The effect of trigeminal nerve and
ganglion manipulation on
recurrence of
ocular herpes simplex in
rabbits . -
pubmed
Latent
herpes simplex virus (
HSV ) has been demonstrated in the trigeminal ganglia of experimentally infected
rabbits between episodes of spontaneous ocular
recurrence . -
pubmed
These studies provide additional evidence for the theory that the reservoir for latent ocular
HSV in
rabbits is the trigeminal
ganglion . -
pubmed
Moreover , the studies suggest that the transmission of latent
HSV from the trigeminal
ganglion to its infectious form in the peripheral tissues involves the trigeminal nerve . -
pubmed
We have shown that mechanical and stereotaxic stimulation of the trigeminal
ganglion is a reliable and rapid means of precipitating peripheral ocular shedding of
HSV on command , a finding which should prove most productive in future research . -
pubmed
[ Ultrastructural changes in the central nervous system of
monkeys in
poliomyelitis ] . -
pubmed
The ultrastructure of cells of the central nervous system of
Rhesus monkeys in experimental
poliomyelitis caused by virus of
poliomyelitis Type 3 was studied . -
pubmed
Laminitis in the
horse . -
pubmed
To our knowledge , only one experimental study has mentioned morphological lesions similar to the
hemolytic uremic syndrome in the
human . -
pubmed
Hepatitogenicity of three plaque purified mutant
strains of
mouse hepatitis virus , designated as MHV-2S , -2 M and -2L , isolated from
MHV-2 infected
SR - CDF1 - DBT cells was studied . -
pubmed
Immunofluorescence revealed
MHV specific antigen in the liver of MHV-2S infected
mice in and around
necrotic areas though less extensive than that of parental MHV-2 infected
mice . -
pubmed
With
MHV-2 M specific fluorescence was restricted in degenerated hepatocytes in the small
necrotic foci . -
pubmed
In
mice inoculated with MHV-2L only
faint fluorescence was detected . -
pubmed
Histopathologically , in the liver of MHV-2S infected
mice zonal
necrosis and cell infiltration were observed . -
pubmed
There were spotty
necrosis and focal cell infiltration in the liver of MHV-2 M infected
mice and only small inflammatory foci were seen in MHV-2L infected
mice . -
pubmed
Thus , in
rat cardiac myocytes a reduction in the myofilament
Ca2 + response , possibly due to a decrease in myofilament
Ca2 + sensitivity , is a mechanism for contractile
depression due to clinically relevant
ETOH concentrations. -
pubmed
Some health care administrators have discussed the propriety the routine testing of faculty and students for
HIV disease , especially when invasive procedures are involved : This article discusses some of the legal issues which attend routine
HIV testing in this context . -
pubmed
Mixed
infection of the mosquitoes ' larvae of the first age group by densonucleasis virus and entomopathogenic
strains of
Pseudomonas fluorescens and
Serratia marcescens enhanced
viral infection in the presence of
toxicosis induced by exogenic entomotoxic bacterial metabolites . -
pubmed
Sixty - nine
patients , mean age 50.0 years with an
ischaemic cerebrovascular attack in the carotid circulation were subjected since 1983 to a complete examination incl . -
pubmed
Recent studies have suggested that
Plesiomonas shigelloides is a cause of
diarrhea . -
pubmed
shigelloides - infected patients had findings suggestive of
colitis , and
P. - pubmed
Continuous arteriovenous haemodialysis in
critically ill patients . -
pubmed
Continuous arteriovenous haemodialysis ( CAVHD ) is a new treatment for
critically ill patients with
renal failure that combines convective and diffusive solute removal . -
pubmed
The clearance of
urea ( 14.8 - 22.1 ml / min ) is sufficient to achieve a steady - state
urea concentration of 22 mmol / l , even in
patients with a high catabolic rate and
cardiovascular instability . -
pubmed
Initial experience in 36
critically ill patients with
renal failure indicates that it is safe and reliable , with less associated morbidity than other techniques . -
pubmed
Treatment of
cryptococcal meningitis in
mice with
fluconazole . -
pubmed
We compared
fluconazole in
murine cryptococcosis with
ketoconazole and
amphotericin B. -
pubmed
Fluconazole was highly effective in suppressing
cryptococcosis in
mice challenged by the intravenous and intranasal routes , and was comparable with the other two drugs in its protective capacity . -
pubmed
PMNs were collected from the
rat pleural cavity after induction of one acute inflammatory reaction (
pleurisy induced by injection of a suspension of
calcium pyrophosphate crystals ) . -
pubmed
To determine the effect of
lithium carbonate on the productivity and idiosyncrasy of written associations of euthymic
outpatients with
affective disorder , the authors assessed 22
patients at weekly intervals during
lithium treatment , 2 consecutive weeks of placebo , and 2 consecutive weeks after
lithium was resumed . -
pubmed
Reproductive and endocrine gonadal functions in
adults following multidrug chemotherapy for
acute lymphoblastic or undifferentiated leukemia . -
pubmed
The impact of aggressive chemotherapy on reproductive and endocrine gonadal function was studied in ten
women and ten
men with
acute lymphoblastic leukemia (
ALL ) or
acute undifferentiated leukemia (
AUL ) in complete remission . -
pubmed
These results demonstrate that multidrug chemotherapy induced significant
impairment of reproductive function in all male
patients with early and complete recovery . -
pubmed
Since the magnitude of such increases is thought to reflect the degree of
lung injury , the results suggest that
O3 exposure causes greater
lung injury in older
rats than in younger
rats . -
pubmed
The results of these studies further demonstrate that older
rats are more susceptible to
lung injury from
O3 than younger
rats . -
pubmed
The effects of
oxalate treatment on the
smear layer of ground surfaces of
human dentine . -
pubmed
The role of oncogene expression in
tumor metastasis was examined using the
Abelson leukemia virus - transformed
murine large cell lymphoma RAW117 . -
pubmed
Histochemistry of synovium in experimental
haemarthrosis in the
rabbit . -
pubmed
[ Clinical aspects and diagnosis of
congenital dysfunction of the adrenal cortex ( salt - loosing form ) in young
children ] . -
pubmed
Induction of
chromosomal aberrations and mutations with isomeric forms of
L - threitol - I,4 - bismethanesulfonate in
plant materials . -
pubmed
The growth of Ehrlich 's
ascites carcinoma in
C3H mice and in
mice of an unrelated closed colony . -
pubmed
Hemodynamic and metabolic effects of physical training in four
patients with
essential hypertension . -
pubmed
Stage - specific transforming genes of
human and
mouse B- and T - lymphocyte
neoplasms . -
pubmed
DNAs of 20
B - and T - lymphocyte neoplasms of
human and
mouse origin induced transformation of
NIH / 3T3 cells with high efficiencies , indicating that these
neoplasms contained activated transforming genes that were detectable by transfection . -
pubmed
A case is reported of the reconstruction of a continent anus after an abdominoperineal resection for a
patient who presented with a Dukes B
adenocarcinoma at 4.5 cm from the anal verge . -
pubmed
[ Effects of
anisodamine on pulmonary circulation and function of the
dog in
shock ] . -
pubmed
FH rats do not closely resemble
CHS mice or
human beings in having deficient NK activity and can not be considered the
rat homolog of the
CHS . -
pubmed
Breathlessness was measured in 20
patients with severe
chronic obstructive lung disease by the use of a visual - analogue scale . -
pubmed
The value of short - term intermittent
oxygen in
patients with severe
chronic obstructive lung disease needs to be evaluated in terms of both exercise ability and
breathlessness . -
pubmed
A 3.5 - year - old
boy with
eosinophilic cystitis was extensively investigated , but there was no evidence of parasitism . -
pubmed
Pharmacodynamic interaction between
hydralazine and
phenobarbital in normotensive and spontaneously
hypertensive rats . -
pubmed
Primary indications include preoperative assessment of fluid and volume status , evaluation of
patients with severe
heart disease , and management of
multisystem organ failure . -
pubmed
For a neuropathological analysis of degenerative changes in
saccadic disorders of
patients , the histological identification of the burst neuron areas in
man is important . -
pubmed
Kinematic and dynamic axial computed tomography of the patello - femoral joint in
patients with
anterior knee pain . -
pubmed
Thirty - eight knees of 26
patients with
anterior knee pain ( 12 bilateral ) were included in the study . -
pubmed
In 38
IDDM patients , there were four cases with
microalbuminuria and one case with overt
nephropathy . -
pubmed
The measurements of UA in single - void specimens by ELISA is a satisfactory approach to detect impending
nephropathy in
IDDM patients . -
pubmed
We determined the pharmacokinetics of
6 - methoxy-2 - naphythylacetic acid (
6 - MNA ) , the active metabolite of
nabumetone , in normal
subjects and in
subjects with
impaired renal function , including
subjects requiring hemodialysis . -
pubmed
However , the increased half - life in
patients with
renal failure is offset by changes in the apparent volume of distribution that prevent the accumulation of
6 - MNA in the serum of
patients with
impaired renal function . -
pubmed
Therefore dosage adjustments may not be necessary in
patients with
decreased renal function . -
pubmed
A 43 year old
man with inoperable
aortic coarctation and severe
hypertension requiring near maximal anti -
hypertensive treatment was admitted in severe
heart failure . -
pubmed
The
patient was re - admitted a week later with gross fluid retention and in
renal failure . -
pubmed
We propose that the renal haemodynamics in severe
aortic coarctation are similar to those in bilateral severe
renal artery stenosis and advise caution in the use of
ACE inhibitors for
adults with
aortic coarctation . -
pubmed
Strains of
Bacteroides fragilis isolated from clinical specimens are known to be frequently resistant to
penicillins or
cephalosporins . -
pubmed
Antiemetics in
children receiving
cancer chemotherapy . -
pubmed
Side effects were found in 3
patients (
oliguria , 2 ;
eruption due to drug , 1 ) and one case resulted in serious
renal disorder . -
pubmed
Thirty - two percent of hypothalamic neurons were stimulated by a
hypercapnic stimulus in intact
cats ; of those that were stimulated by
hypercapnia , all had a basal discharge related to cardiovascular and/or respiratory activity . -
pubmed
Hypoxia significantly increased the discharge rate of 21 % of hypothalamic units in intact
animals ; 90 % of those had a cardiovascular and/or respiratory - related rhythm . -
pubmed
PURPOSE : This study investigates the response rate to and
toxicity of
carboplatin and
vincristine in
children with recurrent low - grade
gliomas (
LGGs ) or
patients younger than 60 months with newly diagnosed
LGGs . -
pubmed
PATIENTS AND METHODS : Twenty - three
children with recurrent and 37
children with newly diagnosed
LGGs were treated with a 10 - week induction cycle of
carboplatin and
vincristine , followed by maintenance treatment with the same drugs . -
pubmed
RESULTS : Twelve of 23 ( 52 % + /- 10 % ; 95 % confidence interval [ CI ] , 0.32 to 0.72 ) assessable
children with recurrent disease had an objective response to treatment , which included a greater than 50 % reduction in
tumor size in seven of 23 ( 30 % + /- 10 % ; 95 % CI , 0.10 to 0.50 ) . -
pubmed
Twenty - three of 37 ( 62 % + /- .08 ; 95 % CI , 0.46 to 0.78 ) of newly diagnosed
patients had an objective response , 16 of 37 ( 43 % + /- 0.08 % ; 95 % CI , 0.27 to 0.59 ) with greater than 50 % reduction in
tumor size . -
pubmed
The majority of those with an objective response had
diencephalic tumors ( n = 29 ) , but
children with thalamic ( n = 2 ) , cortical ( n = 1 ) , and brain stem ( n = 2 )
LGGs also responded to treatment . -
pubmed
Hematologic
toxicity was common , but resulted in cessation of therapy in only one
patient . -
pubmed
Six
children have been removed from the study because of
allergic reactions , which were considered to be
carboplatin - associated . -
pubmed
CONCLUSION :
Carboplatin and
vincristine have activity in
children with recurrent and newly diagnosed progressive
LGGs . -
pubmed
This drug regimen is relatively well tolerated , and further studies are indicated to define the role of this combination of drugs in
children with newly diagnosed
LGGs . -
pubmed
ONO-1078 antagonizes
diarrhea - causing changes in ion transport and smooth muscle contraction induced by
peptidoleukotrienes in
rat and
human colon in vitro . -
pubmed
BACKGROUND : To diagnose baker 's
asthma , occupational sensitization to
wheat flour should be distinguished clearly from influences of cosensitization such as it may exist in
pollinosis patients . -
pubmed
Use of
amiloride to reduce osmotic stress
injury of
mouse oocytes during cryopreservation . -
pubmed
Our survey confirms that for treating physicians there remain uncertainties regarding the relative efficacy and tolerability of available antidepressant medications for
patients with
PD . -
pubmed
METHODS AND RESULTS : A total of 14 617
women who reported
hypertension and regular use of diuretics , beta - blockers ,
calcium channel blockers ,
ACE inhibitors , or a combination in 1988 were included in the analyses . -
pubmed
Circular RNAs reminiscent of viroids and the
human hepatitis delta virus have been proposed as possible nonconventional pathogens responsible for
Crohn ' s disease and
ulcerative colitis , two
inflammatory bowel diseases . -
pubmed
[ Immediate - acting oral
morphine sulfate in
patients with
cancer pain ] . -
pubmed
In this article , we describe our experience with oral
morphine for the treatment of
patients with
cancer pain who were referred to a Palliative Care Unit . -
pubmed
In 50
patients ( 96 % ) , there was a decreased intensity of
pain from severe ( Visual Analogue Scale average ( VAS ) 8.7 ) to mild ( VAS average 1.9 ) . -
pubmed
Even though most authors recommend
morphine q4h , in our population q6h was enough to achieve
pain control in 83 % of
patients . -
pubmed
It should be known by the medical population that
morphine is essential therapy for
pain in
cancer patients . -
pubmed
This study confirms that
morphine is an excellent drug for the control of
pain in
cancer patients , with minimal dosages and controllable side effects . -
pubmed
We present a case of a radically resected
duodenal stromal tumour with benign features , in a young
woman , with
metastases to the liver and peritoneum occurring 8 years after the initial diagnosis . -
pubmed
BACKGROUND : Induction chemotherapy has become the standard of care for
patients with locally advanced
breast cancer ( LABC ) and currently is being evaluated in prospective clinical trials in
patients with earlier - stage disease . -
pubmed
To better gauge the role of axillary lymph node dissection in
patients with LABC this study was performed to assess initial axillary status on physical and ultrasound examination , axillary
tumor downstaging following induction chemotherapy , and the accuracy of physical examination compared with axillary sonography in predicting which
patients will have axillary lymph node
metastases found on pathologic examination . -
pubmed
METHODS : Between 1992 and 1996 , 147 consecutive
patients with
LABC were registered in a prospective trial of induction chemotherapy using
5 - fluorouracil ,
doxorubicin , and
cyclophosphamide . -
pubmed
RESULTS : Following induction chemotherapy , 43 ( 32 % ) of the 133
patients with clinically positive lymph nodes on initial examination had axillary
tumor downstaging as assessed by physical and ultrasound examination . -
pubmed
Among the 55
patients in whom the findings of both physical and ultrasound examination of the axilla were negative following induction chemotherapy , 29
patients ( 53 % ) were found to have axillary lymph node
metastases on pathologic examination of the axillary contents . -
pubmed
However , 28 ( 97 % ) of these
patients had either 1 to 3 positive lymph nodes or only
micrometastases 2 to 5 mm in diameter . -
pubmed
CONCLUSIONS : Preoperative clinical assessment of the axilla by physical examination combined with ultrasound examination is not completely accurate in predicting
metastases in
patients with LABC following
tumor downstaging . -
pubmed
However ,
patients with negative findings on both physical and ultrasound examinations of the axilla may be potential candidates for omission of axillary dissection if the axilla will be irradiated because minimal
axillary disease remains . -
pubmed
Gold - thioglucose - induced
hypothalamic lesions inhibit metabolic modulation of light - induced circadian phase shifts in
mice . -
pubmed
2 - deoxy - D - glucose and in
hypoglycemic mice fasted for 30 h , pre - treated with 5 IU / kg s.c . -
pubmed
In contrast , similar metabolic challenges in
mice with
gold - thioglucose - induced
hypothalamic lesions did not significantly affect light - induced phase delays compared to
mice treated with
gold - thioglucose and fed ad libitum . -
pubmed
This concept has engaged scientists to investigate
human models to explore the molecular basis of
hypertrophy or dilation of the myocardium . -
pubmed
Helicobacter pylori infection in postoperative
patients with
biliary atresia . -
pubmed
The prevalence of
Helicobacter pylori infection in postoperative
patients with
biliary atresia (
BA ) was investigated in relation to
esophageal varices ,
portal - hypertensive gastropathy (
PHG ) , and
peptic ulcer disease (
PUD ) in 25 Japanese patients ( 10
boys and 15
girls ) aged from 16 months to 20 years . -
pubmed
Esophageal varices were found in 19
patients ( 60 % of group A and all
patients in groups B and C ) and PHG in 3 group B patients . -
pubmed
pylori infection and
PUD in postoperative
patients with
BA was quite low , and a pathological relationship with the severity of
liver disease could not be determined in these patients . -
pubmed
The Centers for Disease Control and Prevention
HIV classifications for the 18
HIV - infected children were : A ( n = 7 ) , B ( n = 6 ) , and C ( n = 5 ) . -
pubmed
By parent report , 7
HIV - infected children napped and 2 noninfected children napped , indicating greater
daytime fatigue in the HIV - infected children . -
pubmed
HIV - infected children also reported a greater level of evening
tiredness ( 2.47 vs 1.8 ) . -
pubmed
Some new approaches are described for
patients with
hormone - refractory prostate cancer . -
pubmed
CONCLUSIONS : Newer
tumor - biology - based combinations are promising in the treatment of
hormone - refractory prostate cancer , but their effect on
patient survival needs to be evaluated in larger clinical trials . -
pubmed
Seasonal consumption of
salad vegetables and fresh fruit in relation to the development of
cardiovascular disease and
cancer . -
pubmed
OBJECTIVE : To investigate the protective association between seasonality of consumption of fresh fruit or
salad vegetables and
cancer and
cardiovascular disease (
CVD ) development . -
pubmed
CONCLUSIONS : Diets high in fresh fruit and
salad vegetables appear protective against
cancer and
CVD . -
pubmed
The effects of
chloroquine on
bleeding time and disappearance of platelet
5 - hydroxytryptamine in
rabbits . -
pubmed
Bleeding times in
chloroquine - treated and control
rabbits were not significantly different ( 64.8 + /- 2.2 vs. 62.3 + /- 4.0 sec , respectively ) . -
pubmed
CONCLUSION :
Chloroquine prolongs platelet survival but does not affect
bleeding time in
rabbits . -
pubmed
Short term effect of continuous positive airway pressure on muscle sympathetic nerve activity in
patients with chronic
heart failure . -
pubmed
OBJECTIVE : To test the hypothesis that the short term application of continuous positive airways pressure ( CPAP ) increases muscle sympathetic nerve activity in
patients with
congestive heart failure . -
pubmed
PATIENTS : 10
patients with
congestive heart failure ( New York Heart Association functional class III ; mean ( SEM ) left ventricular ejection fraction 22 ( 1)% ) and 10 healthy subjects matched for age , sex , and weight . -
pubmed
Development of a reliable approach for prediction of environmental
disease not only will provide fundamental information regarding the genetic basis of
human disease but will be useful for reducing disease burden in the population and for advancing patient care . -
pubmed
Depressive symptoms and risk of functional decline and
death in
patients with
heart failure . -
pubmed
OBJECTIVES : We sought to examine whether
depressive symptoms are associated with poorer prognosis in
patients with
heart failure . -
pubmed
BACKGROUND :
Depression is an established risk factor for poor outcome in
patients with
coronary heart disease (
CHD ) . -
pubmed
Little is known of its role in
patients with
heart failure . -
pubmed
METHODS : We prospectively followed 391
patients & gt ; or = 50 years of age who met criteria for decompensated
heart failure on hospital admission . -
pubmed
CONCLUSIONS : An increasing number of
depressive symptoms is a negative prognostic factor for
patients with
heart failure , just as it is for patients with
CHD . -
pubmed
A case of acute
myocardial infarction associated with a mild blunt
thoracic trauma in a 60 - year - old
woman with normal coronary angiography is described . -
pubmed
METHOD AND DESIGN : Retrospective cohort study of 20,222
children aged 1 month to 18 years , receiving Medicaid , who had a first diagnosis of
gastroenteritis ,
diarrhea , or
vomiting between January 1 , 1998 , and December 31 , 1998 . -
pubmed
[ Study of the causes of
recurrence of
patients with
glottic cancer after partial laryngectomy ] . -
pubmed
OBJECTIVE : To study the causes of
recurrence of
patients with
glottic cancer after partial laryngectomy and to propose some possible measures for the prevention of
glottic cancer postoperative
recurrence . -
pubmed
METHOD : A retrospective review of consecutive 46
patients with recurrent
glottic cancer after partial laryngectomy was conducted . -
pubmed
RESULT : Among 46
patients diagnosed with
glottic cancer recurrence after partial laryngectomy , 32 cases were local
recurrences and 14 were regional
metastasis or local - regional
recurrences . -
pubmed
Artificial
caries lesions were produced on coronal dentin of extracted
human molars . -
pubmed
Analysis in
human fetuses and patients with
cryptorchidism . -
pubmed
We studied the distal insertions of the gubernaculum in
human fetuses and
patients with
cryptorchidism . -
pubmed
MATERIALS AND METHODS : We studied 326 gubernacula in 163
human fetuses at 10 to 35 weeks of gestation and 133 gubernacula in 101
patients with
cryptorchidism ( mean age 6.4 years ) . -
pubmed
CONCLUSIONS : The existence of anomalous insertions at the distal portion of the gubernaculum is rare in
human fetuses and patients with
cryptorchidism . -
pubmed
We found in
murine allogeneic bone marrow transplantation ( BMT ) models that recipients of alpha(4)beta(7)(- ) donor T cells had significantly less
graft - versus - host disease (
GVHD ) morbidity and mortality compared with recipients of alpha(4)beta(7)(+ ) donor T cells . -
pubmed
Effects of
thienopyridines ticlopidine and
clopidogrel on acute changes of these parameters in
patients with
NSTEACS are not well investigated . -
pubmed
METHODS :
Patients with
NSTEACS , treated with
aspirin and
unfractionated heparin ( n=37 , & lt;48 hours from
pain onset , Braunwald class IIIb ) were randomized to open
ticlopidine ( n=19 , 500 mg BID loading dose for 2 days and 250 mg BID for subsequent 5 days ) or no
ticlopidine ( n=18 ) . -
pubmed
Esophagitis impairs esophageal smooth muscle reactivity in the
rat model : an in vitro study . -
pubmed
All test
animals apart from the controls developed gross and histologic evidence of
esophagitis . -
pubmed
These changes may correspond to the functional motor
abnormalities of the esophagus seen in
patients with
reflux esophagitis . -
pubmed
We retrospectively identified all of the pediatric
patients with
Noonan syndrome seen at our institution and reviewed the ocular findings to determine specific ocular manifestations in pediatric
Noonan syndrome patients . -
pubmed
The muscle of the
obese Zucker
rat is highly
insulin resistant . -
pubmed
The purpose of this review is to discuss the cellular defects associated with the muscle
insulin resistance of the
obese Zucker
rat , as well as the mechanisms by which exercise training alleviates or compensates for these defects . -
pubmed
BACKGROUND : In the 2003 West Nile virus (
WNV ) epidemic , Colorado reported more
WNV cases than any other state , including an unprecedented number in organ transplant recipients . -
pubmed
All but 1 patient had a prodrome typical of
WNV encephalitis in nonimmunosuppressed
patients . -
pubmed
Ten
patients developed
meningoencephalitis , which in 3 cases was associated with
acute flaccid paralysis . -
pubmed
One
patient developed acute flaccid
paralysis without
encephalitis . -
pubmed
Six
patients had significant
movement disorders including
tremor ,
myoclonus , or
parkinsonism . -
pubmed
Magnetic resonance images of the brain were abnormal in 7 of 8 tested
patients , and electroencephalograms were abnormal in 7 of 7 , with 2 showing periodic lateralized
epileptiform discharges . -
pubmed
Nine of 11
patients survived
infection , but 3 had significant residual deficits . -
pubmed
One
patient died 17 days after admission , and autopsy findings revealed severe panencephalitic changes with multifocal areas of
necrosis in the cerebral deep gray nuclei , brainstem , and spinal cord as well as diffuse macrophage influx in the periventricular white matter . -
pubmed
A second
patient died of complications of
WNV encephalitis 6 months after hospital admission . -
pubmed
Zinc nutritional status and its relationships with
hyperinsulinemia in obese
children and adolescents . -
pubmed
A study was carried out in a group of
obese children and adolescents ( n=23 ) and compared to a control group ( n=21 ) , both between 7 and 14 yr of age . -
pubmed
As a result , considering that
zinc is part of the synthesis and secretion of this hormone , an assessment is necessary of the possible participation of the oligoelement in the mechanisms of
insulin resistance , commonly present in
obese patients . -
pubmed
Antigen - based therapies using ignored determinants of beta cell antigens can more effectively inhibit late - stage
autoimmune disease in
diabetes - prone
mice . -
pubmed
Using a panel of immunogenic peptides from various beta cell Ags , we evaluated the factors influencing the efficacy of
Ag - based therapies in
diabetes - prone NOD
mice with advanced disease . -
pubmed
CONTEXT : A 1990 National Institutes of Health Consensus Conference recommended that patients with stage III
colon cancer receive adjuvant chemotherapy because survival was improved in clinical trials in
patients who received a
5 - fluorouracil - based regimen . -
pubmed
CONCLUSIONS : Adjuvant chemotherapy use has increased from 1990 to 2002 for
patients with stage III
colon cancer with an associated increase in 5 - year survival of 16 % . -
pubmed
New options for adjuvant therapy in 2004 - 2005 may further improve the outcome of
patients with stage III
colon cancer . -
pubmed
In the
patients with diffusely severe
VAS ( & gt;70 % lumen reduction , the length of plaque & gt;1 cm or multiple plaques ) or localized critical VAS ( & gt;90 % lumen reduction ) diagnosed by TCDFI and confirmed with DSA , a narrowed and tortuous VA was demonstrated with minimal flow on color Doppler imaging and decreased 50 % of normal PSV and PSV & lt;0.30 m / s accompanied by slow early systolic acceleration on Doppler spectrum . -
pubmed
[
Hemangiosarcoma in a
dog ] . -
pubmed
Furthermore , it may be worth using FG in the observation of substituted eye movements in
patients with
horizontal gaze palsy due to a
pontine tegmental injury . -
pubmed
The study comprised 62
men with
ED : 16 neurogenic (
NGED ) , 15 arteriogenic (
AGED ) , 11 venogenic (
VGED ) and 22 psychogenic (
PGED ) . -
pubmed
OBJECTIVE : To compare the hemodynamic state , the severity and reversibility of
pulmonary arterial hypertension (
PAH ) in
patients with
Down ' s syndrome and
congenital heart disease (
CHD ) with respect to those without chromosomal pathologies . -
pubmed
MATERIAL AND METHODS : 30
patients with
congenital heart disease and left to right shunt were studied , corroborated by echocardiography ; 16
patients had
Down ' s syndrome and
CHD and the control group was constituted by 14
patients without
chromosomal abnormalities and with
CHD . -
pubmed
CONCLUSIONS : Although
patients with
Down ' s syndrome present
CHD with greater predisposition to develop irreversible
pulmonary arterial hypertension like common atrioventricular canal , the hemodynamic behavior of
pulmonary hypertension and during the challenge with
oxygen was similar in both groups . -
pubmed
Endovascular treatment of complicated
aortic aneurysms in
patients with underlying
arteriopathies . -
pubmed
Patients with
arteriopathies including
giant cell arteritis ,
Marfan syndrome , and
Takayasu ' s disease are at risk for
aneurysmal degeneration of the aorta . -
pubmed
The purpose of this study was to examine outcomes following endovascular stent graft ( EVSG ) repair of
aortic aneurysms in this
patient population . -
pubmed
Over an 8 - year period , 11
patients ( six
men , five
women ) with
arteriopathies underwent endovascular aortic repair . -
pubmed
EVSG repair of
aortic aneurysms is feasible and can be safely performed in
patients with
arteriopathies . -
pubmed
Long - term durability in this younger group of
patients who carry an ongoing risk of
arterial degeneration remains to be determined . -
pubmed
CASE REPORT : A 67 - year - old
female was referred for treatment of
chest wall pain following a T-12 compression
fracture . -
pubmed
The
patient experienced a rapid and complete
loss of sensation and movement below the T-10 level within five minutes after the injection . -
pubmed
PATIENTS AND METHODS : We conducted a retrospective review of
patients with pulmonary
metastases (
PM ) from
HCC who had undergone curative PM - ectomy at National Taiwan University Hospital between 1990 and 2004 . -
pubmed
CONCLUSION :
Patients with longer DFIs and fewer
PMs can benefit from PM - ectomy in
HCC . -
pubmed
( 1 ) For
patients with
hypercholesterolaemia requiring primary or secondary prevention ,
pravastatin ,
simvastatin and
atorvastatin have a proven benefit in terms of mortality and/or morbidity . -
pubmed
Hepatotoxic effects occur in about 2 % of
patients , especially in those using high daily doses or sustained - release formulations . -
pubmed
Vestibular rehabilitation in a
patient with
whiplash - associated disorders . -
pubmed
In this paper , the comprehensive treatment of a
patient with
whiplash - associated disorders is presented . -
pubmed
A 71 - year - old
woman was admitted to our hospital due to unilateral leg
edema . -
pubmed
In
patients with well - defined
syndrome of
chronic mesenteric and gastric ischemia or with exercise - induced
pain , good results can be expected with division of the median arcuate ligament with open celiac artery reconstruction . -
pubmed
Laparoscopic division of the median arcuate ligament followed by celiac artery stenting is an effective , minimally invasive technique to manage selected
patients with
celiac artery compression syndrome . -
pubmed
A fast , geometric beam angle optimization ( BAO ) algorithm for clinical intensity - modulated radiation therapy ( IMRT ) was implemented on ten localized
prostate cancer patients on the Radiation Therapy Oncology Group ( RTOG ) 0126 protocol . -
pubmed
Dialysis therapy has the same rules for
diabetic and non - diabetic
patients . -
pubmed
Tolerance to ultrafiltration is lower and haemodynamic instability is easier to provoke in
diabetics than in non - diabetic
patients . -
pubmed
Customized , specifically designed and targeted intervention in
diabetic patients may slow down the progression of
diabetic vascular changes , improve
diabetes compensation and the
patients ' quality of life . -
pubmed
A water deprivation test was developed for the differentiation of
polyuric disorders in birds using the racing
pigeon as a model . -
pubmed
For a period of 3 days of food and water deprivation , urine and plasma osmolalities and
body weight of 40 clinically healthy racing
pigeons were monitored . -
pubmed
Muscle action potentials in
human poliomyelitis before and after treatment by Billig 's method . -
pubmed
We describe here one such young male
patient with
unilateral lacrimal gland swelling . -
pubmed
Patient is well and has no other manifestation or
recurrence of the disease during a follow - up of 24 months . -
pubmed
Abnormal fMRI Connectivity in
Children with
Dyslexia During a Phoneme Task : Before But Not After Treatment . -
pubmed
Brains of 18
children with
dyslexia ( 5
girls , 13
boys ) and 21 and without
dyslexia ( 8
girls , 13
boys ) were scanned before and after the
children with
dyslexia received instructional treatment . -
pubmed
Children with
dyslexia had greater functional connectivity from the left inferior frontal gyrus seed point to the right inferior frontal gyrus than did the
children without
dyslexia . -
pubmed
Compared to adults with and without
dyslexia who differed in bilateral connectivity from left inferior frontal gyrus on the same task , the
children with and without
dyslexia differed in left side connectivity from left inferior frontal gyrus . -
pubmed
At Time 2 after treatment , the
children with
dyslexia , who had participated in a three - week instructional program that provided explicit instruction in linguistic awareness , alphabetic principle ( taught in a way to maximize temporal contiguity of grapheme - phoneme associations ) , decoding and spelling , and a writers ' workshop , did not differ from the children without
dyslexia in any of the clusters in the group difference map identifying differences between dyslexics and good readers , showing that functional connectivity ( and not just regions of interest ) may normalize following instructional treatment . -
pubmed
Effect of oral
erythromycin therapy in
patients with
aseptic loosening of joint prostheses . -
pubmed
We recruited 32
AL patients . -
pubmed
AL patients were treated with either EM ( 600 mg / day , n=18 ) or placebo ( n=14 ) daily , started one month before surgery and ending on the day of surgery . -
pubmed
Our results suggest that EM represents a biological cure or prevention for those
patients who might need repeated revision surgeries and/or show the early signs of progressive
osteolysis after TJR . -
pubmed
Possible modulating action of plant infusion of
Ocimum sanctum L. on
chromosomal aberrations and sister chromatid exchanges induced by
chlormadinone acetate in
human lymphocytes in vitro . -
pubmed
The aim of the present study is to study the anti- genotoxic activity of the plant infusion against the CMA induced
genotoxic damage on cultured
human lymphocytes , using
chromosomal aberrations and sister chromatid exchanges ( SCFs ) as parameters . -
pubmed
The results of the present study suggest that the plant infusion per se does not have genotoxic potential , but can modulate the
genotoxicity of
chlormadinone acetate in
human lymphocytes in vitro . -
pubmed
Diary and patient - reported outcomes in
patients with severe
overactive bladder switching from
tolterodine extended release 4 mg / day to
solifenacin treatment : An open - label , flexible - dosing , multicentre study . -
pubmed
METHODS : VERSUS was a 12 - week , open - label , flexible - dosing study assessing the efficacy , tolerability and effects on health - related quality of life ( HRQOL ) of
solifenacin in
patients with
OAB . -
pubmed
The PPBC scale and
Overactive Bladder Questionnaire ( OAB - q ) assessed
patient - reported outcomes . -
pubmed
CONCLUSION : In
patients with severe
OAB symptoms ,
solifenacin was effective and well tolerated . -
pubmed
Solifenacin improved urgency ,
incontinence , micturition frequency ,
nocturia and nocturnal voids in
patients continuing to experience
urgency episodes on
tolterodine ER 4 mg / day . -
pubmed
Patients experienced improvements in HRQOL and perceived bother from
OAB . -
pubmed
We performed a single - institution phase II study to evaluate the efficacy and
toxicities of
vinorelbine monotherapy in
patients previously treated with
anthracyclines and
taxanes . -
pubmed
Grade 3 or 4 hematologic toxicities included
neutropenia in 18
patients ( 69.2 % ) and
anemia in four
patients ( 15.3 % ) . -
pubmed
Grade 1 or 2
peripheral neuropathy was observed in 11
patients ( 42.3 % ) , however there were no cases of grade 3 or 4
peripheral neuropathy . -
pubmed
The results of this study indicate that
vinorelbine monotherapy was feasible regimen with manageable
toxicities in
patients with metastatic
breast cancer who were previously exposed to
anthracyclines and
taxanes . -
pubmed
The severity of chronic
cerebrospinal venous insufficiency in
patients with
multiple sclerosis is related to altered cerebrospinal fluid dynamics . -
pubmed
The aim of this study was to investigate the relationship between a Doppler cerebral venous hemodynamic insufficiency severity score ( VHISS ) and cerebrospinal fluid ( CSF ) flow dynamics in 16
patients presenting with
CCSVI and relapsing - remitting
MS (
CCSVI - MS ) and in eight healthy controls ( HCs ) . -
pubmed
This study demonstrates that venous outflow disturbances in the form of CCSVI significantly impact on CSF pathophysiology in
patients with
MS . -
pubmed
albicans cells , with obvious differences between cells recovered from culture and those from a
murine model of disseminated
candidiasis . -
pubmed
Oral
phosphate binders in
patients with
kidney failure . -
pubmed
HIV drug resistance testing is recommended as routine part of clinical practice in HIV /
AIDS treatment and care . -
pubmed
Postural control of
mouth breathing school aged
children regarding gender . -
pubmed
BACKGROUND : Postural control of
mouth breathing school aged
children . -
pubmed
Our data suggest that intermediate - risk
ERMS is driven by a common set of genomic defects , a finding that has important implications for the application of targeted therapies to improve the treatment of
children diagnosed with this disease . -
pubmed
The effect of
metoprolol alone and combined
metoprolol -
felodipin on the digital microcirculation of
patients with primary
Raynaud ' s syndrome . -
pubmed
METHODS : We enrolled in this study 46
patients suffering from both
hypertension and primary
Raynaud ' s syndrome . -
pubmed
PARTICIPANTS : Caregivers of children with
motor disabilities completed an interview survey for
children 0 - 21 years . -
pubmed
Efficacy and safety of
entecavir in clinical practice in treatment - naive Caucasian
chronic hepatitis B patients . -
pubmed
METHODS : We retrospectively analysed data from 190 nucleos(t)ide - naive
chronic hepatitis B patients treated with
entecavir ( 0.5 mg / day ) in 25 Spanish centres . -
pubmed
Thirty - four per cent of the
patients who underwent biopsy had advanced
fibrosis /
cirrhosis . -
pubmed
METHODS : Retrospective case series was taken to study the clinical data of 15
patients ( 30 eyes ) diagnosed with
Takayasu ' s arteritis at Peking Union Medical College Hospital from 1992 to 2010 . -
pubmed
Two
patients recognized by initial presentation of
impaired vision prior to the diagnosis of
Takayasu ' s arteritis . -
pubmed
Six cases were classified as
brachiocephalic arteritis , and 9
patients belonged to extensive
arteritis . -
pubmed
The first symptom in some
patients can be
impaired vision . -
pubmed
BACKGROUND :
Mycoplasma pneumoniae (
Mp ) frequently colonizes the airways of patients with
chronic asthma and likely contributes to
asthma exacerbations . -
pubmed
CONCLUSION : The therapy of TRAE combined with cryoablation contributes to reduce the percentage of Treg cells and improve the immune situation of
patients with
renal cell carcinoma , which consequently increase
tumor necrosis rate and prolong the
patients ' survival duration . -
pubmed
PGI ( 2 ) analogs have been used effectively in primary
pulmonary hypertension in
adults and have shown promise in
PPHN . -
pubmed
Study of treatment using percutaneous acetabuloplasty and interstitial implantation of
( 125 ) I seeds for
patients with metastatic
periacetabular tumors . -
pubmed
METHODS : A retrospective analysis was performed on 24
patients with
metastatic periacetabular tumors who underwent combined therapy of percutaneous acetabuloplasty and interstitial implantation of
( 125 ) I seeds between February 2003 and June 2011 . -
pubmed
Complete
pain relief was achieved in 58 % ( 14 of 24 ) of
patients , and
pain reduction was achieved in the 42 % remaining ( 10 )
patients . -
pubmed
Pain recurred in one
patient 3 months after surgery . -
pubmed
Comparing the KPS , Harris and VAS scores pre- and postoperativelyat 1 , 6 , and 12 months , the combined therapy method was significantly effective in metastatic periacetabular
tumor patients ( P<0.05 ) . -
pubmed
CONCLUSIONS : Percutaneous cementoplasty with interstitial implantation of
( 125 ) I seeds is an effective treatment method for metastatic
periacetabular tumor patients , providing
tumor resistance ,
pain relief , increased bone stability , and improved quality of life for
patients . -
pubmed
We present a case of acute
oxalate nephropathy in a
patient with underlying
systemic lupus erythematosus who recently received intravenous
vitamin C. -
pubmed
Clinical and polysomnographic features of
patients with
multiple system atrophy in Southwest China . -
pubmed
PURPOSE : The association between clinical features and polysomnographic variables of Chinese
patients with
multiple - system atrophy (
MSA ) remains largely unknown . -
pubmed
METHODS : This study assessed 30
patients with
MSA from Southwest China using the Unified Multiple - System Atrophy Rating Scale ( UMSARS ) . -
pubmed
RESULTS : Of the 30
patients , 23 ( 76.7 % ) were classified as having
MSA - C and seven ( 23.3 % ) were diagnosed with
MSA - P. -
pubmed
Twenty - one
patients complained of
sleep disorders . -
pubmed
Twenty - one
patients had
obstructive sleep apnea . -
pubmed
CONCLUSIONS : Various
sleep disorders are common in Chinese
MSA patients . -
pubmed
House finch populations differ in early inflammatory signaling and pathogen tolerance at the peak of
Mycoplasma gallisepticum infection . -
pubmed
Periodontitis is an inflammatory disease of
microbial origin , resulting in devastation of the tooth supporting apparatus . -
pubmed
There is miniscule literature regarding the contribution of AGE to
periodontal disease in
patients with
DM . -
pubmed
Dibenzoyl and isoflavonoid glycosides from
Sophora flavescens : inhibition of the
cytotoxic effect of
D - galactosamine on
human hepatocyte
HL-7702 . -
pubmed
Compounds 1 , 2 , 13 , 14 , and 19 exhibited weak inhibition of the
cytotoxic effect of
d - galactosamine on the
human hepatic cell line
HL-7702 . -
pubmed
MicroRNAs define distinct
human neuroblastoma cell phenotypes and regulate their differentiation and tumorigenicity . -
pubmed
BACKGROUND :
Neuroblastoma (
NB ) is the most common extracranial
solid tumor in
children . -
pubmed
Resting - state brain activation correlates with short - time antidepressant treatment outcome in drug - naive
patients with
major depressive disorder . -
pubmed
OBJECTIVE : A resting - state functional magnetic resonance imaging study ( fMRI ) to investigate pretreatment regional differences in brain function , in
patients with early treatment responsive ( ERD ) and early treatment nonresponsive ( END )
major depressive disorder (
MDD ) . -
pubmed
METHODS :
Patients with
MDD and healthy control
subjects underwent fMRI . -
pubmed
Brain activity in
patients with
ERD ( n = 26 ) differed from those with
END ( n = 30 ) in the lingual gyrus and cerebellum . -
pubmed
There was a significantly correlation between activity in these regions and disease duration in
patients with
ERD , and with amelioration of
depressive symptoms in
patients with
END . -
pubmed
A preemptive management approach to
patients at high risk of
relapse is more effective . -
pubmed
SUMMARY : Allogeneic haematopoietic stem cell transplantation is curative in up to 40 % of
myelodysplastic syndrome patients . -
pubmed
Biopsy Gleason score & gt;= 8 was the most common cause for classification of
patients into the high - risk
PCa group . -
pubmed
Prediction of
coronary artery disease in
patients with
lower extremity peripheral artery disease . -
pubmed
Coronary artery disease (
CAD ) is a major determinant of long - term prognosis in
patients with
peripheral artery disease (
PAD ) . -
pubmed
We investigated the predictors of
CAD in
patients with lower extremity PAD.A total of 107
patients with
PAD who underwent peripheral and simultaneous coronary angiography were reviewed . -
pubmed
The prevalence of
CAD in
patients with
PAD was 62 % ( 67/107 ) , and of this 62 % , only 13 % ( 9/67 ) had
angina and 72 % ( 48/67 ) had multi - vessel disease . -
pubmed
The
patient experienced
convulsions , and the 24 - h ambulatory electroencephalography results showed abnormalities , but the electromyography results were normal . -
pubmed
OBJECTIVES :
Cytotoxic effects of obturation materials were tested in presence and absence of endotoxin on
human monocytes in vitro . -
pubmed
BACKGROUND : Breast surgery compromises one of the most common
cancer surgeries in
females and commonly followed by acute
postoperative pain . -
pubmed
We assumed that
pregabalin and
ketamine can be used in control of
postoperative pain in female
patients undergoing
breast cancer surgery . -
pubmed
All
patients received general anesthesia and after recovery , the three groups were assessed in the first postoperative 24 h for postoperative visual analog scale ( VAS ) , total 24 h
morphine consumption , incidence of
postoperative nausea and vomiting (
PONV ) , sedation score & gt;2 and any complications from the drugs used in the study . -
pubmed
Safety , efficacy , and pharmacokinetics of
navitoclax (
ABT-263 ) in combination with
erlotinib in
patients with advanced
solid tumors . -
pubmed
This phase I study ( NCT01009073 ) evaluated the safety , pharmacokinetics , and preliminary antitumor activity of
navitoclax combined with
erlotinib in
patients with advanced
solid tumors . -
pubmed
Patients with documented
cancers for whom
erlotinib therapy was appropriate received
erlotinib 150 mg orally once daily plus
navitoclax 150 mg orally once daily , with
navitoclax dose escalation via a continuous reassessment method model . -
pubmed
RESULTS : Eleven
patients were enrolled , including six
patients with
nonsmall cell lung cancer . -
pubmed
Dose - limiting
toxicities , most commonly
diarrhea , were observed in 4
patients . -
pubmed
The respiratory DC / macrophage network at steady - state and upon
influenza infection in the
swine biomedical model . -
pubmed
Human and
mouse respiratory tracts show anatomical and physiological differences , which will benefit from alternative experimental models for studying many
respiratory diseases . -
pubmed
Pig has been recognized as a valuable biomedical model , in particular for lung transplantation or pathologies such as
cystic fibrosis and
influenza infection . -
pubmed
Interestingly ,
porcine moDCs increased in the lung upon
influenza infection , as observed in the
mouse model . -
pubmed
METHODS : Two groups of
patients were screened retrospectively over a 5 - year period for the inclusion criterion of severe
retrobulbar hematoma after retrobulbar or parabulbar injection . -
pubmed
Although
osteoarthritis can affect all joints ,
knee osteoarthritis is the most common type among
adolescents . -
pubmed
We established a new ' transmission kinetic assay ( TKA ) ' to quantify the
human cytomegalovirus (
HCMV ) transmission between cells in vitro and to phenotypically characterize
HCMV strains based on their mode of transmission by flow cytometric analysis . -
pubmed
Autologous hematopoietic stem cell transplantation ( HSCT ) is a very effective treatment option for
patients with severe
systemic sclerosis (
SSc ) . -
pubmed
As transfection efficiency in some primary and established cells is low ,
lentivirus based expression systems with high
infection rates can improve experimental design . -
pubmed
We provide detailed protocols for the generation of
CSC293Ts and for the production of
lentivirus for
CSC infection using
glioblastoma as a model . -
pubmed
MATERIAL AND METHODS : A total of 32
participants with
edentulism were included . -
pubmed
We have validated this method in a chemo - genetic
zebrafish model of dopaminergic
neuron degeneration . -
pubmed
Pseudomonas aeruginosa and
Aspergillus fumigatus are the leading bacterial and fungal pathogens in
cystic fibrosis (
CF ) . -
pubmed
Patients with
beta thalassemia major may develop a specific
osteoarthropathy as they approach the second and third decades of life . -
pubmed
Twenty - five of 50
patients between the ages of 5 and 33 years had evidence of
periarticular disease that consisted of dull - aching
ankle pain exacerbated by weight bearing and relieved by rest . -
pubmed
Acute
toxicity of
phosphate ester mixtures to
invertebrates and
fish . -
pubmed
Studies of
human semen in topical
corticosteroid - treated and in
methotrexate - treated
psoriatics . -
pubmed
Ejaculates were studied from ten
men with severa
psoriasis treated with topical
corticosteroids and from ten similar
patients who had received
methotrexate therapy from 1 to 9 years . -
pubmed
The effect of acupuncture needling in hindlimb points on the threshold of
pain arising from the radiant heat applied to the snout of the
rabbit has been evaluated both before and after various surgical lesions produced in the spinal cord . -
pubmed
Fibroblasts from affected and unaffected skin sites of
patients with
PSS and from normal adult skin were cultured in the presence of various
human sera or conditioned media . -
pubmed
Serum and peritoneal fluid from
women with and without evidence of
endometriosis were tested for the presence of antibodies against endometrial tissue antigens with Western blot analysis . -
pubmed
The
patients with
endometriosis had serum antibodies against 34 - kd endometrial cytosolic antigen , which was not present in serum from fertile women without
endometriosis . -
pubmed
The peritoneal fluid from
patients with
endometriosis also reacted with 34 - kd endometrial antigen but not the peritoneal fluid from control fertile women . -
pubmed
Percutaneous cardiopulmonary support system ( PCPS ) was applied for a 85 years old
man with
circulatory collapse caused by left ventricular free wall blow out
rupture following acute
anterior myocardial infarction . -
pubmed
The
patient was transferred to operating room and closure of the
ventricular rupture was performed under the usual cardiopulmonary bypass . -
pubmed
Adult ( 2 to 3 months old ) hypophysectomized
rats were treated intratesticularly with increasing doses of
5 alpha - dihydrotestosterone (
DHT ; 10 - 200 micrograms/100 g
body weight ) or vehicle ( 50 microliters
dimethyl sulphoxide ;
DMSO ) in the contralateral testis . -
pubmed
[ Pharmacological support in dental treatment of
hemophiliac patients ] . -
pubmed
During a 4 - year period , 83 pregnant
women with
fetal choroid plexus cysts were investigated in our unit . -
pubmed
The effect of
magnesium sulphate (
MgSO4 ) infusion on blood pressure and circulating venous
catecholamine levels in 8
patients with severe
gestational proteinuric hypertension is described . -
pubmed
The literature mentions its occurrence in
patients subjected to aortic valve replacement who have
low cardiac output and in
patients undergoing myocardial revascularization . -
pubmed
A randomized clinical study of
patients with advanced
epithelial ovarian cancer after debulking surgery showed that high - dose ( 120 mg / m2 )
cis - platinum (
DDP ) in combination with
cyclophosphamide ( 600 mg / m2 ) had a significantly higher response and survival rate than the low - dose
DDP ( 60 mg / m2 ) and
cyclophosphamide combination . -
pubmed
Though moderate to severe marrow
toxicity was evident in 80 % of the
patients in the high - dose group and 40 % of the low - dose group , no serious
sepsis or
death developed as a result of the marrow
depression . -
pubmed
Mild
neurotoxicity was observed in 55 % of the
patients in the high - dose group and only 20 % in the low - dose group . -
pubmed
Mild
nephrotoxicity was seen in 25 and 17 % of
patients in the high- and low - dose groups , respectively . -
pubmed
However , it should only be used in institutions with supportive facilities in the management of
patients with severe marrow
depression . -
pubmed
The effect of selective intracoronary antiarrhythmic drug infusion on inducibility of
cardiac arrhythmias was studied in 3
patients with recurrent sustained monomorphic
ventricular tachycardia referred for comprehensive electrophysiologic studies . -
pubmed
Each
patient had evidence of prior
myocardial infarction , 1 or more occluded coronary arteries and a readily identifiable collateral vessel that provided collateral flow to the
infarct - related artery . -
pubmed
In each
patient , the clinical
arrhythmia was reproducibly inducible by programmed stimulation in the control state . -
pubmed
In each
patient the clinical
arrhythmia was rendered noninducible during selective intracoronary drug infusion . -
pubmed
On follow - up , four
patients had died of their disease , one developed
recurrence and
pulmonary metastases , one was free of disease after 4 years , and one is a recent case . -
pubmed
Chemotherapy protocols may need to be altered to include
sarcoma - oriented drugs for this particular group of
patients . -
pubmed
A placebo - controlled , double - blind study of 63
inpatients with
major affective disorder was performed to compare the safety and efficacy of
fluvoxamine and
imipramine . -
pubmed
Although low - dose soluble
aspirin can be recommended as a useful anti -
thrombotic drug regimen in
patients with
vascular disease , enteric - coated preparations have a theoretical advantage for
aspirin preparations which are to be ingested daily for many years . -
pubmed
The intense antifibrillatory and antiarrhythmic actions of
GS 015 , a derivative of the novel structure series of the
5 -( beta - aminoacyl )- 3 - carbalkoxyamino - iminodibenzyles , are demonstrated on models of
myocardial ischaemia : antifibrillatory action on the acute
coronary occlusion in the conscious
rat ( 1.0 mg / kg i.v . ) -
pubmed
The substance seems suitable for preventing terminal
arrhythmias in
patients with
ischaemic heart disease as well as for treating
arrhythmias in the acute stage of
myocardial infarction . -
pubmed
The
patient also presented with
oesophageal diverticulum and
hiatal hernia . -
pubmed
Electron microscopic study of leucocytic infiltration of the mammary teat duct during
infection with
Staphylococcus aureus . -
pubmed
Leucocytic response to
Staphylococcus aureus infection was observed in the
bovine mammary teat duct using transmission electron microscopy . -
pubmed
Dermal connective tissue in
patients with
chronic obstructive airways disease . -
pubmed
Electron microscopic study of spontaneous
mammary carcinomas in
cats and
dogs : virus - like particles in
cat mammary carcinomas . -
pubmed
[ 2 cases of
purulent meningitis caused by
Neisseria flavescens in the same environment ] . -
pubmed
Pronounced stimulation of
citrate metabolism by
glutamate was demonstrated in 12 of 13
strains of
N. - pubmed
meningitidis tested and only 1 of 6
strains of
N. - pubmed
The remaining
strains of
N. - pubmed
Insulin resistance in genetically
obese ,
hyperglycemic mice . -
pubmed
A case of
abomasal inpaction in a
cow . -
pubmed
[ Current status of diet and drug therapy of
diabetes mellitus in
children ] . -
pubmed
Sixty - one were
atopic and 15 had
anaphylaxis due to
bee stings or drugs . -
pubmed
A series of 47
children with
absence seizures was analysed retrospectively . -
pubmed
Fourteen of these
children also had other types of
seizures , and four had repeated episodes of
absence status . -
pubmed
A 100 % reduction in
seizure frequency was achieved in 38
children ( 80.8 % ) . -
pubmed
VPA was superior in the treatment of
children who had EEG polyspikes or
absence status . -
pubmed
A
seizure reduction of 50 % to 75 % was achieved in 7
children ( 14.9 % ) . -
pubmed
Two
patients ( 4.3 % ) had refractory
seizures . -
pubmed
A transient
Stevens - Johnson syndrome occurred in a
patient treated with
ESM . -
pubmed
Objective evidence of antitumor activity was seen in
non - Hodgkin ' s lymphoma ,
chronic lymphocytic leukemia ,
Hodgkin ' s disease ,
breast cancer , and
melanoma , indicating that IFL - rA , the first genetically engineered biological response modifier available for testing in
cancer patients , is biologically active in vivo . -
pubmed
Among 35
patients ,
abortion occurred spontaneously or was performed electively in 25.7 % , and 71 % of the remainder underwent delivery before 37 weeks . -
pubmed
We concluded that perinatal outcome has significantly improved for
diabetic women with
nephropathy . -
pubmed
History and physical examination in
acute pulmonary embolism in
patients without preexisting
cardiac or pulmonary disease . -
pubmed
The history and physical examination were assessed in 215
patients with
acute pulmonary embolism uncomplicated by preexisting
cardiac or pulmonary disease . -
pubmed
[
Rat brain
gangliosides under the combined effect of
hypercapnia ,
hypoxia and
hypothermia ] . -
pubmed
This study describes the regional distribution in the
canine atria of electrophysiologic effects induced by stimulation of the right and left cervical vagosympathetic complexes , the right atrial ganglionated plexus , and the right and left stellate
ganglia . -
pubmed
To quantify the dose - response relation of irritant - induced
erythema , we examined
inflammation in
human skin after application of an irritant , using perpendicular polarized photography and diffuse reflectance spectroscopy as compared to clinical visual scoring . -
pubmed
Yet in groups at high risk for
HIV serology is not sufficient because of the window period between
infection and seroconversion . -
pubmed
These new assays to detect
HIV immunity enable us to identify two new groups among seronegative , at risk individuals ; namely those with immunity to
HIV and a detectable
HIV infection ( silent carriers ) , and those with immunity and no proof of
infection . -
pubmed
Most importantly ,
rat - derived NK cells were functional in both YAC
tumor cytolysis and ADCC assays , suggesting that the xenogeneic
mouse host environment was sufficient to support the generation , maturation , and function of
rat - derived NK cells . -
pubmed
Evaluation of cell
death in
EBV - transformed lymphocytes using
agarose gel electrophoresis , light microscopy and electron microscopy . -
pubmed
Recently we treated several
patients with limited
facial injuries in which the nasoethmoidal complex " greensticks . " -
pubmed
Could serum
HBV DNA level in the early phase of
acute hepatitis B predict evolution to chronic
HBV carriage ? -
pubmed
By using this analytical method ,
MTIC was quantified in plasma of
cancer patients ( n=12 ) within 0.25 - 12 h after oral administration of
temozolomide at 150 mg / m2 . -
pubmed
The
subjects consisted of 20
patients with
skull - base meningiomas , and were classified into a preoperative embolized group and a non - embolized group . -
pubmed
Apoptotic cell
death in
patients with
sepsis ,
shock , and
multiple organ dysfunction . -
pubmed
OBJECTIVES : The purpose of this study was to determine whether apoptosis is a major mechanism of cell
death in
patients with
sepsis . -
pubmed
DESIGN : A prospective study of 20
patients who died of
sepsis and
multiple organ dysfunction was performed . -
pubmed
The control group of 16
patients consisted of
critically ill , nonseptic
patients who were evaluated either prospectively ( 7 ) or retrospectively ( 9 ) . -
pubmed
In addition ,
normal colon sections from seven
patients who had bowel resections were included . -
pubmed
PATIENTS :
Critically ill patients . -
pubmed
Indirect evidence of lymphocyte apoptosis in septic
patients included extensive depletion of lymphocytes in white pulp and a marked
lymphocytopenia in 15 of 19
patients . -
pubmed
There were no significant differences in the overall incidence or treatment of
intracranial hypertension between
patients who were treated with therapeutic
hypothermia and normal controls . -
pubmed
Therapeutic
hypothermia maintained the ICP at lower levels during the cooling phase , but once
patients were rewarmed , the ICP elevated to the levels of normothermic
patients . -
pubmed
The absence of cardiac and circulatory function causes severe
edema in
amphibian embryos . -
pubmed
Mechanical
hyperalgesia was measured as paw withdrawal threshold ( PWT ) in response to a mechanical stimulus in two
animal models of persistent
pain ; ( 1 ) 24 h following subplantar injections of Freund 's complete adjuvant ( FCA ) into the left hind paw or ( 2 ) 11 - 15 days following a partial ligation of the left sciatic nerve . -
pubmed
In
patients with severe
MTHFR deficiency , a metabolite(s ) other than hyperhomocyst(e)
inemia also appears to be associated with its clinical manifestation in
cerebrovascular disease . -
pubmed
Semen and serum pharmacokinetics of
zidovudine and
zidovudine - glucuronide in
men with
HIV-1 infection . -
pubmed
STUDY OBJECTIVE : To characterize the concentration - time profiles of
zidovudine and
zidovudine - glucuronide in semen and serum of
men infected with the
human immunodeficiency-1 virus (
HIV-1 ) . -
pubmed
PATIENTS : Four asymptomatic
HIV-1 - infected men . -
pubmed
A 60 - year - old
man underwent anterior resection for advanced rectal
carcinoma . -
pubmed
The
patient remained disease - free for 10 months postoperatively , until multiple
lung metastases appeared . -
pubmed
We conclude that
patients with solitary adrenal
metastasis may benefit from surgical resection and that resection could be considered as a therapy for solitary adrenal
metastasis from
colorectal carcinoma . -
pubmed
The process of interaction of the Choachi
strain of
Trypanosoma rangeli with intestinal epithelial cells of
Rhodnius prolixus was analyzed in experiments carried out in vitro and in vivo . -
pubmed
A case of disseminated
infection with
Pichia ohmeri . -
pubmed
Multiple locations of
ESBC were observed in seven
patients ( 20 % ) . -
pubmed
Local
recurrence was observed within 4 years in 10
patients ( 28 % ) . -
pubmed
CONCLUSION : Our results suggest that cryotherapy is an effective method of treatment in
patients with
ESBC . -
pubmed
MATERIALS AND METHODS : To analyse a case of a
patient suffering from this
congenital malformation , her progressive clinical state , the surgical approach . -
pubmed
a 42 - year - old
woman , suffers from a
cerebello - spino - medullar disturbance responsible for a major dependence and
respiratory insufficiency with a risk of
death . -
pubmed
BACKGROUND : A recent Intergroup trial demonstrated a significant survival advantage of postgastrectomy chemoradiation in
gastric cancer patients , primarily because of a reduction of a relative locoregional
recurrence ( LRR ) rate exceeding 70 % in control
patients . -
pubmed
METHODS : Information on
patients undergoing gastrectomy for potentially curable
gastric cancer between 1990 and 2000 was reviewed . -
pubmed
The effect of stimulus duration on the mismatch negativity of the auditory event - related potentials was studied in healthy
children and those with
attention - deficit symptoms . -
pubmed
Similar analysis of
human mesothelioma tumor tissue showed that , with few exceptions , receptor gene expression was substantially less than that for the carrier gene . -
pubmed
Our studies have , for the first time , suggested that
alcohol consumption alone does not lead to the development of marked
liver necrosis ( at least in the
rat ) , but rather that a second insult is required for this to occur . -
pubmed
Total antioxidant capacity was determined using
oxygen absorbance capacity assay ( ORAC ) in serum of
patients suffering from
depression ,
schizophrenia ,
Alzheimer ' s disease (
AD ) ,
anorexia nervosa ,
Parkinson ' s disease (
PD ) ,
amyotrophic lateral sclerosis (
ALS ) ,
Aids - encephalopathy ,
diabetic polyneuropathy (
PNP ) ,
cardiomyopathy (
CM ) ,
renal disease , and healthy individuals as controls ( C ) . -
pubmed
In serum of
patients with
renal disease significantly elevated antioxidant capacity was found . -
pubmed
Decrease of serum antioxidant capacity in
patients with
anorexia nervosa and
Aids - encephalopathy are probably due primarily to
malnutrition and secondly to insufficient antioxidant and immune system . -
pubmed
There was only 1 ( 4 % )
intraoperative complication , which occurred in the second
patient operated on with this procedure . -
pubmed
Concerning the technique , we believe that LAO with intact spermatic vessels could be considered the treatment of choice in the
patient with
IAT , as it does not affect normal testicular vascularization . -
pubmed
Patients presenting for initial access evaluation in contemporary practice are less likely to have arteries and veins suitable for native
fistula (
AVF ) formation in the classic location . -
pubmed
Seasonal changes in the physiology of male
Virginia opossums (
Didelphis virginiana ): signs of the
Dasyurid semelparity syndrome ? -
pubmed
Treatment of
human and experimental
anthrax with
tetracycline . -
pubmed
PALMITATE UTILIZATION IN OBESE -
HYPERGLYCEMIC MICE . -
pubmed
Human tumor transplants in
hamsters : their usefulness in the study and treatment of
patients with
cancer . -
pubmed
METHODS AND RESULTS : One hundred ninety - eight
guinea pigs ( 850 - 1,050 g ) received 30 episodes of
ventricular fibrillation followed by transthoracic defibrillation . -
pubmed
Health education , mass chemotherapy and the sanitary disposal of faeces have been the traditional mainstays of
hookworm control , but more recently chemotherapy targeted only to heavily infected individuals who appear predisposed to
hookworm anaemia has emerged as a realistic alternative . -
pubmed
Continuous muscle stretch prevents disuse
muscle atrophy and deterioration of its oxidative capacity in
rat tail - suspension models . -
pubmed
The objective of this report is to emphasize the efficacy of the
oxaliplatin/
5 - fluorouracil /
leucovorin regimen ( FOLFOX-4 ) in three
patients presenting oncologic emergencies secondary to advanced
colon cancer . -
pubmed
The first case was a 40 - year - old
man with severe
respiratory insufficiency due to massive carcinomatous
lymphangitis ; subsequently a cecal
adenocarcinoma was diagnosed . -
pubmed
The second case was a 41 - year - old
woman presenting with
fever ,
abdominal mass and
pain . -
pubmed
The
patient 's condition deteriorated with
intestinal obstruction secondary to the large left liver mass . -
pubmed
The third case was a 58 - year - old
woman presenting with
hepatic mass ,
fever and
weight loss . -
pubmed
These cases demonstrate that even
patients with advanced
colorectal cancer presenting with oncologic emergencies and life - threatening conditions can be successfully treated with the FOLFOX-4 regimen . -
pubmed
A microscopic
itch mite (
Pyemotes herfsi ) was identified as the likely cause of the outbreak , which affected an estimated 54 % of the Crawford County population ( 2000 population : 38,242 ) . -
pubmed
In vivo , we compared the
bone resorption and bone formation response to T3 in
ADOI patients and age- and sex - matched controls . -
pubmed
We report a 53 - year - old
man , with an unusual phenotype of
CTX . -
pubmed
Vibrio parahaemolyticus , a gram - negative marine bacterium , is an important pathogen causing
food - borne gastroenteritis or
septicemia . -
pubmed
Recent genome sequencing of the RIMD2210633
strain ( a Kanagawa phenomenon - positive clinical isolate of
serotype O3 : K6 ) revealed that the
strain has two sets of gene clusters that encode the type III secretion system ( TTSS ) apparatus . -
pubmed
To match the
patients with
IP and unique
patients with
OP , logistic regression was used to develop a propensity score . -
pubmed
Patients with
IP were matched to unique
patients with
OP with an identical 5 - digit propensity score . -
pubmed
METHODS :
Homocysteine concentrations were measured in 30
XFS /
XFG patients and 18 age matched controls . -
pubmed
In
XFS /
XFG patients homocysteine concentration was significantly elevated ( unpaired t test , p = 0.023 ) , and CCA stiffness was higher ( p<0.05 ) , while
strain , cross sectional compliance coefficient , distensibility , and BRS were significantly reduced compared to the controls ( Mann - Whitney U test , p< ; or = 0.013 for each parameter ) . -
pubmed
Effect of linear polarized light irradiation near the stellate
ganglion in skin blood flow of fingers in
patients with progressive
systemic sclerosis . -
pubmed
OBJECTIVE : The purpose of this study is to evaluate the effect of linear polarized light irradiation near the stellate
ganglion area on cutaneous blood flow in fingers of
patients with progressive
systemic sclerosis . -
pubmed
BACKGROUND DATA :
Sympathetic overactivity is known to be present in
patients with
progressive systemic sclerosis . -
pubmed
METHODS : Five
patients with
progressive systemic sclerosis and three normal healthy controls were studied . -
pubmed
RESULTS : No significant alternations of the skin blood flow between normal controls and
patients with progressive
systemic sclerosis after linear polarized light irradiation were detected . -
pubmed
The effect of linear polarized light on the microcirculation of
patients with progressive
systemic sclerosis was minimal and transient . -
pubmed
CONCLUSION : The effect of linear polarized light in treating
patients with progressive
systemic sclerosis may not result from the improvement of skin blood flow . -
pubmed
A 65 - year - old
woman with a
left occipital lobe tumor . -
pubmed
[ Analysis of
postoperative complications of radical hysterectomy for 219
cervical cancer patients ] . -
pubmed
OBJECTIVE : To analyze the causes and therapeutic approaches for the complications of radical hysterectomy plus pelvic lymphadenectomy in
cervical cancer patients . -
pubmed
RESULTS : a total of 49
patients ( 22.4 % ) developed
postoperative complications . -
pubmed
The
patients in the group treated by radical hysterectomy plus pelvic lymphadenectomy was likely to develop
postoperative complication compared with the
patients in the group by modified radical hysterectomy plus pelvic lymphadenectomy ( 24.0 % versus 0 , P = 0.067 ) . -
pubmed
The
postoperative complication incidence in the
patients who had preoperative neoadjuvant chemotherapy through intra - arterial catheter or radical radiotherapy in the other hospitals were 50.0 % ( 2/4 ) and 100.0 % ( 1/1 ) , which were higher than that of the
patients treated primarily in our hospital ( 21.3 % , 25.3 % ) though without statistically significant difference among the groups . -
pubmed
On the example of a 5 - year longitudinal study of a
boy who suffered severe
traumatic brain injury , it is shown that there seems to be no limit as to the repair of the injured central nervous system ( CNS ) if Schalow Coordination Dynamics Therapy is administered . -
pubmed
This study examined
asthma morbidity in relation to mold , cockroach , dust mite , and
cat allergens in the homes of 61 low - income Chicago children with
asthma . -
pubmed
Spontaneous polymorphic
ventricular tachycardia after administration of
pilsicainide in a
patient resuscitated from
ventricular fibrillation . -
pubmed
We performed a
pilsicainide challenge test in a 38 - year - old
man who was resuscitated from
ventricular fibrillation without apparent baseline electrocardiogram ( ECG ) abnormality . -
pubmed
Low
selenium levels have been associated with
anemia in animals , but this relationship has not been well characterized in
humans . -
pubmed
METHODS : One eye each of 40 healthy
subjects , 48
glaucoma patients , and six
patients with
ocular hypertension were measured with SLP - VCC and CSLO . -
pubmed
Four
glaucoma specialists , four general ophthalmologists , four
residents in ophthalmology , and four optometrists classified the ONH photographs as normal or
glaucomatous . -
pubmed
Role of
pre - infarction angina and inflammatory status in the extent of
microvascular obstruction detected by MRI in
myocardial infarction patients treated by PCI . -
pubmed
Our study aimed to investigate the incidence and the influencing factors of MVO in
patients with
ST - elevation myocardial infarction (
STEMI ) treated by primary percutaneous intervention ( PCI ) . -
pubmed
PATIENTS , METHODS : Using contrast - enhanced MRI ,
microvascular obstruction was defined as early hypoenhancement . -
pubmed
50
patients ( 56+/-11 years ) with
STEMI underwent PCI . -
pubmed
RESULTS :
Microvascular obstruction ( score 1 to 3 ) was observed in 90 % of the
patients and major
microvascular obstruction ( score 2 - 3 ) in 54 % . -
pubmed
Water stress augments
silicon - mediated resistance of susceptible
sugarcane cultivars to the stalk borer
Eldana saccharina ( Lepidoptera : Pyralidae ) . -
pubmed
All
patients were
women , aged 52 to 63 years and presented with single or
multiple pulmonary nodules . -
pubmed
The study cohort comprised 64
FMF patients who were classified as attack - free
patients ( Group 1 ; n = 34
patients , aged 3 - 19 years ) and attack
patients ( Group 2 ; n = 30
patients , aged 3 - 21 years ) . -
pubmed
Inflammation with increased acute phase reactants continued during both attack and attack - free periods in
FMF patients . -
pubmed
METHODS : We developed a modified model of chronic antigen - induced
arthritis (
AIA ) in
mice with a strong bias toward
inflammation . -
pubmed
RESULTS : In this novel model of
AIA ,
mice developed organized
ectopic lymphoid follicles with topologically segregated B cell and T cell areas , high endothelial venules , and germinal center formation within the chronically inflamed synovial tissue . -
pubmed
For example , knowledge of the pathways involved in the development of
endothelial dysfunction or in endothelial repair associated with bone marrow - derived cells -- a common feature of a number of cardiovascular conditions -- could lead to treatments that are able to stimulate endothelial replacement with circulating progenitor cells in
patients with
pulmonary arterial hypertension of whatever etiology . -
pubmed
Follow - up PET scans were negative for
abdominal malignancy in 38
patients . -
pubmed
Thirty - five of these 38
patients with negative follow - up PET were proven to be without
abdominal malignancy , with a negative predictive value of 92.1 % ( 35 of 38 ) . -
pubmed
Fifteen of these 17
patients with a positive follow - up PET scans were found to have
malignancy in the abdomen with a positive predicative value of 88.2 % ( 15 of 17 ) . -
pubmed
All 4
patients with indeterminate follow - up scans were proven not to have
malignancy . -
pubmed
We studied 99
patients discharged from the department between March and December 2002 with a
HF diagnosis and samples of cTnI. -
pubmed
Patients with
acute coronary syndromes ,
myocarditis or
renal failure were excluded . -
pubmed
We report the clinical and molecular characteristics of 6 new
patients with
recessive hereditary methemoglobinemia due to
cytochrome b5 reductase deficiency . -
pubmed
One
patient was affected by
Type - II disease with
cyanosis and severe progressive
neurological dysfunction , whereas the others displayed the benign Type - I phenotype . -
pubmed
The RNA alphavirus
Semliki Forest ( SFV ) triggers apoptosis in various mammalian cells , but it has remained controversial at what
infection stage and by which signalling pathways host cells are killed . -
pubmed
The recombinant
strain of
Bacillus subtilis bearing
B. - pubmed
METHODS : The study included 21
patients ( 12
males , 9
females ; mean age 45 years ; range 19 to 72 years ) with
tennis elbow . -
pubmed
The
patients were evaluated with a
pain score ( 0 to 10 points ) and clinical examination before and one month after treatment . -
pubmed
RESULTS : Complete or near - complete relief of
pain and unlimited function were obtained in four
patients ( 40 % ) in group 1 , and in 10
patients ( 90.9 % ) in group 2 . -
pubmed
On physical examination , two
patients ( 20 % ) in group 1 and eight
patients ( 72.7 % ) in group 2 were
pain - free upon pressure on the lateral epicondyle or dorsiflexion of the wrist . -
pubmed
OB glue paste technique for establishing nude
mouse human gastric cancer orthotopic transplantation models . -
pubmed
METHODS : Using OB glue paste technique , orthopic transplantation models were established by implanting
SGC-7901 and
MKN-45 human gastric cancer cell strains into the gastric wall of
nude mice . -
pubmed
The biological behaviors of the nude
mouse human gastric cancer orthotopic transplantation models established with this technique are similar to the natural processes of growth and
metastasis of
human gastric cancer , and , therefore , can be used as an ideal model for experimental research of proliferative
metastasis of
tumors . -
pubmed
BACKGROUND : Bariatric surgery achieves long - term
weight loss in obese
adults with amelioration of
diabetes and
hypertension . -
pubmed
RESULTS : The baseline ( preoperative ) mean age was 46 years , 82 % were
women , 26 had a blood pressure of & gt ; or = 140/90 mm Hg , and 25 had
type 2 diabetes . -
pubmed
Selection for
body weight at 49 day of age ( s and h , downward selected lines ; s ' and h ' , upward selected lines ) affected reproductive traits in CF1
mice lines . -
pubmed
In general , 25 % of the
patients develop
metastasis . -
pubmed
None of these
patients developed
metastasis . -
pubmed
Seventeen
patients were described to have
melanocytic schwannoma of the skin or subcutaneous tissues . -
pubmed
Two of the three
patients showed
metastatic disease , one of them died of disseminated
metastases . -
pubmed
Owing to the lack of clinical trials , we recommend that
patients be treated according to the existing guidelines for
melanoma . -
pubmed
The first and most important action on encountering a patient with unexplained
gastric or duodenal ulceration is to double check that they are truly
H. - pubmed
Visual impairment was considered absent in 87
patients ; mild in 52 ; moderate in 17 ; and 22
patients were legally blind . -
pubmed
The results clearly demonstrate that it is possible to perform a complete evaluation of visual function and ocular health in the elderly institutionalized
patient , independent of age , cognitive status , or
communication disorders . -
pubmed
METHODS : A cross - sectional survey with serological testing for
HIV ,
syphilis ,
HBV and
HCV through long - chain referral sampling strategy to help control the bias generated from non - statistic sampling . -
pubmed
Supplementation with
cholecalciferol does not improve glycaemic control in
diabetic subjects with normal serum
25 - hydroxyvitamin D levels . -
pubmed
CONCLUSIONS : We were not able to demonstrate that
vitamin D supplementation had a significant effect on
glucose metabolism in
subjects with
type 2 diabetes but without
vitamin D deficiency . -
pubmed
Further studies are needed in larger groups of
subjects with
type 2 diabetes or
impaired glucose tolerance , who also exhibit low serum
25 - hydroxyvitamin D levels . -
pubmed
The DNA - DNA hybridization value between
strain YIM 65188 ( T ) and
S. - pubmed
is proposed , with
YIM 65188 ( T ) (= CCTCC AA 208020(T ) = DSM 41942(T ) ) as the type
strain . -
pubmed
Virus infection is one of the major threats to
human health and can be avoided by minimizing exposure to infectious viruses . -
pubmed
Image - based non - destructive methods were used to quantify root growth reactions happening within hours following simulated leaf herbivore attack.1 The induction of
wound reactions in leaves of seedlings of
Nicotiana attenuata led to transiently decreased root growth rates : Upon application of the oral secretions and regurgitants of the specialist herbivore
Manduca sexta , a transient decrease in root growth was observed that was more pronounced than if a mere mechanical wounding was imposed . -
pubmed
MATERIALS AND METHODS : A total of 750
children of rural areas in the age group of 6 - 10 years were examined , using WHO index , to record the prevalence of
dental caries and treatment needs . -
pubmed
To evaluate the clinical usefulness of noninvasive positive pressure ventilation ( NPPV ) in liver transplant recipients , we established application criteria for NPPV in respiratory management in these
patients , as follows : ( 1 ) arterial
oxygen tension to fraction of inspired
oxygen ratio less than 300 and arterial
carbon dioxide tension greater than 45 mm Hg ; ( 2 ) arterial
oxygen tension to fraction of inspired
oxygen ratio less than 200 ; ( 3 ) respiratory rate greater than 25 / min ; and ( 4 ) presence of severe
atelectasis or
pulmonary edema . -
pubmed
In 1
patient , reintubation was required because of deterioration of respiratory function due to
systemic infection . -
pubmed
OBJECTIVE : To search for novel autoantibodies in
patients with
rheumatoid arthritis (
RA ) in an effort to better understand the processes of joint destruction in this disease . -
pubmed
METHODS : A 25 - year - old
woman , without medical or familiar history for
hypertension or
cerebrovascular diseases , underwent a normal spontaneous delivery with neonatal
birth weight of 2340 g ( 9th percentile ) . -
pubmed
Eight days later the
patient presented sudden
headache and generalized
tonic - clonic seizures . -
pubmed
FYX-051 showed a potent and long - lasting
hypouricemic effect in a
rat model of
potassium oxonate - induced
hyperuricemia , and it seems to be a promising candidate for the clinical treatment of
hyperuricemia . -
pubmed
Of the 23
patients studied , 18 presented the cardiac form and five presented the cardiodigestive form of
Chagas disease . -
pubmed
Echinocandin lock therapy could significantly enhance the management of
candidiasis in
patients with indwelling catheters by combating biofilms and enabling device maintenance in situ . -
pubmed
We examined the effects of
cisplatin , an anti -
cancer drug , on HCs of the inner ear and on HCs and support cells ( SCs ) of neuromasts in
zebrafish using transmission and scanning electron microscopy . -
pubmed
Usefulness of serial determination of
Aspergillus galactomannan in the diagnosis and management of invasive
aspergillosis in an
AIDS patient with
non - Hodgkin lymphoma . -
pubmed
GAG storage in untreated
MPS I dogs was significantly different from normal
dogs in all examined sections . -
pubmed
GAG levels in normal
dogs varied by region : frontal lobe ( mean : 2.36 + - 0.54 mug / mg protein ) , cerebellum ( 2.67 + - 0.33 ) , basal ganglia and thalamus ( 3.51 + - 0.60 ) , hippocampus ( 3.30 + - 0.40 ) , and brainstem ( 3.73 + - 1.10 ) . -
pubmed
METHODS : Twenty - two
patients who had been treated previously with cannulated screws or dynamic hip screw for
femoral - neck fracture and progressed to
nonunion were treated with revision internal fixation using an angle blade plate and autogenous nonvascularised fibular graft . -
pubmed
Mean
patient age was 38 ( range 21 - 52 ) years , with average duration between
injury and revision surgery 11.2 m ( range 8 - 16 months ) . -
pubmed
Patients with poor results included one with
nonunion and other with
avascular necrosis with collapse of the femoral head . -
pubmed
Ranolazine injection into coronary or femoral arteries exerts marked , transient regional vasodilation without systemic
hypotension in an intact
porcine model . -
pubmed
This report describes a
patient presenting with recurrent
acute renal failure occurring in the course of
POEMS syndrome , a
multisystem disease associated with
plasma cell dyscrasia . -
pubmed
This case report describes a 52 - year - old
woman with a 10 - year history of underlying
systemic lupus erythematosus with minimal
proteinuria who developed sudden onset of
nephrotic syndrome . -
pubmed
Silent
peripheral arterial disease in
patients admitted to the emergency room . -
pubmed
Detection during preclinical stages ( silent ) may help to identify
individuals and populations at risk ( elderly
patients ) for
atherothrombotic disease (
stroke or coronary ) . -
pubmed
Subacute toxicity assessment of carotenoids extracted from
citrus peel ( Nanfengmiju ,
Citrus reticulata Blanco ) in
rats . -
pubmed
The mixture of carotenoids extracted from
citrus peel ( Nanfengmiju ,
Citrus reticulata Blanco ) was tested for subacute
oral toxicity . -
pubmed
In this study , dose levels of 0 , 200 , 500 and 2000 mg / kg
body weight / day were administered by gavage to 10
Wistar rats / sex / group for 28 days . -
pubmed
These findings suggested that the
No - Observed - Adverse - Effect Level for the mixture of carotenoids extracted from
citrus peel was at least 2000 mg / kg
body weight / day . -
pubmed
Neuroimaging , biochemical and cellular evidence of protection by
mycophenolate mofetil on
middle cerebral artery occlusion induced
injury in
rats . -
pubmed
Therefore , the present study was designed to evaluate the effect of
mycophenolate mofetil (
MMF ) on the
cerebral ischemic injury in the
middle cerebral artery occlusion (
MCAo ) model in
rats . -
pubmed
One hour after
MCAo , the
animals were treated with
MMF ( 50 , 100 , 200mg / kg , i.p . ) -
pubmed
The efficacy and safety of
lixivaptan in
outpatients with
heart failure and
volume overload : results of a multicentre , randomized , double - blind , placebo - controlled , parallel - group study . -
pubmed
This study assessed
weight loss after 1 day and 8 weeks of treatment with
lixivaptan in
outpatients with
HF and
volume overload . -
pubmed
CONCLUSIONS : In
outpatients with
HF and
volume overload ,
lixivaptan 100 mg once daily , when added to standard therapy , reduced
body weight , improved
dyspnoea and
orthopnoea , and was well tolerated . -
pubmed
BACKGROUND & amp ; AIMS : New treatment approaches are needed for
patients with
pancreatic adenocarcinoma . -
pubmed
Direct lipid extraction from wet
Chlamydomonas reinhardtii biomass using osmotic
shock . -
pubmed
Osmotic
shock treatment was applied directly to wet
Chlamydomonas reinhardtii biomass with water content & gt;99 % , along with both polar and non - polar organic solvents . -
pubmed
Outcome of
patients with
localized orbital sarcoma who relapsed following treatment on Intergroup
Rhabdomyosarcoma Study Group ( IRSG ) Protocols - III and -IV , 1984 - 1997 : a report from the
Children 's Oncology Group . -
pubmed
RESULTS : Twenty - four of 188
patients ( 12.8 % ) developed local ( n = 22 ) or distant
relapse ( n = 2 ) at 0.057 - 7.05 years ( median , 1.58 ) after enrollment . -
pubmed
After
recurrence ,
patients underwent orbital exenteration ( n = 10 ) , enucleation ( 2 ) ,
tumor excision ( 3 ) , or biopsy ( 1 ) ; 7 had no operation , and 1 had no data . -
pubmed
Two
patients died ; one at 1.79 years after contralateral brain
metastasis followed by local
recurrence , and another at 2.49 years after multiple local
recurrences . -
pubmed
Twenty - two
patients ( 91.7 % ) survived
sarcoma - free for 0.04 - 17 years ( median , 6.9 ) after
relapse , and 18 of 22 ( 82 % ) were alive & gt;=5 years after
relapse . -
pubmed
No mechanism exists to predict accurately the risk of
recurrence in
patients with
PA following successful gross total surgical resection . -
pubmed
METHODS : A multicentre , retrospective cohort study of
patients admitted for
leg ulceration between 1996 and 2007 was conducted . -
pubmed
The aims of this study were to investigate the long - term course and biological behavior of orthotopically implanted
C6 gliomas and to dynamically monitor the distribution of superparamagnetic
iron oxide ( SPIO ) nanocomposite - labeled
C6 glioma cells in
rats using 7.0 T MRI . -
pubmed
DESIGN : This cross - sectional study included 151
children and adolescents 8 - 17 years old with
NS from 16 participating institutions in North America . -
pubmed
OBJECTIVE : To evaluate the retraction technique for urinary catheterization of
women with
Type III female genital mutilation (
FGM ) . -
pubmed
METHODS : Male
rats randomized into four groups ( n = 12 ): control ,
diabetic , control +
resveratrol , and
diabetic +
resveratrol . -
pubmed
Nephropathy is a common consequence of
diabetes , with a high prevalence in
patients with type 1 ( 15%-25 % ) and
type 2 diabetes mellitus (
T2DM ; 30%-40 % ) . -
pubmed
The ongoing advances in
T2DM therapy may allow optimization of glycemic control in a wide range of
patients , thereby helping to reduce the increasing morbidity and mortality associated with
diabetic nephropathy . -
pubmed
INTRODUCTION :
Alveolointerstitial involvement is a common manifestation in
patients with connective tissue disorders . -
pubmed
MATERIAL AND METHODS : Thirty one consecutive
patients with a suspected diagnosis of
rheumatoid lung involvement were examined with high resolution transthoracic ultrasonography for detecting of ultrasonographic comet tail signe as a ultrasonographic marker of lung involvement in alveolointerstitial involvement in
rheumatoid lung disease and the results of them were compared with High resolution computed tomography as gold standard method for diagnosis of lung involvement in this
patients . -
pubmed
Until now , these procedures have been reserved for low - risk
patients and are rarely offered to
patients with advanced
disease where neoadjuvant chemotherapy and postmastectomy radiation are a planned part of the treatment . -
pubmed
CONCLUSIONS : SSM and NSSM have been offered to
patients with relatively low - risk
breast cancer as oncologically safe while affording superior cosmesis with one - step immediate reconstruction . -
pubmed
Our series demonstrates that either procedure can be offered to
patients with more advanced
cancers requiring postoperative RT . -
pubmed
Neonatal colonization of germ - free
mice with
Bifidobacterium longum prevents
allergic sensitization to major birch pollen allergen Bet v 1 . -
pubmed
longum might be a promising candidate for perinatal intervention strategies against the onset of
allergic diseases in
humans . -
pubmed
UNLABELLED : Neoadjuvant
sunitinib might downsize unresectable
renal cell carcinoma (
RCC ) and enable nephrectomy in a subset of
patients . -
pubmed
After neoadjuvant
sunitinib in 27
RCC patients ,
tumors were resected in 13
patients . -
pubmed
INTRODUCTION : In
patients with locally advanced and metastatic
RCC , selection criteria for nephrectomy are imprecise . -
pubmed
CT scans of unresectable primary
RCCs before and after neoadjuvant
sunitinib were retrospectively reviewed to identify radiographic features associated with
patient selection for surgery . -
pubmed
PATIENTS AND METHODS : CT scans of 27
patients with
RCC ( 31
tumors ) treated with neoadjuvant
sunitinib were performed as part of a prospective clinical trial . -
pubmed
After neoadjuvant
sunitinib ,
tumors were surgically resected in 13
patients ( 17
tumors ) and not resected in 14
patients ( 14
tumors ) . -
pubmed
Eligible
patients had to be over 16 years of age , consulted within 72 hours for a
trauma , and available for outpatient follow - up at 2 , 7 , and 14 days posttrauma . -
pubmed
OBJECTIVE : The aim of this study was to evaluate the detection rate accuracy of Double - balloon Enteroscopy ( DBE ) after Capsule Endoscopy ( CE ) in
patients with suspected
small bowel diseases . -
pubmed
METHODOLOGY : From January 2009 to March 2012 , sixty - two
patients with obscure
small bowel diseases who underwent CE followed by DBE were included in this study . -
pubmed
Furthermore , the detection rate of
small bowel diseases in
patients with obscure small intestinal
bleeding using CE + DBE ( 90.9 % , 30/33 ) was superior to that of CE ( 78.8 % , 26/33 ) ; chi(2)=1.8857 , P>0.05 . -
pubmed
Using of CE followed by DBE is effective in the diagnosis and management of
patients with obscure
small bowel diseases . -
pubmed
The most common indication for 1 - step
PEG placement was
swallowing dysfunction in
children with
neurological impairment ( 49 % ) . -
pubmed
Direct - acting antiviral agents in
patients with
hepatitis C cirrhosis . -
pubmed
Patients with
cirrhosis who are
infected with hepatitis C virus (
HCV ) are the most in need of antiviral treatment . -
pubmed
Tissue damage on the ocular surface of
patients with
RA is autoimmune - mediated . -
pubmed
False - positive
fluorodeoxyglucose positron emission tomography results after chemotherapy in
patients with
metastatic seminoma . -
pubmed
MATERIALS AND METHODS : Between July 2003 and September 2013 we performed 305 PC - RPLNDs in 277
patients , 22 because of
metastatic seminoma . -
pubmed
In 1
patient , there was uncertainty whether the initial retroperitoneal
tumor contained
choriocarcinoma elements . -
pubmed
In 4 of 7
patients , intraoperative or
postoperative complications occurred ( polar artery ligation with functional loss , bilateral non - nerve - sparing technique with retrograde ejaculation , ureteral replacement with an ileal segment , and
pulmonary embolism ) . -
pubmed
CONCLUSION : In
patients with
metastatic seminoma who received chemotherapy ,
FDG - PET is a valuable tool to evaluate whether the residual mass contains viable
tumor tissue or only
necrosis . -
pubmed
,
patients with
ureteral compression ,
patients with high risk of
recurrence , or
patients with unclear initial histology ) . -
pubmed
There was one late
noncardiac death and 73
patients returned for angiography ( 82 % ) , thus 12 additional
patients were lost to follow - up at 1 year . -
pubmed
METHODS : Thirty
participants with
acute stroke who were enrolled in inpatient rehabilitation and had
cognitive impairments were randomized to receive strategy training ( n = 15 , 10 sessions as adjunct to usual inpatient rehabilitation ) or reflective listening ( n = 15 , same dose ) . -
pubmed
In Taiwan , the first
human - infecting H6N1
avian influenza virus was isolated in 2013 . -
pubmed
We report on a 17 - year - old female
patient with
hypertrichosis on the lumbosacral area since birth that was later diagnosed with tethered cord in magnetic resonance imaging . -
pubmed
We present the case of a 18 year - old
man with
abdominal pain ,
nausea and
hematemesis , the endoscopy showed polypoid
tumor bleeding of 5 cm in gastric antrum . -
pubmed
The aim of this study was to investigate the effect of early vessel recanalization on clinical outcome in
patients with large - vessel occlusion
stroke . -
pubmed
METHODS : This is a single - center cohort study , analyzing prospectively collected data on 152
patients with large - vessel occlusion and
acute ischemic stroke . -
pubmed
RESULTS : Early recanalization was an independent predictor of a good clinical outcome in only those
patients who presented with a severe
ischemic stroke ( National Institutes of Health
Stroke Scale [ NIHSS ] score & gt;15 ; P = .017 ) . -
pubmed
This was not the case for less severe
strokes ( NIHSS score & lt;= 15 ) where recanalization did not lead to more
patients with functional independence at 90 - day follow - up ( P = .21 ) . -
pubmed
CONCLUSIONS : In this study of acute large - vessel occlusion
stroke , we found that clinical outcome following early recanalization was dependent on the
patient 's pretreatment NIHSS score . -
pubmed
A non - negligible proportion of
patients with milder
strokes did well despite persistent large - vessel occlusion . -
pubmed
These results may suggest that in
patients who are able to maintain adequate collateral flow despite proximal
arterial occlusion , effective adaptive mechanisms are present , which for some
patients are long - lasting . -
pubmed
BACKGROUND :
Trichomoniasis , caused by
Trichomonas vaginalis , is the most common
sexually transmitted disease (
STD ) in the world with estimates of 7 - 8 million
infections annually in the United States and 180 million globally . -
pubmed
PURPOSE : Radiotherapy ( RT ) is used frequently in
patients with
melanoma , but results are suboptimal because the disease is often radioresistant . -
pubmed
Additionally ,
athymic mice with
D04 flank
tumours were treated with fractionated RT after gavage with
trametinib and monitored for
tumour growth . -
pubmed
Mice receiving the combination treatment (
trametinib 1mg / kg and RT over 3 days ) showed a reduced mean
tumour volume compared with
mice receiving
trametinib alone ( p=0.016 ) , or RT alone ( p=0.047 ) . -
pubmed
Ultrastructural pathological features of unilateral
renal artery stenosis in the
rats . -
pubmed
In this study , we aimed to investigate histopathological characteristics in a
rat model of
RAS . -
pubmed
AIM : To analyze the expression of proapoptotic molecules in
patients with
lupus erythematosus discoid and
lupus profundus . -
pubmed
OBJECTIVE :
Patients with
subarachnoid haemorrhage (
SAH ) often require multidisciplinary management and their treatment is difficult to standardize . -
pubmed
A nationwide registry to assess the overall management of
patients treated for
SAH would be useful to further investigate patients with
SAH . -
pubmed
MATERIALS AND METHODS : Consecutive
men undergoing radical prostatectomy for histologically confirmed
prostate cancer were analyzed . -
pubmed
This paper reports a 25 - year follow - up of a
patient with
Clouston syndrome , from childhood to adulthood , monitoring diagnosis and clinical course of the disease . -
pubmed
Current treatment options for
hepatitis C patients co - infected with
HIV . -
pubmed
With the availability of all - oral , direct acting antivirals ( DAAs ) ,
hepatitis C virus (
HCV ) therapy has been revolutionized for
HIV / HCV co - infected patients . -
pubmed
Indeed
HCV cure rates are now no longer different between
HCV mono and HIV / HCV co - infected persons and are both greater than 95 % . -
pubmed
In
HIV / HCV co - infection however , drug interactions between
HIV and
HCV agents need be checked prior to starting
HCV therapy . -
pubmed
Acute Effect of Intravenous
Sildenafil on Cerebral Blood Flow in
Patients with
Vasospasm After
Subarachnoid Hemorrhage . -
pubmed
We recently demonstrated that it could improve
cerebral vasospasm (
CVS ) in
humans after
SAH . -
pubmed
METHODS : Six
subjects with angiographically confirmed
CVS received 30 - mg of intravenous
sildenafil ( mean 9 + - 2 days after
aneurysmal SAH ) . -
pubmed
PURPOSE : Measures derived from longitudinal
tumour size data have been increasingly utilised to predict survival of
patients with solid
tumours . -
pubmed
The aim of this study was to examine the prognostic value of such measures for
patients with metastatic
pancreatic cancer undergoing
gemcitabine therapy . -
pubmed
CONCLUSIONS : A parametric model that incorporates model - derived
tumour shrinkage metrics in addition to other baseline variables could predict reasonably well survival of
patients with metastatic
pancreatic cancer . -
pubmed
Artemisinin - Resistant
Plasmodium falciparum Malaria . -
pubmed
Our primary outcome was survival of
OHCA patients at the end of ED stay . -
pubmed
Here , we present the IND enabling preclinical rodent studies in support of clinical testing of
vesicular stomatitis virus (
VSV ) as a systemic therapy . -
pubmed
Efficacy studies showed dose - dependent
tumor regression in
C57BL / KaLwRij mice bearing syngeneic
5TGM1 plasmacytomas after systemic VSV administration . -
pubmed
These findings suggest that active
CMV infection in the setting of treated
HIV may represent an attractive potential target for therapeutic intervention . -
pubmed
METHODS : Ninety - five
patients with
IBS and 276 healthy controls were enrolled in the study . -
pubmed
However , the response to treatment is not as robust as is seen in
osteoporosis , and it seems less effective in certain types of
OI , and in adult
OI patients as compared to most pediatric cases . -
pubmed
In this review , we will summarize the recent findings regarding the pharmacological and biological strategies for the treatment of
patients with
OI . -
pubmed
The clinical characteristics and antibody levels were compared between
patients with (
seizure group ) and without
seizures ( non -
seizure group ) . -
pubmed
RESULTS : The non -
seizure and
seizure groups comprised 173 and 29
patients , respectively . -
pubmed
From the clinical point of view , it is important to be aware that
patients with
microtia must obtain also appropriate diagnostic imaging studies of the craniovetebral junction due to eventual concomitant occipitalization of the atlas and frequently associated
C1 - C2 instability . -
pubmed
On the basis of the results , the researchers concluded that
Tribulus terrestris can be used as a safe therapeutic alternative to current modalities for the management of
motility dysfunction in males . -
pubmed
Cervical artery dissection , including carotid artery and
vertebral artery dissection , is associated in at least 20 % of young adult
patients with
stroke . -
pubmed
PATIENT CONCERNS : We reported 2
patients who complained of
dizziness and
pain , the findings of US confirmed the presence of extracranial
vertebral artery dissection . -
pubmed
OUTCOMES : The
patients were diagnosed of
vertebral artery dissection by US . -
pubmed
Testing of a novel percutaneous temporary aortic valve in a
rabbit model of acute severe
aortic regurgitation : an experimental study . -
pubmed
The redesigned membrane - based TAV prototype is evaluated in a
rabbit model of acute severe
aortic regurgitation . -
pubmed
Eight
rabbits of
body weights ranging 4.9 - 5.4 kg were randomly assigned to two groups : those received additional hemodynamic support with the TAV prototype immediately after
aortic regurgitation was induced versus no TAV support . -
pubmed
RESULTS : Comparing the groups with TAV versus without
TAV , the mean
body weights were similar : 4.99 + - 0.06 vs. 5.10 + - 0.22 kg ( p = 0.71 ) . -
pubmed
CONCLUSIONS : In a
rabbit model of acute massive
aortic regurgitation , the use of the TAV support prototype did not hasten the animals '
death , but rather survival may be enhanced by the use of the device . -
pubmed
Atheroprotective effects of statins in
patients with
unstable angina by regulating the blood - borne microRNA network . -
pubmed
The present study investigated the protective role of statins in
patients with
unstable angina (
UA ) by regulating the circulating miRNA network . -
pubmed
miRNA array results demonstrated that there were 21 differentially expressed miRNAs in non - statin - treated
patients with
UA ( n=8 ) compared with non -
coronary artery disease controls ( n=8 ) , and 33 differentially expressed miRNAs in statin - treated
patients with
UA ( n=8 ) compared with non - statin patients . -
pubmed
This study aimed to explore the effects of two siderophore - producing bacterial
strains on
iron absorption and plant growth of
peanut in calcareous soil . -
pubmed
Two siderophore - producing bacterial
strains , namely ,
YZ29 and
DZ13 , isolated from the rhizosphere soil of
peanut , were identified as
Paenibacillus illinoisensis and Bacillus sp . -
pubmed
Therefore , YZ29 and
DZ13 can be used as candidate bacterial
strains to relieve
chlorosis of
peanut and promote
peanut growth . -
pubmed
PATIENTS : One hundred eighteen
patients who sustained combat - related
upper extremity amputations between October 2001 and December 2011 . -
pubmed
CASE : A 28 - year - old
woman with
neurofibromatosis type 1 and
acromegaly presented with absent breast development despite hormone therapy . -
pubmed
Examination noted a normally developed
woman with
acromegalic features and
Tanner stage I breasts . -
pubmed
After attempting hormone therapy ,
patients with
absent thelarche should be evaluated for
congenital breast anomalies ,
estrogen receptor abnormalities , or gene defects . -
pubmed
To investigate the effect of removal of cerebrospinal fluid by lumbar " tap test " on the cerebral circulation in
patients with
iNPH , 14
patients with " probable "
iNPH were studied using a novel blood tracking technique based on blood oxygenation level - dependent ( BOLD ) magnetic resonance signal intensity . -
pubmed
BACKGROUND :
Delirium is a common and severe problem for hospitalised
patients , with occurrence ranging from 14%-56 % , morbidity and mortality from 25%-33 % . -
pubmed
METHODS : The
bite force of 345
patients was measured with a
bite force recorder ; impressions of the shape and size of the oral tori were taken on plaster models prior to orthodontic treatments . -
pubmed
We present a case of a 54 - year - old
man who had been followed - up for
ankylosing spondylitis and presented with
pain in the shoulder and pelvic girdles ,
restricted movement , and
morning stiffness for 2 months . -
pubmed
Methods A total of 136
patients ( type 1 : n = 47 , type 2 : n = 89 ) who enrolled in the study were diagnosed based on the Japanese Diabetes Society diagnostic criteria for
diabetes mellitus . -
pubmed
paratuberculosis (
Map ) exposed bulls of which four were intratracheally infected with a Belgian field
strain of
M. - pubmed
Map exposure did not interfere with the development of
SIT in
M. - pubmed
Chitosan - based nanoformulated
( -)- epigallocatechin-3 - gallate (
EGCG ) modulates
human keratinocyte - induced responses and alleviates
imiquimod - induced
murine psoriasiform dermatitis . -
pubmed
We investigated and compared the efficacy of nanoEGCG versus native or free
EGCG in vitro and in an in vivo
imiquimod ( IMQ)-induced
murine psoriasis - like
dermatitis model . -
pubmed
The in vivo relevance and efficacy of nanoEGCG formulation ( 48 microg /
mouse ) were assessed in an IMQ - induced
mouse psoriasis - like
skin lesion model compared to free
EGCG ( 1 mg /
mouse ) . -
pubmed
Background :
Mycoplasma hominis is often present in the amniotic cavity with microbial invasion associated with spontaneous
preterm labor . -
pubmed
Methods : Amniotic fluid samples were collected from 65 pregnant
women ( age range : 25 - 45 years ) previously followed at an
infertility clinic . -
pubmed
Postoperative outcomes were evaluated , with a focus on the effects of portal vein resection and resected liver volume on remnant liver regeneration in
patients with
liver tumors . -
pubmed
Preventive Effect of
Garlic Oil and Its
Organosulfur Component
Diallyl - Disulfide on Cigarette Smoke - Induced
Airway Inflammation in
Mice . -
pubmed
The aim of this study was to explore the preventive effect of
garlic oil ( GO ) and its
organosulfur component
diallyl disulfide (
DADS ) on cigarette smoke ( CS)-induced
airway inflammation . -
pubmed
Anti - Carcinogenic
Glucosinolates in Cruciferous
Vegetables and Their Antagonistic Effects on Prevention of
Cancers . -
pubmed
RESULTS : Of 315
patients screened , 49 ( 15.5 % ) were randomized ( 26 to early palliative care ; 23 to the control group ) ; aged ( mean + - SD ) 71 + - 8 years ; FEV1 was 37 + - 14 % predicted ; 88 % with a
COPD assessment test score & gt ; 10 ; 69 % on long - term
oxygen therapy or home noninvasive ventilation . -
pubmed
To characterize compatible plant pathogen interactions at early stages of
infection by the obligate biotrophic fungus
Podosphaera pannosa , which causes powdery mildew , and the hemibiotrophic fungus
Diplocarpon rosae , which causes black
spot , we analyzed changes in the leaf transcriptome after the inoculation of detached rose leaves with each pathogen . -
pubmed
This report describes the surgical management of a male
patient with
early - stage lung cancer who underwent thoracoscopic completion right lower lobectomy after previously undergoing sublobar resection for multifocal ground glass nodules of the lung . -
pubmed
On 1 - year follow - up ,
patient weight loss was 14 lb . -
pubmed
We report the case of a 4 - year - old boy with
intestinal obstruction due to
Ascaris lumbricoides infestation and discuss its public health significance . -
pubmed
The study reviewed the clinicopathological features and outcomes of
patients who developed
t - MN . -
pubmed
METHODS : Retrospective analysis of all
patients diagnosed with
t - MN by 2016 WHO classification , from a cohort of 521
patients who received PRRT / PRCRT over a 12 - year period . -
pubmed
RESULTS : Twenty - five of 521 ( 4.8 % )
patients were diagnosed with
t - MN , including six
acute myeloid leukaemia (
AML ) and 19
myelodysplastic syndrome (
MDS ) . -
pubmed
Twenty - two of 25 ( 88 % )
patients had grade 1 - 2 pancreatic or small bowel
NEN with moderate
metastatic liver burden . -
pubmed
Azacitidine therapy was utilised in ten eligible
patients , while four received induction chemotherapy for
AML . -
pubmed
Sexual transmission by African genotype ZIKVs has not been assessed in laboratory animal models , due to rapid and high mortality rates of
immunodeficient mice following inoculation . -
pubmed
The African genotype and chimeric
ZIKV elicited greater pathogenic effects in the male reproductive tract and generated higher
viremias . -
pubmed
The extracts revealed also able to inhibit fungal and bacterial species involved in
ulcerative colitis , including
Candida albicans ,
Candida tropicalis ,
Staphylococcus aureus , and
Staphylococcus thyphimurium . -
pubmed
Finally , we also showed the antiproliferative effects exerted by the EA extracts on
human colon cancer HCT116 cell line . -
pubmed
The goal of enhanced recovery is to improve
patient outcome by improving organ function and decreasing
postoperative complications , and therefore decreasing length of hospital stay . -
pubmed
Conclusion A model that includes pretreatment
fluorine 18 - fluorodeoxyglucose PET texture features from the primary
tumor ,
tumor penumbra , and bone marrow predicts
disease - free survival of
patients with
non - small cell lung cancer more accurately than clinical features alone . -
pubmed
OCTA has become an important tool nowadays in the diagnosis and follow - up of
patients with age - related
macular degeneration ,
inherited chorioretinal diseases ,
diabetic retinopathy ,
retinal vascular occlusive diseases and
optic nerve disorders . -
pubmed
This mini - review describes the use of OCTA in
patients with
NIPU and summarizes some practical points in several uveitic entities . -
pubmed
Untreated
patients in need of systemic therapy with symptomatic and progressive
iNHLs including follicular ( FL ) and
marginal zone lymphoma (
MZL ) , mucosa - associated lymphoid tissue ( MALT ) , small lymphocytic (
SLL ) , and lymphoplasmacytic (
LPL )
lymphoma were eligible . -
pubmed
Two - hundred and fifty
patients [ FL 42 % ,
MZL / MALT 38 % ,
LPL/
Waldenstrom Macroglobulinaemia (
WM ) 11 % ,
SLL 9 % ] were enrolled and randomized ( R - CHOP : 127 , R - CVP : 123 ) . -
pubmed
Grade III / IV adverse events ( 65 vs. 22 ) occurred in 40 ( 33 1 % ) and 18 ( 15 3 % )
patients , P = 0 001 ;
neutropenia in 16 ( 11 6 % ) and 4 ( 3 4 % )
patients , P = 0 017 ;
infection in 14 ( 10 7 % ) and 3 ( 2 5 % )
patients , ; P = 0 011 ; and a second
neoplasm in three versus seven
patients . -
pubmed
This multicentre randomized study with > five - year follow - up shows similar outcome in
patients with indolent
lymphoma in need of systemic therapy treated with
R - CVP or R - CHOP immunochemotherapy and
rituximab maintenance in both arms . -
pubmed
INTRODUCTION : The most suitable treatment in most early - stage
lung cancer patients is surgical resection . -
pubmed
METHODS : A prospective analysis study with 3,307
patients operated for
bronchopulmonary carcinoma in 24 hospitals . -
pubmed
After initial radiographs , ultrasound ( US ) is often the next modality utilized to evaluate
patients with suspected
soft tissue infections given its low cost , availability , portability , and potential for real - time guidance of fluid aspiration . -
pubmed
METHODS : A retrospective analysis was performed to identify
patients with phyllodes
tumors who underwent surgery between 2002 and 2014 using a regional pathology database . -
pubmed
Here , we demonstrate that
rheumatoid arthritis (
RA ) patients and
arthritic mice have a reduction in microbial - derived
short - chain fatty acids (
SCFAs ) compared to healthy controls and that in
mice , supplementation with the
SCFA butyrate reduces
arthritis severity . -
pubmed
Efficacy and safety of immune checkpoint blockade in self - identified black
patients with advanced
non - small cell lung cancer . -
pubmed
BACKGROUND : To the authors ' knowledge , race - based differences in efficacy for the treatment of
patients with advanced
non - small cell lung cancer (
NSCLC ) have not been studied to date due to the underrepresentation of patients of minority backgrounds in pivotal trials . -
pubmed
METHODS : The authors retrospectively analyzed the clinical outcomes of
patients with advanced
NSCLC who were treated with single - agent immune checkpoint blockade ( ICB ) between 2013 and July 2018 at Winship Cancer Institute of Emory University in Atlanta , Georgia . -
pubmed
The
malaria parasite ,
Plasmodium falciparum , was introduced into Hispaniola and other regions of the Americas through the slave trade spanning the 16th through the 19th centuries . -
pubmed
Multimodality imaging in a
patient with
hydatid disease of the pelvic bone . -
pubmed
11
children ( 3.2 % ) required intensive care admission for altered mental status /
status epilepticus ( 3 ) ,
sepsis ( 2 ) and
ARDS ( 6 ) . -
pubmed
A percentage of
patients with
PCMs present with
trigeminal pain . -
pubmed
We present four
patients with small
PCMs presenting with
Trigeminal neuralgia (
TN ) that were treated with radiosurgery and continued to have debilitating
trigeminal pain afterwards . -
pubmed
METHODS :
Patients with
petroclival meningiomas presenting with
trigeminal pain and having persistent
pain after treatment with radiosurgery were included in our review . -
pubmed
Those
patients were treated with microsurgical resection of their
tumor to help control their persistent
pain . -
pubmed
The primary aim of the review was to assess the
patients ' Barrow Neurological Institute ( BNI )
trigeminal neuralgia scores following microsurgical resection . -
pubmed
Twenty - six
patients with
cervical spondylosis and
radiculomyelopathy were treated surgically . -
pubmed
Mediterranean fruit flies :
sterility and sexual competitiveness in the laboratory after treatment with gamma irradiation in air ,
carbon dioxide ,
helium ,
nitrogen or partial vacuum . -
pubmed
Four adult female
patients with
moyamoya vessels are described . -
pubmed
Hypertension and
hyperlipidaemia were discovered in three
patients . -
pubmed
This paper reports on 25
patients with
MVP in a family practice setting and compares this experience to recent literature on this problem . -
pubmed
Thirteeen
patients with the characteristic
signs and symptoms of the
nevoid basal cell carcinoma syndrome (
NBS ) are presented . -
pubmed
The
jaw cysts removed from the
patients with
NBS were clinically , radiologically , and histopathologically typical
keratocysts with a high occurrence of epithelial islands and/or microcyts in the connective tissue of the capsule . -
pubmed
The significantly higher occurrence of proliferative epithelial remnants in the connective tissue of the
cyst wall may be an explanation of the high
recurrence rate seen in
patients with
NBS and of the
recurrence of some
solitary keratocysts in
patients without any signs or symptoms of
NBS . -
pubmed
In a follow - up period of 2 years , 85 % of the
patients with
NBS showed recurrence . -
pubmed
One - third of these
patients did not show any
recurrence at the 1 - year follow - up . -
pubmed
Therefore , a follow - up period of 2 years or more is mandatory in the care of
patients with the nevoid
basal cell carcinoma syndrome . -
pubmed
In vitro and in vivo studies on the mechanism of experimental
autoimmune thyroiditis in
guinea pigs . -
pubmed
Letter : Serological evidence for
infection of
sheep with
Leptospira interrogans serotype hardjo . -
pubmed
In the present investigation 100
psoriatic patients were examined for the presence of
oral lesions . -
pubmed
Tracheobronchial aspirates were obtained from 27 normal
horses and from 57
horses with
respiratory disease . -
pubmed
Eosinophils were rarely found , even from
horses with histories suggestive of
allergic respiratory disease . -
pubmed
Aspirates from
horses with
epistaxis frequently had macrophages with intracytoplasmic green globules (
hemosiderin ) . -
pubmed
Four
horses with no clinical signs of
lung disease and lungs that were unremarkable on percussion and normal on auscultation had adpirates suggestive of
inflammation ; histologic examination confirmed
bronchiolitis . -
pubmed
Coumarin is an investigational new drug that has produced objective
tumor regression in some
patients with
metastatic renal cell carcinoma and
malignant melanoma . -
pubmed
Coumarin has shown activity against
prostatic carcinoma in the Dunning R-3327
rat prostatic adenocarcinoma model . -
pubmed
Coumarin is a relatively nontoxic drug that may warrant further trials in a subset of
patients with
prostatic carcinoma . -
pubmed
Eighteen
patients with
necrotizing fasciitis of the extremities were reviewed . -
pubmed
The subtle size differences between the large aggregating PGs isolated from
rat chondrosarcoma ,
bovine nasal septal cartilage , and adult
bovine articular cartilage ( which consists of two subpopulations ) can be distinguished by their migration on these large pore gels . -
pubmed
Nine consecutive
patients were studied with a presumable diagnosis of
pulmonary aspergilloma . -
pubmed
Hypothermia and
infection in elderly
patients admitted to hospital . -
pubmed
Twenty - five consecutive elderly
patients with
hypothermia were studied . -
pubmed
An autopsy case of a 70 - year - old
woman with
sarcoidosis followed up for 16 years is reported . -
pubmed
Electrical carotid
sinus nerve stimulation was applied in three normotensive
anginal patients and one
hypertensive patient during upright tilting . -
pubmed
Different patterns of glycolipid antigens are expressed following differentiation of
TERA-2 human embryonal carcinoma cells induced by
retinoic acid ,
hexamethylene bisacetamide (
HMBA ) or
bromodeoxyuridine (
BUdR ) . -
pubmed
Haemodynamic and hormonal effects of
cilazapril in comparison with
propranolol in healthy
subjects and in
hypertensive patients . -
pubmed
Seventeen
hypertensive patients received after a 2 week placebo period in random order
cilazapril ( 2.5 mg day-1 ) or
propranolol ( 120 mg day-1 ) for 3 weeks . -
pubmed
The fimbriae of 50
strains of
serotype Gallinarum and 35
strains of serotype Pullorum of the genus Salmonella were compared with the type-1 fimbriae of
serotype Typhimurium strains by immune electron microscopy and dot blot hybridization tests with gene probes for type-1 fimbriation in Typhimurium . -
pubmed
A
pancreatic injury may evolve over time so that repetitive clinical diagnostic studies may be required to evaluate the condition of these
patients . -
pubmed
In seven conscious
dogs , endocardial ST - segment changes within the central ischemic area at 2 min after
coronary occlusion were compared with the amount of reactive
hyperemia and collateral blood flow . -
pubmed
We have treated 29
patients with
UM ( 9 treated continuously and 20 treated intermittently ): II with
PV , 16 with
ET , and 2 with
myelofibrosis (
MF ) . -
pubmed
Three
patients developed
AL , two after continuous therapy . -
pubmed
These two
patients with
PV had received the fourth highest and highest total dose of
UM , and their duration of treatment was the third and fourth longest among the nine
patients treated continuously , respectively . -
pubmed
One out of 20
patients treated intermittently with UM developed
AL . -
pubmed
This
patient ( 3 ) with
ET had received the highest total dose of
UM , and her duration of treatment was the longest among the 20
patients treated intermittently . -
pubmed
A comparison of the efficacy of high dose and normal dose
budesonide in
prednisone dependent
patients with
chronic obstructive lung disease (
COLD ) . -
pubmed
Mononuclear as well as polymorphonuclear cell infiltration was seen predominantly in the pars plana region of the ciliary body of test
animals with
uveitis . -
pubmed
Increasing the concentration of
glucose from 5 to 10 mM in the perfusion fluid did not alter the function in either control or in
diabetic rat hearts . -
pubmed
When the study was repeated on hearts from 6 - week
diabetic animals , cardiac function of
diabetic rats was significantly depressed as compared with controls . -
pubmed
on the acquisition of kindled - amygdaloid
seizures in the
rat was studied . -
pubmed
Further studies with additional fully amygdaloid kindled
rats failed to show significant modification of suprathreshold or threshold elicited
seizures after single 30 - 60 mg / kg i.p . -
pubmed
Despite previous studies which have shown antibodies to GM1
ganglioside to be
convulsive , no anticonvulsant activity was demonstrated in this study with exogenous GM1 ganglioside using a battery of kindled - amygdaloid
seizure tests in the
rat . -
pubmed
Neural tube closure defects occurred in 33 % of the embryos obtained from matings of male
mice heterozygous for a reciprocal chromosome translocation ( T(2;4)1Sn ) with normal female CFLP
mice . -
pubmed
Two definitive chronic inhalation bioassays on
rodents have demonstrated that
formaldehyde produces
nasal cancer in
rats and
mice at 14 ppm and in
rats at 6 ppm , which is within the domain of present permissible
human exposure ( 8 - hr time - weighted average of 3 ppm , a 5 ppm ceiling , and a 10 ppm short - term exposure limit ) . -
pubmed
Comparison with the values of
PBI in healthy
children , in
children with
hypothyroidism during therapy and in children with tall stature ] . -
pubmed
Potentiation of amygdaloid kindling and
metrazol - induced
seizures by
6 - hydroxydopamine in
rats . -
pubmed
Pseudomonas aeruginosa cervical diskitis with
chondro - osteomyelitis in an intravenous drug abuser . -
pubmed
Studies on the mechanism of cytoplasmic antigen accumulation following
infection with a new variant of
polyoma virus . -
pubmed
Although the simultaneous measurement of multiple peptides in
patients with benign
gastrointestinal disease has yielded information that contributes to our understanding of the complexities of gut neuroendocrine interaction , the pathophysiological role of gut peptides and their clinical relevance need further evaluation . -
pubmed
In 38
hyperlipoproteinemic patients , known to be at risk for early
CVD , fibrinolytic activity was measured before and after stimulation with
DDAVP . -
pubmed
Fibrinolytic activity and response to
DDAVP were lowest in those
patients with
hypertriglyceridemia who also had a tendency to develop
hyperchylomicronemia . -
pubmed
Pattern - reversal retinal potentials ( PRRPs ) are electrical signals generated within the
human retina , possibly by the retinal
ganglion cells , when a phase - alternating checkerboard pattern ( or grating ) is viewed . -
pubmed
At the time of diagnosis by renal biopsy two
patients had severe
chronic renal failure . -
pubmed
STUDY DESIGN :
Patients treated with a transpedicular anterior and posterior convex hemiepiphysiodesis and hemiarthrodesis for progressive
congenital scoliosis were followed to evaluate this treatment . -
pubmed
METHODS : Nineteen curves were fused in 16
patients who had a variety of
congenital anomalies . -
pubmed
CONCLUSIONS : This procedure appears to be most effective in arresting growth in the young
patient who has an isolated
hemivertebrae and no excessive
kyphosis . -
pubmed
The effect of nasal CPAP on
nocturnal reflux in
patients with aperistaltic esophagus . -
pubmed
It has been shown that nasal continuous positive airway pressure ( nasal CPAP ) significantly reduces nocturnal reflux both in
patients with
sleep apnea and in
patients without
sleep apnea but consistent abnormal
nocturnal reflux . -
pubmed
Seven
patients with
scleroderma esophagus and six
patients treated for
achalasia were tested over a 48 - h period . -
pubmed
The percentage of time the pH & lt ; 4.0 , the number of reflux events & gt ; 5 min , and the length of the longest reflux event were all significantly reduced in the
patients with
achalasia ( p & lt ; 0.03 ) , but not in the
scleroderma group ( p & gt ; 0.20 ) . -
pubmed
These results suggest that a residual resting LES pressure greater than that demonstrated by
patients with
scleroderma ( & gt ; 10 mm Hg ) may be necessary for nasal CPAP to affect
nocturnal reflux . -
pubmed
Zygomycosis caused by
Conidiobolus coronatus in a
llama (
Lama glama ) . -
pubmed
RESULTS : The mean duration of
infection was 3.0 years ( SD 1.9 years ) , and between four and ten courses of antibiotics had been prescribed for six of the 12
patients . -
pubmed
Clinical improvement was dramatic in most lesions , and four
patients healed completely without
recurrence after a total 7 - 10 g of
ceftriaxone . -
pubmed
Increased risk of
Pneumocystis carinii pneumonia in
patients with
Wegener ' s granulomatosis . -
pubmed
During a 10 - month period , we observed 6 cases of
Pneumocystis carinii pneumonia (
PCP ) in 23
patients with biopsy - proven
WG and
renal involvement . -
pubmed
Renal function was significantly impaired (
creatininemia = 493.5 vs 195.4 micromol / l ; p = 0.03 ) in the 6
patients presenting
PCP vs those without . -
pubmed
For these
patients , this
opportunistic infection must remain highly suspect in order to reach a diagnosis earlier and rapidly initiate treatment . -
pubmed
The high levels of
LTB4 measured in the bronchoalveolar lavages and pulmonary tissues from nonimmune animals infected with live bacteria implicate
LTB4 as an important amplifier of the inflammatory response during acute
pulmonary infections with mucoid
P. - pubmed
METHODS : Pregnancy outcome was studied in 311
women with class B - RF
diabetes from two institutions . -
pubmed
Using 104
women without
chronic hypertension followed at the University of California , San Francisco , we constructed a receiver - operating characteristic curve relating 24 - hour urinary
total protein before 20 weeks ' gestation to the subsequent development of
preeclampsia . -
pubmed
From the curve , a predictive cutoff level of
proteinuria was selected and tested in two validation groups not used to construct the curve : 158
women without chronic
hypertension followed at the University of Cincinnati and 49
women with chronic
hypertension from both institutions . -
pubmed
The Wistar fatty
rat is a model of
obese non - insulin - dependent diabetes mellitus . -
pubmed
On the other hand , female fatty
rats develop
hyperglycemia only when they are given
sucrose for several weeks . -
pubmed
The paper presents a
patient with
acute pancreatitis (
AP ) after partial gastrectomy by means of Billroth mode . -
pubmed
METHODS : We analyzed the clinical course of 271
hypertensive patients delivered at a tertiary center . -
pubmed
An 11 - month - old
boy with
Downs Syndrome and
obstructive sleep apnoea presented for tonsillectomy . -
pubmed
Seven groups ( 2596 subjects ) were vaccinated with a
human live
anthrax vaccine (
HLAV ) by three different routes ( scarification , subcutaneous and aerosol ) . -
pubmed
Rats pituitary - grafted at the 30th day showed a greater
hyperprolactinemia than
rats grafted at the 5th or 60th day . -
pubmed
The case is described of a 58 year old
man with systemic
Whipple ' s disease with
pericardial and pleural effusions and severe
pulmonary hypertension . -
pubmed
The aim of this work was to evaluate in an immunosuppressed
rat cryptosporidiosis model a new method that combines vacuum and low - temperature
hydrogen peroxide gas plasma for sterilization of endoscopic material contaminated by
Cryptosporidium parvum . -
pubmed
Septic
thrombus formation of both the main portal vein and its intrahepatic branches were observed on CT in a
patient with peripancreatic
abscess . -
pubmed
The management and clinical course of
patients with
myasthenia gravis admitted to a neurological intensive therapy unit ( ITU ) for thymectomy over a 66 month period were reviewed . -
pubmed
Plasma exchange was required for two
patients ( 3.8 % ) due to persistent severe
myasthenic weakness . -
pubmed
Thymectomy for
myasthenia gravis is followed by sustained clinical improvement in the majority of
patients . -
pubmed
Tamoxifen and
toremifene , both used to treat advanced
breast cancer , also have beneficial effects on bone mineral density and serum lipids in postmenopausal
women . -
pubmed
Tamoxifen was recently shown to decrease the risk of invasive
breast cancer in
women at high risk . -
pubmed
Raloxifene , used for prevention of
postmenopausal osteoporosis and
fragility fractures , also has favourable effects on bone mineral density , serum lipids and the incidence of invasive
breast cancer in postmenopausal
women but does not stimulate the endometrium . -
pubmed
Cortical dysgenesis arising from
neuronal migration disorders is closely associated with intractable
epilepsy in
humans . -
pubmed
These results suggest that the excitability of the CA1 region in
rats with
hippocampal dysplasia is greater than in control
animals . -
pubmed
Prospective genotyping of
schizophrenic patients for the many genes at the level of the drug target , drug metabolism , and disease pathways will contribute to individualized therapy matching the
patient 's unique genetic make - up with an optimally effective drug . -
pubmed
IAPAC proposes rationing
HIV drugs in the U.S. International Association of Physicians in
AIDS Care . -
pubmed
Risk assessment in
patients with
acute myocardial infarction treated with thrombolytic therapy . -
pubmed
We investigated consecutive
patients with
AMI treated with thrombolysis to further clarify this issue . -
pubmed
RESULTS : A total of 6
patients died , seven had a nonfatal
reinfarction , and 23 were revascularized . -
pubmed
Patients suffering either
death or nonfatal
reinfarction had a clinical risk assessment score 2 points higher ( 8.8 vs. 6.7 , P = 0.05 ) than the group without such events . -
pubmed
via echocardiography ) contribute with prognostic information in thrombolysed
MI -
patients . -
pubmed
METHODS : Vitreous fluid was taken from
patients with
PDR ( ET-1 , n = 12 ; NO , n = 12 ) and from
patients with
macular holes as controls ( ET-1 , n = 10 ;
NO , n = 10 ) at vitreous surgery . -
pubmed
There was a significant difference between
patients with
PDR and controls ( P = 0.009 , Mann - Whitney ) . -
pubmed
Nitrate (
NO3 ) was 49.8 + /- 5.0 micromol / L in
patients with
PDR and 24.2 + /- 2.8 micromol / L in
patients with macula hole ; it was also significantly elevated in
patients with
PDR ( P = 0.004 , Mann - Whitney ) , whereas
nitrite (
NO2 ) was not detected in this study . -
pubmed
When exponentially growing cells , both
mouse fibroblasts and
human cancer cell lines , were incubated with
purvalanol A for prolonged periods of time ( 24 hr ) , a lasting inhibition of cell proliferation as well as cell
death were observed . -
pubmed
Molecular and morphological studies on the
Anopheles minimus group of mosquitoes in southern China : taxonomic review , distribution and
malaria vector status . -
pubmed
Malignant rhabdoid tumor of the clitoris in an elderly
patient : report of a case . -
pubmed
We report a case of
malignant rhabdoid tumor of the clitoris occurring in an elderly
patient . -
pubmed
OBJECTIVE : To compare the predictive value of conventional two - dimensional ultrasound measurement of cervical length and three - dimensional multiplanar volume assessment of the cervix for delivery at & lt ; 37 weeks of gestation among
patients with
preterm labor . -
pubmed
MATERIALS AND METHODS : This preliminary prospective study was conducted in 28
patients hospitalized for
preterm labor between 24(+0 ) and 33(+6 ) weeks of gestation , defined by regular and painful uterine contractions ( at least two per 10 min ) , intact membranes and a cervical length of & lt ; or = 26 mm measured by two - dimensional transvaginal ultrasonography at admission with a Voluson 530 ( Kretz , France ) machine using a 7.5 - MHz transvaginal transducer . -
pubmed
Convulsive threshold values to parenterally injected
pentamethylenetetrazole in
epileptic monkeys . -
pubmed
[ Isoplasm therapy of acute
dehydration in
children ] . -
pubmed
Comparative studies on adrenal cortical function and
cortisol metabolism in healthy adults and in
patients with
shock due to
infection . -
pubmed
A study of the
anemia occurring in the
tumor - bearing
mice of the C3H
strain . -
pubmed
The aim of this case - control study was to investigate the relationship between trace elements , immune parameters , and
human cancer , taking into account some personality traits , such as
anxiety , implicated in the modulation of both immune responses and pathology . -
pubmed
Thirty
patients affected by the most frequent
cancer types were recruited at the onset of disease together with 30 healthy controls . -
pubmed
The only differences found between trace element levels in cases and controls were significantly higher erythrocyte
Zn in
cancer patients and higher plasma
Cu levels in male patients . -
pubmed
Interestingly , in
patients only ,
GSH - Px in plasma was positively related to trait
anxiety scores ( p & lt ; 0.02 ) and
Cu to state
anxiety scores ( p & lt ; 0.05 ) . -
pubmed
Improved glycemic control induces regression of left ventricular mass in
patients with
type 1 diabetes mellitus . -
pubmed
We sought to determine whether improved glycemic control in
patients with
type 1 diabetes mellitus will induce reversal of those abnormalities . -
pubmed
METHODS : We prospectively studied 19
patients ( mean age 40+/-9 years ) with longstanding
type 1 diabetes mellitus ( 28+/-4 years ) , who participated in a program of stringent glycemic control . -
pubmed
CONCLUSIONS : Improved glycemic control in
patients with
type 1 diabetes mellitus is associated with regression of septal thickness and left ventricular mass without significant effect on systolic or diastolic function , in the absence of significant alterations in ambulatory 24 - h blood pressures . -
pubmed
The authors report two cases of
patients presenting with complex
voiding disorders treated successfully by bilateral neuromodulation . -
pubmed
The incidence of
bacteremias due to
MRSA and
Pseudomonas aeruginosa has remained unchanged ( P & lt;.20 ) ; however , that due to enteric gram - negative bacteria , particularly
Klebsiella pneumoniae has increased ( P = .02 ) . -
pubmed
Prognostic factors for survival of
patients with
glioblastoma : recursive partitioning analysis . -
pubmed
Survival for
patients with
glioblastoma multiforme is short , and current treatments provide limited benefit . -
pubmed
In this retrospective study of 832
glioblastoma multiforme patients enrolled into prospective clinical trials at the time of initial diagnosis , we evaluated several potential prognostic markers for survival to establish risk groups . -
pubmed
The 2 lower risk groups included
patients under the age of 40 , the lowest risk group being young
patients with
tumor in the frontal lobe only . -
pubmed
Eighty
patients with acute
right hemisphere stroke and 81 controls performed the CLBT that consists of two subtests , the Letter - line and Star - line Bisection tasks . -
pubmed
This total score detected 55 ( 68.8 % )
patients with
neglect . -
pubmed
Within this group , the Letter - line and Star - line tasks diagnosed
neglect in 50 and 48
patients , respectively , resulting in the highest sensitivities ( 90.9 , 87.3 % ) of the six tests . -
pubmed
These data suggested that it is possible to apply them to hemodialyzers , oxygenators and percutaneous
glucose sensors to keep
diabetic patients easier . -
pubmed
INTERPRETATION : High bone mineral content at operation correlates significantly with
periprosthetic bone loss after five years in younger
patients with cementless custom femoral implant . -
pubmed
BACKGROUND : Cardiac resynchronization reduces symptoms and improves left ventricular function in many
patients with
heart failure due to
left ventricular systolic dysfunction and
cardiac dyssynchrony . -
pubmed
CONCLUSIONS : In
patients with
heart failure and
cardiac dyssynchrony , cardiac resynchronization improves symptoms and the quality of life and reduces complications and the risk of
death . -
pubmed
The recurrent laryngeal nerves were examined by electron microscopy in five control , four subclinical and four clinical laryngeal
hemiplegic horses . -
pubmed
This
syndrome , first described by Widal in 1922 , is very frequent : it affects nearly 15 % of asthmatic
patients and is usually associated with severe and sometimes fatal
asthma . -
pubmed
An immunopharmacological study of basophil activation ( detected by flow cytometry ) ,
sulfidoleukotriene production in the presence of NSAIDs in vitro , and other related studies reviewed here have revealed that : a ) basophils from
patients with the
Widal syndrome are hyperactivated in a non specific manner , probably related to
chronic inflammation in the skin or airways ; b ) these hyperactive basophils produce increased amounts of
sulfidoleukotrienes but decreased amounts of
PGE2 when exposed to NSAIDs in vitro . -
pubmed
Rats ' presses on one lever canceled
shocks programmed after variable cycles , while presses on a second lever occasionally produced a 2 - min timout during which the
shock - delection schedule was suspended and its correlated stimuli removed . -
pubmed
Analyses based on the generalized matching law suggest that the reduction in the response requirement correlated with termination of the avoidance schedule was a more important factor in the reinforcing effectiveness of timeout than was
shock - frequency reduction , at least in 2 of 3
rats . -
pubmed
Ventricular fibrillation during no - flow global
ischemia in isolated
rabbit hearts . -
pubmed
INTRODUCTION : The dominant frequency ( DF ) during
ventricular fibrillation (
VF ) in Langendorff - perfused
guinea pig hearts is higher in left ventricle ( LV ) than in right ventricle ( RV ) . -
pubmed
METHODS AND RESULTS : By using a two - camera optical mapping system , epicardial activation patterns of VF were studied in 12 isolated
rabbit hearts during baseline , no - flow global
ischemia , and reperfusion . -
pubmed
A bimodal extended - release formulation of
d - methylphenidate (
d - MPH ) has been developed to enable fast onset of action and once - daily administration in
patients with
attention deficit hyperactivity disorder . -
pubmed
Two hundred twenty thousand
children each year acquire
folic acid - preventable
spina bifida because many governments , including all in Europe , have yet to implement mandatory
folic acid fortification . -
pubmed
BACKGROUND AND PURPOSE : Priorities in the care of
stroke patients are often intuitive . -
pubmed
METHODS : The authors retrospectively reviewed the charts of 44
patients who presented to Louisiana State University Health Sciences Center with
pelvic plexus tumors . -
pubmed
Clinical utility of breast magnetic resonance imaging in
patients presenting with primary
breast cancer . -
pubmed
Since magnetic resonance imaging ( MRI ) of the breast has been shown to be sensitive in identifying the extent of the primary
tumor and other foci of
cancer , we examined its clinical utility in the surgical management of
breast cancer patients . -
pubmed
From January 2004 to April 2007 , 117
patients with newly diagnosed
breast cancer underwent bilateral MRI prior to definitive surgical management . -
pubmed
Six
patients ( 5.1 % ) had a larger area of
tumor than detected by mammography or ultrasound . -
pubmed
Additional foci of
cancer were identified in 17
patients ( 14.5 % ): 12 ( 10.2 % ) in the ipsilateral breast and 5 ( 4.3 % ) in the contralateral breast . -
pubmed
The main objective of this review is to analyze recent advances and current perspectives in the use of antibiotic delivery systems in the treatment of intracellular
infections such as
mycobacterial infections ,
brucellosis ,
salmonellosis ,
listeriosis ,
fungal infections ,
visceral leishmaniasis , and
HIV . -
pubmed
RESULTS : Among 151 out of 1935 infected patients 20 were colonized and infected by
strains of multidrug - resistant
A. - pubmed
In the present study , we investigated a large Pakistani family with 11 affected
individuals having
hereditary congenital nail clubbing as a single invariable clinical feature without any associated
ectodermal , skeletal or systemic imperfection . -
pubmed
Toxicity of
3'3 - ditrifluormethyldiphenyl diselenide administered during intra - uterine development of
rats . -
pubmed
Therefore an earlier diagnosis of
MPM is needed to significantly increase the survival of
patients . -
pubmed
HIV - DNA may be used even in masked primary
infection in newborns whose mothers have received HAART . -
pubmed
The role of surgery in
breast cancer patients with isolated
bone metastases at the time of diagnosis . -
pubmed
BACKGROUND : Surgery for the primary
tumor in
breast cancer patients with synchronous isolated bone metastasis is applied for palliation . -
pubmed
METHODS : Forty - four
patients were diagnosed between the dates June 2004 and January 2007 and these
patients are classified according to the removal of the primary
tumor or not . -
pubmed
Patients and
tumor characteristics , removal of the primary
tumor , and response to systemic therapy are examined as the factors that were affecting overall survival and time to progression of the disease . -
pubmed
CONCLUSION : The response to systemic therapy is the major factor on survival in the
breast cancer patients with isolated
bone metastasis . -
pubmed
Quinone type compound ,
pulsaquinone 1 , isolated from the aqueous
ethanol extract of the roots of
Pulsatilla koreana exhibited antimicrobial activities against an anaerobic non - spore - forming gram - positive bacillus ,
Propionibacterium acnes , which is related with the pathogenesis of the inflamed lesions in a common
skin disease ,
acne vulgaris . -
pubmed
This links
tobacco smoke as a potential contributing and/or exacerbating factor in exposed individuals with
chronic rhinosinusitis . -
pubmed
MATERIALS AND METHODS : We reviewed needle biopsy and radical prostatectomy slides from 61
patients in whom
cancer was present on transition zone directed needle biopsy . -
pubmed
[ Effect of new generation application sorbents on the results of complex treatment in
patients with
diabetic foot syndrome ] . -
pubmed
The work objective is the results of complex treatment improvement in
patients with
diabetic foot syndrome . -
pubmed
The work is based on the results of complex treatment analysis data in 32
patients suffering
diabetes mellitus , complicated by
diabetic foot syndrome . -
pubmed
PATIENTS AND METHODS : Between 1979 and 2008 , 23
infants with
MP underwent laparotomy at our institution . -
pubmed
Eleven of the 23
infants ( 47.8 % ) developed
obstructive jaundice postoperatively . -
pubmed
Of these 11
infants , 4 had
acholic stools . -
pubmed
However , ultrasonography and
HIDA scintigraphy should be performed to differentiate BA in
infants with
MP who show prolonged
jaundice with acholic stools . -
pubmed
METHODS : A retrospective chart review was performed of 34 consecutive
patients over a 5 - year period with
NF of the upper and/or lower extremities that required surgical debridement and reconstruction . -
pubmed
Laboratory challenges using specific - pathogen - free
Pacific herring Clupea pallasii from three distinct populations indicated that stock origin had no effect on susceptibility to
viral hemorrhagic septicemia (
VHS ) . -
pubmed
Immune tolerance induction in
patients with
hemophilia A. -
pubmed
Characteristics of
osteoma of the temporal bone in young
adolescents . -
pubmed
The author conducted a retrospective review of the clinical presentation , management , and complications of temporal
bone osteoma in young
adolescents . -
pubmed
The study population was made up of 9 patients-5
girls and 4
boys , aged 12 to 15 years at presentation ( mean : 13.7)-who had been seen for radiologically and histopathologically proven temporal bone
osteoma at the author 's institution over a 9 - year period . -
pubmed
Of this group , 5
patients had extracanalicular
osteoma ( 3 in the mastoid portion of the temporal bone , 1 in the squamous portion , and 1 in the mastoid antrum ) and 4
patients had
osteoma of the external auditory canal . -
pubmed
All
patients were followed for a minimum of 1 year , and no
recurrences and no complications were observed during that time . -
pubmed
Liver transplantation seems ideal for complete resection of
bile duct cancer , but the high
recurrence rate and decreased
patient survival after liver transplant preclude it from being considered standard treatment . -
pubmed
All
patients were reviewed and examined in 2011 to establish whether the
tumour had recurred . -
pubmed
One
patient had developed a solitary nodular
recurrence 8 years after the initial procedure . -
pubmed
PURPOSE : Both
patients with
cutaneous T - cell lymphoma (
CTCL ) and those with
atopic dermatitis (
AD ) have
pruritus , T(H)2 - biased T cells , and a tendency to have
bacterial infections , suggesting a common pathologic basis for these two diseases . -
pubmed
EXPERIMENTAL DESIGN : Skin biopsies and sera were collected from
patients with
CTCL or
psoriasis and from healthy
volunteers . -
pubmed
Gastric mucosa injury model was established by intragastric perfusion of dehydrated
alcohol ( 1.0 mL /
rat ) . -
pubmed
Causes of
death of 32
patients on device support included
multiple organ failure ( 13 ) ,
pulmonary failure ( 6 ) , and
neurologic injury ( 4 ) . -
pubmed
Daphnane diterpene hirsein B downregulates melanogenesis in
B16 murine melanoma cells by
cAMP pathway inhibition . -
pubmed
Therefore , research laboratories and eye clinics using Cirrus HD - OCT as a diagnostic imaging method , can also benefit from a reliable noncontact pachymeter when counseling
patients with
glaucoma and those undergoing corneal and refractive surgeries . -
pubmed
Autoimmune hemolytic anemia in
patients with
beta - thalassemia major . -
pubmed
Hemolysis is a common feature in
patients with
beta - thalassemia major . -
pubmed
Here , the authors described the clinical features and management of 7
patients with
beta - thalassemia major and
autoimmune hemolytic anemia . -
pubmed
These
patients had
fever ,
cough , and tea - colored urine on admission . -
pubmed
Six of the
patients responded well to the management , but 1
patient developed recurrent
autoimmune hemolytic anemia that required
cyclosporin A treatment . -
pubmed
For risk reduction of
listeriosis and
toxoplasmosis , raw animal foods , soft cheeses and packed fresh salads should be avoided ; fresh fruit ,
vegetables and
salad should be washed well and consumed promptly . -
pubmed
In a descriptive and analytic retrospective study we studied the medical records of 63
patients with
diffuse large B - cell lymphoma hospitalized during the period from 1991 to 2007 . -
pubmed
PEPFAR 's support of
TB /
HIV integration has also included significant investment in health systems , including improved laboratory services and educating and enlarging the workforce . -
pubmed
The scale - up of antiretroviral therapy along with support of programs to increase
HIV counseling and testing and improve linkage and retention in
HIV care may have considerable impact on
TB morbidity and mortality , if used synergistically with
isoniazid preventive therapy , intensified case finding , and
infection control . -
pubmed
Issues to be addressed by future programming include accelerating implementation of
isoniazid preventive therapy , increasing access and ensuring appropriate use of new
TB diagnostics , supporting early initiation of antiretroviral therapy for
HIV - infected
TB patients , and strengthening systems to monitor and evaluate program implementation . -
pubmed
Patients with
AS present a specific set of anesthesia - related challenges , and the parturient with
AS presents particular anesthetic considerations . -
pubmed
We report our experience with a parturient with advanced
AS and offer a novel explanation for the high incidence of epidural failures in this
patient population . -
pubmed
We have determined the preferences of these phages for
Mycobacterium tuberculosis and for other
strains of
Mycobacterium smegmatis , and find there is a correlation between genome type ( cluster , subcluster , singleton ) and host range . -
pubmed
BACKGROUND :
Hepatitis B virus ( HBV ) infection is one of the most prevalent
viral infections in
humans and represents a serious public health problem . -
pubmed
The effects of Sutaehwan - Gami on
menopausal symptoms induced by ovariectomy in
rats . -
pubmed
We report here the use of
milnacipran , a
serotonin and
norepinephrine reuptake inhibitor , to treat
phantom limb pain after amputation of injured or diseased limbs in three
patients . -
pubmed
High versus low
radioiodine activity in
patients with
differentiated thyroid cancer : a meta - analysis . -
pubmed
BACKGROUND : The purpose of the meta - analysis was to estimate the effectiveness and
toxicity of low activity
radioiodine ablation versus high activity in
patients with
differentiated thyroid cancer (
DTC ) . -
pubmed
Salivary dysfunction ,
nausea , and
neck pain were significantly more frequent among
patients with higher dose for ablation . -
pubmed
CONCLUSION : Our meta - analysis provides some evidence from randomized trials that a lower activity of
radioiodine ablation is as effective as higher dose after surgery in
patients with DTC with lower
toxicity . -
pubmed
Ominous odors : olfactory control of instinctive fear and
aggression in
mice . -
pubmed
Cysticercosis in
humans is caused by
Taenia solium larvae infestation . -
pubmed
We present a case of
masseter cysticercosis in a young
woman who presented with painful recurrent
cheek swelling . -
pubmed
Copper overload in
patients with
Wilson ' s disease is caused by impairment to the biliary route for excretion of dietary
copper A combination of
neurological , psychiatric and hepatic symptoms can make the diagnosis of
Wilson ' s disease challenging . -
pubmed
METHODS : Advanced
NSCLC patients with
central airway obstruction were enrolled . -
pubmed
Eight
patients were undergoing additional treatment after resolving
airway obstruction . -
pubmed
The neurological examination in the assessment of
polyneuropathy in mechanically ventilated
patients . -
pubmed
We wanted to see which clinical parameters can be used to identify
patients with
polyneuropathy in the intensive care . -
pubmed
Health care utilization and access to
human immunodeficiency virus (
HIV ) testing and care and treatment services in a rural area with high
HIV prevalence , Nyanza Province , Kenya , 2007 . -
pubmed
We present health and demographic surveillance system data to assess associations with health care utilization and
human immunodeficiency virus (
HIV ) service receipt in a high HIV prevalence area of western Kenya . -
pubmed
It is important to include
hypothyroidism as the differential diagnosis in
patients with
cardiac tamponade and altered level of consciousness especially in winter months . -
pubmed
The majority ( 72%;1480/2,2060 ) of the participants responded that they would get tested if free testing were offered , and 67 % ( 1272/1912 ) of those responded that they would test for
hepatitis B / C in conjunction with
HIV . -
pubmed
Most individuals would elect to be tested for
hepatitis with
HIV , which raises the possibility of integrated testing . -
pubmed
Increased macromolecular damage due to oxidative stress in the neocortex and hippocampus of WNIN / Ob , a novel
rat model of
premature aging . -
pubmed
This
animal model exhibits all traits of
metabolic syndrome and has a remarkably reduced lifespan ( 1.5 years as compared to 3 years in parental WNIN
rats ) , albeit , the factors associated with
premature aging are not well understood . -
pubmed
Our study revealed that the magnitude of oxidative stress and DNA damage in the neocortex and hippocampus of 3 - month - old WNIN / Ob
obese rats is as high as that seen in 15 - month - old parental WNIN control
rats . -
pubmed
From these results , it can be concluded that increased oxidative stress - induced damage of macromolecules , probably due to reduced activity of antioxidant enzymes , is associated with
premature aging in WNIN / Ob
obese rats . -
pubmed
OBJECTIVES : This study aimed at identifying the problem areas in GPs ' patient care during the H1N1 and
EHEC ( enterohemorrhagic
strain of
Escherichia coli ) outbreaks . -
pubmed
The
marrow necrosis ,
adipocyte hypertrophy and proliferation , diminished hematopoiesis , thinner and sparse trabeculae , and increased empty osteocyte lacunae in the femoral head were observed in Group M and Group Con
rabbits . -
pubmed
Synergistic in vitro anti -
tumor effect of
letrozole and
everolimus on
human endometrial carcinoma Ishikawa cells . -
pubmed
OBJECTIVES : To investigate the in vitro effect of the use of combination of
letrozole and
everolimus on the proliferation and apoptosis of
human endometrial carcinoma Ishikawa cells . -
pubmed
Bilateral central
retinal vein occlusion in a
patient with disseminated
metastatic renal cell carcinoma treated with
sorafenib . -
pubmed
PURPOSE : The aim of the article is to report a case of a
patient with disseminated
metastatic renal cell carcinoma on long - term treatment with
sorafenib who had developed bilateral central
retinal vein occlusion over a period of 6 months . -
pubmed
METHODS : A 73 - year - old
man with
decreased visual acuity in the right eye and central
retinal vein occlusion in the left eye 6 months previously . -
pubmed
The
patient had been on long - term treatment with the antiangiogenic drug ,
sorafenib for disseminated
metastatic renal cell carcinoma - a highly vascularized
tumor . -
pubmed
CONCLUSION : The
patient with disseminated
metastatic renal cell carcinoma on long - term
sorafenib treatment should undergo periodic ophthalmologic examinations to exclude any potential vascular complications associated with
cancer (
vein occlusion associated with disseminated
metastatic disease ,
tumor embolus ,
tumor thrombus ) or with treatment ( antiangiogenic drugs ,
steroids ) . -
pubmed
Exploration of skin perfusion in cirrhotic
patients with
septic shock . -
pubmed
BACKGROUND & amp ; AIMS : Skin perfusion alterations are early and strong predictors of
death in
patients with
septic shock . -
pubmed
We aimed at assessing whether the mottling score and tissue
oxygen saturation ( StO2 ) could be used as early predictors of death in cirrhotic
patients with
septic shock . -
pubmed
METHODS : This observational study included cirrhotic
patients with
septic shock . -
pubmed
Data of 75 non - cirrhotic
patients with previously reported
septic shock were used as control . -
pubmed
Monitoring
brain tumor vascular heamodynamic following anti - angiogenic therapy with advanced magnetic resonance imaging in
mice . -
pubmed
Advanced MR imaging methods have an essential role in classification , grading , follow - up and therapeutic management in
patients with
brain tumors . -
pubmed
In this study , we described clinical profile and outcome of six
patients of
PSH admitted in neurocritical care unit . -
pubmed
All
patients admitted at neurology critical unit during 6 - month period from August 2013 to January 2014 were screened for the occurrence of
PSH . -
pubmed
RESULTS :
PSH was observed in 6
patients . -
pubmed
The leading causes were
traumatic brain injury ( two
patients ) ,
stroke ( two
patients ) and
Japanese encephalitis (
JE ) ( one
patient ) and
tuberculous meningitis ( one patient ) . -
pubmed
AltitudeOmics : impaired pulmonary gas exchange efficiency and blunted ventilatory acclimatization in
humans with
patent foramen ovale after 16 days at 5,260 m. A
patent foramen ovale ( PFO ) , present in ~40 % of the general population , is a potential source of right - to - left shunt that can impair pulmonary gas exchange efficiency [ i.e. -
pubmed
IDX184 is a
phosphoramidate prodrug of
2 '- methylguanosine-5 '- monophosphate , developed to treat
patients infected with hepatitis C virus . -
pubmed
Muscular dystrophy (
MD ) is the most common
human genetic disease occurring in approximately 1 in 2500 births . -
pubmed
Alternatively , other genes which cause
human MD have been genetically disrupted in
mice . -
pubmed
This paper aims to assess the time - course severity of the disease in the
mouse models and determine which is best for
MD research . -
pubmed
Fate of bone marrow mesenchymal stromal cells following autologous transplantation in a
rabbit model of
osteonecrosis . -
pubmed
In the present study , i - QDs were used to label
rabbit mesenchymal stromal cells ( MSCs ) that were then transplanted into
rabbits to assess differentiation potential in an
osteonecrosis model . -
pubmed
[ Clinical study on efficacy of nasal surgical expansion as a basic operation in treatment of
patients with
OSAHS ] . -
pubmed
OBJECTIVE : To observe the clinical effect of nasal surgical expansion as basical surgical treatment of
patients with
OSAHS . -
pubmed
METHOD : A total of 320
patients with
OSAHS were retrospectively analyzed . -
pubmed
CONCLUSION : Solving the problem of
nasal airway obstruction is the first step in surgical treatment of
patients with
OSAHS . -
pubmed
Perioperative
VTE occurred in 16 % of
cancer patients and was associated with an advanced FIGO stage , but not MV
TF PCA . -
pubmed
To address this issue , the current study was designed to evaluate the correlation of serum
25 ( OH ) D level and disease activity in
patients with
UC . -
pubmed
METHOD : All consecutively selected
UC outpatients referred to a gastroenterology clinic were enrolled in 2014 . -
pubmed
RESULTS : Fifty
UC patients with mean age of 36.98 ( + - 11.81 ) years were evaluated . -
pubmed
CONCLUSION : Lower serum
25 ( OH ) D level might be associated with higher disease activity in
UC patients with mild - to - moderate activity . -
pubmed
Accordingly , the conventional
animal models for
AML are mostly myeloablated as
leukemia can be induced with short latency and complete penetrance . -
pubmed
Recently , a non - irradiated
AML mouse model has been established ; therefore , normal hematopoietic cells can be investigated during
leukemia development . -
pubmed
Experiments based on the non - irradiated
animal model have monitored the kinetics of leukemic and ( intact ) hematopoietic cells in multiple tissues simultaneously ; and thus a systematic computational model for the multi - tissue hematopoiesis under
leukemia has become possible . -
pubmed
Here , we present the first reported case of the course of pregnancy in a
woman with the systemic form of
Degos disease . -
pubmed
Combined
beta - glucosylceramide and
ambroxol hydrochloride in
patients with
Gaucher related Parkinson disease : From clinical observations to drug development . -
pubmed
RTX patients with at least one episode of
CMV viremia tended to have lower GrB+ B - cells as compared to
patients without
viremic episodes . -
pubmed
Polycystic kidney diseases (
PKDs ) are
genetic disorders that can cause
renal failure and
death in
children and adults . -
pubmed
Case : A 66 year - old
woman who presented with sudden lower
abdominal pain was transferred to our emergency room . -
pubmed
The goal of our current study is to understand the impact of chronological aging on innate immune responses to a secondary , post
viral infection with
Streptococcus pneumoniae , a causative agent of
bacterial pneumonia . -
pubmed
MATERIALS AND METHODS : Fifty consecutive
pectus excavatum patients , 10 to 32 years of age ( mean age 15 + - 4 years ) , underwent routine cardiac magnetic resonance imaging ( CMR ) including standard measures of chest geometry and cardiac size and function . -
pubmed
However , there was significant decrease in mid - cavity circumferential
strain magnitude in pectus
patients compared with controls ( -11.31 + - 2.79 versus -16.19 + - 2.86 ; p & lt ; 0.001 ) . -
pubmed
PE patients had a significantly higher basal circumferential
strain ( -13.66 + - 3.09 % versus -9.76 + - 1.79 ; p & lt ; 0.001 ) as well as apical circumferential
strain ( -20.73 + - 3.45 % versus -12.07 + - 3.38 ) than control group . -
pubmed
CONCLUSION : Mid - cavity circumferential
strain but not longitudinal
strain is reduced in
pectus excavatum patients . -
pubmed
CONCLUSIONS :
Propamidin - isethionate as
diamidine and
chlorhexidin as
biguanide may be used clinically to reduce
cytotoxicity of antiamoebic treatment on
human corneal cells . -
pubmed
Therefore , in spite of lower
cytotoxicity , the inhibitory effect on proliferation and migration indicates that extended use of
propamidin - isethionate should be avoided in
patients . -
pubmed
BACKGROUND :
Cysticercosis (
CC ) is a
tissue infection caused by the larval
cysts of the pork tapeworm
Taenia solium . -
pubmed
In Brazil ,
visceral leishmaniasis is caused by the protozoan
Leishmania infantum , primarily transmitted by
Lutzomyia longipalpis and with the
dog as its main urban reservoir . -
pubmed
METHODS : Thirty - two Japanese healthy adult
rabbits were randomly divided into four groups with 8
rabbits in each group : normal control group ( NC group ) ,
diabetes mellitus group (
DM group ) ,
diabetes mellitus +
pioglitazone 4 mgxkg-1xd-1 and 8 mgxkg-1xd-1 groups ( DM+
PGZ 4 mg and 8 mg groups ) . -
pubmed
The use of these medications is rapidly increasing in elderly
patients with , and without ,
dementia . -
pubmed
Adjuvant
bevacizumab for
melanoma patients at high risk of
recurrence : survival analysis of the AVAST - M trial . -
pubmed
We evaluated the role of adjuvant
bevacizumab in
melanoma patients at high risk of
recurrence . -
pubmed
Patients and methods :
Patients with resected AJCC stage IIB , IIC and III cutaneous
melanoma were randomised to receive either adjuvant
bevacizumab ( 7.5 mg / kg i.v . -
pubmed
With 6.4 - year median follow - up , 515 ( 38 % )
patients had died [ 254 ( 38 % )
bevacizumab ; 261 ( 39 % ) observation ] ; 707 ( 53 % )
patients had
disease recurrence [ 336 ( 50 % )
bevacizumab , 371 ( 55 % ) observation ] . -
pubmed
Two
patients ( 28.5 % ) had
acute kidney injury . -
pubmed
Of the 264
children included in the statistical analysis , four were diagnosed with
ASD , and four were diagnosed with
ODP . -
pubmed
New onset
psoriasis in a
patient with
chronic inflammatory demyelinating polyneuropathy treated with Rituximab . -
pubmed
A fungus was recovered on
potato dextrose agar ( PDA , pH nature ) from the margin of necrotic leaf
spots . -
pubmed
The development of accelerated methods of detection and differentiation of the virulent properties of pathogenic bacteria will allow scientifically to substantiate and develop a set of measures aimed at preventing
animal diseases and obtaining safe livestock products to prevent
human diseases . -
pubmed
Anthracycline - Induced
Cardiotoxicity in
Acute Myeloid Leukemia Patients Who Undergo Allogeneic Hematopoietic Stem Cell Transplantation . -
pubmed
INTRODUCTION : There is paucity of data regarding the
cardiotoxic effects of
anthracycline treatment in the context of
acute myeloid leukemia (
AML )
patients who undergo allogeneic hematopoietic stem cell transplantation ( HSCT ) . -
pubmed
PATIENTS AND METHODS : We reviewed the clinical records and echocardiography examinations of 78
patients with
AML who received induction therapy and underwent HSCT . -
pubmed
Patients who developed
systolic dysfunction had inferior overall survival ( 13 months compared with 27 months ; P = .013 ) . -
pubmed
CONCLUSION : Although even transient reduction in systolic function might compromise survival outcome ,
diastolic dysfunction predicts improved survival in
patients with
AML who undergo HSCT . -
pubmed
Alcohol and
HBV synergistically promote
hepatic steatosis . -
pubmed
Synergy between
hepatitis B virus (
HBV ) and
alcohol in promoting liver cell damage and
disease progression has been reported . -
pubmed
However , the interaction of
HBV and
ethanol in
hepatic steatosis development has not been fully elucidated . -
pubmed
Furthermore , a meta - analysis of the effects of
alcohol and
HBV on
hepatic steatosis in populations was performed . -
pubmed
RESULTS :
Hepatic steatosis was significantly more severe in the
HBV+
EtOH group than in the other groups . -
pubmed
In addition , the meta - analysis showed that
alcohol consumption increased the risk of
hepatic steatosis by 43 % in
HBV - infected patients ( pooled risk ratio ( RR)=1.43 , P<0.01 ) . -
pubmed
CONCLUSIONS :
Alcohol and
HBV synergistically promote high - fat diet - induced
hepatic steatosis in
mice . -
pubmed
RESULTS : Altogether 2 127
patients underwent surgery for morbid
obesity , whereof 1 468 were
women . -
pubmed
Obesity - related sequelae were registered in 1 196
patients before surgery . -
pubmed
A large proportion of the
patients who underwent surgery had
obesity - related
sequalae . -
pubmed
Background : Correcting false cognitions and establishing preventive behaviors in
patients with chronic
low - back pain can improve self - efficacy and self - discovery of these patients against the physical and psychological consequences of
chronic back pain through reinforcing thoughts and constructive behaviors . -
pubmed
Effect of Pars Plana Vitrectomy With or Without
Cataract Surgery in
Patients with
Diabetes : A Systematic Review and Meta - Analysis . -
pubmed
Given the high rate of accelerated
cataract progression after PPV , PPV combined with
cataract surgery appears to be an attractive treatment option for
patients with
diabetes . -
pubmed
In four of these studies , final visual acuity did not vary significantly between
patients undergoing PPV alone and those undergoing PPV combined with
cataract surgery ( combined surgery ) . -
pubmed
In addition ,
patients receiving PPV alone had a lower risk of
neovascular glaucoma ( OR 0.36 ; P & lt ; 0.05 ) ,
iris synechias to anterior capsule ( OR 0.36 ; P & lt ; 0.05 ) , and
iris rubeosis ( OR 0.26 ; P & lt ; 0.05 ) compared with those receiving combined surgery . -
pubmed
Given the high rates of
cataract progression after PPV , combined surgery may be the more appropriate treatment for
patients with
diabetes and coexistent visually significant
cataract . -
pubmed
However , the currently adopted methods of modification of T cells pose a risk of insertional
oncogenesis because
lentiviral and
retroviral vectors integrate the CAR transgene in a semi - random fashion . -
pubmed
Measurement of the somatic cell count ( SCC ) in milk is commonly used to detect
mastitis in lactating dairy
cows . -
pubmed
Many techniques and tools have been developed and adapted to quantify
milk SCC , but few tools have been evaluated in their ability to enumerate somatic cells in non - lactating
bovine mammary secretions . -
pubmed
The objective of these studies was to evaluate methods of somatic cell quantification , originally developed for milk , in their ability to quantify the
SCC in non - lactating
bovine mammary secretions when compared to the gold standard microscopic quantification method . -
pubmed
Development of a standardized approach for quantifying somatic cells in non - lactating dairy animals such as
heifers and
cows , via a rapid automated counter , can allow for the detection of
mastitis in non - lactating dairy animals . -
pubmed
Diagnosis and management of postlaparotomy
wound infection caused by
Mycobacterium fortuitum . -
pubmed
Mycobacterium fortuitum is ubiquitous in nature and can cause a wide variety of lesions in
humans with immunocompromised or antecedent
chronic illness . -
pubmed
Inaccurate point - of - care blood
glucose measurement in a
dog with
secondary erythrocytosis . -
pubmed
KEY FINDINGS : A 1.5 - year - old
dog , previously diagnosed with multiple
congenital cardiac malformations , right - to - left cardiac shunting and
secondary erythrocytosis , presented to a veterinary emergency center minimally responsive and without detectable
pulses . -
pubmed
A pathological cause for
hypoglycemia was not identified and PBGM readings were determined to be erroneously low due to the
dog 's abnormally high HCT . -
pubmed
SIGNIFICANCE : This case demonstrates the limitations of using PBGMs to assess blood
glucose in a
dog with
secondary erythrocytosis . -
pubmed
The report emphasizes the need for judicious use of PBGMs in
critically ill patients and that these glucometers may not be reliable in
patients with abnormal HCT values . -
pubmed
METHODS : A case - control study was performed from April 2011 to February 2016 with pregnant
women with
GDM who needed complementary treatments besides diet and physical exercise . -
pubmed
Removal of
tumor thrombus from the azygos vein in an
esophageal squamous cell carcinoma patient . -
pubmed
Neoadjuvant chemotherapy can decrease the stage in
patients with advanced preoperative
tumor staging , regaining surgical opportunities and significantly prolonging progression - free survival and overall survival . -
pubmed
Herein , we present a case of
esophageal squamous cell carcinoma accompanied by
tumor thrombus in the arch of the azygos vein , and the
patient underwent radical surgery after neoadjuvant chemotherapy . -
pubmed
CASE PRESENTATION : A 63 - year - old
male with
esophageal squamous cell carcinoma was found to have
tumor thrombus formation in the arch of the azygos vein . -
pubmed
In this review , we discuss new advances in pharmacological treatment both in cardiovascular prevention and in
HF management with a special focus on
T2DM patients . -
pubmed
Moreover , SGLT2i demonstrated strong evidence of benefit particularly in
HF management both in
diabetic and non - diabetic
patients . -
pubmed
New therapies , which are on the horizon , promise to further reduce cardiovascular mortality and morbidity in
HF patients irrespective of
diabetic status . -
pubmed
In
women age 45 to 49 years , 61 ( 96.8 % ) had benign follow - up , one ( 1.6 % ) had
atypical hyperplasia , and one ( 1.6 % ) had malignant follow - up . -
pubmed
METHODS : This is a case - series of five
COVID-19 positive
patients who demonstrated severe
hypoxemia , declining respiratory performance , and escalating
oxygen requirements . -
pubmed
Patients met the following criteria : COVID-19 positivity , worsening respiratory performance , severe
hypoxemia ( PaO2 < = 80 ) despite traditional supportive measures , escalating supplemental
oxygen requirements , and D - dimer greater than 1.5 mug / mL. -
pubmed
Patient one was on maximum ventilator support ,
paralytics , and prone positioning without improvement . -
pubmed
Three of these
patients avoided intubation due to COVID-19 - associated
respiratory failure . -
pubmed
Furthermore , the expressions of genes involved in two
heart disease - related pathways were down - regulated at the
death stage of
D. - pubmed
magna after
TCEP exposure for 62 days , suggesting that
TCEP delayed the
death of
D. - pubmed
METHODS : Forty - one
adults with
ID of both sexes , ranging in age from 20 to 60 years old , participated in the study . -
pubmed
An 80 - year - old
woman presented with
abdominal and right lower limb pain . -
pubmed
Fifteen healthy controls ( HC ) , 26 cognitively normal
PD (
PD - CN ) , and 27
PD - MCI subjects participated in this study . -
pubmed
The in vivo gastroprotective effects of that fraction were evaluated using
alcohol - induced
gastric ulcers in
rats . -
pubmed
Therefore , we recommend the use of
Murcott mandarin leaves as a part of a protection strategy for
gastric ulcer . -
pubmed
METHODOLOGY / PRINCIPAL FINDINGS : In this study , extracts of fifteen traditional medicines used for treating various
NTDs in local communities were screened in vitro for efficacy against
schistosomiasis ,
onchocerciasis and
African trypanosomiasis . -
pubmed
Here , we use a combinatorial approach on a characterized
mouse model of hormone induced
male infertility to uncover misregulated pathways . -
pubmed
Results suggest that
infertility is associated with substantial loss of proteomic heterogeneity , which define distinct stages of seminiferous tubuli in healthy
animals . -
pubmed
To achieve the optimum survival rate in
aortic aneurysms , knowledge of natural course , genetic association , and surgical results are needed to be applied with adequate medical treatment and careful selection of
patients for operation . -
pubmed
TAA expands up to 0.3 cm annually in a non - bicuspid aortic valve
patient . -
pubmed
CONCLUSION : In the future , genetic testing may be the gold standard for tackling the geneticheterogeneity of
aneurysms , therefore , identifying at - risk
individuals developing
TAA andAAA earlier . -
pubmed
Solid
tumor models for the assessment of different treatment modalities : II : rapid , intermediate , and slow growing transplantable
rat hepatomas . -
pubmed
A double - blind multicenter trial was carried out in 146
patients with
urinary tract infections in order to compare the combination of
rifampicin and
trimethoprim ( 450 mg plus 120 mg twice daily ) with
rifampicin alone ( 450 mg twice daily ) . -
pubmed
The study reports also four cases of
hepatic vein thrombosis (
Budd - Chiari - Syndrome --
Venoocclusive disease ) and three cases of benign
hepatic tumors (
liver cell adenoma and
focal nodular hyperplasia ) in young
women following 2- to 5 - year treatment with
oral contraceptive steroids . -
pubmed
The rate of excretion of labelled
hycanthone has been determined in bile and urine from three
strains of
rats (
Sprague - Dawley , hooded and Gunn ) , and from
dogs ,
cats ,
rabbits and
monkeys . -
pubmed
Genetic variability within and between outbred Wistar
strains of
rats . -
pubmed
The ventriculograms of
patients with chronic postinfarction
aneurysm of the heart were studied with the use of separate analysis of the contraction indices of the functioning and non - functioning parts of the left ventricular myocardium . -
pubmed
A radiological study of 110
patients with special reference to demonstration of
cerebral plaques . -
pubmed
The brains of 110
patients with
multiple sclerosis (
MS ) were examined by computer tomography ( CT ) with the fine matrix EMI scanner . -
pubmed
No difference was demonstrated between duration of disease or age at onset in
plaque cases ,
atrophy cases and
patients with normal EMI scans . -
pubmed
Congenital malformations were registered in 410
pigs equalizing 1.4 per cent of the
pigs born ( Table I ) . -
pubmed
Patients resistant to the full
hypotensive effects of
sodium nitroprusside , or unable to maintain the level of
hypotension , or requiring more than 3.5 mg per Kg to achieve the required effect for the anticipated time , may accumulate toxic levels of
cyanide in the blood . -
pubmed
Patients with
Leber ' s optic atrophy ,
tobacco amblyopia and possibly those with other
nerve atrophies should not receive
sodium nitroprusside or any other
cyanide precursor . -
pubmed
36
rats and 99
mice survived the terms of appearance of the first
tumors . -
pubmed
In the experiments on
rats sarcomas were found in 9 cases at the site of the injection of the substance . -
pubmed
In one
rat renal adenocarcinoma developed . -
pubmed
Very low values were obtained in
patients suffering from
malignant disease , especially
carcinoma of the prostate . -
pubmed
Ultrasonography was performed in 39
patients and detected
gallstones in 7
patients and sludge in 3 . -
pubmed
Liver biopsies were obtained in 31
patients and
cirrhosis was found in 4 . -
pubmed
The nucleation time ( median : 21 days ) was higher in
patients with
chronic pancreatitis than in
patients with
cholesterol stones ( median : 2 days ) ( P & lt ; 0.001 ) but was not different from nucleation time in
patients either free of stones ( median : 21 days ) or with
pigment stones ( median : 21 days ) . -
pubmed
The
cholesterol saturation index was similar in
patients with
chronic pancreatitis and in controls . -
pubmed
The 2
patients with
chronic pancreatitis who underwent cholecystectomy had
pigment stones . -
pubmed
Reduced attention - related negative potentials in
schizophrenic children . -
pubmed
ERPs were recorded from normal and
schizophrenic children during performance of a reaction time task ( RT ) followed by a complex visual discrimination , the span of apprehension task ( Span ) , sensitive to vulnerability factors in
schizophrenia . -
pubmed
When RT and Span task ERPs are compared ,
schizophrenic children produced a significantly smaller than normal increment in endogenous negative activity . -
pubmed
Angiosarcoma is a well known complication following radiotherapy and
lymphedema , and is likely to be seen more frequently as conservation treatment is used more commonly for
patients with early
breast cancer . -
pubmed
Authors discuss
nephrotoxicity of
aminoglycosides in
patients with
hepatic and biliary disorders . -
pubmed
Various chemicals were tested in
Escherichia coli for the ability to modify the cellular growth rate and to induce the synthesis of heat
shock and stress proteins . -
pubmed
In
patients with previously documented or probable sustained
ventricular tachycardia , it would seem to be necessary to continue ventricular stimulation irrespective to the rate and duration of the induced non - sustained
ventricular tachycardia . -
pubmed
A total of 274
patients ( mean age 67.1 + /- 8.2 years ) with asymptomatic
stenosis of the internal carotid artery greater than 70 % was treated by desobliteration and patchplasty ; 332 reconstructions were performed either uni- or bilaterally . -
pubmed
The author has summed up his experience in the diagnosis and radiation therapy of 6
patients with
breast cancer ( 5 ) and
lung cancer metastases to the vascular coat of the eye . -
pubmed
In 3
patients metastases to the eye developed against a background of
tumor generalization . -
pubmed
Prolonged follow - up identified
relapses in
patients assumed to have been cured . -
pubmed
Clinical utility of liver biopsy in
patients with serum antibodies to the
human immunodeficiency virus . -
pubmed
For example , 70 % of patients with
AIDS , as compared to 25 % of patients with serum antibodies to
HIV but without
AIDS , had diagnostic liver biopsies . -
pubmed
The microbiological etiology of
pneumonia in 34 renal transplant
patients with clinical and X - ray evidence of
pulmonary parenchymal disease was studied . -
pubmed
Laboratory evaluation included histological and cytological methods , cultures for
bacteria , fungus and virus and immunofluorescence techniques for the detection of
Pneumocystis carinii ,
cytomegalovirus (
CMV ) and
legionella . -
pubmed
Pulmonary edema was found in 7
patients ,
bacterial pneumonia in 11
patients ,
P. - pubmed
Bronchoscopy gave correct diagnosis in 13/14
patients with
infectious pulmonary diseases ( 93 % ) . -
pubmed
Favourable clinical effects of the antibiotic needle jet injection were observed in the
patients with acute nonspecific
pulmonary diseases : decreased hospitalization terms and lower total course doses of the antibiotics . -
pubmed
[ Effect of
isoproterenol on regional myocardial
oxygen balance in
dog hearts with
coronary stenosis ] . -
pubmed
Effects of intravenous and intracoronary
isoproterenol on
oxygen balance in the regional myocardium as well as on coronary hemodynamics were investigated in eight
dogs with
coronary stenosis under
droperidol -
fentanyl anesthesia . -
pubmed
Managing
critically ill patients with
esmolol . -
pubmed
Cross sectional osteon diameter ( D ) and Haversian canal diameter ( d ) were measured in undecalcified , unstained sections from the mid - diaphysis of femoral bones from 13
patients with long lasting chronic
pulmonary insufficiency , 10
patients with unilateral
thrombosis of the femoral artery and from sex- and age - matched normal controls . -
pubmed
[ No correlation between suppressor cell function and disease activity in natural history studies of
patients with
systemic lupus erythematosus ] . -
pubmed
In ten
patients with
systemic lupus erythematosus lymphocyte suppressor cell function was repeatedly monitored over a period of nine months . -
pubmed
Increased arterial wall stiffness and thickness in medium - sized arteries in
patients with
insulin - dependent diabetes mellitus . -
pubmed
A
patient with a giant
aneurysm arising from the tonsillomedullary segment of the posterior inferior cerebellar artery ( PICA ) presented with clinical and computed tomography findings suggestive of spontaneous
cerebellar hemorrhage . -
pubmed
The apparent reversal of a
wasting syndrome by nutritional intervention in
Saguinus mystax . -
pubmed
Within 1 year after arrival , the mortality was 60 % and the majority of the
tamarins showed signs similar to "
wasting marmoset syndrome " (
WMS ) . -
pubmed
Under analysis were clinical data and roentgencardiometric parameters in 181
patients with
mitral diseases . -
pubmed
Experiments on
mice with Ehrlich solid
carcinoma showed the dependence of a rise of the antitumor effect of preceding radiation induced by
glucose and
glucose combined with
mexamine on a degree of the blood flow inhibition under the influence of these modifying agents . -
pubmed
These results imply that although
histamine can modulate immune responses in uninfected animals , it is not a major component of the immunoregulatory pathway induced by
infection with
N. - pubmed
Twenty - one
patients with
bladder tumors were treated with
THP instillation into the bladder . -
pubmed
Of 21
patients , 4 showed complete disappearance of the
bladder tumors , while partial response ( 50 %
tumor reduction ) was observed in 6 cases . -
pubmed
The main side effect of
THP instillation was temporary
bladder irritability , which was seen in 57 % of all the
patients . -
pubmed
Ventricular fibrillation was found in 13 of the 20
patients attended by the
cardiac arrest team . -
pubmed
Effect of a synthetic peptide ,
ORG 2766 , on
inpatients with severe
senile dementia . -
pubmed
Fenoprofen calcium 600 mg , four times daily , and
ibuprofen 400 mg , four times daily , were compared in a double - blind crossover study involving the treatment of
soft - tissue rheumatism in fifty
patients . -
pubmed
The effect of chronic administration of
bromocriptine to 20
patients with the
polycystic ovary syndrome (
PCOS ) was studied . -
pubmed
Eleven out of 20
patients ultimately noted a subjective improvement in
hirsutism . -
pubmed
Sex differences in the susceptibility of
rats to
carbon tetrachloride --
alcohol - induced
liver injury . -
pubmed
However , we have found that continuous administration of very low amounts of
amphetamine reliably produces
SB in
rats , and that this behavioral change can be very selective . -
pubmed
We compared SB produced by continuous
amphetamine to SB produced by daily
caffeine ; the latter has been proposed as an
animal model for self - injurious behavior ( SIB ) in the
Lesch - Nyhan syndrome . -
pubmed
The
dopamine antagonist
haloperidol was only marginally effective in controlling
SB produced by daily
caffeine but the
dopamine antagonist
pimozide ( which has a longer duration of action ) prevented SB by
amphetamine pellet
rats . -
pubmed
Continuous release
amphetamine pellets may provide an alternative to the
caffeine model of
SIB in
humans , particularly for the
Lesch - Nyhan syndrome . -
pubmed
A simple transillumination screening test for identifying
patients in whom
mydriasis presents a risk is described . -
pubmed
The case report presented herein describes a forty - six year old
woman with
multiple myeloma and
cutis laxa . -
pubmed
Two of those three had
parapneumonic effusions and the remaining one had a
tuberculous pleurisy with a previous
bacterial empyema . -
pubmed
We have compared the effects of nebulized
adrenaline and a selective
beta 2 agonist (
salbutamol ) on the arterial
oxygen saturation ( SaO2 ) , minute ventilation ( VE ) , forced expiratory volume in 1 s ( FEV1 ) , plasma
potassium and the electrocardiogram ( ECG ) in
patients with chronic stable
asthma . -
pubmed
There was an increased heart rate after both
adrenaline and
salbutamol and
ventricular ectopic beats and a short run of
parasystole were recorded on the ECG in one
patient after
adrenaline and in two
patients after
salbutamol . -
pubmed
We conclude that both
adrenaline and a selective
beta 2 agonist
salbutamol can cause a fall in SaO2 and ventricular ectopy in some
asthmatic patients . -
pubmed
All groups , including control , had
dogs which had a chronic inflammatory response in the epidural space , as represented by
fibrosis ,
foreign body giant cells , and lymphocytes , but no spinal cord pathology . -
pubmed
Plasmids in several
strains of
Deinococcus radiodurans . -
pubmed
A total of 43
patients with advanced , previously untreated
non - small - cell lung cancer (
NSCLC ) were treated with a novel
nitrosourea ,
fotemustine , given at 100 mg / m2 on days 1 and 8 . -
pubmed
A 62 year old
man with
chronic lymphocytic leukaemia presented with
malabsorption , the cause of which could not be found during life . -
pubmed
Physical characterization of plasmid pMQV10 from a
steroid biotransforming
strain of
Micrococcus . -
pubmed
The presence of a single plasmid 8.5 kb in size has been demonstrated in a
cholesterol biotransforming
strain of
Micrococcus . -
pubmed
From 1973 to 1987 , 28
patients seen at our institution sustained isolated
posterior cruciate ligament tears . -
pubmed
Entomological studies on prevalence of adult and immatures of
Aedes aegypti along with associated ecological factors have been conducted in a
dengue endemic area of Jalore , Rajasthan from 1992 to 1993 . -
pubmed
Neutralization of the toxic effects of
scorpion stings by serotherapy is limited due to the various serotypes expressed by these proteins . -
pubmed
HCV viremia levels were not associated with the severity of liver histology , duration of disease or the source of
hepatitis . -
pubmed
Cell cycle gene regulation in reversibly differentiated new
human hepatoma cell lines . -
pubmed
Several novel differentiated cell lines have been derived from a
human hepatocarcinoma named HBG . -
pubmed
Ovine lentivirus (
OvLV ) , a retrovirus , causes
lymphoid interstitial pneumonia (
LIP ) in
sheep . -
pubmed
OBJECTIVE : To better understand the neuropathological correlates of
Tourette ' s syndrome (
TS ) , measures of saccadic eye movement performance were examined among
patients with
TS . -
pubmed
Twenty one
patients with
DSM - IV TS ( mean age 40.6 years ( SD 11.0 ) ; 38 % female ) mainly recruited from UCSD Psychiatry Services , and a community based sample of 21 normal subjects ( mean age 34.6 years ( SD 13.4 ) ; 43 %
women ) participated in this study . -
pubmed
Whereas
patients with
TS generated prosaccades with normal reaction times and amplitudes , their saccade durations were shorter and their mean velocities were higher than in normal subjects . -
pubmed
During a prosaccade gap task ,
patients with
TS exhibited an increased proportion of anticipatory saccades ( RTs<90 ) . -
pubmed
Patients with
TS had fewer correct antisaccade responses than did normal subjects , an effect accounted for by 19 % of the
patients . -
pubmed
Antisaccade reaction times among
patients with
TS were increased during an overlap version of the task . -
pubmed
Nifedipine - induced
gingival hyperplasia : non - surgical management of a
patient . -
pubmed
A clinical report of
nifedipine - induced
gingivitis in a medically compromised
patient is presented . -
pubmed
METHODS : From November 1979 to December 1996 , 50
patients with chronic persistent
empyema were treated by pedicled omentum majus transplanted into the thoracic cavity . -
pubmed
[ The sensitivity of clinical isolates of
Helicobacter pylori and associated microflora to antimicrobial and anti -
ulcer preparations ] . -
pubmed
Combining electrocardiography and
necrosis biomarkers improved detection of acute
myocardial infarction in
patients with
LBBB . -
pubmed
The establishment and maintenance of effective urinary tract drainage for
patients with malignant extrinsic
ureteric obstruction is a formidable challenge for the urologist . -
pubmed
Lake whitefish (
Coregonus clupeaformis ) were fed diets at a ration of 0.5 % of
body weight three times a week containing 0 , 10 , 100 , and 1000 microg
Ni / g ( as
NiSO ( 4 ) ) for 10 , 31 , and 104 days . -
pubmed
OBJECTIVE : The determination of high risk
patients for
sudden death and sustained
ventricular tachycardia after acute
myocardial infarction constitutes the main goal to decrease morbidity and mortality . -
pubmed
METHODS : Thirty - five
patients ( mean age 53 + /- 9 years ) with acute
myocardial infarction who were not given thrombolytic therapy were enrolled . -
pubmed
Decreased
catecholamine - induced cell
death in B lymphocytes from
patients with
rheumatoid arthritis . -
pubmed
MATERIAL : From 1989 trough 1999 , 14 young
patients , 11 male and three female ranging in age between 13 and 24 years were treated for primary
TPPC in our department . -
pubmed
Growth retardation and
skin abnormalities of the
Recql4 - deficient mouse . -
pubmed
[ Experimental study of seven
strains of
lymphocytic choriomeningitis virus of the Armstrong type isolated in
man ] . -
pubmed
Comparison of some physical and chemical properties of eight
strains of
tobacco mosaic virus . -
pubmed
[
Hypervolemia and
hypersalemia in cyanotic
children with
congenital heart defects ] . -
pubmed
Hyperaemia of the deeper cutaneous vessels after irradiation of
human skin with large doses of ultra - violet and visible light . -
pubmed
Candida tropicalis ATCC 20336 can grow on
fatty acids or
alkanes as its sole source of
carbon and energy , but
strains blocked in beta - oxidation convert these substrates to long - chain
alpha , omega - dicarboxylic acids (
diacids ) , compounds of potential commercial value ( Picataggio et al . -
pubmed
This in vitro study investigated the potential of the heat - treated
porcine trabecular bone block as a bone substitute for the treatment of
bone defects or related diseases . -
pubmed
Down syndrome (
DS ) is the
congenital birth defect responsible for the greatest number of
individuals with
mental retardation . -
pubmed
The control of
infectious diseases transmitted from animals to
humans (
zoonoses ) was recently put on a new basis in the European Union when a new Zoonoses Directive entered into force . -
pubmed
Brucellosis ,
campylobacteriosis ,
echinococcosis ,
listeriosis ,
salmonellosis ,
trichinosis , and the respective causative agents ,
tuberculosis due to
Mycobacterium bovis , and verotoxigenic
Escherichia coli must be included in monitoring . -
pubmed
Operative findings and outcomes of microvascular decompression for
trigeminal neuralgia in 35
patients affected by
multiple sclerosis . -
pubmed
Magnetic resonance imaging preoperative identification of suspicious vessels along the cisternal course of the trigeminal nerve in
MS patients raises the question of a possible causative role of vascular compression in
MS patients . -
pubmed
RESULTS : Magnetic resonance imaging revealed the presence of
demyelinating lesions affecting the brainstem trigeminal pathways of the painful side in 26 ( 74 % ) of 35
patients . -
pubmed
During surgery , severe
neurovascular compression at the trigeminal root entry zone was found in 16 ( 46 % ) of 35
patients . -
pubmed
There was no mortality , with a 2.5 % long - term morbidity rate (
facial nerve palsy in one
patient ) . -
pubmed
PARTICIPANTS : 1334
patients consulting their general practices about
low back pain . -
pubmed
Intratumoral injection of IL - secreting syngeneic / allogeneic fibroblasts transfected with DNA from
breast cancer cells prolongs the survival of
mice with intracerebral
breast cancer . -
pubmed
Here , the immunotherapeutic properties of a vaccine prepared by transfection of
mouse fibroblasts with DNA from a
breast carcinoma (
SB-5b ) that arose spontaneously in a
C3H / He mouse ( H-2Kb ) were tested in
mice with intracerebral
breast cancer . -
pubmed
The results of two independent in vitro
cytotoxicity assays indicate that systemic cellular antitumor immunity was generated in
mice injected i.c . -
pubmed
MATERIAL AND METHODS : Fifteen
SCL patients suffering from
NDO and
incontinence were included in the study . -
pubmed
CONCLUSION :
BTA proved to be a highly effective treatment modality for
NDO and
incontinence in
SCL patients . -
pubmed
Caspofungin , an antifungal agent that is a member of the
echinocandin family , an inhibitor of glucan synthesis in the fungal wall , is active against
Aspergillus and
Candidae infections . -
pubmed
CASE SUMMARY : This report describes a case of invasive
Aspergillus sinusitis in a kidney transplant recipient with
diabetes mellitus . -
pubmed
The
AmBisome had to be discontinued due to
deterioration of renal and hepatic function , but the
patient completed a further 7 - week course of
caspofungin alone . -
pubmed
CONCLUSION : This case indicates that
caspofungin is effective to treat invasive
Aspergillus sinusitis in kidney transplant recipients . -
pubmed
BACKGROUND : Noroviruses are common pathogens in
gastro - enteritis outbreaks in
humans worldwide . -
pubmed
CONCLUSIONS : In Hungary , emerging recombinant noroviruses became the second most common norovirus variants - next to
GGII-4 / Lordsdale virus - causing epidemics of
gastroenteritis in the last 4 years . -
pubmed
Successful rapid discontinuation of immunosuppressive therapy at molecular
relapse after allogeneic bone marrow transplantation in a pediatric
patient with
myelodysplastic syndrome . -
pubmed
The success of allogeneic bone marrow transplantation ( allo - BMT ) in
children with
myelodysplastic syndrome (
MDS ) is mainly affected by
relapse . -
pubmed
The role of additional immunotherapy for pediatric
patients with
MDS relapsing after allo - BMT remains to be established . -
pubmed
Because immunotherapy is generally more effective for
patients who bear a low
tumor burden , monitoring of
minimal residual diseases ( MRD ) is essential for early diagnosis at molecular
relapse . -
pubmed
NICU
patients are at particularly high risk of harm and even
death from medical error . -
pubmed
METHODS : A
human squamous cell carcinoma line (
KB ) , two
human osteosarcoma cell lines from mandible (
HOSM-1 ,
HOSM-2 ) , and the
human gingiva - derived fibroblast line (
HF ) , representing normal cells , were used . -
pubmed
The macro and microscopical characteristics of
hepatic lesions , together with the finding of
F. - pubmed
Currently ,
infliximab is the drug of choice for the treatment of
patients with active
AS associated with
IBD . -
pubmed
Early voluntary exercise does not promote healing in a
rat model of
Achilles tendon injury . -
pubmed
We observed the persistent presence of neutrophils in injured tendons of
rats that began exercise immediately after the
trauma [ injured + early exercise ( Inj+EEx ) ] . -
pubmed
Aging individuals with
HIV may be at risk for developing more age - related
cognitive decline , mild
cognitive impairment , or even
dementia . -
pubmed
OBJECTIVE : To compare growth , lipids and adipocytokines in
HIV - positive
children with and without
lipoatrophy . -
pubmed
PATIENTS : Eleven
HIV - positive
children with
facial lipoatrophy , and 22 age- and sex - matched
HIV - positive controls without signs of
fat abnormality . -
pubmed
Strikingly , despite similar
BMI z - scores and virological control ,
lipoatrophic patients were shorter by 1 standard deviation score ( p = 0.03 ) . -
pubmed
CONCLUSIONS : The presence of
facial lipoatrophy in a
child with
HIV infection is a marker for significant metabolic derangements including
dyslipidemia and
hypoadiponectinemia , and suggests the need for careful growth evaluation . -
pubmed
Rabies was diagnosed in a 40 kg
pig from a closed feeder barn in which recently unexplained
deaths of eight to ten
pigs had occurred . -
pubmed
Managing risk when considering the use of atypical antipsychotics for elderly
patients with
dementia - related
psychosis . -
pubmed
In 2005 , responding to several studies , the FDA issued a black box warning on atypical ( second generation ) antipsychotic medications , noting that the drugs may increase the risk of cerebrovascular adverse events in elderly
patients with
dementia - related
behavior disturbances . -
pubmed
Oxcarbazepine is an antiepileptic drug that has been approved by the US FDA and is indicated for use as monotherapy or adjunctive therapy in the treatment of partial
seizures in
adults and
children aged over 4 years . -
pubmed
In light of controlled and open - label prospective studies , it may be useful for
manic symptoms in the treatment of
bipolar and
schizoaffective patients . -
pubmed
In addition , owing to its lower propensity for drug interactions and side effects , it may be useful in the treatment of refractory
patients with
bipolar and schizoaffective disorder . -
pubmed
Subjective satisfaction of the
patients was evaluated on the basis of a questionnaire , in which hand function ,
pain and cosmetic appearance were recorded . -
pubmed
Long - lasting
pain relief was reported by 79 % and satisfaction with hand function by 90 % of the
patients . -
pubmed
Improvements in the range of motion and joint alignment and alleviation of
pain result in a markedly improved hand function and
patients ' satisfaction . -
pubmed
A
woman with
psoriasis vulgaris and
psoriatic arthritis developed
granulomatous rosacea after four weeks of therapy with
etanercept . -
pubmed
METHODS : Twenty - four primary
FSGS patients were transplanted at our centre from 1997 to 2007 . -
pubmed
The 15
ATIP patients using hematopoietic stem cell transplantation ( HSCT ) under minimum nonmyeloablative conditioning was performed using living donors . -
pubmed
RESULTS : Mean serum
creatinine ( SCr ) values of the 12
ATIP patients who were doing well at 1 , 3 , 5 years and at present were : 1.62 , 1.48 , 1.6 , and 1.92 mg% , respectively , on
cyclosporine ( 1.5 + /- 1 mg / kg per day ) and
prednisone ( 7.5 mg / day ) . -
pubmed
Four
patients displayed
recurrences at 8 days , 1 month , and 1 and 2 years posttransplant . -
pubmed
One
patient died at 1 year posttransplant ; one
patient received a subsequent
cadaver donor graft and two are on maintenance dialysis . -
pubmed
[ Changes of blood pressure and
pulse rate and the microstructure of celiac
ganglion in
rabbits with damaged celiac
ganglion induced by high intensity focused ultrasound and
alcohol ] . -
pubmed
CURRENT GUIDELINES : At present , appropriate treatment for
girls with
TS may include growth - promoting therapy and pubertal induction with the dual aims of optimizing adult height and facilitating psychosocial adjustment . -
pubmed
Olanzapine compared to
quetiapine in
adolescents with a first
psychotic episode . -
pubmed
OBJECTIVE : To compare the efficacy , safety , and tolerability of
olanzapine and
quetiapine in
adolescents with
first episode psychosis . -
pubmed
METHOD : Fifty
adolescents ( age 16 + /- 1.25 ) with a first episode of
psychosis were randomized to
quetiapine or
olanzapine in a 6 - month open label study . -
pubmed
We have investigated the in vitro antitumor activity of the mushroom
Agaricus blazei Murill on
human cancer cell lines as well as its potential anticancer activity in a model of
rat colon
carcinogenesis . -
pubmed
The in vitro anticancer analysis was performed using 9
human cancer cell lines incubated with organic and aqueous extracts of
A. - pubmed
Investigation of
ethanol - induced
impairment of spatial memory in gamma2 heterozygous knockout
mice . -
pubmed
PURPOSE : To investigate hemodynamic response to volume replacement with saline solution and hypertonic hydroxyethyl starch in
hypovolemic dogs . -
pubmed
Recurrent
malignant peripheral nerve sheath tumour in a
patient with
neurofibromatosis Type 1 : a case report . -
pubmed
We report a 58 - year - old
patient with known
neurofibromatosis Type 1 (
NF-1 ) who presented with an aggressive recurrent
malignant peripheral nerve sheath tumour and
spinal cord compression 5 weeks after undergoing
tumour excision with thoracic ( T)6 - 7 laminectomy . -
pubmed
The case and literature review are instructive to those following
NF-1 patients with regards to screening for , and management of , malignant conversion of
plexiform neurofibroma . -
pubmed
STUDY OBJECTIVE : Past studies have shown that acute experimental reduction of time in bed in otherwise healthy , non - sleepy
people leads to
hyperalgesia . -
pubmed
We hypothesized that otherwise healthy , sleepy
people may also exhibit
hyperalgesia relative to their non - sleepy counterparts . -
pubmed
CONCLUSION : This suggests that sleepy
individuals experience
hyperalgesia in response to a painful stimulus when compared with non - sleepy
individuals . -
pubmed
OBJECTIVES : The purpose of this study was ( i ) to document the average depths and density of adnexal structures in non - lasered facial and non - facial body skin ; ( ii ) to determine
injury in ex vivo
human thigh skin with varying fractional laser modes ; and ( iii ) to evaluate the clinical safety and efficacy of treatments . -
pubmed
Histological studies of samples from
human thigh skin demonstrated that increased fluencies in the superficial , deep and combined mode resulted in predictable deeper levels of ablations and
thermal injury . -
pubmed
Here we report that
nicotine ( 1 microM ) suppresses in vitro hyperexcitability of colonic dorsal root ganglia ( DRG ) ( L(1)-L(2 ) ) neurons in the dextran
sodium sulfate ( DSS)-induced
mouse model of acute colonic
inflammation . -
pubmed
Nicotine gradually reduced regenerative multiple - spike action potentials in
colitis mice to a single action potential . -
pubmed
This clinical case reports a 31 - year - old
man with
bilateral long finger metacarpal head avascular necrosis , treated with osteochondral mosaicplasty . -
pubmed
Studies have consistently demonstrated that early EN is safe and well tolerated , showing a reduction in
wound morbidity and healing , fewer
septic complications , diminished
weight loss , and improved protein kinetics in
patients administered early EN . -
pubmed
Both of them significantly extended the replicative lifespan of the K6001
yeast strain . -
pubmed
BACKGROUND : This study compared the results of
patients treated for
ulnar impaction syndrome using an ulnar shortening osteotomy ( USO ) alone with those treated with combined arthroscopic debridement and USO . -
pubmed
CONCLUSIONS : Both USO alone and combined arthroscopic TFCC debridement with USO improved the wrist function and reduced the level of
pain in the
patients treated for
ulnar impaction syndrome . -
pubmed
Acute inflammation triggered by enteric pathogens , such as
Salmonella enterica serotype Typhimurium (
S. - pubmed
Herein , we analyzed ciliary ultrastructural defects in 22
children with
MPP and determined the association of these defects with prognosis . -
pubmed
The recovery time in
patients with
multiple abnormalities was longer than that in patients with single abnormality . -
pubmed
A preliminary sketch of
horn cancer transcriptome in
Indian zebu cattle . -
pubmed
Horn cancer , a type of
squamous cell carcinoma , in zebu
cattle is an expensive affair in Indian agriculture sector , which accounts for 83.34 % of total
tumors found . -
pubmed
We employed Roche 454 next generation sequencing platform to sequence
Bos indicus cancerous and
normal horn tissue transcripts . -
pubmed
This study for the first time provides primary transcriptome sketch of
Bos indicus horn cancer tissue , and also demonstrates the suitability of the 454 sequencer for transcriptome analysis , which supports the concept of varied gene expression in cancerous condition . -
pubmed
In addition , we compared
estrogen and
testosterone levels in Japanese postmenopausal
women with and without
fractures . -
pubmed
Estrogen concentrations in postmenopausal
women were associated with
BMD ; however , no association was found between sex hormone levels and the presence of
fractures . -
pubmed
Patients either transmitted electrocardiograms ( ECGs ) daily or upon experiencing
cardiac symptoms . -
pubmed
Of the 70
patients included , 25 were diagnosed with
PAF . -
pubmed
Patients with
stroke had more episodes of
AF ( 56.5 + -106.3 versus 6.7 + -85.9 , p=0.685 ) and symptomatic
AF episodes ( 9.8 + -17.5 versus 4.9 + -8.1 , p=0.381 ) than the patients who did not have a
stroke , but the differences were not statistically significant because of the low numbers of patients and episodes . -
pubmed
Clinical trials established
aspirin plus
clopidogrel as the standard dual anti - platelet therapy in
patients with
ACS and
patients undergoing percutaneous coronary intervention ( PCI ) with stenting . -
pubmed
Prasugrel is the next approved
thienopyridine that has shown superior efficacy in
ACS patients undergoing PCI in comparison to
clopidogrel , although at the cost of a higher
bleeding risk . -
pubmed
The data so far suggests that
ticagrelor has a wider applicability in usage in
patients with
ACS as compared to
prasugrel . -
pubmed
Results of the present study demonstrate that
IRL-1620 , administered on day 1 , provides significant neuroprotection till 7 days after the induction of
cerebral ischemia in
rats . -
pubmed
Risk of
thiazide - induced
hyponatremia in
patients with
hypertension . -
pubmed
Facial appearance reflects
human familial longevity and
cardiovascular disease risk in healthy individuals . -
pubmed
In DKO
mice , diffuse lymphocytic infiltration was seen in submandibular glands , a major target of
pSS , by age 6 wk , progressing to severe
inflammation by age 12 wk . -
pubmed
Curcumin is a
polyphenol derived from the rhizome of
Curcuma longa whose pharmacological effects include antioxidant , anti - inflammatory and anti -
cancer properties . -
pubmed
Cisplatin neurotoxicity is clinically evident in
patients that have undergone a full course of chemotherapy and develop a
peripheral neuropathy that may affect the treatment regimen and the
patient 's qualify of life . -
pubmed
All but two of these
patients developed
BMs after becoming castration - resistant . -
pubmed
Effects of
pitavastatin and
atorvastatin on lipoprotein oxidation biomarkers in
patients with
dyslipidemia . -
pubmed
METHODS AND RESULTS : The VISION ( Value of oxIdant lipid lowering effect by Statin InterventiON in
hypercholesterolemia ) Trial randomized
patients with
hypercholesterolemia to 12 - week administration of
pitavastatin 2 mg / day ( n = 21 ) or
atorvastatin 10 mg / day ( n = 21 ) and a variety of lipoprotein oxidative biomarkers were measured . -
pubmed
CONCLUSIONS : The VISION study describes the first comparison on lipoprotein oxidation biomarkers between
pitavastatin and
atorvastatin and suggests diverse effects on lipoprotein oxidation markers in
patients with
hypercholesterolemia . -
pubmed
CT scan showed
pneumothorax in 92
patients . -
pubmed
Osteomalacia and
insufficiency fracture in a hemodialysis
patient with
autosomal dominant polycystic kidney disease . -
pubmed
A 61 - year - old Japanese
woman on hemodialysis with
autosomal dominant polycystic kidney disease (
ADPKD ) was admitted to the hospital with
gluteal pain . -
pubmed
This case emphasizes that
vitamin D deficiency and
malnutrition can cause
osteomalacia in dialysis
patients , even if
calcium (
Ca ) and
phosphate ( P ) levels are controlled by calcium carbonate . -
pubmed
A 30 - year - old
man with
fever ,
myalgias ,
arthritis , and
rash . -
pubmed
We reviewed 111
patients diagnosed with
early - stage ovarian cancer who had undergone primary surgery at Hacettepe Hospital between 1984 and 2001 , using diagnostic criteria from the WHO-2003 classification . -
pubmed
FIGO - stage and mitotic count were significant for survivals of 59
patients with
cancer . -
pubmed
The
patients with stage - II
cancer had 5.65 times more risk of
recurrence than stage - I
cancer . -
pubmed
National estimates of GW burden in
sexually transmitted disease (
STD ) clinic settings are useful to provide a baseline assessment to monitor and evaluate reductions in GW and serve as an important early measure of
human papillomavirus (
HPV ) vaccine impact in this population . -
pubmed
Given the opportunity for prevention with a quadrivalent
HPV vaccine , STD clinics may be an ideal setting for monitoring trends in
GW prevalence among men ( MSW and MSM ) . -
pubmed
SUBJECTS AND METHODS : We reviewed medical records retrospectively for 325
patients diagnosed with
IE between January 1 , 1987 , and March 31 , 2012 . -
pubmed
Among
patients with
head and neck squamous cell carcinoma with a negative neck who are initially treated with ( chemo)radiotherapy , a number of cases will recur locally without obvious neck
recurrence . -
pubmed
The risk of occult neck node
metastasis in a clinically rN0
patient correlated with
tumor site and T stage . -
pubmed
For
patients with more advanced laryngeal
recurrences or
recurrence at other high - risk sites , neck dissection could be considered for the rN0 patient , particularly if the neck was not included in the previous radiation fields . -
pubmed
Tumorigenesis in vivo was assessed using a
mouse xenograft model . -
pubmed
Antimicrobial Susceptibility Pattern of
Burkholderia cepacia Isolates from Patients with
Malignancy . -
pubmed
In this report , we describe a case of
mesenteric venous thrombosis in a young
woman caused by a vaginal contraceptive ring . -
pubmed
It seems logical to assume a similar beneficial effect in
children hospitalised for an acute
asthma exacerbation . -
pubmed
MAIN RESULTS : Seven randomised trials were included , four of which reported usable data on 472
children with
asthma one to 18 years of age who were admitted to paediatric wards . -
pubmed
These findings support current national and international recommendations indicating that healthcare practitioners should refrain from using anticholinergics in
children hospitalised for acute
asthma . -
pubmed
METHODS : This study involved 33
patients ( 20 high - grade and 13 low - grade
gliomas ) . -
pubmed
OBJECTIVE : To assess the relationship between
AD - related pathological changes in
human brain tissue , ventricular and lumbar CSF , and brain interstitial fluid ( ISF ) . -
pubmed
METHODS : Altogether 11
patients with suspected
idiopathic normal pressure hydrocephalus underwent frontal cortical brain biopsy , 24 - h intraventricular pressure monitoring , and a microdialysis procedure . -
pubmed
We therefore intended to study the relationship between the ventilatory response to
CO2 and the
impairment of lung function in
DM1 patients . -
pubmed
Sixty - nine
DM1 patients were prospectively investigated ( 43.5 + - 12.7 years ) . -
pubmed
Thirty - one
DM1 patients ( 45 % ) presented a ventilatory restriction , 38 ( 55 % ) were
hypoxaemic and 15 ( 22 % ) were
hypercapnic . -
pubmed
Ventilatory response to
CO2 was neither different among restricted / non - restricted
patients ( p = 0.2395 ) nor among normoxaemic /
hypoxaemic subjects ( p = 0.6380 ) . -
pubmed
The reduced ventilatory response to
CO2 in
DM1 patients appeared independent of lung function impairment and
respiratory muscle weakness , suggesting a central cause of
CO2 insensitivity . -
pubmed
Ginseng Purified Dry Extract , BST204 , Improved
Cancer Chemotherapy - Related
Fatigue and Toxicity in
Mice . -
pubmed
A large proportion of
cancer patients experience
cancer - related physical and central
fatigue so new strategies are needed for treatment and improved survival of these
patients . -
pubmed
PURPOSE : To investigate the causes of late - onset , progressive
neurological deficits in
patients with severe
angular kyphosis caused by
spondylitis secondary to
tuberculosis (
TB spondylitis ) . -
pubmed
METHODS : From 2000 to 2011 , 36
patients with severe
angular kyphosis secondary to
TB spondylitis (
TB kyphosis ) were enrolled in the study . -
pubmed
All
patients had late - onset , progressive
neurological deficits . -
pubmed
Group A ( n = 25 , 69.4 % ) comprised
patients whose
neurological deficits resulted from the
kyphosis itself . -
pubmed
Patients in group B ( n = 11 , 30.6 % ) had developed neurological symptoms related to a lesion cephalad or caudal from the
kyphosis . -
pubmed
CONCLUSIONS : In their evaluation of paraplegic
patients , spine surgeons should consider the many potential causes of late - onset
neurological deficits in
TB spondylitis to avoid performing unnecessary surgery . -
pubmed
Lugol chromoendoscopic screening for
esophageal dysplasia / early
squamous cell carcinoma in
patients with esophageal symptoms in low - risk region in China . -
pubmed
In the chromoendoscopy group , 213
patients had unstained lesions of & gt;0.5 cm , the detection rates of
dysplasia / early
carcinoma were 5.3 % ( 4/76 ) in those with lesions of 0.5 - 1.0 cm , and 37.2 % ( 51/137 ) in those with lesions & gt;1.0 cm ( chi2=21.46 , P<0.001 ) . -
pubmed
Forty - two
critically ill patients requiring PiCCO - Plus cardiac output monitoring were prospectively studied . -
pubmed
Thirty older
adults ( 69.0 + - 4.2 years of age ) were studied on two separate occasions on both the WBB and a stationary isometric dynamometer (
SID ) . -
pubmed
Trauma date ,
patient gender and age , mechanism and anatomic topography of
injury , surgical management , need for surgical re - intervention , hospitalization period ,
postoperative complications , mortality and limb amputation rates were analyzed . -
pubmed
RESULTS : One hundred seventy - three
patients with 255
vascular injuries were analyzed ; 95.95 % were male ( p<0.05 ) , mean age of 28.92 years ; 47.4 % were caused by firearm projectiles ( p<0.05 ) ; topographic distribution : 45.66 % lower limbs ( p<0.05 ) , 37.57 % upper limbs , 6.94 % abdominal , 5.2 % thoracic and 4.62 % were
cervical vascular injuries ; 51.42 % of patients required hospitalization for seven days or less ( p<0.05 ) ; limb amputation was necessary in 15.6 % and the overall mortality was 6.36 % . -
pubmed
We report herein on an ex vivo
conjunctival inflammation and
squamous metaplasia model by culturing
human conjunctival tissues at an air - liquid interface for up to 8 days to study the effects of
minocycline on
inflammation and
squamous metaplasia . -
pubmed
CONTEXT :
3,5 - Diiodo - L - thyronine (
3,5 - T2 ) is a thyroid hormone metabolite which exhibited versatile effects in
rodent models , including the prevention of
insulin resistance or
hepatic steatosis typically forced by a high - fat diet . -
pubmed
Salivary oxidant/ antioxidant status and hematological parameters in
patients with
recurrent aphthous stomatitis . -
pubmed
METHODS : This case - control study consisted of 28
patients with
RAS and 28 age and sex -matched control without
RAS . -
pubmed
Detection of
CHLAMYDIA PSITTACI in feral
pigeons (
COLUMBA LIVIA DOMESTICA ) in Slovakia and their characterisation . -
pubmed
INTRODUCTION AND OBJECTIVES :
Chlamydia psittaci , an obligate intracellular bacterium , which is the etiologic agent of
avian chlamydiosis in birds and
ornithosis /
psittacosis in
humans , has been reported to be one of the most common pathogens found in feral pigeons worldwide , and thus constitutes a zoonotic risk . -
pubmed
We have treated a series of 15
patients with 17
fractures of the condylar head , in which the use of ultrasound - activated resorbable fixation has provided adequate strength and stability during early healing . -
pubmed
MATERIALS AND METHODS : Sixty - one
patients ( 43
men and 18
women ; mean [ + - SD ] age , 65.8 + - 8.6 years ; age range , 44 - 82 years ) with 71
HCCs ( mean [ + - SD ] size , 2.8 + - 0.9 cm ; range , 0.7 - 4.2 cm ) underwent combined TACE and RFA . -
pubmed
Aggressive intrasegmental
recurrence was observed in one
patient ( representing 1.4 % of all treated
HCCs and 4.5 % of periportal
HCCs ) after treatment of a 4.0 - cm periportal
HCC . -
pubmed
HIV /
AIDS knowledge , attitudes and behaviour of persons with and without disabilities from the Uganda Demographic and Health Survey 2011 : Differential access to HIV /
AIDS information and services . -
pubmed
Recommendations are also made for the inclusion of disability measures in Uganda 's
AIDS Indicator Survey to provide cyclical and systematic data on disability and HIV /
AIDS , including
HIV prevalence amongst persons with disabilities . -
pubmed
Multiple stressors including contaminant exposure and
parasite infection predict spleen mass and energy expenditure in breeding
ring - billed gulls . -
pubmed
The objective of this study was to determine how multiple physiological stressors (
parasite infection and contaminant exposure ) and natural challenges ( energy - demanding activities and weather conditions ) may affect DEE in nesting
ring - billed gulls (
Larus delawarensis ) exposed to high concentrations of persistent organic contaminants ( POPs ) . -
pubmed
Fighting
tuberculosis by drugs targeting nonreplicating
Mycobacterium tuberculosis bacilli . -
pubmed
Drugs were less effective in
C3HeB / FeJ mice forming caseous
granulomas . -
pubmed
Clinical implications of blood eosinophil count in
patients with
non - asthma - COPD overlap syndrome COPD . -
pubmed
We investigated the clinical implications of the blood eosinophil count in
patients with
non - ACOS COPD . -
pubmed
Cancer of the Breast in a
Man . -
pubmed
Hepatic performance of the
patients ,
thrombotic events ,
inflammatory disorders and
autoimmune system activation must be the main concerns together with necessary precautions . -
pubmed
Methods : Our retrospective monocentric study was based on 130
patients followed on a regular basis , with
acromegaly controlled by medical treatments or cured by surgery or radiation technique . -
pubmed
Conclusions : The follow - up of
glucose disorders needs to be maintained on a long - term basis in
patients controlled for
acromegaly . -
pubmed
Materials and Methods : Sixty - one
patients with
cervical cancer were included in this study from June 30 , 2015 to April 30 , 2017 . -
pubmed
RESULTS : There were 534
patients with
aortic stenosis , 254 with
aortic regurgitation , 61 with
aortic stenoregurgitation , 19 with
infective endocarditis , and 5 with a previous aortic valve procedure . -
pubmed
Fifteen
patients needed reoperation ( 13 infective
endocarditis , 1 break of thread , and 1 tear of cusp case ) . -
pubmed
CONCLUSIONS : The midterm outcomes of AVNeo using autologous pericardium were satisfactory in 850
patients with various
aortic valve diseases . -
pubmed
Biological trials of peritoneally injected Abu - TGIRIS - Abu - NH2 gave an evidence of its better efficacy versus
immunocortin in a test for suppression of the experimental
autoimmune encephalomyelitis (
EAE ) in Dark Agouti ( DA )
rats . -
pubmed
Comparison of non - invasive assessment of
liver fibrosis in
patients with
alpha1 - antitrypsin deficiency using magnetic resonance elastography ( MRE ) , acoustic radiation force impulse ( ARFI ) Quantification , and 2D - shear wave elastography ( 2D - SWE ) . -
pubmed
PURPOSE : Although it has been known for decades that
patients with
alpha1 - antitrypsin deficiency (
AATD ) have an increased risk of
cirrhosis and
hepatocellular carcinoma , limited data exist on non - invasive imaging - based methods for assessing
liver fibrosis such as magnetic resonance elastography ( MRE ) and acoustic radiation force impulse ( ARFI ) quantification , and no data exist on 2D - shear wave elastography ( 2D - SWE ) . -
pubmed
METHODS : Fifteen clinically asymptomatic
AATD patients ( 11 homozygous PiZZ , 4 heterozygous PiMZ ) and 16 matched healthy volunteers were examined using MRE and ARFI quantification . -
pubmed
This study was aimed to examine the potential treatment effect of intravenous lipid emulsion on
rat liver tissue in the
toxicity of
malathion . -
pubmed
RESULTS : The prevalence of
AF in
HCM patients has gradually increased to 1.6 - fold from 13.4 % in 2005 to 20.9 % in 2015 . -
pubmed
The prevalence of
stroke in
HCM patients was approximately 10 % , while that in
HCM patients with
AF was about 20 % . -
pubmed
We report the first case of a gasless robot - assisted nipple - sparing mastectomy and immediate reconstruction in a
patient with early
breast cancer . -
pubmed
Fisetin suppresses migration , invasion and stem - cell - like phenotype of
human non - small cell lung carcinoma cells via attenuation of epithelial to mesenchymal transition . -
pubmed
Cautious approach in intraoperative inspired
oxygen fraction is required for
patients susceptible to
postoperative pulmonary complications . -
pubmed
Cell
death is a common driver of
human disease and is frequently studied in a variety of in vitro settings . -
pubmed
All
patients fulfilling the in-/exclusion criteria and presenting full data sets on lesion diameter , lesion color , as well as
pain perception for baseline ( day 0 ) and 4 and 7 days after treatment were enrolled into the presented study . -
pubmed
Both groups showed equal distribution in
patient 's age , sex and presented a similar mean lesion size ( 3.0 + - 1.0 mm ) , lesion color distribution as well as
pain perception at baseline . -
pubmed
All
patients showed significant normalization of lesion color , reduction of
pain , and lesion dimension within the course of their treatment . -
pubmed
METHODS : A 16 - week RCT training intervention was conducted in
overweight premenopausal
women randomized into three groups : a team handball training group without prior experience ( UN ; n = 13 ) , a team handball group with prior experience ( EXP ; n = 10 ) , and an inactive control group ( CON ; n = 9 ) . -
pubmed
Moreover , the synthesized nanoparticles ( NPs ) demonstrate potent
cytotoxicity against
human U87 glioblastoma cells by inducing cell apoptosis via triggering intracellular ROS overproduction . -
pubmed
The full - length genome of four Moroccan
vvIBDV strains was determined , in order to get a more exhaustive molecular characterization allowing to conduct the evolution time scale and speculations on their origin . -
pubmed
In a phylogenetic tree , nucleotide sequences of segment A and B formed a common branch with those
vvIBDV references
strains published in GenBank , but they clearly grouped into a distinct subcluster . -
pubmed
The purpose of this study was to evaluate the effect of
BMI percentile on sagittal alignment in
AIS patients compared with nonscoliotic adolescents . -
pubmed
METHODS : Posterior - anterior and lateral spinal radiographs of 1,551
AIS patients with a thoracic major curve ( Lenke 1 - 4 ) and 70 nonscoliotic adolescent
patients were compared . -
pubmed
RESULTS : Coronal plane
deformity magnitude was not significantly different between the 4 categories of
AIS patients ( p = .51 ) . -
pubmed
This was also true in obese
adolescents without
spinal deformity ( p < .04 ) . -
pubmed
Lumbar lordosis , pelvic incidence , and pelvic tilt were not significantly different between
AIS patients in the four
BMI percentile categories ( p > .07 ) . -
pubmed
Pelvic incidence was significantly greater in
AIS patients compared with nonscoliotic adolescents ( 54 + - 13 vs. 46 + - 11 ; p = .01 ) . -
pubmed
CONCLUSION : Increased
BMI percentile is associated with increased
thoracic kyphosis in
AIS patients and nonscoliotic adolescents . -
pubmed
AIS patients have an increased pelvic incidence compared with nonscoliotic adolescents ; however , this variable is not influenced by body mass . -
pubmed
A 45 - year - old Japanese
man presenting with
leg purpura ,
abdominal pain , and
arthralgia was diagnosed with
IgA vasculitis . -
pubmed
The
blood loss was approximately 10800ml and the
patient received transfusions of 48 units of concentrated red blood cells , 18 units of fresh frozen plasma , and 30 units of concentrated platelets . -
pubmed
Rarely , massive
bleeding ,
perforation ,
intussusception , and/or
intestinal obstruction occur in the gastrointestinal tract and these complications affect
patients ' prognoses . -
pubmed
The clinical course in the present patient indicated that severe
bleeding from the gastrointestinal tract can occur even after symptom remission in
patients with
IgA vasculitis . -
pubmed
Comparing
wound complications associated with midline and flank approaches for spaying
cats . -
pubmed
Using a non - randomized clinical study design we assessed adult
rituximab naive
patients with
B - cell lymphoid malignancies from January 2017 to July 2019 . -
pubmed
The envelope following response ( EFR ) has been proposed as a non - invasive marker of
synaptopathy in
animal models . -
pubmed
The combined analysis of simulations and experimental data proposes that the DBEFRs extracted from the [ 2 - 6]-kHz frequency band is a sensitive and frequency - specific measure of
synaptopathy in
humans . -
pubmed
Rebuttal to letter " Is thromboprophylaxis with high - dose
enoxaparin really necessary for
COVID-19 patients ? -
pubmed
Members of
Fusarium graminearum species complex (
FGSC ) are the major pathogens that cause
Fusarium head blight (
FHB ) in cereals worldwide . -
pubmed
asiaticum with the
NIV chemotype was less aggressive than that with the
3ADON chemotype in
wheat , while the
NIV - producing
strains were more virulent than the
3ADON - producing
strains in
rice . -
pubmed
Chronic kidney disease (
CKD )
patients with
secondary hyperparathyroidism (
SHPT ) have an increased risk of
cardiovascular disease (
CVD ) . -
pubmed
Cinacalcet was administered to six
SHPT patients for a period of 8 weeks . -
pubmed
Furthermore , this aerogel exhibits the shortest clotting time and lowest
blood loss in
rat hemorrhage model . -
pubmed
Radiotherapy improves local and regional control in
patients with
breast cancer , and it could even improve relapse - free survival and overall survival in
patients with
nodal disease . -
pubmed
The
toxicity of this treatment in most cases is mild and transient , but in a low percentage of
patients , radiotherapy - induced
tumors may develop . -
pubmed
CASE PRESENTATION : Seven Colombian
patients treated for
breast cancer at our institution developed radiotherapy - induced
tumors between 2008 and 2018 . -
pubmed
Six
patients had locally advanced
tumors at the time
breast cancer was diagnosed , and all of them received neoadjuvant or adjuvant chemotherapy and radiotherapy . -
pubmed
Septic arthritis post anterior cruciate ligament reconstruction due to
Clostridioides difficile . -
pubmed
Clostridioides difficile is an obligate anaerobe ubiquitous in the environment and is of particular interest in the healthcare setting as a cause of healthcare associated
infection usually presenting with
colitis . -
pubmed
Blends of Gelucire 44/14 and
coconut oil were employed as lipid excipients to obtain suppository formulations with self - emulsifying properties , which were then tested in a TNBS (
2,4,6 - trinitrobenzenesulfonic acid ) induced
rat colitis model . -
pubmed
Effect of Secondary Prevention Medication on the Prognosis in
Patients With
Myocardial Infarction With Nonobstructive
Coronary Artery Disease . -
pubmed
The role of secondary prevention therapy in
patients with
MINOCA remains unclear . -
pubmed
This study aimed to evaluate the associations between secondary prevention medications and outcomes in
patients with
MINOCA . -
pubmed
A total of 259
patients with
MINOCA were consecutively enrolled . -
pubmed
About 19.1 % of
patients with
MINOCA suffered adverse events during the follow - up period . -
pubmed
Objective : Catheter ablation combined with left atrial appendage closure ( LAAC ) has emerged as a promising strategy for
atrial fibrillation (
AF )
patients at high risk for
stroke or with contraindications for oral anticoagulants ( OACs ) . -
pubmed
Methods : From October 2015 to December 2017 , a total of 76 consecutive non - valvular , drug - refractory
AF patients who underwent a combined procedure of CBA and LAAC are included . -
pubmed
With a mean follow - up time of 23.7 + - 11.0 months , the
recurrence of
atrial arrhythmia was recorded in 35
patients ( 48.0 % ) . -
pubmed
Among the 72
patients ( 94.7 % ) who underwent TEE , one patient ( 1.4 % ) had device - related
thrombosis and one patient ( 1.4 % ) had prominent residual flow ( over 3 mm ) . -
pubmed
This study examined the effect of acupuncture stimulation in the vicinity of the cervical - sympathetic
ganglion on respiratory function in
humans . -
pubmed
In
Sr2 + - Tyrode lacking
Ca2 + all three toxins exhibited the same immediate
depression followed by facilitation in the
rat and
mouse diaphragms , but the final blocking activity was only 3 - 10 % with beta - bungarotoxin and crotoxin and was 30 % with taipoxin . -
pubmed
The authors report the results of a randomized study in which comparison was made between two different kinds of treatment in
patients affected by uncomplicated
duodenal ulcer endoscopically diagnosed . -
pubmed
Chronic unremitting , generally symmetric , erosive
polyarthritis was studied in 8
dogs . -
pubmed
The disease had clinical , serologic , radiographic , and pathologic changes similar to those of
rheumatoid arthritis of
man . -
pubmed
The condition occurred mainly in smaller breeds of
dogs , with time of onset from 8 months to 8 years of age , Characteristic radiographic changes were seen in the joints several weeks to several months after the appearance of the initial
lameness . -
pubmed
The effect of various doses of specific serum administered in passive immunization on the formation of primary and secondary adaptive immunity in
mice of the CBA
strain was studied . -
pubmed
Scalp infections occurred in children and were due either to
Microsporum canis or
Microsporum ferrigineum . -
pubmed
Over the past 20 years the Orthopaedic Oncology Unit of the Massachusetts General Hospital has performed over 660 massive cadaveric allograft transplantations , mostly for
patients with
bone tumors . -
pubmed
To determine whether the
oats - related extra
spots were derived from mycotoxin contamination , two groups of
rats were fed either Wayne diet or Wayne diet containing
zearalenone ( 0.05 mg / kg ) for three weeks . -
pubmed
It probably results from reactivation of
infection by
Epstein - Barr virus (
EBV ) and usually presents as bilateral white patches on the lateral borders of the tongue . -
pubmed
Diagnosis of
hairy leukoplakia should normally be confirmed by demonstrating
EBV in the koilocyte - like cells by immunocytochemistry or DNA in situ hybridization . -
pubmed
[ Possibility of ovulation induction using
naloxone in
women with
hypothalamic amenorrhea ] . -
pubmed
Within the study we treated 6
women suffering from
hypothalamic amenorrhea with 4 mg
naloxone intravenous daily . -
pubmed
The other
women ( non - responder in
Naloxone - Test ) reaches a follicular growth till 17 mm follicle diameter following in
preterm atresia during therapy . -
pubmed
This decrease was markedly delayed in the liver of
hypothyroid rats . -
pubmed
This increase was markedly delayed in the liver of
hypothyroid rats . -
pubmed
Mice were then observed for survival or sacrificed at day 21 after
tumor inoculation to determine size of primary
tumor , numbers and size of lung
metastases , and other hematological parameters including numbers of granulocyte - macrophage progenitor cells ( CFU - gm ) . -
pubmed
Human papillomaviruses are oncogenic viruses that have been found in a variety of
epithelial neoplasias . -
pubmed
Human papillomavirus type-16 DNA was found in four of the five
tumors , including two
tumors that contained both type-16 and type-18 DNA . -
pubmed
[ Clinical observations on the treatment of
hookworm , Ascaris and
Trichuris infection with
oxibendazole ] . -
pubmed
The purpose of this study was to determine what advantages the use of paramagnetic contrast material might have in evaluating
patients clinically suspected of having
spinal infection . -
pubmed
Our results showed the following advantages of
gadolinium - enhanced MR : it ( a ) provided excellent anatomical delineation of all
epidural abscesses , routinely differentiating them from the adjacent compressed thecal sac even when this was not possible by noncontrast MR ; ( b ) increased observer confidence in the diagnosis of
disk space infection and
osteomyelitis in
patients with equivocal noncontrast MR ; ( c ) localized those portions of paraspinal masses most likely to yield a positive percutaneous biopsy ; and ( d ) identified active
infections from those that had responded adequately to antibiotic therapy . -
pubmed
We studied transepithelial potential difference ( PD ) in normal
persons ,
patients with
chronic disease , and
patients with
cystic fibrosis (
CF ) , using the technique described by Knowles and co - workers . -
pubmed
These data confirm the observation that
patients with
CF have hyperpolarized nasal epithelia that demonstrate greater change in response to
amiloride than that in non - CF controls . -
pubmed
In a randomized clinical trial the effects of selective digestive decolonization ( SDD ) on the frequency of
pneumonia and
sepsis and the rate of lethality as well as the resistance quota and colonization of bacteria were studied in 102 surgical ICU -
patients requiring prolonged mechanical ventilation . -
pubmed
Immunologic patterns in
CAPD patients with
peritonitis . -
pubmed
In a third of the
patients these
cysts are associated with
malformations of CNS a./o . -
pubmed
Nude rats and thymus - grafted
nude rats were susceptible to
infection with
T. - pubmed
mentagrophytes but only thymus - grafted
nude rats cleared the
dermatophytosis . -
pubmed
Clearance of the
fungal infection took twice as long ( approximately 60 days ) in thymus - grafted nude
rats when compared with heterozygous euthymic ( + /RNU ) controls ( approximately 35 days ) . -
pubmed
Following clearance of the primary
dermatophytosis , peritoneal exudate cells ( PEC ) were adoptively transferred from either thymus - grafted or heterozygous
rats to
nude rats . -
pubmed
All heterozygous ( + /RNU )
rats , thymus - grafted nude
rats ( 4/4 ) , and 8 of 12 PEC - recipient
nude rats , which had cleared a primary
dermatophytosis also expressed delayed - type
hypersensitivity and elevated serum antibody titers to trichophytin antigen . -
pubmed
mentagrophytes in the
rat is T cell - dependent , and that the absence of functional T lymphocytes and not an epithelial defect results in chronic
dermatophytosis in the
nude rat . -
pubmed
A cellular analysis of 330
middle ear effusions ( MEEs ) from
children with
otitis media with effusion (
OME ) was performed with the use of cytocentrifuge prepared smears and the results were compared with their clinical data . -
pubmed
Information was sought on the phenotype of lymphoid cells causing lethal
graft - vs - host disease (
GVHD ) in irradiated
mice expressing whole or partial H-2 differences . -
pubmed
Children and adolescents with
IBD are at risk for serious
thromboembolic complications . -
pubmed
The Casella reaction and the
permanganate - induced
basophilia of
human elastica . -
pubmed
[ Corneal sensitivity in
patients following surgery for
retinal detachment ] . -
pubmed
Subcutaneous growth and transplantation of the
RS 1 rat tumor into adult unconditioned
golden hamsters . -
pubmed
Histaminemia in
guinea pigs inoculated with
Junin virus ] . -
pubmed
The size of the second and third mandibular molar teeth of inbred
mice is altered if the
mice are fostered on a different
strain . -
pubmed
None of these
persons had any signs of
pancreatic disease . -
pubmed
Sugar cataracts in
Mongolian gerbil (
Meriones unguiculatus ) . -
pubmed
Mongolian gerbils (
Meriones unguiculatus ) given a 50 %
galactose diet developed
cataracts similar to those produced in
rats maintained on the same diet . -
pubmed
The first sign of a
cataract appeared 24 hr after feeding
gerbils on the high
galactose diet . -
pubmed
The pace of
cataract maturation was observed to be about twice of that in
rats , although the blood
galactose levels were similar in the two
species . -
pubmed
The
gerbil thus appears to be another suitable model for the study of
sugar cataracts . -
pubmed
[ Initial experience with an operation for
pulmonary artery narrowing in young
children with patent common atrioventricular canal ] . -
pubmed
METHODS AND RESULTS :
Hamster hearts were obtained for RNA isolation and analysis and in situ hybridization from two groups : normal control
animals ( n = 4 ) and untreated
cardiomyopathic hamsters ( n = 5 ) . -
pubmed
The case of a 77 - year - old
woman with a 6/5/4.5 cm , mobile , hard , white - yellowish
tumour associated with
axillary adenopathy , with a progressive evolution in the upper external frame of the right breast is presented . -
pubmed
It is proposed that the phenomena of
psychosis ( including negative symptoms ) can be understood as part of the diversity of
human personality structure generated by a process of sexual selection acting on a sexual dimorphism for cerebral asymmetry . -
pubmed
The
dogs were followed for
endocrine and exocrine pancreatic insufficiency . -
pubmed
Two
dogs ( 13 % ) developed radiation - induced morbidity which consisted of a common
bile duct stenosis and an enterocolic
fistula , as was confirmed at autopsy after 8 and 18 months , respectively . -
pubmed
After a follow - up of 1 year , none of the
dogs had developed
pancreatitis ,
diabetes or
exocrine insufficiency . -
pubmed
The first , that
yeast respiratory activity protects anaerobic rumen bacteria from damage by
O2 , was tested using different
strains of
yeast that had previously been shown to have differing abilities to increase the viable count of rumen bacteria . -
pubmed
Forty - three
patients with T3
glottic carcinomas and treated by a combination of total laryngectomy and radiotherapy were studied . -
pubmed
The difference in peristomal
recurrence between the tracheostomy and non - tracheostomy
patients was not statistically significant . -
pubmed
In this case a
patient ( aged 57 years ) suffering from a recurrent
larynx papillomatosis was treated with PDT . -
pubmed
After treatment the
patient was admitted to an intensive care unit for 24 h. 3 h after photoradiation , general urticarial wheals arose , as well as
tachycardia and a decrease in blood pressure followed by all the signs of serious
anaphylaxis . -
pubmed
Moreover , QA produced a marked
hyperactivity , an inability to use the forelimbs to retrieve food pellets in a staircase test , increased the latency of the
rats to remove adhesive stimuli from their paws , and decreased the number of steps taken in a bracing test that assessed
motor rigidity . -
pubmed
A 60 - year - old
man underwent transfrontal surgery for a
macroadenoma of the pituitary which presented with
chiasmal compression , and immunohistochemical examination of the resected specimen revealed a
corticotrophic tumour . -
pubmed
PATIENTS AND METHODS : A review of 127
patients with
non - metastatic osteosarcoma of the extremity , treated between March 1983 and June 1986 , was performed . -
pubmed
None of the
patients who relapsed with local or distant
recurrences other than lung
metastasis are now alive . -
pubmed
All of the
patients who were not surgically treated had
disease progression and died within 40 months after the first
recurrence . -
pubmed
RESULTS : In all 35 cases of
adults melanoma malignum was diagnosed and confirmed anatomopathologically . -
pubmed
In 7 among 20
children the appearance of
tumor was not confirmed by anatomopathologic findings . -
pubmed
CONCLUSIONS : Special attention should be paid to the improvement of
intraocular tumor diagnosis , particularly in
children . -
pubmed
DATA SYNTHESIS : Low - risk
patients with single - vessel
coronary artery disease and normal left ventricular function had greater alleviation of symptoms with PTCA than with medical treatment ; mortality rates and rates of
myocardial infarction were unchanged . -
pubmed
In high - risk
patients ( risk was defined by severity of
ischemia , number of diseased vessels , and presence of
left ventricular dysfunction ) , improvement of survival was greater with CABG than with medical therapy . -
pubmed
In moderate - risk
patients with multivessel
coronary artery disease ( most had two - vessel disease and normal left ventricular function ) , PTCA and CABG produced equivalent mortality rates and rates of
myocardial infarction . -
pubmed
In moderate - risk
patients , PTCA and CABG produce similar mortality rates and rates of
myocardial infarction but PTCA - treated
patients require more revascularization procedures . -
pubmed
We studied the electrophysiological parameters of motor performance in eight
patients with
multiple sclerosis and troublesome
fatigue , before and after treatment with
3,4 - diaminopyridine . -
pubmed
After a 3 - week course of
3,4 - diaminopyridine ( 25 - 60 mg / day ) , six out of the eight
patients reported substantial improvement in
fatigue and the group showed slightly less
fatigue on the exercise test . -
pubmed
A group of 20
patients underwent plastic surgery for
inguinal hernia . -
pubmed
This reflex is potentiated by
shock exposure and associative
shock conditioning ( in
animals and
human volunteers ) and unpleasant pictures ( in
human volunteers ) . -
pubmed
Investigation of oxidant stress and vasodepression to
glyceryl trinitrate in the
obese Zucker
rat in vivo . -
pubmed
We examined the relationship between oxidant stress and the vasodepressor activity of
glyceryl trinitrate (
GTN ) in vivo , including rapid
GTN tolerance development , in 13 - week old
obese and age - matched lean Zucker
rats which had been maintained for 4 weeks on either control diet or diets enriched with the lipophilic , chain - breaking antioxidants
vitamin E ( 0.5 % w w(-1 ) ) or
probucol ( 0.5 % w w(-1 ) ) or the
superoxide anion scavenger
tiron ( 1 % w v(-1 ) in drinking water ) . -
pubmed
The basal plasma level of the
isoprostane 8 - epi - PGF2alpha , an in vivo marker of lipid peroxidation , was elevated by approximately 5 fold in the
obese Zucker rat and markedly reduced by dietary lipophilic antioxidants and depressed by dietary
tiron . -
pubmed
, was impaired in
obese animals and completely restored by dietary antioxidants . -
pubmed
appeared more severe in
obese animals . -
pubmed
However , rapid
nitrate tolerance was not affected by dietary antioxidants in either the
obese or lean Zucker
rat . -
pubmed
We therefore provide evidence that elevated oxidant stress in the
obese Zucker
rat is associated with an impairment in
nitrate vasodepressor activity . -
pubmed
OBJECTIVE : To evaluate the incidence and mechanism of
beta - lactam adverse reactions during an 8 - year period in all episodes of suspected
infective endocarditis in
patients treated at a university - affiliated institution . -
pubmed
A total of 121 low - velocity
gunshot fractures were evaluated in 107
patients . -
pubmed
Visual function deficits in
children . -
pubmed
In the past year , new work on sensory testing in preverbal infants has expanded our knowledge in three areas : 1 ) visual acuity testing in
infants in varying levels of illumination ; 2 ) visual evoked cortical potential - evidence for binocular function in
infantile esotropia ; and 3 ) a new time - efficient method to evaluate color vision in newborns and infants . -
pubmed
We describe the case of a 7 - year - old
girl who was clinically diagnosed as having a
pontine glioma based on magnetic resonance imaging studies . -
pubmed
Aerosol - derived airway morphometry and aerosol bolus dispersion in
patients with
lung fibrosis and
lung emphysema . -
pubmed
OBJECTIVE :
Patients with
lung emphysema show increased aerosol - derived dimensions of peripheral airspaces and increased aerosol bolus dispersion ( AD ) . -
pubmed
DESIGN : This study was designed as a cross - sectional study in which airspace dimensions and
AD in
patients with
emphysema and in
patients with
fibrosis were compared . -
pubmed
Forty
patients participated in the study : 20
patients had high - resolution CT ( HRCT)-proved
lung emphysema and 20
patients had HRCT - proved
lung fibrosis . -
pubmed
RESULTS :
Patients with
lung emphysema showed normal dimensions of small airways but enlarged airspace dimensions in the lung periphery . -
pubmed
AD was increased in
patients with
emphysema but was normal in patients with
fibrosis . -
pubmed
Patients with signs of general
arteriosclerosis or those in whom upper abdominal resection has been performed previously may benefit from angiography . -
pubmed
METHODS : Fifteen
rats were randomized into three equally large groups and sustained to either thoracic laminectomy or to severe
spinal cord compression trauma of the Th 8 - 9 segments . -
pubmed
The non -
trauma group contained laminectomized
animals submitted to a hypothermic procedure in which the core temperature was reduced from 38 to 30 degrees C. The two
trauma groups were either submitted to the same hypothermic procedure or kept normothermic during the corresponding time . -
pubmed
CONCLUSIONS : This study demonstrates reduced axonal swelling in the peri -
injury zones of
spinal cord injured rats treated with systemic
hypothermia . -
pubmed
Patients with previous paroxysmal
atrial fibrillation had lower left atrial appendage ejection fractions than
patients in
sinus rhythm without paroxysmal
atrial fibrillation ( 33 + /- 14 vs. 47 + /- 14 % , p & lt ; 0.001 ) . -
pubmed
More than half of the
patients ( 7/13 [ 54 % ] ) with previous paroxysmal
atrial fibrillation showed delayed and incomplete opacification of the left atrial appendage with Albunex . -
pubmed
CONCLUSION : We conclude that paroxysmal
atrial fibrillation causes
left atrial appendage stunning , at least in some
patients . -
pubmed
OBJECTIVE : The aim of this systematic review was to evaluate all controlled trials of autogenic training ( AT ) as a means of reducing stress and
anxiety levels in
human subjects . -
pubmed
This clinical report documents
rectal toxicity from a large cohort of
men treated by a single practitioner for
adenocarcinoma of the prostate . -
pubmed
Four
patients ( 0.5 % ) reported Grade 3 rectal
toxicity with rectal
ulceration identified on colonoscopy at 1 year from implant . -
pubmed
In 3 of the 4
patients the Grade 3 rectal
toxicity has resolved spontaneously and 1
patient continues to heal at the time of this report . -
pubmed
The authors report the case of a
patient undergoing anterior pelvic exenteration for
cancer of the urethra with sigmoid colon urinary diversion and vaginal reconstruction using a colonic segment . -
pubmed
METHODS : Twelve
patients with advanced
malignant tumors involving the shoulder girdle or the proximal humerus underwent forequarter amputation ( FQA ) for palliative purposes . -
pubmed
Lung
metastases were the dominant cause of
death in our
patients . -
pubmed
CONCLUSIONS : The results of FQA in our series point to its feasibility and the gain in quality of life and performance status in severely ill
patients with advanced
malignancies . -
pubmed
Amblyomma testudinarium tick
bite : one case of engorged adult and a case of extraordinary number of
larval tick infestation . -
pubmed
This paper reports two recent cases of
tick bite due to
Amblyomma testudinarium . -
pubmed
To our knowledge , the latter case is the eleventh case of larval
tick bites among all tick species and the fourth case with larval
A. - pubmed
The term "
strawberry gallbladder " refers to an anatomo - pathological aspect which is included in the wider chapter of
gallbladder cholesterolosis . -
pubmed
Splenic lymphoproliferative disorders in
human T lymphotropic virus type - I endemic area of japan : clinicopathological , immunohistochemical and genetic analysis of 27 cases . -
pubmed
Here we characterized
splenic lymphomas in an
human T lymphotropic virus type - I ( HTLV - I ) endemic area of Japan . -
pubmed
Cases were divided into primary
splenic lymphoma in 11
patients and secondary in 16
patients . -
pubmed
Follow - up of 26
patients indicated that all but one
patient with primary
lymphoma were still alive ( range , 1 - 89 months ) and 8 of 15
patients with
secondary lymphomas died due to the progression of
malignant lymphoma ; the survival rate at 2 years was 50 % in these
patients . -
pubmed
In situ hybridization for
Epstein - Barr virus (
EBV ) showed no reactivity of
lymphoma cells , although a few small lymphocytes were positive for
EBV . -
pubmed
Hepatitis C virus was observed in 6 of 20 ( 30 % )
patients examined and 4 of 11 ( 36 % ) cases of primary
splenic lymphoma . -
pubmed
METHODS : 188 unselected
patients , seen at an interdisciplinary dermatorheumatologic outpatient clinic , were clinically examined for the presence of
ANT and possible associations to preexisting disease . -
pubmed
The mean age of
ANT patients was 57.5 + /- 8.2 years . -
pubmed
CONCLUSIONS :
ANT is not uncommon among
patients attending a dermatorheumatologic outpatient clinic . -
pubmed
We have performed a retrospective study including a non consecutive series of 92
patients presenting both
BPH and
inguinal hernia . -
pubmed
Selected parameters of
blood coagulation and fibrinolysis were evaluated in 20
patients with
squamous cell carcinoma of the oral cavity ( stages T2/4 N0/3 M0 ) . -
pubmed
We conclude that , in
patients treated surgically because of
carcinoma of the oral cavity , there might be increased activity of the fibrinolytic system both prior to and after operation . -
pubmed
Semantic clustering in verbal fluency :
schizophrenic patients versus control participants . -
pubmed
BACKGROUND :
Schizophrenic patients generate fewer words than healthy controls during verbal fluency tasks . -
pubmed
METHODS : Twenty - four healthy controls and 24
patients with
schizophrenia participated in six , 3 min semantic fluency tasks . -
pubmed
The present study investigated the in vitro radiosensitizing effect of
flavopiridol and the underlying molecular mechanisms in a
murine ovarian cancer cell line ,
OCA - I. -
pubmed
All
patients responded well to therapy without
locomotive disability , and persistent
pain was uncommon . -
pubmed
CONCLUSION :
Septic sacroiliitis should be considered in peripartum
patients who present with
fever and severe
localized pain . -
pubmed
Diamond blackfan anemia stem cells fail to repopulate erythropoiesis in
NOD / SCID mice . -
pubmed
When tested in vivo ,
folate - targeted liposomes were found to deliver approximately 1.8 - fold more
oligonucleotide to the livers of
nude mice ( relative to the nontargeted
PEG - containing formulations ) ; however , no improvement in KB
tumor uptake was observed . -
pubmed
Detection and characterization of
measles virus strains in cases of
subacute sclerosing panencephalitis in Croatia . -
pubmed
Studies on
acute disseminated encephalomyelitis produced experimentally in
rhesus monkeys . -
pubmed
We conclude that the development of
cytomegaly is inhibited by
Fe chelation and may be facilitated by an
HCMV - induced increase in the LIP . -
pubmed
OBJECTIVE : To investigate clinical effect , liver pathohistological changes ( including pathology ,
HBV markers in liver tissue ) in
patients with
chronic hepatitis B. -
pubmed
METHODS : 70
patients of
chronic hepatitis B were administered 100 mg
Lamivudine orally daily for 1 year . -
pubmed
First experience with
gemtuzumab ozogamicin plus
cytarabine as continuous infusion for elderly
acute myeloid leukaemia patients . -
pubmed
We treated with GO in combination with
cytarabine as continuous perfusion nine elderly
AML patients , either untreated ( five cases ) , or with relapsed / refractory disease ( four cases ) . -
pubmed
Larger prospective studies are now warranted in order to better define the possible role of this regimen in the treatment of elderly
AML patients . -
pubmed
Experimentally induced
ulcers and gastric sensory - motor function in
rats . -
pubmed
In earlier studies using positron emission tomography ( PET ) with the tracer
alpha [( 11 ) C ] methyl - l - tryptophan (
AMT ) , we reported global and focal abnormalities of
serotonin synthesis in
children with
autism . -
pubmed
In the present study , we measured brain
serotonin synthesis in a large group of
autistic children ( n = 117 ) with
AMT PET and related these neuroimaging data to handedness and language function . -
pubmed
K - complex values of
autistic children with asymmetry or no asymmetry in cortical
AMT uptake followed different developmental patterns , compared to that of a control group of non - autistic
children . -
pubmed
Five - year follow - up of
patients with epidemic
glomerulonephritis due to
Streptococcus zooepidemicus . -
pubmed
BACKGROUND : In 1998 there was a large outbreak of acute
glomerulonephritis in Nova Serrana , Brazil , caused by group C
Streptococcus zooepidemicus . -
pubmed
Patients with reduced
creatinine clearance were older than those without
reduced renal function ( 54+/-15 vs 34+/-12 years , P<0.001 ) . -
pubmed
CONCLUSIONS : After a mean time of 5.4 years , a relatively high proportion of
patients with epidemic
poststreptococcal glomerulonephritis due to
S.zooepidemicus present
hypertension ,
reduced renal function and increased
microalbuminuria . -
pubmed
Determination of these SNPs in ( future ) transplant recipients has the potential to identify
individuals who are at risk of under - immunosuppression or the development of
adverse drug reactions . -
pubmed
Formalin fixed paraffin embedded
tumour samples of 10
patients and adjacent
non - malignant controls were analysed by radioactive labelled riboprobe in situ hybridisation ( isH ) and immunohistochemistry . -
pubmed
The results also imply the existence of a cumulative exposure time or dose threshold for
alcohol if promoting effects of cessation are to be seen on
rat hepatocarcinogenesis . -
pubmed
Women completed tests of memory , learning , and executive functioning , and hot
flush and sleep assessments at baseline and study end . -
pubmed
Facial paralysis may occur as a complication of
central nervous system leukemias in
children , but it is rarely a presenting symptom . -
pubmed
This report describes an 8 - month - old
child who presented with
peripheral facial palsy ,
failure to thrive ,
anemia , and
otitis media . -
pubmed
This case should alert physicians to consider
hematologic malignancies in
children with
facial paralysis . -
pubmed
Here , we report on the results of 3 years of
pamidronate treatment in 10
children and
adolescents with
OI type VI ( age range 0.8 to 14.5 years , three
girls ) . -
pubmed
Our results suggest that 3 years of intravenous
pamidronate therapy led to improvements in bone mineral mass , gross motor function , muscle force and
fracture incidence in
patients with
OI type VI . -
pubmed
1034
children ( 91.8 % ) were dentally examined to assess their normative needs for 6 types of treatment ( dental
caries ,
traumatic dental injuries ,
enamel defects , periodontal , orthodontic and prosthodontic treatment ) . -
pubmed
Orf is a
parapoxvirus infection of
sheep and
goats that causes
blistering lesions on the lips , nostrils , udders or toes of affected animals . -
pubmed
The 80 % aqueous
acetone extracts from the fruit ( 50 mg / kg / d ) and seeds ( 12.5 and 25 mg / kg / d ) of
Rosa canina L. , but not from the pericarps , were found to show substantial inhibitory effect on the gain of
body weight and/or weight of visceral fat without affecting food intake in
mice for 2 weeks after administration of the extracts . -
pubmed
With regard to the active constituents , the principal constituent ,
trans - tiliroside ( 0.1 - 10 mg / kg / d ) , potently inhibited the gain of
body weight , especially visceral fat weight , and significantly reduced blood
glucose levels after
glucose loading ( 1 g / kg , ip ) in
mice . -
pubmed
We describe the case of a
patient with
neurofibromatosis type 1 (
NF1 ) complicated by severe
pulmonary aterial hypertension (
PAH ) ; only seven cases have been reported on this association so far , and
PAH seems to be related to the vascular involvement of
neurofibromatosis . -
pubmed
On the basis of histological findings and of the results of genetic study we believe that
PAH was a complication of
NF1 in our patient and we suggest to screen
patients with
NF1 for the presence of PAH by means of trans - thoracic echocardiogram . -
pubmed
Evaluation of tongue pressure on the inferior dental arch in
patients with
mandibular prognathism . -
pubmed
UNLABELLED : The aim of the present study was to find out whether there is a difference between the force exerted by the tongue ( pressure ) in
patients with
mandibular prognathism and healthy controls and to determine the difference in tongue pressure on the inferior dental arch in
patients with
mandibular prognathism before and after mandibular setback . -
pubmed
MATERIAL AND METHODS :
Patients with
mandibular prognathism were compared with healthy controls and data on tongue pressure were collected . -
pubmed
RESULTS : Tongue pressure on the inferior dental arch in
patients with
mandibular prognathism ranged from 1.98 N to 12.26 N ( mean 5.356 N ) . -
pubmed
Tongue pressure in the control group ranged from 2.36 N to 16.9 N ( mean 6.56 N ) , with most of the values ranging from 4.02 N to 7.84 N. CONCLUSIONS : Tongue pressure on the inferior dental arch is reduced in
patients with
mandibular prognathism . -
pubmed
METHODS : Subjects were 230 healthy
volunteers , 18 to 30 years of age with no history of
alcohol or
drug dependence . -
pubmed
The epidermis , the outer layer of the skin composed of keratinocytes , is a stratified epithelium that functions as a barrier to protect the
organism from
dehydration and external insults . -
pubmed
This paper reports a case of
coccidioidal pericarditis diagnosed by an in - house
Coccidioides posadasii antigen and confirmed with mycological and molecular methods . -
pubmed
Direct thrombin inhibitors are commonly used anticoagulants in
patients with known or suspected
heparin - induced
thrombocytopenia (
HIT ) . -
pubmed
We describe a 26 - year - old pregnant
woman with
portal vein thrombosis and
thrombocytopenia treated with
argatroban for possible
HIT during her last trimester . -
pubmed
Even though the cause of this
patient 's
thrombocytopenia was later determined to be
idiopathic thrombocytopenic purpura , this is an important case that adds to the literature on use of
argatroban during pregnancy . -
pubmed
[
Yakon tea induced
hepatitis in a patient with
alcoholic liver cirrhosis ] . -
pubmed
To test this hypothesis , we analyzed
sterol esters in plasma and tissues in
patients having non -
cholesterol sterols (
sitosterolemia and
Smith - Lemli - Opitz syndrome ) . -
pubmed
Relationship between postoperative infectious complications and glycemic control for
diabetic patients in an orthopedic hospital in Kuwait . -
pubmed
OBJECTIVE : To study the relationship between postoperative infectious complications and glycemic control for
diabetic patients in an orthopedic hospital in Kuwait . -
pubmed
RESULTS : Of 318
diabetic patients who underwent surgical operations , 90 ( 28.3 % ) developed
postoperative complications ; HbA(1c ) & lt;7 % was significantly associated with decreased infectious complications with an adjusted odds ratio of 2.51 ( 95 % confidence interval , 1.20 - 2.89 ) . -
pubmed
Regarding types of complications , urinary tract infectious complications were significantly higher among those
patients with HbA(1c ) & gt ; or = 7 % ( p & lt ; 0.0001 ) , while other complications (
SSI ,
lower respiratory tract infection and
sepsis ) showed nonsignificant differences ( p & gt ; 0.05 ) . -
pubmed
Prophylaxis by antibiotics with preoperative
patient preparation , proficient surgical technique and postoperative
wound care is recommended for uncontrolled
diabetics subjected to surgery . -
pubmed
METHOD : Three
patients with
PLA were identified from the ward registion files and were retrospectively reviewed . -
pubmed
Two
patients were diagnosed with
hepatocellular carcinoma and one with
metastatic cholangiocarcinoma . -
pubmed
Two
patients were subjected to biopsies showing features of inflammatory
pseudotumor before a diagnosis of
hepatocellular carcinoma . -
pubmed
CONCLUSIONS : This series of cases highlights the importance of considering underlying
hepatobiliary malignancies in
patients with
PLA and a close follow - up necessary for non - resolving
hepatic lesions . -
pubmed
Characteristic mutations in
hepatitis C virus core gene related to the occurrence of
hepatocellular carcinoma . -
pubmed
Previous studies have shown that there might be some characteristic mutations in the core region of
HCV related to
HCC . -
pubmed
Whole genome survey of copy number variation in the spontaneously
hypertensive rat : relationship to quantitative trait loci , gene expression , and blood pressure . -
pubmed
The aim of our study was to determine whether copy number variants ( CNVs ) exist between the spontaneously
hypertensive rat ( SHR ) and its control
strain , the Wistar - Kyoto
rat , whether these map to quantitative trait loci in the
rat and whether CNVs associate with gene expression or blood pressure differences between the 2
strains . -
pubmed
Acute ST - elevation
myocardial infarction in young
patients : 15 years of experience in a single center . -
pubmed
BACKGROUND : There have been few studies done regarding young
patients with
ST - elevation myocardial infarction (
STEMI ) . -
pubmed
The purpose of this study was to investigate the clinical characteristics and coronary angiographic features in young
patients with
STEMI . -
pubmed
METHODS : We collected data on 849 consecutive
patients with
STEMI from 1992 to 2006 . -
pubmed
RESULTS : Young
patients presented 11.6 % of all
patients with
STEMI . -
pubmed
Because of an unpredicted and unavoidable shortage in global supplies of
imiglucerase for
Gaucher disease , we collected clinical and laboratory data from
patients who were evaluated & lt;= 6months before drug withdrawal and then retested before / during reinstatement of therapy . -
pubmed
Although we no longer think that drug vacations should be considered as a form of maintenance for
patients requiring enzyme therapy for
Gaucher disease , but if necessary - for compelling personal reasons - one may be reassured that a short - term drug interruption is not likely to lead to irreversible complications or return to baseline values of critical clinical parameters . -
pubmed
The
Charles Bonnet syndrome (
CBS ) is a condition associated with complex
visual hallucinations occurring in the elderly in
patients with
visual impairment and normal mental health . -
pubmed
Here , we report the case of a 78 - year - old
woman who has a limited visual acuity with a
CBS that we postulated to be in relationship to a
vitamin B12 deficiency . -
pubmed
Radiological techniques are important in evaluating
patients with
gastrointestinal bleeding . -
pubmed
Scintigraphic , computed tomographic angiographic , and enterographic techniques are sensitive tools in identifying the source of
bleeding and may be useful in identifying patients likely to have a benign course and in selecting
patients for therapeutic intervention . -
pubmed
With the refining developments in body imaging and related reconstructive techniques , it is likely that radiological interventions will play an expanding and critical role in evaluating
patients with
gastrointestinal hemorrhage in the future . -
pubmed
Splenectomy following
abdominal trauma is rare in
children . -
pubmed
We report two cases of
children requiring splenectomy following severe blunt
abdominal injury . -
pubmed
We wish to highlight these radiological features of
splenic avulsion as they can help to focus management decisions regarding the need / timing for a laparotomy following blunt
abdominal trauma in
children . -
pubmed
We present a case of
paraffinoma in a 64 - year - old
woman , which occurred in the eyelid after endoscopic
sinus surgery for chronic
sinusitis . -
pubmed
Rib metastases from a
non - tonsillar squamous cell carcinoma in a
dog . -
pubmed
The
dog presented with a history of a rapidly growing
SCC of the right upper incisive region , which was confirmed by histopathology as a
SCC . -
pubmed
Although
erectile dysfunction (
ED ) is a frequent complaint in
patients with
DM1 , it has not been investigated in great depth . -
pubmed
Patients with hormonal evidence of
interstitial failure had a larger CTG expansion ( p = 0.008 ) , longer disease duration ( p = 0.013 ) , higher grade of disease ( p = 0.004 ) and lower erectile function score ( p = 0.02 ) than eugonadic
patients . -
pubmed
Impotence occurred in 13/14 hypogonadic
patients with
interstitial failure and in 5/12 eugonadic
patients ( p = 0.017 , OR = 18.2 ) . -
pubmed
Recent studies present data on
patient - reported outcomes and show that the benefit of suppression of
joint damage progression is maintained over time . -
pubmed
Many of these analogues had MIC & lt;= 0.25 mug / mL against
quinolone - resistant
MRSA strains . -
pubmed
The MICs of these select ITQs versus a panel of clinical
MRSA strains were determined , and the ITQs were found to have 8- to 16 - fold greater potency than
linezolid . -
pubmed
We compared
patient outcomes following neoadjuvant or adjuvant systemic chemotherapy for cT2 - T4aN0 - N2M0
bladder cancer . -
pubmed
METHODS : In a retrospective review of a single institutional database from 1988 through 2009 , we identified
patients receiving neoadjuvant or adjuvant multiagent
platinum - based systemic chemotherapy for locally advanced
bladder cancer . -
pubmed
With regard to the limited efficacy of currently available anti -
dementia drugs it is crucial to investigate whether such treatments also provide clinically meaningful benefits to cognitively impaired older
individuals . -
pubmed
METHODS : We conducted a systematic review of randomized controlled trials evaluating cognition - focused interventions in
participants with
mild cognitive impairment or
dementia . -
pubmed
We describe a
patient with multiple metachronous
bone metastases from lower
rectal cancer who was successfully treated with multimodal treatment including surgical resections and has shown 32 mo disease - free survival . -
pubmed
Surgical resection of metastatic bone lesion(s ) from
colorectal cancer may be a good treatment option in selected
patients . -
pubmed
Use of acupuncture therapy as a supplement to conventional medical treatments for acute
ischaemic stroke patients in an academic medical centre in Korea . -
pubmed
This study was conducted to estimate the usage rate of acupuncture as a supplemental treatment in
acute ischaemic stroke patients and to identify factors associated with the choice to use this therapy . -
pubmed
METHODS : Using the registry of
stroke patients admitted to an academic medical centre in Korea , the use of acupuncture therapy was recorded and analysed , along with the
patients ' socio - demographic characteristics , hospital access variables , risk factors for
ischaemic stroke and clinical characteristics . -
pubmed
After controlling for other significant factors , there was an approximately 3.4 - fold greater usage in
patients with moderately severe
strokes ( 95 % confidence interval ( CI)=2.5 - 4.6 ) and 4.1 - fold greater usage in
patients with severe
strokes ( 95 % CI=2.7 - 6.4 ) . -
pubmed
CONCLUSIONS : The findings provide a better understanding of
patients ' utilization of acupuncture therapy as a supplement to conventional medical treatments and of factors associated with the utilization of acupuncture in
patients with
acute ischemic stroke . -
pubmed
Participants were interviewed and tested for
HIV and
STIs . -
pubmed
METHODS : A total of 165
patients ( 104 with acute and 61 with
chronic urticaria ) from a tertiary referral hospital were enrolled in this study . -
pubmed
Morphological and immunohistochemical characterization of spontaneous
thyroid gland neoplasms in
guinea pigs (
Cavia porcellus ) . -
pubmed
Reports of
thyroid gland neoplasms in
guinea pigs (
Cavia porcellus ) are rare , but
thyroid tumors are among the most common
neoplasms seen in cases submitted to Northwest ZooPath . -
pubmed
This report describes the histological and immunohistochemical characteristics of
thyroid neoplasms and lists the concurrent conditions found in
guinea pig cases submitted to Northwest ZooPath during 1998 to 2008 . -
pubmed
Of 526
guinea pig case submissions , 19 had
thyroid neoplasms . -
pubmed
Neoplasms were removed as an excisional biopsy from 7
guinea pigs , and 3 of these animals died within a few days after surgery . -
pubmed
Research is needed to determine the appropriate modalities for antemortem diagnosis and treatment and whether
thyroid disease plays a role in the pathogenesis of
chronic degenerative diseases in
guinea pigs . -
pubmed
We currently use
Mucor circinelloides as a model organism to develop
strains able to produce new , more valuable , and with an increased content of carotenoids . -
pubmed
Bronchiolitis associated with exposure to artificial butter flavoring in
workers at a cookie factory in Brazil . -
pubmed
OBJECTIVE : To report the cases of four
patients with
bronchiolitis caused by exposure to artificial butter flavoring at a cookie factory in Brazil . -
pubmed
RESULTS : All four
patients were young male nonsmokers and developed persistent
airflow obstruction ( reduced FEV1 / FVC ratio and FEV1 at 25 - 44 % of predicted ) after 1 - 3 years of exposure to
diacetyl , without the use of personal protective equipment , at a cookie factory . -
pubmed
CONCLUSIONS :
Bronchiolitis resulting from exposure to artificial flavoring agents should be included in the differential diagnosis of
airflow obstruction in
workers in Brazil . -
pubmed
Identification and characterization of the functional toxboxes in the
Vibrio cholerae cholera toxin promoter . -
pubmed
METHODS : The study was conducted in
patients of
COPD in
TB chest department of a medical college hospital . -
pubmed
Human adipose - derived stromal / stem cells : a novel approach to inhibiting acute
pancreatitis . -
pubmed
Accumulated data suggest
human adipose - derived stromal / stem cells would be a valuable tool for cell - based therapy for
inflammatory disease ,
autoimmune disease , tissue repair , and ischemic insults by controlling cell
death , immune response ,
inflammation , and tissue regeneration . -
pubmed
Thus , it is reasonable to hypothesize that
human adipose - derived stromal / stem cells would be a novel approach to inhibiting
inflammation and reducing acute
pancreatitis . -
pubmed
Dahl ( S x R )
rat congenic
strain analysis confirms and defines a chromosome 17 spatial navigation quantitative trait locus to & lt;10 Mbp . -
pubmed
METHODS : A model was developed using NONMEM ( ) version 7.2 based on RBC data obtained from 48
patients with
RA receiving once - weekly low - dose
MTX treatment . -
pubmed
BACKGROUND : Since sedatives are often administered to immune - compromised and
critically ill patients , our understanding of immunomodulation by sedation will be critical . -
pubmed
CONCLUSIONS :
Dexmedetomidine can have beneficial effect on preoperative or
postoperative inflammatory bowel disease patients in intensive care units by down - regulating inflammatory immune response not only in systemic circulation but also in tissue - specific manner . -
pubmed
Timely anticoagulation introduction in asymptomatic
patients may impact on the
stroke rate . -
pubmed
According to the results of repeated Monte Carlo simulations based on a real population of 166
patients , daily monitoring may reduce the 2 - year
stroke risk by 9 - 18 % with an absolute reduction of 0.2 - 0.6 % , compared with conventional inter - visit intervals of 6 - 12 months . -
pubmed
Whereas imaging studies commonly show hippocampal activation during short - delay memory tasks , evidence from amnesic
patients with
MTL lesions is mixed . -
pubmed
MATERIAL AND METHOD : One hundred and twenty consecutive
patients with
steatosis or normal liver , assessed by ultrasound by the same expert , were enrolled . -
pubmed
[ Clinical features and treatment of acute
clenbuterol poisoning in
children ] . -
pubmed
OBJECTIVE : To study clinical features , treatment and curative effects in
children with acute
clenbuterol poisoning , in order to provide a basis for early diagnosis and treatment . -
pubmed
METHODS : Clinical data of 28 hospitalized
children with acute
clenbuterol poisoning in April 2011 were retrospectively studied . -
pubmed
Vomiting ,
palpitations and
limb shaking were found as main clinical manifestations in the
patients . -
pubmed
CONCLUSIONS : Acute
clenbuterol poisoning is characterized by
vomiting ,
palpitations ,
limb shaking ,
hypokalemia ,
lactic acidosis and
tachycardia in
children . -
pubmed
Phenotypic and genotypic coefficients of variation , heritability , and genetic advance were estimated for : time to vine emergence , leaf size , leaf
virus infection , plant leafiness , shoot height , vine dry weight , number of tubers per hill and tuber yield per hill in
white yam (
Dioscorea rotundata Poir . ) -
pubmed
Improving
cytopenia with splenic artery embolization in a
patient with
paroxysmal nocturnal hemoglobinuria on
eculizumab . -
pubmed
We describe a
patient under treatment with the anti - complement antibody
eculizumab who developed
pancytopenia , requiring blood transfusions , due to massive
splenomegaly . -
pubmed
BACKGROUND : Endoscopic collateral ventilation assessment ( ECVA ) can be used to select
patients suffering from
emphysema for application of valves to achieve a reduction of lung volume . -
pubmed
METHODS :
Patients with severe
chronic obstructive pulmonary disease (
COPD ) underwent examination for a possible reduction of lung volume . -
pubmed
RESULTS : Of a tested 310
emphysema patients , 17 met criteria allowing ECVA ; 10 of 17 proved eligible for valve application . -
pubmed
CONCLUSIONS : Only a small portion of
patients with progressive
emphysema of the lung seem suitable for endoscopic reduction of lung volume by application of valves . -
pubmed
Hypothesizing a continuum between
emesis gravidarum and
HG , we investigated
androgen concentrations in
women with
HG . -
pubmed
STUDY DESIGN : In a case - control study , 32
women hospitalized for
HG were compared with 29 control
women scheduled for elective surgical abortion . -
pubmed
CONCLUSION :
Steroid hormone homeostasis may be altered in
women with
HG . -
pubmed
Impact of acellular mucin pools on survival in
patients with complete pathological response to neoadjuvant treatment in
rectal cancer . -
pubmed
The objective of this study was to determine impact of acellular mucin pools on disease free and overall survival in
patients with complete pathological response to neoadjuvant chemoradiotherapy in rectal
cancer . -
pubmed
METHODS : One hundred and seventy two
patients received neoadjuvant chemoradiotherapy for rectal
cancer and underwent surgery . -
pubmed
BACKGROUND : Guidelines now recommend high - intensity statins in all
individuals with
atherosclerotic cardiovascular disease . -
pubmed
METHODS : SATURN ( Study of
Coronary Atheroma by Intravascular Ultrasound : Effect of
Rosuvastatin Versus
Atorvastatin ) employed serial intravascular ultrasound measures of
coronary atheroma volume in
patients treated with
rosuvastatin 40 mg or
atorvastatin 80 mg for 24 months . -
pubmed
CONCLUSIONS :
Women with
coronary disease demonstrate greater
coronary atheroma regression than men when empirically prescribed guideline - driven potent statin therapy . -
pubmed
Glioblastoma multiforme (
GBM ) is the prevalent and most fatal
brain tumor in
adults . -
pubmed
We evaluated the contribution of
headache chronicity to QOL in relation to clinical , psychiatric , and psychosocial variables in
patients with
migraine . -
pubmed
RESULTS : Among 251 eligible
patients , 183 ( 72.9 % ) had
episodic migraine (
EM ) and 68 ( 27.1 % ) had
chronic migraine (
CM ) . -
pubmed
Patients with
CM had more serious clinical ,
psychiatric , and poor QOL than did patients with
EM . -
pubmed
Triple immunosuppressive therapy in
steroid - resistant
nephrotic syndrome children with
tacrolimus resistance or
tacrolimus sensitivity but frequently relapsing . -
pubmed
METHODS : Eighteen consecutive
children with
steroid- and
tacrolimus (
TAC)-resistant ( n = 10 ) or
TAC - sensitive but frequent relapsing
nephrotic syndrome ( n = 8) were randomly recruited in the present study . -
pubmed
RESULTS : Compared with previous double - combination therapy of
prednisone (
Pre ) and
TAC , the short - term remission rate in all 18
patients was significantly improved after the triple - combination therapy , while the frequent
relapse rate in the following 12 months was also significantly decreased . -
pubmed
CONCLUSION : Triple - combination therapy with Pre +
TAC +
CTX /
MMF /
LEF is effective for short - term response and 1 year remission , without significant additional side - effects seen in
children with
steroid - resistant and
tacrolimus - resistant or
tacrolimus - sensitive but frequently relapsing
nephrotic syndrome . -
pubmed
Classical swine fever (
CSF ) caused by CSF virus (
CSFV ) is a highly contagious and devastating disease that affects the
pig industry worldwide . -
pubmed
All animals were challenged with
CSFV C -
strain at 4 weeks and then boosted with the same dose . -
pubmed
The
rabbits inoculated with
CSFV-1.1E2 and CSFV-1.1 + 2.1E2 received complete protection against
CSFV C -
strain . -
pubmed
These results demonstrate that CSFV-1.1E2 and CSFV-1.1 + 2.1E2 not only elicit humoral and cell - mediated immune responses but also confer complete protection against
CSFV C -
strain in
rabbits . -
pubmed
PRESENTATION OF CASE : A 37 - year - old
woman complained of painless and reducible
swelling in her left groin , and referred to our hospital for surgical management against left
inguinal hernia with the incarcerated ovary . -
pubmed
The accurate diagnosis of an
inguinal hydrocele in a
female is seldom made . -
pubmed
CONCLUSION : Laparoscopic diagnosis and TEP treatment offers a useful alternative in selected
patients with
hydrocele of the canal of Nuck . -
pubmed
In this respect , it is known that the
patients who underwent radical nephrectomy due to
renal tumor are under high risk of
chronic kidney disease (
CKD ) in the long term . -
pubmed
70
patients who underwent donor nephrectomy as renal donors and 130
patients who underwent radical nephrectomy due to
renal tumor were studied . -
pubmed
Peripheral nerve injury is a serious problem affecting significantly
patients ' life . -
pubmed
Autografts are the " gold standard " used to repair the
injury gap , however , only 50 % of
patients fully recover from the
trauma . -
pubmed
METHODS : A single - institution retrospective study was performed with 331
patients who underwent radical resection of
thymoma between 1991 and 2012 . -
pubmed
Relapse occurred in 23
patients with the pleura ( 14 ) and
tumor bed ( 6 ) as the most common sites of
recurrence . -
pubmed
According to the definitions of the International Thymic Malignancy Interest Group , 10 ( 43.5 % )
patients had local
relapse , 15 ( 65.2 % ) had regional
relapse , 10 ( 43.5 % ) had distant
relapse . -
pubmed
The
recurrence - free survival rates in
patients with
tumor size & gt;=8 cm were worse than those of
patients with
tumor size & lt;8 cm ( P=0.007 ) . -
pubmed
Mixed
Infections and
Rifampin Heteroresistance among
Mycobacterium tuberculosis Clinical Isolates . -
pubmed
Mixed
infections and heteroresistance of
Mycobacterium tuberculosis contribute to the difficulty of diagnosis , treatment , and control of
tuberculosis . -
pubmed
We aimed to assess 1 - year prognosis in
patients experiencing silent
AF in
AMI . -
pubmed
METHODS : All consecutive
patients with
AMI who were prospectively analysed by CEM during the first 48 h after admission and who survived at hospital discharge were included . -
pubmed
Silent
AF was defined as asymptomatic episodes lasting at least 30 s.
Patients were followed up at 1 year for cardiovascular ( CV ) outcomes . -
pubmed
RESULTS : Among the 737
patients analysed , 106 ( 14 % ) developed silent
AF and 32 ( 4 % ) symptomatic
AF . -
pubmed
Compared with the no -
AF group ,
patients with silent
AF were markedly older ( 79 vs 62 years , p<0.001 ) , more frequently
hypertensive ( 71 % vs 49 % , p<0.001 ) and less likely to be smokers ( 23 % vs 37 % , p<0.001 ) . -
pubmed
However , a history of
stroke or
AF was less frequent in silent
AF than in symptomatic -
AF patients ( 10 % vs 25 % and 10 % vs 38 % , respectively ) . -
pubmed
Systematic screening and specific management should be investigated in order to improve outcomes of
patients after
AMI . -
pubmed
METHODS : With Institutional Review Board approval , 4 septic and 6 nonseptic extremely low
birth weight patients were enrolled . -
pubmed
The aim of this study was to assess the impact of CT - assessed
sarcopenia on short- and long - term outcomes in
patients undergoing surgical resection of
gastrointestinal and hepatopancreatobiliary malignancies . -
pubmed
WML were present in 103 ( 52.6 % )
individuals . -
pubmed
According to this classification ,
HBV carriers showing
acute hepatitis exacerbation were divided into 3 subgroups ; asymptomatic or inactive
HBV carriers without drug exposure , asymptomatic or inactive
HBV carriers developing
HBV reactivation during and after immunosuppressive therapies and/or antineoplastic chemotherapies and those with previously resolved
HBV infection showing iatrogenic
HBV reactivation . -
pubmed
In an annual nationwide survey in 2013 , however , a patient with previously resolved
HBV infection was enrolled , in whom
LOHF developed as a result of
HBV reactivation despite in the absence of immunosuppressive therapies and/or antineoplastic chemotherapies . -
pubmed
Thus , the study group revised the classification criteria in 2015 ;
HBV carriers developing acute
hepatitis exacerbation were classified into asymptomatic or inactive
HBV carriers and patients with previously resolved
HBV infection , and both groups were further sub - classified into those receiving immunosuppressive therapies and/or antineoplastic chemotherapies and those without such drugs exposure . -
pubmed
Evaluation of the potential for
QTc prolongation in
patients with
solid tumors receiving
nivolumab . -
pubmed
Role of
gefitinib in the targeted treatment of
non - small - cell lung cancer in Chinese
patients . -
pubmed
This paper reviews its role in the targeted treatment of
NSCLC in Chinese
patients . -
pubmed
A total of 20,922 participants ( 53 %
women ; mean age 58 + - 9 years ) were included of whom 1101 developed
heart failure during the follow up ( mean 12.5 + - 2.7 years , total person years 262,291 years ) . -
pubmed
Men experienced significant improvement in urinary flow rate , postvoid residual urine , and
OAB symptoms reported on the OABSS . -
pubmed
Of the 28/42
men with preoperative , clinically significant
OAB ( ie , OABSS & gt;= 8) , 25/28 reported a 54.2 % ( 0%-100 % ) median reduction in OABSS , with only 1 patient reporting worsening of symptoms following surgery . -
pubmed
Those
men with the highest preoperative OABSS experienced the greatest improvement in
OAB symptoms postoperatively . -
pubmed
However , the function of lncRNAs in
human gastric cancer remains largely unknown . -
pubmed
PURPOSE : To compare visual acuity ( VA ) , contrast sensitivity , stereopsis , and subjective visual performance of Acuvue Oasys for
Presbyopia ( AOP ) , Air Optix Aqua Multifocal ( AOMF ) , and Air Optix Aqua Single Vision ( AOSV ) lenses in
patients with
presbyopia . -
pubmed
Twenty
patients with mild
presbyopia ( add & lt;=+1.25 D ) and 22 with moderate / severe
presbyopia ( add & gt;=+1.50 D ) who wore lenses bilaterally for 1 h , with a minimum overnight washout period between the use of each lens . -
pubmed
CONCLUSIONS : Further development of multifocal lenses is required before significant advantages of multifocal lenses over single vision lens are observed in
patients with
presbyopia . -
pubmed
DT97 was evaluated in the
NCI-60 panel of
human cancer cell types and anticancer activity was greatest against MM ,
leukemia and
lymphoma cells . -
pubmed
Co - treatment with
DT97 and
bortezomib synergistically induced apoptosis in
MM patient cells and overcame
bortezomib - resistance . -
pubmed
Co - treatment with
bortezomib and
DT97 reduced the growth of
myeloma xenotransplants in
murine models and prolonged host survival . -
pubmed
Analysis of oral
yeast microflora in
patients with
oral squamous cell carcinoma . -
pubmed
BACKGROUND :
Oral squamous cell carcinoma (
OSCC ) is the most common form of
oral cancer , in this study , the association between
OSCC and oral
yeast carriage was investigated . -
pubmed
FINDINGS : 20
patients having
OSCC as well as 40
healthy controls were tested for the presence of yeasts in the oral cavity . -
pubmed
We found that the level of oral
yeast carriage was significantly higher in patients with
OSCC that was accompanied by a higher diversity of yeasts in the oral cavity of these patients . -
pubmed
BACKGROUND : The ability to identify high risk
head and neck cancer (
HNC )
patients with disseminated disease prior to presenting with clinically detectable metastases holds remarkable potential . -
pubmed
However , the clinical significance of
CTCs in
head and neck cancer patients has yet to be determined . -
pubmed
METHODS : The aim of this study was to screen advanced stage
HNC patients by the CellSearch platform and utilise two other epitope - independent approaches , ScreenCell ( microfiltration device ) and RosetteSep ( negative enrichment ) , to determine how a shift to such methodologies would enable CTC enrichment and detection . -
pubmed
BACKGROUND : The
human body has an extensive capacity to regenerate bone tissue after
trauma . -
pubmed
Therefore , the aim of the present study was to assess the pool and biological functions of
human mesenchymal stromal cells ( hMSCs ) isolated from different bone marrow locations of the lower limbs and to identify novel strategies to prime the cells prior to their use in
bone fracture healing . -
pubmed
White - nose syndrome is an
invasive bat disease caused by the fungus
Pseudogymnoascus destructans , which has killed more than six million bats in the last 7 years . -
pubmed
Our results suggest that bats in western North America caves possess novel bacterial microbiota with the potential to inhibit P. destructansIMPORTANCE This study reports the largest collection of actinobacteria from bats with activity against
Pseudogymnoascus destructans , the fungal causative agent of
white - nose syndrome . -
pubmed
These cells were inoculated in the mammary fat pad of female
severe compromised immunodeficient mice , which subsequently formed xenograft
tumors that metastasized to the lungs . -
pubmed
Our data was compared to several gene datasets of various subtypes , classes , and grades of
human breast cancers . -
pubmed
We demonstrated that the genes and pathways altered in the transgenic cell line and
metastatic animal models parallel many of the dysregulated gene pathways observed in
human breast cancers . -
pubmed
pylori - positive
dyspeptic patients were enrolled , either naive or with previous failure treatment . -
pubmed
They were mild in all cases except in four , who discontinued the study due to
diarrhea ( three
patients ) and diffuse
urticarial rush ( one patient ) . -
pubmed
One Health is an emerging concept that stresses the linkages between
human , animal , and environmental health , as well as the need for interdisciplinary communication and collaboration to address health issues including emerging
zoonotic diseases , climate change impacts , and the
human - animal bond . -
pubmed
Data support further development of
FXaI16L for
patients with acute
hemorrhagic conditions . -
pubmed
The safety profile , pharmacokinetics and pharmacodynamics observed in this clinical trial support the further development of
FXaI16L for hemostatic treatment in
individuals with
acute hemorrhagic conditions . -
pubmed
Clinical characteristics and surgical treatment of
spinal paraganglioma : A case series of 18
patients . -
pubmed
METHODS : The clinical and follow - up data of 18
patients who were diagnosed of
spinal paraganglioma and treated with surgeries in our hospitals from 2003 to 2014 were retrospectively analyzed . -
pubmed
RESULT : A total of fourteen
patients radiographed of
intra - spinal tumor underwent extra - capsular
tumor resection . -
pubmed
Of five
patients with obvious
vertebral bone damage , four cases underwent piecemeal resection , and the left one with sacral
tumor underwent en bloc
tumor excision . -
pubmed
METHODS : A retrospective analysis of all 58
patients with MRTK from Austria , Switzerland , and Germany treated in the framework of consecutive , prospective renal /
rhabdoid tumor studies SIOP9 / GPO , SIOP93 - 01 / GPOH ( where SIOP is International Society of Pediatric Oncology and GPOH is German Society of Pediatric Oncology and Hematology ) , SIOP2001 / GPOH , and European
Rhabdoid Tumor Registry from 1991 to 2014 . -
pubmed
Thirty - seven ( 64 % )
patients achieved a complete remission , 17 ( 29 % ) relapsed , 34 ( 59 % ) died of
disease progression , and two ( 3 % ) died of treatment - related complication . -
pubmed
CONCLUSION : Our retrospective analysis suggests comparable outcomes for
patients with and without HDSCT , if adjusted for early
disease progression . -
pubmed
Observations : An 81 - year - old
male presented with
decreased vision in the left eye due to a full - thickness
macular hole secondary to vitreomacular traction . -
pubmed
Tacrolimus and
Mycophenolate Mofetil as Second - Line Therapies for Pediatric
Patients with
Autoimmune Hepatitis . -
pubmed
BACKGROUND : We studied the efficacy and safety of
mycophenolate mofetil (
MMF ) and
tacrolimus as second - line therapy in pediatric
patients with
autoimmune hepatitis (
AIH ) who were intolerant or non - responders to standard therapy (
corticosteroid and
azathioprine ) . -
pubmed
CONCLUSIONS : Long - term therapy with
MMF or
tacrolimus was generally well tolerated by pediatric
patients with
AIH . -
pubmed
In vivo therapeutic efficacies of
gemcitabine and
rad001 alone and their combination were further evaluated using a xenograft
mouse model and a chemically induced orthotopic
cholangiocarcinoma rat model . -
pubmed
In a chemically induced
cholangiocarcinoma - afflicted
rat model , the
gemcitabine plus
rad001 treatment suppressed
tumor glycolysis as measured by
18F - fludeoxyglucose micro - positron emission tomography . -
pubmed
Elevated extracellular
potassium prior to muscle contraction reduces onset and steady - state exercise
hyperemia in
humans . -
pubmed
Persisters have been linked to recalcitrant
infections caused by numerous bacterial pathogens , including
Pseudomonas aeruginosa A classic example is the incurable
infection of the airways for patients with
cystic fibrosis . -
pubmed
However , less is known about
EBV 's interaction with T cells and its association with
T cell lymphoma . -
pubmed
Because , the co - presence of
EBV infection with
malaria is a well - known aetiology of
lymphoma ,
EBV - early RNA ( EBER ) transcripts were investigated in paraffin - embedded tissue samples and found to be positive in macrophage - like histiocytes . -
pubmed
This case emphasizes the clinical importance of
EBV monitoring in
T - LGL patients with skin involvement . -
pubmed
Postural Orthostatic Tachycardia in a
Patient with
Type 2 Diabetes with
Diabetic Neuropathy . -
pubmed
A 24 - year - old Japanese
man with
type 2 diabetes mellitus and
diabetic neuropathy was admitted to our ward to evaluate the cause of
orthostatic intolerance . -
pubmed
The relative
sympathetic hyperactivity in the present
patient with
diabetic neuropathy seemed to be related to
POTS . -
pubmed
STUDY OBJECTIVE : To evaluate the feasibility , effectiveness , and reproductive outcome of hysteroscopic management using the Hysteroscopy Endo Operative system ( HEOS ) in
patients with diffuse
uterine leiomyomatosis (
DUL ) . -
pubmed
Two
patients had mild
synechia after the first hysteroscopic surgery . -
pubmed
One
patient suffered a
miscarriage in the second trimester ( live birth rate , 75 % ) . -
pubmed
Importantly , treatment of adult
mice with the established disease also reduced
ICH . -
pubmed
Anti - proliferative activity of
Origanum vulgare inhibited lipogenesis and induced mitochondrial mediated apoptosis in
human stomach cancer cell lines . -
pubmed
In our present study , we have identified the bio - active principles of
oregano essential oil ( EO ) and evaluated its apoptotic effects against
human stomach cancer cell lines (
AGS ) . -
pubmed
The present study finds rationale to use the
oregano EO for
stomach cancer treatments in traditional medicinal practice . -
pubmed
Considering that
hepatoblastoma develops in infants and
children and
aflatoxin M1 (
AFM1 ) , the
aflatoxin B1 (
AFB1 ) hydroxylated metabolite , can be present in
mothers ' milk and in marketed milk products , in this study we decided to test the effects of
AFM1 on a
hepatoblastoma cell line (
HepG2 ) . -
pubmed
Recently , several studies have shown that morbidity and quality of life in adolescent and adult
patients with 21 -
OHD are impaired by
obesity ,
hypertension ,
diabetes mellitus ,
impaired glucose tolerance ,
dyslipidemia , and
osteoporosis . -
pubmed
The tagging single nucleotide polymorphisms were genotyped using the TaqMan Allelic Discrimination assay in a total of 468 subjects ( 265
KD patients and 203 controls ) . -
pubmed
Methodological questions regarding focused assessment sonography for
trauma comparison with computed tomography in
dogs . -
pubmed
However , the
patient subsequently developed
multiple organ failure and died in April 2018 , approximately 6 months after the initial discovery of the mass in his neck . -
pubmed
Purpose : For
chronic inflammatory demyelinating polyneuropathy (
CIDP )
patients , each branded intravenous immunoglobulin ( IVIG ) treatment differs in production processes , virus elimination , formulation , and composition . -
pubmed
Patients and methods : Two independent analytic teams retrospectively evaluated IVIG treatment - naive
patients with an ICD diagnosis code for
CIDP . -
pubmed
Chronic pain is a major health - care problem worldwide , affecting more than one out of five
adults in Europe . -
pubmed
A 64 - year - old
man with
gastrointestinal stromal tumor of the small intestine discontinued adjuvant
imatinib because of
interstitial pneumonia . -
pubmed
RESULTS : Cervical magnetic resonance imaging ( MRI ) revealed
spinal cord edema in 9
patients and suspected
hemorrhage or
contusion in 7 cases . -
pubmed
CASE REPORT A 76 - year - old male
patient with a 4 - year history of reducible left
inguinal hernia complained of
abdominal pain for 2 h before admission . -
pubmed
The present case report suggests that clinical and radiological awareness are very important for accurate diagnosis and management in
patients with reduction en - masse of an
inguinal hernia . -
pubmed
Frequency of MRI changes suggestive of
axial spondyloarthritis in the axial skeleton in a large population - based cohort of
individuals aged < 45 years . -
pubmed
Immune checkpoint inhibitors therapy in older
patients ( > = 70 years ) with
metastatic melanoma : a multicentre study . -
pubmed
Aim : To analyse the efficacy and safety of immunotherapy with checkpoint inhibitors in older
patients ( > = 70 years ) with
metastatic melanoma . -
pubmed
Neonates and immunosuppressed / immunocompromised pediatric
patients are at high risk of invasive
fungal diseases . -
pubmed
In all
patients , intra- and
postoperative complications as well as the overall treatment outcome were recorded . -
pubmed
Postoperative complications were found in 6
patients in group A and in one
patient in group B. Analyzing risk factors for these complications , the highest OR ( 6.72 with p = 0.085 in univariate analysis ; 12.81 with p = 0.052 in multivariate analysis ) was found for the type of procedure ( group A / group B ) . -
pubmed
All
patients had complete mucosal coverage without any signs of antiresorptive agent - related
osteonecrosis of the jaw at the final control examination 90 days postoperatively . -
pubmed
CONCLUSION : Based on the results of this study , the use of PRF can be recommended as a preventive measure in
patients requiring tooth extractions while being under antiresorptive therapy for
osteoporosis . -
pubmed
Chlorophenols ( CPs ) are known as a class of pollutants posing a great threat to the environment and
human health because of their
carcinogenesis and
teratogenesis , and thus exploring convenient and efficient methods for their detection and identification becomes particularly important . -
pubmed
Patients with
mucosal melanoma may be offered the same therapies recommended for
cutaneous melanoma . -
pubmed
Incidence of New Primary
Cutaneous Melanoma in
Patients With
Metastatic Melanoma Treated With Immune Checkpoint Inhibitors : A Single - Center Cohort Study . -
pubmed
Objective : To determine the incidence of new
CM in
patients treated with
ipilimumab ,
nivolumab , and/or pembrolizumab for
metastatic melanoma . -
pubmed
Design , Setting , and Participants : Single - center , retrospective , observational cohort study using an institutional database to identify
patients diagnosed with
melanoma at a tertiary care
cancer hospital in New York , New York . -
pubmed
Patients who developed a new
CM were more likely to have a family history of
melanoma ( 23.8 % vs 16.3 % , P = .02 ) . -
pubmed
Conclusions and Relevance :
Patients treated with ICI therapy for
metastatic melanoma remain at risk for the development of new
CM . -
pubmed
RESULTS : 326 studies were screened , and 30 studies reporting findings from 55,176
patients including 899 with
stroke were included . -
pubmed
The average age of
patients who suffered from
stroke as a complication of
COVID-19 was 65.5 ( Range : 40.4 - 76.4 years ) . -
pubmed
The average mortality of
stroke in COVID-19
patients was 31.76 % ( 95 % CI : 17.77 % to 47.31 % ) . -
pubmed
In COVID-19
patients ,
stroke was associated with older age , comorbidities , and severe illness . -
pubmed
Objectives : The paper presents the reconstructive options of the lower eyelid region in
patients who have benefited from the excision of
basal cell carcinomas . -
pubmed
Methods : The study was based on the clinical and evolutionary particularities analyzed in a series of cases , the
patients benefiting from excision and reconstruction for the treatment of
basal cell carcinomas located at the level of the orbital region . -
pubmed
The aesthetic results were strongly influenced by the stage of the
neoplasm , the final aspect being satisfactory for the
patients included in the study . -
pubmed
The resolution of
gastritis and
peptic ulcer appears to be linked with the eradication of
H pylori . -
pubmed
Consequently , strategies aiming at inhibition of the
cholesterol glucosylation process have the potential to attenuate the potency of
H pylori infection and abrogate
H pylori immune evasion capabilities . -
pubmed
In this work , we review the main roles of
cholesterol glucosylation in
H pylori and evaluate whether this mechanism can be targeted for the development of alternate methods for eradication of
H pylori infection . -
pubmed
We identified 92
patients who were diagnosed with
sIBM , according to the 2011 ENMC or Griggs et al criteria . -
pubmed
BACKGROUND :
5 - Hydroxy-4 - methoxycanthin-6 - one (
PQ - A ) is the main active compound in
Ramulus et Folium Picrasmae , a Chinese herbal medicine commonly used in
colitis treatment . -
pubmed
Less severe course of
COVID-19 is associated with elevated levels of antibodies against seasonal
human coronaviruses OC43 and
HKU1 (
HCoV OC43 ,
HCoV HKU1 ) . -
pubmed
However , in the
rats adrenalectomized on day 15 or 20 , the
body weights were lower than in control
rats . -
pubmed
A delay in the time at which vaginal opening and the first oestrus occurred was found in
rats adrenalectomized at 20 or 25 days of age ; however this delay was accompanied in these
rats by a retardation in the gain in
body weight . -
pubmed
[
Human pulmonary diffusing capacity in combined exposure to
hypokinesia and
hypoxia ] . -
pubmed
Seven
women in
spontaneous labor , were compared to 7
women in whom labor was induced . -
pubmed
The inhibitory effect of the combination of
antineoplaston A-10 injection with a small dose of
cis - diamminedichloroplatinum on cell and
tumor growth of
human hepatocellular carcinoma . -
pubmed
A
human hepatocellular carcinoma cell line (
KIM-1 ) was used for the cell growth and transplanted
tumor growth studies . -
pubmed
In the
tumor growth study , daily administration of
Antineoplaston A-10 Injection 75 mg with once a week administration of 20 micrograms of
CDDP for 5 weeks inhibited transplanted
tumor growth in
athymic mice after 33 days of treatment , while administration of 75 mg of A-10 Injection or 20 or 60 micrograms of
CDDP alone showed no significant inhibition of
tumor growth . -
pubmed
Patients ( pts ) with
essential hypertension normally exhibit a typical diurnal variation with a nocturnal blood - pressure ( BP ) decreased . -
pubmed
[ Functional activity of polymorphonuclear leukocytes in
isoprenaline - induced
cardiomyopathy in
rats ] . -
pubmed
The article studies the dynamics of changes of the parameters of the functional activity using chemiluminescent and turbidimetric methods as well as blood plasma myocardium and liver homogenates in
isoprenaline cardiomyopathy in
rats . -
pubmed
Mechanisms of pathogenesis of
isoprenaline - induced
cardiomyopathy in
rats is being discussed . -
pubmed
The bidirectional effects of
shock on
alcohol preference in
rats . -
pubmed
Rats that initially preferred
alcohol decreased
alcohol preference during
shock days , whereas ,
rats that initially avoided
alcohol increased
alcohol preference during
shock days . -
pubmed
[
Drug abuse and
HIV in the hospital ] . -
pubmed
In addition ,
HIV-1 PCR and
HIV-1 culture were compared in testing the PBMC of 59
HIV-1 antibody - positive and 20
HIV-1 antibody - negative
hemophiliacs . -
pubmed
In contrast , the sensitivities of serum
HIV-1 antigen testing in
AIDS patients and asymptomatic seropositive patients were 42 and 17 % , respectively . -
pubmed
Our ability to directly demonstrate
HIV-1 infection in all
HIV-1 antibody - positive individuals provides definitive support that
HIV-1 antibody positivity is associated with present
HIV-1 infection . -
pubmed
Conception : Retrospective analysis of
patients ( pts ) admitted either to UCIM or UTIC - AC with the diagnosis of
AMI receiving SK . -
pubmed
In contrast to
avian influenza virus genes ,
human influenza virus genes evolve rapidly under the selective pressure of antibody . -
pubmed
The changes in
histamine and
prostaglandins (
PGE2 and
PGF ) in carrageenan - induced acute
inflammation were studied in 6 day old air pouches in
mice . -
pubmed
Argon laser therapy of
endometriosis : a review of 92 consecutive
patients . -
pubmed
The conception rate , relief of
pain , and safety of argon laser photocoagulation of
endometriosis were evaluated in 92
patients . -
pubmed
The release and metabolism of endogenous
arachidonic acid ( AA ) in physiologically activated platelets obtained from 11 atopic
patients with
allergic rhinitis and/or
asthma was compared to that of sex- and age - matched nonatopic controls . -
pubmed
Mild hypnotics are often recommended for young
children with
sleep problems . -
pubmed
This study assesses the efficacy of
trimeprazine tartrate in 1 to 3 year old
children with persistent and severe
night waking in a double blind crossover trial with placebo . -
pubmed
Treatment outcome and complications in
patients treated for
malignant epidural spinal cord compression (
SCC ) . -
pubmed
Lipid synthesis (
14 C - acetate incorporation ) in the isolated
human sebaceous gland , the appendage - freed epidermis , the sebocyst (
steatocystoma ) and the wen ( keratinous
cyst of skin ) . -
pubmed
Unusual serological behavior of a
strain of
Cl . - pubmed
[ Acid - base equilibrium of the amniotic fluid in pregnant
women with
heart defects ] . -
pubmed
Disturbances of pulmonary function in
patients with
fat embolism . -
pubmed
In the 26
animals studied , proliferative
GN of variable severity was induced , with mild disease in 5
animals , moderate proliferation in 15 and crescentic GN in 6 . -
pubmed
Specific binding of
1,25 - dihydroxycholecalciferol in
human medullary thyroid carcinoma . -
pubmed
A specific
1,25 - dihydroxycholecalciferol - binding protein has been detected in high - salt cytosols prepared from
human medullary thyroid carcinomas . -
pubmed
The management of the
diabetic patient with
renal disease . -
pubmed
The case is presented of a 36 - year - old
woman with a plasma - cell
granuloma arising in the fourth ventricle . -
pubmed
Morphine sulfate inhibits bronchoconstriction in
subjects with mild
asthma whose responses are inhibited by
atropine . -
pubmed
To determine whether
morphine sulfate alters the bronchoconstrictive response to inhalation of distilled water , we gave 13
subjects with mild
asthma 0.15 mg / kg
morphine sulfate or normal saline intravenously , after which they inhaled increasing volumes of nebulized distilled water from an ultrasonic nebulizer . -
pubmed
In the majority of the
patients , subjective symptoms were noted :
fever ,
headache ,
chills ,
nausea ,
myalgias . -
pubmed
Leucopenia and
thrombopenia were seen in 11 out of 13
patients . -
pubmed
Activity of two phase I drugs ,
homoharringtonine and
tricyclic nucleotide , against surgical explants of
human tumors in the 6 - day subrenal capsule assay . -
pubmed
Clearance half - times were prolonged in
patients with
lupus erythematosus compared with those in normal controls ( p less than 0.0001 ) and longer in
patients with
renal disease than in those without ( p less than 0.025 ) . -
pubmed
When matched for nonrenal activity ,
patients with
nephritis had greater clearance dysfunction than their counterparts without
renal disease . -
pubmed
Tiaprofenic acid 200 mg three times a day was compared with
indomethacin 25 mg three times a day in 36
patients suffering from
osteoarthritis of the knee and hip . -
pubmed
Schistosoma mansoni : biochemical changes during early stages of the
infection . -
pubmed
Controversies surround the practice of prescribing
potassium for ambulatory
hypertensive patients who are being treated with diuretics . -
pubmed
A chart review was conducted in a family medicine group practice to examine habits of
potassium monitoring and supplement prescribing for
patients receiving diuretic therapy for control of
hypertension . -
pubmed
An 11.1 % incidence of
femoral osteolysis ( 30 cases in 28
patients ) was identified in a series of 271 primary total knee arthroplasties . -
pubmed
In the study population , statistically significant factors associated with
femoral osteolysis included male gender ( P & lt ; .05 ) , younger age ( P & lt ; .05 ) , increased
patient weight ( P & lt ; .05 ) , positive tibial
osteolysis ( P & lt ; .001 ) ,
osteoarthritis ( P & lt ; .07 ) , and length of time in situ ( P & lt ; .001 ) . -
pubmed
The influence of age on treatment choice and survival in 735
patients with
renal carcinoma . -
pubmed
OBJECTIVE : To determine whether age is related to treatment choice and survival in
patients with
renal carcinoma . -
pubmed
PATIENTS AND METHODS : In this retrospective study 735
patients with
renal carcinoma , diagnosed between 1982 and 1990 in one of the hospitals connected to the Rotterdam Cancer Registry , were evaluated with respect to treatment choice and survival . -
pubmed
RESULTS : Nephrectomy was performed less often in elderly
patients , both with and without distant
metastases . -
pubmed
For
patients with
tumours restricted to the kidney ( Robson stage 1 ) , corrected survival rates were 80 , 70 and 48 % respectively . -
pubmed
CONCLUSION : Treatment choice and outcome in
patients with
renal carcinoma were affected by age . -
pubmed
The antimutagenic activity
Angelica archangelica L. water and
alcohol extracts thio - tepa against
mutagenicity was investigated by the micronucleus test in
mouse bone marrow and peripheral blood cells . -
pubmed
Injury to
51Cr - labeled
bovine artery pulmonary endothelial ( BPAE ) cells was quantified by the release of
51Cr from
BPAE cells incubated for 18 h with
injury expressed as a cytotoxic index . -
pubmed
METHODS : A comprehensive staff follow - up program for all blood exposures with known patient sources was initiated in 1989 , consisting of patient follow - up by the Infection Control Department ( risk assessment for
hepatitis B virus [
HBV ] and [
HIV ] infection and obtaining of consent for
HIV testing ) and staff follow - up by the Occupational Health Department . -
pubmed
HIV and
HBV screening was obtained for 67.9 % and 87.6 % of patients assessed as at low risk and 82.3 % and 92.2 % of those assessed as at high risk for
infection , respectively . -
pubmed
Impact of
tumor extent and location on treatment outcome in
patients with stage III
non - small cell lung cancer treated with radiation therapy . -
pubmed
The results of treatment of 141
patients with stage III
non - small cell lung cancer (
NSCLC ) who received definitive radiation therapy at Gunma University Hospital between 1976 and 1989 were retrospectively analyzed . -
pubmed
As for
tumor location , the
patients with primary
tumors in the upper lobes or the superior segment of the lower lobes of the lung lived longer than those with primary
tumors at any other site ( P = 0.032 ) . -
pubmed
Patients with
epidermoid carcinoma had a higher survival rate at 5 years than those with other histologic types ( 14 % vs 3 % , P = 0.074 ) . -
pubmed
Among the
patients with stage III
NSCLC , those with stage IIIA epidermoid
carcinoma in the upper lobe or the superior segment of the lower lobe of the lung were considered to be the most favorable candidates for definitive radiation therapy . -
pubmed
We investigated how residual
tumour burden after cytoreductive surgery was related to the occurrence of
acute and delayed nausea and vomiting in 101
ovarian cancer patients receiving their first chemotherapy course . -
pubmed
Patients with large compared with minimal
TB had more delayed
emesis , especially on days 2 - 7 . -
pubmed
The aggravating effect associated with large residual
TB was more evident in
patients & gt ; or = 55 years . -
pubmed
During the second week after the chemotherapy the occurrence of
nausea was higher in
patients & gt ; or = 55 years than in those & lt ; 55 years . -
pubmed
This was seen primarily in
patients with large residual
TB . -
pubmed
The course of
spinal muscular atrophy (
SMA ) is not well established except for those
patients whose age of onset is before 6 months and who achieve only " sit with support " as their maximum function (
Werdnig - Hoffmann disease or
SMA I ) . -
pubmed
A microdialysis study in spontaneously
hypertensive rats . -
pubmed
Two groups of eight spontaneously
hypertensive ( SHR ) and normotensive
Wistar - Kyoto ( WKY ) rats , aged 14 to 16 weeks , were studied . -
pubmed
Both activities were present in the PF of
subjects with or without
endometriosis . -
pubmed
Our results demonstrate that although the
strains belonged to different clones of
V. - pubmed
Selective
hippocampal lesions yield nonspatial
memory impairments in
rhesus monkeys . -
pubmed
Monkeys with removals of medial temporal lobe ( MTL ) structures are widely recognized as valid models of
human global
anterograde amnesia , a
syndrome that arises consequent to damage to a finite set of brain structures situated in the medial temporal lobe and/or medial diencephalon . -
pubmed
However , a comparison of
memory deficits in
human and
nonhuman primates with
MTL damage has presented a long - standing puzzle . -
pubmed
Whereas
amnesic patients are impaired in learning object discrimination problems ,
monkeys with
MTL damage are typically not . -
pubmed
If this analysis is correct ,
monkeys with
MTL damage might be disadvantaged in learning to discriminate similar objects presented in different contexts . -
pubmed
Monkeys with
hippocampal lesions were impaired relative to controls in learning object discrimination problems of this type . -
pubmed
These findings strongly support the idea that the difference in the effect on object memory of
MTL damage in
human and nonhuman
primates is due to a difference in the opportunity to employ contextual cues rather than to a difference in the organization of memory . -
pubmed
One
patient was a 29 - year - old male who complained of posteromedial radiating
knee pain . -
pubmed
The schedule is active in
patients with heavily pre - treated
breast cancer , with responses in up to 53 % ( overall 29 % ) . -
pubmed
At the Royal Marsden Hospital we have evaluated infusional 5 - FU 200 mg / m2 per day for up to 6 months in combination with 3 - weekly bolus
epirubicin ( E ) 60 mg / m2 and
cisplatin ( C ) 60 mg / m2 ( infusional ECF ) as pre - operative / neo - adjuvant treatment in 123
patients with operable
breast cancer greater than 3 cm ( median 6 cm ) , initially in a phase II study of 50
patients and subsequently as part of a randomised phase III trial . -
pubmed
These trials will determine whether encouraging phase II activity with continuous infusional chemotherapy translates eventually into real survival benefit for
patients with early
breast cancer . -
pubmed
OBJECTIVE : To study the
injury factors , pathogenic process and clinical features of delay two - phase
multiple organ dysfunction syndrome (
MODS ) in severe burned
patients and to replicate a standardized
animal model that would accurately imitate the clinical features of
MODS . -
pubmed
METHODS : Forty - five
human patients with
burn size larger than 30 % total body surface area ( TBSA ) were analyzed . -
pubmed
Thirty - two
goats were randomly divided into three groups : 1 )
hemorrhagic shock ( group H , n = 6 ) ; 2 )
endotoxemia ( group E , n = 6 ) ; and 3 )
hemorrhagic shock plus
endotoxemia ( group M , n = 20 ) . -
pubmed
Two
patients with
burn extent reaching 100 % TBSA survived with only mild
acute respiratory distress syndrome (
ARDS ) and
renal dysfunction after comprehensive treatment of
burn shock , including adequate fluid resuscitation , drugs to remove
oxygen free radicals , rapid restoration of pHi , and early extensive excision of
burn eschars . -
pubmed
CONCLUSION : Both in
human patients or animal experimentation , the typical delay two - phase
MODS is shown to be produced by two successive insults in the forms of
hypovolemic shock and
sepsis . -
pubmed
The purpose of this study was to examine whether
vitamin E supplementation in
humans would attenuate an increase of serum enzymes as an indirect marker of
muscle damage following a sudden large increase in the running distance in a 6 - day running training or not . -
pubmed
Styrene epoxidation of the
strain PS-1206 was studied in different reaction time . -
pubmed
Conversion was required in three
patients secondary to
bleeding or anatomical anomalies . -
pubmed
METHODS : The
mouse model of live
fibrosis was established with the application of intragastric installations of
carbon tetrachloride once every three days ; scanning electron microscope and computer image processing were used to detect the area and the distributive density of the peritoneal lymphatic stomata ; and the concentrations and
NO in the serum were measured and analyzed in the experiment . -
pubmed
PAGOD syndrome : eighth case and comparison to
animal models of
congenital vitamin A deficiency . -
pubmed
The condition may resemble the malformation complex associated with
developmental deficiency of
vitamin A or
retinoic acid , as described in
animal models . -
pubmed
Affected
children may suffer profound
developmental and cognitive impairment from exposure to high levels of
BCAA and their associated
neurotoxic metabolites . -
pubmed
This approach results in a 75 % reduction of systemic toxin levels within 3 h. When compared to other reported modalities of therapy for symptomatic
neonates with
MSUD , this approach appears to be most efficacious . -
pubmed
Use of
cattle farm resources by badgers (
Meles meles ) and risk of
bovine tuberculosis (
Mycobacterium bovis ) transmission to
cattle . -
pubmed
We conclude that exploitation by badgers of resources provided by
cattle farms constitutes a potentially important mechanism for
tuberculosis transmission from badgers to
cattle . -
pubmed
Assessment of cell type specific gene transfer of
polyoma virus like particles presenting a
tumor specific antibody Fv fragment . -
pubmed
Cyanovirin - N ( CV - N ) is under development as a topical ( vaginal or rectal ) microbicide to prevent sexual transmission of
human immunodeficiency virus (
HIV ) , and an economically feasible means for very large - scale production of the protein is an urgent priority . -
pubmed
Chlamydia pneumoniae DNA has been detected in at least 40 % of all major arteries affected by
atherosclerosis , but several other microorganisms have also been detected . -
pubmed
These findings may have implications for antibiotic prophylaxis of
coronary heart disease if directed solely at
Chlamydia pneumoniae . -
pubmed
Neonatal lesions in the amygdala or ventral hippocampus disrupt prepulse inhibition of the acoustic startle response ; implications for an
animal model of
neurodevelopmental disorders like
schizophrenia . -
pubmed
Schizophrenic patients show deficits in prepulse inhibition of the acoustic startle response . -
pubmed
The
animal model of
neurodevelopmental disorders such as
schizophrenia , as purported in earlier reports and the present study , is based on the assumption that damage to brain structures early in life ( on day 7 ) disrupts brain maturation of structures connected to the damaged areas , measurable by behavioural changes , whereas similar damage later in life ( on day 21 ) does not result in these behavioural changes . -
pubmed
The effects of early postnatal lesions on prepulse inhibition and locomotor activity are in support of the
animal model of
neurodevelopmental disorders like
schizophrenia . -
pubmed
Renal transplantation offers the best renal replacement therapy for most
children with
end stage renal disease improving their potential for growth and nutrition , neurodevelopment and quality of life . -
pubmed
Advances in organ retrieval and preservation , improved surgical techniques , newer immunosuppressive drugs and prevention and treatment of
infections have significantly improved
patient and graft survival . -
pubmed
Of a study group of 1286
patients who were referred in early chronic - phase
CML between 1981 - 2001 and who received therapies other than allogeneic SCT , 1093
patients had regular follow - up at the study institution . -
pubmed
Patients with sudden blastic - phase disease were found to have more often low - risk features at the time of presentation , including low incidences of blasts and
thrombocytosis . -
pubmed
The
strains tested had a negative impact on the survival of Eurytemora , as well as on the embryonic development and hatching regime of the
Baltic herring . -
pubmed
[ Review of Polish literature on
human brucellosis from 1928 to 1958 ] . -
pubmed
[ Development of a
mouse mammary adenocarcinoma transplanted into a pneumoderma ] . -
pubmed
The new continuous
leukemia cell line
MUTZ-11 was established in 1994 from the peripheral blood of a 60 - year - old
woman with
acute myeloid leukemia (
AML ) M4 ( following 2 years with
myelodysplastic syndromes ) . -
pubmed
The authors tested 11
patients with
developmental prosopagnosia using this test , and a majority scored in the normal range . -
pubmed
Government cleared in disabled
man 's
AIDS - related
death . -
pubmed
A
hypercholesterolemic patient medicated with
cerivastatin for 22 days resulted in acute
rhabdomyolysis . -
pubmed
OBJECTIVE : In the
7,12 - dimethylbenz [ a ] anthracene (
DMBA ) model of
rat mammary
carcinogenesis , microvascular density and angiogenic potential increase with progression from normal to invasive disease , but the mechanisms involved are unknown . -
pubmed
Efficacy and safety of
lanthanum carbonate for reduction of serum
phosphorus in
patients with
chronic renal failure receiving hemodialysis . -
pubmed
BACKGROUND :
Lanthanum carbonate is a highly effective
phosphate binder with significant potential as a treatment for
hyperphosphatemia in
patients with
end - stage renal disease (
ESRD ) . -
pubmed
CONCLUSION :
Lanthanum carbonate is an effective and well - tolerated agent for the short - term treatment of
hyperphosphatemia in
patients with
ESRD . -
pubmed
Streptococcus pneumoniae is the most important bacterial cause of
pneumonia and
meningitis among adults world wide . -
pubmed
It is a particularly common cause of these
infections and also
bacteraemia among
HIV infected adults with rates of disease increasing to more than 100 times the normal as
HIV infection progresses to
AIDS . -
pubmed
Factors underlying susceptibility to
pneumococcal infection in
HIV infected adults are then reviewed , along with the effectiveness of current vaccines . -
pubmed
Finally , novel approaches that will be needed to combat
PD in
HIV afflicted parts of the world are suggested . -
pubmed
To investigate the relationship between
ischemia - reperfusion and apoptosis in the uterus , we analyzed a
uterine ischemia - reperfusion model using BDF1 and C57BL/6
mice . -
pubmed
Our
mouse model could be suitable for investigating
ischemia - related
uterine injury in
humans , particularly in menstruation . -
pubmed
Neonatal
HBV vaccination prevents
adult cancer . -
pubmed
In the prevention of acquired
rubella ,
varicella ,
HBV ,
influenza ,
poliovirus ,
measles and
hepatitis A , one should mention the added bonus of preventing secondary cases by preventing transmission from infants and children to other children and adults . -
pubmed
Preventing paediatric
HSV ,
HBV and
HIV infection in females may even be preventing subsequent transmission to future generations . -
pubmed
As a powerful predictor of future
fracture risk , the identification of
vertebral fracture helps target
individuals who will benefit from anti -
fracture therapy . -
pubmed
[ Late course three - dimensional conformal radiotherapy in
patients with stage III
non - small cell lung cancer ] . -
pubmed
OBJECTIVE : To evaluate the therapeutic efficacy and radiation complications of late course three - dimensional conformal radiotherapy ( 3DCRT ) in
patients with stage III
non - small cell lung cancer (
NSCLC ) . -
pubmed
METHODS : Eighty - six
patients with stage III
NSCLC were randomly divided into group A ( n=42 ) receiving conventional radiotherapy at the total dose of 66 to 70 Gy in 33 to 35 fractions completed in 6 to 7 weeks and group B ( n=44 ) with late course 3DCRT at the dose of 24 - 30 Gy in 6 fractions ( 400 - 500 cGy per fraction every other day ) after 40 Gy conventional radiotherapy , completed in 5 to 6 weeks . -
pubmed
CONCLUSION : Late course 3DCRT produces better therapeutic effects than conventional radiotherapy in
patients with stage III
NSCLC . -
pubmed
We describe our experience in the case of a 71 - year - old
woman with a
posterior fossa DAVF who presented with sudden onset
headache , collapse and
neurological deficit secondary to a
subarachnoid haemorrhage . -
pubmed
Studies in the biochemistry of micro - organisms :
Itaconic acid , a metabolic product of a
strain of
Aspergillus terreus Thom . -
pubmed
METHODS : We investigated the influence of
NO on the proliferation , cell cycle , apoptosis , and differentiation of immortalized
human oral keratinocytes (
IHOK ) and primary
oral cancer cells (
HN4 ) using the
3 -( 4,5 - dimethylthiazol-2 - yl )- 2,5 - diphenyltetrazolium bromide (
MTT ) assay ,
sulforhodamine B (
SRB ) assay , flow cytometry , nuclear DNA staining , and Western blotting . -
pubmed
Extracts of
Aesculus hippocastanum (
horse chestnut ) seed have been used in the treatment of
chronic venous insufficiency ,
edema , and
hemorrhoids . -
pubmed
In addition , we analyzed the cell growth inhibitory effects and the induction of apoptosis in
HT-29 human colon cancer cell line . -
pubmed
To understand the growth inhibitory effects ,
HT-29 human colon carcinoma cell lines were treated with various concentrations of
beta - escin and analyzed by flow cytometry for apoptosis and cell cycle progression . -
pubmed
[ Effects of Siwu decoction on bone marrow protein expression of
blood deficiency mice induced by
cyclophosphamide ] . -
pubmed
OBJECTIVE : To study the effects of Siwu decoction on protein expression of
blood deficiency mice induced by
cyclophosphamide (
CIX ) and discuss the possible molecular mechanism on blood enriching function of Siwu decoction . -
pubmed
METHOD :
Blood deficiency mice were established by injecting ip with 250 mg x kg(-1 )
CTX . -
pubmed
RESULT : Siwu decoction could restore the changes of 12 up - regulated and 3 down - regulated proteins in bone marrow of
blood deficiency mice induced by
cyclosphosphamide . -
pubmed
OBJECTIVES : To evaluate the changes in voiding symptoms in female
patients with
stress urinary incontinence (
SUI ) undergoing transvaginal sling techniques over a five - year period in the Department of Urology at the University Hospital of Albacete . -
pubmed
METHODS : Between November 2001 and December 2005 126
patients with
SUI ( mean age 57.09 years ; 36 - 78 ) underwent transvaginal sling techniques ( Sling in Fast , TVK TOT ) . -
pubmed
The number of
urinary leak episodes per day diminished in 114
patients ( 90.5 % ) with a mean decrease of 9.65 episodes ( 95 % CI : 8.56 - 10.79 ) ( p & lt ; 0.0001 ) . -
pubmed
Hcy - thiolactone levels are elevated in
hyperhomocysteinemic humans and
mice . -
pubmed
OBJECTIVE : To describe speech production longitudinally in a group of
children with
unilateral cleft lip and palate (
UCLP ) . -
pubmed
PARTICIPANTS : Twenty consecutive
children with
UCLP and nine age - matched
children without
clefts in a comparison group . -
pubmed
The most active compounds were
N -[ 2 -( 4 - chlorophenoxymethyl )- benzoyl ]- N '-( 2,6 - dichlorophenyl )- thiourea ( 5 g ) and
N -[ 2 -( 4 - chlorophenoxymethyl )- benzoyl ]- N '-( 4 - bromophenyl )- thiourea ( 5h ) , which showed a broad spectrum of antimicrobial activity against
enterobacterial strains (
E. - pubmed
In this report , we present a case of a
patient with severe
mitral stenosis that underwent successful video - assisted minimally invasive mitral valve replacement . -
pubmed
Alpha - ZrPN were applied for the analysis of tryptic digests of
mouse liver and
leukemia cell phosphoproteomes and succeeded in identifying 158 phosphopeptides ( 209 phosphorylation sites ) from 101 phosphoproteins in
mouse liver lysate and 78 phosphopeptides ( 104 phosphorylation sites ) from 59 phosphoproteins in
leukemia cell extract . -
pubmed
This review will highlight the developments in cellular medicine that may soon permit interventional
pain management physicians to treat a much wider variety of clinical conditions and highlight an interventional case study using these technologies OBJECTIVE : To determine if isolated and expanded
human autologous mesenchymal stem cells could effectively regenerate cartilage and meniscal tissue when percutaneously injected into knees . -
pubmed
CONCLUSION : The described process of autologous mesenchymal stem cell culture and percutaneous injection into a knee with symptomatic and radiographic
degenerative joint disease resulted in significant cartilage growth , decreased
pain and increased joint mobility in this
patient . -
pubmed
We compared the surgical outcomes of recent
patients with cerebellopontine angle (
CPA )
epidermoids treated with advanced surgical tools with those of
patients treated in earlier series . -
pubmed
From November 2000 to June 2004 , we treated 12
patients with
epidermoid tumors . -
pubmed
Total removal was achieved in 7 of the 10
patients with unilateral CPA
epidermoids . -
pubmed
Clinical criteria are persistent
erythematous macules and
annular lesions with a red - brown edge and a central
hypopigmentation usually found on the flanks and groins of
children and adolescents . -
pubmed
RESULTS : Significant
left main stem disease was present in 54
patients ( 6.8 % ) . -
pubmed
71
patients ( 9 % ) had at least one of the events comprised in the combined study end - point (
unstable angina ,
myocardial infarction (
AMI ) and
cardiac death ) . -
pubmed
RESULTS : The rate of major adverse cardiac events including
death ,
myocardial infarction , and target vessel revascularization in
patients excluded from randomization ( n = 343 ) was significantly higher at 30 days ( 10.2 % vs. 1.6 % ) , 6 months ( 17.5 % vs. 5.6 % ) , and 12 months ( 24.5 % vs. 9 % ) compared with randomized
patients ( n = 1,005 ; P & lt ; 0.0001 ) . -
pubmed
[
Pleuropulmonary blastoma in an adult
women with
pleurorrhea as the major clinical manifestation : report of a case ] . -
pubmed
OBJECTIVE :
Pleuropulmonary blastoma (
PPB ) is a rare
dysontogenetic neoplasm in
children and has been recognized as a distinct clinicopathological entity different from the ordinary
pulmonary blastoma of adulthood . -
pubmed
A new yeast species ,
Vanderwaltozyma verrucispora , is proposed in this study based on two
strains isolated from partially decayed leaves in Japan and one
strain from soil in Taiwan . -
pubmed
CONCLUSION : The results of this meta - analysis suggest an improvement of survival in the
patients treated with the targeted therapies approved for
pulmonary arterial hypertension . -
pubmed
Depending on the
patient 's cooperation and the
fracture stability , a lower - leg cast may additionally be applied . -
pubmed
Fifty - six pregnant
women with
gestational diabetes mellitus (
GDM ) and 42 normal
glucose tolerant ( NGT ) pregnant
women between 26 and 36 gestational weeks were included in the study prospectively . -
pubmed
BACKGROUND & amp ; AIMS :
Epstein - Barr virus (
EBV ) has been causally associated with
cancer ; some gastric
carcinomas have a monoclonal
EBV genome in every
cancer cell , indicating that they arose from a single infected progenitor cell . -
pubmed
METHODS : We conducted a meta - analysis of 70 studies including 15,952 cases of
gastric cancer assessed by in situ hybridization for
EBV - encoded small RNA . -
pubmed
RESULTS : The pooled prevalence estimate of
EBV positivity was 8.7 % ( 95 % confidence interval [ CI ] : 7.5%-10.0 % ) overall , with a 2 - fold difference by sex : 11.1 % ( 95 % CI : 8.7%-14.1 % ) of
gastric cancer cases in males vs 5.2 % ( 95 % CI : 3.6%-7.4 % ) of cases in females . -
pubmed
EBV prevalence was 4 times higher ( 35.1 % ) for
tumors in postsurgical gastric stump / remnants . -
pubmed
Over 90 % of
lymphoepithelioma - like
carcinomas were
EBV positive , but only 15 studies reported any cases of this type ; prevalence did not significantly differ between the more common diffuse ( 9.5 % ) [ corrected ] and intestinal ( 7.6 % ) [ corrected ] histologies . -
pubmed
Epidemiologic studies comparing
EBV - positive and -negative
gastric cancers are warranted to investigate
EBV 's role in gastric
carcinogenesis . -
pubmed
Osteoporosis in
women with
breast cancer and its effect on quality of life : a pilot study . -
pubmed
PURPOSE : The primary aim of this study was to evaluate the risk of
osteoporosis (
OP ) in
patients who had received adjuvant chemotherapy for
breast cancer . -
pubmed
PATIENTS AND METHODS : Twenty - six
patients with
breast cancer and 21 healthy controls were recruited into the study . -
pubmed
All
breast cancer patients were treated with 6 cycles of adjuvant chemotherapy . -
pubmed
The most affected domain of the SF-36 in
patients with
breast cancer was the physical role . -
pubmed
OP should be investigated during follow - up in order to improve the quality of life of the surviving
breast cancer patients . -
pubmed
RESULTS : The study population consisted of 40
rheumatoid arthritis (
RA ) , 34
ankylosing spondylitis (
AS ) , 9
juvenile rheumatoid arthritis (
JRA ) , and 3 other
patients . -
pubmed
Investigations of naturally occurring mutations , such as the deletional thalassaemias and
hereditary persistence of fetal haemoglobins (
HPFHs ) , have brought many insights into
human globin switching , but limited data have been reported so far . -
pubmed
CONCLUSIONS : Time to first detectable uPSA identifies
men with low - risk
recurrence prostate cancer . -
pubmed
METHODS : We prospectively evaluated the diagnostic efficacy of the cell block ( CB ) method and that of smear cytology using tissue samples obtained in the same needle pass at EUS - FNA in 33
patients with
pancreatic tumors ,
abdominal tumors or swollen lymph nodes . -
pubmed
DJD - associated
pain in
cats : what can we do to promote
patient comfort ? -
pubmed
PRACTICAL RELEVANCE :
Degenerative joint disease (
DJD ) has a high prevalence in domestic
cats and can be associated with
pain . -
pubmed
AUDIENCE : All practitioners are faced with
cats that are
mobility impaired due to
DJD - associated
pain . -
pubmed
PATIENT GROUP :
Cats of all ages and
breeds , and either sex , can experience
DJD - associated discomfort . -
pubmed
CLINICAL CHALLENGES : Recognizing
DJD and assessing DJD - associated
pain in
cats is a challenge . -
pubmed
Current understanding of the etiology of
feline DJD and the mechanisms of
DJD - associated
pain is incomplete , making the rational choice of treatments a further challenge . -
pubmed
EVIDENCE BASE : Evidence is emerging on the prevalence of
feline DJD , and on how to assess the associated
pain and
mobility impairment . -
pubmed
There is a lack of information on the etiology of
feline DJD and a relative lack of data on the efficacy of putative treatments . -
pubmed
Of 116
patients , 69 % had optimal follow - up of
MGUS . -
pubmed
High - risk
MGUS patients ( & gt;= 1.5 g / dL and/or non - IgG MGUS ) were more likely to be optimally followed ( 81 % vs 64 % ) , and be diagnosed with
MM secondary to serial follow - up testing ( 21 % vs 7 % ) . -
pubmed
Future studies are needed to replicate and expand our findings and to determine the optimal frequency of monitoring in higher - risk
MGUS patients . -
pubmed
In many
patients , no treatment is ever necessary -- because
IHs are well known for their natural history of spontaneous involution . -
pubmed
Primary
spinal cord oligodendroglial tumor is very rare , and in only one
patient with
spinal cord oligodendroglioma has a deletion of chromosome 1p/19q been reported . -
pubmed
We present the case of an 18 - year - old
girl , who had one - year
lower back pain and one - month lower limb
weakness . -
pubmed
After treatment with
temozolomide for six months , the
patient had a remarkable improvement of her lower limb symptoms , and complete imaging regression of the residual
tumor showed no evidence of
recurrence at any other sites . -
pubmed
It is also the first case of the
patient with recurrent intramedullary
anaplastic oligodendroglioma who had a significant clinical improvement and complete imaging remission after subtotal resection then treatment with
temozolomide chemotherapy . -
pubmed
To describe uncommon association between central
retinal artery obstruction and dominant
macular drusen in two young female
patients . -
pubmed
Second
patient , a 34 - year - old female with a previous history of right central
retinal artery obstruction diagnosed elsewhere . -
pubmed
Antenatal
nicotine induces heightened oxidative stress and
vascular dysfunction in
rat offspring . -
pubmed
Outcome and predictors of treatment failure in total
hip / knee prosthetic joint infections due to
Staphylococcus aureus . -
pubmed
BACKGROUND : Variables associated with the outcome of patients treated for
prosthetic joint infections (
PJIs ) due to
Staphylococcus aureus are not well known . -
pubmed
METHODS : The medical records of
patients treated surgically for total
hip or knee prosthesis infection due to
S. - pubmed
aureus ( MRSA)-related
PJIs were not associated with worse outcome , compared with
methicillin - susceptible
S. - pubmed
CONCLUSIONS : The results of the present study suggest that the ASA score significantly affects the outcome of patients treated for total
hip and knee prosthetic infections due to
MSSA or
MRSA and that
rifampin combination therapy is associated with a better outcome for these patients when compared with other antibiotic regimens . -
pubmed
RESULTS : Pancreatic beta cells from Zucker fa / fa
rats and
obese individuals were found to be hyper - responsive to
glucose . -
pubmed
In 2 elderly
patients ( 1 % ) , a minor
dural injury with a
cerebrospinal fluid leak was controlled during the operation with temporalis fascia grafting . -
pubmed
In 1
patient ( 0.5 % ) , a
subdural hematoma was observed after bipolar cauterization of a prominent diploic vein . -
pubmed
We found that all three
strains of
T. - pubmed
METHODS : The clinical and outcome data of all advanced
ovarian , primary peritoneal and tubal carcinoma patients who after diagnosis had neoadjuvant chemotherapy and underwent interval debulking during the period 2000 - 2010 , were abstracted . -
pubmed
OBJECTIVE : This study was carried out between June - December 2008 to determine the prevalence of
toxoplasmosis in Pirlak
sheep in the Suhut district of Afyonkarahisar . -
pubmed
Greater physician awareness about these potential
infections is important to optimize
patient outcomes through early recognition and potential preventive strategies . -
pubmed
Mild - to - moderate
alveolitis was observed in the histopathological test of lungs from GSEI and
EPEV virus - infected
mice . -
pubmed
Tooth agenesis is one of the most common
developmental disorders in
humans . -
pubmed
We conducted a single - center retrospective study in
patients with
lymphoma and
myeloma treated at Brest Hospital to assess the cost reductions related to and the efficiency and safety of
filgrastim biosimilars . -
pubmed
We identified 65
patients with
lymphoma or
myeloma treated with
filgrastim biosimilars for ASCT and compared 19 parameters of these
patients , including BM recovery , side effects ,
infectious complications and treatment costs , with published historical data on a cohort of 50
patients treated with classic
filgrastim . -
pubmed
PATIENTS :
Children with
clinical deterioration , defined as
cardiopulmonary arrest , acute
respiratory compromise , or urgent intensive care unit transfer while hospitalized on pediatric wards ( n = 141 ) . -
pubmed
Physical predictors for moderate to severe
obstructive sleep apnea in snoring
patients . -
pubmed
PURPOSE : This study aimed to identify physical findings that may predict the presence of moderate to severe
obstructive sleep apnea (
OSA ) in snoring
patients . -
pubmed
METHODS : A total of 283
subjects ( 165
males and 118
females ) were recruited , including 217
OSA patients and 66
patients with
apnea -
hypopnea index ( AHI)<5 as a control group , diagnosed by level-1 polysomnography . -
pubmed
Arsenic trioxide (
ATO ) is being successfully used as a first and second line therapy for the treatment of
patients with
acute promyelocytic leukemia . -
pubmed
Results indicated that pre - training or pre - test intra - CA1 administration of
scopolamine ( 1.5 and 3 mug /
rat ) dose - dependently reduced the step - through latency , showing an
amnestic response . -
pubmed
The pre - training
scopolamine - induced
amnesia ( 3 mug /
rat ) was reversed by the pre - test administration of
scopolamine , indicating a state - dependent effect . -
pubmed
Pneumothorax occurred in 3.1 % of
patients , requiring chest tube drainage in 1.6 % of these cases . -
pubmed
Among them is the
tumor differentially expressed ( TDE ) protein family , which shows no homologue to any other protein families and is unique to
eukaryotes . -
pubmed
Goserelin fosters bone elongation but does not prevent
ovarian damage in
cyclophosphamide - treated prepubertal
mice . -
pubmed
ANIMAL(S ): C57BL/6J
mouse strain . -
pubmed
, 8708 DALYs / year for
hepatitis B virus and 740 DALYs / year for
measles virus . -
pubmed
METHODS : In all , 87 unselected consecutive hospitalizations due to
AECOPD in 61
subjects and a total of 190 consecutive
subjects with stable
COPD were recruited . -
pubmed
Only 5.6 % of
AECOPD subjects were associated with
systolic dysfunction defined as a left ventricular ejection fraction ( LVEF ) & lt;50 % ; a further 7.4 % were considered to have impaired relaxation defined as an E / A wave velocity ratio & lt;0.8 and a deceleration time of E & gt;240 ms . -
pubmed
Mycoplasma genitalium is an emerging sexually transmitted pathogen associated with
reproductive tract disease in men and women , and it can persist for months to years despite the development of a robust antibody response . -
pubmed
The histocompatibility efficacy of these nerve guide scaffolds was tested in a
rat model for
peripheral nerve injury treatment . -
pubmed
Based on the compelling evidence of the randomized Placement of Aortic transcatheter valves ( PARTNER ) A and B cohort , TAVI is now considered standard of care for extreme risk and inoperable
patients and is an alternative to surgery for high - risk patients with symptomatic
aortic stenosis . -
pubmed
This case shows that
Hermansky - Pudlak syndrome should be considered in the differential diagnosis of a
patient presenting with
bleeding diathesis , when the clinical presentation also includes
oculocutaneous albinism and
visual problems . -
pubmed
We shortly introduce these channels , summarize nomenclature and chromosomal location of the 28
mammalian Trp genes , and list the available
Trp - deficient mouse lines . -
pubmed
Different effects of
bifeprunox ,
aripiprazole , and
haloperidol on body
weight gain , food and water intake , and locomotor activity in
rats . -
pubmed
In this study , the changes in elemental composition that occurred in the hippocampal formation in the electrical kindling model of
seizures were examined to determine the mechanisms responsible for the phenomenon of kindling and spontaneous
seizure activity that may occur in this
animal model . -
pubmed
MATERIALS & amp ; METHODS : Ex vivo biochemical experiments with
human platelets and exosomes , and
FeCl3 -induced
murine carotid artery thrombosis . -
pubmed
Injected exosomes inhibited occlusive
thrombosis in
FeCl3 -damaged
murine carotid arteries . -
pubmed
Control platelets infused into irradiated ,
thrombocytopenic mice reconstituted
thrombosis in damaged carotid arteries , but failed to do so after prior ex vivo incubation with exosomes . -
pubmed
INTRODUCTION : We evaluated the characteristics of
thyroid carcinoma in geriatric
patients and outcomes after a 10 - years follow - up . -
pubmed
METHODS : Comparative retrospective study on a group of 31 geriatric
patients and one of 224 non - geriatric , who underwent surgery for
thyroid carcinoma in the period 1998 - 2003 . -
pubmed
We compared with Fisher 's exact test : histology , multifocality ,
tumor size , lymph - node
metastasis , distant
metastasis , persistence /
recurrence and mortality , including and excluding
anaplastic carcinomas , in a subgroup of 26 geriatric
patients and another of 223 non - geriatric
patients . -
pubmed
DISCUSSION :
Thyroid carcinoma is more aggressive in geriatric
patients . -
pubmed
CONCLUSION : It would be useful to undertake randomized prospective studies on a large cohort of
patients to determine the most effective therapy for geriatric
patients suffering from
thyroid carcinoma . -
pubmed
These studies enrolled mostly treatment - resistant
depression patients , who received daily stimulation sessions on the left dorsolateral prefrontal cortex . -
pubmed
Abortion and
foetal lesions induced by
Neospora caninum in experimentally infected
water buffalos (
Bubalus bubalis ) . -
pubmed
It has been postulated that
buffalo may be resistant to abortion caused by
neosporosis , because of high serological prevalences found in
buffalo herds from different localities , with no description of
Neospora caninum - related abortion . -
pubmed
Recent studies have demonstrated the potential impact of
neosporosis in pregnant water buffalo
cows . -
pubmed
In this work , three pregnant
buffalo cows were experimentally infected with Nc-1
strain of
N. - pubmed
Here , we report a case of this uncommon sub type of
ameloblastoma in a young female
patient presenting as an extensive lesion in mandibular ramus area . -
pubmed
Patient underwent segmental mandibulectomy and histological examination of excisional specimen revealed features of
ameloblastoma with abundant keratinization leading to a diagnosis of
keratoameloblastoma . -
pubmed
We reviewed outcomes for 84
patients treated with
clofarabine for relapsed or refractory
AML or
MDS , either with
clofarabine as monotherapy ( n=19 ) or in combination with
cytarabine ( n=65 ) . -
pubmed
We describe clinical and muscle biopsy findings of a
patient with
sarcoidosis and
inclusion body myositis . -
pubmed
A 66 - year - old
man presented with a 6 - year history of progressive , asymmetrical and selective
weakness of the quadriceps , biceps and finger flexor muscles ; he had a remote history of
pulmonary sarcoidosis . -
pubmed
INTERVENTIONS :
Patients were organized by date of
dysplasia diagnosis , divided into 2 groups ( group 1 , January 1 , 1993 , through December 31 , 2002 ; group 2 , January 1 , 2003 , through December 31 , 2012 ) , and compared against one another . -
pubmed
Fish oil , which contains
omega-3 fatty acids mainly in the form of
triglycerides , has benefits for reducing
breast cancer risk , similar to
tamoxifen action . -
pubmed
METHODS : Clinical data of 316 surgical
GBC patients were analyzed retrospectively , and preoperative serum platelet and lymphocyte counts were used to calculate the PLR . -
pubmed
Then , we conducted multivariate Cox analysis to assess the independent effect of the PLR on the survival of
GBC patients . -
pubmed
CONCLUSION : The PLR could be used as a simple , inexpensive , and valuable tool for predicting the prognosis of
GBC patients . -
pubmed
David 's procedure is also feasible in
patients with
bicuspid aortic valve (
BA ) , though few long - term data are available . -
pubmed
METHODS : An analysis was conducted of the long - term echocardiographic data from
patients with
BAV who had undergone David 's procedure at early and long - term follow up ( FU ) examinations . -
pubmed
RESULTS : Between 1994 and 2010 , a total of 30
patients with
BAV underwent David 's procedure at the authors'institution . -
pubmed
Four
patients ( 13 % ) had to be reoperated after 10.00 + - 4.74 years ( range : 5.49 - 17.06 years ) due to
aortic stenosis ( n = 1 ) and
aortic insufficiency ( n = 3 ) ; the latter three
patients had a significant
prolapse of both the fused and the non - coronary cusp of reconstruction . -
pubmed
Patients with prolapsing non - coronary leaflet at reconstruction seemed vulnerable to recurrent
AR . -
pubmed
METHODS AND RESULTS : Four groups of
patients undergoing TAVI in the Placement of Aortic Transcatheter Valves ( PARTNER ) trial and registries were compared : prior PPM ( n=586 ) , new PPM ( n=173 ) , no
PPM ( n=1612 ) , and
left bundle branch block ( LBBB)/no PPM ( n=160 ) . -
pubmed
CONCLUSIONS : In the PARTNER trial , prior PPM , along with new PPM and chronic
LBBB patients , had worsened clinical and echocardiographic outcomes relative to no PPM patients , and the presence of a
PPM was independently associated with 1 - year mortality . -
pubmed
chagasi was expressed in three different
strains of
Escherichia coli . -
pubmed
chagasi may be a useful tool in the diagnosis of
CVL , and further tests regarding the
infection stage and the specie of parasite at which the
dogs are sampled should provide a better understanding of our results . -
pubmed
The treatment goal for
CBS - deficient patients is to normalize the metabolic values of these three metabolites using a combination of vitamin therapy and dietary manipulation . -
pubmed
To better understand the effectiveness of nutritional treatment strategies , we have performed a series of long - term dietary manipulation studies using our previously developed Tg - I278 T Cbs(-/- )
mouse model of
CBS deficiency and sibling Tg - I278 T Cbs(+/- ) controls . -
pubmed
BACKGROUND :
Femoroacetabular impingement (
FAI ) has been reported as a cause of
hip pain in young
patients and is suggested as the trigger for
hip osteoarthritis (
OA ) . -
pubmed
The goal of this study was to quantify the metabolic profiles of articular tissues ( cartilage , synovium , and labrum ) harvested from
patients with
FAI and with
end - stage OA . -
pubmed
The differences in gene expression in articular tissues from the
patients with
FAI were also evaluated on the basis of clinical parameters ( age range and alpha angle ) . -
pubmed
CONCLUSIONS : Our results indicate that the metabolic conditions of articular cartilage in
FAI and
OA are different and that the expression of genes associated with
inflammation is greater in the articular cartilage of
patients with
FAI compared with the synovium and the labrum . -
pubmed
CLINICAL RELEVANCE : The articular cartilage from the
impingement lesion in
patients with
FAI showed biologically higher
inflammation and degeneration , supporting the concept that FAI may be a trigger for
joint degeneration . -
pubmed
METHODS : A total of 172 multiply injured
patients ( mean Injury Severity Score [ ISS ] 26.7 ) recruited from eight
trauma centres participating in the German Trauma Registry were compared with 166 marginally injured
patients ( mean ISS 3.9 ) . -
pubmed
Deep brain stimulation at low frequency improves
dysphagia and freezing of gait in
Parkinson patients . -
pubmed
Bimagrumab seems to increase muscular volume and force in
patients with
inclusion body myositis . -
pubmed
Place of
Colistin -
Rifampicin Association in the Treatment of Multidrug - Resistant
Acinetobacter Baumannii Meningitis : A Case Study . -
pubmed
Treatment of
Acinetobacter baumannii meningitis is an important challenge due to the accumulation of resistance of this bacteria and low meningeal diffusion of several antimicrobial requiring use of an antimicrobial effective combination to eradicate these species . -
pubmed
We report a case of
Acinetobacter baumannii multidrug - resistant
nosocomial meningitis which was successfully treated with intravenous and intrathecal
colistin associated with
rifampicin . -
pubmed
Proton Therapy in
Children : A Systematic Review of Clinical Effectiveness in 15 Pediatric
Cancers . -
pubmed
For
chondrosarcoma ,
chordoma ,
craniopharyngioma ,
ependymoma ,
esthesioneuroblastoma ,
Ewing sarcoma , central nervous system
germinoma ,
glioma ,
medulloblastoma ,
osteosarcoma , and
rhabdomyosarcoma , there was insufficient evidence to either support or refute PT in
children . -
pubmed
For patients with
RRMS , what are the pharmacological strategies for
patients not adequately controlled on initial pharmacotherapy ? -
pubmed
Should combination strategies be considered for treatment of
patients with
RRMS ? -
pubmed
We aimed to assess the outcomes after a single catheter ablation procedure , comparing PVI using CRYO vs. RF ablation for PVI plus additional ablation in a cohort of
patients with persistent
AF . -
pubmed
METHODS : In this prospective multicenter propensity score - matched comparison , 59 consecutive
patients undergoing CRYO ablation of persistent
AF were matched to 59
patients treated with RF from November 2010 to June 2012 . -
pubmed
RESULTS : During a mean follow - up of 15.6 + - 11.5 months , 43.2 % of
patients presented
atrial arrhythmia relapse after a blanking period of 3 months , which was comparable between the two groups ( 40.7 % in CRYO vs. 45.8 % in RF , Log rank P = 0.14 ; HR = 0.67 , 95 % CI 0.38 - 1.16 , P = 0.15 ) , despite the fact that 52.5 % of RF
patients add additional complex fractionated atrial electrogram ablation , as well as left atrial linear ablation in over two - thirds ( roof line in 67.8 % and
mitral isthmus in 32.2 % ) . -
pubmed
CONCLUSION : In our multicenter experience , freedom from
atrial arrhythmias was comparable among matched
patients treated with CRYO and RF , despite non - significant trends in favor of RF in terms of complications , at the cost of longer procedure times . -
pubmed
Here we compare genital shedding patterns of
herpes simplex virus-2 (
HSV-2 ) in 98
HIV infected and 98
HIV uninfected men matched on length of
infection , HSV-1 serostatus and nationality . -
pubmed
Iron Deficiency Induces a Partial Inhibition of the Photosynthetic Electron Transport and a High Sensitivity to Light in the Diatom
Phaeodactylum tricornutum . -
pubmed
In this study , a combination of thermoluminescence ( TL ) ,
chlorophyll fluorescence , and P700 absorbance measurements have been used to elucidate the effects of
iron deficiency in the photosynthetic electron transport of the marine diatom
P. - pubmed
Iron deficiency also induced a marked increase in
light sensitivity in
P. - pubmed
A reduction in left ventricular ( LV ) global longitudinal
strain in all
patients , or reduction in LV global circumferential
strain or global radial
strain in
patients at intermediate to high risk for
cardiotoxicity , despite normal LV ejection fraction warrants a clinical assessment on the benefits of continuing cardiotoxic chemotherapeutic agents . -
pubmed
Listeria monocytogenes sequence type 204 ( ST204 )
strains have been isolated from a range of food , environmental , and clinical sources in Australia . -
pubmed
All
patients alive 90 days after pancreatoduodenectomy for M0 -
pancreatic cancer between 2008 and 2013 in the Netherlands were included in this study . -
pubmed
Of the 1195
patients undergoing a pancreatoduodenectomy for
pancreatic cancer , 642 ( 54 % )
patients received adjuvant chemotherapy . -
pubmed
Patients with a higher
tumor stage , younger age , and diagnosed more recently were more likely to receive adjuvant treatment . -
pubmed
The finding that elderly
patients and
patients with a low
tumor stage are less likely to undergo treatment needs further attention , especially since adjuvant treatment is known to prolong survival in most of these
patients . -
pubmed
OBJECTIVE : To evaluate potential development of tolerance to adjunctive
clobazam in
patients with
Lennox - Gastaut syndrome . -
pubmed
Individual
patient listings were reviewed for dosage increases & gt;=40 % and increasing
seizure rates . -
pubmed
For
patients free of drop
seizures , there was no notable change in dosage over 24 months . -
pubmed
Few
patients had a dosage increase & gt;=40 % associated with an increase in
seizure rates . -
pubmed
A total of 16
patients ( 20.8 % ) had severe
postoperative thrombocytopenia ( & lt;50x103 / mm3 ) . -
pubmed
The incidence of severe
thrombocytopenia was significantly higher ( p = 0.046 ) in Perceval S
patients ( n = 9 ; 33.3 % ) than in Mitroflow patients ( n = 7 ; 14 % ) . -
pubmed
The platelet count recovered in all
patients with severe
thrombocytopenia . -
pubmed
To further understand the role of lipogenesis and lipotoxicity in the development of
obesity and
diabetes , lipidomes of various organs from ob / ob
mice and their wild type controls were analyzed by shotgun lipidomics at 10 , 12 , and 16 weeks of age . -
pubmed
Moreover , levels of lipotoxic
lipid classes were significantly higher in ob / ob
mice than their age - matched controls , supporting the notion that elevated lipotoxic components are tightly associated with
insulin resistance in ob / ob
mice . -
pubmed
Taken together , the current study revealed that lipogenesis and lipotoxicity in ob / ob
mice likely contribute to
insulin resistance and provides great insights into the underlying mechanisms of
diabetes and
obesity . -
pubmed
METHODS : We prospectively studied 708 type-2
diabetes patients [ 433
men ( [ 61.2 % ) ] , candidate for isolated coronary artery bypass grafting . -
pubmed
All
patients were telemonitored for 72 hours after operation for the occurrence of
atrial fibrillation . -
pubmed
RESULTS : A total of 109 ( 15.3 % )
patients developed
POAF . -
pubmed
Patients in the
atrial fibrillation group tended to be older , with prolonged longer
diabetes , and have
renal failure ,
chronic obstructive pulmonary disease , and
hypertension . -
pubmed
Medical Management of Extensive Arterial
Thromboembolism in a
Patient with
Essential Thrombocythemia and
Warfarin Failure . -
pubmed
Patients with
ET and
PV are at an increased risk for
thromboembolic and hemorrhagic events . -
pubmed
We assessed the preliminary efficacy , tolerability , and safety of
azithromycin compared with placebo in the treatment of
OCD and associated symptoms in
children with pediatric acute - onset
neuropsychiatric syndrome (
PANS ) . -
pubmed
The primary outcome ,
obsessive - compulsive symptom severity , was assessed using the OCD Clinical Global Impressions Severity ( CGI - S OCD ) and
Children 's Yale - Brown Obsessive Compulsive Scale ( CY - BOCS ) . -
pubmed
RESULTS :
Participants in the
azithromycin group ( n = 17 ) showed significantly greater reductions in
OCD severity on the CGI - S
OCD than the placebo group ( n = 14 ) posttreatment ( p = 0.003 ) , although there were no significant differences on the CY - BOCS . -
pubmed
OBJECTIVES : Statins may improve outcomes in
patients with
chronic liver disease (
CLD ) . -
pubmed
METHODS AND MATERIALS : A retrospective analysis of
patients receiving palliative RT for axial skeletal bone
metastases from 2012 to 2014 was conducted . -
pubmed
Patient and treatment characteristics were obtained including dosimetric variables ,
acute toxicity , and subjective
pain during treatment and in the acute posttreatment period ( & lt;=60 days after completion ) . -
pubmed
The patient was an emergency transported , 57 - year - old
man complaining of left thoraco - lateroabdominal
pain , with a history of blunt
chest trauma 3 months prior . -
pubmed
Laparoscopic - assisted percutaneous nephrolithotomy as an alternative in the treatment of complex
renal calculi in
patients with retrorenal colon . -
pubmed
There were 969 case
patients who experienced a primary cardiovascular outcome , and there were 3170 control
patients who were event free at the time of a case event and had the same type of index
ACS ( unstable
angina or
myocardial infarction ) as that of the respective case
patients . -
pubmed
OBJECTIVE : To evaluate outcomes for RBU in a multi - institutional cohort of
patients treated for revision ureteropelvic junction obstruction and long or multifocal
ureteral stricture at three tertiary referral centers . -
pubmed
This study aims to evaluate the impact of covert
hepatic encephalopathy on the emotional state and which factors are associated with changes in the emotional state in
patients with
cirrhosis . -
pubmed
METHODS : This single - center study included all
patients with
cirrhosis who underwent the
portosystemic encephalopathy syndrome ( PSE ) test , critical flicker frequency , and emotional state assessment with the Eigenschaftsworterliste 60 - S in 2011 . -
pubmed
RESULTS : One hundred seventeen
patients with
cirrhosis were included ( median age : 59 [ interquartile range : 48 - 67 ] , 32 % female , 74 %
alcohol - associated ) . -
pubmed
Seventy
patients had covert
hepatic encephalopathy ( 60 % ) with a higher MELD ( 16 [ interquartile range : 13 - 21 ] , p = 0.001 ) and a higher Child - Pugh score ( p = 0.003 ) compared to patients without
encephalopathy . -
pubmed
Patients with covert
encephalopathy felt reduced mental activity ( p = 0.004 ) , lower general well - being ( p = 0.001 ) , and reduced extraversion ( p = 0.021 ) . -
pubmed
The scores in the negative domains such as general
lethargy ( p = 0.031 ) and
anxiousness /
depressiveness ( p = 0.033 ) were higher in
patients with covert
hepatic encephalopathy . -
pubmed
Patients with 2 pathological tests ( critical flicker frequency and PSE ) showed the most distinct alterations in the emotional state in the group of
patients with covert
hepatic encephalopathy . -
pubmed
CONCLUSIONS :
Patients with covert
hepatic encephalopathy have an alteration of the emotional state , which is more marked in patients with 2 pathological tests . -
pubmed
Across a range of countries , the model results indicate that a more efficient allocation of
HIV resources could reduce cumulative new
HIV infections by an average of 18 % over the years to 2020 and 25 % over the years to 2030 , along with an approximately 25 % reduction in
deaths for both timelines . -
pubmed
METHODS : Seventy - nine
patients diagnosed with
OCD who received a standardized combination of treatments for 10 continuous years were divided into three groups according to their improvement rates on the Yale - Brown Obsessive - Compulsive Scale after 10 years of treatment . -
pubmed
Prevalence and distribution of
HPV genotypes and
cervical - associated lesions in sexually active young French women following
HPV vaccine . -
pubmed
OBJECTIVE : To estimate the overall prevalence and distribution of
HPV in vaccinated , sexually active young French women who were screened for
cervical cancer by cytology and
HPV testing . -
pubmed
METHODS : High - risk
HPV ( HR -
HPV ) prevalence , genotype - specific prevalence and extent of
multiple infections were assessed in 125 cervical samples from females with available vaccine data using hc2 assay and INNO - LiPA assay . -
pubmed
CONCLUSION : Among
HPV - vaccinated young women ,
HR - HPV are detected at a high rate , and an association with the grade of cytological abnormalities was observed . -
pubmed
Congenital Microphthalmic Syndrome in a
Swine . -
pubmed
A 17 - week - old crossbred finishing
pig was presented for
lameness of approximately one week . -
pubmed
To the authors ' knowledge , this is the first case report describing in detail histopathological changes in the
porcine congenital microphthalmic syndrome . -
pubmed
The role of extended infusion
beta - lactams in the treatment of
bloodstream infections in
patients with
liver cirrhosis . -
pubmed
INTRODUCTION :
Bloodstream infections (
BSIs ) in
patients with
liver cirrhosis are associated with significant morbidity and mortality . -
pubmed
Areas covered : This review covers several aspects of how the pharmacokinetic / pharmacodynamic behavior of antimicrobials may change in
patients with
liver cirrhosis . -
pubmed
Common features of
cirrhosis , including
hypoproteinemia , third space expansion and
impairment of renal function may alter drug distribution in
patients receiving hydrophilic drugs like
beta - lactams , which are often frontline agents . -
pubmed
Expert commentary : Observational studies have suggested that
cirrhotic patients have improved outcomes when
beta - lactam therapy is administered by extended or continuum infusion . -
pubmed
Further studies are being completed to determine the optimal timing , depth and duration of
hypothermia to optimize
patient outcomes . -
pubmed
METHODS : This was a cross - sectional study of 403
participants with
asthma , aged 17 - 75 years , from three Swedish centres . -
pubmed
CASE DESCRIPTION : The
patient presented with
heart failure immediately after birth . -
pubmed
Patient 's characteristics at baseline , including New York Heart Association class , ejection fraction , QRS width and morphology , ischaemic aetiology of
cardiomyopathy (
ICM ) , number of scarred segments , age at implantation ,
atrial fibrillation , and mechanical dyssynchrony ( Dyss ) were analysed . -
pubmed
Women ( 24 % of the population ) had less ICM ( 23 % vs. 49 % , P & lt ; 0.0001 ) , less scarred segments ( 0.4 + - 1.3 vs. 1.0 + - 2.1 , P & lt ; 0.0001 ) , more
left bundle branch block ( LBBB ; 87 % vs. 80 % , P = 0.01 ) , and more Dyss at baseline ( 78 % vs. 57 % , P & lt ; 0.0001 ) . -
pubmed
Its antibacterial activity over six oral
bacteria was analyzed using the microdilution method , and its
cytotoxicity in osteoblasts was assessed with the
MTT assay . -
pubmed
Of the five Plasmodium species that are pathogenic to
humans ,
infection with
Plasmodium falciparum leads to fulminant progression of the disease with massive impact on pregnancy . -
pubmed
Clinical efficacy of acute
respiratory viral infections prevention in
patients with chronic
heart failure . -
pubmed
MATERIALS AND METHODS : Conducted a comprehensive survey , dynamic monitoring and treatment of 60
patients aged from 49 to 70 years ( mean age 60.25 + -4.57 years , 17
men and 43
women ) with
CHF with preserved ejection fraction of left ventricle ( LVEF ) ( & gt;=50 % ) , II - III functional class ( FC ) according to the classification of new York Heart Association ( NYHA ) , which developed as a result of
coronary heart disease (
CHD ) ,
hypertensive disease (
HD ) . -
pubmed
Of these , 30
patients ( group 1 ) on the background of standard therapy for
CHF received for the prevention of ARVI
tiloron (
Amixin ) at a dose of 125 mg once a week for 6 weeks , two courses for 1 year . -
pubmed
Group 2
patients received only standard therapy for
CHF . -
pubmed
The positive dynamics of biomarkers of
systemic inflammation and neurohormonal activation explains the improvement of the clinical course in
patients with
CHF ( increase of tolerance to physical loads , reducing the number of visits to General practitioner and hospital admissions in the hospital during 12 months of observation ) . -
pubmed
CONCLUSION : A promising approach to the prevention of
SARS in
patients with
CHF is course therapy with
Amixin ( 2 times a year before the seasonal rising in the incidence of
respiratory viral infections and
influenza ) , which allows to achieve both decreasing in the frequency of
SARS per year , and improvement the clinical course of
CHF . -
pubmed
A total of 60
participants with
SAP ( n=20 ) ,
AMI ( n=20 ) and non -
CHD controls ( n=20 ) were enrolled . -
pubmed
Moreover , there was a more marked increase in the expression of these indicators in
AMI patients when compared to
SAP patients . -
pubmed
Association between physician - staffed ambulances and
patient prognoses after out - of - hospital
cardiac arrests with respect to shockable and non - shockable rhythms : a retrospective observational study in a southern area of Shiga Prefecture Japan . -
pubmed
Our observations could provide more appropriate prehospital treatment options for
OHCA patients . -
pubmed
parahaemolyticus to twenty - six bacterial and
yeast strains and use the beneficial ones to enrich live food ( Branchiopod ,
Artemia franciscana , rotifer ,
Brachionus plicatilis and copepod ,
Tigriopus japonicus ) . -
pubmed
From the total bacteria and
yeast strains that were used ,
Candida parapsilosis ,
Pseudoalteromonas flavipulchra ,
Lactobacillus sakei ,
Bacillus natto , and
B. - pubmed
Obstructive voiding symptoms in female
patients with
overactive bladder syndrome . -
pubmed
The proportions of
patients who suffered
relapse after 6 months , 1 year , and 2 years were 28 % , 31 % , and 40 % for the postpartum group and 39 % , 50 % , and 55 % for the nonpostpartum group . -
pubmed
Contrast sensitivity and visual acuity in
subjects wearing multifocal contact lenses with high additions designed for
myopia progression control . -
pubmed
Correction to : Oral inoculation of ultraviolet - irradiated Eimeria species oocysts protects
chickens against
coccidiosis . -
pubmed
The Short - Term Cost - Effectiveness of Once - Weekly Semaglutide Versus Once - Daily
Sitagliptin and Once - Weekly Dulaglutide for the Treatment of
Patients with
Type 2 Diabetes : A Cost of Control Analysis in Spain . -
pubmed
These trials also assessed the proportions of
patients achieving treatment targets capturing glycemic control and avoidance of
hypoglycemia and
weight gain . -
pubmed
This study assessed the cost of bringing
patients with
type 2 diabetes to three clinically relevant endpoints with
semaglutide versus
sitagliptin and
dulaglutide in Spain . -
pubmed
METHODS : The proportions of
patients achieving endpoints of HbA1c < 7.0 % , HbA1c < 7.0 % without
hypoglycemia and without
weight gain , and a > = 1.0 % HbA1c reduction with > = 5.0 %
weight loss were taken from SUSTAIN 2 and 7 . -
pubmed
The largest increase was found in miR-125a in the
FXS sample , and the miR-125a levels were increased in two independent sets of urine samples from a total of 19
FXS children . -
pubmed
The Panther Fusion respiratory panels consist of 3 separate multiplex assays that test for 1 )
influenza A ,
influenza B , and
RSV ; 2 )
parainfluenza virus types 1 - 4 ; or 3 ) adenovirus ,
human metapneumovirus , and rhinovirus . -
pubmed
A paradigm shift is underway from the current focus of drug development targeting the pathogen , to advancing cellular Host - Directed Therapies ( HDTs ) for tackling the aberrant host immune and inflammatory responses which underlie the pathogenesis of
SARS - CoV-2 and high
COVID-19 mortality rates . -
pubmed
Background : We aim to evaluate the speed and rates of reperfusion in tandem large vessel occlusion
acute stroke patients undergoing upfront cervical lesion treatment ( Neck - First : angioplasty and/or stent before thrombectomy ) as compared to direct intracranial occlusion therapy ( Head - First ) in a large international multicenter cohort . -
pubmed
Results : In total , 289
patients with tandem
atherosclerotic etiology were included in the analysis ( 182 Neck - First and 107 Head - First
patients ) . -
pubmed
Conclusions : The upfront approach of the intracranial lesion in
patients with tandem large vessel occlusion
strokes leads to similar reperfusion rates but faster reperfusion as compared to initial cervical revascularization followed by mechanical thrombectomy . -
pubmed
METHODS : Paired
cancerous and pre -
cancerous tissues surgically resected from
EC patients were collected in this study . -
pubmed
: The leaves of
Bersama abyssinica are used for the treatment of
diabetes mellitus in folk medicine system of Ethiopia . -
pubmed
The present study was done based on the traditional claim of
B abyssinica for the treatment of
diabetes mellitus . -
pubmed
Blood
glucose lowering activity of the extracts was studied in 4
animal models ; normoglycemic , oral
glucose loaded , and
streptozotocin - induced
diabetic mice models . -
pubmed
The crude extract at doses of 200 , and 400 mg / kg showed significant ( P < .05 )
hypoglycemic activity in normoglycemic
mice . -
pubmed
Background :
Fatigue and
insomnia are common symptoms experienced by
breast cancer patients undergoing adjuvant radiation therapy ( RT ) , yet the underlying mechanisms of these symptoms are unclear . -
pubmed
Methods :
Breast cancer patients ( n = 147 ) completed questionnaires to longitudinally assess symptoms before , during , and after adjuvant RT . -
pubmed
Carbon tetrachloride (
CCl4 ) was applied to create a
mouse liver fibrosis model . -
pubmed
Trabectedin Plus Radiotherapy for Advanced
Soft - Tissue Sarcoma : Experience in Forty
Patients Treated at a
Sarcoma Reference Center . -
pubmed
Symptomatic control and tumoral shrinkage is an unmet need in advanced
soft - tissue sarcoma (
STS )
patients beyond first - line . -
pubmed
We retrospectively reviewed advanced
sarcoma patients treated with
trabectedin concomitantly with radiotherapy with palliative intent . -
pubmed
The combination of
trabectedin plus radiotherapy is an active therapeutic option in
patients with advanced
STS , especially when
tumor shrinkage for symptomatic relief is needed . -
pubmed
Background : The Acupuncture Trialists ' Collaboration has updated its individual
patient data meta - analysis of acupuncture for
chronic pain originally published in 2012 . -
pubmed
Two out of four
HCV+ donors were
viremic at the time of explantation . -
pubmed
Purpose : To evaluate the predominant pathogens and clinical course in pediatric
patients with
orbital cellulitis (
OC ) complicated by
subperiosteal abscess (
SPA ) . -
pubmed
Methods : This is a single - center retrospective chart review evaluating pediatric
patients with
OC complicated by
SPA treated at a tertiary care center in the Pacific Northwest . -
pubmed
Results : Twenty - seven
children were identified with
OC complicated by
SPA and
bacterial cultures drawn . -
pubmed
Pediatric
patients with
SAG infections required more surgery than children without this isolate , 100 % and 65 % , respectively ( p = .030 ) . -
pubmed
BACKGROUND :
Patients with
human papillomavirus - related
oropharyngeal cancers have excellent outcomes but experience clinically significant toxicities when treated with standard chemoradiotherapy ( 70 Gy ) . -
pubmed
METHODS : In 19
patients , pre- and intratreatment dynamic
fluorine-18 - labeled fluoromisonidazole positron emission tomography ( PET ) was used to assess
tumor hypoxia . -
pubmed
Patients without
hypoxia at baseline or intratreatment received 30 Gy ;
patients with persistent
hypoxia received 70 Gy . -
pubmed
RESULTS : Fifteen of 19
patients had no
hypoxia on baseline PET or resolution on intratreatment PET and were deescalated to 30 Gy . -
pubmed
Infection with
mycobacterium kansasli and
cryptococcus neoformans . -
pubmed
EEG , regional cerebral blood flow ( rCBF ) and neuropathological autopsy data were studied in 17
patients with
presenile dementia . -
pubmed
In contrast , the Pick ( DFT )
patients had normal EEGs which remained so even late in the course when the signs of
dementia were marked . -
pubmed
( some comments on their relation with
human eosinophilic granuloma ) ( author 's transl ) ] . -
pubmed
Prostaglandins in cerebrospinal fluid of
patients during various
infectious diseases . -
pubmed
In accord with the results of animal experiments
prostaglandins of the E series seem to act as mediators of
fever during
infectious diseases also in
man . -
pubmed
This study demonstrated that treatment aiming at reducing the subgingival bacterial mass and suppressing the anaerobic segment had a beneficial effect in
patients suffering from
peri - implantitis . -
pubmed
Because further immunosuppression would predispose the transplant
patient to other
opportunistic infections , we advocate a trial of plasmapheresis in the treatment of
Guillain - Barre syndrome in this population . -
pubmed
Postnatal behavioral development in
methylazoxymethanol - induced
microcephalic rats -- a behavioral teratology study . -
pubmed
Behavioral testings in
methylazoxymethanol (
MAM)-induced
microcephalic rats were conducted . -
pubmed
Maudsley reactive ( MR ) and nonreactive ( MNRA ) and Sprague - Dawley ( SD ) male
rats were tested for their immobility response in the forced swim test when the water was fresh or soiled by a
rat of the same or other
strain . -
pubmed
For all
strains ,
rats tested in soiled water were less immobile than
rats in fresh water . -
pubmed
The interpretation of these findings regarding the use of the Maudsley
rat strains as an
animal model for studying
anxiety and/or
depression is discussed . -
pubmed
Effects of
guanethidine on sensitization to natural stimuli and self - mutilating behaviour in
rats with a
peripheral neuropathy . -
pubmed
In the present study we have used a recent
rat model for
neuropathic pain to investigate the effect of the sympatholytic drug
guanethidine on changes in behavioural responses evoked by mechanical , heat and cold stimuli and on self - mutilating behaviour . -
pubmed
After a unilateral
peripheral mononeuropathy induced by ligatures around the right common sciatic nerve , the left side receiving just a sham
wound , lesioned and non - operated control
animals were treated with saline or
guanethidine ( 30 mg / kg ) for 4 consecutive days commencing 5 days before or 10 days after surgery . -
pubmed
PURPOSE : To investigate the effects of chronic subcutaneous administration of
reserpine (
Res ) or
propranolol (
Prop ) on the postinfarction
myocardial hypertrophy and the effects of
Prop treatment on myocardial contractility in
rats . -
pubmed
METHODS : Male
albino rats ( 3 - month - old ) were submitted to left coronary artery ligation to produce
myocardial infarction . -
pubmed
Comparison of management outcome of primary and secondary referred
patients with
traumatic extradural haematoma in a neurosurgical unit . -
pubmed
A total of 104
patients with a traumatic extradural
haematoma in a 5 - year period were studied . -
pubmed
This better result was associated with a shorter delay between the time of conscious level deterioration and decompressive operation : 0.7 + /- 1.0 h vs 3.2 + /- 0.5 h. Direct admission of all
head injured patients to a neurosurgical unit resulted in significant reduction in mortality and morbidity in
patients with an extradural
haematoma . -
pubmed
in 6
patients , in 5 it was terminated early because of typical signs of clinical
hypoglycaemia . -
pubmed
The course of the blood
sugar curves revealed differences between
patients from abrupt drops of
hyperglycaemic values to
hypoglycaemia to balanced low blood
sugar levels . -
pubmed
The danger of early
hypoglycaemia within 60 minutes was recorded only in
patients with a known history of severe
hypoglycaemic states . -
pubmed
The authors described 2
patients with
spinal tuberculosis . -
pubmed
Staphylococcus aureus nasal carriage and
infection in patients on continuous ambulatory peritoneal dialysis . -
pubmed
We studied 140 consecutive
patients beginning continuous ambulatory peritoneal dialysis ( CAPD ) at one of seven hospitals to assess the relation of the nasal carriage of
Staphylococcus aureus to subsequent catheter - exit - site
infection or
peritonitis . -
pubmed
The rates of
peritonitis of all bacterial types did not differ significantly between the groups , but all 11 episodes of
peritonitis caused by
S. - pubmed
The
patient presented without
hypercalcemia , or
urinary infection , or
renal tubular acidosis , or
ureteral obstruction , or ingestion of antacids , or
metabolic disease , or previous graft
lithiasis . -
pubmed
A multifocal outbreak of
hepatitis A traced to commercially distributed
lettuce . -
pubmed
Case - control studies of patrons of two of these restaurants found that eating
green salad was strongly associated with acquiring
hepatitis A : OR = 11.6 and OR = 4.4 . -
pubmed
A 37 - year - old
woman with diagnosis of
thalassemia intermedia was admitted because of mild
dyspnea and
edema of her lower extremities . -
pubmed
Prevention of
autoimmune damage to islet grafts in BB
rats by antibody therapy . -
pubmed
One hundred and twenty - four
patients had a postanal repair for the treatment of
faecal incontinence between January 1976 and July 1987 . -
pubmed
Incontinence was improved in 81 per cent of
patients . -
pubmed
Thirty
patients with long - standing ( mean 30 days ) type I
atrial flutter (
AF ) were treated with overdrive atrial pacing . -
pubmed
Pacing was performed from a mean number of 2.1 sites per
patient in Group A , 1.2 in B and 2.0 in C.
Atrial fibrillation occurred in 7 , 3 and 4
patients , respectively . -
pubmed
Acceleration of
atrial flutter to a faster form of
AF occurred in 3 , 3 and 4
patients , respectively . -
pubmed
The administration of
DISO is beneficial when overdrive atrial pacing is performed for the treatment of long standing
AF in
patients with
organic heart disease . -
pubmed
Perinatal outcomes of these pregnancies were compared with perinatal outcomes of a matched group of obstetric
patients with no history or evidence of
substance abuse ( group 3 [ N = 40 ] ) . -
pubmed
Group 2
women had an increased rate of
preterm delivery and low - birth - weight infants as well as an increased rate of
intrauterine growth retardation . -
pubmed
The protection afforded by the inhaled muscarinic cholinergic antagonist ,
ipratropium bromide ( IB ) 1 mg , from
bronchoconstriction induced by inhaled
adenosine was compared with that of
methacholine in 8
allergic asthmatic subjects . -
pubmed
The authors relate the case of two
patients of 61 and 64 years old , each one having a
high latero - cervical tumor ,
arching the soft palate , developed from the right vagus nerve and which was a chromaffin
paraganglioma . -
pubmed
Anismus , or
constipation due to functional obstruction at the pelvic outlet by paradoxical contraction of the striated sphincter muscles during defaecation straining , is described in ten
constipated patients and four
patients with
Parkinson ' s disease and
constipation . -
pubmed
A case of multiple
intracranial arterial aneurysms occurring in a 43 year - old
patient with an 8 - year history of
Behcet ' s disease is reported . -
pubmed
Decrease in number of
hippocampal gamma - aminobutyric acid ( GABA ) immunoreactive cells in the
rat kindling model of
epilepsy . -
pubmed
[
Human parasitosis in Mexico ] . -
pubmed
Myocardial involvement in progressive
muscular dystrophy of the
Duchenne type was evaluated in 19
patients using
thallium-201 myocardial perfusion imaging . -
pubmed
Extensive perfusion defects were shown in 2
patients who died of
congestive heart failure 1 to 2 years after the scintigraphic study . -
pubmed
Increased
renal carcinogenesis by
dimethyl nitrosamine in
protein deficient rats . -
pubmed
Diacytosis of 125I - asialoorosomucoid by
rat hepatocytes . -
pubmed
Eighty - one
patients with
rosacea were treated with either I%
metronidazole cream or the cream base as a placebo for two months . -
pubmed
The first case of
haemolytic anaemia with
thrombocytopenia and
acute renal failure induced by ingestion of
aspirin in a 22 - year old
woman is reported . -
pubmed
In addition , the allergic nature of the
patient 's
hypersensitivity to
aspirin was confirmed by positive lymphocyte transformation and basophil degranulation tests in the presence of the drug . -
pubmed
Body weights were not changed by either treatment , although they were greater for the CD broilers than for the SAD
broilers . -
pubmed
Aberrations in T - cell subpopulations in
patients with
psoriasis and
psoriatic arthritis . -
pubmed
Peripheral blood T - cell subpopulations and B - cell numbers from 25
patients with
uncomplicated psoriasis and 22
patients with
psoriatic arthritis were compared with those of 24 age- and sex - matched healthy volunteers and 11
patients with radiologically defined
erosive osteoarthritis . -
pubmed
The numbers of early and late rosettes were found to be reduced in
patients with
psoriasis , with and without
arthritis , while the total T - cell population ( measured by
aminoethylthiouronium bromide - rosettes ) was found to be normal . -
pubmed
There was no difference in the number of B cells between
psoriatic patients and controls . -
pubmed
The pokeweed mitogen response , however , was reduced in
patients with
cutaneous psoriasis and increased in
patients with
psoriatic arthritis . -
pubmed
These studies further support the concept of an immunologic imbalance in lymphocyte populations from
patients with
psoriasis and
psoriatic arthritis . -
pubmed
Haematological and rheological ( plasma and serum viscosity , whole blood viscosity , and erythrocyte filterability ) factors were studied in 31 age - sex matched pairs of
patients with
sickle cell haemoglobin C disease with and without
proliferative sickle retinopathy (
PSR ) . -
pubmed
Growth , food intake , motor activity and experimental
cardiac necrosis in early malnourished male
rats . -
pubmed
Male
rats with
protein energy malnutrition from birth to the 49th day of life ( PEM ) and then receiving normal diet ad libitum had lower
body weights and relatively higher food intakes ( g/100 g
body weight ) than controls ( C ) . -
pubmed
the
cardiac damage was smaller in previously malnourished
animals ( PEM ) . -
pubmed
The administration of
dibekacine to 10 newborn carriers of a
germ infection -- or
staphylococcus , was controlled for auditory tolerance . -
pubmed
Sequential femoropopliteal - tibial grafts have been advocated as a promising treatment for use in
patients with severe
ischemia of the distal lower extremity . -
pubmed
M - mode and two - dimensional parasternal long axis view echocardiography , and left anterior oblique cineangiography were employed to assess the left ventricular wall motion in 10 normal
subjects ( N ) and in 25
patients with
hypertrophic cardiomyopathy : 7
patients with symmetric
hypertrophy (
SH ) and 6
patients with
apical cardiomyopathy (
AHCM ) and no intraventricular gradient ; 12
patients with
hypertrophic obstructive cardiomyopathy and asymmetric
septal hypertrophy with resting intraventricular gradient ( 6 pts ) ( HOCM - R ) or gradient occurring only after
isoproterenol infusion ( 6 pts ) ( HOCM - I ) . -
pubmed
The histories of two
patients with
restrictive ophthalmopathy are reported in whom the initial diagnosis was delayed primarily due to the relatively acute onset . -
pubmed
The uptake of
mercury in the species investigated varied considerably , being highest in the two
strains of
mice , followed by
rat and
hamster , and lowest in the guinea - pig . -
pubmed
The two
strains of
mice were exposed to a wide range of
mercury concentrations in air ( 0.002 - 3.5 mg / m3 ) . -
pubmed
In acatalasemic
mice the
mercury content in liver was higher at all concentrations investigated , whereas in brain no difference between the two
strains was found . -
pubmed
Serum antibodies to
hepatitis C virus (
HCV ) were tested for inpatients undergoing allogeneic BMT to determine the risk of acquiring
HCV infection and the role of
HCV in posttransplant liver complications . -
pubmed
Before screening for non - A ,
non - B hepatitis , 14 % of the patients seroconverted to
HCV ( 0.44 % per unit transfused ) . -
pubmed
Positive anti -
HCV status before and after BMT was not predictive of
veno - occlusive disease ,
liver graft - versus - host disease (
GVHD ) , or
death due to
liver dysfunction . -
pubmed
Group 1 comprised 27
patients ( seven with
gastric ulcers , 14 with
duodenal ulcers and six with
gastritis ) treated with a combination of
clarithromycin ( 200 mg , three times a day ) +
sofalcone ( 100 mg , three times a day ) for 3 weeks . -
pubmed
Group 2 comprised 15
patients with
chronic active gastritis treated with the same doses of
clarithromycin +
sofalcone but for only 2 weeks ( group 2 ) . -
pubmed
In these
patients , significant improvements were seen in the
gastritis score ( P & lt ; 0.025 ) , the index of
periodic acid - Schiff - positive substances in the antral mucosa ( P & lt ; 0.025 ) and the
ammonia concentration in gastric secretions ( P & lt ; 0.02 ) after treatment . -
pubmed
[ Recovery of
Staphylococcus aureus after
acid injury in milk products ] . -
pubmed
To determine the extent to which resorption contributes to the relative loss of bone during skeletal unloading of the growing
rat and to explore potential means of preventing such
bone loss , 0.1 mg P / kg
alendronate was administered to
rats before unloading of the hindquarters . -
pubmed
Detection of
Muerto Canyon virus RNA in peripheral blood mononuclear cells from patients with
hantavirus pulmonary syndrome . -
pubmed
Extrapulmonary thoracic disease caused by
Blastomyces dermatitidis . -
pubmed
A gene library constructed from large ( approximately 20 kb ) fragments of total DNA from the
geldananmycin - producing
strain Streptomyces hygroscopicus 3602 cloned in the plasmid vector pIJ61 were used to transform
S. - pubmed
Three transformants of about 800 tested were found to have acquired the ability to produce an antibiotic lethal to a
geldanamycin - sensitive
strain of
Bacillus subtilis . -
pubmed
Prevalence of
Helicobacter pylori infection and its effect on symptoms and non - steroidal anti - inflammatory drug induced
gastrointestinal damage in
patients with
rheumatoid arthritis . -
pubmed
Non - steroidal anti - inflammatory drugs ( NSAIDs ) and Helicobacter (
H pylori ) are both associated with an increased risk of
peptic ulceration and
gastropathy . -
pubmed
Fifty two
patients with
rheumatoid arthritis requiring longterm NSAID treatment were studied . -
pubmed
Patients with
H pylori infection ( n = 26 ) had a higher
dyspeptic symptom score ( p & lt ; 0.05 ) . -
pubmed
In mismatch repair - deficient
yeast strains , simple repeats are very unstable . -
pubmed
Liver tumors were the most frequently observed
neoplasms in these exposed
dogs and included 7 primary
hepatic hemangiosarcomas , 1
cholangiocarcinoma , 1
hepatocellular carcinoma , 1
fibrosarcoma , 4
biliary cystadenomas , and 1
fibroma . -
pubmed
The morphologic features of the
hemangiosarcomas and associated
hepatic lesions were similar to those described for
hemangiosarcomas induced in
people exposed to
Thorotrast . -
pubmed
Human colon
tumours usually form more
prostaglandins (
PGs ) than associated normal tissues , but the mechanism(s ) are not fully understood . -
pubmed
It is assumed that most cases of
nosocomial diarrhea are due to
Clostridium difficile because of the widespread use of broad - spectrum antibiotic agents . -
pubmed
In a total of 20
patients with persistent
hemodynamic depression despite mechanical ventilation plus
dopamine ( 10 - 12 micrograms / kg / min ) and
nitroglycerin ( 33 micrograms / min ) infusions additional therapy with
dobutamine ( maximal dose : 9 micrograms / kg / min ; n = 10 ) or
milrinone ( 0.5 microgram / kg / min ; n = 10 ) was started . -
pubmed
After 16 months facial and auriculotemporal nerve function was assessed and the
patient 's estimation of the
scar was registered . -
pubmed
Five percent of the
patients had transient
facial nerve weakness . -
pubmed
Auriculotemporal nerve weakness was reported by 34 % of the
patients . -
pubmed
None of the
patients found the
scars disfiguring . -
pubmed
In vivo electrically mediated protein and gene transfer in
murine melanoma . -
pubmed
We show that efficient permeabilization of
murine melanoma can be obtained in vivo by applying electric
pulses . -
pubmed
We studied aspects of cell - matrix interaction of myocytes in an esophagogastrectomy specimen from a 12 - year - old
patient with
DL . -
pubmed
Another group of
animals was irradiated under the same conditions but , for radioprotective purposes , were also in deep
hypothermia during radiation exposure . -
pubmed
In the upper jaws of the
animals exposed to irradiation , the
Se concentration was significantly lower than in those irradiated under conditions of
hypothermia ( p & lt ; 0.05 ) , although both groups showed no significant difference in
Se concentration when compared to nonirradiated controls . -
pubmed
In the lower jaws , the concentration of
Se was significantly reduced in the irradiated group when compared with controls and the
rats irradiated under conditions of
hypothermia ( p & lt ; 0.05 ) . -
pubmed
There was no significant difference in
Se concentration between
rats irradiated under conditions of
hypothermia and nonirradiated controls . -
pubmed
There was no significant change in
Se concentration in the jaws of the
rats protected by
hypothermia during radiation exposure compared with nonirradiated controls . -
pubmed
Pharmacokinetic and pharmacodynamic variations of
acenocoumarol orally administrated either once or twice daily in
patients with
deep venous thrombosis . -
pubmed
Antihepatotoxic potential of
Trianthema portulacastrum in
carbon tetrachloride - induced
chronic hepatocellular injury in
mice : reflection in haematological , histological and biochemical characteristics . -
pubmed
The effect of an ethanolic extract of the plant
Trianthema portulacastrum L. on the
CCl4 - induced
chronic hepatocellular damage of
Swiss albino mice has been investigated . -
pubmed
We also observed the dose - dependent
antihepatotoxic effect of the extraction on these
mice . -
pubmed
Novel
hypotensive agents from
Verbesina caracasana . -
pubmed
Caracasandiamide , a second
hypotensive agent isolated from
Verbesina caracasana , is the
cyclobutane dimer (
truxinic type ) of the previously reported
1 -[( 3 , 4 - dimethoxycinnamoyl ) amino ]- 4 -[( 3 - methyl-2 - butenyl ) guanidino ] butane (
caracasanamide ) ( Delle Monache , G. ; et al . -
pubmed
Caracasandiamide , assayed by the iv route in anesthetized
rats at doses ranging from 50 to 3200 microgram / kg of
body weight , was found to have no appreciable effect on heart rate . -
pubmed
This retrospective review examined the cause , level of pathology , onset of symptoms , time taken to treatment , and outcome of 19
patients with
cauda equina syndrome (
CES ) . -
pubmed
Bladder dysfunction was observed in 19/19
patients , with 12/19 regarded as having significant impairment . -
pubmed
Of the five
patients identified as having a poor overall outcome , all five presented with a significant
sphincter disturbance and 4/5 were left with residual
sphincter dysfunction . -
pubmed
Value of the lymphoblastic transformation in
patients with
silicosis . -
pubmed
A 55 - year - old
man with
diabetes mellitus was sick with
shivering ,
abdominal pain and
Escherichia coli in blood and urine cultures ; a 40 - year - old woman with
asthmatic bronchitis had
abdominal pain and
anaemia . -
pubmed
In the
woman , a calculus obstructed the pyelo - ureteral passage ; the resected kidney contained a
squamous cell carcinoma . -
pubmed
The condition is observed mostly in
patients with
diabetes mellitus or
obstruction of the urinary tract . -
pubmed
[ Identification of
Escherichia coli and coliforms in childhood
urinary sepsis using CROMOCEN CC chromogenic - fluorogenic medium ] . -
pubmed
In the last few years , the use of chromogenic and fluorogenic reactions for the identification of the most important pathogens in
human urinary tract infections has became a powerful tool in clinic diagnostic . -
pubmed
Inactivation of the
human androgen receptor gene is associated with
CpG hypermethylation in
uterine endometrial cancer . -
pubmed
Impaired endothelium - dependent vasodilatation in
renal failure in
humans . -
pubmed
BACKGROUND : The main causes of
death in
patients with
chronic renal failure (
CRF ) are
cardiovascular complications . -
pubmed
The aim of the present study was to compare endothelium - dependent vasodilatation ( EDV ) in
patients with
chronic renal failure with a control population controlling for
hypertension ,
diabetes mellitus and
hypercholesterolaemia . -
pubmed
METHODS : Fifty - six
patients with moderate
CRF ( mean
creatinine clearance 29.4 ml / min/1.73 m(2 ) ) underwent evaluation of EDV and endothelium - independent vasodilatation ( EIDV ) by means of forearm blood flow ( FBF ) measurements with
venous occlusion plethysmography during local intra - arterial infusions of
methacholine (
Mch , 2 and 4 microg / min evaluating EDV ) and
sodium nitroprusside (
SNP , 5 and 10 microg / min evaluating EIDV ) . -
pubmed
Fifty - six control
subjects without
renal impairment underwent the same investigation . -
pubmed
RESULTS : Infusion of Mch increased FBF significantly less in
patients with
renal failure than in controls ( 198 vs 374 % , P<0.001 ) , whereas no significant difference was seen regarding the vasodilatation induced by
SNP ( 278 vs 269 % ) . -
pubmed
CONCLUSIONS :
Patients with moderate
CRF have an impaired EDV even after correction for traditional cardiovascular risk factors and this impairment is related to the degree of
renal failure . -
pubmed
Plasmodium malariae -- a case of
quartan malaria in Assam . -
pubmed
Recent clinical results on
patients treated with beta - emitting
32P stents suggest that radiation reduces in - stent
restenosis but may exacerbate neointimal growth at the edges of the stents . -
pubmed
We set up a randomized , double - blind , placebo - controlled trial to study the effectiveness of a topical
corticosteroid agent --
fluticasone propionate aqueous nasal spray ( FPANS ) in
patients with
CRS . -
pubmed
Mycobacterium avium subspecies paratuberculosis is a cause of
Crohn ' s disease . -
pubmed
The administration of many chemo - radiotherapy regimens in
patients with
cancer may be complicated by toxicities that limit the clinicians ' abilities to deliver the most effective doses of active agents . -
pubmed
Oral
mucositis is a major dose - limiting toxic effect and the most important cause of morbidity in
patients undergoing chemo - radiotherapy for
head and neck cancers , in
patients undergoing bone marrow transplantation and those receiving certain chemotherapeutic agents for a variety of
human malignancies . -
pubmed
The intent of this paper is to review preventive strategies and treatment approaches for
patients with established
oral mucositis . -
pubmed
Current studies and our increasing understanding of the etiology and pathogenesis of
oral mucositis will lead to new approaches to the management and improved quality of life for these
patients . -
pubmed
[ Doppler investigation of blood flow in uterine vessels of
patients with
endometrial cancer ] . -
pubmed
BACKGROUND :
Sotalol is used in certain pediatric
patients to treat , suppress , or prevent the
recurrence of life - threatening
ventricular arrhythmias . -
pubmed
Human functional magnetic resonance imaging and magnetoencepholography data strongly suggest that
aura is caused by cortical spreading
depression . -
pubmed
Mitochondrial dysfunction has been suggested by a low
phosphocreatine : Pi ratio and a possible response by
migraine patients to
riboflavin prophylaxis . -
pubmed
Inhalation exposure to
methylene chloride does not induce systemic
immunotoxicity in
rats . -
pubmed
Routine experience of the
mouse - protection assay of
pertussis vaccine . -
pubmed
Experimental
infection of the hemipteron
Oncopeltus fasciatus with trypanosomatidae isolated from other hosts . -
pubmed
After 110 months 83 % of
patients had
recurrence - free disease in M+ , whereas in M- only 40 % of
patients were
recurrence - free . -
pubmed
[ Relation of
asthenopia and some ophthalmological , neuropsychological , and musculoskeletal parameters in
workers assigned to video display terminals ] . -
pubmed
[ Treatment for
hypertensive patients with
diabetes mellitus ] . -
pubmed
Diabetes mellitus doubles the risk of
cardiovascular diseases , even in
hypertensive patients who are already at high risk because of their
high blood pressure . -
pubmed
Of these
patients , final pathology revealed
focal nodular hyperplasia in 4
patients . -
pubmed
The remaining 2
patients , who had
adenoma , were found to harbor
malignancy within the surgical specimens . -
pubmed
In four clinical trials in mostly chemotherapy - naive
patients with
metastatic melanoma ,
paclitaxel was found to be effective with a response rate of 16 % . -
pubmed
In vitro studies have shown that following exposure of
cancer cells to
paclitaxel for 1 h , sensitivity to repeat
paclitaxel doses decreased markedly at 48 - 72 h and returned at 120 h. In this phase II study we assessed the efficacy of
paclitaxel at a dose of 90 mg / m per day given intravenously over 80 min on days 1 , 5 and 9 every 3 weeks , initially in two groups of 14
patients with metastatic choroidal and
non - choroidal melanoma . -
pubmed
One
patient in the
non - choroidal melanoma group had a confirmed response , and 23 additional
patients were therefore accrued to this group . -
pubmed
We observed & gt;50 %
tumour regression in six
patients . -
pubmed
All the responses except one were amongst the 32 evaluable
patients with
non - choroidal melanoma . -
pubmed
OBJECTIVE : We aimed at investigating the relationship between
Helicobacter pylori infection and in vivo lipid peroxidation and platelet activation , as reflected by urinary
8 - iso - prostaglandin ( PG ) F ( 2alpha ) and
11 - dehydro - thromboxane ( TX ) B2 , respectively , in otherwise healthy
dyspeptic subjects . -
pubmed
METHODS AND RESULTS : We measured urinary
8 - iso - PGF2alpha and
11 - dehydro - TXB2 excretion in 40
dyspeptic subjects with a positive
13C - urea breath test and 38
dyspeptic individuals with a negative test . -
pubmed
The arterial circle of Willis of the
mouse helps to decipher secrets of
cerebral vascular accidents in the
human . -
pubmed
Thus , it is conceivable that the
human tendency to develop
cerebral vascular accidents (
CVAs ) might represent a disease of hominization . -
pubmed
Thus , anatomical findings and possibly functions of the arterial circle of
Willi may vary from one
species to another , depending on one 's specific cerebral evolution . -
pubmed
Indirect voiding urosonography for detecting
vesicoureteral reflux in
children . -
pubmed
Among 57 children ( 45
girls and 12
boys , aged 2.7 to 12.0 years ) admitted for echo - enhanced VUS either as part of routine evaluation after
urinary tract infection (
UTI ) or follow - up of a previously detected
VUR , IVUS was also successfully performed in 47 children . -
pubmed
METHODS AND RESULTS : Five
strains of
Bifidobacterium were analysed for their
carbohydrate preference from 12 substrates . -
pubmed
In vitro characterization of the
human biotransformation pathways of
aplidine , a novel marine anti -
cancer drug . -
pubmed
Analysis of fertility indices of
cows with
reproductive disorders and of normal
cows in herds with low and normal fertility . -
pubmed
In 16,910
cows , conception rates to first AI in
cows with
reproductive disorder were & gt;50 % below those in normal
cows ( P<0.001 ) . -
pubmed
Since a sizeable percentage of normal
cows can be identified , reproducing normally under identical management conditions ,
cows in both kinds of herds with
reproductive disorder must be less resistant to environmental stress . -
pubmed
Thus , while
cows with
reproductive disorders maintained their general health and their high level of productivity , they responded either immediately with
uterine disturbances or they refused to cycle properly , and they conceived later . -
pubmed
In vivo imaging of hepatic
fatty acid metabolism in
patients with
non - alcoholic steatohepatitis using semiquantitative
123I - labeled branched - chain fatty acid analog . -
pubmed
Rats were pre - exposed to the footshock chamber ( context ) and
shock stimulus was used unconditioned stimulus . -
pubmed
During re - exposure to context , conditioned
rats spent 80 % of the session in freezing while non - conditioned
rats ( no
shock group ) spent less than 15 % of the session time in freezing . -
pubmed
METHODS AND MATERIALS : Between January 2001 and February 2006 , 59
patients with locally advanced or unfavorably located
choroidal melanoma were enrolled in a Phase I / II clinical trial of
carbon - ion radiotherapy at the National Institute of Radiologic Sciences . -
pubmed
The primary endpoint of this study was normal tissue morbidity , and secondary endpoints were local
tumor control and
patient survival . -
pubmed
RESULTS : Twenty - three
patients ( 40 % ) developed
neovascular glaucoma , and three underwent enucleation for
eye pain due to elevated intraocular pressure . -
pubmed
Five
patients had died at analysis , three of distant
metastasis and two of concurrent disease . -
pubmed
All but one
patient , who developed marginal
recurrence , were controlled locally . -
pubmed
Six
patients developed distant
metastasis , five in the liver and one in the lung . -
pubmed
The current study examined the potential benefits of self - generation on learning and memory in
individuals with
traumatic brain injury (
TBI ) and
multiple sclerosis (
MS ) . -
pubmed
Subjects consisted of 18
individuals with
TBI and 31
individuals with clinically definite
MS . -
pubmed
METHODS : One hundred eighty - two ( 182 )
patients with
DSM - IV bipolar I disorder were longitudinally investigated ( approximately 17 years duration of the illness ) with standardized instruments . -
pubmed
According to that dominance , the
patients were divided into three groups ( mood - dominated , schizo - affective - dominated ,
schizophreniform - dominated ) , and these groups were compared to each other at various levels . -
pubmed
Here we describe a 52 year old
woman admitted with
chest pain and ST elevation with mildly increased cardiac enzymes . -
pubmed
The purpose of this study was to evaluate the size responses and vascular responses to three different sizes of Embosphere ( EMBS ) embolization particles used for chemo - embolization in
patients with unresectable
hepatocellular carcinoma (
HCC ) . -
pubmed
Forty - seven
patients with biopsy proven
HCC treated with TACE using EMBS ( Biosphere Medical , Rockland , MA , USA ) were included in this study . -
pubmed
We demonstrate the use of such an approach in estimating the number of people
infected with the hepatitis C virus (
HCV ) in England and Wales . -
pubmed
[ Light therapy : its effectiveness in treating
insomnia in elderly
patients ] . -
pubmed
Cord blood - derived
human MSCs were exposed to in vitro conditions simulating in vivo environments of the beating heart with acute
ischemia , as follows : ( a ) myocardial proteins or serum obtained from sham - operated
rats , and ( b ) myocardial proteins or serum from
AMI rats , with or without application of oscillating pressure . -
pubmed
The pathophysiologic significance of in vitro results was confirmed using the
rat AMI model . -
pubmed
Composting has been used for disposal of poultry carcasses and manure following outbreaks caused by
avian influenza virus ( AIV ) and
Newcastle disease virus (
NDV ) , but methods are needed to test for survival of the viruses in compost to ensure biosecurity . -
pubmed
We have previously reported that 50 % of
patients with
sudden sensorineural hearing loss (
SNHL ) show high signals in the affected inner ear on 3D - FLAIR MRI . -
pubmed
STUDY DESIGN AND METHODS : We used 3D - FLAIR at 3 Tesla with and without
gadolinium enhancement to evaluate the pathologic conditions in the inner ears of 48
patients with sudden
SNHL . -
pubmed
RESULTS : Thirty - one of 48
patients with sudden
SNHL showed high signals in the affected inner ear on precontrast 3D - FLAIR . -
pubmed
In this case , we report on a pregnant
woman who was diagnosed with
non - small - cell lung cancer and received therapy with
paclitaxel and
cisplatin . -
pubmed
METHODS : To study the formation of functional filtration
bleb after trabeculectomy , the result of trabeculectomy with the limbus based conjunctival flap in 165 eyes and the fornix based conjunctival flap in 207 eyes ( 372 eyes in 372
cases with primary
glaucoma in total ) was compared . -
pubmed
In
patients with trabeculectomy using the limbus based conjunctival flap , the success rate of the formation of the filtration
bleb was 83.03 % in 1 week and 78.69 % in three months postoperatively , while in those using the fornix based conjunctival flap , the success rate was 55.07 % in 1 week and 53.03 % in 3 months . -
pubmed
OBJECTIVE : To assess whether complementary and alternative medicine ( CAM ) use is associated with the timing of highly active antiretroviral therapy ( HAART ) initiation among
human immunodeficiency virus ( HIV )- infected participants of the Women 's Interagency
HIV Study . -
pubmed
Prognostic significance of
myocardial ischemia by
dobutamine stress echocardiography in
patients without
angina pectoris after coronary revascularization . -
pubmed
The clinical utility of stress testing in
patients without
angina pectoris after revascularization has been questioned . -
pubmed
Idiopathic intracranial hypertension after 40 years of age : clinical features in 23
patients . -
pubmed
The aim of this study is to investigate the clinical features of
IIH in
patients older than 40 years . -
pubmed
METHODS : This is a retrospective chart review ( 1998 - 2007 ) of all consecutive
patients older than 40 years who were diagnosed with
IIH based on the Modified Dandy Criteria . -
pubmed
RESULTS : Twenty three of the 200
IIH patients in the institutional database fulfilled study entry criteria . -
pubmed
Coexisting
systemic arterial hypertension was found in 13 ( 56.5 % )
patients . -
pubmed
The most common presenting symptoms were visual ; mainly
blurred vision and transient
visual obscuration ( 15/17
patients , 88.23 % ) . -
pubmed
Eleven
patients ( 64.7 % ) complained of
headache , and another 4 ( 23.5 % ) of pulsatile intracranial noise . -
pubmed
Indoor allergen exposure to sources such as house - dust mites ,
pets ,
fungi , and insects plays a significant role in patients with
allergic rhinitis and
asthma . -
pubmed
METHODS : A prospective double - blind randomised placebo - controlled crossover trial of
phenylalanine - restricted diet was performed in a group of 34
adults ( aged 21 - 61 years , median 49 ) with late diagnosed
PKU with severe challenging behaviour . -
pubmed
Twenty years after the onset of
diabetes , almost all
patients with
type 1 diabetes and over 60 % of
patients with
type 2 diabetes will have some degree of
retinopathy . -
pubmed
Predictors of nonresponse to
lactulose for minimal
hepatic encephalopathy in
patients with
cirrhosis . -
pubmed
BACKGROUND / AIMS : Minimal
hepatic encephalopathy (
MHE ) impairs health - related quality of life and predicts overt
hepatic encephalopathy (
HE ) in cirrhotic
patients . -
pubmed
RESULTS : Sixty
patients ( 54.5 % ) were diagnosed as having
MHE : 17/39 ( 44 % ) in Child 's A , 21/42 ( 50 % ) Child 's B and 22/29 ( 76 % ) in Child 's C. There was a significant difference between Child 's C 's vs Child 's A 's and B 's ( P<0.05 ) . -
pubmed
Of 60
patients with
MHE , after treatment , psychometry remained abnormal in 22 ( 36.6 % ) and P300ERP in 21 ( 35 % )
patients . -
pubmed
CONCLUSION : The prevalence of
MHE was 55 % and
MHE improved in 57 %
patients with
lactulose . -
pubmed
BACKGROUND AND PURPOSE :
Patients with chronic
visual field defects typically show a contralesional line bisection error ( LBE ) . -
pubmed
METHODS : Twenty - two
patients with
visual field defects due to
stroke without
neglect were tested for line bisection and for the anatomic lesion site by voxelwise lesion - behavior mapping analysis . -
pubmed
RESULTS :
Patients with
visual field defects in the acute and chronic phases differed in neither the direction nor the extent of their LBE . -
pubmed
INTRODUCTION : Conventional imaging ( CI ) is known to have limitations with respect to staging of
patients with primary or relapsed
prostate cancer . -
pubmed
METHODS : Sixteen
prostate cancer patients were evaluated ( 7 for staging and 9 for restaging ) . -
pubmed
CONCLUSION : FCH - PET / CT has the potential to impact on the management of
patients with
prostate cancer significantly more often than CI . -
pubmed
BACKGROUND : In
patients with various autoimmune and
rheumatic diseases , a drug - induced
lupus - like syndrome (
DILS ) has been reported with the use of
adalimumab ,
cerrolizumab pegol ,
etanercept , and
infliximab . -
pubmed
MATERIALS AND METHODS : We describe a 62 - year - old
woman with
rheumatoid arthritis who developed a pruritic photo - distributed
rash two months after the initiation of
etanercept therapy . -
pubmed
RESULTS : In our study , all
patients were having
bilateral nasal polypi . -
pubmed
A number of novel
pyrrole [ 1,2 - a ] pyrazine derivatives were synthesized and evaluated in in vivo
animal models of
epilepsy . -
pubmed
Obese men participated in an 8 - week low - intensity training program without concomitant diet . -
pubmed
At baseline ,
obese men showed
diastolic dysfunction on standard echocardiography , lower
strain values ( systolic
strain : 15.9 + - 0.9 vs. 18.8 + - 0.3 % , diastolic
strain rate : 0.81 + - 0.09 vs. 1.05 + - 0.06 s(-1 ) ) , and significant
intraventricular dyssynchrony ( systolic : 13.3 + - 2.1 vs. 5.4 + - 2.1 ms , diastolic : 17.4 + - 3.2 vs. 9.1 + - 2.1 ms ) ( P & lt ; 0.05 vs. controls for all variables ) . -
pubmed
A randomized , double - blind , placebo - controlled pilot study to assess the ability of
rifaximin to prevent recurrent
diarrhoea in
patients with
Clostridium difficile infection . -
pubmed
BACKGROUND : Uncontrolled case series have demonstrated decreased
Clostridium difficile infection (
CDI )
recurrence in
patients given
rifaximin after standard antibiotic therapy . -
pubmed
However , clinical trials assessing whether
rifaximin decreases recurrent
diarrhoea in
patients with
CDI have not been performed . -
pubmed
The purpose of this study was to assess rates of recurrent
diarrhoea in
patients with
CDI given
rifaximin versus placebo immediately after standard therapy . -
pubmed
Patients with
CDI and a Horn 's index & gt;=1 were randomized to receive
rifaximin 400 mg three times daily or placebo for 20 days given immediately after finishing standard anti - CDI antibiotics . -
pubmed
Patients were followed for 3 months and assessed for recurrent
diarrhoea that included
CDI recurrence ( return of
diarrhoea with a positive toxin test ) and patient self - reported return of non - CDI
diarrhoea after a period of wellness . -
pubmed
Recurrent
diarrhoea occurred in 17 of 35 ( 49 % )
patients given placebo and 7 of 33 ( 21 % ) given
rifaximin ( P = 0.018 ) . -
pubmed
CDI recurrence occurred in 11 of 35 ( 31 % )
patients given placebo and 5 of 33 ( 15 % ) patients given
rifaximin ( P = 0.11 ) . -
pubmed
CONCLUSIONS :
Patients with
CDI given a
rifaximin chaser regimen experienced a decreased incidence of recurrent
diarrhoea compared with placebo . -
pubmed
Effects of
glutamine supplementation on oxidative stress - related gene expression and antioxidant properties in
rats with
streptozotocin - induced
type 2 diabetes . -
pubmed
These results suggest that dietary
GLN supplementation decreases oxidative stress - related gene expression , increases the antioxidant potential and may consequently attenuate
renal oxidative damage in
rats with
STZ - induced
diabetes . -
pubmed
BACKGROUND : There are no clear recommendations to guide posttreatment surveillance in
patients with
pancreatic cancer . -
pubmed
Our goal was to describe the posttreatment surveillance patterns in
patients undergoing curative - intent resection for
pancreatic cancer . -
pubmed
BACKGROUND : The
cat , considered the main reservoir of
Microsporum canis , lives in urban areas , and also plays an important role in the emergence of
dermatomycoses . -
pubmed
A total of 45 samples from
cats with and without
dermatological lesions were analysed . -
pubmed
Mycoplasma hyosynoviae is a common agent responsible for
polyarthritis leading to decreased production in swine herds worldwide . -
pubmed
Antimicrobial agents are used to combat
infections ; however breakpoints for
M. - pubmed
A dry microbroth dilution method was conducted to compare the minimum inhibitory concentrations ( MICs ) for 18 antibiotics , representative of different classes , against 24 recent isolates ( 23 field isolates and the type
strain ) of
M. - pubmed
STUDY DESIGN AND SETTING : Prospective cohort study of 602 newly diagnosed
prostate cancer patients recruited from an urban academic hospital and a Veterans Administration hospital . -
pubmed
METHODS : Consecutive
patients with
high myopia ( & gt;=6 diopters [ D ] ) with no other pathology such as lacquer cracks in the fovea ,
choroidal neovascularization , or
myopic macular schisis , were evaluated . -
pubmed
RESULTS : The New York cohort was composed of 35 eyes of 25
patients who had a mean age of 57 years ( standard deviation , + -18.1 years ) and a mean
refractive error of -10.9 D ( + -3.6 D ) . -
pubmed
The Japanese cohort was composed of 110 eyes of 61
patients who had a mean age of 46.8 years ( + -14.7 years ) and a mean
refractive error of -9.2 D ( + -3.1 D ) and a mean axial length of 27 mm ( + -1.4 mm ) . -
pubmed
[ Late
renal artery stent thrombosis treated with aspiration trombectomy in a
patient with
renal insufficiency and
renal hypertension ] . -
pubmed
METHODS AND RESULTS : A total of 652
patients with stable
CAD were studied . -
pubmed
RESULTS : During 1990 - 1991 , 14 538
children were identified with
respiratory infections and
bronchiolitis was diagnosed in 519/14 538
children ( 3.56 % ) . -
pubmed
Tobacco use leads to numerous health problems , including
cancer ,
heart disease ,
emphysema , and
stroke . -
pubmed
We report a case of multiple
cutaneous atypical leiomyomas occurring in a 43 - year - old
man with long history of lesions of the right lower leg and a family history of
leiomyomatosis . -
pubmed
Duration of antiresorptive effects of low - dose
zoledronate in
osteopenic postmenopausal
women : a randomized , placebo - controlled trial . -
pubmed
A total of 180 postmenopausal
women with
osteopenia enrolled in a double - blind , randomized , placebo - controlled trial over 2 years at an academic research center . -
pubmed
Weight reduction improves nocturnal respiration in
obese sleep apnoea patients - A randomized controlled pilot study . -
pubmed
SUMMARY : OBJECTIVES : Randomized controlled pilot study of the effect of
weight reduction on nocturnal respiratory parameters in obese
patients with
obstructive sleep apnoea syndrome (
OSAS ) . -
pubmed
CONCLUSIONS : This pilot study indicates that
weight reduction improves nocturnal respiration in obese
OSAS patients after 3 months ' dietary treatment compared to expectancy . -
pubmed
BACKGROUND : Over the past years , Q
fever has become a major public health problem in the Netherlands , with a peak of 2,357
human cases in 2009 . -
pubmed
In the first instance , Q
fever was mainly a local problem of one province with a high density of large dairy
goat farms , but in 2009 an alarming increase of Q
fever cases was observed in adjacent provinces . -
pubmed
RESULTS : Overall , public perceptions and behaviors regarding Q
fever were consistent with the trends over time in the numbers of new
human Q
fever cases in different epidemiological regions and the amount of media attention focused on Q
fever in the Netherlands . -
pubmed
Preoperative pulmonary rehabilitation in
patients with
non - small cell lung cancer and
chronic obstructive pulmonary disease . -
pubmed
INTRODUCTION : The aim of this study was to assess the effects of preoperative pulmonary rehabilitation ( PPR ) on preoperative clinical status changes in
patients with
chronic obstructive pulmonary disease (
COPD ) and
non - small cell lung cancer (
NSCLC ) , and net effects of PPR and
cancer resection on residual pulmonary function and functional capacity . -
pubmed
MATERIAL AND METHODS : This prospective single group study included 83
COPD patients ( 62 + -8 years , 85 %
males , FEV1 = 1844 + -618 ml , Tiffeneau index = 54 + -9 % ) with
NSCLC , on 2 - 4 - week PPR , before resection . -
pubmed
CONCLUSIONS : Preoperative pulmonary rehabilitation significantly enhances clinical status of
COPD patients before
NSCLC resection . -
pubmed
Subsequent testing of donations positive in
Treponema pallidum hemagglutination assay included
Venereal Disease Research Laboratory and fluorescent Treponemal antibody absorption . -
pubmed
Coinfection with
HIV ,
HCV , and
HBV was calculated as 8 % , 1.88 % , and 0.37 % for positive donations , respectively . -
pubmed
A 12 - year - old
boy presented with a 6 - month history of
hip pain . -
pubmed
Tuberculosis in
HIV patient . -
pubmed
Bone
metastases are often observed in
patients with
lung cancer ,
kidney cancer ,
breast cancer ,
myeloma , and
prostate cancer . -
pubmed
Autologous engineered skin substitutes ( ESS ) have been shown to close excised , full - thickness
burns , but are consistently hypopigmented due to depletion of
human melanocytes ( hM ) during culture of keratinocytes . -
pubmed
To evaluate this risk , 16
strains of hM were isolated and propagated in selective culture medium , then injected subcutaneously into
athymic mice ( 1 x 10(7 ) hM / animal ; n = 6 /
strain ) and followed for 24 weeks . -
pubmed
Human melanoma cells (
SK - Mel-2 ,
SK - Mel-5 ) served as positive controls . -
pubmed
In contrast ,
SK - Mel-2 formed
tumors in 50 % of
mice , and
SK - Mel-5 formed
tumors in 83 % of
mice . -
pubmed
PURPOSE OF REVIEW : Cardiac
patients are a fast emerging population vulnerable to
gastrointestinal bleeding (
GIB ) due to their use of antithrombotic medications . -
pubmed
This review will quantify the
GIB risk of cardiac
patients prescribed antithrombotic medications , summarize risk - management strategies and highlight knowledge gaps . -
pubmed
We report that up to 49 of the 232 monogenic etiologies ( 21 % ) of
human primary immunodeficiencies (
PIDs ) were initially reported in single patients . -
pubmed
When supported by satisfaction of rigorous criteria , the report of single patient - based discovery of
Mendelian disorders should be encouraged , as it can provide the first step in the understanding of a group of
human diseases , thereby revealing crucial pathways underlying physiological and
pathological processes . -
pubmed
Yet , current treatments targeting serotonergic and
noradrenaline reuptake systems are insufficient to provide long - term relief from
depressive symptoms in most
patients , indicating the need for new treatment targets . -
pubmed
A sample from
periodontal pocket was extracted to identify
Porphyromonas gingivalis (
Pg ) ,
Treponema denticola (
Td ) ,
Tannerella forsythia ( Tf )
Prevotella intermedia ( Pi ) and
Agreggatibacter actinomycemcomitans ( Aa ) . -
pubmed
CLINICAL FEATURES : A 48 - year - old white
man presented to a chiropractic clinic with a complaint of left lateral elbow
pain that began 2 years previous with insidious onset . -
pubmed
The
patient reported an inability to play 18 consecutive holes of golf due to the
pain . -
pubmed
Significance of oral
glucose tolerance tests in
non - alcoholic fatty liver disease patients with a fasting plasma
glucose level of & lt;126 mg / dL and HbA1c level of & lt;= 6.4 % in Japan . -
pubmed
OBJECTIVE : The aim of this study was to clarify the indications for oral
glucose tolerance tests ( OGTT ) in
non - alcoholic fatty liver disease (
NAFLD )
subjects with a HbA1c level of & lt;=6.4 % , fasting plasma
glucose ( FPG ) level of & lt;126 mg / dL and no history of
diabetes . -
pubmed
PATIENTS : A total of 569
NAFLD subjects underwent 75 - g OGTT . -
pubmed
RESULTS : The prevalence of
diabetes on the OGTT was 7.7 % ( 44/569 ) among the
NAFLD patients with an HbA1c level of & lt;=6.4 % , FPG level of & lt;126 mg / dL and no history of
diabetes . -
pubmed
Factor structure and psychometric properties of the TFEQ in morbid
obese patients , candidates to bariatric surgery . -
pubmed
METHODS : Immune - activating properties of MPLA and LPS were compared in
human monocytes and mast cells ( MCs ) , a
mouse endotoxin
shock model ( ESM ) , and
mouse bone marrow ( BM)-derived myeloid dendritic cells ( mDCs ) , T cells ( TCs ) , B cells , and MCs . -
pubmed
RESULTS : The most common clinical
syndrome in these 42
patients was
chronic cholecystitis , followed by
acute cholecystitis . -
pubmed
PURPOSE : In this phase I study , single - agent chemotherapy was conducted in
patients with locoregionally advanced
nasopharyngeal carcinoma (
NPC ) using
nedaplatin (
NDP ) and concomitant radiotherapy . -
pubmed
CONCLUSION :
NDP combined with radiotherapy and administered every 21 days for three cycles was active in
patients with locoregionally advanced
NPC . -
pubmed
METHODS : We identified 8427 patients in Surveillance , Epidemiology , and End Results ( SEER ) with
nonmetastatic oropharyngeal cancer with unknown
HPV - status diagnosed from 2004 to 2008 . -
pubmed
We present two cases of
congenital intrahepatic portosystemic shunts in which the right portal vein directly communicated with the inferior venacava ( IVC ) in one
patient and with the hepatic vein in the other . -
pubmed
Multiple hepatic nodules consistent with
focal nodular hyperplasia (
FNH ) were seen in the first
patient . -
pubmed
The second
patient presented with recurrent history of
hepatic encephalopathy . -
pubmed
Chemotherapy for
Adults with
Malignant Glioma : A Systematic Review and Network Meta - Analysis . -
pubmed
To compare the efficacy of common therapies , we performed network meta - analysis to estimate the efficacy and safety among
procarbazine ,
lomustine ,
vincristine ,
temozolomide ,
bevacizumab plus
temozolomide , and placebo for
patients with
malignant glioma . -
pubmed
The primary endpoint of the analysis was the overall survival ( OS ) and progression - free survival ( PFS ) of
glioma patients . -
pubmed
CONCLUSION :
Bevacizumab plus
temozolomide combination therapy is not significantly more effective than
temozolomide alone in improving survival of
glioma patients . -
pubmed
Bevacizumab should be used with caution in
glioma patients . -
pubmed
EXPERT OPINION :
Ospemifene is efficacious for improving
vaginal dryness or
dyspareunia as the
patient - identified most bothersome symptom , and Phase III clinical trials ( 4648
patients ) have shown good efficacy in terms of improvement of objective and subjective signs and measures of GSM in postmenopausal
women . -
pubmed
A 67 - year - old
man presented with labile
hypertension and
orthostatic hypotension after radical neck dissection and radiotherapy for
squamus cell carcinoma . -
pubmed
Our findings have implications for the use of
mouse models to assess
bone marrow toxicity for DNA - damaging agents and inhibitors of the DNA damage response . -
pubmed
METHODS : A bioglue - coated
Teflon sling was crafted by the surgeon and applied to
patients in whom
neurovascular compression was caused by the VA . -
pubmed
Neither
recurrence nor postoperative
neurological deficit was noted during the 2 - year follow - up , except in one
patient who developed permanent
deafness . -
pubmed
Parametrial involvement in
women with low - risk , early - stage
cervical cancer . -
pubmed
This study identified the incidence of parametrial involvement in low risk , early - stage
cervical cancer patients and evaluated the factors associated with parametrial involvement . -
pubmed
Patients with
squamous cell carcinoma or
adenocarcinoma grade 1 - 2 ,
tumour size less than 2 cm , no lymphovascular space invasion ( LVSI ) , negative pelvic nodes and depth of stromal invasion ( DSI ) less than 10 mm were identified as the low - risk group . -
pubmed
Most
patients ( 81.5 % ) had
tumour size less than 2 cm . -
pubmed
Thirteen
patients ( 5.3 % ) had parametrial involvement , 77 ( 31.7 % ) had
DSI more than 10 mm , 121 ( 49.8 % ) had more than 50 % invasion , 119 ( 49 % ) had
LVSI and 19 ( 7.5 % ) had node
metastasis . -
pubmed
A comparison with a matched population of
patients with
femoroacetabular impingement . -
pubmed
PURPOSE : To prospectively compare defects of the articular cartilage and labrum in asymptomatic
volunteers and in
patients with
femoroacetabular impingement (
FAI ) matched for age and gender . -
pubmed
A total of 14 % of
volunteers had
acetabular cartilage defects , and 6 % had
femoral cartilage defects , compared with 47 % and 30 % in symptomatic
patients ( P & lt;= 0.001 and P & lt;= 0.003 ) , respectively . -
pubmed
Labrum defects were seen in 44 % of volunteers versus 61 % of
patients ( P & lt;= 0.12 ) . -
pubmed
CONCLUSION : A substantial number of asymptomatic
volunteers had
labral tears ,
defects of the acetabular cartilage , and to a lesser degree , defects of the femoral cartilage ; our data demonstrate that not all cartilage and labral defects of the hip joint are symptomatic and that a similar predilection for location of defects is found in volunteers and
FAI patients . -
pubmed
Post - Anoxic Reticular Reflex
Myoclonus in a
Child and Proposed Classification of Post - Anoxic
Myoclonus . -
pubmed
PATIENT DESCRIPTION : A nine - year - old
boy with severe
hypoxic - ischemic encephalopathy due to submersion developed early
epileptic spasms followed by stimulus sensitive multifocal generalized
myoclonus and later
dystonia . -
pubmed
CONCLUSIONS : Reticular reflex
myoclonus can be demonstrated by detailed neurophysiological assessment in
children as in
adults , and it has a similar poor prognosis in
children . -
pubmed
Aortoiliac occlusive disease (
AIOD ) is widely prevalent and leads to significant limitations in
patient quality of life . -
pubmed
hydrophila recovered from
Nile tilapia exhibiting disease and mortality after exposed to transport - induced stress and subsequently confirmed their virulence in artificial
infection . -
pubmed
Experimental
infection revealed that the high dose of
A. - pubmed
Here , we present a 56 - year - old
man with
pancreatic SCC . -
pubmed
However , routine vaccines for the world 's major
human parasitic diseases do not yet exist . -
pubmed
We performed a real - life study on topical therapies in
psoriasis and observed a variation in the amounts of ointment
patients applied during the study . -
pubmed
CONCLUSIONS : We look forward to seeing whether the current pressure to improve
psoriasis treatment leads to more
patients receiving systemic therapies or to better adherence to , and persistence with , topical therapies . -
pubmed
CONCLUSION : Metastatic , castration - resistant
prostate cancer is a discrete and different phase of
prostate cancer with newer agents that have shown great promise in controlling the disease and offering a survival benefit for
patients . -
pubmed
Venous invasion by
hepatic tumors most commonly occurs with
hepatocellular carcinoma and is associated with worse
patient prognosis . -
pubmed
Research has shown that the process of sensory gating is disrupted in
patients suffering from clinical disorders including
attention deficit hyper activity disorder ,
schizophrenia , and
Alzheimer ' s disease . -
pubmed
Infarct size were measured in isolated male
Sprague - Dawley rat Langendorff perfused hearts treated for 125 min with
Sunitinib in the presence and absence of
NQDI-1 . -
pubmed
Sunitinib significantly decreased the cell viability of
human acute myeloid leukemia 60 cell line (
HL60 ) . -
pubmed
METHODS : Eight - nine
MDS patients(
MDS group ) and 20
persons without
hematologic disease as controls(Control group ) were enrolled . -
pubmed
These findings may partially explain the cause of hematopoietic stem cell malignant clone in
MDS patients . -
pubmed
[ Analysis of effect of prevention and control technique training of
human important
parasitic diseases in Jiangsu Province in 2017 ] . -
pubmed
OBJECTIVE : To evaluate the effect of the prevention and control technique training of
human important
parasitic diseases for basic professional and technical personnel in Jiangsu Province in 2017 . -
pubmed
Patients in
cardiogenic shock due to severe failure of a mitral bioprosthesis have extremely high risk for repeat standard cardiac surgery . -
pubmed
We report a successful transseptal mitral valve - in - valve implant performed in a
patient in
cardiogenic shock due to a flail mitral bioprosthesis requiring bridging intravenous inotropic and intra - aortic balloon pump support . -
pubmed
The aim of this study was two - fold : ( i ) to investigate structural and functional brain network architecture in
patients with
Alzheimer ' s disease (
AD ) and
amnestic mild cognitive impairment (
aMCI ) , stratified in converters ( c - aMCI ) and non - converters ( nc - aMCI ) to
AD ; and to assess the relationship between healthy brain network functional connectivity and the topography of
brain atrophy in
patients along the
AD continuum . -
pubmed
Ninety - four
AD patients , 47
aMCI patients ( 25 c - aMCI within 36 months ) and 53 age- and sex - matched healthy controls were studied . -
pubmed
Healthy topological features of brain regions were assessed based on their connectivity with the point of maximal
atrophy ( epicenter ) in
AD and
aMCI patients . -
pubmed
Brain network graph analysis properties were severely altered in
AD patients . -
pubmed
Brain regions most strongly connected with the disease - epicenter in the healthy functional connectome were also the most atrophic in both
AD and c - aMCI
patients . -
pubmed
One - year optical coherence tomography findings in
patients with late and very - late stent
thrombosis treated with intravascular imaging guided percutaneous coronary intervention . -
pubmed
Patients with late / very - late stent
thrombosis (
ST ) are at high risk of recurrent - ST . -
pubmed
None of the
patients had thin - cap
fibroatheroma neoatherosclerosis . -
pubmed
This single center study aimed to characterize
GIST patients in terms of
tumor location , clinical presentation ,
metastasis formation , as well as associated
secondary malignancies . -
pubmed
METHODS : In a retrospective study , 104
patients with a histologically confirmed diagnosis of
GIST , collected between 1993 and 2011 , were characterized for several clinical features . -
pubmed
Although uncommon , congenital
cardiac defects should be considered in
animals presenting with clinical signs of
hypoxemia ,
dyspnea , or failure to thrive . -
pubmed
METHODS : All
patients with
SSc who underwent at least two 6MWT within a minimum 3 - month interval plus simultaneous routine clinical , biological , and functional evaluations were consecutively enrolled in this observational study over 6 years . -
pubmed
CONCLUSION : We show strong reproducibility for the 6MWD and confirm the 6MWT utility to assess the overall prognosis of
patients with
SSc . -
pubmed
Importantly , we find that distinctive dynamic connectivity patterns are spatially associated with Allen
Human Brain Atlas genetic transcription levels of synaptic long - term potentiation and long - term
depression - related genes . -
pubmed
METHODS : 44
patients with
congenital heart defect were enrolled in the study . -
pubmed
Methods : In this double - blind , cluster - randomized trial , villages were randomly allocated ( 1:1 ) for high - coverage vaccination of
children aged 6 months through 10 years with 2008 - 09 northern hemisphere IIV3 or inactivated
polio vaccine ( IPV ) . -
pubmed
Among vaccinees , total effectiveness against illness caused by
seasonal influenza virus ( presumed all drifted
A / H3N2 based on antigenic characterization data ) circulating at high rates among children was 43.6 % ( 95 % CI , 18.6 % to 60.9 % ) . -
pubmed
Total effectiveness against illness caused by pandemic
influenza virus (
A / H1N1pdm09 ) was -52.1 % ( 95 % CI , -177.2 % to 16.6 % ) . -
pubmed
Conclusions : IIV3 provided statistically significant , moderate protection to children in Senegal against circulating pre-2010 seasonal
influenza strains but not against
A / H1N1pdm09 not included in the vaccine . -
pubmed
METHODS : We performed a retrospective analysis of a prospectively held database of all
patients who underwent arterial ligation for infected
femoral pseudoaneurysms due to
chronic intravenous drug abuse from January 2012 to March 2018 . -
pubmed
Information recorded for each
patient included age , gender , blood investigations , microbiologic results , diagnostic modality , operative details , outcome of surgery ,
postoperative complications , and follow - up . -
pubmed
Nine
patients underwent major limb amputation for severe
limb ischemia ( 7 transfemoral amputations and two 53
hip disarticulation ) . -
pubmed
ETHNOPHARMACOLOGICAL RELEVANCE :
Copaiba oleoresin has been used in folk medicine in the treatment of
bronchitis ,
syphilis ,
skin diseases and
ulcers due to its anti - inflammatory and antiseptic activities , but there is no information about major compounds oral absorption to support the traditional use . -
pubmed
Prevalence of
cervical disease at age 20 after immunisation with bivalent
HPV vaccine at age 12 - 13 in Scotland : retrospective population study . -
pubmed
OBJECTIVE : To quantify the effect on
cervical disease at age 20 years of immunisation with bivalent
human papillomavirus (
HPV ) vaccine at age 12 - 13 years . -
pubmed
CONCLUSIONS : Routine vaccination of
girls aged 12 - 13 years with the bivalent
HPV vaccine in Scotland has led to a dramatic reduction in preinvasive
cervical disease . -
pubmed
Development and validation of a real - time RT - PCR assay for the quantification of
rabies virus as quality control of inactivated
rabies vaccines . -
pubmed
Elemental formula is commonly used in
children with
feeding intolerance . -
pubmed
We describe two , medically complex and feeding tube dependent ,
patients exclusively fed with Neocate who subsequently developed
hypophosphatemic rickets . -
pubmed
Cervical cancer develops through persistent
infection with high - risk
human papilloma virus (
hrHPV ) and is a leading cause of
death among women worldwide and in the United States . -
pubmed
Periodic surveillance through
hrHPV and Pap smear - based testing has remarkably reduced
cervical cancer incidence worldwide and in the USA . -
pubmed
BACKGROUND :
Staphylococcus aureus remains a medical challenge in the treatment of
bacterial infections . -
pubmed
Pleomorphic xanthoastrocytoma (
PXA ) is an uncommon , long - term
epilepsy associated
tumor of young
adults . -
pubmed
Larger trials are required to understand long - term efficacy and safety of this medication in various
patient populations and to elucidate its effect on the
pathologic processes underpinning
type 2 diabetes . -
pubmed
The reinforcing effects of drugs mostly depend on
dopamine signaling in the nucleus accumbens , and chronic drug exposure triggers glutamatergic - mediated neuroadaptations in
dopamine striato - thalamo - cortical ( predominantly in prefrontal cortical regions including orbitofrontal cortex and anterior cingulate cortex ) and limbic pathways ( amygdala and hippocampus ) that , in vulnerable
individuals , can result in
addiction . -
pubmed
Methods for generating hypotheses in
human enteric illness outbreak investigations : a scoping review of the evidence . -
pubmed
PATIENT CONCERNS : A 47 - year - old
woman was admitted due to
poor appetite , general
fatigue ,
puffiness of face ,
systemic rash , and
abdominal distension . -
pubmed
On physical examination , the
patient displayed as general
lymphadenopathy ,
splenomegaly ,
hepatomegaly , and shifting
dullness . -
pubmed
Everolimus - associated
cytomegalovirus colitis in a
patient with metastasized
breast cancer : a case report . -
pubmed
PURPOSE : Anti -
cancer therapy put
patients in an immunocompromised status . -
pubmed
METHODS : We present a case of
everolimus - associated
cytomegalovirus colitis on a
patient receiving
everolimus and
exemestane therapy for the treatment of metastasized
breast cancer . -
pubmed
RESULTS : The
patient presented
septic shock and acute
peritonitis at first . -
pubmed
Thus , for solid
cancer patients presented with
fever of unknown origin , clinicians should consider potential complications of
CMV infection . -
pubmed
The most common adverse events were
cataract /
posterior subcapsular opacities in 47 ( 11.03 % )
patients and
conjunctival hemorrhage in 24 ( 5.44 % )
patients . -
pubmed
METHODS : Two 12 - week , Phase 3 , randomized , multicenter , double - blind , vehicle - controlled , 2 - arm studies were performed in
patients with moderate - to - severe
papulopustular rosacea . -
pubmed
RESULTS :
Subjects who received
FMX103 1.5 % , vs vehicle - treated controls , exhibited a significantly greater reduction in the number of
inflammatory lesions ( FX2016 - 11 : -17.57 vs -15.65 ; P=.0031 ; FX2016 - 12 : -18.54 vs -14.88 ; P<.0001 ) and higher rates of Investigator Global Assessment treatment success ( FX2016 - 11 : 52.1 % vs 43.0 % ; P=.0273 ; FX2016 - 12 : 49.1 % vs 39.0 % ; P=.0077 ) . -
pubmed
Genetic improvement in
banana is a challenging task due to its parthenocarpic nature and
triploid genome . -
pubmed
Inosine prevents
hyperlocomotion in a
ketamine - induced model of
mania in
rats . -
pubmed
Evidence shows that
individuals in
manic episodes present a purinergic system dysfunction . -
pubmed
Despite the limitations ,
inosine administration could be a promising candidate for
bipolar disorder treatment , especially by attenuating
maniac phase symptoms , once it was able to prevent the
hyperlocomotion induced by
ketamine in
rats . -
pubmed
ImPlementation REsearCh to DEvelop Interventions for People Living with HIV ( the PRECluDE consortium ): Combatting
chronic disease comorbidities in
HIV populations through implementation research . -
pubmed
Buruli ulcer (
BU ) is a
subcutaneous necrotic infection of the skin caused by
Mycobacterium ulcerans . -
pubmed
It is the third most common
human mycobacterial disease after
tuberculosis (
TB ) and
leprosy . -
pubmed
In addition , the high level of genetic polymorphism of different
strains of
N. - pubmed
METHODS : In this randomized trial with adult
depressed outpatients ( n = 151 ) , we estimated Gaussian graphical models among nine core
MDD symptom - domains before and after 8 weeks of treatment with either
escitalopram or
desvenlafaxine . -
pubmed
KEY POINTS : Early detection and diagnosis of
vertebral fragility fractures (
VFFs ) significantly reduce
patient morbidity and mortality . -
pubmed
Analysis of Risk Factors for Lymph Node Metastases in Elderly
Patients with
Papillary Thyroid Micro - Carcinoma . -
pubmed
Methods : We retrospectively analyzed the clinical data of
thyroid cancer patients admitted to the Head and Neck Surgery Center of Sichuan Cancer Hospital , Chengdu , China , from January 2015 to September 2018 . -
pubmed
Conclusion : 1 ) Preoperative color Doppler ultrasound is not recommended as the basis for cervical lymph node dissection in
PTMC patients . -
pubmed
2 ) For multiple
cancer foci , irregular nodules , and elderly
patients with PTMC extra - thyroidal expansion , we recommend a prophylactic central lymph node dissecting . -
pubmed
3 ) Nonsurgical observation of
PTMC in elderly
patients with low risk should be carefully selected . -
pubmed
Effect of
resveratrol on the progression of experimental
periodontitis in an ovariectomized
rat model of
osteoporosis : Morphometric , immune - enzymatic , and gene expression analysis . -
pubmed
OBJECTIVE : This study aimed to determine the role of
resveratrol (
RESV ) on the progression of experimental
periodontitis (
EP ) in ovariectomy
rats ( OVT ) . -
pubmed
Thus , this study aimed at investigating the effect of
RESV on the progression of
EP in
estrogen - deficient
rats . -
pubmed
Advanced head and neck cancer (
HNC ) can invade facial bone and cause
bone pain , thus posing a significant challenge to the quality of life of
patients presenting with advanced
HNC . -
pubmed
The present study was designed to investigate
HNC bone pain (
HNC - BP ) in an intratibial
mouse xenograft model that utilized an
HNC cell line (
SAS cells ) . -
pubmed
The in vivo efficacy of
galeterone as single drug alone and its ability in augmenting chemotherapy 's efficacy were also shown in
breast cancer xenograft
mouse model . -
pubmed
In this article , we present a case with
HaNDL syndrome in a 28 - year - old male
patient who presented with
confusion and
agitation after sudden onset of
headache ,
right hemiparesis , and
lymphocytosis pleocytosis . -
pubmed
Lesions of
mice under rotating shift schedules were larger and contained less prostabilizing fibrillar collagen and significantly increased areas of
necrosis . -
pubmed
Human papilloma virus genotype distribution in women with premalignant or
malignant lesions of the uterine cervix . -
pubmed
OBJECTIVE :
Cervical cancer is caused by
persistent infection with high - risk
human papillomavirus (
hrHPV ) . -
pubmed
This study evaluated the distribution of different types of
hrHPV relative to age in
cervical cancer and its precursor
lesions . -
pubmed
Among
HPV - positive women ,
HPV-16 ,
HPV-18 , and "
HPV other " types were found in 33.5 , 4.4 , and 49.4 % , respectively . -
pubmed
Among women with
cervical cancer , 75.8 % were infected with
HPV-16 or had
coinfection with
HPV-16 and "
HPV other " . -
pubmed
CONCLUSIONS :
HPV-16 is the most common type of
hrHPV in
HSIL +
lesions . -
pubmed
Therefore , women age > = 35 with persistent
infection with this type of
hrHPV need careful surveillance , as they are at high risk of progression to
cervical cancer . -
pubmed
Oncofetal protein accompanying irradiation - induced small - bowel
adenocarcinoma in the
rat . -
pubmed
A
tumor - associated protein was found in tissue derived from an X - irradiation - induced
adenocarcinoma in the small bowel of the
rat . -
pubmed
It shared common antigenic determinants both with a
rat fetal protein and a
perchloric acid - soluble protein isolated from the serum of the
tumor - bearing
rat . -
pubmed
[ Increased contents of
phenylethanolamine ,
m - octopamine and
p - octopamine in the hypothalamus and brain stem of spontanously
hypertensive rats ( S.H.R. -
pubmed
Phenylethanolamine ,
p - octopamine and
m - octopamine contents were determined in the hypothalamus and the brain stem of spontaneously
hypertensive Rats ( S.H.R. -
pubmed
Effects of the
diazafluoranthen derivative
AC-3579 (
NSC-170561 ) , a new experimental antitumour drug , on
rat hepatoma . -
pubmed
The effects of
AC-3579 (
NSC-170561 ) , a new experimental antitumour drug which depresses phospholipid catabolism in liver , were compared in
rat aflatoxin - induced
hepatoma and in non - neoplastic hepatocytes surrounding the
tumour . -
pubmed
Effect of
lithium upon
plaque and
gingivitis in the
beagle dog . -
pubmed
Animal models of
cardiac dysrhythmias . -
pubmed
After infusion of
51Cr -- labeled isologous platelets into one
patient with no
hematological disease and into four
patients with
thrombocytopenia , radioactivity was measured from 1 to 8 days . -
pubmed
Normal platelets survival was determined as 7 to 8 days in the first
patient , whereas the
thrombocytopenic patients showed a reduced survival , between 1 to 2 days . -
pubmed
The percentage of maximum recovery of transfused platelets was severely reduced in those
patients with
thrombocytopenia , ranging from 13 to 18 % , as compared with the normal 50 % found in the first
patient . -
pubmed
Such observations are used to implement the utility of serial biopsies from the beagle
dog prior to and during long - term study of potential
hepatic injury . -
pubmed
The authors recommend that any
infant having a
mid - line lumbar cutaneous abnormality , such as a
hemangioma ,
lipoma , hair patch or dimple , be evaluated to rule out tethering of the spinal cord . -
pubmed
Dependence and withdraw
syndromes related with
tobacco are mentioned . -
pubmed
All
endometriosis patients were treated medically with either
Danazol or
Buserelin . -
pubmed
The possibility of the
rabbit as a model for
HIV-1 infection is also discussed . -
pubmed
The C
cats shared fully with
BD cats a dramatic impairment in the visually delayed response . -
pubmed
This short - term
memory deficit was presumably due to a limited practice in visual learning in cage - reared
cats . -
pubmed
Coliforms were obtained from
36pc and streptococci from 18pc of swabs . -
pubmed
It is a known fact that pH in
rodent tumors decline significantly upon heating most likely due to breakdown of the
tumor blood circulation . -
pubmed
against
metrazol - induced
seizures was studied in
rats aged 7 , 12 , 18 and 90 days . -
pubmed
The results differed between the various age groups after longer intervals : The protection was longest in 18 - day - old
rats --
seizures did not appear even six hours after
VPA administration . -
pubmed
On the contrary , all 7 - day - old
rat pups exhibited
seizures two hours after
VPA . -
pubmed
In this study , urine - isolated microorganisms from
urinary tract infections were generally evaluated , and among these microorganisms , 407
E. - pubmed
coli
strains have been researched if they are uropathogenic
E. - pubmed
In nonfasted
obese rats ,
bromocriptine dramatically reduced both
cholesterol ( from 440 to 130 mg / dl ) and
triglyceride ( from 1570 to 540 mg / dl ) levels compared with controls . -
pubmed
Retained placenta in
cattle : the effect of treatment or nontreatment on
puerperal diseases and subsequent fertility . -
pubmed
In order to examine the effect of treated and untreated retained placenta ( RP ) on fertility and on the occurrence of puerperal and
fertility diseases , the records of 248
cows with
RP were examined : 199
cows were treated with intrauterine
tetracycline or systemic therapeutics , and 49 were left untreated . -
pubmed
The fertility of the
cows with
RP was lower than that of the controls . -
pubmed
The untreated
cows with
RP seemed to be treated more often for
endometritis and repeat breeding than either the treated animals or the controls . -
pubmed
As
patients with undetected volume contraction may be more endangered by
cardiovascular complications , the hematocrit should be monitored before and after dialysis , especially in
patients with high
weight gain and in
children . -
pubmed
The safety of
phenylpropanolamine in
patients with stable
hypertension . -
pubmed
A patient with
osteomyelitis of the distal right first metacarpal bone due to
Actinomyces israelii following a
punch injury during fisticuffs is described . -
pubmed
Analysis of the
pus in these
infections typically reveals
sulfur granules ; strict anaerobic conditions must be employed to culture the etiologic agent ,
A israelii . -
pubmed
Plasma concentrations of
TBPA were measured by rocket immunoelectrophoresis in 43 normal and 35
hypothyroid dogs . -
pubmed
Reference levels for
TBPA ranged between 205 and 474 mg / l.
