - obese groups based upon their baseline body mass index , who had specimens corresponding to the three menopause stages . - pubmed
METHOD : Visuoperceptual , language , memory and frontal lobe functions were evaluated in 30 participants with severe motor impaired CP and a variety of speech difficulties . - pubmed
Laryngeal and hypopharyngeal obstruction in sleep disordered breathing patients , evaluated by sleep endoscopy . - pubmed
Despite the high response rates of small cell lung cancer ( SCLC ) to first - line cisplatin - based chemotherapies , most patients with SCLC will eventually experience disease progression . - pubmed
Newly developed multiple myeloma in a patient with primary T - cell lymphoma of bone . - pubmed
A 48 - yr - old man was diagnosed as T - cell PLB , stage IE , 18 months ago . - pubmed
The patient received the chemoradiotherapy and salvage chemotherapy for PLB . - pubmed
On bone marrow biopsy , the patient was diagnosed as having multiple myeloma newly developed with primary T - cell lymphoma of bone . - pubmed
In spite of chemotherapy , the patient died of renal failure . - pubmed
Patients in the WHI group experienced a significant reduction in pain score at 6 h ( P = 0.006 ) , 1 day ( P = 0.010 ) and 3 days ( P & lt ; 0.001 ) after operation , and in morphine usage on day 2 ( P = 0.040 ) . - pubmed
This prospective study aims at identifying the risk factors associated with infections , obstructions and surgical complications of these devices in pediatric patients . - pubmed
METHODS : From January 2006 to January 2008 , all children older than one year of age with a diagnosis of solid or blood cell malignancy were included in the study . - pubmed
Gentle cleansing and moisturizing for patients with atopic dermatitis and sensitive skin . - pubmed
Respiratory infections caused by nontypeable Haemophilus influenzae ( NTHi ) are a major medical problem . - pubmed
One resembled the European ( Eu ) type of potato tuber necrosis strain ( Eu - PVY ( NTN ) ) , possessing three widely recognized recombinant joints ( RJs 1 - 3 ) of the common strain ( PVY(O ) ) and the Eu - type tobacco veinal necrosis strain ( Eu - PVY(N ) ) . - pubmed
Crofelemer , a purified proanthocyanidin oligomer extracted from the bark latex of Croton lechleri , is in clinical trials for secretory diarrheas of various etiologies . - pubmed
Paradoxically , low body weight in middle aged and elderly humans is associated with increased mortality . - pubmed
Medulloblastoma in childhood : revisiting intrathecal therapy in infants and children . - pubmed
INTRODUCTION : Intrathecal chemotherapy is being explored in medulloblastoma in pre - school children as part of brain - sparing strategies and as an alternative to unacceptably neurotoxic cranio - spinal radiotherapy . - pubmed
Retinol - induced intestinal tumorigenesis in Min/+ mice and importance of vitamin D status . - pubmed
The effects of life - long dietary exposure , starting in utero , to high retinol , low vitamin D , or high retinol in combination with low vitamin D on intestinal tumorigenesis in Min/+ mice were investigated . - pubmed
In males , high retinol alone significantly increased the number ( 2.6 - fold ) and size ( 1.3 - fold ) of small intestinal tumours ; in females no significant increase in tumour number or size was seen . - pubmed
In females , however , the high retinol / low vitamin D - induced increase in tumour number ( 3.1 - fold ) and tumour size ( 1.5 - fold ) exceeded that of high retinol alone . - pubmed
METHOD : Patients who developed osteonecrosis as a complication of ALL therapy between 1994 and 2007 were treated at a single paediatric institution . - pubmed
All patients demonstrated reduction in the radiological burden of osteonecrosis with time . - pubmed
CONCLUSION : Bisphosphonate use , in particular pamidronate , improved pain scores , analgesic requirement and musculoskeletal function in patients with osteonecrosis occurring as a complication of childhood ALL therapy . - pubmed
In this study we highlight the high prevalence and relatively low control rate of misdiagnosed IP ( pathology undetermined pre - operatively ) and hope to remind clinicians that early recognition of the tumour is most beneficial to patients . - pubmed
CASE PRESENTATION : A 46 - year - old woman was hospitalized with a preoperative diagnosis of gallbladder carcinoma , The patient was referred for surgical opinion and laparotomy was subsequently performed . - pubmed
Transurethral endoscopic treatment of patients with upper tract urothelial carcinomas using neodymium - YAG and/or holmium - YAG laser ablation . - pubmed
OBJECTIVE : To report our experience of treating patients with original and recurrent upper tract urothelial carcinomas ( UC ) using endoscopic lasers , with holmium - YAG and/or neodymium - YAG laser ablation , and for whom tumour stage and grade were obtained by endoscopic biopsy . - pubmed
PATIENTS AND METHODS : From March 2003 to March 2007 , 15 patients with upper tract UC were treated with endoscopic laser ablation as the primary management . - pubmed
RESULTS : Of the 15 patients , five had an upper tract recurrence during the follow - up . - pubmed
Three patients had residual tumours ; they were treated with repeated endoscopic laser treatments and had no recurrence over a median ( range ) of 24 ( 13 - 26 ) months . - pubmed
PATIENT(S ): One hundred nineteen women with infertility and 99 healthy female controls without infertility between the ages of 18 and 45 years were included in this study . - pubmed
To see whether this longevity is associated with orthopaedic disability , especially physeal growth defects , we examined 105 patients aged between 5 - 25 years for evidence of clinically detectable premature epiphyseal fusions ( PEF ) . - pubmed
We aimed to examine the impact of dysglycemia on outcomes in 173 recipients of HCT treated with glucocorticoids for aGVHD . - pubmed
These data suggest an independent adverse effect of dysglycemia in patients treated with glucocorticoids for aGVHD , and argue for stringent glycemic control in this setting . - pubmed
We have recently shown that the cholesterol oxidation metabolite 27 - hydroxycholesterol ( 27 - OHC ) causes AD - like pathology in human neuroblastoma SH - SY5Y cells and in organotypic hippocampal slices . - pubmed
The rapidly - changing pattern of gonococcal antimicrobial susceptibility warrants the need for an antimicrobial susceptibility - monitoring programme , and periodical analysis and dissemination of susceptibility data are essential to guide clinicians and for successful STI / HIV intervention programmes . - pubmed
We compared the frequency of myelosuppressive chemotherapy treatment , erythropoiesis - stimulating agent administrations , and red blood cell transfusions before and after the National Coverage Decision in oncology patients with chemotherapy - induced anemia . - pubmed
RESULTS : A 32 - year - old man presented with a typical image of neuroretinitis , retinal hemorrhages and sheathing of the retinal veins in the nasal retina . - pubmed
Between 2005 and 2010 , 362 patients underwent elective lung resection for malignant or benign lung tumors . - pubmed
Of the seven patients , six had primary lung cancer ( PLC ) , and one had metastatic cancer of the lung . - pubmed
PQ was administered to Balb / c mice as intraperitoneal doses of 0.01 , 0.1 , or 1.0 mg PQ / kg body weight ( BW ) for a total of 28 days . - pubmed
During a high speed road traffic accident , a 26 - year - old man suffered multiple fractures of his thoracic vertebrae and bilateral pneumothoraces . - pubmed
A 62 - year - old female patient with a chief complaint of back pain and continuous fever was referred to our hospital . - pubmed
Combination chemotherapy consisting of gemcitabine and doxorubicin is a treatment option for patients with spindle cell renal cell carcinoma . - pubmed
BACKGROUND : Indonesia is one of the countries most severely affected by H5N1 highly pathogenic avian influenza ( HPAI ) virus in terms of poultry and human health . - pubmed
In this study , H5N1 virus infection occurring in 96 smallholder duck farms in central Java , Indonesia from 2007 - 2008 was investigated and the molecular and antigenic characteristics of H5N1 viruses isolated from these farms were analysed . - pubmed
The high proportion of live duck cases compared to chickens over the study period suggests that ducks are more likely to survive infection and they may better suit the role of long - term maintenance host for H5N1 . - pubmed
Clinical characteristics in 53 patients with cat scratch optic neuropathy . - pubmed
OBJECTIVE : To describe the clinical manifestations and to identify risk factors associated with visual outcome in a large cohort of patients with cat scratch optic neuropathy ( CSON ) . - pubmed
Only 5 patients had significant visual complications ( branch retinal artery occlusion , macular hole , and corneal decompensation ) . - pubmed
CONCLUSIONS : Patients with CSON have a good overall visual prognosis . - pubmed
Relative to time of diagnosis , the preclinical AD persons deviated from the normal aging curve earlier ( up to 9 years ) compared to the preclinical VaD persons ( up to 6 years ) . - pubmed
Developmentally altered inhibition in Ts65Dn , a mouse model of Down syndrome . - pubmed
Different from other types of strabismus , children with intermittent exotropia can maintain normal eye alignment and binocular vision in a long period of time . - pubmed
Prior research suggests that HCQ may reduce the risk of diabetes mellitus in patients with RA . - pubmed
A diet low in animal fat and rich in N - hexacosanol and fisetin is effective in reducing symptoms of Parkinson ' s disease . - pubmed
METHODS : Forty - five patients with AOSD ( active = 22 , inactive = 23 ) and 32 healthy controls were included . - pubmed
Twenty - four patients with AOSD and 18 controls were examined for cytotoxic activity of NK cells by co - incubating NK cells with NK - sensitive K562 cells . - pubmed
RESULTS : The proportions of NK cells were significantly lower in patients with active AOSD than in patients with inactive disease and controls . - pubmed
NK cell cytotoxic function was significantly lower in patients with AOSD than in controls . - pubmed
NK cell proportions and cytotoxic functions were reexamined in 11 and 6 patients , respectively , after treatment . - pubmed
Low NK cell proportion and cytotoxic dysfunction were improved with clinical improvements of the patients . - pubmed
BACKGROUND : Arsenic Trioxide ( ATO ) is effective in about 20 % of patients with myelodysplasia ( MDS ) ; its mechanisms of action have already been evaluated in vitro , but the in vivo activity is still not fully understood . - pubmed
For this analysis , we selected 12 patients affected by MDS who received ATO in combination with Ascorbic Acid in the context of the Italian clinical trial NCT00803530 , EudracT Number 2005 - 001321 - 28 . - pubmed
Two patients achieved a major response : in the patient with refractory anemia the treatment down - regulated 69 % of the pro - apoptotic genes , whereas 91 % of the pro - apoptotic genes were up - regulated in the patient affected by refractory anemia with excess of blasts-1 . - pubmed
We assessed the perspectives of community - dwelling individuals with chronic stroke on their hand function limitations and recovery to explore the feasibility of developing a theoretical framework for understanding the process of continued post - stroke recovery . - pubmed
METHODS : Eight subjects with chronic post - stroke hemiparesis were interviewed and videotaped while they performed a battery of 20 upper limb tasks . - pubmed
CONCLUSIONS : These themes suggest a therapeutic framework for continued upper limb rehabilitation in patients ' own environment to maximize functional recovery in individuals long after their stroke , and generate hypotheses which may lead to the development of new therapeutic protocols . - pubmed
Risk for nephropathy is highest in dogs homozygous for the mutations ( OR = 9.06 ; 95 % CI = 4.24 - 19.35 ) . - pubmed
This is the first molecular characterization of an inherited podocytopathy in dogs and may serve as a model for continued studies of complex genetic and environmental interactions in glomerular disease . - pubmed
Enzootic pneumonia , resulting from infection with Mycoplasma hyopneumoniae , is of considerable economic importance to the pig industry and normally is controlled through active vaccination of piglets . - pubmed
We have demonstrated that administration of an inactivated Mycoplasma hyopneumoniae vaccine to piglets less than 1 week old is efficacious under field conditions and reduces the level of lung lesions observed in comparison to that in control pigs . - pubmed
The number of lung lesions was recorded 4 weeks after challenge , and bronchial swab and lung tissue specimens were analyzed for quantification of Mycoplasma hyopneumoniae DNA . - pubmed
PURPOSE : The aim was to compare preventive effect of total parenteral nutrition ( TPN ) and oral nutrition ( preOp ) on the perioperative insulin resistance prevention in surgical gastrointestinal cancer patients . - pubmed
MATERIAL / METHODS : The study was conducted in a group of 75 elective gastric and large intestine cancer patients . - pubmed
However , a majority of strains were isolated from rocky shores and , in particular , red seaweed surfaces and mollusks . - pubmed
The 14 patients in the active microcurrent group [ mean , 10.8 ( 2.9 ) days ; range , 7 - 15 days ] experienced no difference in time to wound healing as compared to the remaining patients in the sham microcurrent group [ mean , 11.1 ( 2.0 ) days ; range , 8 - 14 days ; P = 0.75 ] . - pubmed
CONCLUSIONS : In a sample size of 25 burn patients , the addition of direct microcurrent to silver - nylon dressings did not decrease time to wound closure of skin donor sites , and it did not show a difference in reported pain levels . - pubmed
Cardiovascular responses during a submaximal exercise test in patients with Parkinson ' s disease . - pubmed
BACKGROUND : Patients with Parkinson ' s disease ( PD ) are physically less active than controls , and autonomic dysfunction may contribute to this sedentary lifestyle . - pubmed
OBJECTIVE : To assess the cardiovascular responses to a submaximal exercise test in PD patients and controls , 546 sedentary PD patients and 29 sedentary healthy controls performed the Astrand - Rhyming submaximal cycle exercise test . - pubmed
Variables that may affect submaximal activity in PD patients , including disease severity , fatigue , and level of physical activity in daily life , were recorded . - pubmed
RESULTS : Fewer PD patients ( 46 % ) completed the submaximal exercise test successfully than the controls ( 86 % ) . - pubmed
PD patients with a successful submaximal exercise test had lower estimated VO2max values than controls . - pubmed
Pre - clinical studies and recently reported human trials suggest that pre - erythrocytic stage vaccines can provide protection against infection . - pubmed
PATIENTS AND METHODS : 80 women ( mean age 73 + - 5 years ) with early breast cancer were retrospectively evaluated . - pubmed
30 - 45 days after the percutaneous ablation , all patients underwent surgical resection of the tumor . - pubmed
In 75 patients ( 93.8 % ) we observed complete necrosis ; in 5 cases there was residual disease in the postprocedural MRI and postoperative histological examination . - pubmed
Here we uncover roles for mitochondrial reactive oxygen species ( mtROS ) during Drosophila dorsal closure , a model for wound healing . - pubmed
RESULTS : Children with cCMV ( n=34 ; 12 males , 22 females ; mean [ SD ] gestational age , 36.4 wk [ 4.4 ] , range 24 - 41 wk ) accounted for 1.5 % of CP cases ; 2.9 per 100,000 live births , ( 95 % confidence intervals 1.9 - 3.9 ) . - pubmed
The majority of the patients are treated with the sphincter - sparing surgical procedure low anterior resection , and 50 % to 90 % of these patients experience bowel dysfunction , known as the low anterior resection syndrome . - pubmed
PATIENTS : All patients had undergone low anterior resection for rectal cancer , had no stoma , had no dissemination or recurrence at the time of the study , and were at least 16 months past surgery . - pubmed
In comparison with patients without low anterior resection syndrome , patients with major low anterior resection syndrome fared substantially worse in all selected subscales ( difference & gt;= 10 points , p & lt ; 0.01 ) , with the exception of constipation . - pubmed
The majority of studies contain a heterogeneous cohort of subjects , often combining patients with and without spondylolisthesis who received various surgical interventions , limiting fusions to those patients with instability . - pubmed
It is difficult if not impossible , therefore , to formulate valid conclusions regarding the utility of fusion for patients with uncomplicated stenosis . - pubmed
The patient was a 47 - year - old man with deep - vein thrombosis . - pubmed
The prevalence of EEG , PHES and CFFo / CFFm abnormalities was significantly higher in patients with grade I overt HE . - pubmed
The prevalence of EEG abnormalities was significantly higher in patients with a history of HE . - pubmed
This paper reports distinctive temporal - volatile profiles from three abiotic treatments , room temperature ( control ) , -15 C ( cold ) , and -15 C to room temperature ( shock ) , of cactus tissue plugs . - pubmed
Plasma total 25 ( OH ) D , 25 ( OH ) D2 , and 25 ( OH ) D3 levels were measured by liquid chromatography - tandem mass spectrometry in PD patients ( n = 478 ) and controls ( n = 431 ) . - pubmed
The current study , however , can not exclude the possibility that gastrointestinal dysfunction , a non - motor PD symptom , contributes to the lower vitamin D2 levels in PD patients . - pubmed
The study also revealed a high prevalence of infection in P. - pubmed
We report the outcomes of a series of patients with pelvic recurrences from colorectal cancer reirradiated with SBRT . - pubmed
Early diagnosis can result in prompt management of the patient since wrist pain in older individuals due to aging may go unnoticed or be due to other diagnoses with the production of greater damage and eventually a worse prognosis . - pubmed
Given that older and stronger memories are generally more resistant to change , we tested whether disrupting reconsolidation would also diminish fear in individuals who had developed a persistent spider fear outside the laboratory . - pubmed