Hypothyroid dogs had a mean
TBPA level of 315.0 mg / l ( SD : 91.1 mg / l ) . -
pubmed
Forty - five mostly elderly
patients with serious
infections were treated in a prospective , comparative and randomized pharmacokinetic study with
amikacin 11.0 or 15.0 mg / kg administered in a single daily dose as an intravenous , short - term infusion or with
amikacin 7.5 mg / kg administered twice daily in the same way . -
pubmed
[
Syndrome of lipid hyperperoxidation in
burn patients and its correction using autotransfusion of UV - irradiated blood ] . -
pubmed
Dynamics of lipid peroxidation was studied in blood serum of
patients with
burns of various severity and degree . -
pubmed
High efficiency of the procedure was demonstrated by reduction of the
lipid hyperperoxidation syndrome in
patients with
burns . -
pubmed
To assess the feasibility of percutaneous mitral commissurotomy , we undertook dilatation of
mitral stenosis in 26
adults . -
pubmed
The procedure was unsuccessful in six
patients (
hemopericardium in one , and five failures ) . -
pubmed
In a
patient with severe
valvular and subvalvular disease ,
mitral regurgitation increased from grade I to grade III . -
pubmed
Abnormalities of compliance and functional residual capacity were shown in eight young
children aged 2 - 8 years with
asthma during an acute attack . -
pubmed
In reviewing the literature that links
migraine with thromboembolic cerebral vascular events , a distinction is made between two
stroke events that occur in
migraine patients :
stroke associated with a
migraine attack ( a
migrainous stroke ) and
stroke unrelated to a
migraine attack ( a
non - migrainous stroke ) . -
pubmed
The two types of upper limb somatosensory evoked potential abnormality observed in nine
patients with
syringomyelia were reduced amplitude or absent cervical potentials and an abnormal central conduction time . -
pubmed
AZT was administered by intravenous drip infusion to 2 cases of
puerperal endometritis , 2 cases ( the same
patient ) of
vaginal wall abscess , 1 case of postoperative
lymphocele infection and 1 case of infected
ovarian cyst suspected , and it was effective for all of them . -
pubmed
Cranial hyperostosis of
squirrel monkeys (
Saimiri sciureus ) . -
pubmed
Development of broad spectrum of
tumors by
ethylnitrosourea in
mice and the modifying role of age , sex , and
strain . -
pubmed
[
Caries incidence in
children exposed to repeated topical applications of 8 per cent
tin fluoride ] . -
pubmed
Hyperkinetic episodes in Scottish Terrier
dogs . -
pubmed
The clinicopathological findings are reported in a
child with
congenital oculofacial diplegia ,
paresis of pharyngeal and laryngeal muscles , and concomitant
tetraparesis . -
pubmed
These findings are important clinically , particularly as they relate to
burn patients who often accumulate
iodine concentrations sufficient to depress immune responsiveness . -
pubmed
A review of the pathologic material from 34
patients having
bronchioloalveolar carcinoma has demonstrated two histopathologic types that have a bearing on the prognosis . -
pubmed
We applied the method to monitor ( by use of 24 - h urine specimens ) an uncomplicated , normally progressing pregnancy , a
patient with
metastatic melanoma being treated with cytostatic drugs , and ( in more detail ) the treatment of a
patient with high - grade
non - Hodgkin lymphoma . -
pubmed
Nuclear
estrogen binding sites in
human endometriosis . -
pubmed
Regional energy balance in
rat brain after transient
forebrain ischemia . -
pubmed
In eleven
patients with partial gastrectomy and isoperistaltic jejunal interpositions in
ulcer disease the concentrations of
bile acids and
lysolecithin were determined . -
pubmed
While with jejunal interpositions of 20 cm and more in length normal amounts of
duodenogastric reflux could be observed , in
patients with shorter segments the values were still pathological . -
pubmed
Auditory and vestibular function was monitored in 30
patients treated with
netilmicin for
urinary tract infection . -
pubmed
Results of highly sensitive vestibular tests in 15
patients including computerized analysis of the
nystagmus responses to caloric tests were compared with results obtained from a sample of normal
individuals . -
pubmed
Thirty
patients with
portal hypertension underwent as an emergency measure esophageal transection for uncontrolled
variceal bleeding . -
pubmed
Immediate operative
deaths , within one month , occurred in 17
patients . -
pubmed
Five
patients had a
recurrence of
varices . -
pubmed
Bleeding recurred in three
patients . -
pubmed
The
patients suffering from
left ventricular failure show
gastritis of varying intensity . -
pubmed
Microcirculatory disorders play an important role in the genesis of changes in the mucous membrane of the stomach in
patients with
heart failure . -
pubmed
Olfactory function was estimated in the group of 37
patients with the penetrating war
head injury . -
pubmed
In 4 ( 10.8 % )
patients mutual
anosmia was found . -
pubmed
The
patients with complicated
penetrating head injury were less successful at the level of all olfactive qualities comparing to those without
injury complications . -
pubmed
By contrast , 12- and 24 - month - old
animals experienced statistically significantly lesser high - energy rebound , developing greater
necrosis in the ischemic regions . -
pubmed
The purpose of this study was to examine the effects of
xenon and
nitrous oxide in equipotent doses of 0.3 MAC on
pain threshold and auditory response time in six healthy
male volunteers . -
pubmed
METHODS : High resolution magnetic resonance imaging ( MRI ) examinations of four
patients with primary
lymphoma of bone were reviewed retrospectively , and in each case intramedullary
tumors demonstrated " penetrating channels " extending through the cortex . -
pubmed
The MRI studies were correlated with the histopathologic assessment of the
tumor for each
patient . -
pubmed
Polymorphonuclear neutrophils ( PMN ) in freshly voided urines from 20 symptomatic
bacteriuric patients were examined . -
pubmed
PATIENTS : Two hundred
inpatients with steady , moderate or severe
pain within 72 hours after orthopedic surgery . -
pubmed
INTERVENTIONS :
Patients received a single oral dose of
bromfenac 25 , 50 , or 100 mg , or
ibuprofen 200 or 400 mg , when they experienced steady , moderate or severe
pain that , in their opinion , required an analgesic . -
pubmed
CONCLUSIONS : The relative potency of the analgesic effect of
bromfenac to
ibuprofen is 11 - 16.7 in
patients with
pain after orthopedic surgery . -
pubmed
[ Transthoracic and transesophageal follow - up in
patients with left
atrial thrombosis ] . -
pubmed
The
embolic risk and changes of
thrombus location and size were investigated in 29 consecutive
patients with echocardiographically proven
thrombi in the left atrium . -
pubmed
Thus , the
embolic rate was 14 % per
patient year . -
pubmed
All
patients received
phenprocoumon ( n = 4 ) or
aspirin at the time of
embolism . -
pubmed
Furthermore , in two
patients after cardiac thrombectomy left atrial
thrombi were seen again although patients were treated with anticoagulants . -
pubmed
On the other hand , in 12
patients ( 5 received oral anticoagulation , 2 received
aspirin )
thrombi completely resolved . -
pubmed
It can be concluded from these data , that the majority of
patients receiving anticoagulation profit from this therapy , however , a complete protection against
arterial embolism or reoccurrence of
thrombi can not be reached . -
pubmed
Left atrial spontaneous echo contrast was the only risk factor significantly associated with
thromboembolism in
patients with left
atrial thrombi . -
pubmed
The plasma level achieved by oral administration of 10 mg / kg
DV-7028 was more than 10(-7 ) M. The
hyperreactivity to
serotonin in isolated pulmonary artery segments from
MCT - treated
rats was significantly reduced by
DV-7028 ( 10(-7 ) M ) . -
pubmed
The present study suggests that
serotonin , released from platelets and accumulated in pulmonary capillaries , contributes to the initiation and/or progression of
pulmonary hypertension in
MCT - treated
rats . -
pubmed
[ Nutritional therapy in
cancer patients ] . -
pubmed
One partial ( 7 + months ) and two complete responses ( 36 and 26 + months ) were observed in 9
patients with
metastases from
cutaneous melanoma . -
pubmed
None of 6
patients with
metastases from
ocular melanoma responded . -
pubmed
Irradiated fetal thymus transplantation in a
patient with combined
immunodeficiency with predominant
T cell defect . -
pubmed
Male
reproductive toxicity study of
nitrazepam in
rats . -
pubmed
CASE : A 34 - year - old
woman was to undergo hysterectomy for
menorrhagia unresponsive to treatment . -
pubmed
CONCLUSION :
Vascular malformation have been found in various organs in
individuals with
hereditary hemorrhagic telangiectasia . -
pubmed
Although involvement of the uterus in
hereditary hemorrhagic telangiectasia is uncommon ,
telangiectasia should be considered in any
patient with
menorrhagia resistant to treatment . -
pubmed
After oral administration , the ED50s of
DFU - lactol in the carrageenan - induced paw
edema and lipopolysaccharide - induced
pyresis assays in
rats are comparable with the ED50s observed when dosing with
DFU . -
pubmed
Of 37
Staphylococcus epidermidis strains isolated between 1980 and 1981 , all were susceptible to
vancomycin and
teicoplanin on both MHA and BHIA . -
pubmed
Population analysis was performed with six
strains each of
Staphylococcus epidermidis and
Staphylococcus haemolyticus ( three with
vancomycin MIC & gt ; or = 8 micrograms / ml and three with
vancomycin MIC & lt ; or = 4 micrograms / ml using BHIA ) . -
pubmed
The population curves of the
Staphylococcus epidermidis strains showed a homogeneous pattern of susceptibility . -
pubmed
Whereas , those for two
Staphylococcus haemolyticus strains (
vancomycin MIC = 8 micrograms / ml using BHIA ) showed a typical heterogeneous pattern . -
pubmed
In heifers in which
mastitis was associated with increased rectal temperature or other systemic signs , the proportion of clinically affected quarters that were infected with
Staph . - pubmed
In
children with
MPGN and
nephrotic syndrome and/or
impaired renal function , a trial of
steroids is warranted ( grade A ) . -
pubmed
In
adults with
MPGN ,
impaired renal function , and/or
nephrotic - range
proteinuria , a trial of
aspirin ( 325 mg daily ) ,
dipyridamole ( 75 to 100 mg tid ) , or a combination of the two for 12 months is reasonable ( grade B ) . -
pubmed
A 55 years - old
woman was admitted to the hospital because fifteen days of
malaise ,
right upper quadrant pain and
fever . -
pubmed
Acute effects of thirty minutes of light - intensity , intermittent exercise on
patients with
chronic fatigue syndrome . -
pubmed
BACKGROUND AND PURPOSE : Currently , there is no consensus on exercise prescription for
patients with
chronic fatigue syndrome (
CFS ) . -
pubmed
This investigation examined whether light - intensity , intermittent physical activity exacerbated symptoms in
patients with
CFS immediately following exercise to 7 days following exercise . -
pubmed
After in vitro characterization of each virus ,
human prostate cancer cells infected with these viruses were subcutaneously injected into athymic
mouse . -
pubmed
Right GPi lesions were not consistently associated with
neuropsychological deficit , except in one study that included a significant proportion of demented
patients . -
pubmed
The proportion of
pertussis infections resulting in recognizable symptoms may have increased among vaccinated persons because of a mismatch of the vaccine
strain and circulating
Bordetella pertussis strains . -
pubmed
Ovariectomized
cynomolgus monkeys have previously been investigated as a
nonhuman primate model of
postmenopausal osteoporosis ( Jerome et al . -
pubmed
In the present study , Fourier transform infrared microspectroscopy ( FTIRM ) was used to verify that differences in bone mineral quality and quantity in the vertebrae of mature intact ( INT ) and ovariectomized ( ovx )
monkeys were analogous to those seen in
osteoporotic and nondiseased
human bones . -
pubmed
These spectra were compared with those of both trabecular and previously reported osteonal bone obtained from 3 " normal " and 11 postmenopausal
osteoporotic human subjects . -
pubmed
While variations in the mineral : matrix ratio ( mineral content ) ,
carbonate :
phosphate ratio , and crystallinity are typical for trabecular bone from iliac crests of normal
human subjects , the values of these parameters were relatively static for trabecular bone from postmenopausal
osteoporotic human subjects . -
pubmed
In general , trabecular bone from postmenopausal
osteoporotic human subjects exhibited decreased mineral content ( 1.0 + /- 0.5 vs. 2.9 + /- 0.6 ) , increased crystallinity , and increased
carbonate :
phosphate relative to controls . -
pubmed
These data support the hypothesis that ovariectomized adult
monkeys are an excellent model for
postmenopausal osteoporosis , and can be used for the evaluation of therapeutic modalities . -
pubmed
Microsphaeropsis olivacea keratitis and consecutive
endophthalmitis . -
pubmed
PURPOSE : To report a case of
fungal keratitis with consecutive
endophthalmitis caused by
Microsphaeropsis olivacea . -
pubmed
RESULTS : A 51 - year - old
man developed
fungal keratitis and consecutive
endophthalmitis after sustaining a
penetrating injury to the right eye . -
pubmed
The ability of
Staphylococcus aureus to invade mammalian cells may explain its capacity to colonize mucosa and to persist in tissues after
bacteraemia . -
pubmed
OBJECTIVE : To evaluate the efficacy of inhaled
albuterol for treatment of
hyperkalemia in premature
neonates by conducting a prospective , randomized placebo - controlled and double - blinded clinical trial . -
pubmed
Brain circuits involved in emotional learning in antisocial behavior and
social phobia in
humans . -
pubmed
METHODS : Six
patients ranging in age from 6 to 37 years with traumatic high - flow
priapism underwent superselective embolization with
gelatin sponges ( n=3 ) or minicoils ( n=3 ) . -
pubmed
In 2
patients , repeated embolization led to a flow reduction in the
fistula , which spontaneously occluded a few days later . -
pubmed
CONCLUSIONS : Transarterial superselective embolization is an effective and well - tolerated therapy in
patients with traumatic
priapism . -
pubmed
BACKGROUND : The aim of this study was to identify the independent histopathologic prognostic factors for
patients with
cervical carcinoma treated with radical hysterectomy including paraaortic lymphadenectomy . -
pubmed
METHODS : A total of 187
patients with stage IB to IIB
cervical carcinomas treated with radical hysterectomy and systematic retroperitoneal lymphadenectomy were retrospectively analyzed . -
pubmed
RESULTS : Using multivariate Cox regression analysis , lymph node ( LN ) status ( negative vs.
metastasis to pelvic nodes except for common iliac nodes vs. common iliac / paraaortic node
metastasis ) , histopathologic parametrial invasion , lymph - vascular space invasion ( LVSI ) , and histology of pure
adenocarcinoma were found to be independently related to
patients ' poor survival . -
pubmed
For
patients who had a
tumor histologically confined to the uterus and have neither parametrial invasion nor lymph node
metastasis , LVSI was the most important prognostic factor , and histologic type , depth of cervical stromal invasion , and
tumor size were not related to survival . -
pubmed
The survival of
patients with a
tumor extending to parametrium or pelvic lymph node(s ) was adversely affected by histology of pure
adenocarcinoma . -
pubmed
When the
tumor extended to common iliac or paraaortic nodes ,
patients ' survival became quite poor irrespective of
LVSI or histologic type of pure
adenocarcinoma . -
pubmed
Patients ' prognosis could be stratified into low risk ( patients with a
tumor confined to the uterus not associated with
LVSI : n = 80 ) , intermediate risk ( patients with a
tumor confined to the uterus associated with positive LVSI , and patients with squamous / adenosquamous
carcinoma associated with pelvic lymph node
metastasis or parametrial invasion : n = 86 ) , and high risk ( patients with pure
adenocarcinoma associated with pelvic lymph node
metastasis or parametrial invasion , and
patients with common iliac / paraaortic node
metastasis : n = 21 ) with an estimated 5 - year survival rate of 100 + /- 0 ( mean + /- SE)% , 85.5 + /- 3.9 % , and 25.1 + /- 9.7 % , respectively . -
pubmed
Prognosis for
patients with cervical
carcinoma may be stratified by combined analysis of these histopathologic prognostic factors . -
pubmed
CONCLUSIONS : Three hundred eighty - one
patients reported that they were receiving antidepressant therapy for
psychiatric and other medical reasons . -
pubmed
CLINICAL IMPLICATIONS :
Patients receiving antidepressant therapy are at risk of developing
xerostomia and
orthostatic hypotension , as well as experiencing the adverse effects of interaction with vasoconstrictors . -
pubmed
In 1998 we conducted a multicentre study in Spain on the susceptibility of
Streptococcus pyogenes isolates to different
14 - , 15 - and 16 - membered macrolides and
clindamycin , in which the number of
strains examined was proportional to the number of inhabitants in each geographical area . -
pubmed
Surgical correction of
cor triatriatum dexter in a
dog under extracorporeal circulation . -
pubmed
A shiba inu
dog with marked
abdominal distension was diagnosed with
cor triatriatum dexter and surgical correction was performed under extracorporeal circulation . -
pubmed
Although several methods have been used to treat
cor triatriatum dexter in
dogs , the authors consider surgical correction under extracorporeal circulation to be a reliable approach . -
pubmed
Metabolic studies of a
patient with
osteoporosis and
diabetes mellitus . -
pubmed
The demonstration that initiation of cardiovascular protective medications , including lipid - lowering therapy , prior to hospital discharge for
atherosclerotic cardiovascular events results in a marked increase in treatment rates , improved long - term
patient compliance , and better clinical outcomes has led to the revision of national guidelines to endorse this approach as the standard of care . -
pubmed
Recent studies suggest that when the beta - blocker
carvedilol is initiated in acute -
MI patients with
left ventricular dysfunction with or without symptoms of
heart failure prior to hospital discharge , it is safe and effective and improves clinical outcomes . -
pubmed
OBJECTIVE : Resistance to
imatinib mesylate monotherapy is clearly a barrier to successful treatment of
chronic myeloid leukemia (
CML )
patients . -
pubmed
METHODS : A total of 225
infants ( mean age 30 days ) were diagnosed with uncomplicated
VSD : 31 ( 14 % ) subpulmonary VSD , 159 ( 70 % ) perimembranous , and 35 ( 16 % ) muscular . -
pubmed
The
patients were divided into two groups according to the presence or absence of
congestive heart failure (
CHF ) . -
pubmed
SC occurred in 107
patients ( 48 % ) ; three ( 10 % ) of 31 with
subpulmonary VSD , 75 ( 47 % ) of 159 with
perimembranous VSD , and 29 ( 83 % ) of 35 with a
muscular VSD . -
pubmed
In three
SC patients with a subpulmonary VSD , there was no
aortic valve prolapse and no
aortic regurgitation . -
pubmed
SC occurred in 96 % of
SC patients with a
perimembranous VSD by the age of 6 years , and in 93 % of those with a
muscular VSD by the age of 3 years . -
pubmed
In
patients without
CHF , the rate of
SC was 72 % ; 23 % in
subpulmonary VSD , 74 % in perimembranous , and 85 % in muscular . -
pubmed
The best TcpO(2 ) parameters to predict the efficacy of spinal cord stimulation to improve limb salvage in
patients with inoperable critical leg
ischemia . -
pubmed
METHODS : Studies in which inoperable
CLI patients were treated with conservative treatment with or without SCS , and in whom various
TcpO ( 2 ) measurements were performed before and during treatment were pooled to investigate which
TcpO ( 2 ) parameter(s ) were best to detect
patients who benefit most from SCS treatment as to limb salvage . -
pubmed
Selection using ( a combination of )
TcpO ( 2 ) measurements substantially improves limb salvage of
patients treated with SCS for inoperable
CLI . -
pubmed
Here we demonstrate 2
patients who showed marked
hyperglycemia after
androgen - deprivation therapy for
prostate cancer and the efficacy of the
thiazolidinedione pioglitazone on their glycemic control . -
pubmed
Case 1 was a 61 - year - old
man diagnosed with
prostate cancer who had
type 2 diabetes mellitus for 7 years . -
pubmed
Six months after starting the
leuprolide treatment , the
patient complained of thirst and
weight loss and was diagnosed with
diabetes mellitus with a fasting
glucose of 19.4 mmol / L and HbA1c of 9.9 % . -
pubmed
Insulin resistance after the
androgen - deprivation therapy might lead to marked
hyperglycemia in these
patients . -
pubmed
To explore whether the procoagulant activity of vessel wall - bound cells regulates
thrombus expansion , we studied in vitro spatial clot growth initiated by cultured
human cells of different types in contact pathway - inhibited , non - flowing
human plasma . -
pubmed
CONCLUSIONS : If health care personnel are exposed to
hepatitis A and
B virus , the combined vaccination should be preferred to the concomitant one , as this vaccination scheme induced earlier seroprotection against
hepatitis B virus infection ( & gt ; or = 10 IU / l and & gt ; or = 100 IU / l ) . -
pubmed
A comparison of continuous renal replacement therapy to intermittent dialysis in the management of
renal insufficiency in the acutely III surgical
patient . -
pubmed
Acute renal failure (
ARF ) occurs in 10 per cent to 23 per cent of intensive care unit
patients with mortality ranging from 50 per cent to 90 per cent . -
pubmed
We hypothesize that renal function and hemodynamic stability in
trauma/ surgical critical care
patients are better preserved by CRRT than by ID . -
pubmed
We performed a retrospective review of
trauma / surgical critical care
patients requiring renal supportive therapy . -
pubmed
CRRT provides better control of
azotemia while preserving hemodynamic stability in
patients undergoing renal replacement therapy . -
pubmed
Data were 4518 observations of somatic cell score ( SCS ) and
bacterial infection from both udder halves of 310
goats from 5 herds in Northern Italy . -
pubmed
Patients with advanced , incurable
non - small cell lung cancer (
NSCLC ) may derive a clinical benefit from first- and second - line chemotherapy , but third - line treatment with available cytotoxic agents is not effective . -
pubmed
Erlotinib is the first of this novel class of drug to demonstrate a statistically significant and clinically relevant difference in overall survival , progression free survival and time to disease related symptoms (
cough ,
pain ,
shortness of breath ) compared with treatment with best supportive care in
patients who have failed standard first- or second - line chemotherapy . -
pubmed
OBJECTIVE :
Patients with metastatic
breast cancer (
MBC ) generally have a poor prognosis . -
pubmed
PATIENTS AND METHODS : From September 2000 to September 2001 , informed consent was obtained from 20 heavily pretreated
women with
MBC . -
pubmed
One
patient had grade III
neutropenia , which was reversible on cessation of treatment . -
pubmed
The goal of this study was to verify the prevalence of
anxiety and
depression in
adolescents , and their relationship with
signs and symptoms of
TMD . -
pubmed
This is a five - year retrospective study of 32 histologically diagnosed cases of
Kaposi ' s sarcoma (
KS ) who had undergone
HIV antibody testing at the Jos University Teaching Hospital : 13 cases ( 40 % ) were
HIV - negative . -
pubmed
This pattern of
KS seen in Nigerian patients shows similarities with other African countries which have been affected by the
HIV epidemic . -
pubmed
PARTICIPANTS : Eighteen
subjects with recurrent
ankle inversion sprain . -
pubmed
Early experience with venous stenting suggests that it may be a helpful treatment for
patients with
PTS but more experience and longer follow - up is required to define the subgroups of
patients for whom it is most appropriate . -
pubmed
CLINICAL PICTURE : A previously well 12 - year - old
boy presented with
fever , right - sided flank
pain and
weight loss of 1 - month duration . -
pubmed
Patients with maximum RIFLE class R , class I and class F had hospital mortality rates of 8.8 % , 11.4 % and 26.3 % , respectively , compared with 5.5 % for patients without
acute kidney injury . -
pubmed
Adherence to maintenance therapy is often poor in
patients with
asthma . -
pubmed
In this 12 - week , randomized , double - blind , double - dummy , parallel - group study , 617
patients with mild to moderate persistent
asthma ( mean forced expiratory volume in 1s [ FEV1 ] 78.5 % predicted ) who were not optimally controlled on inhaled
corticosteroids ( 200 - 500 microg / day ) were randomized to once - daily
budesonide /
formoterol ( 80/4.5 microg , 2 inhalations in the evening ) , twice - daily
budesonide /
formoterol ( 80/4.5 microg , 1 inhalation ) , or a corresponding dose of
budesonide once - daily ( 200 microg , 1 inhalation in the evening ) . -
pubmed
Budesonide /
formoterol administered once daily in the evening is a convenient treatment regimen that is as effective in improving
asthma control as twice - daily dosing in
patients with mild to moderate persistent
asthma . -
pubmed
OBJECTIVE : The aim of the present study was to uncover proteins differentially expressed in the WAT of
overweight /
obese subjects and study the role of the identified proteins in adipocyte differentiation . -
pubmed
RESULTS :
Human visceral adipose tissue of
overweight /
obese subjects displayed a differential protein expression profile , compared with that of normal - weight controls . -
pubmed
Although potentially autoreactive T cells are present even in healthy subjects , most
individuals do not develop
autoimmune disease . -
pubmed
Despite the available effective therapy the majority of
individuals with
obstructive sleep apnea and
cardiovascular disease remains underdiagnosed and untreated . -
pubmed
We investigated such effect in Taiwanese
type 2 diabetic patients . -
pubmed
MATERIALS AND METHODS : This prospective study has been carried out on 33
patients ( 23
males and 10 females ) with
lower ureteral stone ( 17 cases in the right ureter and 16 in the left ) located under iscial spine as was indicated in their KUB . -
pubmed
All
patients underwent ureteroscopy , and accordingly those with submucosal
ureteral stones were distinguished . -
pubmed
The average distance between the peak of stone and the middle line of sacrum in
patients with
submucosal ureteral stone was 9.7 mm with an accuracy of 1.4 mm , a confidence interval 95 % and standard deviation of 3.1 mm . -
pubmed
The contact lens wearer ( CLW ) group consisted of 22 eyes of 22
patients ( age distribution , 23 - 50 years ) with a history of
refractive errors and more than ten - year soft contact lens wear . -
pubmed
Thirty - eight eyes of 38
patients ( age distribution , 18 - 52 years ) with
refractive errors but no history of contact lens wear were observed as the controls . -
pubmed
Effects of antiepileptic drug therapy on
vitamin D status and biochemical markers of bone turnover in
children with
epilepsy . -
pubmed
Reports of decreased serum
25 - hydroxyvitamin D (
25 - OHD ) and
altered bone metabolism associated with antiepileptic drug ( AED ) treatment are inconsistent and predominantly restricted to
adults . -
pubmed
In this cross - sectional observational study , the aim was to evaluate the influence of AED treatment on
vitamin D status and markers of bone turnover in
children with
epilepsy . -
pubmed
Atherosclerosis is accelerated in diabetic
patients . -
pubmed
These results establish the
canine as a model for future studies of
TDA . -
pubmed
Changes in natriuretic peptides following passive containment surgery in
heart failure patients with
dilated cardiomyopathy . -
pubmed
To evaluate the influence on circulating plasma levels of natriuretic peptides following passive containment surgery in
heart failure patients with
dilated cardiomyopathy , thirteen
patients with
dilated cardiomyopathy subjected to cardiac surgery received the Acorn Cardiac Support Device . -
pubmed
Patients with
ischemic cardiomyopathy ( n=7 ) underwent coronary artery bypass surgery receiving 2 - 3 bypass grafts . -
pubmed
In the
idiopathic cardiomyopathy group ( n=6 ) , mitral valve plasty was performed in five
patients while one
patients received the Cardiac Support Device only . -
pubmed
Evaluation of drug - metabolizing and functional competence of
human hepatocytes incubated under
hypothermia in different media for clinical infusion . -
pubmed
Hepatocyte transplantation has been proposed as a method to support
patients with
liver insufficiency . -
pubmed
CASE PRESENTATION : A 23 - year - old
man presented to us with right
hip pain of more than 10 years duration . -
pubmed
In the MRAUP group , 87 % of the
patients ( 26
patients ) had a final VAS for
snoring below 3 , while in the RAUP group 63 % of the
patients ( 19
patients ) were below 3 on the scale ( P & lt ; 0.05 ) . -
pubmed
These
mice , engineered with a common genetic profile to
human melanoma , provide a system to study
melanoma 's cardinal feature of
metastasis and for preclinical evaluation of agents designed to prevent or treat
metastatic disease . -
pubmed
Cannabis consumers should be made aware of their
tobacco use while consuming cannabis and the risk of inducing
nicotine addiction through cannabis use , despite the perceived disconnect between the two substances . -
pubmed
Nitrofurantoin and
Nalidixic acid can be considered as the first line antibiotics for prophylaxis and or treatment of
patients with recurrent
UTI , while
Meropenam and
Ciprofloxacin can be used empirically in treating
patients with complicated
UTI . -
pubmed
Construction of flocculating
yeast strains by genetic approach and utilization of
yeast flocculation for
ethanol production from various feedstocks were presented . -
pubmed
[ Dorsal release of the ankle with transfer of the posterior tibial tendon in
patients with
paralytic drop foot ] . -
pubmed
RESULTS : Six
patients ( mean age 52 years ) presented with a neurologic fixed drop
foot deformity that had developed more than 8.3 years ago . -
pubmed
licheniformis NH1
strain was achieved in the presence of 7.5 g / l
chicken feathers and 1 g / l
yeast extract . -
pubmed
High levels of
15 - oxygenated steroids in circulation of
patients with
multiple sclerosis : fact or fiction ? -
pubmed
The levels were reported to be increased in
patients with
multiple sclerosis in a progressive phase and the authors suggested that this could be utilized diagnostically . -
pubmed
Using combined gas chromatography - mass spectrometry we fail to detect significant plasma levels of
15HC either in healthy controls or in
patients with
multiple sclerosis ( levels & lt ; 2 ng / ml ) . -
pubmed
Recently , a critical role of iNKT cells in the
mouse model of
asthma and also in
asthma patients has been reported , while some contradictory results have also been described . -
pubmed
Here , we summarize the experimental results in
mouse and
human systems , and discuss the current understanding of the role of NKT cells in the pathogenesis of
asthma , including a possible mechanism by which iNKT cells are activated in
asthma patients . -
pubmed
We evaluated and compared the in vivo tissue distribution and imaging properties of
64Cu - X -( Gly - Ser - Gly )- KCCYSL peptide ( X =
1,4,7,10 , tetraazacyclododecane - N , N ' , N '' , N '''- tetracetic acid ,
[ DOTA ] 1,4,8,11 - tetraazabicyclo [ 6.6.2 ] hexadecane-4,11 - diacetic acid [ CB - TE2A ] , and
1,4,7 - triazacyclononane-1,4,7 - triacetic acid [
NOTA ] chelators ) in a
human breast cancer xenograft
mouse model using dual modality PET and computed tomography ( CT ) . -
pubmed
The synthesized peptides
DO3A - GSG - KCCYSL , CB - TE2A - GSG - KCCYSL , and NO2A - GSG - KCCYSL were purified , radiolabeled with
64Cu , and evaluated for
human breast cancer cell (
MDA - MB-435 ) binding , 50 % inhibitory concentration , and serum stability . -
pubmed
Cutaneous hyalohyphomycosis caused by
Paecilomyces lilacinus successfully treated by oral
voriconazole and
nystatin packing . -
pubmed
We describe a
woman with
liver cirrhosis with
hemorrhagic , bullous ,
ulcerative leg lesions caused by
Paecilomyces lilacinus . -
pubmed
Human papillomavirus (
HPV ) can infect oral mucosa , causing asymptomatic
infection or
warty lesions . -
pubmed
Several case - control studies have confirmed
HPV as an independent risk factor for
squamous cell carcinoma . -
pubmed
HPV - related cancers seem to have better prognoses and different risk factors than do
HPV - negative ones . -
pubmed
The increased risk of
HPV infection in
HIV patients has been associated with impaired immune response to
HPV , highly active antiretroviral therapy , aging of the
HIV - infected patients , and direct interaction between the 2 viruses . -
pubmed
HPV32 seems to be much more prevalent in asymptomatic
HPV infections and
warts among those infected with
HIV than among those in the general population . -
pubmed
METHODS : Twenty - five healthy
women of reproductive age with no ocular pathology or
systemic diseases were recruited . -
pubmed
METHODS AND RESULTS : The study material consisted of a total of 219
patients : 31 with usual
ductal hyperplasia (
UDH ) , 25 with
atypical ductal hyperplasia (
ADH ) , 30 with
ductal carcinoma in situ (
DCIS ) and 133 with invasive
carcinoma . -
pubmed
This isolate was further identified by partial 16S rDNA sequencing and phylogenetic analysis revealed that the
strain belonged to Gammaproteobacteria and was closely related to
Halomonas bolviensis ( 96 % sequence similarity , 570 bp ) . -
pubmed
In cell culture experiments , top - type hydrogels demonstrated excessive suppression of
human epidermal
carcinoma A431 cell proliferation over 5 days due to the initial high concentration of released
PTX . -
pubmed
As an extended work , we sought to confirm its efficacy and safety of
Ginsenoside - Rd in
patients with
acute ischaemic stroke . -
pubmed
METHODS : We conducted a randomized , double - blind , placebo - controlled trial involving 390
patients with acute
ischaemic stroke in a 3:1 ratio to receive a 14 - day intravenous infusion of
Ginsenoside - Rd or placebo within 72 h after the onset of
stroke . -
pubmed
Physiological response of
mouse retinal
ganglion cells to electrical stimulation : effect of
soma size . -
pubmed
An epiretinal prosthesis aims to restore functional vision by stimulating electrically the retinal
ganglion cells ( RGCs ) in
patients affected by
photoreceptor degenerative diseases , such as age - related
macular degeneration (
AMD ) and
retinitis pigmentosa (
RP ) . -
pubmed
Genetic diagnosis and cochlear implantation for
patients with
nonsyndromic hearing loss and
enlarged vestibular aqueduct . -
pubmed
OBJECTIVE : To review the genotype and cochlear implantation outcome of
patients with
nonsyndromic hearing loss and
enlarged vestibular aqueduct . -
pubmed
METHODS : Twenty - one Chinese
children with
nonsyndromic hearing loss and
enlarged vestibular aqueduct underwent genetic examination . -
pubmed
Cochlear implantation is a safe and effective treatment in
patients with
enlarged vestibular aqueduct . -
pubmed
Late - onset
patients with
sporadic amyotrophic lateral sclerosis in Japan have a higher progression rate of ALSFRS - R at the time of diagnosis . -
pubmed
This study sought to investigate the clinical features of
patients with late - onset
ALS compared with those with early - onset
ALS using the progression rate ( DeltaFS ) . -
pubmed
METHODS : Forty - five
patients with
sporadic ALS were divided into 2 groups : 23
patients with early - onset of
ALS ( < 65 years ; early onset ) and 22
patients with late - onset
ALS ( > = 65 years ; late onset ) . -
pubmed
Every
patient was followed up from the time of initial diagnosis to the primary endpoint (
death or time culminating in
death without tracheostomy or ventilation assistance including noninvasive positive pressure ventilation ) or for at least 48 months after initial diagnosis . -
pubmed
CONCLUSION : Our finding suggested that
patients with late - onset
ALS showed more rapid
disease progression than those with early - onset
ALS using DeltaFS . -
pubmed
Here we identify cold
shock as a novel trigger of SG assembly in
yeast and
mammals . -
pubmed
BACKGROUND / AIMS : The immunosuppressive drug
tacrolimus (
FK506 ) is used clinically to reduce the rejection rate in
patients with kidney transplantation ; however , the resultant
nephrotoxicity remains a serious problem . -
pubmed
Acoustic radiation force impulse ( ARFI ) imaging with Virtual Touch Tissue Quantification in
liver disease associated with
cystic fibrosis in
children . -
pubmed
MATERIALS AND METHODS : Virtual Touch Tissue Quantification , an implementation of US ARFI with shear - wave velocity ( SWV ) measurements was used in 75
children with
cystic fibrosis (
CF ) and suspected
CFLD to quantify hepatic stiffness . -
pubmed
RESULTS : Among
CF patients , median SWV was significantly higher in patients with clinical , biochemical and US signs of
hepatic involvement than in
patients without US evidence of
liver disease 1.08 m / s [ ( 95 % confidence interval ( CI ) , 1.02 - 1.14 ] . -
pubmed
CONCLUSIONS : ARFI is an innovative screening technique able to help identify
CFLD in
children . -
pubmed
To investigate this mechanism , we examined the levels of intracellular reactive
oxygen species ( ROS ) and
neurotoxicity in
rat primary neurons using E22P - Abeta42 , a mutant that induces a turn at positions 22 and 23 , and E22V - Abeta42 , a turn - preventing mutant . -
pubmed
Role of gastric bypass in
patients with unresectable advanced
carcinoma of stomach . -
pubmed
Adipose - specific gene deletion in
mice is crucial in determining gene function in adipocyte homeostasis and the development of
obesity . -
pubmed
PATIENTS AND METHODS : We patch tested 480 consecutive
patients , visited at the Mekele IDC , exhibiting symptoms of
contact dermatitis . -
pubmed
In in vitro screening experiments ,
MIL showed strong antiproliferation activity in several
human cancer cell lines , especially in
HepG2 cells with an IC50 of 1.51 microM. -
pubmed
In
HepG2 tumor - bearing
mice models ,
MIL remarkably and dose dependently inhibited
tumor growth . -
pubmed
We present the case of a
patient who presents a harmonic
vestibular deficit of the right ear . -
pubmed
In this case we detail the importance of taking
hematological disorders into consideration in the differential diagnosis of
patients with
otoneurological symptoms , and we also review the etiopathogenic mechanisms , symptoms , diagnosis , and therapeutic options for
chronic myeloid leukemia with
sudden hearing loss and
vertigo . -
pubmed
MATERIAL AND METHODS : Surgical outcome of 36
patients with large cystic
VS was retrospectively assessed , and compared with a group of 67
patients with large solid
VS . -
pubmed
At 1 year after surgery , 75.8 % of the
patients with cystic
VSs had favorable facial nerve function and 24.2 % had poor function . -
pubmed
CONCLUSION : In most cystic
VS patients , favorable facial nerve function can be attained by surgical treatment via retrosigmoid approach . -
pubmed
Clinically diagnosed
patients with
PT ( n = 44 ) and
ET ( n = 22 ) with
rest tremor were included . -
pubmed
Rest
tremor suppression was found in 39/44
PD patients and in 2/22
patients with
ET during the personal assessment . -
pubmed
MATERIAL AND METHOD : This was a retrospective study of 85
patients with
nasal polyposis who were treated by endoscopic
sinus surgery between the years of 2005 and 2010 . -
pubmed
RESULTS : When the
patients with ( 16.4 % ) and without ( 83.6 % )
bronchial asthma were compared regarding the eosinophil , lymphocyte , neutrophil , macrophage , mast cells and goblet cells/ epithelial cell rate , no statistical significance was found ( p & gt ; 0.05 ) . -
pubmed
The neutrophil amount ( 16.53 + - 19.87 ) on the preparations of the
patients with
metaplasia was higher than the neutrophil amount ( 8.71 + - 23.98 ) on the preparations of the
patients without
metaplasia ( p=0.001 ) . -
pubmed
Attenuated effects of
Neu2000 on
hypoxia - induced synaptic activities in a
rat hippocampus . -
pubmed
Patella dislocation is a common
injury in children and
adolescents and occurs at a rate of 29 to 43 per 100,000 among the 10- to 17 - year - olds . -
pubmed
Effects of body - color mutations on vitality : an attempt to establish easy - to - breed see - through
medaka strains by outcrossing . " -
pubmed
See - through "
strains of
medaka are unique tools for experiments : their skin is transparent , and their internal organs can be externally monitored throughout life . -
pubmed
The patient was an 18 - year - old
man who had undergone surgical closure of
ventricular septal defect at the age of 2 years . -
pubmed
In regenerative medicine and drug screening for the treatment of severe
liver diseases ,
human induced pluripotent stem ( iPS ) cell - derived mature functional hepatocytes are considered to be a potentially good cell source . -
pubmed
When these cells were cultured in a suitable extracellular matrix gel , they eventually formed a cholangiocytic
cyst - like structure with epithelial polarity , suggesting that
human iPS cell - derived hepatic progenitor - like cells have a bipotent differentiation ability . -
pubmed
Approximately 50 % of the world 's population is infected with
Helicobacter pylori , leading to
chronic inflammation , which increases the risk for
gastric adenocarcinoma . -
pubmed
Infection of
MyD88 - deficient ( Myd88 (-/- ) ) mice with Helicobacter resulted in early and rapid advancement to
gastric dysplasia as early as 25 weeks postinfection . -
pubmed
METHODS : Using a Social Observation Inventory , 10
patients with
bvFTD and 10
patients with
Alzheimer ' s disease (
AD ) were compared to their caregiver interlocutors on 1 - hour mealtime , in - home videotaped segments . -
pubmed
BACKGROUND :
Anomia is a common and debilitating symptom for many
dementia sufferers , but is particularly marked in patients with the semantic variant of
primary progressive aphasia ,
semantic dementia (
SD ) . -
pubmed
Our results reveal the high thermal and
light sensitivities of
C. - pubmed
BACKGROUND : It is largely accepted that specific immunological parameters in
solid malignancies are associated with
patient 's prognosis . -
pubmed
So far there are no studies analyzing the macrophage polarization in cervical lymph nodes of
oscc patients . -
pubmed
In the present study we aimed to correlate macrophage polarization in different anatomical lymph node compartments of
patients diagnosed with oscc with histopathologic parameters of the primary
tumor ( T- , N- , L- , V- , Pn - status , grading ) . -
pubmed
Our aim was to expose
rats to one month of training ( 70 or 700 g load ) on a custom - designed weight - lifting apparatus for analysis of reactive forces and muscle morphology prior to
muscle hypertrophy . -
pubmed
METHODS : Twenty - three
patients ( 17
men and 6
women , range : 45 - 85 years old , mean age 65 years ) with malignant
liver tumors underwent ultrasound - guided percutaneous
tumor ablation [ radiofrequency ( n = 14 ) , microwave ( n = 9 ) ] followed by intravenous contrast - enhanced CBCT . -
pubmed
Local
tumor recurrence and new
liver tumors were found 3 mo after initial treatment in one
patient ( 4 % ) . -
pubmed
The fusion of baseline MDCT and peri - procedural CBCT images was feasible in all
patients and showed satisfactory
tumor coverage ( at least 5 - mm margin ) . -
pubmed
Further , control groups may be contaminated by significant numbers of preclinical
AD patients , which also reduces the power of genetic association studies . -
pubmed
More Extensive Pelvic Lymph Node Dissection Improves Survival in
Patients with Node - positive
Prostate Cancer . -
pubmed
aureus
ATCC 29213 as the reference and quality control
strain . -
pubmed
A 58 - year - old
man was on dialysis for
type II diabetes and
chronic renal failure . -
pubmed
Occurrence of antibodies to
Anaplasma phagocytophilum in patients with suspected
tick - borne encephalitis . -
pubmed
INTRODUCTION AND OBJECTIVES :
Human granulocytic anaplasmosis (
HGA ) is an emerging
tick - borne infectious disease caused by
Anaplasma phagocytophilum . -
pubmed
phagocytophilum in blood sera of
humans with suspected
tick - borne encephalitis . -
pubmed
In a separate analysis of all 48
patients initially identified , the MRIs of
patients with ( n = 26 ) and without ( n = 22 )
FBDS were compared by 2 neuroradiologists blinded to the clinical details . -
pubmed
The
patients often presented with
renal mass . -
pubmed
Variation in
relapse frequency and the transmission potential of
Plasmodium vivax malaria . -
pubmed
Unexpected arterial wall and cellular
inflammation in
patients with
rheumatoid arthritis in remission using biological therapy : a cross - sectional study . -
pubmed
BACKGROUND : Increasing numbers of
patients ( up to 40 % ) with
rheumatoid arthritis (
RA ) achieve remission , yet it remains to be elucidated whether this also normalizes their cardiovascular risk . -
pubmed
RESULTS : Overall , arterial wall
inflammation was comparable in
RA patients ( n = 23 ) in long - term remission and controls ( n = 17 ) . -
pubmed
METHODS : In a prospective study , 41
FECD patients who received DSAEK were compared to 40
cataract patients with normal corneas who received
cataract surgery ( control group ) . -
pubmed
Catquest-9SF effect size was 1.32 ( CI : 1.0 - 1.6 ) in the control group , 1.84 ( CI : 1.4 - 2.3 ) in
FECD patients who received phacoemulsification and intra - ocular lens implantation in combination with DSAEK ( n = 26 ) and 1.37 ( CI : 0.6 - 2.1 ) in pseudophakic
FECD patients who received DSAEK ( n = 15 ) . -
pubmed
CONCLUSIONS : DSAEK surgery leads to considerable improvement in
patient - reported outcome in
FECD patients . -
pubmed
Microscopic studies revealed that , in incompatible interactions , posthaustorial
hypersensitivity reaction was the most prevalent but not exclusive plant defense response in
Mv Hombar , and fungal growth was mostly arrested during haustorium formation or in the early stages of colony development . -
pubmed
Central vein stenosis is a common problem in
patients on dialysis . -
pubmed
We describe three
patients with
left innominate vein stenosis who were known case of
chronic kidney disease on haemodialysis and had a left brachio - cephalic
fistula and presented with unilateral facial and
upper limb oedema . -
pubmed
STUDY POPULATION : All newly diagnosed
patients with
multiple myeloma (
MM ) , smoldering
MM ,
solitary plasmacytomas , and
plasma cell leukemia in Denmark are registered annually ; ~350
patients . -
pubmed
MAIN VARIABLES : The main registered variables at diagnosis are
patient demographics , baseline disease characteristics ,
myeloma - defining events , clinical complications , prognostics , first- and second - line treatments , treatment responses , progression free , and overall survival . -
pubmed
DESCRIPTIVE DATA : Up to June 2015 , 2,907 newly diagnosed
patients with
MM , 485
patients with smoldering
MM , 64
patients with
plasma cell leukemia , and 191
patients with solitary
plasmacytomas were registered . -
pubmed
A 20 - year - old
man was admitted with acute
respiratory failure . -
pubmed
The Effectiveness of Intraocular
Methotrexate in the Treatment of
Posterior Uveitis in
Behcet ' s Disease Patients Compared to Retrobulbar
Steroids Injection . -
pubmed
To evaluate the efficacy of intravitreal
methotrexate (
MTX ) compared to retrobulbar
triamcinolone acetonide (
TAA ) , in controlling posterior segment involvement and inducing remissions among
Behcet ' s disease (
BD )
patients . -
pubmed
31 adult BD male
patients with a mean disease duration of 5.45 years who presented with bilateral
posterior segment involvement were included . -
pubmed
No statistical differences were found between both treatment modalities ; however , based on clinical observations , intravitreal
MTX may ensure better control of inflammatory reaction and may encourage longer remission as compared to retrobulbar
TAA in
BD patients . -
pubmed
However , a large fraction of nonresponding
patients are
AR - V7 - negative . -
pubmed
DESIGN , SETTING , AND PARTICIPANTS : Peripheral blood was collected from
patients with
CRPC ( n=30 ) before initiation of a new line of systemic therapy . -
pubmed
[ Treatment Strategy and Results of Carotid Endarterectomy in
Chronic Renal Failure Patients ] . -
pubmed
Few reports have described carotid endarterectomy(CEA)for
chronic renal failure patients because of the unacceptable rate of perioperative
stroke and other morbidities . -
pubmed
RESULTS : Dialysis treatment was initiated due to
diabetes in 4
patients and
renal sclerosis in 2
patients . -
pubmed
In all the
patients ,
heart vascular lesions and
arteriosclerosis risk factors were present . -
pubmed
MATERIALS AND METHODS : Follow - up data were collected from 722
patients undergoing radical cystectomy for
urothelial carcinoma of the bladder ( UCB ) between 2004 and 2014 . -
pubmed
All
patients with suspected
bladder tumors were eligible for study inclusion . -
pubmed
CONCLUSIONS : Our results showed that efficacy and safety of the monopolar and bipolar methods seems to be comparable in
patients with
bladder tumors . -
pubmed
biting midges and can cause abortions and
congenital malformations in ruminants and milk drop in dairy
cattle . -
pubmed
BACKGROUND : Palliative systemic therapy is frequently underutilized in
patients with advanced
non - small - cell lung cancer (
NSCLC ) , for many reasons . -
pubmed
PATIENTS AND METHODS : With ethics approval , we analyzed ESAS scores at initial oncology consultation for 461
patients with advanced
NSCLC seen at The Ottawa Hospital Cancer Centre from 2009 to 2012 . -
pubmed
CONCLUSIONS : Overall , this demonstrates a novel role for the ESAS as a prognostic tool that could complement existing patient assessment models , such as Eastern Cooperative Oncology Group performance status , in the development of optimal treatment plans and estimation of survival , in
patients with advanced
lung cancer . -
pubmed
Currently no treatments exist for preterm
infants with diffuse
white matter injury (
DWMI ) caused by
hypoxia . -
pubmed
We demonstrate that
hypoxia activates the ISR in primary
mouse oligodendrocyte precursor cells ( OPCs ) in vitro and that genetically inhibiting the ISR in differentiating OPCs increases their susceptibility to in vitro
hypoxia . -
pubmed
We also show that a well - established in vivo mild chronic
hypoxia ( MCH )
mouse model and a new severe acute
hypoxia (
SAH )
mouse model of
DWMI activates the initial step of the ISR . -
pubmed
This study was conducted on 30
OLP patients and 30 healthy individuals . -
pubmed
Unstimulated saliva flow was significantly lower in
OLP patients ( P = 0.0001 ) . -
pubmed
Lungs represent the essential part of the
mammalian respiratory system , which is reflected in the fact that
lung failure still is one of the leading causes of morbidity and mortality worldwide . -
pubmed
Using these approaches , here we identify the earliest preclinical
AD stage in
subjects from the ADNI and BioFINDER cohorts . -
pubmed
Therefore , the aim of the present study was to propose a new
murine model of
BPH /
prostatitis induced by intraurethral injection of LPS . -
pubmed
Participants weight gain / loss at 24 months was defined as any value that was either above / below the weight value recorded at baseline . -
pubmed
Neuropathological lesions in terminally ill transgenic
mice were similar to
scrapie - infected wt controls , but less severe . -
pubmed
In addition ,
2 - AP treatment significantly decreased mortality in a
mouse model of
pulmonary fibrosis . -
pubmed
BACKGROUND : Neuraxial anesthesia improves components of the Virchow 's
triad (
hypercoagulability ,
venous stasis , and
endothelial injury ) which are key pathogenic contributors to
venous thrombosis in surgical
patients . -
pubmed
We therefore tested the primary hypothesis that neuraxial anesthesia reduces the incidence of 30 - day
VTE in
adults recovering from orthopedic surgery . -
pubmed
CONCLUSIONS : Neuraxial anesthesia appears to provide only weak
VTE prophylaxis , but can be offered as an adjuvant to current thromboprophylaxis in high - risk
patients . -
pubmed
METHODS : In a longitudinally cohort study , 107 formerly preeclamptic
women were assessed for traditional risk factors (
insulin resistance ,
obesity ,
dyslipidemia ,
hypertension , and
microalbuminuria ) of
metabolic syndrome ( World Health Organization criteria ) at two time points : at 3 - 30 months postpartum ( visit 1 ) and 24 - 65 months later ( visit 2 ) . -
pubmed
Pooled gene - trap mutagenesis of
haploid human HAP1 cells has proven to be a formidable tool for revealing genes involved in the
infection process for a suite of
human pathogenic viruses . -
pubmed
tuberculosis H37Rv
strain identified five active druglike compounds which were further profiled against patient - derived
M. - pubmed
The compound was shown to possess low toxicity for
mice ( LD50 = 900.0 + - 83.96 mg / kg ) and to be similarly efficacious to
etambutol , in the
mouse model of
drug - sensitive tuberculosis , and to
neurotoxic cycloserine in
mice infected with
MDR tuberculosis . -
pubmed
These practices are essential in
swine production , especially for highly infectious agents such as
porcine reproductive and respiratory syndrome virus (
PRRSv ) . -
pubmed
bovis
infections will be an important component of the strategy employed to eradicate
bovine TB from NZ livestock and wildlife . -
pubmed
The discovery of endophytic
Bt strains opened new perspectives for studies aimed at the control of sap - sucking insects , such as the
Asian citrus psyllid Diaphorina citri Kuwayama ( Hemiptera : Liviidae ) , a vector of " Candidatus Liberibacter spp . -
pubmed
In this study , translocation of endophytic Bt
strains in
citrus seedlings inoculated with
Bt suspension delivered by soil - drench , and their systemic pathogenicity to
D. - pubmed
Serum
Thiol - Disulphide Levels in
Epileptic Pediatric
Patients . -
pubmed
OBJECTIVE : The aim of this study was to determine serum levels of
thiol and
disulfide in
epileptic pediatric
patients . -
pubmed
METHODS : Ninety
patients , 54
epilepsy and 36 controls were included in the study . -
pubmed
CONCLUSION : We demonstrated a meaningful relationship between oxidative stress markers and
epilepsy in pediatric
patients . -
pubmed
We discuss here another
patient diagnosed with primary
cutaneous T - cell LBL at our institute . -
pubmed
This
patient was initially misdiagnosed as having
peripheral T - cell lymphoma NOS . -
pubmed
We believe that this presentation of
T - LBL is underreported , and many
patients are likely misdiagnosed as having high - grade
cutaneous T - cell lymphomas . -
pubmed
Two groups of six
Wistar rats anesthetized with
ketamine 200 mg / kg
body weight were used . -
pubmed
The lack of immunocompetent small animal models for
hepatitis C virus (
HCV ) has greatly hindered the development of effective vaccines . -
pubmed
Using rodent hepacivirus (
RHV ) , a homologue of
HCV that shares many characteristics of
HCV infection , we report the development and application of a novel RHV/ outbred
rat model for
HCV vaccine development . -
pubmed
Mekong
schistosomiasis caused by
Schistosoma mekongi is a public health problem that occurs along the border between southern Laos and northern Cambodia . -
pubmed
Our results demonstrate that : ( i ) a large fraction of cationic and non - ionic , but not anionic fMWCNT become trapped at the luminal brain endothelial cell membrane ; ( ii ) despite high cell association , fMWCNT uptake by brain endothelial cells is low ( & lt;1.5 % ID ) and does not correlate with BBB translocation , ( iii ) anionic fMWCNT have highest transport levels across an in vitro model of the
human BBB compared to non - ionic or cationic nanotubes ; and ( iv ) fMWCNT are not toxic to hippocampal neurons at relevant abluminal concentrations ; however , fMWCNT charge has an effect on
carbon nanotube
neurotoxicity at higher fMWCNT concentrations . -
pubmed
This quantitative combination of microscopy and spectroscopy , with cellular assays , provides a crucial strategy to predict brain penetration efficiency and
neurotoxicity of unlabelled MWCNT and other nanoparticle technologies relevant to
human health . -
pubmed
Taxane - induced
peripheral neuropathy and quality of life in
breast cancer patients . -
pubmed
METHODS : OST measurements were performed in the metacarpophalangeal , proximal intraphalangeal and wrist joints of 168
RA patients and 114 controls . -
pubmed
Additionally , the expansion of indications for
ALT which included the implementation of
ALT for
patients with
liver cancer and
ALT for
patients with
liver cirrhosis was discussed . -
pubmed
Prosthetic rehabilitation plays a crucial role in restoring
patients with
facial defects to normalcy . -
pubmed
This rare case report of a
patient with partial
lip necrosis describes her functional , mechanically retained prosthetic rehabilitation , which improved phonetics , esthetics , and function without the need of additional retentive features , increasing convenience and ease of use by the patient and at the same time cutting down cost . -
pubmed
Zika virus (
ZIKV ) was responsible in 2015 to 2016 for a major epidemic in South America and was associated in some cases with
neurological impairments . -
pubmed
Our observations suggest a complex interplay between
ZIKV and the BBB , which may trigger local
inflammation , leukocyte recruitment , and possible
cerebral vasculature impairment . -
pubmed
IMPORTANCE
Zika virus (
ZIKV ) can be associated with
neurological impairment in children and adults . -
pubmed
These results were also observed in a
mouse model of
ZIKV infection . -
pubmed
In this clinical trial , the effect of
Turmacin on
knee joint discomfort in healthy
adults subjected to strenuous physical activity was evaluated . -
pubmed
Giardia intestinalis is a
human parasite that causes a
diarrheal disease in developing countries . -
pubmed
MATERIALS - METHODS :
Patients who were admitted with any kind of
LUTS and diagnosed with
posterior compartment defects were retrospectively analyzed at urogynecology units of 2 different tertiary referral centers . -
pubmed
Patients were included in the analysis if they had isolated
posterior vaginal compartment defects with no clinically significant
anterior and apical compartment defects . -
pubmed
The control group consisted of
patients with no
pelvic organ prolapse (
POP ) . -
pubmed
RESULTS : Of the 340
women with posterior
POP , 280 were excluded from the analysis due to combined anterior and/or apical POP with posterior POP and stage 4
POP . -
pubmed
When we compared the symptoms between the control group and the remaining 60
patients with isolated posterior
POP , there was a statistically significant difference in urge , frequency ,
nocturia ,
abnormal emptying , vaginal winding , difficult stool passage ( p = 0.031 , p < 0.001 , p < 0.001 , p = 0.022 , p = 0.041 , and p = 0.039 , respectively ) . -
pubmed
One hundred three
patients with biopsy - proven
MM who underwent WBLDCT were retrospectively enrolled . -
pubmed
Patients with lesions > 10 mm showed an odds ratio ( OR ) of 29.8 ( 95%CIs 3.8 - 230.5 ) to develop at least one
fracture . -
pubmed
WBLDCT represents a reliable imaging - based tool for proper management of
MM patients , showing that diffuse form or small lytic lesions may deserve a less frequent follow - up . -
pubmed
Effect of granulocyte
chalone on acute and
chronic granulocytic leukaemia in
man . -
pubmed
This study reports results from the first clinical tests in which 7
patients with
myeloid leukaemia ( 5 acute and 2
chronic leukaemias in metamorphosis ) were treated from 4 to 45 days with granulocyte
chalone , the tissue - specific endogenous inhibitor of granulopoiesis . -
pubmed
Inhibition of leukaemic growth was distinct in 6 of the 7
patients ; in 5 cases the inhibition was followed by acutal regression of the
leukaemia , lasting up to several months in the absence of any maintenance therapy , and in one case the treatment led to a complete remission . -
pubmed
This study shows that granulocyte
chalone is biologically active against
myeloid leukaemia in
man , but not that the therapeutic value of the impure
chalone is superior to modern cytostatic drugs . -
pubmed
[ Effectiveness of a Bulgarian vaccine against
Marek ' s disease in
broilers ] . -
pubmed
Nine
goats assigned to three groups were given a jugular infusion of
[ 14C ] 3MI ( 0.02 to 0.03 g of
3MI / kg of
body weight containing 0.5 muCi / kg of
body weight ) for 1.5 hours to induce
acute pulmonary edema . -
pubmed
Goats pretreated with
PB had more severe
lung lesions than did
3MI controls . -
pubmed
We studied the smoking habits of 114
patients with
senile disciform degeneration of the macula . -
pubmed
We advise all
patients with
disciform degeneration to stop smoking . -
pubmed
The authors report successful surgical treatment of a
patient with an
anterior communicating artery aneurysm associated with absence of all of the left cervical carotid arteries . -
pubmed
Freeze -
fracture of capillary endothelium in
rat brain . -
pubmed
A carotid endarterectomy with removal of the
thrombus and intima was performed with satisfactory recovery of the
patient . -
pubmed
Plasma
zinc levels were measured in both healthy and
diabetic individuals having an age range of 10 - 93 years . -
pubmed
No significant differences in plasma
zinc concentrations were found between males and females in either healthy or
diabetic individuals . -
pubmed
Hypothermia causes adult - like retention
deficits of prior learning in infant
mice . -
pubmed
Nine - day - old S - W
mice receiving deep body
hypothermia or
hyperthermia immediately after escape training were retested 1 or 24 hr later . -
pubmed
Hyperthermia had no effect , with the
mice demonstrating retention of the escape response at both retest intervals . -
pubmed
[ Preliminary results of the use of an antimycotic drug ,
clotrimazole (
bis - phenyl -( 2 - chlorophenyl )- 1 - imidazoly - methane :
BAY b 5097 ) in local administration for therapy of
vaginitis caused by
Candida albicans and by
Trichomonas vaginalis ] . -
pubmed
Cardiac microdialysis measurement of extracellular
adenine nucleotide breakdown products during regional
ischemia and reperfusion in
canine heart : protective effect of
propranolol against
reperfusion injury . -
pubmed
Lhermitte 's sign , as part of
cisplatin - related
neurotoxicity , was observed in four
patients , with
ovarian or lung cancer , simultaneously with
peripheral neuropathy , after a dose of 375 - 700 mg / m2 . -
pubmed
Periodontal and restorative treatment in a
patient with
familial gingival fibromatosis : a case report . -
pubmed
No raised levels ( less than 18 unit ( U ) ml-1 ) of the antigen were found in the serum of 220 normal
individuals or of
patients with
germ cell tumours ( n = 6 ) ,
granulosa theca cell tumour ( n = 1 ) , gastric
carcinomas ( n = 10 ) and colo - rectal
carcinomas ( n = 8) . -
pubmed
The body
weight gain , total feed intake , and feed conversion were determined for male and female
chickens between 3 and 7 wk of age . -
pubmed
Here we report that milk - transmitted
MuMTV also delays the development of the
acute erythroleukemia induced by
Friend leukemia virus ( FLV ) , and retards , or prevents in some cases , the development of long - term
lymphomas caused by its helper component . -
pubmed
A number of studies have shown that
Chlamydia trachomatis bacteria are important pathogens in
urogenital tract infections , such as acute
urethritis ,
acute epididymo - orchitis in male patients and
pelvic inflammatory disease in female patients . -
pubmed
Altogether 38 tarsorraphies were carried out to 19
patients with
corneal epithelial defects resistant to conventional therapy . -
pubmed
The main operative indications were lagothalmos ,
dry eyes and
inadequate blinking ( 6
patients ) . -
pubmed
An epizootic of feline
infectious peritonitis in a captive cheetah population during 1982 - 1983 served to focus attention on the susceptibility of the cheetah (
Acinoyx jubatus ) to
infectious disease . -
pubmed
A 37 - year - old
man with such a
tumor in his right eyebrow is reported , and the relevant literature is reviewed . -
pubmed
In the acute phase of the disease there was : 1 ) a fall in serum
triglycerides in
patients with bacteremic
pneumococcal disease and in
patients with no defined aetiology ( p less than 0.01 and less than 0.005 , respectively ) . -
pubmed
Diagnosis and successful treatment of
diarrhoea in
horses caused by immature small strongyles apparently insusceptible to anthelmintics . -
pubmed
It is , therefore , concluded that both the histological structures and cell morphology have close relationships with cell kinetics in the
human gastric cancers . -
pubmed
Tumors from three separate cohorts of
patients were studied as follows : population A , 62 primary
breast cancers from 1983 ; population B , 72 primary
lesions stored from 1976 to 1983 ; and population C , 23
patients with
metastases , treated with hormonal therapy . -
pubmed
Some physiological responses to
anoxia in the
great plains toad ,
Bufo cognatus . -
pubmed
Intramuscular
methohexital for rapid induction of short duration sleep in the EEG laboratory : a study of forty - four
hyperkinetic children . -
pubmed
Severe
hepatic damage with submassive
necrosis induced in
rats by an intraperitoneal injection of a single dose of
galactosamine hydrochloride was studied . -
pubmed
Parathyroid
hyperplasia can sometimes be controlled medically , but the only definitive treatment for
hyperplasia and parathyroid
adenomata is surgery , to the extent indicated , in these often
critically ill patients with this
multisystem disease . -
pubmed
[ Dietary intake and urinary excretion of various mineral substances in
patients with
hypertension and
ischemic heart disease ] . -
pubmed
In
patients with
coronary heart disease ,
potassium was eliminated in a greater amount and
calcium in a less amount as compared with the amounts supplied with the diet . -
pubmed
The most demonstrable retention of
sodium was recorded in
patients with stage III essential
hypertension . -
pubmed
Fifty - five
infants participated in a double - blind study of
indomethacin therapy for the closure of
patent ductus arteriosus . -
pubmed
For those
infants who survived and returned for follow - up at approximately 1 year of age , there was no significant difference between the control ( n = 17 ) and
indomethacin ( n = 13 ) groups with respect to physical growth , Bayley scores ,
respiratory infection , abnormal eye ground ,
neurological defects , and abnormal EEG . -
pubmed
The effects of blended Chinese traditional medicines applied for
diabetes mellitus were studied on the pattern of action to the
glucose tolerance curves in genetically
diabetic KK - CAy
mice . -
pubmed
Localization of a
tumor suppressor gene associated with progression of
human prostate cancer within a 1.2 Mb region of 8p22 - p21.3 . -
pubmed
Human prostate cancers frequently show loss of heterozygosity at loci on the short arm of chromosome 8 . -
pubmed
Peripheral neurotoxicity of
taxol in
patients previously treated with
cisplatin . -
pubmed
METHODS : Twenty - two
patients affected by a
relapse of
cisplatin - treated
ovarian cancer were examined clinically and neurophysiologically to determine the evolution of
taxol - induced peripheral somatic and autonomic
neurotoxicity and the possible cumulative effect of a combination of
taxol and
cisplatin . -
pubmed
RESULTS : No
patients were excluded from the study because of unacceptable
toxicities of any kind . -
pubmed
The serial examinations demonstrated that
taxol induced onset of ( or worsening of preexisting )
neuropathic symptoms and signs in almost all the
patients . -
pubmed
It appears that a cumulative , but not dose - limiting ,
neurotoxic effect occurs using
taxol in
patients previously treated with
cisplatin . -
pubmed
[ Immunologically mediated
thrombocytopenia in
Legionella pneumophila pneumonia ] . -
pubmed
Leuprolide acetate was used to produce a constant hypoestrogenic environment in a young
patient with histologically confirmed
adenomyosis . -
pubmed
Conservative medical therapy was initiated because of the
patient 's complaint of severe
dysmenorrhea coupled with her strong desire for uterine conservation . -
pubmed
Dystrophic form of
inherited epidermolysis bullosa in a
dog ( Akita Inu ) . -
pubmed
We report a
dog with
dystrophic epidermolysis bullosa . -
pubmed
japonicus Temminck , had a 3 - year - history of
ulcers and
scars over the pressure areas on the limbs , and
dystrophic nails , since the age of 1 year , which corresponds to early adulthood in
humans . -
pubmed
BACKGROUND : The short- and long - term effects of
levodopa (
L - dopa ) , an oral dopaminergic prodrug , were assessed in
patients with severe
left ventricular dysfunction . -
pubmed
The remaining 22
patients with favorable hemodynamic response to
L - dopa ( increase in cardiac index ,
stroke volume index , reduction in total systemic resistance ) were randomized in a nonblinded fashion to the conventional ( 11
patients ) or conventional plus
L - dopa ( 11
patients ) treatment groups . -
pubmed
The cause of
congestive heart failure was primary
dilated cardiomyopathy in 11
patients and
ischemic heart disease in 9
patients . -
pubmed
CONCLUSIONS : The addition of
L - dopa to conventional therapy has beneficial short- and long - term effects in
patients with severe
left ventricular dysfunction . -
pubmed
Short - term ( 6 weeks ) treatment of 15 anti - ANT antibody - positive
IDC patients with
prednisone was of beneficial effect . -
pubmed
Some considerations regarding the use of
amino acid racemization in
human dentine as an indicator of age at
death . -
pubmed
[ The normal tear fluid and decreased tearing in
patients with
Sjogren ' s disease and
Sjogren ' s syndrome . -
pubmed
MATERIAL AND METHODS : An outcome based study was conducted of 51
patients undergoing construction of a vaginal wall sling for genuine
stress incontinence or intrinsic
sphincteric deficiency . -
pubmed
Despite long - term resolution of
stress incontinence in 92 % of those with genuine
stress incontinence and 75 % with intrinsic
sphincter deficiency ,
postoperative urge incontinence was the single most important factor affecting
patient satisfaction ( p = 0.001 ) . -
pubmed
Although preoperative leak point pressure correlated with resolution of
stress incontinence , no preoperative demographic factors , symptoms or urodynamic parameters could reliably predict postoperative
patients satisfaction . -
pubmed
Langerhans and other immunocompetent cells in
vocal cord epithelial hyperplastic lesions of
patients with
chronic laryngitis . -
pubmed
The aim of the study was to evaluate the intraepithelial and stromal density of Langerhans cells and lymphoid infiltrate in different stages of
carcinogenesis in vocal cord biopsies of 24 randomly selected
patients with
chronic laryngitis . -
pubmed
Here we report a method for extracting DNA from dried blood
spots on filter paper which is capable of detecting one
Plasmodium falciparum and two
Plasmodium vivax parasites / microliter of whole blood by nested PCR without compromising the simplicity of specimen collection or DNA extraction . -
pubmed
We describe an Italian
boy with this disease whose
mental retardation was relatively mild and whose
renal tubular acidosis had only a distal component . -
pubmed
Establishment and preliminary characterization of
human malignant mesothelioma cell lines . -
pubmed
The paucity of well - characterized in vitro
human models and the consequent shortage of experimental pharmacological studies on
mesothelioma reduce the success of its clinical management . -
pubmed
It is well known that established
human cell lines represent a rapid and advantageous system for in vitro studies of several diseases , such as
mesothelioma . -
pubmed
Thus , the aim of our study was to establish and characterize a panel of selected
human malignant mesothelioma cell lines in order to highlight the biology of this
tumor and to test the effectiveness of new antiproliferative compounds . -
pubmed
During the last year , we collected 10
pleural effusion samples from
patients with diagnosed and pharmacologically untreated
mesothelioma . -
pubmed
This systematic review assesses six experimental studies into the mechanism of placebo analgesia in
human subjects suffering from clinical
pain or experimentally induced
ischaemic arm pain . -
pubmed
After the initial assessment of elderly
patients suspected of having
malabsorption , as discussed in the first of this pair of articles , more specific investigations may be necessary . -
pubmed
Acute
toxicity and sublethal effects of white
phosphorus in
mute swans ,
Cygnus olor . -
pubmed
To estimate the
toxicity of P4 to swans and compare the toxic effects to those of
mallards (
Anas platyrhynchos ) , we dosed 30
juvenile mute swans (
C. - pubmed
Most
swans took 1 to 4.5 days to die in contrast to the few hours normally required in mallards and
death appeared to be related more to
liver dysfunction than to
hemolysis . -
pubmed
Considering that over 80 % of
human malignant tumors derive from epithelial cells , we studied the effect of
As2O3 on HPV 16 DNA - immortalized
human cervical epithelial cells (
HCE16 / 3 cells ) in vitro . -
pubmed
OBJECT : In this study the authors sought to estimate the frequency , seriousness , and delay of rebleeding in a homogeneous series of 20
patients whom they treated between May 1987 and May 1997 for
arteriovenous fistulas (
AVFs ) that were revealed by
intracranial hemorrhage (
ICH ) . -
pubmed
METHODS : Presenting symptoms in the 20
patients ( 17
men and three
women , mean age 54 years ) were acute
headache in 12
patients ( 60 % ) , acute
neurological deficit in eight ( 40 % ) ,
loss of consciousness in five ( 25 % ) , and generalized
seizures in one ( 5 % ) . -
pubmed
Results of the clinical examination were normal in five
patients and demonstrated a
neurological deficit in 12 and
coma in three . -
pubmed
A diagnosis of
AVF was made with the aid of angiographic studies in 19
patients , whereas it was a perioperative discovery in the remaining
patient . -
pubmed
Seven
patients ( 35 % ) presented with acute worsening during this delay due to radiologically proven early
rebleeding . -
pubmed
Our novel whole - body scintigraphic method for prospective dosimetry was compared with the 5 h urine collection technique in 10
patients with
bone metastases . -
pubmed
The total administered activity of
153Sm - EDTMP predicted on a 2 Gy bone marrow dose varied between 35 and 63 % of the standard recommended regimen of 37 MBq.kg-1 and
pain relief was experienced by eight of the ten
patients . -
pubmed
Administration of
153Sm - EDTMP according to the supplier 's recommendations would have delivered bone marrow doses of 3.27 - 5.90 Gy in our
patients , doses at which
myelotoxicity would have been anticipated . -
pubmed
Detection of a radiographically occult
fracture of the lateral palmar process of the distal phalanx in a
horse using computed tomography . -
pubmed
A
horse with a suspected
injury of the distal phalanx was examined using radiography at day two and 19 after the onset of the
lameness , with no definite diagnosis . -
pubmed
This report emphasizes the value of computed tomography in diagnosing a geometric complicated nonarticular oblique
fracture of the palmar process of the pedal bone in a
horse . -
pubmed
This study showed that recombinant protein antigens can be used for serological tests to detect
bovine lentivirus infection in Australia . -
pubmed
Acute ischemic stroke in a young
woman with the
thiamine - responsive
megaloblastic anemia syndrome . -
pubmed
Enterococcus faecalis induces the synthesis of at least 42 proteins during 24 h of
glucose starvation . -
pubmed
METHODS : The
patients were enrolled at random in the two surgical groups , provided that a radical excision of the
tumour , with only two limits : the level of the lesion from the anal verge and the presence of a severe
incontinence instrumentally proven . -
pubmed
The effectiveness of aerosolized
amphotericin B as prophylaxis against
aspergillosis in
neutropenic patients needs to be evaluated in a large clinical trial . -
pubmed
Activated platelets in
patients with severe
hypertriglyceridemia : effects of
triglyceride - lowering therapy . -
pubmed
This study was designed to compare the in vivo platelet activation status between
patients with severe
hypertriglyceridemia and age- and sex - matched control subjects , and to evaluate the effects of
triglyceride - lowering therapy . -
pubmed
Sixteen
patients with
primary hypertriglyceridemia were included in a double - blind , placebo - controlled cross - over trial with 400 mg
bezafibrate once daily . -
pubmed
In conclusion ,
patients with
hypertriglyceridemia have an increased in vivo platelet activation status , which can be improved by
bezafibrate therapy . -
pubmed
Echovirus 11 may cause life - threatening
infections in small infants . -
pubmed
Long - term
valproate and
lamotrigine treatment may be a marker for reduced growth and bone mass in
children with
epilepsy . -
pubmed
PURPOSE : To determine whether long - term treatment with
valproate (
VPA ) and/or
lamotrigine (
LTG ) in
children with
epilepsy is associated with altered growth and/or bone metabolism . -
pubmed
A total of 111 female
patients with
stroke were selected and with questionnaires filled in and blood samples collected . -
pubmed
RESULTS :
Women using pills had a higher risk developing
hemorrhagic than
ischaemic stroke ( OR = 3.03 , P & lt ; 0.05 ) , comparing with those never used pills . -
pubmed
Prolonged
immune deficiency following allogeneic stem cell transplantation : risk factors and complications in adult
patients . -
pubmed
Treatment of
chronic pleural effusion with pleuroperitoneal shunts in
dogs : 14 cases ( 1985 - 1999 ) . -
pubmed
OBJECTIVE : To describe complications and outcome associated with chronic
nonseptic pleural effusion treated with pleuroperitoneal shunts in
dogs . -
pubmed
PROCEDURE : Medical records at 4 veterinary schools were examined to identify
dogs with chronic
nonseptic pleural effusion that were treated by use of a pleuroperitoneal shunt between 1985 and 1999 . -
pubmed
RESULTS : 10 of 14
dogs had
idiopathic chylothorax , and 4 had an identified disease . -
pubmed
All but 1
dog with
idiopathic chylothorax and 1
dog with
chylothorax from a
heart base tumor had unsuccessful thoracic duct ligation prior to pump placement . -
pubmed
Eight of 11
dogs with long - term follow - up developed complications ; the overall mean survival time and the interval in which
dogs remained free of clinical signs of
pleural effusion were 27 months ( range , 1 to 108 months ) and 20 months ( range , 0.5 to 108 months ) , respectively . -
pubmed
CONCLUSIONS AND CLINICAL RELEVANCE : Pleuroperitoneal shunts can effectively palliate clinical signs associated with intractable
pleural effusion in
dogs . -
pubmed
We are identifying proteins of interest by coring autoantigenic protein
spots from two - dimensional ( 2 - D ) gels of
rat sperm extracts and microsequencing them by mass spectrometry . -
pubmed
DATA ANALYSIS : Because most common diseases including
sepsis have been shown to be influenced by inherited differences in our genes , completion of the
Human Genome Project and the concomitant publication of the human single nucleotide polymorphism map both contribute to change our approach to medicine . -
pubmed
METHODS : In a prospective cross - sectional study , 91 chronic
HD patients and 18 anaemic controls with normal renal function were recruited . -
pubmed
METHODS : We assessed 297 consecutive
patients with clinical stage I
NSCLC who underwent surgical resection at Toneyama National Hospital from 1985 to 1998 . -
pubmed
These differences were also observed in
patients with pathologic stage I or II
tumors but not in those with pathologic stage III or IV
tumors . -
pubmed
METHOD : We chose to study a population with a primary diagnosis of
myofascial pain of the jaw muscles or atypical
facial pain and excluded
patients with
disc displacement , acute
arthritis and severe
arthrosis . -
pubmed
Within nine months , 124 consecutive
patients with
FAM ( n=108 ) or
AFP ( n=16 ) were referred to the departments of maxillary surgery , dentistry or neurology of two interdisciplinary academic
pain centers . -
pubmed
RESULTS : The group of FAM-/AFP -
patients according to our inclusion-/exclusion - criteria presenting with a high
pain intensity showed more psychosocial withdrawal ( p=0.013 ) , a worse self - rated psychological status ( p=0.033 ) and a trend towards more
somatization ( p=0.093 ) than patients with lower
pain intensity . -
pubmed
Chronic mild stress in
rodents has been proposed to model some of the environmental factors that contribute to the induction of
depressive disorders in
humans . -
pubmed
Therefore , the potential contribution of a reduction in
body weight to the chronic mild stress - induced alterations in brain reward function was examined in a separate group of food - restricted
rats . -
pubmed
Quantitative magnetic resonance imaging ( MRI ) studies in
patients with
schizophrenia have shown reliable deficits in global tissue volume as well as some regionally specific changes , particularly in the temporal and frontal lobes . -
pubmed
[ Modification of viscosity of saliva in
dogs following
disorders of functional conditions of the central nervous system ] . -
pubmed
[ Anatomoclinical findings in spontaneous prolonged
epilepsy in a
Patas monkey ] . -
pubmed
[ Effect of antibiotics on experimental
tularemia in the
mouse ] . -
pubmed
[ Spontaneous
arterial sclerosis in
animals ] . -
pubmed
The group consisted of 126
patients ( mean age : 43.1 years ) with the clinical diagnosis of
anal fistula . -
pubmed
The
patient groups were compared pre- and postoperatively by repeated clinical assessments of cerebral excitation according to a modified Objective
Pain Discomfort Scale , OPDS . -
pubmed
METHODS : IHb of the fundic mucosa was measured in 108
patients with various
gastric diseases ( group 1 ) , and values were compared between
H. - pubmed
Fifteen
patients with
H. - pubmed
Of the 10
children aged 6 - 17 years , all ( 100 % ) fulfilled criteria for both
post - traumatic stress disorder (
PTSD ) and
major depression with
suicidal ideation . -
pubmed
CONCLUSION : High - risk pregnancies in liver - transplanted
women are generally associated with good outcomes , although an increased rate of
preterm labor ,
intrauterine infections ,
anemia , and
cholestasis were observed . -
pubmed
Gonadoblastomas in 5
patients with
46,XY gonadal dysgenesis . -
pubmed
We describe five
patients with
46,XY gonadal dysgenesis who developed
gonadoblastomas ,
dysgerminomas , a
mature teratoma , and a
testicular intraepithelial neoplasia . -
pubmed
Fibrosarcoma in
yellow perch ,
Perca flavescens ( Mitchill ) . -
pubmed
We made an attempt to study the cytological changes in the buccal mucosal cells of
iron deficiency anemia ,
patients . -
pubmed
Buccal mucosal cells were scraped from 40
iron deficiency anemia patients and were subjected to morphometric analysis . -
pubmed
The phage receptor was present in the outer core of
strains of many other
Y. - pubmed
enterocolitica serotypes , but also in some
Yersinia intermedia strains . -
pubmed
In
subjects experiencing
fatigue when they achieved 50 - 75 % of target heart rate ( THR ) , or those who failed to achieve their THR ,
atropine was administered in doses of 0.5 mg per minute until the test conclusion ( positive test results or target heart rate achieved ) or until a maximum dose of 2 mg was administered . -
pubmed
Time course of inhibition and facilitation in
patients with
schizophrenia . -
pubmed
RESULTS : At short RSIs of 500 ms ,
chronically ill state hospital
schizophrenia patients failed to exhibit
NP . -
pubmed
CONCLUSIONS : These results suggest that
schizophrenia patients are better able to inhibit irrelevant stimuli that are immediate , but the sustainment of inhibition across very short time intervals ( 500 ms ) may fade compared to controls . -
pubmed
Our findings demonstrate the ability of the cooled CCD camera to sensitively and non - invasively track the location , magnitude and persistence of luciferase gene expression in
human prostate cancer mouse models . -
pubmed
Identical
wounds from 3 - month - old , untreated
rats served as controls . -
pubmed
Histologic analysis showed a marked delay in several aspects of
wound repair in the aged
rats in comparison with that noted in the younger
animals . -
pubmed
However , the levels of mRNA corresponding to these secreted proteins appeared to be reduced in
wound tissue from aged
rats . -
pubmed
CONCLUSION : In the nonoperative management of
children with
perforated appendicitis , admission CT findings demonstrating disease beyond the right lower quadrant correlate with treatment failure . -
pubmed
In the study , the level of
measles immunity was measured among 1,405 military conscripts belonging to the first childhood immunization cohorts that were offered two doses of the
measles ,
mumps and
rubella vaccine . -
pubmed
MATERIALS AND METHODS : Clinical records of all
patients with
head and neck schwannomas treated at our department from April 1995 to July 2005 were retrospectively reviewed . -
pubmed
All
facial schwannoma patients suffered
postoperative facial palsy with only partial resolution ( mean final House - Brackman grade , 3.25/6 ) . -
pubmed
Among
non - facial schwannoma patients , postoperative
neural deficit occurred in 12 with partial to complete resolution in 7 . -
pubmed
Although
snakebites are frequently seen in small animal practice in South Africa , boomslang (
Dispholidus typus )
bites are infrequent due to their shy habits . -
pubmed
One of the
dogs developed severe adverse reactions to the antivenom , including
vomiting ,
dyspnoea and
nystagmus , which responded well to intravenous
cortisone and symptomatic treatment . -
pubmed
Trafficking in
human beigns (
THB ) is recognized as a global public health issue as well as a violation of
human rights . -
pubmed
AIMS : Pathogenicity of
Exobasidium vexans , causal agent of
blister blight of tea , was studied in 30 commercially cultivated
tea varieties by analysing the antigenic patterns of host and pathogen using immunological techniques . -
pubmed
An open - label trial of
riluzole , a
glutamate antagonist , in
children with treatment - resistant
obsessive - compulsive disorder . -
pubmed
Riluzole , a
glutamate antagonist , has theoretical support as an alternative pharmacological treatment and has demonstrated possible benefit in some open - label trials in
adults with
OCD . -
pubmed
METHODS : Six
subjects , ages 8 - 16 years , were enrolled in a 12 - week open - label trial of
riluzole for
OCD symptoms that had resisted prior treatments . -
pubmed
CONCLUSIONS :
Riluzole may be beneficial for
treatment - resistant OCD in young
subjects and seems well tolerated . -
pubmed
This is the first study to demonstrate dose related effects of
PAI-039 on increasing
thrombus resolution and inferior vena cava blood flow without adverse effects on anti - coagulation in a
rat stenosis model of
venous thrombosis . -
pubmed
Prevalence and identification of fungal DNA in the small intestine of healthy
dogs and
dogs with
chronic enteropathies . -
pubmed
The aim of this study was to evaluate the prevalence of fungal DNA in the small intestine of healthy
dogs and
dogs with
chronic enteropathies . -
pubmed
These results indicate a high prevalence and diversity of fungal DNA in the small intestine of both healthy
dogs and
dogs with
chronic enteropathies . -
pubmed
Of the 153,180
CHF patients , 37.2 % were
anemic . -
pubmed
After a minimal follow - up of 6 months , 46.8 % of
anemic patients died compared with 29.5 % of nonanemic
patients . -
pubmed
METHODS : A total of 182
patients with
facial nerve injury were reviewed . -
pubmed
Have changes in systemic treatment improved survival in
patients with
breast cancer metastatic to the brain ? -
pubmed
Newly developed systemic treatment regimens might lead to improved survival also in the subgroup of
breast cancer patients that harbour
brain metastases . -
pubmed
However , such treatment was performed nearly exclusively in those
patients with
brain metastases that belonged to the prognostically more favourable groups . -
pubmed
Nevertheless , the present results are compatible with the hypothesis that improved systemic therapy might contribute to prolonged survival in
patients with
brain metastases from
breast cancer . -
pubmed
Here , we analyzed in the blowfly
Calliphora vicina the visuomotor transformation from motion - sensitive neurons in the lobula plate [ V2 and vertical system ( VS ) cells ] onto premotor descending neurons [ descending neurons of the ocellar and vertical system ( DNOVS ) cells ] feeding into the motor circuit of the fly thoracic
ganglion . -
pubmed
Mild
hypohydration induced by exercise in the heat attenuates autonomic thermoregulatory responses to the heat , but not thermal pleasantness in
humans . -
pubmed
Hypohydration caused by exercise in the heat attenuates autonomic thermoregulation such as sweating and skin blood flow in
humans . -
pubmed
CASE : A 57 - year - old
women , underwent 8 years ago laparoscopic cholecystectomy for
acute cholecystitis . -
pubmed
Co
infection with Plasmodium and
helminth parasites is associated with significantly ( p & lt ; 0.001 ) higher
anaemia prevalence than single
infection with Plasmodium parasites . -
pubmed
They were selected
patients with normal uptake or a single
tumor . -
pubmed
Further studies are needed to address factors related to the observed effects of soy
isoflavones on
SBP and to verify the effect in
hypertensive patients . -
pubmed
Community - associated
methicillin - resistant
Staphylococcus aureus (
CA - MRSA ) infections are predominantly those affecting skin and soft tissues . -
pubmed
Isogenic hla - negative ( Deltahla ) strains caused
skin lesions in a
mouse infection model that were significantly smaller than those caused by wild - type
USA300 and
Newman strains . -
pubmed
Moreover ,
infection due to wild - type
strains produced
dermonecrotic skin lesions , whereas there was little or no
dermonecrosis in
mice infected with Deltahla
strains . -
pubmed
CONCLUSION : Acupuncture - moxibustion apparently relieves the symptoms of
xerophthalmia , promotes tear secretion and improves the life quality of
patients . -
pubmed
METHODS : For this study , first - ever
ischemic stroke patients who were admitted within 1 month of
stroke onset during the period of March 2002 through December 2008 were included . -
pubmed
Data on
ischemic stroke patients were collected which included : demographics , risk factors , treatment administered ,
stroke - related complications and 3 - month , 6 - month and 1 - year
death and disability . -
pubmed
RESULTS : Of the 2,683
patients included in this study , 366 ( 13.6 % ) had
AF . -
pubmed
In this group ,
valvular AF was observed in 153 ( 41.8 % )
patients . -
pubmed
Compared to
patients without
AF ,
patients with
AF were older ( 66.1 vs. 63.6 , p = 0.001 ) and had a higher NIHSS score on admission ( median 10 vs. 4 , p & lt ; 0.001 ) and more frequently suffered from
hemorrhagic transformation ( 7.3 vs. 2.8 % , p & lt ; 0.001 ) ,
pulmonary infection ( 27 vs. 10.6 % , p & lt ; 0.001 ) ,
urinary tract infection ( 8.5 vs. 3.0 % , p & lt ; 0.001 ) , acute
gastrointestinal tract hemorrhage ( 4.1 vs. 1.9 % , p = 0.008 ) , electrolyte disturbance ( 5.2 vs. 1.8 % , p & lt ; 0.001 ) ,
acute renal failure ( 1.1 vs. 0.5 % , p = 0.005 ) and
urinary incontinence ( 3.8 vs. 0.6 % , p & lt ; 0.001 ) during hospitalization . -
pubmed
The percentages of
patients with
AF who received oral anticoagulants were 3.3 % before
stroke onset and 14.2 % at discharge . -
pubmed
Moreover ,
patients with
AF had a higher proportion of disability ( determined as modified Rankin Scale score 3 - 5 ) in 3 - month , 6 - month and 1 - year follow - ups ( 46.6 , 41.9 and 37.6 vs. 29.1 , 24.0 and 19.3 % , respectively , p & lt ; 0.001 ) and higher case fatality in hospitalization , 3 - month , 6 - month and 1 - year follow - ups ( 10.1 , 25.5 , 29.1 and 34.0 vs. 2.0 , 7.4 , 8.8 and 11.6 % , respectively , p & lt ; 0.001 ) . -
pubmed
CONCLUSIONS :
Ischemic stroke patients with
AF have a poorer outcome , a higher frequency of
stroke - related complications and a higher case fatality than
patients without
AF . -
pubmed
Oral anticoagulants were underused in
AF patients . -
pubmed
RESULTS : In cases of incidental
meningioma , its location , size and radiological aspect , the
patient 's age , the eventual unknown symptoms and the multiplicity of the lesions must all be considered . -
pubmed
CONCLUSION : We recommend neurosurgical consultation for all
patients with an incidental
meningioma . -
pubmed
During injection in increments ( limited by
patient discomfort ) , the
patients were asked continually to quantify their
pain experience on a visual analog scale ( VAS ) and on a 0 - 3 verbal categorical rating scale ( VRS ) after 50 , 80 and 100 mL of infusion over a 20 minute period . -
pubmed
RESULTS :
PDPH occurred in 60 of 1,716
patients undergoing dural puncture ( 3.5 % ) . -
pubmed
The technique of repeated caudal saline injections is easy , rapid , and effective in providing the
patient with almost immediate
headache relief . -
pubmed
The activities of total
( 210 ) Pb in
caribou and
muskox bones were found to be 1 - 2 orders of magnitude higher than that of parent - supported
( 210 ) Pb indicating the potential for dating of bones of terrestrial mammals ( time elapsed since the
death of the
animal ) based on the excess
( 210 ) Pb method exists . -
pubmed
BACKGROUND AND IMPORTANCE : We report the case history of solitary
hypoglossal paraganglioma in a 64 - year - old
woman . -
pubmed
CLINICAL PRESENTATION : A 64 - year - old
woman presented with a short history of
dysphonia , occasional
dysphagia ,
tinnitus ,
altered taste , and unilateral left - sided
tongue wasting . -
pubmed
We report on a surgically resected
perineurioma of the falx cerebri in an 86 - year - old
woman . -
pubmed
Evaluate the early and long term surgical and functional results of the ileal pouch - reservoir ( IPAA ) in
patients with intractable
ulcerative colitis . -
pubmed
Scientific inquiry has provided incredible insight into the complex etiology of
weight gain but must be viewed as an interaction between a
human 's propensity to conserve calories for survival in a world with an abundance of it . -
pubmed
Natural killer cell mediated missing - self recognition can protect
mice from primary
chronic myeloid leukemia in vivo . -
pubmed
A novel bacterial
strain ,
YC7001(T ) , was isolated from the rhizosphere soil of
rice collected at Jinju , Korea , and was characterized using a polyphasic approach . -
pubmed
Cells of
strain YC7001(T ) were Gram - negative - staining , yellow - pigmented , rod - shaped , aerobic , heterotrophic and non - motile . -
pubmed
The DNA - DNA relatedness value of
strain YC7001(T ) with
C. - pubmed
The major
fatty acids of
strain YC7001(T ) were C(15:0 ) iso ,
C ( 16:1 ) omega5c and
C ( 17:0 ) iso 3 - OH . -
pubmed
The type
strain is
YC7001(T ) ( = KACC 14533(T ) = JCM 16595(T ) ) . -
pubmed
Does a nondipping pattern impact the right ventricle in
hypertensive patients ? -
pubmed
METHODS : This cross - sectional study included 189 recently diagnosed
hypertensive patients . -
pubmed
RESULTS : The dipping blood pressure pattern was found in 107 ( 57 % ) participants , whereas the nondipping pattern was present in 82 ( 43 % )
hypertensive patients . -
pubmed
Nanoparticle - based
clodronate delivery mitigates
murine experimental
colitis . -
pubmed
Altered diffusion tensor imaging measurements in aged transgenic
Huntington disease rats . -
pubmed
Rodent models of
Huntington disease (
HD ) are valuable tools for investigating
HD pathophysiology and evaluating new therapeutic approaches . -
pubmed
The first transgenic
rat model for
HD exhibits progressive late - onset
affective , cognitive , and motor impairments , as well as neuropathological features reflecting observations from
HD patients . -
pubmed
In this report , we contribute to the anatomical phenotyping of this model by comparing high - resolution ex vivo DTI measurements obtained in aged transgenic
HD rats and wild - type controls . -
pubmed
These changes are largely compatible with DTI findings in preclinical and clinical
HD patients . -
pubmed
We confirm earlier reports that
HD rats express a moderate neuropathological phenotype , and provide evidence of altered DTI measures in specific
HD - related brain regions , in the absence of pronounced morphometric changes . -
pubmed
Co - cultivation of the JM/102W
strain of
Marek ' s disease virus (
MDV ) with
reticuloendotheliosis virus (
REV ) resulted in the generation of a recombinant
MDV containing the
REV long terminal repeat ( LTR ) named the RM1
strain of
MDV , a
strain that was highly attenuated for oncogenicity but induced severe bursal and thymic
atrophy . -
pubmed
Susceptible
chickens were inoculated intra - abdominally at hatch with the viruses rMd5 - RM1 - LTR , rMd5 BAC parental virus , wild - type
strain Md5 , or strain RM1 of
MDV . -
pubmed
We present 2
patients with persistent
dysphagia after repair of
esophageal atresia that was caused by
EoE. -
pubmed
Effect of
1 , 25 ( OH ) 2 vitamin D3 on
glucose homeostasis and DNA damage in
type 2 diabetic mice . -
pubmed
AIMS : The purpose of the study was to examine the effect of
1 , 25 ( OH ) 2 Vitamin D3 supplementation on
type 2 diabetic (
T2DM )
mice . -
pubmed
MATERIALS AND METHODS : A total of 24
mice were taken and divided into three groups of control ;
diabetic and
diabetic +
vitamin D supplemented ones . -
pubmed
OBJECTIVE : To investigate the protective effects of
natakalim against
rat aortic vascular endothelial cells ( RAVECs )
injuries induced by
hypoxia and its mechanisms . -
pubmed
HIV , hepatitis C , and most recently Chikengunya virus , and in the case of
HIV associated articular manifestations , the introduction of HAART has resulted in a decrease in the incidence and development of newer complications such as the
immune reconstitution syndrome . -
pubmed
The
HPV test has similar sensitivity but more overdiagnosis than the Pap test -- a randomised health services study on
cervical cancer screening in Finland . -
pubmed
We compared test sensitivity ( in terms of prevented
cancers ) and overdiagnosis ( in terms of non - progressive pre - invasive lesions ) between the
human papillomavirus test (
HPV test , Hybrid Capture 2 ) and the traditional Pap test in routine screening for
cervical cancer . -
pubmed
Apoptosis in
human hepatoma HepG2 cells induced by
corn peptides and its anti -
tumor efficacy in
H22 tumor bearing
mice . -
pubmed
This study was aimed at evaluating the anti -
tumor mechanism of
corn peptides ( CPs ) . -
pubmed
Anatomical closure technique of the nasal floor for
patients with complete unilateral
cleft lip and palate . -
pubmed
We describe a new technique for the reconstruction of the nasal floor at the same time as cheiloplasty in
patients with complete
unilateral cleft lip and palate . -
pubmed
Three hundred and fifty - eight
patients have been treated using this technique , most of whom ( n = 233 , 65 % ) were boys , and 288 ( 80 % ) presented with a right complete
unilateral cleft . -
pubmed
The reductions in vertical
HIV transmission observed in Europe and North America have helped raise the possibility of the virtual elimination of new pediatric
HIV infections and in turn an "
AIDS - free generation " . -
pubmed
Immunoproteomic characterization of
Ambrosia artemisiifolia pollen allergens in canine
atopic dermatitis . -
pubmed
Canine
atopic dermatitis (
CAD ) is an
immune system disorder that affects 10 - 15 % of the
canine population . -
pubmed
Therefore , characterization of
Ambrosia artemisiifolia pollen components , in terms of defining major and minor allergens that induce clinically manifested
allergic reaction in
dogs , is important for valid diagnosis and efficient therapy . -
pubmed
This study has , for the first time , characterized and identified major
Ambrosia artemisiifolia allergens in
CAD , using an immunoproteomic approach . -
pubmed
BACKGROUND : The gene encoding c - fos is an important factor in the pathogenesis of
joint disease in
patients with
osteoarthritis . -
pubmed
This review focuses on the different features of the
metabolic syndrome and the influence of functional foods on these aspects , involving
dyslipidemia , improvement of
insulin sensitivity , serum lipid profile , antioxidant status , anti - inflammatory status and weight management of
humans . -
pubmed
With genetic , molecular , imaging and electrophysiological studies being supported by behavioural studies using
animal models , there is real hope that we may soon understand the fundamental pathology of
autism . -
pubmed
The Shank family of proteins has been strongly implicated as a contributing factor in
autism in certain
individuals and sits at the core of the alleged autistic pathway . -
pubmed
Brown adipose tissue thermogenesis contributes to
emotional hyperthermia in a resident
rat suddenly confronted with an intruder
rat . -
pubmed
In the present study we compared BAT , core body , and brain temperature , and tail blood flow , simultaneously measured , to determine whether BAT thermogenesis contributes to
emotional hyperthermia in a resident
Sprague - Dawley rat when an intruder
rat , either freely - moving or confined to a small cage , is suddenly introduced into the cage of the resident
rat for 30 min . -
pubmed
However , an improved understanding of the pathophysiology of
neuropathic pain and a growing number of adjuvant medications that are useful for the treatment of
neuropathic pain provide renewed hope for clinicians and their
patients . -
pubmed
We report on an infant
boy with
CNDI who showed
growth failure during treatment with
sodium restriction . -
pubmed
High - dose - rate brachytherapy for
vaginal rhabdomyosarcoma using a personalized mold in a 20 - month old
patient . -
pubmed
[ Molecular typing and surveillance on
Salmonella typhimurium strain in Guangdong province , 2009 - 2011 ] . -
pubmed
Clinical experiments examined nasal airway secretions obtained from
asthmatic children during naturally occurring rhinovirus - induced exacerbations ( n = 20 ) vs. non - asthmatic uninfected controls ( n = 20 ) . -
pubmed
Intrauterine exposure to
gestational diabetes mellitus (
GDM ) is linked to development of
hypertension ,
obesity , and
type 2 diabetes in
children . -
pubmed
Increased aortic stiffness predicts future development and progression of
peripheral neuropathy in
patients with
type 2 diabetes : the Rio de Janeiro Type 2 Diabetes Cohort Study . -
pubmed
We aimed to evaluate the predictors of the development and progression of
DPN in a cohort of high - risk
patients with
type 2 diabetes . -
pubmed
METHODS : In a prospective study , 477
patients with
type 2 diabetes were clinically assessed for the presence of
DPN at baseline and after a median follow - up of 6.2 years ( range 2 - 10 years ) . -
pubmed
RESULTS : At baseline , 135
patients ( 28 % ) had
DPN , and during follow - up 97
patients ( 20 % ) had either a new development or a worsening of
DPN . -
pubmed
Patients who showed a development or progression of
DPN were taller and had a longer duration of
diabetes , a greater prevalence of other
microvascular complications and
hypertension , greater aortic stiffness and poorer glycaemic control than
patients who did not have new or progressive
neuropathy . -
pubmed
After adjustments for the baseline prevalence of
DPN , the
patient 's age and sex , and the time interval between
DPN assessments ; an increased aortic stiffness ( cf - PWV & gt;10 m / s ) were predictive of new / progressive
DPN ( incidence rate ratio 2.04 , 95 % CI 1.28 , 3.23 ; p = 0.002 ) . -
pubmed
Taken together , the results show that lysosomal membrane permeabilization and
lysosomal dysfunction are triggered by AGEs , which induce autophagic inactivation in TECs from
patients with
DN . -
pubmed
Efficacy of acupuncture in
children with
asthma : a systematic review . -
pubmed
BACKGROUND : We performed a systematic review of the efficacy of various types of acupuncture in the treatment of
asthma in
children . -
pubmed
However , the results suggest that acupuncture may have a beneficial effect on PEF or PEF variability in
children with
asthma . -
pubmed
The methods were applied to eight microarray gene expression data sets , totaling 1324
patients with two clinical endpoints , overall survival and
relapse - free survival . -
pubmed
Here we report that an aversive experience in
mice , such as foot -
shock exposure ( FsE ) , induces LHb neuronal
hyperactivity and
depression - like symptoms . -
pubmed
In this article , the recent available information on W
toxicity in plants and
plant cells is reviewed , and the knowledge gaps and the most pertinent research directions are outlined . -
pubmed
In the endangered
Scottish chough (
Pyrrhocorax pyrrhocorax ) population , a
lethal blindness syndrome is found to be caused by a deleterious recessive allele . -
pubmed
( ) report on a strange , lethal ,
blindness that regularly affects
chicks of an endangered bird population . -
pubmed
Concomitant
aneurysm detection in an
intracranial dolichoectasia mouse model using a MicroFil polymer perfusion technique . -
pubmed
OBJECTIVE : To assess the feasibility of using MicroFil polymer perfusion to detect concomitant
saccular aneurysms in an
intracranial arterial dolichoectasia ( IADE ) model in
mice , and to report detailed histomorphometric features of these
aneurysms . -
pubmed
Fifteen concomitant
saccular aneurysms were detected in 8 ( 21 % ) of the 38 surviving
mice , including 6 at the posterior communicating artery , 1 along the ACA , 2 along the anterior communicating artery complex , 3 along the ICA , and 3 along the middle cerebral artery . -
pubmed
CONCLUSIONS : The proportion of subjects developing
saccular aneurysms in addition to IADE in our
mouse model is similar to the 15 % of
patients with IADE who have concomitant
saccular aneurysms . -
pubmed
Use of
dofetilide in adult
patients with
atrial arrhythmias and
congenital heart disease : A PACES collaborative study . -
pubmed
BACKGROUND :
Arrhythmia management has become the major treatment challenge in adult
patients with
congenital heart disease (
ACHD ) . -
pubmed
We included
patients ( age & gt;=18 years ) with
congenital heart disease who had
atrial fibrillation (
AF ) or
intra - atrial reentrant tachycardia treated with
dofetilide . -
pubmed
A total of 3 ( 4.7 % )
patients had major inpatient adverse events :
torsades de pointes ( n = 1 , 1.5 % ) ,
ventricular tachycardia ( n = 1 , 1.5 % ) , and corrected
QT prolongation requiring discontinuation ( n = 1 , 1.5 % ) . -
pubmed
Dofetilide was discontinued in 1
patient because of
sinus node dysfunction , and another
patient discontinued therapy before discharge because of persistent
arrhythmia . -
pubmed
OBJECTIVE : To carry out a retrospective study of the clinical features of
patients with intrauterine
hematoma in the second and third trimesters , and discuss the risk factors for poor pregnancy outcomes . -
pubmed
[ Establishment of
Human Chronic Lymphocytic Leukemia Model in the BALB / c Nude
Mice by Using
MEC-1 and
HG3 Cell Lines ] . -
pubmed
OBJECTIVE : To explore the the optimal condition for establishing
immune deficiency mouse(BALB / c ) model with
CLL via subcutaneous inoculation of
human chronic lymphocytic leukemia ( CLL ) cells at different inoculative locations and different cell concentrations . -
pubmed
Meanwhile , the
tumor - bearing
mice were killed , and the
tumors were isolated and cut into slices for histopathological examination . -
pubmed
In this study ,
rats were treated with
spermidine , an activator of autophagy , and injected with
sodium laurate via the internal carotid artery to stimulate
cerebral small vessel disease (
CSVD ) . -
pubmed
OBJECTIVES : Our aim was to analyze our experience with orthotopic liver transplant for
hepatoblastoma patients . -
pubmed
MATERIALS AND METHODS : We performed a single - center retrospective analysis of 6 orthotopic liver transplant cases in
children with
hepatoblastoma from 2001 to March 2015 . -
pubmed
Five
patients were free of
tumor recurrences at a median follow - up of 29.9 months . -
pubmed
This study aimed to determine whether
ticagrelor 60 mg twice daily ( bid ) provided potent and consistent platelet inhibition in
patients with vs without
diabetes in the PEGASUS - TIMI 54 platelet function substudy . -
pubmed
Out of 180
patients studied , 58
patients were randomised to and had received at least four weeks of
ticagrelor 60 mg bid , with 20 ( 34 % ) having
diabetes , 58
patients received
ticagrelor 90 mg bid , with 12 ( 21 % ) having
diabetes , and 64
patients received placebo , with 18 ( 28 % ) having
diabetes . -
pubmed
Patients with
diabetes did not have an increased incidence of high platelet reactivity in either
ticagrelor group . -
pubmed
Platelet reactivity was similar in
patients with
diabetes treated with
ticagrelor 60 mg vs 90 mg bid . -
pubmed
In conclusion ,
ticagrelor 60 mg bid is equally effective at reducing platelet reactivity in
patients with and without
diabetes , yielding a consistently high level of platelet inhibition regardless of
diabetes status . -
pubmed
In addition , the spheroids generated from different
human tumor cells exhibited distinct sensitivities toward drug chemotherapeutic agents and radiation as compared with two - dimensional ( 2D ) cultures that often lack in vivo - like biological insights . -
pubmed
Induction of
chronic cholestasis without
liver cirrhosis - Creation of an
animal model . -
pubmed
Evaluation of changes to the
Rickettsia rickettsii transcriptome during mammalian
infection . -
pubmed
The lifecycle of
Rickettsia rickettsii includes
infection of both mammalian and arthropod hosts , with each environment presenting distinct challenges to survival . -
pubmed
PATIENT SAMPLE : Thirty - one
subjects with
WAD and 31 age- and sex - matched controls were recruited from an ongoing randomized controlled trial . -
pubmed
Purpose : The purpose of this study was to determine the safety of topical ocular administration of a cross - linked , modified
hyaluronic acid (
xCMHA - S ) hydrogel , and its effectiveness in accelerating repair and closure of acute and nonhealing
corneal ulcers in companion animals as a veterinary treatment and its utility as a model for therapy in
human corneal ulceration . -
pubmed
Then , 30
dogs and 30
cats with spontaneous acute
corneal ulcers were treated with either xCMHA - S ( 0.75 % ) or a non - cross - linked
hyaluronic acid ( HA ) solution ( n = 15 per group for each species ) , three times daily until the
ulcer had healed . -
pubmed
Finally , 25
dogs with persistent nonhealing
corneal ulcers were treated with xCMHA - S ( 0.75 % ) twice daily until the
ulcer had healed . -
pubmed
Topically applied xCMHA - S significantly accelerated closure of acute
corneal stromal ulcers in
dogs and
cats compared with a non - cross - linked HA solution . -
pubmed
Further , topical administration of the
xCMHA - S aided in closure of nonhealing
corneal stromal ulcers in
dogs . -
pubmed
This study demonstrates that a cross - linked , modified HA hydrogel provides further benefit by accelerating time to corneal
wound closure compared to a non - cross - linked HA solution in companion animals , and therefore may be beneficial in fulfilling an unmet need in
humans . -
pubmed
The study involved 58
patients with
chronic noncalculous cholecystitis (
CNC ) divided into two groups . -
pubmed
A 55 - year - old morbidly obese
woman [
body mass index (
BMI ) 51.2 ] developed acute
type A aortic dissection , and she also presented with significant
hypoxemia and
hypercapnia . -
pubmed
Animals were sacrificed after 8 weeks of treatment by an
overdose of
sodium pentobarbital ( 160 mg / kg
body weight ) . -
pubmed
STZ60
animals presented with significantly lower
body weights compared to both control and STZ30 groups . -
pubmed
A recent study characterized the proteomic alterations induced by
Coxsackievirus type B ( CVB ) infection of
human islets . -
pubmed
Simultaneous Video - EEG - ECG Monitoring to Identify
Neurocardiac Dysfunction in
Mouse Models of
Epilepsy . -
pubmed
Electroencephalography ( EEG ) and electrocardiography ( ECG ) are widely used clinical diagnostic tools to monitor for
abnormal brain and cardiac rhythms in
patients . -
pubmed
Video - EEG - ECG monitoring in
mouse models of
epilepsy or other
neurological disease provides a powerful tool to identify dysfunction at the level of the brain , heart , or brain - heart interactions . -
pubmed
Subcutaneous
Ehrlich Ascites Carcinoma mice model for studying
cancer - induced
cardiomyopathy . -
pubmed
In this study , we establish a suitable model to study
breast cancer - induced
cardiomyopathy in
mice . -
pubmed
We used Ehrlich Ascites Carcinoma cells to induce
subcutaneous tumor in 129 / SvJ
mice and studied its effect on heart function . -
pubmed
In Ehrlich Ascites
Carcinoma bearing
mice , we found significant reduction in left ventricle wall thickness , ejection fraction , and fractional shortening increase in left ventricle internal diameter . -
pubmed
We found higher
muscle atrophy , degeneration ,
fibrosis , expression of cell - adhesion molecules and cell
death in
tumor - bearing
mice hearts . -
pubmed
We propose that Ehrlich Ascites
Carcinoma induced
tumor can be used as a model to identify potential therapeutic targets for the treatment of
heart failure in
patients suffering from
cancer - induced
cardiomyopathy . -
pubmed
METHODS : We conducted a longitudinal prospective study of
breast cancer patients on
tamoxifen ( n = 410 ) . -
pubmed
At each visit , blood samples were collected , and
patients completed a standardized
hot flash survey ( n = 1144 ) that reflected
hot flash severity during the 7 days prior to the visit . -
pubmed
Most
patients ( 92.2 % ) experienced
hot flash symptoms with 51.0 % having low HFSS ( 0 - 4 ) and 7.32 % experiencing HFSS & gt ; 25 . -
pubmed
Age was significantly associated with
hot flash severity , with
patients aged 45 - 59 more likely to have higher HFSS . -
pubmed
Human gammaherpesviruses are associated with
malignancies in
HIV infected individuals ; in macaques used in non -
human primate models of
HIV infection ,
gammaherpesvirus infections also occur . -
pubmed
We comprehensively examine all three - rhesus macaque gammaherpesviruses -
Rhesus rhadinovirus (
RRV ) , Rhesus Lymphocryptovirus (
RLCV ) and
Retroperitoneal Fibromatosis Herpesvirus (
RFHV ) in macaques experimentally infected with
Simian Immunodeficiency Virus or Simian
Human Immunodeficiency Virus ( SIV / SHIV ) in studies spanning 15 years at the
AIDS and Cancer Virus Program of the Frederick National Laboratory for
Cancer Research . -
pubmed
Local regressions showed that longitudinal VL patterns in cases and controls , from
SIV infection to necropsy , differed for each gammaherpesvirus : while
RFHV VL increased only slightly in all animals , RLCV and
RRV VL increased significantly and continued to increase steeply in cases ; in controls , VL flattened . -
pubmed
Moreover , the probe shows potent
phototoxicity to both Gram - negative bacteria (
Escherichia coli ) and Gram - positive bacteria (
Bacillus subtilis ) . -
pubmed
Ertugliflozin for treatment of
patients with
Type 2 diabetes mellitus . -
pubmed
Results : A total of 2 033 eligible
patients with complete information were screened from 2 224
type 2 diabetic patients . -
pubmed
METHODS : A total of 71
girls with
PA and 52 healthy
girls , as the control group , were recruited . -
pubmed
Similar findings were observed in response to
injury in
porcine vein grafts and stent models in vivo . -
pubmed
Favourable subgroups included
patients with lung
metastasis [ HROS 0.324 ( 95 % CI 0.146 - 0.717 ) , P = 0.008 ] and
disease - free interval of & gt;12 months [ HROS 0.307 ( 95 % CI 0.131 - 0.724 ) , P = 0.004 ] , but no difference was observed for metastatic burden . -
pubmed
NETs are an important first - line defense mechanism against
bacterial , viral , fungal , and
parasitic infections , but they can also play a role in
autoimmune diseases . -
pubmed
NETs are immunogenic and toxic structures that are recognized by the autoantibodies of
patients with
antineutrophil cytoplasmic antibodies - associated vasculitis (
AAV ) ( i.e. -
pubmed
We report the antenatal managing of a
patient in which
Goujerot - Sjogren disease was diagnosed after the revealing of an
atrioventricular block in her fetus . -
pubmed
The present study aimed to determine the factors associated with early
recurrence and
cancer death for
patients with
ESCC treated by trimodal therapy . -
pubmed
PATIENTS AND METHODS : We evaluated risk factors for
recurrence within 6 months , as well as
cancer death within 1 year based on data from 141
patients with
ESCC who underwent NCRT followed by curative esophagectomy . -
pubmed
Postoperative complications , ypT , ypN , poorer
tumor differentiation , lymphatic invasion and venous invasion were significant factors in a comparison of
patients with and without early
cancer death . -
pubmed
CONCLUSION : Further reduction of
postoperative complications are needed after NCRT for
patients with
ESCC . -
pubmed
Meticulous surveillance and postoperative adjuvant therapy should be considered for
patients with risk factors for early
recurrence and
cancer death . -
pubmed
Ninety - seven specimens of
tumor tissue and 77 adjacent
normal tissues from
patients with
breast cancer were examined . -
pubmed
All
patients underwent modified radical mastectomy or local
tumor resection without lymph node dissection . -
pubmed
Twenty - four chronic
stroke patients who underwent resting - state functional MRI and diffusion tensor image were retrospectively included . -
pubmed
All
patients were classified into two groups ( mild
motor impairment : 11
patients and severe
motor impairment : 13
patients ) according to their Fugl - Meyer motor assessment score . -
pubmed
METHODS : We conducted a cross - sectional study of Michigan - born preterm
infants utilizing dried blood
spots . -
pubmed
This study describes the use of an
animal model of
postmenopausal osteoporosis to generate a comprehensive dataset on miRNA regulation in bone tissue and peripheral blood during bone loss and specifically anti - resorptive and osteo - anabolic treatment . -
pubmed
Antimalarials such as
quinolines are crucial to fight against
malaria , but
malaria control is extremely challenged by the limited pipeline of effective pharmaceuticals against drug - resistant
strains of
Plasmodium falciparum which are resistant toward almost all currently accessible antimalarials . -
pubmed
In recent years , numerous of
quinoline hybrids were developed , and their activities against a panel of drug - resistant
P falciparum strains were screened . -
pubmed
The effect of
pilocarpine on
dental caries in
patients with primary
Sjogren ' s syndrome : a database prospective cohort study . -
pubmed
Pilocarpine , a salivary stimulant , can improve the amount and flow rate of saliva in
patients with
pSS . -
pubmed
RESULTS : A total of 4973
patients with new - onset
pSS were eligible for analysis . -
pubmed
CONCLUSION :
Pilocarpine may have no protective effect on
dental caries ,
periodontitis , or
oral candidiasis in
patients with
pSS . -
pubmed
It is still unclear how these pathological changes correlate with the development of
CJD symptoms because few
patients survive beyond 2 years after diagnosis . -
pubmed
Compared with traditional monolayer cell culture , the three - dimensional
tumor spheroid has emerged as an essential in vitro model for
cancer research due to the recapitulation of the architecture and physiology of solid
human tumors . -
pubmed
Patients who had a
chylothorax in group A had a significantly shorter postoperative hospital stay , less mean drainage volume per day , and less total drainage than those in group B ( 7.25 + - 0.50 days vs. 11.00 + - 2.81 days , p = 0.003 ; 0.64 + - 0.04 L vs. 0.80 + - 0.09 L , p = 0.003 ; 4.64 + - 0.40 L vs. 8.82 + - 2.84 L ; p = 0.002 ) . -
pubmed
Patients with
diabetic VH were identified in this retrospective study undertaken at King Khaled Eye Specialist Hospital , Riyadh , Saudi Arabia . -
pubmed
In brief , the findings of pyroptosis - dependent
cancer progression , new drugs and therapeutic target may lead to a promising , novel therapeutic approach for
cancer patients . -
pubmed
Streptococcus agalactiae Endocarditis and Melena . -
pubmed
Resveratrol improves lipid metabolism in
diabetic nephropathy rats . -
pubmed
RECENT FINDINGS : In new
human and
nonhuman primate (
NHP ) vaccine trials as well as studies of
natural infection , Fc - mediated effector responses have sometimes been observed to correlate with decreased risk of
infection or with better clinical outcomes , suggesting a potential role for these responses in
HIV-1 prevention and therapy . -
pubmed
A 50 - year - old
woman developed
gait disturbances and
dysarthria since the past 2 years . -
pubmed
Dystonia is relatively rare in
AxD patients , but this case demonstrated that
AxD should be listed in the differential diagnosis of
extrapyramidal syndromes with
abnormalities of the medulla and spinal cord on MRI . -
pubmed
The Fluid and Catheter Treatment Trial ( FACTT ) randomized
patients with
ARDS to conservative versus liberal fluid management strategies . -
pubmed
In a propensity score matched analysis , the difference in the effect of a conservative as compared to liberal fluid management strategy on ventilator free days was 2.23 days ( 95 % CI : -0.97 to 5.43 days ) in
diabetic patients , and 2.37 days ( 95 % CI : -0.21 to 4.95 days ) in non -
diabetic patients . -
pubmed
The difference in the effect of a conservative as compared to liberal fluid management on 60 day mortality was 2 % ( 95 % CI : -11.8 % to 15.8 % ) in
diabetic patients , and -7.9 % ( 95 % CI : -21.7 % to 5.9 % ) in non - diabetic patients . -
pubmed
The antalgic effects of
tiapride by IM route are evaluated in a randomized study on 30
patients with different kinds of
neoplasia - related
pain . -
pubmed
Imbalances of T cell subpopulations in
patients with
atopic diseases and effect of specific immunotherapy . -
pubmed
Immunotherapy of a
murine ovarian carcinoma with
Corynebacterium parvum and specific heteroantiserum . -
pubmed
injection of syngeneic
murine ovarian carcinoma ( MOT ) cells . -
pubmed
Activation of peritoneal cells to produce lysis of
tumor in the presence specific antiserum peaked 3 to 7 days after a single injection of
C. - pubmed
Of 15
patients with either
atrial fibrillation or both
left ventricular hypertrophy and an increased cardiace volume , six had pulmonary pressures elevated above normal values ; none of 14 patients with only one of the two signs (
left ventricular hypertrophy or increased cardiac volume ) had elevated pulmonary pressures . -
pubmed
Also , the 34
patients with normal roentgenologic and electrocardiographic findings had normal hemodynamics , irrespective of a history of previous
AMI , present
angina or
dyspnea on exertion . -
pubmed
It is concluded that hemodynamic studies by means of a balloon - tipped catheter floating in the pulmonary artery are indicated before major surgery in
patients with either
atrial fibrillation or both electrocardiographic and roentgenologic signs of
left ventricular hypertrophy . -
pubmed
[ Effect of
AS-4370 on gastric motility in
patients with
diabetic autonomic neuropathy ] . -
pubmed
Delayed gastric emptying in
diabetic patients occurs with progress of automatic
neuropathy as one late complication . -
pubmed
In this study , we evaluated the effect of
AS-4370 on gastric motility in
diabetic patients with
autonomic neuropathy . -
pubmed
Eight
diabetic patients with
autonomic neuropathy ( 3
males and 5
females ) with mean age of 56 years old ( range 29 - 66 ) participated to this study after giving written informed consent . -
pubmed
Patients showing
skin reaction during
mitomycin C vesical instillation should be patch tested to make a decision whether the drug might be continued ( toxic reaction ) or discontinued (
allergic reaction ) . -
pubmed
The latter are due either to the
HIV itself or to
opportunistic infections and
malignancies . -
pubmed
Between November 1980 and July 1989 , 29 ex vivo reconstructions were performed in 12 women and five
men ( mean age : 42 years ) for
dysplastic lesions of renal artery branches . -
pubmed
Fifteen
patients had
hypertension , associated with advanced
renal failure in one case . -
pubmed
Eleven of 15
hypertensive patients completely recovered while four were improved . -
pubmed
For
fibromuscular dysplasia occurring in young
patients whose life expectancy is usually long , this type of surgery provides excellent long - term clinical and anatomical results . -
pubmed
Emergence of drug - resistant
Mycobacterium tuberculosis in
HIV - infected patients . -
pubmed
Normalization of pressure - natriuresis by
nisoldipine in spontaneously
hypertensive rats . -
pubmed
This study examined whether the
calcium antagonist
nisoldipine can shift the relations between
sodium excretion , papillary blood flow , renal interstitial pressure , and renal perfusion pressure toward lower pressures in spontaneously
hypertensive rats . -
pubmed
Mean arterial pressure decreased similarly by 9 % and 12 % in Wistar - Kyoto and spontaneously
hypertensive rats after
nisoldipine ( 0.5 microgram / kg bolus + 0.017 microgram / kg / min ) . -
pubmed
In contrast , urine flow and
sodium excretion rose by 121 % and 132 % in spontaneously
hypertensive rats , and fractional
sodium excretion rose from 1.9 + /- 0.3 to 4.2 + /- 0.4 % . -
pubmed
Control
sodium excretion , papillary blood flow , and renal interstitial pressure were significantly lower in spontaneously
hypertensive rats than in
Wistar - Kyoto rats when compared at similar renal perfusion pressures . -
pubmed
Sodium excretion , papillary blood flow , and renal interstitial pressure all increased in spontaneously
hypertensive rats after
nisoldipine , whereas it had no effect on papillary blood flow or renal interstitial pressure in
Wistar - Kyoto rats . -
pubmed
The relations among
sodium excretion , papillary blood flow , renal interstitial pressure , and renal perfusion pressure were shifted toward lower pressures in spontaneously
hypertensive rats given
nisoldipine and became similar to those seen in
Wistar - Kyoto rats . -
pubmed
These results indicate that
nisoldipine normalizes the relations among
sodium excretion , renal interstitial pressure , papillary blood flow , and renal perfusion pressure in spontaneously
hypertensive rats perhaps by correcting the defect in renal medullary perfusion associated with resetting of pressure natriuresis in this model of
hypertension . -
pubmed
Masticatory function was examined in 17
patients with
mandibular prognathism before and after bilateral sagittal splitting osteotomy of the mandibular rami . -
pubmed
Concerning masticatory efficiency , mean values of absorbance of
ATP granules in
patients with
mandibular prognathism were inferior to those of subjects who possess a normal occlusion , even 12 months after operation . -
pubmed
The series comprised a total of 54
patients , 14 of whom complained of mild
dizziness or
nausea which did not require specific treatment . -
pubmed
Adrenergic influences on cardiac function during
ventricular fibrillation in isolated
rat hearts . -
pubmed
Effects of
norepinephrine ( NE , 10(-6 ) M ) ,
epinephrine ( E , 10(-6 ) M ) , and vehicle on coronary blood flow ( CF ) ,
oxygen consumption , and
lactate release were compared in 32 isolated
rat hearts during 5 min of
ventricular fibrillation (
VF ) . -
pubmed
A biochemical study of acute
ischemia in
rodent skin free flaps with and without prior elevation . -
pubmed
Rat epigastric flaps , with or without prior elevation , had 10 or 12 hours of acute
ischemia . -
pubmed
On
sodium - dodecyl - sulphate /
polyacrylamide gel electrophoresis these proteins co - migrated with proteins immunoprecipitated using serum from
rats inoculated with FBJ - MuSV - transformed cells (
tumour - bearing
rat serum ) . -
pubmed
In a randomized , double - masked study , 41
patients with
primary open - angle glaucoma or
ocular hypertension were treated with
betaxolol 0.5 % or
timolol 0.5 % drops for 26 weeks . -
pubmed
Two to three hours after the administration
patients became
psychotic again . -
pubmed
Moreover , the
beta - carboline norharman was present in blood obtained during acute
psychotic episodes and was not present in blood of nonsymptomatic
patients nor in blood of healthy controls . -
pubmed
A 54 - year - old nonasthmatic
man was found to have
allergic granulomatosis and
angiitis (
AGA ) (
Churg - Strauss syndrome ) with
pulmonary lesions suggestive of
diffuse panbronchiolitis (
DPB ) at autopsy . -
pubmed
Proposed mechanism of inheritance and expression of the
human fragile - X syndrome of
mental retardation . -
pubmed
A mechanism is proposed for the inheritance and expression of the
fragile - X - linked syndrome of
mental retardation in
humans . -
pubmed
Excellent results were obtained in two
patients with unilateral inveterate
dislocation of the mandible operated upon using this procedure . -
pubmed
[
Castor bean poisoning ] . -
pubmed
Isolation and characterization of an echovirus , possible " prime "
strain of
echovirus type 12 . -
pubmed
Metabolism and concentration of androgenic
steroids in abdominal skin of hirsute
women with
androgenital syndrome . -
pubmed
An in vitro study has been made of the
steroid metabolism in the abdominal skin in two hirsute
women with
adrenogenital syndrome , and the concentrations of the various
steroids in the skin tissue have been determined . -
pubmed
The extents of
steroid accumulation compared to the serum level in the same
patient were pathologically high in the case of
delta 5 - diol ,
DHT and
DHA - S in the abdominal skin of the two hirsute
women with
adrenogenital syndrome . -
pubmed
This confirmed that a state of
hyperandrogenism does exist in the skin of these
patients . -
pubmed
The absorption of effervescent
paracetamol ( 1000 mg ) was investigated in nine female
patients during a
migraine attack and in the same
patients when
headache free . -
pubmed
A comparison of micropuncture and
lithium clearance methods in the assessment of renal tubular function in
rats with
diabetes insipidus . -
pubmed
In the present study , fluid delivery from proximal tubules was estimated simultaneously by micropuncture and
lithium clearance techniques in anaesthetized
Brattleboro rats with
diabetes insipidus , under control conditions and following chronic treatment with
hydrochlorothiazide . -
pubmed
Pharmacokinetics and metabolism of a new hypnotic ,
zopiclone ( ZD ) , were studied under the following conditions : ( 1 )
rats and
dogs were given oral doses of the molecule ,
14C - labeled either on the side chain or on the
pyrrolopyrazine nucleus ; ( 2 )
rats ,
rabbits and
dogs were given increasing oral doses of the cold compound ; ( 3 )
human subjects in various physiopathological situations -- young and elderly healthy
volunteers ,
patients with
liver or renal impairments , nursing
mothers -- were given single or repeated doses , p.o . -
pubmed
In
human volunteers , plasma half - life of ZD increases with age , while
patients with
liver or renal impairments show little or no modification of pharmacokinetic parameters . -
pubmed
Comments on " Transcapillary water and protein flux in the
canine intestine with acute and
chronic extrahepatic portal hypertension " . -
pubmed
Mycoplasma - virus contacts , budding and
scars remaining in the membranes of
Acholeplasma laidlawii and its virus . -
pubmed
All
patients with false - positive results by radionuclide angiography had
cardiomyopathies , thus this test has a high specificity for
left ventricular dysfunction rather than for
CAD alone . -
pubmed
Criteria developed from the analysis of the test results in the 45 patients with definite diagnoses were then applied to the evaluation of 26 additional
patients with atypical
chest pain . -
pubmed
Based on this study a new approach for the noninvasive evaluation of
patients with suspected
coronary artery disease is proposed . -
pubmed
A total of 98
patients selected and classified into type IIa and IIb
hyperlipoproteinemia according to Fredrickson and Lees ( 1965 ) were pre - treated for 6 months with a commercially available combination product ( containing
clofibrate and
nicotinic acid ) . -
pubmed
Detection of
poliovirus antibodies and
poliovirus genome in patients with the
post - polio syndrome . -
pubmed
To investigate the role of
poliovirus ( PV ) infection in the development of the
post - polio syndrome (
PPS ) , we studied the serum , spinal fluid , peripheral blood lymphocytes , and muscle from 47
patients with
PPS . -
pubmed
The authors examined 21
outpatients with
obsessive - compulsive disorder for five neurological soft signs and abnormalities on two neuropsychological tests before and after 10 to 12 weeks of treatment with
serotonin reuptake inhibitors . -
pubmed
The
thymic lesion of the
nude mouse causes a profound block in T cell development . -
pubmed
Substantial palliation can be offered to the
patient with metastatic
carcinoid tumour , but the long - term outlook for these
patients remains poor . -
pubmed
The
patient prognosis for a small bowel
sarcoma is largely dependent on the
tumour grade . -
pubmed
A high index of suspicion to improve
tumour detection and better treatments of
tumours with the same histology at other anatomic sites should enhance the management and outcome of
patients with small
intestinal malignancies . -
pubmed
Comparison of bacterial culture results in bronchoalveolar lavage and nasal lavage fluid in
children with
pulmonary infection . -
pubmed
It aimed to study the relevance of bacterial culture results from nasal lavage fluid as compared with bronchoalveolar lavage fluid in
children with
pulmonary infection . -
pubmed
Purulent nasal secretions were observed in 9 out of 10
children presenting with acute unilateral
pneumonia within 1 - 2 days and who had not been treated with antibiotics ( Group 1 ) , and in 10 out of 15 children who had been ill for about 1 - 3 weeks and had not improved , even though antibiotic therapy had been instituted ( Group 2 ) . -
pubmed
Treatment with
isoniazid and
rifampicin for 9 months is adequate for
patients with localized
pleuropulmonary disease . -
pubmed
Necrosis and apoptosis associated with distinct
Ca2 + response patterns in target cells attacked by
human natural killer cells . -
pubmed
Human NK cells were found to be capable of inducing
necrosis ( membrane damage ) or apoptosis ( nuclear damage ) depending on the target cell types . -
pubmed
Bone marrow biopsy in 50
AIDS patients : a diagnostic approach . -
pubmed
It results that bone marrow morphologic examination in
HIV - positive patients plays a distinctive role in ruling out the presence of
opportunistic infections or associated
neoplasias ( haematologic or not ) and in contributing to clarify the significance of a
peripheral pancytopenia . -
pubmed
pseudomallei can grow and survive in an acidic environment , we suggest multifactorial mechanisms for the pathogenesis of
melioidosis due to
B. - pubmed
Genotypic and phenotypic virulence markers of the different categories of diarrheagenic
Escherichia coli were investigated in 76
strains of the enteropathogenic
E. - pubmed
Although its
mutagenicity has not been confirmed in
mouse germ cells ,
urethane (
ethyl carbamate ) gas induces a significant increase of X - linked recessive lethal mutations in the germ cells of
Drosophila melanogaster . -
pubmed
Seventy - four
patients from a prospective randomized trial comparing autologous bone marrow ( ABM ) versus blood stem cell ( BSC ) transplantation after high - dose chemotherapy for intermediate and high grade
non - Hodgkin ' s lymphoma (
NHL ) were studied for the presence of residual
lymphoma prior to transplantation . -
pubmed
The technique can be applied safely and effectively for therapy of common
tumors in
humans . -
pubmed
In the current study five
patients were treated by interstitial laser palliation with the
Nd : YAG laser using special fiberoptic applicator tips , which distribute laser energy efficiently throughout the
tumor volume . -
pubmed
Two
patients were diagnosed with
adenoid cystic carcinoma of the paranasal sinuses , one with a recurrent
carcinoma of the tongue and oropharynx , one with a recurrent
carcinoma limited to the oropharynx , and one
patient with a
carcinoma of the epi- and oropharynx . -
pubmed
The maximum follow - up without
recurrence was 2 years in a
patient with an
adenoid cystic carcinoma tumor of the paranasal
sinuses . -
pubmed
OBJECTIVE : To characterise
cardiac arrhythmias and cardiac autonomic function in 11 elderly
men ( mean ( SD ) age 73.2 ( 2.8 ) years ) with a lifelong history of regular very strenuous , exercise . -
pubmed
RESULTS : Nine of 11
athletes had complex
ventricular arrhythmias compared with five of 12 controls . -
pubmed
This method , using the appropriate rate constant , permits the determination of
tumor 10B concentration and is widely suitable for clinical BNCT , because the averaged PET data are enough to use in future
patients without individual PET study . -
pubmed
After oral administration to
rats ( 60 mg / kg ) fourteen compounds significantly inhibited the formation of
thrombi in arterioles and venules . -
pubmed
Pathological angiogenesis in a
murine model of
human Wilms ' tumor . -
pubmed
METHODS :
Human Wilms ' tumors were established in the right kidneys of
nude mice . -
pubmed
Effect of acute
hypoxia and
hypoxic acclimation on hemorheological behavior in
rats with
frostbite . -
pubmed
It was found that
cold injury in
rats acclimated to
hypoxia was more serious than that in nonacclimated ones . -
pubmed
In order to go further into the cause , blood rheological parameters in
rats of
frostbite at normoxia ( FN ) ,
frostbite during acute
hypoxia (
FAH ) and
frostbite during
hypoxia after hypoxic acclimation ( FHAC ) groups were observed before and after freezing . -
pubmed
The results suggest that the hemorheological behavior is deteriorated in
rats acclimated to
hypoxia or subjected to freezing , and worsens in hypoxic acclimation
rats after freezing . -
pubmed
The changes in hemorheological behavior may be one of the causes that would make the
frostbite damage more severe in
rats acclimated to
hypoxia . -
pubmed
In two
rat strains that are frequently used in behavioural analysis , i.e. -
pubmed
The results indicate that , although different
rat strains provide different baseline levels of behaviour for testing lesion- or drug - induced behavioural changes , lesions of the medial prefrontal cortex do not only disrupt sustained attention processes , but also induce a strong impairment in response inhibition in both Wistar and Lister
rats . -
pubmed
STUDY DESIGN : A
patient with
myxoid liposarcoma in the lumbar epidural space is reported . -
pubmed
METHODS : The authors have treated a female
patient with
myxoid liposarcoma in lumbar extradural space with marginal resection and posterior instrumentation . -
pubmed
These
patients had evidence of numerous posterior and peripheral
retinal lesions predating or occurring simultaneously with macular involvement . -
pubmed
Angiography may be reserved for
patients with a proven lesion or rapid
neurological deterioration taking into account the possibility of interventional treatment . -
pubmed
Underuse of inhaled
steroid therapy in elderly
patients with
asthma . -
pubmed
Multifocal
cystic lesions induced by
N - nitroso - bis ( 2 - hydroxypropyl ) amine in the
hamster exocrine pancreas . -
pubmed
They were found to consist mainly of cells that closely resembled those of
hamster pancreatic adenomas and
adenocarcinomas , confirming their status as precursors of these
tumors . -
pubmed
A 69 - year - old
woman who had had
lambda - type primary macroglobulinemia (
PMG ) since December 1993 was admitted in October 1997 because of
obstructive jaundice due to
compression of the common bile duct by a
retroperitoneal tumor . -
pubmed
Monitoring of atrial signals improves the accuracy in identifying
supraventricular tachyarrhythmias to prevent inappropriate therapies in
patients with implantable ICDs . -
pubmed
Defibrillation was successful with a 20 - J
shock in all
patients . -
pubmed
We report a 60 - year - old right - handed Japanese
man who showed an isolated persistent typing impairment without
aphasia ,
agraphia ,
apraxia or any other
neuropsychological deficit . -
pubmed
In the present study , we examined the frequency of diagnostic comorbidity in psychiatric
outpatients presenting for treatment of nonbipolar
major depressive disorder (
MDD ) and patients ' desire for treatment for the comorbid disorders . -
pubmed
PATIENTS : Twenty - three postoperative
patients with severe
sepsis and 26
patients with uneventful postoperative course as well as 24 healthy , age - matched subjects . -
pubmed
144 Turkish
children with
acute lymphoblastic leukemia (
ALL ) and 33 with
acute nonlymphoblastic leukemia (
ANLL ) were studied and compared with 185 healthy pediatric controls . -
pubmed
The number of each cell subset was compared between
patients and controls , as well as between groups of
patients stratified according to Breslow thickness of the primary
tumor ( & lt ; or = 2 mm vs & gt ; 2 mm ) or to survival after 3 years . -
pubmed
Autologous
tumor - cell vaccination has no contraindications or side - effects , since the
patients own materials ( lymphocytes ,
tumor cells ) are used . -
pubmed
Cancer cells may be obtained from tissue biopsies or biological fluids , or from long - term cultures from the
patient who is to be vaccinated . -
pubmed
Attempts to induce formation of
Rous sarcoma virus in cells of
tumour XC . -
pubmed
Sildenafil was examined in two
guinea pig models of
airways disease :
guinea pigs exposed to LPS or sensitized
guinea pigs with
atopy exposed to ovalbumen . -
pubmed
Intrinsic regulation of the heart in
teleosts is partly driven by central venous pressure , which exerts a modulatory role on
stroke volume according to the well - known Frank - Starling mechanism . -
pubmed
[
Typhoid meningoencephalitis of the
guinea pig from intracranial administration of endotoxin and its histologic characteristics ] . -
pubmed
BACKGROUND :
Human immunodeficiency virus (
HIV ) research involves ongoing , repetitious sequencing of the
HIV genome and the massive accumulation of associated investigational data . -
pubmed
A 61 - year old female
patient with
cutaneous sarcoidosis was treated with
fumaric acid esters (
Fumaderm ) . -
pubmed
[ Effect of
urinary tract infections in
children with
chronic renal failure on peritoneal dialysis ] . -
pubmed
UNLABELLED :
Urinary tract infections (
UTI ) in
children on dialysis treatment are regarded as indirect contraindication for kidney transplantation . -
pubmed
Total number of 57 culture - positive
UTI episodes were recorded ( 30 in
girls , 27 in
boys)--1 - episode/11.1 patient - month . -
pubmed
In examined group
UTI most frequently were present in children with uncorrected
urinary tract malformation ( 1 episode/7.7 patient - month ) and in
children on immunosuppressive treatment ( 1 episode/5.7 patient - month ) . -
pubmed
In
children with
cystic kidney disease infections had accidental character . -
pubmed
CONCLUSIONS : The most frequent occurring pathogen was bacteria
Escherichia coli--13 ( 22.8 % ) and
Streptococcus faecalis--13 ( 22.8 % )
infections . -
pubmed
Streptococcus faecalis strains revealed only partial sensitivity to
nitrofurantoin ,
vancomycin ,
teicoplanin . -
pubmed
METHODS : Serial samples of the airway aspirates ( AA ) were obtained during mechanical ventilation from 21 preterm
infants with
RDS , of which 12 were survivors (
birth weight 1.48 + /- 0.32 kg and gestational age 31 + /- 1.5 weeks ) and 9 nonsurvivors ( 1.34 + /- 0.31 kg and 30 + /- 2 weeks ) . -
pubmed
Urinary
calculi form from
urate ( salts of
uric acid ) and can cause
urethral obstruction in
male Dalmatians . -
pubmed
We postulated that
calculi formation might have a genetic component that segregates within the breed , causing some
animals to form
calculi and others to never form
calculi despite excreting
uric acid in their urine . -
pubmed
We used a survey to ascertain the
urinary calculi status based on clinical signs of adult Dalmatians aged 6 years or older , and we used pedigrees from these same
animals to estimate the heritability of the clinical manifestation of
urate calculi within the breed to be .87 ( .75-.96 ) . -
pubmed
PATIENTS AND METHODS : A total of 22 male
patients with a mean age of 52.9 years ( range 37 - 67 years ) were treated with SWL for distal
ureteral calculi close to the ureteral orifice . -
pubmed
None of the
patients had
urinary tract infection or any abnormal finding on digital rectal examination . -
pubmed
At 1 year , all
patients completed a questionnaire concerning recent diagnosis of
prostate cancer . -
pubmed
None of the
patients reported
prostate cancer at 1 year . -
pubmed
Pathologic quiz case :
giant mediastinal mass in a 69 - year - old
man . -
pubmed
A clear understanding of the different aspects of the procedure , including the risks and benefits of the treatment , assists neuroscience nurses in communicating with the
PD patient , and providing the most appropriate , knowledge - based pre- and postoperative care . -
pubmed
Survey of
zona pellucida antigens for immunocontraception of
cats . -
pubmed
[ Effects of
panax notoginseng saponins on the process of renal interstitial
fibrosis after unilateral
ureteral obstruction in
rats ] . -
pubmed
OBJECTIVE : To evaluate the effects of
panax notoginseng saponins ( PNS ) on the process of renal interstitial
fibrosis after unilateral
ureteral obstruction in
rats . -
pubmed
The unilateral ureters of the
rats were ligated as the operation to create renal interstitium
fibrosis . -
pubmed
RESULTS : After operation , the operated
rats showed progressive renal interstitium
fibrosis . -
pubmed
CONCLUSION : The lesions of tubules - interstitium got worse and the renal interstitium showed progressive
fibrosis gradually in
rats with unilateral
ureteral obstruction . -
pubmed
We report the case of a 31 - year - old
man who was diagnosed with
dermatomyositis . -
pubmed
Physical examination revealed an induration ( 2 cm x 2 cm ) in the left testis and the
patient was diagnosed with stage IIIB left
testicular cancer . -
pubmed
This case illustrates the importance of palpation of the testes in young
patients with
dermatomyositis . -
pubmed
RATIONALE : Nearly 100 years have passed since the first surgical attempt to remove a
craniopharyngioma was undertaken , and the management of
patients with these
tumors continues to both challenge and frustrate those involved with their treatment . -
pubmed
CONCLUSION : The application of radiotherapeutic techniques to the management of
craniopharyngioma would begin to complement the role of surgery , but debate would soon emerge as to what constituted the most appropriate management for
craniopharyngioma in
children . -
pubmed
BACKGROUND : Previous studies have drawn attention to the high postoperative mortality and poor survival of
patients who present as an emergency with
colon cancer . -
pubmed
METHODS : The study included 2068
patients who presented with
colon cancer between 1991 and 1994 in Scotland . -
pubmed
RESULTS : Thirty - day postoperative mortality following potentially curative resection was consistently higher in
patients who presented with evidence of
blood loss , obstruction or
perforation ( all P & lt ; 0.005 ) than in elective
patients . -
pubmed
The corresponding adjusted hazard ratios ( 95 per cent confidence interval ) for
cancer - specific survival , relative to elective
patients , were 1.62 ( 1.22 to 2.15 ) , 2.22 ( 1.78 to 2.75 ) and 2.93 ( 1.82 to 4.70 ) for patients presenting with evidence of
blood loss , obstruction or
perforation ( all P & lt ; 0.001 ) . -
pubmed
Treatment of
cytomegalovirus retinitis in
AIDS patients with intravitreal
ganciclovir . -
pubmed
BACKGROUND :
Cytomegalovirus ( CMV ) retinitis is the most common
opportunistic ocular infection in
AIDS patients , and frequently leads to
blindness if untreated . -
pubmed
MATERIAL AND METHOD : The participants were 363 consecutive
patients with
CMV retinitis treated at the
CMV Retinitis Clinic , Maharaj Nakorn Chiang Mai Hospital over the period from June 2001 to December 2003 . -
pubmed
CONCLUSION : Intravitreal
ganciclovir appeared to be a worthwhile therapeutic alternative for
CMV retinitis patients with unaffordable or intolerant to systemic anti -
CMV therapy , but the complications of intravitreal injections should also be recognized . -
pubmed
Critical time window for intra - arrest cooling with cold saline
flush in a
dog model of cardiopulmonary resuscitation . -
pubmed
BACKGROUND : Mild
hypothermia improves outcome when induced after
cardiac arrest in
humans . -
pubmed
Recent studies in both
dogs and
mice suggest that induction of mild
hypothermia during cardiopulmonary resuscitation ( CPR ) greatly enhances its efficacy . -
pubmed
METHODS AND RESULTS : Seventeen
dogs had
ventricular fibrillation cardiac arrest no flow of 3 minutes , followed by 7 minutes of CPR basic life support and 50 minutes of advanced life support . -
pubmed
In the early
hypothermia group , 7 of 9
dogs survived to 96 hours , 5 with good neurological outcome . -
pubmed
In contrast , 7 of 8
dogs in the delayed
hypothermia group died within 37 hours with
multiple organ failure ( P=0.012 ) . -
pubmed
Surgical treatment of
overgrowth of the greater trochanter in
children and adolescents . -
pubmed
Forty - four
patients with
trochanter overgrowth ( 47 hips ) ages 6 to 17 years underwent surgery . -
pubmed
OBJECTIVE : To identify Actinobacillus spp isolates recovered from fetuses and pericardial fluid from
horses affected with
mare reproductive loss syndrome (
MRLS ) and determine whether these bacterial species are the same as those isolated from clinically normal
horses . -
pubmed
Of the 18 isolates from horses with
pericarditis , 4 were
A equuli subsp equuli , 13 were
A equuli subsp haemolyticus , and 1 was Bisgaard taxon 10 - like bacterium . -
pubmed
CONCLUSIONS AND CLINICAL RELEVANCE : Actinobacillus spp isolates recovered from fetuses and pericardial fluid samples of
horses affected by
MRLS in 2001 to 2003 were identical to
Actinobacillus spp found in the oral cavity and alimentary tracts of healthy
horses . -
pubmed
One week of weathering increased the accumulation of
oxyradicals to almost 2 - fold and triggered the deteriorative cascade , by enhancing the lipid peroxidation and membrane perturbation , leading to cell
death in seed tissues and poor germinability and vigour of
soybean seeds . -
pubmed
Results of one - year anticoagulation in
patients with newly detected
chronic thromboembolic pulmonary hypertension not treated with pulmonary endarterectomy . -
pubmed
INTRODUCTION : Currently pulmonary endarterectomy is considered the method of choice in
patients with
chronic thromboembolic pulmonary hypertension (
CTEPH ) . -
pubmed
There is also doubt about selection of adequate time to refer
patients with
CTEPH for surgery . -
pubmed
METHODS : The prospective analysis involved 29
patients ( 9
male , 20
female ) aged 37 to 82 years , with pulmonary arterial
systolic pressure ranging from 39 to 133 mmHg and newly diagnosed
CTEPH who had not been treated with pulmonary endarterectomy and were not receiving anticoagulation . -
pubmed
CONCLUSIONS : The results of this study suggest that favourable effects of isolated anticoagulation are likely in
patients with newly detected
CTEPH , mild and moderate baseline
pulmonary hypertension and acceptable exercise tolerance . -
pubmed
Prediction of remission as a combination of symptomatic and functional remission and adequate subjective well - being in 2960
patients with
schizophrenia . -
pubmed
Complete remission required that
patients achieved symptomatic remission mirroring the Remission in
Schizophrenia Working Group criteria , functional remission , and a level of adequate subjective well - being over at least 6 months . -
pubmed
CONCLUSIONS : Despite advances in pharmacologic and psychosocial treatments in
schizophrenia , close to 90 % of the
patients in this study did not fulfill the combined remission criteria . -
pubmed
The finding that the course of the disorder depends on early outcome not only in previously untreated but also in more
chronically ill patients points toward a critical " window of opportunity " in the course of treatment . -
pubmed
OBJECTIVES : To determine the incidence of
ventilator - associated pneumonia (
VAP ) among intensive care unit ( ICU ) patients in Japan and to assess the impact of VAP on
patient outcomes , including mortality , length of stay , and duration of mechanical ventilation . -
pubmed
The standardized mortality rates for the
patients with
VAP was 1.3 ( 95 % confidence interval [ CI ] , 1.1 - 1.6 ): 1.1 ( 95 % CI , 0.9 - 1.4 ) for the cases due to drug - susceptible pathogens and 1.5 ( 95 % CI , 1.1 - 1.9 ) for the cases due to drug - resistant pathogens . -
pubmed
The potential impact of VAP on
patient outcomes emphasizes the importance of preventive measures against
VAP , especially for
VAP caused by drug - resistant pathogens . -
pubmed
METHODS : Ten
patients with
RVT were analyzed retrospectively . -
pubmed
RESULTS : Ten kidneys in nine
patients were confirmed to have
thrombus within the main renal veins , and one patient was confirmed to have
thrombus within the small intrarenal veins . -
pubmed
MATERIALS AND METHODS : We isolated stromal cells from
human squamous cell carcinoma tissue and studied their effect on phenotypic characteristics of normal
human interfollicular keratinocytes in vitro . -
pubmed
CONCLUSION : The association between
caffeine intake and risk of
PD was similarly observed in both fast and slow
caffeine metabolizers , supporting experimental evidence in
animal models that both
caffeine and its major metabolite ,
paraxanthine , are neuroprotective . -
pubmed
This double - blind controlled trial included 58
patients with chronic
traumatic ulcers . -
pubmed
METHODS AND MATERIALS : We analyzed
patients treated at the University of Texas Medical Branch between May 2002 and February 2006 who met the following criteria : ( 1 ) definitive IMRT without chemotherapy for
oropharyngeal SCC ; ( 2 ) no pretreatment radical surgery ; ( 3 ) minimal follow - up of 1 year . -
pubmed
A 90 - day
toxicity study of
L - asparagine , a food additive , in
F344 rats . -
pubmed
The present 90 - day
toxicity study in
F344 / DuCrlCrj rats was conducted for safety assessment and to determine a no observed adverse effect level ( NOAEL ) of
L - asparagine . -
pubmed
The NOAEL was determined to be 2.5 % in the diet (
males , 1.65 g / kg
body weight / day ; females , 1.73 g / kg
body weight / day ) . -
pubmed
PURPOSE : We aimed to describe computed tomography ( CT ) findings in
patients with
peritoneal , omental and mesenteric lymphoma involvement . -
pubmed
MATERIALS AND METHODS : We searched our archive retrospectively to find out
patients with
peritoneal , omental and mesenteric lymphoma involvement . -
pubmed
We found 16
patients with
non - Hodgkin lymphoma meeting these criteria . -
pubmed
CT studies of these
patients were reevaluated for the presence of peritoneal involvement ,
ascites ,
omental mass ,
organomegaly ,
retroperitoneal lymphadenopathy , bowel wall thickening and other associated findings . -
pubmed
RESULTS : There were 14
males and 2
females with peritoneal and/or mesenteric and omental
lymphoma involvement . -
pubmed
Ascites was seen in 12 ( 75 % )
patients . -
pubmed
Bowel wall thickening , retroperitoneal
lymphadenopathy and
hepatosplenomegaly were also common and observed in 10 , 10 and 11
patients , respectively . -
pubmed
Solid organ involvement in the form of
liver and splenic lesions was seen in 9 ( 56 % )
patients . -
pubmed
MATERIALS AND METHODS : Ninety - two consecutive
patients with
cirrhosis underwent three - phase CT and endoscopy . -
pubmed
RESULTS : Nine patients of 92
patients with
cirrhosis were excluded because of previous procedure or motion artifact ; the remaining 83
patients with
cirrhosis were evaluated . -
pubmed
In the
cirrhosis group , 40 ( 48.1 % ) of 83
patients showed the transient gastric perfusion defect sign . -
pubmed
In the cirrhotic group , the frequency of the transient gastric perfusion defect sign was significantly higher in the
patients with
PHG ( 75 % , 36/48 ) than in patients without
PHG ( 11.4 % , 4/35 ) . -
pubmed
CONCLUSION : The transient gastric perfusion defect sign could be used as a relatively specific sign of PHG in
patients with
cirrhosis . -
pubmed
The potential of the
nematode Caenorhabditis elegans , the
fruitfly ,
Drosophila melanogaster and the
zebrafish ,
Danio rerio , as model genetic
organisms for the study of
human muscle disease is discussed by examining their muscle biology , muscle genetics and development . -
pubmed
It is concluded that these
organisms have already demonstrated potential in facilitating the study of
muscle disease and in screening for therapeutic agents . -
pubmed
Retrospective comparative study of 80 consecutive
patients treated with either anterior cervical discectomy fusion ( ACDF ) or anterior cervical corpectomy fusion ( ACCF ) for multi - level
cervical spondylosis . -
pubmed
We evaluated 80 consecutive
patients who underwent surgery for the treatment of multi - level
cervical spondylosis at our institution from 1998 to 2001 . -
pubmed
There was one
patient in Group 1 and 2
patients in Group 2 with
pseudarthroses . -
pubmed
METHODS : This was a retrospective review of 204 emergency department pediatric
patients presenting between January 1 , 2005 and February 28 , 2006 with
appendicular trauma , with initially negative radiographic result and follow - up . -
pubmed
An estimated 750 million people are at risk of
infections with food - borne trematodes , which comprise liver flukes (
Clonorchis sinensis ,
Fasciola gigantica ,
Fasciola hepatica ,
Opisthorchis felineus , and
Opisthorchis viverrini ) , lung flukes ( Paragonimus spp . ) -
pubmed
Family - based randomized trial to detect effects on blood pressure of a salt substitute containing
potassium and
calcium in
hypertensive adolescents . -
pubmed
SETTING & amp ; PARTICIPANTS : 423
patients with
CKD ( stages 4 - 5 ) were randomly assigned between January 1999 and January 2003 and followed up until December 2006 or
death . -
pubmed
3
patients ( 0.7 % ) met criteria for
protein - caloric malnutrition . -
pubmed
Effect of virgin
olive oil plus
acetylsalicylic acid on brain slices damage after
hypoxia - reoxygenation in
rats with
type 1 - like diabetes mellitus . -
pubmed
Aspirin is the most widely used drug for the secondary prevention of
ischemic stroke in
patients suffering from
diabetes mellitus . -
pubmed
The aim of the present study was to determine the possible influence of VOO administration to
streptozotocin -
diabetic rats ( DR ) on the neuroprotective effect of
aspirin in
rat brain . -
pubmed
The main conclusion of our study is that daily oral administration of VOO to
diabetic rats may be a natural way to increase the neuroprotective effect of
aspirin in
diabetic animals . -
pubmed
Rabbit syndrome (
RS ) is an
involuntary movement disorder characterized by rapid , fine movements of an individual 's mouth , similar to the chewing movements of a
rabbit , and has most frequently been associated with the use of antipsychotic medications . -
pubmed
In particular , recent advances in the study on the earliest phase of
HIV-1 infection unearthed novel challenges for
HIV vaccine development . -
pubmed
The effect of antigens of
Bordetella pertussis and their antibodies on
brain infections by
B. - pubmed
Antisera to whole cell vaccines whether they contain the ; bactericidal antigen ' or not , or the protective antigen or not can more easily reduce
infections by mechanism ( 1 ) , eliminating small lethal challenges in some
mice which are protected . -
pubmed
Information about the effect of CCBs on incident
HF in
patients with
hypertension is scarce . -
pubmed
Trials of renal transplantation
patients , placebo - controlled trials , and
HF trials were excluded . -
pubmed
The analysis indicated a significant increase in the diagnosis of
HF in
patients allocated to CCBs ( odds ratio 1.18 , 95 % confidence interval 1.07 to 1.31 ) . -
pubmed
Furthermore , we observe that this defect is manifest early in
infection , as
M. - pubmed
Estivoautumnal (
Plasmodium falciparum )
malaria ; a survey of four hundred and ninety - three cases of
infection with Plasmodium falciparum in children . -
pubmed
Anterior uveal spindle cell tumor in a
cat . -
pubmed
PURPOSE : To describe a case of
anterior uveal spindle cell tumor in a
cat with features similar to
spindle cell tumor of blue eyed
dogs . -
pubmed
METHODS : A 10 - year - old female spayed domestic short - haired
cat was referred for an
iris mass OS . -
pubmed
The
cat was lost to follow - up for 2 years , after which time she re - presented with
glaucoma ,
blindness and grossly evident iridal mass enlargement
OS . -
pubmed
CONCLUSIONS : Based on its histopathologic characteristics , this
iris tumor was diagnosed as a Schwann cell variant of a
peripheral nerve sheath tumor (
PNST ) closely resembling the
spindle cell tumor of blue - eyed
dogs . -
pubmed
Anterior uveal PNST has not been previously reported in
cats to the authors ' knowledge . -
pubmed
Therefore , dietary
astaxanthin heightened cell - mediated and humoral immune response and reduced DNA damage and
inflammation in
dogs . -
pubmed
RESULTS : Twenty
patients ( 16
men ) with sinonasal
adenocarcinoma were found . -
pubmed
beta - arrestin deficiency protects against
pulmonary fibrosis in
mice and prevents fibroblast invasion of extracellular matrix . -
pubmed
MATERIALS AND METHODS : A total of 20 male
Wistar rats ( aged 3 months ) were divided into 2 groups : ( i ) control group fed with distilled water and ( ii ) experimental group fed with
TRF ( 200 mg/ kg
body weight ) for 8 months . -
pubmed
A survey of
ocular abnormalities in miniature
horses . -
pubmed
OBJECTIVE : To determine the incidence of
ocular abnormalities in miniature
horses . -
pubmed
One miniature
horse also had multiple
ocular abnormalities ( cornea globosa ,
goniosynechiae , decreased or absent and pupillary light reflexes , miotic and
dyscoric pupils ,
iris hypoplasia , and
epinuclear cataract ) . -
pubmed
Ocular abnormalities were observed in
horses that had a flaxen or white mane and tail color and a chocolate coat color . -
pubmed
CONCLUSIONS : Abnormal ocular phenotype detected in eyes of Miniature
Horses was similar to multiple
congenital and hereditary ocular abnormalities reported in the Rocky Mountain
Horse . -
pubmed
The authors highlight the unique contribution of the lymphatics to
wound healing , as well as the unique contribution of OMT to lymphatic - directed treatment of
patients with
chronic wounds . -
pubmed
The authors propose that this information be used as a basis for research into the effects of OMT on chronic
wound healing in
patients . -
pubmed
Claudication pain in the left arm of a coronary artery bypass graft
patient using crutches :
Coronary subclavian steal syndrome - a case report . -
pubmed
The pups were weaned for 21 days , and 6 weeks after the injection of
STZ , the
animals were checked for fasting
glucose level ( FPG ) & gt;=160 mg / dl were considered as
diabetic . -
pubmed
RESULTS : Significant and dose - dependent correction of postprandial and fasting
hyperglycemia was observed in
diabetic rats following 8 weeks of chronic therapy . -
pubmed
Dual
thienopyridine low - response to
clopidogrel and
prasugrel in a
patient with
STEMI ,
cardiogenic shock and early
stent thrombosis is overcome by
ticagrelor . -
pubmed
Little is known about the antiplatelet action of the
thienopyridines ,
clopidogrel and
prasugrel , as well as the non -
thienopyridine ,
ticagrelor , in
patients suffering from
ST - elevation myocardial infarction (
STEMI ) complicated by
cardiogenic shock since systematic comparisons of these antiplatelet agents in this devastating condition are limited so far . -
pubmed
This is a report of a
patient with
STEMI undergoing urgent PCI in
cardiogenic shock followed by repeated angioplasty after suffering early stent
thrombosis (
ST ) who showed dual
thienopyridine treatment failure of
clopidogrel and
prasugrel , which was successfully overcome by switching the
patient to the non -
thienopyridine derivative
ticagrelor . -
pubmed
UNLABELLED : A series of
nitroderivatives has been synthetized from natural and synthetic
olive oil
phenols to increase the assortment of compounds with a putative effect against
Parkinson disease . -
pubmed
Deficits in social behavior emerge during development after pediatric
traumatic brain injury in
mice . -
pubmed
The current study evaluated social behavior in
mice subjected to
TBI at post - natal day ( p)21 . -
pubmed
TBI mice also lacked a preference for social novelty , suggestive of a
deficit in social recognition or memory . -
pubmed
This emergence of
aberrant social behavior , which parallels the development of other
cognitive deficits in this model and behaviors seen in
brain - injured children , is consistent with the hypothesis that the full extent of deficits is not realized until the associated skills reach maturity . -
pubmed
BACKGROUND : Ramadan fasting for pregnant
women with
diabetes remains controversial and underreported . -
pubmed
METHODS : This was a retrospective study carried out over a period of three years including pregnant
diabetic women , who were on short - acting , intermediate - acting , or a combination of them , and opted to carry out Ramadan fasting . -
pubmed
These two markers were the best in detecting
patients with lymph node
metastases . -
pubmed
In conclusion , this comparative study established that p - proteasome quantification in combination with other
melanoma biomarkers is an attractive approach for the biological follow - up of
melanoma patients . -
pubmed
Apparent
mineralocorticoid excess syndrome : report of one family with three affected
children . -
pubmed
In
patients with
AME , this ratio is 5 - 18 , while in normal
individuals it is & lt;0.5 . -
pubmed
The finding of abnormally high ratios of 24 - h urine - free
cortisol to
cortisone in our three
patients ( case 1 , 8.4 ; case 2 , 25 ; and case 3 , 7.5 ) confirmed the diagnosis of
apparent mineralocorticoid excess syndrome in these
children . -
pubmed
A case of recurrent
labial adhesions in a 15 - month - old
child with asymptomatic non - classic
congenital adrenal hyperplasia due to
21 - hydroxylase deficiency . -
pubmed
This report presents the case of a 15 - month - old
girl with recurrent labial
adhesions and
urinary tract infections . -
pubmed
BACKGROUND : A role for
Epstein Barr virus (
EBV ) in
multiple sclerosis (
MS ) has been postulated . -
pubmed
PURPOSE : Postoperative
respiratory failure is a major problem which can prolong the stay in the intensive care unit in
patients undergoing cardiac surgery . -
pubmed
The
human vertebral body and intervertebral disc interface forms the region where the cartilaginous endplate , annulus
fibrosis and bone of the vertebral body are connected through an intermediate calcified cartilage layer . -
pubmed
The
hypercoagulability of
patients with
nephrotic syndrome could be an important trigger for arterial and venous
thrombotic events . -
pubmed
Here we report the case of a
patient with
stroke as first manifestation of
nephrotic syndrome . -
pubmed
: Of men , not
mice , and
inflammation . -
pubmed
PATIENTS AND METHODS : Thirty - six
patients with displaced
proximal humerus fractures from two centers were operated using locking plate . -
pubmed
In one of the 18 displaced proximal humerus
fractures of IMS ( + ) group , the head - shaft angle was measured to be & lt;125 , whereas six
patients had varus deviation in IMS ( - ) group at follow - up ( p & lt ; 0.05 ) . -
pubmed
A computed tomography scan of the
patient , who had sustained an impact
injury to the right occipital region , showed no
cerebral lesion . -
pubmed
Therefore , close ophthalmological and radiological evaluation is required in
patients with
TBI , in order to enable the diagnosis of
Terson syndrome and an early vitrectomy . -
pubmed
BACKGROUND :
Infection may trigger clinically overt
mucosal inflammation in
patients with predisposition for
inflammatory bowel disease . -
pubmed
MNV might thus trigger overt clinical disease in
individuals with a nonsymptomatic predisposition for
inflammatory bowel disease by
impairment of the intestinal mucosa . -
pubmed
Fifty - seven
patients of 58 studies confirmed the final diagnosis of
bowel obstruction by surgical proof or obstructive symptoms relief from conservative treatments ; divided into 25 small bowel and 33 large
bowel obstructions . -
pubmed
Granuloma malignum (
Hodgkin ' s disease ) in the
fin whale Balaenoptera physalus ) . -
pubmed
Thus , a determination of an effective
fluoride dentifrice may be beneficial in the reduction of the erosive process in
patients with
gastric disorders . -
pubmed
Efficacy of just - in - time
plerixafor rescue for
Hodgkin ' s lymphoma patients with poor peripheral blood stem cell mobilization . -
pubmed
Limited information is available on its use in
Hodgkin ' s lymphoma (
HL )
patients . -
pubmed
We describe our experience with
plerixafor as an immediate rescue agent in
HL patients with poor PBSC mobilization . -
pubmed
CONCLUSION :
Plerixafor can be used in
HL patients with poor mobilization as a rescue agent and boosts mobilization sufficiently in most
patients in the same collection attempt , thus not only permitting ASCT , but also avoiding remobilization and the associated costs , treatment delays , and
patient inconvenience . -
pubmed
Liver transplantation ( LT ) is the only curative treatment modality for
patients with
HPS . -
pubmed
This case report describes a
patient with typical findings of an extracardiac pulmonary arteriovenous shunt on contrast - enhanced transesophageal echocardiography ( TEE ) , and
clubbing fingers , who had complete correction of
HPS by deceased donor LT . -
pubmed
Mortality is three to four times higher in a
patient with
coagulopathy and thus prevention and correction of
coagulopathy is the central goal of the management of
hemorrhagic shock in
trauma . -
pubmed
Acetylcholine serves as a derepressor in
Loperamide - induced Opioid - Induced
Bowel Dysfunction (
OIBD ) in
zebrafish . -
pubmed
This 31 - year - old
woman presented with typical right
trigeminal neuralgia caused by a trigeminocerebellar artery , manifesting as
pain uncontrollable with medical treatment . -
pubmed
The
neuralgia resolved after the surgery ; the
patient had slight transient
hypesthesia , which fully resolved within the 1st month after surgery . -
pubmed
CONCLUSION :
Tobacco use caused one out of six
deaths in Casablanca in 2012 . -
pubmed
Early clinical improvement under antidepressant medication in the first 2 weeks of treatment is one of the best predictors for the long - term treatment outcome in
patients with major
depressive disorder . -
pubmed
In this study , lamellar morphology and pathology were described in 14
laminitic horses and
ponies that had
hyperinsulinemia ( & gt;20 mIU / l ) , with reference to 25 age- and breed - matched controls . -
pubmed
PARTICIPANTS : One hundred eight fellow untreated eyes of 143
patients with
GA resulting from
AMD enrolled in the MAHALO study ( clinicaltrials.gov identifier , NCT01229215 ) who completely satisfied the study term and had gradable spectral - domain optical coherence tomography ( OCT ) images obtained at both baseline and month 18 visits . -
pubmed
METHODS : The MAHALO study enrolled 143
subjects into a phase 1b/2 multicenter , randomized , single - masked , sham - injection controlled clinical trial of the safety , tolerability , and evidence of activity of lampalizumab in
patients with
GA associated with
AMD . -
pubmed
The present study reports our experience with five
renal cell carcinoma (
RCC )
patients with
brain metastases treated with
sunitinib and radiotherapy . -
pubmed
After treatment with
sunitinib , shrinkage of
brain metastases was achieved in all
patients with complete response , partial response and stable disease in two , one and two
patients , respectively . -
pubmed
Although progression of
brain metastases occurred in four of the five
patients , additional gamma - knife surgery was effective in three
patients . -
pubmed
The remaining one
patient died of
disease progression . -
pubmed
Despite the observation of several adverse events after treatment with
sunitinib , there was no
intracerebral hemorrhage in any
patient . -
pubmed
These findings suggest that
sunitinib combined with radiation therapy can be safely carried out in
RCC patients with
brain metastases and provides a favorable prognosis in these cases . -
pubmed
However , considering their frequent progression , it would be important to carry out careful follow up for these
patients by focusing on the control of
brain metastases . -
pubmed
Quantification of filamentation by uropathogenic
Escherichia coli during experimental
bladder cell infection by using semi - automated image analysis . -
pubmed
Evidence has emerged over the past decade suggesting that this morphological transformation is controlled and reversible and provides selective advantages under certain growth conditions , such as during
infection in
humans . -
pubmed
Used in combination with a flow - chamber based in vitro
cystitis model , we study the factors involved in filament formation by uropathogenic
E. - pubmed
coli (
UPEC ) during
infection . -
pubmed
MicroRNA-22 - 3p is down - regulated in the plasma of Han Chinese
patients with
premature ovarian failure . -
pubmed
PATIENT(S ): A total of 140
individuals with
premature ovarian failure (
POF ) and 140 age- and
body mass index - matched control subjects of Han Chinese ancestry . -
pubmed
RESULT(S ): Fifty - one differentially expressed miRNAs were identified by chip - based discovery stage between ten
patients with
POF and ten control subjects , among which nine miRNAs ( let-7b-5p , let-7c , miR-15b-5p , miR-22 - 3p , miR-23a-3p , miR-23b-3p , miR-24 - 3p , miR-151a-5p , and miR-151b ) were selected and validated . -
pubmed
Correction : Impact of Maternal
HIV Seroconversion during Pregnancy on Early Mother to Child Transmission of
HIV ( MTCT ) Measured at 4 - 8 Weeks Postpartum in South Africa 2011 - 2012 : A National Population - Based Evaluation . -
pubmed
METHODS : From 2009 to 2013 , ten
patients with single - level
Kummell ' s disease accompanied by severe
osteoporosis were enrolled in this study . -
pubmed
No
patient sustained adjacent
fractures after bone cement - augmented percutaneous short segment fixation during the follow - up period . -
pubmed
SUBJECTS / METHODS : We examined 81 well - characterized normoglycemic
men and postmenopausal
women ( & gt;=27 kg m(-2 ) , 45 - 74 years , non - smokers , sedentary , free of
chronic disease ) . -
pubmed
Many species in this genus , including Pseudo -
nitzschia multistriata , can produce
domoic acid , a toxin responsible for
amnesic shellfish poisoning . -
pubmed
Resistance evaluation of Chinese wild Vitis genotypes against
Botrytis cinerea and different responses of resistant and susceptible hosts to the
infection . -
pubmed
When validated with occurrence records for
malaria ,
An . - pubmed
Bedside inferior vena cava filter placement by intravascular ultrasound in
critically ill patients is safe and effective for an extended time . -
pubmed
BACKGROUND : Bedside inferior vena cava filter ( IVCF ) placement by intravascular ultrasound ( IVUS ) guidance has previously been shown to be a safe and effective technique , especially for
critically ill patients , with initial experience of a prospectively implemented algorithm . -
pubmed
The purpose of this study was to evaluate the effectiveness of IVUS - guided filter placement in
critically ill patients with experience now extending out 5 years from implementation . -
pubmed
CONCLUSIONS : On the basis of 5 years of experience with bedside IVCF placement in
critically ill patients , the IVUS - guided IVCF technique continues to be a safe and effective option in this high - risk population , with a time - dependent improvement in outcome measures . -
pubmed
[ The influence of lumbar sympathetic
ganglion radiofrequency thermocoagulation on the activation of microglia in
rats with
diabetic neuropathic pain ] . -
pubmed
OBJECTIVE : To observe the influence of lumbar sympathetic
ganglion radiofrequency thermocoagulation on the activation of spinal microglia in
rats with
diabetic neuropathic pain ( DNP ) . -
pubmed
METHODS : Thirty - six painful
diabetic Sprague - Dawley rats induced by 60 mg / kg
streptozotocin (
STZ ) intraperitoneal injection were randomly divided into
diabetic neuropathic pain group ( group DNP , n=12 ) , Sham operation group ( group Sham , n=12 ) and radiofrequency thermocoagulation group ( group R , n=12 ) . -
pubmed
Topical administration of
hyaluronic acid in
children with recurrent or chronic
middle ear inflammations . -
pubmed
Hyaluronic acid ( HA ) treatment has been successfully performed in
patients with recurrent
upper airway infections or
rhinitis . -
pubmed
The aim of this study was to assess the efficacy and safety of the topical nasal administration of an HA - based compound by investigating its effects in
children with recurrent or chronic
middle ear inflammations and
chronic adenoiditis . -
pubmed
The reduction in the prevalence of
patients with
conductive hearing loss (
CHL ) ( P value = 0.008 ) and those with moderate
CHL ( P value = 0.048 ) was significant in the study group , but not in the control group . -
pubmed
Our findings confirm the safety of intermittent treatment with a topical nasal
sodium hyaluronate solution and are the first to document its beneficial effect on clinical and audiological outcomes in
children with recurrent or chronic
middle ear inflammations associated with
chronic adenoiditis . -
pubmed
Closed - Loop Prevention of
Hypotension in the Heartbeating Brain - Dead
Porcine Model . -
pubmed
Objective : The purpose of this paper is to demonstrate feasibility of a novel closed - loop controlled therapy for prevention of
hypertension in the heartbeating brain - dead
porcine model . -
pubmed
Nearly half of all surgical
patients have moderate to severe
pain postoperatively , and 24 % experience inadequate
pain relief . -
pubmed
Furthermore , over half of the
patients develop chronic
pain after thoracotomies , mastectomies , and limb amputation surgeries . -
pubmed
Human cytomegalovirus is a significant agent of
hepatic involvement in neonates . -
pubmed
PURPOSE : To determine changes in Achilles tendon resting angle ( ATRA ) , heel - rise height ,
patient - reported outcomes , return to play , and occurrence of complications after minimally invasive repair of
Achilles tendon ruptures using nonabsorbable sutures . -
pubmed
METHODS : Between March 2013 and August 2015 , a total of 70
patients ( 58
males , 12
females ) with a mean age of 42 + - 8 years were included and evaluated at 6 weeks and 3 , 6 , 9 , and 12 months after repair of an
Achilles tendon rupture . -
pubmed
Methods We conducted a multicenter , case - control study in which 15
RA patients who developed
PCP were compared with 74
RA patients who did not develop
PCP during
etanercept therapy . -
pubmed
Results
PCP developed within 26 weeks following the first injection of
etanercept in 86.7 % of the
patients . -
pubmed
In
patients having a larger number of risk factors , the cumulative probability of developing
PCP was significantly higher ( p & lt ; 0.001 for patients with two or more risk factors vs. those with no risk factor , and p = 0.001 for patients with one risk factor vs. those with no risk factor ) . -
pubmed
Delayed recovery of the affected finger extensors at chronic stage in a
stroke patient : A case report . -
pubmed
RATIONALE : A 33 - year - old
male presented with complete
weakness of the right extremities due to
corona radiata infarct . -
pubmed
The putative benefit of perioperative
seizure prophylaxis must be weighed against the risks of adverse effects and drug interactions in
patients without a history of
seizures . -
pubmed
Consequently , the authors conducted a systematic review of prospective randomized controlled trials ( RCTs ) that have evaluated the efficacy of perioperative
seizure prophylaxis among
patients without a history of
seizures . -
pubmed
Further , this expected incidence of new - onset
postoperative seizures would require a total of 1258
patients to enroll in a RCT , as determined by a Farrington - Manning noninferiority test performed at the 0.05 level using a noninferiority difference of 5 % . -
pubmed
A large multicenter randomized clinical trial would be required to assess whether perioperative
seizure prophylaxis provides benefit for
patients undergoing
brain tumor resection . -
pubmed
The impact of
volume overload on right heart function in
end - stage renal disease patients on hemodialysis . -
pubmed
PURPOSE : The aim of this study was to evaluate the impact of
volume overload on echocardiographic parameters used for the assessment of the right ventricle ( RV ) and right atrium ( RA ) , to determine volume - independent parameters and to noninvasively investigate the physio - mechanics of RV and
RA by examining end - stage kidney
patients before and after hemodialysis ( HD ) . -
pubmed
Materials and Methods : Using two multicenter retrospective studies on
breast cancer , a pooled analysis was performed among 320
patients with pT1 - 2N1
TNBC . -
pubmed
None of the
patients developed
recurrence or
metastasis . -
pubmed
This study aimed to retrospectively investigate the risk factors of LLN metastasis in clinical lymph node - negative ( cN0 )
PTC patients . -
pubmed
Patients with
tumor in the upper lobe had ~ 3 - fold higher risk of LLN
metastasis compared with
patients with
tumor in other locations ( OR = 2.874 , 95 % CI 1.916 - 4.310 ; P = 0.001 ) . -
pubmed
CONCLUSIONS : Large
tumor size ( & gt ; 20 mm ) ,
tumor located in the upper lobe , multifocality , extrathyroidal extension , and & gt;= 2 CLN
metastases may increase the risk of LLN
metastasis in cN0
PTC patients . -
pubmed
RU47 in two plant species (
potato and
lettuce ) and its biocontrol effect against
Rhizoctonia diseases . -
pubmed
We aimed to assess all randomized controlled trials from the world literature for the purpose of evaluating the clinical outcome - specific efficacy of SCS for the following outcomes : perceived
pain relief or change
pain score , quality of life , functional status , psychological impact , analgesic medication utilization ,
patient satisfaction , and health care cost and utilization . -
pubmed
AIMS :
Anthracycline - based chemotherapy improves survival in
breast cancer patients but is associated with increased risk of
heart failure (
HF ) . -
pubmed
METHODS AND RESULTS : Between 1990 and 1998 the Danish
Breast Cancer Cooperative Group ( DBCG ) 89D trial randomized 980 Danish
women with early
breast cancer to adjuvant
cyclophosphamide ,
epirubicin , and
fluorouracil or
cyclophosphamide ,
methotrexate , and
fluorouracil . -
pubmed
In the
epirubicin treatment group , 23 new cases of
HF were identified vs. 9 in the non -
epirubicin group corresponding to incidence rates per 1000
patient - years of 3.7 [ 95 % confidence interval ( CI ) 2.5 - 5.6 ] vs. 1.4 ( 95 % CI 0.7 - 2.7 ) . -
pubmed
Background : Elevated
homocysteine (
Hcy ) has been reported to be associated with cardiovascular events in
atrial fibrillation (
AF )
patients , while the age - related expression pattern of plasma
Hcy in
AF remains unknown . -
pubmed
The study was aimed to investigate the effect of advanced age on plasma
Hcy levels and its association with
ischemic stroke in non - valvular
AF patients . -
pubmed
Methods : A total of 2562 consecutive
patients with
non - valvular AF and 535 controls were enrolled and divided into six age groups . -
pubmed
Hcy was much higher in
AF patients than in controls at the same age group ( all P & lt ; 0.05 ) . -
pubmed
The proportion of
patients with
hyperhomocysteinemia increased gradually with age from 32.3 % , 29.2 % , 31.2 % , 32.4 % , 45.9 % , to 51.4 % in six age groups . -
pubmed
The concentration of
Hcy in
AF patients with
ischemic stroke increased progressively with age , and was higher than those without
stroke at the same age . -
pubmed
Conclusions : Advanced age was significantly associated with elevated
Hcy levels , which may provide a possible explanation for the progressive increase in
ischemic stroke especially in elderly
AF patients . -
pubmed
This study aimed to assess whether
dienogest (
DNG ) is also effective in
patients with recurrent
endometriosis based on multicenter data of 121
women who were clinically diagnosed as having recurrent
endometriosis and treated for more than 24 weeks with
DNG ( 2 mg daily ) . -
pubmed
In conclusion ,
DNG was found to be effective in reducing the size of
endometriomas and provided symptomatic relief in this cohort of
women with recurrent
endometriosis . -
pubmed
CONCLUSION : Increased anticholinergic load during hospitalization might be a predictor of increased
AP in geriatric
patients . -
pubmed
Thus , studies on normal
mammalian cells are necessary to identify
cytotoxicity and prevent adverse effects of functional foods that contain these dyes . -
pubmed
METHODS : A clinical pathway was created to aid in detecting
patients expected to experience postextubation
stridor and to guide prophylactic treatment . -
pubmed
,CzechRepublic ) and
Carboplatin in chemo - naive advanced
non - squamous NSCLC Iranian
patients . -
pubmed
Conclusion : The combination of
Formeta and
Carboplatin was effective in
advancednon - squamous NSCLC and can be a suitable candidate as first - line treatment in these
patient 's population . -
pubmed
Moreover , if
humans respond similarly , we posit that individuals with specific mtDNA variations may differentially metabolise
carbohydrates , which has implications for a variety of diseases including
cardiovascular disease ,
obesity , and perhaps
Parkinson ' s Disease . -
pubmed
Comparison of hemodynamic parameters that can predict an
aneurysmal rupture : 20
patient - specific models experiment . -
pubmed
Relief of intractable
pruritus with
romidepsin in
patients with
cutaneous T - cell lymphoma : A series of four cases . -
pubmed
The majority of
patients with
CTCL experience
pruritus , which can interfere with daily activities , significantly impact quality of life , and is typically uncontrolled by standard anti -
itch therapies . -
pubmed
Here , we describe the cases of four
patients with debilitating and refractory
pruritus that were resolved with
romidepsin . -
pubmed
The potential for
pruritus relief with
romidepsin should be considered when treating
patients with
CTCL . -
pubmed
Effect of occupation - based interventions in
patients with
haematopoietic malignancies undergoing chemotherapy : A pilot randomised controlled trial . -
pubmed
Genetic analyses of
human fetal retinal pigment epithelium gene expression suggest
ocular disease mechanisms . -
pubmed
MLST provides a powerful solution for molecular epidemiological characterization of bacterial
strains , including
Staphylococcus aureus , by using the sequences of the internal region of seven housekeeping genes . -
pubmed
INTRODUCTION : This study investigates the outcomes and safety of 70 - 150 mum and 100 - 300 mum
doxorubicin drug - eluting bead transarterial chemoembolisation ( DEB - TACE ) in
patients with unresectable
hepatocellular carcinoma (
HCC ) . -
pubmed
METHODS : Retrospective , cohort study of 51
patients treated with
DEB - TACE for unresectable
HCC was studied : 23 with 100 - 300 mum particles and 28 with 70 - 150 mum particles . -
pubmed
At 1 - month follow - up ,
patients treated with 70 - 150 mum had significantly better mRECIST
tumour response compared to 100 - 300 mum ( complete response 38.5 % vs. 19 % ; partial response 57.7 % vs. 42.9 % ; stable disease 0 % vs. 4.8 % ; progressive disease 3.8 % vs. 33.3 % , P = 0.027 ) . -
pubmed
Acute Generalized Exanthematous Pustulosis Caused by the Combination of
Pembrolizumab Plus Chemotherapy in a
Patient With
Squamous - Cell Carcinoma . -
pubmed
Itch (
pruritus ) , specifically chronic
itch associated with disease conditions , significantly impairs the
patient 's quality of life . -
pubmed
Here , we report that intragastrical administration of
bulleyaconitine A (
BLA ) , which has been used for treating
chronic pain for 30 years in China , inhibited
itch - like behaviors induced by intradermal injection of
histamine and
chloroquine in
mice and
rats , dose - dependently . -
pubmed
BACKGROUND :
Epilepsy is the most common chronic
neurologic disorder which affects an estimated 10.5 million
children worldwide . -
pubmed
CONCLUSION : This study revealed that many
children were suffering from uncontrolled
seizure and escalation therapy is being exercised . -
pubmed
Borrelia burgdorferi sensu stricto (
Bbss ) is considered the primary agent of
Lyme disease in North America . -
pubmed
However , multiple genetically diverse Borrelia species encompassing the
Borrelia burgdorferi sensu lato ( Bbsl ) complex and the Relapsing Fever Borrelia (
RFB ) group are capable of causing
tickborne disease . -
pubmed
garinii ( 10 ) , and mixed
infections that included
B. - pubmed
In this analysis , three independent observers quantified and categorized the presence of TILs among
tumor samples from
patients in PlanB. -
pubmed
CASE PRESENTATION : A 26 - year - old
man , with a history of
drug abuse and a victim of domestic violence as a child , presented with
tonic - clonic seizures and
intracranial hypertension three years ago , for which he underwent a craniotomy with the finding of a right frontal
cerebral tuberculoma . -
pubmed
Distinguishing mode of action of compounds inducing
craniofacial malformations in
zebrafish embryos to support dose - response modeling in combined exposures . -
pubmed
Immunotherapy has revolutionized
cancer treatment , yet most
patients do not respond . -
pubmed
METHODS : During 2014 to 2017 24
children and adolescents ( nine female , 15 male , median age 9.7 years ) , were treated for symptomatic
urolithiasis in our institutions . -
pubmed
SETTING : CMCO teaching hospital , Strasbourg University Hospitals , France PATIENTS : All
patients presenting a single endometrial
polyp of size greater than or equal to a centimeter . -
pubmed
Detection of disability worsening in relapsing - remitting
multiple sclerosis patients . -
pubmed
BACKGROUND AND PURPOSE : In
relapsing - remitting multiple sclerosis patients (
RRMS ) disability progressively accumulates over time . -
pubmed
METHODS : A cohort of 7,964
RRMS patients followed for two or more years , with EDSS scores recorded every six months , was selected from the Italian
Multiple Sclerosis (
MS ) Register . -
pubmed
[
Congenital microvillus inclusion disease in a
child ] . -
pubmed
The association between seropositivity to
human toxocariasis and childhood
asthma in northern Iran : a case - control study . -
pubmed
RESULTS : Seropositivity rate was 4.1 % ( 95 % CI , 3.4 - 4.7 % ) in
asthmatic children and 0.86 % ( 95 % CI , 0.71 - 1.0 % ) in controls , suggesting a strong association ( P - value < 0.02 ) . -
pubmed
Comparison of Effects Exerted by 4 %
Articaine Buccal Infiltration and 2 %
Lidocaine Inferior Alveolar Nerve Block on
Pain Perception and Behavioral Feedback of
Children during Pulp Treatment of Mandibular Second Primary Molars . -
pubmed
Results : Of the 38
patients included in the current study , 10 ( 26.3 % ) subjects in the
lidocaine group and nine ( 23.6 % ) in the
articaine group complained of
pain during their dental treatment procedures , but this difference was not statistically significant . -
pubmed
PATIENT CONCERNS : A 55 - year - old
woman presented to the outpatient general surgery department with severe , persistent
abdominal pain . -
pubmed
The
patient was diagnosed with
congenital absence of uterus and vagina , and a sigmoid vaginoplasty was performed 34 years ago . -
pubmed
OUTCOMES : After surgery , the
abdominal pain was relieved , and the
patient reported full recovery during a 6 - month follow - up appointment . -
pubmed
Surgical removal of neovagina can relieve the
pain in
patients who do not have the demand of sexual intercourse . -
pubmed
A striking difference in the detection of a heavy growth of
Streptococcus pyogenes in throat swabs taken from 1054 children with
pharyngitis compared with those from 462 normal children was demonstrated when a standardised technique of quantitative culture was used . -
pubmed
Patients with
vascular disease of the legs were studied by indirectly measuring thigh and ankle
systolic pressures and recording the femoral artery flow profile before and after exercise with the aim of identifying those patients in whom significant
aortoiliac stenosis may not have been diagnosed by angiography . -
pubmed
Resting thigh pressures were reduced in the group of
patients with
aortoiliac disease and with
SFA occlusion . -
pubmed
There was no significant change in thigh pressure with exercise in any group but ankle pressure fell with exercise in the
patients with
aortoiliac disease and with
SFA occlusion . -
pubmed
An unicellular alga ,
Chlorella pyrenoidosa , which had been reported to protect
C3H mice against
sarcoma BP8 , is shown , when injected in Freund 's incomplete adjuvant , to modulate the antibody synthesis induced by immunization with a hapten - carrier complex . -
pubmed
Experimental
hypersensitivity pneumonitis : reduced severity of clinical response following repeated injections of
Micropolyspora faeni antigen . -
pubmed
Methylphenidate and
caffeine in the treatment of
children with minimal
brain dysfunction . -
pubmed
In this double - blind , crossover study of 8
boys with minimal
brain dysfunction , 20 mg of
methylphenidate daily was significantly better than 160 mg of
caffeine in controlling behavior , especially
impulsivity and
hyperactivity , and
methylphenidate alone was superior to decaffeinated coffee and placebo . -
pubmed
Sixteen
men with well - documented
angina pectoris and without previous
myocardial infarction performed a multistage exercise stress test to determine their levels of exercise - induced limitations , characterized by onset of
chest discomfort or electrocardiographic ischemic changes , or both . -
pubmed
We have reported on a
patient with isolated metachronous
renal artery emboli . -
pubmed
Influence of combined administration of
ethyl alcohol with
caffeine and
hydroxyzine on cardiac minute volume and
stroke volume in
rabbits . -
pubmed
However these changes were not observed in the positional tests of a group of 22
patients with
hearing losses attributable to other causes . -
pubmed
Nine
patients with multiple
metastases including liver from
breast cancer were treated with transarterial chemoembolization through hepatic artery using 40 - 50 mg of
4 '- epi - adriamycin and
Lipiodol , followed by 800 - 1,200 mg / day of
medroxyprogesterone acetate . -
pubmed
Seven out of 9
patients died within 6 to 37 months ( mean 15.3 months ) after diagnosis of
liver metastases . -
pubmed
Furthermore , we have been able to demonstrate an age related increase in lymphoproliferative responses to both
PHA and
tetanus in
HIV - infected and control children . -
pubmed
Longitudinal study of solute excretion and glomerular ultrastructure in an experimental model of aging
rats free of
kidney disease . -
pubmed
In the oldest
animals a few foci of interstitial
inflammation occasionally were seen . -
pubmed
These observations indicate that basic age - related changes in kidney structure and function of
rats fed ad libitum can be reduced to a few parameters provided that adequate
strains , diet , and husbandry conditions are selected for experimentation . -
pubmed
Observations of impaired chondrocyte metabolism in
essential fatty acid ( EFA ) deficiency as well as
EFA protection against development of
osteoarthrosis in inbred
mice suggest the existence of a relationship between EFA , chondrocyte metabolism , and
cartilage degeneration . -
pubmed
For all assays , performance declined markedly in 1 degree
HPT patient groups with lower serum
calcium levels . -
pubmed
Eighteen
patients with end - stage symptoms of
primary sclerosing cholangitis were evaluated during a 10 - year period from 1976 to 1986 . -
pubmed
All
patients presented with elevated liver function test results , and six of nine
patients had a history of
ulcerative colitis . -
pubmed
Two of three of the
patients with
biliary cirrhosis died within 1 year after surgery . -
pubmed
For
patients with end - stage
primary sclerosing cholangitis , intrahepatic cholangiojejunostomy provides effective surgical palliation in those without
secondary biliary cirrhosis . -
pubmed
Habituation of the
pain perception threshold was found for control subjects but not for
CLBP patients . -
pubmed
A 63 - year - old white
man with
metastatic small cell carcinoma of the bladder attained a complete remission with a combination of
etoposide and
cisplatin chemotherapy , which has lasted for more than 2 years . -
pubmed
Characteristics of an ovariectomized
osteopenic rat model . -
pubmed
Although
osteoporosis induced by ovariectomy ( Ovx ) in the
rat has been widely used as a model for
postmenopausal osteoporosis in
humans , the findings of different investigators are not always consistent . -
pubmed
The effects of Ovx on
body weight , femoral length , and femoral volume were marked in
rats operated on at the age of 4 weeks , slight in
rats operated on at the age of 52 weeks , and intermediate in
rats operated on at the age of 10 weeks . -
pubmed
Spontaneous electrophysiological activity and excitation by
capsaicin of regenerating sensory fibers has been studied using 1 to 20 - week - old
neuromas induced in
rats by ligating and transecting the saphenous nerve . -
pubmed
Patients with
gastric disorders and those taking medications that affect gastric motility or secretion were excluded . -
pubmed
Administration of antibody , directed against glomerular basement membrane ( GBM )
heparan sulfate - proteoglycan , into a presensitized
rat results in the induction of
membranous nephropathy with subepithelial immune - complex deposits . -
pubmed
A
beta - carboline antagonizes
benzodiazepine actions but does not precipitate the
abstinence syndrome in
cats . -
pubmed
Kappa light chain myeloma developing in a
patient with
chronic neutrophilic leukaemia . -
pubmed
Antibodies to indigenous and laboratory
strains of
Streptococcus mutans in saliva from children with
dental caries and from
caries - free children . -
pubmed
Effective clinical use has been demonstrated in
patients with
cutaneous and systemic candidiasis ,
aspergillosis ,
blastomycosis ,
coccidioidomycosis , cryptococcus and
systemic candidiasis ,
aspergillosis ,
blastomycosis ,
coccidioidomycosis ,
cryptococcus and
histoplasmosis . -
pubmed
We report our experience with the oral
imidazole agent
ketoconazole in the management of 8
patients with significant
urinary candidiasis as judged by elevated urinary candidal counts ( greater than 15,000 / ml . ) -
pubmed
Only 4 of the 8
patients had resolution of
candiduria with
ketoconazole therapy . -
pubmed
[ Immunochemical properties of a soluble immune complex from the blood serum of
cancer patients ] . -
pubmed
The immunologic status of 18
patients with intestinal
lymphangiectasia was studied . -
pubmed
Primary circulating antibody response was tested in five
patients with Vi and
tularemia antigens . -
pubmed
Titers elicited in
patients with the Vi antigen were significantly lower than those seen in a control group , whereas no difference was seen between patient and control responses to the
tularemia antigen . -
pubmed
Lymphocytopenia was noted in
patients with intestinal
lymphangiectasia . -
pubmed
91 % of normal individuals reacted to at least one of the four skin test antigens : purified protein derivative ,
mumps , Trichophyton , and
Candida albicans ; in contrast , only 17 % of patients with intestinal
lymphangiectasia had a positive reaction . -
pubmed
The humoral antibody response to a primary
viral neoplasm (
MSV ) through its entire course in BALB - c
mice . -
pubmed
[ Partial and generalized
convulsive manifestations of
stereotaxic lesions of the brainstem in the
cat ] . -
pubmed
[
Electron microscopic studies under neurophysiologic control of
brain edema in
cats ] . -
pubmed
Morphogenesis of the eye lens in a
mouse strain with
hereditary cataracts . -
pubmed
[ Serum complement profile and its clinical significance in
patients with
hepatocellular carcinoma and
liver cirrhosis ( author 's transl ) ] . -
pubmed
Growth retardation and
renal osteodystrophy in
children with
chronic renal failure . -
pubmed
Height , expressed as standard deviation scores for chronological age and for bone age , was studied in relation to
glomerular filtration rate , bone age delay , and bone histology in 47
children with
chronic renal disease and
GFR less than 80 ml / min/1.73 m2 . -
pubmed
Renal osteodystrophy , which only occurred at
GFR less than 30 ml / min/1.73 m2 , significantly affected height only in
children with
congenital renal disease and
GFR less than 20 ml / min/1.73 m2 . -
pubmed
The pathophysiological effects of experimental larval challenge with a mixed
trichostrongyle infection were measured in
ewes which had previously grazed contaminated pasture . -
pubmed
Lymphocyte response in
mice infected with the Indonesian and Formosan
strains of
Schistosoma japonicum to concanavalin A , and to worm and egg antigens . -
pubmed
The differences may have been associated with the number of worms developing in the
mice since the adult worm recovery for the Indonesian
strain was nearly twice that of recoveries from
mice infected with the Formosan
strain . -
pubmed
Peripheral blood mononuclear cells ( PBMC ) from 12
patients with
Graves ' disease and 9 healthy subjects were cultured with peptides for 3 days . -
pubmed
Four hundred forty - five bronchoalveolar lavage specimens from patients with the
human immunodeficiency virus were preserved in Saccomano 's
fixative and stained for
Pneumocystis carinii cysts by a modified method with Fungi - Fluor Solution A ( Polysciences , Warrington , Pa ) and the Genetic Systems
Pneumocystis carinii Immunofluorescence Antibody ( Genetic Systems Corp , Seattle , Wash ) . -
pubmed
The sensitivity for detecting
cysts of
P carinii was significantly greater with the Genetic Systems stain ( P & lt ; .01 ) . -
pubmed
However , there is clear evidence that the incidence of such vessels in
patients with
ureteropelvic junction obstruction is significantly higher than in the general population . -
pubmed
Bacterial translocation : nursing implications in the care of patients with
neutropenia . -
pubmed
PURPOSE / OBJECTIVES : To describe
bacterial translocation ; the potential causes and influencing factors of
bacterial translocation ; the anatomy , physiology , and immunology of the small intestine ; and the significance of bacterial translocation in patients with
cancer . -
pubmed
This process called
bacterial translocation may be responsible for symptoms such as
fever of unknown origin in these patients . -
pubmed
[ Generation of active forms of
oxygen by alveolar macrophages in
patients with
bronchial asthma ] . -
pubmed
Exercise - induced changes in
oxygen saturation in the calf muscles of elderly
subjects with
peripheral vascular disease . -
pubmed
In summary , NIRS measurements show promise as a method of evaluating the kinetics of
oxygen saturation , particularly in
patients with mild
peripheral vascular disease . -
pubmed
The immediate hematopoietic response to
3 '- azido-3 '- deoxythymidine (
AZT ) was characterized in an unperturbed and regenerating
mouse marrow model to identify the in vivo hematopoietic targets of
AZT and test whether
AZT toxicity is dependent on the proliferative activity of the hematopoietic targets . -
pubmed
When administered to
mice whose marrow was regenerating from total - body irradiation (
TBI ) and subsequent bone marrow transplantation ( high proliferative fraction ) , 240 mg / kg
AZT caused considerable reductions of all hematopoietic cell stages even when given as a single IV injection . -
pubmed
The morphological and physiological properties of this
strain suggest that it belongs to the genus Arthrobacter , and the isolate was therefore designated
Arthrobacter strain 45 - 8A. -
pubmed
They are also indistinguishable from antibodies induced by a proposed vaccine to
cholesterol that is currently in late preclinical development for prevention of
hypercholesterolemia in
humans . -
pubmed
Observation of
baker 's
yeast strains used in biotransformation by atomic force microscopy . -
pubmed
In those
persons having taken 131J , frequency of the thyroid gland
neoplasia gets increased almost 6 - fold as compared to general population . -
pubmed
Thirty
patients ( 18
men , 12
women , mean age 56 + /- 12 years ) with
systemic amyloidosis verified by biopsy and strong indications of
cardiac amyloidosis comprised the study group , with 30 healthy age- and sex - matched individuals serving as controls . -
pubmed
All
patients and controls underwent 24 - h Holter monitoring for
arrhythmias . -
pubmed
Left ventricular ( LV ) wall thickening was found in all
patients with
cardiac amyloidosis . -
pubmed
The LV mass in the
patients with
cardiac amyloidosis was significantly greater than that of the control group , as was the ratio LV mass / body surface area ( p & lt ; 0.001 ) . -
pubmed
changes in biochemical markers of bone formation and resorption were comparable in
patients with
quadriplegia and
paraplegia , except for a greater increase in quadriplegics in
pyridinoline , expressed as a percentage of baseline . -
pubmed
Subjects were assessed at regular intervals with the Yale - Brown Obsessive Compulsive Scale Modified for BDD ( BDD - YBOCS ) , the Clinical Global Impressions ( CGI ) scale , the Hamilton Rating Scale for
Depression , the Brown Assessment of Beliefs Scale , and other measures . -
pubmed
We report 2 cases of primary
muscular hydatosis of the thigh in a 30 - year -
woman and a 75 - year -
man . -
pubmed
OBJECTIVE : To compare the efficacy of intranasally administered
azelastine to
budesonide , at their respectively recommended dosage , on the symptoms of perennial
rhinitis patients . -
pubmed
The 195
patients ( with at least a 2 - year history of
perennial allergic rhinitis ) recorded individual nasal symptom scores , the degree of symptom control achieved and any adverse events experienced over a 2 - week baseline period and a 6 - week treatment period . -
pubmed
In
patients treated with
budesonide , there were also significantly larger reductions from baseline values in combined nasal symptom scores ( P & lt ; .01 ) and in scores for all individual
nasal symptoms ( P & lt ; or = .05 ) compared with those treated with
azelastine . -
pubmed
Nonsteroidal anti - inflammatory drugs ( NSAIDs ) have been shown to cause apoptosis in several cell lines including transformed
chicken embryo fibroblasts and
human colon cancer cells . -
pubmed
The authors present results of manifold evaluation of stomach in 109
patients with
vibration disease caused by various vibration characteristics . -
pubmed
Usefulness of the electrocardiogram in predicting stent patency in
patients presenting with
chest pain within one month of coronary stenting . -
pubmed
Considering the experimental work on
paracoccidioidomycosis , 0.03 ml of a fungal suspension obtained from a biopsy of a
Jorge Lobo ' s Disease patient were inoculated into both hind foot pads of 32 six week - old BALB / c
mice of both sexes . -
pubmed
Based on fungal count , viability index before and after inoculation , presence of macroscopic lesions and histopathological findings similar to the findings in
humans , the authors believe that BALB / c
mice may be a good experimental model to study
Jorge Lobo ' s Disease , mainly regarding therapeutic evaluation . -
pubmed
Microinjection through the round window membrane has been found to represent a method for vector delivery in intracochlear gene transfer in
animal models but breaches the round window membrane , making it necessary to evaluate
animals for possible postinjection
hearing loss . -
pubmed
In this preliminary study saline microinjection through the round window membrane did not cause permanent
hearing loss in the
guinea pigs tested , and any damage caused by microinjection appeared to be reversible . -
pubmed
We describe the clinical course of a series of
patients who developed
agranulocytosis while taking this drug , and we estimate the risk by means of both a case - control and a case - population strategy . -
pubmed
From July 1994 to December 1996 , 41
patients with previously untreated , advanced bulky
squamous cell carcinoma arising from the buccal mucosa (
BSCC ) were enrolled . -
pubmed
PATIENTS : Biopsies were taken in 13
patients with
tumors of the petrous apex and petroclival region . -
pubmed
Three other
patients had
metastases (
carcinoma of the breast ,
bronchial carcinoma , and unknown origin ) . -
pubmed
Three
patients had a
meningioma , and another three a
chordoma . -
pubmed
OBJECTIVE : To describe an approach to the treatment of
eruptive syringomas in an African American
patient with a combination of
trichloroacetic acid (
TCA ) and
CO2 laser resurfacing , providing acceptable cosmetic results without significant side effects . -
pubmed
METHODS : We describe an African American
patient with eruptive
syringomas of the face treated with a combination of
TCA and
CO2 laser resurfacing with good results . -
pubmed
The resistances to
starvation ,
paraquat , and cold in
flies from 1 to 7 week - old have been measured . -
pubmed
Breast MR imaging is a useful tool for staging
breast cancer patients , and staging is more accurate with MR imaging than with conventional imaging techniques . -
pubmed
Bile acids derived from intestinal
bacterial metabolism and transported to the breast in plasma may influence risk of
breast cancer . -
pubmed
Suppression of intestinal
polyposis in
Apc ( Min /+ ) mice by inhibiting
nitric oxide production . -
pubmed
The genome of
Rickettsia tsutsugamushi was detected and identified as the Kawasaki serotype
strain . -
pubmed
Renal scarring caused by
vesicoureteric reflux and
urinary infection : a study in
pigs . -
pubmed
The mechanisms of
reflux nephropathy scarring are best explained by a
piglet model in which
vesicoureteric reflux allows infected urine to enter those segments of renal parenchyme that are drained by compound papillae . -
pubmed
Adult
pigs were exposed to
urine infection after surgery to produce unilateral
vesicoureteric reflux . -
pubmed
One week later
Escherichia coli was injected into the urinary bladder to produce
cystitis . -
pubmed
The risk of
reflux nephropathy scarring is not eliminated by maturation of the kidney in
pigs . -
pubmed
It is unlikely that the much - reduced risk of initiating
scarring that is seen in older children with
urine infections is due to a protective maturation of the
human kidney . -
pubmed
A possible explanation is that most
children born with risk factors for developing
scarring will have already sustained
scars when very young . -
pubmed
The lung , the organ that is predominantly responsible for the morbidity and mortality in
CF patients , is accessible by a non - invasive method , the inhalation of aerosols . -
pubmed
PURPOSE : To describe a combined pharmacological and surgical approach to treating
acquired nystagmus in a
patient with
multiple sclerosis . -
pubmed
METHODS : A 40 - year - old
patient with acquired
horizontal and vertical nystagmus and severe
oscillopsia secondary to
multiple sclerosis had combined treatment with
gabapentin and a vertical Kestenbaum - type procedure . -
pubmed
RESULTS : After
gabapentin treatment ( 3,000 mg orally daily ) the
horizontal nystagmus was significantly reduced , and the
patient developed a marked chin - up position . -
pubmed
In particular , comprehension is dependent on anterolateral and ventral left temporal regions , as suggested by observations on patients with
semantic dementia , as well as posterior regions described in studies on aphasic
stroke patients . -
pubmed
The only frontal contribution was confined to the ventrolateral left prefrontal cortex , compatible with observations that comprehension of simple speech is preserved in
patients with left
posterior frontal infarction . -
pubmed
Magnetic resonance imaging in
patients diagnosed with
ductal carcinoma - in - situ : value in the diagnosis of residual disease , occult invasion , and multicentricity . -
pubmed
The most significant mode of
infection by the inhabitants was the raw eating of sweetfish which commonly harbour metacercariae of
M. - pubmed
The
infection in the sweetfish
Plecoglossus altivelis as the second intermediate host was first observed from May with low level of
infection and the intensity of
infection in a fish rapidly increased until reaching a peak in October when sweetfish season normally ends . -
pubmed
[ Effect of
phenadone on blood pressure in
rabbits in experimental
cholesterol arteriosclerosis and following implantation of heterogenous tissue ] . -
pubmed
Infants with
Ureaplasma urealyticum in the lower respiratory tract are at risk for
chronic lung disease (
CLD ) or
bronchopulmonary dysplasia (
BPD ) but causality has been difficult to prove . -
pubmed
OBJECTIVE : The pathogenetic mechanism of
tobacco - related
cardiovascular diseases is still not well defined . -
pubmed
Extracranial injuries including
bone fractures were the most common associated
injuries and medical complications such as
spasticity and
contractures were present in more than half of the
patients . -
pubmed
TBI survivors in this study made statistically significant functional improvements . -
pubmed
Since the beverage was recently demonstrated to exert
hypotensive effect in
rats , we analyzed its underlying mechanisms in this study . -
pubmed
The objectives of the current study were to evaluate the outcomes of
patients with T2b , locally persistent
NPC who were treated with high - dose - rate ( HDR ) intracavitary brachytherapy and to explore whether routine brachytherapy boost could improve the local control of
patients who had T2b
NPC at initial diagnosis . -
pubmed
METHODS : Thirty - four
patients with locally persistent
NPC who were treated during 1992 - 2000 with HDR intracavitary brachytherapy were analyzed retrospectively . -
pubmed
To compare the efficacy of brachytherapy , another 403 consecutive
patients with nonmetastatic T2b
NPC who were treated with curative intent by external radiotherapy ( ERT ) during the same period were evaluated . -
pubmed
CONCLUSIONS : The results suggested that
patients with T2b
NPC who have locally persistent disease can be salvaged effectively with brachytherapy . -
pubmed
METHODS : Five
patients diagnosed as having
pemphigus vulgaris and
pemphigus foliaceus were treated with the monoclonal antibody
rituximab . -
pubmed
We extracted and isolated three natural
styryl lactones from
Goniothalamus griffithii Hook f. Thoms and investigated their
cytotoxicity on a panel of three hepatocyte cell lines ,
HepG2 , drug resistant
HepG2 (
HepG2 - R ) and primary cultured normal
mice hepatocyte in order to find candidates of potential anti -
cancer drugs which have low toxicity on normal cells and high effect on
tumors or
drug resistant tumors . -
pubmed
All the three
styryl lactones showed evident
cytotoxic activities on both
HepG2 and
HepG2 - R cell lines ; however ,
gonithalamin and
goniodiol shows less toxicity on normal
mice hepatocyte as the IC(50 ) values of them on normal
mice hepatocyte were about three times of that on
HepG2 . -
pubmed
METHODS : Seventeen eyes of 15
patients suffering from
secondary glaucoma following pars plana vitrectomy underwent Ahmed valve implantation . -
pubmed
Third - degree
atrioventricular block in 21
cats ( 1997 - 2004 ) . -
pubmed
The effect of 3rd - degree
atrioventricular block on long - term outcome in
cats is unknown . -
pubmed
Clinical findings and long - term outcome of 21
cats with 3rd - degree
atrioventricular block were studied retrospectively . -
pubmed
Presenting signs included
respiratory distress or collapse , but 6
cats had no clinical signs of disease . -
pubmed
Eight
cats had
congestive heart failure (
CHF ) at the time that 3rd - degree
atrioventricular block was detected . -
pubmed
Heart rates ranged from 80 to 140 beats per minute ( bpm ; median 120 bpm ) with no difference in heart rate between
cats with and those without
CHF . -
pubmed
Eleven of 18
cats that had echocardiograms had structural
cardiac disease , and 6
cats had cardiac changes consistent with concurrent
systemic disease . -
pubmed
One
cat had
atrioventricular nodal lesions detected on histologic examination . -
pubmed
Survival did not differ between
cats with or without
CHF or between
cats with or without structural
cardiac disease . -
pubmed
Thirteen
cats with 3rd - degree
atrioventricular block survived & gt ; 1 year after diagnosis , regardless of presenting signs or underlying
cardiac disease . -
pubmed
Third - degree
heart block in
cats is often not immediately life threatening . -
pubmed
METHODS AND RESULTS : Eighty consecutive
patients ( pts ) were treated for paroxysmal episodes of
AF by segmental ostial ablation of all pulmonary veins and right atrial isthmus ablation . -
pubmed
PURPOSE : To evaluate the effect of
cyclosporine 0.05 % ophthalmic emulsion ( Restasis , Allergan , Inc. , Irvine , CA ) on contact lens comfort and reducing
dry eye symptoms in
patients with
contact lens intolerance . -
pubmed
METHODS : A 5 - week , randomized , investigator - masked study of 17
patients with self - reported contact lens - related
dryness . -
pubmed
The overall repair failure rate was 1.6 % ( 2 cases ) , with the failures occurring in
patients with grade 3 leaks , including 1 who developed
meningitis ; there was no failure of grades 1 and 2 leaks . -
pubmed
Cost - utility analysis of different
peg - interferon alpha-2b plus
ribavirin treatment strategies as initial therapy for naive Chinese
patients with
chronic hepatitis C. -
pubmed
However , no cost - effectiveness data have been published using the clinical data from the peg - interferon alpha-2b and
ribavirin in the treatment of
patients with
hepatitis C in Taiwan . -
pubmed
CONCLUSIONS :
Peg - interferon alpha-2b plus
ribavirin combination for 24 weeks therapy in all genotype
patients should reduce the incidence of
liver complications , prolong life , improve quality of life and be cost - effective for the initial treatment of
chronic hepatitis C. -
pubmed
Zingiber officinale Roscoe alone and in combination with
alpha - tocopherol protect the kidney against
cisplatin - induced
acute renal failure . -
pubmed
The nephroprotective effects of
ethanol extract of
Zingiber officinale alone and in combination with
vitamin E (
alpha - tocopherol ) were evaluated using
cisplatin ( single dose of 10 mg / kg body wt , i.p ) induced
acute renal damage in
mice . -
pubmed
We used the
p53 ( R172P ) knock - in mouse , which is unable to induce apoptosis but retains intact cell - cycle arrest and cellular senescence pathways , to show that spontaneous
tumorigenesis is potently repressed in
Terc -/- p53 ( R172P ) mice . -
pubmed
One
patient in each group died after extubation , and
atelectasia occurred in one
patient given
methylprednisolone . -
pubmed
Outcome after liver re - transplantation in
patients with recurrent
chronic hepatitis C. -
pubmed
The identification of factors associated which improved long - term results may help identify
hepatitis C positive
patients who benefit from liver retransplantation . -
pubmed
Outcome after liver retransplantation for
recurrent hepatitis C was analyzed in 18
patients ( group 1 ) and compared with hepatitis C positive
patients undergoing liver retransplantation for initial nonfunction ( group 2 , n=11 ) and
patients with liver retransplantation for other indications ( group 3 , n=169 ) . -
pubmed
Five - year survival after retransplantation in
patients with
recurrent hepatitis C is similar to that in
patients undergoing liver retransplantation for other indications . -
pubmed
Comparison of extended - release
metformin in combination with a
sulfonylurea (
glyburide ) to
sulfonylurea monotherapy in adult
patients with
type 2 diabetes : a multicenter , double - blind , randomized , controlled , phase III study . -
pubmed
OBJECTIVE : The purpose for this study was to compare the efficacy and tolerability of extended - release
metformin (
MER ) administered with a
sulfonylurea (
glyburide ) to
sulfonylurea monotherapy in
patients with
type 2 diabetes . -
pubmed
METHODS : This multicenter , double - blind , randomized , controlled study enrolled adult
patients with
type 2 diabetes who were either drug naive or previously treated with oral diabetic medications and who had not achieved glycemic control . -
pubmed
OBJECTIVE : The aim of the study was to evaluate the effectiveness of an intervention that targeted both anxious and
aggressive behaviors in
children with
anxiety disorders and comorbid
aggression by parent report . -
pubmed
While the use of synthetic agents , especially those targeting molecules , is an attractive and reasonable approach to prevent
carcinogenesis , it should be noted that traditional herbs and
spices also exist along with their active constituents , which have been demonstrated to disrupt inflammatory signal transduction pathways . -
pubmed
Notably , this phytochemical has exhibited a wide range of
cancer prevention activities in several
rodent models of
inflammation - associated
carcinogenesis . -
pubmed
Intracardiac
thrombosis and
embolism in
patients with
cardiac amyloidosis . -
pubmed
BACKGROUND :
Patients with
primary amyloidosis (
AL type ) have a poor prognosis , in part due to frequent
cardiac involvement . -
pubmed
Effect of
vitamins C and E supplementation on peripheral oxidative stress markers and pregnancy rate in
women with
endometriosis . -
pubmed
OBJECTIVE : To determine whether
vitamins C and E supplementation lowers oxidative stress marker levels and improves pregnancy rate in
women with
endometriosis . -
pubmed
METHODS : Thirty - four
women with
endometriosis received a bar containing
vitamins C and E ( 343 mg and 84 mg , respectively ) or placebo for 6 months . -
pubmed
SUMMARY :
Fenofibrate therapy was initiated for a 60 - year old Hispanic
man with stage 4
chronic kidney disease (
CKD ) for the treatment of
hypertriglyceridemia . -
pubmed
probability scale indicated that there was a possible association between
fenofibrate and
renal dysfunction in this
patient . -
pubmed
CONCLUSION : A 60 - year - old
patient developed
renal impairment after receiving
fenofibrate for the treatment of
hypertriglyceridemia . -
pubmed
Observed frequency of
OSAS in
diabetic patients with
DAN varies between 26 % and 30 % . -
pubmed
,
daytime sleepiness , measured by Epworth Sleepiness Scale , ESS ) in
patients with suspected
OSAS . -
pubmed
We examined 196
patients suspected of
sleep apnea ( 52 female , 144 male , mean age 58.7 yrs , mean BMI 30.57 kg / m2 ) . -
pubmed
All
patients underwent overnight polysomnography and were tested for
autonomic neuropathy by a method of measuring heart rate variabilty and heart rate response to the Valsalva maneuver , standing and deep breathing using a computerized data analysis system . -
pubmed
Eighty
diabetic subjects : 52 DAN- , 28 DAN+ ; 116
subjects without
diabetes : 101 without
autonomic neuropathy (
AN ) , 15 AN+ . -
pubmed
Defining
OSAS as AHI>5 / h and ESS - Score>9 , 46 % of the
diabetic patients DAN+ were positive , whereas in the DAN- group 61 % met the criteria ( non - diabetic
patients without
AN 50.5 % ; with
AN : 60 % ) . -
pubmed
Although the group of
diabetic patients with
autonomic neuropathy had the lowest percentage of
OSAS , statistical analysis showed no significance in comparisons between DAN-/DAN+ or
diabetic / non -
diabetic . -
pubmed
METHODS : Study subjects comprised all consecutive
patients with noninfectious
posterior uveitis who were treated at the Duke Eye Center from March 2004 to July 2007 , and followed for at least nine months , in whom a
fluocinolone acetonide implant was initially inserted , and in whom the implant was replaced , or a second implant was inserted because of recurrent
inflammation . -
pubmed
Acute
hemorrhagic pancreatitis ; study of a
patient having disseminated
fat necrosis ,
hypocalcemia ,
hypopotassemia ,
uremia ,
diabetes mellitus ,
ascites and bilateral
hydrothorax . -
pubmed
QTL for the thermotolerance effect of heat hardening , knockdown resistance to heat and
chill -
coma recovery in an intercontinental set of recombinant inbred lines of
Drosophila melanogaster . -
pubmed
Seroprevalence and potential risk of
bovine brucellosis in zerograzing and pastoral dairy systems in Uganda . -
pubmed
A total of 723
cattle comprised of 497 animals from the pastoral system and 226 animals from the zerograzing system were tested for antibodies against natural
B. - pubmed
The animal - level seroprevalence and within - herd range of
brucellosis in
cattle in the pastoral system were 34.0 % ( 95 % CI : 29.9 , 38.1 ) and 8.1 - 75.9 % , while for those in the zerograzing system were 3.3 % ( 95 % CI : 0.9 , 5.7 ) and 0 - 9.0 % . -
pubmed
Accordingly , the objectives of this study are to analyze a North American cohort of patients with
ALD with or without a secondary diagnosis of
liver disease to estimate ( i ) the incidence of
PD and its predictors , as well as ( ii ) the effect of
PD on
patient survival . -
pubmed
METHODS : We conducted a retrospective review of all
patients transplanted for
ALD surviving for more than 3 months after transplant . -
pubmed
Overall 53 % of
patients had co - existing causes of
liver dysfunction . -
pubmed
In all
patients , the risk of
AD was 24 % and PD 13 % . -
pubmed
DESIGN : Serum proteins were analyzed in 26 biochemically active
AIP patients that were classified according to the EPI ( European Porphyria Initiative ) guidelines as follows : ( i )
patients who presented a single acute attack having remained so far free of clinical symptoms ; ( ii )
patients who present recurrent attacks or chronic symptoms associated with exacerbations of
AIP . -
pubmed
CONCLUSIONS : This first study in
humans suggests that the clinical expression
AIP is associated with a state of under - nutrition and/or with
hepatic inflammation due to the sustained accumulation of
heme - precursors . -
pubmed
Hypopituitarism in
adults seems to be a dynamic condition where new deficiencies can appear years after the initial diagnosis , and careful endocrine follow - up of all
hypopituitary patients , including those with
IGHD , is warranted . -
pubmed
Patients were exposed to a 904 - nm infrared laser ( 50 kHz , 28.4 J / cm(2 ) energy density , 40 % duty cycle ,
spot size 0.8 cm ) . -
pubmed
Loss of photic entrainment at low illuminances in
rats with acute
photoreceptor degeneration . -
pubmed
Respiration - related laryngeal electromyography in
children with bilateral
vocal fold paralysis . -
pubmed
We present 2 case reports to demonstrate the relationship between laryngeal muscle activity and respiration in
children with bilateral
vocal fold paralysis (
BVFP ) by simultaneous laryngeal electromyography ( EMG ) with recording of chest wall movement and intercostal muscle EMG . -
pubmed
Laryngeal EMG should be combined with intercostal muscle EMG in the evaluation of
children with significant
vocal fold dyfunction of either central or peripheral origin . -
pubmed
CONCLUSION : Atypical
IM may better reveal the precancerous nature of
IM and could be a helpful indicator in the clinical follow up of
patients . -
pubmed
METHODS : Adult asthmatic
patients with suspected
AERD who underwent BC with
L - ASA were included in the study . -
pubmed
After BC , 4
patients had an early
asthmatic response , 1 had a dual response , and 2 had isolated late responses . -
pubmed
Prevalently reported in
children ,
eosinophilic esophagitis has recently been reported with increased frequency also in adults . -
pubmed
PATIENTS AND METHODS : We retrospectively reviewed the histological data of consecutive
patients with a diagnosis of
esophagitis or
reflux disease in the period September 2004 - September 2008 . -
pubmed
A Case of
Lobar Pneumonia with
Bacteraemia Caused by the Haemolytic
Streptococcus . -
pubmed
OBJECTIVE : Presentation of 8
patients with
subependymal giant - cell astrocytomas (
SGCA ) associated with
tuberous sclerosis complex (
TSC ) . -
pubmed
MATERIAL AND METHODS : There are 8
patients , 6
males and 2
females with
TSC , who presented with the
tumour between the neonatal period and 24 years . -
pubmed
Three of the
patients were admitted urgently due to
blindness and
increased intracranial pressure . -
pubmed
Incomplete removal of the
tumour has always been bad solution as it resulted in the
death of the
patient ( in one case ) or further surgery operation in the short term . -
pubmed
Only one
patient developed the
tumour suddenly from pre - existing subependymal nodules from the childhood and they had to be removed at 24 years of age . -
pubmed
By contrast , 32
patients with
TSC and images of subependymal nodules whose CT or MR progress was followed up for between 10 and 30 years did not develop a
tumour . -
pubmed
Effect of
flavonol glycoside in
mulberry (
Morus alba L. ) leaf on
glucose metabolism and oxidative stress in liver in diet - induced
obese mice . -
pubmed
BACKGROUND :
Mulberry therapies on
type 2 diabetic patients or
streptozotocin - induced
diabetic rats have been reported to improve fasting blood
glucose levels . -
pubmed
We investigated the effects of dietary consumption of
mulberry - leaf powder and purified
quercetin 3 -( 6 - malonylglucoside ) , the quantitatively major
flavonol glycoside in
mulberry leaves , on
glucose and lipid metabolism in high - fat diet - induced
obese mice . -
pubmed
CONCLUSION : Dietary consumption of Q3MG , the quantitatively major
flavonol glycoside in
mulberry leaves , improved
hyperglycemia in
obese mice and reduced oxidative stress in the liver . -
pubmed
These results suggest that younger children may require a longer isolation period and that patients with
pneumonia may require treatment that is more aggressive than standard therapy for
pandemic ( H1N1 ) 2009 virus . -
pubmed
Nasopharyngeal carriage rate of
Streptococcus pneumoniae in children with
sickle cell disease before and after the introduction of heptavalent
pneumococcal conjugate vaccine . -
pubmed
Children with
sickle cell disease (
SCD ) are at high risk of severe
infection with Streptococcus pneumoniae (
SP ) . -
pubmed
From 2002 , all children aged & lt;5 years in the UK with
SCD were recommended 7 - valent
pneumococcal conjugate vaccine (
PCV-7 ) in infancy and 23 - valent
pneumococcal polysaccharide vaccine boosting , in addition to regular
penicillin prophylaxis . -
pubmed
The introduction of
PCV-7 appears to be associated with a shift in distribution of serotypes carried by children with
SCD . -
pubmed
In selected
patients who have a solitary
intracardiac melanoma , surgical resection can provide relief from clinical symptoms and minimize potential cardiac sequelae of the
tumor . -
pubmed
Herein , we present the case of a 31 - year - old
man who had a right
atrial metastatic melanoma of unknown primary origin . -
pubmed
Accordingly , intratumoral injection of HS - TEX could induce specific antitumor immune response more efficiently than that by
tumor - derived exosomes , thus inhibiting
tumor growth and prolonging survival of
tumor - bearing
mice more significantly . -
pubmed
BACKGROUND : Because the receptor for
parvovirus B19 (
B19V ) is on red blood cells ( RBCs ) , we investigated
B19V distribution in blood by in vitro spiking experiments and evaluated viral compartmentalization and persistence in natural
infection . -
pubmed
In this study we examined the effect of the long - acting opioid antagonist
naltrexone on the
allodynia - like effect of
spinal ischemia in
rats . -
pubmed
An
allodynia - like sensory disturbance , where the
animals reacted by vocalization to non - noxious mechanical stimuli in the flank area , was consistently seen during several days after
ischemia . -
pubmed
There is no doubt that
arterial hypertension in dialysis
patients as well as in patients without
renal disease is deleterious for the cardiovascular system . -
pubmed
We report thirty
patients of
TAO in the age - group of 20 - 50 years were treated with the Ilizarov method . -
pubmed
MATERIALS AND METHODS :
Patients with severe
rest pain ( n=30 ) , absent distal pulsation ( n=30 ) and
ulcer ( n=6 ) and/or
gangrene of the toes ( n=4 ) , who had failed the conservative pharmacological modalities of treatment were included . -
pubmed
RESULTS : Of the 30
cases , 25
patients became
pain free while 1 had partial relief of
pain . -
pubmed
The four
patients worsened on treatment and developed frank
infection were amputed . -
pubmed
There were two cases of
osteomyelitis in our series ; both healed after debridement and both
patients had good result , with relief of
pain . -
pubmed
Cancer cells were added to platelet poor plasma from healthy
volunteers . -
pubmed
The most heat - resistant
strain of each of the milk - borne pathogens
Staphylococcus aureus ,
Yersinia enterocolitica , pathogenic
Escherichia coli ,
Cronobacter sakazakii ( formerly known as
Enterobacter sakazakii ) ,
Listeria monocytogenes , and
Salmonella was selected to obtain the worst - case scenario in heat inactivation trials using a pilot - plant - scale pasteurizer . -
pubmed
Effect of thumb joint mobilization on pressure
pain threshold in elderly
patients with thumb
carpometacarpal osteoarthritis . -
pubmed
METHODS : Twenty - eight
patients between 70 and 90 years old with secondary
TCOA were randomized into glide mobilization and sham groups . -
pubmed
METHODS : Twenty - eight
patients with
pSS treated with
rituximab ( 1000 mg ) infusions on days 1 and 15 were included in the study . -
pubmed
Five
stroke survivors with chronic
hemiparesis completed 18 one - hour training sessions over 6 weeks . -
pubmed
This is a retrospective single - centre study carried out in
patients with a
recurrence of an oral cavity or
oropharyngeal carcinoma or a second appearance of
tumour in a previously irradiated area . -
pubmed
METHODS : Between June 2003 and December 2010 , 90
patients with
musculoskeletal tumor underwent
tumor resection and soft tissue reconstruction . -
pubmed
There were 59
males and 31
females with a median age of 37.2 years ( range , 9 - 85 years ) , including 52
bone tumors and 38
soft tissue tumors . -
pubmed
Local
tumor recurrence was observed in 6
patients , who received second resection at 2 - 27 months ( mean , 8.2 months ) after operation . -
pubmed
Mitochondria - addressed cations decelerate the leaf senescence and
death in
Arabidopsis thaliana and increase the vegetative period and improve crop structure of the
wheat Triticum aestivum . -
pubmed
Plastoquinone or its methylated form covalently bound to the membrane - penetrating
decyltriphenylphosphonium cation (
SkQ1 and
SkQ3 ) retarded the senescence of
Arabidopsis thaliana rosette leaves and their
death . -
pubmed
These results indicate that the tested compounds act as antioxidants , that ROS participate in aging and
death of
A. - pubmed
CONCLUSIONS : The current findings suggest that
estrogen - alone use in postmenopausal
women results in a modest but sustained reduction in the frequency of
joint pain . -
pubmed
In vivo
human tissue compliance of the
normal and
cancer gastrointestinal tissue is unknown . -
pubmed
The data were used to calibrate the CRTCMS to predict
cancerous tissue in a further 12
patients ( 3
cancer esophagus and 9
cancer stomach ) involving 175 measurements . -
pubmed
All consecutive
patients admitted for workup of
neurosyphilis under the Social Hygiene Service , in Hong Kong , were included . -
pubmed
Using diagnostic case definition standard stipulated in the IUSTI 2008 guidelines , 17
patients satisfied the diagnosis of
neurosyphilis . -
pubmed
The most common organisms isolated in early onset and late onset
VAP was
Pseudomonas aeruginosa ,
E.coli and
Acinetobacter baumanii . -
pubmed
PATIENTS OR OTHER PARTICIPANTS : Twenty - five female college
athletes ( age = 19.4 + - 1.4 years , height = 170.2 + - 7.4 cm , mass = 67.3 + - 10.0 kg ) with histories of unilateral
ankle sprain . -
pubmed
OBJECTIVE :
Soybean phytoestrogens , such as
genistein and
daidzein , reduce
climacteric symptoms and the risk of certain
chronic diseases such as
cancer and
cardiovascular diseases . -
pubmed
CONCLUSIONS : The use of tissue expanders to treat ischial pressure
ulcers , especially in
patients with long life expectancy , offers important advantages over other approaches . -
pubmed
A cross - sectional study was conducted in a university hospital , enrolling 40
patients with
pre - eclampsia ( case group ) and 40 healthy normotensive pregnant
women ( control group ) . -
pubmed
Total antioxidative activity was similar between pre -
eclamptic and normotensive
patients ( p & gt ; 0.05 ) . -
pubmed
ECM components were visualized by Sirius red and immunohistochemistry staining and quantified by western blot analysis in
mice with
unilateral ureteral obstruction (
UUO ) . -
pubmed
METHODS : This randomized clinical trial enrolled
patients with
chronic wounds between March 2012 and December 2013 . -
pubmed
Patients who achieved
wound closure were followed up for a minimum of 6 months to evaluate the quality of healing . -
pubmed
More
patients achieved complete
wound closure in the skin cell group than in the control group ( 41 versus 34
patients ; P = 0 035 ) . -
pubmed
Aggravation of
hepatopulmonary syndrome after
sildenafil treatment in a
patient with coexisting
portopulmonary hypertension . -
pubmed
We report a case of a
patient who had both
HPS and
PPHTN at the time of presentation . -
pubmed
Boron ( B ) deficiency has seriously negative effect on
citrus production . -
pubmed
To understand the molecular basis of
citrus rootstock to
B - deficiency , suppression subtractive hybridization ( SSH ) and microarray approaches were combined to identify the potential important or novel genes responsive to
B - deficiency . -
pubmed
This case report highlights a rare site of
bleeding following
LMWH use in a haemodialysis
patient . -
pubmed
Cured '
mice were also resistant to
lymphoma re - challenge 80 days later indicating successful generation of immunological memory . -
pubmed
OBJECTIVE : To investigate and analysis the clinical and pathological characteristic of
gastrointestinal stromal tumor (
GIST )
patients , and to clarify the factors that effect on prognosis . -
pubmed
METHODS : The clinical and pathological features and follow - up of
GIST patients who received surgery in Peking Union Medical College Hospital from May 2002 to December 2013 were analyzed retrospectively . -
pubmed
RESULTS : A total of 558
GIST patients were collected , including 284 males and 272 females . -
pubmed
Patients who took targeted therapy with moderate and high risk of
recurrence had a better prognosis compared with not taking the drug . -
pubmed
Tumor size , location , mitosis count and
tumor rupture are independent prognostic factors of
GIST patients . -
pubmed
Although the disease is considered on the verge of disappearance even in tropical countries , its real potential for reemergence - due to new
strains of
Haemophilus ducreyi , underreporting and a lack of widespread use of molecular testing - could be underestimated . -
pubmed
PURPOSE : Exercise - induced skeletal muscle deoxygenation is startling by its absence in early
post - myocardial infarction (
MI )
patients . -
pubmed
We therefore investigated whether aerobic training could enhance the muscle deoxygenation in early post -
MI patients . -
pubmed
We observed limited
GVHD , no TRM , and successful engraftment sufficient to eliminate manifestations of disease in all
patients . -
pubmed
PATIENTS AND METHODS : In this case - control study , 156
inflammatory bowel disease patients ( 110
ulcerative colitis and 46
Crohn ' s disease patients ) and 131 healthy controls were enrolled . -
pubmed
The characteristics of the on- and off - responses in the
human diabetic retina by a " long - duration " multifocal electroretinogram ( mfERG ) paradigm were investigated . -
pubmed
Twenty
type II diabetic patients with no or mild
non - proliferative diabetic retinopathy (
NPDR ) and twenty - one age - matched healthy controls were recruited for " long - duration " mfERG measurements . -
pubmed
The larger amplitude of the on - response component ( N2 ) in the
diabetic patients suggested an imbalance of lateral antagonism , and the lesser percentage change of N2 amplitude in the
diabetic group may indicate an impairment of the cross - talk at the middle retinal level in early stages of
DM . -
pubmed
have made a meaningful contribution to the orthopaedic literature with this study that reports the clinical outcomes of 80
patients who underwent arthroscopic transtendon repair of high - grade , articular - sided partial - thickness
rotator cuff tears . -
pubmed
Nonalcoholic fatty liver disease diagnosed by transient elastography with controlled attenuation parameter in unselected
HIV monoinfected patients . -
pubmed
CONCLUSION :
NAFLD and significant
liver fibrosis diagnosed by transient elastography with
CAP are major comorbidities in unselected
HIV monoinfected persons on antiretroviral therapy , particularly if metabolic conditions and elevated
ALT coexist . -
pubmed
The experience with
captopril is limited in
patients who are
hypertensive after renal transplantation . -
pubmed
We have used
captopril in 58 transplanted
patients with
hypertension . -
pubmed
Captopril in combination with a diuretic and a beta - blocker , reduces blood pressure in
patients with treatment resistant
hypertension following renal transplantation . -
pubmed
OBJECTIVE : To evaluate the performance of low contrast media ( CM ) dose dual - energy computed tomography pulmonary angiography ( CTPA ) with advanced monoenergetic reconstructions in
patients with suspected
pulmonary embolism (
PE ) . -
pubmed
Seven of the 41 ( 17 % )
patients in the low and 5/41 ( 12 % ) in the standard
CM dose group were diagnosed with
PE ( p = 0.32 ) . -
pubmed
No
patient suffered from subsequent
PE or
PE - associated
death during the follow - up period . -
pubmed
METHODS : Specimen were collected from 202
patients who underwent gastric resection for gastric
adenocarcinoma . -
pubmed
Perioperative outcomes in
human immunodeficiency virus - infected patients - the PRO
HIV study . -
pubmed
DISCUSSION :
RMSF occurs through transmission of
Rickettsia rickettsii by an infected tick . -
pubmed
Five
patients had profound
developmental delay and were nonverbal and 4 of them had
epilepsy . -
pubmed
The perioperative courses were uncomplicated except a 2 year - old
girl having an intraoperative
bronchospasm , a 16 year - old girl requiring
flumazenil administration , and 28 year - old
man who was electively intubated with a videolaryngoscope because of airway management concerns . -
pubmed
Bacillus cereus is a Gram - positive spore - forming bacterium causing
food poisoning and serious
opportunistic infections . -
pubmed
They were classified into the
CMV - induced
thrombocytopenia ( 23/29 ) and
CMV - related secondary immune thrombocytopenia (
ITP , 6/29 ) groups . -
pubmed
IVIG was used for 21
patients , and six patients among them showed
recurrence , for whom IVIG or antiviral therapy was used . -
pubmed
All , except one , recurrent or chronic cases belonged to the
CMV - induced
thrombocytopenia group . -
pubmed
Antiviral therapy was used more frequently for the
CMV - induced
thrombocytopenia group ( 8/23 , 34.8 % ) than for the
CMV - related secondary
ITP group ( 0/6 ) ; however , the results were not statistically significant ( P=0.148 ) . -
pubmed
Further ,
CMV - induced
thrombocytopenia is more complex than
CMV - related secondary
ITP . -
pubmed
These
patients were at very low risk for
MACE ( 0.4 % in 30 - days and 2.3 % in one - year ) . -
pubmed
We studied antidiabetic effects and cytoprotective activity of two
lithium salts (
lithium chloride and
lithium carbonate ) on the model of
streptozotocin - induced
diabetes mellitus type 2 in
Wistar rats . -
pubmed
Both
lithium preparations administered to
diabetic animals for 28 days in doses of 10 and 8.9 mg / kg , respectively , attenuated the damaging effect of
streptozotocin . -
pubmed
Exposure to cigarette smoke via respiratory system may induce abnormal alterations of reproductive organs in female
diabetic rats . -
pubmed
Long - Term Effects of Early Life
Seizures on Endogenous Local Network Activity of the
Mouse Neocortex . -
pubmed
Conclusion : Inappropriate doses of antibiotics , a diagnosis of
septic shock and the presence of at least two comorbidities were found to significantly increase the mortality rate of
sepsis patients admitted to an ICU in Indonesia . -
pubmed
Indeed , several
PG species were associated with the severity of
obesity in
mice and
humans . -
pubmed
Maternal dyslipidemia during pregnancy and lactation increases blood pressure and disrupts cardiorespiratory and
glucose hemostasis in female
rat offspring . -
pubmed
In urine samples from men who have sex with men ( n = 400 ) attending a
sexually transmitted disease clinic in Dublin , the prevalence of
M. - pubmed
Efficacy of
Sugammadex in Preventing Skin Test Reaction in a
Patient With Confirmed
Rocuronium Anaphylaxis : A Case Report . -
pubmed
Matching - Adjusted Indirect Comparison of Blinatumomab vs. Inotuzumab Ozogamicin for
Adults with Relapsed / Refractory
Acute Lymphoblastic Leukemia . -
pubmed
INTRODUCTION : In the absence of head - to - head trials , this analysis aimed to provide a fair indirect comparison of the efficacy between
blinatumomab and inotuzumab ozogamicin ( InO ) , two treatments for adult
patients with relapsed or refractory
acute lymphoblastic leukemia ( R / R
ALL ) who received no more than one prior salvage therapy , by adjusting for cross - trial differences . -
pubmed
Patients with 2 + prior salvage therapies from TOWER were excluded because such patients were not included in INO - VATE -
ALL . -
pubmed
The
patient discussed in this case presented with
hoarseness and
dysphagia after receiving epidural anesthesia for childbirth . -
pubmed
The proposed mechanism for this
patient , and in others described in the literature , is puncture of the dura with subsequent egress of cerebrospinal fluid , leading to
intracranial hypotension and traction on cranial nerves . -
pubmed
Unilateral
vocal fold paralysis following spinal anesthesia has been reported in one case series consisting of three
patients , but this represents the first case of bilateral
paralysis . -
pubmed
Patients presenting with idiopathic
vocal fold paralysis , in summary , should be questioned about recent history of epidural or spinal anesthesia , as a positive history may point to transient intrathecal
hypotension as a potential etiology of the
paralysis . -
pubmed
Chelonid Alphaherpesvirus 5 DNA in
Fibropapillomatosis - Affected
Chelonia mydas . -
pubmed
Fibropapillomatosis is a panzootic and
chronic disease among
Chelonia mydas - usually associated with anthropogenic impacts . -
pubmed
This study contributes towards understanding
fibropapillomatosis implications for
C. - pubmed
Patients were included if they had
bipolar cartilage lesions of the knee treated surgically . -
pubmed
Whole - Genome Sequencing to Differentiate
Relapse From Reinfection in Community - Onset Bacteremic
Acinetobacter baumannii Pneumonia . -
pubmed
Community - onset bacteremic
Acinetobacter baumannii pneumonia recurred in 3 of 30 ( 10 % ) patients followed prospectively , all with ongoing hazardous
alcohol intake , 3 - 56 months after initial
pneumonia . -
pubmed
Dupilumab improves health - related quality of life in
patients with
chronic rhinosinusitis with
nasal polyposis . -
pubmed
In a previously reported randomized clinical trial ( NCT01920893 ) , addition of
dupilumab to
mometasone furoate in
patients with
CRSwNP refractory to intranasal
corticosteroids ( INCS ) significantly improved endoscopic , radiographic , and clinical endpoints and
patient - reported outcomes . -
pubmed
RESULTS : Following 16 weeks of treatment , the proportion of
patients with moderate - to - severe
CRSwNP ( VAS & gt;3 - 10 ) decreased from 86.2 % to 21.4 % with
dupilumab and 88.0 % to 84.2 % with placebo . -
pubmed
CONCLUSIONS : In
adults with
CRSwNP refractory to treatment with INCS alone , the addition of dupilumab reduced disease severity , significantly improved HRQoL , and improved productivity . -
pubmed
Bone marrow aspirates form
patients with
multiple myeloma were obtained and lymphocytes were isolated using density gradient centrifugation . -
pubmed
CONCLUSION : Magnetic stents cause similar morbidity for
patients compared with standard stents removed by flexible cystoscopy ; they are associated with less
pain at removal and are cost saving . -
pubmed
In order to examine the efficacy of
human cell based therapy in
anthracycline - induced
injury , we characterized a
mouse model using an immune compromised
strain of
mice capable of accepting
human cells . -
pubmed
Gastrointestinal and
hepatic injury occurred at 4 mg / kg and 1.5 mg / kg dosing while
mice receiving 0.5 mg / kg weekly only displayed
hepatic damage . -
pubmed
Histological assessment shows no overt
cardiomyocyte injury but livers from
mice treated with
doxorubicin show marked hepatic plate
atrophy with intracytoplasmic and canalicular
cholestasis , rare pericentral hepatocellular
necrosis and significant zone 3
iron accumulation , likely an indication of
metabolic injury due to
doxorubicin toxicity . -
pubmed
Conclusions : Immune compromised
mice are sensitive to
doxorubicin therapy resulting in systemic complications in addition to
cardiovascular toxicity . -
pubmed
Anthracycline - induced
cardiotoxicity is observed at very low doses in
NOD.Cg - Prkdcscid Il2rgtm1Wjl / SzJ mice . -
pubmed
Ultimately , the management of advanced
BTC is likely to become molecularly selected in the near future with the hope of finally improving the bleak prognosis of
patients with this disease . -
pubmed
A second generation of anti - complement agents is currently under investigation , representing future promising therapeutic strategies for
patients affected by
PNH . -
pubmed
edodes stress - sensitive
strain YS55 via the Agrobacterium - mediated transformation method . -
pubmed
METHODS : A total of 2,199
MS patients ( female / male ratio of 1,651/548 ) underwent structural MRI imaging on either a 1.5 - T or 3 - T scanner . -
pubmed
This study aimed to investigate the changes in
anxiety ,
depression , the ratios of T helper cells 17 ( Th17 ) and regulatory T cells ( Tregs ) , and
inflammation levels in
patients with pulmonary nodules . -
pubmed
The
patients were divided into two groups according to the scale scores : 62 cases in a non - anxiety and
non - depression (
NAD ) group and 41 cases in an
anxiety and/or
depression (
AD ) group . -
pubmed
The proportion of
anxiety and/or
depression in female
patients with pulmonary nodules was higher than that in males ( P<0.05 ) . -
pubmed
CONCLUSIONS :
Patients with pulmonary nodules are prone to varying degrees of
anxiety and
depression , which leads to
immune dysfunction and
low - grade inflammation . -
pubmed
BACKGROUND : Coronaviruses ( CoVs ) were long thought to only cause mild
respiratory and gastrointestinal symptoms in
humans but outbreaks of
Middle East Respiratory Syndrome ( MERS )- CoV ,
Severe Acute Respiratory Syndrome ( SARS )- CoV-1 , and the recently identified
SARS - CoV-2 have cemented their zoonotic potential and their capacity to cause serious morbidity and mortality , with case fatality rates ranging from 4 to 35 % . -
pubmed
However , we did observe a protective effect in an organotypic respiratory cell culture system by exposing pre - treated respiratory epithelium to droplets of
HCoV-229E , imitating a natural
infection . -
pubmed
The observed virucidal activity of Echinaforce was not restricted to
common cold coronaviruses , as both
SARS - CoV-1 and
MERS - CoVs were inactivated at comparable concentrations . -
pubmed
OBJECTIVE : To evaluate
sleep disorders and chronotype in
patients with drug resistant focal and generalised
epilepsy compared to healthy controls . -
pubmed
METHODS : Sixty four
patients with focal and six with generalised ,
drug resistant epilepsy were included and compared to 70 age- and gender - matched healthy controls . -
pubmed
The impact of
epilepsy on quality of life was also documented in
patients . -
pubmed
Self - reported
confusional arousals and probable
REM sleep behaviour disorder (
RBD ) were more frequent in
patients ( 30.4 % vs. 8.6 % , p = 0.036 and 10.6 % vs. 1.4 % , p = 0.030 , respectively ) . -
pubmed
A higher risk for possible
sleep apnea was identified in
patients ( 22.9 % vs. 5.7 % , p = 0.042 ) , whereas Epworth Sleepiness Score was normal in both groups ( p = 1 ) . -
pubmed
CONCLUSION : Self - reported
confusional arousals , probable
RBD and a high risk for
sleep apnea occurred significantly more often in
patients with
drug resistant epilepsy . -
pubmed
MOTIVATION : Beside socio - economic issues , coronavirus pandemic COVID-19 , the
infectious disease caused by the newly discovered coronavirus
SARS - CoV-2 , has caused a deep impact in the scientific community , that has considerably increased its effort to discover the
infection strategies of the new virus . -
pubmed
Despite the lack of shared human proteins in these virus - host networks , and the low number of preserved virus - host interactions , the consensus alignment revealed aligned human proteins that share a function related to
viral infection , as well as
human proteins of high functional similarity that interact with
SARS - CoV-1 and
SARS - CoV-2 proteins , whose alignment would preserve these virus - host interactions . -
pubmed
We are witnessing an unparalleled pandemic caused by the novel
Severe Acute Respiratory Syndrome Coronavirus 2 (
SARS - CoV-2 ) associated with
coronavirus disease 2019 ( COVID-19 ) . -
pubmed
Thus , we characterize the
AT- and CG - rich DNA pattern for the genus Rhodnius , and we suggest that the pattern of CG - rich heterochromatin in the autosomes of these vectors evolved independently in pallescens , pictipes ,
and prolixus groups . -
pubmed
Potential effect of tropical fruits
Phyllanthus emblica L. for the prevention and management of
type 2 diabetic complications : a systematic review of recent advances . -
pubmed
Taken together ,
Phyllanthus emblica may be an ideal fruit for controlling
diabetic complications . -
pubmed
This review highlights the latest findings of the role of
Phyllanthus emblica in
anti - diabetes and its complications , especially clarifies the molecular mechanism of the chemical components related to this effect , and prospects some existing problems and future research directions . -
pubmed
Objective :
Patients with
cancer pain are highly dependent on
morphine analgesia , but studies have shown a negative correlation between
morphine demand and
patient outcomes . -
pubmed
Finally , the
LLC murine lung adenocarcinoma cell line were used to establish a
murine lung cancer model , and the effects of
M3 G on
tumor growth and
metastasis were determined . -
pubmed
Cellular energy metabolism , trans - plasma and trans - mitochondrial membrane potentials , and pH gradients in
mouse neuroblastoma . -
pubmed
coli enterotoxin released from a
porcine E. coli strain into culture medium . -
pubmed
The hematopoiesis of athymic - asplenic ( lasat )
mice was compared with that of normal , asplenic , and athymic littermates with the same
strain background . -
pubmed
Erythrocyte blood volume , number and survival time were normal when related to the
body weight of the
animals . -
pubmed
When
diabetic subjects with
triglyceride levels over 400 mg / dl were selected for study , most were found to have an independent familial form of
hypertriglyceridemia . -
pubmed
In a group of 156
patients with
arteriopathy , 87 ( aged between 10 and 40 years ) exhibited
thromboangiitis obliterans and 9 ( aged 40 to 50 years )
arteritis of middle age , according to Van der Stricht 's classification . -
pubmed
Chemotherapy of a
human malignant melanoma transplanted in the
nude mouse . -
pubmed
The effects of single agent therapy with
1 -(- chloroethyl )- 3 - cyclohexyl-1 - nitrosourea ,
5 - fluorouracil , and
5 -( 3,3 - dimethyl-1 - triazeno )- imidazole-4 - carboxamide on a
human malignant melanoma transplanted and passed serially in thymusless
nude mouse were studied . -
pubmed
The results resemble those reported from clinical practice in
patients with disseminated
malignant melanomas treated with the same agents . -
pubmed
This suggests that the pattern of drug susceptibility is preserved after transplantation of
tumors in the
nude mouse . -
pubmed
The
human tumor -
nude mouse system is advocated as a new in vivo model for determination of individual
tumor response to chemotherapeutic agents , and its potential as a model for the proving of new chemotherapeutic agents is suggested . -
pubmed
Detection of papillomaviral - like DNA sequences in premalignant and malignant
perineal lesions of
sheep . -
pubmed
Small
hyperkeratotic and
ulcerated lesions and clinical
cancers were isolated from the perineal region of
sheep and examined for evidence of
papillomavirus infection by various criteria including gross morphology , histology , immunohistochemistry and DNA hybridisation . -
pubmed
This finding suggests that a papillomavirus is associated with the development of
squamous cell carcinomas of the perineum of
sheep . -
pubmed
Angioplasty in the
patient with an evolving
myocardial infarction : with and without surgical backup . -
pubmed
Tuberculosis could have been diagnosed without mediastinoscopy only in 3
patients : 2 had positive bronchial cultures and 1 simultaneous cervical lymph node
tuberculosis . -
pubmed
An outbreak of
human and canine
blastomycosis . -
pubmed
In the summer and fall of 1988 , three
humans and one
dog in a lakeshore community in northern Wisconsin were found to have
blastomycosis on the basis of the results of cultures and histologic studies ; the
infection was also suspected in one
human and four
dogs on the basis of clinical data . -
pubmed
The result of this study further confirm the common occurrence of self - limited and subclinical
infection with B. dermatitidis and suggest that excavation in an area endemic for
B. - pubmed
dermatitidis is a risk factor for
human and canine
infection . -
pubmed
Development of EEG background activity in
children with
benign partial epilepsy . -
pubmed
We investigated the developmental features of the EEG - background activity of the 30
patients with
benign childhood epilepsy . -
pubmed
In the
patients with benign childhood
epilepsy , the development of the EEG - background activity came to be stagnant from 6 years old or so , and after 10 years old it developed again and approached to that of the normal
children . -
pubmed
It is suspected that the EEG background activity of
children with
benign partial epilepsy shows a special development . -
pubmed
The excitatory
amino acid antagonists
GDEE and
MK-801 [
( + ) - 5 - methyl-10,11 - dihydro-5H - dibenzo [ a , d ] cyclo - hepten-5,10 imine ] were tested as anticonvulsants for
strychnine - induced
seizures in 3AP inferior olive - lesioned and control
rats . -
pubmed
Neither drug effected
seizures in control
rats , however , both
GDEE and
MK-801 produced a leftward shift in the
strychnine -
seizure dose - response curve in 3AP inferior olive - lesioned
rats . -
pubmed
The frequency of
bilateral physiolysis colli femoris was evaluated in 62
patients . -
pubmed
We recommend bilateral pinning at first admission in all
patients with a
slipped capital femoral epiphysis . -
pubmed
Mediastinal lymph node dissection in
bronchial carcinoma patients means an additional procedure to the
tumor resection . -
pubmed
In this report the authors describe a
patient who developed
anterior wall myocardial infarction secondary to a blunt
chest trauma . -
pubmed
The ocular examinations and hospital records of 64
patients with Hollenhorst plaques were retrospectively reviewed to document any associated
visual defects and to determine if carotid endarterectomy prevented the occurrence of new plaques or symptoms . -
pubmed
Twenty - eight carotid endarterectomies were performed ipsilateral to a Hollenhorst
plaque : 24
patients had no symptoms ; four
patients developed new ipsilateral asymptomatic
Hollenhorst plaques at 1 to 50 months after operation . -
pubmed
Eight eyes in
patients with no symptoms had multiple Hollenhorst plaques , one of which was associated with a subsequent
stroke . -
pubmed
An analysis of factors associated with
ectopic pregnancy in a
human in vitro fertilization program . -
pubmed
Antiulcerogenic activities of three plant drugs were studied against
aspirin - induced
gastric ulcers in
rats . -
pubmed
Solanum nigrum ( aerial parts ) powder and its methanolic extract decreased the
ulcer index significantly . -
pubmed
Brassica oleracea ( leaf ) powder did not affect the
ulcer index significantly but its aqueous extract lowered the index and increased
hexosamine levels , suggesting gastric mucosal protection . -
pubmed
A middle - aged
woman presenting with
multiple cranial neuropathies ,
hemiparesis , and
CSF pleocytosis had
tuberculous infection of the cranial dura mater at autopsy . -
pubmed
Valpromide increases the plasma concentrations of
amitriptyline and its metabolite
nortriptyline in
depressive patients . -
pubmed
The effects of
valpromide on
amitriptyline (
AMT ) and
nortriptyline (
NT ) plasma levels were examined in 20
depressed inpatients . -
pubmed
[ Is
cataract surgery with posterior chamber lens in
patients with
senile maculopathy worthwhile ? ] -
pubmed
To determine if PVAs initiated in
patients with spontaneous sustained
ventricular tachycardia or
fibrillation differ from those which are clearly a nonspecific response in structurally normal hearts , the initiation , characteristics , and relationship to ventricular repolarization of PVAs greater than five beats in duration were evaluated in 32
patients without
structural heart disease and in 36
patients with spontaneous sustained
ventricular arrhythmias more than 9 days after
myocardial infarction . -
pubmed
In a comparison with
patients who completed the same steps ( defined by the basic drive cycle length and number of extrastimuli ) in the stimulation protocol , there was no difference in the cumulative risk of initiation of a PVA between the
patients with and those without
heart disease at any step . -
pubmed
The morphology of the apical surface of
rabbit retinal
pigment epithelium was studied by scanning
electron microscopy from the first minute to several hours after making small nonrhegmatogenous
retinal detachments ( blebs ) . -
pubmed
[ Immunomorphological changes in the
tumors and regional lymph nodes in
breast cancer patients treated preoperatively with radioactive gold ] . -
pubmed
Aspergillus fumigatus infection in the
scaly weaver (
Sporopipes squamifrons ) . -
pubmed
Morphometry of
right ventricular hypertrophy induced by
myocardial infarction in the
rat . -
pubmed
The growth response of the right ventricle was studied in
rats following ligation of the left coronary artery , which produced
infarcts comprising approximately 40 % of the left ventricle . -
pubmed
[ Plasma
catecholamine changes in
patients with acute
myocardial infarction and their clinical significance ] . -
pubmed
Angiotensin II infusions did not increase plasma
catechol - amines , and lowering of
angiotensin II by
captopril treatment in
patients with severe
hypertension or
congestive heart failure failed to alter plasma
adrenaline or nor -
adrenaline levels . -
pubmed
High - dose
Ara - C for remission induction and consolidation of previously untreated
adults with
ALL or
lymphoblastic lymphoma . -
pubmed
Thirty - two
patients with untreated
ALL ( n = 26 ) or
lymphoblastic lymphoma ( n = 6 ) between 17 and 65 years of age were treated with a short remission induction course with
VP16 - 213 ,
amsacrine , intermediate dose
Ara - C for 6 days ,
prednisone and intrathecal
methotrexate , followed by a consolidation course with
vincristine ,
amsacrine , high dose
Ara - C for 4 days ,
prednisone and intrathecal
methotrexate . -
pubmed
Ten of 13
patients with
T - ALL or
lymphoma , six of eight
patients with pre - B or common
ALL , and seven of 11
patients with
B - ALL or
Burkitt ' s lymphoma achieved a complete remission . -
pubmed
Long - term survival for
patients with
B or T - ALL was approximately 60 % , compared with 15 % for those with common or
pre B - ALL . -
pubmed
Our regimen may be sufficient for
patients with
T or B - ALL . -
pubmed
[ The clinical picture , diagnosis and rationale for the combined treatment of
patients with an
intracranial hypertension syndrome of
nontumor origin . -
pubmed
To evaluate the effect of hyperbaric
oxygen therapy on chronic
wound healing , 16 otherwise healthy
patients who had nondiabetic ,
chronic leg ulcers with no large vessel disease were included in a double - blind study . -
pubmed
The
wound area was copied onto transparent film covering the
wound and then measured using only one matching
wound from each
patient . -
pubmed
Monkey cerebral arterial relaxation caused by hypercapnic
acidosis and hypertonic
bicarbonate . -
pubmed
Stomach function and secretions are altered significantly in
patients with
cirrhosis , both with or without portal
hypertension . -
pubmed
In order to correlate morphologic parameters and functional assessment , a prospective study was performed on 45
patients after surgical treatment of intraarticular calcaneal
fractures using standard radiographic and computed tomographic scores , clinical evaluation , and gait analysis ( dynamic pedography ) . -
pubmed
The detection and typing analysis of
human papillomavirus (
HPV ) were carried out by means of BIOHIT in situ
HPV DNA hybridization screening and typing kits in
condyloma tissues of patients with
genital condyloma acuminatum , in cytological smears of their asymptomatic female consorts , and in female patients with
vulval condyloma acuminatum . " -
pubmed
Low"-risk
HPV 6 and
HPV 11 were demonstrated most frequently in the
condyloma tissues of the male patients . -
pubmed
Medium " and " high"-risk
HPV 18 , 31 and 33 types ( frequently associated with
high - grade dysplastic lesions and
carcinomas ) were demonstrated more frequently in female
condylomas than in male . -
pubmed
These three
HPV types were identified in both tissues in a female patient with
condyloma acuminatum and
carcinoma epidermoids cornescens . -
pubmed
Twelve
patients demonstrated a
vasospasm on 22 angiographies . -
pubmed
There were no survivors among an estimated 398
patients who had
lung injury and either required more than 4 hours of vasopressor support or had sustained
hepatic and renal failure . -
pubmed
Through the use of these factors , an accurate prediction of
death could have been made in the first 4 days of mechanical ventilation for more than half of the
patients who did not survive . -
pubmed
CONCLUSION : Of the
patients who required mechanical ventilation after bone marrow transplantation , no one survived with
lung injury combined with either hemodynamic instability or
hepatic and renal failure . -
pubmed
Some of the most important clinical applications involve the early detection of iris new vessels ,
cataract management in diabetic
patients , and monitoring of
iris tumors . -
pubmed
SCH 47112 , a novel
staurosporine derivative , inhibits
12 - O - tetradecanoylphorbol-13 - acetate - induced
inflammation and
epidermal hyperplasia in hairless
mouse skin . -
pubmed
METHODS : We observed the microcirculation in nailfold of 30 normal pregnant
women and 76 cases of
PIH . -
pubmed
It has been shown previously that
tobramycin encapsulated in fluid liposomes ( composed of
dipalmitoylphosphatidylcholine (
DPPC ) and
dimyristoylphosphatidylglycerol (
DMPG ) ) eradicated mucoid
Pseudomonas aeruginosa in an animal model of
chronic pulmonary infection . -
pubmed
Six hours and 16 h after treatment , the maximal reduction of growth between
strains treated with liposome - encapsulated
tobramycin and free
tobramycin was 84 , 129 , 166 , 10(5 ) and 10(4 ) times respectively for
P. - pubmed
OBJECTIVE : To review our experience of surgical staging for residual masses after chemotherapy in
patients with
nonseminomatous germ cell tumour (
NSGCT ) and positive
tumour markers . -
pubmed
PATIENTS AND METHODS : Of 107
patients with
metastatic NSGCTs treated surgically after chemotherapy from 1978 to 1995 , 30 ( median age 30.5 years , range 20 - 52 ) had positive
tumour markers . -
pubmed
These
patients were reviewed and the outcome compared with 77
patients who had normal
tumour marker values . -
pubmed
RESULTS : Of the 77
patients with negative markers undergoing surgical / pathological staging , 71 ( 92 % ) became continuously disease - free , including 37 of 50 ( 74 % ) with viable
NSGCT in excised specimens . -
pubmed
CONCLUSION : Although the outcome after surgery is better in
patients with negative
tumour markers , it is clear that surgery is curative for
patients with localized chemotherapy - resistant masses . -
pubmed
Thus , in frail elderly
patients , there are contradictory relationships between
DHEA - S and neuropsychiatric measures of
frailty (
cognitive impairment , disability ,
insomnia , and number of
pain sites ) , and there may also be gender differences in these relationships . -
pubmed
Liver transplantation for endstage
hepatitis C cirrhosis in a
patient with
primary hypogammaglobulinaemia . -
pubmed
Liver transplantation was performed in a
patient with
primary hypogammaglobulinaemia ,
chronic hepatitis C and
hepatic failure . -
pubmed
Liver biopsies demonstrated the
recurrence of
HCV . -
pubmed
14 months after the transplantation the patient developed severe
diarrhoea caused by
Cryptosporidium parvum . -
pubmed
The present case report illustrates the difficulties associated with organ transplantation in
patients with
primary hypogammaglobulinaemia . -
pubmed
Early dialysis in
heart insufficiency of
patients with
chronic renal failure . -
pubmed
In
patients with severe
heart failure life expectancy is short , the quality of life is affected , and the service costs are very high . -
pubmed
In our study we followed
patients suffering from class - IV
cardiac failure concomitant with
chronic renal failure . -
pubmed
Here we describe a case of
gastrointestinal autonomic nerve tumor (
GANT ) arosen in a
patient with
von Recklinghausen ' s disease . -
pubmed
Prevalence of verotoxin - producing
Escherichia coli (
VTEC ) in
bovine coli mastitis and their antibiotic resistance patterns . -
pubmed
Between December 1996 and October 1997 , milk samples from a total of 145
cows with coli
mastitis were screened for the presence of verotoxin - producing
E. - pubmed
The four isolated
strains proved to be verotoxin ( VT ) 1- , VT2- or
VT1- and VT2 - positive . -
pubmed
OBJECTIVE : This is a report of endovascular treatment of a case of
type B thoracoabdominal aortic dissection in a
patient with progressive
dyspnea ,
dorsolumbar pain , and expanding aortic diameter over a 1 - year period . -
pubmed
The
camptothecin derivatives
topotecan and
irinotecan represent new weapons in our arsenal for battling
human cancer . -
pubmed
The endothelium of spontaneously
hypertensive rats ( SHR ) released 35 % less
NO ( 580 + /- 30 nmol l(-1 ) ) than that of normotensive
rats ( 920 + /- 50 nmol l(-1 ) ) , due to the higher production of
O2- in SHR
rats . -
pubmed
Ischemia ( lower limb of
rabbit ) caused a significant increase of
NO peaking at 15 min and decreasing thereafter , also due to
O2- production . -
pubmed
A
girl with a history of
insulin - dependent diabetes mellitus since 5.5 years , and
Hashimoto ' s thyroiditis since 12 years , developed episodes of severe
hypoglycemia from the age of 12 years . -
pubmed
Effect of
phenobarbitone administration to pregnant
rats on
anxiety in offsprings . -
pubmed
The unusual site of
infection may probably be related to the use of contaminated needless and syringes for
HIV drug injection . -
pubmed
METHODS : Five
patients with gastric
GIST ( 36 - 85 years old ) underwent subserosal excision with subsequent B - II resection ( 1x ) , full - thickness partial gastric resection ( 2x ) , gastrotomy with submucosal excision ( 1x ) , or gastrectomy for
carcinoma with an incidental finding of a
leiomyoma ( 1x ) . -
pubmed
To date ,
fluorouracil plus
folinic acid represents the standard therapy in
CRC for the adjuvant treatment of
patients at high risk for
relapse and for the first - line treatment of metastatic
disease . -
pubmed
Future research is focused on enabling clinicians to individualise treatment strategies in
patients with
CRC , so as to improve clinical outcomes and reduce
drug toxicity . -
pubmed
Mortality among
patients with
breast cancer (
BC ) is mainly caused by metastasis . -
pubmed
We distinguished the mRNA levels in circulation between
BC patients and healthy controls with reference to a BC - derived cell line ,
SK - BR-3 . -
pubmed
We prospectively analyzed peripheral blood samples from 33
BC patients and 26 healthy controls . -
pubmed
OBJECTIVE : The objective of the study was to study gall bladder volume in fasting and 45 minutes post - prandial , by real time ultrasound in healthy controls and
diabetic patients with and without
autonomic neuropathy and to compare them . -
pubmed
METHOD : Age , Sex and
body mass index (
BMI ) matched 50 healthy subjects and 10
patients with
insulin dependent diabetes mellitus and 40
patients with
noninsulin dependent diabetes mellitus were evaluated according to National
diabetes Data Group of National Institute of Health ( 1979 ) criteria : 1 . -
pubmed
Patients of
diabetes mellitus had statistically significant larger fasting gall bladder volumes and these values were highly significant amongst
patients with
autonomic neuropathy . -
pubmed
CONCLUSIONS : We therefore conclude that impaired gall bladder contraction was found amongst
patients of
diabetes mellitus with
autonomic neuropathy . -
pubmed
Vascular invasion in
squamous cell carcinomas of
human oral mucosa . -
pubmed
The process of vascular invasion of
human oral squamous cell carcinomas was histologically and immunohistochemically studied in surgical and autopsy specimens . -
pubmed
These findings showed that mechanical pressure has an important role in the vascular invasion of
human oral squamous cell carcinoma . -
pubmed
After 20 months , a group of
HFS rats were switched to the LFCC diet ( HFS / LFCC ) for a period of 2 months . -
pubmed
In acute
LMCA obstruction , lead aVR ST segment elevation also contributes to predicting a
patient 's clinical outcome . -
pubmed
Cell - mediated immunity to
tumors induced by Ab2 was investigated by a delayed - type
hypersensitivity response and the
mouse T - cell proliferation assay . -
pubmed
The glycoprotein was purified from normal plasma and individual
chronic myeloid leukemia (
CML )
patients ' plasma by low - pressure chromatography . -
pubmed
At 1 year of age ,
HCII - deficient animals were grossly indistinguishable from their wild - type littermates in weight and survival , and they did not appear to have spontaneous
thrombosis or other morphologic abnormalities . -
pubmed
In comparison with wild - type
animals , however , they demonstrated a significantly shorter time to
thrombotic occlusion of the carotid artery after photochemically induced
endothelial cell injury . -
pubmed
SUBJECTS : Three hundred seventy - four
chronic pain patients ( 300 aged 13 to 59 years ; 74 aged 60 to 89 years ) assessed at an outpatient , multidisciplinary
pain management centre . -
pubmed
METHODS :
Patients completed measures of demographic and descriptive information ,
pain intensity ( box rating scale ) , perceived disability ( modified
Pain Disability Index ) and affective distress ( Symptom Checklist-90 Revised ) before multidisciplinary treatment . -
pubmed
We present the case of a 16 - day - old infant with
tinea capitis caused by
Microsporum canis and effectively treated with topical
bifonazole 1 % . -
pubmed
PURPOSE : We have simplified the treatment of
gestational trophoblastic disease (
GTD ) in order to reduce the number of
patients exposed to potentially carcinogenic chemotherapy . -
pubmed
PATIENTS AND METHODS : Between 1992 and 2000 , 485
women with
GTD were commenced on
MTX /
FA at Charing Cross Hospital , London , United Kingdom . -
pubmed
In the present study , we evaluated the speed of cognitive processing in
patients with
PD without
bradykinesia as a variable . -
pubmed
This case report presents a
patient who developed a large overhanging
bleb following antimetabolite trabeculectomy surgery 6 years prior . -
pubmed
Adjuvant intraperitoneal chemotherapy with
cisplatinum ,
mitoxantrone ,
5 - fluorouracil , and
calcium folinate in
patients with
gastric cancer : a phase II study . -
pubmed
Clinical studies have revealed that approximately two thirds of the
patients seek treatment for early
recurrence within the abdominal cavity . -
pubmed
The aim of this phase II study was to evaluate the
toxicity , feasibility , and efficacy of adjuvant intraperitoneal chemotherapy ( IPCT ) with
cisplatin ,
mitoxantrone ,
5 - fluorouracil (
5 - FU ) , and
folinic acid in
patients with
stage II - III gastric cancer . -
pubmed
The major nonhematologic
toxicity from IPCT was grade I - III
nausea and/or
vomiting experienced by 27
patients ( 69.2 % ) . -
pubmed
Twenty - four ( 61.5 % )
patients reported
abdominal discomfort . -
pubmed
Its association with the
infection caused by a virus of the Epstein - Barr family ,
human herpesvirus 8 (
HHV-8 ) , has been recently demonstrated . -
pubmed
In this article we discuss the unusual presentation of a solitary manifestation of
Kaposi ' s sarcoma on the penis of a 53 - year - old
HIV - negative patient . -
pubmed
The case is interesting for its unusual site of presentation , the young age of onset , the association with
HHV-8 infection , the
HIV - negative serology , and the benign course of the disease . -
pubmed
[ Effect of
hyperthermia on the red - cell immune function of
rats and its teratogenicity on developing embryos ] . -
pubmed
Glucose utilization and
lactate production by leucocytes of
patients with
diabetes mellitus . -
pubmed
[
Psychoses and
psychotic states in
children ] . -
pubmed
The
toxicity of the natural insecticide
spinosad was assessed against
Daphnia pulex ( Leydig ) using a demographic approach . -
pubmed
Theanine , a naturally occurring non - proteinic
amino acid found in
tea leaves , has demonstrated wide - ranging physiological activity , from lowering blood pressure to enhancing the anti -
tumor activity of chemotherapeutic drugs . -
pubmed
Naamine G ( 3 ) exhibited strong antifungal activity against the phytopathogenic fungus
Cladosporium herbarum and also showed mild
cytotoxicity against
mouse lymphoma (
L5178Y ) and
human cervix
carcinoma (
HeLa ) cell lines . -
pubmed
Rabies cell culture vaccines reconstituted and stored at 4 degrees C for 1 year prior to use protect
mice against
rabies virus . -
pubmed
Sheep and suckling
mouse brain
rabies vaccines used in developing countries are being replaced by expensive inactivated - virus cell culture vaccines . -
pubmed
Our laboratory has performed studies among pregnant
rat and
sheep in which we simulate drought conditions via maternal
dehydration and famine conditions via nutrient restriction . -
pubmed
For the first time , a live genetically modified
bacterial strain has been approved by Dutch authorities as a therapeutic agent for experimental therapy of
intestinal bowel disease (
IBD ) in
humans . -
pubmed
OBJECTIVE : The authors evaluated concordance rates among three electrophysiological measures in
patients with
schizophrenia , nonschizophrenic first - degree relatives of
schizophrenia patients , and healthy comparison subjects . -
pubmed
Data for all three paradigms were available for 81
patients with
schizophrenia , 25 parents of
patients with
schizophrenia , and 60 healthy comparison subjects . -
pubmed
Mechanisms of
human diseases have been elucidated along with the progress of the
Human Genome Project , which has enabled accurate genetic testing towards personalized medicine . -
pubmed
METHODS : A series of 71
females who had undergone transanal repair of low isolated
rectocele was retrospectively reviewed . -
pubmed
RESULTS : Twenty - nine of 71
patients had isolated low
rectocele recurrence , and 6 had a
rectocele recurrence associated to an
enterocele occurrence . -
pubmed
Mounting evidence exists that the activation of proto - oncogene by somatic mutation plays an important roles in the development of
human cancers . -
pubmed
However , only marginal anti -
tumor efficacy of the
adenoviral Sant7 was observed . -
pubmed
Enterovirus 71 (
EV71 ) is a highly infectious major causative agent of
hand , foot , and mouth disease (
HFMD ) which could lead to severe
neurological complications . -
pubmed
PATIENTS AND METHODS : Thirty - five
patients , with histologically verified
CIS of the urinary bladder , were included in the study . -
pubmed
This has been driven by the purportedly beneficial effects of co -
infection on clinical pathology and the recognition of
Plasmodium vivax as a public health problem in its own right . -
pubmed
Somatic
pain sensitivity during formation and healing of
acetic acid - induced
gastric ulcers in conscious
rats . -
pubmed
BACKGROUND AND PURPOSE : To investigate the feasibility and potential benefits of combining electron and photon intensity modulated radiotherapy ( IMRT ) for
patients with
malignant pleural mesothelioma (
MPM ) . -
pubmed
CONCLUSIONS : This study showed that IMRT or IMRT+e is a viable treatment modality for
MPM patients . -
pubmed
The possible implications of these findings for menopausal hormone therapy in
women and
breast cancer risk are discussed . -
pubmed
Operant conditioning of H - reflex can correct a
locomotor abnormality after
spinal cord injury in
rats . -
pubmed
These results suggest that appropriately selected reflex conditioning protocols might improve function in
people with partial
spinal cord injuries . -
pubmed
The absence of intervening sequences in 23S rRNA genes of
Campylobacter coli isolates from
Turkeys is a unique attribute of a cluster of related
strains which also lack resistance to
erythromycin . -
pubmed
In this study , 104
strains of
Campylobacter coli from turkeys , representing 27 different multilocus sequence typing - based sequence types ( STs ) , were characterized in terms of IVS content and
erythromycin susceptibility . -
pubmed
The STs of the latter
strains belonged to an unusual cluster of
C. - pubmed
coli from
turkeys is characteristic of a unique clonal group of
erythromycin - susceptible
strains and that IVS can be acquired by these
strains via natural transformation to
erythromycin resistance . -
pubmed
We combined analysis of mutations causing
human Mendelian diseases , of
human -
chimpanzee divergence , and of systematic data on
human genetic variation and found that ~20 % of new missense mutations in
humans result in a loss of function , whereas ~27 % are effectively neutral . -
pubmed
Patients who had advanced , previously untreated diffuse aggressive
lymphomas (
IWF E - H ) and an International Prognostic Index of intermediate to high risk were eligible . -
pubmed
Six
patients have developed
AML or
MDS . -
pubmed
Between April 1996 and October 2004 , 184
patients with
germ cell tumor were treated at Indiana University with salvage high - dose chemotherapy ( HDCT ) with autologous peripheral blood stem cell transplant . -
pubmed
One additional
patient who relapsed after HDCT and was treated with third line chemotherapy followed by two surgical resections of
choriocarcinoma is currently alive NED at +90 months from HDCT . -
pubmed
Long - term disease - free survival and potential cure is possible with HDCT in
choriocarcinoma patients that progressed after standard
cisplatin combination therapy . -
pubmed
Knowledge of
HIV and
AIDS among tertiary students in Bangladesh . -
pubmed
Plasmapheresis and pregnancy outcome in
patients with
antiphospholipid syndrome . -
pubmed
OBJECTIVE : To assess plasmapheresis with low dose
prednisone on obstetric and neonatal outcomes among unsuccessfully treated pregnant
women with documented
antiphospholipid syndrome (
APS ) . -
pubmed
Plasmapheresis may be used to treat pregnant
women with documented
APS when first lines (
aspirin and/or
heparin ) fail to prevent pregnancy loss . -
pubmed
Patients were then divided into 2 other groups according to
pain onset ( MSCT performed within the first 12 h of
pain onset and MSCT performed thereafter ) . -
pubmed
CONCLUSION : MSCT should be performed even in
patients in whom the clinical suspicion of
appendicitis is low . -
pubmed
MSCT is effective in
patients with early - stage
appendicitis . -
pubmed
In this study , we investigated the quantitative and qualitative changes in NKT cells in bone marrow ( BM ) mononuclear cells of
AA patients in response to in vitro stimulation with
alpha - galactosylceramide . -
pubmed
Compared to healthy controls , BM from
AA patients had reduced fraction of NKT cells , which possessed a decreased potential to expand in vitro in response to
alpha - galactosylceramide stimulation , producing more
IFNgamma + NKT1 cells . -
pubmed
RESULTS : Overall , among the 51
patients with intended complete tumour removal , iMRI revealed definite
tumour remnants or suspicious findings in 13
patients ( 25.5 % ) , leading to an extended resection and allowing completion of the resection in 10
patients . -
pubmed
The protective effect of fish
n-3 fatty acids on
cerebral ischemia in
rat prefrontal cortex . -
pubmed
Cerebral ischemia and reperfusion was produced in
rats either on a standard diet ( Group B ) or a standard diet plus fish
n-3 EFA for 14 days ( Group C ) . -
pubmed
There were no differences between groups in 4 - year and 8 - year survival rates , with 77.2 % and 61.8 % , respectively , in
patients with
DSWI compared with 78.0 % and 67.5 % in
patients without DSWI ( P = 0.16 ) . -
pubmed
Acetic acid induced
ulceration in
rats is not affected by infection with
Hymenolepis diminuta . -
pubmed
Analysis of rodent models of
inflammatory bowel disease , airways hyper - reactivity ,
diabetes , and
multiple sclerosis has shown that
infection with
helminth parasites can significantly reduce the severity of the disease . -
pubmed
Here , we assessed whether
rats infected with the tapeworm
Hymenolepis diminuta were protected from
gastric ulceration induced by the serosal application of
acetic acid . -
pubmed
All
rats gavaged with infective cysticercoids harbored adult worms when assessed 6 wk later , and
acetic acid evoked the expected
gastric ulceration . -
pubmed
However ,
infection with
H. - pubmed
While the data do not dismiss the possibility that
infection with other
helminths could be anti - ulcerogenic , they illustrate that '
helminth therapy ' for
inflammatory disease is likely to be both disease- and helminth - specific . -
pubmed
All
patients with
anemia secondary to
CKD should be treated and evaluated for possible treatment , irrespective of underlying disease , associated comorbidity or possibility of kidney replacement therapy . -
pubmed
In all cases and for all ESAs , the subcutaneous route is the recommended route of administration for
patients with
CKD ( Strength of Recommendation C ) . -
pubmed
There is insufficient evidence in
patients with
CKD to justify routine use of coadjuvant treatments . -
pubmed
Amlodipine reduces predicted risk of
coronary heart disease in high - risk
patients with
hypertension in Spain ( The CORONARIA Study ) . -
pubmed
We evaluated the efficacy and safety of
amlodipine besylate alone or in combination with other antihypertensive agents in high - risk
hypertensive patients in Spanish primary care . -
pubmed
In this 1 - year , open - label , prospective cohort study , 7468
patients were treated with
amlodipine 5 - 10 mg as a monotherapy or as an add - on therapy to attain blood pressure control ( target of & lt ; 140/90 mmHg or , in
patients with conditions such as
diabetes or
chronic kidney disease , & lt ; 130/85 mmHg ) . -
pubmed
Frontal bandeau reconstruction with a fibula flap in a
patient with
Freeman - Sheldon syndrome . -
pubmed
This case is unique in that a free fibula flap had never been used to obliterate the frontal
sinus in a
patient with
Freeman - Sheldon syndrome , nor had it been harvested from a limb with a
clubfoot . -
pubmed
This report describes the case of a 32 - year - old
woman who has been experiencing
temporomandibular joint ankylosis for a period of 8 years . -
pubmed
An analysis of treatment of 133
patients with acute
pancreatitis using minimally invasive surgical interventions ( laparoscopic and puncture - draining operations ) has shown that in cases of total
pancreonecrosis these methods were little effective in most cases as a definitive method of surgical treatment and may be considered as the first stage of complex process of treatment . -
pubmed
However , for certain forms of
pancreonecrosis the minimally invasive surgery plays one of the leading roles in the improvement of results of treatment in the general population of
patients with destructive
pancreatitis . -
pubmed
Predictors of surgical outcome in
children with
vesicoureteral reflux associated with
paraureteral diverticula . -
pubmed
METHODS : Records of 51
patients who underwent surgical treatment for
PUD were reviewed . -
pubmed
Morphofunctional changes in the thyroid gland in
animals with the central and peripheral mechanisms of the development and regression of the
nonthyroid disease syndrome were detected . -
pubmed
OBJECTIVE : To compare length of stay , readmissions ,
infections , and mortality in
patients with
end - stage renal disease who have been admitted to receive renal transplant , stratified according to
diabetes status and admission
glucose concentration . -
pubmed
Patients were stratified according to
diabetes status before transplant and
glucose concentration at hospital admission (
hyperglycemic [ & gt ; 180 mg / dL ] or normoglycemic [ & lt;= = 180 mg / dL ] ) . -
pubmed
When stratified according to
glucose concentration at admission ,
patients with
hyperglycemia had a significantly longer length of stay than normoglycemic
patients ( 10 + - 4.3 days vs 7.9 + - 2.9 ; P = .039 ) , even after correcting for
diabetes status . -
pubmed
CONCLUSION :
Hyperglycemia at hospital admission , rather than a known diagnosis of
diabetes , is associated with increased length of stay in
patients admitted for renal transplant . -
pubmed
Human papillomavirus ( HPV ) testing is routinely performed on
oropharyngeal carcinomas . -
pubmed
ISH and AGPCR have comparable performance for the detection of
HPV in oropharyngeal
carcinomas . -
pubmed
PCR is a suitable and economical assay that is comparable to ISH in sensitivity and may provide logistical advantages relative to ISH for assessing
HPV status in
oropharyngeal malignancies . -
pubmed
PATIENTS AND METHODS : Forty
patients with
hip fractures with normal contralateral hips were selected for this study between 2003 and 2007 (
trochanteric fracture , n=18 ;
femoral neck fracture , n=22 ) . -
pubmed
Patients with
trochanteric fractures showed a smaller neck shaft angle and smaller cortical index at the femoral canal isthmus compared with patients with
femoral neck fractures . -
pubmed
CONCLUSIONS : We conclude that severe
osteoporosis with thinner cortical bone of the femoral diaphysis is seen more often in
patients with
trochanteric fracture than in
patients with
femoral neck fracture . -
pubmed
OBJECTIVE : To document the influence of age on step activity patterns in
children with
cerebral palsy (
CP ) and typically developing ( TD )
children . -
pubmed
Seizure and altered mental status in a 12 - year - old child with
Shigella sonnei gastroenteritis . -
pubmed
We report here the first case of
SLE - induced
DAH treated successfully with
rituximab without
cyclophosphamide administration in a
patient intolerant to
cyclophosphamide . -
pubmed
Thus , CMR perfusion stress testing has been deemed appropriate for the evaluation of
chest pain syndromes in
patients with intermediate probability of
coronary artery disease (
CAD ) and for ascertaining the physiologic significance of indeterminate
coronary artery lesions . -
pubmed
Probiotics are able to decrease the permeability of the intestinal wall , and decrease
bacterial translocation and
endotoxemia in animal models as well as in clinical studies , which is extremely important in the prevention of complications of
liver cirrhosis and
infection after liver transplantation . -
pubmed
Peak nasal inspiratory flow ( PNIF ) can help in the assessment of
patients with
allergic rhinitis . -
pubmed
METHODS : : A retrospective analysis of all
patients undergoing repair of
AAA during 2007 . -
pubmed
The endovascular group included three
patients with contained retroperitoneal
rupture , one of whom died secondary to visceral embolization and
thrombosis ( the only mortality ) . -
pubmed
Defects in this response can result in
airway remodeling , such as mucus cell
metaplasia (
MCM ) , commonly seen in
patients with
chronic lung disease . -
pubmed
The effects of Pilates on metabolic control and physical performance in
adolescents with
type 1 diabetes mellitus . -
pubmed
UNLABELLED : Physical activity is a substantial method in the management of
children and
adolescents with
Type 1 diabetes mellitus but it is not considered as a treatment for
diabetes . -
pubmed
The aim of this study was to investigate the effects of Pilates exercises on metabolic control and physical performance in
patients with
type 1 diabetes mellitus . -
pubmed
Thirty one sedentary
patients with
type 1 diabetes mellitus , ranging in age from 12 to 17 ( experimental group , n=17 and control group , n=14 ) were submitted to 12 weeks of Pilates training . -
pubmed
CONCLUSIONS : Physical performance increased via Pilates exercises in the
patients with
type 1 DM . -
pubmed
In the present study , the positive effects of exercise on metabolic control could not be shown in
patients with
Type 1 DM . -
pubmed
Twenty - three heat - sensitive
MS subjects and 19 healthy controls participated . -
pubmed
pneumoniae ,
Neisseria meningitidis type C ( MenC ) , and/or
Haemophilus influenzae type b (
Hib ) . -
pubmed
In the current study we examined the effects of
27 - and 24 - hydroxycholesterol on viability of
human neuroblastoma SH - SY5Y cells treated with
staurosporine , a toxic substance that induces apoptosis . -
pubmed
These genes code for two enzymes involved in
fatty - acid metabolism , and we have demonstrated in
human cells that the
HSP pathophysiology includes alteration of mitochondrial architecture and bioenergetics with increased oxidative stress . -
pubmed
Systemic administration of
human adipose - derived stem cells reverts
nociceptive hypersensitivity in an experimental model of
neuropathy . -
pubmed
We have investigated the effect of hASCs injected in a model of
neuropathic pain [ (
mouse sciatic nerve chronic constriction injury (
CCI ) ] . -
pubmed
No
mouse died , and no macroscopic
toxicity or behavioral changes were observed , confirming the safety of hASCs . -
pubmed
injected into
C57BL / 6 mice when the
neuropathic pain was already established , induced a significant reduction in mechanical
allodynia and a complete reversion of thermal
hyperalgesia in a dose - response fashion , already 1 day after administration . -
pubmed
In some
patients ,
optic neuropathy may improve with intravitreal
steroids or anti - angiogenic agents . -
pubmed
For applications that are geared towards
children , such as retinal birefringence scanning for
strabismus screening purposes , it is important to know the expected range of both corneal retardance and azimuth in pediatric populations . -
pubmed
Breastfed
infants are at especially high risk of
vitamin D deficiency due to poor penetrance of
vitamin D metabolites into milk . -
pubmed
Resolution of
intracardiac and pulmonary thrombi without anticoagulation in a
patient with
Behcet ' s disease : a case report . -
pubmed
We report a
patient who was found to have multiple right
intraventricular and bilateral pulmonary artery thrombi and was clinically diagnosed with
Behcet ' s disease . -
pubmed
We conclude that intracardiac
thrombi in
patients with
Behcet ' s disease may resolve with immunosuppressants without anticoagulation , which is especially important in
patients with contraindication to anticoagulation . -
pubmed
Enrolled
patients were diagnosed with
PTCL , confirmed by a referenced pathologist , treated with the new chemotherapy ACEP X 6 (
Doxorubicine 75 mg / m2 on day 1 +
Cyclophosphamide 1,200 mg / m2 on day 1 +
Etoposide 300 mg / m2 on day 1 and
Prednisolone 60 mg / m2 from day 1 through day 5 ) and
Ifosfamide X 4 (
Ifosfamide 4 grams / m2 on day 1 ) which were given after the completion of the first 6 cycles of ACEP . -
pubmed
However , a larger sample is needed to make it an acceptable new combination chemotherapy for
PTCLs patients . -
pubmed
RESULTS : Eighteen studies with a total of 761
bipolar disorder patients and 919 healthy controls were included . -
pubmed
Studies with immunodeficient
mice showed that the
mouse genetic background does not alter omental milky
spot number and size , nor does it affect
ovarian cancer colonization . -
pubmed
Working memory in
ALS patients : preserved performance but marked changes in underlying neuronal networks . -
pubmed
The smaller CDA in the patients could be attributed to more ipsilateral cortical activity which may indicate that
ALS patients unnecessarily processed the irrelevant stimuli as well . -
pubmed
We report herein two cases of
patients with lesions clinically and microscopically compatible with the diagnosis of circumscribed
palmoplantar hypokeratosis . -
pubmed
OBJECTIVE : To discuss the drug intervention in diversity changes of TCRVbeta gene in
AIDS patients with incomplete immune reconstitution . -
pubmed
METHOD : PBMCs were isolated from 37 cases of
AIDS patients failure to immune reconstitution before and after treatment with immune 2 and 15 cases of
HIV negative healthy donors . -
pubmed
Embryonic exposure to
corticosterone modifies
aggressive behavior through alterations of the hypothalamic pituitary adrenal axis and the serotonergic system in the
chicken . -
pubmed
Female BALB / c
mice were randomly assigned to one of the four groups : the negative control group , the parental
corn group , the GM
corn group and the positive control group with 10
mice per group . -
pubmed
The aim of this study was to determine the anticancer effects of
urushiol in
human gastric
adenocarcinoma cell lines . -
pubmed
RESULTS : The cytotoxic results from
MTT assays indicated that
urushiol inhibited
human gastric cancer cell growth in a dose - dependent manner , with IC50 values of approximately 15 and 20 mug / ml on
MKN-45 and
MKN-28 cells , respectively . -
pubmed
CONCLUSIONS : These data provide evidence that
urushiol has the potential to be used as a chemotherapeutic agent in
human gastric cancer . -
pubmed
Until the late 1980s , physical exercise training was a contraindication in
patients with
heart failure . -
pubmed
Observational data support lower recurrence rates and improved survival after
radioiodine ablation in
patients with high - risk
cancers ; however , a similar benefit has not been established for all
patients with
thyroid cancer . -
pubmed
METHODS : Peripheral venous blood was sampled from 75 septic
patients ( 39
patients with
sepsis , 25 with severe
sepsis and 11 with
septic shock ) on
sepsis days 1 , 3 and 7 . -
pubmed
MATERIAL AND METHODS : Authors studied 40
patients ( 23
men and 17
women , mean age 31.8 years ) with mild and moderate
depression comorbid with symptoms of
panic disorders . -
pubmed
Magnetic resonance imaging findings in
patients presenting with ( sub)acute
cerebellar ataxia . -
pubmed
Previous magnetic resonance ( MR ) studies in single
patients who developed acute or subacute
ataxia showed varying imaging features . -
pubmed
METHODS : Eighteen
patients presenting with acute and subacute onset of
ataxia were included in this study . -
pubmed
RESULTS : An underlying etiology for
ataxic symptoms were found in 14/18
patients ( postinfectious / infectious , paraneoplastic , autoimmune , drug - induced ) . -
pubmed
In two of five
patients without MR imaging findings and three of eight
patients with minimal imaging features (
cerebellar atrophy , slight signal alterations , and small areas of restricted diffusion ) , adverse clinical outcomes were documented . -
pubmed
Of the five
patients with prominent MR findings (
cerebellar swelling , contrast enhancement , or broad signal abnormalities ) , two were lost to follow - up and two showed long - term sequelae . -
pubmed
CONCLUSION : No correlation was found between the presence of initial MRI findings in subacute or acute
ataxia patients and their long - term clinical outcome . -
pubmed
PATIENTS AND METHODS : 120
patients with ultra - early
basal ganglia intracerebral hemorrhage were randomly divided into experimental group ( strengthened antihypertensive ) and control ( normal antihypertensive ) . -
pubmed
METHODS AND MATERIALS : From 2005 to 2012 , 18
patients with biopsy proven locally recurrent
prostate cancer and negative staging received low - dose - rate BT with a prescribed dose of 130 - 144 Gy . -
pubmed
Late Grade 3/4
genitourinary toxicity occurred in 1
patient each , one of whom also had Grade 3 late
gastrointestinal toxicity ;
urethral strictures developed in three others . -
pubmed
These 5
patients with late
toxicity had higher dose to the prostate ( isodose enclosing 90 % [ D90 ] median , 151 Gy ; range , 135 - 185 Gy ) compared with those without late complications ( median , 134 Gy ; range , 105 - 165 ; p & lt ; 0.04 ) . -
pubmed
Considering drug metabolism and pharmacokinetics , we have established nonclinical
animal models of
DILI for 10 types of clinical drug known to cause idiosyncratic
DILI in
humans . -
pubmed
Using
animal models , it has been shown that the formation of reactive metabolites and both innate and adaptive immunity are involved in the pathogenesis of
drug hepatotoxicity . -
pubmed
Based on information on biomarkers obtained from
animal models , we developed a cell - based system that predicts the potential
DILI risks of drugs . -
pubmed
A study of cognitive functions in female elderly
patients with
osteoporosis : a multi - center cross - sectional study . -
pubmed
METHODS : This cross - sectional study included 277 postmenopausal
women , who were divided into an
osteoporosis patients group ( n = 170 ) and an age , gender and educational history matching control group ( n = 107 ) . -
pubmed
RESULTS :
Individuals with
osteoporosis had poorer cognitive scores ( P & lt ; 0.001 ) . -
pubmed
CONCLUSIONS :
Patients with
osteoporosis are prone to
cognitive impairments especially declarative
memory deficits . -
pubmed
Experiments were conducted with four neutrophilic bacterial
strains , including the Gram - negative
Escherichia coli and
Pseudomonas putida and the Gram - positive
Bacillus subtilis and
Staphylococcus epidermidis . -
pubmed
Evaluating
Human T - Cell Therapy of
Cytomegalovirus Organ Disease in HLA - Transgenic
Mice . -
pubmed
The model has thus proven its potential for a preclinical testing of the protective antiviral efficacy of
HCMV epitope - specific
human T cells in the evaluation of new approaches to an immunotherapy of
CMV disease . -
pubmed
Sleep - associated aspects of
myofascial pain in the orofacial area among
Temporomandibular Disorder patients and controls . -
pubmed
STUDY OBJECTIVES : To assess sleep - associated aspects of
temporomandibular disorder (
TMD ) with
myofascial pain (
MP ) in the orofacial area of
patients and controls . -
pubmed
MEASUREMENTS : Three hundred five female
patients were screened to find 44 participants fulfilling the inclusion criteria , 22 suffering from
MP and 22 in a control group . -
pubmed
Selenoprotein T Deficiency Leads to
Neurodevelopmental Abnormalities and
Hyperactive Behavior in
Mice . -
pubmed
Introducing germplasm from exotic sources especially from another cultivated
tetraploid G. - pubmed
Chronic
West Nile virus infection in kea (
Nestor notabilis ) . -
pubmed
OBJECTIVE : To compare secondary conditions in
people with
traumatic spinal cord injury (
SCI ) and
non - traumatic spinal cord dysfunction (
SCDys ) . -
pubmed
PARTICIPANTS :
Adults with
spinal cord damage from any cause . -
pubmed
A genome - wide expression profile analysis reveals active genes and pathways coping with
phosphate starvation in
soybean . -
pubmed
The Effect of Radiotherapy on Ultrasound - Guided Fine Needle Aspiration Biopsy and the Ultrasound Characteristics of Neck Lymph Nodes in
Oral Cancer Patients after Primary Treatment . -
pubmed
OBJECTIVES : To investigate the effect of radiotherapy ( RT ) on ultrasound - guided fine needle aspiration ( USgFNA ) and sonographic characteristics in the assessment of cervical lymph nodes ( LNs ) in
oral squamous cell carcinoma (
OSCC )
patients after primary treatment . -
pubmed
MATERIALS AND METHODS : 88 treated
OSCC patients underwent 111 USgFNAs of the neck LNs after US evaluation . -
pubmed
CONCLUSIONS : RT had influence on sonographic characteristics but no influence on USgFNA in diagnosing recurrent LNs in treated
OSCC patients . -
pubmed
Therefore , changes in commensal microbiota associated with
CRS may alter the normal microbe host dialogue in
humans and be implicated in the pathogenesis of
CRS . -
pubmed
BACKGROUND : The Modification of Diet in
Renal Disease ( MDRD ) equation is widely used to estimate
glomerular filtration rate ( eGFR ) in kidney transplant ( KT )
patients . -
pubmed
Our aim was to compare both equations for staging of
CKD in KT
patients . -
pubmed
METHODS : In a cohort of KT
patients , correlation of eGFR according to MDRD and
CKD - EPI with 24 - hour
creatinine clearance ( 24h - CrCl ) was evaluated . -
pubmed
CONCLUSIONS : The novel CKD - EPI reduces the number of
patients with eGFR & lt;60 mL / min/1.73 m(2 ) and consequently assigns lower
CKD stages to our KT population . -
pubmed
Pathogenic and
viral infections such as Enterotoxigenic
E. - pubmed
coli (
ETEC ) and
porcine epidemic diarrhea virus can lead to loosening the intestinal epithelial barrier . -
pubmed
We report a 70 - year - old
man with
prostate cancer and multiple abdominal , pelvic , and inguinal node
metastases . -
pubmed
Assessment of atrial conduction times in prediabetic
patients with
coronary artery disease . -
pubmed
We evaluated atrial conduction times ( ACTs ) and atrial electromechanical delays ( EMDs ) in prediabetic
patients with
coronary artery disease (
CAD ) . -
pubmed
METHODS : In the present study , we recruited 128 consecutive
patient candidates ( 40 euglycemic , 48
prediabetic , and 40
diabetic patients ) for coronary artery bypass grafting . -
pubmed
CONCLUSION : There were no significant differences between the euglycemic , prediabetic , and
diabetic patients with
CAD regarding ACTs and atrial EMDs . -
pubmed
Evaluation of adaptive treatment planning for
patients with
non - small cell lung cancer . -
pubmed
The purpose of this study was to develop metrics to evaluate uncertainties in deformable dose accumulation for
patients with
non - small cell lung cancer (
NSCLC ) . -
pubmed
Adaptive planning helps escalate target dose and spare
normal tissue for
patients with
NSCLC , but deformable dose accumulation may have a significant loss of energy in regressed
tumor volumes when using image intensity - based DIR algorithms . -
pubmed
The metric of energy defect is a useful tool for evaluation of adaptive planning accuracy for
lung cancer patients . -
pubmed
Here , we challenge the existence of the idea of
noninfectious sepsis given that
critically ill humans never exist in a germ - free state . -
pubmed
BACKGROUND / AIMS : The
thaliana phytoalexin Camalexin has been proposed for the treatment of
malignancy . -
pubmed
A review of the efficacy of
atomoxetine in the treatment of
attention - deficit hyperactivity disorder in
children and adult patients with common comorbidities . -
pubmed
Importantly , up to 52 % of
children ( including
adolescents ) and 87 % of
adults with
ADHD also have a comorbid
psychiatric disorder . -
pubmed
Despite numerous published studies regarding efficacy of
atomoxetine in the treatment of
ADHD in
patients with comorbid disorders , there is limited information about the impact of individual common comorbid disorders on the efficacy of
atomoxetine for
ADHD , especially with regard to
adults . -
pubmed
For this reason , we performed a literature review to find , identify , and cumulatively review clinical studies that examined the efficacy of
atomoxetine in the treatment of
patients with
ADHD and comorbid
psychiatric disorders . -
pubmed
We found a total of 50 clinical studies ( 37 in
children ; 13 in
adults ) that examined the efficacy of
atomoxetine in
patients with
ADHD and a comorbid disorder . -
pubmed
The comorbidities that were studied in
children or in
adults included
anxiety ,
depression , and
substance use disorder . -
pubmed
Overall , the presence of comorbidity did not adversely impact the efficacy of
atomoxetine in treatment of
ADHD symptoms in both
patient populations . -
pubmed
Human herpesvirus-8 and human
cytomegalovirus infections in
Bowen ' s disease : Is there any association ? -
pubmed
RESULTS : The
patient was admitted at the age of 5 months due to severe
epilepsy and marked delayed psychomotor development . -
pubmed
In present review , an attempt has been made to generate awareness among the readers about various sources of occurrence of
arsenic , its geochemistry and speciation , mobilization , metabolism ,
genotoxicity , and toxicological exposure on
humans . -
pubmed
SSMT is otherwise uncommon with an incidence of up to 7 % in asymptomatic
individuals . -
pubmed
The aim of this study was to evaluate the incidence and clinical significance of SSMT in
patients with
PA and a control group of surgically treated non - functioning
pituitary adenomas (
NFPAs ) . -
pubmed
METHODS : Retrospective review of clinical and imaging variables in PA and
NFPA patients . -
pubmed
PA patients were managed conservatively ( N = 11 ) or surgically ( N = 36 ) . -
pubmed
Physiological factors such as liver fluke (
Fasciola hepatica ) infection , breeding status , and in - tissue element interactions may also affect tissue concentrations , though their effects in
red deer are not well understood . -
pubmed
These
tumors can be found in all age groups , but are more common in older
patients ; with the cutaneous form most common in older white
men . -
pubmed
CASE PRESENTATION : Here we describe the case of a 63 - year - old
man who presented initially with
angiosarcoma of the nose and received surgery for the primary . -
pubmed
The most active hydrolysate was then tested for blood pressure - lowering ability in spontaneously
hypertensive rats ( SHRs ) . -
pubmed
METHODOLOGY AND PRINCIPAL FINDINGS : Ninety - three unrelated
individuals with molecularly unassigned
spinocerebellar ataxia selected from 585 pedigrees with
autosomal dominant cerebellar ataxias , were recruited into the study with elaborate clinical evaluations . -
pubmed
The treatment of
patients with
TNBC remains a great clinical challenge . -
pubmed
We present the case of a female 34 - year - old
patient with
acute kidney injury symptoms with indication for renal replacement therapy in the context of clinical
SLE diagnosis . -
pubmed
We isolated 75 Cercomonadida
strains from the phyllosphere and rhizosphere of plants from three functional groups : grasses (
Poa sp . ) , legumes (
Trifolium sp . ) and forbs ( Plantago sp . ) -
pubmed
A systematic review of literature from 2011 to 2016 was performed , in order to evaluate the diagnostic performance of inflammatory biomarkers in
children with
fever without apparent source and their usefulness in clinical decision - making . -
pubmed
Recently , microRNA-372 ( miR372 ) has been proven to play a substantial role in several
human cancers , but its functions in
liver cancer remain unclear . -
pubmed
We report a 44 - year - old
woman with
anemia and
uterine IMT . -
pubmed
Our aim was to investigate the effects of a MAP - guided management in a
bleeding - resuscitation
animal experiment . -
pubmed
First Pediatric Case of
Infective Endocarditis Caused by
Serratia Liquefaciens . -
pubmed
Infective endocarditis (
IE ) caused by
Serratia liquefaciens has been reported in only 2 adults . -
pubmed
We experienced the first pediatric ( neonatal ) case of
IE caused by
S. - pubmed
OBJECTIVE : Home nebulizers are routinely used in the treatment of
patients with
cystic fibrosis (
CF ) . -
pubmed
This study aims to evaluate the contamination of nebulizers used for
CF patients , that are chronically colonized by
Pseudomonas aeruginosa , and the association of nebulizer contamination with cleaning , decontamination and drying practices . -
pubmed
Genetic Profiling of
Aggregatibacter actinomycetemcomitans Serotype B Isolated from
Periodontitis Patients Living in Sweden . -
pubmed
The bacterium
Aggregatibacter actinomycetemcomitans is associated with aggressive forms of
periodontitis and with
systemic diseases , such as
endocarditis . -
pubmed
We describe frequent T - cell - based immune responses against this epitope in
patients with
cancer , as well as in healthy donors . -
pubmed
We here report the results of an uncontrolled case series of
patients with refractory
tremor who underwent deep brain stimulation under tractographic assistance . -
pubmed
In this study , we attempt to explore the prognostic significance of the AAPR in
stage IB - IIA cervical cancer patients who underwent a radical hysterectomy . -
pubmed
Patients and methods : A total of 230
cervical cancer patients were enrolled in this retrospective study . -
pubmed
Conclusion : Preoperative AAPR was a potentially valuable prognostic index in
stage IB - IIA cervical cancer patients . -
pubmed
We present 3
patients successfully treated for their
septal perforation and septal deviation concurrently with this technique . -
pubmed
In the 47
patients who survived for longer than 9 months and were evaluated for
BOS after the transplant , BOS was not related to DSA or PRA levels . -
pubmed
Zanubrutinib for the treatment of
patients with
Waldenstrom macroglobulinemia : three years of follow - up . -
pubmed
Patients had disease requiring treatment per International Workshop on
Waldenstrom Macroglobulinemia ( IWWM ) criteria . -
pubmed
At a median follow - up of 36.0 months for
patients with R / R disease and 23.5 months for
TN , 72.7 % remained on treatment . -
pubmed
Reasons for treatment discontinuation included any adverse events in 13.0 % of
patients ( 1 treatment related ) ,
disease progression ( 10.4 % ) , and other ( 3.9 % ) . -
pubmed
Long - term treatment with single - agent
zanubrutinib resulted in deep and durable responses in some
patients with
WM . -
pubmed
Marker chromosome is a strong poor prognosis factor after allogeneic HSCT for adverse - risk
AML patients . -
pubmed
OBJECTIVE AND METHODS : We retrospectively analyzed 162
AML patients after allo - HSCT . -
pubmed
RESULT :
MC was detected in 14 ( 8.6 % , MC+ )
patients ( vs. MC- , n=158 ) . -
pubmed
Desmopressin acetate decreases
blood loss in
patients with massive
hemorrhage undergoing gastrointestinal surgery . -
pubmed
This study was to investigate whether
DDAVP can decrease
blood loss in
patients with massive
hemorrhage undergoing gastrointestinal surgery . -
pubmed
88
patients were divided into moderate ( 47 [ 53.41 % ] ) , severe ( 32 [ 36.36 % ] ) and
critically ill ( 9 [ 10.23 % ] ) groups . -
pubmed
Newly synthesized derivatives were evaluated for their anticancer potential against
human malignant glioma U87 (
MG - U87 ) cell lines at different concentrations of 200 muM , 100 muM , 50 muM , 25 muM , 12.5 mum , 6.25 mum and 0 muM. -
pubmed
They are especially indicated for
patients who have conditions producing
pain of short duration or for terminal
patients . -
pubmed
Radiotherapy may temporarily help most
patients with intractable
pain . -
pubmed
Open or stereotactic surgical intervention and especially interruption of the ascending
pain fibers within the spinal cord may give permanent relief to
patients who have increasingly severe
pain . -
pubmed
Partial characterization of a fetal lung antigen associated with
human bronchogenic carcinoma . -
pubmed
Twelve arches in eight
patients with moderate to severe
bone loss were selected for this investigation . -
pubmed
Fasting & amp ; postprandial blood
sugar studies in treated & amp ; untreated
diabetic patients . -
pubmed
Relationship of the constituents of bile to
biliary peritonitis in the
rat . -
pubmed
This paper describes an
animal model to determine which of the major solid components of bile are responsible for peritoneal destruction in
biliary peritonitis . -
pubmed
In the
rat ,
bile salts within the peritoneal cavity cause
peritonitis but
cholesterol and
lecithin are without deleterious effect . -
pubmed
Renal tissue from 6
patients with
glomerulonephritis associated with
cryoglobulinemia was studied by light microscopy , immunofluorescence microscopy , and electron microscopy . -
pubmed
Proceedings : An improved technique for producing hemorrhageous
erosions in the female
rat : its application in studies on the role of
histamine in
stress ulcer pathogenesis . -
pubmed
Hepatic
cholesterol metabolism in
patients with
gallstones . -
pubmed
Obstructive hydrocephalus was induced in 12 - day - old
rats by the infusion of kaolin into the cisterna magna . -
pubmed
Loss of righting reflex (
precoma stage of PSE ) was accompanied by 2 - 3 fold increased CSF
lactate and onset of
coma by 4 - fold increases of
lactate ( p less than 0.001 compared to either
sodium acetate treated portacaval shunted
rats or sham - operated controls administered
ammonium acetate ) . -
pubmed
Similar mechanisms could be involved in the pathogenesis of PSE in
patients with
chronic liver disease . -
pubmed
The biodistribution in
mice bearing
melanoma either
human or animal from 4 to 24 hrs . -
pubmed
Nevertheless , the combination of surgery and postoperative chemotherapy helped to prolong the life of
patients with
Wilms ' tumors . -
pubmed
B19 parvovirus infection is a principal cause of transient
bone marrow suppression in
patients with
chronic haemolytic anaemias . -
pubmed
BACKGROUND : Clinical
vitamin A deficiency affects millions of
children worldwide , and
subclinical deficiency is even more common . -
pubmed
The base - line characteristics of the
children were similar and documented a high prevalence of
vitamin A deficiency and
undernutrition . -
pubmed
The risk was most reduced among
children under 3 years of age ( 6 to 11 months -- relative risk , 0.28 ; 95 percent confidence interval , 0.09 to 0.85 ; 12 to 35 months -- relative risk , 0.46 ; 95 percent confidence interval , 0.26 to 0.81 ) and among those who were chronically undernourished , as manifested by
stunting ( relative risk , 0.11 ; 95 percent confidence interval , 0.03 to 0.36 ) . -
pubmed
Unilateral
degeneration of retina and optic nerve in
Fischer-344 rats . -
pubmed
Unilateral
degeneration of the retina and optic nerve was observed among Fischer-344 ( F-344 )
rats fed a semi - purified synthetic feed . -
pubmed
No
ocular lesions were observed in any F-344
rats prior to 21 weeks of age , whether fed a synthetic diet or a standard diet ; however , approximately 16 % ( 13/86 ) of the F-344
rats examined between 57 and 64 weeks of age developed unilateral
degeneration of the retina and optic nerve . -
pubmed
On the other hand , the F-344
rats fed the synthetic diet developed the
degenerative lesions by 30 weeks of age , while the F-344
rats fed the standard diet did not develop lesions over this shorter time period . -
pubmed
In contrast with the F-344
rats , Long - Evans
rats that were fed either the synthetic or standard diet up to the age of 68 weeks ( 77
rats ) did not develop the
ocular lesions . -
pubmed
There was no apparent relationship of the development of the lesions with dietary modification ,
toxicity or
trauma ; thus , these observations appear to indicate that spontaneous unilateral
degeneration of the retina and optic nerve occurs in F-344
rats and that these
ocular lesions may be accelerated by the feeding of certain semi - purified synthetic diets . -
pubmed
Food intake per 100 g
body weight was significantly increased between postoperative days 14 and 35 in the jejunoileal bypass
rats . -
pubmed
Bacterial
tracheitis caused by
Branhamella catarrhalis . -
pubmed
Although the cause of
death was cardiac related in 50 % of the
patients who died , survival was comparable with that of an age - matched and sex - matched general population . -
pubmed
Acute event - free status ( freedom from
acute myocardial infarction , repeat coronary artery bypass grafting , percutaneous transluminal coronary angioplasty , or
death ) persisted at 15 years in 43.2 % of
patients . -
pubmed
Prevention of
DOCA - induced
hypertension in
rats by chronic treatment with
tryptophan . -
pubmed
Hypertension developed within 5 weeks in uninephrectomized
rats administered
deoxycorticosterone acetate (
DOCA , 30 mg / kg , s.c . -
pubmed
Treatment with
tryptophan also protected against the reduction in urinary concentrating ability during a 24 h
dehydration that is characteristic of
DOCA - treated
rats . -
pubmed
These results suggest that
tryptophan provides significant protection against the development of
DOCA - induced
hypertension ,
polydipsia , and
cardiac hypertrophy in
rats . -
pubmed
Two
patients with
small cell carcinoma of the lung who presented with
lactic acidosis are described . -
pubmed
In 62 untreated
patients with essential
hypertension , arterial baroreflex sensitivity ( BRS ) for heart rate , i.e. -
pubmed
A series of earlier studies showed that inhalation exposures of
rats to three water - reactive electrophilic compounds produced brisk yields of
nasal cancer even when the
animals were exposed for only 30 days ( 6 hr / day X 5 day / wk ) . -
pubmed
With this protocol , all compounds except PO ( the slowest reacting compound ) produced
nasal cancer in
rats . -
pubmed
The concentrations of
MMS and
BPL employed in the studies produced similar
nasal cancer yields , indicating that the carcinogenic potencies of these compounds in
rat nasal mucosa were proportional to their hydrolysis rates . -
pubmed
The single breath diffusing capacity of the lung for
carbon monoxide ( Dsb ) was measured using three equations to describe
CO uptake separately during inhalation , breath holding , and exhalation in 24
patients with
cystic fibrosis and 30 control subjects with similar age and height distributions . -
pubmed
In a multicenter study 153 in- and
outpatients suffering from severe
pain were treated for three weeks with capsules containing 50 mg
1 -( m - methoxyphenyl )- 2 -( dimethylaminomethyl )- cyclohexan-1 - ol (
tramadol ,
Tramal ) . -
pubmed
Protective effect of
polyphloretin phosphate in
anaphylaxis in the
guinea pig . -
pubmed
[ Reticuloendothelial blockers -- effects of carrageenan and dextran sulfate on the function of the
mouse mesangium in processing
foreign bodies ] . -
pubmed
Two - stage
carcinogenesis studies with asbestos in
Fischer 344 rats . -
pubmed
The systemic absorption of
amphotericin B , administered as a 10 mg lozenge , was investigated in 14
patients with
malignancies , who received three or four doses daily during chronic administration . -
pubmed
[ Pathologic correlation between
periodontal disease and
diabetes mellitus in a
patient with metabolism disorders ] . -
pubmed
The minimum inhibitory concentrations of 45 antimicrobial agents were established by the agar dilution method for 37
strains of Bacteroidaceae :
Bacteroides fragilis ( 18
strains ) ,
B. - pubmed
thetaiotaomicron ( 8
strains ) ,
Fusobacterium nucleatum ( 6
strains ) , and Fusobacterium spp . -
pubmed
Three quaternized compounds elicit a significative but low antileukemic activity on
L1210 mice leukemia . -
pubmed
A two - phase liquid - culture system was used to substantially amplify and differentiate erythroblasts , starting with mononuclear cells from the blood of normal
adults , newborn infants , and
patients with
sickle cell anemia . -
pubmed
A
patient was diagnosed with
Cushing ' s syndrome during her first pregnancy . -
pubmed
The retinal electrophysiology is reported in four
patients with
type II mesangiocapillary glomerulonephritis and partial
lipodystrophy with associated
fundus abnormalities and no
visual symptoms . -
pubmed
The appearance of a second
neoplasm in these
patients represents an important decrease in survival . -
pubmed
RESULTS : Ten of the 78
patients studied ( 13 % ) developed a second
neoplasm . -
pubmed
In 9 of the 10
patients the appearance of the second
neoplasm was considered metachronic with 60 % being detected within the first 24 months after the diagnosis of the
laryngeal neoplasm . -
pubmed
Survival of the
patients with the second
neoplasm was lower : 71 % at 2 years and 5 % at 5 years ( p & lt ; 0.0001 ) . -
pubmed
CONCLUSIONS : The presence of a second
neoplasm in
patients with
laryngeal cancer is high . -
pubmed
The survival of
patients with advanced
laryngeal cancer who develop a second
neoplasm is significantly lower than that of other
patients with this
neoplasm . -
pubmed
We report the case of a 40 year old
woman , presenting with progressive
respiratory failure and bilateral pulmonary infiltrates . -
pubmed
A case of unilateral vitreous
relapse in a
patient with
primary central nervous system lymphoma (
PCNSL ) following sequential systemic chemotherapy and radiotherapy is reported . -
pubmed
Kidney biopsies were performed in 7
patients : 4
HIV - associated
nephropathies (
HIV AN ) with segmental and focal hyalinizations , 1
thrombotic angiopathy , and 2
interstitial nephropathies , 1 with
proliferative glomerulonephritis . -
pubmed
The clinical , biological and radiographic patterns of 2 of the remaining 3
patients were suggestive of
HIV AN . -
pubmed
Four of the 6
patients with
HIV AN developed
end - stage renal disease within 5 + /- 2.5 months ; renal function in the other 2 remained stable for 25 and 41 months , respectively , while they were receiving
zidovudine , but deteriorated rapidly within weeks of withdrawing this drug . -
pubmed
Zidovudine may have delayed the evolution of the
nephropathies in these
patients . -
pubmed
OBJECTIVE : The authors determined which combination of computed tomography scans is most helpful for preoperative assessment of
patients with
liver tumors . -
pubmed
SUMMARY BACKGROUND DATA : Multi - institutional studies have shown that the most important prognostic factors for selection of
patients with metastatic
colorectal cancer considered for liver resection are : Dukes ' stage of primary
tumor , the number of hepatic
metastases if greater than 3 , the presence of
extrahepatic cancer , and the ability to resect
tumors with an adequate margin ( & gt ; 1 cm . ) -
pubmed
Therefore the ability to predict the presence of
extrahepatic disease and the number and location of
hepatic tumors are important in these
patients . -
pubmed
METHODS : One hundred and nine consecutive
patients with evidence of
hepatic tumors were evaluated by computed tomography with arterial portography ( CTAP ) and abdominal computed tomography after a 4 - hour delay ( CT - D ) . -
pubmed
METHODS : Thirty two biopsy specimens of
Kaposi sarcoma ( 29
patients ) were studied . -
pubmed
Effect of thyroid substitution on
hypercholesterolaemia in
patients with
subclinical hypothyroidism : a reanalysis of intervention studies . -
pubmed
( 2 ) Precision weighted pooled estimates of the effect of thyroid substitution therapy on the plasma levels of total
cholesterol , in
patients with subclinical and overt
hypothyroidism . -
pubmed
RESULTS : Subclinical
hypothyroidism was two to three times more frequent in
people with an elevated total plasma
cholesterol . -
pubmed
In addition , the total plasma
cholesterol levels were slightly elevated in
patients with
subclinical dysfunction of the thyroid . -
pubmed
The effect of thyroid substitution in
patients with overt
hypothyroidism was highly dependent on the pretreatment levels of total
cholesterol . -
pubmed
CONCLUSIONS : Thyroid substitution treatment in
patients with
hypercholesterolaemia and
subclinical hypothyroidism decreases total plasma
cholesterol by 0.4 mmol / l , but plasma levels remain elevated in most
patients . -
pubmed
Mutations in the long control region of
human papillomavirus DNA in
oral cancer cells , and their functional consequences . -
pubmed
Oral cancers frequently contain DNA of
human papillomavirus ( HPV ) type 16 or 18 , but the functional significance of this is unclear . -
pubmed
A role for
HPV in the progression of
oral cancer would be more plausible if the viral transforming genes were likely to be overexpressed in
oral cancer cells . -
pubmed
We therefore isolated and sequenced the long control region ( LCR ) of
HPV-16 or
HPV-18 from three
oral cancer cell lines and two lines of
HPV-16 - immortalized oral keratinocytes , using PCR . -
pubmed
These results imply that mutations in the LCR of
HPVs in
oral cancer could lead to increased expression of
HPV - transforming proteins , which might contribute to the carcinogenic process . -
pubmed
While
strain M3GY could grow on
DPE , cells grown on
DPE as a sole
carbon source could not degrade
DDE . -
pubmed
We have tested how the plasma of
patients with
acute myocardial infarction affects this process . -
pubmed
METHODS AND RESULTS : Citrated plasma was obtained from 18
patients with
acute myocardial infarction within 6 hours from the onset of symptoms and from 26 control
subjects with
chest pain syndrome without evidence of
ischemia . -
pubmed
those
patients with genetic or acquired
lymphopenia . -
pubmed
Matching donors and recipients for
HCV genotype may minimize the risk of
superinfection when using kidneys from
HCV - positive donors ( RR 1.4 , p = 0.02 for the D+/R- mismatch ) . -
pubmed
To study sensitivity and
poliovirus serotype - specificity , 129 sera and 115 CSF specimens from
children with
acute poliomyelitis were used in comparative tests with the in - house RIA . -
pubmed
SUBJECTS : 129
obese children ( 67
girls and 62
boys ) , 142 normal - weight controls ( 81
boys and 61 girls ) , and mothers ( n = 245 ) and fathers ( n = 222 ) of the children . -
pubmed
AIMS : To investigate the effect of
alosetron on whole gut , small bowel and colonic transit in
patients with
irritable bowel syndrome ( Study 1 ) and healthy
volunteers ( Study 2 ) . -
pubmed
SUBJECTS : Thirteen
patients with
irritable bowel syndrome and 12 healthy
volunteers . -
pubmed
RESULTS :
Alosetron increased colonic transit time by prolonging left colonic transit in both
patients with
irritable bowel syndrome and controls . -
pubmed
This resulted in a tendency for the whole gut transit to be delayed in
irritable bowel syndrome patients ( P=0.128 ) , which was confirmed in controls ( P=0.047 ) . -
pubmed
These results add to the body of evidence suggesting that
alosetron should have a therapeutic role in
patients with
non - constipated irritable bowel syndrome . -
pubmed
These regions may also overlap with the syntenic region of the
glomerulosclerosis susceptibility locus in the BUF / Mna
rat . -
pubmed
Biodistribution of
paclitaxel and
poly ( L - glutamic acid )- paclitaxel conjugate in
mice with
ovarian OCa-1 tumor . -
pubmed
METHODS : Female
C3Hf / Kam mice bearing syngeneic ovarian
OCa-1 tumors were injected with either
[ 3H ] TXL or
PG -[ 3H ] TXL at an equivalent
TXL dose of 20 mg / kg . -
pubmed
Mice were killed at various times after drug injection , and samples of blood , spleen , liver , kidney , lung , heart , muscle , brain , fat , and
tumor were removed and the radioactivity counted . -
pubmed
Autoradiographic images of
mice injected with
PG -[ 3H ] TXL revealed that radioactivity was primarily located in the periphery of the
tumor on day 1 after drug administration and was homogeneously diffused into the center of the
tumor by day 6 . -
pubmed
Patients received an intravenous infusion
MDXH210 during a period of 2 h three times per week for 2 weeks and were monitored for
toxicity . -
pubmed
Based on this fact , thrombolysis may represent a new and effective causal therapeutic strategy in
patients suffering from
cardiac arrest due to
acute myocardial infarction or
fulminant pulmonary embolism . -
pubmed
This effect might be responsible for the exceptionally good neurological outcome observed in
patients treated with thrombolytic agents during cardiopulmonary resuscitation and might be a result of the proven imbalance of the endogenous coagulation system in
patients suffering from
cardiac arrest . -
pubmed
This coagulation imbalance is thought to be responsible for postresuscitation
cerebral microcirculatory reperfusion disorders in
patients after
cardiac arrest and cardiopulmonary resuscitation . -
pubmed
and
Salmonella enterica is a significant source of
human diarrheal disease . -
pubmed
DESIGN : Telephone questionnaire of 50
patients who attended A & amp ; E in 1998 with diagnosis of
Colles fracture SETTING : Glasgow Royal Infirmary within North Glasgow catchment area . -
pubmed
The enigma of occult
mitral regurgitation in a
patient with
cardiogenic shock . -
pubmed
In
patients with
mitral regurgitation (
MR ) , there is a high pressure gradient between the left ventricle ( LV ) and left atrium that Doppler echocardiography can easily detect . -
pubmed
We present a case where transthoracic echocardiography ( TTE ) failed to provide an accurate evaluation of a
patient who presented in
cardiogenic shock . -
pubmed
In addition ,
ADM plasma concentrations in
breast cancer patients and healthy controls were determined by radioimmunoassay . -
pubmed
Investigations into an outbreak of
tuberculosis in a flock of
sheep in contact with tuberculous
cattle . -
pubmed
Tuberculosis , associated with
Mycobacterium bovis infection , occurs infrequently in
sheep . -
pubmed
A
sheep flock , which was potentially exposed to a high level of
infection from in - contact tuberculous
cattle , was examined for evidence of
infection . -
pubmed
Tuberculous lesions were present in four of these
sheep . -
pubmed
This paper describes the first report of an outbreak of
tuberculosis in
sheep in either Britain or Ireland . -
pubmed
Estimates of test characteristics were obtained for 60 consecutive
patients with an
anterior ankle impingement syndrome . -
pubmed
These results suggest the possibility that treatment with
estradiol under low -
calcium conditions can not improve
impaired learning and memory when
progesterone is applied simultaneously , and that the intake of adequate
calcium may be necessary and effective for
patients with
learning and memory hypofunction receiving hormone replacement therapy . -
pubmed
Excessive
daytime somnolence in Japanese
patients with
Parkinson ' s disease . -
pubmed
To investigate the prevalence and severity of
excessive daytime somnolence (
EDS ) in Japanese
patients with
Parkinson ' s disease (
PD ) and to examine the main cause of
EDS . -
pubmed
Fifty - three Japanese
patients with
PD (
PDs : 32 females and 21 males ) and 17 controls ( 10 females and seven males ) were evaluated using the Epworth Sleepiness Scale ( ESS ) . -
pubmed
Metastatic spine tumors affect a large number of
patients each year , resulting in significant
pain , destruction of the spinal column causing mechanical instability , and
neurologic deficits . -
pubmed
In addition ,
cancer patients may have difficulty with access to a radiation treatment facility for prolonged daily fractionated therapy . -
pubmed
CyberKnife spinal radiosurgery offers a new and important alternative therapeutic modality for the treatment of
spinal metastases in medically inoperable
patients , previously irradiated sites , and for lesions not amenable to open surgical techniques or as an adjunct to surgery . -
pubmed
Spinal radiosurgery is likely to become an essential part of any neurosurgical spine center that treats a large number of
patients with
spinal metastases . -
pubmed
The analysis of gray matter structure and connecting white matter paths combined with the ability to bring all information into a common space via intersubject registration should provide us with a rich set of data to investigate structure and variation in the
human brain in
neuropsychiatric disorders , as well as provide a basis for current work in the development of integrated brain function - structure analysis . -
pubmed
Historically , the medical profession has been successful in treating most
bacterial infections in
humans with synthetic second- and third - generation antibiotics . -
pubmed
Infections caused by the Gram - negative bacteria
Pseudomonas aeruginosa and Acinetobacter spp . -
pubmed
OBJECTIVE : To evaluate whether inpatient services within an academic setting were achieving / addressing primary and secondary lipid goals in
patients with established
CAD or
CVD . -
pubmed
The proteomic approach presented here may have broad applications for rapid proteomic analyses of various
mouse models of
human brain diseases . -
pubmed
glycolicum ( 30.6 % similarity between the proposed type
strain of the novel species ,
WAL 16138 , and
C. - pubmed
The type
strain of
C. - pubmed
Human
Trypanosoma cruzi infection and seropositivity in
dogs , Mexico . -
pubmed
A direct correlation ( r2 = 0.955 ) of seropositivity between
humans and dogs suggests that seroanalysis in
dogs may help identify the
human prevalence of
T. - pubmed
BACKGROUND : Currently , no specific immunohistochemical markers are available to differentiate primary
mucinous epithelial ovarian cancer (
MOC ) from
adenocarcinomas originating at other sites that have metastasised to the ovary , which may have an impact on
patient management and prognosis . -
pubmed
The efficiency of screening could be improved by limiting screening to
diabetic patients not receiving
ACE inhibitor / ARB therapy and without known
DKD . -
pubmed
Seventy individual lumbar sympathetic blocks were performed in 13
patients ( six
female , seven
male ; mean age , 45 years ) with
reflex sympathetic dystrophy of the foot . -
pubmed
The question of continuous versus intermittent chemotherapy for
patients with metastatic
colorectal cancer has been an ongoing issue of debate for determining the optimum duration of treatment . -
pubmed
We describe a case of a
patient with
type 2 diabetic end - stage renal disease (
ESRD ) treated by PD who had new - onset
dyspnea , right
pleural effusion , and uncontrolled
hyperglycemia . -
pubmed
[ Characteristics of
blood aggregation in
human subjects of different age categories during normobaric interval hypo - oxytraining ] . -
pubmed
Blood aggregation was studied in
human subjects of different age groups given normobaric hypooxytraining . -
pubmed
The experiment was performed with participation of two groups of
volunteers : experienced
human subjects well - adapted to
hypoxia and young non - adapted subjects . -
pubmed
Two groups of the
human subjects displayed significantly different reactions to of
blood aggregation to the extreme factor ( NOT ) . -
pubmed
Interdisciplinary rehabilitation of a
patient with
Opitz C - syndrome and extensive
craniofacial malformation . -
pubmed
Time trends and risk factors for
diabetes mellitus in
cats presented to veterinary teaching hospitals . -
pubmed
Low intervertebral disc height in postmenopausal
women with
osteoporotic vertebral fractures compared to hormone - treated and untreated postmenopausal women and premenopausal women without
fractures . -
pubmed
OBJECTIVE : To assess the intervertebral disc height in postmenopausal
women with
osteoporotic vertebral fractures . -
pubmed
The disc height of the group of
women ( n = 38 ) with
osteoporotic vertebral fractures was compared to the disc heights of hormone - treated
women ( n = 47 ) , untreated postmenopausal
women ( n = 77 ) and another group of premenopausal
women ( n = 41 ) . -
pubmed
METHODS : From January 2001 to December 2005 , 17
HIV patients , with at least one previous episode of
VL who received
L - AMB as secondary prophylaxis for
VL , were included in the study . -
pubmed
Efficacy was measured as the proportion of
patients remaining free ( non -
relapse ) of
VL at different time points . -
pubmed
Prophylaxis with
L - AMB was well tolerated and only three
patients had a mild
impairment of renal function without requiring any change in treatment . -
pubmed
[ Comment on " Automated perimetry in
patients with primary
congenital glaucoma " ] . -
pubmed
We report a 17 - year - old
boy who was diagnosed as
autoimmune encephalitis with various neurological complications such as
hemiplegia ,
aphasia and
seizures . -
pubmed
We demonstrated the possibility of
steroid - sparing treatment with
tacrolimus for a
patient with
steroid - responsive
encephalitis . -
pubmed
Tacrolimus may be effective for selected
patients with recurrent
encephalitis in which an autoimmune mechanism is considered as the pathogenesis . -
pubmed
Fifteen years after transplantation , the
patient presented with
variceal bleeding , liver biopsy showed
nodular regenerative hyperplasia (
NRH ) . -
pubmed
Furthermore , a high index of suspicion with early detection of
NRH is crucial , as improvement seems only to occur in
patients with compensated
liver disease . -
pubmed
Inactivation of malignant tissue in
tumor - immune
rats . -
pubmed
PATIENTS AND METHODS : Charts of
patients treated from January 2004 to January 2006 were reviewed for choice of treatment ,
tumor response , toxicities and survival . -
pubmed
Early interruption of treatment due to toxicity or
patient 's refusal ( 42.5 vs. 15.6 , p=0.001 ) and
deaths within 30 days from last chemotherapy administration ( 22.5 % vs. 3.9 % , p=0.003 ) were significantly different . -
pubmed
F
patients may respond to chemotherapy but display higher rates of premature withdrawal and early
deaths compared to NF patients , with a shorter survival . -
pubmed
Sixty consecutive
patients suffering
epistaxis of local origin in an Accident and Emergency department in a District General Hospital were included in this study which was conducted over a 7 - month - period ( September - March ) . -
pubmed
Data collected included :
patient 's demographics , cause of
epistaxis , management plan , admission , in - patient stay and complications . -
pubmed
In the
patients ' group treated under the revised protocol , the total number of admissions was significantly reduced , by 73 % , ( P & lt ; 0.0001 ) , despite no significant change in the number of monthly
epistaxis referrals ( P & lt ; 0.0001 ) . -
pubmed
There was also a significant increase in the mean age of admitted
patients with
epistaxis ( P & lt ; 0.0001 ) , the admitted patients had a mean length of stay of 2.5 days . -
pubmed
RESULTS : We recorded 169
UTI in 76
patients ( 38
men/38
women , 33 % ) over a mean follow - up of 779.9+/-523.3 days . -
pubmed
OBJECTIVE : The aim of this study was to find an effective treatment for the genetic form of
diabetes that is present in some
Huntington ' s disease patients and in
Huntington ' s disease mouse models . -
pubmed
The treatment also improved motor function and extended the survival time of the
Huntington ' s disease mice . -
pubmed
We studied 192 postmenopausal
women with
low BMD with a mean age of 62.75 + /- 8.58 years . -
pubmed
Prevelance of
CD in postmenopausal
women with
low BMD ( 0.5 % ) did not differ from prevelance of
CD in normal healthy population ( 0.3 - 1 % ) . -
pubmed
Advantages of delaying the onset of rehabilitative reaching training in
rats with incomplete
spinal cord injury . -
pubmed
We have previously reported that rehabilitative reaching training initiated 4 days following an incomplete cervical
spinal cord injury (
SCI ) in adult
rats promotes plasticity and task - specific recovery . -
pubmed
The effects of psychological status of the
patients with digestive system
cancers on prognosis of the disease . -
pubmed
To assess the association between psychological status and prognosis of
patients with
digestive system cancer , epidemiological investigations were conducted in 2 periods to obtain information about the patients ' psychological status , survival time , and quality of life . -
pubmed
Despite important gaps in our knowledge regarding how phytochemicals interfere with cellular function in vivo , effective chemopreventive measures have shown that phytochemicals can be utilized to prevent
cancer , and possibly to treat
cancer patients as well . -
pubmed
PATIENTS AND METHODS : Among the
patients with genetically determined
enzymopathies 3
patients had
aminoacidopathies , and 11 had different types of
encephalopathies , from which 10 had
mitochondrial encephalomyopathy (
MEMP ) , and 1
patient had
hyperuricaemic encephalopathy . -
pubmed
Besides the mentioned 14
patients , 1 had
ceroid lipofuscinosis and another patient had
tuberous sclerosis . -
pubmed
Mitochondrial encephalo - myopathic (
MEMP ) group -- all the four
patients with
MEMP and
lactic acidosis showed focal hypoperfusion in the temporal region , while the perfusion was normal in the
COX deficient patient and in 2
Leigh ' s disease ( subacute necrotizing
encephalopathy )
patients . -
pubmed
In the remaining 1 Leigh 's
patient frontotemporal hypoperfusion was found . -
pubmed
In all
patients there were non specific structural abnormalities detected by MRI : cortical and subcortical
atrophy , and scattered
demyelination foci . -
pubmed
The
patient with
tuberous sclerosis showed bilateral
temporo - occipital hypoperfusion . -
pubmed
In the present article , we review the putative effects of
insulin resistance on EPCs , discuss the underlying mechanisms and highlight potential therapeutic manoeuvres which could improve vascular repair in
individuals with
insulin resistance . -
pubmed
Unlike
human blood monocytes , these
melanoma cells require no exogenous stimulation . -
pubmed
Patients were randomized either to primary ( p - PCI ) or to full - dose
tenecteplase before PCI ( f - PCI).The study end point was the composite of
death ,
cardiogenic shock , or
congestive heart failure at 90 days . -
pubmed
A study to determine the seroprevalence of
Dirofilaria immitis was carried out in feral
cats in Grenada . -
pubmed
immitis infection in feral cats coupled with the endemic nature of
heartworm disease in dogs in Grenada leads us to suggest the introduction of
heartworm prophylaxis in
cats . -
pubmed
CLINICAL PRESENTATION : A 45 - year - old
man presented to our institution with
subarachnoid hemorrhage secondary to a small distal basilar trunk
aneurysm . -
pubmed
We report a case of ipsilateral combination of
Galeazzi and Monteggia fractures in a ten - year - old
patient . -
pubmed
RESULTS : The group included 41
boys , 60 % with coronal or distal
hypospadias and 40 % with
mid - shaft hypospadias ( aged 6 months to 16 years , median : 3 years ) . -
pubmed
A 6 - year - old
boy presented with a diffuse mediastinal mass and received an open mediastinal biopsy for a definitive diagnosis , which led to the occurrence of massive
chylothorax postoperatively . -
pubmed
Tympanic membrane
wound healing in
rats assessed by transcriptome profiling . -
pubmed
Subsequent analysis was performed using Agilent 's 4 x 44 k whole
rat genome arrays ( 40 in total ) to assess
wound - healing gene expression over a 7 - day time period . -
pubmed
Solithromycin demonstrated potent in vitro activity against the NF54
strain of
P. - pubmed
berghei infection in
mice ,
solithromycin demonstrated a 100 % cure rate when administered as a dosage regimen of four doses of 100 mg / kg of
body weight , the same dose required for
artesunate or
chloroquine to achieve 100 % cure rates in this rodent
malaria model . -
pubmed
Dovyalis abyssinica might be a promising candidate for phytotherapy of
trypanosomiasis . -
pubmed
Patient preferences for coronary artery bypass graft surgery or percutaneous intervention in multivessel
coronary artery disease . -
pubmed
OBJECTIVES : Determine if
patients prefer multivessel percutaneous coronary intervention ( mv - PCI ) over coronary artery bypass graft surgery ( CABG ) for treatment of symptomatic
multivessel coronary artery disease ( mv -
CAD ) despite high 1 - year risk . -
pubmed
BACKGROUND :
Patient risk perception and preference for CABG or mv - PCI to treat medically refractory mv -
CAD are poorly understood . -
pubmed
METHODS : 585
patients and 31 physicians were presented standardized questionnaires with a hypothetical scenario describing
chest pain and medically refractory mv -
CAD . -
pubmed
A 22 - year - old
woman with features suggestive of
Cushing ' s syndrome was found to have
right adrenal mass on imaging studies . -
pubmed
Black
adenoma of the right adrenal cortex , a
pigmented adenoma consisting of compact cells with numerous pigments suggestive of melanin and lipofuscin was laproscopically removed from this
patient . -
pubmed
We report on the case of a
patient developing
biliary tract obstruction due to fibrous material in the common hepatic duct 15 years after pancreatoduodenectomy . -
pubmed
The
dengue human challenge model : has the time come to accept this challenge ? -
pubmed
Certain
N -( naphthalen-2 - yl ) acetamide and
N -( substituted phenyl ) acetamide bearing
quinolin-2 ( 1H )- one and
3,4 - dihydroquinolin-2 ( 1H )- one derivatives have been synthesized and evaluated in vitro for their antiproliferative activities against a panel of
human cancer cell lines including nasopharyngeal (
NPC - TW01 ) , lung
carcinoma (
H661 ) ,
hepatoma (
Hep3B ) ,
renal carcinoma (
A498 ) , and
gastric cancer (
MKN45 ) . -
pubmed
In addition , compound 18 demonstrated very specific
cytotoxicity against
human nasopharyngeal carcinoma (
NPC - TW01 ) cell lines with no detectable
cytotoxicity against peripheral blood mononuclear cells ( PBMCs ) at a concentration of up to 50 muM. -
pubmed
An opportunity for
cancer prevention during preadolescence and adolescence : stopping
human papillomavirus ( HPV )- related cancer through
HPV vaccination . -
pubmed
CONCLUSIONS : The results suggest that healthcare providers in rural areas can increase
HPV vaccine uptake and reduce
HPV - related
cancers by using a multifaceted approach to educating their patients within the context of the patients ' cultural values , geographic location , and economic situation . -
pubmed
Bariatric surgery has to be considered in the management of severely
obese adolescents when all conservative measures have been proven to be unresponsive . -
pubmed
Fiveteen years old
girl with
body mass index 42.2 kg / m(2 ) ,
hyperinsulinism ,
hyperandrogenism ,
amenorrhea ,
polycystic ovarian syndrome ,
hypertension with
left ventricular hypertrophy . -
pubmed
We can conclude that bariatric surgery should be considered for a minority of severely
obese adolescents under the supervision of a multidisciplinary pediatric team . -
pubmed
The increased surgical accuracy in robotic assistance could limit
postoperative complications rate in obese
adolescents . -
pubmed
METHODS : We report three cases of
patients with a bipartite atlas as a coincidental finding in a
trauma setting . -
pubmed
The
patients had no neurological symptoms relating to the
C1 abnormality , and no follow - up was performed . -
pubmed
Over - aggressive treatment of grade V
SAH patients . -
pubmed
In
patients with operable
esophageal cancer , there is evidence supporting the use of preoperative chemotherapy or preoperative chemoradiation . -
pubmed
The organism isolated from culture of the biopsy material was
Fonsecaea pedrosoi thus confirming our diagnosis of
cutaneous chromoblastomycosis . -
pubmed
Early changes of gene expression profiles in the
rat model of
arterial injury . -
pubmed
The purpose of the present study was to investigate the early alterations in arterial - wall gene expression after
balloon injury in the
rat carotid artery with focus on the induction of an inflammatory response . -
pubmed
MATERIALS AND METHODS : Twenty - four male
Sprague - Dawley rats were subjected to
injury of the left common carotid artery by using a 2 - F Fogarty catheter . -
pubmed
People with
type 2 Diabetes have an elevated risk for developing
cardiovascular disease (
CVD ) for which
dyslipidemia is the major contributor . -
pubmed
Altered autophagy induction by sera from pregnant
women with
pre - eclampsia : a case - control study . -
pubmed
We hypothesised that sera from
women with healthy pregnancies and
women with
pre - eclampsia differed in autophagy induction . -
pubmed
POPULATION : Twenty - four normotensive pregnant
women and 20
women with
pre - eclampsia . -
pubmed
RESULTS : Autophagy induction increased with gestational age in sera from normotensive
women ( P = 0.0045 ) , but not in
women with
pre - eclampsia . -
pubmed
In the presence of an autophagy inducer , the capacity for autophagy induction decreased with gestational age in sera from
women with
pre - eclampsia ( P = 0.0235 ) , but not from controls . -
pubmed
CONCLUSIONS : Sera from
women with
pre - eclampsia differ from normotensive women by their inability to induce autophagy as a function of gestational age . -
pubmed
Efficacy and safety of mavrilimumab in
Japanese subjects with
rheumatoid arthritis : findings from a Phase IIa study . -
pubmed
Our findings demonstrate that
caffeine can be combined with
OTP and the absorption of
C - CAF is inhibited in
mice , thus decreasing the
irritation effect of
caffeine . -
pubmed
Orthosiphon stamineus protects
Caenorhabditis elegans against
Staphylococcus aureus infection through immunomodulation . -
pubmed
CONCLUSION : PTLPs demonstrate capability in eradicating
C difficile in vitro , and with further development , may represent an organism - specific , microbiome - sparing therapy for
CDI . -
pubmed
Renal sparing surgery using focus ultracision harmonic scalpel in
patients with
bilateral wilms ' tumor : case report . -
pubmed
CASE REPORT : We describe a 3 year - old female
patient with bilateral
Wilms ' tumor arising in the central localisation of the right and foci in the left kidney enucleated successfully with a simple and comfortable renal preserving operative technique using Focus Ultracision Harmonic Scalpel . -
pubmed
A total of 24
RTT patients were assigned to
omega-3 PUFAs - containing
fish oil for 12 months in a randomized controlled study ( average
DHA and
EPA doses of 72.9 , and 117.1mg / kgb.w./day , respectively ) . -
pubmed
OBJECTIVES : The goal of this study was to compare cardiac output derived from the FloTrac / Vigileo system ( CO(FT ) ) with cardiac output measured by 3 - dimensional transesophageal echocardiography ( CO3D ) in
patients with severe
heart failure undergoing cardiac resynchronization therapy . -
pubmed
CONCLUSIONS : The FloTrac / Vigileo system is not accurate in
patients with
low cardiac output , especially those with a cardiac index<2.2 L / min / m(2 ) . -
pubmed
A total of 166 D -
IBS patients were randomly divided into four treatment groups , which included each combination of the examined frequencies and doses . -
pubmed
KIM is being piloted in a clinical trial for
prostate cancer patients treated with VMAT ( NCT01742403 ) . -
pubmed
EXPERIMENTAL DESIGN : The influence of coffee consumption on
patient and
tumor characteristics and disease - free survival was assessed in a population - based cohort of 1,090
patients with invasive primary
breast cancer in Sweden . -
pubmed
[ Efficacy and safety of
sugammadex (
Org 25969 ) in reversing deep
neuromuscular block induced by
rocuronium or
vecuronium in Japanese
patients ] . -
pubmed
BACKGROUND : Efficacy and safety of
sugammadex in reversing
neuromuscular block induced by
rocuronium or
vecuronium were investgated in Japanese
patients . -
pubmed
Twenty - five
subjects with
T2DM2 , 25 healthy controls , 25 subjects with
obesity , and 25 subjects with
T2DM combined with
obesity were included in the study . -
pubmed
RESULTS : 22,305
patients ( 1.5 % ) experienced a
UTI . -
pubmed
METHODS : The study group comprised 74 middle - aged
patients with chronic
AKP . -
pubmed
Toxicity of synthetic herbicides containing
2,4 - D and
MCPA moieties towards
Pseudomonas putida mt-2 and its response at the level of membrane
fatty acid composition . -
pubmed
A 42 - year - old
woman was referred , for adjuvant treatment , by an oncosurgeon ( outside our centre ) after a transhiatal oesophagectomy and gastric pull - up for middle one - third
squamous cell carcinoma of the oesophagus pT3N1M0 . -
pubmed
The
patient tolerated the treatment well and had partial
pain relief , and , in view of poor prognosis , was advised best supportive care . -
pubmed
Transplantation of Encapsulated Pancreatic Islets as a Treatment for
Patients with
Type 1 Diabetes Mellitus . -
pubmed
This review consists of three sections : introduction to islet transplantation , transplantation of encapsulated pancreatic islets as a treatment for
patients with
type 1 diabetes mellitus (
T1DM ) , and present challenges and future perspectives . -
pubmed
PURPOSE : This paper aimed to report a case of
Brown - Sequard - plus syndrome in an 8 - year - old
boy secondary to a
scissors stab wound at the craniocervical junction . -
pubmed
METHODS : The case study of an 8 - year - old
boy who was hospitalized because of a
scissors stab wound at the craniocervical junction . -
pubmed
The
patient developed
Brown - Sequard - plus syndrome on the left side of the body . -
pubmed
Influenza infection in
human host : challenges in making a better
influenza vaccine . -
pubmed
Human Bite - induced
Cellulitis Due to
Streptococcus pyogenes . -
pubmed
The rate of
infection after a
human bite is 10%-30 % . -
pubmed
The authors describe a 5 - year - old girl admitted to the emergency room with
cellulitis due to
S. - pubmed
pyogenes after
human bites . -
pubmed
She presented with
fever and
pain in her left arm , and her medical history revealed a
human bite by her cousin on the arm 3 days prior . -
pubmed
pyogenes may cause serious
wound infections following
human bites . -
pubmed
This case was first reported as
cellulitis due to
S. - pubmed
pyogenes after a
human bite . -
pubmed
The bioartificial ACL graft was subsequently implanted in a
swine ACL rupture model in place of the surgically removed normal ACL . -
pubmed
Bile deficiency induces changes in intestinal
glucose absorption in
mice . -
pubmed
The poor prognosis for
patients with
inflammatory breast cancer (
IBC ) compared to patients with other types of
breast cancers emphasizes the need to better understand the molecular underpinnings of this disease with the goal of developing effective targeted therapeutics . -
pubmed
Diet - induced
obesity increases the frequency of Pig - a mutant erythrocytes in male C57BL/6J
mice . -
pubmed
Obesity increases the risk of a number of
chronic diseases in
humans including several
cancers . -
pubmed
Pig - a mutant frequencies and micronucleus frequencies were determined in blood cells in two independent experiments in 30 - week old male
mice reared on either a high - fat diet ( 60 % calories from fat ) that exhibit an
obese phenotype or a normal - fat diet ( 10 % calories from fat ) that do not exhibit an
obese phenotype . -
pubmed
Lymphoepithelioma - like
carcinoma of breast - evaluation for
Epstein - Barr virus - encoded RNA ,
human papillomavirus , and markers of basal cell differentiation . -
pubmed
Analysis for in situ hybridization for
Epstein - Barr virus - encoded RNAs and
human papillomavirus DNA on paraffin - processed tissues was negative in all
tumors . -
pubmed
RESULT : Of the 39/252 ( 15.4 % ) ELBW
infants who developed
IH , those with early ( 59 % ) versus late ( 41 % ) repair were comparable in
birth weight ( 753 + - 158 versus 744 + - 131 g , p = 0.84 ) , gestation age ( 26 + - 2 versus 26.2 + - 2 weeks , p = 0.92 ) , with comparable rate of
broncopulmonary dysplasia ( 87 % versus 75 % , p = 0.41 ) , but early repair group had prolonged respiratory support ( 60.6 + - 28.6 versus 39 + - 30 days , p = 0.032 ) . -
pubmed
A Comparative Approach of
Tumor - Associated
Inflammation in
Mammary Cancer between
Humans and
Dogs . -
pubmed
It has been well established that the development of
mammary cancer , both in
humans and in
dogs , is associated with alterations in numbers and functions of immune cells at the sites of
tumor progression . -
pubmed
Indeed , recent studies in
human breast cancer and in
canine mammary tumors have identified a growing list of signaling molecules released by inflammatory cells that serve as effectors of their
tumor - promoting actions . -
pubmed
This review describes the intertwined signaling pathways shared by T - lymphocytic / macrophage infiltrates and important tissue biomarkers in both
human and
dog mammary
carcinogenesis . -
pubmed
We previously observed an increase in
arrhythmias during spontaneous prolonged
hypoglycemia in
patients with
T2DM . -
pubmed
Participants with
T2DM exhibited greater heterogeneity of repolarization during
hypoglycemia as demonstrated by T - wave symmetry and principal component analysis ratio compared with control participants . -
pubmed
Individuals with
T2DM demonstrate greater repolarization abnormalities for a given
hypoglycemic stimulus despite comparable sympathoadrenal responses . -
pubmed
METHODS : Thirty - eight
patients with a
major depressive disorder (
MDD ) and forty healthy matched controls were assessed with a ToM task using animated triangles . -
pubmed
RESULTS : Our findings show that 1 ) healthy female controls performed significantly stronger on the ToM task than female
MDD patients , 2 ) these performance differences were driven by attachment styles and 3 )
depression severity did not impact task performance . -
pubmed
Here , we describe establishment of a
human ovarian carcinoma cell line , which we term
WHIRC01 , from a patient - derived
mouse xenograft established from a chemorefractory
HGSOC patient who did not respond to
carboplatin and
paclitaxel therapy . -
pubmed
WHIRC01 represents a chemorefractory
human HGSOC cell line model with a comprehensive molecular profile to aid future investigations of drug resistance mechanisms and screening of chemotherapeutic agents . -
pubmed
Moreover ,
mice infected with the TgCDS1 mutant became fully resistant to challenge
infection with a hyper - virulent
strain of
T. - pubmed
aureus (
MRSA ) ; however , the commonly used drug
amoxicillin /
clavulanic acid was effective only against sensitive
strains . -
pubmed
Here , we report the case of a 2 - year - old
child who presented with severe
nutritional rickets associated with
seizure and
cardiomyopathy . -
pubmed
We present a case of
herpes zoster eruption occurring after PDT for
actinic keratoses in a
patient with
Non - Hodgkin Lymphoma (
NHL).</p> ; & lt;p><em>J Drugs Dermatol . -
pubmed
Patients :
Adults aged 45 years or older who had or were at risk for
atherosclerotic disease and were having noncardiac surgery . -
pubmed
Results : In
patients with prior PCI ,
aspirin reduced the risk for the primary outcome ( absolute risk reduction , 5.5 % [ 95 % CI , 0.4 % to 10.5 % ] ; hazard ratio [ HR ] , 0.50 [ CI , 0.26 to 0.95 ] ; P for interaction = 0.036 ) and for
myocardial infarction ( absolute risk reduction , 5.9 % [ CI , 1.0 % to 10.8 % ] ; HR , 0.44 [ CI , 0.22 to 0.87 ] ; P for interaction = 0.021 ) . -
pubmed
The effect on the composite of major and life - threatening
bleeding in
patients with prior PCI was uncertain ( absolute risk increase , 1.3 % [ CI , -2.6 % to 5.2 % ] ) . -
pubmed
Objectives : Cervical nerves block can not be performed on some
patients because of the risk of phrenic nerve
paralysis . -
pubmed
Case report : We present the case of a 62 - year - old
woman with clavicular
fracture . -
pubmed
Conclusions : We can perform selective supraclavicular nerve blocks for clavicular
fracture surgery of
patients who have bilateral
pneumothorax . -
pubmed
Finally , the implications of these processes in developing strategies to prolong the
cancer - free
human lifespan are discussed . -
pubmed
The Potential Effects of New Stent Platforms for Coronary Revascularization in
Patients With
Diabetes . -
pubmed
Coronary artery disease in
patients with
diabetes mellitus (
DM ) is characterized by extensive
atherosclerosis , longer lesions , and diffuse distal disease . -
pubmed
Traditionally , coronary artery bypass grafting ( CABG ) has been regarded as more effective than percutaneous coronary intervention ( PCI ) in
patients with
DM , likely because of more complete revascularization and protection against
disease progression in the bypass segment . -
pubmed
Revascularization with balloon angioplasty , bare - metal stents , and first - generation drug - eluting stents have all been shown to be inferior to CABG in
patients with
DM . -
pubmed
The use of thinner struts , biocompatible polymer coating , and newer antiproliferative agents have improved the rates of cardiovascular events in
patients with
DM revascularized percutaneously . -
pubmed
Since the publication of current guidelines , new studies suggested acceptable outcomes in
patients with
DM revascularized with second - generation drug - eluting stents , even though these conclusions are drawn from small subgroup analyses or nonrandomized studies . -
pubmed
Therefore , contemporary revascularization in
patients with
DM with multivessel
coronary artery disease should involve a multidisciplinary approach , in which interventional cardiologists and cardiac surgeons involve their patients to individualize treatment choices , and balance the risks and effectiveness of each modality . -
pubmed
Cardiovascular phenotype and prognosis of
patients with
heart failure induced by
cancer therapy . -
pubmed
OBJECTIVE : This study compared the clinical features , cardiac structure and function evaluated by echocardiography , cardiopulmonary response to exercise and long - term clinical outcomes between
patients with
heart failure (
HF ) induced by
cancer therapy ( CTHF ) and
heart failure not induced by
cancer therapy ( NCTHF ) . -
pubmed
METHODS : We evaluated 75
patients with
CTHF and 894 with NCTHF who underwent clinically indicated cardiopulmonary exercise testing , and followed these
individuals for a median of 4.5 ( 3.0 - 5.8 ) years , during which 187
deaths and 256 composite events (
death , heart transplantation and left ventricular ( LV ) assistant device implantation ) occurred . -
pubmed
RESULTS : Compared with NCTHF ,
patients with
CTHF were younger , with lower prevalence of cardiovascular comorbidities , higher LV ejection fraction ( LVEF ) , but similar global longitudinal
strain . -
pubmed
Autophagy induced by ionizing radiation promotes cell
death over survival in
human colorectal cancer cells . -
pubmed
Reduced activity and connectivity of left amygdala in
patients with
schizophrenia treated with
clozapine or
olanzapine . -
pubmed
Obsessive - compulsive symptoms ( OCS ) in
patients with
schizophrenia are a common co - occurring condition , often associated with additional impairments . -
pubmed
A subgroup of these
patients develops
OCS during treatment with second - generation antipsychotics ( SGAs ) , most importantly
clozapine and
olanzapine . -
pubmed
Effect of
progesterone administration on the prognosis of
patients with severe
traumatic brain injury : a meta - analysis of randomized clinical trials . -
pubmed
Methods : A systematic literature search of PubMed , Embase , and Cochrane databases and the Web of Science ( from establishment of each to September 1 , 2018 ) was performed to identify original RCTs that evaluated the associations between
progesterone treatment and the prognosis of
patients with severe
TBI . -
pubmed
Results : Eight RCTs enrolling 2,251
patients with severe
TBI were included . -
pubmed
METHODS : A prospective cohort study of 106
patients who were switched to this dual regimen from April 2014 to December 2017 because of
renal and bone toxicity , intolerance , or physician 's decision was conducted . -
pubmed
Six
patients presented with metastatic foci ( five to the liver and one to the lung ) , while
lymphadenopathy was observed in five
patients ( 20 % ) . -
pubmed
Impact of pre - existing
dengue immunity on
human antibody and memory B cell responses to
Zika . -
pubmed
Little is known about enduring memory B cell ( MBC ) responses to
Zika virus (
ZIKV ) and their relationship with circulating antibodies . -
pubmed
Here we comprehensively assess MBC frequency and specificity alongside serum binding and neutralizing antibody responses to
ZIKV ~2 weeks and ~8 months postinfection in 31 pediatric subjects with 0 , 1 or & gt;1 prior
infections with the related
dengue virus (
DENV ) . -
pubmed
ZIKV infection elicits a robust type - specific MBC response , and the majority of late convalescent anti -
ZIKV serum neutralizing activity is attributable to
ZIKV - specific antibodies . -
pubmed
The number of prior
DENV infections does not influence type - specific or cross - reactive MBC responses , although
ZIKV has the highest cross - reactivity with
DENV3 . -
pubmed
BACKGROUND : Treatment adherence and persistence are crucial to achieve glycemic control in
patients with
type 2 diabetes (
T2D ) . -
pubmed
Changes in A1c and
body weight from baseline through 6 months were assessed for all
patients ; early response was defined by & gt ; 1 % reduction in A1c and & gt ; 3 % reduction in
body weight within 3 - 6 months . -
pubmed
RESULTS : Among 8,329 identified
patients , 33.3 % and 31.2 % experienced early response as indicated by reductions in A1c & gt ; 1 % point and in
body weight & gt ; 3 % from baseline , respectively . -
pubmed
Significantly higher proportions ( P & lt ; 0.001 ) of early responders in both reduced A1c and
body weight were adherent over 18 months compared with
patients without an early response ( A1c : 45.0 % vs. 37.1 % ;
body weight : 43.3 % vs. 38.0 % ) . -
pubmed
Significantly lower proportions ( P & lt ; 0.001 ) of early responders discontinued over 18 months compared with
patients without an early response ( A1c : 61.4 % vs. 67.9 % ;
body weight : 61.9 % vs. 67.5 % ) . -
pubmed
Glyphosate , a widely used herbicide , has been classified as probably carcinogenic to
humans by the International Agency for Research on
Cancer ( IARC ) . -
pubmed
These
patients have
pituitary adenomas that are thought to be mixed lactotrophs and somatotrophs . -
pubmed
CASE DESCRIPTION : The
patient 's mother , diagnosed with
acrogigantism at 21 months , underwent
pituitary tumor excision at 24 months . -
pubmed
The pathophysiological mechanisms of
cognitive and gait disturbances in
subjects with
normal - pressure hydrocephalus (
NPH ) are still unclear . -
pubmed
Cholinergic and other neurotransmitter abnormalities have been reported in
animal models of
NPH . -
pubmed
The objective of this study was to evaluate the short latency afferent inhibition ( SAI ) , a transcranial magnetic stimulation protocol which gives the possibility to test an inhibitory cholinergic circuit in the
human brain , in
subjects with
idiopathic NPH (
iNPH ) . -
pubmed
We applied SAI technique in twenty
iNPH patients before ventricular shunt surgery . -
pubmed
A significant reduction of the SAI ( p = 0.016 ) , associated with a less pronounced decrease of the resting motor threshold and the short latency intracortical inhibition to paired stimulation , were observed in
patients with
iNPH at baseline evaluation . -
pubmed
These findings suggest that the impairment of cholinergic neurons markedly contributes to
cognitive decline and
gait impairment in
subjects with
iNPH . -
pubmed
A prolific biofilm forming
strain (
Staphylococcus lentus ) , possessing high tolerance ( > 1,000 microg ml-1 ) to dissolved
copper ions (
Cu ++ ) was isolated from
titanium coupons exposed in the coastal waters of Kalpakkam , east coast of India . -
pubmed
It is defined as a
triad of
microangiopathic hemolytic anemia ,
thrombocytopenia and
renal insufficiency associated with Shiga toxin - producing
Escherichia coli . -
pubmed
Case report : We report the case of a one - year - old Caucasian girl , without significant medical history , who was found to have stool culture with positive enteropathogenic
Escherichia coli after an episode of
diarrhea . -
pubmed
The role of structured physiotherapy in treating
patients with
atraumatic shoulder instability : Medium term results from a case series . -
pubmed
Patients with
posterior instability demonstrated better results compared with other groups ( OSIS change , p = 0.025 ; WOSI change , p = 0.060 ) . -
pubmed
Vitamin D deficiency is common in
patients with
primary hyperparathyroidism . -
pubmed
Comparison of
melphalan- And
busulfan - based myeloablative conditioning in
children undergoing allogeneic transplantation for
acute myeloid leukemia or
myelodysplasia . -
pubmed
BACKGROUND : The optimal conditioning regimen for alloHCT in
children with
myeloid malignancies remains undefined . -
pubmed
PROCEDURE : We performed a retrospective review of
children undergoing alloHCT for
AML and
MDS over a 10 - year period ( 2008 - 2018 ) at our institution , comparing the outcomes of
recipients of either a myeloablative
busulfan- or reduced toxicity mel /
thio - based conditioning regimen . -
pubmed
RESULTS : A total of 49
patients underwent alloHCT for
AML /
MDS ( mel / thio , N = 21 ;
busulfan , N = 28 ) . -
pubmed
One
patient in each group died from
TRM . -
pubmed
Relapse incidence was comparable ( mel / thio-29 % vs
busulfan-32 % ) ; however ,
relapse occurred significantly later in
recipients of
mel /
thio conditioning ( median d + 396 vs d + 137 ; P = .01 ) . -
pubmed
CONCLUSION : In our single institution , when compared to myeloablative
busulfan - based conditioning , use of a mel /
thio - based reduced
toxicity regimen resulted in comparable outcomes , despite higher risk
patient and disease characteristics . -
pubmed
Forty - five
patients received > = 1 doses of losatuxizumab vedotin ( 13 colon , 6
non - small cell lung cancer , 5 head and neck [ HNC ] , 5
glioblastoma multiforme , 2 breast , 14 other ) . -
pubmed
Multivessel versus culprit - only PCI in
STEMI patients with
multivessel disease : meta - analysis of randomized controlled trials . -
pubmed
AIMS : To perform a pairwise meta - analysis of randomized controlled trials ( RCTs ) comparing multivessel percutaneous coronary intervention ( PCI ) and culprit vessel - only PCI in
ST - elevation myocardial infarction (
STEMI )
patients without
cardiogenic shock . -
pubmed
METHODS : We searched MEDLINE , Cochrane Central Register of Controlled Trials , and Embase for RCTs comparing multivessel PCI with culprit vessel - only PCI in
STEMI patients without
cardiogenic shock and
multivessel coronary artery disease . -
pubmed
In total , 523 ( 8.3 % ) of 6314
patients suffered the combined primary endpoint of
death or non - fatal
reinfarction . -
pubmed
CONCLUSIONS : In
STEMI patients without
cardiogenic shock multivessel PCI reduced the risk of
death or non - fatal
reinfarction compared to culprit vessel - only PCI . -
pubmed
No
cytotoxicity is found for cubic and spherical hydrogels upon their interactions with
human cancer cells for various time intervals . -
pubmed
METHODS : The 98
patients with
leukemia in our hospital were divided into two groups according to the diagnosis of
patients :
ALL group ( 56 cases ) and
ANLL group ( 42 cases ) . -
pubmed
The related risk factors ( all P<0.05 ) influencing the survival of
patients with
ALL were confirmed by multivariate logistic analysis . -
pubmed
Disrupted
potassium ion homeostasis in ciliary muscle in negative lens - induced
myopia in
Guinea pigs . -
pubmed
In the present study , right eyes of the
animals in LIM group were covered with -6.0 D lenses to induce
myopia . -
pubmed
Although not confined to
patients who are in their first or second decades of life ,
ameloblastic fibromas most often arise in this population . -
pubmed
CLINICAL SIGNIFICANCE : We might be missing early diagnosis of
ameloblastic fibroma and other significant
orofacial neoplasms in
patients who are nonverbal or nondescriptive such as those with
autism . -
pubmed
Reader response : Outcomes of
patients with
stroke treated with thrombolysis according to prestroke Rankin Scale scores . -
pubmed
Exploration of biomarkers to predict clinical improvement of
atopic dermatitis in
patients treated with
dupilumab : A study protocol . -
pubmed
However , no blood / serum biomarkers are known to predict good or poor outcome in
patients with
AD treated with dupilumab . -
pubmed
METHODS :
Patients are at least 18 years of age and have moderate - to - severe
AD with
Eczema Area and Severity Index ( EASI ) > = 16 , Investigator 's Global Assessment > =3 , and body surface area > = 10 % . -
pubmed
Comparison of the efficacy and safety of biological agents in
patients with systemic
juvenile idiopathic arthritis : A Bayesian network meta - analysis of randomized controlled trials . -
pubmed
OBJECTIVE : To assess the relative efficacy and safety of biological agents in
patients with
systemic juvenile idiopathic arthritis (
sJIA ) . -
pubmed
MATERIALS AND METHODS : We performed a Bayesian network meta - analysis to combine direct and indirect evidence from randomized controlled trials ( RCTs ) to examine the efficacy and safety of
canakinumab , anakinra , tocilizumab , and rilonacept in
patients with
sJIA . -
pubmed
Biopsy specimens of
patients undergoing
epilepsy surgery for
seizure relief provide unique insights into the impact of promoter SNPs on corresponding mRNA expression . -
pubmed
The present data suggest systematic analyses in
human hippocampal tissue as a useful approach to unravel the impact of
epilepsy candidate SNPs on associated gene expression . -
pubmed
To investigate the effects of dietary
isomaltooligosaccharide ( IMO ) levels on the gut microbiota , immune function of sows , and the
diarrhea rate of their offspring , 120 multiparous gestating
pig improvement company ( PIC ) sows with similar body conditions were selected and fed 1 of 6 diets : a basal diet with no supplement ( control , CON ) , or a diet supplemented with 2.5 g / kg , 5.0 g / kg , 10.0 g / kg , 20.0 g / kg , or 40.0 g / kg IMO ( IMO1 , IMO2 , IMO3 , IMO4 , or IMO5 group , respectively ) . -
pubmed
METHODS : Medical records of
children referred for primary
headache to the pediatric neurology clinic at Bnai Zion Medical Center from 2008 to 2017 were assessed . -
pubmed
Children in the