Depression in patients with alcohol use disorders : Systematic review and meta - analysis of outcomes for independent and substance - induced disorders . - pubmed
BACKGROUND : In patients with an alcohol use disorder , depression is commonly categorised as independent ( ID ) or substance - induced ( SID ) . - pubmed
The effect of antidepressant therapy on depression in patients with alcohol use disorders is modest , with stronger evidence in ID . - pubmed
Postmenopausal women experienced pain during SCSH more often than premenopausal women did : 71 % ( 17/24 ) compared with 32 % ( 24/75 ) experienced pain ; p & lt ; 0.002 ; the median tolerance on the 100 - mm visual analog scale was 43 . - pubmed
MATERIALS AND METHODS : A retrospective chart review study was conducted at Department of Clinical Chemistry , King Abdulaziz Medical City ( KAMC ) in Riyadh , Saudi Arabia , during the period from August 2014 to December 2014 , including 100 male and female patients diagnosed with diabetes mellitus ( DM ) type 2 and excluding patients with DM type 1 . - pubmed
In the third simulated trial , risk of MACE was significantly greater in patients switching from rosuvastatin to atorvastatin than in those remaining on rosuvastatin ( RR at 5 years : 1.109 ; P<0.001 ) . - pubmed
Proteomic profiling of epileptogenesis in a rat model : Focus on inflammation . - pubmed
The questionnaire included questions about pain and sensory abnormalities located to the abdominal skin , and physical and psychological function ; patient satisfaction with surgery was rated on a 4 - point scale . - pubmed
MATERIALS AND METHODS : Chronic kidney disease was created in C57BL / 6 mice ; 28 days later , an AVF was created by connecting the right carotid artery to the ipsilateral jugular vein . - pubmed
METHODS : In a sample of 70 twins discordant for schizophrenia and 130 healthy control twins , structural equation modeling was applied to quantify unique contributions of genetic and environmental factors on human brain structure ( cortical thickness , cortical surface and global white matter fractional anisotropy [ FA ] ) , intellectual ability and schizophrenia liability . - pubmed
METHODS : Here , 107 patients with biopsy - proven locally advanced NPC between March 2004 and January 2011 were enrolled in the retrospective study . - pubmed
The activity of enzymes of glycolysis has been studied in erythrocytes from type - II diabetic patients in comparison with control . - pubmed
cerulea and Quercus agrifolia Nee against a DeltatolC mutant strain of Escherichia coli . - pubmed
Poster 321 Trazodone Associated Clitoral Priapism in a Transgender Man following Traumatic Brain Injury : A Case Report . - pubmed
Actinomycosis is a chronic suppurative granulomatous infection of subcutaneous tissues caused by bacterium Actinomyces israelii . - pubmed
Infection is first established locally by breach of mucosal barrier during various procedures , aspiration , trauma , or human bite . - pubmed
In this study , we enhance the radiosensitivity of HCT116 human colorectal cells with tiopronin - coated GNPs ( Tio - GNPs ) combined with a low - energy X - ray ( 26 keV effective energy ) source , similar to the Papillon 50 clinical irradiator used for topical irradiation of rectal tumors . - pubmed
In nude mice bearing the HCT116 tumor , intra - tumoral ( IT ) injection of Tio - GNPs allowed a 94 times higher quantity of Tio - GNPs to accumulate than was possible by intravenous injection and facilitated a significant tumor response . - pubmed
It includes the topics 1 ) gambling disorder from the neuroimaging and electroencephalography ( EEG ) perspective , 2 ) cognitive , executive functioning , and neuropsychological aspects of gambling disorder , and 3 ) rodent models of gambling disorder . - pubmed
INTRODUCTION : The aim is to analyze the functional outcomes of patients of giant cell tumor ( GCT ) of distal radius treated with ulnar translocation and wrist arthrodesis . - pubmed
METHODS : Study included 25 patients of aggressive GCT of distal radius , resected and reconstructed using ulnar translocation and wrist arthrodesis . - pubmed
The aim of this study was to evaluate the authors ' experience of sialendoscopy of the salivary glands in patients with SS . - pubmed
MATERIALS AND METHODS : In this retrospective case series study , the surgical data of patients with SS who had undergone sialendoscopy at the VU University Medical Center ( Amsterdam , The Netherlands ) from November 2014 through April 2015 were used . - pubmed
RESULTS : Surgical data of sialoendoscopic procedures in 26 patients with SS ( 24 women and 2 men ; mean age , 57 yr ; range , 27 to 72 yr ) were analyzed . - pubmed
Three patients developed a postoperative infection . - pubmed
CONCLUSION : The overall rate of complications was limited and the sialoendoscopic complications in patients with SS could be regarded as minor . - pubmed
Design and rationale for the WARFA trial : a randomized controlled cross - over trial testing the therapeutic equivalence of branded and generic warfarin in atrial fibrillation patients in Brazil . - pubmed
METHODS : Prospective cohort of consecutive patients with ASBO . - pubmed
MAIN OUTCOME : Intestinal necrosis ( IN ) in 10 patients ( 21.3 % ) . - pubmed
CONCLUSIONS : PCT levels are closely related to the presence of intestinal ischemia and necrosis in children with ASBO . - pubmed
The Combined Intervention with Germinated Vigna radiata and Aerobic Interval Training Protocol Is an Effective Strategy for the Treatment of Non - Alcoholic Fatty Liver Disease ( NAFLD ) and Other Alterations Related to the Metabolic Syndrome in Zucker Rats . - pubmed
In the present experiment , the combined treatment with mung bean ( Vigna radiata ) , a widely used legume with promising nutritional and health benefits that was included in the experimental diet as raw or 4 day - germinated seed flour , and aerobic interval training protocol ( 65 - 85 % VO2 max ) has been tested in lean and obese Zucker rats following a 2 x 2 x 2 ( 2 phenotypes , 2 dietary interventions , 2 lifestyles ) factorial ANOVA ( Analysis of Variance ) statistical analysis . - pubmed
radiata at improving the aerobic capacity and physical performance , hepatic histology and functionality , and plasma lipid parameters as well as reverting the insulin resistance characteristic of the obese Zucker rat model . - pubmed
In conclusion , the joint intervention with legume sprouts and aerobic interval training protocol is an efficient treatment to improve the alterations of glucose and lipid metabolism as well as hepatic histology and functionality related to the development of NAFLD and the MetS. - pubmed
Numerous studies have demonstrated the suitability of zebrafish ( Danio rerio ) embryos as a model to in vivo studies of Pseudomonas aeruginosa infection . - pubmed
In most zebrafish - pathogen studies , infection is achieved by microinjection of bacteria into the larvae . - pubmed
METHODS : We performed intravascular ultrasound ( IVUS ) with virtual histology in 98 patients prior to elective bare - metal stent ( BMS ) implantation in de novo coronary artery lesions . - pubmed
Subgroup analysis after exclusion of acute coronary syndrome ( ACS ) patients yielded similar results . - pubmed
SUBJECTS AND METHODS : One hundred and fifty patients with epilepsy were recruited between May 2016 and August 2016 . - pubmed
For assessing depression , Tamil validated version of Patient Health Questionnaire-12 was used . - pubmed
Depressive symptoms were present in 95 patients ( 63.3 % ) . - pubmed
First time non - cardiogenic ischemic stroke patients were enrolled and screened within 30 days . - pubmed
Participants were randomized to receive either triflusal or clopidogrel for secondary stroke prevention . - pubmed
According to Paprosky classification , 2 patients had type IIB defect , 4 had type IIC , and 12 had type IIIA , while 8 suffered from type IIIB defect . - pubmed
Early brain injury ( EBI ) is the primary cause of poor outcome in subarachnoid hemorrhage ( SAH ) patients . - pubmed
Adult male Sprague - Dawley rats were subjected to an endovascular perforation process to produce an SAH model . - pubmed
Edoxaban for the Treatment of Venous Thromboembolism in Patients with Cancer . - pubmed
Congenital anomalies of the kidney and urinary tract ( CAKUT ) are among the most common developmental defects in humans . - pubmed
Methods : We compared the prognostic value of traditional demographic and cytogenetic risk factors , genomic data in the form of somatic aberrations of 25 AML - relevant genes , and whole - transcriptome expression profiling ( RNA sequencing ) in 267 intensively treated AML patients ( Clinseq - AML ) . - pubmed
METHODS : A total of 28 patients ( n = 14 , 46,XX ; n = 14 , 46,XY ) with classical 11BOHD from 25 unrelated families were included in this study . - pubmed
Two male patients had testicular microlithiasis and 5 ( 35.7 % ) patients had testicular adrenal rest tumor during follow up . - pubmed
Four patients ( 28.6 % ) had gynecomastia . - pubmed
METHODS : From forty 4 - 5 months old SD rats , 30 were randomly selected for the establishment of the model of testicular UU infection by inoculating the bladder with UU suspension and the other 10 injected with normal saline as controls ( group A ) . - pubmed
At 7 days after inoculation , the rat models of testicular UU infection were treated orally with normal saline ( group B ) , ZDD at 1 g per kg of the body weight per day ( group C ) , and azithromycin at 0.105 g per kg of the body weight per day ( group D ) , respectively , once daily for 21 days . - pubmed
Objective : To determine if patients with OSA have thinner skulls than patients without OSA . - pubmed
Patients with moderate to severe OSA ( apnea - hypopnea index [ AHI]>=25 / h ) and without OSA ( AHI<5 / h ) were matched for age and body mass index ( BMI , calculated as weight in kilograms divided by height in meters squared ) . - pubmed
Patients with OSA had thinner mean ( SD ) calvaria ( 2.73 [ 0.67 ] vs 2.47 [ 0.52 ] mm ; difference , -0.26 mm ; 95 % CI , -0.49 to -0.04 ; Cohen d , 0.44 ) and thinner skull bases ( 5.03 [ 1.40 ] vs 4.32 [ 1.28 ] mm ; difference , -0.71 ; 95 % CI , -1.23 to -0.19 ; Cohen d , 0.53 ) . - pubmed
The tegmen mastoideum was dehiscent in nearly twice as many patients with OSA as those without ( 37 % vs 20 % ; difference , 17 % ; 95 % CI , 0.4 - 32 ) . - pubmed
METHODS : Three radio - resistant human rectal cancer cell lines ( SNU-61R80Gy , SNU-283R80Gy , and SNU-503R80Gy ) were established from human rectal cancer cell lines ( SNU-61 , SNU-283 , and SNU-503 ) using total 80 Gy of fractionated irradiation . - pubmed
Microarray analysis was performed to identify differently expressed genes in newly established radio - resistant human rectal cancer cells compared to parental rectal cancer cells . - pubmed
To evaluate whether the alpha , beta - unsaturated carbonyl can be used for intracerebral hemorrhage ( ICH ) therapy , we investigated the effect of shogaol on an in vivo mouse ICH model . - pubmed
Transpulmonary pressure , that is the difference between airway pressure ( Paw ) and pleural pressure , is considered one of the most important parameters to know in order to set a safe mechanical ventilation in acute respiratory distress syndrome ( ARDS ) patients but also in critically ill obese patients , in abdominal pathologies or in pathologies affecting the chest wall itself . - pubmed
Esophageal pressure ( Pes ) is considered the best surrogate of pleural pressure in critically ill patients , but concerns about its reliability exist . - pubmed
Protein - rich extract of Musca domestica larvae alleviated metabolic disorder in STZ - induced type 2 diabetic rat model via hepatoprotective and pancreatic beta - cell protective activities . - pubmed
The study was designed to explore the beneficial effect of Musca domestica larvae extract ( MDLE ) on a metabolic disorder using a diabetic rat model . - pubmed
Streptozotocin - induced diabetic rats were treated with or without MDLE . - pubmed
Tanoak ( Lithocarpus densiflorus ) is a principal host of Phytophthora ramorum , cause of sudden oak death ( SOD ) , in the western United States ( 1 ) . - pubmed
A lung - tumor patient was simulated with differently shaped tumor - mimicking inlays in a thorax - phantom . - pubmed
[ Possibilities and advantages of minimally invasive dorsal decompressive - stabilizing interventions in the treatment of degenerative spondylolisthesis of the elderly patients . ] - pubmed
The purpose of the study was a comparative analysis of the clinical and radiographic efficacy of minimally invasive rigid stabilization techniques and the traditional open interbody fusion with transpedicular fixation in the treatment of degenerative spondylolisthesis in elderly patients . - pubmed
Low traumatic surgery in the main study group makes it possible to use a technique for treating degenerative spondylolisthesis in elderly patients . - pubmed
METHODS : From January 2016 through March 2018 , consecutive children with CLD without a history of variceal bleeding were prospectively included . - pubmed
Esophagogastroduodenoscopy was done in all the children to detect and to grade esophageal varices . - pubmed
RESULTS : Of 288 patients with RA , 204 ( 70.8 % ) and 84 ( 29.2 % ) continued standard dose treatment and underwent down - titration treatment , respectively . - pubmed
METHODS : For this feasibility study , we enrolled 27 adult patients presenting to the day hospital with acute pain . - pubmed
As expected , we found that pain scores and heart rate decreased for most patients during the course of their stay . - pubmed
Safety and Efficacy Evaluation of Traditional Chinese Medicine ( Qingre - Lishi - Yishen Formula ) Based on Treatment of Regular Glucocorticoid Combined with Cyclophosphamide Pulse in Children Suffered from Moderately Severe Henoch - Schonlein Purpura Nephritis with Nephrotic Proteinuria . - pubmed
Objective : At present , the most appropriate management of Henoch - Schonlein purpura nephritis ( HSPN ) with nephrotic - range proteinuria still remains controversial ; thus , the purpose of this study is to evaluate safety and efficacy of traditional Chinese medicine ( TCM ) , Qingre - Lishi - Yishen Formula ( QLYF ) , integrated with regular oral glucocorticoid and cyclophosphamide intravenous pulse therapeutic regimen in children suffered from moderately severe HSPN with nephrotic proteinuria . - pubmed
Methods : From 1 January 2012 , to 1 January 2016 , totally 150 hospitalized children suffered from HSPN with nephrotic proteinuria were included . - pubmed
Results : Total adverse event rate was lower in the QLYF group ( chi 2 = 5.357 , p = 0.022 ) ; rates of respiratory infection , urinary infection , poor appetite , hepatotoxity , cardiotoxicity , and neutropenia were all decreased in patients who received QLYF ( p = 0.022 ) ; rates of respiratory infection , urinary infection , poor appetite , hepatotoxity , cardiotoxicity , and neutropenia were all decreased in patients who received QLYF ( p = 0.022 ) ; rates of respiratory infection , urinary infection , poor appetite , hepatotoxity , cardiotoxicity , and neutropenia were all decreased in patients who received QLYF ( p = 0.022 ) ; rates of respiratory infection , urinary infection , poor appetite , hepatotoxity , cardiotoxicity , and neutropenia were all decreased in patients who received QLYF ( p = 0.022 ) ; rates of respiratory infection , urinary infection , poor appetite , hepatotoxity , cardiotoxicity , and neutropenia were all decreased in patients who received QLYF ( p = 0.022 ) ; rates of respiratory infection , urinary infection , poor appetite , hepatotoxity , cardiotoxicity , and neutropenia were all decreased in patients who received QLYF ( . - pubmed
Conclusion : Compared with merely using regular oral glucocorticoid plus cyclophosphamide pulse therapeutic regimen , the therapeutic regimen that integrates QLYF with the abovementioned western medicine might be a safe means to decrease the occurrence rate of adverse events and improve short - term and long - term clinical effects in children who suffered from moderately severe HSPN with nephrotic proteinuria . - pubmed
Favipiravir cures all mice in a lethal influenza infection model , while oseltamivir fails to cure the animals . - pubmed
In addition to influenza , favipiravir has a broad spectrum of anti - RNA virus activities in vitro and efficacies in animal models with lethal RNA viruses and has been used for treatment of human infection with life - threatening Ebola virus , Lassa virus , rabies , and severe fever with thrombocytopenia syndrome . - pubmed
The primary endpoint was the development of sepsis between 2011 and 2015 , and the secondary endpoint was 30 - day mortality among diabetes patients diagnosed with sepsis . - pubmed
CONCLUSIONS : Prior metformin therapy was not significantly associated with the risk of sepsis and 30 - day mortality after diagnosis of sepsis among diabetes patients . - pubmed
AEN can arise in critically ill patients with multiple comorbidities and is an uncommon complication of diabetic ketoacidosis ( DKA ) . - pubmed
We present a case of a young female with poorly controlled , insulin - dependent diabetes mellitus type 2 who developed odynophagia , small volume coffee - ground emesis , and inability to tolerate oral intake after resolution of DKA . - pubmed
Thus , AEN should be considered in the differential diagnosis for critically ill patients who present with vague symptoms such as odynophagia and gastrointestinal bleeding . - pubmed
In fingolimod - treated patients only , female sex and a higher Expanded Disability Status Scale score were predictors of lymphopenia at 12 months ( p = 0.006 , odds ratio = 7.58 and p = 0.03 , odds ratio = 1.56 ) . - pubmed
CONCLUSIONS : Our findings suggest that peripheral blood lymphocyte changes are not associated with short - term treatment response and with the rate of infections during fingolimod and dimethyl - fumarate treatment in real - world patients . - pubmed
METHODS : This study included 110 BPH patients treated in our hospital from August 2017 to April 2018 , who were randomly assigned to receive HoLEP ( n = 55 ) or HoLEP + JSSD ( n = 55 ) . - pubmed
CONCLUSIONS : HoLEP + JSSD can significantly alleviate the lower urinary tract symptoms as well as improve the QOL and bladder and urinary tract functions of BPH patients . - pubmed
Patients with acute myocardial infarction experienced a higher number of hypoglycemic events compared with unstable angina diagnosed patients . - pubmed