migraine group used more analgesic treatments to stop the
headache attacks compared with the
tension - type headache group ( 50 % vs 38 % , P = .001 ) . -
pubmed
Patients diagnosed with
tension - type headache reported having more emotional difficulties ( P = .001 ) . -
pubmed
No significant differences were found in
headache characteristics ( ie , location , sidedness , character ) , frequency , or intensity between the younger
children ( ages 6 - 11 ) and the adolescents ( ages 12 - 18 ) within either the
tension - type headache or
migraine groups . -
pubmed
METHODS : Fifty - four
adults with
gingivitis /
periodontitis were randomly assigned to 1X ST266 or diluted 0.3X ST266 or saline topically applied on facial / lingual gingiva ( 20muL / tooth ) . -
pubmed
CONCLUSIONS : In this " first in
human oral cavity " study , topical ST266 was safe and effective in reducing
gingival inflammation in 6 weeks . -
pubmed
Pathogenetic role of no - reflow phenomenon in experimental
subarachnoid hemorrhage in
dogs . -
pubmed
To study this problem , we carried out the following experiment in
dogs :
SAH was induced by withdrawing a needle previously inserted into the internal carotid artery through a small craniectomy in the lateral base of the skull . -
pubmed
The 32 episodes of
SAH thus induced yielded two basic patterns of ICP changes which simulated those previously reported with
human SAH . -
pubmed
Mouse profile and
dog emesis screens were performed , and the activity of various N - substituted derivatives and their
esters was evaluated and compared to the parent compounds . -
pubmed
[ Lethal
infection with BCG in thymectomized
mice ] . -
pubmed
Investigations carried out on CBA
mice demonstrated that adult
mice to which mycobacteria BCG were injected intravenously 12 months after thymectomy ( in a dose of 2 mg for a period of 2 1/2 months ) died of disseminated
BCG infection against the background of
depression of
hypersensitivity of delayed type . -
pubmed
The
chloride - dependent
depression by
GABA in the
frog spinal cord . -
pubmed
To evaluate the antihypertensive and hormonal effects of oral
magnesium supplementation , 17
inpatients with untreated , uncomplicated mild - to - moderate
essential hypertension (
EH ) and 8 age - matched normotensive controls ( controls ) were given
MgO orally 3 times a day at a daily dose of 1.0 g ( 0.6 g per day as
Mg ) for a period of 2 weeks . -
pubmed
suum in their lungs developed more severe
pneumonia and
septicaemia than did parasite - free
mice . -
pubmed
multocida as compared with a toxin - producing
strain of
P. - pubmed
multocida , possibly due to the higher spontaneous pathogenicity of the non - toxigenic
strain of
P. - pubmed
This paper describes the use of a nasal mask to deliver intermittent positive pressure ventilation to treat chronic
respiratory failure in one
patient with severe
kyphoscoliosis . -
pubmed
Intermittent nasal ventilation is a safe and effective ventilatory support modality for some
patients with hypercapnic
respiratory failure . -
pubmed
Intracranial tuberculosis in
children : CT appearance and clinical outcome . -
pubmed
Of 7
patients with
ventriculomegaly , 3 required a ventricular shunt and 2 had spontaneous resolution of
ventricular dilatation . -
pubmed
Four
children with
ventriculomegaly were moderately or severely retarded , one had
cognitive dysfunction , and one was neurologically normal . -
pubmed
Four of six
children with
tuberculoma also had
infarction and/or
ventriculomegaly ; of these four
children , three were moderately or severely retarded . -
pubmed
Two
patients with
tuberculoma as the only
intracranial abnormality had complete resolution of the
granuloma with normal neurologic outcome following antituberculous therapy . -
pubmed
The four
children with large vessel
infarction also had
ventriculomegaly ; three had poor clinical outcome . -
pubmed
The induction of
chromosome aberrations in
human peripheral blood lymphocytes is still the most useful dosimetry system for accidental whole - body irradiation ; however , in the case of a very large number of casualties the micronuclei technique might provide advantages . -
pubmed
Because the National
Cholesterol Education Program guidelines suggest that levels of total serum
cholesterol less than 5.17 mmol / liter ( 200 mg / dl ) are " desirable , " we performed a retrospective observational analysis to determine the prevalence of
coronary artery disease (
CAD ) in
patients with total
cholesterol less than 5.17 mmol / liter ( 200 mg / dl ) and the prevalence of total
cholesterol less than 5.17 mmol / liter ( 200 mg / dl ) in
patients with
CAD by angiography . -
pubmed
Survey of
Actinobacillus ( Haemophilus ) pleuropneumoniae infection in
swine by different methods . -
pubmed
Lung and serum samples from
pigs that died or were emergency - slaughtered in a pooled , conventional fattening herd were examined to survey
Actinobacillus pleuro - pneumoniae infection and to compare the sensitivity of different testing methods . -
pubmed
This study was designed to determine whether blood pressure reduction , per se , causes adverse effects on cognitive and behavioral function in elderly
hypertensive patients . -
pubmed
Men with mild - to - moderate
diastolic hypertension who had passed their 60th birthday were entered into the trial . -
pubmed
We conclude that blood pressure reduction , per se , does not adversely affect cognitive and behavioral function in elderly
hypertensive patients and that antihypertensive treatment is safe and effective in these
patients . -
pubmed
Three chromosome - specific repetitive probes labeled with either
amino acetyl fluorene (
AAF ) ,
mercury , or
biotin were hybridized simultaneously to metaphase chromosomes prepared from
human blood lymphocytes or to interphase
tumor nuclei . -
pubmed
Three - color in situ hybridization was applied to the study of numerical
chromosome abnormalities as occur in
human solid tumors . -
pubmed
Multifactorial
hamster respiratory carcinogenesis with interdependent effects of cannula - induced mucosal wounding , saline ,
ferric oxide ,
benzo [ a ] pyrene and
N - methyl - N - nitrosourea . -
pubmed
Tracheal cancers ( in situ or invasive
carcinomas ) were seen only in those
hamsters which had received repeated
ITC and one or both carcinogens . -
pubmed
The
cancer latency was shortest and the incidence of tracheal ( 50 % ) and main - stem bronchial ( 21 % )
cancers highest in
hamsters given
MNU and repeated
ITC with BP -
Fe2O3 - saline . -
pubmed
A group of 250
patients with
rheumatoid arthritis were investigated to evaluate the neurologic status with respect to the degree of instability in the proximal cervical spine . -
pubmed
Antibodies reactive with heterologous neural tissue were detected by indirect immunofluorescence microscopy in the sera of 17 of 34
patients with
retinitis pigmentosa , one of 30 normal control sera , and a variable percentage of sera derived from subjects with diverse ocular and
neurological diseases . -
pubmed
These antibodies were also found both in disease - free first degree relatives and in spouses of
patients with
retinitis pigmentosa . -
pubmed
Eleven
patients with
Legg - Calve - Perthes disease (
LCP ) were examined ultrasonographically for their
femoral head deformity . -
pubmed
However , neither thymic nor other types of
leukemias were induced in these
rats . -
pubmed
Continuous administration of NPU to the
rats successfully induced 9
thymic lymphomas in the grafted thymuses . -
pubmed
The present results from these 2 experiments strongly suggested that
NPU - induced
rat thymic lymphomas originate from intrathymic cells but not from bone marrow cells . -
pubmed
A previously developed in vitro method using
human lymphocytes and a
murine microsomal drug metabolizing system has been used to examine
toxicity due to
acetaminophen (
APAP ) ,
sulfonamide antibiotics and aromatic anticonvulsants . -
pubmed
Lymphocytes from a
glutathione synthetase - deficient patient exhibited markedly enhanced toxicity to
APAP exceeding the 95 % CL of 10 control
subjects over a concentration range of 10 to 1000 micrograms / ml . -
pubmed
Experimental
lathyrism :
exostoses and
aneurysmal - like bone cysts of the mandible in the
rat . -
pubmed
The effect of chronic
lathyrism on the mandible of the
rat was studied . -
pubmed
Histopathology of the experimental
cysts had some points in common with the
human aneurysmal bone cyst . -
pubmed
[
Acute adult leukemia : experience with 41
patients ] . -
pubmed
[ Treatment with
erythromycin of experimental
legionellosis in
guinea pigs infected by aerosol ] . -
pubmed
The infectious
strain L. - pubmed
pneumophila serogroup 1 Philadelphia ( ATCC 33152 ) was cultured on
charcoal dialysed
yeast extract agar medium ( CDYE agar ) which produces more virulent
strains than those grown on classical agar media . -
pubmed
Toxicity and
mutagenicity tests of 4 anti -
cancer drugs in cultured
Chinese hamster cells . -
pubmed
We describe an elderly
woman presenting acutely with
tophus formation mimicking
infection , in whom diuretic therapy was responsible for
her disease . -
pubmed
75 % of the
patients who developed
septicemia within the first three days of life and 60 % of all neonates with
septicemia or
meningitis could be identified by an elevated I / T - ratio , the most sensitive leukocyte count . -
pubmed
Thrombocytopenia was observed in only 33 % of the
patients . -
pubmed
Pulmonary embolism and
deep venous thrombosis in burned
patients . -
pubmed
The effect and
toxicities of
Cis - containing combination chemotherapy were tested in 28
patients with
primary lung cancer . -
pubmed
In addition to these drugs ,
patients with
squamous cell cancer were treated with continuous subcutaneous infusion of 4 mg / m2
Peplomycin for 5 days and one shot i.v . -
pubmed
Patients with
adeno - and large cell cancer were treated with 30 mg / m2
Adriamycin and 4 mg
MMC , while
patients with
small cell cancer were given 150 mg / m2
VP-16 p.o . -
pubmed
Interstitial pneumonitis was observed in 40 % of
patients with
squamous cell cancer . -
pubmed
Two
patients with
adenocarcinoma died within 3 weeks after treatment due to
embolism of the abdominal aorta and
myocardial infarction probably caused by treatment with
Adriamycin . -
pubmed
Investigations were made on 113
patients suffering from
CFS . -
pubmed
[ Characteristics of the antigenic composition of the cells of
intra - and interspecific hybrids of
murine hepatoma XXIIa ] . -
pubmed
Hybrids of cultivated
mouse hepatoma XXIIA cells were studied for the presence of species - specificity antigens . -
pubmed
The cells of
MGXXIIA hepatoma , clone culture of L
mouse fibroblasters and
RJK hamster cells were used as parental cells . -
pubmed
Bone mineral density in
patients with
prostatic cancer treated with orchidectomy and with
estrogens . -
pubmed
The
patients were free from
metastases during the entire observation period . -
pubmed
To study the role of T cells in
diffuse panbronchiolitis (
DPB ) , we investigated T - cell subsets in bronchoalveolar lavage fluid ( BALF ) or 33
patients with
DPB , nine
patients with
bronchiectasis , and 20 healthy volunteers . -
pubmed
BALF from
DPB patients contained a higher percentage of neutrophils than that from
patients with
bronchiectasis or healthy volunteers , whereas the percentage of lymphocytes was similar in the three groups . -
pubmed
We describe an analysis of early B cell development in
mice with
X linked immunodeficiency ( Xid ) . -
pubmed
Since 1986 , the authors have implanted 11 subcutaneous infusion ports in nine
patients with
hemophilia . -
pubmed
There was a total of 6
infections ( 3
wound and 3 urinary tract ) in 6
patients among the 48 receiving
cefazolin ( 12.5 % ) , whereas no
infections were observed among the 54
patients who received
cefonicid . -
pubmed
METHODS : For 357
patients with
primary open - angle glaucoma , the optic disk was morphometrically analyzed , and the intraocular pressure was measured in 24 - hour profiles . -
pubmed
Epigastric island flaps were elevated 3 , 6 and 12 weeks after induction of
DM in
rats . -
pubmed
In seven
patients who had
dyspnea the biopsies were done in erect or semi - erect sitting positions . -
pubmed
Seroprevalences of Toxoplasma ,
malaria ,
rubella , cytomegalovirus ,
HIV and
treponemal infections among pregnant women in Cotonou , Republic of Benin . -
pubmed
Seroprevalences for
toxoplasmosis ,
malaria ,
rubella ,
cytomegalovirus ,
HIV and
treponemal infections were evaluated among 211 pregnant women residing in the Cotonou area , Republic of Benin . -
pubmed
Routine serological screening should be recommended in young age and in pregnancy for
rubella , only in pregnant women for
HIV and
toxoplasma infections , in order to control their possible consequences on women and newborns . -
pubmed
We studied the effect of 12 - 36 min of global
ischemia followed by 36 min of reperfusion in Langendorff perfused
rabbit hearts ( n = 26 ) . -
pubmed
Evidence of qualitatively altered nociception in
patients with
fibromyalgia . -
pubmed
OBJECTIVE : To investigate the perception of
pain in tender muscles of
patients with
fibromyalgia . -
pubmed
METHODS : Twenty - five
women with
fibromyalgia and 25 healthy
women were examined . -
pubmed
Subjects then recorded their response to induced
pain on a visual analog scale . -
pubmed
CONCLUSION : This study demonstrates that nociception is qualitatively altered in
patients with
fibromyalgia , which is consistent with recent findings in other
patients with
tender muscles . -
pubmed
[ Thrombocyto- and
coagulopathies in
patients with
diabetic glomerulosclerosis and
chronic glomerulonephritis ] . -
pubmed
In this study we have devised a simple and robust PCR strategy to detect a wide range of viruses ,
bacteria , and parasites , all of which are capable of causing
aseptic meningitis and
encephalitis . -
pubmed
OBJECTIVE : To evaluate the indications , techniques and outcome of organ - preserving
tumour enucleation in
patients with bilateral
testicular germ cell tumours (
BTGCT ) rather than standard bilateral radical orchidectomy which results in
loss of fertility and a lifelong requirement for
androgen replacement . -
pubmed
PATIENTS AND METHODS : In 13
patients with
BTGCT of 6 - 30 mm in diameter , the
tumours were enucleated under cold
ischaemia after inguinal testicular exploration , and biopsies of the
tumour bed and the peripheral parenchyma were taken . -
pubmed
Six of the 13
patients underwent testicular radiation ( 20 Gy ) for
carcinoma in situ ( CIS ) and five
patients had adjuvant local therapy . -
pubmed
RESULTS : The median follow - up was 62 months ( range 14 - 163 ) and the 13
patients are currently free of disease ; one
patient had local
recurrence 9 months after
tumour enucleation but after orchidectomy the
patient is free of disease after a follow - up of 156 months . -
pubmed
CONCLUSIONS : These results suggest that organ - sparing surgery in
patients with
BTGCT represents a new therapeutic approach with endocrinological and psychological advantages . -
pubmed
the
tumour is organ - confined with no infiltration of the rete testis , multiple biopsies of the
tumour bed and peripheral parenchyma should be taken , any associated
CIS treated by radiation therapy , and
patients must be followed closely . -
pubmed
The relative activity of
N -( beta - D - glucopyranosyl ) nicotinic acid to
nicotinic acid in
rats was 1/2.3 , 1/2.2 , 1/1.0 , and 1/1.7 as indices of the body
weight gain , food intake , blood
NAD content , and the increased urinary excretion of
niacin and its metabolites , respectively . -
pubmed
Archival biopsy specimens of
oral dysplasia of squamous cell carcinoma from 64
patients were analysed immunohistochemically . -
pubmed
Malignant cells of
patients with
cutaneous T cell lymphoma (
CTCL ) are of monoclonal origin and of the CD4+/CD45RO+ subset . -
pubmed
A 53 - year - old
man presented a
melanotic lung tumor which was based in the bronchus of the left lower lobe and closed the left main bronchus . -
pubmed
In recent years , several gene therapy procedures making use of
retroviral vectors that selectively target
HIV susceptible cells have been proposed in order to interfere with
HIV productive infection . -
pubmed
METHODS :
Patients ( n = 84 ) with initial locally advanced
rectal cancer ( uT3 / uT4 ) undergoing R0 resection were investigated after preoperative treatment that combined radiotherapy up to 45 Gy with two cycles of chemotherapy ( 5 - FU and
leucovorin on d 1 - 5 and 22 - 28 ) . -
pubmed
We reported a case of a
thrombosis of the retinal and central artery and vein in a 44 - year - old
patient , with
high - grade T - cell lymphoma . -
pubmed
BACKGROUND : The
Irukandji syndrome is a group of delayed ( 10 - 40 mins , mean 30 mins ) severe systemic symptoms occurring after an initial mild skin
sting by small carybdeid ( box ) jellyfish including
Carukia barnesi , known colloquially as the ' Irukandji ' . -
pubmed
In untreated
rats , echocardiography revealed significant ( P<0.001 )
LV dilatation and
systolic dysfunction compared with sham . -
pubmed
Fluoroquinolones have been associated with
peripheral sensory disorders and
weakness , especially in
patients with underlying
myasthenia gravis or
myasthenia - like Eaton - Lambert syndrome . -
pubmed
We report a case of diffuse
weakness due to a demyelinating
polyneuropathy that began after initiation of
trovafloxacin in a
patient without an underlying
neurologic disorder . -
pubmed
Midazolam as a first - line agent for
status epilepticus in
children . -
pubmed
However ,
midazolam as a first - line agent for
status epilepticus in
children has not been fully investigated . -
pubmed
Intravenous
midazolam was used for
status epilepticus in 27
children ( 38
convulsive episodes ) from January 1997 to December 1999 in our hospital . -
pubmed
Among them , 10
patients ( 16
convulsive episodes ) were treated with intravenous
midazolam as a first - line agent . -
pubmed
Midazolam seems to be effective and safe as a first - line therapy for
status epilepticus in
children . -
pubmed
BACKGROUND : Successful pregnancies after conservative
progestin treatment to young
women with endometrial
carcinoma have recently been reported . -
pubmed
CASE : A 28 - year - old
woman with
endometrial carcinoma received conservative treatment with high - dose
medroxyprogesterone acetate (
MPA ) and then conceived . -
pubmed
METHODS : The Platelet IIb / IIIa in
Unstable Angina : Receptor Suppression Using Integrilin Theraphy Trial ( PURSUIT ) enrolled 10,948
patients with non - ST - segment elevation
acute coronary syndromes , including 585 in Latin America and 4358 in North America . -
pubmed
METHODS : Twenty - one
patients with
PNP were categorized as mucosal dominant and mucocutaneous types based on clinical information . -
pubmed
We analyzed the T - cell subsets in 28
patients with stable
atopic asthma and 13 normal control subjects before and after 2 wk of treatment with
prednisolone , 20 mg / d , or placebo in a randomized , double - blind , parallel group study . -
pubmed
Products such as the tooth gel evaluated in this study may benefit
dogs with
xerostomia or other clinical conditions causing decreased saliva production . -
pubmed
A 67 - year - old
woman with
anorexia and
weight loss was referred to our hospital with a diagnosis of
type 4 gastric cancer . -
pubmed
Successful attempts at immunological
cancer prevention in
HER-2 / neu transgenic mice are described as an example . -
pubmed
Although the very high rate of
mammary carcinoma prevention in
mice has generated enthusiasm , it should not be forgotten that such treatments , when administered to healthy
humans at risk of
cancer , may carry the risk of inducing autoimmunity . -
pubmed
A 6 - wk - old
child with
FHL is presented . -
pubmed
Atherosclerotic burden in coronary and peripheral arteries in
patients with first clinical manifestation of
coronary artery disease . -
pubmed
The aim of our study was to assess the atherosclerotic burden in
patients with the first symptoms of
coronary artery disease (
CAD ) . -
pubmed
The study population consisted of 100 consecutive
patients ( new - onset severe
angina or
myocardial infarction ) and 70 age- and sex - matched volunteers without symptoms of
CAD . -
pubmed
Functional and morphologic atherosclerotic markers were sought in carotid , brachial , and femoral arteries of all subjects by means of high - resolution ultrasonography while coronary arteriography was performed in the
CAD patients only . -
pubmed
A total of 347
coronary lesions , 230 ( 66 % ) of them obstructive , were discovered in the
CAD patients as well as 105
peripheral plaques , of which 26 ( 25 % ) were obstructive . -
pubmed
Endothelium - dependent vasodilation , as assessed by the brachial flow - mediated response ( FMR ) , was reduced by 50 % in the
CAD patients ( P< ; 0.001 vs controls ) ; it was also observed in carotid and femoral arteries by the cold pressor test . -
pubmed
Furthermore , endothelium - independent vasodilation was significantly impaired in all investigated peripheral arteries of the
CAD patients ( P< ; 0.05 - 0.001 vs controls ) . -
pubmed
Intima - media thickness ( IMT ) was increased in the carotid arteries of the
CAD patients by 43 % , in brachial arteries by 20 % , and in femoral arteries by 57 % ( P< ; 0.01 - 0.001 vs controls ) . -
pubmed
Peripheral atherosclerosis was more developed in older
patients but was similar in patients with different clinical presentation . -
pubmed
In conclusion , the
atherosclerotic process was quite advanced in coronary as well as peripheral arteries of our
patients with the first clinical presentation of
CAD . -
pubmed
PURPOSE : In this prospective study we evaluate the effect of combined transurethral resection of early
muscle invasive bladder cancer and immunotherapy with bacillus Calmette - Guerin ( BCG ) in
patients unfit for radical cystectomy or refusing more aggressive therapies . -
pubmed
Inclusion criteria were histologically proven
muscle invasive transitional cell carcinoma of the bladder with a
tumor - free second resection and negative staging examinations in
patients unfit for radical cystectomy or refusing more aggressive therapies . -
pubmed
One
patient died of progressive
recurrence in the upper urinary tract . -
pubmed
CONCLUSIONS : The data show encouraging results for transurethral resection of
bladder tumor with intravesical BCG therapy in select
patients with T2a
bladder cancer who are not candidates for radical cystectomy . -
pubmed
The purpose of this chapter is to discuss the wealth of
animal studies of stress - induced modulation of immunity , and to relate our understanding of stress and immunity to clinical populations , particularly
cancer patients . -
pubmed
More effective therapy is , therefore , needed for
patients with
metastatic RCC . -
pubmed
CONCLUSION : These findings indicate that
IAB-1 may have an antitumor activity against
human RCC by inducing apoptosis , suggesting its potential clinical application for gene therapy against
RCC . -
pubmed
HYPOTHESIS :
Aminophylline is a central respiratory stimulant and will decrease the incidence of
PGE1 - associated
apnea and the need for intubation for
apnea in
infants with ductal - dependent
congenital heart disease . -
pubmed
In a prospective , double - blinded , placebo - controlled study , newborn
infants with ductal - dependent
congenital heart disease were randomized to receive either
aminophylline or placebo during initiation and maintenance of
PGE1 , which was started at 0.01 microg / kg / min and increased to 0.03 microg / kg / min . -
pubmed
Infants receiving
aminophylline ( n = 21 ) were less likely to have
apnea ( 2 vs 11 ) or be intubated for
apnea ( 0 vs 6 ) . -
pubmed
CONCLUSIONS :
Aminophylline was effective for the prevention of
apnea and intubation for
apnea associated with
PGE1 in
infants with ductal - dependent
congenital heart disease . -
pubmed
Cutaneous candidiasis in a
dog . -
pubmed
This blinded , randomized , controlled trial of 112
patients studied time to graft
thrombosis and graft loss , comparing monthly Qa plus standard surveillance ( dynamic venous pressure and physical examination ) ( treatment group ) to standard surveillance alone ( control group ) . -
pubmed
The rate of graft
thrombosis per
patient - year at risk was 0.41 and 0.51 in the control and treatment groups , respectively . -
pubmed
Second , using distinct bioinformatic tools , we set out to identify transcription factors that could be involved in the transcriptional regulation of genes known to be associated with
aggressive behavior in
mice . -
pubmed
According to the data obtained in this work , the
strains belong to a novel species , for which the name
Paenibacillus favisporus sp . - pubmed
METHODS : The data was collected prospectively for all
patients with
STEMI who received thrombolysis in the emergency department over a one - year period from January 2001 to December 2001 . -
pubmed
CONCLUSION : Emergency physicians can administer thrombolytic treatment appropriately , quickly and safely in
patients with
STEMI . -
pubmed
OBJECTIVE : To describe and analyse the clinical characteristics of 100
patients with
antiphospholipid syndrome (
APS ) associated with
infections . -
pubmed
The main associated
infections and agents included
skin infection ( 18 % ) ,
HIV ( 17 % ) ,
pneumonia ( 14 % ) ,
hepatitis C ( 13 % ) , and
urinary tract infection ( 10 % ) . -
pubmed
Twenty three
patients died following
infections and
thrombotic episodes ( 16 with catastrophic
APS ) . -
pubmed
CONCLUSIONS : Various different
infections can be associated with
thrombotic events in
patients with
APS , including the potentially lethal subset termed catastrophic
APS . -
pubmed
Gram - negative bacteria of the
Burkholderia cepacia complex (
Bcc ) are opportunistic pathogens that can infect the lungs of
cystic fibrosis (
CF ) patients and can be transmitted among these patients , causing epidemics in the
CF community . -
pubmed
Although expansion of TNRs is associated with several
human genetic diseases , the expansion mechanism is poorly understood . -
pubmed
Carotenemia associated with
green bean ingestion . -
pubmed
Excessive and prolonged ingestion of
carotene - rich , yellow- or orange - colored foods such as
carrots and
winter squash is the most common cause , but more rarely it may be associated with consumption of other foods as well as with
hypothyroidism ,
diabetes mellitus ,
anorexia nervosa ,
liver disease , or
kidney disease . -
pubmed
Herein we describe
carotenemia in an 8 - month - old Caucasian girl secondary to increased consumption of commercial infant food
green beans . -
pubmed
Severe acute respiratory syndrome (
SARS ) , a life - threatening disease , is caused by the newly identified virus
SARS coronavirus (
SARS - CoV ) . -
pubmed
DP - class
prostaglandins and
prostaglandin analogs ( collectively ,
prostaglandins or
PGs ) such as
PGD2 ,
BW245C ,
ZK110841 , and
ZK118182 , lower intraocular pressure ( IOP ) in
animal models of
ocular hypertension . -
pubmed
A new analog of
ZK118182 (
AL-6556 ;
13,14 - dihydro - ZK118182 ) was synthesized , and the
isopropyl ester of
AL-6556 (
AL-6598 ) was shown recently to lower IOP in the ocular
hypertensive cynomolgus monkey model of
glaucoma and in
human subjects . -
pubmed
In 2002 , there were an estimated 13,400 emergency department visits nationwide for
horse - related
injuries among children younger than 15 years . -
pubmed
Most serious
injuries occur when a rider is thrown from a
horse , which is often accompanied by being dragged or crushed by the
horse . -
pubmed
However , hoof
kick injuries to an unmounted child represent about 30 % of
horse - related
injuries and may result in more severe
injury . -
pubmed
The effectiveness of helmets in preventing serious
head injury in
horse - related accidents has been very well established . -
pubmed
Recommendations for the prevention of
horse - related
injury include requiring helmet use on and near a
horse , use of safety stirrups to prevent
drag injury , matching rider skill with the appropriate
horse , and providing close adult supervision . -
pubmed
A Turkish
woman aged 44 years who presented with a 1 month history of
abdominal pain ,
fatigue and
weight loss of 10 kg was diagnosed as having acute
tubulointerstitial nephritis . -
pubmed
It is important to be aware of
tubulointerstitial nephritis and
uveitis syndrome in order to achieve a quick diagnosis in
patients with
renal impairment and
tubular dysfunction with minor symptoms so that appropriate management can be started early . -
pubmed
Three
patients had MMG - positive
BM , four
patients had MMG - negative BM before allografting , and two were undetermined . -
pubmed
Children hospitalized with
skin and soft tissue infections : a guide to antibacterial selection and treatment . -
pubmed
The main pathogens involved in these
infections are
Staphylococcus aureus and group A beta - hemolytic streptococci , but enteric organisms also play a role especially in
nosocomial infections . -
pubmed
A plasmid identified in a
Bifidobacterium catenulatum strain ( pBC1 ) was chosen for further characterization based on its small size and stability . -
pubmed
Hyperlipidemic mice present enhanced catabolism and higher mitochondrial
ATP - sensitive K+ channel activity . -
pubmed
We have recently shown that
hypertriglyceridemic (
HTG )
mice present higher mitochondrial resting respiration unrelated to UCPs . -
pubmed
In agreement with higher metabolic rates , food ingestion was significantly larger in HTG
mice , without enhanced
weight gain . -
pubmed
CONCLUSIONS : These results show that primary
hyperlipidemia leads to an elevation in liver mitoK(
ATP ) activity , which may represent a regulated adaptation to oxidize excess
fatty acids in
HTG mice . -
pubmed
Minocycline delays but does not attenuate the course of experimental
autoimmune encephalomyelitis in
Streptococcus pneumoniae - infected
mice . -
pubmed
OBJECTIVES : Experimental
autoimmune encephalomyelitis (
EAE ) , the
animal model of
multiple sclerosis (
MS ) , can be aggravated by a mild
Streptococcus pneumoniae infection . -
pubmed
This study was performed to assess whether treatment with antibiotics inhibiting
bacterial protein synthesis reduces the detrimental effect of
infection on the course of
EAE . -
pubmed
Seven days after induction of
EAE ( prior to the onset of symptoms )
mice were infected intraperitoneally with
S. - pubmed
Mice treated with
minocycline developed symptoms of
EAE 1 day later than
mice treated with
ceftriaxone . -
pubmed
These data do not support the hypothesis of superiority of a
bacterial protein synthesis inhibitor over a
beta - lactam antibiotic for the treatment of concomitant
infections during the latent phase of
EAE or
MS . -
pubmed
METHODS : An interventional study of 39
females with
MVP syndrome with treadmill exercise endurance training for 12 weeks . -
pubmed
Postural orthostatic tachycardia syndrome : anesthetic implications in the obstetric
patient . -
pubmed
Most of the
tumors detected in
Japanese quail were
lymphosarcomas , and 81 % of these
neoplasias contained CD3 + cells by immunoperoxidase . -
pubmed
REV APC-566 was also oncogenic in
chickens and
turkeys infected at 1 day of age , with
tumors appearing as early as 58 days after
infection in
chickens and at 13 wk of age in
turkeys . -
pubmed
Effects of
isoflurane and
sevoflurane anesthesia on arteriovenous shunt flow in the lower limb of
diabetic patients without
autonomic neuropathy . -
pubmed
The aim of this study was to test the hypothesis that the function of arteriovenous anastomoses was disordered in mild
diabetic patients without apparent
neuropathy , and that volatile anesthetics opened arteriovenous shunts more greatly in nondiabetic
patients than
diabetic patients . -
pubmed
Arterial - venous
oxygen content difference ( A - VDeltaO2 ) and partial
oxygen pressure index ( Pvo2 / Pao2 , the ratio of
oxygen tension in femoral vein blood to that in femoral artery blood ) were measured before and during
isoflurane or
sevoflurane anesthesia in 16
diabetic and 22 nondiabetic
patients . -
pubmed
Skin temperatures of the foot and leg were measured in 14
diabetic and 15 nondiabetic
patients using thermography before and during anesthesia . -
pubmed
RESULTS : Pvo2 / Pao2 before anesthesia was significantly higher in
diabetic patients . -
pubmed
Foot temperatures were higher in
diabetics before anesthesia , and increased gradually and significantly in both groups during anesthesia , but with a greater increase in nondiabetic
patients . -
pubmed
CONCLUSIONS : Diabetic
patients have a higher Pvo2 / Pao2 and a small core - to - peripheral temperature gradient before anesthesia , suggesting latent dysfunction of the autonomic nerve system , even in the absence of
autonomic neuropathy . -
pubmed
Volatile anesthesia opens the arteriovenous shunt in nondiabetics to a greater extent than in
diabetic patients . -
pubmed
Echocardiography was performed on day 1 prior to
AMI and on day 14 just before the
rats were to be sacrificed for cellular and molecular studies . -
pubmed
Additionally , day 14 left ventricular ( LV ) ejection fraction was significantly lower in nontreated
AMI rats than in healthy control and
losartan - treated
AMI rats ( all values of P & lt ; 0.0001 ) . -
pubmed
Topics covered in invited lectures included detection of novel respiratory viral pathogens and viral evolution , characterization of the 1918 pandemic virus , human
metapneumovirus infections ,
human respiratory epithelial cultures for studying viral pathogenesis , the role of respiratory viruses in the pathogenesis of
asthma ,
influenza - bacterial interactions , advances in generating vaccine candidates against global respiratory threats like
avian influenza and
SARS , antiviral resistance surveillance in
influenza viruses , and a mini - symposium on advances in viral diagnostics . -
pubmed
Other talks covered the live , attenuated intranasal
influenza vaccine , monoclonals for
respiratory syncytial virus (
RSV ) , mechanisms of antiviral resistance in
influenza B , and novel inhibitors for
influenza ,
RSV and
rhinovirus infections . -
pubmed
Toe - out gait in
patients with
knee osteoarthritis partially transforms external knee adduction moment into flexion moment during early stance phase of gait : a tri - planar kinetic mechanism . -
pubmed
Altered gait kinematics and kinetics are observed in
patients with
medial compartment knee osteoarthritis . -
pubmed
To test this hypothesis , gait data from 180
subjects diagnosed with
medial compartment knee osteoarthritis were examined using two frames of reference . -
pubmed
These results indicate that toe - out gait in
patients with
medial compartment knee osteoarthritis transforms a portion of the adduction moment into flexion moment in early stance phase , suggesting that load is partially shifted away from the medial compartment to other structures . -
pubmed
PURPOSE OF REVIEW : The aim of this article is to review the recently published studies addressing various treatment approaches for
asthma in preschool
children . -
pubmed
Once
children at highest risk for persistence of
wheezing are identified , various management strategies may be thoroughly studied . -
pubmed
In addition to examining clinical efficacy , studies investigating the effects of these treatment modalities on the underlying
airway inflammation have recently increased in number and quality and confirm the anti - inflammatory actions of these therapeutic strategies in the preschool
child with
asthma . -
pubmed
SUMMARY : Evidence for the preferred treatment strategies for persistent
asthma in young
children remains incomplete . -
pubmed
RESULTS : A total of 1,041
patients ( age : 11.8 + /- 4.2 years ;
diabetes duration : 6.0 + /- 3.6 years ; average CSII duration : 2.0 + /- 1.3 years ; HbA(1c ): 8.0 + /- 1.3 % [ means + /- SD ] ) participated . -
pubmed
( type
strain MSL-09(T ) = KCTC 19272(T ) = DSM 19266(T ) ) ,
Nocardioides bigeumensis sp . - pubmed
( type
strain MSL-19(T ) = KCTC 19290(T ) = DSM 19320(T ) ) and
Nocardioides agariphilus sp . - pubmed
ARES is a multicenter , prospective study of the prevalence , management , and repercussions on the quality of life of
anemia in renal transplant
patients with a
reduced renal function (
creatinine clearance according to Cockcroft - Gault : & lt;/=60 and & gt;15 mL / min ) . -
pubmed
Treatment with oral or intravenous
iron was much more frequent in
anemic patients ( 31.6 % vs 9.9 % ; P & lt ; .001 ) . -
pubmed
In conclusion ,
iron deficiency in renal transplant
patients with
chronic nephropathy is frequent and insufficiently treated . -
pubmed
Although it may be an aggravating factor , it was not shown to be a determining factor for the presence or absence of
anemia in the
patients as a group . -
pubmed
In this paper we expand these observations to demonstrate that these
mice develop all the clinical and immunological features of primary
Sjogren ' s disease in the same relative time frame as
patients with primary
Sjogren ' s disease : stage 1 - early
hypergammaglobulinemia and autoantibody production , stage 2 - decreased salivary gland function with early lymphocytic infiltration of the submandibular glands only , but antibody deposition in the submandibular and parotid glands , stage 3 - lymphocytic infiltration of the submandibular , parotid and lacrimal glands with B and T lymphocytes and plasma cells along with
interstitial lung disease and
mild renal disease , and stage 4 - large
B cell lymphoma . -
pubmed
We explore whether patterns of covariation between fitness and ageing across 25 cytoplasmic lines , sampled from a population of
Drosophila melanogaster , are consistent with the genetic associations predicted under MA or
AP . -
pubmed
[ The diurnal variability of blood pressure in
patients with
hypertension and
rheumatoid arthritis ] . -
pubmed
BACKGROUND : The
patients with
rheumatoid arthritis have high prevalence of
hypertension and increased risk of cardiovascular morbidity and mortality . -
pubmed
OBJECTIVE : To determine the level of clinical blood pressure ( BP ) and 24h ambulatory BP in
patients with
rheumatoid arthritis and
hypertension . -
pubmed
GROUP OF
PATIENTS : 60
patients with clinically stable
rheumatoid arthritis and treated or newly diagnosed
hypertension . -
pubmed
CONCLUSION :
Patients with
rheumatoid arthritis and
hypertension have a slightly increased pulse pressure ( 55 mm Hg for clinical BP and 50 mm Hg for 24h ambulatory BP ) in comparison to arbitrary limits in generally population . -
pubmed
Patients treated with
prednison and
nonsteroidal anti - inflammatory drugs were more often nondippers ( 34 % ) in
systolic BP than
hypertensive control . -
pubmed
The
patients treated with
methotrexate ( 47 % ) ,
prednisone ( 37 % ) and
nonsteroidal anti - inflammatory drugs ( 38 % ) were more often excessive dippers in
diastolic BP than
hypertensive control . -
pubmed
Fusarium wilt (
FW ) is one of the most economically damaging
cotton diseases worldwide , causing yellowing ,
wilting ,
defoliation ,
vascular tissue damage and ultimately
death . -
pubmed
The secondary objective of this study was to determine whether
individuals at increased risk for developing
voice problems ( i.e. -
pubmed
Furthermore , the extended test was applied to 126
patients with
olfactory loss and 71 normosmic individuals . -
pubmed
infusion at doses between 1 and 16 mg / kg , with repeated dosing every 1 to 3 weeks ( based on
patient - individualized PK assessment ) until
disease progression . -
pubmed
A phase II study is ongoing to evaluate the clinical activity of
AS1402 in
patients with advanced
breast cancer . -
pubmed
The effects of
ciprofloxacin and
ursodeoxycholic acid on
bacterial translocation in
obstructive jaundice . -
pubmed
BACKGROUND / AIMS : We aimed to search the effects of two different drugs in
bacterial translocation , both in combination and alone :
ursodeoxycholic acid , the effectiveness of which was evidenced previously , and
ciprofloxacin , which had not been used before , in an experimental
obstructive jaundiced rat model . -
pubmed
CONCLUSIONS :
Ciprofloxacin and
ursodeoxycholic acid have a synergic effect on prevention of
bacterial translocation in
obstructive jaundice . -
pubmed
A study has been made of the pH stability of centrifugally purified
strains of
influenza virus with respect to the biological properties of
mouse infectivity and
chicken red blood cell agglutinating activity . -
pubmed
in
phosphate buffer , the infectivity of
PR8 virus was found to be most stable at pH 6.5 - 7 ; the
swine virus , at pH 7 - 7.9 ; and the Lee
strain , at a pH of 7.9 or higher . -
pubmed
Furthermore , the
Lee virus was much less stable in dilute solution in
phosphate buffer , even under optimum conditions of pH , than either the PR8 or
swine strains . -
pubmed
The different
strains of
influenza virus were found to possess certain characteristics in common . -
pubmed
In detailed experiments with the
Lee virus , it was found that the infectivity and CCA activity of this
strain at pH 7 and at a protein concentration of 0.1 mg . -
pubmed
Dopaminergic interneurons synapse onto cells that route signals to
mammalian retinal
ganglion cells , but it is unknown whether
dopamine can activate receptors in these
ganglion cells and , if it does , how this affects their excitability . -
pubmed
Then , 11
patients who had been clinically diagnosed with
Meniere ' s disease and a
patient with
sudden hearing loss were scanned . -
pubmed
A newly - optimized protocol allowed the smooth , three - dimensional visualization of
endolymphatic hydrops in all
patients with
Meniere ' s disease . -
pubmed
CONCLUSION : Volumetrically separate visualization of endo-/perilymphatic space is now feasible in
patients with
Meniere ' s disease using an optimized 3D - real IR sequence , a 32 - channel head coil , at 3 T , after intratympanic administration of
Gd - DTPA . -
pubmed
Subtle genetic alterations in PSD proteins may induce neural network dysfunctions that may have some phenotypic relevance in
human psychiatric disorders , as suggested in several recent studies . -
pubmed
An anatomical study was carried out using six
feline cadavers to determine anatomic landmarks . -
pubmed
An ultrasonographic ' in vitro ' study was performed using eight pelvic limbs from four fresh
feline cadavers to assess the ScN in three regions ( glutea , femoralis and popliteal ) using a 4 - 13MHz linear transducer . -
pubmed
against
paracetamol - induced
hepatic injury in
rats . -
pubmed
OBJECTIVE :
Methanol extract of whole plant of
Amaranthus caudatus ( MEAC ) was screened for hepatoprotective potency against
paracetamol (
PCM)-induced
liver damage in
Wistar rats . -
pubmed
CONCLUSION :
MEAC shows significant hepatoprotective activity against
PCM - induced
liver damage in
rats . -
pubmed
This finding supports the use of the
plant in ethnomedicine for the treatment of
liver diseases . -
pubmed
OBJECTIVE : To determine the interrelationships between MRI - defined lesion and
atrophy measures of spinal cord involvement and brain involvement and their relationships to disability in a small cohort of
patients with
multiple sclerosis (
MS ) . -
pubmed
DESIGN AND METHODS : 3 T MRI of the whole brain and whole spinal cord was obtained in 21
patients with
MS , including 18 with relapsing - remitting , one with secondary progressive , one with primary progressive , and one with a clinically isolated
syndrome . -
pubmed
CONCLUSIONS AND RELEVANCE : In this preliminary study of mildly disabled , treated
MS patients , cervical
spinal cord atrophy most strongly correlates with
physical disability in
MS when accounting for a wide range of other CNS measures of lesions and
atrophy , including thoracic or whole spinal cord volume , and cerebral gray , white or whole brain volume . -
pubmed
The weak relationship between spinal cord and
brain lesions and
atrophy may suggest that they progress rather independently in
patients with
MS . -
pubmed
METHODS : Thirty - seven consecutive
patients with
adolescent idiopathic scoliosis were included in this study from June 2001 to August 2003 . -
pubmed
heterophylla seeds
ethanol extract ( VSE ) on
mice model of
immunological hepatitis and
acute inflammation ] . -
pubmed
heterophylla seeds
ethanol extract(VSE ) on immunological
hepatitis and
acute inflammation mice model . -
pubmed
Meanwhile , VSE could ameliorate the
ear swelling induced by croton oil and reduced the thickness of
mice hind paw induced by carrageenan as well . -
pubmed
BACKGROUND : The incidence of
children 's
forearm fractures is increasing worldwide . -
pubmed
MATERIALS AND METHODS : All 168
children ( & lt;16 years ) admitted to our paediatric
trauma centre due to diaphyseal both - bone forearm
fractures during 2000 - 2009 were included . -
pubmed
Studies of
allopurinol and
febuxostat lowering of serum
urate have once again raised the tantalizing possibility that
hyperuricemia is harmful to the kidneys by showing better preservation of
glomerular filtration rate (
GFR ) in treated
patients . -
pubmed
Running time to
fatigue was significantly greater in HPdTSP
mice than in TS
mice . -
pubmed
[ A retrospective study of
UFT and oral
leucovorin plus
PSK combination adjuvant chemotherapy in
patients with stage III
colon cancer ] . -
pubmed
SUBJECTS : Between 2003 and 2009 , 273 stage III
colon cancer patients underwent surgery in our institute , and we studied 156 of them . -
pubmed
Using 20 ng / mL as a cut - point value , 205
PCa patients , who underwent RP , were stratified into two groups . -
pubmed
Patients , who might benefit the most from RP , are those with organ confined
PCa and negative lymph nodes . -
pubmed
RESULTS : Data from 158 relevant studies was used to characterise the epidemiology of the 10 most extensively reported maternal
infections with the following median prevalence rates :
Treponema pallidum ( 2.6 % ) ,
Neisseria gonorrhoeae ( 1.5 % ) ,
Chlamydia trachomatis ( 5.8 % ) , Group B
Streptococcus ( 8.6 % ) ,
bacterial vaginosis ( 20.9 % ) ,
hepatitis B virus ( 4.3 % ) ,
hepatitis C virus ( 1.4 % ) ,
Cytomegalovirus ( 95.7 % past
infection ) ,
Rubella ( 8.9 % susceptible ) and
Herpes simplex ( 20.7 % ) . -
pubmed
RESULTS : Out of the 209
patients , 43 ( 21 % ) were diagnosed with
impingement syndrome or soft - tissue pathology . -
pubmed
DBM administered in a sustained manner showed similar bone quality and strength to
osteoporotic control
animals . -
pubmed
MATERIALS AND METHODS : Twenty - five
patients ( M : F = 13:12 , mean age : 52.1 + -15.2 years ) with pathologically proven
glioblastoma who underwent DSC MR imaging before surgery were included . -
pubmed
Thus , we believe that DSC - enhanced perfusion MR imaging could be helpful in predicting genetic alterations that are crucial in predicting the prognosis of and selecting tailored treatment for
glioblastoma patients . -
pubmed
Orally active opioid mu / delta dual agonist
MGM-16 , a derivative of the
indole alkaloid mitragynine , exhibits potent antiallodynic effect on
neuropathic pain in
mice . -
pubmed
Systemic administration of
MGM-16 produced antinociceptive effects in a
mouse acute
pain model and antiallodynic effects in a chronic
pain model . -
pubmed
Postoperative
pancreatic fistula developed in nine of 45
patients in the IRPJ group and 10 of 45
patients in the PG group ( P = 0.796 ) . -
pubmed
Steatorrhea at 1 year was reported in nine of 42 IRPJ
patients and 18 of 41 PG
patients ( P = 0.029 ) . -
pubmed
Evaluation of
fracture risk and potential drug holidays for postmenopausal
women on long - term
bisphosphonate therapy . -
pubmed
STUDY OBJECTIVE : To describe characteristics of postmenopausal
women on long - term
bisphosphonate therapy who fall into one of four
fracture risk categories ( low , mild , moderate , high ) , and to determine the prevalence of women eligible for a drug holiday . -
pubmed
PATIENTS : A total of 201 postmenopausal
women of ages 55 - 89 years , with
osteopenia or
osteoporosis , prescribed
bisphosphonate therapy for & gt;4 years , between October 10 , 2002 and September 9 , 2012 . -
pubmed
Cytotoxicity of
benzophenanthridine alkaloids from the roots of
Zanthoxylum nitidum (
Roxb . ) - pubmed
Compounds 7 and 11 also showed strong
cytotoxicity when tested against the four
human cancer cell lines (
A549 ,
Hela ,
SMMC-7721 and
EJ ) , while only compounds 12 and 13 displayed
cytotoxicity in inhibiting
BALL-1 proliferation among all the compounds . -
pubmed
METHOD : Subjects were 928 Caucasian
patients who presented to an out - patient clinic specializing in the assessment and treatment of
anxiety and
mood disorders . -
pubmed
This interest , however , is tempered by a number of unresolved issues , including the safety of using such drugs in advanced
CKD and
ESRD populations , and the potential for differences in drug efficacy according to race and ethnicity of
patient populations . -
pubmed
Molecular characteristics of bap - positive
Staphylococcus aureus strains from
dairy cow mastitis . -
pubmed
Major cardiovascular and cerebrovascular adverse events occurred in 1
patient , with no inhospital
deaths observed . -
pubmed
Vagus nerve stimulation ( VNS ) is generally considered as a palliative treatment for
patients with drug - resistant partial - onset
epilepsy . -
pubmed
Screening of Probiotic Candidates in
Human Oral Bacteria for the Prevention of
Dental Disease . -
pubmed
We screened 14 lactobacillus
strains and 36
streptococcus strains out of 896 oral isolates derived from healthy subjects . -
pubmed
As a result ,
Lactobacillus crispatus YIT 12319 ,
Lactobacillus fermentum YIT 12320 ,
Lactobacillus gasseri YIT 12321 , and
Streptococcus mitis YIT 12322 were selected because they showed no cariogenic potential in an artificial mouth system and a lower risk of experimental
infective endocarditis in a
rat model . -
pubmed
Clinical and pathological complete remission in a
patient with
metastatic renal cell carcinoma (
mRCC ) treated with
sunitinib : Is
mRCC curable with targeted therapy ? -
pubmed
We report a
patient with
metastatic clear - cell renal cell carcinoma (
mRCC ) who presented with primary
tumor in situ in the left kidney and
metastases to bone , liver , lungs , and brain . -
pubmed
STUDY DESIGN : Over a 1.5 - year period at a Chinese tertiary obstetric centre ,
women at risk of Hb
Bart ' s disease were given the option of a non - invasive approach to exclude an affected pregnancy between 11 weeks and 13 weeks and 6 days of gestation , with a routine rescan after a 2 - week interval . -
pubmed
Case 1 : A 35 - year - old
woman who underwent right single LTx and sustained uncontrollable massive chylous
ascites . -
pubmed
Case 2 : A 50 - year - old
woman who underwent left single LTx had
pneumothorax of the native lung 16 months after the LTx . -
pubmed
Case 3 : A 33 - year - old
woman , who underwent left single LTx , had
recurrence of
LAM in the transplanted lung 2 years after the LTx . -
pubmed
Case 4 : A 47 - year - old
woman , who underwent right single LTx , developed repeated high
fevers . -
pubmed
[ Establishment of
chondrocyte degeneration model in vitro by
rat serum ] . -
pubmed
CONCLUSION : The results indicate that
rat serum can induce chondrocyte degeneration and may be used for
osteoarthritis model in vitro . -
pubmed
METHODS AND MATERIALS :
Patients ( n = 21 ) treated with IGABT for
carcinoma cervix under the IntErnational study on MRI - guided BRachytherapy in locally Advanced
CErvical cancer protocol were analyzed . -
pubmed
Bovine leukemia virus (
BLV ) is a deltaretrovirus which infects and induces proliferation of B - lymphocytes in the peripheral blood circulation and in lymphoid organs primarily of
cattle , leading to
leukemia /
lymphoma . -
pubmed
3
patients had severe
bleeding ( 12.5 % , 3/24 ) in bridging group ; compared with the other 2 groups , there were significant difference ( chi(2)=9.161 , P=0.010 ) . -
pubmed
Antipsychotics are the drugs used in the treatment of
SCZ but it remains controversial the impact that typical vs. atypical antipsychotics has on the oxidative stress status in
SCZ patients . -
pubmed
Rice sheath blight disease , caused by the fungus
Rhizoctonia solani , is considered the second most important disease of
rice after blast . -
pubmed
OBJECTIVE : To evaluate the diagnostic value of cytological greater omental milky
spot examination for the diagnosis of peritoneal
metastasis in
gastric cancer patients . -
pubmed
METHODS : A total of 136
patients diagnosed with
gastric cancer and without distant
metastasis were enrolled in our study . -
pubmed
All
patients underwent laparoscopy and CH40 suspension liquid dye of peritoneal lymph nodes preoperatively as well as
ascites or peritoneal lavage fluid collections and excisions of marked greater omental milky
spot tissues perioperatively . -
pubmed
The GAlert SCs are deficient in self - renewal and subjected to accelerated depletion during regeneration and aging and fail to repair
muscle injury in old
mice . -
pubmed
Increased FC was more common in
patients with
pancreatic insufficiency . -
pubmed
Whether increased FC reflects intestinal
inflammation in
patients with
CF remains to be determined . -
pubmed
Fertility sparing approach as the standard of care in young
patients with immature
teratomas . -
pubmed
[ Preoperative MRI diagnostics of the topographic features of neck arteries in the
patients presenting with
chronic tonsillitis ] . -
pubmed
A total of 109
patients presenting with chronic
tonsillitis ( including 64
women and 45 men at the age varying from 15 to 54 years ) were available for the examination . -
pubmed
Abnormalities in the internal carotid artery were documented in 11.9 % of the cases ( including C- and S - shaped tortuosity of internal carotid artery in 6.88 % , kinking and coiling of internal carotid artery in 4.13 % and 0.92 % of the
patients , respectively ) . -
pubmed
The results of the present study should be taken into consideration when prescribing the surgical treatment to the
patients suffering not only from
chronic tonsillitis but also from other
ENT diseases , in the first place pharyngotympanic tube pathology . -
pubmed
RESULTS : A 41 - year - old
man with a history of
aniridic keratopathy and
limbal stem cell deficiency underwent KLAL in his right eye . -
pubmed
CONCLUSIONS : We present the first case of
CMV disease in a seronegative
patient who received a presumed
CMV - seropositive donor KLAL . -
pubmed
PURPOSE : To determine if preoperative Goldmann Visual Field ( GVF ) testing in
patients with functional
dermatochalasis accurately depicts the postoperative superior visual field ( SVF ) outcome . -
pubmed
METHODS : A prospective cohort study was done to compare preoperative and postoperative GVF field tests in
patients undergoing upper eyelid blepharoplasty for treatment of
dermatochalasis . -
pubmed
RESULTS : Forty - six eyelids ( 23
patients ) who underwent blepharoplasty for
dermatochalasis were included . -
pubmed
BACKGROUND : Transcatheter aortic valve implantation ( TAVI ) is an effective treatment for severe
aortic stenosis in high - risk
patients . -
pubmed
OBJECTIVES : To assess the feasibility of recruitment and retention and to explore non - efficacy - based barriers to a blinded antipsychotic medication withdrawal programme for
adults with
LDs without
psychosis compared with treatment as usual . -
pubmed
PARTICIPANTS :
Adults with
LDs who are prescribed
risperidone for treatment of challenging behaviour with no known current
psychosis or previous
recurrence of
psychosis following prior drug reduction . -
pubmed
The purpose of this review is to summarize recent advances that have allowed us to better recognize , categorize , and treat
patients with
DED . -
pubmed
Patients with
NASH show many features of the
metabolic syndrome and , as a result , are at higher risk for postoperative cardiovascular morbidity and mortality . -
pubmed
Despite this ,
patients with
NASH have long - term graft and
patient survival rates comparable with other causes of
chronic liver disease . -
pubmed
There are two large prospective randomized trials establishing the safety and efficacy of breast IORT in early stage
breast cancer patients with sufficient follow - up time on thousands of
women . -
pubmed
The advantages of IORT for partial breast irradiation include : direct visualization of the target tissue ensuring treatment of the high - risk tissue and eliminating the risk of marginal miss ; the use of a single dose coordinated with the necessary surgical excision thereby reducing omission of radiation and the selection of mastectomy for
women without access to a radiotherapy facility or unable to undergo several weeks of daily radiation ; favorable toxicity profiles ;
patient convenience and cost savings ; radiobiological and
tumor microenvironment conditions which lead to enhanced
tumor control . -
pubmed
It may also be very useful in specific situations , such as prior to oncoplastic reconstruction to improve accuracy of adjuvant radiation delivery , or when used as a boost in higher risk
patients to improve
tumor control . -
pubmed
Non - pharmacological options for managing chronic
musculoskeletal pain in
children with pediatric
rheumatic disease : a systematic review . -
pubmed
Because
CMP is not always alleviated solely by the use of pharmacological approaches , the aim was to systematically review the available evidence regarding non - pharmacological treatment options for reducing
CMP in
patients with
PRD . -
pubmed
Materials and Methods : In this study , infants and
children who were referred for the evaluation of unilateral
hydronephrosis were enrolled . -
pubmed
Hemorrhagic bulla formation and the need for surgical intervention only presented for
D. - pubmed
As to laboratory features , lower platelet counts ( 20.0 x 103 / muL [ interquartile range , 14 - 66 x 103 / muL ] vs. 149.0 x 103 / muL [ 102.3 - 274.3 x 103 / muL ] , P = 0.001 ) , lower D - dimer level ( 1423.4 mug / L [ 713.4 - 4212.3 mug / L ] vs. 12,500.0 mug / L [ 2351.4 - 200,000 mug / L ] , P = 0.008 ) , higher proportion of
patients with moderate - to - severe
thrombocytopenia ( platelet count & lt ; 100 x 103 / muL ) ( 80 % vs. 16.7 % , odds ratio ( OR ) = 20.0 , 95 % CI , 2.77 - 144.31 ; P = 0.002 ) , and lower proportion of
patients with extremely high D - dimer ( & gt ; 5000 ng / mL ) ( 16.7 % vs. 66.7 % , adjusted OR = 0.1 ( 95 % CI , 0.01 - 0.69 ; P = 0.036 ) were found among cases of
D. - pubmed
acutus
envenomation compared to
D. - pubmed
The combination of
hemorrhagic bulla ,
thrombocytopenia , and a lack of extremely high D - dimer had good discriminatory power ( area under the curve ( AUC ) = 0.965 ; 95 % CI , 0.904 - 1.00 ) for distinguishing
D. - pubmed
Conclusions : The presentation of moderate to severe
thrombocytopenia ( platelet count & lt ; 100 x 103 / muL ) and
hemorrhagic bulla formation may indicate
D. - pubmed
These findings may help diagnose and select the right antivenom in
patients with unknown
snakebites who present significant
coagulopathy . -
pubmed
This study was to validate reliability and clinical utility of a PET
tumor segmentation method using multi - level Otsu ( MO - PET ) in standard National Electrical Manufacturers Association ( NEMA ) image quality ( IQ ) phantom and
patients with
osteosarcoma . -
pubmed
Repeated measurements of MTV ( MO - PET ) of the primary
tumors showed excellent reproducibility with ICC of 0.994 ( 0.989 - 0.997 ) in
patients with
osteosarcoma . -
pubmed
This emerging approach is changing how physicians diagnose and treat
infectious disease , with applications spanning a wide range of areas , including antimicrobial resistance , the microbiome ,
human host gene expression ( transcriptomics ) and oncology . -
pubmed
Isolation of Phage Lysins That Effectively Kill
Pseudomonas aeruginosa in Mouse Models of
Lung and Skin Infection . -
pubmed
Evaluating the Impact of Different Hypercaloric Diets on Weight Gain ,
Insulin Resistance ,
Glucose Intolerance , and its Comorbidities in
Rats . -
pubmed
Animal experimentation has a long history in the study of
metabolic syndrome - related disorders . -
pubmed
Knowing that different diets can precipitate different
metabolic disease phenotypes , herein we characterized several hypercaloric
rat models of
obesity and
type 2 diabetes , comparing each with a genetic model , with the aim of identifying the most appropriate model of
metabolic disease . -
pubmed
All
animal models presented with
insulin resistance and
dyslipidemia except the HF+
STZ and HSu 4 weeks , which argues against the use of these models as
metabolic syndrome models . -
pubmed
We conclude that the latter model presents a phenotype most consistent with that observed in
humans with
metabolic disease , exhibiting the majority of the phenotypic features and comorbidities associated with
type 2 diabetes in
humans . -
pubmed
Aim : This study aimed to compare
smear layer removal ability of different solutions of
Triphala ( TA ) when used in specific irrigant protocols in curved canals . -
pubmed
Animal models of
Sjogren ' s syndrome : an update . -
pubmed
Animal models have served as useful tools for studying
SS pathogenesis with several advantages . -
pubmed
A number of
animal models recapitulating key characteristics of primary
SS patients including
secretory dysfunction ,
glandular inflammation and presence of autoantibodies were developed in the past years . -
pubmed
The studies based on the
animal models of
SS have provided significant insight in
SS pathogenesis and therapeutic intervention . -
pubmed
This review summarises current
animal models with primary
SS - like symptoms including spontaneous models , genetically modified models , induced models and humanised models , and discusses their contribution to the understanding of
SS aetiology and therapies . -
pubmed
Re : Comparison of outcomes between
hip fracture patients with concurrent
upper limb injuries and
patients with an isolated
hip fracture . -
pubmed
OBJECTIVES : The goal of this secondary analysis was to examine whether
N - acetylcysteine (
NAC ) reduced
depressive symptoms among
adults ( age 18 - 50 ) with
CUD ( N = 302 ) and whether the effect of
NAC on cannabis cessation varied as a result of baseline levels of
depression . -
pubmed
Adults with
CUD ( N = 302 ) were randomized to receive 2400 mg of
NAC daily or matched placebo for 12 weeks . -
pubmed
OBJECTIVES : To examine the effects of
corticosteroids on
death in
children and adults with
sepsis . -
pubmed
AUTHORS ' CONCLUSIONS : Moderate - certainty evidence indicates that
corticosteroids probably reduce 28 - day and hospital mortality among
patients with
sepsis . -
pubmed
Anisakis typica is one of the Anisakis species which potent to induce an
allergic reaction . -
pubmed
Role of Changes in Magnetic Resonance Imaging or Clinical Stage in Evaluation of Disease Progression for
Men with
Prostate Cancer on Active Surveillance . -
pubmed
It is hypothesized that
infarct stiffness alters regional mechanics and affects the likelihood of
human ventricular remodeling . -
pubmed
Identifying heat
shock response systems from the genomic assembly of
Ureibacillus thermophilus LM102 using protein - protein interaction networks . -
pubmed
Aim : In the present research , we evaluated the synergistic effects of
ketamine with two
azole derivatives ,
itraconazole and
fluconazole , on
strains of
Candida spp . -
pubmed
METHODS : From 2016 to 2018 , 13
patients ( eight with
scar contracture and five with a
depressed scar ) were treated using dermofat grafts from the groin . -
pubmed
The harvested dermofat was then inserted into the undermined dead space after the
contracture was released , and a bolster suture was done for fixation considering the
patient 's contour and asymmetry . -
pubmed
Survival estimation of
melanoma patients with brain
metastasis using the
Melanoma - molGPA score : external validation from a French cohort . -
pubmed
Metastatic melanoma patients are a heterogeneous subgroup with variable prognosis . -
pubmed
Melanoma molecular graded prognostic assessment (
Melanoma - molGPA ) is a new prognostic score for BM
melanoma patients . -
pubmed
As several prospective clinical trials are addressing the issue of optimal therapy including the impact of local treatment for these
patients , the
Melanoma - molGPA is a useful tool in BM
melanoma patients . -
pubmed
The larval form of tapeworms of the
Echinococcus granulosus sensu lato species cluster cause an important
zoonotic infection ,
cystic echinococcosis (
CE ) . -
pubmed
In this work , we characterized isolates from
human CE cases . -
pubmed
Our findings suggest that
pigs are important intermediate hosts for
human CE in Slovenia . -
pubmed
Purpose : Accumulating evidence has indicated that circRNAs are closely involved in
tumorigenesis and progression of
human cancers . -
pubmed
First - line chemotherapy in very elderly
patients with metastatic
pancreatic cancer :
Gemcitabine monotherapy vs combination chemotherapy . -
pubmed
Considering the severe
toxicities of combination chemotherapy ,
gemcitabine monotherapy ( G mono ) could be used as a first - line treatment in very elderly
patients or those with a low Eastern Cooperative Oncology Group status . -
pubmed
METHODS : We retrospectively analyzed 104 older
patients with
pancreatic cancer who underwent chemotherapy with G mono ( n = 45 ) or combination therapy ( n = 59 ) as a first - line treatment between 2011 and 2019 . -
pubmed
All
patients were histologically diagnosed with
ductal adenocarcinoma . -
pubmed
However , G mono is superior for the management of metastatic
pancreatic cancer in very elderly
patients . -
pubmed
METHODS : We developed and validated a closely matched sham mindfulness intervention then compared it against 6 x 20 - minute sessions of focused - attention mindfulness and a no treatment condition in 93 healthy
volunteers undergoing acute experimental heat
pain . -
pubmed
Infection with respiratory viruses such as
influenza ,
respiratory syncytial virus and coronavirus provides a difficult immunological challenge for the host , where a balance must be established between controlling viral replication and limiting damage to the delicate lung structure . -
pubmed
MATERIALS AND METHODS : Public datasets of
COVID-19 ( N = 130 ) ,
bacterial pneumonia ( N = 145 ) , non - COVID-19
viral pneumonia ( N = 145 ) , and normal ( N = 138 ) CXRs were analyzed . -
pubmed
Although substantial progress has been made over the past 40 years in treating
patients with
cancer , effective therapies for those who are diagnosed with advanced metastatic
disease are still few and far between . -
pubmed
Between 2003 and 2018 , four
patients recorded with
anterior nasal floor perforation with dental implants were followed and reviewed with panoramic radiographs and cone - beam computed tomography . -
pubmed
RESULTS : The most prevalent genotype was
HPV 16 , with an increasing presence depending on the severity of the
CIN and with the highest incidence in the 26 - 35 age range . -
pubmed
A different distribution of
HPV presence was observed depending on
CIN grade ( P<0.001 ): CIN1
HPV negative samples were 46.3 % ,
CIN2 : 5.8 % and
CIN3 : 1.4 % . -
pubmed
Moreover , within
CIN1 , 85 % of them were associated to negative
HPV detection , this observation suggested that the detection of
HPV presence may be useful to identify low
CIN grade that should be reconsidered for surgical treatment . -
pubmed
CONCLUSIONS : These findings suggest implementing the protocol for the management of women with high risk
precancer lesions , with a further
HPV test before surgical treatment . -
pubmed
Tg MSCs administered after the onset of
Escherichia coli - induced
sepsis maintained their ability to improve survival when given in a single dose , in contrast with WT MSCs . -
pubmed
AIMS : Current guidelines recommend surgery within 48 hours among
patients presenting with
hip fractures ; however , optimal surgical timing for
patients on oral anticoagulants ( OACs ) remains unclear . -
pubmed
METHODS : We searched MEDLINE , EMBASE , and the Cochrane Central Register of Controlled Trials ( CENTRAL ) from inception to 14 October 2019 to identify studies directly comparing outcomes among
hip fracture patients receiving direct oral anticoagulants ( DOACs ) or
vitamin K antagonists ( VKAs ) prior to hospital admission to
hip fracture patients not on OACs . -
pubmed
TTS was 13.7 hours longer ( 95 % confidence interval ( CI ) 9.8 to 17.5 ; p < 0.001 ) among
hip fracture patients on OACs compared to those not on OACs . -
pubmed
Evaluating expedited surgical protocols in
hip fracture patients on OACs is an urgent priority , with the potential to decrease morbidity and mortality in this group of high - risk patients . -
pubmed
Temporal lobe epilepsy (
TLE ) is one of the most common and intractable
neurological disorders in
adults . -
pubmed
The induction of
squamous cell carcinomas and
papillomas in a total of 1,950
mice in a lifelong skin - dropping experiment with different doses of automobile exhaust condensate and its fractions is described . -
pubmed
Ciliary arrest in
Phragmatopoma gills was produced by an amount of energy , sufficient to cause a rise in temperature of 150 degrees C in an area of 2 micron3 . -
pubmed
Colonization of the respiratory tract with
Pseudomonas aeruginosa is a serious problem in
cystic fibrosis and seriously ill hospitalized
patients . -
pubmed
Polyamine metabolism in colonic mucosa from
patients with
ulcerative colitis . -
pubmed
Polyamine metabolism in mucosa both from
patients in the active or remission stage of
ulcerative colitis (
UC ) and from healthy controls was studied . -
pubmed
In 22
patients with 1 - year follow - up , IORT prevented local
recurrence in 14 ( 64 % )
patients . -
pubmed
Recovery from
fatigue of
human diaphragm and limb muscles . -
pubmed
This study was designed to compare the recovery from
fatigue of
human inspiratory and limb muscles using repeated maximal static contractions . -
pubmed
Our major conclusions are that the
human diaphragm has a marked capacity to recover from
fatigue and that this may have been underestimated in previous studies from this and other laboratories . -
pubmed
To verify whether
methylmalonic acid accumulates in adult heterozygotes for
inherited methylmalonic - acidaemia and thereby gives " false " positive test results for
cobalamin deficiency , we measured the concentration of
methylmalonic acid in serum and its urinary excretion in six
patients of three
children with severe
methylmalonic - acidaemia . -
pubmed
It also contains a discussion of the origins
pruritus in elderly
people . -
pubmed
The authors discuss the results of surgical treatment of 105
patients with benign
neoplasms of the mediastinum . -
pubmed
The results of complex treatment of 81
patients with
pyoinflammatory diseases with the use of blood ultraviolet irradiation are discussed . -
pubmed
Whole body plasma extravasation in saline and Haemaccel loaded
rats : effects of
endotoxemia . -
pubmed
Are lymphangiograms necessary before placing
patients with nonseminomatous
testicular tumors on surveillance ? -
pubmed
Lymphangiographic findings in 174
patients with early stage nonseminomatous
testicular tumors were evaluated retrospectively to determine the need to perform the procedure before
patients are placed on surveillance . -
pubmed
When physical examination , chest x - ray , computerized tomographic scans and serum
tumor marker levels were normal , lymphangiography detected unsuspected
metastasis in only 4 per cent of the
patients , while providing misinformation in another 4 per cent . -
pubmed
Plain radiographs of 99
patients on surveillance taken at 2 - month intervals resulted in only 1 instance when the x - rays became positive and were the first evidence of
metastasis . -
pubmed
[ Contingent negative variation in normal and
dyslexic children ] . -
pubmed
Nine right handed
boys aged between 9 and 13 years with
reading disabilities were studied . -
pubmed
A study on the anti -
cancer effect of
ningxia wolfberry . -
pubmed
This study has expanded the number of
patients , who were divided into two groups : six
patients with pure
ADHD , and 13
patients with
ADHD in combination with other
neurologic symptoms . -
pubmed
In a
patient receiving
phenytoin who presents a
viral - like illness , early recognition and discontinuation of the drug are mandatory . -
pubmed
From 1976 to 1983 , 28
patients ( 24 male and four female ) with unresectable
hepatocellular carcinoma (
HCC ) were treated by intraarterial chemotherapy at the Istituto Nazionale Tumori of Milan , Milan , Italy . -
pubmed
Systemic
toxicity was mild , but the treatment induced
hepatic toxicity (
ascites , clinical
jaundice , or biochemical impairment ) in 18 % of noncirrhotic and 66 % of cirrhotic
patients . -
pubmed
Clinical reduction of
hepatomegaly was observed in 50 % of noncirrhotic versus 16 % of cirrhotic
patients . -
pubmed
5 - fluorouracil was effective only in
patients without
cirrhosis , with an overall response rate of 22 % . -
pubmed
This study emphasized the negative impact of the treatment on
cirrhotic patients . -
pubmed
A
patient is described in whom , 2 months after an acute
myocardial infarction , inducible
coronary artery spasm and a nonocclusive
thrombus were angiographically demonstrated at the site of a minimal atherosclerotic narrowing in the
infarction - related vessel . -
pubmed
Amnionitis caused by
Propionibacterium acnes . -
pubmed
A
patient with bilateral
pulmonary arteriovenous fistulae is described who was treated successfully by embolization of the two
fistulae with detachable balloons introduced percutaneously through the femoral vein . -
pubmed
The biochemical response to an intravenous
alanine load of 0.25 g / kg was studied in nine adult female relatives of
children with
ornithine carbamoyltransferase deficiency . -
pubmed
Eight
patients from Zaire with
Mycobacterium ulcerans infection were treated by the local application of heat to maintain a temperature of approximately 40 degrees C in the ulcerated area . -
pubmed
[
Pseudomonas aeruginosa infection serotyping . -
pubmed
[ Pressure in the duodenum and effect on it of certain preparations in
patients with
chronic pancreatitis ] . -
pubmed
Group R
streptococcus infections in
man . -
pubmed
The interaction of diet and microflora in experimental
caries in the
rat . -
pubmed
Nifedipine for the poor - risk elderly
patient with
achalasia : objective response demonstrated by solid meal study . -
pubmed
We described an 84 - year - old
woman with symptomatic
achalasia who refused both dilation and surgical treatment . -
pubmed
Hypertension and
proteinuria : long - term sequelae of uninephrectomy in
humans . -
pubmed
Cytotoxic cell activity directed against paternal alloantigens was investigated in primiparous C57BL/10 and CBA / Ca
mice using a
microcytotoxicity assay . -
pubmed
Protective role of dietary
butylated hydroxyanisole against chemical - induced
acute liver damage in
mice . -
pubmed
Prior consumption of a diet containing the food antioxidant ,
butylated hydroxyanisole (
BHA ) , by
female mice prevented the development of or minimized the
acute liver damage caused by
monocrotaline ,
acetaminophen , or
bromobenzene . -
pubmed
The protective effect of
BHA against
acetaminophen - induced
hepatotoxicity was not demonstrated in
male mice . -
pubmed
[ Effect of mechanical
asphyxia on
lipid peroxidation processes in the
rat brain ] . -
pubmed
Repetitive treatment with the organotropic colon carcinogen ,
1,2 - dimethylhydrazine (
DMH ) , produces
tumors in susceptible
mouse strains that exhibit pathological features associated with the
human disease . -
pubmed
As in
human populations , the genetic background of laboratory
animals comprises a significant component to this organ - specific
carcinogenesis , and several
mouse lines , including AKR / J and DBA/2J are highly resistant to the tumorigenic effects of
DMH . -
pubmed
The suspected cause of these
ulcers -- disturbed cutaneous microcirculation -- was studied by simultaneously measuring laser - Doppler flux ( LDF ) and cutaneous
oxygen tension ( pCUO2 ) in 14
patients with DNPU at three differently affected sites ( dorsal forefoot ,
ulcer edge , lower leg ) . -
pubmed
We could detect GFP protein in transgenic
strains and found that its accumulation , conveniently visualized in living
flies using epifluorescence microscopy , was limited to the indirect flight muscles . -
pubmed
Independent of
testosterone ,
ritanserin reduced locomotion and exploration and increased
anxiety in
males , while
DOI increased locomotion and exploration in both sexes . -
pubmed
This report presents five cases of
BFP (
Guillain - Barre syndrome ,
herpes simplex polyneuritis ,
meningeal lymphoma , and two cases of
bilateral Bell ' s palsy ) in which MRI imaging helped in the diagnosis and subsequent management of the
patient . -
pubmed
The appropriate sequence of diagnostic studies for
patients with
BFP is discussed . -
pubmed
In a population of 716
patients with
end - stage renal disease (
ESRD ) , 46
patients ( 6.4 % ) were identified as having
pancreatitis . -
pubmed
The presence of risk factors including age ,
hypertension ,
hypercholesterolemia ,
tobacco use ,
diabetes mellitus and
hyperuricemia were also examined . -
pubmed
In a previous study , we observed that suppression of T - cell proliferation induced by
Salmonella infection is associated with inhibition of
tyrosine phosphorylation in T - cells , and that a cell - free
Salmonella typhimurium LT2 extract ( LT2 extract ) also suppressed mitogen - induced T - cell proliferation . -
pubmed
Reduced humoral immunity in
uremic mice genetically selected for high antibody response . -
pubmed
Osteoporosis is a common disease among
patients undergoing transplantation . -
pubmed
We present a study of 27
women who underwent BMT , all of them suffering
ovarian failure . -
pubmed
Osteopenia was observed in nine
patients ( 33 % ) and
osteoporosis in another five ( 18 % ) , according to the World Health Organization criteria . -
pubmed
We outline a reasonable therapeutic approach for
osteoporosis in BMT emphasizing the need to monitor these
patients after transplantation . -
pubmed
Cystic fibrosis and
non - cystic - fibrosis human nasal epithelium show analogous
Na+ absorption and reversible block by
phenamil . -
pubmed
Transepithelial short - circuit current ( ISC ) , potential ( VT ) and resistance ( RT ) of confluent monolayers of
human nasal epithelium cultured from
patients with and without
cystic fibrosis (
CF ) were measured . -
pubmed
We present two
patients with primary
carcinoid tumor of the pancreas , which metastasized to the liver . -
pubmed
Carcinoid tumor should be considered in the differential diagnosis of a
pancreatic mass in a
patient with
carcinoid syndrome , but lack of this
syndrome does not exclude the diagnosis . -
pubmed
Although
viraemia was detected in the third
horse by virus isolation , from 6 to 14 days after
infection , this animal remained consistently negative by RT - PCR . -
pubmed
Conversely , AHSV viral RNA was detected by RT - PCR in the blood of 4
donkeys and 4 mules up to 55 days after their experimental
infection despite the absence of any detectable infectious virus . -
pubmed
RT - PCR is a sensitive and rapid method for detecting
AHSV nucleic acids during either the incubation period at the start of an
African horse sickness (
AHS ) epizootic , or for epidemiological investigations in species where clinical signs may be inapparent . -
pubmed
A retrospective analysis with a minimum 49 - month follow - up identified 18
patients ( mean age , 61.3 years ) with culture - positive
infections and exposed prosthetic grafts in the infrainguinal region . -
pubmed
It is generally recognized that the initial step in the formation of
atherosclerotic plaque in
humans involves the peroxidation of low density lipoproteins ( LDL ) . -
pubmed
Patient outcome after endovascular treatment of
intracranial aneurysms with reference to microsurgical clipping . -
pubmed
Indications for screening and follow - up of the
patients as limitations and recent achievements of
aneurysm embolization are discussed . -
pubmed
Clinical status of all 15
patients with unruptured
aneurysms preserved . -
pubmed
STUDY DESIGN : Case - control study including 29
patients with
endometriosis and 15 controls . -
pubmed
We report on the clinical manifestations in six affected
individuals from a four - generation family that segregates
brachydactyly type D (
BDD ) . -
pubmed
All affected
individuals have either bilateral and symmetric or
unilateral first distal phalangeal hypoplasia . -
pubmed
Are
heroin overdose deaths related to
patient release after prehospital treatment with
naloxone ? -
pubmed
Results from several studies performed in relevant animal models have demonstrated that
Mycobacterium tuberculosis secreted antigens may represent major components of improved
TB vaccines . -
pubmed
Like
tardive dyskinesia ,
blepharospasm can be disfiguring and aesthetically distressing , contributing to the increased stigmatization of
patients . -
pubmed
CASE REPORTS : We report 4
patients with
DSM - IV schizoaffective disorder ,
paranoid schizophrenia , or chronic
undifferentiated schizophrenia who developed neuroleptic - induced
blepharospasm . -
pubmed
In all
patients ,
blepharospasm remitted without the reemergence of
psychosis within 3 to 5 months of treatment with
clozapine , 100 - 200 mg / day . -
pubmed
CONCLUSION : The results suggest that
clozapine may successfully treat neuroleptic - induced
blepharospasm without the reemergence of
psychosis in
patients with
schizophrenia ,
schizoaffective disorder , or
schizophreniform disorder . -
pubmed
Preclinical validation of this approach is reviewed with the goal of using this immunotherapy for metastatic
human cancers . -
pubmed
CONCLUSIONS : BARI physicians were able to select PTCA rather than CABG for 65 % of registry
patients who underwent revascularization without compromising long - term survival either in the overall population or in treated
diabetics . -
pubmed
By identifying the proteins these genes encode and the mechanisms by which the genes influence an
animal 's biochemical response to
alcohol , scientists can gain insight into the features of
human alcoholism and provide a basis for developing pharmaceuticals that short - circuit these genetically defined processes . -
pubmed
[ Culture of
Plasmodium berghei with the short life span in
mouse erythrocytes : evaluation of
chloroquine resistance in three
strains of the
malaria parasite ] . -
pubmed
These included 1 )
chloroquine - sensitive H
strain ; 2 ) LNK-65
strain having a spontaneously 2 - 3 - fold decreased sensitivity to the agent ; 3 ) strain
LNK-65 ChR selected for high resistance to
chloroquine . -
pubmed
OBJECTIVE : To examine the role of ultrasound versus magnetic resonance imaging ( MRI ) in assessing joint
inflammation in
patients with
juvenile idiopathic arthritis (
JIA ) of the knee . -
pubmed
METHODS : This study was conducted on 38
patients with
juvenile idiopathic arthritis ( 25
girls and 13
boys ) , whose ages ranged between 2 - 17 years ( mean 8 years ) , presenting with
joint swelling ,
tenderness ,
pain on motion and/or limitation of movement . -
pubmed
Skin only or silo closure in the
critically ill patient with an open abdomen . -
pubmed
METHODS : A retrospective review was made of all
trauma or general surgery
patients who underwent an open abdominal closure from January 1997 to December 2000 , at a large urban acute care hospital . -
pubmed
RESULTS : From 1997 to 2000 , 181
patients ( aged 39.8 + /- 16.5 years ) had an open abdomen for
abdominal infection , planned reexploration ,
abdominal compartment syndrome ,
inability to reapproximate fascia , or as part of a " damage control " procedure . -
pubmed
Gastrointestinal fistulas occurred in 26
patients , and 9
patients had a
dehiscence . -
pubmed
Therefore , we enrolled 14
MDS patients ( 4 RA , 2 RARS , 6
RAEB , 2
CMML ) , 44 - 80 ( median 60 ) years old , in a pilot trial . -
pubmed
Thus , etanercept treatment resulted in moderate improvements of
cytopenias in some
patients , while cell counts declined in others . -
pubmed
Communication challenges in a young
man with
Hodgkin ' s disease . -
pubmed
DNA methylation in the
androgen receptor gene promoter region in
rat prostate cancers . -
pubmed
All of the examined
rat prostate and seminal vesicle cancers demonstrated hypermethylation at these
CpG sites . -
pubmed
NTP Toxicology and
Carcinogenesis studies were conducted by administering
furfural ( 99 % pure ) in
corn oil by gavage to groups of
F344 / N rats and
B6C3F1 mice of each sex for 16 days , 13 weeks , or 2 years . -
pubmed
Genetic toxicology studies were conducted in
Salmonella typhimurium ,
mouse lymphoma cells ,
Chinese hamster ovary ( CHO ) cells ,
Drosophila melanogaster , and
mouse bone marrow cells . -
pubmed
Final mean
body weights of chemically exposed
animals were similar to those of vehicle controls ; no compound - related histologic lesions were observed in any dosed groups . -
pubmed
Most
rats that received 180 mg / kg died ; mean
body weights of chemically exposed
rats were similar to those of vehicle controls . -
pubmed
Mean
body weights of chemically exposed
mice were similar to those of vehicle controls throughout the studies . -
pubmed
Mean absolute liver weights and liver weight to
body weight ratios were increased in
females that received 300 mg / kg . -
pubmed
Centrilobular coagulative
necrosis and/or multifocal subchronic
inflammation of the liver were present in chemically exposed
mice but not in vehicle control
mice . -
pubmed
Body Weight and Survival in the Two - Year Studies : Mean
body weights of chemically exposed and vehicle control
animals were similar throughout the studies for
rats and
mice . -
pubmed
Survival of high dose female
rats was reduced by
deaths associated with gavage administration ; the administration of
furfural was considered to be a contributing factor in these gavage - related
deaths . -
pubmed
Nonneoplastic and Neoplastic Effects in the Two - Year Studies : Centrilobular
necrosis of the liver occurred at increased incidences in chemically exposed male
rats ( vehicle control , 3/50 ; low dose , 9/50 ; high dose , 12/50 ) . -
pubmed
Two high dose
male rats had
bile duct dysplasia with
fibrosis , and two had
cholangiocarcinomas ; neither lesion was seen in the other dose groups . -
pubmed
The historical incidence of
bile duct neoplasms in
corn oil vehicle control male
rats is 3/2,145 ( 0.1 % ) . -
pubmed
Multifocal pigmentation and chronic
inflammation of the subserosa of the liver occurred in chemically exposed
mice ( pigmentation -- male : 0/50 ; 0/50 ; 8/49 ; 18/50 ; female : 0/50 ; 0/50 ; 0/50 ; 11/50 ;
chronic inflammation -- male : 0/50 ; 0/50 ; 8/49 ; 18/50 ; female : 0/50 ; 0/50 ; 1/50 ; 8/50 ) . -
pubmed
The incidences of
hepatocellular adenomas and
hepatocellular carcinomas in
male mice and
hepatocellular adenomas in female
mice were significantly increased in the high dose group compared with those in the vehicle controls ( male --
adenomas : 9/50 ; 13/50 ; 11/49 ; 19/50 ;
carcinomas : 7/50 ; 12/50 ; 6/49 ; 21/50 ; female --
adenomas : 1/50 ; 3/50 ; 5/50 ; 8/50 ;
adenomas or
carcinomas , combined : 5/50 ; 3/50 ; 7/50 ; 12/50 ) . -
pubmed
Three
renal cortical adenomas or
carcinomas occurred in chemically exposed male
mice ( 0/50 ; 1/50 ; 1/49 ; 1/50 ) , and a
renal cortical adenoma was present in one low dose female
mouse ; the historical incidence oal incidence of
renal cortical neoplasms in National Toxicology Program 2 - year
corn oil gavage studies in male
B6C3F1 mice is 8/2,183 . -
pubmed
Forestomach
hyperplasia occurred in chemically exposed female
mice , and
squamous cell papillomas were increased in high dose female
mice (
hyperplasia : 0/50 ; 5/50 ; 5/50 ; 3/50 ;
papillomas : 1/50 ; 0/50 ; 1/50 ; 6/50 ) . -
pubmed
melanogaster ;
furfural did not induce SCEs or
chromosomal aberrations in the bone marrow of
B6C3F1 mice . -
pubmed
Conclusions : Under the conditions of these 2 - year gavage studies , there was some evidence of carcinogenic activity of
furfural for male
F344 / N rats based on the occurrence of uncommon
cholangiocarcinomas in two
animals and
bile duct dysplasia with
fibrosis in two other
animals . -
pubmed
There was clear evidence of carcinogenic activity for male
B6C3F1 mice , based on increased incidences of
hepatocellular adenomas and
hepatocellular carcinomas . -
pubmed
There was some evidence of carcinogenic activity in female
B6C3F1 mice , based on increased incidences of
hepatocellular adenomas . -
pubmed
Renal cortical adenomas or
carcinomas in
male mice and
squamous cell papillomas of the forestomach in female
mice may have been related to exposure to
furfural . -
pubmed
BACKGROUND / AIMS : To compare two non - invasive techniques of assessing
wound healing , photography and high resolution ultrasound ( HRUS ) scanning , in experimentally induced full - thickness
human skin
wounds . -
pubmed
METHODS : Punch biopsy
wounds , 4 mm in diameter , were made aseptically through locally anaesthetised skin on the anterior ( volar ) surface of the non - dominant forearm , 3 cm below the base of the cubital fossa , of 20
human participants . -
pubmed
However most forms of
human obesity do not appear to entail elevated plasma glucocorticoids . -
pubmed
Twenty - five
patients with a prominent
zygoma underwent reduction malarplasty from January 1995 through January 2001 . -
pubmed
Immunophenotypic and viral (
human papillomavirus ) correlates of
vulvar seborrheic keratosis . -
pubmed
In recent years ,
HPV has been detected in vulvar epithelial changes lacking
koilocytosis , including
squamous papillomas and lesions closely resembling
seborrheic keratosis (
SK ) . -
pubmed
Eighteen of 25
VSKs ( 72 % ) , 0 of 10 nondiagnostic vulvar acanthuses ( 0 % ; P = 0.0001 ) , 2 of 12
FEPs ( 16.7 % ; P = 0.004 ) , and 3 of 20
CSKs ( 15 % ; P = 0.0002 ) scored
HPV positive . -
pubmed
MATERIALS AND METHODS : We reviewed frozen section examination of the resection surfaces of 131 consecutive
patients surgically treated for
squamous cell carcinoma of the lower lip during the period January 1980 to January 1999 . -
pubmed
In 8
patients ( 6 % ) , a local
recurrence developed . -
pubmed
In this multicenter study , performed in emergency departments , 130
patients with acute
respiratory failure were randomized to receive medical therapy plus
O2 ( 65
patients ) or noninvasive pressure support ventilation ( 65
patients ) . -
pubmed
Noninvasive pressure support ventilation does , however , reduce the intubation rate in the subgroup of
hypercapnic patients . -
pubmed
[ First cases of
dermatophytosis caused by
Microsporum audouini in Bosanska Krajina ] . -
pubmed
A kinetic study of
local lesion growth on
Nicotiana glutinosa resulting from
tobacco mosaic virus infection . -
pubmed
Chromatographic separations on DEAE cellulose have been carried out on the seromucoid fraction from forty - one normal individuals and twenty - three
patients horpitalized with unilateral
pneumococcal pneumonia . -
pubmed
The seromucoid pattern of seven
patients with
acute leukemia differed from that of the control groups and also differed from that observed in patients with
pneumonia . -
pubmed
We report a
patient with a sufficiently thick cornea ( 593 microm ) and no topographic signs of
keratoconus preoperatively who developed iatrogenic
keratoconus 2 months after repeat laser in situ keratomileusis ( -4.00 -1.00 x 20 ) performed 5 months after the primary procedure ( -10.50 -1.00 x 55 ) . -
pubmed
This technique has been performed in 67
patients harboring
sellar and parasellar lesions . -
pubmed
Precipitation reaction of the sera obtained from the
patients of various types of
pulmonary infection against anti - lung - tissue immune serum and anti - pulmonary - cavity content immune serum . -
pubmed
EHS
tumor arose spontaneously in an ST / Eh strain
mouse and has been propagated by transplantation . -
pubmed
Clinical predictors in
obstructive sleep apnoea patients with calibrated cephalometric analysis -- a new approach . -
pubmed
Concomitant
infection with streptococci and
C. - pubmed
Bleeding , temporary
renal failure , acute
respiratory distress syndrome , and graft
infection occurred in one
patient each ; all recovered from these complications . -
pubmed
Although preclinical data suggest that new drugs can modulate or slow prostate
tumor proliferation , responses in
man , such as disease stabilization or regression , are not as dramatic as those seen in preclinical models . -
pubmed
Comparison of left ventricular and biventricular pacing in
patients with
heart failure . -
pubmed
Our case indicates that
myomatous uterus in premenopausal
women shows the potential pitfall of a positive result of
FDG - PET . -
pubmed
OBJECTIVE : To investigate the effectiveness and complication rate of intravaginal
gemeprost , a
prostaglandin E ( 1 ) analogue , for second - trimester pregnancy termination in
women with a
scarred uterus . -
pubmed
RESULTS : The rate of successful abortions among
women with
uterine scars was not different from that observed in the nulliparous controls , but previously vaginal delivery was associated with a shorter induction to abortion interval . -
pubmed
OBJECTIVE : To evaluate associations linking glucocorticoid dose changes in
patients with
polymyalgia rheumatica (
PMR ) to the PMR activity score ( PMR - AS ) and its components . -
pubmed
A
rat osteoporotic spine model for the evaluation of bioresorbable bone cements . -
pubmed
To further test this hypothesis , a suitable
animal model is needed to evaluate the in vivo behavior of potential biomaterials in
osteoporotic bone . -
pubmed
CONCLUSIONS : Future investigation of potential biomaterials intended for the local treatment of
osteoporosis will require their study within an appropriate
osteoporosis animal model . -
pubmed
The effectiveness of ureteric reimplantation during bladder augmentation for high - grade
vesicoureteric reflux in
patients with
neurogenic bladder : long - term outcome . -
pubmed
PURPOSE : The outcome of ureteric reimplantation ( UR ) during bladder augmentation ( BA ) for high - grade
vesicoureteric reflux (
HVUR ) in
patients with
neurogenic bladder was assessed to determine the effectiveness of UR . -
pubmed
METHODS : Twenty - two consecutive sigmoidocolocystoplasty
patients were reviewed retrospectively ; 10 had unilateral HVUR only , 3 had bilateral
HVUR , and 9 had unilateral
HVUR associated with low - grade
VUR in the contralateral renal unit ( RU ) . -
pubmed
Urinary tract infection , universal preoperatively , was seen postoperatively in only 2
patients . -
pubmed
CONCLUSIONS : Ureteric reimplantation during BA is safe and effective for treating
HVUR in
patients with
neurogenic bladder . -
pubmed
This meta - analysis aimed to assess the middle - term outcomes after crural angioplasty in
patients with
chronic critical limb ischemia and compare results with a meta - analysis of popliteal - to - distal vein bypass graft . -
pubmed
Two - year follow - up of splenic radiofrequency ablation in
patients with
cirrhotic hypersplenism : does increased hepatic arterial flow induce liver regeneration ? -
pubmed
Since the introduction of radiofrequency ablation ( RFA ) for
patients with
cirrhotic hypersplenism , we observed a phenomenon of visible hepatic regeneration . -
pubmed
METHODS : Forty
patients who underwent splenic RFA for cirrhotic
hypersplenism were followed for 24 months . -
pubmed
Patients with & gt ; or = 40 % of spleen volume ablated had better improvement of
thrombocytopenia . -
pubmed
A 16 - year - old
man had a
traumatic accident during motor - cross racing and sustained an anterior
hip dislocation with
fracture of anterior superior and anterior inferior iliac spines . -
pubmed
The
valgus instability of 24
patients ( 12 isolated
injuries and 12
multiple ligament injuries ) who suffered
MCL injury between 1993 and 1998 was evaluated with the Hughston and Eilers classification , which involves radiographic assessment under manual valgus stress to the injured knees . -
pubmed
The results of the study show that
iodine supplementation to weaner , non -
iodine deficient euthyroid
rats at 3ppm not only retard
weight gain but could also reduce fertility by lowering epididymal sperm counts . -
pubmed
Reversal of
cadmium - induced
thyroid dysfunction by
selenium ,
zinc , or their combination in
rat . -
pubmed
The aim of this study was to evaluate the potential benefit of combined treatment with
zinc (
Zn ) and
selenium (
Se ) in reversing
cadmium (
Cd)-induced
thyroid dysfunction compared to
Se or
Zn treatment alone in
rats exposed to
Cd . -
pubmed
The treatment of
Cd - exposed
animals with
Zn alone partially protected against
Cd - induced
thyroid dysfunction by maintaining normal RTW and by decreasing
Cd concentration in the thyroid . -
pubmed
STUDY DESIGN : Between January 1 , 1977 , and December 31 , 2006 , 142
patients with high - risk metastatic
GTN were treated . -
pubmed
Hysterectomy was performed in 42 of 142 high - risk
patients ;
metastases were resected in 26 of 142 of high - risk
patients . -
pubmed
CONCLUSION : Results support that
patients with high - risk metastatic
GTN should primarily be treated with combination chemotherapy . -
pubmed
This study was to investigate its antitumor effects on
tumor cell xenografts in
mice . -
pubmed
METHODS : The inhibitory effects of
raddeanin A on the proliferation of
human nasopharyngeal carcinoma KB cells and
ovarian cancer SKOV3 cells were measured by
MTT assay . -
pubmed
The inhibitory effects of
raddeanin A injection on the growth of
sarcoma S180 ,
liver cancer H22 and
cervical carcinoma U14 cell xenografts in
mice and the effect of
raddeanin A lavage on the growth of
S180 cell xenografts were measured . -
pubmed
METHODS : From 16
patients , we obtained paired fine needle aspiration biopsies ( FNABs ) of
breast cancers taken before ( PRE ) and after ( POST ) their surgeries and compared the microarray data to determine the genes that were differentially expressed between the FNABs taken at the two time points . -
pubmed
All
patients underwent DSAEK for
Fuchs endothelial dystrophy ,
pseudophakic bullous keratopathy ,
aphakic bullous keratopathy , failed graft , or
iridocorneo endothelial syndrome . -
pubmed
Tobacco smoking has wide spread systemic effects , many of which may provide mechanisms for the increased susceptibility to
periodontitis and the poorer response to treatment . -
pubmed
CONCLUSION :
Tobacco smoking is a significant risk factor for
periodontal disease . -
pubmed
Multiple and simultaneous intraatrial bipolar recordings from 27
patients in
AF were analyzed before and after infusing a
propofol bolus . -
pubmed
The status of
rainbow trout genetic maps has progressed significantly over the last decade due to interest in this species in aquaculture and sport fisheries , and as a model research organism for studies related to
carcinogenesis , toxicology , comparative immunology , disease ecology , physiology and nutrition . -
pubmed
BACKGROUND AND OBJECTIVES : Observational studies have reported earlier onset of
psychosis in
schizophrenic patients with a history of cannabis use . -
pubmed
We aimed to examine whether cannabis use determined an earlier onset of
schizophrenia in a sample of first episode
patients , in an area with one of Europe 's highest rates of cannabis use . -
pubmed
Transgenic
mouse models of
human diseases have gained increasing importance in the pathophysiology of
cardiovascular diseases (
CVD ) . -
pubmed
The existing imaging literature on the neurobiological correlates of fear processing and
anxiety disorders points to a pivotal role of the amygdala in the
human fear circuit . -
pubmed
Longitudinal studies in
patient samples will be required to elucidate how genetically influenced neurobiological intermediate phenotypes are associated with subtype , severity and the course of
anxiety disorders , thereby having the potential for developing individualized therapy regimes derived from neurobiological research . -
pubmed
METHODS : A 70 % hepatic reperfusion model of
rats was established , setting groups of sham - operation and
injury ones with different reperfusion time . -
pubmed
The findings of our case suggest that for a
neurofibromatosis 1 patient , a good prognosis can be expected even if a huge destructive intrathoracic intrusion is detected . -
pubmed
We will discuss the definition , diagnosis , and treatment of
patients with atypical
meningioma ; review the current phase II cooperative trials ; and draw attention to some questions timely for pre - clinical and clinical research . -
pubmed
Early assessment of treatment response in
patients with
AML using
[ ( 18 ) F ] FLT PET imaging . -
pubmed
We investigated the use of positron emission tomography ( PET ) for early assessment of treatment response in
patients with
acute myeloid leukemia (
AML ) , using the proliferation marker
3 '- deoxy-3 '-[( 18 ) F ] fluoro - l - thymidine (
FLT ) . -
pubmed
In the trial group (
patients having remnant ACL , n = 38 ) , there were 27
males and 11
females with an average age of 24.3 years ( range , 16 - 43 years ) ; of them , 8 cases complicated by
meniscus injury and 13 cases by Outbridge I degree
cartilage injury ; the time from
injury to operation was 3 - 20 weeks ( mean , 8.6 weeks ) . -
pubmed
In the control group (
patients having no remnant ACL , n = 59 ) , there were 35
males and 24
females with an average age of 27.8 years ( range , 18 - 48 years ) ; of them , 16 cases complicated by
meniscus injury and 23 cases by Outbridge I degree
cartilage injury ; the time from
injury to operation was 4 - 44 weeks ( mean , 12.7 weeks ) . -
pubmed
Knee instability disappeared ; the
patients showed negative anterior drawer test and negative Lackman test . -
pubmed
METHODS : A multicenter , inter - group , cross - sectional study was conducted in 905 adult symptomatic
patients with JC
pollinosis to investigate the Japanese
Allergic Rhinitis Standard QOL Questionnaire ( JRQLQ ) . -
pubmed
Giant
atrial myxoma mimicking severe
mitral stenosis in young
patient . -
pubmed
The echocardiogram of a twenty - year - old
man , previously healthy , suffering from
paroxysmal nocturnal dyspnea and
fatigue after moderate exertion that intensified over a period of about ten days , showed the left atrium
myxoma working as severe
mitral stenosis . -
pubmed
Despite rapid advances in
cancer diagnosis and treatment ,
pancreatic cancer remains one of the most difficult
human malignancies to be treated , with a mortality rate nearly equal to its incidence . -
pubmed
These secondary lesions are responsible for significant impairment of quality of life of
patients with onset of
pain , which is frequently resistant to standard analgesics . -
pubmed
The therapeutic challenge for a
patient with spinal
metastasis is to maintain a quality of life as good as possible , commensurate with its life expectancy . -
pubmed
Stereotactic radiosurgery could be provided for
patients with single lesions or
oligometastatic disease , a good general condition , absence of
cord compression , and a life expectancy greater than 6 months . -
pubmed
Decreased axonal density and altered expression profiles of axonal guidance genes underlying lead (
Pb )
neurodevelopmental toxicity at early embryonic stages in the
zebrafish . -
pubmed
Previous studies have reported that environmental lead (
Pb ) exposure can result in
neurological alterations in
children leading to reduced IQ ,
attention deficit hyperactivity disorder , and
diminished reading and learning abilities . -
pubmed
The intensities of
infection by
P. - pubmed
There is limited to moderate evidence to support improvements in dynamic postural stability , and
patient perceived functional stability through neuromuscular training in subjects with
CAI . -
pubmed
Infection by hepatitis B virus (
HBV ) and dietary exposure to
aflatoxin B ( 1 ) (
AFB ( 1 ) ) are the main risk factors for the development of
chronic liver disease and
hepatocellular carcinoma (
HCC ) . -
pubmed
OBJECTIVE :
Refractory schizophrenia (
SZ ) affects approximately 30 % of
people with
SZ . -
pubmed
Why do
human phobias last for months or years when such behavior should undergo extinction ? -
pubmed
This failure of extinction or persistence of self - defeating behavior of
human disorders was labeled by Mowrer as the
neurotic paradox . -
pubmed
, implosive therapy ) are combined with ( b ) principles examined in laboratory research that are combined to generate unique predictions that correspond to known features of
human phobic behavior . -
pubmed
This combination of factors effectively precludes extinction to main conditioned aversive stimuli for
nonhumans , as it does for
human phobias . -
pubmed
Support for a laboratory model of
human phobia is thereby attained . -
pubmed
To search for a better strategy for the prevention and treatment of
KD , this study compared and validated
human KD immunopathogenesis in a
mouse model of
Lactobacillus casei cell wall extract ( LCWE)-induced
coronary arteritis . -
pubmed
Blood samples from
KD patients were collected before and after IVIG treatment , and
cardiovascular abnormalities were examined by transthoracic echocardiography . -
pubmed
Wild - type male BALB / c
mice ( 4 - week - old ) were intraperitoneally injected with
LCWE ( 1 mg / mL ) to induce
coronary arteritis . -
pubmed
Glucose metabolism and diabetogenic gene expression analysis of
chloroform fraction of
Andrographis paniculata ( Nees ) whole herb in
diabetic albino
mice . -
pubmed
The aim of the present work was to analyze the anti - diabetic potential of
chloroform fraction of
ethanol extract of
Andrographis paniculata ( AP ) and
diabetes laden gene expression alteration . -
pubmed
In
diabetic mice , the fraction reduced the level of harmful
cholesterol , while increased the favorable
cholesterol significantly . -
pubmed
MATERIALS AND METHODS : Serum samples from 30 adult
patients ( 22
males and 8
females , median age 37 , range 19 - 66 years ) with
AML had been taken before chemotherapy was administered . -
pubmed
Ten samples from healthy
normal persons of matched age and sex were evaluated as a reference control group . -
pubmed
The treatment of
dermatophytoses due to
Microsporum canis is cumbersome and
relapses can occur . -
pubmed
Volatile essential oils ( EOs ) obtained from plants would seem to represent suitable tools to contrast
mycoses both in
human and animals . -
pubmed
difficile
strains were subjected to the broth dilution method to determine minimum inhibitory concentrations ( MIC ) and minimum bactericidal concentrations ( MBC ) for
Manuka honey . -
pubmed
difficile
strains , in which increasing concentrations of
Manuka honey resulted in increasing size of zone of inhibition formed . -
pubmed
difficile is appreciably susceptible to
Manuka honey and this may offer an effective way of treating
infections caused by the organism . -
pubmed
This serovar appears to affect men who have sex with men ( MSM ) , most of them being co - infected with the
Human Immunodeficiency Virus (
HIV ) . -
pubmed
The present study addressed the role of HA matrix for progression and prognosis of
human bladder cancer by studying the expression and function of HA - related genes . -
pubmed
METHODS : Tissue samples of 120
patients with different stages of
transitional cell bladder cancer , who underwent surgical treatment for
bladder cancer at the University Hospital of Essen were analysed . -
pubmed
CONCLUSIONS : PK evaluation may help identify
adolescents at risk of excessive
DMPA - associated
weight gain . -
pubmed
OBJECTIVE : To analyze the relationship between
birth weight and
elevated blood pressure among
schoolchildren aged 6 - 11 years in 8 provinces of China . -
pubmed
CONCLUSION : Current
BMI but not
birth weight was found to be a strong determinant of
elevated blood pressure among
children aged 6 - 11 years in China . -
pubmed
This is a case report of
odontogenic myxoma in a 32 year old female
patient and the treatment rendered to her . -
pubmed
Atorvastatin decreases
inflammation and thrombogenesis in
patients with
carotid artery plaque . -
pubmed
Eighty - nine
patients from northeastern China with
acute ischemic stroke caused by large - artery
atherosclerosis were randomly divided into the study and control groups . -
pubmed
These results suggest that
atorvastatin reduces
inflammation and thrombogenesis independent of its lipid - lowering effects in
patients with
acute ischemic stroke caused by large - artery
atherosclerosis . -
pubmed
Bacteriophage J-1 was isolated in 1965 from an abnormal fermentation of Yakult using
Lactobacillus casei strain Shirota , and a related phage , PL-1 , was subsequently recovered from a
strain resistant to J-1 . -
pubmed
This preliminary study sought to analyze the effects of a training program based on the Proprioceptive Neuromuscular Facilitation ( PNF ) method on motor recovery of
individuals with chronic
post - stroke hemiparesis . -
pubmed
Here we report the case of a 37 - year - old
patient with
ENS and severe functional impairment , who was diagnosed with a
somatic symptom disorder and treated accordingly . -
pubmed
At month 6 , the
patient was displaying back - to - normal levels of functioning and was no longer seeking care for
ENS . -
pubmed
RESULTS : Of 249
patients enrolled , 171 showed
thrombus on baseline computed tomography . -
pubmed
In 34
patients ( 19.9 % , nonvolume reduction ; either no change or
thrombus volume increased ) , overall
thrombus volume increased . -
pubmed
In the placement of these devices particular attention and effort must be made to understand safe and reliable anatomic techniques and device maintenance so as to avoid serious
injury to the
patient . -
pubmed
Human adipose tissue expansion in pregnancy is impaired in
gestational diabetes mellitus . -
pubmed
This study aimed to investigate
human AT expandability during pregnancy and its role in the pathogenesis of
gestational diabetes mellitus (
GDM ) . -
pubmed
METHODS : All
patients with severe and severe / complicated
CDI refractory to oral
vancomycin + - rectal
vancomycin and intravenous
metronidazole therapy were offered FMT . -
pubmed
Of the two
patients who died within 30 days , one underwent colectomy and succumbed to
sepsis ; the other died from
septic shock related to
CDI . -
pubmed
Patient was diagnosed with
midventricular SCM . -
pubmed
Comparison of
quercetin and
resveratrol in the prevention of
injury due to testicular torsion / detorsion in
rats . -
pubmed
We compared their effects in
testicular torsion / detorsion ( T / D ) in adult
rats . -
pubmed
This study investigates the potential disruptions in prefrontal - hippocampus structural and functional connectivity , as well as their relationship in first - episode medication - naive
adolescents with
MDD in order to investigate the early stage of the illness without confounds of illness course and medication exposure . -
pubmed
METHODS : Diffusion tensor imaging and resting - state functional magnetic resonance imaging ( rs - fMRI ) data were acquired from 26 first - episode medication - naive
MDD adolescents and 31 healthy controls ( HC ) . -
pubmed
PATIENTS AND METHODS : A trained professional conducted a periodontal examination in 40
patients with
RA aged 23 to 73 years ( 85 %
women ) . -
pubmed
RESULTS : Thirty five of the 40
patients had
periodontitis and in 13 , it was severe . -
pubmed
Patients using higher doses of
corticosteroids had lower severity of
periodontitis . -
pubmed
CONCLUSIONS :
Periodontitis is common and severe in
patients with
RA , and is influenced by gender , age , smoking and
corticosteroid dose . -
pubmed
METHODS : Serial pharmacokinetic / pharmacodynamic measurements and Sieving coefficients were assessed in two
patients with severe
influenza B infection requiring organ replacement therapy . -
pubmed
RESULTS :
Patient # 1 , a 9 - year - old female with severe
influenza B virus infection , biventricular assist device , and continuous veno - venous hemodiafiltration , received 75 mg oral
oseltamivir twice - daily for 2 days , then intravenous
oseltamivir with one - time renoprotective dosing ( 40 mg ) , followed by regular intravenous administration of 100 mg twice - daily . -
pubmed
Patient # 2 , a 28 - year - old female with
influenza B virus infection requiring extracorporeal membrane oxygenation , received 75 mg oral
oseltamivir twice - daily , resulting in erratic
oseltamivir blood concentrations . -
pubmed
Evidence - based pediatric dosing recommendations and effective intravenous antiviral treatment modalities are needed for intensive care
patients with life - threatening
influenza disease . -
pubmed
Role of
Berberine in the Treatment of
Methicillin - Resistant
Staphylococcus aureus Infections . -
pubmed
These findings will provide new insights into the multiple pharmacological properties of
berberine in the treatment of
microbial - generated
amyloid involved diseases . -
pubmed
Recent studies have identified impairments in neural induction and in striatal and cortical neurogenesis in
Huntington ' s disease (
HD ) knock - in
mouse models and associated embryonic stem cell lines . -
pubmed
The triple - negative
breast cancer (
TNBC ) is a very aggressive
tumor type often occurring in young women and is associated with a bad prognosis for the
patients . -
pubmed
BACKGROUND :
Pruritus is the hallmark clinical sign of
atopic dermatitis (
AD ) in
dogs . -
pubmed
ANIMALS :
Clinicians at 15 referral clinics enrolled 211 client owned
dogs with a history of
chronic AD . -
pubmed
Dog owners assessed visual analog scale ( VAS ) scores of
pruritus on days 0 , 1 , 2 , 3 , 7 , 14 , 21 , 28 , 35 , 42 , 49 and 56 . -
pubmed
Clinicians assessed
Canine AD Extent and Severity Index ( CADESI-03 ) scores on days 0 , 7 , 14 , 28 , 42 and 56 . -
pubmed
Further studies are needed to better understand variability in individual responses across a broader population of
dogs with
AD . -
pubmed
cremoris IBB477
strain , previously shown to persist in the gastrointestinal tract of germ - free
rats . -
pubmed
Rhizobium radiobacter in
pulmonary abscess associated with postgripal necrotizing
pneumonia . -
pubmed
Although in the last years
poliovirus (
PV ) transmission has been reported at the lowest levels ever recorded , the spread of virus from endemic countries endures ; the high levels of immigration flows across the Mediterranean Sea jeopardize Italy for
PV reintroduction . -
pubmed
In addition , the Environmental Surveillance ( ES ) , seeking the presence of
PV and Non - Polio Enterovirus (
NPEV ) in sewage , is recognized as a powerful tool to confirm
PV circulation in absence of
AFP cases , especially in
polio - free countries . -
pubmed
The aim of this study was to review the outcomes of a series of
breast cancer patients who underwent sentinel node biopsy inclusive of lymphoscintigraphy , and to assess the incidence of internal mammary node ( IMN ) metastatic positivity at exploration and whether these findings influenced treatment . -
pubmed
METHODS AND RESULTS :
Pigs implanted with single - chamber implantable cardioverter defibrillators to record
ventricular arrhythmias (
VAs ) were subjected to percutaneous
coronary occlusion to induce
myocardial infarction . -
pubmed
OBJECTIVE : To determine the long - term safety and outcomes of mesenchymal stem cells ( MSCs ) for
bronchopulmonary dysplasia in premature
infants enrolled in a previous phase I clinical trial up to 2 years of corrected age ( CA ) . -
pubmed
In the present study ,
patients with unprovoked late - onset
seizures and without known
neoplasm , who might have had
paraneoplastic encephalitis , were investigated for a potentially underlying autoimmunity . -
pubmed
METHODS : Sixty - six consecutive
patients ( 36
women ; aged & gt;=55 years ) after having at least one
seizure or
seizures for & lt;=6 months were prospectively identified over a period of 4.75 years . -
pubmed
SIGNIFICANCE : Our findings suggest that
autoimmunity should be considered an important etiology in
patients with late - onset
seizures . -
pubmed
Task - Specific and Functional Effects of Speed - Focused Elliptical or Motor - Assisted Cycle Training in
Children With Bilateral
Cerebral Palsy : Randomized Clinical Trial . -
pubmed
METHODS : A total of 27
children with bilateral
CP , 5 to 17 years old , were randomized to 12 weeks of 20 minutes , 5 days per week home - based training ( elliptical = 14 ; cycle = 13 ) at a minimum of 40 revolutions per minute , with resistance added when speed target was achieved . -
pubmed
RESULTS : The adrenal medulla of the HFD
rats showed prominent structural changes , such as
hypertrophy of chromaffin and
ganglion cells , vacuolation ,
inflammatory foci , and
fibrosis . -
pubmed
A fundamental issue is to understand the residual capacity of those
LBD patients in tool selection . -
pubmed
METHODS : Three
LBD patients with tool use disorders , three right brain - damaged (
RBD )
patients , and six matched healthy controls performed a novel tool selection task , consisting in extracting a target out from a box by selecting the relevant tool among eight , four , or two tools . -
pubmed
By using positron emission tomography , our study demonstrated neuroinflammation in the brain of
patients with
ME /
CFS . -
pubmed
Neuroinflammation was found to be widespread in the brain areas of the
patients with
ME /
CFS and was associated with the severity of their neuropsychological symptoms . -
pubmed
We investigated in a
rodent model of
intrauterine growth restriction (
IUGR ) induced by maternal protein restriction ( R ) during gestation which time window of
maternal undernutrition ( gestation , lactation or gestation - lactation ) has more impact on the male offspring metabolomics phenotype . -
pubmed
In contrast ,
IUGR rats displayed permanently impaired beta - oxidation , associated to increased
glucose or
BCAA oxidation at adulthood , depending on the fact that pups experienced slow postnatal or catch - up growth , as suckled by R or C dams , respectively . -
pubmed
Analysis of 246 sentinel lymph node biopsies of
patients with clinical primary
breast cancer by application of
carbon nanoparticle suspension . -
pubmed
Successful retrograde recanalization of acute right dominant
vertebral artery occlusion through the left posterior communicating artery in a
patient with acute
vertebrobasilar ischemic stroke . -
pubmed
Infertile
women have a high incidence of latent
GTB and treatment improves fertility outcomes . -
pubmed
Group I consisted of infertile
women with proven tubal patency but with latent
GTB diagnosed by DNA PCR testing of an endometrial biopsy . -
pubmed
Postoperative complications and 90 - day mortality in radical cystectomy in high - risk
patients : A monocentric retrospective observational study . -
pubmed
AIM : Assessing the incidence of immediate
postoperative complications and 90 - day mortality in high - risk
patients who have undergone radical cystectomy ; evaluating the correlation between preoperative conditions and surgery outcomes . -
pubmed
In 28 % of
patients , no complications arose , while in 46 % grades I - II complications according to Clavien - Dindo occurred , in 23 % grades III - IV complications occurred , and in 3 % of the
patients ,
death arose in the immediate postoperative period ( grade V ) . -
pubmed
The HA stalk - specific antibody response is associated with protection from homologous , heterologous , and heterosubtypic
influenza virus infection in
mice . -
pubmed
Restoring vasculogenic potential of endothelial cells from
diabetic patients through spheroid formation . -
pubmed
Among other issues ,
patients with
diabetes suffer from diminished endothelial cell ( EC ) function , which contributes to impaired vasculogenesis and recovery from ischemic insult . -
pubmed
Methods : We hypothesized that forming
human microvascular endothelial cells ( HMVECs ) from
diabetic patients into spheroids would restore their vasculogenic potential following upregulation of these cell - cell interactions . -
pubmed
Results : Individual HMVECs from
diabetic patients exhibited similar proliferative and chemotactic potential to cells from healthy donors but reduced tubulogenesis . -
pubmed
This study demonstrates a promising approach for restoring the diminished vasculogenic potential of endothelial cells in
diabetic patients . -
pubmed
The current study aimed to investigate the modulatory effects of
amitriptyline on
bleomycin - induced
pulmonary fibrosis in
rats . -
pubmed
In the
nude mice ,
THZ2 also suppressed the growth of xenograft
tumors of
gastric cancer . -
pubmed
A virus was readily transmitted mechanically from young leaves of each of the two ilarvirus - negative trees to
Chenopodium quinoa and
Nicotiana occidentalis strain ' 37B ' , which within 5 days , developed systemic mottle and
necrotic flecking , respectively . -
pubmed
METHODS : In this retrospective chart review , we evaluated our cohort of
patients treated with a treatment paradigm for
CNV in
AMD . -
pubmed
A 74 - year - old
diabetic man with prior right total knee arthroplasty and
MRSA infection presented with persistent
bacteremia and
sepsis . -
pubmed
RATIONALE AND OBJECTIVES : Requests for gastrostomy tube placement in
patients on
aspirin (
ASA ) 325 mg are common , particularly in
patients following reconstructive surgery for
head and neck cancer , but periprocedural guidelines and recommendations regarding management of high dose
aspirin are inconsistent . -
pubmed
The purpose of this study was to assess the
bleeding risk of percutaneous gastrostomy tube placement in
patients on
ASA 325 mg . -
pubmed
MATERIALS AND METHODS : This retrospective study of 213
patients who underwent image - guided " push " percutaneous gastrostomy tube placement compared rates of significant
bleeding and other secondary outcomes ( including all - cause mortality within 30 days , procedure - related mortality ,
bowel perforation ,
abdominal abscess ,
peritonitis ,
aspiration pneumonia , intraprocedural
airway complications , and
tube dislodgement ) between
patients maintained on
ASA 325 mg and
patients not on antiplatelet or anticoagulation therapy . -
pubmed
RESULTS : No significant
bleeding episodes occurred in
patients on
ASA 325 mg , compared to three episodes in
patients not on
ASA 325 mg ( p = 0.37 ) . -
pubmed
A
patient in each group had aspiration
pneumonia possibly related to tube placement . -
pubmed
Response to the Rechallenge With Talimogene Laherparepvec ( T - VEC ) After Ipilimumab / Nivolumab Treatment in
Patient With Cutaneous
Malignant Melanoma Who Initially Had a Progression on T - VEC With Pembrolizumab . -
pubmed
An 83 - year - old
man developed a
subungual lesion of the left thumb and found to have AJCC V. 7 stage IIIb
melanoma . -
pubmed
Responsiveness to Change of the Montreal Cognitive Assessment , Mini - Mental State Examination , and SCOPA - Cog in Non - Demented
Patients with
Parkinson ' s Disease . -
pubmed
BACKGROUND : Clinical monitoring of
patients with
Parkinson ' s disease (
PD ) for
cognitive decline is an important element of care . -
pubmed
METHODS : PD
patients without
dementia were enrolled at 6 North American
movement disorders centers between 2008 and 2011 . -
pubmed
CONCLUSION : Using neuropsychological testing as a gold standard comparator , the performance of the MoCA , MMSE , and SCOPA - Cog for detecting decline in non - demented
PD patients over a 1 - year interval is poor . -
pubmed
METHODS : A prospective study that includes
patients aged & gt;= 69 years that live at home before the
fracture , admitted from June 1st , 2010 , to May 31st , 2013 . -
pubmed
Correction : paediatric goal management training in
patients with
acquired brain injury : study protocol for a randomised controlled trial . -
pubmed
Phacoemulsification , visco - goniosynechialysis , and goniotomy in
patients with primary angle - closure
glaucoma : A comparative study . -
pubmed
OBJECTIVE : The aim of this study was to evaluate the effects of goniotomy on
patients with primary angle - closure
glaucoma who underwent " phacoemulsification and visco - goniosynechialysis . " -
pubmed
MATERIALS AND METHODS : This prospective randomized clinical trial was carried out on 63 eyes of 61
patients ( 48 - 85 years ) with primary angle - closure
glaucoma who were enrolled . -
pubmed
None of the
patients developed a full
refeeding syndrome . -
pubmed
As an alternative , the
cat is an unfamiliar but powerful model of
human asthma . -
pubmed
Furthermore , induced pluripotent stem cell ( iPSC)-derived neurons of
patient with
Down syndrome showed absence of LTP or LTD . -
pubmed
We observed that the growth of xenograft
tumors derived from
NSCLC cell lines in
nude mice was significantly inhibited by combination therapy . -
pubmed
For the
stroke mouse model ,
FCCP ( 1 mg / kg , i.p ) or vehicle was administered followed by 1 - hour transient
middle cerebral artery occlusion (
tMCAO ) . -
pubmed
The
mice pretreated with
FCCP had a significantly increased
infarct volume within the cortex , striatum , and total hemisphere . -
pubmed
Mice receiving
FCCP had a significantly increased
neurological deficit score compared to the vehicle . -
pubmed
Uncoupling the electron transport chain with
FCCP prior to tMCAO exacerbated
stroke infarction in
mice . -
pubmed
RESULTS : We included 682
cysts for 621
patients , the imaging performed was relevant in 55 % of cases , not relevant but justified in 25 % and irrelevant in 20 % . -
pubmed
Here , we evaluated the prognostic value of HRQoL using the Functional Assessment of Cancer Therapy - General ( FACT - G ) in advanced
non - small - cell lung cancer (
NSCLC )
patients treated with Korean medicine . -
pubmed
Methods : A retrospective review of medical records and FACT - G scores of
patients with advanced
NSCLC who received treatment with Korean medicine was conducted . -
pubmed
Results : Of the 165 enrolled
patients , 115 ( 70 % ) had extrathoracic
metastasis and 139 ( 84 % ) had undergone prior anticancer treatment . -
pubmed
After adjusting for age , sex , smoking history , ECOG - PS , histological type , and presence of extrathoracic
metastasis , a high FACT - G total score ( hazard ratio ( HR ): 0.99 , p=0.032 ) and high PWB score ( HR : 0.94 , p < 0.001 ) were associated with prolonged survival as independent prognostic factors in
patients with advanced
NSCLC . -
pubmed
Conclusion : The FACT - G total score and PWB score as HRQoL measurements were significant prognostic factors for survival in advanced
NSCLC patients treated with Korean medicine . -
pubmed
This finding implies that the FACT - G can be used in clinical practice as a predictor of survival in
patients with advanced
NSCLC . -
pubmed
A new aggressive xenograft model of
human colon cancer using
cancer - associated fibroblasts . -
pubmed
Almost half of the
patients present
recurrence within 5 years after the treatment of the primary
tumor , the majority , with metastasis . -
pubmed
The objective of this study was to identify an adequate
animal model to study metastatic
colon cancer and the application of new treatments . -
pubmed
Methods :
Human CAFs and
normal fibroblasts ( NF ) for transplant and culture were obtained from surgical fresh samples of
patients with
adenocarcinoma of sigmoid colon . -
pubmed
Conclusion : Our experiments demonstrate that cultured CAFs have a higher growth than
NF and that when
human CAFs are associated to
human tumor cells , larger
tumors with
liver and lung metastases are generated than if only
colon cancer cells with / without NF are transplanted . -
pubmed
Here , we investigated the potential of
ribavirin as a targeted anti -
cancer agent in five
human NPC cell lines . -
pubmed
A training cohort used for diagnostic modelling included 30
patients with
STEMI , 38 with
stable angina (
SA ) and 30 matched - controls . -
pubmed
Serum EV concentration from
STEMI patients was increased as compared to controls and
SA . -
pubmed
EV biomarkers hold great potential as early markers for the management of
patients with
MI . -
pubmed
Individuals with
amnestic mild cognitive impairment (
aMCI ) have a high risk of developing
Alzheimer ' s disease . -
pubmed
Although repetitive transcranial magnetic stimulation ( rTMS ) is considered a potentially effective treatment for
cognitive impairment in
patients with
aMCI , the neuroimaging mechanisms are poorly understood . -
pubmed
Therefore , we performed a double - blind randomized sham - controlled trial in which rTMS was applied to the left dorsolateral prefrontal cortex of
aMCI patients recruited from a community near the Third Hospital Affiliated to Sun Yat - sen University , China . -
pubmed
Twenty - four
patients with
aMCI were randomly assigned to receive true rTMS ( treatment group , n = 12 , 6
men and 6
women ; age 65.08 + - 4.89 years ) or sham stimulation ( sham group , n = 12 , 5
men and 7
women ; age 64.67 + - 4.77 years ) . -
pubmed
These findings suggest that high - frequency rTMS can effectively improve cognitive function in
aMCI patients and alter spontaneous brain activity in cognitive - related brain areas . -
pubmed
The effect of fermented Huyou juice on intestinal microbiota in a high - fat diet - induced
obesity mouse model . -
pubmed
This study mainly discussed the effect of fermented Huyou juice ( FHJ ) on modulating the intestinal microbiota of
human , and anti -
obesity mechanisms . -
pubmed
Through the way of metagenomics , the effect of FHJ on gut flora has been summarized with a
mice model of
obesity induced by
human flora - associated ( HFA ) high - fat diet . -
pubmed
A Re - evaluation of the Taxonomy and Classification of the Type III Secretion System in a Pathogenic Bacterium Causing
Soft Rot Disease of
Pleurotus eryngii . -
pubmed
Pantoea beijingensis , a gram - negative pathogenic bacterium , causes
soft rot disease in the fungus
Pleurotus eryngii in China . -
pubmed
RESULTS : The mean age of first symptoms with
Usher syndrome type IIa and nonsyndromic
RP patients was 13.7 versus 29.8 years ( ocular phenotypes , p < 0.001 ) ; 17.7 versus 29.9 years (
nyctalopia , p < 0.001 ) ; 44.7 versus 54.8 years (
low vision based on VF , p < 0.001 ) ; 41.7 versus 54.7 years (
low vision based on VA , p < 0.001 ) ; and 46.0 versus 56.7 years ( legal
blindness based on
VF , p < 0.001 ) . -
pubmed
The
human gut - lung microbiota interplay provides a framework for therapies in the treatment and management of several
pulmonary diseases and
infections . -
pubmed
were found in 38 % ( 319/829 ) of
insulin - dependent diabetic patients , in 5 % ( 6/112 ) of
insulin - independent diabetics , and in 1.7 % ( 3/177 ) of
non - diabetic subjects . -
pubmed
in
patients with either
diabetes of recent onset or longstanding disease . -
pubmed
Reactivity of normotensive and spontaneously
hypertensive rats ( SHR ) to some antihypertensive agents after acute and chronic treatment . -
pubmed
Hypotensive action of some antihypertensive agents was studied on normotensive and spontaneously
hypertensive rats in acute and chronic treatment . -
pubmed
The reactivity of normotensive
rats was much more weaker than in
rats with spontaneous
hypertension (
SHR ) . -
pubmed
Three of the four
patients had a significant decrease in visual acuity as the result of a
retinopathy , primarily affecting the region about the macula accompanied by
macular edema . -
pubmed
Isolated , perfused , and ventilated
rat lungs were challenged by
paraquat ( 0.01 M ) in the presence of 2.5 mM
Ca2 + , 2.5 mM
Ca2 + with
trifluoperazine ( 100 microM ) , 0.025 mM
Ca2 + , or 0.025 mM
Ca2 + with
sodium metavanadate ( 10 microM ) to establish the effect of varying
calcium concentration or
calcium - dependent enzyme activities on
injury induced by
paraquat . -
pubmed
These findings are discussed in relationship to some current and future uses of selectively bred
animal strains and DD for studying the effects of
alcohol . -
pubmed
The primary role of imaging procedures in the preoperative staging of
patients with
bronchogenic carcinoma is to determine the need for further prethoracotomy assessment . -
pubmed
Calcium infusion induced
carcinoid symptoms in only two of six
patients , which were associated with elevated
5 - HT levels ( whereas elevated SP levels were seen in only one
patient ) . -
pubmed
It appears that
PG testing is superior to
calcium infusion as a provocative test in
patients with the
carcinoid syndrome . -
pubmed
Microvesicular
steatosis of the liver was observed in some
mice after 0.75 mmol / kg i.p . -
pubmed
Microvesicular
steatosis , however , requires very large doses in
mice ( 0.75 mmol / kg i.p . -
pubmed
The sera were titrated for complement fixing antibodies against
cytomegalovirus ( Ad169
strain ) . -
pubmed
Some
strains of
human immunodeficiency virus type 1 (
HIV-1 ) can infect primary monocytes and monocyte - derived macrophages in vitro . -
pubmed
Prevalence of
stephanofilariasis in young
Bos indicus cattle in northern Australia . -
pubmed
We studied B cell proliferation and differentiation in response to factors released by adherent monocytes in
patients with
systemic lupus erythematosus (
SLE ) . -
pubmed
Nonimmune
pigs passively immunized with monospecific
swine serum to capsule were protected from lethal
infection but not from development of
hemorrhagic lung lesions , whereas
pigs passively immunized with
swine antiserum to live bacteria did not develop severe
respiratory lesions . -
pubmed
A case of
peripheral ameloblastoma in the mandibular gingiva of a 42 - year - old
man has been reported . -
pubmed
Alveolar hemorrhage along with
glomerulonephritis developed in a 31 - year - old black
man . -
pubmed
Application of an immunoprecipitation procedure to the study of
SV40 tumor antigen interaction with
mouse genomic DNA sequences . -
pubmed
[ Ultrastructure of capillary permeability in
human brain tumors . -
pubmed
Using our modification of the vein patch technique , we created 16
aneurysms in the common carotid arteries of
dogs . -
pubmed
One
human facial
artery aneurysm was similarly treated . -
pubmed
Because no experimental
aneurysm models are yet physiological , our results must be applied with caution to
human intracranial aneurysms . -
pubmed
Intravenous injection of the extracts into healthy
chickens showed that lethality of infected tissue extracts was higher than control extracts and was independent of the site of
infection within the intestine . -
pubmed
[ Changes in the estrus cycle in the estrus cycle of
rats with
alloxan diabetes ] . -
pubmed
The course of an experimental
liver fluke infection in the
pig . -
pubmed
Some structural aspects of
carious lesions in
human dentin . -
pubmed
[ Time relationships of radiation - induced
chromosome aberrations in
humans ] . -
pubmed
[
Coronary heart disease and
hypertension in older
workers of an industrial plant ] . -
pubmed
The results of the experiments allow the conclusion that native crude fibres , as long as they remain in the normal range between 3 and 7 % in the ration does not cause a
depression in the true digestibility of
nitrogen and the
amino acids in the feeding of fattening
pigs . -
pubmed
Immunoproliferative small intestinal disease in Basenji
dogs : morphologic observations . -
pubmed
Colestipol : a review of its pharmacological properties and therapeutic efficacy in
patients with
hypercholesterolaemia . -
pubmed
Thus , like
cholestyramine ,
colestipol is of benefit in
patients with
primary hypercholesterolaemia without associated
hypertriglyceridaemia (
type IIa hyperlipoproteinaemia ) . -
pubmed
[ Recovery from from
Listeria monocytogenes meningitis in an adult ] . -
pubmed
The authors describe a case of
meningitis by
Listeria monocytogenes from which the patient , an adult suffering from a
chronic lymphatic leukosis , recovered completely . -
pubmed
Two patients with
systemic lupus erythematosus developed
monarticular infectious arthritis , in which
Neisseria meningitidis was recovered from knee synovial fluid . -
pubmed
Two outbreaks of
sternal wound infection due to organisms of the
Mycobacterium fortuitum complex . -
pubmed
Two outbreaks of postoperative
wound infections due to organisms of the
Mycobacterium fortuitum complex (
Mycobacterium chelonei and
M. - pubmed
In one hospital , 19 of 80 patients who underwent cardiac surgery within a 10 - week period developed
sternal infection with
M. - pubmed
In the second hospital , four of nine patients who underwent cardiac surgery within a two - week period developed sternal incisional
infection with
M. - pubmed
Congenital tricuspidal insufficiency in two young beagle ( Cpb - DoBe67 )
dogs . -
pubmed
Spontaneous
peritonitis in a
patient with
cirrhosis of the liver and
ascites . -
pubmed
The
syndrome of spontaneous
peritonitis in
patients with
cirrhosis of the liver and
ascites is discussed on the basis of a case history , with special reference to the diagnosis , pathogenesis and treatment of this
syndrome . -
pubmed
Morphological analysis of imprint histology and cytology was performed in 7
patients with
yolk sac tumor (
YST ) . -
pubmed
Polysaccharide -
iron - regulated cell surface protein conjugate vaccine : its role in protection against
Klebsiella pneumoniae - induced
lobar pneumonia . -
pubmed
Klebsiella pneumoniae has become an important cause of both community - acquired and
nosocomial infections . -
pubmed
It was found to be immunogenic and the protection afforded by the conjugate against the challenge
strain was observed in a
rat lobar pneumonia model . -
pubmed
A four - drug combination chemotherapy with
cisplatin ,
mitomycin ,
vindesine and
5 fluorouracile : a regimen associated with major
toxicity in
patients with advanced
non - small cell lung cancer . -
pubmed
The purpose of this study was to determine the activity of a 4 - drug combination chemotherapy :
cisplatin ,
mitomycin C ,
vindesine and
5 - fluorouracil (
5 - FU ) in
patients with advanced
non - small cell lung cancer (
NSCLC ) . -
pubmed
Among 182 eligible
patients , 75 % had received no prior therapy ; 41 % had locoregional disease and 59 % metastatic
disease ; 41 % lost more than 5 % of their pretherapy
body weight . -
pubmed
Patients with locoregional disease had a significantly better response rate than those with
metastases ( 44 % vs 27 % ) . -
pubmed
A 33 - year - old right - handed
woman had intractable simple and complex partial
seizures (
SPS ,
CPS ) that began with global
aphasia . -
pubmed
Eight - seven
acetabular fractures in eighty - seven
patients underwent open reduction and internal fixation at Vanderbilt University Hospital from 1984 to 1989 . -
pubmed
We evaluate the effects of chronic
hypoxia on the metabolic phenotype of the muscle fiber types of
humans . -
pubmed
Chronic
hypoxia appears to produce a shift from oxidative to glycolytic metabolism in those fibers which are typically the most aerobic in
human muscle . -
pubmed
Healing of
foot ulcers in immunosuppressed renal transplant
patients . -
pubmed
Sixteen renal transplant
patients were retrospectively studied to determine the time foot
ulcerations healed . -
pubmed
Six
men ( average age , 42 ) underwent evaluation for
idiopathic osteoporosis . -
pubmed
The results suggest that
idiopathic osteoporosis in these
men is associated with increased
parathyroid hormone secretion as assessed by increased renal
cyclic adenosine monophosphate and high skeletal remodeling activity . -
pubmed
In infants with gestational age & lt ; 29 weeks the risk for
death in
C. - pubmed
The outbreak was most likely a result of
cross - infection because
C. - pubmed
Unenhanced helical CT in
patients with
acute flank pain and
renal infarction : the need for contrast material in selected cases . -
pubmed
MATERIALS ,
PATIENTS AND METHODS : The incidence , clinical course and location of
PBS in 97 operated
women were studied for a 15 - year period . -
pubmed
RESULTS : The incidence of
PBS was 29
patients out of the 97 total . -
pubmed
The
syndrome was present for more than 48 months in eleven of these
patients . -
pubmed
In most cases the location of "
phantom sensations " was the nipple ( 15 cases ) and the entire breast in five
patients . -
pubmed
In only three
patients was phantom
breast pain (
PBP ) reported whereas some discomfort was reported by the other
patients . -
pubmed
A comparison of tests to determine acuity deficits in
children with
amblyopia . -
pubmed
Visual function was measured using pattern visual evoked potentials ( VEPs ) , the Cardiff test , and the Bailey - Lovie Chart in 21 visually normal
children and 12
children with
amblyopia . -
pubmed
The Cardiff test identified five of the 12
children who were classified as
amblyopic by the Bailey - Lovie test . -
pubmed
Interocular VEP latency differences identified eight of the 12
children with
amblyopia ; interocular VEP amplitudes correctly identified nine . -
pubmed
BACKGROUND : Treatment of
patients with
malignant pleural effusions is mostly palliative . -
pubmed
METHODS : Sixty
patients with massive
malignant pleural effusions were divided in 3 equal groups in a simple randomized manner . -
pubmed
Patients with
bone metastasis were evaluated repeatedly by bone scan at intervals of 3 - 6 months . -
pubmed
Emergency tracheostomy often is needed in
patients who have primary
subglottic tumors or
tumors than invade the subglottis . -
pubmed
Aggressive local treatment is recommended in
patients with
subglottic lesions or
subglottic tumor extension to prevent
SR . -
pubmed
We reviewed the histopathological diagnosis of
human cytomegalovirus (
HCMV ) and the pathology of
HCMV infection in immunocompromised hosts . -
pubmed
Peripheral tears were made unilaterally in the medial menisci of seven
goats in Group I and repaired with nonabsorbable suture . -
pubmed
Correlation between humoral responses to
human immunodeficiency virus type 1 envelope and
disease progression in early - stage
infection . -
pubmed
Rupture and growth of
adrenal myelolipoma in two
patients . -
pubmed
SAMPLE POPULATION : Skin of
porcine cadavers . -
pubmed
This study reviews , over a 5 - year period , the records of 70 consecutive
patients with prosthetic
knee infection and evaluates outcomes as a function of a staging system for
prosthetic joint infection . -
pubmed
Many of
hypertensive individuals have
glucose intolerance and
dyslipidemia , and
insulin resistance is common disorder on the basis of these diseases . -
pubmed
Although generally thought of as a T cell - driven
autoimmune disease , recent studies in
experimental allergic encephalomyelitis (
EAE ) , the
animal model of
multiple sclerosis , suggest a significant role for innate immune mechanisms . -
pubmed
Rat or
human hepatoma cells in
HEMA - MMA microcapsules lost viability within a week after implantation into an omental pouch in
Wistar rats . -
pubmed
Bacillus subtilis Bios11
strain was previously isolated and identified . -
pubmed
When compared with lean
rats , the rate of
triglyceride synthesis in red muscle was 158 % higher in
obese rats , and the rate of
palmitate incorporation into
diglycerides in white muscle was 93 % higher in
obese rats . -
pubmed
Pre- and postperfusion muscle
triglyceride levels were higher in both red and white muscles of the
obese rats . -
pubmed
These results show that increased
FA uptake and altered
FA disposal to storage may contribute to the development of
muscle insulin resistance in
obese Zucker
rats . -
pubmed
We report a case of a 22 - year - old
woman with
relapsing polychondritis (
RP)--a rare and little known systemic
autoimmune disease characterised by
episodic inflammation of cartilaginous structures ( ear , nose , bronchi , trachea , larynx , ribs , cardiovascular system ) . -
pubmed
The presence of anterior
knee pain referable to the patella was 7.1 % ( five
patients , six knees ) in Group A ( one patient with two knees had severe
anterior knee pain ) and 9 % ( 13 knees in 13
patients ) in Group B. -
pubmed
The population consisted of 10 consecutive
patients with
atrial tachycardia resistant to more than 2 drugs , 7 female , mean age 45 + /- 12 years . -
pubmed
The histories of thirteen
patients who presented with
seizures secondary to benign intraaxial lesions treated by craniotomy and resection within the iMRI unit at our institution were reviewed . -
pubmed
At follow - up , five
patients had no
seizures , 5 had rare
seizures and the remaining 3 had worthwhile improvement in
seizure frequency . -
pubmed
METHODS : We studied 4,347
patients ( mean age , 61 + /- 12 years ; 2,230
men ) with known or suspected
coronary artery disease by symptom - limited exercise echocardiography . -
pubmed
Their hemagglutination capability with
human erythrocytes was also tested , which was positive only for a few
strains . -
pubmed
Between August 1997 and October 1998 , 12 consecutive adult
patients ( & gt;18 years ) with high - risk
acute myeloid leukemia (
AML ) ( four
patients in first early
relapse , seven
patients with
secondary AML , and one
patient with de novo
AML concomitant to a
lymphoproliferative disorder ) were enrolled to receive a single course of
HY ( 100 mg / kg per day ) until
bone marrow aplasia or for a maximum of 30 days . -
pubmed
This study has demonstrated the safety and efficacy of
HHY in inducing CR in
AML patients with unfavorable prognosis . -
pubmed
CONCLUSION : A complementary psychological treatment of
patients suffering from
CIU seems necessary , because of the high frequency of psychological symptoms . -
pubmed
[ Innervation of the
human gallbladder ; its changes in
cholelithiasis ] . -
pubmed
HOST - AGENT INTERACTION IN EXPERIMENTAL
TUBERCULOSIS IN
GUINEA PIGS , WITH SPECIAL REFERENCE TO THE EFFECTS OF BCG VACCINATION . -
pubmed
The influence of unilateral nephrectomy on the development of
stilboestrol - induced
renal tumours in the male
hamster . -
pubmed
The effects of radiosurgery for metastatic
brain tumors have been thought to be superior to fractionated radiotherapy due to high response and control rates , and
patients showed improved quality of life although no prolongation of the life span was obtained . -
pubmed
Community - based rehabilitation improves function of
patients with
traumatic brain injury . -
pubmed
Myocardial , hepatic and renal damage resulting from
para - aminobenzoic acid therapy ; observations in
human cases and experimental animals . -
pubmed
Two hundred and sixty
patients with
T1DM with and without
diabetic microvascular complications , and 104 normal controls were recruited for this study . -
pubmed
Feline immunodeficiency virus vectors for efficient transduction of primary
human synoviocytes : application to an original model of
rheumatoid arthritis . -
pubmed
Because of the safety concerns raised by
HIV vectors , we developed a gene delivery system derived from the ungulate lentivirus
feline immunodeficiency virus (
FIV ) . -
pubmed
A most recent large trial with
Ginkgo biloba clearly showed that this drug does not prevent
AMS in a low - risk setting in which
acetazolamide in a low dose of 2 x 125 mg was effective . -
pubmed
Serological responses from
osteoarthritis (
OA )
patients and normal
individuals to soluble proteins extracted from allografts were assessed using Western blotting and ELISA techniques . -
pubmed
Antibodies were present in
patients without the use of bone allografts , indicating that
OA patients develop antibodies to bone soluble proteins . -
pubmed
Soon to be published work from our laboratory has shown that ingestion of
Perna canaliculus prevents the development of
autoimmune diseases such as
Systemic Lupus Erythematosus and
rheumatoid arthritis in laboratory animals . -
pubmed
Therefore , we xenografted subcutaneously into
nude mice seven
human colonic
tumours ( from stages B1 to D ) that showed
chromosome instability and transplanted them sequentially for up to 14 passages . -
pubmed
The observation that some loci showed partial allelic imbalance in the initial
tumour but loss of heterozygosity after the first passage in
nude mice when all the
normal cells were lost may allow identification of interesting genetic defects that could be involved in
tumour expansion . -
pubmed
A higher number of steps were climbed and a shorter time was taken to revert to the basal
pulse rate ( recovery time ) by non - anemic
girls compared to
anemic girls ( P & lt ; 0.001 ) . -
pubmed
METHODS : Five
patients with
MEWDS ( selected based on angiographic manifestations of the disorder ) were examined using slitlamp biomicroscopy and studied using
fluorescein angiography and
indocyanine green angiography . -
pubmed
RESULTS : All 5
patients exhibited the newly recognized angiographic features termed dots and
spots , which varied in size and location in the fundus . -
pubmed
All
patients exhibited other characteristics typical of
MEWDS , including field loss and foveal granularity . -
pubmed
METHODS : Sixty - two
patients with low rectal
cancer underwent low anterior resection and total mesorectal excision ( TME ) . -
pubmed
Five
patients with microscopic
tumor nodule spread in the CRM observed in the study suggested that microscopic
metastases exist in pelvic lateral areas and in the mesorectum simultaneously , indicating the significance of preoperative and/or postoperative radiochemotherapy . -
pubmed
Microvessel density in the placental bed among
preeclampsia patients . -
pubmed
CONTEXT AND OBJECTIVE : Morphological changes in the spiral arteries of the placental bed have been studied in
patients with
preeclampsia , one of the largest causes of maternal and perinatal morbidity and mortality . -
pubmed
RESULTS : Biopsies containing spiral arteries were obtained from 34
hypertensive pregnant
women with
proteinuria , and 26 normotensive pregnant
women . -
pubmed
These
alpha - galacto - oligosaccharides ( alpha - GOS ) , which are found in large quantities in
vegetables , such as
soy , can cause
gastrointestinal disorders in sensitive
individuals because monogastric
animals ( including
humans ) do not posses
alpha - Gal in the gut . -
pubmed
PURPOSE : Clearance of mucus from airways is the cornerstone of therapy for
lung disease in
patients with
cystic fibrosis (
CF ) . -
pubmed
The Frequencer induced airway clearance in
patients with
CF that was equivalent to that of CCPT . -
pubmed
CONCLUSIONS : These results indicate the Frequencer is safe and as effective as CCPT in inducing airway clearance in
patients with
CF . -
pubmed
The effect of
melatonin on
endotoxemia - induced intestinal apoptosis and oxidative stress in infant
rats . -
pubmed
The
animals were randomized into three experimental groups : ( 1 ) controls ; ( 2 )
endotoxemia ; ( 3 )
endotoxemia treated with
melatonin ( 10mg / kg ) . -
pubmed
The administration of
melatonin into endotoxemic
rats prevented the increase in the TBARS levels , and increased the activities of antioxidant enzymes and attenuated apoptotic cell
death in both intestinal epithelium and lamina propria . -
pubmed
CONCLUSIONS :
Melatonin diminished the intestinal oxidative stress and apoptotic damage induced by
endotoxemia in infant
rats . -
pubmed
Despite the large resource of transgenic and knockout
mice harboring mutations relevant to
skin disorders , few organotypic
mouse skin models are available . -
pubmed
Limbic structures are prone to age - related impairments in proteasome activity and neuronal ubiquitinated inclusions in SAMP10
mouse : a model of
cerebral degeneration . -
pubmed
Invasive
fungal infection in severely immunosuppressed patients with
acute myelogenous leukemia (
AML ) remains a serious challenge because ( a ) of the higher rates of non - drug susceptible
fungal sinopulmonary disease ; ( b ) despite advances in diagnostic fungal assays , the correct identification of causative organism(s ) is difficult , and antifungal drug susceptibility data are seldom available during clinical decision making ; and ( c ) the increasing frequencies of
zygomycosis ,
scedosporiosis , and highly virulent
Candida tropicalis infection have undermined the gains attributed to effective anti -
Aspergillus drug therapy . -
pubmed
Sixty percent of the
patients who presented with
leukocoria had
congenital cataract ( 18 % unilateral and 42 % bilateral ) . -
pubmed
Leukocoria in
children demands immediate attention because a significant number of children have pathology that either threatens life or causes permanent
visual disability . -
pubmed
We present the case of a 28 - year - old
woman at 25 weeks of gestation diagnosed with Stage 1B
cervical cancer . -
pubmed
Double
infection of
tobacco protoplasts with
brome mosaic virus and
cowpea chlorotic mottle virus . -
pubmed
Mixed infections of
tobacco protoplasts with
Cowpea chlorotic mottle virus (
CCMV ) and
brome mosaic virus (
BMV ) have been studied . -
pubmed
,
BMV dominated in
mixed infections and prevented synthesis of infectious
CCMV . -
pubmed
Healthy protoplasts could be infected after several hours in culture but the susceptibility to
infection decreased with time in culture ; the decrease was much faster with
BMV than with
CCMV , probably because the difference in electrical charge of the two viruses affects the method of entry into the protoplasts . -
pubmed
If inoculation with the second virus was delayed there was an increasing resistance to
superinfection ( interference or cross - protection ) so that when the delay between inoculations was more than 8 hr
BMV was no longer able to infect protoplasts previously infected with
CCMV and vice versa . -
pubmed
Attempts to rescue a temperature - sensitive
strain of
CCMV with
BMV under restrictive conditions ( 35 degrees ) were unsuccessful ; dominance by
BMV prevented synthesis of infectious
CCMV RNA . -
pubmed
The quality of the starting material is highly guaranteed for blood derivatives due to the individual screening for specific markers ( antigens , genome , antibodies ) for major blood borne viruses such as
hepatitis B and C viruses (
HBV ,
HCV ) and
human immunodeficiency virus (
HIV ) . -
pubmed
BACKGROUND : This study examines the clinical , echocardiographic , surgical , and pathologic features of
patients who had heart valve operations for combined
congenital bicuspid aortic valve and
mitral regurgitation due to
degenerative disease of the mitral valve . -
pubmed
METHODS : A retrospective review of 1595
patients who had procedures for
mitral regurgitation due to
degenerative disease of the mitral valve and 1820
patients who had procedures for
congenital bicuspid aortic valve disclosed 29
patients who had combined diseases . -
pubmed
Mitral regurgitation in 21 of 29
patients was caused by
prolapse of the anterior leaflet , which was exceptionally large ( mean height , 36.5 + /- 6.6 mm ) . -
pubmed
The
bicuspid aortic valve was incompetent in 19 of 21 , and the aortic annulus exceeded 30 mm in 20 of 21
patients . -
pubmed
CONCLUSIONS :
Patients with combined
mitral regurgitation due to
myxomatous degeneration and
bicuspid aortic valve disease who require operations often have a large , prolapsing anterior leaflet of the mitral valve and dilated aortic annulus with
aortic insufficiency due to
cusp prolapse . -
pubmed
Commentary : Below - the - ankle subintimal angioplasty : how far can we push this application for lower limb preservation in
diabetic patients ? -
pubmed
PURPOSE :
Patients with advanced
gastric or gastroesophageal adenocarcinoma need more efficacious and safer treatments than established
today . -
pubmed
One thousand fifty - three
patients were stratified ( center , number of metastatic sites , prior adjuvant therapy , and measurable
cancer ) and randomly assigned . -
pubmed
The primary end point was superiority in overall survival ( OS ) from
cisplatin / S-1 compared with
cisplatin / infusional
fluorouracil in
patients with advanced , untreated gastric , or
gastroesophageal adenocarcinoma . -
pubmed
CONCLUSION :
Cisplatin /
S-1 did not prolong OS of
patients with advanced
gastric or gastroesophageal adenocarcinoma compared with
cisplatin / infusional
fluorouracil , but it did result in a significantly improved safety profile . -
pubmed
The offspring of an
individual with any of the subtypes of
CMT1 have a 50 % chance of inheriting the altered gene . -
pubmed
OBJECTIVES : To investigate the impact of different definitions on the frequency of
benign multiple sclerosis (
MS ) in
patients with a long follow - up , and to study the presence of non - motor symptoms and employment across the definitions . -
pubmed
These results suggest that maintaining
genome stability by heterochromatin formation and correct chromosomal packaging is essential for normal cellular functions and for survival of
animals under genotoxic stress . -
pubmed
The effect of
succinate on
pentobarbital toxicity and
narcosis in the
cat . -
pubmed
Over the last two decades multiple studies have demonstrated an increased incidence of additional
malignancies in
patients with
intraductal papillary mucinous neoplasms (
IPMNs ) . -
pubmed
CASE SUMMARY : we report a 25 - year - old
woman presenting with sudden onset of
vertigo ,
hoarseness ,
dysphagia ,
right facial numbness , and proximal
quadriparesis . -
pubmed
INTRODUCTION :
Vitamin K antagonists ( VKAs ) are the main therapeutic agents used to prevent embolic events in
patients with
atrial fibrillation (
AF ) . -
pubmed
Hippoglossus hippoglossus with the
gaping - jaw malformation , common in intensively cultured individuals of this species , were examined histologically . -
pubmed
BACKGROUND AND OBJECTIVE : To report on a new surgical technique for
neovascular glaucoma (
NVG ) in
patients with proliferative
diabetic retinopathy or
retinal vein occlusion . -
pubmed
To maintain an IOP of less than 21 mm Hg without anti -
glaucoma medications , surgical revisions of the filtration site are necessary in at least 50 % of
patients . -
pubmed
We have previously shown that
human sleep - wake stage distributions exhibit multi - exponential dynamics , which are fragmented by
obstructive sleep apnea (
OSA ) , suggesting that Markov models may be a useful method to quantify architecture in health and disease . -
pubmed
BACKGROUND : Two vaccines against
human papillomavirus (
HPV ) , a necessary cause of
cervical cancer , are currently licensed and recommended for routine administration in the U.S. to girls in a three - dose series . -
pubmed
We did not find a higher morbidity or mortality in
patients with a more severe
liver damage measured by the CASH score . -
pubmed
We report the frequency and effectiveness of
patient - initiated epilation and its relationship to
corneal opacity . -
pubmed
The presence of Plus disease was identified by the non - ophthalmologist and results compared to the clinical examination by a pediatric
ophthalmologist experienced in
ROP detection and treatment . -
pubmed
Hepatoportal sclerosis in childhood : some presenting with
cholestatic features ( a re - evaluation of 12
children ) . -
pubmed
Between 1999 and 2009 , 12
children diagnosed with
HPS were retrospectively evaluated . -
pubmed
Histopathologically , all
patients had
hepatoportal sclerosis / intimal fibrous thickening of portal vein and periportal
fibrosis , acinar transformation , and regenerative nodules not surrounded by fibrous septae . -
pubmed
Eight
patients had
vascular aberrations , 7 had ductular reaction , 1 showed mild
cholangitis , and 1 had canalicular bile pigment . -
pubmed
Cytotoxicity tests were implemented on
MCF-7 Human breast cancer cell line for the investigation of drug and
polymer toxicity . -
pubmed
Effects of bone marrow mesenchymal stem cells in a
rat model of
myocardial infarction . -
pubmed
METHODS :
MI was induced in 21
Sprague - Dawley rats by ligation of the left anterior descending artery . -
pubmed
CONCLUSIONS : MSCs can differentiate into beating cardiomyocytes in a
rat model of
MI and improve myocardial function . -
pubmed
Bone
metastasis is a common incurable complication of
breast cancer affecting around 70 % of
patients with advanced disease . -
pubmed
In order to improve outcomes for these
patients , the cellular and molecular mechanisms underlying bone
metastasis need to be established . -
pubmed
Tumour growth in bone was initiated by intra - cardiac inoculation of
MDA - MB-231 - GFP breast cancer cells in immunocompromised
mice . -
pubmed
CONCLUSIONS : Pacific people in New Zealand have a disproportionate
cancer burden related to
infectious diseases such as
HPV and
Hepatitis B. However , with escalating evidence for causal associations between
diabetes ,
obesity , and physical inactivity with various
cancers , the challenge will be to prevent these
cancers from rising in Pacific people who have the highest rates of these conditions in New Zealand . -
pubmed
Disparities for
tobacco - related
cancers support
tobacco consumption as another important cause of
cancer incidence disparity . -
pubmed
METHODS :
Hypertrophic scar samples were collected from 42
patients with
hypertrophic scar for 1 - 20 years ( mean , 4.5 years ) , including 15
males and 27
females with an average age of 32.6 years ( range , 16 - 50 years ) . -
pubmed
Scaffold - free adipose - derived stem cells ( ASCs ) improve experimentally induced
osteoarthritis in
rabbits . -
pubmed
METHODS :
OA was induced in adult
white New Zealand rabbits by unilateral anterior cruciate ligament transection ( ACLT ) ; the contralateral knee was considered the sham - operated group . -
pubmed
This case report presents a young 30 - year old male
patient with
type 1 diabetes mellitus , who was treated for
hypoglycemia and a general bad feeling . -
pubmed
Reinforcing properties of
Pramipexole in normal and
parkinsonian rats . -
pubmed
While
parkinsonian were slower than sham
rats in acquiring self - administration behavior , they later reached the same level of intake . -
pubmed
A neonatal model of
intravenous Staphylococcus epidermidis infection in
mice & lt;24 h old enables characterization of early innate immune responses . -
pubmed
Staphylococcus epidermidis (
SE ) causes late onset
sepsis and significant morbidity in catheterized preterm newborns . -
pubmed
Current
murine models of neonatal
bacterial infection employ intraperitoneal or subcutaneous routes at several days of age , and may , therefore , not accurately reflect distinct features of innate immune responses to
bacteremia . -
pubmed
Long - term changes of diffusion tensor imaging and behavioural status after acupuncture treatment in
rats with transient focal
cerebral ischaemia . -
pubmed
A study was undertaken to assess its effects in
rats with transient
middle cerebral artery occlusion (
tMCAO ) and discuss its mechanisms . -
pubmed
CONCLUSIONS : The acupuncture points applied were effective , and improving neuronal regeneration may have a role in the mechanism of acupuncture treatment of
post - stroke paralysis of the limbs in
rats . -
pubmed
CONCLUSIONS : There was no significant difference in the presence of
NAFLD between AI
patients and controls . -
pubmed
Effect of different levels of supplemental
yeast on
body weight , thyroid hormone metabolism and lipid profile of
broiler chickens . -
pubmed
The present study examined the effect of supplemental
yeast probiotic preparations on
body weight , thyroid hormone metabolism and serum lipid profile in
broilers . -
pubmed
Chickens fed 2.0 % probiotic had a significantly ( P<0.05 ) higher
body weight when compared with the control group . -
pubmed
In conclusion , supplementing broiler feeds with a
yeast probiotic increased
body weight , enhanced thyroid hormone metabolism , and decreased
cholesterol and lipoproteins in
broiler chickens . -
pubmed
Titanium oxide nanoparticle instillation induces
inflammation and inhibits lung development in
mice . -
pubmed
Titanium oxide (
TiO ( 2 ) ) nanoparticles , which are commonly used in cosmetics , sunscreens , paints , and food , have been shown to induce
emphysema and lung inflammation in adult
mice . -
pubmed
We hypothesized that exposure of newborn
mice to
TiO ( 2 ) would induce
lung inflammation and inhibit lung development . -
pubmed
METHODS : We used a validated atlas registration to locate and stimulate through electrode contacts in D - STN and V - STN regions of 37
people with
Parkinson ' s disease . -
pubmed
RESULTS : Internalizing and externalizing problems were significantly represented among children with
headaches compared to the control group , respectively 63 % and 27 % , without significant differences between
migraine and
tension - type headache children . -
pubmed
These in vitro results suggest
CGMP , LB , EPS and WB as good candidates to be included in
piglet 's diet with supported functional activity against
colibacillosis . -
pubmed
In this study ,
canine AD - MSCs ( cAD - MSCs ) were individually isolated from five
dogs and subjected to proliferative culture with seven sub - passages . -
pubmed
OBJECTIVE : The aim of this study based on the records of the dermatology department of a tertiary referral hospital was to describe
patients treated for
allergic contact dermatitis induced by
nickel between 2000 and 2010 . -
pubmed
MATERIALS AND METHODS : From records of the
skin allergy section of the dermatology department we extracted and analyzed information for
patients who underwent patch testing with the standard series of the Spanish Contact
Dermatitis Research Group ( GEIDAC ) , which includes a patch with 5 %
nickel sulfate in petroleum jelly . -
pubmed
However , the
contact dermatitis could be attributed to
nickel in only 57 of the 824
patients ( 6.9 % ) who showed sensitization to
nickel . -
pubmed
This test is even useful for identifying the specific object responsible for a
patient 's
dermatitis . -
pubmed
CONCLUSIONS : Ustekinumab 45 and 90 mg treatments significantly inhibited radiographic progression of
joint damage in
patients with active
PsA. -
pubmed
HFD - fed CatE(-/- )
mice displayed reduced body
weight gain and defective development of white adipose tissue ( WAT ) and brown adipose tissue ( BAT ) , compared with HFD - fed wild - type
mice . -
pubmed
Moreover , fat - induced CatE(-/- )
mice showed abnormal lipid accumulation in non - adipose tissues characterized by
hepatomegaly , which is probably due to defective adipose tissue development . -
pubmed
Detailed pathological and biochemical analyses showed that
hepatomegaly was accompanied by
hepatic steatosis and
hypercholesterolemia in HFD - induced CatE(-/- )
mice . -
pubmed
The work is devoted to the description of neurological , vestibulometric and audiologic data obtained in the examination of 11
patients with
basilar type migraine . -
pubmed
We report a case of severe
hypertriglyceridemia - induced acute
pancreatitis in a 24 - year - old
woman caused by Estrostep , occurring nearly 10 years after she began using the drug . -
pubmed
We previously reported that synthetic
flavonoid dimers have potent antipromastigote and antiamastigote activity against
Leishmania donovani , the causative agent of
visceral leishmaniasis . -
pubmed
One of the
flavonoid dimers ( compound 39 ) has marked antipromastigote ( 50 % inhibitory concentrations [ IC50s ] , 0.19 to 0.69 muM ) and antiamastigote ( IC50s , 0.17 to 2.2 muM ) activities toward different species of
Leishmania that cause
cutaneous leishmaniasis , including
Leishmania amazonensis ,
Leishmania braziliensis ,
Leishmania tropica , and
Leishmania major . -
pubmed
In the
mouse model of
cutaneous leishmaniasis induced by subcutaneous inoculation of
L. - pubmed
amazonensis in
mouse footpads , intralesional administration of 2.5 mg / kg of
body weight of compound 39.HCl can reduce footpad thickness by 36 % , compared with that of controls values . -
pubmed
The authors performed repeated surgeries and small bowel resections on a
patient classified to stage number three on Bell scale due to
necrotizing enterocolitis . -
pubmed
In vivo imaging showed significantly higher fluorescence intensity in
OA knees compared to sham - operated ( control ) knees of the same
mice . -
pubmed
BACKGROUND AND OBJECTIVES : New therapeutic protocols for
patients with end - stage
Parkinson disease include a
carbidopa /
levodopa combination using continuous , modulated enteral administration via a portable pump . -
pubmed
RESULTS : Five
patients with end - stage
Parkinson disease were referred to our department after successful therapeutic testing with administration of
levodopa /
carbidopa via naso - jejunal tube . -
pubmed
PATIENTS AND METHODS : The study included 67
children with
chronic hepatitis B and 99 healthy controls . -
pubmed
The
hepatitis B patients were divided into immuntolerant , chronic inactive , and treatment groups according to their laboratory findings . -
pubmed
Loudness dependence of auditory evoked potentials ( LDAEP ) in clinical monitoring of suicidal
patients with
major depression in comparison with non - suicidal depressed
patients and healthy
volunteers : A follow - up - study . -
pubmed
Twenty
patients ( mean age 43.25 + - 10.85 , age range 20 - 61 , 11 male ) suffering from a major
depressive episode who had either acutely attempted suicide or who had suicidal plans and behavior , which are reflected by item 3 of Hamilton Depression Rating Scale & gt;= 3 (
suicidality ) , were included in the study . -
pubmed
Correction : Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during
Salmonella Typhimurium Colitis . -
pubmed
In
individuals with
histamine intolerance (
HIT ) ingestion of food with normal contents of
histamine causes
histamine - mediated symptoms . -
pubmed
A newly isolated
strain ,
CWD-67 , which exhibited high fibrinolytic activity , was screened from dumping soils enriched with poultry wastes . -
pubmed
The
strain was identified as
Bacillus tequilensis ( KF897935 ) by 16Sr RNA gene sequence analysis and biochemical characterization . -
pubmed
A new method for the detection of
cancer using 1 mul of
human serum , attenuated total reflection - Fourier transform infrared spectroscopy and pattern recognition algorithms is reported using a 433 patient dataset ( 3897 spectra ) . -
pubmed
METHODS : Data from 246
women with
phyllodes tumors of the breast treated in the Cancer Hospital , Chinese Academy of Medical Sciences between January 2002 and December 2012 , were collected and analyzed retrospectively . -
pubmed
56
patients had local
recurrence , 5
patients had distant
metastasis , while one case had both local
recurrence and distant
metastasis . -
pubmed
Type of primary surgery ,
fibroadenoma history and histological type are independent factors predicting the
disease - free survival of
patients with
phyllodes tumors of the breast . -
pubmed
The incidence of
infection ,
sepsis , and
multiple organ dysfunction syndrome (
MODS ) and the mortality of
patients were recorded during 2 months after
injury . -
pubmed
RESULTS : The 5 - year survival rate in our series was 45 % , and this percentage increased to 65 % when
patients with advanced stage
cancer ( stage IIIb or higher ) were excluded . -
pubmed
We achieved
cancer - free margins in 19
patients ( 60 % ) . -
pubmed
Cognitive reserve and cognitive performance of
patients with
focal frontal lesions . -
pubmed
This study reports the rates of RNFL thinning over the 6 x 6 mm2 RNFL thickness map and their application for indication of
visual field ( VF ) worsening in
patients with
glaucoma . -
pubmed
Objective : To investigate the association between the rates of RNFL thinning and the risk of VF worsening in
patients with
glaucoma . -
pubmed
Delayed diagnosis of shunt overdrainage following functional hemispherotomy and ventriculoperitoneal shunt placement in a
hemimegalencephaly patient . -
pubmed
The condition presents a diagnostic challenge particularly in
patients with
cognitive impairment and
developmental delays . -
pubmed
Here we present a 3 - year - old
boy with drug - resistant focal onset
seizures due to
hemimegalencephaly who previously underwent functional hemispherotomy followed by ventriculoperitoneal shunt placement for
postoperative hydrocephalus . -
pubmed
Vascular Anatomy Predicts the Risk of
Cerebral Ischemia in
Patients Randomized to Carotid Stenting Versus Endarterectomy . -
pubmed
Differential Recognition of
Mycobacterium tuberculosis - Specific Epitopes as a Function of
Tuberculosis Disease History . -
pubmed
OBJECTIVES : We hypothesized that the repertoire of
Mtb - derived epitopes recognized by T cells from individuals with latent
Mtb infection differs as a function of previous diagnosis of active
TB disease . -
pubmed
MEASUREMENTS AND MAIN RESULTS : We identified a set of " type 2 " T - cell epitopes that were recognized at 10 - fold - lower levels in
Mtb - infected individuals with a history of
TB disease less than 6 years ago than in those without previous
TB . -
pubmed
CONCLUSIONS : Preferential loss of T - cell reactivity to
Mtb epitopes that are homologous to bacteria in the microbiome in persons with previous
TB disease may reflect long - term effects of antibiotic TB treatment on the microbiome . -
pubmed
We evaluated the effectiveness of
Tc-99 m ECD SPECT in assessing
circulatory insufficiency in the brains of
patients with antiphospholipid antibodies and
neuropsychiatric symptoms but without
thromboembolism . -
pubmed
MATERIALS AND METHODS :
Patients with a history of positive antiphospholipid antibodies and
neuropsychiatric symptoms composed the case group ;
patients without antiphospholipid antibody served as the control group . -
pubmed
Tumor stage in
patients operated for rectal
cancer : a comparison of the pre - operative MR and the resection specimen , with specific attention to the effect of neo - adjuvant radiotherapy . -
pubmed
METHODS :
Patients diagnosed with
rectal cancer ( 2002 - 2015 ) and a pre - operative MR were included . -
pubmed
Underestimation as well as overestimation of the
tumor occurred both in the
patients treated with radiotherapy as well as those who underwent immediate operation . -
pubmed
Transcranial Magnetic Stimulation as an Additional Diagnostic Tool in
Children with
Acute Inflammatory Demyelinating Polyneuropathy . -
pubmed
SUBJECTS AND METHODS : Twenty healthy
children ( 7 - 14 years old ) without signs of
neurological disorders were enrolled as controls . -
pubmed
Thirty - seven
patients ( 8 - 13 years old ) with
AIDP were enrolled as the main group . -
pubmed
RESULTS : Significant differences between
children with
AIDP and controls on latencies of both cortical and lumbar MEPs were registered . -
pubmed
High - dose
Vit C has been investigated as a treatment for
cancer patients since the 1969 . -
pubmed
Despite many treatment options for
gout , there is a substantial need for alternative treatments for
patients unresponsive to current therapies . -
pubmed
Complete surgical resections are crucial for permanently curing
patients with
gastrointestinal stromal tumors (
GISTs ) . -
pubmed
Non - exposed endoscopic wall - inversion surgery ( NEWS ) for
patients with gastric
GISTs is a novel , minimally invasive surgical technique that may aid in complete resection of the
tumor margin by endoscopy and laparoscopy methods , removing the whole layer of the gastric wall and the entire
tumor , with decreased risk of peritoneal contamination or
tumor spread to the peritoneum . -
pubmed
To the best of our knowledge , the present study reports the first use of NEWS for a
patient with small
gastric GIST in Thailand . -
pubmed
Information on
HIV status is available in 63 % of cases , of which 7 % were
HIV - positive . -
pubmed
Nephrotoxic effects of
Valeriana wallichii . -
pubmed
Therefore , the current study was undertaken in an attempt to increase the use of these drugs without causing
nephrotoxicity by exploring the nephroprotective effects of a medicinal plant with high
flavonoid contents and strong antioxidant properties , namely
Valeriana wallichii . -
pubmed
The study group included
patients with surgically confirmed
anastomotic leaks ( n = 59 ) , and the control group included
patients without
anastomotic leaks ( n = 48 ) confirmed by either repeat surgery or uneventful clinical follow - up for at least 6 months . -
pubmed
BACKGROUND : To achieve the World Health Organization
hepatitis C virus (
HCV ) elimination targets , it is essential to increase access to treatment . -
pubmed
One thousand
patients with unilateral
hip disarticulation , trans - femoral amputation and
knee disarticulation due to war - related
injuries were invited to undergo a thorough physical examination . -
pubmed
The findings may be useful to adopt new strategies in planning rehabilitation programs to improve quality of life and health status of
patients with war - related
lower limb amputation . -
pubmed
CRISPR - based technologies have promise as a therapeutic platform for many
human genetic diseases previously considered untreatable , providing a flexible approach to high - fidelity gene editing . -
pubmed
Materials and Methods : A cohort of Medicare - eligible
patients discharged with the Diagnosis - Related Group ( DRG ) codes 480 to 482 (
hip and femur fractures requiring surgical fixation ) from a level 1
trauma center between October 2014 and September 2016 was evaluated and assigned a
trauma triage risk score ( STTGMA score ) . -
pubmed
EXPERT OPINION : The treatment of
hemophilia A with inhibitors by induction of immunotolerance and using by - passing concentrates , improved the quality of life of
patients but did not allow them to have a life expectancy like that of
patients without inhibitors . -
pubmed
Increased incidence of community - associated
Staphylococcus aureus bloodstream infections in Victoria and Western Australia , 2011 - 2016 . -
pubmed
CAR T - Cell Therapy in
Non - Hodgkin Lymphoma Patients . -
pubmed
Background / Objective : Although microRNA ( miRNA)-directed regulation of
bovine tuberculosis (
bTB ) has already been reported , very little is known about the incited pathways and genes . -
pubmed
It goes on to argue about its role as agents of domination of limitless profit interests and as an expression of the power of the health industry , justifying itself with the proposal of alternatives tending to overcome that network : transdisciplinarity and the concept of organism as hierarchical totality and interacting with its environment , with respect to disjunction and reductionism ; the cultural history of the
disease in relation to the health - disease binomial and the dehumanizing technologization ; good living , the search for spiritual , intellectual , moral and coexistence growth as meaning of
human life , as an alternative to the medicalization and antidote of degrading traits and stimulating medicine of the endogenous healing forces of the organism whose foundation of possibility and credibility is the placebo effect as an alternative to suppressive therapy for non - communicable chronic conditions , based on the pharmacological effect with unfailing side effects . -
pubmed
IgG4 - related disease in
patients with newly diagnosed
idiopathic retroperitoneal fibrosis : a population - based Danish study . -
pubmed
Individuals with
substance use disorders (
SUDs ) have to cope with drug - related cues and contexts which can affect instrumental drug seeking , as shown with Pavlovian - to - instrumental transfer ( PIT ) tasks among
humans and animals . -
pubmed
Identification of pre - diabetic
individuals with decreased functional ss - cell mass is essential for the prevention of
diabetes . -
pubmed
At the latest follow - up , the correction of
cubitus varus obtained was satisfying in the five cases of our series and all the
patients had
pain free elbow mobility . -
pubmed
Ulnar nerve
palsy complicated the evolution in one
patient , which fully recovered within 6 months . -
pubmed
Patients were included if they were between 20 and 80 years old and had a serum
uric acid ( sUA ) level > = 7.0 mg / dl with or without
gout , estimated
glomerular filtration rate ( eGFR ) of 15 - 60 ml / min/1.73 m2 , and urinary protein
creatinine ratio ( uPCR ) of 0.15 - 3.5 g / gCr . -
pubmed
Antigen - shift in
varicella - zoster virus - specific T - cell immunity over the course of
Fingolimod - treatment in
relapse - remitting
multiple sclerosis patients . -
pubmed
Analyzed samples comprised of different groups including 18
patients with
RRMS at baseline ( BL ) , 6 and 12 months after
FTY - treatment start , 12
patients with long - term ( LT )
FTY - treatment , one
FTY - treated
patient , before and after
VZV - reactivation . -
pubmed
However ,
VZV - specific immunity could be detected in the majority of
RRMS patients throughout
FTY - treatment with increasing prevalence after 6 months of treatment . -
pubmed
CONCLUSION : Monitoring
VZV - specific T - cell immunity might provide a valuable tool to
RRMS patient risk management during
FTY - treatment . -
pubmed
Pharmacotherapy combined with psychotherapy treatments for
gambling disorder may provide better rates of
patient retention in comparison to pharmacology - only treatments , though further research is needed in this area . -
pubmed
Over the past decade ,
human stem cell - derived brain organoids have emerged as a biologically relevant model system to study normal
human brain development and
neurological diseases . -
pubmed
The diagnosis of
EBV - associated lymphoproliferative disorder (
LPD ) was demonstrated by elevation of the plasmatic
EBV viral load . -
pubmed
Screening diversity and distribution of Copia retrotransposons reveals a specific amplification of BARE1 elements in genomes of the
polyploid Hordeum murinum complex . -
pubmed
RESULTS : Of the 23 Arab
patients with a median age of 64 years ( range , 36 - 87 years ) , eight had
hepatocellular carcinoma , four had
cholangiocarcinoma , and 11 had liver - only or liver - dominant
metastases from other primary
cancers . -
pubmed
The
mouse optic nerve crush ( ONC ) model has been widely used to study
optic neuropathies and central nervous system ( CNS )
axon injury and repair . -
pubmed
Previous histological studies of retinal
ganglion cell ( RGC )
somata in retina and axons in ON demonstrate significant neurodegeneration after ONC , but longitudinal morphological and functional assessment of RGCs in living
animals is lacking . -
pubmed
are susceptible to
infection by many plant - parasitic nematodes , including
Meloidogyne incognita . -
pubmed
We then conducted a group study on a dataset of in vivo MRI from
temporal lobe epilepsy (
TLE )
patients and healthy controls . -
pubmed
The method detected local thinning patterns in
patients , predominantly ipsilaterally to the
seizure focus , which is consistent with medical knowledge . -
pubmed
It shows good robustness with respect to anisotropy and inter - rater variability and has the potential to detect local
atrophy in
patients . -
pubmed
A total of 282
patients were included , of whom 56 had
brain metastases that were treated with upfront local radiation therapy in 80.3 % of
cases . -
pubmed
The overall response rate was 39.2 % and 44.4 % in
patients with and without brain
metastases ( P=0.48 ) , respectively , while intracranial response rate and intracranial disease control rate were 67.5 % and 85.0 % , respectively . -
pubmed
Drug discontinuation rate due to treatment - related adverse events was 10.7 % and 10.2 % in
patients with and without
brain metastases , respectively . -
pubmed
In
patients with
brain metastases , only PS > = 2 was predicted for a worse TTF ( P=0.02 ) and OS ( P=0.03 ) . -
pubmed
Presence of brain
metastases per se does not appear to be prognostic , and PS > = 2 seems to be the only factor associated with a worse outcome in
patients with
brain metastases . -
pubmed
The Effect of Peppermint (
Mentha piperita ) Extract on the Severity of
Nausea , Vomiting and
Anorexia in
Patients with
Breast Cancer Undergoing Chemotherapy : A Randomized Controlled Trial . -
pubmed
Background and Objective :
Nausea ,
vomiting , and
anorexia are the most common side effects reported in
cancer patients undergoing chemotherapy . -
pubmed
The present study aimed to determine the effect of peppermint extract on the severity of
nausea , vomiting , and
anorexia in
patients with
breast cancer undergoing chemotherapy . -
pubmed
Methods and Materials : In this randomized controlled trial , we selected 84
patients with
breast cancer undergoing chemotherapy . -
pubmed
Conclusion : The use of peppermint as a method in complementary medicine may improve
nausea ,
vomiting , and
anorexia in
patients with
breast cancer undergoing chemotherapy . -
pubmed
Meta - analysis of the effect of
vascular complications on mortality in
patients undergoing femoral venoarterial extracorporeal membrane oxygenation . -
pubmed
BACKGROUND : Extracorporeal membrane oxygenation ( ECMO ) has become an accepted treatment modality in the management of select
patients with
cardiopulmonary failure . -
pubmed
Increased GNRB risk in auto - HSCT
patients transplanted for
autoimmune diseases is worrying . -
pubmed
METHODS : We identified 176 PET - positive PANs on pretreatment PET / CT of 47
patients with diagnosed FIGO stage IB - IVA
cervical cancer . -
pubmed
The
children were observed for verbal , vocal , facial , and motor behavior during
diphtheria -
pertussis -
tetanus or
diphtheria -
tetanus injections . -
pubmed
The
children then rated the extent of
pain during the injection by responding to two instruments , a modification of Eland 's Projective Tool and Hester 's Poker Chip Tool . -
pubmed
[
Melanoma of the choroid in young
patients ] . -
pubmed
Of the four types of lesions treated ,
verruca vulgaris ,
condyloma acuminatum , and tattoos responded best . -
pubmed
Radiographs an patient histories of 36
children were examined in order to determine radiological signs that would allow a prediction or an early diagnosis of the
aseptic necrosis of the femur head nucleus (
Luxations - Perthes ) during the treatment of
hip dysplasia . -
pubmed
Necrosis of the nucleus appeared in 17 joints ( of 15
children ) . -
pubmed
The effects , in adult
animals , of
limbic lesions produced in infancy were studied in 273 male
Wistar rats using
weight gain and conditioned emotional response ( CER ) and conditioned avoidance response ( CAR ) acquisition as the critical measures . -
pubmed
In all 3
children there was a delay in diagnosis , and it is suggested that a
chronic intussusception should be considered more frequently in children with persistent
abdominal symptoms for which no cause can be found . -
pubmed
[ Experimental
infection with hepatitis E virus in
rhesus monkeys ] . -
pubmed
An experimental model of
hepatitis E was established in
Rhesus Monkeys . -
pubmed
Four animals were inoculated with stool suspensions that obtained from
patients with
hepatitis E. -
pubmed
After 4 - 6 weeks the
ALT of the four
animals infected
HEV raised 3 - 4 times and the live biopsy showed acidophilic degeneration of hepatocytes and coagulative liver cell
necrosis . -
pubmed
The case of a 71 - year - old
woman with
acute myelomonocytic leukaemia and severe
pains in her arms , legs and back during treatment is described . -
pubmed
The condition should be suspected whenever inexplicable
pain problems and signs of
peripheral neuropathy occur in
patients with
acute leukaemia . -
pubmed
Metabolic alkalosis and the response of the
trout ,
Salmo fario , to acute severe
hypoxia . -
pubmed
Trout (
Salmo fario ) were acutely transferred from seawater to freshwater in order to induce
blood metabolic alkalosis ( cf . -
pubmed
The results demonstrate that initial
blood alkalosis does not prevent the typical physiological responses of
trout to
hypoxia but simply shifts to lower PaO2 values the threshold at which these responses begin . -
pubmed
Hypophosphatemic vitamin D - resistant rickets is the most common form of
vitamin D - resistant rickets in
man . -
pubmed
The
hypophosphatemic mouse model ( Hyp ) is phenotypically and biochemically similar to the
human disease . -
pubmed
In 2 out of 9
patients with multifocal
demyelinating motor neuropathy , MRI showed focal
swelling of the nerve at the site of conduction block . -
pubmed
[ Enzymatic
protein hydrolysates for the nutrition of
children suffering from a
food allergy ] . -
pubmed
From an s.c.-passaged subline of an
ascites - converted
murine sarcoma (
SEWA - AS12 ) , we were able to separate cells adapted to the
ascites form of growth from cells that can only grow in the solid form on the basis of their differential adherence to plastic . -
pubmed
Vitreous fluorophotometry in
patients with
Best ' s macular dystrophy . -
pubmed
Ten
patients with
Best ' s macular dystrophy were examined with vitreous fluorophotometry and results were compared with a normal population . -
pubmed
[ Therapeutic tactics in
inflammatory diseases of the gallbladder in
patients with
bronchial asthma ] . -
pubmed
The authors describe curative methods of treatment of
inflammatory diseases of the gallbladder in 12
patients with
bronchial asthma . -
pubmed
Sanitation of the surgical
infection focus ( cholecystectomy ) improves the clinical course of
bronchial asthma , positively influences the immune status of the
patients . -
pubmed
One hundred and fifty - two
patients with
idiopathic scoliosis were treated at the Alfred I. duPont Institute with the Milwaukee brace between 1961 and 1972 . -
pubmed
This study includes 94
patients and was undertaken to evaluate the effectiveness of Milwaukee brace treatment in managing various sequelae associated with
idiopathic scoliosis , such as degree of curvature and trunco - pelvic alignment , and to assess the degree of spinal stability after treatment . -
pubmed
The tissue distribution of these radiolabeled compounds in
BDF1 mice bearing
Lewis lung tumors has been investigated . -
pubmed
Zimelidine , a selective inhibitor of
serotonin ( 5 - HT ) reuptake in the CNS , was administered to
narcoleptic patients . -
pubmed
Zimelidine , however , has no anticholinergic effect , so it is unlikely that cholinergic mechanisms thought to be important in
animal cataplexy would play a major role in
human cataplexy . -
pubmed
After exercise ,
NIDDM subjects had muscle glycogen concentrations comparable with those of lean and
obese subjects . -
pubmed
Septicaemia caused by
Rahnella aquatilis in an immunocompromised patient . -
pubmed
The control of
Ostertagia ostertagi infections in Australia is aimed specifically at young
cattle in their first and second year of grazing after weaning . -
pubmed
Cefoperazone plus
mezlocillin for empiric therapy of
febrile cancer patients . -
pubmed
Two dosing regimens of
cefoperazone plus
mezlocillin were compared in a prospective , randomized trial for therapy of
febrile cancer patients . -
pubmed
Although the overall response rate was higher with the higher dose regimen ( 78 percent versus 66 percent , p = 0.04 ) , the two regimens were comparable in
patients with documented
infections ( 72 percent versus 68 percent ) . -
pubmed
Hypoprothrombinemia was a side effect , especially with the higher dose regimen , before prophylactic
vitamin K was routinely administered to
patients . -
pubmed
[ The invasiveness of
cerebral gliomas in
patients of various ages ] . -
pubmed
We have described a 25 - year - old
man with an
idiopathic dilated biventricular cardiomyopathy and end - stage
glomerulonephritis due to
IgA nephropathy , who was found incidentally at angiographic examination to have an anomalous right coronary artery arising from the main pulmonary artery . -
pubmed
The purpose of this report is to present a 5 year experience in electrophysiologically guided surgical treatment of
post - infarction ventricular tachycardia (
VT ) in a consecutive series of 39
patients . -
pubmed
In conclusion , long - term
methandienone treatment results in
cardiac hypertrophy in
dogs , reduces its response to an inotropic loads and leads to working on larger ventricular volumes . -
pubmed
Lung pathology studies revealed neutrophilic
alveolitis with intraalveolar and intracapillary neutrophil infiltration in the C5'-treated
animals . -
pubmed
In the experimental group ,
bilirubin was infused for 4 h. The cerebral
bilirubin content in the
bilirubin - infused group was 11.0 + /- 1.4 nmol / g of cerebral cortex ( mean + /- SEM ) , consistent with levels found in
infants with
kernicterus . -
pubmed
Dietary
glucarate - mediated reduction of sensitivity of
murine strains to chemical
carcinogenesis . -
pubmed
The level of the enzyme in the
murine strains is shown to correlate with the urinary excretion of
17 - ketosteroids , which in turn reflects the endogenous level of
androgens . -
pubmed
Sensitivity of the
A / He strain is significantly reduced by dietary
calcium glucarate , which is shown to inhibit DNA binding and the induction of
pulmonary adenomas by
benzo [ a ] pyrene . -
pubmed
Electroencephalograms of anesthetized
dogs with
hydrocephalus . -
pubmed
Ten ( 9.3 % ) of 107
patients with
hepatocellular carcinoma had considerably increased serum unsaturated
vitamin B12 binding capacity . -
pubmed
Glucose intolerance in
children with
chronic renal failure . -
pubmed
Carbohydrate metabolism was studied by the
hyperglycemic clamp technique in 14
children with moderate to severe
chronic renal failure (
CRF ) ( 8 pubertal and 6 prepubertal ) and was compared with 5 healthy prepubertal
children and 7 healthy young adults . -
pubmed
Children with
CRF were
glucose intolerant ( lower M ) ,
hyperinsulinemic ( higher I ) , and
insulin resistant ( lower M / I ) compared with the control children . -
pubmed
Pubertal
children with
CRF had lower M and lower M / I compared with prepubertal
children with
CRF . -
pubmed
M and M / I correlated with
glomerular filtration rate (
GFR ) in the 8 pubertal
children , while M / I also correlated with
GFR in the 6 prepubertal
children with
CRF . -
pubmed
Carcinogenesis studies of
L - ascorbic acid were conducted by offering diets containing 0 , 25,000 or 50,000 ppm
L - ascorbic acid to groups of 50 F344 / N
rats and 50
B6C3F1 mice of each sex for 103 wk . -
pubmed
Studies on the inheritance of
vaginal septa in
mice , a trait with low penetrance . -
pubmed
Cerebral angiographic findings of 32 Japanese
patients with carotid system
TIA 's were compared with those of an equal number of age and sex matched American Caucasians . -
pubmed
[ Metabolism of biogenic
amines in
patients with active
pulmonary tuberculosis complicated by nonspecific
endobronchitis ] . -
pubmed
Thirty - nine
patients with severe
cardiac failure and a previous transmural
myocardial infarct were studied prospectively to assess the ability of M - mode echocardiography to detect resectable
left ventricular aneurysms . -
pubmed
Subsequent angiography showed an
aneurysm in 23
patients and diffuse left
ventricular damage in 16 . -
pubmed
Nine ( 57 % ) of the
patients without
aneurysm had either left ventricular end - systolic dimensions in excess of 6 cm combined with reduced contraction of the base of the left ventricle ( fractional shortening of the level of the mitral valve less than 20 % ) , or gross reduction of contraction ( fractional shortening less than 15 % ) regardless of left ventricular dimension . -
pubmed
In 21 ( 91 % ) of the
patients with a
left ventricular aneurysm its presence was correctly predicted either by fractional shortening in excess of 20 % ( 16 patients ) or gross delay of mitral valve opening ( greater than 80 ms 16 patients ) . -
pubmed
coli
strains , 33 % possessed
O6 ,
O8 , or
O78 ; 93 % of these were stable producers of LT , and 86 % produced both Lt and ST . -
pubmed
coli
strains might be considered as true enteropathogenic bacteria ( enterovirulent
E. - pubmed
Electroencephalographic and evoked response correlates of
trimethyltin induced
neuronal damage in the
rat hippocampus . -
pubmed
Trimethyltin produces localized
neuronal damage in the
rat hippocampus , amygdala and pyriform cortex when given systemically . -
pubmed
This was a double - blind study designed to compare the efficacy and tolerability of
diclofenac /
misoprostol and
diclofenac in
patients with acute
tendinitis /
bursitis of the shoulder . -
pubmed
Abdominal pain ,
nausea and
vomiting occurred somewhat more frequently with
diclofenac /
misoprostol , but
patient withdrawals due to adverse events did not differ markedly between the groups . -
pubmed
Integrity and characteristics of secondary oesophageal peristalsis in
patients with
gastro - oesophageal reflux disease . -
pubmed
The aim of the study was to evaluate the integrity and characteristics of secondary peristalsis in
patients with
gastro - oesophageal reflux disease . -
pubmed
Studies were performed in 22
patients with
reflux disease and 20 age matched controls . -
pubmed
It was found that primary peristalsis was normal in 19 of 20 control subjects and in 14 of 22
patients with
reflux disease . -
pubmed
In
patients with
reflux disease , intact secondary peristalsis was triggered infrequently by air and water distension ( median success rate of 0 % for both stimuli ) and occurred significantly less frequently than in control subjects ( 50 % and 30 % respectively ) . -
pubmed
Peristaltic velocity for air and balloon induced secondary peristalsis was also similar in control subjects and
patients with
reflux disease whereas water induced secondary peristalsis was slower in the reflux patients . -
pubmed
Oral tolerance therapy has recently been applied to several
human autoimmune diseases . -
pubmed
One hundred and thirty - three Caucasian
patients ( 26
males ) with
GD and 85 local controls were included in this study . -
pubmed
[
Meningoencephalitis caused by
Yersinia enterocolitica ] . -
pubmed
AIDS - associated
strains of
M. - pubmed
Lupus nephritis in children -- a review of 167
patients . -
pubmed
BACKGROUND : Relatively few studies have been made of
children with
lupus nephritis . -
pubmed
The prognosis of
children with
lupus nephritis is ominous for those with diffuse proliferative
glomerulonephritis and active
interstitial inflammation . -
pubmed
OBJECTIVES : To evaluate the clinical course , histopathology , and prognosis of
lupus nephritis in
children , to identify the risk factors for
renal failure and mortality , and to share our experience in treating
lupus nephritis in
children . -
pubmed
METHODS : Retrospectively , 167
children under 18 years of age with
lupus nephritis at Veterans General Hospital - Taipei , Taiwan from 1979 to 1991 were studied . -
pubmed
All
children surviving without
renal failure were maintaining their normal lives with little organ dysfunction . -
pubmed
Spontaneous
GNBM appeared to have a sudden onset , a relatively fulminant course , and was caused most often by
Escherichia coli . -
pubmed
There were signs that many of the
schizophrenic patients , especially the men , used the emergency rooms as a means of
human contact and a " shelter " , compensating for the lack of a more personal social network . -
pubmed
For many years
patients with
sepsis and
septic shock have been treated with antibiotics , fluids , surgery ( if indicated ) and , in the more severe cases , inotropic and ventilatory support . -
pubmed
One hundred eleven
patients ( 89
PMR , 14
TA and 8 PMR+
TA ) were studied . -
pubmed
In 56
patients with
PMR a temporal artery biopsy was performed ; in none of these biopsies was active
arteritis found . -
pubmed
Of the 19
patients with
TA or
PMR+
TA , where a temporal artery biopsy was performed ,
arteritis was found in 15
patients . -
pubmed
Side effect of the medication included
vertebral compression in 10
patients , most of whom were using
corticosteroids . -
pubmed
Malignancies were diagnosed in 12 of the 111
patients . -
pubmed
Cytotoxic potencies of the drugs was tested against four representative
human tumor cell lines :
SKOV3 ,
SKLVB ,
HT29 , and
KB . -
pubmed
Vertebral artery dissection ( VAD ) is an important cause of
posterior circulation stroke in young
adults . -
pubmed
Between 1989 and 1995 we identified 24
patients with a
vertebral artery dissection and 1
patient with a
basilar artery dissection ( 8
females and 17
males , 23 - 60 years of age , mean 41.2 years ) . -
pubmed
Follow - up examinations revealed recanalization in 52 % of initially stenosed or occluded vertebral arteries ; four
patients developed a
pseudoaneurysm , and two of them underwent ligation of the VAD . -
pubmed
METHODS : In the July / August 1995 issue of APIC News , the committee published a survey on the prevalence of
infection control " sacred
cows , " practices considered to be outdated and ritualistic . -
pubmed
We studied the acute ventilatory response to
hypoxia ( AHVR ) in 10
patients with chronic
heart failure (
CHF ) and in 10 subjects with normal left ventricular function ( NLVF ) before and after 8 weeks of home - based physical training . -
pubmed
The AHVR is not substantially altered in
patients with
CHF compared to subjects with
NLVF . -
pubmed
However , exercise increases the AHVR in
patients with
CHF , as it does in normals . -
pubmed
These data suggest that the abrupt addition of
desflurane may have adverse consequences in
patients at risk for
intracranial hypertension . -
pubmed
We suggest that
FDG - PET seems to be useful in differentiating recurrent
tumor from
radiation necrosis in
patients with
liposarcoma after therapy . -
pubmed
Use of
DHEA in a
patient with advanced
prostate cancer : a case report and review . -
pubmed
A
patient with advanced
prostate cancer with progressive symptomatology was treated with
DHEA after other treatment regimens failed . -
pubmed
METHODS : The minimum inhibitory concentration ( MIC ) to
ampicillin /
sulbactam ( A / S ) ,
amoxycillin /
clavulanic acid ( A / C ) ,
ticarcillin /
clavulanic acid ( T / C ) and
piperacillin /
tazobactam ( P / T ) assessed was in 245
strains of
E. - pubmed
Retrospective analysis of results of electromyography and nerve conduction velocity was performed in 169
patients with
lower back pain , mostly caused by
trauma . -
pubmed
Peripheral entrapment of nerves (
tarsal tunnel syndrome and
anterior tarsal tunnel syndrome ) were found in 5.3 % of
patients , signs of acute or chronic partial
muscle denervation of corresponding muscles of lower extremities in 21.8 % of
patients , and abnormally prolonged F - wave latency in 12.5 % of
patients . -
pubmed
We describe a case of a young
patient carrying the mutation , with an
AMI caused by large bilateral intracoronary
thrombi , that underwent direct PTCA . -
pubmed
OBJECTIVE : To determine the effects of the
nitric oxide (
NO ) precursor
L - arginine on the airway
NO concentration in
patients with
preeclampsia . -
pubmed
No
patient required reoperation for treatment of a
fistula . -
pubmed
Six
patients with
uncomplicated falciparum malaria received
artesunate for 5 days . -
pubmed
A chronic
coronary occlusion of & gt ; or = 1 month duration ( range 1 to 33 months ; median 3.3 ) was successfully recanalized in 41
patients . -
pubmed
Early reocclusion ( subacute stent
thrombosis ) was observed in 1
patient ( 2.4 % ) . -
pubmed
Investigations with 52
patients indicated that volumes of & gt ; 100 microliters are rarely required for topical treatment of
condylomata . -
pubmed
Effects of
dexamethasone on
meconium aspiration syndrome in newborn
piglets . -
pubmed
We examined the effects of
dexamethasone on lung function in a
piglet model of
meconium aspiration syndrome . -
pubmed
We induced
lung injury in 10 newborn
piglets ( age 5 + /- 0.2 d ) with 4 mL / kg body weight of 20 % sterile
human meconium in normal saline given via tracheostomy . -
pubmed
In summary , a two - dose course of 0.5 mg / kg of
dexamethasone improved blood gases and lung function in a
piglet model of
meconium aspiration syndrome . -
pubmed
Then a laboratory experiment was conducted in order to construct a computer simulation model (
human model ) that describes
human cognitive behaviour on detecting and diagnosing
plant anomaly causes . -
pubmed
AIMS :
Ulcerative colitis is predominantly a disease of
nonsmokers and transdermal
nicotine has therapeutic value in active disease ; however side - effects are troublesome . -
pubmed
Clinically , no reaccumulation of
pleural effusion for at least 4 weeks was observed in four
patients . -
pubmed
In this report , a 25 - year old
patient developing
pneumothorax while on the treatment for
miliary tuberculosis treatment is presented and the related literature has been reviewed . -
pubmed
Adult male
Sprague - Dawley rats were subjected to 90 min intraluminal
middle cerebral artery occlusion and the drug was administered intravenously immediately or 2 h after reperfusion . -
pubmed
However , this high level of overexpression is associated with
bradycardia and increased incidence of
arrhythmia during
ischemia in intact
mice , which interfered with studies to determine whether this line of TG
mice might also be protected against
myocardial infarction (
MI ) in vivo . -
pubmed
METHODS : The comet assay was used to quantify nuclear DNA damage in neutrophils from
SLE patients ( n = 20 ) , control subjects ( n = 15 ) and
RA patients ( n = 15 ) . -
pubmed
Thus in the age of expensive polypharmacy with some degree of untoward reactions , immunotherapy may be helpful in selected allergic and
asthmatic patients . -
pubmed
Cross protection by
strains of
tomato spotted wilt virus and a new theory to explain it . -
pubmed
CARDIOVASCULAR MANIFESTATIONS OF THE
HURLER SYNDROME : HEMODYNAMIC AND ANGIOCARDIOGRAPHIC OBSERVATIONS IN 15
PATIENTS . -
pubmed
Sixty - eight
patients admitted with
CAP were included . -
pubmed
Juxtaglomerular apparatus T - cell infiltration affects glomerular structure in
Type 1 diabetic patients . -
pubmed
METHODS : We classified 89
Type 1 diabetic patients by immunohistochemical analysis as either juxtaglomerular apparatus T - cell positive ( n=37 ) or
T - cell negative ( n=38 ) . -
pubmed
Thus , juxtaglomerular apparatus immunologic
injury in
Type 1 diabetes patients could delay the clinical consequences of
diabetic nephropathy . -
pubmed
In vivo , XID
mice show reduced severity of
inflammatory diseases in models of
experimental autoimmune encephalomyelitis (
EAE ) , dextran sulfate
sodium ( DSS)-induced
colitis , and carrageenan - induced acute
edema . -
pubmed
Also , polymorphonuclear neutrophil granulocytes ( PMNs ) in XID
mice show poor ROI and
nitric oxide (
NO ) induction , along with a reduction in PMN recruitment to
peritoneal inflammation . -
pubmed
A prospective randomized study for the treatment of
bone loss with
vitamin d during kidney transplantation in
children and
adolescents . -
pubmed
Apart from transient
hypercalcemia in 1
patient in group 2 , no other significant adverse effects were noted . -
pubmed
METHODS : Ninety - five
AAA patients undergoing EVR had the endografts implanted percutaneously via 14 - F to 20 - F sheaths in a prospective nonrandomized study . -
pubmed
Blood loss , operative time , and length of stay ( LOS ) were compared to 26
AAA patients undergoing EVR with bilateral femoral cutdowns before the percutaneous technique was available . -
pubmed
Neuronal tissue transplantation is a potential way to replace degenerated spiral
ganglion neurons ( SGNs ) since these cells can not regenerate in adult
mammals . -
pubmed
CONCLUSION(S ): Although concerns remain concerning distension and potential
injury resulting from use of the system , enough data have been gathered to warrant further study of this material for use in
humans . -
pubmed
We present the case of a
patient who presented with recurrent
syncope . -
pubmed
METHODS : To quantify the concentration of conjugated
DX-8951 ,
DX-8951 and
G - DX-8951 in
human tissues , six
patients with different solid
tumor types received 6.0 mg / m(2 ) of
DE-310 ( as equivalent of
DX-8951 ) as a single three - hour infusion administered 7 days ( + /-2 days ) prior to scheduled
tumor resection . -
pubmed
Concentrations of conjugated
DX-8951 ,
DX-8951 and
G - DX-8951 were in general similar in
tumor and relevant normal tissue samples and preferential accumulation of
DE-310 ,
DX-8951 and
G - DX-8951 in
human tumor tissues was not observed . -
pubmed
Cysteamine , the dimer of
cystamine , is an orphan drug approved for the treatment of
nephropathic cystinosis and has a similar benefit in the
murine model but with a narrower therapeutic window . -
pubmed
In a single - center open - label study , we determined the maximum tolerable dose ( MTD ) and side effects of
cysteamine in
people with
Huntington ' s disease . -
pubmed
We conclude that , at a dose of 20 mg / kg per day ,
cysteamine was tolerable in
people with
Huntington ' s disease . -
pubmed
RESULTS : The technique was used in the treatment of six
patients with recurrent
ankylosis of the mandible ranging in age from 9 to 38 years . -
pubmed
OBJECTIVES : To determine whether
children with prenatally diagnosed mild
pyelectasis have more urinary tract morbidity during childhood than
children without this finding . -
pubmed
METHODS : Case - control study in
children with
pyelectasis ( anteroposterior diameter of the fetal renal pelvis of 5 - 10 mm ) . -
pubmed
We present the case of a 32 - year - old
woman suffering who suffered from mild
intracranial hypertension ,
gait disturbance and
vertigo for one year . -
pubmed
Reconstitution with
human cells can be achieved using large numbers of peripheral blood lymphocytes , but levels of engraftment are poor and
graft versus host disease (
GVHD ) frequently occurs . -
pubmed
In conclusion , we show that intraperitoneal injection of 30 - 40 x10(6 )
human splenocytes into
SCID / beige mice induces a quick and functional engraftment of
human T , B and NK cells with no risk of
GVHD . -
pubmed
The
chromosome aberration assay in the bone marrow cells of
C57BL / 6 mice was used to study the cytogenetic activity of
ribavirin ( 10 , 50 , 100 , 200 , and 400 mg / kg , p.o . ) -
pubmed
We have reported the isolation of the
tetranortriterpenoid 1 - cinnamoyl-3,11 - dihydroxymeliacarpin (
CDM ) from partially purified leaf extracts of
Melia azedarach L. ( MA ) that reduced both ,
vesicular stomatitis virus ( VSV ) and
Herpes simplex virus type 1 (
HSV-1 ) multiplication . -
pubmed
Twenty
children had surgery alone ; eight ( 40 % ) experienced
recurrence ; and four died . -
pubmed
Eighteen
children had surgery and adjuvant chemotherapy ; one experienced
recurrence and died . -
pubmed
Four of nine
children with
recurrence survived . -
pubmed
CONCLUSION : Adjuvant chemotherapy appears to benefit
type I PPB patients . -
pubmed
OBJECTIVE :
Low bone mineral density has repeatedly been reported in
patients with
major depressive disorder (
MDD ) , and
MDD has been discussed as a risk factor for the development of
osteoporosis . -
pubmed
MDD in young
adults often occurs in the context of
borderline personality disorder (
BPD ) , and both
MDD and
BPD have been associated with a dysregulation of the hypothalamic - pituitary - adrenal system and subsequent
hypercortisolemia . -
pubmed
To date , it is unclear whether comorbid
BPD in depressed
patients modulates the extent of bone mass reduction . -
pubmed
Patients with
BPD alone and healthy women served as comparison groups . -
pubmed
METHOD : Twenty - four
patients with
MDD and 23
patients with comorbid
MDD and
BPD were included . -
pubmed
Sixteen
patients with
BPD and 20 healthy
women of similar
body mass index served as the comparison group . -
pubmed
For data analysis , the group of depressed
patients without comorbid
BPD was divided according to age into two groups ( younger depressed
patients with a mean age of 30 years and older
patients with a mean age of 42.9 years ) . -
pubmed
CONCLUSION :
Depression is associated with
reduced bone mass , in particular in
patients with comorbid
BPD . -
pubmed
We conclude from our data that a history of
MDD with and without comorbid
BPD should be considered as a risk factor in clinical assessment instruments for the identification of
persons prone to
osteoporosis . -
pubmed
PDT was administered to
NR - S1 mouse squamous cell carcinoma or normal
mouse skin . -
pubmed
The
patients have quick functional recovery , as evaluated by the length of
postoperative ileus ( 60.0 + /- 12.0 h ) , hospitalization ( 9.0 + /- 1.5 days ) and degree of
postoperative pain ( 4.0 + /- 0.5 , visual analogue scale ) . -
pubmed
Patients with
acute coronary syndrome ( n=148 ) were followed after an initial attack for subsequent
ischemic cardiovascular events ( composite end point of
death ,
myocardial infarction , recurrent
unstable angina , or
stroke ) . -
pubmed
The
cataract phenotype gave the appearance like a " pearl box " in these two affected
individuals of this family . -
pubmed
In planning treatment for
cancer patients , it is critical to avoid inappropriate treatment decisions based on misdiagnosis of a benign lesion as a
metastasis or primary
liver malignancy . -
pubmed
Both groups were subdivided in
patients with
hypogonadism and normal gonadal function . -
pubmed
Matched pairs of
patients with
stroke , with and without lateropulsion , were compared for functional outcomes and discharge destination following inpatient rehabilitation . -
pubmed
METHODS : A retrospective chart review of
patients with
ischemic stroke at an inpatient rehabilitation hospital matched 36 pairs of
patients with versus without lateropulsion . -
pubmed
Lower extremity
weakness was greater in the lateropulsion group at discharge ;
patients with
right brain damage accounted for this difference . -
pubmed
Patients with lateropulsion required more dependent living situations at discharge , especially if they had right
brain damage . -
pubmed
The establishment of temperature - sensitive mutant
strains of
T. - pubmed
The temperature - sensitive mutant ts-4
strain disappears from tissues of immunocompetent
mice without forming tissue
cysts and induces protection against challenge with virulent
strains of the parasite , and a protocol is provided for
infection with this mutant
strain . -
pubmed
Support protocols present methodology for evaluation of progression of
infection and immune response to the parasite , maintenance of
T. - pubmed
gondii tissue
cysts and tachyzoites , as well as preparation of
T. - pubmed
A 72 - year - old
man born in Arizona with a heavy smoking history , presented with a 1 - month history of
weakness ,
night sweats ,
exertional dyspnea , and left pleuritic
chest pain . -
pubmed
OBJECTIVES : Current indications for therapeutic
hypothermia (
TH ) are restricted to
comatose patients with
cardiac arrest (
CA ) due to
ventricular fibrillation (
VF ) and without
circulatory shock . -
pubmed
Additional studies are needed to evaluate the benefit of this treatment in more heterogeneous groups of
patients , including those with non - VF rhythms and/or
shock and to identify early predictors of outcome in this setting . -
pubmed
INTERVENTIONS : TH to 33 + /- 1 degrees C ( external cooling , 24 hrs ) was administered to
patients resuscitated from
CA due to
VF and non -
VF ( including
asystole or pulseless electrical activity ) , independently from the presence of
shock . -
pubmed
Seventy - four
patients ( VF 38 , non - VF 36 ) were included ; 46 % had
circulatory shock . -
pubmed
CONCLUSIONS : Time from collapse to
ROSC is strongly associated with outcome following VF and non - VF
cardiac arrest treated with therapeutic
hypothermia and could therefore be helpful to identify
patients who benefit most from active induced cooling . -
pubmed
All
patients were satisfied with the
scar mark . -
pubmed
Total RNA of CD3 + T cells isolated from six
RRMS patients taken at the peak of acute
relapse and at the point of complete remission was processed for DNA microarray analysis . -
pubmed
However , nowadays many
obese patients are treated with lipid lowering drugs before the start of
sibutramine therapy and their effects in these
patients have not been investigated . -
pubmed
Primary outcomes were time to
patient death and graft loss , complications and renal function . -
pubmed
Between 1997 and 2007 , 2427
strains of
Streptococcus pneumoniae were isolated in part from cerebrospinal fluids , blood and middle ear fluid , from children and adults . -
pubmed
After surgery two
patients developed an intra - abdominal
abscess , drained laparoscopically or percutaneously , and one patient had another site - specific
infection . -
pubmed
We investigated
vancomycin and
daptomycin efficacy for
Staphylococcus aureus isolates at our institution by testing 221
methicillin - sensitive and 299
methicillin - resistant isolates recovered from serious
infections between 1979 and 2007 using a microdilution method . -
pubmed
Of the
patients with invasive
fungal infections , 33.6 % were homozygous extensive metabolizers , 50.0 % heterozygous extensive metabolizers and 16.4 % poor metabolizers . -
pubmed
It is presently unknown whether
mtDNA abnormalities are present in single
human ALS neurons . -
pubmed
Carotid blowout is a devastating complication in
patients with
head and neck malignancy , and is associated with high morbidity and mortality . -
pubmed
For
patients with
bleeding originating in the internal or common carotid artery , treatment options are limited . -
pubmed
We describe two cases of pseudoaneurysmal
rupture in the common carotid artery with massive
bleeding in
patients with
head and neck malignancies and a history of long - term radiation treatment . -
pubmed
Although these endovascular treatments often result in recurrent
carotid blowout syndrome , they can be useful and effective in treating emergent
carotid rupture in
patients for whom balloon occlusion test is contraindicated . -
pubmed
BACKGROUND : Epidemiology and imaging studies showed that cognitively normal ( NL )
individuals with a maternal history ( MH ) of late - onset
Alzheimer ' s disease (
LOAD ) might be at increased risk for
Alzheimer ' s disease (
AD ) compared with
NL with a paternal history (
PH ) and
NL with a negative family history of
LOAD (
NH ) . -
pubmed
METHODS : Fifty - nine 40 - 80 - year - old NL
subjects were examined , including 23
MH and 14
PH whose parents had a clinician - certified diagnosis of
LOAD and 22 NH . -
pubmed
A multicenter phase - II study of
5 - FU ,
leucovorin and
oxaliplatin (
FOLFOX6 ) in
patients with pretreated metastatic
colorectal cancer . -
pubmed
OBJECTIVE : Infusional
5 - fluorouracil and
leucovorin with
oxaliplatin is one of the standard regimens for
patients with pretreated metastatic
colorectal cancer , as well as for first - line chemotherapy . -
pubmed
The objective of this study was to evaluate the efficacy and safety profile of
FOLFOX6 in Japanese
patients with pretreated
colorectal cancer . -
pubmed
METHOD : Fifty - one metastatic
colorectal cancer patients who failed to respond to first - line chemotherapy were enrolled in the study from April to July 2005 . -
pubmed
CONCLUSION : The results of our study suggest that
FOLFOX6 had an acceptable profile in terms of both efficacy and safety in previously treated
colorectal cancer patients . -
pubmed
Patients with
trigeminal neuralgia , a rare facial
neuropathic pain , present to both medical and dental specialists . -
pubmed
[ Diagnosis and therapy of a
dog with an atypical
eosinophilic cellulitis ] . -
pubmed
A 6 years old female bernese mountain
dog was seen for a nodular and erythemato - edematous
dermatosis resistant to therapy . -
pubmed
The histopathological exam showed a eosinophilic
cellulitis with flame figures , which are caracteristic for the
Wells ' syndrome in
human . -
pubmed
The
children who have had a history of
painful crisis 1 - 4 , 5 - 10 , and over 10 times were classified as group 1 , group 2 , and group 3 , respectively . -
pubmed
The
depression levels of the
children in group 3 were higher than group 1 ( P = .018 ) . -
pubmed
Typically ,
patients are diagnosed through exclusion of
neurological disease and the absence of pathologic neurophysiological diagnostic findings . -
pubmed
Here , we investigate the neural basis of this disorder by combining electrophysiological ( event - related potentials ) and hemodynamic measures ( functional magnet resonance tomography ) in a
patient with
hysterical blindness before and after successful treatment . -
pubmed
DESIGN , SETTING , AND PARTICIPANTS : Forty - four consecutive
patients who underwent laparoscopic partial nephrectomy ( LPN ) or robot - assisted partial nephrectomy ( RAPN ) from June 2008 to May 2009 for a single cT1
renal tumour were included in this prospective protocol . -
pubmed
A 42 year old
man with bilateral
exophthalmos and
weight loss . -
pubmed
METHODS : In vitro the
human synovial sarcoma cell line
SW982 , the
murine fibrosarcoma cell line
BFS-1 and primary
human fibroblasts as a control were exposed to
[ D ]- K3H3L9 , a 15mer
D , L - amino acid designer HDP . -
pubmed
The local intratumoral administration of
[ D ]- K3H3L9 in the athymic and
syngeneic mice models significantly inhibited
tumor progression . -
pubmed
BACKGROUND : Understanding transmission dynamics of the pandemic
influenza A ( H1N1 ) virus in various exposure settings and determining whether transmissibility differed from seasonal
influenza viruses was a priority for decision making on mitigation strategies at the beginning of the pandemic . -
pubmed
CONCLUSIONS : Secondary attack rates for
pandemic influenza A ( H1N1 ) were comparable to seasonal
influenza estimates suggesting similarities in transmission . -
pubmed
METHODS AND RESULTS : OPTIMAL was an observational , prospective study undertaken at 79 medical centres in France in
patients with
STEMI undergoing pre - hospital thrombolysis ( PHT ) within six hours of symptom onset and coronary angiography within six hours of thrombolysis . -
pubmed
PATIENTS / METHODS : Twenty - seven
SCAD patients underwent a 5 - year follow - up ( 13
males , 14
females ; mean age , 63.71 years ; range , 50 - 85 years ) . -
pubmed
Eleven
patients were affected by type A , eight by type B , four by type C and four by
type D SCAD . -
pubmed
MATERIALS AND METHODS : Left - hand radiographs of 679
children ( 375
boys ) ranging in age from 1 day to 18 years old were obtained for
trauma in the period 2001 - 2009 and were evaluated for bone age according to G&P. Individual bone age was plotted against calendar age and smoothed to obtain the association between calendar age and bone age . -
pubmed
Evaluation of
multiple myeloma patients presenting with
renal failure in a university hospital in the year 2010 . -
pubmed
BACKGROUND : The aim of this cross - sectional study was to evaluate
multiple myeloma patients presenting with
renal failure in a University hospital . -
pubmed
METHODS : The records of all the
patients diagnosed with
multiple myeloma in the departments of hematology and nephrology at Gazi University Hospital between January 2010 and January 2011 were reviewed retrospectively . -
pubmed
RESULTS : Eight ( 26.7 % ) of the 30
patients had
renal failure and 4 ( 50 % )
patients with
renal failure required renal replacement therapy with hemodialysis after admission . -
pubmed
In one of the eight
patients ( 12.5 % )
creatinine levels improved , but did not reach the level defined as reversal of
renal failure . -
pubmed
The renal functions of the three ( 37.5 % )
patients did not improve and they remained on chronic hemodialysis program during which one of them died due to a
cerebrovascular accident and one other
patient was lost due to follow - up . -
pubmed
We also review studies with
mice , which demonstrate that nutritional supplementation can alleviate multiple genetic risk factors for
AD . -
pubmed
OBJECTIVE : To estimate the prevalence of
virus C hepatic infection and to illustrate the various socio - economic , behavioural and medical factors related to
infection with Hepatitis C (
HCV ) among apparently healthy individuals . -
pubmed
Patients with
PKD were aged 58 + - 13 years and included 46 % women 14 % Blacks , respectively . -
pubmed
SNP genotyping identifies new signatures of selection in a deep sample of
West African Plasmodium falciparum malaria parasites . -
pubmed
We used a high - density single - nucleotide polymorphism array to genotype 75
Plasmodium falciparum isolates recently collected from Senegal and The Gambia to search for signals of selection in this
malaria endemic region . -
pubmed
Bambusa textilis McClure is a traditional Chinese medicinal plant belonging to the Bambusoideae subfamily and used to treat
chronic fever and
infectious diseases . -
pubmed
Improved neurologic prognosis for a
patient with
propionic acidemia who received early living donor liver transplantation . -
pubmed
Despite medical therapy ,
patients with
propionic academia (
PA ) still display a tendency to develop
epilepsy . -
pubmed
Patients with neonatal - onset
PA who have received early living donor liver transplantation ( LDLT ) are limited in number , and the effect on neurologic prognosis , including
epilepsy , is not clear . -
pubmed
We report a
patient with
PA whose EEG findings improved dramatically after undergoing LDLT at age 7 months . -
pubmed
The survey of diastolic function changes in
end - stage renal disease patients before and 3 and 6 months after kidney transplantation . -
pubmed
INTRODUCTION :
Left ventricular diastolic dysfunction , which is prevalent in
end - stage renal disease , predicts morbidity and mortality among affected
patients . -
pubmed
The aim of this study was to evaluate diastolic function changes in
end - stage renal disease patients before as well as 3 and 6 months after kidney transplantation . -
pubmed
PURPOSE : This study was carried out to determine the ocular pharmacokinetics , efficacy and potential endothelial
toxicity of
moxifloxacin ( MF ) after a single intracameral bolus injection of 500 microg/0.1 ml in a
rabbit model . -
pubmed
RESULTS :
Moxifloxacin reaches higher concentration than the MIC of all common
endophthalmitis pathogens in the AH and exceeds the mutant prevention concentration levels for
Streptococcus pneumonia ,
Streptococcus viridans ,
flouroquinolone susceptible Coagulase - negative staphylococcus and
flouroquinolone susceptible
Staphylococcus aureus for 6 h. The half - life of
moxifloxacin in the AH was 2.2 h. Electron and light microscopic evaluation revealed no noticeable sign of
toxicity . -
pubmed
PURPOSE : Indications that the prenatal action of
testosterone in the brain is an important determinant of gender development and improved reconstructive techniques have caused a shift in male gender assignments in
patients with
46XY disorders of sex development . -
pubmed
MATERIALS AND METHODS : Physical status of 14
men with a mean age of 25 years with
disorders of sex development was assessed by structured interview and physical examination . -
pubmed
Ejaculatory dysfunction was reported by 7
men . -
pubmed
These
patients reported
decreased sexual desire and activities . -
pubmed
Improved survival and quality of life in
patients undergoing R1 pancreatic resection compared to
patients with locally advanced unresectable
pancreatic adenocarcinoma . -
pubmed
CONCLUSION : Radical removal ( R0 resection ) is the primary aim of surgery , but also R1 resection seems to improve survival and QoL , compared to outcome in
patients with locally advanced
tumours not undergoing surgery . -
pubmed
Osteomalacia induced by
vitamin D deficiency in hemodialysis
patients : the crucial role of
vitamin D correction . -
pubmed
Data in the literature are however scarce about the effects of this deficiency on bone metabolism in hemodialysis (
HD )
patients . -
pubmed
Moreover , it is still debated whether low
vitamin D levels should be normalized in
HD patients . -
pubmed
In this paper , we report two cases showing the deleterious consequences of
vitamin D deficiency in
HD patients which is characterised by
hypophosphatemia ,
hypocalcemia and
osteomalacia (
OM ) leading to
bone fractures . -
pubmed
Adrenal metastases are usually solitary , asymptomatic and diagnosed incidentally during staging of
patients with
lung cancer . -
pubmed
Bilateral adrenal
metastases at the time of diagnosis are seen in 3 % of
lung cancer patients . -
pubmed
Herein we describe a 46 - year old male
patient with
SCLC who was symptomatic from large bilateral
adrenal metastases at presentation . -
pubmed
The
patient was successfully treated with conventional
platinum based chemotherapy and had no complications related to the large adrenal masses (
intratumoral hemorrhage or
adrenal insufficiency ) either at presentation or subsequently during treatment and follow up . -
pubmed
enterica serovar 4,[5],12 : i:- is considered to be a monophasic variant of
Salmonella Typhimurium and is increasingly associated with
human infections . -
pubmed
A panel of 206
Salmonella strains was used to validate our multiplex real - time PCR against the conventional multiplex PCR recommended by EFSA , i.e. -
pubmed
43
Salmonella strains of serovars other than Typhimurium and 163 routine isolates determined by slide agglutination serotyping to have an incomplete antigenic formula compatible with the
S . - pubmed
Left atrial volume best predicts
recurrence after catheter ablation in
patients with persistent and longstanding persistent
atrial fibrillation . -
pubmed
INTRODUCTION :
Patients with persistent and longstanding persistent
atrial fibrillation (
AF ) have a higher
recurrence rate after antral pulmonary vein isolation ( PVI ) . -
pubmed
We sought to determine the clinical , invasive , and noninvasive diastolic function parameters that are associated with
AF recurrence after ablation in
patients with persistent and longstanding persistent
nonvalvular AF . -
pubmed
METHODS AND RESULTS : We studied 125 consecutive
patients with persistent and longstanding persistent
AF who underwent antral PVI at our institution between April 2009 and April 2011 . -
pubmed
Ablation eliminated
AF in 83 of 125 ( 66.4 % )
patients ( mean age 61.3 + - 8.9 , 81 % male ) during 17.8 + - 7.7 months of follow - up . -
pubmed
CONCLUSION : Indexed minimal LA volume is highly associated with ablation success in
patients with persistent and longstanding persistent
AF . -
pubmed
METHODS : A total of 265
patients aged 45 years or older admitted with low - energy or high - energy
fractures were reviewed between January 2010 and May 2011 . -
pubmed
RESULTS : Of the 265
patients ( 175 female , 90 male ) , 259 ( 97.7 % )
patients had
low - energy fractures and 6 ( 2.3 % ) suffered high - energy
fractures . -
pubmed
Bone mineral density testing was significantly higher in low - energy
fracture patients who were treated by a young orthopedist , a common
fracture site ( proximal - femur , distal - radius , vertebrae ) or were female ( p<0.05 ) . -
pubmed
In the Old World ,
CL is usually caused by
Leishmania major ,
Leishmania tropica , and
Leishmania aethiopica complex which 90 % of cases occurring in Afghanistan , Algeria , Iran , Iraq , Saudi Arabia , Syria , Brazil , and Peru . -
pubmed
Recently , some reports showed that some
strains of
L. - pubmed
Evidence from the metastatic setting suggests that replacing conventional
doxorubicin with nonpegylated liposomal
doxorubicin (
NPLD ) for early
breast cancer may maintain efficacy whilst reducing long - term
cardiotoxicity , an important consideration with many
patients going on to receive multiple lines of treatment . -
pubmed
Consecutive
patients with early
breast cancer treated with NPLD were assessed for
disease progression and changes in cardiac function according to left ventricular ejection fraction ( LVEF ) . -
pubmed
NPLD appeared to be a well - tolerated substitute for conventional
doxorubicin in
patients with early
breast cancer . -
pubmed
Two thirds of the participating PCPs stated that they routinely provided brief inventions to assist patients in reducing both their
tobacco ( 72 % ) and
alcohol ( 61 % ) consumption , to encourage them to increase their levels of physical activity ( 72 % ) , and to assist them in adjusting to a more healthy diet ( 66 % ) , and in achieving a healthy
body weight ( 69 % ) . -
pubmed
Comparison of restrictive and liberal transfusion strategy on
postoperative delirium in aged
patients following total hip replacement : a preliminary study . -
pubmed
Few studies have examined the association between perioperative blood transfusion and
postoperative delirium ( POD ) in aged
patients undergoing total hip replacement surgery . -
pubmed
Twelve
patients were found with
dysplasia and 13 patients with
IGC , all of them occurred in gallbladders removed for
gallstone diseases . -
pubmed
Median age for
cancer patients was 70 years ( range 51 to 85 ) and 54 years for
dysplasia ( range 18 to 75 ) . -
pubmed
OBJECTIVE : The purpose of this study was to evaluate for the first time the association between 1 - year ablation efficacy and termination mode after repeated catheter ablations in
patients presenting with persistent or long - standing persistent
AF . -
pubmed
METHODS : This prospective study involved 400 consecutive
patients ( age 62.7 + - 7.2 years ) who underwent catheter ablation for drug - refractory persistent
AF ( 4.6 + - 2.4 months ) using a stepwise ablation approach . -
pubmed
RESULTS :
AF was terminated by radiofrequency application directly into SR in 135
patients ; passing through AT into SR in 195
patients ; and through DC cardioversion in 70
patients . -
pubmed
Research on the efficiency of assistive techniques in phoniatric rehabilitation of
patients with unilateral
vocal cord paresis yields conflicting results . -
pubmed
METHODS : Twenty - four
patients ( 17
boys ) who had undergone cranial vault remodeling due to
scaphocephaly were compared from 3D - CT imaging datasets . -
pubmed
Prevalence of
renal insufficiency in hospitalised
patients with
venous thromboembolic events : a retrospective analysis based on 6,725
VTE patients . -
pubmed
Renal function could be determined for 5,710
VTE patients . -
pubmed
Of these 21.4 % had an eGFR>90 mL / min , 38.1 % had an
eGFR of 60 - 89 mL / min , 17.3 % had an
eGFR of 45 - 59 mL / min , 12.5 % had an
eGFR of 30 - 44 mL / min , 7.2 % had an
eGFR of 15 - 29 mL / min and 3.6 % of the
VTE patients had
end - stage renal disease . -
pubmed
Persistent severe
RI was observed in 74.8 % of
patients with an
eGFR & lt;30 mL / min . -
pubmed
Overall , 40.6 % of the
VTE patients investigated had an
eGFR & lt;60 mL / min ; 10.8 % had an
eGFR & lt;30 mL / min . -
pubmed
Recently ,
tumor - induced changes to the
human EC surface were described that provided a basis for designing efficient EC - based vaccines capable of eliciting immune responses that targeted the
tumor endothelium directly . -
pubmed
Of these , there were radiographic findings suggestive of a
fungal infection in 38
patients ( 83 % ) . -
pubmed
Significant postoperative morbidity attributed to biopsy occurred in 3 of 31
patients ( 10 % ) ; 2 patients had
pneumothorax requiring chest tube and intubation and a patient had prolonged intubation . -
pubmed
Optogenetic activation of contralateral PL excitatory neurons exerts analgesic and anxiolytic effects in
mice subjected to chronic
pain , whereas inhibition is anxiogenic in naive
mice . -
pubmed
Does
Staphylococcus aureus have a role in the development of
Type 2 diabetes mellitus ? -
pubmed
To improve vaccine
strain selection ,
human serologic testing on vaccination - induced cross - reactivity need be emphasized along with virus antigenic characterization by
ferret model . -
pubmed
METHODS :
Patients aged 65 years and older in the American College of Surgeons National Surgical Quality Improvement Program database who underwent ORIF for FN
fractures or DF
fractures from 2005 to 2012 were identified . -
pubmed
CONCLUSION : Postoperative morbidity and mortality of geriatric
patients who sustain
DF and FN
fractures treated operatively were comparable . -
pubmed
Methotrexate reduces HbA1c concentration but does not produce chronic accumulation of
ZMP in
patients with rheumatoid or
psoriatic arthritis . -
pubmed
OBJECTIVES : The mechanism by which
methotrexate (
MTX ) improves
glucose homeostasis in
patients with rheumatoid (
RA ) and
psoriatic arthritis (
PsA ) remains undetermined . -
pubmed
METHOD :
MTX - naive ,
non - diabetic RA ( n = 16 ) and
PsA ( n = 10 )
patients received uninterrupted
MTX treatment for 6 months . -
pubmed
CONCLUSION : VR represents a motivational and effective alternative to traditional motor rehabilitation for
MS patients . -
pubmed
The results showed that VR programs could be an effective method of
patients with
MS rehabilitation in multiple cognitive and / or motor deficits . -
pubmed
CONCLUSION : Whilst Dara can interfere with the IFE to determine clinical responses the FLC assay can be useful in
patients who have abnormal FLC ratios prior to Dara therapy to determine responses especially in
IgG - kappa Myeloma . -
pubmed
Pairwise comparisons of the nucleotide sequences and the deduced
amino acid sequences revealed that the four Xinjiang
EV - B106 strains had only 80.5 - 80.8 % nucleotide identity and 95.4 - 97.3 %
amino acid identity with the Yunnan
EV - B106 strain , indicating high mutagenicity . -
pubmed
These four
strains may share a donor sequence with the
EV - B85 strain , which circulated in Xinjiang in 2011 , indicating extensive genetic exchanges between these
strains . -
pubmed
All Xinjiang
EV - B106 strains were temperature - sensitive . -
pubmed
[ Interrelation of Electrophysiological and Perfusion Changes in
Patients With
Left Ventricular Aneurysm ] . -
pubmed
The study was aimed at identification of relations between perfusion and electrophysiological changes in left ventricular ( LV ) myocardium in
patients with
ischemic heart disease (
IHD ) with postinfarction LV
aneurysm and
ventricular tachycardia . -
pubmed
Peri - interventional neurological complication rates in
patients undergoing carotid artery stenting depend on the side of the
stenosis treated . -
pubmed
We investigated if the side of the
stenosis treated has an influence on the neurological outcome of our
patients . -
pubmed
Data of both
patient groups were analyzed with respect to the total rate of peri - interventional
ischemic cerebral events , defined as
transient ischemic attacks , minor and major
strokes , respectively . -
pubmed
BACKGROUND :
Infections greatly influence the outcome of
acute myeloid leukemia (
AML )
patients receiving intensive treatment . -
pubmed
Effect of Antidepressant Switching vs Augmentation on Remission Among
Patients With Major
Depressive Disorder Unresponsive to Antidepressant Treatment : The VAST - D Randomized Clinical Trial . -
pubmed
Importance : Less than one - third of
patients with
major depressive disorder (
MDD ) achieve remission with their first antidepressant . -
pubmed
Design , Setting , and Participants : From December 2012 to May 2015 , 1522
patients at 35 US Veterans Health Administration medical centers who were diagnosed with
nonpsychotic MDD , unresponsive to at least 1 antidepressant course meeting minimal standards for treatment dose and duration , participated in the study . -
pubmed
Abnormal results were only found in 6/51 ( 12 % )
patients with MRI and 12/51 ( 24 % )
patients with
HRUS . -
pubmed
CONCLUSIONS : Brachial plexus sonography could complement MRI in the diagnostic work - up of
patients with suspected
CIDP and MMN . -
pubmed
METHODS : Prospective cohort of 171
participants ( mean age 61 years ;
BMI 32 kg / m2 , 71 % female ; 57 % white ) with symptomatic
knee OA from a randomized trial comparing 12 - week Tai Chi and Physical Therapy . -
pubmed
Materials and methods : The aim of this study was to describe the diagnostic and treating modalities applied in nine
patients with
CD and
EVFs , the clinical / epidemiological features of this clinical entity and to perform a systemic review of the literature , concerning the diagnosis and treatment of this complication . -
pubmed
Mean
patient reported KOOS activities of daily living and
pain scores were each 90 . -
pubmed
The aim of this retrospective study was to investigate the prognostic significance of pre - treatment immunological and nutritional statuses in
patients with locally advanced
gastric cancer (
GC ) , and to use the risk factors to develop a predictive score . -
pubmed
Background : The objective of this study was to compare the clinical and radiological outcomes between
patients with or without axial symptoms (
AS ) and investigate the risk factors associated with
AS by multivariate regression analysis in anterior cervical discectomy and fusion ( ACDF ) . -
pubmed
Results : The
patients were divided into two groups : one with
AS (
AS group , n=35 ) and the other without ( NAS group , n=82 ) . -
pubmed
Conclusion :
AS do not correlate with recovery of neural function in
patients treated by ACDF . -
pubmed
The ability of resynchronization to improve LVEF without GDMT suggests that CRT without waiting 3 months for GDMT optimization may benefit some
patients with
NICM and
LBBB . -
pubmed
This method provides a novel approach for
human intestinal regeneration and can be used to identify potential
cancer driver genes . -
pubmed
Aims : We sought to examine whether
disturbances in central and peripheral circadian rhythms were related to the experience of
fatigue in
patients with
chronic liver disease (
CLD ) . -
pubmed
Methods : Fatigued and non - fatigued
patients with compensated
CLD were enrolled in a prospective pilot study . -
pubmed
Results : Six fatigued and six non - fatigued
patients were studied ; five participants had
cirrhosis . -
pubmed
Fatigued
patients showed a blunted and delayed
cortisol rhythm and
fatigue was strongly correlated with
cortisol amplitude ( rho=-0.77 , p=0.004 ) and phase ( r=-0.66 , p=0.02 ) . -
pubmed
Conclusion : Subtle aberrations in
melatonin and adrenal circadian rhythms , as well as
reduced sleep efficiency , likely contribute to
fatigue in
patients with
CLD . -
pubmed
These abnormalities may ultimately be a therapeutic target to improve quality of life for fatigued
patients with
CLD . -
pubmed
This case of endograft explantation is of even greater complexity , given the
patient 's specific history of
aneurysm repair in the concomitant setting of a functioning renal allograft . -
pubmed
Advanced imaging modalities provide essential anatomic and spatial information in
patients with complex
heart disease . -
pubmed
Many groups have reported the use of 3D printing for preprocedural planning in
patients with different causes of
heart failure . -
pubmed
High expression of both proteins identified a poor prognosis subgroup in
patients with locally advanced
HNSCC after RCTx . -
pubmed
MATERIALS AND METHODS : This was a retrospective study of
patients with suspected
SpA referred from the rheumatology department of a university teaching hospital undergoing MRI both of the whole spine and of the sacroiliac joints over a 3 - year period . -
pubmed
RESULTS : Three hundred and sixty - five
patients with suspected
SpA undergoing both whole spine and sacroiliac joint MRI were identified . -
pubmed
METHODS : A total of 108
patients who presented with
parotid duct stenoses ( 130 parotid glands ) were examined with high - resolution US between 2014 and 2017 . -
pubmed
Materials and Methods : Fifty - one
children with
ASD ( five females and 46 males ) aged 7 - 12 participated in the study . -
pubmed
Therefore , to explore the mechanism of
DEHP - induced
splenic toxicity ,
male quail were employed with 0 , 250 , 500 and 750 mg / kg
body weight DEHP by daily gastric perfusion for 45 days . -
pubmed
CASE REPORT We present the case of a 48 - year - old
male with a personal history of
mediastinal Hodgkin lymphoma who was treated with local radiotherapy 20 years ago , and who was admitted to hospital due to
dyspnea and oppressive
chest pain with efforts . -
pubmed
This fact is very relevant , and this report can help determine the aspects of radiotherapy - induced
heart disease affecting the mortality and morbidity of these
patients . -
pubmed
We recruited 48
patients carrying a known or suspected
liver disease to undergo
gadoxetic acid - enhanced MR imaging . -
pubmed
CASE PRESENTATION : A 3 - month - old female
patient with the correctable type of
biliary atresia underwent a cystoduodenostomy . -
pubmed
CONCLUSIONS :
Cholangiocarcinoma is extremely rare in
patients with
biliary atresia . -
pubmed
However , physicians should follow up
patients with
biliary atresia as closely as possible , as
malignant tumors secondary to
biliary atresia may increase in number in the near future because of the growing number of long - term survivors with
biliary atresia . -
pubmed
Vaccine - enhanced disease (
VED ) occurs as a result of vaccination followed by
infection with virulent
Mycoplasma pneumoniae . -
pubmed
To date
VED has prevented development of an efficacious vaccine against this significant
human respiratory pathogen . -
pubmed
Preliminary detection of
lung hypoperfusion in discharged Covid-19
patients during recovery . -
pubmed
Patients with
pulmonary arterial hypertension or
chronic thromboembolic pulmonary hypertension are at risk of developing
sleep - related breathing disorders . -
pubmed
There should be a strong suspicion of
sleep - related breathing disorders in such a
patient population , however the precise indications for sleep studies and the type of recording remain to be specified . -
pubmed
The diagnosis of
obstructive sleep apnoea syndrome in
patients with
pulmonary arterial hypertension or
chronic thromboembolic pulmonary hypertension should encourage treatment with continuous positive airway pressure . -
pubmed
However , it is prudent not to treat central
apnoea and Cheynes - Stokes respiration with adaptive servo - ventilation in
patients with chronic right
heart failure because of a potential risk of serious adverse effects from such treatment . -
pubmed
In this review we will consider the current knowledge of the consequences of
sleep - related breathing disorders on pulmonary haemodynamics in
patients with and without chronic
respiratory disease ( group 3 of the clinical classification of
pulmonary hypertension ) and the effect of treatments of respiratory events during sleep on
pulmonary hypertension . -
pubmed
Does dietary
nitrate supplementation with
beetroot juice attenuate thermoregulatory and cardiovascular
strain in older adults during severe heat stress ? -
pubmed
These data suggest
nitrate supplementation with
beetroot juice does not mitigate thermoregulatory or cardiovascular
strain in heat - stressed older individuals . -
pubmed
ABSTRACT : This study tested the hypothesis that dietary
nitrate supplementation with concentrated
beetroot juice attenuates thermoregulatory and cardiovascular
strain in older individuals during environmental heat stress . -
pubmed
Overall , these findings suggest that dietary
nitrate supplementation with concentrated
beetroot juice does not attenuate thermoregulatory or cardiovascular
strain in older individuals exposed to severe ambient heat stress . -
pubmed
MATERIALS AND METHODS : In this prospective study , a group of 567
patients with
OSF were enrolled from 1986 to 2017 and followed - up until 2019 . -
pubmed
We analyzed the betel quid chewing habits and found all 32
patients with
OSCC - chewed betel quid . -
pubmed
The
OSCC was located in the left or right buccal regions in 23
patients ( 23/32 ; 72 % ) and in the left or right lingual regions in 4
patients ( 4/32 ; 12 % ) . -
pubmed
Well , moderately and poorly differentiated
squamous cell carcinoma was present in 23
patients ( 23/32 ; 72 % ) , 4
patients ( 3/32 ; 9 % ) , and 5
patients ( 5/32 ; 16 % ) , respectively . -
pubmed
CLINICAL RELEVANCE : The long duration of the transformation from the
OSF to
OSCC suggests more frequent examinations and corresponding treatments are necessary for
OSF patients . -
pubmed
Introduction and switching of biologic agents are associated with antidepressant and anxiolytic medication use : data on 42 815 real - world
patients with
inflammatory rheumatic disease . -
pubmed
In conclusion , m6A RNA methylation regulators are closely correlated with CESC clinical characteristics andtheselected 6 m6A RNA methylation regulators may be useful for
CESC patients personalized treatment . -
pubmed
Objectives : Blood bank centers routinely screen for
hepatitis B virus (
HBV ) ,
hepatitis C virus (
HCV ) , and
human immunodeficiency virus (
HIV ) to ensure the safety of blood supply and thus prevent the dissemination of these viruses via blood transfusion . -
pubmed
Bone diseases such as
osteomalacia ,
osteoporosis , and
osteomyelitis are major illnesses that threaten the health of
human . -
pubmed
BACKGROUND : Lumbar X - rays are usually preferred in
patients with
lower back pain , but
lumbar spinal stenosis (
LSS ) can not be directly observed on lumbar X - ray films . -
pubmed
A group of 25
patients with
non - Hodgkin ' s lymphoma was investigated . -
pubmed
The presence of growth lines in the distal radius was evaluated prior to treatment in 23 psychosocial dwarfs and 25
patients with
idiopathic hypopituitarism . -
pubmed
Short - term and serial memory in
autistic , retarded , and normal
children . -
pubmed
No differences were found among groups in rate of learning , although the
autistic children improved significantly on the second and longer series . -
pubmed
The results are interpreted as supporting the view that when
MA and response acquisition level are equated with normal and retarded
children in a memory task ,
autistic children do not show any specific
memory deficits . -
pubmed
Enzootic with
ectromelia symptomatology in
Sprague - Dowley rats . -
pubmed
[ Immunoenzymatic diagnosis ( ELISA ) of
human African
trypanosomiasis . -
pubmed
A comparative study , by ELISA , of purified exoantigen and of five crude antigenic extracts from several
strains of
T.b . - pubmed
After 13 doses of Ep ( 5 u / dose ) , started either 5 or 21 d after removal of five - sixths of the renal mass , the increase in the red cell volume of
uraemic rats was as great as that of non - uraemic ones . -
pubmed
The
individual developing unilateral
adrenocortical carcinoma showed rapid adrenal expansion ,
feminization , and an abnormal urinary
steroid profile after 4 yr of observation for bilateral minor adrenal enlargements . -
pubmed
RESULTS :
MAI occurred in 8 % of those
patients with 1 - day therapy and 10 % with 5 - day therapy . -
pubmed
Arthroscopic surgery for
osteochondritis dissecans of the femoropatellar joint of the
horse . -
pubmed
Arthroscopic surgery for the treatment of
osteochondritis dissecans was undertaken on 252 femoropatellar joints in 161
horses ( 82 Thoroughbreds , 39 Quarter
Horses , 16 Arabians , 9 Warmbloods and 15 others of various breeds ) . -
pubmed
Horses with Grade I lesions ( & lt ; 2 cm in length ) had a significantly higher success rate ( 78 % ) than did
horses with Grade 2 ( 2 - 4 cm ) or Grade 3 ( & gt ; 4 cm )
lesions ( 63 % and 54 % success rates respectively ) . -
pubmed
Intensive
strain of racing - horses during training and race is not an end in itself but should be understood from the social task to create exceptionally efficient
horses . -
pubmed
[ The effect of hemodialysis on neutrophil enzyme activity in
patients with
uremia ] . -
pubmed
Basing on measurements of the activities of 7 lysosomal enzymes , the authors have assessed the enzymic activities of neutrophils in 22
patients with protracted
renal insufficiency treated by hemodialysis . -
pubmed
[ Doppler echocardiography in the evaluation of hemodynamics in
children with bilateral forms of chronic nonspecific
inflammatory lung diseases ] . -
pubmed
In this work 26
patients with schistosomal specific
nephropathy were randomly distributed among three groups . -
pubmed
Patients who had another etiologic cause which may explain their
kidney disease were not admitted to this study . -
pubmed
We conclude that in
patients with
schistosomal nephropathy , none of the tried therapeutic regimens produce regression of the disease if given to
patients with established disease . -
pubmed
One hundred and sixteen
patients with
cervical intraepithelial neoplasia were treated by
CO2 laser excisional conization , from 1985 to 1987 . -
pubmed
3 ) In our series , 10.3 % ( 6 out of 58 ) of the
women with
dysplasia or
CIS (
surgical margin negative ) required two treatments respectively to eradicate their disease from 9 months to 16 months after laser conization . -
pubmed
4 ) None of 72
women developed
postoperative cervical stenosis and
cervical infection . -
pubmed
A total of 24 pregnant
women with
growth - retarded fetuses were studied to examine the distribution of fetal heart rate accelerations between 30 and 40 weeks ' gestation , as compared with those of fetuses of normal growth that were matched for gestational age and length of fetal heart rate tracings . -
pubmed
Proctoscopically diagnosed third - degree
haemorrhoids were treated with rubber band ligation ( RBL ) in 92
patients , who were randomly assigned to management with or without twice - daily intake of unprocessed bran for 18 months . -
pubmed
A high - fiber diet thus increased the long - term cure rate among
patients with third - degree
haemorrhoids initially cured by RBL . -
pubmed
[ Epidemiologic study of spontaneous
mesothelioma in
dogs : its possible usefulness in reference to
human pathology ] . -
pubmed
Two of these patients developed their
hydrocephalus after
intraventricular hemorrhage , and in six
patients the
hydrocephalus was associated with
myelodysplasia . -
pubmed
This is followed by a description of the exocrine pancreatic function in
type I diabetes of
humans and in experimental
insulin deficiency diabetes of
rats . -
pubmed
Of the 52
patients who died during the follow - up period ,
hepatocellular carcinoma was the cause of
death in 3 ( 33 % ) of the 9 men , and 2 ( 5 % ) of the 43 women . -
pubmed
In 2 series of 10
patients , each unilateral laser iridotomy was performed with a YAG - laser prior to
cataract surgery . -
pubmed
In catheterized
rats recovery of liver and
body weight lagged behind that of non - catheterized
rats . -
pubmed
Flavobacterium and Alcaligenes have been implicated in shell egg rots ,
Staphylococcus aureus has been implicated in
food poisoning , and organisms resembling micrococci and actinomycetes have been found in broken - out egg products . -
pubmed
We conclude that when third - trimester normoglycemia is maintained in pregnant
diabetic patients , one obviates the need for the costly and odious task of daily urine
estriol measurements . -
pubmed
[ Functional morphology of the myocardium and carotid paraganglion of
dogs during electrical stimulation of the carotid
sinus nerve in experimental
stenocardia ] . -
pubmed
6
patients with
thrombocytopenia and
anaemia had
fatty marrow replacement at the site of an iliac crest . -
pubmed
The pelvic and sternal marrow cellularity in
patients with
pancytopenia may not be representative of the cellularity of the whole marrow , and the pelvic marrow especially may be prone to
aplasia . -
pubmed
The
infection rate in
chickens increased from 23 % in those weighing less than 500 g , to 73 % in those between 500 and 1,000 g , indicating a rapid rate of acquiring infectin , probably from the soil in which they constantly search for food . -
pubmed
Most
strains of Toxoplasma isolated from
Costa Rican cats produced
chronic latent infections in
mice . -
pubmed
However , even when infected with virulent
strains ,
mice died at a time when numerous bradyzoites had been formed . -
pubmed
The value of the Hertel measurement evaluated by a group of
patients with
thyroid diseases and a control group ] . -
pubmed
Exophthalmometry values from routine referrals to a hospital eye clinic are analysed , including adult
patients with and without
thyroid disease . -
pubmed
Thyroid
patients with eye muscle involvement (
diplopia , n = 47 ) had significantly higher values ( median 22 mm , range 15 - 31 mm ) but did not differ significantly from a subgroup of 51
patients without
thyroid disease , but with " big eyes " as a ( presumably ) physiological finding ( median value 20 mm , range 16 - 25 mm ) . -
pubmed
Seven of the
patients with left sided
tumors had an average 1314 sq mm heart irradiated in the central axis . -
pubmed
Because of the reduction in invasiveness that arthroscopy provides , outpatient surgery is now routinely employed for
ACL patients . -
pubmed
The time to total relief of
diarrhea and of all symptoms was also significantly shorter in
fleroxacin - treated
patients . -
pubmed
Harmaline - induced
impairment of Pavlovian conditioning in the
rabbit . -
pubmed
Body weight , crown - rump length , and limb length measurements , synchronized to pubertal onset , suggest that a pubertal growth spurt occurs in male
baboons . -
pubmed
METHODS : Between 1964 and 1994 40
patients , ranging from 14 months to 52 years old , underwent an operative approach designed to minimize
trauma to the sinus node and its blood supply . -
pubmed
The anomalous pulmonary veins were redirected across a
sinus venosus
atrial septal defect ( 33
patients ) or a surgically created
atrial septal defect ( 7
patients ) into the left atrium . -
pubmed
The
atrial septal defect rim was coapted to the intracardiac SVC orifice in 23
patients . -
pubmed
RESULTS : One 31 - year - old
woman died of severe
pulmonary hypertension . -
pubmed
All
patients remained well over follow - up ( 6 months to 30 years ) , without residual
intracardiac defects . -
pubmed
Sick sinus syndrome developed late in only 1
patient ( 2.5 % ) . -
pubmed
Membrane attack complex in thickened cutaneous sensory nerves of
leprosy patients . -
pubmed
Therefore , an attempt was made to demonstrate MAC in peripheral nerve biopsies , collected from
leprosy patients . -
pubmed
Interestingly , we could demonstrate deposition of
MAC in involved cutaneous sensory nerves from most of the
lepromatous leprosy patients . -
pubmed
Recurrent
cancer has developed in 4 of the 18
patients ( 22 % ) . -
pubmed
The site of first
recurrence was the lung in three
patients ( 17 % ) and the pelvis in one ( 6 % ) ; no
patients recurred in the liver . -
pubmed
Seventy
dementia patients in hospital and two control groups comprising 50
dementia sufferers in the community and 50 mentally fit elderly people , were investigated to determine which social factors such as life events were associated with the presence of
anxiety symptoms . -
pubmed
We report a prospective study of thirty four therapeutic temporomandibular arthroscopies that were done during a 24 months period for
patients with
debilitating joint disorders ( mainly disc displacements with or without reduction ) who had not responded to no - invasive treatment . -
pubmed
Previous results have documented a burst of IL-4 mRNA that peaks in draining lymph nodes of susceptible BALB / c
mice 16 h after
infection with Leishmania major . -
pubmed
The severity of
congestive heart failure in 31
patients with
congenital heart disease was graded by a scoring system which included a description of historical and clinical variables . -
pubmed
Patients were divided into a group with no or mild
heart failure ( score & lt ; or = 6 ) and a group with severe
heart failure ( score & gt ; 6 ) . -
pubmed
Efficacy of orchidopexy on spermatogenesis in the immature mutant ' trans - scrotal '
rat as a
cryptorchid model by quantitative cytological analysis . -
pubmed
OBJECTIVES : To determine whether
cryptorchidism is a
congenital malformation and whether the impaired spermatogenesis in immature testes can be reversed by early orchidopexy , using the mutant trans - scrotal ( T - S )
rat which is normally masculinized but has
cryptorchidism in 85 % of males . -
pubmed
1 , with normally descending testes ( normal control , 10
rats ) ; 2 , with
undescended testes ( UDT ) treated by orchidopexy ( treated UDT , eight
rats ) ; 3 , with UDT treated by a sham operation ( sham - operated UDT , six
rats ) ; and 4 , with UDT left untreated ( untreated UDT , six
rats ) . -
pubmed
CONCLUSIONS : These results show that in the T - S
rat with
cryptorchidism , the
testicular damage is not a
congenital malformation and can be reversed with early surgical correction . -
pubmed
Fractures of the neck or the pertrochanteric region are often treated with dynamic hip screw especially in elderly
patients . -
pubmed
We give a case report covering treatment and follow - up for a bilateral spontaneous
pertrochanteric fracture in a 45 - year - old
man as a result of hepatogenetic
osteopathy . -
pubmed
Efficacy of
pentoxifylline with
aspirin in the treatment of
frostbite in
rats . -
pubmed
The efficacy of
pentoxifylline -- a haemorrheologic agent along with
aspirin -- an analgesic agent was evaluated in the amelioration of the
tissue damage due to experimentally induced
frostbite in 5 groups ( 20 each ) of
rats with
body weights ranging between 175 and 200 g.
Frostbite was produced experimentally in the hind limbs by exposing the
animals to -15 + /- 1 degrees C for 1 h using the harness technique , with simultaneous recording of rectal and environmental temperatures . -
pubmed
The combined pharmacological properties of these two drugs might have altered the haemorrheologic status of blood and produced the curative beneficial effect in improving tissue survival following experimentally induced
frostbite in
rats . -
pubmed
PATIENTS AND METHODS : One hundred and seven chronic
urticaria patients were studied . -
pubmed
Concomitant diseases suggesting
autoimmune reactivity were detected in nine
patients and , in 16
patients ,
infections including
maxillary sinusitis ,
streptococcal tonsillitis , and
tooth infection were found . -
pubmed
INTRODUCTION : There have been only a few studies on differentiated childhood
thyroid cancer (
DTC ) in
children and adolescents . -
pubmed
METHODS : We analyzed the characteristics of
DTC with respect to age , gender and histology in 114
patients under 18 years of age . -
pubmed
Characteristics of 80
females and 34 males were evaluated , and the prognostic effect of age , gender , histology , multicentric growth ,
tumor stage and N - status on distant
metastases was tested using multivariate discriminant analysis . -
pubmed
RESULTS : The incidence of
DTC in females was higher than in males with a peak of female : male ratio at puberty , which was more pronounced in
children with
papillary thyroid cancer , but not with
follicular thyroid cancer . -
pubmed
Determinants of bone mass in
systemic lupus erythematosus : a cross sectional study on premenopausal
women . -
pubmed
Osteoporosis was defined as a t score below 2.5 SD compared to a reference population of healthy
women in at least one region of measurement . -
pubmed
Osteoporosis was detected in 22.6 % of
patients . -
pubmed
Compared with non - osteoporotic
patients with
SLE , women with
osteoporosis had similar age , lower
body mass index , significantly longer disease duration ( p & lt ; 0.0001 ) , higher cumulative
steroid intake ( p & lt ; 0.006 ) , and higher SLICC / ACR score ( p & lt ; 0.01 ) . -
pubmed
CONCLUSION :
Osteoporosis is a frequent feature in young
patients with
SLE . -
pubmed
These parameters were also measured in healthy donors and in
cancer patients at the time of the diagnosis and following the administration of high doses of cytotoxic drugs requiring stem cell support . -
pubmed
OBJECTIVE : To determine the endometrial effects of
raloxifene 60 mg / day in postmenopausal
women as assessed by
vaginal bleeding and endometrial thickness . -
pubmed
RESULTS :
Raloxifene 60 mg / day was not significantly different from placebo with regard to the incidence of
vaginal bleeding , the baseline - to - endpoint change in endometrial thickness , or the proportion of
women experiencing an increase in endometrial thickness above baseline after either 12 or 24 months of therapy . -
pubmed
CONCLUSION :
Raloxifene 60 mg / day for up to 30 months is not associated with
vaginal bleeding or increased endometrial thickness in postmenopausal
women . -
pubmed
Targeted disruption of
murine Cryptic results in
L - R laterality defects including randomization of
abdominal situs ,
hyposplenia , and pulmonary right isomerism , as well as randomized embryo turning and cardiac looping . -
pubmed
Our sample was comprised of 51
patients with late - life
MDD and 30 non - depressed controls . -
pubmed
Patients with
MDD had significantly smaller frontal lobe volumes , together with larger whole brain lesion volumes when compared with controls ( p & lt ; .05 ) . -
pubmed
BACKGROUND AND OBJECTIVE : Noninvasive diagnosis of intestinal
necrosis is important in planning surgery in preterm
infants with
necrotizing enterocolitis (
NEC ) . -
pubmed
STUDY PARTICIPANTS AND METHODS : Abdominal MRI scans were performed in a group of preterm
infants with suspected
NEC and compared with surgical findings and to MRI results in a group of control infants . -
pubmed
In addition , MRI was performed in 2 preterm
infants with suspected
NEC who did not require surgery . -
pubmed
RESULTS : Six
infants with a median
birth weight of 1220 g ( range , 760 - 1770 g ) and median gestational age at birth of 30 weeks ( range , 28 - 34 weeks ) were studied at a median postnatal age of 10 days ( range , 4 - 19 days ) . -
pubmed
This may aid the timing of surgical intervention in preterm
infants with a clinical diagnosis of
NEC.gangrene ,
ischemia , MRI ,
necrotizing enterocolitis . -
pubmed
PATIENTS : Forty - two
patients underwent surgery for
liver hemangiomas between January 1988 and December 1998 ; 41 were symptomatic . -
pubmed
The primary indications for surgery were
abdominal pain in 33
patients , diagnostic uncertainty in 6 , and enlargement in 3 . -
pubmed
MAIN OUTCOME MEASURES : ( 1 )
Patients ' assessment of the effects of surgery on preoperative symptoms , ( 2 ) determination of whether any other pathological conditions were missed in the preoperative evaluation , ( 3 ) operative mortality and morbidity , and ( 4 )
recurrences . -
pubmed
Hospital mortality and morbidity were 2.4 % (
bleeding from the biopsy site on a lesion evaluated as inoperable at laparotomy ; 1
patient ) and 12 % ( 5
patients ) , respectively . -
pubmed
No other cause of
pain could be identified during follow - up in the other
patients . -
pubmed
CONCLUSIONS : Elective surgery is indicated in a small subset of
patients with
hemangiomas because of
abdominal pain , enlargement , and diagnostic uncertainty . -
pubmed
This result indicated that the previously reported inhibition of
type 1 diabetes in NOD
mice carrying a functionally inactivated IFN - gamma receptor alpha - chain gene may have been due to a closely linked and previously unidentified
diabetes resistance allele . -
pubmed
We describe a 19 - year - old
woman with
fulminant hepatic failure due to
acute hepatitis B infection who received a living donor liver transplant from her sister . -
pubmed
Is the
human papillomavirus DNA present in
penile warts ? -
pubmed
Infection with human papillomavirus (
HPV ) has been established to be a
sexually transmitted disease , with a potential risk of intraepithelial
neoplasia and
invasive cancer , function of the genotype involved . -
pubmed
Scraped cells from
lesions of 27 men establishing various types of
penile warts were investigated by PCR for
HPV DNA detection . -
pubmed
2
HPV6 and 7
HPV ND infections were determined . -
pubmed
The findings in this study confirmed the
HPV involvement in
penile warts . -
pubmed
PURPOSE : To report the clinical findings and surgical treatment of multifocal , bilateral
orbital hemangiomas in a
patient with the
blue rubber bleb nevus syndrome , a rare
vascular disorder characterized by distinctive
cutaneous and visceral hemangiomas . -
pubmed
RESULTS : A 36 - year - old
female with multifocal , bilateral
orbital lesions was seen with severe
proptosis and
decreased visual acuity of the left eye . -
pubmed
[
Tobacco brand - related
headache ] . -
pubmed
INTRODUCTION :
Tobacco smoking has been considered a risk factor for
headache by some authors , while others disagree because of contradictory data . -
pubmed
PATIENTS AND RESULTS : We describe the clinical aspects of eleven
patients ( four
men and seven
women ) who presented to us with
tobacco brand - related
headaches . -
pubmed
More studies will be necessary in order to discover the mechanism leading patients to
tobacco brand - related
headache . -
pubmed
Dilatation of the cystic duct in
patients with
obstructive jaundice . -
pubmed
BACKGROUND : It is well known that
obstructive jaundice causes biliary dilatation , but sonographic ( US ) findings of the cystic duct in
patients with
obstructive jaundice are rarely reported . -
pubmed
We addressed this issue in 51 abstinent
patients with histories of severe
chronic alcoholism utilizing the Minnesota Multiphasic Personality Inventory ( MMPI ) and the Halstead - Reitan Neuropsychological Test Battery ( HRNTB ) . -
pubmed
One hundred seventy - four
patients underwent surgery for perforated
peptic ulcer . -
pubmed
Levetiracetam is a new anti -
epileptic drug that is currently not licensed for use in
children . -
pubmed
Studies in
adults suggest that it may be a useful adjunctive treatment both in partial onset and generalised
epilepsy . -
pubmed
A retrospective case notes review of 26
children age 10 years and under with
refractory epilepsy was undertaken to evaluate the efficacy and safety of the drug . -
pubmed
The drug appeared to be most effective in
children with partial onset
seizures and least effective in those with
myoclonic seizures . -
pubmed
Sixty - one percent of
patients showed a good response to
levetiracetam with at least a 50 % reduction in
seizure frequency with two of these 26
children with previously refractory
epilepsy becoming
seizure - free . -
pubmed
We evaluated the clinical signs and treatment of 16
patients with
postpolio syndrome . -
pubmed
Surgery can alleviate many of the distressing symptoms in
patients with metastatic
colorectal carcinoma . -
pubmed
Effect of
Helicobacter pylori eradication on anti -
thrombotic dose
aspirin - induced
gastroduodenal mucosal injury . -
pubmed
BACKGROUND :
Helicobacter pylori infection and non - steroidal anti - inflammatory drugs are two major causes of
gastric injury but the effect of
H. - pubmed
The aim of the present study was to investigate the effect of
Helicobacter pylori eradication on
gastroduodenal mucosal injury induced by antithrombotic doses of
aspirin . -
pubmed
CONCLUSION :
Helicobacter pylori eradication may prevent medium - dose
aspirin - induced
gastroduodenal mucosal injury . -
pubmed
BACKGROUND : We sought to investigate the incidence and risk of
embolism after percutaneous balloon mitral commissurotomy ( PMC ) and delineated the necessity of the maze procedure in
patients with
atrial fibrillation (
AF ) . -
pubmed
Next our current criteria for indication of the maze procedure , which included duration of
AF less than 10 years , voltage of f wave on electrocardiography greater than 0.1 mV , cardiothoracic ratio less than 70 % , and left atrial dimension less than 70 mm , were applied to all
patients . -
pubmed
RESULTS : Thirty - eight
patients suffered from
embolic complications after PMC . -
pubmed
Of these 33
patients experienced
AF before intervention . -
pubmed
The actuarial
embolism - free rate at 10 years was 81.9 % in
patients with
AF before PMC and 92.9 % in
patients with
sinus rhythm before PMC ( p = 0.01 ) . -
pubmed
In a comparative study of the selected
patients the actuarial
AF - free rates after MVS / maze were 89.9 % at 1 year and 85.7 % at 5 years and were significantly higher than those of 17.3 % at 1 year and 4.2 % at 5 years after PMC ( p & lt ; 0.0001 ) . -
pubmed
Surgical treatment concomitant with the maze procedure may be beneficial for
patients with
AF . -
pubmed
Patients with
migraine with and without aura as classified by the International
Headache Society were recruited to a double - blind placebo - controlled crossover study . -
pubmed
Patients were instructed to treat two attacks of at least moderate
pain severity , with at least a 7 day interval , using subcutaneous 100 microg
octreotide or matching placebo . -
pubmed
Modelling the
headache response as a binomial determined by treatment , using the
patient as the level 2 variable , and considering a possible period effect , and sex and
migraine type as other variables of interest , subcutaneous
octreotide was not significantly superior to placebo . -
pubmed
At a certain point in development , axons in the
mammalian CNS undergo a profound loss of intrinsic growth capacity , which leads to poor regeneration after
injury . -
pubmed
Their involvement in the pathogenesis of
chronic arthritis is controversial , however , and so we examined their role in experimental antigen - induced
arthritis in
mice . -
pubmed
Transfer of CD4+CD25 + cells into immunized
mice at the time of induction of antigen - induced
arthritis decreased the severity of disease but was not able to cure established
arthritis . -
pubmed
Transient attenuation of
neuropathic manifestations in
rats following lesion or reversible block of the lateral thalamic somatosensory nuclei . -
pubmed
BACKGROUND AND AIMS : Nociceptive behavior in
animal models for
mononeuropathy has been shown to be altered by
spinal tract lesions which suggest a possible supraspinal modulation . -
pubmed
METHODS : Different groups of
rats ( n = 5 - 6 ) were subjected to
mononeuropathy , following the spared
nerve injury model , known to produce sustained heat
hyperalgesia and tactile and cold
allodynia which peaked about 2 weeks after
nerve injury . -
pubmed
Oxidative stress in
Helicobacter pylori - induced
gastric cell injury . -
pubmed
Helicobacter pylori induces decrease in antioxidant defense factors , such as
GSH , mucus and constitutive
nitric oxide (
NO ) ,
gastric mucosal injury and
inflammation . -
pubmed
We tested the efficacy of an FTI (
ABT-100 ) in
Zmpste24 - deficient mice , a
mouse model of
progeria . -
pubmed
The
FTI - treated
mice exhibited improved
body weight , grip strength , bone integrity , and percent survival at 20 weeks of age . -
pubmed
These results suggest that
FTIs may have beneficial effects in
humans with
progeria . -
pubmed
PATIENTS AND METHODS : In this retrospective study , the subjects were 158
patients with
ischemic stroke , including 105 with a normal tHcy level and 53 with a high tHcy level . -
pubmed
Classification of
non - bacterial osteitis : retrospective study of clinical , immunological and genetic aspects in 89
patients . -
pubmed
Patients with sterile
osteitis were analysed to develop diagnostic criteria . -
pubmed
METHODS : A total of 89
patients with non - bacterial
inflammatory bone lesions were observed for a median of 49 months . -
pubmed
Twenty percent of all the
patients demonstrated associated
autoimmune disorders , particularly of the skin and bowel . -
pubmed
Autoimmune diseases in 40 % of all the families , multiply affected family members , linkage to 18q21 and
mouse models strongly indicate a genetic basis for
NBO . -
pubmed
Two
patients with
subclavian vein thrombosis are presented in which a balloon venoplasty led to recanalization of the subclavian vein and complete remission of clinical symptoms . -
pubmed
In
patients with extreme symptoms and unsuccessful initial catheter - directed local thrombolysis , this non - operative approach can be considered despite known favourable spontaneous outcome of
subclavian vein thrombosis . -
pubmed
Fourteen
patients had
squamous cell carcinoma and one
adenocarcinoma . -
pubmed
coli O157 and
non - O157 strains . -
pubmed
The vero cell
cytotoxicity assay detected VT - producing
strains of
E. - pubmed
coli isolates that were VT positive ( vero cell ) or VT - gene positive by PCR , 2.2 % , 2.2 % , 4.4 % and 6.7 % belonged to non -
O157 strains O91 ,
O111 ,
O103 and
O157 , respectively , as determined by the Dry
spot test . -
pubmed
In addition , the demonstration of
VTEC strains in
humans ,
VT gene in faecal samples and
E. - pubmed
coli isolates as well as
non - O157 VTEC strains of
E. - pubmed
The problem of transporting a
patient with
AMI and
cardiogenic shock to a distant site and the problem of emergency CABG in such high - risk
patients is discussed . -
pubmed
We genotyped 272
children with
atopic asthma , 54
children with
nonatopic asthma (
NAA ) , and 254 control children for allelic determinants at two polymorphic sites in the region at positions promoter - 318 C & gt ; T and exon 1 + 49 G & gt ; A using restriction fragment length polymorphism methods . -
pubmed
In the current study , we performed
strain rate , creep , and stress - relaxation experiments using
porcine AVL under planar biaxial stretch and loaded to physiological levels ( 60 N / m equi - biaxial tension ) , with
strain rates ranging from quasi - static to physiologic . -
pubmed
Antifungal treatment was scheduled for
patients suspected clinically , mycologically or cytologically as having
candidal infection . -
pubmed
Two years after the first operation the
patient has no detectable
tumor . -
pubmed
METHODS : GI tract specimens were reviewed ( 221 total ; 93 esophageal , 55 gastric cardiac , 48 oxyntic , 7 antral , 8 small bowel , 6 colonic , 3 appendiceal , 1 anal ) from 71
patients ( 63 M , 8F ) , 38 to 84 years ( median , 55 y ) undergoing chemotherapy for
esophageal , breast , or lung cancer who had all received
taxanes at some time [ either
paclitaxel (
Taxol , 55 patients ) or
docetaxel (
Taxotere , 16
patients ) ] . -
pubmed
RESULTS : Five samples had striking mitotic arrest mimicking
HGD in
non - neoplastic mucosa and were from the esophagus , gastric cardia , gastric body , gastric antrum , and appendix of 5 separate
patients . -
pubmed
On follow - up , in 3/5
patients with samples 1 day posttreatment , 1 had acute
appendicitis ( died 180 d postappendectomy ) , 1 died a day later of
metastases , and 1 was asymptomatic ( alive with metastatic
disease at 126 d postbiopsy ) . -
pubmed
We present here the history of a
patient developing an isolated
pulmonary hypertension related to the intake of
pergolide . -
pubmed
The treatment of acute
respiratory infections in
children with orally administered , unbuffered
penicillin solutions . -
pubmed
A significant proportion of
patients with
myocardial infarction are missed upon initial presentation to the emergency department . -
pubmed
In conclusion , the 15 - lead ECG identified more
patients with posterior
myocardial wall ischemia because of temporary balloon occlusion of the LC than the 12 - lead ECG . -
pubmed
All
patients had associated
renal insufficiency . -
pubmed
Four
patients ( 31 % ) had
infection . -
pubmed
The management of
children with
Hunter syndrome - a case study . -
pubmed
Children with this debilitating disease can now be offered enzyme replacement therapy ( ERT ) with
idursulfase to manage the
signs and symptoms of the disease and to improve quality of life . -
pubmed
The genotypes of ESBL producing
strains largely remain unknown in India ; hence the present study was aimed to determine the occurrence of ESBLs in
Escherichia coli and
Klebsiella pneumoniae , their molecular types and associated risk factors in a tertiary care hospital . -
pubmed
We investigated the possible combined effects of
gallic acid and
resveratrol , which are major antioxidants present in
fruit , including
grapes , on
PC12 rat pheochromocytoma (
PC12 ) cell
death . -
pubmed
We present a case of an invasive
Brenner tumor of the ovary in a
woman greater than age 70 . -
pubmed
CASE : A 77 - year - old
woman presented with a rare , invasive Brenner
tumor of the ovary . -
pubmed
Although different in ecology and susceptibility to control , the African
malaria vectors
Anopheles gambiae sensu stricto and
An . - pubmed
This suggests that prior research groups have used misidentified
strains of
Cop . - pubmed
minuta or fungal
strains that were only distantly related to the
Cop . - pubmed
CONCLUSION : The
cyanoacrylate promoted a reliable
fallopian tube obstruction without
fibrosis in an
animal model exhibiting a similar tube diameter to that found in
women . -
pubmed
Production of acute
rheumatic - like heart lesions in
mice . -
pubmed
They were then evaluated together with the previously prepared
UDP - furanoses for their anti - parasitic properties against
Leishmania donovani promastigotes , one of the agents responsible for
visceral leishmaniasis . -
pubmed
In an effort to identify key regulators of the crosstalk between
melanoma cells and the
melanoma - skin microenvironment , primary and metastatic
human melanoma cells were seeded into skin organ cultures ( SOCs ) and grown for two weeks . -
pubmed
The differential protein abundances were calculated by spectral counting , the results of which provides evidence that cell - matrix and cell - adhesion molecules that are upregulated in the presence of these
melanoma cells recapitulate proteomic data obtained from comparative analysis of
human biopsies of invasive
melanoma and a tissue sample of adjacent , noninvolved skin . -
pubmed
A case is presented of a 43 - year - old
man without pre - existing medical comorbidities who sustained atraumatic bilateral
patellar tendon ruptures following a treatment course of
fluoroquinolone medication . -
pubmed
Additionally ,
infection is often asymptomatic and as such goes untreated , creating reservoirs of
T. - pubmed
vaginalis could reduce the
human costs (
pregnancy complications ,
infertility ) , medical costs ( repeated doctor visits , increased susceptibility to
human immunodeficiency virus ( HIV ) infection ) , and societal costs ( stigma of
STI , cycles of untreated
infection ) associated with
trichomoniasis . -
pubmed
, a novel rapidly growing species related to the
Mycobacterium terrae complex and associated with
goat lung lesions . -
pubmed
Early
seizure detection in
rats based on vagus nerve activity . -
pubmed
Using left nerve VENG ,
seizures were detected in all
PTZ - treated
rats 103 + - 51 s ( mean + - SD ) before they developed tonic
seizures . -
pubmed
Control
rats did not develop
seizures and our method did also not detected
seizures in these
rats . -
pubmed
Seizures can be early detecting based on left nerve VENG in anesthetized
rats . -
pubmed
Diaphragmatic hernia in the
bovine ; case report . -
pubmed
BACKGROUND : Treatment options for
patients with inoperable primary or recurrent / metastatic
abdominopelvic malignancies are limited , and these patients have short lifespan . -
pubmed
METHODS : Consecutive 50
patients were identified from an Institutional Review Board ( IRB)-approved database undergoing ablation for unresectable
abdominopelvic malignancies via conventional surgical methods in a single institution between 07/2003 and 09/2009 . -
pubmed
RESULTS : Sixteen
patients had primary
tumors , and 34 presented with a recurrent / metastatic
malignancy . -
pubmed
The primary
tumors were abdominopelvic
sarcomas ( eight
patients ) , large
desmoids ( two ) ,
colorectal cancer (
CRC ) ( two ) , and
gastric cancer ,
mucinous cystic pancreatic neoplasm ,
gastrointestinal stromal tumor (
GIST ) , and
carcinoid ( one each ) . -
pubmed
The recurrent / metastatic
tumors were
CRCs ( 16
patients ) , abdominopelvic
sarcomas ( 12 ) , and
GIST ,
prostate cancer ,
bladder cancer ,
melanoma ,
adrenal cancer , and
pseudomyxoma peritonei recurrences ( 1 each ) . -
pubmed
Patients with primary
tumors had 5 - year survival of 18 % compared with no survivors at 5 years in the recurrent / metastatic group ( P = 0.002 ) . -
pubmed
Patients with ablated primary
tumors have a survival advantage over
patients who have ablation for recurrent / metastatic disease . -
pubmed
In the first investigation of this question , twenty nonverbal
children with
autism with a developmental age of 24 and 36 months , and twenty matched typical children , were presented with an experimental box requiring that a hierarchical sequence of subgoals be performed before it could be opened . -
pubmed
The physiological parameters characterizing
human capacities ( the ability to move , reproduce or perform tasks ) evolve with ageing : performance is limited at birth , increases to a maximum and then decreases back to zero at the day of
death . -
pubmed
METHODS : The model of experimental
periodontitis of
rats was established and treated by Bushenguchiwan with different doses . -
pubmed
Humoral immune responses to rhesus lymphocryptovirus (
rhLCV ) lytic
infection proteins were evaluated in the
rhesus macaque animal model for
Epstein - Barr virus ( EBV ) infection . -
pubmed
The
rhesus macaque animal provides a unique perspective on humoral responses to
EBV infection in
humans and can be a valuable model for
EBV vaccine development . -
pubmed
Incremental value of global systolic dyssynchrony in determining the occurrence of functional
mitral regurgitation in
patients with
left ventricular systolic dysfunction . -
pubmed
METHODS AND RESULTS :
Patients ( n = 136 ) with
LV systolic dysfunction ( ejection fraction & lt;50 % ) and at least mild
MR were prospectively recruited . -
pubmed
OBJECTIVE : To understand the level of blood - lipid and prevalence of
dyslipidemia of
children aged 3 to 6 in Tianjin , so as to provide evidence for large - scale blood screening strategy and to develop intervention of
dyslipidemia and cardiovascular in children . -
pubmed
Screening and intervention programs on
dyslipidemia should be undertaken routinely in
children , in order to prevent adult
atherosclerosis and
coronary heart disease . -
pubmed
It is not clear whether centrally obese
individuals exhibit greater
cognitive impairment following acute stress . -
pubmed
Polyposis registry clinicians across Europe recruited
adolescents with
FAP to receive
aspirin ( 600 mg as 2 tablets / d ) and/or 30 g as 2 sachets / d in a 1:1 blend of
potato starch and high amylose
maize starch [ Hylon VII ] ) with placebo control for at least a year or until surgery before age 21 . -
pubmed
Benefit assessment of non - drug treatment strategies in
patients with essential
hypertension : reduction in salt intake : Executive summary of rapid report A05 - 21B , Version 1.0 The aim of this investigation was to assess the benefit of interventions for reducing salt intake compared to interventions that are not intended to reduce salt intake in
patients with essential
hypertension with reference to patient - relevant outcomes and criteria used in blood pressure control . -
pubmed
However , it has been reported that
humans feel an illusory thermal sensation in conjunction with an apparently - thermal visual stimulus placed on a prosthetic hand in the rubber hand
illusion ( RHI ) wherein an individual feels that a prosthetic ( rubber ) hand belongs to him / her . -
pubmed
[ Application of trans - abdominal - mediastinal drainage tube in
patients with high risk of esophagogastric or esophago - jejunal
anastomotic leakage ] . -
pubmed
METHODS : A total of 79
patients underwent thoraco - abdominal radical resection for
gastric cardia cancer , with high risk of leakage of the anatsomosis , from Aug. 2007 to Aug. 2011 were included in this study . -
pubmed
RESULTS : There was
anastomotic leakage in four
patients of the improvement group . -
pubmed
One among those five
patients had transdermal placement of thoracic drainage tube and was cured , and four among those five
patients had second debridement operation , with 3 cured and one
death case . -
pubmed
CONCLUSIONS : Although putting trans - abdominal - mediastinal drainage tube can not prevent the leakage of esophagogastric or esophago - jejunnal anastomosis , it can reduce the systemic inflammatory responses ,
death and painful suffering of the
patients caused by
anastomotic leakage . -
pubmed
An epidemiological survey on
dogs was conducted applying serological methods in two Italian regions where
angiostrongylosis is endemic in foxes . -
pubmed
We retrospectively reviewed the endosonographic features of four
patients with
gastric schwannomas and their computed tomography imaging results . -
pubmed
Disappearance of the radial
pulse on palpation indicated the
systolic arterial pressure , as Riva - Rocci confirmed by calibration experiments in animals and with
human cadavers . -
pubmed
Commensal
Escherichia coli residing in the
human gut produce
colibactin , a small - molecule genotoxin of unknown structure that has been implicated in the development of
colon cancer . -
pubmed
Analysis of 1543
patients with advanced
osteoarthritis of the hip . -
pubmed
PATIENTS AND METHODS : The femoral neck length of 1543
patients with
osteoarthritis grade 3 and 4 was measured on calibrated pelvic radiographs . -
pubmed
OBJECTIVE : This study aims to examine whether blood pressure reductions differ by
estrogen use among
overweight glucose - intolerant
women . -
pubmed
METHODS : We conducted a secondary analysis of
Diabetes Prevention Program postmenopausal
participants who used oral
estrogen with or without
progestogen at baseline and 1 - year follow - up ( n = 324 ) versus those who did not use oral
estrogen with or without
progestogen at either time point ( n = 382 ) . -
pubmed
CONCLUSIONS : Among
overweight women with
dysglycemia , the magnitude of blood pressure reductions after ILS is unrelated to postmenopausal
estrogen use . -
pubmed
BACKGROUND AND OBJECTIVES :
Women 's use of
alcohol in pregnancy is associated with an increased risk of
fetal loss and
birth defects . -
pubmed
Acute
gallbladder necrosis in a
patient with acute
type B aortic dissection . -
pubmed
We experienced the case of a 42 - year - old
woman who suffered from acute gallbladder
necrosis that occurred the following day after the onset of acute
type B aortic dissection . -
pubmed
METHODS : We prospectively investigated six stable
TBI patients who underwent cranioplasty more than 90 days after effective decompressive craniectomy . -
pubmed
METHODS :
Weight gain and parasympathetic nervous system activity were assessed in 30 preterm
infants randomly assigned to a massage therapy group or to an exercise group . -
pubmed
METHODS :
Colorectal cancer tissues from
patients with or without
liver metastases were profiled to identify differentially expressed microRNA . -
pubmed
Correlation between miR-181a expression , the most differentially expressed microRNA , between
patients with and without
liver metastasis , and its downstream target genes were investigated using qRT - PCR . -
pubmed
UNLABELLED : The dietary exposure of the
human population to the prions responsible for the
bovine spongiform encephalopathy (
BSE ) epizooty has led to the emergence of variant
Creutzfeldt - Jakob disease (
vCJD ) . -
pubmed
Compared to the " gold - standard " RIII model routinely used for endpoint titration of
vCJD / BSE prions , either method improved the sensitivity by & gt;2 orders of magnitude and allowed reevaluating the infectious titer of spleen from a
vCJD individual at disease end stage to & gt;1,000 - fold - higher values . -
pubmed
We conclude that hfMSCs could be used as a new source of cells to treat
patients with
osteogenic diseases , as well as to understand the mechanisms of immunosuppression by MSCs . -
pubmed
This study aimed to examine the alterations in coagulation parameters involved at different steps of hemostasis in
patients with
Crohn ' s disease and
ulcerative colitis , in comparison with healthy individuals . -
pubmed
Alteration of immunoproteome profile of
Echinococcus granulosus hydatid fluid with progression of
cystic echinococcosis . -
pubmed
BACKGROUND :
Cystic echinococcosis (
CE ) , caused by
Echinococcus granulosus metacestode , invokes a serious public health concern . -
pubmed
Immunoproteome analysis combined with imaging studies may be practical in the differential diagnosis of
CE from
AE and other
cystic lesions , as well as for staging CE , which are pertinent to establish appropriate
patient management . -
pubmed
Efficacy and safety of
reslizumab in
patients with moderate to severe
eosinophilic asthma . -
pubmed
BACKGROUND CONTEXT : New spinal interventions or implants have been tested on ex vivo or in vivo
porcine spines , as they are readily available and have been accepted as a comparable model to
human cadaver spines . -
pubmed
Clinical and epidemiological differences between
septic arthritis of the knee and hip caused by
oxacillin - sensitive and -resistant
s. - pubmed
OBJECTIVE : To establish the risk factors for
joint infection by
oxacillin - resistant
Staphylococcus aureus (
MRSA ) using clinical and epidemiological data . -
pubmed
This study investigated the effects of the
ethanol extracts of
mung bean testa ( MBT ) on the metabolic
inflammation - induced lipogenesis in gastrocnemius muscle of KK - Ay diabese
mice . -
pubmed
Ethanol extracts of
MBT were orally administered to diabese KK - Ay
mice for 4 weeks after diet - induced
obesity model was generated by feeding a 60 % high - fat diet for 3 weeks . -
pubmed
A 71 - year - old
man diagnosed with
lung cancer in the right lower lobe with invasion to the middle lobe underwent right lower and middle lobectomy with mediastinal lymph node dissection . -
pubmed
Chinese rhesus macaques ( CRMs ) are ideal experimental animals for studying the pathogenesis of
human immunodeficiency virus ( HIV ) and simian immunodeficiency virus (
SIV ) and for vaccine research . -
pubmed
SHIV89.6 has been reported to be an attenuated virus because , in most cases ,
SHIV89.6 infection only causes limited alteration of immune cells and tissues , and it has been used commonly for vaccine research . -
pubmed
In this study , we found that 6 of 14
SHIV89.6 - infected
CRMs died within 127 weeks after
infection . -
pubmed
BACKGROUND : Traditional approaches for nighttime glycemic control in
glycogen storage disease type I (
GSDI ) include continuous tube feeding , or ingestion of uncooked
corn starch ( CS ) at bedtime . -
pubmed
The aim of this study was to evaluate whether stable nighttime
glucose control can be achieved with other types of slowly digested
carbohydrates in adult
GSDI patients . -
pubmed
CONCLUSION : Consumption of cooked
pasta is a suitable and more palatable alternative to uncooked
corn starch to achieve nighttime
glucose control in adult
patients with
GSDI . -
pubmed
An advanced level of understanding of the complex physiological function and control of the
human body may be combined with skill in heat transfer analysis and design to develop life - saving and
injury - healing medical devices . -
pubmed
METHODS : A single center retrospective study of 96
patients with
mRCC from December 2004 to August 2013 . -
pubmed
Profiling of spatio - temporal characteristics of altered
pain sensitivity ( evoked
pain to mechanical and/or heat stimuli ) allows implications on the mechanisms likely active in a given
patient , including peripheral or central sensitization , intraspinal or descending inhibition . -
pubmed
Patterns of international normalized ratio values among new
warfarin patients with nonvalvular
atrial fibrillation . -
pubmed
Limited information exists regarding the relationship between international normalized ratio ( INR ) control / stability and the discontinuation of
warfarin therapy among
patients with
nonvalvular atrial fibrillation (
NVAF ) . -
pubmed
strains isolated from
human feces was examined in vitro against a wide range of Gram negative pathogenic
strains isolated from 30 infant
patients ( 3 days to 5 years old ) with
diarrhea . -
pubmed
strains , the largest spectrum of antimicrobial activity against 9 of the 18 enteropathogenic
strains was revealed for a
B. - pubmed
OBJECTIVES : To explore the relation between the baseline aortic valve gradient ( AVG ) as a continuous variable and clinical outcomes following transcatheter aortic valve implantation ( TAVI ) in general and specifically in
patients with high - gradient
aortic stenosis (
AS ) . -
pubmed
Rutin ameliorates kidney interstitial
fibrosis in
rats with
obstructive nephropathy . -
pubmed
BACKGROUND AIMS :
Critical limb ischemia (
CLI ) is a major health problem worldwide , affecting approximately 500 - 1000
people per million per annum . -
pubmed
METHODS : A cohort study of
patients undergoing surgery for
PTC was undertaken . -
pubmed
METHODS :
Patients who underwent surgical management of
ureterocele from 2003 to 2015 were identified ; those who received concomitant fluoroscopic RUC were selected for the case series . -
pubmed
RESULTS : Of the 43
patients that underwent surgery for suspected
ureterocele , 28 underwent cystoscopy + RUC ( 10 M : 18 F ) at a median age of 4.6 months and median follow - up of 37.0 months . -
pubmed
We found that a subset of
avian influenza viruses , including potentially pandemic
H5N1 , H7N9 , and
H9N2 viruses , could infect
human pulmonary endothelial cells (
HULEC ) with high efficiency compared to
human H1N1 or
H3N2 viruses . -
pubmed
Notably , certain
avian influenza viruses have evolved to escape this restriction , possibly contributing to virus - induced
pneumonia and severe
lung disease in
humans . -
pubmed
IMPORTANCE :
Avian influenza viruses , including
H5N1 and
H7N9 , have been associated with severe
respiratory disease and fatal outcomes in
humans . -
pubmed
Although
acute respiratory distress syndrome (
ARDS ) and progressive
pulmonary endothelial damage are known to be present during severe
human infections , the role of pulmonary endothelial cells in the pathogenesis of
avian influenza virus infections is largely unknown . -
pubmed
By comparing
human seasonal
influenza strains to
avian influenza viruses , we provide greater insight into the interaction of
influenza virus with
human pulmonary endothelial cells . -
pubmed
Overall , this study provides a mechanism by which
human endothelial cells limit replication of
human influenza virus strains , whereas
avian influenza viruses overcome these restriction factors in this cell type . -
pubmed
These
patients were divided as patients with isolated
carpal tunnel syndrome ( n = 337 ) or coincident
carpal and cubital tunnel syndromes ( n = 178 ) , then characterized according to demographics , medical history , physical examination , and NCS results . -
pubmed
The variables involved are routinely used to assess the cubital tunnel , and all component factors of the KB score were of equivalent clinical weight in assessing
patients with potential coincident
compression neuropathy . -
pubmed
CH treatment was initiated but the
patient maintained
recurrence rates compatible with chronic
CH , even after increasing
verapamil to 460 mg / day . -
pubmed
With this treatment the severity and
recurrence of
CH substantially decreased , despite the
patient 's autonomous decision to take
lithium only during the acute phase of the cluster . -
pubmed
OBJECTIVE : The aim of this study was to evaluate the efficacy of a nutritional program , which is characterized by a different modulation of proteins , in adult
patients with
sarcopenic obesity . -
pubmed
METHODS : We studied 18
obese women aged 41 - 74 years . -
pubmed
CONCLUSIONS : In our study ,
sarcopenic obese patients with high - protein diet showed an improvement in muscle strength . -
pubmed
Knowledge of physiological microhemodynamic values of bone and striated muscle in NSG
mice makes it possible to analyze pathophysiological processes at these anatomic sites , such as
tumor growth ,
tumor metastasis , and
tumor microcirculation , as well as the response to therapeutic agents . -
pubmed
Paraquat - Induced
Movement Disorder in Relation to Oxidative Stress - Mediated Neurodegeneration in the Brain of
Drosophila melanogaster . -
pubmed
PQ has been shown to induce
PD - like phenotype in experimental
animals . -
pubmed
Drosophila , a valuable laboratory model
organism , is widely used to study
neurodegenerative disorders including
PD . -
pubmed
The acute ( single dose ) PQ model of
PD in
Drosophila is associated with high mortality as well as reversibility of
locomotor deficits and , therefore , does not replicate the disease phenotype . -
pubmed
We have investigated the relevance of the acute and multiple ( sublethal ) dose of PQ to induce
PD - like symptoms in
Drosophila and shown that multiple - dose of PQ induces irreversible
locomotor impairment without significant mortality . -
pubmed
Our study has provided ultrastructural evidence for neurodegeneration involving
mitochondrial damage in the brain caused by free radical - induced oxidative stress , which leads to
locomotor impairment in
Drosophila . -
pubmed
The multiple ( sublethal ) dose of PQ could be an appropriate
Drosophila model to induce
PD - like symptoms of
movement disorder associated with neurodegeneration , which could be useful to evaluate neuroprotective compounds . -
pubmed
Psoriasis is a
T - cell - mediated skin disease with autoimmune nature that is generally not observed in
animals , this lack of a relevant experimental
animal model of
psoriasis has hindered the investigation of pathogenesis of disease . -
pubmed
In this study , we present an IMQ
animal model of
psoriasis and designed a safe fusion peptide carrier , spherical nucleic acid gold nanoparticles conjugate , to improve penetration of the siRNA into the cells and skin and their targeting ability to gene regulation . -
pubmed
Microscopic evaluation of
mice back skin and immunohistochemistry process approved Inhibitory effect of SNA - NCs siRNA in the
mouse model of
psoriasis . -
pubmed
Participants :
Patients with
PA ( n = 184 ) . -
pubmed
Meta - analysis of adjunctive
dexamethasone to improve clinical outcome of
bacterial meningitis in
children . -
pubmed
Documents of randomized controlled trials ( RCT ) related to the treatment of
bacterial meningitis in
children with
dexamethasone published since the establishment of the databases to December in 2016 were retrieved from the databases of Cochrane Library , Pubmed , MEDLINE , EMBASE , Chinese BioMedical Literature Database , and China National Knowledge Infrastructure . -
pubmed
The results of meta - analysis have shown that
patients who received
dexamethasone have significantly lower risks in incidence of
hearing loss ( OR = 0.68 , 95%CI 0.53 - 0.89 , P = 0.004 ) and severe
neurological sequelae ( OR = 0.59 , 95%CI 0.37 - 0.95 , P = 0.03 ) , but the follow - up mortality is hardly effected ( OR = 0.86 , 95%CI 0.67 - 1.10 , P = 0.23 ) . -
pubmed
CONCLUSIONS : Evidence has proven that the adjunctive administration of
dexamethasone is conducive to treating
children with
bacterial meningitis to a certain extent , to decreasing the possibility of
hearing loss and severe
neurological sequelae , but has no significant effect on the follow - up mortality . -
pubmed
Positive blood culture and
inflammation at the vascular access site were highest in
patients with nontunneled central lines ( 1.65 and 1.54/100 patient - months , respectively ) when compared to those with other types of vascular access . -
pubmed
HYPOTHESIS : Differences occur in the prediction of cardiac events using 2D STE in
AMI vs
CAD patients . -
pubmed
METHODS : In this prospective study , 94
patients with a first
AMI and successful revascularization , and 137
patients with stable
CAD after complete revascularization were included . -
pubmed
Strain parameters in
AMI and
CAD patients were significantly different with respect to the occurrence of a cardiac event . -
pubmed
CONCLUSIONS : Global strain parameters by 2D STE may be useful for the prediction of cardiac events in
patients with
CAD but add no supplemental information to baseline characteristic and ejection fraction in patients with
AMI . -
pubmed
We asked the
patients about their
pain and degree of satisfaction according to a visual analogue scale ( VAS ) , their memory of the procedure , mental status and the presence of uncomfortable symptoms on the day of the procedure and the day afterwards . -
pubmed
No significant differences were found in the number of
patients with
pain ( VAS & gt;=1 ) , adverse events and
discomfort between the two groups . -
pubmed
: : The occurrence of
MS at several unusual anatomic sites and its spectrum of morphologic patterns can result in significant diagnostic difficulty , and correct diagnosis is particularly important because of its high tendency to recur locally and to metastasize , which highlights the importance of diagnostic recognition , ancillary molecular genetic testing , and close clinical follow - up of
patients with
MS . -
pubmed
BACKGROUND :
Traumatic injury is well known to increase the risk of
venous thromboembolic events (
VTEs ) , occurring in up to 58 % of
trauma patients . -
pubmed
RESULTS : A total of 2519
trauma patients were included with 97 ( 3.8 % ) developing
VTE . -
pubmed
GNF generates many electromagnetic hotspots as surface - enhanced Raman spectroscopy ( SERS ) excitation sources , and enables large - area visualization of molecular vibration fingerprints of metabolites in
human cancer xenografts in livers of
immunodeficient mice with sufficient sensitivity and uniformity . -
pubmed
( 0.319 + - 0.028 h-1 for strain I09 and 0.397 + - 0.064 h-1 for
strain I13 ) and
Ps . - pubmed
Human clinical trials of & gt;= 10
patients with
peri - implant diseases , treated with surgical or non - surgical approaches and laser therapy , and a follow - up period of & gt;= 6 months , were included . -
pubmed
The prevalence and association of
patients with impaired left ventricular ejection fraction and complete
left bundle - branch block in Taiwan . -
pubmed
Baseline clinical characteristics , electrocardiography and ECG parameters , in
patients with
cLBBB were compared among those with three different LVEFs ( EF & lt;35 % , 35%<= EF<50 % , and EF & gt;=50 % ) . -
pubmed
Multivariable logistic regression analysis were conducted to identify independent predictors of impaired LVEF in
patient with
cLBBB . -
pubmed
RESULTS : The prevalence of
cLBBB was 0.4 % ( 648
patients ) , and it increased with age . -
pubmed
The effects of age on the distributions of
patients with
cLBBB by three different EF statuses were significantly disparate . -
pubmed
BACKGROUND : Until recently , the
Chagas disease vector ,
Triatoma infestans , was widespread in Arequipa , Peru , but as a result of a decades - long campaign in which over 70,000 houses were treated with insecticides , infestation prevalence is now greatly reduced . -
pubmed
Growth disturbance from a
physeal injury is considered by many surgeons to be the most feared iatrogenic surgical complication after anterior cruciate ligament ( ACL ) reconstruction in skeletally immature
patients , typically resulting in
valgus , recurvatum , and/or a short limb . -
pubmed
BACKGROUND : Dental
trauma injuries are frequent in
children and
adolescents and can result in a sequela of future complications . -
pubmed
Finally , acoustic angiography is employed to assess the consequences of
taxane release at the
tumor site in Nu / Nu -
tumor - bearing
mice . -
pubmed
The median onset time of
EBV reactivation was 49 days ( range , 14 - 561 ) , including five
patients who developed
post - transplant lymphoproliferative disorder ( EBV -
PTLD ) . -
pubmed
Twenty - one
patients ( 17 % ) developed RTX - related
neutropenia . -
pubmed
Purpose : To compare the efficacy , safety , and potential advantages of the preservative - free versus preserved
brimonidine % 0.15 preparations in
patients with
primer open - angle glaucoma (
POAG ) or
ocular hypertension (
OHT).Methods : Forty - two eyes of the 21 treatment - naive
patients with
POAG or OHT were enrolled in this study . -
pubmed
Ocular symptom values of the
patients were evaluated with a scale of 0 - 4 ( 0 = no discomfort and 4 = severe
discomfort).Results : Both of the
brimonidine tartrate formulations resulted in statistically similar IOP reduction ( preserved formulation ; -5.2 mmHg [ 22.9 % reduction ] preservative - free formulation ; -5.7 mmHg [ 24.1 % reduction ] , p = 0.37 ) . -
pubmed
A total of 60
patients ( 12.1 % ) died at 6 months [ 40 with
anemia ( 17.5 % ) and 20 without
anemia ( 7.5 % ) , P = 0.001 ] . -
pubmed
The association of
anemia and mortality was different according to
frailty status , being significant in patients without
frailty ( hazard ratio 3.94 , 95 % CI 1.84 - 8.45 , P = 0.001 ) , but not in frail
patients ( hazard ratio 1.17 , 95 % CI 0.53 - 2.57 , P = 0.705 ) , ( P value for interaction = 0.035 ) . -
pubmed
The association between
anemia and mortality was especially significant in robust patients , whereas the poorer prognosis in frail
patients was not modified by the presence of
anemia . -
pubmed
Underlying
cancer must be ruled out in
patients presenting with multiple subcutaneous nodules with suspicious history , physical , and radiological findings . -
pubmed
Among
patients with acquired
TTP , the association between delayed plasma exchange and risk of
death was evaluated using Cox regression . -
pubmed
Acquired
TTP was confirmed in 61
patients . -
pubmed
36 % of suspected
TTP and 13 % of confirmed
TTP patients died . -
pubmed
The results also showed that the nanoliposomes do not induce
cytotoxicity and cell
death in
human MSCs and no perturbation of proliferation for all the times and the tested concentrations , as well as the combined nanoliposomes and hydrolysates ( HTS ) at a concentration of 0.1 mg / mL. -
pubmed
Conclusion :
Melatonin seems safe and effective for use in
patients with SDs in early - stage
cirrhosis in the short term . -
pubmed
Nephrotoxicity of these compounds against
human renal tubular epithelial (
HK-2 ) cells were evaluated using the
MTT assay . -
pubmed
CONCLUSIONS : In the largest national study to date , we found that
thrombosis in NICU
patients is associated with
prematurity , low
birth weight ,
sepsis , and invasive procedures . -
pubmed
Shigella sonnei surface polysaccharides are well - established protective antigens against this major cause of
diarrhoeal disease . -
pubmed
Aqueous Extracts of
Morus alba Root Bark and
Cornus officinalis Fruit Protect against
Osteoarthritis Symptoms in
Testosterone - Deficient and
Osteoarthritis - Induced
Rats . -
pubmed
We determined that the 12 - week consumption of MBW and CFW could alleviate
testosterone - deficiency syndrome and
osteoarthritis (
OA ) symptoms in
testosterone - deficient
rats , and the action mechanisms were explored . -
pubmed
In conclusion , MBW , possibly CFW , could be effective alternative therapeutic agents for preventing
osteoarthritis in
testosterone - deficient elderly
men . -
pubmed
Respiratory and
Reproductive Impairment of Commercial Layer
Chickens After Experimental Infection with
Gallibacterium anatis Biovar haemolytica . -
pubmed
We used 500 base pairs of a 16S ribosomal RNA gene and the 16S-23S ribosomal RNA intergenic spacer , partial sequence in an experimental
infection trial in commercial White Shaver layer
chickens aged 19 wk . -
pubmed
Severe lesions in the form of
hemorrhagic pneumonia ,
catarrhal tracheitis , ovarian follicle and oviductal regression , and
septicemia were evident on necropsy , demonstrating the pathogenicity of
G. - pubmed
Methods : A cross - sectional study was conducted with 22
patients with
IIH and 11 controls . -
pubmed
Conclusion : The GCC was thinner in the
patients with
IIH compared to the controls , and there was an association between GCC and
optic disc pallor . -
pubmed
Letter : Treatment of
allergy to
cow 's milk . -
pubmed
One hundred seventy - eight
patients with
transient ischemic attacks (
TIAs ) or small
strokes with slight symptoms persisting for more than 24 hours ( incomplete recovery = IR ) ( TIA - IR ) from both the carotid and the vertebrobasilar systems were treated with anticoagulants . -
pubmed
Only one
patient had a lethal
cerebral infarction when the thrombotest values were above the therapeutic level ; no other
infarction happened during the treatment period . -
pubmed
During the observation period , six
patients had
cerebral infarctions . -
pubmed
All the
cerebral infarctions were in
patients who had their initial
TIA /
TIA - IR from the carotid territory ( within the same carotid artery which earlier had given symptoms ) . -
pubmed
The investigation shows that long - term anticoagulant treatment is useful , especially in
patients with carotid
TIA /
TIA -
IR , and that this treatment should continue as long as the
patients can manage it . -
pubmed
Symptomatic
osteonecrosis occurred in 8 out of 68
patients with
systemic lupus erythematosus . -
pubmed
Multiple joints were involved in 3
patients , and
weight - bearing joints were most frequently affected . -
pubmed
Osteonecrosis tended to occur early in the disease , and the
patients had all received
corticosteroids . -
pubmed
Although development of
gynecomastia in a
patient with
cancer may indicate persistence or regrowth of a
tumor , we studied three
patients with
lymphoma in whom development of
gynecomastia during or after chemotherapy did not portend a poor outcome . -
pubmed
The serum
estradiol level of one
patient was elevated at the onset of
gynecomastia , but it fell to normal as the
gynecomastia resolved spontaneously over a three - month period during which the
patient received no chemotherapy . -
pubmed
In a second
patient ,
gynecomastia resolved over a period of eight months while the
patient continued on maintenance chemotherapy , and he remains clinically well in remission 21/2 years after onset of
gynecomastia . -
pubmed
In the third
patient ,
gynecomastia developed while the
patient was in complete remission and off of all therapy , and it remained unchanged for the duration of a 21/2 - year remission without therapy . -
pubmed
To evaluate the extent and relative activity of the inflammatory process , we scanned
patients with
idiopathic pulmonary fibrosis using
gallium-67 , a radionuclide known to concentrate in regions of
inflammation . -
pubmed
Evaluation of
67Ga scans in 30
patients with
idiopathic pulmonary fibrosis and 19 control subjects demonstrated that the 67Ga - index in the group with
idiopathic pulmonary fibrosis was significantly higher ( P less than 0.001 ) than that in the control group . -
pubmed
When compared with lung biopsy morphologic studies in 22
patients with
idiopathic pulmonary fibrosis , the 67Ga - index correlated with the degree of interstitial cellularity ( P less than 0.05 ) and the degree of alveolar cellularity ( P less than 0.005 ) . -
pubmed
When compared with cellular analysis of bronchoalveolar lavage fluid in 17
patients with
idiopathic pulmonary fibrosis , the 67Ga - index correlated with the differential percentage of neutrophils ( P less than 0.05 ) , but not lymphocytes , eosinophils , or macrophages . -
pubmed
These studies indicate that
67Ga accumulates in the lungs of
patients with
idiopathic pulmonary fibrosis and is probably associated with the active inflammatory state . -
pubmed
All
dogs had frequent
ventricular premature beats (
VPB ) and five of six
dogs had
ventricular tachycardia during the first 4 days after the cryolesion ; only one of the six
dogs continued to have
VPBs after 1 week , and this
dog had identical VPBs before the creation of the cryolesion . -
pubmed
Neither control
dog had
VPBs . -
pubmed
VPBs in these
animals were shown to originate at the border of the cryolesion . -
pubmed
During an oral
glucose tolerance test the 2 h plasma
glucose value was significantly higher in
patients with
myotonic dystrophy compared to controls , and 5 out of the 7
patients demonstrated
hyperinsulinemia . -
pubmed
No effects such as changes in the
patient 's BP ,
pulse rate and rectal temperature were noted during the observation period , and no side - effects such as
pain ,
dyspnoea ,
nasal symptoms ,
exanthema or
thrombophlebitis , nor any other symptoms to suggest that the solution was not well tolerated . -
pubmed
Reversal of
renal failure and control of
hypertension in
patients with
occlusion of the renal artery . -
pubmed
Results of arteriographic investigation of
patients with deteriorating renal function or poorly controlled
hypertension have revealed that
thrombosis of the renal artery is not an uncommon exacerbating factor . -
pubmed
Seventeen
patients with one or more occluded renal arteries had an operation to improve renal function or to control
hypertension . -
pubmed
Stenosis of the contralateral renal artery was present in addition to the occlusion in four
patients . -
pubmed
Eight
patients with
renal failure had marked improvement in renal function after revascularization of the occluded renal arteries . -
pubmed
Preoperative control of
hypertension was difficult in 16 of the 17
patients . -
pubmed
The
hypertension was unchanged in two
patients . -
pubmed
Sepsis - related complications occurred in 51
patients ( 27.4 % ) , including 3 surgical
deaths , 30
wound infections , and 18 others . -
pubmed
For good coverage of
cholangitis prior to operation , the proper antibiotic should have potency against gram - positive Enterococcus , gram - negative bacilli , especially
Pseudomonas and
E. - pubmed
An analysis of results of rheological properties of blood in 45
patients with different forms of
postthrombotic disease of lower extremities has shown that 78 % of the patients have
erythrocytosis and all the patients have
hyperviscosity shifts . -
pubmed
Thirteen
patients with
faecal incontinence and 26 control subjects were studied to investigate whether a quantitative electromyographic ( EMG ) signal could be correlated to anal manometry . -
pubmed
Diphenoxylate -
atropine (
Lomotil )
overdose in
children : an update ( report of eight cases and review of the literature ) Eight pediatric accidental
overdoses of
diphenoxylate -
atropine (
Lomotil ) are reported , and 28 literature cases are reviewed . -
pubmed
Only 6 of 36
children showed signs of
atropine overdose (
central nervous system excitement ,
hypertension ,
fever , flushed
dry skin ) . -
pubmed
The authors treated eight
children with
corticoid dependent syndrome caused by minor
abnormalities of the glomeruli with
Cyclosporin A. They administered
Cyclosporin , 5 mg / kg/24 h. , for a period of 8 - 16 weeks . -
pubmed
After initial
infection with human immunodeficiency virus 1 (
HIV-1 ) , patients may remain asymptomatic for years before the onset of
acquired immune deficiency syndrome (
AIDS ) . -
pubmed
At present , it is not clear whether the
immune abnormalities in either the asymptomatic phase or in clinical
AIDS are due solely to direct effects of
HIV-1 or whether they also reflect host immunoregulatory mechanisms . -
pubmed
In this article , by Charles Via , Herbert Morse and Gene Shearer , the
immune abnormalities associated with early
HIV-1 infection are compared with immune abnormalities found in three
murine models of
autoimmunity and
immunodeficiency , and it is suggested that host mechanisms contribute to defective helper T ( TH)-cell function early in the course of
HIV-1 infection . -
pubmed
Etiological factors for
gastric cancer , among others , involve consumption of smoked , salted , and pickled
fish of certain types . -
pubmed
In
rats , these
amines induce
cancer specifically in organs such as breast , colon , or pancreas , associated with Western - type nutrition where promotional elements such as dietary fat play an enhancing role . -
pubmed
The
patients who had an uncemented prosthesis had a significantly greater mean
blood loss , both intraoperatively ( p less than or equal to 0.05 ) and during each subsequent eight - hour interval on the first postoperative day ( p less than or equal to 0.05 ) . -
pubmed
When
patients who had
rheumatoid arthritis and
osteoarthrosis were considered separately , the results were similar ; that is , there was a significantly greater total postoperative
blood loss in each of the two groups when cement was not used ( p less than or equal to 0.025 ) . -
pubmed
In addition ,
sodium excretion was measured in
rats receiving lethal intestinal radiation
injury . -
pubmed
No recovery of these fluid compartments was observed in
rats destined to die from
intestinal radiation injury . -
pubmed
Since the demonstration of a humoral antiplatelet factor which causes a transient
ITP when given to healthy
volunteers ,
ITP has been thought of as an
autoimmune disease . -
pubmed
In our multicenter studies for severe
ITP ( less than 30 X 10(9)/liter platelet count ) in
children , we observed the existence of at least two subgroups of
ITP , namely rapid responders ( greater than or equal to 30 X 10(9)/liter platelet at 72 hours after the start of IVIG ) and slow responders ( less than 30 X 10(9)/liter platelet counts at 72 hours ) . -
pubmed
Slow responding
children were therefore comparable with adults with
ITP . -
pubmed
Because the adult type of
ITP occurs often in young
women , fetal risk must frequently be addressed . -
pubmed
To ascertain our experience with traumatic
perforations of the diaphragm , we reviewed the charts of 72
patients treated over a ten - year period . -
pubmed
Replication of
lymphocytic choriomeningitis virus in and clearance from the foot of the
mouse . -
pubmed
The hind foot was chosen for study of the mechanism by which adult
mice clear
lymphocytic choriomeningitis (
LCM ) virus . -
pubmed
A dose of 10(5 )
mouse infectious units ( IU ) was optimal , and in all
mouse strains tested
foot swelling commenced 6 days after injection , with maximal response on days 7 and 8 . -
pubmed
The rates of replication of the virus and its clearance were similar in the feet of
mice of four
strains tested , varying with regard to LCM virus - specific cell - mediated immunity . -
pubmed
In CBA / J
mice , virus elimination from the foot was followed for a longer time period and was incomplete up to 100 days after
infection . -
pubmed
Nineteen of these
patients had presented with
gastrointestinal hemorrhage at different postoperative intervals ( 4 days-23 years ) . -
pubmed
We did Cybex testing of thirteen
patients who had had a
rupture of the distal tendon of the biceps brachii . -
pubmed
In the presence of
metastases no undetectable serum Tg result was found in
patients off therapy , while four ( 6.9 % ) out of 58 samples from
patients with
bone and / or lung metastases and seven ( 31.8 % ) out of 22 samples from
patients with lymph node
metastases alone were undetectable ( falsely negative ) during suppressive therapy . -
pubmed
Herpesvirus infection in burned
patients . -
pubmed
[ Chemically induced
abnormalities of the masticatory skull in experimental
animals . -
pubmed
A 30 - year - old
patient was operated on as an emergency because of a left
atrial tumor . -
pubmed
Leg contracture in
mice : an assay of normal tissue response . -
pubmed
Leg
contracture , defined as the difference in extensibility of the control and irradiated hind legs of
mice , was found to correlate with single doses of radiation from about 20 to 80 Gy . -
pubmed
To determine the contribution of skin contraction to the overall leg
contracture response ,
mice were sacrificed and the
leg contracture measured before and after the removal of the skin of the leg . -
pubmed
For that reason , a comparison was made of the immunogenicities of
tumors induced with two doses of carcinogen in immunologically normal
mice and in
mice immunodepressed by adult thymectomy and irradiation . -
pubmed
Although there was some increase in the immunogenicity of
tumors induced in the immunosuppressed
mice , the same relationship between carcinogen dose and immunogenicity was observed in both groups of
mice . -
pubmed
Mechanism of
aspirin injury to
human gastroduodenal mucosa . -
pubmed
Gallium-67 scanning i
patients with
Crohn ' s disease : an aid to the diagnosis of
abdominal abscess . -
pubmed
In immune complex ( IC ) and autologous IC
nephritis in
rats , CCAq clearly inhibited the excretion of protein into urine and the elevation of blood
urea nitrogen (
BUN ) . -
pubmed
In the experiment employing NZB / NZW F1
mice , the
proteinurea , the elevation of
BUN level , and the production of antibodies were clearly inhibited by the administration of CCAq . -
pubmed
Legg - Calve - Perthes disease in
dogs : a comparison to
human Legg - Culve - Perthes disease . -
pubmed
The femoral heads of 12
dogs with naturally occurring
Legg - Calve - Perthes disease were studied by light and electron microscopic techniques . -
pubmed
One ( 7.1 % ) was an
infection with both
A. - pubmed
Heparin may be a superior alternative to
warfarin for the prevention of
thromboembolic disease in pregnant
women with cardiac valve prostheses . -
pubmed
Conversely ,
children having disruptive behavior with
attention deficit hyperactivity disorder or disruptive behavior with
oppoistional defiant disorder had 50 % lower suicide index than those with
adjustment disorders with concomitant
depression and higher adjusted TC levels ( 4.45 and 5.12 mmol / L , p = 0.0003). -
pubmed
This is the first reported survival of a pediatric
patient with
thermal injury and
ARDS by using ECMO for the treatment of
respiratory failure . -
pubmed
The independent impact of regional and total body composition and sex and thyroid hormone levels on resting energy expenditure ( REE ) was assessed in 121 healthy ,
overweight (
body mass index [
BMI ] , 25 to 42 kg / m2 ) , postmenopausal
women ( aged 49 to 58 years ) . -
pubmed
METHODS : Bronchial biopsy specimens were obtained from 27 clinically healthy
subjects with no history of
lung disease . -
pubmed
RESULTS : Nine of the 27
subjects showed
bronchial hyperresponsiveness as defined by a PC20FEV1 of & lt ; or = 8 mg / ml
histamine . -
pubmed
Segregated
subjects with and without
bronchial hyperresponsiveness showed no difference in spirometric results . -
pubmed
Thus , major components of a physiological pattern that predisposes laboratory
animals to
sodium - sensitive experimental
hypertension have now been observed to covary in ambulatory
humans . -
pubmed
Corticosteroid alteration of
carboplatin - induced
hematopoietic toxicity in a
murine model . -
pubmed
CA given subcutaneously at 0.5 mg / d per
mouse for 7 days before CB reduced CB - induced mortality due to
neutropenia from 88 % in controls to 14 % in CA - treated
mice ( P & lt ; .05 ) . -
pubmed
These findings suggest that treatment of
mice with CA induces cellular resistance of hematopoietic precursors to
platinum and , thus , reduces CB
hematotoxicity . -
pubmed
We present 16
patients with chronic
osteomyelitis treated with radical debridement and immediate free muscle transfer using the latissimus dorsi muscle preferably . -
pubmed
Patients with primary diseases that recur in the LTx (
hepatitis B and
CA ) do less well following LTx , with 5 - year survival rates of 55 and 40 % , respectively ) . -
pubmed
The initial migration and micromotion of the revision femoral stem stabilized with morselized impacted cancellous allograft and bone - cement and the influence of cement pressurization on fixation of the cement / allograft composite to the host were examined with
human cadaver femurs . -
pubmed
The effect of
coenzyme Q10 on
infarct size in a
rabbit model of
ischemia / reperfusion . -
pubmed
We assessed whether
coenzyme Q10 , administered intravenously either during or 1 h before
ischemia , can limit
infarct size in the
rabbit . -
pubmed
METHODS : Anesthetized open - chest
rabbits were subjected to 30 min of
coronary artery occlusion and 4 h of reperfusion . -
pubmed
In Protocol 1 , 12 min after beginning of
ischemia rabbits were randomized to intravenous infusion of 30 mg
coenzyme Q10 ( Eisai Co. , Japan ) ( n = 10 ) or vehicle ( n = 10 ) . -
pubmed
In Protocol 2 ,
rabbits were randomized to 30 mg
coenzyme Q10 ( n = 6 ) or vehicle ( n = 6 ) treatment 60 min before
ischemia . -
pubmed
CONCLUSIONS :
Coenzyme Q10 , administered acutely either during or 60 min before
myocardial ischemia , does not attenuate
infarct size in the
rabbit . -
pubmed
The
hypocalcaemia - inducing potential of urological irrigating fluids was studied in 7 young
men and in 10 prostatectomy
patients . -
pubmed
These results suggest that dilutional
hypocalcaemia can be expected to coexist with
hyponatraemia in
patients who develop the
transurethral resection syndrome . -
pubmed
Successful reversal of
diabetes by single donor isologous islet transplantation in a
mouse model . -
pubmed
In this paper , we describe the in vivo and in vitro findings on a
patient with clinical features of a mild
LAD-1 disorder , i.e. -
pubmed
Noncardiogenic pulmonary edema in a
patient with
diabetic ketoacidosis . -
pubmed
[ A 57 - year - old
man complaining of
dyspnea ] . -
pubmed
In fact , new findings reveal depressor , vasodilator , and antihypertensive actions that may be more apparent in
hypertensive animals or
humans . -
pubmed
Increased nonenzymatically glycosylated proteins in the vitreous humor of
diabetic animals . -
pubmed
We sought to determine whether glycation is increased in the vitreous humor of short - term
diabetic cats ( 6 months ' duration ) and
rabbits ( 2 months ' duration ) , using a
nitroblue tetrazolium colorimetric assay for
fructosamine . -
pubmed
Vitreous protein
fructosamine concentration was significantly higher in
diabetic cats and
rabbits , compared with that in control ( nondiabetic )
animals . -
pubmed
These results indicate that glycation is increased in the vitreous humor of short - term
diabetic animals , and therefore may be one of the initial triggers for clinically apparent
diabetic retinopathy . -
pubmed
Sixty
subjects aged 21 - 65 years with a diagnosis of nonpsychotic
anxiety or
insomnia were included . -
pubmed
Febrile convulsions ,
rat brains , and scientific pessimism . -
pubmed
The effects of intraamniotic
human neonatal urine and meconium on the intestines of the chick embryo with
gastroschisis . -
pubmed
An experimental study was performed to investigate the effects of intraamniotic
human neonatal urine and diluted meconium on the intestines of chick embryo with
gastroschisis . -
pubmed
Histopathologic changes of intestines induced by intraamniotic diluted meconium are consistent with the ones described for
human gastroschisis specimens . -
pubmed
The mechanisms of
chronic disease and recovery from
relapses in experimental
autoimmune encephalomyelitis (
EAE ) , an
animal model of
multiple sclerosis , are unknown . -
pubmed
Methyl methacrylate toxicity in
rat nasal epithelium : investigation of the time course of lesion development and recovery from short term vapour inhalation . -
pubmed
An investigation of the time course of development and recovery of the
nasal lesion induced in
rats by inhalation of
methyl methacrylate (
MMA ) was conducted . -
pubmed
UNLABELLED : The effects of
hypothyroid status on renal function have been poorly studied in
children . -
pubmed
We assessed the renal function of
hypothyroid infants detected during neonatal mass screening for
congenital hypothyroidism (
CH ) . -
pubmed
Eighty
hypothyroid infants and 20 age - matched normal
infants for controls were enrolled . -
pubmed
CONCLUSION : From these results we conclude that serum
creatinine levels are elevated in congenitally
hypothyroid infants . -
pubmed
The possibility of
impaired renal functions should be kept in mind when treating
hypothyroid infants . -
pubmed
OBJECTIVE : The purpose of this study was to describe the sonographic appearance of the common extensor origin in
cadavers and asymptomatic
volunteers , and to relate this appearance to the findings in
patients with
lateral epicondylitis . -
pubmed
SUBJECTS AND METHODS : Seventy - two elbows in 71
patients with
lateral epicondylitis were examined on sonography . -
pubmed
Most of the
patients ( 60/71 ) gave a history of repetitive
microtrauma . -
pubmed
CONCLUSION : Sonography of the common extensor origin can be used to confirm
lateral epicondylitis in
patients with
lateral elbow pain and provide information about the severity of the disease . -
pubmed
This shows the diverse origin of
HIV-1 strains circulating in the United Kingdom and may have implications for antiretroviral drug resistance . -
pubmed
Medical records of 99
patients with
isolated EA , 101 with isolated
anorectal malformations (
ARM ) and 15 with both
EA and
ARM , consecutively admitted to our unit , were reviewed . -
pubmed
For C592 G , this phenotype was confirmed by transfer to different
CMV strains and by restoration of full drug susceptibility after removal of the mutation . -
pubmed
This report retrospectively reviews the presentation , management and outcome in 14
patients with
intestinal malrotation . -
pubmed
Children presenting with recurrent or persistent
abdominal pain ,
vomiting or failure to thrive may well have
malrotation and should be investigated promptly and the condition corrected to avoid
midgut volvulus which is attended by significant morbidity and mortality . -
pubmed
The anocutaneous reflex and urinary continence in
children with
myelomeningocele . -
pubmed
OBJECTIVE : To examine the hypothesis that because most
patients with
myelomeningocele and a positive anocutaneous reflex have a competent sphincteric mechanism they are more likely to be continent on intermittent catheterization than those with a negative reflex , and to become so with less need for adjunctive surgical treatment . -
pubmed
PATIENTS AND METHODS : The study included 111
patients with
myelomeningocele treated for
urinary incontinence ; their present means of treatment and the outcome achieved were assessed and related to the presence or absence of an anocutaneous reflex . -
pubmed
The effect of
vanadium in lowering blood
glucose in
diabetic animals is well established ; however , the exact mechanism of action of
vanadium still eludes us . -
pubmed
In the present study we found that the plasma
glucose in
streptozotocin (
STZ )
diabetic animals was restored to normal following treatment with a single dose of
BMOV , an organic
vanadium compound , given by oral gavage ( 0.6 mmol / kg ) , similar to the response with chronic
BMOV treatment . -
pubmed
The main objective of this study was to evaluate the effect of 4 ( 5 , 20 , 80 , and 120 microg / kg ) doses of rFVIIa on correction of PT and the time to achieve hemostasis in cirrhotic
patients with
coagulopathy who are undergoing laparoscopic liver biopsy . -
pubmed
METHODS : Seventy - one
patients ( parts I and II ) with advanced
liver disease ( Child - Turcotte B or C ) , platelet count & gt ; or = 60,000 / mm3 , and PT in the range of 3 - 15 seconds above normal were included in the study . -
pubmed
None of the
patients required operative intervention or transfusion of blood / blood products to control
bleeding . -
pubmed
CONCLUSIONS : The results of this study suggest that treatment with rFVIIa may offer benefit for
patients with
liver disease undergoing laparoscopic biopsy . -
pubmed
[ Prophylactic and therapeutic effect of
oxymatrine on
D - galactosamine - induced
rat liver fibrosis ] . -
pubmed
CONCLUSIONS :
Oxymatrine shows prophylactic and therapeutic effect in
D - galactosamine induced
rat liver fibrosis . -
pubmed
Acute effects of higher than customary doses of
salmeterol and
salbutamol in
patients with acute exacerbation of
COPD . -
pubmed
In this study , we compared the acute effects of higher than customary doses of
salmeterol and
salbutamol in 20
patients with acute exacerbation of
COPD . -
pubmed
OBJECT : Radiosurgery is commonly used for the treatment of
patients with
glioma . -
pubmed
The goal of this study was to evaluate the safety and efficacy of radiosurgery in the management of
patients with
oligodendrogliomas (
ODGs ) or
mixed oligoastrocytomas (
OGAs ) . -
pubmed
METHODS : A retrospective chart review of
patients treated between May 1990 and January 2000 identified 18
patients ( 21
tumors ) with either an ODG ( 10 ) or a mixed
OGA ( 11 ) who had undergone radiosurgery . -
pubmed
Sixteen
patients had undergone one or more
tumor resections before radiosurgery ; in two
patients biopsy sampling alone had been performed . -
pubmed
Tumor grades at the most recent operation were Grade I ( one ) , Grade 2 ( one ) , Grade 3 ( 12 ) , and Grade 4 ( seven
patients ) . -
pubmed
CONCLUSIONS : For
patients with oligoastroglial
tumors that have failed to respond to conventional therapies , radiosurgery may provide some survival benefit . -
pubmed
This experiment showed that
Asthma - relieving decoction ( Dingchuan tang ) can protect experimental
asthma that blending of
histamine and
acetylcholine caused ( P & lt ; 0.05 [ symbol : see text ] P & lt ; 0.01 ) , can resist external trachea smooth muscle 's contracting that
histamine caused ( P & lt ; 0.01 ) , and can promote secretion of
phenol red of
rat 's respiratory tract ( P & lt ; 0.01 ) . -
pubmed
The objective of this longitudinal prospective cohort study was to determine whether level of prenatal
cocaine exposure , or the interaction between level of prenatal
cocaine exposure and contextual risk variables , was associated with a higher rate of infant - caregiver insecure attachment and
disorganized attachment , or with alterations in infant crying or avoidant behavior , after controlling for prenatal exposure to
alcohol ,
tobacco , and marijuana , the quality of the proximal caregiving environment , and other covariates . -
pubmed
OBJECTIVES : To document the causes of
upper airway obstruction in a population of
children with
Down syndrome and to highlight the role of associated comorbidities . -
pubmed
DESIGN AND SETTING : Review of 23 cases involving
children with
Down syndrome who were referred for
upper airway obstruction over a 2(1/2)-year period to the Pediatric Otolaryngology Service of the University of New Mexico , Albuquerque . -
pubmed
None of the
children had
subglottic stenosis . -
pubmed
Laryngomalacia was the primary diagnosis in 10
children ( 43 % ) , 8 of whom were younger than 1 month . -
pubmed
Obstructive sleep apnea was the primary diagnosis in 11
children ( 48 % ) , 8 of whom were older than 2 years . -
pubmed
All
children with
obstructive sleep apnea and 4
children with
laryngomalacia had a
secondary ear , nose , and throat disorder . -
pubmed
Gastroesophageal reflux was a comorbidity in 14
children ( 61 % ) . -
pubmed
CONCLUSIONS : The causes , severity , and presentation of
upper airway obstruction in
children with
Down syndrome are related to the age of the
child and to associated comorbidities . -
pubmed
Pathological physiology in
human cancer . -
pubmed
Correlations between behavior and urinary excretion of
indole amines and
catecholamines in
schizophrenic patients as affected by drugs . -
pubmed
The indications for imaging were : suspected compressive lesion of the anterior visual pathway in 57
patients ( 55.3 % ) , acquired
ocular motility disturbance in 20 patients ( 19.4 % ) , suspected orbital pathology in 11 patients ( 10.6 % ) ,
cerebrovascular accident in nine patients ( 8.7 % ) , and six
patients ( 5.8 % ) were imaged for either
headache or
sinusitis . -
pubmed
Effects of maternally administered
dexamethasone and acute
hypoxemia at 0.7 gestation on blood pressure and placental perfusion in
sheep . -
pubmed
Glucocorticoid administration to
women in
premature labor significantly decreases preterm infant morbidity and mortality . -
pubmed
Initial patient presentation may be a diagnostic dilemma to the family physician unfamiliar with testing methods for and the treatment and care of
patients with
MG . -
pubmed
The author focuses on the clinical features , electrodiagnostic testing , and treatment of
patients with
MG . -
pubmed
PD patients who were on stable and optimized dose of
levodopa were included in this study . -
pubmed
Maximum permissive dosage of
lactose and
lactitol for
transitory diarrhea , and utilizable capacity for
lactose in
Japanese female adults . -
pubmed
The maximum permissive dosage of
lactose not to induce transitory
diarrhea was 0.72 g / kg of
body weight and that of
lactitol was 0.36 g / kg of
body weight in
Japanese adults . -
pubmed
Our goal is to create mutant lines that model
human diseases and disease
syndromes and to make the mutant
mice available to the scientific research community . -
pubmed
Within the eye domain ,
mice are screened for
anterior and posterior segment abnormalities using slit - lamp biomicroscopy , indirect ophthalmoscopy , fundus photography , eye weight , histology , and immunohistochemistry . -
pubmed
The aim of this study was to investigate scintigraphic , immunohistological and ultrastructural changes associated with radiation - induced
dysfunction of the lachrymal gland in an established experimental
animal model . -
pubmed
MATERIALS AND METHODS : Eighty
patients who were diagnosed with small bowel
adenocarcinoma and treated at our institute between 1983 and 2003 were retrospectively reviewed . -
pubmed
Only 51.3 % of
patients were accurately proved preoperatively to have a
malignancy by endoscopic biopsy . -
pubmed
Lymph node
metastasis was the only independent factor predicting poor
disease - free survival in
patients undergoing curative resection . -
pubmed
In this study , we addressed this issue using the cell culture system of
rat schwannoma cell line
RT4 . -
pubmed
For the clinical study , the width of the anterior portion of the bursa was measured in both positions in both shoulders of 27
patients referred because of
shoulder pain and in eight asymptomatic
volunteers . -
pubmed
The objective was to evaluate the feasibility and efficacy of a short - term , multi - agent and dose intensive regimen in
AIDS patients with
Burkitt or Burkitt - like lymphoma (
BL /
BLL ) and to compare its efficacy with that of a conventional regimen . -
pubmed
This was a retrospective , multi - center cohort study of all
HIV-1 - infected patients diagnosed with
BL /
BLL between 1990 - 2004 . -
pubmed
In conclusion , the short and intensive GMALL protocol for
B - ALL /
NHL is feasible in
patients with
AIDS - BL /
BLL . -
pubmed
Insulin resistance , inflammatory biomarkers , and adipokines in
patients with
chronic kidney disease : effects of
angiotensin II blockade . -
pubmed
Patients with
chronic kidney disease (
CKD ) present a high prevalence of
insulin resistance (
IR ) . -
pubmed
These data demonstrate that
patients with
CKD have a high prevalence of
IR ,
metabolic syndrome , and
chronic inflammation and that the administration of the ARB
olmesartan improves IR and
inflammation markers in these
patients . -
pubmed
Plasma adipokine levels that are related to several metabolic risk factors in
patients with
CKD were not modified by ARB therapy . -
pubmed
These products were quantified in the plasma of
patients with
chronic renal failure before hemodialysis ( n = 6 ) ,
patients with chronic
heart failure ( n = 6 ) and controls ( n = 6 ) . -
pubmed
Do
workers exposed to intermittent aircraft noise suffer from occupational
deafness ? -
pubmed
The subsequent reports demonstrate the utility of molecular cytogenetics and expression analyses to the clinical management of
patients diagnosed with
hematological malignancies . -
pubmed
The objective of this study was to combine environmental and socio - economic factors to explain the spatial distribution of two emerging
human diseases in Belgium ,
Puumala virus (
PUUV ) and
Lyme borreliosis . -
pubmed
RESULTS : Negative binomial regressions including a correction for spatial endogeneity show that the spatial distribution of
PUUV and
Lyme borreliosis infections are associated with a combination of factors linked to the vector and host populations , to human behaviours , and to landscape attributes . -
pubmed
The spatial dependence resulting from a combination of endogenous and exogenous processes could be accounted for in the model on
PUUV but not for
Lyme borreliosis . -
pubmed
The objective of this study was to investigate the effects of RYGBP and BPD - RYGBP , a variant of BPD with a lower rate of
metabolic deficiencies than BPD , on
DM2 and the major components of
metabolic syndrome in
patients with morbid
obesity and
DM2 . -
pubmed
METHODS : The prospective database of our unit , from June 1994 until May 2006 , was analyzed and 137
patients with
DM2 were found . -
pubmed
CONCLUSIONS : RYGBP and BPD - RYGBP are safe and lead to normalization of blood
glucose , lipids ,
uric acid , liver enzymes and arterial pressure in the majority of
patients , although this variant of
BPD was more effective than RYGBP . -
pubmed
We suggest that further studies should also investigate its usefulness in
patients with milder degrees of
obesity ,
DM2 and
metabolic syndrome . -
pubmed
MATERIALS AND METHODS : Eighty - three consecutive
patients with
right ventricular outflow tract dysfunction ( 5 - 41 years , 76 %
tetralogy of Fallot ) referred to our center for cardiovascular magnetic resonance were studied . -
pubmed
Susceptibility to
impulse noise trauma in different species :
guinea pig ,
rat and
mouse . -
pubmed
OBJECTIVE : To test the hypothesis that there is different susceptibility to
impulse noise trauma in three species : the
guinea pig ,
rat and
mouse . -
pubmed
Melioidosis is caused by the facultative intracellular bacterium ,
Burkholderia pseudomallei . -
pubmed
This study has demonstrated that in vivo depletion of macrophages renders
C57BL / 6 mice highly susceptible to intranasal
infection with
B. - pubmed
Compared with control
mice , increased bacterial loads were demonstrated in spleen and liver of knockout
mice at day 2 postinfection , correlating with increased inflammatory infiltrates comprised predominantly of neutrophils and widespread
necrosis . -
pubmed
Following
infection with
B. - pubmed
If so , then those with
schizophrenia may have older fathers , since advancing paternal age is the major source of new mutations in
humans . -
pubmed
In order to tailor the best treatment in both newly diagnosed
MS patients and those already receiving treatment , the neurologist must carefully consider the risk of treating non - responders . -
pubmed
Palliating
delirium in
patients with
cancer . -
pubmed
Zoledronic acid reduces recurrent clinical
fracture in
patients with
hip fracture . -
pubmed
Preclinical studies in
animal models have given encouraging results , and synthetic peptide - based intervention in
human autoimmune rheumatic diseases is now approaching translational work into clinical settings . -
pubmed
Still another lineage contained the two subgenera Parasorghum and Stiposorghum with 2n=10 species and their
polyploid relatives with relatively large chromosomes ; ( 2 ) geographical divergence clearly existed in the
S. - pubmed
Children with
autism exhibit impairment in the processing of socioemotional information . -
pubmed
We collected structural and functional magnetic resonance images ( MRI ) in
children 8 to 12 years of age with high - functioning
autism ( n=12 ) and typical development ( n=15 ) . -
pubmed
The results showed that
children with
autism exhibited intact emotion matching , while showing diminished activation of the fusiform gyrus ( FG ) and the amygdala . -
pubmed
It has been shown that a lytic fluid for
dysentery bacilli can be obtained from the peritoneum of the
guinea pig by intraperitoneal inoculation of live
dysentery bacilli , and that the lytic action of such a fluid is not strictly specific , but that it exerts a group action on the
dysentery - colon -
typhoid group of bacilli . -
pubmed
It is conceivable that the resistant
strains are responsible for the untoward outcome of disease in
human beings . -
pubmed
Stem cells in the adult
rat spinal cord : plasticity after
injury and treadmill training exercise . -
pubmed
Most are found incidentally and
rupture in the nonpregnant
patient has an approximate 25 to 36 % mortality rate . -
pubmed
METHODS : We present the case of a 43 - year - old
man with a recent episode of
bacterial endocarditis with an incidental finding of a large 6 - cm
splenic artery aneurysm . -
pubmed
Two
dithiolethiones have been evaluated in
humans for
cancer prevention . -
pubmed
Here we have determined in the DIO
mouse model the efficacy of a related small molecule compound ,
Genz-112638 , which is currently being evaluated clinically for the treatment of
Gaucher disease , a
lysosomal storage disorder . -
pubmed
Whole body adiposity was not affected in normal
mice , but decreased in drug - treated
obese mice . -
pubmed
RESULTS :
Nerve swelling , considered significant when an increase in cross - sectional area was & gt ; or = 75 % , was observed in 43
patients . -
pubmed
Nerve swelling associated with a circumferential LA spread image , present in 37
patients , was associated with a sensory success rate of 86 % . -
pubmed
SUMMARY : It is apparent that subarachnoid clots play an important role in the development of delayed
vasospasm that is one of the major causes of mortality and morbidity in
patients with acutely ruptured
cerebral aneurysm . -
pubmed
SUMMARYStaphylococcus aureus is a leading cause of
infections in deployed service members . -
pubmed
Anxiety / stress among mothers living with
HIV : effects on parenting skills and child outcomes . -
pubmed
PATIENTS AND METHODS : For immunohistochemical studies , tissues from 46
patients with
LSCC at the Dr. Lutfi Kirdar Kartal Education and Research Hospital were used . -
pubmed
The main reason for ICU admission was
septic shock in 22
patients ( 55 % ) . -
pubmed
With the double objective of searching for a physiological brain circuit concerned with time estimation and establishing whether this circuit is dysfunctional in
schizophrenia patients , we carried out an activation likelihood estimate ( ALE ) meta - analysis of published functional neuroimaging studies . -
pubmed
In
schizophrenia patients , the analysis indicates significantly lower activation of most right hemisphere regions of the circuit , suggesting that it may be subject to a pattern of disconnectivity . -
pubmed
ADHD and
epilepsy common are both common childhood disorders and both can have significant negative consequences on a
child 's behavioural , learning , and social development . -
pubmed
Children with
epilepsy are at significant risk for
ADHD and there is a need for more studies focussing on safe and efficacious interventions for symptoms of
ADHD in this population . -
pubmed
Studies using
rodent models indicate that oscillatory phase - locking is disturbed in
schizophrenia , emphasizing the need for more studies of oscillatory synchrony in the hippocampal - prefrontal network . -
pubmed
Water samples were spiked at levels of 10(1 ) , 10(2 ) , 10(3 ) , and 10(4 ) CFU/100 ml with three -
strain cocktails of either
E. - pubmed
Six months after the surgery the
patient is symptom - free and without signs of
recurrence . -
pubmed
However , it must be considered in the differential diagnosis , especially in middle - aged male
patients without evidence of
atherosclerotic disease in whom
intermittent claudication has developed suddenly with a rapid progression or with fluctuation in severity . -
pubmed
METHODS : All fecal samples were examined with the
formol ethyl acetate sedimentation method for
helminth ova and protozoan
cysts . -
pubmed
High and low consumption of
soybeans as well as of
sunflower and
pumpkin seeds were associated with significantly reduced
breast cancer risk compared to no consumption ( OR = 0.83 , 95 % CI = 0.70 - 0.97 ; and OR = 0.66 , 95 % CI = 0.77 - 0.97 , respectively ) . -
pubmed
Our results provide evidence for a reduced
postmenopausal breast cancer risk associated with increased consumption of
sunflower and
pumpkin seeds and
soybeans . -
pubmed
Effect of adjuvant chemotherapy on survival of
patients with stage III
colon cancer diagnosed after age 75 years . -
pubmed
Genetic characterization and construction of an auxotrophic
strain of
Saccharomyces cerevisiae JP1 , a Brazilian industrial
yeast strain for
bioethanol production . -
pubmed
Yeast strains have acquired distinct characteristics that are the result of evolutionary adaptation to the stresses of industrial
ethanol production . -
pubmed
cerevisiae
strain isolated from a
sugarcane mill and is becoming increasingly popular for
bioethanol production in Brazil . -
pubmed
Emerging
infectious diseases (
EIDs ) pose a significant threat to
human health , economic stability , and biodiversity . -
pubmed
Here , we highlight the emergence of a zoonotic Henipavirus ,
Nipah virus , to demonstrate the interdisciplinary and macroecological approaches necessary to understand
EID emergence . -
pubmed
We aimed to investigated the serum miRNA profile in
pertussis patients and explored its potential as a novel diagnostic biomarker for
pertussis . -
pubmed
Among 664 different miRNAs analyzed using a miRNA array , 50 were overexpressed and 81 were underexpressed in the serum of
pertussis patients . -
pubmed
A panel of five miRNAs ( miR-202 , miR-342 - 5p , miR-206 , miR-487b , miR-576 - 5p ) was confirmed overexpressed in
pertussis patients ( p & lt ; 0.05 ) . -
pubmed
Risperidone - induced
paroxysmal perceptual alteration in a
child with
autism . -
pubmed
BACKGROUND : Hyperthermic intraperitoneal chemotherapy ( HIPEC ) is more and more used in the treatment of
patients with
peritoneal carcinomatosis (
PC ) of different primary
tumours . -
pubmed
However , survival of
patients with
PC is still poor . -
pubmed
MATERIALS AND METHODS : A model for
peritoneal carcinomatosis of colorectal origin was created by implantation of
tumour fragments (
HT29 ) in the abdomen of athymic
nude rats . -
pubmed
Ocular manifestations and visual functions in
patients with
Fanconi anaemia . -
pubmed
METHODS : Ten
patients with
FA , ages 8 - 17 years , underwent ophthalmological examinations , corneal , periocular and fundus photography , visual evoked potentials ( VEPs ) , visual fields and ocular motor and visual processing information tests . -
pubmed
Microcornea was present in 18 of 18 eyes , short axial lengths in six of six eyes , steep corneal curvatures in four of six eyes ,
ptosis in 14 of 16 eyes ,
short palpebral fissures in 15 of 16 eyes and
hypotelorism in three of seven
patients . -
pubmed
Eight
patients had
ocular motor dysfunction , while nine of 10
patients showed delay in visual processing skills . -
pubmed
CONCLUSION :
Patients with
FA can present with
microcornea ,
microphthalmia ,
ptosis ,
steep corneal curvatures , small optic discs ,
ptosis and
delay in visual processing skills . -
pubmed
Supplemental parenteral nutrition in
critically ill patients . -
pubmed
Different from classical
strain engineering approaches , this work was initiated to improve
E. - pubmed
To test whether structural integrity of this fronto - striato - thalamic circuit can account for
executive impairments in
TBI we automatically segmented the thalamus , putamen and caudate of 25
patients and 21 healthy controls and obtained diffusion weighted images . -
pubmed
A 77 - year - old
woman with Stage IV
gastric cancer was admitted to our hospital because of high
fever ,
poor appetite , and
abdominal pain during combined chemotherapy with
S-1 and
cisplatin (
CDDP ) . -
pubmed
BACKGROUND : Challenging anatomy for carotid artery access can result in a delay to achieve successful recanalization in
patients with
acute ischemic stroke . -
pubmed
In
patients , chronic treatment with
lithium leads to renal microcysts and
nephrogenic diabetes insipidus (
NDI ) . -
pubmed
Kidney microcysts were induced in male adolescent
rats by feeding dams with
lithium ( 50 mmol / kg
chow ) from postnatal days 7 - 34 . -
pubmed
OBJECTIVE : The purpose of this work was to review the diagnosis , management , and outcomes of
patients with perianal
Paget ' s disease . -
pubmed
PATIENTS : Sixty - five
patients with
perianal Paget ' s disease were included in the study ( 35 women [ 54 % ] ; median age at diagnosis , 66 years [ range , 60 - 72 years ] ; and 41 with invasive
disease/24 with noninvasive disease ) . -
pubmed
Synchronous
malignancies unrelated to the primary disease were noted in 5
patients with invasive disease and 3 with noninvasive disease . -
pubmed
Forty - one
patients ( 27 invasive and 14 noninvasive ) required multiple operations for
tumor clearance . -
pubmed
Untreated
brain arteriovenous malformation :
patient - level meta - analysis of
hemorrhage predictors . -
pubmed
We censored
patients at first treatment ,
death , last visit , or 10 - year follow - up , and performed stratified Cox regression analysis of time - to -
hemorrhage after evaluating hemorrhagic presentation , sex , age at diagnosis , deep venous drainage , and AVM size as predictors . -
pubmed
RESULTS : A total of 141
hemorrhage events occurred during 6,074
patient - years of follow - up ( annual rate of 2.3 % , 95 % confidence interval [ CI ] 2.0%-2.7 % ) , higher for ruptured ( 4.8 % , 3.9%-5.9 % ) than unruptured ( 1.3 % , 1.0%-1.7 % )
AVMs at presentation . -
pubmed
The structure - activity relationship of these compounds was investigated , leading to the identification of compound 28 , which demonstrated favorable pharmacokinetic properties in
mice and good antitumor activities in the
human glioma xenograft model in athymic
nude mice . -
pubmed
Transgenic
mice that express the
HCV core protein develop
HCC after the
steatosis stage and produce an excess of hepatic reactive
oxygen species ( ROS ) . -
pubmed
Taken together , these results indicate that
Ca ( 2 + ) uniporter - mediated mitochondrial accumulation of
iron exacerbates
hepatocyte toxicity caused by the
HCV core protein . -
pubmed
Erythropoiesis - stimulating agents did not act directly upon isolated
tumor cells to stimulate pathways known to promote proliferation or survival of
human tumor cells isolated from primary and metastatic
tumor tissues . -
pubmed
MicroRNA-150 protects the
mouse heart from
ischaemic injury by regulating cell
death . -
pubmed
For example , miR-150 is down - regulated in
patients with
acute myocardial infarction ,
atrial fibrillation , dilated and
ischaemic cardiomyopathy as well as in various
mouse heart failure (
HF ) models . -
pubmed
METHODS AND RESULTS : Here , we show that genetic deletion of miR-150 in
mice causes abnormalities in cardiac structural and functional remodelling after
MI . -
pubmed
Assessing the abundance , seasonal questing activity , and Borrelia and
tick - borne encephalitis virus (
TBEV ) prevalence of
Ixodes ricinus ticks in a
Lyme borreliosis endemic area in Southwest Finland . -
pubmed
and
tick - borne encephalitis virus (
TBEV ) prevalence were evaluated in a
Lyme borreliosis endemic area in Southwest Finland , Seili Island , where a previous study mapping tick densities was conducted 12 years earlier . -
pubmed
High levels of regulatory T cells in blood are a poor prognostic factor in
patients with
diffuse large B - cell lymphoma . -
pubmed
METHODS : Peripheral blood samples from 77
patients with
DLBCL and 30 healthy
volunteers were analyzed using flow cytometry immunophenotyping . -
pubmed
CONCLUSIONS : Changes in blood immune cells occur in
patients with
DLBCL . -
pubmed
METHODS : From January 1 , 2007 to December 31 , 2009 , 37
patients who had
Hartofilakidis type B developmental dysplasia of the hip underwent a primary total hip arthroplasty using a high hip center technique . -
pubmed
Four
patients continued to present with
Trendelenburg gait pattern at the last follow - up . -
pubmed
Patients with
ECRS present with thick mucus production , long - term
nasal congestion ,
loss of sense of smell , and intermittent acute exacerbations secondary to
bacterial infections . -
pubmed
Demographics of
tuberculosis of spine and factors affecting neurological improvement in
patients suffering from
tuberculosis of spine : a retrospective analysis of 312 cases . -
pubmed
On statistical analysis , although three groups of
patients with complete improvement , partial improvement and no improvement were similar in age , sex , radiological presentation , and co - morbidities and the presence of
pulmonary tuberculosis , they were significantly different with regard to the levels of vertebral involvement ,
AIS grade at presentation , bladder and bowel involvement and its duration . -
pubmed
CONCLUSIONS : In management of
patients suffering from
tuberculosis of spine , levels of vertebral involvement ,
AIS grade at presentation , bladder and bowel involvement and its duration significantly affect the final neurological improvement . -
pubmed
Abstract The principles of rational antibacterial therapy in
children for the
burn trauma were analyzed . -
pubmed
The results of the completed treatment of 808
children for the
burn trauma in a Combustiological Department of Municipal clinical hospital of City of Zaporozhye were studied . -
pubmed
Prescription of modern anticlostridial probiotics , containing stamms of
Lactobacillus rhamnosus R0011 and
Lactobacillus acedofilus R0052 , on background of continuing antibacterial therapy , have constituted the effective measure of prophylaxis for the antibiotic - associated
diarrhea , as the most frequent complication of antibacterial therapy . -
pubmed
Despite significant technological advances ,
rheumatoid arthritis remains an incurable disease with great impact on the life quality of
patients . -
pubmed
Letter in response to : Identifying risk in the use of
tumor markers to improve
patient safety . -
pubmed
In this study , 829 diverse compounds with
rat carcinogenicity were collected from Carcinogenic Potency Database ( CPDB ) . -
pubmed
Furthermore , the best binary and ternary classification models were used to estimate
carcinogenicity of
tobacco smoke components containing 2251 compounds . -
pubmed
There were more early - stage
cancer patients in U group than in M group . -
pubmed
Serosurvey of
Coxiella burnetii (
Q fever ) in
Dromedary Camels (
Camelus dromedarius ) in Laikipia County , Kenya . -
pubmed
We evaluated the seroprevalence of a significant zoonotic pathogen ,
Coxiella burnetii (
Q fever ) , among 334
camels from nine herds in Laikipia County , Kenya . -
pubmed
This study was conducted as a randomized clinical trial on 18
patients ( divided into two groups ) after surgical correction of
Acute Aortic Aneurysm (
AAA ) . -
pubmed
However , three of the five selected compounds ( 6 , 23 , and 26 ) exhibited relatively high
cytotoxicity in
mouse fibroblasts at micromolar concentrations . -
pubmed
The selected
thio - sugars are very promising compounds , thus making them candidates for further modifications that would decrease their
cytotoxicity against
eukaryotic cells without affecting their antimycobacterial potential . -
pubmed
In addition , they establish a
murine model for studying the potential impact of this
dysbiosis on host resistance and physiology . -
pubmed
METHODS : We retrospectively reviewed 86
patients with
HCC ( 35 female , 51 male ) managed in our institution between 2009 and 2014 . -
pubmed
SUBJECTS / METHODS : We fed C57BL6
mice a high - fat diet to generate
obesity and then switched the diet to a lower - fat diet to induce
weight loss . -
pubmed
We then measured circulating levels of
PGD2 in
obese patients before and after
weight loss and found that while elevated relative to lean subjects , levels of this metabolite did not decrease after significant
weight loss . -
pubmed
A 67 - year - old
man with
coronary artery disease and previous coronary underwent successful Guideliner reverse CART percutaneous coronary intervention of a chronic total occlusion of the right coronary artery . -
pubmed
Despite these dramatic findings , the
patient remained hemodynamically stable and
pain - free , with resolving ECG changes . -
pubmed
Anesthesia management of a
patient with a
femoral neck fracture and
hered - itary hemorrhagic telangiectasia . -
pubmed
Literature regarding anesthesia and perioperative management of such patients is limited , with no published papers for orthopedic surgery in
patients with
HHT . -
pubmed
CASE REPORT : An 82 - year - old
HHT female
patient with
femoral neck fracture was scheduled for hemiarthroplasty . -
pubmed
CONCLUSION :
Patients with
HHT require careful preoperative evaluation to identify and appreciate possible symptoms as well as to assess their pulmonary and cardiac function accurately . -
pubmed
Patients with advanced ALN
metastases were more likely to have a higher number ( & gt;=2 ) of positive LNs ( OR , 8.06 ; P = 0.015 ) on restaging MR imaging . -
pubmed
INTRODUCTION : The purpose of this study was to evaluate clinical outcomes in
children with asymptomatic
congenital lung malformations (
CLM ) who were initially managed nonoperatively . -
pubmed
Objective : To observe the effect of hyperbaric
oxygen therapy for the
inflammation of
rabbit nasal in postoperation period , to investigate the clinical feasibility of
hyperbaric oxygen therapy in reducing the inflammatory reaction and promoting mucosal healing in nasal recovery stage after surgery . -
pubmed
Aesthetic outcomes and morphological changes in chin parameters after mandibular distraction and subsequent advancement genioplasty in
patients with
mandibular micrognathia . -
pubmed
This study addressed lower facial third aesthetics in a consecutive series of
subjects with
micrognathia who underwent MDO and subsequent advancement genioplasty . -
pubmed
Pre - genioplasty cephalometric measurements showed that all
patients had a
deficient chin position and projection ; they were dissatisfied with their facial aesthetics . -
pubmed
In this study , we examined how
PHOSPHO1 deficiency might affect the healing and quality of
fracture callus in
mice . -
pubmed
Fractures were allowed to heal for four weeks and then the
mice were euthanized and their tibias analyzed using radiographs , micro - CT ( muCT ) , histology , histomorphometry and three - point bending tests . -
pubmed
This included 8
patients with mid - shaft tibial
fractures and 6 intact cadaveric legs . -
pubmed
PARTICIPANTS : A total of 104
patients complaining of
neck or arm pain with no prior surgical history and who had undergone a CNRB at an outpatient clinic from May 2015 to December 2017 were included . -
pubmed
The writing group reaffirmed the 2015 pediatric advanced life support guideline recommendation that either
lidocaine or
amiodarone may be used to treat pediatric
patients with
shock - refractory
ventricular fibrillation or pulseless
ventricular tachycardia . -
pubmed
Reply to the Editor- The site of origin of the
ventricular premature beat in a
patient with 2 different P - wave morphologies . -
pubmed
CONCLUSIONS : The observed mortality in the intubated
children 1 - 6 years old suffering from severe
TBI seemed to be higher than expected . -
pubmed
Unilateral Osteotomy of Lumbar Facet Joint Induces a
Mouse Model of Lumbar Facet Joint
Osteoarthritis . -
pubmed
The establish of
animal models highly mimicking the clinical conditions is a useful tool for the investigation of LFJ
OA . -
pubmed
However , the previously established
animal models damaged the LFJ structure directly , which did not demonstrate the effect of aberrant mechanical loading on the development of LFJ
osteoarthritis . -
pubmed
METHODS : In the present study , an
animal model for
LFJ degeneration was established by the unilateral osteotomy of LFJ ( OLFJ ) in L4/5 unit to induce the
spine instability . -
pubmed
Effect of
resveratrol on the radiosensitivity of
5 - FU in
human breast cancer MCF-7 cells . -
pubmed
OBJECTIVE : To analyze the clinical characteristics and drug resistance in
patients with non - tuberculous mycobacteria (
NTM ) pulmonary disease in Changsha Central Hospital of Hunan Province in recent three years . -
pubmed
Mycobacterium avium - intracellulare ( 56.21 % ) and
mycobacterium chelonae -
abscess ( 20.92 % ) were the majority . -
pubmed
We report here a case of an immunocompetent
patient suffering from recurrent epithelial
herpetic keratitis associated with the emergence of antiviral resistance . -
pubmed
Safety , effectiveness , and health care cost comparisons among elderly
patients with
venous thromboembolism prescribed
warfarin or
apixaban in the United States Medicare population . -
pubmed
We retrospectively summarized the clinical characteristics of
patients with
cesarean scar pregnancy and explored the advantages and disadvantages of fertility - preservation treatment method . -
pubmed
145
patients underwent transvaginal clearance , 33
patients underwent endoscopic surgery , and 26
patients underwent
uterine artery embolism . -
pubmed
Conclusion : Transvaginal clearance is an effective and relatively safe treatment option for
patients with
cesarean scar pregnancy . -
pubmed
Of note ,
patients whose biopsy is performed at a specialized musculoskeletal
tumor center benefit in terms of improved local
tumor control . -
pubmed
These data indicate that the mPFC is responsible for the social recognition deficit in the transgenic
mice , and provide new insight into potential therapies for
MECP2 duplication syndrome . -
pubmed
METHODS : In this study , 182
patients with
Alzheimer ( 125 women and 57 men ) were evaluated . -
pubmed
Ground - glass opacity on chest computed tomography in a young , athletic
man with
coronavirus disease 2019 - related
pneumonia without
hypoxemia . -
pubmed
The effect of
oxytocin vaginal gel on
vaginal atrophy in postmenopausal
women : a randomized controlled trial . -
pubmed
BACKGROUND : Around 90 % of postmenopausal
women are suffering from
vaginal atrophy . -
pubmed
This study aimed to evaluate the effect of
oxytocin vaginal gel on
vaginal atrophy among postmenopausal
women . -
pubmed
METHODS : This was a randomized controlled trial that was conducted on 96 postmenopausal
women who suffered from
vaginal atrophy . -
pubmed
After 8 weeks , 88.6 and 7.1 % of
women in the
oxytocin and placebo groups did not show the severe symptoms of
vaginal atrophy ( p = 0.001 ) . -
pubmed
The median
patient age was 61 yr and median preoperative
tumor size was 30 mm . -
pubmed
Fingolimod reduces salivary infiltrates and increases salivary secretion in a
murine Sjogren ' s model . -
pubmed
We thus examined in an
animal model of
SjS the effects of
Fingolimod (
FTY720 ,
Gilenya ) , which interferes with migration of lymphocytes to peripheral sites . -
pubmed
Oral
Fingolimod thus merits further consideration in the management of
SjS in
humans . -
pubmed
Impact of
SARS - CoV-2 Pandemic on "
Stroke Code " Imaging Utilization and Yield . -
pubmed
Increased Incidence of
Giant Cell Arteritis After Introduction of a Live
Varicella Zoster Virus Vaccine . -
pubmed
Background :
Varicella zoster virus (
VZV ) has been associated with
giant cell arteritis (
GCA ) . -
pubmed
The nutritional requirements of 43
strains of
Haemophilus influenzae isolated from clinical and normal flora sources were investigated . -
pubmed
Runt disease in suckling hybrid
mice : substrain differences and litter seriation . -
pubmed
Upon entry into the cytoplasm of irradiated
chicken embryo cells in slide chamber cultures infected over a 2 - h period , yolk sac - grown virulent ( Breinl
strain ) and attenuated ( E
strain )
Rickettsia prowazeki underwent indistinguishable reproducible intracellular growth cycles . -
pubmed
Frequency of
ahaptoglobinaemia ( ahp ) in adult population ( on the base of investigation of 4000 cases ) was found 0.225 per cent , in children ( on the base of investigation of 119
children younger than 2 years ) 0.94 per cent . -
pubmed
A 10 - year series of 100
patients with clinically undiagnosed
prostatic adenocarcinoma is presented . -
pubmed
In 50 per cent of these patients the
tumor was well differentiated and the survival was normal , while the remainder of the
patients had moderately to poorly differentiated
tumors and survival rates significantly less than normal . -
pubmed
The sera of 67
patients with
thymomas-43 with
myasthenia gravis (
thymoma(+ )
MG(+ ) ) and 24 without
myasthenia gravis (
thymoma ( + )
MG ( - ) ) from 5 Dutch centers were examined with the indirect immunofluorescence test for the presence of antibodies reacting with skeletal muscle ( AMA ) , thyroid tissue , gastric parietal cells , adrenocortex and antinuclear antibodies ( ANA ) . -
pubmed
The data were compared with those obtained in a group 83
MG patients in whom a
thymoma was excluded by histological verification (
thymoma ( - ) MG ( + ) ) and with 1106 controls from the normal population . -
pubmed
Patients with
MG and without antimuscle antibodies have no
thymomas : This rule is of practical value in the management of the
MG patient . -
pubmed
A total of 313
patients with childhood
acute leukemia received a combination of
vincristine ( 2 mg / m2 / week ) and
prednisone ( 60 mg / m2 / day ) ; 86 % of 276 evaluable
patients achieved a complete
bone marrow remission in a median of 35 days . -
pubmed
Between January 1 , 1971 and February 1 , 1974 , 31
patients have undergone laparotomy for staging of a
malignant lymphoma , Hobgkin or not . -
pubmed
Group A received
ivermectin 0.1 mg / kg orally at a single dose , the cure rates were 100 % , 3.8 % and 50 % for ascaris ,
hookworm and trichuris ,
infections respectively : group B received
ivermectin 0.2 mg / kg orally at a single dose , the corresponding cure rates were 95.5 % , 11.8 % and 76.5 % respectively ; group C received
pyrantel pamoate 10 mg / kg orally at a single dose , the corresponding cure rates were 95.5 % , 29.6 % and 31.6 % respectively . -
pubmed
Although the cure rates were very low for
hookworm infection in both group A and B , however , a number of adult worms of
Ancylostoma duodenale and
Necator americanus were expelled aster medication ; It indicates that
ivermectin has some effects on these two species of
human hookworm . -
pubmed
The current study traces the development of contractile cells in the nonmuscular segments of
rat lung microvessels in
hyperoxic pulmonary hypertension . -
pubmed
Associated anti -
epileptic therapy affected the
CBZ L / D ratio , which was significantly reduced in
patients on polytherapy as compared to
patients on monotherapy . -
pubmed
The study therefore suggests that routine monitoring of
CBZ serum levels is extremely useful , especially in the paediatric age group , and in
patients who require associated anti -
epileptic medication . -
pubmed
New strategies in antineoplastic therapy that have been applied during the last 5 years to
children with
malignant disease include the Goldic - Coldman hypothesis , new methods of drug delivery , reduction in
toxicity with prolonged intravenous infusions , shortening of maintenance therapy and techniques to improve the compliance of adolescents and older
children with prescribed therapy . -
pubmed
These new concepts of chemotherapy in developmental pharmacology to treat
cancers in
children are reviewed . -
pubmed
The 92
piglets were divided into the following 5 groups : swimmers with
infection ( S - I ; n = 19 ) ; swimmers without
infection ( S ; n = 19 ) ; control piglets with
infection ( K - I ; n = 21 ) ; controls without
infection , but direct ( K1 ; n = 16 ) or indirect contact ( K2 ; n = 17 ) with experimentally infected animals . -
pubmed
The experimental or spontaneous
infection ( direct or aerogenous
infection ) with
M. - pubmed
Contact
urticaria from
runner bean (
Phaseolus multiflorus ) . -
pubmed
[
Human dirofilariasis in Italy : a new palpebral case with spontaneous healing in Abruzzo ] . -
pubmed
One case of
human palpebral dirofilariasis by
Dirofilaria repens , in Abruzzo , is described . -
pubmed
Antimicrobial MIC data were obtained for 96
strains of
Staphylococcus haemolyticus and the following 11 antimicrobial agents :
methicillin ,
gentamicin ,
rifampin ,
fusidic acid ,
ciprofloxacin ,
vancomycin ,
teicoplanin ; three experimental glycopeptides , MDL 62,873 , MDL 62,208 , and MDL 62,224 ; and an experimental lipoglycopeptide ,
ramoplanin . -
pubmed
Recordings were made in normal
sinus rhythm ( NSR ) ( 5 beats each in 8/8
patients ) , during
ventricular tachycardia (
VT ) ( 38 beats with 7 morphologies in 3
patients ) and during
premature ventricular contractions (
PVCs ) ( 20 beats with 8 morphologies in 6
patients ) . -
pubmed
Intervals between the intrinsic deflection of the two ventricular electrograms ranged from 0 to 91 ms ( mean of 26 ms ) during NSR , from 13 to 141 ms ( mean of 66 ms ) during
VT , and from 10 to 72 ms ( mean of 40 ms ) during PVCs and were reproducible within each
patient for each type of rhythm . -
pubmed
The use of protein preparations and fresh frozen plasma is believed essential in intensive plasmapheresis in
patients with
immunomediated disorders and
DIC syndrome , respectively . -
pubmed
Mice transgenic for a
vasopressin -
SV40 hybrid oncogene develop
tumors of the endocrine pancreas and the anterior pituitary . -
pubmed
A possible model for
human multiple endocrine neoplasia type 1 . -
pubmed
The possible relationship between the
endocrine tumor syndrome found in the
vasopressin -
SV40 transgenic
mice and familial
human multiple endocrine neoplasia is discussed . -
pubmed
[ Treatment of
patients with stage I
non - seminomatous testicular tumors with general orchiectomy ] . -
pubmed
A group of 24
patients with
non - seminomatous germ cell tumors of the testis in clinical stage I were followed in a prospective study in order to evaluate the strategy of " surveillance " consisting of regular check - up and administration of chemotherapy in the case of progression of the disease . -
pubmed
A continuous cell line of
chimpanzee lymphocytes producing an antibody specifically associated with non - A ,
non - B hepatitis (
NANB ) was established . -
pubmed
Peripheral blood lymphocytes of a
chimpanzee convalescent from experimental
infection with
NANB hepatitis were transformed in vitro by
Epstein - Barr virus infection into
lymphoblastoid cell lines . -
pubmed
Supernatants of the cell cultures were screened by immunofluorescence for antibody activity against the liver tissue of a
chimpanzee with
NANB hepatitis . -
pubmed
In addition , examinations of serial liver biopsy specimens obtained from 2
chimpanzees experimentally infected with
NANB hepatitis demonstrated that the antibody reacted with the biopsies obtained during the preacute , acute , and
chronic hepatitis , but not with those obtained before inoculation , early incubation period , or during
convalescence . -
pubmed
Immunoelectron microscopy revealed that the antibody reacted with the microtubular aggregates identical to those previously described in a patient and
chimpanzees with
NANB hepatitis . -
pubmed
Ninety - eight
patients died ( overall mortality 3.2 per cent ) and intraperitoneal
sepsis was a related factor in twelve ( 0.4 per cent ) . -
pubmed
A case of
osteomyelitis due to
Kingella kingae is presented to illustrate the insidious onset and indolent course typical of
bone infections caused by this organism . -
pubmed
Initial therapy with an
aminopenicillin such as
ampicillin in addition to antimicrobial drugs for
Staphylococcus aureus should be effective in resolving
bone and joint infections in children . -
pubmed
Comparative developmental and phenotypic properties of altered hepatocyte foci and
hepatic tumors in
rats . -
pubmed
Previous investigations in this laboratory have provided evidence that histochemically detectable altered hepatocyte foci and
hepatic tumors appearing in
rats given a single neonatal treatment with a low dose of carcinogen followed by chronic dietary
phenobarbital administration are developmentally independent . -
pubmed
The developmental and phenotypic properties of the hist(+)/morph(- ) foci , hist(+)/morph(+ ) foci , and
hepatic tumors were compared in
rats initiated once neonatally with different doses of
diethylnitrosamine and promoted with dietary
phenobarbital from weaning . -
pubmed
Care study --
Clostridium difficile : enteric spread of
infection . -
pubmed
Wound pieces taken from 3 - 6 sites at a time during surgical treatment of the
wound in 10
patients with thermal
burns involving 25 - 50 % of the body surface area , were examined by electron - microscopic radioautography and bacteriologically . -
pubmed
The
burn wounds were found to contain not only live ( RNA - synthesizing ) bacteria but also replicating ( DNA - synthesizing ) bacteria , and to be heterogeneous in terms of bacterial seeding ( the largest numbers being present in the scab and the smallest , in the granulation tissue ) , but not of bacterial species ; these were represented in all layers by mixed populations (
Pseudomonas aeruginosa , pathogenic
Staphylococcus ,
Proteus ) , although the deep layers contained more pathogenic and more virulent subpopulations than the more superficial ones . -
pubmed
Healing of horizontal circumferential
periodontal defects following regenerative surgery in
beagle dogs . -
pubmed
Regenerative surgery of
dog teeth with reduced periodontal support was undertaken to determine : if new connective tissue attachment could be predictably attained back to the level of the cemento - enamel junction ; and to what extent the new attachment would be accompanied by bone regeneration ,
root resorption , and
ankylosis . -
pubmed
A morphometric analysis of the inflammatory infiltrate cells of the stroma and adjacent tissue of
adenocarcinomas of the rectum was performed in 40
patients . -
pubmed
Monteggia fracture -
dislocations in
children . -
pubmed