In our previous study , Hydrostatin - SN1 , a bioactive peptide extracted from the Hydrophis cyanocinctus venom gland T7 phage display library , demonstrated anti - inflammatory activity in a dextran sulfate sodium - induced murine colitis model . - pubmed
In LPS - induced acute shock model , a significant higher survival rate of Hydrostatin - SN1 - treated mice was observed . - pubmed
CASE PRESENTATION : We report the case of a 65 - year - old male with a PPMM who has prolonged survival of more than 104 weeks after combined microsurgical and endoscopic total resection . - pubmed
BACKGROUND : Hypokalemia and hypomagnesemia caused due to renal losses with chloride - resistant metabolic alkalosis in normotensive patients should remind clinicians of the rare inherited tubulopathy , Gitelman syndrome . - pubmed
CONCLUSION : This lifelong disease could cause life - threatening conditions due to the cardiac complications of hypokalemia in some of the affected patients . - pubmed
Therefore , it is necessary to be aware of the appropriate diagnosis and treatment for patients admitted to the clinic with hypokalemia , hypomagnesemia , hypocalciuria , and hyperreninemia . - pubmed
A weight of evidence assessment of the genotoxic potential of 4 - methylimidazole as a possible mode of action for the formation of lung tumors in exposed mice . - pubmed
Two - year rodent bioassays via oral exposure conducted by the National Toxicology Program reported evidence of carcinogenicity only in B6C3F1 mice ( increased alveolar / bronchial neoplasms ) . - pubmed
In 2011 , the International Agency for Research on Cancer classified 4 - MeI as Group 2B , " possibly carcinogenic to humans " . - pubmed
An expert panel was commissioned to assess the genotoxic potential of 4 - MeI and the plausibility of a genotoxic mode of action in the formation of lung tumors in mice when exposed to high doses of 4 - MeI. - pubmed
Based on the reviewed studies ' weighted contribution , the panel unanimously concluded that the WOE supports no clear evidence of in vivo genotoxicity of 4 - MeI and no association for a genotoxic mode of action in the formation of mouse lung tumors . - pubmed
AF was associated with early discontinuation of trastuzumab in patients with breast cancer . - pubmed
Tumor sizes of patients in the TACE - apatinib group were more frequently classified as small ( < 5 cm ) compared to those in the TACE alone group ( P = 0.021 ; mean : 8.6 cm vs. 10.2 cm ) . - pubmed
Conclusions : TACE combined with apatinib may result in superior OS compared to TACE therapy alone for HCC patients with macrovascular invasion . - pubmed
METHODS : Infants with congenital heart disease were randomly divided into the breast milk oral stimulation group ( n = 23 ) , physiological saline oral stimulation group ( n = 23 ) and control group ( n = 23 ) . - pubmed
Visual word form processing deficits driven by severity of reading impairments in children with developmental dyslexia . - pubmed
Here , we report fMRI data from a multicentre study with 140 children in primary school ( 7.9 - 12.2 years ; 55 children with dyslexia , 73 typical readers , 12 intermediate readers ) . - pubmed
BACKGROUND : One of the most feared complications of rhytidectomy is the formation of hematoma and seroma , which may harm patients ' health and compromise the surgical outcome . - pubmed
Time - course comparison of pulmonary inflammation induced by intratracheal instillation of four different nickel oxide nanoparticles in male Fischer rats . - pubmed
The NiOs were suspended in purified water and instilled once intratracheally into male F344 rats ( 12 weeks old ) at 0 ( vehicle control ) , 0.67 , 2 , and 6 mg / kg body weight . - pubmed
To develop intravital criteria of the reperative processes following myocardial infarction , clinical , biochemical and morphological parallels were traced in 62 patients dying of myocardial infarction after different periods following the onset of the disease . - pubmed
A second component of Australian tiger snake venom was also found to be myotoxic . - pubmed
Notexin could be neutralized by incubation with tiger snake antivenene ; the simultaneous injection of antivenene with notexin did not afford complete protection against muscle damage . - pubmed
Indoprofen , a new non - steroidal anti - inflammatory drug , in the treatment of osteoarthrosis : report on a multi - centre study in 1629 patients . - pubmed
A multi - centre trial was carried out in 1629 patients with osteoarthrosis in 233 clinical centres to investigate the therapeutic efficacy and tolerability of indoprofen in this clinical condition . - pubmed
The results indicate that sera from a large proportion of patients with adenocarcinomas of the digestive tract , pancreas , and breast are capable of inhibiting the above inactivation , whereas most normal sera do not inhibit . - pubmed
This phenomenon may be implicated in the pathogenesis of human breast cancer . - pubmed
Clinical course , early and late complications as well as treatment of ophthalmic zoster in 70 hospitalized patients are presented . - pubmed
This work investigated the pattern of ACTH and cortisol response to hypoglycemia in goats and the effect of dexamethasone on this response . - pubmed
It is suggested that there is no value in the routine performance of liver function tests in patients with epilepsy . - pubmed
Stress proteins and cross - protection by heat shock and salt stress in Bacillus subtilis . - pubmed
We report here genetic recombination between 2 USDA - licensed vaccine strains of pseudorabies virus co - inoculated into swine . - pubmed
Co - inoculation resulted in the creation of novel strains of pseudorabies virus containing negative immunologic markers with restored virulence genes . - pubmed
Plaque - purified recombinant progeny viruses were found in 2 litters of pigs in which both strains were co - inoculated IM , a litter in which both strains were co - inoculated oronasally , and a litter in which the conventionally attenuated strain was inoculated oronasally and the genetically engineered strain was inoculated IM . - pubmed
The creation , spread , and potential misdiagnosis of these types of recombinant strains could disrupt control and eradication programs that are based on the serologic identification of swine infected with potentially virulent strains of pseudorabies virus . - pubmed
However , when injected in patients with LA , IVIg do not seem to operate by this mechanism of action . - pubmed
Electric field stimulation of human osteosarcoma - derived cells : a dose - response study . - pubmed
In vitro electrical stimulation of human osteosarcoma - derived cells resulted in increased cell adherence and current directed cell migration . - pubmed
For the first time R - bodies are described in a new strain 44T1 of Pseudomonas aeruginosa . - pubmed
The echocardiographic features and management of 10 children with right heart thrombus ( RHT ) are presented . - pubmed
The thrombus was detected in the right atrium ( five patients ) , in the right ventricle ( three ) , on the tricuspid valve or within the inferior vena cava , the superior vena cava , or its extension following Senning 's operation for transposition of great arteries ( TGA ) . - pubmed
In two of three patients with anatomically normal heart , the thrombus occurred as a complication of a ventriculoatrial and a lymphovenous shunt system . - pubmed
Transplantation of Lewis lung carcinoma in mouse uterus . - pubmed
Earlier studies have shown that pregnant and nonpregnant mammalian uteri respond differently to tumor cell invasion , colonization and metastasis , but the biological basis of such differential uterine response has not been clarified . - pubmed
In the present study we have investigated the role of the metastatic potential of the tumor in the differential response of different stages of mouse uteri , using a highly metastatic tumor . - pubmed
In the tumor cell - treated animals , despite an early and uniform invasion the patterns of tumor cell colonization and metastasis differed remarkably from the pregnant to nonpregnant uteri . - pubmed
Though 40 % of the pregnant animals had tumor cells in the uteri , none had metastasis in other organs . - pubmed
These results indicate the refractory nature of both the pregnant and nonpregnant mouse uteri to the survival and colonization of LLC cells , but the mechanisms by which the tumor cells are eliminated differ between these two types of uteri . - pubmed
Chronic myeloid leukemia ( CML ) was diagnosed in a 19 - year - old man in 1961 , and the disease remained in chronic phase , with occasional exacerbations , for 27 years . - pubmed
Rearranged Epstein - Barr virus genomes and clonal origin in nasopharyngeal carcinoma . - pubmed
Epstein - Barr virus ( EBV ) is known to be associated with two malignant diseases , nasopharyngeal carcinoma ( NPC ) and endemic Burkitt ' s lymphoma . - pubmed
In this study , the genomes of EBV in biopsy specimens from 4 NPC patients in Japan were analyzed using Southern blot hybridization . - pubmed
The animal model employed here might be suitable for studying the effects of hypoxia in newborns and children during chest operations involving the descending aorta . - pubmed
Local administration was performed for patients with skin malignancy , and bladder and hepatic carcinoma . - pubmed
Among 239 cases eligible for evaluation ( 144 cases treated by systemic administration and 95 cases by local injection ) , complete response was observed in one case each of renal cell carcinoma , malignant lymphoma and mycosis fungoides , all treated by systemic administration . - pubmed
Fever was observed in 89 % of the cases treated by systemic administration . - pubmed
Conditions for efficient regeneration in mutant strains of the doxorubicin - producing organism Str . - pubmed
The lower control rate in patients who had surgery alone could be due ( in part ) to inadequate surgery at the primary site ( 42 % local excision ) and lack of neck dissection ( 35 % for SA vs. 77 % for S + R ) . - pubmed
Postoperative radiation therapy to the primary site and neck is shown to effectively reduce local recurrence in patients with oral cavity and oropharynx cancer , regardless of surgical margins . - pubmed
Ambulatory nursing of patients with infections ] . - pubmed
[ Analgesia for dental interventions in ischemic heart disease patients with intolerance to local anesthetic preparations ] . - pubmed
Primary zinc deficiency conditions of the magnitude seen in this study and in this - age rat did not appear to alter serum thyroid hormone levels or organ / glandular function . - pubmed
For patients with less frequent recurrent HSV episodes involving localised and accessible sites topical acyclovir cream may be preferred to the equally effective but more expensive oral acyclovir . - pubmed
The in vitro DNA - intercalator ellipticine and five of its derivatives have been investigated for some of their physiological effects on several Escherichia coli strains . - pubmed
Sialic acid ( N - acetylneuraminic acid ) in the synovial fluid and serum of patients with inflammatory and non - inflammatory joint disease . - pubmed
We reviewed our experience over the past six years with retroperitoneal inflow procedures ( aortofemoral and iliofemoral bypass grafts ) in high - risk patients with aortoiliac occlusive disease . - pubmed
Twenty percent of the patients were diabetic , 80 % were smokers , 40 % had heart disease , 54 % had hypertension , and 25 % had symptomatic chronic obstructive pulmonary disease . - pubmed
The serum concentration of salbutamol was determined in 29 pregnant women during oral treatment ( 4 mg five times per day ) and in seven during intravenous infusion ( 6 - 30 micrograms / min ) because of premature labour . - pubmed
Deficiency of the fourth component of complement in man . - pubmed
Lymphographic findings in a series of 258 patients with tumors of the testes . - pubmed
[ Acute basophil leukemia with cutaneous and osseous manifestations revealing saturnism in young children ] . - pubmed
The rehabilitation of long - stay schizophrenic patients . - pubmed
[ The effect of vaporization with thermal sulfurous water on phospholipids in the broncho - alveolar lavage solution following hypobaric hypoxia in the rat ] . - pubmed
We have studied , in the rat , the action of a vaporization with sulphurous water from Bagneres de Luchon on the surfactant modifications caused by hypoxia . - pubmed
So we can conclude that a vaporization with sulphurous water had a protective action against hypoxia on the broncho - alveolar lavage of rat lung . - pubmed
[ Hormone - dependent enhancement of malignant phenotype in cells infected with mouse mammary tumor virus ( MMTV ) , and role of antigen transduction in this process ] . - pubmed
Mouse mammary tumor virus ( MMTV ) is known to infect heterologous cells but it does not appear that it alters their growth or morphological characteristics . - pubmed
Djungarian hamster mammary tumor cells infected with MMTV were found to increase the ability of the above cells to grow in semi - solid media . - pubmed
[ Effects of medial preoptic area stimulation on the midbrain central gray related to lordosis in female rats ] . - pubmed
These data suggest that in patients with advanced Parkinson ' s disease , L - dopa administration results in a smaller increase and a shorter duration of elevation in striatal dopamine concentration than in controls . - pubmed
These observations support the hypothesis that the " wearing - off " phenomenon that occurs during the treatment of patients with Parkinson ' s disease occurs as a consequence of a reduction in the rate of conversion of L - dopa to dopamine and perhaps diminished capacity for the storage of dopamine . - pubmed
Level and temporal pattern of naturally cytolytic cells during acute Graft - versus - Host Disease ( GVHD ) in the rat . - pubmed
Acute lethal GVHD was produced in either newborn or adult ( DA x LEW)F1 rats by iv injection of LEW spleen and lymph node ( LN ) cells . - pubmed
At 7 , 14 , and 21 days after cell injection , the ability of non - adherent mononuclear cells from the LN , spleen , peripheral blood lymphocytes ( PBL ) , marrow , and thymus to kill 51Cr - labeled dog ( DT-5 ) lymphoma , and undifferentiated sarcoma ( 11031 ) or human ( HUS-2 ) sarcoma cells in vitro was determined . - pubmed
Cervical curve depth ( CCD ) was radiographically evaluated in 35 patients who presented with cervical hypolordosis or kyphosis ( CH / K ) . - pubmed
The blood glucose level of rats with streptozotocin ( STZ)-induced diabetes has been found to be normalized by administration of vanadyl or vanadate complexes . - pubmed
VPA was also effective for normalizing the blood glucose level of STZ - induced diabetic rats when given intraperitoneally or orally . - pubmed
Role of sodium - hydrogen exchange in the proliferation of immortalised lymphoblasts from patients with essential hypertension and normotensive subjects . - pubmed
Similarly , expression of TGF - alpha mRNA and peptide has been shown to occur in various human lung carcinomas in vivo and in vitro . - pubmed
In an 8 - week , placebo - controlled multicenter study , the efficacy of dose levels of simvastatin 2.5 , 5 , 10 , 20 , and 40 mg was evaluated in 166 patients with hypercholesterolemia , of whom 163 completed the trial . - pubmed
The ability of oxidative stress to induce apoptosis ( programmed cell death ) , and the effect of Trolox , a water soluble vitamin E analog , on this induction were studied in vitro in mouse thymocytes . - pubmed
Two patients with schizophrenia had markedly abnormal neuroimaging studies ; one was found to have a large , cystic cavum vergae , while the other demonstrated complete agenesis of the septum pellucidum with a monoventricular system . - pubmed
Teaching was carried out by a Diabetes Nurse Educator within primary care health centres ( 141 patients ) and a hospital diabetes clinic ( 17 patients ) . - pubmed
Glucose-6 - phosphate isomerase deficiency associated with nonspherocytic hemolytic anemia in the mouse : an animal model for the human disease . - pubmed
The first two mutations causing hereditary glucose-6 - phosphate isomerase ( GPI ) deficiency associated with chronic nonspherocytic hemolytic anemia in nonhuman mammals are described in the mouse . - pubmed
In comparison with wild type , heterozygous individuals exhibited neither hematologic differences nor alterations of other physiologic parameters , including plasma concentration of glucose , pyruvate and lactate , body weight , organo - somatic indices of liver , lung , kidney , spleen , and heart , as well as viability . - pubmed
Homozygous anemic mice showed hepatosplenomegaly and typical adaptations to hypoxia , such as an elevated heart - somatic index and , for one mutant line , an enhanced lung - somatic index . - pubmed
Further , these animals were characterized by a marked reduction of body weight and an increase of lethality both correlated with the degree of enzyme deficiency in tissues . - pubmed
The latter findings were attributed to a reduced glycolytic capability of the whole organism caused by the enzyme defect in tissues , rather than representing secondary consequences of GPI deficiency in erythrocytes . - pubmed
The similarity in physicochemical and kinetic properties of the mutant murine proteins reported earlier with those of allozymes found in human GPI deficiency , as well as the comparable metabolic and physiologic consequences of this enzyme defect in mice and humans support that these murine mutants are excellent animal models for the human disease . - pubmed
METHODS : We evaluated maternal reporting of signs and symptoms 2 and 4 weeks after diagnosis among 271 Egyptian children & lt ; 5 years old . - pubmed
Children with ARI were evaluated by physical examination , chest radiography , and pulse oximetry , and were alternately assigned for a maternal interview about the episode 14 or 28 days later . - pubmed
Outcome of respiratory symptoms after antireflux surgery on patients with gastroesophageal reflux disease . - pubmed
DESIGN : A case series of patients with GERD and respiratory symptoms undergoing fundoplication from 1987 to 1994 at a tertiary care university hospital . - pubmed
PATIENTS : Of 118 patients undergoing fundoplication for cardinal symptoms of GERD , 63 had respiratory symptoms . - pubmed
RESULTS : Respiratory symptoms were present in 53 % ( 63/118 ) of patients with GERD . - pubmed
Abnormalities of esophageal motility were present in 34 % ( 17/50 ) of the patients , and these were significantly more common in patients who did not experience relief of their respiratory symptoms ( 9/12 vs 8/38 , chi 2 = 9.54 , P = .002 ) . - pubmed
CONCLUSIONS : Respiratory symptoms are common in patients with GERD . - pubmed
Effect of left and right lateral decubitus positions on Doppler mitral flow patterns in patients with severe congestive heart failure . - pubmed
Patients with severe congestive heart failure ( SCHF ) complain of increasing dyspnea when adopting left lateral decubitus ( LLD ) position that improves when turning over to the right lateral decubitus ( RLD ) position ( trepopnea ) . - pubmed
This study analyzes the effect of RLD and LLD positions on LV filling pattern assessed by Doppler echocardiography in patients with SCHF . - pubmed
Seventeen men and seven women ( aged 56.22 + /- 18.52 years ) with SCHF in New York Heart Association functional class III - IV and nine normal control subjects ( eight men and one woman aged 56.96 + /- 18.14 years ) were studied . - pubmed
The objective of the present work was to study the effects of tic disorder ( TD ) and hyperactivity ( HA ) on slow cortical potentials in children with combined TD + HA symptoms . - pubmed
Four groups of children ( n = 10/11 in each group ) were studied : healthy controls , pure TD , pure attention deficit hyperactivity disorder ( ADHD ) , and combined tic and hyperactivity symptoms . - pubmed
Nevertheless , deviant patterns of scalp distribution were found for pure ADHD patients , which suggested an inefficiency in involving the adequate task - related areas . - pubmed
Human infection with the pathogenic tissue nematode Onchocerca volvulus may result in a spectrum of clinical manifestations or in a putatively immune condition . - pubmed
It was found that Zn pretreatment ( I mg / kg body weight as ZnSO4 ) has a unique inhibitory effect on IDDM development in MT - null mice in contrast to no marked effect in control ( C57BL/6J ) mice , suggesting that Zn ions free from MT molecules exerted this protective effect . - pubmed
The highest Zn dose ( 10 mg / kg body weight ) fully suppressed development of hyperglycaemia in both types of mice . - pubmed
Infection by hepatitis C viruses ( HCVs ) is a serious medical problem with no broadly effective treatment available for the progression of chronic hepatitis . - pubmed
Male BXSB mice , unlike female BXSB , develop a severe early onset lupus - like disease that has been linked to an intrinsic B cell defect . - pubmed
A less marked and later lymphocytopenia was also shown in subjects affected by chronic renal insufficiency ( 2907 + /- 726 t 0 ; 1944 + /- 512 t 180 minutes , p & lt ; 0.005 ) . - pubmed
Conyza floribunda , Eupatorium articulatum , Bonafousia longituba , Bonafousia sananho , Tagetes pusilla and Piper lenticellosum extracts showed a significant antiinflammatory activity in vivo in the carrageenan - induced paw oedema model in mice . - pubmed
Re : " Tobacco as a cause of lung cancer : some reflections " . - pubmed
RESULTS : Twenty - eight patients ( 2.5 % ) had intraoperative complications related to the vena cava preservation technique , which were treated during the operation . - pubmed
Eleven patients ( 1 % ) had early postoperative complications ( first week ) , the most frequent ( nine cases ) being an acute Budd - Chiari syndrome in the first 48 hr . - pubmed
Three patients developed symptoms of massive ascites between 2 and 3 months ( late postoperative complications ) , with patency of the retrohepatic cava verified by cavography . - pubmed
This chronic Budd - Chiari syndrome was controlled in all patients with diuretics . - pubmed
Anti - inflammatory activity of phycocyanin extract in acetic acid - induced colitis in rats . - pubmed
The anti - inflammatory effect of c - phycocyanin extract was studied in acetic acid - induced colitis in rats . - pubmed
was administered 30 min gbefore induction of colitis with enema of 1 ml of 4 % acetic acid per rat . - pubmed
Human astrovirus ( HAstV ) is a significant cause of acute diarrhea among children , resulting in outbreaks of diarrhea and occasionally in hospitalization . - pubmed
Improved detection methods for eight antigenic types of HAstV and studies assessing the frequency and severity of HAstV diarrhea have further defined the impact of HAstV infections in children . - pubmed
However , frequent coinfection of HAstV with rotavirus and caliciviruses in childhood diarrhea complicates the epidemiology . - pubmed
STUDY OBJECTIVES : Respiratory muscle strength has been shown to be reduced in patients with chronic heart failure . - pubmed
The purpose of this prospective study was to determine whether long - term therapy with the angiotensin - converting enzyme ( ACE ) inhibitor perindopril improves respiratory muscle strength in patients with chronic heart failure . - pubmed
PATIENTS AND METHODS : Eighteen patients with stable chronic heart failure were administered perindopril , 4 mg / d , in addition to their standard therapy for a period of 6 months . - pubmed
A 7 - month - old , neutered female Labrador Retriever was evaluated for tetraparesis and subtle cerebellar dysfunction . - pubmed
This disease and its relation to similar human heritable leukodystrophies are discussed . - pubmed
DESIGN : Two hundred and sixty - eight pregnant women with type 1 diabetes mellitus were recruited . - pubmed
Latent infection of human ganglia with Varicella - Zoster virus ( VZV ) is characterized by a highly restricted pattern of viral gene expression . - pubmed
At the later time points after infection the RNA transcripts expressed most frequently were those for VZV genes 21 , 62 , and 63 . - pubmed
Management of hydrocephalus in pediatric patients with posterior fossa tumors : the role of endoscopic third ventriculostomy . - pubmed
OBJECT : The authors undertook a study to evaluate the effectiveness of endoscopic third ventriculostomy in the management of hydrocephalus before and after surgical intervention for posterior fossa tumors in children . - pubmed
METHODS : Between October 1 , 1993 , and December 31 , 1997 , a total of 206 consecutive children with posterior fossa tumors underwent surgery at Hjpital Necker - Enfants Malades in Paris . - pubmed
The medical records and neuroimaging studies of the remaining 196 patients were reviewed and categorized into three groups : Group A , 67 patients with hydrocephalus present on admission in whom endoscopic third ventriculostomy was performed prior to tumor removal ; Group B , 82 patients with hydrocephalus who did not undergo preliminary third ventriculostomy but instead received conventional treatment ; and Group C , 47 patients in whom no ventricular dilation was present on admission . - pubmed
There were no significant differences between patients in Group A or B with respect to the following variables : age at presentation , evidence of metastatic disease , extent of tumor resection , or follow - up duration . - pubmed
In patients in Group A , however , more severe hydrocephalus was demonstrated ( p & lt ; 0.01 ): the patients in Group C were in this respect different from those in the other two groups . - pubmed
Ultimately , there were only four patients ( 6 % ) in Group A compared with 22 patients ( 26.8 % ) in Group B ( p = 0.001 ) in whom progressive hydrocephalus required treatment following removal of the posterior fossa tumor . - pubmed
The other six patients ( 7.3 % ) were treated by endoscopic third ventriculostomy after tumor resection . - pubmed
In Group C , two patients ( 4.3 % ) with postoperative hydrocephalus underwent endoscopic third ventriculostomy . - pubmed
Although the authors acknowledge that the routine application of third ventriculostomy in selected patients results in a proportion of patients undergoing an " unnecessary " procedure , they believe that because patients ' postoperative courses are less complicated and because the incidence of morbidity is low and the success rate is high in those patients with severe hydrocephalus that further investigation of this protocol is warranted . - pubmed
Surgery for giant intracranial aneurysms not operable using standard neurosurgical techniques was performed in 8 patients . - pubmed
PURPOSE : The aim of this study was to investigate changes in quality of life ( QOL ) among medically inoperable Stage I non - small - cell lung cancer ( NSCLC ) patients treated with curative radiotherapy . - pubmed
PATIENTS AND METHODS : The study sample was composed of 46 patients irradiated for Stage I NSCLC . - pubmed
None of the locally treated patients developed regional recurrence . - pubmed
Significantly higher levels of dysphagia , which persisted up to 12 months , were observed in those in which the regional lymph nodes were treated , as compared to the locally treated patients . - pubmed
Taking into account the low incidence of regional recurrences after local irradiation , the higher incidence and severity of radiation - induced changes , and the higher levels of dysphagia persisting up to 12 months , local irradiation of the primary tumor without elective irradiation of the regional lymph nodes may be the most appropriate treatment for patients with small , peripherally located tumors . - pubmed
OBJECTIVE : The purpose of this study was to investigate the relationship between blood pressure that is measured with the automated blood pressure monitor , Omron HEM-705CP ( Omron Corporation , Tokyo , Japan ) , and mercury sphygmomanometry in normotensive and preeclamptic pregnant women . - pubmed
After routine mercury blood pressure recordings that were taken by midwives , women with preeclampsia ( n = 45 women ) measured their own blood pressure using an Omron HEM-705CP monitor ( n = 212 recordings ) . - pubmed
METHODS : Argon plasma coagulation was applied in 13 children ( age 0.05 - 17 years ; median 3 years ) with significant comorbid conditions including immunosuppression , chemotherapy , acute or chronic organ failure , and coagulopathy . - pubmed
Blood loss and transfusion requirement were reduced in 3 of the other 4 patients . - pubmed
Complications occurred in 2 of 13 patients and included submucosal argon gas and scar formation . - pubmed
A male patient underwent hepatectomy for removal of metastatic tumors from colon cancer . - pubmed
CASE PRESENTATION : A 34 - year - old man had a sudden onset of severe headache . - pubmed
The patient had an uneventful postoperative course and his neurologic symptoms were improved . - pubmed
BACKGROUND : Porphyromonas gingivalis , a key pathogen in periodontitis , is able to adhere to and invade the pocket epithelium . - pubmed
gingivalis serotypes ( 6 capsular types and non - encapsulated strains ) was compared on in vitro cultured epithelial monolayers from periodontal pockets of patients with periodontitis . - pubmed
gingivalis to human periodontal pocket epithelial cells . - pubmed
Heterotopic ossification in the ischemic kidney of the rabbit , rat and guinea pig . - pubmed
CONCLUSION : The observed decreasing trend in oral cancers in Indian men may be attributed to a decrease in the usage of pan and tobacco . - pubmed
Oats , antioxidants and endothelial function in overweight , dyslipidemic adults . - pubmed
OBJECTIVE : To determine effects of oat and antioxidant vitamin ( C 500 mg , E 400 IU ) ingestion on endothelial function in overweight , dyslipidemic adults . - pubmed
Atypical antipsychotics are not well studied in the treatment of elderly patients with functional psychosis . - pubmed
Secondary end points included changes in mean serum creatinine and estimated GFR ( Cockroft and Gault , CG ) over time , incidence of infection , cardiovascular risk factors ( blood pressure , cholesterol ) , graft and patient survival rates , as well as incidence of biopsy - proven chronic allograft nephropathy ( CAN ) . - pubmed
Biopsy - proven CAN was diagnosed in 2 control patients ( 10 % ) at 6 to 8 months ' posttransplant . - pubmed
Twenty - one patients were treated in the Pacific Voice Clinic with trancutaneous injection of CaHA for vocal cord paralysis ( n = 19 ) and vocal scarring ( n = 2 ) . - pubmed
We report here that , in C57BL / 6 mice , the recruitment of naive lymphocytes is impaired in LNs draining a B16 melanoma tumor . - pubmed
Cabbage and wheat was more susceptive to AlCl3 toxicity under acid than under neutral condition , while radish was in adverse . - pubmed
MATERIALS AND METHODS : Thirty - two pregnant patients with the diagnosis of malignancy were followed . - pubmed
CONCLUSION : The cancer treatment took into full consideration the specific condition of each pregnant patient . - pubmed
Nine patients ( 10 eyes ) with complicated , refractory primary and secondary open - angle glaucoma are discussed . - pubmed
An elderly woman presented with her third episode of back pain , fever and neurological deficits . - pubmed
Herpes zoster virus ( HZV ) reactivation is commonly reported in elderly or immune compromised patients . - pubmed
In a 43 - year - old man admitted due to episodes of syncope , the diagnosis of LD was delayed -- after pacemaker implantation -- when he developed joint and neurological symptoms . - pubmed
In the second case of a 26 - year - old woman , presenting on admission with fatigue and flu - like symptoms , ECG showed CHB with a stable escape rhythm of about 52 / min . - pubmed
Malaria has been a major selective force on the human population , and several erythrocyte polymorphisms have evolved that confer resistance to severe malaria . - pubmed
A 76 - year - old man was referred to our hospital because of memory impairment . - pubmed
After 6 months of treatment , the scores on verbal fluency ( animals and vegetables/60 seconds ) and frontal assessment battery of the patient improved despite no significant changes on the Mini - Mental State Examination and Alzheimer ' s Disease Assessment Scale . - pubmed
Systemic reaction to leucovorin in a child with lymphoblastic lymphoma suggestive of hypersensitivity . - pubmed
Honokiol is an active compound purified from magnolia that has been shown to induce cell differentiation , apoptosis , and anti - angiogenesis effects , as well as an enhancement in tumor growth delay in combination with chemotherapeutic agents in several mouse xenograft models . - pubmed
For an in vivo study , Lewis lung carcinoma - bearing C57BL / 6 mice were treated with either liposomal honokiol at 25 mg / kg or 5 Gy of single tumor radiation , or a combination of both over 12 days of treatment . - pubmed
Amino acid biosynthesis deficiency in bacteria associated with human and animal hosts . - pubmed
METHODS : Thirty - two consecutive patients with pathologically proven hilar cholangiocarcinomas were evaluated by both low mechanical index CEUS and CECT . - pubmed
OBJECTIVES : To make a contribution to the treatment modality of larynx cancer , we evaluated our surgical outcomes of the patients with larynx cancer and their quality of life in the postoperative period . - pubmed
PATIENTS AND METHODS : Forty - three patients ( 38 males , 5 females ; mean age 57.6 years ; range 34 to 84 years ) with larynx cancer were included in this retrospective clinical study . - pubmed
The patients were evaluated with respect to age , sex , smoking , alcohol consumption , localization - differentiation - stage of the tumor , surgery and RT , postoperative complications and survival . - pubmed
RESULTS : The most frequent postoperative complication was pharyngocutaneous fistula ( 41.3 % ) , which occurred only in TL / NTL patients . - pubmed
We emphasize that multi - institutional prospective quality of life studies comparing different treatment methods for similar stage tumors are essential in defining the optimal management strategy in patients with larynx cancer . - pubmed
A 45 - year - old woman presented with left - side pulsating tinnitus , autophony and disequilibrium . - pubmed
Furthermore , we show that beta toxin strongly stimulates biofilm formation in vivo as demonstrated by a role in causation of infectious endocarditis in a rabbit model . - pubmed
Although there is still no consensus on the treatment of individuals with asymptomatic hyperuricemia , it is time to reappraise potential approaches for these subjects with regard to prevention of hypertension and related renal and cardiovascular complications . - pubmed
In this study , ischemia induction for 18 min in male New Zealand White rabbits resulted in the highest percentage ( 80 % ) of biphasic paraplegic outcome assessed by Tarlov 's score . - pubmed
With improvement in leukemia therapy , central nervous system ( CNS ) tumors are the leading cause of cancer mortality in children and the most expensive of all human neoplasms to treat . - pubmed
Therefore , considering the complex physiology of solid tumors and in order to inform simulations well , we did experiments on Balb / c mice using non - invasive fluorescence spectroscopy to have a feedback of protoporphyrin IX ( PpIX ) concentration in tumor just before irradiation and during treatment . - pubmed
Atrial fibrillation , the most common cardiac complication of hyperthyroidism , occurs in an estimated 10 % to 25 % of overtly hyperthyroid patients . - pubmed
Herein , we review the medical literature and examine the evidence behind the recommendations in order to determine the best approach to thromboembolic prophylaxis in patients who have atrial fibrillation that is associated with hyperthyroidism . - pubmed
METHODS : Eighteen cases with left peripheral facial paralysis were randomly divided into a Hegu group , a Dicang group and a Houxi group , 6 cases in each group . - pubmed
PATIENTS / METHODS : We studied 241 patients , including 162 after ischemic stroke and 79 after transient ischemic attack ( TIA ) , recruited 6 months to 4 years ( median , 36 months ) after the events . - pubmed
After starting of prednisone treatment anemia , thromocytopenia and the patient 's performance status rapidly improved . - pubmed
Linkage study of embryopathy - polygenic inheritance of diabetes - induced skeletal malformations in the rat . - pubmed
We developed an inbred rat model of diabetic embryopathy , in which the offspring displays skeletal malformations ( agnathia or micrognathia ) when the mother is diabetic , and no malformations when she is not diabetic . - pubmed
We contrasted the fetal outcome in inbred Sprague - Dawley L rats ( 20 % skeletal malformations in diabetic pregnancy ) with that of inbred Wistar Furth rats ( denotedW , no skeletal malformations in diabetic pregnancy ) . - pubmed