Thirty - three
Monteggia fracture -
dislocations occurring in
patients aged 2 to 15 years were reviewed . -
pubmed
A mild
hyperextension deformity at the elbow noted on follow - up of
patients with
anterior dislocation of the radial head seemed to support the theory that the
injury is caused by
hyperextension . -
pubmed
A new classification of
Monteggia fracture - dislocations in
children is proposed . -
pubmed
In short - term cultures of thymocytes from
tetanus toxoid - immunized
mice , the addition of 1 ng of toxoid generated the release of a soluble factor which was capable of enhancing the immune response to a heterologous immunogen . -
pubmed
[ Production of stomach and
pancreatic cancer in the
guinea pig using
methylnitroso - urea and
methylnitroso - urethane ] . -
pubmed
[ Changes in the diameter of some cell
strains transformed by
adenovirus and
SV 40 virus , studied in vitro and in vivo ] . -
pubmed
[ Contractility of the
human uterus with a cesarean section
scar ( author 's transl ) ] . -
pubmed
[
Cataract extraction in
patients with
hypertension ] . -
pubmed
Vaginal discharge and histological change of the ovary and the uterus in the
rat . -
pubmed
[ Treatment and chemoprevention of
brucellar abortion in
cattle with
4 - 4 ' , diaminodiazoaminobenzol ] . -
pubmed
Evaluation of radiosensitivity in the cyclic phases of
mouse fibrosarcoma cells in vitro . -
pubmed
In the clinical study , four
glioma patients were treated by intravenous administration of
Cisplatin 10 mg / sqm for 5 days q 4 weekly . -
pubmed
Three
patient with
intracranial embryonal carcinoma were treated by
cisplatin . -
pubmed
In a study of 30 consecutive
patients with
constrictive pericarditis diagnosed by clinical , radiological , and echocardiographic criteria 21 ( 70 % ) were found to have pulsatile
hepatomegaly . -
pubmed
Thus this poorly appreciated clinical finding appears to be present in a high proportion of
patients with
constrictive pericarditis . -
pubmed
[ Power in the periphery of several aspheric eyeglasses for
aphakic patients ] . -
pubmed
[ Quantitative content of Bacteroides in normal
human intestines and in
dysbacteriosis ] . -
pubmed
In the fed state ,
obese rats showed more rapid clearance of the label from the bloodstream and , in both fed and fasted states , greater uptake into retroperitoneal and parametrical fat pads than lean
rats . -
pubmed
Obese rats showed proportionally less uptake into heart and liver . -
pubmed
Comparison of highly basic
cyanogen bromide peptides from
strains of
southern bean mosaic virus . -
pubmed
Forty - nine
patients ( 29.3 % ) developed 83
postoperative complications . -
pubmed
OBJECTIVE : This report reviews the case of a missed
cervical spine fracture in a
patient presenting for chiropractic manipulative therapy . -
pubmed
CLINICAL FEATURES : A 65 - yr - old
woman presented to a chiropractic office for examination and treatment of
cervical spine injuries suffered in a deceleration type motor vehicle accident . -
pubmed
This case demonstrates that chiropractors should be extremely cautious in initiating manipulative therapy in those
patients having sustained previous
cervical spine trauma and who have had prior X - rays that have been reported normal . -
pubmed
Each
animal was chronically instrumented with an electromagnetic flow probe on the ascending aorta , a
strain gauge pressure transducer implanted in the apex of the left ventricle ( LV ) , and electrocardiogram leads anchored to the chest wall and LV . -
pubmed
Enhanced
gamma - aminobutyric acid - mediated responses in nucleus tractus solitarius of
hypertensive rats . -
pubmed
In both groups of
hypertensive rats the pressor response to injection into the nucleus tractus solitarius of the
GABA uptake blocking drug
nipecotic acid was significantly greater compared with control
rats ( P & lt ; .01 in each model ) . -
pubmed
The controversy extends to the
nonobese diabetic (
NOD )
mouse that develops disease similar to
human insulin - dependent diabetes mellitus . -
pubmed
Autoreactive T cells are present , functional , and can transfer
diabetes to appropriate NOD - recipient
mice . -
pubmed
OBJECTIVE : This study investigated these delay periods and the compliance with therapy in
children with
tuberculosis . -
pubmed
DESIGN : During the study period there were 49
children with probable and 123 with confirmed
pulmonary tuberculosis ( WHO criteria ) . -
pubmed
Subjects with
cutaneous facial photodamage were randomised to treatment with
tretinoin ( 62 ) or vehicle ( 63 ) cream . -
pubmed
Dietary vitamin B12 deficiency in a
patient with
multiple sclerosis . -
pubmed
The authors present a case of
dietary vitamin B12 deficiency in a
patient with
multiple sclerosis . -
pubmed
A simple schemata for evaluating
patients for
vitamin B12 deficiency is included as a clinical aid for physicians . -
pubmed
Effect of maternal
paraquat administration on the
fetal ductus arteriosus in the
rat . -
pubmed
The ductus arteriosus ( DA ) in the fetal
rat was calibrated using a whole - body freezing method , 3 hr after maternal treatment with
paraquat at a dose of 25 mg / kg of
body weight on days 19 - 21 of gestation . -
pubmed
Seventy - one
Escherichia coli strains isolated from diarrhoeic weaned
rabbits from different areas of France were tested for the presence of DNA sequences specific for the
EPEC ,
EHEC ,
DAEC and
EAggEC strains and 16 of them were tested for pathogenicity in animal experiments . -
pubmed
Clinically comparable , randomized sites of 8
patients with progressive adult
periodontitis were treated 4 times in intervals of approximately 4 months . -
pubmed
Analysis of
Dolichos biflorus - reactive axons revealed that these axons coursed randomly , with no evidence of their selective
fasciculation , within the olfactory nerve . -
pubmed
Oral administration of
nitrendipine ( 5 or 10 mg , 3 h before induction of anaesthesia ) was able to attenuate the
hypertensive response to tracheal intubation in ASA 1
patients under light anaesthesia . -
pubmed
We propose this pharmacological technique with supplementary doses of
opioids and/or
benzodiazepines for the management of
patients with
hypertension or
coronary artery disease . -
pubmed
This suggests use of the
CMV promoter for gene therapy targeted at macrophages , as , for example , in the treatment of
lysosomal storage disorders such as
Gaucher disease . -
pubmed
METHODS : Serum samples were obtained at 7 to 18 weeks of gestation from 58
women whose fetuses were known to be affected by
Down ' s syndrome , 32 whose fetuses were affected by
trisomy 18 , and 438 whose fetuses were normal , and the samples were analyzed for each marker . -
pubmed
Regional chamber stiffness and myocardial stiffness were assessed using the end -
diastolic pressure - length relationship which was modified by stepwise infusion and withdrawal of 200 mL of the
animals ' own blood during baseline , 45 min low flow
ischemia ( systolic bulge ) , and 60 min after the onset of reperfusion . -
pubmed
Evaluation of the monitoring of
papular dermatitis lesions in slaughtered
swine to assess sarcoptic
mite infestation . -
pubmed
We investigated the association between the presence of
papular dermatitis and
sarcoptic mite infestation in
pigs slaughtered in southern Minnesota . -
pubmed
Following dehairing , a sample of 30
pigs from each of 50 herds was inspected for
papular dermatitis lesions . -
pubmed
Herd infestation with
sarcoptic mange was determined by recovery of mites from ear scrapings of slaughtered
pigs and also by survey of producer opinion . -
pubmed
Generalized lesions occurred in 36.7 % of
pigs from herds confirmed to be infested , compared with 0.4 % of pigs in herds confirmed free from
mange . -
pubmed
Our date indicate that monitoring of
dermatitis lesions in slaughtered
pigs might be a useful test for
sarcoptic mange in the Midwest , USA . -
pubmed
In this study , a modified version of ASEPSIS ( a
wound scoring system ) has been prospectively evaluated in 1000
patients undergoing cardiac surgery . -
pubmed
Twenty - one
patients ( 2.1 % ) had an
infected sternal wound . -
pubmed
Developmental
toxicity of inhaled
N - methylformamide in the
rat . -
pubmed
The developmental
toxicity of
N - methylformamide (
MMF ) , an industrial chemical intermediate used in the production of agrichemicals , was examined in pregnant
rats . -
pubmed
Maternal
toxicity was evident in
dams exposed to 50 or 150 ppm ; one dam exposed to 150 ppm died on Day 14 G ( considered to be treatment - related ) and dams in the 50 and 150 ppm groups exhibited concentration - related clinical findings . -
pubmed
Phase II trial of intravenous endotoxin in
patients with
colorectal and non - small cell lung cancer . -
pubmed
We report the immunological and clinical results of a phase II trial with intravenously administered highly purified endotoxin (
Salmonella abortus equi ) in
patients with advanced
cancer . -
pubmed
15
patients with
non - small cell lung cancer and 27 with
colorectal cancer were entered into the study . -
pubmed
Divergent selection for
body weight and yolk precursor in
Coturnix coturnix japonica . -
pubmed
[ Acquisition of ability to metastasize by spontaneous
tumors under the effect of
metastazin 1 in transgenic
animals ] . -
pubmed
[
Nootropil in the treatment of
disorders of the higher mental functions in
patients with an
ischemic stroke ] . -
pubmed
47
patients with
acute ischemic stroke were treated with
nootropil (
pyracetam ,
UCB , Belgium ) from the first day of the disease ( 12 g , intravenously , by drops during 2 weeks , then 4.8 g , per os ) on the background of basic therapy . -
pubmed
There was observed more pronounced positive dynamics of functions of damaged hemisphere in
patients with localisation of
ischemic focus in left hemisphere . -
pubmed
The conclusion was made that
nootropil can be prescribed for the
patients with hemispheric
ischemic stroke and especially for the
patients with alterations of cerebral circulation in system of internal carotid artery including such disturbances on the background of
insufficiency of circulation in vertebrobasilar system . -
pubmed
Dietary
omega-3 polyunsaturated fatty acids plus
vitamin E restore
immunodeficiency and prolong survival for severely ill
patients with generalized
malignancy : a randomized control trial . -
pubmed
BACKGROUND : The aim of the current prospective , randomized control study was to investigate the effect of dietary
omega-3 polyunsaturated fatty acids plus
vitamin E on the immune status and survival of well - nourished and malnourished
patients with generalized
malignancy . -
pubmed
METHODS : Sixty
patients with generalized solid
tumors were randomized to receive dietary supplementation with either
fish oil ( 18 g of
omega-3 polyunsaturated fatty acids ,
PUFA ) or placebo daily until
death . -
pubmed
CONCLUSIONS :
Malnutrition appears to be an important predictor of survival for
patients with end stage
malignant disease . -
pubmed
Omega-3 polyunsaturated fatty acids had a significant immunomodulating effect and seemed to prolong the survival of malnourished
patients with generalized
malignancy . -
pubmed
Patients were stratified by Karnofsky performance status and presence or absence of
liver metastases . -
pubmed
To evaluate the contribution of reactive
nitrogen species to
inflammation by asbestos ,
Fischer 344 rats were exposed to
crocidolite or chrysotile asbestos by inhalation to determine whether increases occurred in
nitric oxide (
NO . ) -
pubmed
BACKGROUND AND OBJECTIVE : Two - dimensional
polyacrylamide gel electrophoresis ( 2 - D PAGE ) is a new method which can be used to study cryoprecipitates from the sera of
cryoglobulinemic patients . -
pubmed
DESIGN AND METHODS : Sixty consecutive
patients affected by
cryoglobulinemic syndrome with mixed cryoglobulins were included in the study . -
pubmed
All
patients were evaluated for
cutaneous , articular , hepatic , renal and nervous involvement . -
pubmed
However ,
RA resistance arises during
RA treatment of
APL patients . -
pubmed
Antitumor activity of
ZD1694 (
tomudex ) against
human head and neck cancer in
nude mouse models : role of dosing schedule and plasma
thymidine . -
pubmed
Among 62 consecutive
patients with their first
lacunar stroke and 202 normal controls , we found that
hypertension ( p & lt ; 0.001 ) , smoking ( p = 0.001 ) , and
aortic arch atheroma ( p = 0.006 ) were independently associated with an increased risk of
lacunar stroke . -
pubmed
METHODS : The clinical and epidemiological features of 102
children with
extra - pulmonary tuberculosis , diagnosed between 1982 and 1998 at P & amp ; A Kyriakou Children 's Hospital were reviewed . -
pubmed
The source of
infection was disclosed in 48
patients . -
pubmed
Miliary tuberculosis developed in infants ,
lymphadenitis and
meningitis in preschool
children , and
pleural effusion and
skeletal tuberculosis in older children . -
pubmed
A case report of the use of
magnesium sulphate during anaesthesia in a
patient who had adrenalectomy for
phaeochromocytoma . -
pubmed
INTRODUCTION :
Patients with
phaeochromocytoma have haemodynamic instability during adrenalectomy . -
pubmed
OUTCOME : The
patient had to be given
phentolamine and
sodium nitroprusside to control the severe
hypertension . -
pubmed
Following the operation , the
patient suffered from transient right
abducens nerve palsy , which persisted for 3 months . -
pubmed
Enterohemorrhagic
Escherichia coli (
EHEC ) O157 : H7 causes serious
diarrhea and
hemolytic uremic syndrome in
humans . -
pubmed
Body composition changes in
patients with
anorexia nervosa after complete weight recovery . -
pubmed
SUBJECTS : : Ten female
patients with
anorexia nervosa ( age at baseline : 19.7+/-5.8 y ) were studied both when undernourished (
body mass index ,
BMI 14.8+/-1.3 kg/ m(2 ) ) and after the achievement of a
BMI & gt;18.5 kg / m(2 ) . -
pubmed
Mapping studies in
patients with drug - refractory paroxysmal
atrial fibrillation identified potentials from the ostia of pulmonary veins as a main source of triggers that initiate
atrial fibrillation . -
pubmed
Correlation of blood -
glucose control with oxidative metabolites in plasma and vitreous body of
diabetic patients . -
pubmed
This study investigated
patients with
diabetic retinopathy for evidence of oxidative metabolites in plasma and the vitreous body , correlating these values with blood -
glucose control . -
pubmed
METHODS : The study comprised 136
patients suffering from proliferative
diabetic retinopathy . -
pubmed
[ Defects of the low urinary tract as a cause of recurrent
urinary tract infection in
girls ] . -
pubmed
462
girls aged 1 month--15 years with recurrent
urinary tract infection were diagnosed in the Outpatient Clinic of Mother and Child Institute during 1985 - 1992 and 1999 - 2000 years period . -
pubmed
We present a detailed case report of a 25 - year - old
man with
PVNS of the hip . -
pubmed
Silent
lupus nephritis (
SLN ) was investigated in 42 renal asymptomatic
patients and compared with 49 untreated
patients with overt
lupus nephropathy (
OLN ) . -
pubmed
Forty - one out of the 42 ( 97.6 % )
patients had
SLN according to histopathological findings . -
pubmed
We conclude that , in our series ,
SLN was highly prevalent in renal asymptomatic
patients with otherwise
systemic lupus erythematosus . -
pubmed
[ Specific localisation of
human cytomegalovirus nucleic acids and proteins in
human colorectal cancer ] . -
pubmed
[ Blood and cerebrospinal fluid findings in
molimina crurum nocturna ( including
restless legs ) ] . -
pubmed
Inhaled
corticosteroids with long acting
beta 2 - mimetics have become the mainstay of therapy for
patients with
asthma . -
pubmed
Are anticonvulsants a satisfactory alternative to opiate analgesia in
patients experiencing
pain with
Guillain - Barre syndrome ? -
pubmed
We report a
patient being followed for
chronic renal insufficiency by renal ultrasound in whom a renal mass was detected . -
pubmed
Tacrolimus ointment is safe and effective for short- and long - term treatment of
atopic dermatitis (
AD ) in pediatric and adult
patients . -
pubmed
CASE REPORT : A 51 - year - old
patient undergoing surgery for a right postcentral
glioma was first submitted to phase reversal of somatosensory potentials for intraoperative localization of the central sulcus . -
pubmed
[ Optic nerve damage in
multiple sclerosis patients ] . -
pubmed
PURPOSE : The aim of the work was to catch the type of damage of optic nerve in the group of
patients with
multiple sclerosis . -
pubmed
MATERIAL AND METHODS : The examinations were held on 77 eyes of 40
patients with
multiple sclerosis . -
pubmed
Among them 11
patients had previous
optic neuritis , 29 have not problems with vision . -
pubmed
CONCLUSIONS : Psychophysical tests enable early diagnosis and monitoring of
optic nerve damage in
multiple sclerosis patients . -
pubmed
The authors report the results of a phase IIa immunotherapy trial of AN1792(QS-21 ) in
patients with mild to moderate
Alzheimer disease (
AD ) that was interrupted because of
meningoencephalitis in 6 % of immunized
patients . -
pubmed
METHODS : This randomized , multicenter , placebo - controlled , double - blind trial of IM AN1792 225 microg plus the adjuvant QS-21 50 microg ( 300
patients ) and saline ( 72
patients ) included
patients aged 50 to 85 years with probable
AD , Mini - Mental State Examination ( MMSE ) 15 to 26 . -
pubmed
RESULTS : Following reports of
meningoencephalitis ( overall 18/300 [ 6 % ] ) , immunization was stopped after one ( 2
patients ) , two ( 274
patients ) , or three ( 24
patients ) injections . -
pubmed
Methicillin - resistant
Staphylocosis aureus (
MRSA ) is an emerging
infection in patients with
cystic fibrosis (
CF ) . -
pubmed
Experimental
autoimmune uveitis (
EAU ) can be induced in susceptible
mice by immunization with retinal
antigens . -
pubmed
Giving that a large number of transgenic and KO
mice are available in B6 background , an improved
uveitis model in B6
mouse should assist the determination of pathogenesis of disease and identify
molecules that can be targeted by new therapies . -
pubmed
Comparison of indices of
vitamin A status in
children with
chronic liver disease . -
pubmed
The most accurate way to assess
vitamin A status in
children who have
cholestasis is unknown . -
pubmed
Children with chronic
cholestatic liver disease ( n = 23 ) and
noncholestatic liver disease ( n = 10 ) were studied . -
pubmed
Ten
cholestatic patients were identified as
vitamin A - deficient based on the relative dose response ( RDR ) . -
pubmed
In conclusion ,
vitamin A deficiency is relatively common in
children who have chronic
cholestatic liver disease . -
pubmed
After characterization of the natural spread of
necrosis - inducing
Bean yellow mosaic potyvirus ( family Potyviridae , genus Potyvirus ,
BYMV(N ) ) , nonpersistently transmitted from clover ,
Trifolium repens L. , to an adjacent field of
snap bean ,
Phaseolus vulgaris L. , in western Oregon , we established a study site enabling us to investigate the virus reservoir , to observe en masse transmission of
BYMV(N ) to bean plants , and to identify aphid species associated with virus spread . -
pubmed
Percutaneous radiofrequency ablation of
renal tumors : midterm results in 16
patients . -
pubmed
PURPOSE : To evaluate the outcome of 16
patients after percutaneous radiofrequency ablation of
renal tumors . -
pubmed
Only one
patient had evidence of local recurrent
tumor . -
pubmed
Human Papillomavirus (
HPV ) vaccines will likely have an impact as a preventive strategy for
cervical cancer . -
pubmed
Screening for
precancerous lesions can not be discontinued because vaccination will not protect against
HPV types not included in the first generation of vaccines . -
pubmed
Moreover , protection for the target types , 16 and 18 , which are responsible for most cases of cervical
precancerous lesions and
cancer , and 6 and 11 , which are responsible for a substantial proportion of low - grade lesions , can not be expected to be absolute , and the likely implementation of
HPV vaccination in young women will not impact older groups initially . -
pubmed
Cervical cancer control programs will need to be re - evaluated because the addition of
HPV vaccination will make the existing approach of high - frequency screening by cytology too costly and inefficient for most public health budgets . -
pubmed
Another advantage of using
HPV testing as a primary screening tool is the opportunity to create
infection registries that can link test results from the same women over time , thus allowing an efficient and low - cost strategy to monitor long - term protection among vaccinated women . -
pubmed
BACKGROUND : Endoscopic treatment of intractable chronic anterior and lateral exertional
compartment syndromes of the lower leg in
athletes is reported anecdotically only in six
patients . -
pubmed
No complications were seen following endoscopic anterior and lateral compartment decompression , while two
patients following deep posterior compartment release underwent open revision surgery due to
hemorrhage . -
pubmed
There were no
postoperative complications due to
vascular injuries in all further
patients who were operated without tourniquet . -
pubmed
METHODS : We studied 12
subjects with
pulmonary alveolar proteinosis , 61 healthy control
subjects , and 12 control
subjects with either
cystic fibrosis or
end - stage liver disease . -
pubmed
The accumulation of complex
hepatitis B virus (
HBV ) variants with internal in - frame deletions in the C gene in immunosuppressed renal transplant recipients is associated with a severe course of the
infection leading to
end - stage liver disease (
ESLD ) . -
pubmed
There were no differences in remissions , time to remission ,
relapse rate , or time to relapse between daily- and alternate - day - treated
patients . -
pubmed
At follow up ,
patients with an episode of
ARF had higher serum
creatinine than those without
ARF . -
pubmed
Four
patients progressed to
ESRD . -
pubmed
These
patients were less likely to have responded to
steroids and more likely to have
FSGS on repeat renal biopsy . -
pubmed
ARF occurs in a significant number of adult
MCD patients and may leave residual
renal dysfunction . -
pubmed
Few
patients progress to
ESRD . -
pubmed
URINE
CHLORIDE CONCENTRATION IN
PATIENTS WITH
CUSHING ' S SYNDROME . -
pubmed
A clinical epidemiological study in 2169
patients with
vertigo . -
pubmed
METHODS : Retrospective study on 2169
patients with
vertigo ( male 883 , female 1286 , 7 - 90 years old ) of the past 20 years . -
pubmed
Peripheral , central , and unclassified
vertigo took up 33.8 , 17.2 and 26.8 % of
patients , respectively , while
vertigo of unknown origin was around 22.2 % . -
pubmed
Spontaneous urinary
calcium oxalate crystallization in
hypercalciuric children . -
pubmed
We assessed the associations between spontaneous
CaOx crystallization based on the Bonn Risk Index ( BRI ) , urinary pH ,
calciuria ,
oxaluria , and
citraturia in 140 Caucasian
patients with
hypercalciuria , aged 4 - 17 years , and compared the findings with those in 210 normocalciuric controls . -
pubmed
Of the 140
hypercalciuric patients , 58 had
renal stones , and 82 had recurrent
erythrocyturia ,
renal colic , or
urinary obstructive symptoms - but without stones . -
pubmed
Determination of the BRI in
children with
hypercalciuria may improve the risk assessment of
kidney stones . -
pubmed
We excluded
patients presenting with an acute ST - elevation
myocardial infarction (
MI ) within & lt ; or = 24 hours , hemodynamic instability /
shock , thrombolytic therapy within & lt ; or = 7 days , or
renal insufficiency . -
pubmed
Ozone ameliorates
methotrexate - induced
intestinal injury in
rats . -
pubmed
Thus , this study was designed to investigate the efficacy of
ozone therapy in the prevention of
Mtx - induced
intestinal injury in
rats . -
pubmed
[ The use of
atorvastatin in
patients with
rheumatoid arthritis with
hyperlipidemia ] . -
pubmed
MATERIAL :
Patients with
RA ( n=50 ) were divided into 2 groups . -
pubmed
CONCLUSION : The data obtained allow to recommend the use of
atorvastatin for long term management of
hyperlipidemia in
patients with
RA . -
pubmed
IVUS detected
CAV in 17 of 30
patients ( 57 % ) and in 41 of 110 coronary segments ( 37 % ) . -
pubmed
We found only 14
children reported to have bilateral
vocal fold paralysis associated with
CMT , and only 1 of these cases was associated with
CMT type 1 . -
pubmed
Cell culture processes offer an attractive alternative to conventional
chicken egg - based
influenza vaccine production methods . -
pubmed
Production in serum - free suspension of
HEK-293 cultures resulted in high titers of infectious
influenza viruses for different subtypes and variants including
A / H1 ,
A / H3 and B
strains . -
pubmed
BACKGROUND : Surgical excision can cure most
patients with
malignant melanoma of the skin . -
pubmed
METHODS : Data from 2487
patients with
malignant melanoma and primary treatment between 1978 and 1997 at the Department of Surgery or the Department of Dermatology , University Hospital Erlangen , Germany , were prospectively collected in the
Melanoma Registry of the University Hospital Erlangen . -
pubmed
RESULTS : Overall survival was found to be significantly worse in older
patients ,
men ,
melanoma of the head or trunk , and
melanoma with high pT and pN categories . -
pubmed
In 523
patients ,
relapse from
malignant melanoma was observed after a median of 24 months . -
pubmed
Among
patients with
recurrences , young age and low pT and pN categories proved to be independent factors that prolonged the
disease - free interval . -
pubmed
Despite wide distribution of this virus , designated
Calbertado virus ,
strains demonstrate a high degree of nonstructural protein 5 nucleotide ( & gt ; 90 % ) and
amino acid ( & gt ; 97 % ) identity . -
pubmed
The ecology and geographic range of
Calbertado virus warrants further study because it may potentially influence transmission of mosquito - borne flaviviruses , including important
human pathogens such as
West Nile and Saint Louis encephalitis viruses . -
pubmed
Despite advances in treatment , the prognosis of a
patient with
amyloidosis is still poor and depends upon the underlying disease , and the type and degree of dysfunction of the involved organs . -
pubmed
Although the roles of mast cells ( MCs ) are essential in many inflammatory and
fibrotic diseases , their role in
Trypanosoma cruzi - induced
cardiomyopathy is unexplored . -
pubmed
Although these data show that MCs are important in controlling
acute infection , we observed MC apoptosis in the cardiac tissue and peritoneal cavity of untreated
mice . -
pubmed
METHODS : The 32
patients with
Type 2 diabetes and 15 healthy controls were enrolled into the study . -
pubmed
All three
strains produced a
rhamnolipid that differs in structure from
Pseudomonas aeruginosa rhamnolipids and exhibits excellent surfactant properties . -
pubmed
Proteomic analysis of urine in medication - overuse
headache patients : possible relation with
renal damages . -
pubmed
Various epidemiologic investigations proved that different drug types could cause
nephrotoxicity , particularly in chronic
patients . -
pubmed
The aim of the present work was to analyze , by a proteomic approach , the urinary protein profiles of
MOH patients focusing on daily use of NSAIDs , mixtures and
triptans that could reasonably be related to potential
renal damage . -
pubmed
In conclusion , this preliminary proteomic study allowed us to define the urinary protein pattern of
MOH patients that is related to the abused drug . -
pubmed
According with the obtained results , we believe that the risk of
nephrotoxicity should be considered particularly in
MOH patients who abuse of NSAIDs . -
pubmed
The type
strain is
A8036(T ) ( = DSM 45508(T ) = KCTC 19868(T ) ) . -
pubmed
Patients with
neuromuscular disorders are often complicated by progressive
scoliosis . -
pubmed
We must pay attention to
spinal deformity in
patients with
Duchenne muscular dystrophy , especially after they lose the ability to walk because
spinal deformity frequently develops . -
pubmed
MATERIALS AND METHODS :
Urothelial bladder carcinoma patients ( n=38 , including 31
men and 7
women ) and healthy controls ( n=25 , including 20
men and 5
women ) were included in the study . -
pubmed
gammadelta T cells are also able to respond to local
inflammation and consequently regulate the pathogenesis of
autoimmune disorders and development of
tumors in
mice and
humans . -
pubmed
Among the 30
patients , 21
patients survived ( 70 % ) and 9 patients with community - acquired
pneumonia (
CAP ) died ( 30 % ) . -
pubmed
The 21 surviving patients included 17
patients with acute respiratory distress secondary to
CAP and 4
patients with
asthmatic crisis upon admission to the ICU . -
pubmed
After admission , all
patients progressed to
sepsis and showed an increase in blood
glucose . -
pubmed
It is therefore important to measure continuously
glucose concentrations , as well as the numbers of neutrophils and lymphocytes in
critically ill patients with
hyperglycemia . -
pubmed
Ciguatera toxicity is a
poisoning from consuming reef fish that had fed on dinoflagellates such as
Gambierdiscus toxicus found along coral reefs . -
pubmed
Its abnormal expression may be involved in the
oncogenesis of
human malignancies such as
lung cancer . -
pubmed
However , even though intrathecally delivered synthetic omega - conotoxin MVIIA from
Conus magnus (
ziconotide [
Prialt ] ) has been approved for the treatment of
chronic pain in
humans , its mode of delivery and narrow therapeutic window have limited its usefulness . -
pubmed
In vivo efficacy in
rat models of inflammatory and
neuropathic pain was demonstrated by a representative compound from this series . -
pubmed
The study objective was to determine the prevalence of
vitamin D deficiency , risk factors for its presence , and potential association with clinically relevant outcomes in
critically ill children . -
pubmed
Data and biological samples from 326
critically ill children up to 17 years of age were available for analysis . -
pubmed
CONCLUSIONS : This study provides evidence that
vitamin D deficiency is both common among
critically ill children and associated with greater severity of
critical illness . -
pubmed
Recent studies have shown that downregulation of the microRNA miR-124 occurs in several types of
human cancer , suggesting a
tumor suppressive function of miR-124 . -
pubmed
Application of stent placement or nasojejunal feeding tube placement in
patients with malignant
gastric outlet obstruction : a retrospective series of 38 cases . -
pubmed
Patients treated for
primary adrenal insufficiency (
PAI ) are at risk of
steroid over - replacement , which may affect their skeleton . -
pubmed
Lumbar spine
osteoporosis and
osteopenia were found in 12 and 31
patients , respectively , whereas in femoral neck : in 5 and 33
individuals . -
pubmed
METHODS : We analyzed 150 consecutive
patients who underwent elective
gastric cancer surgery at the Shiga University of Medical Science Hospital ( Shiga , Japan ) from 1997 to 2009 ; of these , most surgeries ( n = 100 ) were performed 2008 onwards . -
pubmed
The
patient characteristics and surgery - related factors between two groups ( with and without
infection ) were compared by the paired t - test and chi(2 ) test , including preoperative ADN levels , postoperative day 1 ADN levels , and ADN ratio ( postoperative ADN levels / preoperative ADN levels ) as baseline factors . -
pubmed
RESULTS : Sixty
patients ( 40 % ) experienced
postoperative infections . -
pubmed
Among the historical control group , the main causes of graft failure were
patient deaths ( 68 % ) , which were mostly caused by
liver diseases . -
pubmed
The results shows that miRNA profile changes in
HIV-1 seropositive individuals , and the 56 differentially expressed miRNAs may play important role during
HIV infection . -
pubmed
NSCs have been demonstrated to be very useful in grafts into the
mammalian central nervous system to investigate the exploitation of
NSC for the therapy of
neurodegenerative disorders in
animal models of
neurodegenerative diseases . -
pubmed
Reply to Errera and Campbell : No , low salinity
shock does not increase
brevetoxins in
Karenia brevis . -
pubmed
Effectiveness of
Laminaria jam enriched with
chromium has been investigated in ambulatory
patients with
metabolic syndrome . -
pubmed
Differential effects of opioid - related ligands and NSAIDs in
nonhuman primate models of acute and inflammatory
pain . -
pubmed
RATIONALE : Carrageenan - induced
hyperalgesia is a widely used
pain model in
rodents . -
pubmed
However , characteristics of carrageenan - induced
hyperalgesia and effects of analgesic drugs under these conditions are unknown in
nonhuman primates . -
pubmed
RESULTS : Tail injection of carrageenan produced long - lasting thermal
hyperalgesia in
monkeys . -
pubmed
The opioid - related ligands displayed differential pharmacological properties in regulating
hyperalgesia and acute nociception in the same
subjects . -
pubmed
OBJECTIVE : To examine
pain and biopsychosocial correlates over time for
women with persistent
postsurgical pain after surgery for
endometriosis . -
pubmed
METHODS : Cross - sectional study of
women who underwent any
endometriosis surgery between 2003 and 2006 . -
pubmed
Following surgery ,
patients completed validated questionnaires ( Short - Form McGill
Pain Questionnaire , 12 - item Short - Form Health Survey , Beck Depression Inventory , Coping Strategies Questionnaire catastrophizing subscale ) . -
pubmed
Cystic fibrosis (
CF ) patients are at high risk of colonization of the airways by a number of fungi , including the emerging opportunistic fungus
Geosmithia argillacea . -
pubmed
Diffusion - weighted magnetic resonance imaging to evaluate microvascular density after transarterial embolization ablation in a
rabbit VX2
liver tumor model . -
pubmed
This information allows clinicians to better predict and manage
communication impairment in
children with
cerebral palsy . -
pubmed
Exploring the relationship between preferences for high fat foods and efficacy of the ketogenic and modified Atkins diets among
children with
seizure disorders . -
pubmed
PURPOSE : Previous research has indicated that
children with
seizures may prefer high fat foods - a preference compatible with ketogenic and modified Atkins dietary therapies . -
pubmed
Toward a comparative retrospective analysis of
rat and
rabbit developmental toxicity studies for pharmaceutical compounds . -
pubmed
Genetic characterization of
Vibrio vulnificus strains isolated from oyster samples in Mexico . -
pubmed
Vibrio vulnificus strains were isolated from oysters that were collected at the main seafood market in Mexico City . -
pubmed
An Erb 's Engram is a common
debility that develops in recovering
children with
Erb ' s palsy . -
pubmed
The purpose of this study was to investigate the effect of kinesiotaping over the deltoid and the forearm on the development of proper upper extremity function in
children recovering from
Erb ' s palsy . -
pubmed
Thirty
patients with
Erb ' s palsy participated for 3 months in this study and were equally divided into two groups ; control group A and study group B. -
pubmed
A
posterior fossa intradiploic epidermoid cyst was removed from the calvarium of an otherwise healthy 34 - year - old
woman after work up for
dizziness and
blurry vision . -
pubmed
Although this would appear to affect a small number of patients , the impact of these changes are broad , leading to an increased use of advanced imaging , a debate around the management of
patients previously diagnosed with
smouldering myeloma , changed terminology and clinical trial design and an extension of the use of biomarkers . -
pubmed
We sought to define trends for
IMV in the United States and assess for disease - specific variation for 3 common causes of
respiratory failure :
pneumonia ,
heart failure (
HF ) , and
chronic obstructive pulmonary disease (
COPD ) . -
pubmed
METHODS : We calculated national estimates for utilization of nonsurgical
IMV cases from the Nationwide Inpatient Sample from 1993 to 2009 and compared trends for
COPD ,
HF , and
pneumonia . -
pubmed
CLINICAL CASE : A 17 - year - old
patient with a progressively growing
tumour in the right inguinoscrotal region . -
pubmed
Effect of Chinese herbal medicines for nourishing yin , supplementing qi , and activating blood on reproductive endocrine activity and immune functions in
patients with primary
Sjogren ' s syndrome . -
pubmed
OBJECTIVE : To investigate the effect of Chinese herbal medicines for nourishing yin , supplementing qi , and activating blood on the reproductive endocrine - immune network and its mechanisms in
patients with primary
Sjogren ' s syndrome (
pSS ) . -
pubmed
METHODS : Seventy
pSS patients were randomly assigned to two groups using a randomized digital table : the integrative therapy group ( 36 cases ) and the control group ( 34 cases ) . -
pubmed
Chinese herbal medicines for nourishing yin , supplementing qi , and activating blood combined with Western medicine could improve the therapeutic effect by regulating the reproductive endocrine - immune network in
pSS patients . -
pubmed
Incidence and predictors of
interstitial lung disease (
ILD ) in Thai
patients with early
systemic sclerosis : Inception cohort study . -
pubmed
RESULTS : One hundred and thirteen
patients ( 66 females and 89 diffuse cutaneous
SSc [
dcSSc ] ) with a mean + - SD age of 53.4 + - 8.4 years and mean disease duration of 12.9 + - 10.3 months at cohort entry were enrolled . -
pubmed
At enrollment ,
patients with
dcSSc had a higher prevalence of
ILD ( 78.7 % vs. 45.8 % , p = 0.002 ) , and a higher total HRCT score ( 10.3 + - 9.5 vs. 4.4 + - 5.6 , p = 0.001 ) compared with limited cutaneous
SSc (
lcSSc ) . -
pubmed
Efficacy of Probiotic
Escherichia coli Nissle 1917 in
Patients with
Irritable Bowel Syndrome : a Double Blind Placebo - controlled Randomized Trial . -
pubmed
139 confirmed
IBS patients were included into the study , and were given probiotic
E.coli Nissle 1917 for 6 weeks . -
pubmed
49(35.3 % ) of the
patients were
diarrhea - predominant . -
pubmed
Patients with
constipation - predominant
IBS showed no response to the probiotic ; while patients with
diarrhea -
constipation mixed
IBS showed unfavorable response to the probiotic in the need for
strain to pass a motion compared to the placebo ( p=0.03 and 0.02 at weeks 4 and 6 , respectively ) . -
pubmed
CONCLUSION : probiotic therapy with
E.coli Nissle 1917 was not able to induce significant improvement in the symptoms of patients with non - categorized
IBS . -
pubmed
The effect of
D - galactosamine on lean and
steatotic rat hepatocytes in primary culture . -
pubmed
The aim of our work was to compare the effect of
D - galactosamine (
GalN ) on primary cultures of lean and steatotic
rat hepatocytes isolated from intact and
fatty liver , respectively . -
pubmed
Some reported effects of
SPA pretreatment on
septic shock in
mouse models but there is no study which reports the role of
SPA pretreatment on the infected incision . -
pubmed
The
bacterial suspension was gradually dripped and embrocated onto the incision surface to make the
wound infection model . -
pubmed
Before making the
wound infection model for 48 hours and 24 hours ,
mice were retreated with SPA via intraperitoneal injection . -
pubmed
RESULTS : A 1 - mL
bacterial suspension can be utilized to make the
wound infection model of BALB / c
mouse lower limb . -
pubmed
SPA pretreatment can reduce the inflammatory reactions in
wound methicillin - resistant
Staphylococcus aureus infection mouse model and the best pretreatment dose is 1 mg / kg . -
pubmed
A 1 - mg / kg
SPA pretreatment can also reduce the inflammatory reactions in
wound various
bacterial infection mouse models . -
pubmed
CONCLUSION :
SPA pretreatment can effectively decrease the infected severity of a
wound infected by various bacteria in a
BALB / c mouse model . -
pubmed
Metabonomic profiles delineate potential role of
glutamate -
glutamine cycle in db / db
mice with
diabetes - associated cognitive decline . -
pubmed
In this study ,
( 1 ) H nuclear magnetic resonance - based metabonomics and immunohistochemistry was used to explore key metabolic alterations in hippocampus of
type 2 diabetic db / db
mice with
cognition decline in order to advance understanding of mechanisms underlying the pathogenesis of the disease . -
pubmed
Several
tricarboxylic acid cycle intermediates including
succinate and
citrate were reduced in hippocampus of db / db
mice with
cognition decline . -
pubmed
CONCLUSIONS : Our results suggest that the development of
diabetes - associated cognition decline in db / db
mice is most likely implicated in a reduction in energy metabolism and a disturbance of
glutamate -
glutamine shuttling between neurons and astrocytes in hippocampus . -
pubmed
CONCLUSION : Early results of a large series of a modern TAA system demonstrate improvement in
patient satisfaction , quality of life , activity , and
pain for
patients with end - stage
ankle arthritis . -
pubmed
PURPOSE OF REVIEW : The Gleason grading system provides important information for guiding
prostate cancer patients ' management and prognostication . -
pubmed
Predictors of survival in
patients who underwent video - assisted thoracic surgery
talc pleurodesis for
malignant pleural effusion . -
pubmed
BACKGROUND :
Patients with
malignant pleural effusion have a limited life expectancy . -
pubmed
METHODS : We examined the medical records of all consecutive
patients with
malignant pleural effusion who underwent VATS
talc pleurodesis from 2006 to 2008 at the Samsung Medical Center . -
pubmed
RESULTS : During the study period , 91
patients underwent VATS
talc pleurodesis to treat
malignant pleural effusion . -
pubmed
The postoperative respiratory complication rate was 11 % ( 10
patients ) , and included
pneumonia ( 9 ) and
acute respiratory distress syndrome ( 4 ) . -
pubmed
When
PC3 cells were injected into proximal tibiae in
nude mouse , severe trabecular and cortical bone destruction and subsequent
tumor growths were detected . -
pubmed
The aim of this report is to introduce an on - going prospective phase II clinical trial performed to evaluate the preventive effectiveness of
Lactobacillus vaginal suppositories for prevention of recurrent
cystitis . -
pubmed
Patients enrolled in this study are administered vaginal suppositories containing the GAI 98322
strain of
Lactobacillus crispatus every 2 days or 3 times a week for one year . -
pubmed
In
SCI groups ,
rats underwent Th9 - 10
spinal cord transection followed by oral application of vehicle ,
naftopidil ( 20 mg / kg / day ) or
tadalafil ( 2 mg / kg / day ) for 1 , 2 , 4 , 8 , and 12 weeks . -
pubmed
Green tea consumption reduced the risk of
PC but the results were statistically borderline . -
pubmed
OBJECTIVE : The purpose of this study was to determine the safety and outcomes of VT & gt;1RFA in
patients with
structural heart disease . -
pubmed
METHODS :
Patients with
structural heart disease undergoing VT RFA at 12 centers with data on prior RFA history were included . -
pubmed
& gt;1RFA vs 1RFA
patients did not differ with regard to age ( 62 + - 13 years vs 62 + - 13 years ) , left ventricular ejection fraction ( 33 % + - 13 % vs 34 % + - 13 % ) , or sex ( 88 % vs 87 % men ) , but they more often were
nonischemic ( 53 % vs 41 % ) , had implantable cardioverter - defibrillator
shocks ( 70 % vs 63 % ) or
VT storm ( 38 % vs 33 % ) , and had been treated with
amiodarone ( 55 % vs 48 % ) or & gt;=2 antiarrhythmic drugs ( 22 % vs 14 % ) . -
pubmed
Leptomeningeal carcinomatosis in a young
patient with obstructive
colorectal signet - ring cell adenocarcinoma . -
pubmed
We present the case report of a twenty - five - year - old Moroccan male
patient who suffered from
leptomeningeal carcinomatosis related to a
signet - ring cell carcinoma of the rectum . -
pubmed
This case shows the tendency of
colorectal signet - ring cell carcinomas to cause
leptomeningeal metastasis , even in young
patients . -
pubmed
METHODOLOGY : A prospective randomized trial involving screening of 1000 pregnant
women for
gestational diabetes mellitus was conducted . -
pubmed
Women diagnosed with '
gestational diabetes ' were followed in an antenatal clinic , and incidence of
GDM and maternal and fetal outcome between two groups were analyzed using SPSS . -
pubmed
RESULTS : During period 1 , we recruited older
patients ( average 65 vs 64 years ) , less often women ( 19 vs 26 % ) and having less severe
airflow obstruction ( mean FEV1 48 vs 54 % ) . -
pubmed
A very low calorie ketogenic diet improves
weight loss and quality of life in
patients with adjustable gastric banding . -
pubmed
In twenty
patients ( GROUP A ) we observed a stop in
weight loss so we divided this
patients into two groups . -
pubmed
CONCLUSIONS : KD can improve the
weight loss and quality of life in
patients who underwent LAGB and failed at losing more weight allowing a
weight loss comparable to that obtained with a further calibration and it is useful to avoid drastic calibrations and their collateral effects . -
pubmed
BACKGROUND : About 25 % of
hypotensive ELBW
infants are refractory to intravascular volume expansion and inotropic drugs ( VI ) and require
hydrocortisone ( HC ) . -
pubmed
ELBW
infants with refractory
hypotension (
RH ) are clinically and biochemically indistinguishable from those who respond to VI . -
pubmed
OBJECTIVE : Early identification and differentiation of ELBW
infants susceptible to
steroid dependent
hypotension from those who respond to inotropic medications . -
pubmed
METHODS : In a retrospective study the ante- and postnatal clinical characteristics of ELBW
infants who received
hydrocortisone ( HC ) for refractory
hypotension (
RH ) were compared to those who responded to volume - inotropes ( VI ) . -
pubmed
In this study , we explored its predictive value for treatment response and survival in
metastatic renal - cell carcinoma (
mRCC )
patients . -
pubmed
Pasteurella multocida ,
Mannheimia haemolytica and
Trueperella pyogenes are three bacterial pathogens closely associated with the
bovine respiratory disease complex ( BRDC ) . -
pubmed
Cochlear Dysfunction is not Common in
Human Meningioma of the Internal Auditory Canal . -
pubmed
HYPOTHESIS :
Cochlear dysfunction is not common in
human meningioma of the internal auditory canal . -
pubmed
METHODS : Retrospective analysis of cochlear histopathology in five unoperated and five operated
meningiomas of the internal auditory canal identified after screening
human temporal bone collections from three academic medical centers . -
pubmed
CONCLUSIONS : Substantial
cochlear damage in
human meningioma of the internal auditory canal is not common . -
pubmed
Rotavirus G (
RVG )
strains have been detected in a variety of avian species , but RVG genomes have been published from only a single pigeon and two
chicken strains . -
pubmed
Two
turkey RVG
strains were identified and characterized , one in a hatchery with no reported health issues and the other in a hatchery with high embryo / poult mortality . -
pubmed
Low nucleotide percentage identities ( 31.6 - 87.3 % ) occurred among the
pigeon and
chicken RVG
strains . -
pubmed
The epidemiology of
RVG in avian flocks and the pathogenicity of the two different
RVG strains should be further investigated to understand the ecology and impact of
RVG in commercial poultry flocks . -
pubmed
Methods : This was a retrospective study of 153
patients who underwent Ivor Lewis esophagectomy for
squamous cell carcinoma between January 2008 and December 2016 . -
pubmed
Postoperative complications occurred in 17 ( 32.1 % ) and 23 ( 37.1 % )
patients in the HIL and OIL groups , respectively ( P=0.573 ) ; in - hospital mortality rates were 3.8 % and 8.1 % , respectively ( P=0.337 ) . -
pubmed
Bacteria and biofilms are likely contributory but secondary drivers of
inflammation . -
pubmed
We present a case of profound
hyponatremia of 102 mmol / L in a
patient who required emergent operative repair for
bowel obstruction . -
pubmed
This is the first case to our knowledge that demonstrates a perioperative fluid and
desmopressin treatment strategy to prevent overly rapid changes of
sodium concentration in a
patient with severe
hyponatremia . -
pubmed
CASE PRESENTATION : An 81 - year - old
man was referred to our hospital with a 5 - month history of
dysphagia . -
pubmed
The
patient was treated by thoracoscopic esophagectomy with three - field lymph node dissection and gastric tube reconstruction via a posterior mediastinal approach , under the diagnosis of
esophagogastric junctional cancer ( T3N0M0 , stage IIA ) . -
pubmed
Histopathological examination revealed two distinct components , namely , a
neuroendocrine carcinoma component and an
adenocarcinoma component , and the
patient was diagnosed as having mixed
adenoneuroendocrine carcinoma (
MANEC ) . -
pubmed
Thereafter , the
tumor became even more aggressive , and the
patient died 8 months after the surgery . -
pubmed
CONCLUSIONS : We report a
patient with
MANEC of the esophagogastric junction . -
pubmed
Close attention should be paid to such
patients , as
MANEC can be a highly aggressive
tumor , showing rapid progression . -
pubmed
The efficacy of both the EOs to disrupt the preformed biofilms of various
MRSA strains was determined by Confocal Laser Scanning Microscopy ( CLSM ) and Scanning Electron Microscopy ( SEM).The EOs were further able to reduce the Extracellular polymeric substance ( EPS ) and slime synthesis the two factors of the biofilm assemblage . -
pubmed
METHODS : Sixty pregnant
women with
pulpitis were divided into the first , second and third trimester . -
pubmed
MI was induced in a
rat model by ligation of the left anterior descending artery . -
pubmed
OBJECTIVE : To provide a comparative quantitative summary of surgical complications and postoperative
seizure freedom associated with invasive extra - operative presurgical techniques in pediatric
patients . -
pubmed
At the time of the last postoperative visit , a greater percentage of pediatric
patients achieved
seizure freedom in the SEEG studies ( SEEG : 66.5 % , 95 % CI 58.8 - 73.4 ; SDG : 52.1 % , 95 % CI 43.0 - 61.1 ) . -
pubmed
A 70 - year - old
woman with a background of
portopulmonary hypertension , managed with
sildenafil and oral diuretics , and
cirrhosis , presented with acute on chronic
haemorrhoidal bleeding ,
iron deficiency anaemia and worsening right
heart failure . -
pubmed
We found that
MERS - CoV infection induced pyroptosis and over - activation of complement in
human macrophages . -
pubmed
Although population expansion of
cowpea bruchid (
Callosobruchus maculatus ( Fabricius ) ) could be temporarily arrested when exposed to 2 %
O2 , this insect could survive extended periods of
hypoxia and continue its normal development if normoxic conditions resumed . -
pubmed
Early Experience With New Generation Deep Brain Stimulation Leads in
Parkinson ' s Disease and Essential
Tremor Patients . -
pubmed
Participants treated with antenatal sGC exhibited comparable levels of hair
cortisol ,
cortisone ,
dehydroepiandrosterone (
DHEA ) and
cortisol /
DHEA ratios compared to those of mothers who had been admitted to hospital for
pregnancy complications , but had never received sGC therapy and controls from physiological pregnancies . -
pubmed
High drug loading efficiency and sustained release of
doxorubicin from
Cy5 - functionalized
p ( HEMA - ran - GMA ) nanoparticles enabled effective inhibition of the
MCF-7 human breast cancer derived cell line . -
pubmed
The purpose of this study was to evaluate achievement of three motor milestones ( pull - to - standing , cruising and independent walking ) in two groups of
clubfoot patients treated at two experienced institutes respectively with the PM and FM . -
pubmed
A Pilot Study on the Effects of
l - Carnitine and
Trimethylamine - N - Oxide on Platelet Mitochondrial DNA Methylation and
CVD Biomarkers in Aged
Women . -
pubmed
Terlipressin for the treatment of
septic shock in
adults : a systematic review and meta - analysis . -
pubmed
BACKGROUND :
Catecholamines are the first - line vasopressors used in
patients with
septic shock . -
pubmed
OBJECTIVES : To investigate the immediate effects of forearm and/or wrist orthoses on outcome measures of
pain and function in
individuals with
lateral elbow tendinopathy . -
pubmed
DESIGN : Systematic review METHODS : Four electronic databases were searched to identify randomised controlled trials reporting the immediate effects of forearm and/or wrist orthoses on
pain and function in
individuals with
lateral elbow tendinopathy . -
pubmed
Intradetrusor
onabotulinumtoxinA injections ameliorate
autonomic dysreflexia while improving lower urinary tract function and
urinary incontinence - related quality of life in
individuals with
cervical and upper thoracic spinal cord injury . -
pubmed
All the isolates were evaluated for their
cytotoxic effects against a small panel of cultured
human cancer cell lines (
HeLa ,
A-549 ,
MDA - MB-231 ,
SKOV3 ,
Huh-7 , and
HCT-116 ) , and some of them exhibited
cytotoxicities with IC50 values ranging from 1.5 to 10.0 muM. -
pubmed
In the current study , we aimed to compare the long - term outcome of TACE + RT to that of RT alone in
patients with local advanced
HCC with MVI . -
pubmed
Methods : In this retrospective study , 148 treatment - naive
patients of
HCC with MVI were enrolled . -
pubmed
Two
patients ( 4.1 % ) experienced radiation - induced
liver disease (
RILD ) , and one ( 2.0 % ) experienced RT - related
gastrointestinal ( GI ) bleed in the TACE + RT groups . -
pubmed
Nine
patients ( 9.1 % ) experienced
RILD , and two ( 2.0 % ) experienced RT - related
GI bleed in the RT groups . -
pubmed
There is a distinct lack of literature surrounding the therapeutic use of nbUVB in
eczema in
children and especially in children with higher skin phototypes ( III to VI ) . -
pubmed
METHODS : We undertook a retrospective review of
children aged 18 years and under with
atopic eczema who had undergone nbUVB in our department between January 1st 2011 and December 31st 2017 . -
pubmed
CONCLUSION : We have demonstrated that nbUVB is a safe , well tolerated and efficacious form of treatment for
children with
atopic eczema . -
pubmed
METHODS : After initial diagnosis by ultrasound , 124 BI - RADS - US type 4
patients with 130 lesions were examined by contrast - enhanced ultrasound ( CEUS ) and were classified again before surgery according to five contrast - enhanced
malignancy imaging features : inhomogeneous enhancement , peripheral ring - like enhancement , expansive enhancement , internal filling defects , and surrounding radioactive convergence . -
pubmed
Visual - Attentional Load Unveils Slowed Processing Speed in
Multiple Sclerosis Patients : A Pilot Study with a Tablet - Based Videogame . -
pubmed
Fifty - one
patients with
MS (
pwMS ) , classified as having no
cognitive impairment in classic paper - and - pencil tests , and 20 healthy controls ( HC ) underwent the videogame tasks ; reaction times ( RTs ) and accuracy were recorded . -
pubmed
The in vivo analysis showed that after injection ,
L - EGCG - Mn exhibited a higher MRI signal compared to
Gd - DTPA in
H22 tumor - bearing
mice ( p < .05 ) . -
pubmed
High - density surface electromyography to assess motor unit firing rate in
Charcot - Marie - Tooth disease type 1A patients . -
pubmed
OBJECTIVE : The aim of this study was to elucidate the characteristics of the motor unit ( MU ) firing rate in
Charcot - Marie - Tooth disease type 1A (
CMT1A )
patients and its longitudinal change using high - density surface - electromyography ( surface - EMG ) and MU decomposition analysis . -
pubmed
METHODS : Nineteen
patients with
CMT1A and 21 force - matched healthy controls prospectively underwent surface - EMG recording of the vastus lateralis muscle during ramp - up and sustained contractions on performing isometric knee extension . -
pubmed
In
CMT1A patients , follow - up measurements were performed one year after the baseline . -
pubmed
Comparison of IFRs and clinical variables between
CMT1A patients and controls at the baseline and between the baseline and after one year in
CMT1A patients was performed . -
pubmed
RESULTS : Mean IFRs of MUs were lower in
CMT1A patients than in controls . -
pubmed
In
CMT1A patients , mean IFRs at 0 - 10 seconds of sustained contraction were significantly decreased over one year ( from 8.06 to 7.52 pps ; p = 0.027 ) , whereas the disease severity score and MVC of knee extension did not change over time . -
pubmed
CONCLUSION :
CMT1A patients had a lower individual MU firing rate . -
pubmed
SIGNIFICANCE : The MU firing rate is a potential short - term biomarker of
axonal damage in
CMT1A patients . -
pubmed
A phenotype - specific analysis of model performance was afforded by the annotations included in the St. Petersburg INCART
Arrhythmia database CONCLUSION : The five features this novel algorithm employed allowed our ventricular ectopy detector to obtain high precision on previously unseen subjects and databases SIGNIFICANCE : Our ventricular ectopy detector will be used to study the relationship between
premature ventricular contractions and adverse
patient outcomes such as
congestive heart failure and
death . -
pubmed
Clinical and sural nerve biopsy findings are described in four
hypothyroid patients with manifestations of a diffuse
peripheral neuropathy . -
pubmed
In one
patient , signs of the
peripheral neuropathy comprised the leading symptomatology of the underlying
metabolic disorder . -
pubmed
Dystrophic and degenerative changes in axons of all fiber classes and the presence of clusters of thinly myelinated small fibers suggest that
neuroaxonal degeneration and incomplete regeneration may represent the major pathogenetic mechanism of the
neuropathy in these
hypothyroid patients . -
pubmed
for the two components of
weight loss in the
mouse testis for fast neutrons relative to X - rays . -
pubmed
The " return " of
influenza A ( HINI ) virus after 20 years of absence raised the question of the sources and mechanisms of emergence of epidemic
influenza viruses and , particularly , of a new HINI virus (
A / USSR / 90 / 77 ) . -
pubmed
Two alternative hypotheses answer this question differently : the new HINI virus is the progeny of old HINI viruses retained in the
human population or is a newly arising recombinant between numerous
human and animal
influenza viruses circulation in the biosphere . -
pubmed
The blood
glucose lowering properties of the two
hydrazones were most manifest in fasted
guinea pigs ,
diabetic mice and
rats with
streptozotozin diabetes . -
pubmed
Exaggerated natriuresis in response to hypertonic saline infusion occurs with great regularity in
patients with documented previous attacks of
poststreptococcal glomerulonephritis . -
pubmed
In all
patients , extracellular fluid volume decreased during
sodium restriction , as judged by
weight loss , cumulative negative
sodium balance , small decreases in measured plasma volume , and appropriate increases of PRA and plasma
aldosterone concentration . -
pubmed
A comparison of
Salmonella dublin infection in normal and endotoxin - tolerant
mice . -
pubmed
Changes in general haemodynamics and renal function during exercise in
patients with
arterial hypertension . -
pubmed
Basic haemodynamic parameters were measured in 58
men in various stages of essential
hypertension , 18
patients with
hypertensive form of
chronic glomerulonephritis , and 23 practically healthy persons during graded exercise in the supine position on a bicycle ergometer for 30 minutes . -
pubmed
During exercise , the
systolic pressure rose in all persons investigated , whereas the
diastolic pressure markedly increased only in
patients with arterial
hypertension . -
pubmed
Renal blood flow and glomerular filtration decrease during exercise , both in healthy untrained persons and in
patients with
arterial hypertension . -
pubmed
In
patients in late stages of essential
hypertension and in those with
glomerulonephritis , the above parameters decrease more markedly and at lower exercise intensity than in healthy persons . -
pubmed
Moreover , although
CAPD patients seem to have better control of serum
phosphate concentration than hemodialysis
patients , the need for
aluminum - containing
phosphate binders ( ACPB ) may still be present . -
pubmed
In a prospective study meant to investigate the evolution of RO , we obtained 79 bone biopsies in 29
uremic patients ( 20 male , 9 female ; age 25 - 59 , mean 46 ) . -
pubmed
The highest bone
Al content was found among
patients with predominant
osteoid bone disease . -
pubmed
Also in
CAPD ,
patients consuming
ACPB are at risk of bone
Al accumulation despite the low
Al levels in the dialysate . -
pubmed
Replantation of an autoclaved , autogenous humerus in a
patient who had
chondrosarcoma . -
pubmed
A 33 - year - old
woman who was a
chronic alcohol abuser and had bilateral
visual loss was found to have
megaloblastic anemia with
thrombocytopenia . -
pubmed
Comparative evaluation of the immune status of congenitally athymic and euthymic
rat strains bred and maintained at different institutes : 1 . -
pubmed
We performed a comparative evaluation of the immune status , focused on the T - cell system , of euthymic
rat strains in which the nude mutation had been introduced . -
pubmed
Proteoglycans from the swarm
rat chondrosarcoma . -
pubmed
Proteoglycan aggregates were extracted from Swarm
rat chondrosarcoma tissue in the native state and compared with proteoglycan aggregates isolated dissociatively with 4 M
guanidine HCl . -
pubmed
Three
SMMX - resistant
strains of
B. - pubmed
[ Occurrence of
subdural hematoma closely associated with
danazol administration in a
patient with refractory
ITP ] . -
pubmed
It is strongly suggested that
danazol should be very carefully administered in
ITP patients with serious
bleeding tendency . -
pubmed
As reports become available on
human gastroenteritis caused by the atypical or novel rotaviruses , this technique presents an added advantage in that it can detect both group A and
non - group A rotaviruses . -
pubmed
Portal hypertension ameliorates
arterial hypertension in spontaneously
hypertensive rats . -
pubmed
Systemic hemodynamic effects of portal
hypertension in arterial
hypertension and their relationship to serum
bile acid levels were investigated using spontaneously
hypertensive rats 2 and 15 weeks after partial portal vein ligation ( SHR - PVL ) or sham operation ( SHR - SH ) and normotensive controls . -
pubmed
Animal data show that
noradrenaline deficiency results in scattered attention . -
pubmed
The cortical motor areas are relatively spared from neuro - degenerative changes in normal aging and in
AD /
SDAT and this might provide a neuroanatomical basis for the elderly 's and mildly to moderately demented
patients ' success in memory performance when motor action is involved . -
pubmed
This is an illustrative case of a
patient with
neuroleptic malignant syndrome whom we believe is the first described in the world 's literature to have this
syndrome on three occasions , each time after having received a different neuroleptic agent . -
pubmed
10 stable
asthmatics , 9
females and 1 male , all on regular inhaled bronchodilators and
steroid treatment , were studied following prior assessment of reversibility . -
pubmed
The hemodynamic pattern in
patients with
cirrhotic liver disease shows a hypercirculatory state , with elevated cardiac output and decreased systemic vascular resistance . -
pubmed
[ Do converting enzyme inhibitors give a better protection against
cerebral vascular complications in
hypertensive patients ? ] -
pubmed
Structural rearrangement of the
retinoblastoma gene in
human breast carcinoma . -
pubmed
Structural changes of the
human retinoblastoma gene have been demonstrated previously in
retinoblastoma and some clinically related
tumors including
osteosarcoma . -
pubmed
The histology findings of pre - clinical
neoplasia of the cervix at cone biopsy were compared with the previous colposcopic assessment in fifty - eight
patients . -
pubmed
A 25 - year - old white
man presented with acute
multiple sclerosis manifested by right
blindness , difficulty urinating , and
paresthesias and
weakness of both legs . -
pubmed
We describe a 68 - year - old
woman with a benign
hemangioma that presented clinically as a very large ovarian mass . -
pubmed
Curare and
pancuronium have multiple effects on previously undepressed
rat diaphragm ; these include
depression of transmitter output and prolongation of the refractory period of prejunctional structures . -
pubmed
[
Optic nerve injury in a
patient with
osteogenesis imperfecta tarda ] . -
pubmed
In a
patient with
myasthenic syndrome neuro - muscular transmission was characterised by
depression and facilitation . -
pubmed
Hyperprolactinaemia was induced during March in 2 - year - old
rams which had regressed testes . -
pubmed
Serum
CMV antibody titers have been measured over a period starting prior to transplantation as an approach to diagnosis of
cytomegalovirus ( CMV ) infection following renal transplantation . -
pubmed
A
myeloid cell line , designated
PL-21 , was established from the peripheral blood of a
patient with
acute promyelocytic leukemia . -
pubmed
Chromosome analysis of this cell line revealed a
human male
polyploid karyotype with 13q+ and double minute chromosomes . -
pubmed
From echocardiographic measurements , 39
patients with established , uncomplicated primary
hypertension (
diastolic pressure & gt ; 100 mmHg ) were classified as follows : normal - sized heart ( group 1 , 10 cases ) ; concentric
left ventricular hypertrophy ( group 2 , 18 cases ) ;
left ventricular hypertrophy and
cavity enlargement ( group 3 , 11 cases ) . -
pubmed
At variance with previous conclusions ( which were based on utilisation of electrocardiographic and chest x - ray criteria to define
hypertrophy ) it is suggested that left ventricular concentric
hypertrophy in
man consequent to sustained
hypertension is associated with an improved function . -
pubmed
Medical problems of geriatric
psychiatric patients and younger controls during electroconvulsive therapy . -
pubmed
Thirty - seven
arthritis patients participating in a drug withdrawal trial , simultaneously completed a 20 - point visual analogue scale and 7 - point verbal rating scale for
pain severity while on active medication and 48 hours following its withdrawal . -
pubmed
This is in good agreement with the value of 50 micrograms previously estimated for
honey bee stings and is the first reported data for the other species . -
pubmed
Nine
children with airway obstructing
hemangiomas were managed with
corticosteroid therapy for durations of 6 weeks to 17 months . -
pubmed
Therapy was continued for 8 months or longer in 6
patients , none of whom developed life - threatening
infections . -
pubmed
Steroid therapy is an effective method of protecting the airway in some
patients with
hemangiomas . -
pubmed
[ Evaluation of possible secondary prevention of
periodontal diseases in selected
patients ] . -
pubmed
Normal response to pregnancy in
rats cured of
streptozotocin diabetes by transplantation of one fetal pancreas . -
pubmed
The most frequent and severest
toxicity was
nausea and
vomiting seen in about the half of
patients being administered dosages ranged from 24 mg / m2 to 40 mg / m2 , and 3 out of 4
patients received dosages exceeding 50 mg / m2 required clinical managements ; moreover , 1 out of 2
patients administered 60 mg / m2 was ranked as grade 4 of the criterion of toxicities in WHO handbook . -
pubmed
Other clinical
toxicities such as
skin rash ,
hepatotoxicity or
nephrotoxicity observed in the minority of the
patients were reversible . -
pubmed
One
patient with
chronic myelogeneous leukemia had a hematological improvement and the other with
esophageal cancer had a partial response . -
pubmed
Hemolysis - induced
gallstones in
mice : increased unconjugated
bilirubin in hepatic bile predisposes to
gallstone formation . -
pubmed
We recently reported that nb / nb
mice with
hereditary hemolytic anemia spontaneously developed
calcium bilirubinate gallstones . -
pubmed
Recent studies hypothesized the involvement of
nitric oxide in
motility disorders of the
human gut . -
pubmed
Panniculectomy as an integral part of pelvic operation is an underutilized technique in
patients with morbid
obesity . -
pubmed
Fifteen
patients had significant medical problems and nine of the 16 had an
umbilical hernia . -
pubmed
All but one of the
wounds healed by first intention , and in that
patient , an 8 cm segment was easily resutured . -
pubmed
There was no increased
blood loss associated with the panniculectomy , but of note is the fact that the hematocrit level decreased in five
patients on days 2 to 5 postoperatively without
hematoma formation . -
pubmed
Congo red was bound from solution by
strains of
Porphyromonas gingivalis including W50 ,
HG189 ,
HG184 ,
NCTC 11834 , Bg 381 ,
WPH35 , the slower brown pigmenting colonial variant W50 / BR1 , and the avirulent mutant W50 / BE1 , and by
Porphyromonas endodontalis HG370 and
Porphyromonas asaccharolytica B537 . -
pubmed
These data , and our previous work , show that
Congo red and
iron protoporphyrin IX (
haemin ) are bound to different outer - membrane components , and that Congo red binding may be of little value as a marker to detect virulent
strains of
P. - pubmed
[ Primary treatment of unstable
pertrochanteric femoral fractures using a head - neck prosthesis in elderly
patients ] . -
pubmed
OBJECTIVE : Evaluation of the treatment of unstable
pertrochanteric femoral fractures with a femoral head prosthesis in older
patients . -
pubmed
METHOD : From January 1988 through December 1992 , 15
patients with 15 unstable
pertrochanteric femoral fractures were treated with a femoral head prosthesis and additional wiring of the trochanter . -
pubmed
A
patient who had undergone myocardial revascularization with a saphenous vein graft to the left anterior descending artery and a left internal thoracic ( mammary ) artery graft to the 1st diagonal branch presented with an unusual form of
subclavian steal syndrome . -
pubmed
We report a
patient with a slowly progressive
polyneuropathy associated with substantial slowing of conduction velocities initially suggestive of an acquired or
hereditary demyelinating polyneuropathy . -
pubmed
Sialadenitis associated with
periorbital disease in a
dog . -
pubmed
Submucosal
sialadenitis was diagnosed on histologic examination of a biopsy specimen from a
palatine swelling associated with acute , unilateral
periorbital disease in a
dog . -
pubmed
Intraoperative brachytherapy using I-125 pellets was reported to provide significant palliation and meaningful prolongation of life in highly selected
patients with unresectable
carcinoma of the pancreas . -
pubmed
Between December 1989 and December 1993 , 15
patients with biopsy - proven unresectable
adenocarcinoma of the pancreas were treated with interstitial
Pd-103 implants during laparotomy . -
pubmed
Pain relief was obtained within 3 - 6 weeks in 10 out of 12
patients presenting with
pain . -
pubmed
However , this study did not show any improvement in the median survival rate over I-125 due to the advanced stage
cancer in the majority of
patients in the study . -
pubmed
The performance of
broilers was examined under different days of placement ( after hatching ) and with three different types of waterers : 1 ) an automatic satellite waterer ; 2 ) a broiler Plasson waterer ; and 3 ) a regular Plasson waterer with a plastic ring in the trough of the waterer for 3 d. Male
broiler chicks ( 2,106 ) from a commercial
strain were randomly placed in 27 litter floor pens , with 9 pens per day of placement and waterer treatments . -
pubmed
There was a difference in
body weight ( P & lt ; .05 ) among the
broilers on the day of placement , with those on the day of hatch being heavier . -
pubmed
There was no difference in
body weights or feed conversion taken after the
broilers were on feed for 7 and 49 d after placement . -
pubmed
There was no difference in
body weight , feed conversion , or mortality within the three different waterer treatments except for the
broilers on the Plasson with the ring , which was higher in mortality percentage ( P & lt ; .05 ) than the broilers on the broiler Plasson waterer . -
pubmed
STUDY DESIGN : A prospective , randomized clinical trial of
patients with the diagnosis of postpartum
endometritis . -
pubmed
RESULTS : One hundred twenty - nine hospitalized
women with the diagnosis of
endometritis were enrolled . -
pubmed
OBJECTIVE : To assess the degree of variability of transient
myocardial ischaemia during daily life in
patients with
coronary artery disease , which could confound the interpretation of trials of the therapeutic effects of anti - ischaemic agents . -
pubmed
PATIENTS :
Patients with
stable angina , confirmed
coronary artery disease , and a positive treadmill exercise test for
ischaemia . -
pubmed
Patients were not preselected on the basis of prior documented transient
ischaemia during ambulatory ST segment monitoring . -
pubmed
RESULTS : There was marked variability in both ischaemic activity and mean duration of
ischaemia in
patients with confirmed
ischaemia , the greatest degree of variability being between
patients and from day to day within weeks within
patients , with a further contribution to variability being noted between fortnights within
patients . -
pubmed
The
strain patterns associated with normal activities were established for the
rat ulna from
strain gauges implanted in vivo . -
pubmed
These experiments show that the growing
rat ulna underwent adaptive changes in both bone mass and architecture when short daily periods of axial loading , producing
strains within the physiological range and with near normal
strain distribution , were superimposed on the loading associated with normal activity . -
pubmed
Ovariectomy - induced
bone loss can be affected by different intensities of treadmill running exercise in
rats . -
pubmed
These results suggest that bone in OVX
rats is either more sensitive to exercise than in sham - operated
rats or that the higher
body weight with slow running induces optimal loading and strengthens the bones . -
pubmed
In experiments to translate this into a role in pathogenicity , wild - type and mutant organisms were used in an intraperitoneal
mouse infection model . -
pubmed
Patients were divided into 325 subjects without cardiovascular risk factors and 895 subjects with cardiovascular risk factors ( 352 with
arterial hypertension alone , 298 with
arterial hypertension associated with other cardiovascular risk factors , 245 with
hypercholesterolemia ,
diabetes , cigarette smoking , alone or associated ) . -
pubmed
A preliminary anatomic - functional model , assembled from facts of
human paleoneuropsychiatry , more adequately contextualises
manic - depressive genomics and phenotypy . -
pubmed
Multiple genetic alterations , 4q28 , a new suppressor region , and potential gender differences in
human hepatocellular carcinoma . -
pubmed
The main purpose of this pilot study was to evaluate HFOV on adult
trauma patients with refractory
lung dysfunction . -
pubmed
In conclusion , all
patients improved after initiation of HFOV , and HFOV should be considered in the treatment of
patients with acute refractory
lung dysfunction . -
pubmed
Ionized
magnesium supplementation in
critically ill patients : comparing ionized and total
magnesium . -
pubmed
PURPOSE : The purpose of this study was to assess the effect of
magnesium supplementation on total
magnesium , ionized
magnesium , ionized
calcium ,
potassium , and pH in
critically ill cancer patients and to compare the validity of the measurements . -
pubmed
MATERIALS AND METHODS : Thirty - three consecutive
critically ill patients receiving
magnesium supplementation were placed in this prospective observational study at the Comprehensive Cancer Center , University Hospital . -
pubmed
The recombinants were scored by plating lysates on the amber - suppressor
Escherichia coli strain , on which an amberlike mutation was not expressed phenotypically . -
pubmed
Thirty - three
patients ( rheopheresis group , 17 ; control group , 16 ; mean age 64 + /- 10 years ) with acute
ischemic stroke were included in our prospective randomized trial . -
pubmed
CLINICAL CASE : We describe the case of a 69 year old female
patient with all the symptoms of
Wallenberg ' s syndrome and two potential causes of
stroke (
emboliogenic cardiopathy and
atherothrombotic vascular occlusion ) , in whom MR showed the presence of an isolated
bulbar lesion of unusual morphology which had previously been described as being of
thrombotic origin . -
pubmed
A case of a
degloving injury to the foot is presented in a
patient who also sustained severe contralateral lower - limb
trauma . -
pubmed
In
patients with
chronic hepatitis C ,
HCV RNA remained detectable in all
patients . -
pubmed
In conclusion , antiviral activity of rHuIL-12 in
patients with
chronic hepatitis B or C does not appear to be advantageous in comparison to other currently available treatments . -
pubmed
The median survival time for
patients with
TS & lt;or= 7.5 x 10(-3 ) ( 43 of 50
patients ) was 10.2 months , compared with 1.5 months for
patients with
TS greater than 7.5 x 10(-3 ) ( P & lt ; .001 ) . -
pubmed
Sulphasalazine - induced
systemic lupus erythematous in a
patient with
ankylosing spondylitis . -
pubmed
In
obese and particularly in morbidly obese
women suffering from skin friction ,
urinary stress incontinence ,
varicose veins , foot static problems and
pain , wearing insoles , suffering from
knee pain ,
low back pain or
hip arthritis were significantly more prevalent than in lean women ( P & lt ; 0.05 ) . -
pubmed
Between 1991 and 1995 , a total of 29
patients with
cancer of the hypopharynx were treated using laser surgical resection . -
pubmed
The highest local control rate was achieved in
patients with
carcinoma of the hypopharyngeal walls . -
pubmed
There were no functional deficits regarding speech and swallowing in 94 % , 100 % and 100 % of the surviving
patients without local
recurrence after 3 , 4 and 5 years , respectively . -
pubmed
Laser surgical treatment in combination with neck dissection and postoperative radiotherapy of selected
patients with early
cancer of the hypopharynx shows comparable results with open surgical procedures and is superior to radiotherapy alone . -
pubmed
Beclomethasone dipropionate (
BDP ) is a potent pro - drug to
beclomethasone (
BOH ) and is used in the treatment of chronic and acute
respiratory disorders in the
horse . -
pubmed
[ ELASTOTONOMETRIC AND GONIOSCOPIC EXAMINATION IN
PATIENTS WITH
DIABETES MELLITUS ] . -
pubmed
A SPECIAL CARE UNIT FOR
CHILDREN WITH SEVERE
DUAL MENTAL AND PHYSICAL HANDICAP . -
pubmed
Review of one hundred
hemiplegic patients . -
pubmed
The purpose of this study was to determine the frequency with which
patients report
paresthesia at the point that an acceptable motor response is obtained to low - intensity current electrical stimulation . -
pubmed
During nerve localization and while maintaining a motor response ( 0.20 mA-0.40 mA ) , the
patients were queried regarding any radiating sensation or
pain (
paresthesia ) in the shoulder or extremity on the side of the blockade . -
pubmed
None of the
patients spontaneously reported having a
paresthesia during nerve stimulation . -
pubmed
However , on careful questioning , half of the
patients ( 55 % ) reported electrical
paresthesia , defined as
dull tingling sensation traveling down to their hands and coinciding with the motor response . -
pubmed
In addition , most
patients ( 71 % ) spontaneously reported having a mild , radiating
paresthesia on initial injection of local anesthetic . -
pubmed
A 44 - year - old
man presented with a large and rapidly growing
skin lesion approximately six months after resection of a rectal
carcinoma . -
pubmed
The clinical outcome of
patients who have undergone liver transplantation for
hereditary hemochromatosis (
HH ) or who have received
iron - loaded donor grafts is unclear . -
pubmed
We reviewed 3,600 adult primary orthotopic liver transplants and assessed the outcomes in 22
patients with
HH . -
pubmed
HH patients had comparatively poor outcomes following transplantation : survival at 1 , 3 , and 5 years posttransplantation were 72 % , 62 % , and 55 % , respectively . -
pubmed
These recipients had appropriate early graft function , but 2
patients with heavy
iron loading and increased hepatic
iron developed hepatic
fibrosis . -
pubmed
This review evaluates the evidence that underlies the hypothesis that an energy deficit is instrumental in the
disturbance of bone turnover that has been observed in physically active
individuals . -
pubmed
Transthoracic tissue Doppler study of right ventricular regional function in a
patient with an
arrhythmogenic right ventricular cardiomyopathy . -
pubmed
Several new endovascular devices have been successfully tested for safety in
acute ischemic stroke patients and are now being tested for efficacy in larger clinical trials . -
pubmed
Chromosomal instability predicts
metastatic disease in
patients with
insulinomas . -
pubmed
Although the behavioral profiles typically associated with an increased risk for
STI ( including lifetime partner number , age at first intercourse , and so forth ) will certainly lead to an increased risk for
HPV detection , there is a high absolute prevalence of
HPV even among women who have few lifetime sex partners . -
pubmed
Many programmatic issues remain regarding the implementation of
HPV vaccine programs , including the marketing of the vaccine as
STI or
cancer prevention , as reviewed in detail by Gravitt and Shah [ 72 ] . -
pubmed
Therefore , although the public health success of
HPV vaccination is undoubtedly promising , the role of
cervical cancer screening as a secondary prevention effort should not be trivialized . -
pubmed
PURPOSE : Effective and tolerable palliative treatments are needed for
patients with incurable
squamous cell carcinoma of the head and neck (
SCCHN ) . -
pubmed
PATIENTS AND METHODS : Nineteen
patients with unresectable recurrent locoregional and/or distant metastatic
SCCHN with progressive disease after at least one prior chemotherapy or chemoradiotherapy regimen were enrolled onto this single - institution phase I study . -
pubmed
BACKGROUND :
Platanus acerifolia is an important cause of
pollinosis in Western European cities . -
pubmed
During saline , the vasodilator response to
acetylcholine was significantly blunted ( P=0.008 ) in
patients with
metabolic syndrome ( n=12 , 5 female ) compared with controls ( n=12 , 7 female ) , whereas the vasodilator response to
SNP was not different between groups ( P=0.68 ) . -
pubmed
However , many clinicians find management of
weight gain in
olanzapine treated
patients a challenge . -
pubmed
Phalangeal bone ultrasound is of limited value in
patients with
juvenile idiopathic arthritis . -
pubmed
OBJECTIVE : In
children with
juvenile idiopathic arthritis (
JIA ) , alterations of the skeletal system have been described . -
pubmed
The aim of this cross - sectional study was to evaluate a phalangeal bone ultrasound device in the assessment of the skeletal status in
children with active
JIA . -
pubmed
METHODS : In 49
children with oligoarticular , polyarticular or
systemic JIA , the speed of an ultrasound signal ( Ad - SOS ) through the phalanges of the dominant hand was measured using the Igea 1200 . -
pubmed
A
patient with
obstructive jaundice , a
tumour of the pancreatic head , CBD wall thickening , and pre - existing
PVT is presented . -
pubmed
OBJECTIVE : To test the effect of serial magnetic resonance ( MR ) coregistration on short - term brain volume changes using different semiautomated and automated brain volume techniques in
patients with relapsing - remitting ( RR )
multiple sclerosis (
MS ) . -
pubmed
However , the effect of coregistration on measurement of whole brain volume changes from serial scans in the short term has not been tested in
MS patients . -
pubmed
The neutralizing Ab responses as measured by peptide ELISA varied greatly between individual
pigs infected with each
PRRSV strain . -
pubmed
Urodynamic findings in female
patients with
urinary incontinence with intrinsic
sphincteric deficiency . -
pubmed
BACKGROUND : The aim of the study was to evaluate differences in urodynamic findings in
women with
urinary incontinence between subjects with or without
intrinsic sphincter deficiency (
ISD ) . -
pubmed
MATERIAL / METHODS : Sixty consecutive female
patients with a history and urodynamically confirmed diagnosis of pure
urinary incontinence were evaluated . -
pubmed
A new drug might make a positive contribution to existing therapies for
hypertension by : 1 ) reducing blood pressure ( BP ) via a novel pharmacologic mechanism ; 2 ) possessing pharmacologic or pharmacokinetic properties that make it superior to other members of its class ; or 3 ) facilitating BP control in refractory
patients . -
pubmed
Dendritic cells play a crucial role in initiating
tumour immunity as well as in the immune response for invading foreign pathogens such as
bacteria and viruses . -
pubmed
In this review , the functional roles of tumour - associated iDCs and the strategy for targeting iDCs in effective
tumour immunity for the
cancer patient are discussed . -
pubmed
Nasal obstruction in
children may also be a symptom of multiple benign nasal and
allergic disorders , making the initial diagnosis of
meningoencephalocele difficult . -
pubmed
RESULTS : Two
children , ages 15 months and 6 years , underwent successful endoscopic closure of their
anterior skull base defects and resection of their intranasal
meningoencephalocele with resolution of their
nasal obstruction and
cerebrospinal fluid rhinorrhea . -
pubmed
These results eliminate spontaneous mutation , between -
strain complementation , and heterotypic resistance as general explanations of multiply resistant
C. - pubmed
The aim of this study (
Alfacalcidol Alendronate Combined - AAC ) was to compare the efficacy and safety of a combined parallel therapy with
Alendronate and
Alfacalcidol to the treatment with either
Alendronate in combination with plain
vitamin D or
Alfacalcidol alone in
patients with established postmenopausal or male
osteoporosis . -
pubmed
We found 80 % of the
patients in the
Alendronate +
Alfacalcidol group free from
back pain at month 24 , compared to 30 % in the
Alendronate +
vitamin D and 43 % in the
Alfacalcidol monotherapy group . -
pubmed
INTRODUCTION :
Patients with moderate or severe
traumatic brain injury (
TBI ) may show impairment in decision- making processes . -
pubmed
OBJECTIVE : Investigate decision - making in
patients with moderate or severe
TBI during performance of the IGT , and study patient 's conscious knowledge of the task 's reinforcement contingencies ( reward / punishment schedule ) . -
pubmed
PATIENTS AND METHODS : Forty
patients with moderate or severe
TBI and 30 healthy
volunteers participated in the study . -
pubmed
IGT score differences were observed among
TBI patients in relation to level of knowledge of the task . -
pubmed
CONCLUSIONS : These results suggest that there is a direct relationship between the knowledge that
patients with moderate and serious
TBI have regarding the
TBI reinforcement contingencies and their performance in the task . -
pubmed
Stent implantation as a treatment option in
patients with thoracic
anastomotic leaks after esophagectomy . -
pubmed
BACKGROUND : In
patients with esophagectomy and gastric pull up for
esophageal carcinoma anastomotic leaks are a well - known complication and a major cause of morbidity and mortality . -
pubmed
OBJECTIVE : We evaluated stent implantation as a treatment option in
patients with thoracic
anastomotic leaks after esophagectomy . -
pubmed
METHODS : 269
patients with
esophageal cancer (
adenocarcinoma n = 212 ,
squamous cell carcinoma n = 57 ) had undergone esophagectomy and gastric pull up with an intrathoracic anastomosis between January 1998 and December 2005 . -
pubmed
A thoracic
anastomotic leak was clinically and endoscopically proven in 12
patients ( 4.5 % ) . -
pubmed
CONCLUSION : Stent implantation in
patients with thoracic
anastomotic leaks after esophagectomy is an easily available and effective treatment option with low morbidity , but stent migration does occur . -
pubmed
Based on increased exhaled
NO ( eNO ) levels in
patients with
asthma , eNO analysis has been proposed as a novel , noninvasive approach to the assessment and monitoring of
airway inflammation , and as a basis for adjustments in
asthma therapy . -
pubmed
INTRODUCTION : Positron emission tomography ( PET ) imaging with
copper ( II )- diacetyl - bis ( N4 - Methylthiosemicarbazone )( Cu - ATSM ) for delineating
hypoxia has provided valuable clinical information , but investigations in
animal models of
prostate cancer have shown some inconsistencies . -
pubmed
Helicobacter pylori is a chronic infectious agent defined as the major pathogen causing
gastritis ,
gastric and duodenal ulcer ,
gastric carcinoma and mucosa associated lenfoid tissue ( MALT )
lymphoma . -
pubmed
BACKGROUND :
Inguinal hernia in
children is traditionally repaired through a groin incision by dissecting the
hernia sac from the spermatic cord and suture ligating its base . -
pubmed
METHODS : Prospective review of 275
hernias in 187
children ( 144 male , 43 female ) performed laparoscopically by a single surgeon between September , 2002 and June , 2005 . -
pubmed
Four out of 275
hernias ( 1.5 % ) recurred in four
patients ( mean age 4.5 years ; 3 male , 1 female ) . -
pubmed
CONCLUSION : This novel laparoscopic
inguinal hernia repair is an effective method in
children , with
recurrence rates comparable to the traditional approach . -
pubmed
Klebsiella oxytoca bacteremia causing
septic shock in recipients of hematopoietic stem cell transplant : Two case reports . -
pubmed
Eight days following her autograft she developed
septic shock caused by
Klebsiella oxytoca bacteremia which was successfully treated with intravenous
meropenem and
gentamicin . -
pubmed
Seven months following her unsuccessful allograft , she developed
septic shock due to
Klebsiella oxytoca bacteremia caused by a
urinary tract infection . -
pubmed
To our knowledge , they are the first reports of
Klebsiella oxytoca bacteremias and
septic shocks in hematopoietic stem cell transplant recipients . -
pubmed
CONCLUSION :
Klebsiella oxytoca should be considered as a possible cause of severe
infections in recipients of various forms of hematopoietic stem cell transplantation . -
pubmed
The study groups were : Control- non
diabetic controls ( n=40 ) ( M : F 19:21 ) and
type 1 diabetic patients ( n=75 ) ( M : F 42:33 ) . -
pubmed
RESULTS :
Patients with
type 1 diabetes had significantly lesser joint mobility ( p & lt ; 0.0001 ) and higher plantar pressure ( p & lt ; 0.0001 ) compared with the control group . -
pubmed
CONCLUSION : In conclusion ,
type 1 diabetic patients in India had limited joint mobility which decreased further with longer duration of
diabetes and they had high plantar pressure also . -
pubmed
Newly discovered
ebola virus associated with
hemorrhagic fever outbreak in Uganda . -
pubmed
Over the past 30 years , Zaire and Sudan ebolaviruses have been responsible for
large hemorrhagic fever (
HF ) outbreaks with case fatalities ranging from 53 % to 90 % , while a third species ,
Cote d'Ivoire ebolavirus , caused a single non - fatal
HF case . -
pubmed
Due to the sequence divergence of this new virus relative to all previously recognized ebolaviruses , these findings have important implications for design of future diagnostic assays to monitor
Ebola HF disease in
humans and animals , and ongoing efforts to develop effective antivirals and vaccines . -
pubmed
Finally , conjugated
linoleic acid , which effectively lowers
body weight in
animals , has no such effect in
humans in the quantities provided by
dairy products . -
pubmed
AIMS AND OBJECTIVES : To evaluate the concurrent validity and reliability of the behavioural COMFORT and a modified version of the FLACC scale for assessment of
pain and sedation in intubated and ventilated
children and to evaluate the construct validity of the FLACC scale for assessment of
pain . -
pubmed
RELEVANCE TO CLINICAL PRACTICE : The use of validated scales may improve the assessment and management of
pain and sedation in intubated
children . -
pubmed
MATERIALS AND METHODS :
Wistar rats receiving total body irradiation of ( 60)Co gamma - rays alone or with combined radiation and skin
wound injury were used in this study . -
pubmed
RESULTS : Topical application of W(11)-a(12 ) into skin
wounds in
rats with combined 6 Gy total body irradiation and skin
wound injury could increase the neutrophils and macrophages in the wounded area and the nucleated cells in bone marrow at 24 h and 48 h , while the peripheral white blood cells did not show significant change . -
pubmed
We report a series of
patients undergoing radiofrequency catheter ablation of
ventricular arrhythmias (
VAs ) using RMN with either a 4 - mm catheter tip or an 8 - mm catheter tip at four different centers . -
pubmed
RESULTS : Twenty - eight
patients ( 43 % ) had
ischemic cardiomyopathy [
coronary artery disease (
CAD ) ] , 16
patients ( 25 % ) had non - ischemic
cardiomyopathy [
idiopathic dilated cardiomyopathy (
IDC ) ] , and 21
patients ( 32 % ) had structurally normal hearts ( SNH ) or
right ventricle outflow tract tachycardia (
RVOT ) . -
pubmed
In
patients with
structural heart disease (
CAD ,
IDC ) , success was achieved in 22 % with the 4 - mm catheter tip and in 59 % with the 8 - mm catheter tip ( p = 0.014 ) . -
pubmed
In
patients with
SNH / RVOT , success was achieved in 85 % with the 4 - mm catheter tip and in 87 % with the 8 - mm catheter tip ( p = 1.00 ) . -
pubmed
Such pits may be revealed by late complications such as orbital compressive
cyst of the optic nerve , even in previously normal adult
patients . -
pubmed
Key conclusions are ( 1 )
human research with intranasal
oxytocin has uniquely enhanced our understanding of the microstructure and function of the
human social brain , and ( 2 ) the
oxytocin system is a promising target for therapeutic interventions in a variety of conditions , especially those characterized by
anxiety and aberrations in social function . -
pubmed
Because only a few studies have focused on the
flavonoid structural requirements for neuroprotection , this work evaluated the protective capacity of 13
flavones structurally related to
quercetin , isolated from
Kenyan plants , to rescue primary cerebellar granule neurons from
death induced by a treatment with 24 h of
hydrogen peroxide ( 150 microM ) . -
pubmed
Multiple follicular cysts of the ear canal in a
dog . -
pubmed
This is the first report of multiple
follicular cysts originating from the ear canal in a
dog . -
pubmed
METHODS : We conducted a prospective observational study from March 2004 to September 2005 with consecutive
infants ( ages 1 - 12 months ) with severe acute
bronchiolitis and considered ready to be extubated . -
pubmed
Neither age greater than 35 years nor the presence of
hepatitis B virus core antibody was associated with INH -
hepatitis . -
pubmed
We find that birth -
death models of operon evolution reasonably describe the relative abundance of operons of different sizes in the
C. - pubmed
Central sleep apnoea syndrome is seen in approximately 40 % of
patients with
congestive heart failure . -
pubmed
Sleep apnoea is associated with an increased mortality in
patients with systolic
heart failure . -
pubmed
Because of its high prevalence , poor quality of life , poor outcome , and the beneficial effects of treatment , physicians treating
patients with
heart failure should be aware of central
sleep apnoea . -
pubmed
Lipoprotein subclasses determined by nuclear magnetic resonance spectroscopy and
coronary atherosclerosis in
patients with
rheumatoid arthritis . -
pubmed
OBJECTIVE :
Patients with
rheumatoid arthritis (
RA ) are at increased risk of
atherosclerosis , but routine lipid measurements differ little from those of people without
RA . -
pubmed
METHODS : We measured lipoprotein subclasses by NMR in 139
patients with
RA and 75 control subjects . -
pubmed
PURPOSE : To investigate the incidence , clinical features , pathogenic
bacteria , and risk factors associated with acute
prostatitis after transrectal prostate biopsy . -
pubmed
The incidence of acute
prostatitis after transrectal prostate biopsy was 2.0 % , and almost all cases were caused by
fluoroquinolone - resistant
E. - pubmed
Amidst a shortage of mental health professionals and against the backdrop of natural disasters , continued terrorism , and
pandemic influenza , there is a striking need to expand and operationalize available
human resources to enhance the psychological resiliency of those affected . -
pubmed
Secondary hyperaldosteronism in a
patient with
polyarteritis nodosa and
renal artery aneurysms . -
pubmed
PURPOSE : We wanted to evaluate the impact of
fentanyl matrix on the
pain and function of
patients with
spinal disorder - related chronic , non - malignant
pain . -
pubmed
OVERVIEW OF LITERATURE :
Patients with severe non - malignant
chronic low back pain may require opioid analgesics for effective
pain management . -
pubmed
METHODS : A total of 1,576
patients with severe
pain ( numeric rating scale = 7 ) were evaluated for their
pain intensity at the initial visit and at weeks 4 and 8 ( Visits 1 , 2 , and 3 , respectively ) . -
pubmed
Few studies have evaluated the effect of
cinacalcet on
anemia associated with SHPT in dialysis
patients , while no study has compared this
cinacalcet effect with that of
vitamin D analogs such as
paricalcitol . -
pubmed
[ Effect of
quercetin on neural stem cell proliferation in the subventricular zone of
rats after focal
cerebral ischemia -
reperfusion injury ] . -
pubmed
OBJECTIVE : To study the effect of
quercetin on the proliferation of neural stem cells in the subventricular zone ( SVZ ) of
rats after focal
cerebral ischemia . -
pubmed
METHODS : An adult
rat model of
middle cerebral artery occlusion (
MCAO ) model was established by placement of an intraluminal filament at the origin of the MCA . -
pubmed
Quercetin was administered intraperitoneally in the
rats at a dose of 50 mg / kg every 3 days starting at 6 h after MCAO , and
BrdU ( 50 mg / kg daily ) was also injected intraperitoneally starting at 4 h after
MCAO . -
pubmed
RESULTS : Compared with the sham - operated group , the
rats in the
ischemic model group showed significantly increased
BrdU - positive cells in the ipsilateral SVZ 7 days after
MCAO , reaching the peak level on day 14 and beginning to decrease on day 21 ( P<0.05 ) . -
pubmed
CONCLUSION :
Quercetin can maintain a high level of neural stem cell proliferation in the SVZ after focal
cerebral ischemia in adult
rats . -
pubmed
A new assay system for evaluation of developmental
immunotoxicity of chemical compounds using
respiratory syncytial virus infection to offspring
mice . -
pubmed
We evaluated the effect of
6 - propyl-2 - thiouracil (
PTU ) , an anti - thyroid agent , on developmental immunity using
respiratory syncytial virus ( RSV ) infection to offspring
mice as a new risk assessment for brominated flame retardants ( BFRs ) , because some BFRs are suspected of affecting the thyroid system . -
pubmed
Histopathological analysis revealed that
PTU - exposure exacerbated
pneumonia in
RSV - infected offspring . -
pubmed
Human behaviors determine health : strategic thoughts on the prevention of chronic non -
communicable diseases in China . -
pubmed
Prognosticators and risk grouping in
patients with lung
metastasis from
nasopharyngeal carcinoma : a more accurate and appropriate assessment of prognosis . -
pubmed
The purpose of this study was to identify the prognostic factors and to establish a risk grouping in
patients with lung
metastases from
NPC . -
pubmed
METHODS : A total of 198
patients who developed lung metastases from
NPC after primary therapy were retrospectively recruited from January 1982 to December 2000 . -
pubmed
CONCLUSIONS : In this study , clinical variables provided prognostic indicators of survival in
NPC patients with
lung metastases . -
pubmed
This prospective study evaluated the efficacy and safety of a new formulation ,
Tamsulosin OCAS ( Oral Controlled Absorption System ) , for
LUTS associated with BPH in Thai
patients . -
pubmed
MATERIALS AND METHODS : Fifty one
patients over 40 years old with complaints of
LUTS associated with
BPH were recruited . -
pubmed
At each visit ,
patients were assessed using the International Prostate Symptom Score ( IPSS ) ,
Nocturia Quality of Life ( N - QoL ) Questionnaire , QoL Assessment Index ( IPSS - QoL ) , and International Index of Erectile Function ( IIEF ) . -
pubmed
Three
patients experienced mild
dizziness . -
pubmed
CONCLUSION :
Tamsulosin OCAS treatment led to significant improvements in
LUTS ,
HUS and QoL in Thai
patients with
bladder outlet obstruction from
BPH with few side effects . -
pubmed
STUDY DESIGN : Histopathologic and immunohistochemical analysis of the herniated disc specimens obtained from 50
patients who had unilateral persistent
radicular pain or unilateral
radicular motor paresis . -
pubmed
It is well known that spontaneously
hypertensive rats ( SHR ) develop
muscle pathologies with
hypertension and
heart failure , though the mechanism remains poorly understood . -
pubmed
The
hepatitis C virus (
HCV ) causes one of the most prevalent chronic
infectious diseases in the world ,
hepatitis C , which ultimately develops into
liver cancer through
cirrhosis . -
pubmed
CONCLUSION : A significant health disparity exists in the prescribing pattern of
epinephrine autoinjectors for
peanut -
allergic children from families of differing SES . -
pubmed
Body composition in lean
women with
polycystic ovary syndrome : effect of
ethinyl estradiol and
drospirenone combination . -
pubmed
BACKGROUND : Limited data are available regarding the potential effects of
oral contraceptives (
OCs ) on body fat distribution particularly in lean
women with
polycystic ovary syndrome (
PCOS ) . -
pubmed
STUDY DESIGN : Participants included 28 lean
patients with
PCOS and 28 age- and
body mass index ( BMI)-matched healthy
women . -
pubmed
The
PCOS patients received
ethinyl estradiol 30 mcg /
drospirenone 3 mg for 6 months . -
pubmed
OC therapy for 6 months in
PCOS patients results in an increased total and trunk fat percentage despite no change in clinical anthropometric measures including weight , BMI and WHR . -
pubmed
Prodrug of
green tea epigallocatechin-3 - gallate (
Pro - EGCG ) as a potent anti - angiogenesis agent for
endometriosis in
mice . -
pubmed
Green tea epigallocatechin-3 - gallate (
EGCG ) can inhibit angiogenesis and development of an experimental
endometriosis model in
mice , but it suffers from poor bioavailability . -
pubmed
In this study , the potential of
pro - EGCG as a potent anti - angiogenesis agent for
endometriosis in
mice was investigated . -
pubmed
In conclusion , pro -
EGCG significantly inhibited the development , growth and angiogenesis of experimental
endometriosis in
mice with high efficacy , bioavailability , anti - oxidation and anti - angiogenesis capacities . -
pubmed
The objective of the present study was to compare the demographics , risk factors , and clinical outcomes between patients with
biliary tract infection caused by ESBL - producing and non - producing
Klebsiella pneumoniae and
Escherichia coli . -
pubmed
METHODS : Between February 2005 and August 2010 , we collected 159 cases with
biliary tract infection caused by
K. - pubmed
CONCLUSION : ESBL status of bacterial isolates for patients with
biliary tract infection caused by
K. - pubmed
BACKGROUND : Hydration and anticoagulation are the standard of care for
cerebral venous sinus thrombosis (
CVST ) but some
patients remain refractory to medical management and warrant more aggressive therapy . -
pubmed
OBJECTIVE : Present an alternative technique for endovascular transvenous thrombectomy in a series of
CVST patients . -
pubmed
METHODS : We reviewed the records of six
patients with medically refractory
CVST . -
pubmed
On imaging , four of the six
patients had
hemorrhage ,
edema , and mass effect present before treatment , while two had
edema only . -
pubmed
OBJECTIVE : : To evaluate if 20 is a possible critical PJK angle in primary adult
scoliosis surgery
patients as a threshold for worse
patient - reported outcomes . -
pubmed
METHODS : : Clinical and radiographic data of 90 consecutive primary surgical
patients at a single institution ( 2002 - 2007 ) with adult
idiopathic / degenerative scoliosis and 2 - year minimum follow - up were analyzed . -
pubmed
The patient was a 59 - year - old postmenopausal
woman with multiple
liver metastases at first examination . -
pubmed
The continuation of
trastuzumab is considered effective after having progressed by
trastuzumab including pretreatment , and we consider it worth while to give a combination of
trastuzumab and
capecitabine to
patients with extensive
liver metastases and associated
impaired liver function , because of the treatment 's synergistic effect and low risk of causing severe adverse events . -
pubmed
Patients had neither
cold intolerance nor
scar hypersensitivity . -
pubmed
ES-62 , an immunomodulator secreted by filarial nematodes , exhibits therapeutic potential in
mouse models of
allergic inflammation , at least in part by inducing the desensitisation of Fc epsilon RI - mediated mast cell responses . -
pubmed
In two of the three
patients with ruptured
aneurysms , consciousness level on admission was
stupor . -
pubmed
The main source of
infections is beef or greens contaminated with
E. - pubmed
Patients with
osteogenesis imperfecta , known
vitamin D deficiency , and skeletal or
metabolic dysplasia were not included in the study . -
pubmed
RESULTS : Sixteen
infants ( age range 1 - 11 months , seven
males and nine
females ) with 23
rib fractures were analysed . -
pubmed
In pediatric
patients biliary atresia and different forms of
metabolic liver disorders represent the main indication for liver transplantation . -
pubmed
Effects of a 12 - week aerobic training on glycemic control in
type 2 diabetes mellitus male
patients . -
pubmed
Atypical features in a
patient with
acute promyelocytic leukaemia : a potential diagnostic pitfall . -
pubmed
In
patients with
acute leukaemia , a high index of suspicion is required to exclude
APML . -
pubmed
Several species of tick - borne rickettsiae that were considered nonpathogenic for decades are now associated with
human infections , and novel Rickettsia species of undetermined pathogenicity continue to be detected in or isolated from ticks around the world . -
pubmed
Approaches to study
yeast cell aging and
death . -
pubmed
For c. 50 years ,
yeast has been an established model organism for basic and applied research , and more specifically , for c. 15 years , this unicellular organism has been applied to dissect molecular mechanisms of cell aging and programmed cell
death . -
pubmed
The study determined the effect of chronic
ethanol use on the therapeutic window of
d4 T ,
3TC and
NVP in
HIV - infected patients using
alcohol - use biomarkers to screen
patients for chronic
ethanol use . -
pubmed
Grading slightly failed to be significantly inversely associated , and survival analysis revealed no significant survival benefit of
CD166 - positive patients . -
pubmed
Primary resuscitation , debridement , urgent reduction of
dislocation , and adequate antibiotic support resulted in good clinical outcome in our
patient . -
pubmed
CASE PRESENTATION : We describe a case of isolated
right ventricular endomyocardial fibrosis in a 27 - year - old Caucasian
man from a temperate climate who presented initially with frank
hemoptysis and
pulmonary thromboembolic disease . -
pubmed
CONCLUSIONS : We conclude that
endomyocardial fibrosis should be included in the differential diagnosis of
apical cardiomyopathies in
patients from temperate climates . -
pubmed
We retrospectively reviewed the clinical and radiographic results of THA performed in 167 hips for 100
patients with
AS . -
pubmed
In
patients with
AS with severe
pain , limited motion and posture , as well as
deformity , the overall outcomes after THA were found to be favorable with an encouraging midterm prosthetic survivorship , a low complication rate and a high level of patients ' satisfaction . -
pubmed
Identification of
human papillomavirus status specific biomarker in
head and neck cancer . -
pubmed
BACKGROUND : In an attempt to improve the prognosis of
patients with
head and neck cancer , it could be necessary to identify biomarkers in homogeneous subgroups of
patients with
head and neck cancer . -
pubmed
METHODS : We explored the necessity of
human papillomavirus ( HPV ) status - specific biomarkers in patients with
head and neck cancer and identified an
HPV status - specific gene set . -
pubmed
RESULTS : The identified gene set for distinguishing
head and neck cancer from head and neck normal , did not accurately discriminate the
HPV specific patients with
head and neck cancer from the head and neck normal group . -
pubmed
It is expected that
HPV status - specific biomarkers can be helpful in deciding therapeutic methods for patients with
head and neck cancer , after biological validation and large prospective trials . -
pubmed
Vasopressin Associated With an Increase in Return of Spontaneous Circulation in
Acidotic Cardiopulmonary Arrest Patients . -
pubmed
OBJECTIVE : Determine if
vasopressin therapy in combination with
epinephrine was associated with improved outcomes in
patients with
cardiac arrest compared to
epinephrine alone . -
pubmed
Patients & gt;=18 years of age with documented
cardiac arrest requiring ACLS and vasopressor therapy were included . -
pubmed
Subgroup analysis of ROSC in
patients with an arterial pH of & lt;7.2 ( n = 35 ) showed an increased rate of
ROSC ( 63 % vs 37 % , P = 0.01 ) in the
vasopressin plus
epinephrine group versus the
epinephrine alone group , respectively . -
pubmed
CONCLUSIONS :
Vasopressin in combination with
epinephrine demonstrated improved ROSC in
cardiac arrest patients with initial arterial pH & lt;7.2 compared with
epinephrine alone , without improving survival to hospital discharge . -
pubmed
To confirm the anti -
influenza activity of these
flavonoids , we used an in vivo
mouse model . -
pubmed
In
mice infected with
human influenza , oral administration of
3,4 DHF significantly decreased virus titers and pathological changes in the lung and reduced body
weight loss and
death . -
pubmed
BACKGROUND : The European Carotid Surgery Trial ( ECST ) risk model is a validated tool for predicting cerebrovascular risk in
patients with symptomatic
carotid disease . -
pubmed
Patients were followed up until carotid endarterectomy , recurrent cerebral event ,
death , or study end . -
pubmed
We recently mapped a major
OS susceptibility QTL to
mouse chromosome 14 by comparing alpha - radiation induced
osteosarcoma in
mouse strains which differ in their
tumor susceptibility . -
pubmed
Inflammation has a key role in the pathogenesis of various
human diseases . -
pubmed
Whereas most deletion
strains had no detectable difference in growth compared to wild - type
yeast , two - thirds of deletion
strains had alterations in metabolic profiles . -
pubmed
METHOD : A group of 210 adult middle - class Mexican non - diabetic obese
patients was evaluated : 105 normal weight
individuals , and 105
non - diabetic obese . -
pubmed
Microscopic images are acquired from blood and bone marrow smears of
patients with
Acute lymphoblastic leukemia and normal cases . -
pubmed
Phthalates are a group of synthetic compounds mainly used as plasticizers , which have been classified as endocrine - disrupting chemicals and potential
human -
cancer causing agents . -
pubmed
Systolic murmur in a young
man who had previous
ventricular septal defect repair : the double - chambered right ventricle . -
pubmed
MATERIALS AND METHODS : The ultrasound appearances of ten histologically proven
subcutaneous IPEH in ten
patients ( age range , 15 - 69 years ; mean age , 38.2 years ; six
females , four
males ) were reviewed retrospectively by two musculoskeletal radiologists . -
pubmed
Risk of
lower extremity arterial disease in a cohort of
workers occupationally exposed to ionizing radiation over a prolonged period . -
pubmed
In this study the incidence risk of
lower extremity arterial disease ( LEAD ; international classification of diseases version 9 code 440.2 ) was assessed in a cohort of
workers occupationally exposed to radiation over a prolonged period . -
pubmed
CONCLUSION : Our PEGylated liposome formulation reported in this study could potentially produce viable clinical strategies for improved delivery of
DOC for the treatment of
human cancer . -
pubmed
Translational Pharmacokinetic - Pharmacodynamic Modeling and Simulation : Optimizing
5 - Fluorouracil Dosing in
Children With Pediatric
Ependymoma . -
pubmed
To select a
5 - FU dosage for our clinical trial in
children with
ependymoma , we simulated various
5 - FU dosages for
tumor exposures and
tumor growth inhibition , as well as considering tolerability to bolus 5 - FU administration . -
pubmed
We developed a pediatric population PK model of bolus 5 - FU and simulated
tumor exposures for our
patients . -
pubmed
Simulations for
tumor concentrations indicated that all
patients would be above the 1 - hour target exposure for antitumor effect . -
pubmed
In this study , we compared the in vitro
cytotoxicity of
CuO NPs of two distinct sizes ( 4 and 24 nm ) using the
A549 human lung cell line . -
pubmed
We report on a 68 - year old
patient who developed
necrotizing fasciitis of the right elbow with
multiorgan failure and long - term ventilation after an accidental and minor
injury . -
pubmed
Local
recurrence was observed in 9
patients and distant
metastases in 15
patients . -
pubmed
Tumors that were & gt;=3 cm in maximal dimension were associated with a worse overall survival and
patients with neoadjuvant radiation were at increased risk of complications . -
pubmed
Type 2 diabetes was induced in
rats by high
fructose - high fat diet and low
streptozotocin dose . -
pubmed
In addition ,
4 - AB administration improved the elevated blood pressure and the associated exaggerated vascular contractility , endothelial destruction and
vascular inflammation seen in
diabetic animals . -
pubmed
We found that
Mo POM nanoparticles , especially complex 3 , inhibited the growth of
human hepatocellular liver carcinoma cells (
HepG2 ) through cellular reactive
oxygen species levels ' elevation and mitochondrial membrane potential damage . -
pubmed
Finally , as proof of concept , the method was applied to
human kidney tissue where a clear differentiation between
kidney cancer and nontumorous material could be demonstrated on the basis of unsupervised statistical analysis . -
pubmed
Valproate Reduces Delayed
Brain Injury in a
Rat Model of
Subarachnoid Hemorrhage . -
pubmed
We tested whether SD - inhibitor
valproate reduces
brain injury in an
SAH rat model with and without experimental
SD induction . -
pubmed
CONCLUSIONS : In our
rat SAH model ,
valproate treatment significantly reduced
brain lesion growth after
KCl application . -
pubmed
In the present case study , a 27 - year - old
woman with a large
myxoma originating from the left ventricular free wall is studied . -
pubmed
Several of the same agents alter metabolic function in
human cells and are associated with
human obesity or
metabolic dysfunction in
humans . -
pubmed
We address the evidence for a role in the genesis of
obesity for viral agents in five broad categories : adenoviridae , herpesviridae , phages ,
transmissible spongiform encephalopathies ( slow virus ) , and other
encephalitides and
hepatitides . -
pubmed
This approach will serve as the basis for the development of oral
plant - based vaccines against
PD with several potential advantages such as low cost , easy scale - up during production , and easy administration . -
pubmed
Rechallenge to
Carboplatin in
Children with Low Grade
Glioma and
Carboplatin Hypersensitivity Reactions . -
pubmed
Background :
Carboplatin based regimens have demonstrated activity in pediatric
patients with
low grade gliomas (
LGG ) . -
pubmed
Methods : We performed a retrospective review of
children with
LGG treated between January 1994 and July 2015 with
carboplatin and
vincristine who had a documented
CHR . -
pubmed
Hypersensitivity reactions occurred in 6
patients ( 20.7 % ) of the first , and 10
patients ( 55.5 % ) of the second group , respectively . -
pubmed
Pasteurella multocida meningoencephalitis in an immunocompetent adult with multiple cat scratches . -
pubmed
P multocida is a Gram - negative coccobacillus which frequently colonises the nasopharynx of animals ; it is a recognised but very rare cause of
meningoencephalitis in immunocompetent adults . -
pubmed
Digitally Barcoding
Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of
Tuberculosis . -
pubmed
To better understand the lesional biology of
TB infection , we digitally barcoded
M. - pubmed
Hydrogen peroxide and
nitric oxide regulation of phenolic metabolism under
water stress and
ABA in
wheat . -
pubmed
[ Effects of seawater immersion on the inflammatory response and
oxygen free radical
injury of
rats with superficial partial - thickness scald at early stage ] . -
pubmed
Objective : To study the effects of seawater immersion on the inflammatory response and
oxygen free radical
injury of
rats with superficial - thickness scald at early stage . -
pubmed
Conclusions : Seawater immersion can enhance the inflammatory response and
oxygen free radical
injury of wounds and the whole body of
rats with superficial partial - thickness scald at early stage . -
pubmed
Human emotions , such as
anxiety ,
depression , fear , joy , and laughter , profoundly affect psychological and physiological processes . -
pubmed
We aimed to determine the impact of soy on cardiometabolic health ,
adipose tissue inflammation , and the cecal microbiota in ovariectomized ( OVX )
rats bred for low - running capacity ( LCR ) , a model that has been previously shown to mimic
human menopause compared to sham - operated ( SHM ) intact control LCR
rats . -
pubmed
Furthermore , soy significantly improved blood lipid profile ,
adipose tissue inflammation , and aortic stiffness of LCR
rats . -
pubmed
Cabazitaxel in the treatment of
metastatic castration - resistant prostate cancer :
patient selection and special considerations . -
pubmed
Clinicians must familiarize themselves with the most recent studies as well as
drug toxicities to determine the best treatment option for their
patients . -
pubmed
MATERIAL AND METHODS : Pregnant
women ( n=74 ; 30 [ 23 - 38 ] years ) were consecutively recruited from the district of Warsaw , Poland , and divided into healthy subjects ( HS , n=45 ) , and women with a diagnosis of
AITD (
AITD , n=29 ) . -
pubmed
Forty drug - naive
patients with
mild cognitive impairment or mild
dementia with evidence of
amyloid deposition are 1:1 randomized to receive either the multinutrient combination or placebo once daily . -
pubmed
METHODS : The medical records of consecutive
patients with basic horizontal
strabismus who underwent a rectus muscle plication or resection combined with a known amount of antagonist
muscle recession from January 2009 - June 2016 by one surgeon were reviewed retrospectively . -
pubmed
RESULTS : A total of 162
patients with basic
esotropia ( 88 lateral rectus muscle plications ; 74 lateral rectus resections ) and 60
patients with basic
exotropia ( 31 medial rectus muscle plications ; 29 medial rectus resections ) were included . -
pubmed
No significant differences were found when analyzing the change in ocular alignment between the plication and resection groups for
patients with either basic
esotropia or basic
exotropia . -
pubmed
METHODS : Consecutive
patients with
LSTs 3 cm or larger were enrolled for from May 2010 - 2016 . -
pubmed
CONCLUSIONS : ESD appears to be an effective and safe method for
LSTs larger than 3 cm in older
patients . -
pubmed
Mice bearing established
subcutaneous tumors were studied . -
pubmed
In contrast ,
VV.CXCL11 increased the number of total and antigen - specific T cells within
tumors after CAR T cell injection or vaccination and significantly enhanced anti -
tumor efficacy . -
pubmed
METHODS : Vaginal pH was determined using standard pH paper strips in two clinical trials involving postmenopausal
women with
signs and symptoms of
VVA evaluated before and after intervention with vaginal
estradiol in softgel capsules . -
pubmed
The primary
tumor site was colorectal in 76 , kidney in 14 , head and neck in 13 , breast in 12 , stomach in 8 , urinary tract in 7 , and other organs in 12
patients . -
pubmed
RESULTS : 11,553
trauma patients were admitted , 596
patients ( 5.2 % ) died . -
pubmed
These results suggest that measuring the
Trp /
Kyn ratio may be useful for evaluating immunological status during endocrine therapy in elderly
patients with locally advanced
breast cancer . -
pubmed
The obtained results showed that the
cytotoxicity differed according to the used extract with an efficient effect of
Cotula cinerea extracts compared to
Salvia verbenaca . -
pubmed
A potent
cytotoxicity was thus observed for the
Cotula cinerea hexane extract which inhibited the growth of
RD cell line at the lowest IC50 value ( 57.21 + -3.43 microg / mL ) . -
pubmed
The results of this study showed thus that
Cotula cinerea essential oil and
hexane extract showed significant
cytotoxic effects against
RD and
Vero cell lines , respectively , and could be considered as novel source of antitumor agents . -
pubmed
This study is expected to be beneficial for clinical and traditional applications for
Cotula cinerea as a remedy against
cancer and opens new perspectives for further investigations on other types of
cancer cell lines . -
pubmed
The reconstruction of neo - tongue with vastus lateralis myofascial free flap may be represent a valid surgery for
patients with
cancer tongue . -
pubmed
STUDY SAMPLE : 417 consecutive
patients seeking treatment for
tinnitus in an Audiology Department in the UK . -
pubmed
This case highlights the importance of the utility of bedside ultrasound in
patients presenting to the ED with
flank pain or
abdominal pain which can lead to expedited assessment and appropriate management . -
pubmed
As chemo - radiotherapy continues to increase the lifespan of
patients with
nasopharyngeal carcinoma (
NPC ) , adverse reaction and drug resistance remain two major problems when using
cisplatin (
CDDP ) . -
pubmed
Annually , the prevalence of
low back pain in the general US adult population is 10 - 30 % , and the lifetime prevalence of US
adults is as high as 65 - 80 % . -
pubmed
Survival outcomes for
patients with
glioblastoma (
GBM ) are universally poor with only a small percentage of
patients surviving five years beyond initial diagnosis . -
pubmed
Following
tumor resection , the
patient underwent concomitant radiation and
temozolomide therapy that was complicated by
CMV colitis and
abdominal abscesses . -
pubmed
Despite not receiving adjuvant
temozolomide , the
patient demonstrated a five year progression - free survival before requiring re - resection for radiation
necrosis . -
pubmed
We report an unusual case of loss of psychic self - activation appeared immediately after a
cardiac arrest in a middle age
patient . -
pubmed
Two years later , although the cognitive performances of our
patient were improved , a second brain MRI demonstrated bilateral
pallidal lesions , suggesting a possible mechanism with delayed
hypoxic lesions . -
pubmed
Phylogeography of
Potamon ibericum ( Brachyura : Potamidae ) identifies Quaternary
glacial refugia within the Caucasus biodiversity hot
spot . -
pubmed
We studied phylogeography of
Potamon ibericum ( Brachyura : Potamidae ) in the drainages of the western Caucasus biodiversity hot
spot ( i.e. -
pubmed
In our study , we aimed to compare the effects of perioperative peritonsillar
dexamethasone -
bupivacaine and
bupivacaine - alone infiltration on
pain control in pediatric
patients . -
pubmed
Patients with
pain score & gt;= 4 were treated with
paracetamol rescue analgesia . -
pubmed
A 38 - year - old
man presented with an acute onset of
pain and
swelling of the right testis . -
pubmed
The dose- and time - dependent
glomerulopathy with progression to chronic progressive
nephropathy in female
rats appears to be a direct effect of
avagacestat and was not ameliorated with co - administration of
17beta - estradiol or an antihypertensive (
enalapril ) and was not present in control OVX
rats . -
pubmed
In this study , we identified a cardiac endothelial - enriched lncRNA - lnc000908 , which was markedly up - regulated in
rats with
cardiac fibrosis . -
pubmed
We hypothesize that polymorphisms in the same gene may increase a
patient 's risk of developing
hepatotoxicity when receiving potentially
hepatotoxic agents during chemotherapy . -
pubmed
Establishment and characterization of a new
patient - derived
anaplastic thyroid cancer cell line (
C3948 ) , obtained through fine - needle aspiration cytology . -
pubmed
Here we describe the establishment and characterization of a new
patient - derived cell line , obtained from an unresectable
ATC through fine - needle aspiration cytology ( FNAC ) . -
pubmed
Metabolic and Inflammatory Effects of an
omega-3 Fatty Acid - Based Eucaloric Ketogenic Diet in
Mice With
Endotoxemia . -
pubmed
BACKGROUND : Dietary strategies can aid in the management of
critically ill patients . -
pubmed
We aimed to determine the effects of a eucaloric ketogenic diet ( EKD ) enriched with
omega-3 fatty acids ( O3KD ) on
glucose levels and
inflammation in
mice with
endotoxemia . -
pubmed
CONCLUSION : An O3KD leads to reduced
inflammation and maintains
glucose homeostasis in
mice with
endotoxemia . -
pubmed
Salivary FRAP as A Marker of
Chronic Kidney Disease Progression in
Children . -
pubmed
The study included 30
children with
CKD and a control group matched by age and gender . -
pubmed
We demonstrated that total FRAP , FRAP - UA and UA were significantly higher in stimulated saliva , as well as urine of
CKD patients compared to the controls . -
pubmed
Interestingly , salivary FRAP and
uric acid clearly differentiate between various stages of
CKD as well as between healthy and ill
children . -
pubmed
Although salivary FRAP may be a potential
CKD biomarker in
children , further studies are needed in a larger group of
patients . -
pubmed
Primary visual cortical thickness in correlation with
visual field defects in
patients with
pituitary macroadenomas : a structural 7 - Tesla retinotopic analysis . -
pubmed
Growing evidence suggests secondary damage to remote visual structures may contribute to
vision loss in
patients with chiasmatic compression . -
pubmed
METHODS : Eight
patients ( 4
males and 4
females , mean age 44.3 years ) with
pituitary adenomas who exhibited chiasmatic compression and
visual field defects , as well as 8 matched healthy controls ( 4
males and 4 females , mean age 43.3 years ) , were scanned at 7 - T MRI for this prospective study . -
pubmed
Patients with
adenoma additionally underwent neuroophthalmological examination including 24 - 2 Humphrey automated visual field perimetry . -
pubmed
These results further characterize changes in the posterior visual pathway associated with chiasmatic compression , and may prove useful in the neuroophthalmological workup for
patients with
pituitary macroadenoma . -
pubmed
METHODS : We performed a retrospective study from 2 institutions of
patients with
intracranial aneurysms who underwent treatment with WEB device alone or in conjunction with stenting and/or coiling in an off - labeled location . -
pubmed
RESULTS : Eleven
patients with 12
aneurysms were included . -
pubmed
Effects of soft tissue surgery on transverse kinematics in
patients with
cerebral palsy . -
pubmed
BACKGROUND :
Gait disturbances , including flexed knee gait ,
stiff knee gait , and
tip - toeing gait , are common in
patients with
cerebral palsy (
CP ) . -
pubmed
CONCLUSIONS : This study found that the transverse kinematics were improved to a more external angle after soft tissue surgery in
patients with
CP . -
pubmed
Therefore , clinicians should consider that soft tissue surgery can affect the transverse plane kinematics in
patients with
CP . -
pubmed
To confirm our findings , further research regarding the natural history of
femoral and tibial torsion in
children with
CP is needed . -
pubmed
Background :
Xerostomia occurs in the majority of
patients undergoing chemoradiation therapy for
head and neck cancer (
HNC ) . -
pubmed
Materials and Methods : This single - center randomized study was conducted in 30
patients treated with radiotherapy with or without chemotherapy for HNC between 2014 and 2017 , who had at least grade 1 or 2 symptomatic
dry mouth (
xerostomia ) according to CTEP NCI Common Terminology Criteria for Adverse Events ( CTCAE version 4.0 ) . -
pubmed
A 19 - Year - Old
Man With Vaping - Associated
Lung Injury . -
pubmed
Clinical guidelines from the United States and Europe do not recommend treatment with
statins for primary prevention in
patients with
hypercholesterolemia who are older than 75 years . -
pubmed
Silver - coated zero - valent
iron nanoparticles enhance
cancer therapy in
mice through lysosome - dependent dual programed cell
death pathways : triggering simultaneous apoptosis and autophagy only in cancerous cells . -
pubmed
In the xenograft
mouse model ,
cancer growth was significantly inhibited by a single dose of systematically administered NPs without significant
weight loss in animals . -
pubmed
Among the double co -
infections , those of
E. - pubmed
Coenzyme Q10 supplementation of
human oocyte in vitro maturation reduces postmeiotic
aneuploidies . -
pubmed
OBJECTIVE : To evaluate the effect of
coenzyme Q10 (
CoQ10 ) supplementation on oocyte maturation rates and postmeiotic
aneuploidy rates during in vitro maturation ( IVM ) of
human oocytes . -
pubmed
RESULT(S ): In
women aged 38 - 46 years , 50 mumol / L
CoQ10 significantly increased oocyte maturation rates ( 82.6 % vs. 63.0 % ; P=.035 ) , reduced oocyte
aneuploidy rates ( 36.8 % vs. 65.5 % ; P=.020 ) , and reduced chromosome
aneuploidy frequencies ( 4.1 % vs. 7.0 % ; P=.012 . -
pubmed
Enhancing of
anthracnose disease resistance indicates a potential role of antimicrobial peptide genes in
cassava . -
pubmed
Cassava anthracnose disease , caused by
Colletotrichum gloeosporioides f.sp . - pubmed
To minimize the effects of such disease , this study investigated the response of
cassava to attack by
CAD and how the plants defend themselves against this threat . -
pubmed
Differential expression profiles of six candidate genes were observed in response to
CAD infection of both
cassava cultivars . -
pubmed
The
patient is a 22 - year - old
female with a history of a
posterior fossa medulloblastoma diagnosed 8 years prior for which she underwent surgical resection followed by adjuvant chemotherapy and craniospinal radiation . -
pubmed
Functional network connectivity ( FC ) and long - term potentiation ( LTP ) , considered as the plasticity substrate of learning and memory , were longitudinally assessed in
mice of the P301S model of
tauopathy following the course ( time and location ) of progressively neurodegenerative pathology ( i.e. -
pubmed
Oxidized
Zirconium Total Knee Arthroplasty Implant Failure in a
Patient With
Knee Instability . -
pubmed
We report a case of an oxidized
zirconium total knee arthroplasty failure in a
patient with
knee instability . -
pubmed
Though
honokiol , derived from the
Magnolia tree , was known to suppress
renal fibrosis ,
pulmonary fibrosis ,
non - alcoholic steatoheptitis ,
inflammation and
cancers , the underlying antifibrotic mechanisms of
honokiol are not fully understood in hepatic stellate cells until now . -
pubmed
In this study , we sought to build a machine learning model for predicting LVR in
AMI patients after effective percutaneous coronary intervention ( PCI ) that contains the majority of the clinical risk factors and compare 3D STE parameters values for LVR prediction . -
pubmed
We enrolled 135 first - onset
AMI patients ( 120
males , mean age 54 + - 9 years ) . -
pubmed
This study compared the NLR , PLR , and MLR values in the
manic and euthymic phases of the same
patients . -
pubmed
METHODS :
Patients who met the inclusion criteria and were hospitalized due to
bipolar affective disorder manic episodes at the Ondokuz Mayis University Faculty of Medicine inpatient psychiatry clinic between 01.01.2013 and 01.01.2019 were enrolled in the study . -
pubmed
One hundred thirteen
patients undergoing
manic episodes were included . -
pubmed
Complications rate of and risk factors for the unplanned reoperation of degenerative
lumbar spondylolisthesis in elderly
patients : a retrospective single - Centre cohort study of 33
patients . -
pubmed
English full - text studies that included
human subjects experiencing a
cutaneous reaction comprising
granulomatous inflammation as the direct result of a drug were included . -
pubmed
Adult
mammalian cardiomyocytes ( CM ) are postmitotic , differentiated cells that can not re - enter the cell cycle after any appreciable
injury . -
pubmed
CASE REPORT : A 49 - year - old
woman presented to our Emergency Department ( ED ) with a complaint of
epigastric pain radiating to the left shoulder . -
pubmed
Peripheral - nerve lipid abnormalities in
patients on
perhexiline maleate . -
pubmed
Putrescine and
spermidine in the
cyst coat of the protozoan
Colpoda steinii [ proceedings ] . -
pubmed
Recovery from monocular stimulus deprivation
amblyopia in the
kitten . -
pubmed
A review of experimental studies on recovery from monocular stimulus deprivation
amblyopia in the
kitten is presented . -
pubmed
The conclusions drawn from these experimental studies of monocular deprivation suggest a possible approach to the treatment of
human amblyopia . -
pubmed
Although situated in a holoendemic region with constant
human movements in and out of the town , the mining company has succeeded in controlling
malaria in Yekepa . -
pubmed
The dominant
malaria parasite in the area was
Plasmodium falciparum . -
pubmed
At each
tolbutamide dose level the mean IRI response of
obese subjects was about three times greater than in controls . -
pubmed
In
acromegalic subjects an increased response was observed only after the 200 mg dose of
tolbutamide . -
pubmed
There were seven
patients during pregnancy and eight after delivery who required hospitalization and treatment for
congestive heart failure . -
pubmed
Five of the
patients were not given anticoagulation therapy , but when
thromboembolism developed ,
warfarin was administered . -
pubmed
In the first two groups , four
patients had episodes of
thromboembolism . -
pubmed
Man and many other
animals have mobilizing mechanisms for preparation for physical activity , expressed inter alia by an increase in blood pressure ,
hyperglycaemia and
hyperlipidaemia . -
pubmed
The clinical significance of the disturbance in
magnesium metabolism is discussed on results of two groups of
patients with
hyperthyroidism . -
pubmed
One group of 7
patients with high serum
thyroxine levels and mild clinical signs of
thyrotoxicosis showed a normal
magnesium concentration in serum . -
pubmed
A
patient with a newly recognised variant of
biotinidase deficiency presented with acute bilateral
visual loss at the age of 10 years . -
pubmed
The
patient no longer has
back pains , and no signs of
bone metastases were seen on both scintigrams for two years and eight months from December 1988 to August 1991 . -
pubmed
It is expected that the successfully treated
patients even with bone
metastasis will be increasingly reported from now as various new approaches including induced
hypertension chemotherapy are introduced . -
pubmed
In 19
patients with closed - loop
intestinal obstruction , including 16
patients with strangulating obstruction , the findings at examination with computed tomography ( CT ) were retrospectively correlated with the surgical and pathologic findings and evaluated by two radiologists . -
pubmed
Fever was a presenting sign in 8 of 11
patients , whereas all 4 patients who presented with
back pain had
nontuberculous lumbar osteomyelitis or
disk space infections . -
pubmed
Elderly
patients ,
diabetics , and patients with
chronic disease are susceptible to this kind of occult
infection and may present with minimal clinical findings . -
pubmed
Verapamil prevents slowing of transmural conduction and suppresses
arrhythmias in an isolated
guinea pig ventricular model of
ischemia and reperfusion . -
pubmed
This procedure has been applied to
patients with
keratoconus ,
myopia , and
aphakia . -
pubmed
Several large studies of epikeratoplasty have been conducted which suggest that the procedure be limited to
keratoconus and
aphakic patients who are contact and spectacle lens intolerant . -
pubmed
One or more adverse sequelae were present in 11 ( 22 % )
obese and in 9 ( 18 % ) of non - obese
women , proportions not significantly different . -
pubmed
Plasma
zinc levels were measured in 14
patients with primary
affective disorder on admission to hospital ; they were compared with plasma
zinc levels in group of 14 age- and sex - matched controls . -
pubmed
Plasma
zinc levels of 9 of the
depressed patients on admission to hospital and at the point of discharge were compared ; a significant increase in
zinc levels was detected . -
pubmed
In the other two
patients with
SVC syndrome , a trans - sternal surgical approach was applied in order to resect a large
tumor extending into the anterior mediastinum . -
pubmed
Combination chemotherapy for
patients with advanced
carcinoma of the cervix : trial of
mitomycin - C ,
vincristine ,
bleomycin , and
cisplatin . -
pubmed
Sixteen
patients with metastatic or recurrent
carcinoma of the cervix were treated with combination chemotherapy consisting of
mitomycin - C ,
vincristine ,
bleomycin , and
cisplatin . -
pubmed
Ultrastructure of capillary walls in
human brain tumors . -
pubmed
Changes in capillary walls between
human glial , non - glial and metastatic
brain tumors were studied with conventional ultrathin section and freeze - fracture replica techniques . -
pubmed
To further define the clinicopathologic features and determinants of survival , we reviewed the cases of 110
patients with primary
hepatic malignancy managed surgically between 1975 and 1986 . -
pubmed
Intermittent
shock titration task in the
rhesus monkey and its validity as an analgesiometric procedure . -
pubmed
The case for treating
women at high risk of
breast cancer with the anti - oestrogen
tamoxifen is presented . -
pubmed
Thymic lymphomas appeared with a short latent period of 4 - 5 weeks in BALB / c
mice and 8 weeks in C57BL/6
mice . -
pubmed
Authors present two cases of
thyroid carcinoma in female
patients ages 6 and 7 years with a two month evolution before diagnosis . -
pubmed
The ESR before the exchange arthroplasty averaged 53 mm / h. ESR values at 6 weeks , 3 and 6 months after the exchange operation were lower in 60
patients in whom the
infection healed than in 16
patients whose
infection had not healed . -
pubmed
Establishment of six
human pancreatic cancer cell lines and their sensitivities to anti -
tumor drugs . -
pubmed
Six
human pancreatic cancer cell lines
PK-1 , - 8 , -9 , -12 , -14 and -16 , were established . -
pubmed
They originated from either primary
pancreatic cancer biopsy or liver
metastasis biopsy , or xenografts of these biopsy specimens in athymic
nude mice . -
pubmed
Active defence of retinal temperature during
hypothermia of the eye in
cats . -
pubmed
Sixty - one
women with a past history of
elevated blood pressure ( high - risk group ) associated with
oral contraceptive use ( 27
patients ) , unknown etiology ( 17
patients ) , or
preeclampsia ( 17
patients ) used a low - dose
oral contraceptive containing 0.4 mg of
norethindrone and 35 micrograms of
ethinyl estradiol for 3 to 24 months . -
pubmed
Sixty - one
women without a past history of
elevated blood pressure ( low - risk group ) , selected from a pool of 616 low - risk
patients , were matched with the high - risk group for race , initial age , initial
body weight , duration of use , history of smoking , and family history of
hypertension . -
pubmed
Five high - risk
patients ( 8.2 % ) discontinued therapy because of the redevelopment of
hypertension ; however , blood pressures at discontinuance were comparable to the previous
highest blood pressures . -
pubmed
Distribution of pneumococcus - induced augmentation of tissue
leukostasis in
rabbits : specificity for the pulmonary vascular bed . -
pubmed
We studied whether
pneumococcal ( PNC ) sonicate - induced
leukostasis is specific for the lung or whether it occurs in extrapulmonary foci as well . -
pubmed
[ LINAC radiation effect on
human glioma and glial cells ] . -
pubmed
Ultrastructure of the "
cyst - like bodies " of
Trypanosoma conorhini . -
pubmed
[ Therapy with
gentamicin in
patients operated for
heart diseases . -
pubmed
Deletion ,
monosomy , and multiple
monosomy -
trisomy mosaicism in
chicken embryos . -
pubmed
[ Frequency of double pre - beta bands during electrophoresis on membrane foil of lipids from
patients with
vascular diseases ] . -
pubmed
Clinical diagnoses included
cellulitis ( 39
patients ) ,
abscesses ( 14 ) , infected
ulcers ( 3 ) , and
bursitis ( 1 ) . -
pubmed
Effect of exercise training on the blood pressure and hemodynamic features of
hypertensive adolescents . -
pubmed
When the
subjects were retested 9 + /- 1 months after cessation of training , systolic BP and VO2 max had returned to pretraining levels ; however ,
diastolic BP was still below pretraining levels in the subjects who had diastolic
hypertension initially . -
pubmed
These data indicate that moderate endurance exercise training can lower BP in otherwise healthy
hypertensive adolescents as an initial therapeutic intervention . -
pubmed
Clinical experiences with
oxyfedrine in
patients with
angina pectoris . -
pubmed
This adoptive transfer was studied in an inbred
strain of
syrian hamsters . -
pubmed
The influence of aorto - coronary bypass surgery ( ACBS ) on
ventricular arrhythmia was examined in 57
patients . -
pubmed
Complex
PVCs were present in 8
patients preoperatively and in 9
patients after ACBS . -
pubmed
To determine whether or not changes in renal gluconeogenesis in vivo were accompanied by altered renal handling of
phosphate , possibly related to
NAD + action on BBM
phosphate transport in vivo , renal gluconeogenesis was stimulated in
rats by
metabolic acidosis . -
pubmed
Chronic
acidosis in
rats previously adapted to low
phosphorus diet was associated with increased UPiV ( controls , 68 + /- 19 ;
acidotic , 1055 + /- 428 nmoles / mg
creatinine ; P less than 0.05 ) without changes in plasma
phosphate and
creatinine (
Cr ) and in UCrV compared to controls . -
pubmed
Decreased BBM transport of
phosphate in proximal tubules of
acidotic rats may explain the increased UPiV. -
pubmed
[
Gastric stasis induced by stress in the
rat : its reversal by
clebopride ] . -
pubmed
Hepatobiliary functional scintigraphy ( HBFS ) using
99 m Tc - labeled Diethyl - IDA was tested in 84
patients suffering from various
hepatic and bile duct disorders . -
pubmed
Ninety - nine
hypertensive patients who had been on antihypertensive therapies for at least six months because of
diastolic blood pressure of 105 mg Hg or more were interviewed immediately after seeing their physicians . -
pubmed
The carriage on
skin lesions , on healthy skin and in the nose , of micro - organisms that produce antibiotics active against
Staphylococcus aureus has been studied . -
pubmed
No evidence could be found that the presence of producer organisms in
skin lesions had a protective effect against colonisation by
S. - pubmed
A correlation with the toxicity observed in other
species is developed by establishing the effect of a prototype compound for each
toxicity and tests of one or more compounds expected to lack such
toxicity . -
pubmed
Open label trial with
vigabatrin in
children with intractable
epilepsy . -
pubmed
Thirty
children ( 20
males , 10
females ) with intractable
epilepsy received
vigabatrin (
VGB ) as an open label basis to preexisting antiepileptic drugs . -
pubmed
The result of treatment was categorized as ' responders ' with 13 ( 43 % ) having 50 - 75 % reduction of
seizure frequency ; and ' non - responders ' which consisted of 17
children . -
pubmed
[ Suture material and suturing of the laparotomy
wound in
horses and
cattle ] . -
pubmed
To study the prevalence of
insulin resistance in
patients with
polycystic ovary syndrome (
PCO ) and the correlation between
hyperinsulinemia and
hyperandrogenism , 48
patients were divided into four groups : group 1 , non - obese ovulatory
women ( n = 10 ) ; group 2 ,
obese ovulatory
women ( n = 9 ) ; group 3 , non - obese
women with
PCO ( n = 14 ) ; group 4 ,
obese women with
PCO ( n = 15 ) . -
pubmed
There was also a high prevalence of
insulin resistance in
patients with PCO regardless of
obesity , and
hyperandrogenism - aggravated
insulin resistance . -
pubmed
By conducting electrophysiological tests on
patients with facial nerve
paralysis , the characteristics of
synkinesis and the mechanisms of its manifestations were examined . -
pubmed
The subjects were 114
patients of facial nerve
paralysis on whom electroneurography ( ENoG ) and the blink reflex were conducted . -
pubmed
The authors describe a case of symptomatic cranial settling in a nonrheumatoid
patient with chronic , severe ,
spasmodic torticollis resulting in erosive changes in the occipito - atlanto - axial complex . -
pubmed
RESULTS : There was a significant difference not only between
tumor sizes of 2 cm or larger and those of less than 2 cm ( p & lt ; 0.001 ) , but also between
patients with lymph node metastasis and
patients free from it ( p & lt ; 0.001 ) . -
pubmed
Because , in vitro , PMNs from
patients with
UC appear normal and are not therefore a likely cause for the enhancements , we hypothesized an abnormal colonic milieu . -
pubmed
Using rectal dialysis , we sampled the colonic milieu in
patients with active
UC , in
patients with inactive
UC , and in control subjects . -
pubmed
Blood monocytes from healthy donors and
breast cancer patients as well as tissue macrophages from
patients with fibrocystic changes of the breast were also examined . -
pubmed
BACKGROUND :
Flutamide withdrawal has been reported to benefit
patients with
hormone - refractory prostate cancer . -
pubmed
METHODS : Sixteen
patients with
hormone - refractory prostate cancer were enrolled in the study . -
pubmed
The time to
cancer progression for these 8
patients was 2 to 15 months ( mean , 4 months ) . -
pubmed
To test this ,
normal melanocyte lines (
melan - a and
C57 M ) of C57BL/6
mice were infected with the
MelARV produced by
B16BL6 melanoma . -
pubmed
Two infected melanocyte sublines showed morphological changes , were able to grow in the absence of
TPA and , after inoculation into
C57BL / 6 mice , produced rapidly growing , highly
pigmented tumors . -
pubmed
Thus , our data imply that the ecotropic MelARV that somatically emerged in
B16 and other
melanomas of C57BL/6
mice may play a role in malignant transformation . -
pubmed
Thirteen
asthmatic patients ( 29 + /- 15 years , 4
men and 9
women ) were randomly assigned to receive one nebulization of each of the three treatment regimens at 24 h interval . -
pubmed
PATIENTS AND METHODS :
Patients with inoperable or metastatic
colorectal cancer were randomized to receive monthly
FU 400 mg / m2 / day plus
LV 20 mg / m2 / day as intravenous push daily for five days , or FU alone . -
pubmed
RESULTS : Clinical trials of
UFT published in the Western world have included 581
patients with
colorectal cancer . -
pubmed
These diseases include
Crohn disease ,
ischemic colitis , intestinal
Behcet disease , Enterohemorrhagic
E. - pubmed
coli including
O157 , antibiotics associated
hemorrhagic colitis and so on . -
pubmed
Possible immunologic interaction between
infection with
human T lymphotropic virus type 1 (
HTLV-1 ) , a retrovirus , and the intestinal parasite
Strongyloides stercoralis was investigated in persons infected with one or both agents . -
pubmed
BACKGROUND : Population - based data are unavailable concerning the predictive value of
orthostatic hypotension on mortality in ambulatory elderly
patients , particularly minority groups . -
pubmed
Adenoid cystic carcinoma of the lacrimal gland simulating a
dermoid cyst in a 9 - year - old
boy . -
pubmed
Adenoid cystic carcinoma of the lacrimal gland is a
malignant neoplasm that is generally found in
adults and is usually managed by orbital exenteration and supplemental external beam irradiation or chemotherapy . -
pubmed
A recent report has suggested that the
tumor may have a less malignant course in
children . -
pubmed
We describe a case of
adenoid cystic carcinoma of the lacrimal gland that simulated a
dermoid cyst clinically and radiographically in a 9 - year - old
boy . -
pubmed
Although no prognostic conclusions can be drawn on the basis of a single case report with short follow - up , the relatively earlier detection of this
tumor made possible by modern orbital imaging studies may allow total removal at an earlier stage and prevent orbital exenteration in a
patient with normal vision . -
pubmed
Pneumocystis carinii remains an important cause of
pneumonia in immunocompromised patients , particularly in those who have
acquired immune deficiency syndrome . -
pubmed
Oncogenes ,
tumor - suppressor genes , and cell - survival genes have all been found to be dysregulated in some
myeloma patients . -
pubmed
Pamidronate , a second - generation
bisphosponate , has been shown to be effective at decreasing adverse skeletal events in
patients with advanced
myeloma . -
pubmed
Through such
injuries , workers risk
infection ( the average
infection risk from
injuries is 1 in 300 ) with deadly diseases such as Hepatitis B or C , or
HIV , the virus that causes
AIDS . -
pubmed
Similarities between ileal
Crohn ' s disease and
indomethacin experimental jejunal
ulcers in the
rat . -
pubmed
BACKGROUND : Both
Crohn ' s disease ileal
ulcers and
indomethacin - induced jejunal
ulcers in the
rat have a predilection for the mesenteric margin of the bowel wall . -
pubmed
METHODS : Ileal
Crohn ' s disease ulcers identified in surgical resection specimens ( n=5 ) and
indomethacin - induced lesions in the
rat jejunum ( n=6 ) were examined macroscopically and histologically . -
pubmed
RESULTS : In both the
human ileum and the
rat jejunum ,
ulcers occurred consistently along the mesenteric margin , with the most extensive
mucosal injury occurring at two adjacent sites on either side of the midline of this margin . -
pubmed
CONCLUSIONS : For anatomical reasons apparently related to the vasculature of the
human and
rodent small bowel , specific sites along the mesenteric margin are susceptible to
Crohn ' s disease ulceration and NSAID damage , respectively . -
pubmed
Renal handling of
zinc in
insulin - dependent diabetes mellitus patients . -
pubmed
Hyperzincuria is a common feature in diabetic
patients , which is still not understood . -
pubmed
Based on the above consideration , the aim of the present study was to investigate the renal handling of
zinc in
insulin - dependent diabetes mellitus (
IDDM )
patients . -
pubmed
About 10 % of all
patients develop secondary
MDS /
leukemia . -
pubmed
This seems to be one important step in leukemogenesis in
CN patients . -
pubmed
METHOD : A
patient suffering from
Wolff - Parkinson - White syndrome was investigated prior the catheter ablation . -
pubmed
bulgaricus 2038 ,
yogurt starters , were chosen as test -
strains , and
ether extracts of these cultures were used as samples . -
pubmed
112
patients ( 17
men , 95
women , mean age 46.5 + /- 3.8 ) with various
thyroid diseases were examined . -
pubmed
Benign diseases were revealed in 96 ( 85.7 % )
patients ,
thyroid cancer -- in 16 ( 14.3 % ) . -
pubmed
,
Pantoea agglomerans ,
Citrobacter freundii and
Serratia marcescens strains isolated from children between 0 and 3 years of age is presented . -
pubmed
METHODS : Bilateral 3 - wall intrabony
periodontal defects were surgically induced in the premolar region in the maxilla and mandible in 8 young adult Korean mongrel
dogs . -
pubmed
Bone marrow cytogenetic complete remission achieved by
interferon - alpha plus
cytarabine ocfosfate therapy in a
patient with
chronic myelogenous leukemia during extramedullary
blast crisis . -
pubmed
We report herein the case of a 67 - year - old
man who was admitted to our hospital with a 3 - month history of
hoarseness , a
cervical mass , and weak muscles of the extremities 6 years after undergoing a right colectomy for
carcinoma . -
pubmed
The
patient eventually died from the
malignancy , although he survived for 4 months after the disclosure of the
metastases . -
pubmed
All
patients received a
low molecular weight heparin as a prophylaxis for
deep venous thrombosis . -
pubmed
Patients operated on the day of admission had more
bleeding complications than those who were operated on the day after admission ( 19/145 ( 13 % ) compared with 4/61 ( 7 % ) ) . -
pubmed
Smoking and use of antihypertensive medication were registered more often in
patients without
bleeding complications . -
pubmed
Eleven
patients with
NCAH due to
11 - beta OH deficiency and 15 control
subjects were involved in the study . -
pubmed
The main complaint of the
patients with
NCAH was
hirsutism and the diagnosis was made if the adrenal
11 - deoxycortisol response to
SDT exceed threefold the 95th percentile of controls . -
pubmed
Peak
11 - deoxycortisol responses to
LDT were significantly ( p & lt ; 0.05 ) higher in
NCAH patients ( 15.7 + /- 1.8 nmol / L ) than in the control subjects ( 6.5 + /- 0.8 nmol / L ) . -
pubmed
Incidence of
juvenile osteodystrophy in hand - reared grey parrots (
Psittacus e erithacus ) . -
pubmed
Amiodarone induced
corneal deposits are the most common reversible side effects ( 70 - 100 % ) in
humans . -
pubmed
During follow - up for 1 - 122 months ( mean 27,3+/-1,5 months ) signs of
keratopathy were found in 280
patients ( 93,9 % ) . -
pubmed
The fact that coliform - free
rabbits tolerate exposure to a degree and duration of
hemorrhagic shock which is lethal for
rabbits that possess the normal flora , and that these tolerant
rabbits lose their tolerance when
E. - pubmed
That there is a proportionality between the size of the pool of endotoxin and the tolerance of
hemorrhagic shock is suggested by the survival rate of several series of coliform - free
rabbits fed
E. - pubmed
BACKGROUND : Epidemiological studies have linked the consumption of chlorinated surface waters to an increased risk of two major causes of
human mortality ,
colorectal and bladder cancer . -
pubmed
CDC Earl ' , predominated over H97 - 2 , isolated from the susceptible
cv . ' Harrington ' , from the first to the last of four
infection cycles on both ' CDC Earl ' and ' Harrington ' . -
pubmed
PATIENTS AND METHODS : All 8
patients suffered from progressive
loss of vision caused by exudation into the macular area . -
pubmed
RESULTS : All
patients showed complete regression of the
tumor . -
pubmed
No
patient showed any sign of
recurrence during the follow - up of up to 60 months . -
pubmed
CONCLUSION : The long - term results of
patients with active
choroidal hemangioma demonstrate that PDT is a most effective and safe treatment option . -
pubmed
We are reporting a case of an immunocompromised
patient with invasive
aspergillosis (
IA ) who developed aspergillotic
granulomas and a
mycotic aneurysm of the superior cerebellar artery . -
pubmed
At the same time , chronic UVR induced the marked
epidermal hyperplasia in
human and
mouse skin . -
pubmed
The in vivo antitumor activity of 3G3 was tested in
human glioblastoma (
U118 ) and
leiomyosarcoma (
SKLMS-1 ) xenograft
tumor models in athymic
nude mice . -
pubmed
It is concluded that investigations on experimental
toxicity , dietary intake , and potential
human health effects of
PCDEs are clearly necessary . -
pubmed
PCI in ST - elevation
infarction -- one flew over the
cuckoo 's nest . -
pubmed
We describe a case of
left ventricular neurofibroma in a 56 - year - old
woman with
Von Recklinghausen disease . -
pubmed
Endoscopic surgery for spontaneous
basal ganglia hemorrhage : comparing endoscopic surgery , stereotactic aspiration , and craniotomy in noncomatose
patients . -
pubmed
METHODS : Ninety noncomatose
patients with
basal ganglia hemorrhages were randomized into 3 groups . -
pubmed
Postoperatively ,
patients were evaluated by magnetic resonance imaging ( MRI ) , with contrast , for volume and rostral - caudal extent of
scar tissue and nerve root involvement . -
pubmed
Back and leg
pain and quality of life were assessed by neurologic examinations and standardized
patient surveys . -
pubmed
Neurologic examinations and
patient surveys showed substantial reductions in
pain over time in both groups but no significant differences between groups . -
pubmed
Concomitant use of
atomoxetine and
OROS -
methylphenidate in a 10 - year - old
child suffering from
attention - deficit / hyperactivity disorder with comorbid
bipolar disorder and
Tourette syndrome . -
pubmed
Atomoxetine and
OROS methylphenidate were successfully used concomitantly in a 10 - year - old
boy suffering from
attention - deficit / hyperactivity disorder (
ADHD ) with comorbid
bipolar disorder and
Tourette syndrome (
TS ) . -
pubmed
EXEGESIS : We report the case of a 69 - year - old
woman treated by corticotherapy for an
aortitis thought to be inflammatory , who required emergency surgery when a dissected
aneurysm appeared . -
pubmed
BACKGROUND : Oxidative stress is prevalent in dialysis
patients and has been implicated in the pathogenesis of
cardiovascular disease and
anaemia . -
pubmed
An 84 - year - old
patient with an
atrial septal defect rescued using the Amplatzer septal occluder device . -
pubmed
We report the case of a rescued 84 - year - old
patient with
atrial septal defect (
ASD ) who was emergently admitted to our intensive care unit with progressive
dyspnea requiring mechanical ventilation for severe
anoxia and
respiratory arrest . -
pubmed
Obesity is considered a mild inflammatory condition and predisposes
individuals to an increased risk of developing many diseases . -
pubmed
The results reported by Croci and Zarini in this issue highlight the anti - inflammatory and anti -
hyperalgesic effect of
rimonabant in
obese animals , so suggesting that it could provide a more general and aggressive strategy to protect
obese patients from many pathological risks . -
pubmed
BACKGROUND :
Malignant gliomas are the most common primary
brain tumours of both
children and
adults . -
pubmed
Significant attention has been given , recently , to immunotherapy which , although promising in preclinical studies , has not yet enhanced the survival of
patients with
glioblastomas . -
pubmed
In the study we present treatment , dealing with operative difficulties and rehabilitation in a 52 - year - old
patient with an inveterate
fracture of the Barton type of the distal radius with
dislocation in the radiocarpal joint . -
pubmed
Asthma is a common condition that can substantially affect
patients ' quality of life . -
pubmed
However , we report a case of paradoxical
bronchoconstriction in a 36 - year - old
man who was recently diagnosed as having new - onset
asthma and was treated with
levalbuterol . -
pubmed
These findings support the study of the use of the combination of
bortezomib and
CGC-11093 in
MM patients that fail to respond to frontline therapy . -
pubmed
Prosthesis type has minimal impact on survival after valve surgery in
patients with moderate to
end - stage renal failure . -
pubmed
BACKGROUND : Few previous studies have reported on the outcome of
patients with
renal failure (
RF ) undergoing valvular surgery , particularly with regard to choice of valve prosthesis . -
pubmed
METHODS : We retrospectively analyzed prospectively collected data from 155
patients with
RF ( mean age 62 + /- 14 , 42 % female ) who underwent left - sided valve surgery from January 1998 to December 2006 . -
pubmed
Patients were divided into two groups : Group 1 ( non - dialysis - dependent
renal failure (
NDRF ) ;
creatinine & gt;2.5 mg / dl ; n = 47 , 40 % ) and Group 2 (
renal failure dialysis ( DRF ) ; n = 108 , 60 % ) . -
pubmed
Moreover , OXM ameliorates
hyperglycemia and significantly reduces apoptosis in
murine beta - cells after
streptozotocin administration and directly reduces apoptosis in
thapsigargin - treated INS-1 cells . -
pubmed
Results indicate that acute
MDMA , at dose of 3 mg / kg , notably
impaired copulatory behavior of sexually experienced male
rats . -
pubmed
Fusarium culmorum causes
ear blight disease on cereal crops resulting in considerable losses to grain yield , quality and safety . -
pubmed
In this study , the
Arabidopsis floral infection model was used to assess the impact of five defence mutants on disease . -
pubmed
PATIENT(S ):
Women were divided into two groups :
leiomyoma ( n = 120 ) and
nonleiomyoma ( n = 112 ) . -
pubmed
DESIGN :
Patients ( n = 203 ) with a diagnosis of
gastroesophageal cancer underwent nutritional assessment (
body mass index , anthropometric measures ,
dysphagia scoring , and estimation of dietary intake ) . -
pubmed
Excretory - secretory products of
Toxocara canis larvae have been considered as a major functional antigen in immune responses against
toxocariasis . -
pubmed
Children born small for gestational age or with very low
birth weight : clinical similarities and potential benefits of growth hormone therapy . -
pubmed
In particular , two research areas need special focus in short VLBW
children : the effects of growth hormone treatment ( which shows dose - dependent efficacy on postnatal growth in short SGA
children ) , and
insulin sensitivity ( which seems altered , as in short
SGA children ) . -
pubmed
The importance of valve sparing
tumour resection even in asymptomatic
patients is emphasised . -
pubmed
We examined oxidative stress markers of 31
patients suffering from
ALS , 24
patients suffering from
PD and 30 healthy subjects were included . -
pubmed
A trend for an enhancement of
oxidized glutathione was noted in
ALS patients . -
pubmed
BACKGROUND : Neuroimaging and electrophysiologic studies have consistently provided evidence of impairment in anterior cingulate cortex / medial frontal cortex function in
people with
schizophrenia . -
pubmed
RESULTS : In
schizophrenia subjects , we found decreased blood
oxygen level - dependent signal in the medial frontal wall , with significant clusters restricted to more dorsal regions compared with healthy subjects . -
pubmed
In addition , we observed a trend - level decrease in
N - acetylaspartate /
creatine (
NAA /
Cr ) levels and a significant positive correlation between
NAA /
Cr level and the blood
oxygen level - dependent signal in
schizophrenia subjects that did not exist in healthy subjects . -
pubmed
[ Reduced cardiopulmonary exercise capacity in
patients with chronic
heart failure : impact of
left ventricular systolic dysfunction ] . -
pubmed
OBJECTIVE : To evaluate the cardiopulmonary exercise capacity in
patients with chronic
heart failure (
CHF ) . -
pubmed
There were 37
patients with LVEF & lt ; 0.45 in
CHF group and another 37
patients with LVEF & gt ; 0.50 in control group . -
pubmed
CONCLUSION : ( 1 ) Cardiopulmonary exercise capacity is reduced in
CHF patients . -
pubmed
Benefits of dental implants installed during ablative
tumour surgery in
oral cancer patients : a prospective 5 - year clinical trial . -
pubmed
OBJECTIVE : This prospective study assessed treatment outcome and
patient satisfaction of
oral cancer patients with a mandibular overdenture on implants up to 5 years after treatment . -
pubmed
MATERIALS AND METHODS : At baseline , 50 consecutive edentulous
oral cancer patients , in whom prosthetic problems were expected after oncological treatment , were evaluated by standardized questionnaires and clinical assessments . -
pubmed
RESULTS : At the 5 - year evaluation , 26
patients had passed away and four
patients had to be excluded from the analyses , because superstructures were not present , due to persistent local irritation ( n=2 ) , loss of three implants ( n=1 ) and the impossibility of making an overdenture related to
tumour and oncological surgery - driven anatomical limitations ( n=1 ) . -
pubmed
CONCLUSIONS : It was concluded that
oral cancer patients can benefit from implants installed during ablative surgery , with a high survival rate of the implants , a high percentage of rehabilitated
patients and a high denture satisfaction up to 5 years after treatment . -
pubmed
BACKGROUND :
Patients with single left ventricle ( LV ) physiology maybe at increased risk for
myocardial dysfunction and mechanical dyssynchrony . -
pubmed
Modified Yu index for
strain and strain rate time to peak was longer in the single LV
patients vs. controls ( 51.2 + 18.2 ms vs. 27.9 + 8.0 ms and 90.2 + 24.2 ms vs. 52.5 + 23.7 ms , respectively ) . -
pubmed
Moreover , plasma levels of adipokines have been investigated in
patients with
nonalcoholic fatty liver disease in order to establish correlations with the underlying state of
insulin resistance and with the type and severity of
hepatic damage . -
pubmed
In
humans , decreased PPI has been reported to be associated with
anxiety . -
pubmed
Percutaneous versus surgical revascularization in
patients with
ischemic mitral regurgitation . -
pubmed
BACKGROUND : The proper way of revascularization remains controversial in
patients with
ischemic mitral regurgitation (
IMR ) . -
pubmed
BACKGROUND : Aerosol delivery of surfactant and
perfluorocarbon ( PFC ) is a desirable therapeutic approach for the treatment of various
lung diseases in
patients undergoing mechanical ventilation . -
pubmed
Renal disease affects approximately 30 % of
patients with
JBTS , presenting itself in most cases as
nephronophthisis (
NPHP ) , a
structural tubulo - interstitial disorder characterized by thickened basal membrane of the tubular epithelium and progressive
interstitial fibrosis , associated with
cysts at the cortico - medullary junction . -
pubmed
We propose three cases concerning three
patients with
JBTS having different years of illness and degrees of
renal impairment , evaluating the parameters of renal function at the time of genetic diagnosis and seen after a follow - up of 7 years . -
pubmed
The aim of this study was to investigate the difference between the pharmacokinetics of
haloperidol in normal
rats and in
rats with
fatty liver disease . -
pubmed
A therapeutic dosage ( 0.1 mg / kg ) and a toxic dose ( 15 mg / kg ) of
haloperidol were administrated to normal 9 - week - old male
rats or those with severe
fatty liver disease , and the blood concentration of
haloperidol was determined 15 min , 1 , 2 , and 3 h following
haloperidol administration . -
pubmed
When given at the therapeutic dosage , the concentrations of
haloperidol in both the blood and organs of the
rats with
fatty liver disease were significantly higher than those in the normal
rats . -
pubmed
However , when given at the toxic level , the blood and organ
haloperidol concentrations 1 h after administration tended to be lower in the
rats with
fatty liver disease than those in the normal
rats ; these lower
haloperidol levels returned to be the levels in the normal
rats 3 h after the administration of
haloperidol . -
pubmed
However , the volume did not change after the toxic or the therapeutic dose of
haloperidol compared with pre - administration in
rats with severe
fatty liver disease , although it was significantly higher than in the normal
rats . -
pubmed
The pathway for
haloperidol metabolism might have been saturated before the administration of
haloperidol in
rats with
fatty liver disease ; thus , it is possible that the blood concentration of
haloperidol tends to be much higher in
individuals with severe
fatty liver disease than in those with normal livers in an inverse proportion to the dosage of
haloperidol . -
pubmed
Phase 2 study of
rituximab plus
ABVD in
patients with newly diagnosed classical
Hodgkin lymphoma . -
pubmed
In the present study , we evaluated the efficacy and safety of
rituximab in combination with standard
doxorubicin ,
bleomycin ,
vinblastine , and
dacarbazine (
RABVD ) in
patients with
classical Hodgkin lymphoma (
cHL ) . -
pubmed
In this phase 2 study ,
patients with chemotherapy - naive , advanced - stage
cHL were treated with
rituximab 375 mg / m(2 ) weekly for 6 weeks and standard ABVD for 6 cycles . -
pubmed
Our results demonstrate that the addition of
rituximab to
ABVD is safe and has a promising clinical activity in
patients with advanced - stage
cHL . -
pubmed
19 studies focused on samples with a majority of
dysthymic patients . -
pubmed
Our 20 - year - old
patient presented with
cardiovascular collapse , raised anion gap
metabolic acidosis and
non - ketotic hypoglycaemia . -
pubmed
All
patients with persistent severe
CVS should have metabolic investigations to exclude
disorders of fatty acid oxidation . -
pubmed
Zebrafish share many gene functions with other
vertebrates including
humans , making
zebrafish a useful system for studying
cancer etiology . -
pubmed
Cognitive remediation in
schizophrenia : efficacy and effectiveness in
patients with early versus long - term course of illness . -
pubmed
Subdural hemorrhage in pediatric
patients with
enlargement of the subarachnoid spaces . -
pubmed
Therefore , the authors evaluated the frequency of
SDH in a cohort of
children with
enlargement of the subarachnoid spaces . -
pubmed
The authors excluded
children who had enlargement of the subarachnoid spaces diagnosed on imaging performed for
trauma or
developmental delay , as well as children with a history of
prematurity , diagnosis of intracranial pathology , or metabolic or
genetic disorders . -
pubmed
Chart review recovered the following data :
patient demographics , head circumference , history of
head trauma , and head imaging results . -
pubmed
For the subset of
children with
SDH , information regarding evaluation for other injuries , including skeletal survey , ophthalmological examination , and child protection team evaluation , was abstracted . -
pubmed
RESULTS : There were 177
children with
enlargement of the subarachnoid spaces who met the inclusion criteria . -
pubmed
Subdural hemorrhage was identified in 4 ( 2.3 % ) of the 177
children . -
pubmed
All of the
children with
SDH underwent evaluations for suspected nonaccidental
trauma , which included consultation by the child protection team , skeletal survey , and ophthalmological examination . -
pubmed
Evidence of additional
injuries concerning for
physical abuse were identified in a quarter of the
children with
enlargement of the subarachnoid spaces and
SDH , suggesting that an evaluation for suspected
nonaccidental trauma including occult
injury screening should be performed in cases of
SDH with enlargement of the subarachnoid spaces . -
pubmed
They were classified as
MCI or
AD patients . -
pubmed
Predictors of good functional outcome in counterpulsation - treated recent
ischaemic stroke patients . -
pubmed
Among all 207 recruited cases , 119 ( 57.5 % )
patients had a good outcome at 3 months after
stroke . -
pubmed
In
humans , their dysfunction has been linked to diseases , such as
hypertension ,
heart failure and
epilepsy , and they are well - established drug targets . -
pubmed
Vaccines are predicted to play an important role in
H5N1 control should the virus become readily transmissible between
humans . -
pubmed
Children with
neurodevelopmental disorders are at increased risk for sleep issues , which affect quality of life , cognitive function , and behavior . -
pubmed
To determine the prevalence of
sleep problems in
children with the common
neurodevelopmental disorder neurofibromatosis type 1 , a cross - sectional study was performed on 129 affected subjects and 89 unaffected siblings , age 2 to 17 years , using the Sleep Disturbance Scale for
Children questionnaire . -
pubmed
Children with
neurofibromatosis type 1 were significantly more likely to have disturbances in initiating and maintaining sleep , arousal , sleep - wake transition , and
hyperhidrosis , but not problems with
abnormal sleep breathing , or excessive
somnolence . -
pubmed
We tested for this association in a case - control study in 100 Iranian sporadic
LOAD patients based on diagnostic criteria of
DSM - IV - TR and NINCDS -
ADRDA and in 100 normal controls without any personal and family history of
AD or other related
dementias . -
pubmed
Our study demonstrated that T - carrying genotype frequency in
AD patients is significantly higher than in controls and there was a 2.5 - fold increased risk for developing
AD in the T - carrying genotype compared to C / C genotype ( odds ratio = 2.5 , p = 0.010 ) . -
pubmed
Lung cancer is the primary cause of
cancer - related mortality worldwide and although improvements in treatment have been achieved over the last few years , long - term survival rates for
lung cancer patients remain poor . -
pubmed
This article describes a 55 - year - old
man with a well - delimited , oval - shaped ,
radiolucent lesion , occupying the middle and apical third of teeth 22 and 23 . -
pubmed
MATERIALS AND METHODS : Fifty - six
boys with severe
haemophilia A and B and 56 healthy peers between the ages of 7 - 12 in need of primary dental extraction were chosen for this study . -
pubmed
Effect of
cefepime dose on mortality of
patients with Gram - negative
bacterial bloodstream infections : a prospective cohort study . -
pubmed
We evaluated the effect of
cefepime on the mortality of
patients with
GNB bloodstream infections (
BSIs ) . -
pubmed
METHODS : A prospective cohort study was conducted in adult
patients with
creatinine & lt;=1.5 mg / dL who received empirical therapy with
cefepime for at least 48 h for
BSIs caused by
GNB . -
pubmed
CONCLUSIONS : High - dose
cefepime therapy was associated with lower mortality rates in
patients with GNB
BSIs , even for GNB with low
cefepime MICs . -
pubmed
METHODS : Four
patients with
Hailey - Hailey disease were examined by RCM . -
pubmed
Characterisation of
pyrazinamide - resistant
Mycobacterium tuberculosis strains isolated in Poland and Germany . -
pubmed
Although the majority of the
cancer studies have focused on the functions of protein - coding genes , emerging evidence has started to reveal the importance of the vast non - coding genome , which constitutes more than 98 % of the
human genome . -
pubmed
A number of non - coding RNAs ( ncRNAs ) derived from the ' dark matter ' of the
human genome exhibit
cancer - specific differential expression and/or genomic alterations , and it is increasingly clear that ncRNAs , including small ncRNAs and long ncRNAs ( lncRNAs ) , play an important role in
cancer development by regulating protein - coding gene expression through diverse mechanisms . -
pubmed
RESULTS :
Growth retardation of
mouse zygotes was greater in 20 %
O2 than 5 % , a sequential media design was superior to static simple media designs , but the supplementation of simple media with mixed
amino acids mitigated this difference . -
pubmed
OBJECTIVE :
Hepatitis C virus (
HCV ) has emerged as a leading cause of
chronic hepatitis ,
liver cirrhosis and
hepatocellular carcinoma worldwide . -
pubmed
The purpose of this study was to describe the distribution pattern of
HCV genotypes in
chronic hepatitis patients in the Campania region of southern Italy and estimate their association with risk factors and viral load . -
pubmed
CONCLUSION : The present study revealed that
HCV genotypes 1 and 2 accounted for over 95 % of all
HCV infections in the Campania region , and genotype 1 was more frequently associated with a higher viral load when compared to genotypes 2 and 3 . -
pubmed
Rarely ,
patients may present with two distinct
pituitary tumors . -
pubmed
To date , the
patient has been followed - up for 3 years without medical intervention and without
visual deterioration . -
pubmed
Thrombocytopenia affects
patients undergoing liver transplantation . -
pubmed
Graft and overall survival in
patients with different degrees of
thrombocytopenia and with or without intraoperative platelet transfusion were described . -
pubmed
However , the utility of this technique for
parapharyngeal abscesses in paediatric
patients has not been investigated . -
pubmed
This paper describes an intraoral drainage technique combined with tonsillectomy for treating
children with a
parapharyngeal abscess that obviates the need for skin incision . -
pubmed
In addition , both
patients suffer from a
polyneuropathy . -
pubmed
Safety of
ferric carboxymaltose immediately after
infliximab administration , in a single session , in
inflammatory bowel disease patients with
iron deficiency : a pilot study . -
pubmed
IBD patients were recruited consecutively in the outpatient clinic in two groups . -
pubmed
All
patients received 5mg / kg IFX and 1000 mg FCM for
iron - restricted
anemia ( IRA ) or 500 mg FCM for
iron deficiency without
anemia . -
pubmed
RESULTS : All 45
patients ( 35
Crohn s disease , 10
ulcerative colitis ) received
IFX 5mg / kg . -
pubmed
CONCLUSION : Single - session administration of
FCM after IFX was safe and effective in
IBD patients and can offer a good cost - benefit ratio and improve treatment adherence . -
pubmed
The genetic basis of
SSB is almost wholly unknown in non -
human animals , though this is key to understanding its persistence . -
pubmed
CONCLUSIONS : Compared with conventional (
steroid or placebo injection ) therapy , BTX injections have beneficial effects for adult
patients with
shoulder pain , evidenced by improved
pain scores and ROM . -
pubmed
Autism characteristics in sixty
children ( aged from 2 to 8) were assed . -
pubmed
The liver fluke
Opisthorchis felineus is a member of the
triad of epidemiologically important liver fluke species belonging to the family Opisthorchiidae and the major agent causing
opisthorchiasis over a vast territory , covering Russia , Kazakhstan and several European countries . -
pubmed
The International Agency for Research on
Cancer classified
O. - pubmed
Here , we investigated the link between altered
breast cancer metabolism and AI resistance using AI - resistant and sensitive
breast cancer cells ,
patient tumor samples , and AI - sensitive
human xenografts . -
pubmed
There was no significant difference in prevalence of
infection or heavy - intensity
infection of either schistosome species between attending and non - attending children , apart from heavy - intensity
S. - pubmed
METHODS : A retrospective analysis was conducted of 163 locally advanced unresectable consecutive
pancreatic adenocarcinoma patients who received chemoradiotherapy in Zhejiang
cancer hospital from January 2009 to December 2011 . -
pubmed
Patients with higher MDW had a 1.48 - fold increased risk of
death compared to those with low MDW . -
pubmed
CONCLUSIONS : MDW is an independent negative prognostic factor for overall survival in
pancreatic adenocarcinoma patients . -
pubmed
Optimal revascularization strategy in
patients with multi - vessel
coronary artery disease remains a matter of debate , with advantages and disadvantages in both surgical and percutaneous procedures . -
pubmed
[
Sepsis associated
encephalopathy is an independently risk factor for nosocomial
coma in
patients with supratentorial
intracerebral hemorrhage : a retrospective cohort study of 261
patients ] . -
pubmed
OBJECTIVE : To investigate whether the presence of
sepsis associated
encephalopathy (
SAE ) would predict nosocomial
coma (
NC ) and poor outcome in
patients with supratentorial
intracerebral hemorrhage (
SICH ) . -
pubmed
The adult acute
SICH patients with or without
coma admitted to intensive care unit ( ICU ) of Shuyang People ' Hospital Affiliated to Xuzhou Medical University from December 2012 to December 2015 were enrolled . -
pubmed
Univariate and Cox regression analyses were performed to analyze whether SAE would predict
NC and poor outcome in
patients with
SICH . -
pubmed
RESULTS : A total of 330
patients with acute
SICH and
coma were enrolled , excluding 60 cases of infratentorial
cerebral hemorrhage , 3 cases of primary
intraventricular hemorrhage , and 6 cases of unknown volume
hematoma . -
pubmed
It was shown by Cox regression analyses that
SAE [ hazard ratio ( HR ) = 3.5 , 95 % confidence interval ( 95%CI ) = 1.346 - 6.765 , P = 0.000 ] and SOFA score ( HR = 1.8 , 95%CI = 1.073 - 1.756 , P = 0.008 ) were independent risk factors of
death of
SICH patients with
NC , and
hematoma enlargement was independent risk factor of
death of
SICH patients with
PC ( HR = 3.0 , 95%CI = 1.313 - 5.814 , P = 0.000 ) . -
pubmed
One
patient experienced an intra - abdominal
abscess potentially related to delayed perforation as a
postoperative complication . -
pubmed
HAEC was the first clinical manifestation in 25 ( 61 % ) of the
patients with
HD . -
pubmed
Time is the enemy : Mortality in
trauma patients with
hemorrhage from
torso injury occurs long before the " golden hour " . -
pubmed
CONCLUSION : In
patients with high - grade
torso injury ,
AIS grades & gt;=4 , the degree anatomic disruption is associated with significant
hemorrhage . -
pubmed
In our study , a precipitous rise in
patient mortality was exhibited in this high - grade
injury group at prehospital times & lt;30 min . -
pubmed
Our data highlight the critical nature of prehospital time in
patients with non - compressible torso
hemorrhage . -
pubmed
METHODS : Fifty - four
patients with primary
Sjogren syndrome , 35
patients without primary
Sjogren syndrome ( patients with
dry mouth and
dry eye symptoms ) , and 52 healthy control volunteers were included in this study . -
pubmed
Patients with primary
Sjogren syndrome were classified as early or advanced stage by labial gland biopsies . -
pubmed
Hypogonadotropic Hypogonadism in
Males with
Glycogen Storage Disease Type 1 . -
pubmed
Case Studies and Methods : Four unrelated
patients with
GSD 1a ( N = 1 ) and 1b ( N = 3 ) were found to have
hypogonadotropic hypogonadism diagnosed at different ages . -
pubmed
In addition , all
patients were found to have disproportionately
low bone mineral density at the lumbar spine compared to the hip . -
pubmed
Common to all
patients was erratic metabolic control , including recurrent
hypoglycemia and elevated
lactate levels . -
pubmed
Patients with and without
NLS were compared using the chi2 - test or Mann - Whitney U - test . -
pubmed
Patients with
NLS showed significantly higher maximum
pain scores at every measurement time point : average difference ( = 3 , adjusted p & lt ; 0.005 ) , a higher impairment due to
pain ( = 15 , adjusted p & lt ; 0.005 ) , more
anxiety ( = 3 , adjusted p & lt ; 0.005 ) ,
depression ( = 3 , average adjusted p & lt ; 0.003 ) and
kinesiophobia ( = 4 , preoperative not significant , average postoperative adjusted p = 0.004 ) . -
pubmed
In
patients with
CPSP ,
NLS occurred significantly more often ( 74 % ) than in patients without clinically relevant
pain ( 17.5 % . -
pubmed
CONCLUSION : The occurrence of
NLS is associated with higher
pain scores , more impairment due to
pain and a higher psychosocial burden and they are more frequent in
patients with
CPSP . -
pubmed
PATIENT CONCERNS , DIAGNOSES , INTERVENTIONS , AND OUTCOMES : Here we report an FD
patient with widespread gastrointestinal
angiokeratomas who developed life - threatening
bleeding following anticoagulation for
atrial fibrillation . -
pubmed
LESSONS : Careful observation for
gastrointestinal bleeding is warranted for
patients on anticoagulation with extensive
cutaneous angiokeratomas . -
pubmed
Furthermore , our experience suggests that surveillance is needed to assess the prevalence and extent of
gastrointestinal angiokeratomas in
patients with
FD . -
pubmed
Here , we used
rabbit articular chondrocytes as a cellular model to investigate the effects and regulatory mechanisms of OA on dedifferentiation and pro -
inflammation . -
pubmed
Diffusion tensor imaging findings suggestive of
white matter alterations in a
canine model of
mucopolysaccharidosis type I. -
pubmed
Methods Four unaffected canines and two
canines with
MPS were euthanized at 18 weeks of age . -
pubmed
These findings suggest that the
canine model parallels
MPS in
humans , and further indicates that quantitative DTI analysis of such
animals may be suitable for future study of
disease progression and therapeutic response in
MPS . -
pubmed
METHODS : We retrospectively reviewed 34
patients with symptomatic
lumbar ganglion cysts treated with spinal canal decompression with or without spinal fixation . -
pubmed
Then ,
ethanol fermentation using the ethanologenic bacterial
strain Z. - pubmed
INTRODUCTION : Extracorporeal membrane oxygenation ( ECMO ) provides mechanical pulmonary and circulatory support for
patients with
shock refractory to conventional medical therapy . -
pubmed
Blood - Brain Barrier and Intrathecal Immune Response in
patients with
neuroinfections . -
pubmed
The aim of the study was to detect BBB permeability impairment and the intrathecal immune response in
patients with
CNS infections with various etiologies . -
pubmed
The purpose of this study was to analyze the correlation between
TS and risk / type of
recurrence in
EC patients , stratified according to the new European Society of Medical Oncology - European Society of Gynecological Oncology - European Society for Radiotherapy and Oncology classification . -
pubmed
METHODS : Data of
patients with histologically proven
EC who received primary surgical treatment between November 1999 and June 2015 were retrospectively retrieved from 5 institutions . -
pubmed
A total of 134 ( 11.5 % )
women had
recurrence : 47 ( 4 % ) of them had local
relapse , 30 ( 2.6 % ) had locoregional
relapse , and 57 ( 4.9 % ) had distant
relapse . -
pubmed
Tumor size 25 mm or greater emerged as the threshold for the prediction of a higher rate of local
recurrence ( P & lt ; 0.0001 , hazard ratio = 18.2 , P = 0.005 ) and a lower local
recurrence - free survival and
recurrence - free survival ( P & lt ; 0.0001 ) only in
patients with low - risk
EC . -
pubmed
CONCLUSIONS : In this very large series ,
tumor size emerges as an independent prognostic factor of local
recurrence in
women with low - risk
EC and could be a valuable additional criterion to personalize the treatment approach to these
patients . -
pubmed
METHODS : Retrievable markers were deployed into n = 28 FPAs of lightly embalmed
human cadavers . -
pubmed
OBJECTIVES : It is well - documented that geriatric
patients are at risk for serious
injuries after
fracture due to pre - existing medical conditions , physical changes of aging , and medication effects . -
pubmed
CONCLUSION : Frailty and surgical intervention are correlated with a higher 30 - day complication rate in
patients with
thoracic and thoracolumbar fracture . -
pubmed
Systematic literature review on patterns of pharmacological treatment and adherence among
patients with
bipolar disorder type I in the USA . -
pubmed
Currently , more than half of newly diagnosed
cancer patients receive radiation treatment . -
pubmed
RESULTS : In total , 7821
patients who underwent proximal aortic replacement from 47 studies were included : 8.3 % ( n = 649 ) had
Marfan syndrome (
MS ) . -
pubmed
Patients with apparently similar
tumours have variable outcomes . -
pubmed
Compression of the anterior visual pathways results in progressive thinning of the retinal nerve fiber layer ( RNFL ) and macular
ganglion cell complex ( GCC ) and this review will highlight the utility of OCT in evaluating
patients with this condition . -
pubmed
RECENT FINDINGS : The RNFL and macular GCC have been found to highly correlate with visual function in
patients with compressive
optic neuropathies . -
pubmed
Patients with an otherwise normal neuroophthalmic examination , including automated perimetry , may have macular GCC or RNFL thinning as the only manifestation of compression , enabling compressive
optic neuropathies to be diagnosed at an earlier stage and managed accordingly . -
pubmed
SUMMARY : Recent findings indicate that OCT is an important tool in the evaluation of
patients with compressive
optic neuropathies , particularly for prognosis in
patients with
visual field defects and diagnosis in
patients with preserved or mildly reduced visual function . -
pubmed
In this report , we describe a case of blunt perineal
trauma and partial
urethral disruption in a pediatric
patient presenting with refractory
anemia due to a
penile artery pseudoaneurysm . -
pubmed
Sclerosing angiomatoid nodular transformation of the spleen (
SANT ) in a
patient with
clear cell carcinoma of the uterus : a case report . -
pubmed
CASE PRESENTATION : A 49 - year - old Arabic
woman presented to our institute with
abdominal pain and distention . -
pubmed
The
patient underwent surgical treatment , and the histopathological examination of the resected uterine and splenic specimens disclosed invasive
uterine clear cell carcinoma and
sclerosing angiomatoid nodular transformation of the spleen , respectively . -
pubmed
We report the case of a
HIV - positive
patient with
type 2 diabetes mellitus who presented with uncontrolled blood
sugars after the initiation of prophylactic
isoniazid (
INH ) therapy . -
pubmed
The survival rate of
cancer patients remains unsatisfactory due to the late diagnosis , frequent
metastasis and poor response to chemotherapeutics . -
pubmed
In
cancer patients , it is often misdiagnosed as
metastasis . -
pubmed
CASE PRESENTATION : Here , we presented a case of a 50 - year - old female
patient suffering from slightly
headache who received
breast cancer modified radical mastectomy in 2004 , computed tomography and magnetic resonance imaging findings revealed abnormal lesions of diffuse skull which were misdiagnosed as skull
metastasis , and the relevant literatures were also reviewed . -
pubmed
In January 2018 , NIAID convened a workshop , entitled " 3 - D
Human in vitro TB
Granuloma Model " to advance the field . -
pubmed
Functional Improvement of Upper and Lower Extremity After Decompression and Neurolysis and Nerve Transfer in a Pediatric
Patient with
Acute Flaccid Myelitis . -
pubmed
BACKGROUND
Acute flaccid myelitis is an emerging
polio - like illness mostly affecting young
children , characterized by rapid onset of extremity
weakness and
paralysis in 1 or more limbs . -
pubmed
Certain viruses , including enteroviruses such as
EV-68 ,
EV-71 ,
poliovirus , and
West Nile virus , can cause this disorder . -
pubmed
CONCLUSIONS We demonstrated that decompression , neurolysis , and nerve transfer surgical procedures can be used successfully to correct the paralyzed upper and lower extremity movements in
acute flaccid myelitis patients . -
pubmed
We considered three groups of subjects :
patients with a
brain AVM before treatment using gamma knife radiosurgery ( GKR ) ;
patients three or more years post - GKR treatment ; and healthy volunteers . -
pubmed
Treatment of orthodontic
patients with
idiopathic condylar resorption (
ICR ) is challenging for clinicians due to the continuous change of occlusion caused by the unstable condylar position and symptoms in the temporomandibular joint (
TMJ ) . -
pubmed
In this case report , a
patient with
Class II open bite and progressive
condylar resorption was treated with an appropriate treatment protocol . -
pubmed
The approved dose of oral anticoagulant
rivaroxaban for
patients with
non - valvular atrial fibrillation (
NVAF ) in Japan is 15 mg once daily ( od ) in
patients whose
creatinine clearance is & gt;= 50 mL / min , but recent real - world studies have demonstrated that these
patients often received less than the recommended dose due to
bleeding concerns . -
pubmed
After adjusting for
patient characteristics by propensity scoring and inverse probability of treatment weighting , incidence rates of major
bleeding were comparable between under - dosed
patients and
patients who received the recommended dose ( 1.34 vs. 1.63 events/100 patient - years , p = 0.197 ) , although the incidence rates of
stroke / non - CNS
SE /
MI were higher in under - dosed
patients than in those who received the recommended dose ( 2.15 vs. 1.48 events/100 patient - years , p = 0.009 ) . -
pubmed
Predicting
postoperative fatigue in surgically treated
lung cancer patients in Norway : a longitudinal 5 - month follow - up study . -
pubmed
OBJECTIVES : Despite the negative influence of
fatigue on quality of life in
patients who undergo
lung cancer surgery , little is known about the possible predictors of
postoperative fatigue . -
pubmed
PARTICIPANTS : In total , 196 surgically treated
patients who answered the questionnaires both preoperatively and at 5 - month follow - up with valid
fatigue scores . -
pubmed
RESULTS : 45 studies were identified , including 2076 knee arthroplasty
patients , 620
patients with end - stage
osteoarthritis and 449 healthy controls . -
pubmed
The U.S.
Acute Liver Failure Study Group comprised of 33 tertiary care liver centers has enrolled consecutive
patients with
ALF or
acute liver injury (
ALI : INR>= 2.0 with no
encephalopathy ) , over two decades . -
pubmed
Short - term testicular warming under anesthesia causes similar increases in testicular blood flow in
Bos taurus versus
Bos indicus bulls , but no apparent
hypoxia . -
pubmed
Despite a long - standing dogma that
testicular hyperthermia causes
hypoxia , we reported that increasing testicular temperature in
bulls and rams enhanced testicular blood flow and
O2 delivery / uptake , without
hypoxia . -
pubmed
Our objective was to determine effects of short - term
testicular hyperthermia on testicular blood flow ,
O2 delivery and uptake and evidence of
testicular hypoxia in pubertal Angus (
B. - pubmed
Methods : We analyse demographic and clinical data from a cross - sectional survey of 400
HIV - infected patients aged > = 18 years , who were treatment - naive or switched
TDF regimen within over 3 years between November 2018 and March 2019 . -
pubmed
Computed tomography angiography of 155
patients who underwent TAVR using a SAPIEN 3 were used to identify patients with and without
thrombosis , and quantify
thrombus volumes . -
pubmed
The aim of this review is to provide an overview of the c - miRNAs suggested as promising biomarkers for
osteoporosis up until now , which could be helpful for early diagnosis and monitoring of treatment response , as well as
fracture risk assessment , in
osteoporotic patients . -
pubmed
Likewise , an increase in the lipid peroxidation and protein
carbonyls was also observed throughout the plant regardless the inoculated
strain , while
chlorophylls and
carotenes were increased only in those inoculated with
Bradyrhizobium sp . - pubmed
All these findings allowed us to conclude that the redox response of
peanut is conditioned by the rhizobial
strain , which contributes to the importance of effectively formulating bioinoculants for this crop . -
pubmed
Potentially inappropriate anticholinergic drug prescriptions for
patients with
Sjogren ' s syndrome . -
pubmed
A total of 4945
patients with
Sjogren ' s syndrome were identified , with a mean age of 64.6 + - 14.04 years and 75.7 % women . -
pubmed
Most
patients with
Sjogren ' s syndrome were women whose symptomatic management mainly included ocular lubricants with low use of oral
pilocarpine . -
pubmed
Similar hypoglycemic effects of glucomannan and its enzyme degraded products from
Amorphophallus albus on
type 2 diabetes mellitus in
mice and potential mechanisms . -
pubmed
In the present study , the
hypoglycemic effects of glucomannan ( AGM ) and its enzyme - degraded products from
Amorphophallus albus were investigated . -
pubmed
It was speculated that the hypoglycemic activity of AGM is decided by not the molecular weight but the glycosidic bonds /
monosaccharide composition of AGM , which might be structurally specific to the gut
bacteria , and thus certain
SCFAs and endogenous metabolites that are related to the occurrence and therapy of
T2DM . -
pubmed
While this is a rare occurrence we report , the incidental finding of
pacemaker lead malposition during a routine follow - up transthoracic echocardiogram and the benefits of three - dimensional transesophageal echocardiography in this
patient prior to lead extraction . -
pubmed
Additive manufacturing is a key technology required to realize the production of a personalized bone substitute that exactly meets a
patient 's need and fills a
patient - specific
bone defect . -
pubmed
Cytomegalovirus (
CMV)-associated
portal vein thrombosis in a healthy , immunocompetent
man . -
pubmed
We present a previously healthy
man in his 30s who presented with typical viral prodrome symptoms and worsening
abdominal pain . -
pubmed
Three cases of
ischaemic cardio - vascular accidents are reported under progestative treatment ; the drug used was
chlormadinone acetate ( 0,5 mg daily ) in one
patients , and
norethisterone ( 5 mg daily ) in two others . -
pubmed
Immunity to
malaria in many species , including
man , is acquired only after long exposure to
infection and is associated with chronic low - grade
parasitaemia . -
pubmed
Effect of
cimetidine on chronic
gastric ulcers produced experimentally in
rats . -
pubmed
The authors have studied the effects of
cimetidine on the healing of chronic
gastric ulcers induced in
rats . -
pubmed
The cell line on inoculation(ip ) in neonatal BALB / c
mice produced
lymphomic lesions in almost all the vital organs of the
mice . -
pubmed
Amyloidosis ,
hemochromatosis , and
atherosclerosis in a
roseate flamingo (
Phoenicopterus ruber ) . -
pubmed
Clinical findings and cranial CT scan identified
stroke in 315 admitted
patients at Taichung Veterans General Hospital from January 1 , 1989 to December 31 , 1989 . -
pubmed
The mean age of
patient with
cerebral infarction was 64.8 years , which was about 3.3 years higher than those with
cerebral hemorrhage ( mean age 61.5 years ) . -
pubmed
Tumor staging tended to be significantly more advanced in OG
patients ( chi - square = 9.054 ; df = 3 ; P = 0.026 ) . -
pubmed
Hypertrophy of smooth muscle occurs in various medical conditions and several methods are available for inducing it experimentally in laboratory
animals , especially in urinary bladder , small intestine and ureter . -
pubmed
The
hypertrophic response differs somewhat with the type of organ , the
animal species , the age of the subject , and the experimental procedure . -
pubmed
Because the response of lymphocytes from different lymphocyte compartments may vary , we compared the responses of
murine peripheral blood , splenic , Peyer 's patch , and mesenteric lymph node lymphocytes to a battery of mitogens after
thermal injury . -
pubmed
The 80 micrograms / ml concentration is 5 times that found in the serum of
subjects treated with 200 mg of
etodolac twice a day for 6 days , and 33 times the concentration in synovial fluid of
arthritic patients treated with
etodolac 200 mg twice a day for 7 days . -
pubmed
In this work we have analyzed the factors that could potentially account for the differential effect of
5 '- AdThd among various cell types :
647V ( a
human bladder cancer cell line ) ;
HU ;
SV - HU ( a SV40 - transformed
human urothelial cell line ) , and
C3H / 10T1 / 2 mouse embryo fibroblasts (
10T1 / 2 ) cells . -
pubmed
WN-25 , when injected intravenously , can cause the
death of
mice only if the function of the BBB is impaired . -
pubmed
Staphylococcus intermedius in
canine gingiva and
canine - inflicted
human wound infections : laboratory characterization of a newly recognized zoonotic pathogen . -
pubmed
aureus by the following characteristics : coagulation of
rabbit plasma at 4 h ( 26 versus 100 % , respectively ) ,
hemolysis of
sheep blood at 24 h ( 30 versus 79 % , respectively ) , and
mannitol fermentation at 24 h ( 4 versus 93 % , respectively ) . -
pubmed
Fourteen previously collected
strains of coagulase - positive staphylococci from infected canine - inflicted
human wounds were reanalyzed ; 3 of 14 ( 21 % ) isolates were
S. - pubmed
intermedius is a common
canine gingival flora and is responsible for some canine - inflicted
human wound infections , thus representing a newly recognized zoonotic pathogen . -
pubmed
We assume a compensated
metabolic Se - deficiency state in
mice under these nutritional conditions , which leads to expression of enhanced metabolic capacity when induced by stress . -
pubmed
Four of 132 consequtive
patients with
paraproteinemia and with an M - component presented exclusively with
neurological symptoms . -
pubmed
Based on these findings the pathogenesis of
neuropathy in
patients with
paraproteinemia is discussed , and it is concluded that although there is evidence for immune - mediated
neuropathy in the
patients , the histologic , immunohistochemical and clinical data are conflicting and the exact pathogenic pathway is still unknown . -
pubmed
To study the natural history of
scoliosis in institutionalized adults who have
cerebral palsy , we reviewed retrospectively the cases of fifty - one
patients . -
pubmed
All
patients had had penetrating
injuries of the heart , ascending aorta , or aortic arch 1 week to 4 years earlier , but only three had an early emergency operation . -
pubmed
Eleven
patients ( 35 % ) had
ventricular septal defects and seven ( 23 % ) had other types of
intracardiac fistulas . -
pubmed
The remaining 13
patients had
fistulas between the aorta and the main pulmonary artery or innominate vein . -
pubmed
Metoclopramide potentiates
d - amphetamine - induced
hypermotility and stereotypy in
rat . -
pubmed
Two
patients have been treated in this manner , and more than 3 years after the operations , both
patients were still improving neurologically without any evidence of
tumor recurrence . -
pubmed
In the present study , we produced hybridomas by fusing lymphocytes from 13
systemic lupus erythematosus patients with the
GM 4672 lymphoblastoid line . -
pubmed
A decreased number of marrow CFU - e and peripheral reticulocytes was observed in the
mice with relative
polycythemia induced by
dehydration as well as in the
mice with absolute
polycythemia induced by
hypertransfusion . -
pubmed
Starting 2 weeks later , 1 to 5 micrograms ( depending on
strain ) of
12 - O - tetradecanoylphorbol-13 - acetate (
TPA ) in 0.2 mL
acetone /
mouse was applied three times weekly to the shaved back for 20 weeks . -
pubmed
This treatment resulted in 51/57
animals developing
lung adenomas vs. 5/57 in the control
animals . -
pubmed
In control animals treated with
NPYR we observed 3/26
animals with
tracheal papillomas , and 6/26
animals with hepatic neoplastic nodules . -
pubmed
In addition , significantly elevated percentages of TdT+ bone marrow cells ( presumptive prothymocytes ) were present in NZB , NZW , and NZB / W
mice between 1 and 4 wk of age , with the highest mean peak levels occurring in the NZB
strain . -
pubmed
In contrast ,
PGF2 alpha , which is not therapeutically active against
autoimmunity in NZB / W
mice , had no detectable effect on TdT+ bone marrow cells or thymocytes in BALB / c or NZB / W
mice . -
pubmed
The results also raise the possibility that the therapeutic efficacy of exogenous
PGE1 in autoimmune NZ
strain mice may be related , at least in part , to its ability to rectify the abnormal development of these early lymphoid cells . -
pubmed
Abnormalities at the B - cell level in
patients with
Behcet ' s disease ] . -
pubmed
2nd communication : Use of
suprofen suppositories as an antipyretic in
children with
fever due to
acute infections / A single - blind controlled study of
suprofen versus
paracetamol . -
pubmed
The present randomized single - blind trial was performed to study antipyretic effect and tolerability of
alpha - methyl-4 -( 2 - thienylcarbonyl )- phenyl acetic acid (
suprofen ,
Suprol ) suppositories versus
paracetamol (
acetaminophen ) suppositories in pediatric
patients with
fever of various etiology . -
pubmed
Fluid intake behavior in
patients with
spinal - cord injury : prediction and modification . -
pubmed
Immunofluorescent techniques were used to follow the replication of the SF-4
strain of
bovine para - influenza 3 ( PI-3 ) virus in Madin - Darby
Bovine Kidney ( MDBK ) , secondary
bovine kidney ( BK ) ,
Embryonic Bovine Trachea ( EBTr ) cell cultures and experimentally infected
hamsters . -
pubmed
Infection was limited to the epithelial lining of the upper respiratory tract , trachea and bronchi of experimentally infected
hamsters . -
pubmed
[ State of the cardiovascular system in
patients with
osteoarthrosis deformans treated at the Khmel'nik health resort with
radon -
oxygen baths ] . -
pubmed
[ Studies on the hypoglycemic activity of
guava , sugar cane fibers and
pig 's pancreas on
diabetic patients ] . -
pubmed
[ Blood
copper content and its diurnal excretion in urine in
patients with
coronary atherosclerosis ] . -
pubmed
[
Glutatione in the blood of
patients with
atherosclerosis and the effect of
iodine therapy ] . -
pubmed
The effectiveness of
sultopride in
acute psychiatric syndromes with prominent
agitation was tested in
patients seen in the emergency department of a general hospital . -
pubmed
Structural adaptation of the vascular bed in the broad ligament of the
dog uterus has been studied at various time of the experimental
phlebohypertension . -
pubmed
Patients experiencing
hypotension in this group showed a sharp rise in NE , suggesting baroceptor - mediated adrenergic stimulation . -
pubmed
In all
patients sustaining
hypotension during therapy , postdialysis PRA was closely correlated with NE . -
pubmed
Quantitative investigation on the urinary excretion and metabolism of
3,4 - dimethoxyphenylethylamine in
schizophrenics and normal
individuals . -
pubmed
The
DMPEA content was measured in urine from healthy
persons , from
schizophrenics , and from psychiatric
patients without
schizophrenia hospitalized with the
schizophrenics . -
pubmed
DMPEA could be found neither in
schizophrenics nor in controls or healthy
persons . -
pubmed
All
strains reacted with
C. - pubmed
donovani strains from Sudan can not be distinguished from the Indian
strain L. - pubmed
Effects on renal function of a low -
nitrogen diet supplemented with essential
amino acids and
ketoanalogues and of hemodialysis and free protein supply in
patients with
chronic renal failure . -
pubmed
The effect of
N -( 2 - carboxyphenyl )- 4 - chloroanthranilic acid disodium salt (
CCA ) on spontaneous
autoimmune disorders in MRL / l
mice . -
pubmed
Cross - reactivity between
bacterial epitopes and cartilage components has been assumed to play a role in the pathology of bacterial - induced
arthritis models . -
pubmed
In this study , we report prominent proteoglycan ( PG ) depletion in Safranin - O stained ankle joint sections from collagen - induced
arthritic rats . -
pubmed
In vitro , PG fractions were able to stimulate T lymphocytes from these
arthritic rats . -
pubmed
These data suggest that cross - reactivity between
bacterial epitopes and
PG does not seem to be a key element in the onset of
joint inflammation in
bacterial - induced
arthritis . -
pubmed
We characterized structural and functional changes of these lipoproteins in six
patients with
cholesteryl ester transfer protein ( CETP ) deficiency . -
pubmed
Relation to age , sex , weight , height ,
diabetes , serum lipids and consumption of coffee ,
tobacco and
alcohol . -
pubmed
Sixty - three
patients with a DSM - III diagnosis of
chronic schizophrenia served as subjects . -
pubmed
Prediction of survival in
patients with suspected recurrent
cerebral tumors by quantitative
thallium-201 single photon emission computed tomography . -
pubmed
PURPOSE : To assess whether quantitative
201Tl single photon emission computed tomography ( SPECT ) can be used as a prognostic test in
patients with suspected recurrent
cerebral tumor , regardless of various combined therapies given . -
pubmed
METHODS AND MATERIALS : The study population consisted of 22
patients with grade 4 , 3 , or 2
glioma and 7
patients with solitary cerebral
metastasis . -
pubmed
Each
patient underwent 201Tl brain SPECT to differentiate recurrent
tumor from
cerebral radiation necrosis , because the prior computed tomography and/or magnetic resonance imaging showed a mass lesion with an irregularly enhanced rim in the irradiation field . -
pubmed
In
patients with grade 3
glioma or solitary cerebral
metastasis , survival time was definitely dependent upon 201Tl index values , that is , above or below the baseline index of 2.5 . -
pubmed
Grade 4
glioma patients , however , had a very short - term survival independent of 201Tl index values . -
pubmed
CONCLUSION : Quantitative
201Tl SPECT may be a useful tool for predicting survival of
patients with suspected recurrent
cerebral tumor and may be used in place of
fluorine-18 - 2 - deoxy-2 - fluoro - D - glucose (
18F - FDG ) scan . -
pubmed
Mutagenicity of an
organophosphate insecticide
acephate -- an in vivo study in
chicks . -
pubmed
The presented data confirm our earlier reports that the neonatal
chicken test system is a convenient model and can be used as an alternative to
mammalian systems for screening some environmental contaminants for
genotoxicity . -
pubmed
We investigated the effect of the selective
serotonin reuptake inhibitor
citalopram on uncontrolled crying in
stroke patients in a double - blind placebo - controlled crossover study . -
pubmed
The prognosis was good with only five
deaths due to progressive
respiratory disease in 48
patients with known follow - up ( 11 % ) . -
pubmed
In a double - blind , within - subject , crossover comparison , we recorded visual - evoked potentials ( VEP ) in 30 healthy
men during euglycemia and after 20 or 50 min of constant
hypoglycemia of 2.66 mM ( 47.9 mg / dl ) induced by HI and PI . -
pubmed
Antibodies to
human optic nerve in
Leber ' s hereditary optic neuropathy . -
pubmed
We have analysed serum from 69
LHON patients and their relatives , 58 controls and 14
patients with ischemic or compressive
optic neuropathy . -
pubmed
Splenic abscess due to
Salmonella heidelberg . -
pubmed
Human papilloma virus (
HPV)-induced
condylomata acuminata in both sexes , as well as
cervical dysplasias were treated locally with an ointment or a cream containing 25 mg
clomiphene citrate per gram for a fortnight . -
pubmed
The therapeutic response to the drug was demonstrated by the disappearance of
condylomata acuminata ( 100 % ) ,
HPV DNA in
cervical dysplasia ( up to 80 % ) , and
penile genital warts ( 75 % ) . -
pubmed
The effect of
NAC on mitogen - activated - lymphocyte blastogenesis in
C57B1 / 6 mouse splenocytes and ability of
NAC to protect lymphocytes against mitogen - induced
cytotoxicity was examined in vitro . -
pubmed
MRI - derived
spinal disc abnormalities were observed in three of the first four asymptomatic
volunteer subjects . -
pubmed
Growth and growth hormone secretion in
children with
cancer treated with chemotherapy . -
pubmed
RESULTS :
Growth hormone deficiency (
GHD ) was observed in 27 of 60
patients ( 45 % ) . -
pubmed
CONCLUSIONS : Chemotherapy as the sole form of treatment in
children with
cancer interferes with growth . -
pubmed
Bronchial allergen challenge with isolated major allergens of
Dermatophagoides pteronyssinus : the role of patient characteristics in the early
asthmatic response . -
pubmed
METHODS : In 30
patients with mild - to - moderate
asthma , the EAR was investigated after inhalation of an isolated major allergen of
Dermatophagoides pteronyssinus ( i.e. -
pubmed
CONCLUSION : In
asthmatic patients allergic to house dust mites the degree of nonspecific
bronchial hyperresponsiveness is the main determinant of early - phase bronchial responsiveness to allergen . -
pubmed
In a randomized , controlled trial , 62
patients ( 47
men and 15
women ) with severe
antisocial snoring , but no
sleep apnea , were allocated to one of three surgical treatments . -
pubmed
We report about an unusual case of a
rupture of the Achilles tendon in a
patient with
Haglund ' s exostosis and long term
achillodynia . -
pubmed
The proteins of 60 KDa showed varied cross reactions against sera of five kinds of
patients with other
parasitic diseases (
filariasis ,
hookworm diseases ,
paragonimiasis ,
ascariasis and
clonorchiasis ) . -
pubmed
Several virulence - related genes have been described for prototype enteroaggregative
Escherichia coli (
EAEC )
strain 042 , which has been shown to cause
diarrhea in
human volunteers . -
pubmed
This plasmid - borne virulence locus may represent an important set of virulence determinants in
EAEC strains . -
pubmed
After 6 - hr infusion at 10 mL / kg / hr , a commercial 2.72 %
amino acid/7.5 %
glucose solution with
electrolytes ( AG ) caused obvious phlebitic changes , such as loss of venous endothelial cells , inflammatory cell infiltration , and
perivascular edema , in all 6
rabbits because of its low pH ( 4.52 ) and high titratable acidity ( 22 mEq / L ) . -
pubmed
Prenatal treatment with
methylazoxymethanol (
MAM ) in
rats generates
animals with a diffuse
cortical malformation associated with hyperexcitability . -
pubmed
These alterations are reminiscent of the
cortical malformations associated with
epilepsy in
children . -
pubmed
We hypothesised that one of the mechanisms supporting hyperexcitability in
MAM rats could be the presence of abnormal cortical connections in the malformed cortex . -
pubmed
Butyrate and
glucose metabolism by colonocytes in experimental
colitis in
mice . -
pubmed
Colonocyte
butyrate metabolism was investigated in experimental
colitis in
mice . -
pubmed
A 6.5 - year - old
boy presented with
thrombocytopenia , Coombs ' positive
hemolytic anemia , and multiple small posterior cervical lymph nodes . -
pubmed
The typical patient is a middle - aged
man with complaints of
cough and
shortness of breath . -
pubmed
Often , the diagnosis is delayed , and
patients are treated for
asthma or
bronchitis . -
pubmed
A clone encoding
PAH was used for in vitro transcription / translation , followed by immunoprecipitation with sera from 94
APS I patients and 70 healthy controls . -
pubmed
Based on subjective evaluation of
acne , three subgroups of
patients were selected : A ) users where
acne improved or disappeared ; B ) users in whom
acne deteriorated , C ) users who newly developed
acne . -
pubmed
In 221
women ( 18.40 % ) , the extent of
acne remained unaltered whereas it increased ( subgroup B ) in only 30 women ( 2.50 % ) . -
pubmed
The
patient died with the clinical signs of
pulmonary insufficiency . -
pubmed
The correlation between presenting ST - segment
depression and the final size of acute
myocardial infarcts in
patients with
acute coronary syndromes . -
pubmed
The use of reperfusion therapy in
patients with ST elevation
acute coronary syndromes had been established . -
pubmed
This study of
patients with non - ST - elevation
acute coronary syndromes investigates the quantitative relationship between presenting ST
depression and final QRS changes in both of these subgroups . -
pubmed
The data strongly support the concept of graft - host interaction concerning adherence of
tumors and extravasation of
human melanoma cells . -
pubmed
BACKGROUND :
Medulloblastoma in late
adults ( older than 65 years ) is an exceptional occurrence ; in fact only 8 cases are reported with complete clinical notes in the literature . -
pubmed
METHODS : The authors describe a case of
medulloblastoma occurring in a 68 - year - old
man and analyzed cases reported in the literature . -
pubmed
RESULTS : The overall average age of the
patients was 72.8 years ( range 67 - 88 years ) , and the male prevalence of this
tumour ( 70 % of cases ) seems to be unrelated to age . -
pubmed
CONCLUSIONS : It is interesting to note that : 1 ) histological analysis revealed a classic type
medulloblastoma ( 88.8 % of cases ) similar to the
children : 2 ) site of the
tumor is lateral similar to the adults ( 77.7 % of cases ) . -
pubmed
Evaluation of the height from which
human fell from his / her tissue and
organ injuries is discussed . -
pubmed
TRANS F may be slightly more
hypercholesterolemic than
TRANS V or there may be other
hypercholesterolemic fatty acids in partially hydrogenated
fish oil than those included in the equations . -
pubmed
Recombinant vectors based on adeno - associated virus (
AAV ) or
human immunodeficiency 1 ( lentivirus ) are promising tools for long term in vivo gene delivery . -
pubmed
Managing poor performance
non - small - cell lung cancer patients . -
pubmed
Glucocorticoids and parental
hyperphagia in
ring doves (
Streptopelia risoria ) . -
pubmed
Collectively , these data support the hypothesis that
corticosterone contributes to the parental
hyperphagia exhibited by breeding
doves during the posthatching period . -
pubmed
INTRODUCTION : Accurate staging of the axilla for metastatic
disease is critical in deciding on the optimal management of
patients with
breast cancer . -
pubmed
Nontuberculous mycobacterial ( NTM ) infections are an increasingly recognized cause of
chronic lung disease in immunocompetent adults , and the
M. - pubmed
False - positive magnetic resonance imaging skeletal survey in a
patient with sporadic
hypophosphatemic osteomalacia . -
pubmed
[ Integral indices of peripheral blood leukogram in the estimation of non - specific immunological reactivity in
patients with
ischemic heart disease ] . -
pubmed
With the help of differential blood count analysis and velocity of erythrocyte sedimentation ( VES ) , 30 healthy persons ( donors ) , 30
patients with
chronic ischemic hearty disease (
IHD ) and 34
patients with
acute myocardial infarction (
AMI ) underwent the procedure of calculation for leukocyte index ( LI ) , leukocyte intoxication index ( LII ) , leukocyte shift index ( LSI ) , leukocyte and VES ratio ( LVESR ) , leukocytic and granulocytic index ( LGI ) , general index ( GI ) , neurophil - lymphocyte ratio ( NLR ) , neurophil - monocyte ratio ( NMR ) , lymphocyte - monocyte ratio ( LMR ) and lymphocyte - eosinophil ratio ( LER ) . -
pubmed
METHOD : The stance phase from heel - contact to toe - off of normal walking gait and after
tibialis posterior tendon rupture was simulated in eight roentenographically normal
human feet ( age 66 + /- 19 years ,
males ) . -
pubmed
EXPERIMENTAL DESIGN : Two ml of peripheral blood were collected from 55
cases with
hepatocellular carcinoma (
HCC ) , 20 cases with
chronic liver diseases devoid of
cancer , and 20 healthy
volunteers . -
pubmed
Cardiac transplantation has emerged as the therapeutic procedure of choice for
patients with
end - stage heart disease but the availability of donor organs remains major limiting factor allowing only 1 % of the candidates actually become transplant recipients . -
pubmed
The aim of this report is to summarize other currently available therapeutic alternatives for
patients with end - stage
cardiac disease . -
pubmed
[ Sequelae of resection of cervical sympathetic nerves in
dogs with unilateral
irritation of the diencephalon ] . -
pubmed
[ Action of
histamine on the tracheal cytograms of
mice subjected to
influenza infection ] . -
pubmed
[ Non - specific
mesadenitis in
children ] . -
pubmed
On some problems arising from the observation of the
infection with
Plasmodium berghei in
mice and
rats . -
pubmed
AIDS is one of the greatest
infectious disease threats to
human health despite the extensive efforts made since the discovery of
HIV in 1983 . -
pubmed
The use of plasmid DNA vaccination to elicit humoral and cell - mediated immune responses against
HIV infection has produced promising results in animal and in
human trials . -
pubmed
METHODS : 65
patients with
BD , 27 with
rheumatic diseases with
vasculitis , and 80 controls were studied . -
pubmed
Adverse mortality effect of central sympathetic inhibition with sustained - release
moxonidine in
patients with
heart failure (
MOXCON ) . -
pubmed
SALT - FREE and
rice diets for
hypertension . -
pubmed
Recapitulation of B cell differentiation in the central nervous system of
patients with
multiple sclerosis . -
pubmed
Although technical advances in the treatment of the elderly have resulted in improved
fracture fixation and surgical outcomes , clinical pathways have been developed to further improve
patient outcome while shortening hospital length of stay after
hip fracture . -
pubmed
We report on three
boys , two brothers and their maternal cousin , presenting with
dry hair ,
pilar keratosis , severe
hypodontia ,
smooth tongue ,
onychodysplasia , and
keratoderma and
hyperhidrosis of palms and soles . -
pubmed
Although effective in inducing
tumor - specific immunity in
mice and in some clinical trials ,
tumor - derived HSPs have many limitations like vaccines , such as the technical difficulty of ex vivo preparation of adequate quantities of HSPs from the resected
tumors of individual
patients . -
pubmed
Our findings may have broad relevance to the use of the in vivo HSP / suicide gene
tumor vaccine in therapy for
human solid tumors . -
pubmed
PURPOSE : The purpose of this research was to generate a
human monoclonal antibody specific to
gynecological cancers and to evaluate such an antibody as therapy for
gynecological cancers . -
pubmed
EXPERIMENTAL DESIGN : Transchromosomal KM
mice were immunized with the
human uterine
endometrial cancer cell line
SNG - S. -
pubmed
Hybridomas were constructed between spleen cells from KM
mice and
mouse myeloma cells . -
pubmed
Performance of
children diagnosed with
ADHD on selected planning and reconstitution tests . -
pubmed
Endothelial
calcium signaling in
rabbit arteries and its local alterations in early - stage
atherosclerosis . -
pubmed
This study is to examine whether endothelial
calcium signaling is different between
atherosclerosis - prone thoracic aortas (
TA ) and
atherosclerosis - resistant carotid arteries ( CA ) in normal
rabbits and how it changes in early - stage
atherosclerosis . -
pubmed
In the same
hypercholesterolemic animal , fatty streak formation was much more prominent in TA than in CA . -
pubmed
Cessation of smoking after
AMI was associated with a significantly lower risk of cardiac events in
patients with
MS ( HR 0.485 , 95 % CI 0.281 to 0.837 , p=0.009 ) but not in patients without
MS ( HR 0.618 , 95 % CI 0.330 to 1.157 , p=0.132 ) . -
pubmed
The first was a 78 - year old
woman who had a 2 - d history of
vomiting and
epigastralgia . -
pubmed
The second case was a 76 - year old
man with a 1 - wk history of
epigastralgia . -
pubmed
The procedure for the localization of fMRI areas was validated by direct cortical stimulation on 38 AVM and
tumor patients undergoing conventional surgery . -
pubmed
Indications for the procedure were
DVT or
PE and contraindication of anticoagulation in 141
patients ( 49.1 % ) ,
DVT or
PE and complication of anticoagulation in 65
patients ( 22.6 % ) , prophylaxis in 39 patients ( 13.6 % ) , massive
PE or poor respiratory function in 31 patients ( 10.8 % ) , paradoxal
emboli in 4
patients ( 1.4 % ) and other causes in seven
patients . -
pubmed
Symptomatic recurrent
PE occurred in 6
patients ( 2.1 % ) and was the cause of
death on 3 of them ( 1 % ) ,
DVT has been detected in 22
patients ( 7.7 % ) during the follow up period . -
pubmed
INTRODUCTION AND OBJECTIVES : In
patients with
pulmonary atresia with intact ventricular septum ( PAIVS ) , radiofrequency - assisted perforation of the valve is the most widely used initial therapy when the anatomy is favorable . -
pubmed
infection in
owl monkeys (
Aotus nancymae ) . -
pubmed
pinworms in
Aotus nancymae and other New World primates are typically subclinical , but
infection during experimental use could confound interpretation of experimental data . -
pubmed
Here , we report on a specific prognostic study on
stroke patients and describe how we explored the prediction performance of our model . -
pubmed
Combined effects of
hypoxia and endurance training on lipid metabolism in
rat skeletal muscle . -
pubmed
METHODS : Male
Wistar rats were exposed either to hypobaric
hypoxia ( at a simulated altitude of approximately 4000 m , PIO(2 ) approximately 90 mmHg ) or to normoxia ( sea level ) for 5 weeks . -
pubmed
Iodine is an essential nutrient for
humans as a critical constituent of thyroid hormones ; both
iodine deficiency and excess have adverse consequences for the thyroid gland . -
pubmed
Seven
patients with acute
optic neuritis and two
patients with
acute stroke were investigated . -
pubmed
RESULTS : The mean perfusion value for ROIs in gray matter was 62 mL/100g / min and 21 mL/100g / min in white matter in
patients with acute
optic neuritis . -
pubmed
The perfusion inside the
infarct core was 9 mL/100g / min in one of the
stroke patients . -
pubmed
RATIONALE : Exploring differences between
mouse strains in drug effects in models of antidepressant - like activity may provide clues to the neurobiology of antidepressant responses . -
pubmed
C57Bl/6
mice were more sensitive to
8 - OH - DPAT - induced
hypothermia . -
pubmed
Real - life effectiveness of
Singulair (
montelukast ) in 506
children with mild to moderate
asthma . -
pubmed
OBJECTIVES : To assess the efficiency of and satisfaction with Singulair in
asthmatic children under real - life conditions . -
pubmed
METHODS :
Montelukast was prescribed for 6 weeks to a cohort of 506
children aged 2 to 18 years with mild to moderate persistent
asthma , who were enrolled by 200 primary care pediatricians countrywide . -
pubmed
High rate of abortion and
developmental abnormalities is thought to be closely associated with inefficient epigenetic reprogramming of the transplanted nuclei during
bovine cloning . -
pubmed
PURPOSE : To study the reduction in
tumor size and the safety and efficacy of combined phacoemulsification and intravitreal
triamcinolone acetonide injection ( phaco - IVTA ) in
patients with treated
melanoma and
atypical nevi . -
pubmed
METHODS : The medical records of 49 consecutive
patients ( 51 eyes ) with treated
melanoma or
atypical nevi treated with phaco - IVTA were evaluated retrospectively for changes in Snellen visual acuity ,
tumor volume , and frequency of complications . -
pubmed
CONCLUSIONS : Combined phacoemulsification and IVTA was reasonably safe in
patients with treated
melanoma and
atypical nevi . -
pubmed
Intravitreal
triamcinolone acetonide injection at the time of
cataract surgery in
patients with treated
melanoma or
nevus may reduce rates of
tumor progression in these
patients . -
pubmed
Detection and description of spatial patterns of bacterial brown
spot of
snap beans using cyclic samples . -
pubmed
[ Successful functional hemispherectomy in adult
patients with
refractory epilepsy ] . -
pubmed
METHODS : We report our series of four adult
patients that have undergone functional hemispherectomy for their refractory
epilepsy . -
pubmed
One
patient had
Rasmussen encephalitis . -
pubmed
The fourth
patient has had more than 75 % reduction in
seizure frequency . -
pubmed
Early complications included an isolated
tonic - clonic generalized seizure ( one
patient ) , and
status epilepticus in another
patients related to
infection and use of
meropenem . -
pubmed
Only one
patient has presented
hemianopia as a permanent
neurological deficit after surgery . -
pubmed
CONCLUSIONS : Functional hemispherectomy is a good surgical option in the setting of large unilateral hemispheric lesions causing
hemiparesis and intractable
seizures , even in adult
patients . -
pubmed
Several studies indicate that
testosterone replacement therapy may produce a wide range of benefits for
men with
hypogonadism , including improvement in libido , bone density , muscle mass , body composition , mood , and cognition . -
pubmed
Time course of continuous positive airway pressure effects on central
sleep apnoea in
patients with chronic
heart failure . -
pubmed
Continuous positive airway pressure ( CPAP ) causes a variable immediate reduction in the frequency of central
apnoeas and
hypopnoeas in
patients with
congestive heart failure (
CHF ) and
central sleep apnoea (
CSA ) , but has beneficial mid - term effects on factors known to destabilize the ventilatory control system . -
pubmed
Preoperative use of inhaled
tiotropium in
lung cancer patients with untreated
COPD . -
pubmed
BACKGROUND AND OBJECTIVE :
Lung cancer patients with
COPD are at high risk during surgery . -
pubmed
METHODS : A retrospective review was performed of the medical records of 102
patients with
primary lung cancer and
COPD , who underwent scheduled surgery . -
pubmed
Twenty - one
lung cancer patients with untreated mild - to - severe
COPD received
tiotropium preoperatively . -
pubmed
CONCLUSIONS : Preoperative treatment with
tiotropium may facilitate surgical treatment for
lung cancer patients with
COPD . -
pubmed
This is encouraging for
COPD patients who may require curative lung resections . -
pubmed
However ,
pain - dependent immobilization may pose a serious hazard to
patients with severe preexisting co - morbidities . -
pubmed
METHODS : We retrospectively analysed 534
patients with these
injuries . -
pubmed
Notably eight
patients presented with
meningitis . -
pubmed
Fifteen
patients ( 42.8 % ) had inclusion
tumor with the
dermoid tumor being the most common . -
pubmed
Human - in -
mouse modeling of
primary head and neck squamous cell carcinoma . -
pubmed
METHODS :
HNSCC tissue was obtained from
patients at biopsy / resection , cultured , and implanted into
mice . -
pubmed
Histology and immunohistochemistry ( IHC ) were used to confirm
HNSCC and
human origin . -
pubmed
Xenograft modeling was attempted in primary
HNSCCs from 12
patients with a success rate of 92 % . -
pubmed
Immunostaining confirmed
human origin of epithelial
tumor cells within the modeled
tumor . -
pubmed
The high success rate of
human - in -
mouse tumor formation from primary
HNSCC suggests that selection pressures for
tumor growth in this model may be less than those observed for establishment of cell lines . -
pubmed
Contrary to our hypothesis , these results suggest that endurance training induced significant
impairment of regional systolic and diastolic LV myocardial function and ejection fraction in
rats . -
pubmed
There is virtually no literature on physiological changes in the brains of
children or adults with
cerebral palsy (
CP ) after an intervention . -
pubmed
It is unclear whether the principles of plasticity that have been deduced from
animal models of
stroke might also apply to
children and adults with
CP . -
pubmed
But
children with
CP should have the potential to respond to experience in a similar way to
adults , with the additional potential of regulation of neuronal development in response to
injury . -
pubmed
PURPOSE : To determine the magnitude of setup and organ motion errors from a subset of
prostate cancer patients treated with conventional conformal radiotherapy , and to estimate the CTV - PTV margin according to published margin recipes . -
pubmed
METHODS AND MATERIALS : Twenty
prostate cancer patients were treated with external radiotherapy using electronic portal images ( EPIs ) . -
pubmed
The
infection is either not transmitted at all or only under exceptional conditions by
turkeys in the early acute stage . -
pubmed
A few coccidia
cysts were found in two
turkeys and are referred to more in detail elsewhere . -
pubmed
nicotinamide ,
lactic acid ,
triethyl acetate /
ethyllineolate , and prebiotic
plant extracts , affect different mechanisms of
acne pathogenesis and therefore may contribute to a decrease in
acne lesions . -
pubmed
Soy Bowman Birk Inhibitor Concentrate ( BBIC ) is a known
cancer preventive agent now in
human clinical trials . -
pubmed
In a xenograft model of
nude mice transplanted with
human breast cancer MDA - MB-231 cells , intraperitoneal injections of lunasin , at 20 mg / kg and 4 mg / kg
body weight , decrease
tumor incidence by 49 % and 33 % , respectively , compared with the vehicle - treated group . -
pubmed
CONCLUSIONS / SIGNIFICANCE : We conclude that
lunasin is actually the bioactive
cancer preventive agent in BBIC , and BBI simply protects lunasin from digestion when
soybean and other seed foods are eaten by
humans . -
pubmed
israelensis (
Bti , H-14 serotype ; VectoBac ( ) WDG ) in the laboratory and also in the field against two principal
malaria vectors ,
Anopheles culicifacies and
Anopheles stephensi . -
pubmed
The
respiratory syncytial virus (
RSV ) is a primary cause of lower
respiratory tract infections in children , the elderly and in people who are immune suppressed , and is also the cause for the development of
asthma primarily in infants . -
pubmed
However , the immunological mechanisms by which
RSV enhances allergic sensitization and
asthma remain unclear . -
pubmed
We investigated the frequency of
CADASIL among selected
patients with
cerebral ischemia of the lacunar subtype . -
pubmed
METHODS : we studied
patients under 65 years old who presented
cerebral ischemia of the lacunar subtype without
hypertension ,
diabetes mellitus or other causes that explained the
cerebral ischemia . -
pubmed
We studied 30
patients , mean age was 53 years ( range 34 to 65 ) , 50 % were men and all patients suffered a
lacunar stroke . -
pubmed
Immunostaining analysis was positive in two
patients ( 6.6 % ) and the genetic analysis confirmed a mutation characteristic of
CADASIL in exon 4 nt 622C / T (
Arg 182
Cys ) and 694 T / C ( Cys206Arg ) respectively . -
pubmed
CONCLUSIONS :
CADASIL disease was present in 6.6 % of
patients younger than 65 years with a
lacunar stroke and without
hypertension or
diabetes mellitus . -
pubmed
Screening for
CADASIL should be considered in these
patients . -
pubmed
To help uncover the functional significance of macrophages in the context of
trypanosome infection , we determined the mRNA levels of genes associated with an increase in macrophage number or macrophage function in WS- and ILS - infected
rats and in
cultured cells . -
pubmed
Anemia occurs in ILS- , but not WS - infected ,
rats . -
pubmed
These results suggest that
anemia - induced
hypoxia in ILS - infected
rats stimulates the immune system and activates macrophages . -
pubmed
Carboplatin and
gemcitabine combination in metastatic triple - negative
anthracycline- and
taxane - pretreated
breast cancer patients : a phase II study . -
pubmed
The
carboplatin and
gemcitabine ( CG ) combination is active in unselected
anthracycline /
taxane pretreated metastatic
breast cancer patients , so we carried out a phase II study to evaluate the activity of the CG combination in pretreated metastatic
TNBC patients . -
pubmed
Grade 3/4
neutropenia occurred in 17 and
febrile neutropenia in 4
patients . -
pubmed
Ten
patients had Grade 3/4
thrombocytopenia . -
pubmed
The CG combination is a reasonable option for the treatment of metastatic pretreated
TNBC patients . -
pubmed
OBJECTIVE : Our goal was to determine the prevalence of
sexual dysfunction and identify risk factors associated with sexual morbidity in
patients with early stage
endometrial cancer . -
pubmed
METHODS : This prospective trial included
patients with
stage I - IIIa endometrial cancer , without evidence of disease , and one to five years out from primary surgical treatment . -
pubmed
Novel anti -
cancer role of
naphthazarin in
human gastric cancer cells . -
pubmed
This study is the first to investigate the anti -
cancer effect of
naphthazarin (
Naph ) , one of the
naphthaquinones , in
human gastric cancer AGS cells . -
pubmed
Treatment reduces the cryoglobulins that cause
vasculitis , yet it also leads to a transient increase in liver enzymes and
HCV genomic RNA in the periphery . -
pubmed
RESULTS : Sixteen
patients ( 15.5 % ) developed
DAIIS with the need for surgical intervention . -
pubmed
Aging independently of the hormonal status changes
pain responses in young postmenopausal
women . -
pubmed
The objective was to determine the efficacy and safety of
dexamethasone ointment in the treatment of recurrent
aphthous ulceration and detect serum
dexamethasone concentrations in the
patients . -
pubmed
There were 810
patients with minor recurrent
aphthous ulcerations screened for study eligibility , and 240
patients were enrolled at 5 centers from March 1 , 2009 to April 30 , 2010 ; 120 were assigned randomly to the treatment group and 120 to a control group . -
pubmed
Patients were instructed to apply the given agent to the identified
ulcer 3 times a day ( after meals ) for 5 days . -
pubmed
Structured multidisciplinary management enables it to be performed safely even in
patients with a
PM or
ICD . -
pubmed
BACKGROUND : Previous studies demonstrated that high fruit consumption was associated with a lower risk of cardiovascular events in
patients with
Type 2 diabetes mellitus . -
pubmed
We studied the relationship between dietary fruit intake and carotid intima - media thickness in
patients with
Type 2 diabetes . -
pubmed
METHODS : A total of 255 Chinese
patients with
Type 2 diabetes were recruited . -
pubmed
The method is demonstrated on both simulated and in vivo short - TE 1H MRSI data in
patients with
GBM . -
pubmed
In addition ,
mice bearing
HCT-8 - xenografted
tumors , which received intratumoral administration of the oncolytic adenovirus , showed significantly reduced
tumor growth and enhanced survival . -
pubmed
RESULTS : For full thickness
rotator cuff tears , MRI and arthroscopy detected them in 76 and 82
patients , respectively . -
pubmed
Clinical outcomes of
patients with
salivary gland carcinomas preoperatively misdiagnosed as benign lesions . -
pubmed
BACKGROUND : We compared clinical outcomes between
patients with
salivary gland carcinomas preoperatively misdiagnosed as benign lesion and properly diagnosed as malignant lesion . -
pubmed
CONCLUSIONS : The clinical outcomes of
patients with
salivary gland carcinomas misdiagnosed as benign are relatively favorable . -
pubmed
Hemiarthroplasty of the shoulder can be a safe and an effective treatment for
pain in
patients with
rheumatoid arthritis . -
pubmed
We report a
patient who presented with a discharging
sinus over the tip of the acromium which was created by the displacement of the prosthesis and
erosion of the AC joint and distal clavicle . -
pubmed
Implication of
limonene and
linalyl acetate in
cytotoxicity induced by
bergamot essential oil in
human neuroblastoma cells . -
pubmed
Bergamot (
Citrus bergamia , Risso et Poiteau ) essential oil ( BEO ) is a widely used
plant extract showing anxiolytic , analgesic and neuroprotective effects in
rodents ; also , BEO activates multiple
death pathways in
cancer cells . -
pubmed
Spraque - Dawley rats with bile duct ligation ( BDL)-induced
cirrhosis received vehicle (
citrate buffer ) or
streptozotocin (
diabetic , BDL /
STZ ) . -
pubmed
The survival rate of
cirrhotic rats was decreased by
STZ injection . -
pubmed
OBJECTIVES : The current study evaluated whether the functional connectivity pattern of the thalamo - cortical network in
patients with
Alzheimer ' s disease (
AD ) and
mild cognitive impairment (
MCI ) would show disease severityrelated alterations . -
pubmed
Second , the
MCI subjects were included to evaluate how different stages of disease affect the functional connectivity pattern of the thalamus . -
pubmed
Finally , a correlation analysis was performed between the strength of the functional connectivity of the identified regions and various clinical variables to evaluate the relationship between the strength of functional connectivity and the cognitive abilities of
MCI and
AD patients . -
pubmed
Functional connectivity between the bilateral thalamus and the identified brain regions of
MCI subjects was intermediate in comparison to the functional connectivity of
AD and
NC subjects . -
pubmed
CONCLUSION : Our results revealed disease severity - related alterations of the thalamo - default mode network and thalamocortical connectivity in
AD and
MCI patients . -
pubmed
Values of IC50 were calculated for complexes 3 and 4 against a panel of
human tumor cell lines representative of ovarian (
A2780 and
A2780cis ) and
breast cancers (
T47D ) . -
pubmed
This could lead to
mood disorders or altered response to any behavior influenced by
estradiol in
humans . -
pubmed
Monounsaturated fatty acids in serum
triacylglycerols are associated with response to neoadjuvant chemotherapy in
breast cancer patients . -
pubmed
The objective of this study was to perform comprehensive analysis of lipids in
breast cancer patient serum samples . -
pubmed
Lipidomic profiling using an established analytical platform was performed in two cohorts of
breast cancer patients receiving neoadjuvant chemotherapy . -
pubmed
The results suggest that the altered serum levels of
oleic acid in
breast cancer patients are associated with their response to chemotherapy . -
pubmed
Serologic tests for antibodies to
Blastomyces dermatitidis are not thought to be useful for the diagnosis of
blastomycosis , in part due to the low sensitivity of immunodiffusion and complement fixation . -
pubmed
dermatitidis surface protein BAD-1 were used for testing sera from
patients with proven
blastomycosis or
histoplasmosis and controls . -
pubmed
The antibodies were detected in 87.8 % of the
patients with
blastomycosis by the enzyme immunoassay compared to 15.0 % by immunodiffusion . -
pubmed
METHODS : Intracranial injection of the neurotoxin
6 - hydroxydopamine (
6 - OHDA ) was selectively lesioned into the nigrostriatal dopaminergic pathway in adult
Sprague Dawley rats , which is a common
rat model of
PD . -
pubmed
Caudal vertebral body fractures following lateral interbody fusion in nonosteoporotic
patients . -
pubmed
However , vertebral body
fractures have been reported after this procedure , particularly in
patients with
osteoporosis and
patients undergoing multilevel fusions . -
pubmed
We evaluated the risk factors for
caudal vertebral body fractures in 2 nonosteoporotic
patients with single - level disease . -
pubmed
CASE REPORTS : Two
patients presented with several years ' history of incapacitating
chronic low back pain and intermittent
radicular pain . -
pubmed
Both
patients returned several weeks later with excruciating
low back pain , without any postoperative history of
trauma or heavy lifting . -
pubmed
Diagnostic imaging in both
patients showed a
coronal fracture of the inferior vertebral body . -
pubmed
CONCLUSION :
Caudal vertebral body fracture in
patients with normal bone quality is a major potential complication after the minimally invasive lateral approach for lumbar fusions . -
pubmed
The results suggest that older
people present a heterogeneous
olfactory loss more specific to heavier molecules . -
pubmed
RESULTS : A 36 - year - old
woman at 14 weeks of gestation was admitted to the hospital for management of severe
hyperemesis gravidarum (
HG ) . -
pubmed
Physical examination revealed a confused , lethargic
woman with a normal - size thyroid and pendular
nystagmus in primary and lateral gaze . -
pubmed
CONCLUSION : This case demonstrates that
gestational thyrotoxicosis in a
patient with
HG can precipitate acute
WE , which may mimic
thyroid storm and thus delay appropriate management of this
neurologic disorder . -
pubmed
We conclude that prophylactic
thiamine administration may be considered before caloric replacement in
patients who present with
HG and acute
neurologic dysfunction . -
pubmed
Evaluation of the effect of
tranilast on
rats with
spinal cord injury . -
pubmed
We evaluated its ability to improve motor function and inhibit the spread of
tissue damage in
rats with
SCI . -
pubmed
The effect of vagus nerve stimulation on CSF
monoamines and the
PTZ seizure threshold in
dogs . -
pubmed
BACKGROUND : Vagus nerve stimulation ( VNS ) is an established treatment for
refractory epilepsy in
humans , but the precise mechanism of action ( MOA ) , predictive responsive factors and the optimal stimulation parameters remain to be elucidated . -
pubmed
One hour of VNS did not affect
seizure threshold in the
canine PTZ model . -
pubmed
The objective of this study was to examine whether reduced
inflammation is a possible mechanism for postoperative cognitive improvement in bariatric surgery
patients . -
pubmed
RESULTS :
Patients exhibited preoperative
cognitive impairment , although improvements 1 year postsurgery were seen in both attention / executive function ( mean [ M ; standard deviation { SD}]baseline = 53.57 [ 8.68 ] versus M ( SD)follow - up= 60.32 [ 8.19 ] ) and memory ( M [ SD]baseline= 44.96 [ 7.98 ] versus M [ SD]follow - up= 51.55 [ 8.25 ] ) . -
pubmed
Myiasis is a pathologic condition in
humans occurring because of parasitic infestation . -
pubmed
CONCLUSIONS :
HFRS patients have increased thrombopoiesis and platelet activation , which contributes to
intravascular coagulation . -
pubmed
BACKGROUND : Statin use in
individuals with
chronic obstructive pulmonary disease (
COPD ) with coexisting
cardiovascular disease is associated with a reduced risk of exacerbations . -
pubmed
These findings may ultimately lead to new and novel therapeutic targets for
patients with
COPD . -
pubmed
Human resting T - lymphocytes , T - lymphoblasts , and the
leukemic Jurkat T - cells all exhibit membrane
rupture above a critical membrane area expansion that is independent of either micropipette size or aspiration pressure . -
pubmed
METHODS : Ninety - nine consecutive
patients diagnosed and treated for
infectious SD between January 2007 to May 2015 were reviewed retrospectively . -
pubmed
We herein report the case of a 63 - year - old
female admitted to the hospital for ST elevation
myocardial infarction . -
pubmed
Clinical , radiological and biological findings oriented to a
pneumopathy and the
patient received the treatment for it . -
pubmed
A national retrospective study of paediatric
end - stage liver disease as a predictor of change to second - line therapy in
children with
autoimmune hepatitis . -
pubmed
METHODS : One hundred and seventy - one
children from 13 Canadian centres who fulfilled the International
Autoimmune Hepatitis Group ( IAIHG ) criteria were included and assessed for change to second - line therapy within 24 months of primary treatment onset . -
pubmed
Thrombocytosis in a
patient with
upper gastrointestinal bleeding . -
pubmed
Early - stage left
atrial intramural hemorrhage mimicking partial
coronary sinus thrombosis in a
patient who received ablation for
atrial tachyarrhythmias . -
pubmed
Human scabies ( infestation with the mite
Sarcoptes scabiei var hominis ) causes a significant disease burden worldwide , yet there are no agreed diagnostic guidelines . -
pubmed
Eligible studies were trials of therapeutic interventions against
scabies in
human subjects , published in English , enrolling patients with
scabies , and using various therapeutic interventions . -
pubmed
The validity of this observation is supported by an effect largely confined to those
patients with a
dilated pancreatic duct . -
pubmed
The nutritional status of
patients undergoing PD for
cancer needs further investigation and the effects of PERT require verification in further clinical studies . -
pubmed
We present a 68 - year - old
patient with multiple primary infiltrative
BCCs in the scalp area , initially treated 14 years ago with superficial contact X - ray therapy , end dose 60 greys , followed by electrocautery ( x2 ) several years later . -
pubmed
A 32 - year - old
man sustained an isolated
perforation of the gallbladder following blunt
abdominal trauma . -
pubmed
METHODS :
Lymphoma events ( up to March 2015 ) were identified from 19
tofacitinib studies ( 2 phase I , 9 phase II , 6 phase III , and 2 long - term extension ) of
patients with moderate to severe
RA . -
pubmed
Lymphoma incidence rates ( IRs ; number of
patients with events/100 patient - years ) and standardized incidence ratios ( SIRs ) were calculated . -
pubmed
CONCLUSION : In the
tofacitinib RA clinical development program ,
lymphoma rates were stable over time and there were minimal differences in the baseline characteristics of
patients with and without
lymphoma . -
pubmed
BACKGROUND : This study aimed to identify the clinical predictors of the degree of
right ventricular ( RV ) myocardial fibrosis in
patients with repaired
tetralogy of Fallot (
TOF ) with special focus on the RV pressure load . -
pubmed
Methods and Results : From April 2004 to March 2017 , 30
patients with repaired
TOF underwent pulmonary valve replacement and concomitant RV myocardial biopsy . -
pubmed
Patients with a right - to - left ventricular
systolic pressure ratio & gt;0.45 showed a significantly greater degree of RV
myocardial fibrosis under an equivalent
stroke volume ratio . -
pubmed
CONCLUSIONS : Under conditions of RV volume overload , a right - to - left ventricular
systolic pressure ratio & gt;0.45 was a predisposing factor for progression of RV
myocardial fibrosis in
patients with repaired
TOF . -
pubmed
pylori ) is one of the most prevalent
human pathogen and a persistent
infection with this bacterium causes common pathologies , such as
gastritis or
peptic ulcers , and also less common but more serious pathologies , such as
gastric cancer or
gastric mucosa - associated lymphoid tissue ( MALT ) lymphoma . -
pubmed
The clinical outcome of
gastrointestinal infection sustained by
H. - pubmed
It has been documented that Th1 , Th2 , Th9 , Th17 , Th22 and T regulatory ( Treg ) cells , separately or in coordination with each other , can affect the outcome of the
infection sustained by of
H. - pubmed
Findings : Thirty
patients aged & gt;= 60 years undergoing a radical operation of oral malignant
tumors with tissue reconstruction ( & gt;= 8 h ) were analyzed . -
pubmed
Titanium TSME appliance for
patients allergic to
nickel . -
pubmed
CONCLUSION : The non - allergic properties of
titanium allow to propose it as an alternative in
patients with a long - term history of
allergic reactions to nichel . -
pubmed
Here we study independent and interactive effects of cognitive regulation ( inhibition and sustained attention ) , temperament ( reactive and regulatory aspects ) , and maternal sensitivity ( as external regulation ) in a sample of 112 typically developing 10 - month - old infants ( 59
boys , 52.7 % ) , in relation to inattentive and
hyperactive / impulsive behavior at 3 years . -
pubmed
Complications of
pelvic and acetabular fractures in 1331 morbidly obese
patients (
BMI & gt;= 40 ): a retrospective observational study from the National Trauma Data Bank . -
pubmed
Conclusions : Morbidly obese
patients had higher rates of complications and longer hospital stays and were more likely to be discharged to rehabilitation facilities compared with control patients after pelvic ring or
acetabular fracture . -
pubmed
The ITS1 based geographical distribution studies indicated detection of environmental sequences similar ( 93 - 96 % ) to this
strain from
cattle faeces . -
pubmed
Differential proteomic analysis to identify proteins associated with
beak deformity in
chickens1 . -
pubmed
The beak is the dominant avian facial feature , and
beak deformity occurs in 0.5 to 2.5 % of some indigenous
chicken breeds , resulting in difficulties when eating , drinking , and performing natural behaviors . -
pubmed
A density model of neurovascular structures was generated from 28
human vastus lateralis muscles isolated from embalmed
cadavers . -
pubmed
In this report , we describe an extremely rare case of a
patient who suffered from
vertebral osteomyelitis caused by Peptostreptococcus micros . -
pubmed
Case Report : A 73 - year - old
man with a history of
diabetes mellitus was admitted to our hospital with a 5 - month history of severe
low back pain . -
pubmed
Effect of Electroacupuncture on Spermatogenesis in
Rats with
Oligozoospermia of
Insufficiency of Shen ( Kidney ) Essence Syndrome . -
pubmed
OBJECTIVE : To assess the effect of electroacupuncture ( EA ) on expression of cytoskeletal proteins from Sertoli cells ( SCs ) and spermatogenesis in
rats with
oligozoospermia of
insufficiency of Shen ( Kidney ) essence syndrome (
OIKES ) . -
pubmed
Reference tables with centiles of limb to body height ratios of healthy
human adults for assessing potential
thalidomide embryopathy . -
pubmed
Until nearly 30 years later in 1988 there were already over 10.000
children born with severe
birth defects ( e.g. -
pubmed
OBJECTIVES : We hypothesized that non - lytic
rifampicin compared with lytic
beta - lactam antibiotic treatment would attenuate the inflammatory response in
patients with
pneumococcal pneumonia . -
pubmed
RESULTS : Forty - one
patients with community - acquired
pneumonia were included ; 17 of them had
pneumococcal pneumonia . -
pubmed
Cytotoxicity test of film extracts was conducted with
L929 mouse fibroblasts , and the relative growth rate approached or exceeded 75 % , indicating an acceptable cytocompatibility . -
pubmed
How
cancer - specific mortality changes over time after radical cystectomy : Conditional survival of
patients with nonmetastatic
urothelial carcinoma of the urinary bladder . -
pubmed
METHODS AND MATERIALS : Within the SEER database ( 2004 - 2015 ) , we identified pTa / pTis / pT1N0 high grade , pT2 to pT4N0 and pTanyN1 - 3
patients treated with radical cystectomy for nonmetastatic
urothelial carcinoma of urinary bladder . -
pubmed
Methods : A total of 118 consecutive
patients with
CAVS were enrolled in the study ; 35
individuals without
aortic valve calcification were included in the control group . -
pubmed
Conclusion : The method to quantify
CX1003 in
human plasma was first exploited and validated with good sensitivity and specificity , and successfully fulfilled the requirement of the first - in -
human clinical pharmacokinetic study of
CX1003 in Chinese
patients with relapsed or metastatic
malignant solid tumors . -
pubmed
BVD in
sheep flocks . -
pubmed
Bilateral Basal Ganglia Lesions in a Dialytic
Patient with
Diabetes and Recurrent
Hypoglycemia . -
pubmed
External Validation of Pretreatment Pathological
Tumor Extent in
Patients with Neoadjuvant Chemoradiotherapy Plus Surgery for
Esophageal Cancer . -
pubmed
METHODS :
Patients with
esophageal cancer treated with neoadjuvant chemotherapy and esophagectomy between 2012 and 2015 were included . -
pubmed
Cell therapy stimulates bone neoformation in
calvaria defects in
rats subjected to local irradiation . -
pubmed
Background : The purpose of the study was to analyze the effect of cell therapy on the repair process in
calvaria defects in
rats subjected to irradiation . -
pubmed
Patients were followed for eight weeks after discharge for
relapse . -
pubmed
RESULTS : Over a 2 - year period , 215
patients developed nosocomial
CDI ( incidence 2:1000 ) and 200 ( mean age 62.2 + -19.6 years ) gave informed consent . -
pubmed
Recurrence occurred in 43
patients ( 21.5 % ) . -
pubmed
Changes in Cuticle Components and Morphology of ' Satsuma ' Mandarin (
Citrus unshiu ) during Ambient Storage and Their Potential Role on
Penicillium digitatum Infection . -
pubmed
To elucidate the role of fruit cuticle in
fungal infection , changes in cuticle composition and morphology of '
Satsuma ' mandarin during ambient ( at 25 C ) storage and their role in
Penicillium digitatum infection were investigated . -
pubmed
METHODS : We reviewed all
patients who underwent LTHE with extended lymph node dissection for distal esophageal
adenocarcinoma (
EAC ) at our institution between 2007 and 2016 . -
pubmed
Pre - operative characteristics , operative details ,
postoperative complications , and long - term outcomes were tracked by review of the electronic medical record and
patient surveys . -
pubmed
CONCLUSIONS : Laparoscopic transhiatal esophagectomy has an important role in current
esophageal cancer treatment and can be performed with curative intent in
patients with distal
esophageal tumors . -
pubmed
We aimed to explore the determinants of endothelial - dependent and -independent microvascular function progression over a 3 year period , in
people with and without both
diabetes and few clinical microvascular complications . -
pubmed
METHODS : Demographics were collected in 154
participants with
type 2 diabetes and in a further 99
participants without
type 2 diabetes . -
pubmed
RESULTS :
People with
type 2 diabetes had impaired endothelial - dependent microvascular response compared with those without ( AUC 93.9 [ 95 % CI 88.1 , 99.4 ] vs 111.9 [ 102.3 , 121.4 ] arbitrary units [ AU ] x min , p < 0.001 , for those with vs without
diabetes , respectively ) . -
pubmed
METHODS : Consecutive
patients with
atrophic gastritis or known
GIM were prospectively included . -
pubmed
Higher proportions of
patients with
GIM were detected by OE and
acetic acid versus random biopsy ( 60.5 % vs 35.5 % , 67.1 % vs 31.5 % , respectively ; P < 0.0001 for both comparisons ) . -
pubmed
A 58 - year - old
man is brought by the ambulance to the emergency department ( ED ) of a tertiary care centre following an out - of - hospital
cardiac arrest . -
pubmed
The electromagnetic radiation generated from mobile phones , radio - based stations , and phone towers , high - voltage power lines have been reported which leads to the variety of health scares such as the risk of
cancer in
human beings and adverse effects in animals , birds , etc . -
pubmed
As school districts across the United States consider how to safely operate during the 2020 - 21 academic year , CDC recommends mitigation strategies that schools can adopt to reduce the risk for transmission of
SARS - CoV-2 , the virus that causes
coronavirus disease 2019 ( COVID-19 ) ( 1 ) . -
pubmed
Further ,
patients ` characteristics were compared between benign and malignant
parotid lesions and between the two most common malignant
parotid lesions . -
pubmed
Out of 777 patients , 614 ( 78.9 % ) patients had a benign and 164 ( 21.1 % )
patients had a
malignant parotid lesion . -
pubmed
Patients with metastatic
cSCC were significantly older ( p < 0.001 ) and significantly more likely to be male ( p < 0.001 ) than patients with primary
parotid malignancies . -
pubmed
The present study shows the high prevalence of secondary
parotid malignancies in
patients who had received parotidectomy . -
pubmed
Ishigamide was isolated as a metabolite of a recombinant
strain of
Streptomyces sp . - pubmed
METHODS : We performed a retrospective review of 107
patients diagnosed with
plantar fasciitis who underwent ultrasound - guided release of the plantar fascia . -
pubmed
RESULTS : Heel
pain improved in 92.5 % ( 99 ) of
patients , but not in 7.4 % ( 8
patients ) . -
pubmed
In the group of
patients whose
heel pain improved , 9 experienced overload on the lateral column and dorsum of the foot , which improved with the use of plantar orthoses and a rehabilitation program . -
pubmed
One male
narcolepsy -
cataplexy patient was placed on the 60 - 30 schedule for 48 h. All subjects showed REM sleep during the schedule manipulation . -
pubmed
Pulmonary infection with
capsule - deficient cryptococcus neoformans . -
pubmed
A case of
bilateral lobar pneumonia due to
Crytococcus neoformans is presented . -
pubmed
In
diabetic animals there was no response over the 15 - min time period studied . -
pubmed
In
cats , horizontally transmitted viruses cause
leukemia and
lymphoma under natural conditions . -
pubmed
FOCMA , which is
FeSV - coded , is transformation and/or
tumor specific and expressed regardless of whether or not the cells make virus or contain virus structural antigens . -
pubmed
Lymphoid leukemia cells also express FOCMA , both when FeLV is used to induce the disease in laboratory
cats and when the
tumors occur under natural conditions . -
pubmed
FOCMA thus provides a useful model for antigens that might be expressed in " virus - negative "
leukemias of
man . -
pubmed
We studied the effect of
1 - beta - ribofuranosyl-1,2,4 - traizole-3 - carboxamide (
ribavirin ) on 66
patients with acute
viral hepatitis , by a double - blind study . -
pubmed
The results obtained demonstrated that the ovulation - inducing effect of a single administration of
estradiol benzoate ( EB ) to immature female
rats is not tantamount to the induction of
precocious puberty . -
pubmed
Cyclophosphamide ,
doxorubicin and
fluorouracil (
CAF ) plus
depo - buserelin in the treatment of premenopausal
women with metastatic
breast cancer . -
pubmed
A phase II study was undertaken to assess the effect of
CAF plus
depo - buserelin , as first - line treatment , in premenopausal
women with
breast cancer . -
pubmed
Twenty - nine
patients had metastatic
disease of one site , while 31 had 2 - 4 sites . -
pubmed
This study showed that
CAF plus
buserelin is well tolerated , with a very high response rate in selected premenopausal
patients with advanced
breast cancer . -
pubmed
In patients with acute , subacute , or chronic
sinusitis who are generally well except for persistent respiratory symptoms , of nasal discharge or
cough or both , the usual bacterial isolates are
Streptococcus pneumoniae ,
Haemophilus influenzae , an
Moraxella catarrhalis . -
pubmed
The effect of various types of operative interventions on the course of the early postoperative period was studied in 419
patients with
duodenal ulcer . -
pubmed
Two
subjects who had high titres of islet - cell autoantibodies ( ICA ) without clinical
diabetes produced
responsive T - cell lines . -
pubmed
Changes in vitreal
oxygen tension distribution in the
streptozotocin diabetic rat . -
pubmed
Measurements of vitreal
oxygen tension have been made for the first time in the
streptozotocin - induced
diabetic rat eye . -
pubmed
A total of 36
Sprague Dawley rats were divided into a control ( n = 18 ) and
streptozotocin injected group ( n = 18 ) , and after 5 - 6 weeks of established
hyperglycaemia , an acute experiment was performed in which vitreal
oxygen tension profiles were determined with
oxygen sensitive microelectrodes . -
pubmed
No significant difference was found in this mean mid vitreous value between the control
rats and
diabetic rats under the same systemic conditions . -
pubmed
We conclude that PD or
PEP when combined with FET have similar effects on short - term whole lung and regional TBC in
patients with
cystic fibrosis . -
pubmed
[ Experiences in the control of
brucellosis in
cattle herds in the government district of Hannover ] . -
pubmed
The tank milk screening of the dairy
cattle herds to detect antibodies against
Brucellosis ( and additional EBL and IBR ) has now become a standard method to continue the official status " free from ... " This is a safer and a more economic alternative to the previous blood sampling of
cattle older than two years with a three years interval because this method guarantees a safe information about the serological status of each
cow which is now tested at least once a year , depending on the time of dry standing status. -
pubmed
The levels of both peptides were normal in
patients with
hyperparathyroidism and those with
hypercalcemia due to various other causes . -
pubmed
We prospectively studied for three years the optical correction by contact lenses of 83 aphakic infants ( 141 eyes ) who generally also had systemic and other
ocular anomalies : 85 % of the
patients tolerated the lens wear for the whole study period . -
pubmed
Thirty - four eyes needed subsequent intraocular surgery , mostly minor , and nine
patients had
strabismus surgery . -
pubmed
It also suggests that an excessive
cadmium body burden alone may not be sufficient to induce
hypertension , but in
individuals whose blood pressure regulation may be impaired by other factors cadmium could stimulate the development of
hypertension . -
pubmed
This study also supports the recommendation to prevent
hypertensive subjects from being exposed to
cadmium . -
pubmed
Patients with low - stage disease ( clinical stage I ) were treated successfully with modified retroperitoneal lymph node dissection (
relapse rate , three of 40
patients ) . -
pubmed
Of nine
patients with retroperitoneal
tumors less than 3 cm in diameter , four
patients were satisfactorily treated with retroperitoneal lymph node dissection alone while five
patients required chemotherapy after retroperitoneal lymph node dissection . -
pubmed
Of 26
patients with retroperitoneal
tumors 3 to 5 cm in diameter , 17
patients were treated with chemotherapy alone . -
pubmed
The concentration of serum
glucose increased from 6.1 + /- 0.3 millimoles per liter ( 110 + /- 5 milligrams per deciliter ) in the control
animals to 31.1 + /- 0.8 millimoles per liter ( 560 + /- 15 milligrams per deciliter ) in the untreated
diabetic animals . -
pubmed
After two weeks of healing ,
fracture callus from the untreated
diabetic animals had a 29 per cent decrease in tensile strength and a 50 per cent decrease in stiffness compared with the controls . -
pubmed
Splenic abscess from
Fusobacterium nucleatum . -
pubmed
In
patients with
impaired renal function , use of population estimates resulted in less accurate dosing prediction , but this less accurate performance was not observed with use of the Bayesian forecaster . -
pubmed
This study determined whether the Achilles tendon reflex , H - reflex , and ankle range of motion ( ROM ) during ambulation undergo significant changes after application of
benzocaine spray applied to the triceps surae skin area of eight
stroke patients displaying
spasticity in ankle plantar flexor muscles . -
pubmed
We therefore studied 53
PSS patients with planar ( 201Tl )
chloride myocardial scintigraphy , and 44
PSS patients with radionuclide ventriculography using red blood cells labeled in vitro with
99mTc . -
pubmed
Thirty - four
patients with
bone tumours and
tumour - like abnormalities of the skeleton , of varying ages , were examined by a computer - aided diagnostic program ; the accuracy , clinical usefulness and specific advantages and disadvantages of the program have been evaluated . -
pubmed
The M / H ratios were high in
leprosy patients and they exhibited a further rise in
patients on treatment . -
pubmed
Reconsideration of the concept of enhanced static fusimotor drive in
rigidity in
patients with
Parkinson ' s disease . -
pubmed
The electromyographic responses elicited in the first dorsal interosseus muscle by small muscle stretches or by electrical stimulation of the median nerve were investigated in
parkinsonian patients and in age - matched healthy subjects . -
pubmed
Scrapie - induced
obesity in
mice . -
pubmed
Rats injected intraperitoneally with
magnesium pemoline avoided a buzzing sound ( conditioned stimulus ) associated with an electric
shock to the feet ( unconditioned stimulus ) more frequently than controls . -
pubmed
Drug - injected
rats did not avoid the foot
shock more frequently than controls , although the experi mental
rats did have shorter response latencies fn the active avoidance task . -
pubmed
Addition of
thallium acetate to infected cells ( at varying intervals of time after
infection ) to control
bacterial growth and conversion to the L phase during cellular disintegration decreased the number of positive L - form cultures obtained over a 10 - day period . -
pubmed
Comparison of the antibiotic sensitivity of bacteria recovered from infected tissue culture cells with the stock
strain of
Brucella abortus indicated that some resistance to
penicillin and
tetracycline had developed . -
pubmed
[ Monostatic localization of
bone dystrophy in
patients under hemodialysis for
chronic renal insufficiency ] . -
pubmed
Moose sickness , a
neurological disease of moose infected with the common cervine parasite ,
Elaphostrongylus tenuis . -
pubmed
Penicillin is still the antibiotic of choice for the treatment of uncomplicated
gonococcal urethritis in most of the United States , but the increasing incidence of penicillinase - producing
Neisseria gonorrhoeae ( PPNG ) in many areas of the world necessitates a reconsideration of standard therapy . -
pubmed
Comparison of
bluetongue type 20 with certain viruses of the
bluetongue and Eubenangee serological groups of orbiviruses . -
pubmed
Comparison of sedation ,
amnesia , and
patient comfort produced by intravenous and rectal
diazepam . -
pubmed
Recovery from sedation , experience during the postoperative course ,
amnesia , estimation of the sedative effect , and
patient preference of method of sedation were studied . -
pubmed
The degree of
amnesia was significantly higher during intravenous sedation , but a high degree of
amnesia was not related to
patients ' preference for a sedation method . -
pubmed
[ Acute
respiratory insufficiency in
children ] . -
pubmed
Food avoidance in
rats : the differential effects of
shock , illness and repellents . -
pubmed
The numerical behaviour of the leucocytes , thrombocytes and reticulocytes of 12
patients with
megaloblastic anaemia before and after additional transfusion as well as after following parenteral therapy with
vitamin B12 was investigated . -
pubmed
Excitation - contraction coupling in
mammalian cardiac muscle during
Ba2 + -induced
contracture . -
pubmed
The membrane potential and tension were recorded during
contracture of
mammalian ventricular muscles bathed in Tyrode
solution with
Ba2 + in the place of
Ca2 + . -
pubmed
Ulcerative colitis responsive to smoking and to
nicotine chewing gum in a
patient with
alpha 1 anti - trypsin deficiency . -
pubmed
For patients with smoking - responsive
ulcerative colitis , non -
tobacco forms of
nicotine delivery such as gum or transdermal patches should be considered to avoid the hazards of cigarette smoke . -
pubmed
For
patients with
ventricular septal defect and
mitral stenosis , a series of palliative procedures and operations are often required . -
pubmed
enhanced the protective action of
carbamazepine ,
diphenylhydantoin and
phenobarbital against maximal electroshock - induced
convulsions in
mice . -
pubmed
Intracranial venous thrombosis in a
patient with
multiple sclerosis . -
pubmed
A case is presented of a 35 - yr - old
woman with
multiple sclerosis who took
oral contraceptives and , subsequently , experienced intracranial transverse and sigmoid sinus
thromboses and , later , deep
venous thrombosis of the calf . -
pubmed
In addition , the diagnostic work - up and treatment options for
intracranial venous thrombosis are discussed , and appropriate birth control alternatives for disabled
patients , that is , diaphragm , sponges , condoms and
levonorgestrel , are reviewed . -
pubmed
Biopsies of colon mucous membrane obtained at colonofibroscopy of 16 adult
patients with
colon campylobacteriosis were studied . -
pubmed
Assessment of peripheral chemoreflex contributions to exercise
hyperpnea in
humans . -
pubmed
Most estimators of carotid chemosensitivity rely on the premise that , as the carotid bodies appear to be the sole mediators of the ventilatory response to
hypoxia in
humans , the entire ventilatory response to an
hypoxic challenge necessarily should be ascribed to carotid chemoreceptor activation . -
pubmed
PATIENTS AND METHODS : A total of 601
patients with
upper ureteric calculi underwent attempted RM . -
pubmed
One hundred eighty - eight
patients received a common
thromboembolic prophylaxis protocol with postoperative
aspirin , and had a standardized surveillance protocol to detect
thromboembolic complications . -
pubmed
Phylogenetic analysis of
feline immunodeficiency virus isolated from
cats in Taiwan . -
pubmed
Feline immunodeficiency virus was isolated from four
cats in Taiwan . -
pubmed
, the number of cross - links ) on the biodegradability behavior of these films using a
strain of
Pseudomonas aeruginosa was investigated . -
pubmed
[ Types of
hearing disorders in drug addicts and
individuals drinking non - consumable
alcohols ] . -
pubmed
Prophylactic administration of
clindamycin 2 % vaginal cream to reduce the incidence of spontaneous
preterm birth in
women with an increased
recurrence risk : a randomised placebo - controlled double - blind trial . -
pubmed
PARTICIPANTS : One hundred and sixty - eight
women with a singleton pregnancy and a history of a spontaneous
preterm delivery in the preceding pregnancy . -
pubmed
METHODS : A total of 1,350
patients with
cerebral aneurysms were operated in the Department of Neurosurgery at Santa Casa Hospital in Belo Horizonte from January 1982 to January 1998 . -
pubmed
All 74 DACA
aneurysms in the 72 operated
patients were completely clipped , including two giant
aneurysms . -
pubmed
In cases of
patients with multiple
aneurysms who require two different craniotomies , we propose two surgical stages , starting with the
aneurysm that has bled . -
pubmed
In the present study , we have developed a preclinical model of allogeneic HSC transplantation into
lymphoma - inoculated
mice , allowing us to directly test whether purified HSCs have measurable GVT activity . -
pubmed
The mechanism by which the GVT - conferring cells protect recipient
mice from
tumors was studied using immune defective
mice as donors . -
pubmed
Development of a long - term ascending
urinary tract infection mouse model for antibiotic treatment studies . -
pubmed
A model of ascending
unobstructed urinary tract infection (
UTI ) in
mice was developed to study the significance of the antibiotic concentration in urine , serum , and kidney tissue for efficacy of treatment of
UTI in general and
pyelonephritis in particular . -
pubmed
Strain
C175 - 94 achieved the highest counts in the kidneys , and this
strain was subsequently used as the infecting organism . -
pubmed
Use of the
mouse UTI model is feasible for study of the effect of an antibiotic in the urinary system , although the missing antibacterial effect in the bladder needs further evaluation . -
pubmed
RESULTS : Ten
patients in the group administered
Mydricaine , but no
patients in the control group , developed a
sinus tachycardia of & gt ; 100 beats / min for more than 10 min which was attributable to the mydriatic regime used . -
pubmed
The occurrence of this response was not predictable based on the
patients ' age , weight or the presence of
conjunctival erythema . -
pubmed
In an effort to identify
patients at risk , those with significant
hypersensitivity reactions were interviewed retrospectively . -
pubmed
Of these , 14
patients ( 9.3 percent ) suffered significant
hypersensitivity . -
pubmed
Detailed history in these patients revealed possible prior "
allergic sensitivity " in 78.6 percent of
patients . -
pubmed
In contrast , only 30 percent of 50 nonsymptomatic laser - treated
patients admitted to any positive
allergic tendencies . -
pubmed
The latter methodology is in advanced stages of development for application in
humans in the treatment of selected spinal fusions ,
fracture repairs , craniomaxillofacial surgery and
periodontal injury and disease . -
pubmed
BACKGROUND AND PURPOSE :
Generalized recessive dystrophic epidermolysis bullosa (
RDEB ) is a severe
inherited disease , in which
patients suffer from
blistering and
scarring of the skin and mucous membranes after minor
mechanical trauma . -
pubmed
The
subjects consisted of 27 cases of
CBD , 30 cases of
PSP , and 36 healthy controls ( CTL ) . -
pubmed
In
patients with
refractory angina , PMR did not cause immediate deterioration in hemodynamic status or regional LV function . -
pubmed
In recent years , a trend towards a decrease in male smoking has been noted , but there is still a high
tobacco exposure burden in both males and females , with a forecast of a further increase in rates of
lung cancer incidence and
deaths . -
pubmed
It also demonstrates advantages of the lumbal infusion test ( LIT ) as a part of the algorithm of the shunt operation in
patients with supposed pathology of
liquor malabsorption . -
pubmed
The treatment of
thoracic and lumbar spine fractures : a study of 123 cases treated surgically in 101
patients . -
pubmed
For a total of 123 thoracolumbar
traumatic lesions treated surgically in 101
patients over approximately 2 years ( all monitored clinically and radiographically up to consolidation by follow - ups after from 6 to 26 months , mean 10 months ) the technique used , complications and treatment are reported . -
pubmed
Neurologic deficit was caused by
fracture in 49
patients ( 40 % of the
fractures or 48 % of the
patients ) . -
pubmed
Six
patients out of 30 affected with
spinal cord lesion ( 20 % ) and 15 out of 19 affected with
cone and / or cauda lesion ( 79 % ) improved . -
pubmed
METHODS :
Rats received chemical
irritation of the prostate with or without pretreatment with
tamsulosin . -
pubmed
[ Epidural
hematoma as complication of subarachnoid anesthesia in a female
patient with risk factors ] . -
pubmed
Negative stress echocardiographic study predicts excellent long - term prognosis in
patients with
erectile dysfunction . -
pubmed
However , there are no data on the role of stress echocardiography in assessing the prognosis of
patients with
erectile dysfunction . -
pubmed
HYPOTHESIS : We sought to determine the prognostic utility of negative stress echocardiography study in
subjects with
erectile dysfunction and compare it to similar subjects without
erectile dysfunction . -
pubmed
There were 28
patients with
erectile dysfunction . -
pubmed
CONCLUSIONS : Our study shows that subjects with
erectile dysfunction who have a negative stress echocardiographic study have a comparable event rate to similar
subjects at high risk for cardiac events on long - term follow - up . -
pubmed
Serological typing of
Proteus strains from
infantile enteritis and other sources . -
pubmed
The present study reports the effects of lesions in the left amygdala on
anxiety , respiration , skin conductance , heart rate , and electrical potentials in the right amygdala in two
patients . -
pubmed
Trait and anticipatory - state
anxiety were measured before and after left amygdala resection to control medically intractable
epilepsy in the
patients . -
pubmed
Lesions in the left amygdala resulted in decreases of trait and state
anxiety , respiratory rate , and activity in the right amygdala in both
patients ; one
patient also showed notable decreases in skin conductance and heart rate . -
pubmed
METHODS : To investigate tubular
toxicity of
CsA , increasing concentrations of
CsA ( 1 , 2.5 , 10 , 25 , 50 and 100 micro g / ml ) and its vehicle (
cremophor ) were added to isolated
rat proximal tubules ( PT ) . -
pubmed
BACKGROUND :
Mycobacterium avium causes
disseminated infection in immunocompromised patients and triggers a process resembling
Crohn ' s disease in
goats . -
pubmed
RESULTS : Donor
ischemia time ( 188 versus 165 minutes ) and cardiopulmonary bypass time ( 127 versus 127 minutes ) were not significantly different for the retransplant
patients . -
pubmed
Of the 80
patients operated for multinodular lesions ,
malignant tumours were found in 29 and benign
tumours in 36
patients ( 81 % ) and
non - tumorous lesions in 15 ( 19 % ) patients . -
pubmed
MATERIAL AND METHODS : This study included thirty
patients following first acute
myocardial infarction and thirty healthy
volunteers . -
pubmed
RESULTS : Except phagocytic index , all phagocytic parameters of monocytes and neutrophils were increased in acute
myocardial infarction patients on admission and on the second day of hospitalization . -
pubmed
On the seventh day after acute event only the mononuclear phagocyte count in fixed volume of peripheral blood showed significant increase in acute
myocardial infarction patients , while percentage of phagocytosis , phagocyte count in fixed volume of peripheral blood and phagocyte capacity of neutrophils were increased during the whole investigated period . -
pubmed
CsA prevents
GCA in a dose - dependent fashion in the
rat allograft . -
pubmed
Plasma kinetics and uptake by the
tumor of a
cholesterol - rich microemulsion ( LDE ) associated to
etoposide oleate in
patients with
ovarian carcinoma . -
pubmed
Here , we determined in
patients the plasma kinetics of LDE -
etoposide oleate and verified whether the complex concentrates in
ovarian carcinomas . -
pubmed
METHODS :
[ ( 3 ) H ]- etoposide oleate associated to LDE labeled with
[ ( 14 ) C ]- cholesteryl oleate was intravenously injected into four ovarian
carcinoma patients ( 50 + /- 8.7 years ) 24 h before surgery . -
pubmed
Recent clinical trials have demonstrated reductions in all - cause mortality in ICD - treated
patients , especially those with severe
left ventricular dysfunction . -
pubmed
The Use of the
Rodent - adapted MEF1 Strain of
Human Poliomyelitis in Neutralization Tests with Serum of Apparently Normal African Natives . -
pubmed
Use of intrathecal
baclofen in a
child with
spastic paraparesis related to
human immunodeficiency virus infection : A case report . -
pubmed
To my knowledge , this is the first reported successful treatment of
spasticity with
ITB in a
patient with stable
HIV infection . -
pubmed
Newer non - pharmacological therapies for
heart failure are being evaluated for
patients of
congestive heart failure (
CHF ) . -
pubmed
Mechanical support with left ventricular assist devices and heart transplantation are reserved for the minority of
patients who have severely decompensated
heart failure . -
pubmed
Despite these therapeutic advances , it is generally accepted that current therapies do not adequately address the clinical need of
patients with
heart failure , and additional strategies are being developed . -
pubmed
It has improved exercise tolerance and NYHA functional class in such
patients in
sinus rhythm and a recent meta - analysis has also shown mortality benefits in
CHF . -
pubmed
On the apical surfaces of ciliated cells of pregnant
rat respiratory epithelium disoriented cilia and cilia with dilated
blebs at their free ends were observed . -
pubmed
The study groups consisted of 76 preterm infants with gestational ages ranging from 28 to 36 weeks , and birthweights ranging from 1046 to 2352 g. Serum FC levels were measured in preterm
infants ( group A , 37 with
RDS ; group B , 39 controls without
RDS ) within the first 6 hours after birth , on days 3 and 7 . -
pubmed
Decreased neonatal serum
carnitine levels in preterm
infants with
RDS during the first week of life might be caused by increasing consumption of
carnitine in lung tissue for surfactant synthesis . -
pubmed
The aim in the management of
patients with
aSAH is not only to prevent rebleedings by treating the
aneurysm by either microneurosurgery or endovascular surgery , but also to evacuate acute space - occupying
hematomas and to treat
hydrocephalus . -
pubmed
METHODS : This review is based on the experience of the authors in the management of more than 7500
patients with
aSAH treated in the Department of Neurosurgery at Helsinki University Central Hospital , Finland . -
pubmed
CONCLUSION : Multidisciplinary and professional teamwork is essential in the management of
patients with
cerebral aneurysms . -
pubmed
Urinalysis before transplantation was only performed in 33
patients ( 22.8 % ) including three ( 2.1 % ) who had
proteinuria . -
pubmed
Device performance and construct validity are examined in in - vitro models simulating the brain , and in
piglets subjected to
hypoxia ,
hypoxia -
ischemia , and hyperoxic conditions using a weighted average of arterial and cerebral venous
O ( 2 ) saturation measured by
CO - oximetry . -
pubmed
METHODS : CBA revealed
chromosomal aberrations in 18
patients suffering from
myelodysplastic syndrome ( n = 13 ) ,
acute myeloid leukemia ( n = 3 ) , or
chronic myeloproliferative syndrome ( n = 2 ) . -
pubmed
This etiological agent of
human trichinellosis shows worldwide distribution in domestic and/or sylvatic animals . -
pubmed
Patients experienced minimal and transient side effects that included puritus ,
erythema and
swelling . -
pubmed
Mean plasma DNA concentrations were significantly increased in
TBI patients ( 366,485 and 131,708 kilogenomes - equivalents / L , at study entry and 24 h later , respectively ) compared with the control group ( 3031 kilogenomes - equivalents / L ) . -
pubmed
The degree of exercise
hypoxemia reflects pulmonary artery pressure during early exercise in
chronic obstructive pulmonary disease patients . -
pubmed
To investigate whether the severity of
exertional hypoxemia , as evaluated by the Deltaartery
oxygen tension /
Deltaoxygen consumption ( PaO(2)-slope ) correlates with the mean pulmonary artery pressure ( Ppa ) , cardiopulmonary exercise testing with haemodynamics was done in 10
patients with moderate to very severe
COPD . -
pubmed
Adult
patients attending a
pain relief unit with a diagnosis of
chronic pain whose
pain was described as moderate or severe were eligible for the study . -
pubmed
The pathogens most frequently isolated in patients with
bacteriuria were
Candida albicans and
Escherichia coli . -
pubmed
The pathogen most frequently isolated in
UTI in
trauma patients was
E. - pubmed
Improving soft - tissue contrast in four - dimensional computed tomography images of
liver cancer patients using a deformable image registration method . -
pubmed
Cushing believed that
tonsillar herniation was a cause of acute cardiorespiratory compromise in
patients with
intracranial tumors . -
pubmed
However ,
lupine provokes
allergic reactions in susceptible individuals . -
pubmed
INTRODUCTION : Strategies that optimize early diagnosis of
chronic kidney disease (
CKD ) are paramount to decrease progression of the disease and the burden of
patients needing renal replacement therapy . -
pubmed
Although extensive studies have demonstrated the symptomatic efficacy of
donepezil treatment in
patients with
AD , the effects of
donepezil , if any , on the
AD process are not known . -
pubmed
In this study , we sought to determine whether long - term administration of
donepezil would slow
amyloid plaque deposition or confer neuronal protection in a
mouse model of
AD . -
pubmed
These
mice exhibited
facial abnormalities and impaired growth , two traits associated to
RSTS in
humans . -
pubmed
[ Comparative evaluation of the
omeprasol and
pantoprasol efficacy in treatment of
gastropathy induced by non -
steroid anti - inflammatory drugs in the
patients with
rheumatoid arthritis ] . -
pubmed
The main criterion for the selection of suitable
patients should be the cranial extent of the
tumor . -
pubmed
HIV as a risk factor for
lung cancer in women : data from the Women 's Interagency HIV Study . -
pubmed
PURPOSE : Prior reports of an increased risk of
lung cancer in HIV - infected individuals have not always included control groups , nor considered other risk factors such as
tobacco exposure . -
pubmed
Metabolic effects of free
fatty acids during
endotoxaemia in a
porcine model -- free
fatty acid inhibition of growth hormone secretion as a potential catabolic feedback mechanism . -
pubmed
The present study was designed to test whether increased levels of
free fatty acids ( i ) inhibit growth hormone secretion and ( ii ) induce
insulin resistance during acute endotoxin exposure in a
porcine model of
critical illness . -
pubmed
We conclude that high levels of free
fatty acids reduce circulating growth hormone concentrations in
porcine endotoxaemia ; this probably constitutes a negative feedback mechanism whereby growth hormone induced - stimulation of
free fatty acids release inhibit growth hormone secretion . -
pubmed
Infection of
man by the virus of contagious
pustular dermatitis of
sheep . -
pubmed
Increases in carcass
leanness were reported for
cattle fed ZH mainly through a reduction in yield grades . -
pubmed
METHODS : Genomic DNA from epithelial oral cells of 37 generalized
AgP patients and 37 controls were purified and modified by
sodium bisulphite . -
pubmed
We present here the case of a paediatric
patient with
TSC in whom
sirolimus has been used successfully to halt growth of
renal AMLs . -
pubmed
Acroangiodermatitis (
synonym pseudo - Kaposi sarcoma ) is an unusual , benign condition which clinically presents as purple - colored patches ,
plaques or nodules , mostly on the extensor surfaces of lower extremities in
patients with
chronic venous insufficiency and
arteriovenous malformations . -
pubmed
Eleven
patients were in
relapse and 8
patients were refractory to their first line of treatment . -
pubmed
Infection of
mice with
murine gammaherpesvirus-68 (
gammaHV-68 ) serves as a model to understand the pathogenesis of persistent
viral infections , including the potential for co -
infections to modulate viral latency . -
pubmed
We have previously found that
infection of neonates ( 8 - day - old
mice ) with gammaHV-68 resulted in a high level of persistence of the virus in the lungs as well as the spleen , in contrast to
infection of adult
mice , for which long - term latency was only readily detected in the spleen . -
pubmed
BACKGROUND & amp ; AIMS :
Recurrence of
chronic hepatitis C and progressive
fibrosis in liver transplants is frequent and impairs both graft and
patient survival . -
pubmed
METHODS : To induce
liver fibrosis ,
rats underwent bile duct ligation and treatment with
sirolimus ( 2mg / kg ) ,
everolimus ( 3mg / kg ) ,
tacrolimus ( 1mg / kg ) , and
cyclosporin A ( 10mg / kg ) daily for 5 weeks . -
pubmed
Relationship between HbA1c and coronary flow rate in
patients with
type 2 diabetes mellitus and angiographically normal coronary arteries . -
pubmed
STUDY DESIGN : The study included 54 consecutive
patients ( 36
males , 18
females ; age range 37 to 72 years ) with
type 2 DM , whose coronary arteries were found normal on coronary angiography . -
pubmed
Thirty - eight
patients ( 70.4 % ) were found to have
SCF in at least one coronary artery . -
pubmed
The mean HbA1c level was significantly higher in
patients with
SCF compared to
patients without
SCF ( 7.8 + -1.9 % vs. 5.6 + -0.9 % ; p<0.001 ) . -
pubmed
Hyperactivity in the amygdala and hypoactivity in the vlPFC have been reported in
manic bipolar patients scanned during the performance of an affective faces task . -
pubmed
Systemic complications occurred in 2 cases ( 0.7 % ) , in the form of
back spasms in one
patient and
pulmonary edema in the other . -
pubmed
A total of 31 % of
patients with the preangiographic diagnosis of
transverse myelitis were found to have a
vascular malformation . -
pubmed
South East Scotland experience of
HIV testing in patients newly diagnosed with
lymphoma . -
pubmed
Temporal associations of early
patient transfers and mortality with the implementation of a regional
myocardial infarction care model . -
pubmed
PURPOSE : In an effort to restore functional form vision , epiretinal prostheses that elicit percepts by directly stimulating remaining retinal circuitry were implanted in
human subjects with advanced
retinitis pigmentosa RP ) . -
pubmed
METHODS : Experiments were performed on a single
subject with severe
RP ( implanted with a 16 - channel epiretinal prosthesis in 2004 ) on nine individual electrodes . -
pubmed
Unlike other
infections of
C. - pubmed
elegans characterized to date , the
infection by
B. - pubmed
anthracis can result in lethal
infection of
C. - pubmed
Our data demonstrate that one potential property of PFPs is to sensitize the host to
bacterial infection and further that
C. - pubmed
Studies on Jurkat / WT
human T -
lymphoblastic leukemia cells showed that incorporation of
paclitaxel in the nanoparticles led to a 4 - fold increase of its
cytotoxicity ( 6.8x10(-6 ) M ) in comparison with
paclitaxel solution . -
pubmed
They are strongly associated with
tobacco and
alcohol consumption , but recent studies showed the presence of
HPV in patients with these types of
cancer . -
pubmed
The incidence of
cancers of the head and neck potentially attributable to
HPV has increased in the last years . -
pubmed
This study aims to provide population - based estimates of the burden of hospitalisation for head & amp ;
neck neoplasm in Spain that may be useful when cost - effectiveness models are developed to evaluate the impact of
HPV vaccination in Spain . -
pubmed
Paraneoplastic neurological syndromes (
PNS ) are
rare nervous system dysfunctions in
cancer patients , which are not due to a local effect of the
tumour or its
metastases . -
pubmed
PNS in
adults are mainly associated with
lung cancer , especially
small cell lung cancer ,
lymphoma and
gynaecological tumours . -
pubmed
Since autoantibodies directed against
tumour and nervous system tissue can be observed , an autoimmune aetiology has been suspected in
PNS patients . -
pubmed
Characterization of
human herpes virus 8 genotypes in
Kaposi ' s sarcoma patients in Tehran , Iran . -
pubmed
Thirty
rabbits underwent
aortic balloon injury and were fed a high - fat diet for 20 weeks . -
pubmed
This requires trials that include thousands of
acute stroke patients . -
pubmed
Gene array in graft - induced C3H / HeJ
mice revealed that genes involved in
retinoic acid (
RA ) synthesis were increased , whereas RA degradation genes were decreased in
AA compared with sham controls . -
pubmed
This was confirmed by immunohistochemistry in biopsies from
patients with
AA and both
mouse and
rat AA models . -
pubmed
RA levels were also increased in C3H / HeJ
mice with
AA . -
pubmed
C3H / HeJ
mice were fed a purified diet containing one of the four levels of dietary
vitamin A or an unpurified diet 2 weeks before grafting and
disease progression followed . -
pubmed
High
vitamin A accelerated
AA , whereas
mice that were not fed
vitamin A had more severe disease by the end of the study . -
pubmed
Fish oil supplementation is beneficial on caloric intake , appetite and mid upper arm muscle circumference in
children with
leukaemia . -
pubmed
A randomised trial was carried out to determine the effect of supplementation of
fish oil among 51
children with
leukaemia aged 4 to 12 years on appetite level , caloric intake ,
body weight and lean body mass . -
pubmed
In conclusion , supplementation of
fish oil has a positive effect on appetite level , caloric intake and MUAMC among
children with
leukaemia . -
pubmed
Protective antibodies play a critical role in an effective
HIV vaccine ; however , eliciting antibodies to block
infection by viruses from diverse genetic subtypes remains a major challenge . -
pubmed
Understanding the cross reactivity and specificities of serum antibody responses that mediate broad neutralization of the virus in
HIV-1 infected Chinese patients will provide valuable information for the design of vaccines to prevent
HIV-1 transmission in China . -
pubmed
To determine the role of striatal dopaminergic innervation on upper limb synergies during walking , we measured arm kinematics in 13
subjects with
Parkinson disease . -
pubmed
Patients with
acute appendicitis who underwent appendectomy were chosen as the control group . -
pubmed
However , 73.7 % of the
patients had
testicular torsion when the diurnal temperature change was 6C or greater . -
pubmed
Autophagy is associated with numerous patho - physiological conditions , and dysregulation of autophagy contributes to the pathogenesis of a variety of
human diseases including
cancer . -
pubmed
A better understanding of biology of autophagy and its implication in
human health and disorder , as well as the relationship between autophagy and apoptosis , has the potential of facilitating the development of autophagy - based therapeutic interventions for
human diseases such as
cancer . -
pubmed
Patients with
Alzheimer ' s disease were compared to a healthy age - matched control group . -
pubmed
RESULTS : A bilateral frontal negativity in combination with deep temporal positivity occurring 500 ms after stimulus offset was reduced in
patients with
Alzheimer ' s disease , but was unaffected by physiological aging . -
pubmed
The present study demonstrated that the TLT powers currently utilized in
animal stroke studies do not cause cortical tissue heating and histopathological damage . -
pubmed
Especially ,
lung cancer is top - ranked in
cancer - associated
human death . -
pubmed
Taken together , these findings suggest that the novel
daphnane diterpenoids might provide lead candidates for the development of therapeutic agents for
human lung cancers . -
pubmed
Hypoglycaemia risk among a hospitalised
stroke patient cohort : a case for increased vigilance in
glucose monitoring . -
pubmed
We conducted a retrospective cohort study involving a review of the records of 112
patients consecutively admitted with
acute stroke or
transient ischaemic attack (
TIA ) to all three district general hospitals in one Health and Social Care Trust in Northern Ireland from 1 January to 15 April 2008 . -
pubmed
We compared interventions and clinical outcome between
patients who experienced
hypoglycaemia (
glucose<4.0 mmol / l ) in the first 5 days , and patients with higher
glucose results . -
pubmed
Two
patients experienced episodes of
hypoglycaemia on 2 or more days . -
pubmed
Six
patients experienced
hypoglycaemia at the lower threshold of
glucose<3.5 mmol / l and this was not associated with a history of
diabetes . -
pubmed
A history of
diabetes mellitus prompted near
patient glucose testing , but among patients without diagnosed
diabetes , glycaemia was under - monitored . -
pubmed
Patients in the first 5 days after
stroke have a small risk of
hypoglycaemia . -
pubmed
There is a need for greater vigilance in the monitoring of
glucose among
patients admitted to hospital with
stroke or
TIA . -
pubmed
METHODS : PPMOs were evaluated in vitro using minimum inhibitory concentration ( MIC ) and viability assays , and in vivo using
murine pulmonary infection models with intranasal
PPMO treatment . -
pubmed
Mice treated with & gt;=0.25 mg / kg of ( RXR)4 - AcpP survived longer and had less
inflammation and bacterial lung burden than
mice treated with a scrambled - sequence
PPMO or
phosphate - buffered saline . -
pubmed
[ Clinically mild
encephalitis /
encephalopathy with a reversible
splenial lesion of corpus callosum in a
child and literature review ] . -
pubmed
METHOD : The clinical and imaging features of one pediatric
patient with the diagnosis of
MERS were analyzed and the clinical and radiologic data of 44
MERS cases which were reported all around the world were also analyzed . -
pubmed
On the second day of the disease course , the
patient presented symptoms of
encephalopathy . -
pubmed
Most of the 44
patients diagnosed with
MERS were associated with
infectious diseases and completely recovered within two weeks . -
pubmed
Donor cell - derived
myelodysplastic syndrome with
ring chromosome 7 after allogeneic hematopoietic stem cell transplant in 2
patients with
lymphomas as primary disease . -
pubmed
INTRODUCTION :
T - condylar fractures of the humerus are very rare in
children . -
pubmed
METHODS : The study encompassed total of 19
patients with
T - condylar fracture , aged from 3 to 16 years , who underwent either closed or opened reduction between February 2005 and September 2012 . -
pubmed
According to the type of
fracture , excellent results were achieved in 10 , good in 8 and poor in one
patient . -
pubmed
RESULTS : Eighty ( 57 % )
patients were identified as having
THAA . -
pubmed
There were three surgical reinterventions ( PAA in 2
patients and distal aortic arch in 1
patient ) and nine catheter reinterventions ( all related to
anastomotic stenosis ) during a median follow - up period of 18 months . -
pubmed
CONCLUSIONS : The hypoplastic PAA segment in
patients with
CoA /
THAA grew significantly after EEEA but remained smaller than in those without
THAA . -
pubmed
Contrast Free Duplex - Assisted EVAR in
Patients with
Chronic Renal Insufficiency . -
pubmed
This report describes three cases of duplex - assisted EVAR in
patients with
chronic renal insufficiency . -
pubmed
Anti -
Saccharomyces cerevisiae antibody titres correlate well with disease activity in
children with
Crohn ' s disease . -
pubmed
Of 28
children with
RSE , eleven ( 39 % ) were treated with a
pentobarbital infusion after failure to control
RSE with a
benzodiazepine infusion ; while17
children ( 61 % ) required only a
benzodiazepine infusion . -
pubmed
Children requiring
pentobarbital therapy were more likely to develop
hypotension , require inotropic support , need intubation , mechanical ventilation , peripheral nutrition , and blood products ; furthermore , they were more likely to develop
hypertension and
movement disorder after or during weaning . -
pubmed
In conclusion ,
children with
RSE who required
pentobarbital therapy had a longer hospital stay with more complications . -
pubmed
Respiratory syncytial virus (
RSV ) is a leading cause of lower
respiratory tract infections in children . -
pubmed
CONCLUSIONS : Despite the effectiveness of the treatment with topical 3 %
diclofenac in 2.5 % HA , the
patients who achieve the complete clinical response should be adequately educated to continue their photoprotection in order to minimize
recurrence of
AK . -
pubmed
Robust effects of genetic background on responses to
subarachnoid hemorrhage in
mice . -
pubmed
Outcome varies among
patients with
subarachnoid hemorrhage but known prognostic factors explain only a small portion of the variation in outcome . -
pubmed
We hypothesized that individual genetic variations influence brain and vascular responses to
subarachnoid hemorrhage and investigated this using inbred
strains of
mice . -
pubmed
Subarachnoid hemorrhage was induced in seven inbred and a chromosome 7 substitution
strain of
mouse . -
pubmed
After 48 h of
subarachnoid hemorrhage ,
mice showed significant
middle cerebral artery vasospasm that correlated positively with reduction in cerebral blood flow at 45 min . -
pubmed
Mice also had increased
neuronal injury compared to sham controls ; A / J and C57BL/6 J strains represented the most and least severe , respectively . -
pubmed
Our data suggested that
mouse genetic background influences outcome of
subarachnoid hemorrhage . -
pubmed
These findings also have implications for
animal modeling of disease and suggest that genetic differences may also modulate outcome in other
cardiovascular diseases . -
pubmed
METHODS : Fifty - eight
patients affected with
RA ,
AS and
PsA were prospectively enrolled . -
pubmed
Currently ,
pemetrexed (
PMX)-based chemotherapy is the mainstay of chemotherapy for
MPM , however , the outcome of
PMX - based chemotherapy in
patients with
MPM is dismal . -
pubmed
METHODS : This cross - sectional study investigated 68
children and adolescents with
IBD ( 57
Crohn disease , 11
ulcerative colitis ) . -
pubmed
Hypothalamic paraventricular nucleus stimulation reduces
intestinal injury in
rats with
ulcerative colitis . -
pubmed
CONCLUSION : Chemical stimulation of the hypothalamic PVN provides a protective effect against
UC injury in
rats . -
pubmed
The versatility and functionality of this system was successfully validated in several lactobacilli species ; furthermore , we assessed in vivo LIVE system in two different
mouse models of
human pathologies : ( i ) a model of therapy against
intestinal inflammation (
inflammatory bowel diseases ) and ( ii ) a model of vaccination against
dental caries . -
pubmed
In addition , the significant antibacterial efficacy and antibiofilm activity of biopolymer capped AgNPs were demonstrated against different bacterial
strains ,
Staphylococcus aureus MTCC 740 and
Escherichia coli MTCC 9492 . -
pubmed
Although adjuvant chemoradiotherapy has been an important part in the treatment of
gastric cancer , whether or not adjuvant radiation can benefit
patients undergoing resection with D2 lymph node dissection remains controversial . -
pubmed
A total of 337
patients with resected
gastric cancer treated at Zhongnan Hospital of Wuhan University from 2004 to 2012 were retrospectively analyzed . -
pubmed
Patients completed the neck disability index ( NDI ) , short - form 12 ( SF-12 ) and visual analog
pain scale ( VAS ) before surgery , then at 3 , 6 , 12 , and 24 months after surgery . -
pubmed
The acute hemodynamic response to
captopril ( 8
patients ) and
enalapril ( 8
patients ) was evaluated in
congestive heart failure patients in NYHA functional class III . -
pubmed
All
patients had a history of
congestive heart failure for more than six months . -
pubmed
One
patient in the
captopril group deteriorated and underwent a successful heart transplantation and one
patient in the
enalapril group returned with
arrhytmias and
hypertension ( probably not drug - related ) after 48 h of therapy . -
pubmed
CONCLUSION :
Dermoid tumors should be considered among the differential diagnosis of
intradural lesions in young
patients even without any other
congenital abnormality . -
pubmed
This multicenter , double - blind , randomized , parallel - group , non - inferiority study compared the efficacy and safety of
morinidazole with those of
ornidazole in
women with
pelvic inflammatory disease . -
pubmed
For
women with
pelvic inflammatory disease , twice - daily
morinidazole for 14 days was clinically and bacteriologically as efficacious as twice - daily
ornidazole for 14 days , while the former was associated with fewer drug - related adverse events than the latter . -
pubmed
Vitamin D levels are commonly lower in
patients with
GH deficiency (
GHD ) than in controls , with a variable prevalence of insufficiency or deficiency , and this condition may worsen the already known cardiovascular and metabolic risk of
GHD , although this finding is not common to all studies . -
pubmed
We enrolled 110
patients with advanced
NPC . -
pubmed
A 39 year - old
woman with
malignant foot melanoma underwent wide excision of the primary
tumor with a safety margin and sentinel lymph node biopsy ( SLNB ) for the right inguinal lymph node . -
pubmed
Patients with increased
craniofacial injuries have an increased risk for airway complications and need for tracheostomy . -
pubmed
Short- and long - term outcomes of laparoscopic radical hysterectomy for obese
patients with
cervical cancer . -
pubmed
PURPOSE : To perform a preliminary comparison of the short- and long - term outcomes of laparoscopic hysterectomy ( LH ) between obese and non - obese
patients with
cervical cancer . -
pubmed
METHODS : A total of 243 cases of
cervical cancer patients were treated with LH between April 2009 and January 2016 . -
pubmed
Based on their
body mass index (
BMI ) at the time of surgery ,
patients were divided into an
obese group ( BMI & gt;= 25 kg / m2 ) and a non - obese group (
BMI & lt ; 25 kg / m2 ) . -
pubmed
RESULTS : Sixty - four
patients were classified as
obese and 179 as non - obese . -
pubmed
The proportion of
patients with
type-2 diabetes mellitus ( p=0.006 ) ,
hypertension ( p=0.021 ) , and
hyperlipidemia ( p=0.008 ) in the obese group was significantly higher than that in the non - obese group . -
pubmed
Compared with the non - obese group , the
obese patients had longer operative time ( p=0.039 ) , more intraoperative
blood loss ( p=0.025 ) , and a higher rate of conversion ( p=0.025 ) . -
pubmed
METHODS : Three
patients with
giant condylar osteoma were enrolled in this study . -
pubmed
Pain relief of the joint and mouth - opening improvement were significant in 3
patients . -
pubmed
Cryptococcus neoformans is a common environmental yeast and opportunistic pathogen responsible for 15 % of
AIDS - related deaths worldwide . -
pubmed
Dose - dependent
acute phase response of aqueous leaf decoction of
Nerium oleander in
Wistar rats . -
pubmed
Identification of prognostic factors for activities of daily living in elderly
patients after hospitalization for acute
infectious disease in Japan : A 6 - month follow - up study . -
pubmed
METHODS : The present prospective cohort study included 131
patients who were hospitalized due to acute
infectious disease and who had undergone rehabilitation during hospitalization . -
pubmed
Temporal Stability of Rotors and Atrial Activation Patterns in Persistent
Human Atrial Fibrillation : A High - Density Epicardial Mapping Study of Prolonged Recordings . -
pubmed
BACKGROUND : The prevalence , stability , and mechanistic importance of rotors in
human atrial fibrillation (
AF ) remain unclear . -
pubmed
CONCLUSIONS : In
patients with longstanding , persistent
AF , activation patterns are spatiotemporally stable over 10 min . -
pubmed
We aimed to evaluate all types of
patients with
FH using the potentially more sensitive speckle tracking echocardiography ( STE ) technique to identify early
left ventricular ( LV ) dysfunction . -
pubmed
Nine homozygote , two compound heterozygote , and 82 heterozygote
FH patients and 85 healthy subjects were prospectively studied . -
pubmed
Our study found that cardiac functions of homozygote
patients who had the
highest cholesterol levels were disrupted at very early ages . -
pubmed
Correction to : Effect of a short - term dietary supplementation with
phytosterols ,
red yeast rice or both on lipid pattern in moderately
hypercholesterolemic subjects : a three - arm , double - blind , randomized clinical trial . -
pubmed
Safety and efficacy of Nab -
paclitaxel plus
gemcitabine in
patients with advanced
pancreatic cancer suffering from
cholestatic hyperbilirubinaemia - A retrospective analysis . -
pubmed
INTRODUCTION : Treatment of
patients with advanced
pancreatic carcinoma (
APC ) and
hyperbilirubinaemia is problematic because these
patients were regularly excluded from clinical studies . -
pubmed
This retrospective study investigated the safety and efficacy of nab - P / G in
patients with
APC and
cholestatic hyperbilirubinaemia . -
pubmed
METHODS : We screened our prospective database for
patients with
APC treated with nab - P / G at total
bilirubin levels of & gt;=1.2 mg / dl . -
pubmed
Patients were risk stratified according to the
CMML - specific Prognostic Scoring System ( CPSS ) and the MD Anderson Prognostic Scoring System . -
pubmed
MP - CMML
patients had significantly shorter overall survival ( OS ; P & lt ; .0001 ; hazard ratio : 0.53 , 95 % confidence interval : 0.42 - 0.65 ) and median duration to
acute myeloid leukemia (
AML ) transformation ( P & lt ; .0001 ; 15.2 vs 22.0 months ) compared with
MDS -
CMML patients . -
pubmed
Forty - three percent of
patients developed
radiation retinopathy , and 20 % developed
optic neuropathy ; 39 % lost & gt;=6 Snellen lines of vision . -
pubmed
BACKGROUND : The topic of whether preoperative Th1 / Th2 cells and their related factors have a predictive value for postoperative
febrile urinary tract infection (
UTI ) in
patients with
ureteral calculi has not been explored . -
pubmed
MATERIAL AND METHODS : One hundred sixty
patients who underwent ureteroscopic pneumatic lithotripsy in the Affiliated Hospital of Hangzhou Normal University ( China ) were recruited and divided into febrile
UTI group ( n = 78 ) and non -
UTI group ( n = 82 ) . -
pubmed
CONCLUSIONS : Perioperative Th2 dominance was correlated with the risk of postoperative febrile
UTI after ureterscopy in
patients with
ureteral calculi , which can provide clinical guidance for the development of individualized treatment . -
pubmed
CONCLUSION : Once - weekly
semaglutide was considered highly cost - effective versus
liraglutide 1.2 mg for the treatment of
patients with
type 2 diabetes in Estonia . -
pubmed
In the second
patient suffering from
hepatic cirrhosis and hospitalized because of
esophagogastric bleeding the deforming posterior ventricle wall lump was discovered during the laparotomy and stomach operating exploration . -
pubmed
Impact of immunohistochemistry on the diagnosis and management of
primary aldosteronism : An important tool for improved
patient follow - up . -
pubmed
Most
patients with
aldosterone - producing
adenoma are biochemically cured by unilateral adrenalectomy , but
patients with
bilateral hyperplasia have a significant risk of residual or recurrent disease . -
pubmed
MATERIALS AND METHODS : : A total of 39
patients with
primary aldosteronism who underwent unilateral adrenalectomy for a presumed
adenoma during 2013 - 2016 were included . -
pubmed
RESULTS : : In all , 22
patients had an
aldosterone - producing
adenoma , while 13
patients were judged to have
hyperplasia . -
pubmed
This procedure should be part of the histopathological routine in all operated primary
aldosteronism patients . -
pubmed
During an annual
corn disease survey in mid - September 2001 , sporadic symptoms typical of gray leaf
spot ( causal agent
Cercospora zeae - maydis Tehon & amp ; E.Y. -
pubmed
We have suspected that gray leaf
spot has been present in Ontario for a few years based on unconfirmed reports from the seed
corn industry , but to our knowledge , this is the first confirmed report of this pathogen in Canada . -
pubmed
After 1 , 3 , and 6 months operation , the
animals were sacrificed , and the repair outcomes of
chondral defects were evaluated using Magnetic Resonance Imaging ( MRI ) , macro- and microscopic observation , and histological analysis . -
pubmed
Thus , we provide a robust method to reproducibly generate 3D
human midbrain organoids containing mDANs to investigate
PD - relevant patho - mechanisms . -
pubmed
AIMS :
Patients undergoing coronary artery bypass grafting ( CABG ) surgery may experience
neurological impairment . -
pubmed
Impact of contrast ultrasound diagnosis for
patients with
liver cancer . -
pubmed
Introduction : Soft - robotic gloves have been developed to enhance grip to support
stroke patients during daily life tasks . -
pubmed
Conclusions : Based on these promising results , further research will be done to investigate the possibility to use classification of the movements in
stroke patients . -
pubmed
In this study , we evaluated 118
patients with
Parkinson ' s disease matched for age , sex and education with 35 healthy control subjects . -
pubmed
Patients with
Parkinson ' s disease were classified with normal cognition ( n = 52 ) ,
mild cognitive impairment ( n = 46 ) , and
dementia ( n = 20 ) based on an extensive neuropsychological evaluation . -
pubmed
Four out of 23 ( 17 % )
patients developed Grade 3
skin toxicity . -
pubmed
Conclusions : For
patients not eligible for surgery , radiation therapy is an option with a moderate chance of complete response ( 65 % ) and a 17 % risk of poor
wound healing / radiation
necrosis . -
pubmed
In this study , we recruited 26 long - term institutionalized
schizophrenia patients , 27 community - dwelling
schizophrenia patients , and 27 healthy controls . -
pubmed
In this study , we utilized a
human neural stem cell ( hNSC)-based system to evaluate the potential developmental
neurotoxic effects of the above - mentioned five chemicals , at environment and
human exposure relevant concentrations . -
pubmed
We previously reported that dietary
Glu - Cer from
rice bran had inhibitory effects on
human head and neck squamous cell carcinoma (
HNSCC ) in
nonobese diabetes ( NOD )/ severe combined immunodeficiency ( SCID ) mice . -
pubmed
The purpose of the present study was to determine whether dietary
Glu - Cer had anticarcinogenic and antitumorigenic effects in a
mouse model of
HNSCC . -
pubmed
RESULTS : Compared with the
Glu - Cer group
mice , control group
mice more frequently developed individual and multiple
tumors of each type , including
CIS and
SCC , in the mouth , pharynx , or esophagus . -
pubmed
CONCLUSION :
Tumor development was effectively inhibited by dietary
Glu - Cer derived from
rice bran , indicating that this and related compounds show promise as prophylactic agents for
human HNSCC . -
pubmed
Nematode - Associated Bacteria : Production of Antimicrobial Agent as a Presumptive Nominee for Curing
Endodontic Infections Caused by
Enterococcus faecalis . -
pubmed
Deep partial - thickness
burn wounds were created on the back of Bama
pigs . -
pubmed
Minimally invasive surgery in elderly
patients with rectal
cancer : An analysis of the Bi - National
Colorectal Cancer Audit ( BCCA ) . -
pubmed
Elderly
patients had more
postoperative complications ( p < 0.0001 ) and had a longer length of hospital stay ( LOS ; median 11 vs. 8 days for both other groups ; p < 0.0001 ) . -
pubmed
CONCLUSIONS : MIS is performed in just over half of elderly
rectal cancer patients who are selected for elective rectal resection surgery in ANZ . -
pubmed
We developed a multi - functional nanocomposite hydrogel that exhibited antibacterial and angiogenic properties , adhesiveness , and mechanical properties that enhance the regeneration of
bacteria - infected
wounds . -
pubmed
Angiokeratomas and treatment with enzyme replacement therapy in a
patient with
Fabry disease . -
pubmed
Although it is well established that enzyme replacement therapy ( ERT ) prevents or slows the progression of disease on target organs in the majority of
patients , the long - term effect of ERT on
angiokeratomas remains unknown . -
pubmed
We present a
patient diagnosed with
Fabry disease at age 11 , with rapid progression of new
angiokeratomas in typical regions before beginning treatment with ERT . -
pubmed
Basaloid squamous cell carcinoma is commonly observed in the oropharyngeal and anogenital regions and is associated with high - risk
human papillomavirus . -
pubmed
Histopathologic investigations of high - risk
cutaneous squamous cell carcinoma do not routinely involve
human papillomavirus testing . -
pubmed
Since the
patient presented with an aggressive variant of
squamous cell carcinoma and distal
metastasis despite standard therapies ,
human papillomavirus testing was performed . -
pubmed
This is a unique report of
HPV16 in primary
cutaneous basaloid squamous cell carcinoma with distal brain metastasis . -
pubmed
Black soybean has many beneficial physiological activities , and its prevention effects on
CVD risk were reported mainly in animal experiments . -
pubmed
Transcatheter aortic valve replacement ( TAVR ) offers a safe and effective therapy for high - risk
patients suffering from
aortic valve stenosis . -
pubmed
We present a case of a 15 - year - old
patient , diagnosed 4 years before with severe
idiopathic pulmonary hypertension , confirmed by catheterism , with continuous follow up . -
pubmed
METHODS : The
patients with acute
lower limb ischemia who underwent percutaneous mechanical thrombectomy between August 2016 and February 2018 were retrospectively reviewed . -
pubmed
Recanalization of the
thromboembolic occlusions were achieved in all
patients . -
pubmed
Complete
thrombus removal was achieved in all
patients . -
pubmed
White - nose syndrome (
WNS ) is an emerging disease of hibernating bats caused by an environmentally persistent fungus ,
Pseudogymnoascus destructans . -
pubmed
Orbital Swelling in a
Child With
Retinoblastoma Following Intra - arterial Chemotherapy . -
pubmed
This study was conducted to evaluate the effect of high - dose
VitD administration in
patients with
VitD insufficiency on the incidence of
postoperative AKI , the urinary level of tubular biomarkers , and serum anti - inflammatory biomarker after coronary artery bypass graft . -
pubmed
The
patients with
AKI had more
postoperative bleeding and received more blood transfusion . -
pubmed
This study was designed to investigate the sensitivity of
SARS - CoV-2 to different temperatures , to provide basic data and a scientific basis for the control of
COVID-19 epidemic . -
pubmed
METHODS : We included papers comparing
melatonin levels between healthy controls and
human patients belonging to the
AD continuum . -
pubmed
Literature was not conclusive regarding alterations in blood daytime
melatonin levels or regarding saliva
melatonin in
AD patients . -
pubmed
Decreased total and night - time
melatonin production has been described in urine of
AD patients . -
pubmed
The most common clinical finding in five
patients who died after deliberately taking
overdoses of
disopyramide was an early
loss of consciousness after an
apnoeic episode . -
pubmed
An initial response to resuscitation and antiarrhythmic drugs in four
patients was not sustained and these
patients deteriorated rapidly with
cardiac arrhythmias and
loss of spontaneous respiration . -
pubmed
Sera from convalescent
cholera patients possessed toxin - neutralizing antibody as well as passive hemagglutination and radioimmunoassay antibody against both A and B subunits . -
pubmed
[
Haemolysis of white
rat erythrocytes by pathogenic and saprophytic
strains of leptospires ( author 's transl ) ] . -
pubmed
Effects of low and high frequency noise bands in producing a physiologic correlate of
loudness recruitment in
mice . -
pubmed
The effects of
hyperketonemia on
glutamate and
glutamine metabolism in developing
rat brain . -
pubmed
The immunofluorescent staining properties of 65 serum samples from 54
patients with
multiple sclerosis (
MS ) , 63 samples from 55
patients with other
neurological diseases (
OND ) , and sera from 14 healthy normal
individuals were examined on frozen sections of
bovine and
human brain . -
pubmed
When tested on
bovine brain sections , positive oligodendrocyte staining was present in 63 % of
MS sera , 43 % of
OND sera , and 29 % of normal sera . -
pubmed
[ Intravenous
leucine load in
patients with
cirrhosis of the liver ( author 's transl ) ] . -
pubmed
In 6
patients with
cirrhosis of the liver and in 6 healthy controls the elimination half life of the serum
leucine level ( t 1/2 Leu ) was determined after intravenous administration of 50 mg
leucine per kg bodyweight . -
pubmed
It is concluded for
human erythrocytes that 1 ) the increased permeability of the membrane to
calcium produced by
hypertonicity is a time - dependent , reversible phenomenon and is independent of
calcium , 2 ) the increase in intracellular
potassium concentration associated with hypertonic exposure is an important factor contributing to this response , and 3 ) interactions between
calcium and components of the
sodium -
potassium transport system may account for the enhanced uptake of
calcium produced by
hypertonicity . -
pubmed
Failure to produce
warts on
human skin grafts on ' nude '
mice . -
pubmed
Comparative activity of various compounds against clinical
strains of
herpes simplex virus . -
pubmed
Disturbances of neurovascular function in the extremities may occur in
patients with
diabetes mellitus , exposure to toxic substances and chronic exposure to vibrating hand tools , as well as in
Raynaud ' s phenomena . -
pubmed
All subjects were consenting
volunteers without exposure to known
neurotoxic chemicals . -
pubmed
There was a significant reduction ( P & lt ; 0.05 ) in the neurovascular responses of both
diabetics and vibration -- exposed
subjects to
acetylcholine and , in the case of vibration - exposed subjects , to
pilocarpine , but
nitroprusside responses were not significantly different . -
pubmed
Our findings of reductions in neurovascular responses in
diabetics and in
subjects exposed to higher frequency vibration is consistent with recent epidemiological findings . -
pubmed
Human African
trypanosomiasis : presence of antibodies to
galactocerebrosides . -
pubmed
Steady - state pharmacokinetics of
hydroxychloroquine in
rheumatoid arthritis patients . -
pubmed
Steady - state pharmacokinetics of
hydroxychloroquine ( HC )
sulfate (
Plaquenil ) were studied in five
volunteers with
rheumatoid arthritis who had taken 6 mg / kg / d of the drug for at least six months . -
pubmed
30
patients with a
hypertensive intracerebral hematoma were treated by stereotactic evacuation between 1986 and 1988 . -
pubmed
In 19
patients the
hematoma was found in the internal capsule , in 5 in the cerebellum , in 4 in the subcortex , and in 2 in the brain stem . -
pubmed
More than 80 % of the
hematoma could be aspirated in 20
patients and 60 - 80 % in 10 . -
pubmed
One hundred and twenty - three specimens ( 83 primary and 40 metastatic ) of
colorectal cancers from 102
patients were subjected to the
human tumor clonogenic assay ( HTCA ) to determine the clonogenicities of
tumor specimens stratified by the degree of histological differentiation and of
tumor progression . -
pubmed
Infection due to
Pseudomonas aeruginosa persisted or recurred in three patients with
chronic osteomyelitis ; in two of them , the
strain become resistant to
ciprofloxacin , and in the third patient , the results of cultures persisted positive along the whole course , thus , the eradication of the microorganism was not achieved . -
pubmed
Declining platelet counts and
platelet aggregation during
porcine VIII : C infusions . -
pubmed
In this study Aspergillus species ( niger and
fumigatus ) have been the most common
fungal pathogens . -
pubmed
In order to help clarify the clinical importance of
chronic erosive gastritis , we describe our experience of 28
patients with this disorder who were seen over a 2 - yr period . -
pubmed
Three
patients presented with painless
vomiting . -
pubmed
Symptoms in
patients with
chronic erosive gastritis appear to be due to the
gastritis itself rather than to associated lesions . -
pubmed
The risk of
cancer to
humans exposed to soil treated with wastewater / sewage treatment plant sludge , known to be contaminated with small amounts of
polychlorinated dibenzodioxins and
dibenzofurans (
PCDDs and
PCDFs ) , was evaluated . -
pubmed
Blood pressure response to oral
calcium in
persons with mild to moderate
hypertension . -
pubmed
The blood pressure response of 48
hypertensive persons and 32 normotensive
persons to elemental
calcium ( as the
carbonate or
citrate salt ) , 1000 mg / d for 8 weeks , was assessed in a randomized , double - blind , placebo - controlled , crossover trial . -
pubmed
Compared with placebo ,
Ca2 + significantly lowered supine
systolic blood pressure by 3.8 mm Hg , standing
systolic blood pressure by 5.6 mm Hg ( p less than 0.02 ) , and supine
diastolic blood pressure by 2.3 mm Hg ( p less than 0.05 ) in
hypertensive persons . -
pubmed
The response in normotensive
persons differed significantly from that in
hypertensives ( p less than 0.03 ) as their blood pressure was unchanged . -
pubmed
Twenty - one ( 44 % )
hypertensive and 6 ( 19 % ) normotensive
persons achieved a reduction in standing
systolic arterial pressure of 10 mm Hg or greater . -
pubmed
Treatment with 1000 mg / d of oral
Ca2 + for 8 weeks represents a safe , well - tolerated , nonpharmacologic intervention that lowers blood pressure in selected
patients with mild to moderate
hypertension . -
pubmed
Twenty
patients sustaining out - of - hospital
cardiopulmonary arrests and basic cardiac life support were instrumented with thoracic aortic and right atrial catheters on arrival in the emergency department . -
pubmed
Three
patients had systolic Ao - RA gradients of more than 25 mm Hg , which is consistent with some
cardiac compression as a mechanism of flow . -
pubmed
In 11 adult
patients with isolated
valvular aortic stenosis , the progression of the disease was assessed by two heart catheterisations without intervening aortic valve surgery . -
pubmed
Four
patients had bicuspid valves , whereas the remaining seven were considered to have acquired
aortic stenosis . -
pubmed
[ Comparison of the clinical course and secretory activity of the stomach in smoking and non - smoking
patients with
peptic ulcer ] . -
pubmed
Influence of
toyocamycin on
avian leukemia myeloblasts : cell growth , ultrastructure , RNA synthesis , and elaboration of
BAI strain A virus . -
pubmed
Cigarette smoking and
cholesterol atherosclerosis of
rabbits . -
pubmed
Observations on the histogenesis of the
inner ear degeneration of the deaf white
cat and its possible relationship to the aetiology of certain unexplained varieties of
human congenital deafness . -
pubmed
A number of arboviruses have been associated with
congenital defects in domestic aminals and
man . -
pubmed
In
dog saphenous vein bileaflet valves , there was a large primary spiral vortex as well as a smaller secondary vortex , the latter acting as a trap and generator of
thrombi . -
pubmed
Transfer of delayed
hypersensitivity induced by
Schistosoma japonicum adult worm antigen in
guinea pigs . -
pubmed
Increased systemic vascular responsiveness to
catecholamines in spontaneously
hypertensive rats . -
pubmed
bolus injections of
norepinephrine and
tyramine was evaluated in adult male spontaneously
hypertensive rats ( SHR ) and normotensive
Wistar - Kyoto rats ( WKY ) . -
pubmed
Left ventricular function in
patients with
chronic obstructive pulmonary disease . -
pubmed
We assessed the left ventricle function in 24
patients with severe ( forced expiratory volume in 1 sec less than 50 % of predicted )
chronic obstructive pulmonary disease (
COPD ) and in 21 normal people . -
pubmed
In 13 of the 24
patients with
COPD the mean pulmonary artery pressure and pulmonary artery wedge pressure were recorded . -
pubmed
The
STI in the
patients with
COPD were found abnormal while the echocardiographic parameters and pulmonary wedge pressure were normal . -
pubmed
The effect of quiet conversation on the blood pressure of
hypertensive patients . -
pubmed
Seventy - five
women with aortoiliac (
A - I ) occlusive disease requiring vascular reconstruction during the past 4 years were reviewed . -
pubmed
Women presented with elevated
triglyceride levels as opposed to increased
cholesterol , with frequent
type IV hyperlipoproteinemia . -
pubmed
[ Russian preparations for the metabolic therapy of
multiple sclerosis patients ] . -
pubmed
The
patient with
type II , or non - insulin - dependent , diabetes mellitus (
NIDDM ) is characterized by
obesity and
insulin resistance , with resultant
hyperinsulinemia and
hyperglycemia . -
pubmed
With
sulfonylureas and
metformin , therapy for the
patient with
NIDDM can be more effectively tailored . -
pubmed
Valproate in the treatment of behavioral
agitation in elderly
patients with
dementia . -
pubmed
Ten nursing home
patients ages 71 to 94 years with
dementia and
behavioral agitation were treated prospectively with open - label
valproate at doses of 375 to 750 mg / day over periods of time ranging from 4 to 34 weeks . -
pubmed
Eight ( 80 % ) of the 10
patients showed a 50 % or greater reduction in the frequency of episodes of
behavioral agitation . -
pubmed
The authors conclude that
valproate may be an effective , well tolerated , and safe treatment for behavioral
agitation in elderly
patients with
dementia . -
pubmed
Combination chemotherapy appears to extend the time window for
acute stroke therapy in
rats to 1 h and to result in fewer side effects . -
pubmed
Liver transplantation in
patients with preexisting
malignancy . -
pubmed
In 1991 , a total of 1,829 MTAs were recorded in Muhimbili Medical Centre and these claimed 113
human lives on the
spot and impaired 2,834 who had to attend medical services for
injuries . -
pubmed
Subjective
patient satisfaction recorded 47 ( 94 % ) good to excellent results , with an average
pain relief grade of 87 % . -
pubmed
Between January 1962 and December 1991 , 179
children less than 1 year of age underwent repair of
coarctation of the aorta . -
pubmed
[ Generalized
idiopathic epilepsy in older
children and
adolescents ] . -
pubmed
A
patient presented with a history of chronic
corneal ulceration and
corneal hypoaesthesia . -
pubmed
We treated 70
patients with
acute promyelocytic leukemia (
APL ) with daily oral 45 mg / m2
all - trans retinoic acid (
ATRA ) in 2 multi - institutional prospective studies . -
pubmed
Of 63 evaluable
patients , 21 were resistant to initial induction chemotherapy , 10 were resistant to salvage chemotherapy after
relapse , 17 were in the first
relapse , 4 in the second
relapse , 4 in the third
relapse , and 7 were previously untreated . -
pubmed
This review identified 300
patients who experienced in - hospital
cardiopulmonary arrest during the study period . -
pubmed
[ Anterior chamber dimensions in
patients with angle - closure
glaucoma measured by an anterior eye segment analysis system ] . -
pubmed
The corneal curvatures , iridocorneal angles , anterior chamber depths , and anterior chamber volumes in 26 ( 5 male and 21 female )
patients with primary angle - closure
glaucoma were measured using an anterior eye segment analysis system ( EAS-1000 , Nidek ) . -
pubmed
These findings may help elaborate neuronal models of feeding control and perhaps facilitate progress in the pharmacotherapy of
human obesity and
eating disorders . -
pubmed
The drug is embryotoxic in
rodents and has been reported to produce
neural tube defects in approximated 1 % of prenatally exposed
human offspring . -
pubmed
The present study was designed to determine the
embryotoxicity of
CBZ and its
epoxide intermediate (
CBZ - E ) in a
rodent whole embryo culture system . -
pubmed
The parent compound was
embryotoxic to
mouse embryos at concentrations as low as 12 micrograms , but it was only embryotoxic at 60 micrograms / ml to
rat embryos . -
pubmed
A double - blind comparison of
fluvoxamine and
paroxetine in the treatment of
depressed outpatients . -
pubmed
BACKGROUND :
Fluvoxamine and
paroxetine , both
serotonin selective reuptake inhibitors ( SSRIs ) , were compared at two centers in a 7 - week double - blind study in
outpatients with
major depression , diagnosed by DSM - III - R criteria . -
pubmed
The most common events were
headache ( N = 17 , 57 % ) ,
nausea ( N = 14 , 47 % ) ,
sweating ( N = 10 , 33 % ) ,
somnolence ( N = 9 , 30 % ) ,
diarrhea ( N = 9 , 30 % ) ,
dry mouth ( N = 8 , 27 % ) ,
dizziness ( N = 8 , 27 % ) , and , among
males ,
impotence ( N = 3 , 21 % ) and
ejaculatory abnormality ( N = 3 , 21 % ) in the
paroxetine group , and
headache ( N = 12 , 40 % ) ,
somnolence ( N = 12 , 40 % ) ,
nausea ( N = 11 , 37 % ) ,
dry mouth ( N = 11 , 37 % ) ,
insomnia ( N = 9 , 30 % ) ,
asthenia ( N = 7 , 23 % ) , and
dyspepsia ( N = 7 , 23 % ) in the
fluvoxamine group . -
pubmed
However , there were no independent specific risk significant factors for viridans
streptococcal bacteraemia and
bacteraemia due to Enterobacteriaceae or
Ps . - pubmed
We also did not observe any association between prior therapy with
imipenem and
Stenotrophomonas maltophilia bacteraemias . -
pubmed
However , the mortality of
fungaemia was statistically no different from that of
Ps . - pubmed
HIV and
pneumococcal infection in Africa . -
pubmed
By the 1930s several studies had shown that
Streptococcus pneumoniae was an important pathogen in Nairobi ( Kenya ) and various risk factors for
infection were recognized , including seasonally cold conditions , overcrowding and recent arrival in the city . -
pubmed
One study showed
HIV seropositivity to confer a relative risk of 17.8 for
pneumococcal infection . -
pubmed
HIV - seropositive patients were more prone to
infection with
penicillin- and
tetracycline - resistant organisms than seronegative patients (
penicillin , 27 % vs. 7 % ;
tetracycline , 40 % vs. 17 % ) , a difference reflected by different serotype profiles in the 2 groups . -
pubmed
[ Effect of
osthol and total
coumarins of
fructus cnidii on thyroid hormone and thyrotropic hormone in
kidney - yang deficiency rats ] . -
pubmed
It was suggested that the
osthol and total
coumarins of
Fructus Cnidii could elevate the pituitary - thyroid axis function of
Kidney - Yang Deficiency rats . -
pubmed
One
patient with VATS debridement subsequently required thoracotomy and lobectomy for
lung abscess . -
pubmed
Assessment of the
patients ' mood , general behavior , cognitive functions ( MMSE ) , orientation and
confusion ( OBS ) was made at baseline , and after 6 and 12 months of intervention . -
pubmed
Significant deteriorations for the
patients in CW were seen during the study period as regards the factor strength , functional performance and orientation in the ward , and speech performance and
psychomotor slowing . -
pubmed
Application of nucleus pulposus to the nerve root simultaneously reduces blood flow in dorsal root
ganglion and corresponding hindpaw in the
rat . -
pubmed
Edema was the principal pathologic finding seen consistently in the nerve roots and in many of the associated dorsal root ganglia from nucleus pulposus - treated
animals . -
pubmed
Administration of the PG synthesis inhibitor ,
indomethacin , to wild - type
mice during the fibrogenic phase
postbleomycin worsened the severity of
fibrosis , implying a causal role for
PGE2 deficiency in the evolution of the
fibrotic lesion . -
pubmed
We report our management of a
neurofibroma of the right auriculotemporal nerve in a 46 - year - old
women . -
pubmed
Hepatocarcinogenesis inhibition by
caffeine in ACI
rats treated with
2 - acetylaminofluorene . -
pubmed
The purpose of the present study was to examine the inhibitory effect of
caffeine on
hepatocarcinogenesis and to determine the responsive dose of
caffeine on
hepatocarcinogenesis in young male
ACI rats . -
pubmed
Animals given a diet containing
2 - acetylaminofluorene (
2 - AAF ) for 12 weeks and then a basal diet and tap water containing
caffeine for 18 weeks showed statistically significant decreases in the incidence , multiplicity ( the number of
hepatic tumors per
rat ) and histological grade compared with
rats fed a diet containing carcinogen for 12 weeks followed by tap water alone . -
pubmed
The inhibitory effect of
caffeine on
hepatocarcinogenesis in
rats was found when
caffeine was administered during the initiation phase . -
pubmed
The hemodynamic consequences of multifocal
atrial tachycardia in an elderly
woman are presented . -
pubmed
Hormone therapy remains the cornerstone of treatment for
patients with locally advanced or metastatic
prostate cancer . -
pubmed
However , to date there is still no effective therapy for
patients who have
hormone refractory disease . -
pubmed
Clinical evaluation of
human placental extract ( placentrex ) in radiation - induced
oral mucositis . -
pubmed
To evaluate
human placental extract in the treatment of radiation
mucositis involving the oral / oropharyngeal region , a prospective randomized study was carried out in 120
patients with
squamous cell carcinoma of the head and neck from August 1997 to March 1999 . -
pubmed
The study was conducted in
patients receiving radical external radiation therapy , planned for = & gt ; 60 Gy/30 F/6 weeks , who developed grade 2 radiation
mucositis ( patchy
mucositis ) during radiation treatment . -
pubmed
A subjective decrease in
pain was observed in 48/60 ( 80 % ) of
patients in the
placentrex group compared with 22/60 ( 36.7 % ) in the control group . -
pubmed
Human placental extract appears to be effective in the management of radiation - induced
oral / oropharyngeal mucositis and especially in controlling subjective symptoms . -
pubmed
RESULTS : 21
patients ( 2.0 % ) experienced
dislocation after total hip arthroplasty , 17 during activities of daily living and three after a fall . -
pubmed
RESULTS : Of the 22
individuals ,
ataxia was the initial symptom in 21 ;
seizure disorders developed in 11 , mostly within several years following the onset of
ataxia . -
pubmed
A brain magnetic resonance imaging or computed tomographic scan showed
cerebellar atrophy in all
patients examined . -
pubmed
An electroencephalogram demonstrated
epileptiform discharges in 4 of 8
patients studied . -
pubmed
We hypothesized rhythmic back pressure on a
patient in the prone position with sternal counter - pressure ( termed reverse CPR here ) would increase intra - thoracic pressure and in turn
systolic blood pressure (
SBP ) during
cardiac arrest versus standard CPR . -
pubmed
Eligible
patients had suffered
circulatory arrest and failed standard CPR for at least 30 min . -
pubmed
Postnatal
protein malnutrition affects inhibitory avoidance and risk assessment behaviors in two models of
anxiety in
rats . -
pubmed
These results suggest that malnourished
animals are less anxious and/or more impulsive as measured by these two
animal models and that
malnutrition seems to affect differently behavioral strategies underlying fear and
anxiety responses . -
pubmed
OBJECTIVE : To investigate correlation of
Helicobacter pylori ( Hp ) infection with symptoms and gastric electrical activity in
patients with
functional dyspepsia (
FD ) . -
pubmed
METHODS : Sixty
patients with
FD confirmed by gastroscopy and pathology were enrolled in this study . -
pubmed
[ Further observations in
rabbit fibromatosis induced by
Rous virus ] . -
pubmed
[ CHANGES IN THE CARDIOVASCULAR SYSTEM OF
SUBJECTS WITH
ANKYLOSING SPONDYLITIS ] . -
pubmed
Quantitative assessment of
gastric antrum atrophy shows restitution to normal histology after
Helicobacter pylori eradication . -
pubmed
The aims of the present study were to evaluate the applicability of this method for the grading of antral
atrophy and to study the effect of
Helicobacter pylori eradication on the antral mucosa . -
pubmed
METHODS : Antrum biopsy specimens were collected from 71
gastroesophageal reflux disease patients at baseline and after 3 and 12 months . -
pubmed
The present data indicate that
gastric mucosal atrophy is reversible , since almost all cases showed regression of VPGL after
H. - pubmed
PURPOSE : To describe central corneal thickness among
patients diagnosed with
congenital aniridia . -
pubmed
METHODS : We identified
patients carrying the clinical diagnosis of
congenital aniridia and performed complete ophthalmic examinations . -
pubmed
This may lead to incorrect estimates of intraocular pressure by applanation techniques and highlights the importance of monitoring
patients with
aniridia for the development of
glaucoma through regular gonioscopy and optic nerve examination . -
pubmed
Management of a
patient with a
forearm fracture and
median nerve injury . -
pubmed
OBJECTIVES :
Patients with
peripheral nerve injury may demonstrate long - lasting impairments and functional limitations . -
pubmed
In this case report , we describe the diagnosis of a
patient with a
peripheral nerve injury and a conventional plan of care , along with the novel intervention of neuromuscular electrical stimulation ( NMES ) . -
pubmed
BACKGROUND : The
patient was a 21 - year - old
male who sustained a
forearm fracture that was complicated by
injury to the anterior interosseous branch of the median nerve . -
pubmed
Infection of
man with
Bacterium tularense . -
pubmed
Myocardial viability in
patients with
ischemic cardiomyopathy - evaluation by 3 - D integration of myocardial scintigraphic data -- and coronary angiographic data . -
pubmed
PURPOSE : To determine the prevalence of viable myocardium in
patients with
ischemic cardiomyopathy and , to evaluate the value of three - dimensional ( 3 - D ) fusion imaging of myocardial scintigraphic and angiographic data to assign
coronary artery lesions to the corresponding viable and nonviable myocardial territory . -
pubmed
RESULTS : Based on the presence of viable dysfunctional myocardium , 54 % of
patients with
ischemic cardiomyopathy may be considered for coronary revascularization . -
pubmed
CONCLUSION : In
patients with end - stage
coronary artery disease scintigraphic imaging is most important in the decision - making process . -
pubmed
Here we report that in
mouse fusiform cells , spikes evoked 5 ms after parallel - fiber excitatory postsynaptic potentials ( EPSPs ) led to long - term potentiation ( LTP ) , whereas spikes evoked 5 ms before EPSPs led to long - term
depression ( LTD ) of the synapse . -
pubmed
Thyrotoxicosis remains a frustrating condition for the young
person , family , and health professionals involved . -
pubmed
Most
patients with
thyrotoxicosis will need many years of drug therapy if the thyroid gland is not removed surgically or destroyed by
radioiodine . -
pubmed
Successful use of intralesional and intravenous
cidofovir in association with
indole-3 - carbinol in an 8 - year - old
girl with
pulmonary papillomatosis . -
pubmed
We report the history of an 8 - year - old
girl who was treated for suspected
lung lesions of
respiratory papillomatosis with
Indole-3 - Carbinol , local and intravenous injections of
Cidofovir for 27 months . -
pubmed
This is the first report where a complete cure of the
lung lesions occurred in a
child , and was sustained for at least 24 months . -
pubmed
METHODS : NDL was performed in 108
patients unselected for
breast carcinoma risk and then was repeated after 2 - 14 months ( median , 8 months ) if the initial lavage was classified as atypical . -
pubmed
After excluding breasts with an incident
carcinoma , there were 32
patients ( 30 % ) with either mild or marked
atypia . -
pubmed
Virological and molecular characterization of a mammalian orthoreovirus type 3
strain isolated from a
dog in Italy . -
pubmed
A mammalian orthoreovirus (
MRV )
strain was isolated from a pup with
fatal diarrhea , which had a concurrent
infection by canine parvovirus type 2 . -
pubmed
A total of 110 fecal samples , 56 nasal and 31 ocular swabs from dogs with
diarrhea or nasal / ocular discharge were tested by a nested - PCR assay specific for reoviruses , and no sample was found to contain
MRV RNA , a finding that is apparently in contrast with the seroprevalence ( 25.77 % ) observed in
dogs . -
pubmed
The hESC - derived NK cells acquire the ability to lyse
human tumor cells by both direct cell - mediated cytotoxicity and Ab - dependent cellular cytotoxicity . -
pubmed
It was found that the excess of cardiovascular events and mortality occurs already in diabetic
patients with persistent
microalbuminuria , but is particularly evident in macroalbuminuric
diabetic patients and results not only from
end - stage renal failure (
ESRF ) but rather from
cardiovascular disease (
CVD ) , the latter mainly in
type 2 diabetic patients . -
pubmed
Several traditional risk factor for
atherosclerosis has been identified in diabetic
patients with micro- or
macroalbuminuria including elevated blood pressure levels ,
dyslipidemia and procoagulatory state associated with
endothelial dysfunction . -
pubmed
Thus , multiple mechanisms are involved in the development and progression of
cardiovascular complications both in micro- and macroalbuminuric
diabetic patients and all these mechanisms should be regarded as the target for therapeutic intervention . -
pubmed
The causal analysis showed a depressed baroreflex regulation in resting
patients , with reduced gain and increased latency from SP to RR , and a drop of the baroreflex coupling immediately before
syncope . -
pubmed
Most
patients die from distant
metastases , and the overall 5 year survival rate is approximately 4 % . -
pubmed
CONCLUSION : This supports the concept that
patients with primary
melanoma of the oesophagus treated should be carefully followed up . -
pubmed
Three of 300 ( 1 % )
PD patients presented with
HFS compared with 0/300 ( 0 % ) controls . -
pubmed
The mean age of the three
PD patients with
HFS was 68.7 + /- 8.0 ( 60 - 76 ) years , with the majority having left - sided
HFS . -
pubmed
All three
patients developed
HFS symptoms at around the onset of
PD and they were significantly older than the 100
patients with
HFS alone ( P < 0.05 ) . -
pubmed
Our study demonstrated no significant increased risk of
HFS amongst the general
PD population and hence
HFS symptoms are unlikely to be of clinical importance for most
PD patients . -
pubmed
Rosiglitazone could improve clinical outcomes after coronary stent implantation in nondiabetic
patients with
metabolic syndrome . -
pubmed
BACKGROUND : Recent studies have shown that
thiazolidinediones (
TZDs ) could reduce in - stent restenosis and improve clinical outcomes in
patients with
type 2 diabetes after coronary stent implantation . -
pubmed
It remains unclear whether nondiabetic
patients with
metabolic syndrome after stenting could also benefit from the treatment with TZDs . -
pubmed
METHODS : Three hundred and sixty
patients with
metabolic syndrome who underwent coronary stent implantation were randomly assigned to a
rosiglitazone group ( n = 180 ) or a control group ( n = 180 ) . -
pubmed
CONCLUSION :
Rosiglitazone could reduce the risk of the adverse cardiovascular event and improve clinical outcomes in nondiabetic
patients with
metabolic syndrome after coronary stent implantation . -
pubmed
A
child with liver kidney microsomal ( LKM ) antibody positivity underwent successful liver transplantation for
liver failure secondary to
GCH with Coomb 's positive
hemolytic anemia . -
pubmed
PATIENTS AND METHODS : Pancreas - sparing distal duodenectomy ( PSDD ) was performed in 14
patients with infrapapillary duodenal
neoplasms between 1991 - 2002 , and the clinical outcome is reviewed . -
pubmed
RESULTS : There were 9
men and 5
women of median age 56 years , who presented with
iron - deficiency anaemia ( n = 8) ,
gastric outlet obstruction ( n = 4 ) ,
anaemia and
gastric outlet obstruction ( n = 1 ) ,
epigastric pain or mass ( 1 each ) . -
pubmed
There were 11 malignant
neoplasms (
adenocarcinoma 5 , stromal
tumour 4 , recurrent
seminoma 1 ,
plasmacytoma 1 ) , 2 benign
neoplasms ( villous
adenoma ,
lipoma ) and 1
patient with
steroid - induced
ulceration . -
pubmed
CONCLUSIONS : Provided there is a minimum 1 - cm clearance at the papilla , PSDD is a useful alternative to formal pancreatoduodenectomy in
patients with unusual
neoplasms arising from the third and fourth parts of the duodenum . -
pubmed
Genotyping
glycogen storage disease type II and type V in
cattle reared in the Czech Republic . -
pubmed
Genotyping was carried out for
glycogen storage disease type II and type V in seven
cattle breeds . -
pubmed
Of the symptomatic
patients , 14.0 % had
atherothrombotic lesions in more than 1 vascular bed , with 0.8 % having lesions in 3 areas : brain , heart , and peripheral arteries . -
pubmed
Helminths down - regulate
inflammation and may prevent development of several
autoimmune illnesses , such as
inflammatory bowel disease . -
pubmed
PURPOSE OF REVIEW :
Patients treated for
cancer may be at risk for
osteoporosis and
fracture . -
pubmed
Evaluation and treatment of
patients with
cancer treatment - induced
bone loss should lead to fewer
fractures . -
pubmed
This review will help clinicians learn to identify , evaluate and treat
cancer patients at risk . -
pubmed
RECENT FINDINGS : Survivors of childhood
cancers and
patients made hypogonadal by treatment for
breast or prostate cancer are clearly at risk for
osteoporosis and
fracture . -
pubmed
Bisphosphonates prevent
bone loss in many
patients at risk . -
pubmed
SUMMARY : For many
cancer patients , treatment with
calcium ,
vitamin D , and
bisphosphonates will likely decrease the consequences of
cancer treatment - induced
bone loss , namely
fractures . -
pubmed
In this work , we evaluate the significance of disease extent in a group of
patients with
CIN 2 to 3 that was completely excised by LEEP ( ie , endocervical and ectocervical margins were negative ) . -
pubmed
A sustained - release formulation of
doxycycline hyclate (
Atridox ) prevents simultaneous
infection of
Anaplasma phagocytophilum and
Borrelia burgdorferi transmitted by
tick bite . -
pubmed
MATERIALS AND METHODS : we studied 163
patients ( mean age 65.5 years ; 101
men and 62
women ) referred for multidetector computed tomography coronary angiography ( MDCT - CA ) to rule out
CAD . -
pubmed
Plaque in
patients with nonsignificant disease was mixed in 65 % , soft in 18 % and calcified in 17 % . -
pubmed
Doxorubicin - based chemotherapy for the palliative treatment of adult
patients with locally advanced or metastatic
soft - tissue sarcoma : a meta - analysis and clinical practice guideline . -
pubmed
To make recommendations for the use of
doxorubicin - based chemotherapy in
patients with
soft - tissue sarcoma . -
pubmed
The recommendations apply to
patients with symptomatic unresectable locally advanced or
metastatic soft - tissue sarcoma who are candidates for palliative chemotherapy . -
pubmed
Systemic
aminoglycoside treatment in
rodent models of
retinitis pigmentosa . -
pubmed
[ Use of
mebendazole for
helminthiases in
chickens and
geese ] . -
pubmed
Two groups of
geese , 20 in each group , were treated against
Hymenolepis - infection using
Mebendazol in food for 6 consecutive days . -
pubmed
In vivo studies and histopathological examination revealed that eyes of
rabbits treated with nanoemulsion showed clearer healing of
corneal chemical ulcer with moderate effective inhibition of polymorph nuclear leukocytic infiltration ( PMNLs ) compared with nanoparticles preparation . -
pubmed
Bleb leakage was the most common complication in each group and developed in approximately 4 % of
subjects in each group per year ( P = 0.33 , log - rank test ) . -
pubmed
Clinical assessment of peripheral muscle function in
patients with
chronic obstructive pulmonary disease . -
pubmed
DESIGN : Sixteen
COPD patients ( forced expiratory volume during the first second 38 + /- 15 % predicted ) and 6 controls underwent magnetic resonance imaging of the thigh , muscle strength and endurance , and exercise tolerance assessments . -
pubmed
Six
COPD patients ( 16 + /- 2.5 kg m(-2 ) ) ( P & lt ; 0.05 ) presented reduced thigh mass ( COPDLQ ) , whereas 10
patients with normal quadriceps mass ( COPDNQ ) and all controls had identical mass distribution ( 22 + /- 2.4 kg m(-2 ) ) . -
pubmed
COPDLQ
patients had lower muscle function and lower exercise tolerance than both COPDNQ and controls ( P & lt ; 0.05 each ) , but muscle strength corrected by mass was similar between
COPD patients ( COPDLQ 0.59 + /- 0.12 and COPDNQ 0.55 + /- 0.10 Nm kg(-1 ) m(-2 ) ) and controls ( 0.62 + /- 0.04 Nm Kg(-1 ) m(-2 ) ) . -
pubmed
CASE REPORT : A 16 - year - old
woman developed a sudden onset of
dystonic symptoms which affected her higher and lower limbs , bulbar muscles , together with severe
dysarthria and
dysphagia . -
pubmed
The proteasome inhibitor
bortezomib has a striking clinical benefit in
patients with
multiple myeloma . -
pubmed
We have used the well - characterized 5TGM1
murine model of
myeloma to investigate
myeloma growth within bone and response to the proteasome inhibitor
bortezomib in vivo . -
pubmed
Myeloma cells freshly isolated from the bone marrow of
myeloma - bearing
mice were found to have an increase in proteasome activity and an enhanced response to in vitro proteasome inhibition , as compared with pre - inoculation
myeloma cells . -
pubmed
Treatment of
myeloma - bearing
mice with
bortezomib resulted in a greater reduction in
tumor burden when the
myeloma cells were located within the bone marrow when compared with extra - osseous sites . -
pubmed
Two
patients received superficial second - degree
burns that did not require corrective treatment . -
pubmed
paratuberculosis is an important pathogen that causes
Johne ' s disease in animals and also has been implicated as a possible cause of
Crohn ' s disease in
humans , but little is known about the protective immune responses to this microorganism . -
pubmed
Using
mouse models , we determined the contribution of DCs to altered hepatic immunity in
fibrosis and investigated the role of DCs in modulating the inflammatory environment within the fibrotic liver . -
pubmed
OBJECTIVE : To investigate the
recurrence of the neck and survival incidence of clinically possible positive lateral cervical nodes in
patients with well - differentiated
papillary thyroid cancer and the essentiality of the perforation of modified radical neck dissection . -
pubmed
RESULT : Fifty nine
patients in group A were treated with the modified radical neck dissection , and 22
patients of them were found
metastasis in lateral cervical nodes with VI area . -
pubmed
47
patients in group B had
metastasis in lateral cervical nodes though without performing VI area neck dissection ( 40.5 % ) , and the survival rate of 5 years was 99.3 % . -
pubmed
Worldwide , there are several approaches for the prevention of
cervical cancer , and in the near future it is likely that
human papillomavirus (
HPV ) vaccination and
HPV - based screening will be complementary strategies . -
pubmed
HPV vaccination programs targeted at young girls have been widely implemented in several affluent countries , and currently available data confirm the long - term efficacy of the VLP - based vaccines against
HPV - related disease over periods of up to 8 years . -
pubmed
However , a significant
HPV vaccination - induced reduction in
cervical cancer burden is not likely to be realized for at least 10 to 15 years . -
pubmed
BACKGROUND :
Deep amblyopia is a recognized cause of monocular
visual deficit in
children with a high rate of poor compliance with conventional occlusion therapy . -
pubmed
This study evaluates a new occlusion technique that can be used for
children with failed
amblyopia treatment . -
pubmed
METHODS : In a prospective study , surgical
silicone - eyelid closure was done for 15
children ( age : 4 to 6 years ; median age : 5.2 years ) with a history of
deep amblyopia and poor compliance with occlusion methods . -
pubmed
Complications were seen in 8
patients : marginal eyelid
irritation and
erythema in 6 and suture break in 2 . -
pubmed
TRial of an Educational intervention on
patients ' knowledge of
Atrial fibrillation and anticoagulant therapy , INR control , and outcome of Treatment with
warfarin ( TREAT ) . -
pubmed
DISCUSSION : More data is needed on the clinical benefit of educational intervention with
AF patients receiving
warfarin . -
pubmed
One of the least studied but most important areas in this regard is the effects of embryo culture on epigenetic phenomena , and on genomic imprinting in particular , because assisted reproduction has been linked to development of the
human imprinting disorders Angelman and Beckwith - Wiedemann syndromes . -
pubmed
Patients with nondiploid
tumors had higher hazard rates for both
tumor progression and
death ( p = 0.007 and p = 0.016 , respectively ) ; however , the prognostic information of DNA ploidy was not additive to
tumor grade . -
pubmed
We studied 282
patients with
CAD without ST elevation and preserved systolic function . -
pubmed
No statistically significant difference was observed between
patients with
SA and controls ( 21.2 + -6.8 pg / mL ) . -
pubmed
Improvements of cardiac electrophysiologic stability and
ventricular fibrillation threshold in
rats with
myocardial infarction treated with cardiac stem cells . -
pubmed
We sought to investigate the electrophysiologic characteristics and
ventricular fibrillation threshold in
rats with
myocardial infarction by treatment with allogeneic cardiac stem cells . -
pubmed
INTERVENTIONS :
Myocardial infarction was induced in 20 male
Sprague - Dawley rats . -
pubmed
CONCLUSIONS : Cardiac stem cells may modulate the electrophysiologic abnormality and improve the
ventricular fibrillation threshold in
rats with
myocardial infarction treated with allogeneic cardiac stem cells and cardiac stem cell express markers that suggest muscle , endothelium , and vascular smooth muscle phenotypes in vivo . -
pubmed
Atrial electromechanical interval can identify
patients with paroxysmal
atrial fibrillation and is associated with CHADS2 score and peak velocity of left atrial appendage . -
pubmed
INTRODUCTION : It is difficult to discriminate
patients with and without
paroxysmal atrial fibrillation (
PAF ) . -
pubmed
The aim of our study was to investigate whether the electromechanical interval is a useful parameter to identify
patients with
PAF . -
pubmed
METHODS AND RESULTS : A total of 297
patients (
PAF group = 103 ; control group = 194 ) with mean age of 59.4 + - 12.4 years were enrolled . -
pubmed
Investigation of
human JC and BK polyomaviruses in
breast carcinomas . -
pubmed
We have previously showed the presence of the
simian virus 40 (
SV40 ) and the
mouse mammary
tumor virus (
MMTV)-like in a significant proportions of Tunisian
breast carcinomas . -
pubmed
However , to date there are no published studies concerning evaluation of the possible implication of the
human polyomaviruses JC (
JCV ) and BK (
BKV ) in breast
carcinomas . -
pubmed
The presence of
JCV and
BKV DNA was investigated by PCR in a 123 primary breast
carcinomas and matched adjacent
non - tumor breast tissues . -
pubmed
JCV T - antigen DNA was detected in 23 % of
breast carcinoma cases ; however , all cases were negative for
BKV . -
pubmed
To the best of our knowledge , this is the first study demonstrating the presence of
JCV in a subset of breast
carcinomas . -
pubmed
The second
patient was a 76 - year old male , moderate smoker and drinker , who had been complaining about
swelling in the neck . -
pubmed
Cerebral hypoperfusion and
white matter disease in healthy elderly and
patients with
Alzheimer ' s disease . -
pubmed
PURPOSE : To compare the clinical results and repair integrity of arthroscopic rotator cuff repair between a knotless and a conventional knot - tying suture bridge technique for
patients with full - thickness
rotator cuff tears and to evaluate retear patterns in the cases with structural failure after arthroscopic repair by magnetic resonance imaging ( MRI ) . -
pubmed
METHODS : After arthroscopic repair for medium - sized
rotator cuff tears , 110
patients available for postoperative MRI evaluation at least 6 months were enrolled in this study . -
pubmed
Representativeness of the
dabigatran ,
apixaban and
rivaroxaban clinical trial populations to real - world
atrial fibrillation patients in the United Kingdom : a cross - sectional analysis using the General Practice Research Database . -
pubmed
OBJECTIVE : Three oral anticoagulants have reported study results for
stroke prevention in
patients with
atrial fibrillation (
AF ) (
dabigatran etexilate ,
rivaroxaban and
apixaban ) ; all demonstrated superiority or non - inferiority compared with
warfarin ( RE - LY , ARISTOTLE and ROCKET - AF ) . -
pubmed
RESULTS : 83 898
patients with
AF were identified in the GPRD . -
pubmed
Preperimetric
glaucoma patients had significant reductions of ONH perfusion compared to normals . -
pubmed
Porcine parvovirus (
PPV ) is a major causative agent of
reproductive failure in
swine , which currently affects the
swine industry worldwide . -
pubmed
These mechanistic studies of
fiber toxicity have proceeded along two lines : those demonstrating biochemical mechanisms by which fibers induce disease and those investigating
human susceptibility . -
pubmed
Although asbestos exerts a genotoxic effect at certain concentrations in vitro , a positive response in these tests does not indicate that the chemical is likely to produce an increased risk of
carcinogenesis in exposed
human populations . -
pubmed
Altogether 257
obese children and adolescents ( RBMI>120 ) and 94 adults , who were never
obese or
overweight ( BMI<25 ) , were studied . -
pubmed
A 16 - year - old
woman with
MELAS developed
fever and
myoclonic epilepsy which improved with conventional anti -
epileptic drugs . -
pubmed
Use of NSAIDs in treating
patients with
arthritis . -
pubmed
In
patients with risk factors for NSAID
toxicity , using the lowest dose of a drug with a short half - life only when it is needed is likely to be the safest treatment option . -
pubmed
These results provide new insight into the mechanism by which the seahorse - derived peptide suppresses invasive properties of
human cancer cells . -
pubmed
Erythroderma is generalized
exfoliative dermatitis , which involves more than 90 % of the
patient 's skin . -
pubmed
Clinically , the
patients presented with non - specific symptoms such as
chest pain , or were entirely asymptomatic . -
pubmed
None of the
patients had a history of
autoimmune syndrome . -
pubmed
We retrospectively reviewed 91
focal cortical dysplasia patients ( 55 % female ; median age : 19 years ( interquartile range 8 - 34 ) ; median
seizure duration : 108 months ( interquartile range 36 - 204 ) ) with
chronic epilepsy who underwent surgery . -
pubmed
Of the 91
patients , there were 50
patients with
ILAE focal cortical dysplasia type Ib , 41 with
ILAE focal cortical dysplasia type Ic , 63 with
Palmini et al focal cortical dysplasia type IA , and 28 with Palmini et al focal
cortical dysplasia type IB . -
pubmed
Patients with
pSS were classified accordingly with the grade of inflammatory lesions as I = low - grade ( low focus score of 1 or 2 ) , II = intermediate - grade ( focus score of 3 - 6 ) and III = extensive
inflammation in the MSG ( high focus score of 12 ) . -
pubmed
At P12 , cKO
mice exhibited
cardiac hypertrophy and impaired contraction of the left ventricle . -
pubmed
While this works well for cell culture studies and
leukaemia mouse models , fluorescent reporters are poorly suited for
animals with solid
tumours -- the most common
tumour types in
cancer patients . -
pubmed
We demonstrate that secreted luciferase activities can be measured robustly in the blood stream of
tumour - bearing
mice to accurately quantify , in a minimally invasive manner , the dynamic evolution of two genetically distinct
tumour subclones in preclinical
mouse models of
tumour development ,
metastasis and therapy . -
pubmed
Among 14,411 transplanted
patients the incidence of
BCs was 23 % . -
pubmed
Since the completion of the
human genome project and with the increased availability of high - throughput genotyping , multiple genetic risk factors for substance - related disorders , including
alcohol dependence , have been identified , but not all results could be replicated . -
pubmed
OBJECT : While the incidence of a recurrent
hemorrhage is highest within 24 hours of
subarachnoid hemorrhage (
SAH ) and increases with the severity of the clinical grade , a recurrent
hemorrhage can occur anytime after the initial
SAH in
patients with both good and poor clinical grades . -
pubmed
Therefore , the authors adopted a 24 - hour - a - day , formal protocol , emergency treatment strategy for
patients with ruptured
aneurysms to secure the
aneurysms as early as possible . -
pubmed
METHODS : During an 11 - year period , a total of 1224
patients with a ruptured
aneurysm were managed using a strategy of broadly defined early treatment between 2001 and 2004 ( Period B , n=423 ) , a mixture of early or emergency treatment between 2005 and 2007 , and a formal emergency treatment protocol between 2008 and 2011 ( Period A , n=442 ) . -
pubmed
CONCLUSIONS :
Patients with
ruptured aneurysms may benefit from a strategy of emergency application of surgical clip placement or endovascular coiling due to the reduced incidence of recurrent
bleeding and improved clinical outcomes . -
pubmed
Of the 3445 eligible
persons ( mean age 72.0 + -7.1 years ) available for cross - sectional analyses , 8.9 % ( n = 307 ) had prevalent clinical
heart failure . -
pubmed
In longitudinal analyses , 1989 eligible
persons ( mean age 70.0 + -5.8 years ) were followed for an average of 6.5 + -0.4 years , of which 4.6 % ( n = 91 ) had prevalent or incident clinical
heart failure . -
pubmed
Medial epicondyle fractures in
children . -
pubmed
In
patients with displaced
fractures , fixation yields stability , functional range of motion , and the ability to return to previous activity levels , including sports . -
pubmed
We present a case of a 9 - year boy who accidentally ingested a long paper pin , which spontaneously passed in 26 h. This case is being reported to highlight the successful spontaneous passage of a 4 cm long sharp
foreign body in a
child . -
pubmed
We aimed to investigate the effect of probable risk factors on the positive rate of the repeated transurethral resection of
bladder tumor performed 4 - 6 weeks after an initial TURBT in
patients with
non - muscle invasive bladder cancer in China . -
pubmed
METHODS : 134
patients with
non - muscle invasive bladder cancer who underwent repeated TURBT within 4 - 6 weeks after an initial resection were included in this study . -
pubmed
As showed in the manuscript , of the total 134
patients , 52 had residual
tumor , and upgrading occurred in 41
patients . -
pubmed
The progression and recurrence rate was significantly higher in
patients with residual
tumor in Re TURBT . -
pubmed
OBJECTIVE : As part of the Physicians ' Observational Work on
Patient Education According to their Vascular Risk ( POWER ) survey , we used Framingham methodology to examine the effect of an
eprosartan - based regimen on total
coronary heart disease (
CHD ) risk in diabetic
patients recruited in Canada . -
pubmed
METHODS :
Patients with new or uncontrolled
hypertension ( sitting
systolic blood pressure [
SBP ] & gt;140 mmHg with
diastolic blood pressure & lt;110 mmHg ) were identified at 335 Canadian primary care practices . -
pubmed
RESULTS : We identified an intention - to - treat
diabetes population of 195
patients . -
pubmed
Most
diabetic patients were prescribed two or more antihypertensive drugs throughout the survey . -
pubmed
Intermuscular fat increased with
weight loss ,
weight gain , or with no weight change with age in
humans . -
pubmed
The relationship between
leanness and higher proportions of INTMF fat in
pigs was not observed in
human studies and was not corroborated by other
pig studies . -
pubmed
Lipin1 deficiency results in immature adipocyte development in
human lipodystrophy . -
pubmed
Moreover , the designed SHPE apparatus demonstrates potential application in
wound dressing by in situ e - spinning fibers onto
human skin directly . -
pubmed
White matter volume in the brainstem and inferior parietal lobule is related to motor performance in
children with
autism spectrum disorder : A voxel - based morphometry study . -
pubmed
In this study , we used voxel - based morphometry ( VBM ) to investigate which WM regions correlate with motor performance in
children with
ASD , and whether the WM volume in those brain regions differed between children with
ASD and typically developing ( TD )
children . -
pubmed
The subjects included 19
children with
ASD and 20 TD controls . -
pubmed
Children with
ASD showed poorer motor performance than did the controls . -
pubmed
These findings suggest that structural changes in the WM in the brainstem and left inferior parietal lobule may contribute to poor motor performance in
children with
ASD . -
pubmed
However , these benefits are not obvious in cardiac surgery
patients with intraoperative
anemia . -
pubmed
Similarly ,
postoperative complications did not differ between
patients who received a red cell transfusion and matched
patients who did not ( adjusted odds ratio 0.94 , confidence interval 0.72 - 1.23 ) . -
pubmed
Occipital nerve stimulation ( ONS ) is a surgical approach to treat
patients with medically intractable chronic
headache disorders . -
pubmed
In this study , the analgesic efficacy of transcutaneous electrical nerve stimulation ( TENS ) was tested for 1 to 3 months in 41
patients with pharmacologically intractable
headache disorders of various origins , using a new technique of electrode placement over the occipital nerve . -
pubmed
ONS electrodes were subsequently implanted in 33
patients (
occipital neuralgia [ n=15 ] ,
cervicogenic headache [ n=7 ] ,
cluster headache [ n=6 ] , chronic
migraine [ n=5 ] ) who had responded at least moderately to TENS . -
pubmed
Implanted ONS may be a valuable therapeutic option in the long term for
patients with pharmacologically intractable chronic
headache . -
pubmed
This preoperative test could particularly be useful in
patients with
chronic migraine , in whom it may be difficult to indicate an invasive technique of cranial neurostimulation . -
pubmed
Stromal cells with a myofibroblast phenotype present in the normal
human esophagus are increased in
individuals with
gastro - esophageal reflux disease (
GERD ) . -
pubmed
The antimicrobial activity as well as the
cytotoxicity were specific for the different test microorganisms ( Gram - positive and Gram - negative bacteria and
fungi ) and model eukaryotic cells (
osteosarcoma , fibroblast , and keratinocyte cells ) , respectively , and both were depending on the
ZnTiO3 concentration . -
pubmed
BACKGROUND : Surgery remains the standard of care for
patients with
colorectal liver metastases (
CLMs ) , with a 5 - year survival rate approaching 35 % . -
pubmed
Perioperative chemotherapy confers a survival benefit in selected
patients with
CLMs . -
pubmed
Airborne Fine Particulate Matter Induces Oxidative Stress and
Inflammation in
Human Nasal Epithelial Cells . -
pubmed
Exposure to PM2.5 is associated with increased risk of many
human diseases , including chronic and
allergic rhinitis , but the underlying molecular mechanism for its toxicity has not been fully elucidated . -
pubmed
These results suggest that PM2.5 may induce oxidative stress and inflammatory responses in
human nasal epithelial cells , thereby leading to
nasal inflammatory diseases . -
pubmed
Contribution of the patient -
horse relationship to
substance use disorder treatment : Patients ' experiences . -
pubmed
Few have reported on the patient 's own perspective and none have reported specifically on the
human -
horse relationship in
substance use disorder (
SUD ) treatment and its implications for health and well - being . -
pubmed
The objective of the present study was to characterize the liver oil extracted from the
deep sea shark ,
Echinorhinus brucus , caught from Central Indian Ocean and to evaluate its
cytotoxic effect on
neuroblastoma cell line (
SHSY-5Y ) . -
pubmed
The oil of
Echinorhinus brucus also showed high in vitro
cytotoxic effect against the
human neuroblastoma cell line (
SHSY-5Y ) and the IC50 value laid between 35 and 45 ng . -
pubmed
METHODS : The records of 80
trauma patients admitted to the Anaesthesia , General Surgery and Neurosurgery ICUs between June 1 , 2012 and July 15 , 2014 were included in the study . -
pubmed
CONCLUSION : The most important factor affecting mortality in this particular
trauma - ICU
patient population from Syrian civil war was the physiological condition of patients on admission . -
pubmed
Genital tract lesions in sexually mature Gottingen
minipigs during the initial stages of experimental
vaginal infection with
Chlamydia trachomatis serovar D. BACKGROUND :
Chlamydia is one of the most common
sexually transmitted diseases in
humans worldwide , causing chronic lesions in the reproductive tract . -
pubmed
This study employs a novel sexually mature
minipig model to investigate the initial histopathological changes following
vaginal infection with
Chlamydia trachomatis serovar D. RESULTS : A vaginal inoculation resulted in an
infection primarily affecting the lower genital tract . -
pubmed
In this study , we observe a similar pattern of local immune response /
inflammation following experimental inoculation suggesting this
porcine model shows promise as a model for translational
chlamydia research . -
pubmed
ILC2s as key players in the development of
allergic rhinitis (
AR ) have been proved , however , the effect of subcutaneous immunotherapy ( SCIT ) with
dermatophagoides pteronyssinus extract ( Der p - SCIT ) on ILC2s in
AR patients is not clear . -
pubmed
This study aimed to investigate the response of ILC2s of peripheral blood in
house dust mites ( HDM)-sensitized Chinese
patients with
AR who received SCIT with
Der P extract . -
pubmed
RESULTS : Among 40
participants , 9
AR patients were assigned to the untreated group , 24
AR patients receiving Der p - SCIT were assigned to the immunotherapy group , and 7 healthy controls without symptoms of
AR were assigned to healthy control group . -
pubmed
CONCLUSIONS : The present study highlighted the suppression of Der p - SCIT on ILC2s in HDM -
AR patients . -
pubmed
METHODS : Fifty - three
patients with
NERD , who had persistent
reflux symptoms despite taking double - dose PPI , were included in this study . -
pubmed
RESULTS : One of the 53
patients had
EoE , and 4 had primary
esophageal motility disorder . -
pubmed
The main determinant of
disease progression is efficiency of the CTL response to
Human T lymphotropic virus types I ( HTLV-1 ) . -
pubmed
Based on case numbers and the potential impact on
human health , the Centers for Disease Control and Prevention ( CDC ) categorised
toxocarosis as one of the most important neglected
parasitic diseases . -
pubmed
METHODS : We retrospectively reviewed 62 consecutive Lenke 1
AIS patients who underwent posterior spinal arthrodesis using all - pedicle screw instrumentation with a minimum follow - up of 24 months . -
pubmed
CONCLUSIONS : Both low density and high density pedicle screw instrumentation achieved satisfactory
deformity correction in Lenke 1
AIS patients . -
pubmed
Seven and 10
patients had preoperative
anemia in the MI - TLIF group and the O - TLIF group , respectively , and 32 and 45 postoperatively . -
pubmed
A correct understanding of
HBL can ensure
patient safety and improve postoperative rehabilitation . -
pubmed
Methods : From January 2014 to October 2016 , Eighty - four
patients with stenosing
tenosynovitis were randomly divided into the open decompressionand group ( 42 cases ) and percutaneously looped thread transection group ( 42 cases ) in Department of Orthopedics , Affiliated Laiwu Hospital of Taishan Medical College . -
pubmed
A phase 3 , double - blind , randomized placebo - controlled efficacy and safety study of
abiraterone acetate in chemotherapy - naive
patients with
mCRPC in China , Malaysia , Thailand and Russia . -
pubmed
Objective : This double - blind , placebo - controlled phase 3 study was designed to compare efficacy and safety of
abiraterone acetate +
prednisone (
abiraterone ) to
prednisone alone in chemotherapy - naive , asymptomatic or mildly symptomatic
metastatic castration - resistant prostate cancer (
mCRPC )
patients from China , Malaysia , Thailand and Russia . -
pubmed
Conclusion : Interim analysis confirmed favorable benefit - to - risk ratio of
abiraterone in chemotherapy - naive
men with
mCRPC , consistent with global study , thus supporting use of
abiraterone in this
patient population . -
pubmed
BACKGROUND : Mechanisms for the development of
food allergy in neonates are unknown but clearly linked in
patient populations to a
genetic predisposition to
skin barrier defects . -
pubmed
After sensitization ,
mice received oral challenge with food allergen , and then
inflammation , inflammatory mediators , and
anaphylaxis were measured . -
pubmed
RESULTS : We define development of
inflammation , inflammatory mediators , and food allergen - induced
anaphylaxis in neonatal
mice with skin barrier mutations after brief concurrent cutaneous exposure to food and environmental allergens . -
pubmed
CONCLUSION : These studies uncover mechanisms for food
allergy sensitization and
anaphylaxis in neonatal
mice that are consistent with features of
human early - life exposures and genetics in
patients with clinical
food allergy and demonstrate that changes in barrier function drive development of
anaphylaxis to food allergen . -
pubmed
METHODS : We conducted a retrospective study , which included
CML patients , who were above 18 years of age and who until May 2013 had used at least for 2 years ( 24 months ) the original
imatinib , and following that used at least for 24 months one of the generic
imatinib medicines . -
pubmed
DNA methylation of genes regulating appetite and prediction of
weight loss after bariatric surgery in
obese individuals . -
pubmed
RESULTS : At baseline ,
type 2 diabetes was diagnosed by OGTT in 13
patients . -
pubmed
Further evidence for depletion of peripheral blood natural killer cells in
patients with
schizophrenia : A computational deconvolution study . -
pubmed
Our analysis was based on publicly available data from peripheral blood DNA methylation profiling in 711
schizophrenia patients and 713 healthy controls ( 2 independent samples ) . -
pubmed
METHODS : Two hundred fifty - three
patients with metastatic
breast cancer were enrolled in this prospective , multicentre study . -
pubmed
OMWW dietary supplementation can be a nutritional strategy to improve
chicken performance and health , prevent
intestinal damage , enhance innate immunity and regulate
cholesterol metabolism and fat deposition . -
pubmed
After examining each potential risk factor in a separate multivariable model , only Day-10 surrogate Hospital
Anxiety and
Depression Scale score ( beta coefficient = 1.02 ; 95 % CI , 0.73 - 1.30 ) and
patient unresponsiveness ( beta coefficient = 8.39 ; 95 % CI , 0.83 - 15.95 ) were associated with higher IES - R scores . -
pubmed
CONCLUSIONS : Among surrogate decision - makers for chronically
critically ill patients , high
anxiety and
depression scores and
patient unresponsiveness on or near Day 10 of mechanical ventilation are risk factors for
PTSD symptoms at 90 days . -
pubmed
Included
patients had & gt;=12 months of serial
creatinine laboratories and a baseline estimated
glomerular filtration rate ( eGFR , by the Modification of Diet in
Renal Disease Study equation ) & gt;=60 mL / min/1.73 m2 . -
pubmed
RESULTS : Adjusted mean eGFR was significantly higher for non - CHB vs. untreated
CHB patients ( eGFR 87.4 vs. 85.6 , P= 0.004 , n = 580 , median follow - up = 82 months ) . -
pubmed
A significant difference in adjusted mean eGFR between untreated vs.
entecavir (
ETV)-treated
CHB patients ( eGFR 85.1 vs. 83.5 , P= 0.02 , n = 340 , median follow - up = 70 months ) was found among non - cirrhotic
CHB . -
pubmed
Among treated
CHB , there was no difference in adjusted mean eGFR between non - cirrhotic vs. cirrhotic
patients ( eGFR 77.0 vs. 76.5 ; P= 0.66 , n = 112 , median follow - up = 58 months ) . -
pubmed
Methods : The present randomized , clinical trial study was conducted on 82
women who complained of
hot flashes during their menopause period . -
pubmed
Urgent TAVR was defined as a procedure performed in the same hospitalization in
patients emergently admitted due to
cardiac arrest , severe
acute decompensated heart failure ,
acute coronary syndrome , or repeated
syncopal episodes . -
pubmed
Materials and methods
Gastric subepithelial lesions in multiple topographic locations of the stomach were simulated in seven live
pigs . -
pubmed
Only
individuals at risk for
vitamin D deficiency should be screened . -
pubmed
Deregulation of metallothionein genes has been reported in various
human tumors . -
pubmed
METHODS : Fourteen eyes of 14
patients diagnosed with
type 3 neovascularization were studied . -
pubmed
We included all
patients from the years 2006 to 2018 with severe
frostbite injury who had received appropriate imaging for diagnosis :
Tc99 scan alone ( N = 82 ) , microangiography alone ( N = 22 ) , and both Tc99 and microangiography ( N = 26 ) . -
pubmed
Environmental and occupational exposure to industrial chemicals has been linked to toxic and
carcinogenic effects in animal models and
human studies . -
pubmed
CASE REPORT We present the case of a 67 - year - old
woman with subacute
cutaneous lupus erythematosus (
SCLE ) and
EM - like lesions who fulfilled all the criteria for
Rowell ' s syndrome . -
pubmed
The
patient had
lupus arthritis for two years and was treated with oral
methylprednisolone 8 mg / day and
hydroxychloroquine 200 mg / day . -
pubmed
The
patient also had
arterial hypertension with no current treatment ,
osteoporosis , and an
L1 vertebral fracture . -
pubmed
and
ceftriaxone 2 g / day for the
superinfection with
Ps . - pubmed
We present a case of
metastatic melanoma in a 69 - year - old
man as the underlying etiology of his
intussusception . -
pubmed
The
patient remains alive without
recurrence . -
pubmed
BET 1 : Efficacy of different techniques using a metered - dose inhaler with Spacer to relieve symptoms in
children with acute
asthma . -
pubmed
Resveratrol , a natural
plant product , has been found to exert anti - inflammatory properties and attenuate the development of
murine colitis . -
pubmed
Lastly , analysis of public data from
human patients with
ulcerative colitis (
UC ) revealed that miR-31 expression was significantly increased when compared to controls . -
pubmed
CONCLUSIONS : Together , the current study demonstrates that
resveratrol - mediated attenuation of
colitis may be regulated by miR-31 through induction of Tregs and miR-31 may serve as a therapeutic target for
human colitis . -
pubmed
Sensitization of spinal
itch transmission neurons in a
mouse model of chronic
itch requires an astrocytic factor . -
pubmed
BACKGROUND : Chronic
itch is a highly debilitating symptom among
patients with
inflammatory skin diseases . -
pubmed
Interestingly , increases in excitation were attenuated by suppressing the reactive state of SDH astrocytes , which are known to be reactive in
patients with chronic
itch conditions . -
pubmed
Impressive effect of
cisplatin monotherapy on a
patient with heavily pretreated triple - negative
breast cancer with poor performance . -
pubmed
The present case report documents the successful use of
cisplatin monotherapy to manage a heavily pretreated
TNBC patient showing poor response to therapy . -
pubmed
After three cycles of
cisplatin treatment , the
patient 's metastatic lesions dramatically improved without any major
toxicity , and she completed 17 cycles with good response . -
pubmed
This case study indicates that
patients with heavily pretreated
TNBC can potentially achieve a good response to
cisplatin monotherapy . -
pubmed
Substantial undocumented
infection facilitates the rapid dissemination of novel coronavirus (
SARS - CoV-2 ) . -
pubmed
Here , we use observations of reported
infection within China , in conjunction with mobility data , a networked dynamic metapopulation model , and Bayesian inference , to infer critical epidemiological characteristics associated with
SARS - CoV-2 , including the fraction of undocumented
infections and their contagiousness . -
pubmed
Crowd management
today needs to minimise the chances of occurrence of stampedes , fires and other disasters and also to deal with the ongoing threat of terrorism and outbreak of
communicable diseases like
EBOLA ,
HIV Aids ,
Swine Influenza H1N1 , H1N2 , various strands of flu ,
Severe Acute Respiratory Syndrome (
SARS ) and
Middle Eastern Respiratory Syndrome (
MERS ) . -
pubmed
Combined Microscopic and Metabolomic Approach to Characterize the Skeletal Muscle Fiber of the Ts65Dn
Mouse , A Model of
Down Syndrome . -
pubmed
In this study , we used a combined methodological approach involving light and electron microscopy , as well as nuclear magnetic resonance spectroscopy metabolomics , to investigate morphology and composition of the quadriceps muscles in the Ts65Dn
mouse , a model of
DS , to identify structural and/or functional
trisomy - associated alterations . -
pubmed
Finally , our previous study highlights the mechanisms by which the transition from
AKI to
CKD does not occur in female
rats commonly as it does in male
rats . -
pubmed
BACKGROUND : Control of
bleeding during laparoscopic liver resection ( LLR ) is important for
patient safety . -
pubmed
shawi ES-62 produced ex vivo was functional and protective in a
murine model of
arthritis . -
pubmed
Endotracheal Intubation in
Patients With
COVID-19 Infection : Expert Panel - Based Consensus Recommendations . -
pubmed
To study the behavior of
micrometastases - how they resist initial treatments and then awaken from a dormant state - we utilize the Legacy LiverChip , an all -
human ex vivo hepatic microphysiological system . -
pubmed
The functional liver bioreactor , comprising hepatocytes and non - parenchymal cells in a 3D microperfused culture format , mimics the dormant - emergent metastatic progression observed in
human patients : ( a ) a subpopulation of
cancer cells spontaneously enter dormancy , ( b ) cycling cells are eliminated by standard chemotherapies , while quiescent dormant cells remain , and ( c ) chemoresistant dormant cells can be stimulated to emerge . -
pubmed
--
Carcinine had a
vasodepressive action upon
Vertebrates . -
pubmed
High frequency of aberrant expression of
Moloney murine leukemia virus in
clonal infections . -
pubmed
Clones of cells were isolated from single virus - single cell
infections of
NIH / 3T3 cells with
Moloney murine leukemia virus . -
pubmed
A variety of defective clones were also isolated following
infection of
rat cells with
Moloney virus . -
pubmed
The ratio of
tumor uptake to fat tissue uptake was correlated with the age of the
patient , menopausal status , presence of axillary
metastases at time of mastectomy , and the response to endocrine therapy if
metastases were presented . -
pubmed
There was no correlation between a higher uptake of
estradiol by the
tumor and age of the
patient , menopausal status , or presence of axillary
metastases at time of mastectomy . -
pubmed
21
patients with
hyperlipoproteinaemias of type IIa and IIb were treated with
D - thyroxin ( 4 mg / die ) after a placebo phase . -
pubmed
Fine structure of meiotic prophase chromosomes and modified synaptonemal complexes in diploid and
triploid Rhoeo spathacea . -
pubmed
The urinary excretion of
nucleosides of ribonucleic acid by
patients with advanced
cancer . -
pubmed
By means of a sensitive and specific method utilizing gas - liquid chromatography , the excretion levels for three
nucleosides , degradation minor base products of ribonucleic acid , primarily transfer ribonucleic acid , were determined in 24 - hour urine specimens from over 200
patients with solid
tumor malignancies . -
pubmed
When compared to normal control values , elevated levels of these compounds were found for
patients in each of several
tumor types studied . -
pubmed
Fourteen
patients with
radiculomyelitis following acute
haemorrhagic conjunctivitis (
AHC ) were seen in Bangkok during October to December 1974 . -
pubmed
Most
patients developed
weakness of extremities 2 weeks after
AHC . -
pubmed
Six
patients received
corticosteroid treatment but apart from relief of
pain no significant improvement was seen . -
pubmed
Motor
weakness in 10
patients was less at the end of 2 months , but in 4 it remained unchanged . -
pubmed
Most
patients with relatively early
glaucomatous damage can be satisfactorily managed with topically or orally administered medications . -
pubmed
Of 40
patients with
thrombotic thrombocytopenic purpura , 17 were treated with plasma exchange , 15 with exchange transfusions , and 6 with both types of therapy . -
pubmed
This study supports the hypothesis that plasma exchange has significantly improved the prognosis of
patients with
thrombotic thrombocytopenic purpura . -
pubmed
A 45 - year - old
woman was admitted suffering from
headache ,
weight loss ,
asthenia ,
pedal edema , and
amenorrhea . -
pubmed
About half of the
patients with
central nervous system ( CNS ) leukemia , when submitted systematically to neuroradiological investigations , presented intracerebral solid deposits . -
pubmed
Reconstituted
vesicular stomatitis virus (
VSV ) envelopes were formed by solubilization of the viral envelope with
Triton X-100 followed by removal of detergent by direct addition of SM2 biobeads . -
pubmed
Only one
patient had worsening of symptoms postoperatively , which was secondary to
intracerebral hemorrhage . -
pubmed
Furthermore , we show that in one particular region of the optic pathway that the retinal
ganglion cell axons avoid in normal
animals ( i.e. -
pubmed
A 25 - year - old
man with
juvenile onset diabetes presented with
rhinoorbital mucormycosis . -
pubmed
The in vivo
murine mutation assay should be a useful system for
genotoxicity testing and may be of particular value in establishing risk estimates for
human populations exposed to genotoxins . -
pubmed
An associated
patent ductus arteriosus was present in a total of 81
patients . -
pubmed
A review was made of the records of 24 consecutive
trauma patients ( aged 55 - 94 years ) who had under gone radiographic examinations and a positive bone image of the femur or pelvis . -
pubmed
[ State of the cerebral hemodynamics in
ischemic stroke patients with
hypertension ] . -
pubmed
[ Significance of the volume of circulating blood and its components for assessing the state of
patients with
uterine fibromyoma at the stage of surgical treatment ] . -
pubmed
Further studies on the effect of a transplanted
methylcholanthrene - induced
fibrosarcoma on humoral immunity in CBA
mice . -
pubmed
[ Agreement between the bacteriological characters of certain
strains of the
gallinarum - pullorum group of
Salmonella and their sensitivity spectrum to bacteriophages obtained beginning with lysogenous
strains of the same group ] . -
pubmed
Fasciola hepatica infection in
cattle . -
pubmed
[ Detection of
diabetes mellitus in
patients with
myocardial infarct ] . -
pubmed
[ A
paratyphoid B infection of
human origin as a cause of abortion in a
cow ] . -
pubmed
17
patients with moderate to severe
Raynaud ' s phenomenon were entered into a 6 week randomised double - blind crossover study to compare the efficacy of
nifedipine with that of placebo . -
pubmed
12 of the
patients regarded
nifedipine as effective in reducing the frequency and severity of
Raynaud ' s phenomenon . -
pubmed
Pharmacologic management of
glaucoma in the
dog . -
pubmed
It elicits vocalization in palpated
rats and
ataxia in
dogs . -
pubmed
induced significant
osteoporosis in
C3H / St ( Ha ) female mice after 3 months of treatment . -
pubmed
Vulvovaginitis caused by
Yersinia enterocolitica . -
pubmed
The
animals of the main series ( 7
dogs ) with a veno - venous connection of the membrane oxygenator ( MO ) tolerated
hypoxia quite well for 2 hours . -
pubmed
One hundred
children with
cancer and
bacterial sepsis were observed for one month after completion of antibiotic treatment for subsequent episodes of
infection . -
pubmed
Of the 26
neutropenic patients not receiving
TMP -
SMZ 23 ( 88 % ) had episodes of
infection , whereas 4 ( 36 % ) of the 11 given the drug had recurrent or re -
infection episodes ( P = less than 0.001 ) . -
pubmed
A difference of similar significance was observed in the non -
neutropenic patients . -
pubmed
Infections in
children in
relapse of their
malignancy were twice as frequent in those not receiving the drug as in those who received it ( P = less than 0.02 , greater than 0.01 ) . -
pubmed
This study shows that the administration of
TMP --
SMZ after
bacterial sepsis reduces the number of infectious episodes in neutropenic and non - neutropenic
patients , with the exception of the
non - neutropenic patient in remission . -
pubmed
Production of
prostaglandins in homogenates of kidney medullae and cortices of spontaneously
hypertensive rats fed menhaden oil . -
pubmed
Menhaden oil ( MO ) , whose
polyunsaturated fatty acids consist mainly of
( n-3 ) fatty acids , was fed to spontaneously
hypertensive rats to determine the effect of
( n-3 ) fatty acid on the in vitro production of
prostaglandins produced from
arachidonic acid ( 20:4[n-6 ] ) . -
pubmed
During a 1 - year period 10
newborns with
myelodysplasia were seen . -
pubmed
Disulfiram has been shown to decrease the incidence of
arrhythmias in
rabbits exposed to
trichloroethylene . -
pubmed
significantly decreased the time spent in
arrhythmia compared to control
rabbits , 120 - 180 s following intravenous administration of 4 mg / kg
barium chloride . -
pubmed
The effect of
prodectin was examined in 79
patients with
coronary disease after a course of treatment , and in 16 normal subjects . -
pubmed
Therefore the drug appears to be advisable for
patients with
coronary disease exposed to increased information inflow which requires greater concentration of their attention in short time . -
pubmed
Twenty - seven
patients with 28
aseptic nonunions were treated with reamed intramedullary ( IM ) nailing of the tibia and were followed for at least 1 year postoperatively . -
pubmed
OBJECTIVE : To address the frequency of side effects of
Ritalin therapy in
children with
attention deficit hyperactivity disorder (
ADHD ) using the Barkeley Side Effects Questionnaire ( BSEQ ) in a clinical setting . -
pubmed
PATIENTS : 234 consecutive
children aged 5 through 15 years who met the Diagnostic and Statistical Manual of
Mental Disorders ( 3rd ed , revised ) criteria for
ADHD were enrolled . -
pubmed
CONCLUSION : The BSEQ proved to be clinically effective in tracking
Ritalin side effects and should be incorporated into the routine evaluation and monitoring of
ADHD patients for whom stimulants are prescribed . -
pubmed
Labiatae allergy : systemic reactions due to ingestion of
oregano and
thyme . -
pubmed
BACKGROUND : There are no cases described in the medical literature of systemic
allergic reactions due to
oregano (
Origanum vulgare ) or
thyme (
Thymus vulgaris ) . -
pubmed
OBJECTIVE : We describe three
systemic allergic reactions caused by
oregano and
thyme in the same patient . -
pubmed
Realization of the potential of foodborne substances to reduce the
human burden of
cancer will only be achieved with better measurement of dietary exposures and funding of multidisciplinary research in this area commensurate with its importance . -
pubmed
Typing of nosocomial
strains of
Serratia marcescens : comparison of restriction enzyme cleaved genomic DNA fragment ( PFGE ) analysis with bacteriocin typing , biochemical profiles and serotyping . -
pubmed
Based on the analysis of PFGE patterns against the background of epidemiological data , the number of nosocomically significant
strains of
S. - pubmed
OBJECTIVES : Determine possible differences in clinical manifestations , laboratory findings and neuroimaging results in
tuberculous meningitis patients with and without
HIV infection . -
pubmed
RESULTS : There were 24
HIV - infected patients and 14 without
HIV infection . -
pubmed
Age ( median age = 33 years for the
HIV group vs. 53 for the non -
HIV group ) , sex ratio ( 3 vs. 0.75 ) , and prior history of
tuberculosis ( 46 % vs. 43 % ) were similar in both groups . -
pubmed
Clinical presentation was similar for
headache ( 83 % in
HIV group vs. 50 % in non -
HIV group ; p = 0.02 ) and
confusion ( 54 % vs. 93 % in non -
HIV group p = 0.05 ) . -
pubmed
Remodeling with
neointima formation in the
mouse carotid artery after cessation of blood flow . -
pubmed
Using a denuding -
injury procedure , we recently reported that
intimal lesions can be induced in the carotid artery of outbred
mice . -
pubmed
The technical challenge associated with achieving complete denudation and the relatively small size of the developing lesions prompted us to design the present model of
neointima formation and
vascular remodeling in the carotid artery of the inbred FVB
mouse strain . -
pubmed
[ Artificial nutrition of
patients with
toxic epidermal necrolysis (
Lyell syndrome ) ] . -
pubmed
The authors report the case of a 30 - year - old
man treated with
toxic epidermal necrolysis . -
pubmed
The
patient was admitted with denudated skin surface similar to second - degree
burn that covered 90 per cent of the
patient 's body surface . -
pubmed
The
patient was isolated and treated , receiving sterile
wound care , broad spectrum antibiotic and
corticosteroid . -
pubmed
The early recognition of the disease , the intensive care and nutritional therapy may improve the survival of
patients with
toxic epidermal necrolysis . -
pubmed
Overall , both groups of
patients experienced less
pain than expected , except on days 3 and 4 . -
pubmed
Patients in the
metronidazole group had significantly less
pain than those in the placebo group on days 5 , 6 , and 7 ( p = 0.004 , p = 0.02 , and p = 0.006 ) . -
pubmed
INTERPRETATION : Prophylactic
metronidazole in diathermy DCH suppressed secondary
pain around days 5 - 7 and increased
patient satisfaction and earlier return to work . -
pubmed
To qualify water , TMM - I ( integral indication of micro - organisms ) , TMM - C ( coccal indication ) , and TMM - BP ( indication of blue
pus Pseudomonas aeroginosa ) will be necessary and sufficient . -
pubmed
PATIENTS AND METHODS : Between January 1995 and December 1997 , 60
patients with
pituitary adenomas were operated on at Okayama University Hospital . -
pubmed
The extradural temporopolar approach was used for 5
patients who had a giant
pituitary adenoma invading the cavernous
sinus and parasellar regions . -
pubmed
The 5
patients were
women aged from 32 to 62 years and presented with a
visual dysfunction . -
pubmed
Four
patients had hormonally non - functioning
pituitary adenomas and one had a growth - hormone secreting
pituitary adenoma . -
pubmed
In this study 41 new
HIV-1 strains , representing the majority of the described envelope subtypes of
HIV-1 ( A to H ) , were genetically characterized in the nef region . -
pubmed
In the 20
patients who had both nebulisers , the mean percentages of
stomach deposition for the Ventstream and Optimist nebulisers were 11.8 % and 1.6 % , respectively . -
pubmed
40
epileptic 5 - 12 year - old
children as well as 9 healthy
children ( a control group ) were examined . -
pubmed
To determine whether the Neo gene also confers resistance to vertebrate
ototoxicity , the sensitivity of cochlear hair cells to
neomycin was evaluated in
mice with a targeted insertion of Neo . -
pubmed
Organotypic cultures of the organ of Corti , isolated from neonatal wild - type
mice and two
strains of
mice carrying the Neo gene , were cultured for 72 h in the absence ( controls ) or in the presence of 200 microM
neomycin . -
pubmed
Establishment and characterization of
human pancreatic carcinoma lines with a high metastatic potential in the liver of
nude mice . -
pubmed
To investigate of
human pancreatic cancer metastasis to the liver , a
pancreatic carcinoma line ,
HPC-3 , was injected into the spleens of
nude mice . -
pubmed
The
mice were observed to have liver
metastasis in 6 of 6 ( 100 % ) cases injected with
HPC-3H4 , whereas the rate was 0 % at 3 weeks after the intrasplenic injection of
HPC-3 . -
pubmed
This approach can be used in conjunction with existing information to assist clinicians in the management of
patients with
acute low back pain . -
pubmed
In a retrospective study , all
patients who underwent surgery for
abdominal aortic aneurysm were reevaluated by preoperative diagnostic and therapeutic interventions for
cardiovascular disease . -
pubmed
Of 603
patients operated upon for
abdominal aortic aneurysm between 1980 and 1996 , 449 had surgery on an elective basis and 154 as an emergency . -
pubmed
Preoperative diagnostic studies for
coronary artery disease were performed on elective
patients and were positive in 76.8 % ( 1980 - 1989 , 76.1 % , 1990 - 1996 , 77.5 % ) . -
pubmed
Let us present a case of recurrent
paranoid psychotic episodes in a
patient with a history of abuse of & lt;<
ecstasy>> ; (
MDMA :
3 , 4 - methylenedioxymethamphetamine ) , that persisted after a long withdrawal time , that , in our opinion , after an exhaustive differential diagnosis , may be attributed to that consumption . -
pubmed
The permanent changes in the evoked response audiograms and sensory cell populations were the same in Groups 1 , 2 and 3 that were exposed to the
traumatic noise , regardless of whether or not the
animals were ever subjected to the toughening noise or whether the toughening noise preceded or followed the traumatic noise . -
pubmed
The dose - effect relationship for
morphine and
vomiting after day - stay tonsillectomy in
children . -
pubmed
A dose - response curve for intravenous
morphine and
vomiting was investigated in
children having day - stay tonsillectomy . -
pubmed
Fifty - five of these 164
children vomited and 20
children required an overnight stay in hospital because of
vomiting . -
pubmed
Our data suggests that lower doses of
morphine are associated with a decreased incidence of
emesis after tonsillectomy in
children . -
pubmed
METHODS :
Patients presenting with
musculoskeletal pain requiring NSAID treatment and without previous exposure to NSAID or pre - existing
ulcers were recruited . -
pubmed
Patients with
non - ulcer dyspepsia and
H. - pubmed
Excluding the 50 women whose babies were delivered for
fetal distress ( leaving 1228
women for analysis ) , the epidural rate was 93 % , range 81 - 98 % , and the cesarean delivery rate was 14 % , range 8 - 34 % . -
pubmed
Logistic regression analyses revealed that ( odds ratio , 95 % confidence interval )
patient age ( 1.7 , 1.2 - 2.4 ) ,
birth weight ( 1.001 , 1.001 - 1.002 ) , induction of labor ( 1.9 , 1.3 - 2.7 ) , non - Caucasian ( 1.9 , 1.2 - 2.9 ) and the obstetrician group , ( P=0.002 ) , were independently associated with the risk of cesarean delivery , but epidural analgesia was not ( 1.6 , 0.7 - 3.6 ) . -
pubmed
Alzheimer ' s disease (
AD ) is the most common
human neurodegenerative disorder characterized by the progressive
deterioration of cognition and memory in association with the presence of
senile plaques ,
neurofibrillary tangles , and massive loss of neurons . -
pubmed
It is now generally accepted that massive
neuronal death due to apoptosis is a commmon characteristic in the brains of
patients suffering from
neurodegenerative diseases , and apoptotic cell
death has been found in neurons and glial cells in
AD . -
pubmed
Patients with profound
sensorineural hearing loss due to mtDNA defects should be considered as candidates for cochlear implantation when they no longer benefit from conventional hearing aids . -
pubmed
We report two
children , sisters , both with severe , recurrent
hemorrhagic complications from
factor VII deficiency , successfully treated with orthotopic liver transplantation . -
pubmed
Among
rats in the 4 TPN groups surviving 7 days , there were no significant differences in
body weight change ( minus 3 - 4 % ) , spleen or lung weight , extent of liver regeneration ( 61 - 66 % ) . -
pubmed
Among
rats surviving for 7 days ,
body weight change ( minus 3 - 5 % ) , liver regeneration ( 67 - 70 % ) , and liver tests were similar in both groups . -
pubmed
Representation of
pain and somatic sensation in the
human insula : a study of responses to direct electrical cortical stimulation . -
pubmed
We studied painful and non - painful somaesthetic sensations elicited by direct electrical stimulations of the insular cortex performed in 43
patients with
drug refractory temporal lobe epilepsy , using stereotactically implanted depth electrodes . -
pubmed
In
humans , both a posterior and an anterior
pain - related cortical area have been described within the insular cortex using functional imaging . -
pubmed
The effect of 450 mg / day
propafenone for two weeks on
premature ventricular contractions ( PVCs ) was studied in combination with an assessment of heart rate ( HR ) dependency of PVCs using Holter ECG monitoring in
patients with more than 720 PVCs per day . -
pubmed
Human infection with the
sheep liver fluke
Fasciola hepatica is a global
zoonosis that usually parallels the prevalence of
infection in
sheep and other ruminants . -
pubmed
Therefore , we report a case of acute
human fascioliasis and review the pathogenesis , diagnosis , and treatment of this disease in a recently arrived immigrant . -
pubmed
The risk factors affecting the outcome in 50
children with
tuberculous meningitis were evaluated over a period of 20 months . -
pubmed
Younger age ,
tonic posturing ,
papilloedema , focal
neurological deficit and stage at presentation were found to affect adversely the prognosis independently in
children with
tuberculous meningitis . -
pubmed
The presence of glomerular pathologic findings attributable to
hypercalcemia has been observed in only a few
patients and therefore has been considered an unusual finding . -
pubmed
In the current study ,
calcium deposition within glomeruli was investigated in 2
patients with extreme elevations in serum
calcium levels and
hypercalcemic nephropathy . -
pubmed
The study material consisted of a renal biopsy specimen from a 31 - year - old
woman (
patient 1 ) who had
T - cell lymphoma /
leukemia and a serum
calcium level of 20.2 mg / dL ( 5.0 mmol / L ) and autopsy kidney specimens from a 19 - year - old
woman (
patient 2 ) who was being evaluated for
primary hyperparathyroidism and a
calcium level of 18.4 mg / dL ( 4.6 mmol / L ) . -
pubmed
Glomerular calcinosis may also be recognized as an additional cause of segmental
glomerulosclerosis and
nephrotic range
proteinuria in
patients with extremely high levels of serum
calcium . -
pubmed
Effect of simulated field deposits of
gamma - BHC and
dieldrin on suceptible , hybrid and resistant
strains of
Anopheles gambiae Giles . -
pubmed
Variability of incidence and clinical manifestation of
mouse hereditary muscular dystrophy on heterogeneous genetic backgrounds . -
pubmed
2,3,7,8 - Tetrachlorodibenzo - p - dioxin (
TCDD ) is a widespread environmental contaminant , that has been linked with a variety of deleterious effects on
human health , including increased
cancer rates and
reproductive anomalies . -
pubmed
Patients with isolated
deep venous thrombosis or
deep venous thrombosis with concomitant
pulmonary embolism seemed to have similar benefit . -
pubmed
Antiestrogen
tamoxifen seems useful in
HCC patients . -
pubmed
A pilot study was performed to evaluate the effect of
all - trans retinoic acid associated with
tamoxifen and
vitamin E on
patients with advanced
HCC . -
pubmed
PATIENTS AND METHODS : Fifteen consecutive
patients with advanced
HCC were included in the study . -
pubmed
Pain and
asthenia were improved in the majority of
patients . -
pubmed
CONCLUSION : A combination therapy of
all - trans retinoic acid ,
tamoxifen and
vitamin E increases the survival rate and ameliorates the clinical outcome in
patients with inoperable
HCC . -
pubmed
108 ambulatory
patients with clinical signs of
conjunctivitis and
blepharoconjunctivitis were enrolled in the study . -
pubmed
The adjustable suture procedures performed during a 5 - year period , on
non - thyroid eye disease patients , were matched to non - adjustable cases according to the type and aetiology of
strabismus and the magnitude of deviation . -
pubmed
The authors conclude that there is currently insufficient evidence that
patients , without
thyroid eye disease , benefit from the longer and potentially uncomfortable procedure of adjustable suture
strabismus surgery to support its rapidly growing use and that a prospective randomised controlled trial is indicated . -
pubmed
PURPOSE OF REVIEW : The purpose of this paper is to review current
animal models that may be useful for studying
cancer associated with
human immunodeficiency virus infection . -
pubmed
RECENT FINDINGS : Several
animal models , primarily using
mice and
monkeys , have been developed that recapitulate aspects of the pathology of various
malignancies in
human acquired immune deficiency syndrome . -
pubmed
The incidence of
DVT from positive radionuclide venography was 24 % ( 16/67
patients ) and
PE was 12 % ( 8/67 patients ) . -
pubmed
Between 1999 and 2001 , 89
patients with
peripheral arterial disease categorized as TASC C ( n=37 ) and D ( n=52 ) underwent percutaneous interventional reconstruction and stent implantation . -
pubmed
OBJECTIVE : To describe the unmasking of
pheochromocytoma in a
patient treated with
amisulpride and
tiapride . -
pubmed
CASE SUMMARY : A 42 - year - old white
man developed acute
hypertension with severe
headache and
vomiting 2 hours after the first doses of
amisulpride 100 mg and
tiapride 100 mg . -
pubmed
CONCLUSIONS : As of March 24 , 2005 , this is the first reported case of
amisulpride- and
tiapride - induced
hypertensive crisis in a
patient with
pheochromocytoma . -
pubmed
Infarction of the right hemisphere in a
patient with
antiphospholipid antibody syndrome . -
pubmed
Hemicraniectomy as a surgical treatment for intracranial pressure following large
ischemic lesions is widely practiced in selected
patients . -
pubmed
Postoperative cauda equina syndrome in
patients undergoing single - level lumbar microdiscectomy . -
pubmed
In this paper , the authors report two cases of
postoperative cauda equina syndrome in
patients undergoing single - level de novo lumbar microdiscectomy in which intraoperative electrophysiological monitoring was used . -
pubmed
Postoperative magnetic resonance images obtained in both
patients , and a lumbar myelogram obtained in the second one revealed no signs of conus medullaris or
nerve root compression . -
pubmed
The authors ' findings support the proposition that intraoperative SSEP monitoring may be useful in predicting the development of
cauda equina syndrome in
patients undergoing lumbar microdiscectomy . -
pubmed
Disappearance of
HCV after cessation of immunosuppression in a patient with
ulcerative colitis and renal transplantation . -
pubmed
PATIENTS AND METHODS :
Disseminated epithelial prostate cancer cells were isolated from bone marrow aspirates from 69
men with
localized prostate cancer before RP , by magnetic column - chromatography enrichment , followed by isolation of fluorescently labelled epithelial cells by micropipetting . -
pubmed
We report the case of a young
man with a recurrent
idiopathic priapism , successfully treated with
methoxamine intracarvenosal self - injections . -
pubmed
OBJECTIVE : The goals of the study were to : 1 ) determine the acceptability of
STI testing among individuals seeking services at shelters in 2 midsized southeastern cities ; 2 ) evaluate the prevalence of
chlamydia , gonorrhea ,
syphilis , and
HIV among these individuals ; and 3 ) assess the proportion that subsequently learned their test results and received timely and appropriate treatment if warranted . -
pubmed
The rate of CT in city B was significantly higher than city A ( 15.0 % vs. 6.4 % , P = 0.02 ) ; however , similar rates were found for
GC ( 5.0 % vs. 3.2 % ) , primary and secondary
syphilis ( 0.08 % vs. 1.4 % ) , and
HIV ( 0.07 % vs. 0.06 % ) . -
pubmed
CONCLUSION : We found that shelter clients were receptive to
STI testing , even for
HIV , with most positive cases notified and successfully treated . -
pubmed
First reported case of dialysis - related
peritonitis due to
Escherichia vulneris . -
pubmed
This is the first reported case of
peritonitis due to
E. - pubmed
Our patient is a 62 - year - old
woman with longstanding
systemic arterial hypertension and
angina pectoris . -
pubmed
An ongoing clinical trial is designed to determine whether
NO - ASA can inhibit early stages of colon
carcinogenesis in
subjects at risk for
colon cancer . -
pubmed
We assessed left ventricular ( LV ) systolic function with DTI in 45
human immunodeficiency virus ( HIV )- infected patients without any heart - related symptoms and in 30 healthy control subjects . -
pubmed
Thromboprophylaxis for
patients at high risk of
VTE . -
pubmed
The cell
death in male
Wister rats were studied from 6 h until 4 days after global
cerebral ischemia induced by transient 2 - vessel
carotid occlusion with
hypotension for 15 min . -
pubmed
Modulation of experimental
osteoporosis in
rats by the antioxidant beverage effective microorganism - X ( EM - X ) . -
pubmed
The levels of serum
estradiol ( E(2 ) ) and the bone density of the middle and epiphysis of femurs were assessed in order to determine the effect of EM - X on
osteoporosis in ovariectomized
rat ( an animal model of
postmenopausal osteoporosis ) . -
pubmed
Patients determined to have
prostate adenocarcinoma underwent radical retropubic prostatectomy . -
pubmed
Myelin contains many axonal outgrowth inhibitory components which contribute to regeneration failure after
neuronal injury in the
mammalian central nervous system ( CNS ) . -
pubmed
Fifty - two
patients with
MS were enrolled in the study . -
pubmed
We found that 22
patients had primary progressive , 18
patients had relapsing - remitting and 12
patients had secondary progressive
MS . -
pubmed
Detrusor sphincter dyssynergia was found in 25 % of
patients , and
detrusor hyporeflexia was detected in 6 % . -
pubmed
Decrease in viral load at weeks 12 and 24 in
patients with
chronic hepatitis B treated with
lamivudine or
adefovir predicts virological response at week 48 . -
pubmed
CONCLUSION : The decrease in viral DNA at weeks 12 and 24 can predict VR at one year in
patients with
chronic hepatitis B treated with
LAM or
ADF . -
pubmed
GABA concentration in
schizophrenia patients and the effects of antipsychotic medication : a proton magnetic resonance spectroscopy study . -
pubmed
Among the right handed
schizophrenia patients , the
GABA concentration in the ltBG was significantly higher in
patients taking typical antipsychotics ( 1.25+/-0.24 mmol / l ) than in those taking atypical antipsychotics ( 1.03+/-0.24 mmol / l , p=0.026 ) . -
pubmed
It is possible that medication effects conceal inherent differences in
GABA concentrations between
schizophrenia patients and healthy controls . -
pubmed
Pump - treated
type 1 diabetes subjects were randomized to one bolus waveform for one full day of three meals and then crossed over to the other bolus waveforms . -
pubmed
A rational use of glucocorticoids in
patients with early
arthritis has a minimal impact on bone mass . -
pubmed
INTRODUCTION : Glucocorticoid ( GC)-induced
osteoporosis is a frequent complication in
patients with
rheumatoid arthritis . -
pubmed
METHODS : Data from 116
patients in our early
arthritis register were analyzed ( 90
women ; median age , 52.5 years , interquartile range ( IQR , 38.5 - 66 ) ; 6 - month median disease duration at entry ( IQR , 4 - 9 ) ) . -
pubmed
RESULTS : Of the
patients with early
arthritis studied , 67 % received GCs during the 2 - year follow - up . -
pubmed
CONCLUSIONS : The frequent use of GCs as a " bridge therapy " in
patients with early
arthritis does not seem to be associated with relevant loss of bone mass . -
pubmed
Health care - associated and community - associated
methicillin - resistant
Staphylococcus aureus infections : A comparison of definitions . -
pubmed
MATERIAL AND METHODS : There were studied 459
heart failure patients admitted in the Cardiology Department of a general hospital in Cluj - Napoca , Romania . -
pubmed
Goal - oriented cognitive rehabilitation for
people with early - stage
Alzheimer disease : a single - blind randomized controlled trial of clinical efficacy . -
pubmed
Primary airway epithelial cultures from
children are highly permissive to
respiratory syncytial virus infection . -
pubmed
This included 573 renal ablation procedures performed in 533
patients to treat 633
tumors . -
pubmed
Reverse genetics viruses for
influenza vaccine production usually utilize the internal genes of the egg - adapted
A / Puerto Rico / 8 / 34 ( PR8 )
strain . -
pubmed
Influence of gender on long - term mortality in
patients presenting with non - ST - elevation
acute coronary syndromes undergoing percutaneous coronary intervention . -
pubmed
Deep sequencing detected a potential bioterrorism agent ,
Francisella tularensis , in a
human abscess sample ( Iwaki-08 ) of unknown etiology . -
pubmed
The in vivo effects of both Comp.1 and Comp.2 were evaluated on hippocampal neurogenesis in olfactory bulbectomized ( OBX )
mice , an experimental
depression and
dementia animal model . -
pubmed
OBJECTIVE : To analyze the outcome of
patients after surgical or nonoperative treatment of
Hadley type IIA odontoid fractures . -
pubmed
METHODS : We analyzed the records of 46
patients at an average of 64 years of age at the time of
injury . -
pubmed
Infection - associated nuclear degeneration in the
rice blast fungus Magnaporthe oryzae requires non - selective macro - autophagy . -
pubmed
BACKGROUND : The
rice blast fungus Magnaporthe oryzae elaborates a specialized
infection structure called an appressorium to breach the
rice leaf surface and gain access to plant tissue . -
pubmed
AIMS : To describe the longitudinal course of
thrombocytopenia and risks for
bleeding in veteran
patients with
non - hepatitis C - related CLD . -
pubmed
CONCLUSIONS : Among veteran
patients with non -
hepatitis C - related
CLD , baseline platelet counts of 50,000 to 100,000 / mul increased subsequent risks for both incident severe
thrombocytopenia and major
bleeding events . -
pubmed
Results showed that , in a dose - dependent manner ,
KCN1 inhibited cell growth and induced cell cycle arrest in
human pancreatic cancer cells in vitro , and showed in vivo anticancer efficacy in
mice bearing
Panc-1 or
Mia Paca-2 tumor xenografts . -
pubmed
This study aimed to characterize in vivo the carotid arterial intima - media thickness ( IMT ) and mechanical properties in
women with
pre - eclampsia by employing a radiofrequency ultrasound technique . -
pubmed
METHODS : We included 22 late - onset pre -
eclamptic pregnant
women and 28 normotensive pregnant
women who were matched for age ( 29 + - 6 vs. 27 + - 3 , P=0.09 ) and gestational age ( 36.0 + - 3.2 vs. 35.8 + - 2.4 weeks , P=0.802 ) . -
pubmed
The pre -
eclamptic women had a significantly higher arterial pressure than did the normotensive
women ( P<0.0001 ) . -
pubmed
At follow - up examination 18 months after parturition , measurements were repeated in 10 of the pre -
eclamptic women and 11 of the normotensive
women . -
pubmed
Effects of the serotonergic agonist
mCPP on male
rats in the
quinpirole sensitization model of
obsessive - compulsive disorder (
OCD ) . -
pubmed
RATIONALE : The serotonergic agonist ,
meta - chlorophenylpiperazine (
mCPP ) , produces inconsistent effects on
obsessive - compulsive disorder (
OCD ) symptoms , perhaps because clinical studies have not utilized a homogenous
OCD subgroup of
patients . -
pubmed
OBJECTIVES : This study aimed to evaluate
mCPP effects on functional components of compulsive checking , using the
quinpirole sensitization
rat model of
OCD . -
pubmed
METHODS : In study 1 , the effects of
mCPP were evaluated in
quinpirole rats with
compulsive checking . -
pubmed
In study 2 ,
mCPP ( 0 , 0.3125 , 0.625 , and 1.25 mg / kg ) was administered repeatedly to naive
rats and induction of
compulsive checking evaluated . -
pubmed
In naive
rats ,
mCPP did not induce
compulsive behavior , but the highest dose reduced vigor of checking performance compared to saline controls . -
pubmed
Lung and intestine : a specific link in an
ulcerative colitis rat model . -
pubmed
To investigate the link and mechanisms between intestine and lung in the
ulcerative colitis (
UC )
rat model . -
pubmed
Our study is the first to demonstrate the close association between the large intestine and lung in the immune - TNBS -
ethanol - induced
UC rat model . -
pubmed
OBJECTIVE : To analyze the clinical features , diagnosis and treatment of
thrombotic thrombocytopenic purpura (
TTP ) in
patients with
systemic lupus erythematosus (
SLE ) . -
pubmed
METHODS : Clinical manifestations , laboratory findings , diagnosis , treatment and prognosis of 14
SLE patients with
TTP were retrospectively analyzed . -
pubmed
RESULT : Of the 14
patients diagnosed with
SLE and
TTP , 4 were men and 10 were women . -
pubmed
In five
patients , the onset of
SLE preceded
TTP , and in nine
patients SLE and
TTP occurred simultaneously . -
pubmed
All the 14
patients had
thrombocytopenia and
hemolytic anemia , 12 had
fever , 11 had
neurologic abnormalities , and 11 had
renal dysfunction . -
pubmed
The
renal damage in
patients of co - existing diseases is more serious than those with
TTP alone or
SLE alone . -
pubmed
Early diagnosis and prompt treatment with plasma exchange and
steroids may improve the prognosis in
SLE patients with
TTP . -
pubmed
,
peanut ) ,
insect stings , and several medications . -
pubmed
Histologic study of a
human immature permanent premolar with chronic apical
abscess after revascularization / revitalization . -
pubmed
CONCLUSIONS : The presence of a dedicated
osteoporosis health professional coordinating a targeted intervention for
outpatients with low
trauma non -
hip fracture improves investigation and management of
osteoporosis , resulting in the potential for future
fracture prevention . -
pubmed
Cephalic arch stenosis in dialysis
patients : review of clinical relevance , anatomy , current theories on etiology and management . -
pubmed
PARTICIPANTS :
Patients with
chronic pain of at least 6 months , and age 18 years or older . -
pubmed
BACKGROUND : Surgery followed by radiotherapy ( RT ) is indicated for
patients with high - risk
oral cavity cancer (
OCC ) . -
pubmed
Thirty - two
patients ( 78 % ) remained disease - free , 6 ( 15 % ) developed locoregional
recurrence ( 4 in - field , 1 marginal , and 1 out - field ) and 4 ( 10 % ) developed distant
metastasis . -
pubmed
Vancomycin - associated
acute kidney injury in pediatric cardiac intensive care
patients . -
pubmed
OBJECTIVE :
Acute kidney injury (
AKI ) is a significant source of morbidity among critically ill pediatric
patients , including those that have undergone cardiac surgery . -
pubmed
Vancomycin may contribute to
AKI in pediatric
patients admitted to a cardiac intensive care unit . -
pubmed
Patient demographic and disease state variables ,
vancomycin therapy variables , and use of other
nephrotoxic medications were collected . -
pubmed
Patients who developed
vAKI were matched with three patients who did not develop
vAKI , and conditional logistic regression was used to determine independent risk factors for
vAKI . -
pubmed
Vancomycin - associated
AKI occurred in 30
patients ( 7.2 % ) , which resulted in a total of 120
patients ( 30 cases ; 90 controls ) . -
pubmed
BACKGROUND : Less than two percent of the
human genome is protein coding , yet that small fraction harbours the majority of known
disease causing mutations . -
pubmed
Visceral leishmaniasis (
VL ) , also known as kala - azar , is a
disseminated protozoan infection caused by
Leishmania donovani complex . -
pubmed
In conclusion , the findings of this study supports the use of PCR on archive cytological preparation stained slides for the diagnosis of canine
visceral leishmaniasis , emphasizing the higher sensitivity of this technique when compared to direct microscopic examination and mostly the use of the suspect status for the cytology samples that presents the previously mentioned particularities with focus on detecting the oligosymptomatic or assymptomatic
dogs in endemic areas functioning as potential reservoirs for this disease . -
pubmed
Field trial of
Xanthomonas wilt disease - resistant
bananas in East Africa . -
pubmed
BACKGROUND : Patients living with
HIV (
PLHIV ) are increasingly being affected by
cancer . -
pubmed
However , data evaluating the long - term impact of
cancer treatment on
HIV course are sparse . -
pubmed
Adult
PLHIV treated for haematological or solid
malignancies were included and compared ( 1:1 ) with suitably matched (
cancer - free ) controls . -
pubmed
RESULTS : One - hundred - and - ten
patients with
cancer and 110 controls were followed for a median of 4.4 years . -
pubmed
Misregulation of autophagy is likely involved in numerous
human pathologies including aging ,
cancer ,
infections and neurodegeneration , so its biomedical relevance explains the still growing interest in this field . -
pubmed
Ability of obstacle crossing is not associated with falls in independent ambulatory
patients with
spinal cord injury . -
pubmed
OBJECTIVE : To investigate the relationship between ability of obstacle crossing and falls in independent ambulatory
participants with
spinal cord injury (
SCI ) . -
pubmed
METHODS : Ninety - four
participants were evaluated for their
SCI characteristics , ability of walking over small obstacles and functional ability relating to dynamic balance control , lower - extremity motor strength ( LEMS ) and walking ability . -
pubmed
The
CAD genotypes had no effect on the relative content of cellulose and lignin in stalks ofdiploid
wheat and insignificantly influenced the ratio of H : G : S units in the lignin structure , as well as some components of extractives . -
pubmed
OBJECTIVE : To investigate the associations between
obesity and any significant improvements in glycemic control , blood pressure , and lipid targets in Chinese
patients with concomitant
type 2 diabetes mellitus (
T2DM ) and
hypertension . -
pubmed
METHODS AND RESULTS : A total of 3041
dyslipidemia patients with an average age of 65.7 + - 10.53 years and comorbid conditions of
T2DM and
hypertension from the
DYSlipidemia International Study ( DYSIS ) - China were included in the present subgroup analysis . -
pubmed
AREAS COVERED : This article reviews the chemical structure , mechanisms of action , pharmacodynamic and pharmacokinetic properties , as well as clinical applications of small molecules in the treatment of elderly
patients with
B - cell hematological malignancies . -
pubmed
Pharmacokinetic profiles of these agents as well as dosage used and adverse events in
patients with
lymphoid malignancies have been established . -
pubmed
Some of these inhibitors satisfy therapeutic modalities as suitable for the elderly
patients , including those with
chronic lymphocytic leukemia and
non - Hodgkin ' s lymphoma . -
pubmed
METHODS : The SOLVE study was a 24 - week observational study on the initiation of IDet OD in
T2DM patients with uncontrolled
hyperglycemia on diet , exercise , and one or more OADs . -
pubmed
Body weight tended to decrease in
patients from all groups , however , only that in the 2 - OAD group reached statistically significance . -
pubmed
CONCLUSION : Initiation of IDet OD was effective and well - tolerated in Chinese
patients with
T2DM whose glycemia was poorly controlled on OADs irrespective of the number of OADs taken before . -
pubmed
Assessment of operative treatment of
patients with
tertiary hyperparathyroidism after kidney transplantation . -
pubmed
INTRODUCTION : The purpose of the study was to assess the results of operative treatment of
patients with
tertiary hyperparathyroidism (
tHPT ) after kidney transplantation . -
pubmed
MATERIAL AND METHODS : The study included 30
patients in whom kidney transplantation was performed between 2006 and 2013 , and in whom parathyroidectomy had to be performed at a later time because of
tHPT . -
pubmed
Histopathological examination showed one parathyroid
adenoma in six ( 20 % )
patients , and one parathyroid
adenoma and
hyperplasia of the remaining glands in one ( 3.3 % )
patient . -
pubmed
Five ( 16.7 % )
patients had
hyperplasia of two parathyroid glands whereas no changes were observed in two
patients . -
pubmed
On the other hand ,
hyperplasia of all glands was noted in 18 ( 60 % )
patients . -
pubmed
CONCLUSIONS : Surgical resection of parathyroid glands is a management of choice in
patients after kidney transplantation accompanied by
hypercalcaemia lasting longer than one year . -
pubmed
Resection of 3 3/4 parathyroid glands because of
hyperplasia in
patients with
hyperparathyroidism after kidney transplantation enables restoration of normal
calcium metabolism . -
pubmed
OBJECTIVES : To analyze the acute effects of isolated and simultaneous application of whole - body vibration ( WBV ) and electromyostimulation ( ES ) on popliteal artery blood velocity ( BV ) and skin temperature ( ST ) of the calf in
subjects with
spinal cord injury (
SCI ) . -
pubmed
METHODS : Ten
subjects with
SCI were assessed in five different sessions . -
pubmed
This study provides an efficient therapeutic methodology to improve peripheral arterial properties , which is pivotal in
SCI patient 's rehabilitation . -
pubmed
PURPOSE OF THE STUDY : We present the results of a prospective study of
patients with symptomatic partial
ACL tears comparing the pre - operative findings with the clinical results at two years after anterior cruciate ligament ( ACL ) augmentation . -
pubmed
Graft failure was reported in one
patient ( 5.6 % ) and 14 subjects ( 77.8 % ) reported return to pre -
injury sports activities . -
pubmed
Three recent clinical trials on the pharmacologic treatment of
idiopathic pulmonary fibrosis (
IPF ) mark a new chapter in the management of
patients suffering from this very severe
fibrotic lung disease . -
pubmed
A better understanding of the molecular mechanisms of
IPF as well as relevant preclinical tests including
animal models and in vitro experiments on
human lung cells are needed to promote the development of therapeutic drugs . -
pubmed
KEY FINDINGS : These products have relevant
cytotoxicity at a 10 muM concentration and it was also demonstrated for the first time that
H. - pubmed
Detection of
Helicobacter felis in a
cat with
gastric disease in laboratory
animal facility . -
pubmed
A 3 - month - old male
cat in the
animal facility was presented for investigation of
anorexia and occasional
vomiting . -
pubmed
felis - induced
gastroenteric disease in
cat and may provide a valuable data on the study of feline
Helicobacter infection . -
pubmed
MATERIAL AND METHOD : A total of 390
patients who underwent surgery to treat
anterior shoulder instability between March 2013 and June 2014 were included and divided into three groups depending on whether they were managed using open surgery with screw fixation , arthroscopy with screw fixation , or arthroscopy with endobutton fixation . -
pubmed
Here we describe a
mouse model of
DIPG in which H3K27 M potentiates
tumorigenesis . -
pubmed
The most interesting advances have been incorporating orthodontic procedures in conjunction with myofunctional therapy in prepubertal
children , raising the possibility of
OSA prevention by initiating treatment early in life . -
pubmed
Promising Effects of Neurorestorative Diets on Motor , Cognitive , and
Gastrointestinal Dysfunction after Symptom Development in a
Mouse Model of
Parkinson ' s Disease . -
pubmed
This is the first study demonstrating beneficial effects of specific dietary interventions , given after full development of symptoms , on a broad spectrum of motor and non - motor symptoms in a
mouse model for
PD . -
pubmed
However , many
patients with
RA fail to respond to this or other biologics , and some patients may suffer unexpected aggravation of
arthritic inflammation or other autoimmune effects . -
pubmed
Molecular epidemiology of
Escherichia coli sequence type 131 and its H30 / H30 - Rx subclones recovered from
extra - intestinal infections : first report of OXA-48 producing ST131 clone from Iran . -
pubmed
Multidrug - resistant ( MDR ) O25b - ST131 clone of
Escherichia coli is well established as a significant cause of
extra - intestinal infections worldwide . -
pubmed
The prevalence of
ST131 was 29.8 % among phylogroups B2 , D , and F of
E.coli isolates recovered from extra - intestinal
infections . -
pubmed
PURPOSES : To establish the in silico ocular pharmacokinetic modeling for eye drops , and to simulate the dose regimen for
FK962 in
human choroid /
retinal diseases . -
pubmed
Neurite elongation by
FK962 was measured in cultured
rat retinal
ganglion cells . -
pubmed
PURPOSE : The case of a
patient who experienced
bone marrow edema and
pain in both feet and a
compression fracture of one heel bone after several months of
everolimus use is reported . -
pubmed
The
patient was referred for orthopedic evaluation , which resulted in diagnosis of
bone marrow edema and a
compression fracture of the calcaneus on the basis of magnetic resonance imaging results . -
pubmed
The case was discussed with a clinical pharmacist , and after an in - depth analysis to rule out potential alternative causes for the
patient 's
edema and
pain ,
everolimus was discontinued . -
pubmed
CONCLUSION :
Bone marrow edema developed and a
fracture occurred in a
patient taking
everolimus for a
metastatic pNET , with complete resolution of lower extremity
swelling and
pain within 2 weeks of
everolimus discontinuation . -
pubmed
CONCLUSIONS : Recognition of the imaging manifestations of
fibrodysplasia ossificans progressiva is imperative to early diagnosis in order to appropriately direct
patient care and preclude unnecessary biopsies or surgical procedures . -
pubmed
CONCLUSION : Our analysis indicates that
naproxen can decrease the occurrence of
heterotopic ossification without increasing complications in hip surgery
patients . -
pubmed
It nevertheless represents a major health problem in these
patients , and is associated to life - threatening complications including increasing risk of
cardiovascular pathologies . -
pubmed
METHODS AND FINDINGS : To achieve this , we have first fully characterized the metabolic deregulations in these
patients by conducting a longitudinal retrospective study , in
children with
achondroplasia Anthropometric , densitometric measures as well as several blood parameters were recorded and compared between three age groups ranging from [ 0 - 3 ] , [ 4 - 8 ] and [ 9 - 18 ] years old . -
pubmed
Because it is not associated with
diabetes , the atypical
obesity has not been studied in the past even though it is recognized as a real problem in these
patients . -
pubmed
CONCLUSION : This study demonstrate that
achondroplasia patients develop an atypical
obesity with preferential
abdominal obesity not associated with classical complications . -
pubmed
These data strongly suggest that this common complication of
achondroplasia should be included in the clinical management of
patients . -
pubmed
RESULTS :
Orthostatic hypotension was present , depending on applied definition , in 34.5 % of the
individuals at 1 min , 38.3 % at 3 min ; 44.9 % on either 1 or 3 min , and 27.8 % individuals in both measurements . -
pubmed
In the second case , a
patient with a
pancreatic head adenocarcinoma with duodenal invasion that precluded major papillae identification was submitted to a choledochoduodenostomy . -
pubmed
The tri - axial acceleration signals were converted into 2D acceleration images and a Convolutional Neural Network ( CNN ) was trained to recognize the differences between non - medicated
ADHD children and their paired controls . -
pubmed
Hip involvement in
patients with
calcium pyrophosphate deposition disease : potential and limits of musculoskeletal ultrasound . -
pubmed
DESIGN : Fifty consecutive
patients with " definite "
CPPD and 40 age / sex /
body mass index - matched disease controls who had undergone hip CR within the previous six months were enrolled . -
pubmed
After their entrance , CNTs reach the CNS where they may cause
cytotoxicity of selected neurons in several CNS regions , impairing molecular pathways and contributing to the onset and progression of
chronic brain inflammation , microglia activation and
white matter abnormalities with an increased risk for
autism spectrum disorders , lower IQ in
children ,
neurodegenerative diseases and
stroke . -
pubmed
Indigofera oblongifolia protects against
trypanosomiasis - induced spleen injury . -
pubmed
BACKGROUND :
Trypanosomiasis is a
neglected tropical disease , transmitted by blood - sucking insects and can affect
humans and animals , depending on the species of
Trypanosoma parasite . -
pubmed
Indigofera oblongifolia leaf extract ( IOE ) has been shown to treat blood stage
malaria . -
pubmed
Anemia was apparent during the course of
infection in
T. - pubmed
evansi - induced
spleen injury in
mice . -
pubmed
This study aimed to test the correlation of functional outcome in
patients with
pelvic fractures with the postoperative radiographic quality of reduction . -
pubmed
METHODS : Consecutive
patients with an isolated traumatic
pelvic fracture that required closed or open reduction between 07/2015 and 07/2017 and had a completed follow - up of at least 6 months were included ( N = 31 , mean age 50 years , SD 21 years , range , 16 to 88 years ) . -
pubmed
The 13 - gene - based classifier described in the current study may be used as a potential biomarker to predict the effects of
fluorouracil - based chemotherapy in
patients with
CRC . -
pubmed
Results : A total of 2032
Escherichia coli ( 875
ESBL - producing ) and
Klebsiella pneumoniae ( 157
ESBL - producing )
strains , and 371 other Enterobacteriaceae
strains , were isolated from patients with
bloodstream infections (
BSIs ) . -
pubmed
We herein review alterations in angiogenesis observed in
human and experimental
diabetes and how they contribute to
diabetes onset and development of vascular complications . -
pubmed
In a study of
visual complications following
head trauma , only 4.4 % of
patients suffered from
chiasmal injuries . -
pubmed
We report the one - year follow - up of clinical , visual field , and MRI findings of a
patient with complete transection of the optic chiasm following
head trauma . -
pubmed
This study compared the impact of nano -
ubiquinone (
Nubiq ) with native
ubiquinone (
ubiq ) reducing damage induced by
Paracetamol -
toxicity in
rats . -
pubmed
Systematic analysis of lncRNA expression profiles and
atherosclerosis - associated lncRNA - mRNA network revealing functional lncRNAs in carotid
atherosclerotic rabbit models . -
pubmed
Atherosclerosis was induced in
rabbits ( n = 3 ) carotid arteries via a high - fat diet and
balloon injury , while age - matched
rabbits ( n = 3 ) were treated with normal chow as controls . -
pubmed
We provided an ASLMN of
atherosclerosis development in carotid arteries of
rabbits and probable targets which may lay the foundation for future research of clinical applications . -
pubmed
These include , the multiplex , magnetic bead - based immunodiagnostics for both
Lassa virus antigens and antibodies ; molecular probe - based quantitative real - time PCR for genomic signatures ; rapid diagnostics tests that detects the most prevalent West African lineages ; and the successful utilization of next - generation sequencing technology to diagnose and characterize
Lassa virus in West Africa . -
pubmed
In conclusion , PV mouth region appear to be a most susceptible to adrenergic
proarrhythmia in
mice . -
pubmed
The
patient with
bronchial asthma had
multiple sclerosis and was treated using
natalizumab . -
pubmed
The
patient was referred to our department because of a persistent
cough . -
pubmed
STUDY DESIGN / MATERIALS AND METHODS :
Patients with eyebrow tattoos underwent treatment with dual - wavelength picosecond Nd : YAG laser at 1,064 - nm with a 3 mm
spot size and fluence of 4 - 4.6 J / cm2 . -
pubmed
PLA modification significantly improved the cytocompatibility of
PEI ,
PEI -
PLA copolymer showed much higher cell viability than
PEI as verified in three different
human cancer cell lines (
HCT116 ,
HepG2 and
SKOV3 ) . -
pubmed
CASE REPORTS : Our three cases are representative of
sleep - disordered breathing that occurred as a consequence of VNS activity in
patients with
refractory epilepsy . -
pubmed
Sleep apnoea was observed in two
patients and
stridor in one
patient . -
pubmed
CONCLUSIONS : Given the high prevalence of
sleep apnoea - hypopnoea syndrome in
patients with
refractory epilepsy , implantation of VNS should be ideally preceded by an assessment of the breathing during sleep . -
pubmed
Impact of breed on
canine humeral condylar
fracture configuration , surgical management , and outcome . -
pubmed
OBJECTIVE : To report the prevalence , configuration , risk factors , fixation methods and outcomes after repair of
humeral condylar fractures (
HCF ) in
dogs . -
pubmed
METHODS : Medical records of
dogs referred between January 2010 and August 2018 were searched for
HCF . -
pubmed
RESULTS :
Dogs with
HCF represented 112 of 43 325 ( 0.26 % , 95 % CI 0.22 - 0.31 ) referrals . -
pubmed
Lameness was scored as 1 of 5 ( median ) in the 85
dogs with initial follow - up ( median 6 weeks ) after HCF repair . -
pubmed
CONCLUSION : French bulldogs and
spaniels were predisposed to
HCF , and medial
HCF were more common in French bulldogs . -
pubmed
Preeclampsia is a potentially life - threatening
multisystem disease affecting 4 % to 8 % of pregnant
women after the 20th week of gestation . -
pubmed
Patients ' sex , age , comorbidities , anatomic location of the
wound , and the indications for ciNPWT were recorded . -
pubmed
Late - term
seroma and
hematoma formation were encountered in two
patients . -
pubmed
Indications for ciNPWT utilization were preventing
dehiscence ,
seroma , and
hematoma formation in the majority of the
patients . -
pubmed
The relevance of the ectoparasitic mite
Varroa destructor acting as mechanical and biological virus vector for the enhanced virulence of certain viruses or mite selected virus
strains is carefully considered . -
pubmed
The combination of endoscopic molecular imaging and photoimmunotherapy used in initial treatment may avoid the need of repeat transurethral resection in strictly selected
patients and improve oncological outcomes such as
recurrence - free survival and overall survival after operation . -
pubmed
Impact of dedicated
infectious disease teamwork on the treatment and prognosis of
patients with
diabetic foot infection . -
pubmed
More
human deaths have been attributable to
Mycobacterium tuberculosis than any other pathogen , and the epidemic is sustained by ongoing transmission . -
pubmed
A Blood - based Gene - expression Scoring System for
Cancer Screening in
Patients With
Branch - duct Intraductal Papillary Mucinous Neoplasms . -
pubmed
BACKGROUND : In
patients with
branch - duct intraductal papillary mucinous neoplasms (
BD - IPMN ) , we aimed to develop a novel blood - based biomarker utilizing a gene - expression profile for the detection of
pancreatic malignancies , such as
IPMN - derived
carcinoma (
IPMC ) or
pancreatic ductal adenocarcinoma (
PDAC ) . -
pubmed
PATIENTS AND METHODS : We enrolled 40
patients with pancreatic
tumors ( 24 BD -
IPMNs , four
IPMCs and 12
PDACs ) and identified the characteristic gene - expression profiles in
pancreatic malignancies . -
pubmed
The result was validated in 14
patients ( five
IPMNs , three
IPMCs and six
PDACs ) . -
pubmed
CONCLUSION : We developed a blood - based gene expression scoring system for
cancer screening in
patients with
BD - IPMNs . -
pubmed
Application of an iris speculum for removing Soemmerring ring during secondary intraocular lens implantation in
congenital cataract patients with
small pupils . -
pubmed
An application of the XpandNT iris speculum in eyes with
small pupils during secondary intraocular lens ( IOL ) implantation in
congenital cataract patients is described . -
pubmed
Fourteen aphakic eyes from 10 consecutive
patients were studied retrospectively ; pupil expansion was achieved in all 14 eyes intraoperatively without serious intraoperative or
postoperative complications . -
pubmed
The XpandNT iris speculum was a safe and excellent tool for removing Soemmerring ring and solving
small pupil problems during secondary IOL implantation in pediatric
cataract surgery
patients . -
pubmed
Altered gene expression profile of
Wolbachia pipientis wAlbB
strain following transinfection from its native host
Aedes albopictus to
Aedes aegypti cells . -
pubmed
The
Aedes albopictus - derived
strain wAlbB is promising in this regard . -
pubmed
Patient 's demographic features , pre - operative
signs and symptoms , details of rendered clinical procedures , follow - up visits , clinical and radiographic findings were recorded . -
pubmed
Hepatoma , host liver , and normal
rat liver neutral lipids as affected by diet . -
pubmed
Groups of normal and
hepatoma ( 7288CTC ) bearing
rats were maintained on normal chow and fat - free diets for 4 weeks . -
pubmed
The unchanged high level of essential
fatty acids in the
hepatoma lipids from the fat - free fed
animals demonstrates the
hepatoma 's ability to absorb and conserve specific
fatty acids . -
pubmed
Anatomic , clinical , and digestion analyses were done on 18
human urinary bladder polyps from patients with
Schistosoma haematobium infections . -
pubmed
Because of the high sensitivity and broad - spectrum reactivity , this technique could be useful for studying the pathogenesis and laboratory diagnosis of
inclusion body hepatitis caused by several serotypes of
AAV . -
pubmed
Results of its transplantation on long not - healing donor
wounds in 13
patients after autodermatoplastic operations have been studied . -
pubmed
We studied a family in which one out of two
children presented a non - salt wasting form of
CAH . -
pubmed
Patients with the X - linked type are highly susceptible to
infections ; those with the autosomal recessive form may be less severely affected . -
pubmed
As a step in the understanding of the molecular genetics of this form of
ITP we have determined the nucleotide sequences of expressed V region genes selected from a panel of five
human lymphoblastoid cell lines derived from
patient DM . -
pubmed
In a randomized comparative study , 83 male
patients suffering from acute uncomplicated
gonococcal urethritis were treated with a single dose of either 0.8 g
pefloxacin , given orally , or 1.0 g
cefotaxime , given intramuscularly . -
pubmed
Postgonococcal
urethritis was found in 9 % of the
patients treated with
pefloxacin and in 20 % of the
patients treated with
cefotaxime . -
pubmed
No side effects were recorded in either groups of patients except that 46 % of the
patients treated with
cefotaxime reported mild
pain at the injection site . -
pubmed
Liver tumor promoters and other
mouse liver carcinogens . -
pubmed
Mouse liver tumors are important end points for safety assessment of chemicals in
rodent carcinogenicity assays . -
pubmed
If test
mice have spontaneous
tumors of high or low background incidence , the promotion of these
tumors or of spontaneously initiated or susceptible cells may provide a basis for
carcinogenesis induced by these compounds . -
pubmed
Experimental systems have been developed to study the mechanisms of
tumor promotion in
mouse liver . -
pubmed
These models should significantly advance research into mechanisms of hepatocarcinogenesis and
tumor promotion in
mouse liver and may subsequently be used for
human risk assessment . -
pubmed
Enhanced arrhythmogenicity of
Freon 113 by
hypoxia in the perfused
rat heart . -
pubmed
The interaction of
Freon 113 (
1,1,2 - trichloro-1,2,2 - trifluoroethane ) and
hypoxia on the heart conduction system was studied using electrocardiogram monitoring of isolated perfused
rat hearts . -
pubmed
In the discussion of the responsibilities of society to the
HIV infected and uninfected , a serious question seems to have been left out of the picture : To what extent are people who are not
infected , have no special relationship to the infected and have no professional responsibilities for the care of
AIDS patients under an obligation to come to the aid of people with the
HIV ? -
pubmed
Histological distribution was : follicular small cleaved cells 70
patients , follicular mixed 31
patients , small cells
CLL type 12
patients . -
pubmed
In a study of 54
women admitted to a day - care unit for this procedure , validated measures were utilized to assess the incidence , intensity and duration of
pain after tubal ligation ( McGill
Pain Questionnaire ) and the impact of
pain on the activities of daily living ( Modified Functional Assessment Inventory ) . -
pubmed
In Timm 's sulfide silver preparations , intragranular and supragranular mossy fiber staining is found to be much more prevalent in the temporal dentate gyrus of the spontaneous
epileptic mouse , tottering , than at matching levels in unaffected littermate controls . -
pubmed
In a study of 394 homosexual men recruited at the primary care level the prevalence of antibody to
human T - lymphotropic retrovirus ( HTLV - III ) was higher among those with
lymph node enlargement than among controls . -
pubmed
Correlation between
spiramycin treatment and negative results of
mouse inoculation of placental material suggests that
spiramycin might decrease the risk of materno - fetal transmission of
toxoplasma by reducing the severity and duration of
toxoplasmic placentitis . -
pubmed
The authors report the case of an isolated
supratentorial hemangioblastoma occurring in a
woman operated on for a
cerebellar hemangioblastoma twenty years before . -
pubmed
Acute orthostatic hypotension is a common occurrence during a
patient 's first experiences out of bed after surgery or a period of immobility . -
pubmed
[
Rabies ; epidemiological aspects of animal attacks and frequency reported to the anti -
human rabies service in Araguari , Minas Gerais ] . -
pubmed
Vitrectomy surgery is effective for
diabetic vitreous haemorrhage and traction
retinal detachment , producing improved vision in most
patients , but only a relatively small percentage of
patients so treated recover good visual acuity ( greater than or equal to 6/12 ) . -
pubmed
The primary care physician who deals with diabetic
patients should be familiar with the lesions of
diabetic retinopathy and with current therapeutic modalities . -
pubmed
He should perform an examination of the posterior retina with the direct ophthalmoscope on each
diabetic patient at each visit , and should institute prompt referral to an ophthalmologist at the first sign of change . -
pubmed
Periodic examination of all
diabetic patients by an ophthalmologist should be conducted at the intervals recommended in the previous section . -
pubmed
Both combination drugs have similar serum half - life values in
persons with normal renal function ( half - life of 8 to 12 hours ) , but the
sulphamethoxazole metabolites are retained more than
trimethoprim in
reduced renal function . -
pubmed
One hundred eleven
patients were treated for
upper extremity complications due to therapeutic agents . -
pubmed
One
patient had a persistently raised free T4 concentration and was considered to be
thyrotoxic . -
pubmed
Experimental development of a
cambendazole - resistant
strain of
Haemonchus contortus in
sheep . -
pubmed
[
Sodium and
potassium in serum and sputum of
patients with
bronchial asthma ] . -
pubmed
[
Acute pericarditis in
children ] . -
pubmed
Pulmonary parenchymal defects in
dogs following prolonged cigarette smoke exposure . -
pubmed
Goodson and Hunt showed that
wound healing is impaired in
streptozotocin ( Sz )
diabetic rats ; we speculated that this impairment results from defective early inflammatory responses to wounding . -
pubmed
Because we had shown that supplemental
vitamin A stimulates the early inflammatory response to wounding in nondiabetic
rats , we studied the effect of supplemental
vitamin A on
wound healing in
rats with Sz - induced
diabetes . -
pubmed
Two - thirds of the
rats were injected ( intravenously ) with Sz 60 mg / kg
body weight . -
pubmed
All of these
rats became
diabetic (
hyperglycemia greater than 350 mg / dl ,
hyperphagic , polydipsic ,
polyuric , glycosuric greater than 2 % ) . -
pubmed
The
wounds of
Group 2 rats healed poorly compared to Group 1 ( breaking strength of skin incisions , 308 + /- 19 g vs 584 + /- 23 g , p less than 0.001 ;
hydroxyproline of the sponge reparative tissue , 0.87 mg vs 2.40 mg/100 mg sponge p less than 0.001 ) . -
pubmed
Supplemental
vitamin A ( Group 3 ) did not affect the
hyperglycemia ,
hyperphagia ,
polydipsia or
glycosuria , but increased the breaking strengths of the incisions of the
diabetic rats ( 468 + /- 40 g , p less than 0.001 ) , and the sponge
hydroxyproline ( 2.38 mg/100 mg sponge , p less than 0.001 ) . -
pubmed
The action of supplemental
vitamin A in correcting the impaired
wound healing ,
adrenal enlargement , thymic involution and
lymphocytopenia of Sz -
diabetic rats is independent of an effect on their disturbed
carbohydrate metabolism . -
pubmed
Fibroma in a
Nine - banded armadillo (
Dasypus novemcinctus ) . -
pubmed
An adult male
Nine - banded armadillo (
Dasypus nonemcintus ) had a large
tumour between the first and second phalanges of the right fore - foot . -
pubmed
Diagnostic and prognostic significance of total
bile acids concentrations has been evaluated in 26
patients with
acute viral hepatitis . -
pubmed
A remarkable rise in serum
bile acids concentration has been showed in acute stage of
hepatitis ; the level of
cholates is significantly higher in
cholangitic jaundice , but difference is not found in respect of
patients with
extrahepatic cholestasis . -
pubmed
A
patient is presented who had severe
headache and then developed a stuttering course of clinical
neurological deficits . -
pubmed
A prospective review of 272 institutionalized
cerebral palsy residents was undertaken in order to determine the incidence and characteristics of
neuromuscular scoliosis in this population . -
pubmed
The
mouse MXT mammary and the
human J82 and
T24 bladder tumor cell lines were used in this study . -
pubmed
A
patient with navel
metastasis from
ovarian carcinoma was treated by immunotherapy and neo - adjuvant intraarterial infusion chemotherapy ( OK-432 i.c . -
pubmed
There were two
patients with
adrenoleukodystrophy , four with
dentato - rubro - pallido - luysian atrophy , three with
familial spastic paraplegia , two with
myotonic dystrophy and three with
dementia of unknown origin . -
pubmed
Selection for eight - week
body weight in two randombred
chicken populations under altered water to feed ratios . -
pubmed
However such
patients are usually at greater risk from systemic
relapse . -
pubmed
Tabulations and expectations regarding the genetics of
human hypertension . -
pubmed
Results from family studies suggest several possible single gene traits may be related to essential
hypertension in
humans . -
pubmed
Eight genetic loci ( on chromosomes 1 , 6 , 8 , 17 and 19 ) are possibly related to essential
hypertension in
humans and are also reviewed . -
pubmed
The study objective was to identify prognostic factors associated with survival in
patients treated for
acute leukemias who developed
invasive aspergillosis (
IA ) during induction therapy . -
pubmed
There was no statistical difference between the
patients who survived and those who died in relation to the mean time of onset of
IA or the total and mean daily dose of
amphotericin B. -
pubmed
On the other hand a favourable outcome correlated strongly with complete leukemic remission ( p & lt ; 0.0001 ): all but one of the
patients with objective residual
leukemia died of
IA , whereas all those who achieved complete hematological remission survived . -
pubmed
In conclusion , it seems that the main vital prognostic factor in these
leukemic patients with IA was the achievement of complete remission . -
pubmed
We were unable to control IA in 10 of 11
patients with
refractory leukemia , regardless of
neutropenic status , despite early administration of high - dose
amphotericin B. -
pubmed
[ Noninvasive ventilator support in
patients with
chronic obstructive pulmonary disease . -
pubmed
Three hundred and eighty - one consecutive
patients referred to our Nuclear Medicine Service from the Cardiology Department during a period of two years have been studied to evaluate
Coronary Artery Disease (
CAP ) using
99mTc - MIBI single photon emission computed tomography ( SPECT ) . -
pubmed
The sensitivity and specificity for detecting
CAD in the whole group of
patients , referred ( n = 161 ) or not ( n = 220 ) for coronary angiography , were calculated following Diamond 's method , and were found to be 87 % and 92 % , respectively . -
pubmed
The ] purpose of this report is to describe three
patients with
levonorgestrel implants ( Norplant system ) who developed
TTP . -
pubmed
CASES : A 24 - year - old
woman with
levonorgestrel implants in place for 7 months was admitted to our hospital for treatment of
TTP . -
pubmed
In this paper , four
patients with
gyrate atrophy are described . -
pubmed
All
patients had
visual impairment ,
mental retardation ,
hyperornithinemia ,
hypolysinemia ,
ornithinuria and
lysinuria . -
pubmed
It is suggested that
gyrate atrophy must be considered in all
patients with
chorioretinal atrophy . -
pubmed
Effect of
thyroid deficiency on Go alpha - subunit isoforms in developing
rat cerebral cortex . -
pubmed
Serial undiluted passages were performed with the PUR46
strain of
TGEV in
swine testis ( ST ) cells . -
pubmed
Coronal suture pathology and
synostotic progression in
rabbits with
congenital craniosynostosis . -
pubmed
The purpose of the present study was to describe coronal suture pathology and cross sectional synostotic progression in an inbred
strain of
rabbits with
congenital craniosynostosis . -
pubmed
Findings demonstrate that
coronal suture synostosis in the congenital
rabbit model ( 1 ) begins early during suture morphogenesis ( before 25 days of gestation ) ; ( 2 ) consistently radiates from a single focus corresponding to a normal interdigitating region ( i.e. -
pubmed
Of the 108
cases , 96 had age - related
macular degeneration , 6 had
angioid streaks and 3 had
degenerative myopia . -
pubmed
Right internal carotid arteries of 36
rabbits were embolized using aged heterologous
thrombi . -
pubmed
RESULTS :
Patients who underwent definitive surgery for
breast cancer in the follicular phase had a slightly worse
disease - free survival than those operated on during the luteal phase ( five - year DFS percentage : 53 % versus 58 % ; hazard ratio , 1.13 ; 95 % confidence interval ( CI ) , 0.94 - 1.38 ; P = 0.20 ) . -
pubmed
The effect was significantly greater for the subpopulation of 300
patients with
ER - negative primaries ( P = 0.02 interaction effect ; five - year DFS percentages 42 % vs. 59 % ; hazard ratio 1.60 ; 95 % CI , 1.12 - 2.25 ; P = 0.008 ) . -
pubmed
Hyperinsulinemia in non - obese , non - diabetic
subjects with isolated
systolic hypertension . -
pubmed
31 ( 91 % ) procedures were carried out without complications ; there was a false
aneurysm in 1 patient ( 3 % ) and an occlusion of the brachial artery at the puncture site in 2
patients ( 6 % ) . -
pubmed
The occluded vessels of two
diabetic women had a reduced diameter at the level of 10 % of the standard distribution and an unfavorable ratio of sheat - to - vessel - diameter which lead initially to an obstruction of nearly 50 % of the vessel lumen during catheterization . -
pubmed
Tono - Pen determination of intraocular pressure in
patients with
band keratopathy or
glued cornea . -
pubmed
AIMS : To evaluate the intraocular pressure ( IOP ) measurements in
patients with
band keratopathy or glued corneas obtained from affected and non - affected areas . -
pubmed
METHODS : 15
patients with
band keratopathy or glued corneas were prospectively recruited . -
pubmed
RESULTS : Determination of IOP with the Tono - Pen was possible in all cases , while Goldmann tonometry was not performed in three
patients because of severe
corneal irregularities . -
pubmed
CONCLUSION : In
patients with
band keratopathy or glued corneas determination of IOP by Tono - Pen tonometry varies from affected to non - affected area . -
pubmed
Six of the 66
patients had malignant
tumors . -
pubmed
Coumarin skin necrosis occurs almost exclusively in
patients with
venous thrombosis between the 3rd and 10th day after beginning anticoagulation . -
pubmed
CONCLUSION : Peritoneal scintigraphy is useful in the evaluation and assessment of
CPD patients who develop anatomical problems ( such as anterior abdominal , pleural - peritoneal , inguinal , and genital leaks ) and problems with ultrafiltration and/or drainage . -
pubmed
Reports on 68
patients with
DNH were obtained . -
pubmed
Reports on 64
patients with
neonatal haemangiomatosis limited to only the skin and liver were also obtained . -
pubmed
The clinical features and outcome of
patients with only
cutaneous and hepatic haemangiomas were similar to those of
patients with
DNH . -
pubmed
The inclusion criteria for DNH should be expanded to include similar
patients with only
cutaneous and hepatic haemangiomas . -
pubmed
These data indicate that
strains commonly classified as
Streptococcus thermophilus may belong to different taxa . -
pubmed
, all these
strains indeed belong to the same species ,
Lactococcus lactis . -
pubmed
Previously , we have reported that
L - deprenyl decreased the incidence of
mammary tumors and
pituitary tumors in old acyclic
rats . -
pubmed
Female
Sprague - Dawley rats with
DMBA - induced
mammary tumors were injected ( sc ) daily with 0.25 mg or 5.0 mg of
deprenyl / kg BW or the vehicle ( saline ; control ) for 12 wk . -
pubmed
The prevalence of
Chlamydia pneumoniae antibodies in Thai patients with
coronary artery disease . -
pubmed
Blood samples were obtained from 243 consecutive
coronary artery disease (
CAD )
patients ( 177 male , 66 female ) aged 35 - 78 years ( mean , 61 years ) admitted for coronary angiography because of suspected
coronary heart disease , and from 115 blood donors ( 91 male , 24 female ) aged 25 - 60 years ( mean , 47 years ) . -
pubmed
thompsoni
strain HnC are active against the
codling moth ,
Cydia pomonella , a major pest of orchards . -
pubmed
Medullary thyroid carcinoma was found in 7
patients ( aged 5 - 56 years ) ,
C - cell hyperplasia in 6
patients ( aged 13 - 40 years ) , and normal histology in a single
patient ( aged 27 years ) . -
pubmed
One
patient with
medullary thyroid carcinoma died of
metastases ( aged 12 years ) . -
pubmed
The week prevalence of back and
neck pain was evaluated at these test moments in extended samples of intervention
children ( n = 347 ) and controls ( n = 349 ) . -
pubmed
The aim of the present study was to investigate the pharmacokinetics of
oestriol in plasma in the
dog after repeated oral administration of
oestriol tablets , a preparation intended for the treatment of
urinary incontinence in the bitch . -
pubmed
Adverse drug events among elderly
outpatients are common and preventable . -
pubmed
Experiments were performed using
HT-22 , an immortalized
mouse hippocampal cell line , and
SK - N - SH , a
human neuroblastoma cell line . -
pubmed
[ Effect of drugs on the temporal sphygmogram in
humans and its significance in experimental
headache ] . -
pubmed
[ Research on the electrophoretic fractionation of the serum of
patients with
gouty arthropathies ] . -
pubmed
Diagnostic coronary angiography induces a systemic inflammatory response in
patients with
stable angina . -
pubmed
The aim of this study was the determine whether diagnostic coronary angiography performed in
patients with
stable angina triggers a systemic inflammatory response . -
pubmed
METHODS : We prospectively studied
patients with
chronic stable angina undergoing either coronary angiography ( n = 13 ) or coronary angiography followed by PCI ( n = 13 ) . -
pubmed
Patients with periprocedural
myocardial necrosis were excluded . -
pubmed
CONCLUSION : Uncomplicated diagnostic coronary angiography triggers a systemic inflammatory response in
patients with
stable angina . -
pubmed
METHODS : Seventy eyes of 35
patients with
rhegmatogenous retinal detachments were included in this study . -
pubmed
None of the
patients had pathologic
myopia or a history of ocular surgery . -
pubmed
Consistent with this hypothesis , we detected increased hypothalamic Mch mRNA levels in agouti ( Ay )
mice ( by 102 % ; P & lt ; 0.05 ) , a model of genetic
obesity resulting from impaired melanocortin signaling , compared to wild - type controls . -
pubmed
We therefore investigated the effects of energy restriction on hypothalamic Mch gene expression in both Ay
mice and in wild - type
mice with diet - induced
obesity ( DIO ) . -
pubmed
Determination of
relapse risk based on assessment of
minimal residual disease during complete remission by multiparameter flow cytometry in unselected
patients with
acute myeloid leukemia . -
pubmed
Quantification of
minimal residual disease ( MRD ) reveals significant prognostic information in
patients treated for
acute myeloid leukemia (
AML ) . -
pubmed
DNA - DNA pairing studies showed that the unidentified organism displayed more than 70 % relatedness to the type
strains of
S. - pubmed
On the basis of phenotypic and molecular genetic evidence , it is proposed that the unknown
Streptococcus isolates from ovine and caprine
mastitis be classified as a novel subspecies ,
Streptococcus equi subsp . - pubmed
The type
strain is
CECT 5772(T ) (= CCUG 47520(T)=Mt 167(T ) ) . -
pubmed
ni High 5 cells were permissive to
ThorMNPV in terms of
infection and viral DNA transfection , but SF-21 was less permissive and the
infection process was slower . -
pubmed
This case highlights the difficulties encountered in assessing
patients with superior premorbid function in the early stages of
Alzheimer ' s disease , and reveals the value of serial MRI and neuropsychological assessment in detecting and monitoring early
neurodegenerative disease . -
pubmed
MATERIALS AND METHODS : 137 serum and whole blood samples collected from 31
ovarian cancer patients during their consecutive hospital stays . -
pubmed
Thrombocytosis occurred in 45 %
patients before treatment , and in none when the 6th course of chemotherapy was given . -
pubmed
EXPERIMENTAL DESIGN :
Human pancreatic cancer cells were injected into the pancreas of
severe combined immunodeficient mice . -
pubmed
A delicate balance between normalization and excessive regression of
tumor vasculature is important when initiating alternative combinatorial regimens for treatment of
patients with
pancreatic cancer . -
pubmed
Chronic bronchitis is the most frequent late
respiratory disease among
Iranians exposed to mustard gas during the Iraq - Iran war . -
pubmed
The aim of this study was to investigate efficacy of oral and intravenous
corticosteroid therapy in improving lung function in mustard gas induced
chronic bronchitis patients . -
pubmed
65 mustard gas - exposed
chronic bronchitis patients , who were not responsive to standard treatments in exacerbation occasions , were randomly divided into two groups : an intravenous group ( 39
patients ) receiving 500 mg intravenous
methylprednisolone daily , and an oral group ( 26
patients ) receiving 1 mg / kg oral
prednisolone daily . -
pubmed
Since short - term
corticosteroid therapy has a significant effect on lung function of almost fifty percent of
patients with mustard gas - induced
chronic bronchitis in exacerbation occasions , we suggest a short - term bolus
steroid treatment to triage the
patients into responders and non - responders for subsequent treatment . -
pubmed
Mental dysfunction of 130
children aged 0 - 14 years with a history of
family physical abuse was studied using a number of known methods adapted for early aged children including an original scale of
mental dysfunction assessment , which has been elaborated in Mental Health Research Center ( Moscow ) . -
pubmed
PURPOSE : The purpose of this research was to evaluate
pain and
anxiety levels in
patients undergoing chemotherapy via central venous catheter ( CVC ) and peripheral venous access ( PVA ) . -
pubmed
METHOD : The sample consisted of 56
cancer patients undergoing at least one chemotherapy treatment cycle . -
pubmed
They were divided into two groups based on the administration method of the chemotherapeutic drug : the experimental group (
patients with
CVC ) and the control group (
patients with PVA ) . -
pubmed
Three isolates of
Infectious bursal disease virus (
IBDV ) , designated UPM04178 , UPM04190 and UPM04238 , were obtained from severe outbreaks of
infectious bursal disease (
IBD ) in Malaysia in 2004 . -
pubmed
Phylogenetic analysis revealed clustering of the three isolates with
vvIBDV strains . -
pubmed
Evolutionary relatedness of the three isolates to
vvIBDV strains was demonstrated by three phylogenetic methods : bootstrap values of 100 % , 95 % and 90 % for nucleotide sequences and those of 58 % , 86 % and 96 % for
amino acid sequences were obtained by the distance , maximum parsimony and maximum likehood methods , respectively . -
pubmed
Trough serum concentrations of
infliximab were measured in 6 adult
patients with various diseases and in 5 pediatric
patients with
Crohn ' s disease . -
pubmed
Twenty
patients undergoing emergency Caesarean section with spinal anesthesia ( spinal group ) were also investigated to confirm that epidural block is effective for
postoperative pain . -
pubmed
Discontinuation of
tamsulosin treatment in
men with
lower urinary tract symptoms : a pilot study . -
pubmed
OBJECTIVES : Since little investigation has been undertaken to determine if alpha1 - blockers should be given continuously to sustain their efficacy , we conducted a pilot study to determine symptom change following discontinuation of
tamsulosin after an initial improvement in symptoms in
men with
lower urinary tract symptoms (
LUTS ) . -
pubmed
PATIENTS AND METHODS : Thirty - three of 78
patients with mild - to - moderate
prostate hyperplasia , who had symptom improvement according to the International Prostate Symptom Score ( IPSS ) to & lt;10 or the quality of life ( QOL ) index to & lt ; or =3 after initial treatment with
tamsulosin , were enrolled in this study . -
pubmed
METHODS : A prospective study of 100 unrelated blood donors and 121 consecutive
patients with
AAU was carried out . -
pubmed
Radiological examination of the sacroiliac joints was conducted in
patients with
low back pain or
arthralgias . -
pubmed
In response to glucocorticoid - induced
cytotoxicity , microvascular endothelial cells (
MVEC ) derived from
human brain were highly susceptible ,
MVEC derived from
human lung and
human liver sinusoidal endothelial cells were sub - sensitive , while AdrEC were highly resistant . -
pubmed
The importance of this case is that the
patient presented at the clinic with only
lumbar pain . -
pubmed
Only
Amitraz ( Preventic ) provided total control on transmission ( no dogs were infected ) , whereas with Frontline , Advantix , or Scalibor , the rate of
infection varied among the
dogs . -
pubmed
Neurotoxic lesions of the caudate - putamen on a reaching for food task in the
rat : acute
sensorimotor neglect and chronic qualitative motor impairment follow lateral lesions and improved success follows medial lesions . -
pubmed
Although changes in the end - point measure of success document the effects of
neurotoxic cellular damage to the caudate - putamen and its treatment in
rodents , there has been no examination of the cause of change in success after
neurotoxic lesions of the striatum . -
pubmed
The patient was a 61 - year - old
man with
chronic hepatitis C who achieved a sustained virological response to
interferon therapy in 1993 . -
pubmed
Even if
patients with
chronic hepatitis C have achieved a sustained virological response to
interferon therapy ,
patients with risk factors for the development of
hepatocellular carcinoma , such as being a male of advanced age and with progressive
fibrosis of the liver , should receive careful long - term follow - up . -
pubmed
[ Upper gastrointestinal
hemorrhage in a cardiac
patient with
chronic renal insufficiency ] . -
pubmed
Issues in the design and interpretation of
chronic toxicity and
carcinogenicity studies in
rodents : approaches to dose selection . -
pubmed
For more than three decades chronic studies in
rodents have been the benchmark for assessing the potential long - term toxicity , and particularly the
carcinogenicity , of chemicals . -
pubmed
Altered intestinal permeability in
patients with primary
fibromyalgia and in
patients with
complex regional pain syndrome . -
pubmed
OBJECTIVES : The
pain intensity of
patients with
FM has recently been reported to be correlated with the degree of small intestinal bacterial overgrowth (
SIBO ) . -
pubmed
We therefore examined the
IP in a group of
patients with primary
FM and in two control groups , healthy
volunteers and
patients with an unrelated
chronic pain syndrome ,
complex regional pain syndrome (
CRPS ) . -
pubmed
We hypothesized that
patients with
FM , but not
volunteers or those
patients with
CRPS , would have altered IP . -
pubmed
RESULTS : Forty
patients with primary
FM , 57 age- and sex - matched
volunteers and 17
patients with
CRPS were enrolled in this study . -
pubmed
Participants diagnosed with
ASDs had significantly ( P & lt ; 0.001 ) decreased plasma reduced
GSH , plasma
cysteine , plasma
taurine , plasma
sulfate , and plasma free
sulfate relative to controls . -
pubmed
The present observations are compatible with increased oxidative stress and a decreased detoxification capacity , particularly of
mercury , in
patients diagnosed with
ASDs . -
pubmed
Patients diagnosed with
ASDs should be routinely tested to evaluate transsulfuration metabolites , and potential treatment protocols should be evaluated to potentially correct the transsulfuration abnormalities observed . -
pubmed
UNLABELLED : The purpose of this study is to explore the clinical , biochemical and hormonal changes due to the use / prescription of
rosiglitazone to
women with
PCOS . -
pubmed
MATERIALS AND METHODS : The study includes 15
women with
PCOS and clinical data on
insulin resistance , that were treated with a daily dose of 4 mg
rosiglitazone (
Avandia ) for 3 months . -
pubmed
The use of wireless capsule enteroscopy in a preclinical study : a novel diagnostic tool for
indomethacin - induced
gastrointestinal injury in experimental
pigs . -
pubmed
METHODS : The experimental
animal species were small adult
pigs ( n=10 ;
body weight 30 - 35 kg ; 4 - 5 months old ) used for their relative physiological and metabolic resemblance to
man . -
pubmed
The following experimental methods were used for diagnostic verification of gastrointestinal
lesions ( damage scale : 1 - erosions , red
spots , inflammatory infiltration , 2 - single
ulcers , 3 - strings of
ulcers ): endoscopic image for the diagnostics of gastro - duodenal segment ( in vivo conditions ) , confocal laser microscopy ( ex vivo imaging ) and optical light microscopy ( in vitro ) , small intestinal imaging by means of wireless capsule enteroscopy ( in vivo ) , macroscopic findings and optical light microscopy ( after
animal sacrifice ) . -
pubmed
Interleukin-12 ( IL-12 )- deficiency promotes photocarcinogenesis in
mice ; however , the molecular mechanisms underlying this effect have not been fully elucidated . -
pubmed
We present the sixth known case of extragingival
PA in the buccal mucosa , which occurred in an 88 - year - old
woman . -
pubmed
Efficacy and durability of the
titanium mesh cage spacer combined with transarticular screw fixation for atlantoaxial instability in
rheumatoid arthritis patients . -
pubmed
SUMMARY OF BACKGROUND DATA : There have been few studies about atlantoaxial fusion rate and advantages for
titanium mesh cage from comparison with AIBG in
rheumatoid arthritis (
RA )
patients . -
pubmed
METHODS : Between January 1998 and October 2007 , 55
RA patients were surgically treated for
AAI . -
pubmed
We also could prevent donor site morbidities frequently seen in
patients with surgical treatment for
AAI . -
pubmed
BACKGROUND : Branch
retinal vein occlusion (
BRVO ) is a common
retinal vascular disorder of the
elderly and both intravitreal
triamcinolone acetonide ( TA ) and intravitreal
bevacizumab were reported to be effective . -
pubmed
BACKGROUND : It is necessary to develop a highly specific and sensitive assay to quantify the exact amount of
hepatitis C virus (
HCV ) RNA in blood of
patients with
hepatitis C. -
pubmed
The term
catamenial epilepsy is used to describe the cyclical occurrence of
seizure exacerbations during particular phases of menstrual cycle in
women with preexisting
epilepsy . -
pubmed
METHODS : We examined the safety of proximal gastrectomy by analyzing the lymph node
metastasis rate in 53
patients who underwent total gastrectomy due to proximally located early
gastric cancer from January 2004 to December 2008 . -
pubmed
Fifteen
patients underwent proximal gastrectomy using a new method which left no gastrostomy
wound for the insertion of a circular stapler in the remaining stomach . -
pubmed
METHODS AND STUDY DESIGN : Clinical and imaging features of 31 male
patients with
breast lesions were retrospectively evaluated and correlated with core needle biopsy results . -
pubmed
OBJECTIVES : We evaluated the efficacy and safety of the percutaneous ventricular assist device ( pVAD ) in
patients in severe refractory
cardiogenic shock (
SRCS ) despite intra - aortic balloon pump ( IABP ) and/or high - dose vasopressor support . -
pubmed
RESULTS : Eighty
patients had
ischemic and 37
patients had nonischemic
cardiomyopathy . -
pubmed
CONCLUSIONS : The pVAD rapidly reversed the terminal hemodynamic compromise seen in
patients with
SRCS refractory to IABP and vasopressor support . -
pubmed
RESULTS : We present the first report of an infected abdominal aortic graft , secondary to an ileal
perforation , in a 76 - year - old
woman presenting with bilateral iliopsoas
abscess . -
pubmed
The outbreak resulted in the
death of 97 animals ( 42
cattle , 52
dogs , and 3 horses ) . -
pubmed
[ Limb ischemic preconditioning decreases
hippocampal ischemia /
reperfusion injuries in
rats ] . -
pubmed
Global
cerebral ischemia was performed by four vessels occlusion in
rats . -
pubmed
Second , we evaluated resected megacolonic specimens of four
patients suffering from chronic
Chagas ' disease . -
pubmed
PURPOSE :
Patients with
hepatitis B e antigen (
HBeAg)-positive
chronic hepatitis B , who achieve
HBeAg seroconversion 6 months after completing 48 weeks of
peginterferon alfa-2a therapy , have an increased chance of clearing
hepatitis B surface antigen (
HBsAg ) during long - term treatment - free follow - up . -
pubmed
Radioactivity of blood samples taken from
thyroidectomized thyroid carcinoma patients after therapy with
( 131 ) I. -
pubmed
BACKGROUND : Occasionally , blood samples may be required from
thyroid cancer patients after they have been given the therapy dose of
( 131 ) I , as part of necessary medical management of comorbidities . -
pubmed
The purpose of this study was to quantify the amount of radioactivity in blood samples taken from thyroidectomized
thyroid carcinoma patients after the administration of therapeutic activities of
( 131 ) I. -
pubmed
METHODS : For dosimetry purposes , serial blood sampling is performed on thyroidectomized thyroid
carcinoma patients prior to therapy with
( 131 ) I. -
pubmed
Here we describe how the use of near - infrared dyes and fluorescence laparoscopy could help improve
tumour staging and therefore lead to better selection of
patients for postoperative adjuvant chemotherapy . -
pubmed
Evaluation of
wound - healing formulation against
sulphur mustard - induced
skin injury in
mice . -
pubmed
Sulphur mustard ( SM ) is a bifunctional alkylating agent that causes cutaneous
blisters in
human and animals . -
pubmed
Due to inevitable requirement of a
wound - healing formulation against SM - induced
skin lesions , efficacy of formulations including
povidone iodine ,
Aloe vera gel ,
betaine or
framycetin sulphate was evaluated in present study . -
pubmed
Blood samples were collected from a cohort of
children under intensive surveillance for
Plasmodium falciparum parasitaemia and illness . -
pubmed
The pathology database was queried for all
patients with
DCIS from January 2004 to September 2008 . -
pubmed
METHODS : A retrospective , consecutive , noncomparative cases series of DALK procedures in a total of 806 eyes of 711
patients with
stromal diseases and healthy endothelium performed between 2000 and 2009 . -
pubmed
RESULTS : 9 ( 3.3 % ) of 270
patients underwent surgery to remove esophageal
foreign bodies . -
pubmed
[
Abnormal glucose tolerance in prepubertal
patients with
cystic fibrosis ] . -
pubmed
PATIENTS AND METHODS : Retrospective study of 19 prepubertal
CF patients ( 68 %
males ) . -
pubmed
In follow - up : 4/10 NGT
patients developed
AGT ( 3
IGT , 1
CFRD ) . -
pubmed
The lateral
RA was selected in
children & gt;1 yr of age without abnormal migration or fusion of the kidney ( n=104 ) . -
pubmed
BACKGROUND : Recent studies have identified
HIV as a leading contributor to
preterm delivery and its associated morbidity and mortality . -
pubmed
This study was designed to determine the incidence and risk factors for
preterm delivery in
HIV positive Nigerians . -
pubmed
HIV positive women with multiple pregnancies , symptomatic
HIV infection at delivery and first trimester fetal exposure to
PI based triple therapy were found to be at risk of spontaneous
preterm delivery . -
pubmed
BACKGROUND : To obtain a prognostic stratification model for resected
gastric cancer patients . -
pubmed
METHODS : The
patient presented with a sternal mass 4 years after undergoing coronary artery bypass grafting for
ischemic coronary artery disease . -
pubmed
[
Bleeding in the appointment of
dabigatran in the
patients with
renal insufficiency caused by coadministration of
spironolactone and
ACE inhibitors ] . -
pubmed
It is a case report of
bleeding when using
dabigatran in
patient with
renal failure caused by the concurrent use of
spironolactone and
angiotensin - converting enzyme ( ACE ) inhibitors . -
pubmed
The
patient ( 75 years old ) at the decompensation of chronic
heart failure in the background of persistent
atrial fibrillation was appointed the combination of
ACE inhibitors ,
spironolactone , and
dabigatran . -
pubmed
The complete clinical trials thus far have showen that those tested chemosensitizers only add limited or no benefits to
cancer patients . -
pubmed
Available evidence does not support the routine use of higher positive end expiratory pressure ( PEEP ) in
patients with
ARDS . -
pubmed
CONCLUSIONS : A lumbar support pillow with a cut - out for the posterior pelvic tissues improved an objective measure of comfort in healthy individuals and
patients with
low back pain . -
pubmed
Factors associated with initiation of chronic renal replacement therapy for
patients with
kidney failure . -
pubmed
BACKGROUND AND OBJECTIVES :
Patients with
kidney failure sometimes do not receive chronic renal replacement therapy ( RRT ) , even though this may reduce their life expectancy . -
pubmed
Neurocognitive functioning in
patients with first - episode
schizophrenia 1 year from onset in comparison with
patients 5 years from onset . -
pubmed
Therefore , we followed
patients with first - episode
schizophrenia to verify the course of these deficits . -
pubmed
METHODS : In Study 1 , tests of neurocognitive functioning were administered to
patients with first - episode
schizophrenia (
FE group ) every 6 months . -
pubmed
Here we report an in - depth evolutionary analysis of whole - genome sequence data of 45
H7N9 and 42
H9N2 viruses isolated from
humans , poultry , and wild birds during recent
influenza surveillance efforts in China . -
pubmed
Our study identifies the pathways for the generation of diverse
H7N9 genotypes in China and highlights the importance of monitoring multiple sources for effective surveillance of potential
influenza outbreaks . -
pubmed
A 2007 observational cohort study in Bihar of 251
patients with
VL treated with 20 mg / Kg intravenous liposomal
amphotericin B (
Ambisome ) demonstrated a 98 % cure rate at 6 - months . -
pubmed
SIGNIFICANCE : This is the largest cohort of
VL patients treated with 20 mg / kg
Ambisome worldwide . -
pubmed
OBJECTIVES : The purpose of this study was to assess the prevalence and characteristics of
dental erosion in
children aged 2 - 4 years old and 12 years old . -
pubmed
Bartholin ' s Gland Abscesses Caused by
Streptococcus pneumoniae in a Primigravida . -
pubmed
In this report , we describe a case of
Bartholin ' s abscess caused by
Streptococcus pneumoniae in a 25 - year - old non -
diabetic primigravida . -
pubmed
METHODS AND RESULTS : We present a rare case of a 63 - year - old
man with
dermatomyositis as a
paraneoplastic syndrome developing more than a year before clinical manifestations of
tonsillar squamous cell carcinoma (
SCC ) . -
pubmed
Circulating
tumor cells ( CTCs ) can be detected in the blood of
patients with nearly all types of locally and metastatic
adenocarcinomas . -
pubmed
BACKGROUND : Multiple independent culture - based studies have identified the presence of
Pseudomonas aeruginosa in respiratory samples as a positive risk factor for
bronchiolitis obliterans syndrome (
BOS ) . -
pubmed
Night time symptoms (
snoring , frequent night awakenings ,
restless sleep ) were present in 294
children , and 161 children had daytime symptoms ( excessive
daytime sleepiness , early morning
fatigue , poor concentration at school ) . -
pubmed
Heart rate variability is reduced in
acromegaly patients and improved by treatment with
somatostatin analogues . -
pubmed
However , few data are available on cardiac autonomic functions and sympathovagal balance in
acromegalic patients . -
pubmed
OBJECTIVE : The aim of this study was to investigate both the time and frequency domain parameters of Heart Rate Variability ( HRV ) , in order to characterize the cardiac autonomic functions in
patients affected by
acromegaly . -
pubmed
MATERIALS AND METHODS : This study enrolled 47
acromegalic patients ( 23
males , age 49.1 + - 13.5 years ) and 37 ( 13
males ) age matched ( 52.3 + - 13.3 years ) healthy
subjects . -
pubmed
The HRV of 28
acromegalic patients was studied before and after SSAs treatment . -
pubmed
RESULTS :
Acromegalic patients showed significantly lower SDNN and SDANN compared to controls . -
pubmed
Diabetic and non - diabetic acromegalic patients showed decreased SDNN and SDANN , when compared to healthy subjects . -
pubmed
Similar results were obtained analyzing
patients affected by
acromegaly and
impaired glucose tolerance . -
pubmed
Patients with
ventricular arrhythmias in Lown classes 3 - 5 showed a decreased SDANN compared to
patients in Lown class 0 - 2 . -
pubmed
CONCLUSION : Cardiac autonomic functions and sympathovagal balance are altered in
patients affected by
acromegaly and could be ameliorated by SSAs therapy . -
pubmed
HRV analysis allows an estimation of the autonomic sympathovagal balance and may be a useful clinical tool for the cardiac risk stratification in
acromegalic patients . -
pubmed
The aim was to assess the effect of omega-3 supplementation on Body Mass Index (
BMI ) , Wais - Hip Index ( WHI ) and body composition of
obese women using bioelectrical impedance . -
pubmed
Subjects 60 premenopausal
obese women (
BMI & gt ; 30Kg / m2 ) were randomly assigned to 3 groups : Group 1 ) placebo ,
vitamin E ( 200 IU ) , group 2 ) 1 g of omega and group 3 ) 2 g of omega-3 . -
pubmed
METHODS : This retrospective observational case series included 18 eyes ( 18
patients ) with typical exudative age - related
macular degeneration with a baseline best - corrected visual acuity of 20 / 25 or better . -
pubmed
CONCLUSIONS :
Deterioration in visual acuity was noted in eyes with typical exudative age - related
macular degeneration with good baseline visual acuity , suggesting the need for close
patient monitoring and prompt treatment even in
patients with good baseline visual acuity . -
pubmed
OBJECTIVES : In this study , we aim to predict the recovery of upper limb function in
patients in the acute phase of
cerebrovascular disease . -
pubmed
RESULTS : A total of 357
patients with
cerebrovascular disease were analyzed on the basis of diagnosis [
cerebral infarction ( CI ; 77.6 % ) ,
cerebral hemorrhage (
CH ; 20.2 % ) ,
subarachnoid hemorrhage (
SAH ; 2.2 % ) ] . -
pubmed
CONCLUSIONS : In this report , we described the study design and characteristics of
patients with
cerebrovascular disease at baseline . -
pubmed
Prediction of need for surgery after endoscopic balloon dilation of ileocolic
anastomotic stricture in
patients with
Crohn ' s disease . -
pubmed
PATIENTS : All of the eligible
patients with ileocolic anastomotic
stricture attributed to recurrent
Crohn ' s disease treated with endoscopic dilation between December 1998 and May 2013 were evaluated . -
pubmed
Patients with concurrent enterocutaneous
fistula or
abdominal or pelvic abscess were excluded . -
pubmed
RESULTS : A total of 185
patients with
Crohn ' s disease ( 45.9 %
women ; mean age , 43.1 years ; symptomatic
strictures in 80 % ) underwent 462 endoscopic dilations of ileocolic anastomosis ( median per - patient dilations , 2 ; range , 1 - 3 ) . -
pubmed
During a mean follow - up of 3.9 years , 27
patients ( 14.6 % ) required hospitalization without surgery for
stricture - related symptoms , and 66 patients ( 35.7 % ) required subsequent salvage surgery . -
pubmed
A 72 - year - old
man presented to the high dependency unit following an elective incisional
hernia repair . -
pubmed
The in vitro study was conducted on
human meningioma primary cells extracted from
fresh tumors , allowing the assessment of
somatostatin analogs at the concentration levels used in
patients . -
pubmed
We have demonstrated a co - operative action between
everolimus and
octreotide on cell proliferation in
human meningiomas , including aggressive ones , establishing the basis for a clinical trial . -
pubmed
Risk factors associated with
end - stage renal disease (
ESRD ) in
patients with
atherosclerotic renal artery stenosis : a nationwide population - based analysis . -
pubmed
Of note , our data showed that renal artery revascularization was associated with a lower risk of
ESRD in
ARAS patients in long - term follow - up . -
pubmed
The interaction effects of aerobic exercise training and
vitamin D supplementation on plasma lipid profiles and
insulin resistance in ovariectomized
rats . -
pubmed
PURPOSE : The purpose of this study was to determine the interaction effects of aerobic exercise training and
vitamin D supplementation on indices of
obesity and plasma lipid profiles in ovariectomized ( OVX )
rats . -
pubmed
Strain differences in antioxidants in
rat models of
cardiovascular disease exposed to
ozone . -
pubmed
We examined the hypothesis that antioxidant substances and enzymes in lung , heart and in bronchoalveolar lavage fluid ( BALF ) are altered in response to
O3 in
cardiovascular disease and/or
metabolic syndrome (
CVD)-prone
rat models . -
pubmed
CVD rats tended to respond less to
O3 than normal . -
pubmed
In summary , large differences were observed between both normal and
CVD rat strains in low - molecular weight antioxidant concentrations in lung , BALF and heart tissue . -
pubmed
Wistar ( normal ) and JCR and SHHF (
CVD )
rats appeared to stand out as peculiar in terms of basal- or
O3 - induced changes . -
pubmed
RESULTS : Significant
valvular heart disease increases perioperative risk in major non - cardiac surgery and increases long term
patient morbidity and mortality . -
pubmed
METHODS :
Patients with a history of primary
lateral patellar dislocation between 2008 and 2012 were prospectively identified . -
pubmed
Characterizing knee anatomic imaging factors in the
patient with a primary
lateral patellar dislocation is a necessary first step in characterizing the ( potential ) differences between the primary and recurrent
patellar dislocation patient . -
pubmed
Biomechanical comparison of 3.0 mm headless compression screw and 3.5 mm cortical bone screw in a
canine humeral
condylar fracture model . -
pubmed
METHODS : Bilateral humeri were collected from nine
canine cadavers . -
pubmed
CASE REPORTS : Case 1 was a 12 - year - old male
patient with anisometropic "
amblyopia " in the right eye , MRNF denser superiorly , a
hypoplastic disc , and a
myopic fundus with a flat intact macula . -
pubmed
Case 2 was a 10 - year - old male
patient with a
constant left esotropia , MRNF denser superiorly , a
hypoplastic disc , and a
myopic fundus with a flat intact macula . -
pubmed
Case 3 was a 58 - year - old female
patient with a history of
diabetic retinopathy OU , long - standing
reduced vision in the right eye , MRNF denser superiorly ,
optic nerve hypoplasia , and a
myopic fundus with an intact macula . -
pubmed
CONCLUSIONS : This case series identifies three
patients with the
syndrome of
MRNF ,
optic nerve hypoplasia , and
anisomyopia in one eye with
reduced vision and reports OCT findings using SD - OCT systems . -
pubmed
Patients with this
syndrome may have a guarded prognosis in the success of vision therapy . -
pubmed
In view of the inter -
individual differences in anatomy , physiological reserves , and severity of
pathological processes , neuromonitoring may be a valuable method to evaluate the well - being of the nervous system during and after surgical interventions . -
pubmed
Vitrectomy for complications of proliferative
diabetic retinopathy in young
adults : clinical features and surgical outcomes . -
pubmed
PURPOSE : To investigate the clinical manifestations and surgical results after vitrectomy for
proliferative diabetic retinopathy (
PDR ) in young
patients . -
pubmed
Patients with Type 1 and
Type 2 diabetes mellitus subgroups shared similar clinical features and visual outcome . -
pubmed
Methods : Ten
patients ( 8
women and 2
men ) with
skin - picking disorder ( per DSM-5 criteria ) were enrolled in the study . -
pubmed
As a demonstration for mobile applications , these BJT sensors are further investigated by measuring
chloride levels in artificial
human sweat for potential
cystic fibrosis diagnostic use . -
pubmed
We report the clinical presentation , diagnostic approach , and therapy of four
children with progressive
pPACNS . -
pubmed
In the present review , the beneficial effects of the most investigated nutraceutical compounds in the setting of
human IBD are discussed . -
pubmed
Unlike many of the nontyphoidal Salmonella serovars such as S. Typhimurium that cause restricted
gastroenteritis ,
Salmonella Typhi is unique in that it causes life - threatening
typhoid fever in
humans . -
pubmed
This article discusses the current understanding of
typhoid toxin and potential directions for future research endeavors in order to better understand the contribution of
typhoid toxin to
S . - pubmed
This enabled the identification of a viral agent in 71.3 % ( 231/324 ) of unidentified surveillance samples , including common respiratory pathogens ( 100/324 ; 30.9 % ): enterovirus ( 16/100 ; 16.0 % ) ,
coxsackievirus ( 31/100 ; 31.0 % ) ,
echovirus ( 22/100 ; 22.0 % ) ,
human rhinovirus ( 3/100 ; 3 % ) , enterovirus genus ( 2/100 ; 2.0 % ) ,
influenza A ( 9/100 ; 9.0 % ) ,
influenza B , ( 5/100 ; 5.0 % ) ,
human parainfluenza ( 4/100 ; 4.0 % ) ,
human adenovirus ( 3/100 ; 3.0 % ) ,
human coronavirus ( 1/100 ; 1.0 % ) ,
human metapneumovirus ( 2/100 ; 2.0 % ) , and
mumps virus ( 2/100 ; 2.0 % ) , in addition to the non - respiratory pathogen
herpes simplex virus type 1 (
HSV-1 ) ( 172/324 ; 53.1 % ) and
HSV-1 co - infection with respiratory viruses ( 41/324 ; 12.7 % ) . -
pubmed
EDTA - induced
pseudothrombocytosis and
citrate - induced
platelet agglutination in a
patient with
Waldenstrom macroglobulinemia . -
pubmed
A
patient had
EDTA - induced
pseudothrombocytosis and
platelet agglutination in
citrate blood samples . -
pubmed
This is the case of a 43 years - old
woman who presented with severe
headaches 9 years ago ( 2008 ) . -
pubmed
We report the case of a 56 - year - old
man who presented a persistent
urticarial rash and
anaphylactic shock after a mitral valve repair operation . -
pubmed
Materials and Methods : One hundred and twenty - seven
patients with
diabetes mellitus attending our outpatient were randomized into intervention ( n = 63 ) and control groups ( n = 64 ) . -
pubmed
Patient education module consisted of an audio - visual display and a pamphlet on
diabetes foot care . -
pubmed
Methods : Retrospective chart review of 162 biopsy - proven
MMP patients . -
pubmed
Results : At presentation , 109 of 162
MMP patients ( 67.3 % ) had ocular involvement and 53
patients did not . -
pubmed
Conclusions :
Patients presenting with
extraocular MMP are at risk for developing
ocular MMP , and all MMP
patients are at risk for developing secondary extraocular MMP locations , although the rates were low . -
pubmed
Bovine spongiform encephalopathy (
BSE ) can be efficiently transmitted to
pigs via intracerebral inoculation . -
pubmed
A clear link has been established between the consumption of products of
bovine origin contaminated with the BSE agent and the development of variant
Creutzfeldt - Jakob disease in
humans . -
pubmed
Clinical characteristics of
cognitive impairment in
patients with
Parkinson ' s disease and its related pattern in
18 F - FDG PET imaging . -
pubmed
We recruited 168
PD patients and 100 age - matched healthy controls of similar education and gender distribution . -
pubmed
In 53
PD patients who underwent
18 F - fluorodeoxyglucose (
18 F - FDG ) PET imaging , correlations between Z - score values of the different cognitive domains and cerebral
18 F - FDG uptake were assessed using statistical parametric mapping ( SPM8 ) corrected for age and motor severity . -
pubmed
A total of 23.2 % of
PD patients were
PD - MCI and 8.9 % were
PD - D. -
pubmed
In this report , we review poststroke psychiatric manifestations , and then present the case of a
woman with
schizophrenia whose
thought disorder improved following a
hemorrhagic stroke . -
pubmed
Diagnostic paracentesis is indicated in all
patients with a new onset of grade 2 or 3
ascites and in those admitted to hospital for any complication of
cirrhosis . -
pubmed
A careful selection of
patients is also important to obtain the beneficial effects of transjugular intrahepatic portosystemic shunts in refractory
ascites . -
pubmed
Improve
hip fracture outcome in the elderly
patient ( iHOPE ): a study protocol for a pragmatic , multicentre randomised controlled trial to test the efficacy of spinal versus general anaesthesia . -
pubmed
INTRODUCTION :
Hip fracture surgery is associated with high in - hospital and 30 - day mortality rates and serious adverse
patient outcomes . -
pubmed
Evidence from randomised controlled trials regarding effectiveness of spinal versus general anaesthesia on
patient - centred outcomes after
hip fracture surgery is sparse . -
pubmed
In total , 1032
patients with
hip fracture ( & gt;65 years ) will be randomised in an intended 1:1 allocation ratio to receive spinal anaesthesia ( n=516 ) or general anaesthesia ( n=516 ) . -
pubmed
In pigs ,
Senecavirus A ( SVA ) causes a
vesicular disease that is clinically indistinguishable from
foot - and - mouth disease ,
vesicular stomatitis and
swine vesicular disease . -
pubmed
Anemic patients affected by
BT suffer from
iron overload , even in the absence of chronic blood transfusion , suggesting the presence of & gt;=1 erythroid factor with the ability to modulate
iron metabolism and dietary
iron absorption . -
pubmed
In fact , genetic or pharmacological manipulations of
iron metabolism or erythroid cell differentiation and survival have been shown to improve
IE ,
iron overload , and
anemia in
animal models of
BT . -
pubmed
However , its clinical significance in
COPD patients is poorly understood . -
pubmed
Replacement of the
Thiosugar of
Auranofin with
Iodide Enhances the Anticancer Potency in a
Mouse Model of
Ovarian Cancer . -
pubmed
The present study shows that the
iodido ( triethylphosphine ) gold ( I ) complex , ( Et 3 PAuI hereafter)-an AF analogue where the
thiosugar ligand is simply replaced by one
iodide ligand - manifests a solution chemistry resembling that of AF and exerts similar cytotoxic and proapoptotic effects on
A2780 human ovarian cancer cells in vitro . -
pubmed
Multi - stage surgery for a multiple - level
spondylodiscitis caused by multidrug - resistant
Mycobacterium avium complex . -
pubmed
At 1 year after surgery , the
patient suffered a proximal junctional failure secondary to a
vertebral fracture that was solved with a proximal extension of the fusion using a percutaneous technique . -
pubmed
The
patient was successfully discharged with good
pain control , satisfactory correction , no neurologic complications and an overall satisfactory outcome . -
pubmed
ETHNOPHARMACOLOGICAL RELEVANCE :
Atopic dermatitis (
AD ) , a disorder prevalent during childhood and adulthood , seriously affects the
patient 's quality of life . -
pubmed
One novelty in the present study is the use of
human CL cases to predict the risk of
leishmaniasis occurrence in response to anthropogenic , climatic and environmental factors at two different scales , in the Neotropical moist forest biome ( Amazonian basin and surrounding forest ecosystems ) and in the surrounding region of French Guiana . -
pubmed
The predominantly identified
human CL risk areas are those where the
human impact on the environment is significant , associated with less contributory climatic and ecological factors . -
pubmed
For both models this study highlights the importance of considering the anthropogenic drivers for disease risk assessment in
human , although
CL is mainly linked to the sylvatic and peri - urban cycle in Meso and South America . -
pubmed
METHODS : We conducted a retrospective study of
patients who underwent curative resection for
non - small cell lung cancer between 1998 and 2011 . -
pubmed
In multivariate analysis of the whole cohort , older
patients , male gender ,
non - adenocarcinoma histology , more advanced pathological stage of
lung cancer ,
interstitial pneumonia , and previous
extrathoracic malignancies were associated with significantly worse prognosis . -
pubmed
When propensity - score matched cohorts were compared , prognosis was significantly worse in
patients with previous
extrathoracic malignancies than those without ( 5 - year survival rates ; 75.3 % versus 82.7 % , p = 0.009 ) , although
recurrence was not frequently seen ( 5 - year
recurrence free rates ; 78.7 % versus 83.0 % , p = 0.491 ) . -
pubmed
Proteomic Analysis of
Dpy19l2 - Deficient Human Globozoospermia Reveals Multiple Molecular Defects . -
pubmed
This multicenter study aims to develop and validate a novel and easy - to - access model for predicting the prognosis of
patients with
cirrhosis and
acute GIB . -
pubmed
METHODS :
Patients with
cirrhosis and acute
GIB were enrolled and randomly divided into the training ( n = 865 ) and validation ( n = 817 ) cohorts . -
pubmed
CONCLUSION : CAGIB score has a good predictive performance for prognosis of
patients with
cirrhosis and
acute GIB . -
pubmed
An 83 - year - old
man suffered from
cerebral infarction of the right middle cerebral artery territory . -
pubmed
We intend to awaken an interest in the medication history of
patients presenting with
sudden diffuse alopecia areata . -
pubmed
Epigallocatechin gallate (
EGCG ) , a major component of
green tea , has been shown to possess a wide range of pharmacological properties , including anti -
inflammation and
anti - viral infection . -
pubmed
Methods : A total of 301
patients with newly diagnosed
thyrotoxicosis and without any anti - thyroid drug intervention were collected from the Department of Endocrinology and Metabolism , Peking University People 's Hospital from Jan. 2015 to Oct. 2018 . -
pubmed
Among them , 241
patients were with
Graves ' disease (
GD ) and 60
patients were with
autoimmune thyroiditis (
AIT ) . -
pubmed
The significant antibacterial activities of the TGQDs were found against a highly pathogenic bacterium (
Staphylococcus aureus ) and its antibiotic resistant
strains (
vancomycin and
methicillin resistant
Staphylococcus aureus ) using growth curve analysis and determination of minimum inhibitory concentration ( MIC ) analysis . -
pubmed
METHODS : A cross - sectional historical study was conducted including 219
patients aged 3 - 18 years who presented to a tertiary pediatric
headache clinic in 2016 - 2017 . -
pubmed
The prevalence of a positive history of
colic was compared between
children diagnosed with
migraine or other primary
headache types . -
pubmed
Migraine headache was diagnosed in 170
patients ( 77.6 % ) and other types primary of
headache ( 9 in total ) in 49
patients ( 22.3 % ) . -
pubmed
Fifty - one
patients had a history of
infantile colic . -
pubmed
They included 45
patients in the
migraine group ( 26.5 % ) and 5 in the comparison groups ( 10.2 % ) ; the difference in the rate of
colic was statistically significant ( P = .0196 ; OR 3.17 , 95 % CI 0.1.17 - 6.17 ) . -
pubmed
Methods : We report a case of
crystalluria in a
patient treated empirically with intravenous
acyclovir for possible
viral meningitis . -
pubmed
Toxicity of the synthesized NPs was tested on
green gram (
Vigna radiata ) seed at various concentrations ( 20 - 100 % ) and germination was induced by NPs treated seeds . -
pubmed
In addition , a xenograft
tumor model was established in
mice to evaluate the impact of miR-130a-3p on
tumor growth in vivo . -
pubmed
Overexpression of miR-130a-3p also promoted
tumor growth in
mice . -
pubmed
METHODS : Ten
RA subjects received 30
HBO2 treatments over 6 to 10 weeks . -
pubmed
Serial rheumatologic evaluations ( ie , the Disease Activity Scale [ DAS28 ] , the Routine Assessment of
Patient Index Data 3 , and the
Pain and Sleep Quality Questionnaire ) were completed at baseline , throughout the course of the study , and at the 6 - month follow - up . -
pubmed
CONCLUSIONS : Hyperbaric
oxygen therapy is effective for
joint pain in
patients with
RA based on data from multiple , validated clinical measures . -
pubmed
Functions of
tumor - associated macrophages and macrophages residing in remote anatomical niches in
Ehrlich carcinoma bearing
mice . -
pubmed
MATERIALS AND METHODS : Ehrlich
carcinoma was transplanted intramuscularly to
Balb / c male mice . -
pubmed
However , we have limited methods to evaluate ROS in
tumor tissues and little knowledge on ROS metabolism across
human cancers . -
pubmed
Conclusion : Our study proposes a new method in evaluating ROS status and offers comprehensive understanding on ROS metabolic equilibrium in
human cancers , which provide practical implications for clinical management . -
pubmed
Innovations in early
stroke detection and individualized
patient selection for reperfusion therapies have equipped the emergency medicine clinician with more opportunities to help
stroke patients and minimize the impact of this disease . -
pubmed
Methods : From March 2016 to January 2020 , 25
patients with
diabetic foot wounds were admitted to the First Affiliated Hospital of Air Force Medical University , including 18 males and 7 females , with age of 40 to 70 years . -
pubmed
Two weeks after the suturing operation , the healing grade of the foot
wound of
patients was observed , and the serious complications such as
recurrence of
ulcer wound and
gangrene on the foot ,
scar condition of the
wound were observed during follow - up . -
pubmed
Results : Two weeks after the suturing operation , the
wounds of 23
patients were healed with grade A. -
pubmed
Soft tissue
infection ulcer relapsed in 2
patients during the stretch period . -
pubmed
During the follow - up of 3 to 36 months , 23
patients had linear
scar left on the stretch
wounds , and the skin elasticity , color , sensation was similar to the surrounding normal tissue , and the limb mobility was good , and 2 patients had obvious
scar hyperplasia . -
pubmed
One
patient had
recurrence of
diabetic foot and serious
vascular occlusion and
gangrene in the affected limb at follow - up of 10 months , which was treated with amputation of the lower leg . -
pubmed
RESULTS : Overall , 3606 ( 66 % ) and 987 ( 18 % )
patients had
LS < 10 and > 15 kPa , respectively , while cACLD was histologically confirmed in 1772 ( 31 % ) patients . -
pubmed
Among 2260
patients with
critical illness or
injury receiving HEMS , compared with 315
patients with
critical illness or
injury receiving GEMS , adjusted cumulative 1 - year mortality was 25.1 % ( 95 % CI , 23.5%-26.7 % ) vs 27.1 % ( 95 % CI , 22.0%-32.1 % ) . -
pubmed
Case 1 : A 51 - year - old
man with advanced
gastric cancer and
peritoneal metastasis was referred to our hospital . -
pubmed
Case 2 : A 75 - year - old
woman with recurrence of peritoneally disseminated
gastric cancer received third - line chemotherapy with
nivolumab . -
pubmed
Background : There are limited psychometrically sound measures to assess higher level balance in
individuals with incomplete
spinal cord injury (
iSCI ) . -
pubmed
Methods : Twelve
participants ( 11
male , 1 female ) 32 to 73 years old with chronic motor
iSCI , American Spinal Injury Association Impairment Scale C ( n = 2 ) or D ( n = 10 ) , were included . -
pubmed
A 22 - year - old
man with a ventriculoatrial shunt was admitted to hospital for investigation of
headache ,
nausea and
vomiting . -
pubmed
[ Incidence of antibodies to RS virus in
children with acute
respiratory diseases ] . -
pubmed
The influence of
D - Penicillamine on protein synthesis in synovial fluid cells was investigated in 5
patients suffering from
rheumatoid arthritis . -
pubmed
Low serum
triiodothyronine in
patients with
anorexia nervosa . -
pubmed
Patients with
anorexia nervosa can demonstrate clinical and/or laboratory findings suggestive of reduced thyroid hormone secretion . -
pubmed
The extremely low serum levels of T3 in these
patients with
anorexia nervosa suggest that peripheral conversion of T4 to T3 is impaired during chronic
starvation . -
pubmed
The skin - window inflammatory cell response was studied in 64 adult
patients with various
malignant neoplasms before initiation of chemotherapy and was repeated when a neutrophil level of 2500 cells / mm3 or less occurred . -
pubmed
Of the 21
neutropenic patients , 15 had an abnormal neutrophil cell response and nine had an abnormal mononuclear cell response . -
pubmed
Of the nine
patients who had
infection , eight had an abnormal mononuclear cell response and seven of the eight had a concomitant abnormal neutrophil response . -
pubmed
The Rebuck skin window may be a practical clinical test to evaluate the risk for
infection in
neutropenic patients receiving
cancer chemotherapy . -
pubmed
We have carried out spectrofluorometric determinations of numerous substances such as drugs , chemicals and
plants in order to find out whether there is a correlation between fluorescence data and
photosensitization of the skin . -
pubmed
Although caution is required in extrapolation of in vitro data to the in vivo state , these findings suggest
rat seminiferous tubules may be incapable of de novo
testosterone biosynthesis and that this lack of synthetic ability may be due to a
deficiency of CSCCE . -
pubmed
A
patient is 18 years old ; he presents
Peters ' anomaly ,
microcornea , the persisting of papillar membrana ,
congenital specifying lens for both eyes and atypical
iridic coloboma for the right eye . -
pubmed
Synergistic effect of
romurtide with
ampicillin against
pneumococcal pneumonia in
mice . -
pubmed
In contrast , the combination treatment of
romurtide with
ABPC successfully prevented most of the
mice from the purulent
pneumonia : the initial infiltration of resident alveolar macrophages and subsequent accumulation of macrophages were observed in the pneumonic foci . -
pubmed
In accordance with the occurrence of these cellular responses in the lungs ,
pneumococci were successfully eliminated from the lungs in
mice treated with
romurtide in combination with
ABPC . -
pubmed
Thus ,
romurtide was suggested to promote recovery of the
mice with
pneumococcal pneumonia by activating resident and accumulated macrophages in the pneumonic foci to eliminate pneumococci from the lung . -
pubmed
Up to now , the best treatment for
patients with
acute myelogenous leukemia (
AML ) is the induction of
bone marrow hypoplasia by ablative combined chemotherapy ; the prototype of these schedules is the so - called 7 + 3 ( seven days of continuous infusion of
cytarabine and three days of one - hour infusion of any
anthracycline ) ; these schedules require the support of both platelet transfusions and antibiotics . -
pubmed
Here we analyze the results of the treatment of 76 adult
patients with
AML ; 43 were treated with the classical 7 + 3 schedule , whereas 33 were treated with a combination of chemotherapy used in non - ablative doses ( TADOP :
thioguanine ,
arabinosyl - citosine ,
doxorrubicin ,
vincristine and
prednisone ) . -
pubmed
When
Brucella melitensis strain Rev 1 vaccine ( Rev 1 ) is administered by the standard method ( 1 - 2 x 10(9 ) viable bacteria injected subcutaneously ) , it may induce long - lasting serological responses and/or cause
abortion in pregnant animals . -
pubmed
Treatment with ligno -
paraffin increased the skin surface temperature 8.9 degrees C ; the temperature in the joint cavity was increased 3.5 degrees C. CONCLUSION : The use of short - wave diathermy and superficial heat packs in the treatment of
patients with
arthritis may potentially cause harm by increasing intraarticular temperature . -
pubmed
This may have major implications regarding treatment policy for
patients with
arthritis . -
pubmed
The
murine skin multistage
carcinogenesis model was used to characterize the co - promoting and
tumor progressing activities of i.p . -
pubmed
C57BL / 6 mice initiated with
DMBA developed few
papillomas ( 0.2 paps /
mouse ) after 19 weeks of
TPA promotion . -
pubmed
Investigation of these possibilities in culture may provide insight into neuropathologic mechanisms operative in the
fetal alcohol syndrome or
alcohol - associated
peripheral neuropathy in
humans . -
pubmed
Transient chimaerism occurred in half of the cases and was accompanied by the temporary appearance of the Philadelphia chromosome in one
patient with
chronic myeloid leukaemia without subsequent
relapse . -
pubmed
Dose - dependent modifications of cellular
glutathione by
NaOCN and organic
isocyanates were observed in
human HT29 colon tumor cells ,
rat HTC
hepatoma cells , and
rat hepatocytes . -
pubmed
Does adjuvant radiotherapy have a role in the postmastectomy management of
patients with operable
breast cancer -- revisited . -
pubmed
Routine " adjunctive postmastectomy radiotherapy for all
patients with operable
breast cancer obviously is not indicated , but there appear to be groups of patients who benefit from radiotherapy , both from the standpoint of
disease - free survival and improved quality of life , and . -
pubmed
In response to the posed question , while this remains a controversial issue , there appears to be a role for selective adjunctive postmastectomy radiotherapy in specific subsets of
patients , and physicians administering adjunctive
breast cancer therapy with sweeping applications of chemotherapy or anti - hormones alone do not appear to be offering their
patients optimal therapy . -
pubmed
51
patients were not examined for
tuberculosis ( tuberculin test , chest x - ray , sputum investigation for tubercle bacilli , phthisiologist 's consultation , etc . ) -
pubmed
Comparison of the metabolic effects of long - term treatment with
pindolol or
atenolol by
hypertensive patients . -
pubmed
[ Induction of chemiluminescence of
human granulocytes by monocyte factors from
patients with
chronic polyarthritis and
arthrosis ] . -
pubmed
The supernatant of peripheral blood monocytes , cultured with autologous sera from
patients with
rheumatoid arthritis , stimulates healthy
human granulocytes to significantly elevated chemiluminescence ( p = 0.05 ) compared with supernatants of monocytes from
osteoarthritic patients or healthy
volunteers . -
pubmed
Louvain
rat immunocytomas . -
pubmed
Cell - mediated immunity in
uremic patients prior to and after 6 months ' treatment with continuous ambulatory peritoneal dialysis . -
pubmed
The number of circulating T - lymphocytes and their functional activity were studied in a group of 14
uremic patients prior to and after 6 to 9 months of treatment with continuous ambulatory peritoneal dialysis ( CAPD ) . -
pubmed
After CAPD a clear improvement in functional activity of the T cells was found in 4 of 10
patients with impaired
GVHR . -
pubmed
Migrating action potential complexes in a
patient with
secretory diarrhea . -
pubmed
A 70 - year - old
woman with
secretory diarrhea was studied with a novel technique of recording small intestinal myoelectrical activity which allowed us to obtain long , uninterrupted records of slow waves and spikes at eight or more different intestinal levels simultaneously . -
pubmed
This is the first report on MAPC activity in
man and on the association of this myoelectrical pattern with
secretory diarrhea in
man . -
pubmed
[ Polysaccharide containing fractions of
leptospira and possibilities of their applications for generic and specific diagnosis of
leptospiroses ] . -
pubmed
[ Acute
febrile mucocutaneous lymph node syndrome in
children ] . -
pubmed
166.-Mutants of
Agrobacterium tumefaciens auxotrophic for
adenine ,
methionine , or
asparagine are less infectious than the wild - type
strain B6 from which they were derived and show increased infectivity on
pinto bean leaves when the specific compounds required for growth of the mutants are added to the infected leaf . -
pubmed
[
Intracranial hemorrhages in
children in computerized - tomographic image ] . -
pubmed
Consequently , an analysis of the medical records of 110
patients with biopsy proven
squamous carcinoma originating in the retromolar trigone , seen and treated entirely at The University of Texas M.D. -
pubmed
Thirty - six
patients developed a second primary
cancer of which 29 were in the upper aerodigestive tract . -
pubmed
[ Curative action of
mezlocillin on experimental
infections in
mice ( author 's transl ) ] . -
pubmed
The curative action of
mezlocillin on 10 severe experimental
infections in
mice was determined and expressed as effective dose 50 ( ED50 ) . -
pubmed
Infections due to
Proteus mirabilis and
Klebsiella pneumoniae were the least susceptible to
mezlocillin . -
pubmed
For
strains of 3 species (
S. - pubmed
[ Studies on the mechanism of the development of
bronchial asthma due to
Candida albicans . -
pubmed
Postoperative
fever was the presenting symptom in 19
patients . -
pubmed
Jaundice occurred in 19
patients after a mean latent period of 8 days . -
pubmed
Sixteen
patients had been previously exposed to
enflurane or
halothane , and the latent period from exposure to the onset of symptoms or
jaundice was shortened in these
patients . -
pubmed
Due to the early nuclide excretion with an advanced secretion peak it is no longer acceptable to use a 2 - minute calculation interval for
hydronephrotic kidneys in
dogs . -
pubmed
A 57 - year - old
psoriatic man had severe , isolated
pulmonic regurgitation , with intractable right sided failure . -
pubmed
Prednisone is the recommended treatment for
patients with complete facial
paralysis ; occasionally , selected
patients may require surgical decompression . -
pubmed
Hyperresponsiveness of
migraine patients to
bromocriptine . -
pubmed
Plasma concentrations of
digoxin and
quinidine were measured ; in three of the seven
dogs ECG and physical signs of
digitalis toxicity were evaluated . -
pubmed
On the days that
digoxin was administered without
quinidine , none of the
dogs vomited nor was anorectic ; the PQ - interval increased significantly ( P less than 0.01 ) between 0.01 and 0.03 s. When
quinidine was added ,
vomiting and
anorexia occurred but no further increases in the PQ - interval were seen . -
pubmed
METHODS : Cases were obtained from Mohs - referred
basal cell carcinoma patients . -
pubmed
Caffeine consumption was higher in the
cancer patients . -
pubmed
Electrophysiological evaluation of
moricizine in
patients with sustained
ventricular tachyarrhythmias : low efficacy and high incidence of
proarrhythmia . -
pubmed
In
patients with history of sustained
ventricular tachycarrhythmias , the efficacy and safety of
moricizine have not been systematically evaluated by electrophysiological studies . -
pubmed
The study population comprised of 31
patients with clinically sustained
ventricular tachyarrhythmia . -
pubmed
The underlying
heart disease was coronary in 25
patients ,
cardiomyopathy in 5
patients , and none in 1
patient . -
pubmed
During the baseline drug - free electrophysiological testing , sustained
ventricular tachycardia was inducible in 27
patients ,
ventricular fibrillation in 1
patient , and reproducible , nonsustained
ventricular tachycardia ( 15 - 25 sec ) in 3
patients . -
pubmed
Six
patients developed
ventricular proarrhythmia within the first 4 days . -
pubmed
Proarrhythmia required multiple cardioversions in three
patients , was not associated with
QT prolongation , and spontaneously resolved 6 - 24 hours after withdrawal of
moricizine . -
pubmed
Four noninducible
patients , two
patients with inducible but slowed
VT and one
patient who had refused further testing were discharged on
moricizine.(ABSTRACT TRUNCATED AT 250 WORDS ) -
pubmed
The differential capacity of glucocorticoids and
progestins to alter chromatin structure and induce gene expression in
human breast cancer cells . -
pubmed
Reactivity of
neuroborreliosis patients (
Lyme disease ) to
cardiolipin and
gangliosides . -
pubmed
Reimplantation or allotransplantation of the immature
porcine left lower lobe results in long - term functional dynamic
airway obstruction that is associated with abnormally small distal airways . -
pubmed
METHODS : Seventy - six eyes in 41
patients were treated for
acute retinopathy of prematurity from January 1991 to April 1994 . -
pubmed
The sequences show similarity to several
bacterial antibiotic resistance proteins , further supporting a role in detoxification and possibly
Parkinson ' s disease . -
pubmed
Glycated proteins as indices of glycaemic control in
diabetic patients with
chronic renal failure . -
pubmed
Twenty uraemic
diabetic patients took part in the study , including 5
patients managed conservatively , 6 on CAPD , 3 on haemodialysis , and 6 renal transplant recipients . -
pubmed
Results were compared with those from 15
diabetic subjects with normal renal function . -
pubmed
Fructosamine correlated significantly with mean blood
glucose concentrations measured over the previous week in
patients with normal renal function ( r = 0.75 ; p = 0.001 ) , but not in
patients with
chronic renal failure ( r = -0.1 ; p = 0.71 ) . -
pubmed
The use of
fructosamine can not be recommended as an index of glycaemic control in
uraemic patients . -
pubmed
The authors describe a case of a
patient suffering from
Wegener ' s disease with endobronchial manifestations which progressively developed
tracheal stenosis which was not accessible to the usual immunodepressive therapy . -
pubmed
A 2 - year - old
child fell on a toothbrush , sustaining a
pharyngeal injury . -
pubmed
Oxidative organ damage in a
rat model of
thermal injury : the effect of
cyclosporin A. -
pubmed
Animal models of
thermal trauma implicate
oxygen radicals as a causative agent in local
wound response , development of
burn shock and
distant organ injury . -
pubmed
This study aimed to assess the role of neutrophils in the early and late phases of
burn injury in
rats with second - degree
skin burn . -
pubmed
Any
patient with TYPE I SSEP changes had a new postoperative
neurological deficit . -
pubmed
In
patients with
end - stage lung disease , lung transplantation can be considered the only possibility of increasing pulmonary functional capacity . -
pubmed
Selenate- and
selenomethionine - induced
leukopenia in
ICR female mice . -
pubmed
The
leukopenia was more extensive and of a greater duration for
selenomethionine - treated
mice . -
pubmed
OBJECTIVE : To describe the presence of crystalline opacities located at the level of the inner retina in
patients with chronic
retinal detachment . -
pubmed
METHODS : We reviewed the clinical records , fundus photographs , and
fluorescein angiograms of
patients with superficial retinal crystals in the presence of a chronic
retinal detachment . -
pubmed
RESULTS : Eleven eyes in 11
patients with chronic
retinal detachment were found to have these peculiar crystalline opacities on the inner retinal surface . -
pubmed
The purpose of this study was to determine whether
obese Zucker
rats responded behaviorally and metabolically to intracerebroventricularly ( i.c.v . ) -
pubmed
We found that both lean and
obese Zucker
rats had similar
body weight and food intake responses when administered a single i.c.v . -
pubmed
A decision analysis of the effect of avoiding axillary lymph node dissection in low risk
women with invasive
breast carcinoma . -
pubmed
BACKGROUND : Evidence that avoiding axillary lymph node dissection ( AxD ) strikes an appropriate balance between morbidity and recurrence risk in
patients with invasive
breast carcinoma generally is anecdotal and without a formally quantified basis . -
pubmed
METHODS : To derive quantitative estimates of the effect of avoiding
AxD on 5 - year DFS , the authors examined outcomes for
women undergoing 2 treatment scenarios : AxD or no AxD with adjuvant therapy decisions based on risk factors in the primary
tumor . -
pubmed
Eligible
patients belonged to 2 lymph node
metastases risk groups : low (
patients without palpable lymph nodes and lymphatic or vascular invasion [ LVI ] negative
tumors & lt ; or = 0.5 cm in greatest dimension ) and moderate ( patients with mammographically detected , LVI negative
tumors , between 0.6 - 2.0 cm in greatest dimension or
patients with palpable LVI negative
tumors between 0.6 - 1.0 cm in greatest dimension with nonpalpable lymph nodes ) . -
pubmed
RESULTS :
Patients in the low risk group had a 5 % risk of lymph node
metastases . -
pubmed
Patients in the moderate risk group had a 10 % risk of lymph node
metastases . -
pubmed
Eliminating AxD and treating only those
women with Grade 3
tumors & gt ; 1 cm in greatest dimension with chemotherapy and/or
tamoxifen resulted in a 1.8 % decrease in the 5 - year DFS rate . -
pubmed
CONCLUSIONS : In
patients with a low risk of lymph node
metastases , it was estimated that eliminating
AxD may result in only minimal changes in the estimated 5 - year DFS rate . -
pubmed
In search of genetic factors causing elevated levels of total
homocysteine in plasma ( tHcy ) , we investigated a cohort of consecutively identified , unrelated
thrombosis patients ( n = 28 ) having intermediate or severe
hyperhomocysteinemia ( 30 micromol / l<tHcy & lt ; or = 100 micromol / l , and tHcy & gt ; 100 micromol / l , respectively ) . -
pubmed
Coxsackievirus B3 (
CVB3 ) is a common
human pathogen that has been associated with serious diseases including
myocarditis and
pancreatitis . -
pubmed
To better understand the effect of cytotoxic T - lymphocyte ( CTL ) responses in controlling
CVB3 infection , we have inserted well - characterized CTL epitopes into the
CVB3 genome . -
pubmed
In this study , we cloned major histocompatibility complex class I - restricted CTL epitopes from
lymphocytic choriomeningitis virus (
LCMV ) into recombinant
CVB3 ( rCVB3 ) . -
pubmed
rCVB3 replicated to high titers in vivo and caused severe
pancreatitis but minimal
myocarditis . -
pubmed
In contrast , rCVB3
infection of
LCMV - immune
mice resulted in direct ex vivo cytotoxic activity against target cells coated with the epitope peptide , demonstrating that the rCVB3 - encoded
LCMV - specific epitope was expressed and presented in vivo . -
pubmed
Oxaceprol , an atypical inhibitor of
inflammation , reduces leukocyte adherence in
mouse antigen - induced
arthritis . -
pubmed
Since the exact mechanism of action remains unclear , the aim of our study was to investigate the leukocyte - endothelial cell interactions in
oxaceprol - treated
mice with antigen - induced
arthritis (
AiA ) using intravital microscopy . -
pubmed
In our study , Balb / c
mice were allocated to 4 groups ( n 7 , 8 , 8 , 8) : 2 control groups with saline or
oxaceprol and 2 groups of
arthritic animals which received saline or
oxaceprol ( 100 mg / kg twice a day intraperitoneally ) . -
pubmed
With an estimated 3.9 million people infected nationwide , combined with the observation that , for over 50 % of all cases of
HCV infection , a route of
infection is unknown ,
HCV will continue to be a major cause of
infectious disease related morbidity and mortality for years to come . -
pubmed
A case of
envenomation caused by the
Nemalecium lighti is described . -
pubmed
Curcumin exerts multiple suppressive effects on
human breast carcinoma cells . -
pubmed
In our study , we present experimental evidence suggesting that
curcumin exerts multiple different suppressive effects on
human breast carcinoma cells in vitro . -
pubmed
Many endoscopy staff nurses become overwhelmed by the complexity of patient management and the realm of equipment necessary in providing endoscopic therapy for
patients with
biliary and pancreatic disease . -
pubmed
Genetic regulation of
malaria infection in
humans . -
pubmed
[ Assessment of efficacy and tolerability of
mirtazapine treatment of
patients with
depression ] . -
pubmed
The paper presents results of the study on the efficacy and tolerability of
mirtazapine treatment of
patients with
depression . -
pubmed
65 out- and in -
patients with diagnosis of
depression was included . -
pubmed
OBJECTIVE : To describe the use of neuromuscular blocking agents ( NMBA ) in
critically ill children . -
pubmed
MAIN RESULTS : NMBAs were used for either short - term ( & lt;6 hrs ) or long - term
neuromuscular blockade in 6%-9 % of
patient ICU days and for long - term blockade in 14%-16 % of ventilatory support days . -
pubmed
Myopathy after long - term use of
NMBA was seen in only 1
patient ( 0.4 % ) . -
pubmed
CONCLUSIONS : Use of
NMBA is more common in
critically ill children than in reported studies of
critically ill adults . -
pubmed
Use of
NMBA in
critically ill children is associated with high severity of illness and mortality rates . -
pubmed
[ On the problem of occupational
Coxiella burnetii infections in
human subjects ] . -
pubmed
The distribution of
Staphylococcus aureus in hospital
infections and epidemics related to special phage - types . -
pubmed
Suprarenal stent grafting , recently modified from conventional infrarenal stent grafting , is a technique for the purpose of treating
patients with inappropriate
aneurysm necks . -
pubmed
HIV and
STD risk behavior among 18- to 25 - year - old men released from U.S. prisons : provider perspectives . -
pubmed
It might be associated with considerable improved survival rate for
liver failure patients . -
pubmed
Retinoic acid induces growth arrest and differentiation in
B16 mouse melanoma cells . -
pubmed
Eighteen
patients suffering of
retinoblastoma during three years period ( 1999 - 2001 ) were treated in two departments of ophthalmology in the Czech Republic . -
pubmed
We conclude that
intracranial chondroma should be included in the differential diagnosis of a calcified mass for the
patients who had had a compound , depressed
skull fracture along the suture line , especially in cases of
dural laceration by the fragmented bone . -
pubmed
Reduced
D - serine to total
serine ratio in the cerebrospinal fluid of drug naive
schizophrenic patients . -
pubmed
METHODS : Liver samples of 12
patients undergoing autopsy , liver transplantation , or
liver tumor resection were investigated . -
pubmed
Sections & gt;1 cm(2 ) and stained by Sirius red were used for the reference staging of
liver fibrosis in each
patient according to the METAVIR scoring system . -
pubmed
Objective B wave analysis in 55
patients with non - communicating and communicating
hydrocephalus . -
pubmed
OBJECT : To determine the relation between the percentage of B waves and outcome in
patients with
hydrocephalus , and also the diurnal variation of B waves . -
pubmed
METHODS : ICP and
patient behaviour were recorded overnight ( 17 to 26 hours ) in 29
patients with non - communicating
hydrocephalus and 26 with
NPH . -
pubmed
The percentage of B waves was the same during sleep and wakefulness , and
patients with
NPH had the same proportion of B waves as the non - communicating
patients . -
pubmed
CONCLUSIONS : B waves are commonly observed in
patients with both communicating and non - communicating
hydrocephalus , but are only weakly related to the degree of postsurgical improvement . -
pubmed
Preoperatively a total of 22 tubes were inserted in 13
patients to overcome
urinary obstruction . -
pubmed
A total of 24 transurethral prostatic
tumor resections were performed in 11
patients . -
pubmed
[ Combined effect of
micafangin and
itraconazole on severe
aspergillosis of the bilateral pleural cavities in a
patient with
Wegener ' s granulomatosis ] . -
pubmed
Here we report that combined use of two antifungal agents (
micafangin and
itraconazole ) was effective against severe
aspergillosis of the bilateral pleural cavities in a 48 - year old male
patient diagnosed with
Wegener ' s granulomatosis . -
pubmed
Aspergillus fumigatus then infected the bilateral pulmonary cavities through these
fistulas . -
pubmed
This patient was treated with combined therapy of
ITCZ and
MCFG was given to this
patient because of the risk of
renal dysfunction associated with
AMPH - B. -
pubmed
RESULTS : Although similar with regard to age and sex ,
patients with
diabetes more often had pre - existing
cardiovascular and renal disease and
heart failure as the cause of acute
dyspnoea compared with patients without
diabetes . -
pubmed
In addition , medical and economic outcomes were worse in
patients with
diabetes . -
pubmed
Laparoscopic cecostomy button placement for the management of
fecal incontinence in
children with
Hirschsprung ' s disease and
anorectal anomalies . -
pubmed
BACKGROUND : Antegrade colonic enemas offer a surgical solution for many
children with chronic
constipation and
encopresis associated with
Hirschsprung ' s disease and
anorectal malformations . -
pubmed
METHODS : Charts of
children with
encopresis who underwent LCBP between 1999 and 2001 were reviewed . -
pubmed
Four
patients had
anorectal malformations , and three
patients had
Hirschsprung ' s disease . -
pubmed
For all the
patients , LCBP was accomplished without any
intraoperative complications . -
pubmed
Episodes of
soiling at night once or twice a week were observed with two
children . -
pubmed
Two
patients had
hypertrophic granulation tissue formation , which responded to topical therapy . -
pubmed
CONCLUSION : To manage
overflow incontinence of
children with
anorectal malformations and
Hirschsprung ' s disease , LCBP is a technically straightforward , effective , and reversible method for the placement of a cecostomy button . -
pubmed
Erythrocytes from twenty nine consecutive
patients with
rheumatoid arthritis ( 11
men , 18
women ) aged 54 years were obtained . -
pubmed
Patients with
rheumatoid arthritis were subdivided into two groups twice : with active disease ( 18
patients ) and in remission ( 11
patients ) , and secondly into
patients receiving ( 21 subjects ) and not receiving ( 8 subjects ) non - steroidal anti - inflammatory drugs . -
pubmed
It seems HSW balneum produce an antioxidant effect on erythrocyte status in
patients with
rheumatoid arthritis . -
pubmed
Influence of disease stage on
polyethylenimine - mediated plasmid DNA delivery in
murine hepatitis . -
pubmed
In order to determine the influence of
hepatic disease - stage on
polyethylenimine - mediated gene delivery , we investigated branched and linear
polyethylenimine (
B - PEI , L - PEI)-mediated plasmid DNA delivery with time in
murine hepatitis induced by a subcutaneous injection of
tetrachloro carbon (
CCl ( 4 ) ) . -
pubmed
Significant differences in gene expressions between
CCl ( 4 )-treated
mice and control
mice vanished in most organs at the
hepatitis subsidence stage ( 168 h after
CCl ( 4 ) injection ) , indicating that the influence of
hepatitis induced by
CCl ( 4 ) was reversible with
PEI - mediated gene delivery . -
pubmed
Our findings demonstrated that
murine hepatitis induced by
CCl ( 4 ) could influence
polyethylenimine - mediated plasmid DNA delivery according to the disease stage . -
pubmed
Accordingly , the aim of this study was to investigate measures of
insulin sensitivity , the
metabolic syndrome , and sex hormones in
patients with
Klinefelter ' s syndrome and an age - matched control group . -
pubmed
RESEARCH DESIGN AN METHODS : In a cross - sectional study , we examined 71
patients with
Klinefelter ' s syndrome , of whom 35 received
testosterone treatment , and 71 control subjects . -
pubmed
We analyzed differences between
patients with untreated
Klinefelter ' s syndrome and control subjects and subsequently analyzed differences between
testosterone - treated and untreated
Klinefelter ' s syndrome patients . -
pubmed
RESULTS : Of the
patients with
Klinefelter ' s syndrome , 44 % had
metabolic syndrome ( according to National
Cholesterol Education Program / Adult Treatment Panel III criteria ) compared with 10 % of control subjects . -
pubmed
This review considers the
animal and
human evidence that lead exposure can produce a stark shift in immune functional capacity with a skewing predicted to elevate the risk of atopic and certain
autoimmune diseases . -
pubmed
METHODS : A clinical database and a severity scale was created to evaluate 45
patients diagnosed with
Niemann - Pick type C in the last 28 years in Spain . -
pubmed
Splenomegaly was present in 28
patients ( 93 % ) with a wide range of age at detection . -
pubmed
Diagnosis was made before the onset of neurological signs in
patients with the severe infantile form , at the time of onset of cerebellar signs in the late infantile form and complete
ophthalmoplegia in late onset forms . -
pubmed
CONCLUSIONS : In our series ,
splenomegaly is present in 96 % of
patients , even in late onset forms during the first years of life . -
pubmed
Clumsiness in
children with otherwise normal motor development precedes the onset of
ataxia by 2 - 4 years in
Niemann Pick type C. -
pubmed
PATIENT(S ): Seventy - three
women with
menorrhagia . -
pubmed
The remaining five
women requested the procedure be stopped because of
pain . -
pubmed
Significantly fewer
women in the outpatient group experienced
nausea ( 13 % versus 65 % in the daycase group ) or
vomiting ( 0 versus 24 % in the daycase group ) , or required postoperative antiemetics ( 0 versus 56 % in the daycase group ) . -
pubmed
Differential responses to anxiogenic drugs in a
mouse model of
panic disorder as revealed by Fos immunocytochemistry in specific areas of the fear circuitry . -
pubmed
Sensitivity to pharmacological challenges has been reported in
patients with
panic disorder . -
pubmed
Identification of
Phytophthora sojae genes upregulated during the early stage of
soybean infection . -
pubmed
sojae genes that are differentially expressed in the early stage of
Glycine max (
soybean )
infection . -
pubmed
This report presents a natural history of a
patient with low grade
astrocytoma . -
pubmed
The described
patient with low - grade
astrocytoma lived without any oncological treatment eight years and four months from the time when diagnosis was made until
intracranial herniation . -
pubmed
The natural history of disease in presented
patient indicated that rational therapeutic strategy , for low - grade
astrocytoma with
epilepsy only , would be deferral of surgery until the time of manifestation of neurological or radiological deterioration . -
pubmed
CASE - REPORT : A 34 - year - old
patient presented with intraoral ulcerating , necrotizing
inflammations of the palate and the gingiva . -
pubmed
The
patient died of
cardiac decompensation three months after diagnosis . -
pubmed
Behaviorally , 2 microL and 8 microL ZG - treated
mice and those given multiple injections of 2 microL ZG performed as well as controls , whereas those given 50 microL were
hyposmic but not anosmic . -
pubmed
ZS - treated
mice performed more poorly , and those injected with 50 microL were
anosmic for the first 8 to 10 test days . -
pubmed
Leuprorelin acetate every-3 - months depot versus
cyclophosphamide ,
methotrexate , and
fluorouracil as adjuvant treatment in premenopausal
patients with node - positive
breast cancer : the TABLE study . -
pubmed
RESULTS : With a median follow - up of 5.8 years ,
recurrence - free survival was similar for
patients treated with LAD-3 M or
CMF ( hazard ratio [ HR ] , 1.19 ; 95 % CI , 0.94 to 1.51 ; P = .15 ) . -
pubmed
The purpose of this study was to analyze the incidence and laterality of
astigmatism in
children with
unilateral coronal synostosis . -
pubmed
METHODS : We retrospectively reviewed the charts of 39 consecutive
patients with unilateral
coronal synostosis . -
pubmed
Recorded data included the following :
patient demographics , visual acuity , cycloplegic refraction , ocular motility , procedures for craniofacial and
strabismus correction , and presence and treatment of
amblyopia at each visit . -
pubmed
RESULTS : Twenty - one of 39
patients ( 54 % ) had 1.00 D or more
astigmatism in at least one eye at their last recorded refraction . -
pubmed
Fifteen of the 39 studied ( 38 % ) had
amblyopia and , in 12 of these 15
patients ( 80 % ) , the
amblyopic eye was contralateral to the
synostosis . -
pubmed
Nineteen of 39
patients ( 49 % ) had greater
ipsilateral fundus excyclotorsion , whereas only 1 of 39 ( 3 % ) had greater
contralateral excyclotorsion . -
pubmed
CONCLUSIONS :
Patients with
unilateral coronal synostosis are at risk for developing a greater degree of
astigmatism in the eye contralateral to the
synostosis . -
pubmed
Ocular disturbances in the contralateral eye , especially
anisometropic amblyopia , must be considered when treating
patients with this type of
craniosynostosis . -
pubmed
We examined ( 1 ) microstructural changes of white matter ( WM ) adjacent to supratentorial
low grade tumors in
children and ( 2 ) WM tracts of the affected hemisphere using diffusion tensor imaging ( DTI ) . -
pubmed
MATERIALS AND METHODS : DTI was performed in 11
children with
low grade tumors diagnosed by magnetic resonance imaging ( MRI ) . -
pubmed
CONCLUSION : We found preserved microstructural integrity of WM adjacent to
low grade tumors in
children . -
pubmed
PURPOSE : To review the assessment , diagnosis , and management of
hyponatremia ( serum
sodium & lt;135 mEq / L ) , the most common
electrolyte disturbance as a result of dysregulation of water balance in hospitalized or institutionalized
patients . -
pubmed
CONCLUSIONS : A diagnosis of
hyponatremia requires thorough investigation for underlying causes and prompt treatment to prevent poor
patient outcomes . -
pubmed
Among this class of agents , intravenous
conivaptan hydrochloride , indicated for the treatment of euvolemic
hyponatremia in hospitalized
patients , is the first drug in class approved for use . -
pubmed
IMPLICATIONS FOR PRACTICE : Elderly
patients , and those with certain conditions such as
heart failure ,
tuberculosis ,
cirrhosis , and
head injury , may be at increased risk for
hyponatremia . -
pubmed
In hospitalized
patients following surgery and the use of certain medications ,
hyponatremia is a common condition . -
pubmed
Awareness of the limitations of conventional therapies and the availability of new treatment options for
hyponatremia allows clinicians to optimize
patient care . -
pubmed
OBJECTIVE : To examine performance of transcranial motor - evoked potential ( TcMEP ) monitoring in
patients undergoing surgery for
cervical myelopathy and potential risk factors for false positive alerts . -
pubmed
SUMMARY OF BACKGROUND DATA : Although use of TcMEP monitoring has been increasing and has been specifically recommended in
patients with
cervical myelopathy , rates and risk factors for false positive alerts have not been established . -
pubmed
METHODS : Intraoperative neuromonitoring data for 52 consecutive
patients undergoing surgery for
cervical myelopathy were reviewed . -
pubmed
No new postoperative
neurologic deficits were observed in these
patients . -
pubmed
One
patient with new postoperative
weakness was correctly predicted by loss of TcMEP signals . -
pubmed
CONCLUSION : In this series of
cervical myelopathy patients , sensitivity and specificity of TcMEP for detection of clinically significant
intraoperative cord injury were 100 % and 90 % , respectively . -
pubmed
The success of
warfarin treatment for
coronary thrombosis in a young
patient with
acute coronary syndrome . -
pubmed
Using the chemical mammary
carcinogenesis model of
human c - Ha - ras transgenic ( Tg ) rats , we confirmed that parity protected the mammary glands at the postinitiation phase of
tumorigenesis . -
pubmed
Although the incidence of
7,12 - dimethylbenz [ alpha ] anthracene - induced palpable
tumors was reduced from 61.5 % in the AMV Tg
rats to 28.5 % in the parous
animals , the incidence of early
neoplastic lesions in the parous
rats was the same as that in the AMV
rats . -
pubmed
PATIENTS AND METHODS : 37
patients with clinically suspected
NPH were included in the study . -
pubmed
Analysis of neuronal cell
death in the cerebral cortex of H - Tx
rats with compensated
hydrocephalus . -
pubmed
METHODS : The cerebral cortices of 8 - week - old H - Tx
rats with spontaneously arrested
hydrocephalus ( hH - Tx ) and nonhydrocephalic H - Tx ( nH - Tx ) control
rats were subjected to cDNA microarray analysis followed by canonical pathway analysis . -
pubmed
OBJECTIVE : This experimental , repeated - measures , crossover design study with nursing home
residents examined the efficacy of reflexology in individuals with mild - to - moderate stage
dementia . -
pubmed
SAMPLE : The sample included 21 nursing home
residents with mild - to - moderate stage
dementia randomly assigned to two groups . -
pubmed
CONCLUSIONS : This study provides preliminary support for the efficacy of reflexology as a treatment of stress in nursing home
residents with mild - to - moderate stage
dementia . -
pubmed
SCA3 : neurological features , pathogenesis and
animal models . -
pubmed
METHODS : 161
critically ill patients requiring dialysis for
ARF were analyzed . -
pubmed
Patient demographics , comorbid conditions ,
ARF etiology , mode of renal replacement therapy ( RRT ) , renal recovery , and survival were abstracted from medical chart . -
pubmed
Splenic erythroblasts were obtained from
mice during the
acute disease caused by anemiainducing virus ( FVA ) . -
pubmed
METHODS : We conducted a case - control study of
esophageal cancer patients from two centers , comparing cases with lung
metastases to controls without lung
metastases . -
pubmed
Among
patients with lung
metastases , 73.6 % ( 39 of 53 ) were ever smokers , versus 47.8 % ( 144 of 301 ) of patients without lung
metastases [ P=0.001 ; summary odds ratio ( OR ) , 2.52 ; 95 % confidence interval ( 95 % CI ) , 1.17 - 5.45 ; stratified by histology ] . -
pubmed
We report a
patient with
pulmonary embolism , dissection in the descending and abdominal aorta , and persistent left superior vena cava . -
pubmed
The
cancer resistance is transferable to other
strains of
mice by adoptive transfer of innate immune cells . -
pubmed
Serologic response to
hepatitis B vaccine with high dose and increasing number of injections in
HIV infected adult patients . -
pubmed
In this chapter , we describe techniques used to determine the efficiency of hepatocyte transplantation in
animal models of
liver disease . -
pubmed
Protocols for the collection of bile in
rats and
mice are described , and we have also detailed the detection of green fluorescent protein ( GFP)-labelled
human hepatocytes in
immunodeficient mice in this chapter . -
pubmed
PURPOSE : Describing the ophthalmic findings of an
exudative vasculopathy called as
Coats - like retinitis pigmentosa on three
patients . -
pubmed
RESULTS : We have identified 3
patients who have some typical clinical features of
Coats - like retinitis pigmentosa ; peripheral serous
retinal detachment ,
telangiectasia , prominent lipid deposition ,
pigmentary changes in peripheral retina , and
loss of vision . -
pubmed
None of the three
patients had
positive family history . -
pubmed
All of the
patients have had symptoms of
nyctalopia ,
decreased central vision , and two of them have had constriction of visual field . -
pubmed
All of the
patients have had
cataracts and two of them underwent
cataract surgery . -
pubmed
Fundus examination and
fluorescein angiography of
patients revealed typical
retinitis pigmentosa with Coats - type changes in bilateral inferiotemporal quadrants . -
pubmed
Aclidinium bromide provides long - acting bronchodilation in
patients with
COPD . -
pubmed
A total of 464
patients with moderate to severe stable
COPD were randomised to double - blind , once - daily treatment with
aclidinium ( 25 , 50 , 100 , 200 , or 400microg ) , placebo , or open - label
tiotropium ( 18microg ) for 4 weeks . -
pubmed
METHOD : Thirty - three
patients ( 17 with mild
ID and 16 with moderate to severe
ID ) discharged between 2006 and 2008 from a specialised inpatient unit in Canada for adults with
ID and
mental illness were studied . -
pubmed
However , only
patients with mild
ID demonstrated improvements on the Global Assessment of Functioning . -
pubmed
Important differences between Fontan
patients and controls were seen in several vascular compartments : ( 1 ) Calf capacitance was lower ( median , 3.5 versus 5.5 mL/100 mL tissue ; P=0.005 ) , and resting venous pressure was higher ( 13.0 versus 10.5 mm Hg ; P=0.004 ) ; ( 2 ) higher leg arterial resistance was observed ( 32.1 versus 22.2 ; P=0.03 ) ; ( 3 ) microvascular filtration pressures and threshold for
edema were elevated ; and ( 4 ) with head - up tilt testing , splanchnic flow was not reduced in Fontan
patients versus controls ( fractional change , +4 % versus -32 % ; P=0.004 ) , and splanchnic arterial resistance did not increase as expected ( fractional change , +8 % versus +79 % ; P=0.003 ) . -
pubmed
The results in 5 eyes of 5
patients with
aphakic bullous keratopathy and lack of capsule support are reported . -
pubmed
We speculate that these SNPs may compromise mammary cell function , which may have important implications in
human health and
breast disease . -
pubmed
The Substance Abuse and Mental Health Services Administration ( SAMHSA ) in the US Department of Health and
Human Services is uniquely positioned to help develop national mental health policies that promote mental health and prevent
mental illnesses . -
pubmed
Somatic mutations in single network components lead to changes in transport dynamics that may contribute to pathological modifications underlying several
human diseases such as
mental retardation . -
pubmed
Oral probiotics :
Lactobacillus sporogenes for prevention of
necrotizing enterocolitis in very low -
birth weight infants : a randomized , controlled trial . -
pubmed
Lactobacillus sporogenes has not been used in the prevention of
NEC in very low -
birth weight infants yet . -
pubmed
The objective of this study was to evaluate the efficacy of orally administered
L sporogenes in reducing the incidence and severity of
NEC in very low -
birth weight ( VLBW ) infants . -
pubmed
SUBJECTS / METHODS : A prospective , blinded , randomized controlled trial was conducted in preterm infants with a gestational age of & lt;33 weeks or
birth weight of & lt;1500 g. VLBW infants who survived to start enteral feeding were randomized into two groups The infants in the study group were given
L. - pubmed
We investigated the teratogenic agent
phenytoin and extract of the immunostimulant
Echinacea purpurea in the etiology of
cleft palate associated with the proliferation and apoptosis of
mouse embryonic palatal mesenchymal ( MEPM ) cells . -
pubmed
The teratogenic effect of
phenytoin on
cleft palate is associated with the proliferation and apoptosis of MEPM cells , and
E. - pubmed
PATIENTS : Six high - level rock climbers with
SLAP lesions and
degeneration of the long biceps tendon anchor or additional pulley lesions were surgically treated with primary tenodesis . -
pubmed
We report isolation of
Histoplasma capsulatum from the blood of an
AIDS patient . -
pubmed
Aging and antihypertensive medication - related complications in the
chronic kidney disease patient . -
pubmed
PURPOSE OF REVIEW : We have reviewed the recent literature to describe the potential medication errors and
adverse drug events ( ADEs ) associated with antihypertensives among older
adults with
chronic kidney disease (
CKD ) . -
pubmed
RECENT FINDINGS : Overall , few studies have been published describing ADEs in older
adults with
CKD . -
pubmed
SUMMARY : Some of the most common ADEs associated with antihypertensive use in older
adults with
CKD include
hyperkalemia ,
AKI , and
orthostatic hypotension . -
pubmed
Treatment of
HEY xenograft - bearing mice with
dasatinib plus
paclitaxel inhibited
tumor growth more than treatment with either agent alone ( average
tumor volume per
mouse ,
dasatinib +
paclitaxel vs
paclitaxel : 0.28 vs. 0.81 cm3 , difference = 0.53 cm3 , 95 % confidence interval [ CI ] = 0.44 to 0.62 cm3 , P = .014 ) ;
dasatinib +
paclitaxel vs.
dasatinib : 0.28 vs. 0.55 cm3 , difference = 0.27 cm3 , 95 % CI = 0.21 to 0.33 cm3 , P = .035 ) . -
pubmed
JPH203 was intravenously administered to produce significant growth inhibition against
HT-29 tumors transplanted in
nude mice . -
pubmed
Microarray meta - analysis defines global angiogenesis - related gene expression signatures in
human carcinomas . -
pubmed
BACKGROUND : The correlation between the number of pathologic metastatic LNs in
patients with
esophageal squamous cell carcinoma (
ESCC ) after neoadjuvant chemoradiotherapy ( NACRT ) and surgical outcome has rarely been reported . -
pubmed
METHODS : Eighty - eight
patients with
ESCC who underwent NACRT followed by surgery were evaluated . -
pubmed
According to the number of metastatic LNs , the difference in the median survival was the largest between the groups when
patients were divided into those with 2 and 3 metastatic
LNs ( chi(2 ) : 13.694 , P & lt ; 0.001 ) . -
pubmed
The purpose of this systematic review was to investigate the effects of therapeutic radiopharmaceuticals in
patients with different types of advanced
neuroendocrine tumour (
NETs ) . -
pubmed
The severe
toxicities for
( 177 ) Lu - DOTATATE included
hepatic insufficiency in 0.6 % ,
myelodysplastic syndrome in 0.8 % and
renal insufficiency in 0.4 % of
patients in this study . -
pubmed
Insufficient evidence suggested efficacy of
( 131 ) I - MIBG in adult
NET patients , but the overall
tumour response rate from
( 131 ) I - MIBG was 27 - 75 % for
malignant neuroblastoma ,
paraganglioma or
pheochromocytoma . -
pubmed
Haematological
toxicities were the main severe side - effects after
( 131 ) I - MIBG and 4 % of
patients developed secondary
malignancies in one study . -
pubmed
The virus is associated with respiratory problems in
pigs of all ages and is commonly isolated on farms with
porcine respiratory disease complex (
PRDC ) . -
pubmed
Due to virus - induced macrophage
death early in
infection ,
PRRSV hampers the innate defence against pathogens in the lungs . -
pubmed
Similar results were obtained using inactivated
PRRSV (
LV ) , showing that initial interaction of the virion with the cell is sufficient to reduce phagocytosis , and that no productive
infection is required . -
pubmed
We identified 47
patients with
spina bifida ( median age at followup 26.8 years ) who underwent either enterocystoplasty or detrusorectomy between 1988 and 2004 . -
pubmed
The relationships between genome wide association study - identified and replicated genetic variants associated with
Alzheimer ' s disease (
AD ) risk and
disease progression or therapeutic responses in
AD patients are almost unexplored . -
pubmed
We studied 59
patients with
idiopathic dilated cardiomyopathy who had a potential clinical and echocardiographic follow - up period of & gt;12 years . -
pubmed
Of the 59
patients , 38 died (
heart failure in 20 ,
sudden death in 11 , and other causes in 7 ) , 2 underwent transplantation , and 19 survived . -
pubmed
Of the 1,000
patients , 82 were excluded owing to negative or interval appendectomy or advanced
end - stage renal disease . -
pubmed
Glucocorticoid - induced changes in gene expression of airway smooth muscle in
patients with
asthma . -
pubmed
METHODS : Twelve
steroid - free
patients with
atopic asthma were included in this double - blind intervention study . -
pubmed
OBJECTIVE : To evaluate the association between severity of
cerebral palsy (
CP ) and growth to 6 to 7 years of age among
children with moderate to severe ( Mod / Sev )
hypoxic ischemic encephalopathy (
HIE ) . -
pubmed
It was hypothesized that
children with Mod / Sev
CP would have poorer growth , lower cognitive scores , and increased rehospitalization rates compared with children with no
CP ( No
CP ) . -
pubmed
METHODS : Among 115 of 122 surviving
children followed in the
hypothermia trial for neonatal
HIE , growth parameters and neurodevelopmental status at 18 to 22 months and 6 to 7 years were available . -
pubmed
The control group was consisted of
patients who underwent arthroscopic surgery for other reasons than
cartilage disorders . -
pubmed
In the
osteoarthritis group all
patients had grade 4 primer degenerative
osteoarthritis and were treated with total knee arthroplasty . -
pubmed
This study proposes to establish data - driven criteria for the use of CXR as a diagnostic modality in the preoperative evaluation of
patients with
PE . -
pubmed
METHODS : A total of 57 consecutive
patients with
ascites requiring a large volume paracentesis were studied . -
pubmed
A 74 - year - old
man presents with a
left upper lobe lung adenocarcinoma , which demonstrated a wide base intimately with the aortic arch . -
pubmed
Asymmetric dimethylarginine levels in
patients with
cutaneous anthrax : a laboratory analysis . -
pubmed
The aim of the study was to investigate the serum
ADMA levels in
patients with
CA . -
pubmed
METHODS : A total of 35 serum samples of the
patients with
CA and 18 control sera were tested for
ADMA levels using ADMA ELISA kit ( Immunodiagnostik AG , Bensheim , Germany ) . -
pubmed
In addition , these data might suggest the higher
ADMA levels in
patients could be due to the
perivascular inflammation and
vasculitis in
CA . -
pubmed
[ Clinical features of
rituximab plus chemotherapy as first - line treatment in
patients with
diffuse large B - cell lymphoma ] . -
pubmed
OBJECTIVE : A prospective , multicenter and non - interventional prospective study was conducted to evaluate the clinical features of
rituximab combined with chemotherapy ( R - Chemo ) as first - line treatment on newly diagnosed Chinese
patients with
diffuse large B - cell lymphoma (
DLBCL ) . -
pubmed
ECOG performance statuses of 0 or 1 were observed in 91.1 % of
patients , international prognostic index levels in the low - risk and low - middle - risk groups in 76.4 % of
patients , the
tumor diameters smaller than 7.5 cm in 69.0 % of
patients . -
pubmed
CONCLUSION : Non - interventional clinical trial of
R - Chemo remains the standard first - line treatment for newly diagnosed
patients with
DLBCL in real clinical practice , which is consistent with international treatment recommendations for
DLBCL patients . -
pubmed
R - Chemo can provide the clinical evidence and benefit as the first - line standard treatment for Chinese
patients with
DLBCL . -
pubmed
METHODS : Between November 2008 and December 2009 , 107
patients who were diagnosed as having
lung cancer or strongly suspected of having
lung cancer were enrolled . -
pubmed
RESULTS : In 100
patients , the early
( 18 ) F - FDG PET scan resulted in upstaging of the
tumor in ten ( 10 % ) and down - staging of the
tumor in five ( 5 % ) compared to the conventional scan . -
pubmed
The delayed phase of
( 18 ) F - FDG PET provided no additional information on staging for
lung cancer patients . -
pubmed
The remaining seven
patients were diagnosed as not having
lung cancer . -
pubmed
CONCLUSION : This study confirmed that dual - time - point
( 18 ) F - FDG PET is useful for differential diagnosis between benign and malignant lesions , but has no major impact on staging and therapeutic management of
patients with pathologically proven
lung cancer . -
pubmed
Most patients with
CDI had negative blood cultures or grew
Staphylococcus sp . -
pubmed
The percentages of
underweight ,
overweight and
obese patients were ; 27.3 % , 18.2 % and 3.6 % , respectively pre - MMT , and 12.7 % , 18.2 % and 7.2 % , respectively after MMT . -
pubmed
MATERIAL AND METHODS : A retrospective analysis was made of
patients treated at the Department of Head and Neck Surgery in the Greater Poland Cancer Centre of the Poznan University of Medical Sciences in 2007 - 2012 for
BCC of the head and neck region . -
pubmed
RESULTS : In the study group of 312
tumors , recurrence after initial treatment in this Centre was diagnosed in 18
patients ( 9 % ) , whereas in patients who were previously operated elsewhere ,
recurrence was found in 22 cases ( 17 % ) . -
pubmed
The nodular type was the most common
BCC type in the study group and concerned 175
patients ( 56 % ) . -
pubmed
CONCLUSIONS : The importance of preoperative biopsy to assess the histological type as a routine treatment of
patients with
BCC is essential . -
pubmed
Increased risk of
end - stage renal disease in
patients with
renal cell carcinoma : a 12 - year nationwide follow - up study . -
pubmed
Osteoarthritis (
OA ) is a
progressive joint disorder , which remains the leading cause of
chronic disability in aged
people . -
pubmed
Circulating microRNAs in
patients with
non - alcoholic fatty liver disease . -
pubmed
METHODS : Twenty
patients with histologically proven
NAFLD and 20 controls were included . -
pubmed
RESULTS : Serum levels of miR-181d , miR-99a , miR-197 and miR-146b were significantly lower in biopsy - proven
NAFLD patients than in the healthy controls . -
pubmed
CONCLUSIONS : The study results indicate that
sevoflurane , like
propofol , induces coherent frontal alpha oscillations and slow oscillations in
humans to sustain the anesthesia - induced
unconscious state . -
pubmed
Evaluation of an oral supplement containing
Phyllanthus emblica fruit extracts ,
vitamin E , and carotenoids in
vitiligo treatment . -
pubmed
Phyllanthus emblica ,
vitamin E , and
caroteinods are compounds showing antioxidative , anti - inflammatory , and repigmenting effects , whose role in
vitiligo treatment has not been evaluated so far . -
pubmed
Moreover , group B
patients showed higher signs of
inflammation ( p = 0.002 ) , a more rapid growth of the lesions ( p = 0.039 ) , a higher percentage of worsening disease ( p = 0.003 ) , and more
erythema ( p = 0.059 ) , whereas group A patients showed a higher percentage of steady disease ( p = 0.065 ) . -
pubmed
Our results suggest that the supplement with antioxidants in
patients with
vitiligo might represent a valuable instrument to increase the effectiveness of other
vitiligo treatments . -
pubmed
OBJECTIVE : The following report presents a case in which significant
clozapine toxicity was demonstrated in a
patient on established therapy , in the absence of identifiable risk factors . -
pubmed
RESULTS : We describe a case of a 62 year old
man whom developed life - threatening
clozapine toxicity in the context of a severe lower
respiratory infection . -
pubmed
Unfortunately case management in health facilities is very poor ; health facilities are few and understaffed mainly with unskilled personnel who are overburdened by other illnesses such as
malaria and
HIV and the supply of
praziquantel in health facilities is inadequate . -
pubmed
An uncommon cause of
allergic fungal sinusitis :
Rhizopus oryzae . -
pubmed
We report what we believe is the first case of
allergic fungal rhinosinusitis (
AFRS ) caused by the fungus
Rhizopus oryzae . -
pubmed
Our patient was a 32 - year - old
woman who presented with
unilateral nasal polyps and
chronic nasal dysfunction . -
pubmed
Comparative analysis with the KiGGS data ( & gt;14,000
spot urines of
children ; median UIC 117 microg / L ) revealed a comparable percentage & lt;EAR ( 33 % ) . -
pubmed
Biomechanical and Macroscopic Evaluations of the Effects of
5 - Fluorouracil on Partially Divided
Flexor Tendon Injuries in
Rabbits . -
pubmed
This study aims to develop a prognostic risk prediction model for the development of
silicosis among
workers exposed to
silica dust in China . -
pubmed
An analysis of the intervention effect of perioperative evidence - based nursing on
orthopedic trauma patients ' vagal reflex . -
pubmed
PATIENTS AND METHODS : Eighty - six
patients were selected , who were hospitalized in orthopedics department of our hospital because of
trauma from March , 2013 to March , 2014 . -
pubmed
CONCLUSIONS : EBN could reduce the prevalence of vagal reflex to some extent on perioperative
orthopedic trauma patients . -
pubmed
It is usually a diffuse , low - grade
astrocytoma ( WHO grade II ) , seen mainly in adults , with approximately 25 % of them involving
children under the age of 15 . -
pubmed
We report a 1 - year follow - up of a 55 - year - old female
patient with bilateral WHO grade II thalamic
astrocytoma . -
pubmed
The primary aim was to compare postoperative radiographic outcomes between sexes among
adolescent idiopathic scoliosis (
AIS )
patients . -
pubmed
A total of 162
AIS patients ( 42
males and 120 females ) undergoing pedicle screw instrumentation and posterior fusion were included . -
pubmed
Yet , in a significant number of
patients the transfemoral access is not suitable due to
peripheral vascular disease of the lower extremity . -
pubmed
[ Prevalence of
deep venous thrombosis in
burn patients and its influencing factors ] . -
pubmed
METHODS : Clinical data of 2 506
burn patients admitted to our ward from January 2009 to January 2014 , conforming to the study criteria , were retrospectively analyzed . -
pubmed
Patients were divided into
DVT group ( n=26 ) and non -
DVT group ( n=2 480 ) according to whether or not
DVT occurred during hospitalization . -
pubmed
Metabolic bone disease is a common complication of
PBC , affecting 14 % to 52 % of
patients , depending on the duration and severity of
liver disease . -
pubmed
Additional large prospective , long - term studies in
patients with
PBC are needed to determine efficacy in improving bone density as well as reducing
fracture risk . -
pubmed
Sheep receiving nontransfected BMMSCs ( BMMSC ; n=6 ) displayed less
infarct size limitation and percent LVEF improvement , whereas in placebo - treated
animals ( n=6 ) , neither parameters changed over time . -
pubmed
Classification of Extraovarian Implants in
Patients With
Ovarian Serous Borderline Tumors (
Tumors of Low Malignant Potential ) Based on Clinical Outcome . -
pubmed
The classification of extraovarian
disease into invasive and noninvasive implants predicts
patient outcome in
patients with high - stage ovarian serous borderline
tumors (
tumors of low malignant potential ) . -
pubmed
Peritoneal and/or lymph node implants from 181
patients with high - stage serous borderline
tumors were evaluated independently by 3 pathologists for the following 8 morphologic features : micropapillary architecture ; glandular architecture ; nests of epithelial cells with surrounding retraction artifact set in densely fibrotic stroma ; low - power destructive tissue invasion ; single eosinophilic epithelial cells within desmoplastic stroma ; mitotic activity ; nuclear pleomorphism ; and nucleoli . -
pubmed
Assessing
patient outcomes and cost - effectiveness of nurse - led follow - up for women with
breast cancer - have relevant and sensitive evaluation measures been used ? -
pubmed
Challenges in the first
seizure clinic for adult
patients with
epilepsy . -
pubmed
AIMS : ( 1 ) To delineate the challenges in
seizure diagnosis in the first
seizure clinic setting for adult
patients of a teaching hospital , and ( 2 ) quantify the diagnostic accuracy of the referral source and the yield of routine investigations , including blood tests , EEGs , and neuroimaging . -
pubmed
RESULTS : In total , 219
patients were referred to the first
seizure clinic . -
pubmed
From the cohort , 38 ( 17 % )
patients presented with
seizure mimickers ; the most common were
reflex syncope ( 74 % ) and
psychogenic non - epileptic seizures ( 16 % ) . -
pubmed
From the remaining 181
patients presenting with
seizures , only 110 ( 61 % ) of these patients were diagnosed with true first
seizures , and 71 ( 39 % ) patients had evidence of previous
seizures . -
pubmed
In our true first
seizure patients , the EEG demonstrated
epileptiform discharges in 22 ( 21 % )
patients . -
pubmed
Our data highlight the potential pitfalls and practical challenges in this process , as well as the need for these
patients to be assessed in dedicated first
seizure clinics . -
pubmed
Finally , the trajectory of
body weight changes was affected by irradiation , with lower
body weights in irradiated than sham - irradiated
mice , with the most profound effect 7days after training . -
pubmed
These data indicate that whole body X ray irradiation of
mice at 3 months of age causes persistent alterations in the fear response and activity levels in a novel environment , while the effects on
body weight seem more transient . -
pubmed
PATIENT CONCERNS : In Sep 2015 , a 59 - year - old female
patient presented to our hospital , complaining of refractory
low back pain ,
left sternoclavicular joint pain , and
palmoplanar pustulosis (
PPP ) . -
pubmed
In addition ,
RA had been diagnosed 10 years earlier in the
patient , manifested as
pain and
swelling in bilateral hands and wrists , accompanied by
morning stiffness , as well as positive serologic tests . -
pubmed
Intersexual differences of heat
shock response between two amphipods (
Eulimnogammarus verrucosus and
Eulimnogammarus cyaneus ) in Lake Baikal . -
pubmed
cyaneus females after heat
shock and recovery compared to males , which was not found for
E. - pubmed
Do bilateral and unilateral greater occipital nerve block effectiveness differ in chronic
migraine patients ? -
pubmed
We aimed to compare the effectiveness of bilateral and unilateral block application in chronic
migraine patients and whether there were differences in their effectiveness retrospectively . -
pubmed
In chronic
migraine patients undergoing Greater occipital nerve ( GON ) block , mean number of days with
pain per month before and after block , mean duration of
pain in attacks ( in hours ) , and mean Visual Analog Scale ( VAS ) in attack and
pain severity were recorded from files . -
pubmed
METHODS :
Sprague - Dawley rats were used to establish
AP model by intraperitoneal injection of 20 %
L - arginine ( 4 g / kg ) twice with an interval of 1 hour . -
pubmed
Thrombophilia , elevated estrogenic states , and
infections are the most common risk factors in
patients who develop
CVT . -
pubmed
CASE : A 69 - year - old
man with a right - sided
odontogenic infection presented with
fever ,
headache ,
opthalmoplegia , and
periorbital swelling . -
pubmed
Unfractionated or low molecular weight heparin may be safely used in
CVT patients . -
pubmed
MATERIALS AND METHODS : This retrospective study included 249 consecutive
patients who underwent evaluation for normal pressure
hydrocephalus . -
pubmed
pestis ) has caused an alarming number of
deaths throughout recorded
human history , and novel prophylactics and therapeutics are necessary given its potential as a bioweapon . -
pubmed
pestis 141
infection when administered prophylactically to
Balb / c mice ( 100 mug intravenously ) . -
pubmed
Enhanced antitumor activity of surface - modified
iron oxide nanoparticles and an
alpha - tocopherol derivative in a
rat model of
mammary gland carcinosarcoma . -
pubmed
Wistar rats with
Walker-256 carcinosarcoma ( a model of
mammary gland carcinosarcoma ) received
Toc-6 - Ac , magnetic nanoparticles , or their combination per os , and the antitumor activity of each treatment was determined in vivo . -
pubmed
To investigate the comparative effects on the
body weight , organ weight and lipid profile , the crude oil of
Silybum marianum , edible
sunflower oil and vegetable
ghee were given to three groups of
rabbits under study . -
pubmed
METHODS : The effects of
ADM _ 12 on
nitroglycerin - induced
hyperalgesia at the trigeminal level were investigated in male
rats using the quantification of nocifensive behavior in the orofacial
formalin test . -
pubmed
RESULTS : In
rats bearing
nitroglycerin - induced
hyperalgesia ,
ADM_12 showed an anti -
hyperalgesic effect in the second phase of the orofacial
formalin test . -
pubmed
Patient - specific
seizure detection in long - term EEG using signal - derived empirical mode decomposition ( EMD)-based dictionary approach . -
pubmed
OBJECTIVE : The objective of the work described in this paper is the development of a computationally efficient methodology for
patient - specific automatic
seizure detection in long - term multi - channel EEG recordings . -
pubmed
The renewed interest to this class of evoked potentials is due to unexplained differences in the results of cochlear implantation in the
patients with the similar audiological data , etiology , age and the history of
deafness as well as cochlear implant surgery in
children of first years of life and the extended possibilities for speech processor programming . -
pubmed
It is concluded that the longer duration of
deafness and later age at implantation result in immature morphology and delayed peak latencies and that
patients with shorter latencies and higher amplitudes have better speech perception . -
pubmed
METHODS : Pre - planned analysis of the prospective multinational TAVeM database , performed on 2960
patients receiving mechanical ventilation for & gt;48 h , including 689
patients with VA -
LRTI . -
pubmed
RESULTS : Four hundred and four
patients ( mean age 63 years , 298
men , ICU mortality 40 % ) were studied , 207 with
VAT and 197 with
VAP . -
pubmed
We confirmed increases in
insulin resistance ,
glucose tolerance ,
peripheral inflammation and dysarteriotony in PM2.5 - induced
mice . -
pubmed
BACKGROUND : Easily accessible biomarkers are needed for the early identification of
individuals at risk of developing
Alzheimer ' s disease (
AD ) in large population screening strategies . -
pubmed
The mass production and consumption of medication for the treatment of
infectious diseases in
human and animals have led to the ubiquity of antibiotics in the environment . -
pubmed
We studied the single and joint effects of microplastics ( 1 - mum and 10 - mum
polystyrene particles , PS ) and
roxithromycin (
ROX ) on
Daphnia magna through the
acute and sublethal toxicity tests . -
pubmed
Blood - brain barrier dysfunction in
canine epileptic seizures detected by dynamic contrast - enhanced magnetic resonance imaging . -
pubmed
OBJECTIVE :
Dogs with spontaneous or acquired
epilepsy exhibit resemblance in etiology and disease course to
humans , potentially offering a translational model of the
human disease . -
pubmed
To test the hypothesis that
BBBD can be detected in
dogs with naturally occurring
seizures , we developed a linear dynamic contrast - enhanced magnetic resonance imaging ( DCE - MRI ) analysis algorithm that was validated in clinical cases of seizing
dogs and experimental
epileptic rats . -
pubmed
METHODS : Forty - six
dogs with naturally occurring
seizures of different etiologies and 12 induced
epilepsy rats were imaged using DCE - MRI . -
pubmed
RESULTS : We found
BBBD in 37 % of
dogs with
seizures . -
pubmed
A significant difference was found between
epileptic and control
rats when BBBD scores were calculated for the piriform cortex at 48 hours and 1 month after
status epilepticus . -
pubmed
Mean BBBD score of the piriform lobe in
idiopathic epilepsy (
IE )
dogs was significantly higher compared to control . -
pubmed
SIGNIFICANCE : Detection of
BBBD in
dogs with naturally occurring
epilepsy provides the ground for future studies for evaluation of novel treatment targeting the disrupted BBB . -
pubmed
Under the optimal conditions , the
yeast strain could yield 73.25 + - 2.3 g / L of EPS within 5 days at a flask level . -
pubmed
The mutant DAG27 was more sensitive to radiation of UV light , high
NaCl concentration , heat treatment , strong oxidation of
H2O2 and desiccation than its wild type
strain 13 - 2 , suggesting that the produced pullulan could play an important role in resistance of the
yeast cells to various stresses . -
pubmed
This was the first time to show that the
yeast strain obtained from the desert could produce such high level pullulan and the produced pullulan had an obviously protective effect on its producer . -
pubmed
Methods : We present three
children of a family with progressive
weakness , mild
sensory loss , and
absent tendon reflexes . -
pubmed
Electrodiagnostic analyses displayed an axonal type of
neuropathy in affected
patients . -
pubmed
Results : All affected
individuals manifested identical clinical symptoms of motor and sensory impairments within the first three years of life , and nerve conduction study indicated the
axonal degeneration . -
pubmed
In this hemodynamic rounds discussion , we evaluated a
patient with
MS and PHT prior to the decision for mitral valvuloplasty . -
pubmed
KEY POINTS : Symptoms in
patients with
mitral stenosis and
pulmonary hypertension can not always be attributed to one pathology . -
pubmed
Luteolin reduces adipose tissue macrophage
inflammation and
insulin resistance in postmenopausal
obese mice . -
pubmed
Previously , we showed that loss of ovarian function in
mice fed high - fat diet exacerbated
insulin resistance and
adipose tissue inflammation . -
pubmed
In the current study , we tested whether consumption of
luteolin , an anti - inflammatory
flavonoid , could mitigate
adipose tissue inflammation and
insulin resistance in
obese ovariectomized
mice . -
pubmed
Results showed no difference in
body weight or fat mass between
mice fed HFD+L and those fed HFD . -
pubmed
Human trichinellosis is a disease caused by nematode worms of the genus Trichinella . -
pubmed
In Italy , as well as in most other European countries , notification of
Trichinella infections in
humans is mandatory ; however , no information is available on the number of cases occurring annually . -
pubmed
INTRODUCTION : Ablation remains a modality of choice in select
patients with
Atrial fibrillation (
AF ) . -
pubmed
Studies comparing the use of surgical or catheter ablation in
patients with
AF were included . -
pubmed
RESULTS : Eight studies ( 744
patients ) reported a statistically significant difference in
Arrhythmia recurrence rate between surgical and catheter - based ablation . -
pubmed
This review surveys the research of power - based models of
fatigue and recovery within the area of
human performance . -
pubmed
Purpose : The aim of this study was to compare the metabolic load between adaptive support ventilation ( ASV ) and pressure support ventilation ( PSV ) modes in
critically ill patients . -
pubmed
Methods : Sequential 20 min ventilation by PSV followed by 20 min ASV in
critically ill patients was assessed . -
pubmed
Results : Twenty - four
patients with
critical illness participated in the study . -
pubmed
Birth weight and subsequent
weight gain is of critical importance in the survival and performance of piglets on a commercial
swine farm setting . -
pubmed
Thus , providing a basis for the development of strategies aimed at improving
weight gain in
pigs . -
pubmed
Bioresorbable scaffolds versus permanent
sirolimus - eluting stents in
patients with
ST - Segment Elevation Myocardial Infarction : vascular healing outcomes from the MAGSTEMI trial . -
pubmed
We report a 21 - year - old
woman who presented with dorsoulnar wrist
pain during palmar wrist flexion and soft tissue mass at the site of
pain . -
pubmed
Conservative treatment for 3 months failed to improve the
patient 's
pain levels . -
pubmed
METHOD :
Patients with
HCC undergoing rTACE at six Australian tertiary centers from 2009 to 2014 were included . -
pubmed
RESULTS : Total of 292 consecutive
patients underwent rTACE with mainly Child Pugh A
cirrhosis ( 61 % ) and BCLC stage A ( 57 % ) disease . -
pubmed
Non - invasive brain stimulation in
Stroke patients ( NIBS ): A prospective randomized open blinded end - point ( PROBE ) feasibility trial using transcranial direct current stimulation ( tDCS ) in
post - stroke hemispatial neglect . -
pubmed
Up to 80 % of
people who experience a
right - hemisphere stroke suffer from
hemispatial neglect . -
pubmed
We carried out a clinical feasibility trial of transcranial direct current stimulation ( tDCS ) and a behavioural rehabilitation programme , alone or in combination , in
patients with
neglect . -
pubmed
RESULTS : Twelve prospective studies were assessed , including 536
patients with
CRCLMs ( n = 1335 ) . -
pubmed
We present a case of an isolated acute dorsal
dislocation of the distal radioulnar joint in a 25 - year - old
man . -
pubmed
However , the loop metavaccine with Freund 's complete adjuvant ( CFA ) reduced
cancer progression and
metastasis while that with alum , to our surprise , were adversely affected in 3
tumor bearing
mouse models . -
pubmed
Based on these observations , we concluded that multiple immune parameters are to be considered when applying a vaccine strategy to
cancer patients . -
pubmed
OBJECTIVES : To evaluate and compare the efficacy of National Early Warning Score , National Early Warning Score 2 , Rapid Emergency Medicine Score ,
Confusion , Respiratory rate , Blood pressure , Age 65 score , and quick
Sepsis - related Organ Failure Assessment on predicting in - hospital
death in
patients with
coronavirus disease 2019 . -
pubmed
SETTING : Single center , West Campus of Wuhan Union hospital - a temporary center to manage
critically ill patients with
coronavirus disease 2019 . -
pubmed
Disrupted Regional Homogeneity in Drug - Naive
Patients With
Bipolar Disorder . -
pubmed
Objective : Studies on alterations in the regional neural activity in the brain of
patients with
bipolar disorder (
BD ) have provided conflicting results because of different medications used and study designs . -
pubmed
This study aimed to further explore regional neural activities in unmedicated
patients with
BD and their association with
BMD . -
pubmed
Methods : In this study , 40
patients with
BD and 42 healthy controls were scanned through resting - state functional magnetic resonance imaging ( fMRI ) . -
pubmed
Conclusion : This study further confirms the abnormal brain activities in extensive regions , and these brain regions are primarily located in the fronto - temporal - occipital circuit and the cerebellum vermis of
patients with
BD . -
pubmed
Effect of
androgen deprivation therapy on cardiovascular function in Chinese
patients with advanced
prostate cancer : a prospective cohort study . -
pubmed
Androgen deprivation therapy ( ADT ) is the standard treatment for advanced
prostate cancer , but its effect on cardiovascular and metabolic function in Asian
patients is still inconclusive . -
pubmed
We prospectively assess the effects of ADT on 36
patients with advanced
prostate cancer , with reference to another 24
prostate cancer patients not requiring ADT , for 2 years . -
pubmed
ADT -
patients were 4.9 times more likely to have
metabolic syndrome at 24 months . -
pubmed
Commentary on "
Urtica dioica in comparison with placebo and acupuncture : A new possibility for
menopausal hot flashes : A randomized clinical trial " by Rahele Kargozar et al . -
pubmed
Adult
patients ( at least 18 years of age ) undergoing open , elective , ventral
hernia repairs with mesh placed in the retromuscular position were enrolled . -
pubmed
Secondary outcomes included total inpatient
opioid use ,
pain scores determined using a 100 mm visual analog scale , length of hospital stay , and
patient - reported quality of life . -
pubmed
Similarly , there were no differences in total inpatient opioid use ,
pain scores , length of stay , and
patient - reported quality of life . -
pubmed
RESULTS : We experienced differences in the usability of piggyBac - based germline transformation in different
strains of
D. - pubmed
RESULTS : We assessed 156
patients with
nonsyndromic lower extremity VM ; 71 ( 46 % ) were focal , and 85 ( 54 % ) were diffuse type
VM , and 97 ( 62 % ) were IA -
VM . -
pubmed
The YM / PU column implanted in the back subcutis or vagina of the
mouse rapidly recovered to its original state within 60 s under a very low NIR laser ( 808 nm , 0.5 W / cm2 ) intensity , which is much lower than the general laser intensity for photothermal
cancer therapy ( 1 - 2 W / cm2 ) . -
pubmed
METHODS : Data regarding professions , wet work exposure , activities performed during working hours , self - reported
eczema were collected from 230 nurse
students , divided in two study groups : the intervention and the control group ( CG ) . -
pubmed
The histology of the gastric mucosa of two
subjects with severe lesions showed spotty to moderate chronic superficial
gastritis , whereas the overall histological appearance of the mucosa was normal in subjects with slight or moderate lesions after drug administration . -
pubmed
Sudden sensorineural hearing loss : electrocochleographic findings in 70
patients . -
pubmed
The results of transtympanic ECochG in 70
patients with
sudden sensorineural deafness are presented . -
pubmed
ECochG gave a definite localization of the
deafness in 22 out of 23
patients in whom conventional methods of audiometry had produced equivocal results and was also found to be extremely valuable in 17
patients with " dead " ears . -
pubmed
[ Endoscopic control of
patients subjected to vagotomy and drainage for
duodenal ulcer . -
pubmed
The usefulness of endoscopic examination of
patients subjected to vagotomy and drainage for
duodenal ulcer is stressed , since it permits
recurrences and ineffective treatment to be detected , along with the control of other parameters , such as the appearance of the mucosa , the performance of gastric drainage , the features of peristalsis and gastric tone , and the performance of the cardial sphincter . -
pubmed
Acoustic neurinoma in a
child : a case study . -
pubmed
This case study reports the audiological and surgical findings for a nine - year - old
boy with an
acoustic neurinoma . -
pubmed
The
patient had a 5 cm acoustic
neurinoma compressing and adherent to the brain stem . -
pubmed
[ Pathomorphology of
human hepatic echinococcosis and
alveococcosis ] . -
pubmed
This apparent
morphine - induced
atrophy of these important accessory sex organs was not due to a change in the nutritional status of the
animals but rather appeared to be associated with a pronounced ( 87 percent ) reduction in the serum
testosterone levels of
morphine - treated
rats when compared to control levels . -
pubmed
Sera from
patients with
tuberculoid leprosy and control sera gave very weak binding . -
pubmed
leprae was obtained by immunochemistry of
lepromatous leprosy lesions with a monospecific antibody raised against
M. - pubmed
This probe does not hybridize to the DNA of non - toxigenic
strains of
C. - pubmed
A preliminary study of direct probing of faecal specimens indicates a potential for the use of this DNA probe in the clinical laboratory for the rapid identification of toxigenic
strains of
C. - pubmed
Fourteen adult
patients undergoing open heart surgery under induced
hypothermia had median nerve , short - latency somatosensory evoked potentials ( SSEPs ) recorded during cooling ( from 36 degrees C to 19 degrees C ) and subsequent rewarming . -
pubmed
Between 1983 and 1990 , 59
patients with
malignant melanoma were retrospectively reviewed to assess the safety , efficacy and the maximal tolerated dose of
cisplatin used in hyperthermic isolated limb perfusion . -
pubmed
In 75 % of
patients in group 3 a
traffic accident was the lesion mechanism . -
pubmed
Selective
cytotoxicity against
human tumor cells by an anti -
gastric cancer monoclonal antibody -
mitomycin C conjugate . -
pubmed
The conjugate showed a highly selective
cytotoxicity upon
human gastric cancer cells
KATO - III . -
pubmed
Supersensitivity of isolated coronary artery to
ergonovine in a
patient with
variant angina . -
pubmed
Na(+)-dependent , active
nucleoside transport in
mouse spleen lymphocytes ,
leukemia cells , fibroblasts and macrophages , but not in equivalent
human or
pig cells ;
dipyridamole enhances
nucleoside salvage by cells with both active and facilitated transport . -
pubmed
Formycin B influx studies have shown that
P388 and
L1210 mouse leukemia cells ,
mouse L929 cells ,
mouse RAW 309 Cr.1 cells ,
LK35.2 mouse B - cell hybridoma cells and cultured
mouse peritoneal macrophages express both
Na(+)-dependent , active and nonconcentrative , facilitated
nucleoside transport systems . -
pubmed
Finally ,
cyst or follicle - like structures lined by immunostained cells with basal processes could be observed in the anterior lobe of the
rat , but not in that of the
rabbit or the
cat . -
pubmed
In 37 test persons with healthy vessels and 103
patients with
arterial obstructive disease the clinical findings of the
pulse palpation were related to the results of the systolic Doppler pressure measurement in the region of the posterior tibial artery . -
pubmed
Effect of
nifedipine on left ventricular function during exercise in
patients with stable
effort angina . -
pubmed
To evaluate whether the effect of
nifedipine on left ventricular function relates to the severity of
coronary artery disease (
CAD ) or not , supine graded ergometer exercise testing was performed before and after sublingual administration of 10 mg
nifedipine in 24
patients with stable
effort angina . -
pubmed
After
nifedipine , left ventricular function ( % EF ) was improved in all 6
patients with mild
CAD , but was worsened in all 9
patients with severe
CAD . -
pubmed
Maximal ST segment depression during exercise was improved in 5 of 6
patients with mild
CAD , while improvement was induced in 5 of 9
patients with moderate
CAD and in 3 of 9
patients with severe
CAD . -
pubmed
At the Radiotherapeutic Department of the Faculty of Medicine in Istanbul , 35 masculine
patients with
microcellular bronchial carcinoma , limited disease , were treated for two years , i.e. -
pubmed
Nine out of these
patients are
tumor - free after at least 46 months , i.e. -
pubmed
Four
patients with
chlorpromazine - induced
pigmentation showed resolution of the condition on replacing
chlorpromazine with
haloperidol . -
pubmed
Risks to postoperative
patients include an increase in metabolic rate of up to 400 % ,
hypoxemia ,
wound dehiscence ,
dental damage , and disruption of delicate surgical repairs . -
pubmed
Signals from each muscle were compared to those of pathologic clonus induced by plantar flexion in unanesthetized
patients with
spinal cord transections and to those of cold - induced
shivering in normal , unanesthetized
subjects . -
pubmed
Two distinct EMG patterns were identified : 1 ) regular , bursting signals of 5 - 7 Hz similar to those produced by pathologic clonus in
patients with
spinal cord transections ; and 2 ) tonic , irregular signals of 5 - 15 Hz which had poorly defined bursts that did not demonstrate the synchronous 4 - 8 - cycle / min waxing and waning pattern typical of normal shivering . -
pubmed
During the later part of recovery when
isoflurane concentrations were less than or equal to 0.1 % ,
hypothermic patients frequently demonstrated no clinical or EMG evidence of muscular activity. -
pubmed
One hundred and sixty - five
patients with localized
cancer of the lower lip were excised and reconstructed over a 25 - year period using Bengt Johanson 's step technique . -
pubmed
Nine local
recurrences appeared in 5
patients , none of whom died of
lip cancer . -
pubmed
Eight
patients later developed regional
metastases and 3 of these
patients died of
lip cancer . -
pubmed
The I score was used to divide
patients into groups at different risk of
recurrence : low , moderate and high ( 97.5 % , 45 % and 22.5 % of
recurrence - free
patients at 3 years respectively ) . -
pubmed
Rapid fluid replacement for severe
hypovolemia --
human subject trials . -
pubmed
Successful resuscitation of a
hypovolemic patient often requires rapid intravenous administration of massive amounts of fluid . -
pubmed
We report the system 's use in five
patients with severe
hypovolemia following
trauma . -
pubmed
The investigations have been made in
children aged 1.5 - 4 years , immunized with live
measles vaccine prepared from
strain l-16 . -
pubmed
Effect of functional rehabilitation on blood lipid values in a group of
patients with
neuromotor lesions ] . -
pubmed
[ Etiology of
intestinal disorders in young
children with acute
respiratory diseases ] . -
pubmed
Immunoelectrophoretic characteristics of plasma from
rats with adjuvant
arthritis . -
pubmed
Binding to
R 1881 (
methyltrienolone ) of proteins from
human benign
prostatic hypertrophy . -
pubmed
Cytosol of
human benign
prostatic hypertrophy bound to R 1881 in a high affinity manner . -
pubmed
Four
patients developed abnormal
involuntary movements of a limb after
injury . -
pubmed
Sympathetic block in three
patients did not relieve the
abnormal movements . -
pubmed
[ Nomenclature for
strains of
poliovirus ] . -
pubmed
Staphylocidal defect of polymorphonuclear leukocytes in a
patient with
leprechaunism . -
pubmed
Cerebrospinal fluid flow abnormalities in
patients with
neoplastic meningitis . -
pubmed
Cerebrospinal fluid flow dynamics were evaluated by
111Indium - diethylenetriamine pentaacetic acid (
111In - DTPA ) ventriculography in 27
patients with
neoplastic meningitis . -
pubmed
These data indicate that cerebrospinal fluid flow abnormalities are common in
patients with
neoplastic meningitis and that
111In - DTPA cerebrospinal fluid flow imaging is useful in characterizing these abnormalities . -
pubmed
This technique provides insight into the distribution of intraventricularly administered chemotherapy and may provide explanations for treatment failure and drug - induced
neurotoxicity in
patients with
neoplastic meningitis . -
pubmed
160
mice of the BALB / C
strain of both sexes , aged 3 months , were divided into four equal groups out of which two were regularly irritated by a combination of an optical signal and electrical
stroke . -
pubmed
Thus , the method is considered to be quite beneficial in taking care of advanced
cancer patients . -
pubmed
Idiopathic osteonecrosis of the femoral capital epiphysis in
children . -
pubmed
Two
patients with minimal
amyloid deposition in association with
nephrotic syndrome are reported . -
pubmed
In this study , we used a
rat model of
middle cerebral artery occlusion (
MCAO ) of permanent focal
ischemia . -
pubmed
Normothermic
animals ( n = 13 ) had a baseline
glutamate concentration of 9.23 + /- 2.5 mumol / ml ( mean + /- standard error of the mean ) before
MCAO . -
pubmed
Clinical studies in
Alzheimer patients with positron emission tomography . -
pubmed
Brain imaging techniques will in the future play an important role in the assessment of
patients with
neurogenerative disorders such as
Alzheimer ' s disease (
AD ) . -
pubmed
Longitudinal studies will here be important and especially in
individuals with a family history of
AD . -
pubmed
A reduced uptake and binding of
[ 11C ] nicotine in the temporal and frontal cortices have been measured in
AD patients by PET . -
pubmed
PET studies indicate that long - term
tacrine treatment in
AD patients with mild
dementia improves functional activities in brain . -
pubmed
COM stones were found in older patients than COD stones ( p & lt ; 0.05 ) ; 45.2 + /- 12.8 and 39.9 + /- 11.2 years old for 51 COM stone
patients and 54 COD stone patients . -
pubmed
Fifty - three
patients were followed at yearly intervals without any prophylactic treatment for stone
recurrence . -
pubmed
Identification in the sera from
patients with advanced
cancer of a factor which stimulates gene expression from
human immunodeficiency virus type 1 . -
pubmed
These results suggest that the onset of cellular and humoral immune responses after immunization may be important as a biological control of
myiasis and contribute to better understanding of the immune defense mechanism of the host against
D. - pubmed
Exhaled
nitric oxide may be a useful marker of
inflammation and has recently been shown to be increased in
patients with
asthma . -
pubmed
OBJECTIVE : The purpose of this study was to determine whether exhaled levels of
nitric oxide are increased with nasal breathing in
patients with
seasonal allergic rhinitis compared with nonatopic individuals and whether there is an increase with oral breathing consistent with lower
respiratory inflammation in the absence of clinical
asthma . -
pubmed
METHODS :
Nitric oxide levels in exhaled air were measured by chemiluminescence in 18 nonatopic
volunteers and 32
patients with
seasonal rhinitis . -
pubmed
Levels of exhaled
nitric oxide were significantly higher for all measurements in
patients with
seasonal rhinitis , with levels without breath - holding of 35.4 + /- 11.3 ppb ( p less than 0.001 ) in nasally exhaled air and 16.3 + /- 5.9 ppb ( p less than 0.001 ) in orally exhaled air . -
pubmed
CONCLUSIONS : The results indicate that exhaled
nitric oxide may be a useful marker for
nasal inflammation in
patients with
seasonal rhinitis and suggest that generalized
airway inflammation may be present , even without clinical
asthma , in such patients . -
pubmed
Thirty
parturients undergoing elective cesarean section under spinal anesthesia were randomly allocated to receive postoperative
pain management with ( S - E group , n = 15 ) or without epidural
bupivacaine ( S group , n = 15 ) . -
pubmed
Our sample included an initial group of 40
patients who had
growth delay / constitutional delay of growth and puberty ( n = 10 ) ,
growth hormone insufficiency / deficiency ( n = 15 ) ,
low birth weight /
Silver - Russell syndrome ( n = 9 ) ,
precocious puberty ( n = 6 ) , as well as 20
patients with various
skeletal dysplasias (
multiple epiphyseal dysplasia n = 7 ,
pseudoachondroplasia n = 7 ,
acrodysostosis n = 5 ,
achondroplasia n = 1 ) , 7
girls with
Turner syndrome , and 10
boys with
nephrotic syndrome on chronic
corticosteroid treatment . -
pubmed
Depression of A and C fibre - evoked segmental reflexes by
morphine and
clonidine in the in vitro spinal cord of the neonatal
rat . -
pubmed
Under exercise conditions where untrained
animals demonstrate substantial reductions in blood
glucose , training enhanced
hypoglycemic resistance has been shown to result entirely from enhanced
glucose production via gluconeogenesis . -
pubmed
It is concluded that the improved hepatic gluconeogenic capacity of endurance trained
individuals , at least in
rats , is critical to their demonstrated resistance to exercise - induced
hypoglycemia . -
pubmed
The effects of
sevoflurane on recovery of brain energy metabolism after
cerebral ischemia in the
rat : a comparison with
isoflurane and
halothane . -
pubmed
Conversely , topical
corticosteroids may suppress the development of local cutaneous
irritation that occurs in
patients treated with
calcipotriene ointment . -
pubmed
OBJECTIVES : We report the occurrence of cardiac events during long - term follow - up in
patients with
hypertrophic cardiomyopathy (
HCM ) after cardioverter - defibrillator implantation . -
pubmed
BACKGROUND : The identification of
patients at high risk for
sudden death and the prevention of
recurrence of
sudden death in
HCM represents a difficult problem . -
pubmed
METHODS : We retrospectively analyzed the occurrence of cardiac events during follow - up of 13
patients with
HCM who received an implantable cardioverter - defibrillator ( ICD ) because of aborted
sudden death ( n = 10 ) or sustained
ventricular tachycardia ( n = 3 ) ( group I ) . -
pubmed
RESULTS : After a mean ( + /-SD ) follow - up period of 26+/-18 months , 2 of 13
patients in group I received appropriate
shocks . -
pubmed
We observed a low incidence of recurrence of
ventricular tachycardia /
fibrillation during follow - up in
patients with
HCM . -
pubmed
CONCLUSIONS : Our data suggest that
ventricular tachyarrhythmias may not always be the primary mechanism of
syncope and
sudden death in
patients with
HCM . -
pubmed
The ICD seems to have a less important impact on prognosis in
patients with
HCM than in patients with other etiologies of aborted
sudden death . -
pubmed
The overall prevalence of mixed
infections , assessed by PCR , was 37.1 % ; the majority ( 72.7 % ) involved
T. - pubmed
Prediction of axillary lymph node involvement of
women with invasive
breast carcinoma : a multivariate analysis . -
pubmed
METHODS : We examined 308
patients presenting with suspected but not previously known
CAD who underwent selective coronary angiography . -
pubmed
CONCLUSIONS : Coronary
calcium predicts the angiographic extent of
CAD in symptomatic
patients and provides independent and incremental information to the more conventional clinical parameters derived from SPECT or risk assessment . -
pubmed
Because
cytomegalovirus (
CMV ) is an important
opportunistic infection after liver transplant , we conducted a prospective study to see if the same applied to
human herpesviruses (
HHV)-6 and -7 . -
pubmed
Active
infection with
CMV was detected in 28/60 ( 47 % ) ,
HHV-6 in 19/60 ( 32 % ) , and
HHV-7 in 29/60 ( 48 % ) of patients . -
pubmed
The median peak virus load for
CMV was significantly greater than that for
HHV-6 or
HHV-7 . -
pubmed
Detailed clinicopathological analyses for the whole population showed that
CMV and
HHV-6 were each significantly associated with biopsy - proven graft rejection . -
pubmed
Individual case histories suggested that
HHV-6 and
HHV-7 may be the cause of some episodes of
hepatitis and
pyrexia . -
pubmed
It is concluded that
HHV-6 is a previously unrecognized contributor to the morbidity of liver transplantation , that
HHV-7 may also be important and that both viruses should be included in the differential diagnosis of
graft dysfunction . -
pubmed
Following comprehensive literature search and communication with other researchers , 34 items about viral load testing ,
HIV therapies and concern about
HIV infection were generated . -
pubmed
The knockout study also suggested that the brain of
PIMT - deficient mice manifested neurodegenerative changes concomitant with accumulation of
L - isoaspartate . -
pubmed
We discuss the pathological implications of protein isomerization in the neurodegeneration found in model
mice and
AD . -
pubmed
First case was a 27 - year - old
man with
cerebral palsy . -
pubmed
Second case was a 55 - year - old
man with
lung cancer , terminal stage . -
pubmed
Third case was a 60 - year - old
man with
amyotrophic lateral sclepsis . -
pubmed
The aim of this investigation was to study
retinol , which is known to decrease in hepatic stellate cells during fibrogenesis , and
dolichol , which influences membrane fluidity and decreases in
liver injury , in freshly isolated liver parenchymal and nonparenchymal cells after intoxication of
rats with
CCl4 combined with the ionophore
monensin for 3 , 5 and 7 weeks . -
pubmed
PURPOSE : To determine whether the blastocyst
zona shedding process within the
murine uterine cornus in vivo is due to a global lytic process caused by uterine proteolytic enzyme , or is triggered by the blastocyst hatching process as observed in vitro . -
pubmed
Dynamics of
porcine circovirus type 2 infection in a herd of
pigs with postweaning
multisystemic wasting syndrome . -
pubmed
OBJECTIVE : To determine the pattern of
infection for porcine circovirus type 2 (
PCV2 ) in a herd of
pigs with postweaning
multisystemic wasting syndrome (
PMWS ) . -
pubmed
RESULTS : The
PMWS started when
pigs were 8 weeks old , with a prevalence of 30 % in 8- to 10 - week - old
pigs . -
pubmed
Microscopic lesions consistent with
PMWS were observed , and
PCV2 nucleic acid was detected ( 50 of 68
pigs ) . -
pubmed
CONCLUSIONS AND CLINICAL RELEVANCE :
Infection with PCV2 coincided with severe clinical signs ; however , infected 28 - week - old
pigs did not have evidence of disease . -
pubmed
A long duration of
PCV2 viremia was apparent in a high percentage of infected
pigs , which may affect transmission and persistence of the virus in a herd . -
pubmed
BACKGROUND : The objective of this study was to comprehensively characterize the clinical and biologic features of
adenoid cystic carcinoma (
ACC ) and to assess the implications for management in a large cohort of
patients . -
pubmed
METHODS : From a database of 50,000
patients , 28 were identified with
ACC for which clinical follow - up and biologic information was available . -
pubmed
One
patient had macroscopic metastatic
disease at diagnosis . -
pubmed
METHODS : A 53 - year - old
male with
chronic myeloid leukemia presented with prolonged involuntary painful erection of 12 hours ' duration . -
pubmed
BK polyomavirus
interstitial nephritis in a renal transplant
patient with no previous acute rejection episodes . -
pubmed
This case shows that even in the absence of vigorous anti - rejection therapy an immunosuppressive regimen based on
tacrolimus and
MMF may involve the risk of
BK polyoma virus- associated
interstitial nephritis . -
pubmed
A total of 332
patients treated for chronic
HCV infection were evaluated . -
pubmed
Using multivariate logistic regression analysis , the impact of the rate of
fibrosis progression ( defined as the stage of
liver fibrosis according to the Metavir system / duration of
infection ) on the rate of SVR ( negative
HCV RNA at least 6 months following the end of treatment ) , was determined . -
pubmed
The median rate of
fibrosis progression was 0.083 ( range 0 - 2 ) Metavir units / year ; 158
patients ( 48 % ) had F2 - F4
fibrosis . -
pubmed
In this study , a total of 225
methicillin resistant
Staphylococcus aureus strains isolated from various clinical specimens ( 114
wounds , 27 blood , 16 of each catheter and sputum , 14 throat swabs , 10 tracheal aspirates , 7 of each urine and drain materials , 6 pleural fluids , 5 graft materials , 2 cerebrospinal fluids , 1 ascitis fluid ) of hospitalized
patients , were tested in - vitro for their susceptibilities to
fusidic acid and
trimethoprim - sulfamethoxazole (
TMP -
SMX ) by disk diffusion method . -
pubmed
Molecular analysis of
Staphylococcus aureus blood isolates shows lack of polyclonal
bacteremia . -
pubmed
Molecular analysis of the first blood culture from 41 patients with
Staphylococcus aureus bacteremia and 20
bacteremia - associated catheter tip isolates revealed indistinguishable blood colonies in 39 patients ( 95.1 % ) and two related variants in two patients ( 4.9 % ) . -
pubmed
Good surgical technique and local anti -
hemorrhagic treatment are essential in oral surgery , particularly in
patients taking anti - platelets or oral anticoagulants . -
pubmed
Adrenal cortical insufficiency in the
rhesus monkey . -
pubmed
REPORT ON FERTILITY AFTER
VIRILIZATION WITH
ANDROGENS IN A
MAN WITH MINUTE TESTICLES AND
EUNUCHOIDISM . -
pubmed
All
rabbits were bled for evaluation of hematologic parameters for the stress
triad (
neutrophilia ,
lymphopenia , and
eosinopenia ) and weighed weekly . -
pubmed
No significant differences were found between study and control
rabbits when
body weights , food consumption , and hematologic parameters were analyzed . -
pubmed
Some
hypotensive preterm
infants have low
cortisol levels , and
corticosteroids are being used increasingly to prevent or treat
hypotension in these babies . -
pubmed
HORTON ' S SYNDROME , A
VASCULAR DISEASE : The destruction of the arterial wall at the acute stage of the disease appears responsible , sometimes later on , for aneurismal dilatations observed on the aorta of certain
patients . -
pubmed
A viral role in the development of
lymphomas and of
Kaposi sarcoma in
HIV - infected individuals would account for neoplastic aggressiveness and for a particular predilection for primary
CNS lymphoma . -
pubmed
Such a role perhaps implicates viral integration within the genome of host cells that are actively proliferating or else infected by multiple viral pathogens such as
EBV ,
HIV-1 ,
CMV , and
Herpes virus . -
pubmed
UNLABELLED :
Hepatocellular carcinoma (
HCC ) is an important type of
cancer etiologically related to some viruses , chemical carcinogens and other host or environmental factors associated to
chronic liver injury in
humans . -
pubmed
Women in group 1 had nine
urinary tract injuries ( 3.28 % ) , including eight cases of intraoperative
bladder injury ( 2.91 % ) and one
vesicovaginal fistula ( 0.36 % ) , but no
ureteral injury . -
pubmed
METHODS : We observed the survival time to
hypoxia and heat survival rate of the
mice treated with different doses of PHAS and
vitamin E. -
pubmed
Whereas first - episode
patients showed significantly diminished
flush response as compared to controls , comparable differences were not found between multi - episode
patients and controls . -
pubmed
METHODS : Both studies were 8 - week , double - blind , comparison studies of
men and
women with DSM III - R major
depression . -
pubmed
This study aimed to : classify a cohort of children and adolescents with
myotonic dystrophy (
dystrophia myotonica :
DM ) into congenital and childhood onset forms ; estimate CTG expansion size ; and quantify muscle strength ,
contractures , and motor function in
children with
DM and compare results with those of controls . -
pubmed
Participants were : 42
children with
DM ( 18 females , 24
males ; mean age 8y 9mo [ SD 4y 7mo ] , range 10mo to 17y ) and 42 age- and sex - matched , healthy controls . -
pubmed
Children with
DM were divided into three groups : severe congenital ( n=13 ) , mild congenital ( n=15 ) , and childhood ( n=14 ) . -
pubmed
Children with childhood
DM were significantly weaker than controls ( wrist and ankle dorsiflexors [ p=0.0044 , p=0.0044 respectively ] ; hip abductors and flexors [ p=0.0464 , p=0.0217 ] ; and knee flexors and extensors : [ p=0.0382 , p=0.0033 ] ) . -
pubmed
Children with mild
congenital DM were significantly weaker than controls in all assessed muscle groups . -
pubmed
Children with severe
congenital DM had the lowest motor function , with correlation between motor function and size of CTG repeat ( p=-0.743 ) . -
pubmed
Prevalence of
atherosclerosis of the coronary and extracranial cerebral arteries in
patients undergoing aortic valve replacement for
calcified stenosis . -
pubmed
METHODS : In 282 consecutive
patients with severe
calcific stenosis of a tricuspid aortic valve scheduled for aortic valve replacement , the prevalence of atherosclerotic changes of the coronary and extracranial cerebral arteries were assessed using coronary angiography and Doppler sonography , respectively . -
pubmed
Coronary or
extracranial cerebral artery stenosis was present in 59 % and 16 % of
patients , respectively , while 91 % of the study population and all
patients aged & gt ; 80 years showed
atherosclerosis of the coronary and/or extracranial cerebral arteries . -
pubmed
CONCLUSION : The data obtained indicated a very high prevalence of atherosclerotic changes in
patients with
calcific AS , suggesting pathogenetic similarities of both disorders . -
pubmed
Routine screening of the extracranial cerebral arteries is warranted in all
patients with
calcific AS and scheduled for valve replacement . -
pubmed
The potential for enhancement of
mouse melanoma metastasis by diagnostic and high - amplitude ultrasound . -
pubmed
The
melanoma cell line
B16 - D5 , which is metastatic specifically to lung , was cultured and implanted on a hind leg of female
C57 / bl6 mice . -
pubmed
We analyzed event - related potentials ( ERPs ) and behavioral measurements during a recognition memory task in 15 normal elderly
subjects and 15
patients with
Parkinson ' s disease (
PD ) . -
pubmed
Long - term low - molecular - weight
heparin versus usual care in
proximal - vein thrombosis patients with
cancer . -
pubmed
PURPOSE : A substantial clinical need exists for an alternative to
vitamin K antagonists for treating
deep - vein thrombosis in
cancer patients who are at high risk of both recurrent
venous thromboembolism and
bleeding . -
pubmed
SUBJECTS AND METHODS :
Subjects were
patients with
cancer and acute symptomatic
proximal - vein thrombosis . -
pubmed
Bleeding , largely minor , occurred in 27
patients ( 27 % ) receiving
tinzaparin and 24
patients ( 24 % ) receiving usual care ( absolute difference -3.0 ; 95 % CI , -9.1 to 15.1 ) . -
pubmed
In
patients without additional risk factors for
bleeding at the time of randomization , major
bleeding occurred in 0 of 51
patients ( 0 % ) receiving
tinzaparin and 1 of 48 patients ( 2.1 % ) receiving usual care . -
pubmed
CONCLUSION : Our findings confirm the limited but benchmark data in the literature that long - term low - molecular - weight
heparin is more effective than
vitamin - K - antagonist therapy for preventing recurrent
venous thromboembolism in
patients with
cancer and proximal
venous thrombosis . -
pubmed
These results indicate that
ischaemia activates caspases shortly after reperfusion and that the sex of the
animal may strongly influences apoptotic pathways in the pathogenesis of
neonatal brain injury . -
pubmed
METHODS : This retrospective review examined 207 normal eyes of
patients undergoing an initial consultation for primary refractive surgery and 42 eyes with clinical
keratoconus (
KCN ) . -
pubmed
METHODS : Two blinded trained observers scored 95 AS radiographs from a cohort of
AS patients . -
pubmed
SELECTION CRITERIA : Randomized trials comparing antibiotic treatment with placebo or no treatment in pregnant
women with asymptomatic
bacteriuria found on antenatal screening . -
pubmed
RESULTS : Desaturation developed during 1 procedure , and there was
hypotension in 5
patients . -
pubmed
In addition ,
cardiac arrest occurred intraoperatively in 1
patient , which was the only fatality . -
pubmed
Five months after presentation ,
decreased vision and
epiretinal membrane formation associated with development of a full - thickness
macular hole were observed in the first
patient . -
pubmed
In the second
patient , a full - thickness
macular hole was demonstrated by optical coherence tomography 6 weeks after presentation . -
pubmed
Validation of the BrockTB stat - pak assay for detection of
tuberculosis in
Eurasian badgers (
Meles meles ) and influence of disease severity on diagnostic accuracy . -
pubmed
A lateral - flow immunoassay ( BrockTB Stat - Pak ) for detecting
tuberculosis in
Eurasian badgers was 49 % sensitive and 93 % specific against culture for
M. - pubmed
METHODS : Nine
patients with acute
hyperlipidemic pancreatitis were treated with DFPP in addition to the conventional therapeutic measures . -
pubmed
CONCLUSION : DFPP can be effectively and safely applied in
patients with acute
hyperlipidemic pancreatitis . -
pubmed
METHODS : Thirty - nine
patients with
HCM underwent cine steady - state , free - precession and delayed contrast - enhanced , inversion - recovery , gradient - echo MRI . -
pubmed
RESULTS : Among the 39
patients , 2 showed
apical aneurysm and 17 showed apical thinning . -
pubmed
A few
patients with apical thinning had some common features to apical
aneurysm such as myocardial apical myocardial hyperenhancement . -
pubmed
Early childhood
infection by
human herpesvirus 8 in Zambia and the role of
human immunodeficiency virus type 1 coinfection in a highly endemic area . -
pubmed
Kaposi ' s sarcoma occurs at high incidence among Zambian adults and children , but there is a paucity of data on
human herpesvirus 8 (
HHV-8 ) incidence and routes of
infection , especially in children . -
pubmed
The incidence rate of
HHV-8 seroconversion was 13.8
infections per 100 child - years by 48 months of age . -
pubmed
Maternal
HIV-1 and
HHV-8 infection status were not independently associated with risk of
HHV-8 seroconversion in the child . -
pubmed
Despite a long history of widespread use , objective evidence that administration of
sodium bicarbonate improves outcomes for
patients in
cardiopulmonary arrest or with
metabolic acidosis is lacking . -
pubmed
One
patient with closed
wounds had transient
hypotony along with shallow peripheral choroidals noted on postoperative day 1 , which resolved on their own . -
pubmed
MATERIALS AND METHODS : We present a case of a 55 - year - old
man who was having
ischemic symptoms related to severe
middle cerebral artery stenosis . -
pubmed
Current recommended dosing of
vancomycin for
children with invasive
methicillin - resistant
Staphylococcus aureus infections is inadequate . -
pubmed
BACKGROUND :
Vancomycin area - under - the - concentration - time - curve ( AUC ) for 24 hours divided by the minimum inhibitory concentration ( MIC ) ( AUC24 / MIC ) & gt;400 optimally treats invasive
methicillin - resistant
Staphylococcus aureus (
MRSA )
infections in adults . -
pubmed
CONCLUSIONS : A
vancomycin dose of 40 mg / kg / d in
children is unlikely to achieve the recommended pharmacodynamic target of AUC24 / MIC & gt;400 for invasive
MRSA infections even when MIC is 1.0 microg / mL. -
pubmed
Sepsis affects 40 % of critically ill
patients , with a reported mortality of approximately 30 % in severe
sepsis , raising to 75 % when
acute kidney injury ensues , which occurs in about 20 - 51 % of cases . -
pubmed
The present study consists on a one - year prospective , observational , longitudinal trial undergone in 80 severe septic
patients to determine the risk of development of
acute kidney injury and its relationship with mortality ; the association of the clinical course and blood parameter variations with mortality ; the severe
sepsis mortality rate ; an eventual correlation between
death and septic focus , and to assess mortality predictibility based on initial
creatinine levels and final variations . -
pubmed
OBJECTIVE : To establish differential protein expression profile specific for serum proteome of
cervical carcinoma in Uighur
women by protein 2 - dimensional liquid phase chromatography . -
pubmed
CONCLUSION : Two - dimensional liquid phase chromatography is an effective and feasible method to establish differential expression profile of serum proteome and to offer a new way for the screening of serum protein markers of Uighur
women with
cervical carcinoma . -
pubmed
PURPOSE : To describe retrospectively the overall survival , the
cancer specific survival and the
tumor control in an homogeneous series of
patients with
epidermoid carcinoma of the anal canal treated with definitive radiotherapy ; to assess the impact of brachytherapy , chemotherapy and pre - radiotherapy resection on the risk of
recurrence . -
pubmed
Five
patients recurred ( 5 - year rate : 12 % : four had local
relapse ( 5 - year rate : 8 % ) , four had groin
recurrence , and distant
metastases were seen in two . -
pubmed
In univariate analysis , the risk of
relapse was higher in
patients who had undergone a pre - radiation excision ( p=0.018 ) , in those who did not receive chemotherapy ( p=0.076 ) and in those who were irradiated on a belly board ( p=0.049 ) . -
pubmed
CONCLUSION : Radiotherapy and chemoradiation with
cisplatine - based chemotherapy cure a vast majority of
patients with
epidermoid carcinoma of the anal canal . -
pubmed
Patients with
perivenous demyelination ( n = 13 ; median age 43 years , range 5 - 67 ) on brain biopsy and/or autopsy , ascertained retrospectively , were compared with a cohort with confluent
demyelination only ( n = 91 ; 84 %
multiple sclerosis , 16 % isolated
syndrome at follow - up ; median age 39 years , range 10 - 69 ) . -
pubmed
Among the
perivenous demyelination cohort , 10
patients had only perivenous
demyelination and three also had confluent
demyelination . -
pubmed
All but one
patient with
perivenous demyelination only had a monophasic course , whereas two of three with both types had a relapsing course . -
pubmed
A distinct pattern of cortical microglial activation and aggregation without associated
cortical demyelination was found among six
perivenous demyelination patients , all of whom had
encephalopathy and four of whom had depressed level of consciousness . -
pubmed
This pattern of cortical pathology was not observed in the confluent
demyelination cohort , even in one
patient with
depressed level of consciousness . -
pubmed
Clinical criteria were 80 % sensitive and 91 % specific for pathologically defined
acute disseminated encephalomyelitis (
perivenous demyelination ) , but misdiagnosed
acute disseminated encephalomyelitis among 9 % of
patients with confluent
demyelination and
multiple sclerosis diagnosis at last follow - up . -
pubmed
Depressed level of consciousness is a more specific clinical criterion for pathologically confirmed
acute disseminated encephalomyelitis than
encephalopathy , which over - diagnosed
acute disseminated encephalomyelitis among
multiple sclerosis patients . -
pubmed
Although pathological evidence of
perivenous demyelination may be superior to clinical criteria for diagnosing
acute disseminated encephalomyelitis , the co - occurrence of perivenous and confluent
demyelination in some
individuals suggests pathogenic overlap between
acute disseminated encephalomyelitis and
multiple sclerosis and misclassification even with biopsy . -
pubmed
In 1990 - 2006 Tashkent Medical Academy Clinic admitted 71 patients ( 63
boys and 8
girls ) with subtotal and total forms of
epispadia which in some cases combined with
extrophy of the bladder . -
pubmed
The aim of the study was to evaluate the role dynamic magnetic resonance imaging defecography , and to elucidate the underlying anatomic and pathophysiologic background of
pelvic floor disorders in these
patients in order to minimize failures . -
pubmed
RESULTS : The dynamic MRI of the pelvic floor showed 23
patients with descending perineum , 32
rectoceles ( 28 females ) , 12
cystoceles ( 10 females ) , 6
enteroceles ( 4 females ) , 18
intussusceptions ( 14 females ) , and 7
dyskinetic puborectalis muscle ( 3 females ) . -
pubmed
The diagnosis of combined
pelvic floor disorders with dynamic MRI defecography was consistent with clinical results in 70 % and there were additional diagnostic parameters in 30 % of
patients . -
pubmed
METHODS : The antitumour activities and related mechanisms of
WP1066 were investigated in vitro on
renal cancer cell lines and in vivo on
murine xenografts . -
pubmed
Pilot study of a combination of S-1 and
paclitaxel for
patients with peritoneal
metastasis from
gastric cancer . -
pubmed
BACKGROUND : This pilot study was carried out to evaluate the efficacy of chemotherapy for
patients with peritoneal dissemination from
gastric cancer or positive lavage cytology diagnosed by staging laparoscopy . -
pubmed
After five courses of this therapy , the primary
gastric tumors were evaluated and second - look laparoscopy was performed for
patients showing partial response or stable disease with clinical benefit . -
pubmed
No viable
cancer cells were detected on cytopathological investigation during second - look laparoscopy in 9
patients who underwent surgical treatment . -
pubmed
Leucopenia of grade 3 and
neutropenia of grade 3 were recognized in two and three
patients , respectively . -
pubmed
We plan to study this regimen further in
gastric cancer patients with peritoneal dissemination . -
pubmed
Bilirubin and its oxidative metabolite
biopyrrins in
patients with
acute myocardial infarction . -
pubmed
This study aimed to assess the involvement of
bilirubin and its oxidative metabolite
biopyrrin in
patients with
acute myocardial infarction (
AMI ) and to determine the responsible organs that overproduce these molecules . -
pubmed
One hundred thirteen consecutive
patients hospitalized for
AMI were analyzed . -
pubmed
Serum
bilirubin and its metabolite
biopyrrins were elevated in
patients with
AMI . -
pubmed
Polarization - based linear birefringence is measured on the myocardium of adult
rat hearts after
myocardial infarction and compared with hearts that had received mesenchymal stem cell treatment . -
pubmed
Based on the pharmacokinetics of
nitroxides in
mice , half - life mapping was demonstrated in an
ischemia - reperfusion model
mouse brain . -
pubmed
BACKGROUND : Dysregulated expression of microRNAs ( miRNAs ) has been previously observed in
human cancer tissues and shown promise in defining
tumor status . -
pubmed
Clinical isolates were collected from throughout the US from
dogs ( n=157 ) or
cats ( n=43 ) with naturally occurring
infection between March 2008 and January 2010 . -
pubmed
Advantages of radio frequency ( RF ) cone biopsy compared to large loop excision of the transformation zone ( LLETZ ) in
patients with
high - grade squamous intraepithelial lesions : a retrospective study . -
pubmed
OBJECTIVE : The aim of this study was to compare radio wave cone biopsy to the LLETZ method in
patients with
high - grade squamous intraepithelial lesions . -
pubmed
METHOD - RESULTS : This was a retrospective study of 186
patients diagnosed with
HGSIL who underwent cone biopsy either with the LLETZ method ( 82/186 ) or with the radio wave method ( 104/186 ) in the 2nd Obstetrics and Gynecology Department , University of Athens , Aretaieion Hospital , Athens , Greece during the period January 1999 to December 2008 . -
pubmed
Histopathological analysis revealed focal or extensive
high - grade squamous intraepithelial neoplasia extending into the underlying endocervical glands in 128/186
patients . -
pubmed
Concomittent
low - grade squamous intraepithelial lesions were observed in 160/186
patients and
coilocytic atypia was observed in 172/186
patients . -
pubmed
Zebrafish as a genomics model for
human neurological and
polygenic disorders . -
pubmed
While in model
organisms such as the
zebrafish , mutants are sought that disrupt the function of individual genes ,
human mutations that cause , or are associated with , the development of
disease , are often not acting in a Mendelian fashion , are frequently of small effect size , are late onset , and may reside in noncoding parts of the genome . -
pubmed
A critical advantage is the ease of
zebrafish transgenesis , both for the testing of
human regulatory DNA driving expression of fluorescent reporter proteins , and the expression of mutated disease - associated
human proteins in specific neurons to rapidly model aspects of
neurological disorders . -
pubmed
Potential drug development candidates for
human soil - transmitted helminthiases . -
pubmed
While generally safe and effective in reducing intensity of
infection , they are contra - indicated in first - trimester pregnancy and have suboptimal efficacy against
Trichuris trichiura . -
pubmed
Neoadjuvant therapy was used in 57.1 % of
patients with
carcinoma . -
pubmed
METHODS : Twenty - three adolescent
girls with
epilepsy aged from 8 to 14 years were treated with
VPA for 1 year . -
pubmed
CONCLUSIONS :
VPA treatment for 1 year does not increase serum levels of
androgen in adolescent
girls with
epilepsy , suggesting that
VPA is an ideal choice of treatment for the
girls . -
pubmed
Among groups of herring injected with
VHSV , the prevalence of
infection was dose - dependent , ranging from 100 % , 75 % and 38 % after exposure to 19 , 0.7 and 0.07 plaque - forming units ( PFU)/fish , respectively . -
pubmed
Among
Pacific herring exposed to waterborne
VHSV ( 140 PFU mL(-1 ) ) , the prevalence of
infection , geometric mean viral tissue titre and cumulative mortality were greater among cohabitated herring than among cohorts that were held in individual aquaria , where fish - to - fish transmission was prevented . -
pubmed
INTRODUCTION : Up to one in five
people may have generalised
anxiety disorder (
GAD ) at some point , and most have other health problems . -
pubmed
Cortical
blindness in a
child with acute
glomerulonephritis . -
pubmed
The association between
hypertensive encephalopathy and
cortical blindness in
children with acute
glomerulonephritis is extremely rare . -
pubmed
We analyzed the electrophysiological features in four
patients from Brazil who fulfilled the clinical criteria for
SPS . -
pubmed
The clinicoradiologic findings and histological analysis of
mandibular lesions in two
patients who reported at the Dental Centre of the University College Hospital , Ibadan , Nigeria , are presented . -
pubmed
The two
patients were diagnosed of
mandible osteosarcoma occurring concurrently with bilateral mandibular focal
cemento - osseous dysplasia . -
pubmed
Facial and vocal affect perception in
people at ultra - high risk of
psychosis , first - episode
schizophrenia and healthy controls . -
pubmed
METHODS : Seventy - nine ultra - high risk
patients , 30 first - episode
schizophrenia patients and 30 healthy control subjects completed a facial affect labelling test and an affective prosody recognition test . -
pubmed
Establishing a brain -
death donor model in
pigs . -
pubmed
INTRODUCTION : An
animal model that imitates
human conditions might be useful not only to monitor pathomechanisms of
brain death and biochemical cascades but also to investigate novel strategies to ameliorate organ quality and functionality after multiorgan donation . -
pubmed
METHODS :
Brain death was induced in 15
pigs by inserting a catheter into the intracranial space after trephination of the skull and augmenting intracranial pressure until
brain stem herniation . -
pubmed
All 15
animals showed typical signs of
brain death such as
diabetes insipidus ,
hypertensive and
hypotensive periods , as well as
tachycardia . -
pubmed
DISCUSSION :
Brain death can be induced in a
pig model by inserting a catheter after trephination of the skull . -
pubmed
According to standard guidelines the brain -
death diagnosis was established by a flat - line EEG , which occurred in all
animals at 60 minutes after induction . -
pubmed
Efficacy , pharmacokinetics , and safety of
adalimumab in pediatric
patients with
juvenile idiopathic arthritis in Japan . -
pubmed
The objective of this study was to evaluate the efficacy , pharmacokinetics , and safety of
adalimumab in
patients with
polyarticular juvenile idiopathic arthritis (
JIA ) in Japan . -
pubmed
Six
patients ( all with
MTX ) experienced nine serious AEs (
JIA ,
pyrexia ,
arthralgia ,
pneumonia ,
hepatitis B infection ,
pharyngitis ,
dehydration ,
pharyngeal pain , and
pneumonia ) . -
pubmed
In pediatric
patients with
polyarticular JIA in Japan ,
adalimumab was safe and effective for reducing disease activity for up to 60 weeks . -
pubmed
Genes associated to antibiotic resistance and microbial virulence previously identified in organisms with
human health significance were detected in these aeromonads , suggesting that these waters may act as a pivotal route for
infections . -
pubmed
Thirty
children ( 60 ears ) , 2 - 16 years old ( mean age 7.06 + - 2.77 years ) who were planned to undergo surgical intervention for
bilateral otitis media with effusion (
OME ) , were included in this study . -
pubmed
Both ears were examined intraoperatively for
bleeding , and
patients were evaluated for
myringosclerosis formation with otomicroscopy at the end of the ninth month . -
pubmed
Salmonella typhi is a pathogen that causes the
human disease of
typhoid fever . -
pubmed
We also highlight the importance of autonomic cardiac control in psychiatric disorders of
social dysfunction and suggest that heart rate variability ( HRV)-an index of autonomic cardiac control - may play a key role in
patient response in treatment trials of
OT . -
pubmed
The investigated material comprised ileum sections sampled from
piglets ( aged 8 - 10 weeks ,
body weight of 15 - 18 kg ) on days 14 , 28 and 42 of the experiment . -
pubmed
Although the survival of
lung cancer patients has improved significantly due to the development of early detective tools ,
lung cancer remains a leading cause of
cancer - related
death after curative surgery . -
pubmed
So it is extremely important for
cancer patients to predict early
metastasis , especially pleural dissemination , the most frequent type of recurrence in
patients after surgery . -
pubmed
During the median 27 months of postoperative surveillance , 16 of the 81
patients died , and 9 of the 16 developed pleural
metastases . -
pubmed
Epidemiology is the study of the causes and distributions of
diseases in
human populations so that we may identify ways to prevent and control disease . -
pubmed
Economic study : a cost - effectiveness analysis of an intraoperative compared with a preoperative image - guided system in lumbar pedicle screw fixation in
patients with
degenerative spondylolisthesis . -
pubmed
In this article , we present a long - term observation of a
patient with
Goldenhar syndrome . -
pubmed
Altered expression of glial and synaptic markers in the anterior hippocampus of behaviorally
depressed female
monkeys . -
pubmed
We reported reduced neuropil volume and number of glia in the dentate gyrus ( DG ) and cornu ammonis ( CA)1 of the anterior hippocampus in behaviorally
depressed adult female
cynomolgus macaques . -
pubmed
OBJECTIVE : To study the impact of
tamoxifen on overall survival ( OS ) compared to best supportive care ( BSC ) in Egyptian
patients with advanced
HCC . -
pubmed
CONCLUSIONS :
Tamoxifen did not show any OS advantage in Egyptian
patients with advanced
HCC . -
pubmed
We describe a 62 - year - old
male who was suffering from advanced
prostatic malignancy , taking
amiodarone for underlying
heart disease . -
pubmed
We have shown that , after severe
trauma ,
obese Zucker ( OZ )
rats , similar to
obese patients , exhibit increased
acute lung injury compared with lean Zucker ( LZ )
rats . -
pubmed
We hypothesized that OZ
rats exhibit a greater increase in early
posttrauma glucose compared with LZ
rats , with the increased posttrauma
hyperglycemia suppressed by ICI treatment . -
pubmed
Orthopedic trauma was applied to both hindlimbs in LZ and OZ
rats . -
pubmed
Lung wet - to - dry weight ratios were increased in OZ
rats but not in LZ
rats . -
pubmed
showed that the amount of circulating TEMs is higher in
hepatitis virus C (
HCV)/
HCC patients compared to
HCV patients or healthy subjects . -
pubmed
DESIGN : This was a crossover feeding study in 11
CKD participants ( estimated
glomerular filtration rate : 30 - 45 mL min(-1 ) 1.73 m(-2 ) ) and 4 healthy control subjects . -
pubmed
RESULTS : In
CKD participants who consumed the high -
phosphate diet , there were circadian changes in
phosphate with lowest concentrations ( + - SDs ) at 0800 ( 4.2 + - 0.5 mg / dL ) and 2 peaks at 1600 and 0400 ( 4.5 + - 0.8 and 4.4 + - 0.6 mg / dL , respectively ) , which were similar to those in healthy controls . -
pubmed
Unencapsulated
Streptococcus pneumoniae from
conjunctivitis encode variant traits and belong to a distinct phylogenetic cluster . -
pubmed
Streptococcus pneumoniae , an inhabitant of the upper respiratory mucosa , causes
respiratory and invasive infections as well as
conjunctivitis . -
pubmed
Here we perform a comparative genomic analysis of 271
strains of
conjunctivitis - causing
S. - pubmed
These findings suggest that the unencapsulated
strains capable of causing
conjunctivitis utilize a pathogenesis strategy substantially different from that described for
S. - pubmed
Radiofrequency catheter ablation of
atrial fibrillation in
patients with
chronic obstructive pulmonary disease : opportunity and challenge : response to Dr. Kumar 's comment . -
pubmed
Regulation of gene expression in
HBV- and
HCV - related hepatocellular carcinoma : integrated GWRS and GWGS analyses . -
pubmed
OBJECTIVES : To explore the molecular mechanism of
hepatitis B virus - related and
hepatitis C virus - related
hepatocellular carcinoma , samples from
hepatitis B virus and hepatitis C virus infected patients and the normal were compared , respectively . -
pubmed
CONCLUSION : The analysis above helped us to understand the pathogenesis of
hepatitis B virus and
hepatitis C virus associated hepatocellular carcinoma . -
pubmed
METHODS :
Patients with
inguinal / femoral hernias from February 2013 to February 2014 undergoing SILTEP herniorraphy with telescopic dissection were compared with
patients who had previously undergone SILTEP herniorraphy with balloon dissection . -
pubmed
METHODS : This prospective interventional study enrolled 14
patients ( 18 eyes ) with progressive
keratoconus who underwent CXL with an ultraviolet - A irradiation intensity of 18 mW / cm for 5 minutes . -
pubmed
RESULTS : No intraoperative or
postoperative complications were observed in any of the
patients . -
pubmed
Since there are concerns regarding HAART - mediated onset of
cardio - metabolic diseases in the long - term , we evaluated the anthropometric profile of black
HIV - infected individuals in a peri - urban setting ( Western Cape , South Africa ) . -
pubmed
METHODS : This was a retrospective study of 160
subjects with
CMT who had undergone neck MRI at the age of 48 months or younger at a tertiary medical center . -
pubmed
, ratios of area and intensity , may provide a guideline for deciding the need for surgical intervention in
CMT patients . -
pubmed
METHODS : This was a nested case - control study of
women who had undergone second - trimester screening for
fetal aneuploidy and had banked serum available for analysis . -
pubmed
RESULTS : We identified 51 cases of severe
preeclampsia from our population of 3,992
women ( 1.3 % ) , of whom 33 had sufficient serum for analysis . -
pubmed
Median
paraxanthine concentrations were not significantly higher in
women in the control group than women in the case group ( 96.4 ng / mL compared with 38.0 ng / mL , P=.12 ) , and higher serum
paraxanthine was not associated with lower odds of severe
preeclampsia ( odds ratio [ OR ] 0.72 , confidence interval [ CI ] 0.48 - 1.08 ) . -
pubmed
Different members of the Mycobacterium genus have evolved to cause
tuberculosis in diverse
human populations and in a variety of animal species . -
pubmed
bovis
strain that is able to transmit between
humans or polymorphisms in
M. - pubmed
Whole genome sequencing identifies circulating Beijing - lineage
Mycobacterium tuberculosis strains in Guatemala and an associated urban outbreak . -
pubmed
Here we report the first whole genome sequencing of Central American Beijing - lineage
strains of
Mtb . -
pubmed
Transplantation of olfactory ensheathing cells promotes partial recovery in
rats with experimental
autoimmune encephalomyelitis . -
pubmed
METHODS :
EAE models were established by
guinea pig spinal cord homogenate ( GPSCH ) immunization in Lewis
rats . -
pubmed
OECs were purified and cultured from the olfactory nerve layer of SD
rats , and then transplanted to the
EAE models through the vena caudalis ( Group A ) or into the lateral cerebral ventricle ( Group B ) . -
pubmed
Neurological function scores and body weights were daily recorded following transplantation , and histological analysis was performed to assess the pathological changes in
EAE rats . -
pubmed
Neurological function scoring and the
body weight measurement showed that , OEC transplantation could significantly improve the performance of
EAE rats , and similar results were observed for the transplantation through the vena caudalis and into the lateral cerebral ventricle . -
pubmed
Moreover , the transplanted OECs accumulated to the lesions in the brains of
EAE rats , in spite of the different transplantation approaches . -
pubmed
METHODS : Case - control study of 112
patients with advanced
ovarian cancer submitted to chemotherapy during the period from January 1995 to December 2005 . -
pubmed
Nondiabetic kidney diseases in
type 2 diabetic patients . -
pubmed
BACKGROUND : The aim of this study was to evaluate the clinical characteristics of
nondiabetic nephropathy in
type 2 diabetes mellitus patients and to find a clinical significance of renal biopsy and immunosuppressive treatment in such a
patient . -
pubmed
METHODS : Renal biopsy results , clinical parameters , and renal outcomes were analyzed in 75
diabetic patients who underwent kidney biopsy at Chungnam National University Hospital from January 1994 to December 2010 . -
pubmed
CONCLUSION : Renal biopsy should be recommended for
type 2 diabetic patients with atypical
nephropathy because a considerable number of these
patients may have
nondiabetic nephropathies . -
pubmed
And intensive treatment including
corticosteroid or immunosuppressants could be recommended for
type 2 diabetic patients with
nondiabetic nephropathy , especially if the
patients do not have
diabetic retinopathy . -
pubmed
The primary endpoint was mortality , after exclusion of
patients with metastatic
cancer during follow - up . -
pubmed
Previous studies have revealed that treatment with BM - MSCs may modulate immune responses and alleviate the symptoms in experimental
autoimmune encephalomyelitis (
EAE )
mice , an
animal model of
multiple sclerosis . -
pubmed
Following three passages , BM - MSCs were injected intraperitoneally into
EAE mice alone or in combination with
rapamycin . -
pubmed
Maternal
Obesity in the
Mouse Compromises the Blood - Brain Barrier in the Arcuate Nucleus of Offspring . -
pubmed
Effect of Electroacupuncture on
Inflammation in the Obese Zucker Fatty
Rat Model of
Metabolic Syndrome . -
pubmed
Metabolic syndrome (
MetS ) is a major and escalating public health and clinical challenge worldwide , and
patients with
MetS have an increased risk of developing
cardiovascular disease and
type 2 diabetes mellitus . -
pubmed
Electroacupuncture ( EA ) was tested as a means of decreasing
inflammation in genetically
obese Zucker fatty
rats , which serve as a model of
MetS. -
pubmed
Compared with the control
animals , no significant change in
body weight occurred . -
pubmed
Modeling
lymphangiosarcoma in
mice . -
pubmed
Patients were divided into two groups : with
atherosclerosis and without . -
pubmed
PATIENTS AND METHODS : Forty
patients with mucinous appendiceal
tumors and
PMP were clinically eligible and had evaluable
tumor samples obtained after CRS and HIPEC . -
pubmed
RESULTS AND CONCLUSION : On 2 days after cessation of
CCl4 administration , higher
fibrosis was observed in KO
mice than in WT
mice by Sirius Red staining . -
pubmed
Hydroxyproline contents and
Sirius Red staining showed that repair of
liver fibrosis in the recovery stages appeared to be delayed in KO
mice . -
pubmed
Among the many
stilbenoids found in a variety of
berries ,
resveratrol and
pterostilbene are of particular interest given their potential for use in
cancer therapeutics and prevention . -
pubmed
Breast cancer (
BC ) is the most common
female malignancy within the spectrum of
human cancer . -
pubmed
Patients with a higher NLR had a shorter
disease - free survival ( hazard ratio = 1.46 , 95 % confidence interval : 1.12 - 1.90 , P=0.044 ) and overall survival ( hazard ratio = 2.03 , 95 % confidence interval : 1.41 - 2.93 , P<0.001 ) . -
pubmed
In the luminal A and luminal B subtypes , we found that there was no association between the NLR and overall survival in the
BC patients . -
pubmed
Utility and safety of
tolvaptan in
cirrhotic patients with
hyponatremia : A prospective cohort study . -
pubmed
Hyponatremia is common in
patients with decompensated
cirrhosis and is associated with increased mortality . -
pubmed
MATERIAL AND METHODS : We studied the usage and safety of
tolvaptan in
cirrhotic patients in a real - life , non - randomized , multicenter prospective cohort study . -
pubmed
Forty - nine
cirrhotic patients with
hyponatremia were treated with
tolvaptan 15 mg daily , and 48
patients not treated with
tolvaptan in the same period served as controls . -
pubmed
No
patient with normal serum
sodium on day 7 died within 30 days of treatment , whereas 16 % of those with persistent
hyponatremia died ( p = 0.0019 ) . -
pubmed
CONCLUSION : In conclusion , short - term
tolvaptan treatment is safe and can improve serum
sodium level in cirrhotic
patients with
hyponatremia . -
pubmed
Enhancer of polycomb coordinates multiple signaling pathways to promote both
cyst and germline stem cell differentiation in the
Drosophila adult testis . -
pubmed
Six of the 25
patients died after
AMI . -
pubmed
In addition , 10 of the 25
patients developed in - hospital
AMI after surgery . -
pubmed
Thus the
strain isolated from the Dokdo Island is proposed as a novel species ,
Tetramitus dokdoensis n. sp . -
pubmed
The role of
hydrogen sulfide (
H2S ) in
portal hypertension ( PH)-induced
esophagus - gastric junction vascular lesions in
rabbits was observed . -
pubmed
T - Cell Mediation of Pregnancy Analgesia Affecting Chronic
Pain in
Mice . -
pubmed
Using an inflammatory ( complete Freund 's adjuvant ) or
neuropathic ( spared nerve injury ) model of persistent
pain , we observed that young adult female
mice in early pregnancy switch from a microglia - independent to a microglia - dependent
pain hypersensitivity mechanism . -
pubmed
During late pregnancy , female
mice show no evidence of chronic
pain whatsoever . -
pubmed
This pregnancy - related analgesia has been demonstrated for acute
pain in
rats . -
pubmed
Here , we show that pregnancy analgesia can produce a complete cessation of chronic
pain behaviors in
mice . -
pubmed
Changes in Signal Intensity of the Dentate Nucleus and Globus Pallidus in Pediatric
Patients : Impact of Brain Irradiation and Presence of Primary
Brain Tumors Independent of Linear
Gadolinium - based Contrast Agent Administration . -
pubmed
Materials and Methods This institutional review board - approved , HIPAA - compliant study included 144 pediatric
patients who underwent intravenous
GBCA - enhanced MR imaging examinations ( 55
patients with primary
brain tumors and whole - brain irradiation , 19 with primary
brain tumors and chemotherapy only , 52 with primary
brain tumors without any treatment , and 18 with
neuroblastoma without
brain metastatic disease ) . -
pubmed
Hafnia alvei : A new pathogen in open
fractures . -
pubmed
Hafnia alvei is an unusual pathogen that is rarely pathogenic in
humans and has never been reported as a cause of
infection following open
fracture . -
pubmed
Conclusions : This is the first report of
deep infection following an open
forearm fracture owing to
Hafnia alvei , a pathogen rarely responsible for
human infection . -
pubmed
A few drugs and drug combinations are used in the treatment of canine
babesiosis often without complete parasite elimination leaving treated
dogs as carriers which could relapse with clinical disease and also transmit
infection further . -
pubmed
Zebrafish Models of Rare
Hereditary Pediatric Diseases . -
pubmed
A plethora of genetic tools makes it easy to create mutations in almost any gene of the
zebrafish genome and these mutant
strains can be used in high - throughput preclinical screens for active molecules . -
pubmed
A total of 768 1 - d - old Ross 308 male
broiler chickens with an average
body weight of 43.64 + - 0.59 g were used in a 5 - wk feeding trial . -
pubmed
During
sepsis , disturbed gastrointestinal motility and increased mucosal permeability can aggravate
sepsis due to the increased risk of
bacterial translocation . -
pubmed
To help identify new therapeutic targets , there is a need for
animal models that mimic the immunological changes in the gastrointestinal tract as observed during
human sepsis . -
pubmed
Brachycephalic airway syndrome (
BAS ) is characterized by increased upper airway resistance due to conformational abnormalities occurring in
brachycephalic dogs ( BD ) . -
pubmed
In this prospective study , we evaluated
pulse oximetry ( SpO2 ) and arterial blood gas values in 18 healthy BD and compared these values with those of 18 healthy mesocephalic and dolichocephalic
dogs (
MDD ) . -
pubmed
PATIENTS AND METHODS : We performed a retrospective analysis of the data of 319
patients [ 123 ( 36.6 % ) female and 196 ( 61.4 % ) male ] who had
colorectal cancer and underwent surgery to treat
colorectal liver metastases in our Department between 2005 and 2014 . -
pubmed
METHODS : Twenty - five
subjects with
anterior mediastinal lesions suspicious for
malignancy were enrolled in an open - label feasibility trial . -
pubmed
Among the
subjects with solid
tumors , 19 of 20 accumulated
ICG . -
pubmed
METHODS : A total of 50 consecutive
patients with
pancreatic / periampullary cancer who underwent PD between January 2016 to August 2017 were included in the study . -
pubmed
The aim of this study was to evaluate the agreement of EDX and MRI in
patients with
brachial plexopathy . -
pubmed
DESIGN : The records of 69
patients with symptoms of
brachial plexopathy who underwent EDX and MRI were reviewed . -
pubmed
MATERIALS AND METHODS : The study was carried out in
vac - cine strain Y pestis EV76 ( pMT1 , pCD1 , pPCP1 ) and non - plasmid variants of vaccine
EV76 ( pMT1- , pCD1- , pPCP1- ) and virulent 231 ( pMT1- , pCD1- , pPCP1- )
strains of
Y pestis . -
pubmed
Presence of functionally active form of lipopolysaccharide ( LPS ) in.the incubation medium of the
bacteria was evaluated via toxicity of supernatant of
Y pestis for intactanimals ( infec- tion -
toxic shock ) and
mice sensitized by
D - GalN. -
pubmed
Non - plasmid variants of both vaccine and virulent
strains of
Y.pestis pMT- , pCD1- , pPCP1- do not have this ability . -
pubmed
Individuals with end - stage
diabetic peripheral neuropathy present with decreased
pain sensation . -
pubmed
Myocardial extracellular volume fraction measurements with MOLLI 5(3)3 by cardiovascular MRI for the discrimination of healthy
volunteers from dilated and
hypertrophic cardiomyopathy patients . -
pubmed
RESULTS :
DCM and
HCM patients had significantly higher myocardial native T1 times and ECVs than healthy volunteers ( p<0.001 ) . -
pubmed
At the optimal cut - off value , ECV identified
DCM and
HCM patients with 80.7 % and 83.3 % sensitivity , 87.5 % and 70 % specificity , 90.2 % and 67.6 % positive predictive value , and 76.1 % and 84.8 % negative predictive value , respectively . -
pubmed
This study aimed to investigate whether the number of LSAs was associated with the cerebral perfusion in
SVD patients and determine the correlation between the number of LSAs and
SVD severity . -
pubmed
Conclusion : LSA count was lower in
SVD patients than the non - SVD
participants and there was a positive correlation between the cerebral perfusion and the number of LSAs . -
pubmed
This finding may have potentially important clinical implications for monitoring LSA in
SVD patients . -
pubmed
Previously , we used a computational biology approach to define molecular signatures of antiviral DC responses following activation of innate immune signaling or
infection with
West Nile virus (
WNV ) . -
pubmed
Type
strains of
Bacillus halotolerans and
Bacillus mojavensis were grouped into another cluster ( cluster B ) , related to cluster A. -
pubmed
Older patients showed a lower frequency of
FUTI caused by
E. - pubmed
Corneal Refractive Surgery in
Patients with History of
Optic Neuritis . -
pubmed
Purpose : The purpose of this study was to evaluate the risk of
recurrence of
optic neuritis after corneal refractive surgery in
patients with a history of
optic neuritis and to examine the safety and efficacy of the procedure in this population . -
pubmed
Patients were followed - up for over five years postoperatively for the
recurrence of
optic neuritis . -
pubmed
Optic neuritis recurred in 3/15 ( 20 % ) eyes and 3/14
patients ( 21 % ) . -
pubmed
Conclusion : While corneal refractive procedures appear safe in
patients with a history of
optic neuritis , our data suggest that their efficacy may be reduced . -
pubmed
Pleomorphic xanthoastrocytoma (
PXA ) is a relatively rare , low grade
astrocytic tumor that usually affects
children as well as young adults . -
pubmed
PURPOSE : To evaluate different corneal parameters in identifying
patients at risk of a
hyperopic shift after ( DMEK ) . -
pubmed
METHODS : This retrospective study included 92 eyes of
patients with
FECD after DMEK surgery . -
pubmed
In total , 48
girls with
CPP and 35 age - matched prepubertal control
girls were enrolled in the study . -
pubmed
Diabetic nephropathy (
DN ) is one of the leading causes of mortality in
diabetic patients . -
pubmed
Occurrence of
Leaf Spot Disease Caused by
Alternaria crassa ( Sacc . ) -
pubmed
was recovered from
jimson weed ,
tomato ,
parsley , and
coriander collected during surveys of
blight diseases on Solanaceae and Apiaceae in Algeria . -
pubmed
Further the pathogen was evaluated on
jimson weed ,
coriander ,
parsley , and
tomato plants , and this fungus was able to cause
necrotic lesions on all inoculated plants . -
pubmed
The risk factors associated with local
recurrence ( LR ) in
patients receiving preoperative
denosumab for
GCTB also are unknown . -
pubmed
QUESTIONS / PURPOSES : ( 1 ) Is short - course ( three doses or fewer ) preoperative
denosumab treatment as effective as longer course ( more than three doses ) of treatment in terms of achieving a clinical , radiologic , and histologic response in
patients with
GCTB ? -
pubmed
( 2 ) Is there an increased risk of LR after short - course
denosumab therapy compared with long - course
denosumab therapy ; and after controlling for confounding variables , what factors were associated with LR after surgery for
GCTB in
patients receiving preoperative
denosumab ? -
pubmed
METHODS : A retrospective study was performed using an institutional database of 161 skeletally mature
patients with a histologic diagnosis of
GCTB who received
denosumab between November 2010 and July 2019 to downstage the
tumor before surgery . -
pubmed
In general , we used denosumab when we thought it would facilitate either resection or curettage ( by formation of a sclerotic rim around the
osteolytic lesion ) , when a less - morbid procedure than initially planned might be performed , and in
patients with complex presentations like cortical breech and soft tissue extension , pathological
fracture , thinning of more than three cortices of the extremity . -
pubmed
Overall , 77 % ( 37 of 48 ) of
patients taking short - course
denosumab and 75 % ( 27 of 36 ) of
patients on long - course
denosumab underwent curettage , and the remaining
patients with an inadequate bony shell around the
tumor or destruction of articular cartilage in both groups underwent
tumor resection . -
pubmed
With the numbers available , the
patients with short- and long - course
denosumab were not different in terms of age , sex , MSTS score on presentation , lesion size , lesion location , Campanacci grade , presence of pathological
fracture and pulmonary
metastasis on presentation , and the type of surgery performed ( curettage versus resection ) . -
pubmed
We recruited a subsample of 45
children ( mean age 9y 2mo ; SD 2y 7mo ; range 5 - 12y ; 22 males , 23 females ) and collected parental reports of
autism symptomatology , adaptive behavior , and behavioral problems that were compared to those of 360 age- and sex - matched controls from the Simons Simplex Collection ( SSC ) with
autism spectrum disorder (
ASD ;
SSC -
ASD ) or typically developing (
SSC - TD ) . -
pubmed
Immunotherapy has recently emerged as a promising treatment option for
multiple myeloma (
MM )
patients . -
pubmed
Thus , further characterization of the defects present in the immune system of
MM patients is essential to develop novel therapies and to repurpose the existing ones . -
pubmed
In the
patient discussed ,
hyperflexion of the hip results in the engagement of the present CAM lesion , and the resulting subluxation leads to a
fracture of the posterior wall and instability of the hip . -
pubmed
OBJECTIVES : To define pre - morbid , clinical , laboratory , and imaging features and identify prognostic factors associated with morbidity and mortality in
patients with
Emphysematous pyelonephritis (
EPN ) and develop a prognostic scoring system for improving management outcomes . -
pubmed
BA01 , a gut bacterial
strain of the wood ant (
Formica yessensis ) . -
pubmed
METHODS : This retrospective , longitudinal cohort study included consecutive
patients with primary
SS evaluated at a tertiary referral center . -
pubmed
RESULTS : One hundred and twenty - six
SS patients with minimum 3 years of follow - up ( median 9.6 , range 3.0 - 15.9 years , total of 1,235 patient - years ) were included . -
pubmed
The type
strains of
Rhodocytophaga rosea and
Nibribacter ruber are 172606 - 1 T (= KCTC 62096 T = NBRC 114410 T ) and BT10 T (= KCTC 62607 T = NBRC 114383 T ) , respectively . -
pubmed
MATERIALS AND METHODS : The extension of six textural features , including consolidation ( C ) , ground glass opacity ( GGO ) ,
fibrosis ( F ) , low attenuation areas ( LAA ) , reticulation ( R ) and healthy regions ( H ) , was quantified in 27
cHP patients ( age : 56 + - 11.5 years , forced vital capacity [ FVC]% = 57 + - 17 ) acquired at full - inspiration via HRCT . -
pubmed
Some miRNAs have already been found to be closely related to the prognosis of
patients with
OS . -
pubmed
While the proportion of
ischemic stroke patients recommending endovascular treatment ( 14.3 % vs. 14.6 % ; p=0.85 ) remained stable , there was a non - significant trend towards a lower proportion of recommending intravenous thrombolysis during the lockdown ( 19.0 % vs. 22.1 % ; p=0.052 ) . -
pubmed
However , the influence of DAAs on the course of kidney involvement in
HCV - associated mixed
cryoglobulinaemia (
HCV - MC ) has been little studied . -
pubmed
The aim of this study was to analyse the effects of antiviral treatment on kidney prognosis and evolution in
patients diagnosed with
HCV - MC . -
pubmed
Methods : The RENALCRYOGLOBULINEMIC study is an observational multicentre cohort study of 139
patients with
HCV - MC from 14 Spanish centres . -
pubmed
Provided optimal conditions are employed the microtest system described herein should be ideal for in - vitro - analysis of inhibitory or stimulating factors in
cancer patients ' sera . -
pubmed
Complement - dependent antibody
cytotoxicity test of
chicken antibody with
duck complement used against cells of a
Marek ' s disease lymphoma - derived cell line (
MSB-1 ) . -
pubmed
Complement - dependent antibody
cytotoxicity ( CDAC ) against cells of a
lymphoblastoid cell line (
MSB-1 ) derived from
Marek ' s disease lymphoma was investigated in a
chicken antibody system using complements from several animal species . -
pubmed
Cytotoxicity was seldom observed when
rabbit ,
guinea pig , or
chicken complements were used in the presence of hyperimmune
chicken serum against MSB-1 . -
pubmed
With
duck complement , however ,
cytotoxicity was always observed . -
pubmed
A study of acute
hemiplegia in
children . -
pubmed
The initial rate of phagocytosis ,
oxygen consumption rate during phagocytosis , bactericidal capacity against
Escherichia coli , and the granule protein composition of isolated mature - appearing granulocytes were studied in 23
patients with
chronic granulocytic leukemia (
CGL ) with the simultaneous use of normal controls . -
pubmed
The initial rate of phagocytosis was decreased ( p less than 0.05 ) in the
CGL patient group , as were
oxygen consumption rate ( p less than 0.001 ) and bactericidal capacity ( p less than 0.001 ) . -
pubmed
Functional disturbances due to
herpetic keratouveitis in
rabbits were investigated . -
pubmed
This experimental
herpetic keratouveitis in
rabbits appeared similar to Wellings '
ocular syndrome , which is suspected to be of herpetic etiology . -
pubmed
The authors report a 16 - year - old
girl with
mucolipidosis type IV . -
pubmed
However , the presence of
titanium III citrate or
dithiothreitol ( 7.78 mM ) in the medium decreased ( P less than 0.05 ) the
leukotoxicity of
F. - pubmed
Of the 720
patients with
thyroid cancer we saw from 1953 to 1989 , 49 were younger than 20 years at diagnosis , and the female / male ratio was 4.4:1 . -
pubmed
Suspected
vitamin D rodenticide
poisoning in a
dog . -
pubmed
Chickens passively inoculated with these antibodies were protected against
bursal atrophy ,
weight loss , and early mortality when challenged with the virulent
Md5 strain of Marek ' s disease virus (
MDV ) . -
pubmed
This result provides little hope that
Marek ' s disease can be controlled in progeny
chickens by maternal immunity derived from hyperimmunized parents . -
pubmed
The mechanism of
hypocalcemia was assessed prospectively in 10 gastroenterological
hypomagnesemic patients . -
pubmed
In the 4 tested
patients , plasma
1,25 ( OH ) 2D levels were low before , but also after correction of
hypomagnesemia , suggesting that low level of
1,25 ( OH ) 2D might not be due to
hypomagnesemia . -
pubmed
Therefore , treatment with low dosage of
1 - alpha ( OH ) 2D associated with
magnesium chloride repletion can be recommended to restore normal
calcium homeostasis in
patients with
intestinal hypomagnesemia . -
pubmed
We have evaluated the effect of
5 - fluorouracil 600 mg / m2 ,
doxorubicin ( '
Adriamycin ' ) 40 mg / m2 , and
Mitomycin - C 4 mg / m2 (
FAM ) in two groups of
patients with
adenocarcinoma of the oesophagus , as either a preoperative or primary treatment . -
pubmed
Resection was completed in 20
patients , with six hospital
deaths ( 30 % ) . -
pubmed
Of the 14
patients who were discharged from hospital , 8 have died ( median 8 months ) and 6 are alive at 12 to 27 months , with known
recurrence in 1 . -
pubmed
More pharmacokinetic studies are needed in
human drug abuse liability evaluations . -
pubmed
In our Pediatric Haemato - Oncology Unit , 42 young
patients cured of their
malignancy were left with
chronic delta hepatitis . -
pubmed
All nine
patients included in the study ( five
males , mean age : 15 years ) had well - compensated
liver disease , including five cases with active
hepatitis and
cirrhosis . -
pubmed
At the end of the 3rd month of therapy , two
patients with
cirrhosis developed a biochemical exacerbation leading to
hepatic decompensation , which was fatal in one case . -
pubmed
On the other hand , both
patients seroconverted from
hepatitis B e antigen to antibody at the time of exacerbation , suggesting that
liver damage could have been the result of cell - mediated
cytotoxicity to hepatitis B virus antigens . -
pubmed
Occult cancer in
patients with
deep venous thrombosis . -
pubmed
The authors prospectively studied 113 consecutive
patients with deep
venous thrombosis of the lower extremities to determine the most appropriate workup study for searching for a hidden
cancer . -
pubmed
Lung cancer and exposure to
tobacco smoke in the household . -
pubmed
Sera from 75
patients with
warts were tested for antibodies against
human papillomaviruses (
HPVs ) in an immunoelectron microscopy test . -
pubmed
A group of 40 patients ' sera were tested against a pooled suspension of the
HPVs extracted from their
warts and 90 % of the sera were found to be antibody - positive . -
pubmed
In all 9
dogs that underwent tracheal replacement with
PTFE , granulation tissue developed at the anastomoses resulting in
airway obstruction after 3 to 8 weeks . -
pubmed
Ganglion cells were demonstrated by upper biopsy in four of 13 neonates , six of nine infants , and three of six
children . -
pubmed
The two - point rectal mucosal biopsy is useful not only for making definitive diagnosis but also for the selection of the surgical treatment for
patients with
Hirschsprung ' s disease . -
pubmed
Epidemiological aspects of
human cryptosporidiosis . -
pubmed
Twelve
patients with
non - small cell lung cancer had
tumors that were adherent to the vertebral column and clinically suspected of invading the bone . -
pubmed
Three
patients had true
Pancoast ' s syndrome and in the remaining nine the
tumor was located above T6 with the majority in the apex of the chest . -
pubmed
Detailed studies of the decalcified surgical specimen show that the
tumor extended into the cortex in two
patients , periosteum in six , parietal in three , and up to the visceral pleura in one . -
pubmed
Six
patients are alive after 1 to 11 years ( four beyond 5 years ) without evidence of recurrent
tumor and
arthritic pain . -
pubmed
In
patients with
tumors adherent to the vertebral body and no evidence of roentgenographic erosion , the en bloc removal of the lung and the involved portion of the vertebral body is required for complete excision and is associated with long - term survival without sequelae . -
pubmed
The impulse activity of 177 neuronal populations analyzed in different nuclei of the thalamus and striopallidal complex during visual testing for orientation sensitivity in 9
parkinsonian patients , diagnosed and treated with the long - term intracerebral electrodes . -
pubmed
Selection of protein and fat by
diabetic rats following separate dilution of the dietary sources . -
pubmed
Diabetic and normal
rats were allowed to select their diets from separate sources of protein ,
carbohydrate and fat . -
pubmed
Following the determination of baseline intakes ,
diabetic and normal
rats received dietary components in which either the protein ( Experiment 1 ) or fat source ( Experiment 2 ) was diluted by 25 % or 50 % by the addition of cellulose . -
pubmed
Diabetic rats failed to maintain protein intake at both dilution levels , but made up for the loss of protein - derived calories by consuming more fat . -
pubmed
Diabetic rats maintained fat intake at both dilution levels . -
pubmed
Dietary dilutions had no effect on total caloric intakes or body
weight gain of
diabetic rats . -
pubmed
These data suggest that
diabetic rats maintain total caloric intake following dilution of either the protein or fat source of their diets , but defend intake of fat - derived calories more readily than protein - derived calories . -
pubmed
These findings are discussed in terms of the ability of
diabetic rats to solve the metabolic problems associated with their
diabetic condition . -
pubmed
Two TaqI RFLPs in the
human von Willebrand factor gene . -
pubmed
The mutagenic activity of fasting gastric juice was assessed in 123
patients including 18 with normal endoscopic findings , 53
peptic ulceration , 9
gastric cancer , 12
pernicious anaemia and 31 patients who had undergone
peptic ulcer surgery in the past . -
pubmed
No correlation was found between mutagenic activity and
patient age or sex , gastric pH ,
bile acid concentrations or
bacterial counts , intestinal
metaplasia on gastric mucosal biopsy , or intragastric
nitrite . -
pubmed
About 30 % of gastric juice samples showed evidence of a
cytotoxic activity towards the
Salmonella tester strains in the mutation assay . -
pubmed
We describe the clinicopathological features of multiple
hamartoma and
neoplasia syndrome (
Cowden ' s syndrome ) in a 58 year - old
man and in a 56 year - old woman . -
pubmed
Plasmapheresis was used as a complement to conventional therapy in a
patient with
multiorgan failure and
disseminated intravascular coagulation (
DIC ) following
biliary obstruction and
septic cholangitis . -
pubmed
A retrospective study was conducted on 22
patients with
renal pelvic tumor treated at our University Hospital between 1970 and 1984 . -
pubmed
Actinobacillus actinomycetemcomitans in
human periodontal disease . -
pubmed
Recent evidence implicates
Actinobacillus actinomycetemcomitans in the etiology of localized
juvenile periodontitis . -
pubmed
actinomycetemcomitans , evidence incriminating it as a periodontopathogen , its importance in
human nonoral infections , and virulence factors which may be involved in the pathogenesis of
A. - pubmed
The organism can apparently seed from these sites to cause severe
infections throughout the
human body such as
brain abscesses and
endocarditis . -
pubmed
actinomycetemcomitans as an important micro - organism in the etiology of localized
juvenile periodontitis including : ( 1 ) an increased prevalence of the organism in almost all localized juvenile
periodontitis patients and their families compared to other patient groups ; ( 2 ) the observation that localized juvenile
periodontitis patients exhibit elevated antibody levels to
A. - pubmed
actinomycetemcomitans in serum , saliva and gingival crevicular fluid ; ( 3 ) the finding that localized juvenile
periodontitis can be successfully treated by eliminating
A. - pubmed
actinomycetemcomitans from
periodontal pockets ; ( 4 ) histopathologic investigations showing that
A. - pubmed
actinomycetemcomitans invades the gingival connective tissue in localized juvenile
periodontitis lesions ; ( 5 ) the demonstration of several pathogenic products from
A. - pubmed
Virulence of
Pseudomonas infection in burned
rats and
mice . -
pubmed
[ Oxidative phosphorylation in the brain of
rabbits with
atherosclerosis ] . -
pubmed
On the site of action of
nicotine on
contracture in
frog sartorius muscle . -
pubmed
When tested in kindled
animals , both agents showed a transient and non - dose - dependent anticonvulsant effect , in addition to raising the generalized
convulsive seizure - triggering threshold for a prolonged period of time . -
pubmed
Neuronotrophic activities in cerebrospinal fluid of
head trauma patients . -
pubmed
Cerebrospinal fluid was collected from 15
patients with acute
CNS lesions in whom ventricular catheters had been placed to monitor and to facilitate the control of intracranial pressure . -
pubmed
NTFs supporting hippocampal neurons were also detected in extracts of
blood clot obtained from normal
volunteers . -
pubmed
These observations suggested that ( i ) NTFs are detectable in
human CSF after
CNS injury , ( ii ) NTFs appear in response to the
injury itself , and ( iii ) at least some
human NTFs can support the survival in culture of
nonhuman CNS neurons . -
pubmed
The
anemia of
chronic renal failure in
sheep . -
pubmed
To determine the in vivo relevance of uremic inhibitors , increasing amounts of Ep as Ep - rich plasma were infused into six
uremic sheep , and their erythropoietic responses were compared with those of nine normal
sheep receiving similar amounts of Ep - rich plasma . -
pubmed
Three
sheep were studied in both normal and
uremic states . -
pubmed
Ep - rich plasma was obtained from
phenylhydrazine- and phlebotomy - induced
anemic sheep . -
pubmed
Ep - rich plasma stimulated erythropoiesis similarly in uremic and normal
sheep , regardless of the degree of
uremia . -
pubmed
Nondialyzed
uremic sheep responded as well as dialyzed animals . -
pubmed
The
anemia was corrected in the
uremic dialyzed
animals . -
pubmed
The
anemia was corrected in the
uremic sheep after 15 - 40 daily infusions of Ep - rich plasma , the total dosage depending on the severity of the
anemia . -
pubmed
These dose - response effects , coupled with the identical erythropoietic response in normal and
uremic sheep given the same amount of Ep - rich plasma , imply that there are no physiologically significant erythropoietic inhibitors in
uremia . -
pubmed
In comparison with control
animals ( pCO2 = 41.2 mm Hg ) , the d / D ratio in animals with
hypercapnia ( pCO2 = 69.9 mm Hg ) was increased by 11.7 % in the pial arteries and 7.9 % in the cortical arteries , indicating vasodilatation . -
pubmed
The pathogenesis of
ischaemic neuronal damage along the cerebral arterial boundary zones in
Papio anubis . -
pubmed
The pathogenesis of
ischaemic neuronal damage along the arterial boundary zones of the forebrain was investigated in 20 lightly anaesthetized , spontaneously breathing
baboons . -
pubmed
Additional occlusion of the left common carotid artery for 20 min had no effect on the EEG ( except for one
animal with a
cerebrovascular anomaly ) . -
pubmed
The brains of 3
animals were normal and in the 15 with
brain damage this was restricted in the cerebral cortex to the arterial boundary zones . -
pubmed
Calcification and crystallization in
bovine enamel . -
pubmed
Are
animal models suitable for the study of
ischemic heart disease ? -
pubmed
Of 11
patients with degenerative changes in the distal radio - ulnar joint on preoperative X - ray , 8 stated they were helped by the operation , while of 13 patients without any signs of
arthrosis in the distal radio - ulnar joint , only 4 experienced relief of their discomfort . -
pubmed
A total of 110
children , aged 0 - 15 years , were investigated for circulating megakaryocytes in cubital venous blood using the
saponin -
haemolysis leucoconcentration technique . -
pubmed
Excitatory movements and
hypertonus occurred in seven
patients during operation and in ten
patients in the early recovery phase . -
pubmed
The latter was significantly depressed in the
tumor - bearing
animals as compared to the corresponding saline - injected controls . -
pubmed
Event - related potentials ( ERPs ) to visual and somatosensory stimuli , generated during an oddball task , were obtained in a group of
autistic children and 3 control groups ( normal , attention - deficit , and
dyslectic children , respectively ) . -
pubmed
Research questions were whether ( a )
autistic children differ from other
children with respect to the processing of visual and/or somatosensory stimuli , as measured in the amplitude of the N1 , mismatch activity , and P3 , ( b ) autistic
children specifically have problems in the processing of distal ( visual ) stimuli , compared to the processing of proximal ( somatosensory ) stimuli , and ( c ) autistic
children have an atypical lateralization pattern of ERP activity . -
pubmed
BACKGROUND : We describe a recently observed set of autosomal dominant
GEMSS (
glaucoma ,
lens ectopia ,
microspherophakia ,
stiffness of the joints , and
shortness ) syndrome in a 47 - year - old
woman and her 23 - year - old son . -
pubmed
In addition ,
sclerosis of the skin , from which both
patients suffered , is investigated in detail . -
pubmed
The estimated
blood loss ( 873 + /- 484 ml ) and the preoperative hematocrit ( 33.4 % + /- 6.4 % ) in the women who did not receive transfusion were not significantly different from those of
patients who received packed red blood cells ( 854 + /- 576 ml and 30.0 % + /- 5.4 % , respectively ) . -
pubmed
Pelvic actinomycosis is a rare disorder caused by Gram - positive anaerobic bacteria
Actinomyces Israeli , and it is commonly associated with the prolonged use of IUD . -
pubmed
The ALL-1 gene , located on chromosome band 11q23 , is fused to a variety of other genes by reciprocal
chromosomal translocations present in 5 - 10 % of
human acute leukemias . -
pubmed
METHODS : Measurements of hemostatic function and metabolic and angiographic indicators of risk were included in a prospective cohort study of variables predictive of
reinfarction ,
cardiac death and major coronary events within 6 to 9 years in 108 unselected nondiabetic
men with a first
myocardial infarction before age 45 years . -
pubmed
RESULTS : During follow - up , 20
patients had
sudden cardiac death , and 53 had a major coronary event (
reinfarction ,
sudden cardiac death , bypass surgery or intervention by catheterization ) . -
pubmed
Subsequent
Bowen ' s disease occurred in eight
patients ( 11.3 % ) . -
pubmed
Twenty - six
patients ( 36.6 % ) had concurrent
skin cancers , either
basal cell carcinoma or
squamous cell carcinoma , or both . -
pubmed
By crossing the complex - glycan - deficient
strain of
A. - pubmed
Lysophosphatidylcholine accumulates in the coronary
sinus during pacing - induced
myocardial ischemia in
humans . -
pubmed
This amphiphile accelerates
Ca ++ flux leading to cell
injury in cultured cardiac myocytes , but it is not known whether
lysophosphatidylcholine accumulation is injurious to
human myocardium . -
pubmed
We conclude that
lysophosphatidylcholine accumulation is a marker of
myocardial ischemia in
humans . -
pubmed
In two consecutive studies , 80 subjects
human immunodeficiency virus (
HIV)-1 - seropositive ( 21 asymptomatic , 6 persistent generalized
lymphadenopathy , 13
AIDS - related complex , and 40
AIDS ) were examined for
oral lesions . -
pubmed
In the second study of 25 patients ,
HIV was detected in plasma of 56 % ( titers , 1/10 to & gt ; 1/1000 ) but not in diluted saliva supernatants , even in those with severe
periodontal disease . -
pubmed
Hence ,
infectious HIV and DNA was found at very low concentrations in 21 % and 28 % of
HIV - seropositive patients , respectively , at all stages of
HIV infection . -
pubmed
Assessment of the efficacy of an antibiotic drug used in
patients with various manifestations of
dermatoborreliosis is crucial . -
pubmed
It was intended to establish a constant parameter -- besides the clinical picture -- for assessing the efficacy of antibiotic treatment in patients with
dermatoborreliosis in terms of eradication of
Borrelia burgdorferi from the site of
infection . -
pubmed
burgdorferi - specific DNA was amplified by PCR in 23/36
erythema migrans patients ( 69 % ) , and in 5/7
acrodermatitis chronica atrophicans patients ( 71 % ) . -
pubmed
However ,
patients with
steatosis had serum mass concentrations of this enzyme significantly lower ( mean 2 - 3 fold ) than those measured in
cancer patients ( P & lt ; 0.05 ) or
cirrhotic patients ( P & lt ; 0.001 ) . -
pubmed
[
Superior sagittal sinus thrombosis in
children during the first year of life : clinical aspects , imaging and development ] . -
pubmed
PATIENTS : From 1988 to 1994 , 11
children had
cerebral venous thrombosis ( longitudinal
sinus ) in the first year of their life . -
pubmed
METHODS : Eighteen anaesthetized
dogs underwent progressive isovolaemic
haemodilution with either HES ( group 1 ) or UPBH ( group 2 ) to haematocrit target levels of 15 , 10 and & lt ; 5 % . -
pubmed
One
dog without
haemodilution figured as control
animal . -
pubmed
In contrast , HES - treated
animals showed severe histological changes of renal tubuli caused by isovolaemic
anaemia . -
pubmed
The target level of LDL -
cholesterol is less than 1.30 g / l in
patients with known
coronary heart disease . -
pubmed
Therefore these ,
patients with a
MGUS and
clinical deterioration despite conventional immunosuppressive treatment should undergo large - scale diagnostic check - up to make sure that the chance for an adequate chemotherapy is taken . -
pubmed
Mechanisms underlying stimulation of rapidly adapting receptors during
pulmonary air embolism in
dogs . -
pubmed
Clear cell "
sugar "
tumor of the lung : association with
lymphangioleiomyomatosis and multifocal micronodular
pneumocyte hyperplasia in a
patient with
tuberous sclerosis . -
pubmed
We report the unique association of a clear cell "
sugar "
tumor of the lung (
CCTL ) in a 32 - year - old
woman with
tuberous sclerosis (
TSC ) ,
lymphangioleiomyomatosis (
LAM ) , and
multifocal micronodular pneumocyte hyperplasia (
MMPH ) . -
pubmed
Early assessment of
patients with suspected acute
myocardial infarction by biochemical monitoring and neural network analysis . -
pubmed
Eighty - eight
patients admitted within 8 h after onset of
chest pain were included . -
pubmed
It gives documented good
patient satisfaction , range of motion ,
pain relief and relatively few serious complications . -
pubmed
In animal and
human models , left ventricular ( LV ) diastolic function has been observed to be highly sensitive to
myocardial ischemia . -
pubmed
Eight mongrel
dogs , in which were inserted a high - fidelity micromanometer LV catheter , coronary
sinus sampling catheter , and ultrasonic coronary artery flow probe , underwent intravenous
dobutamine infusion at escalating doses both before ( control protocol ) and after (
ischemia protocol ) creation of
left anterior descending coronary artery stenosis with a hydraulic cuff occluder adjusted to maintain resting coronary artery flow but attenuate reactive
hyperemia . -
pubmed
Immunophenotyping of
acute lymphoblastic leukemia in pediatric
patients by three - color flow cytometric analysis . -
pubmed
Stapled versus sutured gastrointestinal anastomoses in the
trauma patient . -
pubmed
To date , no study has evaluated the incidence of complications of stapled anastomoses in the
trauma patient . -
pubmed
CONCLUSION :
Anastomotic leaks seem to be associated with stapled bowel repairs compared with sutured anastomoses in the traumatically injured
patient . -
pubmed
On the first day of pregnancy ,
diabetes was induced by intravenous administration of
streptozotocin in half the
animals from the two diet groups . -
pubmed
Left ventricular hypertrophy (
LVH ) , a target - organ response to chronic pressure or
volume overload , is associated with its own independent risks of
death in
patients with
hypertension . -
pubmed
Preclinical and early
human studies of
calcium and
colon cancer prevention . -
pubmed
Normal
mouse and
rat strains as models for age - related
cataract and the effect of caloric restriction on its development . -
pubmed
The purpose of this study was to determine : ( 1 ) which of the commonly used
strains of laboratory
rats and
mice provide good models for
human age - related
cataract , and ( 2 ) whether long term caloric restriction , a regimen that prolongs both median and maximum life span in
rodents , would also delay the time of appearance of this age - related pathology . -
pubmed
These
strains were Brown Norway and Fischer 344
rats , and C57BL/6 , ( C57BL6 x DBA/2)F1 and ( C57BL/6 x C3H)F1
mice . -
pubmed
Various stages of
cataract were found in the great majority of these
animals in old age . -
pubmed
In both
rat strains and one
mouse strain the
cataracts occurred after mid - life , were most advanced late in life , and were similar in locations and appearance to those in
humans . -
pubmed
In the two
mouse strains in which some
cataracts appeared as early as 10 - 14 months of age , previously identified
genetic defects affecting the eye were probably involved in the early appearances . -
pubmed
Fulminant liver failure from acute
HCV superinfection in a patient with
HIV ,
HBV , and
HDV coinfections . -
pubmed
Developmental
toxicity of
1,6 - hexamethylene diisocyanate (
HDI ) in the
Sprague - Dawley rat . -
pubmed
Employing multichannel MEG we calculated local Lyapunov exponents ( ILE ) as a measure of the probability of state transitions in
patients with
mesiotemporal and extra - mesiotemporal focal epilepsy . -
pubmed
Altogether , 145
patients with operable invasive
breast cancer and clinically negative lymph nodes were studied . -
pubmed
The overall accuracy of
patients with
SNs resected was 98.4 % , and the false - negative rate was 4.4 % . -
pubmed
The introduction of magnetic resonance imaging ( MRI ) has greatly improved the evaluation of
patients with
scoliosis allowing assessment of any underlying
intraspinal abnormalities . -
pubmed
PURPOSE : To present a case report on a
patient with
keratouveitis after exposure to a tarantula . -
pubmed
CONCLUSION : Hairs from
pet tarantulas might penetrate deeply into the eye and give
keratouveitis . -
pubmed
We describe a
child with a disorder that is best described as
angiokeratoma of Mibelli . -
pubmed
The similarity of both the diffusion coefficients and permeability values obtained for a range of hydrophilic and lipophilic compounds in the two models indicates that the mucus layer secreted by the
human adenocarcinoma HT29 - MTX goblet cells does not constitute a diffusion barrier to such compounds . -
pubmed
Embryonic ventral mesencephalic grafts to the substantia nigra of
MPTP - treated
monkeys : feasibility relevant to multiple - target grafting as a therapy for
Parkinson ' s disease . -
pubmed
We experienced a 30 - year - old
man suffering from
TCRgammadelta T - cell leukemia with morphology compatible to
T - PLL with a postthymic phenotype . -
pubmed
We report on a young patient with
chronic cervical lymphadenopathy and serological and histological evidence for
infection with
Bartonella henselae and
Toxoplasma gondii . -
pubmed
Neuronal ceroid lipofuscinosis in Merino
sheep . -
pubmed
OBJECTIVE : To characterise
neuronal ceroid lipofuscinosis (
NCL ) in Merino
sheep . -
pubmed
PROCEDURE :
NCL cases were studied from a medium - wool Merino flock , the stud of origin of its replacement
rams , and an experimental flock established at the University of Sydney . -
pubmed
A homozygosity mapping approach localised the gene causing the disease in Merino
sheep to the chromosomal region ( OAR7q13 - 15 ) associated with
NCL in South Hampshire
sheep . -
pubmed
CONCLUSION :
NCL in Merino
sheep is a subunit c - storing disease , clinically and pathologically similar to
NCL in South Hampshire
sheep . -
pubmed
OBJECTIVE : To evaluate the frequency and location and to determine the long - term MR changes in
patients with
edema - like
bone marrow abnormalities after acute
knee trauma . -
pubmed
DESIGN AND
PATIENTS : A cohort of 176 consecutive
patients in a 29 month period with acute
injury of the knee joint was examined with MRI . -
pubmed
Forty - nine
patients with
bone marrow edema - like signal alteration on the initial MR examination were re - evaluated with MRI after a minimum of 2 years ( mean 44 months ) . -
pubmed
Fourteen allelic variants not described in clinical isolates so far were observed among 36 ( 10 % ) of 356 Brazilian
strains , including a new pattern for
Mycobacterium scrofulaceum ,
M. - pubmed
METHODS : A 7 - year - old
boy with a lateral orbital mass and
infratemporal fossa mass underwent computed tomography and surgical excision . -
pubmed
Use of serologic tests to predict resistance to
feline herpesvirus 1 ,
feline calicivirus , and feline
parvovirus infection in
cats . -
pubmed
Because most client - owned
cats had detectable serum antibodies suggestive of resistance to
infection , use of arbitrary booster vaccination intervals is likely to lead to unnecessary vaccination of some
cats . -
pubmed
OBJECTIVE : Transmyocardial laser revascularization is a new technique that improves symptoms in
patients with
refractory angina not amenable to conventional revascularization . -
pubmed
METHODS : Sixteen
patients ( 12
men and 4
women ; mean age , 60 + /- 8 years ) with
coronary artery disease were studied . -
pubmed
[
Poikllodermia atrophicans vascularis in
mycosis fungoldes with indication for treatment with radioactive
yttrium ( Y90 ) ] . -
pubmed
Cloacal prolapse in
ostrich chicks with
histomoniosis . -
pubmed
Researchers report findings on
HIV drug resistance , new
infections . -
pubmed
In this prospective , randomized , double - blind , controlled study we tested the hypothesis that auricular electroacupuncture ( EA ) relieves
pain more effectively than conventional manual auricular acupuncture ( CO ) in chronic
low back pain patients with insufficient
pain relief ( visual analogue scale [ VAS ] & gt ; or = 5 ) treated with standardized analgesic therapy . -
pubmed
Neuropathic pain in particular improved in
patients treated with EA . -
pubmed
IMPLICATIONS : Continuous electrical stimulation of auricular acupuncture points using the new point stimulation device P - stim significantly decreases
pain intensity and improves psychological well - being , activity , and sleep in
chronic low back pain patients . -
pubmed
Effectiveness of a school - based multicomponent program for the treatment of
children with
ADHD . -
pubmed
Fifty
children with
ADHD participated in the study . -
pubmed
Evaluation of hepatosplanchnic circulation and intestinal oxygenation in
dogs with a condition that mimicked
septic shock induced by continuous infusion of a low dose of lipopolysaccharide . -
pubmed
OBJECTIVE : To determine whether continuous infusion of a low dose of lipopolysaccharide ( LPS ) to induce a condition mimicking
septic shock in
dogs would affect systemic and hepatosplanchnic circulation and oxygenation . -
pubmed
However , in light of the fact that some regenerative capabilities of the endocrine pancreas have been documented and recent research has shown that
human ES cell lines can be derived in vitro , this review discusses whether it is practical or even possible to combine these lines of research to more effectively treat young
diabetic patients . -
pubmed
PURPOSE : We present a 30 - year experience with performing salvage surgery in
patients with persistent
prostate cancer ( PCA ) after definitive radiotherapy . -
pubmed
The charts of all 253
patients seen during a four - month period with a diagnosis of
hypertension were analyzed . -
pubmed
Here we describe approaches that can be used to study
cardiac toxicity in developing
zebrafish , focusing on examples where
zebrafish embryos have been especially useful in understanding the impact of specific toxicants on heart development and function . -
pubmed
The left 48
rats were randomly divided into 4 groups after ovariectomy : group A and B of
osteoporotic animal model with normal physiological saline , prevented and treated groups of
osteoporotic animal model with BBC . -
pubmed
These studies demonstrated , for the first time , the existence of a specialized carrier - mediated system for
riboflavin uptake in
human - derived
retinoblastoma cells . -
pubmed
Occupational contact
urticaria from
walnut associated with
hand eczema . -
pubmed
PURPOSE : To evaluate tear film quality by rose bengal staining and its stability by breakup time , relating with palpebral fissure height and
exophthalmos in
patients with
Graves ' ophthalmopathy . -
pubmed
METHODS : We studied 54 eyes of 27
patients with
Graves ' ophthalmopathy , either in the inflammatory or in the chronic phase of the disease . -
pubmed
This article describes our experience with laparoscopic procedures for
patients with Stage IV
colorectal cancer and compares their perioperative outcomes to a contemporaneous group of patients with clinically curable ( Stages I - III ) disease . -
pubmed
BACKGROUND : Twenty percent of
patients with
chronic hepatitis C evolve to
cirrhosis in 10 to 20 years . -
pubmed
PATIENTS AND METHODS : Retrospective study of 84 liver biopsies of
patients with
chronic infection with hepatitis C virus were studied . -
pubmed
We present the case of a
patient with
malignant glucagonoma treated with surgery and
octreotide , which manifested with
skin lesions . -
pubmed
Our previous work using the
Lewis Lung Carcinoma ( LLC ) model of
tumor bearing (
TB )- mice has shown several
tumor - induced immune suppressing effects to be present . -
pubmed
In this paper , we studied the potential of HS to decrease
tumor burden via in vivo treatment of
TB - mice . -
pubmed
On gross examination , HS treatment produced a decrease in
tumor surface
necrosis with a visible ( 2 + /- 1.8 % ) surface necrotic area in treated
mice as opposed to a ( 43 + /- 16 % ) surface
necrotic area in untreated
mice . -
pubmed
HS treatment decreased TB -
mice splenomegaly when comparing
mice spleen weights in treated ( 0.3 + /- 0.05 g ) vs. untreated ( 0.14 + /- 0.02 g ) groups . -
pubmed
DESIGN : Case series of
neonates with severe
PPHN ( defined as oxygenation index [ OI ] & gt;20 , failure of iNO therapy , and echocardiographic confirmation of
PPHN ) . -
pubmed
RESULTS : Nine
neonates at a mean gestation of 39.25 + /- 2.76 weeks ,
birth weight of 3668 + /- 649.1 g , and baseline OI of 28.1 + /- 5.9 received
milrinone treatment after a poor initial response to
iNO treatment . -
pubmed
Infants who received
milrinone did not develop systemic
hypotension ; in fact , there was a nonsignificant trend toward improved blood pressure . -
pubmed
Gender differences in lymphocyte populations , plasma HIV RNA levels , and
disease progression in a cohort of children born to women infected with
HIV . -
pubmed
Background A 75 - year - old
woman with
rheumatoid arthritis presented with a 4 - year history of
chorea to a hospital
movement disorder clinic . -
pubmed
Aseptic
peritonitis in a peritoneal dialysis
patient . -
pubmed
INTRODUCTION :
Patients who have repeatedly sterile peritoneal fluid cultures despite elevated peritoneal fluid white cell count should be evaluated for disorders other than usual
bacterial peritonitis . -
pubmed
CASE REPORT : A 25 - year - old male non -
diabetic patient in
PD started his complains with diffuse
abdominal pain with
spontaneous remissions and exacerbations ,
anorexia and
vomiting with 3 days evolution . -
pubmed
Y
chromosome deletions arise frequently in
human populations , where they cause sex reversal and
Turner syndrome and predispose individuals to
infertility and
germ cell cancer . -
pubmed
Subjects were 34
patients , 32
men and 2
women , with
squamous cell carcinoma of the oropharynx , with a median age of 63 years ( range , 47 to 72 year ) . -
pubmed
Samples comprised 8 diploid species of Coffea , 5 individuals of
tetraploid C. - pubmed
METHODS : This was a nonrandomized observational prospective trial over 9 months , with data collection on 28 eyes of 26 consecutive
patients who underwent phacovitrectomy , internal limiting membrane peel , and intraocular gas tamponade ( C2F6 ) for stage 2 , 3 , and 4
macular holes . -
pubmed
The combination of phacoemulsification , pars plana vitrectomy , internal limiting membrane , and gas tamponade in
macular hole surgery reduces the difficulty of posturing in elderly
patients . -
pubmed
This technique saves the
patient from exposure to a second intraocular intervention to remove a
cataract which will commonly develop after vitrectomy and gas tamponade alone . -
pubmed
Like the
mammalian nervous system , the
Lymnaea nervous system responds to
injury with recruitment and activation of endoneurial phagocytes ( i.e. -
pubmed
PURPOSE : To evaluate the effect of the size of
zona pellucida opening by laser assisted hatching for frozen cleaved embryo that were thawed after both fresh and frozen cleaved embryo transfer cycles failed and were cultured to blastocyst after thawing in
patients with multiple implantation failures . -
pubmed
MATERIALS AND METHODS : Of 101 consecutive procedures ( October 2003 to June 2006 ) , 30
patients declined to perform assisted hatching and were selected as control group , 40
patients had 40 microm opening of the
zona ( October 2003 to January 2005 ) , 31
patients had 50 % of the
zona opening ( February 2005 to June 2006 ) . -
pubmed
Three
patients experienced a full - thickness epithelial breakthrough and the fourth , a
flap tear . -
pubmed
The
patient who experienced the
flap tear was unable to have laser in situ keratomileusis successfully . -
pubmed
The flap complications did not result in a decreased best corrected visual acuity in any
patient but may have resulted in epithelial ingrowth in one and a
corneal scar and microstriae in another . -
pubmed
CONCLUSIONS : The results indicate that sounds from
pulse oximeters pose a potential risk of not only sleep disturbance and annoyance but also
hearing loss , and that these sounds are unnatural for
human auditory perception . -
pubmed
Using integrative genomics to elucidate genetic resistance to
Marek ' s disease in
chickens . -
pubmed
This briefly summarizes some of our efforts to apply several genomic and functional genomics approaches to identify genes and pathways that confer genetic resistance to
Marek ' s disease (
MD ) , a herpesvirus - induced
T cell lymphoma of
chickens . -
pubmed
By utilizing the " top - down " approach of QTL to identify genomics regions , and integrating it with " bottom - up " approaches of transcript profiling and
Marek ' s disease virus (
MDV)-
chicken protein - protein interactions , three genes that confer resistance to
MD are revealed , plus a number of other positional candidate genes of high confidence . -
pubmed
Of 12 infants ( 3
boys and 9 girls ) , 9 have a family history of
DM . -
pubmed
Studies on
hypertension ; mechanism of the fall in arterial pressure produced by high spinal anesthesia in
patients with essential
hypertension . -
pubmed
Further determination of
recurrence and progression marker will contribute to establish better treatments for the individual
patient . -
pubmed
OBJECTIVE : Cytomegalovirus (
CMV ) is an important pathogen in healthy neonates and individuals with
human immunodeficiency virus (
HIV-1 ) . -
pubmed
The objective of this study was to determine whether the detection of
CMV DNA (
CMV DNAemia ) in maternal plasma was associated with mortality in
HIV-1 - infected women or their infants . -
pubmed
Additionally ,
HIV-1 - infected infants born to
CMV DNAemic women had a four - fold increased risk of mortality during 24 months of follow - up . -
pubmed
CONCLUSION : Maternal plasma
CMV DNAemia identified a subgroup of Kenyan women and infants at high risk for
death in the 2 years following delivery . -
pubmed
Anatomical architecture and responses to
acidosis of a novel respiratory neuron group in the high cervical spinal cord ( HCRG ) of the neonatal
rat . -
pubmed
Neuroprotective effects of
probenecid in a transgenic
animal model of
Huntington ' s disease . -
pubmed
In this study , we examined the effects of
probenecid on the survival , behaviour and immunohistochemical changes in the N171 - 82Q transgenic
mouse model of
HD . -
pubmed
However , the time resolution in
STEMI patients is hampered by the rather vague time point ' onset of
pain ' . -
pubmed
We therefore sought to utilize a time - wise more reliable model of
human myocardial necrosis : percutaneous transluminal septal myocardial ablation ( PTSMA ) of
hypertrophic obstructive cardiomyopathy (
HOCM ) . -
pubmed
METHODS : Blood samples were obtained from 8
patients with
HOCM just prior to initiation of PTSMA and up to 50 h following the procedure . -
pubmed
BACKGROUND : The rationale for screening populations at risk for
hepatitis C virus infection (
HCV ) includes the possibility of altering risk behaviors that impact
disease progression and transmission . -
pubmed
they were documented
HCV seronegative at study onset and subsequently seroconverted during the follow - up period , with
infection confirmed by
HCV RNA testing . -
pubmed
PATIENT REPORT : A 68 - year - old
man with invasive
bladder cancer disseminated in penile shaft and the pelvic lymph nodes is presented . -
pubmed
Inadequate antigen presentation and/or suboptimal immunogenicity are considered major causes in the failure of
human immunodeficiency vaccine to adequately protect against wild - type virus . -
pubmed
Cardiovascular changes in spontaneously
hypertensive rats are improved by chronic treatment with
zofenopril . -
pubmed
BACKGROUND AND PURPOSE : The aim of this study was to investigate the effect of chronic treatment with antihypertensive and non - antihypertensive doses of
zofenopril on cardiovascular changes in spontaneously
hypertensive rats ( SHR ) . -
pubmed
OBJECTIVE : To analyze the results of pre - operative local therapy for
hepatocellular carcinoma in
patients who were subjected to liver transplantation . -
pubmed
METHODS : Cadaveric and living - related liver transplants done in cirrotic
patients with
hepatocellular carcinoma within the Milan criteria were included . -
pubmed
CONCLUSION : Local therapy for
hepatocellular carcinoma with percutaneous
ethanol injection and transarterial chemoembolization partially controlled
tumor evolution considering the Milan criteria in
patients waiting for liver transplantation . -
pubmed
Susceptibility of carbapenemase - producing
strains of
Klebsiella pneumoniae and
Escherichia coli to the direct antibacterial activity of
NAB739 and to the synergistic activity of
NAB7061 with
rifampicin and
clarithromycin . -
pubmed
OBJECTIVES : To determine the susceptibility of carbapenemase - producing
strains of
Klebsiella pneumoniae and
Escherichia coli to the direct antibacterial activity of
NAB739 and to the synergistic activity of NAB7061 with
rifampicin and
clarithromycin . -
pubmed
RESULTS : The MICs of NAB739 for all nine
polymyxin - susceptible , carbapenemase - producing
strains were identical or very close to those determined for
E. - pubmed
The
polymyxin - resistant
strain K. - pubmed
In addition , NAB7061 has notable synergism with
rifampicin and
clarithromycin against all the carbapenemase - producing
strains tested , including the
polymyxin - resistant
K. - pubmed
For allogeneic stem cell transplant , the conditioning chemotherapy regimen comprised
busulfan ,
cyclophosphamide , and
antithymocyte globulin for
thalassemic patients ;
busulfan and
cyclophosphamide for
leukemia patients ; and
cyclophosphamide and
antithymocyte globulin for
patients with
aplastic anemia . -
pubmed
RESULTS : During this period , 155
B - thalassemia major
patients ( mean age , 9.5 years ; range , 2 - 20 years ) underwent allogeneic marrow transplant . -
pubmed
Of 155
patients with a diagnosis of
thalassemia major , 112 are alive ( 72 % ) with full engraftment after a median follow - up of about 8.1 years ( range , 12 - 184 months ) . -
pubmed
During this time , 127
leukemia patients including
acute myelogenous leukemia ( n=68 ) ,
acute lymphoblastic leukemia ( n=30 ) and
chronic myelogenous leukemia ( n=29 ) , received allogeneic stem cell transplant . -
pubmed
In
patients with
B - thalassemia major hematopoietic stem cell transplant seems to be the treatment of choice , because it leads to a cure in all classes ( Lucarelli risk group , I - III ) . -
pubmed
Murine spleen lymphocytes apoptosis in the experimental model of
staphylococcal intravaginal infection . -
pubmed
The results of research on changes in the level of apoptosis among the spleen cells during the development of intravaginal
staphylococcal infection in experimental models of different genetic
mice lines are given in the paper . -
pubmed
Chronic osteomyelitis complicating war compound
fractures ; an evaluation of 125
patients treated by early secondary closure . -
pubmed
Epileptogenic glioma in a 4 - year - old
child : a case report . -
pubmed
This 4 - year - old
girl presented with a 1 - year history of complex partial
seizure . -
pubmed
This is apparent in
depressive patients with
BPD . -
pubmed
It also improves sleep - wake patterns and
behavioural disorders in hospitalized
patients with
Alzheimer ' s disease . -
pubmed
The treatment of comorbid
depressive disorder and
borderline personality disorder (
BPD ) is usually reported to be less successful than the treatment of
patients without
personality disorder . -
pubmed
RESULTS : Five
patients discontinued from the trial due to oral administration of
Iressa after
disease progression or other reasons , and 116
patients were evaluable for clinical efficacy with 63 in the treatment group and 53 in the control group . -
pubmed
CONCLUSIONS : Chinese herbal medicine combined with chemotherapy showed favorable effect in improving quality of life and prolonging survival time on
patients with advanced
NSCLC . -
pubmed
The data acquired in this pilot study validate
BoHV-4 - based vector as a safe and effective heterologous antigen carrier / producer for the formulation of enhanced recombinant immunogens for the vaccination against
lethal bluetongue . -
pubmed
We report a case of a
patient with
chronic kidney disease likely due to lead
nephropathy . -
pubmed
Retrospective study on the effect of tight
glucose control in
postoperative sepsis patients using an artificial pancreas . -
pubmed
The present study was undertaken to examine whether the use of an artificial pancreas to achieve TGC would be possible in postoperative
patients with
sepsis . -
pubmed
No
hypoglycemia associated with the artificial pancreas was seen in any of the
patients . -
pubmed
Further data collection from a larger number of cases would be expected to allow a precise assessment of TGC as a potentially beneficial intervention in
sepsis patients . -
pubmed
Avotermin for
scar improvement following
scar revision surgery : a randomized , double - blind , within -
patient , placebo - controlled , phase II clinical trial . -
pubmed
METHODS : Sixty
patients ( 35
men and 25
women ; age , 19 to 78 years ; 53
Caucasians ;
scar length , 5 to 21 cm ) received intradermal
avotermin ( 200 ng/100 mul / linear cm
wound margin ) and placebo to outer
wound segments immediately after , and again 24 hours after , complete ( group 1 ) or staged ( group 2 )
scar revision surgery . -
pubmed
A within -
patient design was chosen to control for interindividual factors that affect
scarring . -
pubmed
This method could be useful for quantitative gene expression analysis in blood vessels from
tumors of
patients that have been treated with antiangiogenic drugs , allowing for validation of the effect of drug on the expected targets . -
pubmed
Serum levels of
25 - hydroxyvitamin D and survival in Norwegian
patients with
cancer of breast , colon , lung , and
lymphoma : a population - based study . -
pubmed
METHODS : The study population was 658
patients with
cancers of the breast ( n = 251 ) , colon ( n = 52 ) , lung ( n = 210 ) , and
lymphoma ( n = 145 ) , obtained from JANUS , a population - based serum bank in Norway . -
pubmed
A total of 149
patients with
multiple myeloma (
MM ) who received allogeneic hematopoietic stem cell transplantation ( allo - HCT ) with myeloablative ( MAC ; n = 38 ) or reduced - intensity conditioning ( RIC ; n = 110 ) regimens at MD Anderson Cancer Center were evaluated . -
pubmed
Median age of
MM patients was 50 ( 28 - 70 ) years with a followup time of 28.5 ( 3 - 164 ) months . -
pubmed
We observe that TRM has decreased with the use of RIC regimens , and long - term disease control can be expected in a subset of
MM patients undergoing allo - HCT . -
pubmed
AIMS : To determine ( 1 ) the accuracy of positron emission tomography - computed tomography in the diagnosis of
head and neck cancer , ( 2 ) the learning curve involved , and ( 3 ) whether its use alters
patient management . -
pubmed
MATERIALS AND METHODS : A retrospective study including 80
patients with
head and neck cancer who underwent positron emission tomography - computed tomography image fusion at Blackpool Victoria Hospital . -
pubmed
RESULTS : Fifty - three
patients underwent positron emission tomography - computed tomography for staging ( 32 for detection of a primary
tumour and 21 for detection of distant
metastasis ) and 27 for detection of loco - regional
recurrence . -
pubmed
Eighteen
patients had their
tumour stage and management modified as a result of this method of imaging . -
pubmed
METHODS : In this retrospective cross sectional study , 426
patients with
cholecystitis who were admitted to Hamadan hospitals including Ekbatan , Tamin Ejtamaiee , Mobasher , Boali and Artesh and were subjected to laparoscopic cholecystectomy from 1997 to 2005 were evaluated . -
pubmed
We included
individuals with unilateral
vestibular nerve schwannomas confirmed by imaging . -
pubmed
RESULTS : A total of 44
patients with
vestibular nerve schwannomas and 104 controls participated in the study . -
pubmed
In the JT - group , relaparotomy was performed in three
patients ( 6 % ) because of JT - leakage or
strangulation leading to
death in one patient ( 2 % ) . -
pubmed
Protective effect of
omega-3 polyunsaturated fatty acids (
PUFAs ) on
sodium nitroprusside - induced
nephrotoxicity and oxidative damage in
rat kidney . -
pubmed
The results of the present study suggest that
omega-3 PUFA - enriched FO and FXO from
seafoods and
plant sources , respectively , are similarly effective in reducing
SNP - induced
nephrotoxicity and oxidative damage . -
pubmed
We examined frozen samples from the cerebellum and temporal cortex ( Brodmann area 22 ( BA22 ) ) from
individuals with
autism and unaffected controls ( n=15 and n=12 per group , respectively ) . -
pubmed
Batrachochytrium dendrobatidis ( Bd ) is the causative agent of
chytridiomycosis , a
fungal skin disease in amphibians and driver of worldwide amphibian declines . -
pubmed
Ninety
neuropathic diabetic foot
patients were divided into two groups : group B [ those without
CAD ( n=45 ) ] and group C [ those with higher risk of
CAD ( n=45 ) ] . -
pubmed
We reveal that exposure - based perceptual learning is more efficient in a
human model of
excitotoxic neurodegeneration than in healthy participants . -
pubmed
Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in
mouse fetal Leydig cells but permits normal genital and reproductive development . -
pubmed
These findings imply that
Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in
mouse fetal Leydig cells but permits normal genital and reproductive development . -
pubmed
Two entry inhibitors are currently approved for the treatment of
HIV - infected patients . -
pubmed
This review covers the entry inhibitors and their use in the treatment of
HIV - infected patients . -
pubmed
More than half of the
patients with high - risk
neuroblastoma (
NB ) will relapse despite intensive multimodal therapy , with an additional 10 % to 20 % refractory to induction chemotherapy . -
pubmed
Management of these
patients is challenging , given disease heterogeneity , resistance , and
organ toxicity including poor hematological reserve . -
pubmed
Immunotherapy with anti - GD2 has recently been incorporated into upfront therapy , but its role in the
relapse setting remains uncertain , especially for
patients with bulky disease . -
pubmed
Prevalence of
hemostatic disorders in
adolescents with
abnormal uterine bleeding . -
pubmed
STUDY OBJECTIVE : To evaluate the incidence of
hemostatic disorders in a population of
adolescents with various patterns of
abnormal uterine bleeding (
AUB ) . -
pubmed
PARTICIPANTS : One hundred thirteen
adolescents with
AUB ; mean age at menarche and mean age at the onset of symptoms 12 + - 1.2 years and 13.5 + - 2.8 years , respectively . -
pubmed
All
patients were screened for
hemostatic disorders with laboratory testing . -
pubmed
RESULTS : One hundred thirteen
adolescents with
AUB were identified . -
pubmed
CONCLUSION :
AUB in
adolescents is frequently associated with an underlying
disorder of hemostasis , most commonly a
platelet function disorder . -
pubmed
The results highlight the importance of screening for
coagulation disorders in
adolescents with
AUB , independently from the gynecologic age at onset . -
pubmed
MATERIALS AND METHODS : Fifty - three consecutive gastric
adenocarcinoma patients who underwent gastric resection ( Chung - Ang University Hospital , Seoul , Korea ) were included . -
pubmed
Cytotoxicity and gene expression profiling of
polyhexamethylene guanidine hydrochloride in
human alveolar
A549 cells . -
pubmed
In Korea ,
lung disease of
children and pregnant women associated with humidifier disinfectant use has become a major concern . -
pubmed
This study was done to elucidate the putative
cytotoxic effect of
PHMG and the
PHMG - mediated altered gene expression in
human alveolar epithelial
A549 cells in vitro . -
pubmed
METHODS : The authors retrospectively reviewed the medical records of 47 consecutive
patients with
CSA in whom the presence / absence of the pyramidal tract sign was noted . -
pubmed
Although this species is increasingly relevant to public health due its ability to successfully colonize both urban and rural habitats , favoring the dispersion of
viral infections , little is known about its biochemical traits , with all assumptions made based on studies of
A. - pubmed
THIS LITERATURE REVIEW HAS THE FOLLOWING OBJECTIVES : to define selection criteria for
patients who are candidates for focal therapy , to assess the current situation and results of the different therapeutic options , and to define procedures in cases of
recurrence and for follow - ups . -
pubmed
INTRODUCTION : Specialised care of
patients in advanced stages of
chronic kidney disease (
CKD ) is associated with better survival in dialysis , but it is not known which treatments specifically favour this outcome . -
pubmed
MATERIAL AND METHOD : Cohort , prospective observational study of 591
patients who started dialysis ( 491 haemodialysis and 100 peritoneal dialysis ) , who had previously been monitored in the
CKD clinic . -
pubmed
Single - institution Experience of SBRT for Lung Metastases in
Sarcoma Patients . -
pubmed
OBJECTIVES : Lung metastasectomy is regarded as the standard procedure for improving the prognosis of
patients with
metastatic sarcoma . -
pubmed
MATERIALS AND METHODS : Twenty - two
patients with metastatic
sarcoma to lung were treated by SBRT . -
pubmed
CONCLUSION : SBRT is an effective tool that might be used as an alternative to operative treatment of lung
metastases in
sarcoma patients . -
pubmed
Host immunity to
Clostridium difficile PCR ribotype 017
strains . -
pubmed
Clostridium difficile is an important nosocomial pathogen and the leading cause of
antibiotic - associated diarrhea . -
pubmed
METHODS : This prospective physiological study was performed in a university hospital 's paediatric intensive care unit and included 11
children ( aged 35.2 + - 23 days ) with
respiratory syncytial virus bronchiolitis with failure of nCPAP . -
pubmed
METHODS : This double - blind , placebo - controlled , randomized clinical trial included 85
participants with clinically definite
MS , 45 assigned to the treatment group and 40 to the placebo - control group . -
pubmed
All
patients had
Fuchs ' endothelial dystrophy and had previously received hydrophilic acrylic IOL models . -
pubmed
A
man in his 50s was admitted to our hospital for treatment of
hematemesis . -
pubmed
RESULTS : We documented 780 admitted
patients , mean age 70.43 years , 31 % with
heart disease , 29 %
COPD , 26 %
diabetes mellitus , 15 % prior antibiotic therapy and solid
neoplasm . -
pubmed
METHODS : For this study we retrospectively reviewed data from 193
patients who experienced drug
hypersensitivity reactions during general anaesthesia . -
pubmed
Seven
PCA patients , 6
TAD patients and 5 controls underwent neuropsychological assessment , MRI scan ,
11C - PIB PET scan and
18F - FDG PET scan . -
pubmed
And PCA
patients showed more severe posterior
atrophy and less severe
left medial temporal lobe atrophy compared with TAD
patients . -
pubmed
Our study thus provides a preliminary view of
PCA in Chinese
patients . -
pubmed
, rotavirus ,
porcine transmissible gastroenteritis virus , and
porcine epidemic diarrhea virus . -
pubmed
PRESENTATION OF CASE : We report a 4.5 year old female
patient who had
upper airway obstruction due to a fragmented and migrated tracheostomy tube . -
pubmed
The effects of an Ayurvedic medicinal toothpaste on clinical , microbiological and oral hygiene parameters in
patients with
chronic gingivitis : a double - blind , randomised , placebo - controlled , parallel allocation clinical trial . -
pubmed
OBJECTIVES : To study the efficacy of an Ayurvedic toothpaste containing these herbs in
patients with
chronic gingivitis . -
pubmed
CONCLUSIONS : This study provides robust evidence of the beneficial antiplaque and antigingivitis effects of the test herbal toothpaste Sudantha on
patients with
chronic gingivitis . -
pubmed
PURPOSE OF REVIEW : An increasing number of
patients are placed on extracorporeal membrane oxygenation ( ECMO ) for
respiratory or cardiac failure . -
pubmed
PURPOSE : About one - third of
individuals with
focal epilepsy continue to have
seizures despite optimal medical management . -
pubmed
Animals that received these perineural local anesthetics ( LAs ) injections showed increased severity of
injury compared to the control group . -
pubmed
Etiology search included testing for
hepatitis B virus (
HBV ) ,
hepatitis C virus (
HCV ) ,
autoimmune hepatitis ,
primary biliary cirrhosis ,
Wilson ' s disease and
hereditary hemocromatosis . -
pubmed
BACKGROUND :
Parkinson ' s disease (
PD ) is a progressive
neurodegenerative disorder of the central nervous system , observed in
patients aged older than 50 years . -
pubmed
Moreover , in view of the lack of evidence - based recommendations regarding the pharmacotherapy of
arterial hypertension in
PD patients , we propose effective and safe therapeutic algorithms for these two coexisting conditions . -
pubmed
Three hundred preterm
neonates with hemodynamically significant
PDA ( hs - PDA ) admitted at our neonatal intensive care unit were enrolled in the study . -
pubmed
CONCLUSION :
Paracetamol is as effective as
indomethacin and
ibuprofen in closure of
PDA in preterm
neonates and has less side effects mainly on renal function , platelet count , and GIT
bleeding . -
pubmed
Anaphylaxis to hidden
potato allergens in a
peach and egg
allergic boy . -
pubmed
Sweets are frequently implicated in
allergic reactions in children with
cow 's milk ,
egg ,
nuts or
fruits allergy , and they are the most relevant foods investigated as responsible allergens . -
pubmed
We report an
anaphylactic reaction to
candies in an egg and
peach allergic boy . -
pubmed
RESULTS :
Uterine papillary serous carcinoma : 5432
women with
UPSC were identified . -
pubmed
Uterine clear cell carcinoma : 2516
women with
UCC were identified . -
pubmed
Postural Control in
Children with
Dyslexia : Effects of Emotional Stimuli in a Dual - Task Environment . -
pubmed
Twenty - two
children with
dyslexia and twenty - two aged - matched children without
dyslexia participated in the study . -
pubmed
CASE DESCRIPTION : We report a lumbar 3 - 4 lesion causing
cauda equina compression in a 57 - year - old
man who presented with a 3 - month history of
low back pain and bilateral
sciatica , intermittent
urinary incontinence , and
erectile dysfunction . -
pubmed
The study includes seventeen
PD patients and sixteen age - matched controls . -
pubmed
Population pharmacokinetics of
lamotrigine co - administered with
valproic acid in Chinese
epileptic children using nonlinear mixed effects modeling . -
pubmed
METHODS : A total of 182
epileptic children who were treated with
LTG as monotherapy or as part of combination therapy were included in this study as the model group , and 61
patients were included as the validation group . -
pubmed
Background Kyphoplasty has been demonstrated to be minimally invasive and effective in treating
osteoporotic vertebral fracture patients with
back pain over the level of the fractured vertebrae . -
pubmed
Rare studies have reported on
thoracolumbar vertebral fracture patients presenting with
distal lumbosacral pain (
DLP ) . -
pubmed
Purpose To evaluate the therapeutic efficacy of kyphoplasty in treating
osteoporotic thoracolumbar vertebral fracture (
OTVF )
patients with
DLP and assess the clinical significance of focal
tenderness to palpation in these
patients . -
pubmed
Material and Methods Thirty - two
OTVF patients who only complained of
DLP were treated by kyphoplasty . -
pubmed
In addition , we compared the therapeutic efficacy of kyphoplasty in
patients with and without focal
tenderness to palpation . -
pubmed
Conclusion The possibility of
thoracolumbar vertebral fractures in elderly
patients complaining of
DLP should not be neglected . -
pubmed
Kyphoplasty presents a superior benefit in treating
OTVF patients with
DLP . -
pubmed
The absence of focal
tenderness does not influence the clinical efficacy in these
patients . -
pubmed
Children aged 2 to 18 years old who presented with acute
abdominal pain suggesting
appendicitis were included . -
pubmed
Amrubicin monotherapy for elderly
patients with relapsed
extensive - disease small - cell lung cancer : A retrospective study . -
pubmed
However , the efficacy of AMR in elderly
patients with relapsed
SCLC has not been sufficiently evaluated . -
pubmed
METHODS : The medical records of elderly
patients with relapsed
SCLC who received AMR as second - line chemotherapy were retrospectively reviewed , and their treatment outcomes were evaluated . -
pubmed
RESULTS : Thirty - one
patients with a median age of 72 years ( 22
patients with sensitive
relapse and 9 with refractory
relapse ) were analyzed . -
pubmed
The PFS ( 6.2 vs. 3.2 months ; P = 0.002 ) and OS ( 14.8 vs. 5.7 months ; P = 0.004 ) were significantly longer in
patients with sensitive
relapse than those with refractory
relapse . -
pubmed
The frequency of grade 3 or higher
neutropenia was high ( n = 18 , 58 % ) , while
febrile neutropenia was only observed in five
patients ( 16 % ) . -
pubmed
CONCLUSION :
AMR may be a feasible and effective regimen for elderly
patients with relapsed
SCLC . -
pubmed
RESULTS : We identified 75,666
patients treated for
urethral stricture disease , with 420 and 367 undergoing anterior and posterior urethroplasty , respectively . -
pubmed
This study suggests that the hsa_circ_0044235 in peripheral blood may be a potential biomarker of
patients with
RA . -
pubmed
Antiemetic use of
olanzapine in
patients with advanced
cancer : results from an open - label multicenter study . -
pubmed
The drug has a mean half - life of 30 h , which allows for a single daily administration and is therefore of interest in
patients with advanced
cancer suffering from
nausea . -
pubmed
OBJECTIVES : To investigate the antiemetic effect and tolerability of
olanzapine in
patients with advanced
cancer not receiving chemotherapy or irradiation . -
pubmed
METHODS :
Patients with advanced
cancer ( no curable treatment options ) with at least " moderate "
nausea and/or one
emetic episode within the last 24 h were included if they had not received chemotherapy or irradiation ( last 2 weeks ) and had no reversible causes of
nausea /
vomiting . -
pubmed
The primary efficacy parameter was
nausea after 24 h. RESULTS : Forty
patients from four
centers were included and all evaluable after 24 h. Thirty - six
patients experienced some degree of improvement . -
pubmed
Five
patients were withdrawn from the study primarily due to progression of
malignant disease or per
patient 's request . -
pubmed
CONCLUSIONS :
Olanzapine appears effective and tolerable as an antiemetic in
patients with advanced
cancer . -
pubmed
Of the 1049
patients who received stereotactic radiation therapy for
brain metastases , only 2 % had adjuvant whole brain radiation therapy , and this decreased from 4 % in 2013 to 0.7 % in 2017 ( P = .02 ) . -
pubmed
Emerging evidences indicate that
hepatitis B virus ( HBV ) infection is associated with
non - Hodgkin lymphoma (
NHL ) , but the mechanisms of
HBV - induction lymphomagenesis remain unclear . -
pubmed
Increased risk of
head injury in pediatric
patients with
attention deficit hyperactivity disorder . -
pubmed
In the writhing test , both hybrids showed significant an antinociceptive effect in
mice , while neither of them triggered the development of tolerance , nor did they produce
constipation . -
pubmed
Background : This study aims to evaluate the outcomes of sublobar resections in
patients with early - stage
non - small cell lung cancer and to investigate the factors affecting survival . -
pubmed
Methods : Medical files of a total of 63
patients ( 52
males , 11
females ; mean age 64 years ; range , 39 to 81 years ) who underwent sublobar resection for suspected or known early - stage
non - small cell lung cancer between January 2001 and August 2013 were retrospectively reviewed . -
pubmed
Data including demographic characteristics of the
patients , comorbid conditions , smoking status ,
surgical margin , visceral pleura invasion , distance from
surgical margin to
tumor ,
tumor size , pathological N status , cell type ,
tumor localization , and
recurrences were recorded . -
pubmed
Effects of Antipsychotic Medication on Brain Structure in
Patients With
Major Depressive Disorder and Psychotic Features : Neuroimaging Findings in the Context of a Randomized Placebo - Controlled Clinical Trial . -
pubmed
Importance : Prescriptions for antipsychotic medications continue to increase across many
brain disorders , including off - label use in
children and elderly individuals . -
pubmed
All
participants had major
depressive disorder with
psychotic features (
psychotic depression ) and were prescribed
olanzapine and
sertraline for a period of 12 to 20 weeks , which included 8 weeks of remission of
psychosis and remission / near remission of
depression . -
pubmed
BACKGROUND : In Canada , although the incidence of smoking - related
oral cavity cancers has decreased ,
oropharyngeal cancers associated with
human papilloma virus (
HPV ) are on the rise . -
pubmed
Hematopoietic stem cells are used in transplantations for
patients with
hematologic malignancies . -
pubmed
Assessment of Thymic Output Dynamics After in utero
Infection of
Mice With
Coxsackievirus B4 . -
pubmed
We recently documented
coxsackievirus B4 ( CV - B4 ) infection of Swiss albino
mouse thymus in the course of in utero transmission . -
pubmed
Derivation and validation of a clinical prediction model for assessing the risk of lower extremity amputation in
patients with
type 2 diabetes . -
pubmed
RESULTS : A total of 504
patients developed
LEA at an average follow - up of 7.4 years . -
pubmed
Poor glycemic control ,
glucose variation , comorbidities , and medication use were identified as predictive factors for
LEA in
patients with
type 2 diabetes . -
pubmed
Since the outbreak of
coronavirus disease (
COVID-19 ) that was discovered in 2019 in Wuhan , China , no standard therapy guideline has been set despite the severity of
severe acute respiratory syndrome coronavirus 2 (
SARS - CoV-2 ) and its high infectivity . -
pubmed
The Cellular basis of the
loss of smell in 2019 -
nCoV - infected individuals . -
pubmed
The identity of the cell lineages that underpin the
infection - associated loss of olfaction could be critical for the clinical management of 2019 -
nCoV - infected individuals . -
pubmed
We studied if
anosmia in 2019 -
nCoV - infected individuals can be explained by the expression patterns associated with these host - specific moieties across the known olfactory epithelial cell types , identified from a recently published single - cell expression study . -
pubmed
We used WGS data to investigate the genetic diversity of clinical isolates of the bacterial pathogen
Elizabethkingia anophelis to query the existence of a single -
strain outbreak in Ontario , Canada . -
pubmed
From the roots to the stem : unveiling pear root colonization and
infection pathways by
Erwinia amylovora . -
pubmed
Plant
infections after soil irrigation with
E. - pubmed
Overall , our findings revealed , for the first time , common
root infection patterns between
E. - pubmed
Causes of readmission include
pseudomeningocele ( 8
patients ; 38 % ) ,
CSF leakage combined with poor incision healing ( 6
patients ; 29 % ) ,
wound dehiscence ( 2 patient ; 9 % ) ,
surgical site infection ( 2
patients ; 9 % ) ,
spinal epidural hematoma ( 1 patient ; 5 % ) , inadequate original surgical decompression ( 2
patients ; 9 % ) . -
pubmed
When compared to the non - readmitted
patients , diagnosis of
OPLL + OFL , circumferential decompression ,
dural injury , long hospital stay were more to be seen in readmitted
patients . -
pubmed
Four cases , given in some detail , illustrate the effort to compare scalp EEGs taken before surgery for intractable
seizures with those recorded some years postoperatively , and to relate these , together with the computer analyses of
seizure activity recorded in depth , with the pathology found in the removed tissue and , importantly , with the postoperative clinical state of the
patient . -
pubmed
Inorganic
phosphate inhibited the biosynthesis of the
macrolide antibiotic
turimycin in different
strains of
Streptomyces hygroscopicus . -
pubmed
The test was done in 10
horses and 15
ponies with naturally acquired
parasitic infections . -
pubmed
Ultrastructural studies were performed on portions of the operatively resected right atrium from six
patients with a
ventricular septal defect and six
patients with an
endocardial cushion defect . -
pubmed
The six
patients with a
ventricular septal defect had normal right atrial mean pressure and no evidence of right atrial volume overload . -
pubmed
The six
patients with an
endocardial cushion defect had elevated right atrial mean pressure and evidence of right atrial volume overload . -
pubmed
No adverse effects were observed in the
dogs and
rats other than
alopecia in
rats at the dose levels of 5.0 and 11.8 ppm . -
pubmed
Renal failure developed in 20
patients following blunt civilian
trauma . -
pubmed
[ Effect of
obsidan on the course of experimental
myocardial infarct with
arrhythmias in
rabbits ] . -
pubmed
Experimental
myocardial infarction (
EMI ) was reproduced in 35 of 40
rabbits operated upon . -
pubmed
Reintroduction of
obsidan to
rabbits with EMI complicated by
sinus bradycardia and
ventricular extrasystole is prognostically dangerous (
ventricular extrasystole relapses and its transformation into
ventricular tachycardia is possible ) . -
pubmed
Two
patients are described who presented with clinically solitary
thyroid nodules which were found to be due to metastatic disease from the kidney and colon respectively . -
pubmed
Human red cell and plasma lipids are determined in alcoholic
patients with various forms of
liver diseases including
steatosis ,
cirrhosis and
hepatitis . -
pubmed
The incidence of
hyperparathyroidism was not influenced by the age of the
patient , but it increased with duration of dialysis . -
pubmed
Of 16
patients treated by subtotal parathyroidectomy , all had large
hyperplastic parathyroid glands . -
pubmed
All of the
patients who were observed for longer than six months had progressive improvement in the
bone disease . -
pubmed
Hyperparathyroidism is a significant problem in the dialysis
patient , despite
phosphate control . -
pubmed
[
Occupational allergy due to inhalation of pollen from
Euphorbia fulgens Karw ( author 's transl ) ] . -
pubmed
The author reviews the structure of
nephropathies on the basis of an analysis of the clinicomorphological data obtained during the follow - up of 3000
patients examined at the nephrological center . -
pubmed
Many
patients with
EMS exhibited clinical and histopathological features similar to another epidemic , the
toxic oil syndrome (
TOS ) , associated with ingestion of adulterated
rapeseed oil . -
pubmed
Patients with
TOS or
EMS had significantly higher
L - kynurenine and
quinolinic acid than healthy control subjects or
rheumatic disease control subjects . -
pubmed
Neopterin was also elevated in
patients with untreated
TOS and
EMS , and correlated strongly with
L - kynurenine and
quinolinic acid . -
pubmed
Genetic contributions to T - cell recognition in
murine lupuslike
autoimmune disease . -
pubmed
Simultaneous , blood pressure became unmeasurable , and the
patient became
cyanosed . -
pubmed
It was concluded that , in our area ,
Streptococcus pyogenes still has an excellent sensitivity to
penicillin G and to other antibiotics which may be a therapeutic alternative in
allergic patients or an empiric treatment in
infections likely to be produced , among other organisms , by
S. - pubmed
In
patients with established
lung disease this is due to a combination of proteolytic degradation , complex with enzyme and oxidation at the active site . -
pubmed
Lymph node biopsies from 43 male homosexuals with persistent generalized
lymphadenopathy and from ten
acquired immunodeficiency syndrome patients , all with serum antibodies to
human T - cell leukemia virus III , were studied with regard to histopathology , immunohistology , and T - cell subsets in cell suspensions . -
pubmed
Our observations indicate the occurrence of marked changes not only in T - cells but also in the B - cell compartment of
patients with persistent generalized
lymphadenopathy or
acquired immunodeficiency syndrome . -
pubmed
Seventy - five percent of
patients experienced relief of symptoms referable to their
ascites . -
pubmed
Significant alterations in coagulation parameters consistent with subclinical
disseminated intervascular coagulation (
DIC ) were present in all
patients with functioning shunts . -
pubmed
The best results can be expected in those
patients with
ovarian and breast primary tumors . -
pubmed
Results of clinico - functional examination in
workers engaged in production of
monomethylaniline semifinished products revealed a more frequent morbidity of the internal organs , moderate
methemoglobinemia , functional changes of the cardio - vascular system ,
disorders of the pulmonary ventilation function , metabolic processes . -
pubmed
Administration of
oestradiol to three
strains of female
mice induced the oestrous phase of the reproductive cycle in which there are few or no polymorphonuclear leucocytes ( PMNL ) in vaginal smears . -
pubmed
BALB / c
mice were the most susceptible , all of 10 becoming colonised ; two other
strains were less susceptible and untreated
mice were resistant . -
pubmed
The numbers of ureaplasmas recovered from the vagina ranged from 10(2 ) to 10(7 ) colour - changing units ( ccu)/ml , irrespective of the
strain of
mice , and in some there was spread to the uterine horns and ovaries , and to the spleen in one
mouse . -
pubmed
Intraperitoneal ( ip ) injection of
cholecystokinin octapeptide sulfate ester (
CCK ; 5 , 10 and 50 micrograms / kg ) reduced the
hypothermic response to 8 mg / kg and 32 mg / kg systemic
morphine in restrained and freely moving
rats , respectively . -
pubmed
The DNA substrates used in binding experiments were two fragments from
Drosophila heat
shock locus 87A7 . -
pubmed
Nearly half of the
patients in the epidural experienced slight
peroperative pain . -
pubmed
DDAVP ( FPA was only measured before DDAVP ) in 20
patients with
diabetes mellitus . -
pubmed
Though clinically normal ,
A - T heterozygotes share a high risk of
cancer with
A - T homozygotes and constitute approximately 1 % of the
human population . -
pubmed
Am J Pathol 64:483 - 500 , 1971 ) liver biopsies of renal transplant
patients who developed chronic progressive
viral hepatitis associated with persistence of Australia antigenemia [ Au(1 ) ] while under immunosuppressive therapy were studied . -
pubmed
To investigate the relationship of these virus - like particles to Australia antigen , 2 of the
Au ( 1 ) hepatitis renal transplant
patients were restudied 6 to 8 months later . -
pubmed
[ Morphology and histochemistry of the jejunal mucosa in
patients with
lactase deficiency ] . -
pubmed
[ The
syndrome induced in the
rat with
dextrans is not
anaphylactic ] . -
pubmed
In order to achieve a more realistic view of the ultrastructural events during
HSV infection of adult tissue , cell cultures were prepared from adult
mouse and
rat livers and infected with several
HSV strains . -
pubmed
Dedifferentiated variants of a
rat hepatoma : reversion analysis . -
pubmed
A rapid liquid chromatographic method for monitoring the 6 neutral
amino acid levels in serum ,
valine ,
leucine ,
isoleucine ,
tyrosine ,
phenylalanine and
methionine , has been developed for use as one of the routine clinical laboratory tests for
patients with severe
liver disease requiring urgent treatment . -
pubmed
This simple method would provide much valuable information for the selection of therapy , prediction of impending
coma and evaluation of the
patient 's response to treatment , as well as an analysis of pathophysiology and prognosis . -
pubmed
Postnatal development of spiral
ganglion cells in the
rat . -
pubmed
The postnatal development of the spiral
ganglion in the albino
rat was studied using light and
electron microscopy . -
pubmed
[ Errors in the diagnosis of
chronic hepatitis in
children ] . -
pubmed
[ Susceptibility to murine
leprosy bacilli of C3H / H3
mice ( author 's transl ) ] . -
pubmed
Similarly , there was no significant difference between the survival of
patients with stage B or stage C
tumours regardless of whether their levels of the antigen were greater or less than 10 ng / mL of plasma . -
pubmed
Organ - related and
malignancy - associated reactivity of
cancer patients ' leucocytes : a leucocyte migration study with
tumour and foetal extracts . -
pubmed
Leucocytes from
patients with a variety of
tumours including gastric , colorectal , lung , kidney and
mammary cancer , were tested in the leucocyte migration test ( LMT ) against organ - related and non - organ - related
tumour and foetal extracts . -
pubmed
The reactivity of
cancer patients ' leucocytes against a panel of organ - related
tumour extracts was found to be 71 - 93 % , depending on the
tumour system tested . -
pubmed
Cross - reactivity with a panel on non - organ - related
tumour extracts was found in 0 - 38 % of
patients . -
pubmed
The result of pathologic examination indicates that Hongning Gantai can alleviate
liver damages of
mice and
rats and thus has liver - protecting and
ALT - lowering actions . -
pubmed
Food allergy was investigated in 20
children with
cystic fibrosis (
CF ) , who still suffered from
diarrhea and failed to thrive , in spite of adequate diet and enzyme treatment ( group A ) . -
pubmed
The study also included two age - matched control groups , comprising 10
CF children without
intestinal symptoms and/or failure to thrive ( group B ) , and 20 healthy
children ( group C ) . -
pubmed
Symptoms improved in 90 % of
CF patients ( group A ) when the implicated foods were eliminated from the diet and in 78 % the oral provocation test resulted positive . -
pubmed
PURPOSE : The prognosis of
patients with multifocal primary and early or multiple relapsed
Ewing ' s sarcoma is poor with conventional chemoradiotherapy and surgery . -
pubmed
Seven
patients had multifocal primary
Ewing ' s sarcoma , and 10 had early or multiple
relapse . -
pubmed
RESULTS : The probability of
relapse in the study
patients is 52 % at 6 years after the last event before transplantation . -
pubmed
Probability of
relapse - free survival in the study
patients is 45 % + /- 12 % at 6 years after the last event before transplant , compared with 2 % + /- 2 % for the historic control group . -
pubmed
Using a multidisciplinary approach , we have measured various indicators of DNA damage in peripheral lymphocytes of
human populations potentially at increased risk for
cancer . -
pubmed
A prospective , longitudinal study was performed to identify environmental factors that modulate genetic damage in
breast cancer patients . -
pubmed
Women with
benign breast masses and no apparent disease served as controls . -
pubmed
A discrete group of melanin containing cells are coincident with a major reorganization of retinal
ganglion cell axons in the optic nerve of
Xenopus . -
pubmed
A phase I clinical trial of a combination of
mitoxantrone ,
5 - fluorouracil , and high - dose
leucovorin given on a day 1 and day 8 schedule to
patients with metastatic
breast cancer . -
pubmed
Platelet toxicity and more profound
granulocyte toxicity appeared to occur in
patients with
liver metastases . -
pubmed
Tissue markers of potentially malignant
human oral epithelial lesions . -
pubmed
Current research has provided some provocative results , suggesting an association between
human papillomavirus (
HPV ) and development of
squamous cell tumors including
oral cancer . -
pubmed
However , considering the many similarities between oral and cervical
oncogenesis , many of the
HPV induced changes in the cervix may also be applicable to the oral mucosa . -
pubmed
This paper studies the evidence for the possible role of
HPV infection in oral
carcinogenesis , the uterine cervix as a model for
HPV mediated
carcinogenesis , and tries to determine if similar mechanisms could exist in both cases . -
pubmed
Islet viability was assessed by syngeneic transplantation to the renal subcapsular space of
streptozotocin - induced
diabetic rats . -
pubmed
Twelve
patients with suspected
SO dysfunction were investigated . -
pubmed
A study of radiation
necrosis and
edema in the
canine brain using positron emission tomography and magnetic resonance imaging . -
pubmed
Radiation injury , a major hazard of central nervous system ( CNS ) radiotherapy , was investigated using sequential studies with positron emission tomography ( PET ) and magnetic resonance imaging ( MRI ) in
beagle dogs with both
helium and neon - ion hemibrain irradiation . -
pubmed
All
dogs receiving 7.5 - 11 Gy of neon showed no signs of
radiation injury to 3 years after irradiation . -
pubmed
Dogs receiving & gt ; or = 13 Gy neon or
helium succumbed to radiation
necrosis and died 21 - 32 weeks after irradiation . -
pubmed
The findings of imaging studies for all
dogs who succumbed to radiation
necrosis were normal until 3 - 6 weeks before death . -
pubmed
The present report describes a
patient with moderately severe idiopathic
aplastic anaemia who was managed with intensive haematological support leading to delivery of a healthy infant by caesarean section . -
pubmed
We analyzed the pattern of failure and clinicopathologic factors influencing the
disease - free survival of 78
patients who died after macroscopic curative resection for
pancreatic cancer . -
pubmed
Local
recurrence was a component of failure in 56
patients ( 71.8 % ) and hepatic
recurrence in 48 ( 61.5 % ) , both accounting for 97 % of the total
recurrence rate . -
pubmed
From our experience and the data collected from the literature , it appears that surgery alone is an inadequate treatment for cure in
patients with
pancreatic carcinoma . -
pubmed
In pithed
Wistar Kyoto ( WKY ) and spontaneously
hypertensive ( SHR )
rats , electrical ( 1 Hz , 1 ms , 50 V for 10 s ) stimulation increased
diastolic blood pressure by 28 and 37 mmHg , respectively . -
pubmed
The inhibitory influence of
imetit was diminished by
thioperamide 1 mumol / kg to about the same degree in
rats of either
strain . -
pubmed
One
patient ( 18 years old ) developed
recurrence and died due to extensive infiltration into the maxilla and mandible . -
pubmed
Two
patients ( 57 and 62 years ) developed multiple
myeloma one to two years after the excision of
tumors , and both died two to three months later . -
pubmed
CONCLUSION : The smears from all 13
patients were diagnosed as
extramedullary plasmacytomas by fine needle aspiration cytology . -
pubmed
RESULTS : Among the 512
patients were 9 with
gastrinomas . -
pubmed
In the second group of
gastrinoma patients all had a degree of amidation of less than 50 % . -
pubmed
Effect of
tumor bulk on local control and survival of
patients with
T1 glottic cancer . -
pubmed
Seventy - seven
patients had small lesions and 37 had bulky
tumors . -
pubmed
The anterior commissure was involved with
cancer in 43
patients . -
pubmed
The 5 - year actuarial survival for all
patients was 73 % and the
disease - free survival was 92 % . -
pubmed
Patients who had bulky
tumors had lower local control and
disease - free survival rates than those
patients who had small
tumors . -
pubmed
Effects of
Ramipril and
Isradipin on hemorheological profiles in
patients with
arterial hypertension . -
pubmed
Although in the T - IAA group 4 of the 29
patients ( 13.8 % ) displayed partial
incontinence ( & lt ; 9 points ) , all of 8
patients in the
DS - IAA group showed good results referring to continence ( & gt ; 10 points ) . -
pubmed
Epstein - Barr virus (
EBV ) seronegativity is rare in adults . -
pubmed
DNA fragmentation precedes aberrant expression of cell cycle - related protein in
rat brain after
MCA occlusion . -
pubmed
Except for a small subset of
patients with
angina whose survival is improved with coronary artery bypass surgery ,
chronic stable angina can be appropriately managed with medical therapy in the vast majority of
patients . -
pubmed
Drug therapy includes
aspirin , beta - adrenergic blockers ,
cholesterol - lowering agents and other anti -
ischemic drugs that can ameliorate
angina and improve the
patient 's quality of life . -
pubmed
Plasma
homocysteine is decreased in the
hypothyroid rat . -
pubmed
Recent clinical studies have indicated that plasma
homocysteine was significantly increased in
hypothyroid patients . -
pubmed
Since
hyperhomocysteinemia is an independent risk factor for
cardiovascular disease we investigated
homocysteine metabolism in
hypothyroid rats . -
pubmed
Unlike the
human hypothyroid patients , both groups of
hypothyroid rats exhibited decreased total plasma
homocysteine ( 30 % in
PTU rats , 50 % in thyroidectomized
rats ) versus their respective controls . -
pubmed
The
hypothyroid rat can not be used as a model to study
homocysteine metabolism in
hypothyroid patients . -
pubmed
The markedly high levels of polymorphism present in classical class I loci of the
human major histocompatibility complex have been implicated in infectious and
immune disease recognition . -
pubmed
We describe a 34 - year - old female
patient with "
primary antiphospholipid syndrome " and
portopulmonary hypertension . -
pubmed
Influence of highly active anti - retroviral therapy on response to treatment and survival in
patients with
acquired immunodeficiency syndrome - related
non - Hodgkin ' s lymphoma treated with
cyclophosphamide ,
hydroxydoxorubicin ,
vincristine and
prednisone . -
pubmed
We analysed the influence of HAART on the response to treatment and survival in a series of 58
patients with
acquired immune deficiency syndrome (
AIDS)-related
non - Hodgkin ' s lymphoma (
NHL ) treated with CHOP (
cyclophosphamide ,
hydroxydoxorubicin ,
vincristine and
prednisone ) . -
pubmed
Two groups of patients were included : ( i ) forty - one
patients diagnosed with
NHL between 1988 and 1996 who were not treated with HAART ; ( ii ) seventeen
patients diagnosed since 1996 , who were receiving or commenced HAART when
NHL was diagnosed . -
pubmed
Improvement was observed in the group of
patients with very mild to mild
cognitive impairment , while in more severe
dementia , the mean EGb effect should be considered more in terms of stabilization or slowing down of worsening , as compared to the greater deterioration observed with placebo . -
pubmed
Mixed
infection of
HBV / G and
HBV / A , as well as the recombination , was demonstrated in the sequence of preS1 and preS2 regions also . -
pubmed
Coinfection with
HBV / G and
HBV / A was demonstrated in the other three patients , and their recombination in two patients . -
pubmed
In conclusion ,
HBV / G is frequently found as a
coinfection with
HBV / A. -
pubmed
METHODS : A total of 50
patients with clinically non - functional
pituitary macroadenomas were treated by transsphenoidal tumour resection and were examined by MRI before and directly after surgery ( early MR ) and 3 months ( intermediate MR ) and 1 year after surgery ( late MR ) . -
pubmed
On the intermediate MR images residual
tumour tissue was detected in 30 % of the
patients ( 4 intrasellar , 2 suprasellar and 9 parasellar ) . -
pubmed
Before surgery the pituitary gland was visible superiorly or posterosuperiorly to the
macroadenomas in 35
patients . -
pubmed
Electromyographic activity associated with spontaneous functional recovery after
spinal cord injury in
rats . -
pubmed
This investigation was designed to study the spontaneous functional recovery of adult
rats with incomplete
spinal cord injury (
SCI ) at thoracic level during a time course of 2 weeks . -
pubmed
Directly after
SCI , a marked drop in locomotor ability occurred in all
rats with subsequent partial recovery over 14 days . -
pubmed
Histology of a skin biopsy showed naked noncaseating
granulomata and PCR for
Mycobacterium tuberculosis was negative . -
pubmed
We discuss the presentation and management of
sarcoidosis in
children , and highlight the potential difficulty in differentiating this from disseminated
tuberculosis . -
pubmed
METHODS : We examined 128 Czech
patients with
ADPKD ( 62
males , 66 females ) and 93
patients with
IGAN ( 51 males , 42 females ) . -
pubmed
OBJECTIVES : To investigate the effects of treatment with nebulised hypertonic saline on
people with
CF compared to placebo and or other treatments that enhance mucociliary clearance . -
pubmed
At this stage there is insufficient evidence to support the use of hypertonic saline as routine treatment for
people with
cystic fibrosis . -
pubmed
There were 77
persons without
dementia and 51 with probable
AD ; 38 participants had one or more epsilon4 alleles . -
pubmed
Strain M25 extracts also contained small quantities of the
streptin 1 and streptin 2 peptides in various stages of
dehydration . -
pubmed
Rats were perfused at 2 hours after
inflammation , and brainstem tissues were processed for Fos - Fluorogold double immunocytochemistry . -
pubmed
Effect of
atherosclerosis and age upon the serum mucoprotein and
hexosamine levels in
man . -
pubmed
EXPERIMENTAL
MANGANESE ENCEPHALOPATHY IN
MONKEYS . -
pubmed
BACKGROUND AND OBJECTIVE : To evaluate the reproducibility of full - field perfusion analysis using scanning laser Doppler flowmetry ( SLDF ) for perfusion measurements of the neuroretinal rim of the optic nerve head and the peripapillary retina in
patients with
open - angle glaucoma or
ocular hypertension , and in normal subjects . -
pubmed
PATIENTS AND METHODS : SLDF perfusion measurements of the neuroretinal rim and the peripapillary retina were performed on 20
patients with
open - angle glaucoma or
ocular hypertension ( group G ) and 20 normal
volunteers ( group N ) . -
pubmed
METHODS : Two hundred twenty
women , ages 18 to 49 years , with
PAOD and 629 healthy
women ( control group ) from a population - based case - control study filled out the same structured questionnaire and donated venous blood samples for determination of plasma
homocysteine levels . -
pubmed
RESULTS : Young
women with
hyperhomocysteinemia had a 2.5 - fold ( 95 % confidence interval [ CI ] , 1.7 - 3.9 ) increased risk for
PAOD . -
pubmed
METHODS : One hundred and twenty - six
diabetic patients without
CHD and 41
patients with
CHD were recruited from our hospital . -
pubmed
Transient
hyperthyroidism after withdrawal of antithyroid drugs in
patients with
Graves ' disease . -
pubmed
The development of silent
thyroiditis in
patients with a history of
Graves ' disease is common , especially in the postpartum period . -
pubmed
If such
patients are diagnosed as
recurrence of
Graves ' disease , they may receive
ATD or
radioiodine therapy unnecessarily . -
pubmed
We retrospectively studied 22
patients with
Graves ' disease who showed transient
thyrotoxicosis after withdrawal of
ATD . -
pubmed
Most of the 22
patients became
euthyroid within 6 months . -
pubmed
This study suggests a new therapeutic option as follows : in the case of young
patients with mild
thyrotoxicosis after withdrawal of
ATD , physicians should follow them up for one month without medication unless they have unbearable symptoms or complications . -
pubmed
We report here about two
patients with clinically suspected diagnosis of a
Takayasu ' s arteritis already under anti - inflammatory therapy in whom percutaneous transluminal atherectomy of subclavian and axillary artery
stenoses was performed to relief the
patients from symptoms -- intermittent
dyspraxia of the arms -- and to verify the clinical diagnosis by histology . -
pubmed
On the 6th postoperative day , the
patient experienced
tightness of the chest and
nausea after receiving a transfusion of fresh frozen plasma ( FFP ) . -
pubmed
Duodenal
ulcers were induced in
rats by
cysteamine with or without
CFTR ( inh )- 172 pretreatment 1 h before
cysteamine . -
pubmed
Human gastric cancer xenografts
SC-2 ,
St-40 , and
SC-4 inoculated into
nude rats were treated with
TS-1 alone (
TS-1 12 mg / kg / day , day 1 - 14 ) ,
TXT alone (
TXT 2 mg / kg / day , day 1 or day 8) , and combination of both drugs . -
pubmed
Twenty eight
people were recorded as having a total of 45
seizures ( 23 before starting
bupropion , two in the first 28 days of treatment , and 20 at a later point ) . -
pubmed
An 83 - year - old
woman died as a result of an anastomotic
dehiscence ; the six other
deaths resulted of cardiopulmonary complications . -
pubmed
Postoperative morbidity was 15 % ( 11
patients ) including two
fistulas , which recovered without surgery . -
pubmed
A randomized , double - blind , placebo - controlled trial of
duloxetine in the treatment of
women with
fibromyalgia with or without major
depressive disorder . -
pubmed
This was a 12 - week , randomized , double - blind , placebo - controlled trial to assess the efficacy and safety of
duloxetine , a selective
serotonin and
norepinephrine reuptake inhibitor , in 354 female
patients with
primary fibromyalgia , with or without current major
depressive disorder . -
pubmed
MATERIAL AND METHOD :
Patients with
Sicca ' s Syndrome from the Stomathology service , Santa Casa de Misericordia Hospital , in Sao Paulo , ENT Department , from July 1999 to April 2002 . -
pubmed
A 70 - year - old
woman with
acute renal failure . -
pubmed
The reason why only a few
patients with
multiple myeloma develop
CSH , while the majority do not , is unknown , but it may at least partially reflect a defect in intralysosomal degradation because simple light chain overproduction is not sufficient for the development of
CSH . -
pubmed
Interestingly ,
CSH is associated with improved survival in
multiple myeloma patients , perhaps due to earlier detection and treatment of
myeloma because of the symptoms associated with
CSH . -
pubmed
In this case report , we discuss the presentation and management of
pancreatic adenocarcinoma , with
lung and liver metastases , diagnosed in a
woman in her third trimester of pregnancy ( 28 weeks ) . -
pubmed
In both models , and particularly in each of three , independent in vitro
infection experiments , this assay permitted the quantitation of
HCV replication . -
pubmed
Humans can be infected with
RVF virus from
bites of mosquitoes or other arthropod vectors that have fed on animals infected with
RVF virus , or through contact with viremic animals , particularly livestock . -
pubmed
Multicolour FISH in an analysis of
chromosome aberrations induced by
N - nitroso - N - methylurea and
maleic hydrazide in
barley cells . -
pubmed
METHODS :
Human hepatocellular carcinoma was induced in
nude mice , and the
mice were randomly divided into group A receiving normal saline , group B receiving magnetic nanoparticles containing
5 - fluorouracil ( 5 - FU ) , group C receiving 5 - FU , and group D receiving magnetic nanoparticles containing 5 - FU with a magnetic field built in
tumor tissues . -
pubmed
Metabolic acidosis : new insights from
mouse models . -
pubmed
Comparative proteomic analysis of
human adenomyosis using two - dimensional gel electrophoresis and mass spectrometry . -
pubmed
Five of them were histologically diagnosed with
adenomyosis and the other five age - matched
patients had
cervical carcinoma in situ . -
pubmed
She had a history of
infective endocarditis caused by
methicillin - sensitive
Staphylococcus aureus a year ago . -
pubmed
Increased cardiovascular risk in
patients with
human immunodeficiency virus infection under highly active antiretroviral therapy . -
pubmed
Unrelated umbilical cord blood transplantation using a
TBI / FLAG conditioning regimen for
adults with
hematologic malignancies . -
pubmed
CASE OUTLINE : This article presents a case of a young
female with
schizophrenia , without clinical improvement with several antipsychotics (
clozapine ,
risperidone ,
haloperidol ) and with the occurrence of significant neurological side effects . -
pubmed
85 consecutive
patients ( 90 knees ) were enrolled , who were available at 1 - year follow - up after a medial opening wedge high tibial osteotomy using a kinematic navigation system or a conventional method , for medial unicompartmental
osteoarthritis . -
pubmed
PATIENTS AND METHODS : Chemotherapy - naive
patients with histo-/cytologically proven unresectable
APC , and bi - dimensionally measurable diseases were eligible . -
pubmed
However ,
nontuberculous mycobacterial infection diagnosed with FNAB material is much rarer , with
Mycobacterium avium complex being the most common . -
pubmed
When faced with antibiotic - resistant
cellulitis and
abscesses , the FNAB material must be sent for acid fast
bacteria smears and culture . -
pubmed
CONCLUSIONS : This trial of myoblast transplantation via catheter into
heart failure patients demonstrated safety and feasibility . -
pubmed
Treated
patients showed improvement in NYHA , MLHFQ , ventricular viability , and evidence of reverse
ventricular remodeling . -
pubmed
Decreased cell proliferation in the dentate gyrus does not associate with development of
anhedonic - like symptoms in
rats . -
pubmed
Nevertheless , several reports have recently pointed out that , in
rodent models of
depression , suppression of generation of new hippocampal neurons is not by itself sufficient to induce the development of
depression - related symptoms . -
pubmed
In the present study , we used the cell proliferation blocker
methylazoxymethanol (
MAM ) and the
rat chronic mild stress ( CMS ) model of
depression to challenge the neurogenic theory of
depression . -
pubmed
Unlike CMS , chronic injections with
MAM did not induce
anhedonia - like symptoms in
rats . -
pubmed
Our results show that suppression of cell proliferation in the hippocampal formation is not an absolute factor for induction of an
anhedonia - like state in
rats . -
pubmed
We found that neonatal
dusky sharks (
Carcharhinus obscurus ) are not independent from maternal resource allocation at the point of parturition but instead are provisioned with energy reserves in the form of an
enlarged liver that constitutes approximately 20 % of total body mass . -
pubmed
Some
patients need sleep therapy as well as anti -
depressive therapy . -
pubmed
To characterize the molecular mechanisms involved in the transition from the chronic phase to
blast crisis in
chronic myelogenous leukemia (
CML ) , gene expression profiles of leukemic cells from
patients in the chronic and
blast crisis phases were analyzed using an 8.7 K cDNA chip and real - time PCR . -
pubmed
These results may help in the prediction of disease progression in
CML patients and the development of more appropriate therapeutic modalities . -
pubmed
All
children who suffered a superficial partial - thickness
scald injury were included . -
pubmed
OBJECTIVE : To describe an unusual case of
lateral neck swelling in a
patient with a permanent cardiac pacemaker . -
pubmed
CASE REPORT : We describe a
patient who presented with a painful , lateral neck
swelling due to an internal jugular vein
thrombus . -
pubmed
CONCLUSION : There was a high frequency of behavioral risk factors , together with unawareness , and very little health infrastructure , thus creating an impending risk for the rapid spread of
HIV /
AIDS (
acquired immunodeficiency syndrome ) . -
pubmed
Optical Coherence Tomography Findings in
Patients with
Degenerative Retinoschisis and Symptomatic
Retinal Detachment . -
pubmed
This article describes the optical coherence tomography ( OCT ) findings in 4
patients with
degenerative retinoschisis and symptomatic
retinal detachment . -
pubmed
During the last nine years ( 1986 to 1994 ) the authors treated 27
children with
injuries of the proximal growth plate of the tibia , i. e. 0,8 % of all
skeletal injuries treated during the above period at the clinic . -
pubmed
In the total number of patients one complication of partial growth stimulation occured with a subsequent
angulation deformity of the proximal tibia ( 4,5 % ) and in one instance ( 4,5 % ) an early complication in a
patient with a devastating
injury of the leg and dorsum of the foot where the combined affection of the popliteal artery in the dislocated
fracture of the proximal epiphysis of the tibia and the devastating
injury of the leg led to a subsequent uncontrollable anaerobic
infection , which called for
amputation of the leg . -
pubmed
Tyrosine monitoring in
children with early and continuously treated
phenylketonuria : results of an international practice survey . -
pubmed
This paper provides a snapshot of current practice in the monitoring and/or treatment of
tyrosine levels in
children with
PKU , across 12 countries from Australasia , North America and Europe . -
pubmed
[ Effect of Bushen Huoxue recipe on the state of extracellular matrix in
glomerulosclerosis rats model ] . -
pubmed
OBJECTIVE : To investigate the effect and acting mechanism of Bushen Huoxue Recipe ( BHR ) on the state of extracellular matrix in
glomerulosclerosis (
GS )
rats model . -
pubmed
Compounds show in - vitro antiproliferative activity against some
human cancer cell lines . -
pubmed
METHODS : Twenty
varicose vein specimens were atraumatically harvested from 20
women undergoing lower extremity primary
varicose vein excision . -
pubmed
The
patients were divided into groups according to age ( & lt;50 years , & gt;50 years ) and the presence of leg
edema (
CEAP , class 2 or 3 ) . -
pubmed
CONCLUSION : Age of the
patient may affect the remodeling of
varicose veins and SMC quantity in the media layer was found decreased in
patients with
edema . -
pubmed
Mouse and
fruit fly CD knock - out models have highlighted the multi - pathophysiological roles of
CD in tissue homeostasis and organ development . -
pubmed
Here we report the first phenotypic description of the lack of CD expression during
zebrafish (
Danio rerio ) development obtained by
morpholino - mediated knock - down of
CD mRNA . -
pubmed
Our findings add to the list of
CD functions in organ development and patho - physiology in
vertebrates . -
pubmed
Francisella asiatica as the causative agent of
piscine francisellosis in cultured tilapia ( Oreochromis sp . ) -
pubmed
Francisella asiatica is a Gram - negative , pleomorphic , facultative intracellular , bacterial pathogen that causes acute to
chronic disease in a wide variety of warm - water cultured and wild fish species . -
pubmed
Outbreaks of
francisellosis in warm water fish have been documented in Taiwan , Japan , United Kingdom , Hawaii , and Latin America ( including Costa Rica ) but the organism has only been reported from the United States on one occasion from hybrid
striped bass in California . -
pubmed
BACKGROUND : Adjuvant therapy is not usually recommended in
AJCC T2N0M0
gastric cancer , yet sometimes is indicated for high - risk
patients . -
pubmed
METHODS : We analyzed our documented clinical database of 233
patients with T2N0M0
gastric cancer who underwent radical resection between 2000 and 2007 . -
pubmed
CONCLUSION :
Patients with T2N0
gastric cancer have a favorable prognosis after radical resection . -
pubmed
A prognostic risk model of
patients with pT2N0
gastric cancer undergoing radical resection is constructed based on lymphatic and/or blood vessel invasion ,
tumor diameter , and perineural invasion . -
pubmed
The prognostic risk model identifies a small subgroup of
patients with an increased risk of
death , suggesting adjuvant therapy may be considered for these
patients . -
pubmed
Over the last decade , several rhythm - versus rate - control trails in
patients with
atrial fibrillation (
AF ) have failed to demonstrate benefit of the rhythm control strategy with respect to mortality and morbidity . -
pubmed
Currently ,
dronedarone is the only available antiarrhythmic drug which has shown a reduction in cardiovascular hospitalizations in medium - risk
AF patients . -
pubmed
However , the drug was associated with increased mortality in
patients with recently decompensated
heart failure . -
pubmed
Hence , antiarrhythmic drug therapy has to be evaluated in
patients with
AF on an individual
patients basis . -
pubmed
These are important considerations for communities hard - hit by HIV and
AIDS , given the extent and nature of deprivation , the long - term risk to
human capital and the current political willingness to act . -
pubmed
We report the case of a 45 - year - old
woman with chronic
HIV infection and
personality disorder , who after 12 months of
tenofovir , complained of
fatigue , diffuse
bone pain and
gait disturbances . -
pubmed
Vascular restenosis is affecting 30 - 40 % of
patients treated by percutaneous coronary angioplasty ( PTCA ) . -
pubmed
Alpha - lipoic acid (
ALA ) , a natural antioxidant , is widely used for the treatment of some diseases including
diabetes , and
decursinol ( DA ) , a constituent of root of
Angelica gigas Nakai , has some pharmacological activities including anti - inflammatory function . -
pubmed
Included are 680
ADPKD adults who provided data on blood pressure , renal volume , renal function ,
uric acid , age at the onset of
ESRD or last known age without
ESRD . -
pubmed
The study includes 10 non - pregnant
women , 50 normal pregnancy , and 110 preeclamptic (
PE )
women at the same period of pregnancy . -
pubmed
Efficacy and safety of oral chelators in treatment of
patients with
Wilson disease . -
pubmed
We assessed the safety of
D - penicillamine and
trientine therapy and outcomes of
patients with
Wilson disease . -
pubmed
METHODS : We performed a retrospective analysis of data on 380
patients with
Wilson disease from tertiary care centers in Germany and Austria , and 25 additional
patients from the EUROWILSON registry . -
pubmed
Forty - eight months after therapy ,
hepatic deterioration was reported in only 4 of 333
patients treated initially with a chelating agent . -
pubmed
However ,
neurologic deterioration was observed less frequently in
patients given
D - penicillamine first ( 6 of 295 ) than those given
trientine first ( 4 of 38 ; P = .018 ) . -
pubmed
CONCLUSIONS : Chelating agents are effective therapies for most
patients with
Wilson disease ;
D - penicillamine and
trientine produce comparable outcomes , although
D - penicillamine had a higher rate of adverse events . -
pubmed
Few
patients receiving chelation therapy had
neurologic deterioration , which occurred more frequently in
patients who received
trientine . -
pubmed
Patients consistently treated with European
AIDS Clinical Society ( EACS ) 2008 guidelines were 255 ( 76.6 % ) , of whom 202 ( 79.2 % ) with an indication to an anti -
HIV treatment , 30 ( 11.8%)without an indication , and 21 ( 8.2 % ) with
cirrhosis . -
pubmed
Previous anti -
HBV treatment ( p = 0.01 ) and a triple
HDV co - infection ( p = 0.03 ) reduced the chance of not - consistent regimens . -
pubmed
To the best of our knowledge , this is the first study using barcoded DNA pyrosequencing method to survey the ileal microbiome of
goats and the results suggest that increasing levels of dietary
corn change the composition of the ileal bacterial community . -
pubmed
This study investigated long - term cellular and humoral immunity against
pertussis after booster vaccination of 4 - year - old
children who had been vaccinated at 2 , 3 , 4 , and 11 months of age with either whole - cell
pertussis ( wP ) or acellular
pertussis ( aP ) vaccine . -
pubmed
CDAD was defined as & gt;=3 episodes of loose stools in & lt;24 h with a positive
Clostridium difficile stool toxin assay . -
pubmed
Bleeding complications in
patients with coronary stents during non - cardiac surgery . -
pubmed
The type of procedure , perioperative antiplatelet therapy , and other
patient - related factors influence the risk of
postoperative haemorrhage . -
pubmed
Our objective was to analyze the postoperative risk factors for
hemorrhagic complications and to determine the impact of antiplatelet and anticoagulant therapy strategies on
postoperative bleeding risk in
patients with coronary stents undergoing non - cardiac surgery . -
pubmed
RESULTS : Among the 1134
patients evaluated , 108 ( 9.5 % ) experienced a postoperative
hemorrhagic complication ( with a median time to occurrence of 5.3days ) . -
pubmed
Mortality in
patients with a
haemorrhagic complication was 12 % ( n=13 ) . -
pubmed
When interrupted before the procedure , resumption of antiplatelet treatment was delayed in
patients developing early postoperative
hemorrhagic complications . -
pubmed
CONCLUSION :
Patients with coronary stents who undergo surgery are at high risk for
hemorrhagic complications . -
pubmed
Bazedoxifene versus oral
bisphosphonates for the prevention of
nonvertebral fractures in postmenopausal
women with
osteoporosis at higher risk of
fracture : a network meta - analysis . -
pubmed
OBJECTIVE : To compare the efficacy of
bazedoxifene and oral
bisphosphonates for the prevention of
nonvertebral fractures (
NVFs ) in
women with higher risk of
postmenopausal osteoporosis ( i.e. -
pubmed
A subgroup of
patients with a FRAX score of 20 % or more in the
bazedoxifene phase III
osteoporosis study was selected as the population of interest on the basis of the
bazedoxifene label . -
pubmed
PE /
ARDS alone in
Plasmodium vivax may result in mortality , whereas multiorgan involvement is common in
P. - pubmed
Association of
Epstein Barr virus A73 gene polymorphism with
nasopharyngeal carcinoma . -
pubmed
METHODS : A case - control study was designed , including 510
nasopharyngeal cancer patients and 520 healthy controls , A157154C genotypes of the A73 gene in EB virus were detected , genotype and allele frequency distribution between the two groups were compared . -
pubmed
The present study was undertaken to evaluate the antinociceptive properties of
physalins B ( 1 ) , D ( 2 ) , F ( 3 ) , and G ( 4 ) isolated from
Physalis angulata in inflammatory and centrally mediated
pain tests in
mice . -
pubmed
Here , we report a rare case of
Sweet ' s syndrome induced by
azathioprine in a
patient with
Crohn ' s disease . -
pubmed
Efficacy of
chlorhexidine and
green tea mouthwashes in the management of
dental plaque - induced
gingivitis : A comparative clinical study . -
pubmed
The antibacterial and antioxidant properties of
green tea were found to be beneficial in the treatment of
gingival and periodontal diseases . -
pubmed
The aim of this comparative study was to compare the efficacy of the mouthwash containing
green tea and
chlorhexidine in the management of
dental plaque - induced
gingivitis . -
pubmed
However ,
green tea mouthwash resulted in a statistically significant decrease in
bleeding index compared to
chlorhexidine group . -
pubmed
CONCLUSION : The
green tea - containing mouthwash is equally effective in reducing the
gingival inflammation and plaque to
chlorhexidine . -
pubmed
METHODS :
Patients with
STEMI treated with thrombolysis followed by percutaneous coronary intervention ( PCI ) were randomly assigned to receive either BMMNC or saline as an intracoronary injection . -
pubmed
We compared the
lomustine ,
cytarabine ,
cyclophosphamide and
etoposide (
LACE ) and
BCNU ,
etoposide ,
cytarabine ,
melphalan (
BEAM ) conditioning regimens for
toxicity , engraftment kinetics , and efficacy in 139
patients undergoing autologous hematopoietic stem cell transplant for primary refractory or
relapsed lymphoma . -
pubmed
Ninety - two
patients with
Hodgkin lymphoma and 47 with
non - Hodgkin lymphoma were enrolled . -
pubmed
It was related most closely to the type
strain of
Sedimentibacter saalensis ( 94 % sequence similarity ) . -
pubmed
The type
strain is
MO - SEDIT ( = JCM 17293 T = DSM 24004 T ) . -
pubmed
OBJECTIVE : To assess the ability of semen analysis and other
patients ' characteristics to predict the presence of spermatozoa in radical orchiectomy pathological specimen , and describe potential implications for
patients with
azoospermia and
testis cancer . -
pubmed
PATIENT(S ): A total of 214 consecutive
patients with
testicular cancer who underwent radical orchiectomy between 1997 and 2015 . -
pubmed
Given the substantial likelihood ( ~60 % ) of spermatozoa to be present in the cancerous testis of
patients with
azoospermia and
cryptozoospermia , concomitant oncologic testicular sperm extraction ( TESE ) can be considered in these selected
patients . -
pubmed
OBJECTIVE : In
patients with
subpulmonic infundibular ventricular septal defect (
VSD ) , postoperative progression of
aortic regurgitation (
AR ) sometimes occurs despite early operation before the development of
AR . -
pubmed
CONCLUSIONS : Among
patients with subpulmonic infundibular VSD , the incidence of late
AR progression after VSD repair alone was unexpectedly high ( 7.7 % ) . -
pubmed
Children aged 2 - 18 years ( N = 108 ) with suspected
OSA underwent overnight simultaneous oximetry and actigraphy at home on a single night . -
pubmed
Diagnostic value of trunk flexion - extension testing in old
chronic low back pain patients . -
pubmed
PURPOSE : Dynamic trunk flexion - extension testing has been proven to objectively diagnose
low back pain in persons under the age of 60 years but older
persons have difficulty complying with standardized movement velocity . -
pubmed
A 48 - year - old
woman underwent a total abdominal hysterectomy after preoperative diagnosis of multiple
uterine leiomyomas . -
pubmed
The
patient was also diagnosed with
pelvic bone metastasis and received six cycles of adjuvant chemotherapy with
gemcitabine plus
docetaxel and local radiation therapy to control the
pain . -
pubmed
The
patient underwent a craniotomy and resection of the lesion , which was a confirmed
metastasis from
uterine LMS by histopathology . -
pubmed
One month after the craniotomy , the
patient experienced lower
abdominal pain , and a
pelvic metastasis was detected . -
pubmed
METHODS AND MATERIALS : Six consecutive clinical stage I , grade 1 - 2 , medically inoperable
endometrial cancer patients were treated with triple - tandem HDR brachytherapy . -
pubmed
We report
patient factors and
acute toxicity . -
pubmed
Patient comorbidities included morbid
obesity ,
congestive heart failure ,
diabetes , and
pulmonary emboli . -
pubmed
CONCLUSIONS : In medically inoperable , clinical stage I
endometrial cancer patients with multiple comorbidities , definitive triple - tandem , HDR brachytherapy results in mild acute
toxicity . -
pubmed
An unexpected finding in a
man with
multiple pulmonary nodules , a
pleural effusion and
respiratory failure . -
pubmed
We report the case of a 47 - year old Caucasian
man with a history of
depression and high
alcohol intake who presented with a one - month history of
weight loss ,
dry cough and
abdominal pain . -
pubmed
We discuss this unexpected finding and review the literature on Bovine
Tuberculosis in
humans . -
pubmed
METHODS : We re - abstracted the medical records of a random sample ( n = 520 ) of metastatic
melanoma patients who had been diagnosed in 2011 and reported to population - based registries in the U.S. We also queried their treating physicians . -
pubmed
Records of
children treated for
achalasia , over an 18 - year period , were reviewed . -
pubmed
Twenty - eight
patients were initially treated with Heller 's myotomy ( HM ) and 20 with
balloon dilatation (
BD ) . -
pubmed
All
children who underwent BD required HM due to symptom
recurrence . -
pubmed
Of 108 procedures ,
esophageal perforation occurred in two
children after HM ( two out of 48 HM procedures in total , 4 % ) and one child after BD ( 1/60 , 1.7 % ) . -
pubmed
CONCLUSION : Less than half of
children with
achalasia are symptom free after initial treatment with either BD or HM . -
pubmed
METHOD : We conducted a 6 - year prospective observational study on 20 pregnant
women in whom uncomplicated simple
appendicitis ( appendiceal diameter & lt;=11 mm and with no signs of
appendicoliths ,
perforation , or
abscess ) was radiologically verified and managed with a 4 - day course of antibiotics . -
pubmed
Three
patients failed to respond to antibiotic therapy during hospitalization and underwent subsequent appendectomy ( 2 suppurative and 1 perforated
appendicitis ) . -
pubmed
Inclusion criteria were treatment - naive
children with isolated
nonsyndromic trigonocephaly , being treated with standardized frontoorbital advancement in our department . -
pubmed
One
patient suffered from a small inconsequential subdural
hematoma . -
pubmed
Another
patient suffered from
dural tears , which were identified and treated intraoperatively . -
pubmed
A meta - analysis of trials testing blood pressure management among nondialysis - dependent
CKD patients ( 15 924 total patients ) found more intensive therapies generally reduced mortality in all subgroups . -
pubmed
As a result of the unavailability of genetics , the
infection process of
R. - pubmed
distachyon provides a genetic resource that can confer
disease resistance against
R. - pubmed
We hypothesize that interventions increasing muscle strength might propagate to motor units at the abductor pharyngeal muscles , reducing collapsibility and , hence ,
sleep apnea severity in elderly
patients with
obstructive sleep apnea . -
pubmed
METHODS / DESIGN : This is a randomized clinical trial including
patients between 65 and 80 years of age , with
obstructive sleep apnea , and an
apnea - hypopnea index ( AHI ) between 20 and 50 events / hour , diagnosed by out - of - center in - home type III polysomnography . -
pubmed
METHODS : We retrospectively studied the outcomes of
patients who underwent RA at our institute for heavily calcified , balloon - uncrossable or - undilatable SB
lesions over an approximately 5 - year period ( January 2011 to September 2016 ) . -
pubmed
RESULTS : Two hundred and forty - four
patients underwent main vessel only
RA ( SB - MV +
RA group ) and another 48
patients underwent SB
RA ( SB + MV + - RA group ) for 49 side branches . -
pubmed
However ,
patients underwent SB
RA experienced more SB perforations and greater acute contrast - induced
nephropathy (
CIN ) . -
pubmed
Among the SB
RA patients , 30 ( 62.5 % ) underwent RA for both SB and MV ( SB + MV + RA subgroup ) , whereas the other 18 underwent SB only
RA ( SB + MV - RA subgroup ) . -
pubmed
CASE PRESENTATION : We describe the case of a 41/2 -year - old
boy not previously known to be a
diabetic who presented to the plastic surgery department for
gangrene of the left middle finger with surrounding
erythema and induration . -
pubmed
Effect of electron beam and gamma radiation on drug - susceptible and drug - resistant
Listeria monocytogenes strains in salmon under different temperature . -
pubmed
AIMS : To investigate the effect of gamma radiation and high energy electron beam doses on the inactivation of antibiotic - susceptible and antibiotic - resistant
Listeria monocytogenes strains inoculated on the surface of raw salmon fillets stored at different temperature ( -20 , 4 and 25 C ) . -
pubmed
Methods : The study group consists of 25
patients with nonhealing
corneal ulcers due to
herpes simplex or
herpes zoster infection and facial nerve or trigeminal nerve
paralysis as a result of a neurosurgical operation caused by a
tumour or
stroke . -
pubmed
Complete healing of the
ulceration was observed in 20
patients ( 80 % ) . -
pubmed
Four
patients ( 16 % ) experienced considerable improvement of their clinical condition ( reduced size and depth of the
ulceration and inflammatory state : smaller conjunctival injection and
swelling , improved visual acuity , and less subjective symptoms ) . -
pubmed
In all
patients , the progression of
corneal thinning was stopped . -
pubmed
Systemic
Toxicity of Smokeless
Tobacco Products in
Mice . -
pubmed
However , little is known about the systemic and
cardiovascular toxicity of smokeless
tobacco exposure . -
pubmed
Suppression of the circulating levels of immune cells upon exposure to smokeless
tobacco products may increase the susceptibility to
secondary infection . -
pubmed
The present study used functional magnetic resonance imaging to investigate the impact of life
trauma on basal
cortisol levels and neural responses to acute stress in 73 healthy
individuals during brief stress and neutral - relaxing imagery using a well - established , individualized imagery method . -
pubmed
BACKGROUND :
Seymour fractures are
distal phalanx fractures in
children with a juxta - epiphyseal pattern . -
pubmed
METHODS : We performed a retrospective study of
patients under 18 years old treated at a large pediatric hospital from 2009 to 2017 for an acute Seymour
fracture . -
pubmed
RESULTS : Mean age of
patients was 10 years , with 43 males and 22 females sustaining 65 Seymour
fractures . -
pubmed
Four
patients initially managed in the ED required an unplanned operation , usually because of
fracture redisplacement . -
pubmed
For
patients with
head and neck cancer requiring a maxillectomy , obturator prostheses help with quality of life . -
pubmed
Treatment sequelae can leave
patients with difficulty speaking and swallowing ,
reduced salivary function , reduction in maximal incisal opening , and at risk of
osteoradionecrosis . -
pubmed
Fifty - six percent are male , 85 % Caucasian , 30 % have a history of chronic
HCV and 71 % have compensated
cirrhosis . -
pubmed
Functional Subunit Reconstruction of Giant Facial
Congenital Melanocytic Nevi in
Children With the Use of Matriderm and Skin Graft : Surgical Experience and Literature Review . -
pubmed
Introduction : Facial giant
congenital melanocytic nevus represents a major
cosmetic deformity for the
child and parents and is a challenge for the plastic surgeons to achieve best cosmetic results . -
pubmed
Methods : An 8 - year - old
boy presented with a facial giant
congenital melanocytic nevus without leptomeningeal involvement . -
pubmed
The postoperative result was satisfactory with minimal residual
nevus around the eye , and the
patient was fully satisfied with the cosmetic and functional results . -
pubmed
A case of early
gastric cancer in a
patient with
splenic vein angioplany . -
pubmed
The aim of this study was to evaluate the
cytotoxicity , on
human chondrocytes , of
TXA at different concentrations and times of exposure and the mechanisms of cell
death . -
pubmed
OBJECTIVES : This systematic review and meta - analysis aimed to investigate the efficacy and safety of
VPA in
patients with
SMA . -
pubmed
METHODS : Eleven databases were systematically searched on 30 May 2017 for clinical trials that reported the efficacy and safety of
VPA in
SMA patients . -
pubmed
Tuberculosis caused by
Mycobacterium tuberculosis (
M. - pubmed
The key to reduce the spread and mortality rate of
tuberculosis is to develop faster and more sensitive approaches for detection of
M. - pubmed
[ Effects and mechanism of fecal transplantation on
acute lung injury induced by lipopolysaccharide in
rats ] . -
pubmed
LPS group and LPS+FMT group were intraperitoneally injected with LPS to generate
rat ALI model . -
pubmed
Calcium overload - induced
arrhythmia is suppressed by
farnesol in
rat heart . -
pubmed
Therefore , one can suggest that
azoramide , as a novel regulator , can provide direct cardioprotection in the IR - heart , at most , via affecting mitochondria and can be a good candidate as a new drug for the treatment of IR - associated
cardiovascular disorders in
mammalians with systemic IR . -
pubmed
Subtotal calvarial vault reconstruction utilizing a customized
polyetheretherketone (
PEEK ) implant with chimeric microvascular soft tissue coverage in a
patient with
syndrome of the trephined : A case report . -
pubmed
However , successful reconstruction may be difficult in
patients with complex and/or hostile
calvarial defects . -
pubmed
Based on our findings , we advocate delayed alloplastic implantation with total vascularized soft tissue coverage as a viable alternative for reconstructing extensive , hostile
calvarial defects in
patients with the
syndrome of the trephined . -
pubmed
OBJECTIVES : The present study evaluates the prognostic value of metabolic parameters related to the primary
tumor identifiedin preoperative
fluorodeoxyglucose (
FDG ) positron emission tomography ( PET)/computed tomography ( CT ) scans
inpatients with
endometrial cancer (
EC ) . -
pubmed
RESULTS : The study included 120
patients with
EC with a mean age of 62.3 + - 0.02 years . -
pubmed
Of the total , 32
patients diedaround the time of the analysis and 38
patients showed
disease progression . -
pubmed
No significant relationship was identified between the SUVmax , SUVmean , MTV , TLGvalues ,
patient age ,
tumor size , histology , grade and
MI degree , and OS or PFS . -
pubmed
Arterial reconstruction with donor iliac vessels during kidney transplantation in a
patient with severe
atherosclerosis . -
pubmed
Atherosclerosis is common in
patients with
end - stage renal disease . -
pubmed
Symptomatic improvement in
nasal obstruction was found to be consistently better in group A
patients at postoperative days 7 and 15 , but both groups achieved comparable symptom relief at the third month . -
pubmed
Oral Antiplatelet Drug Therapy on
Posterior Circulation Infarction in
Patients With Acute
Intracranial Atherosclerosis - Related
Vertebrobasilar Artery Occlusion . -
pubmed
This study compared recanalization rates , symptomatic
intracranial hemorrhage (
SICH ) , 90 day mortality , and functional outcomes between periprocedural
tirofiban and antiplatelet therapy in
patients with acute
intracranial atherosclerosis - related
vertebrobasilar artery occlusion . -
pubmed
Methods : A total of 105 consecutive
patients with acute
intracranial atherosclerosis - related
vertebrobasilar artery occlusion who underwent EVT +
tirofiban + oral antiplatelet or EVT + oral antiplatelet therapy at the Beijing Tiantan Hospital between January 2012 and July 2018 were included . -
pubmed
RT was interrupted / delayed in seven
patients ( 16 % ) for suspected
COVID-19 infection . -
pubmed
Previous coronavirus outbreaks such as
severe acute respiratory syndrome coronavirus can cause new - onset
diabetes mellitus (
DM ) . -
pubmed
This first - in -
human study evaluated
MEDI0562 in adultswith advanced
solid tumors . -
pubmed
EXPERIMENTAL DESIGN : In this phase I , multicenter , open - label , single - arm , dose - escalation ( 3 + 3 design ) study ,
patients received 0.03 , 0.1 , 0.3 , 1.0 , 3.0 , or 10 mg / kg MEDI0562 through intravenous infusion every 2 weeks , until confirmed
disease progression or unacceptable
toxicity . -
pubmed
Treatment - related adverse events ( TRAEs ) occurred in 67 % of
patients , most commonly
fatigue ( 31 % ) and infusion - related reactions ( 14 % ) . -
pubmed
Grade 3 TRAEs occurred in 14 % of
patients with no apparent dose relationship ; no TRAEs resulted in
death . -
pubmed
Data collected included
patient demographics , level of block , type and volume of local anesthetic , occurrence of pleural puncture , occurrence of
pneumothorax , evidence of
local anesthetic toxicity , and
patient vital signs . -
pubmed
Zero pleural punctures were identified during block performance ; however , two
patients were found to have a
pneumothorax on postoperative chest X - ray ( 3.6 per 1000 surgeries , 95 % CI 0.5 to 13.6 ; 0.9 per 1000 levels blocked , 95 % CI 0.1 to 3.3 ) . -
pubmed
Background : Monoclonal antibodies are a relatively new therapeutic option for
patients with severe refractory
asthma , which can be used as an add - on to maintenance therapy , reducing the need for systemic
corticosteroid usage , improving
asthma symptom control and reducing exacerbations . -
pubmed
We report a case of a
patient with severe refractory
eosinophilic asthma , reluctant to take systemic
steroids , who was successfully treated with
benralizumab alone during an acute
asthma attack . -
pubmed
Case presentation : A 59 - year - old Caucasian
woman with a history of
allergic asthma since childhood showed a progressive decline in lung function with difficult to control symptoms and an increased number of hospitalizations despite maximal maintenance treatment , and was diagnosed with severe refractory
asthma . -
pubmed
Sixty - one
patients were diagnosed with
NF and 28 with
SC . -
pubmed
The algorithm accurately diagnosed all 15
NF patients with a high ( > = 8) laboratory risk indicator for
necrotizing fasciitis (
LRINEC ) score . -
pubmed
This study aimed to investigate the prognostic role of circulating miR-146a in the prediction of early response to
imatinib treatment in
patients with
chronic myeloid leukemia (
CML ) . -
pubmed
Sixty
patients with
CML and 20 healthy controls were recruited in this study . -
pubmed
This study reported for the first time that measurement of the circulating miR-146a expression at 14 days can predict the early response to
imatinib treatment in
patients with
CML . -
pubmed
METHODS : Between January 2010 and December 2013 , 134
patients underwent arthroscopy and stabilization for recurrent
anterior dislocation of shoulder . -
pubmed
Out of total 40
patients in the curettage group , 6(15 % )
patients had
recurrence of
dislocation and none had subluxations , whereas in the non - curettage group 13(32.5 % )
patients had
recurrence of
dislocation and 3(7.5 % ) had subluxations . -
pubmed
Challenges with co - amplification of microbial DNA in interpretation of STR profiles obtained from
human skeletal remains . -
pubmed
TAK-242 ameliorates
olfactory dysfunction in a
mouse model of
allergic rhinitis by inhibiting neuroinflammation in the olfactory bulb . -
pubmed
OBJECTIVE :
Olfactory dysfunction (
OD ) is a common symptom of
allergic rhinitis (
AR ) that can seriously affect
patient quality of life ; however , the associated pathogenesis remains unclear . -
pubmed
Cisplatin is a widely used , highly effective antitumor drug , but some
patients have experienced irreversible
hearing loss as a result of its application . -
pubmed
Masked high
progesterone levels during in vitro fertilization and embryo transfer treatment in a
patient with
21 - hydroxylase deficiency : A case report . -
pubmed
Here , we report on an infertile
woman with
21OHD who initially showed normal
progesterone levels and spontaneous ovulation with the treatment by an endocrinologist . -
pubmed
The case underlines that close coordination is required between the endocrinologist and reproductive specialist for the total treatment for
woman with
21OHD . -
pubmed
Influence of the
cribriform degeneration (
cri ) mutation on
audiogenic seizures in DBA/2J
mice . -
pubmed
Effects of individual inhalation of aerosolized
amantadine hydrochloride in
mice infected with
influenza virus A / Bethesda 10/63 ( H2N2 ) and
A / Hong Kong 1 / 68 ( H3N2 ) . -
pubmed
Clinical and laboratory diagnosis of
enterotoxemia of
cattle . -
pubmed
Bone scans using
99mTc polyphosphate have been obtained in 174
patients with newly diagnosed
carcinoma of the breast . -
pubmed
In nine
patients , the roentgenograms were abnormal , but in 18 , there was scintiscan evidence of metastatic
disease involving bone , although one false - negative interpretation is included in this number . -
pubmed
In another eight
patients with normal or equivocal initial bone scintiscans ,
metastatic disease involving bone developed during a 12 months ' period of observation . -
pubmed
Spinal cord stimulation ( SCS ) of the low thoracic spinal epidural space was carried out in 11
patients with
pain from
peripheral arterial disease of the lower limbs . -
pubmed
Evidence of
rat stem cell engraftment ,
strain - specific transplantation tolerance , and skin - specific antigens . -
pubmed
This model for mixed xenogeneic chimerism with reliably detectable
rat lymphoid cells may provide a model to study the existence of tissue - specific
antigens across a
species barrier , as well as mechanisms responsible for the induction and maintenance of this
strain - specific transplantation tolerance . -
pubmed
Despite the not - inconsiderable financial , material and
human resources that have so far been made available -- mostly from outside the country -- only a small percentage of the presumptive number of
leprosy sufferers are receiving an adequate , modern combination therapy . -
pubmed
The influence of eye colour on susceptibility to
TTS in
humans . -
pubmed
In order to investigate the function of the inner ear melanin , noise - induced temporary
hearing loss ( temporary threshold shift , TTS ) was studied in
humans with either blue or brown iris colour . -
pubmed
Twenty - five
patients with
myocardial infarction were monitored in the acute phase and during follow - up with regard to the in vivo production of
prostacyclin (
PGI2 ) and
thromboxane (
TxA2 ) , by measurement of their major urinary metabolites ,
2,3 - dinor-6 - keto - PGF1 alpha and
2,3 - dinor - TxB2 , respectively . -
pubmed
In approximately 24 % of
patients the in vivo production of
prostacyclin did not increase during the acute phase of the
infarction process . -
pubmed
At the follow - up 2 years after the
myocardial infarction , eight cardiac events had occurred , all of which were noted among
patients who exhibited an expected increase in
prostacyclin production in association with the
infarction . -
pubmed
This would seem reasonable , since most of the
patients in this group had larger primary
infarctions . -
pubmed
The resultant
TCGF - activated EAL cells from
cancer patients significantly exceeded lytic activity of TCGF - activated
EAL cells from
patients with
liver cirrhosis for control ( p less than 0.01 ) . -
pubmed
Animals were sacrificed on Postoperative Days 1 , 2 , 4 , 7 , and 11 and the
wounds were studied . -
pubmed
We have studied the transport of ions in the small and large intestines of
CF patients . -
pubmed
A modification of Mason 's vertical banded gastroplasty for morbid
obesity is presented , along with experience from 62 treated
patients . -
pubmed
Subcutaneous
wound infection occurred in two
patients . -
pubmed
Three series of seven
hypertensive rats ( SHR ) were used . -
pubmed
Intranigral injection of
dynorphin-1 - 13 exerted a potent
seizure suppressant action in kindled
rats . -
pubmed
A 47 - year - old
man developed an acute
infectious mononucleosis - like illness with a moderate
lymphocytosis and numerous atypical lymphocytes in the peripheral blood . -
pubmed
Plasmodium falciparum : induction of resistance to
mefloquine in cloned
strains by continuous drug exposure in vitro . -
pubmed
Pets and
grass pollen allergenicity was more common among whites while
allergy to
Aspergillus fumigatus and
Ascaris lumbricoides was found more frequently among coloured patients . -
pubmed
Effect of lifetime administration of
dimethylaminoethanol on longevity , aging changes , and
cryptogenic neoplasms in
C3H mice . -
pubmed
The effects of lifetime treatment with
dimethylaminoethanol on longevity and
cryptogenic neoplasm formation were studied in females of two
mouse sub - lines , the C3H / HeN which carries a
germinal mammary tumor provirus and the C3H / HeJ(+ ) which also carries the exogenous
mammary tumor virus . -
pubmed
Among untreated C3H / HeJ(+ ) females , 89 % developed
neoplasms of the mammary gland , ovary , liver , lung and reticuloendothelial system , while the incidence was 88 % in the treated
mice . -
pubmed
In C3H / HeN females ,
neoplasms of the mammary gland , ovary , liver , lung and lymphatic system occurred in 57 % and in 60 % of treated
mice . -
pubmed
Also , there was no statistically significant difference between control and treated
animals in the age of onset or the type of specific
neoplasms . -
pubmed
Three
patients are presented as illustrative examples of severe
necrotizing pancreatitis associated with diuretic therapy . -
pubmed
Dose of
cat (
Felis domesticus ) allergen 1 ( Fel d 1 ) that induces
asthma . -
pubmed
All
patients developed
rhinitis and
asthma during exposure . -
pubmed
Five consecutive
patient groups undergoing coronary bypass surgery were studied for postoperative conduction disturbances and
atrial arrhythmias . -
pubmed
Aggregation and secretion of washed platelets from
stroke - prone spontaneously
hypertensive rats ( SHRSP ) were greatly reduced by the development of the
hypertension compared with those of platelets from age - matched normotensive Wistar - Kyoto
rats ( WKY ) . -
pubmed
Danazol has recently been reported to be an effective mode of treatment for
patients with refractory
immune thrombocytopenic purpura . -
pubmed
Posthypoglycemic
hyperglycemia in
diabetic children . -
pubmed
The occurrence of
SV40 - Neutralizing antibodies in sera of
patients with
genitourinary carcinoma . -
pubmed
Caloric regulation and food preference in normal ,
hyperphagic , and aphagic
rats . -
pubmed
[ Changes in the mean erythrocyte volume as an index of
water metabolism in
patients with
glaucoma ] . -
pubmed
In five
infants with
congenital defects of the brain and complete absence of temperature control there was no sweat response to thermal or direct chemical stimulation of the glands.6 . -
pubmed
Pharmacokinetics of
indocyanine green in
rats with
chronic renal failure . -
pubmed
Similarly , most
patients had long - lasting nasal airway improvement and reduction or elimination of recurring
sinusitis . -
pubmed
Although
aspirin sensitivity was associated with some of the more severe
asthmatic patients , it appeared not to be a factor in the responses to surgical treatment . -
pubmed
Four disclosant dyes were tested for antimicrobial activity against 27 oral reference
strains and five non - oral
human pathogens . -
pubmed
Methods of
mastitis control that are effective against
Streptococcus agalactiae and
Staphylococcus aureus have been developed and proven successful . -
pubmed
The total extent of their present involvement in
mastitis is not well documented , and this is due in part to differences in the nature of
infection by environmental pathogens compared to
Streptococcus agalactiae and
Staphylococcus aureus infections . -
pubmed
Hearing loss in
dogs after lesions of the brachium of the inferior colliculus and medial geniculate . -
pubmed
Bilateral section of the brachium of the inferior colliculus consistently resulted in an average
hearing loss of as much as 37 dB in the midrange of the
animals ' audiograms . -
pubmed
All
strains , with the exception of
M. - pubmed
Total
ischemia in
dog hearts , in vitro . -
pubmed
[ Effect of serum
glucose on the function of pancreatic exocrine in
diabetic rats ] . -
pubmed
These results indicated that
hyperglycemia might be one of the reasons which cause the dysfunction of pancreatic exocrine in
diabetic rats . -
pubmed
Peripheral giant cell granuloma : a clinical study of 77 cases from 62
patients , and literature review . -
pubmed
DESIGN : We reviewed retrospectively 77 cases of
PGCG from 62
patients , from our files with respect to incidence , sex ,
patient age , race , clinical
symptoms and signs , radiographic features and
recurrence following excision . -
pubmed
OBJECTIVE : The aim was to examine the effects of the
Na+/H+ exchange inhibitors
amiloride and
methylisobutyl amiloride (
MIA ) in buffer perfused
rabbit hearts subjected to one hour of normothermic
ischaemia ( 37 degrees C ) followed by reperfusion . -
pubmed
CONCLUSION : This study shows for the first time that both of the
Na+/H+ exchange inhibitors
amiloride and
MIA produce improved recovery of ventricular function in
rabbit hearts subjected to
ischaemia and reperfusion , although the beneficial effect was not obtained with drug administration at the time of reperfusion only . -
pubmed
Because of the risk that some
patients with
chronic neutropenia may have or develop
myelodysplasia and/or
leukemia , careful pretreatment evaluations ( blood , bone marrow and cytogenetics ) and long - term observations are extremely important . -
pubmed
An international registry for
patients with
SCN has been established to maintain records and further investigate these conditions . -
pubmed
In 115 predominantly
lithium - refractory
inpatients ,
neurologic findings were recorded , and blind raters assessed
valproate response from the medical record . -
pubmed
Patients with a
seizure history were much more likely to have a robust response to
valproate ( 70 % ) , when compared with
patients without such history ( 34.6 % ) . -
pubmed
History of
head injury and abnormal electroencephalographic findings also tended to be more common in those
patients with good response . -
pubmed
Overall , the group of
patients with any
neurologic abnormality exhibited a significantly higher rate of good response to
valproate ( 43.6 % ) than did the neurologically normal group ( 24.3 % ) . -
pubmed
Bipolar or
schizoaffective patients with abnormal neurologic features may represent a distinct subtype of illness and appear to be good candidates for
valproate therapy . -
pubmed
Adult spontaneously
hypertensive rats ( SHR ) and Wistar - Kyoto ( WKY )
rats were anesthetized with
halothane and artificially ventilated . -
pubmed
Cell extracts from a variety of cell lines , myeloid , T , B ,
mastocytoma , fibroblast ,
melanoma and
breast carcinoma of
human ,
mouse and
guinea pig promoted the growth of a wide variety of cell types , namely
human myeloid cells
HL-60 ,
human B cells
Daudi ,
human melanoma cells
A375 - C6 ,
mouse transformed - fibroblast cells
L929 ,
human myelomonocytic cells
THP-1 . -
pubmed
tuberculosis that is correlated with growth rate in
mouse spleen and lung tissue , to the avirulent
strain H37Ra by complementation . -
pubmed
tuberculosis
strain H37Rv was constructed and transformed into H37Ra . -
pubmed
In sixty
patients treated with
chloroquine (
Nivaquine ) 73 % showed
keratopathy . -
pubmed
The sequential changes of the activity of
peroxide metabolism enzymes and
thiobarbituric acid reaction substance ( TBARS ) as an indicator of lipid
peroxide concentration were observed to analyze the mechanisms of
tissue injury due to the administration of
paraquat in DDY
mice . -
pubmed
Tumor - cell DNA content predicts outcome in
children and
adolescents with clinical
group III embryonal rhabdomyosarcoma . -
pubmed
The Intergroup
Rhabdomyosarcoma Study Committee of the
Children 's Cancer Group and the Pediatric Oncology Group . -
pubmed
PURPOSE : The prognostic value of
tumor - cell DNA content ( ploidy ) was evaluated in
children with unresectable , nonmetastic
rhabdomyosarcoma of embryonal histology . -
pubmed
PATIENTS AND METHODS : Flow - cytometric techniques were used to estimate the ploidy of
tumor specimens from 34
patients with
embryonal rhabdomyosarcoma who were enrolled in the intergroup
rhabdomyosarcoma study III ( IRS III ) from 1985 to 1991 . -
pubmed
Significantly more
children with hyperdiploid
tumors achieved a complete response than did
children with diploid
tumors ( 85 % v 42 % ; P = .01 ) . -
pubmed
CONCLUSION :
Tumor - cell ploidy strongly correlates with outcome in
children with nonmetastic , unresectable
embryonal rhabdomyosarcoma . -
pubmed
In psychometric testing , there was no marked
depressive syndrome in the
HIV - positive
individuals , but a mild slowing of speed - dependent abilities . -
pubmed
It has been reported that
SCID (
severe combined immunodeficiency , scid / scid ) mice are more radiosensitive than normal
mice . -
pubmed
Furthermore , this less sensitive fraction might be a source of the " leaky " change of T and B cells , possibly due to the induction of an equivocal repair system which appears in the later stages of life in the
SCID mice . -
pubmed
These
patients represented 10 % of all
drug overdoses admitted over the same period . -
pubmed
An acute ( 48 - hr )
lethal toxicity study of
turbot at various stages from hatch to juveniles showed that prior to first exogenous feeding , larvae of
turbot were an order of magnitude more sensitive to cadmium toxicity than later developmental stages ( LC50 of 0.18 - 0.23 ppm
Cd versus 2 - 5 ppm
Cd ) . -
pubmed
[ Comparison of
retinal breaks between
patients with
atopic dermatitis and
mentally retarded patients with self - inflicted
ocular injury ] . -
pubmed
We compared the distribution of
retinal breaks in
retinal detachment between
patients with
atopic dermatitis (
AD ) and
mentally retarded patients who had self - inflicted
ocular injury (
MR ) . -
pubmed
The cases of
AD were 16 eyes in 14
patients ( six
males and eight
females , ranging in age from 15 to 52 years , mean 24.5 ) and the cases of
MR were 6 eyes in 5
patients ( 5
males , ranging in age from 14 to 25 years , mean 20.2 ) . -
pubmed
In the
patients with
AD , 14 ( 87.5 % ) of 16 eyes had
retinal breaks at the vitreous base , and 21 ( 87.5 % ) of 24
retinal breaks in 16 eyes were at the vitreous base . -
pubmed
In the
patients with
MR , five ( 83.3 % ) of 6 eyes had
retinal breaks at the vitreous base and 6(66.7 % ) of 9
retinal breaks in 6 eyes were at the vitreous base . -
pubmed
[ Effectiveness of mesoglycan therapy in
patients with
ischemia of the lower limbs . -
pubmed
METHODS : In the present investigation we studied the effect of mesoglycan in
patients with acute episodes of relative
lower limb ischemia ( Stage IIb according to Leriche - Fontaine classification ) coming to our observation . -
pubmed
RESULTS : From February 1995 thirty - six
patients , 24
males and 12
females , aged between 45 and 83 years ( mean + /- SD : 69.8 + /- 7.5 ) coming to our observation for acute relative
lower limb ischemia were enrolled . -
pubmed
At baseline , the diagnosis was Fontaine 's IIb stage ( walking distance & lt ; or = 200 m ) in all
patients , 17
patients presenting walking distance & lt ; 100 m. After 3 and 6 months of mesoglycan treatment a significant improvement of
symptoms and signs was observed in all
patients but one . -
pubmed
The administration of
mesoglycan was well tolerated , with only minor complaints in two
patients ( one case of
headache and one of
diarrhea ) . -
pubmed
CONCLUSIONS : The present preliminary results show that , in
patients with acute episodes of relative
lower limb ischemia , mesoglycan ( administered according to the described protocol ) is an effective and safe agent able to improve symptoms ( walking distance ,
pain , leg appearance ) and to possibly delay the need of surgical interventions . -
pubmed
In the investigation 43
patients with
type II diabetes mellitus and 33 normals were included . -
pubmed
[ Seroprevalence of the
infections caused by
Borrelia Burgdorferi and
Rickettsia Conorii in
humans and
dogs in primary health care of San Andreas del Rabanedo ( Leon , Spain ) ] . -
pubmed
BACKGROUND : Positive results in
infections of
borrelia burgdorferi and
Rickettsia conorii in
human and
canine population is studied in order to understand the situation of both in
humans , and at the same time discover the importance of the
dog as an indicator of these agents among those in the Health Area of San Andres del Rabanedo , Leon . -
pubmed
RESULTS : Positivity in both
infections was discovered in both
humans and
dogs . -
pubmed
We describe a case of multiple
lipoma of the tongue in a female
patient aged 60 years who also presented
subcutaneous cervical lipoma . -
pubmed
Twenty out of the 29
patients already showed a normal resorption half a year after the determination of the
resorption disorder , 5
patients after 1 year and 4
patients after 1 1/2 years . -
pubmed
Eleven or 14 of the 29
patients , respectively , with pathologically decreased
D - xylose resorption only had complaints of lower or upper gastrointestinal tract , respectively , and 10
patients did not have
abdominal complaints at all . -
pubmed
METHODS : We describe the case of a 76 - year - old
woman who came under our observation due to
stroke and
atrial arrhythmia . -
pubmed
METHODS : Four hundred and seventy - three
patients with
ankylosing spondylitis received placebo or active non - steroidal anti - inflammatory drug ( NSAID ) for 6 weeks , and changes between entry and completion were captured by BASDAI and the individual components . -
pubmed
Two
patients with
pulmonary vein tachycardias demonstrating atypical P - wave morphology were investigated . -
pubmed
One of the
patients had a
tachycardia with two different cycle lengths . -
pubmed
P - wave morphology was evaluated in 12 - lead ECGs from two
patients with incessant
atrial tachycardia , during
tachycardia and
sinus rhythm . -
pubmed
We hypothesize that dysfunction of homologous regions in the
human infant could lead to impaired ability to respond to
hypercapnia and could potentially be involved in the pathogenesis of
SIDS . -
pubmed
To investigate if these effects may be partly mediated by
histamine release ( HR ) we studied the influence of SP on HR from nasal mucosa of
subjects with and without
allergic rhinitis using an in vitro organ culture system . -
pubmed
SUBJECTS : Nasal mucosa of the inferior turbinate was obtained from ten
patients suffering from
allergic rhinitis and eighteen non - allergic
subjects receiving surgical therapy for
nasal obstruction . -
pubmed
Visualization of
rat pial microcirculation using the novel orthogonal polarized spectral ( OPS ) imaging after
brain injury . -
pubmed
Because receptors and cytokine ligands that mediate
metastasis formation are sparsely expressed in the adult healthy
organism and are more readily reached by pharmaceuticals than intracellular drug targets they may represent a particularly suitable focus for therapeutic intervention . -
pubmed
OBJECTIVES : The purpose of the study was to assess the long - term outcome of
patients with small
ventricular septal defects (
VSDs ) considered not to require surgical closure during childhood . -
pubmed
BACKGROUND : Although patients with small
VSDs have generally been considered not to require surgery , more recent data suggest that a significant percentage of these
patients develop serious problems during adult life . -
pubmed
METHODS : A total of 229 consecutive
patients ( 115
females ) with a VSD considered too small to require surgery during childhood as defined by normal pulmonary artery pressure , less than 50 % shunt , pulmonary vascular resistance & lt ; or = 200 dynes x s cm(-5 ) , no VSD - related
aortic regurgitation (
AR ) , and no symptoms and who had no additional hemodynamically relevant
heart defect were followed in an adult
congenital heart disease program . -
pubmed
For 118
patients who entered the study between 1993 and 1996 and were prospectively followed for 7.4 + /- 1.2 years , event - free survival with end points defined as
death ,
endocarditis or heart surgery was 99.1 + /- 0.8 % at three years , 96.5 + /- 1.7 % at six years and 95.5 + /- 1.9 % at eight years . -
pubmed
CONCLUSIONS : Outcome in well - selected
patients with a small
VSD is good . -
pubmed
METHODS AND RESULTS : Thirteen
patients developed
myocardial ischemic injury within 2 weeks of cardiac transplantation (
ischemia group ) . -
pubmed
These were compared with 10 transplantation
patients who had no evidence of
ischemia ( control group ) . -
pubmed
One in four
children affected by parental
substance abuse . -
pubmed
BACKGROUND : We have previously demonstrated in a
rodent model the differential effects that specific intraluminal nutrients exert on gut
ischemia / reperfusion ( I / R )
injury . -
pubmed
Direct detection of
enterovirus 71 (
EV71 ) in clinical specimens from a
hand , foot , and mouth disease outbreak in Singapore by reverse transcription - PCR with universal enterovirus and
EV71 - specific primers . -
pubmed
BACKGROUND :
Hazelnuts are a common cause of
food allergy . -
pubmed
Allergic reactions to
hazelnuts range from
oral allergy syndrome caused by cross - reactivity between tree pollen and
hazelnut proteins to severe
anaphylactic reactions . -
pubmed
OBJECTIVE : The aim of the study was to identify these pollen - independent allergens in
patients with
hazelnut allergy with systemic reactions . -
pubmed
Prevalence of
sleep - disordered breathing and continuous positive airway pressure compliance : results in chinese
patients with first - ever
ischemic stroke . -
pubmed
MEASUREMENTS AND RESULTS : We recruited 23
women and 28
men , who were admitted to the hospital within 4 days of
stroke onset , with a mean ( + /- SD ) age of 64.2 + /- 13.0 years and a
body mass index (
BMI ) of 24.3 + /- 4.4 kg / m(2 ) for this study . -
pubmed
Twenty - seven
patients ( 53 % ) and 9
patients ( 17.6 % ) , respectively , reported a history of snoring and severe
daytime sleepiness prior to experiencing a
stroke , while the mean Epworth
sleepiness scale score was 6.8 + /- 3.6 . -
pubmed
Polysomnography revealed 34
patients ( 67 % ) with an
apnea -
hypopnea index ( AHI ) of & gt ; or = 10 events per hour , 31
patients ( 61 % ) with an AHI of & gt ; or = 15 events per hour , and 25
patients ( 49 % ) with an AHI of & gt ; or = 20 events per hour . -
pubmed
Significant obstructive
SDB , defined as an AHI of & gt ; or = 20 / h , was more prevalent in
ischemic stroke patients than in control subjects ( 49 % vs 24 % , respectively ; p = 0.04 ) and was associated with a higher
BMI ( p = 0.046 ) . -
pubmed
A subgroup of 20
patients not receiving CPAP showed partial spontaneous improvement of
SDB at 1 month ( baseline AHI , 32.3 + /- 17.6 events per hour ; AHI at 1 month , 23.0 + /- 18.8 events per hour ; p = 0.01 ) with a trend toward improvement for the obstructive but no significant change for the central events , whereas no improvement in AHI was noted for the four
patients receiving CPAP . -
pubmed
Impact of non - axillary sentinel node biopsy on staging and treatment of
breast cancer patients . -
pubmed
A total of 549
breast cancer patients underwent lymphoscintigraphy after intratumoural injection of
( 99m ) Tc - nanocolloid . -
pubmed
Internal mammary
metastases were found in seventeen
patients and
metastases in other non - axillary sentinel nodes in ten
patients . -
pubmed
A small proportion of clinically node negative
breast cancer patients can be staged more precisely by biopsy of sentinel nodes outside level I and II of the axilla , resulting in additional decision criteria for postoperative regional or systemic therapy . -
pubmed
Hepatic arterial infusion using
pirarubicin combined with systemic chemotherapy : a phase II study in
patients with nonresectable
liver metastases from
colorectal cancer . -
pubmed
PATIENTS AND METHODS : From December 1991 to April 1994 , 75
patients with unresectable
colorectal metastases confined to the liver were included in this multicenter study to receive intra - arterial hepatic
pirarubicin and a systemic monthly regimen of
5 - fluorouracil ( 5 - FU ) and
folinic acid . -
pubmed
RESULTS : Tolerance of this regimen was rather good ; however , functional catheter problems were observed in 29
patients ( 45 % ) resulting in failure of HAI in 21 cases ( 33 % ) after a median of three cycles ;
vomiting grade 3 was present in 12.5 % of
patients ,
neutropenia grade 4 in 23 % and
alopecia grade 3 in 19 % . -
pubmed
[ TREATMENT OF
PATIENTS WITH
RHEUMATOID ARTHRITIS WITH AN EXTRACT OF
BETA - HEMOLYTIC STREPTOCOCCI ] . -
pubmed
A total of 428
patients with
insomnia aged 55 years and older received placebo ( 2 weeks ) , prolonged release
melatonin 2 mg ( 3 weeks ) and then placebo ( 2 weeks ) . -
pubmed
We present a case of an adult
patient with
truncus arteriosus communis and
secondary pulmonary hypertension . -
pubmed
Multidirectional voluntary glenohumeral dislocation in a 7 - year - old
patient : a case report . -
pubmed
SCN goitrogenic effects occur secondary to
iodine deficiency in special circumstances of high consumption of incomplete detoxified
cassava and insufficient protein intake . -
pubmed
Potential applications include detection of coronary in - stent
thrombosis or
thrombus burden in
patients with
acute coronary syndromes . -
pubmed
OBJECTIVE : To compare effectiveness of oral therapy with reduced
nicotinamide adenine dinucleotide (
NADH ) to conventional modalities of treatment in
patients with
chronic fatigue syndrome (
CFS ) . -
pubmed
METHODS : A total of 31
patients fulfilling the Centers for Disease Control criteria for
CFS , were randomly assigned to either
NADH or nutritional supplements and psychological therapy for 24 months . -
pubmed
Chemotherapy alone vs. chemotherapy plus high dose multiple antioxidants in
patients with advanced
non small cell lung cancer . -
pubmed
OBJECTIVE : To describe the unique nursing responsibilities involved in providing nursing care to severely obese
weight loss surgery patients and to develop evidence - based guidelines for safe
patient care . -
pubmed
BACKGROUND : The uptake of
omega-3 polyunsaturated fatty acids (
PUFAs ) into the liver , gut mucosa , and
tumor tissue and plasma levels after preoperative administration of supplemented enteral nutrition was investigated in
patients with
malignancies of the upper gastrointestinal tract . -
pubmed
CONCLUSIONS : This study suggests that administration of
PUFA - enriched diets leads to increased incorporation of
EPA and
DHA not only in liver and gut mucosa tissue , but also in
tumor tissue in
patients with solid
gastrointestinal tumors . -
pubmed
Patient outcomes are improved when prolonged periods on dialysis and the complications of systemic
oxalosis have not occurred . -
pubmed
We evaluated the feasibility and efficacy of the emerging ' real - time three - dimensional transthoracic echocardiography ' technique for comprehensive assessment of cardiac anatomy , physiology , pathomorphology and pathophysiology in
patients with
structural heart disease . -
pubmed
METHODS AND RESULTS :
Patients with
structural heart disease ( n=152 ) were evaluated by conventional two - dimensional transthoracic echocardiography and real - time three - dimensional transthoracic echocardiography using standard protocol . -
pubmed
A total of 38
congenital heart disease patients were examined including 23
patients with
atrial septal defect . -
pubmed
To address this issue , appropriate
animal models frequently clarify the etiology and pathogenesis of
autoimmune diseases , although no single
animal model perfectly mimics a
human disease . -
pubmed
Transgenic and knock out
mice have advanced the investigation of
cutaneous LE . -
pubmed
Sevoflurane pretreatment inhibits endotoxin - induced
shock in
rats . -
pubmed
Sequence analysis of full - length
HBV genome showed more substitutions in X , rt , and surface proteins in patients with
SHE than in those without elevated
HBV DNA level . -
pubmed
We undertook a retrospective chart review during a 24 - month period of
patients treated at an outpatient
burn center . -
pubmed
The medical records of
patients with
neuropathic - like pain complaints , including the sensation of pins and needles , burning , stabbing , shooting , or " electric " sensations , were included for analysis . -
pubmed
Predictors for complications after loop stoma closure in
patients with rectal
cancer . -
pubmed
PURPOSE : This unmatched case control study was undertaken to evaluate factors contributing to surgery - related complications of loop stoma closure in
patients with
rectal cancer . -
pubmed
CONCLUSIONS : The present study in a homogeneous group of
patients with rectal
cancer as elective indication for temporary loop stoma construction confirms the high complications rate and mortality rate associated with stoma closure . -
pubmed
RESULTS : Peripheral blood
eosinophilia was observed in the ' ig ' and ' ig / in'-NRL - sensitized
animals in comparison to normal controls ( p & lt ; 0.05 ) . -
pubmed
Increased
airway hyperreactivity was found in ' ig'-NRL - sensitized -
mice ( 15.1 + /- 2.5 vs. 8.9 + /- 1.7 cm
H2O x ml(-1 ) x s , p & lt ; 0.05 ) . -
pubmed
CONCLUSION : The option of
LPV / r monotherapy as maintenance therapy in
HIV - infected patients following induction of virological response with triple therapy including
LPV / r might be a more efficient alternative than maintaining triple therapy , as evidenced by a more favorable cost - efficacy ratio . -
pubmed
Four months after the treatment the
patient presented no symptoms and
GP did not recur . -
pubmed
PURPOSE :
Axonal damage and loss of neurons correlate with permanent
vision loss and
neurologic disability in
patients with
optic neuritis and
multiple sclerosis (
MS ) . -
pubmed
METHODS : Experimental
autoimmune encephalomyelitis (
EAE ) , an
animal model of
MS , was induced by immunization with proteolipid protein peptide in SJL / J
mice . -
pubmed
OBJECTIVE : In this work , we analyzed the vertical transmission of
dengue virus in
Aedes aegypti mosquitoes collected in two endemic localities in the state of Oaxaca , Mexico . -
pubmed
Additional studies are needed to clarify the relationship between the two epidemics so that effective interventions can be developed to improve the health and lives of
children with both
asthma and
obesity . -
pubmed
Acute lupus pneumonitis in an 11 - year - old
girl with
lupus nephritis is reported . -
pubmed
METHODS : In this cross - sectional case - control study 313 unrelated
Caucasians ( Slovene population ) with
type 2 diabetes mellitus were enrolled : 206
patients with
PDR and the control group of 107
subjects with
type 2 diabetes of duration of more than 10 years who had no clinical signs of
diabetic retinopathy . -
pubmed
A 64 - year - old
woman with intermittent
vaginal bleeding was referred under the clinical impression of
cervical cancer . -
pubmed
The prognosis of
patients with pericardial and abdominal wall
metastases from recurrent
cervical cancer is usually poor because of the systemic dissemination of the disease . -
pubmed
PATIENTS : Forty - one adult
patients diagnosed with
otitis media with
effusion were recruited into the trial and underwent grommet insertion under local anesthesia ; 21 were randomly allocated to the
EMLA group and 20 to the Ametop group . -
pubmed
MAIN OUTCOME MEASURES : The primary outcome measure of the study was the level of
pain experienced by the
patient . -
pubmed
[ The formation of
infliximab and anti -
infliximab immune complexes as an explanation for non - responding to
infliximab treatment of
rheumatoid arthritis : observational study in 4
patients ] . -
pubmed
OBJECTIVE : To investigate the in vivo mechanism of non - responding to
infliximab treatment of
patients with
rheumatoid arthritis (
RA ) and the role of anti -
infliximab antibodies by using radiolabeled
infliximab . -
pubmed
METHOD : Two responding and two non - responding
RA patients were infused with radiolabeled
infliximab . -
pubmed
Biomechanical testing was performed on
pig thoracic spines instrumented with 7 - segment anterior
scoliosis constructs . -
pubmed
We report a
patient with cervical
nerve root compression operated by anterior transdiscal approach with plate and bone graft . -
pubmed
Helium breathing provides modest antiinflammatory , but no endothelial protection against
ischemia - reperfusion injury in
humans in vivo . -
pubmed
We hypothesized that inhalation of
helium provides protection against postocclusive
endothelial dysfunction after
ischemia - reperfusion of the forearm in
humans . -
pubmed
Each
volunteer was randomly exposed to 15 min of
forearm ischemia in the presence or absence of
helium inhalation . -
pubmed
The tests allowed to determine the boundary values of the growth inhibition zones and the minimum inhibitory concentrations of the antibiotics for susceptible and resistant
strains of
B. - pubmed
Nutrient media and reference
strains for testing antibiotic susceptibility of
B. - pubmed
METHODS : Records of 19
men and 11
women aged 9 to 34 ( mean , 17 ) years with
osteosarcoma around the knee joint were reviewed . -
pubmed
RESULTS : In all
patients , the first symptom was
pain , which was more pronounced on weight bearing in 16 ( 53 % ) of them and was worse at night in 11 ( 37 % ) . -
pubmed
Swelling was noticed in 28
patients ( a mean of 7 weeks after
pain onset ) . -
pubmed
The mean interval from presentation to radiography was 3 ( range , 0 - 20 ) weeks ; in 8
patients this interval exceeded 3 weeks despite a noticeable
swelling . -
pubmed
There has been a recent focus on the presence of nerve fibers in the eutopic endometrium of
patients with
endometriosis . -
pubmed
STUDY DESIGN : Cross - sectional study of computed tomographic scans of the temporal bones in
patients with no
congenital abnormalities . -
pubmed
SUMMARY A fast - neutron mutagenized population of
rice seedlings was screened with
Magnaporthe grisea , the causal agent of
rice blast disease , to identify mutants with alterations in the defence response . -
pubmed
The fourth mutant line , ncr1 (
necrosis in
rice ) , has an
LM phenotype under all conditions tested and lacks enhanced resistance to either
M. - pubmed
It has been shown previously that treating an
animal with
N - acetyl - L - cysteine (
NAC ) , a scavenger of free radicals , significantly minimizes hypoxic - ischemic - induced
brain injury in various acute models . -
pubmed
Using a subacute
swine model of neonatal
hypoxia - reoxygenation ( H - R ) , we evaluated the long - term beneficial effect of
NAC against oxidative stress - induced
brain injury . -
pubmed
Serotonin syndrome in an orthopaedic
patient secondary to
linezolid therapy for
MRSA infection . -
pubmed
A 67 - year - old patient was admitted for incision and drainage of a recurrent
methicillin - resistant
Staphylococcus aureus (
MRSA )
hip abscess . -
pubmed
Between 2004 and 2009 , 60
patients with proximal
tibial fractures were included in this prospective study . -
pubmed
There was one case of lateral joint collapse ( & gt;10 ) in a
patient with open bicondylar plateau
fracture . -
pubmed
RATIONALE : Mortality is exceedingly high and rapid among patients infected with
HIV and
tuberculosis (
TB ) , in part because of limited access to appropriate
TB diagnostics . -
pubmed
The microscopic observation drug - susceptibility (
MODS ) assay is a simple , rapid , low - cost test for
TB and multidrug - resistant ( MDR )
TB , but data in individuals infected with
HIV and in Africa are limited . -
pubmed
MODS test performance did not differ by patients '
HIV status ( sensitivity 88 % vs. 90 % , specificity 97 % vs. 100 % for
HIV - positive versus
HIV - negative , respectively ) . -
pubmed
CONCLUSIONS : Among adult
TB suspects predominantly infected with
HIV ,
MODS provided high sensitivity and specificity for rapid diagnosis of
TB and
MDR - TB . -
pubmed
It is also a testicular germ cell
tumor susceptibility factor in
mice . -
pubmed
Normalized coagulation markers and anticoagulation proteins in
children with severe
beta - thalassemia disease after stem cell transplantation . -
pubmed
The hypercoagulable state is well recognized in
patients with severe
beta - thalassemia disease . -
pubmed
METHODS : Data were obtained retrospectively from
patients with massive
suprachoroidal hemorrhage who were treated in Worthing and Southlands National Health Service Trust between January 2003 and December 2008 . -
pubmed
All
patients underwent early controlled drainage of massive
suprachoroidal hemorrhage using 100 %
perfluoropropane as a
tamponade . -
pubmed
The remaining three
patients had poor visual outcome because of
retinal detachment with
proliferative vitreoretinopathy . -
pubmed
The most common risk factor in this case series was
glaucoma , which was seen in five
patients . -
pubmed
Arteriosclerosis was the only risk factor in two
patients . -
pubmed
For
patients admitted to medical units , optimal management of
delirium includes reassessment of medications ,
pain , sleep , nutrition , mobility , need for physical restraints , and bowel and bladder function . -
pubmed
Multicomponent interventions performed by the hospital care team that address risk factors can prevent
delirium in
patients in medical units and those undergoing
hip fracture repair . -
pubmed
This includes attention to the depth of sedation during spinal anesthesia and the addition of regional nerve blocks to
patient - controlled analgesia in orthopedic
patients , both of which may reduce
postoperative delirium . -
pubmed
METHODS AND FINDINGS : 95
patients were included , and they were divided into three groups with different
burn area : group I ( n = 33 ) , group II ( n = 32 ) and group III ( n = 30 ) . -
pubmed
According to whether there was development of
MODS or not ,
patients were divided into
MODS group ( n = 28 ) and none -
MODS group ( n = 67 ) ; then the
patients with
MODS were further divided into non - survivor group ( n = 17 ) and survivor group ( n = 11 ) . -
pubmed
The similar results were found in
MODS patients and the non - survivor group as compared with those without
MODS and the survival group on days 3 - 21 postburn ( P<0.05 or P<0.01 ) . -
pubmed
RESULT : The primary features of these
patients were prolonged high - grade
fever ( 50/50 ) ,
hepatomegaly ( 44/50 ) ,
splenomegaly ( 38/50 ) ,
hemocytopenia ( 47/50 ) ,
hyperferritinemia ( 49/50 ) ,
coagulopathy ( 44/50 ) ,
hemophagocytosis in
bone marrow ( 42/50 ) ,
liver dysfunction ( 42/50 ) and
hypertriglyceridemia ( 42/50 ) . -
pubmed
Newcastle disease virus : a promising agent for
tumour immunotherapy . -
pubmed
Malignant tumours are a major cause of mortality in
humans . -
pubmed
Currently used therapeutic regimens have not improved survival rates of
patients suffering from
malignant tumours much because of their limited efficacy and side - effects . -
pubmed
A therapeutic approach that uses
Newcastle disease virus (
NDV ) represents an attractive new tool for
tumour immunotherapy . -
pubmed
Significant evidence exists regarding the oncolytic effects of
NDV , suggesting its potential use in the treatment of various
tumours . -
pubmed
Furthermore , clinical trials have suggested that several
NDV strains have the potential for
cancer virotherapy with few side - effects compared with traditional treatments . -
pubmed
Apoptosis following
NDV infection may contribute to the observed oncolytic effects ; however ,
NDV could also stimulate both innate and adaptive antitumour immune responses . -
pubmed
For many years , different approaches have been investigated ( or are in the process of being developed ) regarding the use of
NDV for the treatment of
malignancies . -
pubmed
Recent advances using reverse genetics have provided a means of generating recombinant
NDV strains with improved oncolytic and immune regulatory properties . -
pubmed
CONCLUSIONS / SIGNIFICANCE : The
human vaginal bacterial biota is heterogeneous and marked by greater species richness and diversity in women with
BV ; no species is universally present . -
pubmed
The incidence of this disorder is probably less than 1 % in
patients with mild
hypertension , but rises to as high as 10 to 40 % in
patients with acute , severe or refractory
hypertension . -
pubmed
Atherosclerotic lesions are present in almost 7 % of adults older than 65 years and up to 50 % of
patients presenting with diffuse
atherosclerotic disease . -
pubmed
Pharmacological therapy in
patients diagnosed with
Peyronie ' s disease . -
pubmed
The combination between oral therapy and intralesional agents can improve the quality of life of the
patients with
Peyronie ' s disease . -
pubmed
We present two cases of self - inflicted urethrovesical
foreign body in
children . -
pubmed
Foreign bodies are rarely found in the lower urinary tract of
children . -
pubmed
INTRODUCTION : The aim of this study was to investigate the intraoperative findings ,
postoperative complications , donor site morbidity and
patients ' Quality of Life in order to evaluate the usefulness of the free osteofasciocutaneous fibula flap in the reconstruction or construction of a mandibula , neophallus , lower leg or forearm . -
pubmed
The larger size of this
rat model as compared with the
ALS mice , will facilitate studies involving manipulations of spinal fluid and the spinal cord . -
pubmed
The effectiveness of ridetherapy in
children with
benign joint hypermobility syndrome during articulatory changes in the knee joint . -
pubmed
It has been established that in
children with
benign joint hypermobility syndrome during articulatory changes in the knee the use of ridetherapy provides an increase in muscle strength , to a certain degree their
hypertrophy , the development of joint - muscular perception , the increase of proprioreception , the minimizing of
excessive joint movement , the antinociceptive effect and the avoidance of secondary developed complications . -
pubmed
The identified
strain SHSY of
S. - pubmed
Paclitaxel is a widely used chemotherapy drug for advanced
laryngeal cancer patients . -
pubmed
However , the fact that there are 20 - 40 % of advanced
laryngeal cancer patients do not response to
paclitaxel makes it necessary to figure out potential biomarkers for
paclitaxel sensitivity prediction . -
pubmed
Collectively , our study might provide potential biomarkers for
paclitaxel sensitivity prediction and drug resistance targets in
laryngeal cancer patients . -
pubmed
Use of
ticagrelor in
patients with ST - elevation
myocardial infarction undergoing thrombolysis . -
pubmed
PURPOSE : The aim of the present study was to test the hypotheses that a greater oxidative capacity in
children results in a lower
phosphocreatine (
PCr ) depletion , a faster
PCr resynthesis and a lower
muscle acidification during high - intensity intermittent exercise compared to adults . -
pubmed
CONCLUSIONS : From our results we suggest relatively higher rates of oxidative
ATP formation in
children 's muscle for covering the
ATP demand of high - intensity intermittent exercise compared to adults , enabling children to begin each exercise interval with significantly higher
PCr concentrations and leading to an overall lower
muscle acidification . -
pubmed
Split cord malformation types I and II : a personal series of 131
patients . -
pubmed
PURPOSE : A personal series of 131
patients with
split cord malformation (
SCM ) operated on is presented . -
pubmed
The ages of
patients with
neurological deficits and
orthopedic deformities were significantly older than those without deficits ( P = 0.030 ) . -
pubmed
The duration of symptoms was longer in the
patients with
neurological deficits and
orthopedic deformities than that in those without deficits ( P = 0.00095 ) . -
pubmed
In six
patients , composite
SCMs were present . -
pubmed
Only one
patient with a
type II SCM did not have an associated
spinal cord lesion . -
pubmed
A
type I SCM was more frequently encountered in
patients with
spina bifida ( P & lt ; 0.0005 ) . -
pubmed
Transient
postoperative complications were seen in 29
patients ( 22 % ) . -
pubmed
Retethered cord syndrome developed in five
patients with a
type I SCM . -
pubmed
CONCLUSIONS : The risk of
neurological and orthopedic deficits increases with the age of the
patient . -
pubmed
All
patients should be surgically treated when diagnosed , especially before the development of orthopedic and
neurological manifestations , and all associated lesions should also be treated at the same session . -
pubmed
Aflp analysis of
xanthomonas axonopodis and x. Arboricola
strains used in xanthan production studies reveal high levels of polymorphism . -
pubmed
Amplified fragment length polymorphism ( AFLP ) was used to analyze the genetic diversity of 14
strains of
Xanthomonas arboricola pv . - pubmed
pruni and seven
strains of
X. - pubmed
All 14
pathovar pruni strains were included in a single main group ( SD = 0.58 ) , while the
pathovar phaseoli strains were divided into three separate groups , with one group containing five
strains ( SD = 0.38 ) and two isolated groups ( SD = 0.31 and 0.27 ) composed of only one
strain each . -
pubmed
For the unique
strain without xanthan production capacity (
X. - pubmed
In two
patients , satisfaction was low due to residual
loss of flexion as a result of
osteoarthritis and
cold intolerance in another . -
pubmed
Altered pharmacokinetics of
piperacillin in
febrile neutropenic patients with
hematological malignancy . -
pubmed
This study assessed the pharmacokinetics and dosing adequacy of
piperacillin in
febrile neutropenic patients after the first dose . -
pubmed
Chemotherapy research highly prioritizes overcoming the multidrug resistance ( MDR ) in
human tumors . -
pubmed
MATERIALS AND METHODS : In this case - control study , 20 infertile
POR patients and 20 normal
women took part in this study and underwent controlled ovarian stimulation . -
pubmed
This review summarizes recent key findings on
human and
mouse monocyte subpopulations , specifically highlighting their phenotype , functional characteristics and mechanisms of recruitment at homeostatic conditions , in
atherosclerotic vascular disease , and after
acute myocardial infarction . -
pubmed
OBJECTIVE : To present our experience regarding transumbilical single - incision laparoscopic heminephroureterectomy ( SILH ) in
children with
duplex kidney anomalies , and to investigate its feasibility and safety compared with those of conventional laparoscopic heminephroureterectomy ( CLH ) . -
pubmed
PURPOSE : To review bicycle and motorcycle wheel spoke
injuries around the foot and ankle in 24
children . -
pubmed
METHODS : Medical records of 12
boys and 12
girls aged 2 to 11 ( mean , 5.3 ) years who presented with an isolated
posterior heel injury caused by wheel spokes of a motorcycle ( n=9 ) or bicycle ( n=15 ) were reviewed . -
pubmed
RESULTS : All 9
motorcycle injury patients and 8 of 15
bicycle injury patients had
lacerations . -
pubmed
The remaining 7
bicycle injury patients had
abrasions and developed
skin necrosis and
ulcerations , with 5 requiring debridement . -
pubmed
Seven
patients with severe
skin loss required skin grafting or flap surgery for
wound coverage . -
pubmed
Studies in
human SK - N - SH neuroblastoma cells revealed that
CM572 induced an immediate dose - dependent increase in cytosolic
calcium concentration . -
pubmed
The
cytotoxic activity of
CM572 was selective for
cancer cells over normal cells , being much less potent against primary
human melanocytes and
human mammary epithelial cells . -
pubmed
Mechanisms of
acute toxicity are likely conserved across
invertebrate , aquatic , and
mammalian species , suggesting that dose - response concordance would be high and in vitro mechanistic data could predict responses in multiple species under conditions of similar bioavailability . -
pubmed
We tested this hypothesis by comparing
acute toxicity between
rat ,
daphnia , and
fish and by comparing their respective acute data to inhibition of mitochondria membrane potential ( MMP ) using U.S. Environmental Protection Agency ToxCast in vitro high - throughput screening data . -
pubmed
Logarithmic scatter plots of
acute toxicity data showed a clear relationship between fish , daphnia , and intravenous
rat but not oral
rat data . -
pubmed
No samples from the
patients with secondary
MN and other
glomerulonephritis or healthy controls were positive with the ELISA test . -
pubmed
Adult
patients undergoing gross total resection of
intracranial atypical meningioma are eligible . -
pubmed
Patients with multiple
meningioma , optic nerve sheath
meningioma , previous
intracranial tumour , previous cranial radiotherapy and
neurofibromatosis will be excluded . -
pubmed
METHODS : Nineteen
adolescents on average 7.5 months post -
mTBI completed neuropsychological testing and an fMRI auditory - verbal N - back working memory task . -
pubmed
The comparison group included 19 healthy
controls matched to the
mTBI group for demographic variables and N - back task performance . -
pubmed
Effects of Interscalene Nerve Block for Postoperative
Pain Management in
Patients after Shoulder Surgery . -
pubmed
Patients ' characteristics , preoperative shoulder score and range of motion , surgical and anesthetic condition in addition to visual analog scale ( VAS )
pain score , postoperative PCA consumption , and adverse outcomes were evaluated . -
pubmed
In this study , we report a biological screening of 38 chemically characterized
terpenes from different classes , which have a
hydroxyl group connected by hydrophobic chain or an acceptor site , against the blood fluke
Schistosoma mansoni , the parasite responsible for
schistosomiasis mansoni . -
pubmed
Confocal laser scanning microscopy revealed that compound 10 induced severe
tegumental damage in adult
schistosomes and a correlation between viability and tegumental changes was observed . -
pubmed
Loss of T Follicular Helper Cells in the Peripheral Blood of
Patients with
Chronic Graft - versus - Host Disease . -
pubmed
In contrast to
mouse models , where an enhanced frequency of splenic TFH cells contributes to
cGVHD , patients with
cGVHD showed significantly depleted circulating TFH cells after both UCB and MRD transplantation . -
pubmed
METHODS : A retrospective analysis of a prospectively entered database was performed for all
patients who underwent
lung cancer resection from January 2012 to June 2014 . -
pubmed
RESULTS : Of 315
patients with primary
lung cancer , 55.6 % were female and the mean age was 70 + - 9.6 years . -
pubmed
Preoperative brain MRI detected asymptomatic
metastases in four of 315
patients ( 1.3 % ) . -
pubmed
At a median postoperative follow - up of 19 months ( range 6 - 43 ) , symptomatic
brain metastases developed in seven additional
patients . -
pubmed
The objectives of this study were to determine the effect of the dry
cow management system ( pasture or confined ) on : ( 1 ) lying behaviour and activity ; ( 2 ) feeding and heat stress behaviours ; ( 3 )
intramammary infections , postpartum . -
pubmed
BACKGROUND :
Testicular cancer is one of the most common and most treatable
cancers in
men aged 15 - 49 years . -
pubmed
AIMS : This article aims to offer a complete and concise overview of
cognitive dysfunction and quality of life for
patients with
testicular cancer . -
pubmed
Immune responses to polyclonal T - cell vaccination in
patients with progressive
multiple sclerosis . -
pubmed
To explore this , in this study , 39
patients with progressive ( chronic )
multiple sclerosis (
MS ) were multiply immunized with autological polyclonal T - cell vaccines ( TCVs ) . -
pubmed
T - Cell vaccination had no significant effects on T - cell sub - population contents in the blood of
MS patients after 2 years of immunotherapy initiation . -
pubmed
Collectively , the results suggest that polyclonal T - cell vaccination is safe to use , able to induce measurable , long - lasting , anti - inflammatory immune effects in
patients with advanced
MS . -
pubmed
We present the complete and annotated genome sequence of
strain Szeged of
PCV1 , determined by Pacific Biosciences RSII long - read sequencing platform . -
pubmed
The objective of this study was to evaluate the utility of exercise testing in asymptomatic
patients with
type 1 Brugada pattern to prognosticate major
arrhythmic events ( MAE ) during follow - up . -
pubmed
METHODS AND RESULTS : Treadmill exercise testing was conducted for 75 asymptomatic
patients with
type 1 Brugada pattern and for 88 healthy control subjects . -
pubmed
KEY RESULTS : 56 EGJOO , 40
HE patients and 33 controls were identified . -
pubmed
Platelet counts had a nadir at day 3 followed by a rebound
thrombocytosis at day 21 , with nadir values significantly lower in septic
patients . -
pubmed
METHODS : Tissue samples were collected from 136
patients with
ocular venous malformation . -
pubmed
A total of 124
patients had no complication up to 2 years after LDLT , and 74
patients had complications including
biliary stricture and graft rejection . -
pubmed
Adjuvant therapy is rarely used because there is no evidence to distinguish
patients with high
recurrence risk . -
pubmed
The median follow - up was 71months ( range : 12months-143months ) , 129
patients ( 25.5 % ) experienced
recurrence with median
disease - free survival ( mDFS ) of 19months . -
pubmed
Lung lobe torsion in seven juvenile
dogs . -
pubmed
CASE DESCRIPTION 7 juvenile ( & lt ; 12 months old )
dogs with
lung lobe torsion were evaluated . -
pubmed
A CBC showed
leukocytosis and
neutrophilia in all
dogs . -
pubmed
Anemia was present in 6
dogs , 2 of which received packed RBC transfusions . -
pubmed
Clinicians should be aware of the possibility of
lung lobe torsion when evaluating young
dogs with clinical signs related to the respiratory system , including those with vague signs , to avoid undue delays in treatment . -
pubmed
A 73 - year - old
man presented with three episodes of
dysphasia and disinhibited behaviour , a single
seizure and transient
ischaemic attack - like events characterised by right arm and/or leg
weakness . -
pubmed
Repeated cerebrospinal fluid examination showed a persistent
lymphocytosis with mildly reduced
glucose and elevated protein ; oligoclonal bands and
viral PCR were negative . -
pubmed
The leading cause of
hyponatremia in
patients with
cancer is
syndrome of inappropriate antidiuretic hormone secretion (
SIADH ) ; this oncologic emergency requires immediate intervention . -
pubmed
Out of 110
patients , 13
patients ( 11.8 % ) required colectomy for technical failure ( 7
patients ) or
carcinoma ( 6
patients ) . -
pubmed
During a median follow - up of 16 months ( range 6 - 41 months ) , 2
patients had
adenoma recurrence . -
pubmed
CONCLUSIONS : Advanced endoscopic surgery appears to be a safe and effective alternative to colectomy for
patients with complex premalignant
lesions deemed unresectable with conventional endoscopic techniques . -
pubmed
A 35 - year - old
woman presented with a three - month history of left groin and thigh
pain . -
pubmed
Case presentation : We report the case of a
patient with full thickness
burns on both legs , leading to the exposure of joints of the right ankle and the right foot and left patellar tendon . -
pubmed
We used
C57BL / 6 mice infected by Plasmodium berghei ANKA ( PbA - infected
mice ) , a well - known
murine model of severe
malaria . -
pubmed
Proteolysis in
septic shock patients : plasma peptidomic patterns are associated with mortality . -
pubmed
We investigated in
humans the relationship between
septic shock , proteolysis , and outcome . -
pubmed
METHODS : Intensive care
patients with
septic shock ( n=29 ) or
sepsis ( n=6 ) and non - hospitalised subjects ( n=9 ) were recruited as part of the prospective observational trial ' ShockOmics ' ( ClinicalTrials.gov Identifier NCT02141607 ) . -
pubmed
RESULTS : Evidence of systemic proteolysis was indicated by a larger number of circulating peptides in
septic shock patients , compared with septic
patients and non - hospitalised healthy subjects . -
pubmed
The peptide count and abundance in the
septic shock patients were greater in
patients who died ( n=6 ) than in survivors ( n=23 ) , suggesting an association between magnitude of proteolysis and outcome . -
pubmed
Plasma peptidomics is proposed as a new tool to monitor clinical trajectory in
septic shock patients . -
pubmed
BACKGROUND : Limited data are available regarding the characteristics and prognosis of
patients with
stroke due to
varicella zoster virus ( VZV ) vasculopathy . -
pubmed
METHODS : We studied 4
patients ( 2
men and 2
women ; age , 38 - 63 years ) from a single center who developed acute
ischemic stroke due to
VZV vasculopathy . -
pubmed
Each
patient had a characteristic
skin rash prior to
stroke , with the interval from
rash to
stroke onset ranging from 13 to 122 days . -
pubmed
Two
patients experienced antecedent
cranial nerve palsies ; one had the third , seventh , ninth , and 10th nerve
palsies and the other had the fourth nerve
palsy before
stroke . -
pubmed
Intracranial arterial stenosis was only identified in one
patient on magnetic resonance angiography . -
pubmed
As a result of combined therapies with
acyclovir ,
steroid , and antithrombotic agents , neurological symptoms markedly improved in 3
patients , whereas 1
patient was left with moderate
hemiplegia . -
pubmed
CONCLUSIONS :
Cranial nerve palsies may be
prodromal symptoms of
VZV - associated
stroke . -
pubmed
METHODS : Three hundred nine postmenopausal female
patients with
osteoporotic vertebral compression fractures were included in the study . -
pubmed
Recurrent
infections with this bacterium are common , suggesting that
S. - pubmed
Using an ex vivo
infection model of primary
human monocyte - derived dendritic cells , we found that
S. - pubmed
Although all purified leukocidins could kill DCs ,
infections with live bacteria revealed that
S. - pubmed
Herein , we describe the successful management of a
patient with an otherwise inoperable , ruptured aortic root
pseudoaneurysm using combined cardioaortic replacement under hypothermic circulatory arrest . -
pubmed
A blend of dietary
lovastatin and
delta - tocotrienol , each at no - effect doses , suppress the growth of implanted
murine B16 melanomas in
C57BL6 mice . -
pubmed
Effects of electroacupuncture on
anxiety and
depression in unmarried
patients with
polycystic ovarian syndrome : secondary analysis of a pilot randomised controlled trial . -
pubmed
OBJECTIVE : To evaluate the efficacy of electroacupuncture ( EA ) for the treatment of
anxiety and
depression in unmarried
patients with
polycystic ovarian syndrome (
PCOS ) by secondary analysis of a randomised controlled trial . -
pubmed
METHODS : A prospective pilot randomised controlled trial of unmarried
women with
PCOS was conducted from November 2012 to March 2016 . -
pubmed
CONCLUSION : EA appears to improve symptoms of
anxiety /
depression and quality of life in
PCOS patients and may influence serum levels of NE and 5 - HT . -
pubmed
Zone Formation of Lymphocyte Infiltration at the Invasive Front Results in the Prolonged Survival of
Individuals With Endometrial Serous
Carcinoma and Endometrioid
Carcinoma With Serous Component . -
pubmed
RESULTS : Out of a total of 51
patients , 38 cases had weak
LI and 13 had strong LI . -
pubmed
The progression - free survival of
patients with weak
LI was worse ( p=0.02 ) . -
pubmed
To demonstrate the feasibility of robotic middle ear access in a clinical setting , nine adult
patients with severe - to - profound
hearing loss indicated for cochlear implantation were included in this clinical trial . -
pubmed
Erratum : Cumulative radiation exposure from imaging procedures and associated lifetime
cancer risk for
patients with
lymphoma . -
pubmed
Finally , subcutaneous xenotransplanted
tumor models of
HCT116 cells were established in
BALB / c nude mice . -
pubmed
Since insufficient sources of transplantable liver and possible immune rejection severely hinder the wide application of conventional liver transplantation therapy , artificial three - dimensional ( 3D ) liver culture and assembly from stem cells have become a new hope for
patients with
end - stage liver diseases , such as
cirrhosis and
liver cancer . -
pubmed
Long - term remissions of young
patients with high - risk
follicular lymphoma after first - line autologous stem cell transplantation : Three case reports . -
pubmed
PATIENT CONCERNS : 3 young - adult
patients with
FL received ASCT as first - line treatment . -
pubmed
DIAGNOSIS : All the 3
patients were no more than 30 years old and the diagnosis of
FL was confirmed by histopathological and immunohistochemical evaluations . -
pubmed
OUTCOMES : All the 3
patients got complete remission and
minimal residual disease negativity after ASCT , The median follow - up time was 109 ( 97 - 117 ) months , and all of them were in remission more than 8 years after transplant . -
pubmed
LESSONS : Guidelines for FL are mainly based on elderly
patients , but are not suitable enough for all , especially for the young
FL patients . -
pubmed
Nowadays , the pathogenesis of
minimal change disease (
MCD ) is still not well - known , and the current understanding on
MCD is mainly based on data derived from
children , and very few adults . -
pubmed
The results showed that in
patients at the onset of
MCD , the ratio and activation of basophils were all higher than those of healthy controls ( all P < .05 ) . -
pubmed
In vitro test results showed that basophils from healthy controls can be activated by the serum taken from
patients with
MCD . -
pubmed
Among 62
patients at the onset of
MCD , with complete remission after treatment and 1 year of follow - up , the relative and absolute basophil counts before treatment were higher in the long - term remission group ( n = 33 ) than that of the
relapse group ( n = 29 ) . -
pubmed
Hyperoxia in
patients with
cardiogenic shock after
myocardial infarction supported with venoarterial extracorporeal membrane oxygenation . -
pubmed
BACKGROUND : Venoarterial extracorporeal membrane oxygenation ( V - A ECMO ) improves perfusion and oxygenation in
patients with
cardiogenic shock . -
pubmed
Recent evidence suggests
hyperoxia may be harmful , particularly in
critically ill patients . -
pubmed
The aim of this study was to describe
oxygen exposure in
patients receiving V - A ECMO after acute
myocardial infarction and to investigate the association between
hyperoxia and in - hospital mortality . -
pubmed
We compared the mean and peak arterial
oxygen tensions over the first 72 h after V - A ECMO initiation ( n = 30 ) with those from a convenience sample of
patients treated with an intra - aortic balloon pump ( IABP ) ( n = 30 ) for
cardiogenic shock . -
pubmed
Patients on V - A ECMO had significantly higher arterial
oxygen tensions during the first three days than those with an IABP , at 0 - 24 h ; V - A ECMO : 286.51 mmHg ( 135.76 ) vs IABP : 103.48 mmHg ( 15.22 ) , p < 0.01.Thirteen of 30 ( 44.8 % )
patients in the V - A ECMO cohort manifested extreme
hyperoxia ( PaO2 > = 300 mmHg ) in the first 24 hrs , compared with none in the IABP population . -
pubmed
CONCLUSION : Severe
hyperoxia is common in
patients receiving V - A ECMO after acute
myocardial infarction , and this continues for at least 72 h. We found no association between extreme
hyperoxia and clinical outcomes . -
pubmed
Return to driving is a better predictor of
patient outcome than return to work after
aneurysmal subarachnoid hemorrhage . -
pubmed
OBJECTIVE : Return to work and driving are major rehabilitation goals for
patients after an
aneurysmal subarachnoid hemorrhage (
aSAH ) . -
pubmed
METHODS : Medical records of
patients with
aSAH were retrospectively reviewed from 2010 - 2018 . -
pubmed
Septicaemia of subterranean termites
Coptotermes curvignathus caused by disturbance of bacteria isolated from termite gut and its foraging pathways . -
pubmed
METHODS :
Mothers ( N = 181 ) were assessed periodically , beginning at 16 weeks ' gestation , using the Center for Epidemiologic Studies -
Depression Scale . -
pubmed
CONCLUSIONS : Although the expansion of the North American Contact
Dermatitis Group standard screening series has decreased the yield from the
AVC series from 21.1 % to 13.9 % , it still remains a useful adjunct for
patients suspected of having cosmetics or disinfectants
allergy . -
pubmed
BACKGROUND : This retrospective study was conducted to know clinical and radiographic outcomes , complication rate , and survival of THA in
patients with high
hip dislocation secondary to
developmental dysplasia(
DDH ) or
septic arthritis of the hip(
SSH ) . -
pubmed
METHODS : Between March 2005 and September 2014 , there were consecutive series of 53 THAs in
patients with a highly dislocated hip secondary to
DDH or
SSH . -
pubmed
Two
patients developed proximal humerus
fractures , of which 1 had osseous changes through which the
fracture occurred . -
pubmed
Our findings show these
AAV - XV variants are highly efficient at cell transduction at low dose and demonstrates the importance of the AAP coding region in both viral particle assembly and cell
infection . -
pubmed
By virtue of neutralizing antibodies against AAV that impede
patient repeat - dosing , the dose of AAV for in vivo gene delivery has been high , which has resulted in unfortunate recent safety concerns and
deaths in
patients given higher - dose AAV gene therapy . -
pubmed
Impact of statin on long - term outcome among
patients with
end - stage renal disease with
acute myocardial infarction (
AMI ): a nationwide case - control study . -
pubmed
However , in
patients with
end - stage renal disease (
ESRD ) , the protective effects of statin are controversial . -
pubmed
To evaluate the impact of chronic statin use on clinical outcomes of
patients with
acute myocardial infarction (
AMI ) with
ESRD . -
pubmed
We compared the effects of statin use in term of all - cause
death among
patients with
AMI with
ESRD . -
pubmed
RESULTS : Statin use resulted in a significantly higher survival rate in
patients ith
AMI with
ESRD compared with non - statin users . -
pubmed
After adjusted the comorbidities the male
patients and
patients with
DM ,
PVD ,
HF and
CVA had lower long - term survival rate ( all p<0.001 ) . -
pubmed
Patients with
AMI with
ESRD on
statin therapy exhibited a significantly lower risk of mortality compared with non - statin users ( p<0.0001 ) . -
pubmed
CONCLUSION : Among
patients with
ESRD with
AMI , statin therapy was associated with reduced all - cause mortality . -
pubmed
Though most
patients with renal involvement linked to
antineutrophil cytoplasmic antibodies associated vasculitis (
AAV ) have
pauci - immune glomerulonephritis , only a few patients were identified to have atypical renal pathology . -
pubmed
Echothiophate cataracts in
monkeys . -
pubmed
coli
UTI than screening for antibodies against the selected uropathogenic
E. - pubmed
The pharmacokinetic disposition of
prednisolone was studied following oral administration ( 10 mg ) to eight
patients with untreated
coeliac disease of mild or moderate severity , seven coeliac
patients on a strict gluten - free diet and ten normal subjects . -
pubmed
A representative sample of 95 hospitalized
bipolar manic - depressive patients was followed up from 1959 to 1975 . -
pubmed
In 525 operations on the heart and major vessels
neurologic complications were noted in 47
patients . -
pubmed
Lordosis behaviour in male , female and androgenized female
rats . -
pubmed
The transfer of
deuterium from
[ 1 R-2H ] ethanol and
[ 1 S-2H ]- ethanol to reduced metabolites of administered compounds was measured in female
rats provided with bile
fistulas . -
pubmed
Aldosterone and
corticosterone production in renal
hypertensive rats . -
pubmed
The development of
hypertension , which had been elicited by clamping one renal artery in the presence of an untouched contralateral kidney , has been pursued in
rats for up to six weeks after operation , and
aldosterone and
corticosterone production was studied at various intervals . -
pubmed
Ovulation induction with a single - blind treatment regimen comparing
naltrexone , placebo and
clomiphene citrate in
women with
secondary amenorrhea . -
pubmed
A single - blind ovulation induction protocol comparing
naltrexone , placebo and
clomiphene citrate was evaluated in eight
patients with
secondary amenorrhea . -
pubmed
Extension of these findings to disease - related immunogens may yield effective antigen - specific treatments of
human allergy and
autoimmune diseases . -
pubmed
Polyvalent antibodies to
S typhi were demonstrated in 28/30 ( 93 % )
typhoid patients , 0/11 bacteremic
patients (
E coli or
S paratyphi A ) and 0/15 asymptomatic individuals . -
pubmed
Typhoid patients tested on admission or at discharge showed similar high reactivity rates to ELISA . -
pubmed
Lithium ion does not protect brain against transient
ischemia in
gerbils . -
pubmed
We examined the effects of
lithium chloride on the morphologic outcome after 5 minutes of
cerebral ischemia induced in
gerbils by occluding both common carotid arteries under brief
halothane anesthesia . -
pubmed
Subgingival microbiota in
squirrel monkeys with naturally occurring
periodontal diseases . -
pubmed
To evaluate the effects of late thrombolysis on left ventricular volume and function in
acute myocardial infarction , two - dimensional echocardiography and radionuclide angiography were performed before discharge and after 1 year of follow - up study in 34
patients with acute
anterior myocardial infarction . -
pubmed
A 65 - year - old
man had painless progressive
proptosis of five years ' duration in his left eye . -
pubmed
Symptoms of
oestrogen deficiency in
women with
oestradiol implants . -
pubmed
Intestinal microflora of the newborn
rat as related to mammary , faecal , and vaginal Staphylococci
strains isolated from the dam . -
pubmed
To determine the relative importance of maternal microflora ( faeces , vagina , and teats ) in the contamination of newborn
rats ,
strains of staphylococci from six different families ( dam + litter ) were isolated . -
pubmed
The staphylococci
strains found in the gut of the newborn
rat originated first from the teats and thereafter from the faeces . -
pubmed
The IG
lymphoma encompassed a heterogeneous group of
patients with varying prognoses but the overall survival curve was indistinguishable from that of HG
lymphoma . -
pubmed
Mild
anemia was common and occurred in 40 - 50 % of the
patients . -
pubmed
In conclusion , the characteristic features of
NHL in Taiwan include : ( 1 ) a high proportion of HG
lymphoma and low proportions of
LG and
follicular lymphomas ; ( 2 ) a heterogeneous
patient composition of IG
lymphoma with an unfavorable overall prognosis. -
pubmed
In approximately 80 % of
patients with scirrhous
carcinoma of the stomach ,
recurrence of
cancers occurs even after potentially curative resection , and
recurrence most frequently occurs in the form of peritoneal
metastasis . -
pubmed
We performed intraoperative peritoneal cytology on
patients with scirrhous
carcinoma of the stomach . -
pubmed
Free
cancer cells were demonstrated in the Douglas cavity in 16 of 32 ( 50 % )
patients who underwent potentially curative gastrectomy . -
pubmed
The postoperative 5 - year survival rate was 23 % in
patients without detectable free
cancer cells in the peritoneal cavity , compared with only 9 % in
patients with microscopic evidence of intraperitoneal free
cancer cells . -
pubmed
Therefore , we have applied hyperthermic continuous peritoneal perfusion ( CHPP ) on
patients with scirrhous
carcinoma of the stomach in order to develop a surgical adjuvant therapy effective for the prevention of
recurrence of peritoneal involvement . -
pubmed
These
animals were hemodynamically evaluated at 3 to 6 months after operation and found to have no resting gradients or any degree of
aortic regurgitation . -
pubmed
Involvement of opioid and other systems in
ethanol abstinence
audiogenic seizures in the
rat ? -
pubmed
We have studied 42 subjects , including 6 healthy controls , 6 ileal resection subjects , 15
ulcerative colitis patients , and 15
patients with unresected ileal
Crohn ' s disease . -
pubmed
[
Osteomyelitis caused by
Pasteurella multocida following
dog bite . -
pubmed
Although the causes of essential
hypertension remain obscure , 2 different mechanisms for long - term vasoconstriction that sustain diastolic
hypertension in the experimental and clinical forms of
primary aldosteronism and
renovascular hypertension can also be identified and quantified among
patients with essential
hypertension . -
pubmed
Depending on the state of
sodium balance , these 2 mechanisms contribute reciprocally to maintenance of arteriolar tone in experimental models , in both normal and
hypertensive people , and in
patients with
congestive heart failure . -
pubmed
In vivo
genotoxicity of
nitrates and
nitrites in germ cells of male
mice . -
pubmed
Effects of both
sodium nitrate ( doses of 600 and 1200 mg / kg / day for 3 days ) and
sodium nitrite ( doses of 60 and 120 mg / kg / day for 3 days ) on spermatids of
mice were investigated by measuring unscheduled DNA synthesis ( UDS ) 17 days after the end of treatment , and
sperm - head abnormality 11 and 17 days after the end of treatment . -
pubmed
Total mixed diets were 40 %
corn silage ( DM basis ) , 15 %
alfalfa hay , and 45 % concentrate mix . -
pubmed
[ T and B lymphocyte function of
patients with infectious complications after surgery for
congenital heart defects ] . -
pubmed
The parameters of T- and B - lymphocyte system were studied in 65
patients with
congenital heart defects aged from 2 to 31 years with infectious complications after operation . -
pubmed
We encountered eight
patients with
epidermolysis bullosa (
EB ) simplex of the
Dowling - Meara type , who presented in infancy with severe
blistering and were originally clinically thought to have recessive dystrophic
EB . -
pubmed
However , in two of the three older
patients , the development of severe disabling
hyperkeratosis of the palms and soles has been a prominent feature . -
pubmed
The correct diagnosis of
EB simplex was initially not made in five
patients , because , on routine histologic examination , the
blister was apparently subepidermal . -
pubmed
Three
subjects with
Graves ' disease , three with
toxic multinodular goitre and three with
euthyroid multinodular goitre were sampled every hour for 24 h. The results obtained were compared to those from five euthyroid control subjects . -
pubmed
The same
tumor size dependence was found for the relative Tumak uptake in the other
mouse organs studied ( e.g. -
pubmed
Polychlorinated biphenyl- and
triphenyl - induced
gastric mucosal hyperplasia in
primates . -
pubmed
Polychlorinated biphenyl or
triphenyl ingestion by
subhuman primates for 3 months produced
hyperplasia and
dysplasia of the gastric mucosa . -
pubmed
A small intranuclear virus recovered from lymphatic tissue of a
bovine with
malignant lymphoma . -
pubmed
Induction of
embryonic death in
sheep by intrauterine injection of a small volume of normal saline . -
pubmed
Methylmalonic aciduria and
vitamin B12 deficiency in the
rat . -
pubmed
Disorders of serum protein catabolism in
patients with tubular
proteinuria , the
nephrotic syndrome , or
uremia . -
pubmed
The present study was directed toward determining the role of the kidney in the metabolism of various classes of serum proteins and to define the urinary protein excretion patterns and the pathogenesis of
disorders of protein metabolism in
patients with
proteinuria . -
pubmed
Three distinct
disorders of protein metabolism were noted in
patients with
renal tubular disease and tubular
proteinuria ,
glomerular disease ( the
nephrotic syndrome ) , and disease involving the entire nephrons (
uremia ) , respectively . -
pubmed
Relationships between
headache and
amine changes after administration of
reserpine to
migrainous patients . -
pubmed
[ Some data on the role of
serotonin and
acetylcholine in the pathogenesis of
cardiac arrhythmia in
children ] . -
pubmed
Efficacy of
desipramine in endogenomorphically
depressed patients . -
pubmed
This study was designed to test the hypothesis that there are 2 biochemical subgroups of ' endogenously '
depressed patients --
serotonin - deficient and
noradrenalin - deficient groups -- which respond differently to antidepressants depending on relative blockade of
serotonin vs.