We conclude that the genetic involvement in rodent diabetic embryopathy is polygenic and predisposing for congenital malformations . - pubmed
Five patients with extensive lower abdominal wall disruption following traumatic injuries or infection were treated using a novel flap for functional reconstruction . - pubmed
The innervated TFL osteomyocutaneous flap is an ideal option for lower abdominal reconstruction in patients with complex abdominoperineal defects with loss of bony integrity . - pubmed
METHODS : Corneas of patients with Fuchs ' dystrophy were examined prospectively before and at intervals through 2 years after DSEK . - pubmed
Protective effects of vitamins E , B and C and L - carnitine in the prevention of cisplatin - induced ototoxicity in rats . - pubmed
CONCLUSION : Vitamins B , E and C and L - carnitine appear to reduce cisplatin - induced ototoxicity in rats . - pubmed
The use of such additional treatments to decrease cisplatin - induced ototoxicity in humans is still under discussion . - pubmed
STUDY OBJECTIVES : The purpose of this study was to determine if subjects with moderate - to - severe obstructive sleep apnea would experience increasing treatment effect when a tongue retention component was added to a mandibular repositioning appliance . - pubmed
PATIENTS : Forty - four sequentially recruited patients with moderate - to - severe obstructive sleep apnea . - pubmed
PATIENTS AND METHODS : 60 patients with visceral obesity were randomly assigned to either receive 9 g of L - arginine or placebo for 3 months . - pubmed
OBJECTIVE : The aim of our study was to examine the 30 - day and 1 - year survival rate for patients undergoing percutaneous coronary artery intervention ( PCI ) of unprotected left main ( ULM ) stenosis by the presence ( acute myocardial infarction [ AMI ] group ) or absence ( non - AMI group ) of AMI at the time of hospital admission . - pubmed
METHODS : We retrospectively reviewed 64 patients undergoing PCI of ULM stenosis at our regional heart institute between 2000 and 2008 . - pubmed
RESULTS : Thirty - six men and 28 women underwent PCI for ULM stenosis . - pubmed
Thirty - three patients ( 51.6 % ) presented with AMI . - pubmed
CONCLUSIONS : We found that AMI at presentation was significantly associated with higher mortality in patients undergoing ULM stenting . - pubmed
Perseverative behavior in rats with methamphetamine - induced neurotoxicity . - pubmed
Infection of Mexican lime trees ( Citrus aurantifolia L. ) with the specialized bacterium " CandidatusPhytoplasma aurantifolia " causes witches ' broom disease . - pubmed
Respiratory disease due to current egg drop syndrome virus in Pekin ducks . - pubmed
Severe acute respiratory symptoms with coughing , dyspnea , and gasping were reported in two flocks of 9 - day - old Pekin ducklings from different provinces . - pubmed
Reproducibility of microvolt T - wave alternans in patients with ischemic heart disease . - pubmed
Forty - two postmenopausal women with osteoporosis and thirty seven age and BMI - matched healthy postmenopausal women were included in the study . - pubmed
A comparison of spectral quality in magnetic resonance spectroscopy data acquired with and without a novel EPI - navigated PRESS sequence in school - aged children with fetal alcohol spectrum disorders . - pubmed
Association between bioimpedance analysis parameters and left ventricular hypertrophy in peritoneal dialysis patients . - pubmed
In this study , we aimed to determine the impact of blood pressure measurements and volume status determined by bioelectrical impedance analysis ( BIA ) measurements over left ventricular hypertrophy ( LVH ) in PD patients . - pubmed
METHODS : Thirty - one prevalent PD patients were enrolled . - pubmed
Patients with a documented cardiovascular disease and uncontrolled hypertension were excluded . - pubmed
Fifty - eight percent of patients had LVH . - pubmed
CONCLUSIONS : We want to underline that , besides maintaining residual renal function , strict blood pressure control , particularly diastolic blood pressure , and avoiding hypervolemia and abdominal obesity should be main clinical goals in follow - up of PD patients in order to prevent LVH progression . - pubmed
33 volunteers drove for 90 min on a rural road during the afternoon and night in an instrumented car , while electroencephalography and electrooculography and lane departures were recorded continuously and subjective ratings of sleepiness were made every 5 min ( Karolinska Sleepiness Scale - KSS ) . - pubmed
Synthesis and cytotoxic activity evaluation of novel arylpiperazine derivatives on human prostate cancer cell lines . - pubmed
The in vitro cytotoxic activities of all synthesized compounds against three human prostate cancer cell lines ( PC-3 , LNCaP , and DU145 ) were evaluated by a CCK-8 assay . - pubmed
However , these compounds also exhibited cytotoxicity towards human epithelial prostate normal cells RWPE-1 . - pubmed
infections in horses from northern and central Kazakhstan . - pubmed
A cross - sectional survey was performed to obtain current data on the gastrointestinal myiasis of horses in the provinces of Kostanay , Akmola and Karagandy , northern and central Kazakhstan . - pubmed
Evaluation of nanoformulated therapeutics in an ex - vivo bovine corneal irritation model . - pubmed
METHODS : The bovine cornea obtained were subjected to the 0.5N NaOH insult that induced alkali burn and inflammation as observed in the in vivo situation . - pubmed
METHODS : Thirty - two patients with primary ACL deficiency were analysed by a navigation system immediately before and after each of the two reconstructions . - pubmed
UNBLOCK : an open - label , dose - finding , pharmacokinetic and safety study of bivalirudin in children with deep vein thrombosis . - pubmed
PATIENTS / METHODS : The UNBLOCK ( UtilizatioN of BivaLirudin On Clots in Kids ) study was an open - label , single - arm , dose - finding , pharmacokinetic , safety and efficacy study of bivalirudin for the acute treatment of deep vein thrombosis ( DVT ) in children aged 6 months to 18 years . - pubmed
At 48 - 72 h , nine ( 50 % ) patients had complete or partial thrombus resolution , increasing to 16 ( 89 % ) at 25 - 35 days . - pubmed
CONCLUSIONS : Bivalirudin demonstrated reassuring safety and noteworthy efficacy in terms of early clot resolution in children and adolescents with DVT . - pubmed
Although a widely available and familiar monitoring tool , the APTT correlates poorly with plasma bivalirudin concentration , possibly limiting its utility in managing pediatric patients receiving bivalirudin for DVT . - pubmed
Lamotrigine ( LTG ) is commonly used to control seizure in epilepsy patients and with referenced therapeutic windows in clinical practice . - pubmed
This study is to identify and characterize the function of genetic variants that influence the trough concentrations of LTG in epilepsy patients following monotherapy regimen ( 37.5 - 250 mg / d ) . - pubmed
Our findings have important implications for the rational overcoming of drug resistance in individual leukemia patients . - pubmed
Methodology and technique advancements facilitated the early diagnosis of AD leading to a shift toward preclinical AD stages investigation in order to delay the disease onset in individuals at risk for AD . - pubmed
Due to these promising results , an emerging field of studies is currently investigating the efficacy of interventions addressing different lifestyle habits in cognitive intact elderly individuals as a potential preventive strategy against AD onset . - pubmed
PATIENTS AND METHODS : In a prospective study of 55 patients ( 30 m , 25 f , age 16 - 77 years ) with a chronic rhinosinusitis with or without polyps combined with a deformity of the outer nose we performed a FESS together with a SRP using a closed or open approach . - pubmed
Effect of chemoradiotherapy on nutrition status of patients with nasopharyngeal cancer . - pubmed
We aimed to assess the effect of chemoradiotherapy on the nutritional status of patients with nasopharyngeal cancer ( NPC ) and to detect the risk factors for poor nutrition status in NPC patients after radiotherapy . - pubmed
A total of 104 NPC patients participated in this clinical observational study . - pubmed
After radiotherapy , 20.19 % of patients had more than 10 % weight loss . - pubmed
Radiotherapy affects the nutritional status of NPC patients . - pubmed
OBJECTIVE : To retrospectively analyze the clinical , radiologic , and endoscopic characteristics of small bowel cancer patients in Thailand 's Siriraj Hospital . - pubmed
MATERIALS AND METHODS : This retrospective analysis included 185 adult patients ( 97 men , 88 women ; mean age = 57.6 + -14.9 ) with pathologically confirmed small bowel cancer diagnosed between January 2006 and December 2013 . - pubmed
RESULTS : Of the 185 patients analyzed , gastrointestinal stromal tumor ( GIST ) was the most common diagnosis ( 39.5 % , n=73 ) . - pubmed
RESULTS : A 41 - year - old woman was referred with a 2 - week history of decreased vision and scotoma in the left eye . - pubmed
BACKGROUND : Human immunodeficiency virus ( HIV ) Rapid diagnostic Test ( RDT ) kits are the preferred assays for HIV testing in many countries . - pubmed
Little is known about the diagnostic characteristics of First Response HIV-1 - 2 RDT kit , used as a single test kit in national HIV prevention and control programmes . - pubmed
BACKGROUND : Patients with bilateral hip disease may undergo same - day or staged bilateral total hip arthroplasty ( THA ) . - pubmed
Patients with subsequent PJI were identified . - pubmed
In this regard , somatic genetic evaluation of tumors is useful in not only predicting response to initial targeted therapies but also in anticipating and guiding therapy after the development of acquired resistance ; therapeutic drug monitoring of novel small molecules and monoclonal antibodies must be incorporated in our day - to - day practice to minimize the negative effect on clinical outcome of interindividual variability on pharmacokinetic processes of these drugs for all patients , but especially for fragile patient populations and those with organ dysfunction or comorbidities . - pubmed
METHODS : From October 2014 to August 2015 , 153 patients with early - stage non - small - cell lung carcinoma ( NSCLC ) and benign disease underwent uniportal subxiphoid VATS major lung resections . - pubmed
RESULTS : Of the 153 patients who underwent surgery with the uniportal subxiphoid VATS approach , 105 had lobectomies and 48 had segmental resections ; 135 cases of lung cancer and 18 cases of benign pulmonary disease were noted . - pubmed
In patients with lung cancer , the mean total number of lymph node stations explored was 3.4 + - 0.8 . - pubmed
Three of these six patients who became re - infected with HBV experienced HCC recurrence after LT . - pubmed
The HBV DNA reappearance rate was significantly higher in patients with HCC recurrence after LT ( p & lt ; 0.001 ) . - pubmed
HCC recurrence and mutations in the HBV S gene were associated with HBV reinfection after LT . - pubmed
CONCLUSIONS : In workers exposed to low levels of MDI and solvents in polyurethane shoe sole production there was a high prevalence of cough and nasal congestion . - pubmed
Nonkeratinizing Squamous Cell Carcinoma In Situ of the Upper Aerodigestive Tract : An HPV - Related Entity . - pubmed
The clinical and pathologic characteristics of human papillomavirus ( HPV)-related premalignant lesions in the upper aerodigestive tract have not been adequately studied . - pubmed
There are a few reports of oral cavity HPV - related severe dysplasia with unique morphology ( prominent apoptosis / karyorrhexis imparting a ' bowenoid ' appearance ) and a single case report of HPV - related squamous cell carcinoma in situ with nonkeratinizing histology distinct from the ' bowenoid ' pattern that extensively involved the upper aerodigestive tract . - pubmed
The aim of this study was to characterize the morphologic and clinical features of HPV - related severe dysplasia / carcinoma in situ . - pubmed
Thus , nonkeratinizing morphology was a strong predictor of transcriptionally - active HPV in severe dysplasia / carcinoma in situ . - pubmed
Moreover , Cu - BGNs showed no significant cytotoxicity towards human mesenchymal stem cells and fibroblast cells at concentrations of 100 , 10 and 1mug / mL. - pubmed
In the present study , an in vitro study model for tumour - induced DC dysfunction was established by culturing DCs with pooled sera from multiple non - small cell lung cancer ( NSCLC ) patients . - pubmed
Head and pelvic movement asymmetries at trot in riding horses in training and perceived as free from lameness by the owner . - pubmed
Recent studies evaluating horses in training and considered free from lameness by their owners have identified a large proportion of horses with motion asymmetries . - pubmed
In a cross - sectional study , vertical head and pelvic movement symmetry was measured in 222 Warmblood type riding horses , all without perceived performance issues and considered free from lameness by their owners . - pubmed
A large proportion ( 72.5 % ) of horses in training which were perceived as free from lameness by their owner showed movement asymmetries above previously reported asymmetry thresholds during straight line trot . - pubmed
We present a series of five patients with appendiceal intussusception and discuss features that may direct the pediatric surgeon to achieve early recognition and provide optimal treatment . - pubmed
MATERIALS AND METHODS : The database of a tertiary medical center was retrospectively reviewed for all patients treated for appendiceal intussusception during the period from January 1995 to January 2016 . - pubmed
Although patients with indolent B - cell lymphomas have a relatively good survival rate , conventional chemotherapy is not curative . - pubmed
Patients affected with urolithiasis , HIV infection , tumors , and vascular and chronic inflammatory bowel diseases were excluded . - pubmed
The inability to propagate human prostate epithelial cells indefinitely has historically presented a serious impediment to prostate cancer research . - pubmed
We have previously reported that prostate CRCs form functional prostate glands when implanted under the mouse renal capsule . - pubmed
CASE DESCRIPTION : A healthy 29 - year - old female presented with intermittent right facial numbness . - pubmed
Effect of the dietary polyacetylenes falcarinol and falcarindiol on the gut microbiota composition in a rat model of colorectal cancer . - pubmed
OBJECTIVES : ( 3R )- Falcarinol ( FaOH ) and ( 3R,8S )- falcarindiol ( FaDOH ) have previously been shown to reduce the number of neoplastic lesions and the growth rate of polyps in the colon of azoxymethane ( AOM ) treated rats . - pubmed
Comparison of the gut microbiota of rats who developed large neoplasms in the colon with rats without large neoplasms showed that the gut microbiota was significantly different in rats who developed large colon neoplasms compared to rats with no macroscopic colon neoplasms . - pubmed
A 38 - year - old woman was suffering from back , right arm , and ankle joint pain , and visited our emergency department . - pubmed
The patient was diagnosed with mixed phenotype lineage acute leukemia , treated immediately , and achieved remission . - pubmed
Background : Cross - facial nerve graft is considered the treatment of choice for facial reanimation in patients with unilateral facial palsy caused by central facial nerve damage . - pubmed
Methods : In this study , cross - facial nerve graft with the sural nerve was planned for three patients with facial palsy through an intraoral approach . - pubmed
Results : DR3 deficiency was associated with restoration of a homeostatic mucosal immunostat in SAMP mice through the regulation of several pro- and anti - inflammatory genes . - pubmed
The present study compared the efficacy and safety of the HPG - HA dual - polymer formulation vs a sodium hyaluronate ( SH)-containing artificial - tear formulation in patients with DED . - pubmed
BACKGROUND : Hepatitis B ( HBV ) transmission may result from in utero transmission . - pubmed
We aimed to determine the correlation between maternal serum and umbilical cord blood HBV DNA levels in infants delivered by chronic HBV - infected mothers and to describe the effect of cord blood viremia on vertical transmission . - pubmed
HBeAg + ve mothers were younger with higher HBV and cord viremia . - pubmed
Infants delivered by HBeAg positive mothers and mothers with high HBV DNA of more than 6 LOG IU / mL ( 1 x 106 IU / mL ) have increased relative risk of cord blood viremia . - pubmed
Several compounds showed promising activity against TBEV ( EC50 0.35 - 0.91 muM ) , but the activity was accompanied by pronounced cytotoxicity . - pubmed
The Effect of Combined Patching and Citalopram on Visual Acuity in Adults with Amblyopia : A Randomized , Crossover , Placebo - Controlled Trial . - pubmed
Nonhuman animal models have demonstrated that selective serotonin reuptake inhibitors ( SSRIs ) can enhance plasticity within the mature visual cortex and enable recovery from amblyopia . - pubmed
Remodeling of the Caenorhabditis elegans non - coding RNA transcriptome by heat shock . - pubmed
While the transcriptional response of PCGs to HS has been comprehensively analyzed in a variety of organisms , the effect of this stress on the expression of non - coding RNAs ( ncRNAs ) has not been systematically examined . - pubmed
Autologous stem cell transplant ( ASCT ) is the standard of care for patients with multiple myeloma ( MM ) . - pubmed
Here we evaluated T cell transcriptional messenger RNA profiles and immunophenotypes to correlate immunologic senescence , exhaustion , and anergy with clinical endpoints in a cohort of patients with MM undergoing ASCT . - pubmed
In this report , we announce the first whole - genome sequencing of six strains of Salmonella enterica isolated from imported meat in Algeria . - pubmed
Incidence and risk factors for major infections in hospitalized children with nephrotic syndrome . - pubmed
INTRODUCTION : Children with nephrotic syndrome are at increased risk of infections because of disease status itself and use of various immunosuppressive agents . - pubmed
This study aimed to determine the incidence , spectrum , and risk factors for major infections in hospitalized children with nephrotic syndrome . - pubmed
METHODS : All consecutive hospitalized children between 1 - 12 years of age with nephrotic syndrome were enrolled in the study . - pubmed