norepinephrine ( NE ) reuptake . -
pubmed
Patients with pervasive
anhedonia and autonomy of
depressed mood (
endogenomorphic depressives ) were treated first with the noradrenergic agent
desipramine (
DMI ) , then , if still
depressed , such
patients were randomized double - blind to continued
DMI or
clomipramine (
CMI ) , a primarily serotonergic agent . -
pubmed
Of 34 such endogenomorphically
depressed patients 2 responded during a placebo period and 5 dropped out . -
pubmed
Eleven of the endogenomorphically
depressed patients also met Research Diagnostic Criteria for situational
depression ( reactive ) . -
pubmed
Effects of
hypoxia on the kinetic and morphological characteristics of
human melanoma cells grown as colonies in semi - solid agar medium . -
pubmed
An investigation was made of the cell populations that occur in the sequential strata of
human melanoma (
MM96 ) colonies . -
pubmed
Studies conducted in our laboratory relating to the development of immune processes in
B vitamin deficiency states of experimental
animals have been reviewed . -
pubmed
To study the clinical and physiologic manifestations of the
grain fever syndrome and the potentially pathogenic role of complement activation , 12 subjects ( six
grain workers and six healthy non - grain
workers ) underwent inhalation provocations with airborne grain dust . -
pubmed
Fever developed in four grain
workers and two controls . -
pubmed
Leukocytosis , ranging between 11,700 and 24,300 leukocytes / mm3 with left shift , developed in five grain
workers and five controls . -
pubmed
Relationship of exercise capacity to resting left ventricular performance and basal plasma
norepinephrine levels in
patients with
congestive heart failure . -
pubmed
Seventeen
patients with chronic
congestive heart failure (
CHF ) were studied to assess the relationship of resting left ventricular function , as measured by noninvasive and invasive methods , to maximal exercise capacity , as measured by peak total body
oxygen consumption ( VO2 ) . -
pubmed
Supine basal plasma
norepinephrine ( NE ) was also measured to evaluate its relationship to the severity of
heart failure and to determine whether it may be a better predictor of exercise capacity in
patients with
CHF than the more commonly employed noninvasive and invasive tests of left ventricular function . -
pubmed
The supine basal plasma NE , which was elevated in these 17
patients ( 612 + /- 100 pg / ml ) , had an inverse relationship with
stroke work index ( r - -0.70 , p less than 0.01 ) and
stroke index ( r = -0.83 , p less than 0.001 ) and a positive correlation with right atrial pressure ( r = 0.81 , p less than 0.001 ) . -
pubmed
Influence of
15 retinoic acid amides on
urinary bladder carcinogenesis in the
mouse . -
pubmed
A series of experiments was conducted to determine the efficacy of 15 synthetic
retinoic acid amides (
retinamides ) as inhibitors of chemical
carcinogenesis of the urinary bladder in
C57BL / 6 x DBA / 2F1 mice . -
pubmed
An analysis of the features of lower
respiratory diseases (
LRD ) associated with
Respiratory Syncytial Virus (
RSV ) in 21
children aged 1 - 23 months , indicated that the clinical features did not differ appreciably from those described for
LRD due to other infective agents . -
pubmed
Streptococcus pneumonia and
Klebsiella pneumoniae respectively , were isolated from blood culture in the two cases with lobar
pneumonia alone . -
pubmed
The results of complex diagnosis and treatment in 237
patients with
obstructive cholangitis are discussed . -
pubmed
Steady - state pharmacokinetics of
cyclosporine in renal transplant
patients : does an influence of age or
body weight exist ? -
pubmed
Distal accentuation of conduction slowing distinguished these
patients from those with
Charcot - Marie - Tooth polyneuropathy type 1A ,
chronic inflammatory polyneuropathy , and from controls , as demonstrated by regression of distal motor latency on proximal conduction velocity . -
pubmed
These results give a clear rationale for the use of in vitro expanded TIL from
NSCLC in protocols of adoptive immunotherapy in
patients with residual disease following surgery . -
pubmed
Acute
toxicity of
deltamethrin and
dieldrin to
Oreochromis niloticus ( LIN ) . -
pubmed
GABA and
phosphatidylserine in
human photosensitivity : a pilot study . -
pubmed
Previous experimental studies have shown that the simultaneous administration of
gamma - aminobutyric acid (
GABA ) and
phosphatidylserine (
PS ) can exert an anticonvulsant activity in different
seizure models ; moreover , a preliminary trial showed some effect of the association
GABA - PS in
patients with
absence seizures . -
pubmed
The aim of this study was to investigate the antiepileptic properties of
GABA - PS in the model of
human photosensitivity . -
pubmed
Nine
patients with
epilepsy associated with an EEG pattern of
photoconvulsive response at intermittent photic stimulation entered a 3 - day study . -
pubmed
These results indicate that a single acute administration of
GABA - PS has no effect in the
human photosensitivity model , and suggest that the efficacy of
GABA - PS in
human epilepsy , as shown by a preliminary investigation , may possibly require chronic administration . -
pubmed
[ Detection of mycobacterial DNA by in vitro enzymatic amplification in
lung nodular lesions in a
patient with
ovarian immature teratoma ] . -
pubmed
Platinum - based chemotherapy is still the cornerstone in the chemotherapeutic approach of
ovarian cancer patients . -
pubmed
Hormonal therapy continues to be an important component of treatment of
patients with advanced or recurrent
endometrial cancer . -
pubmed
Peripheral blasts recovered from
patients with
acute myelogenous leukaemia (
AML ) were efficiently lysed by
interleukin-2 ( IL-2 )- activated heterologous natural killer ( NK ) cells in vitro . -
pubmed
OBJECTIVE -- To analyse the natural history of
progressive supranuclear palsy (
PSP or
Steele - Richardson - Olszewski syndrome ) and clinical predictors of survival in 24
patients with
PSP confirmed by necropsy , who fulfilled the NINDS criteria for a neuropathological diagnosis of typical
PSP . -
pubmed
The
patients ' mean age at onset of
PSP was 63 ( range 45 - 73 ) years . -
pubmed
RESULTS -- The most frequent clinical features ( occurring in at least 75 % of the
patients ) were early
postural instability and
falls ,
vertical supranuclear palsy ,
akinetic - rigid predominant parkinsonian disorder characterised by symmetric
bradykinesia and axial
rigidity unrelieved by
levodopa ,
pseudobulbar palsy , and frontal release signs . -
pubmed
Fractures occurred in 25 % of the
patients but were unrelated to the severity of the gait or to the presence of falls . -
pubmed
Onset of falls during the first year are emphasised , as they could lead to an early diagnosis and influence the prognosis of
patients with
PSP . -
pubmed
Whether appropriate treatment of the
dysphagia could prolong the survival of
PSP patients needs to be explored . -
pubmed
Six adult female
patients ( mean age , 41 yr ) with
Nelson ' s syndrome were studied . -
pubmed
A 36 - year - old
man with a history of
hypertrophic obstructive cardiomyopathy presented to the emergency room with " stabbing "
chest pain . -
pubmed
In
patients with such ascending testes , an abnormal development or accidental
trauma of the genitofemoral nerve may be involved in testicular ascent . -
pubmed
[
Gastric antral vascular ectasia (
GAVE ) in a
patient with
primary biliary cirrhosis : seven - year follow - up ] . -
pubmed
The complex manifests very much higher toxicity ( 200 - 1400 times ) against
human tumor cells (
CEM ,
MCF-7 ,
HepG2 ) in vitro and surpasses
TCDD in selectivity . -
pubmed
Prediction of outcome in intensive care unit
trauma patients : a multicenter study of Acute Physiology and Chronic Health Evaluation ( APACHE ) , Trauma and Injury Severity Score ( TRISS ) , and a 24 - hour intensive care unit ( ICU ) point system . -
pubmed
OBJECTIVE : To conduct a multicenter study to validate the accuracy of the Acute Physiology and Chronic Health Evaluation ( APACHE ) II system , APACHE III system , Trauma and Injury Severity Score ( TRISS ) methodology , and a 24 - hour intensive care unit ( ICU ) point system for prediction of mortality in ICU
trauma patient admissions . -
pubmed
Lamivudine therapy of
hepatitis B virus - related
liver disease :
cirrhosis , posttransplantation
recurrence , and de novo
infection . -
pubmed
In contrast , in the recently published OASIS-2 study , outcome in
patients with
unstable angina pectoris was significantly better with hirudin than with
heparin . -
pubmed
BACKGROUND :
Cytarabine is an essential drug for inducing remission of
acute myelogenous leukemia , and it is also one the most effective drugs used as salvage therapy for
patients with all types of relapsed
acute leukemia . -
pubmed
Nevertheless , there is considerable room for improvement in the treatment of
patients with
relapsed leukemia in terms of both the reinduction rate and the duration of response . -
pubmed
METHODS : Fifty - five
adults with relapsed or refractory
acute leukemia or the blastic phase of
chronic myelogenous leukemia (
CML ) received salvage therapy with the FLAM regimen , which consisted of
fludarabine ,
cytarabine , and increasing doses of
mitoxantrone . -
pubmed
Overall , the complete response rate was 27.3 % ( 15 of 55
patients , including 4 of 17 with
acute myelogenous leukemia [
AML ] , 4 of 12 with
acute lymphocytic leukemia [
ALL ] , and 7 of 26 with the blastic phase of
CML ) . -
pubmed
METHODS : This was a prospective cohort study of eligible
patients with
pulmonary embolism managed as
outpatients using
dalteparin ( 200 U / kg s / c daily ) for a minimum of five days and
warfarin for 3 months . -
pubmed
Patients were followed for three months for clinically apparent recurrent
venous thromboembolism and
bleeding . -
pubmed
CONCLUSIONS : This prospective study suggests that outpatient management of
pulmonary embolism is feasible and safe for the majority of
patients . -
pubmed
UNLABELLED : The authors evaluate gastric emptying in
diabetic patients and follow up selected factors which may influence it . -
pubmed
The differences of prevalence of
infection according to age groups for
A. - pubmed
The prevalence of
hookworm infection increased steadily with age to reach its maximum ( 37.7 % ) in adulthood ( & gt ; 18 years ) , while
A. - pubmed
In wet highland the prevalence of
infection of
A. - pubmed
Scant information is available about the outcomes of
patients with synchronous
bilateral lung cancers (
SBLC ) treated with radiation . -
pubmed
We report on 32
patients with
SBLC who were treated for palliation by external beam irradiation during a 19 - year period . -
pubmed
Between April 1994 and March 1997 , 143
children ( age range , 1 - 15 years ) with newly diagnosed
acute lymphoblastic leukemia (
ALL ) , except for those
patients with t(9;22 ) , were treated according to protocol-94 of the Osaka Childhood
Leukemia Study Group . -
pubmed
Nineteen
patients with
T - cell ALL were treated with the protocol for the UHRG . -
pubmed
BACKGROUND : Mother - to - child transmission ( MTCT ) of
HIV infection is one of the most tragic consequences of the
HIV epidemic , especially in resource - limited countries , resulting in about 650 000 new paediatric
HIV infections each year world - wide . -
pubmed
This is one of several reviews assessing the available evidence for preventing
HIV transmission from an
HIV - infected woman to her child . -
pubmed
No clear differences could be established when comparing samples from
patients with different
tumor Gleason grades . -
pubmed
METHODS : Fifty - six ankles ( fifty - two
patients ) with a
tibial plafond fracture were treated with a uniform technique consisting of application of a monolateral hinged transarticular external fixator coupled with screw fixation of the articular surface . -
pubmed
Thirty - one
patients with thirty - five involved ankles returned between five and twelve years after the
injury for a physical examination , assessment of
ankle pain and function with the Iowa Ankle Score and
Ankle Osteoarthritis Scale , assessment of general health status with the Short Form-36 ( SF-36 ) , and radiographic examination of the ankle . -
pubmed
Random Amplification of Polymorphic DNA ( RAPD ) assay was used to study DNA typing of 24
strains of
S. - pubmed
OBJECTIVE : Thirty - eight
patients of
laryngeal cancer were treated by extended frontal - lateral laryngectomy and the results were evaluated . -
pubmed
METHODS : Thirty - eight
patients with
laryngeal cancer were treated by frontal - lateral laryngectomy and the
laryngeal defects were reconstructed by epiglottic flap , bi - pedicle and bi - muscle flap and epiglottic flap plus bi - pedicle and bi - muscle flap from February 1988 to February 2000 . -
pubmed
Frontostriatal abnormalities in
adolescents with
bipolar disorder : preliminary observations from functional MRI . -
pubmed
OBJECTIVE : This study investigated whether the functional abnormalities in prefrontal systems observed in adult
bipolar disorder are manifested in
adolescents with this illness . -
pubmed
METHOD : Ten
adolescents with
bipolar disorder and 10 healthy comparison
subjects participated in a color - naming Stroop task during event - related functional magnetic resonance imaging . -
pubmed
In the
bipolar disorder subjects ,
depressive symptoms correlated positively with signal increases in the ventral striatum . -
pubmed
CONCLUSIONS : These findings suggest the presence of dysfunction in the subcortical portions of the frontostriatal circuits in
adolescents with
bipolar disorder . -
pubmed
In an ongoing
CADASIL study , we noted a number of
patients with early acute
myocardial infarction ( before the age of 50 years ) , as well as patients with electrocardiogram ( ECG ) abnormalities . -
pubmed
Method for adapting the virus of
rinderpest to
rabbits . -
pubmed
ANTIBODIES PRODUCED BY
GUINEA PIGS INFECTED WITH
FOOT - AND - MOUTH DISEASE VIRUS . -
pubmed
We are investigating the morphogenesis of
foot - and - mouth disease virus and
African swine fever virus by the use of high - pressure freezing of infected cells . -
pubmed
Therefore regarding daily clinical practice , HRT certainly remains useful to control the symptoms of
oestrogen deficiency in recently menopausal
patients , but it should definitively no longer be recommended for long - term treatment . -
pubmed
[
Acute thrombocytopenic purpura with
meningeal hemorrhage , during
chicken pox , cured by splenectomy ] . -
pubmed
METHODS : We studied 31
patients with endoscopy - negative
GERD , 15
patients with erosive
RE , and 15 asymptomatic controls . -
pubmed
The role of craniospinal irradiation in
adults with a central nervous system
recurrence of
leukemia . -
pubmed
BACKGROUND : Although central nervous system ( CNS ) prophylaxis in
patients with
leukemia has reduced the incidence of
CNS disease recurrence , it still is reported to occur in approximately 5 - 10 % of cases , resulting in a median survival of 6 months . -
pubmed
Craniospinal irradiation ( CSI ) has been shown to improve survival in
children who develop a CNS
recurrence of
acute lymphocytic leukemia (
ALL ) . -
pubmed
However , to the authors ' knowledge , the role of CSI in
adults with a CNS
recurrence of
leukemia is unknown . -
pubmed
METHODS : A retrospective review of adult
patients treated with CSI for a CNS
recurrence of
leukemia identified 16
patients treated between 1986 and 2001 . -
pubmed
The diagnoses included seven
patients with
acute myelogenous leukemia (
AML ) , eight
patients with
ALL , and one
patient with
chronic myelogenous leukemia in
blast crisis . -
pubmed
All
patients had achieved a complete disease remission prior to the CNS
recurrence . -
pubmed
Eleven
patients had an isolated CNS
recurrence and 5
patients had concurrent disease identified in the blood / bone marrow . -
pubmed
RESULTS : One
patient failed to complete radiation treatment because of
disease progression . -
pubmed
No CNS
recurrences occurred , but there were 11
bone marrow failures , 2
patients without
recurrence at & gt ; 5 years , and 3
deaths without a documented site of failure . -
pubmed
However , the eradication of disease in the CNS was not found to be effective at preventing disease
recurrence in the bone marrow , and despite improved control of disease in the CNS , adult
patients with a CNS recurrence still had a poor prognosis . -
pubmed
Dried blood -
spot test monitors
HIV treatment . -
pubmed
Prospective protective role of
melatonin against
arsenic - induced
metabolic toxicity in
Wistar rats . -
pubmed
Arsenic treatment ( as
sodium arsenite ) of male
Wistar rats ( weighing 130 - 150 g ) at a dose of 5.55 mg kg(-1 )
body weight ( equivalent to 35 % of LD(50 ) ) ( i.p . ) -
pubmed
Factors such as less advanced age , the presence of fewer comorbid conditions , or a less florid inflammatory response among
HIV - infected individuals may account for differences in outcome of invasive
PD . -
pubmed
PURPOSE : We investigated
patient outcome and factors affecting obliteration rate after radiosurgery in
cerebral arteriovenous malformations (
AVM ) . -
pubmed
MATERIAL AND METHODS : We have treated 110
patients with
cerebral AVM with linac - based radiosurgery ( RS ) . -
pubmed
Fifty - two
patients experienced
hemorrhage prior to RS . -
pubmed
Neurological dysfunction improved / completely dissolved or remained stable in 95 % of
patients . -
pubmed
RESULTS : Of the 70
patients , 36 had
colorectal liver metastasis , 24 had
cholangiocarcinoma , 4 had
hepatocellular carcinoma , and the remaining 6 had other
tumors . -
pubmed
Postoperative morbidity ( 87 % versus 35 % , P & lt ; 0.001 ) and mortality ( 20 % versus 5 % , P = 0.108 ) were observed more frequently in
patients with preoperative
obstructive jaundice than in those without
jaundice . -
pubmed
Survival for
patients with
colorectal liver metastasis undergoing left hepatic trisectionectomy with concomitant partial resection of the remnant liver was similar to those without this concomitant procedure . -
pubmed
Concomitant partial resection of the remaining liver appears to be safe and offers the potential for cure in
patients with colorectal
metastasis affecting all liver segments . -
pubmed
Tolerability to 1 - year treatment with once - daily
molsidomine in
patients with
stable angina . -
pubmed
Prolonged - release
molsidomine 16 mg once daily ) QD ( has proved effective in the short - term treatment of
patients with
stable angina . -
pubmed
A total of 320
patients with
stable angina were treated for 1 year with
molsidomine 16 mg QD administered open label as monotherapy or add - on therapy , when beta blockers and/or
calcium antagonists were prescribed concomitantly ) in 128
patients , ie , 40 % of cases ) , depending on the severity of disease and/or local therapeutic policies . -
pubmed
Headache accounted for 80.6 % of all drug - related AEs and required discontinuation of the drug in one quarter of
patients who reported the symptom ( ie , 1.9 % of the 320
patients involved in the study ) . -
pubmed
Molsidomine 16 mg QD administered for 1 y to
patients with
stable angina was well tolerated and remained effective during the entire treatment period , independent of age and concomitant antianginal therapy . -
pubmed
Beneficial effects of LK-4 , an analog of
dextromethorphan on lipopolysaccharide - induced
sepsis in
rats . -
pubmed
,
hypotension and
tachycardia ) in
rats treated with LPS . -
pubmed
Contributions of
histamine ,
prostanoids , and
neurokinins to
edema elicited by
edema toxin from
Bacillus anthracis . -
pubmed
We evaluated the direct effect of ET on several cell types in vitro and tested the possibility that mediators of vascular leakage , such as
histamine , contribute to
edema in
rabbits given intradermal ET . -
pubmed
Re : The age - related decrease in
testosterone is significantly exacerbated in
obese men with the
metabolic syndrome . -
pubmed
After discussing alternative model systems like transgenic
mouse models and
canine xenografts , we argue that companion
animals with spontaneous
brain cancers offer a scientifically and ethically attractive system for preclinical testing of novel MG interventions . -
pubmed
Ethical advantages and practical challenges of companion
animal brain cancer trials are briefly discussed . -
pubmed
In January 2005 , we implemented a treatment protocol that included intrapleural
streptokinase ( STK ) for
children with complicated
parapneumonic empyema as an alternative to surgery . -
pubmed
OBJECTIVES : To describe the results of intrapleural STK in the treatment of hospitalized
children with complicated
parapneumonic empyema and to compare these results with those of early thoracotomy . -
pubmed
PATIENTS AND METHODS :
Children with complicated parapneumonic
empyema admitted between January 1st 2004 and October 1st 2005 were included . -
pubmed
CONCLUSIONS : Intrapleural
STK is a valid alternative for the treatment of
children with complicated
parapneumonic empyema . -
pubmed
Nov. , from
hamster dental plaque . -
pubmed
, was isolated from
dental plaque of
golden hamsters fed with a high -
carbohydrate diet . -
pubmed
We present a case of
retrobulbar hemorrhage complicating sub - Tenon 's anesthesia in a
patient receiving oral anticoagulants . -
pubmed
Although
rhinsporidiosis caused by
Rhinosporidium seeberi is known to mankind since hundred years , many aspects of this enigmatic disease have remained mysterious till date . -
pubmed
Present status of surgical intervention for
children with intractable
seizures . -
pubmed
We also discuss updates on identification and selection of
children with severe
refractory epilepsy . -
pubmed
[ Influence of age ,
body weight and dose on
sodium valproate plasma concentrations in
children with
epilepsy ] . -
pubmed
METHODS : One hundred and thirty - two
children with
epilepsy ( age : 4 months-6 years , weight : 5 - 25 kg ) were enrolled . -
pubmed
BACKGROUND :
Hot flashes are a major cause of morbidity among postmenopausal
women , including many survivors of
breast cancer . -
pubmed
The objective of this pilot trial was to assess the potential efficacy and safety of
aprepitant for the treatment of
hot flashes in this
patient population . -
pubmed
PATIENTS AND METHODS : Twenty - five postmenopausal
women , aged & gt;/= 45 years , who were experiencing bothersome
hot flashes ( & gt;/= 14 times per week ) for & gt;/= 1 month , were included . -
pubmed
A
tobacco hypersensitivity experiment showed that YM3 could eliminate
carbofuran in soils effectively and safely . -
pubmed
The role of
deer mice and other species of Peromyscus as enzootic reservoirs for
plague remains controversial . -
pubmed
compared with that for the established
plague vector
Oropsylla montana Baker ( 10.63 % ; 95 % CI : 4.18 - 25.91 ) . -
pubmed
At an early time of
infection , colocalization of
KSHV capsid with envelope was observed by immunofluorescence analysis , thus demonstrating endocytosis of intact enveloped virus particles . -
pubmed
INTRODUCTION : Our aim was to evaluate the frequency and risk factors of
posttransplant diabetes mellitus (
PTDM ) at our kidney transplant center , and to compare graft and
patient outcomes between the kidney recipients with and without
PTDM . -
pubmed
All data including recipient and donor demographics , cause of
end - stage renal disease , cytomegalovirus and
hepatitis C virus antibody tests , and
patient and graft outcomes were assessed in relation to
PTDM . -
pubmed
Moreover ,
impaired glucose tolerance was seen in 17 ( 8.4 % ) , 16 ( 7.9 % ) , 17 ( 8.4 % ) , and 19 ( 9.4 % )
patients at the corresponding times , respectively . -
pubmed
Accordingly , 39
patients ( 19.2 % ) were diagnosed to have
PTDM . -
pubmed
The 5 - year
patient and graft survival rates were not significantly different between the kidney recipients with and without
PTDM . -
pubmed
CONCLUSIONS : This study showed that
PTDM is a common
metabolic disorder in our kidney transplant
patients . -
pubmed
Implications of antioxidant enzymes in
human gastric neoplasms . -
pubmed
Gastric
human neoplasms showed significant changes in antioxidant enzymes , that represent the first line in antioxidant protection against radical attack . -
pubmed
Our results are important in enhancing the understanding of the role that these enzymes play in the promotion / suppression of the
carcinogenesis cascade in
human gastric mucosa . -
pubmed
A repeat analysis was done with adjustments for age , sex , race , underlying
cancer , catheter removal , APACHE III score ,
acute renal failure ,
neutropenia , and non -
Candida albicans species . -
pubmed
PATIENT : A 64 - year - old
gentleman was treated for
carcinoma rectum in our institution with neoadjuvant chemoradiation followed by low anterior resection and adjuvant chemotherapy . -
pubmed
CONCLUSIONS : Our data suggest that either bronchial
NO production in
patients who underwent laryngectomy is very low , possibly due to alterations of the mucosa or oxidant production /
inflammation , or that substantial contributions to FENO arise from the larynx , pharynx and mouth , raising FENO despite velum closure . -
pubmed
The urinary
sulfur partition in normal and
cystinuric dogs fed labeled
methionine . -
pubmed
The most frequent antigens that cause
HP worldwide are bird proteins ( pigeon breeders ' disease ) and bacteria (
Saccharopolyspora rectivirgula ) . -
pubmed
OBJECTIVE : To discuss the practical aspects of safe physical activity and sports participation in
children and adolescents with
type 1 diabetes mellitus . -
pubmed
Nonetheless , physical activity and participation in many individual and team sports is possible and highly recommended in the treatment of
type 1 diabetes in
children and adolescents . -
pubmed
CASES : The use of this combined technique is described in 4 cases , including 2
patients with
spinal cord injury and category IV
pressure ulcers and 2
patients with extensive
postsurgical wounds . -
pubmed
RESULTS : Fifty - seven
patients had hepatic complications , including radiological features of
liver cirrhosis ( 25.9 % ) ,
thrombocytopenia ( 7.2 % ) ,
hyperbilirubinaemia ( 20.9 % ) and
hepatic masses ( 2.9 % ) . -
pubmed
CONCLUSION : Late
hepatic dysfunction and cirrhotic change were often seen in Fontan
patients . -
pubmed
METHODS : We examined 39
patients with
DTC who had a clinical history of at least 2 years and compared them with 25
patients who had a pathological diagnosis of
NG after thyroidectomy . -
pubmed
Kirkaldy native populations there , and to avoid the
confusion of the damage that may be caused on
O. - pubmed
geniculata will provide another source for
wheat stem rust resistance breeding and for physical mapping of the resistance locus and crossover hot
spots between
wheat chromosome 5D and chromosome 5M(g)L of
Ae . - pubmed
METHODS : A total of 64
keratocystic odontogenic tumours , arising in forty - six
patients , were evaluated using the following parameters : association with
nevoid basal cell carcinoma syndrome , gender , age at first diagnosis , race , anatomical location , symptoms , radiographic features , history of
recurrence , association with teeth , and treatment . -
pubmed
RESULTS :
Keratocystic odontogenic tumours were more frequent among
women than men ( 1:0.84 ) . -
pubmed
Liver tumor models in transgenic
zebrafish : an alternative in vivo approach to study hepatocarcinogenes . -
pubmed
In the early experiments of carcinogen treatment , it has been found that the induced
tumors in the
zebrafish share many similar features with those of
humans . -
pubmed
With the recent development in transgenic technology , we are able to control the expression of a specific oncogene in targeted organs for generation of different tissue
tumor models in
zebrafish . -
pubmed
In particular , the fusion of an oncogene and a color reporter , such as the green fluorescent protein , allows us to conveniently monitor transgenic
tumors for their initiation , progression ,
metastasis and transplantation in the transparent
zebrafish embryos , as demonstrated in this article with our newly established
liver cancer models . -
pubmed
A 42 - year - old female
patient underwent mastectomy with axillary lymph node dissection for
breast cancer in 2001 . -
pubmed
Chronic
arsenic exposure remains a
human health risk ; however a clear mode of action to understand gene signaling - driven
arsenic carcinogenesis is currently lacking . -
pubmed
This study chronically exposed
human lung epithelial
BEAS-2B cells to low - dose
arsenic trioxide to elucidate
cancer promoting gene signaling networks associated with
arsenic - transformed ( B - As ) cells . -
pubmed
B - As injections into
nude mice resulted in development of primary and secondary
metastatic tumors . -
pubmed
In summary , our excision - free optical biopsy technique is ideal for longitudinal microscopic analysis of
animal skin and skin innervations in vivo and can be applied widely in preclinical models of
chronic pain ,
allergies ,
skin cancers and a variety of
dermatological disorders . -
pubmed
In the present study , we investigated the effects of the
Autographa californica nucleopolyhedrovirus (
AcMNPV )
infection on autophagy in
SL - HP cell line from
Spodoptera litura induced under
amino acid deprivation . -
pubmed
The results revealed that
AcMNPV infection did not inhibit autophagy but triggered apoptosis under
starvation pressure . -
pubmed
METHODS : Genome - wide DNA methylation changes between relapse and remission in monocytes ( n = 6 ) and naive T helper cells ( Th0s ) ( n = 4 ) isolated from
patients with
MCNS were investigated using the microarray - based integrated analysis of methylation by isochizomers ( MIAMI ) method . -
pubmed
Serratia marcescens associated
ampullary system infection and
septicaemia in a
bonnethead shark ,
Sphyrna tiburo ( L. ) . -
pubmed
Seventy - eight
patients underwent deep
hypothermia ( mean lowest temperature , 16.8 C + - 1.7 C ) and 143
patients underwent moderate
hypothermia ( mean , 22.9 C + - 1.4 C ) before systemic circulatory arrest was initiated . -
pubmed
OBJECTIVE : We aimed to assess sensitivity and specificity of the updated criteria for behavioral variant
frontotemporal dementia (
bvFTD ) based on a large autopsy - confirmed cohort of
patients with
dementia . -
pubmed
METHODS : Two hundred thirty - nine consecutive pathologically confirmed
dementia patients , clinically assessed in a specialist cognitive unit were identified . -
pubmed
Patients with predominant
aphasia ,
motor disorders , or insufficient clinical information were excluded . -
pubmed
RESULTS : The final study cohort comprised 156
patients with predominantly early - onset
dementia . -
pubmed
Patients with
chronic renal failure in use of peritoneal dialysis ( PD ) are subject to various complications of the renal replacement therapy . -
pubmed
This report describes the case of a
patient who had a second
squamous cell carcinoma (
SCC ) in the center of the skin island of a forearm flap raised approximately 6 years previously . -
pubmed
METHODS : Affective ToM was assessed with the Reading the Mind in the Eyes task in 35
PD patients and 35 healthy controls . -
pubmed
Patients were distinguished in early
PD and moderate
PD according to their scores in the Hoehn and Yahr Staging Scale . -
pubmed
Influence of
Salmonella enterica serovar Enteritidis infection on the composition of
chicken cecal microbiota . -
pubmed
BACKGROUND :
Infection of newly hatched chicks with
Salmonella enterica serovar Enteritidis (
S. - pubmed
Enteritidis infection influences the composition of the cecal microbiota in
chickens but these changes are minor in nature and should be understood more as an indirect consequence of
infection and
inflammation rather than a positively selected evolutionary trait . -
pubmed
[ IAG regimen for
patients with refractory / relapsed
acute myeloid leukemia ] . -
pubmed
43
children , 3 - 18 year old ( 23 females , median age 10 years ) , presenting with recurrent
headache from April , 2011 to January , 2012 , were enrolled . -
pubmed
26
patients ( 60.5 % ) had
headache with
migraine features ( 11 had
Tension type headache and 4 had non - specific
headaches ) . -
pubmed
Fresh frozen plasma ( FFP ) has been used in
human OP pesticide
poisoning which prompted us to investigate the in vitro kinetics of OP nerve agent degradation by FFP . -
pubmed
FFP does not seem to be suitable for detoxifying relevant agent concentrations in case of
human poisoning by V - type nerve agents . -
pubmed
Clinical symptoms of
respiratory distress resolved in the early postoperative period , and the
patient became hemodynamically stable . -
pubmed
[ Effects of non - surgical periodontal treatment on clinical response , serum inflammatory parameters , and metabolic control of
type 2 diabetes patients with moderate to severe
periodontitis ] . -
pubmed
OBJECTIVE : To evaluate the effects of periodontal treatment on the clinical response , systemic inflammatory parameters , and metabolic control of
type 2 diabetes patients with moderate to severe
periodontitis . -
pubmed
CONCLUSION : Non - surgical periodontal treatment can effectively improve periodontal status , circulating inflammatory status , and metabolic control of
diabetic patients with moderate to severe
periodontitis . -
pubmed
The first case of
bacteraemia due to non - O1 / non - O139
Vibrio cholerae in a
type 2 diabetes mellitus patient in mainland China . -
pubmed
Bacteraemia due to non - O1 / non - O139
Vibrio cholerae is rarely documented in mainland China . -
pubmed
The feedback negativity ( FN ) , an ERP index of reward evaluation , was recorded in 34 unmedicated
depressed individuals and 42 never -
depressed controls during a laboratory gambling task . -
pubmed
Ventral striatal ( VS ) activation to reward was recorded in a separate fMRI session , using an identical task , among a subgroup of 24
depressed individuals and a comparison group of 18 non - depressed controls . -
pubmed
In
patients with significant
emesis co - occurring during an attack , additional antiemetics such as
metoclopramide or
domperidone may be administered . -
pubmed
The treatment success of the individual
patient is difficult to predict both in acute and prophylactic
migraine treatment . -
pubmed
The committee recommended , though not unanimously , that ( 1 ) the current data does not support the conclusion that
naproxen has a lower risk of
thrombotic events than other NSAIDs ; ( 2 ) there is no latency period for the risk of cardiovascular
thrombotic events ; ( 3 ) there are some
patient populations at increased risk for events ; and ( 4 ) equipoise remains in the major ongoing trial designed to address these issues further . -
pubmed
The objective of this study was to evaluate if peritumoral ( PT ) perfusion parameters obtained from dynamic susceptibility weighted contrast enhanced perfusion MRI can predict overall survival ( OS ) and progression free survival ( PFS ) in
patients with newly diagnosed
glioblastoma multiforme (
GBM ) . -
pubmed
Twenty - eight newly diagnosed
GBM patients , who were treated with resection followed by concurrent chemoradiation and adjuvant chemotherapy , were included in this study . -
pubmed
Our study found posttreatment , not pretreatment , PT perfusion parameters can be used to predict OS and PFS in
patients with newly diagnosed
GBM . -
pubmed
Intravesical instillation of
amikacin for treatment of a lower
urinary tract infection caused by
Pseudomonas aeruginosa in a
dog . -
pubmed
CASE DESCRIPTION : A 9 - year - old neutered male
Golden Retriever was evaluated because of recurrent lower
urinary tract infection subsequent to placement of a permanent cystostomy tube . -
pubmed
CLINICAL RELEVANCE : In this
dog , treatment of a lower
urinary tract infection caused by a multidrug - resistant strain of
P aeruginosa was successfully achieved with intravesical instillation of
amikacin . -
pubmed
Intravesical instillation of antimicrobials may be a viable treatment option for
dogs with lower
urinary tract infections caused by multidrug - resistant bacteria . -
pubmed
CONCLUSION : Limited published data exists reporting the effectiveness of measures in the treatment of
xerostomia in
cancer patients . -
pubmed
DESIGN : In
humans , we mined genome - wide meta - analysis data sets to examine purinergic signaling genes for association with glycemic traits and
type 2 diabetes . -
pubmed
Generation of
human acute lymphoblastic leukemia xenografts for use in oncology drug discovery . -
pubmed
The establishment of reproducible
mouse models of
acute lymphoblastic leukemia (
ALL ) is necessary to provide in vivo therapeutic test systems that recapitulate
human ALL , and for amplification of limited amounts of primary
tumor material . -
pubmed
The protocol includes injection of primary
patient tumor specimens into
mice with subsequent serial passaging of the
tumors by retransplants of cells harvested from the
mouse bone marrow and spleen . -
pubmed
PATIENTS AND METHODS : Seventy - five
patients with
extremity trauma suspicious for
arterial injury were examined by color Doppler USG just before angiography . -
pubmed
CONCLUSIONS : Color Doppler USG can be used as a reliable modality with acceptable sensitivity and specificity values to screen hemodynamically stable
patients with
limb trauma suspicious for
arterial injury . -
pubmed
The use of dynamic susceptibility contrast ( DSC ) MRI to automatically classify
patients with first episode
psychosis . -
pubmed
The aim of this work is to automatically discriminate first episode
psychosis patients and normal controls on the basis of brain perfusion employing a support vector machine ( SVM ) classifier . -
pubmed
In conclusion , we found evidence that brain perfusion could be used as a potential marker to classify
patients with
psychosis , who show reduced blood flow and volume in respect to normal controls . -
pubmed
Rosuvastatin Decreases Mean Platelet Volume in
Patients With
Diabetes Mellitus . -
pubmed
We evaluated the effects of
rosuvastatin on mean platelet volume ( MPV)--a marker for platelet activity -- in
patients with
diabetes mellitus (
DM ) on
rosuvastatin medication . -
pubmed
The antiplatelet activation properties of high - dose
rosuvastatin treatment in
patients with
DM are not lipid dependent . -
pubmed
Accumulated evidence from experimental
animal models suggests that neuroplastic changes at the dorsal horn are critical for the maintenance of various chronic
musculoskeletal pain conditions . -
pubmed
These data reveal that chronic
musculoskeletal pain in
humans is associated with discrete alterations in the anatomy of the medullary dorsal horn , as well as its afferent and efferent projections . -
pubmed
Notably , plasma
thiocyanate levels are increased in smokers , and leukocyte - driven protein carbamylation occurs both within
human and animal
atherosclerotic plaques , as well as on plasma proteins . -
pubmed
Characterization of microRNA expression profiling in peripheral blood lymphocytes in
rats with experimental
autoimmune uveitis . -
pubmed
OBJECTIVE AND DESIGN : We aimed to investigate the alterations of microRNA ( miRNA ) genomics in peripheral blood lymphocytes in experimental
autoimmune uveitis (
EAU )
rats versus control samples . -
pubmed
RESULTS : The results indicated that 36 miRNAs were upregulated and 31 miRNAs were downregulated in
EAU rats versus normal samples . -
pubmed
CONCLUSIONS : Our findings show that the differentially expressed miRNAs in
EAU rats were closely associated with immune signaling pathways and may be applied in early prevention , prognosis and possible therapy in
uveitis , indicating that miRNAs play an important role in the development of
uveitis . -
pubmed
The effects of intravenous
fosaprepitant and
ondansetron in the prevention of
postoperative nausea and vomiting in
patients who underwent lower limb surgery : a prospective , randomized , double - blind study . -
pubmed
All
patients received postoperative epidural
fentanyl for
pain control . -
pubmed
METHODS : Between 2006 and 2014 , six
patients affected by
infection and
necrosis after Achilles tendon open repair underwent multi - tissutal reconstruction by a composite radial forearm free flap including a vascularized FCR tendon . -
pubmed
METHODS : In total , 47
overweight and obese
men who had been referred for suspected
OSA underwent polysomnography and were classified based on the
apnea - hypopnea index ( AHI ) into three groups : no
OSA , & lt ; 5 events / h ( n = 11 ) ; mild
OSA , & gt;= 5 to & lt ; 15 events / h ( n = 8) ; and moderate - severe
OSA , & gt;= 15 events / h ( n = 28 ) . -
pubmed
The proportions of
patients with
MS were different between the three groups ( 18.2 % in no
OSA ; 25 % in mild
OSA , and 57.1 % in moderate - severe
OSA ; p = 0.047 ) . -
pubmed
Validation of Serological Antibody Profiles Against
Human Papillomavirus Type 16 Antigens as Markers for Early Detection of
Cervical Cancer . -
pubmed
During the virus life cycle and in the process toward
malignancy , different
human papillomavirus (
HPV ) proteins are expressed , and they induce a host humoral immune response that can be used as a potential marker for different stages of the disease . -
pubmed
Since the 1950s , there have been reports of
loblolly pines showing reduced growth and increased mortality , particularly in central Alabama and western Georgia , United States ; the phenomenon is termed as southern pine decline (
SPD ) . -
pubmed
Recently , the role of rhizophagous ( root - feeding ) insects in
loblolly pine health within the context of
SPD has come under greater scrutiny . -
pubmed
Cerebral
Glucose Metabolism and Dopaminergic Function in
Patients with
Corticobasal Syndrome . -
pubmed
Safety and efficacy of
vismodegib in
patients with
basal cell carcinoma nevus syndrome : pooled analysis of two trials . -
pubmed
It is unclear whether
BCCs arising in
patients with
BCCNS respond differently to
vismodegib than in
patients without
BCCNS . -
pubmed
We examined the best overall response rate ( BORR ) and adverse events ( AEs ) of
vismodegib in
patients with advanced
BCC (
aBCC ) with and without
BCCNS . -
pubmed
RESULTS : Forty - one
patients with
BCCNS were included in the study : 22 from ERIVANCE BCC and 19 from the EAS . -
pubmed
Investigator - assessed BORR in BCCNS groups ranged from 31 to 81 % in
patients with locally advanced
BCC ( n = 33 ) and was 50 % in
patients with metastatic
BCC ( n = 6 ) . -
pubmed
Amenorrhea was observed in both
patient cohorts and was reversible in two
patients who discontinued treatment . -
pubmed
High expression of miR-33a suppressed xenograft
tumor growth and dissemination in
nude mice . -
pubmed
The downregulation of miR-33a was closely associated with advanced clinical stage , lymph node
metastasis , and poor clinical outcomes in
patients with
GBC . -
pubmed
BACKGROUND :
Cellulite is a common aesthetic condition that affects almost every
woman . -
pubmed
METHODS : In this open - label , single - centre trial , 30
women presenting moderate or severe
cellulite underwent 12 sessions of AWT on the gluteus and back of the thighs , over six weeks . -
pubmed
In 28
patients ( 87.5 % ) , there was peritoneal fluid , which was blood in 14
patients (
hematoma in 11
patients and contrast material extravasation from active
bleeding in 3
patients ) . -
pubmed
CONCLUSION : A radiologic score is helpful for guiding the diagnosis and management ( surgical or conservative ) of
gastric blunt traumatic injuries and stratify
patients according to short - term outcomes . -
pubmed
This systematic review discusses in vivo
animal and
human studies of the physiological and biochemical effects of
chlorogenic acids (
CGAs ) on biomarkers of
chronic disease . -
pubmed
METHODS AND MATERIALS : For a cohort of 100
patients with
STS of the extremity / trunk treated at our institution with preoperative RT followed by resection , 2 expert
sarcoma pathologists evaluated the resected specimens for percent residual viable cells ,
necrosis ,
hyalinization /
fibrosis , and
infarction . -
pubmed
The device - oriented composite end point of
cardiac death , target - vessel
myocardial infarction and target - lesion revascularization occurred in 13 ( 16 % )
patients treated with EES , in 7 ( 9 % )
patients treated with BES and in 16 ( 21 % )
patients treated with BVS . -
pubmed
There was one late scaffold
thrombosis throughout the trial in the BVS group , and no definite stent
thrombosis in either EES or
BES treated
patients . -
pubmed
Nephrogenic systemic fibrosis (
NSF ) , previously known as
nephrogenic fibrosing dermopathy , is a rare complication of exposure to
gadolinium - based contrast agents in
patients who have significantly
decreased renal function . -
pubmed
Photopheresis has been tried with variable rates of improvement , and small numbers of cases ( 20 as of 2016 ) have been reported of
NSF patients treated with photopheresis . -
pubmed
We report a case of
patient with
nephrogenic systemic fibrosis who was treated with photopheresis and demonstrated significant lasting improvements . -
pubmed
BACKGROUND : Enterovirus (
EV ) and
herpes simplex virus 1 and 2 (
HSV1 and
HSV2 ) are the main etiologic agents of
central nervous system infections . -
pubmed
RESULTS : We tested 87 CSF samples of
patients with a clinical diagnosis of
viral meningitis or
encephalitis . -
pubmed
Patients were excluded for & lt;2 years in the plan before the index date , any history of
nAMD or diagnosis , or treatment for an
ocular disease that could be confused with
nAMD . -
pubmed
Primary analysis compared BB with CCB
patients with
BB versus the other classes as secondary analyses . -
pubmed
After controlling for covariates ,
patients on BB had a lower hazard for
nAMD at both 90 and 180 days than
patients on
CCB ( HRs : 0.67 - 0.71 ; P & lt ; 0.01 for both ) and diuretics ( HRs : 0.55 - 0.62 ; P & lt ; 0.01 ) . -
pubmed
A sensitivity analysis using propensity score matching yielded similar results with
patients on BB significantly less likely to develop
nAMD at 90 and 180 days ( HR : 0.70 - 0.76 ; P & lt ; 0.049 for both ) but not at 365 days ( HR : 0.88 ; P = 0.30 ) compared with patients on
CCB . -
pubmed
However , a few
patients may develop different types of
pain after
herpetic lesions . -
pubmed
We are reporting two
patients who developed
postherpetic hemicrania continua (
HC ) . -
pubmed
Case 1 : a 54 - year - old
woman had a 10 - month history of continuous left - sided
pain with superimposed exacerbations . -
pubmed
Case 2 : a 61 - year - old
woman developed clinical features pertinent to
PHN . -
pubmed
We suggest that every
patient with
PHN should be asked for cranial autonomic features and a trial of
indomethacin should be given in refractory
herpes zoster neuropathy . -
pubmed
For Japanese
encephalitis positive
patients , mean age was 36 ( range 4 - 80 ) . -
pubmed
This study identified structural and functional brain connectivity alterations in two independent samples of
patients along the
posterior cortical atrophy ( PCA ) disease course . -
pubmed
Twenty - one
PCA patients and 44 controls were recruited from two expert centres . -
pubmed
PCA
patients showed distributed
WM damage . -
pubmed
METHODS : A large collection of RMR measurements and energy intake was assembled in mechanically ventilated and
critically ill patients . -
pubmed
Recent epidemiological studies suggest that
human exposure to
perfluoroalkyl substances ( PFASs ) may be associated with
type 2 diabetes and other metabolic phenotypes . -
pubmed
Prevalence of
bone pain decreases as lymph node stage increases in
nonsmall cell lung cancer patients . -
pubmed
We investigated the appropriate use of bone imaging in
nonsmall cell lung cancer (
NSCLC )
patients . -
pubmed
One hundred seventy - seven consecutive
NSCLC patients who had distant metastases at presentation and were admitted between January 2012 and April 2016 were retrospectively reviewed . -
pubmed
Among
patients with
bone metastases , we explored
bone pain , number of
bone metastases , location of
bone metastases , and clinical
tumor ( T ) and lymph node ( N ) classification . -
pubmed
Sixty - three
patients had bone
metastases . -
pubmed
N0 and N2 - 3
patients were more likely to have multiple
bone metastases ( p = 0.038 ) . -
pubmed
Compared with
patients who had a single
bone metastasis ,
patients with multiple
metastases had a significantly higher probability of having at least 1 bone
metastasis located in the thorax or upper abdomen . -
pubmed
All N0
patients have at least 1 bone
metastasis in the thorax or upper abdomen . -
pubmed
Clinical N0
NSCLC patients with
bone metastasis are likely to have
bone pain and have multiple
bone metastases . -
pubmed
N2 - 3
patients are more likely to have
bone metastases but less likely to have
bone pain . -
pubmed
Objective :
Patients with
type 1 diabetes mellitus (
T1DM ) are
insulin dependent . -
pubmed
Participant : A 29 - year - old Hispanic
woman with known history of long - standing , uncontrolled
T1DM presented for evaluation of worsening
dysphagia and
dyspnea . -
pubmed
This review focuses on recent advances in our understanding of ISC identity , behavior , and regulation during homeostasis and
injury - induced repair , as revealed by two major
animal models used to study regeneration of the small intestine :
Drosophila melanogaster and
Mus musculus . -
pubmed
MATERIALS AND METHODS : We analyzed data from
women treated in one center with adjuvant interstitial HDR brachytherapy for early - stage
breast cancer . -
pubmed
Treatment regimen was homogeneous for all
women with treatment dose 32Gy in 8 fractions twice daily given to the
tumor bed with interstitial HDR brachytherapy . -
pubmed
Three DNA extraction methods were compared for relative yield and sensitivity of detection of
CMV DNA : thermal
shock ,
KOH Tris buffer , and DNA Extract All . -
pubmed
Moderate to severe
pancreatitis developed in 4
patients ( 0.9 % ) in the combination group , and 10
patients ( 2.3 % ) in the
diclofenac - alone group ( relative risk 0.12 ; 95 % confidence interval 0.13 - 1.26 ; P = .12 ) . -
pubmed
To our knowledge , this is the first report of natural
infection of
onion by
B. - pubmed
BACKGROUND : Torquetenovirus (
TTV )
viremia is emerging as a promising tool to assess functional immune competence , to predict posttransplant immune - related complications , and eventually to customize immunosuppression . -
pubmed
CONCLUSIONS : These findings provided us a valuable approach for detection and differentiation the
HEV infection derived from genotypes 1 , 2 (
human ) or genotypes 3 , 4 (
zoonosis ) . -
pubmed
Human Dendritic Cell Subsets , Ontogeny , and Impact on
HIV Infection . -
pubmed
Even though
HCV infection morbidity rate in children is relatively low in comparison with the adult population , approximately 5 million children in the world have active
HCV . -
pubmed
Co - infection of
Pneumocystis jirovecii and Aspergillus in a patient with
idiopathic thrombocytopenic purpura . -
pubmed
INTRODUCTION : Mortality risk and outcome in
critically ill patients can be predicted by scoring systems . -
pubmed
Acute kidney injury (
AKI ) is also one of the strongest factors negatively influencing
patients ' fate . -
pubmed
OBJECTIVES : We aimed to evaluate the value of MR - proADM in incident
AKI and mortality prognostication among
patients admitted to the intensive care unit ( ICU ) in comparison to commonly used scoring systems . -
pubmed
35
patients ( 22 % ) developed
AKI by 3 days post -
ARDS diagnosis , and 25 ( 16 % ) died by 60 days post -
ARDS diagnosis . -
pubmed
METHODS : Ninety healthy controls , 30
patients with
major depressive disorder (
MDD ) , 35
patients with
mild cognitive impairment (
MCI ) , and 55
patients with
ADD performed a Symbol Processing Task with 4 different symbol categories . -
pubmed
RESULTS : Analyses revealed a higher symbol comprehension accuracy in healthy seniors than in
MDD ,
MCI , and
ADD patients , with the lowest accuracy rates shown by
ADD patients . -
pubmed
At last ,
nude mice xenograft was used to further investigate the anti -
tumor effect of SMA /
CORM-2 in vivo . -
pubmed
In vivo , SMA /
CORM-2 treatment remarkably suppressed
tumor growth and lung
metastasis in
nude mice . -
pubmed
PURPOSE : Surgical resection of primary
tumor with regional lymphadenectomy remains the treatment of choice for
patients with advanced
human papillomavirus - negative head and neck squamous cell carcinoma . -
pubmed
OBJECTIVE : To evaluate the presence of tau deposition and pathologic features of
chronic traumatic encephalopathy (
CTE ) in young adult
patients treated with focal cortical resections for
drug - resistant epilepsy . -
pubmed
METHODS : Sixty consecutive
patients who had undergone surgical treatment for drug - resistant
focal epilepsy between 18 and 45 years of age were identified ( 2010 - 2017 ) . -
pubmed
A history of
head trauma was reported in 19
patients . -
pubmed
Three of these 4
patients had no significant history of
head trauma ; 1
patient had multiple sports - related
concussions . -
pubmed
Diagnostic features of
CTE were not detected in any
patient ; however , the pathological evaluation for
CTE was limited to a surgical specimen . -
pubmed
All flaps survived , dental occlusion was achieved in all
patients , no
tumors recurred , masticatory function was normal without swallowing or speech alterations , and the transplanted bone hypertrophied and spontaneously remodeled , providing facial symmetry with good aesthetic results . -
pubmed
Listeria monocytogenes is an important foodborne pathogen , causative agent of
listeriosis . -
pubmed
In addition , none of the
strains which were not ascribed to
L. - pubmed
Methods : Fibroblasts isolated from the hips of
patients with
AS were induced to osteogenesis . -
pubmed
A proteoglycan - induced
arthritis (
PGIA ) Balb / c
mouse model was established in order to monitor sacroiliac joint ( SIJ )
inflammation and subsequent damage through magnetic resonance image . -
pubmed
The
patient has been alive for 15 months without
recurrence . -
pubmed
Long - Term Safety and Durability of Effect With a Combination of
Olanzapine and
Samidorphan in
Patients With
Schizophrenia : Results From a 1 - Year Open - Label Extension Study . -
pubmed
However , as
SARS - CoV-2 mutates , we need to constantly assess whether existing PCR - based assays will continue to detect all known viral
strains . -
pubmed
Sedentary behavior and
cognitive impairment have a direct impact on
patients ' outcomes . -
pubmed
An energy
metabolic disorder may be involved in the overlap of these comorbid conditions ( motoric cognitive risk ( MCR ) ) in
patients with
chronic obstructive pulmonary disease (
COPD ) . -
pubmed
This protein was not disease - specific but could be a screening biomarker to detect MCR related to poor health outcomes of
COPD patients . -
pubmed
Food impaction mimicking dislodgment of a lumen - apposing metal stent in a
patient undergoing endoscopic ultrasound - guided gallbladder drainage for
acute cholecystitis . -
pubmed
PURPOSE : Sedation management of
trauma patients after damage control laparotomy ( DCL ) has not been optimized . -
pubmed
We calculated the propensity for each
patient to achieve DFC using age , gender , ISS , red blood cell transfusion , bowel discontinuity ,
abdominal vascular injury , and time to first takeback ; we then determined the effect of sedation exposure on rate of DFC by multivariate Cox regression , adjusted for propensity to achieve DFC . -
pubmed
For each study , information was recorded regarding
mouse strain and sex ;
corticosterone sample matrix and quantification technique ; and whether the studies covered the research themes
animal welfare , neuroscience , stress ,
inflammation , or
pain ( the themes of specific interest in our consortium ) . -
pubmed
METHODS :
Patients with
mRCC and spinal involvement from June 2005 to November 2018 were identified . -
pubmed
RESULTS : One hundred
patients with 685 spinal levels involved by
mRCC were evaluated . -
pubmed
Patients with smaller
tumors ( < 4 cm ) and local spread had distribution of
spinal metastases not significantly different from uniform ( P = 0.292 and P = 0.126 , respectively ) . -
pubmed
Re : Results of a randomized trial of treatment modalities in
patients with low or early - intermediate risk
prostate cancer ( PREFERE trial ) . -
pubmed
Tomatidine ameliorates
obesity - induced
non - alcoholic fatty liver disease in
mice :
Tomatidine improves
hepatic steatosis in
mice . -
pubmed
In this study , we investigated how
tomatidine ameliorates
NAFLD in
obese mice and evaluated the regulatory mechanism of lipogenesis in hepatocytes . -
pubmed
Male
C57BL / 6 mice were fed a high - fat diet ( HFD ) to induce
obesity and
NAFLD , and treated with
tomatidine via intraperitoneal injection . -
pubmed
Our results demonstrate that
tomatidine significantly decreases
body weight and fat weight compared to HFD - fed
mice . -
pubmed
In addition ,
tomatidine decreased hepatic lipid accumulation and improved hepatocyte
steatosis in HFD - induced
obese mice . -
pubmed
Background : The increased survival of
patients with
multiple myeloma (
MM ) raises the question of kidney transplantation ( KT ) in
patients with
end - stage renal disease (
ESRD ) . -
pubmed
Methods : We included 13
patients with
MM or
smoldering myeloma (
SMM ) and
ESRD transplanted between 2007 and 2015 , including 7
MM with
cast nephropathy , 3 with
MM - associated
amyloid light chain amyloidosis or
light chain deposition disease and 3
SMM and compared them with 65 control - matched kidney - transplanted
patients . -
pubmed
Nine of the
MM patients with
KT were also compared with 63 matched
MM patients on haemodialysis . -
pubmed
Results : Pre - transplantation parameters were comparable , except for the duration of renal replacement therapy ( 57.8 versus 37.0 months ; P = 0.029 ) in
MM versus control
patients , respectively . -
pubmed
The median MM graft and
patient survival were 80.1 and 117.2 months , respectively , and were not significantly different from control
patients , although mortality tended to be higher in the 10 symptomatic
MM patients ( P = 0.059 ) . -
pubmed
MM patients had significantly more viral and
fungal infections and immunosuppressive maintenance therapy modifications while they received lower induction therapy . -
pubmed
Two
MM patients relapsed and two
SMM cases evolved to
MM after KT . -
pubmed
Moreover , survival of
MM with
KT increased relative to control haemodialysed
patients ( P = 0.002 ) . -
pubmed
Conclusions : Selected
MM patients may benefit from KT but need careful surveillance in the case of KT complications and
MM evolution . -
pubmed
The aim of this meta - analysis was to investigate whether the blood concentrations of
patients with
multiple sclerosis (
MS ) are associated with those of the healthy control group in terms of trace elements including
zinc (
Zn ) ,
iron (
Fe ) ,
manganese (
Mn ) ,
magnesium (
Mg ) ,
selenium (
Se ) , and
copper (
Cu ) . -
pubmed
Pooled results using random - effects model indicated that the levels of
Zn ( WMD = - 7.83 mcg / dl , 95 % CI = - 12.78 to - 2.87 , Z = 3.09 , P = 0.002 ) , and
Fe ( WMD = - 13.66 mcg / dl , 95 % CI = - 23.13 to - 4.19 , Z = 2.83 , P = 0.005 ) were significantly lower in
MS patients than in controls . -
pubmed
However , it was found that levels of
Mn ( WMD = 0.03 mcg / dl , 95 % CI = 0.01 to 0.04 , Z = 2.89 , P = 0.004 ) were significantly higher in
MS patients . -
pubmed
This meta - analysis revealed that the circulating levels of
Zn and
Fe were significantly lower in
MS patients and that
Mn level was significantly higher than those in the control group . -
pubmed
However , it was found that there was no significant difference between
MS patients and controls with regard to levels of
Mg ,
Se , and
Cu . -
pubmed
A
patient who died from
oat - cell carcinoma of the lung had had
abdominal pain and
obstipation . -
pubmed
Kinetic measurements of the serum appearance and disappearance of
triglycerides in drug - treated
rats suggest that the
hypotriglyceridemic activity is due to a net inhibition of hepatic
triglyceride synthesis . -
pubmed
Preliminary experiments in
rats on the mechanism of its hypoglycemic activity , observed in some
diabetic hyperlipidemic patients , indicate that
halofenate acts differently than conventional oral hypoglycemic agents . -
pubmed
A case of
Escherichia coli septicemia with associated
metastatic en dophthalmitis and
endocarditis is presented . -
pubmed
Recently , three
patients with
acromegaly have been operated upon for active
otologic disease . -
pubmed
In 136
patients with
cicatrical strictures of the esophagus the author performed total esophagoplasty , using the left colon ( 89 cases ) , the right colon with terminal iliac portion ( 8 cases ) , the small intestine by Roux - Herzen - Judin technic ( 27 cases ) and the small intestine with primary reconstruction of the graft ( 12 cases ) . -
pubmed
Study of reticuloendothelial phagocytic capacity in
patients with
cholestasis . -
pubmed
About half of the
patients with
cholestasis showed impaired Kupffer - cell phagocytosis . -
pubmed
The finding may be relevant to the occurrence of surgical complications in
patients with
obstructive jaundice . -
pubmed
The authors reviewed a series of 38 consecutive
patients with
trigeminal neuralgia treated by percutaneous thermocoagulation in 1984 - 90 . -
pubmed
In
patients in whom there was a
sensory impairment after either thermocoagulation or other form of treatment ( injection of
alcohol or rhizotomy ) repeated thermocoagulation not only did not give good results but could lead to worsening of the
pain . -
pubmed
Protection against
benzo [ a ] pyrene- and
N - nitrosodiethylamine - induced lung and
forestomach tumorigenesis in A / J
mice by water extracts of
green tea and
licorice . -
pubmed
Atherogenic profiles in
insulin - dependent diabetic patients and their treatment . -
pubmed
Longitudinal studies have shown a large excess of cardiovascular mortality in
insulin - dependent diabetic patients (
IDDM ) as compared to non - diabetic controls . -
pubmed
xylosus and one
strain of
S. - pubmed
Relationship between redistribution on exercise
thallium-201 scintigraphy and repetitive
ventricular premature beats in
patients with recent
myocardial infarction . -
pubmed
The relationship between
myocardial ischemia detected by exercise
thallium-201 scintigraphy and repetitive
ventricular premature beats ( VPBs ) during ambulatory monitoring was evaluated in 57
patients with recent
myocardial infarction . -
pubmed
Thirty - five
patients had redistribution , but only three of them had repetitive
VPBs during exercise testing . -
pubmed
Obesity and
insulin resistance in
humans : a dose - response study . -
pubmed
Both in the basal state and following a
hyperglycemic stimulus
obese people display
hyperinsulinemia , which correlates with the degree of
insulin resistance . -
pubmed
Considering that
diabetic hypertensive patients are at high risk for
atherosclerosis it appears also favourable that
betaxolol did not increase
triglyceride levels and even decreased total
cholesterol . -
pubmed
[ Effects of
nimodipine on blood pressure and cardiac function in
hypertensive patients ] . -
pubmed
This double - blind randomized placebo - controlled study was designed to evaluate the acute effects of orally administered slow - release
isosorbide-5 - mononitrate (
SR IS-5 - MN ) in 12
patients with
chronic stable angina . -
pubmed
Propranolol is likely to be widely used to prevent
variceal haemorrhage in
patients with
cirrhosis . -
pubmed
However , as long as the exact role of
thiamine compounds in relation to membrane excitability in the nervous system remains unknown , it is impossible to conclude whether the differences observed in the metabolism of
thiamine compounds are the cause or the consequence of the
photosensitivity in the
baboon Papio papio . -
pubmed
Only four
patients subsequently proved to have unequivocal chronic
pancreatitis . -
pubmed
There was no significant difference in the size or contour of the main pancreatic duct , or in side branch changes between those
patients presenting with
common bile duct stones , incidental biliary pathology and
pain of probable pancreatic origin . -
pubmed
We examined 21
patients with
tumours of the mouth , one with
tumour involvement of the facial skeleton and three with lymph node involvement in the upper neck , by nuclear tomography . -
pubmed
Amongst our
patients , nuclear tomography was also superior for showing lymph node
metastases . -
pubmed
Fluid resuscitation is complicated in
hypotensive septic
patients by their susceptibility to
pulmonary edema . -
pubmed
This problem was evaluated in the
ovine model of
endotoxemia with a
chronic lung lymph fistula . -
pubmed
Central penetrating excisional
wounds were made in the corneas of 12
rabbits and 10
trout . -
pubmed
The circadian pattern of intragastric acidity was assessed in 19 healthy subjects and 37
patients with active , endoscopically proven
duodenal ulcer using 24 - hr continuous intraluminal pH - metry . -
pubmed
The median pH 24 - hr profiles showed that
ulcer patients had lower postprandial pH elevations and a smaller decline in acidity during the early morning hours when compared with controls . -
pubmed
We conclude that the 24 - hr acidity is higher in
ulcer patients compared to healthy subjects and that the differences are particularly evident in the postprandial and nocturnal periods . -
pubmed
Those from
SLE patients with active disease produced significantly more than did those from
patients with inactive disease . -
pubmed
Ventricular tachycardia could no longer be induced in 7 ( 35 % ) of the 20
patients studied with combination therapy . -
pubmed
To prove the curve fitting to
tumour growth by the modified logistic function the total number of Ehrlich ascites
tumour cells was measured in 144
mice at 12 different times after inoculation . -
pubmed
The
abnormalities in conjugate eye movements observed after
cerebellar lesions are related to the abnormalities in movements of the extremities observed in the same
patients . -
pubmed
[ Comparative evaluation of titrometric and colorimetric methods of determination of
nonesterified fatty acids "
NEFA " in the blood serum of
diabetic patients ] . -
pubmed
Influence of
fluoride and
phosphate on
alveolar bone loss in the
rat . -
pubmed
[ Evaluation of the myelograms in
acute leukemias in
children treated at the District Special Hospital for Children in Opole during 1962 - 1964 ] . -
pubmed
Cellular
cytotoxicity of C57BL/6 adult
mice peritoneal cells to xenogeneic ( Chang liver ) and
syngeneic ( BL / 6 - WT3 ) herpes simplex virus ( HSV )- infected cells was analyzed in a 6 - h 51Cr release assay . -
pubmed
There was no natural killer
cytotoxicity to targets with cells from uninfected
mice except at very high effector cell ratios . -
pubmed
HSV - infected ( 2 X 10(4 ) PFU intraperitoneally 1 day previously )
mice mediated significantly higher antibody - dependent cellular
cytotoxicity and required less antibody ( 10(-5 ) versus 10(-2 ) dilution ) , fewer cells , and less time to kill than cells from uninfected
mice . -
pubmed
HSV - infected
mice mediated natural killer
cytotoxicity but preferentially killed syngeneic HSV - infected cells . -
pubmed
Stimulation of
cytotoxicity was not virus specific since
influenza - infected
mice mediated similar levels of cytotoxicity to HSV - infected targets . -
pubmed
The true diagnoses in the thirteen patients were :
glioma in three ;
meningioma ,
brain abscess ,
epilepsy and
subdural haematoma in two
patients each ; hepatic
coma and
syringobulbia in one patient each . -
pubmed
Combined oral and nasal
beclomethasone diproprionate in
children with
atopic eczema : a randomised controlled trial . -
pubmed
In a double blind , placebo controlled , crossover trial in 26
children with severe
atopic eczema those receiving four weeks ' treatment with combined oral plus nasal
beclomethasone diproprionate improved significantly more than those receiving placebo . -
pubmed
Of 12 adult
patients with high - grade
soft tissue sarcoma receiving adjuvant chemotherapy and at risk for 36 - 84 months , 9 ( 75 % ) remain
metastasis free and 10 ( 83 % ) have adequate local disease control with limb preservation . -
pubmed
Hypermetabolic doses of
levothyroxine sodium produced remissions in five of seven
women with intractable
manic - depressive illness who were followed up for nine months to nine years . -
pubmed
In
hyperthyroid subjects , the serum levels of total and free
cholesterol were significantly lower than in normal
subjects and the fractional
lecithin :
cholesterol acyl transfer rate was significantly higher than in normal subjects . -
pubmed
The free
cholesterol / total
cholesterol ratio in
hypothyroid females and the serum levels of
triglyceride and
free fatty acid in
hypothyroid male were significantly higher than in normal subjects . -
pubmed
The fractional
lecithin :
cholesterol acyl transfer rates in
hypothyroid females were significantly lower than in normal females . -
pubmed
The dynamics of cell - mediated immunity indices in 83
patients with rectal
tumors who underwent surgery or received combined treatment ( preoperative radiation + surgery ) was followed . -
pubmed
METHODS : Thirty - three
patients had localization of a solitary
adenoma with
99mTc - sestamibi . -
pubmed
A novel mycoplasmal species designated as
Mycoplasma penetrans has been isolated recently from patients infected with
human immunodeficiency virus . -
pubmed
Dipole source analysis was carried out in three adults and four
children with 3 c / s generalized spike - wave ( SW ) discharges and
absence seizures . -
pubmed
Bone marrow and peripheral blood lymphocyte phenotype in
patients with
bone marrow failure . -
pubmed
However , the phenotype of immune effectors in the marrow of
AA patients remains unknown . -
pubmed
We examined severe ( sAA ) and moderate
AA ( mAA )
patients and compared them to healthy volunteers and patients with
myelodysplastic syndrome (
MDS ) . -
pubmed
Helminthic infestation complicated by
intussusception in baboons (
Papio hamadryas ) . -
pubmed
This
helminth is well - recognized as a cause of
intussusception in
human infants , but the complication has not been reported previously in non -
human primates . -
pubmed
Then , in two separate experiments , endotoxin - induced
uveitis was produced in a total of 48
mice by injecting
Salmonella typhimurium endotoxin into one hind footpad . -
pubmed
Electron microscopic identification of parvovirus virions in erythroid and granulocytic - line cells in a patient with
human parvovirus B19 induced
pancytopenia . -
pubmed
In this short report we describe a patient with
human parvovirus B19 ( HPV B19)-induced transient
pancytopenia . -
pubmed
RESULTS :
Patients requiring pedal bypass were more likely to have
diabetes and
congestive heart failure but less likely to have a history of smoking . -
pubmed
Pedal bypass represented 21 % of our experience with infrapopliteal vein grafts for chronic limb - threatening
ischemia and was required more frequently in diabetic
patients . -
pubmed
Immune response in
mice infected with the attenuated
Japanese encephalitis vaccine strain SA14 - 14 - 2 . -
pubmed
A single immunization with SA(A ) significantly protected
mice against lethal intracerebral ( ic ) challenge with the virulent SA(V )
strain . -
pubmed
Two
patients are here reported with
metastatic MTC , who developed
CS two years after the
thyroid cancer was diagnosed . -
pubmed
A review is also made of clinical and biochemical characteristics of cases with
MTC associated with ectopic
CS reported in the literature and it is concluded that the cortico - adrenal function in follow - up should be monitored in
patients with this type of
cancer . -
pubmed
Acidic urine was also demonstrated in those
dogs with
B. - pubmed
Recognition of
drug side effects is vital for optimal
patient care , because early withdrawal of the offending agent and institution of appropriate treatment have the potential to significantly reduce the overall morbidity and mortality associated with the diagnosis of
cancer . -
pubmed
Zinc deficiency and the desaturation of
linoleic acid in
rats force - fed fat - free diets . -
pubmed
Additionally , in
zinc - deficient
rats there were changes of
( n-6 ) PUFA levels typical for impaired delta 5 and delta 6 desaturation :
linoleic acid and
dihomo - gamma - linolenic acid were elevated ;
arachidonic acid ,
docosatetraenoic acid , and
docosapentaenoic were lowered by
zinc deficiency . -
pubmed
Therefore , the study shows that
zinc deficiency impairs desaturation of
linoleic acid in
rats force - fed fat - free diets and therefore supports results from former convential
zinc deficiency experiments suggesting a role of
zinc for desaturation of
linoleic acid . -
pubmed
MATERIALS AND METHODS : Specific characterization and quantification of hemodynamic abnormalities of the cavernous arterial inflow and corporeal veno - occlusive mechanism associated with failure to respond to intracavernous pharmacotherapy were performed retrospectively in 69
patients with nonendocrinological
impotence . -
pubmed
PURPOSE : To determine the reliability and the measuring agreement between two radiologists in the identification of relevant structures of prostate anatomy in
patients with
prostate carcinoma . -
pubmed
PATIENTS AND METHOD : 15
patients with
prostate carcinoma proved by histology underwent MR Imaging on 1.5 Tesla MR - system ( Siemens Erlangen ) . -
pubmed
The case of a 47 - year - old
man surgically treated with Halsted mastectomy for
breast cancer and submitted to
Tamoxifen therapy for more than four years is reported . -
pubmed
Topical delivery of
keloid therapeutic drug ,
tranilast , by combined use of
oleic acid and
propylene glycol as a penetration enhancer : evaluation by skin microdialysis in
rats . -
pubmed
As with
intervertebral disc herniation in
children , an accurate diagnosis may be often delayed due to concerns for
neoplasm ,
infection , and
spondylolisthesis . -
pubmed
Hepatocellular carcinoma (
HCC ) is the major primary
malignant tumor in the
human liver , but the molecular changes leading to liver cell transformation remain largely unknown . -
pubmed
We then analyzed
human HCCs and found similar mutations in eight of 31 ( 26 % )
human liver tumors tested and in
HepG2 and
HuH6 hepatoma cells . -
pubmed
Intraarticular variability of synovial membrane histology , immunohistology , and cytokine mRNA expression in
patients with
rheumatoid arthritis . -
pubmed
CONCLUSION : Biopsies from the suprapatellar pouch , medial gutter , and cartilage - pannus junction will provide a representative sample of synovial membrane pathology in
patients with
rheumatoid arthritis . -
pubmed
Thrombotic microangiopathy in the
HIV-2 - infected macaque . -
pubmed
Thrombotic microangiopathy (
TMA ) has been increasingly reported in
human immunodeficiency virus ( HIV )- infected humans over the past decade . -
pubmed
We prospectively analyzed the renal pathology and function of 27
pigtailed macaques (
Macaca nemestrina ) , infected intravenously with a virulent
HIV-2 strain ,
HIV-2(287 ) , in addition to that of four uninfected control macaques . -
pubmed
Typical lesions of
human HIV - associated
nephropathy were undetectable . -
pubmed
Six of the 27
HIV-2 - infected macaques demonstrated both histological TMA lesions (
thrombi in glomerular capillary loops and small arteries , mesangiolysis ) and ultrastructural lesions ( mesangiolysis , subendothelial lucency , platelet
thrombi in glomerular capillary lumina ) . -
pubmed
Extrarenal
thrombi were detected in the gastrointestinal and adrenal microvasculature of
macaques that had developed
renal TMA . -
pubmed
In a retrospective analysis of kidneys obtained from 39 additional macaques infected with
HIV-2(287 ) , seven cases demonstrated
TMA . -
pubmed
In situ hybridization showed no detectable
HIV-2 RNA in kidney sections of 65/66
HIV-2 - infected macaques , including all 13
TMA cases . -
pubmed
The
HIV-2 - infected macaque may be a useful model of
human HIV - associated
TMA . -
pubmed
[ Ampli -
pulse phoresis in
patients with partial
optic nerve atrophy ] . -
pubmed
This assay would permit discrimination between those animals naturally infected with wild type BHV1 and those vaccinated with
tk - BHV1 strains . -
pubmed
In spite of this , analysis of
postoperative complications , line loss of the preoperative best spectacle corrected acuity and
patients satistaction shows that LASIK is a better method in correction of high
myopia by excimer laser . -
pubmed
Perinephric abscess due to
Aspergillus fumigatus . -
pubmed
Biventricular pacing has been proposed to resynchronize ventricular contraction in
patients with
congestive heart failure (
CHF ) and interventricular conduction delay . -
pubmed
A total of 15
patients ( 52 % ) had ICD
shocks and 6
patients ( 21 % ) had 113 episodes of
ventricular tachyarrhythmias , of which 96 ( 85 % ) were converted to sinus rhythm with antitachypacing . -
pubmed
Thus , ischemic
patients with reduced left ventricular ejection fraction and
ventricular tachyarrhythmias seem good candidates for biventricular pacing with ICD backup . -
pubmed
The
sudden death risk for those with
idiopathic dilated cardiomyopathy , however , is difficult to stratify , and the choice of ICD backup has to be considered on the basis of
patient safety , as well as of costs . -
pubmed
Gene therapy of
Parkinson ' s disease using adeno - associated virus (
AAV ) vectors . -
pubmed
Onychomycosis due to
Candida parapsilosis . -
pubmed
We report a case of
onychomycosis with
melanonychia due to
Candida parapsilosis alone . -
pubmed
Candida parapsilosis is now identified in the great majority of
candidal onychomycosis , mainly in association with other yeasts . -
pubmed
We present a case of intramedullary
spinal gangliocytoma in a 7 - year - old
girl who presented with
scoliosis and progressive
weakness of both legs . -
pubmed
EXEGESIS : We report four
patients with
Hashimoto ' s thyroiditis who presented neurological or
psychiatric features . -
pubmed
Cross - sectional studies involved parasitological examination and
anaemia evaluation before and at 10 months and 15 months after
schoolchildren were dewormed . -
pubmed
Attributable fraction analysis suggested that
hookworm and
schistosomiasis were responsible for 6 % and 15 % of
anaemia cases , respectively . -
pubmed
The complex pathophysiology of
chronic kidney disease alters the adaptations to
anaemia in
uraemic patients . -
pubmed
The increased cardiac output induced by
anaemia is associated with
left ventricular hypertrophy and
cardiac disease in renal
patients . -
pubmed
A total of 42
patients with suspected
CAD were studied . -
pubmed
Significant coronary narrowing ( & gt ; or = 50 %
luminal stenosis ) was detected by angiography in 22
patients . -
pubmed
At visual analysis , all
patients with
CAD ( & gt ; or = 50 %
luminal stenosis ) ( n-22 ) had an abnormal
99mTc tetrofosmin tomogram . -
pubmed
Nine out of 20
patients without significant coronary narrowing ( but with
tortuosis ,
atheromathosis , with
microvascular diseases ) showed abnormal findings . -
pubmed
Catecholamine levels in peripheral blood lymphocytes from
multiple sclerosis patients . -
pubmed
We studied peripheral blood lymphocytes from
MS patients . -
pubmed
The levels of
dopamine (
DA ) ,
norepinephrine ( NE ) ,
epinephrine ( E ) and their metabolites in extracts of lymphocytes from 58
MS patients and 19 healthy controls were measured by using capillary electrophoresis . -
pubmed
The
MS patients were divided into clinical subgroups : a laboratory - supported definitive ( first - attack )
MS group , and a relapsing - remitting ( RR ) group in remission . -
pubmed
The peripheral blood lymphocyte level of
epinephrine was significantly higher in the first - attack
MS patients ( p=0.028 ) than in the controls . -
pubmed
Local delivery of
nitric oxide from an eluting stent to inhibit neointimal thickening in a
porcine coronary injury model . -
pubmed
Morphometric analyses were performed in 16
pigs to determine the effect of
NO - eluting stents on
neointimal hyperplasia 28 days following
arterial injury . -
pubmed
Although local delivery of
NO from this device did not reduce
neointimal hyperplasia in this
porcine model , this polymer - coated stent might be a promising tool for administration of other agents that may modify the reparative tissue responses leading to restenosis . -
pubmed
There were no
intraoperative complications and no conversions , and postoperatively all
patients were started on a clear liquid diet on postoperative day 1 . -
pubmed
Four
patients were
pain free , whereas one
patient required intermittent narcotics at 1 - year follow - up . -
pubmed
[
Opportunistic infections in
HIV - positive patients hospitalized in the Clinic of
Infectious Diseases AMG ] . -
pubmed
Effects of
Melilotus officinalis on acute
inflammation . -
pubmed
Our study investigated the effects of
Melilotus officinalis L. extract , containing 0.25 %
coumarin , on acute
inflammation induced with oil of turpentine in male
rabbits . -
pubmed
In the bone marrow
acute phase response ,
M. - pubmed
OBJECTIVE : To evaluate the outcome of using radiotherapy ( RT ) alone to treat
patients with early - stage
Hodgkin ' s disease (
HD ) . -
pubmed
METHOD : The records of 28
patients with
HD treated with RT alone at Kuwait Cancer Control Center between 1980 and 1998 were reviewed . -
pubmed
Two
patients had B symptoms , 12 ( 42.9 % )
patients lymphocyte - predominant histology , 9 ( 32.1 % )
nodular sclerosis and 7 ( 25 % ) mixed cellularity . -
pubmed
PURPOSES : To retrospectively determine the factors influencing treatment decisions in older
breast cancer patients at a single center . -
pubmed
EXPERIMENTAL DESIGN : 216
patients age & gt ; or = 75 seen in post - treatment follow - up between January , 1997 and June , 2000 were identified in the Memorial Sloan - Kettering
breast cancer database . -
pubmed
CONCLUSION : We hypothesize that both comorbidity and age play a significant role in influencing treatment decisions in the older
breast cancer patient but these two variables are not necessarily correlated . -
pubmed
Postoperative complications due to
Staphylococcus aureus . -
pubmed
Optical mapping of the spread of excitation in the isolated
rat atrium during
tachycardia - like excitation . -
pubmed
We aimed to assess transmissibility of the
bovine spongiform encephalopathy (
BSE ) agent to
primates by the intravenous route and study its tissue distribution compared with
infection by the oral route . -
pubmed
Human iatrogenic
vCJD cases infected intravenously raise the same public - health concerns as primary cases and need the same precautionary measures with respect to blood and tissue donations and surgical procedures . -
pubmed
Participants included five
people without any
neuromuscular impairment . -
pubmed
Our study was undertaken to investigate whether
bacterial endotoxin / lipopolysaccharide ( LPS ) affects the neurogenic vasopressor response in
rats in vivo by presynaptic mechanisms and , if so , to characterize the type of presynaptic receptor(s ) operating in the initial phase of
septic shock . -
pubmed
Twelve intramuscular injections in six weeks led to significantly more
participants with a good overall therapeutic effect after one year , and to significantly better
pain reduction during one of two activities . -
pubmed
One trial ( 43
participants ) found that intramuscular injections of the anabolic
steroid nandrolone phenylpropionate significantly improved both
pain and function compared to placebo injections . -
pubmed
The criterion of qualification for the investigated group was medical history of a
patient , which revealed
climacteric symptoms and age of women ( from 45 to 60 years old ) . -
pubmed
[ Results evaluation of surgical treatment of
patients with
lower eyelid defects ] . -
pubmed
METHODS : Fifty - eight elderly
individuals were tested for
delayed - type hypersensitivity ( DTH ) responses to
Candida and
tetanus antigens . -
pubmed
CONCLUSIONS : An inverse relationship between
Candida DTH response and CIRS score suggests that increased
chronic disease burden is associated with diminished cell - mediated immune response . -
pubmed
A 22 - year - old Caucasian
patient underwent living - donor liver transplantation ( LDLT ) for
hepatic hemangioendothelioma in a healthy liver . -
pubmed
MATERIAL AND METHODS : The vascular systems of seven edentulous
human cadavers were flushed out and filled with either red - colored rubber bond or Indian ink and
formalin mixture . -
pubmed
INTRODUCTION :
Hepatitis C virus (
HCV ) has been implicated as a risk factor for the development of
diabetes mellitus , type 2 (
DM2 ) . -
pubmed
RESULTS : We found 13 % of
diabetics in the
patient with viral RNA , 9.3 % in the infected
patients without RNA and 3.9 % in the controls . -
pubmed
The presence of
HCV - antibodies showed a 2.78 odds ratio for
diabetes risk . -
pubmed
DISCUSSION : Our results showed a relationship between
HCV infection and
diabetes mellitus type 2 , so that the percentage of
diabetics increased parallelly with the degree of viral activity and the variable " presence of
HCV - antibodies " was the one that most contributed to the risk . -
pubmed
Although our results would support the role of the
iron metabolism in the development of
diabetes , follow - up studies of a cohort of patients infected by
HCV would be necessary to contrast this statement . -
pubmed
The treatment of
obesity in companion
animals frequently focuses on restriction of energy intake . -
pubmed
Musicogenic seizures can arise from multiple temporal lobe foci : intracranial EEG analyses of three
patients . -
pubmed
The ictal - onset zones in these
patients were then further localized using by intracranial EEG monitoring , and the outcomes of the two
patients who underwent
epilepsy surgery were determined . -
pubmed
RESULTS :
Patient 1 's musicogenic
seizures localized to the right lateral temporal lobe ,
patient 2 's originated in the right mesial temporal lobe , and
patient 3 's arose independently from both mesial temporal lobes . -
pubmed
Patients 1 and 2 underwent resective
epilepsy surgery and are
seizure free ( Engel class I ) . -
pubmed
Patients with medically intractable
musicogenic epilepsy and with unilateral ictal onset zones may be considered candidates for resective
epilepsy surgery . -
pubmed
Twenty - two
subjects were examined in normoxia ( 21 %
O2 ) , after 16 hours passive exposure to normobaric
hypoxia ( 12 %
O2 ) corresponding to a simulated altitude of 4,500 m and after 6 hours recovery in normoxia . -
pubmed
Clinical
AMS was diagnosed in 50 % of
subjects during
hypoxia and corresponding
headache scores were markedly elevated ( P<0.05 versus non - AMS ) . -
pubmed
All treatments currently approved for
AD have moderate efficacy in slowing the rate of
cognitive decline in
patients , and no efficacy in halting progression of the disease . -
pubmed
After long - term therapy , some
patients with
systolic heart failure (
HF ) display improved left ventricular ( LV ) function over time , a response that is associated with improved long - term outcomes . -
pubmed
To investigate predictors of improved LV function in an ethnically diverse
HF cohort , we selected 71
patients with
HF who had baseline ejection fractions ( EF ) & lt;40 % , follow - up EFs & gt ; or = 50 % , and & gt;20 % increases on follow - up echocardiography performed & gt ; or = 6 months later . -
pubmed
In conclusion , patients with
hypertensive causes of
HF are more likely to demonstrate improved LV function over time than
patients with ischemic causes of
HF . -
pubmed
RESULTS : The biopsy results were normal in 78
patients , scant atypical and malignant cells in 30 ,
carcinoma with treatment effect in 43 , and
carcinoma without treatment effect in 13 . -
pubmed
Anti -
ulcer activity of
Adhatoda vasica Nees . -
pubmed
Adhatoda vasica Nees ( Acantheceae ) , commonly known as Vasaka , is a well - known plant in indigenous systems of medicine and is used for its beneficial effects , particularly in
bronchitis . -
pubmed
The present investigation was carried out to study the anti -
ulcer activity of
Adhatoda vasica leaves using two
ulcer models ( 1 )
Ethanol - induced , and ( 2 ) Pylorus ligation plus
aspirin - induced models . -
pubmed
Adhatoda vasica leaf powder showeda considerable degree of anti -
ulcer activity in experimental
rats when compared with a control . -
pubmed
Results of the study suggest that in addition to its classically established pharmacological activities , the
plant also has immense potential as an anti -
ulcer agent of great therapeutic relevance . -
pubmed
Plasmablastic cytomorphologic features in
plasma cell neoplasms in immunocompetent patients are significantly associated with
EBV . -
pubmed
Multiple myeloma (
MM ) is rarely associated with
Epstein - Barr virus (
EBV ) irrespective of
HIV status , in contrast with its morphologic mimic ,
plasmablastic lymphoma , which occurs mainly in immunocompromised patients with frequent
EBV association . -
pubmed
The
patient with
plasmacytoma was disease free for 75 months , and the remaining 3
patients with
MM died at 15 , 74 , and 97 months , respectively ; the median survival of
patients with
EBER - MM was 12 months . -
pubmed
EBV+
tumors were associated with plasmablastic cytomorphologic features and high labeling indices . -
pubmed
These
tumors may have been driven by
EBV to gain the plasmablastic cytomorphologic features and high proliferation fraction . -
pubmed
A large cohort study is needed to clarify the prognostic impact of
EBV on immunocompetent
patients with
MM . -
pubmed
CONCLUSIONS : Contrast - enhanced CT scanning results in superior diagnostic precision in
patients with acute
abdominal pain . -
pubmed
Finally , we demonstrate an inverse relationship between
AS and gene duplication , suggesting that the latter may be primarily responsible for the emergence of new functional transcripts in
nematodes . -
pubmed
No inverse
hypopyon was observed in any of
patients . -
pubmed
CONCLUSIONS :
Silicone oil emulsification may develop earlier than expected in
patients with
nystagmus who underwent pars plana vitrectomy combined with
silicone oil injection . -
pubmed
Prenatal
choline supplementation attenuates neuropathological response to
status epilepticus in the adult
rat hippocampus . -
pubmed
Prenatal
choline supplementation ( SUP ) protects adult
rats against spatial
memory deficits observed after
excitotoxin - induced
status epilepticus (
SE ) . -
pubmed
To determine whether the tyrc allele was directly responsible for the response to selection , we examined B6
mice that have a mutant tyr allele ( tyr(c-2j- ) ) and an AJ congenic
strain that has the wild - type B6 allele for tyr . -
pubmed
Multigenic factors associated with a
hydrocephalus - like phenotype found in inter - subspecific consomic
mouse strains . -
pubmed
Hydrocephalus is a significant clinical condition in
humans and is known to be a multifactorial
neurologic disorder . -
pubmed
By analyzing breeding records of a panel of inter - subspecific consomic
mouse strains , we found that consomic
strains with MSM / Ms ( MSM ) chromosomes 4 , 5 , 7 , 11 , 15 , and 17 showed a significantly higher incidence of
hydrocephalus , whereas both parental
strains , MSM and C57BL/6J ( B6 ) , rarely showed this abnormality . -
pubmed
Of these ,
post - stroke hyperglycaemia (
PSH ) is the most frequently recognised abnormality and is documented in up to 50 % of
patients at the time of
stroke presentation . -
pubmed
Importantly , a significant proportion of
hyperglycaemic acute stroke patients ( approximately 50 % ) have undiagnosed
disorders of glucose metabolism , including
diabetes . -
pubmed
Animal and
human data have repeatedly demonstrated that PSH negatively impacts upon the fate of ischaemic brain tissue , with greater
infarct growth , higher mortality and more severe disability being consistent findings amongst
hyperglycaemic stroke subjects . -
pubmed
The airway
NO flux and alveolar
NO concentration can be elevated in adults and
children with
asthma and have been correlated with markers of
airway inflammation and
airflow obstruction in cross - sectional studies . -
pubmed
Number of studies have shown a high prevalence of
patent foramen ovale (
PFO ) in
patients with
migraine , especially
migraine with aura . -
pubmed
Furthermore
patients with
PFO and
migraine also show a marked improvement in their symptoms after percutaneous closure of the
PFO . -
pubmed
We clinically evaluated seven
individuals with
HGPPS from five previously unreported consanguineous families . -
pubmed
All affected
individuals had severe
horizontal gaze restriction , progressive
scoliosis , and
lower brainstem hypoplasia on neuroimaging , the hallmarks of this
syndrome . -
pubmed
One
individual experienced
head trauma with a
right subdural hematoma associated with a
right hemiparesis , observations that confirm clinically for the first time that corticospinal tracts in
HGPPS are uncrossed . -
pubmed
METHODS : 513
APL patients in the last two decades were retrospectively analyzed in this research . -
pubmed
RESULTS : The median age of the
APL patients was 33 years old and the ratio of male and female was 1.21:1 . -
pubmed
CONCLUSIONS : Comprehensive evaluation of MICM could be of important significance in the diagnosis and prognosis judgment for
APL patients . -
pubmed
Over a period of 18 years , 17
patients with proven
Langerhans cell histiocytosis (
LCH ) were treated at the Haematological Clinic in Brno . -
pubmed
In 13 of them , the disease was diagnosed at adult age , and 4
patients were referred to the centre with
LCH diagnosed at early child age . -
pubmed
One of these 4
patients suffered from repeated
recurrences of the disease at adult age and was diagnosed with progressive
neurodegenerative damage of the CNS at the age of 25 which in its terminal phase resulted in the patient 's immobility ,
loss of sphincter control , incapacity to communicate and
death at the age of 32 . -
pubmed
LCH was diagnosed at adult age in 13
patients . -
pubmed
Only 2 of 13
patients ( 15 % ) had multiple
bone lesions upon diagnosis , the remaining 6
patients ( 46 % ) had only one lesion at the time of diagnosis . -
pubmed
Repeated
recurrence of bone involvement was only recorded in 3 out of 13
patients ( 23 % ) . -
pubmed
The combination of recurrent bone involvement and the development of lung affection (
dyspnoea ,
irritating cough ,
nodularities and
cysts in HRCT images ) were documented in 2 out of 13
patients ( 15 % ) . -
pubmed
One of the
patients diagnosed with
LCH at the age of37 had repeated
recurrence of
bone involvement , which was also treated by 2 cycles of high - dose chemotherapy and autologous transplantation . -
pubmed
Primary extraoseal ( extamedular ) involvement was diagnosed in 5 out of 13
patients ( 38 % ) (
mandibular gum infiltration , single cervical node infiltration , hand skin infiltration , infiltration of the perineal region and infiltration of the hypophysial infundibular and primary lung form of
LCH ) . -
pubmed
In the 3rd case , the first sign ofthe disease was
diabetes insipidus in a 34 - year - old
man , and an infiltrate in the anal region similar to
condylomata acuminata . -
pubmed
LCH pulmonary involvement should be considered in
patients with an interstitial pulmonary process and the examinations should be focused accordingly ( thoracoscopy with sampling for histological exams or bronchoalveolar lavage ) plus the indispensable immunohistochemical examination . -
pubmed
Mounting evidence from clinical and basic research suggests that
estrogen signaling may be altered in the brains of
people with
schizophrenia . -
pubmed
338
patients with probable
AD were treated with
ChEis (
donepezil ,
rivastigmine and
galantamine ) as per the clinician 's judgment and were observed for nine months . -
pubmed
Patients were grouped in three different categories (
patients not
depressed and not treated with SSRIs ,
patients depressed and treated with SSRIs , and
patients depressed but not treated with SSRIs ) . -
pubmed
The mean change in MMSE score from baseline to nine months showed that
depressed patients not treated worsened in comparison with those not
depressed and not treated with
SSRIs ( mean change -0.8 + /- 2.3 vs 0.04 + /- 2.9 ; p = 0.02 ) and
patients depressed and treated with
SSRI ( mean change -0.8 + /- 2.3 vs 0.1 + /- 2.5 ; p = 0.03 ) . -
pubmed
CONCLUSIONS : In
AD patients treated with AChEIs ,
SSRIs may exert some degree of protection against the negative effects of
depression on cognition . -
pubmed
Adalimumab for
psoriasis patients who are non - responders to etanercept : open - label prospective evaluation . -
pubmed
OBJECTIVES : To assess the efficacy and safety of
adalimumab ( 40 mg weekly ) in
psoriasis patients who were non - responders to high - dosage
etanercept ( 50 mg twice weekly ) . -
pubmed
METHODS : All
patients attending a tertiary referral service for severe
psoriasis who were non - responders to high - dosage
etanercept [ i.e. -
pubmed
CONCLUSIONS : Initial data from this open - label prospective evaluation suggests that weekly
adalimumab therapy is an effective treatment for
patients with severe
psoriasis who had failed to respond to at least 3 months of high - dosage
etanercept . -
pubmed
METHODS : Thirty - eight end - stage
chagasic achalasia patients submitted to esophagectomy and cervical gastric pull - up were followed prospectively for a mean of 13.6 + /- 9.2 years . -
pubmed
Results from pivotal registration trials in major
depressive disorder cohere with outcomes from effectiveness studies indicating that the majority of
individuals receiving single - agent pharmacotherapy fail to achieve and sustain symptomatic remission . -
pubmed
The data from the studies reviewed herein also indicate that
quetiapine XR poses a low risk for extrapyramidal side effects in middle - aged and elderly
individuals with major
depressive disorder . -
pubmed
These recommendations were challenged recently by results of the Perioperative Ischemic Evaluation ( POISE ) , a large randomized trial of extended - release
metoprolol succinate started immediately before noncardiac surgery in
patients at high risk for
atherosclerotic disease . -
pubmed
The diagnosis of this disease can be performed through ultrasounds , but the molecular diagnosis offers some advantages , such as the early detection of asymptomatic
individuals who carry this
genetic defect , in order to perform a preventive monitoring and genetic counselling . -
pubmed
In this work , we present the results of the clinical analysis of 48
patients diagnosed with
autosomal dominant polycystic kidney disease . -
pubmed
The
arterial hypertension was the most frequent clinical manifestation of the disease in our study by what this entity should be included in all the
hypertense patients of unknown etiology and on the other hand , the infectious complications should be a sign of alert in every
patient with
polycystic kidney disease . -
pubmed
Use of computed tomography for cervical spine clearance in
trauma patients . -
pubmed
The need exists to strengthen the capacity of religious congregations to teach about HIV /
AIDS and target non - religious youth with
HIV transmission and prevention information . -
pubmed
Anti-(+)-
methamphetamine monoclonal antibody antagonists designed to prevent the progression of
human diseases of
addiction . -
pubmed
Clinical trials of reperfusion therapies for acute
ischemic stroke patients in an extended time window have shown mixed results . -
pubmed
OBJECTIVES : The aim of this study is to investigate the presence and the features of ToM decay in early
Alzheimer ' s disease (
AD )
patients compared to healthy controls adopting a neurodevelopmental stance . -
pubmed
METHOD : Sixteen
AD patients and 16 healthy controls were submitted to an increasing complexity ToM battery , tapping ToM precursors , standard first- and second - order false beliefs and advanced ToM tasks ( Eyes Test and strange stories ) . -
pubmed
CONCLUSION : This study identifies a specific pattern of deterioration in ToM abilities in
AD patients , following backwards developmental steps typical of the acquisition of mentalizing abilities , where the most complex ToM levels are impaired , whereas the intermediate and the simplest ones are preserved . -
pubmed
We detail the clinical course of a
patient with
peripheral vascular disease and indwelling superficial femoral artery stent , who developed stent
thrombosis in the 2 - week period between his last clinic visit and date of surgery , with no change in symptoms . -
pubmed
Based on intravascular ultrasound findings , it appears that
coronary artery spasm promotes negative arterial remodeling , suggesting that
patients with
coronary artery spasm might be at higher risk of accelerated
coronary atherosclerosis . -
pubmed
We report the cases of 3
patients with
ventricular arrhythmia secondary to
coronary artery spasm complicated by accelerated
coronary atherosclerosis . -
pubmed
Consequently ,
coronary disease progression should be considered in the case of
angina pectoris recurrence in
patients with
coronary artery spasm , especially in those with
coronary artery spasm complicated by
ventricular arrhythmia . -
pubmed
A total of 25
patients had a history of
CAD ( 15 % ) . -
pubmed
The CCA diameters of
patients with
CAD were significantly higher than those of
patients without
CAD ( 7.9 + /- 1.0 mm and 7.4 + /- 0.9 mm ; p = 0.01 ) . -
pubmed
Receiver operating characteristic curve of boundary value of CCA diameter revealed an area under the curve to identify the
patients with
CAD ( 0.63 , p = 0.04 ) . -
pubmed
As free - living
Gerbillus nanus show a relatively low
flea infestation , we hypothesized that this host uses an induced strategy and , consequently ,
flea infestation would not impose a long - term effect on energy metabolism . -
pubmed
Thus , the hypothesis that
flea infestation does not have a long - term effect on energy metabolism was supported , as was the idea of an induced over a constitutive immune response by
G. - pubmed
Thus ,
aspirin prodrugs effectively inhibit
human platelet aggregation and as such may be an alternative to conventional
aspirin . -
pubmed
In this paper , we will review the current knowledge about familiality of
LPL /
WM and provide novel data on
solid tumors and
myeloid malignancies in first - degree relatives of
LPL /
WM patients . -
pubmed
A number of bioactive compounds generally obtained from terrestrial
plants such as
isoflavones ,
diosgenin ,
resveratrol ,
quercetin ,
catechin ,
sulforaphane ,
tocotrienols and
carotenoids are proven to reduce the risk of
cardiovascular diseases and aid in cardioprotection which is the leading cause of
death globally . -
pubmed
UNLABELLED : The study was aimed to evaluate microvascular blood flow and theological blood properties in healthy
volunteers ( n = 27 ) and
patients with
cerebral accident ( n = 30 ) . -
pubmed
Thus , our results demonstrated the decrease of tissue perfusion , activization of vasodilating mechanisms , impaired blood rheology and the decrease of
oxygen supply to tissue in
patients with
cerebrovascular accident . -
pubmed
Annato extract and
beta - carotene modulate the production of reactive
oxygen species /
nitric oxide in neutrophils from
diabetic rats . -
pubmed
The present study was undertaken to evaluate the possible protective effects of annatto on the reactive
oxygen species and
nitric oxide (
NO ) inhibition in neutrophils from
alloxan - induced
diabetic rats . -
pubmed
Our results show that neutrophils from
diabetic animals produce significantly more reactive
oxygen species and
NO than their respective controls and that supplementation with
beta carotene and annatto is able to modulate the production of these species . -
pubmed
We describe here an unusual occurrence of
pseudoaneurysms in the common carotid and vertebral artery in a four - year - old
child victim of a
stab wound in the neck treated by parent
artery occlusion of the vertebral and common carotid arteries . -
pubmed
Individualized care for improved outcomes in
patients with
atrial fibrillation . -
pubmed
METHODS :
Rheumatoid arthritis (
RA )
patients who had taken CQ for at least 6 months and stable
CQ dosage for at least 2 months were included . -
pubmed
In
DU145 tumor bearing
mice , a single treatment of
tumor hyperthermia , induced via gold nanorod mediated plasmonic photothermal therapy , and intravenous administration of HSP targeted
HPMA copolymer -
docetaxel at 10mg / kg resulted in maintained
tumor regression for a period of 30 days . -
pubmed
Prevalence of
Pulmonary Tuberculosis Among
HIV Positive Patients Attending Antiretroviral Therapy Clinic . -
pubmed
RESULTS : This study showed 1012/172 ( 17 % ) prevalence of
pulmonary tuberculosis among
HIV positive patients , of which 87 ( 50.58 % ) were males and 85 ( 48.42 % ) were females . -
pubmed
CONCLUSION : The study showed that 17 % of
HIV infected persons had
tuberculosis co - infection . -
pubmed
The
infection biology of
Mycobacterium avium subsp . - pubmed
The prognosis is poor in
patients with positive
resection margins , high - grade
tumours and recurrent
tumours . -
pubmed
Transfusion of platelets treated ex vivo with
MG132 and washed before transfusion into
thrombocytopenic mice also reduced
carotid artery thrombosis . -
pubmed
Clumps of regenerants , from cotyledons and hypocotyls
ofPelargonium X hortorum seedlings , were inoculated with the disarmed
strain EHA101 ofAgrobacterium tumefaciens . -
pubmed
Evaluation of cerebrovascular reserve using
xenon - enhanced CT scanning in
patients with symptomatic
middle cerebral artery stenosis . -
pubmed
Cerebrovascular reserve ( CVR ) is an important prognostic factor in
patients with major
cerebral arterial steno - occlusive disease . -
pubmed
Twelve
patients with symptomatic
MCA stenosis were recruited . -
pubmed
Impaired CVR is an important characteristic of
patients with symptomatic
MCA stenosis . -
pubmed
We demonstrate that reduction of spliceosomal activity through loss of
peanuts promotes decondensation defects in
NC nuclei during mid - oogenesis . -
pubmed
Study of pharmacodynamic interaction of
Phyllanthus emblica extract with
clopidogrel and
ecosprin in
patients with
type II diabetes mellitus . -
pubmed
The effect of
vitamin C on
platelet aggregation in healthy and
coronary artery disease patients has been demonstrated . -
pubmed
MATERIALS AND METHODS : This was a randomized open label crossover study of 10
type II diabetic patients . -
pubmed
Further , the mean percent inhibition of
platelet aggregation was significant , when compared between single and multiple doses of
P. - pubmed
The fusion protein showed very low toxicity in
mouse experiments and impressive antitumor effects in a
Lewis Lung carcinoma model , with a 90 % cure rate . -
pubmed
Chronic pancreatitis and
systemic inflammatory response syndrome prevent impact of chemotherapy with
gemcitabine in a genetically engineered
mouse model of
pancreatic cancer . -
pubmed
BACKGROUND AND AIMS : BACKGROUND AND
AIMSGemcitabine is the standard therapy for
patients with
pancreatic cancer with
metastatic disease . -
pubmed
Genotoxic effects of commercial formulations of
Chlorpyrifos and
Tebuconazole on
green algae . -
pubmed
The alkaline single - cell gel electrophoresis assay ( comet assay ) was used for the study of the
genotoxic effects of insecticide
Chlorpyrifos and fungicide
Tebuconazole ( commercial formulations ) on two freshwater green algae species ,
Pseudokirchneriella subcapitata and
Nannocloris oculata , after 24 h of exposure . -
pubmed
Cardiovascular magnetic resonance using
oedema and
fibrosis imaging can early reveal , noninvasively and without radiation , heart involvement during
vasculitis , undetected by other imaging techniques and guide further risk stratification and treatment of these
patients . -
pubmed
Evaluation of early response to hepatic arterial infusion chemotherapy in
patients with advanced
hepatocellular carcinoma using the combination of response evaluation criteria in solid
tumors and
tumor markers . -
pubmed
METHODS : One hundred sixty - five
HCC patients treated with HAIC were reviewed retrospectively . -
pubmed
CONCLUSION : The use of the combination of RECIST and
tumor marker ratio could be useful for assessment of the early response to HAIC and prognosis of
patients with advanced
HCC . -
pubmed
We studied all
patients having a surgical revision in our center for a severe
bleb leak between January 1 and December 31 , 2008 . -
pubmed
In comparing the risk for a severe
bleb leak in younger ( below 55 y ) versus
patients aged 75 years or older , the odds ratio was 21.0 . -
pubmed
A trend was observed in which the
patients under the age of 55 years were at greater risk for a severe
bleb leak . -
pubmed
Human cervical cancer xenografts were established in
nude mice by transplantation of
HeLa cells , and the
tumors were then treated with psPEF . -
pubmed
This view has been called into question by the unexpected results of the
Human Genome Project which has painted a far more complex picture of the genetic features of
human disease than was anticipated . -
pubmed
The case of a 25 - year - old female
patient with
stage IV lung adenocarcinoma who developed fatal
ILD is reported here . -
pubmed
One month after treatment initiation , the
patient complained of continuous
dry cough and rapid progressive
dyspnea . -
pubmed
Forty one days after
icotinib treatment ,
icotinib associated
ILD was suspected when the
patient became increasingly
dyspnoeic despite of treatment of
pericardial effusion , left
pleural effusion and lower
respiratory tract infection , and X - ray computed tomography ( CT ) of chest revealed multiple effusion shadows and ground - glass opacities in bilateral lungs . -
pubmed
Forty three days after
icotinib treatment , the
patient died of
hypoxic respiratory failure . -
pubmed
To establish
vascular restenosis ,
rat carotid arteries were subjected to balloon angioplasty
injury . -
pubmed
BACKGROUND : The Collaborative Cross ( CC ) is a large panel of genetically diverse recombinant inbred
mouse strains specifically designed to provide a systems genetics resource for the study of complex traits . -
pubmed
This report is also the first to establish guidelines in defining and identifying
strain - specific splicing across different
mouse strains . -
pubmed
METHODS : This is a retrospective study of 460
systemic lupus erythematosus patients followed in a single rheumatologic center during the last 10 years . -
pubmed
Patients with
lymphopenia had more
leukopenia ( OR=1.8 ; 95 % CI=1.01 - 3.29 ) and lupus anticoagulant antibodies ( OR=2.2 ; 95 % CI=1.16 - 4.39 ) and those with
thrombocytopenia had more
leukopenia ( OR=3.1 ; 95 % CI=1.82 - 5.44 ) and
antiphospholipid syndrome ( OR=3.1 ; 95 % CI=1.28 - 7.87 ) . -
pubmed
Hepatic Lesions Caused by Large Granular Lymphocyte
Leukemia in Fischer 344
Rats : Similar Morphologic Features and Morphogenesis to Those of Nodular Regenerative
Hyperplasia (
NRH ) in the
Human Liver . -
pubmed
To characterize the
hepatic lesions in
Fischer 344 ( F344 )
rats afflicted with large granular lymphocyte ( LGL )
leukemia , the livers of
rats with
LGL leukemia at various stages were examined histopathologically and immunohistochemically . -
pubmed
The morphologic features in the livers of
rats afflicted with
LGL leukemia were diffuse , uniform - sized , granular , or micronodular lesions consisting of hepatocytes showing centrilobular
atrophy and
perilobular hypertrophy (
CAPH ) without
fibrosis . -
pubmed
With progression in the stage of the
LGL leukemia , the severity of the CAPH of hepatocytes increased resulting in fatty change and/or single - cell
necrosis , along with compensatory
hyperplasia of the hepatocytes , finally resulting in lesions similar to those seen in nodular regenerative
hyperplasia (
NRH ) in the
human liver . -
pubmed
In addition , direct and/or indirect
hepatocellular injuries by
leukemia cells were considered to be necessary for the formation of
human NRH - like lesions . -
pubmed
Morphogenetic investigation of the livers of
rats afflicted with
LGL leukemia may be helpful to clarify the pathogenesis of
NRH in the
human liver . -
pubmed
Dental caries is a widely prevalent
infectious disease afflicting the
humans worldwide . -
pubmed
However availability of review articles regarding
triphala as an antimicrobial against
oral infections is limited . -
pubmed
The present article reviews the use of
triphala and its constituents in the prevention and control of
dental caries and other common
oral infections . -
pubmed
Thorough review of the literature indicated that
triphala can be effectively used to manage dental
caries ,
gingival and periodontal diseases . -
pubmed
CASE PRESENTATION : A 54 - year - old Chinese
woman with a history of
diffuse large B - cell lymphoma in her first complete remission developed
peripheral neuropathy and
tracheal asphyxia . -
pubmed
We examined
patients with incidental
hemangiomas who received anti - angiogenic agents for the treatment of other
malignancies . -
pubmed
Our study population consisted of 17
colorectal cancer patients and one
lung cancer patient carrying 21
hemangiomas who received
bevacizumab , and seven
renal cell carcinoma patients carrying nine
hepatic hemangiomas who received
sunitinib . -
pubmed
METHODS : The study enrolled 44 prepubertal
children ( between 2 and 12 years of age ) with
thinness grades of 1 - 3 and 41 healthy age- and gender - matched
children . -
pubmed
Aortic rupture after thoracic endovascular repair in a
patient with
familial thoracic aortic aneurysm and
dissections type 6 (
FTAAD6 ) . -
pubmed
CONCLUSIONS : Lower WM integrity in
MMT patients may add to neurobiological factors associated with
relapse to
heroin use . -
pubmed
OBJECTIVE : Determine the effectiveness of in vitro maturation of oocytes in the
infertility treatment in high altitude
women with
polycystic ovaries . -
pubmed
PARTICIPANTS :
Women with
polycystic ovaries and
infertility . -
pubmed
INTERVENTIONS : there were 11
women from locations above 7,546 feet above sea level with
polycystic ovaries and
infertility in which were performed in vitro maturation of oocytes , followed by intracytoplasmic sperm injection , culture and embryo vitrification . -
pubmed
CONCLUSIONS : In vitro maturation of oocytes is an effective technique in the
infertility treatment of high altitude
women with
polycystic ovaries . -
pubmed
METHODS : In this prospective study , 60
patients ( of either sex ) with
chronic suppurative otitis media inactive mucosal disease were divided into 2 groups ( 30 in each ): group A comprised paediatric
patients aged 5 - 8 years and group B consisted of older
individuals aged over 14 years . -
pubmed
Focus on the prophylaxis , epidemiology and therapy of
methicillin - resistant
Staphylococcus aureus surgical site infections and a position paper on associated risk factors : the perspective of an Italian group of surgeons . -
pubmed
We report the case of a 47 - year - old
woman whose primary
mediastinal leiomyoma was incidentally found during evaluation of her persistent
cough . -
pubmed
This is a prospective cohort study of 7,216
patients with clinically manifest
arterial disease in the Secondary Manifestations of
Arterial Disease Study . -
pubmed
spinosa Co121 increased 77.13 % , from 310.44 + - 21.84 mug / mL in the initial fermentation medium ( with
glucose as the main
carbon source ) to 549.89 + - 38.59 mug / mL in a new optimized fermentation medium ( 98.0 g of
mannitol , 43.0 g of
cottonseed flour , 12.9 g of
corn steep liquor , 0.5 g of
KH2PO4 , and 3.0 g of
CaCO3 in 1 L of
H2O ; pH was adjusted to 7.0 before autoclaving ) . -
pubmed
CONCLUSIONS : The optimized fermentation medium developed in this study can probably be used to improve
spinosad production in screening industrial
strains of
S. - pubmed
Mantle cell lymphoma (
MCL ) is a highly chemo - refractory
tumor with generally poor outcome , especially if the
patients develop resistance to frontline drugs . -
pubmed
METHODS : A retrospective cohort study using the Taiwan National Health Insurance claims database was conducted to examine the risks of
HHF among newly diagnosed
type 2 diabetic patients who initiated
glinide ,
sulfonylurea , or
acarbose therapy during 2006 - 2012 . -
pubmed
CONCLUSIONS : These findings indicated that , as compared with
acarbose , glinide may be associated with a higher risk of
HHF for
type 2 diabetic patients . -
pubmed
To understand the molecular mechanisms behind the
LE apricot phenotype , comparative transcriptomes of
Prunus armeniaca L. were sequenced using Illumina HiSeq 2500 . -
pubmed
Most
vertebrates show
concussion responses when their heads are hit suddenly by heavy objects . -
pubmed
Although , preoperative modalities like computed tomography , magnetic resonance image and serology generally help in establishing the diagnosis , but
hydatid cysts with unusual localizations and atypical imaging findings may complicate the diagnosis and need be considered in the differential diagnosis of all cystic masses in all anatomic locations , especially in endemic areas , so as to reduce the
patient morbidity and mortality . -
pubmed
Imaging
children , especially with
developmental disorders , requires extra considerations related to
hyperactivity ,
anxiety and the ability to perform and maintain attention to the fMRI paradigm . -
pubmed
Methods : Initial clinical presentations including psychiatric symptoms , treatment details , and outcome with respect to psychiatric symptoms were collected from medical case records of
children aged less than 18 years with seropositive NMDAR
encephalitis from a single tertiary care center ( May 2010 - November 2016 ) . -
pubmed
All 21
children presented with
psychiatric symptoms at initial presentation . -
pubmed
In addition to psychiatric symptoms , at least 1 of the following was also seen in all
children :
speech disturbance ( 85.7 % , n = 18 ) ,
seizure ( 85.7 % , n = 18 ) , or
movement disorder ( 76.2 % , n = 16 ) . -
pubmed
A comorbid
psychiatric diagnosis ( ICD-10 criteria ) was made in 11
children ( 52.4 % ) ; the most common was
organic mood disorder ( n = 6 ) . -
pubmed
Three of the 4
children with residual
psychiatric symptoms and persistent academic difficulties were prepubertal . -
pubmed
Disease progression occurred in 44/108 ( 40.7 % )
patients and 13/108 ( 12 % )
patients died . -
pubmed
The median progression - free survival was 11.2 years , and as more than 80 % of
patients were alive 10 years after metastatic
breast cancer diagnosis . -
pubmed
Disease progression occurred in 4 of the 27
patients after the interruption of
trastuzumab treatment . -
pubmed
This case highlights the importance of recognizing mechanisms other than
heart block as a cause of
sudden death in a
patient with
KSS . -
pubmed
Patients with
vitreomacular traction ( VMT ) syndrome without a full - thickness
macular hole were included if they received an intravitreal injection ( IVI ) of
ocriplasmin . -
pubmed
We were able to combine them into a formula , ultimately allowing the calculation of an individual probability of treatment success with
ocriplasmin in
patients with
VMT syndrome without
FTHM . -
pubmed
The approach could yield anatomical hypotheses about brain connectivity , motivate rational strategies for treating
mood disorders with deep brain stimulation , and could be extended to
animal studies that use combined optogenetic fMRI . -
pubmed
BACKGROUND :
Post - operative nausea and vomiting (
PONV ) is one of the most important causes of
patient discomfort after laparoscopic surgeries despite the use of a multimodal pharmacological approach . -
pubmed
This study assessed whether the addition of
aprepitant to a multimodal regimen would further decrease the incidence of
PONV in high - risk
patients . -
pubmed
METHODS : Apfel - score three or four
patients , scheduled for laparoscopic procedures to treat
abdominal or pelvic cancer , were randomized to receive oral starch ( control group ) or 80 mg of oral
aprepitant ( treatment group ) before induction of anaesthesia in a double - blind study . -
pubmed
Vomiting occurred in 13/32 ( 40.6 % )
patients in the control group and in 1/34 ( 2.9 % )
patients in the treatment group ( P = 0.0002 , 95%CI : 18 - 54 % ) in the first 24 h after anaesthesia . -
pubmed
Adolescent Synthetic
Cannabinoid Exposure Produces Enduring Changes in
Dopamine Neuron Activity in a
Rodent Model of
Schizophrenia Susceptibility . -
pubmed
Background : Epidemiological studies recognize cannabis intake as a risk factor for
schizophrenia , yet the majority of
adolescents who use marijuana do not develop
psychosis . -
pubmed
Methods : We recently developed a novel
rodent model of
schizophrenia susceptibility , the F2
methylazoxymethanol acetate rat , where only a proportion ( ~40 % ) of
rats display a
schizophrenia - like phenotype . -
pubmed
Results : Adolescent synthetic cannabinoid exposure significantly increased the proportion of susceptible
rats displaying a
schizophrenia - like
hyperdopaminergic phenotype after puberty without producing any observable alterations in control
rats . -
pubmed
Conclusions : Taken together , these studies provide experimental evidence that adolescent synthetic cannabinoid exposure may contribute to
psychosis in susceptible
individuals . -
pubmed
LC - HRMS determination of
piperine on
rat dried blood
spots : A pharmacokinetic study . -
pubmed
Lenalidomide at the dose of 25 mg every other day in
patients affected by
multiple myeloma and
renal failure : a real - life experience . -
pubmed
Renal impairment (
RI ) is a relevant complication of
patients affected by
multiple myeloma (
MM ) ; it can be present in up to 30 - 35 % of newly diagnosed
MM and is linked to a poor outcome . -
pubmed
Dose reduction is mandatory in
RI ; however , there is no theoretical assumption against the possibility that protracting the time of full standard doses can be equally effective and tolerated by
patients requiring reduced doses . -
pubmed
In this report , we describe our retrospective experience , in 18
patients , with the administration of
lenalidomide 25 mg every other day for
patients with
MM and
RI . -
pubmed
It is known that the prevalence of
thyroid disease is higher among diabetic
patients than in general population . -
pubmed
Therefore , we conclude that the treatment with MSC was able to reverse the increased thyroid
H2O2 generation in
diabetic animals and in
PCCL3 cells exposed to high
glucose , an effect probably mediated by EV produced by these cells , acting in a paracrine fashion . -
pubmed
The in vitro
cytotoxicity effect of AgNPs showed promising anticancer activity against
human breast cancer MCF-7 cells . -
pubmed
MATERIAL AND METHODS : We analysed thirty
patients with
HCC for multiple clinic - pathological characteristics . -
pubmed
Metastatic Castration - Sensitive
Prostate Cancer : Optimizing
Patient Selection and Treatment . -
pubmed
Although
androgen - deprivation therapy ( ADT ) is still the backbone of treatment , the addition of
docetaxel or
abiraterone acetate has improved outcomes for
patients with
mCSPC and become standard of care . -
pubmed
With multiple treatment options available for
patients with
mCSPC , treatment selection to optimize
patient outcomes has become increasingly difficult . -
pubmed
Although surgery and/or radiation are standard of care for localized , intermediate- and high - risk
prostate cancer , these treatments are not routinely used as part of initial treatment plans for
patients with de novo
mCSPC . -
pubmed
Aneuploidy is associated with different
human diseases including
cancer . -
pubmed
Acute
toxoplasmosis and antioxidant levels in the liver , kidney and brain of
rats Toxoplasma gondii is a common protozoan parasite which causes
toxoplasmosis worldwide . -
pubmed
In 2011 and 2012 , 22 consecutive
patients with
cervical medullary syndrome and geneticist - confirmed
hereditary connective tissue disorder (
HCTD ) , with
Chiari malformation ( type 1 or 0 ) and
kyphotic clivo - axial angle (
CXA ) enrolled in the IRB - approved study ( IRB # 10 - 036 - 06 : GBMC ) . -
pubmed
Symptoms ,
patient satisfaction , and work status were assessed by a third - party questionnaire ,
pain by visual analog scale ( 0 - 10/10 ) , neurologic exams by neurosurgeon , function by Karnofsky performance scale ( KPS ) . -
pubmed
Two
patients returned to surgery for a superficial
wound infections , and two required transfusion . -
pubmed
All
patients who had rib harvests had
pain related that procedure ( 3/10 ) , which abated by 5 years . -
pubmed
The results support the literature , that open reduction of the kyphotic CXA to lessen
ventral brainstem deformity , and fusion / stabilization to restore stability in
patients with
HCTD is feasible , associated with a low surgical morbidity , and results in enduring improvement in
pain and function . -
pubmed
This study determined whether and how prenatal
hypoxia may cause malignant
hypertension and impaired vascular functions in spontaneous
hypertension rat ( SHR ) offspring at adolescent stage . -
pubmed
METHODS : A multicenter retrospective analysis was performed from March 2014 to April 2017 to assess 30- and 90 - day clinical cure and
adverse drug events ( ADEs ) in adult
patients who received & gt;= 1 dose of
dalbavancin for a non - ABSSSI indication . -
pubmed
At day 90 ,
relapse occurred in two
patients . -
pubmed
Three
patients had a potential
dalbavancin - associated
ADE : two patients with
renal dysfunction and one patient with
pruritus . -
pubmed
CONCLUSIONS : This study demonstrates a possible role for
dalbavancin in the treatment of non - ABSSSI invasive gram - positive
infections in select vulnerable OPAT
patients . -
pubmed
RESULTS : A total of 50
women with
uterine sarcoma were identified and
lesions included 43
leiomyosarcomas ( 86 % ) and seven high grade
sarcomas ( 14 % ) . -
pubmed
Thirty - nine
patients ( 78 % ) had a
recurrence : 22 had only metastatic
recurrence ( 58 % ) , two had isolated pelvic
recurrence ( 5 % ) and 15 had pelvic and metastatic
recurrence ( 38 % ) . -
pubmed
Results : Eight thousand eleven
diabetic patients and 1635 normal controls from 27 studies were included . -
pubmed
Characterization of Novel
Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys . -
pubmed
A variety of
animal models of
diabetes mellitus (
DM ) are required to study the genetics and pathophysiology of
DM . -
pubmed
The most commonly used plant families for
pneumonia and
tuberculosis therapy in the study region were Asteraceae , Bignoniaceae and
Fabaceae ( seven plants in each ) ; of these ,
Curcuma longa L. ,
Punica granatum L. and
Justicia adhatoda L. carried the most inhibiting potential against
Staphylococcus aureus and
Streptococcus pneumoniae while that of
Acalypha indica L. against
Mycobacterium tuberculosis . -
pubmed
BACKGROUND : The use , misuse and co - use of
alcohol , cannabis ,
tobacco , and other licit and illicit controlled substances has increased in past decades leading to higher rates of morbidity ,
overdose , and mortality in women of reproductive age . -
pubmed
This report is the first instance in which a
patient with severe
PAH , survived a successful
atrial septal defect (
ASD ) repair and bilateral lung transplantation during puerperium . -
pubmed
PATIENT CONCERNS : A 42 - year - old pregnant
woman with
congenital heart disease (
CHD ) and severe
PAH was admitted to our hospital for the management of pregnancy and delivery . -
pubmed
The
patient was diagnosed with severe
PAH in 2013 , and no significant improvements or deteriorations were found until this pregnancy - related hospital admission . -
pubmed
DIAGNOSIS : The
patient was diagnosed with
CHD and severe
PAH in 2013 with color Doppler echocardiography , right cardiac catheterization , and pulmonary perfusion imaging . -
pubmed
The
patient 's mean pulmonary arterial pressure increased to 140 mm Hg during pregnancy , suggesting an exacerbated
PAH with high risks to both her and the unborn
child . -
pubmed
Ginsenoside Rb1 , A Major
Saponin from
Panax ginseng , Exerts Protective Effects Against
Acetaminophen - Induced
Hepatotoxicity in
Mice . -
pubmed
Previous reports indicated
liver failure could be alleviated by
saponins (
ginsenosides ) from
Panax ginseng against
APAP - induced inflammatory responses in vivo . -
pubmed
CONCLUSIONS : Findings suggest that Korean
white - collar workers , particularly professionals , have elevated levels of
inflammation . -
pubmed
The
atopic dermatitis itch scale : development of a new measure to assess
pruritus in
patients with
atopic dermatitis . -
pubmed
Materials and methods : Six focus groups were conducted with 49 patients with
AD ( 32 adults ; 17
adolescents ) . -
pubmed
Three iterative rounds of cognitive debriefing interviews were conducted in 26 patients with
AD ( 17
adults ; 9
adolescents ) to pretest and refine the instrument . -
pubmed
Methods Professionally active
men aged 20 - 65 with
distal radius fracture were followed prospectively for 1 - year ( n = 88 ) . -
pubmed
Decreased FO prevents improvement of gait and muscle recovery and residual
LLD has a prominent influence on
patient satisfaction with THA , while few studies have investigated the relationship between FO and/or
LLD and
gait disturbances . -
pubmed
METHODS : We evaluated 92
patients ( including 20
patients who underwent gait analysis ) in whom total hip arthroplasty was performed for unilateral evere
osteoarthritis of the hip joint . -
pubmed
The
Glucose Lowering Effect of
Zornia gibbosa Span Extracts in
Diabetic Rats . -
pubmed
Materials and Methods : This
acute toxicity study was conducted for
ethyl acetate and
ethanol ( 70%v / v ) extracts of
Z. - pubmed
The anti - diabetic activity of selected
plant extracts were tested using
alloxan - induced
diabetes in a
rat model . -
pubmed
Zornia gibbosa significantly decreased
glucose concentrations and restored the altered enzymes levels caused by damage to different organs by
diabetes . -
pubmed
All
patients had mesh introduced through a 10 - 12 - mm port placed through the
ventral hernia defect . -
pubmed
Lameness ,
injuries , and cleanliness are considered important indicators of dairy
cow welfare , milk production , and milk quality . -
pubmed
A wide variation was detected in the true prevalence of the different
cow - based measurements among herds (
lameness : range = 19 - 72 % , median = 36 % ;
neck injuries : range = 0 - 65 % , median = 14 % ;
knee injuries : range = 0 - 44 % , median = 12 % ;
hock injuries : range = 0 - 57 % , median = 25 % ; dirty udder : range = 0 - 55 % , median 13 % ; dirty legs : range = 0 - 91 % , median = 18 % ; and dirty flanks : range = 0 - 82 % , median = 20 % ) . -
pubmed
Intraoperatively , the
patient suffered a
dural injury that was repaired . -
pubmed
Postoperatively , the
patient was electively ventilated for three days , continued with remote
cerebellar hemorrhage (
RCH ) treatment and precaution , and extubated on the third day as the
patient 's neurological function continued to improve . -
pubmed
Aloe vera : A medicinal plant used in skin
wound healing . -
pubmed
Skin injury is a major problem threatening
human physical and mental health , how to promote
wound healing has been the focus . -
pubmed
Many studies have shown that
Aloe vera plays an important role in promoting
wound healing . -
pubmed
Adding
Aloe vera to
wound dressing has become an ideal way . -
pubmed
This review will describe the process of
skin injury and
wound healing , and analyze the role of
Aloe vera in
wound healing . -
pubmed
In addition , the types of
wound dressing and the applications of
Aloe vera in
wound dressing will be discussed . -
pubmed
The hallmark of this unregulated inflammatory response includes
viral sepsis ,
pneumonitis shock ,
coagulopathy , and
acute respiratory distress syndrome (
ARDS ) which is the major cause of
death in
COVID-19 patients . -
pubmed
Hypervascular hepatic mass in a
patient with
breast cancer . -
pubmed
The protective effects of
trelagliptin on high - fat diet - induced
nonalcoholic fatty liver disease in
mice . -
pubmed
Nonalcoholic fatty liver disease (
NAFLD ) occurs in
patients with
type 2 diabetes mellitus (
T2DM ) . -
pubmed
In this study , we aimed to investigate the roles of
trelagliptin in the development of
NAFLD in a
mouse model . -
pubmed
To induce
NAFLD disease , C57BL/6
mice were fed a high - fat diet for 10 weeks . -
pubmed
A 56 - year - old
man presented at a local hospital with
nausea ,
vomiting ,
epigastric pain , and white stool . -
pubmed
aureus (
MRSA ) strains in in vitro models of
endophthalmitis . -
pubmed
An analysis of the occurrence of
gallbladder disease ( ie ,
cholelithiasis ,
cholecystitis , cholecystectomy ) in 210 consecutive
patients with
primary hyperlipoproteinemia showed that the prevalence of
gallbladder disease was 8 % , 18 % , and 42 % in males with
type IIa , IIb , and IV hyperlipoproteinemia , and 22 % , 48 % , and 72 % in the corresponding groups of females . -
pubmed
Translocation and
sperm abnormality assays in
mouse spermatogonia treated with
procarbazine . -
pubmed
The levels of plasma free
carnitine and
ketone bodies have been found to fluctuate inversely in fasting
individuals without
muscle disease . -
pubmed
A
patient with
lipid storage myopathy and
muscle carnitine deficiency , and his two daughters , developed exaggerated ketogenesis on fasting . -
pubmed
Three urinary excretion tests of
vitamin B12 absorption were done in 12
patients with classic
pernicious anemia . -
pubmed
Presurgical identification of hibernating myocardium by combined use of
technetium-99 m hexakis 2 - methoxyisobutylisonitrile single photon emission tomography and
fluorine-18 fluoro-2 - deoxy - D - glucose positron emission tomography in
patients with
coronary artery disease . -
pubmed
Segmental wall motion , perfusion and
18F - FDG uptake were scored in 5 segments in 14
patients with
coronary artery disease (
CAD ) , for a total number of 70 segments . -
pubmed
The survival of
hepatocellular carcinoma patients is very low , mainly due to the lack of effective treatments . -
pubmed
In addition ,
progesterone has been used to treat a few
hepatocellular carcinoma patients with promising responses . -
pubmed
Fibrodysplasia ossificans progressiva : a clue from the
fly ? -
pubmed
Economic evaluation of prophylactic treatment with
Misoprostol in
osteoarthritic patients treated with NSAIDs . -
pubmed
It is demonstrated in clinical studies that
Misoprostol is effective in preventing
gastric ulcers in
osteoarthritic patients treated with non - steroidal anti - inflammatory drugs ( NSAIDs ) . -
pubmed
From January 1987 until October 1989 , 96
patients have been treated with radical cystectomy for locally advanced
bladder cancer . -
pubmed
Cardiopulmonary receptor reflexes in normotensive
athletes with
cardiac hypertrophy . -
pubmed
The ultrastructural evidence of papillomavirusparticles within the nucleus of koilocytes are hints at a possible
human papillomavirus etiology of
vulvar carcinoma . -
pubmed
The structural brain mutant Vacuolar medulla of
Drosophila melanogaster with specific
behavioral defects and cell degeneration in the adult . -
pubmed
Cerebral and systemic metabolism of
oxygen ,
glucose ,
lactate ,
pyruvate ,
beta - hydroxybutyrate ,
acetoacetate , and
amino acids were studied in 27
comatose patients during the first 7 days after a
head injury . -
pubmed
Unlike the fasting state in normal
man , in which
beta - hydroxybutyrate and
acetoacetate are important metabolic substrates , cerebral metabolism after
head injury is almost totally dependent upon the aerobic and anaerobic metabolism of
glucose . -
pubmed
The formation of separate clusters of Mb values enabled us to distinguish
patients with different types of
MD according to the clinical diagnosis . -
pubmed
[
Canine model of
respiratory distress syndrome induced by bone marrow extraction and pathological observation of the lung tissue ] . -
pubmed
A case of
intracranial malignant teratoma found in a 27 - year - old
man was reported . -
pubmed
In addition , satisfactory retrieval of the three separate organs or of the heart and a separate bilateral
lung block was done in six
human cadavers . -
pubmed
A 59 - year - old white
woman was admitted with
reduced vision and a painless
swelling in the area of the right lacrimal gland . -
pubmed
A case is presented of severe
pancreatic injury in a 30 - year - old
man following a road traffic accident . -
pubmed
The efficacy of supplemental fresh frozen plasma ( FFP ) therapy after massive packed red cell ( PRBC ) replacement for
hemorrhagic shock was studied in 22 conditioned
dogs . -
pubmed
Consequently , routine FFP therapy for its procoagulant effects after
hemorrhagic shock should be abandoned pending controlled studies in
man . -
pubmed
Microtubule arrays in
taxol - treated
mouse dorsal root
ganglion - spinal cord cultures . -
pubmed
The diagnostic yield of EMG is emphasized in the evaluation of 122
children with
hypotonia and
weakness ( all under 3 years old ) ; abnormalities were demonstrated in 48 % leading to the diagnosis of
spinal muscular atrophy in 16 % , of
congenital myopathies in 11 % , and of
peripheral neuropathies in 8 % . -
pubmed
In 103
children with
hypotonia associated with
mental deficiency and/or
seizures , evidence of a
peripheral neuropathy was shown in 20 % . -
pubmed
4 cases of anatomically confirmed
primary hyperparathyroidism ( age of
patients 58 - 78 years ) were admitted with a serum
calcium of over 4 mmol / l in one case , over 3,5 mmol / l in a second case and over 3 mmol / l in the other two . -
pubmed
Relative immunogenicity of the cold - adapted
influenza virus A /
Ann Arbor / 6 / 60 (
A / AA / 6 / 60 - ca ) , recombinants of
A / AA / 6 / 60 - ca , and parental
strains with similar surface antigens . -
pubmed
All ca viruses were less immunogenic than their wild - type parental
strains by a factor of 10(1.3 ) to 10(3.4 ) , probably due to the restricted capacity of ca viruses to replicate in the respiratory tracts of
mice . -
pubmed
When two doses consisting of 10(5.0 ) 50 % tissue culture infective doses of A / Ann Arbor/6/60 - ca were administered at an interval of 3 weeks , solid immunity was induced against the wild - type A /
Ann Arbor / 6 / 60 parental virus , two heterologous H3N2
strains , and an
H1N1 strain . -
pubmed
Public opinion has been responsible for several state legislatures enacting bills allowing the use of laetrile for
patients with
leukemia and other
malignancies . -
pubmed
We recently cared for a 3 1/2 - year - old
child with
acute lymphoblastic leukemia , who had low initial white blood cell count , limited
organomegaly , and absence of T or B cell markers . -
pubmed
Despite favorable prognosis , the
child developed several
relapses and died with widespread infiltration of
leukemia in the central nervous system , bone marrow and viscera . -
pubmed
The effect of
schistosome infection on the presence and maturation of splenic T lymphocytes in C3H / HeN nu / nu and nu/+
mice was examined . -
pubmed
In contrast , the mean titer of sera from six nu/+
mice was log2 10.7 Nu/+
mice had typical
florid lesions , but
nu / nu mice mounted sparse granulomatous reactions around eggs in the liver without evidence for
hepatocellular damage . -
pubmed
Dispersed
liver granulomas of
nu / nu mice contained 1.2 % T and 20.3 % B lymphocytes . -
pubmed
[ An experimental study of
pyrithiamine - induced
encephalopathy in the
rat . -
pubmed
100
MS patients were followed up for an average of 5 years . -
pubmed
A
patient is described who presented with a
scleral defect which appeared dangerously close to
perforation . -
pubmed
We examined the effectiveness of 5 anticancer agents in
nude mice transplanted with 4 kinds of
uterine cervical adenocarcinoma . -
pubmed
The therapeutic effects were assessed in terms of growth inhibition rates and histological effects in the transplanted
tumors of
nude mice . -
pubmed
Toxicity of
sulphur mustard in adult
rat lung organ culture . -
pubmed
The
toxicity of the chemical warfare agent
sulphur mustard ,
( bis -( 2 - chloroethyl ) sulphide ,
HD ) , was examined in adult
rat lung organ cultures . -
pubmed
A 28 - year - old , previously healthy , normotensive
woman suddenly developed an acute
pseudobulbar palsy with
dysarthria ,
dysphagia ,
hypernasal voice and mild
right arm paresis . -
pubmed
Prognostic factors and treatment results were analysed in 28 consecutive
patients with primary
gastric lymphoma (
PGL ) diagnosed and treated , all by surgery and in many cases with additional chemotherapy ( CT ) and/or radiotherapy ( RT ) , between 1977 and 1988 . -
pubmed
According to the Kiel - classification 18
patients had a low - grade and 9 patients a
high - grade lymphoma . -
pubmed
Eighteen
patients with age - related
macular degeneration developed subfoveal membranes that were surgically removed and submitted for histopathological examination . -
pubmed
A
patient with
idiopathic hypertrophic spinal pachymeningitis (
HSP ) with predominant
involvement of the cervical and thoracic dura is reported . -
pubmed
According to a review of the English and Japanese literature on idiopathic
HSP , the prognosis of
patients with positive inflammatory signs is worse than that of those with no inflammatory signs . -
pubmed
Magnetic resonance ( MR ) imaging and localized proton MR spectroscopy of the occipital lobes were performed in a
patient with
cortical blindness following
brain trauma . -
pubmed
Six weeks after the
trauma , MR images showed
cortical lesions in both occipital lobes , while the spectra showed elevated
lactate and decreased
N - acetyl aspartate levels relative to those of healthy
volunteers . -
pubmed
[ Psychosocial outcome after individualized neuropsychological rehabilitation of
patients with
brain injuries ] . -
pubmed
[ A
depression of respiratory function following the cardiopulmonary bypass in infants and
children ] . -
pubmed
Pouchitis disease course after orthotopic liver transplantation in
patients with
primary sclerosing cholangitis and an ileal pouch - anal anastomosis . -
pubmed
METHODS : Seven
patients with an ileal pouch - anal anastomosis for
ulcerative colitis underwent liver transplantation for
primary sclerosing cholangitis . -
pubmed
RESULTS : Five of seven
patients had
pouchitis before transplant [ recurrent acute ( n = 3 ) , chronic ( n = 2 ) ] , and four of those five continued to have
pouchitis after transplant ( all chronic ) . -
pubmed
CONCLUSION :
Pouchitis occurs frequently in
patients with
primary sclerosing cholangitis and an ileal pouch - anal anastomosis for
ulcerative colitis . -
pubmed
Liver transplantation does not alter the disease course of
pouchitis for most of these
patients . -
pubmed
A total of 218 serum samples were studied : 102 samples from 72
GCT patients and 116 from
patients with
liver diseases . -
pubmed
CAI is in phase I clinical trial for
patients with advanced
cancers , yielding plasma concentrations in the in vitro anti - angiogenic range . -
pubmed
Modulatory effect of
tamoxifen and
ICI 182,780 on
adriamycin resistance in
MCF-7 human breast - cancer cells . -
pubmed
In this study the ability of the new pure anti -
estrogen ICI 182,780 to modulate the cytotoxic action of
adriamycin (
ADR ) on parental and
ADR - resistant MCF-7 ( MCF-7 ADRr )
human breast -
cancer cells was investigated and compared with that of
tamoxifen (
TAM ) . -
pubmed
In this paper , we review some of the pertinent follow - up studies of
patients with
panic disorder treated with antidepressants , high - potency
benzodiazepines , and cognitive behavior therapy , as well as data from longitudinal studies . -
pubmed
In summary , in a group of 55
patients with
Barrett ' s esophagus and
dysplasia , the authors have reported the ablation of seven
superficial cancers , the elimination of
dysplasia in 42 of the 55
patients , the complete elimination of Barrett 's mucosa in 16
patients , and the reduction of the extent of Barrett 's mucosa in all
patients who were treated with PDT and were maintained on long - term
omeprazole . -
pubmed
Repeated PDT sessions were required in some
patients to accomplish elimination of
dysplasia . -
pubmed
Esophageal strictures occurred in 53 % of
patients , but were treated satisfactorily with dilation . -
pubmed
The authors are carefully following the
patients treated with longer PDT balloons to evaluate the long - term effects on
dysplasia . -
pubmed
The authors ' results indicate that PDT alone or in combination with thermal ablation can eliminate
superficial cancers ,
dysplasia , and
Barrett ' s mucosa in many
patients with
Barrett ' s esophagus . -
pubmed
Tumor - bearing
mouse plasma evidenced high fluorescence values in the absence of
oligonucleotide administration , presumably because of elevated intrinsic plasma DNA fragments . -
pubmed
The aim of this phase II study was to examine the efficacy of combination chemotherapy comprising
epirubicin ,
cisplatin and protracted infusion
5 - fluorouracil in
patients with
metastatic prostate cancer . -
pubmed
In
patients of 70 years and under with
prostate cancer resistant to
androgen - deprivation therapy and who still have good performance status , ECF chemotherapy can achieve useful remissions . -
pubmed
All three showed excellent oral bioavailability in vivo in
nude mice and
cynomolgus monkeys and exhibited excellent antitumor efficacy against a series of
tumor cell lines when dosed orally in
nude mice . -
pubmed
Induction of
squamous cell carcinomas in the salivary glands of
rats by
potassium iodide . -
pubmed
In a 2 - year
carcinogenicity study of
potassium iodide ( KI ) in
F344 / DuCrj rats ,
squamous cell carcinomas (
SCCs ) were observed in the salivary glands of 4/40 males and 3/40 females receiving 1000 ppm KI in the drinking water . -
pubmed
Ductular proliferation with lobular
atrophy was observed at high incidence in the submandibular glands of the high - dose
animals , and
squamous metaplasia was frequently evident within the proliferative ductules and the larger interlobular ducts . -
pubmed
OBJECTIVE : The incidence and course of
neuropsychiatric symptoms were determined in pediatric
patients with
rheumatic fever . -
pubmed
RESULTS :
Obsessive - compulsive symptoms abruptly appeared and peaked during the 2 months after the onset of
rheumatic fever in 21
patients with
chorea ( 70.0 % ) and were absent in all patients without
chorea . -
pubmed
Obsessive - compulsive disorder (
OCD ) was diagnosed in five
patients with
chorea ( 16.7 % ) . -
pubmed
The nasal cavity is the major target for
tumor induction in the
rat following inhalation . -
pubmed
The present study shows that
morphine reduces the pulmonary inflammatory response to intranasal
influenza virus infection in
rats . -
pubmed
Male
Lewis rats were implanted with 75 mg
morphine pellets or placebo pellets 72 hours prior to intranasal
RAIV infection . -
pubmed
Rats were euthanized at 2 , 24 , 48 , 72 , and 96 hours after
infection . -
pubmed
Placebo - treated
rats showed a marked inflammatory response to
RAIV infection , and
morphine - treated
rats mounted less vigorous inflammatory responses to the
infection . -
pubmed
Effect of
dofetilide on survival in
patients with
supraventricular arrhythmias . -
pubmed
OBJECTIVES : This study compared survival between
patients taking
dofetilide and
patients taking placebo in a pooled analysis of randomized clinical trials of
patients with
supraventricular arrhythmias . -
pubmed
BACKGROUND : Clinical trials of antiarrhythmic drugs used to treat
supraventricular arrhythmias rarely include enough
patients to assess whether the drug being tested has an effect on survival . -
pubmed
METHODS : Data from randomized clinical trials of antiarrhythmic drug therapy of
supraventricular arrhythmias were pooled to assess the effect on survival of
dofetilide ( n = 1346 ) compared with placebo ( n = 677 ) in this
patient population . -
pubmed
CONCLUSIONS : The pooled survival analysis provided reassurance regarding the safety of
dofetilide in
patients with
supraventricular arrhythmias . -
pubmed
In 125
patients who were suspected of having
breast cancer by clinical examination , ultrasound , and X - ray mammography , additional bilateral MRM was performed . -
pubmed
The protection period from
bites by
Ae . - pubmed
The paper presents the first experience with the Russian blood substitute
Perfluorane at pulmonectomy and pleuropulmonectomy in
patients with
pulmonary tuberculosis . -
pubmed
PF used in a
patient with severe chronic
respiratory failures provided a beneficial clinical effect , improved the rheological properties and bioenergy of red blood cells ; however , the latter showed an increase in lipid peroxidation . -
pubmed
In
patients with
coronary artery disease and
intractable angina , who are not candidates for either coronary artery bypass grafting ( CABG ) or percutaneous transluminal coronary angioplasty ( PTCA ) , transmyocardial laser revascularization ( TMR ) has been developed as a new treatment . -
pubmed
In this study 32 newly diagnosed
anaplastic oligoastrocytoma patients were enrolled ( median age of 41 years , range 19 - 63 ; median Karnofsky performance status of 90 , range 70 - 100 ) . -
pubmed
This schedule of treatment provides durable response in a selected group of
anaplastic oligoastrocytoma patients . -
pubmed
Risk for
human tick - borne encephalitis ,
borrelioses , and
double infection in the pre - Ural region of Russia . -
pubmed
Lymph node
metastasis is the most frequent type of
tumor recurrence and is known to be one reason for the poor prognosis in
patients with
digestive cancer . -
pubmed
Histologically , lymphatic invasion of
cancer cells was found in primary gastric
tumors of control
mice with lymph node
metastasis . -
pubmed
However , no lymphatic invasion was observed in the gastric wall of
R-94138 - treated
mice without lymph node
metastasis . -
pubmed
[ Effects of
alfacalcidol on
osteoporosis in ovariectomized
rats ] . -
pubmed
OBJECTIVE : To investigate the effects of
alfacalcidol on
osteoporosis in
rats induced by ovariectomy ( OVX ) . -
pubmed
CONCLUSION :
Alfacalcidol effectively prevent
bone loss in OVX
rats and restore partly the trabecula , with evidenced increasing density , contents as well as maximal loads of cancellous bone , and reduce
bone resorption . -
pubmed
[ Mechanisms of the development of
venous hypertension in
patients with
varicose disease ] . -
pubmed
The examination of 539
patients with
varicose disease was fulfilled with the help of ultrasonic ( dopplerography , angioscanning ) , rentgenological ( phlebography , lymphography ) , functional ( rheovasography , photoplethysmography ) methods . -
pubmed
CONCLUSION : Milk thistle in commonly administered dosages should not interfere with
indinavir therapy in
patients infected with the human immunodeficiency virus . -
pubmed
Current guidelines for optimal blood pressure levels in obese
patients or for the treatment of
obesity -
hypertension do not provide specific recommendations that go beyond the rather general recommendation to lose weight . -
pubmed
Based on the strong ties between
obesity ,
hypertension , and
type 2 diabetes , and the similarity of complications that occur in
obesity - related
hypertension and in
hypertension associated with
type 2 diabetes , it seems appropriate to explore the optimal blood pressure levels for obese
hypertensive patients . -
pubmed
The role of antiobesity drugs in the management of the obese
hypertensive patient also remains to be defined . -
pubmed
Here , we show that
chromosomal abnormalities , including
aneuploidy and chromosome rearrangement , were significantly increased in
yeast diploid cells with defects in the origin recognition complex . -
pubmed
The bactericidal activity of
phlorotannins from
brown algae against food - borne pathogenic bacteria ( 25
strains ) ,
methicillin - resistant
Staphylococcus aureus (
MRSA ) ( nine
strains ) and
Streptococcus pyogenes ( one
strain ) was examined and compared with that of
catechins . -
pubmed
This article discusses phase I and II trials of neuronal transplantation in
humans with small
strokes in critical brain locations such as the basal ganglia region . -
pubmed
STUDY DESIGN : This is a case report of a
patient with
renal cell carcinoma and intradural
metastasis to the cauda equina . -
pubmed
METHODS : A 61 - year - old
man who underwent a nephrectomy for the treatment of
renal cell carcinoma presented with worsening
low back pain that radiated to both legs . -
pubmed
The
patient 's
low back pain and
radiating leg pain were relieved after operating . -
pubmed
Magnetic resonance imaging is a useful tool for detecting intraspinal metastasis when the
patient is complaining of a unique
pain . -
pubmed
Cost - effectiveness analysis of
tacrolimus ointment versus high - potency topical
corticosteroids in
adults with moderate to severe
atopic dermatitis . -
pubmed
OBJECTIVE : We sought to compare cost - effectiveness of high - potency topical
corticosteroids ( HPTCs ) and
tacrolimus ointment for the treatment of moderate to severe
atopic dermatitis for
patients who are not responsive to or not well controlled with mid - potency topical
corticosteroids . -
pubmed
[ Rhythmic fast activity on EEG in a
patient with
Mollaret ' s meningitis ] . -
pubmed
The patient , a 16 - year - old
boy , had episodes of acute
encephalitis followed by complete recovery every year from the age of 13 to 16 years . -
pubmed
Cell migration and programmed cell
death of
Drosophila germ cells . -
pubmed
Cell migration and programmed cell
death are essential components of
animal development and homeostasis , and the germ cells of
Drosophila provide a simple genetic system to study the molecular mechanisms that govern these important cellular processes . -
pubmed
In addition , cell migration and cell
death mechanisms are often linked , as it is important to eliminate cells that are misplaced and could present a danger to the
organism . -
pubmed
In
Drosophila , genes involved in germ cell migration can also affect programmed cell
death . -
pubmed
Here , I provide a brief review of
Drosophila germ cell migration and programmed cell
death at both the descriptive and molecular levels . -
pubmed
Response of the
Syrian hamster to two
strains of
rabies street virus by rectal instillation . -
pubmed
[ Acute
human poisoning by
trichloroethylene followed by
hepatopathy and
hyperglycemic glycosuria ] . -
pubmed
Genes on the Y chromosome influencing rate of maturation in
man : skeletal age studies in children with
Klinefelter ' s (
XXY ) and
Turner ' s ( XO ) syndromes . -
pubmed
[ CLINICAL ANALYSIS OF 98
PATIENTS WITH OBSTRUCTIVE
JAUNDICE ] . -
pubmed
Malignant hemopathies , although heterogeneous in their prognosis and
oncogenesis , represent an interesting model for studying
cancer genesis mechanisms in
man through the recurrent presence of
genetic abnormalities involved in
oncogenesis and the availability of
tumour material . -
pubmed
Normal hepatic glycogen storage after fasting and feeding in
children and
adolescents with
type 1 diabetes . -
pubmed
OBJECTIVE :
Hypoglycemia is the most important acute complication in
patients with
type 1 diabetes . -
pubmed
To test the hypothesis whether abnormal storage of glycogen in the liver is contributing to the risk of
hypoglycemia in
type 1 diabetic children and
adolescents , liver glycogen was measured . -
pubmed
STUDY DESIGN : Hepatic glycogen concentrations were measured in 19
type 1 diabetic children and
adolescents as well as in 19 age - matched controls , following overnight fasting and 4 h after two standardized meals . -
pubmed
RESULTS : Mean ( + /- SEM ) fasting hepatic
glycogen concentrations measured in arbitrary units ( au ) were similar in
type 1 diabetic subjects and controls ( 4.98 + /- 0.36 vs. 4.48 + /- 0.33 au ; p = 0.31 ) . -
pubmed
Hepatic glycogen accumulation after feeding was 19.1 % in
diabetic children and
adolescents compared with 35.8 % in controls , but this difference did not reach significance . -
pubmed
CONCLUSION : In
children and
adolescents with moderately controlled
type 1 diabetes , hepatic glycogen stores after fasting and feeding are comparable to those of matched controls . -
pubmed
Thirty
women ( 13.4 % ) were diagnosed with a
recurrence . -
pubmed
General
gonococcal peritonitis in young
girls under puberty ; report of two cases , one simulating
appendicitis , operated . -
pubmed
It is well documented that the range of the daily fluctuations in IOP is greater in
patients with
glaucoma than in normal individuals , and a report by Asrani et al . -
pubmed
There have been reports of nocturnal increases in IOP , particularly in
patients with normal tension
glaucoma , and some ophthalmologists believe these may account for progression of
visual field loss in some
patients with
glaucoma . -
pubmed
Several recent studies of diurnal IOP in
patients with
glaucoma have failed to document such diurnal IOP spikes , so the published data available have not supported this hypothesis . -
pubmed
SUMMARY : One recent report has reconfirmed that a single IOP measurement in the office may not accurately indicate what is happening to the IOP of a
patient with
glaucoma throughout the day . -
pubmed
Our current knowledge of the molecular pathogenesis of the diffuse adult
astrocytic tumours is vast if compared to 20 years ago , yet we are far from understanding the details of this process at the molecular level and using such an understanding to logically and specifically treat
patients '
tumours . -
pubmed
Lipin is one such protein identified in a
lipodystrophic mouse strain and found to be critical for normal adipocyte differentiation . -
pubmed
Our aim was to compare these two types of rotationplasty and determine whether the knee should be preserved in
children with
tumours of the proximal femur . -
pubmed
Postimplant chest x - rays were obtained at a median of 912 days ( range 147 to 3023 ) , and 4
patients ( 1.7 % ) experienced at least one seed
embolus to the lung . -
pubmed
All 4
patients had received an I-125 implant , resulting in a
pulmonary embolus rate for I-125 of 2.7 % ( 4 of 146 ) and for
palladium-103 of 0 % ( 0 of 92 ) . -
pubmed
CONCLUSIONS : Seed
embolism to the lungs is a rare event when
patients undergo implantation using the real - time method . -
pubmed
A
canine model of normovolaemic acute
anaemia . -
pubmed
The objective was to develop a non - terminal , acute normovolaemic
anaemia model in
dogs that has minimal effects on
patient well - being . -
pubmed
The model was primarily developed to determine echocardiographic values as well as Doppler abdominal splanchnic blood flow parameters in
anaemic dogs as part of a study that will compare these results to similar studies in
babesiosis - induced
anaemia . -
pubmed
The model may also be useful in the evaluation of the pathophysiology of
anaemia in
dogs or as a model for
anaemia in
humans . -
pubmed
A spontaneous ,
multisystem autoimmune disease developed in aging ( & gt;20 weeks ) transgenic
mice ( n = 25 ) , with a 32 % incidence of
arthritis , and by 45 weeks , all
mice had developed
glomerulonephritis and
pneumonitis , and most had antihistone antibodies . -
pubmed
METHODS : Sixty sedentary
women with
FM , ages 18 - 60 years , were randomly assigned to either deep water running ( DWR ) or land - based exercises ( LBE ) . -
pubmed
Visual analog scale of
pain ,
Fibromyalgia Impact Questionnaire ( FIQ ) , Beck Depression Inventory , Short Form 36 Health Survey ( SF-36 ) , and a
patient 's global assessment of response to therapy ( PGART ) were measured at baseline , week 8 , and week 15 . -
pubmed
Therefore , DWR could be studied as an exercise option for
patients with
FM who have problems adapting to LBE or lower limbs limitations . -
pubmed
In the presence of
EDTA , the activity of
coumermycin A(1 ) was significantly enhanced ( 8- to 40 - fold ) against all four organisms in the synthetic medium lacking
Mg ( 2 + ) ;
novobiocin activity was increased to a lesser extent ( 4- to 16 - fold ) against three
strains and remained unchanged against
P. - pubmed
Rates of
IPD in the Indigenous and non - Indigenous under 2 - year - old population were similar in 2004 ( 91.5 and 93.6 cases per 100,000 population , respectively ) following a targeted introduction of the 7 - valent
pneumococcal conjugate vaccine ( 7vPCV ) in mid-2001 for Indigenous infants and children . -
pubmed
The work presented here suggests that , further to its genotoxic properties , at levels close to
human exposure
PhIP stimulates cellular signalling pathways that are linked to the promotion and progression of
neoplastic disease . -
pubmed
The
patients underwent the corrective refractive procedure by means of LASIK to correct the
myopia . -
pubmed
We describe a 45 - year - old
woman presenting with unilateral
proptosis and
periorbital xanthelasma . -
pubmed
Effect of treatment of
hyperuricemia with
allopurinol on blood pressure ,
creatinine clearence , and
proteinuria in
patients with normal renal functions . -
pubmed
However , there is no data about the effect of lowering
uric acid level on
hypertension , renal function , and
proteinuria in
patients with
glomerular filtration rate (
GFR ) & gt;60 ml / min . -
pubmed
We therefore conducted a prospective study to investigate the benefits of
allopurinol treatment in
hyperuricemic patients with normal renal function . -
pubmed
MATERIALS AND METHODS : Forty - eight
hyperuricemic and 21 normouricemic
patients were included in the study . -
pubmed
Hyperuricemic patients received 300 mg / day
allopurinol for three months . -
pubmed
Hence , management of
hyperuricemia may prevent the progression of
renal disease , even in
patients with normal renal function , suggesting that early treatment with
allopurinol should be an important part of the management of
chronic kidney disease (
CKD )
patients . -
pubmed
A 55 - year - old
man was referred to our hospital for progressive
dyspnea . -
pubmed
The
patient died of
respiratory failure a month later and an autopsy revealed no significant inflammatory changes in either lung . -
pubmed
Antimicrobial effects of photodynamic therapy on
patients with
necrotic pulps and
periapical lesion . -
pubmed
As a result
human somatic cells undergo replicative senescence , which plays an important role in suppressing
tumorigenesis , and at the same time contributes to the process of aging . -
pubmed
RESULTS : Bone marrow
oedema around the growth plate and
joint effusion occurred in all
patients . -
pubmed
Synovitis occurred in 13/15
patients . -
pubmed
6
patients had a fall before presenting with
SCFE . -
pubmed
9
patients had no fall prior to presentation , physis and periost were intact in 7/9 ; periarticular
oedema was not seen . -
pubmed
A fulcrum - like alignment ,
impingement of the epiphysis on the metaphysis with a small area of physical contact , was seen in 8
patients , 6/8 had a prior fall . -
pubmed
PURPOSE OF REVIEW : To review the state - of - the - art and new developments in the management of
patients with
brain metastases . -
pubmed
Here , we present in vitro and in vivo preclinical evidence in support of chemosensitization of
pancreatic cancer cells by
3,3 - diindolylmethane (
DIM ) , a natural compound that can be easily obtained by consuming
cruciferous vegetables . -
pubmed
The ligand ,
HQO , and its complexes were tested against one
strain Gram + ve bacteria (
Staphylococcus aureus ) ,
Gram - ve bacteria (
Escherichia coli ) . -
pubmed
OBJECTIVES : We analyzed data from patients with
ASC - US
LBC and positive
HPV test results . -
pubmed
The rates of
infection by Plasmodium species in mosquitoes were 0.37 % ( 22/5,886 ) for
Plasmodium vivax(Grassi & amp ; Feletti ) and 0.10 % ( 6/5,886 ) for
Plasmodium falciparum ( Welch ) . -
pubmed
darlingi was 2.21 infective
bites / person / year , 1.25 for
An . - pubmed
To determine whether this proteolytic cascade is altered during the progression of
AD , we examined
human frontal and parietal cortex tissues from aged
subjects with a clinical diagnosis of
AD , mild
cognitive impairment , or no
cognitive impairment . -
pubmed
HHV-6 has been associated with
encephalitis in children recently . -
pubmed
This study aimed to establish a real time PCR assay for simultaneous detection of the two subtypes of
HHV-6 , and apply this new assay to children with suspected
encephalitis , then analyze the relationship between the
infection with
HHV-6 and
encephalitis in children . -
pubmed
There were no cross - reaction with
herpes simplex virus type 1 , type 2 ( HSV-1 ,
HSV-2 ) ,
varicella - zoster virus (
VZV ) ,
cytomegalovirus (
CMV ) ,
Epstein - Barr virus (
EBV ) ,
hepatitis B virus ,
Staphylococcus aureus ,
Mycoplasma pneumoniae and
human DNA . -
pubmed
HHV-6 positive rate by the real time PCR assay was 4.72 % ( 21/445 ) , including 4 cases with
HHV-6A infection , 16 cases of
HHV-6B infection and 1 case with mixed
HHV-6A and
HHV-6B infection . -
pubmed
It will provide an early and sensitive diagnosis of
HHV-6 encephalitis in
children . -
pubmed
Functional memory B cells and long - lived plasma cells are generated after a single
Plasmodium chabaudi infection in
mice . -
pubmed
Antibodies have long been shown to play a critical role in naturally acquired immunity to
malaria , but it has been suggested that Plasmodium - specific antibodies in
humans may not be long lived . -
pubmed
The cellular mechanisms underlying B cell and antibody responses are difficult to study in
human infections ; therefore , we have investigated the kinetics , duration and characteristics of the Plasmodium - specific memory B cell response in an
infection of
P. - pubmed
Thus , in this model of
malaria , both functional
Plasmodium - specific memory B cells and long - lived plasma cells can be generated , suggesting that defects in generating these cell populations may not be the reason for generating short - lived antibody responses . -
pubmed
Ethanol produced
fatty liver and oxidant stress in WT
mice but
liver injury ( transaminases , histopathology ) was minimal . -
pubmed
Ethanol - induced
steatosis and oxidant stress were blunted in the KO
mice ( no
liver injury ) but restored in the KI
mice . -
pubmed
Transcription of cytokine genes was evaluated in the lung and spleen of
chickens vaccinated with various serotype 1
Marek ' s disease (
MD ) vaccines . -
pubmed
Angioplasmocellular hyperplasia : a clinicopathologic study of 10
patients . -
pubmed
METHODS : The records of 10
patients ( mean age , 45 years ; range , 17 to 71 years ) with characteristic histologic features of
angioplasmocellular hyperplasia were reviewed and the histopathologic findings , clinical features , and medical histories analyzed . -
pubmed
Subjective and objective criteria of
xerophthalmia and
xerostomia were investigated in 120
HCV Egyptian
patients . -
pubmed
Sixty six of 120
patients ( 55 % ) had
SC ; all ( 100 % ) were proved to have
xerostomia by sialoscintigraphy and
xerophthalmia detected by ophthalmologic tests . -
pubmed
Using dacroscintigraphy all SC
patients ( 100 % ) were positive for
lacrimal drainage abnormalities . -
pubmed
High prevalence of
SC in
HCV Egyptian
patients was detected . -
pubmed
The genetic diversity of 35
Bacillus sphaericus strains was analyzed by a newly developed multilocus sequence typing ( MLST ) scheme , toxin gene pool survey , and mosquito bioassay . -
pubmed
The recently discovered
porcine boca - like virus (
Pbo - likeV ) is a member of the Parvoviridae family , genus Bocavirus , and it is potentially associated with
swine disease . -
pubmed
Several studies have associated Pbo - likeV with postweaning
multisystemic wasting syndrome in
pigs , but the full spectrum of clinical disease and the epidemiology of
Pbo - likeV infection remain unclear . -
pubmed
Higher
infection rates were found in diseased
pigs ( 56.1 % , 101/180 ) compared with healthy
pigs ( 16.7 % , 13/78 ) ( P & lt ; 0.05 ) . -
pubmed
OBJECTIVE : To study the effect and mechanism of
Soybean Isoflavones (
SIF ) on the cognitive performance of female
mice after
sleep deprivation for 72h . -
pubmed
METHODS : A total of 459
patients who underwent curative resection of
NSCLC were studied ( median follow - up duration , 4.01 years ) . -
pubmed
Different pattern of carotid and myocardial changes according to left ventricular geometry in
hypertensive patients . -
pubmed
A total of 476
hypertensive patients were prospectively recruited . -
pubmed
Carotid arterial function and IMT showed worse values in concentric geometry , whereas LV systolic and diastolic function were worse in hypertrophic geometry , suggesting a discrepancy between carotid arterial and LV function in
hypertensive patients . -
pubmed
UNLABELLED : A superparamagnetic
gammaFe ( 2 ) O ( 3 ) nanocarrier was developed , characterized by spectroscopic methods and evaluated for the delivery of a decoy
oligonucleotide ( dODN ) in
human colon
carcinoma SW 480 cells . -
pubmed
Clinical implications of variations in anti -
infliximab antibody levels in
patients with
inflammatory bowel disease . -
pubmed
Pharmacological management of
type 2 diabetes mellitus in
patients with
CKD . -
pubmed
Effective and appropriate control of blood
glucose can significantly reduce the risk of
diabetic complications and all - cause mortality in
patients with
diabetes mellitus and recent years have seen a number of new anti - diabetic medications marketed . -
pubmed
However , approximately 30 % of
patients with
diabetes mellitus develop progressive
chronic kidney disease (
CKD ) limiting the selection of agents that can safely be used . -
pubmed
Whilst older agents such as
metformin and the
sulphonylureas remain the mainstay of initial treatment , the elimination and adverse effects profile of a number of these drugs can be a concern in
patients with
CKD . -
pubmed
Treatment guidelines for anti - diabetic therapy rarely consider safe and efficacious management of those
patients with
CKD . -
pubmed
The purposes of the studies were to investigate the cause of low exposure , develop , and test an alternative formulation with improved exposure , and establish the dose to be tested in future studies in
cancer patients . -
pubmed
CONCLUSION :
Amuvatinib LSC , 300 mg every 8 h , is being studied in
cancer patients based on the improved exposure and similar safety profile to
amuvatinib DPC . -
pubmed
The importance of imaging procedures in evaluating
painful neck masses : two
patients with a
painful internal jugular vein thrombosis . -
pubmed
METHODOLOGY : We reviewed our hospital charts from Jan 2007 to December 2010 and made a comparative study about early and delayed LC for mild to moderate
gallstone pancreatitis in 80
patients . -
pubmed
In this study , we reviewed 125
patients with
AVMs , demonstrating overall sensitivities of 90 % for CTA , 89 % for T2 - weighted MRI , and 74 % for MRA . -
pubmed
The aim of this open - label pilot trial was to evaluate the safety and efficacy of long - term LES stimulation using a permanently implanted LES stimulator in
patients with
gastroesophageal reflux disease (
GERD ) . -
pubmed
The number and timing of sessions was tailored to each
patient 's
GERD profile . -
pubmed
Patients were evaluated using
GERD - HRQL , daily symptom and medication diaries , SF-12 , esophageal pH , and high - resolution manometry . -
pubmed
At their 6 - month follow - up , 91 % ( 21/23 ) of the
patients were off PPI and had significantly better median
GERD - HRQL on LES stimulation compared to their on - PPI
GERD - HRQL at baseline ( 9.0 vs. 2.0 ; p & lt ; 0.001 ) . -
pubmed
Immunotherapies are therefore ideal adjuncts to standard
tumor therapies since they aim to activate the
patient 's immune system against malignant cells even outside the primary treatment areas ( abscopal effects ) . -
pubmed
Self - expanding metal stents for preoperative biliary drainage in
patients receiving neoadjuvant therapy for
pancreatic cancer . -
pubmed
METHODS :
Fructose and lactose intolerance ( defined by positive symptom index ) and
malabsorption ( defined by increased
hydrogen /
methane ) were determined in 1372
FGID patients in a single centre using breath testing . -
pubmed
BACKGROUND : Prognostic implications of echocardiographic assessment of
pulmonary hypertension (
PH ) in non - selected
patients hospitalized for
acute heart failure (
AHF ) are not clearly defined . -
pubmed
METHODS : We prospectively included 1210 consecutive
patients admitted for
AHF . -
pubmed
Patients with significant
heart valve disease were excluded . -
pubmed
One - year mortality was lower for
patients with normal PASP ( 1.32 per 10 person - years ) , intermediate for patients with non - measurable , mild and moderate
PH ( 2.48 , 2.46 and 2.62 per 10 persons - year , respectively ) and higher for those with severe
PH ( 4.89 per 10 person - years ) . -
pubmed
METHODS :
ICH patients in a defined Swedish population ( 1.14 million inhabitants ) were prospectively registered during 1996 . -
pubmed
Patients surviving 1 year after
ICH onset were followed - up regarding survival status and cause of
death until December 2009 using data from the National Census Office and the National Cause of Death Register . -
pubmed
RESULTS : Of 323
patients with
ICH , 172 ( 53 % ) survived after 1 year , 127 ( 39 % ) after 5 years and 57 ( 18 % ) after 13 years . -
pubmed
Prognostic impact of cigarette smoking on the survival of
patients with established
nasopharyngeal carcinoma . -
pubmed
BACKGROUND : Cigarette smoking is associated with the etiology of
nasopharyngeal carcinoma ; however , the influence of smoking on survival in
patients with established
nasopharyngeal carcinoma remains unknown . -
pubmed
METHODS : We retrospectively analyzed 1,849
patients with
nasopharyngeal carcinoma who were categorized as never , former , and current smokers . -
pubmed
CONCLUSIONS : Pretreatment cigarette smoking is an independent , poor prognostic factor for
patients with
nasopharyngeal carcinoma , which is associated with increased risk of
death , progression , locoregional
relapse , and distant
metastasis , with the risk increasing with pack - years . -
pubmed
IMPACT : It is clear that cigarette smoking not only promotes carcinogenesis in the
normal nasopharyngeal epithelium , but also affects the survival of
patients with
nasopharyngeal carcinoma . -
pubmed
Effects of early and late treatment with
L - baclofen on the development and maintenance of
tinnitus caused by
acoustic trauma in
rats . -
pubmed
for 4.5 weeks starting at 17.5 weeks following noise exposure ) with
l - baclofen on the psychophysical attributes of
tinnitus in a conditioned lick suppression model following
acoustic trauma in
rats . -
pubmed
METHODS : This study examined the CSF from 103
patients : bilateral
MMD , n=58 ( 56.3 % ) ; unilateral
MMD , n=19 ( 18.4 % ) ;
atherosclerotic cerebrovascular disease (
ACVD ) , n=21 ( 20.4 % ) ; and control group , n=5 ( 4.9 % ) . -
pubmed
The
patients rated the ultrasound and fluoroscopic experiences on a scale from 1 to 10 for convenience and
pain ; in addition , they indicated their preference between the 2 techniques . -
pubmed
The effects of oral
L - carnitine treatment on blood lipid metabolism and the body fat content in the
diabetic patient . -
pubmed
A random double blind study was designed to investigate the effects of
L - carnitine treatment ( 12 weeks , 3 g / d ) on lipid metabolism and the fat content of the body in the
patients with
non - insulin - dependent diabetes mellitus . -
pubmed
PATIENTS : From January 2006 to June 2012 , 27
tumors in 17
patients with
liver metastases from
colorectal cancer were treated using RFA after systemic chemotherapy . -
pubmed
One
patient had a complication(
liver abscess).Of the 27
tumors , 9 were larger than 20 mm in diameter , and 4 of these 9
tumors showed local
recurrence after RFA . -
pubmed
Male
C57BL / 6 mice were fed for 12 weeks with a high - fat diet to induce
obesity . -
pubmed
USM relaxations induced by
NO ( acidified
sodium nitrite ) ,
NO donors (
S - nitrosoglutathione and
glyceryl trinitrate ) , and
BAY 41 - 2272 [
5 - cyclopropyl-2 -[ 1 -( 2 - fluoro - benzyl )- 1H - pyrazolo [ 3,4 - b ] pyridin-3 - yl ]- pyrimidin-4 - ylamine ] ( sGC stimulator ) were markedly reduced in
obese compared with lean
mice . -
pubmed
In contrast , USM relaxations induced by
BAY 60 - 2770 ( sGC activator ) were 43 % greater in
obese mice ( P & lt ; 0.05 ) , which was accompanied by increases in
cGMP levels . -
pubmed
Long - term oral
BAY 60 - 2770 administration fully prevented the impairment of USM relaxations in
obese mice . -
pubmed
In conclusion , impaired USM relaxation in
obese mice is associated with ROS generation and down - regulation of sGC -
cGMP signaling . -
pubmed
Prevention of sGC degradation by
BAY 60 - 2770 ameliorates the
impairment of urethral relaxations in
obese mice . -
pubmed
Hepatic colorectal
metastases involving infra - hepatic inferior vena cava in high risk
patients for extended resection : an alternative method for achieving radical resection in
patient with borderline liver remnant . -
pubmed
We believe that aggressive treatment of liver colorectal
metastases should be given to all suitable
patients . -
pubmed
Routine ante - mortem testing of
cattle herds is required for disease surveillance and control , due to the asymptomatic nature of the
infection . -
pubmed
METHODS :
Patients with moderately severe
UC , in remission , were randomized to MBSR or time / attention control . -
pubmed
In a second experiment ,
macaques were given
GSK744 LA 1 week before virus administration and challenged repeatedly until
infection occurred . -
pubmed
CONCLUSION : In clinical practice ,
platinum /
fluoropyrimidines with adequate treatment duration is recommended for
stage II / III gastric cancer patients according to the 7(th ) edition of the AJCC staging system after curative gastrectomy even with limited lymphadenectomy . -
pubmed
METHODS : We tested two groups of women , screened using the
Autism Spectrum Quotient - Group 1 : n = 415
women with
ASC ( mean age 36.39 + - 11.98 years ) ; and Group 2 : n = 415 controls ( mean age 39.96 + - 11.92 years ) . -
pubmed
We proposed to evaluate the association between serum indirect
bilirubin levels and
liver fibrosis in
patients with
chronic hepatitis C (
CHC ) genotype 1b . -
pubmed
Biopsy proven
CHC genotype 1b
patients ' demographics , clinical and histopathological characteristics were evaluated . -
pubmed
Logistic regression analysis was done to evaluate the clinical , laboratory and demographic features of the histologically proven
liver fibrosis in
CHC patients . -
pubmed
A total of 112 biopsy proven
CHC genotype 1b
patients were enrolled into the study . -
pubmed
Liver fibrosis scores were measured by using Ishak
fibrosis scores and were divided into two groups ;
fibrosis scores & lt;= 2 were categorized as mild
fibrosis , 82
patients ( 73.2 % ) , whereas
fibrosis scores & gt;2 were categorized as advanced
fibrosis group , 30
patients ( 26.8 % ) . -
pubmed
Patients with advanced
fibrosis had lower indirect
bilirubin levels than the mild
fibrosis group ( 0.28 + - 0.02 mg / dl vs. 0.44 + - 0.032 mg / dl , p<0.001 , respectively ) . -
pubmed
METHODS : Immunohistochemical analysis was carried out retrospectively on
tumor samples from
patients treated for
bladder cancer . -
pubmed
In the 1st study , 1,207 youth ( 685
girls ) ages 7 to 18 completed the R - SCS - C as well as measures of imaginary audience ,
anxiety ,
depression , and positive and negative affect . -
pubmed
Long - term comparison of GOS - E scores in
patients treated with
phenytoin or
levetiracetam for posttraumatic
seizure prophylaxis after
traumatic brain injury . -
pubmed
Patients were identified by cross - referencing a list of patients receiving
LEV or PHT , with a list of
patients with ICD-9 code consistent with
TBI . -
pubmed
CONCLUSIONS : Long - term functional outcome in
patients who experienced a
TBI was not affected by treatment with
PHT or
LEV ; however ,
patients treated with
PHT had a higher incidence of
fever during hospitalization . -
pubmed
Complement alternative pathway activation in
human nonalcoholic steatohepatitis . -
pubmed
Recently we reported complement activation in
human NASH . -
pubmed
Here , alternative pathway components were investigated in liver biopsies of obese
subjects with healthy livers ( n = 10 ) or with
NASH ( n = 12 ) using quantitative PCR , Western blotting , and immunofluorescence staining . -
pubmed
Comparisons were made between
tinnitus and non -
tinnitus side of
patients and normal ears of controls . -
pubmed
Aryl organophosphate flame retardants induced
cardiotoxicity during
zebrafish embryogenesis : by disturbing expression of the transcriptional regulators . -
pubmed
Because a previous study reported that two
aryl - OPFRs induced
cardiotoxicity during
zebrafish embryogenesis , we designed experiments to compare the heart developmental
toxicity of a series of
aryl - OPFRs with
alkyl - OPFRs and explored possible internal mechanism . -
pubmed
First , acute
toxicity of 9 frequently used OPFRs were studied with
zebrafish embryos ( 2 - 96 hpf ) . -
pubmed
In clinical islet transplantation , allogeneic islets of Langerhans are transplanted into the portal vein of
patients with
type 1 diabetes , enabling the restoration of normoglycemia . -
pubmed
Composition of
human faecal microbiota in resistance to
Campylobacter infection . -
pubmed
In mice , specific species composition of gut microbiota enhances susceptibility to
Campylobacter jejuni but little is known about the specific composition of the
human gut microbiota in providing protection from
infections caused by enteropathogens . -
pubmed
Species composition of
human gut microbiota is important for colonization resistance to
Campylobacter infection . -
pubmed
Increased Nonalternans Repolarization Variability Precedes
Ventricular Tachycardia Onset in
Patients with Implantable Defibrillators . -
pubmed
This study was conducted to determine if NARV increases prior to
VT in
patients with implantable cardioverter defibrillators ( ICDs ) . -
pubmed
METHODS : TWA and NARV were calculated from
shock - channel electrograms preceding onset of
VT or non - VT events in
patients with an ICD . -
pubmed
In each
patient , presence of both a
VT and a non - VT event with the same QRS morphology before the event was required . -
pubmed
RESULTS : Before the disease episode , hair T3 levels differed significantly between F -
MDD patients and HC . -
pubmed
In the disease episode , hair T3 levels differed significantly between F - MDD or R -
MDD patients and HC ; and hair T4 levels differed significantly between R -
MDD patients and HC . -
pubmed
Hair T3 levels significantly negative correlated with HAMD scores in F -
MDD patients . -
pubmed
METHODS :
Patients with
PsA were monitored in a prospective , observational study . -
pubmed
We investigated the effect of an acute experimental stress ( impending Trier Social Stress Task in the morning ) on pre - sleep measures of
cortisol and autonomic arousal in perimenopausal
women with and without
insomnia that developed in the context of the menopausal transition . -
pubmed
Following adaptation to the laboratory , twenty two
women with ( age : 50.4 + - 3.2 years ) and eighteen
women without ( age : 48.5 + - 2.3 years )
insomnia had two randomized in - lab overnight recordings : baseline and stress nights . -
pubmed
These results show that pre - sleep stress impacts autonomic nervous system functioning before and during sleep in perimenopausal
women with and without
insomnia . -
pubmed
The aim of this study was to investigate the effect of
carnosine (
CAR ) alone and together with
vitamin E (
Vit E ) on
alcoholic steatohepatitis (
ASH ) in
rats . -
pubmed
During structured interviews , we examined the co - occurrence of
headaches and
epilepsy in children and their families : ( 1 ) 172
children from the
headache clinic , were questioned for the number and type of
epileptic seizures and
epilepsy diagnosis . -
pubmed
( 2 ) Around 70
children from the
epilepsy clinic for the frequency and type of
headaches and
headache syndrome diagnosis . -
pubmed
( 3 ) A total of 149 parents of
children with benign childhood
epilepsy with
centro - temporal spikes (
BCECTS ) and childhood
absence epilepsy (
CAE ) , for the relative frequency of
headaches in first- and second - degree relatives . -
pubmed
RESULTS : Out of 172 , 84 ( 48.8 % )
children with
headache had a
migraine and 60 ( 34.9 % ) had
tension headaches ; 3
children ( 1.7 % ) had
epilepsy or unprovoked
seizures . -
pubmed
Eight out of 70
patients with
epilepsy had
headaches ( 11.4 % ) ; none had
migraine . -
pubmed
Around 43 % of
patients with
BCECTS or
CAE had a family history of
headache , more prevalent in first - degree relatives of
children with
BCECTS than
CAE . -
pubmed
Family history of
headache was frequent in
patients with
BCECTS and
CAE , without any significant difference between the two . -
pubmed
The larval stages of the cestodes
Echinococcus multilocularis and
Echinococcus granulosus cause the important
zoonoses known as larval
echinococcoses . -
pubmed
This was a case - control study included 60 (
AIS ) cases , and 100 healthy
children with comparable age and gender as control group . -
pubmed
Twelve hours after last injection ,
rats were killed by
decapitation and brain areas were rapidly isolated . -
pubmed
Autologous hematopoietic cell transplantation ( AHCT ) is standard therapy for eligible
patients with
multiple myeloma . -
pubmed
Mycobacterium tuberculosis causes
tuberculosis (
TB ) , a disease that killed more than 1.5 million people worldwide in 2014 , and the
Bacillus Calmette Guerin ( BCG ) vaccine is the only currently available vaccine against
TB . -
pubmed
CONCLUSIONS : Phalangeal QUS appeared a useful tool to evaluate bone quality in
BC women on AIs . -
pubmed
METHODS : Between 2007 and 2014 , 14
patients ( mean age 39 years ) with suspected
penile fracture underwent US examinations . -
pubmed
RESULTS : The most common
blunt injury to the penis that occurred in nine
patients was
penile fracture due to
rupture of the corpus cavernosum . -
pubmed
Four
patients presented an
injury to the subtunical venous plexus in the absence of complete tunical disruption . -
pubmed
One
patient had
urethral rupture with
inability to urinate and apparent
urethrorrhagia . -
pubmed
PURPOSE : Development of
metastasis in
patients with
breast cancer (
BC ) is the most important negative prognostic factor and this process mainly begins with lymphatic involvement . -
pubmed
The purpose of this study was to investigate if laterality is an independent prognostic factor for
metastasis in N3
breast cancer patients . -
pubmed
Patients with left
BC had significantly higher rate of axial bone
metastases compared with the right BC group ( 55.7 vs 35.8 % , p<0.02 , respectively ) . -
pubmed
Median OS did not differ between the groups , however , there was a trend towards lower OS in
patients with left
BC ( p=0.68 ) . -
pubmed
A 66 - year - old
man who presented with
coma was found to have isolated severe
hyperammonemia and diagnosed with a late - onset
urea - cycle disorder . -
pubmed
However , these results support the concept of directly modifying peripheral blood as a novel approach to conveniently treat
articular cartilage lesions in
patients . -
pubmed
One - hundred and thirty - six ( 40 % ) , 122 ( 35 % ) , and 85 ( 25 % )
patients had normal coronary arteries , single - vessel
CAD , and multivessel
CAD , respectively . -
pubmed
Development of a qualitative assay for screening of
Bordetella pertussis isolates for
pertussis toxin production . -
pubmed
We analyzed 30 samples of middle - ear mucosa in
patients affected by
chronic suppurative otitis media with ear drum perforation with / without
cholesteatoma and
otosclerosis as control . -
pubmed
This new combination therapy may lead to more effective disease eradication , especially in
patients at high risk of TKI resistance and
disease progression . -
pubmed
This study demonstrates that a
KD extends longevity and healthspan in
mice . -
pubmed
BACKGROUND : The prevalence and significance of
right ventricular dysfunction (
RVD ) in
patients with
cardiogenic shock due to
acute myocardial infarction (
AMI -
CS ) have not been well characterized . -
pubmed
In the
SHOCK trial and registry , respectively , 38 % and 37 % of
patients had
RVD , but
RVD was not associated with 30 - day or 6 - month survival ( hazard ratio [ HR ] 1.51 , ( 99 % CI 0.92 - 2.49 ; P = .10 ) . -
pubmed
Routine assessment with pulmonary artery catherization allows detection of
RVD ; however , further work is needed to identify interventions that will result in improved outcomes for these
patients . -
pubmed
Based on this novel strategy , we successfully detected miR-141 , a promising biomarker for
human prostate cancer , with high selectivity . -
pubmed
STUDY DESIGN : A retrospective analysis of a prospectively collected data of adult
spinal deformity patients was carried out . -
pubmed
Compliance with an Enhanced Recovery After a Surgery Program for
Patients Undergoing Gastrectomy for Gastric
Carcinoma : A Phase 2 Study . -
pubmed
METHODS : This phase 2 study enrolled 168
patients undergoing elective gastrectomy for
gastric carcinoma . -
pubmed
Therefore , the aim of this study is to investigate the effect of solution volume on the detection rate of a salivagram in
patients with
brain lesion , and to determine the optimal solution volume of salivagram . -
pubmed
We retrospectively reviewed clinical data and solution volume of radionuclide used in the salivagram of 77
patients with
dysphagia , and the
patients were divided into 2 groups according to the solution volume of the radionuclide ( Group A-0.1 mL vs Group B-0.5 mL ) . -
pubmed
Even a small difference of the solution volume of radionuclide in salivagram can affect the detection rate of salivary aspiration in
patients with
brain lesion . -
pubmed
Both of them were comparable to the first - line anti - TB agents
INH and
RIF against
MTB H37Rv , and were far more potent than
INH and
RIF against
MDR - TB 16833 and 16995
strains . -
pubmed
Alzheimer ' s disease (
AD ) is a well - known
neurodegenerative disorder affecting millions of old
people worldwide and the corresponding epidemiological data highlights the significance of the disease . -
pubmed
HIV-1 transmission is usually initiated by a single viral
strain called transmitted/ founder ( T / F ) virus . -
pubmed
In in vitro models ,
HIV-1 can efficiently spread via cell - free and virological synapse ( VS)-mediated cell - to - cell
infection . -
pubmed
These compounds isolated from
Tetradium plants exhibit a wide range of biological activities in vitro and in vivo including antitumor , antibacterial , anti - inflammatory , insecticide , cardioprotective and lipid - lowering , treating
CNS disorders , digestive system regulation and endocrine system improving activities . -
pubmed
Emergence of
methicilin resistant
Staphylococcus aureus (
MRSA )
strains is a major cause of infirmity worldwide and has limited our therapeutic options against these pathogens . -
pubmed
After 24 h ,
Methicillin - resistant
Sthaphylococcus aureus (
MRSA )
strains showed
fluoxetine MICs equal to 64 mug / mL and 128 mug / mL , respectively . -
pubmed
Anti - oxidant and anti - inflamatuar effectiveness of
caftaric acid on
gastric ulcer induced by
indomethacin in
rats . -
pubmed
As a result of our study ,
caftaric acid showed anti - oxidant and anti - inflammatory effects in
indomethacin - induced
gastric ulcer in
rats . -
pubmed
PATIENTS AND METHODS : In all , 21
patients with localized
prostate cancer were treated with a RR for 3DCRT in 40 x 2 Gy . -
pubmed
The
patient tolerance and acute rectal
toxicity were surveyed during radiotherapy using Common Terminology Criteria for Adverse Events ( CTCAE ) v.4.0 . -
pubmed
RESULTS :
Patients tolerated the RR well during 20 fractions with mild degree of
anal irritation . -
pubmed
Finally ,
AdoCbl alleviates deficits in
dopamine release sustainability caused by
LRRK2 disease variants in
mouse models . -
pubmed
This is a case report of sinonasal and orbital
Ewing ' s sarcoma in a 24 - year - old male
patient who presented with a history of
right nasal obstruction ,
right eye pain and
periorbital edema . -
pubmed
Potentially pathogenic
strains of non-01
V. - pubmed
Monitoring of Neutrophil Recruitment to
Mice Lungs During Pneumonic
Plague . -
pubmed
with the
plague bacterium
Yersinia pestis to study in vivo neutrophil responses to the
infection . -
pubmed
Patients with advanced EBDC often experience
biliary obstruction , which can lead to
jaundice and progress to
death . -
pubmed
Observations : A 35 - year - old
woman presented during the third trimester of pregnancy with bilateral uncontrolled
primary open angle glaucoma . -
pubmed
marinoi , demonstrating that several
strains (
Arenibacter algicola strain SMS7 ,
Marinobacter salarius strain SMR5 ,
Sphingorhabdus flavimaris strain SMR4y ,
Sulfitobacter pseudonitzschiae strain SMR1 ,
Yoonia vestfoldensis strain SMR4r and
Roseovarius mucosus strain SMR3 ) stimulate growth of the diatom partner . -
pubmed
OBJECTIVES : This study sought to evaluate the association between contrast - enhanced multidetector computed tomography ( CE - MDCT ) attenuation and local epicardial conduction speed ( ECS ) and electrographic abnormalities in
patients with
arrhythmogenic right ventricular cardiomyopathy (
ARVC ) and
ventricular tachycardia (
VT ) . -
pubmed
METHODS :
Patients with
ARVC who underwent CE - MDCT followed by endocardial ( n = 30 ) and epicardial ( n = 21 ) electroanatomical mapping ( EAM ) and VT ablation were prospectively enrolled . -
pubmed
Regions with low attenuation likely reflect fibro - fatty involvement in the RV and may serve as important VT substrates in
patients with
ARVC who are undergoing
VT ablation . -
pubmed
Efficacy of a brief mindfulness intervention upon
anxiety in early
psychosis patients . -
pubmed
METHODS : Our study included
patients who had experienced an initial episode of
psychosis , with less than 30 months of antipsychotic exposure . -
pubmed
CONCLUSIONS : A brief mindfulness exercise , conducted in a routine office visit , produced a significant reduction in state
anxiety for early
psychosis patients , regardless of symptom burden . -
pubmed
A wearable resistive
strain sensor that can quickly and precisely detect
human motions like finger bending was fabricated by a 3D printed hydrogel film . -
pubmed
The study model was based on a
PC12 cell line , derived from the
pheochromocytoma of a
rat adrenal medulla , cultured in RPMI 1640 . -
pubmed
Intratracheal injection of
nitric oxide , generated from air by pulsed electrical discharge , for the treatment of
pulmonary hypertension in awake ambulatory
lambs . -
pubmed
RESULTS : In awake
lambs with acute
pulmonary hypertension ,
NO was continuously delivered via the Scoop catheter at 400 ml / min . -
pubmed
CONCLUSIONS : Continuously delivering electrically generated
NO through a Scoop catheter produces vasodilation of the pulmonary vasculature of awake
lambs with
pulmonary hypertension . -
pubmed
Transtracheal
NO delivery may provide a long - term treatment for
patients with chronic
pulmonary hypertension as an outpatient without requiring a mask or tracheal intubation . -
pubmed
The incidence , risk factors , and long - term outcomes of
acute kidney injury in hospitalized
diabetic ketoacidosis patients . -
pubmed
The current study aimed to investigate the incidence rate , risk factors , long - term renal outcomes , and mortality in
DKA patients with
AKI . -
pubmed
METHODS : A total of 179
patients diagnosed with
DKA at Sun Yat - sen Memorial Hospital from January 2012 to January 2018 were included in the analysis . -
pubmed
RESULTS : Among 179
DKA patients , 98
patients ( 54.75 % ) were diagnosed as
AKI . -
pubmed
During follow - up ,
DKA patients with
AKI showed more than a two - fold decline in
eGFR within 1 year after discharge from the hospital when compared with non - AKI
DKA patients . -
pubmed
CONCLUSIONS : Multiple risk factors contribute to the development of
AKI in
DKA patients . -
pubmed
AKI and advanced
AKI stage are associated with rapid progressive
CKD and long - term mortality in
patients with
DKA . -
pubmed
Methods : The study included 539
patients in total , of which 443 had primary
prostate carcinoma and 96
patients had
benign prostatic hyperplasia (
BPH ) . -
pubmed
Background :
Fluoxetine (
FLU ) is the first - line and widely used medication for
depression ; however ,
FLU treatment is almost ineffective in 30%-40 % of
patients with
depression . -
pubmed
Methods : The chronic unpredictable mild stress ( CUMS )
rat model was used to simulate
depression . -
pubmed
Sacubitril /
valsartan reduces mortality in
heart failure with reduced ejection fraction (
HFrEF )
patients , partially due to cardiac reverse remodeling ( RR ) . -
pubmed
We sought to evaluate the rates of left ventricle ( LV ) and left atrial ( LA ) RR through standard and advanced echocardiographic imaging in a cohort of
HFrEF patients , after the introduction of
sacubitril /
valsartan . -
pubmed
We analyzed 77
patients ( 65 + - 11 years old , 78 %
males , 40 %
ischemic etiology ) with 76 ( 28 - 165 ) months since
HFrEF diagnosis . -
pubmed
In
HFrEF patients , despite a long history of the disease , the introduction of
sacubitril /
valsartan provides a rapid global ( i.e. -
pubmed
BACKGROUND : Cognitive function may change over time in
patients with
SLE , and cognitive function trajectories have not well been studied . -
pubmed
METHODS : Residual cytologic fixatives ( n = 42 ) from 39
patients who underwent EUS - FNA for
pancreatic lesions were collected along with demographics , imaging , and laboratory studies . -
pubmed
The comparison between pulmonary rehabilitation with music therapy and pulmonary rehabilitation alone on respiratory drive ,
cortisol level and
asthma control in
patients hospitalized with
asthma exacerbation . -
pubmed
The objective of this interventional double - blinded randomised controlled trial was to assess whether music therapy , as a complementary modality to pulmonary rehabilitation , can help to improve respiratory drive ,
asthma control and quality of life in
patients with
asthma exacerbation . -
pubmed
METHODS : Hospitalized
patients with
asthma exacerbation enrolled in the study were randomly assigned to experimental ( music therapy ) or control ( popular science programme ) group . -
pubmed
Convalescent plasma has been used to treat a number of
infections during pandemics , including
severe acute respiratory syndrome coronavirus (
SARS - CoV ) ,
Middle Eastern respiratory syndrome coronavirus (
MERS - CoV ) and now
severe acute respiratory syndrome coronavirus-2 (
SARS - CoV-2 ) . -
pubmed
SOURCES : A review of articles published in PubMed was performed on 13 July 2020 to summarize the currently available evidence in
human studies for convalescent plasma as a treatment for
coronaviruses . -
pubmed
CONTENT : There were sixteen COVID-19 , four
MERS and five
SARS reports describing convalescent plasma use in
humans . -
pubmed
Adequate treatment options for
patients with advanced
HCC are currently limited . -
pubmed
In vitro cultures of primary
human airway epithelial cells ( hAECs ) grown at air - liquid interface have become a valuable tool to study airway biology under normal and pathologic conditions , and for drug discovery in
lung diseases such as
cystic fibrosis (
CF ) . -
pubmed
The study aims to investigate the effects of
COVID-19 infection with asymptomatic and mild symptoms on trans - myocardial repolarization parameters in
children without treatment . -
pubmed
DESIGN : Six
human tibia plateaus ( 2 healthy , 2 with
osteoarthritis , and 2 with
posttraumatic osteoarthritis ) were used for full - depth cartilage sampling systematically across the joint surface at 12 medial and 4 lateral sites . -
pubmed
Four studies focussed on
human T - cell lymphotropic virus type 1 ( HTLV-1 ) , three studies on
Ebola , and one study on
influenza vaccination . -
pubmed
The potential ability of multi - differentiation and paracrine function of MSCs is bringing new hope to
patients with
male infertility . -
pubmed
ABSTRACT : We describe functional and anatomical imaging findings in an 86 - year - old
woman who was treated for paroxysmal
atrial fibrillation 5 years ago with radiofrequency ablation . -
pubmed
Ultrastructural features of degenerated cardiac muscle cells in
patients with
cardiac hypertrophy . -
pubmed
Degenerated cardiac muscle cells were present in hypertrophied ventricular muscle obtained at operation from 12 ( 38 % ) of 32
patients with
asymmetric septal hypertrophy (
hypertrophic cardiomyopathy ) or
aortic valvular disease . -
pubmed
These observations suggest that degenerated cardiac muscle cells have poor contractile function and may be responsible for impaired cardiac performance in some
patients with chronic
ventricular hypertrophy . -
pubmed
[ Effect of
cyclophosphamide on experimental
tuberculosis in
mice ] . -
pubmed
This clinical use of Gelfoam for temporary rehabilitation is indicated in : 1 ) situations in which
paralysis may be temporary , 2 )
patients for whom an open operative procedure must be delayed , and 3 ) circumstances in which it is desirable to determine the effect of vocal cord injection prior to placement of nonabsorbable material . -
pubmed
The use of blood and blood products for resuscitation of
burn patients is of primary importance in
burn patients . -
pubmed
The extent of
corneal destruction in
rabbit corneas infected with live
Pseudomonas cells was significantly greater in eyes treated with
zinc sulfate than in controls , precluding its use in a clinical setting . -
pubmed
[ Diagnosis of
chronic cholecystitis in
children ] . -
pubmed
[ State of free
amino acid metabolism in
children with
chronic liver diseases ] . -
pubmed
Garlic in
alloxan - induced
diabetic rabbits . -
pubmed
Optimal stimulation of paralyzed muscle after
human spinal cord injury . -
pubmed
Influence of biological variations and sample handling on measured
microalbuminuria in
diabetic patients . -
pubmed
This assay has proven to be valuable for determining the presence of
HCV in various samples ; furthermore , it offers the possibility of diagnosis of
HCV infection in seronegative patients . -
pubmed
None of these
patients experienced
metastases . -
pubmed
Five of these
patients had distant
metastases ( P less than 0.02 ) within 2 years of treatment . -
pubmed
For those
patients at low risk for
relapse , the mean G0 is calculated to be 22.5 , and 13.6 weeks for those who have relapsed or are at high risk for
relapse . -
pubmed
Computed tomography of the brain in the evaluation of the
headache patient . -
pubmed
A retrospective analysis was conducted of 100 consecutive
patients evaluated with computerized tomography of the head who had the chief complaint of
headache . -
pubmed
, as well as from
L1210 (
murine leukemia )
mouse cells was investigated utilizing the technique of the alkaline unwinding of the double stranded DNA molecule . -
pubmed
However , the variability in
infarct size tended to be greater ( P = 0.0647 ) among all
hyperglycemic cats compared to control animals . -
pubmed
Retinal detachments were produced in domestic
cats by injecting fluid between the retinal
pigment epithelium and neural retina . -
pubmed
Subcutaneous instead of intraperitoneal
infection with
T. - pubmed
A
patient was evaluated because of
edema ,
pruritus and generalized painless
lymphadenopathy . -
pubmed
Once he was stable , a laparotomy was performed and the
patient died two days later because of
septic shock . -
pubmed
Construction of viable deletion and insertion mutants of the Sabin
strain of
type 1 poliovirus : function of the 5 ' noncoding sequence in viral replication . -
pubmed
A number of deletion and insertion sequences were introduced into the 5 ' noncoding sequence ( 742 nucleotides long ) of the genome of the Sabin
strain of
type 1 poliovirus by using an infectious cDNA clone of the virus
strain . -
pubmed
A 42 - year - old
man with adult - onset
type III glycogenosis (
Cori ' s disease ) developed a gradually progressive
polyneuropathy with markedly reduced activity of muscle amylo-1,6 - glucosidase and glycogen accumulation within all elements of biopsied sural nerve , including axons , as shown by ultrastructural assessment . -
pubmed
Western blots , using sera from five
patients with
mucormycosis , consistently identified five different determinants in the
R. - pubmed
This suggests that several of the
Rhizopus antigens are present during
mucormycosis . -
pubmed
Enzyme - linked immunosorbent assays of sera from five
patients with
mucormycosis and with
rabbit antisera resulted in antibody titers ranging from 1:64 to 1:32,000 for the
R. - pubmed
37
patients with
muscle disease ( 23
myopathies and 14
neurogenic muscle diseases ) were studied by spiroergometric investigations . -
pubmed
[
Chronic subdural hematoma in
patients over 70 ] . -
pubmed
Suppression of annual plasma
testosterone and
thyroxine cycles in the
edible dormouse Glis glis under constant photoperiod at 24 degrees C. Exposure of male
edible dormice all year round to an unvarying photoperiod and warm temperature disrupted their biological cycles ; hibernation was almost completely suppressed , and short lived infradian cycles of
body weight , and of plasma
testosterone and
thyroxine were measured instead of the normal annual pattern . -
pubmed
Vascular reactivity to
noradrenaline and
5 - hydroxytryptamine in
hypertensive rats . -
pubmed
[ Changes in the
water and
electrolyte content of the blood and muscles in
patients with
shock phenomena ] . -
pubmed
[ Radiological picture of
acute appendicitis in
children ] . -
pubmed
In subgroup 1 ( 40
patients ) , episodes of
non - exertional angina were associated with a pattern of hyperacute
subepicardial injury and , frequently , with
ventricular arrhythmias . -
pubmed
Of these
patients , 25 % developed a
myocardial infarction shortly after admission . -
pubmed
Only 5 % of
patients in this subgroup developed a
myocardial infarction during their hospital stay . -
pubmed
It is concluded that : ( 1 ) observation of the electrocardiogram during
spontaneous angina in
patients with known
atherosclerotic coronary heart disease may be of prognostic significance and may influence therapeutic decision . -
pubmed
A total of 91 multiply resistant bacterial
strains , including
Klebsiella pneumoniae ( 32
strains ) ,
Pseudomonas aeruginosa ( 16
strains ) , and
Serratia marcescens ( 43
strains ) , were collected during hospital epidemics of
nosocomial infection from 1975 to 1979 . -
pubmed
Both
Klebsiella pneumoniae and
Serratia marcescens , including multiply resistant and non - multiply resistant
strains , were most susceptible to the
1 - oxa - beta - lactam LY127935 and
cefotaxime . -
pubmed
All three new
beta - lactams were active against non - multiply resistant
strains of
Escherichia coli ,
Enterobacter spp . ,
Proteus spp . -
pubmed
This belief has persisted despite frequent complaints from
patients with
glaucoma that their central vision is disturbed . -
pubmed
Seventy - eight percent of
patients with early glaucomatous
visual field defects were found to have a
defect in color perception when tested with a desaturated D-15 color panel that tests only the central 1.5 degrees . -
pubmed
Spatial contrast sensitivity appears to be reduced in
patients with
glaucoma . -
pubmed
Indium-111 - labelled
human platelets : a method for use in severe
thrombocytopenia . -
pubmed
We describe and evaluate a simple method for labelling autologous
human platelets with
Indium-111 - oxine in
patients with severe
thrombocytopenia . -
pubmed
Twenty
patients with
immune thrombocytopenia and platelet counts ranging from 5 to 119 X 10(9)/1 were investigated . -
pubmed
This method permits quantitative platelet imaging with autologous labelled platelets in
patients with severe
thrombocytopenia . -
pubmed
Acute surgical abdomen caused by
thrombocytopenia in
patients with
acute leukemia and
multiple myeloma . -
pubmed
One
patient with
multiple myeloma and four
patients with
acute leukemia presented with severe
abdominal pain . -
pubmed
Severe
thrombocytopenia was found in all
patients . -
pubmed
Laparotomy was performed in the
patient with
multiple myeloma , and revealed numerous
petechiae throughout the peritoneum . -
pubmed
All five
patients responded to platelet transfusions with disappearance of the abdominal
signs and symptoms . -
pubmed
Severe
thrombocytopenia should be considered among the causes of acute surgical abdomen in
patients with malignant
hematological disorders , and platelet transfusions should be administered before any surgical intervention . -
pubmed
Experimental
infection in
rabbits evoked by
Pseudomonas aeruginosa ,
Proteus mirabilis ,
Escherichia coli and
Klebsiella pneumoniae treated with
gentamicin ,
amikacin and
sisomicin . -
pubmed
Rabbits were infected with freshly isolated
strains of
Ps . - pubmed
[ The changes on plasma
aldosterone concentration during acute
respiratory acidosis in
dogs . -
pubmed
with a
mouse - adapted
strain of
dengue virus (
DV ) , the following differences were noted in the course of
infection . -
pubmed
It is suggested from these data that the course of
DV infection in
mice is affected by the availability of thymus - derived lymphocytes ( T - cells ) . -
pubmed
The long - term antihypertensive efficacy and tolerability of a fixed combination of
oxprenolol 160 mg slow - release +
chlortalidone 20 mg was studied in 40 out -
patients with mild to moderate
essential hypertension followed during one year with monthly clinical visits . -
pubmed
Results confirm that the fixed combination of
oxprenolol 160 mg slow - release +
chlorthalidone 20 mg is able to long term control mild to moderate
hypertension with a good tolerability , thus allowing an improved
patient compliance . -
pubmed
A noninvasive , zero heat flux method of determining core ( intracardiac blood ) temperature was studied in ten anesthetized
patients having whole body
hyperthermia for the treatment of
cancer . -
pubmed
Over fifty
patients with severe
head injury , and one hundred with
stroke , have now been treated with the competitive
NMDA antagonist
CGS 19755 (
selfotel ) . -
pubmed
For
stroke , however , the maximal tolerated dose was 1.5 mg / kg , because these conscious
patients developed
hallucinations and
agitation . -
pubmed
By extrapolating from
animal studies the " best estimate " would be around 5 mg / kg in
patients with severe
head trauma . -
pubmed
Although several
NMDA antagonists , including
CGS 19755 (
selfotel ) , are currently entering efficacy trials for
stroke , based upon their tremendous potency in
animal models , the problem of psychomimetic effects may necessitate the use of additional management strategies , e.g. -
pubmed
No
cyclosporin - induced
chromosomal aberrations in
human peripheral blood lymphocytes in vitro . -
pubmed
Continuous in vitro treatment of
human peripheral blood lymphocytes with
cyclosporin A for 20 h and 44 h in the absence of metabolic activation decreased the mitotic index in a concentration - dependent way (
MI about 35 % at 50 micrograms / ml ) . -
pubmed
During the past decade , considerable evidence has accrued regarding the immunologic uniqueness of
human milk and of the important role that the immune system in
human milk plays in protecting not only the mature , healthy newborn , but also the premature infant who is more prone to
infections and the damage caused by inflammatory processes . -
pubmed
However , there is a great deal more to learn about the prophylactic and therapeutic uses of
human milk in low
birth weight infants , including ( 1 ) the status of many of the host defense factors in preterm milk , ( 2 ) how to preserve the protective agents in
human milk during processing and storage , ( 3 ) the dose and duration of treatment with
human preterm or mature milk that will be needed to protect against a particular disorder , ( 4 ) whether non - maternal milk is as efficacious as maternal milk for these infants , and ( 5 ) in view of the concern of potential graft versus host reactions , whether it is desirable or contraindicated to maintain the leukocytes in
human milk used to feed premature infants . -
pubmed
The biochemical basis of peritoneal cell
cytotoxicity for
Cryptococcus neoformans was studied by measuring the killing of the
yeast by peritoneal resident cells and peritoneal exudate cells obtained from normal and proteose -
peptone - injected animals , respectively . -
pubmed
All the
children had a huge
abdominal mass but none of them had complete
intestinal obstruction . -
pubmed
Development of
endometrial cancer in
women on
estrogen and
progestin hormone replacement therapy . -
pubmed
The presenting symptoms , hormonal regimens , treatment modalities ,
tumor pathology , and follow - up of 25
women developing
endometrial cancer while receiving postmenopausal
estrogen and
progestin therapy were investigated retrospectively . -
pubmed
Estrogen and
progestin therapy does not prevent
endometrial cancer in all
patients . -
pubmed
Women who developed this
tumor on sequential therapy in general received less than the recommended guidelines for daily dosage and monthly duration of
progestin . -
pubmed
Following a report of the efficacy of total lymphoid irradiation ( TLI ) in the treatment of
chronic progressive multiple sclerosis a further randomised double - blind placebo - controlled study was undertaken with the intention of entering 56
patients . -
pubmed
It was noteworthy that
MCZ was effective for the treatment of deep seated
mycosis and significant effective rate was obtained in the group of
patients who had neutrophils and lymphocytes less than 500 / microliters . -
pubmed
SUBJECTS : 468 survivors of an
acute myocardial infarction ( 289
men and 178
women ) aged 31 - 92 . -
pubmed
We hypothesize , based on the similar localization of
flavin and that of
iron reduction , that the accumulation of
riboflavin sulfates induced by
iron deficiency may be an integral part of the turbo
iron - reducing system in
sugar beet roots . -
pubmed
Distribution of body water in
patients with
cirrhosis : the effect of liver transplantation . -
pubmed
We compared total body water and intracellular - extracellular distribution of body water between male
patients with mild
liver disease without
ascites ( n = 9 ) , male
patients with severe
liver disease and gross
ascites ( n = 6 ) and a group of age- , sex- , height- and weight- matched controls ( n = 6 ) . -
pubmed
We saw no significant difference in total body water between the healthy controls ,
patients without
ascites and
patients with
ascites ( 46.5 + /- 9.2 kg , 45.4 + /- 6.6 kg and 50.4 + /- 5.1 kg , respectively ) , although , as expected , extracellular water was increased in
patients with
ascites compared with healthy controls and
cirrhotic patients without
ascites ( 36.9 + /- 6.5 kg vs. 25.4 + /- 4.4 kg , p = 0.005 ; and 36.9 + /- 6.5 kg vs. 27.0 + /- 5.3 kg , p = 0.002 , respectively ) . -
pubmed
However , intracellular water was significantly reduced in
patients with severe
liver disease compared with that in controls ( 13.6 + /- 3.3 kg vs. 21.5 + /- 4.2 kg , p = 0.005 ) or
patients without
ascites ( 13.6 + /- 3.3 kg vs. 18.3 + /- 2.9 kg , p = 0.01 ) . -
pubmed
A 60 - year - old female
patient presenting with
anemia was found to have a left - sided
renal tumor and a contralateral adrenal mass of 2 cm in diameter . -
pubmed
The case illustrates that surgery of solitary
metastases from
renal cell carcinoma may be beneficial to the
patient . -
pubmed
METHODS : Twenty - two healthy , slightly
overweight , sedentary , normotensive , normolipemic
men , age 22 to 44 years , were randomly assigned to an exercise or control group for 12 weeks followed by a 4 - week washout period . -
pubmed
The case presented is an example of an acute
gastric volvulus in a 2 - year - old male child affected by a
diaphragmatic defect The peculiar aspect of this case consists in the age of arousal being more usual in an earlier age An appropriate surgical treatment has permitted the
patient 's recovery . -
pubmed
Mechanisms of selective motor neuron
death in
ALS : insights from transgenic
mouse models of
motor neuron disease . -
pubmed
Concerning the mechanism(s ) of disease underlying
amyotrophic lateral sclerosis (
ALS ) , transgenic
mouse models have provided ( i ) a detailed look at the pathogenic progression of disease , ( ii ) a tool for testing hypotheses concerning the mechanism of neuronal
death , and ( iii ) a host appropriate for testing therapeutic strategies . -
pubmed
Diversion - related experimental
colitis in
rats . -
pubmed
The aim of the present study was to create an experimental model of diversion - related
colitis in
rats , so in the future it will be possible to test different hypotheses . -
pubmed
RESULTS : Exclusion was associated with
vascular congestion , a decrease in length of glandular crypts ( P & lt ; 0.01 ) , and an erosion of surface epithelium ;
inflammation of the mucosa was absent in all control
animals and present in all test
animals . -
pubmed
CONCLUSION : This experimental model of diversion
colitis is characterized by histologic and bacteriologic modifications comparable with those reported in
humans but with different histochemical changes . -
pubmed
We therefore compared the effects of daily variations in particles of different sizes on peak expiratory flow ( PEF ) during a 57 - day follow - up of 39
asthmatic children aged 7 - 12 years . -
pubmed
Women with
silicone gel - filled breast implants ( SBIs ) are likely to be at a slightly higher risk of developing an
autoimmune - like syndrome . -
pubmed
RESULTS AND CONCLUSIONS : Cross sectional study : In the 73
children aged 3 years who attended nursery schools , 7 cases of
enuresis ( 9.6 % ) were identified . -
pubmed
Visual - induced postural sway in
children with and without
otitis media . -
pubmed
Children with
otitis media with
effusion (
OME ) have been shown to have a significantly higher velocity of sway than normal children . -
pubmed
Further studies are needed to define the role of vestibular function in the management of
children with
OME . -
pubmed
We report about 38
patients aged between 1 and 19 years ( 36.8 % female , 63.2 % male ; mean age 7.8 years ) admitted as inpatients for further neurorehabilitation mostly 4 weeks after severe
acquired brain injury (
ABI ) of different aetiology . -
pubmed
Dietary supplementation of deficient substrates (
arachidonic acid or
myo - inositol ) , either in vitro or in vivo , has been shown to reduce the incidence of
diabetes - related malformations in offspring of
diabetic pregnant
animals . -
pubmed
We determined the prevalence of
rheumatoid nodules of finger tendons in
patients with
RA , using high frequency linear transducers with high resolution ultrasonography . -
pubmed
METHODS : The study comprised 54 consecutive
patients with
RA and 20 controls . -
pubmed
All 25
patients studied became culture - negative within 2 months of initiation of therapy for
tuberculosis and remained negative for a median of 13 months follow - up after completion of therapy . -
pubmed
In summary , the concomitant use of
rifabutin and HAART can lead to successful treatment of
HIV - infected patients with
tuberculosis without increased side effects . -
pubmed
Effect of
niacin on lipid and lipoprotein levels and glycemic control in
patients with
diabetes and
peripheral arterial disease : the ADMIT study : A randomized trial . -
pubmed
OBJECTIVE : To determine the efficacy and safety of lipid - modifying dosages of
niacin in
patients with
diabetes . -
pubmed
PARTICIPANTS : A total of 468
participants , including 125 with
diabetes , who had diagnosed
peripheral arterial disease . -
pubmed
INTERVENTIONS : After an active run - in period ,
participants were randomly assigned to receive
niacin ( crystalline
nicotinic acid ) , 3000 mg / d or maximum tolerated dosage ( n = 64 with
diabetes ; n = 173 without
diabetes ) , or placebo ( n = 61 with
diabetes ; n = 170 without
diabetes ) for up to 60 weeks ( 12 - week active run - in and 48 - week double - blind ) . -
pubmed
After
sterility testing and quantity analysis of the residual contrast in 28 vials , this method was successfully used in 10
patients . -
pubmed
Because
macrocephaly could be a sign of abnormal brain development and because 30 % to 50 % of
children with
NF-1 display
macrocephaly in the absence of
hydrocephalus , we sought to determine the relationship between
macrocephaly and other
brain abnormalities in young
subjects with
NF-1 . -
pubmed
These
subjects were free of
brain tumor ,
epilepsy , or other obvious neurologic problems . -
pubmed
RESULTS : Cranial circumference was 2 or more SDs above the age norm in seven ( 39 % ) of 18
subjects , a frequency of
macrocephaly 17 - fold higher than normal . -
pubmed
Conventional MR imaging showed abnormalities in all 18
children , although there were more extensive abnormalities in subjects with
macrocephaly . -
pubmed
Use of
Taenia crassiceps cysticercus antigen preparations for detection of antibodies in cerebrospinal fluid samples from
patients with
neurocysticercosis (
Taenia solium ) . -
pubmed
Using immunoblotting of the three antigens , low - molecular - mass peptides ( 18 and 14 kDa ) were characterized only in cerebrospinal fluid samples from
patients with
neurocysticercosis . -
pubmed
RESULTS : Both
retroviral and
adenoviral vector - mediated transduction of the dCK complementary DNA resulted in marked sensitization of
tongue squamous carcinoma cell lines to the
cytotoxic effects of
cytarabine in vitro . -
pubmed
Carriage rates for
DCC children and controls were 58 and 37 % for
S. - pubmed
METHODS : A 28 - year - old
female presented with
nodular scleritis in the right eye and
left orbital inflammation lasting 1 year . -
pubmed
The
patient initially responded to systemic
steroids , but then
ocular inflammation became more severe , associated with onset of
fever ,
myalgias , and elevation of the erythrocyte sedimentation rate , accompanied by formation of multiple
cutaneous abscesses . -
pubmed
RESULTS : The diagnosis of
pyoderma gangrenosum was made 1 year after the occurrence of ocular symptomatology , when the
patient presented with
ocular and skin lesions and
abscesses in the spleen and liver . -
pubmed
Thromboembolic complications are often seen in
patients with
nephrotic syndrome . -
pubmed
In these
patients , there is evidence of endothelial cell
injury and probably secondary activation of the coagulation cascade . -
pubmed
Four of these compounds ( 2 - 5 ) exhibited moderate
cytotoxicities against
human colon carcinoma and
human lung carcinoma cell lines with IC(50 ) 's ranging from 2 to 25 microg / mL. -
pubmed
Epileptiform abnormalities in
children with
attention - deficit - hyperactivity disorder . -
pubmed
Enhanced protection against the migratory phase , but defective protection against the intestinal phase of
Strongyloides venezuelensis infection in
cotton rats ,
Sigmodon hispidus . -
pubmed
The protective capacity of the
cotton rat ,
Sigmodon hispidus , against the migratory and intestinal phases of
Strongyloides venezuelensis infection was examined . -
pubmed
To determine whether this enhanced protection was expressed during the migratory phase or the intestinal phase , larval recovery from the lungs of cotton
rat was evaluated 3 days after subcutaneous L(3 )
infection . -
pubmed
For the study of the
hepatitis E virus infection animal model , two
chimpanzee were inoculated with
hepatitis E virus . -
pubmed
[ Laparoscopic and classic cholecystectomy in
patients with
liver cirrhosis ] . -
pubmed
PATIENTS AND METHODS : Sixty seven
patients with
gallstones with well - documented
cirrhosis undergoing cholecystectomy ( laparoscopic cholecystectomy ( LC ) in 35 and open cholecystectomy ( OC ) in 32 ) , were studied . -
pubmed
In the LC group , 26 were classified as Child - Pugh class A , 8 as Child 's B class and 1 as Child 's class C. In the OC group , 12 were classified as Child 's class A , 15 as Child 's B and 5 as Child 's C. RESULTS : Complications occurred in 4 of 35 ( 12.3 % )
LC patients ( 1
patients was Child A and 3 were B ) . -
pubmed
CONCLUSIONS : LC has a lower rate of complications than
OC and is a reasonable option for Child 's class A and B
patients with
cirrhosis and
gallstones . -
pubmed
This finding provides insight into the etiology of
cancer and the differences between genes involved in
cancer and those implicated in other
human diseases . -
pubmed
Specifically , we found a significant overlap between human oncogenes and
tumor suppressor genes and " essential genes , "
human homologs of
mouse lethal genes identified by knockout experiments . -
pubmed
In the present paper , our aims were 1 ) to establish a new method to produce antihypertensive peptides ( AHP ) , and 2 ) to study the expression profiles of different host
strains (
Escherichia coli JM109 and DH5alpha ) . -
pubmed
Twenty hips of 19
patients with comminuted
fractures or
nonunion of the greater trochanter were stabilized with tension band technique . -
pubmed
The
patient has abductor
weakness with Trendleburg limp but without
pain . -
pubmed
Six
patients developed grade 1
heterotopic ossification and two
patients grade 3 . -
pubmed
None of the 19
patients experienced a
dislocation during the follow - up . -
pubmed
Of the three
cows that reached the third trimester , one recipient died of
hydrallantois 2 months before term , one aborted fetus was recovered at 8 months of gestation , and one delivered by cesarian section a healthy cloned calf . -
pubmed
Interestingly , Todd was the first to present an electrical theory of
epilepsy , supported by his own
animal experimentation , well before his better - known successor John Hughlings Jackson ( 1835 - 1911 ) ( famous for his investigations of partial
epilepsies and the eponymous " Jacksonian march " ) . -
pubmed
Four
patients from group P and none from group D reached an end - point of the study (
oliguria ,
renal dysfunction ) and received
dopamine . -
pubmed
Hepatitis B virus (
HBV ) is one of the major causes of
liver disease worldwide . -
pubmed
MATERIALS AND METHODS : Fifteen nodules of between 0.5 - 1.5 cm were localised in fifteen
patients , of whom ten had antecedents of
neoplasia , with the placement of spiral harpoon model Somatex , of 120 mm length and 18 G of Laboratorios Leleman , S.L. -
pubmed
COPD patients
Streptococcus pneumoniae vaccination give better pharmacoeconomic results in higher age - groups . -
pubmed
Specific attention has been directed toward the beneficial effects afforded by dietary antioxidants , in particular those from
fruit and
vegetables , in ameliorating age - related
deficits in brain performance . -
pubmed
OBJECTIVES : To report one case of
precocious puberty in a 6 - year - old
boy with
bilateral cryptorchidism . -
pubmed
CONCLUSIONS :
Genital ambiguity should be considered when evaluating a
boy without palpable gonads . -
pubmed
Diabetes was induced in New Zealand male
rabbits with a single dose of
alloxan ( 100 mg / kg , i.v . ) -
pubmed
Silent
cerebral infarction in
patients with
dilated cardiomyopathy : echocardiographic correlates . -
pubmed
BACKGROUND :
Patients with
dilated cardiomyopathy (
DCM ) have an increased risk of
thromboembolic events . -
pubmed
Incidence of silent
cerebral infarction (
SCI ) has not been investigated in these
patients . -
pubmed
The aim of this study was to investigate the incidence of
SCI in
patients with
DCM and to determine its associations with echocardiographic parameters . -
pubmed
METHODS AND RESULTS : Seventy - two
patients ( mean age 62+/-12 years ) with
DCM underwent cranial magnetic resonance imaging in addition to transthoracic and transesophageal echocardiographic examination . -
pubmed
A total of 56 age - matched healthy
volunteers served as a control group for comparison
SCI prevalence . -
pubmed
Prevalence of
SCI was significantly higher in
patients with
DCM ( 35 % vs. 3.6 % ; p<0.001 ) . -
pubmed
In
DCM group ,
patients with
SCI had significantly
impaired left ventricular systolic function , higher frequency of restrictive diastolic filling , moderate to severe left atrial spontaneous echo contrast ( SEC ) , aortic SEC , and complex
atherosclerosis or
calcified plaques in the aorta . -
pubmed
CONCLUSION :
SCI is a frequent finding in
DCM patients . -
pubmed
Necrotic dermatitis in
chickens . -
pubmed
Common
malignant musculoskeletal neoplasms of
dogs and
cats . -
pubmed
Malignancies of the musculoskeletal system in
dogs and
cats can be categorized as either primary or metastatic within the bony or soft structures that comprise the musculoskeletal system . -
pubmed
By far , the most common
tumor that affects the musculoskeletal system in
dogs is
osteosarcoma . -
pubmed
The most common
tumors that affect the musculoskeletal system in
cats are
injection site sarcomas . -
pubmed
These
tumors are locally infiltrative ; whereas up to 25 % metastasize , most
animals die from our inability to control local disease . -
pubmed
Only by recognizing these
patients as early as possible we will be able to reduce morbidity and mortality of this potentially dangerous
syndrome . -
pubmed
Administration of statins in combination with
osteoporosis therapy appears to improve alveolar bone architecture in the mandibles of OVX
rats with maxillary molar extraction . -
pubmed
Statins continue to be considered as potential therapeutic agents for
patients with
osteoporosis and possibly with
periodontal disease . -
pubmed
Perceptuomotor functioning in preschool
children with symptoms of
attention deficit hyperactivity disorder . -
pubmed
Given limited research on perceptual - motor functioning of preschool
children with symptoms of
ADHD , the purpose of this study was to compare the fine motor , gross motor , visuomotor , and oral - motor functioning of 49 4- to 6 - yr.-old
children with symptoms of
Attention Deficit Hyperactivity Disorder and 48 typically developing
children . -
pubmed
The method is verified with simulated data and demonstrated with experimental data from 2 studies , one clusters with respect to severity of
disease in
Alzheimer 's patients and another clusters data for a
rat fracture healing study over time . -
pubmed
These involves occupational risk factors as well as classic ones , such as
obesity , limited physical activity or
tobacco smoking . -
pubmed
When OBP-401 was intratumorally injected into
HT29 tumors orthotopically implanted into the rectum in
BALB / c nu / nu mice , para - aortic lymph node
metastasis could be visualized at laparotomy under a three - chip color cooled charged - coupled device camera . -
pubmed
Ticks removed from 1136
dogs and 134
cats all over Japan were examined for
Borrelia infection by PCR and sequencing . -
pubmed
[ Electrode grids are available for the selection of
patients with refractory
epilepsy for
epilepsy surgery ] . -
pubmed
In 60 - 85 % of
patients with
refractory epilepsy , surgical excision of that part of the brain that is considered to be responsible for the development of
epileptic seizures leads to the disappearance of the attacks . -
pubmed
In the Netherlands , 60 - 70
patients undergo
epilepsy surgery every year ; this is a small number in comparison to the number of potential candidates . -
pubmed
Patients with medically refractory
epilepsy without structural damage on the MRI or with a lesion in or near specialised areas of the cortex could also be examined and then treated surgically . -
pubmed
Effect of
atorvastatin withdrawal on circulating
coenzyme Q10 concentration in
patients with
hypercholesterolemia . -
pubmed
Coenzyme Q10 depletion has been speculated to play a potential role in
statin - related adverse events , and withdrawal of statin is the choice in
patients developing
myotoxicity or
liver toxicity . -
pubmed
Twenty - six
patients with
hypercholesterolemia received
atorvastatin at 10 mg / day for 3 months . -
pubmed
METHODS : A 41 - year - old nulliparous
woman presented with
urinary incontinence following an abdominal hysterectomy , and office evaluation identified a
vesicovaginal fistula . -
pubmed
CONCLUSIONS : The robotic - assisted laparoscopic approach is a viable option for successful repair of a
vesicovaginal fistula in a
patient in whom a vaginal approach is not indicated . -
pubmed
RESULTS : A 70 - year - old Japanese
man was referred to the authors because of poorly controlled
hypertensive keratouveitis in the left eye . -
pubmed
The
patient had a history of recurrent
hypertensive anterior uveitis . -
pubmed
The aqueous humor was investigated for
herpes simplex virus ,
varicella - zoster virus and
cytomegalovirus . -
pubmed
Children scored 0.38 ( 95 % confidence interval 0.09 - 0.68 ) points higher on duration of orienting per SD decrease in total body
weight gain from mid - pregnancy to birth . -
pubmed
These results in
mice suggest that stress exposure during adolescence may increase the risk for developing an
alcohol - use and/or
anxiety disorder in
individuals with a
genetic predisposition toward high
alcohol consumption . -
pubmed
Morphology of exertion - triggered
plaque rupture in
patients with
acute coronary syndrome : an optical coherence tomography study . -
pubmed
The aim of the present study was to use optical coherence tomography to investigate the relationship in
patients with ACS between the morphology of a
ruptured plaque and the
patient 's activity at the onset of
ACS . -
pubmed
METHODS AND RESULTS : The study population was drawn from 43 consecutive
ACS patients ( with or without ST - segment elevation ) who underwent optical coherence tomography and presented with a ruptured
plaque at the culprit site . -
pubmed
The purpose of our current study was to determine the effects of a novel combination of herbal extracts on intestinal
inflammation using a
murine model of
IBD . -
pubmed
Female
Swiss - Webster mice were randomized to receive normal water or 5 %
dextran sulfate sodium ( DSS ) drinking water to induce
colitis . -
pubmed
Motor and sensory assessment of
patients in clinical trials for pharmacological therapy of acute
spinal cord injury : psychometric properties of the ASIA Standards . -
pubmed
The 2000 version of the ASIA Standards appear to be more reliable than the previous versions , although two prospective studies indicate that the ASIA Standards do not reliably assess
children less than 4 years with
SCI . -
pubmed
PURPOSE : We evaluated clinicopathological features and outcomes in
patients with
penile squamous cell carcinoma . -
pubmed
A 42 year - old
woman develops
steroid refractory
graft - versus - host disease (
GVHD ) after second allogeneic stem cell transplantation for
acute myelogenous leukemia with severe
GVHD of her skin with
blisters , severe
GVHD of her gut with watery and bloody
diarrhea and
GVHD of her liver with
cholestasis . -
pubmed
We evaluated 70
melanomas from 70
patients seen at a single institution from 1997 to 2008 . -
pubmed
METHOD : Twelve
adults with persistent
stuttering and 12 adults who had never stuttered each completed 4 ABA - format experiments . -
pubmed
We report a case of acute
carpal tunnel syndrome caused by
periarticular calcification (
hydroxyapatite deposition disease ) around the wrist joint in a 64 - year - old
woman . -
pubmed
Obtaining normal tissue constraints using intensity modulated radiotherapy ( IMRT ) in
patients with
oral cavity , oropharyngeal , and laryngeal carcinoma . -
pubmed
The mandibular constraints were met in 66 % , 29 % , and 57 % of
patients with
oral , oropharyngeal , and laryngeal cancers , respectively . -
pubmed
Every experiment with the contents of one , or with those pooled from two to five of the normal stock of Rockefeller Institute
strain of albino
mice , 1 to 2 months of age , revealed the presence of a virus which , after intracerebral inoculation into normal
mice , induced characteristic
paralytic encephalomyelitis , indistinguishable from Theilerapos;s disease . -
pubmed
No difference was seen in this effect of intestinal contents deriving from animals paralyzed during the course of spontaneous
encephalomyelitis and from normal
mice . -
pubmed
The present , as well as previous work has shown that the virus found in normal ( or paralyzed )
mice is similar to that of
Theiler ' s disease in all of its properties thus far investigated ; among the
strains of the latter now at hand it can be classified with those having a low degree of invasiveness after peripheral inoculation . -
pubmed
Our previous study showed that the high level of
OTA contamination in
wheat might be related to the high incidence of
gastric carcinoma in rural area of China . -
pubmed
In the present study , we explored the
toxicity of
OTA in
human gastric epithelium immortalized cells (
GES-1 ) by analyzing the regulation of the cell cycle , apoptosis and its molecular mechanism . -
pubmed
Further studies to explore the effectiveness of these methods and to motivate gachhis to invest their time and money to use them could reduce the risk of
human Nipah infection in Bangladesh . -
pubmed
It is a prototype of postinfectious
autoimmune disease , whose pathophysiology is well described in the forms provoked by certain bacteria ( molecular mimicry with
Campylobacter jejuni ) , but remains unclear for the forms related to other organisms ( cytomegalovirus ,
Epstein - Barr virus and other
herpes group viruses ,
Mycoplasma pneumoniae ) . -
pubmed
We report the observation of a 12 - year - old
girl who presented with
Guillain - Barre syndrome with
facial diplegia ,
ataxia , and
intracranial hypertension following
Epstein - Barr virus ( EBV ) primary infection . -
pubmed
EBV might be the factor that triggered the
autoimmune disorders , as previously reported for
systemic lupus erythematosus and
multiple sclerosis in children . -
pubmed
Microbicide excipients can greatly increase susceptibility to
genital herpes transmission in the
mouse . -
pubmed
BACKGROUND : Several active ingredients proposed as vaginal microbicides have been shown paradoxically to increase susceptibility to
infection in
mouse genital herpes ( HSV-2 ) vaginal susceptibility models and in clinical trials . -
pubmed
Twelve hours after exposure to the excipient or a control treatment ,
mice were challenged with a vaginal dose of
HSV-2 , and three days later were assessed for
infection by vaginal lavage culture to assess susceptibility . -
pubmed
BACKGROUND / AIMS : The aim was to describe the factors determining total pubertal growth ( TPG ) in
adolescents with
growth hormone deficiency (
GHD ) ,
Turner syndrome (
TS ) , who were small for gestational age ( SGA ) or had
idiopathic short stature ( ISS ) . -
pubmed
One
patient ( 4 % ) developed a retroperitoneal
haematoma and required blood transfusion and one had
haematuria that prolonged hospital stay by 2 days . -
pubmed
Here we applied tensor - based morphometry to brain magnetic resonance imaging scans of 732 elderly
individuals from the
Alzheimer ' s Disease Neuroimaging Initiative study , to determine associations between
homocysteine and
brain atrophy . -
pubmed
This association was also found when considering mild
cognitive impairment individuals separately . -
pubmed
METHODS : The effect of developing postoperative renal risk ,
injury or failure as defined by the RIFLE criteria on the long - term survival of
patients undergoing isolated CABG with a normal renal function was studied . -
pubmed
46.5 % of
patients had
chronic kidney disease (
CKD ) stage 1 (
GFR & gt;=90 ml / min/1.73 m(2 ) ) , 50.4 % had
CKD stage 2 (
GFR 60 - 89 ml / min/1.73 m(2 ) ) and 3.1 % had
CKD stage 3 (
GFR 30 - 59 ml / min/1.73 m(2 ) ) on admission , despite having a normal serum
creatinine . -
pubmed
In
patients with normal preoperative serum
creatinine , Cox regression analysis revealed that age ( P = 0.026 ) , preoperative
creatinine ( P = 0.006 ) and logistic EuroSCORE ( P & lt ; 0.0001 ) were significant factors in addition to the development of postoperative renal risk ,
injury or failure ( P & lt ; 0.0001 ) , with regard to determining long - term survival . -
pubmed
In
patients with a preoperative GFR & gt;90 ml / min , Cox regression analysis revealed that
diabetes ( P = 0.004 ) sex ( P = 0.019 ) and logistic EuroSCORE ( P & lt ; 0.0001 ) , were also significant factors in addition to the development of postoperative renal risk ,
injury or failure ( P = 0.0001 ) with regard to determining long - term survival . -
pubmed
Second - generation antipsychotics ( SGAs ) are increasingly being used to treat
children with a variety of
psychiatric illnesses . -
pubmed
The
patient underwent a pterional craniotomy for surgical clipping of
aneurysms associated with the
AVM . -
pubmed
Homeopathic treatment of
migraine in
children : results of a prospective , multicenter , observational study . -
pubmed
OBJECTIVES : The study objective was to evaluate the effectiveness of homeopathic medicines for the prevention and treatment of
migraine in
children . -
pubmed
SUBJECTS : Fifty - nine ( 59 ) physicians trained in the prescription of homeopathic medicines and 168
children , aged 5 - 15 years , with definite or probable
migraine diagnosed using International
Headache Society 2004 criteria were the subjects in this study . -
pubmed
CONCLUSIONS : The results of this study demonstrate the interest of homeopathic medicines for the prevention and treatment of
migraine attacks in
children . -
pubmed
Recent epidemiological studies have indicated that at least one in every 100
people has some form of
ASD . -
pubmed
Acute
pancreatitis was induced in
rats by clamping of inferior splenic artery for 30 min followed by reperfusion . -
pubmed
Graded
stenoses and total vessel occlusion of the carotid , aorta , and femoral arteries were created in 25
Wistar rats . -
pubmed
Our perspective is that current studies on genes , environment , and immunity in this disease provides us with a great outlook to investigate interesting general aspects of autoimmunity and development of
human autoimmune disease -- in addition to the opportunity to better understand , prevent , and ultimately treat
RA . -
pubmed
METHODS : One hundred and thirty - three
patients with a poor
PS ( Eastern Cooperative Oncology Group 3 or 4 ) were treated with palliative RT using the three - dimensional conformal technique and retrospectively analyzed . -
pubmed
Grade 3 acute
toxicity was observed in two
patients ( 2 % ) and Grade 2 acute toxicity was observed in 10
patients ( 9 % ) . -
pubmed
No Grade 2 or higher late toxicities were observed , except for Grade 3 radiation
pneumonitis in one
patient . -
pubmed
The palliative effect is strongly correlated with prolongation of the survival time and may contribute to improving the remaining survival time in
patients with metastatic / advanced
cancer with a poor PS . -
pubmed
Detection of DNA in hair could be , therefore , a useful tool to chronologically record the
infection process during experimental
mice assays . -
pubmed
Adapalene 0.3 % for the treatment of
acne in
women . -
pubmed
Design / objective : In this analysis , data from two studies comparing
adapalene gel 0.3 % to vehicle gel were combined and evaluated for change in lesion counts and Investigator 's Global Assessment of success rates in adult female
subjects ages 18 to 41 years with
acne vulgaris . -
pubmed
CONCLUSION : In this subgroup analysis ,
adapalene gel 0.3 % proved effective and well tolerated in adult
women with
acne vulgaris . -
pubmed
OBJECTIVE : This study examined 1 ) the extent to which
cocaine - dependent and non - addicted
individuals differed on measures of intrinsic connectivity during fMRI Stroop performance ; and 2 ) the relationships between fMRI Stroop intrinsic connectivity and treatment outcome in
cocaine dependence . -
pubmed
CASE REPORT : A 54 - year - old
woman was referred to us for
cataract surgery in her left eye . -
pubmed
Acute
toxicity of multi - walled
carbon nanotubes ,
sodium pentachlorophenate , and their complex on earthworm
Eisenia fetida . -
pubmed
The acute
toxicities of MWCNTs and
PCP - Na on earthworm
Eisenia fetida were studied through different exposure methods ( filter paper contact test , immersion contact test , and artificial soil contact test ) . -
pubmed
Our results indicated that the
toxicity of
PCP - Na on
E. - pubmed
Transcranial direct current stimulation ( tDCS ) is a non - invasive neuromodulatory technique that can affect
human pain perception . -
pubmed
The present study investigated whether short - term tDCS reduced heat
pain intensity , stress , blood pressure and increased heat
pain thresholds in healthy
volunteers when controlling for placebo effects . -
pubmed
A total of 203 consecutive
patients with acute
PE were included . -
pubmed
The RDW was higher in the
CTEPH patients than the
patients without
CTEPH ( 17.04 + - 3.46 , 14.64 + - 1.82 , respectively , p = 0.015 ) . -
pubmed
RDW was also higher in the
CTEPH patients at the time of diagnosis of
CTEPH during follow - up compared with the baseline RDW level at the time of PE diagnosis ( 18.63 + - 3.58 , 17.02 + - 3.59 , respectively , p = 0.014 ) . -
pubmed
Although gray matter changes have been documented to be predictive of cognitive decline culminating in
AD among healthy older
adults , very little attention has been given to alterations in white matter as a possible MRI biomarker predictive of
AD . -
pubmed
In this investigation , we examined parahippocampal white matter ( PWM ) volume derived from baseline MRI scans in 2 independent samples of 65 cognitively normal older
adults , followed longitudinally , to determine if it was predictive of
AD risk . -
pubmed
PURPOSE : To report the relative frequency of presenting signs in Tunisian
children with
retinoblastoma and to evaluate their prognostic impact . -
pubmed
METHODS : A retrospective study was undertaken of 200
patients with
retinoblastoma examined and treated between January 1993 and June 2009 . -
pubmed
Nineteen
children ( 9.5 % ) had a family history of
retinoblastoma . -
pubmed
In our series , 26
children ( 13 % ) presented with
extraocular retinoblastoma . -
pubmed
Human papillomavirus - related cell cycle markers can predict survival outcomes following a transoral lateral oropharyngectomy for
tonsillar squamous cell carcinoma . -
pubmed
OBJECTIVES : To identify the prognostic implications of
human papillomavirus ( HPV)-related cell cycle marker profiles in
patients who have received a transoral lateral oropharyngectomy ( TLO ) as a primary treatment for
tonsillar squamous cell carcinoma (
TSCC ) . -
pubmed
CONCLUSION :
HPV - related cell cycle markers may also be good indicators for predicting survival after TLO for
TSCC . -
pubmed
Nine
patients were excluded for known
prostate cancer . -
pubmed
Six ( 10 % )
patients were diagnosed with
urinary tract infection . -
pubmed
Qingyihuaji formula ( QYHJ ) , a traditional Chinese medicine , acts as an independent protective factor for
pancreatic cancer patient survival and different
patients have shown various responses to QYHJ treatment . -
pubmed
Pituitary imaging findings in male
patients with
hypogonadotrophic hypogonadism . -
pubmed
CONTEXT : Data on pituitary imaging in adult male
patients presenting with
hypogonadotrophic hypogonadism (
HH ) and no known
pituitary disease are scarce . -
pubmed
OBJECTIVE : To assess the usefulness of pituitary imaging in the evaluation of
men presenting with
HH after excluding known
pituitary disorders and
hyperprolactinemia . -
pubmed
DESIGN : A historical prospective cohort of
males with
HH . -
pubmed
Microadenoma was found in 8 ( 10.7 % ) , empty sella and thickened pituitary stalk in one
patient ( 1.3 % ) each . -
pubmed
Testicular tumors are very common among
man under the age of 45 years . -
pubmed
The recipient 's antibodies against the graft
human leukocyte antigens are responsible for antibody mediated graft
injury . -
pubmed
Roughly half of the
femoral fracture patients diagnosed with
AFF according to the criteria suggested by a task force of the American Society for Bone and Mineral Research ( ASBMR ) have not undergone
bisphosphonate ( BP ) therapy . -
pubmed
We report a case of an 84 - year - old
woman with
AFF not treated by BP therapy , in whom underlying
osteomalacia was histologically diagnosed . -
pubmed
Patients with
congeni - tal LLD treated with combined method of treatment had benefit from intramedullary alignment due to its better outcome . -
pubmed
In vivo studies in Ehrlich ascites
tumor bearing
Swiss albino mice showed enhanced antitumor efficacy and minimal
cardiotoxicity of polymersomes with ~90 %
tumor regression as compared to ~38 %
tumor regression observed with free
doxorubicin . -
pubmed
UNLABELLED :
Toxoplasmosis is a
zoonotic parasitic disease caused by protozoan ,
Toxoplasma gondii . -
pubmed
Infections of
human are common and are usually asymptomatic but it is so dangerous in immunosuppressed and
HIV positive patients . -
pubmed
RESEARCH DESIGN : Eighteen participants with
TBI ( seven
females ) and 19 healthy comparison participants ( CP ; eight
females ) engaged in a 10 - minute conversation with an unfamiliar partner . -
pubmed
METHODS : Resistance vessels from
patients with ( n=12 ) and without ( n=13 )
chronic kidney disease were incubated in normal or high
phosphate . -
pubmed
In a high
phosphate environment , endothelial and
vascular dysfunction is evident in blood vessels and in
man exposed to prolonged oral
phosphate loading . -
pubmed
Symptom - Based Treatment of
Neuropathic Pain in
Spinal Cord - Injured Patients : A Randomized Crossover Clinical Trial . -
pubmed
OBJECTIVE : The objective of this study was to identify the differences in medication effect according to
pain characteristics in
spinal cord - injured patients . -
pubmed
Fifty - five
patients and 66 locations of
neuropathic pain were included . -
pubmed
Patients were divided into two groups : evoked
pain present and evoked
pain absent . -
pubmed
RESULTS :
Oxcarbazepine was significantly more effective for
patients without evoked
pain than in those with it for electrical , burning , and pricking
pain . -
pubmed
In
patients with evoked
pain ,
pregabalin was shown to be significantly more effective for electrical
pain ,
allodynia , and heat
hyperalgesia than
oxcarbazepine . -
pubmed
[ COMPARATIVE EFFECTIVENESS AND SAFETY OF NEW ORAL ANTICOAGULANTS AND
WARFARIN IN
PATIENTS WITH AGE - SPECIFIC
NON - VALVULAR ATRIAL FIBRILLATION ] . -
pubmed
The treatment of
patients aged 65 - 74 and 75 - 80 yearsfor 2 years with
dab itragan ( 110 mg b.i.d ) ,
apixaban ( 5 mg b. i. d ) , and
rivaroxaban ( 20 mg once daily ) prevented
stroke as effectively as
warfarin therapy but less frequently caused severe
intracranial hemorrhage . -
pubmed
It is concluded that these new anticoagulants can be used as alternative medication for antithrombotic therapy of elderly
patients with age - specific
non - valvular atrialfibrillation . -
pubmed
BACKGROUND :
Patients with
nonvalvular atrial fibrillation (
AF ) who undergo electrical cardioversion ( ECV ) tend to be younger and have less comorbidity . -
pubmed
METHODS AND RESULTS : From January 2008 to June 2012 , 571 ECV were performed in 406 consecutive
patients with
nonvalvular AF . -
pubmed
The purpose of this study was to evaluate this cortical and subcortical vascular hypointensity (
CSVH ) in
patients with
moyamoya disease . -
pubmed
METHODS :
Subjects were 20 consecutive
patients with
moyamoya disease . -
pubmed
The numbers of
CSVH in each hemisphere were counted and the numbers were compared between
patients with
moyamoya disease and controls . -
pubmed
RESULTS :
Patients with
moyamoya disease had significantly more CSVH in the middle cerebral artery territory ( p & lt ; 0.001 ) and the anterior cerebral artery territory ( p & lt ; 0.001 ) compared with controls . -
pubmed
The purpose of the present work was to study the cellular functions of endothelial and smooth muscle cells from the
patients with
aneurysms of the thoracic aorta . -
pubmed
We studied endothelial and smooth muscle cells from
aneurysms in
patients with
bicuspid aortic valve and with tricuspid aortic valve . -
pubmed
To evaluate the potential contribution of miRNAs in acquired resistance to
cisplatin in
pancreatic cancer , we compared levels of more than 2000
human miRNAs in a
cisplatin - resistant cell line (
BxPC3 - R ) derived from parental (
BxPC3 ) cells by step - wise exposure to increasing concentrations of the drug over more than 20 passages . -
pubmed
Men with
hypertension , recent
fever , chemo or radiation exposure were excluded from the study . -
pubmed
OBJECTIVES : This study evaluated the efficacy of
ramelteon for
insomnia in adult
subjects with
ADHD . -
pubmed
CONCLUSIONS :
Ramelteon is efficacious in maintaining an earlier sleep / wake cycle in
adults with
ADHD and
CRSD but can have paradoxical fragmenting effects on sleep and exacerbate
daytime sleepiness . -
pubmed
Clinical Assessment of
Urinary Tract Damage during Sustained - Release
Estrogen Supplementation in
Mice . -
pubmed
The goal of this study was to develop a clinical scoring system and identify biomarkers of
occult urinary tract lesions prior to the development of
systemic illness in
mice . -
pubmed
All
mice with
urolithiasis had
crystalluria , and 5 of the 6
mice with
pyelonephritis or
hydroureter had dilute urine ( that is , specific gravity less than 1.030 ) . -
pubmed
A total clinical score of 3.5 ( maximum , 24 ) identified
estradiol - supplemented
mice with 83 % specificity and 50 % sensitivity , but no single clinical parameter , biomarker , or the total clinical score accurately predicted occult
urinary tract lesions . -
pubmed
To further characterize the pathogenic role of
PCs , the expression levels of 17 selected miRs known to be involved in the development of
CLL /
SLL were compared in the
PCs and the intervening small cell areas in lymph nodes of 15
patients with
CLL /
SLL . -
pubmed
Combined administration of a sedative dose
sevoflurane and 60 %
oxygen reduces inflammatory responses to
sepsis in animals and in
human PMBCs . -
pubmed
More than 50 allergens were associated with
SCs including
quaternium-15 ( 11.2 % ) ,
cocamidopropyl betaine ( 9.5 % ) ,
methylchloroisothiazolinone /
methylisothiazolinone ( 8.4 % ) ,
coconut diethanolamide ( 7.9 % ) , fragrance mix I ( 7.7 % ) ,
Myroxylon pereirae ( 5.9 % ) ,
4 - chloro-3,5 - xylenol ( 5.8 % ) ,
amidoamine ( 5.5 % ) , and
formaldehyde ( 4.4 % ) . -
pubmed
Methods : A hospital - based , cross - sectional study was carried out on 30 clinically diagnosed cases of
infantile hemangioma and 30
controls presenting with other disorders . -
pubmed
Streptococcus pyogenes is an exclusively
human pathogen that can provoke mild
skin and throat infections but can also cause fatal
septicemia . -
pubmed
Hand , Foot and Mouth Disease and
Echovirus 3 : A Comment to Hogsberg & amp ; Bygum . -
pubmed
One hundred three older
individuals with varying
cognitive impairment levels were included and underwent neuroimaging . -
pubmed
They are taken up by
human lung adenocarcinoma A549 cells very quickly and specifically target mitochondria . -
pubmed
Seventy - two
patients with
head trauma were randomly allocated to equal intervention and control groups . -
pubmed
Methodology : Sixty
individuals were included in this study :
OSCC ( 20 ) ,
PMD ( 20 ) and Control ( 20 ) . -
pubmed
The present study investigated both autophagy and apoptosis in
ICR mice and
Human hepatocellular carcinoma cells (
HepG2 ) , and then explored the interactive mechanism between these two distinct cell
death modalities in
HepG2 cells . -
pubmed
Mice liver injuries seen by
hematoxylin and
eosin ( HE ) staining indicated the
hepatotoxic effects of nanosilica . -
pubmed
To disambiguate the role of immunoglobulins in
MI , we characterized the development of
ischemic heart failure in
agammaglobulinemic mice ( AID-/-muS-/- ) . -
pubmed
These differences remained significant even after
animals with matched
infarct sizes were compared . -
pubmed
METHOD : This retrospective study included 114
patients who underwent angiography for upper or lower
GI bleeding . -
pubmed
Patients with a history of
malignancy were more likely to rebleed ( OR 4.4 , 95%CI 1.06 - 18.36 , p=0.04 ) . -
pubmed
CONCLUSIONS : This paper identified important clinical predictors of arterial extravasation , rebleed and 30 - day mortality in
GI bleedings , which will assist in
patient selection and help to improve the overall angiographic management of
GI bleeding . -
pubmed
Results revealed that
patients with
mTBI had significantly reduced cortical thickness in the left entorhinal cortex while increased cortical thickness in the left precuneus cortex and right lateral occipital cortex , compared with healthy controls . -
pubmed
Behavior problems in
children with
epilepsy and
attention - deficit hyperactivity disorder in Central China . -
pubmed
In this study , we aimed to evaluate the prevalence of
attention - deficit hyperactivity disorder (
ADHD ) in
children with
epilepsy in Central China and compare the behavioral problems in
children with
epilepsy combined with and without
ADHD . -
pubmed
Children with
epilepsy aged between 6 and 16 years were recruited for this study . -
pubmed
Among 206
children diagnosed as having
epilepsy , 51 had
ADHD symptoms . -
pubmed
Children with
epilepsy and
ADHD had significantly higher scores on attention problems , rule - breaking behavior , and
aggressive behavior subscales ( P & lt ; 0.01 ) . -
pubmed
Children with
epilepsy and
ADHD showed more behavior problems such as
attention - deficit , delinquent , and
aggressive behaviors compared with children with
epilepsy only . -
pubmed
Illicit drug use and
acute kidney injury in
patients admitted to hospital with
rhabdomyolysis . -
pubmed
Effect of
Gmelina arborea on learning and memory in
amnesia - induced and non -
amnesia groups of albino
Wistar rats . -
pubmed
The crude extracts of the
Gmelina arborea plant are reported to possess
wound - healing , anti - diarrheal , anti - oxidant , anti - diabetic , and anti -
ulcer property . -
pubmed
arborea on
learning and memory in albino
Wistar rats . -
pubmed
arborea on learning and memory in both
amnesia - induced and non -
amnesia groups of
rats . -
pubmed
Developmental delay ,
hypotonia ,
hypomyelination , and thyroid hormone profile help to diagnose
patients . -
pubmed
Maternal and neonatal outcomes following a
diabetic pregnancy within the context of
HIV . -
pubmed
METHODS : Sample consisted of 40 normotensive
men ( aged 31 - 59 years ) with no history of
CVD of currently taking medication . -
pubmed
Two
patients developed
cerebrovascular accidents . -
pubmed
Spinal cord injury occurred in 2
patients . -
pubmed
Postoperative renal failure , postoperative extracorporeal membrane oxygenation support , and
pneumonia were reported in 3 , 1 , and 6
patients , respectively . -
pubmed
Stent - related
aortic complications were observed in 5
patients ( 6.8 % ) . -
pubmed
The 17 - year old
patient suffers from
multiorgan failure . -
pubmed
Targeted
tumour theranostics in
mice via
carbon quantum dots structurally mimicking large
amino acids . -
pubmed
Effects of
nebivolol versus other antihypertensive drugs on the
endothelial dysfunction in
patients with essential
hypertension . -
pubmed
Patients with ventricular assist devices ( VADs ) and extracorporeal membrane oxygenation ( ECMO ) suffer from an increased risk for
thromboembolic events as well as for
hemorrhages . -
pubmed
xSafety , Tolerability , and Pharmacokinetics of Crenezumab in
Patients with Mild - To - Moderate
Alzheimer ' s Disease Treated with Escalating Doses for up to 133 Weeks . -
pubmed
METHODS : In this multicenter , double - blind study ,
participants ( aged 50 - 90 years ) with mild - to - moderate
Alzheimer ' s disease (
AD ) and amyloid - positive PET scan were randomized to receive crenezumab 30 or 45 mg / kg ( Cohort 1 , n = 21 ) , 60 mg / kg ( Cohort 2 , n = 21 ) , or 120 mg / kg ( Cohort 3 , n = 19 ) or corresponding placebo ( n = 14 ) intravenously q4wfor 13 weeks . -
pubmed
Since its introduction to North America in the early 1900s ,
white pine blister rust (
WPBR ) caused by the fungal pathogen
Cronartium ribicola has resulted in substantial economic losses and ecological damage to native North American five - needle pine species . -
pubmed
Open - pollinated seed families were evaluated for host reaction following controlled
infection using
C. - pubmed
To the best of our knowledge , this is the first verification of
AS in EEG signals and in the
human brain . -
pubmed
Based on this , we present a new in vitro culture protocol to obtain
polyploid organisms using
zeatin riboside ( ZR ) and
eggplant as a model organism . -
pubmed
The regeneration of whole plants from the appropriate tissues using ZR allowed developing
polyploid individuals in
eggplant , a crop that tends to be recalcitrant to in vitro organogenesis . -
pubmed
It has been linked to the risk of development of
spondyloarthritis , and it associates with the immune infiltration of
tumours and strongly predicts the overall survival for
patients receiving check - point inhibitor therapy . -
pubmed
The pooled prevalence of
Plasmodium falciparum and
Plasmodium vivax , and mixed
infections were 12 , 30 , and 6 % , respectively . -
pubmed
BACKGROUND : The durability of improved
xerostomia with intensity - modulated radiotherapy ( IMRT ) in
patients with early stage
nasopharyngeal carcinoma (
NPC ) is uncertain . -
pubmed
METHODS : Parent study
participants ( IMRT , n = 28 ; 2DRT , n = 28 ) who were free of
second malignancy or recurrence were eligible . -
pubmed
Long - term
patient - reported outcomes were assessed by the six - item
xerostomia ( XQ ) and two European Organisation for Research and Treatment of
Cancer ( EORTC ) questionnaires ( QLQ - C30 , QLQ - H&N35 ) . -
pubmed
Patients in the IMRT arm reported lower mean scores for the "
dry mouth " domain of EORTC QLQ - H&N35 ( p = 0.02 ) and showed trends toward better 15 - year OS ( 81.5 % vs. 53.8 % , p = 0.06 ) , LRFS ( 70.6 % vs. 53.8 % , p = 0.38 ) , and DRFS ( 81.5 % vs. 53.8 % , p = 0.07 ) . -
pubmed
CONCLUSIONS : The parotid - sparing effect of IMRT in NPC treatment is durable , with significantly less physician- and
patient - scored
xerostomia at 15 years . -
pubmed
CONCLUSIONS : Since its clinical presentation is variable , clinical suspicion is important in the presence of a
skin lesion of torpid evolution taking into account the
patient 's oncological history . -
pubmed
Recent developments in
bovine leukemia research and regulatory programs . -
pubmed
[ Development of
strains of molossinus
mice and their application -- significance of their species characteristics ] . -
pubmed
28
patients with
spondylolisthesis who underwent anterior interbody fusion at the Orthopaedic Department of the University of Basle between 1968 and 1976 , have been follow - up . -
pubmed
A
patient with a large , long - standing
posterior fossa arachnoid cyst was evaluated . -
pubmed
Studies on the susceptibility of the laboratory animals , kids , and
lambs to experimental
infection with
Schistosoma nasale Rao 1933 . -
pubmed
Intravenous
miconazole monotherapy for 3 weeks cured a 67 - year - old
patient with a 2 - year history of
esophageal candidiasis . -
pubmed
Some circulatory and respiratory effects of
morphine in
patients without pre - existing
cardiac disease . -
pubmed
morphine ( 10 mg/70 kg
body weight ) were studied in 10
adults with unimpaired circulatory function . -
pubmed
Cell - mediated antitumor immunity in
breast cancer patients evaluated by antigen - induced leukocyte adherence inhibition in test tubes . -
pubmed
Tumor antigen - induced inhibition of leukocyte adherence was adapted and modified for use in glass test tubes for the study of cell - mediated antitumor immunity to
human adenocarcinoma of the breast . -
pubmed
Peripheral blood leukocytes from 40 to 47
patients with proven
breast cancer responded to an antigenic extract of
breast cancer with significant leukocyte adherence inhibition , whereas only 2 of 32 controls showed a response . -
pubmed
Further , 7
patients with histologically proven benign
breast disease did not react to the
breast adenocarcinoma extract , indicating that only
breast cancer patients have leukocytes sensitized to the
breast cancer antigen . -
pubmed
The cell - mediated antitumor response of the
breast cancer patient was dependent on the stage of the
cancer , and
patients with disseminated
cancer had decreased responsiveness . -
pubmed
In P(A ) H block group ( 23 cases ) , the permanent pacemaker implantation was not needed except for one
patient with persistent
heart failure due to marked
bradycardia . -
pubmed
BACKGROUND AND METHODS : We performed a multicenter , randomized , unblinded clinical trial ( the
Foscarnet -
Ganciclovir Cytomegalovirus
Retinitis Trial ) designed to compare
ganciclovir with
foscarnet in the treatment of
cytomegalovirus retinitis in
patients with the
acquired immunodeficiency syndrome (
AIDS ) . -
pubmed
The
patients were followed for the progression of
retinitis ,
visual loss , and death . -
pubmed
CONCLUSIONS : These results suggest that for
patients with
AIDS , and
cytomegalovirus retinitis , treatment with
foscarnet offers a survival advantage over treatment with
ganciclovir , although the patients may not tolerate
foscarnet as well as
ganciclovir . -
pubmed
Deletion of chromosome 11p13 - 11p15.5 sequences in invasive
human ovarian cancer is a subclonal progression factor . -
pubmed
In
human ovarian cancer , multiple specific chromosomal deletions can be found by cytogenetic analysis or molecular techniques such as restriction fragment length polymorphism probing . -
pubmed
Expression of a transfected H-2Kb gene in
B16 cells correlates with suppression of
liver metastases in
triple immunodeficient mice . -
pubmed
injected
B16 - F1 and
B16 - F10 murine melanoma cells to colonize not only the lungs but also the liver of TD
mice . -
pubmed
Bacterial skin infection with
Staphylococcus aureus and sometimes beta - haemolytic streptococci is common and is best treated with oral antibiotics . -
pubmed
A multimodality approach of moderate - dose to high - dose preoperative radiation therapy , surgical resection , and intraoperative electron beam radiation therapy ( IORT ) has been used for
patients with locally recurrent rectal or rectosigmoid
carcinoma . -
pubmed
The 5 - year actuarial local control and
disease - free survival for 30
patients undergoing this treatment program were 26 % and 19 % , respectively . -
pubmed
The determinant local control and
disease - free survival for 13
patients undergoing complete resection were 62 % and 54 % , respectively , whereas for 17
patients undergoing partial resection these figures were 18 % and 6 % , respectively . -
pubmed
For the 30
patients undergoing external beam irradiation , resection , and IORT , the most significant toxicities were soft tissue or
sacral injury and
pelvic neuropathy . -
pubmed
Rhodococcus equi is an uncommon pathogen in
humans that has occasionally been reported to cause
infection in individuals with
impaired cellular immunity . -
pubmed
We summarize 30 previously published reports of
human infection with R. equi and describe one additional case in a patient with
AIDS . -
pubmed
Seventy - seven percent of all patients had
pneumonia due to
R. - pubmed
When
HIV - infected patients were compared with those not infected with the virus , symptoms , age , and frequency of
pneumonia were similar . -
pubmed
Individuals with
HIV infection also had a higher incidence of simultaneous
secondary infections and higher mortality than non -
HIV - infected patients ( 54.5 % vs. 20 % ) . -
pubmed
[ Effectiveness of therapeutic and preventive procedures in
children with
chronic digestive system diseases in a day - care hospital ] . -
pubmed
The author characterizes in detail 4340
patients with
diffuse renal lesions (
chronic glomerulonephritis ,
renal amyloidosis ,
lupoid nephritis ,
diabetic glomerulosclerosis and
nephrosclerosis ) coupled with different diseases of the urinary organs including
urolithiasis , cancerous and tuberculous processes ,
purulent diseases of the kidneys and
prostatic lesions . -
pubmed
Stage III
chronic renal failure (
CRF ) was revealed in 2073 ( 57.1 % ) out of the 4340
patients . -
pubmed
The shortest times of
CRF onset , the highest frequency of stage III
CRF and the least lifespan were noted in
patients with double association , particularly in those suffering from associated
chronic glomerulonephritis with
renal amyloidosis and
urinary bladder cancer in the stage of compression with
tumor of the intramural parts of the ureters , namely they were 0.6 + /- 0.1 , 100 % and 1.0 + /- 0.1 yr . -
pubmed
The author holds that the main reason for such an abrupt
CRF onset in
patients with concomitant
renal lesions of any type lies in simultaneous combined influence on the kidneys of absolutely different diseases bearing in mind their etiology and pathogenesis . -
pubmed
We examined
ozone - induced airway inflammatory responses in inbred
mice , and progeny of crosses between them , to investigate
genetic susceptibility to
ozone . -
pubmed
Two
patients with resectable secondaries in the liver developed needle track
recurrence following intraoperative " Trucut"-needle biopsy and percutaneous thin needle aspiration cytology , respectively . -
pubmed
Patients with stable
chronic renal failure maintained on protein restriction were given
sodium bicarbonate supplementation for 8 weeks . -
pubmed
Some
opisthorchiasis foci are found in the Biryusa basin , local cases of
human invasion are registered in regions on the Taseyeva river , down the Angara , and in one of the Yenisei regions where invasion foci of low intensity are supposed to exist . -
pubmed
Social and cultural habits of
human populations affect the biological evolution of the agents of
infectious diseases . -
pubmed
Burn patients often exhibit prolonged cell - mediated immune suppression . -
pubmed
Triplicate samples of 10 % dilutions of
burn serum from nine
burn patients ( three with greater than 60 %
burn ) were analyzed for their ability to suppress mitogen - induced lymphocyte blastogenesis . -
pubmed
The serum of
patients with greater than 60 %
burn was significantly more suppressive ( as measured by depressed
tritiated thymidine incorporation by
cultured lymphocytes ) than that taken from
patients with smaller
burns . -
pubmed
Altered function of synovial fluid granulocytes in
patients with
acute inflammatory arthritis : evidence for activation of neutrophils and its mediation by a factor present in synovial fluid . -
pubmed
Survival of the islet grafts was also independent of the duration of
diabetes in the BB / W
rats at the time of transplantation . -
pubmed
Similar changes occur during normal development , but the ( n-3 ) to ( n-6 ) ratio of
PUFA in these
phosphoglycerides of
Down ' s syndrome at the fifth month of gestation resembled that of normal
human cerebral grey matter at term . -
pubmed
Comparison of effects of three anesthetic agents on induction of
ventricular tachycardia in a
canine model of
myocardial infarction . -
pubmed
The effects of three anesthetic agents on the inducibility of
ventricular tachycardia by programmed stimulation were investigated in
dogs with a surgically induced
left ventricular infarct . -
pubmed
Endocardial catheter electrodes were placed at the right ventricular apex under general anesthesia at least 2 weeks after
infarction , and the
dogs were allowed to recover for 24 hours before undergoing programmed stimulation in the conscious state on two occasions 2 hours apart . -
pubmed
In 15
animals ,
ventricular tachycardia was inducible on both occasions with 3.4 + /- 0.4 ( mean + /- SEM ; range , 1 - 5 ) extrastimuli . -
pubmed
The ability to induce
ventricular tachycardia was abolished in five of 10
animals ( p less than 0.05 ) . -
pubmed
In the
animals that remained inducible , the cycle length of
tachycardia increased from 153 + /- 10 to 168 + /- 10 msec ( p = 0.015 ) , while the number of extrastimuli required was unaltered . -
pubmed
Ventricular tachycardia remained inducible in only six of 10
dogs ( p less than 0.05 ) with no change in cycle length or the number of extrastimuli required . -
pubmed
Ventricular fibrillation was inducible in an additional three
dogs with a number of extrastimuli similar to that required to induce
ventricular tachycardia before anesthesia. -
pubmed
Testing ciliary activity in
patients with chronic and recurrent
infections of the upper airways : experiences in 68 cases . -
pubmed
Therefore , biopsy specimens of the nasal mucosa were investigated by means of phase contrast microscopy in 68
patients with chronic and recurrent
infections of the upper airways . -
pubmed
Ultrastructurally , a characteristic pattern of defective dynein arms as observed in
primary ciliary dyskinesia , was evident in only 3 out of these 19
patients . -
pubmed
Over a 9 - month period 228
men were admitted for acute
urinary retention to six different casualty wards in the Copenhagen area . -
pubmed
The etiology of the acute retention was
infravesical obstruction in 90 % of the
patients , and 85 % required subsequent surgical treatment . -
pubmed
In several previous
rodent studies , the
toxicity and tissue concentrations of
iodipamide ethyl ester (
IDE ) particles have been evaluated . -
pubmed
SP recorded from the genital skin is a useful method of evaluating the
autonomic - sympathetic dysfunction causing
impotence , especially in
patients who may have
autonomic disorders either located in lumbosacral spinal cord and its efferents , or generalized
autonomic - peripheral dysfunction . -
pubmed
A comparative study of peritoneal fluid concentrations of
oestradiol-17 beta ,
progesterone , and
testosterone in controls and in
patients with
endometriosis . -
pubmed
Forty six
patients ( mean age , 30.1 + /- 6 years ) with
pelvic endometriosis and 32 control
patients ( mean age , 32.2 + 3.8 years ) without
endometriosis were studied . -
pubmed
The new long - acting
ergoline derivative
cabergoline was given orally in a single dose of 300 micrograms to 15
hyperprolactinemic patients ( including 4
acromegalic patients , 2 of whom were
dopamine responsive ) . -
pubmed
The only symptomatic side - effect was
orthostatic hypotension after
cabergoline in an elderly
woman . -
pubmed
These data indicate that
cabergoline has potent and prolonged dopaminergic activity and may prove suitable for once weekly treatment of
hyperprolactinemic patients . -
pubmed
The incidence of acute and
chronic liver damage and its relation to
hepatitis B virus ( HBV ) infection was evaluated in 164 consecutive
children with
acute leukemia seen in ten Italian hemato - pediatric units . -
pubmed
Thirteen out of 164
children ( 7.9 % ) had acute
hepatitis (
AH ) during treatment , while 8/90 ( 8.8 % ) showed an acute exacerbation of
liver damage within 6 months after therapy withdrawal . -
pubmed
Seven of the 13
children with
AH while on therapy were
HBsAg positive . -
pubmed
Five of eight
children who developed
AH after completion of treatment were
HBsAg positive . -
pubmed
The outcome of these
liver diseases after treatment withdrawal did not differ significantly in relation to
HBV serology , suggesting that viral rather than toxic agents were responsible for
liver damage also in most
HBsAg - negative patients . -
pubmed
The high incidence of chronic
HBV infection in children with
leukemia found in this multicentric study could suggest a need for active immunization with
HBV vaccine , but the efficacy of such approach in this clinical setting is still to be validated . -
pubmed
Sonography as a substitute for excretory urography in
children with
urinary tract infection . -
pubmed
The possibility was explored of substituting renal sonography for excretory urography in
children with
urinary tract infection . -
pubmed
A comparative study on the effects of
ascorbic acid deficiency and supplementation on endurance and mitochondrial oxidative capacities in various tissues of the
guinea pig . -
pubmed
The aim of this study was to ascertain the effects of
ascorbic acid deficiency and supplementation on endurance and mitochondrial oxidative capacities in various tissues of
guinea pigs . -
pubmed
Experience with the management of 106 consecutive
patients found to have a retroperitoneal
haematoma (
RH ) at laparotomy for
penetrating trauma over a 2 - year period is reviewed . -
pubmed
Fourteen
patients died ( 63.8 per cent ) representing 70 per cent of all
deaths in the series . -
pubmed
Type III
RH was found in 11
patients and was due to
iliac vessel injuries . -
pubmed
Pineal denervation by cervical sympathetic ganglionectomy suppresses the role of photoperiod on pregnancy or pseudopregnancy ,
body weight and moulting periods in the
mink (
Mustela vison ) . -
pubmed
Fifty - four
patients with advanced upper
gastrointestinal cancer were assessed for their nutritional status prior to any form of therapy . -
pubmed
Identity of a newly isolated
human polyomavirus from a
patient with
progressive multifocal leucoencephalopathy . -
pubmed
Isolation of a
strain of polyomavirus , designated COL , from the brain of a
patient with
progressive multifocal leucoencephalopathy is described . -
pubmed
The COL
strain is antigenically similar to
JC polyomavirus , previously isolated from a brain affected by
progressive multifocal leucoencephalopathy and is unrelated to BK , another
human polyomavirus isolated from urine . -
pubmed
Some effects of
protein deficiency in young growing
pigs . -
pubmed
Aggregation of washed platelets from
stroke - prone spontaneously
hypertensive rats(SHRSP ) was markedly reduced with the development of
hypertension in comparison with age - matched normotensive
Wistar Kyoto rats(WKY ) ( Tomita et al . -
pubmed
The experience with 43 consecutive chest wall resections in
patients with
breast cancer affords the opportunity to define indications and contraindications for such palliative procedures . -
pubmed
Three
patients who underwent resection for local
recurrence have survived 40 months or more free from disease . -
pubmed
In the proper setting , chest wall resection is an important part of the armamentarium for palliation of the
patient with
breast cancer . -
pubmed
Both synthetic and natural
estrogens have been studied for their ability to induce
renal carcinomas in castrated
male hamsters after 9.0 months of treatment . -
pubmed
tumor foci ] in these
animals . -
pubmed
However ,
alpha - dienestrol and
DES 3,4 - oxide showed an 86 to 88 % incidence of
renal tumors in
hamsters ( approximately 10.8 + /- 3 ) . -
pubmed
Moreover , the poor carcinogenic activity of
ethinyl estradiol in this system , despite strong estrogenicity , suggests that estronic activity alone may not be sufficient to effect renal
tumorigenesis in the
hamster . -
pubmed
Treatment of a 60 - year - old
woman with
scleromyxoedema with
8 - methoxypsoralen and UV - A radiation ( PUVA ) resulted in significant clinical and histological improvement but no change in circulating paraprotein . -
pubmed
In a prospective study of 336 consecutive
patients with long - term
pleural effusions , 32 cases of
malignant mesothelioma were found . -
pubmed
The effect of sublingual or intracoronary
nitroglycerin (
NTG ) on luminal caliber in normal and diseased portions of epicardial coronary arteries was determined in 85 lesions from 57 typical
patients with
ischemic heart disease . -
pubmed
Edematous necrosis in
thiamine - deficient
encephalopathy of the
mouse . -
pubmed
Acute
encephalopathy was produced in the adult male Swiss
mouse by
pyrithiamine injection in conjunction with a
thiamine - deficient diet . -
pubmed
These lesions of
thiamine - treated
encephalopathy of the
mouse closely resembled the non - hemorrhagic lesions of
human Wernicke encephalopathy . -
pubmed
Mice which were concomitantly - induced with
hyperglycemia and
encephalopathy showed no significant differences in clinical and morphologic manifestations from the
encephalopathic mice with normal blood
sugar levels . -
pubmed
The
patients who survive gallbladder
carcinomas more than five years are usually those in whom the
carcinoma was first diagnosed at microscopic examination of gallbladders removed for presumed benign disease . -
pubmed
The prognosis was far better in the 11
patients in which the
cancer was confined to the mucosa or submucosa . -
pubmed
Five of the 11
patients died because of
recurrence . -
pubmed
Radical cholecystectomy including a wedge resection of liver tissue and dissection of the regional lymph nodes is recommended in all
patients with inapparent
gallbladder carcinomas . -
pubmed
Signs of
kidney dysfunction detectable in urinary protein excretion were searched for in a group of 86
silica - exposed
workers who were compared to 86 control subjects matched for age , smoking status and
body mass index . -
pubmed
Only a few people know that the native Swiss and student of Pasteur and Roux spent nearly 50 years of his life in Vietnam , where he became director of the Pasteur institutes and earned merits by his engagement for the control of
communicable diseases in
humans and animals . -
pubmed
Ondansetron reduces the incidence and severity of poststrabismus repair
vomiting in
children . -
pubmed
The number of
children vomiting prior to discharge and within 24 h of surgery was significantly reduced in Group 3 compared with Group 1 ( P & lt ; 0.003 and P & lt ; 0.015 , respectively ) . -
pubmed
The number of
vomiting episodes per
patient in Groups 1 , 2 , and 3 was 1.1 , 0.5 , and 0.1 prior to discharge , and 4.5 , 2.6 , and 1.2 during the 24 h after surgery ( P & lt ; 0.0005 and P & lt ; 0.004 , respectively ) . -
pubmed
OBJECTIVE : This study was done ( 1 ) to determine whether congenital indirect
inguinal hernias in male
pigs could be repaired by placing a
polypropylene mesh prosthesis over the defect intra - abdominally , ( 2 ) to measure the incidence of adhesions between intra - abdominal viscera and the prosthesis with and without the adhesion barrier oxidized regenerated cellulose , ( 3 ) to determine the incidence of other complications , and ( 4 ) to assess the effect on fertility . -
pubmed
METHODS : In male
pigs ,
polypropylene mesh alone or
polypropylene mesh plus the adhesion barrier oxidized regenerated cellulose ( composite prosthesis ) was fixed to the peritoneum surrounding the
hernia defect . -
pubmed
Human gene therapy is one of the promising approaches in treatment of
genetic diseases and rapid development of molecular genetic methods is bringing this therapy in life . -
pubmed
Metabolism of
antipyrine in vivo in two
rat models of
liver cirrhosis . -
pubmed
We investigated to what extent
antipyrine clearance and metabolite formation are impaired in two models of
liver cirrhosis in the
rat , namely micronodular
cirrhosis induced by chronic exposure to
phenobarbital /
CCl4 and
biliary cirrhosis induced by bile duct ligation . -
pubmed
The microsomal
cholesterol content was increased by 16 % and 90 % in
CCl4 and bile duct - ligated
cirrhotic rats ( P & lt ; 0.001 ) , respectively . -
pubmed
Unilateral renal artery revascularization can salvage renal function and terminate dialysis in selected
patients with
uremia . -
pubmed
Revascularization of renal arteries to salvage glomerular function in
patients with
chronic renal failure is performed infrequently . -
pubmed
However , during the past 12 months we have encountered three
patients over 60 years of age known to have
chronic renal failure who were on dialysis for 2 weeks , 3 weeks , and 2 months , respectively . -
pubmed
All three
patients were
hypertensive , requiring between four and five antihypertensive medications . -
pubmed
One
patient was ventilator dependent in intractable
cardiac failure with pulmonary artery
systolic pressures ranging from 60 to 70 mm Hg . -
pubmed
Standard biplanar arteriography revealed occlusion of the left renal artery with distal reconstitution in two
patients and a 99 %
stenosis of the right renal artery in the remaining
patient . -
pubmed
[ Immediate effect of hemodialysis with
cuprophane membrane and
acetate containing dialysis fluid on respiratory function in
patients with
chronic renal failure ] . -
pubmed
In 20
patients with
chronic renal failure on a hemodialysis ( HD ) programme with a
cuprophane membrane and
acetate - containing dialysis fluid , gasometric parameters , ventilation disturbances and peripheral blood leucocyte count were determined . -
pubmed
We report here on a female Greek
patient with homozygous
beta - thalassemia but normal growth and development , excellent exercise tolerance , and no need of blood transfusions . -
pubmed
34
patients with metastatic
colorectal cancer were treated with the
ether lipid
miltefosine (
hexadecylphosphocholine ) . -
pubmed
Nausea and
vomiting were the most frequent side - effects occurring in all but 3
patients ,
nephrotoxicity was observed in 11
patients . -
pubmed
Leucocytosis was observed in 24 and
thrombocytosis in 17
patients . -
pubmed
1
patient obtained a partial response of
liver metastases for a duration of 8 months . -
pubmed
Three
patients with histologically confirmed ascarid
granuloma who presented clinically with abdominal masses simulating
abdominal tuberculosis or
lymphoma are described . -
pubmed
Since
NaHCO3 is a treatment option in
patients with severe
metabolic acidosis , the purpose of this study was to examine the acute effect of the administration of
NaHCO3 on back - titration of non -
bicarbonate buffers in
metabolic acidosis . -
pubmed
In group A , 22
patients ( 24.2 % ) resulted as suffering from
prostatic carcinoma , 4 ( 4.3 % ) resulted as suffering from
prostatic phlogosis , and 65 ( 71.4 % ) resulted as suffering from
BPH . -
pubmed
The
rats were water loaded with 5 % of their
body weight by gavage twice , with the second gavage one hour after the first . -
pubmed
In this study we have evaluated the fluence rate effect with a second - generation photosensitizer ,
tetra ( m - hydroxyphenyl ) chlorin (
mTHPC ) using a
7,12 - dimethylbenz ( a ) anthracene induced early
squamous cell carcinoma of the
Syrian hamster cheek pouch as a
tumor model . -
pubmed
PURPOSE :
Patients with
aneurysmal disease involving both the descending thoracic and abdominal aorta have historically required simultaneous or sequential conventional operations , but the morbidity rate is high with either approach in these
patients , who often exhibit coexisting
cardiopulmonary disease . -
pubmed
Transluminally placed endovascular grafts have recently been developed for repair of
aortic aneurysms , and we have implemented these techniques to eliminate the need for a thoracotomy in
patients with multilevel
aortic disease . -
pubmed
No
patients required further surgical intervention to treat their
aortic disease . -
pubmed
Seventeen
patients ( 94 % ) are currently well 14 + /- 8 months after surgery ( range , 3 to 29 months ) with completely excluded
thoracic aortic disease , no stent migration , and no change in stent configuration documented by serial radiologic examinations . -
pubmed
CONCLUSIONS : Simultaneous abdominal aortic replacement and deployment of a thoracic stent - graft can safely exclude multilevel
aortic aneurysmal disease and may be a valuable treatment option for these otherwise high - risk
patients . -
pubmed
We now study the correlation between the plasma antioxidant capacity and tissue oxidative damage , after acute ( one and two doses ) and prolonged ( eight doses )
ALA treatment of
rats ( one dose of
ALA = 40 mg / kg
body weight ) . -
pubmed
Expression of a pim-2 transgene in lymphoid cells predisposed
mice to
T - cell lymphomas like those promoted by pim-1 transgenes . -
pubmed
Moreover , strong collaboration with an E mu - myc transgene was manifested as
pre - B cell leukemia in neonate bi - transgenic
animals . -
pubmed
These methods were used to ascertain the
L - DOPA /
L - tyrosine ratio in plasma of
patients with
melanoma . -
pubmed
For 29
patients diagnosed as having
melanoma without
metastasis , the
L - DOPA /
L - tyrosine ( 11.96 x 10(-5 ) + /- 2.69 x 10(-5 ) ) level was not significantly different from that of 35 normal controls ( 11.20 x 10(-5 ) + /- 2.92 x 10(-5 ) ) . -
pubmed
However , this level was significantly increased ( p & lt ; 0.05 ) in the plasma of 17
patients with developing
metastasis ( 21.02 x 10(-5 ) + /- 4.68 x 10(-5 ) ) . -
pubmed
A
hypertensive crisis was induced by
metoclopramide , a widely used anti - emetic , in a pregnant normotensive
woman . -
pubmed
Lameness in the dairy
cow :
pain and welfare . -
pubmed
The
fatty acid profile of subcutaneous fat and blood plasma in
pruritic dogs and
dogs without skin problems . -
pubmed
Group 2 was comprised of
dogs with
pruritus and compatible clinical signs of
atopy . -
pubmed
In subcutaneous fat , the concentration of
adrenic acid (
22:4n-6 ) was lower in the group of
pruritic dogs compared to
dogs with healthy skin . -
pubmed
The amount of
dihomogammalinolenic acid (
20:3n-6 ;
DGLA ) in plasma lipids from
pruritic dogs was higher than in
dogs without
skin problems . -
pubmed
Methods of identifying
patients at high risk of subsequent
arrhythmic death after
myocardial infarction . -
pubmed
Cerebral magnetic resonance imaging in
patients with
chronic liver disease . -
pubmed
Future studies employing magnetic resonance imaging techniques to obtain information on cerebral function or combined with magnetic resonance spectroscopy to obtain localized biochemical information might further our understanding of the pathogenesis of
hepatic encephalopathy in cirrhotic
patients . -
pubmed
OBJECTIVE : To enhance awareness of issues affecting
patients with
chronic renal failure and to provide guidance for primary care practitioners managing such patients . -
pubmed
The benefits of lipid lowering are suggested by randomized trials among
patients without
renal disease . -
pubmed
MAIN MESSAGE : Progression of
renal failure , particularly in
patients with
proteinuria , can be slowed by lowering blood pressure . -
pubmed
CONCLUSIONS : Care of
patients with
progressive renal failure is complex and requires attention to detail . -
pubmed
OBJECTIVES :
Patients with
Parkinson ' s disease characteristically have difficulty in sustaining repetitive motor actions . -
pubmed
METHODS : Ocular pursuit in seven
patients with moderate to severe
bradykinesia predominant
Parkinson ' s disease was compared with seven age matched controls . -
pubmed
The distinctive findings in
patients with
Parkinson ' s disease were a reduction in response magnitude compared with controls and a progressive decline of response with stimulus repetition . -
pubmed
The clinical significance of
hepatitis G virus ( HGV ) infection was studied in 35
patients with various
liver diseases of unknown etiology . -
pubmed
HGV RNA was detected in 3 of 5 cases of acute
hepatitis , 3 of 23 cases of
chronic liver diseases , and 1 of 7 cases of
hepatocellular carcinoma . -
pubmed
The
HGV positive rate was high in patients with
acute hepatitis suggesting that
HGV might cause
acute liver injury . -
pubmed
Therefore ,
HGV was thought to be an important etiological agent for
liver injury . -
pubmed
Acute
GVHD of grades II - IV developed in six
patients transplanted with PBPC and three
patients transplanted with BM . -
pubmed
The numbers of
patients with chronic
GVHD were 15 and 8 , respectively . -
pubmed
A fatal case of
methane and
cyanide poisoning among a group of deep
sea trawler men is described . -
pubmed
We have demonstrated previously that the preferential adhesion of
prostate cancer cells to
human bone marrow endothelial ( HBME ) cells may contribute to their preferential
metastasis to bone . -
pubmed
Two aerobic bacterial
strains , a
chlorophenol - degrading bacterium characterized in this work as a
Ralstonia sp . - pubmed
Preoperative risk assessment for gastrostomy tube placement in
head and neck cancer patients . -
pubmed
METHODS : We performed a retrospective chart review of 142
patients who underwent extirpative surgery for
head and neck cancer . -
pubmed
Candida albicans , as an opportunistic pathogen , causes therapeutic problems in immunocompetent individuals and frequently it initiates severe
infections in immunocompromised hosts . -
pubmed
albicans
infections in inbred
ICR mice which have normal complement production . -
pubmed
infections in DBA/2
mice which are
deficient in C5 complement component . -
pubmed
The preparation enhanced delayed type
hypersensitivity to the
yeast cells in both
mouse strains . -
pubmed
albicans
infection in
ICR mice treated with cobra venom and
cyclophosphamide . -
pubmed
All
patients received standard anti - microbials and
graft - versus host disease (
GVHD ) prophylaxis including
cyclosporin A and a short course of
methotrexate . -
pubmed
Early
portal vein thrombosis is a rare but severe posttransplant complication that may lead to graft and/or
patient loss . -
pubmed
PATIENTS : The study was based on
patients treated for
skeletal metastases ,
myeloma or
lymphoma between 1986 and 1998 at the Oncology Service , Department of Orthopedics , Karolinska Hospital and on
patients diagnosed with symptomatic skeletal
metastases 1989 - 1994 in the Stockholm Region . -
pubmed
EPIDEMIOLOGY : 641
breast cancer patients were diagnosed with symptomatic skeletal
metastases 1989 - 1994 . -
pubmed
Multivariate analysis based on 619
patients showed that complete pathologic
fracture and soft tissue
metastases were negative prognostic variables for 1 - year survival after operation . -
pubmed
DIAGNOSIS : Fine Needle Aspiration Biopsy ( FNAB ) was assessed in 110
patients for diagnostic accuracy and to which extent information about primary site of the metastatic
carcinoma could be gained . -
pubmed
There were 80
patients with metastatic
carcinoma , 14 with
lymphoma , and 16 with
myeloma . -
pubmed
Hence , 27 of 30
myeloma or
lymphomas were diagnosed by FNAB and in half of the
patients with metastatic
carcinoma the site of the primary
tumor could be ascertained . -
pubmed
For
patients with a suspected skeletal
metastasis the search for the primary
tumor may preferably start with FNAB . -
pubmed
SURGICAL TREATMENT : Risk factors for failure after operation for pathologic
fractures were identified in 192
patients treated for 228 metastatic
lesions of the long bones . -
pubmed
Patients with a good prognosis should be considered for wide resection and reconstruction as applied in primary
malignant bone tumors . -
pubmed
To this end , the moral relevance of the difference between
human embryos that have the potential for continued
human growth and development and
human embryos that do not have this potential is explored and a distinction between viable and non - viable
IVF human embryos is introduced . -
pubmed
On this basis , it is argued that scientifically and ethically sound research on spare non - viable
IVF human embryos may proceed . -
pubmed
METHODS : In 25
patients , 41 peri - implant defects with supporting
bone loss & gt;50 % of the implant length were treated with flap surgery plus autogenous bone grafts alone ( FG ) ( controls , n = 12 ) plus non - resorbable ( FGM ) ( test 1 , n = 20 ) or bioabsorbable barriers ( FGRM ) ( test 2 , n = 9 ) and supportive antimicrobial therapy . -
pubmed
Although there is little direct evidence that
corticosteroid therapy can activate
human malaria , animal studies have successfully demonstrated the
recrudescence effect of immunosuppression on
malaria infection . -
pubmed
In this study , we monitored markers of automatic auditory processing in 15 female never - medicated
psychotic patients . -
pubmed
Prominent neurophysiological and behavioral signs of increased cortical activation were observed in
psychotic patients . -
pubmed
This report is focused on the apoptotic effect induced by
MG132 , an inhibitor of 26S proteasome , in
human hepatoma HepG2 cells . -
pubmed
In fact , experimental models exist which demonstrate that
soft tissue sarcomas can be induced in
mice and
rats by implanting artificial materials such as synthetics or metal . -
pubmed
In conclusion , there are no data so far indicating a real risk for
humans to develop
malignant tumors due to implanted meshes . -
pubmed
All
patients received immunosuppressive therapy and non were on
calcium and/or
vitamin D supplements at the time of admission to our
osteoporosis outpatient clinic . -
pubmed
According to WHO criteria ,
osteoporosis at the femoral neck was present in 67 % ( 10/15 ) of the
patients with a mean T - score of -2.55 + /- 0.35 . -
pubmed
Secondary
hyperparathyroidism ( 33 % ) ,
vitamin D deficiency ( 53 % ) as well as
impaired renal function ( 47 % ) were frequent findings in the
patients . -
pubmed
In summary , we found a high prevalence of
osteoporosis and
vertebral fractures in liver transplant recipients with many of the
patients showing evidence of
vitamin D deficiency ,
secondary hyperparathyroidism and
accelerated bone turnover . -
pubmed
[ Assessment of function of the only kidney in
children after nephrectomy due to
Wilms tumor ] . -
pubmed
UNLABELLED : The aim of the study was to evaluate kidney function in
children after unilateral nephrectomy caused by
Wilms ' tumour . -
pubmed
The study included 40 former
patients of the Department of Paediatric Surgery , who underwent complex therapy of
Wilms ' tumour at the age from 6 months to 8 years ( mean 3.42 + /- 2.5 years ) . -
pubmed
Amino acid ratios in plasma and tissues in a
rat model of
liver cirrhosis before and after exercise . -
pubmed
In
human liver cirrhosis (
LC ) , the Fischer ratio (
branched - chain amino acid (
BCAA)/
aromatic amino acid (
AAA ) ) is used as a marker of
hepatic encephalopathy . -
pubmed
Nonmedical risk factors examined included race / ethnicity , age of acquisition of
RSV , sex , birth during the first half of the
RSV season , breast - feeding ,
malnutrition , maternal education , socioeconomic status , crowding / siblings , day care , and tobacco smoke exposure . -
pubmed
RESULTS : There was sufficient evidence available to conclude that ( 1 ) male sex , ( 2 ) age & lt;6 months , ( 3 ) birth during the first half of the
RSV season , ( 4 ) crowding / siblings , and ( 5 ) day care exposure are significant risk factors for severe
RSV LRI . -
pubmed
Low maternal education ( as a proxy for lower socioeconomic status ) , lack of breast - feeding , and
malnutrition did not appear to increase the risk of severe
RSV LRI or
RSV hospitalization . -
pubmed
CONCLUSIONS : Male sex , young age , birth in the first half of the
RSV season , day care attendance , and crowding / siblings are independent risk factors for the development of severe
RSV LRI . -
pubmed
Carbamazepine (
CBZ ) is frequently used to treat
patients with
epilepsy ,
neuralgia ,
psychiatric diseases , etc . -
pubmed
We describe the case of a 12 - year - old
girl who exhibited half tone
lowered pitch perception abnormality caused by
CBZ . -
pubmed
RT - PCR studies of lens RNA isolated from 129S1 / SvImJ , 129S2 / SvPas and 129S4 / SvJae
strains confirmed the presence of this mutation in these diverse 129
strains and similar mutations were found in both CBA and 101
strains , but not in C3H or C57BL/6J
mouse strains . -
pubmed
The effects of
Candida albicans on sperm parameters and the outcome of
infertility treatment are unclear . -
pubmed
This report describes a lack of fertilization after assisted reproductive techniques and increased sperm DNA fragmentation in an infertile patient with
male accessory gland infection due to
Candida albicans . -
pubmed
Using a dot - matrix plotter as a tool to display pairwise comparisons of ordered predicted coding sequences along
rice pseudochromosomes , we found that the
rice genome contains extensive
chromosomal duplications accounting for 53 % of the available sequences . -
pubmed
Soon after completion of the BPRS , the events of September 11 occurred , followed by the
human cases of
anthrax . -
pubmed
Experimental crescentic
glomerulonephritis ( known as autologous anti - glomerular basement membrane
glomerulonephritis ) induced by planting an antigen in glomeruli of
mice is Th1 directed ,
delayed - type hypersensitivity ( DTH)-like , and antibody independent . -
pubmed
Isolation of ani -
hepatotoxic principle form the juice of
Ecballium elaterium . -
pubmed
The antihepatotoxic activity of elaterium ( dried juice of the fruits of
Ecballium elaterium ,
Cucurbitaceae ) and
cucurbitacin B ( isolated from the juice ) was studied against
CCl4 - induced
hepatotoxicity . -
pubmed
Sindbis virus (
SINV ) is widespread in Europe , Africa , Australia , and Asia , but clinical
infection occurs as epidemics in a few geographically restricted areas . -
pubmed
We recently proved , by virus isolation from patients , that
SINV is the causative agent of
Pogosta disease , a
mosquito - borne rash - arthritis occurring as larger epidemics every seventh year in Finland . -
pubmed
SINV RNA detection or virus isolation from blood and/or
skin lesions was successful in 8
patients . -
pubmed
This was a retrospective review of 45
patients with small bowel
neoplasm over a 20 - year period . -
pubmed
BACKGROUND :
Primary acquired melanosis (
PAM ) presents as a unilateral patchy area of conjunctival pigmentation mostly found in middle - aged or elderly white
patients . -
pubmed
CASE REPORT : A 72 - year - old white
man presented for his annual examination with no
visual complaints . -
pubmed
The mean age of
hypertensive adults was 52 years ( range 43 - 66 ) . -
pubmed
Simple experiment for testing the effect of Antibiotic -
EDTA combination on
Rabbits skin artificial
ulcer(s ) infected by
Ps . - pubmed
[ The mechanism and significance of cellular signal transduction in kidney glomerular mesangial cells of
rat with
obstructive jaundice ] . -
pubmed
Except the control and the sham operation group , the other two experiment groups underwent the common bile duct bound to form the
rat model of
obstructive jaundice . -
pubmed
To investigate this process we established
mouse models of
sterile injury and explored the role of hyaluronan in mediating
inflammation following
injury . -
pubmed
In the late phase study after 2000 ( n=16 ) , anticoagulant treatment to prevent graft
necrosis was performed in the
patients having a pHi value under the critical level . -
pubmed
RESULTS : In the early phase study ,
vascular obstruction was not seen in 16
patients with pHi>7.10 . -
pubmed
Of 3
patients with pHi<7.10 , 2 underwent regrafting because of jejunal graft
necrosis by
vascular obstruction . -
pubmed
Intraoperative
vascular occlusion was found in 1
patient with a decline in pHi value and anticoagulant treatment was effective in 2 others . -
pubmed
The management of the
patient and potential causes for the
radiculopathy are discussed . -
pubmed
The case acts as a reminder that the spinal nerve roots should be considered when performing intra - articular facet joint injections and demonstrates the importance of including
nerve injury in the
patient consent process as a rare , but significant complication . -
pubmed
Usefulness of the two to 5 MHz ultrasound probe in examination and block of the sciatic nerve in
orthopedic trauma patients : a preliminary study . -
pubmed
METHODS : Immunocompetent
BALB / c mice bearing Meth A
fibrosarcoma were established . -
pubmed
Interventions to decrease the ambulatory
venous hypertension can help
patients with either active or healed
ulcers . -
pubmed
In summary , compared with rHDLwt , rHDL74 and rHDL52 exhibit higher anti -
inflammation capabilities , whereas
rHDL228 shows hyper - proinflammation by exacerbating LPS - induced
endotoxemia in
mice . -
pubmed
METHODS : Cartilage was obtained from
patients with
osteoarthritis (
OA ) who were undergoing joint replacement ; normal cartilage was obtained from
cadavers who had no history of
joint disease . -
pubmed
Out of the patients from three hospitals who had microbiologically or histopathologically confirmed
tuberculosis , 56
patients presenting with typical disseminated pulmonary nodules on radiographs were retrospectively enrolled . -
pubmed
[ The study of therapeutic effect of synthetic
bradykinin " gene " contained in retrovirus vector on spontaneously
hypertensive rats ] . -
pubmed
Administration of DNA plasmid pPS-3 - neo ( brd ) with synthetic
bradykinin " gene " to 2 - days old male spontaneously
hypertensive rats ( SHR ) leads to 2 weeks delay in development of
arterial hypertension . -
pubmed
This data indicate one of possible ways of gene therapy of
arterial hypertension as well as other pathological states by introduction of transgene directly into genome of the
organism . -
pubmed
Morbidity , mortality , mean survival , and the impact of histology on survival after pleurectomy in 64
patients with
malignant pleural mesothelioma . -
pubmed
To date , the optimal procedure for resection of
malignant pleural mesothelioma is controversial , extrapleural pneumonectomy has been most consistently associated with long - term survival and has provided the most radical cytoreduction ; but , unfortunately , not all
patients qualify for this invasive surgical approach . -
pubmed
METHODS : Between 1992 and 2000 , 64
patients underwent pleurectomy as a palliative treatment for
MPM . -
pubmed
Non - invasive assessment of endothelial activity in
patients with
coronary heart disease and cardiovascular risk factors . -
pubmed
The majority of
BP patients are elderly , and several considerations need to be taken into account before a specific therapy is chosen . -
pubmed
We report our multi - surgeon experience of 43 consecutive
patients ( 44 hips ) who received systemic
vancomycin for two weeks in combination with a
vancomycin- and
gentamicin - eluting spacer system in the course of a two - stage revision procedure for
deep infection with a median follow - up of 49 months ( 25 to 83 ) . -
pubmed
Successful elimination of the infecting organisms occurred in 38 ( 92.7 % ) of 41 hips with three
patients developing
superinfection with a new organism . -
pubmed
This dual receptor strategy illuminates the natural
infection and inter -
human propagation of this lymphotropic virus . -
pubmed
Five hundred twenty - three
human subjects ( 412 with no
colonic neoplasia and 111 with
colorectal cancer , who were scheduled for colonoscopy or surgery ) were recruited to donate a single sample of stool . -
pubmed
These results indicate that
( 1 ) H magnetic resonance spectroscopy of
human fecal extracts , combined with appropriate data analysis methodology , has the potential to detect
colorectal neoplasia accurately and reliably , and could be a useful addition to the current screening tools . -
pubmed
We present a 35 - year - old
woman who suffered from
headache and
dizziness initially , and then
lower back pain ,
lower limb weakness and
paraparesis gradually developed within 1 - 2 weeks . -
pubmed
PURPOSE : To describe a
patient with a history of
epithelial basement membrane dystrophy who developed symptomatic
corneal verticillata after
vandetanib therapy for
anaplastic astrocytoma . -
pubmed
The
patient remained under surveillance for
tumor recurrence . -
pubmed
Tubifex tubifex are obligate invertebrate hosts in the life cycle of
Myxobolus cerebralis , the myxozoan parasite that causes
whirling disease in salmonid fishes . -
pubmed
There was a significant difference in prevalence of
infection and level of parasite production among the populations we exposed to
M. - pubmed
The distribution and
infection dynamics of susceptible
T. - pubmed
These functions are essential for normal embryo development in
flies and
mice , and mutations or altered expression of SAGA subunits correlate with
neurological disease and
aggressive cancers in
humans . -
pubmed
Cytotoxic effects were compared using a colony - formation assay in three established cell lines (
Balb 3T3 ,
mouse whole embryo ,
ARLJ301 - 3 ,
rat liver and
FRSK ,
rat keratinocytes ) and one primary cell culture (
RC-1 ,
rabbit cornea ) with the Draize eye irritancy score in vivo . -
pubmed
Time trends of
syphilis and
HSV-2 co - infection among men who have sex with men in the German
HIV-1 seroconverter cohort from 1996 - 2007 . -
pubmed
We sought to explore trends in
STI co - infections around the time of
HIV seroconversion in patients from the German
HIV-1 seroconverter cohort from 1996 - 2007 . -
pubmed
Among
HIV seroconverters with positive
syphilis antibodies , 32 % ( n=88 ) were rated as having had coincident
infections with
HIV and
syphilis . -
pubmed
Coincident
syphilis infection at
HIV diagnosis increased substantially ( p<0.001 ) from 2.3 % in 2000 to 16.9 % in 2003 ; and thereafter declined to 4.3 % in 2007 . -
pubmed
DISCUSSION : We found a stable prevalence of
HSV-2 infection and increasing prevalence of
syphilis infection around the time of
HIV acquisition among MSM in Germany . -
pubmed
Time course and rate of co -
infections suggest that a re - emerging
syphilis co - epidemic among MSM after 2000 could have contributed to an increase of
HIV incidence by enhancing
HIV transmission probability . -
pubmed
METHODS : All
patients diagnosed with
pancreatitis consecutively underwent EUS on the 2nd day of their admission . -
pubmed
Experiments of bone marrow transplantation between either genotype of
mice showed that KO corneal tissue resident cells , but not KO bone marrow - derived cells , are responsible for KO - type
wound healing with reduced
inflammation and
fibrosis . -
pubmed
Middle and high trans - sphincteric
fistulae were diagnosed in 20 ( 71.4 % ) and eight ( 28.6 % )
patients . -
pubmed
No
incontinence was found at a mean follow - up of 20.6 ( 3 - 60 ) months among the 67.8 %
patients with no evidence of
recurrence . -
pubmed
MATERIALS AND METHODS : Eighteen biopsies of
glioblastoma multiforme were obtained from
patients at the Institute of Neurosurgery Dr. Asenjo ( INCA ) . -
pubmed
RESULTS : The number of
patients with
glioblastoma multiforme increased between 2007 and 2009 , from 3.5 % to 7.9 % of total
brain tumors . -
pubmed
METHODS : In 112 consecutive
patients with
ASDs , the morphology of the defects was evaluated for transcatheter closure in the right parasternal view in addition to the conventional left views using 2D and 3D TTE . -
pubmed
RESULTS : In 88
patients ( 80.0 % ) , optimal images from the right parasternal approach for morphologic evaluation of
ASDs were obtained . -
pubmed
Flexor tendon injuries still remain a challenging condition to manage to ensure optimal outcome for the
patient . -
pubmed
Subpopulation structure of regulatory T cells and T helpers of peripheral blood in
patients with newly diagnosed
pulmonary tuberculosis depending on the clinical form of disease and sensitivity of
Mycobacterium tuberculosis to antituberculosis drugs has been analyzed in this work . -
pubmed
In patients with
infiltrative pulmonary tuberculosis , including multidrug - resistant
M. - pubmed
Reduction in the number of T - helpers in the blood of
patients with dissemination and
fibrosis - cavity pulmonary tuberculosis mediates inefficient implementation of cell - mediated protective immunity . -
pubmed
Free skin grafts for immediate
wound coverage following
tumour resection from the
canine distal limb . -
pubmed
METHOD : Evaluation of medical records of
dogs that received a full - thickness , meshed , free skin graft in the distal limb immediately after
tumour removal . -
pubmed
None of the
dogs had full thickness
necrosis or required further reconstruction . -
pubmed
CLINICAL SIGNIFICANCE : Free grafting can be used reliably to reconstruct extensive
surgical wounds in the distal limb in
dogs after large
tumour resection without the need for a delay to allow granulation tissue to form . -
pubmed
Effects of nasal insufflation on arterial gas exchange and breathing pattern in
patients with
chronic obstructive pulmonary disease and hypercapnic
respiratory failure . -
pubmed
High flow nasal insufflations ( NI ) can improve gas exchange and alleviate
dyspnea in
patients with acute
respiratory failure . -
pubmed
In the present study we investigated the effects of high flow nasal insufflations in
COPD patients with chronic hypercapnic
respiratory failure (
HRF ) . -
pubmed
Seventeen
patients with severe
COPD and
HRF were recruited . -
pubmed
Our data indicate that high flow NI improved efficiency of breathing and may be used as an adjunct to low flow
oxygen for preventing hypercapnic
respiratory failure in severely ill
COPD patients . -
pubmed
Acute bilateral hearing loss as a " worsening sign " in a
patient with critical
basilar artery stenosis . -
pubmed
We report a
patient who presented with an acute - onset transient
vertigo and
unsteady gait with bilateral
hearing loss . -
pubmed
The neurological function of the
patient recovered to normal , and no
hemorrhagic complications were observed . -
pubmed
Therefore , practitioners should be alert when treating
patients with
acute bilateral hearing loss , which may be related to an underlying catastrophic
stroke . -
pubmed
UNLABELLED : BACKGROUND : The foodborne pathogen
Bacillus cereus can cause
diarrhoeal food poisoning by production of enterotoxins in the small intestine . -
pubmed
cereus
strains were cultivated in a real composite food matrix ,
lasagne verde , and their survival during subsequent simulation of gastrointestinal passage was assessed using in vitro experiments simulating transit through the
human upper gastrointestinal tract ( from mouth to small intestine ) . -
pubmed
However , considerable
strain variability was observed in sporulation tendency during growth in laboratory medium and food , which has important implications for the gastrointestinal survival potential of the different
B. - pubmed
This paper reviews the literature concerning the influences of antidepressants in
PWE and in
animal models . -
pubmed
Critically ill patients are frequently at risk of
neurological dysfunction as a result of primary neurological conditions or secondary insults . -
pubmed
Determining which aspects of brain function are affected and how best to manage the
neurological dysfunction can often be difficult and is complicated by the limited information that can be gained from clinical examination in such
patients and the effects of therapies , notably sedation , on neurological function . -
pubmed
Methods to measure and monitor brain function have evolved considerably in recent years and now play an important role in the evaluation and management of
patients with
brain injury . -
pubmed
Animals developed mixed
dyslipidaemia and
atherosclerotic lesions , which were associated with
endothelial dysfunction , aortic overproduction of
superoxide anions and
inflammation . -
pubmed
Within this context , reliable
animal models that recapitulate situations of impaired
wound healing have become essential . -
pubmed
In this study , we established a new in vivo humanised model of delayed
wound healing in a
diabetic context that reproduces the main features of the
human disease . -
pubmed
Diabetes was induced by multiple low doses of
streptozotocin in bioengineered
human - skin - engrafted immunodeficient
mice . -
pubmed
OBJECTIVES / HYPOTHESIS : To investigate cochlear implantation ( CI ) in
patients with unilateral
deafness with and without
tinnitus . -
pubmed
STUDY DESIGN : Prospective case series of
patients undergoing cochlear implantation for unilateral
deafness and
tinnitus in a tertiary academic unit . -
pubmed
METHODS : Nine postlingually deafened
subjects with
unilateral hearing loss , with and without
tinnitus ipsilaterally , and functional hearing in the contralateral ear were implanted with a standard electrode . -
pubmed
CONCLUSION : In our case series , CI was successful for all nine
patients , with improvement of speech recognition in noise , self - perceived improvement of hearing , and for
tinnitus control . -
pubmed
Compounds 1 , 4 and 5 exhibited good antibacterial activity against antibiotic resistant clinical
bacteria and
cytotoxic effects against selected
cancer cell lines . -
pubmed
METHODS : Forty - two
patients treated with HR in 3 - 5 fractions for 20 ( 48 % ) intact and 22 ( 52 % ) resected
brain metastases with a median maximum dimension of 3.9 cm ( 0.8 - 6.4 cm ) between May 2008 and August 2011 were reviewed . -
pubmed
Symptomatic radiation
necrosis occurred in 3
patients ( 7 % ) . -
pubmed
Ninety - six
smokers with and without
PTSD provided blood samples for
neurosteroid analyses and completed self - report measures of
anxiety sensitivity and electronic diary ratings of negative affect . -
pubmed
Anemia prevalence for the fortified
rice center was 27.8 % ( 20/72 ) at baseline , and 11.1 % ( 8/72 ) at endpoint , p = 0.012 ; for the control center , 47.1 % ( 33/70 ) were
anemic at baseline , and 37.1 % ( 26/70 ) at the end of the study , p = 0.23 . -
pubmed
In animal studies ,
vitamin C has protected against various
infections and
bacterial toxins . -
pubmed
In a study with
rats ,
vitamin C protected against the purified
tetanus toxin . -
pubmed
This non - randomised , unblinded , controlled trial undertaken in Bangladesh involved 117
tetanus patients . -
pubmed
In the
tetanus patients aged 1 to 12 years ( n = 62 ) ,
vitamin C treatment was associated with a 100 % reduction in case fatality rate ( 95 % CI from -100 % to -94 % ) . -
pubmed
METHODS : Charts of the
patients with
localised renal tumors , who were managed by either open or robot - assisted nephron - sparing surgery between May 2010 and June 2012 , were retrospectively reviewed . -
pubmed
Effects of cooking methods on the
iron and
zinc contents in
cowpea (
Vigna unguiculata ) to combat
nutritional deficiencies in Brazil . -
pubmed
BACKGROUND : Because
iron deficiency anemia is prevalent in developing countries , determining the levels of
iron and
zinc in
beans , the second most consumed staple food in Brazil , is essential , especially for the low - income people who experience a
deficiency of these minerals in their diet . -
pubmed
Here , through genome - wide identification of AS events in the
soybean (
Glycine max ) genome using high - throughput RNA sequencing of 28 samples from different developmental stages , we found that more than 63 % of multiexonic genes underwent
AS . -
pubmed
Altogether , our study revealed that a large number of genes were alternatively spliced in the
soybean genome and that variations in gene structure and transcriptional level may play important roles in regulating
AS . -
pubmed
Nongenotoxic effects and a reduction of the
DXR - induced
genotoxic effects of
Helianthus annuus Linne (
sunflower ) seeds revealed by micronucleus assays in
mouse bone marrow . -
pubmed
BACKGROUND : This research evaluated the
genotoxicity of oil and tincture of
H. - pubmed
Accumulating evidence suggests that
statins have pleiotropic effects ; therefore , these drugs could be a potential anti - inflammatory treatment for
patients with
bronchiectasis . -
pubmed
We did a proof - of - concept randomised controlled trial to establish if
atorvastatin could reduce
cough in
patients with
bronchiectasis . -
pubmed
INTERPRETATION : 6 months of
atorvastatin improved
cough on a quality - of - life scale in
patients with
bronchiectasis . -
pubmed
Cardiovascular dysfunction and failure are commonly encountered in the
patient with
intra - abdominal hypertension or
abdominal compartment syndrome . -
pubmed
Application of a goal - directed resuscitation strategy , including abdominal decompression when indicated , improves cardiac function , reverses
end - organ failure , and minimizes intra - abdominal
hypertension - related
patient morbidity and mortality . -
pubmed
PURPOSE :
Epstein - Barr virus (
EBV ) infects not only B cells but also T cells and natural killer ( NK ) cells , and
T - and NK - cell lymphoproliferative diseases (
T / NK - LPD ) that are refractory to conventional chemotherapies may develop . -
pubmed
Mogamulizumab induced antibody - dependent cellular cytotoxicity ( ADCC ) activity against
CCR4 - positive cell lines , and inhibited the growth of
EBV - positive
NK - cell lymphomas in a
murine xenograft model . -
pubmed
EBV - positive gammadeltaT cells were obtained from a
patient with
hydroa vacciniforme and subjected to an antibody - dependent cell - mediated cytotoxicity ( ADCC ) assay . -
pubmed
Chordomas of the upper cervical spine : clinical characteristics and surgical management of a series of 21
patients . -
pubmed
This study aimed to describe the clinical characteristics and surgical management of
patients with
chordomas of the upper cervical spine . -
pubmed
METHODS : Twenty - one
patients with
chordomas of the upper cervical spine who were treated in Peking University Third Hospital from January 1999 to October 2012 were retrospectively analyzed . -
pubmed
Two
patients developed postoperative
velopharyngeal incompetence , and loosening of the occipitocervical screws was observed in one
patient . -
pubmed
Steroidal alkaloids from the marine sponge
Corticium niger that inhibit growth of
human colon carcinoma cells . -
pubmed
Bioinformatic analysis of data from the
NCI-60 cell
cytotoxicity screen revealed a subset of extracts that showed selective cytotoxic activity toward
human colon carcinoma cell lines . -
pubmed
Bioassay - guided fractionation of a
colon cancer selective extract from a Philippines collection of the marine sponge
Corticium niger provided two new
steroidal alkaloids ,
plakinamines N ( 1 ) and O ( 2 ) , along with two known compounds of the
plakinamine class ( 3 , 4 ) . -
pubmed
We therefore aimed to ascertain the prevalence of early repolarization pattern ( ERP ) in resting electrocardiograms ( ECGs ) of
psoriatic patients compared with an appropriate control group . -
pubmed
We performed a retrospective study of resting ECGs of 100 consecutive
psoriatic patients and 100 healthy controls . -
pubmed
An ERP in & gt;= 2 contiguous leads occurred in 40 % of
psoriatic patients , compared with 14 % of control subjects ( p & lt ; 0.001 ) . -
pubmed
Since CCRT with weekly chemotherapy regimens have demonstrated a favorable toxicity profile as well as promising survival in certain types of
cancer , we aimed to evaluate the efficacy and
toxicity of radiotherapy concurrently with weekly chemotherapy with
5 - fluorouracil ( 5 - FU ) and
platinum agents for
patients with postoperative locoregional
recurrence of
oesophageal squamous cell carcinoma in our center . -
pubmed
Twenty - seven consecutive
patients who were diagnosed with postoperative locoregional recurrence of
oesophageal squamous cell carcinoma and received CCRT with weekly chemotherapy of
5 - FU and
platinum agents were retrospectively analyzed . -
pubmed
RESULTS : Of the 1450
patients who responded to both surveys and experienced no
recurrence , 963 underwent breast - conserving surgery , 263 mastectomy without reconstruction , and 222 mastectomy with reconstruction . -
pubmed
There are four main areas to focus on when thinking about management strategies in
NAFLD : lifestyle modification , targeting the components of the
metabolic syndrome , liver - directed pharmacotherapy for high risk
patients and managing the complications of
cirrhosis . -
pubmed
Melatonin has been shown to diminish
edema in
rats . -
pubmed
This study is a sequel of our earlier studies to understand the molecular organization of heat
shock genes / proteins and their role in development and thermal adaptation in a
sheep pest ,
Lucilia cuprina ( blowfly ) , which exhibits unusually high adaptability to a variety of environmental stresses , including heat and chemicals . -
pubmed
Theory of mind and social functioning in
patients with
temporal lobe epilepsy . -
pubmed
OBJECTIVE : This study aimed to explore the effects of theory of mind ( ToM ) and related potential risk factors , including cognitive functions , psychiatric status , and
seizure - related clinical variables , on social functioning in
patients with
temporal lobe epilepsy (
TLE ) . -
pubmed
METHODS : Sixty - seven
patients with intractable
TLE who were potential candidates for
epilepsy surgery and 30 matched controls were included . -
pubmed
Antiviral Efficacy of a
Respiratory Syncytial Virus (
RSV ) Fusion Inhibitor in a Bovine Model of
RSV Infection . -
pubmed
Respiratory syncytial virus (
RSV ) is the leading cause of
bronchiolitis and
pneumonia in infants . -
pubmed
Experimental
infection of Holstein calves with bovine
RSV (
bRSV ) causes a severe
respiratory infection that is similar to human
RSV infection , providing a relevant model for testing novel therapeutic agents . -
pubmed
These data support the use of the bovine
RSV model for evaluation of experimental therapeutics for treatment of
RSV . -
pubmed
Survival of
rat cerebrocortical neurons after
rickettsial infection . -
pubmed
The main aim of this study was to investigate biochemical and morphological changes that may occur as a result of an in vitro
infection of
rat cerebrocortical neurons by selected members of the genus Rickettsia . -
pubmed
Long - term remissions after FCR chemoimmunotherapy in previously untreated
patients with
CLL : updated results of the CLL8 trial . -
pubmed
Despite promising results with targeted drugs , chemoimmunotherapy with
fludarabine ,
cyclophosphamide (
FC ) , and rituximab ( R ) remains the standard therapy for fit
patients with untreated
chronic lymphocytic leukemia (
CLL ) . -
pubmed
Herein , we present the long - term follow - up of the randomized CLL8 trial reporting safety and efficacy of FC and FCR treatment of 817 treatment - naive
patients with
CLL . -
pubmed
First - line chemoimmunotherapy with FCR induces long - term remissions and highly relevant improvement in OS in specific genetic subgroups of fit
patients with
CLL , in particular those with IGHV MUT . -
pubmed
In all
patients , the putative arterial source of
emboli was demonstrated by angiography . -
pubmed
Intravenous
Esomeprazole for Prevention of
Peptic Ulcer Rebleeding : A Randomized Trial in Chinese
Patients . -
pubmed
This study aimed to evaluate a high - dose
esomeprazole intravenous regimen vs. an active control (
cimetidine ) for the prevention of rebleeding in Chinese
patients with a high risk of
peptic ulcer rebleeding who had undergone primary endoscopic hemostatic treatment . -
pubmed
CONCLUSION : In this phase 3 , multicenter , randomized trial conducted in China ,
esomeprazole showed a numerical trend towards superior clinical benefit over
cimetidine in the prevention of
rebleeding in
patients who had successfully undergone initial hemostatic therapy of a
bleeding peptic ulcer , with a similar safety and tolerability profile . -
pubmed
In filarial nematodes , which include parasites responsible for major diseases of
humans ( such as
Onchocerca volvulus , agent of
river blindness ) and companion animals (
Dirofilaria immitis , the
dog heartworm ) , Wolbachia has an obligate mutualist role and is the target of new treatment regimens . -
pubmed
Corrigendum to " Antimetastatic Potentials of
Dioscorea nipponica on
Melanoma In Vitro and In Vivo " . -
pubmed
BACKGROUND : Noninvasive stress tests play a determinant role in the initial management of
patients with
chronic angina . -
pubmed
Although the majority had normal EST results or an increased threshold to
angina , at 1 month after the index PCI , 29 % of
patients still had an abnormal result . -
pubmed
CASE REPORT : The case is presented of a
patient with diagnosis of
iris nevus in the left eye in
youth with a poor follow - up , who referred a
decreased visual acuity in that eye . -
pubmed
The present study investigated the effects of pulmonary exposure to single - walled
carbon nanotubes ( SWCNTs ) and double - walled
carbon nanotubes ( DWCNTs ) on atherosclerogenesis using normal
human aortic endothelial cells ( HAECs ) and
apolipoprotein E - deficient ( ApoE -/- ) mice , a model of
human atherosclerosis . -
pubmed
METHODS AND MATERIALS : We identified
patients with
adrenal metastases treated with SABR from 2009 to 2015 . -
pubmed
RESULTS : Forty - three
patients with 49
adrenal metastases ( 84 % from lung ) were treated with SABR to a median prescribed dose of 60 Gy in 10 fractions . -
pubmed
PFS was better in
patients with a solitary
adrenal metastasis ( P = .03 ) . -
pubmed
Low - grade
gastrointestinal toxicity was common , but grade 2 toxicity was avoided in
patients with a maximum stomach - bowel point dose of & lt;=50 Gy ( P = .03 ) . -
pubmed
CONCLUSION : SABR was well tolerated and resulted in good 1 - year local control ; PFS was promising for
patients with solitary
metastases . -
pubmed
METHODS : Multidimensional genomic profiling was performed in
human aortic valves to document the expression of lncRNAs and the DNA methylation pattern in
calcific aortic valve disease . -
pubmed
One more time , renal biopsy showed
tubular necrosis and
patient recovered renal function after discontinuation . -
pubmed
In all other cell lines , the concentration of
metformin required to inhibit
oxygen consumption acutely in vitro was substantially higher than that achieved in the plasma of
diabetic patients . -
pubmed
However , administering anti - diabetic doses of
metformin to
tumor - bearing
mice resulted in intratumoral accumulation of
metformin and reduced hypoxic
tumor fractions . -
pubmed
MATERIAL AND METHODS : In a project , evaluating
patients with suspected
chronic pancreatitis (
CP ) and healthy
volunteers ( HC ) , stools were collected for 72 hours coupled to registration of nutritional intake over five consecutive days . -
pubmed
RESULTS : We found 12
patients with
CP , 11
patients without
CP and 13 healthy individuals in our database . -
pubmed
We used clinical outcome data from 493 cases of
STEC O157 : H7 to assess the relative risk of severe disease including
haemolytic uraemic syndrome from each of the defined clades in the population and show the dramatic effect Shiga toxin repertoire has on virulence . -
pubmed
We describe two
strain replacement events that have occurred in the
cattle population in the UK over the last 30 years , one resulting in a highly virulent
strain that has accounted for the majority of clinical cases in the UK over the last decade . -
pubmed
Retrospective evaluation of factors influencing successful skin grafting for
patients with
skin cancer of the foot . -
pubmed
We analyzed data for 71
patients with
skin cancer of the foot who underwent reconstruction of defects with skin grafting . -
pubmed
A 50 - year - old
man experienced
cardiac arrest . -
pubmed
METHODS : A total of 162
subjects were categorized into four groups based on
depression scores and blood pressure . -
pubmed
Perineural tumor spread ( PNS ) substantially alters a
patient 's prognosis and treatment plan . -
pubmed
This study describes the development and initial evaluation of a multiplex reverse transcription ( RT)-PCR and novel accompanying automated electronic microarray assay for simultaneous detection and differentiation of seven important viruses that affect
swine ( foot - and - mouth disease virus [
FMDV ] ,
swine vesicular disease virus [
SVDV ] , vesicular
exanthema of
swine virus [
VESV ] ,
African swine fever virus [
ASFV ] ,
classical swine fever virus [
CSFV ] ,
porcine respiratory and reproductive syndrome virus [
PRRSV ] and
porcine circovirus type 2 [
PCV2 ] ) . -
pubmed
This assay accurately detected and identified a total of 68 isolates of the seven targeted virus species including 23 samples of
FMDV , representing all seven serotypes , and 10
CSFV strains , representing all three genotypes . -
pubmed
Patients who undergo total hip arthroplasty ( THA ) may experience a large amount of
blood loss . -
pubmed
The circular extrachromosomal element of
Naegleria gruberi strain EGB was linearized , molecularly cloned , and fully sequenced . -
pubmed
A cohort of 710
patients with
idiopathic dilated cardiomyopathy , without previous
ventricular arrhythmias , was retrospectively studied to understand how risks vary in time . -
pubmed
Genetic Association of Drug Response to
Erlotinib in Chinese Advanced
Non - small Cell Lung Cancer Patients . -
pubmed
This study provides comprehensive , systematic analyses of genetic variants associated with responses to
erlotinib in Chinese advanced
non - small cell lung cancer patients . -
pubmed
Newly - identified SNPs may serve as promising markers to predict responses and safety in
erlotinib - treated advanced
non - small cell lung cancer patients after chemotherapy doublet . -
pubmed
METHODS : We performed a single - center retrospective analysis including 489
patients with
ulcerative colitis . -
pubmed
Detection in whole blood of autoantibodies for the diagnosis of
connective tissue diseases in near
patient testing condition . -
pubmed
METHODS : A cross - sectional study was performed in 87
patients with
TA and 90 controls . -
pubmed
RESULTS : All the inflammatory markers were significantly higher in the
TA patients than in the controls . -
pubmed
INTRODUCTION : The survival of
multiple myeloma patients is increasing due to new medications , the widespread implementation of autologous stem cell transplantation and better supportive treatments . -
pubmed
Areas covered : In this review , we have summarized the current data on maintenance therapy in newly diagnosed
MM patients undergoing ASCT , focusing on
bortezomib ,
thalidomide and
lenalidomide as well as newer agents Expert opinion : Maintenance treatment has been shown to deepen and prolong responses and increase PFS and OS . -
pubmed
Propranolol is the first - line treatment for
infants suffering from
infantile hemangioma . -
pubmed
Remodeling classification system considering left ventricular volume in
patients with
aortic valve stenosis : Association with adverse cardiovascular outcomes . -
pubmed
CONCLUSIONS : In
patients with AVA & lt;= 1.5 cm2 , when the new LV remodeling classification system is applied , only a minority had normal geometry and less than half had " classic " concentric
LVH or remodeling . -
pubmed
Grip force tracking tasks were conducted by
stroke patients , age - matched healthy controls , and healthy young adults at 25 % , 50 % , and 75 % maximum voluntary contractions ( MVC ) , respectively . -
pubmed
Circulating
tumor DNA ( ctDNA ) holds great promise as a noninvasive diagnostic tool to guide treatment for
patients with
lung cancer . -
pubmed
Together , these studies further highlight the potential clinical utility of serial ctDNA monitoring in
patients with
NSCLC undergoing treatment with both targeted therapies and immunotherapies . -
pubmed
Recently , the putative association between selective
serotonin reuptake inhibitor ( SSRI ) exposure during pregnancy and the development of
social disorders in
children has gained increased attention . -
pubmed
Furthermore , preclinical studies using an
animal model of
maternal depression to study effects of perinatal
SSRI exposure on offspring social behavior are limited . -
pubmed
Here , we aimed to investigate whether different doses of
atorvastatin (
ATV ) affect
rats with
T2DM . -
pubmed
A total of 110
Sprague - Dawley rats were successfully established as
T2DM models . -
pubmed
Rats administered
ATV at the doses of 40 and 80 mg/(kg day ) demonstrated significantly improved
liver injury and
pancreatic injury induced by
T2DM . -
pubmed
Conclusion : These data revealed that
ATV could improve the lipid metabolism in
T2DM rats and 40 mg/(kg day ) may serve as the optimal dose for the reduction of lipid levels and the incidence of adverse effects . -
pubmed
Since mid-2015 , numerous outbreaks of
hydropericardium - hepatitis syndrome (
HHS ) , which is caused by a novel fowl adenovirus serotype 4 (
FAdV-4 ) , have been reported in
chickens in parts of China , thereby causing huge economic losses to the poultry industry . -
pubmed
Thus , an effective vaccine to control the further spread of
infections with this hyper - virulent
FAdV-4 is imperative . -
pubmed
In this study , we isolated a novel
FAdV-4 strain SDJN0105 from a broiler farm with
HHS disease in Shandong Province . -
pubmed
These results improve our understanding of the innate immune responses in
chickens infected with
FAdV-4 and the pathogenesis of
FAdV-4 caused by host factors , and the developed
FAdV-4 vaccine is promising as a drug candidate for the prevention and reduction of the spread of
HHS in poultry in China . -
pubmed
BACKGROUND : Indications for revision surgery are unclear in refractory
cubital tunnel syndrome patients , and the optimal surgical method has not been determined . -
pubmed
In this study , fERG data were recorded from
MDD patients in a current major
depressive episode ( n = 25 ) , and compared to data from
SCZ patients ( n = 25 ) and healthy controls ( HC ; n = 25 ) , to determine the degree to which fERG anomalies in acute
MDD overlap or contrast with those observed in stabilized ( though not symptom free )
SCZ . -
pubmed
Interestingly ,
MDD patients demonstrated an increase in photopic a - wave implicit time relative to
SCZ patients , and a decrease in PhNR implicit time relative to controls . -
pubmed
Patients and methods : This single - center cross - sectional study encompassed 201
patients ( 160
males , 41
females ; mean age 56.9 + -13 years ; range 20 to 89 years ) including 52 asymptomatic
hyperuricemia , 86
gouty arthritis without
tophi , and 63
gouty tophi patients . -
pubmed
CONCLUSIONS : In
patients with
RA , the relative increase in etanercept - associated risk of experiencing
congestive heart failure , serious
infection ,
non - melanoma skin cancer , or
interstitial lung disease was similar between elderly and non - elderly . -
pubmed
The
cytotoxicity of
R. - pubmed
Exhaled Volatile Organic Compounds Precedes
Pulmonary Injury in a
Swine Pulmonary
Oxygen Toxicity Model . -
pubmed
Results :
Swine exposed to
hyperoxia developed
pulmonary injury consistent with PO2T. -
pubmed
Histology of
oxygen - exposed
swine showed
pulmonary lymphatic congestion , epithelial sloughing , and neutrophil transmigration . -
pubmed
Conclusion : Exposing
swine to 72 h of
hyperoxia induced a
pulmonary injury consistent with
human clinical endpoints of PO2T. -
pubmed
Results show promise that a simple , non - invasive breath test could potentially predict the risk of
pulmonary injury in
humans exposed to high partial pressures of
oxygen . -
pubmed
Survival and ocular preservation in a long - term cohort of Japanese
patients with
retinoblastoma . -
pubmed
BACKGROUND :
Retinoblastoma is an
ocular tumor in
infants with
cancer predisposition . -
pubmed
METHODS : We studied the outcomes of all
patients with
retinoblastoma at a tertiary center in 1984 - 2016 , when preservation method changed from radiotherapy ( 1984 - 2001 ) to systemic chemotherapy ( 2002 - 2016 ) . -
pubmed
RESULTS : One - hundred sixteen
infants developed unilateral- ( n = 77 ) , bilateral- ( n = 38 ) , or trilateral - onset ( n = 1 )
tumor . -
pubmed
The 10 - year OS and
cancer (
retinoblastoma / SPM)-free survival ( CFS ) rates of all
patients were 94.9 and 88.5 % , respectively . -
pubmed
METHODS : In this study , we analyzed the pooled data of 109
PAD patients enrolled in the SHIFT and IBIS studies . -
pubmed
RESULTS : The total monthly SCIG dose showed comparable trends among weight categories , except for
underweight patients . -
pubmed
Methods : A total of 120 NSG
mice were used for a combined pharmacodynamics and
toxicity study for 56 days . -
pubmed
The survival rate and
leukemia related clinical symptoms in
mice administered CART19 were markedly ameliorated , and the proliferation of
Raji cells in
mice was effectively inhibited . -
pubmed
Conclusions :
NSG mice given CART19 treatment demonstrated a longer survival period without significant
immunotoxicity , suggesting encouraging clinical prospects for CART19 in
patients with R / R
ALL . -
pubmed
WD - fed knockout
mice developed severe
NASH , which was associated with increased BA concentration in the cecum and loss of CEB function . -
pubmed
Orbitides isolated from
flaxseed induce apoptosis against
SGC-7901 adenocarcinoma cells . -
pubmed
In this study , we investigated the effects of
orbitides isolated from
flax (
Linum usitatissimum L. ) on the growth of
SGC-7901 cancer cells and the potential mechanism . -
pubmed
OBJECTIVE : The objective was to assess the effects of a nasal restriction device for inspiratory muscle training , called Feelbreathe , added to a rehabilitation program ( RP ) on exercise capacity , quality of life ,
dyspnea and inspiratory muscle strength in
patients with stable
COPD . -
pubmed
The presented data identifies new leads to understand the mechanisms behind brain and specifically cortical development and can provide novel insights in developmental mechanisms underlying
human brain defects . -
pubmed
OBJECTIVES : The purpose of this pilot
porcine cadaver study was to evaluate the feasible temperature thresholds , which affect osteocyte viability and bone matrix in a preclinical setup , assessing the potential of thermal
necrosis for implant removal for further in vivo investigations . -
pubmed
[ Expression and diagnostic value of plasma miR-145 and miR-183 in
children with
lupus nephritis ] . -
pubmed
OBJECTIVE : To study the expression and diagnostic value of plasma miR-145 and miR-183 in
children with
lupus nephritis (
LN ) . -
pubmed
METHODS : A total of 92
children with
LN who were admitted from January 2016 to May 2019 were enrolled as the LN group , among whom 17 had
type II LN , 15 had
type III LN , 36 had
type IV LN , 18 had
type V LN , and 6 had
type VI LN . -
pubmed
According to
Systemic Lupus Erythematosus Disease Activity Index ( SLEDAI ) , the 92
children with
LN were further divided into a stable LN group with 34
children ( SLEDAI score < 10 ) and an active LN group with 58
children ( SLEDAI score > = 10 ) . -
pubmed
CONCLUSIONS : There are significant reductions in the expression levels of miR-145 and miR-183 in plasma in
children with
LN , which are correlated with the activity level and pathological typing of
LN . -
pubmed
BACKGROUND AND PURPOSE : Differentiation between pseudo - occlusion and true
occlusion of internal carotid artery ( ICA ) is important in treatment planning for acute
ischemic stroke patients . -
pubmed
We compared the findings of multiphasic computed tomography angiography between cervical ICA pseudo - occlusion and true occlusion at the cervical ICA in
patients with
anterior circulation acute ischemic stroke to determine their diagnostic value . -
pubmed
Whereas LHb inactivation did not modify
rat 's behavior during conditioning , it induced contextual
memory deficits and enhanced fear to the tone . -
pubmed
QTcD has been shown to be higher in individuals with mild
cognitive impairment , and the highest in
individuals with
Alzheimer ' s disease . -
pubmed
This study aimed to assess vagal control in
VVS patients and evaluate the diagnostic value of the DC in
VVS . -
pubmed
Methods - Altogether 161 consecutive
VVS patients ( 43 + - 15 years ; 62
males ) were enrolled . -
pubmed
DC was similarly increased in
VVS patients with a positive and negative TTT ( 9.7 + -3.5 ms and 9.4 + -2.9 ms , P=0.614 ) . -
pubmed
Letter to the Editor Regarding : " Effects of exercise in
patients with
amyotrophic lateral sclerosis : A systematic review and meta - analysis " . -
pubmed
According to the recent studies , these derivatives exhibited good antiviral activity against different types of viruses such as the
human immunodeficiency viruses (
HIV ) , the
hepatitis C virus (
HCV ) , the
hepatitis B virus (
HBV ) ,
Respiratory syncytial virus (
RSV ) , and
Cytomegalovirus (
CMV ) . -
pubmed
Methods
Patients with
chronic hepatitis B were treated with
pegylated interferon alpha-2a for 48 weeks . -
pubmed
METHODS : Our study retrospectively recruited advanced
CM ( clinical T3 stage )
patients treated with individualised ( 13 cases ) or conventional ( 18 cases ) exenteration from June 2014 to April 2019 . -
pubmed
Newborn
mice sensitized to
picryl chloride within 24 hr after birth fail to develop
contact sensitivity reaction when tested several weeks later , and fetal
mice do not develop graft - versus - host reaction when given injections of parental lymphocytes . -
pubmed
Spleen cells of fetal or newborn
mice are able to suppress the passive transfer of
contact sensitivity and the local graft - versus - host reaction elicited by immunized parental cells in
F1 hybrid mice , and reduce significantly the severity of graft - versus - host reaction and mortality rate in
cyclophosphamide - treated F1 recipients . -
pubmed
of
urapidil , there was no
hypotensive effect in the
rat to be seen and , therefore , it can be concluded that changes in spontaneous and reactive behaviour are not due to acute changes in cardiovascular functions . -
pubmed
Tallysomycin exhibited broad antibacterial and antifungal activity , and was highly active in vivo against
bacterial infections in
mice . -
pubmed
A comparison between blood
glucose levels in patients attending a
diabetes clinic and in the same patients leading their normal lives showed that for maturity - onset
diabetic patients on oral hypoglycemic therapy , the clinic levels were a poor guide to the patients ' usual blood
glucose . -
pubmed
Invasive prostatic patterns are most frequent in the setting of high stage invasive
bladder tumors and 5 - year survival rates for these
patients are low . -
pubmed
Fenfluramine - induced
hyperthermia and stimulation in the
rabbit . -
pubmed
Fenfluramine produces dose - related
hyperthermia and behavioral stimulation in
rabbits following intravenous administration . -
pubmed
Early postoperative
thrombosis of the prosthesis occurred in 7
patients . -
pubmed
Late
thrombosis of the aorto - renal branch or aorto - femoral prosthesis occurred in 4
patients . -
pubmed
The clinical course of
chronic lymphocytic leukaemia (
CLL ) in 126
patients has been examined over the period 1961 - 88 . -
pubmed
In fact
periodontal disease is caused by specific
bacteria (
Bacteroides Gingivalis ,
Actinobacillus actinomycetemcomitans ) growing in the
periodontal pocket so that the bacterial products such as histolytic enzymes , endotoxins or exotoxins may exert a direct effect . -
pubmed
Anteroapical
left ventricular aneurysms were produced in 23
sheep by coronary arterial ligation . -
pubmed
In nine of these
sheep the midsagittal plane of the left ventricle was imaged by means of an array of sonomicrometry crystals before and after plication of the
aneurysm . -
pubmed
Lacrimal and salivary gland inflammation in the C3H / Ipr autoimmune
strain mouse : a potential mode for
Sjogren ' s syndrome . -
pubmed
To identify a potential
animal model for study of
Sjogren ' s syndrome , an evaluation was made of lacrimal and salivary glands in the C3H / Ipr autoimmune strain
mouse at ages before ( 2 months ) and after ( 5 months ) systemic
autoimmune disease onset at 3 to 4 months . -
pubmed
Quantitative and qualitative analyses of C3H / Ipr lacrimal and salivary ( parotid , submandibular , and sublingual ) gland histopathology were performed using age - matched C3H / HeJ nonautoimmune
mice to control for
inflammation of nonautoimmune origin . -
pubmed
A significant increase in lacrimal gland
inflammation was found in the 5 month old C3H / Ipr autoimmune
mice in a histologic pattern similar to that of
Sjogren ' s syndrome in
human beings . -
pubmed
Sporadic
inflammation of the submandibular gland was seen in both autoimmune and control
mice , but this was neither statistically significant nor correlated with measures of
autoimmunity . -
pubmed
Sensitivity of cerebellar Purkinje neurons to neurotransmitters in genetically
epileptic rats . -
pubmed
We have conducted experiments using microiontophoresis with in situ extracellular recording of anesthetized
rat cerebellar Purkinje neuron activity to determine the sensitivity of these neurons to neurotransmitters in a genetic model of
epilepsy . -
pubmed
Current - response curves were generated and linear regression analysis was performed to evaluate changes in responsiveness and sensitivity between control and genetically
epilepsy - prone-9
rats . -
pubmed
The current required to produce 50 % inhibition of activity by
GABA was 2.6 - fold higher in the genetically
epilepsy - prone-9
rats compared to control . -
pubmed
We present a case report of a
patient with an isolated dissection of the subclavian artery after
blunt trauma . -
pubmed
The
patient who was admitted to our center after a
motor vehicle accident , complained of
chest and neck pain and physical findings of diminished left extremity
pulses . -
pubmed
The
porcine cauda equina would also be particularly suitable for chronic compression studies because any
neurologic deficit acquired would be restricted to the tail . -
pubmed
After curative resection of
colorectal cancer , immediate short - term postoperative intraportal adjuvant chemotherapy reduces the relative risk of recurrence and death in the non - transfused
patient significantly , when compared to transfused
patients without chemotherapy . -
pubmed
The transfused
patients with chemotherapy and those receiving neither transfusions nor chemotherapy had a relative risk of
recurrence and
death situated in between the two groups mentioned above , not statistically different from either of them . -
pubmed
[
Cardiac lipoma in a
patient with diffuse
subcutaneous lipomatosis . -
pubmed
We describe a case of
left ventricular intramyocardial lipoma in a
patient with diffuse
subcutaneous lipomatosis . -
pubmed
The four
strains of
E. - pubmed
Second bone marrow transplantation after
leukemia relapse in 11
patients . -
pubmed
Since June 1977 eight
patients with
acute leukemia and three with
chronic myelogenous leukemia (
CML ) have undergone cytoreductive therapy prior to a second allogeneic or syngeneic bone marrow transplantation ( BMT ) . -
pubmed
Of seven
patients who survived beyond 1 year , two
patients subsequently died , one as a result of acute
respiratory failure and one of
leukemia relapse . -
pubmed
In this
patient population which is at high risk for resistant disease and treatment - related
toxicity , a second preparative therapy and BMT may offer a durable disease remission with tolerable
toxicity . -
pubmed
Intracranial compliance , as estimated from a computerized frequency analysis of the intracranial pressure ( ICP ) waveform , was continuously monitored during the acute postinjury phase in 55
head - injured patients . -
pubmed
In 12
patients who developed uncontrollable
intracranial hypertension or clinical signs of
tentorial herniation during the monitoring period , 75 % were observed to have had an increase in the HFC to 9.0 Hz or more 1 to 36 hours prior to the clinical decompensation . -
pubmed
We performed clinical analysis of 12
patients with
renal cell carcinomas associated with
tumor thrombosis in the inferior vena cava . -
pubmed
Surgery could not be performed in the other 3
patients of their poor general condition or severe
heart disease . -
pubmed
One
patient died because of massive
hemorrhage during the operation . -
pubmed
In 4
patients without distant
metastases or regional lymph nodes
metastasis , two died of multiple
metastasis of
renal cell carcinomas and
diabetic coma . -
pubmed
Balb / c ( H-2d ) mice were transfused at weekly intervals with whole blood from donors of three
strains using two transfusion protocols . -
pubmed
Thoracolumbosacral laminectomy in
achondroplasia : long - term results in 22
patients . -
pubmed
Preoperatively , 91 % of
patients had motor function impairment , 86 % had
sensory dysfunction , 86 % had
neurogenic claudication , 77 % had
radicular pain , 59 % had symptomatic
bladder dysfunction , and 32 % had
fecal incontinence . -
pubmed
However , some
patients have , or later develop , compression adjacent to the myelographic site of
stenosis , and some develop
hypertrophic scarring at the site of initial decompression . -
pubmed
During the OGTT , the post -
glucose plasma
glucose values in the
diabetic patients were markedly higher ( P less than 0.001 ) than in the normal
subjects . -
pubmed
Late results of
epilepsy treatment in 150
children hospitalized in the Department of Psychiatry , Institute of Paediatrics , Medical Academy in Warsaw and followed - up in the outpatient clinic of this Department are described . -
pubmed
Physiological changes under elemental diet have been reported : decrease of gastric and pancreatic secretion , changes of
bacterial bowel flora and in patients with
Crohn ' s disease decreased fecal
bile acid excretion and decreased intestinal losses of lymphocytes were described . -
pubmed
Eight
infants with complex
cardiac anomalies and
pulmonary stenosis or
atresia were noted to have obstructed total anomalous pulmonary venous drainage ( TAPVD ) either at the initial cardiac catheterization ( Group 1 ; n = 2 ) or after creation of systemic - pulmonary artery shunts ( Group 2 ; n = 6 ) . -
pubmed
The 2
patients in Group 1 underwent early repair of
TAPVD ( 1 at 7 days , the other at 1 1/2 months of age ) before any subsequent operation and are now doing well at 18 months of age . -
pubmed
The 6
patients in Group 2 underwent repeat cardiac catheterization because of persistent severe
cyanosis with
faint or absent continuous murmur and were found to have patent shunts and obstructed
TAPVD ( 1 mild , 5 severe ) . -
pubmed
One patient who underwent repair of
TAPVD at 2 1/2 months of age survived and is well at 2 years of age , whereas 4
patients who underwent repair at an average age of 6 months ( age range , 3 - 16 months ) subsequently died . -
pubmed
[ Cytologic study of the cerebrospinal fluid in
leukemia patients with
neurologic symptoms ] . -
pubmed
[ Content and intensity of metabolism of free
nucleotides ,
nucleic acids , phosphoproteins and
phospholipids of the liver in experimental
atherosclerosis in
rabbits ] . -
pubmed
The
tumor promoter
phorbol myristic acetate (
PMA ) also enhances RNA synthesis and Ia antigen expression in B cells from both normal and CBA / N
mice . -
pubmed
I describe three
patients with
orthostatic tremor that involved mainly the legs and trunk and was not present when the
patients walked , sat , or lay down . -
pubmed
An enzyme - linked immunoassay ( ELISA ) was developed to study syngeneic humoral immune response to a primary
tumor and its
metastases in the K-1735 ultraviolet light ( UV)-induced C3H
murine melanoma system . -
pubmed
Binding of sera from syngeneic animals previously immunized with primary
tumor or metastatic
tumor tissue ( M-3 , M-4 ) to corresponding 3 M
KCl extracts of
tumor was significantly greater than binding of control C3H
mouse serum . -
pubmed
Antibody binding was not significantly reduced by competitive binding with syngeneic
murine muscle or liver extracts , indicating the presence of
tumor antigen(s ) not shared by normal
murine tissue . -
pubmed
Antibodies to the
tumor - associated antigens were selectively removed by competitive binding with syngeneic
K-1735 tumor extracts but not by the unrelated 102
murine sarcoma from
C57BL / 6 . -
pubmed
[ Role of nursing in the care of an
epileptic patient ] . -
pubmed
A 53 - year - old
man with a traumatic
dural arteriovenous fistula between the middle meningeal artery and the adjacent cortical vein is reported . -
pubmed
Fetal blood flow velocity waveforms of the middle cerebral artery were measured by pulsed Doppler ultrasound in 43 pregnant
women with
diabetes mellitus ( 33 class B , 3 class C , 6 class D and 1 class R ) . -
pubmed
DESIGN : We undertook a retrospective analysis on 396
patients with
chronic limb pain referred for autonomic testing during a 5 - year period . -
pubmed
Because certain physiologic trends occur in all
patients , general alterations of autonomic function with
pain are suggested . -
pubmed
( 1991 ) have reported that in our
mouse model system a membrane - associated 44 - kDa
acetaminophen - binding protein is the earliest target detected immunochemically following administration of an
hepatoxic dose of
APAP . -
pubmed
Thigmotaxis as an index of
anxiety in
mice . -
pubmed
We have considered the degree of thigmotaxis during this period of decrease as an index of
anxiety in
mice . -
pubmed
A retrospective analysis was performed of 48
patients with
hyperthyroidism ( 41
women aged 35 - 80 , mean 56.6 years ; 7
men aged 31 - 77 , mean 52.1 years ) treated with a fixed dose of 550 MBq 131I during a 12 month period May 1991 - April 1992 . -
pubmed
[
Nutrition disorders in fattening
pigs in an " organic " facility ] . -
pubmed
In a herd of fattening
pigs under an organic system of management , the following problems were observed :
sudden deaths ,
skin diseases ,
diarrhea , increased
restlessness and cannibalism . -
pubmed
The response of a
human tumor cell line to low radiation doses : evidence of enhanced sensitivity . -
pubmed
The survival of asynchronous , exponentially growing
DU-145 human tumor cells was measured after single doses of X rays in the dose range of 0.05 - 4 Gy using the cell sorting assay . -
pubmed
The efficacy rate of 2 - 4 g / day of
CDZM drip infusion against
infections was 53/56 ( 94.6 % ) while the
bacterial eradication rate was 36/38 ( 94.7 % ) . -
pubmed
Patients with a parenchymal
hemorrhage volume of 60 cm3 or more on their initial computed tomogram and a Glasgow Coma Scale score of 8 or less had a predicted 30 - day mortality of 91 % . -
pubmed
Only one of the 71
patients with a volume of parenchymal
hemorrhage of 30 cm3 or more could function independently at 30 days . -
pubmed
CONCLUSIONS : Volume of
intracerebral hemorrhage , in combination with the initial Glasgow Coma Scale score , is a powerful and easy - to - use predictor of 30 - day mortality and morbidity in
patients with spontaneous
intracerebral hemorrhage . -
pubmed
Ten
patients had on 2 occasions serum
calcium levels below or equal to 2 mmol / L and were defined as having severe
hypocalcemia . -
pubmed
Severe
hypocalcemia was found in 8
patients after total thyroidectomy , compared with 2 after hemithyroidectomy ( p & lt ; .05 ) , and was present in 3 of the 5
patients with
thyroid carcinoma , compared with 7 of the 90
patients with nonmalignant
thyroid diseases ( p & lt ; .01 ) . -
pubmed
No
patients had persistent symptoms of
hypocalcemia from 2 to 3 months after surgery . -
pubmed
Metabolic disorders of
cattle . -
pubmed
Goldberger discovered
human pellagra was a
non - infectious disease , affecting mostly the small and the timid in overcrowded institutions . -
pubmed
There is a diminished uptake of
glucose by the tissues , a condition also found in
parturient paresis of dairy
cows when elevated
hydrocortisone promotes
insulin resistance and
hyperglycaemia . -
pubmed
The major predisposing factor in
parturient paresis of dairy
cows is
hypocalcaemia . -
pubmed
[ Low - dose
midazolam reduces the
alfentanil demand in elderly but not in young
patients during extracorporeal
shock wave lithotripsy ] . -
pubmed
To evaluate whether
midazolam has analgesic properties in
humans after intravenous injection we studied the influence of a subhypnotic dose of
midazolam ( 50 micrograms / kg ) on the cumulative
alfentanil consumption in 53
patients during extracorporeal
shock wave lithotripsy ( ESWL ) using a
patient - controlled analgesia system ( PCAS ) . -
pubmed
Clinical and pathological features of
thoracic neoplasia in the
horse . -
pubmed
Thirty - eight
horses with confirmed
thoracic neoplasia included 28 ( 37.7 % ) with
lymphosarcoma , 4 ( 10.5 % ) with
metastatic renal cell carcinoma , 2 ( 5.3 % ) with
primary lung carcinoma , 2 ( 5.3 % ) with secondary
squamous cell carcinoma from the stomach , 1 ( 2.6 % ) with
pleural mesothelioma , and 1 ( 2.6 % ) with
malignant melanoma . -
pubmed
[ Effect of
propafenone hydrochloride on atrial signal - averaged ECG in
patients with
paroxysmal atrial fibrillation ] . -
pubmed
Oral
propafenone hydrochloride effect was studied on atrial signal - averaged ECG ( ASAECG ) during time- and frequency - domain analysis in
patients with
paroxysmal atrial fibrillation (
PAF ) during
ischemic heart disease (
IHD ) . -
pubmed
Our observation have indicated that oral
propafenone therapy does not influence any statistically significant differences all time- and frequency - domain parameters of ASAECG in
patients with
PAF during
IHD . -
pubmed
BACKGROUND : Cost - effective therapy that heals
ulcers rapidly and prevents
recurrence would significantly impact
patient care and the health system . -
pubmed
OBJECTIVE : To evaluate compression stockings for treatment of
venous ulcerations and prevention of recurrent ulceration ; to analyze
patient compliance ; and to evaluate cost of compression stocking therapy . -
pubmed
METHODS : Stocking therapy healed
venous ulcers in 53
patients . -
pubmed
RESULTS : Twenty - five
patients had good stocking usage ; one developed
recurrence ( 4 % ) . -
pubmed
Qualitative and quantitative characteristics of
chronic pain syndrome and their possible use in assessing analgetic effects of treatment were studied in 16 , 49 , 26 and 17
patients with
gastric ulcer ,
duodenal ulcer ,
chronic pancreatitis ,
chronic colitis , respectively . -
pubmed
These results suggest that
RA may be suitable for the treatment of
patients with
adult T cell leukemia (
ATL ) . -
pubmed
Human bite mark evidence is often found in violent crimes . -
pubmed
Patients with early - stage
tumors not requiring adjuvant radiation therapy attain long - term function comparable to that of patients who have had an IPAA for benign disease . -
pubmed
Exposure of
metronidazole - resistant ( MtzR )
strains of
H. - pubmed
PURPOSE : To evaluate the technical possibility of creating a percutaneous retroperitoneal splenorenal shunt ( PRESS ) in
swine as a minimally invasive treatment of
portal hypertension . -
pubmed
Finally , the use of inhaled
corticosteroids results in the control of
asthma , allowing
patients to exercise , which itself improves bone density and protects against
osteoporosis . -
pubmed
We studied saccade and smooth pursuit eye movements in 31
patients suffering from
myotonic dystrophy (
MD ) . -
pubmed
Since D5 / D35 dissociation occurred in 26/33
multiple sclerosis patients with increased saccade duration , we considered it to be a neurogenic pattern attributable to a
central nervous system ( CNS ) dysfunction . -
pubmed
Accordingly we classified the
oculomotor abnormalities detected as neurogenic in 11
MD patients and as myogenic in another 10 , but in some subjects belonging to the second group concomitant
CNS impairment is not to be excluded . -
pubmed
We evaluated 138 relatively unselected
patients with
peripheral neuropathy who underwent neurologic evaluation , electromyography ( EMG ) , nerve conduction studies , and autonomic function tests to determine which variables were predictive of laboratory findings of
autonomic failure . -
pubmed
We conclude that autonomic studies will most likely be abnormal in
patients who have symptoms of autonomic involvement and those who have an
axonal neuropathy . -
pubmed
All
animals were re - explored 14 days later , and the abdominal cavity was examined for
adhesions . -
pubmed
DOCA - salt
hypertension was induced in 8 - wk - old male
Wistar rats by uninephrectomy and administration of
DOCA ( 25 mg every fourth day , subcutaneously ) and 1 %
NaCl in the drinking water for 4 wk . -
pubmed
The objective of this work was to explore if an interaction with beta - blocker treatment plays a role in the decrease of
cardiac arrhythmic deaths with
amiodarone in
patients recovered from an
acute myocardial infarction . -
pubmed
Unadjusted and adjusted relative risks for all - cause mortality ,
cardiac death ,
arrhythmic cardiac death ,
nonarrhythmic cardiac death ,
arrhythmic death , or resuscitated
cardiac arrest were lower for
patients receiving beta - blockers and
amiodarone than for those without beta - blockers , with or without
amiodarone . -
pubmed
Interrelation between cerebral energy metabolism and behaviour in a
rat model of permanent
brain vessel occlusion . -
pubmed
The data of the present study demonstrate a linear relationship between cerebral energy metabolism and brain memory capacities after acute and permanent
vessel occlusions in
rats . -
pubmed
RESULTS : During the prospective six - month phase , 84 confirmed
stroke patients were transported to the target hospitals . -
pubmed
Induction of
hyperplasia and increased DNA content in the uterus of immature
rats exposed to
coumestrol . -
pubmed
In addition ,
bromodeoxyuridine staining of uterine sections enabled confirmation of
uterine hyperplasia for the
coumestrol - treated
animals . -
pubmed
INTERVENTIONS : Empiric dosing for both groups was based on
patient - specific pharmacokinetics and severity of
infection . -
pubmed
MEASUREMENTS AND MAIN RESULTS :
Nephrotoxicity occurred in 7.5 %
patients treated with
ODA and 14.7 % receiving
TDA ( p=0.05 ) . -
pubmed
CONCLUSION : The trend was toward decreased
nephrotoxicity in
patients treated with
ODA compared with
TDA , and at any given cumulative AUC , the risk of toxicity was lower for
ODA . -
pubmed
Automated classification of
human atrial fibrillation from intraatrial electrograms . -
pubmed
Different
ofloxacin - loaded unilamellar vesicles were prepared by the extrusion technique , and their antimicrobial activities were determined in comparison to those of the free drug by means of MIC determinations with both American Type Culture Collection standards and wild - type bacterial
strains ( six
strains of
Enterococcus faecalis , seven
strains of
Escherichia coli , six
strains of
Staphylococcus aureus , and six
strains of
Pseudomonas aeruginosa ) . -
pubmed
Relevant prevalence of
Mycoplasma hominis and
Ureaplasma urealyticum serogroups in
HIV-1 infected men without
urethritis symptoms . -
pubmed
urealyticum are the better - known mycoplasma species pathogenic to the
human genitourinary tract , causing mainly
urethritis ,
bacterial vaginosis and
pregnancy complications . -
pubmed
The aim of this work was to determinate the prevalence of these species in this group of male patients (
HIV group ) , in comparison to a group of men with clinical symptoms of
urethritis (
STD group ) . -
pubmed
In the
STD group these rates were 0.9 % ( 1/110 ) for
M. - pubmed
A
pneumococcal conjugate vaccine and
acute otitis media . -
pubmed
The effect of denervation or acute
insulin deficiency on brown adipose tissue lipogenesis was investigated in
rats adapted to a high - protein diet before and after diet reversion to a balanced diet . -
pubmed
This review outlines the current state of knowledge of
cerebral disease in
humans , and discusses the contribution of studies of animal models to elucidation of the underlying mechanisms . -
pubmed
Besides this difficulty in differentiation , a well - used medical school textbook of microbiology , Atlas , points out that even among experts , different observers may classify the same
strain of bacteria as Nocardia or
Mycobacterium tuberculosis . -
pubmed
The therapeutic effect of
PEPM - Cre plus
CMV - lox - TK was also observed in xenografted
LNCaP cells on
nude mice when the plasmids were directly injected into
tumors and
GCV was administered intraperitoneally . -
pubmed
Biopsy specimens were obtained from back skins treated with topical
anthralin or white
petrolatum ( control ) in 4
patients with
psoriasis vulgaris . -
pubmed
We report on the
death of a 22 - year - old
man after the ingestion of
ecstasy pills containing
PMMA and
PMA . -
pubmed
BACKGROUND :
Patients with
lipodermatosclerosis (
LDS ) due to
chronic venous disease (
CVD ) of the lower limb show proliferation and convolution of their skin capillaries . -
pubmed
Ten control
subjects with no arterial or
venous disease of the lower limb were also studied . -
pubmed
In
patients with skin changes the most severe regions of
LDS were studied . -
pubmed
CONCLUSIONS : Amongst
patients with
venous disease , capillary convolution is strongly associated with the more severe stages (
LDS and healed
ulceration ) , which can reliably be reproduced by capillary microscope . -
pubmed
BACKGROUND : Most reports on
basilar artery ( BA ) occlusive disease have retrospectively described single cases or small
patient series . -
pubmed
OBJECTIVE : To assess clinical and vascular features ,
stroke mechanisms , etiologies , and outcome of moderate to severe
BA occlusive disease among 407
patients in the New England Medical Center Posterior Circulation Registry , the largest prospective series of consecutively collected
patients with
posterior circulation ischemia to date . -
pubmed
RESULTS : We studied 87
patients and identified 3
patient groups with distinct vascular , clinical , etiological , and prognostic characteristics : isolated
BA disease ( 39 patients [ 44.8 % ] ) , BA involvement as part of widespread posterior circulation
atherosclerosis ( 36 patients [ 41.4 % ] ) , and
embolism to the BA ( 12 patients [ 13.8 % ] ) . -
pubmed
Fifty - eight
patients ( 66 % ) initially had
transient ischemic attacks , of whom 34 ( 58.6 % ) progressed to
stroke . -
pubmed
Outcome was best among
patients with widespread
atherosclerotic disease and worst in 7 ; ( 58.3 % , with major disability ) of 12
patients with
embolism to the BA . -
pubmed
METHODS : Forty - four
patients with advanced
gastrointestinal cancer ( 25 gastric and 19
colorectal cancer ) and 25 healthy controls were enrolled . -
pubmed
These changes may be correlated with hibernation arrest and
death of treated
jerboa . -
pubmed
[ Establishment and judgement of the
animal model of focal
ischemia - reperfusion ] . -
pubmed
OBJECTIVE : To investigate the influence of reperfusion after
ischemia for 90 , 120 , 180 minutes on the focal
ischemia reperfusion
animal model . -
pubmed
METHODS : The string - fastening method was used to establish focal
ischemia - reperfusion models in SD
rats and the
rats were divided into 4 groups :
ischemia - reperfusion for 90 , 120 and 180 minute groups and the sham operation group . -
pubmed
CONCLUSION :
Cerebral ischemia for 120 minutes is ideal for establishing the
animal model . -
pubmed
We have developed in vitro and in vivo
animal models to study mechanisms of acquired
peripheral neuropathies and used these models to evaluate the therapeutic potential of novel compounds . -
pubmed
Subcutaneously implanted
human A431 epidermoid
carcinoma and
U251 glioblastoma cells served as
tumor models . -
pubmed
Although
tumor ( 18 ) F - FDG uptake was not above background activity under the reference condition ,
tumors demonstrated marked focal
( 18 ) F - FDG uptake in warmed and fasted
animals . -
pubmed
CONCLUSION :
Animal handling has a dramatic effect on
( 18 ) F - FDG biodistribution and significantly influences the results of microPET studies in
tumor - bearing
mice . -
pubmed
To improve
tumor visualization
mice should be fasted and warmed before
( 18 ) F - FDG injection and during the uptake period . -
pubmed
Isoflurane appears well suited for anesthesia of
tumor - bearing
mice , whereas
ketamine / xylazine should be used with caution , as it may induce marked
hyperglycemia . -
pubmed
METHODS : This was a retrospective , noninterventional case series of 11
patients with
FES . -
pubmed
Five
patients had a known diagnosis of
OSA . -
pubmed
Pelibuey
sheep ( 60 % , 6 of 10 ) ovulated continuously during the entire study ; one animal was eliminated in the second year , due to ovarian
follicular cysts and three ewes had anestrous periods from 65+/-46 to 70+/-36 days . -
pubmed
The
body weight of
Pelibuey ewes was constant during the entire study and was not correlated with ovulatory activity . -
pubmed
A study to standardize quantitative evaluation of parotid gland scintigraphy in
patients with
Sjogren ' s syndrome . -
pubmed
METHODS : Forty - five
patients with
SS and 23 controls were studied . -
pubmed
RESULTS : The levels of peak count , uptake speed , and excretion speed in the
patients with
SS were significantly lower than the levels in the controls , whereas there was no significant difference of excretion fraction level between the
patients with
SS and the controls . -
pubmed
Different effects of high molecular weight
sodium hyaluronate and NSAID on the progression of the
cartilage degeneration in
rabbit OA model . -
pubmed
OBJECTIVE : We examined the effects of nonsteroidal anti - inflammatory drug ( NSAID ) and intra - articular injections of
sodium hyaluronate ( HA ) on
cartilage degeneration in
rabbit knee osteoarthritis (
OA ) model induced by partial meniscectomy . -
pubmed
Breathing
He /
O2 can benefit
critically ill patients with severe respiratory compromise mainly by reducing airway resistance in obstructive
syndromes such as acute
asthma and decompensated
chronic obstructive pulmonary disease . -
pubmed
The potential use of
variola virus , the causative agent of
smallpox , as a bioweapon and the endemic presence of
monkeypox virus in Africa demonstrate the need for better therapies for
orthopoxvirus infections . -
pubmed
Correlation between radial artery tonometry- and fingertip tonometry - derived augmentation index in
children with
type 1 diabetes . -
pubmed
Preparations containing
isoflavones in variable doses , such as soy extract and
red clover , or extracts from evening primrose ,
Cimifuga racemosa ,
ginseng and
black cohosh are often used for treating the
climacteric syndrome . -
pubmed
Loss of penile length following penile implantation surgery is worrisome for
patients suffering from
erectile dysfunction (
ED ) . -
pubmed
Infection by
ToMV and feeding damage by
H. - pubmed
Overall , this study indicated that , in general , insect damage has a stronger effect than
ToMV infection on plant chemistry and , subsequently , on the performance of
H. - pubmed
The predominant comorbidities were previous
myocardial infarction in 71.4 % of the
patients ,
diabetes mellitus in 34.2 % , and
renal failure in 14.2 % . -
pubmed
No cases of
sternal dehiscence or
infection were observed , but one
patient suffered a
stroke on the fourth postoperative day and died . -
pubmed
No late
deaths occurred , 31
patients are asymptomatic , and three have residual
angina . -
pubmed
A randomized Phase III study was started in Japan to demonstrate the non - inferiority of survival of accelerated fractionation radiation therapy ( 2.4 Gy / fr ) with conventional fractionation radiation therapy ( 2 Gy / fr ) in
patients with
T1 - 2N0M0 glottic cancer . -
pubmed
METHODS : Thirty - two
patients with
parotid gland malignancy underwent
tumor and parotid gland excision while preserving facial never . -
pubmed
The
patients were followed up after operation and the local
tumor control and facial nerve function were observed . -
pubmed
RESULTS :
Tumor recurrence was not found in any
patient treated after 12 to 44 months of follow up . -
pubmed
We evaluated data from 390
patients ( 406 ankles ) who consulted our center because of painful end - stage
ankle osteoarthritis (
OA ) by using medical history , physical examination , and radiography . -
pubmed
Patients with posttraumatic end - stage
ankle OA were younger than patients with primary
OA . -
pubmed
Cellular and molecular characterization of these cells revealed many similarities to
human embryonic stem cells , and the germline stem cells produced
teratomas after transplantation into
immunodeficient mice . -
pubmed
PATIENT(S ): Nineteen
patients with
PCOS and 21 controls . -
pubmed
Nasal
steroids helpful for short - term treatment of
children with
obstructive sleep apnea . -
pubmed
In this paper , we present a series of 8 consecutive
patients with
diaphragmatic anomalies who underwent robotic repair . -
pubmed
METHODS : We retrospectively reviewed
patients with
diaphragmatic anomalies . -
pubmed
There were 2
patients with eventration , 5 with
B - CDH , and 1 with
M - CDH . -
pubmed
CONCLUSIONS : Robotic surgery is safe and effective for repairing
diaphragm anomalies in small
children . -
pubmed
Indications for the procedure were the evaluation of suspected
inflammatory bowel disease in eight
patients and evaluation of
protein - losing enteropathy in one patient . -
pubmed
We compared DNA damage and the efficacy of its repair after genotoxic treatment with gamma - radiation of lymphocytes and tissue cells isolated from
patients with
squamous cell carcinoma of head and neck (
HNSCC ) and healthy donors . -
pubmed
We conclude that gamma - radiation might be considered as an effective therapeutic strategy for
head and neck cancers , including
patients in advanced stage of the disease with clear evidence of
metastasis . -
pubmed
Cord blood transplantation with a reduced - intensity conditioning regimen for
patients with relapsed aggressive
multiple myeloma after cytoreduction with
bortezomib . -
pubmed
Two
multiple myeloma patients relapsed after autologous stem cell transplantation ( ASCT ) . -
pubmed
The second
patient developed acute and chronic
GVHD , and both responded to the
steroid therapy . -
pubmed
As biochemical and molecular
cobalt - induced toxicological mechanisms are not fully identified , we investigated
cobalt toxicity in a model
human keratinocyte cell line ,
HaCaT. -
pubmed
Genetic counseling and risk assessment depend on determination of the specific cause of an
inherited ataxia in an
individual . -
pubmed
RESULTS : Of the 582 included
women , 76 developed
ESRD 3.9 + - 3.4 years ( range , 0.08 - 16 years ) after diagnosis . -
pubmed
Here , we report our experience on three
patients with
AMR who were treated with
bortezomib after other therapeutic interventions had failed . -
pubmed
The third
patient developed worsening
thrombocytopenia following the second dose . -
pubmed
CLINICAL PRESENTATION : Two
patients , age 44 and 60 years , presented with Hunt and Hess grade 3
subarachnoid hemorrhage from
aneurysmal rupture . -
pubmed
A double - blind , placebo - controlled comparison of
letrozole to
oxandrolone effects upon growth and puberty of
children with
constitutional delay of puberty and
idiopathic short stature . -
pubmed
METHODS : In a prospective , double - blind , randomized , placebo - controlled clinical trial , 91
CDGP boys ( 12.6 - 14.6 years old ) with predicted
short stature were treated with
letrozole ( 2.5 mg / day ) ,
oxandrolone ( 2.5 mg / day ) , or placebo , at the outpatient pediatric endocrine clinic of Mofid
Children 's Hospital in Tehran for 2 years . -
pubmed
CONCLUSION : This first randomized controlled clinical trial in
CDGD teenage
boys with predicted
short stature shows that
letrozole increases
PAH more than
oxandrolone and advances pubertal stage and bone mineralization less . -
pubmed
METHODS : The
BSR cell was infected by triple serial dilution of the
Rabies Virus CTN
strain , then detect the fluorescent focus by
FITC labeling anti -
Rabies Virus monoclonal antibodies . -
pubmed
ABSTRACT :
Synaptic dysfunction is widely thought to be a pathogenic precursor to neurodegeneration in
Alzheimer ' s disease (
AD ) , and the extent of
synaptic loss provides the best correlate for the severity of
dementia in
AD patients . -
pubmed
Influence of 5 - HTTLPR polymorphism on resting state perfusion in
patients with
major depression . -
pubmed
MDD patients were stratified according to receptor polymorphism , both using a bi - allelic ( group A : L / L vs. group B : S / S and S / L genotype ) and a tri - allelic approach ( Group A ' : LA / LA vs. Group B ' : non - LA / LA genotype ) . -
pubmed
We demonstrate that in
patients with
MDD , 5 - HTTLPR gene polymorphism modulates resting state perfusion in key structures of mood processing . -
pubmed
Collagen - induced
arthritis in common
marmosets : a new
nonhuman primate model for
chronic arthritis . -
pubmed
INTRODUCTION : There is an ever - increasing need for
animal models to evaluate efficacy and safety of new therapeutics in the field of
rheumatoid arthritis (
RA ) . -
pubmed
In response to this requirement we set out to develop a model of collagen - induced
arthritis (
CIA ) in a small - sized nonhuman
primate species ( 300 to 400 g at adult age ) ; that is , the common
marmoset (
Callithrix jacchus ) . -
pubmed
RESULTS : Clinically manifest
arthritis was observed in almost 100 % ( 21 out of 22 ) of the
animals . -
pubmed
Fifty percent of the
animals developed semi - acute
CIA while the other 50 % displayed a more
chronic disease . -
pubmed
CONCLUSIONS : This new model in
marmosets more closely resembles chronic
RA with respect to the
chronic disease course and pathomorphological presentation than the more acute monophasic and destructive
CIA model in
macaques . -
pubmed
Differential mucosal expression of Th17 - related genes between the inflamed colon and ileum of
patients with
inflammatory bowel disease . -
pubmed
In the present study , the
cytotoxic effect of a new
flavonoid ,
2 -( cis-1 , 2 - dihydroxy 4 - oxo - cyclohex-5 - enyl )- 5 , 7 - dihydroxy - chromone (
DEDC ) , which is a
protoapigenone analog , was investigated in
human hepatoma HepG2 cells . -
pubmed
Feasibility study of the
zebrafish assay as an alternative method to screen for
developmental toxicity and
embryotoxicity using a training set of 27 compounds . -
pubmed
To anticipate to increased testing needs for
reproductive toxicity and 3R approaches , we studied
zebrafish embryo / larva as an alternative for
animal testing for
developmental toxicity and
embryotoxicity and evaluated a training set of 27 compounds with a standardized protocol . -
pubmed
Efficacy of second - generation antihistamines in
patients with
allergic rhinitis and comorbid
asthma . -
pubmed
Clinical trials were included that reported results for
patients with
AR and comorbid
asthma who were treated with second - generation antihistamines . -
pubmed
Mechanistic and clinical data suggest that the potential of H1 - antihistamines to alleviate comorbid
asthma symptoms in
AR patients should be further investigated . -
pubmed
Diphtheria ,
pertussis (
whooping cough ) , and
tetanus vaccine induced recurrent
seizures and acute
encephalopathy in a pediatric
patient : Possibly due to pertussis fraction . -
pubmed
Recommendations for management of
patients with
carotid stenosis . -
pubmed
This paper will highlight the complexities of decision - making optimal treatment recommendations for
patients with symptomatic and asymptomatic
carotid stenosis . -
pubmed
This is the first reported case in which
parotid tumour was the presenting complaint of the
patient . -
pubmed
Thirty - nine
RCC patients were selected for 3 - year disease - free survival analysis . -
pubmed
Patients had been classified at baseline as tremordominant or
akinetic - rigid according to a "
tremor score " and " non -
tremor score " . -
pubmed
At follow - up ,
akinetic - rigid
patients showed a distinct and statistically significant reduction of the dopaminergic uptake associated with significant progression of the clinical symptoms ( UPDRS III ) . -
pubmed
In contrast , in
tremor patients the aggravation of clinical symptoms and
dopaminergic deficit was less pronounced without statistical significance among assessments . -
pubmed
CONCLUSIONS : This study shows for the first time a considerable progression of clinical symptoms and in - vivo dopaminergic deficit of
akinetic - rigid compared to tremordominant
PD patients over time . -
pubmed
Multislice computed tomography to rule out
coronary allograft vasculopathy in heart transplant
patients . -
pubmed
BACKGROUND : This study assessed if invasive coronary angiogram ( CA ) could be replaced by multislice ( 64- or 256 - row ) computed tomography ( MSCT ) to systematically rule out
coronary allograft vasculopathy in heart transplant
patients . -
pubmed
CONCLUSION : Newer generations of MSCT ( 64- or 256 - row ) have a good NPV and may represent an alternative to invasive CA to rule out significant ( & gt;50 % )
coronary vasculopathy in heart transplant
patients , despite a low PPV . -
pubmed
In 60 % of the
patients , this
congenital lesion presents bilaterally . -
pubmed
As IHAE scientists assessed
human performance and adaptation to
hypoxia , low barometric pressure , and cold , they not only illuminated the physiological and psychological processes of high altitude acclimatization , but they also drew borderlines between the normal and the pathological , paved the way for the neocolonial exploitation of natural and
human resources in Latin America , and pioneered field methods in physiology that were adapted and adopted by the Allied Forces during the Second World War . -
pubmed
BACKGROUND AND PURPOSE : Despite appropriate radiotherapy , high - risk
prostate cancer patients often experience local relapse and progression to metastatic disease . -
pubmed
In vivo ,
BEZ235 pretreatment enhanced the efficacy of radiation therapy on
PC3 xenograft
tumors in
mice without inducing intestinal
radiotoxicity . -
pubmed
Drug screening using a library of
human induced pluripotent stem cell - derived cardiomyocytes reveals disease - specific patterns of
cardiotoxicity . -
pubmed
BACKGROUND :
Cardiotoxicity is a leading cause for drug attrition during pharmaceutical development and has resulted in numerous preventable
patient deaths . -
pubmed
Here we generated a library of
human induced pluripotent stem cell - derived cardiomyocytes ( hiPSC - CMs ) from
patients with various hereditary
cardiac disorders to model differences in
cardiac drug toxicity susceptibility for
patients of different genetic backgrounds . -
pubmed
METHODS AND RESULTS : Action potential duration and drug - induced
arrhythmia were measured at the single cell level in hiPSC - CMs derived from healthy
subjects and
patients with
hereditary long QT syndrome ,
familial hypertrophic cardiomyopathy , and
familial dilated cardiomyopathy . -
pubmed
CONCLUSIONS : We have recapitulated drug - induced
cardiotoxicity profiles for healthy
subjects ,
long QT syndrome ,
hypertrophic cardiomyopathy , and
dilated cardiomyopathy patients at the single cell level for the first time . -
pubmed
Our data indicate that healthy and diseased
individuals exhibit different susceptibilities to
cardiotoxic drugs and that use of disease - specific hiPSC - CMs may predict adverse drug responses more accurately than the standard
human ether - a - go - go - related gene test or healthy control hiPSC - CM / hESC - CM screening assays . -
pubmed
Self - correction of
chromosomal abnormalities in
human preimplantation embryos and embryonic stem cells . -
pubmed
This review addresses
aneuploidies in
human preimplantation embryos and
human ESCs and the potential of self - correction of these aberrations . -
pubmed
OBJECTIVE : To describe the behavior and characteristics of
GERD in
patients with recurrent
laryngitis . -
pubmed
MATERIAL AND METHODS : This is a retrospective study involving pediatric
patients with recurrent
laryngitis ( 2 or more episodes in 6 months ) referred for study of possible
GERD . -
pubmed
CONCLUSION : There is a significant percentage of
patients with normal 24 hour Ph monitoring that had not been diagnosed with
GERD without
IIM . -
pubmed
OBJECTIVE : The aim of this study was to analyze and compare the clinicopathologic characteristics , treatment , and survival in
patients with
uterine leiomyosarcoma (
ULMS ) during the last 10 years in 3 referral academic centers . -
pubmed
METHODS : All
patients with
ULMS who underwent treatment at the participating institutions between January 1 , 2000 , and December 31 , 2010 , were identified from the
tumor registry database . -
pubmed
RESULTS : Analysis of 167
women with
ULMS with adequate follow - up was performed . -
pubmed
Metformin for
weight loss and metabolic control in
overweight outpatients with
schizophrenia and
schizoaffective disorder . -
pubmed
OBJECTIVE : The purpose of this study was to determine whether
metformin promotes
weight loss in
overweight outpatients with
chronic schizophrenia or
schizoaffective disorder . -
pubmed
METHOD : In a double - blind study , 148 clinically stable ,
overweight (
body mass index [
BMI ] & gt;=27 )
outpatients with
chronic schizophrenia or
schizoaffective disorder were randomly assigned to receive 16 weeks of
metformin or placebo . -
pubmed
CONCLUSIONS :
Metformin was modestly effective in reducing weight and other risk factors for
cardiovascular disease in clinically stable ,
overweight outpatients with
chronic schizophrenia or
schizoaffective disorder over 16 weeks . -
pubmed
Metformin may have an important role in diminishing the adverse consequences of
obesity and
metabolic impairments in
patients with
schizophrenia . -
pubmed
Surgical management of
patients with
bowel obstructions secondary to
gastric cancer . -
pubmed
METHODS : The medical records of all of the
patients who were admitted for an
intestinal obstruction after curative resection for
gastric cancer were retrospectively reviewed . -
pubmed
The
patients were divided into 2 groups :
patients with no evidence of a
tumor recurrence and
patients with evidence of a
tumor recurrence . -
pubmed
Open and close surgery was the main type of surgical procedure reported for the
patients with
tumor recurrences . -
pubmed
The consequence of
strawberries coating , with antifungal composite based solution , was the disappearance of gray mold
infection signs in 90 % of the contaminated fruits after 7 d of storage , treated fruits had a fresh - like appearance at the end of storage . -
pubmed
Use of
111In - pentetreotide scan in a
subject with treatment refractory atypical
meningioma . -
pubmed
The
patient remained symptomatic with intermittent severe
headaches associated with
nausea ,
vomiting , and
visual disturbance . -
pubmed
Univariate and multivariate random effects negative binomial regressions were used to predict risk factors for child
malaria incidence and the mean total number of indoor female
Anopheles gambiae and funestus mosquitoes collected per household across three occasions . -
pubmed
Multivariate regressions showed that residing in rural areas ( versus urban ) increased
malaria incidence rates by over three - fold and mean indoor female
A. - pubmed
Ischemia - reperfusion is a major determinant of
myocardial impairment in
patients undergoing cardiac surgery . -
pubmed
First described in
animals in 1986 , myocardial ischemic conditioning consists of applying increased tolerance of the myocardium to sustained
ischemia by exposing it to brief episodes of
ischemia - reperfusion . -
pubmed
Tongue diagnosis system for quantitative assessment of tongue coating in
patients with
functional dyspepsia : a clinical trial . -
pubmed
MATERIALS AND METHODS : The present study was designed as a prospective clinical trial including 60
patients with
functional dyspepsia . -
pubmed
Here we describe the design of GIFM experiments in adult
mice as exemplified by CreER(T2)-assisted tracing of vascular smooth muscle cells during the development of
atherosclerotic lesions . -
pubmed
Recurrent hospital admission rates with exacerbation of
obstructive pulmonary disease were higher in the illicit drug smokers compared with current / ex -
tobacco smokers ( 1.00 versus 0.22/0.26 , p & lt ; 0.001 ) . -
pubmed
Many strategies have been evaluated over the past 15 years but none of these approaches has resulted in improved survival rates for
patients with
SCLC . -
pubmed
Specifically , the article discusses ganitumab and its applicability to
SCLC patients . -
pubmed
EXPERT OPINION : At present , there is a lack of therapeutic choices for
patients with advanced
SCLC . -
pubmed
Unfortunately , ganitumab , administered in combination with chemotherapy , demonstrated no clinical activity in
patients with
SCLC , although it could have utility with other
cancers . -
pubmed
Fungal melanonychia caused by
Trichophyton rubrum and the value of dermoscopy . -
pubmed
METHODS : In a prospective and multicenter study ,
children with suspected
peanut or hazelnut allergy underwent oral challenges . -
pubmed
RESULTS : Among 563 screened
patients , 75 ( 13.3 % ) were
Her2 positive ( IHC 2+/3 + and FISH+ ) and 61 met all eligibility criteria ( median age , 64 years ; 54/61
males ; 50/61 baseline ECOG - PS 0 - 1 ; 11 locally advanced and 50 metastatic ) . -
pubmed
These data indicate that multiple mechanisms contribute to the rare , but potentially severe
liver injury caused by
sitaxentan in
humans ; provide a plausible rationale for the markedly lower propensity of
bosentan to cause
liver injury ; and highlight the relative safety of
ambrisentan . -
pubmed
The tsetse fly vector transmits the protozoan
Trypanosoma brucei , responsible for
Human African
Trypanosomiasis , one of the most neglected
tropical diseases . -
pubmed
Patients presenting with
nephritic syndrome tend to be
hypertensive with dipstick - positive or visible
haematuria . -
pubmed
All
patients with
glomerulonephritis should be managed according to
CKD guidelines with
CKD stage - appropriate measurement of renal function , blood pressure , and
proteinuria . -
pubmed
Six
patients had scapholunate joint widening , one had windshield - wipering of the screws with loss of reduction , and two demonstrated progression of scapholunate advanced collapse
deformity . -
pubmed
Patients who underwent elective operations that involved long
wound closure were enrolled in the study . -
pubmed
Each
patient acted as their own internal control with half their
wound being sutured with 3/0 V - Loc 180 barbed suture and the other half with smooth 3/0 Maxon deep dermal sutures and then a subcuticular skin closure . -
pubmed
RESULTS : The false - positive rate for AA among 413 VLBW
infants was significantly higher than infants with
birth weight & gt;1500 g ( 7.62 % vs 0.05 % ; P & lt ; .001 ) . -
pubmed
METHODS : In total , 102 consecutive
patients with
hip fracture over the age of 65 were admitted to the orthopedic unit and prospectively evaluated . -
pubmed
All of the
patients were treated according to specific protocols depending on the type of
fracture . -
pubmed
Among these
patients , 73 % were female , and 37 % had
vitamin D deficiency . -
pubmed
The median LOS was 7 ( 5 - 11 ) d.