Children with acute nephritis , secondary nephrotic syndrome as well as those admitted for diagnostic renal biopsy and intravenous cyclophosphamide or rituximab infusion were excluded . - pubmed
Incidence of major infections in hospitalized children with nephrotic syndrome was 43.8 % . - pubmed
Streptococcus pneumoniae ( n = 9 ) was the predominant organism isolated in children with peritonitis and pneumonia . - pubmed
As Pneumococcus was the most prevalent cause of infection in those children , attention should be paid to the pneumococcal immunization in children with nephrotic syndrome . - pubmed
A 43 - year - old man with a history of pedestrian - truck collision 18 months prior presented with right - sided abdominal pain and chills . - pubmed
A 50 year - old woman presented with hypoxemia and echocardiographic findings consistent with pulmonary hypertension and cor pulmonale . - pubmed
PTTM is a rare entity that must be considered in cancer patients with unexplained hypoxemia , pulmonary hypertension and lung opacities on imaging . - pubmed
Although structural variations in this organization are an important source of natural genetic diversity , cytogenetic aberrations can also underlie a number of human diseases and disorders . - pubmed
Volume overload is the most common complication in end - stage renal disease ( ESRD ) patients , being directly related to numerous complications including resistant hypertension , cardiac hypertrophy , congestive heart failure or arterial stiffness , among others . - pubmed
: We studied three boys with primary adrenal failure and hypogonadotropic hypogonadism presenting at different ages at the Paediatric Endocrinology Clinic . - pubmed
MATERIALS AND METHODS : We retrospectively reviewed medical records of patients with suspected HL at Kitasato University Hospital in 2017 and 2018 . - pubmed
Case Report : We presented a 3 year - old boy having recurrent seizures since 2 years old and diagnosed as epilepsy and treated with multiple antiepileptic drugs . - pubmed
The patient was hypotonic and neurodevelopmentally poor . - pubmed
The patient was stable on an oral maintenance dose of magnesium oxide with borderline blood magnesium levels without hypocalcemia . - pubmed
The co - existing fatty liver may affect the efficacy of anti - HBV therapy and increase the all - cause mortality rates in patients . - pubmed
The impact of immune - inflammation - nutritional parameters on the prognosis of non - small cell lung cancer patients treated with atezolizumab . - pubmed
METHODS : Twenty - five patients with depression were randomised to either ketamine ( 0.5 mg / kg ) or midazolam ( 0.045 mg / kg ) infusions over 40 min . - pubmed
Patients reported preoperative unilateral low - back pain and weakness when flexing the hip . - pubmed
Since the light / dark assay has historically been used to investigate anxiety - like responses in animals , we measured anxiety in a light - independent open field assay and asked if stimulation of a brain region , the periaqueductal gray , that induces anxiety would yield similar results to posterior thalamic stimulation . - pubmed
Benefits and Harms of Long - term Opioid Dose Reduction or Discontinuation in Patients with Chronic Pain : a Rapid Review . - pubmed
A 61 - year - old woman with a history of primary aldosteronism caused by unilateral hyperplasia of the adrenal gland presented with a 2 - week history of redness and severe pain in the right thumb and thenar regions . - pubmed
Hence , we diagnosed the patient with erythromelalgia caused by polycythemia vera . - pubmed
MATERIALS AND METHODS : 15 healthy controls and 33 patients with long duration ( > = 20 years ) type 1 Diabetes Mellitus ( T1DM ) were recruited . - pubmed
Diabetic subjects were classified into two groups : T1DM , constituted by 14 non - retinopathic patients , and T1DM+RD , constituted by 19 patients in any stage of diabetic retinopathy . - pubmed
Erythrocyte plasmatic membranes of RD patients were found to be more fluid ( GP : 0.43 + -0.03 ) than non - RD patients ( GP : 0.40 + -0.04 ) with a statistically significant difference ( p = 0.035 ) . - pubmed
Effect of Toremifene on Endometrium and Neurocognitive Function in Patients with Breast Cancer Based on Resting State Functional MRI . - pubmed
Methods : A total of 100 patients who received endocrine therapy after breast cancer surgery in our hospital from January 2016 to January 2019 were collected as the research objects . - pubmed
EVs are released into the extracellular space , in most human biological fluids and tissues , including atherosclerotic plaques . - pubmed
Time to initial SCC was analyzed using the Kaplan - Meier method , and Cox proportional hazards regression was used to identify predictors of SCC.Among 384 patients enrolled with MDR - TB , 359 ( 93.5 % ) successfully achieved initial SCC after a median of 85 days ( interquartile range , 40 - 112 days ) . - pubmed
From 4464 screened participants , 557 amyloid - positive , cognitively normal ( Clinical Dementia Rating of 0 ; aged 60 - 85 years ) participants ( approximately 34 % of originally planned 1650 ) were randomized before the trial sponsor stopped enrollment . - pubmed
Our results also highlight the value of using the RCS rat to model sectorial retinitis pigmentosa , a disease known to predominantly effect the inferior retina . - pubmed
OBJECTIVE : To assess the role of TE in HIV infected patients with NAFLD . - pubmed
EXCLUSION CRITERIA : pregnancy ; alcohol intake > = 20g / day and co - infection with hepatitis B or C. Patients underwent abdominal US to diagnose liver steatosis . - pubmed
Liver steatosis was diagnosed in 31 patients ( 31.6 % ) and was independently associated with male sex ( PR= 2.18 ) and higher BMI ( PR=1.08 ) . - pubmed
Among the 31 patients with NAFLD , 26 had results for TE , APRI and FIB4 . - pubmed
CONCLUSIONS : NAFLD prevalence in HIV infected patients is higher than general population . - pubmed
TE > = 7.1kPa was not able to diagnose significant fibrosis , but accurately detect a subgroup of patients with high risk for NASH among HIV monoinfected individuals with steatosis . - pubmed
T cells and human autoimmune thyroid disease : emerging data show lack of need to invoke suppressor T cell problems . - pubmed
In animal models , T cells are able to transfer autoimmune thyroiditis and T cells have , therefore , long been implicated in the etiology of human autoimmune thyroid disease ( AITD ) . - pubmed
Information gained from the study of intrathyroidal T cells and thyroid antigen - specific T - cell clones has shown that in patients with Graves ' disease , mainly helper T - cell clones have been obtained , whereas in autoimmune ( Hashimoto ' s ) thyroiditis cytolytic T - cell clones may be predominant . - pubmed
Recent findings of restricted T - cell receptor V gene use amongst intrathyroidal T cells confirm the primary role of T cells in human thyroid autoimmune processes leading to AITD . - pubmed
When plated at appropriate densities in serum - free media , the COMMA - D mammary epithelial cell line rapidly reorganizes into multicellular spheres on the basement membrane matrix derived from Engelbreth - Holm - Swarm murine tumor . - pubmed
Epithelial respiratory cells from cystic fibrosis patients do not possess specific Pseudomonas aeruginosa - adhesive properties . - pubmed
Nasal polyp cells in primary culture from cystic fibrosis ( CF ) and non - CF patients were compared for the ability to bind Pseudomonas aeruginosa cells and for the presence of sulphated glycoconjugates at the epithelial cell surface . - pubmed
Quantitation of bacterial adhesion , by scanning electronmicroscopy , showed no significant difference between the cells cultured from CF and non - CF patients . - pubmed
The interaction of aggregated P aeruginosa cells with polyp cells cultured from both CF and non - CF patients appeared to occur by means of this matrix material . - pubmed
Our findings suggest that chronic colonisation of the airways of CF patients can not be explained by an increased affinity between the P. - pubmed
inoculated P388 leukemia- and M5076 sarcoma - bearing mice . - pubmed
Furthermore , KW-2149 remarkably increased the life span of MMC - resistant P388 leukemia- and L1210 leukemia - bearing mice . - pubmed
KW-2149 and MMC inhibited the growth of human tumors inoculated into nude mice . - pubmed
The in vitro anticellular spectrum of KW-2149 against 23 human tumor cell lines was similar to that of MMC . - pubmed
The patient was complaining from pains , two years after the first operation in relation to lateral recurrence . - pubmed
Splenic macrophages from tumor - bearing , but not normal , mice were responsible for this immunosuppression , as revealed by negative and positive selection experiments . - pubmed
The levels of lipocortin I mRNA expression were markedly increased in peripheral blood cells from tumor - bearing mice as compared with those from normal mice . - pubmed
Lipocortin I mRNA was strongly induced in splenic mononuclear cells from tumor - bearing mice . - pubmed
Some nonimmune organs such as the heart , submaxillary gland , muscle , and bladder also displayed increased levels of lipocortin I mRNA expression in tumor - bearing mice . - pubmed
Giardia - spontaneously cured mice were rendered resistant to challenge infection . - pubmed
Immune - depressed mice were more susceptible to Giardia infection , thus proving the active role of antibodies and cell - mediated immune response in giardiasis . - pubmed
The long - term results of four different regimens of prednisone therapy were compared in 32 children with steroid sensitive , frequently relapsing idiopathic nephrotic syndrome with minimal glomerular lesions on renal biopsy . - pubmed
In frequently relapsing patients without steroid dependency the relapse free intervals were similar with either intermittent or alternate - day prednisone therapy ( median 75d ) ; however , they were significantly shorter with short - term prednisone therapy ( median 33d ) . - pubmed
This study reports on the frequency of point mutations at these codons , in vivo , in human myeloid malignancies and in normal subjects . - pubmed
Impaired natural defence of beige ( Chediak - Higashi syndrome ) mice against tissue - migrating larvae of Strongyloides ratti and its reconstitution by bone marrow cells . - pubmed
The susceptibility of C57BL/6 - bgJ / bgJ mice , which exhibit a murine counterpart of the Chediak - Higashi syndrome , to infection with Strongyloides ratti was examined . - pubmed
After a primary infection , the peak of the daily larval output in faeces ( LPG ) of bgJ / bgJ mice was approximately twice as high as that of their littermate bgJ/+mice . - pubmed
The total number of tissue migrating larvae recovered from bgJ / bgJ mice at 36 h after infection was also approximately twice as high as that from bgJ/+mice . - pubmed
However , after a primary infection , bgJ / bgJ mice could completely expel adult worms in the intestine by day 14 . - pubmed
The higher susceptibility of bgJ / bgJ mice could be reduced to the level of bgJ/+mice by bone marrow grafting from bgJ/+mice 6 weeks prior to infection . - pubmed
The severity of valvular aortic stenosis was assessed by Doppler color flow mapping in 100 consecutive patients who underwent successful cardiac catheterization within 2 weeks of the Doppler study . - pubmed
The aortic stenosis jet was not seen in 39 patients ( Group B ) , and the mean pressure gradient and aortic valve area in these patients were assessed by conventional Doppler echocardiography alone . - pubmed
The maximal aortic stenosis jet width also correlated well with the aortic valve area estimated at catheterization in 54 patients ( r = 0.90 ) . - pubmed
Effects of antihypertensive treatment on the cerebral microvasculature of spontaneously hypertensive rats . - pubmed
Experiments were performed in anesthetized 18 - 19 - week - old spontaneously hypertensive rats ( SHR ) to evaluate the effects of delayed antihypertensive treatment on cerebrovascular function . - pubmed
Animals were treated for 25 + /- 1 days with an oral antihypertensive regimen consisting of hydralazine , reserpine , and chlorothiazide , resulting in normotension within 2 weeks . - pubmed
Specimens from aganglionic ( constricted ) and ganglionic ( dilated ) gut were obtained from nine patients with Hirschsprung ' s disease . - pubmed
Ten normal subjects and 9 patients affected by aortic regurgitation were used as controls . - pubmed
In eighty consecutive patients who have the dysplastic nevus syndrome , the concentration of nevocytic nevi on the relatively sun - protected lateral thoracic area was compared to the concentration on the relatively sun - exposed areas of the anterior and posterior thorax . - pubmed
These findings are consonant with the hypothesis that sunlight induces nevocytic nevi in patients who have the dysplastic nevus syndrome . - pubmed
The endolymphatic sacs are described in temporal bone specimens from a 31 - year - old man with bilateral Mondini disorder . - pubmed
A severe spinal deformity in a cape buffalo calf ( Syncerus caffer ) similar to " short spine lethal " of Angus cattle ( Bos taurus ) . - pubmed
[ Therapy of liver diseases with protoporphyrin sodium in children ] . - pubmed
Cortical biopsies obtained from 5 young children with severe neurobehavioral retardation of unknown etiology have been analyzed using Golgi and EM techniques . - pubmed
These mice were also capable of rejecting allogeneic mouse skin and rat skin from a strain ( Buffalo ) unrelated to the thymus donor ; however , they were incapable of rejecting rat skin from the thymus donor strain . - pubmed
Experimental auto - allergic sialoadenitis in male rats . - pubmed
Induced auto - allergic lesions in the submandibular glands of rats were studied by immunofluorescence . - pubmed
In individual rats , no relationship was found between the presence or absence of serum anti - salivary antibodies and the presence or absence of salivary auto - allergic lesions . - pubmed
Egg output of Graphidium strigosum ( Nematoda ) in low - level prime infection of rabbits . - pubmed
These derivatives had also an improved antimycoplasmal activity ; MIC values were 0.08 microgram / ml against macrolide - resistant strains of Mycoplasma gallisepticum . - pubmed
As an example of the chemical work done in this study , the analysis of two plants is reported : Pueraria lobata ( Ge - gen ) , which contains an isoflavonoid glycoside with hypotensive effects , with excellent clinical results in the treatment of hypertension ; and Anisodus tanguticus , which contains anisodamine , or 6 - hydroxy hyoscyamine , which proved to be similar in effect to atropine but milder in action on the CNS . - pubmed
Left ventricular thrombi in children with dilated cardiomyopathy . - pubmed
To define the nature and course of left ventricular ( LV ) thrombi in pediatric patients , the charts and echocardiographic records of 32 pediatric patients with dilated cardiomyopathy from 1986 to 1991 were retrospectively reviewed . - pubmed
Five patients who were identified according to echocardiographic evidence of LV thrombi fulfilled the criteria of dilated cardiomyopathy . - pubmed
Systemic embolization occurred in three patients with LV thrombi who invariably died despite anticoagulant treatment . - pubmed
Although it was not statistically significant , patients with LV thrombi tended to have a lower ejection fraction compared to patients without LV thrombi . - pubmed
The morphology of LV thrombi in patients with systemic embolization showed nonprotruding features . - pubmed
Thus , children with dilated cardiomyopathy are at risk of developing LV thrombi and systemic embolization . - pubmed
Although it was not possible to identify the risk factors , the risk of developing LV thrombi and systemic embolization may be higher in patients with lower ejection fraction of the left ventricle . - pubmed
Thrombolytic therapy was administered to a 64 - year - old man with an acute anterolateral myocardial infarction who had received cardiopulmonary resuscitation ( CPR ) for 24 minutes . - pubmed
At the time of thrombolytic therapy , the patient was alert and without clinical or radiographic evidence of injury . - pubmed
The patient developed a retroperitoneal hematoma related to femoral line placement , as well as subcutaneous bruising of the anterior chest wall ; both were self - limited . - pubmed
The use of thrombolytic therapy for patients with acute myocardial infarction who have received CPR is reviewed . - pubmed
In the absence of clinical or radiographic evidence of trauma from CPR , patients with acute myocardial infarction should not be excluded from receiving thrombolytic therapy solely because of having had CPR or the duration of CPR . - pubmed
Scid mice heterotopically transplanted with gut from a congenic , immunocompetent donor developed clinical and histological signs of inflammatory bowel disease ( IBD ) . - pubmed
Changed blood rheology in patients with idiopathic dilated cardiomyopathy . - pubmed
Rheologic properties of blood were studied in 8 patients with dilated cardiomyopathy ( DCM ) and in 10 healthy subjects . - pubmed
The measured hemorheologic abnormalities may contribute to the previously reported reduction of coronary blood flow reserve in DCM patients and to myocardial microcirculatory disturbances , which have been suggested as a cause for DCM . - pubmed
Fine needle aspiration ( FNA ) cytology of lipid - secreting carcinoma of the breast was performed on a 43 - year - old woman who was admitted with a left breast tumor . - pubmed
Pathogenesis of tuberculosis : interaction of Mycobacterium tuberculosis with macrophages . - pubmed
Thoria - labelled murine and human macrophages were infected with a virulent ( H37Rv ) or avirulent ( H37Ra ) strain of M. - pubmed
Only viable H37Rv showed a significant increase in bacterial counts during the course of infection . - pubmed
Thus , both of the attenuated strains we examined differed from the virulent strain H37Rv in their abilities to replicate successfully within macrophages , but each diverged from H37Rv at a different point in the process . - pubmed
Viable tubercle bacilli H37Rv and H37Ra had the capacity to escape from fused vesicles as the infection progressed ; BCG did not . - pubmed
Samples from sixty - two periodontal pockets were collected at pocket depths of over 4 mm in twenty - one periodontitis patients aged 43 to 75 years . - pubmed
However , clinical strains of P. - pubmed
Of all the 487 patients 32 % received thrombolytic treatment ; i.e 36 % of those with definite or suspected myocardial infarction on admission . - pubmed
A 59 - year - old man with mouth pain . - pubmed
MATERIALS AND METHODS : Fourteen breast cancers were examined in 13 women with MRI , ultrasonography and mammography . - pubmed
DNA sequences that cross - hybridize with K139 phage DNA are present in all strains of V. - pubmed
This results suggests that O139 strains arose in part by horizontal gene transfer of the O139 antigen genes into an El Tor O1 strain that harboured a K139 prophage . - pubmed
BACKGROUND AND PURPOSE : Hematoma volume is an important determinant of outcome and predictor of clinical deterioration in patients with intracerebral hemorrhage . - pubmed
METHODS : TCD was performed an average of 1.1 days ( range , 0 to 3 days ) after onset in 30 patients with supratentorial intracerebral hemorrhage . - pubmed
Compared with patients with small hemorrhages , those with large hemorrhages ( & gt ; or = 25 mL , n = 10 ) had significantly higher ipsilateral pulsatility indexes ( 1.72 versus 1.13 , P & lt ; .0001 ) and higher ratios of ipsilateral - to - contralateral pulsatility ( 1.29 versus 1.06 , P = .001 ) . - pubmed
The ratio of ipsilateral - to - contralateral mean velocity was similarly reduced in patients with large versus small hemorrhages ( 0.87 versus 1.06 , P = .01 ) , but this effect was less pronounced . - pubmed
In a prospective , randomised , controlled trial of 92 patients with full - thickness pressure ulcers , the efficacy of an alginate wound dressing was compared to that of an established local treatment with dextranomer paste . - pubmed
During treatment , a minimal 40 % reduction in wound area was obtained in 74 % of the patients in the alginate group and in 42 % of those in the dextranomer group . - pubmed
On this evidence , an attempt is made to interpret earlier discovered changes in the immunobiochemical status of these patients and plausible mechanisms of progressive arterial hypertension are hypothesized . - pubmed
Patients with intracranial aneurysm either present catastrophically with rupture of the aneurysm have aneurysms that are incidentally discovered . - pubmed
On the other hand , the surgical or endovascular mortality following treatment of an unruptured aneurysm is minimal , with good patient neurological outcome . - pubmed
We performed LC on an emergency basis as soon as the diagnosis was made on all patients presenting with acute cholecystitis from January 1994 to December 1995 . - pubmed
Patients with an operative delay of 96 hours or less from the onset of acute cholecystitis had a conversion rate of 23 % , whereas a delay of more than 96 hours was associated with a conversion rate of 47 % ( p = 0.022 ) . - pubmed
Patients over 65 years of age , with a history of biliary disease , a nonpalpable gallbladder , WBC count over 13,000 / cc , and acute gangrenous cholecystitis were independently associated with a high LC conversion rate ; male patients , finding large bile stones , serum bilirubin over 0.8 mg / dl , and WBC count over 13,000 / cc were independently associated with a high complication rate following laparoscopic surgery with or without conversion . - pubmed
Assessment of pretransplantation warm ischemia time by phosphorus-31 magnetic resonance spectroscopy in pig kidneys . - pubmed
Before the onset of colitis , 15 horses had received antibiotics , 11 had undergone general anaesthesia and various surgical procedures , and 10 had been treated with non - steroidal anti - inflammatory drugs . - pubmed
The horses had acute onset , profuse watery diarrhoea , profound depression , mild to moderate abdominal pain , reduced intestinal borborygmi , tachycardia , dehydration and endotoxic shock . - pubmed
The aetiology of the colitis could not be determined , but the clinicopathological features resembled those of colitis attributed to an intestinal overgrowth of Clostridium perfringens type A. - pubmed
PURPOSE : The development of objective criteria for selecting patients for seminal vesicle irradiation on radical radiotherapy for prostate cancer will be important for successful planning of 3D conformal radiotherapy . - pubmed
CONCLUSION : Prospective use of the objective criteria will be useful in the selection of patients for seminal vesicle involvement and should be an integral part in 3D conformal radiotherapy of prostate cancer . - pubmed
We studied the relationship between genetic hypertension and insulin resistance in SHRSP and Wistar Kyoto rats ( WKY ) as a control . - pubmed
We report a case of pseudomembranous necrotizing bronchial aspergillosis in a patient with acute myelocytic leukaemia who died of massive haemoptysis . - pubmed
A 47 year old man with chronic hepatitis C was treated with interferon alfa , 3 million units three times a week , and developed widespread plaque psoriasis within weeks of starting interferon therapy . - pubmed
OBJECTIVE : To investigate the occurrence of combined central and peripheral demyelination in CIDP patients and to correlate visual evoked potential ( VEP ) abnormalities with CNS demyelinating lesions , observed on brain magnetic resonance imaging , and antibodies against glycolipids . - pubmed
METHODS : Nerve conduction studies , brain MRI and antibodies against glycolipids were prospectively studied in 17 patients who fulfilled the diagnostic criteria proposed for CIDP ( Cornblath DR , Asbury AK , Albers JW , Feasby TE , Hahn AF , McLeod JG , Mendell JR , Parry GJ , Pollard JD , Thomas PK . - pubmed
CONCLUSION : This study confirmed the high frequency of abnormal VEPs in CIDP patients , and found that they are poorly correlated with CNS demyelinating lesions and antibodies against glycolipids . - pubmed
The VEP abnormalities of these patients may be explained by the susceptibility to immune - mediated damage of both the peripheral nervous system and the optic nerve . - pubmed
To evaluate the presence of autonomic neuropathy in childhood uremia , cardiovascular autonomic reflexes were examined in children with chronic renal failure . - pubmed
Cardiovascular autonomic reflexes of 10 uremic patients on chronic dialysis and 10 transplanted patients were compared to assess the effect of transplantation on autonomic neuropathy . - pubmed
Of the 10 uremic children , 4 showed early involvement and 2 had definite involvement of autonomic neuropathy . - pubmed
Only 1 of the 10 transplanted patients showed early signs of autonomic neuropathy . - pubmed
In conclusion , cardiovascular autonomic neuropathy is not rare in children and adolescents and young adults with chronic renal failure . - pubmed
In contrast , the prevalence is very low in transplanted patients with similar uremic precedents . - pubmed
Antioxidant and free radical scavenging effects of the tannins of Terminalia catappa L. Reactive oxygen species ( ROS ) react with biological molecules and destroy the structure of cells and eventually cause free radical - induced disease such as inflammation and cancer . - pubmed
ABT-770 and other MMPIs , plus several metabolites of each , were assayed for their ability to induce phospholipidosis in primary cultured rat and human hepatocytes . - pubmed
At 24 and 48 hr , none of the parent compounds induced phospholipidosis in vitro in rat or human hepatocytes . - pubmed
The amine metabolite of another MMPI , ABT-518 ( [ S -( R * , R *)]- N -[ 1 -( 2,2 - dimethyl-1,3 - dioxol-4 - yl )- 2 -[[ 4 -[ 4 -( trifluoromethoxy )- phenoxy ] phenyl ] sulfonyl ] ethyl ]- N - hydroxyformamide ) , produced little phospholipidosis in rat and human hepatocytes even at concentrations up to 100 microM. - pubmed
The presence or absence of phospholipidosis in the in vitro assay correlated well with ultrastructural findings and drug accumulation in rat tissues . - pubmed
Urinary tract infections and a multidrug - resistant Escherichia coli clonal group . - pubmed
Efficacy and tolerance of a scalp - cooling system for prevention of hair loss and the experience of breast cancer patients treated by adjuvant chemotherapy . - pubmed
Women accepting the scalp - cooling system were compared for alopecia both against those who refused and against a " reference " group of 109 patients similarly treated but without being offered a scalp - cooling system . - pubmed
Hair loss in the 105 study patients was evaluated by nurses using World Health Organization ( WHO ) criteria at each cycle of chemotherapy . - pubmed
Tolerance was generally good and no scalp metastasis was observed among the 77 accepting patients followed up . - pubmed
Folate deficiency sensitizes mice to dopaminergic neurodegeneration and motor dysfunction caused by the neurotoxin 1 - methyl-4 - phenyl-1,2,3,6 - tetrahydropyridine ( MPTP ) . - pubmed
A 52 year old man developed a supranuclear gaze palsy and opsoclonus after Diazinon poisoning . - pubmed
[ Contribution of electroencephalography to the study of unilateral cerebral atrophy of children ; correlations of pneumoencephalography and electroencephalography ] . - pubmed
Striatal DAT uptakes were measured in 12 drug - nai;ve schizophrenic patients and 12 age- and sex - matched healthy volunteers . - pubmed
The decreased right uptake and increased left uptake in the striatum might lead to the lack of right - left asymmetry in neuroleptic - nai;ve schizophrenia patients , confirming that the disorder could be due to a disruption in brain lateralization . - pubmed
This is the first report on the use TRODAT to evaluate the DAT density in schizophrenia patients and shows lack of asymmetry in striatal uptake of TRODAT in schizophrenics . - pubmed
The findings also suggest that TRODAT SPECT may be a useful technique to measure dopamine transmission in the human brain and for understanding the pathophysiology of neuropsychiatric disorders . - pubmed
Contrary to our expectations , we found that most patients presented with either an early onset neuropathy with signs and symptoms prior to the onset of walking or a late onset neuropathy with signs and symptoms at around age 40 years . - pubmed
Human gnathostomiasis : clinical study and report of a case . - pubmed
Using a strain of Staphylococcus aureus ATCC 6538P as the test organism , enrofloxacin at concentrations ranging from 3.2 to 12.8 microg ml(-1 ) could be measured in injection . - pubmed
Whilst disorders of short , medium and very long chain acyl dehydrogenases are known , there is no known disorder of LCAD deficiency in humans . - pubmed
Experimental LCAD deficiency in mice shows an acyl - carnitine profile with prominent elevations of unsaturated fatty acid metabolites C14:1 and C14:2 [ Hum . - pubmed
A child with autism whose acyl - carnitine profile also shows these abnormalities is presented , and it is hypothesized that the child may have LCAD deficiency . - pubmed
METHODS : Forty - one anesthetized male mice were subject to thoracic aortic occlusion ( 11 minutes ) through a cervical mediastinotomy followed by 48 hours of reperfusion ( TAR ) under normothermic conditions . - pubmed
PJ34 - treated mice ( PJ , n = 12 ) were given 10 mg / kg PJ34 intraperitoneally 1 hour before ischemia and 1 hour after unclamping . - pubmed
Blinded observers rated murine neurologic status after TAR by using an established rodent paralysis scoring system . - pubmed
RESULTS : Immediately after TAR , UN and PJ mice had severe neurologic dysfunction ( PS = 5.8 + /- 0.1 and 4.6 + /- 0.6 , respectively ; P & gt ; .05 ) , which was significantly worse than the KO mice ( PS = 1.0 + /- 0.7 , P & lt ; .001 ) . - pubmed
After 6 , 24 , and 48 hours KO mice had no discernable neurologic injury ( PS = 0 ) . - pubmed
UN mice did not improve their PS , and Sham mice showed no neurologic abnormality at any time during these experiments . - pubmed
MOTIVATION : Although the outbreak of the severe acute respiratory syndrome ( SARS ) is currently over , it is expected that it will return to attack human beings . - pubmed
This excess risk can be attributed to high rates of chronic hepatitis B viral ( HBV ) infection and low rates of HBV vaccination among Asian immigrants . - pubmed
Iron status and clinical outcome in patients with coronary artery disease after coronary stenting . - pubmed
We conducted this study to investigate whether there is an association between body iron status and clinical outcome in patients with coronary artery disease after coronary stenting . - pubmed
METHODS AND RESULTS : The study included 664 patients with coronary artery disease who underwent coronary stent implantation . - pubmed
CONCLUSIONS : Our study showed no association between iron status and the incidence of major adverse cardiac events or angiographic coronary restenosis in patients with coronary artery disease after coronary stenting . - pubmed
Patients with moderate to severe chronic hepatitis and active HBV replication should be managed according to HBeAg status and presence of coinfecting virus(es ) ( HDV , HCV , HIV ) . - pubmed
Malaria infection in HIV - seropositive and HIV - seronegative individuals in Jos - Nigeria . - pubmed
Helicobacter pylori eradication in peptic dyspepsia . - pubmed
In addition , arthroscopy is a useful adjunct during surgical treatment of patients with certain juxta - articular benign bone tumors . - pubmed
The effect of hyaluronic acid and phospholipid based lubricants on friction within a human cartilage damage model . - pubmed
Levels of start - up friction were determined using an osteoarthritis ( OA ) damaged human cartilage model set within a specially designed friction rig . - pubmed
Institution - specific protocols which reflect current guidelines may increase the number of ST - segment elevation myocardial infarction patients who receive timely reperfusion . - pubmed
BACKGROUND : The management of patients who are receiving warfarin therapy and have musculoskeletal problems that require treatment with a nonsteroidal antiinflammatory drug ( NSAID ) is problematic because NSAID use may increase the risk for bleeding . - pubmed
METHODS : We performed a randomized , controlled , crossover trial to assess the effect on INR of celecoxib versus codeine ( control treatment ) in 15 patients who were receiving warfarin therapy and required analgesic treatment for osteoarthritis . - pubmed
UNLABELLED : The first herpes virus to be described was types 1 and 2 , whose denomination is herpes simplex 1 and 2 or HSV-1 and HSV-2 . - pubmed
METHODOLOGY : We evaluated 38 patients with Bell ' s palsy submitted to anamnesis , clinical and ENT examination and saliva sampling for viral DNA detection by PCR technique . - pubmed
CONCLUSION : The end result was that the presence of HSV-1 in the saliva of patients with Bell ' s palsy indicating that the viral reactivation can be the etiology of this disease . - pubmed
A 43 - year - old woman with a history of cocaine abuse presented with decreased mental responsiveness and cyanosis of the extremities several hours after repeated use of " crack " cocaine . - pubmed
One patient died as a direct consequence of the initial SAH . - pubmed
The technique may be considered as an alternative therapeutic option in selected patients with ruptured VBA - DAs unsuitable for internal trapping of the parent artery . - pubmed
OBJECTIVE : To relate morphology of new bone formation to outcome after tibial lengthening performed in patients with achondroplasia . - pubmed
MATERIAL AND METHODS : A retrospective analysis of 60 tibial segments in 30 achondroplasia patients was performed . - pubmed
Nonetheless , some of the adaptations in the animals on these unique islands may have bearing on my hypotheses related to the incidence and pathogenesis of otitis media in humans . - pubmed
Effects of chronic exposure to DDT and TCDD on disease activity in murine systemic lupus erythematosus . - pubmed
This study examined the effects of chronic exposure to xenoestrogens -- o , p '- dichlorodiphenyltrichloroethane ( DDT ) and 2,3,7,8 - tetrachlorodibenzo - p - dioxin ( TCDD ) on disease activity in the New Zealand Black / New Zealand White F1 hybrid ( B / W ) mouse model of SLE . - pubmed
Taken together , DDT exposure appeared to accelerate the development of albuminuria in lupus - prone mice . - pubmed
TCDD was immunosuppressive to murine SLE . - pubmed
Trichophyton rubrum is the most common agent of dermatophytosis , a disease that affects millions of individuals worldwide . - pubmed
Effect of inhomogeneous static magnetic field on dental pain in humans . - pubmed
Herein , we describe the placement of a novel , self - retaining , active - fixation coronary sinus lead -- the Attain StarFix Model 4195 OTW Lead -- in an elderly heart - failure patient , via the femoral approach . - pubmed
Following spinal cord injury ( SCI ) in mammals , there is only limited repair and consequently only moderate recovery . - pubmed
However , the antihyperglycemic effect of the n - butanol fraction was not observed in diabetic rats . - pubmed
AIMS : To evaluate the prevalence and characteristics of different neurological and psychiatric presentations in patients admitted to hospital with systemic lupus erythematosus ( SLE ) . - pubmed
MATERIALS AND METHODS : In this retrospective hospital - based study , we examined the medical records of patients with SLE who were referred to the hospitals affiliated to Shiraz University of Medical Sciences from 1995 to 2005 . - pubmed
RESULTS : Of the 407 study patients , 11.3 % had neuropsychiatric complications . - pubmed
Acid sphingomyelinase deficiency attenuates bleomycin - induced lung inflammation and fibrosis in mice . - pubmed
[ Prevalence of HPV 16 , 18 , 45 and 31 in women with cervical lesions ] . - pubmed
Multiple infections occurred in 15 % of the cases and infections with other HPV types were detected in 14 % of the sample . - pubmed
CONCLUSIONS : HPV 16 and 18 infections do not always occur as a single infection , and may be associated with other HPV types on different occasions . - pubmed
We describe a 64 - year - old man who presented with progressive dysphagia and weight loss . - pubmed
BACKGROUND AND PURPOSE : The aim of the study was to evaluate the influence of visual control on parameters of postural stability among patients with Parkinson disease ( PD ) in comparison with control subjects . - pubmed
MATERIAL AND METHODS : Fifty patients diagnosed with idiopathic PD and 50 control subjects without features of central nervous system injury were selected for the study . - pubmed
CONCLUSIONS : Visual control significantly affects the parameters of postural stability in PD patients . - pubmed