Patients with
vitamin D deficiency had lower handgrip strength in univariate analysis . -
pubmed
RESULTS : In the time period , 1939 children were hospitalized due to
varicella infection in Turkey ; 36
children ( 20
boys , 16
girls , mean age 68.0 + 37.6 months , all received single dose live
varicella vaccine ) with breakthrough
varicella infection . -
pubmed
METHODS : We retrospectively reviewed the clinical and pathological files of
patients having undergone EBUS - TBNA from February 2011 to October 2014 to investigate
thoracic lesions . -
pubmed
Among 736
patients , we identified four of them with a diagnosis of
MPM achieved primarily through EBUS - TBNA . -
pubmed
RESULTS : In all
patients , the collected tissue was adequate , and the histological analysis in association with immunohistochemistry led us to the diagnosis of
malignant pleural mesothelioma . -
pubmed
In three
patients , the diagnosis of
mesothelioma was clinically suspected , as patients presented with diffuse pleural thickening . -
pubmed
In two
patients , videothoracoscopy was not possible owing to the ' dry ' presentation of the
pleural disease and the site of thickening . -
pubmed
OBJECTIVE : Transcatheter aortic valve implantation ( TAVI ) is an alternative treatment for
patients with severe symptomatic
aortic stenosis , inoperable or at high surgical risk . -
pubmed
METHODS : Review of 17
patients data with symptomatic severe
aortic stenosis at high surgical risk or inoperable , treated with a transcatheter implantation aortic valve ( TAVI ) via femoral surgical access with Core Valve ( Medtronic , EE.UU . ) -
pubmed
RESULTS : All
patients had severe
aortic stenosis with a mean gradient of 46ae14 mmHg received CoreValveTM ( Medtronic , USA ) . -
pubmed
One
patient complicated with
acute renal failure , 2 had in - hospital
ischemic stroke ( 11.7 % ) , none had need for cardiac surgery ; 2 patients had major
bleeding complications that required transfusion . -
pubmed
We provide a perspective on our experience with
human and
murine Treg suppression assay conditions , including Treg data obtained in clinical transplant studies , Tregs isolated from healthy donors and treated with epigenetically active compounds , and Tregs from standard
murine strains ( C57BL/6 and BALB / c ) . -
pubmed
The
patient had microvascular complications of
diabetes . -
pubmed
Precise targeting of genetic lesions alone has been insufficient to extend
brain tumor patient survival . -
pubmed
RESULTS A total of 133 lasers were placed in 102
patients who required intervention for
intracranial tumors ( 87
patients ) ,
chronic pain syndrome ( cingulotomy , 5
patients ) , or
epilepsy ( 10
patients ) . -
pubmed
Ninety - two
patients ( 90.2 % ) had undergone previous treatment for their
intracranial tumors . -
pubmed
For some members of this group , antiviral activity was also found against
human cytomegalovirus ,
hepatitis B , norovirus , and
measles . -
pubmed
The purpose of this study is to demonstrate , using multivariate analysis of preoperative and intraoperative
patient characteristics to determine risk factors for negative outcomes , that
PD can be performed safely in the elderly . -
pubmed
RESULTS :
Death occurred in one
patient ( 2.3 % ) in group A. -
pubmed
BACKGROUND AND AIMS : Although endoscopic ultrasound ( EUS ) is used in the management of various
gastrointestinal ( GI ) diseases in adults , data on its role in
children is limited . -
pubmed
EUS diagnosed chronic
pancreatitis ( 21
patients ) ,
pancreatic necrosis ( 1 ) ,
splenic artery pseudoaneurysm ( 1 ) ,
gastric varix ( 1 ) ,
pseudocysts ( 3 ) ,
insulinomas ( 2 ) , other
pancreatic masses ( 2 ) ,
choledocholithiasis ( 2 ) ,
choledochal cysts ( 2 ) ,
portal biliopathy ( 1 ) ,
esophageal leiomyoma ( 1 ) ,
gastric neuroendocrine tumor (
NET ) ( 1 ) , and
GI stromal tumor in stomach ( 1 ) . -
pubmed
EUS - guided FNAC was positive in four of seven
patients ( two had
tuberculosis , one
pancreatic solid pseudopapillary tumor , and one
gastric NET ) . -
pubmed
MATERIAL AND METHODS : Forty - five
patients with
chronic periodontitis and 45 periodontally healthy
patients were included in this case - control study . -
pubmed
We report a case of a 60 - year - old
man diagnosed with
papillary thyroid cancer who had a
relapse seen only in the brain at
FDG PET on standard images . -
pubmed
Perfusion cardiovascular magnetic resonance and fractional flow reserve in
patients with angiographic multi - vessel
coronary artery disease . -
pubmed
METHODS AND RESULTS : Forty - one
patients ( 123 vascular territories ) with angiographic 2- or 3 - vessel
coronary artery disease (
visual stenosis & gt;50 % ) underwent high - resolution
adenosine stress perfusion CMR at 1.5 T and FFR measurement . -
pubmed
Validation and optimization of a predictive model for
radiation pneumonitis in
patients with
lung cancer . -
pubmed
Consecutive
patients with
non - small cell lung carcinoma (
NSCLC ; n=71 ) treated with definitive concurrent chemotherapy and radiotherapy were retrospectively assessed for
radiation pneumonitis (
RP ) . -
pubmed
The Effectiveness of Mental Practice : With Motor Imagery in the Neurological Rehabilitation of
Stroke Patients * for the improvement of UE function . -
pubmed
STUDY DESIGN AND OBJECTIVES : This study by Srikandarajah et al is a retrospective cohort study of 200
CES patients . -
pubmed
Srikandarajah et al concluded that in CESI
patients , decompressive surgery within 24 hours of onset of autonomic symptoms reduces
bladder dysfunction at follow - up . -
pubmed
[ Preoperative , neuropathic component in
patients with
back pain ] . -
pubmed
OBJECTIVE : The goal of the study was the preoperative screening of a
neuropathic component in
patients with
vertebral compression fracture (
WKF ) ,
herniated disc (
NPP ) or
spinal cord compression (
SKS ) . -
pubmed
CONCLUSION : The painDETECT questionnaire was shown to be a very suitable instrument for evaluating the
neuropathic pain component in
patients with
dorsalgia . -
pubmed
Incidence of
post - anesthetic colic in non - fasted adult
equine patients . -
pubmed
The purpose of this study was to determine the incidence of
post - anesthetic colic in non - fasted adult
horses undergoing
isoflurane inhalant anesthesia for an elective , non - abdominal procedure at a single referral center . -
pubmed
INNOVATION Study ( Impact of Immediate Stent Implantation Versus Deferred Stent Implantation on Infarct Size and Microvascular Perfusion in
Patients With
ST - Segment - Elevation Myocardial Infarction ) . -
pubmed
A 65 - year - old
man presented with
diarrhea and
abdominal pain . -
pubmed
Changes in gastric smooth muscle cells of
diabetic rats with induced
gastroparesis were examined . -
pubmed
The
diabetic rat model was established by dividing
animals into a normal control group and
diabetic model groups examined at 2 , 4 and 6 weeks . -
pubmed
Contribution of Genetic Factors to Lower
DHEAS in
Patients with
Rheumatoid Arthritis . -
pubmed
METHODS : Surgical specimens from seven
hepatocellular carcinoma patients with
portal vein thrombosis and seven
patients without vascular invasion were utilized to analyze protein expression by proteomic technique . -
pubmed
The median survival time for the
patients with
portal vein thrombosis was much shorter [ 4 ( ranged 2.5 - 47 ) vs. 53 ( ranged 33 - 85 ) months , p = 0.002 ] . -
pubmed
Serum
urate levels are reported to be significantly lowered in
patients with
Parkinson ' s disease (
PD ) and inversely correlated to the risk and progression of
PD . -
pubmed
METHODS : In this randomised , double - blind , phase 3 trial , we recruited
patients aged 18 years and older with
glioblastoma from 165 hospitals in 22 countries . -
pubmed
FINDINGS : Between April 12 , 2012 , and Dec 15 , 2014 , 745
patients were enrolled ( 405 with MRD , 338 with significant residual disease [
SRD ] , and two unevaluable ) and randomly assigned to rindopepimut and
temozolomide ( n=371 ) or control and
temozolomide ( n=374 ) . -
pubmed
The most common grade 3 - 4 adverse events for all 369 treated
patients in the rindopepimut group versus 372 treated
patients in the control group were :
thrombocytopenia ( 32 [ 9 % ] vs 23 [ 6 % ] ) ,
fatigue ( six [ 2 % ] vs 19 [ 5 % ] ) ,
brain oedema ( eight [ 2 % ] vs 11 [ 3 % ] ) ,
seizure ( nine [ 2 % ] vs eight [ 2 % ] ) , and
headache ( six [ 2 % ] vs ten [ 3 % ] ) . -
pubmed
16
deaths in the study were caused by adverse events ( nine [ 4 % ] in the rindopepimut group and seven [ 3 % ] in the control group ) , of which one - a
pulmonary embolism in a 64 - year - old male
patient after 11 months of treatment - was assessed as potentially related to rindopepimut . -
pubmed
INTERPRETATION : Rindopepimut did not increase survival in
patients with newly diagnosed
glioblastoma . -
pubmed
We randomized 126
hypertensive patients on hemodialysis to a standardized predialysis
systolic BP of 110 - 140 mmHg ( intensive arm ) or 155 - 165 mmHg ( standard arm ) . -
pubmed
Most VNS research in the treatment of
inflammation have been acute studies on
rodent subjects . -
pubmed
SUMMARY : The
patient is a 56 - year - old
man who presented
dysphagia for solids and liquids ,
snoring ( score 10 ) and excessive
daytime sleepiness for 5 years . -
pubmed
DISCUSSIONS : This is the first reported case of
Forestier Syndrome (
FS ) associated with
Obstructive Sleep Apnea (
OSA ) that was proposed surgical treatment and the
patient evolved with complete symptom improvement . -
pubmed
Effectiveness of prowling with proprioceptive training on
knee hyperextension among
stroke subjects using videographic observation- a randomised controlled trial . -
pubmed
RESULTS : A total of 56
hypertensive events were evaluated in 30
patients . -
pubmed
Impairments of postural control , functional performance and strength in morbidly obese
patients awaiting bariatric surgery in comparison to healthy individuals . -
pubmed
Resistance to gastrointestinal nematodes in dairy
sheep : Genetic variability and relevance of artificial
infection of nucleus rams to select for resistant ewes on farms . -
pubmed
The alteration of microRNA ( miR)-130b expression has been associated with promoting or suppressing numerous types of
human cancer . -
pubmed
Tafenoquine receives regulatory approval in USA for prophylaxis of
malaria and radical cure of
Plasmodium vivax . -
pubmed
However , it has been reported to be associated with a lower risk of adverse events in
patients with
cancer or
acute coronary syndrome . -
pubmed
Results The unadjusted population included 1,536
HC patients and 330 non - HC
patients . -
pubmed
After baseline adjustment , the outcomes of
HC patients were significantly better than those of the non - HC
patients with respect to the primary endpoint , which was a combination of mortality from all causes , nonfatal
myocardial infarction (
MI ) , nonfatal neurological events , and major
bleeding [ hazard ratio ( HR ) 0.56 , 95 % confidence interval ( CI ) 0.39 - 0.81 ; p=0.002 ] , and the secondary endpoints , which included a combination of mortality from all causes , nonfatal
MI , and nonfatal neurological events ( HR 0.59 , 95 % CI 0.39 - 0.88 ; p=0.01 ) , and major
bleeding ( HR 0.42 , 95 % CI 0.20 - 0.88 ; p=0.02 ) . -
pubmed
Virtual touch IQ elastography in evaluation of Achilles tendon in
patients with
chronic renal failure . -
pubmed
PURPOSE : To evaluate the sonoelastographic changes in the Achilles tendon in
patients with
chronic renal failure (
CRF ) using virtual touch imaging quantification ( VTIQ ) elastography . -
pubmed
RESULTS : The median values of shear wave velocities of the Achilles tendon in
patients with
CRF were 7.19 m / s ( 4.23 - 9.77 m / s ) on the right and 6.98 m / s ( 4.00 - 9.82 m / s ) on the left , while they were 5.11 m / s ( 4.09 - 8.82 m / s ) on the right and 5.36 m / s ( 4.05 - 8.80 m / s ) on the left in controls . -
pubmed
The stiffness of the Achilles tendons in
patients with
CRF was found to be higher than that in controls ( right : P & lt ; 0.001 , left : P = 0.004 ) . -
pubmed
The thickness of the Achilles tendon did not significantly differ between the
patients with
CRF and healthy subjects . -
pubmed
However , the stiffness of the Achilles tendon measured with VTIQ elastography was demonstrated to be increased in the
patients with
CRF . -
pubmed
Upon irradiation with near - infrared light , they caused rapid
tumor shrinkage and significantly prolonged the survival of
tumor - bearing
mice . -
pubmed
Long - term functional outcomes and quality of life in
patients with
Hirschsprung ' s disease . -
pubmed
The aim of this cross - sectional study was to determine the long - term functional outcomes and quality of life ( QoL ) in
patients with
Hirschsprung ' s disease . -
pubmed
METHODS :
Patients with pathologically proven
Hirschsprung ' s disease older than 7 years were included . -
pubmed
METHODS : Tissue arrays were made from 135 paraffin - embedded
ESCC samples and examined for histone markers by immunohistochemistry , and 10 pairs of
cancer and
noncancerous mucosa tissues from
ESCC patients were investigated with Western blot . -
pubmed
Conclusions :
Copanlisib provides an alternative option for
patients with relapsed
FL . -
pubmed
Early surgical intervention for
patients with possible clinically silent somatotroph
adenoma : a case series . -
pubmed
CONCLUSION : Due to its potential for evolving to symptomatic disease , the risks of surgery and observation for
patients with somatotroph
adenoma should be carefully compared from the viewpoint of better health outcome . -
pubmed
METHODS : In a double - blind multicenter trial ,
patients with
Kawasaki disease received either
etanercept ( 0.8 mg / kg ; n = 100 ) or placebo ( n = 101 ) subcutaneously starting immediately after IVIg infusion . -
pubmed
RESULTS : Of 318 058
patients with
localized prostate cancer (
PCa ) , 55 566 ( 18.4 % ) underwent BT . -
pubmed
After propensity score - matching , 20 - year secondary
BCa incidence was 6.0 % in
patients who had undergone BT vs 2.4 % in those who had undergone
RP ( P & lt ; 0.001 ) and the respective 20 - year secondary RCa incidence was 1.1 % vs 0.5 % ( P & lt ; 0.001 ) . -
pubmed
Renal interstitial lymphangiogenesis is found in
patients with
chronic kidney disease (
CKD ) and a series of
animal models of
renal fibrosis . -
pubmed
A Retrospective Review of
Angiotensin II Use in Adult
Patients With Refractory Distributive
Shock . -
pubmed
RESULTS : A total of 16
patients received ATII for distributive
shock . -
pubmed
No
patients developed
thrombotic or infectious complications after receiving ATII . -
pubmed
A total of 223
adults with
class III obesity aged 41.20 + - 10.15 years were included . -
pubmed
Continued exposure of anti -
cancer drugs to
human iPS cell - derived cardiomyocytes can unmask their
cardiotoxic effects . -
pubmed
To develop a sensitive assay system for
cardiotoxicity , we examined effects of anti -
cancer drugs on contractile functions of
human iPS cell - derived cardiomyocytes by using non - invasive motion field imaging analysis with extended drug exposure time . -
pubmed
A novel mortality risk score predicting intensive care mortality in
cardiogenic shock patients treated with veno - arterial extracorporeal membrane oxygenation . -
pubmed
PURPOSE : Mortality after veno - arterial extracorporeal membrane oxygenation ( VA - ECMO ) implantation remains a major problem in
patients with
cardiogenic shock . -
pubmed
Materials and Methods : We examined if there existed
sensory - motor dysfunction in UB of aging
mice . -
pubmed
METHODS : A total of 15
patients with
periocular aging underwent monthly treatment sessions of 3DEEP and FSR for three months . -
pubmed
The primary aim of this study is to compare the effects of two , 6 - month physical activity programs on quality of life in
patients with
fibromyalgia . -
pubmed
CONCLUSION : The risk of underlying high - grade
cervical lesions in women with
ASC - US on cervical cytology was approximately 5 % , regardless of
HIV status . -
pubmed
Also , no increase was seen in the kidneys of non -
diabetic rats with
body weight similar to that of the
diabetics . -
pubmed
The content and composition of phospholipids were studied in the brain of
children who died from severe
malnutrition within the first 2 years of life , and compared with those obtained from well - nourished
children who died of accidents , or of illnesses not known to affect the central nervous system . -
pubmed
With the exception of a few
marasmic children under 1 year of age whose forebrain and cerebellum had higher
phospholipid concentration than normal , the concentration of the lipids on dry weight basis in all brain regions of the malnourished children was the same , regardless of age , as that in the children who were normal nutritionally . -
pubmed
Protein metabolism in
rats with
ventromedial hypothalamic lesions : dietary effects on
nitrogen retention . -
pubmed
Latency in vitro of
varicella - zoster virus in cells derived from
human fetal dorsal root ganglia . -
pubmed
A potential in vitro model of
varicella - zoster virus (
VZV ) latency was developed . -
pubmed
Dissociated
human dorsal root
ganglion cultures were infected with
VZV and maintained for 1 wk in the presence of
bromovinyl arabinosyl uracil , a potent inhibitor of
VZV . -
pubmed
VZV reactivated from 56 % of the cultures containing both neurons and satellite cells but not from cultures specifically enriched for either neurons , satellite cells , or
ganglion - derived fibroblasts . -
pubmed
These findings suggest that cultures containing both neurons and satellite cells provide a model system for
VZV persistence that possesses many properties of a
latent infection . -
pubmed
IgA B lymphocytes and subpopulations of T lymphocytes in the intestinal villi of
immunodeficient Wistar rats . -
pubmed
The clinical importance of these
arrhythmias in
humans is still a matter of debate . -
pubmed
This finding is consistent with the location of the
mouse twitcher mutation ( a model of
human GALC deficiency ) on chromosome 12 , which has substantial homology to
human chromosome 14 . -
pubmed
Twenty
patients underwent bilateral sagittal ramus osteotomy for the correction of
mandibular retrognathia . -
pubmed
Nuclear magnetic resonance studies of blood plasma and urine from
subjects with
chronic renal failure : identification of
trimethylamine - N - oxide . -
pubmed
We have used
1H- , 13C- and
14N - NMR spectroscopy to investigate the constituents of plasma and urine in 16
patients with
chronic renal failure (
CRF ) . -
pubmed
For the first time in the microcorrosion study of the nasal vascular network
human fetuses ( from the 12th to 24th week of intrauterine life ) obtained from
spontaneous abortions were used as well as
rats weighing from 250 to 300 gr . -
pubmed
Cells isolated from
patients were positive in expression except for cells from
acute myeloblastic leukemia with maturation (
AML M2 ) ,
acute hypergranular promyelocytic leukemia (
AML M3 ) and
erythroleukemia (
AML M6 ) developed from
myelodysplastic syndromes . -
pubmed
Gastric rupture in
horses : 50 cases ( 1979 - 1987 ) . -
pubmed
A computer - based search was conducted of medical and necropsy records of
horses admitted to the teaching hospital from Jan 1 , 1979 , to Dec 31 , 1987 , to obtain the records of all
horses admitted to the hospital for
colic and subsequently found to have
gastric rupture . -
pubmed
The results indicated that
horses on a diet of grass hay or grass /
alfalfa hay only or those that drank water from a bucket , stream , or pond were at increased risk for having
gastric rupture . -
pubmed
We present a rational approach to the workup and treatment of
patients with
head and neck cancer and a pulmonary nodule on chest radiography . -
pubmed
to renal
hypertensive mongrel dogs caused
decreases in systolic blood pressure which persisted for 3 h. Mild
salivation and
hyperventilation were observed with both doses . -
pubmed
34
patients with
myocardial hypertrophy , mean age 44 years , were examined by two - dimensional echocardiography and the degree of disproportion of the
hypertrophy of the different left ventricular segments was analyzed . -
pubmed
The three sequential inactivation treatments used in manufacture of the vaccine kill
hepatitis B virus and other infectious agents that may be present in
human plasma , including the
human T cell - lymphotropic virus that causes the
acquired immunodeficiency syndrome . -
pubmed
[ Calcified
thrombosis of the inferior vena cava in
children ] . -
pubmed
We reviewed the records of 2,400 consecutive
patients undergoing cardiac catheterization at USAF Medical Center Keesler between 1978 and 1984 and found 35
patients ( 1.5 percent of all cardiac catheterizations ) aged 35 years or less ( mean age , 32 years ) who underwent cardiac catheterization after
myocardial infarction . -
pubmed
These 35
patients ( group 1 ) were compared to a randomly selected group of 100
patients ( group 2 ) aged 55 years or greater who underwent cardiac catheterization for evaluation of
coronary artery disease during the same period . -
pubmed
Canine hemangiopericytoma : 23 cases ( 1967 - 1984 ) . -
pubmed
The medical records of 23 histopathologically confirmed cases of
canine hemangiopericytoma were reviewed . -
pubmed
[
Iatrogenic bronchial obstruction : study of 4 atopic
children with
bronchial obstruction induced by
acetyl salicylic acid ] . -
pubmed
The authors have studied the modification of the spirometric parameters in four
atopic children , during nonallergic diet , after administration of
ASA ( 400 mg ) . -
pubmed
When cells of each of these species are examined directly in infected tissue in the
rabbit tibia model
infection , their cell wall thickness is often much increased and very irregular around the circumference of the cell , their cell size is often increased , and their septation patterns are often severely deranged . -
pubmed
Apart from one exception , there has been no reference to the possible causation of large
liver abscesses by
M. - pubmed
Comparison of resuscitation of
sheep and
dogs after
bupivacaine - induced
cardiovascular collapse . -
pubmed
While the
bupivacaine was given , the
animals were made
apneic for 90 sec and then ventilated with 100 %
oxygen . -
pubmed
After the
bupivacaine administration ,
cardiovascular collapse occurred in the form of electromechanical dissociation progressing to
asystole in
dogs , whereas in
sheep the predominant rhythm was
ventricular fibrillation leading to
asystole . -
pubmed
The initial dose of
bupivacaine used to cause
cardiovascular collapse was 3.5 + /- 1.2 mg / kg in
sheep and 24.6 + /- 8.5 mg / kg in
dogs ( P less than 0.01 ) . -
pubmed
All
sheep and
dogs were resuscitated from the first
cardiovascular collapse . -
pubmed
All
dogs could be resuscitated after two additional
cardiovascular collapses induced by
bupivacaine , but no
sheep could be resuscitated after a second
cardiovascular collapse . -
pubmed
Three
patients were transplanted with the antibody - treated bone marrow cells during the first remission period after preconditioning with intensive chemotherapy and total body irradiation , while transplantations in two other
patients , who were in poor clinical condition , were done during the fourth remission period and the third
relapse , respectively . -
pubmed
these results suggested that autologous BMT with these three antibodies may be an effective mode of therapy for
Null - ALL patients . -
pubmed
An immunofluorescence study on the humoral immunity to adult
human oral mucosa in
recurrent aphthous stomatitis . -
pubmed
Lipoperoxidation after
carbon tetrachloride poisoning in
rats previously treated with antioxidants . -
pubmed
Aggressive behavior of
chimpanzees and
baboons in natural habitats . -
pubmed
[ Study of the cardiac output in 12
patients with
pheochromocytoma ] . -
pubmed
The biochemical characteristics of the
fracture hematoma in
man . -
pubmed
Equilibria for inversions induced by x - rays in isogenic
strains of
Drosophila pseudoobscura . -
pubmed
The method consists of applying
rhodamine - labeled whole bacteria to frozen sections of tissue in which
inflammation had been induced by injection of the same
bacterial strain . -
pubmed
, the same
bacteria used to induce the
tissue inflammation ) decreased binding of the labeled bacteria to a significant extent . -
pubmed
Primary cell cultures of normal
human epidermal keratinocytes and melanocytes and
human cell lines established from a primary
melanoma (
SK - PM-4 ) and metastatic melanomas (
HO # 1 ,
SK - MEL21 , and
SK - MEL37 ) contain specific and saturable receptors for the
tumor promoter
phorbol dibutyrate (
PDBu ) . -
pubmed
The binding of
[ 3H ] PDBu to
human keratinocytes was inhibited by the
tumor promoters
12 - O - tetradecanoylphorbol 13 - acetate and
teleocidin but not by
phorbol , which lacks
tumor - promoting activity . -
pubmed
The sensitivity of an enzyme - linked immunosorbent assay ( ELISA ) to detect pure native
Escherichia coli heat - stable toxin ( ST ) and to identify ST - producing
strains among clinical isolates was determined . -
pubmed
coli
strains tested of
human origin , which had been shown elsewhere by DNA hybridization probes to have ST - coding genes of either
human or
porcine origin , and in all of three ST - producing
E. - pubmed
coi
strains tested of
porcine origin . -
pubmed
The concomitant use of both ST and LT ELISAs provides a rapid , simple , and sensitive method for identifying among clinical isolates enterotoxigenic
strains of
E. - pubmed
Enzymatic changes in
dystrophic mice and their age dependency . -
pubmed
In most cases the activity of these enzymes was significantly elevated in the muscle of the
dystrophic mice . -
pubmed
The enzymatic changes in the bone of the
dystrophic mice were milder but more or less analogous to those in muscle . -
pubmed
As compared with cellular immunity tests , serological tests more frequently detect virus - specific immune response in
humans immunized with concentrated purified vaccine ( CV ) against tick - borne
encephalitis . -
pubmed
Serum
copper and
zinc levels in
melanoma patients . -
pubmed
However , not all
patients who died from
tumor metastases displayed persistent elevations of
SCL . -
pubmed
Computed tomography performed before and during treatment showed the occurrence of
tumor shrinkage in 18
patients ( 62 % ) , but in no case was a complete disappearance of the
tumor observed . -
pubmed
In 5 of these
patients , it was even possible to document
tumor shrinkage within the first month of treatment with low doses of the
dopamine agonists , whereas in other
patients ,
tumors shrank only after prolonged treatment with higher doses . -
pubmed
Visual field and acuity improved or normalized in 8 of the 13
patients with
visual defects ; in some cases , the improvement was reported as early as 2 days after the treatment was started . -
pubmed
In considering the high percentage of
patients showing
tumor shrinkage under medical treatment , we propose a course with
dopamine agonists as the first step in the management of
patients with
macroprolactinomas regardless of the presence of
visual impairments . -
pubmed
CONCLUSIONS : Use of antimicrobial agents for treating
vaginitis and
cervicitis do not cause a decrease in vaginal colonization by
Lactobacillus , which is detectable 1 week to 1 month after treatment . -
pubmed
The
genotoxic effects of low concentrations of
Se ( IV ) ,
Hg2 + , and
CH3HgCl added separately or together (
Se ( IV )/ CH3HgCI ) were studied by determining the induction of micronuclei in the binucleated erythrocytes of
Prussian carp . -
pubmed
In this article thyroid
metastasis in a
patient who was operated 11 years ago for
renal cell carcinoma is reported with the review of the literature . -
pubmed
The immunohistochemical analysis using the monoclonal antibodies to the blood group antigens was performed on the tissues of 387
colorectal cancers and 307
normal colonic tissues , and the relation between expression of these antigens and prognosis of the
patients with stage 2 was also investigated . -
pubmed
This
senile angiopathy is often , but inconstantly , associated with
Alzheimer ' s disease , and rarely causes
intracerebral hemorrhage , which is typically lobar and recurrent , occurring in elderly normotensive
patients with ou without
dementia . -
pubmed
Risk factors for development of
rhegmatogenous retinal detachment in
patients with
cytomegalovirus retinitis . -
pubmed
We studied 259
patients to determine the time - dependent risk and risk factors for the development of
retinal detachment in
patients with
cytomegalovirus retinitis . -
pubmed
A case of
multifocal reflex sympathetic dystrophy (
RSDS ) in a
patient with the tarda form of
osteogenesis imperfecta is described , followed by a review of the literature . -
pubmed
Microfractures of the trabecular bone in these
patients are proposed to be the initial stimulus in the pathogenesis of
RSDS by a mechanism similar to the one involved in the pathogenesis of
RSDS complicating other diseases associated with
bone fragility . -
pubmed
Between 65 % and 80 % of
patients have had significant improvement in terms of generalized
seizure control . -
pubmed
Although demonstrable in all
patients , these rarely have been problematic and in nearly all instances have been outweighed by the benefit in terms of
seizure control . -
pubmed
EEG with co - registered electrocardiography was recorded during at least two interictal epileptiform EEG discharges in each of 11
patients who later suffered from
sudden unexpected death in
epilepsy (
SUDEP ) , and from another 11 age and sex matched
patients , also with uncontrolled
tonic - clonic seizures , drawn from the same centre who were still alive at the time of investigation ( non - SUDEPs ) . -
pubmed
These agents have a useful role as selective pharmacologic research probes , and some of them can be used therapeutically as potent and selective anti -
nausea and antiemetic drugs , particularly in
patients undergoing
cancer chemotherapy treatment or general anesthesia procedures . -
pubmed
We report herein the case of a 54 - year - old
woman with a moderate
bleeding tendency , diagnosed as an
EDTA - dependent
pseudothrombocytopenia associated with a congenital
platelet release defect . -
pubmed
The recent correct diagnosis of a false
thrombocytopenia stimulated further laboratory investigation on the cause of the
patient 's
bleeding tendency with the consequent identification of a congenital
platelet deficiency of the
arachidonic acid pathway . -
pubmed
This finding is of relevant importance for the management of the
patient in case of elective surgery or
hemorrhagic emergency . -
pubmed
A meta - analysis of 12 selected randomized trials was performed to assess the efficacy of beta - blockers in the prevention of rebleeding and the effect on long - term survival in
patients with
cirrhosis . -
pubmed
Beta - blockers significantly increased the mean percentage of
patients free of rebleeding ( 21 % mean improvement rate , CI 95 % : 10%-32 % , P & lt ; .001 , relative risk 1.42 ) , the mean percentage of
patients free of
variceal rebleeding ( 20 % mean improvement rate , CI 95 % : 11%-28 % , P & lt ; .001 ) , the mean survival rate ( 5.4 % mean improvement rate , CI 95 % : 0%-11 % , P = .05 , relative risk 1.27 ) , the mean percentage of
patients free of
bleeding death ( 7.4 % , CI 95 % : 2%-13 % , P & lt ; .01 , relative risk 1.50 ) . -
pubmed
Five
patients would need to be treated with beta - blockers to prevent one rebleeding episode , 14 treated to prevent one
death , and 13 treated to prevent one
death from
bleeding . -
pubmed
In
patients with
esophageal varices , beta - blockers significantly increase the mean percentage of
patients free of rebleeding and the mean survival rate at 2 years . -
pubmed
Patients with uncomplicated
deep vein thrombosis and healthy controls were investigated as comparison groups . -
pubmed
Nitric oxide gas is a potent inhibitor of
platelet aggregation , with an IC50 of 3.6 microM for
rabbit platelets . -
pubmed
Mycoplasma penetrans was shown to be associated with
HIV infection and recent data have indicated the capacity of this mycoplasma to activate different functions of the immune system . -
pubmed
Normal tissue derived from
human brain and
tumor - cell lines derived from colon , ovary , and breast were not reactive . -
pubmed
Arterial vasodilation and vascular connective tissue changes in spontaneously
hypertensive rats . -
pubmed
We evaluated the arterial connective tissue response of 16 - week - old spontaneously
hypertensive rats ( SHRs ) to treatment with
minoxidil , 120 mg / L , drinking water for 10 weeks . -
pubmed
However , in addition to working as a cardioprotective agent ,
DEX has other potential applications that are outlined below and include ( 1 ) treatment of
patients with
acquired immunodeficiency syndrome - related
Kaposi ' s sarcoma , based on its activity as an angiogenesis inhibitor ; ( 2 ) enhancement of the effects of
cisplatin , based on its ability to increase the antiproliferative effects of
cisplatin on
human ovarian cancer cells ; ( 3 ) use for treatment of
iron overload states in
patients who are
allergic to
deferoxamine ; ( 4 ) treatment of
patients with
psoriasis ; ( 5 ) protection from hyperoxic effects on the lungs ; ( 6 ) protection from
bleomycin - induced
pulmonary fibrosis ; ( 7 ) attenuation of
acetaminophen - induced
hepatotoxicity ; ( 8) prevention of
mucositis ; and ( 9 ) other applications . -
pubmed
Adrenal - cortex autoantibodies and
steroid - producing cells autoantibodies in
patients with
Addison ' s disease : comparison of immunofluorescence and immunoprecipitation assays . -
pubmed
We studied 165
patients with
Addison ' s disease : 143
patients had different forms of autoimmune
Addison ' s disease ( 13 with
idiopathic premature ovarian failure ) and 22 had nonautoimmune
Addison ' s disease . -
pubmed
A high association between these two markers in
patients with different forms of autoimmune
Addison ' s disease and in those with short- or long - standing disease was found . -
pubmed
Determinants and predictors of the maximum walking speed during computer - assisted gait training in
hemiparetic stroke patients . -
pubmed
PARTICIPANTS : Thirty - four male
hemiparetic stroke patients received 8 weeks of computer - assisted gait training ( CAGT ) , which was initiated within approximately 3 months after
stroke onset . -
pubmed
Presarcomatous lesions of experimentally induced
sarcomas in
rats : morphologic , histochemical , and immunohistochemical features . -
pubmed
The present study , therefore , investigated the early phases of experimentally induced
rat sarcoma , which closely resembles
human malignant fibrous histiocytoma (
MFH ) . -
pubmed
Control
animals injected with
olive oil revealed acute inflammatory reactions after 30 days and no signs of chronic
inflammation or
malignancy after 60 and 120 days . -
pubmed
We concluded that these experimentally - induced
rat sarcomas develop in a triphasic pattern that resembles non - healing granulation tissue , with neovascularization preceding the occurrence of overt
MFH . -
pubmed
PATIENTS AND METHODS : Cytological samples were obtained by brushing biliary
strictures via a guide wire in 86
patients with
strictures of unknown status . -
pubmed
The overall specificity of less than 100 % resulted from
dysplasia in two
patients with
chronic pancreatitis and
inflammatory mass . -
pubmed
Selecting antihypertensive therapy in the pregnant
woman with
diabetes mellitus . -
pubmed
The choice of an antihypertensive agent for the pregnant
woman with
diabetes involves many factors . -
pubmed
In addition to playing key roles in the morphogenesis and sculpting of the organs to give rise to highly specialized forms and shapes , cell
death also participates in the programmed creation of specialized cell types for essential functions such as the selection of B cells in the immune system of
mammals and the formation of tracheids in the xylem of vascular plants . -
pubmed
Tobacco use prevalence and definitions and diagnoses of
nicotine addiction and dependence are described . -
pubmed
Effect of
ethanol on
polyunsaturated fatty acid biosynthesis in hepatocytes from spontaneously
hypertensive rats . -
pubmed
We investigated the effects of
ethanol on
PUFA biogenesis in hepatocytes of
Wistar Kyoto ( WKY ) rats and Spontaneously
Hypertensive Rats ( SHR ) . -
pubmed
Free
amino acid concentration in
hydatid cyst fluids from fertile and infertile
human and animal
Echinococcus granulosus . -
pubmed
11 free
amino acids from fertile (
sheep origin ) , nine from infertile (
cattle origin ) , 13 from infertile (
human origin )
hydatid cyst fluids and 19
amino acids from sera of patients with
hydatid infection were detected . -
pubmed
Glycine level in the fertile
hydatid cyst fluids (
sheep origin ) was significantly higher than those of infertile
cysts fluids (
cattle and
human origin ) and sera with hydatid patients . -
pubmed
Glycine level in fertile
hydatid cyst fluids was about two times more concentrated in infertile
cattle cyst fluids , 10 times more concentrated in infertile
human hydatid cyst fluids and 13 times more concentrated in sera with
hydatid patients . -
pubmed
On the other hand ,
alanine and
valine concentration in the fertile and infertile
cyst fluids were at similar level with the exception that
valine level in fertile
cyst fluids was 12 times more concentrated in infertile
human cyst fluids . -
pubmed
Our findings with respect to fertile and infertile
cysts fluids showed that free
amino acids concentrations in
cyst fluids were significantly , higher in sera from
patients with
hydatid cyst . -
pubmed
Total amount of free
amino acids content in fertile and infertile
cyst fluids was three to eight times higher from that of
human sera with hydatid patients . -
pubmed
[ Morphological picture of alimentary tract in the process of
food allergy in
children ] . -
pubmed
Morphological and histopathological changes in the mucosa of the stomach , duodenum and small and large intestine have been evaluated in 83
children aged between 12 months and 15 years with diagnosed
food allergy . -
pubmed
Among 23
children aged 7 - 15 years , in whose clinical picture abdomen
pains dominated , endoscopic examination of upper part of alimentary tract was performed . -
pubmed
In 43
children aged 12 months--8 years with dominating symptoms of protracted
diarrhoea and/or body mass deficiency , biopsy of small intestine mucosa was examined . -
pubmed
In 13
children ( 30.2 % ) subtotal villus
atrophy was observed , in 14
children ( 32.5%)--partial and in 16 children ( 37.3 % ) no small intestine mucosa
atrophy was noticed . -
pubmed
Large intestine
inflammation was observed in
food allergy process in 7
children . -
pubmed
Over 2/3 of examined
children with
food allergy showed
inflammation and
inflammation - atrophical changes in alimentary tract mucosa . -
pubmed
Arcanobacterium pyogenes , a common inhabitant of the mucosal surfaces of
cattle and
swine , is also a pathogen associated with a variety of
infections in these animals . -
pubmed
Ventricular coupling of electrical and mechanical dyssynchronization in
heart failure patients . -
pubmed
We studied the relationships of electrical and mechanical synchronization in
patients with
heart failure (
CHF ) and various degree of ventricular conduction delays . -
pubmed
In
CHF patients , electromechanical and contractile alterations are coupled ; regional activation may be an early parameter allowing the detection of
ventricular dyssynchronization . -
pubmed
For the in vivo studies , male
Sprague - Dawley rats underwent laparotomy , and small intestinal
ischemia was induced by clamping the superior mesenteric artery for 30 or 60 minutes , after which reperfusion was allowed for various time points up to 4 days . -
pubmed
METHODOLOGY : We studied 117
subjects with
chronic hepatitis C who failed treatment with
interferon - alpha , 87 of whom were " non - responders " and 30 " relapsers . " -
pubmed
METHOD : We performed a search of the published literature to identify all eligible articles pertaining to the surgical management of coexisting
cataract and
glaucoma in
adults . -
pubmed
The evidence was weak that extracapsular
cataract extraction ( ECCE ) alone results in short - term increase in IOP and was insufficient to determine the short - term impact of phacoemulsification
cataract extraction ( PECE ) on IOP in
glaucoma patients . -
pubmed
Long - term survival of
patients given hormonal therapy for metastatic
endometrial stromal sarcoma . -
pubmed
Endometrial stromal sarcoma (
ESS ) is a rare
neoplasm , mainly observed in premenopausal
women . -
pubmed
We describe two
women 44 and 34 years old at the time ESS diagnosis , who developed lung
metastases 3 and 6 years , respectively , after initial treatment : hysterectomy without ( case 1 ) or with oophorectomy ( case 2 ) , followed by hormone replacement therapy ( HRT ) for the latter . -
pubmed
The
aminotetraline derivative
( + /-)-( R , S )- 5,6 - dihydroxy-2 - methylamino-1,2,3,4 - tetrahydro - naphthalene hydrochloride (
CHF-1024 ) displays cardioprotection in postischemic
ventricular dysfunction of the
rat heart . -
pubmed
A model of isolated and perfused ( 15 ml / min ) electrically driven ( 300 beats / min )
rat heart subjected to global
ischemia ( 1 ml / min for 20 min ) and reperfusion ( 15 ml / min for 30 min ) was followed . -
pubmed
Stomatitis of
cattle and
horses due to
yellow bristle grass (
Setaria lutescens ) . -
pubmed
Ringworm epizootics in laboratory
mice and
rats : experimental and accidental transmission of
infection . -
pubmed
Treatment of experimental
tuberculosis of the
guinea pig with
dihydrostreptomicine and simultaneously with substances acting on the host . -
pubmed
Articular layer geometry , previously acquired from
human cadaver joints , was used in conjunction with computer - aided design and manufacturing technology to create these anatomically accurate molds . -
pubmed
Bladder augmentation ( 15 ) , bladder neck reconstruction ( 7 ) , fascial sling ( 3 ) , ureteral reimplants ( 1 ) , revision of
epispadias ( 2 ) and/or redo orchiopexy ( 1 ) were concurrently performed in 19
patients . -
pubmed
Subjects with a clinical history of
seasonal allergic conjunctivitis ( but no current symptoms or treatment at baseline ) were studied . -
pubmed
At visit 2 ( 2 weeks later ) ,
subjects were rechallenged to confirm the
allergic response . -
pubmed
The study comprised 48
patients ( 38
women and 10
men ) aged from 18 to 87 years , in whom thin needle aspiration biopsy revealed
cancer of the thyroid . -
pubmed
Postoperative histopathological examination showed
papillary cancer in 35
patients ,
oxyphilic cancer in 5
patients ,
anaplastic cancer in 4 and
medullary cancer in 4
patients . -
pubmed
A multicenter , placebo - controlled , double - blind study of efficacy of a new form of
carbamazepine (
Carbatrol ) in refractory
epileptic patients . -
pubmed
CBR was evaluated in 47
patients with uncontrolled partial onset
seizures . -
pubmed
During the 28 - day baseline period ,
patients were required to have at least two
seizures and to take
CBZ at a therapeutic level , a second antiepileptic drug was allowed but not
valproic acid (
VPA ) . -
pubmed
CASE REPORT : The
patient was a 10 year old
male with an acquired
esotropia of 20
PD at distance . -
pubmed
CONCLUSION : The slipped muscle may have been caused by insufficient suture and/or
excessive rubbing of the eye by the
patient . -
pubmed
Beneficial effects of
fluvastatin following percutaneous coronary intervention in
patients with unstable and
stable angina : results from the
Lescol intervention prevention study ( LIPS ) . -
pubmed
AIMS : To investigate the effect on risk of major adverse cardiac events ( MACE ) of lipid lowering treatment with
fluvastatin 80 mg / day after a first percutaneous coronary intervention in
patients with stable and
unstable angina . -
pubmed
METHOD AND RESULTS : This prespecified subgroup analysis of the LIPS ( Lescol intervention prevention study ) analysed 1658
patients with documented diagnosis ; 824 had
unstable angina ( 417 randomly assigned to
fluvastatin , 407 to placebo ) and 834 had stable
angina ( including silent
ischaemia ;
fluvastatin , 418 ; placebo , 416 ) . -
pubmed
Fluvastatin treatment reduced the risk of
MACE by 28 % compared with placebo ( p = 0.03 ) among
patients with
unstable angina , with no difference between
patients with stable and
patients with
unstable angina ( relative risk 1.07 , 95 % confidence interval 0.87 to 1.30 , p = 0.53 ) . -
pubmed
Fluvastatin reduced
coronary atherosclerotic events ( MACE excluding
restenosis ) by 36 % ( p = 0.006 ) among
patients with
unstable angina and 31 % ( p = 0.02 ) among
patients with
stable angina . -
pubmed
CONCLUSION : Treatment with
fluvastatin 80 mg / day produced significant reductions in
MACE and
coronary atherosclerotic events after percutaneous coronary intervention in
patients with average
cholesterol concentrations . -
pubmed
The beneficial effects of
fluvastatin are observed in
patients with unstable or
stable angina alike . -
pubmed
Simvastatin has the best evidence for its effectiveness in
patients without
CHD ; in contrast ,
atorvastatin has possibly more benefits for
patients with clinically evident
CHD . -
pubmed
The virulent , uncloned challenge stock ,
SIVsmE660 , represented a type of heterologous challenge and the intrarectal challenge modeled
infection across a mucosal surface . -
pubmed
Clostridium cadaveris bacteraemia : two cases and review . -
pubmed
We present 2 rare cases of
bacteraemia with
C. - pubmed
[ The influence of
hyperthyroidism and
glucocorticosteroid treatment on bone metabolism in
patients with
Graves ' disease and
ophthalmopathy ] . -
pubmed
UNLABELLED : The aim of the study was to assess influence of
hyperthyroidism and
glucocorticosteroid treatment on changes of bone turnover markers in
patients with
Graves ' disease and
thyroid ophthalmopathy (
TO ) . -
pubmed
Group I was composed of 26 euthyroid
Graves ' disease patients with
TO suitable for
steroid treatment . -
pubmed
Early identification and treatment of such individuals is essential to reduce transmission ; however , genetic and immunological correlates of
disease progression have not been well established in
man . -
pubmed
The
murine model has been a central tool for the elucidation of protective immune mechanisms that are essential for controlling
M. - pubmed
Additionally , the study of inbred
mice has revealed significant divergence in the susceptibility and
disease progression of individual
mouse strains to an
infection with M.tuberculosis . -
pubmed
The continued study of genetically disparate
mouse strains has the potential to identify immune mechanisms that correlate with increasing susceptibility to
tuberculosis . -
pubmed
These mechanisms will be highly applicable to studies in
man and assist in the early detection of individuals that are more vulnerable to the development of reactivation
tuberculosis . -
pubmed
In a double - blind comparison of the therapeutic effect of
amantadine in a natural outbreak of Hong Kong
influenza in January 1969 near Houston , Texas , the decrease in titers of virus in throat swabs from 12 treated
patients during the first 10 hr of treatment was appreciably greater than similar titers of virus from 16 untreated
patients ( P = 0.06 ) . -
pubmed
Cough ,
sore throat , and
nasal obstruction cleared more rapidly in treated
patients ( P & lt ; 0.05 ) , and decline of
fever in 6 treated
patients sick for less than 48 hr before treatment was more rapid than among 13 untreated
patients who had been ill for less than 48 hr . -
pubmed
To test this hypothesis , we assessed brain
acetate metabolism in five well - controlled
type 1 diabetic subjects and six nondiabetic control subjects using
13C magnetic resonance spectroscopy during infusions of
[ 2 -( 13 ) C ] acetate during
hypoglycemia ( approximately 55 mg / dl ) . -
pubmed
Brain
acetate concentrations were over twofold higher in the
subjects with
diabetes than the control subjects ( P = 0.01 ) . -
pubmed
The fraction of oxidative metabolism from
acetate ( P = 0.015 ) and the rate of
MCA transport ( P = 0.01 ) were also approximately twofold higher in the
diabetic subjects . -
pubmed
We conclude that during
hypoglycemia MCA transport in the brain was increased by approximately twofold in
patients with well - controlled
type 1 diabetes , as reflected by higher brain
acetate concentrations and rates of
acetate oxidation . -
pubmed
These data are consistent with the hypothesis that upregulation of
MCA transport may contribute to the maintenance of brain energetics during
hypoglycemia in
patients with
type 1 diabetes . -
pubmed
[ Study on pathogenic bacteria in
lung infection during mechanical ventilation for
patients with acute
organophosphorus pesticide
poisoning ] . -
pubmed
METHOD : In this article , we report some of the results from a study including 41
women , aged 37 - 69 years old , with nonmetastatic primary
breast cancer , referred to the Department of Oncology at Umea University Hospital in Sweden for postoperative radiotherapy . -
pubmed
RESULTS : No
anastomotic leaks or systemic complications were observed in the ECM - treated
animals . -
pubmed
METHODS : The records of 18
patients with proven histological diagnosis of
hepatobiliary and pancreatic tuberculosis were reviewed retrospectively . -
pubmed
RESULTS : Of 18
patients ( 11 men ) , 11 had
hepatobiliary TB while 7 had
pancreatic TB . -
pubmed
Five
patients ( 28 % ) had associated extra - abdominal
TB which helped in preoperative diagnosis in 3
patients . -
pubmed
Imaging demonstrated
extrahepatic bile duct obstruction in the
patients with
jaundice and in addition picked up liver , gallbladder and pancreatic masses with or without
lymphadenopathy ( peripancreatic / periportal ) . -
pubmed
Two
patients developed significant
postoperative complications ( pancreaticojejunostomy leak 1 intraabdominal
abscess 1 ) and 3 developed
ATT induced
hepatotoxicity . -
pubmed
CONCLUSION :
Tuberculosis should be considered as a differential diagnosis , particularly in young
patients , with atypical
signs and symptoms coming from areas where
tuberculosis is endemic and preoperative tissue and/or cytological diagnosis should be attempted before labeling them as
hepatobiliary and pancreatic malignancy . -
pubmed
Here , we demonstrate for the first time the antitumor effects of FK in
murine hepatocellular carcinoma (
HCC ) by constructing a FK eukaryotic expression vector ( pIRES - FK ) and transferring it into such
tumor cells . -
pubmed
Tumor rejection experiments were performed by injecting FK gene - modified
murine HCC cell line (
MM45T.Li ) into immunocompetent
mice , which significantly inhibited tumorigenicity or growth of
MM45T.Li - FK cells . -
pubmed
Splenic lymphocyte from
mice treated with MM45T.Li - FK were effective in the induction of
tumor - specific cytotoxic T cells . -
pubmed
Fischer-344 ( F344 ) rats exhibit
proteinuria and
insulin resistance in the absence of
hypertension as they age . -
pubmed
A recent case of
basilar artery occlusion (
BAO ) in a 62 - year - old
woman is presented , along with a review of the literature on the clinical aspects of the disorder and treatment options . -
pubmed
Ten
patients with
head and neck squamous cell cancer underwent resection of the
tumour followed by microvascular reconstruction with a free flap . -
pubmed
Segmental urethral dosimetry and
urinary toxicity in
patients with no urinary symptoms before permanent prostate brachytherapy . -
pubmed
Acinetobacter baumannii infections in a surgical intensive care unit : predictors of multi - drug resistance . -
pubmed
Patients with multi - resistant
infection , susceptible exclusively to
colistin , were compared with those sustaining
non - multi - drug resistant infection . -
pubmed
RESULTS : Among 411
patients , 52 ( 12.6 % ) developed
Acinetobacter infection . -
pubmed
CONCLUSION :
Acinetobacter baumannii infections are frequent and associated with high morbidity , mortality , and multi - resistance . -
pubmed
METHODS : 114
atherosclerotic patients ( 100
males , 61.7+/-6.7 years ) were included undergoing elective coronary revascularisation using the radial artery of the non - dominant forearm with non - pathological Allen 's Test . -
pubmed
Biomarkers of
inflammation in
patients with unclassified
polyarthritis and early
rheumatoid arthritis . -
pubmed
Irish wolfhounds ( IW ) and other large breed
dogs are most commonly disposed to
DCM . -
pubmed
In order to rule out a breed - specific haplotype that predisposes to
DCM , the polymorphisms were genotyped in 24 Elo
dogs , a breed mix established from nine different breeds . -
pubmed
Sixteen percent of all
head and neck cancer patients experienced a distant
metastasis of their primary
tumour . -
pubmed
Although short - term survival is high , nearly half of all
patients will develop
metastasis or die of complications of local
recurrences . -
pubmed
DESIGN : Two hundred fifty - five clinically stable
schizophrenia outpatients were randomly selected in Hong Kong and their counterparts matched according to sex , age , age at onset , and length of illness were recruited in Beijing , China . -
pubmed
PATIENTS OR PARTICIPANTS : Clinically stable
schizophrenia outpatients . -
pubmed
METHODS : We performed a case - control association study including 118 Hungarian
patients with
JIA and 118 sex - matched healthy controls . -
pubmed
Also revealed was the influence of viral replication of
hepatitis B virus in the development of complications , including
hepatocarcinoma . -
pubmed
The importance of
fatty acid liver disease was clearly shown in several studies confirming the influence of
diabetes in the presence of
inflammation and
fibrosis and the increase in the indication of liver transplantation for this disease , which may recur in the graft , especially in
patients with a high
body mass index . -
pubmed
METHODS :
Dysraphism was surgically created in 2 groups of 48
rat fetuses ; group 1 : control , and group 2 : treated with
corticosteroid . -
pubmed
Thirty - four
formalin - fixed and 19 fresh frozen
hepatitis B virus (
HBV)-related
cirrhosis samples were examined for the presence of
LLCC , small liver cell change (
SLCC ) , and
hepatocellular carcinoma (
HCC ) . -
pubmed
The characteristics of
HBV - related
LLCC are more consistent with dysplastic rather than merely reactive hepatocytes , whereas
cholestatic LLCC more likely represents reactive change with more stringent cell cycle checkpoint control . -
pubmed
Although product safety regarding
HIV ,
hepatitis , and other
blood - borne infections is currently excellent , potential new infectious agents require continued vigilant monitoring . -
pubmed
An examination of
chimpanzee use in
human cancer research . -
pubmed
Given that
cancer is a leading cause of
human death worldwide , one might expect that if chimpanzees were needed for , or were productive in ,
cancer research , then they would have been widely used . -
pubmed
This comprehensive literature analysis reveals that
chimpanzees have scarcely been used in any form of
cancer research , and that
chimpanzee tumours are extremely rare and biologically different from
human cancers . -
pubmed
Papers describing potential new
cancer therapies noted significant concerns regarding the
chimpanzee model . -
pubmed
It would therefore be unscientific to claim that
chimpanzees are vital to
cancer research . -
pubmed
On the contrary , it is reasonable to conclude that
cancer research would not suffer , if the use of
chimpanzees for this purpose were prohibited in the US . -
pubmed
Genetic differences between
humans and
chimpanzees , make them an unsuitable model for
cancer , as well as other
human diseases . -
pubmed
Verminous pneumonia in
dogs and
cats . -
pubmed
METHODS : 108
subjects presenting a first DSM - III - R
manic episode with
psychotic features were assessed at baseline and 12 months after stabilisation on symptoms and functional characteristics , and patients with
BD ( n=87 ) were compared with those with
SA bipolar subtype (
SAB ) ( n=21 ) . -
pubmed
RESULTS : SAB
patients had a higher prevalence of first degree relatives with
schizophrenia and a lower premorbid functional level . -
pubmed
At stabilisation and 12 months after stabilisation ,
SA patients had higher levels of negative symptoms , with poorer functional level at 12 months . -
pubmed
CONCLUSIONS : These data suggest
SA is a valid diagnosis in the early phase of
psychotic disorders considering it defines a subgroup of first episode
psychotic mania patients with distinct characteristics compared to
BD . -
pubmed
The cardiological evaluation of
patients with
cerebral ischaemia is of great clinical importance because diseases of the heart and aorta represent important sources of
embolism , because
ischaemic stroke is an index event that can lead to the diagnosis of
cardiovascular diseases and because the mortality and morbidity of
stroke patients are determined by concomitant
cardiac diseases . -
pubmed
Brachial - ankle
pulse wave velocity as a risk stratification index for the short - term prognosis of
type 2 diabetic patients with
coronary artery disease . -
pubmed
The incidence of
diabetes is increasing , and the disease has become an important predictor of prognosis in
patients with
coronary artery disease (
CAD ) , although adverse events often occur without warning . -
pubmed
This study tests the hypothesis that brachial - ankle
pulse wave velocity ( baPWV ) , a marker for arterial stiffness obtained by simple and noninvasive automated devices , can be a risk stratification index to predict prognosis in diabetic
patients with
CAD . -
pubmed
Data were available on 564
CAD patients , with a median follow - up of 25.4 months . -
pubmed
The higher baPWV among
diabetic patients was defined as a median baPWV of 1730 cm s(-1 ) or more . -
pubmed
The 3 - year Kaplan - Meier estimates of event - free survival were 72.8 % in
diabetic patients with lower baPWV and 51.3 % in those with higher baPWV , respectively ( P=0.031 ) . -
pubmed
Recent studies have shown that whole - body vibration improves posture and gait control in
stroke patients . -
pubmed
Patients with
degenerative cerebellar disease suffer from
ataxic gait also which is characterised by the variation of gait pattern . -
pubmed
In this retrospective data analysis , we report on the use of
adrenaline in 20
neonates with
birth asphyxia and
shock that was refractory to
dopamine and
dobutamine . -
pubmed
Selective
serotonin ( 5 - HT ) re - uptake inhibitors ( SSRIs ) are commonly used in the treatment of generalized
anxiety disorder in
Humans . -
pubmed
However , because only few
animal models display overt
anxious - like behavior , detailed preclinical studies of the anxiolytic properties of antidepressants are still lacking . -
pubmed
Deletion of both receptors resulted in ( i ) higher emotionality of
animals , as observed in three unconditioned paradigms of
anxiety ( open field , elevated plus maze and novelty suppressed feeding tests ) ; ( ii ) a 200 % increase in the mean spontaneous firing rate of 5 - HT neurons in the dorsal raphe nucleus ( DRN ) compared to 5 - HT(1A/1B)+/+
mice ; ( iii ) elevated basal dialysate levels of
5 - HT in the DRN and frontal cortex ; ( iv ) an exaggerated response to acute
paroxetine administration in microdialysis experiments , and ( v ) increased basal core body temperature . -
pubmed
METHODS : Twenty - four
patients with
coronary disease and
left ventricular systolic dysfunction ( ejection fraction & lt;45 % ) underwent RTMCE before and 3 months after CABG . -
pubmed
In order to study the effect of aging on T - H - induced
mitochondrial dysfunction , we recently developed a
rodent mitochondrial genechip with probesets representing mitochondrial and nuclear genes contributing to mitochondrial structure and function . -
pubmed
CONTEXT : This article reviews diverse aspects of the prevention of
urinary tract infections , including confirmation of the diagnosis , application of hygiene and dietary measures , antibacterial prophylaxis ( preferably consisting of a single nocturnal oral dose per day of an antibiotic or drug with high urinary excretion and good tolerance ) , and administration of vaccines made with
Escherichia coli and other Gram - negative bacilli , consisting of immunostimulating fractions of
E. - pubmed
Propagation of
herpes simplex virus via pontine fiber in a case of
brainstem encephalitis . -
pubmed
OBJECTIVE : To explore the mechanism of protective effect of
Sphingosine-1 - phosphate(
S1P ) in cultured neonatal
rat cardiomyocytes dining simulated
hypoxia / reoxygenation . -
pubmed
CONCLUSION :
SiP can obviously restrain apoptosis in curtured
rat neonatal cardiomyocytes during simulated
hypoxia / reoxygenation . -
pubmed
PARTICIPANTS : 10 840
patients newly prescribed
tiotropium ( n=4767 ) or LABA ( n=6073 ) , at least 40 years old , and not having
asthma as their only
respiratory illness . -
pubmed
Adding
HPV testing to cytology screening reduced & gt;= grade 3
cervical intraepithelial neoplasia at 5 years . -
pubmed
Intravenous drug use ( adjusted odds ratio [ ( adj ) OR ] , 30.5 ; 95 % confidence interval [ CI ] , 18.9 - 49.1 ) , cohabitation or sexual partnership with an
hepatitis C virus (
HCV ) carrier ( ( adj ) OR , 11.2 ; 95 % CI , 6.6 - 19.2 ) , nosocomial exposure ( ( adj ) OR , 6.6 ; 95 % CI , 4.6 - 9.4 ) ; unsafe sexual practices ( ( adj ) OR , 3.1 ; 95 % CI , 1.9 - 5.2 ) , and cosmetic treatments with percutaneous exposure ( ( adj ) OR , 1.7 ; 95 % CI , 1.2 - 2.4 ) were independently associated with
acute hepatitis C. -
pubmed
LCH most commonly occurs as a
localised solitary bone lesion and appears predominantly in paediatric
patients . -
pubmed
The presenting features of the
patient included
fever ,
bleeding gums and
seborrheic dermatitis - like
rash . -
pubmed
The
patient had poor LV function along with moderate
pulmonary hypertension . -
pubmed
Extending helminth control beyond
STH and
schistosomiasis : the case of
human hymenolepiasis . -
pubmed
The mean age of the
patients at the time of
trauma was 9.83 + - 2.8 years . -
pubmed
Safety and immunogenicity of booster immunization with 7 - valent
pneumococcal conjugate vaccine in
children with
idiopathic nephrotic syndrome . -
pubmed
Safety and immunogenicity of a booster dose of 7 - valent
pneumococcal conjugate vaccine ( PCV7 ) were evaluated in 29
patients with
idiopathic nephrotic syndrome (
INS ) , who had been primed 12 months earlier with one dose of PCV7 . -
pubmed
PCV7 was not associated with increased risk of
INS relapse ( RR=0.77 , p=0.8 ) and serotype - specific antibodies increased in all subjects at 1 month ( p<0.01 ) . -
pubmed
Additional PCV7 doses could be safely given in
children with
INS to increase circulating antibodies above the protective threshold . -
pubmed
However , its expression pattern and biological roles in
human ovarian cancers are not clear . -
pubmed
Together , these findings implicate GEMMs as powerful preclinical tools with the capacity to recapitulate relevant
human disease biology , and support the use of genetic signatures generated in these models to facilitate future drug discovery and validation efforts . -
pubmed
We studied the longitudinal growth of the short bones in the hand of a 15 - yr - old
girl with
PHP type Ia who had been followed for
congenital hypothyroidism . -
pubmed
Plasmodium vivax , the pathogen causing endemic
malaria in
humans worldwide , is responsible for extensive disease morbidity . -
pubmed
These drugs with novel scaffolds may act as potent drugs for treating
malaria caused by
P. - pubmed
Reversion by
vitamin E treatment of the oxidative damage but not of the advancement in reproductive senescence produced by neonatal
hypoxia or
hypoxia -
ischemia in female
rats . -
pubmed
Previously we described advanced reproductive senescence (
premature loss of regular cyclicity ) in female
rats subjected to perinatal
H or H plus unilateral ischemia ( HI ) associated with changes in the hypothalamic expression of estrogen and opioid receptors . -
pubmed
Effect of the aqueous extract of
Foeniculum vulgare ( fennel ) on the kidney in experimental
PCOS female
rats . -
pubmed
In this research , renoprotective effect of the aqueous extract of
Foeniculum vulgare ( AEF ) in experimental
PCOS female
rats is studied . -
pubmed
Animals in the second group were non
poly cystic ovary syndrome (
PCOS )
rats which were treated with intragastric administration of aqueous extract of
F. - pubmed
RESULTS : The mean values of blood
urea nitrogen in
PCOS rats treated with low dose of AEF and EV and non - treated , was significantly ( p<0.05 ) increased compared with non - PCOS and
PCOS rats treated with high dose of AEF . -
pubmed
Moreover , histopathological changes of kidney samples were comparable in
PCOS rats with respect to treated groups with AEF . -
pubmed
on renal function in
PCOS rats . -
pubmed
[ Essential
thrombocythemia : baseline characteristics and risk factors for survival and
thrombosis in a series of 214
patients ] . -
pubmed
Benzbromarone consistently attenuates BK- ,
formalin- , or
monosodium urate - induced inflammatory
pain in
rat and
mouse models . -
pubmed
This study looked at antibiotic dosing and treatment failure in the
obese population from the primary care perspective and accounts for
BMI range , weight , comorbid
diabetes , and
tobacco use . -
pubmed
METHODS : This study was a retrospective chart review of 637 adult primary care
patients designed to evaluate rates of treatment failure of outpatient
cellulitis among
patients of varying
BMI . -
pubmed
While controlling for age , gender , race , diagnosis of
diabetes mellitus , and
tobacco use , a
BMI of & gt;=50 kg / m(2 ) and a weight & gt;=120 kg was associated with adverse outcomes with an odds ratio of 2.440 ( 95 % CI , 1.260 - 4.724 ; P = .008 ) and 2.246 ( 95 % CI , 1.154 - 4.369 ; P = .017 ) , respectively . -
pubmed
CONCLUSIONS :
Patients with
cellulitis weighing & gt;120 kg or with a
BMI & gt;=50 kg / m(2 ) were at greatest risk for treatment failure in the outpatient setting , even when controlling for comorbid
diabetes and
tobacco use . -
pubmed
METHODS : Ninety
women between 22 and 36 weeks ' gestation were included and divided into two groups : group A comprised 41
women at 22 to 36 weeks ' gestation who were suffering from threatened
premature labor ; and group B comprised 49
women at 22 to 36 weeks ' gestation with
preterm premature rupture of the membranes . -
pubmed
Gluteal fasciocutaneous ( FC ) rotation flaps can still be used to close sacral pressure
ulcers but tend to develop a large
dog - ear on the buttock . -
pubmed
OBJECTIVE :
Epilepsy is a serious , potentially life - shortening
brain disorder that occurs in
patients of all ages and races . -
pubmed
A total of 2 - 4 % of
people have experienced
seizures at least once in their lifetime . -
pubmed
In this manner , we compare the
recurrence rates of
epilepsy in first
seizure patients treated with
sodium valproic acid as an antiepileptic drug versus a placebo . -
pubmed
MATERIAL & amp ; METHODS : In a randomized clinical trial study , 101 first
seizure patients were randomly divided into two groups : one group was treated with antiepileptic drugs (
sodium valproate 200 mg , three times a day ) and the other group was given a placebo . -
pubmed
All recurrence cases came from the placebo group , with four
patients suffering an additional
seizure after four months and between 4 - 6 month follow up . -
pubmed
Our results suggest that drug therapy for
people after their first
seizure attack might reduce the probability of
seizure recurrence . -
pubmed
BACKGROUND AND OBJECTIVES : Reliability is an essential condition for using quantitative sensory tests ( QSTs ) in research and clinical practice , but information on reliability in
patients with
chronic pain is sparse . -
pubmed
The aim of this study was to evaluate the reliability of different QST in
patients with
chronic low back pain . -
pubmed
METHODS : Eighty - nine
patients with
chronic low back pain participated in 2 identical experimental sessions , separated by at least 7 days . -
pubmed
CONCLUSIONS : Most QST measurements have acceptable reliability in
patients with
chronic low back pain . -
pubmed
Multisite Study of an Implanted Continuous
Glucose Sensor Over 90 Days in
Patients With
Diabetes Mellitus . -
pubmed
BACKGROUND : Continuous
glucose monitoring ( CGM ) , which enables real - time
glucose display and trend information as well as real - time alarms , can improve glycemic control and quality of life in
patients with
diabetes mellitus . -
pubmed
The procedure could be completed in all of the
patients but was interrupted in 6
patients in group PF because of
desaturation ( 5 ) or sudden patient movement ( 1 ) . -
pubmed
This study was aimed at comparing the prevalence and severity of
chronic periodontitis of
HIV - seropositive patients with that of
HIV - seronegative persons using the community periodontal index ( CPI ) . -
pubmed
CONCLUSION :
HIV - seropositive patients had more severe chronic
periodontitis than the
HIV - seronegative controls , which was independent of lower education . -
pubmed
Grapefruit Derived
Flavonoid Naringin Improves
Ketoacidosis and Lipid Peroxidation in
Type 1 Diabetes Rat Model . -
pubmed
BACKGROUND : Hypoglycemic effects of
grapefruit juice are well known but the effects of
naringin , its main
flavonoid on
glucose intolerance and metabolic complications in
type 1 diabetes are not known . -
pubmed
OBJECTIVES : To investigate the effects of
naringin on
glucose intolerance , oxidative stress and
ketonemia in
type 1 diabetic rats . -
pubmed
METHODS :
Sprague - Dawley rats divided into 5 groups ( n = 7 ) were orally treated daily with 3.0 ml / kg
body weight ( BW)/day of distilled water ( group 1 ) or 50 mg / kg BW of
naringin ( groups 2 and 4 , respectively ) . -
pubmed
Letter by Madias Regarding Article , " Three Recurrent Episodes of Apical - Ballooning
Takotsubo Cardiomyopathy in a
Man " . -
pubmed
After uterine and muscle closure but before skin closure , Group A was administered local subcutaneous
wound infiltration of Injection ( Inj )
ropivacaine 0.75 % 150 milligram ( mg ) or 20 millilitres(ml ) whereas , group B
patients were given a local subcutaneous
wound infiltration of Inj
magnesium sulphate 750 mg ( 1.5 ml of Inj 50 %
Magnesium sulphate ) added to Inj
ropivacaine 0.75 % ( 18.5 ml ) making a total volume of 20 ml . -
pubmed
RESULTS : Of 510 specimens cultured , the total culture positivity obtained was 11.8 % ( 60 ) encompassing 54 ( 10.6 % )
Mycobacterium tuberculosis and 6 ( 1.2 % ) non - tubercular mycobacteria (
NTM ) . -
pubmed
In summary , we found that inter -
individual variability in non - coding regions affect the response to
hypoxia and could potentially impact on the progression of
pulmonary diseases . -
pubmed
Antimicrobial properties on tester
strains (
Bacillus cereus ,
Escherichia coli ,
Staphylococcus aureus and
Pseudomonas aeruginosa ) and in vitro anti - proliferative activity were evaluated . -
pubmed
The
cabbage extracts exhibited antimicrobial activity mainly on the ninth day after the expiry date and retained significant inhibitory effects against
colon carcinoma (
CaCo-2 ) cells . -
pubmed
Results confirmed that JsAE delayed the onset of
seizures and reduced frequency of tonic
convulsion and mortality in
mice . -
pubmed
Fifteen
patients , 10
males and 5 females , between 10 - 27 years age with different benign
vascular skin lesions i.e.haemangioma ( 3 ) and
lymphangioma circumscriptum ( 2 ) were taken up for this study . -
pubmed
The
patients with
granuloma pyogenicum showed excellent response with complete disappearance of the lesions while the
patients with
haemangiomas ,
lymphangio - haemangiomas and
lymphangioma circumscriptum improved by 70 - 90 % . -
pubmed
Transient
hypopigmentation and mild
scarring were seen in all the
patients except in
patienls with
granuloma pyogenieum . -
pubmed
A total of 126
CM patients and 126 healthy
individuals were recruited for the study . -
pubmed
The
CM patients were treated with
amphotericin B (
AmB ) . -
pubmed
OBJECTIVE : The goal of this study was to investigate the utility of the INECO Frontal Screening ( IFS ) for differentiating
bv - FTD patients from
patients with
Major Depression . -
pubmed
RESULTS :
Patient groups differed significantly on the motor inhibitory control ( U=437.0 , p<0.01 ) , verbal working memory ( U=298.0 , p<0.001 ) , spatial working memory ( U=300.5 , p<0.001 ) , proverbs ( U=341.5 , p<0.001 ) and verbal inhibitory control ( U=316.0 , p<0.001 ) subtests , with bv -
FTD patients scoring significantly lower than patients with
depression . -
pubmed
CONCLUSION : Our results suggest the IFS can be considered a useful tool for detecting
executive dysfunction in both
depression and
bv - FTD patients and , perhaps more importantly , that it has the potential to help differentiate these two conditions . -
pubmed
Children with
Wiskott - Aldrich syndrome are often initially diagnosed with
immune thrombocytopenic purpura , which can lead to inappropriate treatment and delays to life - saving definitive therapy . -
pubmed
We unravel several taxonomic
confusions and uncertainties in the earlier literature that had their origins in the classification of
Boroecia maxima and Boroecia antipoda ( Muller , 1906 ) as subspecies of
Boroecia borealis . -
pubmed
Surgical procedures such as
tumor resection and biopsy are still the gold standard for diagnosis and ( determination of ) treatment of solid
tumors , and are prognostically beneficial for
patients . -
pubmed
This would allow precise stratification of high - risk
patients requiring more aggressive treatment from low - risk
ESCC patients who can forego radical surgery . -
pubmed
INTRODUCTION : There is a major epidemic of
obesity , and many
obese patients suffer with respiratory symptoms and disease . -
pubmed
After its introduction in clinical practice , the use of postsurgical
radioiodine treatment was generalized to almost every
patient with
differentiated thyroid cancer , with the exception of unifocal
microcarcinomas . -
pubmed
Expert commentary : Although there is general consensus about the recommendation for very low - risk (
microcarcinomas ) and high - risk
patients - no indication for routine postoperative
radioiodine and clear indication for
radioiodine treatment , respectively , the recommendation for low- and intermediate - risk
patients is still under debate . -
pubmed
We consider that these recommendations are in accordance with the best evidence available
today , and we would like to emphasize that
radioiodine is generally favored for most intermediate - risk
patients , especially in the presence of extensive
lymph node disease or older age . -
pubmed
Diagnosis and Clinical Course of Three
Adolescents with
Amiodarone - Induced
Hyperthyroidism . -
pubmed
In the
pediatric population , long - term
amiodarone treatment is rarely indicated because of its severe side effects including
thyroid function impairment . -
pubmed
We present three adolescent
patients developing
amiodarone - induced
thyrotoxicosis in the months after
amiodarone therapy . -
pubmed
A latency period for
thyroid dysfunction has been described in adulthood but was not previously reported in pediatric
patients . -
pubmed
In two
patients ,
hyperthyroidism was transient and resolved without treatment . -
pubmed
In contrast , in one male
patient overt and severe
hyperthyroidism developed . -
pubmed
Clinical evaluation proved an
amiodarone - induced destructive
thyroiditis in this
patient . -
pubmed
Amiodarone - induced
thyroid dysfunction is frequent also in pediatric
patients with long - term
amiodarone treatment . -
pubmed
Careful follow - up is needed , as symptoms might be associated with the underlying
cardiac disease in these
patients . -
pubmed
In this study , we suggest that the creation of
human -
primate chimeras - specifically , the transfer of
human stem cells into ( non - ape )
primate hosts - could not only surpass the limitations of current
monkey models of neurological and
psychiatric disease but would also raise important ethical considerations concerning the use of
monkeys in invasive research . -
pubmed
METHODS : Twenty - seven
patients with
aortic stenosis were included , 15 of whom underwent repeated imaging 4 weeks apart . -
pubmed
Infection with
Candida albicans can prove lethal in immuno - compromised patients . -
pubmed
CRYPTOCOCCAL meningitis in a
HIV negative newly diagnosed
diabetic patient : a CASE report . -
pubmed
BACKGROUND : This case report emphasizes the need to recognize
cryptococcus as a possible cause of
meningitis in non -
HIV patients in Sub - Saharan Africa and to highlight the possibility of grave outcomes due to the paradoxical immune response in
diabetic patients with
cryptococcus meningitis . -
pubmed
CONCLUSIONS : With the rising prevalence of
diabetes in Sub - Saharan Africa , coupled with the low levels of adequate
glucose control ,
cryptococcal meningitis should be considered in the differential diagnosis for
diabetic patients presenting with chronic
headache ,
fever and
neurologic deficits . -
pubmed
Cytoprotective agent for
peptic ulcer prevention in
patients taking dual antiplatelet agents : A randomized , double - blind placebo - controlled trial . -
pubmed
BACKGROUND AND AIM : Long - term use of dual antiplatelets is increasing , and most
patients need primary
peptic ulcer prophylaxis . -
pubmed
Patients receiving dual antiplatelets for & gt;= 1 year with no history of
peptic ulcer bleeding or
perforation were recruited and randomly assigned to the
rebamipide ( 300 mg / day ) group or the placebo group . -
pubmed
During the 12 months of follow up , 13
patients ( 43.3 % ) taking
rebamipide and 19 ( 65.5 % ) taking the placebo experienced
mucosal injury ( P = 0.07 ) . -
pubmed
Two
patients ( 6.7 % ) taking
rebamipide and eight ( 27.6 % ) taking the placebo had
peptic ulcers & gt;= 5 mm or & lt ; 5 mm with
pigmented spots ( P = 0.03 ) . -
pubmed
CONCLUSION :
Rebamipide is safe and may prevent
peptic ulcers & gt;= 5 mm in diameter or those with pigmented
spots in
patients receiving dual antiplatelets for 1 year ( NCT02166008 ) . -
pubmed
OBJECTIVES : This study aimed to provide real - world data on the characteristics and treatment of
patients with
multiple myeloma (
MM ) at the time of death . -
pubmed
CONCLUSIONS : These real - world data could be used to help develop strategies for improving survival in
patients with
MM and to support management tailored to the stage of disease . -
pubmed
METHODS : Twenty - nine
girls with adolescent
idiopathic scoliosis formed the
scoliotic group and 22 able - bodied girls formed the non - scoliotic group . -
pubmed
PURPOSE : In
patients with
ICA stenosis , increased peak systolic velocity is a marker of
stenosis at risk of
ischemic stroke . -
pubmed
METHODS : After review board approval , 15 healthy controls and 12
patients presenting ICA
stenosis were explored with Doppler ultrasonography and 4DFlow MRI . -
pubmed
This review aims to catch readers ' attention to the clinical diversity of phenotypes , differential diagnosis , and management of
patients with
FMF . -
pubmed
Differential expression of miRNAs and their targets in
wax - deficient rapeseed . -
pubmed
Metabolic impact of
pheochromocytoma /
paraganglioma : Targeted metabolomics in
patients before and after
tumor removal . -
pubmed
Patients with a
noradrenergic tumor phenotype had more pronounced alterations compared to those with an adrenergic
tumor phenotype . -
pubmed
CONCLUSIONS : This first large prospective metabolomics analysis of
PPGL patients demonstrates broad metabolic consequences of
catecholamine excess . -
pubmed
Robust impact on lipid and
amino acid metabolism may contribute to increased morbidity of
PPGL patients . -
pubmed
METHODS : Sixteen
patients presenting with symptomatic
SICAD from September 2006 to October 2018 were reviewed retrospectively . -
pubmed
Four
patients received early intervention because of
aneurysmal dilatation or distal
hypoperfusion . -
pubmed
Although collaterals prevented further
hepatic ischaemia , one of these four
patients failed in delayed intervention because of extensive
thrombi completely occluding the hepatic artery . -
pubmed
In the remaining eight
patients who were managed conservatively , three ( 37.5 % ) showed regression of disease , one ( 12.5 % ) showed partial regression , and five ( 62.5 % ) showed no change in intimal flap or
thrombosis , but all had symptomatic improvement . -
pubmed
CONCLUSIONS : Early intervention in symptomatic
SICAD patients may be necessary in over 50 % of
patients , and endovascular stenting has durable long term outcomes . -
pubmed
Burn wound infections and
Pseudomonas aeruginosa . -
pubmed
The treatment for the
patients with
Bankart lesion is the arthroscopic repair . -
pubmed
a standard two anterior portals technique and a single anterior portal technique in
patients with
RDS . -
pubmed
METHODS :
Patients with traumatic
RDS met the inclusion criteria were managed with Bankart repair using either two anterior portals ( Group A ) or a single anterior portal ( Group B ) technique . -
pubmed
Serum
vitamin K1 associated to
microangiopathy and/or
macroangiopathy in
individuals with and without
diabetes . -
pubmed
However , difficult - to - cure /
cirrhotic patients typically require a longer treatment duration and less is known regarding the long - term durability of SVR or effect on
liver disease progression ; to assess this , the IMPACT study followed
patients for a 3 - year period after end of treatment . -
pubmed
A metabonomics and lipidomics based network pharmacology study of qi - tonifying effects of honey - processed
Astragalus on
spleen qi deficiency rats . -
pubmed
Our previous study has demonstrated that honey - processed
Astragalus exhibited a better effect on reinforcing qi ( vital energy ) and immune improvement toward
spleen qi deficiency compared with radix
Astragali . -
pubmed
In this study , we evaluated the qi - tonifying effects of honey - processed
Astragalus on
spleen qi deficiency rats and predicted the mechanisms by aggregating metabonomics , lipidomics and network pharmacology . -
pubmed
Therefore , to determine the role of MicroRNA-146a and MicroRNA-155 in
MS patients , their expression levels in serum of
MS patients were compared with healthy controls . -
pubmed
In this study , the expression levels of MicroRNA-146a and MicroRNA-155 in 30 serum samples of
MS and healthy
patients as a control group . -
pubmed
MicroRNA-146a and MicroRNA-155 levels were increased in
patients with
MS compared to controls . -
pubmed
The initial survey determined the number of
children with
pBE . -
pubmed
ABR abnormalities were present in 88 of 117
patients . -
pubmed
A phase 2B randomised trial of
hyperbaric oxygen therapy for
ulcerative colitis patients hospitalised for moderate to severe flares . -
pubmed
BACKGROUND : Hyperbaric
oxygen has been reported to improve disease activity in hospitalised
ulcerative colitis (
UC )
patients . -
pubmed
METHODS : We enrolled
UC patients hospitalised for acute flares ( Mayo score 6 - 12 ) . -
pubmed
CONCLUSION : Hyperbaric
oxygen appears to be effective for optimising response to intravenous
steroids in
UC patients hospitalised for acute flares , with low rates of re - hospitalisation or colectomy at 3 months . -
pubmed
Association of
Triglyceride Deposit
Cardiomyovasculopathy With Drug - Eluting Stent
Restenosis Among
Patients With
Diabetes . -
pubmed
METHODS : This study included 162
HCM patients ( 61 %
men ) who underwent septal myectomy . -
pubmed
This study aims to introduce near - infrared spectroscopy analysis technology into the production process of fermented
Cordyceps powder , including
strain culture ,
strain passage , strain fermentation , strain filtration , strain drying , strain pulverizing , and strain mixing . -
pubmed
A multi - omic study for uncovering molecular mechanisms associated with
hyperammonemia - induced
cerebellar function impairment in
rats . -
pubmed
Patients with
liver cirrhosis may develop covert or minimal
hepatic encephalopathy (
MHE ) . -
pubmed
Rats with chronic
HA show some motor and cognitive alterations reproducing
neurological impairment in cirrhotic
patients with
MHE . -
pubmed
Neuroinflammation and altered neurotransmission and signal transduction in the cerebellum from
hyperammonemic (
HA )
rats are associated with motor and
cognitive dysfunction , but underlying mechanisms are not completely known . -
pubmed
The aim of this work was to use a multi - omic approach to study molecular alterations in the cerebellum from
hyperammonemic rats to uncover new molecular mechanisms associated with
hyperammonemia - induced
cerebellar function impairment . -
pubmed
In summary , this is a good approach to find altered pathways , which helps to describe the molecular mechanisms involved in the alteration of brain function in
rats with chronic
HA and to propose possible therapeutic targets to improve
MHE symptoms . -
pubmed
Inferring high - resolution
human mixing patterns for
disease modeling . -
pubmed
The growing need for realism in addressing complex public health questions is , however , calling for accurate models of the
human contact patterns that govern the
disease transmission processes . -
pubmed
Owners of 6/76 PER / EXO show
cats stated that their cat had increased
respiratory sounds and/or trouble breathing at least once a week . -
pubmed
[ Determination of sero- and biovariants of foreign and Soviet
strains of
Yersinia enterocolitica ] . -
pubmed
The results of the typing of the biochemical and serological variants of
Yersinia enterocolitica strains from the USSR ( 10
strains ) and other countries ( 32
strains ) are presented . -
pubmed
Malignant hepatomas induced in the
rat by
N - Nitrosomorpholine showed an absence of
trisialogangliosides GT1 and , in some cases , also a decrease in
disialoganglioside GD1a and
monoganglioside GM1 . -
pubmed
Effect of acid on the motility of the oesophagus of the
pig with experimentally induced
oesophagitis . -
pubmed
The mucous membrane of the oesophagus of 6
pigs was experimentally damaged with
hydrochloric acid to create changes similar to
reflux oesophagitis . -
pubmed
The passage of contrast medium through the oesophagus of the
pigs was observed by using
spot radiography and pressure measurements . -
pubmed
The uptake of
tryptophan and
tyrosine by the brain has been studied in 6
manic -
depressive patients and in 8
schizophrenics . -
pubmed
Chloramphenicol is presently the drug of choice in the initial treatment of serious
infections due to
Hemophilus influenzae type b. -
pubmed
A total of 160
strains of
H. - pubmed
In tests conducted on
mice and
rats with transplantable
tumours the antineoplastic activity of the racemic agent
D , L-1,4 - dibromo-1 , 4 - didesoxy-2 , 3 - butandiol is shown . -
pubmed
With chronic administration of the drug in subtherapeutic and therapeutic doses a higher leucocytes count was in evidence in the blood of the
animals with and without
tumours . -
pubmed
Subcutaneous transplantation of
EL4 lymphoma cells within
C57BL10 mice evoked an oedematous inflammatory response involving increased leukopoiesis within the bone marrow , a
blood leukocytosis , an influx of leukocytes into the transplants and surrounding host connective tissues , and extensive remodelling of surrounding host connective tissues involving
fibroplasia and angiogenesis . -
pubmed
Dexamethasone not only significantly reduced the numbers of circulating blood leukocytes within
C57BL10 mice bearing the subcutaneous EL4
lymphoma transplants , but also reduced the oedematous inflammatory response to the transplants . -
pubmed
The decreased influx of inflammatory leukocytes into the site of EL4
lymphoma cell transplantation within the
dexamethasone - treated
mice , was accompanied by reduced growth of the transplants . -
pubmed
In a multicentre phase II trial , 20
patients with advanced
pancreatic carcinoma were treated with
5 - fluorouracil ,
4 - epidoxorubicin and
mitomycin C , in which 4 -
epidoxorubicin was administered by escalated dose and split course ( FEM II ) . -
pubmed
In a prospective study 140 unselected
patients with clinical evidence of benign
adenoma of the prostate were resected via a transurethral approach . -
pubmed
T0
tumors were found in 11.5 versus 5.2 % of the
patients . -
pubmed
Determination of basal tear turnover in
insulin - dependent diabetes mellitus patients by fluorophotometry . -
pubmed
The tear turnover was determined by fluorophotometry in 25
insulin - dependent diabetes mellitus (
IDDM )
patients without
retinopathy and 29
IDDM patients with ( pre-)proliferative
retinopathy . -
pubmed
The results were compared with those in 34 healthy controls , to investigate the lacrimal gland function in
diabetic patients . -
pubmed
The tear turnover values in both
patient groups did not correlate significantly with age or
diabetes duration ( linear correlation coefficients : r less than 0.3 ) . -
pubmed
The tear turnover values in
patients both without
retinoplathy and with ( pre-)proliferative
retinopathy did not differ significantly from those in healthy controls ( mean + /- SD in % /min : 13.7 + /- 4.5 , 14.7 + /- 5.8 and 15.5 + /- 5.1 , respectively ; P greater than 0.16 ) . -
pubmed
The tear turnover values correlated significantly with the HbA1c and Schirmer - test values in
patients with ( pre-)proliferative
retinopathy ( r = 0.7 and r = 0.4 , respectively ; P less than 0.02 ) and with the blood
glucose values in
patients without
retinopathy ( r = 0.41 , P = 0.04 ) . -
pubmed
Since the tear turnover was not significantly decreased in
IDDM patients in comparison with healthy controls the
corneal disorders which are more frequently seen in these patients than in a healthy population may not be attributed to a decrease in tear production . -
pubmed
Workshop on the qualitative and quantitative comparability of
human and
animal developmental
neurotoxicity : summary and implications . -
pubmed
The Workshop on the Qualitative and Quantitative Comparability of
Human and
Animal Developmental Neurotoxicity was convened by the U.S. Environmental Protection Agency ( EPA ) and the National Institute on Drug Abuse to address issues related to when testing should be required , what test methodologies should be required , and how the data should be interpreted and applied to the risk assessment process . -
pubmed
The background material for Work Group discussions included presentations made at the Workshop by invited experts summarizing qualitative and quantitative
human and experimental
animal data on specific chemicals or classes of chemicals and
EPA 's proposed developmental
neurotoxicity testing protocol . -
pubmed
This overview : 1 ) summarizes the qualitative comparisons presented at the Workshop and attempts to make some quantitative comparisons of findings across
mammalian species following exposure to developmental neurotoxicants , 2 ) brings the common themes that were discussed among the Work Groups together into a regulatory perspective , 3 ) provides a status report on EPA 's developmental
neurotoxicity protocol , and 4 ) identifies research needs in the development of test methodologies and improvement of risk assessments for developmental neurotoxicants . -
pubmed
Prevention of
coccidiosis in the
chukar partridge (
Alectoris chukar ) by medication with
sulfadimethoxine and
ormetoprim (
Rofenaid ) . -
pubmed
Rofenaid ( a 5:3 mixture of
sulfadimethoxine and
ormetoprim ) was effective in preventing
coccidiosis of
chukar partridges . -
pubmed
Rofenaid should , therefore , be an effective medication for the prevention of
coccidiosis in
chukars in the field . -
pubmed
Oral
sotalol was given to 64
patients ( 78 % postinfarction ) with recurrent , reentrant
ventricular tachycardia (
VT ) during an average follow - up period of 19.7 months . -
pubmed
Fifty - nine ( 92 % )
patients had previously experienced recurrent
ventricular tachycardia , in spite of having received an average of three conventional antiarrhythmic drugs ( 13 had previously failed on other Class III drugs ) . -
pubmed
Sotalol failed in five
patients and was discontinued in six
patients because of severe side effects ( three
proarrhythmic effects , including two with
torsades de pointes)--a total of 18 % . -
pubmed
Dual chamber pacing was required by 11
patients because of poorly tolerated
bradycardia , and 14
patients remained symptomatic from worsening of the
cardiac failure in spite of pacing , increased diuretics , or vasodilator therapy . -
pubmed
Impaired pump function in the
patient with
congestive heart failure can arise from both contraction ( inotropic ) and relaxation ( lusitropic ) abnormalities . -
pubmed
The relative contributions of inotropic and lusitropic abnormalities to clinical disability differ in individual
patients with
heart failure , so that therapy of
heart failure must be tailored to the specific pathophysiology that operates in each patient . -
pubmed
A screening method aimed at identifying potential
human carcinogens using either animal
cancer bioassays or short - term genotoxic assays has 4 possible results : true positive , true negative , false positive and false negative . -
pubmed
In 112
patients with symptoms from
Paget ' s disease , 527 lesions were classified . -
pubmed
Prolonged treatment with
disodium etidronate led to progressive
osteopenia in 11
patients . -
pubmed
The UM - X7.1
myopathic and control
hamsters at 40 , 120 and 280 days of age were employed for the examination of heart sarcolemmal
Ca2 + -transport activities . -
pubmed
Na +-dependent
Ca2 + uptake activities were significantly depressed in
myopathic animals at 120 and 280 days of age in comparison to the control values . -
pubmed
It is suggested that a depression in the sarcolemmal
Ca2 + transport activities may contribute to the development of intracellular
Ca2 + overload in the genetically determined
cardiomyopathy in
hamsters and such a defect may be due to excessive amount circulating
catecholamines in these
animals . -
pubmed
In vivo , the compounds produced variable hypocholesterolemic and/or
hypotriglyceridemic effects when injected into groups of newly weaned
rats fed standard chow , high fat or high
carbohydrate diets . -
pubmed
Lymphocytapheresis in a
patient with severe
aplastic anemia . -
pubmed
A 17 - year - old Japanese
boy with severe
aplastic anemia was treated with
oxymetholone and
prednisolone for 9 weeks without improvement . -
pubmed
There is considerable variation in the substitution rate among different genes , and the rate seems to be lower in nonhuman viral
strains than in
human strains . -
pubmed
[ Autoradiographic study of the proliferative activity of bone marrow , spleen and liver cells in healthy
mice and in
mice with Rauscher virus - induced
erythroleukemia ] . -
pubmed
A variant of compensated
cardiogenic shock occurring in
patients with chronic
congestive heart failure following an episode of
pulmonary edema , and in the absence of
hypotension , is described . -
pubmed
In 55
patients with persistent
sinus bradycardia who underwent an electrophysiologic study of
sinus node , both in the basal state and after autonomic blockade (
propranolol , 0.2 mg / kg , and
atropine , 0.04 mg / kg ) , an
atropine test ( 0.02 mg / kg ) was performed the following day . -
pubmed
These data evidence that the
atropine test is not very helpful in discriminating between an organic and an autonomic involvement of
sinus automaticity in
patients with
sinus bradycardia . -
pubmed
Using special methods the authors examined the general sensitivity in clinically healthy pre - school
children ( 5 - 7 years ) in comparison with the results of examination of clinically normal adults ( 18 - 20 years ) and patients with different levels and nature of
foetal damage to the brain . -
pubmed
for description of upper extremity function after
stroke were compared by parallel assessments in a consecutive series of 50
patients with
hemimotor deficit . -
pubmed
Cephaloglycine as a urinary antimicrobial in
patients with
reduced renal function . -
pubmed
Metabolic changes with exercise in
patients with
hypopituitarism . -
pubmed
Circulating TGI has been observed in
patient with " simple "
goitre ,
Graves ' disease and more rarely in
Hashimoto ' s thyroiditis . -
pubmed
,
LY104119 reduced the
body weight of Avy / a
mice without altering the food consumption . -
pubmed
When slightly overweight a / a
mice were treated with
LY104119 in the diet , they lost weight , but a similar treatment of normal - weight a / a
mice caused a loss of only a small amount of carcass
triacylglycerol without affecting the
body weight . -
pubmed
Clot adherence to peritoneal cavity mesothelium was studied in
rats in an attempt to contribute to the problem of
thrombus embolization . -
pubmed
Thirty
patients ranging in age from 11 to 32 years were treated for
acne or
keratosis pilaris , using a new
polyester sponge for facial epidermabrasion . -
pubmed
Hemodynamic effects of
sodium nitroprusside in
patients with
ventricular septal defect . -
pubmed
During routine cardiac catheterization of ten
patients with
ventricular septal defect , the hemodynamic parameters were measured in the resting state and during
sodium nitroprusside infusion at an average rate of 8 micrograms / kg / min . -
pubmed
The favourable effect was most pronounced in
patients who had
pulmonary arterial hypertension in addition to elevated left ventricular filling pressures . -
pubmed
Patients without
pulmonary arterial hypertension showed an increase in the magnitude of left to right shunt . -
pubmed
The present study strongly indicates the need for further investigations utilizing orally effective vasodilators in
patients with
congestive heart failure due to left to right shunts . -
pubmed
Ion transport across the jejunum in normal and
cystic fibrosis mice . -
pubmed
Both the
erbA IRES and the
erbA / myb IRES virus constructs transformed erythroid cells after
infection of bone marrow or blastoderm cultures . -
pubmed
Surprisingly , when injected into
chicken embryos in the presence of helper virus , both viruses induced an
erythroleukemia in about half of the animals . -
pubmed
The average latency of
leukemia induction was shorter for the
erbA / myb IRES virus ( 3.5 weeks ) than for the
erbA IRES virus ( 5 weeks ) . -
pubmed
Developmental arrest of fertilized eggs from the B6.YDOM sex - reversed female
mouse . -
pubmed
When the Y chromosome of a
Mus musculus domesticus
mouse strain is placed onto the C57BL/6J ( B6 ) inbred background , the XY progeny develop ovaries or ovotestes but never normal testes during fetal life . -
pubmed
Between 1988 and 1990 , we examined fresh / frozen samples from 49
patients who had histologically confirmed
adenocarcinomas of the bilio - pancreatic carrefour : They had 23
cancers of the pancreas , 21 of the Vater 's papilla , and 5 of the common bile duct . -
pubmed
When the
affected organ was considered , a statistically significant difference in survival was observed : At 88 wk , survival was 0 % for
pancreatic and common bile duct cancer patients , and 18.2 % at 175 wk for Vater 's papilla
cancer patients ( p = 0.04 ) . -
pubmed
PURPOSE :
Bronchioloalveolar cell adenomas (
BAAs ) have been described in up to 10 % of
patients with
bronchogenic carcinoma . -
pubmed
METHODS : Follow - up information for a mean of 30 months was obtained on 28
patients with a single primary
bronchogenic carcinoma and one or more coexistent
BAAs . -
pubmed
RESULTS : There was no significant difference between percentage survival of
patients with a primary
bronchogenic carcinoma and coexistent
BAAs when compared with the percentage predicted survival of these
patients based on their primary
bronchogenic carcinoma alone . -
pubmed
CONCLUSIONS : On standard preoperative imaging for
bronchogenic carcinoma ,
BAAs were retrospectively detected in more than one third of
patients in whom they were detected pathologically . -
pubmed
UNLABELLED : We assessed the therapeutic benefits of 131I treatment in
patients with distant
metastases of
differentiated thyroid carcinoma . -
pubmed
METHODS : Of 2200
patients treated for
differentiated thyroid carcinoma at our institution , 394 had lung and/or bone
metastases . -
pubmed
RESULTS : Two - thirds of the
patients had
131I uptake in their
metastases , but only 46 % achieved a complete response . -
pubmed
The present study clearly demonstrates , however , that treatment with 131I is one of the factors which accounts for survival ;
patients whose
metastases concentrated 131I and who could be treated with
radioiodine had higher survival rates . -
pubmed
Other batches of
silicone oil or paraffin oil permitted development from the zygote to the blastocyst of an outbred
strain of
mouse without arrest at the 2 - cell stage . -
pubmed
This article reviews the effects of aging and
hypertension on geometrical ( lumen and arterial wall thickness ) and functional ( distensibility ) properties of large and medium - sized arteries in
humans . -
pubmed
We report such an association in a 48 - year - old
woman with several relatives suffering from
MEN 2A. -
pubmed
Treatment with topical
capsaicin , which has been shown to be effective in
notalgia paraesthetica , was not useful in our
patient . -
pubmed
The aim of the study was to quantify the presence in an abattoir and meat processing plant of risk factors represented by repetitive movements requiring the use of force , and to describe the work - related
musculo - skeletal disorders (
WMSDs ) of the upper limbs found in a group of
workers exposed to such risk factors . -
pubmed
Intestinal complications were recorded and groups of
animals were euthanized at 2 and 26 weeks to assess subacute and
chronic injury . -
pubmed
Extensive MR signal change in the craniad spinal cord parenchyma was found to be an ancillary sign of disease advancement in three
patients with clinically progressive posttraumatic
syringomyelia . -
pubmed
Sensitivities of
peptostreptococci ,
streptococci ,
Actinomyces , bacteroid , and
fusobacterial strains pathogenic for the periodontium to wide - spectrum
penicillines ,
cephalosporines ,
lincomycin ,
macrolides ,
metronidasole , and
nitasole are compared . -
pubmed
The mechanisms involved in mediating the enhanced gastric epithelial cell apoptosis observed during
infection with
Helicobacter pylori in vivo are unknown . -
pubmed
In addition to stimulating apoptosis ,
infection with
H. - pubmed
The failure to treat
actinic keratoses may have serious consequences for the
patient . -
pubmed
Biologic variables in the outcome of stages I and II
neuroblastoma treated with surgery as primary therapy : a
children 's
cancer group study . -
pubmed
CONCLUSION :
Children with stages I and II
neuroblastoma have 98 % survival with surgery alone as primary therapy . -
pubmed
Semiinvasive
pulmonary aspergillosis in
chronic obstructive pulmonary disease : radiologic and pathologic findings in nine
patients . -
pubmed
OBJECTIVE : The purpose of this study is to assess the radiographic , thin - section CT , and histologic findings of semiinvasive
aspergillosis in
patients with
chronic obstructive pulmonary disease (
COPD ) . -
pubmed
MATERIALS AND METHODS : The study included nine
patients with
COPD seen at the Hospital de Sant Pau during a 3 - year period who had histopathologically proven
aspergillosis with tissue invasion . -
pubmed
RESULTS : Nine
patients had semiinvasive
aspergillosis proven at autopsy ( n = 7 ) or by thoracoscopically guided lung biopsy ( n = 2 ) . -
pubmed
Cavitation was present in two of the
patients with consolidation and in two of the
patients with nodular opacities . -
pubmed
In the three
patients with multiple cavitated nodules , a variable degree of central
necrosis was observed . -
pubmed
CONCLUSION : Upper lobe consolidation or multiple nodules in
patients with
COPD should raise the possibility of semiinvasive
aspergillosis . -
pubmed
[ Effect of diet therapy and increased physical activity on risk factors for
atherosclerosis in
obese patients with
ischemic coronary heart disease ] . -
pubmed
CONCLUSIONS : This study supports assumption that hypocaloric diet and physical training can improve outcome of
patients with
coronary heart disease by influencing risk factors of
atherosclerosis . -
pubmed
Daily interruption of sedative infusions in
critically ill patients . -
pubmed
Multicenter phase II trial of
temozolomide in
patients with
glioblastoma multiforme at first
relapse . -
pubmed
PATIENTS AND METHODS : We report an open - label , uncontrolled , multicenter phase II trial of
temozolomide in 138
patients ( intent - to - treat [ ITT ] population ) with
glioblastoma multiforme at first
relapse and a Karnofsky performance status ( KPS ) & gt ; or = 70 . -
pubmed
One hundred twenty - eight
patients were histologically confirmed with
GBM or
gliosarcoma (
GS ) by independent central review . -
pubmed
CONCLUSIONS :
Temozolomide demonstrated modest clinical efficacy , with an acceptable safety profile and measurable improvement in quality of life in
patients with recurrent
GBM . -
pubmed
Selective
norepinephrine reuptake inhibition as a
human model of
orthostatic intolerance . -
pubmed
Vasovagal reactions occurred in 9
subjects on placebo and in 1 subject on
reboxetine . -
pubmed
This observation supports the hypothesis that disordered
norepinephrine uptake mechanisms can contribute to
human cardiovascular disease . -
pubmed
UNLABELLED :
Hepatitis C virus (
HCV ) has cytopathogenic effect not only on hepatocytes , however on salivary glands , monocytes of peripheral blood and lymphoid cells , may explain the systemic manifestations of the
infection . -
pubmed
HCV activates B and T - cells , modifies the immune response , causes lymphoproliferation , leading the development of
B - cell non - Hodgkin ' s lymphoma (
NHL ) . -
pubmed
PATIENTS AND METHODS : IgH gene rearrangements were examined from the sera of 57 chronic
HCV infected patients and 11
HCV - positive
cryoglobulinemic patients as well . -
pubmed
CONCLUSIONS : These results support the hypothesis that IgH gene rearrangement in
HCV positive patients can indicate the
lymphoproliferative disorder in the
HCV infection released B - cell proliferation and
lymphoma development . -
pubmed
An improved understanding of these mechanisms may be helpful in creating effective treatment programs for
children with
obesity . -
pubmed
Hallucinations and
delusions improved significantly in all
patients . -
pubmed
Donezepil was overall well tolerated , but a deterioration in
motor disability was noted in 2 out of 8
patients . -
pubmed
Univariate analysis indicated that there was a statistically significant difference in survival between the
patients with
alpha beta cutaneous T - cell lymphoma and
patients with
gamma delta cutaneous T - cell lymphoma ( P & lt;.0001 ) . -
pubmed
Among those
patients with
cutaneous gamma delta T - cell lymphoma ( n = 33 ) , there was a trend for decreased survival for
patients who had histologic evidence of subcutaneous fat involvement in comparison with
patients who had epidermotropic or dermal patterns of infiltration ( P = .067 ) . -
pubmed
To review and report our experience in eight
patients with maxillofacial
osteosarcomas , we retrospectively reviewed eight
patients with high - grade maxillofacial
osteosarcoma seen over the last decade at our institution . -
pubmed
METHODS : Blood pressure responses to shifts in salt intake were measured in 274
individuals with essential
hypertension in steady - state
sodium balance on high ( 200 mEq ) and low ( 10 mEq )
sodium intakes . -
pubmed
The aim of this study was to investigate the effects of
DA-8159 on penile erection in conscious and
acute spinal cord injured ( ASCI )
rabbits . -
pubmed
RESULTS :
DA-8159 induced a dose - dependent penile erection in both the conscious and
ASCI rabbits . -
pubmed
CONCLUSION : These results demonstrate that
DA-8159 may be a useful treatment option for
erectile dysfunction in
patients with or without a
spinal cord injury , but further evaluation of the effects of
DA-8159 on
humans must be performed . -
pubmed
A retrospective chart review was performed on 130
patients from the Ohio State University
Memory Disorders Clinic to examine the long - term effects of combination therapy with
donepezil and
vitamin E on
patients with
Alzheimer disease . -
pubmed
Patients declined at a significantly lower rate as compared with the Consortium to Establish a Registry for
Alzheimer ' s Disease data . -
pubmed
The long - term combination therapy of
donepezil and
vitamin E appears beneficial for
patients with
Alzheimer disease . -
pubmed
OBJECTIVES : To illuminate the current methodological and conceptual pitfalls inherent in conducting functional magnetic resonance imaging ( fMRI ) research with
individuals who have sustained
traumatic brain injury (
TBI ) and to discuss appropriate remedies . -
pubmed
We present the unusual occurrence of multiple systemic and two
central nervous system tuberculomas in an immunocompetent young
patient . -
pubmed
Cultures of the specimens yielded a mixed
infection with Corynebacterium species and
Staphylococcus epidermidis . -
pubmed
One of the hallmarks of
patients with
glioblastoma multiforme (
GBM ) is profound
lymphopenia mostly confined to the T cell lineage . -
pubmed
A deficiency in the production of naive T cells from the thymus could contribute to the
lymphopenia seen in
GBM patients . -
pubmed
Detection of
Trypanosoma cruzi and
Trypanosoma rangeli infection by duplex PCR assay based on telomeric sequences . -
pubmed
A 57 - year - old
woman was admitted because of severe
bradycardia and
hypotension caused by an anti -
arrhythmic agent and beta - blocker . -
pubmed
RESULTS : A male patient , white , 2 years - old , suffered multiple
stings of small red ants of the species
Solenopsis invictas , with the occurrence of severe
anaphylactic reactions , and resulting in cortical
blindness as a neurological sequel . -
pubmed
Vascular calcification is highly correlated with
cardiovascular disease (
CVD ) and is a significant predictor of cardiovascular events , especially in high risk
patients such as the
end stage renal disease (
ESRD ) population . -
pubmed
MATERIALS AND METHODS : A comprehensive number of four operators from 3 hospitals evaluated 57 consecutive
patients with 60 focal
hepatic lesions ( 28
hepatocellular carcinomas , 11
metastases , 13
hemangiomas , 1
hepatocellular adenoma and 7
focal nodular hyperplasias ) by baseline gray - scale ultrasound ( US ) and color Doppler US . -
pubmed
Making a pre - operative diagnosis allows the neurosurgeon to be confident in the choice of treatment plan for the
patient and
allays considerable
patient anxiety . -
pubmed
[ Out - of - body experience as possible
seizure symptom in a
patient with a
right parietal lesion ] . -
pubmed
We report a 44 - year - old
patient with
epigastric auras , psychomotor and grand mal
seizures , and
paroxysmal experiences during which he believed to have left his body and seen himself from the outside . -
pubmed
Following extirpation of the lesion , the
patient has been
seizure - free for 5 years . -
pubmed
A meta - analysis of the relationship of child
sexual abuse to
HIV risk behavior among women . -
pubmed
OBJECTIVE : This study is a meta - analysis of the literature exploring the relationship between
child sexual abuse (
CSA ) and
HIV risk behavior among women . -
pubmed
Persistent high - level
BKV replication is the hallmark of polyomavirus - associated
nephropathy in renal transplantation and of
hemorrhagic cystitis in bone marrow transplantation . -
pubmed
The role of
BKV in
autoimmune disease and
cancer is a controversial topic and is difficult to determine , because the pathology no longer depends on
BKV replication . -
pubmed
We reviewed our experience to investigate the determinants of
paraplegia after stent - graft repair of the thoracic aorta , identify
patients at risk , and assess the effectiveness of ancillary techniques . -
pubmed
Indications for treatment were
atherosclerotic aneurysms in 88
patients , chronic type B dissection in 10
patients , and penetrating
aortic ulcer in 5
patients . -
pubmed
Four of the 103
patients affected with
thoracoabdominal aortic aneurysms had hybrid procedures and were excluded from the cumulative analysis . -
pubmed
Twelve
patients with zone 0 and zone 1
aortic arch aneurysms were operated on with synchronous or staged surgical aortic debranching . -
pubmed
Neurologic deficits were assessed by an independent
neurologist and classified as immediate or delayed . -
pubmed
Four
patients ( 4.04 % ) had delayed
neurologic deficit that completely resolved after the institution of CSF drainage ,
steroids administration , and arterial pressure pharmacologic adjustment . -
pubmed
None of the four
patients who underwent hybrid procedures for
thoracoabdominal aortic aneurysms had
paraplegia or
paraparesis . -
pubmed
Percentage of
hepatitis C virus - infected hepatocytes is a better predictor of response than serum
viremia levels . -
pubmed
An integrated analysis of thirteen trials summarizing the long - term safety of alefacept in
psoriasis patients who have received up to nine courses of therapy . -
pubmed
OBJECTIVE : The aim of this work was to further examine the safety profile of alefacept by integrating data from clinical trials involving
patients with
chronic plaque psoriasis who received up to 9 courses of therapy over a 5 - year period . -
pubmed
METHODS : Data from 13 clinical trials conducted in
patients with
plaque psoriasis were integrated because they had similar inclusion / exclusion criteria and assessments . -
pubmed
CONCLUSIONS : This integrated analysis of data from 13 trials with 1869
patients supports the safety and tolerability of alefacept for longer - term treatment of
psoriasis . -
pubmed
According to the last IKDC evaluation , 7
patients ( 58.33 % ) were graded A , 4
patients ( 33.3 % ) B , and 1 patient ( 8.33 % ) C. Except for 1
patient who complained of mild
pain at the donor site of the contralateral healthy knee , no patients complained of donor - site morbidity or dysfunction of the healthy leg . -
pubmed
Because inclusion of
PCB - contaminated fish , which comprised approximately 1 % of the diet , resulted in mandibular and maxillary squamous cell proliferation , it is possible that consumption of up to 30 - fold that quantity of HR fish , as could be expected for wild
mink , would result in more severe lesions characterized by
loss of teeth , thus impacting survivability . -
pubmed
[ Long - term effects of early hyperbaric
oxygen therapy on neonatal
rats with
hypoxic - ischemic brain damage ] . -
pubmed
This study was designed to evaluate the long - term pathological and behavioral changes of early
HBO therapy on neonatal
rats with
HIBD . -
pubmed
RESULTS : The
rats in the HIBD group displayed significant morphological and histological deficits , as well as severe spatial
learning and memory disability . -
pubmed
RESULTS : Among 637
patients with biopsy - proven
GN included in this study , 88 ( 13.8 % ) had glomerular crescent formation . -
pubmed
Among them , pauci - immune crescentic
glomerulonephritis (
PICGN ) ( 42
patients , 47.2 % ) and
lupus nephritis ( 25
patients , 28.4 % ) were the most common pathologic diagnoses . -
pubmed
Lupus
patients were younger ( p = 0.028 ) , while PICGN
patients had more chronic lesions ( p & lt ; 0.001 ) , extensive glomerular crescents ( p & lt ; 0.001 ) , less severe
proteinuria ( p & lt ; 0.001 ) and poorer renal survival ( p = 0.0017 ) . -
pubmed
When injected into newborn
mice , the glutamatergic analogue ,
ibotenate , produces
cortical lesions and
white matter cysts that mimic
human perinatal
brain lesions . -
pubmed
This is true for both
herpes simplex virus type-1 and
herpes simplex virus type-2 . -
pubmed
Seizure prophylaxis in an
animal model of
epilepsy by dietary
fluoxetine supplementation . -
pubmed
The present studies tested the possibility that the El
mouse model of genetically predisposed / handling - triggered
epilepsy would exhibit fewer
seizures following
SSRI treatment via dietary
fluoxetine adulteration . -
pubmed
El
mice consuming a chow diet ad libitum or yoked in quantity to
fluoxetine diet intake exhibited
seizure incidence of 40 % in response to tail - suspension handling , whereas
seizures were abolished ( 0 % ) among El
mice consuming a
fluoxetine - adultered diet over 7 days . -
pubmed
Taken together , these results suggest that dietary
fluoxetine supplementation abolishes handling - induced
seizure susceptibility in El
mice via a neural remodeling mechanism independent of energy balance . -
pubmed
METHODS :
CCl4 , 0.5 mL / kg
body weight , was injected into the peritoneum of C57BL/6
mice twice a week for 5 wk . -
pubmed
Although very few ES - derived cells were demonstrated immunohistologically in the livers of group 1
mice on PD 30 , improvements in
liver fibrosis were observed . -
pubmed
Unexpectedly ,
liver tumor formation was not observed in any of the
mice that received ES cell transplantation during the experimental period . -
pubmed
An intervention for
manic or mixed symptomatology was required in 27
patients , whereas 22
patients were treated for
depressive symptoms . -
pubmed
OBJECTIVE : To estimate the prevalence of the
hepatitis C virus (
HCV ) and
HIV infection and associated risk behaviors among injection drug users ( IDUs ) in two northern Mexican cities . -
pubmed
Batrachochytrium dendrobatidis infection was identified in 64 % of the
R. - pubmed
sphenocephala larvae might be resistant to
infection , even when occupying the same wetland as the infected
R. - pubmed
Kidney transplantation is the treatment of choice for
patients with
ESRD . -
pubmed
Other factors , including
cardiovascular disease ,
infections , and
malignancies , also shorten
patient survival and therefore reduce the functional life of an allograft . -
pubmed
Therefore , interventions need to address
disease progression , comorbid conditions , and
patient mortality through a multifaceted approach . -
pubmed
In the last 25 years ,
human immunodeficiency virus (
HIV ) has become the leading infectious killer of adults globally , with an estimated 44 million people infected with the virus worldwide . -
pubmed
Evaluation of the need for endoscopy to identify low - risk
patients presenting with an acute
upper gastrointestinal bleed suitable for early discharge . -
pubmed
METHODS : All
patients with low - risk acute upper GI
bleeding presenting to two separate hospital sites in Leeds from August 2002 to March 2005 were identified . -
pubmed
None of the 194
patients had further
bleeding or complications within 30 days . -
pubmed
CONCLUSIONS :
Patients admitted with a low - risk acute upper
GI bleeding can be managed safely by a nurse - led process - driven protocol , based on readily available clinical and laboratory variables , with early discharge & lt;24 h. Avoiding in - patient endoscopy appears to be safe but at the price of greater clinic follow - up . -
pubmed
Sleeping hearts : the role of the heart in
sleeping sickness (
human African
trypanosomiasis ) . -
pubmed
OBJECTIVES : To estimate the frequency and evolution of heart involvement in
human African
trypanosomiasis (
HAT ) using electrocardiogram ( ECG ) findings ; to describe these findings and to assess the frequency and clinical relevance of
symptoms and signs before and after treatment . -
pubmed
RESULTS : Major ECG alterations were significantly more frequent in
HAT patients than in healthy controls ( 71%vs . -
pubmed
The median NT - proBNP was significantly higher in
HAT patients than in controls ( 85.2 vs. 28 pg / ml ; P & lt ; 0.001 ) . -
pubmed
CONCLUSIONS : Cardiac involvement documented by ECG alterations is common in
HAT patients , but
cardiopathy rarely causes severe
congestive heart failure and subsides after treatment . -
pubmed
Electromyographic characterization in an
animal model of
dystonia . -
pubmed
Kernicterus is known to produce damage to the auditory system and the basal ganglia in
humans . -
pubmed
Although the Gunn
rat model of
kernicterus has been extensively used to characterize the auditory features , this model has not been similarly utilized to systematically investigate the
movement disorder . -
pubmed
In the present study , spontaneously jaundiced ( jj ) 16 day old Gunn
rat pups were treated with
sulfadimethoxine to exacerbate
bilirubin toxicity and compared to saline treated jjs and non - jaundiced ( Nj ) littermates . -
pubmed
Electromyographic ( EMG ) activity was recorded from antagonistic hip muscles in
dystonic and in normal appearing
rats . -
pubmed
Coherence plots of the separated signals coefficients revealed 4 - 7 Hz co - activation in antagonistic muscles that was significantly more prominent in
jj sulfa treated
dystonic compared to normal
rats . -
pubmed
The EMG findings support the presence of
dystonia in
sulfadimethoxine exposed jj Gunn
rats and suggest that these
animals can serve as a valuable model for experimental investigations of
dystonia . -
pubmed
DBDCT exhibited strong in vitro cytotoxic activity toward
human immature granulocyte leukemia ( HL-60 ) ,
human salivary - gland
carcinoma (
SGC-7901 ) ,
human henrietta carcinoma (
Hela ) and
human urinary bladder (
T24 ) cell lines which , in some cases , were equal to , or even higher than those of
cis - dichlorodiammineplatinum ( II ) (
cisplatin ,
DDP ) , the widely clinically used drug . -
pubmed
The further in vivo antitumor tests of
DBDCT towards the transplantation
tumor models of
sarcoma carcinoma ( S(180 ) ) ,
hepatocellular carcinoma ( H(22 ) ) and Ehrlich 's
ascites carcinoma (
EAC ) on
mice were carried out via injection intraperitoneally with
cisplatin as positive contrast drug . -
pubmed
RESULTS : Group C had significantly fewer
patients with
biliary tract disease , improper diet and heavy
alcohol consumption , and significantly more
patients with passed history of moderate - severe
hypertriglyceridemia than Group A and B ( P & lt ; 0.05 ) . -
pubmed
PSD increased the susceptibility of
mice to LPS - induced immobility in the open field , which was capable of affecting the
anxiety - like behavior also . -
pubmed
Injection of non - specific dsRNA initiates a broad - spectrum innate antiviral immune response in the
Pacific white shrimp ,
Litopenaeus vannamei , however , the receptor involved in recognition of this by - product of
viral infections remains unknown . -
pubmed
Furthermore , several experimental studies have shown that NTDs in embryos of
diabetic mice are associated with altered expression of genes , which control development of the neural tube . -
pubmed
Double - blind , placebo - controlled study to evaluate two
miconazole conditioners for the treatment of
Malassezia dermatitis in
dogs . -
pubmed
Eighteen
dogs with
Malassezia dermatitis participated in a clinical trial to evaluate the efficacy of
miconazole conditioners . -
pubmed
Investigators evaluated
erythema ,
pruritus , and
yeast counts weekly . -
pubmed
However , MMC
mice on the C3H background were susceptible to
arthritis also with a functional oxidative burst . -
pubmed
BACKGROUND : The purpose of this study was to assess the efficacy and
toxicity of biweekly
irinotecan plus
5 - fluorouracil ( FU ) and
leucovorin ( LV ) in
patients with relapsed or metastatic
colorectal cancer . -
pubmed
MATERIALS AND METHODS : Between March 2002 and May 2004 , 24
patients with histologically confirmed relapsed or metastatic
colorectal cancer were enrolled in this study . -
pubmed
CONCLUSION : The results suggested that
irinotecan ,
5 - FU and
leucovorin combination chemotherapy in a biweekly schedule is a practical and tolerable treatment option in
patients with advanced
colorectal cancer . -
pubmed
OBJECTIVE : To assess treatments and survival of
patients with
muscle invasive bladder cancer (
MIBC ) in the Comprehensive Cancer Center Northern Netherlands ( CCCN ) region . -
pubmed
A
patient presented with a
superior sulcus tumor situated anterior in the thoracic inlet . -
pubmed
Quality of life in patients with
vitiligo : a descriptive study on 83
patients attending a PUVA therapy unit in Imam Reza Hospital , Mashad . -
pubmed
BACKGROUND : Several meta - analyses indicate that there is an inverse genetic correlation between
ethanol preference drinking and
ethanol withdrawal severity , but limited work has characterized
ethanol consumption in 1 genetic
animal model , the Withdrawal
Seizure - Prone ( WSP ) and - Resistant ( WSR )
mouse lines selected for severe or mild
ethanol withdrawal , respectively . -
pubmed
RESULTS : Withdrawal
Seizure - Prone-1
mice consumed more
ethanol than WSR-1
mice under a fixed ratio ( FR)-4 schedule as
ethanol was faded into the
sucrose solution , but this line difference dissipated as the
sucrose was faded out to yield an unadulterated 10 % v / v
ethanol solution . -
pubmed
OBJECTIVE : To evaluate the clinical characteristics of
oropharyngeal dysphagia in
Machado - Joseph disease patients . -
pubmed
METHOD : Forty
individuals participated in this study , including 20 with no clinical complaints and 20 dysphagic
patients with
Machado - Joseph disease of clinical type 1 , who were all similar in terms of gender distribution , average age , and cognitive function . -
pubmed
At the end , the profile of
dysphagia in
patients with
Machado - Joseph disease was classified according to the Severity Scale of
Dysphagia , as described by O'Neil and collaborators . -
pubmed
RESULTS : Comparison between dysphagic
patients and controls did not reveal many significant differences with respect to the clinical evaluation of the oral phase of deglutition , since afflicted
patients only demonstrated deficits related to the protrusion ,
retraction and tonus of the tongue . -
pubmed
Dysphagic
patients presented pharyngeal stasis during deglutition of liquids and solids , accompanied by
coughing and/or choking as well as penetration and/or aspiration ; these signs were absent in the controls . -
pubmed
The
dysphagia of these
patients is classified between mild and moderate . -
pubmed
METHODS : Eight
patients ( three
males and five
females ) with stable
vitiligo qualified for the study . -
pubmed
CONCLUSIONS : Autologous minigrafts with ultrapulsed
carbon dioxide laser abrasion appear to have the potential to achieve complete repigmentation in
patients with stable
vitiligo who fail to respond to medical treatments . -
pubmed
Therapeutic benefit of Yangxue Qingnao Granule on
cognitive impairment induced by chronic
cerebral hypoperfusion in
rats . -
pubmed
METHODS : Adult male
Wistar rats were subjected to chronic
cerebral hypoperfusion by permanent occlusion of bilateral common carotid arteries ( 2 - VO ) . -
pubmed
Nicotinamide treatment protects pups against
intestinal injury incurred in the newborn
rat NEC model . -
pubmed
Previous studies have shown a protective effect of
glycine on this
toxicity in
rat hepatocytes ( Vance et al . -
pubmed
In the present study we investigated the
hepatoxicity of 1 - 4 mM
valproate in combination with
glycine through absorption of
neutral red from
human hepatoma cells (
Hep G2 ) in monolayer cell culture . -
pubmed
In conclusion a hepatoprotective effect of
glycine on
valproate - induced
toxicity is also given in
human hepatocytes . -
pubmed
Analysis of gut morphogenesis in
Shroom3 deficient mouse embryos revealed that the direction of gut rotation is also disrupted . -
pubmed
A number of
animal experiments have explored both acute and long - term
toxicity with respect to the lungs , the cardiovascular system , and the bladder , showing inflammatory and possible carcinogenic effects . -
pubmed
Affected
individuals often show a unique pattern of cognitive strengths and weaknesses and are at increased risk for a number of other
neurodevelopmental conditions , many of which are more common in typical males than typical females ( e.g. -
pubmed
Understanding the contribution of these different mechanisms to outcome has the potential to improve clinical care for
individuals with
TS and to better our understanding of the differential vulnerability to and expression of
neurodevelopmental disorders in males and females . -
pubmed
In this paper , we review what is currently known about cognition and brain development in
individuals with
TS , discuss underlying mechanisms and their relevance to understanding male - biased neurodevelopmental conditions , and suggest directions for future research . -
pubmed
Thus the
EBV - positive
HL could in the future prove to be an excellent candidate for targeted cellular immunotherapy . -
pubmed
Minor hepatic resection for
hepatocellular carcinoma in cirrhotic
patients : Kelly clamp crushing resection versus heat coagulative
necrosis with bipolar radiofrequency device . -
pubmed
Hemorrhage and
postoperative liver insufficiency are frequent and serious complications of hepatic resection in cirrhotic
patients . -
pubmed
We retrospectively reviewed the results of 35
patients who had undergone resection for monofocal
hepatocellular carcinoma at our center . -
pubmed
This nonrandomized retrospective study suggests that radiofrequency - assisted liver resection is associated with better results than the Kelly clamp crushing resection technique in cirrhotic
patients with focal
hepatocellular carcinoma and preserved liver function . -
pubmed
BACKGROUND : High levels of viable
Staphylococcus aureus , which are often found on inflamed skin surfaces , are usually associated with
atopic dermatitis . -
pubmed
No associations between levels of viral diversity within the non - structural genes and
HIV-1 RNA load during primary
infection were found . -
pubmed
Effect of
carvedilol and
nebivolol on oxidative stress - related parameters and endothelial function in
patients with essential
hypertension . -
pubmed
Vittatidera zeaphila ( Nematoda : Heteroderidae ) , a new genus and species of
cyst nematode parasitic on
corn (
Zea mays ) . -
pubmed
Intravenous administration of
human umbilical cord blood - mononuclear cells dose - dependently relieve
neurologic deficits in
rat intracerebral hemorrhage model . -
pubmed
Intravenously transplanted UC - MCs can accelerate the neurological function recovery of
ICH rat and diminish the striatum lesion size by demonstrating a dose relationship between them . -
pubmed
Hemiarthroplasty for humeral four - part
fractures for
patients 65 years and older : a randomized controlled trial . -
pubmed
QUESTIONS / PURPOSES : We therefore performed a randomized controlled trial to compare ( 1 ) function , ( 2 ) strength , and ( 3 )
pain and disability in
patients 65 years and older with four - part humeral
fractures treated either nonoperatively or with hemiarthroplasty . -
pubmed
Abduction strength was better at 3 and 12 months in the nonoperatively treated group although the nonoperatively treated
patients experienced more
pain at 3 months ; this difference could not be detected after 12 months . -
pubmed
CONCLUSIONS : We observed no clear benefits in treating
patients 65 years or older with four - part
fractures of the proximal humerus with either hemiarthroplasty or nonoperative treatment . -
pubmed
BACKGROUND : There are limited data comparing radiofrequency catheter ablation with antiarrhythmic drug therapy as first - line treatment in
patients with paroxysmal
atrial fibrillation . -
pubmed
METHODS : We randomly assigned 294
patients with paroxysmal
atrial fibrillation and no history of antiarrhythmic drug use to an initial treatment strategy of either radiofrequency catheter ablation ( 146
patients ) or therapy with class IC or class III antiarrhythmic agents ( 148
patients ) . -
pubmed
At 24 months , the burden of
atrial fibrillation was significantly lower in the ablation group than in the drug - therapy group ( 90th percentile , 9 % vs. 18 % ; P=0.007 ) , and more
patients in the ablation group were free from any
atrial fibrillation ( 85 % vs. 71 % , P=0.004 ) and from symptomatic
atrial fibrillation ( 93 % vs. 84 % , P=0.01 ) . -
pubmed
CONCLUSIONS : In comparing radiofrequency ablation with antiarrhythmic drug therapy as first - line treatment in
patients with paroxysmal
atrial fibrillation , we found no significant difference between the treatment groups in the cumulative burden of
atrial fibrillation over a period of 2 years . -
pubmed
METHODS : Twenty consecutive
patients treated by volar locking plate fixation for low - grade open DRFs constituted the open
fracture group , and 40
patients were selected from among the total number of
patients treated by volar , locking plate fixation for closed DRFs as the closed
fracture group . -
pubmed
Recurrent
SAH was defined as two or more discrete episodes of
SAH ( discriminant function>=32 ) coinciding with recidivism in the same
patient , with documented improvement / resolution of
jaundice during intervening periods of abstinence . -
pubmed
RESULTS : Of 56
patients with recidivism following index presentation with
SAH , 10 ( 17.9 % ) developed recurrent
SAH . -
pubmed
CONCLUSION : Approximately 18 % of
patients , especially women , develop recurrent
SAH because of recidivism , with increasing disease severity and mortality approaching 60 % . -
pubmed
METHODOLOGY AND RESULTS : In our modified
rat model of
NIC , a trapezoid - shaped
silicon rubber was inserted into the epidural space under the L5 and L6 vertebral plate . -
pubmed
vulgaris
infection and simultaneous occurrence of
Strongylus edentatus and Triodontophorus spp . -
pubmed
Vertebral augmentation in
patients with
multiple myeloma : a pooled analysis of published case series . -
pubmed
BACKGROUND AND PURPOSE : Studies examining the efficacy of vertebroplasty and kyphoplasty in
patients with
vertebral fractures from
multiple myeloma are limited . -
pubmed
We sought to perform a systematic review of published case studies examining changes in
pain , disability , and analgesic drug use in
patients with
multiple myeloma who have undergone vertebral augmentation . -
pubmed
MATERIALS AND METHODS : We performed a pooled analysis of published case series of vertebral augmentation in
patients with
multiple myeloma . -
pubmed
RESULTS :
Patients achieved a decrease in
pain across all consolidated time periods . -
pubmed
CONCLUSIONS : Our analysis demonstrates that vertebral augmentation is effective in
patients with
multiple myeloma . -
pubmed
Audiologic and vestibular assessment in
patients with
beta - thalassemia major receiving long - term transfusion therapy . -
pubmed
BACKGROUND : Life - long transfusion therapy with chelators is a treatment choice for
patients with
beta - thalassemia major . -
pubmed
PROCEDURE : Thirty - seven
patients with
beta - thalassemia major who received regular transfusion in our hospital were enrolled . -
pubmed
Sixteen
patients ( 80 % ) had canal
paresis in the caloric test . -
pubmed
CONCLUSIONS : The incidence of
auditory impairment and
vestibular dysfunction was high in
patients with
beta - thalassemia major receiving long - term transfusion therapy . -
pubmed
Since then , 12
patients with
AA have been treated with
TG . -
pubmed
Here , we summarize the effectiveness and safety of
TG in comparison with data from 14
AA patients treated with LG before April 2009 . -
pubmed
Infection was noted in five ( 38 % ) and four ( 33 % )
subjects treated with LG and
TG , respectively . -
pubmed
We conclude that
TG at a dose of 2.5 mg / kg / day for 5 days is effective and safe in Japanese
patients with
AA . -
pubmed
44 healthy
volunteers free from
postural and temporomandibular disorders . -
pubmed
Low - frequency , Repetitive Transcranial Magnetic Stimulation for the Treatment of
Patients with
Posttraumatic Stress Disorder : a Double - blind , Sham - controlled Study . -
pubmed
The aim of this study was to compare the effect of rTMS on the right prefrontal cortex with that of sham stimulation among
patients with
PTSD . -
pubmed
METHODS : In total , 18
patients with
PTSD were randomly assigned to the 1 - Hz low - frequency rTMS group or the sham group for 3 weeks . -
pubmed
Association of
25 - hydroxyvitamin D serum levels and metabolic parameters in
psoriatic patients with and without
arthritis . -
pubmed
OBJECTIVE : The objective was to assess the relationship of
25 - hydroxyvitamin D [
25 -( OH ) D ] levels with lipid and
glucose metabolism parameters in
psoriatic patients with and without
arthritis . -
pubmed
METHODS : We studied 122
patients with
psoriasis ( 61 without
arthritis and 61 with
arthritis ) from the
psoriasis unit ( dermatology department ) and rheumatology department of our hospital , analyzing lipid and
glucose metabolism variables and serum
25 -( OH ) D concentrations . -
pubmed
No association was found between serum
25 -( OH ) D levels and any metabolic parameter in the
patients with
psoriatic arthritis . -
pubmed
CONCLUSIONS : Serum
25 -( OH ) D was inversely related to lipid and
glucose metabolism parameters in
psoriatic patients without
arthritis , whereas no such association was observed in
psoriatic patients with
arthritis . -
pubmed
Interventional studies are warranted to assess the effects of
vitamin - D supplements on the metabolic profile of
psoriatic patients without
arthritis . -
pubmed
Effects of MLC601 on early vascular events in
patients after
stroke : the CHIMES study . -
pubmed
A complex
odontoma of the anterior maxilla associated with an erupting
canine . -
pubmed
We outline a list of major issues and also suggest some standardized procedures in collecting clinical and imaging data on major
depressed patients . -
pubmed
The authors describe the case of a 31 - year - old
woman presenting with
low - back and radicular pain without
weakness or bowel or
bladder dysfunction . -
pubmed
BACKGROUND / AIMS :
Bacterial translocation ( BT ) promotes microinflammation in predialysis
patients with
end - stage renal disease (
ESRD ) . -
pubmed
However , the change in BT has not been reported in
ESRD patients undergoing regular hemodialysis treatment . -
pubmed
METHODS : A prospective study was carried out in which adult
HIV-1 - infected patients who started mtDRV /
rtv after viral suppression for & gt;= 6 months with no major
darunavir - related resistance mutations were enrolled . -
pubmed
Patients with two consecutive plasma
HIV RNA measurements & gt;200
HIV-1 RNA copies / mL were considered as having virological failure (
VF ) , while patients with two consecutive plasma
HIV RNA measurements & gt;50 copies / mL without meeting the VF criteria were considered to have virological rebound ( VR ) . -
pubmed
Serum
8,12 - iso - iPF2alpha - VI isoprostane marker of oxidative damage and
cognition deficits in
children with konzo . -
pubmed
We sought to determine whether motor and
cognitive deficits associated with
cassava ( food )
cyanogenic poisoning were associated with high concentrations of
F2 - isoprostanes , well - established indicators of oxidative damage . -
pubmed
These findings suggest that
cognitive deficits and , possibly ,
brain injury associated with
cassava poisoning is mediated in part by oxidative damage in
children with konzo . -
pubmed
8,12 - iso - iPF2alpha - VI isoprostane appears to be a good marker of the neuropathogenic mechanisms of konzo and may be used to monitor the impact of interventional trials to prevent the
neurotoxic effects of
cassava cyanogenic poisoning . -
pubmed
Histoplasmosis caused by
Histoplasma capsulatum var . - pubmed
OBJECTIVE : Study of
pulmonary hypertension (
PAH ) during pregnancy has characteristics of the high risk factors for
patient death and its clinical characteristics . -
pubmed
RESULTS : ( 1 ) In 8
patients , 4 cases were
IPAH , none of them with primary diseases , and they were complicated with severe
tricuspid regurgitation . -
pubmed
(4 ) In 8
patients , 7 cases of median
death time were 3 days after delivery , including 4 cases of
IPAH patients death for 2.5 days after delivery ; the causes of
death were
PAH crisis and
heart failure . -
pubmed
( 5 ) In 8
patients , 1
patient with
CHD -
PAH secondary to
patent ductus arteriosus in gestational week 31
stillbirths occur . -
pubmed
( 2 ) Compared with the pregnant
women with
CHD-
PAH , faster progress and poor prognosis in
patients with
IPAH disease . -
pubmed
( 3)The
patients during cesarean operation or intrapartumare easy to cause PAH crisis and
heart failure or
multiple organ failure . -
pubmed
Taking active measures to maintain stability of hemodynamics is the key to prevent the occurrence of
death of pregnant
women with
PAH . -
pubmed
Chronic phalaris toxicity in
eastern grey kangaroos (
Macropus giganteus ) . -
pubmed
Zinc supplementation suppresses the progression of bile duct ligation - induced
liver fibrosis in
mice . -
pubmed
Hydrogen peroxide administered into the
rat spinal cord at the level elevated by
contusion spinal cord injury oxidizes proteins , DNA and membrane phospholipids , and induces cell
death : attenuation by a
metalloporphyrin . -
pubmed
H2O2 was perfused through a microcannula into the uninjured
rat spinal cord to mimic the conditions induced by
SCI . -
pubmed
Lithium remains the first line for the treatment and prophylaxis of
bipolar disorders , but currently available treatment alternatives for
lithium resistant
patients are of limited and/or questionable efficacy . -
pubmed
, a
mania followed by a
depression , in
rats . -
pubmed
In this study , we examined the innate immune potential of primary LEC populations derived from multiple tissues of an animal model for
human infectious diseases - the
ferret . -
pubmed
MATERIALS AND METHODS : This study is a retrospective chart review , and in this study , hospital records of 58
patients with biopsy proven
sinonasal malignancies were studied . -
pubmed
Impaired right ventricular hemodynamics indicate preclinical
pulmonary hypertension in
patients with
metabolic syndrome . -
pubmed
The contributions of
metabolic syndrome (
MetS ) and
obesity to
pulmonary hypertension and
right ventricular dysfunction in
humans remain unclear . -
pubmed
We investigated the association of
MetS and
obesity with right ventricular structure and function in
patients without
cardiovascular disease . -
pubmed
METHODS AND RESULTS : A total of 156
patients with
MetS ( mean age 44 years , 71 %
women , mean
body mass index 40 kg / m(2 ) ) , 45 similarly obese
persons without
MetS , and 45 nonobese controls underwent echocardiography , including pulsed wave Doppler measurement of pulmonary artery acceleration time ( PAAT ) and ejection time . -
pubmed
Hydrochlorothiazide - induced
tubulointerstitial nephritis in a
patient with
Dent disease . -
pubmed
Coagulase negative staphylococci and Enterobacteriaceae are the most frequent pathogens causing approximately 25 % of
BSI each , followed by enterococci ,
P. - pubmed
Weight change during long - term treatment with
lurasidone : pooled analysis of studies in
patients with
schizophrenia . -
pubmed
The objective of this analysis was to evaluate the effect of 12 months of treatment with
lurasidone on weight in
patients with
schizophrenia . -
pubmed
Weight gain of at least 7 % from study baseline was observed in 16.0 , 25.8 , and 15.2 % of
patients , and
weight loss of at least 7 % was seen in 18.5 , 6.7 , and 9.1 % of
patients treated with
lurasidone ,
risperidone , and
quetiapine XR , respectively . -
pubmed
A shift from normal /
underweight baseline
BMI status to
overweight /
obese at month 12 occurred in 10.2 , 27.6 , and 15.0 % of
patients in the
lurasidone ,
risperidone , and
quetiapine XR groups , respectively . -
pubmed
Conversely , 14.3 , 1.7 , and 7.7 % of
patients , respectively , shifted from
overweight /
obese to normal /
underweight . -
pubmed
In summary , a low potential for clinically significant
weight gain was observed in
patients with
schizophrenia treated continuously with
lurasidone for 12 months . -
pubmed
METHODS : From a well - defined population - based cohort of CBC -
patients , we have constructed a unique tissue - microarray including 600 pairs of primary
tumours and
CBCs . -
pubmed
Patients diagnosed with two high stage
tumours within a short time - interval had a particularly bad prognosis . -
pubmed
Treg / Th17 balance plays a critical role in maintaining immune homeostasis of
acute graft - versus - host disease (
aGVHD )
patients . -
pubmed
First report of a NDM - producing
Providencia rettgeri strain in the state of Sao Paulo . -
pubmed
Botrytis cinerea is the causal agent of
gray mold disease in various plant species and produces grayish macroconidia and/or black sclerotia at the end of the
infection cycle . -
pubmed
Pain is a major problem for Intensive Care Unit ( ICU )
patients . -
pubmed
Despite numerous improvements it is estimated that as many as 70 % of the
patients experience moderate - to - severe
postoperative pain during their stay in the ICU . -
pubmed
Minimizing
nausea ,
vomiting ,
urinary retention , and sedation may indeed facilitate
patient recovery and it is likely to shorten the ICU and hospital stay . -
pubmed
The results showed that mutant
strain ZJB12073 exhibited 1.9 - fold improvement in
echinocandin B production to 1656.3 + - 40.3 mg / L when compared with the parent
strain . -
pubmed
RESEARCH DESIGN AND METHODS : Renal tubular epithelial cells ( RTECs ) from
rat kidneys experiencing
HS and a cell line (
HK-2 ) under
hypoxia / reoxygenation ( H / R ) treatment were used . -
pubmed
RESULT : Severe
MD was found in
rat kidneys , especially in RTECs , as evidenced by swollen mitochondria and poorly defined cristae , decreased mitochondrial membrane potential ( DeltaPsim ) , and reduced
ATP content . -
pubmed
Reverse
takotsubo cardiomyopathy (
TCM ) is a less common variant of classic
TCM that presents within a different
patient profile and with its own hemodynamic considerations . -
pubmed
A 46 - year - old
woman was admitted to our hospital for laryngoscopy and possible balloon dilatation for
tracheal stenosis under general anesthesia . -
pubmed
One year prior to this admission , the
patient was admitted after a
motor vehicle accident with
subdural hematoma ,
subarachnoid hemorrhage , and
fracture of the eighth thoracic vertebra . -
pubmed
At this admission , the
patient developed acute
left ventricle failure on induction of anesthesia secondary to reverse TCM . -
pubmed
We report a case of reverse
TCM , where posttraumatic emotional stress of a
neuropsychiatric disorder combined with physical stress from anesthesia and laryngoscopy triggered
TCM in a
patient with previous uneventful anesthesia 1 year earlier . -
pubmed
METHODS : We performed a post hoc analysis of data from the Prevention Regimen for Effectively Avoiding Second
Strokes ( PRoFESS ) trial , a randomized clinical trial including 20,332
patients with recent
noncardioembolic ischemic stroke . -
pubmed
CONCLUSIONS : Among
patients with recent
noncardioembolic ischemic stroke , the risk of
ICH is high . -
pubmed
We report real - time cell sensing of two
human cell lines to examine the
cytotoxicity of fourteen
arsenic species :
arsenite (
AsIII ) ,
monomethylarsonous acid (
MMAIII ) originating from the
oxide and
iodide forms ,
dimethylarsinous acid (
DMAIII ) ,
dimethylarsinic glutathione (
DMAGIII ) ,
phenylarsine oxide (
PAOIII ) ,
arsenate (
AsV ) ,
monomethylarsonic acid (
MMAV ) ,
dimethylarsinic acid (
DMAV ) ,
monomethyltrithioarsonate (
MMTTAV ) ,
dimethylmonothioarsinate (
DMMTAV ) ,
dimethyldithioarsinate (
DMDTAV ) ,
3 - nitro-4 - hydroxyphenylarsonic acid (
Roxarsone ,
Rox ) , and
4 - aminobenzenearsenic acid (
p - arsanilic acid ,
p - ASA ) . -
pubmed
METHODS : A retrospective study included all
patients with stage III or IV
HNSCC undergoing curative VMAT . -
pubmed
RESULTS : From 2010 to 2013 , 130
patients were treated for locally advanced oropharynx ( n=55 ; 42 % ) , hypopharynx ( n=38 ; 29 % ) , larynx ( n=22 ; 17 % ) or oral cavity ( n=15 ; 12 % )
SCC . -
pubmed
METHODS : Seven days of activity monitor data were collected for 26 participants with
MS ( age=44.5 + -11.9years ; time since diagnosis=6.5 + -6.2years ;
Patient Determined Disease Steps=<=3 ) . -
pubmed
This commentary points to the need for better understanding of the relationship between
Hg release and
AD in India , and other countries , and how to protect
human health and the environment from the adverse effects of
Hg . -
pubmed
, angle of
strabismus , ocular motility , and acuity ) for 23 consecutive
patients who underwent orbital translocation between 2000 and 2015 and noted the requirement for corrective surgery . -
pubmed
Nontransient change ( favorable or unfavorable ) in angle of
strabismus was noted in 14
patients . -
pubmed
Corrective surgery for
strabismus was performed for four
patients . -
pubmed
The variant
methionine replaces
valine at 66th position is strongly related to
BPD , and an
individual with a homozygous condition of this allele is at a greater risk of developing
MDD . -
pubmed
The length of
SP was measured over 30 mm in 151
patients ( 15.1 % ) . -
pubmed
Here , we aimed to investigate the grey matter and white matter changes in
schizophrenia patients and exhibit the relation of these imaging findings with clinical variables . -
pubmed
METHODS : A total of 20
schizophrenia patients and 16 matched healthy controls underwent magnetic resonance imaging to investigate the grey matter and white matter alterations that occur in
schizophrenia patients using voxel - based morphometry ( VBM ) and whole brain voxel - wise analysis of diffusion tensor imaging ( DTI ) parameters with SPM8 , respectively . -
pubmed
RESULTS : Bilateral insula showed decreased grey matter volume in
schizophrenia patients compared with healthy controls ( P & lt ; 0.01 ) . -
pubmed
Psychiatric scores , duration of illness , and age were not correlated with the decreased grey matter volume of insula in
schizophrenia patients . -
pubmed
METHODS AND RESULTS : Between 2013 and 2016 , a total of 18
patients with
PVT was treated with a 40 mg bolus dose of
tenecteplase . -
pubmed
Thrombolysis was followed by
enoxaparin and oral anticoagulation in
patients , all of whom had complete lysis of
thrombus and clinical improvement . -
pubmed
Our previous report indicated that
vascular injury enhances vascular remodeling in fetal growth restriction ( FGR )
mice . -
pubmed
PATIENTS AND METHOD : A descriptive cross - sectional study of 428
patients over the age of 65 admitted for
trochanteric or cervical fractures in 2015 , in which gender , age , previous diagnosis , external causes associated with
fracture and place of the event were recorded . -
pubmed
RESULTS : There were 220
patients with a
cervical fracture ( 51.4 % ) and 208 patients with a
trochanteric fracture ( 48.6 % ) . -
pubmed
Effects of Antiepileptic Drugs on Spontaneous Recurrent
Seizures in a Novel Model of Extended Hippocampal Kindling in
Mice . -
pubmed
Subsequently ,
animals underwent continuous video / EEG monitoring for
seizure detection . -
pubmed
Spontaneous recurrent
seizures were consistently observed in extended kindled
mice but no
seizures were detected in the control
animals . -
pubmed
No gross
brain lesions were observed in a set of extended hippocampal kindled
mice submitted to histological evaluation . -
pubmed
Circulating Endothelial Progenitor Cells Present an Inflammatory Phenotype and Function in
Patients With
Alcoholic Liver Cirrhosis . -
pubmed
A comprehensive characterization of circulating EPCs using more than 30 phenotype markers was performed by mass cytometer time of flight ( CyTOF ) in an independent cohort of age and gender matched
ALC patients ( n = 4 ) and controls ( n = 5 ) . -
pubmed
CD45int and CD45hi EPCs significantly increased in
ALC patients compared to controls ( p - val = 0.006 ) . -
pubmed
Conclusions : We report the first extensive characterization of circulating
human EPCs with distinct
EPC subtypes . -
pubmed
The present study identified that microRNA ( miR-28 - 5p ) was involved in the migration and invasion of
gastric cancer cells , and was able to affect the prognosis of
patients with
gastric cancer . -
pubmed
As more and more therapeutic options are now available , we will delineate a potential therapeutic algorithm for the optimization of daily life treatment choice of
NSCLC patients . -
pubmed
The present study was chosen
Hibiscus rosa - sinensis flowers to analyze its antimicrobial capabilities against
venereal diseases causing pathogens . -
pubmed
After that , the different concentrations of
1,2 benzene dicarboxylic acid were tested on
human diseases causing microbial
strains . -
pubmed
Selective
serotonin reuptake inhibitor use and mortality ,
postoperative complications , and quality of care in
hip fracture patients : a Danish nationwide cohort study . -
pubmed
Conclusion : In
patients undergoing
hip fracture surgery , 30 - day mortality and overall readmission risk were elevated in both current and former SSRI users compared with non - users . -
pubmed
Gastric Electrical Stimulation Improves Symptoms of
Diabetic Gastroparesis in
Patients on Peritoneal Dialysis-2 Case Reports . -
pubmed
The exact prevalence of
patients with severe
DGP and
ESRD is not known ; however , finding a therapeutic approach to these patients , particularly those whose
gastroparesis symptoms preclude them from undergoing kidney transplant procedure , represents a huge challenge . -
pubmed
Our experience suggests that GES implantation can be an effective treatment modality for
type 1 diabetic patients on peritoneal dialysis ( PD ) who are simultaneous pancreas - kidney transplantation candidates , by improving the severity and frequency of
gastroparesis symptoms and eventually ensuring their optimal nutritional and fluid intake . -
pubmed
The herbal medicine combination of notoginseng -
safflower has been commonly used clinically for the prevention and treatment of
cardiovascular diseases . -
pubmed
METHODS :
Patients with
migraine aura were interviewed in order to obtain characteristics of
migraine aura . -
pubmed
MATERIAL AND METHODS : From September 2010 to October 2017 , radical prostatectomy was done for 123 sequential
patients with
localized prostate cancer in two referral centers of Shahid Beheshti Medical University , Tehran , Iran , and 42 cases with Gleason Scores 3 + 3 which who were candidates for active surveillance were included in the study . -
pubmed
RESULTS : Thirty of 42 ( 71.4 % )
patients had significant
tumor volumes ( & gt;=0/5 cm3 ) . -
pubmed
When
tumor volume was less than 0.5 cm3 , none of the
patients had extra
prostatic tumor extension . -
pubmed
In
patients with
tumor volume greater than 0.5 cm3 , two cases ( 6.6 % ) had extra prostatic extension , 4 cases ( 13.3 % ) had positive margins , four cases ( 13.3 % ) reactive lymph nodes and 16 cases ( 53.3 % ) perineural invasion . -
pubmed
CONCLUSION : We suggest that some
patients with Gleason Score 3 + 3 have
tumor volume & gt;0.5 cm3 who are considered having significant
cancer pathology and active surveillance may not be appropriate approach to manage all cases with Gleason Score 3 + 3 . -
pubmed
METHODS : We performed a retrospective review of
TBI patients who underwent cruciate DC . -
pubmed
Long - term rhythm monitoring with an implantable loop recorder in
patients after the first clinical
atrial fibrillation episode . -
pubmed
In this work , we found that lncRNA CASC11 was significantly up - regulated in the
glioma specimens and cells , and the ectopic overexpression indicated the poor prognosis of
glioma patients . -
pubmed
Pulmonary embolism during the third cycle of alemtuzumab in a
patient with
relapsing multiple sclerosis . -
pubmed
This paper reports a case of young
patient who developed
pulmonary embolism during the third cycle of
alemtuzumab . -
pubmed
Nevertheless ,
postoperative pain remains a major challenge in
patient care . -
pubmed
The mid - term survival rate for the Oxford UKA in patients with morbid
obesity is similar to that of other nondesigner
patient series with
BMI & gt;= 30 , which provides further evidence for the safety of the implant in this
patient population with significant improvements on PROMs at short and mid - term follow - up . -
pubmed
Objective :
Aloperine (
ALO ) , an alkaloid isolated from the leaves of
Sophora alopecuroides , has been suggested to exhibit anti - inflammatory and anti -
tumor properties and is traditionally used to treat various
human diseases , including
cancer . -
pubmed
This study investigated the clinical symptom profile and its associations with the results of quantitative sensory testing ( QST ) and the quantitative sudomotor axon reflex test ( QSART ) as well as the quality of life ( QOL ) in
patients with clinically suspected
SFN . -
pubmed
METHODS : This study involved 63
patients with clinically suspected length - dependent
SFN . -
pubmed
, mucosal
ulceration or granulation tissue in the larynx ) was present in 57
patients ( 57 % ) . -
pubmed
Patients with
laryngeal injury had significantly worse
patient - reported breathing ( Clinical
Chronic Obstructive Pulmonary Disease Questionnaire : median , 1.05 ; interquartile range , 0.48 - 2.10 ) and
vocal symptoms ( Voice Handicap Index-10 : median , 2 ; interquartile range , 0 - 6 ) compared with patients without
injury ( Clinical
Chronic Obstructive Pulmonary Disease Questionnaire : median , 0.20 ; interquartile range , 0 - 0.80 ; p & lt ; 0.001 ; and Voice Handicap Index-10 : median , 0 ; interquartile range , 0 - 1 ; p = 0.005 ) . -
pubmed
CONCLUSIONS : Acute
laryngeal injury occurs in more than half of
patients who receive mechanical ventilation and is associated with significantly worse breathing and voicing 10 weeks after extubation . -
pubmed
Human colon carcinoma cells (
HCT 116 ) were chosen to elucidate whether
DEHP triggers oxidative stress and apoptosis . -
pubmed
Risk of pregnancy - related
venous thromboembolism and obstetrical complications in
women with
inherited type I antithrombin deficiency : a retrospective , single - centre , cohort study . -
pubmed
METHODS : We made a retrospective analysis of four pediatric
patients diagnosed with
DAH and
pulmonary microangiopathy due to
cblC deficiency between January 2017 and December 2018 in Beijing Children 's Hospital . -
pubmed
RESULTS : This study describes four
patients with their ages ranging from 4 years 2 months to 7 years 6 months with
cblC deficiency who developed late - onset
diffuse lung disease (
DLD ) . -
pubmed
Of these , the first three
patients presented predominantly with
DAH , and the last
patient with
pulmonary microangiopathy confirmed by thoracoscopic lung biopsy . -
pubmed
All
patients were accompanied by
pulmonary arterial hypertension (
PAH ) , two accompanied by
respiratory failure , and two accompanied by moderate
megaloblastic anemia . -
pubmed
All
patients were suspected of having
idiopathic pulmonary hemosiderosis or
interstitial lung disease at other hospitals . -
pubmed
The samples consisted of 60 tissue specimens from
patients with
squamous cell carcinoma ,
epithelial dysplasia and controls ( n=20 / group ) . -
pubmed
It is established that the products of protein metabolism ,
pigment , Weibel - Palade body and various sizes of
blood clots accumulate in the cavity subaroundal cone of heart in old
rats . -
pubmed
Thyroid gland changes in
patients with
acromegaly . -
pubmed
The aim of the present study was to find the prevalence of
thyroid dysfunction and
goiter in
patients with
acromegaly and determine its relationship to disease activity , disease duration , and the presence of
secondary hypothyroidism . -
pubmed
SUBJECTS AND METHODS : In a cross - sectional study of the period 2008 - 2012 were included 146
patients with
acromegaly ( 56
men , 90
women ) of mean age 50.3 + - 12.4 years . -
pubmed
Acromegaly disease activity and thyroid function were evaluated in all
patients . -
pubmed
Goiter was diagnosed in 87 % of
patients , including diffuse
goiter ( 17.1 % ) and nodular ( 69.9 % ) , with no significant difference between patients with active and controlled disease or the presence of
secondary hypothyroidism . -
pubmed
CONCLUSIONS : Thyroid volume in
patients with
acromegaly depends on disease activity and the presence of
secondary hypothyroidism as a complication . -
pubmed
The increased prevalence of
nodular goiter determines the need of regular ultrasound thyroid evaluation in the follow - up of
patients with
acromegaly . -
pubmed
L can enter the
human organism during the treatment of
helminthiasis as well as during the using the contaminated
cocaine . -
pubmed
Cancer - related
death was particularly increased in
patients with low RTE levels ( 4.23 ; 95%CI , 1.43 - 12.13 ; p = 0.007 ) . -
pubmed
Studies reported that
tobacco addiction was related to
visual impairments , but one unresolved issue is whether the impairments are related to the many compounds existing in the cigarettes or to the effects of
nicotine . -
pubmed
Inter - reader agreement of high - resolution computed tomography findings in
patients with COVID-19
pneumonia : A multi - reader study . -
pubmed
METHOD : Seventy - seven consecutive
patients ( mean age , 64 + - 15 years ) with mild COVID-19
pneumonia that underwent HRCT were retrospectively included . -
pubmed
This study evaluated the effects of probiotic and
selenium co - supplementation on clinical and metabolic symptoms in
patients with
chronic schizophrenia . -
pubmed
A randomized , double - blind , placebo - controlled trial was conducted among 60
people with
chronic schizophrenia to receive either 8 x 109 CFU / day probiotic plus 200 mug / day
selenium ( n = 30 ) or placebo ( n = 30 ) for 12 weeks . -
pubmed
Probiotic and
selenium co - supplementation for 12 weeks to
patients with
chronic schizophrenia had beneficial effects on the general PANSS score and some metabolic profiles . -
pubmed
Human PRV Infection in China : An Alarm to Accelerate Eradication of PRV in Domestic Pigs . -
pubmed
A value of r = 0,86 and 0,85 was found for both fixed and variable area radionuclide methods when these ejection fraction values were correlated with cardio - angiographic ejection fraction values in normal subjects and in
patients with
myocardial infarction . -
pubmed
[ Studies on correlation between alterations in serum
sialic acid levels and remission ,
metastasis , and
recurrence of diseases in
patients with
cancer ( author 's transl ) ] . -
pubmed
Positive results obtained in the three methods were particularly found in
patients with diseases generally presumed to represent
immune complexes diseases including
acute glomerulonephritis ,
systemic lupus erythematosus ,
polyarteritis nodosa , subacute
bacterial endocarditis , and
acute or chronic hepatitis . -
pubmed
We observed idiopathic light - chain
proteinuria in a
patient with
multiple abnormalities of proximal - tubule transport mechanisms (
Fanconi syndrome ) ,
nephrogenic diabetes insipidus , and
distal renal tubular acidosis . -
pubmed
A 29 year old
woman is described with severe
hyperemesis gravidarum ,
atypical migraine , numerous admissions to hospital for
psychiatric illness ,
non - epileptic seizures , and
valproate - induced
coma . -
pubmed
Thirty - four
patients who had resection of
cancer of the pancreatic head were examined clinicopathologically to elucidate neural invasion of
cancer of the pancreatic head to the extrapancreatic nerve plexus . -
pubmed
Invasion of
cancer to the retropancreatic tissue ( rp+ ) was observed in 29 ( 85 % ) of the 34
patients , and neural invasion to the extrapancreatic nerve plexus was observed in 21 ( 72 % ) of the 29
patients with rp+ . -
pubmed
Complex study of cellular and humoral defense reactions in
patients with
acute cholecystitis revealed a decrease in their level , decelerated change of the neutrophil phase to the mononuclear phase , and increased metabolic phagocyte activity in the focus of affection . -
pubmed
[
Epilepsy detected in
diabetes in
patients over 50 years ] . -
pubmed
Epilepsy over the age of 50 years represents 14 % of the
persons hospitalized in this age group , and 32 % of all
epileptics hospitalized at Dakar U. H. C. The etiologies of these
epilepsies reveal 8.30 %
metabolic encephalopathics , and 3.35 % diabetics . -
pubmed
The effects of glucocorticoids on the availability of
L - tryptophan and
tyrosine in the plasma of
depressed patients . -
pubmed
In order to investigate the effect of glucocorticoid excess on the availability of
L - TRP and
tyrosine to the brain , we measured urinary
cortisol ( UC ) excretion in 24 - h urine , and the availability of both
amino acids before and after treatment with 1 mg
dexamethasone in 26
depressed patients . -
pubmed
Major
depressed patients with
melancholia exhibited a significantly lower availability of
L - TRP than minor
depressives ( P = 0.007 ) . -
pubmed
[ Role of drug assays in the treatment of
epileptic patients ] . -
pubmed
Indications for pelvic lymph node dissection in
patients with clinically confined
carcinoma of the prostate . -
pubmed
The combination of
haloperidol , 5 mg , and
lorazepam , 4 mg , was both effective and safe for managing
agitated behavior in an open trial with acutely
psychotic patients . -
pubmed
Ongoing electrical activity of superior cervical
ganglion cells in
mammals of different size . -
pubmed
The ongoing synaptic activity of superior cervical
ganglion cells in adult
mammals was examined in situ by intracellular recording in anesthetized
mice ,
hamsters ,
rats ,
guinea pigs , and
rabbits . -
pubmed
Viraemia with
human parvovirus . -
pubmed
Cyclosporine therapy in chronic slowly progressive
polymyositis -- preliminary report of clinical results in three
patients . -
pubmed
[ Studies on anti -
arrhythmia effects of
panaxatriol saponins isolated from
Panax notoginseng ] . -
pubmed
Using a logistic discriminant function we retrospectively evaluated the diagnostic value of laboratory features and abdominal sonography in 70
patients with
jaundice . -
pubmed
18
patients had an extrahepatic obstruction of the common bile duct ( EHO ) , 22
patients had
metastatic liver disease (
MLD ) and 30
patients had an infectious or
toxic hepatocellular disease (
HCD ) . -
pubmed
An undoubtedly dilated common bile duct was seen in 56 % of the
patients with
EHO and in none of the other patients . -
pubmed
Metastatic lesions were seen exclusively in 81 % of the
patients with
MLD . -
pubmed
No distinct sonographic sign could be found for the
patients with
HCD . -
pubmed
Biosynthesis of leukotoxin ,
9,10 - epoxy-12 octadecenoate , by leukocytes in lung lavages of
rat after exposure to
hyperoxia . -
pubmed
Age was significantly correlated ( P less than 0.0002 ) with lateral ventricular size , but the institutionalized
schizophrenic patients had significantly larger ( P less than 0.025 ) lateral ventricles than the neurotics when age was taken into account . -
pubmed
Within the group of institutionalized
schizophrenic patients few correlates of
ventricular enlargement were identified ; thus in this population increased ventricular size was not clearly associated with the features of the defect state ( negative symptoms and
intellectual impairment ) . -
pubmed
[ Study of a transplantable
epidermoid epithelioma of the skin of the C3H
mouse ] . -
pubmed
Hypnosis in the treatment of a
child 's
allergy to
dogs . -
pubmed
Rabies today --
man and animals . -
pubmed
Studies on homotransplantable
lymphomas in
hamsters . -
pubmed
[ Biological effects of the combined action of laser radiation and
methylene blue on a
strain of
Salmonella typhimurium ( TA 1538 ) ( I ) ] . -
pubmed
A new set of trials they are making on
Salmonella typhimurium TA 100 strain with plasmid pK M 101 that give to strain greatest susceptibility for mutagenetic agents . -
pubmed
Lymphocyte
cytotoxicity in the peritoneal cavity and blood of
patients with
ovarian cancer . -
pubmed
After an intensive course of combination chemotherapy , 16
patients with minimal residual
ovarian cancer that was documented at second - look laparotomy , had an indwelling Tenckhoff catheter placed and underwent multiple peritoneal saline lavages . -
pubmed
Peritoneal natural killer lymphocyte cytotoxicity and antibody - dependent cell - mediated
cytotoxicity were very low in all but two
patients . -
pubmed
These results suggest that lymphocytes collected from the peritoneal cavity of
patients with minimal residual
ovarian cancer are deficient in natural and antibody - dependent cytotoxic effector function . -
pubmed
A phase II study of the combination ,
1,3 - bis ( 2 - chloroethyl )- 1 - nitrosourea (
BCNU ) and
N -( phosphonacetyl )- L - aspartate (
PALA ) , in
patients with advanced large
bowel cancer . -
pubmed
Thirty
patients with advanced metastatic
colorectal carcinoma were treated with the combination
BCNU ( 200 mg / m2 ) every 6 weeks , and
PALA ( 5.0 g / m2 ) every 3 weeks . -
pubmed
Control of susceptibility of
F344 rats to adjuvant
arthritis : an alternative interpretation . -
pubmed
Diastolic murmur (
DM ) in
patients with
non - obstructive hypertrophic cardiomyopathy (
non - obst HCM ) was studied regarding incidence , phonocardiographic disposition , mechanism , and also clinical characteristics of
patients with
DM . -
pubmed
The results were as follows : 1 )
DM was recorded in 17 of 115
patients with non - obst
HCM ( 15 % ) , and was classified into three types of a
mid - diastolic murmur , presystolic murmur ,
presystolic murmur and these combination . -
pubmed
Therefore , auscultatory or phonocardiographic assessment of
DM was clinically useful in the evaluation of
patients with non - obst
HCM . -
pubmed
In the past five years , the use of chemotherapy has also assumed a major role in treating
micrometastases in
breast cancer in selected premenopausal and postmenopausal
patients . -
pubmed
Similar nuclear changes have until now only been reported in
man in relation to
tumors or other pathological conditions . -
pubmed
We studied two
patients who manifested many of the varied clinical signs of
Vogt - Koyanagi - Harada syndrome , but who also showed focal neurologic involvement , including
acute transverse myelitis and
ciliary ganglionitis . -
pubmed
Preliminary inhalation of
oxygen in conscious
rabbits prevents increased respiratory muscle activity caused by
airway occlusion . -
pubmed
Chronically ill institutionalized
children : psychosocial effects of prolonged hospitalization of the terminally sick child . -
pubmed
Electropalatographic and perceptual analysis of the speech of Cantonese
children with
cleft palate . -
pubmed
This study used electropalatographic and perceptual analysis to investigate the speech of two Cantonese
children with repaired
cleft palate . -
pubmed
beta blockers have been shown to decrease subsequent cardiovascular events in
patients with
acute myocardial infarction ; however , adverse effects are often associated with their use . -
pubmed
In
patients with
coronary artery disease and symptoms resulting from either fixed obstruction or
vasospasm , these agents decrease the frequency of
angina episodes . -
pubmed
Calcium antagonists appear to be well tolerated in
patients with concomitant conditions such as
diabetes and are effective in commonly coexistent
cardiovascular disorders such as
hypertension . -
pubmed
MATERIALS AND METHODS : Thirty - one
patients with autonomous
thyroid nodules underwent a cycle of treatment with percutaneous injection of
ethanol in multiple sessions ( three to seven ) on alternate days depending on the diffusion of the
ethanol in the nodule . -
pubmed
Symptoms resolved in 73 % of the
hyperthyroid subjects after the first cycle of treatment and in 93 % of these
subjects after the second . -
pubmed
Diarrheal illness without concomitant respiratory symptoms was monitored among 221
children aged & lt ; 3 years in 37 classrooms ( 24 day - care centers ) through biweekly parental telephone interviews from October 1988 to May 1989 in Cumberland County , North Carolina . -
pubmed
Helicobacter pylori is probably the most common
bacterial infection worldwide and the accepted cause of
chronic active gastritis . -
pubmed
What is true for duodenal
ulcers is also true for patients with
gastric ulcer who are infected with
H. - pubmed
The risk of recurrent
ulcer complications with
bleeding is virtually abolished following successful eradication of
H. - pubmed
At this time it is reasonable to consider all patients with confirmed
duodenal or gastric ulcer for eradication of
H. - pubmed
An abattoir - based study of the prevalence of subclinical
Johne ' s disease in adult
cattle in south west England . -
pubmed
The prevalance of subclinical
Johne ' s disease was estimated in adult
cattle slaughtered at three major abattoirs in south west England . -
pubmed
OBJECTIVE : The decision to perform total hip arthroplasty ( THA ) in
patients with
osteoarthritis (
OA ) of the hip is based largely on patients ' reports of
pain and disability and not on radiographic findings of
OA . -
pubmed
METHODS : Individual radiographic features (
osteophytes , joint space narrowing ,
sclerosis ,
cysts ,
deformity ) and global severity of
hip OA were assessed in 95 consecutive elderly
patients with
hip OA undergoing THA who were enrolled in a Patient Outcome Research Team ( PORT ) project . -
pubmed
RESULTS : Eighty - seven
patients ( 91.5 % ) had either severe or moderate
OA in the hip to be replaced ; 17 % of these had a previous contralateral THA . -
pubmed
Eight
patients with either primary or secondary
osteoarthritis of the hip received uncemented total hip prostheses . -
pubmed
Patients with
epilepsy develop
psychosis or
schizophrenia at a rate exceeding that expected if the two disorders were independent . -
pubmed
Neuropathological investigations into the anatomic substrate of
seizures in
patients with
psychosis or
schizophrenia are consistent with the notion that there are
neurodevelopmental abnormalities involving the mesial temporal lobe . -
pubmed
Finally , clinical recommendations for the evaluation and pharmacological management of
patients with
schizophrenia who have one or more
seizures are described . -
pubmed
PURPOSE : To report treatment of a
patient with acute
retinal necrosis during pregnancy . -
pubmed
METHODS : A 24 - year - old
woman in her twenty - third week of gestation was diagnosed with acute
retinal necrosis . -
pubmed
The
pancreatic lesion masses were found in all the
non - AIDS patients and in one patient with
AIDS and were located in the head of the pancreas in two cases and involved the body , neck , and head of the gland in the other two . -
pubmed
In
patients with
right ventricular failure , a decrease in afterload was attained by a cavo - bipulmonary anastomosis associated with the intraventricular repair . -
pubmed
The authors conclude that high risk
patients with
Ebstein ' s anomaly have a lower operative mortality and improved functional tolerance when there is persistent
tricuspid regurgitation after cavo - bipulmonary anastomosis . -
pubmed
Epileptic seizures are a principal
brain dysfunction with important public health implications , as they affect 0.8 % of
humans . -
pubmed
Our objective was to follow the transition into
seizure by reconstructing intracranial recordings in implanted
patients as trajectories in a phase space and then introduce non - linear indicators to characterize them . -
pubmed
Recommendations for the treatment of
lipid disorders in
patients on peritoneal dialysis . -
pubmed
It seeks to determine the annual transition probabilities from
chronic hepatitis to
cirrhosis and the
HCV incidence per year in the past . -
pubmed
These unknowns are found by fitting the observed
deaths from
HCC that are attributable to
HCV . -
pubmed
Optimal values for these unknowns then allow to project the number of
HCC deaths attributable to
HCV for each year through 2025 ( for patients infected before 1996 ) . -
pubmed
It predicts that
HCC mortality related to
HCV will continue to increase through 2020 in the absence of treatment , with a 150 % increase in the yearly incidence among men and 200 % among women . -
pubmed
The metabolism of
glucose and
cellobiose , products of cellulose hydrolysis , was investigated in four cellulolytic
strains of the genus Fibrobacter :
Fibrobacter succinogenes S85 , 095 , HM2 and
Fibrobacter intestinalis NR9 . -
pubmed
Can coronary blood flow velocity pattern after primary percutaneous transluminal coronary angioplasty [ correction of angiography ] predict recovery of regional left ventricular function in
patients with
acute myocardial infarction ? -
pubmed
This study sought to investigate parameters derived from the coronary blood flow velocity spectrum immediately after primary PTCA in
patients with
acute myocardial infarction and to elucidate the clinical value of coronary blood flow measurement in predicting myocardial viability . -
pubmed
METHODS AND RESULTS : Using a Doppler guidewire , we measured coronary blood flow velocity after successful completion of primary PTCA in 23 consecutive
patients with acute
anterior myocardial infarction . -
pubmed
When 9
patients with a daily intake of SPC and a
citrate excretion below 2.5 mmol / day were compared with 16
hypocitraturic patients only given drinking advice , the cumulated percentages of
patients without recurrent
stone formation in the 2 groups after 3 years were 44 % and 48 % , respectively . -
pubmed
The rate of
stone formation was apparently slightly reduced , but the fraction of
patients free of
recurrence was no different from that in patients without medical treatment . -
pubmed
RESULTS : A total of 116
patients with confirmed
GBC were admitted during these five years . -
pubmed
We analyzed the results of a three or more drug combination as treatment for moderate or severe
cGVHD developing after transplantation for
thalassemia , in 45
patients with median age of 11 ( range 2 - 26 ) years . -
pubmed
This retrospective study showed that a three or more drug combination is safe and effective for treatment of moderate or severe
cGVHD at least in younger
patients . -
pubmed
78.26 % patients with
peptic ulcer associated with
H. - pubmed
pylori ( Toxin+ ) , while 42.86 % patients with
gastritis was infected with
H. - pubmed
There was a closed relationship between
infection with
H. - pubmed
Bilateral
human fetal striatal transplantation in
Huntington ' s disease . -
pubmed
BACKGROUND : Transplanted striatal cells have been demonstrated to survive , grow , establish afferent and efferent connections , and improve behavioral signs in
animal models of
Huntington ' s disease (
HD ) . -
pubmed
OBJECTIVE : To evaluate feasibility and safety and to provide preliminary information regarding the efficacy of bilateral
human fetal striatal transplantation in
HD . -
pubmed
METHODS : Seven symptomatic
patients with genetically confirmed
HD underwent bilateral stereotactic transplantation of two to eight fetal striata per side in two staged procedures . -
pubmed
RESULTS : Three
subjects developed
subdural hemorrhages (
SDHs ) and two required surgical drainage . -
pubmed
One
subject died 18 months after surgery from probable
cardiac arrhythmia secondary to severe
atherosclerotic cardiac disease . -
pubmed
Patients with moderately advanced
HD are at risk for
SDH after transplantation surgery . -
pubmed
Human infection with Nocardia species presents as a wide range of clinical
syndromes . -
pubmed
We report a case of primary
Nocardia asteroides osteomyelitis as the initial clinical presentation of
AIDS . -
pubmed
The most common species isolated from cases of
pityriasis versicolor was
M. - pubmed
In both adult and suckling infant cases of
seborrhoeic dermatitis ,
M. - pubmed
In addition , scales were collected from lesions of
pityriasis versicolor for use as the template , and the involved Malassezia species were identified by the PCR method using the DNA sequences of nuclear ribosomal internal transcribed spacer l. The most commonly detected species was
M. - pubmed
The expression of
human blood type
antigens in
Neijiang pigs was different from other
pig strains reported , it was suggested that it was possible to find a
pig strain that contained less
xenoantigen . -
pubmed
These acute effects demonstrate the possibility of functional and metabolic amelioration by TMLR after
ischemia induced by microembolization in an isolated hemoperfused
pig heart . -
pubmed
The brain matrix and multifocal
brain damage following a single injection of
ketamine in young adult
rats : conspicuous changes in old age . -
pubmed
The
rats which had received the
ketamine after the
seizures were significantly heavier than either the normal
rats or the other group of seized
rats . -
pubmed
Compared to the
acepromazine - treated
rats , the
ketamine - treated
rats did not exhibit spontaneous
seizures and exhibited cerebral widths comparable to normal
rats . -
pubmed
EXPERIMENTAL DESIGN : We performed gene expression analysis on
mesothelioma tissue specimens from 16
patients and compared these to 4 control pleural tissue samples using cDNA microarray filters with 4132 clones . -
pubmed
Excess
weight gain is a major cause of increased blood pressure in most
patients with essential
hypertension , and also greatly increases the risk for
renal disease . -
pubmed
Special considerations for the
obese patient , in addition to adequately controlling the blood pressure , include correction of the
metabolic abnormalities and protection of the kidneys from further
injury . -
pubmed
Electroencephalographic findings in
children , previously treated for
asphyxia neonatorum . -
pubmed
There were 119
patients ( 44 female and 75 male ): 73
patients had simple d -
TGA , 36 had d - TGA with
ventricular septal defect , and 10 had a Taussig - Bing heart . -
pubmed
At latest follow - up , there was no or trivial
AR in 88
patients , mild
AR in 29
patients , and moderate to severe
AR in 3
patients . -
pubmed
Only 3
patients required surgical intervention for
AR . -
pubmed
[ Biological support of
Echinococcus granulosus and epidemiology of
hydatidosis ] . -
pubmed
[
Streptomycin therapy of
human tuberculosis and associated diseases ] . -
pubmed
Patient with
diabetes mellitus is prone to develop the
vascular lesion of blood vessels of all kinds . -
pubmed
Also with this study blood brain barrier change in the
diabetes mellitus patients was observed . -
pubmed
In
patients with
diabetes mellitus the level of
glucose and
total proteins increased in the cerebrospinal fluid . -
pubmed
Blood brain barrier permeability changes in the
patients with
ICV as well as in the
patients without
ICV correlate with the values of
diabetes mellitus in blood . -
pubmed
While the wild - type
strain effectively kills the nematode
Caenorhabditis elegans , the pathogenicity of mutants with defective quorum sensing is attenuated . -
pubmed
cenocepacia but also by many other
strains of the
Burkholderia cepacia complex . -
pubmed
How is pulmonary arterial blood flow affected by
pulmonary venous obstruction in
children ? -
pubmed
MATERIALS AND METHODS : Twelve
children ( age range 3 - 180 months ) who had undergone MRI for
pulmonary vein stenosis were identified . -
pubmed
Nine of the
patients had unilateral
stenosis ; three had bilateral involvement . -
pubmed
RESULTS : Unilateral
vein stenosis was associated with diastolic reversal in the ipsilateral branch pulmonary artery ( mean flow reversal 12.3 % , range 2.4 - 42 % ) and continuous diastolic forward flow in the contralateral pulmonary artery in seven of nine
patients . -
pubmed
All
patients sustaining acute
biliary pancreatitis were enrolled . -
pubmed
Patients with clinical
jaundice and severe
pancreatitis were excluded . -
pubmed
All
patients underwent intra - operative cholangiography ( IOC ) or pre - operative endoscopic retrograde cholangiography ( ERCP ) , which was indicated based on the odds of
choledocholithiasis . -
pubmed
CONCLUSION : The best predictor of
choledocholithiasis in
patients sustaining mild acute
pancreatitis was the
biliary tract dilatation in pre - operative US . -
pubmed
Preliminary examination of
VaD subtypes revealed
patients with
subcortical infarct or
SH - only exhibited greater decline than
VaD patients with
cortical lesions . -
pubmed
Yet ,
RA preferentially affects elderly
individuals , in whom adaptive immunity to exogenous antigens begins to fail . -
pubmed
Complete response was observed in 3 ( 7.9 % )
patients , partial response in 20 ( 52.6 % ) ( overall response rate 60.5 % ) , stable disease in 11 ( 28.9 % ) and
disease progression in 4 ( 10.5 % ) . -
pubmed
Rates of decline in soil were similar in the laboratory at 20 degrees C for two
strains of
L. - pubmed
METHODS : Dextran
sodium sulfate - induced
colitis and
Salmonella typhimurium - induced
enterocolitis were used as animal models to study
colitis . -
pubmed
The case reported herein describes a 12 - year - old
boy affected by
cranio - facial dysmorphism and
monolateral conductive hearing loss in the right ear : followed from radiological diagnosis -- carried out to study a
malformation of the ear pinna -- to surgical treatment . -
pubmed
We describe the first case of
Pisa syndrome during
aripiprazole treatment in an elderly ( 77 - year - old )
woman , admitted to hospital for behavioural and psychological symptoms of
dementia . -
pubmed
In vivo ,
PXD101 displayed single - agent antitumor activity on
human A2780 ovarian cancer s.c . -
pubmed
METHODS : The patients were healthy premenopausal
women with
HSDD , aged 22 - 50 years . -
pubmed
CONCLUSION : The result of this study suggests that
COCs in premenopausal
women with
HSDD are associated with lower
androgen levels than those not on
COCs . -
pubmed
Our results demonstrate that in contrast to
laxaphycin A ,
laxaphycin B inhibits the proliferation of sensitive and resistant
human cancer cell lines and that this activity is strongly increased in the presence of
laxaphycin A. -
pubmed
Carbon dioxide (
CO ( 2 ) ) is required for growth of
Actinobacillus actinomycetemcomitans ( Aa ) , the reputed cause of
LAgP. -
pubmed
Bicarbonate , a source of
CO ( 2 ) , buffers acid production by
Streptococcus mutans (
Sm ) , a key organism associated with
caries . -
pubmed
The purpose of this study was to determine whether the saliva of
LAgP patients and subjects with Aa had higher levels of
bicarbonate , or an elevated pH , and/or reduced survival of Sm . -
pubmed
Patient- and
death - censored graft survival at 12 months were 86 % and 88 % , respectively . -
pubmed
Bacterial ( 0.66 + /- 1.0 vs 1.48 + /- 1.26
infections per patient per year , P = .009 ) and
viral infections ( 0.9 + /- 0.71 vs 1.41 + /- 0.71 ; P = .006 ) were more frequent in the higher dose group . -
pubmed
aeruginosa , the peptide highly protected
mice against death by
sepsis . -
pubmed
Hearing impairment is the most common
sensorineural disorder in
humans . -
pubmed
Incretin levels and effect are markedly enhanced 1 month after Roux - en - Y gastric bypass surgery in obese
patients with
type 2 diabetes . -
pubmed
Tuning major gene variants conditioning
human behavior : the anachronism of
ADHD . -
pubmed
The median survival of brain
metastasis patients with
breast cancer of 19 months appears favorable compared with the general brain
metastasis population . -
pubmed
[ Validation of MRI and
18F - FDG - PET coregistration in
patients with primary
brain tumors ] . -
pubmed
OBJECTIVE : To evaluate the role of PET and MRI fused image study
inpatients with primary
brain tumors previously treated , to determine the presence of
radionecrosis vs residual
tumor viability . -
pubmed
RESULTS : Fifty - seven
patients were studied , 37 had
high grade gliomas ; 9 had
oligoastrocytomas ; 5 had
Embrionary tumors ; I had a
meningyoma and I had an oliodendroglial
tumor . -
pubmed
Gene expression of cold
shock and other stress - related genes in
Vibrio vulnificus grown in pure culture under shellstock temperature control conditions . -
pubmed
Shellstock refrigeration after harvesting is recommended to prevent further increases in
Vibrio vulnificus numbers in oysters , but it could potentially induce a cold
shock response in this bacterium . -
pubmed
139
patients with
achalasia of cardiac orifice among which two third were women and one third -- men aged 20 - 65 years have been observed . -
pubmed
Renal sparing surgery for
children with bilateral
Wilms tumor . -
pubmed
BACKGROUND / AIMS : In
patients with
hepatocellular carcinoma (
HCC ) exceeding the Milan criteria , the
recurrence rate after liver transplantation is over 50 % . -
pubmed
We investigated pretransplant factor(s ) that could predict recurrence after living donor liver transplantation ( LDLT ) in
patients with
HCC exceeding the Milan criteria . -
pubmed
METHODS : Pre - operative imaging showed that , of the 111
HCC patients who underwent LDLT between June 1995 and January 2006 , 37 exceeded the Milan criteria . -
pubmed
The 2 - year
HCC recurrence rates in
patients with 0 , 1 , 2 and 3 factors were 0 % ( 0/4 ) , 9 % ( 1/16 ) , 80 % ( 8/10 ) and 100 % ( 7/7 ) respectively ( P<0.001 ) . -
pubmed
CONCLUSIONS : In
patients with
HCC exceeding the Milan criteria , the three pretransplant factors that may be useful for identifying those with high
HCC recurrence potential after LDLT are
tumour size & gt;6 cm , progressive disease after pretransplant treatment and
tumour exposed to the liver surface . -
pubmed
BACKGROUND :
Efavirenz is used for the antiretroviral treatment of
HIV /
tuberculosis - coinfected patients in developing countries . -
pubmed
Phase 3 trials in
patients with advanced , metastatic ,
hormone refractory prostate cancer are under way . -
pubmed
Ciguatera fish poisoning : treatment , prevention and management . -
pubmed
INTRODUCTION : Case studies indicate that
cardiac sarcoid may mimic the clinical presentation of
arrhythmogenic right ventricular dysplasia /
cardiomyopathy (
ARVD / C ) ; however , the incidence and clinical predictors to diagnose
cardiac sarcoid in
patients who meet International Task Force criteria for
ARVD / C are unknown . -
pubmed
METHODS AND RESULTS :
Patients referred for evaluation of
left bundle branch block ( LBBB)-type
ventricular arrhythmia and suspected
ARVD / C were prospectively evaluated by a standardized protocol including right ventricle ( RV ) cineangiography - guided myocardial biopsy . -
pubmed
Sixteen
patients had definite
ARVD / C and four had probable
ARVD / C. Three
patients were found to have noncaseating
granulomas on biopsy consistent with sarcoid . -
pubmed
Age , systemic symptoms , findings on chest X - ray or magnetic resonance imaging ( MRI ) , type of
ventricular arrhythmia , RV function , ECG abnormalities , and the presence or duration of late potentials did not discriminate between sarcoid and
ARVD / C.
Left ventricular dysfunction ( ejection fraction & lt;50 % ) was present in 3/3
patients with
cardiac sarcoid , but only 2/17 remaining patients with definite or probable
ARVD / C ( P = 0.01 ) . -
pubmed
CONCLUSIONS : In this prospective study of consecutive
patients with suspected
ARVD / C evaluated by a standard protocol including biopsy , the incidence of
cardiac sarcoid was surprisingly high ( 15 % ) . -
pubmed
Nontuberculous mycobacteria (
NTM ) are
human opportunistic pathogens with an environmental source of
infection . -
pubmed
AIMS : To evaluate effects of physiotherapeutic intervention in terms of self- and manual mobilization on chest expansion , vital capacity , posture , spine mobility and experienced consequences of the disease in
patients with
ankylosing spondylitis . -
pubmed
METHODS : Thirty - two
men , aged between 23 and 60 years , with
ankylosing spondylitis were randomized to active or no treatment for eight weeks . -
pubmed
CONCLUSION : This study shows that eight weeks of self- and manual mobilization treatment improved chest expansion , posture and spine mobility in
patients with
ankylosing spondylitis . -
pubmed
Postoperative
myocardial damages are a key issue in
patients ' outcome after
hip fracture . -
pubmed
Effect of
alpha lipoic acid on the
tardive dyskinesia and oxidative stress induced by
haloperidol in
rats . -
pubmed
Increased levels of
thiobarbituric acid reactive products are found in the cerebrospinal fluid and plasma of
patients treated with neuroleptics , especially those with
movement disorders . -
pubmed
Infestation by
Pyemotes tritici ( Acari , Pyemotidae ) causes
death of stingless bee colonies ( Hymenoptera : Meliponina ) . -
pubmed
Anaplasma phagocytophilum is the recently designated name replacing three species of granulocytic bacteria ,
Ehrlichia phagocytophila ,
Ehrlichia equi and the agent of
human granulocytic ehrlichiosis , after the recent reorganization of the families Rickettsiaceae and Anaplasmataceae in the order Rickettsiales . -
pubmed
Tick - borne fever (
TBF ) , which is caused by the prototype of
A. - pubmed
Until the discovery of
human granulocytic anaplasmosis (
HGA ) in the USA in 1994 , these organisms were thought to be distinct species of bacteria infecting specific domestic animals and free - living reservoirs . -
pubmed
Ruminants with
TBF and
humans with
HGA develop severe
febrile reaction ,
bacteraemia and
leukopenia due to
neutropenia ,
lymphocytopenia and
thrombocytopenia within a week of exposure to a
tick bite . -
pubmed
Because of the severe
haematological disorders lasting for several days and other adverse effects on the host 's immune functions , infected animals and
humans are more susceptible to other
infections . -
pubmed
A 52 - year - old
man had progressively worsening right
knee pain and
swelling of 3 years ' duration that had been treated conservatively for 6 months . -
pubmed
Axillary lymph node samples derived from
breast cancer patients were measured by Raman microspectroscopy . -
pubmed
The primary end - point -- mean 4 - year
GFR by aMDRD -- ascribed " 0 " to
patients who experienced
death or graft loss after 2 years . -
pubmed
METHODS : This study included 110
patients with
spinal TB and 102 volunteers as controls . -
pubmed
OBJECTIVES : The aim of this randomized controlled study was to cephalometrically assess possible changes in craniofacial morphology associated with long - term use of an adjustable oral - appliance compared with continuous positive airway pressure ( CPAP ) in
patients with the
obstructive sleep apnea / hypopnea syndrome (
OSAHS ) . -
pubmed
Fifteen
sheep with
anthracycline - induced
NICM were assigned to catheter - based , transendocardial injections of allogeneic MPC ( n = 7 ) or placebo ( n = 8) , under electromechanical mapping guidance . -
pubmed
Cell transplantation was associated with 1
death late in follow - up , compared with 3 early
deaths among placebo
animals . -
pubmed
Fourteen
patients with proven
neuroborreliosis served as the control group . -
pubmed
All
EBV cases had a
pleocytosis with significantly increased mononuclear leukocytes as compared to the
neuroborreliosis group ( median 99 % interquartile range ( 96 - 100 % ) versus 90 % ( 86 - 97 % ) . -
pubmed
Enterotoxigenic
Escherichia coli (
ETEC ) is recognized to be a common cause of
acute watery diarrhea in children from developing countries . -
pubmed
MATERIALS AND METHODS : We retrospectively evaluated the pre - operative studies of 60
patients with primary ( n=56 ) and secondary ( n=4 )
hyperparathyroidism . -
pubmed
We performed subcellular fractionation of
human endothelial cells (
EA.hy926 ) after a challenge with
dengue virus serotype-2 (
DEN-2 ) at multiplicity of
infection ( MOI ) of 10 for 2 h. The cells were fractionated into four fractions including cytosol , membrane / organelle , nucleus and cytoskeleton , and their purity was nicely confirmed by immunofluorescence staining of markers for individual subcellular compartments . -
pubmed
METHODS : Procedural billing codes and the electronic medical records of
patients undergoing revascularization for
carotid artery stenosis from February 2007 through March 2010 were used for data collection . -
pubmed
The
carotid artery stenosis was symptomatic in 42 % of these
patients . -
pubmed
Clinical , electrophysiological , and MRI findings in
patients with
cerebellar ataxia and a bilaterally pathological head - impulse test . -
pubmed
A significant number of
patients with
bilateral vestibulopathy suffer from
cerebellar ataxia and central vestibular symptoms and vice versa . -
pubmed
We examined 31
patients presenting with the combination of gait and stance
ataxia , cerebellar ocular motor signs , and a bilaterally pathological head - impulse test (
HIT ) . -
pubmed
Twenty - three
patients had evidence of
polyneuropathy ( predominantly mixed sensorimotor involving
axonal loss and
demyelination ) and twenty of
hypoacusis ( 1 unilateral and 19 bilateral ) . -
pubmed
Voxel - based morphometry comparing local gray matter brain volume between
patients and controls revealed
cerebellar atrophy involving both the vermis and the hemispheres . -
pubmed
This
multisensory syndrome is most likely caused by a
neurodegenerative disorder affecting different systems , leading to severe impairment of affected
patients . -
pubmed
Hepatoprotective activity of the
Phyllanthus species on
tert - butyl hydroperoxide (
t - BH)-induced
cytotoxicity in
HepG2 cells . -
pubmed
BACKGROUND :
Phyllanthus (
Euphorbiaceae ) species have long been used in folk medicine to treat various pathological conditions including
liver diseases . -
pubmed
MATERIALS AND METHODS : The extracts were evaluated for hepatoprotective activity against
tert - butyl hydroxide (
t - BH)-induced
cytotoxicity using
human hepatocarcinoma cells (
HepG2 cell line ) . -
pubmed
Minimal - invasive magnetic heating of
tumors does not alter intra - tumoral nanoparticle accumulation , allowing for repeated therapy sessions : an in vivo study in
mice . -
pubmed
First Report of Intestinal
Myiasis Due To
Eristalis tenax in Iran . -
pubmed
Intestinal
myiasis caused by
E. - pubmed
We report the case of a 43 - years - old
man with a painful
tumefaction of the left hypothenar region . -
pubmed
The
patient underwent surgery to resolve the
ulnar nerve compression and revascularise the artery . -
pubmed
Dietary
fatty acids modulate liver mitochondrial
cardiolipin content and its
fatty acid composition in
rats with
non alcoholic fatty liver disease . -
pubmed
We determined the content of mitochondrial membrane phospholipids from
rats with
non alcoholic liver steatosis , with a particular attention for
cardiolipin ( CL ) content and its
fatty acid composition , and their relation with the activity of the mitochondrial respiratory chain complexes . -
pubmed
The
Pasteurella multocida toxin : a new paradigm for the link between
bacterial infection and
cancer . -
pubmed
The concept that
bacterial infection could cause
cancer has only recently become accepted because of the strong epidemiological and molecular evidence for a major carcinogenic role played by
Helicobacter pylori . -
pubmed
The diagnosis of
tuberculosis is seriously hampered in the absence of standard biosafety laboratory facilities for specimen concentration and
Mycobacterium tuberculosis culture . -
pubmed
All these factors were significantly upregulated in the
POEMS syndrome patients . -
pubmed
Chyloperitoneum ,
chylothorax and
lower extremity lymphedema in
woman with
sporadic lymphangioleiomyomatosis successfully treated with
sirolimus : a case report . -
pubmed
Recent studies report effectiveness of
sirolimus in
LAM patients . -
pubmed
We report the case of a 45 - year - old
woman with sporadic
LAM , successfully treated with
sirolimus , in whom the first manifestation of the disease was
chyloperitoneum and after three and nine years , respectively ,
lymphedema of the left lower extremity and right sided
chylothorax occurred . -
pubmed
This paper examines the case of a 37 - year - old male
patient reported to have developed
noncardiogenic pulmonary edema after intravenous injection of
gadobutrol during MRI . -
pubmed
The clinical presentation varies with the amount of
triglycerides in the blood and completely resolves with lowering
triglyceride levels , making this condition transient with no
visual symptoms ; CASE REPORT : A 46 - year old white
man presented with
lipemia retinalis and , hours later , to the Emergency department with acute
pancreatitis secondary to
hypertriglyceridemia ; CONCLUSION :
Lipemia retinalis warrants an immediate complete blood count and lipid panel to Determine
triglyceride levels with referral to a primary care provider . -
pubmed
The Minimal Inhibitory Concentration ( MIC ) varied from 0.5 to 1.5 mg / mL and 1.25 to 2 mg / mL for
yeast and
bacterial strains , respectively . -
pubmed
The optical density value in
rats with
brain ischemia significantly increased , compared with sham one ( P<0.05 ) . -
pubmed
PARTICIPANTS :
Women with stress or mixed
urinary incontinence with predominantly
stress urinary incontinence . -
pubmed
A 72 - year - old
man presented with
palpitation ,
dyspnea , and
chest discomfort . -
pubmed
[ A case in which
XELOX plus
bevacizumab chemotherapy was effective in an elderly
patient with
heart failure and
multiple liver metastases after sigmoidectomy ] . -
pubmed
A 75 - year - old
woman with a chief complain of
anal pain visited the emergency department . -
pubmed
Six days after drainage , the
patient 's condition progressed to acute
respiratory failure due to
heart failure , and ventilator support was provided temporarily . -
pubmed
Twenty - five
patients with
epidermal cysts , which were 0.5 to 1.5 cm in diameter , non - inflamed , and freely movable , were treated . -
pubmed
Helicobacter pylori and skin
autoimmune diseases . -
pubmed
In 150
patients with amnestic mild
cognitive impairment , WMHs were quantified with the use of a semiautomated volumetric method . -
pubmed
AIMS : We present an audit report and a systematic review of published observational studies on PIROLA occurrence in
acute ischaemic stroke patients . -
pubmed
METHODS : Clinical files of
patients treated in the
stroke unit of Bourg - en - Bresse General Hospital ( France ) from January 2010 to December 2012 were reviewed , and MEDLINE ( inception to May 2013 ) were searched and bibliographies / citations of retrieved articles examined for evidence of PIROLA . -
pubmed
The systematic review identified 27 studies , totalising with ours , over 9050 acute
ischaemic stroke patients from 12 countries , among whom 100 ( cumulative incidence rate : 17 % ; 95 % confidence intervals : 8 - 26 ) , developed a PIROLA within 6 - 240 minutes of receiving r - tPA , 0 - 100 % of them occurring among
patients on ACEI . -
pubmed
CONCLUSIONS : About 17 % acute
ischaemic stroke patients receiving r - tPA develop
PIROLA , occurring essentially among those on concomitant ACEI . -
pubmed
Vibrio cholerae O1 , the causative agent of the disease
cholera , has two biotypes namely the classical and El Tor . -
pubmed
cholerae strains into biotype does not alter the clinical management of
cholera but is of immense public health and epidemiological importance in identifying the source and spread of
infection , particularly when
V. - pubmed
METHODS : Overall survival of
patients who had lobectomy for any stage
non - small cell lung cancer without previous chemotherapy or radiation from 1996 to 2008 was evaluated using the Kaplan - Meier method and multivariate Cox analysis . -
pubmed
Thoracotomy
patients had larger
tumors ( 3.9 + -2.3 versus 2.8 + -1.5 cm , p<0.0001 ) , and more often had higher stage
cancers ( 50 % [ n=237 ] versus 71 % [ n=435 ] stage I , p<0.0001 ) compared with VATS
patients . -
pubmed
In a cohort of 560
patients ( 311 VATS , 249 thoracotomy ) who were assembled using propensity scoring and were similar in age , stage ,
tumor size , and sex , the operative approach did not impact survival ( p=0.5 ) , whereas increasing age ( HR 1.02 per year , p=0.01 ) , pathologic stage ( HR 1.44 per stage , p<0.0001 ) , and male sex ( HR 1.29 , p=0.01 ) predicted worse survival . -
pubmed
Relation of epicardial fat to central aortic pressure and left ventricular diastolic function in
patients with known or suspected
coronary artery disease . -
pubmed
We studied 134 consecutive
patients undergoing left - sided cardiac catheterization for
coronary artery disease (
CAD ) and examined the relation of epicardial fat volume measured by multi - detector computed tomography to ascending aortic pressure and LV ejection fraction determined by cardiac catheterization as well as indices of LV diastolic function assessed by Doppler echocardiography [ early diastolic mitral annular velocity ( e ' ) and a ratio of early diastolic mitral inflow to annular velocities ( E / e ' ) ] . -
pubmed
UNLABELLED :
Impaired tactile acuity in
people with
chronic pain conditions has been suggested to reflect altered cortical representation of the painful body part , and treatments that aim to improve tactile acuity in these conditions have shown clinical benefit . -
pubmed
The aim of this review was to systematically evaluate the literature and use meta - analysis to establish whether tactile acuity is altered in
people with
chronic non - neuropathic pain . -
pubmed
We systematically searched the literature for studies that investigated tactile acuity in
people with
chronic non - neuropathic pain and compared it to an appropriate control group . -
pubmed
PERSPECTIVE : This systematic review synthesizes the evidence for
tactile acuity deficits in
people with
chronic non - neuropathic pain . -
pubmed
Many researchers have explored the effects of perinatal programming on the
human neurodevelopment , and some aspects of the brain structure and/or functioning ( such as cognitive function , physiological reactivity to stress , and the risk for
behavioral disorders or psychopathology ) were shown to be modifiable by the exposure to certain adverse events early in life such as
neonatal infections , exposure to gestational psychosocial stress , nutrition during gestation , exposure to drugs , or
tobacco smoking during pregnancy . -
pubmed
OBJECTIVE : To develop a decision analytic model to calculate outcomes after treatment of
cerebral aneurysms in elderly
patients . -
pubmed
PURPOSE : This cross - sectional study aimed to estimate the prevalence of
Chlamydia trachomatis ( CT ) infection alone and in combination with
human papillomavirus (
HPV ) . -
pubmed
Furthermore , the study investigates whether the
CT infection increases the risk of contracting
HPV and whether the presence of both pathogens is associated with a higher prevalence of
cervical lesions . -
pubmed
The higher prevalence of
LSIL in women co - infected with
HPV and
CT is possibly due to
HPV . -
pubmed
CONCLUSION :
CT infection was more prevalent in younger women aged up to 32 years , who had an early onset of reproductive activity and a history of having had multiple sexual partners lifelong may be at a greater risk of acquiring
infection of the genital tract by
C. - pubmed
PATIENT SAMPLE : All
patients who underwent palliative surgery for the treatment of a
neoplastic spine lesion in our institution between 2005 and 2012 . -
pubmed
OUTCOME MEASURES : Percentage of
patients who underwent surgery as an emergency for acute
fracture or rapid neurological decline . -
pubmed
METHODS : We retrospectively reviewed the data of all
patients who underwent palliative surgery for the treatment of a
neoplastic spine lesion from
solid cancer or
multiple myeloma , in our institution between January 2005 and December 2012 . -
pubmed
The
cancer was known for 224
patients , while the lesion revealed the disease for the other 93
patients . -
pubmed
The percentage of
patients with known
cancer operated as an emergency in our institution decreased significantly between 2005 and 2012 ( p = 0.0006 ) . -
pubmed
Compound 4 exhibited
cytotoxicity against the cervical
carcinoma cell line (
CaSki ) with an IC50 value of 2.4 muM , and 6 showed toxicity toward
brine shrimp Artemia salina with an LC50 value of 2.0 muM. -
pubmed
Patients may also have questions regarding complementary and alternative medicines , so clinicians should know which options are most promising for
patients with
MS . -
pubmed
The spread of
dengue fever depends mainly on the availability of favourable breeding sites for its mosquito vectors around
human dwellings . -
pubmed
Here we tested on Genetic Absence
Epilepsy Rats from Strasbourg ( GAERS ) the consequences of acute and chronic exposure to
caffeine on the expression of spike - and - wave discharges ( SWDs ) . -
pubmed
In elderly or comorbid
patients diagnosed with
small renal masses , competing cause mortality seems to exceed
cancer - specific mortality at short- and intermediate - term follow up . -
pubmed
According to the current available evidence , active surveillance is a safe and reasonable option for
patients with
renal tumors & lt;=4 cm ( cT1a ) and short life expectancy . -
pubmed
Renal
tumor biopsy is useful in the clinical work - up of patients who are candidates for active surveillance , in order to improve
patient selection based on
tumor histological characterization . -
pubmed
Despite the proof of safety offered by expectant management for small renal masses in selected
patients , further prospective studies with longer follow up are required in order to confirm the indications and long - term oncological outcomes of active surveillance protocols for
renal tumors . -
pubmed
Coronary stent selection and optimal course of dual antiplatelet therapy in
patients at high
bleeding or
thrombotic risk : navigating between limited evidence and clinical concerns . -
pubmed
Fifty - nine
preeclamptic patients , 60 healthy pregnant
women and 56 healthy nonpregnant
women were involved in this case - control study . -
pubmed
It is well known that long - term exposure to
arsenite leads to
human skin cancer , but the underlying mechanisms of
carcinogenesis remain obscure . -
pubmed
In vivo
wound healing activity of gels containing
Cecropia pachystachya leaves . -
pubmed
METHODS : The
wound healing activity of the gels was evaluated for 21 days , using the excision model in
rats followed by histopathological and histomorphometric analysis . -
pubmed
Evaluation of Executive Functions in
Patients With Childhood
Absence Epilepsy . -
pubmed
OBJECTIVE : The aim of this study was to evaluate the executive function of
patients with typical
absence epilepsy . -
pubmed
CONCLUSION : Long - term risk for
learning impairments , failure in executive abilities , and short - term memory and
attention disorders can occur in
children with
absence epilepsy . -
pubmed
RESULTS : A total of 44
ECM patients were included in our analysis . -
pubmed
METHODS : Seventy - one cases of
patients with
diabetic foot ulcers and 53 cases of
nondiabetic ulcers were enrolled . -
pubmed
Lyme disease ,
West Nile virus (
WNV ) , and other vector - borne diseases were identified as priority emerging non - enteric
zoonoses in Canada in a prioritization exercise conducted by public health stakeholders in 2013 . -
pubmed
Lyme disease is emerging in Canada due to range expansion of the tick vector , which also signals concern for the emergence of
human granulocytic anaplasmosis ,
babesiosis , and
Powassan virus . -
pubmed
Prolongation of atrio - ventricular node conduction in a
rabbit model of
ischaemic cardiomyopathy : Role of
fibrosis and connexin remodelling . -
pubmed
Only one type of
HPV was detected in 87.7 % of the
E6 / E7 mRNA positive cases . -
pubmed
Are aerobic interval training and continuous training isocaloric in
coronary artery disease patients ? -
pubmed
Chronic Kidney Disease , But Not
Diabetes , Can Predict 30 - Day Outcomes in
Patients with ST - Elevation
Myocardial Infarction after Primary Percutaneous Coronary Intervention : A Single - Center Experience . -
pubmed
BACKGROUND :
Patients with
acute coronary syndrome and
impaired renal function have been shown to have high mortality . -
pubmed
METHOD : This study enrolled 512
STEMI patients who received primary percutaneous coronary intervention . -
pubmed
Patients were divided into 4 groups including group 1 :
patients without
DM or
CKD ( nDM - nCKD ) ; group 2 :
patients with
DM but without
CKD (
DM - nCKD ) ; group 3 :
patients with
CKD but without
DM ( nDM -
CKD ) ; group 4 :
patients with
DM and
CKD (
DM -
CKD ) . -
pubmed
RESULTS : The
patients in both the nDM -
CKD group and DM -
CKD group had higher incidences of
hypotension , intra - aortic balloon counterpulsation use , and
respiratory failure ( p & lt ; 0.005 ) . -
pubmed
The
patients with
CKD stage 3 and 4 had longer hospital stay and higher 30 - day mortality rates ( p & lt ; 0.001 ) . -
pubmed
CONCLUSIONS :
STEMI patients with
impaired renal function , but not
DM , had significantly longer hospital stay and higher 30 - day mortality rates . -
pubmed
Influence of Statin Pretreatment on Initial Neurological Severity and Short - Term Functional Outcome in
Acute Ischemic Stroke Patients : The Fukuoka
Stroke Registry . -
pubmed
This study aimed at determining these associations in
ischemic stroke patients . -
pubmed
METHODS : Among
patients registered in the Fukuoka
Stroke Registry from June 2007 to October 2014 , 3,848
patients with
ischemic stroke within 24 h of onset , who had been functionally independent before onset , were enrolled in this study . -
pubmed
The frequency of mild
neurological symptoms was significantly higher in
patients with pre -
stroke statin treatment ( 64.1 % ) than in those without the treatment ( 58.3 % , p & lt ; 0.01 ) . -
pubmed
Sensitivity analysis in
patients with
dyslipidemia ( n = 1,998 ) also showed the same trend between pre -
stroke statin treatment and mild
neurological symptoms ( multivariable - adjusted OR 1.26 ; 95 % CI 0.99 - 1.62 ; p = 0.06 ) . -
pubmed
Continuation of statin treatment , however , was significantly associated with favorable functional outcome among
patients with pre -
stroke statin treatment ( multivariable - adjusted OR 2.17 ; 95 % CI 1.16 - 4.00 ; p = 0.02 ) . -
pubmed
CONCLUSIONS : Pre -
stroke statin treatment in
ischemic stroke patients was significantly associated with mild neurological symptoms within 24 h of onset . -
pubmed
Pre -
stroke statin treatment per se did not significantly influence the short - term functional outcome ; however , continuation of statin treatment during the acute stage of
stroke seems to relate with favorable functional outcome for
patients with pre -
stroke statin treatment . -
pubmed
Severe
cytokine release syndrome (
sCRS ) and grade & gt;=3
neurotoxicity were observed in 13 and 28 % of all
patients , respectively . -
pubmed
We demonstrate how measurement of changes in tissue density with DHM , based on refractive index measurement , can quantify inflammatory alterations , without staining , in different layers of colonic tissue specimens from
mice and
humans with
colitis . -
pubmed
All
patients admitted to Christian Medical College and Hospital , Ludhiana , who received a permanent pacemaker for
bradyarrhythmias were included in the study . -
pubmed
During the entire study period
death occurred in 7.1 %
patients . -
pubmed
BACKGROUND : Early cardiac surgery may have a trade - off between stabilized hemodynamics with controlled
infection and a risk of peri - operative
death in
patients with
infective endocarditis (
IE ) complicated with
cardio - embolic strokes . -
pubmed
METHODS : We retrospectively studied clinical characteristics and outcomes in 68 consecutive
patients with
IE ( mean age , 58 + -3years , 62 % male ) who admitted in our institute during June 2013 and August 2015 . -
pubmed
RESULTS : Cardio - embolic
strokes were noted in 37 % of
patients ( n=25 ) with
IE and overall in - hospital mortality was 4 times higher in IE with cardio - embolic
strokes than IE with an absence of
strokes ( n=43 ) ( 20 % vs. 4.7 % , p=0.045 ) . -
pubmed
Bacteremia of
Staphylococcus aureus ( p=0.021 ) and a complication of
cardio - embolic strokes ( p=0.031 ) were independently associated with in - hospital
death in those with
IE . -
pubmed
The assessment of seafarers ' knowledge , attitudes and practices related to
STI /
HIV /
AIDS in northern Morocco . -
pubmed
Neutrophils , an important type of
human immune cells , are involved in host defense against
infections . -
pubmed
[ Evaluation and treatment of sleep problems in
children diagnosed with
attention deficit hyperactivity disorder : an update of the evidence ] . -
pubmed
INTRODUCTION :
Attention deficit hyperactivity disorder (
ADHD ) affects approximately 5 % of all
children and adolescents , and these patients frequently suffer from
sleep problems . -
pubmed
DEVELOPMENT : Sleep problems in
children with
ADHD include altered sleep and specific disorders per se or that may be due to comorbid
psychiatric disorders or to the stimulants they receive as treatment for their
ADHD . -
pubmed
Today , an evaluation of the sleep conditions in
children with
ADHD is recommended before starting pharmacological treatment . -
pubmed
Atomoxetine and
melatonin are therapeutic alternatives for
children with
ADHD and more severe
sleep problems . -
pubmed
CONCLUSIONS : It is important to evaluate sleep in
children who present symptoms suggestive of
ADHD , since problems during sleep can play a causal role or exacerbate the clinical features of
ADHD . -
pubmed
Correct evaluation and treatment of
sleep disorders increase the family 's and the
child 's quality of life and can lessen the severity of the symptoms of
ADHD . -
pubmed
METHODS : This retrospective study was performed on 26
patients with
muscle herniation confirmed by surgery . -
pubmed
Much current
TB vaccine research focuses on engineering live mycobacteria to interfere with phagosome biology and host intracellular pathways including apoptosis and autophagy , with candidates such as BCG Deltazmp1 , BCG DeltaureC::hly , BCG::ESX-1Mmar ,
Mtb DeltaphoP DeltafadD26 ,
Mtb DeltaRD1 DeltapanCD and
M. - pubmed
It can be concluded that the dose of
enrofloxacin used in the present study can be administered to contain
infections caused by
P. - pubmed
Highly pathogenic
influenza viruses pose a serious public health threat to
humans . -
pubmed
PRESENTATION OF CASE : A 62 - year - old
man with a two - day history of
epigastric pain was admitted at emergency department . -
pubmed
Simultaneous handling of
celiac axis stenosis is still prone to controversy : no
relapse of
aneurysm have been reported in
patients with
celiac axis stenosis at long - term follow - up , simultaneous treatment should be reserved when angiography is alarming for likely
hepatic or duodenal ischemia . -
pubmed
Experiments with the newly synthesized fluorescent dye
1 - N - methylamino-5 - isocyanonaphthalene (
MICAN ) served to test its
cytotoxicity on
human HaCaT keratinocyte cell cultures . -
pubmed
Comparative Metabolomics Elucidates Postprandial Metabolic Modifications in Plasma of Obese
Individuals with
Metabolic Syndrome . -
pubmed
This study investigated the dynamic metabolic profile shift following the ingestion of low - fat milk or an isocaloric volume of
rice milk in
obese individuals with
metabolic syndrome (
MetS ) . -
pubmed
The comprehensive time - course metabolic profiling in
MetS participants indicated that the postprandial metabolic profiles distinguish low - fat milk and
rice milk consumption in a time - dependent manner . -
pubmed
Nutrient deficiency promotes male - biased apparent sex ratios at the ramet level in the dioecious plant
Myrica gale var . - pubmed
Retrospective evaluation of a decision - support algorithm ( MIPOGG ) for genetic referrals for
children with
neuroblastic tumors . -
pubmed
A challenge for clinicians is the identification of
children with
neuroblastoma who require genetics evaluation for underlying
cancer predisposition
syndromes (
CPS ) . -
pubmed
OBJECTIVES : A recent randomized study of fractionated radiation therapy ( RT ) examining 44 subtotally resected / recurrent benign
meningioma patients revealed that at median follow - up of 17.1 years , the risk of
stroke following proton - photon RT was 20.5 % ; the average
stroke developed 5.6 years following RT completion ( Sanford et al . -
pubmed
RESULTS : Fourteen studies met inclusion criteria ; 1431
patients received photon - based SRS for
meningioma with a sufficient long - term follow - up . -
pubmed
CASE REPORT A 30 - year - old
man with multiple admissions for chronic intermittent colicky
abdominal pain since childhood , was admitted for symptoms suggestive of
proximal small bowel obstruction . -
pubmed
The
patient was administered
imatinib for 2 months , which caused the
tumor to shrink , and extended left lobectomy was performed . -
pubmed
RESULTS : The survival experience of 2493
TB patients was investigated 73.7 % of which were pulmonary type . -
pubmed
The incidence rate of
death among
patients during the treatment courses was 0.99 ( 95 % confidence interval : 0.84 - 1.1 ) per 100 person - months . -
pubmed
Controlling the confounders , the incidence ( 95 % confidence interval ) of
death was significantly higher among men ( HR=1.8 ; 1.2 - 2.6 ) ,
diabetic patients ( HR=1.7 ; 1.2 - 2.6 ) ,
cancerous patients ( HR=4.8 ; 2.6 - 8.8 ) and
HIV positive patients ( HR=22.1 ; 7.3 - 66.4 ) . -
pubmed
These
goats were brought to the Kafkas University Wildlife Rescue and Rehabilitation Center ( Kars , Turkey ) for various reasons such as
traffic accidents or
firearm injury , but either could not be saved or were euthanized . -
pubmed
Preventive Effects and Mechanisms of
Garlic on
Dyslipidemia and Gut Microbiome Dysbiosis . -
pubmed
Taken together , our data demonstrated that whole
garlic supplementation could meliorate the HFD - induced
dyslipidemia and disturbance of gut microbiome . -
pubmed
These findings reveal novel mechanisms controlling myocardial remodeling and may provide new clues for strategies to interfere cardiac remodeling - related
heart disorders in
humans . -
pubmed
Water maze was conducted to evaluate spatial learning and memory ability of
middle cerebral artery occlusion (
MCAO )
rats . -
pubmed
Patients with
cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy (
CADASIL ) can develop multiple border - zone
infarcts due to
hypotension ,
hypovolemia , or surgery . -
pubmed
We report the case of a 41 - year - old
woman with
CADASIL who developed multiple border - zone
infarcts due to
influenza A virus infection . -
pubmed
Our case demonstrates that
infectious conditions such as
influenza A can trigger
multiple border - zone infarctions in
patients with
CADASIL . -
pubmed
MATERIAL AND METHODS : 40
patients with
vulvar cancer and SLNB between 2008 and 2018 were retrospectively reviewed . -
pubmed
Subsequently , long - term
patient follow - up was performed with analysis of complications ,
relapse and mortality . -
pubmed
In 3 out of 25
patients with lateral
tumour lesions drainage was bilateral and in 2 out of 15 with midline lesions drainage was unilateral . -
pubmed
Phenotypical and functional abnormalities of circulating neutrophils in
patients with
beta - thalassemia . -
pubmed
Patients with
beta - thalassemia present variable clinical severity ranging from asymptomatic trait to severe transfusion - dependent
anemia and
multiple organs complications . -
pubmed
Despite some abnormalities reported for
thalassemia patient 's immune system , few data exist on the characterization of
human neutrophils in
beta - thalassemia . -
pubmed
The aim of this study was to investigate the phenotype and function of circulating neutrophil subsets in
patients with
beta - thalassemia major and with
beta - thalassemia intermedia divided in transfusion - dependent and non - transfusion - dependent . -
pubmed
By determining Pearson 's correlation coefficient and using StarBase , DIANA - LncBase , and
Human MicroRNA Disease Database ( HMDD ) , the
AD immune - related ceRNA network was generated . -
pubmed
It can easily penetrate into
tumor tissues , target an epitope inaccessible to mAb and be manufactured in
bacteria for a low cost . -
pubmed
They also bound to the three different
human cancer cell lines , but not to the two cell lines as negative controls . -
pubmed
Two of them were tested for their anti -
tumor effect in vivo and showed the anti -
tumor activity in a
mouse xenograft model for
human lung cancer . -
pubmed
They could be potential therapeutics for the treatment of different
human cancers . -
pubmed
Oral anti - mycobacterial treatment of
Crohn ' s disease (
CD ) is limited by the low aqueous solubility of drugs , along with the altered gut conditions of
patients , making uncommon their clinical use . -
pubmed
Permeability across
Caco-2 cell monolayers and
cytotoxicity and uptake in
human macrophages was also determined . -
pubmed
METHODS : We recruited 94
participants : 50 with
TBI only (
TBI - only ) and 44 with
TBI and
PNES (
TBI +
PNES ) . -
pubmed
Participants completed mood ( Beck Depression Inventory - II ) ,
anxiety ( Beck Anxiety Inventory ) , and
posttraumatic stress disorder (
PTSD ) symptom ( PTSD Checklist - Specific Event ) assessments before undergoing functional magnetic resonance imaging during an acute psychosocial stress task . -
pubmed
Association of
sleep - disordered breathing and
wound healing in
patients with
diabetic foot ulcers . -
pubmed
However , whether
SDB has an adverse impact on
wound healing in
patients with
diabetic foot ulcers (
DFUs ) is uncertain . -
pubmed
The purpose of this study was to investigate the association of SDB with
wound healing in
patients with
DFUs . -
pubmed
METHODS : A total of 167
patients with
DFUs were enrolled between July 2013 and June 2019 at West China Hospital to assess the association of
SDB with
wound healing ,
ulcer recurrence , and all - cause mortality . -
pubmed
CONCLUSIONS :
SDB is highly prevalent in
patients with
DFUs but its severity , as conventionally measured by AHI , is not associated with
wound healing . -
pubmed
Sleep fragmentation and
hypoxemia are stronger predictors of poor
wound healing , high
ulcer recurrence and increased risk of
death in
patients with
DFUs . -
pubmed
Arteriolar hyalinosis is related to rapid
GFR decline and long - standing
GFR changes observed on renal biopsies in normo - microalbuminuric type 2 diabetic
patients . -
pubmed
METHODS : We evaluated 22
type 2 diabetic patients with normo- or
microalbuminuria who took part in the previous study , to clarify which renal histological factors were associated with changes in UAE and the
glomerular filtration rate (
GFR ) during 11.0 + - 3.0 years of follow - up . -
pubmed
The
GFR at follow - up in
patients with
IAH > = 2.0 was significantly decreased from baseline ( p = 0.042 ) and significantly lower than that of the
patients with
IAH < 2.0 ( p = 0.026 ) , which did not decrease significantly from baseline . -
pubmed
The auditory system appears particularly sensitive , as previous work has shown that developmental
PCB exposure causes both
hearing loss and gross disruptions in the organization of the
rat auditory cortex . -
pubmed
PURPOSE : Primarily , to investigate the effect of high intake of
cod ( lean fish ) or
salmon ( fatty fish ) on serum concentration of total
neopterin , a marker of cellular immune activation that is associated with
cardiovascular disease . -
pubmed
METHODS : In this randomised clinical trial , 63
participants with
overweight /
obesity consumed 750 g / week of either
Atlantic cod ( N = 22 ) or
Atlantic salmon ( N = 22 ) or were instructed to continue their normal eating habits but avoid fish intake ( Control group , N = 19 ) for 8 weeks . -
pubmed
The purpose is to compare clinical outcomes and complication rates after surgery in
patients with
shoulder arthropathy treated with stemless or conventional stemmed shoulder prosthesis . -
pubmed
Thirty
patients with mild to severe essential
hypertension satisfactorily controlled by twice - daily
sotalol therapy entered a double - blind , crossover study comparing the efficacy , tolerability , and safety of their usual twice - daily
sotalol administration with the same dosage given once daily . -
pubmed
Brain proteins were analyzed in supra- and infratentorial structures of 6
patients dying from
liver failure . -
pubmed
An equal number of
patients , lacking any evidence of
liver disease or
neurological disorder , served as controls . -
pubmed
This report describes the results of language therapy initiated 1 to 6 years after the onset of
aphasia in 14
patients . -
pubmed
Similar results were obtained in experiments with brain extracts from
patients with
subacute sclerosing panencephalitis . -
pubmed
Effects of mild physical activity ,
atenolol and the combination on ambulatory blood pressure in
hypertensive subjects . -
pubmed
DESIGN AND METHODS : In 12
hypertensive subjects ( mean age : 40.3 years ) a prospective randomized Latin square - design trial was performed with three treatments : physical training and placebo tablets ;
atenolol 50 mg once a day and inactivity ; and physical training and
atenolol 50 mg once a day . -
pubmed
Relapse factors during maintenance therapy of
acute lymphoblastic leukemia in
children . -
pubmed
The risk of infectious complication in our adolescent population prompted a recommendation for aggressive preventive measures , including documentation of recent negative cultures for
Neisseria gonorrhoeae and
Chlamydia . -
pubmed
Reinduction of
melatonin production by
isoproterenol ( 2 mg / kg
body weight ) administration to acutely light - exposed
animals during late darkness was prevented by
cycloheximide , but not by
actinomycin D administration . -
pubmed
Incessant monomorphic
ventricular bigeminy was studied in a young
patient with no
organic heart disease . -
pubmed
It arose in a 62 year old
man and was diagnosed on the basis of a bilateral
pleural effusion , which showed many plasma cells and plasmoblasts . -
pubmed
The
patient also presented multiple
osteolytic lesions , no
adenopathies , or signs of hepatic or splenic infiltration . -
pubmed
Experimental results were correlated with postoperative catheterization data from 19
patients with
tricuspid atresia who had the Fontan operation . -
pubmed
Encephaloborreliosis is described in a 16 year old
patient . -
pubmed
Perineal hernia repair in the
dog by transposition of the internal obturator muscle . -
pubmed
A modified technique for transposition of the internal obturator muscle was used to repair
perineal hernias in 100
dogs . -
pubmed
Trifluoperazine does not affect
doxorubicin cardiotoxicity in the
rat . -
pubmed
Analgesic effect and bioavailability of oral
ketogan given as tablets or mixture to
patients with
chronic pain of malignant origin . -
pubmed
Thirteen
cancer patients with moderate to severe
chronic pain of malignant origin on treatment with
Ketogan tablets were included in an open non - randomized cross - over study comparing the analgesic effect , side effects and serum concentrations of
Ketogan tablets and mixture . -
pubmed
Circulating lymphocyte populations and autoantibodies in
non - obese diabetic (
NOD )
mice : a longitudinal study . -
pubmed
Several previous observations indicate a role for the immune system in the pathogenesis of
insulin - dependent diabetes mellitus (
IDDM ) in
non - obese diabetic (
NOD )
mice . -
pubmed
In order to assess the status of the immune system in this model of spontaneous
diabetes we studied the phenotype of circulating lymphocytes and the humoral autoimmunity to islet cells in non - diabetic NOD
mice at various ages . -
pubmed
Lymphocyte numbers were low in young NOD
mice ( age less than 160 days ) as compared with other
strains of
mice and increased later to reach values in or above the range of controls . -
pubmed
Antibodies to surface
antigens of
rat insulinoma cells were virtually absent in young NOD
mice ( 75 - 100 days ) and appeared in 33 to 43 % of the samples from 150 to 185 days old
NOD mice . -
pubmed
The subjects were 97 chronic
prostatitis patients for whom the prostate fluid had been confirmed to contain at least 30 leukocytes per 400 - power magnification field . -
pubmed
In 53.9 % of the
patients who had not been receiving therapy prior to inclusion in this study , the subjective symptoms consisted of
urethral irritation or
irritation upon urination . -
pubmed
Magnetic resonance imaging of chronic
myocardial infarcts in
man . -
pubmed
To evaluate the magnetic resonance imaging ( MRI ) features of
chronic myocardial infarction (
MI ) , 22
patients and several normal
volunteers were studied with a 0.35 - T cryogenic imaging system . -
pubmed
At least one abnormality indicative of prior
infarction was demonstrated on MRI in 20 of the 22
patients . -
pubmed
Wall thinning was seen in 20
patients ; in six of these , the thinning resulted in
aneurysm formation . -
pubmed
[
Systemic lupus erythematosus and anti - native - DNA antibodies measured using
Crithidia luciliae ] . -
pubmed
Experimental studies on the
spitting cobra ophthalmia (
Naja nigricollis ) . -
pubmed
Structural polypeptides of the hamster
strain of
equine herpes virus type 1 : products associated with purification . -
pubmed
[ Effect of intralienal
oxygen injection in experimental
traumatic shock on levels of
phospholipid - P and total
lipids in the blood serum in
dogs ] . -
pubmed
Purified
Trypanosoma cruzi specific glycoprotein for discriminative serological diagnosis of South American
trypanosomiasis (
Chagas ' disease ) . -
pubmed
In a
mouse model , the same test can differentiate between
T cruzi and
T rangeli infections . -
pubmed
Requirement for membrane potential in
Escherichia coli infection by phage T4 . -
pubmed
The phage
infection was strictly dependent on
E. - pubmed
In one
patient with a perforated
peptic ulcer and
tension pneumoperitoneum , an enormous increase in intra - abdominal pressure apparently led to acute
aortic occlusion . -
pubmed
The clinical findings of
aortic occlusion were reproduced in a
canine model by insufflation of air into the abdomen . -
pubmed
[ Effect of aging on blood
catecholamine under 3 conditions of
sodium intake -- comparison between normal subjects and
patients with essential
hypertension ] . -
pubmed
It is proposed that alternative mechanisms for
hepatocyte injury may apply in different chronic
HBV patients , one related to virus replication and one dependent on immunological factors . -
pubmed
Posterior circulation in 82
children of "
moyamoya " disease are studied . -
pubmed
A distal splenorenal shunt was performed electively in 25
patients with
bleeding oesophageal varices . -
pubmed
During the follow - up period ( mean 41 months ) three
patients died , one of
liver insufficiency and two of
cardiac complications . -
pubmed
Two
patients of 17 survivors ( 12 % ) had endoscopically demonstrable
varices . -
pubmed
Even though in certain patients the original selectivity of the shunt is lost it gives a good long - term variceal decompression and certainly is a useful alternative in the treatment of selected good risk
patients for
bleeding oesophageal varices . -
pubmed
Macrophages obtained from
rabbit lungs undergoing BCG - induced chronic
inflammation released more
chromium when incubated in the presence of phagocytosable particles than when incubated under resting conditions . -
pubmed
Fifty consecutive
spinal injury patients who underwent simultaneous EMG of the peri - urethral and perianal striated muscles along with cystometrogram on a multiple channel recorder are analysed . -
pubmed
Work is in progress to improve the techniques and to evaluate the
toxicity of the chemiluminescent material in
animals . -
pubmed
However , in 11/15 ( 73 % )
patients who underwent OGTT before and after surgery , an improvement in
glucose tolerance was observed after
tumor resection . -
pubmed
We report herein the unusual case of a 25 - year - old
man with
CGL in whom
gas gangrene developed , an association which has never before been encountered . -
pubmed
Patients were grouped according to the presence ( n = 31 ) or absence ( n = 65 ) of
multiple organ failure . -
pubmed
The mortality rate in the
patients who developed
multiple organ failure was 42 % vs. only 2 % in those
patients without
multiple organ failure ( p & lt ; .0001 ) . -
pubmed
Comparative characterization of antigenic epitopes in the immunodominant region of the protein encoded by open reading frame 3 in Burmese and Mexican
strains of
hepatitis E virus . -
pubmed
To analyse the effect of
strain - specific sequence variation on the antigenic properties of the protein encoded by the open reading frame 3 ( ORF 3 ) of
hepatitis E virus (
HEV ) , two sets of short overlapping peptides spanning
amino acids 91 to 123 of this protein from
Burmese and Mexican
strains were synthesized and tested with sera obtained from outbreaks of enterically transmitted non - A ,
non - B hepatitis in three different regions of the world ( Mexico , Turkmenistan and Kenya ) . -
pubmed
Each
patient was alert and free of
injury to the globe when evaluated before surgery . -
pubmed
Enrollment of
patients with no light perception or who experienced delay between
injury and treatment may be reasonably considered . -
pubmed
Age - related therapeutic response to antithyroid drug in
patients with
hyperthyroid Graves ' disease . -
pubmed
Recurrence after discontinuation of
methimazole was more frequent in young than in aged
patients . -
pubmed
CONCLUSIONS : Aged
patients with
hyperthyroid Graves ' disease show a more favorable response to antithyroid drugs than young counterparts . -
pubmed
A case of an
adrenal incidentaloma in a 57 - year - old
man with
silent 21 - hydroxylase deficiency is reported . -
pubmed
However , after surgical removal of the
adrenal tumour , the
patient developed acute
adrenal insufficiency . -
pubmed
Dideoxycytidine (
ddC ) is a
nucleoside analogue active against
human immunodeficiency virus and with in vitro activity against
human hepatitis B virus . -
pubmed
Accumulation of
manganese and
copper in pallidum of
cirrhotic patients : role in the pathogenesis of
hepatic encephalopathy ? -
pubmed
Concentrations of
zinc ,
copper and
manganese were measured by atomic absorption spectrometry in samples of globus pallidus obtained at autopsy from 9
patients with
chronic liver disease and an equal number of age - matched controls . -
pubmed
Manganese concentrations were significantly increased several fold ( p & lt ; 0.01 ) in globus pallidus of
liver disease patients accompanied by smaller but significant 2 - fold increases of
copper . -
pubmed
Increased pallidal
manganese offers a cogent explanation for the observed T1 - weighted MRI signal hyperintensity in pallidum of
cirrhotic patients . -
pubmed
Basic research in
Epstein - Barr virus (
EBV ) molecular genetics has provided means to maintain episomes in
human cells , to efficiently deliver episomes with up to 150 kbp of heterologous DNA to
human B lymphocytes , and to immortalize
human B lymphocytes with
EBV recombinants that can maintain up to 120 kbp of heterologous DNA . -
pubmed
EBV - derived vectors are useful for experimental genetic reconstitution in B lymphocytes , a cell type frequently used in establishing repositories of
human genetic deficiencies . -
pubmed
In this study , the urinary free
dopamine excretion ( uDA ) , delivery of
L - dopa to renal proximal tubules ( plasma
L - dopa x
creatinine clearance ( Ccr ) ) , and the production of
dopamine in the kidney [ uDA/(plasma L - dopa x Ccr ) ] were investigated in
patients with
congestive heart failure ( n = 30 ) and in normal controls ( n = 12 ) . -
pubmed
From these findings , it was suggested that ( i ) uDA was clearly suppressed in
patients with
CHF , and ( ii ) the possible mechanisms of its suppression might be due to decrease of delivery of
L - dopa into the proximal tubules and suppressed production of
dopamine from
L - dopa in the kidney . -
pubmed
Opioids decrease the sympathetic and somatic responses to noxious stimulation and can be given in high doses without negative inotropic effects , even in
patients with
impaired cardiac function . -
pubmed
The duration of action of
remifentanil has been found to be short , even in
patients with
renal or hepatic failure , although only low doses have been used in the studies published to date . -
pubmed
To test for this hypothesis
house rats (
Rattus rattus ) were trapped at a waste disposal site and the levels of micronuclei and
chromosomal aberrations determined . -
pubmed
The results indicate that the frequency of
chromosomal aberrations increases with the weight ( age ) of the animals , while micronuclei did not significantly differ from the level found in laboratory
rats . -
pubmed
We note a less pronounced weight dependent increase of
chromosomal aberrations , most probably reflecting the different residence time at the waste disposal plant , an age dependent decrease of
chromosomal aberrations of the F1 - generation housed in the
animal facility , indicating that the offspring had been exposed transplacentally and an age independent level of chromosomal , aberrations in the F2 - generation not significantly different from that of the Fischer 344 laboratory
rat . -
pubmed
Zinc - bis - histidinate preserves cardiac function in a
porcine model of
cardioplegic arrest . -
pubmed
METHODS : Domestic
pigs ( 35 to 50 kg ) on left - sided cardiopulmonary bypass were subjected to 90 minutes of regional
ischemia followed by 60 minutes of hypothermic cardioplegic arrest induced by antegrade infusion of 20 mL / kg cold St. Thomas ' # 2 cardioplegic solution with or without 100 mumol / L of
zinc - bis - histidinate and maintained by infusion of 10 mL / kg of the same every 20 minutes . -
pubmed
Fulminant
cerebral oedema is an uncommon , fatal complication of
diabetic ketoacidosis (
DKA ) in
children . -
pubmed
OBJECTIVE : To evaluate the ability of
patients with
chronic obstructive pulmonary disease (
COPD ) to accomplish 6 weeks of inspiratory muscle training ( IMT ) using a pressure threshold device , and to observe how the training affected inspiratory muscle strength and
dyspnea . -
pubmed
SUBJECTS : Four
adults with severe
COPD ( the mean of the forced expiratory volume in 1 second [ FEV1 ] was 28 % of predicted value ) . -
pubmed
PURPOSE : ( a ) To compare weight change at 1 year between
adolescents 13 - 19 years old who were using either depot
medroxyprogesterone acetate (
DMPA ) or
oral contraceptives ( OC ) , and ( b ) to determine if age , baseline
body mass index (
BMI ) , race / ethnicity , or
weight gain at 3 months predicted which subjects would gain excessive weight . -
pubmed
When a
patient is being evaluated for posterior
shoulder pain and infraspinatus
muscle weakness , electrodiagnostic studies are an essential part of the evaluation . -
pubmed
The wild
mouse ecotropic retrovirus , Cas - Br - E , induces progressive ,
noninflammatory spongiform neurodegenerative disease in susceptible
mice . -
pubmed
The frequency of three mitochondrial point mutations , 1555A-->G , 3243A-->G , and 7445A-->G , known to be associated with
hearing impairment , was examined using restriction fragment length polymorphism ( RFLP ) analysis in two Japanese groups : ( 1 ) 319 unrelated
SNHL outpatients ( including 21 with
aminoglycoside antibiotic injection history ) , and ( 2 ) 140 cochlear implantation
patients ( including 22 with
aminoglycoside induced
hearing loss ) . -
pubmed
Epoetin alfa therapy effectively ameliorates the
anemia of
end - stage renal disease in pediatric dialysis
patients and thus minimizes many of these negative effects . -
pubmed
Results suggested that
carbaryl ,
esfenvalerate ,
endosulfan , and
deltamethrin had low residual and
acute toxicity to
P. - pubmed
In the endometrium from Norplant
users with
bleeding problems , in vitro supplementation of
vitamin E resulted in a significantly higher angiogenic score than placebo . -
pubmed
Although a highly significant reduction of
bleeding days in both groups ,
vitamin E and placebo , was seen during the 2 months of the study , the number of
bleeding days was significantly lower in
women treated with
vitamin E than with placebo . -
pubmed
However , after inoculation with virulent virus the
pig developed acute fatal
ASF . -
pubmed
The synthesized
nucleosides were assayed against
human immunodeficiency virus ( HIV ) and hepatitis B virus in
human peripheral blood mononuclear ( PBM ) and
2.2.15 cells , respectively . -
pubmed
6 - Amino-9 -[ 2,3 - dideoxy-3 - C -( hydroxymethyl )- 3 - C - methyl - beta - D - glycero - tetrofuranosyl ]- 2 - fluoropurine shows moderate antiviral activity ( EC50 = 2.55 microM ) against
HIV-1 strains and
6 - amino-9 -[ 3 - deoxy-3 - C -( hydroxymethyl )- 3 - methyl - alpha - D - glycero - tetro furanosyl ]- 2 - fluoropurine exhibits potent anti - HIV activity ( EC50 = 0.073 microM ) with significant
cytotoxicity ( IC50 = 1.0 microM ) . -
pubmed
We report a case of
WD with spinal presentation in an otherwise healthy
woman who had a 5 - year history of relapsing - remitting
cervico - thoracic myelopathy . -
pubmed
OBJECTIVE : This study examined the metabolic effects of heart transplantation in
patients in end - stage
cardiac failure . -
pubmed
The
patients were selected from 480 transplant
patients in whom there was a 6 % prevalence of
type 2 diabetes . -
pubmed
There was no significant difference in the 1992 AJCC stages pT2a vs pT2b ( P=0.1232 ) and the
recurrence - free rate was not significantly different for
patients with 1992 AJCC pT3a vs pT3b
disease ( P=0.9 ) . -
pubmed
Patients with infrequent attacks of
supraventricular arrhythmia may benefit from self administration of antiarrhythmic drugs on an ' as required ' basis . -
pubmed
PATIENTS : Nine
newborns ( four
boys , five
girls ) were diagnosed with symptomatic
vein of Galen malformations in the neonatal period during the period 1996 - 2001 . -
pubmed
RESULTS : The immediate outcome after a series of endovascular procedures was control of
cardiac failure and normal neurological function in six ( 66 % )
patients , one
death from intractable
cardiac failure in the neonatal period , and two late
deaths with severe
hypoxic - ischaemic neurological injury ( 33 % mortality ) . -
pubmed
Clinical review at 6 months to 4 years of age showed five
infants with no evidence of
neurological abnormality or
cardiac failure and one
child with mild
developmental delay ( 11 % ) . -
pubmed
Systemic arterial vasodilators improve outcome in
neonates with
cardiac failure secondary to
VGAM . -
pubmed
A 74 - year - old
patient with
hypertension suddenly presented left unilateral
ptosis and
mastication disorders . -
pubmed
Exercise training improves biventricular oxidative metabolism and left ventricular efficiency in
patients with
dilated cardiomyopathy . -
pubmed
OBJECTIVES : The aim of this study was to determine the effect of exercise training on myocardial oxidative metabolism and efficiency in
patients with
idiopathic dilated cardiomyopathy (
DCM ) and mild
heart failure (
HF ) . -
pubmed
BACKGROUND : Exercise training is known to improve exercise tolerance and quality of life in
patients with chronic
HF . -
pubmed
METHODS : Twenty clinically stable
patients with
DCM ( New York Heart Association classes I through III ) were prospectively separated into a training group ( five - month training program ; n = 9 ) and a non - trained control group ( n = 11 ) . -
pubmed
Therefore , exercise training elicits an energetically favorable improvement in myocardial function and exercise tolerance in
patients with
DCM . -
pubmed
The objective of the present study was to compare parameters associated with oxidative phosphorylation and the inner mitochondrial membrane potential of skeletal muscle of
rats submitted to total
ischemia in order to determine which mitochondrial alterations are mainly affected in this condition . -
pubmed
MATERIAL AND METHODS :
Wistar rats were submitted to 5 h total
ischemia using the tourniquet method (
ischemic limb group ) . -
pubmed
CONCLUSIONS : Five - hour total
ischemia applied to
rat skeletal muscle led to the inhibition of the mitochondrial respiratory chain ( represented by decreased state 3 and state 4 respiration rates ) . -
pubmed
PURPOSE : We assessed the effects on spermatogenesis of placebo vs 10 or 20 mg
tadalafil administered daily for 6 months to healthy
men and
men with mild
erectile dysfunction . -
pubmed
MATERIALS AND METHODS : In 2 studies 421 healthy
men or
men with mild
erectile dysfunction who were 45 years or older and met semen criteria derived from WHO reference values were randomized to 6 months of treatment with placebo ( 101 ) or 10 mg
tadalafil ( 103 ) , or to placebo ( 106 ) or 20 mg
tadalafil ( 111 ) . -
pubmed
[ Intravenous virus vaccine confers equal protection in experimental
plague infection induced by three varieties of
Pasteurella pestis ] . -
pubmed
[ Transplantation of the teres major and latissimus dorsi in obstetrical
paralysis of the arm in
children ] . -
pubmed
[ Blood protein picture in
human and experimental
mycoses ] . -
pubmed
Benign paroxysmal positional vertigo in older
women may be related to
osteoporosis and
osteopenia . -
pubmed
Thirty - two
women , whose ages ranged from 50 to 85 years ( median age , 69 years ) , who had
BPPV and were free of any other otoneurologic history , were selected . -
pubmed
The
BPPV was unilateral in 26
patients and bilateral in 6
patients . -
pubmed
Our results showed
osteopenia or
osteoporosis in 24 of the 32
patients ( 75 % ) with
BPPV . -
pubmed
The
patients with
BPPV had a significantly lower ( p & lt ; .026 ) T - score in all groups . -
pubmed
Serosurvey of
viral infections in free - ranging
Namibian cheetahs (
Acinonyx jubatus ) . -
pubmed
Cheetahs (
Acinonyx jubatus ) in captivity have unusually high morbidity and mortality from
infectious diseases , a trait that could be an outcome of population homogeneity or the immunomodulating effects of chronic stress . -
pubmed
To assess the extent to which free - ranging cheetahs are exposed to feline and
canine viruses , sera from 81 free - ranging cheetahs sampled between 1992 and 1998 were evaluated for antibodies against
canine distemper virus (
CDV ) ,
feline coronavirus (
feline infectious peritonitis virus ;
FCoV/
FIPV ) ,
feline herpesvirus 1 (
FHV1 ) ,
feline panleukopenia virus (
FPV ) ,
feline immunodeficiency virus (
FIV ) , and
feline calicivirus (
FCV ) and for
feline leukemia virus (
FeLV ) antigens . -
pubmed
Antibodies against
CDV ,
FCoV /
FIPV ,
FHV1 ,
FPV , and
FCV were detected in 24 , 29 , 12 , 48 , and 65 % of the free - ranging population , respectively , although no evidence of
viral disease was present in any animal at the time of sample collection . -
pubmed
Dietary
aluminium and
renal failure in the
koala (
Phascolarctos cinereus ) . -
pubmed
The study is the first account where
aluminium ingested as part of the natural diet of
mammals has been shown to accumulate in the animal and be implicated with
nephrotoxicity . -
pubmed
Following the initiation of
Metabolife 356 , the
patient experienced four
shocks over a 3 day period with two 30 J
shocks being delivered sequentially . -
pubmed
The aim of the study was to determine whether the cooling process of the
organism in the presence of
ethanol intoxication may be related to inhibition of the physiological mechanism of ketogenesis induced by
hypothermia . -
pubmed
The treatment of
subtrochanteric nonunions with the long gamma nail : twenty - six
patients with a minimum 2 - year follow - up . -
pubmed
A new Coronavirus (
SARS - CoV ) is the aetiological agent of the
severe acute respiratory syndrome (
SARS ) . -
pubmed
Because of the critical role played by serological assays for
SARS diagnosis , an in - house ELISA based on
SARS - CoV recombinant antigens was developed . -
pubmed
Abnormal sperm chromatin condensation is common in sterile men , and our results may provide insight into the molecular mechanisms underlying certain
human infertility disorders . -
pubmed
Seven
patients underwent the procedure -- five with
syringomyelia , one with a symptomatic
perineurial cyst , and one with a large
arachnoid cyst . -
pubmed
Altered diaphragm muscle action potentials in
Zucker diabetic fatty ( ZDF )
rats . -
pubmed
The Zucker diabetic fatty ( ZDF )
rat is a model of
type 2 diabetes , being characterized by
obesity ,
diabetes , and
dyslipidemia . -
pubmed
These findings in ZDF
rats contrast with
type 1 diabetic rats , suggesting that isolated
hyperglycemia differs from
hyperglycemia combined with other metabolic perturbations with respect to diaphragm electrophysiological derangements . -
pubmed
MATERIAL AND METHOD : A total of 63 asymptomatic
patients with
chronic renal failure (
CRF ) with regular hemodialysis were followed for 18 months for cardiac mortality ,
myocardial infarction events and interventional procedures such as percutaneous transluminal coronary angioplasty ( PTCA ) and coronary artery bypass graft ( CABG ) . -
pubmed
Enhanced susceptibility to
arterial thrombosis in a
murine model of
hyperhomocysteinemia . -
pubmed
We tested the hypothesis that
hyperhomocysteinemia accelerates
arterial thrombosis in
mice . -
pubmed
Female
nude mice were subcutaneously implanted with
human gastric cancer cells (
BGC823 ) for the
tumor xenografts studies . -
pubmed
In vivo ,
alphastatin sufficiently suppressed neovascularization of the
tumor in the
nude mice . -
pubmed
Immunohistochemical studies of
tumor tissues revealed decreased micro vessel density in alphastatin - treated
animals as compared with controls . -
pubmed
Enhanced lipid peroxidation and
nitric oxide products with deranged antioxidant status in
patients with
head and neck squamous cell carcinoma . -
pubmed
We conducted a study to evaluate the levels of lipid peroxidation products ,
nitric oxide (
NO ) products and antioxidants in
patients with
head and neck squamous cell carcinoma (
HNSCC ) . -
pubmed
Fifty one
HNSCC patients , 33 healthy
tobacco smokers /
chewers as
tobacco user controls , and 37 non - smokers / chewers as normal controls were recruited for this study . -
pubmed
Lipid peroxidation products , including lipid
hydroperoxide ( LHP ) and
malondialdehyde (
MDA ) ,
nitric oxide (
NO ) products , including
nitrite (
NO ( 2 )(- ) ) ,
nitrate (
NO ( 3 )(- ) ) , and total
nitrite (
TNO ( 2 )(- ) ) were found to be significantly elevated with a concomitant depletion of antioxidants in
HNSCC patients as compared to
tobacco users and normal controls . -
pubmed
Prognostic implications of preoperative
atrial fibrillation in
patients undergoing aortic valve replacement : is there an argument for concomitant
arrhythmia surgery ? -
pubmed
RESULTS :
Patients with preoperative
AF presented with more severe
congestive heart failure ( p = 0.03 ) and more often had significant
tricuspid regurgitation ( p = 0.01 ) preoperatively . -
pubmed
They also had worse late survival ( risk ratio [ RR ] for
death = 1.5 , p = 0.03 ) with 1- , 5- , and 7 - year survival rates substantially reduced at 94 % , 87 % , and 50 % , respectively , for those in
AF versus 98 % , 90 % , and 61 % for
patients in sinus rhythm preoperatively . -
pubmed
Individuals in
AF had a greater probability of subsequent rhythm - related intervention ( RR = 4.7 , p = 0.0002 ) , and more frequently developed
congestive heart failure ( 25 % vs 10 % , p = 0.005 ) and
stroke ( 16 % vs 5 % , p = 0.005 ) . -
pubmed
CONCLUSIONS : Performance of concomitant
arrhythmia surgery in
patients undergoing aortic valve surgery may reduce late morbidity ; however , its potential impact on late mortality in this high - risk subset of
patients remains unclear . -
pubmed
We therefore aimed in this study to investigate the effect of
ID on BAEPs by comparing three groups of
infants with
ID ,
IDA and
iron sufficiency ( control ) both before and after
iron treatment ( in
iron - deficient groups ) . -
pubmed
To identify such targets , we screened cDNA libraries from
human testis , lung and
breast cancer ,
bovine and
porcine muscle and
wheat germ for reactivity with paraproteins in the sera from 115
patients with
MGUS and
MM . -
pubmed
The broad spectrum of auto- , allo- and heteroantigens as targets of
human paraproteins in
patients without signs of chronic antigenic stimulation renders a causal role of the antigenic stimulus in the pathogenesis of
MGUS and
MM unlikely . -
pubmed
Measurements were made in normal
rats and in
rats with
arthritis induced in one knee by intraarticular injections of kaolin / carrageenan . -
pubmed
Studies on
Leptospira Infection in Rodents and
Dogs in Columbia . -
pubmed
There was evidence of decreasing prevalence of
IPNV in mussels from Shetland once IPN outbreaks subsided , indicating they are an unlikely source of
re - infection on farms . -
pubmed
FINDINGS : The number of irreversible heel pressure
ulcers was lower in the experimental ( 3
patients , 8.6 % ) than in the control group ( 19 patients , 55.4 % ) ( p<0.0001 ) . -
pubmed
CONCLUSION : An anatomical foam body - support is effective in preventing heel pressure
ulcers in
patients on a medical intensive care unit and is well tolerated . -
pubmed
[ Systemic
inflammation and experimental
cancer in a
murine model ] . -
pubmed
The link between
cancer and
inflammation in an organ or tissue has firmly been established on the basis that
cancer tends to occur at sites of chronic
inflammation and that local inflammatory processes can accelerate the growth of preexisting
tumors in both animals and
human beings . -
pubmed
In
mice bearing a large
MC - C tumor , a high number of circulating PMN and myeloid precursors were evident . -
pubmed
Microvascular ear reconstruction using a free radial forearm flap after
dog bite . -
pubmed
A 68 - year old
woman suffered from a subtotal amputation of the left ear due to a
dog bite . -
pubmed
Twelve hours after the last injection , the
animals were sacrificed by
decapitation without anaesthesia . -
pubmed
Effect of temperature on heart rate in diploid and
triploid brook charr ,
Salvelinus fontinalis , embryos and larvae . -
pubmed
The aim of this study was to determine whether heart rate differs between
triploid and control ( diploid )
brook charr ,
Salvelinus fontinalis , at embryo - larval stages , when the heart is easily visible and the fish are relatively inactive . -
pubmed
A
herring gull neuronal cell culture method was used to determine the effects of
PBDEs on
cytotoxicity and mRNA expression . -
pubmed
Patients with
TACs often visit dental offices seeking relief for their
pain . -
pubmed
High prevalence and early complication of symptomatic
vertebral fracture in elderly
people treated with high - dose glucocorticoids . -
pubmed
Hashimoto described four
patients with
goiter . -
pubmed
Hypothyroid patients with
Hashimoto ' s thyroiditis usually receive life - long
l - thyroxine therapy . -
pubmed
Patients who had
Hashimoto ' s hypothyroidism and then
Graves ' hyperthyroidism ( and vice versa ) , have also been reported . -
pubmed
METHODS :
Colitis was induced by
trinitrobenzene sulfonic acid and
ethanol in 30
rats under general anesthesia , and 10
rats were used as a sham group . -
pubmed
Subsequent to induction of
colitis ,
rats were divided into three groups ;
budesonide group received 0.1 mg / kg
budesonide ,
levobupivacaine group received 10 mg / kg
levobupivacaine and saline group received 1 mL saline solution via rectal route for 7 d. In the sham group , only routine rectal catheterization was performed without use of any material . -
pubmed
Antimitotic agents such as
taxanes (
paclitaxel and
docetaxel ) have greatly advanced the treatment of
breast cancer , although variable
patient response and
drug toxicity are major limitations . -
pubmed
However , mechanisms of
curcumin - inhibited cell growth and -induced apoptosis in
human non -
small cell lung cancer cells (
NCI - H460 ) still remain unclear . -
pubmed
One
patient ( 4.3 % ) underwent secondary fusion surgery due to persistent
pain . -
pubmed
Population pharmacokinetics of
ustekinumab in
patients with active
psoriatic arthritis . -
pubmed
Patient body weight and antibody - to -
ustekinumab status were significant covariates affecting the CL / F and/or V / F of
ustekinumab . -
pubmed
CONCLUSION : The pharmacokinetics of
ustekinumab in
patients with
PsA are comparable to those in
patients with moderate - to - severe
plaque psoriasis which was previously investigated . -
pubmed
For example , a reduced ability to masticate , such as that resulting from toothlessness or soft - diet feeding , causes
learning and memory deficits in aged
animals and pathologic changes in the hippocampus . -
pubmed
Improved outcome after anesthesia with volatile anesthetics in non - cardiac surgical
patients at risk of perioperative
myocardial infarction has not been univocally demonstrated yet . -
pubmed
METHODS :
Human endothelial cell monolayers (
human umbilical vein endothelial cells (
HUVECs ) and
human microvascular endothelial cells of the lung (
HMEC-1s ) ) were exposed to ROS production , after which electrical impedance , cellular integrity and
tumour cell adhesion were investigated . -
pubmed
Treatment of
rats with the ROS scavenger
edaravone prevented surgery - induced
tumour cell adhesion and downregulation of tight junction proteins in the liver . -
pubmed
In light of this , perioperative therapeutic intervention , preventing surgery - induced inflammatory reactions , may reduce the risk of developing
liver metastases , thereby improving the clinical outcome of
patients with
colorectal cancer . -
pubmed
OBJECTIVE :
Septic shock heterogeneity has important implications for clinical trial implementation and
patient management . -
pubmed
Glioblastoma (
GBM ) , the most common primary
brain tumor in
adults , is one of the most aggressive
human cancers associated with high mortality . -
pubmed
However , almost all
patients develop
disease progression following this multimodal therapy . -
pubmed
We investigated the effects of
Fascioloides magna infection on the serum biochemistry values of the naturally infected
red deer population in eastern Croatia . -
pubmed
Further investigation of changes in liver enzymes and other serum metabolites in controlled , experimentally induced
fascioloidosis in
red deer is needed to better understand the pathogenesis of
F. - pubmed
This product be used as a biodrug in maintaining the blood
glucose level in
diabetic patients . -
pubmed
Compared with participants with a normal
body mass index ( & lt;25 kg / m(2 ) ) ,
obese women ( & gt;=30 kg / m(2 ) ) had a
25 -( OH ) D level that was 17.8 nmol / L lower . -
pubmed
Enterotoxigenic
Escherichia coli (
ETEC ) is a major cause of
diarrhoea in neonatal and postweaning pigs . -
pubmed
F41 is one of
ETEC fimbriae that adhere to the small intestinal epithelium and lead to development of
diarrhoea . -
pubmed
Patients waking up with
stroke symptoms are generally excluded from intravenous thrombolysis . -
pubmed
If positive the WAKE - UP trial is expected to change clinical practice and to make effective and safe treatment available for a large group of
acute stroke patients currently excluded from specific acute treatment . -
pubmed
No significant differences were found when comparing impairment ,
pain ,
patient satisfaction and disability . -
pubmed
Allergy to
citrus fruits is often associated with
pollinosis and sensitization to other plants due to a phenomenon of cross - reactivity . -
pubmed
The aims of the present study were to highlight the cross - reactivity among
citrus and the major allergenic pollens / fruits , throughout clinical and molecular investigations , and to evaluate the sensitization frequency to
citrus fruits in a population of children and adults with
pollinosis . -
pubmed
Neospora caninum is an important intracellular protozoan parasite with an affinity to the central nervous system of many animals and a major causative agent of
repeated abortions in
cattle . -
pubmed
Further studies are needed with
123I - mIBG to assess its utility in
patients with early
cardiac autonomic neuropathy . -
pubmed
The prevalence of any
helminthic infection ,
Ascaris lumbricoides ,
Trichuris trichiura , and
hookworm were 25.0 % , 18.2 % , 9.2 % , and 5.3 % , respectively . -
pubmed
Hypertensive women , affected by APA , present urinary SB3 concentrations significantly higher than
women affected by
BAH . -
pubmed
A 24 - year - old
man was diagnosed with
klinefelter ' s syndrome (
KS ) and his wife was found to have an inversion on chromosome 9 - 46 , XX , inv ( 9 ) ( p11q21)- because of
infertility . -
pubmed
Desmopressin orally disintegrating tablet in Japanese
patients with
central diabetes insipidus : a retrospective study of switching from intranasal
desmopressin . -
pubmed
Patients with
CDI have been successfully treated with
desmopressin administered either by intranasal instillation or oral tablets . -
pubmed
We conducted a retrospective single - center study of 15
Japanese CDI patients treated with
desmopressin ODT therapy , which aimed to evaluate the efficacy and safety of switching to
desmopressin ODT and to analyze the clinical factors that affect the
desmopressin ODT dose in Japanese
patients . -
pubmed
In conclusion ,
desmopressin ODT was safe and effective in the treatment of Japanese adult
CDI patients . -
pubmed
Correlation between
Microalbuminuria and
Hypertension in
Type 2 Diabetic Patients . -
pubmed
BACKGROUND :
Hypertension is commonly found in
patients with
Diabetic Kidney Disease (
DKD ) . -
pubmed
Microalbuminuria is the first clinical sign of involvement of kidneys in
patients with
type 2 diabetes . -
pubmed
OBJECTIVES : To determine the correlation between
microalbuminuria and
hypertension and their association with other risk factors in
type 2 diabetic patients . -
pubmed
METHODS : One hundred and thirteen
type 2 diabetic patients attending the
diabetic clinic of Shaikh Zayed Postgraduate Medical Institute , Lahore , Pakistan were screened for
microalbuminuria and raised blood pressure . -
pubmed
Group 2
patients showed
higher blood pressure values as compared to Group 1 . -
pubmed
So , early recognition of
renal dysfunction through detection of
microalbuminuria and to start treatment without any delay will confer future protection from
end stage renal disease as well as
hypertension and its complications in
type 2 diabetic patients . -
pubmed
Many of these were acute - phase response proteins , previously reported to be increased in
depressed patients . -
pubmed
High intake of staples , especially
rice , was positively associated with
endometrial cancer . -
pubmed
BACKGROUND : Based on results of the PLATO ( Platelet Inhibition and
Patient Outcomes ) trial comparing
ticagrelor with
clopidogrel therapy , the U.S. Food and Drug Administration approved
ticagrelor in 2011 for reducing
thrombotic cardiovascular events in
patients with
acute coronary syndrome (
ACS ) with the proviso that it be taken with low - dose
aspirin . -
pubmed
The aim of the study was to assess the quality of life amongst
patients with morbid
obesity as well as the impact of bariatric treatment on
body weight and
obesity - related diseases in addition to conducting an analysis of changes in the quality of life after surgical treatments , in the context of the surgical procedure type and degree of body
weight loss . -
pubmed
MATERIAL AND METHODS : Sixty - five
patients were treated for morbid
obesity . -
pubmed
Women during the third trimester of pregnancy and
children at ages 3 and 5 years provided
spot urine samples . -
pubmed
The recent clinical success of immunotherapy in the treatment of certain types of
cancer has demonstrated the powerful ability of the immune system to control
tumor growth , leading to significantly improved
patient survival . -
pubmed
Clinical data of examined
patients and imaging findings in terms of description of the hepatic parenchyma and the presence of
BFLL , were recorded . -
pubmed
The
mice were treated with QL for three days before surgery and continually after I / R.
Triphenyltetrazolium chloride staining , echocardiography and Masson 's trichrome staining were used to determine
infarct size , cardiac function , and
fibrosis , respectively . -
pubmed
RESULTS : At 1 day after I / R , QL treatment significantly reduced the
infarct size of
mice exposed to I / R. At 7 days after I / R , mortality was reduced in QL treated
animals in comparison with the control group . -
pubmed
In addition , QL treated
mice showed increased left ventricular ejection fraction ( LVEF ) and left ventricular fractional shortening ( LVFS ) at 1 and 7 days after I / R. In agreement , Masson 's trichrome staining demonstrated that interstitial
fibrosis was less pronounced in QL treated
mice compared with controls , suggesting that adverse left
ventricular remodeling is attenuated in QL treated
mice . -
pubmed
In vivo antitumor study also substantiated the dramatically enhanced efficacy of
DTX /
Ac - betaCD NPs in a
melanoma - bearing
nude mouse model . -
pubmed
We found robust sprouting of uninjured corticospinal and serotonergic fibers in a
rat cervical hemisection
SCI model . -
pubmed
A
mouse pyramidotomy model was used to confirm that this robust sprouting was not species or
injury model specific . -
pubmed
We found robust sprouting of uninjured corticospinal and serotonergic fibers in a
rat hemisection
spinal cord injury model . -
pubmed
Long - term benefit of liposuction in
patients with
lipoedema : a follow - up study after an average of 4 and 8 years . -
pubmed
BACKGROUND : Long - term results following liposuction in
patients with
lipoedema are available only for an average period of 4 years . -
pubmed
METHODS : In a single - centre study , 85
patients with
lipoedema had already been examined after 4 years . -
pubmed
CONCLUSION : These results demonstrate for the first time the long - lasting positive effects of liposuction in
patients with
lipoedema . -
pubmed
METHODS : A retrospective review of
children aged up to 17 years who had surgery for
intussusception at this institution between 1 January 2004 and 31 December 2013 . -
pubmed
RESULTS : The cohort of 44
individuals ( 18
females ) presented at a median age of 9 months ( range 2.5 months-15.75 years ) with
intussusception ; 36
patients had undergone a failed pneumatic reduction . -
pubmed
Conversion was required in 13
individuals : inability to reduce a ' tight '
intussusception in seven individuals , limited working space in four individuals , and inadequate tactile response in two individuals . -
pubmed
An open approach was chosen for seven
individuals at a median age of 5 ( range 4 - 11 ) months : three individuals had marked
abdominal distension , two individuals had a
pneumoperitoneum and two individuals presented with a large central mass . -
pubmed
Methods The study included 50
bladder cancer patients , 50 with
urinary tract infection and 51 healthy
volunteers . -
pubmed
This parameter also increases in serum and urine of
cases with
urinary tract infection . -
pubmed
This article describes a
patient with atraumatic multifocal intracerebral , subarachnoid , and bilateral frontal convexity
acute subdural hematomas . -
pubmed
The patient is a 46 - year - old Caucasian
man who presented with a spontaneous severe progressive
headache . -
pubmed
Felis catus papillomavirus type 2 (
FcaPV2 ) DNA is found in
feline cutaneous squamous cell carcinomas (
SCCs ) ; however , its biological properties are still uncharacterized . -
pubmed
Clinical phtorejuvenation effect was also evaluated from nine
patients who had PDT to treat
actinic keratoses . -
pubmed
BACKGROUND :
Porcine wounds closely mimic
human wounds and are often used experimentally in
burn studies . -
pubmed
The
burn injury was inflicted by preheating the
burn device to 100 C and pressing on the dorsum of
pig skin for different time points ranging from 5 to 30s using standardized force of 10N on the device . -
pubmed
CONCLUSION : The authors describe a simple , standardized and reproducible
animal burn model using a customized
burn device . -
pubmed
A study of the free radical scavenging effects of
Piper betle leaf extract in
patients with
vitiligo . -
pubmed
METHODS : The effect of
Piper betle on the generation of reactive
oxygen species in erythrocytes was measured by flow cytometry in
patients with active and stable
vitiligo versus healthy controls , using
5 -( and-6 )- chloromethyl-2 '- 7 '- dichlorodihydrofluorescein diacetate . -
pubmed
RESULTS : The generation of reactive
oxygen species in erythrocytes was higher in
patients with
vitiligo ( n = 23 ) compared to healthy controls ( n = 18 ) . -
pubmed
The levels of reactive
oxygen species were higher in
patients with active
vitiligo . -
pubmed
Treatment of erythrocytes with
Piper betle in concentrations of 0.5 and 1.0 mug / ml significantly decreased the baseline levels of reactive
oxygen species by 31.7 % in healthy controls , and 47.6 % and 44.3 % in
patients with active
vitiligo , respectively . -
pubmed
Piper betle effectively scavenged
hydrogen peroxide , which was evident by a decrease in the geometrical mean fluorescence channel by 52.4 % and 62.9 % in healthy controls , and 45.0 % and 57.0 % in
patients with active
vitiligo . -
pubmed
CONCLUSION : This pilot study indicates that
patients with active
vitiligo demonstrate enhanced generation of reactive
oxygen species in erythrocytes , which was significantly reduced following ex vivo treatment with
Piper betle . -
pubmed
While the total amount of left - atrial adipose tissue was higher in the
sheep with
AF , no changes in regional coverage were observed . -
pubmed
Objectives : The aims were to assess the prevalence of
malnutrition and to validate bioelectrical impedance analysis ( BIA ) against whole - body DXA for the assessment of body composition in
patients with
SSc . -
pubmed
Fiber - rich diet with
brown rice improves endothelial function in
type 2 diabetes mellitus : A randomized controlled trial . -
pubmed
We hypothesized that a fiber - rich diet with
brown rice improves endothelial function in
patients with
type 2 diabetes mellitus . -
pubmed
METHODS : Twenty - eight
patients with
type 2 diabetes mellitus at a single general hospital in Japan were randomly assigned to a brown
rice ( n = 14 ) or white
rice ( n = 14 ) diet and were followed for 8 weeks . -
pubmed
The results of the bacteria ( BAC ) and
yeast ( YEA ) analyses were compared with the results from urine culture as a method for
UTI screening . -
pubmed
The study aimed to establish the fungicidal , efficacy and safety profile of Calmagen dermaceutical cream and lotion containing AMYCOT as a topical treatment in
patients with severe to very severe presentations of fungal skin (
tinea ) and
nail infections (
onychomycosis ) . -
pubmed
METHODS : A randomized , placebo - controlled , double blind , parallel , single centre study was conducted on 28
subjects with severe to very severe
tinea or
onychomycosis . -
pubmed
Uveitis activity improved in 22 eyes of 15
patients ( 13 treated adequately for active
TB , 2 not adequately treated ) . -
pubmed
All 9
individuals presenting with
posterior or panuveitis who improved were adequately treated whereas the remaining 2 who did not improve were not ( P 0.02 ) . -
pubmed
Apnea induction for invasive lung function testing in
infant olive baboons : Comparison of intravenous
propofol versus
hyperventilation . -
pubmed
We compared two methods of
apnea induction in infant
olive baboons (
Papio anubis ) . -
pubmed
CONCLUSIONS : Intravenous
propofol was non - inferior to
CO2 washout for
apnea induction in infant
olive baboons . -
pubmed
Perinatal
Bisphenol A Exposure Induces Chronic
Inflammation in
Rabbit Offspring via Modulation of Gut Bacteria and Their Metabolites . -
pubmed
In this report , we show how perinatal
BPA exposure in
rabbits alters gut microbiota and their metabolite profiles , which leads to
colonic and liver inflammation as well as to increased gut permeability as measured by elevated serum lipopolysaccharide ( LPS ) levels in the offspring . -
pubmed
Also , perinatal
BPA exposure leads to reduced levels of gut
bacterial diversity and
bacterial metabolites (
short - chain fatty acids [
SCFA ] ) and elevated gut permeability - three common early biomarkers of
inflammation - promoted
chronic diseases . -
pubmed
MATERIALS AND METHODS : Twenty - nine
patients with
amyotrophic lateral sclerosis and 22 healthy controls were scanned with 3 T MR imaging . -
pubmed
A statistical analysis assessed the difference in cross - sectional areas between
patients with
amyotrophic lateral sclerosis and controls , correlations between spinal cord and gray matter
atrophy to clinical disability at baseline and at 1 year , and prediction of clinical disability at 1 year . -
pubmed
RESULTS : Gray matter
atrophy was more sensitive to discriminate
patients with
amyotrophic lateral sclerosis from controls ( P = .004 ) compared with
spinal cord atrophy ( P = .02 ) . -
pubmed
We describe the use of a cognitive trainings app by a young
woman with highly resistant
hallucinations . -
pubmed
Phenotypic and genotypic characterization of antimicrobial resistance profiles in
Streptococcus dysgalactiae isolated from bovine clinical
mastitis in 5 provinces of China . -
pubmed
Bovine
mastitis is among the most prevalent and costly diseases of dairy animals and is caused by a variety of bacterial pathogens including
Streptococcus dysgalactiae . -
pubmed
In total , 1,180 milk samples were collected from dairy
cows with clinical
mastitis belonging to 74 commercial dairy herds located in 14 provinces of China from January 2014 to May 2016 . -
pubmed
Setting : HIV /
AIDS Cancer Match Study to project
cancer rates and
HIV Optimization and Prevention Economics model to project HIV prevalence . -
pubmed
Chronic
iron overload induces
vascular dysfunction in resistance pulmonary arteries associated with right ventricular remodeling in
rats . -
pubmed
Moreover ,
rats treated with the highest dose exhibited
RV dysfunction and
hypertrophy ; inward remodeling and increased vasoconstriction of the RPA . -
pubmed
The
olive knot disease (
Olea europea L. ) is caused by the bacterium
Pseudomonas savastanoi pv . - pubmed
Decreased cerebral blood flow and improved cognitive function in
patients with
end - stage renal disease after peritoneal dialysis : An arterial spin - labelling study . -
pubmed
METHODS :
ESRD patients undergoing PD were recruited . -
pubmed
Age- and sex - matched normal
subjects without
ESRD served as the control group . -
pubmed
RESULTS :
ESRD patients showed poor performance in many of the neuropsychological tests ; PD improved cognition in some domains . -
pubmed
CONCLUSION : Before
PD ,
ESRD patients had increased cerebral perfusion that was related to poorer executive function , especially in the left hippocampus . -
pubmed
KEY POINTS : In this study ,
ESRD patients before
PD had
cerebral hyperperfusion that was related to poorer executive function . -
pubmed
The degree of
anaemia might predict
cognitive impairment in
PD patients . -
pubmed
Seizures ,
status epilepticus , and
seizure - like rhythmic or periodic activities are common , pathological , harmful states of brain electrical activity seen in the electroencephalogram ( EEG ) of
patients during critical medical illnesses or
acute brain injury . -
pubmed
177Lu - DOTA - HYNIC - Lys ( Nal )- Urea - Glu : Biokinetics , Dosimetry , and Evaluation in
Patients with Advanced
Prostate Cancer . -
pubmed
177Lu - iPSMA obtained from kit formulations showed high
tumor uptake with good response rates in
patients . -
pubmed
[ A screening algorithm for
patients with
adrenal incidentalomas ] . -
pubmed
Integrated clinical and economic analysis of the efficiency of screening was made in
patients with
adrenal incidentalomas under the established practical conditions ; the average cost of screening of a
patient with
adrenal incidentalomas and the cost of one detected case were determined under these conditions . -
pubmed
Based on the clinical and economic analysis , the authors have elaborated and scientifically substantiated an algorithm for screening of
patients with
adrenal incidentalomas , the use of which will permit , with high clinical efficacy , a significant reduction in the cost of screening . -
pubmed
This work measured the hazardous nature of 100 nm
micropolystyrene ( MPS ) using 25 , 50 , 100 , 200 , and 400 mg / L concentrations in terms of oxidative stress , morphotoxicity and
cytogenotoxicity in
Allium cepa . -
pubmed
The current study examined whether the precision medicine approach was able to identify specific
individuals with
BPSD who could benefit from
benzoate treatment . -
pubmed
Methods : In the randomized , double - blind , placebo - controlled , 6 - week trial , 97
patients with
BPSD were allocated to receive 250 - 1500 mg / day of
sodium benzoate or placebo . -
pubmed
Conclusion : The finding suggests that
sodium benzoate may have potential to benefit cognitive function in a fraction of
BPSD patients after 6 weeks of treatment . -
pubmed
The proposed approach was validated on data obtained from 12
patients with
AS . -
pubmed
Effect of cryotherapy on
arteriovenous fistula puncture - related
pain in hemodialysis
patients : A systematic review and meta - analysis . -
pubmed
BACKGROUND AND PURPOSE :
Patients undergoing continuous hemodialysis experience the
arteriovenous fistula puncture - related
pain approximately 300 times per year . -
pubmed
Therefore , this systematic review and meta - analysis study was conducted to determine the effect of cryotherapy on
arteriovenous fistula puncture - related
pain in hemodialysis
patients . -
pubmed
The review of studies showed a positive effect of cryotherapy on reducing the
arteriovenous fistula puncture - related
pain in hemodialysis
patients . -
pubmed
Retinoblastoma (
RB ) is one of the most common primary
intraocular malignancies in
children . -
pubmed
Consistently , the higher expression levels of miR-424 were closely associated with the poor clinical outcome of the
bladder cancer patients . -
pubmed
To summarize the distribution of
glioma location within a
patient population , registration of individual MR images to anatomical reference space is required . -
pubmed
Objective : To compare the clinical and imaging characteristics of
patients with stage I coal worker 's
pneumoconiosis (
CWP ) . -
pubmed
We performed a systematic review and meta - analysis to evaluate the efficacy of probiotics in improving
gastrointestinal ( GI ) symptoms and quality of life ( QOL ) in
patients with
CD . -
pubmed
DISCUSSION : Probiotics may improve GI symptoms in
patients with
CD . -
pubmed
To assess the accuracy of the mammary volume - to -
body mass index ( MV -
BMI ) ratio as an indicator of
cardiovascular disease (
CVD ) risk in morbidly obese
patients and as a preoperative predictor of long - term outcomes after SG . -
pubmed
RESULTS : Thirty - two
patients with
CNLDO were included . -
pubmed
Gram - positive bacteria accounted for 60.5 % of all the
strains , with
Streptococcus ( 50 % ) being the most frequent species , whereas Haemophilus ( 21.1 % ) and Neisseriae ( 13.2 % ) were most common isolates for Gram - negative organisms . -
pubmed
CONCLUSIONS : Infants with
CNLDO under 1 year of age presented predominance of
Streptococcus as Gram - positive organism , and Haemophilus as Gram - negative organism . -
pubmed
PET imaging assessed the localization of
89Zr - REGN3504 to multiple
human tumor xenografts . -
pubmed
RESULTS : Clear localization of
89Zr - REGN3504 to
human tumor xenografts was observed via PET imaging and ex vivo biodistribution studies demonstrated high ( fourfold to sixfold )
tumor : blood ratios . -
pubmed
Serial
bleedings were obtained from two mules during prolonged immunization , one with type XXV the other with type VIII
pneumococcal vaccine . -
pubmed
Thus , until a superior regimen is established , I recommend local and regional irradiation for
patients at high risk for
recurrence . -
pubmed
Thirty - nine
patients with
small cell lung cancer were treated with large dose intravenous
cyclophosphamide combined with
vincristine . -
pubmed
Perinatal hypothyroidism in
rats : persistent motivational and metabolic effects . -
pubmed
These
rats also showed
hyperactivity in asymptotic running - wheel performance , increased spontaneous recovery of extinguished lever - pressing , and elevated responding in lever - pressing for variable - interval food reinforcement . -
pubmed
In general the results indicate that perinatal
thyroid deficiency engenders a chronic hypermetabolic state in both sexes which may be associated with a persistent , mild
hyperthyroid condition in the case of female
rats . -
pubmed
The p locus is closely linked to the
mouse homolog of a gene from the
Prader - Willi chromosomal region . -
pubmed
Renal hypertrophy and hyperfiltration are early manifestations of
human and experimental
diabetes that may contribute to the late development of
diabetic nephropathy . -
pubmed
Since growth of various tissues is accompanied by increased formation of
polyamines , we studied whether
polyamines were involved in the growth of the kidney observed in
diabetic rats . -
pubmed
[ The influence of soft tissue
contractures on the walking ability of
patients with
spastic cerebral palsy ] . -
pubmed
The influence of soft tissue
contractures on walking ability was investigated in 73
patients with
spastic cerebral palsy . -
pubmed
Currently , there is
confusion in the literature regarding appropriate treatment of
patients known to possess these antibodies . -
pubmed
We have reported the case of a
patient at 29 weeks ' gestation who had elevated blood pressure ,
proteinuria , and early
intrauterine growth retardation . -
pubmed
After delivery ,
chest pain and a
pleural effusion developed as further manifestations of the
patient 's
autoimmune disease . -
pubmed
An 65 - year - old
woman sustained
respiratory distress after coronary artery bypass grafting because of bilateral phrenic nerve
paralysis . -
pubmed
We believe that surgical plication of the diaphragm is a safe and effective technique for a distressed adult
patient with
paralyzed diaphragm . -
pubmed
Double - blind placebo - controlled study of
nortriptyline in
depressed adolescents using a " fixed plasma level " design . -
pubmed
All three
men with the deficiency had severe , chronic , bilateral , lower extremity ,
venous insufficiency manifested by
pain ,
varicosities ,
edema ,
pigmentation , and
ulceration . -
pubmed
The
calves were assigned to four treatment groups balanced according to
body weight . -
pubmed
Calves fed the low P ( deficient ) diet showed significant reductions in feed intake ,
weight gain , serum inorganic P , bone ash , and P content of bone . -
pubmed
Twenty - nine
patients with
stage III testicular tumours seen between 1979 and 1984 were analysed for the relation between delay in both diagnosis and chemotherapy , and prognosis . -
pubmed
Biochemical characteristics of
mouse mammary tissues ,
preneoplastic lesions and
tumors . -
pubmed
A number of metabolizing systems are measured in normal , preneoplastic and
neoplastic mouse mammary tissues derived under three different conditions . -
pubmed
Role of
thiol agents in protecting against the
toxicity of
helenalin in
tumor - bearing
mice . -
pubmed
Helanalin , a
sesquiterpene lactone antineoplastic agent , is toxic at therapeutic doses in
murine tumors . -
pubmed
with
L - cysteine ( 100 mg / kg / day ) ,
beta - mercaptoethanolamine ( 20 mg / kg / day ) ,
18 - beta - glycyrrhetinic acid ( 15 mg / kg / day ) , or
4,4 '- diaminodiphenylsulfone ( 10 mg / kg / day ) afforded improvement in survival of
mice bearing P-388
lymphocytic leukemia . -
pubmed
Antibody titers were significantly higher in
patients with an intraventricular vesicle or
cyst . -
pubmed
A 10 year - old
girl presented with a progressive left
ureteral colic with
abdominal tenderness . -
pubmed
Serum antibody does not account for differences in the severity of chronic
respiratory disease caused by
Mycoplasma pulmonis in LEW and
F344 rats . -
pubmed
Chronic
respiratory disease in
rats , resulting from
Mycoplasma pulmonis infection , is useful in the study of the immunological mechanisms in similar
inflammatory diseases and provides a unique opportunity to study the interactions between systemic and mucosal immune systems in a naturally occurring
infection . -
pubmed
pulmonis in
strains of
rats which differ in
disease progression and severity ;
LEW rats developed more severe disease than did
F344 rats . -
pubmed
pulmonis antigens than did
F344 rats , and there was no difference in the antigens eventually recognized by each
strain , confirming previous work which suggested that LEW
rats do not exhibit an unresponsiveness to a specific antigen(s ) of
M. - pubmed
Computerized tomography was positive for
pituitary tumour in three
patients . -
pubmed
Reproducibility of ventilatory measurements during sleep on different nights in
patients with
chronic obstructive pulmonary disease . -
pubmed
To evaluate the reproducibility of respiratory measurements between nights we performed studies in 20
outpatients with stable , moderately severe
chronic obstructive pulmonary disease . -
pubmed
All
patients had symptoms from their
lung disease but had no sleep complaints . -
pubmed
Urinary tract infections in
patients undergoing transurethral prostatectomy . -
pubmed
The incidence of
urinary tract infections was determined in 1,660
patients undergoing transurethral prostatectomy . -
pubmed
Preoperative
infection was found in 25 % of all
patients and in 35 % of the 276
patients aged 80 years or over . -
pubmed
Of the 1,251
patients without a preoperative
infection , 17 % had
postoperative infections . -
pubmed
This report describes a
patient with severe
subaortic stenosis ,
patent ductus arteriosus , and mild
pulmonary branch stenosis , a rare condition . -
pubmed
A 6 3/4 - year - old
boy with neuronopathic
Gaucher ' s disease died unexpectedly . -
pubmed
After 575 renal transplantations with 147 angiographies
arterial stenoses were observed in nine
patients ( 1,6 % ) and corrected surgically . -
pubmed
Attempts to close a median sternotomy incision in the
patient with profound
cardiac or pulmonary dysfunction following a cardiac surgical procedure can result in severe hemodynamic deterioration . -
pubmed
[ Preliminary studies of
porcine piroplasmosis in the northern Ivory Coast . -
pubmed
Antibody studies of sera from
patients with
breast cancer . -
pubmed
Metabolic and heart rate response of the plethodontid salamander
Desmognathus fuscus to
hypoxia . -
pubmed
Relapse mechanisms in
malaria : emergence of variant
strains of
Plasmodium lophurae from serum antigen - immunized ducks . -
pubmed
Patient is now alive 3 years posttherapy with a functional vagina , return of menses , and without evidence of
tumor . -
pubmed
[ Structuro - functional transformation of the microcirculatory bed of the lungs in
children with chronic nonspecific
inflammation of the lungs ] . -
pubmed
Considerable morphological alterations in the capillary network found in
patients with a coarse deforming
bronchitis confirmed the reasons for the surgical treatment of such patients . -
pubmed
Differentiation of
human myeloid leukemic cells by
phorbol esters : correlation with
tumor promotion . -
pubmed
Similar results were obtained in 3 different established cell lines , as well as in short - term cultures of cells obtained from
patients with
acute myeloid leukemia . -
pubmed
Clinical and urodynamic examinations were carried out in 63
patients with
Parkinson ' s disease presenting with
disorders of the urinary bladder sphincters with no detectable other neurological or urological cause . -
pubmed
[ Interrelation of the functional activity of leukocytes in the bronchial secretion and peripheral blood of
patients with
nonspecific lung diseases ] . -
pubmed
[ Development of
lymphoma and
leukemia in
patients receiving immunosuppressive drugs ] . -
pubmed
Seventy - five
strains of
Clostridium difficile were recovered from 1,276 stools from patients . -
pubmed
For this reason , we tested serum samples from patients with
typhoid fever ,
brucellosis ,
toxoplasmosis ,
amoebiasis ,
cysticercosis ,
trichocephaliasis ,
ascariasis , and
onchocerciasis against an antigenic extract of
T. - pubmed
A
patient with
Terrien ' s corneal marginal degeneration and a previous trabeculectomy had planned extracapsular
cataract extraction with intraocular lens implantation . -
pubmed
Bone turnover in
asthmatic children treated with oral
prednisolone or inhaled
budesonide . -
pubmed
Biochemical markers of bone turnover were studied in prepubertal
school children with
asthma in two randomized double - blind crossover trials with run - in , treatment , and wash - out periods of 2 weeks . -
pubmed
Short - term treatment with low daily doses of
prednisolone may cause a
suppression of bone turnover in
children with
asthma . -
pubmed
Choreoathetosis developed in three
patients after cardiopulmonary bypass with
hypothermia . -
pubmed
The infusion of anti - RhO-(D ) opsonized erythrocytes may be useful in the treatment of
patients , splenectomized or not , with chronic , refractory
autoimmune thrombocytopenic purpura -- a prospective study . -
pubmed
Ten
patients with extensive
plaque psoriasis were treated with
calcipotriol ointment ( 50 micrograms / g ) for 2 weeks ( 200 g for 1 week , followed by 300 g during the second week ) . -
pubmed
Topical
calcipotriol is an effective , rapidly acting and safe in -
patient treatment for extensive
plaque psoriasis . -
pubmed
We report postmortem findings in a 46 - year - old
man with dominantly inherited
parkinsonism whose symptoms started at age 28 . -
pubmed
Dystonia is a prominent feature in several of the youngest
patients , but was not present in this
patient . -
pubmed
The case of a 51 year old
woman diagnosed with
hereditary angioneurotic edema (
HANE ) requiring hospital admission on one occasion is presented . -
pubmed
Scedosporium apiospermum pneumonia after autologous bone marrow transplantation . -
pubmed
When the patient failed to improve ,
Scedosporium apiospermum pneumonia was diagnosed and therapy was changed . -
pubmed
Ultrastructural changes in immature articular cartilage were studied after treatment of 5 - wk - old
rats with
ofloxacin - a
fluoroquinolone - and in
magnesium deficiency . -
pubmed
Magnesium deficiency was induced by feeding a
magnesium - deficient diet for 9 days ; the condition was confirmed by measuring the concentrations of the mineral in plasma , bone , and cartilage samples of the
animals by atomic absorption spectrophotometry . -
pubmed
Alterations observed on the ultrastructural level showed striking similarities in
magnesium - deficient
rats and in
rats treated with single doses of 600 mg
ofloxacin / kg
body weight . -
pubmed
Adenomas were obtained from 10
patients with
Cushing ' s disease . -
pubmed
METHODS : The highly vascularized
chicken comb was selected as the
animal model for
hemangiomas . -
pubmed
We studied two groups : 1 ) 82 young healthy normal controls and 2 ) 48
patients with
noninsulin dependent diabetes mellitus (
NIDDM ) and 24 appropriately matched controls . -
pubmed
Effect of low dose
methotrexate on markers of bone metabolism in
patients with
rheumatoid arthritis . -
pubmed
OBJECTIVE : To evaluate markers of bone metabolism in
patients with active
rheumatoid arthritis (
RA ) and the effect of weekly low dose
methotrexate (
MTX ) on bone turnover . -
pubmed
METHODS : Forty - two menstruating female
patients recently diagnosed to have
RA ( mean age 35.4 years , mean disease duration 1.03 years ) were enrolled in this study . -
pubmed
CONCLUSION : In
patients with
RA bone metabolism is affected . -
pubmed
The therapy of weekly low dose
MTX had improved
bone resorption , suggesting that in
patients with RA
MTX might have a bone protective effect by controlling disease activity . -
pubmed
Degenerate disc samples were collected from
low back pain patients undergoing anterior interbody fusion due to severe , discographically verified and
painful disc degeneration , and from the posterior parts of intervertebral discs from 10
patients undergoing microscopic discoidectomy because of
intervertebral herniation . -
pubmed
Pooled colonies of
hygromycin - resistant cells were then tested in
C3H / He mice for their immunotherapeutic properties against the growth of the
breast neoplasm . -
pubmed
The results indicated that
tumor - bearing
mice immunized with the transfected cells survived significantly longer than
mice in various control groups . -
pubmed
Similar beneficial effects were seen in
C57BL / 6 mice injected with a syngeneic
breast carcinoma cell line (
EO771 ) and semiallogeneic , IL-2 - secreting fibroblasts transfected with DNA from
EO771 cells . -
pubmed
[ How should taxonomic
confusions of Caliciviridae , particularly of caliciviruses causing
gastroenteritis in
humans , be resolved ? -
pubmed
We report a 17 - year - old
boy with severe
pyoderma gangrenosum treated successfully with
mycophenolate mofetil and autologous keratinocyte transplantation using an
esterified hyluronic acid delivery system . -
pubmed
METHODS : The study involved 196
patients with
Type 1 diabetes mellitus ( age range 2 - 24 years , onset of
diabetes before the age of 12 years , duration of disease longer than 2 years ) , without clinical and laboratory signs of microvascular complications ; they were divided into three groups ( group 1 - n = 37 , age & lt ; 6 years ; group 2 - n = 71 , age 6 - 12 years ; group 3 - n = 88 , age & gt ; 12 years ) . -
pubmed
A total of 223 healthy controls were matched for age and sex with each group of
patients with
diabetes mellitus . -
pubmed
Efficacy and safety of
clozapine and
olanzapine : an open - label study comparing two groups of
Parkinson ' s disease patients with dopaminergic - induced
psychosis . -
pubmed
Clozapine , an atypical neuroleptic agent , improves dopaminergic - induced
psychosis in
parkinsonian patients without increasing
motor disability . -
pubmed
Therefore , for 12weeks we compared the tolerability and efficacy of
clozapine and
olanzapine in two groups of nine consecutive
parkinsonian psychotic patients treated with these compounds . -
pubmed
All the
patients on
clozapine ( mean starting dose : 13.1+/-7.9mg / d ) completed the study despite reporting a number of adverse events , including
somnolence ,
falls ,
orthostatic hypotension , and
syncope . -
pubmed
In contrast , early withdrawal occurred in three of the nine
patients receiving
olanzapine , due to severe
gait deterioration and
drowsiness ( mean starting dose : 3.9+/-1.3mg / d ) . -
pubmed
Conversely , the six
patients receiving
olanzapine who finished the study experienced aggravated
parkinsonian symptoms , with a 25.5 % worsening in the raw scores and a 24.6 % worsening in the weighted scores ( mean dose : 4.7+/-2.3mg / d ) . -
pubmed
We report a
patient who developed
nitroimidazole - induced
chronic hepatitis following acute exacerbation of
hepatitis three times after
nitroimidazole use . -
pubmed
OBJECTIVE : We sought to evaluate the efficacy of an increased venom dose in
patients allergic to Hymenoptera venom still reacting systemically to a
sting challenge despite immunotherapy with 100 microg of venom every 4 weeks . -
pubmed
RESULTS : While receiving a maintenance dose of 100 microg of venom every 4 weeks for 7 to 38 months , 18
patients reacted systemically to a bee
sting and 22 reacted to a wasp
sting . -
pubmed
After an increase of the maintenance dose to 150 microg , 2 of 4
patients allergic to bee venom ( BV ) and 6 of 6
patients allergic to yellow jacket venom (
YJV ) no longer reacted systemically to the
sting challenge . -
pubmed
Of those 4 individuals not protected by the first dose increase , one
patient allergic to BV ( prior dose of 150 microg ) and one patient
allergic to YJV ( prior dose of 200 microg ) did not react systemically to a further
sting challenge while receiving 200 microg of BV or 250 microg of YJV , respectively . -
pubmed
One
patient allergic to BV who had a systemic reaction to the
sting challenge while receiving 150 microg was not protected after a dose increase to 200 microg ; she later received a dose of 400 microg of BV , and no further
sting challenge was performed . -
pubmed
The
patient allergic to BV who still reacted systemically after a first dose increase to 200 microg was a female
patient with
urticaria pigmentosa . -
pubmed
[ The six minute walking test elicits
lung hyperinflation in
patients with severe
chronic obstructive lung disease ] . -
pubmed
BACKGROUND : Exercise tolerance in
patients with
COPD is highly variable and poorly related to
airways obstruction assessed by FEV1 . -
pubmed
These
patients develop dynamic hyperinflation (
DH ) during an incremental exercise test which can be evaluated through a reduction in inspiratory capacity ( IC ) . -
pubmed
SUBJECTS AND METHODS : Thirty eight stable
COPD patients ( 28 FL and ten non FL during resting breathing , determined by the negative pressure technique ) . -
pubmed
Although no differences were found between groups in 6 MWD ,
dyspnea and HR , a significant reduction in IC after the walking test was observed only in FL
patients ( p & lt ; 0.0001 ) . -
pubmed
CONCLUSIONS : Our results demonstrate that a moderate exercise such as the walking test induces
DH and
hypoxemia in
patients with
COPD and
FL and stresses the importance of assessing DH by measuring IC in these
patients . -
pubmed
Panic disorder patients have reduced
cyclic AMP in platelets . -
pubmed
Abnormalities in the
cyclic AMP system have been described in several
psychiatric disorders but there are no studies in
panic patients . -
pubmed
Average baseline
cyclic AMP of
PD patients was lower than after remission of
panic attacks ( P<0.005 ) and lower than in healthy
volunteers ( P<0.005 ) . -
pubmed
Average
cyclic AMP after remission of
panic attacks was not significantly different than in healthy
volunteers . -
pubmed
Our results suggest that
PD patients without treatment have lower platelets
cyclic AMP levels than healthy
volunteers and that this decrease may be corrected by
clomipramine . -
pubmed
RESULTS : A
human RCC subtractive library with high subtractive efficiency was successfully set up . -
pubmed
CONCLUSIONS : The constructed cDNA subtractive library of
human RCC is a highly efficient one and lays a solid foundation for large scale screening and cloning new and specific oncogenes or
tumor suppressor genes of
RCC . -
pubmed
Development of resistance to
cytarabine (
AraC ) is a major problem in the treatment of
patients with
acute myeloid leukemia (
AML ) . -
pubmed
We report the case of a 9 - year - old
boy presenting with multifocal
paraganglioma partially involving the right suprarenal gland , abdominal paraganglia , and the left para - aortal retropleural region . -
pubmed
Patients with
VHL disease should undergo adrenal - sparing surgery . -
pubmed
Multicentric
inflammation in epicardial coronary arteries of
patients dying of
acute myocardial infarction . -
pubmed
OBJECTIVES : We sought to test the hypothesis of whether inflammatory cell infiltration in
patients dying of an
acute myocardial infarction (
MI ) is a multifocal event involving multiple coronary branches . -
pubmed
METHODS : We performed a systematic flow cytometric study in three groups of autopsied
patients ( group 1 = acute
MI ; group 2 = old
MI ; group 3 = no
ischemic heart disease ) . -
pubmed
A total of 125
patients with locoregional or disseminated
malignant melanoma were randomized to receive
dacarbazine ( 250 mg / m(2 ) days 1 - 5 every 3 weeks ) plus
tamoxifen ( arm A ) or
vindesine ( 3 mg / m(2 ) every week for 6 weeks , then every 2 weeks ) plus
tamoxifen ( arm B ) . -
pubmed
The long - lasting efficacy and effectiveness of DTPa vaccines have been extensively documented and these are now the cornerstone of a large range of combined vaccines including DTPa -
hepatitis B (
HBV ) , DTPa - inactivated
polio (
IPV ) and DTPa -
HBV - IPV . -
pubmed
Four
humeral defects per
dog were implanted with one of each of the putty formulations while the fourth defect was left untreated . -
pubmed
Comparison of dye - dilution and flowmeter estimates of
pulmonary valve incompetence in
dogs . -
pubmed
MATERIALS AND METHODS : Twenty - five
children with intractable
OME were studied . -
pubmed
Thirteen
patients were confirmed
allergy positive by multiallergosorbent test . -
pubmed
Twelve
patients were
allergy negative . -
pubmed
The data collected suggest that
beauvericin exerts a substantial dose- and time - dependent
cytotoxic effect on invertebrate cells , comparable to the effects described in
mammalian cells . -
pubmed
The clinical response and histological analyses were studied in an adjuvant
arthritic rat model . -
pubmed
The fusion protein also suppressed joint swelling ( paw circumference reduced from 5.0 + /- 0.2 to 4.1 + /- 0.1 cm ; paw thickness approximately 2 mm in difference ) and
synovial inflammation in adjuvant
arthritis of
rats . -
pubmed
Plasmodium vivax causes the majority of
malaria outside of sub - Saharan Africa and is an important burden for affected countries . -
pubmed
Scabies is a disease of global proportions in both
human and animal populations , resulting from infestation of the skin with the "
itch " mite
Sarcoptes scabiei . -
pubmed
We report successful treatment by bone marrow transplantation ( BMT ) in an
acute myeloid leukemia (
AML )
patient with
Glanzmann thrombasthenia (
GT ) . -
pubmed
Induction therapy for
AML was performed with frequent platelet transfusions because of the
patient 's severe
hemorrhagic manifestations . -
pubmed
Videoreflective dacryomeniscometry in normal adults and in
patients with functional or primary acquired
nasolacrimal duct obstruction . -
pubmed
PURPOSE : Videoreflective dacryomeniscometry ( VRD ) for evaluation of marginal tear film has not been performed in
patients with
watery eye or in a controlled study . -
pubmed
METHODS : We evaluated with VRD 20
subjects with normal lacrimal drainage function , 21
patients with primary acquired
nasolacrimal duct obstruction (
PANDO ) , 28
patients with functional
nasolacrimal duct obstruction (
FNLDO ) , and a postoperative group of 14
patients derived from the previous two pathologic groups . -
pubmed
In the second trial (
weight loss ) , 29
subjects were similarly randomized to the low or high dairy diets and placed on a caloric restriction regimen ( -500 kcal / d ) . -
pubmed
We present the case of a
patient with a second delivery who arrived at the Gynecology Service due to referring intense
pain in the episiorrhaphy
scar as well as superficial
dyspareunia . -
pubmed
Prevalence , behavioural and social factors associated with
Schistosoma intercalatum and
geohelminth infections in Sao Tome and Principe . -
pubmed
A pilot study was conducted in schoolchildren from three main districts of Sao Tome to assess the relationship between the prevalence of
infections caused by
Schistosoma intercalatum or intestinal
helminths and individual behaviour and social conditions . -
pubmed
Infection rates were 36.2 % for
S. - pubmed
BACKGROUND : The majority of
patients with
thyrotoxicosis are readily diagnosed clinically . -
pubmed
CASE REPORT : A 45 - year - old
woman presented with
choreoathetoid movements of the right upper limb , persistent
vomiting and generalized body
weakness . -
pubmed
Although mechanical ventilation ( MV ) is an important supportive strategy for
patients with
acute respiratory distress syndrome ,
MV itself can cause a type of
acute lung damage termed
ventilator - induced lung injury (
VILI ) . -
pubmed
These medications have been used primarily in
women with
breast carcinoma and also in
children with autonomous
estrogen production , such as
patients with
McCune - Albright Syndrome . -
pubmed
placebo ( bid , n=28 ) in previously diet - treated
subjects with
type 2 diabetes . -
pubmed
CONCLUSION : monotherapy with
vildagliptin is well tolerated and improves glycemic control in diet - treated
subjects with
type 2 diabetes . -
pubmed
Poorer outcome of elderly
patients treated with extended - field radiotherapy compared with involved - field radiotherapy after chemotherapy for
Hodgkin ' s lymphoma : an analysis from the German Hodgkin Study Group . -
pubmed
BACKGROUND : The optimal treatment of elderly
patients with
Hodgkin ' s lymphoma (
HL ) is still a matter of debate . -
pubmed
CONCLUSION : Elderly
patients with early - stage unfavorable
HL generally have a poorer risk profile and outcome when compared with younger
patients . -
pubmed
OBJECTIVE : To evaluate the safety and efficacy of orally administered
ruboxistaurin (
RBX ) as a
mesylate salt in
patients with
diabetic macular edema (
DME ) . -
pubmed
At baseline ,
patients had
DME farther than 300 mum from the center of the macula , an Early Treatment
Diabetic Retinopathy Study
retinopathy severity level from 20 to 47A without prior photocoagulation , and an Early Treatment
Diabetic Retinopathy Study visual acuity of 75 or more letters in the study eye . -
pubmed
We report a case of invasive
lymphangioma of the lung , diagnosed in a 9 - year - old
girl who presented with intractable
hemoptysis and a large pulmonary mass , 10 cm in diameter . -
pubmed
The authors reviewed 79 ( 37
boys , 42
girls ) cases of
empyema thoracis who underwent thoracotomy and decortication between 1990 and 2005 . -
pubmed
METHODS : Sixty - eight
patients were admitted into our hospital for acute
pancreatitis and treated in our ICU for computed tomography - proven severe acute
pancreatitis during the years 1997 to 2004 . -
pubmed
Anesthetized
rabbits were subjected to 60 min of left
coronary artery occlusion and 180 min of reperfusion with ( I / R - VS , n = 8) or without vagal nerve stimulation ( I / R , n = 7 ) . -
pubmed
Rabbits not subjected to
coronary occlusion with ( VS , n = 7 ) or without vagal stimulation ( sham , n = 7 ) were used as controls . -
pubmed
One - week acid suppression trial in uninvestigated
dyspepsia patients with
epigastric pain or burning to predict response to 8 weeks ' treatment with
esomeprazole : a randomized , placebo - controlled study . -
pubmed
BACKGROUND : While empiric acid - suppressive therapy for uninvestigated
dyspepsia patients with symptoms of
epigastric pain or burning is standard practice , it is unknown whether an early response to therapy predicts outcome . -
pubmed
METHODS :
Helicobacter pylori - negative
patients ( aged 18 - 50 years ) in primary care with uninvestigated
epigastric pain or
burning were randomized to
esomeprazole 40 mg q.d.s . -
pubmed
CONCLUSION : A 1 - w acid suppression trial is of limited clinical value for predicting 8 - w response in
patients with symptoms of
epigastric pain or burning . -
pubmed
PURPOSE : To report the results of
patients with early - stage
anal cancer treated using a low - dose , reduced - volume , involved - field chemoradiotherapy protocol . -
pubmed
RESULTS : After a median follow - up of 42 months , only 1
patient ( 4.7 % ) had experienced local
recurrence and has remained disease free after local excision . -
pubmed
Only 1
patient could not complete treatment ( because of Grade 3
gastrointestinal toxicity ) . -
pubmed
Grade 3 - 4 hematologic
toxicity occurred in only 2
patients ( 9.5 % ) . -
pubmed
CONCLUSION : The results of our study have shown that for
patients with
anal carcinoma who have residual microscopic or very - small - volume disease , a policy of low - dose , reduced - volume , involved - field chemoradiotherapy produces excellent local control and disease - free survival , with low rates of acute and late
toxicity . -
pubmed
The effectiveness of acupuncture on
pain and mobility in
patients with
osteoarthritis of the knee : a pilot study . -
pubmed
In this pilot clinical study , acupuncture was incorporated into the standard care for adult
patients with
osteoarthritis of the knee to determine its contribution to
pain relief and improved mobility . -
pubmed
In a prospective , non - randomized controlled study ,
patients with
osteoarthritis of the knee were separated into two groups . -
pubmed
Patients with
osteoarthritis of the knee seemed to experience clinical improvements in six - minute walking distance ,
pain relief and mobility when their standard care was supplemented with acupuncture . -
pubmed
BACKGROUND : In the description of 1 episode
schizophrenia patients , female gender is associated with better social function and a higher degree of compliance , while males exhibit more negative symptoms and a higher degree of abuse . -
pubmed
In addition , in vivo studies demonstrated that oral administration of these two compounds at 20 - 100 mg / kg resulted in similar inhibitory activities against several
animal models of
inflammation /
allergy :
arachidonic acid - induced
mouse ear edema , carrageenan - induced
mouse paw
edema and passive cutaneous
anaphylaxis . -
pubmed
BACKGROUND : There is no consensus on the long - term outcome after unifocalization in
patients undergoing surgery for
pulmonary atresia with
ventricular septal defects (
VSD ) and major aortopulmonary collateral arteries ( MAPCAs ) . -
pubmed
METHODS AND RESULTS : From 1988 to 2006 , 40
patients ( median age 8.5 months ) underwent surgery for
pulmonary atresia ,
VSD , and
MAPCAs . -
pubmed
RESULTS : One hundred and seventy - five
AA patients were included in this analysis . -
pubmed
CONCLUSION : The use and type of induction therapy in
AA patients significantly reduces acute rejection rates and may improve long - term graft outcomes in
AA patients . -
pubmed
Biometric and corneal topographic characteristics in
patients with
Weill - Marchesani syndrome . -
pubmed
PURPOSE : To determine the biometry of ocular structures and corneal topographic characteristics in
patients with
Weill - Marchesani syndrome . -
pubmed
METHODS :
Patients with
Weill - Marchesani syndrome (
syndrome group ) and age - matched normal subjects ( control group ) were evaluated . -
pubmed
RESULTS : The
syndrome group comprised 7 female
patients and the control group , 20 female subjects . -
pubmed
CONCLUSION : Characteristic ocular findings in
patients with
Weill - Marchesani syndrome were a steep , thick cornea with a strong right - left specificity of
corneal astigmatism ; a thick lens ; a short
AL ; and a shallow
ACD . -
pubmed
We recorded the local field potentials ( LFPs ) via implanted electrodes in the rostrolateral part of the periventricular and periaqueductal gray in four
patients ( six electrodes ) who underwent deep brain stimulation for treatment of
neuropathic pain . -
pubmed
One hundred twenty three
patients with
chronic hepatitis C were enrolled in the study . -
pubmed
Infection with
CMV was diagnosed through the detection of
CMV DNA in sera by means of RT - PCR method . -
pubmed
The early virologic response to anti -
HCV therapy was independent of
CMV infection . -
pubmed
Clustering of admission
hyperglycemia ,
impaired renal function and
anemia and its impact on in - hospital outcomes in
patients with ST - elevation
myocardial infarction . -
pubmed
OBJECTIVE : To examine the incidence and inter - relationships between admission
hyperglycemia ,
anemia and
impaired renal function and its impact on clinical outcomes in
patients with
ST - elevation myocardial infarction (
STEMI ) treated with primary PCI . -
pubmed
METHODS : The study group comprised 1880
patients with
STEMI treated with primary PCI , enrolled in a prospective registry . -
pubmed
RESULTS : The primary endpoint of in - hospital
death occurred in 88 ( 4.7 % )
patients . -
pubmed
Hyperglycemia (
glucose & gt;11.1mmol / L ) was present in 352(18.7 % ) ,
anemia ( hematocrit & lt;36 % women , & lt;39 % men ) in 396(21.1 % ) , and increased serum
creatinine ( & gt ; or = 1.2mg / dL women , & gt ; or = 1.3mg / dL men ) in 423(22.5 % )
patients . -
pubmed
Of late , however , two recently developed interventions -- constraint - induced movement therapy ( CIMT ) and bilateral arm training with rhythmic auditory cueing ( BATRAC)--have shown promising results in the treatment of
upper limb paresis in
chronic stroke patients . -
pubmed
The ULTRA -
stroke ( acronym for Upper Limb TRaining After
stroke ) program was conceived to assess the effectiveness of these interventions in
subacute stroke patients and to examine how the observed changes in sensori - motor functioning relate to changes in
stroke recovery mechanisms associated with peripheral stiffness , interlimb interactions , and cortical inter- and intrahemispheric networks . -
pubmed
METHODS / DESIGN : Sixty
patients with a first ever
stroke will be recruited . -
pubmed
The supposed origin of
swine - influenza in the U.S.A. in 1918 and the presence of antibodies to swine -
influenza in the sera of most adult
human beings have led to a suggestion that
swine - influenza is a survival in the
pig of 1918-'flu . -
pubmed
Factors concerned in the immunity of experimental animals to
influenza are discussed- degrees of immunity in the
ferret ; immunity of the nasal passages to big doses of virus ; immunity of the lungs ; immunity to
contact infection . -
pubmed
In planning vaccination of
human beings we wonder:-(1 ) Whether , on general epidemiological grounds , an attempt to vaccinate against
influenza virus is likely to be profitable. -
pubmed
PATIENTS AND METHODS : Two
patients with extended
osteonecrosis of the lower jaw (
osteoradionecrosis or
bisphosphonate - related
osteonecrosis of the jaw ) were treated with partial mandibulectomy . -
pubmed
In this symposium , an international group of multidisciplinary experts discusses the role of tight glycemic control ,
glucose measurement technique and its accuracy ,
glucose variability ,
hypoglycemia , and innovative methods to facilitate
glucose homeostasis in this heterogeneous
patient population . -
pubmed
MATERIALS AND METHODS : We describe the clinical , histological and radiological features of an unusual magnetic resonance imaging ( MRI ) and deep intramuscular location of GCT - ST with fluid - fluid levels ( FFLs ) simulating other
soft tissue tumors or a
hydatid cyst in a 52 - year - old
man . -
pubmed
Pathological examination of excised skin in
patients with
hidradenitis foci is recommended , especially in the case of extra - axillary lesions . -
pubmed
The
patients were classified into 2 groups : A = CIDO with
DS and B = CIDO with
non - DS (
NDS ) . -
pubmed
RESULTS : A total of 227
patients ( male - female = 108:119 ) underwent surgical correction of
CIDO . -
pubmed
Of 227
patients , 86 ( 37.9 % ) were shown to have
DS ( group A ) , and 141 ( 62.1 % ) were
NDS patients ( group B ) . -
pubmed
It is concluded that
DS negatively impacts the management and outcome of
patients with
CIDO . -
pubmed
Potassium deficiency induces the biosynthesis of
oxylipins and
glucosinolates in
Arabidopsis thaliana . -
pubmed
METHODS : Between July 2003 and November 2008 , 30 relapsed
SCLC patients receiving 35 mg / m(2)/day of
AMR were evaluated . -
pubmed
Febrile neutropenia occurred in three
patients ( 10 % ) . -
pubmed
We developed a
pig kidney allograft model of
DGF and evaluated the cytoprotective effects of inhaled
carbon monoxide (
CO ) . -
pubmed
In vitro in
pig renal epithelial cells ,
CO blocks
anoxia - reoxygenation - induced cell
death while promoting proliferation . -
pubmed
This large
animal model of DGF can be utilized for testing therapeutic strategies to reduce or prevent
DGF in
humans . -
pubmed
Supratentorial PNET in a young
child . -
pubmed
These agents include cytomegalovirus ;
Epstein - Barr virus ;
herpes simplex virus ;
varicella - zoster virus ;
human herpesvirus 6 , 7 , and 8 ;
human parvovirus B19 ; adenoviruses among others . -
pubmed
Human herpesviruses 6 , 7 , and 8 ,
human parvovirus B19 , and adenoviruses can also be present with features of
acute liver injury and occasionally as
fulminant hepatitis . -
pubmed
METHODS : A prospective study of a series of 9
patients with recent
retinal vein occlusion with
macular edema treated with sustained - release
dexamethasone 0.7 mg intravitreal implant was performed . -
pubmed
RESULTS : Nine eyes of 9 consecutive
patients treated with a total of 9 sustained - release
dexamethasone 0.7 mg intravitreal implants for
macular edema associated with
retinal vein occlusion were included . -
pubmed
Five
patients had central
retinal vein occlusion and 4
patients had branch
retinal vein occlusion . -
pubmed
Accentuated
ischemia was associated in 2/5
patients with central
retinal vein occlusion . -
pubmed
CONCLUSIONS : In
patients with
macular edema in
retinal vein occlusion , sustained - release
dexamethasone 0.7 mg intravitreal implant may be an effective treatment option to control
macular edema . -
pubmed
We present the case of a
patient with an aberrant right subclavian artery with a small calcified
aneurysm in a
Kommerell ' s diverticulum that caused
chest pain and
dysphagia ; the patient underwent a procedure combining endovascular and surgical treatment . -
pubmed
This relationship between these attentional networks and
anxiety may in part explain the problems in the day - to - day functioning of these
patients . -
pubmed
Should all patients with
pulmonary hypertension undergo
HIV serologic testing ? -
pubmed
OBJECTIVES : To evaluate the yield of screening
patients with
pulmonary hypertension (
PH ) for
human immunodeficiency virus ( HIV ) infection . -
pubmed
RESULTS : We identified 445 patients with
PH who had serologic testing for
HIV antibody . -
pubmed
Only 1 patient ( 0.2 % ; 95 % confidence interval , 0.0%-1.2 % ) was positive for
HIV , and this was the only patient who had a known history of
HIV infection . -
pubmed
The patient who tested positive for
HIV had
PAH , yielding an estimated prevalence of positive
HIV testing in that subgroup of 0.4 % ( 95 % confidence interval , 0.0%-2.5 % ) ; 6 other patients with
PAH ( 2.7 % ) had risk factors for
HIV but negative serology . -
pubmed
CONCLUSIONS : To our knowledge , this is the first study examining the yield of screening patients with
PH for
HIV using serologic testing . -
pubmed
Patients with
PAH should be assessed for risk factors for
HIV before testing for
HIV in low - risk populations . -
pubmed
MATERIALS AND METHODS : A total of 67
patients , 32
premalignant lesions and other 35 frank
oral carcinomas , were included in the study . -
pubmed
BACKGROUND : It is well - known that
tumor exerts nonmetastatic systemic effect on
organism caused the development of
paraneoplastic syndrome (
PNS ) . -
pubmed
In this review , we discuss the development of the cranial vault and explain the basic science behind
craniosynostosis in
humans as well as in
animal models and how these studies may lead to future advances in
craniosynostosis treatments . -
pubmed
Moreover , when
cervical degenerative diseases are treated with a combination of decompression and posterior instrumented fusion ,
patients are at increased risk for
C-5 palsy . -
pubmed
RESULTS : Ten ( 11.9 % ) of 84
patients developed
postoperative C-5 palsy . -
pubmed
CONCLUSIONS :
Patients with preoperative
foraminal stenosis , posterior shift of the spinal cord , and additional iatrogenic
foraminal stenosis due to cervical alignment correction were more likely to develop
postoperative C-5 palsy after posterior instrumentation with fusion . -
pubmed
In this study , we tested the ability of
Fasciola hepatica total extract ( TE ) to induce tolerogenic properties in
CpG - ODN ( CpG ) maturated DC , to then evaluate the therapeutic potential of these cells to diminish the inflammatory response in collagen induced
arthritis (
CIA ) . -
pubmed
BACKGROUND :
Glioblastoma (
GBM ) is the most common primary malignant
human brain tumor with a poor prognosis . -
pubmed
MATERIAL AND METHODS : 199
patients with primary
GBM consecutively operated and histologically reviewed according to the 2007 WHO scheme , were included . -
pubmed
RESULTS : Mean age of the
GBM patients at diagnosis was 62 years ( range 21 - 84 ) . -
pubmed
In addition ,
females ,
tumors with angiocentric growth , with pseudopalisades , or without lymphocyte infiltration were related to shorter survival in univariate analyses ( p & lt ; 0.05 ) . -
pubmed
CONCLUSION : Our findings confirm the strong prognostic value of age , treatment , performance score , and localization for
glioblastoma patients . -
pubmed
Outcomes after single lung transplantation in older
patients with
secondary pulmonary arterial hypertension . -
pubmed
Neuralgia - inducing cavitational
osteonecrosis in a
patient seeking dental implants . -
pubmed
Cytotoxicity studies of DL - Qdots bearing
carboxyl groups ( DL - Qdots -
COOH ) were carried out against
human cervical ( HeLa )
cancer cells to elicit no apparent toxicity even at high concentrations of 300 mug mL(-1 ) and 24 h of incubation . -
pubmed
To demonstrate their potential biomedical application , DL - Qdots -
COOH were further conjugated with
folate for staining in
HeLa ,
human liver
carcinoma (
HepG2 ) , and
human breast (
MCF-7 )
cancer cells . -
pubmed
Proteomic analysis of
arsenic - exposed
zebrafish (
Danio rerio ) identifies altered expression in proteins involved in
fibrosis and lipid uptake in a gender - specific manner . -
pubmed
Despite widespread intervention efforts to curtail the spread of
HIV , heterosexual transmission of
HIV continues to drive the
HIV / AIDS epidemic in the United States , especially among women . -
pubmed
The aim of the study was to investigate the difference in clinical features of
type 2 diabetic patients with and without visceral fat accumulation , focusing on vascular complications and changes in
BMI . -
pubmed
METHODS : We enrolled 88 Japanese hospitalized
type 2 diabetic patients . -
pubmed
RESULTS :
Hypertension ,
dyslipidemia and
cardiovascular diseases were significantly more in the
patients with
abdominal obesity . -
pubmed
The prevalence of
cardiovascular disease in the non - obese
patients (
BMI & lt ; 25 kg / m2 ) with
abdominal obesity were similar in obese
patients (
BMI & gt;=25 kg / m2 ) . -
pubmed
The mean
BMI of the
patients with
abdominal obesity was & lt ; 25 kg / m2 at 20 years of age , but reached maximum to more than 30 kg / m2 in the course . -
pubmed
Furthermore , substantial portion of the
type 2 diabetic patients ( 52 % in males and 43 % in females ) were not
obese at 20 year - old (
BMI & lt ; 25 kg / m2 ) , but developed
abdominal obesity by the time of admission . -
pubmed
CONCLUSION : These results emphasize the need to control multiple risk factors and prevent
atherosclerotic disease in
patients with
abdominal obesity . -
pubmed
Patient cases of
hepatotoxicity involving the use of
nefazodone ,
trazodone ,
duloxetine ,
bupropion , and
sertraline are linked to causing
death in its users . -
pubmed
Antidepressant - induced
liver injury can occur in the absence of identifiable , underlying risk factors such as
cirrhosis and
hepatitis infection ; only a few cases of
hepatic injury involve
patients with
chronic hepatitis infection . -
pubmed
After administration of treatment , of Treg content in spontaneous
SAH patients increased progressively and became comparable with those in the other two groups at the third and fourth lumbar punctures . -
pubmed
Spontaneous
SAH patients showed significantly lower GCS , NIHSS , and VAS with shorter hospital stay than the traumatic
SAH patients . -
pubmed
CONCLUSION :
Treg deficiency can be an important mechanism for the occurrence of spontaneous
SAH , and a higher level of Treg indicates a better outcome of the
patients . -
pubmed
Neuroprotective effects of
quetiapine on neuronal apoptosis following experimental transient focal
cerebral ischemia in
rats . -
pubmed
A 75 - year - old Japanese
man presented with
pruritic blisters and
macules on his trunk and extremities . -
pubmed
New
blisters continued to erupt during the period in which the
patient used the cellulose triacetate membrane dialyzer , and even after the use of
clobetasol propionate . -
pubmed
Compared to the other three groups ,
Hcy plasma levels were reduced in early - onset
ALS patients but
Met levels were similar . -
pubmed
Patients with
atrial fibrillation have nearly twice the risk of
stroke in first 30 days of starting
warfarin . -
pubmed
Dietary inclusion of
sorghum (
Sorghum bicolour ) straw dye protects against
cisplatin - induced
nephrotoxicity and oxidative stress in
rats . -
pubmed
OBJECTIVE : This study sought to investigate the modulatory effect of dietary inclusion of Sorghum straw dye on
cisplatin - induced
nephrotoxicity and antioxidant status in
rats . -
pubmed
DISCUSSION AND CONCLUSION : The study suggests that dietary inclusion of
sorghum straw dye as colorants could protect against oxidative stress and
cisplatin - induced
nephrotoxicity . -
pubmed
The purpose of the current study was to validate the use of CT for selection against
osteochondrosis in
pigs by calculating positive predictive value and comparing it to the positive predictive value of macroscopic evaluation , using histological examination as the reference standard . -
pubmed
The current histologically validated observations can potentially be extrapolated to diagnostic monitoring of
juvenile osteochondritis dissecans in
children , or to animal models of
human juvenile articular cartilage injury and repair . -
pubmed
OBJECTIVE : To investigate grey ( GM ) and
white matter ( WM ) abnormalities and their effects on cognitive and behavioral deficits in a large , phenotypically and genotypically well - characterized cohort of classic adult (
aDM1 , age at onset > = 20 years ) or juvenile ( jDM1 , age at onset < 20 years )
patients with
myotonic dystrophy type 1 (
DM1 ) . -
pubmed
METHODS : A case - control study including 51
DM1 patients ( 17 jDM1 and 34 aDM1 ) and 34 controls was conducted at an academic medical center . -
pubmed
RESULTS :
DM1 patients showed a high prevalence of
WMHs , severe regional GM
atrophy including the key nodes of the sensorimotor and main cognitive brain networks , and WM microstructural damage of the interhemispheric , corticospinal , limbic and associative pathways . -
pubmed
While
aDM1 patients had severe patterns of GM
atrophy and
WM tract damage , in
jDM1 patients WM abnormalities exceeded GM involvement . -
pubmed
Addiction - related genes in
gambling disorders : new insights from parallel
human and pre - clinical models . -
pubmed
We investigated whether rGT performance and associated risk gene expression in the
rat 's brain could provide cross - translational understanding of the neuromolecular mechanisms of
addiction in
DG . -
pubmed
We genotyped tagSNPs ( single - nucleotide polymorphisms ) in 38 addiction - related genes in 400
DG and 345 non - DG
subjects . -
pubmed
To our knowledge , the use of
human genetics , pre - clinical models and gene expression as a cross - translation paradigm has not previously been attempted in the field of
addictions . -
pubmed
Spore mixtures of six
strains of non - proteolytic
C. - pubmed
The healing effect of scrophularia striata on experimental
burn wounds infected to
pseudomonas aeruginosa in
rat . -
pubmed
BACKGROUND : The cause of
death in
burn patients after 48 hours of hospitalization has been reported to be
bacterial infections . -
pubmed
This study aims to investigate the medicinal effect of the ethanolic extract of
Scrophularia striata on
burn wound infection in in - vivo and in - vitro in comparison with
silver sulfadiazine (
SSD ) . -
pubmed
RESULTS : The rate of
wound healing was significantly greater in
S. - pubmed
Nephrotic range
proteinuria as a strong risk factor for rapid renal function decline during pre - dialysis phase in
type 2 diabetic patients with severely
impaired renal function . -
pubmed
The predictive power of
proteinuria , especially
nephrotic range
proteinuria , for
progressive renal deterioration has been well demonstrated in diabetic
patients with normal to relatively preserved renal function . -
pubmed
However , little is known about the relationship between severity of
proteinuria and renal outcome in pre - dialysis
diabetic patients with severely
impaired renal function . -
pubmed
METHODS : 125 incident dialysis
patients with
type 2 diabetes were identified . -
pubmed
RESULTS : In total , 103
patients ( 82.4 % ) had
nephrotic range
proteinuria . -
pubmed
Compared to
patients without
nephrotic range
proteinuria ,
patients with
nephrotic range
proteinuria showed significantly faster renal function decline ( 0.46 [ 0.24 - 1.25 ] versus 1.07 [ 0.64 - 1.54 ] ml / min/1.73 m(2 ) per month ; p = 0.007 ) . -
pubmed
CONCLUSION :
Nephrotic range
proteinuria is the predominant renal risk factor in
type 2 diabetic patients with severely
impaired renal function receiving pre - dialysis care . -
pubmed
CONCLUSION : Among these three
strains tested ,
P. - pubmed
Characterization of the
Prediabetic State in a Novel
Rat Model of
Type 2 Diabetes , the ZFDM
Rat . -
pubmed
At 6 - 8 weeks of age , fa / fa male
rats exhibited mild
glucose intolerance and severe
insulin resistance . -
pubmed
At 10 - 12 weeks of age , fa / fa male
rats exhibited marked
glucose intolerance as well as severe
insulin resistance similar to that at the earlier age . -
pubmed
RESULTS : Of the 142
patients with
sickle cell anaemia , 110 ( 77.5 % ) had the alphaalpha+thalassaemia deletion . -
pubmed
Amongst the
patients older than 60 months , 15 ( 83.3 % ) of those without alphaalpha+
thalassaemia had significant
hepatomegaly of greater than 4 cm compared to 36 ( 45.6 % ) of those with
alpha + thalassaemia ( p=0.003 ) . -
pubmed
Concurrent
alpha thalassemia might be a protective trait against significant
hepatomegaly in
sickle cell anaemia patients more than 60 months of age at Mulago hospital . -
pubmed
The scales most commonly used by the therapeutic team for assessment of a
patient with
traumatic brain injury (
TBI ) include deficit scales , functional scales , and scales assessing quality of life . -
pubmed
The purpose of this study was to establish the relationships between the particular scales used for assessment of
patients with
TBI . -
pubmed
METHODS : This multicenter study included 159
patients with
TBI . -
pubmed
RESULTS :
Patients with mild
impairment of consciousness were most numerous in the examined group at both admission and discharge , ie , 118 ( 78.8 % ) and 134 patients ( 89.3 % ) , respectively . -
pubmed
Genetically
epilepsy - prone
rats ( GEPRs ) and DBA/2
mice : Two
animal models of
audiogenic reflex epilepsy for the evaluation of new generation AEDs . -
pubmed
This review summarizes the current knowledge about DBA/2
mice and genetically
epilepsy - prone
rats ( GEPRs ) and discusses the contribution of such
animal models on the investigation of possible new therapeutic targets and new anticonvulsant compounds for the treatment of
epilepsy . -
pubmed
Abnormal activities of enzymes involved in
catecholamine and
serotonin synthesis and metabolism were reported in these models , and as a result of all these abnormalities ,
seizure susceptibility in both
animals is greatly affected by pharmacological manipulations of the brain levels of
monoamines and , prevalently ,
serotonin . -
pubmed
Audiogenic models of
epilepsy have been used not only for reflex
epilepsy studies , but also as
animal models of epileptogenesis . -
pubmed
MI - associated
blood leukocytosis correlates inversely with
patient survival , yet the signals driving heightened leukocyte production after
MI remain incompletely understood . -
pubmed
CONCLUSIONS :
Participants with
chronic schizophrenia made significant cognitive gains after 50 hours of intensive computerized training delivered as a stand - alone treatment , but no improvement in symptoms or functioning . -
pubmed
Inflammatory Mediators and Clinical Outcome in
Patients With Advanced
Heart Failure Receiving Cardiac Resynchronization Therapy . -
pubmed
Antibodies from donor B cells perpetuate
cutaneous chronic graft - versus - host disease in
mice . -
pubmed
With a
murine cGVHD model using DBA/2 donors and BALB / c recipients , we have shown that wild - type ( WT ) grafts induce persistent
cGVHD with damage in the thymus , peripheral lymphoid organs , and skin , as well as cutaneous T helper 17 cell ( Th17 ) infiltration . -
pubmed
The aim of our study was to analyze the clinicopathological factors , compare treatment options , and evaluate outcome in
patients with
PT . -
pubmed
The main goal of the study was to investigate whether the quantitative changes of Treg subpopulations are related to the clinical status of
patients with
LN . -
pubmed
Fifty - four adult
SLE patients divided into two groups according to their SLEDAI and renal SLEDAI scores were enrolled into the study . -
pubmed
The combined experiences of the authors , including a
diabetes predictive model for oral health settings , the efficacy and effectiveness of
human immunodeficiency virus screening in a dental setting , the feasibility of using a decision support tool for
tobacco cessation , and the effectiveness of integrating oral health education with comprehensive health services for people living with
human immunodeficiency virus , have contributed to this concept . -
pubmed
Predictors of
pain response in
patients undergoing endoscopic ultrasound - guided neurolysis for
abdominal pain caused by
pancreatic cancer . -
pubmed
RESULTS : A good
pain response was obtained in 77.7 % and 67.9 % of
patients at 1 and 4 weeks , respectively . -
pubmed
We hereby sought to explore the association of inter - arm BP difference with ICAS and ECAS in
stroke - free
hypertensive patients in Chinese population . -
pubmed
Appraisal of
inflammation - based prognostic scores in
patients with unresectable perihilar
cholangiocarcinoma . -
pubmed
METHODS : The modified Glasgow Prognostic Score ( mGPS ) , Neutrophil Lymphocyte Ratio ( NLR ) , Platelet Lymphocyte Ratio , and Prognostic Nutritional Index , were retrospectively assessed in 219
patients with unresectable perihilar
cholangiocarcinoma . -
pubmed
CONCLUSIONS : Both mGPS and NLR are independent prognostic factors and pivotal in refining
patient stratification in unresectable perihilar
cholangiocarcinoma . -
pubmed
Effects of Taekwondo intervention on balance in
children with
autism spectrum disorder . -
pubmed
The purpose of this study was to investigate the effects of an 8 - week Taekwondo ( TKD ) intervention on balance in
children with
autism spec - trum disorder (
ASD ) . -
pubmed
A total of 14
children with
ASD participated in this study . -
pubmed
KSHV prevalence is high in several populations with high prevalence of
HIV , leading to increased risk of development of
Kaposi ' s sarcoma (
KS ) . -
pubmed
While current assays are reliable for detecting antibodies to
KSHV , none are routinely utilized to identify individuals with
KSHV infection and thus at increased risk for
KS due to assay complexity , lack of access to testing , and cost , particularly in resource - limited settings . -
pubmed
This study demonstrates assay performance by measuring antibody reactivity for
KSHV and
HIV-1 in a collection of clinical specimens from patients with biopsy - proven
KS and sourced negative controls . -
pubmed
The
KSHV assay correctly identified 155 of 164 plasma samples from patients with biopsy - proven
KS and 85 of 93
KSHV antibody ( Ab)-negative samples for a sensitivity of 95.1 % and specificity of 91.4 % . -
pubmed
Depending on the context , after sensing environmental antigens , commensal
microorganisms , pathogenic agents , or antigens from the diet , dendritic cells may drive either different effector adaptive immune responses or tolerance , avoiding
tissue damage . -
pubmed
Majority of
patients ( 80 % ) experienced similar
pain during axillary view compared to contralateral MMG . -
pubmed
The goal of the present study was to investigate the effects of long - term and short - term consumption of
quercetin ,
( -)- epicatechin , and
ibuprofen on the lifespan , resistance to stress factors (
paraquat ,
hyperthermia , gamma - radiation , and
starvation ) , as well as age - dependent physiological parameters ( locomotor activity and fecundity ) of
Drosophila melanogaster . -
pubmed
BACKGROUND : Detection of
cancer and subsequent chemotherapy can lead to clinical
depression in many
cancer patients . -
pubmed
OBJECTIVES : The study was conducted to find out the extent of
depression in
cancer patients undergoing chemotherapy and determine the factors associated with
depression . -
pubmed
A novel dimorphic pathogen ,
Emergomyces orientalis ( Onygenales ) , agent of
disseminated infection . -
pubmed
When we used a
mouse tumor implantation model to evaluate pCD63 - OVA as a therapeutic vaccine , the EV - delivered DNA vaccination significantly inhibited
tumor growth compared with the control DNA vaccinations . -
pubmed
METHODS : We applied US Food and Drug Administration ( FDA ) and insurance eligibility criteria for
ALI and EVO to 1090
hypercholesterolemic patients serially referred over 3 years who then received & gt;=2 months maximal - tolerated dose of standard - of - care LDL
cholesterol - lowering therapy ( MTDLLT ) with follow - up LDLC & gt;=70 mg / dL. -
pubmed
RESULTS : Of the 1090
patients , 140 ( 13 % ) had
HeFH by clinical diagnostic criteria and/or
CVD with LDLC & gt;100 mg / dL despite & gt;=2 months on MTDLLT , meeting FDA insurance criteria for
ALI or
EVO therapy . -
pubmed
Recent observational studies have reported that
patients with low circulating levels of
vitamin D experience larger
infarct volumes and worse functional outcomes after
ischemic stroke compared to those with sufficient levels . -
pubmed
Male C57Bl6
mice ( six week old ) were assigned to either a control or
vitamin D deficient diet for four weeks prior to
stroke . -
pubmed
METHODS : A total of 13 male
patients underwent IRE of focal low - risk
PCa and were included in this analysis . -
pubmed
PURPOSE : To systematically analyse the differences between cycloplegic and noncycloplegic
refractive errors ( RE ) in
children and to determine if the predictive value of noncycloplegic RE in categorizing RE can be improved . -
pubmed
PATIENTS AND METHODS : Electrochemotherapy with
bleomycin was performed on 17
hepatocellular carcinomas in 10
patients using a previously established protocol . -
pubmed
CONCLUSIONS : Electrochemotherapy of
hepatocellular carcinoma proved to be a feasible and safe treatment in all 10
patients included in this study . -
pubmed
Electrochemotherapy is predominantly applicable in
patients with
impaired liver function due to
liver cirrhosis and/or with lesions where a high - risk operation is needed to achieve curative intent , given the intra / perioperative risk for high morbidity and mortality . -
pubmed
This is limited by correct surgical technique , the age of the
patient , delay from the time of
injury and the mechanism or localization of the
injury . -
pubmed
In this secondary intention - to - treat analysis , we assessed the change in estimated
glomerular filtration rate ( eGFR ) over a 44 - month follow - up period in
patients with ( n=3784 ) and those without ( n=4615 )
diabetes . -
pubmed
Compared with
patients treated with
enalapril , those treated with
sacubitril /
valsartan had a slower rate of decline in eGFR ( -1 3 vs -1 8 mL / min per 1 73 m2 per year ; p<0 0001 ) , and the magnitude of the benefit was larger in
patients with versus those without
diabetes ( difference 0 6 mL / min per 1 73 m2 per year [ 95 % CI 0 4 - 0 8 ] in
patients with vs 0 3 mL / min per 1 73 m2 per year [ 0 2 - 0 5 ] in those without
diabetes ; pinteraction=0 038 ) . -
pubmed
The incremental benefit of
sacubitril /
valsartan in
patients with
diabetes was no longer apparent when changes in
eGFR were adjusted for urinary
cyclic guanosine monophosphate ( p=0 41 ) . -
pubmed
Purpose : This study aimed at investigating the long - term outcomes of
oxaliplatin and
capecitabine (
XELOX ) administered concurrently with preoperative radiation and extended to the resting period in
patients with high - risk locally advanced
rectal cancer ( LARC ) . -
pubmed
Twelve ( 26.7 % )
patients developed local
recurrence or distant
metastasis , including 10 ( 22.2 % )
patients developing distant
metastasis only , 1 ( 2.2 % )
patient local
recurrence only , and 1 ( 2.2 % )
patient both local
recurrence and distant
metastasis . -
pubmed
Of the 296 betaHS , 220 ( 74 % ) were
GAS , 52 ( 17.5 % ) were Group G streptococci and 11 ( 3.7 % ) , 10 ( 3.3 % ) and three ( 1 % ) were Group B streptococci , Group C streptococci and
Group F streptococci , respectively . -
pubmed
Berberine (
BBR ) , an active component of a Chinese herb
Coptis chinensis French , has been shown to have anti - inflammatory properties through suppressing macrophage migration in various
inflammation animal model . -
pubmed
The goal of this study was to examine
BBR 's effect on
inflammation and
IAs formation in a
rodent aneurysm model . -
pubmed
A
rodent aneurysm model was induced in 5 - week - old male
Sprague Dawley ( SD ) rats by intracranial surgery , then these
rats were orally administrated 200 mg / kg / day
BBR for 35 days . -
pubmed
Urinary and Plasma Metabolomics Identify the Distinct Metabolic Profile of Disease State in Chronic
Mouse Model of
Multiple Sclerosis . -
pubmed
Graphical Abstract Untargeted urinary metabolomics of a chronic
mouse model of
multiple sclerosis identified
Phenylalanine ,
tyrosine &
amp ;
tryptophan metabolism as the significantly altered metabolic pathway . -
pubmed
Speech Impairment in
Boys With
Fetal Alcohol Spectrum Disorders . -
pubmed
Purpose : This study set out to chart the speech and speech motor characteristics in
boys with
FASD to profile the concomitant
speech impairment and identify possible underlying mechanisms . -
pubmed
Method : Ten
boys with
FASD ( 4.5 - 10.3 years old ) and 26 typically developing
children ( 4.1 - 8.7 years old ; 14
boys , 12
girls ) participated in the study . -
pubmed
Results : The
boys with
FASD showed reduced scores on all tasks as well as a deviant pattern of correlations between production and perception tasks and intelligibility compared with the typically developing
children . -
pubmed
Conclusions : Findings indicate that the
speech impairment in
boys with
FASD results from a combination of deficits in multiple subsystems and should be approached as a disorder rather than a developmental delay . -
pubmed
Considerable progress has been made in the development of approaches for
HIV incidence estimation based on a cross - sectional survey for biomarkers of recent
infection . -
pubmed
METHODS :
Patients who called for EMS due to
pain in a part of western Sweden were included . -
pubmed
Attention - deficit / hyperactivity disorder (
ADHD ) is a
neurodevelopmental disorder that affects approximately 8%-12 % of
children worldwide . -
pubmed
Although evidence - based treatments can reduce
ADHD symptoms in a substantial portion of affected
individuals , there is yet no curative treatment for
ADHD . -
pubmed
Besides ,
OA rats showed obvious
synovial tissue hyperplasia ,
inflammation and
cartilage injury of femoral condyle , as well as increased
inflammation and
cartilage injury scores , and apoptosis of synoviocytes and chondrocytes . -
pubmed
Alcohol Extracts From
Ganoderma lucidum Delay the Progress of
Alzheimer ' s Disease by Regulating DNA Methylation in
Rodents . -
pubmed
Age - related changes in methylation are involved in the occurrence and development of
tumors ,
autoimmune disease , and
nervous system disorders , including
Alzheimer ' s disease (
AD ) , in elderly
individuals ; hence , modulation of these methylation changes may be an effective strategy to delay the progression of
AD pathology . -
pubmed
In this study , the
AD model
rats were used to screen the main active extracts from the
mushroom ,
Ganoderma lucidum , for anti - aging properties , and their effects on DNA methylation were evaluated . -
pubmed
We investigated the waveform patterns of automatically detected high - frequency oscillations in 13
patients with
epilepsy and 5 control subjects , with an average of 73 subdural and intracerebral electrodes recorded per
patient . -
pubmed
Consistently in all
patients , the stereotypical high - frequency oscillations with the highest degree of waveform similarity were localized within the
seizure onset zones only , whereas the channels generating high - frequency oscillations embedded in random waveforms were found in the functional regions independent of the epileptogenic locations . -
pubmed
Giant aneurysm arising from anomalous branch of the middle cerebral artery in a paediatric
patient : case report and review of literature . -
pubmed
Conclusion : Motivational interviewing promotes treatment adherence among
patients with
chronic obstructive pulmonary disease . -
pubmed
Here we model
chronic intestinal damage in
zebrafish larvae using the nonsteroidal antiinflammatory drug ( NSAID )
Glafenine . -
pubmed
However , there are few reported cases of
super - refractory status epilepticus in
children . -
pubmed
We illustrate that
super - refractory status epilepticus can be the first manifestation of small vessel
cPACNS in previously healthy
children and that symptomatic management of
seizures with concurrent immunosuppression to treat the underlying pathology resulted in favorable neurologic outcomes . -
pubmed
Cancer patients are at increased risk of developing
thrombosis , comorbidity that has been associated with increased neutrophil counts and the formation of neutrophil extracellular traps ( NETs ) . -
pubmed
The aim of this study was to investigate whether
artemisinin derivatives
artesunate and
dihydroartemisinin could enhance the immunogenicity of inactivated
rabies virus in
mice . -
pubmed
Administration of
artesunate or
dihydroartemisinin by intramuscular injection at a dose of 5 mg / kg did not cause body
weight loss and unusual symptoms in
mice . -
pubmed
Tremendous progress has been made over the past three decades in the fight against the
human immunodeficiency virus (
HIV ) epidemic ; however , children experienced substantial physical and psychosocial effects of
HIV infection . -
pubmed
Giant cell arteriitis (
GCA ) is the most common
systemic vasculitis in
patients > = 50 years . -
pubmed
Our previous studies showed that
matrine (
MAT ) , a natural alkaloid component extracted from the
Sophora root , has beneficial effects in
EAE through immunomodulation . -
pubmed
The sample consisted of 66 preterm
infants of both sexes , aged 18 - 36 months , divided into two groups : AIG Group 39 neonates with weight appropriate to the gestational age , 26 with normal hearing and 13 with
altered hearing ; and PIG group 27 neonates small for gestational age , 18 with normal and 9 with
altered hearing . -
pubmed
Although its history began more than 30 years ago , it remains one of the most used drugs in
children with a leading role in the medical care of
children with
allergic diseases . -
pubmed
Cetirizine use is licensed for paediatric
patients for the treatment of
allergic rhinitis , and chronic spontaneous
urticaria , in Europe in
children older than 2 years old and in the USA in
children older than 6 months old . -
pubmed
Compounds 1 and 6 also exhibited moderate antibacterial activities against sensitive ( ATCC 29213 ) and drug - resistant ( ATCC 700699 )
strains of
Staphylococcus aureus . -
pubmed
As the biomedical community races to disentangle the unknowns associated with
severe acute respiratory syndrome coronavirus 2 , the virus responsible for causing
coronavirus disease , the link between diminished immune function and individuals with
obesity raises important questions about the possibility for greater viral pathogenicity in this population . -
pubmed
Patients were evaluated for
postoperative pain ,
swelling , and
trismus . -
pubmed
RESULTS : We identified 15
patients ( 4
male , 11
female ; mean age 53.7 years ) who had RYGB on average 11.7 years ( range 1 - 32 ) years before diagnosis of
biliary obstruction . -
pubmed
Fourteen
patients reported
abdominal pain , 5 had
nausea /
emesis , 12 had elevated liver function tests , and 6 had ascending
cholangitis . -
pubmed
Twenty - six studies including 23 826
patients with or without
PAD who underwent ERCP were evaluated . -
pubmed
This
Valproate - D - Nanogel was prepared through copolymerizing carboxymethyl chitosan with
diallyl disulfide and subsequent grafting with
valproate to reverse the drug - resistance in
cisplatin - resistant
human lung adenocarcinoma cancer . -
pubmed
The whole - genome sequencing ( WGS ) allowed evaluating the
genome stability of
BCG strains and the impact of spontaneous heterogeneity in seed and commercial lots on the efficacy of
BCG - vaccines in different countries . -
pubmed
Sequence variations in several genes of seed lot 361 did not alter the
genomic stability and viability of the vaccine and appeared accumulated in isolates during the survival in the
human organism . -
pubmed
The dysregulation of miR-451a was revealed both in primary
tumors and in
patients ' sera . -
pubmed
The study of functional and structural changes in these components of the eye will provide useful information to identify
subjects with
diabetes at risk of
diabetic peripheral neuropathy and
dementia . -
pubmed
PATIENT CONCERNS : A 77 - year - old
man with
diplopia was referred to our department by an opthomologist who had diagnosed the
patient with right
abducens nerve palsy . -
pubmed
Meditation for Improved Clinical Outcomes in
Patients with Implantable Defibrillators for
Heart Failure- Pilot Study . -
pubmed
We hypothesized that meditation by reducing emotional reactivity would have beneficial effect in reducing
arrhythmias compared to control
patients . -
pubmed
Methods :
Patients known to have
CHF and implantable cardioverter defibrillators ( ICD ) were randomized to Vipassana meditation or usual care control group . -
pubmed
Results :
Patients ( n=25 , 65 % male , mean LVEF 25 % ,
HTN 38 % ,
Diabetes 12 % ,
coronary artery disease 38 % , NYHA class 2.2 ) were followed for 79 + 36 months . -
pubmed
Conclusions : In this first pilot study of meditation in
CHF patients with
ICD , during long term follow up , there is a trend for improved survival and reduced
arrhythmias in
patients randomized to meditation . -
pubmed
Method Thirty - six monolingual English - speaking
children aged 4 and 5 years , half with
SSD and half with typical speech and language skills , participated in this study . -
pubmed
Modified surgical treatment for a
patient with
neurofibromatosis scoliosis : A case report . -
pubmed
CASE SUMMARY : A 44 - year - old
woman presented with progressive
kyphosis for more than 10 years and
low back pain for 2 years . -
pubmed
CONCLUSION : For this
patient with severe
deformity , the correction treatment of Ponte osteotomy followed by satellite rod technique in the region of the apical vertebra and the technique of pedicle screws and dual iliac screws had been applied , and successful clinical outcomes were achieved . -
pubmed
Spatial navigation and dual - task performance in
patients with
Dementia that present partial dependence in instrumental activity of daily living . -
pubmed
However , more low - cost assessments are necessary to better understand the process of IADL in
patients with
Dementia . -
pubmed
Objective : To compare cognitive , motor and cognitive - motor performance at different stages of dependence on IADL in
patients with
Dementia . -
pubmed
Methods :
Dementia patients ( n = 53 , age range : 63 - 94 ) and healthy older
adults ( n = 39 , age range : 62 - 97 ) were included , and those with
Dementia were separated into IADL 1 ( n = 18 ) , IADL 2 ( n = 17 ) , IADL 3 ( n = 18 ) . -
pubmed
Also , an effect size ( ES ) has been applied to evaluate differences among the
dementia groups while the healthy older
adults were used as a reference group . -
pubmed
Transcriptome and clinical survival information of
HCC patients was obtained from The Cancer Genome Atlas database . -
pubmed
Overall , a novel nomogram to predict the 1 - year and 3 - year OS of
HCC patients was developed , which shows good reliability and accuracy , for use in improved treatment decision - making . -
pubmed
In vivo studies indicated that the labeled platelets accumulated at the
plague of
atherosclerotic rabbits . -
pubmed
However ,
postmortem changes could not account for the large differences observed in the levels of
GHB found in
bovine caudate and those found in
guinea - pig ,
monkey and
human caudate . -
pubmed
Delayed
type hypersensitivity to
Staphylococcus aureus peptidoglycan in
guinea pigs . -
pubmed
Skin hypersensitivity to
Staphylococcus aureus peptidoglycan in
guinea pigs was studied . -
pubmed
Nonsensitized
guinea pigs and animals sensitized with emulsion of 1 mg or 100 microgram of peptidoglycan with complete or incomplete FREUND 's adjuvant exhibited distinct immediate
skin hypersensitivity . -
pubmed
After inoculation of healthy
guinea pigs with a live culture , the number of monocytes doubles and remains at this level up to the 11th day after the
infection . -
pubmed
A venal injection of
Salmonella abortus ovis allergen to sensibilized
guinea pigs , possessing a dermal -
allergic reaction , leads to a marked decrease in the number of monocytes in the blood on the 2nd and 6th hrs after application of the allergen , while on the 24th h their number regains the level prior injection . -
pubmed
Malformed spermatids and spermatozoa in the testes , epididymes , and ejaculates of 29 apparently healthy men and in 171
patients suffering from different
andrological diseases were investigated with the
electron microscope . -
pubmed
Reevaluation of the plasticity in the
rat supraoptic nucleus after chronic
dehydration using immunogold for
oxytocin and
vasopressin at the ultrastructural level . -
pubmed
Intrapapillary linear collections of
contrast medium ( ie , three or more linear collections of contrast material within a papilla ) were found in 10 ( 9.5 % ) of the 105
patients with
renal stone disease and two ( 1.0 % ) of the 195
patients without
nephrolithiasis ( P less than .001 ) . -
pubmed
Effects of
nifedipine versus
hydralazine on sympathetic activity and cardiac function in
patients with
hypertension persisting on diuretic plus beta - blocker therapy . -
pubmed
In
patients with
hypertension persisting on combined diuretic and beta - blocker therapy , the effects of an additional 9 - week therapy with a
calcium antagonist (
nifedipine ) versus a classical arterial vasodilator (
hydralazine ) were compared for changes in blood pressure ( BP ) , plasma
catecholamines ( n = 15 ) , and left ventricular ( LV ) systolic and diastolic function ( n = 6 ) . -
pubmed
Of 34
patients with apparently isolated
cerebellar lesions , postoperative outcome was good in 79 % . -
pubmed
Twelve ( 23 % ) of the
patients definitely had
von Hippel - Lindau disease (
VHLD ) . -
pubmed
All
patients with an apparently isolated
CNS haemangioblastoma should be investigated for evidence of
von Hippel - Lindau disease . -
pubmed
The patient had
infectious polyarthritis caused by
Haemophilus influenzae , which is a very rare cause of acute
polyarthritis in children older than 2 years . -
pubmed
In 265
patients of
acute myocardial infarction (
AMI )
heparin followed by
warfarin sodium was used routinely whenever there was no contraindication to the drug . -
pubmed
Another 265
patients of
AMI having identical clinical profiles were taken as control and neither any anticoagulant nor any antiplatelet agent was used in them . -
pubmed
One
patient developed
sternal dehiscence ;
wound complications or incompatibility with the suture material did not occur . -
pubmed
Isoprinosine enhances PHA responses and has potential effect on natural killer cell ( NK ) activity of
uremic patients in vitro . -
pubmed
We studied the effect of an immuno - stimulating agent ,
isoprinosine , which is being marketed as an antiviral drug , on some immune functions in vitro in 14
uremic patients treated by hemodialysis and in 10 healthy controls . -
pubmed
Our results motivate a clinical study with
isoprinosine in
uremic patients at the risk of
virus infection . -
pubmed
A single dose of the DNA - binding cytostatic agent
bleomycin ( 100 micrograms / g
body weight , subcutaneously ) was given to 10 - day - old
rats to study unscheduled repair DNA synthesis in nucleolar and in bulk nuclear chromatin of postmitotic Purkinje neurons . -
pubmed
The greatest benefit is realized in
patients treated within the first few hours of onset of
acute myocardial infarction . -
pubmed
All previous
patients with metastatic
Merkel cell carcinoma to the brain died within two months of the diagnosis . -
pubmed
We use this case to discuss possible routes of metastatic dissemination and to review the treatment options in
patients with distant
metastatic disease . -
pubmed
To our knowledge , this is the first reported case of presumed choroidal
metastasis of
Merkel cell carcinoma and the longest documented survival in a
patient with brain involvement . -
pubmed
The case history of a 41 - year - old
man with a
hibernoma in the scapular area is presented . -
pubmed
We have utilized DNA transfer and recombinant DNA techniques to probe DNA double - strand break repair in the
human ionizing radiation - sensitive
genetic syndrome ataxia - telangiectasia (
A - T ) . -
pubmed
Effects of
clofibrate on
hyperlipidemia induced by
polychlorinated biphenyls and elimination of
polychlorinated biphenyls accumulated in
rat tissues . -
pubmed
Our culture system may be useful in investigating the direct effects produced on
human trabecular meshwork by photocoagulation and various agents , for example anti -
glaucoma drugs ,
steroids and viscoelastic materials . -
pubmed
All
strains of staphylococci ,
streptococci ,
enterococci and
Listeria monocytogenes were inhibited at concentrations less than or equal to 2 micrograms / ml . -
pubmed
The myoelectrical activity of the large intestine of fed and fasted
rats was recorded with chronically implanted nichrome wire electrodes after destruction of the spinal cord , after
spinal cord transection , and after spinal anaesthesia . -
pubmed
The effect of training procedures on fixed - interval responding following
septal lesions in
rats . -
pubmed
Two experiments were conducted to assess the effects of training procedures on fixed - interval ( FI ) performance of
rats with
septal lesions . -
pubmed
The results suggest that
septal lesions result in a transient disruption in the FI performance of
rats with previous FI experience without affecting the acquisition of appropriate FI behavior . -
pubmed
Mesenteric
adenitis was diagnosed histologically in three patients and
Y. - pubmed
Possible application to problems of
human genetic disease are indicated . -
pubmed
Camping rewarding for
diabetic children . -
pubmed
Furthermore , experimental studies suggest that the growth of
signet - ring cell carcinoma transplanted on
nude mice depends on sex hormone . -
pubmed
Based on these observations , the clinical trial of chemo - endocrine therapy after gastrectomy for female
patients with diffuse
carcinoma of the stomach has been performed in our hospital since 1980 . -
pubmed
This result suggests that the chemo - endocrine therapy after gastrectomy may be a new hopeful adjuvant in female
patients with diffuse
carcinoma of the stomach . -
pubmed
The vector and soil transmitted
parasitic infections produce a highly diverse group of diseases in terms of the importance of their impact upon
human populations and in terms of the control methods that might limit that impact . -
pubmed
Twenty - seven
patients with
angina pectoris , 24 with
postmyocardial infarction angina and 7 with normal coronary arteries were examined by exercise
thallium-201 emission computed tomography ( SPECT ) and planar scintigraphy . -
pubmed
A
patient was referred for investigation of heavy
bleeding after surgery . -
pubmed
We studied the clinicopathologic and neuro - ophthalmic manifestations of
central nervous system toxoplasmosis in two
patients who were being treated with immunosuppressive chemotherapy , one for renal transplantation and the other for
systemic lupus erythematosis . -
pubmed
Although immune complexes are detectable in a high percentage of
bullous pemphigoid patients , their role in this disease may be epiphenomenal rather than pathogenetic , merely reflecting the presence of autoantibody and soluble
antigen . -
pubmed
Myocardial ischemia in
dogs with
gastric dilatation - volvulus . -
pubmed
The records of 10
patients with
cavernous choroidal hemangiomas were reviewed . -
pubmed
In contrast to the originally described
patient , who had a severe
hemorrhagic diathesis , our proband had only a mild
bleeding tendency . -
pubmed
Intracardiac and/or transesophageal electrophysiological studies were performed on seven
infants ( group 1 , mean age 2 months ) and four
children ( group 2 , mean age 9 y ; study 1 ) , and documented orthodromic
atrioventricular tachycardia in all cases . -
pubmed
The structure of this 190 - residue domain , which was expressed in and isolated from
Escherichia coli , is essentially identical to the structure of the catalytic domain within whole
diphtheria toxin determined at pH 7.5 . -
pubmed
Is it worth doing
barium enemas on
patients with unexplained
iron deficiency anaemia ? -
pubmed
The incidence on double contrast
barium enema ( DCBE ) of
carcinomas and
polyps & gt ; 1 cm in size was compared in 92
patients with
iron deficiency anaemia and a group of randomly obtained non - anaemic controls . -
pubmed
During
hemorrhage ,
DPSPX treatment significantly increased PRA levels ( P & lt ; .039 ) in
rats with intact kidneys . -
pubmed
DMPA has been tested in short- and long - term
toxicity studies in
rodents ,
rabbits , and
monkeys . -
pubmed
In addition ,
human IL-8 - R mRNA could be detected for the first time in
human melanoma cells . -
pubmed
Flocculent
strains of brewing
yeast grow and ferment as single cells and flocculate in the stationary phase of growth . -
pubmed
The presence of
carbohydrate receptors , outer - chain mannan side - branches , was monitored throughout growth of flocculent and non - flocculent
strains of
Saccharomyces cerevisiae , with particular attention to the growth phases where flocculation is normally developed . -
pubmed
While considerable variation was found in coflocculation and concanavalin A aggregation between
strains , little or no change in receptor availability was found throughout the growth of all
yeast strains . -
pubmed
The patient , a 65 - year - old
man , fell into
shock , due to acute
myocardial infarction and received cardiopulmonary resuscitation at home immediately . -
pubmed
These results taken together indicate that
swine may be a good
animal model for
human Ad5 lung infection to aid in the evaluation of candidate
adenovirus vaccines and that
Ad5 may be suitable as a recombinant viral vaccine or for other applications in
swine . -
pubmed
Oral contraceptive agents are not contraindicated in
women with
epilepsy ; however , the contraceptive failure rate increases fourfold if
patients are being treated concurrently with enzyme - inducing antiepileptic drugs . -
pubmed
The dosage should be adjusted if the
patient 's
seizures are increasing . -
pubmed
Women with
epilepsy may have disease - related or treatment - related
menstrual dysfunction , complications of pregnancy ( slightly increased risk of
toxemia and
fetal loss ) ,
endocrine dysfunction , appearance changes ( a general coarsening of facial features with long - term administration of antiepileptic agents ) , and psychosocial maladjustment . -
pubmed
Although control of
seizures remains the primary goal of treating
women with
epilepsy , the widening choice of antiepileptic drugs may facilitate optimal management of secondary and gender - specific complications . -
pubmed
Phenotypic and genotypic characterization of spotted
fever group Rickettsiae isolated from
Catalan Rhipicephalus sanguineus ticks . -
pubmed
Eighty - nine
Rhipicephalus sanguineus ticks and 21
Rhipicephalus bursa ticks collected in Catalonia were tested by the hemolymph test to establish their
infection rate with spotted
fever group rickettsiae . -
pubmed
PCR followed by restriction fragment length polymorphism analysis showed that the six
strains were identical and were characterized by the same restriction profiles as a
strain , Mtu5 , previously isolated from
Rhipicephalus turanicus ticks in the South of France . -
pubmed
Phylogenetic analysis showed that this new rickettsial sero- and genotype , which will be named the " Catalan
strain , " is closely related to
Rickettsia massiliae . -
pubmed
We successfully performed a total correction which consisted of a resection of the intra - left atrial fibrous membrane , reconstruction of the LSVC return pathway to the right atrium with PTFE graft , atrial partition with a
bovine pericardial patch and the conotruncal repair for
Tetralogy of Fallot . -
pubmed
We have reviewed the clinical documentation of all the
patient aged 65 or more admitted to our hospital because of recent onset typical or
atypical angina , who underwent an exercise tolerance test and coronary angiography . -
pubmed
At coronary angiography 6
patients showed non obstructive lesions ( range : 20 - 40 % ) and only 5 had normal findings : 2 of these patients showed
gastro - intestinal disease which could be considered as possible trigger of
chest pain . -
pubmed
We conclude that
syndrome X may appear also in the elderly with the same clinical features already described in younger
patients . -
pubmed
The
toxicity of G28 - 5 sFv - PE40 was examined in
SCID mice ,
rats , and
monkeys , with the maximum tolerated dose being 0.48 , 1.0 , and 1.67 mg / kg , respectively . -
pubmed
Although transgenic proteins accumulated in low amounts in all the plant lines analysed , accumulation of the mutant non - processed protein form was greatly increased in plants following
infection with TEV , but not
TMV , apparently as a consequence of protein stabilization . -
pubmed
All
patients had metastatic disease within cervical lymph nodes at presentation and eventually developed distant
metastases . -
pubmed
Pneumolysin - deficient mutant strains of
Streptococcus pneumoniae are known to cause less - severe
sepsis than wild - type
pneumococcal strains that produce pneumolysin . -
pubmed
This difference is associated with greater host resistance in
mice infected with the pneumolysin - deficient
strains . -
pubmed
The concentrations of S , B ,
Al ,
Cr ,
Fe ,
Si ,
Ti , and
Zn correlated with
injury in cell membranes of
R. - pubmed
Multivariate logistic regression analyses showed that presence of anti -
HCV , male gender , and history of
liver disease were associated with the presence of
liver dysfunction , and that age of more than 40 years and a particular district were associated with the presence of anti -
HCV . -
pubmed
The incidence of
liver dysfunction was significantly higher in
HCV RNA - positive men than women ( 32 , or 66.7 % versus 22 , or 30.6 % ) ( P & lt ; 0.05 ) . -
pubmed
These findings suggest that : ( 1 )
HCV was correlated with the high mortality rate from
liver diseases , ( 2 ) there were district - related differences in the incidence of
HCV , and ( 3 ) the lower frequency of elimination of
HCV from men may explain why they showed a high mortality from
liver disease . -
pubmed
[ Increasing the efficacy of treating
patients with extensive
ovarian cancer by using
laferon ] . -
pubmed
Patients with
stage III - IV cancer of the ovary have been shown to derive a greater benefit from conventional complex treatments involving adjuvant
laferon therapy . -
pubmed
Signs of
glaucoma in
rhesus monkeys from a restricted gene pool . -
pubmed
The aetiologic agent of
avian colibacillosis is
Escherichia coli . -
pubmed
Colibacillosis is a disease that causes mortality and production performance problems in
chickens which results in economic losses for the poultry industry . -
pubmed
In the battery study , subcutaneous administration of LPS to one - day - old
broiler cockerels caused a significant reduction ( P & lt ; 0.003 ) in all parameters of
colibacillosis evaluated , i.e. -
pubmed
However , in the floor - pen study , subcutaneous administration to one - day - old
broiler chicks resulted in a numerical , but not statistically significant reduction ( P & lt ; 0.1 ) in mortality associated with
colibacillosis . -
pubmed
Favorable combination effects of the
leukotriene synthesis inhibitor
BAY X 1005 and
dexamethasone on
edema formation in the
arachidonic acid - induced
mouse ear inflammation test . -
pubmed
The effects of a combination of the
leukotriene synthesis inhibitor ( LSI )
BAY X 1005 with the glucocorticosteroid
dexamethasone were studied in the
arachidonic acid ( AA)-induced
mouse ear
inflammation test ( AA - MEIT ) . -
pubmed
Sildenafil for women
patients with antidepressant - induced
sexual dysfunction . -
pubmed
In an open study ,
sildenafil (
Viagra ) was prescribed for nine
women outpatients who reported
sexual dysfunction induced by antidepressant medication , primarily selective
serotonin reuptake inhibitors . -
pubmed
The nine
patients , all of whom had experienced either
anorgasmia or
delayed orgasm with or without associated disturbances , reported significant reversal of
sexual dysfunction , usually with the first dose of 50 mg of
sildenafil . -
pubmed
We herein report two
patients with left
atrial myxoma who needed an emergency operation . -
pubmed
Case 1 was a 48 - year - old
woman who was injured in a traffic accident and underwent an operation for a right leg
fracture . -
pubmed
MATERIALS AND METHODS : Two hundred eighty - one
patients underwent 306 sonographically guided compression procedures on 297
groin pseudoaneurysms after femoral artery catheterization . -
pubmed
The medical records , cardiac catheterization reports , and sonographic images were reviewed to determine
patient demographics , type of catheterization procedure performed , sheath size , access site , interval from sheath removal to compression , anticoagulation status ,
pseudoaneurysm dimensions , complications , and follow - up information . -
pubmed
Eleven complications ( 3.6 % ) occurred , including three
patients with
rupture during compression . -
pubmed
CASE DESCRIPTION : A 63 - year - old
woman presented with left putaminal
hemorrhage . -
pubmed
diphtheriae
strains of biovar gravis ,
ribotype M11 , dominated in the 40 - 60 years and
C. - pubmed
All
patients admitted to the coronary care unit with suspected
acute coronary syndromes were evaluated by serial electrocardiography and blood draws on admission and at 4 and 12h from admission . -
pubmed
These data will be used for future studies of differential protein expression in
mouse models of
neurological disorders . -
pubmed
RESULTS : We showed previously that wild - type
mice developed a mild form of
EAE with complete recovery . -
pubmed
We also induced
EAE by passive transfer of MOG(35 - 55)-reactive lymph node cells , and this disease was aggravated by sympathectomy in both wild - type and knockout
animals . -
pubmed
To study the effect of chemotherapy on bone marrow angiogenesis in
patients with
multiple myeloma , we used two methods to evaluate bone marrow angiogenesis in
patients with newly diagnosed
multiple myeloma , comparing these findings with those from bone marrow obtained after standard chemotherapy . -
pubmed
We conclude that the degree of bone marrow angiogenesis is a prognostic marker in
patients with
multiple myeloma and does not decrease significantly after therapy . -
pubmed
[ Therapy of
fractures of the thigh in
children ] . -
pubmed
Isolation of crystalline
aldosterone from the urine of a
child with the
nephrotic syndrome . -
pubmed
Essential hypertension in
humans may develop through a combination of genetic and environmental factors . -
pubmed
During
mammalian fertilization , sperm adhere to the extracellular coat of the egg , or
zona pellucida , in a species - specific manner . -
pubmed
In conclusion , this model provides a robust economic analysis of the cost of
lung cancer management , and will be useful for assessing the economic consequences of future changes in
patient management . -
pubmed
Acupuncture was used to treat a 69 - year - old
man for bilateral
ankle pain related to his
rheumatoid arthritis . -
pubmed
RESULTS : Eleven ( 27 % ) of the
patients with type A
hematoma and 1 ( 2 % ) of the
patients with type B
hematoma underwent early surgical intervention . -
pubmed
Others were treated medically , and the overall hospital mortality was 7 % for
patients with type versus 2 % for
patients with type B intramural
hematomas of the aorta ( P = .315 ) . -
pubmed
Twenty - three
patients , 9 ( 22 % ) with type A and 14 ( 26 % ) with type B intramural
hematomas of the aorta , underwent late surgical intervention during the follow - up period , and there were no hospital
deaths . -
pubmed
A total of 23
patients died during the follow - up period , including 6 of intramural
hematoma of the aorta - related
deaths ( 3 in the type A group and 3 in the type B group ) . -
pubmed
Tick - borne fever as a cause of
abortion in
sheep . -
pubmed
Physician should be alert to the occurrence of
hematogenous disseminated tuberculosis , especially in immune compromised
patients with long - term
fever and
systemic injury . -
pubmed
Patients , 50 - 89 years of age , with
hip fracture ( cases ) were ascertained through surveillance of 18 Utah hospitals during 1997 - 2001 . -
pubmed
A nano - view of
West Nile virus - induced cellular changes during
infection . -
pubmed
An understanding of the ecological factors that regulate natural populations of
Aedes aegypti mosquitoes can improve control and reduce the incidence of
dengue (
DF ) and
dengue hemorrhagic fever (
DHF ) in tropical areas . -
pubmed
We used
starvation resistance ( number of days alive without food ) as an indicator of the feeding history in third - instar
Ae . - pubmed
If resistance to
starvation and adult mass of field - collected
Ae . - pubmed
[
Pseudomonas aeruginosa meningitis in a 2 months old infant ] . -
pubmed
[ Influence of moderate
body weight excess on the nycthemeral pattern of blood pressure , renal function and
sodium and water excretion in
patients with essential
hypertension ] . -
pubmed
We studied the relationships between the
body mass index (
BMI ) and the nycthemeral pattern of blood pressure ( BP ) , renal function and
sodium and water excretion ( EX ) in a group of 25 moderately
hypertensive untreated
men ( 41 + /- 2 y , 80 + /- 3 kg ) . -
pubmed
The selective
serotonin reuptake inhibitors controversy in the treatment of
depression in
children . -
pubmed
BACKGROUND : Reperfusion before primary PCI in
patients with
ST - segment elevation myocardial infarction (
STEMI ) is associated with an improved outcome . -
pubmed
Hyperglycemia in
patients with
STEMI is associated with an adverse prognosis . -
pubmed
METHODS : A total of 460 consecutive
patients with
STEMI treated with primary PCI were included in this analysis . -
pubmed
RESULTS :
Hyperglycemia was observed in 70 % and TIMI flow grade 3 before primary PCI in 17 % of the
patients . -
pubmed
Patients with
hyperglycemia less often had TIMI flow grade 3 before primary PCI ( 12 % vs. 28 % , p & lt ; 0.001 ) . -
pubmed
CONCLUSIONS :
Hyperglycemia in
patients with
STEMI is an important predictor of impaired epicardial flow before reperfusion therapy has been initiated . -
pubmed
Despite the significant decline in the incidence of
acquired immune deficiency syndrome (
AIDS)-related
KS with the use of highly active antiretroviral therapy ( HAART ) , some
patients , even those with a good immune restoration , still have aggressive disease . -
pubmed
Nine
human immunodeficiency virus ( HIV )- infected patients were treated from 1997 to 2002 with
docetaxel . -
pubmed
Grade 4
neutropenia and
thrombocytopenia were observed in four of nine and one of nine
patients , respectively . -
pubmed
One
patient died after
sepsis . -
pubmed
CONCLUSIONS :
Docetaxel has a good and rapid efficacy in
anthracycline - pretreated
patients with severe
AIDS - related
KS . -
pubmed
Like
2 - hydroxy-1,4 - naphthoquinone , the
2 - amino - derivative was found to cause both
haemolytic anaemia and
renal tubular necrosis in
rats . -
pubmed
woesei may have acquired by lateral gene transfer more than 100 ORFs from other organisms living in the same thermophilic environment to produce the type
strain of
P. - pubmed
Although severe disease develops only in about 1 % of
infections ,
WNV has claimed a total of 564 lives in the 5 years from 1999 to 2003 . -
pubmed
Phylogenetic analysis of Brazilian
HIV type 1 subtype D
strains : tracing the origin of this subtype in Brazil . -
pubmed
HIV-1 Subtype D occurs mainly in East and Central African countries , especially Uganda , where the prevalence of
HIV-1 infection is among the highest in the world . -
pubmed
Sequences from an Angolan immigrant showed close genetic similarity with a
strain described in Finland , from an
HIV patient of African origin , whereas all four autochthonous Brazilian sequences clustered with South African
strains , where subtype D occurs only in isolated cases . -
pubmed
Our results suggest the successful introduction and circulation in Brazil of closely related
HIV-1 subtype D
strains , possibly of South African origin . -
pubmed
Cystic hydatic disease in
sheep : treatment with percutaneous aspiration and injection with
dipeptide methyl ester . -
pubmed
( 4 )
Aspirin and
sulindac were tested for the prevention of
polyps in
patients with
familial adenomatous polyposis , with uncertain results and weak evidence of effectiveness . -
pubmed
It involved 77
patients with
familial polyposis and colorectal
polyps , and 6 patients with only duodenal
polyps . -
pubmed
Community - acquired
necrotizing fasciitis due to
Pseudomonas aeruginosa . -
pubmed
Furthermore , DNA - DNA hybridization showed only 54 - 66 % DNA relatedness between the novel isolates and
strains of
B. - pubmed
The type
strain is
FO-36b(T ) (= ATCC BAA-1126(T)=NBRC 100820(T ) ) . -
pubmed
OBJECTIVE : To compare the appropriate screening for and the prevention and treatment of
osteopenia and
osteoporosis in transplant
patients before and after a bone health protocol was implemented . -
pubmed
The groups were well matched , with no statistically significant differences noted for any of the baseline characteristics that were compared , including the modifiable and nonmodifiable risk factors known to put a
patient at increased risk for
osteopenia or
osteoporosis . -
pubmed
Exotic
fungal infection in a
horse . -
pubmed
Compounds 9 and 24 were also tested as gamma/(gamma+beta ) mRNA inducers in erythroblasts obtained from
patients with beta(0 )
thalassemia . -
pubmed
Dysfunction of endothelial cells ( EC ) is known to promote abnormal vascular growth such as that in
atherosclerosis and
arteriosclerosis and has been postulated as an initial trigger of the progression of
atherosclerosis in
patients with
diabetes mellitus , and
hyperglycemia is an independent risk factor for the development of
cardiovascular disease . -
pubmed
A recent clinical trial suggested that
statins prevent several vascular events in
patients with
type 2 diabetes without a high concentration of LDL -
cholesterol . -
pubmed
These pleiotropic effects of
statins can be expected to improve
endothelial dysfunction through
nitric oxide production and/or an anti - oxidant effect in
diabetic patients . -
pubmed
We compared the clinical benefits of a 12 - month exercise intervention programme consisting of either brisk walking or a medical fitness programme in
type 2 diabetes patients . -
pubmed
METHODS : We randomised 92
type 2 diabetes patients ( 60 + /- 9 years old ) to either three times a week of 60 min brisk walking ( n = 49 ) or medical fitness programme ( n = 43 ) . -
pubmed
BACKGROUND :
Human parechoviruses (
HPeVs ) have been associated with severe conditions such as
neonatal sepsis and
meningitis in young children . -
pubmed
CONCLUSIONS : These results suggest that
HPeV screening of paediatric clinical samples should be included in viral diagnostics in suspected cases of
neonatal sepsis and
meningitis . -
pubmed
METHODS : From April 2005 to August 2006 , 26 cases ( 30 sides ) of
alveolar cleft were treated with trabecular substance of self - ilium combined with the decalcified dentinal matrix of
human ( DDM ) . -
pubmed
RESULTS : Twenty - three
patients achieved healing by first intention ,
oronasal fistulas were closed successfully . -
pubmed
RATIONALE :
Malnutrition in hospitals is often not assessed and malnourished
patients rarely receive specific nutritional therapy . -
pubmed
Twenty - two
depressed mothers of psychiatrically ill
children were recruited from a larger clinical trial ; half were randomly assigned to receive an adapted form of interpersonal psychotherapy ( IPT - MOMS ) , while the other half received treatment as usual ( TAU ) . -
pubmed
The effect of subcutaneous injections of
benzoquinone on
Staphylococcus aureus infection of the
bovine mammary gland . -
pubmed
Following autologous transplant and engraftment , 30
patients ( 35.7 % ) had a transient secondary decline in their plt counts , which was not associated with graft rejection ,
relapse or
infection . -
pubmed
One
patient had a previous ceramic implantation and the other a large
titanium mesh , whose precedent local skin flap methods to treat the
scalp ulcer were not successful . -
pubmed
METHODS : Thirty - eight lesions from 37
patients with
angina pectoris who demonstrated & gt;70 %
coronary stenosis on multislice computed tomography were evaluated by noncontrast T1WI using a 1.5 - T magnetic resonance imager , and 25 lesions were evaluated by intravascular ultrasound . -
pubmed
Noncontrast T1WI in cardiac magnetic resonance imaging may be useful for the assessment of
coronary plaque characterization in
patients with
coronary artery disease . -
pubmed
Long - term flaxseed oil supplementation diet protects BALB / c
mice against
Streptococcus pneumoniae infection . -
pubmed
pneumoniae D39
serotype 2 infection in
mice . -
pubmed
Moderate
pneumonia was observed in supplemented , infected
mice compared to severe
pneumonia seen in control
mice . -
pubmed
[
Vein thromboembolism prevention in
stroke patients ] . -
pubmed
VENOUS THROMBOEMBOLISM PREVENTION IN
STROKE : The high incidence of
deep vein thrombosis ( 30 % clinically and up to 50 % subclinically ) in acute
stroke hemiparetic and bed ridden
patients within two weeks from the onset and 1 - 2 %
pulmonary embolism with the fatal outcome in the first month clinically and 17 % of all fatal outcomes in postmortem investigations present a necessity for the early
venous thromboembolism prevention . -
pubmed
On the other hand , the most powerful prevention strategy -- anticoagulation has important limitations in
acute stroke patients : almost impossible to be used in
cerebral haemorrhage and a great risk for the development of
haemorrhagic transformation in
cerebral infarction . -
pubmed
CONCLUSION :
Venous thromboembolism prevention in
stroke patients is necessary because of a greater risk for
venous thromboembolism in these
patients according to the nature of illness and
functional disability , but also a problem because of limited possibility to recommend the proper medicament according to the risk of serious complications . -
pubmed
The necessity of preventing
venous thromboembolism and estimation of effectivity - risk ratio in
stroke patients , beside plenty of studies and consensus conferences , remain individual and often very difficult . -
pubmed
As the result of improved bacteriological techniques ,
Kingella kingae is a slow - growing Gram - negative coccobacillus that is emerging as an important cause of
spondylodiscitis in children younger than 3 years of age . -
pubmed
A 64 - year - old
woman presented with right
hip pain of 6 years ' duration , accompanied by limping of 1 years ' duration . -
pubmed
Therefore , caution should be taken with administration of anticoagulant therapy in
patients with massive
hemorrhage , especially in
patients with continuous
low blood pressure . -
pubmed
A gram - positive and aerobic bacterium , designated
strain YIM 49065 ( T ) , was isolated from rhizospheric soil of
Jatropha curcas in Yunnan , China . -
pubmed
Furthermore , DNA - DNA hybridizations among
strains YIM 49065 ( T ) ,
I. - pubmed
, for
strain YIM 49065 ( T ) ( = DSM 23217(T ) = CCTCC AA 209077(T ) ) . -
pubmed
Lymphocytic choriomeningitis virus (
LCMV ) is a rare cause of
central nervous system disease in
humans . -
pubmed
ATP - Sensitive
Potassium Channel - Deficient
Mice Show
Hyperphagia but Are Resistant to
Obesity . -
pubmed
Baccharis trimera is a plant popularly used as a
tea and to treat
gastrointestinal diseases and inflammatory processes as well . -
pubmed
Coronary artery disease in elderly
women : a disturbed relation of
estrogen with
testosterone . -
pubmed
A pattern of high phagocytosis , consumption of classical pathway components , and a broad anti - H ab repertoire was seen particularly in
patients with
nephritis and
serositis . -
pubmed
Management of
factor VII - deficient patients undergoing joint surgeries -- preliminary results of locally developed treatment regimen . -
pubmed
Preliminary results demonstrate that rFVIIa administered according to our treatment regimen is an effective and safe haemostatic agent for
hypoproconvertinaemia patients undergoing orthopaedic surgery . -
pubmed
: METHODS : A multicenter , consecutive case series of
patients with biopsy - proven conjunctival , orbit , eyelid , or
lacrimal gland / sac lymphoma was performed . -
pubmed
The effects of different
dobutamine infusion rates on hypercapnic
depression of diaphragmatic contractility in
pentobarbital - anesthetized
dogs . -
pubmed
A tissue array was constructed comprising 63
EOC patients . -
pubmed
Type 2 diabetes was induced in overnight fasted
Sprague Dawley rats pre - treated with
nicotinamide ( 100 mg / kg , i.p . ) -
pubmed
The
rats were divided into ; I - nondiabetic , II -
diabetic control , III -
sitagliptin ( 5 mg / kg , p.o . ) -
pubmed
A single - dose extended -
toxicity study for NOTA-2Rs15d was performed on healthy
mice up to a dose of 10 mg / kg . -
pubmed
An analysis of cervical spine magnetic resonance imaging findings after normal computed tomographic imaging findings in pediatric
trauma patients : ten - year experience of a level I pediatric
trauma center . -
pubmed
BACKGROUND : A variety of radiologic screening protocols exist for evaluation of pediatric
trauma patients with potential cervical spine ( c - spine )
injuries . -
pubmed
METHODS : A retrospective chart review of
trauma patients evaluated at Rady Children 's Hospital , San Diego , between January 2000 and February 2010 was conducted . -
pubmed
Trauma patients who were younger than 18 years , placed in c - spine precautions , had a normal c - spine CT scan , who subsequently had a c - spine MRI were included . -
pubmed
CONCLUSION : Our results suggest that high - resolution CT scan with sagittal and coronal reconstructions may be comparable with MRI for the detection of unstable c - spine
injuries in pediatric
trauma patients . -
pubmed
Autologous
rabbit adipose tissue - derived mesenchymal stromal cells for the treatment of
bone injuries with distraction osteogenesis . -
pubmed
METHODS :
Bone defects were produced in the tibias of New Zealand
rabbits that had previously undergone adipose tissue extraction . -
pubmed
MATERIAL AND METHODS : Histology in 53
IgAN patients ( M / F 35/18 age 40.5 years ( 17 - 65 ) ) was evaluated using the Oxford classification system . -
pubmed
We report a series of 14
patients with
multiple myeloma or
NHL successfully mobilized and harvested by
plerixafor together with large - volume leukaphereses ( LVL ) . -
pubmed
The failure of nonleukopenic doses of
colchicine to suppress
urate crystal - induced
canine joint
inflammation . -
pubmed
Colchicine suppressed the development of
urate crystal - induced
canine synovitis only at a dose ( 0.25 mg / kg ) that produced a
peripheral leukopenia ; half that amount produced neither
leukopenia nor inhibition of the inflammatory response . -
pubmed
The
canine model differs from
human gouty inflammation and from
urate crystal - induced
human inflammation , both of which processes respond to small , nonleukopenic doses of
colchicine . -
pubmed
In
patients with suspected
IgG4 - RD and skin changes , skin biopsy may serve as a diagnostic screen or to supplement nondiagnostic visceral biopsy specimens . -
pubmed
MATERIALS AND METHODS : A total of 20 enamel samples of
human molar teeth were subjected to artificial
caries lesion formation using pH cycling method and was verified using high resolution scanning electron microscope ( HRSEM ) . -
pubmed
Carvedilol ameliorates early
diabetic nephropathy in
streptozotocin - induced
diabetic rats . -
pubmed
The aim of this study therefore is to evaluate the possible protective effect of
carvedilol on
streptozotocin - induced early
diabetic nephropathy and various mechanisms underlie this effect in
rats . -
pubmed
injection of
streptozotocin ( 65 mg / kg ) was administered to induce early
diabetic nephropathy in
Wistar rats . -
pubmed
In conclusion ,
carvedilol protects
rats against
streptozotocin - induced early
diabetic nephropathy possibly , in part , through its antioxidant as well as anti - inflammatory activities , and ameliorating podocyte
injury . -
pubmed
The cardiovascular autonomic imbalance in
patients after
myocardial infarction (
MI ) provides a significant increase in mortality rate , and seems to precede metabolic , hormonal , and immunological changes . -
pubmed
Common dysregulation network in the
human prefrontal cortex underlies two
neurodegenerative diseases . -
pubmed
Using expression profiles from postmortem prefrontal cortex samples of 624
dementia patients and non - demented controls , we investigated global disruptions in the co - regulation of genes in two
neurodegenerative diseases , late - onset
Alzheimer ' s disease (
AD ) and
Huntington ' s disease (
HD ) . -
pubmed
We identified networks of differentially co - expressed ( DC ) gene pairs that either gained or lost correlation in disease cases relative to the control group , with the former dominant for both
AD and
HD and both patterns replicating in independent
human cohorts of
AD and aging . -
pubmed
CONCLUSIONS :
Patients supported with extracorporeal membrane oxygenation were exposed to large RBC transfusion volumes for treatment of mild
anemia resulting from
blood loss , particularly phlebotomy . -
pubmed
Within the light of recent WHO recommendations for
Bacillus thuringiensis israelensis (
Bti ) use against
malaria and other vector species , larval source management could see a revival in the upcoming years . -
pubmed
We postulated that
human inter -
seizure intervals would follow a power - law relationship , and furthermore that evidence for the existence of a long - memory process could be established in this relationship . -
pubmed
Our results provide evidence that companion animals like dogs may be
MRS carriers , and that continued surveillance of
MRS in companion animals is required to prevent increased incidences in
humans . -
pubmed
An internal inclusivity validation demonstrated detection of all 50 tested
strains of
. - pubmed
1,4 - BQ demonstrated concentration - dependent
cytotoxicity in
mouse BM cells . -
pubmed
Taken together ,
1,4 - BQ caused lineage - related
cytotoxicity in
mouse HPCs , demonstrating greater toxicity in single - lineage progenitors than in those of multi - lineage . -
pubmed
Diffusion in the corpus callosum in
patients with early
schizophrenia . -
pubmed
Diffusion in the cerebral corpus callosum in
patients with
early schizophrenia was studied by diffusion tensor MRT and magnetic resonance spectroscopy . -
pubmed
Further research is needed to discern clear mechanisms and to help efforts to counteract
muscle weakness and
exercise intolerance in
uremic patients . -
pubmed
Chryseobacterium indologenes in four patients with
leukemia . -
pubmed
Chryseobacterium indologenes is a rare opportunistic pathogen causing
hospital - acquired infection . -
pubmed
Two of the patients , undergoing peripheral blood allogeneic hematopoietic stem cell transplantation ( alloHSCT ) from
human leukocyte antigen - identical sibling donors , died of
pneumonia caused by
C. - pubmed
Blood infection with
C. - pubmed
CONCLUSION : The quality of care for
febrile neutropenia in
patients presenting through the ED was comparable to those directly admitted to the hospital in this 2 - center study . -
pubmed
The effects of
DL-3 - n - butylphthalide in
patients with
vascular cognitive impairment without
dementia caused by subcortical
ischemic small vessel disease : A multicentre , randomized , double - blind , placebo - controlled trial . -
pubmed
METHODS : In this randomized , double - blind , placebo - controlled trial , we enrolled
patients aged 50 - 70 years who had a diagnosis of
subcortical Vascular cognitive impairment without
dementia at 15 academic medical centers in China . -
pubmed
DISCUSSION : Over the 6 - month treatment period ,
NBP was effective for improving cognitive and global functioning in
patients with subcortical
vascular cognitive impairment without
dementia and exhibited good safety . -
pubmed
CONCLUSIONS : Since massive transfusion provokes further problems in
patients who are already severely traumatized and
anaemic , once this course of action has been decided upon , a profound knowledge of its potential complications , careful monitoring and proper follow - up are all essential . -
pubmed
The antiproliferative activity of two chito - specific agglutinins purified from
Benincasa hispida ( BhL ) and
Datura innoxia ( DiL9 ) of different
plant family origin was investigated on various
cancer cell lines . -
pubmed
PURPOSE : To evaluate differences in measurements of macular pigment optical density ( MPOD ) in
patients with dry age - related
macular degeneration (
AMD ) and a group of healthy
patients ( control group ) . -
pubmed
METHODS : This cross - sectional study included 31 eyes from 31
patients with bilateral
dry AMD , 21 eyes from 21
cases with
dry AMD in the study eye and
exudative AMD in the fellow eye . -
pubmed
A randomised , double - blinded , placebo - controlled clinical study on intra - articular hyaluronan treatment in
equine lameness originating from the metacarpophalangeal joint . -
pubmed
BACKGROUND :
Intra - articular inflammation resulting in
lameness is a common health problem in
horses . -
pubmed
Exogenous intra - articular
hyaluronic acid has been shown to provide an analgesic effect and reduce
pain in
equine and
human osteoarthritis . -
pubmed
High molecular weight non -
animal stabilized
hyaluronic acid ( NASHA ) has gained popularity in the treatment of
human arthritic conditions due to its long - acting
pain - relieving effects . -
pubmed
The aim of this study was to compare the response to treatment of
lameness localized in the
equine metacarpophalangeal joint injected with non -
animal stabilized
hyaluronic acid ( NASHA ) and placebo ( saline ) . -
pubmed
CONCLUSIONS : In the present study , a single IA NASHA injection was not better than a single saline injection for reducing
lameness in
horses with
synovitis or mild
osteoarthritis . -
pubmed
On - going research is attempting to use amphibian symbiotic bacteria to develop probiotic treatments that can protect hosts from the causative agent of
chytridiomycosis , the fungal pathogen
Batrachochytrium dendrobatidis . -
pubmed
Giraffe skin disease (
GSD ) is a disorder of undetermined etiology that causes lesions on the forelimbs of
Masai giraffe (
Giraffa camelopardalis tippelskirchi ) . -
pubmed
AIMS : Hip resurfacing arthroplasty ( HRA ) is an alternative to conventional total hip arthroplasty for
patients with
osteonecrosis (
ON ) of the femoral head . -
pubmed
PATIENTS AND METHODS : Long - term survivorship , clinical scores and radiographic results for 82
patients ( 99 hips ) treated with HRA for
ON over a period of 18 years were reviewed retrospectively . -
pubmed
Patients were resurfaced regardless of the size of the
osteonecrotic lesion . -
pubmed
Erlotinib has comparable clinical efficacy to chemotherapy in pretreated
patients with advanced
non - small cell lung cancer (
NSCLC ): A propensity - adjusted , outcomes research - based study . -
pubmed
MATERIALS AND METHODS : We included
patients with advanced
NSCLC receiving at least two lines of palliative systemic treatment between January 2005 and December 2014 and not harbouring targetable driver mutations . -
pubmed
CONCLUSION : The present study suggests
erlotinib to have similar clinical efficacy compared to chemotherapy in
patients with pretreated advanced
NSCLC and no known molecular targetable alterations . -
pubmed
Burkholderia pseudomallei , the causative agent of a fatal disease
melioidosis , is one such biothreat agent whose differentiation from its near - neighbor species is always a challenge . -
pubmed
OBJECTIVE : Exposure to maternal
depression across the first years of life markedly increases
children 's susceptibility to psychopathology , yet no study has tested its effects on the maturation of children 's social brain . -
pubmed
Children of mothers with
depression showed enhanced alpha rebound to
pain in the right posterior superior temporal gyrus , which was unrelated to emotion detection abilities , pointing to decreased late processing of others ' overwhelming experiences in socio - cognitive areas . -
pubmed
CONCLUSION : These findings , from the first study to examine maternal
depression and early caregiving as long - term predictors of
children 's neural empathic response , pinpoint a decrease in top - down socio - cognitive mechanisms as potential pathways for the cross - generational transfer of vulnerability from mothers with
depression to their offspring and highlight the need for early interventions focused on enhancing maternal attunement . -
pubmed
Unlike most other lesions in
patients with unstable symptoms , where coronary intervention with stenting is recommended ,
patients with
SCAD generally fare better with conservative measures than with intervention , unless there is hemodynamic instability . -
pubmed
METHODS : Twenty - three LV tissue samples were obtained from
ICM patients ( n=13 ) undergoing heart transplantation and control donors ( n=10 ) for RNA sequencing analysis . -
pubmed
Patients can be at risk of angle - closure
glaucoma in this condition , and traditional methods of angle assessment can be subjective and difficult to perform in the
inflamed eye . -
pubmed
OBJECTIVE :
Obesity variably disrupts
human health , but molecular - based
patients ' health - risk stratification is limited . -
pubmed
Adipose tissue ( AT ) stresses may link
obesity with
metabolic dysfunction , but how they signal in
humans remains poorly - characterized . -
pubmed
MATERIALS AND METHODS : The data of 186
patients aged & gt;80 years with
colorectal cancer were collected from a computer database , and the variables were analyzed by both uni- and multivariate analyses . -
pubmed
CONCLUSIONS : After good surgical selection , low early mortality and acceptable long - term survival can be achieved even in the oldest old
patients with
colorectal cancer . -
pubmed
The first case was an 11 - month - old
boy presenting with complaints of recurrent
soft tissue infection ,
ear infection ,
anemia , and
thrombocytopenia with a low platelet volume . -
pubmed
MATERIALS AND METHODS : Seventeen term
neonates with moderate or severe
HIE underwent therapeutic
hypothermia . -
pubmed
Updates on early
peanut introduction and prevention of
peanut allergy . -
pubmed
We found many
patients with
LA and processed them appropriately . -
pubmed
RESULTS : The
wound of all
patients healed up . -
pubmed
Prospective Evaluation of Predictors of
Testis Atrophy After Surgery for
Testis Torsion in
Children . -
pubmed
METHODS :
Patients 2 months-18 years old with unilateral
acute scrotum were consecutively enrolled in a National Institutes of Health transcutaneous near - infrared spectroscopy study , with a subgroup analysis of the true
torsion group . -
pubmed
All
patients with a black or
hemorrhagic testis had & gt;80 % volume loss . -
pubmed
Simulated Microgravity Culture Enhances the Neuroprotective Effects of
Human Cranial Bone - Derived Mesenchymal Stem Cells in
Traumatic Brain Injury . -
pubmed
In this study , we investigated the therapeutic mechanisms of transplantation of cMSCs cultured under MG conditions in
traumatic brain injury (
TBI ) model
mice . -
pubmed
We found that the
cyp17a1 - deficient fish at 3 months postfertilization ( mpf ) were all fertile males with normal testis and spermatogenesis but compromised male - typical mating behaviors and secondary sex characters ( SSCs ) , including breeding tubercles , body pigmentation , and anal fin coloration . -
pubmed
This all - male phenotype of the
cyp17a1 - deficient fish could be restored with
testosterone or
estradiol treatment . -
pubmed
Arboviruses incorporate a vast collection of genetically diverse viral pathogens including that of
dengue ,
Zika and
chikungunya . -
pubmed
Case Report : A 22 - year - old
gentleman presented with ASIA
Aparaplegia following
road traffic accident . -
pubmed
The
patient also had
liver laceration . -
pubmed
The
toxicity of alphadelta - BgTx-1 ( LD50 = 0.17 - 0.28 microg / g
mouse , i.p . -
pubmed
Tai chi chuan exercises improve functional outcomes and quality of life in
patients with primary total knee arthroplasty due to
knee osteoarthritis . -
pubmed
A single - centre , single - blind , randomised controlled trial was designed to explore whether tai chi chuan ( TCC ) exercises can improve the functional outcomes and the quality of life ( QOL ) in
patients with primary TKA due to
knee osteoarthritis (
OA ) . -
pubmed
MATERIALS AND METHODS : One hundred seven
participants with primary TKA for end - stage
knee OA were enrolled from January 2014 to January 2017 . -
pubmed
This study aimed to explore ocular
Demodex infestation on the microstructure changes of the meibomian glands ( MGs ) in
patients with
MGD by in vivo confocal microscopy ( IVCM).We retrospectively reviewed 103 eyes of 52
patients with
MGD and 62 eyes of 31 non - MGD
patients . -
pubmed
Worldwide , over 6 million people are infected with
Trypanosoma cruzi , the pathogen that causes
Chagas disease (
CD ) . -
pubmed
We described a 55 - year - old
man , in whom the first manifestation of
retroperitoneal fibrosis (
RPF ) was only coronary arterial involvement , which had no periaortic or peri - iliac and urinary system retroperitoneum involvement in general and other systemic clinical manifestations . -
pubmed
Hepatitis C virus (
HCV ) is common among people living with
human immunodeficiency virus (
PLWH ) . -
pubmed
Extrahepatic manifestations of
HCV , including
myocardial infarction (
MI ) , are a topic of active research . -
pubmed
We examined the association between
HCV and
MI in the Centers for
Acquired Immunodeficiency Syndrome Research Network of Integrated Clinical Systems , a multi - center clinical cohort of PLWH . -
pubmed
We estimated the association between chronic
HCV ( RNA+ ) and time to
MI adjusting for demographic characteristics , cardiovascular risk factors , clinical characteristics and history of injecting drug use . -
pubmed
HCV was associated with a 46 % greater risk of
T2MI ( adjusted hazard ratio ( aHR ) 1.46 , 95 % CI : 1.09 , 1.97 ) but not
T1MI ( aHR 0.87 , 95 % CI : 0.58 , 1.29 ) . -
pubmed
In an exploratory cause - specific analysis of
T2MI ,
HCV was associated with a 2 - fold greater risk of
T2MI attributed to
sepsis ( aHR 2.01 , 95 % CI : 1.25 , 3.24 ) . -
pubmed
We compared the
recurrence - free survival ( RFS ) associated with CF plus
Adriamycin (
ACF ) with that associated with CF plus
docetaxel (
DCF ) to select an alternative regimen in a new phase III trial investigating the optimal neoadjuvant treatment of
patients with
ESCC . -
pubmed
PATIENTS AND METHODS :
Patients with resectable advanced
ESCC were randomly assigned to either
ACF (
Adriamycin 35 mg / m2 ,
cisplatin 70 mg / m2 i.v . -
pubmed
CONCLUSION : Compared with
ACF ,
DCF chemotherapy was associated with prolonged RFS for
patients with resectable advanced
ESCC . -
pubmed
Methods : Since coronary artery bypass surgery ( CABG ) represents a reversible
ischemia - reperfusion sequence , we assessed if statin reload is effective in
patients undergoing off - pump CABG ( n = 100 ) in limiting
myocardial injury . -
pubmed
CONCLUSION : miR-29b potentiates
TMZ sensitivity against
GBM cells by inducing autophagy and the combined use of miR-29 mimic and
TMZ might represent a potential therapeutic strategy for
GBM patients . -
pubmed
Combined Mesenchymal Stromal Cell Therapy and ECMO in
ARDS : A Controlled Experimental Study in
Sheep . -
pubmed
METHODS :
ARDS was induced in 14
sheep , after which they were established on veno - venous ECMO . -
pubmed
In male
Wistar rats ,
systemic inflammation was induced by a tail vein injection of lipopolysaccharides ( LPS challenge ; 12 mg / kg ) . -
pubmed
Patients with
type 2 diabetes exhibit higher cardiovascular risk than normal
individuals . -
pubmed
Optimal blood
glucose levels are rarely achieved in
diabetic patients . -
pubmed
CONCLUSION : Analysis of CMT for
patients with early - stage
HL demonstrates variability in RT dose , including increasing use of 20 Gy and decreasing use of high doses > 36 Gy . -
pubmed
[ Correlation analysis of the prognostic value of serum
hyaluronic acid for
breast cancer patients ] . -
pubmed
Objective : To explore the correlation between preoperative serum
hyaluronic acid ( HA ) level and prognosis of
breast cancer patients . -
pubmed
Methods : The 98
patients with
breast cancer who underwent surgical treatment in the Oncology Department of Sir Run Run Shaw Hospital , Zhejiang University School of Medicine from January 2004 to November 2014 in a historical cohort were included , aged ( 52.5 + -9.4 ) years . -
pubmed
OBJECTIVE : This study aimed to compare the diagnostic performance of cardiac biomarkers and to evaluate the optimal cut - off values for echocardiographic
cardiac injury prediction in
patients with
carbon monoxide ( CO ) poisoning . -
pubmed
METHODS : This retrospective observational cohort study included adult
patients with acute
CO poisoning . -
pubmed
Patients who did not undergo transthoracic echocardiography , which was used to define
patients with
cardiac injury ( ejection fraction < 55 % ) , were excluded . -
pubmed
Fifteen ( 13.2 % )
patients had
cardiac injury . -
pubmed
Aim To identify new predictors for vulnerability of
atherosclerotic coronary plaques in
patients with stable
ischemic heart disease (
sIHD).Material and methods This prospective , single - center study included 58
patients with
sIHD . -
pubmed
On a set of pilot data , accuracy of
bradykinesia prediction is comparable to that recorded by blinded
human experts . -
pubmed
Mapping the Alterations of
Glutamate Using
Glu - Weighted CEST MRI in a
Rat Model of
Fatigue . -
pubmed
The purpose of this study is to map the alternations of brain
glutamate in a
rat model of
fatigue . -
pubmed
Methods :
Rats were subjected to 10 days
fatigue loading procedure (
fatigue group ) or reared without any
fatigue loading ( control group ) . -
pubmed
Spontaneous activities of
rats in the
fatigue group were recorded from 3 days before
fatigue loading to 4 days after the end of
fatigue loading . -
pubmed
Results :
Rats in the
fatigue group exhibited significant reduced spontaneous activities after 10 - day
fatigue loading . -
pubmed
In the entire cohort , the transection line was changed in 2
patients , resulting in no
AL . -
pubmed
Nevertheless ,
AL still developed in 6
patients ( 5.4 % ) , 5 of whom were in the MF group , and delayed
TAP was found in 5 of 6
patients . -
pubmed
External validation of two predictive models for
postoperative fever after retrograde intrarenal surgery ( RIRS ) in pediatric
patients . -
pubmed
OBJECTIVE : The aim of this study is to validate the efficacy and reliability of two predictive models for
postoperative fever after retrograde intrarenal surgery ( RIRS ) in pediatric
patients Materials and Methods : A total of 124
children who were treated with RIRS between August 2014 and August 2020 in our center were included . -
pubmed
Eventually , 21
children ( 16.9 % ) were suffered from
postoperative fever . -
pubmed
21 pediatric
patients ( 16.9 % ) were suffered from
postoperative fever . -
pubmed
Nomogram 1 presented with better predictive power for
postoperative fever after RIRS in pediatric
patients . -
pubmed
A series of
patients with
congenital blood and lymph anomalies of the lower limb investigated and treated at St Thomas 's Hospital , London , are reviewed . -
pubmed
Patients in the arteriovenous shunt group had large hyperplastic lymph pathways , which were possibly either congenital or a
hypertrophic response . -
pubmed
There were 5
deaths in the series , 4 of these being in the scattered
angioma group and in
patients in whom the
deformities extended beyond the limb into the trunk . -
pubmed
In 13
patients with
hypertension and
renal artery stenosis the
stenosis was dilated by an intra - arterial balloon catheter under local anaesthesia . -
pubmed
Dilatation of
renal artery stenosis by an intra - arterial balloon catheter is a promising treatment for
patients with
hypertension and
renal artery stenosis . -
pubmed
Circulatory effects of
magnesium sulfate in normotensive and renal
hypertensive pregnant
sheep . -
pubmed
We have studied the effects of
magnesium sulfate (
MgSO4 ) administration in chronically instrumented normotensive and
hypertensive pregnant
sheep . -
pubmed
Animals of 90 to 144 days ' gestation were divided in two groups ; those with normotensive arterial pressure and those in which
renovascular hypertension had been produced . -
pubmed
Because
MgSO4 produced no significant hemodynamic changes , we feel that : ( 1 ) its use in obstetrics must be based on its anticonvulsant action and ( 2 )
MgSO4 in either normotensive or
hypertensive patients is not associated with
impairment of uteroplacental blood flow . -
pubmed
During one six - month period 11
patients were referred with a diagnosis of
coronary artery disease , because of recurrent episodes of severe , prolonged retrosternal
chest pain necessitating from one to seven hospital admissions per patient for " suspect
myocardial infarction " . -
pubmed
Selective coronary arteriograms were normal in 10
patients and revealed nonobstructive
coronary artery disease in the 11th
patient . -
pubmed
Hypertrophy of
rat extensor digitorum longus muscle injected with
bupivacaine . -
pubmed
Enterotoxin producing
strains of
E. - pubmed
Rarely
giardia lamblia ,
entamoeba histolytica and
cryptosporidia are causative organisms . -
pubmed
for 5 days we were able to demonstrate a significant clinical and bacteriologic effect in 132
patients with
salmonellosis and
campylobacteriosis . -
pubmed
Patients who were treated with the drug included 2 with complicated
urinary tract infections (
UTI ) , 29 with
chronic prostatitis and 3 with chronic non - chlamydial
epididymitis . -
pubmed
In 2 cases of chronic
UTI , infected by
P. - pubmed
For evaluating the effectiveness on
chronic prostatitis , the
patients were divided into 2 groups ; group I ( G - I ) was chronic bacterial ( number of isolates including GNR or
E. - pubmed
Two
murine models of
polycystic kidney disease (
PKD ) in
humans are currently available : the infant - type cpk in
mice and the adult - type pcy mutation in
mice . -
pubmed
Our linkage analysis was to determine whether these genes are allelic forms of the same gene , or infant - type and adult - type
PKD resulting from homozygous and heterozygous mutation , as in the
rat Cy gene . -
pubmed
Over - expression of an endogenous milk protein gene in transgenic
mice is associated with
impaired mammary alveolar development and a milchlos phenotype . -
pubmed
Cardioversion was achieved in 70 % of
patients with
atrial fibrillation and in 96 % of
patients with
atrial flutter . -
pubmed
[ The effect of exercise on blood gases and
oxygen transport in
patients with
chronic obstructive pulmonary disease ] . -
pubmed
The effect of exercise on pulmonary gas exchange and
oxygen transport was studied in 42
patients with
COPD . -
pubmed
Our data imply that PO2 changes of
COPD patients during exercise may be related to the
patient 's ventilation , pulmonary gas exchange and mixed venous PO2 levels . -
pubmed
Sixty - four traumatically
brain injured patients were divided into three groups . -
pubmed
A 43 - year - old
man had severe upper
abdominal pain and
weight loss of 8 kg for over three months . -
pubmed
Long - term effect of
ipratropium bromide and
fenoterol on the
bronchial hyperresponsiveness to
histamine in
children with
asthma . -
pubmed
We studied the effects of the anticholinergic
ipratropium bromide ( 40 micrograms three times daily ) and the beta - agonist ,
fenoterol ( 0.2 mg three times daily ) , both administered by powder inhaler , on
bronchial hyperresponsiveness ( BHR ) to
histamine in
children , aged 7 to 15 years with mild stable
asthma and limited
bronchoconstriction who had a highly increased BHR . -
pubmed
We concluded that long - term treatment with
ipratropium bromide or
fenoterol had no effect on BHR in
children with mild stable
asthma . -
pubmed
Subclass specificity of antibodies were studied in sera of 108
patients suffering from
pollinosis . -
pubmed
Antibodies of this isotype were found in the majority of
patients with
tree pollen allergy but not in
patients with
grass pollen allergy . -
pubmed
In case of
hepatitis further investigations were performed for heterophilic
infectious mononucleosis antibodies and for
hepatitis B virus DNA . -
pubmed
Somatostatin inhibits the ventilatory response to
hypoxia in
humans . -
pubmed
Ten
strains of adenovirus representing 10 serotypes were administered intratracheally to 3 - week - old specific - pathogen - free
chickens , which also received 2.5 X 10(5 ) colony - forming units of a pathogenic
Escherichia coli intranasally . -
pubmed
A prospective randomized trial was performed in 44
patients undergoing elective coronary artery bypass grafting to assess the effects of the membrane oxygenator and
dipyridamole on platelet counts , platelet activation products , and
postoperative bleeding . -
pubmed
Patients who were randomized to receive a bubble oxygenator and no
dipyridamole had the lowest postoperative platelet counts , the greatest
blood loss , and the most blood products transfused . -
pubmed
Platelet counts were highest and
blood loss was least in
patients randomized to receive a membrane oxygenator and
dipyridamole ( p less than .05 ) . -
pubmed
[ Initial clinical experience using an interdisciplinary management concept for pregnant
patients with
liver damage ] . -
pubmed
Twenty
patients with metastatic
colon cancer without prior chemotherapy received 2 g / m2 of
5 - fluorouracil ( 5 - FU ) infused over 24 h for 5 days preceded by
allopurinol 900 mg orally for 1 week and then continued during , and for 1 week after the infusion was completed . -
pubmed
Fourteen
patients were evaluable for both response and
toxicity . -
pubmed
No significant hematologic
toxicity was seen but 18 of 19
patients evaluable for
toxicity developed
mucositis resulting in dose reductions in 3
patients and refusal of a second course by 2 additional
patients . -
pubmed
The epidemiology of
diabetes in
mammals ( with comments in detail on the Tongaat Sugar Survey Company ) . -
pubmed
[ Hepatography in assessing liver function in
patients with
circulatory insufficiency ] . -
pubmed
Studies of
mammary carcinoma metastasis in a
mouse model system . -
pubmed
The biological and metastatic properties of cells from a
murine mammary adenocarcinoma ,
MT1 , were studied during serial transplantation in syngeneic hosts . -
pubmed
Immune complexes in
human malignant tumours . -
pubmed
High levels of immune complexes have been detected in the serum of
patients with
malignant solid tumours ,
leukemias and
lymphomas . -
pubmed
Prophylactic antibiotics were given to a group of 389 orthognathic surgery
patients , with the development of 1 case of acute and 12 cases of
chronic infection . -
pubmed
One case of chronic
infection appeared in another group of 76
patients who had not received prophylactic antibiotics . -
pubmed
The authors present the radiotherapeutic results achieved in 56
patients with
endocrine ophthalmopathy , 15 out of them with severe , so - called malignant course . -
pubmed
The respiratory muscles and neurons activity in the transitional process from rhythmic respiration to its cessation and reappearance of the usual rhythmic breathing after the
apnea was registered in the acute experiments on the anesthetized
cats and
rabbits under the action of extra intrapulmonary
oxygen pressure or intravenous injection of
sodium cyanide . -
pubmed
Differential effect of
nerve injury at birth on the activity pattern of reinnervated slow and fast muscles of the
rat . -
pubmed
Total
blindness developed in an adult
Melanesian man 36 hours after he drank 100 mL of 100 %
methanol . -
pubmed
In the large - scale Evaluation of c7E3 for the Prevention of Ischemic Complications ( EPIC ) trial that involved high - risk
patients undergoing coronary intervention procedures , a monoclonal antibody Fab fragment ( c7E3 ) directed against this receptor , administered as a bolus and and through infusion , significantly reduced the 30 - day incidence of major
ischemic events relative to placebo . -
pubmed
Of 38
patients who underwent surgery since 1984 , 34 had low
rectal cancer and four
carcinoid or large villous
adenoma . -
pubmed
Four
patients developed local
recurrence during a median observation period of 3 years . -
pubmed
Cytotoxic effects are demonstrated against
human leukemia and
melanoma cell lines proliferating in tissue culture and against xenografts of
human breast cancer and
sarcoma growing in
nude mice . -
pubmed
Pharmacological interference with
tissue hypercatabolism in
tumour - bearing
rats . -
pubmed
We also discuss the probable aetiology of the
strokes and whether cardiac echocardiography should be performed in these
patients . -
pubmed
METHODS : Spleen cells from
mice immunized with prostatic epithelial cells prepared from
benign prostatic hyperplasia tissue were fused with
myeloma cells
X63Ag8 - 653 . -
pubmed
To examine the influence of chronic
hyperglycemia ,
rats were subjected to 90 % partial pancreatectomy ( Px ) , which produced
glucose levels of 10.9 - 20.8 mM. -
pubmed
Twenty - two
patients with
hyperthyroidism were included in a prospective , randomized and placebo controlled study . -
pubmed
Diltiazem can be used in
patients with
hyperthyroidism to alleviate adrenergic manifestations . -
pubmed
A solitary
Peutz - Jeghers - type polyp of the rectum in a 64 - year - old Japanese
man is reported . -
pubmed
Weanling
rats exposed to maternal low - protein diets during discrete periods of gestation exhibit differing severity of
hypertension . -
pubmed
In the
rat ,
hypertension is induced by fetal exposure to maternal low - protein diets . -
pubmed
Hypertension was observed in
rats exposed to low protein during the following gestational periods : days 0 - 7 , days 8 - 14 and days 15 - 22 . -
pubmed
Fetal exposure to maternal low - protein diets for any period in gestation may programme
hypertension in the
rat . -
pubmed
Following in vitro lipofection transfection of the
rat glioma cell line
A15A5 with the plasmid transgene
CMV / HyTK , which confirms
hygromycin resistance and
ganciclovir sensitivity , a series of experiments was planned in which the " bystander " phenomenon would be evaluated using the
rodent implantation
glioma model . -
pubmed
However examination of the brain of
rodents in which the
A15A5HyTK cells were implanted showed no evidence of
glioma growth . -
pubmed
Furthermore ,
rodents having intracerebral implantation of ( i ) wild
A15A5 and
A15A5HyTK cells in a 50/50 mix , ( ii ) wild
A15A5 and
A15A5HyTK cells in a 90/10 mixture and ( iii ) wild
C6 and
A15A5HyTK cells in a 50/50 mix all failed to grow macroscopic
tumours by 15 - 17 days irrespective of whether the animals had been administered
ganciclovir (
GCV ) in the week before sacrifice . -
pubmed
The implications of this study for gene therapy of
human malignant glioma are discussed . -
pubmed
In spite of this superiority , the long - term outcome for most
patients with relapsed or refractory
NHL remains unfavorable . -
pubmed
Cholesterol - lowering therapy in women and elderly
patients with
myocardial infarction or
angina pectoris : findings from the Scandinavian
Simvastatin Survival Study ( 4S ) BACKGROUND : The Scandinavian
Simvastatin Survival Study ( 4S ) demonstrated pronounced reductions in mortality and major coronary events in a cohort of
patients with established
coronary heart disease (
CHD ) . -
pubmed
METHODS AND RESULTS : The 4S cohort of 4444
CHD patients included 827
women and 1021
patients & gt ; or = 65 years of age . -
pubmed
In
patients & gt ; or = 65 years of age in the
simvastatin group , relative risks ( 95 % confidence intervals ) for clinical events were as follows : all - cause mortality , 0.66 ( 0.48 to 0.90 ) ;
CHD mortality , 0.57 ( 0.39 to 0.83 ) ; major coronary events , 0.66 ( 0.52 to 0.84 ) ; any
atherosclerosis - related event , 0.67 ( 0.56 to 0.81 ) ; and revascularization procedures , 0.59 ( 0.41 to 0.84 ) . -
pubmed
In cultured
rat alveolar epithelial cells ( RAEC ) Exo A caused
cytotoxicity as measured by
51Cr release from these cells . -
pubmed
Four
patients ages 40 - 65 y ( mean : 53.75 + /- 10.59 ) , three with
mesenteric thrombosis , and one with
Crohn ' s disease were studied . -
pubmed
The effects of
tacrolimus ointment on immediate , late and delayed - type cutaneous
allergic reactions and normal skin thickness were investigated in
mice and compared with those of
steroid ointments . -
pubmed
After
retrovirus - mediated gene transfer of a suppressor gene an increase of
tumor cell apoptosis was observed . -
pubmed
We have previously shown that polymorphonuclear leucocytes ( PMN ) harvested from
children with
cancer and exposed to chemotherapy exhibit defective bactericidal activities against both Gram - positive and Gram - negative microorganisms as well as accelerated apoptosis . -
pubmed
PATIENTS : All CAPD
patients who developed
bacterial or culture - negative
peritonitis beyond 28 days of a previous episode and without evidence of
septicemia , associated
tunnel infection , or known sensitivity to trial medications were accepted into the clinical trial . -
pubmed
Risk assessment of
bovine spongiform encephalopathy transmission through bone graft material derived from
bovine bone used for dental applications . -
pubmed
The recent incidents of
bovine spongiform encephalopathies (
BSE ) in
humans have underscored this likelihood . -
pubmed
RESULTS : Results from the analyses conducted using both models showed that the risk of disease (
BSE ) transmission from BGS was negligible and could be attributed to the stringent protocols followed in sourcing and processing of the raw
bovine bone used in the commercial product . -
pubmed
The purpose of this study was to determine the effect of treatment with
donepezil 5 mg qd on cognitive evoked potentials ( EPs ) of
patients with
AD . -
pubmed
Patients who have had their jaws irradiated as part of management of
head and neck malignancy are at risk of
osteoradionecrosis (
ORN ) following tooth extraction . -
pubmed
Seven
patients who did not have HBO and one who did ( 15 per cent ) developed
ORN . -
pubmed
Ara - C , another antineoplastic agent commonly used in
haematologic malignancies , induced both apoptosis and
iron depletion in
human acute myeloid leukaemic cells . -
pubmed
Following
toxicity , the
dogs received either
digoxin ( 0.018 mg / kg ) ( DIG ) ( n = 8) or saline ( No - DIG ) ( n = 8) . -
pubmed
Animal weight , does of
VER administered during the
toxicity phase , and baseline values were included as covariates . -
pubmed
To investigate whether the degree of
splenomegaly correlates with the degree of immune stimulation , whether prophylaxis or recent treatment play a role , and whether short therapy alone is effective , we examined retrospectively the medical records of expatriates with exposure to
P. - pubmed
A virus closely related to
cherry green ring mottle virus (
CGRMV ) was isolated from a tree displaying typical symptoms of
cherry necrotic rusty mottle disease . -
pubmed
Adjuvant chemotherapy after resection of
hepatocellular carcinoma causes deterioration of long - term prognosis in cirrhotic
patients : metaanalysis of three randomized controlled trials . -
pubmed
BACKGROUND : The goal of the current study was use metaanalysis to evaluate the effect of postoperative adjuvant chemotherapy after resection of
hepatocellular carcinoma (
HCC ) , especially in cirrhotic
patients . -
pubmed
METHODS : One hundred - eight
patients with radical resection of
HCC were included in 1 of 3 prospective randomized control studies that used different postoperative chemotherapy protocols . -
pubmed
Postoperative chemotherapy using the current protocols failed to improve
patient outcome in all
patients and failed to improve
disease - free and overall survival in any
patients who were included in individual protocols . -
pubmed
In
patients with
cirrhosis , postoperative chemotherapy was associated with significantly worse
disease - free ( P = 0.0376 ) and overall survival rates ( P = 0.0077 ) . -
pubmed
CONCLUSIONS : The current study indicated that
cancer recurrence in the remnant liver is enhanced and the long - term outcome is deteriorated by postoperative chemotherapy after resection of
HCC in cirrhotic
patients . -
pubmed
The proposed method of surgical treatment of
patients with
scar deformations and
defects of soft tissues of the anterior abdominal wall and lumbosacral zone was used in 30
patients . -
pubmed
Acute
dermotension permits to remove large
scar defects and restore natural integument in
patients with
burn trauma . -
pubmed
Unilateral hot plate test : a simple and sensitive method for detecting central and peripheral
hyperalgesia in
mice . -
pubmed
The sensitivity and usefulness of the UHP test for performing
pain studies in
mice is described . -
pubmed
Thermoregulatory responses of two
mouse Mus musculus strains selectively bred for high and low
food intake . -
pubmed
We examined the thermoregulatory responses of male and female
mice Mus musculus that had been divergently selected on voluntary food intake , corrected for body mass , to produce a high - intake and a low - intake