BACKGROUND : Streptococcus pneumoniae , Moraxella catarrhalis , and nontypeable Haemophilus influenzae is associated with otitis media ( OM ) . - pubmed
Development of an effective vaccine against tuberculosis hinges on an improved understanding of the human immune response to Mycobacterium tuberculosis ( Mtb ) . - pubmed
OBJECTIVE : Patients with primary hyperparathyroidism ( pHPT ) are at increased risk of cardiovascular mortality . - pubmed
METHODS : Twenty - four patients with mild pHPT ( age 56 + - 10 years , blood pressure 136/85 mmHg , serum calcium 2.55 - 3.00 mmol / L ) and 48 control subjects individually matched with cases by age , sex and blood pressure underwent aortic ( carotid - femoral ) and upper - limb ( carotid - radial ) pulse wave velocity ( PWV ) determination by applanation tonometry in a case - control study . - pubmed
Subjects with renal disease , diabetes , treated hypertension or overt cardiovascular disease were excluded from the study . - pubmed
Seventeen of the patients with pHPT were re - examined 4 weeks after surgical parathyroidectomy . - pubmed
Anti - diabetic effect of pyroglutamic acid in type 2 diabetic Goto - Kakizaki rats and KK - Ay mice . - pubmed
Evolutionary and protein structural analyses can provide functional insights into genes implicated in human psychiatric diseases . - pubmed
The effects of high custom made shoes on gait characteristics and patient satisfaction in hemiplegic gait . - pubmed
OBJECTIVE : To determine the effects of a temporary high custom made orthopaedic shoe on functional mobility , walking speed , and gait characteristics in hemiplegic stroke patients . - pubmed
PARTICIPANTS : Nineteen stroke patients ( 12 males ; mean age 55 years ( standard deviation ( SD ) 10 years ) ; mean time post onset 3.6 months ( SD 1.4 months ) ) with a spastic paresis of the lower extremity . - pubmed
[ Update on HPV - induced oropharyngeal cancer ] . - pubmed
Moreover , the present protocol is appropriate for the isolation of microglia from autopsy samples irrespective of the neurological state of the brain or specific brain regions and ( with minor modification ) could be even used for the isolation of microglia from human glioma tissue . - pubmed
When patients die after chiropractic or surgical interventions of the cervical spine , pathologists tasked with the autopsy are frequently overwhelmed by the complicated anatomy , laborious dissections , complex operative procedures and surgical hardware , and the necessity to differentiate artifacts from trauma and disease . - pubmed
OBJECTIVE : To describe 2 patients presenting with idiopathic tinnitus concomitant with eye closure . - pubmed
PATIENTS : Two patients presented with intermittent tinnitus synchronous with eye closing or blinking . - pubmed
Neither patient had facial nerve disease or myoclonus . - pubmed
CONCLUSION : These are the rare 2 reported patients presenting with idiopathic muscular tinnitus concomitant with eye closure . - pubmed
We suggest evaluation of compliance change in impedance audiometry to be a key examination in patients with stapedial muscular tinnitus concomitant with eye closure . - pubmed
METHODS : A sample of 479 individuals aged 50 years or above ( average 66 + - 9.1 years ) , followed in primary care , with no history of brain disorder were asked two questions concerning SLC , fulfilled a depression scale and undertook a battery of cognitive tests . - pubmed
Perioperative considerations in patients with Gitelman syndrome : a case series . - pubmed
STUDY OBJECTIVE : To determine the perioperative considerations for low - risk and high - risk surgery in patients with Gitelman syndrome . - pubmed
PATIENTS : 42 patients with Gitelman syndrome . - pubmed
MEASUREMENTS : Of the 42 patients with Gitelman syndrome , 5 underwent procedures requiring anesthesia : mastectomy , spinal fusion , thyroidectomy , tonsillectomy , and bronchoscopy . - pubmed
MAIN RESULTS : No acute electrolyte abnormalities or postoperative complications occurred with these procedures in patients with Gitelman syndrome . - pubmed
Bevacizumab versus ranibizumab in the treatment of exudative age - related macular degeneration : a retrospective study of 58 patients . - pubmed
PATIENTS AND METHODS : Retrospective case - controlled series of 30 patients treated with intravitreal bevacizumab and 28 patients treated with intravitreal ranibizumab for exudative AMD . - pubmed
Total arterial off - pump coronary artery bypass in a patient with situs inversus and dextrocardia . - pubmed
Genetic alterations and deregulation of the miRNA biogenesis pathway components have been reported in human tumors . - pubmed
This study investigated the effects of steady - state liraglutide 1.8 mg versus placebo on postprandial plasma lipid concentrations after 3 weeks of treatment in patients with type 2 diabetes mellitus ( T2DM ) . - pubmed
METHODS : In a cross - over trial , patients with T2DM ( n = 20 , 18 - 75 years , BMI 18.5 - 40 kg / m2 ) were randomized to once - daily subcutaneous liraglutide ( weekly dose escalation from 0.6 to 1.8 mg ) and placebo . - pubmed
Serum copper , zinc and selenium levels in Tunisian patients with Parkinson ' s disease . - pubmed
METHODS : A serum level of 3 trace elements ( Cu , Zn and Se ) was investigated in 48 patients with PD and 36 matched controls using plasma atomic absorption spectrometry . - pubmed
We compared these parameters in PD patients with controls , and we also compared the variations within the PD group according to age , illness duration , stage of the disease and levodopa intake . - pubmed
RESULTS : Patients with PD had significantly lower Cu levels compared to controls . - pubmed
The mean Zn and Se levels in PD patients did not differ significantly from those of controls . - pubmed
Lymph node metastasis in gastric cardiac adenocarcinoma in male patients . - pubmed
METHODS : We retrospective reviewed a total of 146 male and female patients with gastric cardiac adenocarcinoma who had undergone curative gastrectomy with lymphadenectomy in the Department of Surgery , Xin Hua Hospital and Rui Jin Hospital of Shanghai Jiaotong University Medical School between November 2001 and May 2012 . - pubmed
RESULTS : The rate of lymph node metastases in male patients with gastric cardiac adenocarcinoma was 72.1 % . - pubmed
Univariate analysis showed an obvious correlation between lymph node metastases and tumor size , gross appearance , differentiation , pathological tumor depth , and lymphatic invasion in male patients . - pubmed
Multivariate logistic regression analysis revealed that tumor differentiation and pathological tumor depth were the independent risk factors for lymph node metastases in male patients . - pubmed
There was an obvious relationship between lymph node metastases and tumor size , gross appearance , differentiation , pathological tumor depth , lymphatic invasion at pN1 and pN2 , and nerve invasion at pN3 in male patients . - pubmed
There were no significant differences in clinicopathological features or lymph node metastases between female and male patients . - pubmed
CONCLUSION : Tumor differentiation and tumor depth were risk factors for lymph node metastases in male patients with gastric cardiac adenocarcinoma and should be considered when choosing surgery . - pubmed
Quantifying vascular heterogeneity using microbubble disruption - replenishment kinetics in patients with renal cell cancer . - pubmed
PURPOSE : The purposes of this study were to establish the physiological interpretation of the shape parameter of the dynamic contrast - enhanced ultrasound ( DCE - US ) lognormal perfusion model and to evaluate the clinical significance of the parameter in a sample of patients undergoing antiangiogenic therapy for metastatic renal cell carcinoma ( mRCC ) . - pubmed
Dynamic contrast - enhanced ultrasound data were obtained from 31 consenting patients with mRCC being treated with antiangiogenic therapy . - pubmed
A more abnormal flow distribution at baseline predicts for poorer outcome for patients treated with antiangiogenic therapy for metastatic renal cell cancer . - pubmed
METHODS : Patients diagnosed with a pituitary adenoma and treated with two or more courses of radiation treatment ( RT ) to the sella were retrospectively analyzed for : initial diagnosis , including histological type and functional status ; RT modality , technique , dose , and fractionation ; treatment with surgery , endocrine agents , and chemotherapy ; toxicity of RT including radiation - induced optic neuropathy , radionecrosis , and radiation - induced neoplasms ; and outcomes including local control , distant metastasis , biochemical control of functional tumors , and vital status at last follow - up . - pubmed
RESULTS : We identified 15 patients with non - functioning pituitary adenoma ( n = 6 ) , Cushing ' s disease ( CD ) ( n = 5 ) , acromegaly ( n = 3 ) , and prolactinoma ( n = 1 ) . - pubmed
Radiation - induced optic neuropathy ( RION ) was observed in 2 ( 13.3 % ) patients , 6 months and 14 years after re - irradiation ; the 5 - year rate of RION was 9 % . - pubmed
Biochemical remission occurred in one of three patients with CD . - pubmed
Four patients ( 27 % ) ultimately developed pituitary carcinoma . - pubmed
Antioxidant effects of maslinic acid in livers , hearts and kidneys of streptozotocin - induced diabetic rats : effects on kidney function . - pubmed
We , therefore , investigated the effects of 5 - week MA treatment of streptozotocin ( STZ)-induced diabetic rats on anti - oxidative status of cardiac , hepatic and renal tissues as well as on kidney function . - pubmed
In the United Kingdom , European badgers Meles meles are a protected species and an important wildlife reservoir of bovine tuberculosis . - pubmed
Methamphetamine ( Meth ) can evoke extreme hyperthermia , which correlates with neurotoxicity and death in laboratory animals and humans . - pubmed
Modern soya formulas are used in allergy / intolerance to cows ' milk - based formulas ( CMF ) , post - infectious diarrhoea , lactose intolerance and galactosaemia , as a vegan human milk ( HM ) substitute , etc . - pubmed
Feasibility study of personalized peptide vaccination for metastatic recurrent triple - negative breast cancer patients . - pubmed
Herein we conducted a phase II study of PPV for metastatic recurrent breast cancer patients to investigate the feasibility of PPV for mrTNBC . - pubmed
METHODS : Seventy - nine patients with metastatic recurrent breast cancer who had metastases and had failed standard chemotherapy and/or hormonal therapy were enrolled . - pubmed
In this study bipolar RF was assessed in the 20 subjects , who are in treatment of periorbital rhytides and it was proved that it can successfully treat the periorbital rhytides . - pubmed
Cytotoxic activity of the methanolic extract of Turnera diffusa Willd on breast cancer cells . - pubmed
The aim of the present study was to evaluate the possible cytotoxic effect of extracts and organic fractions of this plant on five tumor cell lines ( SiHa , C-33 , Hep G2 , MDA - MB-231 , and T-47D ) and normal human fibroblasts . - pubmed
This is the first report of a cytotoxic effect by T. - pubmed
A preliminary observation of weight loss following left gastric artery embolization in humans . - pubmed
However , weight loss after LGA embolization in humans has not been previously established . - pubmed
The aim of this study was to evaluate postprocedural weight loss in patients following LGA embolization . - pubmed
SUBJECTS / METHODS : A retrospective analysis of the medical records of patients who underwent LGA embolization for upper gastrointestinal ( GI ) bleeding was performed . - pubmed
Postprocedural weight loss in this group was compared to a control group of patients who had undergone embolization of other arteries for upper GI bleeding . - pubmed
CONCLUSIONS : The current data suggest that body weight in humans may be modulated via LGA embolization . - pubmed
A first - in - human clinical trial of ultrasmall inorganic hybrid nanoparticles , " C dots " ( Cornell dots ) , in patients with metastatic melanoma is described for the imaging of cancer . - pubmed
( 124 ) I - cRGDY - PEG - C dot particles are inherently fluorescent , containing the dye , Cy5 , so they may be used as hybrid PET - optical imaging agents for lesion detection , cancer staging , and treatment management in humans . - pubmed
Coupled with preferential uptake and localization of the probe at sites of disease , these first - in - human results suggest safe use of these particles in human cancer diagnostics . - pubmed
Parathyroid carcinoma with intracranial metastasis at diagnosis in a patient with uncontrolled hypercalcemia . - pubmed
We report a case of metastatic parathyroid carcinoma with two intracranial metastatic foci ( in the left frontal lobe and left cerebellar hemisphere ) identified at the time of the primary tumor diagnosis in a patient who presented with symptomatic hypercalcemia . - pubmed
Significant work has been done towards identifying the health - beneficial effects of the grape antioxidant resveratrol in a variety of bioassay- and disease- models , with much research being focused on its possible application to cancer management . - pubmed
Dysphagia , hoarseness , and globus in a postoperative patient . - pubmed
We present a case of a single patient who presented to a tertiary care center after an elective outpatient procedure with postoperative sore throat , hoarseness , and dysphagia . - pubmed
BACKGROUND : Coagulopathy is a major issue in children undergoing high - risk pediatric cardiac surgery . - pubmed
This study aims to study the benefits tranexamic acid in controlling postoperative bleeding in pediatric cardiac surgical patients . - pubmed
Intraperitoneal administration of butyrate prevents the severity of acetic acid colitis in rats . - pubmed
The current study aimed at exploring and comparing the potential of intraperitoneally , intrarectally , and orally administered butyrate against acetic acid ( AA)-induced UC in rats . - pubmed
We herein report a 35 - year - old woman with cardiac diffuse large B - cell lymphoma ( DLBCL ) with breast infiltration . - pubmed
The patient was admitted to our hospital based on an initial presentation with dyspnea on exertion , chest pain , and a hard mass of the left breast . - pubmed
The increase in body weight ( Deltabody weight ) in patients without knee problems was 13.5 kg ( 95 % CI 12.9 - 14.2 , range 3 - 38 ) . - pubmed
Patients with incident knee pain experienced a Deltabody weight of 16.8 kg ( 95 % CI 13.9 - 19.4 , range 6 - 35 ) . - pubmed
The compounds were active against 9 out of 12 tested microorganisms including a resistant strain ; vancomycin - resistant entrococci ( VRE ) , Escherichia coli , Staphylococcus aureus and Candida albicans . - pubmed
MATERIALS AND METHODS : This review delves further into the current literature to discuss a possible algorithm for managing the risk of stress incontinence after pelvic organ prolapse repair and examines the support in the literature for the following treatment methods : ( 1 ) anti - incontinence surgery for all women undergoing pelvic organ prolapse repair , ( 2 ) anti - incontinence surgery for no women undergoing pelvic organ prolapse repair , and ( 3 ) anti - incontinence surgery in select women undergoing pelvic organ prolapse repair . - pubmed
OBJECTIVES : The classical presentation of giant cell arteritis ( GCA ) includes the new onset of headache , scalp tenderness , facial pain or jaw claudication in an older patient . - pubmed
Results after En Bloc Lateral Wall Decompression Surgery with Orbital Fat Resection in 111 Patients with Graves ' Orbitopathy . - pubmed
A retrospective , noncomparative case series study from 1999 to 2011 ( chart review ) in Graves ' orbitopathy ( GO ) patients . - pubmed
Mean exophthalmos reduction was 3.05 mm and preoperative orbital pressure sensation resolved or improved in all patients . - pubmed
Preoperative diplopia improved in 10 patients ( 9.0 % ) but worsened in 5 patients ( 4.5 % ) , necessitating surgical correction in 3 patients . - pubmed
There were no significant complications ; however , one patient had slight hollowing of the temporalis muscle around the scar that did not necessitate revision , and another patient with a circumscribed retraction of the scar itself underwent surgical correction . - pubmed
The study confirms the efficiency of en bloc lateral wall decompression in GO in a large series of patients , highlighting the low risk of disturbance of binocular functions and of cosmetic blemish in the temporal midface region . - pubmed
Pharmacokinetic and Pharmacodynamic Properties of Oral Voriconazole in Patients with Invasive Fungal Infections . - pubmed
PATIENTS : Fifteen hospitalized patients with proven IFIs who were treated with oral voriconazole for at least 2 weeks . - pubmed
fAUC24 : MIC values higher than 25 and fCmin : MIC values higher than 1 may predict clinical response in patients with IFIs . - pubmed
Designing an optimal dosage regimen based on individual PK / PD properties will improve the efficacy in patients with IFIs . - pubmed
The isolates were assessed for their cytotoxicity against five human tumour lines ( HL-60 , SMMC-7721 , A-549 , MCF-7 and SW-480 ) , and the result showed that only 2 displayed weak inhibitory activity . - pubmed
Although cardiac hypertrophy developed similarly in both KO and WT mice after daily isoproterenol ( ISO , 100 mg / kg ) treatment via intraperitoneal injection for 2 weeks , they were functionally indiscernible . - pubmed
In the past decade , the laparoscopic approach in trauma patients has shown better diagnostic outcomes than traditional laparotomies . - pubmed
OBJECTIVE : To evaluate the feasibility , safety , and clinical outcomes of plug - assisted retrograde transvenous obliteration ( PARTO ) to treat gastric variceal hemorrhage in patients with portal hypertension . - pubmed
MATERIALS AND METHODS : From May 2012 to June 2014 , 19 patients ( 11 men and 8 women , median age ; 61 , with history of gastric variceal hemorrhage ; 17 , active bleeding ; 2 ) who underwent PARTO using a vascular plug and a gelfoam pledget were retrospectively analyzed . - pubmed
RESULTS : Technical success ( complete occlusion of the efferent shunt and complete filling of gastric varix [ GV ] with a gelfoam slurry ) was achieved in 18 of 19 ( 94.7 % ) patients . - pubmed
The embolic materials could not reach the GV in 1 patient who had endoscopic glue injection before our procedure . - pubmed