strain . -
pubmed
Lower critical temperature in both
strains appeared to be around 28 degrees C. At 30 degrees C there was a significant
strain effect on resting metabolic rate , with high
strain mice having greater metabolism than low
strain mice . -
pubmed
Thermal conductance was significantly related to strain and sex ,
mice from the high
strain and males having greater thermal conductances than
mice from the low
strain and females . -
pubmed
All
patients showed a
hypertropia of the fellow eye . -
pubmed
All
patients were symptomatic prior to
strabismus surgery : 4 of 15
patients with " tilt " ( objects appearing subjectively rotated with respect to their true orientation ) ; 2 of 15
patients with
diplopia ; and 9 of 15
patients with both . -
pubmed
Postoperatively , 7
patients had residual milder symptoms :
tilt , 2
patients ;
diplopia , 3
patients ; and both , 2
patients . -
pubmed
No
patient showed binocular function ( stereopsis or motor fusion ) after macular translocation , either before or following
strabismus surgery for
cyclotorsion . -
pubmed
We present a
PNET arising from the kidney in a 23 - year - old female
patient . -
pubmed
The hypophysis was exposed to radiation in 11
patients with
prostatic cancer . -
pubmed
RESULTS : A 54 - year - old
woman underwent conductive keratoplasty for
hyperopia . -
pubmed
It is important to select
patients with limited
SCLC who are able to tolerate concurrent chemotherapy and accelerated TRT . -
pubmed
However , the type
strains of
A. - pubmed
Electrophysiological approach to the study of
essential tremor in
children and adolescents . -
pubmed
There are many reports on neurophysiological features in adult - onset
essential tremor , but to our knowledge there have been no similar investigations of
essential tremor in
children . -
pubmed
We conducted a neurophysiological study of nine
children , six males and three females , with definite essential
tremor . -
pubmed
Effect of species from the section Monoverticillata , genus Penicillium , on the growth of
cabbage seeds and on certain
bacterial plant diseases ] . -
pubmed
[ Dynamics of immunological indices in
patients with
neural rheumatism in various modes of therapy ] . -
pubmed
Occupational contact dermatitis , with
asthma and
rhinitis , from
camomile in a cosmetician also with contact
urticaria from both
camomile and
lime flowers . -
pubmed
[
Renal failure in an
HIV patient ] . -
pubmed
' Candidatus
Phytoplasma cynodontis ' , the phytoplasma associated with
Bermuda grass white leaf disease . -
pubmed
Bermuda grass white leaf ( BGWL ) is a destructive ,
phytoplasmal disease of
Bermuda grass (
Cynodon dactylon ) . -
pubmed
Hypertension and
urinary tract infection each were found in 50 % of the
patients while 6 ( 30 % ) presented with features of
renal failure . -
pubmed
Aberrant intracellular
calcium signaling in olfactory neurons from
patients with
bipolar disorder . -
pubmed
OBJECTIVE : The authors examined the feasibility of using olfactory receptor neurons from living
patients to test whether
calcium signaling is altered in a neuronal cell population in
bipolar disorder . -
pubmed
METHOD : Ratiometric fluorescence photomicroscopy was used to assess basal and stimulus - induced changes in intracellular
calcium levels in biopsy - derived olfactory receptor neurons from seven euthymic
patients with
bipolar disorder who were medication - free , 10 euthymic
patients with
bipolar disorder who were treated with mood stabilizers , and 17 age- and sex - matched comparison
subjects without
bipolar disorder . -
pubmed
Although the genetic control of
melanism has been studied in
chickens and other domestic species , little was known about the molecular genetics of melanin distribution in wild birds until recently . -
pubmed
Percutaneous cardiopulmonary support ( PCPS ) is a powerful resuscitation tool for
patients in
cardiogenic shock . -
pubmed
We describe the case of a 75 - year - old
woman who required extended PCPS for
cardiogenic shock secondary to
coronary spasm after on - pump beating coronary artery bypass grafting . -
pubmed
This technique appears to be useful in treating
limb ischemia and may have application in
patients with
arterial occlusive disease who are dependent on mechanical support . -
pubmed
Focal
ischemia , which was studied as an experimental
stroke model , was induced in 3- and 24 - month - old
rats by unilateral common
carotid artery occlusion associated with 24 h of
hypoxia . -
pubmed
In each
patient , the coronary risk factors (
CRF ) , such as
hypertension , high
cholesterol ,
diabetes mellitus ,
obesity , positive family history , and smoking were evaluated . -
pubmed
New trial awarded over
man 's HIV - related
fatigue . -
pubmed
2 -( 8 - hydroxy-6 - methoxy-1 - oxo-1h-2 - benzopyran-3 - yl ) propionic acid , an inhibitor of angiogenesis , ameliorates renal alterations in
obese type 2 diabetic mice . -
pubmed
In the present study , we examined the therapeutic efficacy of
2 -( 8 - hydroxy-6 - methoxy-1 - oxo-1H-2 - benzopyran-3 - yl ) propionic acid (
NM-3 ) , a small molecule
isocoumarin with antiangiogenic activity , using diabetic
db / db mice , a model of
obese type 2 diabetes . -
pubmed
PATIENTS : Nineteen heterogeneous
emphysema patients . -
pubmed
Baseline BODE index (
BMI , degree of airflow obstruction and
dyspnea , exercise capacity as measured by the 6 - min walk test [ 6MWT ] ) was 7 to 10 in 10
patients ( estimated 4 - year mortality , 80 % ) and 5 to 6 in 9
patients ( estimated 4 - year mortality , 40 % ) . -
pubmed
Nonsustained
atelectasis was observed within 48 h in 2 of 12
patients with
right upper lobe occlusion . -
pubmed
PARTICIPANTS : Eighteen
patients met inclusion criteria , 10
trauma and 8 surgical . -
pubmed
All but 1
patient ( 17/18 ) had resolution of
coagulopathic bleeding with rFVIIa , and all clinical responders ( n = 17 ) ( defined as clinical cessation of
bleeding within 24 hours determined by either attending surgeon or chief resident progress note ) had a decrease in PT to normal range . -
pubmed
Sleep disturbances reported by refractory partial - onset
epilepsy patients receiving polytherapy . -
pubmed
PURPOSE : Although
sleep disturbances are common in
epilepsy , few studies examined the prevalence and impact of
sleep disturbance in
epilepsy patients . -
pubmed
METHODS : We surveyed 201 adult partial - onset
epilepsy patients taking stable regimens of two or more antiepileptic medications . -
pubmed
To determine whether this defect leads to alterations in the internal three - dimensional organization of mitochondrial membranes , we applied electron microscopic tomography to lymphoblast mitochondria from
BTHS patients and controls . -
pubmed
METHODS :
Patients , who underwent uneventful phacoemulsification with intraocular implantation and were referred for Nd : YAG laser capsulotomy owing to PCO , were prospectively examined for the presence of
CBS . -
pubmed
RESULTS : Of 655
patients referred for capsulotomy , eight had an associated
CBS in that eye . -
pubmed
The aims of this paper were to determine the serological response to
HSV-1 and
HSV-2 infection among pregnant women and women of reproductive age and seroprevalence of
HSV-1 and
HSV-2 antibodies among pregnant women and women of reproductive age . -
pubmed
Complex regional pain syndrome in a
patient with
spinal cord injury : management with pulsed radiofrequency lumbar sympatholysis . -
pubmed
OBJECTIVES : To report a case with bilateral
lower extremity complex regional pain syndrome (
CRPS ) in a
patient with
paraplegia occurring following
spinal disc herniation surgery , who was treated successfully with
pulse radiofrequency ( PRF ) lumbar sympatholysis . -
pubmed
RESULTS : The
patient underwent a diagnostic sympathetic
ganglion blockade with
bupivacaine , which resulted in a marked decrease in the
pain and
edema of the feet . -
pubmed
CONCLUSION : When treatment of
CRPS fails with conventional modalities , PRF sympatholysis may be used for control of
pain and other symptoms in such
patients . -
pubmed
The level of defense against
great spotted cuckoo (
Clamator glandarius ) parasitism in different European populations of magpie (
Pica pica ) depends on selection pressures due to parasitism and gene flow between populations , which suggests the existence of coevolutionary hot
spots within a European metapopulation . -
pubmed
Percussion and postural drainage have been widely employed for mechanically ventilated
patients but have not been shown to reduce ventilator - associated
pneumonia or
atelectasis . -
pubmed
Intrapulmonary percussive ventilation combines percussion with hyperinflation and a simulated
cough , but the evidence for intrapulmonary percussive ventilation in mechanically ventilated
patients is insufficient to support routine use . -
pubmed
PURPOSE :
Patients with
von Hippel - Lindau disease may require repeat partial nephrectomies to avoid the need for renal replacement therapy . -
pubmed
In the last 2 decades , a variety of different molecular typing methods have been developed to differentiate
strains of
Mycobacterium avium subsp . - pubmed
To further understand this response , we tested enterostatin 's effect in a
human hepatoma cell line (
HepG2 cells ) that was subjected to
glucose deprivation , a condition known to induce angiogenesis in other
tumor cell lines . -
pubmed
RESULTS : Among 3,434
patients 266 ( 7.7 % ) developed an incident
ischemic cerebrovascular event . -
pubmed
Cataract ( 12.47 per 100 ) was the major ocular comorbidity ;
high blood pressure ( 21.14 per 100 ) and
diabetes mellitus ( 15.99 per 100 ) were the main systemic comorbidities among 415
patients with
retinal diseases . -
pubmed
The prevalence of
low vision on the basis of best - corrected and presenting visual acuity was 0.63 and 2.87 per 100 in 415
patients with
retinal disease . -
pubmed
Mouse models of
Rett syndrome : from behavioural phenotyping to preclinical evaluation of new therapeutic approaches . -
pubmed
The discovery of a monogenic origin for
RTT and the subsequent generation of
RTT mouse models provided a major breakthrough for
RTT research . -
pubmed
Although the characterization of these mutant
mice is far from complete , they recapitulate several
RTT symptoms . -
pubmed
This review provides an overview of the behavioural domains so far investigated in these models , including the very few
mouse data concerning the developmental course of
RTT . -
pubmed
BACKGROUND :
Patients with
enterocutaneous fistulas undergo long intensive treatment . -
pubmed
METHODS : Consecutive
patients treated for enterocutaneous
fistula between 1990 and 2005 were eligible for this retrospective study . -
pubmed
An aqueous slurry of gamma - irradiated sterilized dried figs was inoculated with toxigenic
strains of
Aspergillus flavus and
Aspergillus parasiticus . -
pubmed
[ A case with
hand , foot and mouth disease associated with central nervous symptoms related to
enterovirus 71 in Beijing ] . -
pubmed
Longitudinal prognostic value of serum " free "
copper in
patients with
Alzheimer disease . -
pubmed
Hyperlipidemic patients with higher levels of free
copper seemed more prone to worse
cognitive impairment . -
pubmed
These include ( 1 ) updating the definition of
SE to make it more clinically relevant , ( 2 ) consideration of faster ways to initiate first - line
benzodiazepine therapy in the prehospital environment , ( 3 ) moving to second - line agents more quickly in refractory status in the emergency department , and ( 4 ) increasing detection and treatment of unrecognized nonconvulsive
SE in comatose neurologic emergency
patients . -
pubmed
METHODS : Initially antiproliferating effect of the antisense oligomers was studied in vitro by measuring the rate of
tritiated thymidine incorporation into DNA in
rat hepatocellular carcinoma cells in culture medium . -
pubmed
Based on the findings , the antisense treatment was carried out in
rat hepatocarcinogenesis model - initiated with
diethylnitrosamine and promoted using
2 - acetylaminoflourene . -
pubmed
Primary osteoplasty using calvarian bone in
patients with
cleft lip , alveolus and palate . -
pubmed
METHODS : After primary osteoplasty with calvarian bone at an average age of 24 months ( 4 - 56 months ) radiographic assessment was carried out in 31
patients with 40
alveolar clefts . -
pubmed
METHODS : A matrix - associated transepithelial resistance invasion ( MATRIN ) assay was used to assess SFs from
patients with
RA in comparison with SFs from
patients with
osteoarthritis (
OA ) . -
pubmed
METHODS A total of 300 refractory
FD patients and 450 healthy blood donors ( BD ) were studied . -
pubmed
Assessment of progenitor cell responses to pathogenic intestinal bacteria could provide a measure of predisposition for apoptotic enterocyte - assisted
intestinal dysplasias in
humans . -
pubmed
In both
strains , subAB was physically associated with tia , an invasion genetic determinant of enterotoxigenic
E. - pubmed
Role of video - assisted thoracoscopy in
patients with
ovarian cancer and
pleural effusion . -
pubmed
METHODS : We retrospectively evaluated 16 VAT procedures in 15
patients with advanced
ovarian malignancies and
pleural effusions . -
pubmed
RESULTS : Common causes for admitting
children to intensive care units are
head injuries ;
septic shock and
respiratory failure . -
pubmed
Non - invasive pressure ventilation is used increasingly in
children with
respiratory failure . -
pubmed
Development of tolerance ,
withdrawal symptoms and physical dependency are substantial clinical problems in long - term sedation and analgesic treatment of
children , and are associated with high doses and long duration of infusions . -
pubmed
The
patient was initially treated for ST - segment elevation
myocardial infarction and symptoms resolved . -
pubmed
DISCUSSION :
Takotsubo cardiomyopathy is commonly triggered by severe emotional or psychological stress and occurs primarily in postmenopausal
women . -
pubmed
CONCLUSIONS :
Takotsubo cardiomyopathy causes a reversible
left ventricle dysfunction which occurs most commonly in postmenopausal
women with or without
cardiovascular disease . -
pubmed
It is likely that these findings , as well as the paucity of
tobacco dependence studies , reflect the relatively small number of psychiatric nurses conducting research as well as the inattention , until recently , of mental health leaders , policy makers , and funders to the importance of
tobacco dependence research in this clinical population . -
pubmed
As
tobacco dependence treatment for those with
mental illnesses and/or
addictive disorders becomes more of a public health priority , opportunities abound for nurse researchers to contribute to the growing evidence in this often neglected area . -
pubmed
The expression of the above genes was measured in the circulating
cancer cells of
pancreatic cancer patients . -
pubmed
We compared their expression rate in
pancreatic cancer patients at different stages to screen for the indicator with highest sensitivity and specificity for the detection of circulating
pancreatic cancer cells . -
pubmed
Energy expenditure during sleep ,
sleep deprivation and sleep following
sleep deprivation in adult
humans . -
pubmed
These findings provide support for the hypothesis that sleep conserves energy and that
sleep deprivation increases total daily EE in
humans . -
pubmed
METHODS : Between June 2004 and June 2005 we observed 471
patients with
PPV . -
pubmed
Out of these , five transformed into the geotropic form during the first examination ; in 5
patients we observed
geotropic nystagmus at the follow - up visit ; the last 20 never showed
geotropic nystagmus before resolution . -
pubmed
Recent randomized controlled trials , however , have failed to demonstrate the efficacy of therapeutic
hypothermia (
TH ) in
patients with
TBI . -
pubmed
We quantified changes in chronically retracted tendons undergoing no repair or a staged repair involving an initial re - lengthening of the musculotendinous unit by traction in a
sheep model of massive
rotator cuff tear . -
pubmed
Wound catheters provided no significant analgesia at rest or on activity , except in
patients undergoing gynecological and obstetric surgery at 48 h ( P=0.03 ) . -
pubmed
No significant differences in side effects were found , except for a lower risk of
wound breakdown ( P=0.048 ) and a shorter length of hospital stay ( P=0.04 ) in
patients receiving LA . -
pubmed
LA injected via
wound catheters did not reduce
pain intensity , except at 48 h in a subgroup of
patients undergoing obstetric and gynecological surgery . -
pubmed
The purpose of this study was to retrospectively evaluate the complications of 58
patients who underwent surgery for
mandibular condylar process fractures . -
pubmed
There were 22
patients with
bilateral condyle fractures and 36
patients with
unilateral condyle fractures , accounting for 65 surgeries . -
pubmed
Treatment outcomes for different subgroups of
nasopharyngeal carcinoma patients treated with intensity - modulated radiation therapy . -
pubmed
Herein , we evaluated the outcomes of
NPC patients treated with IMRT and further explored treatment strategy to improve such outcome . -
pubmed
Our results suggest that the decision of treatment strategy for
NPC patients should consider combinations of T and N stages , and that IMRT alone for early stage
NPC patients can produce satisfactory results . -
pubmed
OBJECTIVE : The long - term event monitoring ( LEM ) study evaluated the lipid - lowering efficacy and safety of
fluvastatin in Japanese
patients with
hypercholesterolemia . -
pubmed
Presence of
diabetes mellitus (
DM ) in
patients without complication significantly increased the incidence in both cardiac events ( 2.37 ) and cerebral events ( 2.15 ) as compared with non - DM
patients for primary prevention ( P & lt ; 0.001 and P & lt ; 0.01 , respectively ) . -
pubmed
For the secondary prevention ,
DM patients with complication of
cardiac disease showed a significantly higher incidence in both cardiac events ( 1.59 ) and cerebral events ( 3.79 ) compared with non -
DM patients ( P & lt ; 0.05 and P & lt ; 0.01 , respectively ) . -
pubmed
In contrast ,
DM patients with complications of
cerebrovascular disease showed a significantly higher incidence in cerebral events ( 2.58 , P & lt ; 0.05 ) , but not cardiac events compared with non - DM
patients . -
pubmed
For secondary prevention ,
hypertension in
patients with complication of
cardiac or cerebrovascular disease did not affect incidence in both cardiac and cerebral events . -
pubmed
Alterations of high -
mannose type N - glycosylation in
human and
mouse osteoarthritis cartilage . -
pubmed
METHODS : Alterations in N - glycans were analyzed in
human OA cartilage and degraded
mouse cartilage by high - performance liquid chromatography and mass spectrometry . -
pubmed
RESULTS : Alterations in high -
mannose type N - glycans were observed in both
human OA cartilage and degraded
mouse cartilage . -
pubmed
The parasite
Leishmania donovani is reported to be the causative agent for
CL in Sri Lanka . -
pubmed
Eight
patients with postoperative recurrent
uterine cancer received HDR - ISBT with or without external beam radiotherapy using our unique ambulatory technique . -
pubmed
melitensis and
Brucella abortus infections in
mice . -
pubmed
Low - dose
theophylline restores
corticosteroid responsiveness in
rats with smoke - induced
airway inflammation . -
pubmed
Patients with
chronic obstructive pulmonary disease (
COPD ) respond poorly to
corticosteroids . -
pubmed
Imaging mass spectrometry to visualize biomolecule distributions in
mouse brain tissue following hemispheric cortical spreading
depression . -
pubmed
Transient elastography to rule out
esophageal varices and
portal hypertensive gastropathy in
HIV - infected individuals with
liver cirrhosis . -
pubmed
BACKGROUND / AIMS : It is recommended that patients with
cirrhosis undergo endoscopic screening to rule out the presence of
gastroesophageal varices : a noninvasive predictive method to identify
cirrhotic patients with a very low risk of
esophageal varices could potentially avoid unnecessary endoscopies . -
pubmed
METHODS : We studied in 85
HIV - infected
patients with
cirrhosis the association between the absence of
esophageal varices and
portal hypertensive gastropathy , assessed by endoscopy , and liver stiffness measurement by transient elastography . -
pubmed
CONCLUSION : Transient elastography combined with platelet count is useful for predicting the absence of
esophageal varices and
portal hypertensive gastropathy and , therefore , avoid unnecessary diagnostic endoscopies in
HIV - infected
patients with
liver cirrhosis . -
pubmed
Denosumab ( Dmab ) and
zoledronic acid (
ZOL ) are antiresorptive agents , with different mechanisms of action , that are indicated for delaying the onset of skeletal - related events in
patients with
bone metastases from
solid tumors . -
pubmed
Dmab ( 0.31 to 160 muM ) had no effect on the viability of
human MDA - MB-436 and
CG5 breast cancer cells or human umbilical vein endothelial cells (
HUVECs ) and no effect on tubule formation or invasion of HUVECs . -
pubmed
Usefulness of whole - body
fluorine-18 - fluorodeoxyglucose positron emission tomography in
patients with
neurofibromatosis type 1 : a systematic review . -
pubmed
To systematically review the role of positron emission tomography ( PET ) with
fluorine-18 - fluorodeoxyglucose (
FDG ) in
patients with
neurofibromatosis type 1 (
NF1 ) . -
pubmed
Only those studies or subsets in studies including whole - body
FDG - PET or PET / CT scans performed in
patients with
NF1 were included . -
pubmed
We identified 12 studies including 352
NF1 patients . -
pubmed
Moreover ,
FDG - PET seems to be an important imaging modality for predicting the progression to
MPNST and the outcome in
patients with
MPNST . -
pubmed
Two studies evaluated the role of
FDG - PET in pediatric
patients with
NF1 . -
pubmed
The
horse had
tachypnea with increased respiratory effort and was in thin body condition . -
pubmed
EMPF is a recently described disease in adult
horses with clinical signs of
fever ,
weight loss and respiratory problems . -
pubmed
The pathological findings include loss of functional pulmonary parenchyma due to extensive nodular interstitial
fibrosis which has been related to
infection with the equine herpesvirus type 5 (
EHV-5 ) . -
pubmed
Preliminary studies on the hypoglycemic effect of
Peganum harmala L. Seeds
ethanol extract on normal and
streptozotocin induced
diabetic rats . -
pubmed
Peganum harmala L. (
Zygophyllaceae ) is a traditional medicine used for the treatment of variety of
human ailments , including antidepression ,
hallucination ,
antileishmaniasis etc . -
pubmed
We report for first time the hypoglycemic activity of the ethanolic extract of this plant at two dose levels of 150 and 250mg / kg bw in
sucrose challenged normal as well as in
rats with
streptozotocin induced
diabetes . -
pubmed
The oral administration of ethanolic extract causes maximum fall of blood
glucose level to 22.9 % ( p<0.05 ) and 29.4 % ( p<0.01 ) respectively with the two doses in normal and 30.3 % ( p<0.01 ) and 48.4 % ( p<0.001 ) in
diabetic rats . -
pubmed
The standard drug
metformin treated group showed 28.0 % ( p<0.01 ) and 45.5 % ( p<0.001 ) respectively in normal and
diabetic rats . -
pubmed
harmala is as effective as
metformin in reducing the blood
glucose levels of normoglycemic and
streptozotocin - induced
diabetic rats . -
pubmed
METHODS : A total of 74
patients with
acne and of 88 healthy control subjects from Catania , Italy were examined in the present study . -
pubmed
A total of 60 male
rats ( 145 + - 2.52 g ) were grouped into four : A , B , C and D , where group A ( the control ) received 1 mL of distilled water orally while those in groups B , C and D ( test groups ) received orally , same volume of
trona preparation corresponding to 100 , 200 and 400 mg / kg
body weight , respectively , for 28 days . -
pubmed
An outbreak of acute
Schistosoma mansoni Schistosomiasis in a nonendemic area of Brazil : a report on 50 cases , including 5 with severe clinical manifestations . -
pubmed
METHODS : From December 2009 to March 2010 , the 50
patients with acute
schistosomiasis ( group 1 ) bathed in a swimming pool supplied by a brook on a country estate in the outskirts of Sao Joao del Rei , Brazil . -
pubmed
Group 1
patients more frequently had
cercarial dermatitis ( P = .01 ) , blood in the stool ( P = .04 ) , and intra - abdominal lymph nodes ( P = .001 ) . -
pubmed
All group 1
patients were treated with
praziquantel ; 1
patient with
myeloradiculopathy also received oral
prednisone ( 60 mg / day ) for 6 months with complete recovery . -
pubmed
Female C57BL/6
mice underwent
coronary occlusion and reperfusion ; 2 days later , 10(5 ) male
mouse CSCs were injected intramyocardially . -
pubmed
The
strains induced accumulation of
phenolic compounds in
pea leaves and the amount increased when such leaves were get inoculated with
E. - pubmed
Between the two
strains , Pag was found to be more effective than Pf4 as its effect was more persistent in
pea leaves . -
pubmed
The results indicate that GED-0507 - 34L possesses anti - inflammatory properties useful for the management of
patients with
inflammatory skin diseases including
psoriasis . -
pubmed
MATERIAL AND METHODS : In a retrospective study , 25
PC patients , 14
FP patients , and 25
subjects with a normal pancreas underwent breath - hold diffusion - weighted imaging ( DWI ) on a 3.0 T magnetic resonance ( MR ) scanner . -
pubmed
Such effect is more obvious in the
overweight patients . -
pubmed
Estimated
glomerular filtration rate is an easy predictor of
venous thromboembolism in
cancer patients undergoing
platinum - based chemotherapy . -
pubmed
Serum
creatinine and eGFR were evaluated before the start of standard
platinum - based chemotherapy in a cohort of 322 consecutive
patients with primary or relapsing / recurrent
solid cancers , representative of a general practice population . -
pubmed
METHODS : We retrospectively reviewed our experiences with 38
patients with
vaginal agenesis treated with primary surgery from June 2006 to April 2012 . -
pubmed
RESULTS : A total of 38
patients ( 33 with
Mayer - Rokitansky - Kuster - Hauser syndrome and five with
complete androgen insensitivity syndrome ) were included in the present study . -
pubmed
CONCLUSION : Transvestibular vaginoplasty with autologous buccal micromucosa is an effective and feasible approach for
patients with
Mayer - Rokitansky - Kuster - Hauser syndrome and complete
androgen insensitivity syndrome . -
pubmed
Three
patients with
HNF1beta - MODY were found to have
dorsal pancreatic agenesis and four of them had whole - gene deletion . -
pubmed
Calcification of the stylohyoid ligament in panoramic radiography and cone beam computed tomography among
patients referred for dental implant treatment planning . -
pubmed
The objective of this study was to evaluate the incidence of calcified
SHL detected on cone beam computed tomography ( CBCT ) scans and panoramic radiographs ( PR ) in
patients referred for dental implant therapy . -
pubmed
CONCLUSION : CBCT was more accurate in determining the pattern and extent of
calcification of the SHL in
patients undergoing implant treatment planning . -
pubmed
Predictors of failure of conservative treatment among
patients with
emphysematous pyelonephritis . -
pubmed
The aim of this study is to analyze the predictors associated with failure of conservative treatment among
patients with
EPN and offer the recommendation of appropriate empirical antibiotic regimen . -
pubmed
METHODS : From January 2001 to December 2013 , 44 consecutive
patients were diagnosed with
EPN . -
pubmed
Need for emergency hemodialysis ,
shock on initial presentation , altered mental status , severe
hypoalbuminemia , inappropriate empirical antibiotic treatment and
polymicrobial infections were significantly more common in the
patients who died compared with the survivors . -
pubmed
Even in the
patients treated with percutaneous drainage plus effective antibiotics , failure was still associated with severe
hypoalbuminemia ( p = 0.01 ) . -
pubmed
CONCLUSIONS : Both appropriate empirical antibiotic and percutaneous drainage were essential for
patients with
EPN . -
pubmed
Patients with severe
hypoalbuminemia had a higher risk of conservative treatment failure , and additional management may be required . -
pubmed
These compounds therefore have significant potential for future development of chemotherapeutic agents for
patients suffering from
breast cancers and
parasitic infection . -
pubmed
OBJECTIVE : The complexities of
post - stroke spasticity (
PSS ) , and the resultant difficulties in treating the disability , present a significant challenge to
patients ,
stroke rehabilitation teams , and caregivers . -
pubmed
Reducing the severity of
spasticity and its long - term complications may be facilitated by early intervention , making identification of
stroke patients at high risk for developing
spasticity essential . -
pubmed
The
patients were classified into 3 groups : mild
AP , moderately severe
AP , and severe
AP . -
pubmed
RESULTS : Acute
pancreatitis was considered severe in 16 ( 15 % )
patients , moderately severe in 25 ( 24 % )
patients , and mild in 63 ( 61 % )
patients . -
pubmed
Cardiovascular events are the main cause of morbidity and mortality in
CKD patients . -
pubmed
We have studied the effects of cell communication on
human beta cell function and resistance to
cytotoxicity using the novel
human insulin - secreting cell line 1.1B4 configured as monolayers and pseudoislets . -
pubmed
Thus , this study aims to investigate the direct inhibitory effect of
stachyose on
human colon cancer cells and determine the molecular mechanism underlying this effect . -
pubmed
Vanadium toxicity is a challenging problem to
human and animal health with no entirely understanding cytotoxic mechanisms . -
pubmed
Besides ,
vanadium induced mitochondrial / lysosomal toxic interaction and
vanadium reductive activation mediated by
glutathione in
vanadium toxicity was significantly ( P & lt ; 0.05 ) ameliorated by
Sesamum indicum extracts . -
pubmed
METHODS : Sera from 19
patients with
HCV genotype 1 infection and compensated
cirrhosis who failed to respond to a prior course of
Peg - IFN / RBV were selected at time 0 before starting triple therapy with
boceprevir or
telaprevir . -
pubmed
RESULTS :
Patients baseline characteristics were similar to the well - defined CUPIC cohort ( age ,
HCV subtype , baseline
viremia , and treatment history ) . -
pubmed
Cytotoxic activity of
Macrosolen parasiticus ( L. ) Danser on the growth of
breast cancer cell line (
MCF-7 ) . -
pubmed
, This study was aimed to investigate the anti -
cancer activity of methanolic and aqueous extract of stem of
M. - pubmed
MATERIALS AND METHODS : The extracts were tested in
human breast cancer cell lines in vitro for percentage
cytotoxicity , apoptosis by
acridine orange /
ethidium bromide staining , LD50 and IC50 values after treatment with
M. - pubmed
MAIN OBSERVATIONS : The authors report the clinical , dermoscopic and histopathological features of a
hemosiderotic dermatofibroma mimicking
melanoma in an 85 - year - old
woman . -
pubmed
Here ,
rapamycin mediated apoptosis were investigated in
human retinoblastoma Y79 cells . -
pubmed
Together , all these results illustrated that
rapamycin induced apoptosis in
human retinoblastoma Y79 cells involvement of both intrinsic and extrinsic pathways . -
pubmed
The spreading of an infectious
disease can trigger
human behavior responses to the disease , which in turn plays a crucial role on the spreading of epidemic . -
pubmed
CASE REPORT : An 84 - year - old
woman presented to our ED with a painless acute
vision loss in her right eye . -
pubmed
Here we will review the results , mainly published in the last five years , of unbiased proteomics and peptidomics approaches for biomarker research using biological fluids of
Alzheimer ' s , Parkinson 's and
Amyotrophic Lateral Sclerosis patients . -
pubmed
This systematic review aimed to evaluate the literature on the acquisition- , reconstruction- and analysis parameters of micro - computed tomography ( micro - CT ) for the assessment of
periapical lesions in
rats and
mice , and to illustrate the effect of variation in these parameters . -
pubmed
The PubMed database was searched from 2000 to January 2015 ( English - language publications ) for reports on the use of micro - CT to evaluate
periapical lesions in
rats and
mice . -
pubmed
To illustrate the effect of variations in acquisition- , reconstruction- , and analysis parameters on images of
periapical lesions , micro - CT examination of two hemi - mandibles of
mice , with
periapical lesions around the first molar was undertaken . -
pubmed
Twenty - one studies were identified , which analysed
periapical lesions in
rats or
mice using micro - CT . -
pubmed
There is no defined protocol for acquiring and analysing micro - CT images of
periapical lesions in
rats and
mice . -
pubmed
PURPOSE : Substance use behaviors often emerge during adolescence , and adolescents with
type 1 diabetes (
T1D ) may be at risk for engaging in traditional substance use ( eg ,
alcohol ,
tobacco , and illicit substances ) as well as a unique form of substance use :
insulin misuse . -
pubmed
METHODS : Sixty
adolescents aged 12 to 20 years with
T1D ( n = 60 ) completed surveys on substance use ,
insulin misuse , and
diabetes self - management during a routine diabetes appointment . -
pubmed
Analgesic effect of repetitive transcranial magnetic stimulation ( rTMS ) in
patients with
chronic low back pain . -
pubmed
The objective of the present study was to assess the benefits of 1 - week repetitive transcranial magnetic stimulation ( rTMS ) in
patients with
chronic low back pain (
LBP ) . -
pubmed
Eighty - two
patients diagnosed with
LBP were divided randomly into three groups : rTMS - treated group , sham group , and physical therapy - treated group . -
pubmed
Moreover ,
patients who received rTMS had a lower mean
pain score than
patients treated with physical therapy . -
pubmed
Our study suggests that rTMS produces safe , significant , and long - term relief in
patients with
LBP without evident side effects . -
pubmed
METHODS : A retrospective review of 21 consecutive
patients who underwent diffusion - weighted PROPELLER magnetic resonance imaging ( MRI ) on a 1.5 T MRI scanner prior to primary or revision / second - look surgery for suspected
cholesteatoma from 2009 - 2012 was performed . -
pubmed
KTRs after SOT , however , show higher incidences of
EBV viremia and
PTLD ,
sepsis , and
death from
sepsis . -
pubmed
We recently reported that the number of BM - derived stem cells ( SCs ) increases in
patients with
pancreatic and stomach cancer . -
pubmed
In conclusion , mobilization of SCs in
cancer patients depends on the type of
malignancy and its ability to activate pro - mobilization cascades . -
pubmed
Prognostic Role of Preoperative Serum Lipid Levels in
Patients Undergoing Radical Prostatectomy for Clinically Localized
Prostate Cancer . -
pubmed
BACKGROUND : The prognostic role of preoperative serum lipid levels in
patients undergoing radical prostatectomy ( RP ) for clinically localized
prostate cancer (
PCa ) is unclear . -
pubmed
The aim of the present study was to investigate preoperative serum lipid levels in
patients with clinically localized
PCa undergoing RP and their association with clinicopathological features and oncological outcome . -
pubmed
Recurrence occurred in 49
patients ( 15.4 % ) at a median time of 18 months ( 2 - 51 month ) . -
pubmed
Comparison of dose distribution for
head and neck cancer patients with and without dose painting escalation during radiotherapy realized with tomotherapy unit . -
pubmed
OBJECTIVE : To determine and quantify the percentage dose increase to organs at risk ( OARs ) with multiple - level dose painting ( DP ) for
patients with
head and neck cancer in comparison with standard regimen . -
pubmed
Similarly , the role of diet rich in
polyphenols and
plant polysaccharides in modulating gut bacteria and its impact on
diabetes and
obesity have been the subject of investigation by several research groups . -
pubmed
METHODS : Nine
females performed two 5 - d HA interventions ( controlled
hyperthermia Tre>=38.5 C ) , separated by 7 - wk , during the follicular phase of the menstrual cycle confirmed by plasma concentrations of
17 - beta estradiol and
progesterone . -
pubmed
A total of 71 consecutive
patients with closed Sanders type 2 calcaneal
fractures were enrolled and divided into two groups according to the treatment to which they chose : the EFLIF group and the ORIF group . -
pubmed
BACKGROUND : Bacillus Calmette - Guerin ( BCG ) is the most effective initial intravesical therapy for high - grade
non - muscle invasive bladder cancer , but many
patients still fail . -
pubmed
Patients received maintenance if
recurrence - free . -
pubmed
RESULTS : Fifty - two
patients received treatment with a median
recurrence follow - up of 16.3 months and overall follow - up of 41.8 months . -
pubmed
No
patients had
positive surgical margins or positive lymph nodes . -
pubmed
CONCLUSIONS : In
patients with
non - muscle - invasive bladder cancer with prior BCG failure , quadruple immunotherapy demonstrated good treatment success in some
patients and warrants further evaluation . -
pubmed
We report our experience implementing this haplo - HSCT for high - risk
malignancies in pediatric
patients focusing on the conditioning regimen . -
pubmed
Thus , total body irradiation (
TBI ) based regimen was introduced in the following 10
patients and resulted in engraftment in all
patients . -
pubmed
Compared to
patients conditioned with chemotherapy ,
patients conditioned with
TBI had superior actuarial overall survival ( 66 % vs. 37 % , P = 0.05 ) and event - free survival ( 61 % vs. 33 % , P = 0.04 ) . -
pubmed
Similarly , whole brain concentrations of
GABA were not significantly altered in either knockout
mouse strain at 3 or 18 mo of age , as compared to WT . -
pubmed
OBJECTIVE : This prospective study uses calf bioimpedance spectroscopy ( cBIS ) to guide the attainment of dry weight ( DWcBIS ) in chronic hemodialysis (
HD )
patients . -
pubmed
Twenty - eight
patients ( 25 %
diabetes ) achieved DWcBIS , whereas 32
patients ( 47 %
diabetes ) did not . -
pubmed
Ratios of intradialytic changes in calf normalized resistivity , ECV , and ECV / TBW to ultrafiltration volume were significantly lower in
diabetic than in non - diabetic
patients . -
pubmed
The
atrial conduction disorder in
patients with atrial pacing results in higher incidence of
atrial fibrillation . -
pubmed
Studies have shown that low interatrial septal pacing is superior to right atrial appendage pacing in preventing persistent or permanent
atrial fibrillation in these
patients . -
pubmed
PATIENTS AND METHODS : We describe a 73 - year - old
man with a history of advanced primary
open - angle glaucoma who had previously undergone an unsuccessful micropulse transcleral cyclophotocoagulation of the left eye . -
pubmed
Vitamin D deficiency was more common in children older than 1 years than in
children aged 1 year or younger , and
vitamin D deficiency was 2 72 times more likely in girls than in boys ( 95 % CI 1 21 - 6 01 ; p=0 037 ) . -
pubmed
Approximately 20 to 40 % of
patients with type 1 or
type 2 diabetes develop
diabetic kidney disease . -
pubmed
Regular , systematic screening for
diabetic kidney disease is needed to identify
patients at risk for , or with presymptomatic stages of
diabetic kidney disease . -
pubmed
In this article , a
patient having otologic symptoms as a result of spontaneous
herniation of TMJ into
EAC was presented in the light of current literature . -
pubmed
Previously we validated a challenge model that utilized a dose of 2x107 CFU of
ETEC strain H10407 ( LT+ , ST+ , CFA / I+ and O78 + ) to induce attack rates for moderate to severe
diarrhea (
MSD ) of ~60 - 70 % . -
pubmed
Cognitive Profile of
Children With
Intracranial Germ Cell Tumor According to
Tumor Location . -
pubmed
PURPOSE : The purpose of this study was to evaluate the long - term cognitive sequelae and to describe the neuropsychological profile of
patients with
intracranial germ cell tumors according to
tumor location ( pineal or suprasellar site ) . -
pubmed
CONCLUSIONS : Overall cognitive abilities were preserved in
children treated for
central nervous system germ cell tumor . -
pubmed
Eyes were grouped as non - diabetic controls ( 37 eyes ) ,
patients with
diabetes mellitus (
DM ) without
diabetic retinopathy (
DM without
DR , 31 eyes ) ,
non - proliferative diabetic retinopathy (
NPDR , 41 eyes ) and
proliferative diabetic retinopathy (
PDR , 27 eyes ) . -
pubmed
These findings are consistent with previous observations in anesthetized
dogs and indicate that the prokinetic effects of
LMN - NKA may be achieved without
hypotension using a route of administration that avoids unnecessarily high plasma exposures . -
pubmed
BACKGROUND :
Human infection of avian influenza virus ( AIV ) remains a great concern . -
pubmed
Although live poultry markets are believed to be associated with
human infections , ever more
infections have been reported in rural areas with backyard poultry , especially in the fifth epidemic of H7N9 . -
pubmed
First , minimally invasive heart rate ( fH ) measurements were made during a thermal ramp until
cardiac failure in
C. - pubmed
Salmonella Enteritidis became the main serovar isolated from
gastroenteritis cases in Brazil after the 90 's . -
pubmed
In conclusion , our results showed that the genomic profile of
Salmonella Enteritidis strains isolated in Brazil shifted after 1994 , replaced by a global epidemic group of
strains . -
pubmed
It may be hypothesized that the presence of the prophage SE20 might have conferred to these
strains a better ability to colonize
chicken and consequently to infect and cause disease in
humans , which might better explain the increase in the number of
S . - pubmed
Effects of the Problem Solving Technique in Type 2 Diabetic
Patients with
Cognitive Impairment : A Randomized Clinical Trial . -
pubmed
This study aimed to evaluate the effects of problem - solving technique in
type 2 diabetic patients with
cognitive impairment . -
pubmed
96
type 2 diabetic patients with
cognitive impairment were randomly divided into two groups . -
pubmed
Conclusion : Applying problem - solving technique significantly enhanced self - management , quality of life and metabolic indexes in
type 2 diabetic patients with
cognitive impairment . -
pubmed
Clinical significance of radiological
pleuroparenchymal fibroelastosis pattern in
interstitial lung disease patients registered for lung transplantation : a retrospective cohort study . -
pubmed
This study evaluated the clinical significance of radiological
PPFE as an isolated finding or associated with other
interstitial lung diseases (
ILDs ) in
patients having
fibrotic ILDs and registered for cadaveric lung transplantation ( LT ) . -
pubmed
METHODS : This retrospective study included 118
fibrotic ILD patients registered for LT . -
pubmed
Objective : To assess the usefulness of modified esophagogastroduodenoscopy ( EGD ) for the detection of second primary
malignancies of the esophagus or hypopharynx in
patients with
oral squamous cell carcinoma and determine the association between the oral lesion subsite and
esophageal or hypopharyngeal lesion occurrence . -
pubmed
Methods : In total , 166
patients with
oral squamous cell carcinoma without any established symptoms of
esophageal or hypopharyngeal squamous cell carcinoma underwent modified EGD based on the Valsalva maneuver and U - turn method , image - enhanced endoscopy , and chromoendoscopy using
Lugol ' s iodine for diagnosis . -
pubmed
Conclusions : Modified EGD is an effective noninvasive technique for early diagnosis and treatment of second primary
malignancies of the esophagus and hypopharynx in
patients with
oral squamous cell carcinoma . -
pubmed
High expression of miR-665 exhibited more severe
tumor size ,
vascular invasion and Edmondson grading in
HCC patients . -
pubmed
The use of gene expression to unravel the single and mixture
toxicity of
abamectin and
difenoconazole on survival and reproduction of the springtail
Folsomia candida . -
pubmed
The aim of the present study was to evaluate the single and binary mixture
toxicity of commercial products of
abamectin (
Kraft 36 EC ) and
difenoconazole ( Score 250 EC ) to
Folsomia candida . -
pubmed
To investigate
brain abnormalities in
adolescents with new - onset
bipolar disorder (
BD ) during acute
hypomanic and
depressive episodes using electroencephalogram ( EEG ) analysis and to derive a computer - based method for diagnosis of the disorder . -
pubmed
METHODS : During CLARINET ,
patients with metastatic intestinal /
pancreatic NETs received
lanreotide depot / autogel 120 mg or placebo every 4 weeks for 96 weeks . -
pubmed
Treatment of severe
ventriculitis caused by extensively drug - resistant
Acinetobacter baumannii by intraventricular lavage and administration of
colistin . -
pubmed
All patients underwent neurosurgery before
infection , and all
A. - pubmed
Of the 20
patients who were cured , eight underwent shunt surgery due to
hydrocephalus before they were discharged to a rehabilitation center . -
pubmed
Five
patients died , including one who was re - admitted due to
recurrence 1 month after discharge . -
pubmed
Conclusions : IVT lavage and
colistin treatment may be an effective treatment for
SV caused by extensively drug - resistant
A. - pubmed
Combining these two modes of action has been shown to improve
glucose and lipid metabolism , and to improve the overall cardiovascular risk in
patients with
Type 2 diabetes . -
pubmed
The purpose of this review is to evaluate the clinical data that has been published on this combination , appearing to represent a convenient way to obtain therapeutic targets in
patients with
Type 2 diabetes mellitus . -
pubmed
It is prudent to include
metabolic disorders in the differential diagnosis because in some cases , gastrointestinal symptoms may be the only presenting feature in a
patient with an underlying
IEM . -
pubmed
Aim To describe a therapeutic approach , indications for abdominoperineal resection ( APR ) , survival and oncological results for
patients who received treatment in our surgical clinic for
anal canal squamous cell cancer (
SCC ) . -
pubmed
Results Eighteen
patients with
anal canal SCC were included in the study ; 11 ( 61.1 % )
patients were in Group 1 and 7 ( 38.8 % ) in Group 2 . -
pubmed
Early surgical intervention and cessation of
seizure activity are important for
children with intractable
epilepsy . -
pubmed
This paper reviews the
seizure and cognitive outcomes of
epilepsy surgery for
FCD in
children . -
pubmed
CASE REPORT : A 72 - year - old male
patient presented to the emergency department with a 10 - day history of generalized
rash , generalized
muscle and joint pain and
high fever . -
pubmed
The
patient responded rapidly to
corticosteroids and the
skin lesions improved . -
pubmed
RESULTS : Of 132
patients , 41 ( 31.1 % ) developed
POD . -
pubmed
Administration of
Asian Herb Bennet (
Geum japonicum ) Extract Reverses
Depressive - Like Behaviors in
Mouse Model of
Depression Induced by
Corticosterone . -
pubmed
Geum japonicum , commonly known as
Asian herb bennet , has been used as a diuretic , astringent , anti -
dizziness , and anti -
headache agent in traditional medicine . -
pubmed
japonicum extract using
depressive - like behavior induced in
mice through daily injection of
corticosterone (
CORT ) . -
pubmed
We report a case of a
man with
Castleman disease and
monoclonal gammopathy , with a history of
chronic diarrhoea and
asthenia . -
pubmed
Frequently , these
patients present
fatigue ,
weight loss and
sarcopenia with reduction of performance status , limiting subsequent therapeutic options . -
pubmed
BACKGROUND : The ongoing threat of the new coronavirus
SARS - CoV2 pandemic is alarming and strategies for combating
infection are highly desired . -
pubmed
Antihyperglycemic properties of
hydroxychloroquine in
patients with
diabetes : Risks and benefits at the time of COVID-19 pandemic . -
pubmed
Preliminary studies have shown the safety and efficacy of
HCQ ( at a dose ranging from 400 to 600 mg / day ) in
patients with
type 2 diabetes over a short - term period . -
pubmed
In 2014 ,
HCQ has been approved in India as an add - on hypoglycemic agent for
patients with uncontrolled
type 2 diabetes . -
pubmed
However , large randomized controlled trials are needed to establish the safety and efficacy profile of
HCQ in
patients with
type 2 diabetes over a long - term period . -
pubmed
The aim of this manuscript is to comprehensively summarize the current knowledge on the antihyperglycemic properties of
HCQ and to critically evaluate the potential risks and benefits related to
HCQ use in
patients with
diabetes , even in light of the current pandemic scenario . -
pubmed
Promising signs for tackling
bovine TB . -
pubmed
ADVL1522 : A phase 2 study of lorvotuzumab mertansine (
IMGN901 ) in
children with relapsed or refractory
wilms tumor ,
rhabdomyosarcoma ,
neuroblastoma ,
pleuropulmonary blastoma ,
malignant peripheral nerve sheath tumor , or
synovial sarcoma - A
Children 's Oncology Group study . -
pubmed
METHODS : Eligible
patients had relapsed after or progressed on standard therapy for their
tumor type . -
pubmed
One
patient with
rhabdomyosarcoma had a partial response , and 1
patient with
synovial sarcoma achieved a delayed complete response . -
pubmed
Reproductive Diseases in Farmed
Rabbit Does . -
pubmed
In this case , the median of the prevalence of apparent
infertility was 14.5 % ( minimum to maximum : 4.1 - 50 % ) , which could be considered baseline occurrence when monitoring the theriogenology of
rabbit doe farms . -
pubmed
Of these , 3 studies have shown that
vitamin D supplementation does not alter glycemic control markers in pre -
diabetic individuals . -
pubmed
Methods : We reviewed the data of 3,612
patients with
breast cancer treated with radiotherapy ( RT ) between January 2010 and December 2016 . -
pubmed
Clinical outcomes of
hyperbaric oxygen therapy in treatment of postoperative chronic
Pseudomonas aeruginosa wound infection following implant reconstruction of the breast . -
pubmed
Emotional disorders induced by MA abuse have been widely reported both in
human and
animal models ; however , the mechanisms underlying such disorders have not yet been fully elucidated . -
pubmed
In this study , a chronic
MA administration
mouse model was utilized to elucidate the serotonergic pathway involved in
MA - induced
emotional disorders . -
pubmed
After 4 weeks of
MA administration , the
animals exhibited significantly increased
depressive and
anxious symptoms . -
pubmed
We describe a
patient with severe
head injury who deteriorated three weeks after
trauma due to late development of
ventricular septal rupture . -
pubmed
Cyclacillin was compared with
ampicillin by its bacteriostatic efficiency in vitro , chemotherapeutic efficiency in experimental
infections of
mice and
rats and pharmacokinetic characteristics . -
pubmed
[ Restoration of sexual function in latent
ketosis in
cows ] . -
pubmed
[
Hydrocortisone for the treatment of
cerebral vasopasm--(1 ) experiments in
dogs ( author 's transl ) ] . -
pubmed
Psychomotor skills in
depressed out -
patients treated with
L - tryptophan ,
doxepin , or
chlorimipramine . -
pubmed
Psychomotor skills were measured in
depressed out -
patients during three - week double - blind treatment with
1 - tryptophan ( 16
patients ; 0.5 - -1.0 g t.i.d . ) -
pubmed
The effect of
depression on psychomotor skills was evaluated by comparing the results from the pre - drug scores ( 29
patients ) with the respective performances of a matched reference group ( 20 healthy
volunteers ) . -
pubmed
The comparative ventilatory responsiveness to
CO2 was studied in 13 chronic
bronchitics and 14 emphysematous
patients , all exhibiting
respiratory insufficiency and with FEV1 less than 1,500 ml . -
pubmed
parvum to both intact and thymectomized
mice resulted in the appearance in the peritoneal exudate of cells which inhibited
tumour growth in vitro . -
pubmed
This study was performed to investigated the relationship between cross sectional areas of glomerular arterioles and glomerular volume in
rats with
puromycin aminonucleoside (
PAN)-induced
nephrosis , which is an experimental model of
glomerular sclerosis . -
pubmed
A phagocytic assay performed with
human peripheral mononuclear cells and
malaria - infected erythrocytes enabled the study of opsonizing antibodies in
human serum from donors presenting different levels of protective immunity . -
pubmed
Serum
hepatitis C virus sequences in posttransfusion non - A ,
non - B hepatitis . -
pubmed
We investigated 17
patients ( 12
males and 5 females , ages 2 to 57 years old ) with posttransfusion non - A ,
non - B hepatitis to determine relationships between clinical courses and
hepatitis C virus (
HCV ) markers . -
pubmed
With respect to clinical course ,
HCV RNA was detected in six of eight patients ( 75 % ) with
chronic biochemical disease , and in two of five patients ( 40 % ) with biochemically resolved
chronic disease . -
pubmed
HCV RNA was not detectable in convalescent sera from four patients with
acute disease . -
pubmed
Thus , PCR is useful in determining the persistence of
HCV infection as well as to diagnose
anti - HCV negative
HCV infection . -
pubmed
[ Anesthesiologic management of surgery of the aorta and the major vessels in
patients with
diabetes mellitus ] . -
pubmed
In 23
patients with
diabetes mellitus , the effectiveness of anesthesiologic support of the operations on the aorta and major vessels , which was based on combined epidural anesthesia performed using the conventional technique , was analysed . -
pubmed
Pharmacokinetics of
cefprozil in healthy subjects and
patients with
hepatic impairment . -
pubmed
The pharmacokinetics of
cefprozil were studied in 12 ( 9
men , 3
women )
subjects with
hepatic impairment and in 12 healthy
subjects who were matched for age , sex , and weight . -
pubmed
The values for the peak plasma concentrations ( Cmax ) , area under the plasma concentration versus time curve ( AUC0 - infinity ) , apparent total body clearance ( Clt / F ) , renal clearance ( Clr ) , and percent of drug excreted in urine ( % UR ) of each isomer were not significantly different in healthy subjects and
patients with
hepatic impairment . -
pubmed
The only parameters that were significantly ( P less than or equal to .05 ) longer in
patients with
hepatic impairment were mean residence time in the body ( MRT ) and half - life ; the MRT for the
cis isomer in healthy
subjects and
subjects with
hepatic impairment were 3.33 hr and 3.88 hr , respectively , and for the trans isomer 3.17 hr and 3.68 hr ; the half - life for the
cis isomer was 1.62 hr and 2.22 hr , respectively , and for the trans isomer 1.21 hr and 1.54 hr . -
pubmed
The pharmacokinetics of the cis and trans isomers of
cefprozil were virtually identical in healthy
subjects as well as those with
hepatic impairment . -
pubmed
The authors retrospectively analyzed 51
morphine - augmented hepatobiliary studies performed in a tertiary referral center on a population with a high proportion of severe intercurrent illness ( 18
patients , 14 of whom were receiving total parenteral nutrition ) and
hepatocellular dysfunction ( eight
patients ) . -
pubmed
Four
patients developed recurrent vascular graft
thrombosis while receiving anticoagulation . -
pubmed
Patients with a chronic risk for arterial or
venous thrombosis can have out -
patient anticoagulant therapy administered at optimal intensity and regulated safely with a low incidence of
hemorrhagic and
thrombotic events . -
pubmed
All three
patients were suffering from
malabsorption when
TPN was instituted , and overt symptoms of
copper deficiency developed an average of 5.8 months after the start of
TPN . -
pubmed
Numerous metabolic parameters in serum and urine were examined in 110
cataract patients before and after
cataract surgery . -
pubmed
In addition , an " energetic action " of the light affecting the hypothalamus via the retino - hypothalamic pathways ( the " energetic portion " of the visual pathway ) was proved in
patients who were blinded by
cataract and had
metabolic disturbances as a result . -
pubmed
Postoperatively , after elimination of the
lens opacities , the metabolism and hormones of the same
patients returned to normal . -
pubmed
These comparative investigations in the same
patients before and after
cataract extraction provide for the first time irrefutable scientific evidence of the influence of light via the eye on the
human organism . -
pubmed
Long - term followup in 1,003 extracorporeal
shock wave lithotripsy
patients . -
pubmed
We evaluated 1,003
patients treated with extracorporeal
shock wave lithotripsy after a mean followup of 19.1 months ( range 12 to 26 months ) . -
pubmed
Patients with lower
caliceal stones had a rate without
calculi of only 57.8 per cent . -
pubmed
Phaeohyphomycotic cyst caused by a recently described species ,
Phaeoannellomyces elegans . -
pubmed
Eleven
patients with
ureteric transitional cell tumours were reviewed and conservative management recommended . -
pubmed
Smoking habits were analysed in 114
patients with
subarachnoid haemorrhage , less than 70 years old , obtained from an epidemiological study . -
pubmed
Effects of scheduled food and water deprivation on food intake , water intake and
body weight of cage - adapted and cage - naive
rats . -
pubmed
The first experiment examined the effects of four food - deprivation schedules and four water - deprivation schedules on
body weight , food intake and water intake of adult
rats over ten days of deprivation and two days of recovery . -
pubmed
Bronchial hyperreactivity was confirmed in eleven nonselected
patients with chronic
respiratory disease during a period of quiescence by inhalative provocation with
histamine . -
pubmed
After one week 's treatment with
ketotifen a protective effect against the
histamine - induced
bronchospasm was observed in nine
patients . -
pubmed
The rapid appearance of this protective mechanism was demonstrated both in
patients with exogenous and endogenous
bronchial asthma and in the three
patients with
chronic bronchitis . -
pubmed
In vivo P - NMR spectroscopy : muscle energy exchange in
paramyotonia patients . -
pubmed
Using
phosphorus nuclear magnetic resonance spectroscopy , we studied the muscle metabolism in four
patients with
paramyotonia congenita as reflected in the PC / Pi and PC /
ATP ratios . -
pubmed
Pain in the lower limb was the predominant symptom in forty - eight
patients . -
pubmed
Reduction of the amount of straight leg - raising by 50 per cent or more , with or without
pain in the ipsilateral hip when the asymptomatic limb was lifted ( cross - over
pain ) and with or without
pain radiating up or down the lower limb when the tibial nerve was pressed in the popliteal fossa (
bowstring discomfort ) , was considered evidence of tension on or irritation of the nerve root and was present in all
patients . -
pubmed
An
anaphylactic reaction occurred in one
patient and was treated successfully . -
pubmed
One
patient had transient
weakness of the extensor hallucis longus after injection . -
pubmed
The potential role of
cats in the epidemiology of
Toxoplasma gondii infections . -
pubmed
The role of perceived versus actual attack in
human physical
aggression . -
pubmed
[ Evaluation of the excretory function of the liver in
patients with
rheumatic heart disease and
circulatory insufficiency ] . -
pubmed
Drug toxicity in the
human fetus and newborn child . -
pubmed
Adult
patients with
bacterial infections of the lower respiratory tract were given either
cefoperazone or
cefamandole in a multicenter clinical study of the clinical and bacteriologic efficacy of
cefoperazone . -
pubmed
The results of this study indicate that
cefoperazone is a safe and effective antibiotic for the treatment of lower
respiratory tract infections due to
S. - pubmed
aureus , and many gram - negative bacilli , including susceptible
strains of
P. - pubmed
The problem of
human geohelminthoses and the prospects for their biological control . -
pubmed
The clinical effectiveness of immunotherapy with the cell wall skeleton of
Bacillus Calmette - Guerin was assessed in a study involving 140 consecutive
patients with
gastric cancer , who were gastrectomized at a single institution from January 1976 through December 1978 . -
pubmed
These results emphasize effectiveness of BCG - CWS as an adjuvant immunotherapeutic agent in gastrectomized
cancer patients . -
pubmed
On the basis of the usual diagnostic criteria , 41 % of the
workers had
asbestosis . -
pubmed
Proper selection of patients for successful penetrating keratoplasty depends on four important factors : ( 1 ) psychosocial factors , including visual need , the conditions under which the patient lives , and the patient 's ability to nurture this tissue over many years ; ( 2 ) the general condition of the eye , including the health of the ocular surface , intraocular pressure , motility , anterior segment anatomy , and
vitreoretinal disease ; ( 3 ) the structure of the host cornea -- in terms of its thickness , vascularization , epithelial and stromal integrity , and sensation -- as well as the corneal condition for which the operation is being done ; and ( 4 ) the skills of the ophthalmologist managing the graft , particularly those involved in preoperative
patient selection and postoperative graft management , as well as his technical surgical skills . -
pubmed
In vitro cytotoxic properties of plasma fractions from
uremic patients . -
pubmed
Uremic plasma were taken from severe
uremic patients ( plasma creat . -
pubmed
greater than 0.45 mM / L ) and from hemodialysed (
HD )
patients : plasma from
HD patients were obtained at the beginning and end of a dialysis session . -
pubmed
The modified tochar epistostomy was performed in 7
children with
hypoplasia subjected to urethroplasty . -
pubmed
Galactosamine - induced cell
death in primary cultures of
rat hepatocytes . -
pubmed
Chlorpromazine given to intact
rats 2 hours after treatment with 400 mg / kg
galactosamine prevented the appearance of liver cell
necrosis . -
pubmed
Biochemical and pathological effects of 8 months of neoadjuvant
androgen withdrawal therapy before radical prostatectomy in
patients with clinically confined
prostate cancer . -
pubmed
MATERIALS AND METHODS : We evaluated 50
patients with clinically localized
prostate cancer treated by 8 months of reversible
androgen ablation before radical prostatectomy . -
pubmed
DESIGN /
PATIENTS : Thirty untreated
patients with
acromegaly were compared with 30 healthy
adults . -
pubmed
In this study we have evaluated psychomotor activity ( PMA ) and passive avoidance behavior ( PAB ) in
rats with bilateral
neurotoxic lesions in the posterior hypothalamic region ( PHR ) ( L ) , where histaminergic neurons are located , and in sham - operated
rats ( S ) , two weeks after neurosurgery . -
pubmed
Role of acid and
duodenogastric reflux in
esophageal mucosal injury : a review of animal and
human studies . -
pubmed
The role of acid and
duodenogastric reflux ( DGR ) in the development of
esophageal mucosal injury has been extensively investigated using both
animal and
human models . -
pubmed
Despite some conflicting results , preliminary
human studies support the results from the
animal data suggesting synergistic damaging effects for both
bile and acid in
esophageal mucosal injury . -
pubmed
Delusions and other manifestations of
psychotic behavior are common side effects in
Parkinson ' s disease (
PD )
patients chronically treated with dopaminergic drugs . -
pubmed
We evaluated the effects of low doses of
clozapine on the mental and motor functions in
PD patients requiring antipsychotic treatment . -
pubmed
Twenty - seven
PD patients taking dopaminergic drugs and who had
psychotic behavior received
clozapine at 12.5 to 75 mg / d. Fifteen
patients received
clozapine for 1 to 11 months ( mean , 6.8 months ) and seven received it for 12 to 24 months ( mean , 18 months ) . -
pubmed
No
patient exhibited motor deterioration , and the
psychotic features disappeared immediately , allowing discontinuation of
clozapine after several months in 10
patients . -
pubmed
Fifteen
patients are still receiving
clozapine and are free of
psychiatric symptoms . -
pubmed
The
clozapine treatment was discontinued after 5 days ( 25 mg / d ) in two
patients because of
somnolence . -
pubmed
No
patient developed
neutropenia . -
pubmed
We report 3
patients in whom intraoperative transesophageal echocardiography was used for precise localization of the fistulous drainage site , selective demonstration of vessels feeding the
fistulas , and documentation of abolition of fistulous flow , all without need for cardiopulmonary bypass . -
pubmed
The
patient 's symptoms resolved quickly , and a repeat venogram 16 hours later showed near - complete resolution of the
venous obstruction . -
pubmed
Transmetatarsal amputation for
infection or
gangrene in
patients with
diabetes mellitus . -
pubmed
Immediate effects of lung transplantation on right ventricular morphology and function in
patients with variable degrees of
pulmonary hypertension . -
pubmed
OBJECTIVES : This study sought to determine the immediate effects of lung transplantation on right ventricular morphology and function in
patients with variable degrees of
pulmonary hypertension and to evaluate these features as potential markers of immediate outcome . -
pubmed
BACKGROUND : Selected lung transplant
recipients with severe preoperative
pulmonary hypertension have previously been shown to have a reduction in right ventricular size and improved function at follow - up evaluation . -
pubmed
METHODS : Thirty - two consecutive
patients ( mean [ + /- SD ] age 44 + /- 11 years ) were prospectively classified into three groups according to their pretransplantation pulmonary artery
systolic pressure : severe
pulmonary hypertensive group & gt ; or = 75 mm Hg , intermediate pulmonary
hypertensive group 40 to 74 mm Hg and non - pulmonary
hypertensive group & lt ; 40 mm Hg . -
pubmed
Three
patients with severe
pulmonary hypertension who had continued depression of right ventricular function after transplantation died in the immediate postoperative period . -
pubmed
Effect of
pyridoxine and
magnesium on stress - induced
gastric ulcers in
mice selected for low or high blood
magnesium levels . -
pubmed
OBJECTIVE : The association between
attention - deficit hyperactivity disorder (
ADHD ) and cigarette smoking in
children and
adolescents was evaluated . -
pubmed
METHOD : Subjects were 6- to 17 - year - old
boys with
DSM - III - R ADHD ( n = 128 ) and non - ADHD comparison
boys ( n = 109 ) followed prospectively for 4 years into mid - adolescence . -
pubmed
Extra- and intracellular localization of advanced glycation end - products in
human atherosclerotic lesions . -
pubmed
Drug administration in
patients with
renal insufficiency . -
pubmed
The general principles to enhance the safety of drug therapy in
patients with
renal insufficiency include knowledge of the potential toxicities and interactions of the therapeutic agent , consideration of possible alternatives therapies and individualisation of drug therapy based on
patient level of renal function . -
pubmed
Although optimisation of the desired therapeutic outcomes are of paramount importance , additional pharmacotherapeutic issues for
patients with
reduced renal function are the prevention or minimisation of future acute or chronic
nephrotoxic insults , as well as the severity and occurrence of adverse effects on other organ systems . -
pubmed
Investigations of prophylactic approaches to enhance the safety of these agents in
patients with
renal insufficiency have yielded inconsistent outcomes . -
pubmed
Operations through small incisions are mostly applied to
patients with less extensive
coronary disease , mostly single - vessel disease . -
pubmed
Upper eyelid entropion is a complication of chronic
blepharoconjunctivitis which may be easily missed unless careful examination of the lid margin of
patients with
trichiasis is carried out . -
pubmed
They are involved in the regulation of proliferation and differentiation , and activating mutations of these genes are commonly associated with
human cancers . -
pubmed
Of these
patients , we know of 3 ( 0.3 % ) who subsequently developed
abscesses as a consequence of dropped stones during the laparoscopic cholecystectomy . -
pubmed
One additional
patient who underwent prior laparoscopic cholecystectomy at another institution developed late
infection as well . -
pubmed
RESULTS : All 4
patients developed late purulent
abscesses that ultimately required open surgical drainage , and 1 patient developed trocar site "
tumor "
masses that were secondary to inflammatory tissue around
gallstone fragments . -
pubmed
DESIGN AND
PATIENTS : Sixteen
patients with persistent anterior instability after recurrent
shoulder dislocations were examined in an open MRI unit ( 0.2 T ) following 0.1 mmol / kg of intravenous
gadodiamide . -
pubmed
In the present study ,
diphtheria toxoid was used as a model antigen primarily due to its weak immunological properties as well as to its importance as a future
human vaccine for mucosal , particularly nasal immunization . -
pubmed
In the present study , we have shown that
mono - olein /
oleic acid vesicles enhance the immunogenicity of admixed
diphtheria toxoid in
mice to the same level as Alum adsorbed ( or Freund 's complete adjuvant ) when administered parenterally or nasally . -
pubmed
Evolution of
insulin resistance in
coronary artery disease patients on four different pharmacological therapies . -
pubmed
The objective of the study was to examine the evolution of
insulin sensitivity in a group of
patients with stable
coronary artery disease receiving one of four different pharmacological therapies . -
pubmed
After 6 months ,
patients treated with
captopril and , to a lesser extent , those treated with
diltiazem showed statistically significantly decreased steady state plasma
glucose concentrations and increased
insulin sensitivity index compared to basal values . -
pubmed
Peripheral lymphocytes were isolated from two
patients with homozygous
familial hypercholesterolemia (
FH ) , one homozygote for the mutation N804 K ( FH(Colmenar ) ) in exon 17 , herein described for the first time , and a compound heterozygote carrying the mutations D280 G and G528V , which determine a transport - defective biochemical phenotype . -
pubmed
N of 1 randomised controlled trials of oral
ketamine in
patients with
chronic pain . -
pubmed
Anecdotal reports suggest that the general anaesthetic drug
ketamine , taken orally in low doses , can give rise to some extra analgesia in
patients with refractory
neuropathic pain . -
pubmed
This study was designed to determine the proportion of
patients with chronic
neuropathic pain responding to oral
ketamine , and then to separate the true treatment effect from non - specific effects by means of an n of 1 randomised controlled trial . -
pubmed
Twenty - one
patients gave informed consent and completed daily
pain diaries and continued on their usual treatments ( drug and non - drug ) for the duration of the study . -
pubmed
Twelve
patients did not progress to the n of 1 trial because of no benefit and/or intolerable adverse effects (
dizziness ,
drowsiness etc . ) -
pubmed
We conclude that oral
ketamine only gave rise to an extra analgesic response in three out of 21
patients with chronic
neuropathic pain ( 14 % ) . -
pubmed
Possible viral triggers are visited here , including
cytomegalovirus in view of increased levels of anti -
CMV antibodies in
scleroderma , and the remarkable similarities between
CMV vasculopathies and
scleroderma vascular disease . -
pubmed
Anti -
tumor promoting effects of
sesquiterpenes from
Maytenus cuzcoina (
Celastraceae ) . -
pubmed
HIV patients are at higher risk of developing
hypertension at a younger age than the general population . -
pubmed
Through selective cultivation using nylon oligomers as a sole source of
carbon and
nitrogen , two
strains which initially had no metabolic activity for nylon oligomers ,
Flavobacterium sp . - pubmed
In order to examine the natural history of
febrile convulsions occurring after 5 years of age , we studied 44
children in whom
febrile convulsions persisted after 5 years of age ( group 1 ) and compared their development of unprovoked
seizures with a group of 195
children in whom
febrile convulsions occurred before 5 years of age ( group 2 ) . -
pubmed
In group 1 , we found a higher percentage of unprovoked
seizures than in
children with
febrile convulsions with onset before 5 years of age ( 18.1 % vs 7.4 % , P & lt ; .05 ) . -
pubmed
Our data suggest that children with
febrile convulsions after 5 years of age probably must be considered as a group of
patients at risk of developing unprovoked
seizures . -
pubmed
[
Scarlet fever and other
infections from
Streptococcus pyogenes ] . -
pubmed
Computed tomography of pulmonary sarcoid - like
granulomas induced by complete Freund 's adjuvant in
rats . -
pubmed
Intravenous injection of complete Freund 's adjuvant ( CFA ) in
rats has been proposed as an experimental model for
pulmonary sarcoidosis , but only some
animals develop
granulomas . -
pubmed
Thus , lung computed tomography appears to be a valuable tool for the in vivo evaluation of the
pulmonary granulomatous reaction induced by complete Freund 's adjuvant in
rats . -
pubmed
Asynchronously occurring bilateral
mandibular hemorrhagic bone cysts in a
patient with
idiopathic thrombocytopenic purpura . -
pubmed
AIMS : To investigate whether intravascular ultrasound provides additional information regarding the prediction of
stent thrombosis , a retrospective multicentre registry was designed to enrol
patients with
stent thrombosis following stent deployment under ultrasound guidance . -
pubmed
METHODS AND RESULTS : A total of 53
patients were enrolled ( mean age 61+/-9 years ) with
stable angina ( 43 % ) ,
unstable angina ( 36 % ) , and
post - infarct angina ( 21 % ) who underwent intracoronary stenting . -
pubmed
A 2.5 - year - old
girl with
acute disseminated encephalomyelitis , who developed bilateral symmetrical lesions in the basal
ganglion , thalamus , corpus callosum , cerebral subcortical white matter , and cerebellar medulla on brain magnetic resonance imaging is described . -
pubmed
No effect of extremely low - frequency magnetic field observed on cell growth or initial response of cell proliferation in
human cancer cell lines . -
pubmed
We , therefore , exposed the five cell lines (
HL-60 ,
K-562 ,
MCF-7 ,
A-375 , and
H4 ) derived from
human tumors to a magnetic field for 3 days to investigate the effects on cell growth . -
pubmed
DESIGN / METHODS : The
infants were aged 25 - 36 weeks of gestation , & lt ; or = 7 days of age , and without sedation or
congenital abnormalities . -
pubmed
and
Acinetobacter lwoffii can be sources of
nosocomial infection . -
pubmed
Pseudomonas aeruginosa is a potentially serious pathogen and is implicated in the aetiology of
otitis externa . -
pubmed
Does direct visualization of peripatch areas in beating heart eliminate the risk of residual
ventricular septal defect in adult
patients ? -
pubmed
Varying susceptibility to
myocardial infarction among C57BL/6
mice of different genetic background . -
pubmed
Genetically manipulated
mouse lines are invaluable to investigate the effects of a single gene on sensitivity to
ischemia . -
pubmed
BACKGROUND : We conducted a phase II study of
vinorelbine and
cisplatin chemotherapy in
non - small cell lung cancer (
NSCLC )
patients who had failed previous chemotherapy , to assess the response and
toxicity of this combination chemotherapy . -
pubmed
Grade 3 or 4
neutropenia occurred in 40.9 % of the
patients , and grade 3 or 4
anemia occurred in 13.6 % of the
patients during treatment . -
pubmed
Uneventful
febrile neutropenia occurred in 1
patient . -
pubmed
CONCLUSIONS :
Vinorelbine and
cisplatin salvage chemotherapy produced a modest anti -
tumor response , a mild toxicity profile , and reasonable survival in our elderly
NSCLC patients with a poor performance status . -
pubmed
This regimen deserves further study in elderly
NSCLC patients who have failed previous chemotherapy . -
pubmed
[ An experiment of gut barrier function damage following multiple
firearm injuries in a
porcine model ] . -
pubmed
OBJECTIVE : To study the characteristics and pathogenesis of
gut barrier damage following multiple
firearm injuries in
porcine models . -
pubmed
METHODS : 24 small
pigs were divided into 4 groups ( n = 6 each ): control group(group C ) , group H ( gunshot - induced tangential
fracture of parietal bone ) , group L ( gunshot - induced comminuted
fracture of bilateral femora ) and group M ( combined group H + L ) . -
pubmed
The damage of gut barriers in
multiple traumas were more severe than that in one - site
trauma , which enhanced the incidence of intestinal endotoxin and
bacterial translocation and trend to cause
enterogenous infection . -
pubmed
The first patient was a 65 - year - old
woman in whom a
carcinoid tumor of the distal bile duct was incidentally found during an open cholecystectomy for
cholecystitis . -
pubmed
The second patient was a 27 - year - old
man in whom a
distal common bile duct carcinoid was incidentally found during orthotopic liver transplantation for
sclerosing cholangitis and multiple
biliary strictures . -
pubmed
On the immunological inhibition of transplantation of a
carcinoma of
mouse . -
pubmed
PARTICIPANTS : 120
adults taking
simvastatin or
atorvastatin after cardiac surgery or
myocardial infarction . -
pubmed
OBJECTIVES : To assess survival and long term arch patency rates in a consecutive group of
children after extended arch repair for
coarctation of the aorta . -
pubmed
For assessment of survival
patients were divided into three groups : 1 ,
coarctation alone , n = 104 ; 2 , coarctation and
ventricular septal defect , n = 38 ; and 3 ,
coarctation in association with complex
intracardiac anomalies , n = 49 . -
pubmed
Arch obstruction recurred in seven of 165 ( 4.2 % )
patients : four of 139 ( 2.9 % ) term and three of 10 ( 30 % ) premature infants ( p & lt ; 0.001 ) . -
pubmed
Fructose variation in the
dengue vector ,
Aedes aegypti , during high and low transmission seasons in the Mae Sot region of Thailand . -
pubmed
To understand the potential for facultative
sugar feeding by
Aedes aegypti , an important vector of
dengue viruses , we evaluated seasonal and villagewide variation in
sugar feeding during high- and low -
dengue transmission seasons ( rainy and dry seasons , respectively ) in the Mae Sot region of Thailand . -
pubmed
METHODS : Totally 319
patients with
hypertension were investigated for their QOL in comparison with 319 healthy controls using the World Health Organization Quality of Life assessment instrument ( WHOQOL-100 ) . -
pubmed
CONCLUSION : Improvement of the
hypertensive patients ' QOL in addition to effective blood pressure control is a basic target in clinical therapy of
hypertension . -
pubmed
PARTICIPANTS : Three hundred ninety - seven
patients with upper respiratory symptoms of the
common cold . -
pubmed
CONCLUSION : This homeopathic treatment may be a useful component of an integrated symptomatic therapy for the common
cold in
patients and practitioners choosing an integrative approach to medical care . -
pubmed
BACKGROUND : Chronic
hip pain is often a debilitating problem and many
patients are not good surgical candidates . -
pubmed
METHODS : This is a case series of 4
patients who had anterior and or medial
hip pain who underwent percutaneous radiofrequency lesioning of the sensory branches of the obturator and femoral nerves . -
pubmed
RESULTS : All four
patients had reduction in
pain , while 3 of 4
patients had improved functioning . -
pubmed
Two of the four
patients had decreased use of their
pain medication . -
pubmed
One of the four
patients reported
numbness at the hip and there were no other side effects . -
pubmed
PATIENTS : Forty - nine
adults undergoing bone marrow transplantation for
hematologic malignancies or
metastatic solid tumors . -
pubmed
INTERVENTION : Twenty - four
patients received
heparin and 25 received lepirudin
flushes . -
pubmed
After 3 - 4 weeks , all 49
patients received the
heparin flushes . -
pubmed
CONTEXT : Despite a stage - shift to earlier
cancer stages and lower
tumor volumes for
prostate cancer , pathologically advanced disease is detected at radical prostatectomy in 38 % to 52 % of
patients . -
pubmed
Patients were 425
men with pathologically advanced
prostate cancer who had undergone radical prostatectomy . -
pubmed
For
metastasis - free survival , 76 ( 35.5 % ) of 214
men in the adjuvant radiotherapy group were diagnosed with metastatic
disease or died ( median
metastasis - free estimate , 14.7 years ) , compared with 91 ( 43.1 % ) of 211 ( median
metastasis - free estimate , 13.2 years ) of those in the observation group ( hazard ratio [ HR ] , 0.75 ; 95 % CI , 0.55 - 1.02 ; P = .06 ) . -
pubmed
A 67 year old
man presented with new - onset
atrial flutter . -
pubmed
Effectiveness of arterial embolization procedure in
uterine cancer patients . -
pubmed
Patients with late stage
gynecologic malignancies occasionally develop massive
pelvic hemorrhage , and management of the
hemorrhage is often difficult . -
pubmed
Transcatheter arterial embolization with an absorbable
gelatin sponge following the Seldinger method was performed to control
hemorrhage in five
patients with
cancer of the uterine cervix . -
pubmed
Pelvic arteriograms of five
patients showed no further extravasation and their
bleeding ceased . -
pubmed
Based on these findings , this therapeutic embolization method proved to be useful in the management of massive
pelvic hemorrhage in
patients with
cervical cancer . -
pubmed
OBJECTIVE : To assess the effect of repeated application and removal of adhesive edges from
wound - care products on cutaneous irritancy and barrier function in normal
volunteer subjects . -
pubmed
Adhesive edges from six commonly used
wound - care products were applied continuously to the same site ( six applications over a 14 - day period ) in 30 normal
volunteer subjects . -
pubmed
Most of the research has suggested that these changes , at least in the majority of
individuals , occur only at a very advanced stage ; however , those conditions that are treatable and potentially reversible are acute in onset and often associated with acute
confusional states . -
pubmed
Therefore , physicians should be aware of the possibility of reversible causes of cognitive change in their elderly
patients , including certain medications responsible for
memory loss and other organ system diseases . -
pubmed
In addition , the authors stress that not all
memory loss in geriatric
patients is due to
Alzheimer ' s disease and that when history and physical examination provide evidence of
hypertension and magnetic resonance imaging provides evidence of
leukoaraiosis , a diagnosis of
vascular dementia should be considered . -
pubmed
However once diagnosis is made and
haematoma removed , it gives good symptomatic relief to the
patient . -
pubmed
Isolates of
Clostridium perfringens type D produce the potent epsilon - toxin ( a CDC / U.S. Department of Agriculture overlap class B select agent ) and are responsible for several economically significant
enterotoxemias of domestic livestock . -
pubmed
PATIENTS / METHODS : Ten
patients with
PG were treated with IVIG at Johns Hopkins Department of Dermatology . -
pubmed
Five
patients complained of
nausea with treatment , and in one case
nausea was severe and intractable . -
pubmed
One
patient developed an immune reaction requiring
diphenhydramine and
methylprednisolone and another experienced
aseptic meningitis . -
pubmed
Pustular psoriasis - like
tinea incognito due to
Trichophyton rubrum . -
pubmed
We describe an 11 - year - old
girl who presented with widespread
erythematous and pustular lesions being treated with topical
corticosteroid . -
pubmed
Combining metabolic engineering and metabolic evolution to develop nonrecombinant
strains of
Escherichia coli C that produce
succinate and
malate . -
pubmed
Pregnancy complications were chronic
hypertension in 21
patients ( 40 % ) ,
anemia in 28 ( 52.6 % ) , and
urinary tract infection in 18 ( 34 % ) . -
pubmed
Three
patients ( 5.6 % ) had graft losses as a result of
hemorrhagic shock ,
sepsis , and
eclampsia . -
pubmed
Cesarean section was performed in 24
patients ( 45.2 % ) , the main indications being related to
hypertension and
fetal distress . -
pubmed
Effect of
trans-2,3 - dimethoxycinnamoyl azide on enhancing antitumor activity of
romidepsin on
human bladder cancer . -
pubmed
A
PEG tube for enteral feeding was placed in a 27 - year - old
man with cerebral plasty and a severe
scoliosis . -
pubmed
UNLABELLED : The aim of the present study was to retrospectively re - evaluate a population of selected infants with
congenital hypothyroidism (
CH ) , in order to investigate whether sexual dimorphism affects : a ) CH etiology ; b ) its biochemical severity at the time of screening and recall ; c )
patients ' biochemical response to replacement treatment during the 1st yr of life ; d ) their bone maturation ( BM ) at birth ; e ) their psychomotor status at 1 yr . -
pubmed
Thirty
boys ( 39.5 % ) and 66 girls ( 56.9 % ) were found to have
ectopia , whereas the remaining 46 boys and 50 girls exhibited the other causes of
CH . -
pubmed
Failure to develop
multiple sclerosis in
patients with
neurologic symptoms without objective evidence . -
pubmed
BACKGROUND : Many
patients referred to
multiple sclerosis (
MS ) centers with symptoms suggestive of
MS are found to have normal neurologic examinations , normal or non - specific brain magnetic resonance imaging ( MRI ) scan findings , and normal cerebrospinal fluid ( CSF ) . -
pubmed
We performed a study to evaluate the diagnostic utility of repeated evaluations in
patients with normal initial assessments and persistent
neurologic symptoms . -
pubmed
No
patients at initial presentation or at follow - up fulfilled diagnostic criteria for
MS . -
pubmed
BACKGROUND :
Infection with
Helicobacter pylori (
H. - pubmed
These results strongly suggest that
HCV infection cured in
patients who achieve an SVR . -
pubmed
Ischemic cerebrovascular events in
patients with
Chagas cardiomyopathy : a prospective follow - up study . -
pubmed
The aims of this study were to describe the incidence and to evaluate the effect of LV ejection fraction on the risk for ICE in
patients with
Chagas cardiomyopathy . -
pubmed
METHODS : A total of 213 consecutive
patients with
Chagas disease and
LV systolic dysfunction , 131
males , mean age 48+/-12 years , were prospectively enrolled . -
pubmed
CONCLUSIONS : In
patients with
Chagas cardiomyopathy , the annual incidence of ICE is low . -
pubmed
Influence of lean body mass on cardiopulmonary repercussions during the six - minute walk test in
patients with
COPD . -
pubmed
The objective of this study was to analyze the cardiopulmonary variables in
COPD patients with or without LBM depletion , prior to and after the six - minute walk test ( 6MWT ) . -
pubmed
METHODS : We evaluated
COPD patients , 32 with
LBM depletion and 36 without . -
pubmed
All
patients underwent clinical evaluation , spirometry , evaluation of body mass composition and 6MWT , as well as completing questionnaires related to quality of life and perception of
dyspnea . -
pubmed
The distance covered on the 6MWT was similar in
COPD patients with and without LBM depletion ( 470.3 + /- 68.5 m vs. 448.2 + /- 89.2 m ) . -
pubmed
However ,
patients with LBM depletion presented significantly greater differences between baseline and final values in terms of heart rate and Borg scale index for
lower limb fatigue . -
pubmed
However , the
patients with LBM depletion presented more pronounced
lower limb fatigue during the 6MWT , which underscores the importance of the evaluation and treatment of systemic manifestations in
COPD patients . -
pubmed
Several
animal models have been developed to assist in determining efficacy of immunosuppression in
AIED , and several clinical studies have also investigated the role of both
steroid and
steroid - sparing treatments . -
pubmed
Here , the repetitive division pattern of cambial initials in
Populus nigra ' italica ' was studied to follow the development of the
PD network during maturation . -
pubmed
We report a case of a
patient who developed
DIIHA caused by 2 drugs . -
pubmed
In this study , we found that F13 greatly inhibited cell proliferation in various
human cancer cells . -
pubmed
OBJECTIVE : To determine the incidence of early
postoperative complications in
patients undergoing cervical spine surgery and its correlation with preoperative diagnosis . -
pubmed
METHODS :
Patients with
supratentorial tumors undergoing elective craniotomy for
tumor resection under standard anesthesia underwent cerebral autoregulation and
CO2 reactivity testing immediately before and between 6 and 24 hours after surgery . -
pubmed
However , cerebral autoregulation was impaired preoperatively in 7 ( 20 % )
patients and remained impaired in all 7
patients after
tumor resection . -
pubmed
CONCLUSION : Preoperative cerebral autoregulation was impaired in a significant number of
patients with large supratentorial
tumor size and midline shift more than 5 mm and was associated with postoperative
impaired cerebral autoregulation during the first 24 hours after the surgery . -
pubmed
Bariatric surgery for
type 2 diabetes : weighing the impact for
obese patients . -
pubmed
Bariatric surgery results in significant
weight loss and remission of
diabetes in most
patients . -
pubmed
CLINICAL CASE : We present the cases of two
patients with
ISCH who were misdiagnosed and operated on in other spinal segments without reaching an accurate diagnosis . -
pubmed
Treatment may allow recovery of the
neurological deficit , improving motor affection in 80 % of
patients and sensory affection in 35 % . -
pubmed
MATERIALS AND METHODS : This study was carried out in 30
patients in the age group 10 - 14 years with bilateral
carious permanent first molars . -
pubmed
The present study investigated whether and how spatial orientation deficits are modulated by external , contextual changes in
neglect patients . -
pubmed
In a classic rod - and - frame task , we analyzed effects of frame orientation on the subjective visual vertical ( SVV ) in
neglect patients , control
patients with left- or right - sided
brain damage without
neglect and healthy participants . -
pubmed
We found that
neglect patients , but not brain - damaged control patients , generally display a systematic counterclockwise ( CCW ) tilt in their SVV judgments . -
pubmed
METHODS : Retrospective case note analysis of 98
patients who underwent early scanning ( between 7 and 28 days ) of their
fistula as well as routine scanning at 6 weeks over a 2 - year period . -
pubmed
Furthermore , currently adequately powered and optimally designed long - term
prostate disease data are not available to determine if there is an additional risk from normal T values in cured
patients for
PCa . -
pubmed
However , the available data suggest to the expert in sexual medicine that TTh can be cautiously considered in selected hypogonadal
men previously treated for curative intent of low - risk
PCa and without evidence of active disease . -
pubmed
Heterochromatin integrity is crucial for
genome stability and regulation of gene expression , but the factors involved in
mammalian heterochromatin biology are only incompletely understood . -
pubmed
CONCLUSIONS : Intraoperative infusion of
milrinone did not significantly improve the perioperative hemodynamics and the subsequent short term outcomes for the
patients with preexisting
diastolic dysfunction as represented by an elevated E / e ' value , although it reduced the degree of decrease of the SvO(2 ) during OPCAB . -
pubmed
Institutionalized
schizophrenic patients are a high risk group for
hepatitis B virus infection . -
pubmed
In this study ,
cytotoxic effects of
flavones (
apigenin and
luteolin ) on two different
cancer cell lines , including
human chronic myelogenous erythroleukaemia (
K562 ) and
bladder carcinoma (
RT112 ) , were determined , and the molecular mechanisms responsible for their
cytotoxic effects were studied . -
pubmed
Molecular metabolic fingerprinting approach to investigate the effects of
borneol on metabolic alterations in the liver of
nitric oxide deficient
hypertensive rats . -
pubmed
The over all findings demonstrate that in
nitric oxide deficient
animal model of
hypertension , the liver metabolic program is altered through increasing the structural modification in proteins and
triglycerides , and quantitative alteration in proteins , lipids , and glycogen . -
pubmed
Pial arteriovenous fistulae in pediatric
patients : associated
syndromes and treatment outcome . -
pubmed
The presentation , treatment and
syndromes associated with
pAVF in
children are reported here . -
pubmed
Patients with
carotid - cavernous fistulae ,
dural arteriovenous fistulae ,
brain arteriovenous malformations and
vein of Galen malformations were excluded . -
pubmed
RESULTS : Between July 2003 and June 2011 , seven
patients with
pAVF ( six intracranial and one spinal ) were treated . -
pubmed
Functional Status Scale scores at the most recent follow - up were 6 in all but one
patient who had presented with a pretreatment
hemianopsia . -
pubmed
CONCLUSION : Treatment is effective in obliterating
pAVF in
children , with an excellent prognosis seen in our cohort . -
pubmed
No
patients had
hemorrhagic hereditary
telangiectasia . -
pubmed
The treatment for
patients with locally advanced , resectable rectal
cancer has evolved over the years . -
pubmed
Since
FOLFOX (
folinic acid ,
5 - FU , and
oxaliplatin ) is the preferred adjuvant chemotherapy regimen for stage III
colon cancer based on randomized clinical trial results , FOLFOX is also recommended for
rectal cancer patients as an adjuvant therapy approach . -
pubmed
Epidemiological features of 1 281
patients with
head injuries arising from the 2008 Wenchuan earthquake . -
pubmed
According to Glasgow Coma Scale score at admission , 1 029
patients presented with mild
injury , 161 moderate
injury and 91 severe
injury . -
pubmed
Repeated administration of
Ro 19 - 8022 resulted also in an increased sensitivity to convulsant action of
pentylenetetrazol in immature
rats ( higher incidence and severity of
seizures ) . -
pubmed
[ Effects of wenhua juanbi recipe on the gene expression profile of the synovium in collagen - induced
arthritic rats ] . -
pubmed
OBJECTIVE : To study the effects of Wenhua Juanbi recipe ( WJR ) on the gene expression profile of the synovium in collagen - induced
arthritis (
CIA )
rats , and to explore its mechanisms for treating
CIA . -
pubmed
Recent long - term prospective studies have shown that 30 % to 65 % of
patients with
idiopathic RBD will eventually develop a
neurodegenerative disorder with the rate of emergence depending on the length of the follow - up period . -
pubmed
METHODS : A retrospective analysis of 20
patients treated for
PSP in our department in the last two years was performed . -
pubmed
METHODS : In an attempt to examine this hypothesis , we assessed the association of the rs12979860 genotypes with
HTLV-1 PvL levels and clinical status in 112 unrelated Brazilian subjects ( 81 HTLV-1 asymptomatic carriers , 24 individuals with
HAM /
TSP and 7 with
Adult T cell Leukemia /
Lymphoma (
ATLL ) ) . -
pubmed
[
Tamoxifen maintained long - term complete response in an elderly
patient with
breast cancer ] . -
pubmed
At present , 3 months after the operation , our
patient is alive with no
recurrence . -
pubmed
Renoprotective mechanisms of
telmisartan on
renal injury and
inflammation in SHRSP.Z - Leprfa / IzmDmcr
rats . -
pubmed
BACKGROUND : SHRSP.Z - Lepr(fa)/IzmDmcr ( SHRSP fatty )
rats create a new
animal model of
metabolic syndrome . -
pubmed
RESULTS : Vehicle - treated SHRSP fatty
rats developed
proteinuria and
renal dysfunction , which in the
telmisartan group was less than the vehicle and
hydralazine group without changing blood pressure . -
pubmed
Glomerulosclerosis and interstitial
fibrosis were impaired in SHRSP fatty
rats , and the
renal damage in the
telmisartan group was less than the vehicle and
hydralazine groups . -
pubmed
Nail psoriasis masqueraded by
secondary infection with
Rhodotorula mucilaginosa . -
pubmed
In
levodopa - treated
patients with motor fluctuations who were already receiving optimized dopaminergic treatment , the addition of
rasagiline adjunct therapy significantly improved
tremor symptoms . -
pubmed
Tremor symptoms also improved in a subset of
patients with severe
tremor when
rasagiline was added to their existing PD treatment regimen . -
pubmed
These data suggest that
rasagiline used as monotherapy and as adjunctive therapy is effective for reducing
tremor severity in
patients with
PD . -
pubmed
MATERIALS AND METHODS :
Patients were included if pretreatment MR imaging identifying an intramedullary spinal cord
metastasis and an
[ ( 18 ) F ] FDG - PET examination near the time of MR imaging were available . -
pubmed
RESULTS : The final study sample was 10 PET examinations in 10
patients with 13 intramedullary spinal cord
metastases . -
pubmed
In 7 ( 70 % )
patients , retrospective blinded review demonstrated convincing evidence of 10 ( 77 % ) intramedullary spinal cord
metastases . -
pubmed
Intramedullary spinal cord
metastasis was confidently reported clinically in 2 ( 20 % )
patients , accounting for 5 ( 38 % ) intramedullary
spinal cord metastases . -
pubmed
Supplementation with
quercetin attenuates
4 - nitrophenol - induced
testicular toxicity in adult
male mice . -
pubmed
The beneficial effects of
quercetin on
reproductive damage elicited by
4 - nitrophenol (
PNP ) were studied in adult
male mice . -
pubmed
Taken together , these findings indicated that the antioxidant
quercetin displays a potential preventive effect on
PNP - induced oxidative damage in
mouse testes and may represent an efficient supplement to attenuate
reproductive toxicity from environmental toxicants in order to ensure reproductive health and sperm production . -
pubmed
A 24 - year - old
woman with
congenital adrenal hyperplasia (
CAH ) was referred for evaluation of elevated liver enzyme activities over the preceding 6 months . -
pubmed
The
patient was diagnosed with
CAH at the age 12 when she presented with
irregular menses and
hirsutism . -
pubmed
A few studies have shown that
patients with
CAH often develop
metabolic abnormalities and
insulin resistance , particularly women treated with
glucocorticoid for several years . -
pubmed
It is important to be aware that
steatohepatitis can develop in these
patients due to long - term glucocorticoid use and potentially lead to progressive
liver damage . -
pubmed
Furthermore , in
patients with
CAH who develop abnormal liver enzyme activities a liver biopsy is warranted to assess for
steatohepatitis and any associated
fibrosis . -
pubmed
We present a case of
GBS in a thirteen years old
boy who developed severe
tongue weakness and
wasting at two weeks after the onset of
GBS . -
pubmed
Hemodynamic and neuropathological analysis in
rats with
aluminum trichloride - induced
Alzheimer ' s disease . -
pubmed
BACKGROUND AND AIMS : Hemodynamic normality is crucial to maintaining the integrity of cerebral vessels and , therefore , preserving the cognitive functions of
Alzheimer ' s disease patients . -
pubmed
Synchronously , the regional cerebral blood flow ( rCBF ) of the
rats with
AlCl3 - induced
AD were measured using magnetic resonance imaging ( MRI ) . -
pubmed
The results also show that the reduction of rCBF in
rats with
AlCl3 - induced
AD was approximately 50 % to 60 % that of normal
rats . -
pubmed
CONCLUSION : The results accentuate the importance of hemorheology and reinforce the specific association between hemodynamic and neuropathological changes in
rats with
AlCl3 - induced
AD . -
pubmed
METHODS : Right
heart failure was induced by right coronary artery ligation in a
sheep model . -
pubmed
Single
rapamycin administration induces prolonged downward shift in defended
body weight in
rats . -
pubmed
Instead , RAP
animals defended a lower
body weight achieved after
RAP treatment . -
pubmed
METHODS : Forty - seven
AEF patients were included in this study . -
pubmed
OBJECTIVES : To investigate the efficacy of stretch - and - flow voice therapy as a primary physiological treatment for
patients with hyperfunctional
voice disorders . -
pubmed
METHODS :
Participants with a diagnosis of primary
muscle tension dysphonia or
phonotraumatic lesions due to
hyperfunctional vocal behaviors were included . -
pubmed
Circulating miR-126 - 3p levels were determined in 136 healthy
subjects ( CTRs ) aged 20 - 90 years and 193
patients with
type-2 diabetes mellitus (
T2DMs ) aged 40 - 80 years , to explore the combined effect of age and glycemic state on miR-126 - 3p expression . -
pubmed
Aging / senescence - associated miR-126 - 3p up - regulation is likely a senescence - associated compensatory mechanism that is blunted when endothelial cells are exposed to high
glucose levels , a phenomenon that probably occurs in vivo in
T2DM patients . -
pubmed
Spatial patterns of structural brain changes in
type 2 diabetic patients and their longitudinal progression with intensive control of blood
glucose . -
pubmed
RESEARCH DESIGN AND METHODS : Using baseline MRIs of 488
participants with
type 2 diabetes from the Action to Control Cardiovascular Risk in
Diabetes - Memory in
Diabetes ( ACCORD - MIND ) study , we applied a new voxel - based analysis methodology to identify spatially specific patterns of gray matter and white matter volume loss related to
diabetes duration and HbA1c . -
pubmed
RESULTS :
Participants with longer
diabetes duration had significantly lower gray matter volumes , primarily in certain regions in the frontal and temporal lobes . -
pubmed
RESULTS : Out of the 5,352
patients managed during the period , 474 ( 8.9 % ) were blind , 3,178 ( 59.4 % ) had
low vision while 1,700 ( 31.7 % ) had " normal vision " . -
pubmed
In a single ascending dose study conducted in healthy
subjects ,
JNJ-42847922 increased
somnolence and displayed a favorable pharmacokinetic and safety profile for a sedative / hypnotic , thus emerging as a promising candidate for further clinical development for the treatment of
insomnia . -
pubmed
KEY RESULTS : A
resveratrol tetramer ,
vitisin B from
grapevine root extract showed high potency against
HCV replication ( EC50 = 6 nM ) with relatively low
cytotoxicity ( EC50 & gt;10 muM ) . -
pubmed
In this study , 275
patients in use of
tenofovir were retrospectively followed - up for three years to evaluate risk factors involved in
impaired renal function . -
pubmed
Systemic arterial hypertension (
SAH ) and
diabetes were found in 20.4 % and 8.7 % of the
patients , respectively . -
pubmed
TDF was discontinued in 12
patients , one because of a
femoral neck fracture ( 0.7 % ) and 11 due to
nephrotoxicity ( 4 % ) . -
pubmed
Functional Recovery of a
Human Neonatal Heart After Severe
Myocardial Infarction . -
pubmed
Recently , cardiac regeneration has been demonstrated in
fish and newborn
mice after apex resection or
cardiac infarctions . -
pubmed
OBJECTIVE : To assess whether
human neonatal hearts can functionally recover after
myocardial infarction . -
pubmed
METHODS AND RESULTS : Here , we report the case of a newborn
child having a severe
myocardial infarction due to
coronary artery occlusion . -
pubmed
The
child developed massive
cardiac damage as defined by serum markers for cardiomyocyte cell death , electrocardiograms , echocardiography , and cardiac angiography . -
pubmed
CONCLUSIONS : These data indicate that , similar to neonatal
rodents , newborn
humans might have the intrinsic capacity to repair
myocardial damage and completely recover cardiac function . -
pubmed
The evaluation of M - I disposition is important for the pharmacokinetics , pharmacodynamics and
toxicity of
TAK-475 in
animals and
humans . -
pubmed
In this chapter , we describe : ( 1 )
animal models available for assessing the effect of potential medications on specific aspects of
CUD , ( 2 ) the main findings obtained so far with these
animal models , ( 3 ) the approaches used to assess potential medications in
humans in laboratory experiments and clinical trials , and ( 4 ) the effectiveness of several potential pharmacotherapies on particular aspects of
CUD modeled in these
human studies . -
pubmed
In
CPD patients , age ,
MEM effects on PPI , and rs1337697 predicted sensitivity to the neurocognitive effects of
MEM . -
pubmed
CSF samples from
patients with unruptured
aneurysms were used as controls . -
pubmed
Link between nasal carriage of
Staphylococcus aureus and infected
diabetic foot ulcers . -
pubmed
AIMS : Nasal carriage of
Staphylococcus aureus in
diabetic patients may be a risk factor for
diabetic foot lesion infections . -
pubmed
METHODS : A total of 4000
dogs which had been consecutively scored for
canine hip dysplasia were checked for the presence of a
LTV . -
pubmed
RESULTS : In
dogs with an asymmetrical
LTV , the hip joint was significantly more predisposed to
subluxation and malformation on the side of the intermediate or sacral - like transverse process ( p & lt;0.01 ) , on the side of the elevated pelvis ( p & lt;0.01 ) , or when an asymmetrical LTV resulted in pelvic rotation on its long axis ( p & lt;0.01 ) , whereas hip joint conformation was less affected on the side featuring a free transverse process ( p & lt;0.01 ) . -
pubmed
Asymmetrical hip conformation may therefore be the sequela of a
LTV and mask or aggravate genetically induced
canine hip dysplasia . -
pubmed
The impact of
influenza varied by subtype and age group across the five seasons with the highest crude cumulative hospitalisation incidence for
influenza A / H1N1pdm09 cases in 2010/2011 and in 0 - 4 year olds each season for all - subtypes . -
pubmed
Ichthyosis fetalis in a cross - bred
lamb . -
pubmed
Two congenital forms of
ichthyosis are recognized in
animals :
fetalis (
IF ) and congenita . -
pubmed
HYPOTHESIS / OBJECTIVES : To provide clinical , laboratory and pathological assessments of a case of
IF in a cross - bred
lamb . -
pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : This case report describes a case of presumptive
ichthyosis fetalis in a
lamb . -
pubmed
Here , we employed
bisulfite DNA - modification assays to analyze the methylation status of the Igkappa locus in primary pre - B cells from
RAG - deficient mice with pre - rearranged Igh knock - in allele . -
pubmed
INTRODUCTION : The main risk factors for
head and neck squamous cell carcinoma (
HNSCC ) are
tobacco and
alcohol consumption and
human papillomavirus ( HPV ) infection . -
pubmed
Giardiasis is a treatable disease , caused by the flagellated protozoan parasite ,
Giardia duodenalis (
G. - pubmed
Recent gene expression profiling has proven successful in predicting the outcome of
prostate cancer patients ; however , they have yet to provide targeted therapy approaches that could inhibit a
patient 's progression to metastatic
disease . -
pubmed
Treatment options have been increasingly growing in the past years and newer drugs , some with novel mechanisms of action , are being developed for treating
patients with
MS . -
pubmed
To address this question , we measured
human brain activity before and after fear acquisition under conditions of 24 h
sleep deprivation versus normal sleep using resting - state functional magnetic resonance imaging ( rs - fMRI ) . -
pubmed
Fifty eyes of 50
patients in
ARC group and fifty eyes of 50
patients in
myopia with
cataract group were included . -
pubmed
(
Lamiaceae ) is native to Southern California and was reportedly used by the Chumash people as a disinfectant and for the treatment of
rheumatism . -
pubmed
Both proteins are expressed in non -
HGPS individuals , and physiological aging shares many features of
progeria . -
pubmed
BACKGROUND :
Hydroxychloroquine (
HCQ ) is a widely prescribed medication to
patients with
systemic lupus erythematosus (
SLE ) , with potential anti - inflammatory effects . -
pubmed
METHODS : In this prospective cohort study , 41 newly diagnosed
SLE patients receiving 400 mg
HCQ per day were included . -
pubmed
Long - term effects of combined percutaneous
atrial septal defect occlusion and pulmonary valvuloplasty in
children & lt ; 2.5 years old . -
pubmed
Effectiveness and cost - effectiveness of neuromuscular exercise and back care counseling in female healthcare
workers with recurrent non - specific
low back pain : a blinded four - arm randomized controlled trial . -
pubmed
METHODS : We randomly assigned female healthcare
workers with recurrent non - specific
LBP to one of four study - arms : Combined neuromuscular exercise and back care counseling ; Exercise ; Counseling ; and no intervention Control . -
pubmed
RESULTS : From 2014 to 2017 , 108
AHI ( 80 first
infections , 28 reinfections ) were reported in 96 MSM (
HIV - infected 72 ,
HIV - negative 24 ) . -
pubmed
All clusters included
HIV - infected MSM , 6 also included
HIV - negative MSM . -
pubmed
METHODS : We performed a multicenter , randomized trial of
patients with a large nonpedunculated colon
polyp ( & gt;=20 mm ) at 18 medical centers in North America and Spain from April 2013 through October 2017 . -
pubmed
Postprocedure
bleeding occurred in 3.5 % of
patients in the clip group and 7.1 % in the control group ( absolute risk difference [ ARD ] 3.6 % ; 95 % confidence interval [ CI ] 0.7%-6.5 % ) . -
pubmed
The graft and
patient survival and complications were not influenced by the time of transplant for both
HCC and non -
HCC population . -
pubmed
Sacubitril / valsartan for
heart failure in
adults with complex
congenital heart disease . -
pubmed
BACKGROUND :
Heart failure is an important cause of morbidity and mortality in
adults with
congenital heart disease (
ACHD ) . -
pubmed
METHODS : Retrospective study of
ACHD patients with
CHD of moderate / severe complexity and
heart failure under treatment with
sacubitril / valsartan . -
pubmed
CONCLUSION : In this small group of complex
ACHD patients with
heart failure , treatment with
sacubitril /
valsartan did not improve systemic ventricular function or functional status . -
pubmed
Their critical function in heart formation is evidenced by the phenotypes of
animal models lacking these factors and by the broad spectrum of
human congenital heart diseases associated with mutations in their genes . -
pubmed
This in turn will greatly improve diagnosis and care for the millions of
individuals affected by congenital and acquired
cardiac disease worldwide . -
pubmed
A 65 - year - old
man underwent high tibial osteotomy after the diagnosis of the right
knee osteoarthritis . -
pubmed
Markers flanking each QTL were physically mapped against the
durum wheat reference sequence and candidate genes involved in
disease resistance were identified within the QTL intervals . -
pubmed
Transcatheter aortic valve replacement : A potential option for
aortic insufficiency management in
patients with left ventricular assist device . -
pubmed
PATIENT CONCERNS : A 46 - year - old
woman with 3 previous vaginal deliveries underwent laparoscopic mesh sacrohysteropexy for stage III
uterine prolapse . -
pubmed
One month after surgery , the
patient developed persistent symptoms , such as stiffness of the lumbosacral portion ,
low back pain (
LBP ) , persistent
swelling ,
pain between the right iliac crest and the buttock ,
inability to bend down , and
pain in the right lower limb . -
pubmed
Lipid abnormalities , including
hypertriglyceridemia , are one of the most common comorbidities in
patients with
chronic kidney disease (
CKD ) and are independently associated with
disease progression . -
pubmed
A recent clinical study demonstrated that
pemafibrate was safe and effective for correcting pro - atherogenic lipid abnormalities in
CKD patients with a wide range of
renal insufficiency . -
pubmed
However , the effect of
pemafibrate on renal function in
patients with
IgAN and
hypertriglyceridemia has not been verified . -
pubmed
These findings suggest that
pemafibrate is safe and effective for correcting
hypertriglyceridemia and decreasing urinary protein excretion without changing
eGFR and blood pressure levels in mild
IgAN patients with
hypertriglyceridemia . -
pubmed
BACKGROUND :
Pain is a common symptom for
patients with
pancreatic cancer and is often treated using palliative radiation therapy . -
pubmed
With the recent advancements in radiation dosimetric planning and delivery , the Juravinski Cancer Centre in Hamilton , Ontario , offers a hypofractionated dose of 2500 cGy in 5 fx for the improvement of
pain and
tumour control in selected
pancreatic cancer patients . -
pubmed
METHODS : A retrospective analysis of 24
patients diagnosed with unresectable
pancreatic cancer was conducted . -
pubmed
CONCLUSION : A palliative radiotherapy dose regime of 2500 cGy/5 fx demonstrates a potential for the effective control of
pain with limited acute
toxicities in
patients with unresectable
pancreatic cancer . -
pubmed
In this study , we tested its antiviral activity of
DENV ,
JEV and
ZIKV , and found that POM-12 dramatically inhibited their
infection with IC50 value of 1.16 muM , 1.9 muM and 0.64 muM , respectively . -
pubmed
METHODS : In this prospective , monocentric , case series study , consecutive
patients who fulfilled the following inclusion criteria benefited from an early postmortem structural brain MRI : death < 24 hours , SARS - CoV-2 detection on nasopharyngeal swab specimen , chest computerized tomographic ( CT ) scan suggestive of
COVID-19 , absence of known focal
brain lesion , and MRI compatibility . -
pubmed
SARS - CoV-2 - related
olfactory impairment seems to be limited to olfactory bulbs . -
pubmed
We sought to describe the frequency of achievement of therapeutic
vancomycin concentrations in
critically ill patients receiving ECMO with therapeutic drug monitoring ( TDM ) . -
pubmed
In this retrospective observational study , we included all
critically ill patients receiving
TDM for
vancomycin whilst on ECMO . -
pubmed
Patients not receiving RRT and those with mild to moderate
acute kidney injury (
AKI ) were at a risk of underdosing while those with established
AKI on RRT may experience supratherapeutic concentrations . -
pubmed
Moreover ,
PDMS - SB - UU showed a lack of
hemolysis and
cytotoxicity with whole
ovine blood and
rat vascular smooth muscle cells ( rSMCs ) , respectively . -
pubmed
GM2
ganglioside accumulation causes neuroinflammation and behavioral alterations in a
mouse model of early onset
Tay - Sachs disease . -
pubmed
Although
Tay - Sachs patients appear normal at birth , the progressive accumulation of undegraded
GM2 gangliosides in neurons leads to
death . -
pubmed
Progressive accumulation of GM2 led to premature
death of the double KO
mice . -
pubmed
Importantly , this double - deficient
mouse model displays typical features of
Tay - Sachs patients , such as cytoplasmic vacuolization of nerve cells ,
deterioration of Purkinje cells ,
neuronal death ,
deceleration in movement ,
ataxia , and
tremors . -
pubmed
Furthermore , our work contributes to better understanding of the neuropathology in a
mouse model of early onset
Tay - Sachs disease . -
pubmed
Deep sequencing detects
human papillomavirus (
HPV ) in
cervical cancers negative for
HPV by PCR . -
pubmed
BACKGROUND :
Human papillomavirus (
HPV ) is a necessary cause of
cervical cancer , although some invasive
cervical cancers may test negative by
HPV PCR . -
pubmed
CONCLUSIONS : Unbiased deep sequencing provides comprehensive data on
HPV types in
cervical cancers and appears to be an important tool for quality assurance of
HPV screening . -
pubmed
Some of the mechanisms of
fibrosis development have been described using
rodent models ; however , the relevance of findings in these
animal models is difficult to assess . -
pubmed
METHODS : To overcome this unmet need of investigating
IPF with a relevant model , we utilized
tree shrews , which are genetically , anatomically , and metabolically similar to
primates and
humans . -
pubmed
Using
human antibodies and primers , we investigated the role of macrophage phenotypic switching in normal and
IPF subjects and
bleomycin - injured tree shrews . -
pubmed
CONCLUSION : The profibrotic polarization of macrophages has been demonstrated to be present in
IPF subjects and in fibrotic
mice . -
pubmed
These observations demonstrate that
tree shrews are an ideal
animal model to investigate the pathogenesis of
IPF as they are genetically , anatomically , and metabolically closer to
humans than the more commonly used
rodent models . -
pubmed
Weak anti -
SARS - CoV-2 antibody response is associated with mortality in a Swedish cohort of
COVID-19 patients in critical care . -
pubmed
Quercetin attenuates
naso - sinusal inflammation and inflammatory response in lungs and brain on an experimental model of acute
rhinosinusitis in
rats . -
pubmed
This study aimed to investigate the effect of
quercetin without intranasal
inflammation and oxidative stress in nasal and
sinus mucosa , but also in serum , lungs and brain in a
rat model of
acute nasal and sinus inflammation induced by administration of lipopolysaccharides ( LPS ) ( from
Escherichia coli ) . -
pubmed
The intranasal LPS administration successfully induced acute
rhinosinusitis in a
rat model and also generated an inflammatory response in the lungs and brain . -
pubmed
Initial response of ovarian tissue transcriptome to vitrification or microwave - assisted
dehydration in the domestic
cat model . -
pubmed
Using the prepubertal domestic
cat as a model , the objective was to study immediate effects of vitrification or microwave - assisted
dehydration on the global transcriptome dynamics in the ovarian cortex . -
pubmed
CONCLUSIONS : Our results showed , for the first time , different effects of vitrification and microwave - assisted
dehydration protocols on the global transcriptome of the ovarian cortex ( using the domestic
cat as a biomedical model ) . -
pubmed
Currently recognized sampling practices for general
toxicity studies in
animals , which are based on easily discerned external neuroanatomic landmarks and guided by extant stereotaxic brain atlases , typically will permit histopathologic evaluation of many brain centers involved in visual sensation ( eg , optic chiasm , optic tract , dorsal lateral geniculate nucleus , primary and secondary visual cortices ) and often some subcortical brain nuclei involved in light - modulated nonvisual activities needed for visual attention and orientation ( eg , rostral colliculus in quadrupeds , termed the superior colliculus in bipeds ; several cranial nerve nuclei ) . -
pubmed
Use of immune repertoire sequencing to resolve discordant microscopic and immunochemical findings in a case of
T cell - rich large B cell lymphoma in a young
dog . -
pubmed
BACKGROUND :
Lymphocytic neoplasms with frequent reactive lymphocytes are uncommonly reported in
dogs , and can pose a diagnostic challenge . -
pubmed
CONCLUSIONS :
T cell - rich large B cell lymphoma is a rare
neoplasm in
dogs that may be challenging to diagnose and classify due to mixed lymphocyte populations . -
pubmed
Two long - term therapy trials with high concentrations of antibiotic were carried out to determine the duration of therapy required to achieve bacteriologic cure of experimental
Pseudomonas keratitis in
guinea pigs . -
pubmed
In order to determine the features of early radiologic diagnosis we report the findings of 7 further
patients with neonatal
septic osteoarthritis with clinical and radiological follow - up . -
pubmed
An own case is shown up : There was taken nephrectomy and following local radiation of
hypernephroma in a 59 years old male
patient in spite of pulmonary
metastases . -
pubmed
Sensitivity patterns for the induction of homeotic shifts in a favorable
strain of
mice . -
pubmed
Approaching the clinical problems of
patients with
cerebrovascular disease . -
pubmed
Three antimicrobial combinations ,
ticarcillin plus
cephalothin (
T + C ) ,
ticarcillin plus
gentamicin (
T + G ) , and
cephalothin plus
gentamicin (
C + G ) , were administered to 105 febrile
granulocytopenic cancer patients at the Baltimore Cancer Research Center as part of a multi - institutional prospective randomized antibiotic trial . -
pubmed
The bactericidal activity of the serum from these 32
patients supplements the overall clinical results of the multi - institutional antibiotic trial and suggests that T+G is a useful initial regimen for empiric therapy of febrile episodes in granulocytopenic
cancer patients . -
pubmed
[ Biological characteristics of
influenza B viruses isolated during
influenza B epidemics in 1976 - 1977 ] . -
pubmed
Antisera to new
B / 76 strains neutralized the hemagglutinating activity of all known reference
influenza B virus strains beginning from 1972 . -
pubmed
Unlike the
Yamagata / 1 / 73 strain , all the
influenza B / 76 viruses under study were resistant to thermostable inhibitors of normal
horse ,
guinea pig , and
rabbit sera . -
pubmed
This response occurred both when body
weight gain was used as a measure of intake for
pigs nursing on the sow and when intake was measured directly in bottle - fed
pigs . -
pubmed
Forty consecutive
patients underwent flexible fiberoptic transbronchial lung biopsy for diagnosis of diffuse nodular or
infiltrative lung disease . -
pubmed
In an elderly
man bilateral temporal scalp
necrosis complicating
temporal ( systemic giant cell ) arteritis developed . -
pubmed
The
patient also demonstrated other features characteristic of this entity : ( 1 ) exquisite scalp
tenderness and
headache , ( 2 ) onset late in life , ( 3 )
visual disturbances , ( 4 ) general
debility , ( 5 ) diagnostic temporal artery biopsy , and ( 6 ) gradual healing with
glucocorticosteroid therapy . -
pubmed
The
mouse rendered eosinophilic by
infection with
trichinosis provides a suitable model for study of the eosinopenic response induced by
acute inflammation . -
pubmed
The alterations in eosinophil dynamics associated with acute inflammatory reactions in trichinous
mice were studied with
pneumococcal abscesses , with
Escherichia coli pyelonephritis , with
Coxsackie viral pancreatitis , and with
acute subcutaneous inflammation due to
turpentine . -
pubmed
In absence of specific complex therapy , as it was in our experiments , the
animals die of
shock within the period from 17 min to 5 hour 20 min . -
pubmed
[ Effect of
coccidial infection on
acetylcholine - induced contraction of the digestive tract in
chickens . -
pubmed
Comparison of
infection between
Eimeria maxima and
E. - pubmed
Excitatory
amino acid antagonists and their potential for the treatment of
ischaemic brain damage in
man . -
pubmed
A wide range of therapeutic strategies has been explored in
humans and experimental animals with the aim of improving outcome after
brain ischaemia but few have shown convincing clinical benefit . -
pubmed
This young
man was admitted in our hospital because of
abdominal pain and
hyperamylasemia . -
pubmed
The purpose of this retrospective study is to identify
prostate cancer patients who would benefit from pelvic nodes irradiation ( whole pelvis ) as opposed to the small - field irradiation to the prostate only . -
pubmed
Thus , whole pelvis with prostate boost radiation should be utilized in Stage B and Stage C
cancers as this has shown to increase the survival of the
patient without increasing chronic radiation morbidity . -
pubmed
Auditory evoked response ( AER ) was recorded before , during and after physiotherapy in 11 paralysed (
atracurium 0.56 ( SD ) 0.13 mg kg-1 h-1 ) , sedated (
propofol 2.2 ( 1.0 ) mg kg-1 h-1 ;
fentanyl 4.4 ( 2.3 ) micrograms kg-1 h-1 ) and
critically ill patients undergoing ventilation in the intensive care unit ( ICU ) . -
pubmed
A case of spontaneous
trisomy in the spermatocytes of
Microtus arvalis . -
pubmed
These data suggest that chromosome non - disjunction in premeiotic germ cells can be considered one of the causes of
aneuploidy in
mammals . -
pubmed
Effect of
bis ( bilato )- 1,2 - cyclohexanediammineplatinum ( II ) complexes on lung
metastasis of
B16 - F10 melanoma cells in
mice . -
pubmed
New
platinum ( II ) complexes ,
bis ( bilato )- 1,2 - cyclohexanediammineplatinum ( II ) which were lipophilic and water - miscible , were tested for antitumor activity against lung nodules from intravenously injected
B16 - F10 melanoma cells in
C57BL / 6 mice by intravenous administration of the complexes in water suspension form . -
pubmed
The authors analyzed a group of 64
children with
acute lymphoblastic leukaemia (
ALL ) treated according to three protocols of different intensity . -
pubmed
Successful remission in the entire group of
patients was 93 % , one third of the
children developed during the investigation period a
relapse of the basic disease . -
pubmed
A quantitative analysis of axon outgrowth ,
axon loss , and myelination in the
rat pyramidal tract . -
pubmed
Balloon pulmonary valvuloplasty has been used successfully over the last few years for the relief of moderate to severe valvar
pulmonic stenosis in neonates , infants ,
children , and adults . -
pubmed
Campylobacter jejuni is a common cause of acute
infectious diarrhoea . -
pubmed
Determinants of prognosis in
ventricular tachyarrhythmia patients without induced sustained
arrhythmias . -
pubmed
We studied 59
patients with sustained
ventricular tachycardia (
VT ) or
ventricular fibrillation in whom programmed stimulation induced 15 or fewer repetitive ventricular complexes . -
pubmed
During follow - up of 2.2 + /- 1.5 years , 13
patients had an
arrhythmia recurrence and seven died suddenly . -
pubmed
Prior
myocardial infarction (
MI ) was the only independent predictor of
arrhythmia recurrence ( p less than 0.02 ) and
sudden death ( p = 0.05 ): at 2 years , 36 + /- 12 % of 18
patients with
MI and 8 + /- 4 % of 41
patients without
MI had
arrhythmia recurrence , and 24 + /- 12 % with
MI and 3 + /- 3 % without
MI died suddenly . -
pubmed
None of the nine
patients with greater than or equal to 70 %
coronary stenosis but no
MI had
arrhythmia recurrence after anti - ischemic therapy . -
pubmed
Possible
arrhythmia - precipitating conditions were present during all
arrhythmias in 14
patients , but did not predict freedom from
arrhythmia recurrence ( p = 0.52 ) or
sudden death ( p = 0.81 ) . -
pubmed
The maximum number of induced ventricular complexes did not predict
arrhythmia recurrence or
sudden death : for
patients with 0 to 2 , 3 to 5 , and 6 to 15 induced complexes , the 2 - year incidence of
arrhythmia recurrence was 16 + /- 7 % , 15 + /- 10 % , and 18 + /- 10 % ; for
sudden death , it was 9 + /- 6 % , 0 + /- 0 % , and 14 + /- 9 % . -
pubmed
To determine the sensitivity of arm exercise in detecting
coronary artery disease (
CAD ) , 30
patients with
angina pectoris performed both arm ergometry and treadmill testing before coronary angiography . -
pubmed
Ischemic ST
depression ( greater than or equal to 1 mm ) or
angina occurred more frequently ( 86 % , 26
patients ) with leg exercise than with arm exercise ( 40 % , 12
patients ) . -
pubmed
[ Characteristics of
strains of
Yersinia pestis isolated in the northeastern part of Brazil ] . -
pubmed
Non - specific induction of
cytotoxicity in normal
human lymphocytes in vitro : studies of mechanism and specificity of the reaction . -
pubmed
We have demonstrated autoantibodies to the basement membrane and interstitial collagens in the sera of
patients with
scleroderma (
systemic sclerosis ) ; ELISA ratios correlate directly with the extent of
pulmonary fibrosis in these
patients . -
pubmed
Postictal
seizure inhibition in amygdaloid - kindled
cats . -
pubmed
The results obtained may be summarized as follows : ( 1 ) kindled generalized
convulsions resulted in three consecutive postictal stages before recovery from postictal behavioral
depression ; ( 2 ) in bilaterally kindled
cats , PSI lasted for 3 - 4 h , which was longer than the postictal behavioral
depression ; ( 3 ) no correlation was found between interictal spike frequency and decreased susceptibility to
convulsion during PSI ; ( 4 ) the duration of PSI was prolonged significantly after secondary site amygdaloid kindling ; and ( 5 ) such changes were observed greater than 2 weeks after the last secondary site stimulation . -
pubmed
The
rats fed
vitamin C showed no change of
body weight whilst the
animals fed lard gained in
body weight . -
pubmed
These have been hospital - based and , as such , inevitably over - represent
patients with
chronic epilepsy . -
pubmed
Investigations ( both hospital and community based ) of
patients from the onset of
seizures show a much better prognosis , and most patients suffer only a small number of
seizures in total over a relatively short period of time and then remit . -
pubmed
The traditional view of
epilepsy as a chronic condition with a continuing tendency to relapse is therefore not tenable for the majority of
patients . -
pubmed
The patterns of
epilepsy are established relatively early in its course in most cases , and long term prognosis might therefore be predictable within a few years of the onset of
seizures in most
patients . -
pubmed
Arginine vasotocin and
aggression in
rats . -
pubmed
Between 1968 and 1981 52
patients with
syringomyelia were investigated clinically and with several additional procedures . -
pubmed
From own experiences the following measurements are indicated in
patients with presumed
syringomyelia :
X - rays of the cervical and thoracal spinal column and the skull have to be complemented by automatic computerized transverse axial tomography ( ACTA ) of the spinal canal . -
pubmed
Genetic control of resistance to
Salmonella typhimurium infection in high and low antibody responder
mice . -
pubmed
Mice selected by Biozzi for high and low responses to
sheep erythrocytes were investigated for resistance to subcutaneous
Salmonella typhimurium infection . -
pubmed
Analysis of resistance data of backcrosses of ( high x low)F1 with either parental
strain showed this genetic control to be at least one other gene in the Biozzi
mice , not linked to Ity . -
pubmed
To validate the use of
99mTc - PIPIDA in the diagnosis of
biliary tract disease , 117
patients with clinical symptoms of
acute cholecystitis were prospectively scanned as an initial screening test . -
pubmed
Complete
common duct obstruction was confirmed at surgery in 12
patients ( 100 % ) . -
pubmed
In Experiment 1 ,
rats suppressed responding to a compound light + tone stimulus that was repeatedly paired with
shock . -
pubmed
Groups of
rats were then presented with only one element of the compound ( the tone ) , either presented alone or paired with
shock , for 15 days . -
pubmed
Rats that had received the tone paired with
shock during the intervening training continued to suppress to the light , whereas
rats that had received the tone alone showed rapid extinction of the CER to light . -
pubmed
Sulindac (
Clinoril ) was tested in an open clinical - therapeutical study with regard to its analgesic effect and the improvement of function in 20
patients of both sexes suffering from
periarthropathy of the hip or shoulder . -
pubmed
The therapeutic effect was judged on the basis of the influence on the spontaneous
pain and on the
pain by pressure , on the functional improvement and on the daily habits of the
patients . -
pubmed
Eighteen
mongrel dogs were divided into two groups :
hypoxic control group ( FIO2 = 11 % , n = 10 ) and
NO inhalation group ( FIO2 = 11 % ,
NO inspiratory concentration = 44 ppm , n = 8) . -
pubmed
In all three
patients , effusion cytology revealed
Burkitt ' s lymphoma , characterized by a uniform population of non - cohesive lymphoid cells with noncleaved nuclei , prominent multiple nucleoli , and scanty - to - moderate basophilic cytoplasm . -
pubmed
In vivo selection of long terminal repeat alterations in
feline leukemia virus - induced
thymic lymphomas . -
pubmed
To determine what genetic changes are selected in the enhancer sequences of the
feline leukemia virus (
FeLV ) long terminal repeat in
cats that develop
T cell tumors , we cloned proviral U3 sequences in
cats that died with
thymic lymphoma following infection with molecularly cloned
FeLV . -
pubmed
Additionally , in clones from two of four
cat tumors , portions of the enhancer including Lvb and core were duplicated with respect to the single enhancer unit of the inoculating virus . -
pubmed
In contrast , a PCR survey of necropsy DNA samples derived from five
cats that did not develop
tumors revealed that all retained the single enhancer unit of the infecting virus . -
pubmed
These results demonstrate that viruses with duplicated enhancers can be generated and selected after only a single passage in
cats , and furthermore , that such viruses may be particularly selected in
tumors . -
pubmed
CAST
patients receiving beta - blocker therapy had significantly enhanced survival at 30 days , and at 1 and 2 years of follow - up against all - cause and
arrhythmic death or nonfatal
cardiac arrest . -
pubmed
In CAST
patients with a history of
congestive heart failure , beta - blocker therapy was independently associated with longer time to occurrence of new or worsened
congestive heart failure ( p = 0.015 ) . -
pubmed
Antitumor activity and tissue distribution of
bis ( bilato )- 1,2 - cyclohexanediammineplatinum ( II ) complexes in
BDF1 mice with
murine reticulum cell sarcoma (
M5076 ) . -
pubmed
Murine reticulum cell
sarcoma (
M5076 ) was subcutaneously implanted into
BDF1 mice and then the antitumor activity of seven micelle - forming type
platinum complexes was tested . -
pubmed
The total
Pt levels were significantly higher in
tumor tissue from
mice given the more active complex than in
tumor tissue from
mice given the less active complex . -
pubmed
The
patient presented with sudden onset of left arm
pain ,
shortness of breath ,
nausea ,
vomiting , and
diaphoresis . -
pubmed
Misdiagnosis is common , as it is seen in the same
patients at risk for
ischemic heart disease ,
stroke , and other
vascular abnormalities . -
pubmed
Impairment of intracortical GABAergic inhibition in a
rat model of
absence epilepsy . -
pubmed
The WAG / Rij
rat strain is characterized in its EEG by the manifestation of spike - wave discharges which resemble in their spontaneous appearance and pharmacological sensitivity the
absence epilepsy observed in
humans . -
pubmed
In order to test the hypothesis whether cellular intrinsic membrane and/or synaptic network properties in the neocortex are modified in this form of
epilepsy , we analyzed with extra- and intracellular recording techniques the functional status of neocortical slices obtained from adult
epileptic WAG / Rij
rats and compared them with the data acquired from non -
epileptic control
Wistar rats . -
pubmed
Our data indicate that the imbalance between intracortical excitatory and inhibitory mechanisms may at least contribute to the expression and augmentation of spike - wave discharges in
epileptic WAG / Rij
rats . -
pubmed
Sympathetic skin response in
parkinsonian patients . -
pubmed
Sympathetic skin response ( SSR ) was recorded in 23
patients with
idiopathic Parkinson ' s disease (
IPD ) using mechanical as well as electrical stimuli . -
pubmed
Central mechanisms might be responsible for these findings and the role of central sympathetic pathway damage in
parkinsonian patients is discussed . -
pubmed
Physical responses to different modes of interval exercise in
patients with chronic
heart failure -- application to exercise training . -
pubmed
METHOD : In exercise training with chronic
heart failure patients , working muscles should be stressed with high intensity stimuli without causing cardiac overstraining . -
pubmed
In this study , three interval exercise modes with different ratios of work/ recovery phases ( 30/60 s , 15/60 s and 10/60 s ) and different work rates were compared during cycle ergometer exercise in
heart failure patients . -
pubmed
It showed high in vitro activity , comparable to those of
meropenem and a new
carbapenem ,
BO-2727 , against
methicillin - susceptible
Staphylococcus aureus and
streptococci , with MICs at which 90 % of
strains tested are inhibited ( MIC90S ) of & lt ; or = 0.39 microgram / ml . -
pubmed
Against members of the family Enterobacteriaceae ,
Moraxella catarrhalis , and
Haemophilus influenzae ,
ER-35786 inhibited 90 % of
strains tested at a concentration of & lt ; or = 1.56 micrograms / ml . -
pubmed
The in vivo activity of
ER-35786 was highest for systemic
infection models with
methicillin - resistant
S. - pubmed
In acute
pneumonia caused by
P. - pubmed
Peculiarities of formation of connective tissue framework of granulation tissue and
scar were studied using light optical and scanning electron microscopy in
rats during all - layer skin
wound healing in interscapular region . -
pubmed
The response to progressive increases in heart rate to 150 to 160 beats / min by right atrial pacing before and during
dobutamine infusion was studied in 3 relatively normal
subjects and in 5
patients with severe
dilated cardiomyopathy . -
pubmed
In
patients with
heart failure , the heart rate versus LV dP / dt(max ) relations were
depressed and flattened without a descending limb . -
pubmed
In
patients with
heart failure , a depressed and flattened relation between heart rate and LV dP / dt(max ) ( force - frequency effect ) did not show the amplification of myocardial contractility by beta - adrenergic stimulation observed in the normal heart . -
pubmed
An on - farm study of the epidemiology of
Actinobacillus pleuropneumoniae infection in
pigs as part of a vaccine efficacy trial . -
pubmed
Thirty cohort
pigs were followed from birth to slaughter to study epidemiological patterns of porcine
pleuropneumonia caused by
Actinobacillus pleuropneumoniae . -
pubmed
This study is based on 80
children with
forearm fractures treated with intramedullary nailing : 64
boys and 16
girls , aged 6 to 16 ( 23 right sides , 58 left sides : 81
fractures ) . -
pubmed
Ten
children experienced complications , but only complications involving the skin and
sepsis were due to the technique . -
pubmed
Effect of jiawei shenqi dihuang tang on the content of urinary protein in
patients with
diabetic nephropathy . -
pubmed
The treatment of
schizophrenic patients who fail adequate trials of typical neuroleptics is a major challenge . -
pubmed
This article provides information on the efficacy of
olanzapine for various symptoms of
schizophrenic patients and drug safety . -
pubmed
Olanzapine is significantly superior to
haloperidol in positive , negative , and
depressive symptoms of
patients , and for
tardive dyskinesia and
extrapyramidal symptoms . -
pubmed
In 3
patients ,
ischemic lesions demonstrated by the SPECT study was not shown in the MRI study because of motion artifacts . -
pubmed
In conclusion , FAIR imagings are considered to be useful in the evaluation of cerebral flow dynamics in the
ischemic stroke patients . -
pubmed
Our studies demonstrate that the kinetics of cytokine gene expression can reveal additional dysregulation of the immune system in
HIV infection , suggesting that PBMC of
HIV - infected persons exist in an activated state in vivo that permits them to express cytokine genes more rapidly than a normal PBMC . -
pubmed
METHODS : Between 1988 and 1996 , 58
patients were treated with
spondylitis or
spondylodiscitis . -
pubmed
CONCLUSIONS : We recommend surgical treatment on
patients with major vertebral body destruction ,
epidural abscess and progressive
neurological impairment . -
pubmed
A rod - shaped heliobacterium motile by peritrichous flagella , designated
strain OS - H1 , was isolated from a sample of shoreline soil of the soda lake Ostozhe ( pH 9.2 , total salt content 0.22 % ) located in the steppe of south - east Siberia . -
pubmed
The G+C content of
strain OS - H1 was 45.0 mol% . -
pubmed
There is growing concern that the metabolic complications associated with
HIV and antiretroviral therapy may lead to accelerated
coronary artery disease (
CAD ) . -
pubmed
We report a
patient with severe
varus deformity and
tibial shortening caused by
dysplasia epiphysealis hemimelica (
DEH ) , a rare
skeletal developmental disorder characterized by an
osteocartilaginous tumor arising from an epiphysis in young
children . -
pubmed
We report an uncommon case of unilateral spontaneous
hematoma of the right adrenal gland in a 22 - year old young
man . -
pubmed
Generalized
convulsive seizures are often well controlled through classic antiepileptic drugs ( AEDs ) like
valproate and
clonazepam , whereas
myoclonus , the main symptom that is affecting
patients most in their daily life , is usually refractory to standard AEDs . -
pubmed
A definitive diagnosis could not be made for 5
patients because of lack of histological evidence , but clinical and biological arguments suggested diagnosis of
WG . -
pubmed
Recently , we have followed up patients with
infections caused by
MRSA ,
Pseudomonas aeruginosa and
Serratia or carriers of these bacteria , and determined the drug sensitivities of clinical isolates . -
pubmed
Platinum - based chemotherapy is the cornerstone of care for
patients with metastatic
non - small - cell lung cancer (
NSCLC ) . -
pubmed
Preclinical and
human studies suggest that the orbital frontal cortex and anterior cingulate cortex play an inhibitory role in the regulation of
aggression . -
pubmed
METHODS : Using positron emission tomography , regional metabolic activity in response to a serotonergic stimulus ,
meta - chlorophenylpiperazine (
m - CPP ) , was examined in 13
subjects with
impulsive aggression and 13 normal controls . -
pubmed
CONCLUSIONS : The decreased activation of inhibitory regions in
patients with
impulsive aggression in response to a serotonergic stimulus may contribute to their difficulty in modulating aggressive impulses . -
pubmed
Furthermore , PC(20)FEV(1 ) values in non - asthmatic
children with
allergic rhinitis ( n = 24 ) were not significantly different from those seen in asymptomatic atopic ( n = 54 ) or non - atopic controls ( n = 92 ) . -
pubmed
Therefore , secondary preventive measures in non - asthmatic
children with
allergic rhinitis ( such as regular local anti - inflammatory therapy or specific immunotherapy ) should be studied and applied more intensely to prevent bronchial hyper - responsiveness ( BHR ) and
asthma in this high - risk group . -
pubmed
The guidance outlines experimental approaches to evaluating the carcinogenic potential of pharmaceuticals to
humans that may obviate the necessity for the routine conduct of two long - term rodent
carcinogenicity studies -
pubmed
We studied the effects of photosensitizing
hypericin in both primary cell cultures and cell lines ( squamous :
Kyse-140 and
adenocarcinoma :
OE-33 ) of
human esophageal cancer using an incoherent white light source . -
pubmed
High - dose therapy and autologous stem - cell transplantation versus conventional therapy for
patients with advanced
Hodgkin ' s lymphoma responding to front - line therapy . -
pubmed
PURPOSE : To determine whether high - dose therapy ( HDT ) with autologous stem - cell transplantation ( ASCT ) should be included in the initial consolidative treatment of
patients with advanced , unfavorable
Hodgkin ' s lymphoma (
HL ) . -
pubmed
MATERIAL AND METHODS : The analysis of clinical characteristics and course of
APSN has covered 24
patients with
PAPS ( 16
females and 8
males , mean age 34.3 years ) . -
pubmed
RESULTS :
PAPS patients developed renal affection in the onset of
APS or within the first 5 years of its course . -
pubmed
In the majority of
patients APSN combined with abnormalities of CNS , heart and skin . -
pubmed
[
Motion sickness in
animals ] . -
pubmed
We investigated in
children with
attention - deficit - hyperactivity disorder (
ADHD ) the ability to programme and execute goal - directed arm movements . -
pubmed
In this condition , the
children with
ADHD exhibited large end - point errors and prolonged movement durations . -
pubmed
Such hyperlactatemic
acidosis is particularly marked in
lactate - intolerant patients (
shock with
lactic acidosis and/or
liver disease ) and is particularly strong if high - volume hemofiltration is performed with the associated high
lactate load , which overcomes the
patient 's metabolic capacity for
lactate . -
pubmed
METHOD : The Irish
Risperidone Olanzapine Drug Outcomes studies in
Schizophrenia ( RODOS ) programme was a retrospective review of medical notes and prescription charts in 396
inpatients with
schizophrenia or
schizoaffective disorder . -
pubmed
To address this question , we examined the genetic basis of
bony armor loss in three freshwater populations of
Alaskan threespine stickleback ,
Gasterosteus aculeatus , that evolved from fully armored anadromous populations in the last 14,000 years . -
pubmed
METHODS : A total of 10
women with
adenomyosis ( study group ) and 12
women with
uterine myoma ( control group ) were included in this study . -
pubmed
Extended phenotypic and genotypic characterization of a limited number ( n=31 ) of isolates from 2002 showed that
fusidic acid - resistant
strains of
S. - pubmed
METHODS : Forty - eight
rats were divided randomly into 4 groups : the normal control group , Yin -
jaundice model group , Yang -
jaundice model group , Yinchen Shufu Decoction treatment group . -
pubmed
[ Motor skills and
psychiatric disturbances in
children ] . -
pubmed
RESULTS : More than 40 % of the
children examined showed
motor deficiency . -
pubmed
Psychobehavioral and nutritional predictors of
weight loss in
obese women treated with
sibutramine . -
pubmed
OBJECTIVE : To reveal whether baseline
body mass index (
BMI ) , and psychobehavioral and nutritional markers were significant predictors of the change in
BMI observed after 4 and 12 months in
obese women enrolled in a
weight reduction program , including low - energy diet , increased physical activity , cognitive behavior therapy and
sibutramine . -
pubmed
SUBJECTS : In total , 80
obese women ( age : 43.9+/-10.6 y , BMI : 36.7+/-4.8 kg / m(2 ) ) . -
pubmed
Variation in recombination rate may bias
human genetic
disease mapping studies . -
pubmed
Previously we have found a functional synergistic interaction after co - administration of
gabapentin and
B vitamins by using a
neuropathic pain model in the
rat . -
pubmed
In order to evaluate the efficacy of
gabapentin and
B vitamins in the treatment of
diabetic neuropathy in
humans we carried out a comparative trial . -
pubmed
Both treatments significantly reduced
pain and improved quality of life in the
patients . -
pubmed
Data suggest that the combination of
gabapentin and
B vitamins could be an alternative treatment for
diabetic neuropathic patients . -
pubmed
Spectroscopic evidence of
cerebral axonopathy in
patients with " pure "
adrenomyeloneuropathy . -
pubmed
OBJECTIVE : To investigate brain involvement in
AMN patients with normal MRI , employing multislice MR spectroscopic imaging . -
pubmed
METHODS : Twelve
men with pure
AMN were compared with 19 age - matched healthy
volunteers . -
pubmed
CONCLUSIONS :
( 1 ) H - MR spectroscopic imaging is able to detect biochemical abnormalities suggestive of
axonal damage even in the brains of
patients with pure
adrenomyeloneuropathy . -
pubmed
METHODS : We studied the association between endogenous sex hormones and characteristics of the
metabolic syndrome in 400 independently living
men between 40 and 80 yr of age in a cross - sectional study . -
pubmed
OBJECTIVE : The main objective of the trial was to evaluate the efficacy and tolerance of a three - month pulsed
estrogen therapy with intranasal
17 beta - estradiol in
patients with
menopausal symptoms . -
pubmed
The
night sweats were observed before the treatment in 90.5 %
patients with frequency of 8.8 per week . -
pubmed
After 3 and 4 months of treatment the proportion of
patients with
night sweats decreased to 28.2 % and 11.8 % respectively , and the number of episodes to 2.7 and 2.2 per week ( p & lt ; 0.0005 ) . -
pubmed
Osteoporosis can also develop in
patients with
CKD and
ESRD for many reasons beyond age - related
bone loss and
postmenopausal bone loss . -
pubmed
The diagnosis of
osteoporosis in
patients with severe
CKD or
end - stage renal disease (
ESRD ) is not as easy to do as it is in patients with
postmenopausal osteoporosis (
PMO)--neither
fragility fractures nor The World Health Organization bone mineral density criteria can be used to diagnose
osteoporosis in this population since all forms of
renal bone disease may
fracture or have low " T scores " . -
pubmed
In
patients with stage 5
CKD who are fracturing because of
osteoporosis or who are on chronic glucocorticoids , reducing the oral
bisphosphonate dosage to half of its usual prescribed dosing for
PMO seems reasonable from known
bisphosphonate pharmacokinetics , though we do need better scientific data to fully understand
bisphosphonate usage in this population . -
pubmed
The incidence and severity of
seizures increased with time , reaching a peak 7 - 12 h after
metaphit administration , and then gradually decreased until 31 h , when no
animal responded . -
pubmed
Minimum dose which completely blocked
seizures in all
animals was 0.03 micromole . -
pubmed
The present results demonstrate that
APH acts as anticonvulsant in
metaphit 's model of
audiogenic seizures in
rats . -
pubmed
MATERIALS AND METHODS : Sixty - five
patients with
gastric cancers were preoperatively examined with MDCT using the water - filling method . -
pubmed
Can
paroxetine improve well - being in
patients with
irritable bowel syndrome who do not respond to a high - fiber diet ? -
pubmed
We used transgenic
mouse models of multistep
carcinogenesis to monitor incorporation of bone marrow - derived cells into the neovasculature and to elucidate mechanisms of endothelial precursor cell ( EPC ) recruitment into the
tumor microenvironment . -
pubmed
Athletes and exercise participants may be at increased risk of ocular , oral , and
upper respiratory tract infections . -
pubmed
Glycation free adducts accumulate markedly in the plasma of
uremic patients and are eliminated in the peritoneal dialysate . -
pubmed
Letter regarding article by Weitzman et al , "
tobacco smoke exposure is associated with the
metabolic syndrome in adolescents " . -
pubmed
Quantitative analysis of
poliomyelitis - like
paralysis in
mice induced by a poliovirus replicon . -
pubmed
TgPVR21
mice inoculated with TE - PV - Fluc mc showed non - lethal
paralysis of the hindlimbs , with severity ranging from a decline in grip strength to complete flaccid
paralysis . -
pubmed
These results indicate that
PV replication in a small population of the motor neurons was critical for severe residual
poliomyelitis - like
paralysis in TgPVR21
mice . -
pubmed
Cardiovascular toxicity due to
metoprolol poisoning in a
patient with
coronary artery disease . -
pubmed
RESULTS : Our
patient demonstrated findings of
AMI with
hypotension and
bradycardia that appeared to result from
metoprolol poisoning . -
pubmed
Although one
patient has been reported to have
AMI associated with
metoprolol poisoning , our
patient is unique with her ECG changes and elevated cardiac markers : this is the first time that
AMI characterized by elevated cardiac markers associated with
metoprolol toxicity has been reported . -
pubmed
A total of 90
cancerous and
non - cancerous tissues from 23
patients with
adenocarcinoma and 22 with
squamous cell carcinoma were studied . -
pubmed
Retinal nerve fibre layer measurements and optic nerve head analysis in
multiple sclerosis patients . -
pubmed
PURPOSE : To verify whether scanning laser polarimeter with the new variable corneal compensation algorithm ( GDx VCC ) and scanning laser ophthalmoscopy ( Heidelberg Retina Tomograph ( HRT ) ) allow measuring retinal
ganglion cell loss in
patients with
multiple sclerosis (
MS ) . -
pubmed
PATIENTS AND METHODS : We enrolled 23
MS patients with a history of previous demyelinating monocular
optic neuritis . -
pubmed
The Studio Italiano Sugli Effetti Cardiovascolari del Controllo della Pressione Arteriosa Sistolica ( Cardio - Sis ) is a multi - centre study in non - diabetic , treated
hypertensive subjects aged & gt;55 years with uncontrolled
SBP ( & gt;or=150 mm Hg ) and at least one additional cardiovascular risk factor ( ClinicalTrials.gov identifier : NCT00421863 ) . -
pubmed
We investigated the association between
familial Mediterranean fever (
FMF ) and
osteoporosis (
OP ) in adult
patients . -
pubmed
Thirty - five attack - free
FMF patients ( 28
females , 7
males ; mean age 36.9 + /- 5.7 years ) were individually matched to control subjects on the basis of age ( within 2 years ) and sex . -
pubmed
PARTICIPANTS : Ninety - three
patients referred with
disruptive snoring . -
pubmed
INTERPRETATION : The pars plana lensectomy with double - capsule - supported intraocular lens implantation technique seems to be a safe and easy method in
children , limiting postoperative IOL - related complications and
posterior capsule opacification in the long term . -
pubmed
Lamina reclosure that was evaluated with computed tomography , was observed in 4
patients , but no
spinal cord compression by the closed laminae was observed . -
pubmed
METHOD : Ten
patients with
chronic stroke ( 7
males ; mean age , 61.4+/-3.02 years ; age range , 48 to 79 years ; mean time since
stroke , 28.5 months ; range , 13 to 42 months ) exhibiting stable , affected arm motor deficits were administered mCIT , consisting of : ( 1 ) structured therapy emphasizing affected arm use in functional activities 3 days / week for 10 weeks ; and ( 2 ) less affected arm restraint 5 days / week for 5 hours . -
pubmed
We assessed
tumor growth and weight in the in vivo
nude mice model . -
pubmed
On the other hand , stromal cells of TZ suppressed
PC-3 cell
tumor growth in the
mouse model . -
pubmed
Interestingly , 20 showed broad
cytotoxicity against
human cancer cell lines . -
pubmed
OBJECTIVE : To summarize the clinical data in preventing
HBV recurrence after liver transplantation and explore a optimal individual protocol in prophylaxis of
HBV recurrence . -
pubmed
METHODS : We retrospected outcomes in 195 recipients who underwent a liver transplantation for
HBV - related
liver disease between June 2004 and July 2008 . -
pubmed
At the sixth and eleventh month after operation ,
HBV recurrence appeared in 2 recipients , each in two groups , which were due to
LAM cessation and
HBV mutation respectively . -
pubmed
CONCLUSION :
Lamivudine combined with HBIg should be considered as a reliable method in preventing
HBV recurrence after liver transplantation . -
pubmed
METHODS :
Human atherosclerotic carotid plaques ( n = 29 , 12 associated with symptoms ) were removed by endarterectomy . -
pubmed
These relationships improve understanding of the geographic spread of emerging
diseases , and facilitate the development of methods for predicting and preventing epidemics of plants , animals , and
humans caused by pathogens that are capable of long - distance dispersal . -
pubmed
METHODS : Balb / c
mice underwent a weight drop
TBI . -
pubmed
Selected
mice had electrical stimulation of the cervical vagus nerve before
TBI . -
pubmed
CONCLUSION : In a
mouse model of
TBI , vagal stimulation prevented
TBI - induced intestinal permeability . -
pubmed
An 18 - month male
infant was admitted to our pediatric emergency service due to
poisoning with
amitriptyline . -
pubmed
The
infant 's clinical condition has improved after the
charcoal HP ,
seizures and
SVT were not observed . -
pubmed
Evaluation of light / dark cycle in
anxiety- and
depressive - like behaviors after regular treatment with
methylphenidate hydrochloride in
rats of different ages . -
pubmed
In this context , the present study evaluated the effects of treatment with
methylphenidate hydrochloride on
anxiety- and
depressive - like behaviors using young and adult
rats during the light and the dark cycle . -
pubmed
Clinical presentation and the possible continuous exposure to
wheat seem to suggest a case of
celiac disease . -
pubmed
A 54 - year - old
woman presented with
blepharoptosis ,
numbness in the lower lip ,
dysgeusia and
pain in the extremities and back . -
pubmed
We performed a meta - analysis of randomized clinical trials using blood pressure - lowering medications , used in patients with
hypertension ,
myocardial infarction , or
left ventricular systolic dysfunction , ( n=18 ; 132 854
patients ; 11 988
deaths ) when a second report describing results after the end of the trial was available . -
pubmed
Risk factors associated with prevalence of
tuberculosis - like lesions and associated mycobacteria in
cattle slaughtered at public and export abattoirs in Ethiopia . -
pubmed
Urinary excretion of
3 - hydroxyisovaleryl carnitine is an early and sensitive indicator of marginal
biotin deficiency in
humans . -
pubmed
Marginal , asymptomatic
biotin deficiency was induced experimentally in the same 10 healthy
adults ( 8
women ) by feeding undenatured egg white with meals for 28 d.
Biotin status was repleted by a mixed general diet plus
biotin supplementation . -
pubmed
High susceptibility to
Chikungunya virus of
Aedes aegypti from the French West Indies and French Guiana . -
pubmed
OBJECTIVES : To estimate the vector competence of
Aedes aegypti populations sampled from distinct anthropogenic environments in French Guiana , Guadeloupe and Martinique for the
strain CHIKV 06.21 . -
pubmed
Importantly , studies in the preterm
baboon have shown that nephrogenesis is clearly ongoing following
preterm birth ; however , the presence of abnormal glomeruli ( up to 18 % in some cases ) is of concern . -
pubmed
Small intestinal
strangulation caused by a mesodiverticular band and
diverticulum on the mesenteric border of the small intestine in a
horse . -
pubmed
A 4 - year - old Quarter
horse stallion was presented for acute
abdominal pain . -
pubmed
Human respiratory syncytial virus (
RSV ) constitute highly pathogenic virus that cause severe
respiratory diseases in newborn , children , elderly and immuno - compromised individuals . -
pubmed
Airway inflammation is a critical regulator of disease outcome in
RSV infected hosts . -
pubmed
The inaugural Translational Science article in this month 's issue is fron Santhiago and colleagues on short - term cell
death and
inflammation after intracorneal inlay implantation in
rabbits . -
pubmed
Evaluation of rib microstructure in
Wistar rats using SR - muCT after radiation therapy simulation for
breast cancer . -
pubmed
Treatment outcome of intravenous
artesunate in
patients with severe
malaria in the Netherlands and Belgium . -
pubmed
This is the largest case series of
artesunate treated
patients with severe
malaria in Europe . -
pubmed
RESULTS : Of the 68 treated
patients , including 55 with severe
malaria , two
patients died ( 2/55 = 3.6 % ) . -
pubmed
However , an unusual form of
haemolytic anaemia was observed in seven
patients . -
pubmed
Mother to child transmission of
HIV -- another complication of
bacterial vaginosis ? -
pubmed
Diagnostic performance of P wave duration in the identification of
left atrial enlargement in
dogs . -
pubmed
OBJECTIVES : To determine sensitivity and specificity of P wave duration in the identification of
left atrial enlargement in
dogs . -
pubmed
METHODS : Electrocardiograms from normal
dogs and
dogs with various
cardiovascular diseases were evaluated . -
pubmed
CLINICAL SIGNIFICANCE : The diagnostic performance of P wave duration for identification of left
atrial enlargement in
dogs presents considerable limitations . -
pubmed
METHODS : 151
adolescents with
T1DM ( mean age 14.9 + - 1.7 years ) and a comparison group ( n = 122 ) reported their
depressive symptoms and behavior problems . -
pubmed
Differential diagnoses for
canine liver disease are commonly based on radiographic estimates of liver size , however little has been published on breed variations . -
pubmed
Aims of this study were to describe normal radiographic liver size in Pekingese
dogs and to compare normal measurements for this breed with other
dog breeds and Pekingese
dogs with
liver disease . -
pubmed
Liver measurements were compared for clinically normal Pekingese ( n = 61 ) , normal non - Pekingese brachycephalic ( n = 45 ) , normal nonbrachycephalic ( n = 71 ) , and Pekingese breed
dogs with
liver disease ( n = 22 ) . -
pubmed
Normal Pekingese
dogs had a significantly smaller liver volume /
body weight ratio ( 16.73 + - 5.67 , P & lt ; 0.05 ) than normal non - Pekingese brachycephalic breed dogs ( 19.54 + - 5.03 ) and normal nonbrachycephalic breed dogs ( 18.72 + - 6.52 ) . -
pubmed
Improved blood pressure control with
nifedipine GITS /
valsartan combination versus high - dose
valsartan monotherapy in mild - to - moderate
hypertensive patients from Asia : results from the ADVISE study , a randomized trial . -
pubmed
AIMS : ADVISE was a 12 - week , multicenter , randomized , prospective , open - label , parallel - group study comparing combination therapy of
nifedipine GITS 30 mg plus
valsartan 80 mg ( N + V ) with high - dose
valsartan ( 160 mg ) monotherapy ( V160 ) in Asian
patients with
hypertension . -
pubmed
METHODS :
Patients with
hypertension inadequately controlled with
valsartan 80 mg for at least 4 weeks were randomized . -
pubmed
Therefore , our
zebrafish model provides a powerful in vivo tool for the investigation of
tumor - induced angiogenesis , and a cost - effective system for high - throughput screening of anti - angiogenic compounds . -
pubmed
In this study , a case of endogenous
bacterial endophthalmitis , associated with
methicillin - resistant
Staphylococcus aureus bacteremia , is presented . -
pubmed
METHODS : A total of 11549 subjects were evaluated , and 4951
patients ( 42.8 % ) reported
headaches . -
pubmed
The 1 - year
headache prevalence was 38.6 % in
children , 47.0 % in adults , and 23.3 % in the elderly ( p<0.001 ) . -
pubmed
The female to male ratio was higher in adults ( p<0.001 ) and elderly
headache patients ( p<0.001 ) , but not in children ( p=0.654 ) . -
pubmed
Two trials of 30 and 48
hypothyroid women respectively compared
levothyroxine doses , but both trials reported only biochemical outcomes . -
pubmed
A trial of 169
women compared the trace element
selenomethionine (
selenium ) with placebo and no significant differences were seen for either pre -
eclampsia ( RR 1.44 ; 95 % CI 0.25 to 8.38 ) or
preterm birth ( RR 0.96 ; 95 % CI 0.20 to 4.61 ) . -
pubmed
In a controlled randomized clinical trial , 55
patients with chronic
tinnitus were randomly divided in two groups . -
pubmed
METHODS AND PROCEDURES : Male
Wistar rats received
ischaemic damage using a transient , focal
ischaemia / reperfusion model . -
pubmed
Small bowel follow - through ( SBFT ) is a diagnostic tool commonly used in the management of
patients with
small bowel obstruction (
SBO ) . -
pubmed
In this retrospective chart review , 103
patients with the clinical diagnosis of adhesive
SBO were evaluated . -
pubmed
There were 103
patients with adhesive
SBO who met inclusion criteria for this study . -
pubmed
Obtaining Gastrografin SBFT in
patients with adhesive
SBO leads to both a shorter time in identifying the need for operative intervention and to resolution of SBO with nonoperative management . -
pubmed
PURPOSE : To evaluate the correlation between different fusional convergence parameters and the Newcastle Control Score ( NCS ) in
children with
intermittent exotropia . -
pubmed
METHODS : In this consecutive prospective observational series , 101 Chinese
children with
intermittent exotropia were examined by a single observer , who assessed the level of control using the revised NCS and measured the angle of deviation and fusional convergence . -
pubmed
CONCLUSIONS : In
children with
intermittent exotropia , the total convergence amplitude was similar among different levels of control . -
pubmed
UNLABELLED :
Rhabdomyosarcoma is the most common
soft tissue sarcoma in
children . -
pubmed
Interaction between myelomonocytic and lymphoid cells in a
patient with
acute myelomonocytic leukemia and
chronic lymphocytic leukemia . -
pubmed
Medical resource use , costs , and quality of life in
patients with acute decompensated
heart failure : findings from ASCEND -
HF . -
pubmed
Because
pain ,
swelling and
muscle spasm are complications found in virtually all
patients following oral surgery for the removal of impacted teeth , this model has been widely used to evaluate the effects of LLLT on the inflammatory process involving bone and , connective tissue and the muscles involved in mastication . -
pubmed
At 2 and 7 days after surgery , the
patients will be evaluated by three blinded evaluators who will measure of
swelling , mouth opening (
muscle spasm evaluation ) and
pain ( using two different
pain scales ) . -
pubmed
The present study aims to provide a randomized , controlled , double - blind trial to compare four different LLLT parameters in relation to the outcomes of
pain ,
swelling and
muscle spasm following surgery for the extraction of impacted third molars and evaluate the effects os surgery on
patients ' quality os life ( QOL ) . -
pubmed
METHODS : Psychotropic drug use in 196
YOD patients was registered . -
pubmed
STUDY OBJECTIVES : The primary objective was to systematically review the literature on how
sleep disordered breathing (
SDB ) affects
recurrence and
death among
stroke or
transient ischemic attack (
TIA )
patients . -
pubmed
METHODS :
Adults ( 18 + ) with a
stroke or
TIA diagnosis were eligible for inclusion . -
pubmed
RESULTS : Ten articles covering 1,203
stroke and
TIA patients were included in the review . -
pubmed
The results generally support a dose - response relationship between severity of
SDB and risk of recurrent events and all - cause mortality in
stroke and
TIA patients . -
pubmed
Intolerance to
sunitinib treatment in hemodialysis
patients with
metastatic renal cell carcinoma . -
pubmed
However , neither an appropriate dose nor dosing schedule of
sunitinib has yet been established for
patients with
metastatic RCC who are on hemodialysis . -
pubmed
Here , we report on two hemodialysis
patients who received
sunitinib to treat
metastatic RCC . -
pubmed
Although
sunitinib toxicity was manageable in one
patient ,
disease progression occurred after 4 months of treatment . -
pubmed
In the second
patient ,
acute pulmonary edema , caused by uncontrolled
hypertension , developed on the 15th day of
sunitinib therapy and the drug had to be discontinued . -
pubmed
[ Transpleural bronchotomy in the treatment of certain
foreign bodies in
children ] . -
pubmed
Sulfated - polysaccharide fraction extracted from
red algae Gracilaria birdiae ameliorates
trinitrobenzenesulfonic acid - induced
colitis in
rats . -
pubmed
OBJECTIVES : The aim of this study was to evaluate the protective effect of the sulfated - polysaccharide ( PLS ) fraction extracted from the seaweed
Gracilaria birdiae in
rats with
trinitrobenzenesulfonic acid (
TNBS)-induced
colitis . -
pubmed
METHODS : In the experiments involving TNBS - induced
colitis ,
rats were pretreated with polysaccharide extracted from
G. - pubmed
Image diagnosis of
zoonotic onchocercosis by
Onchocerca lupi . -
pubmed
, ultrasound scan , computed tomography and magnetic resonance imaging ) are herein used to diagnose
canine onchocercosis in two
dogs , which scored positive for
O. - pubmed
lupi in
dogs and to evaluate the localization of nodules or
cysts containing the adult nematode . -
pubmed
After percutaneous coronary intervention ( PCI ) including anticoagulation ,
comatose patients are sedated for mild therapeutic
hypothermia . -
pubmed
BACKGROUND :
Staphylococcus aureus is a leading cause of
nosocomial infections . -
pubmed
Complement functional tests for monitoring
eculizumab treatment in
patients with atypical
hemolytic uremic syndrome . -
pubmed
OBJECTIVES : To optimize
eculizumab therapy in
aHUS patients by monitoring complement functional tests and markers of disease activity . -
pubmed
PATIENTS / METHODS : We studied 18
patients with
aHUS ( 10
males ; eight
females ; age range , 2 - 40 years ) treated with eculizumab to induce and/or maintain disease remission . -
pubmed
gondii
strains from
sheep and
goats slaughtered in East and West Shewa Zones of Oromia Regional State , Central Ethiopia . -
pubmed
gondii tissue
cysts in
sheep and
goats slaughtered for
human consumption are widespread . -
pubmed
RESULTS : Two
women and a
man presented with of
exophthalmos and
diplopia . -
pubmed
Pain was the most prominent complaint in 2
patients . -
pubmed
None of the
patients had associated
systemic neurofibromatosis by history or examination . -
pubmed
CONCLUSIONS : Multiple
orbital schwannomas (
primary orbital schwannomatosis ) may be observed in
patients without systemic association of
neurofibromatosis . -
pubmed
Sublethally irradiated NOD / Shi - scidIL2rgamma(null )
mice transplanted with
human umbilical cord blood ( HuCB
mice ) gradually developed clinical signs of
graft - versus - host disease (
GVHD ) such as loss of weight ,
ruffled fur , and
alopecia . -
pubmed
Bacterial resistance has been increasingly reported worldwide and is one of the major causes of failure in the treatment of
infectious diseases . -
pubmed
METHODS : Consecutive
patients ( n=18 ) who had undergone successful vitrectomies for
idiopathic macular holes were evaluated postoperatively at 1 , 3 , 6 and 9 months . -
pubmed
METHODS : This is a descriptive , cross - sectional study on 220
diabetic patients using herbal remedies for perceived glycemic benefit . -
pubmed
We examined whether genetic loci previously associated with
depressive symptoms predict
depressive symptoms among
overweight / obese
individuals with
Type 2 diabetes or change in
depressive symptoms during behavioral
weight loss . -
pubmed
The American Academy of Pediatrics recommends screening
children with
HTN for
sleep disorders because
sleep disorders increase the risk for
cardiovascular disease . -
pubmed
METHODS : Seventy - one
patients who underwent arthroscopic suturing of
SLAP lesions between July 1995 and May 2008 were evaluated . -
pubmed
Associated lesions were seen in 68 of the 71
patients evaluated ( 96 % ) , and the other three ( 4 % ) had
SLAP lesions alone . -
pubmed
RESULTS : The associated lesions most frequently found in the
patients under 40 years of age were
labral lesions ( 69 % ) , while in
patients aged 40 years or over , impact
syndrome with or without
rotator cuff injury was the most commonly associated condition ( 71.4 % ) . -
pubmed
CONCLUSIONS : There was a great association between
SLAP lesions and other
shoulder lesions , which varied according to the
patients ' age groups . -
pubmed
METHODS : Forty
PD patients and 40
NC were recruited in this study . -
pubmed
MATERIAL AND METHODS : Rapid acquisition with relaxation enhancement , spin echo and gradient echo fast low angle shot data were acquired using ex vivo 3 - Tesla or 7 - Tesla magnetic field strengths from fresh prostatectomy specimens ( n = 15 ) obtained from either organ donor or
patients with
prostate cancer (
PCa ) . -
pubmed
This study reviewed the medical records of 90
patients with
lipomas ( 47
patients ) and atypical
lipomatous tumors ( ALT)/well - differentiated
liposarcomas (
WDL ) ( 43
patients ) of the extremities treated from 2006 to 2012 . -
pubmed
All
patients had preoperative biopsy and postoperative histologic analysis of the
tumors ;
surgical margins were marginal in all cases . -
pubmed
Local
recurrence and
metastasis rates and the relationship of
patient age and sex with
tumor size and location were evaluated . -
pubmed
None of the
patients with
lipomas experienced local recurrence compared with 6
patients ( 13.9 % ) with ALT / WDL who experienced local
recurrence within a mean of 48 months ( range , 33 - 96 months ) ; this difference was statistically significant . -
pubmed
None of the
patients in either group experienced
metastasis prior to the study period . -
pubmed
Local
recurrence did not correlate statistically with
patient age or sex , or with
tumor size or location . -
pubmed
[
Rehmanniae Radix and
Rehmanniae Radix Praeparata Ameliorates
Renal Interstitial Fibrosis Induced by Unilateral
Ureteral Occlusion in
Rats and Their Mechanism ] . -
pubmed
OBJECTIVE : To study the effects of
Rehmanniae Radix and
Rehmanniae Radix Praeparata on
renal interstitial fibrosis (
RIF ) of obstructed kidneys in a
unilateral ureteral obstruction (
UUO )
rat model and the mechanism . -
pubmed
MATERIALS AND METHODS : A total of 92
patients with confirmed diagnosis of
CCHF in 2009 - 2013 were included in the study . -
pubmed
Metformin , a well - known anti - diabetic agent , is very effective in lowering blood
glucose in
patients with
type 2 diabetes with minimal side - effects . -
pubmed
However , since
metformin is eliminated unchanged through the kidneys and some studies have shown the incidence of
lactic acidosis with its use during severe
renal dysfunction , the use of
metformin was contraindicated in
patients with
renal disease until recently . -
pubmed
With more studies indicating the relatively low incidence of
lactic acidosis and revealing the additional benefits with
metformin therapy , the US FDA has now approved
metformin to be administered in
patients with established
renal disease based on their renal function . -
pubmed
The purpose of this review is to highlight the various mechanisms by which
metformin protects renal cells that have lost its functionality in a
diabetic or non - diabetic setting and to enlighten the advantages and therapeutic potential of
metformin as a nephroprotectant for
patients with
diabetic nephropathy and other non - diabetic forms of
chronic kidney disease . -
pubmed
Therefore , we have investigated here whether and how CA would prevent
paraquat ( PQ)-induced
inflammation - related alterations in
human neuroblastoma SH - SY5Y cells . -
pubmed
CASE : Five years ago , a 12 - year - old
patient underwent linear lens extraction , posterior capsulotomy , and anterior vitrectomy due to traumatic
cataract and received a
polymethyl methacrylate (
PMMA ) biconvex posterior chamber IOL implanted in ciliary sulcus . -
pubmed
Genome - wide DNA methylation analysis during
non - alcoholic steatohepatitis - related multistage hepatocarcinogenesis : comparison with
hepatitis virus - related
carcinogenesis . -
pubmed
Principal component analysis using the 3331 probes revealed distinct DNA methylation profiles of
NASH - N samples that were different from those of
NLT samples and 37 samples of
non - cancerous liver tissue showing
chronic hepatitis or
cirrhosis associated with
hepatitis B virus (
HBV ) or
hepatitis C virus ( HCV ) infection ( viral - N ) . -
pubmed
We aimed to investigate whether sigma-1 antagonism reduces inflammatory
pain through the disinhibition of the endogenous opioidergic system in
mice . -
pubmed
The selective sigma-1 antagonists
BD-1063 and
S1RA abolished mechanical and thermal
hyperalgesia in
mice with carrageenan - induced acute ( 3 h )
inflammation . -
pubmed
These technologies provide tools for treating the many forms of
amyloid disease , restoring organ function and enhancing
patient survival . -
pubmed
Human papillomavirus ( HPV ) testing is increasingly being incorporated into
cervical cancer screening . -
pubmed
Cerebral mycotic aneurysms secondary to
Streptococcus Agalactiae induced
infective endocarditis . -
pubmed
Streptococcus agalactiae , is a rare cause of
endocarditis and there are no reported cases of
cerebral mycotic aneurysms secondary to this organism . -
pubmed
We report a rare case of
streptococcus agalctiae induced
intracranial mycotic aneurysm . -
pubmed
Introduction : We report on a rare case of a
man with bowel
rupture due to direct
trauma to his diagnosed
inguinal hernia , with reviewing the relevant literature , we have found some characteristics of our case different from the similar cases reported by other authors . -
pubmed
Presentation of the case : A 54 - year - old
man , with a dignosed right
inguinal hernia without treatment for over six months , presented to our hospital with generalized
peritonitis and possible
sepsis , caused by minimal hit directly to his
hernia . -
pubmed
Maternal imprinting on cognition markers of wild type and transgenic
Alzheimer ' s disease model
mice . -
pubmed
The risk of suffering from
Alzheimer ' s disease (
AD ) is higher in
individuals from
AD - affected mothers . -
pubmed
The purpose of this investigation was to study whether maternal transmission might produce
AD - related alterations in progenies of
mice that do not have any genotypic alteration . -
pubmed
Platelet - rich plasma on female
androgenetic alopecia : Tested on 10
patients . -
pubmed
AIMS : Investigate the efficacy , tolerability , and clinical improvement of PRP for the treatment of
female AGA . -
pubmed
PATIENTS / METHODS : A total of 10 female
patients affected by
AGA and not responding to treatment with
minoxidil and/or oral antiandrogens were enrolled . -
pubmed
Children and youth are disproportionally affected by
concussion , and once injured , take longer to recover . -
pubmed
Safety of dose - reduced
pemetrexed in
patients with
renal insufficiency . -
pubmed
In this population ,
renal insufficiency is common ; however ,
pemetrexed is not recommended in
patients with a
creatinine clearance ( CrCl ) & lt ; 45 ml / min due to increased
myelosuppression reported in phase I trials . -
pubmed
METHODS : This is a retrospective case series describing the incidence of grade 3 or higher
toxicity in
patients with CrCl & lt ; 45 ml / min treated with dose - reduced
pemetrexed at The James Cancer Hospital and Solove Research Institute at The Ohio State University . -
pubmed
Four ( 22 % )
patients had grade & gt;= 3
hematologic toxicity ; three of which were receiving concomitant
platinum agents . -
pubmed
No
patients receiving single - agent
pemetrexed with a CrCl & gt ; 30 ml / min experienced grade & gt;= 3
hematologic toxicity . -
pubmed
Folded extended vertical lower trapezius island myocutaneous flaps ( TIMFs ) were created to repair large
PCFs that developed after salvage total laryngectomy in eight
patients . -
pubmed
After 6 - 24months of follow - up , six
patients showed no evidence of disease , one was alive with disease , and one had died of local
recurrence at 20months . -
pubmed
Polyclonal antibodies to
Paracoccidioides brasiliensis are able to recognise antigens from different
strains from Paracoccidioides species complex , including
Paracoccidioides lutzii LDR2 . -
pubmed
Since the new species
Paracoccidioides lutzii emerged in 2009 , much has been researched on
strains previously considered atypical . -
pubmed
brasiliensis Pb18 ; ( c)IB and ELISA with a pool of
PCM patients ' sera before and after treatment with
sodium metaperiodate (
SMP ) to oxidise
carbohydrate epitopes . -
pubmed
A total of 263 PV
strains were isolated , including 22
strains of
type 1 PV , 104
strains of
type 2 PV , and 137
strains of
type 3 PV . -
pubmed
As a result of intratypic differentiation , using real - time PCR and nucleotide sequencing , 3 type 1
pre - VDPV , one type 2
VDPV , and 2
type 3 pre - VDPV strains were isolated . -
pubmed
Transcatheter closure and conservative management has been described for select
patients with iatrogenic
fistulas in recent literature . -
pubmed
The
TGD - treated
rats had lower rates of
AF inducibility and shorter
AF durations than the
MI rats . -
pubmed
RESULTS : A total of 109
patients ( mean age 64 years , range 19 - 85 ; 66 % male , 38 % never smokers ) referred to our center with features suggestive of
ILD underwent cTBB . -
pubmed
CONCLUSIONS : In the real - world setting , cTBB has a meaningful diagnostic value in the context of a MDT approach and may enable histopathological assessment even in
patients with more advanced disease unsuitable for
SLB . -
pubmed
Delayed ACL Reconstruction in
Patients & gt;=40 Years of Age Is Associated With Increased Risk of Medial
Meniscal Injury at 1 Year . -
pubmed
PURPOSE : : To evaluate whether delayed reconstruction in a cohort of
patients aged & gt;=40 years is associated with an increased risk of
meniscal or chondral injury . -
pubmed
Medial , lateral , and patellofemoral compartment
chondral injury was reported in 127 , 82 , and 130
patients , respectively . -
pubmed
CONCLUSION : : Delayed ACL reconstruction ( & gt;=90 days ) among
patients aged & gt;=40 years was not associated with an increased risk of
meniscal or chondral injury . -
pubmed
Impact of
atrial fibrillation on in - hospital mortality of
ischemic stroke patients and identification of promoting factors of
atrial thrombi - Results from the German nationwide inpatient sample and a single - center retrospective cohort . -
pubmed
We aimed to investigate the impact of
AF on in - hospital mortality of
ischemic stroke patients and to identify parameters associated with intra - cardiac thrombogenic material . -
pubmed
The inheritance of resistance to the foliar phase of
bacterial blight disease , caused by
Xanthomonas axonopodis pv . - pubmed
The other occurred in a 25 - year - old
patient , was 18 cm wide , and was diagnosed as a well - differentiated
neuroendocrine tumor , World Health Organization grade 3 . -
pubmed
MAIN BODY : Evidences of the impact of climate change are available for
malaria ,
arbovirus diseases such as
dengue , and many other parasitic and
viral diseases such as
Rift Valley Fever ,
Japanese encephalitis ,
human African
trypanosomiasis and
leishmaniasis . -
pubmed
CONCLUSIONS : In this paper we discuss the current state of the results and draw on evidences from
malaria ,
dengue and other vector - borne diseases to illustrate the state of current thinking and outline the need for further research to inform our predictions and response . -
pubmed
Thrombocytopenia is commonly seen in
patients receiving
linezolid for & gt;14 days . -
pubmed
Given the dynamics of platelet production and destruction , these results may explain why
oxazolidinone - induced
thrombocytopenia emerges as one of the most frequent untoward effects in
patients exposed to these antibiotics . -
pubmed
A 41 - year - old
woman presented with a
recurrence of
myxoinflammatory fibroblastic sarcoma on the medial part of the left foot dorsum . -
pubmed
Gut Microbial Metabolite
Trimethylamine N - Oxide Is Related to
Thrombus Formation in
Atrial Fibrillation Patients . -
pubmed
Patients with
AF are prone to forming
cardiac thrombi . -
pubmed
No previous studies have examined the relationship between serum
TMAO levels and
thrombus formation in
AF patients . -
pubmed
MATERIALS AND METHODS : A total of 117 consecutive
rheumatic heart disease patients with
AF were enrolled . -
pubmed
The
patients were divided into 2 groups :
patients with
thrombi ( n = 25 ) and
patients without
thrombi ( n = 92 ) . -
pubmed
CONCLUSIONS : Elevated serum
TMAO levels were predictive of
thrombus formation in
AF patients . -
pubmed
Our results highlight the usefulness of serum
TMAO levels in identifying
individuals with increased susceptibility to
thrombus formation , allowing development of precise
thrombus prevention strategies . -
pubmed
Cytomegalovirus (
CMV ) is one of the major
human health threats worldwide , especially for immunologically comprised patients . -
pubmed
The etiology of
brain diseases associated with human
CMV ( HCMV ) infections is usually complex and it is particularly difficult to treat because
HCMV has a life - long
infection in its hosts , high mutation rate , and
latent infections . -
pubmed
For the treatment of
glioblastoma , vaccine therapy through targeting specific
CMV antigens has improved
patients ' survival outcomes significantly and immunotherapy has also emerged as an alternative modality . -
pubmed
The advanced research for developing anti -
CMV agents and approaches is promising to obtain significant outcomes and expecting to have a great impact on the therapy of
brain diseases associated with
CMV infections . -
pubmed
METHODS : The WAIS - III profiles of 50
adults with
ADHD were compared to an age - matched typical development ( TD ) group . -
pubmed
All
patients with
NOA who underwent TESE during their fertility treatments were included . -
pubmed
The development of gradient - boosted trees ( GBTs ) aimed to predict the presence or absence of spermatozoa in
patients with
NOA . -
pubmed
OBJECTIVE : To determine the diagnostic accuracy of the CPOT in
critically ill patients , a systematic review of diagnostic studies was performed . -
pubmed
SETTING : Fuwai Hospital , National Center for
Cardiovascular Disease , Beijing , China PARTICIPANTS : Consecutive
patients with successfully recanalised CTO were included from January 2010 to December 2013 . -
pubmed
CONCLUSION :
Patients with long CTO lesion did not show a higher risk of
death and
MI after recanalisation , but had higher risks of TLR and TVR . -
pubmed
The Effect and Optimal Dosage of
Dexmedetomidine Plus
Sufentanil for Postoperative Analgesia in Elderly
Patients With
Postoperative Delirium and Early Postoperative
Cognitive Dysfunction : A Single - Center , Prospective , Randomized , Double - Blind , Controlled Trial . -
pubmed
Background :
Postoperative delirium (
POD ) and
postoperative cognitive dysfunction (
POCD ) are common complications after major surgery among elderly
patients . -
pubmed
Dexmedetomidine (
DEX ) is less frequently explored for its effects in
patients with
postoperative neurocognitive disorders . -
pubmed
This study investigated the effect and optimal dosage of
DEX for
patient - controlled analgesia ( PCA ) on POD and early
POCD after major surgery among elderly
patients . -
pubmed
Compared with
DEX 200 mug ,
DEX 400 mug reduced early
POCD in
patients who underwent open surgery ( P < 0.05 ) . -
pubmed
Compared with
DEX 200 mug ,
DEX 400 mug was preferred for reducing early
POCD in
patients who underwent open surgery . -
pubmed
Evaluation of quality of life in
patients surgically treated for potentially malignant
oral lesions . -
pubmed
This study aimed to evaluate the postoperative QOL of surgically treated
patients for
OPMDs . -
pubmed
Materials and Methods : It was a cross - sectional study done on 45 follow - up
patients , aged 24 - 80 years , who were surgically treated for
OPMDs . -
pubmed
Importantly , 20 % to 30 % of
mice were even long - term protected and did never develop clinical signs of
tumor growth . -
pubmed
CONCLUSIONS :
Tumor cell senescence may explain why
patients responding to immune checkpoint blockade frequently show stable growth arrest of
tumors rather than complete
tumor regression . -
pubmed
The clinical severity , rapid transmission and
human losses due to
coronavirus disease 2019 ( Covid-19 ) have led the World Health Organization to declare it a pandemic . -
pubmed
Relationship of diffusion tensor imaging parameters with
neurocognitive dysfunction in
patients with
Behcet ' s disease . -
pubmed
Thirty - five
adults with
Behcet ' s disease and 21 age - matched healthy controls were enrolled in this study . -
pubmed
The incidence of
gastro - intestinal carcinomas in
man is rather high as compared to other organ systems ; results of cytostatic or x - ray therapy of these
tumors , however , on the other hand are rather poor . -
pubmed
Controlled prospective clinical studies are needed in the future in order to elucidate the role of additional cytostatic therapy in
patients with
malignant tumors of the gastro - intestinal tract . -
pubmed
Electroencephalographic and behavioral study of the
cat 's reactivity to stimuli during the evolution of
cobalt amygdaloid epilepsy . -
pubmed
Experimental
chronic polyarthritis in
mice . -
pubmed
For 53
patients with
toxic recurrent goiter (
TRG ) , the interval between thyroidectomy and recurrent
hyperthyroidism range from six months to 50 years ( average , 12.4 + /- 11.9 years ) . -
pubmed
Recurrent
hyperthyroidism may occur in older
patients for whom
cardiac decompensation may be the initial manifestation . -
pubmed
Reports on surgically treated
hyperthyroid patients may underestimate the incidence of
TRG unless follow - up is extended for many years . -
pubmed
Seven
patients had clinically benign , asymptomatic lesions measuring less than 2 cm in diameter that were devoid of
necrosis . -
pubmed
The eighth
patient had a symptomatic , partially necrotic
CCTL 4.5 cm in diameter that metastasized to the liver and peritoneum ; the
patient died of
tumor 17 years after diagnosis . -
pubmed
Cardiac arrest and resuscitation alters the pharmacokinetics of
MK-801 in the
rat . -
pubmed
The therapeutic diagnostic level is shown for this type of
iatrogenic impotence and the various therapeutic possibilities are pointed out in relation to the wishes of the
patient and to his life expectancies . -
pubmed
Ticarcillin- and
tobramycin - resistant
strains of
Pseudomonas aeruginosa were shown to have a markedly increased sensitivity to antibiotics enclosed in liposomes . -
pubmed
A long - term follow - up study of
maxillary clefts operated on primarily with the maxillary periosteal flap ( 67
patients ) and the free tibial periosteal graft ( 23
patients ) showed a definite bone bridge in 64 versus 85 percent of the
patients . -
pubmed
Coronary angioplasty was used without surgical back - up in eight
patients with
angina refractory to medical therapy . -
pubmed
Cytotoxic action of
adenosine nucleoside and
dialdehyde analogues on
murine neuroblastoma in tissue culture : structure - activity relationships . -
pubmed
A series of
purine nucleoside and
dialdehyde analogues was studied to determine their potency as inhibitors of
C-1300 murine neuroblastoma cell growth in tissue culture . -
pubmed
Nasomaxillary fibrosarcomas in three young
horses . -
pubmed
Nasomaxillary fibrosarcoma was diagnosed in 3 young
horses . -
pubmed
Selective nephroangiography in the
dog causing renal
platelet aggregation and irregular nephrographic phase . -
pubmed
These effects were followed by
tubular damage , which was demonstrated in 4 of 6
dogs examined 48 hours after injection . -
pubmed
Formation of
thrombi was not demonstrated in 6
dogs given small single doses , which produced a homogeneous nephrographic phase . -
pubmed
Uptake of radiopharmaceutical was markedly abnormal in all phases of the bone scan in the feet of
patients with
diabetic neuropathy . -
pubmed
Bone scans were performed in three groups of
patients ;
diabetics with
neuropathic osteoarthropathy (
Charcot joints ) ;
diabetics with
neuropathy but no evidence of
osteoarthropathy and non - diabetic controls . -
pubmed
Uptake was monitored in three phases ; during the first 2 min after injection , then at 4 min and finally at 4 h. Uptake in all three phases was markedly increased in the
neuropathic subjects , not only in those with
osteoarthropathy but also in those with no radiological abnormalities . -
pubmed
[ Development of protoscolices of
echinococcus multilocularis in experimentally infected
mice in dependence on age and sex of the experimental animals and on
infection --prerequisites for the development of a test model ] . -
pubmed
Long - term
methylphenidate treatment of
hyperkinetic children . -
pubmed
The test revealed a significant increase in titre of antibodies in
patients with the allergic or mycetomal forms of
pulmonary aspergillosis . -
pubmed
[ Level of
histamine in peripheral blood in
patients with
bacterial shock ] . -
pubmed
Slow reacting substance in the exudate of
allergic air pouch inflammation in
rats . -
pubmed
The activity of slow reacting substance was examined in the exudate of the
allergic inflammation in
rats after partial purification by alkaline decomposition and XAD-8 anion - exchange column chromatography . -
pubmed
The distributions of platelet volume and density were measured in 15
men suffering
myocardial infarction and in 22 healthy controls . -
pubmed
Octanol / water partition coefficients were determined and the antimicrobial activity assessed as the minimum growth inhibitory concentrations towards twelve
strains of micro - organisms , representative of Gram - negative and Gram - positive bacteria ,
yeasts and
fungi . -
pubmed
Since fetal
decapitation in the
pig hardly influences ovarian development , pituitary dependency of the fetal ovary in the
pig is unlikely . -
pubmed
Two
children with apparent
brain abscesses were cured with antibiotic therapy . -
pubmed
The clinical application of the different
tumor markers for early diagnosis , staging and therapy control of
lung cancer patients is described . -
pubmed
A
patient with a
carcinoid syndrome due to
liver metastases is described . -
pubmed
Continuous negative external chest pressure decreases transvascular lung water transport in
sheep after Pseudomonas
bacteremia . -
pubmed
We studied the effects of continuous negative external chest pressure ( CNECP ) produced by a cuirass appliance on lung water and protein transport in
sheep with
chronic lung lymphatic fistulas . -
pubmed
We conclude that CNECP mechanically reversed the
PVPD in our group III
sheep . -
pubmed
These physiologic effects of CNECP may be of benefit in the management of
patients with adult
respiratory distress syndrome . -
pubmed
PATIENTS AND METHODS : In 70 ( 56 % ) of 125 examined
patients with central
retinal vein occlusion laser treatment was performed . -
pubmed
After laser treatment 3 ( 9 % )
patients with
ischemic CRVO developed
iris neovascularization and 2 ( 6 % )
neovascular glaucoma . -
pubmed
CONCLUSIONS : The results of this study indicate that there is no significant visual improvement in
patients with
CRVO after laser treatment . -
pubmed
We describe three
patients with four thumbs in which scapho - trapezoid
osteoarthritis was associated with
basal joint arthritis . -
pubmed
In the other
patients , the scapho - trapezoid joint was excised primarily , with resolution of the
pain . -
pubmed
We describe a case of a severe
Cushing syndrome developed in a 51 - year - old
man . -
pubmed
Although the treatment with
SMS-201 - 995 octreotide was effective in controlling the clinical symptoms , the
patient died three months later with extensive
metastases . -
pubmed
DNA - damaging potency and
genotoxicity of
aflatoxin M1 in somatic cells in vivo of
Drosophila melanogaster . -
pubmed
Metabolism of
serotonin was studied in pineal gland of
Wistar rats with low and high rate of audio excitability as well as in the Krushinsky - Molodkina
rat population genetically predisposed to audio - dependent
convulsions . -
pubmed
Intensive turnover of
serotonin via
N - acetyl serotonin into
melatonin was found in pineal gland of
rats insensitive to sensory stimulus , whereas the rate of this response was decreased in the gland tissue of
animals sensitive to audio effects as well as inhibition of
serotonin turnover into
melatonin was noticed in pineal gland of
rats predisposed genetically to audio - dependent
convulsions . -
pubmed
[ Genomic changes in
strains of the
tick - borne encephalitis virus as a result of passages in
mice ] . -
pubmed
Changes in genomes of
TBE strains isolated from various sources at early stages of laboratory adaptation to white
mice brain were demonstrated by molecular hybridization of nucleic acids with synthetic oligonucleotide probes , complementary RNA sites of reference
TBE strains Sofyin and Neudorf . -
pubmed
Of the 4
TBE strains passed 6 times through white
mice brain in only 1 the level of RNA hybridization with 2 oligonucleotide probes was found changed , whereas in all the 3 tested strains the level of RNA hybridization with 1 - 2 oligonucleotide probes complementary to strain Sofyin was increased after 7 - 16 passages in the same system . -
pubmed
METHODS : Bone mineral density ( gm / cm2 ) at the lumbar vertebrae ( L1 - L4 ) and at the left femur ( neck , trochanter , intertrochanter , and Ward 's triangle ) was measured by dual x - ray absorptiometry in 46
SLE patients ( mean age 31 years , mean disease duration 76 months ) and in 108 healthy female controls ( mean age 32 years ) . -
pubmed
Twenty - three Danish clinical
strains from 23 patients phenotypically identified to the
A. - pubmed
Five
strains were allocated to DNA group 2 (
A. - pubmed
These four
strains represent two new DNA groups within the
A. - pubmed
A comparison of
tumor and normal tissue microvascular hematocrits and red cell fluxes in a
rat window chamber model . -
pubmed
This laboratory has previously used a window chamber model to measure red blood cell velocity in
mammary tumors and normal granulation tissues of the
F-344 rat . -
pubmed
packed cells were injected intravenously into
rats bearing an 8 to 10 day old R-3230
mammary carcinoma . -
pubmed
STUDY DESIGN : Forty - three
patients with symptoms related to
uterine enlargement of & lt ; 280 g who underwent total abdominal hysterectomy were compared to 73
patients with uteri weighing & gt ; or = 280 g. RESULTS : The mean age , parity , duration of disease and incident of past myomectomy were not different . -
pubmed
The effectiveness of a health education programme for prevention of
alcohol abuse and
tobacco smoking among adolescents was assessed by an intervention study with a non - randomized control group . -
pubmed
The health education programme included the prevention of
alcohol abuse in the first school year ( 1989 - 90 ) and the prevention of
tobacco smoking in the second year ( 1990 - 91 ) . -
pubmed
Case report : the MRI diagnosis of
bone marrow infarction in a
child with
leukaemia . -
pubmed
A double - blind , cross - over study was conducted with
hypertensive patients following a moderately salt - restricted diet . -
pubmed
After a 1 - month run - in period , 13
males and three females with mild to moderate
essential hypertension ( mean age 50 years ) complied with a salt - reduced diet . -
pubmed
It is concluded that moderate salt restriction seems not to adversely influence
insulin resistance or serum lipids in
hypertensive patients . -
pubmed
We report a
man who developed
selenium - deficient
myopathy during long - term parenteral nutrition . -
pubmed
Campylobacter jejuni and
Campylobacter coli are common causes of
gastroenteritis in
humans . -
pubmed
Antibodies to this peptide immunolocalized to the
zona pellucida of both
marmoset and
human ovarian sections and inhibited
human sperm -
zona binding by approximately 60 % in vitro . -
pubmed
In fact , the model will be a useful tool to investigate in detail , the pathological mechanisms of the
human inner ear disease associated with
Vogt - Koyanagi - Harada disease . -
pubmed
Staphylococcus hyicus is considered to be an etiological agent of
exudative epidermitis in young
pigs , but is frequently isolated from
chickens and
cows . -
pubmed
Spontaneous variability of cardiac output in ventilated
critically ill patients . -
pubmed
PATIENTS : A total of 22 hemodynamically stable acute
respiratory failure patients with a pulmonary artery catheter inserted for hemodynamic monitoring INTERVENTIONS : After being sedated ,
patients were randomized ultimately to receive pressure control ventilation first at setting A ( high positive end - expiratory pressure [ 15 cm
H2O ] with conventional I : E ratio [ 1:2 ] ) and then at setting B ( low positive end - expiratory pressure [ 5 cm
H2O ] with inverse I : E ratio [ 2:1 ] ) , or vice versa , and then at setting C ( low positive end - expiratory pressure [ 5 cm
H2O ] with conventional I : E ratio [ 1:2 ] ) . -
pubmed
CONCLUSIONS : In
critically ill sedated medical intensive care unit
patients with stable hemodynamics , the spontaneous variability of cardiac output over time was not significant . -
pubmed
METHODS : Seven hundred sixty - three
patients underwent an operation for
renal cell carcinoma between July 1989 and January 1999 . -
pubmed
Patients with
papillary renal cell carcinoma were at increased risk of developing
bladder cancer ( standardized incidence ratio [ SIR ] 6.5 , P = 0.038 ) . -
pubmed
CONCLUSIONS : There is an increased risk of subsequent
bladder and prostate cancer in
patients with
papillary renal cell carcinoma . -
pubmed
Patients were divided into patients with
depression /
mania onset before 40 and after 40 . -
pubmed
There were significant differences between the treatment and control groups , with regard to the number of
patients who still had
headache after 14 days ( 5 vs. 25 , respectively ; P=.00004 ) , the median length of time until complete disappearance of
headache ( 5 vs. 13 days , respectively ; P=.00000 ) , and the number of
patients who had repeat lumbar puncture ( 7 vs. 22 , respectively ; P=.002 ) . -
pubmed
These results indicate that a 2 - week course of
prednisolone was beneficial in relieving
headache in
patients with
eosinophilic meningitis . -
pubmed
[ Multilocular fixed drug reaction simulating
intertrigo in a
diabetic patient ] . -
pubmed
HISTORY AND CLINICAL FINDINGS : A 57 - year - old
man with
diabetes and
hypertension was treated with
amoxycillin ,
clarithromycin and
pantoprazole for a
gastric ulcer positive for
Helicobacter pylori . -
pubmed
The
patient was issued with an "
allergic to
penicillin " card . -
pubmed
CONCLUSION : Intertriginous changes during antibiotic treatment may not be due to
Candida intertrigo , which is fairly common , but to a prognostically much more important drug reaction . -
pubmed
There was a significant increase in
infections caused by
methicillin - resistant
S aureus ( P = .0001 ) and
vancomycin - resistant enterococci ( P = .04 ) over time . -
pubmed
Nausea and
vomiting continue to rank as important side effects for
cancer patients receiving chemotherapy . -
pubmed
Herpes simplex virus evolved to use the
human defense mechanisms to establish a lifelong
infection in neurons -- a review and hypothesis . -
pubmed
Based on these studies a hypothesis is presented suggesting that
HSV evolved to use the
human host defense systems (
pain signals , the immune system cells and sensory neurons ) to ensure its entry from the skin epithelium into the sensory neurons . -
pubmed
PATIENTS AND METHODS : In this open study , 38
patients ( 25
men and 13
women , age 19 - 68 ) with
chronic hepatitis B virus infection (
HBsAg ,
HBeAg and p - DNA
HBV positive ) were treated with
LAM ( 150 mg daily ) for 48 weeks . -
pubmed
All were negative for
HCV or
HDV coinfection and had no decompensated
liver disease . -
pubmed
The absence of side effects during
lamivudine therapy is of special importance especially in
patients with advanced
liver fibrosis . -
pubmed
Pharmacokinetics of
ropivacaine in
uremic and nonuremic
patients after axillary brachial plexus block . -
pubmed
Reports on the efficacy and pharmacokinetics of local anesthetics in
uremic patients have been controversial . -
pubmed
Our study involved 29
uremic and 28 nonuremic
patients . -
pubmed
Plasma clearance of
ropivacaine was smaller and the area under the concentration - time curve of
ropivacaine ,
3 - hydroxyropivacaine , and
PPX larger in the
uremic patients . -
pubmed
The plasma concentration of
PPX increased until 24 h in
uremic patients whose AAG concentrations were also larger throughout the study . -
pubmed
The free fraction of
ropivacaine in plasma was smaller in the
uremic group when measured 60 min and 12 h after the block , but the unbound concentration of
ropivacaine was larger in the
uremic group at 12 h. Enhanced absorption of
ropivacaine into circulation , increased binding to AAG , and probably reduced urinary excretion of the metabolites lead to larger total plasma concentrations of
ropivacaine and its main metabolites in
uremic patients . -
pubmed
Gene profiling and promoter reporter assays : novel tools for comparing the biological effects of botanical extracts on
human prostate cancer cells and understanding their mechanisms of action . -
pubmed
The use of botanical mixtures is commonplace in
patients with
prostate cancer , yet the majority of these products have not been rigorously tested in clinical trials . -
pubmed
Here we use PC - SPES , a combination of eight herbs that has been shown to be effective in clinical trials in
patients with
prostate cancer , as a model system to demonstrate ' proof of principle ' as to how gene expression profiling coupled with promoter assays can evaluate the effect of herbal cocktails on
human prostate cancer . -
pubmed
Our data suggest that gene expression profiles of
LNCaP human prostate cancer cells in response to PC - SPES are different from those found when
diethylstilbestrol (
DES ) , a synthetic
estrogen , is used , suggesting that the estrogenic moieties within PC - SPES do not drive this expression signature . -
pubmed
Influenza and
parainfluenza viruses as well as
RS virus affect frequently respiratory tract . -
pubmed
Viruses of viral
hepatitis B , C , D and
HIV ,
CMV ,
EBV may be the source of nosocomial
viral infections transmitted by blood ( transfusions ) . -
pubmed
[ Details concerning benign acute
histiocytopathy in
children ] . -
pubmed
In search of better outcome predictors for
patients following resection of colorectal
metastases . -
pubmed
Orotic acid - induced
fatty liver disease was investigated at the transcriptional and metabolic levels using microarrays and metabolic profiling in two
strains of
rats . -
pubmed
Importance of aggressive evaluation in
patients with
Staphylococcus aureus bacteremia . -
pubmed
Previously , we had shown that T cells accumulated in peribronchiolar and perivascular areas of lungs soon after intranasal
infection with
Streptococcus pneumoniae . -
pubmed
We investigated whether the " ornithophilous "
floral syndrome exhibited in an African sugarbush ,
Protea roupelliae ( Proteaceae ) , reflects ecological specialization for bird - pollination . -
pubmed
The predatory mite
Typhlodromus pyri ( Acari : Phytoseiidae ) causes feeding
scars on leaves and fruits of apple . -
pubmed
pyri females cause microscopic
scars on
apple leaves . -
pubmed
The present laboratory experiments were carried out to confirm the production of
scars on
apple leaves and to assess if females cause
scars on fruits as well . -
pubmed
Scar production on
apple leaves and/or fruits was investigated under various nutritional conditions : no food , pollen of
Scots pine (
Pinus sylvsestris L. ) only , nymphs of
P. - pubmed
Whether the
scars produced on leaves and fruits harm the quality of fruits or the yield of
apple can not be concluded from the present experiments . -
pubmed
Chronotherapy provides a means of individualizing treatment of
hypertension according to the circadian profile of blood pressure of each
patient . -
pubmed
Pseudoaneurysm of the femoral artery in a
HIV - infected man . -
pubmed
Rat
leprosy ; susceptibility of the black
mouse ( American race ) to the Stefamsky bacillus . -
pubmed
In this study , effect of
gadolinium , a synthetic Kupffer cell suppressant , on the
reperfusion injury was examined using a
canine partial liver transplantation model . -
pubmed
Tobacco use was more prevalent in the OR group ( 78.4 % versus 64.2 % ; P = .013 ) , and known
carotid artery disease was more prevalent in the EVAR group ( 20.0 % versus 6.9 % ; P = .003 ) . -
pubmed
To this aim , we have developed a
mouse model of
transverse aortic coarctation (
TAC ) between the two carotid arteries , which imposes acutely on the right brain hemisphere a dramatic increase in blood pressure . -
pubmed
Eradication of
Pseudomonas aeruginosa in
cystic fibrosis . -
pubmed
, like poultry and
cattle , reptiles have emerged as a significant source of
human salmonellae infections during the last years . -
pubmed
Neurologists need to recognize , diagnose , and treat
obstructive sleep apnea (
OSA ) in
patients with
stroke or
transient ischemic attack (
TIA ) . -
pubmed
Hypertension or
ischemic heart disease usually develops in untreated
patients with
OSA over time without particular worsening of
OSA . -
pubmed
Herein , we report a 48 - year - old
woman with a history of an incomplete excised nonchondroid
pulmonary hamartoma presenting as an indolent
tumor recurrence . -
pubmed
CASE REPORT : We report the case of a 43 - year - old
woman , who presented a chronic
autonomic failure , which had begun by symptomatic
orthostatic hypotension . -
pubmed
MATERIAL AND METHODS : Prospective evaluation of 21
patients ( 15
males , 6
females , 43 - 80 y ) with
diffuse lung diseases who underwent clinical work - up inclusive laboratory tests , lung - function tests and transbronchial biopsy . -
pubmed
CONCLUSION : Highfield MRI of the lung is feasible and performed slightly better compared to CT in the determination of activity in
patients with
interstitial lung diseases . -
pubmed
Severe
pulmonary hypertension occurred in the postoperative period in two
patients , and two
patients had
heart failure following a previous operation for
coarctation or interruption of the aorta . -
pubmed
The frequency of this allele in 305 blood donors , 90
patients with
systemic lupus erythematosus and 234 patients with the
systemic inflammatory response syndrome (
SIRS ) and/or
sepsis was 0.03 , 0.017 and 0.03 respectively . -
pubmed
PURPOSE : To assess the role of radiotherapy ( RT ) in
women with Stage IIIC
endometrial cancer . -
pubmed
METHODS AND MATERIALS : The 17 - registry Survival , Epidemiology , and End Results ( SEER ) database was searched for
patients with lymph node - positive
non - Stage IV epithelial endometrial cancer diagnosed and treated between 1988 and 1998 . -
pubmed
RESULTS : The therapy data revealed 611
women with Stage IIIC
endometrial cancer during this period . -
pubmed
Of the 611
patients , 293 had organ - confined Stage IIIC
endometrial cancer and 318
patients had Stage IIIC
endometrial cancer with direct extension of the primary
tumor . -
pubmed
In
patients with organ - confined Stage IIIC
endometrial cancer , the 5 - year OS rate was 50 % for NAT , 64 % for EBRT , and 67 % for EBRT / BT . -
pubmed
In
patients with Stage IIIC
endometrial cancer and direct
tumor extension , the 5 - year OS rate was 34 % for NAT , 47 % for EBRT , and 63 % for EBRT / BT . -
pubmed
CONCLUSION :
Women with Stage IIIC
endometrial cancer receiving adjuvant EBRT and EBRT / BT had improved OS compared with
patients receiving
NAT . -
pubmed
MicroRNA expression profile in granulocytes from
primary myelofibrosis patients . -
pubmed
OBJECTIVE : Expression profiling of microRNA ( miRNA ) was performed in granulocytes isolated from
patients with
primary myelofibrosis (
PMF ) , with the aim of identifying abnormally expressed miRNAs in comparison with normal subjects or
patients with
polycythemia vera (
PV ) or
essential thrombocythemia (
ET ) . -
pubmed
Chronic hepatitis B and C viruses (
HBV and
HCV ) are common problems in renal transplant patients . -
pubmed
Solid pseudopapillary neoplasm of the pancreas : distinct patterns of onset , diagnosis , and prognosis for male versus female
patients . -
pubmed
METHODS : The medical records of 34 consecutive
patients with
pancreatic solid pseudopapillary neoplasms between 1990 and 2006 were reviewed . -
pubmed
Tumor size tended to be smaller in
patients treated in more recent years . -
pubmed
Median hospital stay was 11 days , morbidity rate was 62 % , including 17
patients with grade A
pancreatic fistula , and there was no operative mortality . -
pubmed
Tumor recurred in 2
patients ( 6 % ) . -
pubmed
At the time of diagnosis , age was ( x + /- SD ) higher among male
patients ( 25 + /- 2 years vs 37 + /- 7 years ; P & lt;.05 ) with no difference in
tumor size . -
pubmed
UNLABELLED : The
obese patients adhere weakly to rehabilitation programs ; therefore the expected gains are often disappointing . -
pubmed
MATERIALS AND METHODS : Twenty
obese women were recruited . -
pubmed
To determine the preferred walk modality , 10
obese women performed a constant velocity walk and an intermittent walk ( with a similar duration and velocity ) on a treadmill . -
pubmed
CONCLUSION : The
obese patients preferred similarly the constant velocity walk and the intermittent walk , and a rehabilitation program based on an intermittent walk is effective in avoiding the
obesity aggravation . -
pubmed
This pooled risk estimate was marginally higher than the risk of a false - negative sentinel lymph node biopsy examination ( ie , 7%-8 % ) but marginally lower than the risk of
non - sentinel lymph node metastases in
patients with
micrometastases ( ie , approximately 20 % ) who are currently eligible for an axillary lymph node dissection . -
pubmed
Because 36 ( 64 % ) of the 56
patients with isolated
tumor cells in their sentinel lymph node also had non - sentinel lymph node macrometastases , those
patients with isolated
tumor cells in the sentinel lymph node without other indications for adjuvant systemic therapy might be candidates for axillary lymph node dissection . -
pubmed
In addition , supplementary administration of
vitamin K2 analogues to
HCC patients has led to reduce serum DCP levels . -
pubmed
In contrast , among reproductively nonphotoperiodic laboratory
strains of
rats and
mice , bulbectomy unmasks reproductive responses to photoperiod . -
pubmed
A group of 32 prepubertal
children with
idiopathic short stature ( ISS ) were included in the study . -
pubmed
PATIENTS AND METHODS : Epidemiologic data of
patients diagnosed with an
autoimmune bullous disease during this time period were registered and statistically evaluated . -
pubmed
RESULTS : During the study period , 41
patients with an
autoimmune bullous disease were diagnosed , including 27 with
bullous pemphigoid , 4 with
pemphigoid gestationis and
mucous membrane pemphigoid , 2 with
dermatitis herpetiformis and linear
IgA disease , and 1 with
epidermolysis bullosa acquisita and
pemphigus vulgaris , respectively . -
pubmed
Patients with
mucous membrane pemphigoid were found to have the highest mean age at disease onset ( 76 years ) followed by patients with
bullous pemphigoid ( 74 years ) . -
pubmed
PURPOSE : To compare the ability to delineate and detect patterns of
choroidal neovascularization ( CNV ) activity in
patients with exudative age - related
macular degeneration (
AMD ) after
ranibizumab treatment between time - domain optical coherence tomography ( TD - OCT ) and 4 different spectral - domain optical coherence tomography ( SD - OCT ) devices . -
pubmed
PARTICIPANTS : Sixty - one eyes of 58
patients with
exudative AMD after
ranibizumab treatment were included in this study . -
pubmed
CONCLUSIONS : SD - OCT is superior to TD - OCT in evaluating for CNV activity in
patients with wet
AMD after
ranibizumab injection . -
pubmed
This study investigated whether such image registration can also improve the quality of contrast - enhanced magnetic resonance angiography ( MRA ) in
patients with
peripheral arterial disease of the lower extremities . -
pubmed
In the spirit of Freud 's invitation to other investigators to elaborate on his " Notes Upon a Case of
Obsessional Neurosis " ( 1909 ) , the author offers additional and differing views on the case of the
Rat Man ( Dr. Ernst Langer ) . -
pubmed
METHODS : The
Tumor Registry of the Prince of Wales Cancer Centre was audited for
patients with an initial diagnosis of
squamous / nonsquamous cell NPC who had primary treatment with radiotherapy , and now presented for retreatment . -
pubmed
MP , in contrast to other smokeless
tobacco variants , seems to cause mucosal changes , which may transform into
oral cancer . -
pubmed
Melamine (
MEL ) has been involved in several food recalls after the discovery of severe
kidney damages in
children and
pets poisoned by
melamine - adulterated food . -
pubmed
The authors present the case of an 81 - year - old
patient with severe
aortic stenosis who experienced left ventricular embolization of an aortic bioprosthesis during transapical aortic valve implantation . -
pubmed
The intent of this study was to assess reproductive inhibition and
toxicity of
emamectin benzoate on
H. - pubmed
We further show that podocyte - specific knockdown and systemic short interfering RNA injection confers resistance to podocyte
injury in
mouse models of
nephrosis . -
pubmed
Parkinsonism can be
psychogenic , and
psychogenic parkinsonism is about 10 % of
psychogenic movement disorder patients . -
pubmed
Patients can present with any feature or combination of features of
organic Parkinson ' s disease . -
pubmed
Patients may have both
organic Parkinson ' s disease and
psychogenic parkinsonism , and this might be considered a psychologically induced aggravation of the
organic disorder . -
pubmed
PURPOSE : To evaluate the role of cryopexy or laser therapy versus observation for management of accidental
globe perforation during
strabismus surgery in an experimental
animal model . -
pubmed
CONCLUSIONS : Vision - threatening consequences of
globe perforation during
strabismus surgery were uncommon in this
rabbit model . -
pubmed
Mathematical models describing the transmission of
dengue viruses have focussed on the so - called antibody - dependent enhancement ( ADE ) effect and temporary cross - immunity trying to explain the irregular behavior of
dengue epidemics by analyzing available data . -
pubmed
We evaluated whether antiretroviral drugs affected the response to
pegylated interferon plus
ribavirin in patients co - infected with
HIV and hepatitis C virus (
HCV ) . -
pubmed
SCOPE : To evaluate the ability of
grape skin and seeds to protect endothelial progenitor cells ( EPC ) from oxidative stress induced by
hyperglycemia ( HG ) compared to red wine ( RW ) and prepare innovative pharmaceutical systems for the oral administration of red
grape extract allowing the overcoming of its poor intestinal absorption . -
pubmed
CONCLUSIONS :
Red grape components are a source of antioxidant compounds that ameliorate EPC viability and function , while preventing
endothelial dysfunction . -
pubmed
P301L
mice : possible implication for
neurodegenerative diseases . -
pubmed
P301L
mice suffer
upper airways defects related to
tauopathy within the Kolliker - Fuse nucleus that controls upper airways function . -
pubmed
P301L
mice triggered precocious
upper airways defects and
tauopathy in several brainstem nuclei , including the nucleus ambiguus that contains upper airways motor neurons and the Kolliker - Fuse . -
pubmed
Sirolimus in addition to a CNI is successful in reversing
inflammation in
LT recipients with
PTAH . -
pubmed
Suppression of plasma
estrogen levels by
letrozole and
anastrozole is related to
body mass index in
patients with
breast cancer . -
pubmed
CONCLUSION : The suppressed levels of plasma
estradiol and
estrone sulfate in postmenopausal
women with early
ER - positive breast cancer treated with the AIs
anastrozole and
letrozole are related to
BMI . -
pubmed
Study :
shingles vaccine safe for
patients on immune - suppressing drugs . -
pubmed
A 57 - year - old
man presented with
blurred vision associated with
photophobia and halos around lights . -
pubmed
BACKGROUND : Omalizumab has been shown to decrease the risk of hospitalization or ED visits in
patients with uncontrolled severe
allergic asthma compared with placebo . -
pubmed
METHODS : A cohort of adult
patients with uncontrolled severe
asthma despite optimal treatment with inhaled and oral
corticosteroids and a long - acting b 2 -agonist but no treatment with
omalizumab upon entry was assembled . -
pubmed
Systemic administration of
CART has been found to ameliorate dopaminergic neuronal loss and improve motor functions in a
mouse model of
PD . -
pubmed
Differences of aortic stiffness and aortic intima - media thickness according to the type of initial presentation in
patients with
ischemic stroke . -
pubmed
METHODS : A total of 500
patients with
acute stroke were divided into 2 groups : the
TIA group ( n = 230 , 62.4 + - 12 years , 144
males ) versus CI group ( n = 270 , 63.4 + - 11 years , 181
males ) . -
pubmed
RESULTS : After the
patient underwent a lung - sparing wedge resection of the pulmonary right upper lobe
metastasis and intraoperative brachytherapy with
( 131 ) Cs seeds to a total dose of 80 Gy , she remained disease free in the implanted area . -
pubmed
Fifty - nine at - risk
infants were enrolled , together with 1:1 matched healthy controls , and stratified by disease severity ( n=25 ,
HIE ; n=34 , non - HIE PA ) . -
pubmed
Gulls were reported as sources of fecal pollution in coastal environments and potential vectors of
human infections . -
pubmed
Minocycline modulates neuroprotective effect of
hesperidin against
quinolinic acid induced
Huntington ' s disease like symptoms in
rats : behavioral , biochemical , cellular and histological evidences . -
pubmed
In light of emerging role of
flavonoids in modulating oxidative stress and
neuro - inflammation , the study has been designed to explore the possible neuroprotective effect of
hesperidin and its combination with
minocycline ( microglial inhibitor ) , against
quinolinic acid ( QA ) induced
Huntington ' s disease (
HD ) like symptoms in
rats . -
pubmed
Taken altogether , the results of the present study suggest a possible interplay of microglial modulation and anti - oxidant effect in neuroprotective potential of
hesperidin against QA induced
HD like symptoms in
rats . -
pubmed
Heat - processed
Panax ginseng and
diabetic renal damage : active components and action mechanism . -
pubmed
Diabetic nephropathy is one of the serious complications in
patients with either
type 1 or 2 diabetes mellitus but current treatments remain unsatisfactory . -
pubmed
Results of clinical research studies demonstrate that
Panax ginseng can help adjust blood pressure and reduce blood
sugar and may be advantageous in the treatment of
tuberculosis and
kidney damage in people with
diabetes . -
pubmed
Coinfection of
WSSV and
IHHNV was also detected in crabs , blue and white shrimps . -
pubmed
Nonsteroidal anti - inflammatory drugs ( NSAIDs ) , including
acetylsalicylic acid (
ASA ) , improve
glucose metabolism in
diabetic subjects , although the underlying mechanisms remain unclear . -
pubmed
Pilot study of high - intensity focused ultrasound ablation as a bridging therapy for
hepatocellular carcinoma patients wait - listed for liver transplantation . -
pubmed
The objective of this study was to investigate the outcomes of high - intensity focused ultrasound ( HIFU ) ablation as a bridging therapy for
patients with
hepatocellular carcinoma (
HCC ) who had been wait - listed for deceased donor liver transplantation ( DDLT ) . -
pubmed
Patients in the BMT group had a significantly higher dropout rate ( P = 0.03 ) and significantly poorer liver function as reflected by higher Model for
End - Stage Liver Disease scores and higher Child - Pugh grading . -
pubmed
Clinically relevant
ascites was found in 5
patients in the HIFU group and 2
patients in the BMT group , but none was found in the TACE group ( P = 0.01 and P = 0.03 , respectively ) . -
pubmed
In conclusion , HIFU ablation was safe even for
HCC patients with
Child - Pugh C disease . -
pubmed
Intradural
spinal malignant peripheral nerve sheath tumors (
MPNST ) are extremely rare , with only 20 adult
patients reported to our knowledge , and only four primary
tumors arising from the cauda equina . -
pubmed
A 49 - year - old
man presented with
back pain ,
constipation , and
lower extremity weakness and was found to have a large intradural lesion involving the cauda equina . -
pubmed
The
patient underwent laminectomy for
tumor debulking and biopsy , as gross total resection was not possible due to envelopment of the cauda equina . -
pubmed
However , 6 weeks later , the
patient began having severe
headaches , and his
left temporal lobe lesion was found to have increased significantly in size , requiring craniotomy for palliative resection . -
pubmed
The authors report the first adult
patient with sporadic
spinal MPNST with craniospinal
metastasis to our knowledge . -
pubmed
We would like to report an extremely rare case of simultaneous bilateral knee
septic arthritis after bilateral knee intraarticular
steroid injection in a
rheumatoid arthritis patient . -
pubmed
Electroconvulsive therapy in a
patient with
catatonia and an
intracranial arachnoid cyst . -
pubmed
METHODS : Blood samples were collected from
patients with newly diagnosed
asthma ( 44 , 12
males , aged 33.75?8.94 ) , newly diagnosed
COPD ( 36 , 36
males , aged 68.03 + - 8.94 ) , and healthy control groups ( 23 , 9
males , aged 30.06 + - 7.50 ) . -
pubmed
Its role in the mechanisms of
COPD and
asthma in
human beings , as well as its therapeutic value in these diseases , need further investigation . -
pubmed
METHODS : We retrospectively examined a cohort of 152
DM patients . -
pubmed
RESULTS : Forty - three
patients ( 28 % ) had
cutaneous ulcers . -
pubmed
We aimed to visualise non - invasively the
tumour accumulation of these MoAb - targeted liposomes over time in tumour - bearing
mice using multispectral optoacoustic tomography ( MSOT ) . -
pubmed
MATERIALS AND METHODS :
Patients sustaining a
radial head fracture from 2002 - 2010 were screened for participation . -
pubmed
Twenty - five
patients with documented partial
articular radial head fractures were identified and completed the study . -
pubmed
Response to : comment on " Delayed
methotrexate excretion in infants and young
children with
primary central nervous system tumors and postoperative fluid collections " . -
pubmed
Some epidemiological and clinical studies indicate a protection of
omega-3 FA against
cardiovascular disease and a favourable effect on cardiovascular risk factors control in
adults . -
pubmed
Sulforaphane (
SFN ) is an
isothiocyanate found in
cruciferous vegetables with anti - inflammatory , anti - oxidant and anti -
cancer activities . -
pubmed
The prevalence of
anemia in
SCI patients with
PUs was found to be approximately 35 % . -
pubmed
Patients with
neurologic Wilson disease (
NWD ) may worsen on treatment , but there is no study evaluating the role of oxidative stress . -
pubmed
Fifty - one treatment - naive
NWD patients were subjected to detailed clinical evaluation . -
pubmed
The
patients were considered worsened if there was one or more grade deterioration in severity scale , > 10 % deterioration in BFM score or appearance of new
neurologic signs . -
pubmed
MATERIAL AND METHODS : A single centre study of 106 consecutive esophagectomies performed for
esophageal cancer by a minimally invasive approach in 79
patients was performed . -
pubmed
Transhiatal laparoscopic esophagectomy ( THLE ) was performed in 66
patients , transthoracic esophagectomy ( TTE ) in 13
patients , with histological findings of
squamous cell carcinoma in 28 and
adenocarcinoma in 51
patients . -
pubmed
Other serious complications included acute
myocardial infarction ( 1
patient ) and
necrosis of the gastroplasty ( 1
patient ) . -
pubmed
Anastomotic
dehiscence was observed in 8
patients , left recurrent laryngeal nerve
paralysis in 8
patients , intra - abdominal
abscesses in 2
patients , and
pleural empyema in 1 case . -
pubmed
The clinical features , imaging findings , histopatholigical examination , and management in 3 case reports of
children with misdiagnosed
retinoblastoma are presented . -
pubmed
Mean
patient age was 66.6 + - 1.1 years , 74.2 % were
men , and 48.3 % had
diabetes mellitus . -
pubmed
Neutrophils have been shown to efficiently kill
Cryptococcus neoformans , a causative agent of
meningoencephalitis . -
pubmed
METHODS : Fifty
patients with
malignant obstructive jaundice treated from September 2010 to February 2013 in Yantai Yuhuangding Hospital were included in this study . -
pubmed
CONCLUSION :
( 125 ) I seeds combined with biliary stent implantation can inhibit the proliferation of vascular endothelial cells and the growth of
tumor effectively , and can prolong the biliary stent patency time and the survival time obviously for
patients with
malignant obstructive jaundice , therefore , is a safe and effective treatment in this
malignancy . -
pubmed
The role of the addition of ovarian suppression to
tamoxifen in young
women with
hormone - sensitive breast cancer who remain premenopausal or regain menstruation after chemotherapy ( ASTRRA ): study protocol for a randomized controlled trial and progress . -
pubmed
BACKGROUND : Ovarian function suppression ( OFS ) has been shown to be effective as adjuvant endocrine therapy in premenopausal
women with
hormone receptor - positive breast cancer . -
pubmed
In 2008 , the Korean
Breast Cancer Society Study Group initiated the ASTRRA randomized phase III trial to evaluate the efficacy of OFS in addition to standard
tamoxifen treatment in
hormone receptor - positive breast cancer patients who remain or regain premenopausal status after chemotherapy . -
pubmed
METHOD : Thirty
patients suffering from
MDD participated in the study . -
pubmed
In
beta - thalassemic mice transplanted with beta - thalassemic HSCs transduced with the gamma - globin / NA10HD vector , the number of
fetal hemoglobin ( HbF )- expressing cells was significantly increased after 3 months , leading to resolution of the
anemia . -
pubmed
The combined treatment with weekly
paclitaxel and
PNC-27 was tested in an intraperitoneal
mouse model of
ovarian cancer (
ID8 ) . -
pubmed
The initial
neurologic signs of 212
individuals exposed to gradual ( N=114 ) and rapid ( N=98 ) onset + Gz acceleration stress , inducing the ischemic LOC phase in 83.3 + -18.6s and 8.89 + -1.52s ; p<0.001 respectively , were determined . -
pubmed
Effects of the " plate model " as part of dietary intervention on modification of selected cardiometabolic risk factors in
post - myocardial infarction patients : study protocol for a randomized controlled trial . -
pubmed
Healthy eating as a cost - effective approach to risk reduction in
post - myocardial infarction patients is proven to be beneficial , and the " plate model " is one of the practical methods to achieve this objective . -
pubmed
The caustic (
NaOH ) content in
bauxite residue leads to
human health risks , like dermal problems and
irritation to eyes . -
pubmed
Here , we determine the frequency of these mutations and define the genotype - phenotype characteristics in a large cohort of
patients diagnosed clinically with
PAH . -
pubmed
CASE PRESENTATION : We reported a 52 - year - old
woman who complained of
dyspnea for 2 months and
dry cough for 10 days . -
pubmed
Surgery remains the preferred treatment for
patients with primary
cardiac angiosarcoma . -
pubmed
CONCLUSION : Elevated NLR predicts worse outcomes in
patients with
HNSCC . -
pubmed
MATERIALS AND METHODS : From 2004 to 2012 , 75
patients underwent TSA for primary
osteoarthritis with minimum 5 - year follow - up . -
pubmed
RESULTS : Qualitative evaluation of
cyst formation resulted in the following distribution : no
cysts in 8
patients ( 11 % ) , small
cyst formation in 27 ( 36 % ) , medium
cysts in 19 ( 25 % ) , and large
cysts in 21 patients ( 28 % ; kappa = 0.605 ) . -
pubmed
All revised
patients were in the groups with medium or large
cysts . -
pubmed
Treatment Based on
Cinacalcet Reduces Oxidative Stress in Hemodialysis
Patients with
Secondary Hyperparathyroidism . -
pubmed
BACKGROUND / AIMS : Oxidative stress is one of the leading factors contributing to increased mortality in
patients with
chronic kidney disease (
CKD ) and
secondary hyperparathyroidism (
sHPT ) . -
pubmed
Cinacalcet is now commonly used in the treatment of
sHPT in
patients with
CKD . -
pubmed
CONCLUSIONS : ( 1 ) Six - month treatment based on
cinacalcet seems to reduce oxidative stress markers in maintenance hemodialysis
patients with
sHPT . -
pubmed
RESULTS : Fifty - one articles met inclusion criteria , resulting in 6,227
patients who underwent mesh repair of a
ventral hernia . -
pubmed
Changes in cell differentiation and proliferation lead to production of abzymes in
EAE mice treated with DNA - Histone complexes . -
pubmed
Experimental
autoimmune encephalomyelitis (
EAE)-prone C57BL/6
mice are used as a model of
human multiple sclerosis . -
pubmed
Adult
Zebrafish Injury Models to Study the Effects of
Prednisolone in Regenerating Bone Tissue . -
pubmed
Furthermore ,
zebrafish are able to heal bone rapidly after trepanation of the skull , and repair
fractures that can be easily introduced into
zebrafish bony fin rays . -
pubmed
We provide a workflow on how to prepare for immunosuppressive treatment in adult
zebrafish , illustrate how to perform fin amputation , trepanation of calvarial bones , and fin
fractures , and describe how the use of glucocorticoids affects both bone forming osteoblasts and cells of the monocyte / macrophage lineage as part of innate immunity in bone tissue . -
pubmed
Renal carcinoma presents a rapid progression in
patients with high
metastasis with no effective therapeutic strategy . -
pubmed
Processing
sweet corn (
Zea mays ) growers in New York are more concerned about the cost effectiveness of fungicide use against foliar
fungal diseases ( common rust and Northern
corn leaf blight ) and less about whether such sprays will reduce disease intensity . -
pubmed
Predicting
stroke in
patients without
atrial fibrillation . -
pubmed
BACKGROUND : Only few studies in selected cohorts have examined whether the CHA2 DS2 -VASc score can predict the risk of
atrial fibrillation and
thromboembolic events in
patients without
atrial fibrillation . -
pubmed
We excluded
patients with
atrial fibrillation , anticoagulant therapy and follow - up & lt;30 days . -
pubmed
Patients with a CHA2 DS2 -VASc score of 3 had a rate of
ischaemic stroke /
transient ischaemic attack /
systemic embolism of 1.30 per 100 person - years . -
pubmed
CONCLUSIONS : Among
patients undergoing coronary angiography , the CHA2 DS2 -VASc score predicted a future diagnosis of
atrial fibrillation and the composite risk of
ischaemic stroke ,
transient ischaemic attack or
systemic embolism in
patients without
atrial fibrillation . -
pubmed
A CHA2 DS2 -VASc score of 3 was associated with a risk that would justify prophylactic oral anticoagulation treatment in a
patient with
atrial fibrillation . -
pubmed
Rangelia vitalii is the protozoan responsible for a
febrile tick - borne disease known as " Nambiuvu " or "
bleeding plague . " -
pubmed
Children and their parents were enrolled prior to surgery and completed baseline psychological instruments assessing parental
anxiety ( STAI ) , parental coping style ( MBSS ) , child temperament ( EAS ) and parental medication administration attitude questionnaire ( MAQ ) . -
pubmed
Postoperatively , parents and children completed at - home
pain severity ratings ( Faces
Pain Scale - Revised ,
children ; Numeric Rating Scale ,
parents ) on postoperative recovery days 1 , 2 , and 3 , reflecting an overall
pain level for the past 24 h. Parents also completed a log of analgesic administration . -
pubmed
CONCLUSIONS : Since parents overestimate their child 's
postoperative pain and may administer more analgesics to their child , it is essential to develop a standardized method of child
pain assessment and a tailored recommended postoperative analgesic regimen amongst medical providers for
children undergoing T&A. -
pubmed
Simple Cholecystectomy Is Adequate for
Patients With T1b Gallbladder
Adenocarcinoma & lt ; 1 cm in Diameter . -
pubmed
This study attempts to better define the current criteria for local treatment of T1b
GBA , by examining the relationship between lymph node ( LN )
metastasis and
tumor size in such
patients . -
pubmed
Patients and methods : Clinical data from
patients with T1b
GBA receiving curative surgical treatment between 2004 and 2015 were collected from the Surveillance , Epidemiology , and End Results ( SEER ) database . -
pubmed
Among them , 23
patients had
tumors & lt;1 cm in diameter , none of which had LN
metastasis ; 104
patients had
tumors & gt;=1 cm , 15 of which had positive LNs . -
pubmed
A clinical benefit was observed in T1b
GBA patients with a
tumor size & gt;=1 cm receiving EC vs. those receiving SC ( P = 0.012 ) . -
pubmed
Continuous contact of air pollutants on
human skin has produced early ageing and led to roughness ,
dryness , poor elasticity , increased wrinkling and irregular pigmentation of the skin . -
pubmed
The skin melanin ,
erythema , moisture and elasticity values of both the right and left cheeks of the
volunteers were measured at baseline visits : 15 , 30 , 45 , 60 , 75 and 90 days of time intervals . -
pubmed
CONCLUSION : Treatment with
crisaborole 2 % ointment was well - tolerated and led to clinical improvement in
subjects with
intertriginous , anogenital , or facial psoriasis . -
pubmed
OBJECTIVE : The aim of this study was to delineate the kinetics of
coagulation dysregulation after
injury in
children . -
pubmed
SUMMARY BACKGROUND DATA :
Trauma - induced
coagulopathy is common and portends poor outcomes in severely - injured
children . -
pubmed
METHODS : Records of severely injured
children age & lt;18 years with rapid thromboelastography ( TEG ) on arrival and documented time of
injury were queried . -
pubmed
RESULTS : A total of 285
patients were included : median ( interquartile range ) age = 11 ( 6 - 15 ) ,
injury severity score = 17 ( 10 - 25 ) , 75 % blunt mechanism , 32 % severe
TBI , 11 % mortality , 28 %
functional disability . -
pubmed
Patients with
TBI had significant increase in incidence of fibrinolysis SD beyond 1 hour after
injury as compared to non -
TBI patients . -
pubmed
Effect of
Empagliflozin on Cardiac Function , Adiposity , and Diffuse
Fibrosis in
Patients with
Type 2 Diabetes Mellitus . -
pubmed
This prospective study enrolled 35
patients ( 48.6 %
men , age 63.5 + - 9.7 years ) with
type 2 diabetes mellitus (
T2DM ) from June 1 , 2017 , to November 31 , 2018 . -
pubmed
This study demonstrated that 6 months of
empagliflozin treatment did not significantly improve the LV function , structure , adiposity , and diffuse
fibrosis in
patients with
T2DM . -
pubmed
The Proteolytic Fraction From
Vasconcellea cundinamarcensis Latex Displays Anti - Inflammatory Effect in A
Mouse Model of Acute TNBS - Induced
Colitis . -
pubmed
The proteolytic fraction ( P1G10 ) from
Vasconcellea cundinamarcensis , displays gastric protective and healing activities in different
skin lesions in
mice and
human . -
pubmed
Based on these data , we assessed its anti - inflammatory activity in
murine colitis model , induced by
2,4,6 - trinitrobenzenesulfonic acid (
TNBS ) adopted by its physiopathological similarity with
human colitis . -
pubmed
MATERIALS AND METHODS : This is a prospective interventional trial on 27 naive
patients with
BPH and
lower urinary tract symptoms (
LUTS ) . -
pubmed
PV reduction in
patients without
metabolic syndrome ( DeltaPVV1nMetS -4.7 mL,95%CI -7.3;-2.0 ) was greater than in affected
patients ( DeltaPVV1MetS 1.7 mL,95%CI -2.69;6.1)(p=0.017,Relative RiskMetS = 6 ) . -
pubmed
Patients with moderate - severe
LUTS and without
MetS seem to benefit more from this treatment . -
pubmed
CONCLUSION :
PEMF reduces PV and improves
LUTS in a relative short time , in
BPH patients . -
pubmed
These benefits seem greater in those
patients with moderate - severe
LUTS but without
MetS. -
pubmed
Aripiprazole in
youth with
intellectual disabilities : A retrospective chart study . -
pubmed
A retrospective chart study of
patients on open - label
aripiprazole treatment was conducted in the Netherlands to add to the knowledge of
aripiprazole in
children and young adults with mild and borderline
intellectual disabilities ( IDs ) . -
pubmed
For 83 % of the
patients ,
disruptive behavior was the main target symptom . -
pubmed
Mild adverse events were observed in 53 % of the
patients of which
fatigue and
weight gain were the most common . -
pubmed
In 53
children and young
adults with mild and borderline
IDs ,
aripiprazole was effective in both the short and the long term . -
pubmed
On average , presentation is about 20 years after radiotherapy , and
patients commonly present with
headaches , complex
seizures , and
stroke - like symptoms . -
pubmed
CASE REPORT We present one such case of a 28 - year - old
man who presented to our Emergency Department with a gradually progressive severe
headache and right - sided
weakness developing over a few hours . -
pubmed
Even in very severe cases of
RSV infection treatment modalities like
NO , HFOV and ECMO can be used successfully . -
pubmed
Duodenal - Jejunal Exclusion Surgery Improves
Type 2 Diabetes in a
Rat Model Through Regulation of Early
Glucose Metabolism . -
pubmed
OBJECTIVES : Metabolic surgery has been proven to be widely effective for the control of
glucose and weight in
patients with
type 2 diabetes and
obesity . -
pubmed
This study aimed to measure the effects of duodenal - jejunal exclusion on glycometabolism in nonobese
rats with
type 2 diabetes and to investigate its mechanisms . -
pubmed
CONCLUSIONS : Duodenal - jejunal exclusion surgery is an effective procedure for improving
glucose metabolism independent of weight loss in nonobese
rats with
diabetes . -
pubmed
Healthcare professionals have been infected with the virulent
severe acute respiratory syndrome coronavirus-2 (
SARS ) , which spreads by close contact and aerosols . -
pubmed
Prenatally androgenized ( PNA )
mice mimic neuroendocrine aspects of
polycystic ovary syndrome (
PCOS ) . -
pubmed
Therefore , the risk of
human colonization /
infection with
MRSA linked to the handling of raw milk or consumption of contaminated dairy products should not be ruled out . -
pubmed
Children born with
HHcy have
musculoskeletal abnormalities /
growth retardation . -
pubmed
Collectively , results imply that
individuals with mild / moderate
HHcy seem more prone to skeletal
muscle injury and its dysfunction . -
pubmed
The effect of bio / organic fertilizers on the
phytotoxicity of
sulfadiazine to
Echium amoenum in a calcareous soil . -
pubmed
To tackle this question , we established an experimental platform for
human diffuse
gastric cancer that enables accurate modeling of histological subtypes . -
pubmed
METHODS : Seven
patient - derived diffuse
gastric cancer organoid lines were established characterized by histopathological analysis , in situ hybridization and gene expression analysis . -
pubmed
GFP - labeled
gastric cancer organoids were xenotransplanted into immune - deficient
mice for in vivo assessment . -
pubmed
The association between Wnt target gene expression and histological subtypes was confirmed in three
patient - derived
gastric cancer tissues . -
pubmed
Our results decoded how genetic mutations and the
tumor environment shape pathohistological and biological phenotypes in
human diffuse
gastric cancers . -
pubmed
METHODS : Retinal thickness was measured using spectral - domain optical coherence tomography in a 78 - week randomized placebo - controlled trial of
verubecestat in 1,785
patients with mild - to - moderate
AD . -
pubmed
BACKGROUND : Personalized ENCALS survival prediction model reliably estimates the personalized prognosis of
patients with
amyotrophic lateral sclerosis . -
pubmed
CASE REPORT : A 43 - year - old
woman presented with symptoms of acute
abdominal pain . -
pubmed
Plant growth - promoting experiments with the use of Waito - C
rice seedlings show that some of the fungal
strains could encourage a more efficient growth than others . -
pubmed
Impact of
diabetes status in
patients suffering of non - valvular
atrial fibrillation requiring anticoagulation have been analysed previously and risk / benefit balance of NOACs have been confirmed in these patients . -
pubmed
The usual culprits -
yeasts belonging to the genera Malassezia and
Candida - are commensal species in the skin that can cause
opportunistic infections . -
pubmed
CONCLUSIONS : Cell surface
GAGs appear to play a role in the adhesion of
C albicans and Malasezzia species to keratinocytes . -
pubmed
Clindamycin - induced
enterocolitis in
hamsters as a model of
pseudomembranous colitis in patients . -
pubmed
Stools from a patient with
antibiotic - associated colitis and cecal contents from a
hamster with
clindamycin - induced
enterocolitis were compared in a
cytotoxicity assay to determine common properties . -
pubmed
These results indicate that
clindamycin - induced
enterocolitis in
hamsters is a model of
human disease and implicate toxin - producing clostridia as responsible agents . -
pubmed
Report of a case of
bacterial sepsis caused by a naturally occurring variant form of
Staphylococcus aureus . -
pubmed
In a 6 - week open study in 24
patients with
rheumatoid arthritis ,
tolmetin was shown to have analgesic and anti - inflammatory activity at daily doses in excess of 1200 mg per day and produced statistically significant reductions in overall joint
pain , walking time and articular index . -
pubmed
The drug was well tolerated , but 2
patients were withdrawn because of persistent
indigestion and 1 because of an
urticarial type rash . -
pubmed
Mothers were fed a diet containing 2 %
lead acetate acording to the Pentschew - Garro model for inducing lead
encephalopathy in young
rats . -
pubmed
Congenital malformations of the mitral valve in
children . -
pubmed
Associated lesions ( ventricular or
atrial septal defects ,
coarctation , or
aortic valve stenosis ) were present in 31
patients ( 65 per cent ) and were corrected during the same operation . -
pubmed
Minimal or moderate regurgitation and
cardiomegaly persisted in the majority of the
patients . -
pubmed
[ Early recognition of the
child with
behavior disorders ] . -
pubmed
However , the magnitude of the changes in blood pressure was less in portal
hypertensive rats . -
pubmed
Monitoring of
patients with
rheumatoid arthritis in longterm administration of
D - penicillamine . -
pubmed
Acute
infection with lymphocytic choriomeningitis virus causes a severe immune suppression in immunocompetent
mice by triggering a T cell - mediated immunopathology , probably directed against infected macrophages and dendritic cells . -
pubmed
Osteoporosis is a frequent complication of
rheumatoid arthritis (
RA ) , especially in postmenopausal
women , and may involve both juxtaarticular and generalized
bone loss . -
pubmed
To examine the effect of exogenous
estrogens and endogenous
androgens on
bone loss in
RA we determined rates of
bone loss by serial bone density measurement for up to 4 years in 38 postmenopausal
women with
RA . -
pubmed
To remove regionally recurrent
cancer of the rectum completely , more radical extensive resections were attempted than the conventional ones in 35
patients . -
pubmed
[ The therapy of the
metritis ,
mastitis , agalactia ( MMA ) complex of
swine ] . -
pubmed
The severity of excitotoxic
brain injury is dependent on brain temperature in immature
rat . -
pubmed
The effect of brain temperature on the severity of excitotoxic
brain injury was evaluated in perinatal
rats . -
pubmed
Animals were sacrificed 5 days later and the severity of
brain injury was assessed quantitatively by comparison of the weights of the injected and contralateral cerebral hemispheres . -
pubmed
Injection of
NMDA consistently produced extensive unilateral
brain injury in
rats maintained at normothermia ( 36 degrees C ambient temperature ; 29 + /- 1.8 % reduction in the weight of the injected hemisphere ) . -
pubmed
Two
patients , a 64 - year - old
woman and a 40 - year - old
man , developed a
lupuslike syndrome due to
lovastatin therapy , confirmed by signs , symptoms , and positive fluorescent antinuclear antibodies are herein published . -
pubmed
Rotavirus - specific cytotoxic T lymphocytes passively protect against
gastroenteritis in suckling
mice . -
pubmed
Rotavirus - specific cytotoxic T lymphocytes may be important in either amelioration of
acute infection or protection against reinfection . -
pubmed
Strain gauge plethysmography in the assessment of
venous reflux after subfascial closure of perforating veins : a prospective study of twenty
patients . -
pubmed
In 10
patients ( 50 % ) the valves of the deep veins were incompetent as verified by Doppler ultrasonography , and
deep vein thrombosis had previously been diagnosed in seven
patients . -
pubmed
In two of four
patients with fair subjective results the arterial flow was pathologically high , which probably implies the presence of microscopic
arteriovenous fistulas . -
pubmed
Although the question of booster dose for residual primary lesion arises in only 5 % of
nasopharyngeal carcinoma patients receiving radiotherapy , it poses a difficult problem for clinicians and should be followed . -
pubmed
Three out of six men infected with
HIV had had previously
syphilis . -
pubmed
The application of these techniques in two
murine tumour systems provides evidence that such
hypoxia exists and reduces the effectiveness of single doses of radiation . -
pubmed
Classical endoscopic vesical neck suspension was performed in 93
patients with cure of
incontinence in 89 ( 95.7 % ) . -
pubmed
The following topics are covered in this brief review on the environmental and occupational toxicology of
chromium : occurrence , production and uses of
chromium and
chromium compounds ; experimental toxicology ;
chromium toxicity for
man ; hygienic and ecologic aspects of
chromium contamination of the environment . -
pubmed
Esotropic children with
amblyopia : effects of patching on acuity . -
pubmed
The rates of improvement of acuity in response to full - time occlusion therapy of 30 esotropic
patients with
amblyopia were determined . -
pubmed
The age - related changes in responsiveness to patching were modeled nonlinearly to provide quantitative guidelines for management of occlusion therapy of esotropic
children with
amblyopia . -
pubmed
Suppression of exercise - induced
angina by
magnesium sulfate in
patients with
variant angina . -
pubmed
The effects of intravenous
magnesium on exercise - induced
angina were examined in 15
patients with
variant angina and in 13
patients with stable
effort angina and were compared with those of placebo . -
pubmed
Exercise - induced
angina associated with transient ST segment elevation occurred in 11
patients with
variant angina receiving placebo and in only 2 of these
patients receiving
magnesium ( p less than 0.005 ) . -
pubmed
On the other hand , exercise - induced
angina was not suppressed by
magnesium in any
patient with stable
effort angina . -
pubmed
The size of the perfusion defect as measured by
thallium-201 scintigraphy was significantly less in
patients with
variant angina receiving
magnesium than that in those receiving placebo ( p less than 0.001 ) , whereas it was not significantly different in
patients with stable effort
angina receiving placebo versus
magnesium . -
pubmed
In conclusion , exercise - induced
angina is suppressed by intravenous
magnesium in
patients with
variant angina but not in
patients with stable
effort angina . -
pubmed
This beneficial effect of
magnesium in
patients with
variant angina is most likely due to improvement of regional myocardial blood flow by suppression of
coronary artery spasm . -
pubmed
Mice were treated at the non - lethal dose of 100 mg kg-1 which inhibited
tumour growth almost completely . -
pubmed
In non - tumour bearing
mice we studied the time course of the reversal of the haematological
toxicity of
5FU . -
pubmed
[
Metastatic calcinosis in
patients on long - term dialysis ] . -
pubmed
A 14 year - old
boy with
coeliac disease and poorly treated
diabetes mellitus and
pulmonary tuberculosis due to
INH resistant
BK presented with a permanent
malabsorption of
rifampicin . -
pubmed
The size of the foramen magnum in
patients with
achondroplasia was small at all ages , particularly in those with serious neurologic problems . -
pubmed
The data suggest that measurement of the foramen magnum may identify achondroplastic
individuals at high risk of developing
neurologic complications . -
pubmed
Onset and development of
anaemia in
sheep experimentally infected with
Schistosoma mattheei -- ferrokinetic studies . -
pubmed
[ Evolution of the ultrastructure of the ovoendometrial connections under the influence of
estrogen in the
rat during experimental
retardation of nidation ] . -
pubmed
Acetylsalicylic acid or
indomethacin were found to suppress the aggregation activity of
thyrotoxicosis patients ' platelets . -
pubmed
Pasteurella multocida septic arthritis . -
pubmed
"
Non - accidental injury " and wild
parsnips . -
pubmed
Facultative
Pasteurella ophthalmitis in
Hooded Lister rats . -
pubmed
Hooded Lister rats were found to exhibit symptoms of
Mycoplasma pulmonis infection . -
pubmed
During the course of this chronic
respiratory disease they developed
ophthalmia and
conjunctivitis which proved to be an opportunist
infection with
Pasteurella multocida . -
pubmed
The severity of disease varied in individual
rats , newborn
rats entirely escaping
infection . -
pubmed
The altered apoprotein composition suggested that the
hyperlipoproteinemia associated with
cholesterol feeding in the
rat is due to an inadequate rate of removal of lipoproteins of intestinal origin , and that this is greatly exacerbated by
diabetes . -
pubmed
This should improve the safety of the use of controlled
hypotension and may well identify those
patients requiring more aggressive postoperative treatment . -
pubmed
In the past eight years we have treated 22
patients suffering from acute
infection of the knee joint and the
talo - crural joint . -
pubmed
A
hypertensive episode precipitated by
avocados in a
patient on
tranylcypromine is described . -
pubmed
This is the first documented case of
avocado induced
hypertensive crisis . -
pubmed
Extraocular application of
mitomycin C in a
rabbit model :
cytotoxic effects on the ciliary body and epithelium . -
pubmed
Thirteen
patients with severe
aortic stenosis and
left ventricular dysfunction ( ejection fraction & lt ; 0.50 , Group A ) received echocardiographic evaluation before , and early and late after isolated aortic valve replacement . -
pubmed
The results were compared with those of 11
aortic stenosis patients without
left ventricular dysfunction ( Group B ) . -
pubmed
It is concluded from the above results , that LV contraction in
aortic stenosis patients with preoperative
left ventricular dysfunction improved during the late postoperative period . -
pubmed
Alterations in colonic smooth muscle function in
cats with
idiopathic megacolon . -
pubmed
OBJECTIVE : To determine whether
colonic smooth muscle dysfunction is involved in the pathogenesis of
idiopathic megacolon in
cats . -
pubmed
ANIMALS : Colon from healthy
cats and
cats with
idiopathic megacolon . -
pubmed
CONCLUSIONS :
Idiopathic megacolon is a generalized dysfunction of colonic smooth muscle in
cats . -
pubmed
The
patient is currently well with a stable engraftment 6 months following allogeneic PBSC transfusion , with no signs of acute of chronic
GVHD . -
pubmed
Most
human organ - specific
autoimmune diseases such as
Hashimoto ' s thyroiditis (
HT ) are considered to be Th1 mediated , and a quantitative dominance of Th1 cells in thyroid infiltrates from both
Graves ' disease (
GD ) and
HT affected glands has been reported . -
pubmed
Results showed a reduction of self - reported
tobacco withdrawal symptoms using the
nicotine patch alone . -
pubmed
BACKGROUND : As many as 20 % of
individuals with the clinical diagnosis of
Parkinson ' s disease (
PD ) do not have the characteristic neuropathologic features of
PD at post mortem . -
pubmed
METHODS : We have estimated regional brain
iron content in a
patient with probable
SND , using a novel imaging method developed in our laboratory , and have compared the results in this patient to those which we have previously reported in
patients with
PD and in age - matched controls . -
pubmed
RESULTS : We observed that putamenal
iron content was increased in our
SND patient , beyond the 95 % confidence limit for inclusion in the
PD group , even when considering clinical severity . -
pubmed
CONCLUSIONS : The demonstration of increased putamenal
iron content may be a useful adjunctive investigative procedure in
patients with suspected
SND . -
pubmed
None of the
patients undergoing partial middle turbinectomy for
nasal obstruction developed frontal
sinusitis postoperatively . -
pubmed
Maedi - visna virus and
caprine arthritis - encephalitis virus : distinct species or quasispecies and its implications for laboratory diagnosis . -
pubmed
The lentiviruses responsible for causing
maedi -
visna or ovine progressive
pneumonia in
sheep and
caprine arthritis - encephalitis in
goats have long been considered distinct , albeit related , viral species . -
pubmed
METHODS : The present longitudinal study investigated a population based group of borderline
hypertensive men ( BHT , n = 66 ,
diastolic blood pressure ( BP ) 85 - 94 mm Hg ) . -
pubmed
Characterization of
mouse parvovirus infection among BALB / c
mice from an enzootically infected colony . -
pubmed
A correlation ( r = 0.250 , P = 0.0089 ) was evident between the presence of
HPV 16 and occurrence of invasive
cancer . -
pubmed
Linomide is a synthetic immunomodulator that has been shown to protect
animals against a wide range of spontaneously developing or induced
autoimmune diseases . -
pubmed
We have previously reported that
Linomide blocks both the clinical and the histopathological manifestations of experimental
autoimmune encephalomyelitis (
EAE ) in various
animal models . -
pubmed
It had a marked therapeutic effect in the treatment of
staphylococcal sepsis in
albino mice and was low toxic . -
pubmed
HMA was also used to simplify the identification of mixed
infection with two
HCV genotypes . -
pubmed
Septic complications were responsible for early
death and disease
recurrence for late
patient loss . -
pubmed
Radiofrequency catheter ablation has established itself as a first line therapy for the curative treatment of many
patients with
supraventricular or atrioventricular tachycardias and also for selected types of
ventricular tachycardia . -
pubmed
In
patients undergoing radiofrequency ablation procedures , radiation exposure carries a small but measurable risk of
malignancy and
hereditary disorders . -
pubmed
In
patients undergoing ablation of
ventricular tachycardia , a higher incidence of total procedure related complications between 5 - 7 % and severe complications ( 3 - 4 % ) may be expected . -
pubmed
Follow - up information on 10
patients ( range : 6 to 77 months ; median : 18 months ) showed no
recurrence . -
pubmed
A 26 - year - old
man who underwent aortic valve replacement for
aortic regurgitation due to
Takayasu ' s arteritis 2 years earlier experienced left
amaurosis persisting for some minutes . -
pubmed
Following administration of a
calcium antagonist , the
patient 's
amaurosis subsided and brain bloodstream scintigraphy showed no abnormalities . -
pubmed
PURPOSE : To evaluate the diagnostic accuracy of contrast - enhanced magnetic resonance angiography ( CE - MRA ) MoBI - trak of peripheral vessels in
patients with
peripheral vascular disease who were candidates for digital subtraction angiography ( DSA ) . -
pubmed
RESULTS : The presence of both
galactitol and
galactonate was identified in RBC of 15
galactosemic and 13 normal
subjects by their mass spectra and chromatographic comparisons with both unlabeled and
13C labeled standards . -
pubmed
CONCLUSION : The determination of these compounds in RBC along with
galactose-1 - phosphate (
gal-1 - P ) in the same procedure provides the potential for their use in better monitoring of diet therapy in
galactosemic patients . -
pubmed
CONCLUSION :
Tuberculosis should be entertained as a possible diagnosis in
patients with nonspecific
laryngeal disease . -
pubmed
Nonetheless , by the description of aberrant induction and/or maintenance of the mammary rudiments in a variety of inbred
mouse strains and mutants , we have accumulated data demonstrating that the mammary rudiments develop independently of each other at these positions . -
pubmed
Plasticity in the tonotopic organization of the medial geniculate body in adult
cats following restricted unilateral
cochlear lesions . -
pubmed
To investigate subcortical contributions to cortical reorganization , the frequency organization of the ventral nucleus of the medial geniculate body ( MGv ) in six normal adult
cats and in eight
cats with restricted unilateral
cochlear lesions was investigated using multiunit electrophysiological recording techniques . -
pubmed
The tonotopic organization of MGv in the lesioned
animals , with severe mid - to -
high frequency hearing losses , was investigated 40 - 186 days following the lesioning procedure . -
pubmed
Intensification of therapy for
children with lower - risk
acute lymphoblastic leukemia : long - term follow - up of
patients treated on
Children 's Cancer Group Trial 1881 . -
pubmed
PURPOSE : From December 1988 through December 1992 , the
Children 's Cancer Group ( CCG ) conducted a randomized trial ( CCG-1881 ) designed to evaluate the impact of adding a single delayed intensification phase of therapy to standard therapy for
patients with newly diagnosed low - risk
acute lymphoblastic leukemia (
ALL ) . -
pubmed
PATIENTS AND METHODS :
Patients ( n = 778 ) with newly diagnosed
ALL , 2 to 9 years of age at diagnosis with an initial WBC count less than 10,000 / microL , were eligible for this protocol . -
pubmed
RESULTS :
Patients randomized to receive DI experienced fewer
relapse events in all categories . -
pubmed
Restorations were examined for retention , marginal
caries , marginal microleakage , sensitivity ,
discoloration ,
restorative fracture , and
patient satisfaction . -
pubmed
Translocation ( 11;15;19 ): a highly specific chromosome rearrangement associated with poorly differentiated
thymic carcinoma in young
patients . -
pubmed
We report a 15 - year - old
boy diagnosed with
thymic carcinoma who presented with a large
anterior mediastinal mass ,
pleural effusion , and
bone metastasis . -
pubmed
Several case reports of a similar
chromosomal abnormality have been reported for
thymic carcinoma in young
patients with poor outcome . -
pubmed
This karyotypic abnormality appears to mark a cohort of
patients with
thymic carcinoma who have a poor prognosis despite aggressive chemotherapy . -
pubmed
Treatment of
human brucellosis with
rifampin plus
minocycline . -
pubmed
In order to evaluate the efficacy and tolerability of a high intravenous dose of
rifampin plus oral
minocycline ( administered daily for 3 weeks ) for the treatment of acute
brucellosis , we retrospectively reviewed the outcome of 239 consecutive
patients ( 135
adults and 104
children ) diagnosed and treated over a 17 - year period in Italy . -
pubmed
[ Investigations and public health aspects on
human toxoplasmosis ] . -
pubmed
[ Histochemical studies on cure process of
ascitic tumors of
rats ] . -
pubmed
[ PREVENTIVE ACTION OF
CYSTAMINE AND SOME OF ITS DERIVATIVES IN EXPERIMENTAL
TOXIC PULMONARY EDEMA IN LABORATORY
ANIMALS ] . -
pubmed
METHODS : The clinical presentation of
pertussis was studied in
children who participated in a randomized , controlled clinical trial of efficacy of acellular
pertussis vaccine . -
pubmed
Children who received an antibiotic had a duration of
cough 6 to 11 days longer and
spasmodic cough 4 to 13 days longer than untreated patients . -
pubmed
Girls had a duration of
spasmodic cough 7 days longer than
boys only after 3 years of age . -
pubmed
Streptococcus pneumoniae remains the most important pathogen ; however , emerging resistance of this organism to antimicrobial agents has affected empirical treatment of
CAP . -
pubmed
Is the abuse of cannabis related to psychopathology , HIV /
HCV risk - taking and
infectious diseases ? -
pubmed
METHOD : Overlapping samples of either the entire clinic population ( n = 283 ) or all the patients who had completed 1 year of
MMT treatment ( n = 196 of which 20 were re - entering ) underwent random and twice - weekly observed urine analysis for various drugs of abuse , responded to self - report questionnaires ( SCL-90 - R ; HIV /
HCV risk - taking behaviours ; n = 164 ) , interviews ( ASI , n = 176 ; SCID , n = 151 ) and
hepatitis C and
HIV testing ( n = 149 ) . -
pubmed
Cannabis abusers did not suffer from more psychological distress ,
infectious diseases , and did not engage in more
HCV / HIV risk - taking behaviour , nor did they leave treatment earlier than NCAs . -
pubmed
Patients referred for surgical lung biopsy as part of a diagnostic evaluation of
interstitial lung disease (
ILD ) were evaluated . -
pubmed
MATERIAL AND METHODS : A total of 167
people with
myopia ( 117
women and 50
men ) of the age between 12 and 51 were examined . -
pubmed
Shortly after CVVH , the
patient was diagnosed with
HIT and placed on an
Argatroban infusion . -
pubmed
This case report summarizes the use of
Argatroban during VAD and ECMO support for a
patient diagnosed with
HIT . -
pubmed
The value of
thalidomide -
dexamethasone was assessed in 26 consecutive , previously untreated
patients with
multiple myeloma of high
tumor mass . -
pubmed
There were no occurrences of grade 3 or 4
neutropenia or
thrombocytopenia , so that serious
infection occurred in only 12 % of
patients . -
pubmed
Vagus nerve stimulation suppresses
pain but has limited effects on
neurogenic inflammation in
humans . -
pubmed
Left vagus nerve stimulation reduces
pain perception in
humans . -
pubmed
To test whether VNS also affects activation of primary nociceptive afferents in
humans , we investigated 11
patients before and after implantation of a vagus nerve stimulator by using tonic pressure as
pain stimulus . -
pubmed
OBJECTIVE : The purpose of this study was to test the hypothesis that no significant difference exists in the speech outcomes between
patients with severe
velopharyngeal incompetence (
VPI ) who receive a pharyngeal flap and
patients with less severe
VPI who receive a Z - plasty for management of
VPI . -
pubmed
Modified technique of hepatic vascular exclusion : effect on
blood loss during complex mesohepatectomy in
hepatocellular carcinoma patients with
cirrhosis . -
pubmed
This study was designed to compare the overall outcomes after application of CIO with or without occlusion of the ICV below the liver in complex mesohepatectomy for
hepatocellular carcinoma (
HCC )
patients with
cirrhosis . -
pubmed
CONCLUSIONS : CIO with occlusion of the ICV below the liver is a safe , effective , and feasible technique during mesohepatectomy in
HCC patients with
cirrhosis . -
pubmed
BACKGROUND : The majority of
patients with
hepatitis C virus ( HCV ) infection suffer from disabling
fatigue ,
cognitive dysfunction , and quality of life reduction . -
pubmed
Recent studies have shown that
fatigue and
psychomotor slowing may resolve in
patients with
hepatitis C after treatment with
ondansetron . -
pubmed
This observation indicates alteration of serotonergic neurotransmission in
HCV infected patients with
chronic fatigue . -
pubmed
METHODS : Data from 20
HCV infected patients who were referred to our clinic because of disabling
fatigue and
cognitive decline of unknown cause were analysed retrospectively . -
pubmed
RESULTS : All
patients had pathological results on the
fatigue impact scale . -
pubmed
Comorbidity that could have
impaired cerebral function was excluded in all
patients . -
pubmed
CONCLUSION : Our findings indicate alteration of serotonergic and dopaminergic neurotransmission in
HCV infected patients with chronic
fatigue and
cognitive impairment . -
pubmed
alpha - TEA inhibits survival and enhances
death pathways in
cisplatin sensitive and resistant
human ovarian cancer cells . -
pubmed
Pro -
death and pro - life signaling pathways were studied to understand the anti -
cancer actions of
alpha - TEA on
cisplatin - sensitive (
A2780S ) and -resistant (
A2780 / cp70R )
human ovarian cancer cells . -
pubmed
In this experimental study , the functional changes of the endothelial cells were investigated in the aortic rings of
rats subjected to 50 mg
Si / kg
body weight in their drinking water for 8 days . -
pubmed
The case describes a 38 - year - old
woman presenting a
multilocular radiolucency affecting the entire right half of the lower jaw , with an unerupted third molar displaced to the region of the coronoid process . -
pubmed
It has been proven that HAART is effective in suppressing
human immunodeficiency virus ( HIV ) replication , decreasing morbidity and mortality associated with
HIV and improving quality of life in adults as well as children infected with HIV . -
pubmed
Probiotic treatment of
rat pups normalises
corticosterone release and ameliorates
colonic dysfunction induced by maternal separation . -
pubmed
This paper describes the application of proteomics to incised
wounds of the
rat to determine if this technology could be applied to the important forensic issue of determining the age of
wounds . -
pubmed
Experimental incised skin
wounds were inflicted on
rats 5 , 15 , 30 and 60 minutes , 3 , 6 , 12 and 24 hours and 2 , 5 , 7 and 12 days before euthanasia . -
pubmed
BACKGROUND : Uterine artery embolization ( UAE ) is promising , minimally invasive therapy being offered to
women for treatment of
fibroids . -
pubmed
CASE : A
patient treated with UAE for a huge
cervical fibroid presented with an infected ,
necrotic cervical mass lesion 4 weeks after the procedure . -
pubmed
Spontaneous vaginal expulsion of the infected
cervical fibroid from the left lateral cervical
fistula tract occurred 3 weeks later while the
patient was receiving antibiotic therapy . -
pubmed
METHODS : We studied retrospectively the medical records of 42 eyes of 42
patients with persistent
cystoid macular edema secondary to
BRVO , eyes in which the foveal thickness was greater than 250 microm at final examination . -
pubmed
CONCLUSIONS :
Oral mucositis in
patients who have undergone bone marrow transplantation can be quantified reliably with the easily administered PROMS scale . -
pubmed
The PROMSscale provides a valid measure of the impact of
oral mucositis on the oral - health - related quality of life of
patients affected by this malady . -
pubmed
OBJECTIVES : The aim of this study was to investigate the evolution of lung function during the first 6 years of life after a clinical diagnosis of
cystic fibrosis (
CF ) in infancy in
children with
CF and in healthy control subjects . -
pubmed
MEASUREMENTS AND MAIN RESULTS : Forty - eight
children with
CF and 33 healthy control subjects had up to seven ( median , 3 ) measurements . -
pubmed
Wheeze on auscultation , recent
cough , and
Pseudomonas aeruginosa ( PsA )
infection ( even if apparently effectively treated ) were all independently associated with further reductions in lung function . -
pubmed
PURPOSE : To investigate the effect of multislice computed tomography ( CT ) protocols on the visualization of target vessel stents in
patients with
abdominal aortic aneurysm (
AAA ) treated with fenestrated endovascular grafts . -
pubmed
METHODS : Twenty - one
patients ( 19
men ; mean age 75 years , range 63 - 86 ) undergoing fenestrated endovascular repair of
AAA were retrospectively studied . -
pubmed
Burkholderia cepacia complex (
BCC ) is an opportunistic pathogen that occasionally causes hospital outbreaks . -
pubmed
Human genetic factors and
respiratory syncytial virus disease severity . -
pubmed
SUMMARY : To explain the wide spectrum of disease severity caused by
respiratory syncytial virus (
RSV ) and because of the limitations of animal models to fully parallel
human RSV disease , study of genetic influences on
human RSV disease severity has begun . -
pubmed
They are valuable since an understanding of the direction of a polymorphism 's effect can help construct a meaningful
human RSV disease pathogenesis model . -
pubmed
Chronic prosthetic joint infection caused by
Listeria monocytogenes . -
pubmed
We report what is to the best of our knowledge the first case of persistent
human listeriosis . -
pubmed
Infection of the device with
Listeria monocytogenes occurred and persisted for 2 years . -
pubmed
METHOD : The right musculocutaneous nerve in 16 adult male
Sprague - Dawley rats was transected to induce biceps muscle
paralysis . -
pubmed
Effects of
sphingosylphosphorylcholine against cholestatic oxidative stress and
liver damage in the common bile duct ligated
rats . -
pubmed
The goal of this study was to evaluate the possible protective effects of
sphingosylphosphorylcholine (
SPC ) against
cholestatic oxidative stress and
liver damage in the common bile duct ligated
rats . -
pubmed
Electrocardiographic change after recanalization in a
patient with recent extensive
anterior wall myocardial infarction . -
pubmed
In parallel ,
patients in
end - stage renal failure show an increase in arterial stiffness . -
pubmed
Curiously , the PWV value observed in arms with an AVF was significantly lower in
diabetic than in non - diabetic hemodialyzed
patients ( NDHP ) ( 8.00 + /- ; 2.86 m / s and 10.38 + /- ; 2.33 m / s ; respectively ) . -
pubmed
This diagnosis in a pregnant
patient with
neurofibromatosis type 1 poses additional treatment dilemmas . -
pubmed
Management of pregnant
patients with rare , rapidly growing
tumors may require early delivery in cases where maternal health is in jeopardy . -
pubmed
Outcome of experimental
rat vaginitis by
Candida albicans isolates with different karyotypes . -
pubmed
albicans isolates with b and c karyotypes was analyzed in vivo using a model of experimental
rat vaginitis . -
pubmed
Three
patients developed
hernias following laparotomy from severe injuries sustained during combat . -
pubmed
Canine heartworm is endemic in many parts of the world , and veterinarians rely on rapid in - clinic antigen tests to screen for this
infection . -
pubmed
Because of the widespread use of
heartworm prevention and possible false negative test results in
dogs with low heartworm burdens , the performance of the VetScan VS2 ( ) HW test and a commercially available in - clinic , membrane - based ELISA test ( SNAP ( ) Heartworm RT Test ; IDEXX Laboratories ) was compared using samples from
dogs with low heartworm burdens and/or low levels of circulating antigen . -
pubmed
The purpose of this study was to investigate the mechanisms of aspiration with respect to the viscosity of ingested material in
patients with
dysphagia . -
pubmed
Seventy
patients with
dysphagia underwent videofluoroscopic swallow studies ( VFSS ) between May 1 , 2009 and September 30 , 2009 . -
pubmed
Pleomorphic xanthoastrocytoma : MR imaging findings in 19
patients . -
pubmed
RESULTS : The clinical presentation in 18
patients included :
dizziness ( 8) ;
headache ( 9 ) ; and
epilepsy ( 8) . -
pubmed
Natural killer ( NK ) cell
cytotoxicity was assessed using peripheral blood mononuclear cells from 103 healthy
volunteers and 51
cancer patients . -
pubmed
CASE PRESENTATION : Here we present a 56 - year - old
man with advanced
lung adenocarcinoma who developed a remittent
fever together with
pharyngodynia and
joint pain after first cycle of chemotherapy with
paclitaxel plus
carboplatin . -
pubmed
The
patient was finally diagnosed as
AOSD - like
PNS considering the good and prompt response to a short - term administration of non - steroidal anti - inflammatory drug and subsequent cycles of effective chemotherapy with
pemetrexed plus
cisplatin . -
pubmed
DISCUSSION AND CONCLUSIONS : Though rare ,
AOSD - like
PNS can be one of the potential diagnoses in
lung cancer patients with
fever of undetermined origin , especially those having no response to antibiotic treatment . -
pubmed
OBJECTIVE : To provide a practical review of the spectrum of possible imaging findings in
patients with
progressive multifocal leukoencephalopathy (
PML ) and to address differentials . -
pubmed
We describe the clinical features and serial NCS findings of a
patient with
PCB /
FS . -
pubmed
Insulin resistance in
patients with
chronic kidney disease . -
pubmed
Insulin resistance ( IR ) plays a central role in the
metabolic syndrome and is associated with increased risk for
CKD in nondiabetic
patients . -
pubmed
IR is common in
patients with mild - to - moderate stage
CKD , even when the
glomerular filtration rate is within the normal range . -
pubmed
In
patients with
end stage renal disease , IR is an independent predictor of
cardiovascular disease and is linked to protein energy wasting and
malnutrition . -
pubmed
The authors review relevant clinical trials looking at the efficiency and safety of
ticagrelor focusing predominantly on the management of
patients with
ACS . -
pubmed
The challenge for prescribers is to identify those most likely to benefit from
ticagrelor treatment while minimizing unnecessary
bleeding events for ' real - world '
ACS patients . -
pubmed
Longitudinal liver stiffness assessment in
patients with
chronic hepatitis C undergoing antiviral therapy . -
pubmed
The effect of antiviral treatment and virologic response on
LS was assessed and compared with untreated
patients with
chronic hepatitis C (
CHC ) . -
pubmed
METHODS : TE was performed at baseline , and at weeks 24 , 48 , and 72 in 515
patients with
CHC . -
pubmed
CONCLUSIONS :
LS decreases during and after antiviral treatment in
patients with
CHC . -
pubmed
Brief report : CANTAB performance and brain structure in pediatric
patients with
Asperger syndrome . -
pubmed
Patients were classified as mild [ no
necrosis or
organ failure (
OF ) ] , moderate ( sterile
necrosis or transient
OF ) , severe [ infected
necrosis (
IN ) or persistent
OF ] , or critical ( IN and persistent OF )
AP . -
pubmed
Three female
patients had a & gt ; 2.5 microg / l increase of
Co ions , associated with head sizes & lt;= 50 mm , clinical symptoms and
osteolysis . -
pubmed
5 - Nitrofuran derivatives were synthesized and their antibacterial activity was investigated using standard
bacterial strains and clinical isolates . -
pubmed
Change in inferior sclera exposure following Le Fort I osteotomy in
patients with
midfacial retrognathia . -
pubmed
This study evaluated the decrease in sclera exposure after maxillary advancement or impaction in
patients with
midfacial hypoplasia . -
pubmed
CONCLUSION : Inferior sclera exposure in
patients with
midfacial hypoplasia and
retrognathia decreases significantly in accordance with the change in the lower eyelid position after maxillary advancement or impaction surgeries . -
pubmed
Over the last 90 years it has become established that some
patients will develop severe
arterial disease of the intracranial brain arteries and suffer
brain infarction . -
pubmed
Smaller
infarctions and
brain atrophy may also be seen and over time there appear to be negative cognitive effects in some
patients , with or without abnormal brain imaging . -
pubmed
Focal mononeuropathies and
pneumococcal meningitis are also more common in these
patients . -
pubmed
Brain infarction in
children can largely be prevented screening
children beginning at age 2 years and instituting regular blood transfusion when the Doppler indicates high
stroke risk ( & gt;200cm / sec ) . -
pubmed
Magnetic resonance imaging and positron emission tomography give evidence of subtle and sometimes overt
brain injury due to
stroke in many
adults , but a preventive strategy for
adults with
SCD has not been developed . -
pubmed
CONCLUSION :
Patients with CA -
AKI sustain more severe
AKI than patients with HA -
AKI . -
pubmed
Tobacco and
alcohol : the relation to
pulmonary tuberculosis in household contacts . -
pubmed
This study aims to detect the hidden household contacts ( HC ) cases early and to examine the relative contribution of
tobacco and
alcohol use to the risk of
TB . -
pubmed
The association between habits (
alcohol user and smoking ) and
TB was found except with chewing
tobacco user ( P & gt ; 0.05 ) . -
pubmed
Effective campaign to discourage use of
alcohol and
tobacco , and awareness programme about the mode of transmission of
TB are needed in community . -
pubmed
However , even if most animal
tumors might be a reliable model to study
human carcinomas , many open questions , related to the opportunities to select and recruit new models in oncology , along with their legal and ethical implications , remain unanswered . -
pubmed
Object retrieval by
Norway rats consists of locomotion to an object , object
seizure , carriage to a refuge and release . -
pubmed
MATERIALS AND METHODS : Twelve
patients with
chronic pancreatitis (
CP ) underwent laparoscopic longitudinal pancreaticojejunostomy ( LPJ ) in our unit . -
pubmed
All 12
patients who underwent laparoscopic LPJ had anteroposterior dimension of the pancreatic head of not more than 3 cm without any
pancreatic head parenchymal calcification and with minimal stone load in the head , hence head coring was not contemplated . -
pubmed
Our first eight
patients who were having more than 12 months ' follow - up had
pain relief and significant
weight gain . -
pubmed
Patients treated with
teriflunomide 14 mg spent significantly fewer nights in hospital for
relapse ( p = 0.009 ) and had lower annualized rates of all hospitalizations ( p = 0.030 ) . -
pubmed
Psoriatic arthritis not only causes functional impairment , but also increases mortality risk of
patients . -
pubmed
Nevertheless , the examination of the role of
human microbiota in illnesses using
animal models of
human diseases reared in defined ( gnotobiotic ) conditions could allow insight into the unusual complexity of the mechanisms involved in the initiation and maintenance of
chronic diseases , including
cancer . -
pubmed
INTRODUCTION :
IGF-1 deficiency in
TM patients in
children and
adolescents has been attributed to
chronic anemia and
hypoxia ,
chronic liver disease ,
iron overload and other associated
endocrinopathies , e.g. -
pubmed
Few data are available in the literature regarding adult
TM patients and
growth disorders . -
pubmed
The mean age of
patients with
GHD was 39.3 years ( range : 25 - 49 years , median : 39 years ) versus 35.8 years ( range : 27 - 45 years , median : 37.5 years ) in
non - GHD patients . -
pubmed
The efficacy of
atomoxetine for the treatment of
children and
adolescents with
attention - deficit / hyperactivity disorder : a comprehensive review of over a decade of clinical research . -
pubmed
Atomoxetine was first licensed to treat
attention - deficit / hyperactivity disorder (
ADHD ) in
children and adolescents in the US in 2002 . -
pubmed
, males / females , patients with co - morbidities ,
children /
adolescents , and with / without prior exposure to other
ADHD medications ) . -
pubmed
Fibromyxomas are rare in
children under 10 years of age . -
pubmed
Although this
tumor is reported most frequently in the mandible for the general population , it has rarely been reported in the mandible in
children & lt;10 years of age . -
pubmed
METHODS : We reviewed the 39 reported cases of
odontogenic fibromyxoma in
children under the age of 10 . -
pubmed
RESULTS : This case represents the seventh case of
odontogenic fibromyxoma of the mandible in a
child under the age of 10 years reported in the English literature . -
pubmed
Left atrial appendage ligation in
patients with
atrial fibrillation leads to a decrease in atrial dispersion . -
pubmed
BACKGROUND : Left atrial appendage ( LAA ) exclusion has been performed in
patients with
atrial fibrillation (
AF ) to prevent
thrombus formation and subsequent cardioembolic events . -
pubmed
The purpose of this study was to evaluate the effect of LAA ligation on P - wave morphology in
patients with
AF . -
pubmed
Eleven
patients had paroxysmal
AF and 4
patients had persistent
AF ( 12 male
patients and 3 female
patients ) . -
pubmed
This is a potential mechanism to explain the role of LAA ligation in maintaining sinus rhythm in
patients with
AF . -
pubmed
Angelica Sinensis attenuates inflammatory reaction in experimental
rat models having
spinal cord injury . -
pubmed
This study was aimed to evaluate the effect of
Angelica Sinensis on experimental
rat models in which
spinal cord injury was induced by studying different factors . -
pubmed
These included a sham control group where only laminectomy was performed ,
SCI group where
SCI was induced and AS /
SCI group where although
SCI was induced but
Angelica Sinensis was also administered to study its effect and draw a comparison with control . -
pubmed
On the basis of this study we concluded that the use of 20 mg / kg
Angelica Sinensis in
rat models can attenuate the secondary damage caused by
SCI and thus help in controlling the pathology of
SCI in
rats . -
pubmed
Of 104
patients , 68 % exhibited one
EV , 30 % two
EVs , and 2 % three EVs . -
pubmed
UNLABELLED :
Epstein - Barr Virus (
EBV ) persists for the lifetime of the infected host despite eliciting strong immune responses . -
pubmed
NK cells can kill
EBV - infected cells undergoing lytic replication in vitro , and studies in both
humans and
mice with reconstituted
human immune systems have shown that NK cells can limit
EBV replication and prevent
infectious mononucleosis . -
pubmed
Genetically determined differences in noradrenergic function : The spontaneously
hypertensive rat model . -
pubmed
The spontaneously
hypertensive rat ( SHR ) displays the behavioral characteristics of
ADHD ( poorly sustained attention , impulsivity ,
hyperactivity ) and is the most widely studied genetic model of
ADHD . -
pubmed
The results of the present study show that noradrenergic function is similarly altered by the early life stress of maternal separation in male and female SHR , while
GABA- and
glutamate - regulation of
norepinephrine release remained unaffected by maternal separation in the control , WKY ,
rat strain . -
pubmed
PATIENTS AND METHODS : Immunohistochemical staining was performed in samples from 288
patients with
clear cell renal cell carcinoma . -
pubmed
Longitudinal analysis of hemostasis biomarkers in
cancer patients during antitumor treatment . -
pubmed
UNLABELLED : ESSENTIALS : Hemostasis biomarkers impact
thrombosis occurrence and survival in
cancer patients . -
pubmed
We performed a longitudinal analysis of hemostatic parameters in 112
cancer patients . -
pubmed
Hemostatic parameters are associated with disease state ,
patients ' prognosis , and the risk of
VTE . -
pubmed
BACKGROUND : Hemostasis biomarkers are known to have an impact on
venous thromboembolism (
VTE ) occurrence and survival in
cancer patients . -
pubmed
PATIENTS / METHODS :
Patients with
cancer of the brain ( n = 39 ) , lung ( n = 41 ) , colon ( n = 15 ) or pancreas ( n = 17 ) were included before initiation of antitumor therapy . -
pubmed
At the last blood sampling time - point before
VTE occurrence , in 13
patients the D - dimer level was above the median , and in seven of these patients it was even above the 75th percentile ; however , the individual course was highly variable . -
pubmed
BACKGROUND :
Borrelia miyamotoi , the agent of
relapsing fever , is a tick - borne spirochete first isolated in Japan in 1994 . -
pubmed
In addition , two cases of
meningoencephalitis caused by
B. - pubmed
RESULTS : In vivo , all the SCID
mice challenged with the components before storage and the RBCs stored for up to 42 days developed the
infection . -
pubmed
Wild - type
mice also developed the
infection when injected with prestorage samples from all components , while a lower number of
mice were infected by RBCs stored for 42 days . -
pubmed
RESULTS : Among 712
patients , 16.8 % experienced
MM , of whom 53.3 % received RBCT . -
pubmed
Patients who received RBCT experienced
MM more commonly ( 30.8 % vs 11.1 % ; P & lt ; .001 ) . -
pubmed
Of the 237 proteins detected , 13 were dysregulated in & gt;=3 of the 6
VS patients versus controls , and 13 were dysregulated ( 12 up , 1 down ) in samples from
patients with class D versus class B hearing . -
pubmed
Virtual
human technology researches decisions about care for patients with
dementia . -
pubmed
CONCLUSIONS :
Clozapine - induced
hypersalivation is the most prevalent adverse effect experienced by
patients treated with
clozapine and negatively impacts on quality of life , particularly if daytime
drooling is present . -
pubmed
Successful treatment of postoperative multidrug - resistant
Acinetobacter baumannii meningitis by
tigecycline . -
pubmed
Here we report a case of postoperative MDR
Acinetobacter baumannii meningitis treated by
tigecycline combined with
colimycin for 21 days . -
pubmed
BACKGROUND : The benefits of combination therapy with
infliximab and
azathioprine have been demonstrated in clinical trials of
patients with
ulcerative colitis (
UC ) and
Crohn ' s disease (
CD ) . -
pubmed
AIMS : We aim to compare long - term outcomes among
patients with
inflammatory bowel disease (
IBD ) treated with sequentially added combination therapy or monotherapy strategies . -
pubmed
METHODS : We performed a retrospective cohort study involving adult
patients with
UC and
CD . -
pubmed
When evaluating the subtypes of
IBD , there was a significant benefit in time to IBD - related surgery among
patients with
CD treated with sequentially added combination therapy ( HR 0.46 , 95 % CI 0.25 - 0.85 ) but not
UC ( HR 0.82 , 95 % CI 0.30 - 2.22 ) . -
pubmed
Improving prevention and care for
HIV and
sexually transmitted infections among men who have sex with men in Cambodia : the sustainable action against
HIV and AIDS in communities ( SAHACOM ) . -
pubmed
To address this issue , KHANA , the largest national
HIV organization in the country developed and implemented the Sustainable Action against
HIV and
AIDS in Communities ( SAHACOM ) project . -
pubmed
Eccrine Syringofibroadenoma in a
Patient with Long - Standing
Exfoliative Dermatitis . -
pubmed
OBJECTIVE : This study aimed to verify the effectiveness of the sound generator ( SG ) associated with the counseling in the treatment of the
tinnitus in
individuals with and without
hearing loss regarding the improvement of the nuisance through Tinnitus Handicap Inventory ( THI ) and Visual Analogue Scale ( VAS ) . -
pubmed
CONCLUSION : The use of the SG was similarly effective in the treatment of the
tinnitus in
individuals with and without
hearing loss , causing an improvement of the nuisance and handicap . -
pubmed
This retrospective study reviewed the
patients treated by MMA for
OSAS between 1995 and 2009 . -
pubmed
CONCLUSIONS : MMA is an effective and stable treatment of
OSAS in selected
patients . -
pubmed
Modeling
Down Syndrome in
Mice . -
pubmed
Listeria monocytogenes , a bacterium that is responsible for
listeriosis , is a very diverse species . -
pubmed
PURPOSE : Recurrent
diverticulitis has been reported in 30 - 50 % of
patients who recover from an episode of diverticular - associated
abscess . -
pubmed
Our aim was to review the outcomes of
patients who underwent non - operative management after percutaneous drainage ( PD ) of colonic diverticular
abscess . -
pubmed
Among the remaining 73
patients , there were no significant differences in demographics or
abscess variables compared to those who underwent elective surgery within 4 months . -
pubmed
Only 7 of 73
patients had documented episodes of
recurrences , while 22
patients later had elective surgery ( 1.1 + - 1.2 years from the index case ) . -
pubmed
This article presents an unusual case of
congenital subcutaneous hamartoma of incisive papilla in a 2 - year - old female
child causing feeding and breathing difficulty . -
pubmed
The last few decades have witnessed a tremendous advancement in understanding the genetic basis of major
human diseases such as
cancer . -
pubmed
Dermatomyositis Induced by
Hepatitis B Virus - related
Hepatocellular Carcinoma : A Case Report and Review of the Literature . -
pubmed
We herein report the case of a 55 - year - old
man with
chronic hepatitis B and
alcoholism who presented with
skin rash . -
pubmed
We therefore diagnosed the
patient with
HCC - induced
dermatomyositis . -
pubmed
Chemical Constituents of Propolis from Vietnamese
Trigona minor and Their Antiausterity Activity against the
PANC-1 Human
Pancreatic Cancer Cell Line . -
pubmed
The
ethanol extract of propolis from the
Vietnamese stingless bee Trigona minor possessed potent preferential
cytotoxicity against
PANC-1 human pancreatic cancer cells in nutrient - deprived medium , with a PC50 value of 14.0 mug / mL. -
pubmed
Among the isolated compounds ,
23 - hydroxyisomangiferolic acid B ( 5 ) and
27 - hydroxyisomangiferolic acid ( 13 ) exhibited the most potent preferential
cytotoxicity against
PANC-1 human pancreatic cancer cells under nutrition - deprived conditions , with PC50 values of 4.3 and 3.7 muM , respectively . -
pubmed
CONCLUSIONS : Although STER failed to achieve en bloc resection in 21.3 %
patients , it was still an effective therapy owing to low residual rate and no
recurrence rate after piecemeal resection . -
pubmed
We immunized
guinea pigs with
trichloroethylene using the Guinea Pig Maximization Test ( GPMT ) and scored the
inflammation on the
guinea pigs ' skin . -
pubmed
SUBJECTS AND METHODS : A total of 232
patients with
RAOU and 123 healthy controls ( HCs ) were enrolled in this study . -
pubmed
The
patients were divided into 2 groups based on the presence ( BD+ : n = 62 ) or absence of
BD ( BD- , n = 170 ) . -
pubmed
Nomogram for prediction of level 2 axillary lymph node
metastasis in proven level 1 node - positive
breast cancer patients . -
pubmed
BACKGROUND : The current management of the axilla in level 1 node - positive
breast cancer patients is axillary lymph node dissection regardless of the status of the level 2 axillary lymph nodes . -
pubmed
The goal of this study was to develop a nomogram predicting the probability of level 2 axillary lymph node
metastasis ( L-2 - ALNM ) in
patients with level 1 axillary node - positive
breast cancer . -
pubmed
MATERIALS AND METHODS : We reviewed the records of 974
patients with pathology - confirmed level 1 node - positive
breast cancer between 2010 and 2014 at the Liaoning Cancer Hospital and Institute . -
pubmed
CONCLUSIONS : Our nomogram could help predict L-2 - ALNM in
patients with level 1 axillary lymph node
metastasis . -
pubmed
Since the initial documentation of
IgG4 - related disease in
patients with
autoimmune pancreatitis in 2001 , a growing body of evidence has been accumulating to suggest that various - virtually all - organs can be affected by
IgG4 - RD . -
pubmed
[ Expression and prognostic value of memory T lymphocyte in
patients with
non - small cell lung cancer following radiotherapy ] . -
pubmed
OBJECTIVE : To investigate the expression and prognostic value of memory T lymphocyte in
patients with
non - small cell lung cancer(
NSCLC ) following radiotherapy . -
pubmed
METHODS : Forty - six
patients with
NSCLC receiving radiotherapy in Ningbo Medical Center Lihuili Hospital from February 2010 to May 2012 were enrolled in the study and 50 healthy
subjects served as the control group . -
pubmed
CONCLUSIONS :
NSCLC patients show a significant immunosuppression at the initial stage after radiotherapy , and then a gradual improvement . -
pubmed
Patients with emergency intubation following
trauma were eligible for inclusion . -
pubmed
Predictors of
enophthalmos among adult
patients with pure
orbital blowout fractures . -
pubmed
Of the 629
patients with
orbital fractures , 87 were pure orbital blowout
fractures . -
pubmed
One case was observed in a 43 - year - old
man with a history of recurrent
pneumothorax who developed
pneumothorax after the surgical biopsy . -
pubmed
A 25 - year - old
woman presenting with
auditory hallucinations was referred to A hospital for examination and treatment . -
pubmed
Immunologically ,
PRRSV - susceptible mononuclear cells are the first line of defense against
microbial infection and responsible for antigen recognition , processing , and presentation to T and B cells ; a critical step in the initiation and development of an effective adaptive immune . -
pubmed
Thus , impairment of normal immune function renders the host less able to resist and/or eliminate secondary infectious agents and partially explains the synergy between
PRRSV and
bacterial and viral co - infections . -
pubmed
Multinomial logistic regression quantified sociodemographic and
HIV - treatment factors associated with incident
microcytic anemia or
ACD over 18 months . -
pubmed
We report the case of a 47 - year - old
man who had
hemoptysis due to a
lung parenchymal injury after nail gun use . -
pubmed
BACKGROUND :
Cancer - related fatigue (
CRF ) is one of the most troubling symptoms of
cancer patients during chemotherapy , and no gold standard for the treatment of
CRF has been established . -
pubmed
OBJECTIVE : This study aimed to examine the effects of the Baduanjin qigong on
patients with
colorectal cancer and
CRF , and to explore its intervention effects . -
pubmed
Ninety
patients with chemotherapy - treated
colorectal cancer and
CRF were randomized to a Baduanjin exercise group or a routine care group . -
pubmed
At 24 weeks , the proportion of
patients with moderate - to - severe
CRF was significantly smaller in the exercise group than in the control group ( 23.2 vs. 59.1 % , p & lt ; 0.01 ) . -
pubmed
CONCLUSIONS : Baduanjin qigong exercise can relieve
CRF in
patients with
colorectal cancer undergoing chemotherapy and can improve their physical activity level and their quality of sleep . -
pubmed
The aims of this study were to ( 1 ) evaluate the sleep quality in
OSA patients with
obesity and ( 2 ) identify the parameters most related to sleep quality in
OSA patients with
obesity . -
pubmed
METHODS : Of the
patients with polysomnography ( PSG ) ,
OSA patients with
obesity (
body mass index [
BMI ] & gt;=25 ) were enrolled and then divided into 2 groups based on the Pittsburg Sleep Questionnaire Index ( PSQI ): patients with good sleep quality ( PSQI & lt;=5 , good sleepers ) and those with poor sleep quality ( PSQI & gt;5 , poor sleepers ) . -
pubmed
In addition , we enrolled
OSA patients without
obesity as a disease control group . -
pubmed
OBJECTIVE : We report the immune response during a case of acute
HEV response in a
patient with an
acute hepatitis E virus ( HEV ) genotype 3 infection in the Netherlands . -
pubmed
RESULTS : The
patient initially presented with features typical of acute
viral hepatitis , with detectable
HEV RNA in blood . -
pubmed
Real time PCR revealed the presence of
HEV in liver tissue , suggestive of active
intrahepatic infection despite clearance in blood . -
pubmed
CONCLUSIONS : Our results support utility of cobas tissue and plasma testing to aid selection of
patients with EGFRm advanced
NSCLC for first - line
osimertinib treatment . -
pubmed
Methods : We conducted a web - based questionnaire survey of 654 19- to 39 - year - old adults who had companion
dogs in Seoul , South Korea , where a major health burden is
depression among young adults . -
pubmed
We measured the owners ' attitudes toward their
dogs using the modified Pet Attitude Scale ( PAS - M ) and their
depression symptoms using the short version of the Center for Epidemiologic Studies
depression scale ( CESD-10 ) . -
pubmed
We present our experience during 5 years , in which we treated 245
patients with
AML , of which we could genetically characterize 48 cases ( 26
females , 22
males ) with a median age of 52 years . -
pubmed
OBJECTIVES : The objective of our study was to assess attention processes and executive function in
patients with
narcolepsy with
cataplexy (
NT1 ) . -
pubmed
METHODS : We studied 28
patients with
NT1 and 28 healthy control
participants matched for age , gender , and educational level . -
pubmed
RESULTS :
Patients had significantly more
daytime sleepiness than controls . -
pubmed
A significant negative correlation between
depression and disease duration was found in NT1
patients . -
pubmed
We emphasized the need to control the influence of processing speed and sustained attention in the neuropsychological assessment of
NT1 patients . -
pubmed
Building upon the development of modern techniques for gene delivery , many gene - based therapies have been effectively used to treat loss - of - function
retinal diseases in
mice and men . -
pubmed
This review article discusses the current indications for PARPIs in both frontline and recurrent settings , current research in combination approaches , and finally , ongoing research on novel methods to target DNA damage response in an effort to exploit the common susceptibility to DNA damage repair in
epithelial ovarian cancer and improve outcomes for
patients . -
pubmed
METHODS : Profiling of the
AT lipidome and fasting serum non - esterified
fatty acid (
NEFA ) composition were conducted in 125
volunteers ( PNPLA3148MM /
MI , n=63 ; PNPLA3148II , n=62 ) . -
pubmed
METHODS : A total of 105
patients who received ultrasonography - guided RFA in the Department of Ultrasound , Chinese PLA General Hospital between April 2014 and August 2018 for benign
thyroid nodule were enrolled in this retrospective study . -
pubmed
METHODS : This was a descriptive register study of all
children aged 6 - 14 years with
injuries from bicycle accidents who were treated at a Danish university hospital in the 1980 - 2014 period . -
pubmed
Timing of
Cataract Surgery in
Giant Cell Arteritis Patients . -
pubmed
METHODS : This retrospective study used ICD-9/10 and Current Procedural Terminology codes to identify all
patients with biopsy - proven
GCA who underwent
cataract surgery from 2005 to 2019 at a single institution . -
pubmed
Excluded from the study were
patients whose date of biopsy diagnosis or dose of
corticosteroids at the time of
cataract surgery was unknown . -
pubmed
Two
patients had a history of
arteritic ischemic optic neuropathy . -
pubmed
CONCLUSIONS :
Cataract surgery appeared safe for
GCA patients on varying doses of
prednisone at time of surgery at least 7 months from time of biopsy diagnosis . -
pubmed
There is a need for a larger cohort of data from neuro - ophthalmologists and
cataract surgeons nationally to establish guidelines for safe
cataract surgery in
GCA patients . -
pubmed
METHODS : Ten
patients with progressive or refractory
cardiogenic shock underwent Impella 5.0 implantation via transcaval access . -
pubmed
We performed in vivo mosaic transgenesis assays in
zebrafish to quantitatively test the enhancer activity of
type 2 diabetes - associated loci Six out of ten tested sequences are endocrine pancreatic enhancers . -
pubmed
Total number of hospital admitted
HF patients as well as new - onset or readmitted
HF patients decreased by 16 , 13 , and 20 % , respectively ( p < .0001 ) . -
pubmed
These studies demonstrate that not only was recapitulation of mechanistic activity supported in
zebrafish , but highly relevant off - target
toxicities observed in higher
vertebrates were identified in
zebrafish , regardless of chorionation . -
pubmed
Deep anterior lamellar keratoplasty with cross - linked acellular
porcine corneal stroma to manage
fungal keratitis . -
pubmed
One
patient developed
fungal reinfection and underwent penetrating keratoplasty . -
pubmed
High output
HF was surgically induced via creation of an
arterio - venous fistula in adult male
Sprague - Dawley rats . -
pubmed
Typhimurium , involved in
human infection outbreaks , should be considered a potential risk for consumers . -
pubmed
Anatomical tracing , chemogenetic , optogenetic and local pharmacological approaches were utilized to investigate the participation of the LPB - l / vlPAG pathway in
itch and
pain sensation in
mice . -
pubmed
MATERIALS AND METHODS : This prospective study included
patients with clinically suspected
CaP that were referred to MRI - fusion biopsy from 2014 to 2019 . -
pubmed
Overall
cancer detection rate was higher in
patients with a positive DRE ( 70.3 % vs 48.9 % , P < 0.05 ) . -
pubmed
BACKGROUND / AIMS : This study aimed to evaluate the real - life efficacy and tolerability of direct - acting antiviral treatments for
patients with
chronic hepatitis C (
CHC ) with / without
cirrhosis in the Turkish population . -
pubmed
MATERIAL AND METHODS : A total of 4,352
patients with
CHC from 36 different institutions in Turkey were enrolled . -
pubmed
CONCLUSION :
LDV /
SOF or
PrOD +- RBV were effective and tolerable treatments for
patients with
CHC and with or without advanced
liver disease before and after liver transplantation . -
pubmed
Although
HCV eradication improves the liver function , there is a risk of developing
HCC . -
pubmed
[ Adrenal phlebography in 35
women with
pilary virilism . -
pubmed
In a
patient with documented
paroxysmal junctional tachycardia (
PJT ) electrophysiologic studies were performed using an extrastimulus technique . -
pubmed
Postural changes in blood pressure were recorded in all 391
patients suffering from
Parkinson ' s syndrome over a period of six years . -
pubmed
Histological examination of the entire central nervous system and the sympathetic ganglia was performed in six
patients suffering from
idiopathic Parksinson ' s disease . -
pubmed
Five of the six
patients had
Lewy bodies in the sympathetic ganglia . -
pubmed
Loss of nerve cells was noted in the sympathetic ganglia in those
patients that demonstrated
postural hypotension . -
pubmed
Strains ( 115 ) of
Bacteroides fragilis were identified at the subspecific level and were tested for susceptibility to
ampicillin ,
cephalothin ,
chloramphenicol ,
clindamycin ,
penicillin , and
tetracycline using an agar dilution technique . -
pubmed
We tested the following
strains :
B. - pubmed
Mouse mammary
tumor virus (
MMTV ) is a milk - transmitted retrovirus involved in the neoplastic transformation of
mouse mammary gland cells . -
pubmed
A
patient treated for
ovarian epithelial cancer by total abdominal hysterectomy ( TAH ) , bilateral salpingo - oophorectomy ( BSO ) , total omentectomy and five courses of single agent
carboplatin chemotherapy , developed retroperitoneal
fibrosis . -
pubmed
The protocol asked for
volunteers ,
epileptic cases and
patients with
Alzheimer ' s disease . -
pubmed
The retrospective analysis has concerned 323
patients with
acute nonlymphocytic leukaemia (
ANLL ) . -
pubmed
The comparable
patients groups were treated since 1981 according to protocols used by the Polish
Acute Leukaemia Group ( induction ; modified TAD or
Adriamycin plus
Ara - C , maintenance ; rotatingly changed polychemotherapy for 3 years ) . -
pubmed
The scoring system has been elaborated allowing selection of
ANLL patients to standard risk group and a high risk group . -
pubmed
[ Pathology of the gastrointestinal tract in
patients with
reactive arthritis and its possible role in the pathogenesis of the disease ] . -
pubmed
It presents in older
patients as a
mass lesion and usually remains localized . -
pubmed
Twelve
patients with
conjunctival lymphoma were treated at the Massachusetts General Hospital between 1979 and 1988 . -
pubmed
Two of 12
patients were found to have
systemic disease at the time of presentation . -
pubmed
One
patient developed
conjunctival lymphoma 5 years after the diagnosis of generalized disease . -
pubmed
One of 12
patients died of systemic disease 4 years after treatment of the
ocular lesion . -
pubmed
Two
patients developed
cataracts 4 and 5 years after treatment ; one had bilateral
cataract , although only one eye had been treated . -
pubmed
The effects of intraarterial chemotherapy with
cisplatin on
rabbit VX2 carcinoma transplanted to the hind legs of animals were studied . -
pubmed
The author concludes that significant ultrastructural changes can be demonstrated by the regional administration of
cisplatin in
rabbit VX2 carcinoma and that these promising results should be followed by clinical trials . -
pubmed
A histomorphometric analysis of trephine biopsies of bone marrow from 65
patients with
chronic myeloid leukemia . -
pubmed
A histomorphometric ( planimetric ) study was performed on trephine biopsies of the bone marrow taken at presentation from 65
patients ( 31 males and 34 females , with a median age of 48 years ) with
chronic myeloid leukemia (
CML ) . -
pubmed
Specimens from 20
patients ( 9
males and 11 females , with a median age of 53 years ) without any
hematologic disorders served as controls . -
pubmed
The
CML patients were separated into two groups with different survival patterns . -
pubmed
Seven
patients reported an improvement in the level of
fatigue , the partial pressure of
carbon dioxide fell significantly ( 6.5 + /- 0.9 to 6.1 + /- 0.9 kPa : P less than 0.01 ) and there was a slight bronchodilator effect [ forced expiratory volume in 1s ( FEV1 ) 0.60 + /- 0.18 to 0.71 + /- 0.2 1s-1 : P less than 0.02 ] after 6 months . -
pubmed
The drug was generally well tolerated but three
patients with pre - existing
biliary tract disease developed
obstructive jaundice . -
pubmed
We tested if specific inhibition of recruitment of leukocytes across the blood brain barrier from the vascular compartment to the cerebrospinal fluid ( CSF ) space reduced tissue damage and improved the outcome of
infection in a
rabbit model of experimental
meningitis . -
pubmed
Animals receiving the antibody experienced a delay in the development of
bacteremia and a significantly reduced inflammatory response during
ampicillin - induced
bacterial killing . -
pubmed
Alveolar echinococcosis , a serious and often fatal
human disease , can be efficiently cured only by complete surgical resection of the
Echinococcus multilocularis lesion . -
pubmed
Six of 7 additional
patients who showed
recurrences in an average of 6 years after surgery despite assumed complete surgical resection , were positive by Em2 - ELISA at the time of
recurrence . -
pubmed
[ Lipid peroxidation in the etiology of
sudden death and the mechanisms of its activation in the myocardium of
patients with
ischemic heart disease ] . -
pubmed
Comparison of
cefotaxime ,
imipenem -
cilastatin ,
ampicillin -
gentamicin , and
ampicillin -
chloramphenicol in the treatment of experimental
Escherichia coli bacteremia and
meningitis . -
pubmed
Pathological changes in the teeth and tooth appendages of the
rat in
radiation sickness . -
pubmed
The records of 104
patients with primary
adenocarcinoma of the duodenum were reviewed . -
pubmed
Regulation of alternative pathways of
glucose metabolism in
rat heart in
alloxan diabetes : changes in the
pentose phosphate pathway . -
pubmed
The flux of
glucose through the
pentose phosphate pathway , important in relation to the provision of
ribose 5 - phosphate for
nucleotide and RNA synthesis , was decreased by 70 % in the
diabetic rat heart in parallel with a similar decreased flux through the glycolytic route . -
pubmed
We report an
infant with classical
phenylketonuria (
PKU ) who had unusually high serum
phenylalanine at 12 days of life ( 5200 mumol ; greater than 3.2 SD above our mean for
PKU at 10 - 15 days of age ) while on parenteral nutrition , despite a relatively high tolerance for
phenylalanine on oral feeds at 3 - 4 months of life ( 97 - 128 mg / kg / day ; normal for
PKU : less than 90 mg / kg / day ) . -
pubmed
Identification of
PKU was somewhat delayed in this
child because of failure to recognize that parenteral nutrition provides a
phenylalanine load equivalent to or greater than the routine oral formula feeding . -
pubmed
This study demonstrates that significant baroreflex - mediated regulation of
vasopressin can occur in
humans in the absence of overt
hypotension . -
pubmed
[ Correlation of noninvasive parameters of myocardial function in
patients with
postinfarction cardiomyopathy ] . -
pubmed
A comparison of breathing pattern between transient and steady state
hypoxia in awake
dogs . -
pubmed
Computerized tomographic scan findings in
patients with
autistic behavior . -
pubmed
An analysis of the computerized tomography scans of 17
patients with
autistic behavior was carried out by investigators independent from those selecting the subjects . -
pubmed
Useful determinants of prognosis for
patients with metastatic
cancer of the stomach . -
pubmed
Pretreatment absolute granulocyte ( less than 6,000 / cu mm ) , lymphocyte ( greater than 1,500 / cu mm ) , and monocyte ( 300 to 900 / cu mm ) counts are three independent indicators of good prognosis for
patients with metastatic
gastric cancer . -
pubmed
Serum and peripheral blood lymphocytes from 10
patients with
Crohn ' s disease and 10 healthy subjects were examined for immunological reactivity against
chick embryo cell cultures displaying cytopathic effects after inoculation with 0.2 micro filtrates prepared from
Crohn ' s disease intestinal tissues . -
pubmed
The clinical trial indicated that both algorithms were fairly comparable and that their primary use would be as teaching aids for medical students and residents to suggest various diagnostic possibilities for
hypercalcemia in
patients . -
pubmed
A group of
patients with
portal - systemic encephalopathy were studied . -
pubmed
The effects of
zinc deficiency on oral behaviour and taste bud morphology in
chicks . -
pubmed
PURPOSE : To evaluate the prevalence of
autoimmune thyroid disease and
thyroid dysfunction in
patients with primary
Sjogren ' s syndrome . -
pubmed
PATIENTS AND METHODS : Thyroid function of 33
patients with primary
Sjogren ' s syndrome was clinically and biochemically evaluated . -
pubmed
CONCLUSIONS : The high prevalence of
autoimmune thyroid disease and
thyroid dysfunction found in primary
Sjogren ' s syndrome , using sensitive immunologic and thyroid function tests , suggest that both diseases are more frequently associated than it was previously thought , and should be sought clinically and by laboratory tests in all
patients with primary
Sjogren ' s syndrome . -
pubmed
Bullous congenital ichthyosiform erythroderma is a
human hereditary skin disorder in which suprabasal keratinocytes rupture . -
pubmed
Pityrosporum ovale in healthy children ,
infantile seborrhoeic dermatitis and
atopic dermatitis . -
pubmed
Twenty
children with
ISD and twenty healthy infants were subjected to culture for
P. - pubmed
ovale cultures in 60
patients with
AD , 40
patients with
rhinoconjunctivitis and/or
asthma (
RA ) and 40 children and young adults with no
atopic history ( HC ) . -
pubmed
ovale was evaluated with a skin prick test ( SPT ) and RAST and compared in 3 groups (
AD , RA , HC ) of
patients aged 0 - 20 years . -
pubmed
In
patients with
AD on different parts of the body , 15 % had a positive SPT to
P. - pubmed
In another group of
patients , aged 14 - 53 years , with
AD localised mainly to the head and neck area , the SPT was positive in 55 % of the
patients . -
pubmed
A prospective study of 21
patients with the diagnosis of
non - alcoholic steatohepatitis (
NASH ) was carried out . -
pubmed
18
patients were
obese , 2 of them
diabetic , 2 others had a history of exposure to drugs (
amiodarone and
isopropilic alcohol ) and the last one presented
hypothyroidism . -
pubmed
4 were
females out of which one was pregnant during the appearance of
brain metastases . -
pubmed
Pharmacokinetics and acute cardiovascular effects of
menogaril in
patients with
metastatic tumors . -
pubmed
Menogaril ( 200 mg / mg ) was infused over 90 minutes to 4
patients with metastatic
colon or prostate cancer . -
pubmed
A 58 - year - old
man with common variable
immunodeficiency ,
splenomegaly , and
hemolytic anemia . -
pubmed
Photosensitivity - induced
retinal atrophy in albino
rat . -
pubmed
Pentylenetetrazol elicits
epileptiform activity in the dentate gyrus of the
urethane anesthetized
rat by activation of the entorhinal cortex . -
pubmed
In the
urethane anesthetized
rat ,
pentylenetetrazol produces a characteristic
epileptiform discharge in the dentate gyrus . -
pubmed
In other
animals tetrodotoxin (
TTX ) was injected into the right entorhinal cortex before the onset of
epileptiform activity ( n = 5 ) . -
pubmed
Results , principles and pitfalls in the management of renal
AA - amyloidosis ; a 10 - 21 year followup of 16
patients with
rheumatic disease treated with alkylating cytostatics . -
pubmed
OBJECTIVE : To assess renal functional outcome at 10 - 21 years in 16 consecutive
patients with
rheumatic disease , treated with alkylating agents for secondary renal AA -
amyloidosis , and to review management principles developed during 21 years . -
pubmed
RESULTS : Of the 7 cases of precipitous
uremia that occurred , 4 were not treated with cytostatics at the
patients ' local hospitals . -
pubmed
They presented with bilateral central predescemetic avascular
haze associated with mild
corneal stromal edema ,
descemetic folds in one
patient and
polymegethism on endothelial specular microscopic examination . -
pubmed
The
vision impairment was severe , unilateral in one
patient and bilateral in the other . -
pubmed
PURPOSE : We evaluated the safety and efficacy of a new transfusion regimen for
children with severe
anemia . -
pubmed
Throughout the transfusion , the
patients were closely monitored for any clinical signs of
heart failure . -
pubmed
RESULTS : No
patient developed any signs of
cardiac failure or increase in the heart rate during or after the completion of transfusion . -
pubmed
Excluding the four
patients with
sickle cell anemia , the remaining 18
patients had a mean increase in the hematocrit of 1.04 % per 1 cc / kg of PRBC ( range 0.85 - 1.28 ) . -
pubmed
CONCLUSION : We conclude that for
children with severe
anemia of gradual onset requiring transfusion therapy , continuous transfusion of PRBC at the rate of 2 cc / kg / h is a safe and effective regimen resulting in an increase in the hematocrit of approximately 1 % for each 1 cc / kg of PRBC transfused in all
patients , except patients with
sickle cell anemia . -
pubmed
Multiple
cutaneous mast cell tumours in a
cow . -
pubmed
Criteria for abnormal
SAE in
children classified according to age were filtered QRS duration ( f - QRSd ) & gt ; 95 msec , root mean square ( RMS ) & lt ; 30 mu v and duration of low amplitude signal ( LAS ) & gt ; 25 msec in those under 3 months old ; f - QRSd & gt ; 110 msec , RMS & lt ; 25 mu v , LAS & gt ; 30 msec in those 3 months or more but less than 1 year old ; f - QRSd & gt ; 115 msec , RMS & lt ; 20 mu v , LAS & gt ; 30 msec in those 1 year old or more but less than 12 year old ; and f - QRSd & gt ; 125 msec , RMS & lt ; 20 mu v , LAS & gt ; 30 msec in those 12 year old or more . -
pubmed
Reduction of
brain injury using
heparin to inhibit leukocyte accumulation in a
rat model of transient focal
cerebral ischemia . -
pubmed
They evaluated the efficacy of sulfated polysaccharides ( unfractionated heparin , low - molecular - weight heparin ,
heparan sulfate ,
chondroitin sulfate C , and
dextran sulfate ) on leukocyte accumulation ,
infarction size , and neurological outcome after transient focal
cerebral ischemia in
rats subjected to 1 hour of
ischemia and 48 hours of reperfusion . -
pubmed
Ibotenic acid lesions of the superior colliculus produce longer lasting deficits in visual orienting behavior than
aspiration lesions in the
cat . -
pubmed
Four
animals with aspiration lesions initially showed an
hemianopia in the contralateral hemifield which recovered fully in 4.5 weeks or less . -
pubmed
In these
animals the
contralateral hemianopia persisted for an average of 16.6 weeks , but may have persisted longer had we not intervened by either sacrificing the
animal or ablating the visual cortex contralateral to the SC lesion . -
pubmed
Forty - one distal femora , from
human cadavers with a mean age of 45 years ( range : 23 to 70 years ) at the time of
death were studied . -
pubmed
We administered
rhSOD1 as an acute bolus in three
sheep and 16
human subjects with
amyotrophic lateral sclerosis (
ALS ) . -
pubmed
administration of 20 micrograms of
rhSOD1 in
ALS subjects revealed a mean elimination half - life of 2.2 + /- 0.8 hours , clearance of 1.2 + /- 0.6 ml per hour , and volume of distribution of 3.5 + /- 0.4 ml . -
pubmed
We detected no benefit of this treatment in the two
patients with
familial ALS . -
pubmed
Human non - small - cell lung cancer (
NSCLC ) is considered to be a chemotherapy - refractory
malignancy . -
pubmed
STUDY DESIGN : Invasive
cervical cancer was diagnosed in 12 pregnant
women between 1 January 1977 and 1 January 1996 . -
pubmed
Ten
patients had FIGO ( International Federation of Gynaecology and Obstetrics ) stage IB
lesions , two
patients stage IIA / B. -
pubmed
Eight
patients had
squamous cell carcinoma , four
adenocarcinoma . -
pubmed
Two
patients , one in each group , died after a
relapse . -
pubmed
CONCLUSION : Delayed treatment to achieve greater fetal maturity is a reasonable option for
patients with cervix
carcinoma of & lt;stage IIB ,
non - bulky tumours and a gestation of & gt;20 weeks . -
pubmed
PATIENTS AND METHODS : Parenchymal function was assessed by quantitative salivary gland scintigraphy performed prospectively in 50
patients with
differentiated thyroid cancer before and 3 months after HD - RIT with either 3 GBq
iodine (
( 131 ) I ) ( n=21 ) or 6 GBq
( 131 ) I ( n=29 ) in a double - blind , placebo - controlled study . -
pubmed
Nine control
patients developed grade I and two grade II
xerostomia . -
pubmed
Three months after HD - RIT , parenchymal function of salivary glands was not significantly altered ( P=.691 ) and
xerostomia did not occur in any of these
patients . -
pubmed
CONCLUSION : Parenchymal damage in salivary glands caused by HD - RIT can significantly be reduced by
amifostine , which may improve the quality of life of
patients with
differentiated thyroid cancer . -
pubmed
HYPOTHESIS : There is no difference in the effects produced in
patients suffering from smooth bronchiolar
muscle spasm by
metaproterenol when delivered either by a standard metered - dose inhaler or with a hand - held nebulizer . -
pubmed
PARTICIPANTS : Consecutive prehospital
patients complaining of difficulty breathing with clinical evidence of
bronchospasm and with a history of
asthma ,
chronic obstructive pulmonary disease , or
emphysema who were not in extremis . -
pubmed
Human immunodeficiency virus type 2 ( HIV-2 )- infected baboons (
Papio cynocephalus ) provide a valuable animal model for the study of
acquired immunodefidency syndrome (
AIDS ) pathogenesis since many features of
disease progression resemble
HIV-1 - infection of
humans . -
pubmed
Effects of chelator treatment on aorta and corpus cavernosum from
diabetic rats . -
pubmed
The aim was to evaluate the effects of treatment with the
transition metal chelator
trientine on endothelium - dependent relaxation of aorta and corpus cavernosum from
streptozotocin - induced
diabetes of 8 weeks duration in
rats . -
pubmed
Reversal treatment ( 4 weeks untreated
diabetes , 4 weeks
trientine ) did not effect endothelium - dependent relaxation compared with aortas from
rats with 4 weeks of
diabetes , however , there was a 22.5 + /- 6.2 % improvement compared with 8 weeks of
diabetes . -
pubmed
The purpose of this study was to determine whether a viability threshold could be identified from this measure in
patients with
acute myocardial infarction treated in a homogeneous manner with successful reperfusion therapy . -
pubmed
METHOD AND RESULTS : The study group consisted of 61
patients with acute
myocardial infarction with a risk area of & gt;6 % LV treated with primary angioplasty between 120 and 240 minutes after symptom onset . -
pubmed
Infarct location was anterior in 22 and inferior in 39
patients . -
pubmed
MAR was 33+/-15 % LV and IS was 13+/-15 % LV : 23
patients had no
infarction despite MAR similar to those with
infarction . -
pubmed
Receiver - operator characteristic curve analysis identified a nadir value of 0.26 as providing the best separation of
patients with and without
infarction ( sensitivity , 74 % ; specificity , 74 % ) . -
pubmed
Cognitive improvement following rehabilitation in
patients with
COPD -
pubmed
Hypermagnesemia in a pediatric
patient . -
pubmed
This case report describes an accidental
overdose of
magnesium that occurred in an 18 - month - old
girl during a routine operation . -
pubmed
The
patient recovered without
neurological deficits . -
pubmed
Furthermore , histopathological study of the livers of immunized
mice showed that
granulomas formed around eggs were diminished in both size and number . -
pubmed
Inhaled vs oral
steroids for
adults with chronic
asthma . -
pubmed
OBJECTIVES : To determine therapeutically equivalent doses of inhaled versus oral
steroids for
adults with
chronic asthma . -
pubmed
SELECTION CRITERIA : Randomised controlled trials were selected of at least 4 weeks duration and included
patients over the age of 15 years with chronic
asthma . -
pubmed
Essential role of neutrophils in the initiation and progression of a
murine model of
rheumatoid arthritis . -
pubmed
Neutrophils are prominent participants in the
joint inflammation of
human rheumatoid arthritis (
RA )
patients , but the extent of their role in the inductive phase of joint
inflammation is unknown . -
pubmed
In the K / BxN
mouse RA model , transfer of autoreactive Ig from the K / BxN
mouse into
mice induces a rapid and profound joint - specific inflammatory response reminiscent of
human RA . -
pubmed
We observed that after K / BxN serum transfer , the earliest clinical signs of
inflammation in the ankle joint correlated with the presence of neutrophils in the synovial regions of recipient
mouse ankle joints . -
pubmed
Mice were treated with a neutrophil - depleting mAb before and following transfer of arthritogenic serum and scored for clinical indications of
inflammation and severity of swelling in ankle joints and front paws . -
pubmed
[ Evaluation of immunity against
Venezuelan equine encephalitis virus and
dengue in the
human population of San Carlos , the Almirante Padilla Island Municipality , Zulia State , Venezuela . -
pubmed
During the last epidemic outbreak ( 1995 ) , the studies reported a great number of cases of
VEE in
humans , based on epidemiologic - clinical diagnosis ; occupying this municipality , the first place in the attack rate by the virus . -
pubmed
Given the fact that
simian immunodeficiency virus ( SIV ) infection in
rhesus macaque is a well - characterized model for
human immunodeficiency virus (
HIV ) , it is of great interest to develop an efficient protocol to transduce
rhesus macaque primary T cells . -
pubmed
We examined 170
patients with
acute viral hepatitis B (
AVH - B ) and 10
patients with
chronic hepatitis B ( CH - B ) exacerbation . -
pubmed
METHODS : Of 354
patients who underwent a TEE study in our laboratory during the study period , 106 were referred for detection of a source of
embolism . -
pubmed
Protruding arch
atheromas were present in 42
patients ( 47 % ) and absent in 47 ( 53 % ) . -
pubmed
Nine
subjects showed no
convulsion . -
pubmed
Subjects who showed
seizure ( age 37.7 + /- 13.2 years ) were younger ( t = 4.178 , df = 19 , p = 0.00025 , one - tailed ) than those who did not ( age 57.6 + /- 6.1 years ) . -
pubmed
The aim of the present study was to evaluate long - term efficacy of a
patient education programme in an
asthma out - patient clinic . -
pubmed
Of 1024
human cancer - focused genes arrayed , 187 genes were up - regulated and 72 genes were down - regulated at least 2 - fold by DC . -
pubmed
These bradyzoites did not appear to be functionally mature ; they did not induce patent
infections in
dogs . -
pubmed
Respiratory tract infections caused by
Bordetella pertussis are occasionally accompanied by severe
neurologic disorders and
encephalopathies . -
pubmed
These findings support the existence of numerous regulatory mechanisms in the
TM and may help explaining the low percentage of
glaucoma patients associated with each mutated
glaucoma gene . -
pubmed
Infection of the upper respiratory tract of the chick with a mild ( vaccine )
strain of
Newcastle disease virus : I. Initiation and spread of the
infection . -
pubmed
A new record of
human infection with
Dipylidium caninum in the United States . -
pubmed
Ultrasound examination of the IOM in 46 forearms from 18 normal
volunteers , five
patients with
restricted forearm pronation and supination , and two preoperative cases was performed to determine the usefulness and reproductivity of this examination . -
pubmed
Teloptosis and kenogen : two new concepts in
human trichology . -
pubmed
Posthypoxic myoclonus (
PHM ) is a
syndrome of action and intention
myoclonus that occurs in some
patients who survive a
cardiac arrest . -
pubmed
Interventions such as deep brain stimulation that interrupt networks that involve these structures may be useful in
patients with severe
PHM . -
pubmed
OBJECTIVE : To identify the brain regions associated with the cognitive generation of affect in
hypomanic bipolar patients . -
pubmed
METHODS : The study examined 10
hypomanic female
subjects with
bipolar affective disorder , and 10 age- and sex - matched comparison subjects using functional magnetic resonance imaging ( fMRI ) while viewing alternating blocks of captioned - pictures designed to evoke negative , positive or no affective change . -
pubmed
CONCLUSIONS : This preliminary study suggests that
hypomanic patients recruit additional subcortical limbic systems for emotional evaluation when advanced prefrontal cortical processing is no longer sufficient . -
pubmed
The
patient died of
aortic rupture on the 7th postoperative day . -
pubmed
Guinea pigs are often used as an animal model of
human tuberculosis (
TB ) . -
pubmed
However , there are few methods available for pursuing the immunological processes involved in
guinea pig TB . -
pubmed
We showed that these RT - PCR primer sets could be used to examine mRNA expression semi - quantitatively in
guinea pig tissues , and conclude that these newly designed primer sets for conventional RT - PCR will be useful for studying the immunological processes in
guinea pig tuberculosis experiments to investigate and evaluate efficacy of new vaccines or anti - mycobacterial drugs . -
pubmed
PATIENTS AND METHODS : We report on a female
patient who developed
keratectasia in both eyes 4 weeks after LASIK . -
pubmed
Previously reported non - luminous
strains , which had been identified phenotypically as
P. - pubmed
Noninvasive ventilation to prevent
respiratory failure after extubation in high - risk
patients . -
pubmed
OBJECTIVE : Compared with standard medical therapy ( SMT ) , noninvasive ventilation ( NIV ) does not reduce the need for reintubation in unselected
patients who develop
respiratory failure after extubation . -
pubmed
PATIENTS : Ninety - seven consecutive
patients with similar baseline characteristics , requiring & gt;48 hrs of mechanical ventilation and considered at risk of developing postextubation
respiratory failure ( i.e. -
pubmed
PURPOSE OF REVIEW : Changes in epidemiology and advances in the treatment of
coronary artery disease ,
hypertension and
diabetes mellitus have increased the prevalence of
heart failure in the general population , and also the number of
patients with
heart failure presenting for surgery . -
pubmed
Particularly in the perioperative period ,
patients with chronic
heart failure are faced with numerous triggers of acute decompensation that can partly be avoided or treated . -
pubmed
Patients without preexisting
myocardial contractile dysfunction may sustain severe perioperative complications , e.g. -
pubmed
RECENT FINDINGS :
Patients with preexisting
heart failure undergoing non - cardiac surgery suffer substantial morbidity and mortality despite advances in perioperative care . -
pubmed
The importance of
heart failure as an independent risk factor is underlined by the fact that
patients with
coronary artery disease but without
heart failure have a similar 30 - day mortality rate to the general population . -
pubmed
Streptococcus pyogenes is a Gram - positive bacterium that causes several diseases , including
acute tonsillitis and
toxic shock syndrome . -
pubmed
RECENT FINDINGS : The incidence of
POF is increasing largely due to improved survival rates of
cancer patients treated with radiation and chemotherapy . -
pubmed
For
patients with
extracapsular extension , the survival curves separate depending on whether positive or
negative surgical margins are obtained . -
pubmed
CASE : We report on a 30 - year - old
woman who desired to preserve her fertility with well - differentiated endometrial
adenocarcinoma . -
pubmed
In the pathogenesis of a variety of adult
human diseases such as
cancer and
cardiovascular disorders , ROS cause an enhancement of
tissue injuries . -
pubmed
Primary classic penile
Kaposi ' s sarcoma in an elderly
HIV - negative patient : report of a case and review of the literature . -
pubmed
Firstly , we induced
chromosomal breaks in the offspring of a 5H addition line of common
wheat carrying a gametocidal chromosome and cytologically screened for plants with structural chromosomal changes involving 5H , such as deletions and translocations . -
pubmed
Acute
thrombosis in native
arterio - venous fistulae (
AVF ) results in considerable
patient morbidity . -
pubmed
Between 1992 - 2000 , 21 episodes of acutely thrombosed
AVF in 15
patients ( 9
females ; age range 29 - 80yrs ) were referred for intervention . -
pubmed
Five
patients had
recurrence of
thrombosis & gt;3 months after the primary procedure , 3 had successful reintervention . -
pubmed
We describe the case of an elderly
woman presenting with
syncope ,
chest pain , electrocardiographic abnormalities , mild enzymatic release , and transient
left ventricular apical ballooning , mimicking an anterior wall
acute coronary syndrome with
shock , following a
subarachnoid haemorrhage that could not be detected upon admission . -
pubmed
METHODS :
Hypersplenism was assessed in 84 consecutive cirrhotic
patients attending a university hospital liver clinic . -
pubmed
RESULTS :
Hypersplenism was present in 78 % of
patients and severe in 39 % . -
pubmed
Severe
hypersplenism was more common in
patients with
cystic fibrosis liver disease ( 88 % , P & lt ; 0.0001 ) and
autoimmune hepatitis ( 60 % , P = 0.0006 ) compared to alcoholic
cirrhosis ( 12 % ) . -
pubmed
There was a significant correlation between
patient age and platelet count r = 0.525 , P & lt ; 0.0001 in the group as a whole and for the sub - group of
patients with
autoimmune hepatitis r = 0.54 , P = 0.047 . -
pubmed
CONCLUSION : Younger
patients had lower platelet counts , larger spleens and a higher incidence of
hypersplenism suggesting that
hypersplenism is significantly related to the age of onset of
chronic liver disease . -
pubmed
High - resolution / high - contrast MRI of
human articular cartilage lesions . -
pubmed
Hiding in the shadows of the HIV epidemic :
obesity and
hypertension in a rural population with very high
HIV prevalence in South Africa . -
pubmed
Structural and quantitative comparison of cerebrospinal fluid glycoproteins in
Alzheimer ' s disease patients and healthy individuals . -
pubmed
A quantitative comparison of gel - separated glycoprotein isoforms from twelve
AD patients and twelve control subjects was performed with glycoprotein - specific and
total protein stains . -
pubmed
We have also compared glycoforms in pooled CSF obtained from
AD patients and control subjects with mass spectrometry . -
pubmed
An outbreak of
chlamydiosis in farmed Indopacific crocodiles (
Crocodylus porosus ) . -
pubmed
An outbreak of
chlamydiosis was diagnosed in hatchling and juvenile Indopacific crocodiles (
Crocodylus porosus ) on a crocodile farm in Papua New Guinea . -
pubmed
This case report discusses an unusual presentation of left
atrial myxoma in an elderly
patient . -
pubmed
Different patterns of neuronal activation and neurodegeneration in the thalamus and cortex of
epilepsy - resistant
Proechimys rats versus
Wistar rats after
pilocarpine - induced protracted
seizures . -
pubmed
PURPOSE : To analyze cellular mechanisms of limbic -
seizure suppression , the response to
pilocarpine - induced
seizures was investigated in cortex and thalamus , comparing
epilepsy - resistant
rats Proechimys guyannensis with
Wistar rats . -
pubmed
METHODS : The trial involved 50 eyes of 48
patients with medically uncontrolled primary and secondary
open - angle glaucoma , randomized to undergo either VDSCI procedure ( 25 eyes ) or DSCI procedure ( 25 eyes ) . -
pubmed
[ Effects of central endocannabinoid system on visceral hyposensitivity induced by rapid eye movement
sleep deprivation : experiment with
rats ] . -
pubmed
Laparoscopic repair of
Morgagni hernia in an adult : use of a
porcine small intestine submucosa biocompatible prosthesis . -
pubmed
We report a case of successful laparoscopic repair of a very large symptomatic
Morgagni hernia in a 78 - year - old patient , treated by positioning a gradually resorbable mesh made from
porcine SIS ( Surgisis Soft Tissue Graft device -- Cook Inc , Bloomington , Ind ) . -
pubmed
METHODS : Observational case report of a
patient who self - inflicted bilateral
scleral lacerations with a razor blade , after losing his job . -
pubmed
RESULTS : The
patient sustained bilateral
inferior scleral perforations , with
hypotony and a right traumatic
cataract . -
pubmed
CONCLUSION : Self - inflicted
ocular injury may be possible in non - psychotic
patients , as a situational response to a life event . -
pubmed
The purpose of this retrospective study was to evaluate the clinical and radiographic results of a curved periacetabular osteotomy for the treatment of
developmental dysplasia of the hip in
patients fifty years of age or older . -
pubmed
METHODS : We evaluated forty - six consecutive hips in forty - two
patients fifty years of age or older ( the older group ) who had
developmental dysplasia of the hip and had undergone a curved periacetabular osteotomy between 1995 and 2006 with a minimum two - year follow - up period . -
pubmed
CONCLUSIONS : Satisfactory results can be obtained clinically and radiographically after curved periacetabular osteotomy in
patients fifty years of age or older with Tonnis grade-1 or 2
osteoarthritis of the hip secondary to
developmental dysplasia . -
pubmed
Is the large size of the pinna of the ear of the
European hare (
Lepus europaeus ) due to its role in thermoregulation or in anterior
capital shock absorption ? -
pubmed
A 68 - year - old
man was admitted with intermittent
chest tightness . -
pubmed
The aim was to evaluate their relative value for the control of ovine
cutaneous myiasis (
sheep blowfly strike ) on farms . -
pubmed
Reliability of ultrasonography to detect
synovitis in
rheumatoid arthritis : a systematic literature review of 35 studies ( 1,415
patients ) . -
pubmed
BACKGROUND :
Osteoporosis is a major healthcare issue with over 50 % of postmenopausal
women suffering an
osteoporosis - related
fracture . -
pubmed
RESULTS : Ninety - six
women had a lateral chest X - ray with 53 ( 55 % ) having
vertebral fractures . -
pubmed
Does objective
shoulder impairment explain
patient - reported functional outcome ? -
pubmed
HYPOTHESIS : Following a healed
proximal humerus fracture ,
patient - reported outcome is predicted by objective physical examination findings . -
pubmed
Hematopoietic stem cell transplantation ( HSCT ) offers the opportunity for cure to
patients with
leukemia ,
lymphoma and severe
non - malignant diseases . -
pubmed
This study indicates that estimating inbreeding
depression might best be based on the performance data of
animals with an equal and sufficiently - large number of ancestral generations known . -
pubmed
Ginseng extracts and
ginsenosides including Rb1 , Rd , Rg1 , Rg3 , Rh1 , Rh2 , Rh3 and Rp1 have been reported to have anti - inflammatory properties in different studies related to
inflammation . -
pubmed
Taken together , this summary provides evidences for the anti - inflammatory effects of
ginseng extracts and
ginsenosides as well as the underlying mechanisms of their effects on
inflammatory diseases . -
pubmed
METHODS : Six
patients with
diffuse peritoneal mesothelioma were treated with 6 cycles of
pemetrexed ( 500 mg / m2 ) and
cisplatin ( 75 mg / m2 ) . -
pubmed
A 10 - year review of all patients treated at a pediatric
burn center was performed with the goal of identifying the characteristics of
patients with
GCMN and the outcomes of the treatment provided in a
burn center . -
pubmed
OBJECTIVE : To determine whether vertebroplasty is more effective than placebo for
patients with
pain of recent onset ( & lt;= 6 weeks ) or severe
pain ( score & gt;= 8 on 0 - 10 numerical rating scale ) . -
pubmed
The membrane bearing the
spots of the synthesized peptides were incubated with the allergic serum pools consisting of the sera from 5
allergic individuals . -
pubmed
baumannii were the common
NFGNB isolated in our study from patients of ,
urinary tract infection ,
bacteremia ,
surgical site infections , and
ventilator associated pneumonia . -
pubmed
METHODS : Data from 52
ulcerative colitis (
UC )
patients with 32
Crohn ' s disease (
CD )
patients were compared . -
pubmed
Primary sclerosing cholangitis (
PSC ) was present in 12/84
patients . -
pubmed
Glucans from the edible mushroom
Pleurotus pulmonarius inhibit
colitis - associated colon carcinogenesis in
mice . -
pubmed
METHODS : In vitro ,
human colorectal cancer cells were treated with FBE and ME and analyzed for
inflammation response , for markers of apoptosis , and for cell - cycle progression . -
pubmed
pulmonarius FBE and ME inhibit
colitis - associated colon
carcinogenesis induced in
mice through the modulation of cell proliferation , induction of apoptosis , and inhibition of
inflammation . -
pubmed
Bisphosphonates combined with
sunitinib may improve the response rate , progression free survival and overall survival of
patients with
bone metastases from
renal cell carcinoma . -
pubmed
We aimed to evaluate whether
bisphosphonates can bring a response rate ( RR ) , progression free survival ( PFS ) and overall survival ( OS ) benefit to
patients with bone
metastasis from
renal cell carcinoma (
RCC ) that is treated with
sunitinib . -
pubmed
METHODS : We performed a multicentre retrospective study of
patients with
bone metastases from
RCC that was treated with
sunitinib . -
pubmed
RESULTS : Between 2004 and 2011 , 209
patients with
metastatic RCC were treated with
sunitinib , 76 had
bone metastases , 35
bisphosphonates users and 41 non - users . -
pubmed
Plasma
sphingosine 1 - phosphate levels and the risk of
vertebral fracture in postmenopausal
women . -
pubmed
PARTICIPANTS : Sixty - nine cases having radiological
VF and 69 age- and
body mass index - matched controls among 460 eligible postmenopausal
women participated in the study . -
pubmed
Dexpramipexole effects on functional decline and survival in
subjects with
amyotrophic lateral sclerosis in a Phase II study : subgroup analysis of demographic and clinical characteristics . -
pubmed
Subjects with
amyotrophic lateral sclerosis (
ALS ) received
dexpramipexole 300 mg / day or 50 mg / day for 24 weeks . -
pubmed
The diagnostic evaluation of a
patient with
dementia . -
pubmed
In
patients aged 80 or older , more than one cause of
dementia is often present , for example ,
Alzheimer disease plus
vascular dementia . -
pubmed
A structured clinical approach helps to define the diagnosis and collects information essential for establishing a comprehensive care plan for
patients with
dementia and their families . -
pubmed
In vivo acquired
daptomycin resistance during treatment of
methicillin - resistant
Staphylococcus aureus endocarditis . -
pubmed
This clinical case reports the emergence of a
daptomycin - resistant
Staphylococcus aureus isolate during
daptomycin treatment in a patient with right - sided
infective endocarditis who had never been treated with
vancomycin . -
pubmed
Moreover , the proposed method was successfully applied to the crude extracts of traditional Chinese medicine and a
marine sponge from which 12 bioactive compounds were screened and characterized based on their anti - oxidative or anti -
tumor activities . -
pubmed
In particular , two
diterpenoid derivatives ,
agelasine B and
( -)- agelasine D , were identified for the first time as anti -
tumor compounds from the sponge
Agelas mauritiana , showing a considerable activity toward
MCF-7 cells ( IC50 values of 7.84 + -0.65 and 10.48 + -0.84 muM , respectively ) . -
pubmed
By experimentally manipulating the intensity of rodent
malaria (
Plasmodium berghei )
infections in
Anopheles stephensi mosquitoes under different environmental conditions , we show that parasites experience substantial density - dependent fitness costs because crowding reduces both parasite proliferation and vector survival . -
pubmed
Finally , the protective effect of intact and EndoS - treated IVIg administered by i.p was studied in a
murine model of progressive
TB . -
pubmed
Although its
neurotoxicity has been extensively described , little is known about its ability to strengthen neural circuits when administered in a manner that reproduces
human abuse ( i.e. -
pubmed
METHODS : From February 2004 to August 2011 , 37 consecutive
patients with symptomatic
hepatic cysts were evaluated and treated at Dong - A University Hospital . -
pubmed
The mean fellow - up was 21 months , and six
patients ( 16 % ) experienced radiographic - apparent
recurrence . -
pubmed
Reoperation due to
recurrence was performed in two
patients . -
pubmed
METHODS :
Patients with
spinal tuberculosis and healthy volunteers were enrolled between December 2004 and December 2010 . -
pubmed
RESULTS : A total of 208
patients with
spinal tuberculosis and 210 healthy
volunteers were included . -
pubmed
Harvesting autologous stem cells from a
patient with red blood cell abnormalities of
beta - thalassemia intermedia . -
pubmed
BACKGROUND : Autologous stem cell transplants in
patients with
hemoglobinopathies are limited . -
pubmed
CONCLUSIONS : Adjustments in apheresis variables allowed successful collection of peripheral blood stem cells from a
patient with RBC anomalies of
beta - thalassemia that interfered with standard stem cell harvesting . -
pubmed
Potential
human immunodeficiency virus transmission makes prompt disclosure of
child sexual abuse in Africa critical . -
pubmed
The number of children reporting child
sexual abuse is increasing , possibly because of increasing awareness , availability of services , and fear of
HIV . -
pubmed
Type 1 diabetes in
mice and men : gene expression profiling to investigate disease pathogenesis . -
pubmed
Using the
nonobese diabetic (
NOD )
mouse model of
T1D and the non - disease prone congenic NOD.B10
mice , our laboratory demonstrated striking tissue - specific and age - dependent changes in gene expression during disease progression . -
pubmed
Remarkably , both genes were also alternatively spliced in the same tissues of auto - antibody positive
prediabetic patients , and these splicing events resulted in similar downstream effects as those seen in
NOD mice . -
pubmed
CONCLUSION : This study suggests that
cinnarizine is safe and effective in reducing both
headache and
vertigo aspects of "
migraine plus
vertigo " among the
patients who suffer from either
vestibular migraine or
migraine with brainstem aura associated with
vertigo . -
pubmed
Toxicity of six plant extracts and two
pyridone alkaloids from
Ricinus communis against the
malaria vector
Anopheles gambiae . -
pubmed
BACKGROUND : The African
malaria vector ,
Anopheles gambiae s.s . -
pubmed
METHODS : We studied by echocardiography and carotid ultrasound 435 asymptomatic
patients with
metabolic syndrome . -
pubmed
Patients with
coronary artery disease or more than mild
valvular heart disease were excluded . -
pubmed
Dengue is an acute
febrile illness caused by any of four mosquito - transmitted
dengue virus (
DENV ) types . -
pubmed
Recent or past
infection with a
DENV was evident in 93 % ( 13 of 14 ) missionaries with available sera . -
pubmed
Polyoxometalates as antitumor agents : Bioactivity of a new
polyoxometalate with
copper on a
human osteosarcoma model . -
pubmed
We report herein for the first time , a detailed study of the mechanisms of action of a
copper ( II ) compound of the group of HPOMs with the formula
K7Na3 [ Cu4 ( H2O ) 2 ( PW9034 ) 2 ] 20H2O (
PW9Cu ) , in a model of
human osteosarcoma derived cell line ,
MG-63 . -
pubmed
METHODS : A total of 40 female
patients diagnosed with
CFS were asked to provide morning saliva
cortisol samples ( after awakening , 30min later , and 1h later ) for seven consecutive days as a measure of
cortisol activity . -
pubmed
In addition ,
patients were exposed to the Trier Social Stress Test , a well - validated stress test , to investigate the relationship between early childhood
trauma and
cortisol stress reactivity . -
pubmed
Extracorporeal membrane oxygenation ( ECMO ) may be used to support
patients with severe
hypoxemic respiratory failure refractory to conventional mechanical ventilation . -
pubmed
We describe our center 's experience with four
patients who received ECMO for refractory
hypoxemic respiratory failure due to
diffuse alveolar hemorrhage (
DAH ) , a condition for which anticoagulation is typically contraindicated , and provide a review of the literature . -
pubmed
The results from this case series , along with previously published data , suggest that ECMO is a reasonable management option for
patients with DAH - associated severe , refractory
hypoxemic respiratory failure . -
pubmed
UNLABELLED : Specific types of
human papillomavirus (
HPV ) are strongly associated with the development of
cervical carcinoma . -
pubmed
These findings shed light on the mechanisms by which
HPV induces
genomic instability and hold promise for the identification of drug targets . -
pubmed
These findings shed light on the mechanisms by which
HPV induces
genomic instability and hold promise for the identification of drug targets . -
pubmed
Initial therapies for newly diagnosed
myeloma patients depend on the individual 's clinical condition . -
pubmed
Induction therapy with novel agents and high - dose chemotherapy followed by autologous stem cell transplantation is a standard therapy for newly diagnosed younger
myeloma patients . -
pubmed
are widely used as initial therapy for transplantation - ineligible
myeloma patients . -
pubmed
RESULTS : Primary outcome was surgical site
infection (
SSI ) , and 142
patients were included . -
pubmed
The
SSI occurred in 22 % of
patients in group 1 and in 29 % of
patients in group 2 ( P = .39 ; odds ratio : 1.46 confidence interval 95 % : 0.61 - 3.47 ) . -
pubmed
We followed up 19,825
patients who survived a first admission for
stroke at the age of & gt;= 18 years , among which 3,536 hospitalized cases with
stroke recurrence ( ICD-9 - CM codes 430.xx-437.xx ) were identified and individually matched to 6,679 randomly - selected controls . -
pubmed
MATERIALS AND METHODS : We retrospectively reviewed 837
patients who underwent RARP for clinically localized
prostate cancer without neoadjuvant endocrine therapy . -
pubmed
A total of 4 species were identified among the MRCoNS isolates , namely ,
Staphylococcus sciuri ( 10
strains ) ,
Staphylococcus lentus ( 6
strains ) ,
Staphylococcus cohnii ( 3
strains ) and
Staphylococcus haemolyticus ( one
strain ) . -
pubmed
Overall ,
patients with
CKD had higher FRS risk score ( 25.9 % vs 20 % , p = 0.001 ) and more
CVD events ( 22.3 % vs 11.9 % , p = 0.002 ) over a 10 - year period compared to patients without
CKD . -
pubmed
PURPOSE : To report a case of
canine atypical
chorioretinal coloboma where ophthalmoscopic , fluoroangiographic and optical coherence tomography characteristics are described . -
pubmed
ANIMAL STUDIED : A 2 - year - old Golden Retriever
dog in which routine ophthalmoscopic examination allowed diagnosis of a
posterior coloboma on the left eye . -
pubmed
CONCLUSIONS : Fluoroangiographic and optical coherence tomographic studies of an atypical
chorioretinal coloboma in a
dog are reported for the first time . -
pubmed
Our study provided no direct support for high - concentration inspired
oxygen in reducing the incidence of
SSIs in
patients undergoing all types of surgery . -
pubmed
The methanolic extract revealed antioxidant activity and did not show
hepatoxicity in
porcine liver primary cells . -
pubmed
SUBJECTS :
Patients with histologically confirmed
acute appendicitis . -
pubmed
RESULTS : A total of 130
patients who had appendicectomy for
acute appendicitis were included in the study . -
pubmed
All the
patients presented with
right iliac fossa pain and
tenderness . -
pubmed
OCD typically arises in
youth but delays in diagnosis impede optimal treatment and developmental studies of the disorder . -
pubmed
KO
mice exhibit compulsive self - grooming behavior analogous to behaviors found in
people with
OCRD . -
pubmed
Striatal
hyperactivity has been reported in these
mice and in
humans with
OCD . -
pubmed
At the age range studied , only 1 of 8 KO
mice had
skin lesions indicative of severe
compulsive grooming . -
pubmed
Anticancer activity of an ultrasonic nanoemulsion formulation of
Nigella sativa L. essential oil on
human breast cancer cells . -
pubmed
PURPOSE OF REVIEW :
Legionella pneumophila is a facultative intracellular pathogen and an important cause of community - acquired and
nosocomial pneumonia . -
pubmed
OBJECTIVE : To evaluate and describe the sleep quality in seven subscales among the
patients with
mild traumatic brain injury (
TBI ) and compare it with normal patterns . -
pubmed
RESULTS : Overall we included 60
patients with mild
TBI with mean age of 36.2 + -13.4 years . -
pubmed
All the
patients had
sleep disturbance . -
pubmed
CONCLUSION :
Patients with mild
TBI have poor sleep quality which should be considered as one of the main factors in interventions after the
injury and it might lead to better quality of life . -
pubmed
We report a rare case of bilateral
pneumothoraces resulting from tracheostomy in an advanced
laryngeal cancer patient . -
pubmed
A 59 - year - old
man was referred to our clinic for evaluation and treatment of
laryngeal tumor . -
pubmed
Primary
optic nerve sheath meningiomas (
PONSM ) are rare in
children . -
pubmed
A 5 - year - old
girl presented with
visual impairment and
proptosis . -
pubmed
Prospective randomized evaluation of the watchman left atrial appendage closure device in
patients with
atrial fibrillation versus long - term
warfarin therapy : The PREVAIL trial . -
pubmed
OBJECTIVES : Assessing the safety and effectiveness of left atrial appendage ( LAA ) ( pouch found in the upper chambers of the heart ) occlusion , using the Watchman device compared to long term
warfarin therapy ( drug that reduces clot formation ) , in preventing the risk of
stroke in
patients with
atrial fibrillation ( most common type of
irregular heart beat ) . -
pubmed
METHOD :
Patients with
atrial fibrillation and at high risk of
stroke were randomly allocated a group after they were deemed eligible . -
pubmed
CONCLUSION :
LAA occlusion is a reasonable alternative to chronic
warfarin therapy in
stroke prevention for
patients with
atrial fibrillation . -
pubmed
Sleep problems in
children with
dyslexia : understanding the role of sleep in neurocognitive development through the lens of
developmental disorders . -
pubmed
Eculizumab is a safe and effective treatment in pediatric
patients with atypical
hemolytic uremic syndrome . -
pubmed
The current role of MEG for presurgical evaluation with regard to noninvasive localization in MRI normal
patients , guiding of invasive electrode implantation and correlation to postoperative outcome after
epilepsy surgery is stressed . -
pubmed
SCOPE :
Chicory inulin is a naturally occurring fructan that is conducive to
glucose and lipid metabolism in
patients with
diabetes mellitus . -
pubmed
This study aims to investigate the mechanism by which
chicory inulin improves glucolipid metabolism in
diabetic conditions . -
pubmed
METHODS AND RESULTS :
Rats were injected with
streptozotocin and fed with high fat diet to induce
diabetes , and then administrated with different doses of
chicory inulin for 8 weeks . -
pubmed
Randomized , controlled trials of restrictive RBC transfusion practices have shown equivalent
patient outcomes compared with liberal transfusion practices , and meta - analyses have shown improved in - hospital mortality , reduced cardiac events , and reduced
bacterial infections . -
pubmed
The suitability of using a spore - forming ureolytic
strain ,
Bacillus sphaericus , was evaluated for self - healing of concrete cracks . -
pubmed
Presently described is lichenoid type
cutaneous hyperpigmentation in a 46 - year - old female
patient . -
pubmed
Diabetic retinopathy (
DR ) affects over 93million
people worldwide and is the number one cause of
blindness among working age adults . -
pubmed
METHOD : We reviewed preoperative and postoperative records of
patients undergoing surgery for
pituitary adenomas . -
pubmed
RESULTS : Of 394
patients included for analysis , 29 cases ( 7.4 % ) fulfilled criteria for
atypia . -
pubmed
Patients with atypical
tumours were significantly younger than those with typical
adenomas . -
pubmed
CONCLUSIONS :
Patients with atypical non - functional
pituitary adenomas are at risk for postoperative
recurrence and
disease progression , suggesting a need for adjuvant therapy . -
pubmed
An important challenge to using
fluorodeoxyglucose - positron emission tomography (
FDG - PET ) in clinical trials of
brain tumor patients is to identify malignant regions whose metabolic activity shows significant changes between pretreatment and a posttreatment scans in the presence of high normal brain background metabolism . -
pubmed
INTRODUCTION : although the outcome for
patients with
rheumatoid arthritis ( ra ) has improved in the past decades , adequate disease control can not be achieved in a substantial proportion of
patients . -
pubmed
Furthermore , the article summarizes and comments the drug 's efficacy and safety profile in
RA patients . -
pubmed
C57BL/6J wild type
mice in post -
MI were inoculated with P.g . -
pubmed
Plasma samples and twelve tissue samples from
mice hearts after
MI were obtained . -
pubmed
METHODS : We retrospectively enrolled 14
patients with
CADM - associated
RPIPs and acute
respiratory failure treated with
PMX - DHP ,
corticosteroids , and immunosuppressive agents . -
pubmed
The association with
penile cancer , in particular
non - invasive disease , and
human papilloma virus (
HPV ) is well known . -
pubmed
In vivo antimicrobial experiment with a
rat subcutaneous model indicates the
catechol - chitosan film at reduced state inhibits the bacterial growth and alleviates the
infection of the incisions . -
pubmed
Open
wound healing tests with a
mouse model indicate that the
catechol - chitosan film suppresses the bacterial population at the
wound site , induces less
inflammation and promotes
wound healing . -
pubmed
Streptococcus Anginosus Group - associated
Pyogenic Liver Abscess . -
pubmed
General inclusion criteria included English - language randomised
human trials reporting the use of
ozone therapy in the topical treatment of
chronic wounds . -
pubmed
Leprosy is a
chronic intracellular infection caused by the acid - fast bacillus ,
Mycobacterium leprae . -
pubmed
Studying these important components of the adaptive immune system in
leprosy patients is essential for better understanding of immune function , correlate(s ) the immunity and mechanism(s ) of its containment . -
pubmed
METHODS : We created four groups according to sex and
anxiety symptomatology : high -
anxiety girls ( n = 24 ) and
boys ( n = 25 ) , and low -
anxiety girls ( n = 22 ) and
boys ( n = 24 ) and recorded their cardiac function while they performed regular school activities . -
pubmed
Medication adherence in
patients with
schizophrenia : a qualitative study of the
patient process in motivational interviewing . -
pubmed
Human brown adipose tissue : Underestimated target in
metabolic disease ? -
pubmed
Methods : Between March 2012 and December 2016 , 20
patients ( 21 lesions ) with benign
bone tumors or
tumor like conditions of proximal femurs were treated with DHS and intralesional curettage via Watson - Jones approach . -
pubmed
The time of full weight - bearing was 2 days in 2
patients with
giant cell tumor and 2 to 13 weeks with an average of 7.2 weeks in the other
patients . -
pubmed
Discontinuation of hormone therapy for elderly
breast cancer patients after hypofractionated whole - breast radiotherapy . -
pubmed
Bacterial
spot caused by
Xanthomonas perforans causes significant damage on
tomato in Florida . -
pubmed
Inductively coupled plasma mass spectrometric analysis of the fruit confirmed that Nano -
MgO application did not lead to the accumulation of
Mg ,
Cu ,
Ca , K ,
Mn , P , and
S. This study is the first to demonstrate the potential of Nano -
MgO against bacterial
spot of
tomato . -
pubmed
[ Ningmitai Capsules relieve
lower urinary tract symptoms in
patients with
benign prostatic hyperplasia : A short - term clinical observation ] . -
pubmed
Objective : To observe the clinical effect and safety of the Chinese patent medicine Ningmitai Capsules ( NMT ) in relieving
lower urinary tract symptoms (
LUTS ) in the
patient with
benign prostatic hyperplasia (
BPH ) . -
pubmed
METHODS : We randomly assigned 40
BPH patients to an experimental and a control group of equal number to receive oral administration of
NMT at 4 capsules tid and
terazosin hydrochloride tablets at 2 mg qd , respectively , both for 14 days . -
pubmed
CONCLUSIONS :
NMT is safe and effective in relieving
LUTS in
BPH patients . -
pubmed
RESULTS : Compared with the control group , the final
body weight and body
weight gain were significantly higher in HFD - fed
rats , while the testicle /
body weight ratios were lower ( P & lt ; 0.05 ) . -
pubmed
Treatment with
4 - PBA attenuated HFD - induced histological damage , ameliorated the HFD - induced decrease in serum
testosterone ( T ) , and reduced the rate of testicular cell apoptosis ( P & lt ; 0.05 ) in
obese male rats . -
pubmed
Liver mitochondrial respiratory plasticity and
oxygen uptake evoked by
cobalt chloride in
rats with low and high resistance to extreme hypobaric
hypoxia . -
pubmed
We determined the
cobalt chloride (
CoCl2 ) effects on liver mitochondrial plasticity and
oxygen uptake in
rats with low resistance ( LR ) and high resistance ( HR ) to extreme hypobaric
hypoxia . -
pubmed
We have unveiled several mechanisms leading to differentiated mitochondrial respiratory responses to hypobaric
hypoxia in LR and HR
rats . -
pubmed
These results are particularly relevant once sprouted and fermented
quinoa could be an alimentary source of interest , especially for disease risk prevention such as
diabetes ,
obesity and
dyslipidemias . -
pubmed
This case reports a very rare case of
IgG4 - RD presenting with a
cutaneous lesion in a young female
patient mimicking a
lymphoproliferative disorder . -
pubmed
OBJECTIVE : To evaluate the efficacy and clinical results of full endoscopic debridement and drainage ( FEDD ) for high - risk
patients with
spondylodiscitis . -
pubmed
All
patients had single - level
infectious spondylodiscitis and were high - risk candidates for surgery . -
pubmed
RESULTS : All 14
patients experienced immediate relief of
back pain after FEDD , with no procedure - related complications . -
pubmed
CONCLUSIONS : FEDD may be an effective alternative to extensive open surgery in
patients with
infectious spondylodiscitis , especially those who are high - risk candidates for surgery ( elderly patients with multiple comorbidities and patients in poor general condition ) . -
pubmed
Nevertheless , the margin width remains controversial particularly in
cirrhotic patients where optimal parenchymal preservation is necessary . -
pubmed
Totally , 534
patients who received liver resection for
HCC were included . -
pubmed
The clinical profiles of the
patients ,
tumor characteristics and
patients ' survival were all collected . -
pubmed
Most of the
patients had
hepatitis B ( 52.4 % ) and
hepatitis C ( 24.0 % )
infection . -
pubmed
BACKGROUND : :
Tremor is present in almost half of
multiple sclerosis (
MS )
patients . -
pubmed
OBJECTIVES : : To clarify the structural and functional brain changes associated with the clinical phenotype of
upper limb tremor in
people with
MS . -
pubmed
METHODS : : Fifteen healthy
controls ( 46.1 + - 15.4 years ) , 27
MS participants without
tremor ( 46.7 + - 11.6 years ) and 42 with
tremor ( 46.6 + - 11.5 years ) were included . -
pubmed
RESULTS : :
Tremor participants were found to have
atrophy of the cerebellum and thalamus , and higher ipsilateral cerebellar lesion load compared to participants without
tremor ( p & lt ; 0.020 ) . -
pubmed
Introduction : The polyomaviruses , John Cunningham ( JC ) and BK , infect
humans , with
primary infection occurring in childhood . -
pubmed
The absence of
John Cunningham virus (
JCV ) , DNA was a strong predictor of
CKD ( odds ratio [ OR ] 43.43 ; 95 % confidence interval [ CI ] 7.39 - 255.20 ; P & lt ; 0.001 ) . -
pubmed
Longer Control of Nivolumab in
Metastatic Renal Cell Carcinoma Patients with
End - Stage Kidney Disease on Dialysis . -
pubmed
However , despite widespread evidence of its utility , few reports have described the efficacy of
nivolumab for
mRCC patients on hemodialysis . -
pubmed
Case Presentation : A 68 - year - old
man with a 20 - year history of dialysis due to
chronic glomerulotubular nephritis was referred to our department for
bilateral renal tumors in 2015 . -
pubmed
Conclusion : We herein report a
patient with
RCC on hemodialysis with long - term
cancer control by
nivolumab . -
pubmed
[ Allogeneic stem cell transplantation in elderly
patients with
acute myeloid leukemia ] . -
pubmed
Acute myeloid leukemia is a disease that mainly affects older populations , with a median age at diagnosis of 67 years , and outcomes for these
patients are poor . -
pubmed
We concluded that active cardiac assessment is a prudent step in
patients presenting with
sarcoidosis regardless of the organ of affectation at presentation or diagnosis . -
pubmed
METHODS : Fifty
patients with fan - shaped displacement of anterior teeth caused by
periodontitis in PLA air force hospital from January 2013 to October 2018 were selected and randomly divided into the control group ( n=25 ) and the experimental group ( n=25 ) . -
pubmed
The symptoms of
periodontitis can be effectively improved , the teeth can be effectively corrected and facial profiles of the
patients can be improved . -
pubmed
Correlation study between the pharmacokinetics of seven main active ingredients of
Mahuang decoction and its pharmacodynamics in
asthmatic rats . -
pubmed
To illustrate our arguments , we refer to the extent of regional cooperation for health in ASEAN and the EU for ( re)emerging
infectious disease control and for
tobacco control . -
pubmed
While not all investigations observe a beneficial effect of these compounds , there are multiple studies that show a protective effect of each of these lifespan - extending compounds in
animal models of
neurodegenerative disease . -
pubmed
BACKGROUND : Modern chemotherapeutics have led to improved systemic disease control for
patients with locally advanced
pancreatic cancer ( LAPC ) . -
pubmed
Hypogonadism and bone health in men with
HIV . -
pubmed
The advent of new classes of antiretroviral drugs has improved the survival of people with
HIV , and several ageing - related conditions , including
hypogonadism and
osteoporosis , have emerged . -
pubmed
BACKGROUND : The aim of this study was to evaluate the cardio - metabolic risk in
schizophrenia patients treated by atypical antipsychotic drugs compared with that in those treated without atypical antipsychotic drugs using a nationwide insurance claims database and medical examination database in Japan . -
pubmed
METHODS : Eligible
patients were defined as those meeting the following two criteria : ( i ) A diagnosis of
schizophrenia ( ICD-10 code : F20 ) was made between 1 January 2005 and 31 December 2017 , with data available for at least 6 months before the diagnosis was made ( index month ) , and ( ii ) health check - up data were available within + -3 months of the index month . -
pubmed
Patients receiving atypical antipsychotic drugs exhibited a greater change in the Suita score and a risk of
coronary heart disease based on the Suita score of 0.530 and 0.098 % , respectively , than
patients not receiving atypical antipsychotic drugs , but there was no significant difference ( p = 0.412 and 0.610 ) . -
pubmed
Proximal intestinal obstruction syndrome (
PIOS ) in a
patient with
cystic fibrosis : A case report . -
pubmed
Presentation of case : We report a case of a 45 years old
patient with
cystic fibrosis , who presented
bowel obstruction secondary to accumulation of fecal material , combined with mucous secretions , in the mid - jejunum . -
pubmed
Discussion : We present a case of a
patient with
cystic fibrosis presenting with
bowel obstruction due to a
proximal intestinal obstruction syndrome , which can be diagnosed with the DIOS definition , with the only distinction of a more proximal location in the gastrointestinal tract , such as the stomach , the duodenum , or the jejunum . -
pubmed
The effects of miR-30a-3p overexpression on the proliferation and apoptosis as well as oxidative stress
injury were evaluated in
rats RA - FLS . -
pubmed
Further investigation indicated that miR-30a-3p agomir exerted anti - arthritic effects on adjuvant - induced
arthritis (
AA ) in
rats . -
pubmed
[ Osteoprotective effect of bread enriched with protein , dietary fiber ,
calcium ,
iron and
iodine in hypoestrogen - induced
osteoporosis among
rats ] . -
pubmed
The aim was to study the effect of bread enriched with protein , dietary fiber ,
calcium ,
iron and
iodine on the state of the bone tissue of
rats in a model of
postmenopausal osteoporosis . -
pubmed
The experiment was performed on sexually mature female
Wistar rats divided into groups : K - control ( sham - operated
rats , not ovariectomized ) ; O30 -
osteoporosis model ( animals were sacrificed 30 days after ovariectomy ) ; groups O120 and O120 + - a model of
osteoporosis (
rats were sacrificed 120 days after ovariectomy ) . -
pubmed
For
rats of the O120 + group , from the 40th to the 120th day , enriched bread was included in the diet in an amount of 6 g per 100 g of
body weight per day . -
pubmed
The micro - architectural structure of the femur in the O120 + group of
rats was close to that of the O30 sample , which serves as a model of the early stage of
osteoporosis (
SMI 1.42 + -0.07 ; TbPf 5.55 + -0.28 1 / mm ) . -
pubmed
Bread enriched with protein , fiber ,
calcium ,
iron and
iodine , effectively weakens
osteoporosis induced by ovariectomy in
rats . -
pubmed
METHODS : Our internal registry was used to identify all
patients who received surgical treatment of an
acl tear during childhood and adolescence by transepiphyseal acl reconstruction more than 15 years previously . -
pubmed
None of the included
patients showed a
growth disorder during the course of the study . -
pubmed
In 92 % of
patients , an intact acl reconstruction was found without evidence of
cartilage or meniscus damage . -
pubmed
These were compared with adult normal
mouse lung and lungs of the
animals treated with
4 - nitroquinoline 1 - oxide at a monthly interval until
cancer developed . -
pubmed
Catecholamine levels in discrete brain nuclei of seven month old genetically
obese rats . -
pubmed
Muco - cutaneous leishmaniasis : intradermal test with a promastigote suspension and a crude extract from
Leishmania braziliensis . -
pubmed
We tried this catheter for 11 various urological
patients who needed a long - term indwelling of a balloon catheter for lower
urinary tract obstruction and
neurogenic bladder . -
pubmed
All
patients were already indwelled
silicon balloon catheter for 3 to 6 months and suffered with complicated
urinary tract infection . -
pubmed
Two
patients ( 22.2 % ) showed good results by the
urinary tract infection (
UTI ) criteria and 5 patients ( 55.4 % ) showed good effects by doctor 's judgment . -
pubmed
A randomized controlled trial was performed to study the efficiency of adjuvant chemotherapy with early intravesical instillation of
Adriamycin and long - term oral administration of
5 - fluorouracil in 275
patients with superficial
bladder cancer . -
pubmed
To clarify the existence of the vertical component during a
caloric nystagmus and the existence of a second phase of the
nystagmus , 194 induced incidents of a
caloric nystagmus in 29 normal
subjects have been analyzed . -
pubmed
An immunocorrective effect of current methods of detoxication in experimental acute destructive
pancreatitis was studied on 40 mongrel male
dogs with body mass 13 - 15 kg . -
pubmed
Following 6 h of left
middle cerebral artery occlusion ,
rat brains were frozen in situ . -
pubmed
To address these issues , we reviewed the clinicopathologic and immunohistochemical features of 22 cases ( 11
men and 11
women ; mean age , 56 years ) of
laryngeal amyloidosis . -
pubmed
Six
patients had concomitant
tracheal amyloidosis . -
pubmed
Ten
patients underwent repeated operations for persistent or recurrent
respiratory tract disease . -
pubmed
One
patient died of progressive
tracheobronchial amyloidosis , but
systemic amyloidosis did not develop in any of the
patients . -
pubmed
[ The immunological rehabilitation of
patients with chronic
nonspecific lung diseases at sanatoria and health resorts ] . -
pubmed
Histoplasmosis relapse in patients with
AIDS : detection using
Histoplasma capsulatum variety capsulatum antigen levels . -
pubmed
OBJECTIVE : To assess the accuracy of
Histoplasma capsulatum variety capsulatum polysaccharide antigen testing for the identification of
histoplasmosis relapse in patients with the
acquired immunodeficiency syndrome (
AIDS ) . -
pubmed
PATIENTS : Twenty episodes of
histoplasmosis relapse were evaluated in 17
patients with
AIDS from November 1987 to August 1990 . -
pubmed
Controls included 30
patients with
AIDS and
histoplasmosis who did not have a
relapse during maintenance therapy and who were initially tested during the same week as the
patients with
relapse . -
pubmed
A second control group included seven
patients with
AIDS and
histoplasmosis who were evaluated for
relapse on 23 occasions ;
relapse , however , was excluded on each occasion . -
pubmed
MAIN RESULTS : For the 20 episodes of
relapse ( 17
patients ) ,
H.c . - pubmed
Forty
patients underwent pancreaticoduodenectomy for
malignant disease in a 25 - year review of 6 Portland - area hospitals . -
pubmed
One hundred and eighteen
patients with acute unilateral
sensorineural hearing loss were examined . -
pubmed
Serological tests were performed including influenza- , parainfluenza- , adenovirus- ,
RS - virus , enterovirus- , morbilli- , varicella- and cytomegalie - virus - KBR , also the serological tests for
toxoplasmosis ,
rheuma , lues ,
mycosis , and
Borrelia . -
pubmed
The cardiovascular responses of
rats of different ages , ranging from 4 - 15 weeks (
body weight 115 - 490 g ) , to acute left coronary artery ligation under
pentobarbitone anaesthesia were studied . -
pubmed
In older
animals , the responses included the occurrence of
ventricular tachycardia and/or
fibrillation , decrease in blood pressure , and a slight increase in heart rate . -
pubmed
On the contrary , younger
rats exhibited
atrioventricular block followed by
ventricular arrest , and decreases in both blood pressure and heart rate . -
pubmed
The findings demonstrate the existence of age - related cardiovascular responses to acute
myocardial ischaemia in
rats , and suggest that 10 - 15 - week - old male
Sprague - Dawley rats are suitable experimental
animals for producing early
ventricular arrhythmias by acute coronary artery ligation . -
pubmed
88 % of the
patients showed a considerable improvement : 69 % were free from
arrhythmias and 33 % exhibited a significant reduction . -
pubmed
Influence of
hypercholesterolemia and
cholesterol accumulation on
rabbit carrageenan
granuloma macrophage activation . -
pubmed
These experiments were designed to determine whether
hypercholesterolemia and the accumulation of
cholesterol or
cholesteryl esters in
rabbit carrageenan
granuloma macrophages might influence selected markers of macrophage activation . -
pubmed
Granulomas induced by subcutaneous injection of carrageenan into
rabbits were harvested after 4 , 14 , and 28 days . -
pubmed
Increasing exposure of the elderly to pharmacologic agents that reduce
CH2O is primarily responsible for the impression that aged
patients are at increased risk for
hyponatremia . -
pubmed
A commercial enzyme - linked immunosorbent assay ( ELISA ) to detect serological response to vaccination and virulent challenge with type 1 ( X-73 )
Pasteurella multocida was used to determine the best vaccination protocol for broiler breeders against
fowl cholera . -
pubmed
Sixty - five
patients with histologically proven
chronic active hepatitis of unknown cause but associated with the antiliver / kidney microsome antibody type 1 , confirmed by immunofluorescence and immunoprecipitation , were selected as forming a special entity . -
pubmed
The clinical course was usually severe : six
patients in the acute stage presented with
fulminant hepatitis , and all , except two , other
patients progressed to
cirrhosis . -
pubmed
The incidence of side effects is generally low , but in the elderly and in
patients with
renal or hepatic failure , both of these drugs can produce
confusional states . -
pubmed
Proteins ,
animal fats , disugars and products of animal origin , refined products and daily energy content of rations were shown to be directly related to
CHD morbidity ( 0.61 - 0.94 ) ,
arteriosclerosis ( 0.70 - 0.96 ) ,
myocardial infarction and
cardiosclerosis ( 0.67 - 0.96 ) mortality , their association with
hypertension being reverse ( -0.66 - 0.80 ) . -
pubmed
Vegetable fats , starch , cellulose , hemicellulose , pectin , buns and rolls ,
vegetables and fruit showed reverse correlation with
CHD morbidity ( -0.53 - 0.88 ) as well as with
arteriosclerosis ( -0.57 - 0.95 ) ,
myocardial infarction and
cardiosclerosis ( -0.61 - 0.96 ) mortality . -
pubmed
Anaphylactic release of
histamine from
guinea pig skin in vitro . -
pubmed
Pulmonary nodule caused by a living
Brugia malayi - like filaria in an artery . -
pubmed
[ The effect of
DDT poisoning on the quantity and swelling of mitochondria of wing musculature isolated from susceptible and resistant flies
Musca domestica L ] . -
pubmed
As a compensatory mechanism in approximately one third of
patients with
palatopharyngeal insufficiency , the superior constrictor muscle may be active in the form of Passavant 's ridge . -
pubmed
Seven
children with
Crohn ' s disease and
linear growth retardation were studied in order to determine the best method of treating this psychologically debilitating complication . -
pubmed
[ Therapeutic criteria for the use of
nifedipine in
patients with
chronic aortic insufficiency ] . -
pubmed
Neurotransmitters in the treatment of
patients with severe
head injuries . -
pubmed
Results of treatment with
L - dopa and/or
physostigmine of
patients with severe
head injuries were examined and discussed . -
pubmed
This treatment given to
patients still unconscious a long period after
trauma resulted in clinical improvement in 29 of the 45 trials ( 64 % ) . -
pubmed
The metabolism of
mevalonate was studied in 6
dog kidneys and in 5
human tumour - involved kidneys during 6 days of hypothermic perfusion . -
pubmed
A
patient with severe , penetrating
brain injury is presented . -
pubmed
The
patient was in psychiatric treatment for four years , starting two months after the
injury ; psychological tests were administered four times . -
pubmed
A
strain of Streptomyces , isolated from a soild sample and identified as
Streptomyces unzenensis sp . - pubmed
Local cerebral blood flow after
middle cerebral artery occlusion in
rabbits following transposition of omentum to the brain . -
pubmed
Transposition of pedicled omental grafts to the brain has been shown to minimize the effects of
cerebral infarction in
dogs and
monkeys . -
pubmed
Strain- and sex - linked effects of dietary
polyunsaturated fatty acids on
tumor growth and immune functions in
mice . -
pubmed
In the present paper , we studied the influence of different levels of dietary
polyunsaturated fatty acids (
PUFA ) on the immune system and
tumor growth in young
mice . -
pubmed
Female
BALB / c mice fed a
PUFA - rich diet display an enhanced body growth , proliferative response to mitogens in vitro , and rate of growth of a spontaneous transplantable
adenocarcinoma as compared to
PUFA - poor diet - fed females . -
pubmed
Moreover , in female DBA/2
mice with the same haplotype ( H-2d ) of the major histocompatibility complex as that of BALB / c
mice , low dietary
PUFA determines a reduced
tumor growth only , but it does not affect body growth and proliferative response to mitogens in vitro . -
pubmed
Cytotoxicity and DNA cross - linking activity of
4 - sulfidocyclophosphamides in
mouse leukemia cells in vitro . -
pubmed
Binary combinations of pure chemicals and complex mixtures were evaluated for their ability to produce additive
mutagenicity responses in the spiral and standard
Salmonella mutagenicity assays . -
pubmed
The purpose of the work was an assessment of the usefulness of transcutaneous measurement of
O2 pressure in the foot ( in recumbent position , recumbent with venostasis , elevated and erect position ) for the detection of microcirculation disturbances in
patients with
diabetes mellitus . -
pubmed
The studies included 43
patients with
type I and II diabetes without haemodynamically significant stenoses of the axial arteries of the lower limbs , and a control group of 14 . -
pubmed
It was found that already in the period preceding the development of obliterative lesions in the arteries , microcirculation disturbances in the lower limbs became manifest causing statistically significant decrease of tcPO2 in
patients with
type I and II diabetes mellitus . -
pubmed
We describe a
patient with
systemic mastocytosis associated with
chronic myelomonocytic leukemia accompanied by
ascites ,
pleural effusion , and development of
skin lesions along a surgical scar . -
pubmed
To evaluate the role of platelets in
patients with
sepsis and
MOF , we examined changes in surface glycoproteins on circulating platelets of 14
patients with suspected
sepsis and
MOF . -
pubmed
Since mental practice in healthy
people leads to central nervous activation processes as well as to an improvement of motor skills , we investigated the effects of mental practice alone on central nervous activity by means of EEG in
stroke patients . -
pubmed
Twelve left - sided
hemiplegic patients who underwent a specific poststroke rehabilitation treatment were requested to perform a simple arm movement sequence . -
pubmed
In tall animals dependent tissues are stiffer to prevent
oedema formation in the upright posture , but whether the same adaptation is operating in
man is not known . -
pubmed
New
benzo [ a ] naphthacenequinone metabolites , designated
bequinostatins A and B , have been isolated from the culture broth of the
benastatin - producing
strain Streptomyces sp . - pubmed
Cerebellar ataxia ,
meningitis and
cerebral infarction were found in young
children under 9 years , and other disorders were seen also in older children and adults . -
pubmed
In our 4 cases of
herpes zoster meningitis , marked intrathecal
VZV - specific antibody production was found and they showed high antibody index . -
pubmed
Morning variations of plasma
homovanillic acid in untreated
schizophrenic patients . -
pubmed
Plasma concentrations of
homovanillic acid were determined in samples obtained at 8.30 a.m. and 12.30 p.m. from 29 untreated
schizophrenic patients , 14
males and 15 females . -
pubmed
Genotoxicity studies of
quercetin and
shikimate in vivo in the bone marrow of
mice and gastric mucosal cells of
rats . -
pubmed
Bracken fern (
Pteridium aquilinum ) causes
acute and chronic toxicity in animals and is associated with a high incidence of
stomach and esophageal tumors in
humans in countries where it is consumed as food , yet the toxic constituent(s ) has not been unequivocally identified . -
pubmed
The
carcinogenicity of the
plant has at one time or another been attributed to
quercetin ,
shikimate or
ptaquiloside . -
pubmed
Studies to determine whether or not the
genotoxicity of
quercetin ,
shikimate ( and its metabolite
cyclohexane - carboxylate ) could be enhanced in combined application were conducted in vivo using the micronucleus test in
mice and the unscheduled DNA synthesis in
rat gastric mucosal cells . -
pubmed
Effects of
nordihydroguaiaretic acid on
murine antibody - dependent cellular
cytotoxicity . -
pubmed
Antibody - dependent cellular
cytotoxicity mediated by
murine spleen cells was significantly inhibited by concentrations of
nordihydroguaiaretic acid from 10(-5 ) to 10(-4 ) M ( 1C50 = 2 x 10(-5 ) M ) . -
pubmed
These results suggest that
arachidonic acid metabolites other than
leukotriene B4 are released by different populations of spleen cells to positively regulate important events in the postbinding phase of
murine antibody - dependent cellular
cytotoxicity . -
pubmed
We report three
patients who were operated on because of an intraabdominal
schwannoma between February 1991 and October 1994 in our department . -
pubmed
Eleven
dogs were exercised on a treadmill at 3 km / hr for 75 minutes 5 days a week for 527 weeks while carrying jackets weighing 130 % of their
body weight . -
pubmed
These results show that a lifetime of regular weightbearing exercise in
dogs with normal joints did not cause alterations in the structure and mechanical properties of articular cartilage that might lead to
joint degeneration . -
pubmed
An analysis of 676 consecutive prostatectomies revealed that 4.3 % of the
men had
tumor touching the inked bladder neck margin . -
pubmed
A 52 - year - old
man with a history of
portal hypertension was intubated emergently for airway protection because of
respiratory insufficiency due to
sepsis . -
pubmed
At the conclusion of the procedure , the
patient sustained large volume
hematemesis due to esophageal variceal
rupture . -
pubmed
This case report provides strong evidence in support of administering
fentanyl , or a suitable alternative adjunctive medication , before intubation of
patients with documented portal
hypertension and a history of
esophageal variceal hemorrhage . -
pubmed
PURPOSE OF STUDY : To establish a diagnosis and therapeutic management in
patients with
extramedullar plasmocytomas . -
pubmed
One
patient with a
nasal cavity tumor location and a review of literature are reported . -
pubmed
Phase II trial of weekly intravenous
gemcitabine with continuous infusion
fluorouracil in
patients with
metastatic renal cell cancer . -
pubmed
Patients had a
Cancer and
Leukemia Group B performance status of 0 or 1 , with a median time since diagnosis of metastatic
disease of 10 months ( range , 0 to 129 months ) . -
pubmed
CONCLUSION : Weekly
gemcitabine with continuous infusion
5 - FU is an active combination in
patients with
metastatic RCC . -
pubmed
Significant abnormality (
stenosis & gt ; 70 % or occlusion ) was found in 20 % of the
patients . -
pubmed
Class Ic drugs are not advisable for
patients with structural
cardiac abnormalities secondary to a high risk of
proarrhythmia . -
pubmed
The risk of
proarrhythmia is increased in
patients with abnormal cardiac substrate , with
electrolyte abnormalities , and during drug initiation . -
pubmed
We estimated U and sh ( the heterozygous effect of mutations ) for two diploid
yeast strains differing only in the DNA mismatch - repair deficiency used to elevate the mutation rate in one ( mutator )
strain . -
pubmed
In order to investigate the presence of membrane protein defects we investigated the erythrocyte membrane protein composition and phosphorylation in 22
children with
leukemia at diagnosis and during the remission phase . -
pubmed
Sixteen
children had
acute lymphoblastic leukemia (
ALL ) , three had
chronic myeloid leukemia (
CML ) and three had
acute myeloid leukemia (
AML ) . -
pubmed
The
STI and
HIV epidemics are interdependent . -
pubmed
Similar behaviours , such as frequent unprotected intercourse with different partners , place people at high risk of both
infections , and there is clear evidence that conventional STIs increase the likelihood of
HIV transmission . -
pubmed
Several studies have demonstrated a strong association between both
ulcerative and non - ulcerative STIs , and
HIV infection ( Cameron 1989 , Laga 1993 ) and there is biological evidence that the presence of an
STI increases shedding of
HIV and that
STI treatment reduces
HIV shedding ( Cohen 1997 , Robinson 1997 ) . -
pubmed
Therefore ,
STI control may have the potential to contribute substantially to
HIV prevention . -
pubmed
In Mwanza , the incidence of
HIV infection in the intervention groups ( strengthened syndromic management of
STIs in primary care clinics ) was 1.2 % compared with 1.9 % in the control groups ( OR=0.58 , 95 % CI 0.42 - 0.70 ) , corresponding to a 38 % reduction ( 95%CI 15 % to 55 % ) in
HIV incidence in the intervention group . -
pubmed
REVIEWERS ' CONCLUSIONS : There is limited evidence from randomised controlled trials for
STI control as an effective
HIV prevention strategy . -
pubmed
Improved
STI treatment services have been shown to reduce
HIV incidence in an environment characterised by an emerging HIV epidemic ( low and slowly rising prevalence ) , where
STI treatment services are poor and where
STIs are highly prevalent . -
pubmed
Such trials should aim to measure a range of factors that include health seeking behaviour and quality of treatment as well as
HIV ,
STI and other biological endpoints . -
pubmed
The results show that although FNAC is relatively inexpensive and minimally invasive , it can not be relied upon to provide an accurate tissue diagnosis , may fail to identify
malignancy and does not prevent
patients undergoing surgery for non - neoplastic conditions . -
pubmed
Increased urine
catecholamine levels were observed only in the
patient with
neuroblastoma . -
pubmed
iron infusions represent a practical alternative to oral
iron and can be safely administered to
PD patients in an outpatient setting . -
pubmed
[
Epstein - Barr virus - encoded small RNA and
oncogenesis ] . -
pubmed
Patients with a greater
drop in blood pressure experienced no improvement in exercise - induced
ischemia . -
pubmed
METHODS - From May 1998 to July 2000 , 33
patients with clinical and laboratory diagnosis of
persistent ductus arteriosus underwent attempts at percutaneous implantation of the Amplatzer prosthesis . -
pubmed
All
patients were followed up with periodical clinical and echocardiographic evaluations to assess the presence and degree of residual shunt and possible complications , such as
pseudocoarctation of the aorta and left
pulmonary artery stenosis . -
pubmed
The purpose of the present study was to obtain insight into the natural development of adaptive intimal thickening and
atherosclerosis in the arterial tree of
human species . -
pubmed
Within elderly
humans , features of advanced
atherosclerotic disease , a lipid - rich core and macrophages , can be observed in the intimal layer of artery types that are recognised for their relation with clinical syndroms as well as artery types that remain clinically silent . -
pubmed
Assuming that the mechanisms of action of
apomorphine are similar in
humans and
animal models , its use for the treatment of
erectile dysfunction (
ED ) validates the emerging idea that erectile response could be enhanced by acting directly within the central nervous system ( CNS ) . -
pubmed
Transformed and
tumor - derived
human cells exhibit preferential sensitivity to the
thiol antioxidants ,
N - acetyl cysteine and
penicillamine . -
pubmed
To test whether sensitivity to antioxidants is a general property of immortalized
human cells , including fully transformed cells , 12
tumor - derived cell lines were treated with
PEN , the more potent of the two antioxidants . -
pubmed
High - dose
samarium-153 ethylene diamine tetramethylene phosphonate : low
toxicity of skeletal irradiation in
patients with
osteosarcoma and
bone metastases . -
pubmed
Theiler ' s virus infection of the central nervous system ( CNS ) induces an immune - mediated
demyelinating disease in susceptible
mouse strains , such as SJL / J , and serves as a relevant infectious model for
human multiple sclerosis . -
pubmed
Therefore , the susceptibility of SJL / J
mice is not due to the lack of an early functional Theiler 's murine
encephalomyelitis virus - specific CTL response . -
pubmed
OBJECTIVE : We sought to determine the results of surgical treatment of
patients with
tetralogy of Fallot and
pulmonary atresia with or without major aortopulmonary collateral arteries , to clarify variables affecting early and late mortality , and to expose late , nonfatal events affecting surgical
patients . -
pubmed
Twenty - two ( 6.6 % )
patients underwent reopening of the
ventricular septal defect for high right ventricular pressure . -
pubmed
CONCLUSIONS : Surgical repair of
patients with simple or complex forms of
tetralogy of Fallot with
pulmonary atresia can be achieved with low early mortality . -
pubmed
There was osteogenic
relapse involving the bone of the orbit , 20 days after macroscopically complete excision of the primary
tumour when the
patient was 12 weeks old . -
pubmed
Ectopic expression of cell cycle markers in models of induced programmed cell
death in
dopamine neurons of the
rat substantia nigra pars compacta . -
pubmed
BACKGROUND :
Cancer gene therapy is now being developing to provide new strategies for the treatment of
human tumors . -
pubmed
Different contribution of apoptosis to the antiproliferative effects of
diosgenin and other
plant steroids ,
hecogenin and
tigogenin , on
human 1547 osteosarcoma cells . -
pubmed
We compared the biological activity of
diosgenin with
hecogenin and
tigogenin ,
plant steroids structurally close to
diosgenin , on proliferation rate , cell cycle distribution and apoptosis in
human 1547 osteosarcoma cells . -
pubmed
To evaluate the vector competence of
Culex tarsalis Coquillett for
West Nile virus (
WN ) , females reared from larvae collected in Huntington Beach , Orange County , CA , were fed on 2 - 3 - day - old
chickens previously inoculated with a New York
strain ( Crow 397 - 99 ) of WN . -
pubmed
Sixty - four
patients with mild to moderate
AD were retrospectively selected by two European centres . -
pubmed
We reviewed autopsy material from
patients who died of diffuse
alveolar damage in the clinical setting of
pulmonary fibrosis , both idiopathic and with background fibrosing
alveolitis with
connective tissue disorders (
FA - CTDs ) , and compared them with cases of acute
interstitial pneumonia . -
pubmed
Capsaicin - induced
hyperalgesia and mu - opioid - induced antihyperalgesia in male and female
Fischer 344 rats . -
pubmed
The influence of sex in determining responses to opioid analgesics has been well established in
rodents and
monkeys in assays of short - lasting , phasic
pain . -
pubmed
The purpose of this investigation was to use a
capsaicin model of
tonic pain to evaluate sex differences in
hyperalgesia and mu - opioid - induced antihyperalgesia in
Fischer 344 ( F344 ) rats . -
pubmed
Capsaicin injected into the tail produced a dose - dependent thermal
hyperalgesia in males and females , with the dose required to produce a comparable level of
hyperalgesia being 3.0 - fold higher in
males than in females . -
pubmed
These data contrast with the finding that mu - opioids are more potent in
male rodents in assays of phasic
pain , thus suggesting that distinct mechanisms underlie male and female sensitivity to opioid antinociception in phasic and tonic
pain models . -
pubmed
These findings emphasize the need to test male and female
rodents in tonic
pain assays that may have greater relevance for
human pain conditions . -
pubmed
Tobacco smoking , motor exhaust fumes , and general air pollution in relation to
lung cancer incidence . -
pubmed
[ On the carcinogenic substances in the external surroundings of
man and the prevention of
cancer ] . -
pubmed
Forty - six
patients with
AD , 7
patients with
FLD and 34 normal controls ( CTR ) were included in the study . -
pubmed
Peripheral blood mononuclear cell ( PBMC )
cytotoxicity against
S. - pubmed
In the present study , we injected
rats with multiple doses of
dimethylnitrosamine for 4 weeks and used
rats with severe
LC to determine whether
colchicine treatment improved liver functions and resolved
cirrhotic nodules . -
pubmed
Haemangiopericytoma (
HPT ) is a rare
neoplasm that can occur in any part of the
human body . -
pubmed
In this report , we describe the case of a
patient with sudden severe upper
abdominal pain caused by primary
HPT in the greater omentum . -
pubmed
, is one of the most important
fungal diseases that has been shown to cause significant yield losses on
chickpeas in Kermanshah province , Iran . -
pubmed
Disease resistance of four
chickpea cultivars , Hashem , Jam , ILC-482 and Bivanij , were evaluated against isolates from each of three groups separately and in combination in the greenhouse and field conditions ( with 4 replications ) . -
pubmed
BACKGROUND : Mesorectal margin
tumour involvement is a predictor of local
recurrence in rectal
carcinoma and an indication for postoperative radiotherapy in suitable
patients . -
pubmed
Despite advances in coronary angioplasty for
acute myocardial infarction (
MI ) , the mortality rate for
patients presenting with
cardiogenic shock remains high . -
pubmed
This case review describes the management of a
patient with a non - ST segment elevation
MI complicated by
cardiogenic shock . -
pubmed
We examined the relationship between left atrial volumetric remodeling and objective measures of exercise capacity in
patients with nonobstructive
hypertrophic cardiomyopathy (
HCM ) . -
pubmed
This simple noninvasive measure of LA size may provide a long - term indication of the effects of chronically elevated filling pressures in
patients with
HCM and further studies testing its prognostic value are necessary . -
pubmed
The aim of the present study was to determine the mechanism of
angiotensin - converting enzyme inhibitor ( ACEI ) on the progression of
rat hepatic fibrosis . -
pubmed
Previously , we generated
mice carrying the R192Q mutation , associated with
human familial hemiplegic migraine type-1 , and showed first evidence of enhanced presynaptic
Ca ( 2 + ) influx [ Neuron 41 ( 2004 ) 701 ] . -
pubmed
Here , we characterize transmitter release in detail at
mouse R192Q NMJs , including possible gene - dosage dependency , progression of changes with age , and associated morphological damage and
muscle weakness . -
pubmed
Spinal endoscopy has been widely used to treat
patients with
cervical , thoracic , and lumbosacral disorders safely and effectively . -
pubmed
In order to obtain a comprehensive picture of the molecular events regulating cutaneous photodamage of intact
human epidermis , suction
blister roofs obtained after a single dose of in vivo ultraviolet ( UV)B exposure were used for microarray profiling . -
pubmed
OBJECTIVE : To evaluate the clinicopathologic features and prognosis of
patients with
orbital lymphomas . -
pubmed
METHODS : Clinical and pathologic data of 35
patients with biopsy - proven
orbital lymphoma diagnosed at a tertiary care hospital from 1992 to 2001 were reviewed . -
pubmed
Survival of
patients was compared according to age , gender ,
disease site , extent of disease ,
tumor grade , and treatment modality by using log rank test . -
pubmed
Twenty - three
patients ( 66 % ) were diagnosed with
low - grade lymphoma , and 12
patients ( 34 % ) were found to have
high - grade lymphoma . -
pubmed
Among low - grade
lymphomas , marginal zone
lymphoma ( n=6 ) ,
follicle center cell lymphoma ( n= 6 ) , and
small lymphocytic lymphoma ( n=5 ) were common entities , whereas
diffuse large cell B - cell lymphoma ( n=5 ) was the most common entity in
patients with
high - grade lymphoma . -
pubmed
Overall , 13 ( 37 % )
patients died , 6 with high - grade and 7 with
low - grade lymphoma . -
pubmed
The seasonality of
sarcoidosis in symptomatic , recently diagnosed
patients with
Lofgren ' s syndrome was evaluated to help better understand the possible causative factor(s ) in the pathogenesis of
sarcoidosis . -
pubmed
METHODS : Four hundred and ninety - two consecutive
patients with
sarcoidosis were investigated . -
pubmed
PURPOSE : Immediate spica cast application is the standard of care for young
children with isolated
femur fractures . -
pubmed
CONCLUSIONS : The single - leg spica can safely , effectively manage low - energy
femur fractures in young
children . -
pubmed
A
seizure -
paralysis repertoire characteristic of
Drosophila " bang - sensitive " mutants can be evoked electroconvulsively in tethered
flies , in which behavioral episodes are associated with synchronized spike discharges in different body parts . -
pubmed
BACKGROUND : Data on the subtypes of
HIV in a population help in predicting the potential foci of epidemic , tracking the routes of
infection and following the patterns of the virus ' genetic divergence . -
pubmed
Globally , the most prevalent
HIV infection is the
HIV-1 subtype C. In Asia , predominant subtypes of
HIV-1 are B , C , and CRF-01AE . -
pubmed
As the prevalence of
HIV in Pakistan continues to rise , more work needs to be done to track the
infection , and to analyze the
strains of
HIV spreading through the country . -
pubmed
Correlation between the appearance of neuropeptides in the
rat trigeminal
ganglion and reinnervation of the healing root socket after tooth extraction . -
pubmed
Most
human infections with the protozoan parasite
Toxoplasma gondii are asymptomatic , but severe symptoms can occur in immunocompromised patients , in developing foetuses , and in
ocular infections in immunocompetent individuals . -
pubmed
Such a scenario can be found following
infection of adult
mice with an immunosuppressive variant of
lymphocytic choriomeningitis virus (
LCMV ) referred to as
clone 13 . -
pubmed
Interestingly , the combination of
ZD4054 and
paclitaxel produced additive antitumor effects , with 40 % of
mice remaining
tumor - free , supporting a rationale for the clinical use of
ZD4054 as monotherapy or in combination with cytotoxic drugs . -
pubmed
Peritoneal samples from the omentum of adult
sheep were isolated immediately after the
deaths of the
animals and were transferred to the laboratory in cooled Krebs - Ringer
bicarbonate solution ( 4 degrees C , pH 7.5 ) bubbled with 95 %
O2/5 %
CO2 . -
pubmed
Those findings , combined with the results of the present study , clearly indicate that intraperitoneal administration of
digitalis glycosides may have some beneficial effect in
PD patients ; however the specific clinical implications need further investigation . -
pubmed
Objectives To establish the lifetime prevalence of clinically manifest
orofacial herpes and its relationship with herpes simplex virus (
HSV ) serotype in the French general population . -
pubmed
PATIENTS / METHODS : Subjects ( N = 2796 ) were serotyped for
HSV1 and
HSV2 and provided data on
herpetic symptoms by questionnaire . -
pubmed
Retinoic acid downregulates microRNAs to induce abnormal development of spinal cord in
spina bifida rat model . -
pubmed
To this end , we have studied the mechanism of microRNAs involved in the morphogenesis of the spinal cord in
all - trans - retinoic acid (
RA)-treated
spina bifida rat fetus . -
pubmed
A 68 - year - old
man had
malaise ,
weight loss , and enlarged right cervical lymph nodes . -
pubmed
Because of their effects on
sodium ,
vasopressin antagonists need to be carefully monitored to ensure that serum
sodium levels do not increase too quickly and put the
patient at risk for overcorrection or
osmotic demyelination syndrome . -
pubmed
In addition ,
patients need to be monitored for signs of
dehydration secondary to increased urine excretion . -
pubmed
To date , studies have not consistently shown improvements in
patient symptoms or
weight reduction . -
pubmed
CONCLUSION : Based on data from available clinical trials ,
vasopressin antagonists may offer a new treatment option for
patients with
congestive heart failure . -
pubmed
Azacitidine has been shown to have survival benefits in
patients with high - risk
myelodysplastic syndrome (
MDS ) , and has activity in the treatment of
acute myelogenous leukemia (
AML ) . -
pubmed
In a formulation feasibility pilot study , four
subjects with solid
malignant tumors ,
AML or
MDS received single oral doses of 60 or 80 mg
azacitidine . -
pubmed
Effects of
glycine on motor performance in
rats after
traumatic spinal cord injury . -
pubmed
In order to assess the effects of
glycine administration on motor performance after
SCI , we used fifteen male
Wistar rats distributed into three groups : sham ( n = 3 ) ,
spinal - cord injury ( n = 6 , ) and
spinal cord injury +
glycine ( n = 6 ) . -
pubmed
Results showed that for all
animals with
spinal - cord injury , scores in the beam - walking increased , which is an indication of increased motor deficit . -
pubmed
The aim of the study was to examine the association between estimated
glomerular filtration rate ( GFR ) , presence of
CAD , and prognosis in
patients with reversible perfusion defects at gated single - photon emission computed tomography ( g - SPECT ) . -
pubmed
RESULTS :
GFR was lower in
patients with
CAD and after adjusting for several clinical characteristics through multivariate logistic regression analysis , reduced ( & lt;60 mL / min/1.73 m(2 ) ) GFR remained a significant predictor of
CAD ( HR 1.80 , 95 % CI 1.04 to 3.12 , P = .036 ) . -
pubmed
CONCLUSIONS : In
patients with a positive g - SPECT scan ,
GFR is an accurate marker of
CAD and is directly correlated to the extent of
myocardial ischemia . -
pubmed
Drug addiction is a common
brain disorder that is extremely costly to the
individual and to society . -
pubmed
BACKGROUND : Recent studies have indicated that many
children with
autism spectrum disorders present with language difficulties that are similar to those of
children with specific
language impairments , leading some to argue for similar structural deficits in these two disorders . -
pubmed
METHODS & amp ; PROCEDURES :
Adolescents with specific
language impairments ( mean age = 15;3 , n = 14 ) and
autism spectrum disorders plus
language impairment (
autism plus
language impairment ; mean age = 14;8 , n = 16 ) were recruited alongside typically developing adolescents ( mean age = 14;4 , n = 17 ) . -
pubmed
administration of
capsaicin induced dose - dependent mechanical
allodynia in wild - type
mice ( markedly reducing both the threshold force necessary to induce paw withdrawal and the latency to paw withdrawal induced by a given force ) . -
pubmed
Patients with partial response and those with stable disease whose
tumor markers decreased by 50 % or more were classified as the effective group . -
pubmed
The genomic DNA G+C content of
strain NHBX5(T ) was 44.9 mol% . -
pubmed
The level of DNA - DNA relatedness between
strain NHBX5(T ) and
S. - pubmed
Coinfection with
Coxiella burnetii in
infectious endocarditis . -
pubmed
Agrobacterium radiobacter bacteremia in a child with
acute lymphoblastic leukemia . -
pubmed
BACKGROUND : Agrobacteria are Gram - negative tumorigenic plant pathogens that rarely cause
infections in
humans . -
pubmed
METHODS : The authors describe a 7 - year - old
boy with
acute lymphoblastic leukemia who carried a central venous catheter and developed
bacteremia due to
Agrobacterium radiobacter (
A. - pubmed
Catheter removal for the clearance of
bloodstream infections due to
A. - pubmed
AIMS : Cardiac resynchronization therapy is currently used in selected
patients with end - stage
heart failure . -
pubmed
We report an unusual
death of a seemingly healthy 26 - year - old
man due to diffuse metastasization of
adrenal paraganglioma caused by
rupture of the primitive tumour with subsequent massive
haemorrhage after a relatively minor
trauma . -
pubmed
Pulmonary vein isolation alone in
patients with persistent
atrial fibrillation : an ablation strategy facilitated by antiarrhythmic drug induced reverse remodeling . -
pubmed
INTRODUCTION : Pulmonary vein isolation ( PVI ) alone has been thought to be insufficient in
patients with persistent
atrial fibrillation (
PersAF ) . -
pubmed
METHODS AND RESULTS : Seventy - one consecutive
patients ( 59.4 + - 9.8 years ) with
PersAF and prior
AAD failure were treated with oral
dofetilide ( 768 + - 291 mcg / day ) for a median of 85 days pre - PVI . -
pubmed
Thirty - five
patients with paroxysmal ( P )
AF not treated with an AAD served as controls . -
pubmed
The 6 and 12 mos AAD - free response to ablation was 76 % and 70 % , respectively , in
PersAF patients , similar to the 80 % and 75 % , response in
PAF patients ( P = NS ) . -
pubmed
A decline in Pdur in response to
dofetilide was the only predictor of long - term clinical response to PVI in
patients with
PersAF . -
pubmed
CONCLUSIONS : Pre - treatment with
AAD resulted in a decrease in Pdur suggesting reverse atrial
electrical remodeling in
PersAF patients . -
pubmed
Effect of topical glucocorticoid treatment in
chinchilla model of lipopolysaccharide induced
otitis media with
effusion . -
pubmed
LPS ( 300 mug ) was injected into the superior
bullae of
chinchillas to induce
OME . -
pubmed
After 96 h ,
chinchillas were euthanized , samples of
middle ear effusion ( MEE ) were collected , and temporal bones were removed for histopathological examination . -
pubmed
The frequency of
patients with
hypertension and
hyperlipidemia was recorded at 1 year . -
pubmed
Oxidative stress and
cytotoxicity generated by dental composites in
human pulp cells . -
pubmed
Pseudomonas aeruginosa is a primary cause of
opportunistic infections . -
pubmed
Our aim was to study the influence of these polymorphism in study groups with
HIV - tuberculosis (
TB ) ( n = 110 ) ,
TB ( n = 105 ) , and
HIV ( n = 130 ) compared with healthy controls ( n = 183 ) , using the tetraprimer amplification refractory mutation system ( ARMS)-polymerase chain reaction method . -
pubmed
Chronic gastritis was confirmed in 53.5 % of the
patients and 46.5 % had received protom pump inhibitors ( PPIs ) . -
pubmed
OBJECTIVE : To compare the prevalence of
metabolic syndrome (
MetS ) and its components in second - generation antipsychotic ( SGA)-treated and SGA - naive
children ; and to explore the utility of clinical markers , such as waist circumference ( WC ) and
body mass index ( BMI ) , as screening tools for
MetS. -
pubmed
WC measurement is a simple and sensitive screening tool for determining
MetS risk in SGA - treated
children . -
pubmed
Exercise capacity in
children with isolated congenital complete
atrioventricular block : does pacing make a difference ? -
pubmed
Therefore , we have investigated the exercise capacity of a group of contemporary
children with
CCAVB . -
pubmed
Sixteen
children ( mean age 11.5 + - 4 ; seven
boys , nine
girls ) with
CCAVB were tested . -
pubmed
Hemimaxillectomy
patients present with abrupt alterations in the physiologic processes of the maxillae , along with increased
anxiety levels due to sudden impairment in esthetics , mastication , speech , deglutition and
hypernasal speech . -
pubmed
This case report illustrates the multidisciplinary approach to rehabilitate a
patient , who had undergone maxillectomy on the right side , due to
carcinoma alveolus . -
pubmed
Effect of immunotherapy with bapineuzumab on cerebrospinal fluid biomarker levels in
patients with mild to moderate
Alzheimer disease . -
pubmed
PATIENTS : Forty - six
patients with mild to moderate
Alzheimer disease . -
pubmed
Our results show that pretreating
rat neonatal cardiomyocytes with
NaHS , a
H ( 2 ) S donor , reduced the levels of ROS during the
hypoxia / reoxygenation ( H / R ) condition . -
pubmed
[ Comparative study on
tumor cell apoptosis in vitro induced by extracts of
Stellera chamaejasme ] . -
pubmed
SUMMARY : Advanced diagnostic and therapeutic endoscopic techniques are changing the paradigm of care in
patients with early
gastric cancers . -
pubmed
The
haloperidol - induced
catalepsy , milk - induced
leukocytosis , and nasal provocation in vivo studies in
rats proved that the fast - dissolving films of
levocetirizine dihydrochloride produced a faster onset of action compared to the conventional tablets . -
pubmed
The three
H5N2 isolates genetically characterized as low pathogenic AIV were closely related to the
strains previously isolated from aquatic wild birds in Japan and also to the Korean strains isolated from aquatic birds in recent years . -
pubmed
Rapid eye movement sleep behavior disorder in
adults younger than 50 years of age . -
pubmed
A
rabbit iliac artery injury model was constructed . -
pubmed
OBJECTIVE : To investigate factors determining pulmonary vein reconnection in
patients undergoing repeat catheter ablation for recurrent
atrial fibrillation following cryoballoon ablation . -
pubmed
METHODS : Fifty - one consecutive
patients undergoing repeat catheter ablation for recurrent
atrial fibrillation following initial cryoballoon ablation underwent retrospective assessment of initial cryoablation characteristics , including balloon and vein sizes , venogram occlusion score , balloon freezing time from 0 to -30 C , nadir temperature , and balloon warming time from -30 to +15 C , recorded during the initial cryoballoon procedure . -
pubmed
In affected
men ,
LUTS /
BPH is believed to result from benign proliferation of the prostate resulting in
bladder outlet obstruction . -
pubmed
We describe a
patient with spontaneous resolution of
SFD in DSM documented by serial spectral domain optical coherence tomography ( SD - OCT ) . -
pubmed
A 28 - year - old female Japanese
patient presented with
blurred vision in both eyes . -
pubmed
Three months later , the
patient achieved spontaneous resolution of
SFD without treatment . -
pubmed
We report the perioperative course of a
patient with long standing
ankylosing spondylitis with severe
dysphagia due to large
anterior cervical syndesmophytes at the level of the epiglottis . -
pubmed
Spinal cord injury and contractile properties of the
human tibialis anterior . -
pubmed
The contractile properties and the fatigability of the tibialis anterior muscle ( TA ) were tested in 8
spinal cord injured (
SCI ) and 8 control
individuals . -
pubmed
All indices of contractile speed were slower in the
spinal cord injured subjects than in the controls . -
pubmed
METHODS : A total of 120
UC patients and 125 age and sex matched controls with no
GI symptoms were enrolled . -
pubmed
RESULTS : Out of the 120
UC patients , 74 were male with mean+-SD age of 45.6 + -17.5years . -
pubmed
LPO in
UC patients was significantly increased ( p<0.01 ) while
GSH was significantly decreased ( p<0.01 ) as compared to controls . -
pubmed
OCTT and SIBO were significantly higher in
UC patients as compared to controls . -
pubmed
Minocycline , a microglial inhibitor , diminishes terminal
patients '
delirium ? -
pubmed
OBJECTIVES : The aim of this study was to investigate specific fears related to
hypoglycemia in
adults with
type 1 diabetes and to investigate how aspects of fear of
hypoglycemia may differ between genders . -
pubmed
METHODS : A cross - sectional study with questionnaires sent to 636
patients with
type 1 diabetes , aged 18 - 75 years , who attended the outpatient clinic at St. Olavs Hospital , Trondheim , Norway . -
pubmed
Rodent models of juvenile stress appear to support this hypothesis because juvenile stress can result in reduced activity / exploration and enhanced
anxiety , although results are not always consistent . -
pubmed
RESULTS : Nine
colistin - resistant
strains were detected in a collection of 739 enterobacteria (
S. - pubmed
METHODS : This randomized clinical trial was conducted on 90
asthmatic patients who were randomly divided into inhalation technique group with spacer , inhalation technique group without spacer , and a control group . -
pubmed
Differential prognostic impact of resting heart rate in older compared with younger
patients with chronic
heart failure -- insights from TIME -
CHF . -
pubmed
BACKGROUND : There is little information regarding the prognostic role of resting heart rate ( HR ) in older compared with younger
patients with chronic
heart failure (
HF ) . -
pubmed
METHODS AND RESULTS : In
patients enrolled in the Trial of Intensified Medical Therapy in Elderly
Patients With
Congestive Heart Failure ( TIME -
CHF ) with
sinus rhythm , effects of baseline HR ( & gt;=70 vs & lt;70 beats / min [ bpm ] ) on 18 - month outcomes were compared between older ( & gt;=75 years ; n = 186 ) and younger ( & lt;75 years ; n = 141 )
patients . -
pubmed
CONCLUSIONS : In contrast to
HF patients aged & lt;75 years , we found no association between HR and worse outcomes in
HF patients aged & gt;=75 years . -
pubmed
OBJECTIVES : To compare the treatment efficacy of intravitreal
bevacizumab ( IVB ) and the combination of IVB and intravitreal
triamcinolone (
IVT ) for
DME patients . -
pubmed
BACKGROUND :
Radial artery ( RA ) occlusion (
RAO ) is not rare in
patients undergoing coronary intervention by transradial approach ( TRCI ) . -
pubmed
METHODS : Between June 2006 and March 2010 , all
patients who underwent TRCI were classified according to the
weakness of RAP after removing compression bandage with confirmation by Doppler ultrasound for the first 30 consecutive
patients . -
pubmed
There were two
patients experienced persistent
RAO with a success rate of 98.9 % and RAO in 0.075 % of
patients after ulnar artery compression was applied . -
pubmed
The group of Negative - Stranded RNA Viruses ( NSVs ) includes many
human pathogens , like the
influenza ,
measles ,
mumps , respiratory syncytial or
Ebola viruses , which produce frequent epidemics of disease and occasional , high mortality outbreaks by transmission from animal reservoirs . -
pubmed
We assessed role of
MBL deficiency in
HIV-1 and
schistosoma infections in Zimbabwean adults enrolled in the Mupfure Schistosomiasis and
HIV Cohort ( MUSH Cohort ) . -
pubmed
Further ,
EIAV infection can cause lesions on the spleen and lymph nodes , similar to those frequently observed in
horses , the natural hosts . -
pubmed
Protection of testis through antioxidant action of
Mallotus roxburghianus in
alloxan - induced
diabetic rat model . -
pubmed
About 90 % of
diabetic patients have been associated with
reproductive impairments . -
pubmed
roxburghianus was given to male albino
Wistar rats by oral gavage to study the
acute toxicity . -
pubmed
CONCLUSION : MRME treatment to
diabetic rats improves
diabetes induced oxidative damage in testis as well as provides protection to testis . -
pubmed
Gait variability in
multiple sclerosis : a better falls predictor than EDSS in
patients with low disability . -
pubmed
This longitudinal study aims to compare the role of stride time variability ( STV ) and EDSS for predicting falls in 50
patients with
multiple sclerosis with
low disability . -
pubmed
To show the potential of the plugin we have applied it in a study of two miRNAs that are particularly relevant in
human melanoma progression , miR-146a and miR-214 . -
pubmed
Hypoglycemia is a very common in
type 1 diabetic persons and can occur at any age . -
pubmed
It is always threatening to the well - being of
patients with
Type 1 diabetes mellitus (
T1DM ) since
hypoglycemia leads to
seizures or
loss of consciousness and the possible development of permanent
brain dysfunction under certain circumstances . -
pubmed
Because of that , an accurate continuing
hypoglycemia monitoring system is a very important medical device for
diabetic patients . -
pubmed
A clinical study of 16
children with
T1DM is given to illustrate the good performance of ELM . -
pubmed
Newborn
human infants display robust
pain behaviour and specific cortical activity following noxious skin stimulation , but it is not known whether brain processing of nociceptive information differs in infants and adults . -
pubmed
These data support our hypothesis and indicate important postnatal changes in the encoding of mechanical
pain in the
human brain . -
pubmed
Efficacy of a single dose of
trazodone hydrochloride given to
cats prior to veterinary visits to reduce signs of transport- and examination - related
anxiety . -
pubmed
OBJECTIVE To evaluate the efficacy of a single dose of
trazodone for reducing
anxiety in
cats during transport to a veterinary hospital and facilitating handling during veterinary examination . -
pubmed
ANIMALS 10 healthy client - owned
cats ( 2 to 12 years of age ) with a history of
anxiety during transport or veterinary examination . -
pubmed
Owners scored their
cat 's signs of
anxiety before , during , and after transport and examination . -
pubmed
RESULTS Compared with placebo ,
trazodone resulted in a significant improvement in the
cats ' signs of
anxiety during transport . -
pubmed
CONCLUSIONS AND CLINICAL RELEVANCE Oral administration of a single dose of
trazodone to
cats prior to a veterinary visit resulted in fewer signs of transport- and examination - related
anxiety than did a placebo and was generally well tolerated by most
cats . -
pubmed
METHODS :
Scar fibroblasts were isolated from deprecated
human hypertrophic scar tissue and then sub - cultured . -
pubmed
Then
human hypertrophic scar tissue was embedded into the incision . -
pubmed
Tobacco smoking has been linked as a risk factor for
TB . -
pubmed
MATERIALS AND METHODS :
Pulmonary TB patients aged between 18 and 65 years were enrolled and followed - up until treatment completion . -
pubmed
Cardio - Thoracic Ratio Is Stable , Reproducible and Has Potential as a Screening Tool for
HIV-1 Related
Cardiac Disorders in Resource Poor Settings . -
pubmed
OBJECTIVES : The preferred countermeasure to avoid exercise - related
hypoglycemia was investigated in a group of
patients with
type 1 diabetes participating in a stressful event , a 24x1 - hour relay marathon . -
pubmed
Glycemia fell by the end of the races ( p=0.006 ; median -1.8 mmol L-1 ; interquartile range -0.4 mmol L-1 to -5.3 mmol L-1 ) , despite 9
patients being
hyperglycemic at the start . -
pubmed
Of the
patients , 14 concluded the race with glycemia on target , and 4
patients were
hyperglycemic . -
pubmed
However , the snail
Eobania vermiculata possesses a
diverticulum that is three times longer than the spermatophore it receives . -
pubmed
Here , we report that the love - dart mucus of this species contains a contraction - inducing substance that shortens the
diverticulum , an effect that is only properly revealed when the mucus is applied to another helicid species ,
Cornu aspersum This finding suggests that
E. - pubmed
Effect of various
selenium doses on
chromium ( IV )-induced
nephrotoxicity in a male
chicken model . -
pubmed
This study demonstrated that
Cr ( VI ) can result in
kidney oxidative damage in male
chickens , and
Se of certain dose has the protective effects against
Cr ( VI )-induced
nephrptoxicity . -
pubmed
OBJECTIVE :
Alchornea floribunda leaves are widely used in ethnomedicine for the management of
immuno - inflammatory disorders . -
pubmed
17beta - Estradiol prevents
mesenteric injury induced by occlusion of the proximal descending aorta in male
rats . -
pubmed
Therefore , this study investigated the role of
17beta - estradiol on
visceral ischemia - reperfusion ( I / R )
injury after descending
aorta occlusion in male
rats . -
pubmed
METHODS : Mesenteric
ischemia was induced in male
Wistar rats by placing a 2F Fogarty arterial embolectomy catheter ( Edwards Lifesciences , Irvine , Calif ) in the descending aorta , which remained occluded for 15 minutes , followed by reperfusion for up to 2 hours . -
pubmed
Rats were divided into four groups : ( 1 )
rats that underwent surgical manipulation only ( sham , n = 22 ) ; ( 2 )
rats that underwent I / R
injury ( n = 22 ) ; ( 3 )
rats treated with intravenous
17beta - estradiol ( 280 mug / kg ) 30 minutes before I / R ( n = 22 ) ; ( 4 ) or at the beginning of reperfusion ( n = 22 ) . -
pubmed
However , the depletion of intragraft B cells during acute rejection did not affect
steroid resistance ,
proteinuria , graft function at 2 years follow - up , or
patient and graft survival at a median follow - up of 4.1 years ( range , 2.0 - 6.2 years ) . -
pubmed
CASE DESCRIPTION : A 16 year - old
female who presented with initial ear , nose and throat manifestations who later progressed to severe
renal disease , requiring hemodialysis after 11 months of unique laryngeal involvement . -
pubmed
Adult
patients with irretrievable
CBDS who had plastic stent insertions throughout the follow - up period were included . -
pubmed
In the ESE group , 4/28
patients had duct clearance in subsequent ERCPs , 1/28 patient presented with a blocked stent , and no biliary - related
deaths were observed . -
pubmed
Postoperative disseminated intravascular coagulation in a pregnant
patient with Blue Rubber
Bleb Nevus Syndrome presenting with
acute intestinal obstruction : Case report and literature review . -
pubmed
This is the first report of a life - threatening
postoperative disseminated intravascular coagulation in such
patients . -
pubmed
CASE PRESENTATION : Twenty - five year - old female pregnant
patient presents to the emergency department with colicky
pain and
oligohydramnios . -
pubmed
CONCLUSION : This rare presentation of acute
intestinal intussusception in a
patient with Blue Rubber Bleb
Nevus Syndrome was further complicated with
postoperative coagulation disorder . -
pubmed
Thirty - two
patients with
ankylosing spondylitis were recruited in the experimental group and 36 normal
individuals were recruited to the control group . -
pubmed
BACKGROUND : To prevent
hypocalcemia , this study examined the efficiency of a
calcium supplement formula guided by predicted
calcium requirement in
patients with
renal failure after parathyroidectomy with autotransplantation . -
pubmed
treatment of the triple
transgenic ( APPsw / PS1M146V / TauP301L ) mice with
M344 , at doses as low as 3 mg / kg , significantly prevented
cognitive decline evaluated by Y - maze spontaneous alternation , novel object recognition , and Barnes maze spatial memory tests . -
pubmed
A case of
human ocular dirofilariasis in a patient with
multiple endocrine neoplasia in Northwest Spain . -
pubmed
Effect of
intramural fibroid on uterine and endometrial vascularity in infertile
women scheduled for in - vitro fertilization . -
pubmed
METHODS : 3D power Doppler was used to measure the endometrial volume and blood flow indices in 182
women with
intramural fibroids not affecting the uterine cavity and compared them to a matched control group without
fibroids . -
pubmed
Women with
fibroids & gt ; 4 cm had a significantly higher Endometrial FI ( p = 0.037 ) , and VFI ( p = 0.02 ) . -
pubmed
21 - gene
recurrence assay in
patients receiving intraoperative radiotherapy : are " favorable " characteristics a surrogate for low
recurrence ? -
pubmed
Conclusions : Most
patients selected for IORT based on clinical features were indeed low risk based on
RS . -
pubmed
All three
dogs incurred rectal wall compromise during surgical excision of
anal sac tumours . -
pubmed
The model suggests that the best way to treat
AD is to prevent synaptic separation by identifying
individuals experiencing unusually high rates of ventricle growth and reducing this to more normal levels by shunting or some other technique . -
pubmed
Cutaneous non - epitheliotropic T - cell lymphoma associated with a
fracture site in a
cat . -
pubmed
Case summary : A 7 - year - old male neutered domestic shorthair
cat presented for investigation of a
swelling over the right forelimb . -
pubmed
A 70 's
man underwent subtotal stomach preserving pancreatoduodenectomy(SSPPD)for
pancreatic head cancer . -
pubmed
Cross - sectional studies show that exercise advantage is lost in oligo - amenorrheic
athletes (
OA ) . -
pubmed
Longitudinal studies examining the opposing effects of exercise and
hypogonadism on bone are lacking in
adolescents / young
adults . -
pubmed
Wheat Intolerance and
Chronic Gastrointestinal Symptoms in an Australian Population - based Study : Association Between Wheat Sensitivity ,
Celiac Disease and
Functional Gastrointestinal Disorders . -
pubmed
The aims of this study were to determine the prevalence of self - reported
wheat or gluten sensitivity and doctor diagnosed
CD in an Australian population , define the associated gastrointestinal ( GI ) symptoms and
FGIDs , and determine the relationship between self - reported wheat sensitivity , demographic and medical factors . -
pubmed
We defined self - reported
wheat sensitivity as people who reported gastrointestinal symptoms on ingestion of
wheat based foods , but did not suffer from
celiac disease ,
inflammatory bowel disease or
colorectal cancer . -
pubmed
Infliximab for pediatric
patients with
Crohn ' s disease : A Phase 3 , open - label , uncontrolled , multicenter trial in Japan . -
pubmed
This study aimed to investigate the efficacy , safety , and pharmacokinetic profile of
infliximab ( IFX ) in pediatric
patients with moderate - to - severe
CD and inadequate response to existing treatment . -
pubmed
Pediatric
patients ( aged 6 - 17 years ) with moderate - to - severe
CD were treated with
IFX 5 mg / kg at Weeks 0 , 2 , and 6 , and at 8 - week intervals thereafter until Week 46 , with final evaluation at Week 54 . -
pubmed
CONCLUSIONS : These findings support the effective use of IFX in the treatment of pediatric
patients with
CD where other treatments have proven ineffective . -
pubmed
Investigating the Molecular Mechanism of Aqueous Extract of
Cyclocarya paliurus on Ameliorating
Diabetes by Transcriptome Profiling . -
pubmed
The aqueous extract of
Cyclocarya paliurus leaves ( CPAE ) was reported to be anti -
diabetic . -
pubmed
To elucidate the anti - diabetic effects of CPAE and the underlying potential mechanisms , we performed transcriptome profiling ( RNA - Seq and miRNA - Seq ) on the pancreas and liver from non - diabetic ,
diabetic and
diabetic - CPAE
rats . -
pubmed
Sasa veitchii extract protects against
carbon tetrachloride - induced
hepatic fibrosis in
mice . -
pubmed
Complete improvement after medical treatment was only described in
patients with
DBH and minimal SHR ( p = 0.001 ) . -
pubmed
Treatment success was defined as simultaneous fulfillment of 3 criteria : improvement in
pain , expectations for surgery met , and
patient satisfied with surgery . -
pubmed
Most
patients showed improvement in
pain ( & gt;=88 % ) and high satisfaction ( & gt;=93 % ) and expectation fulfillment ( & gt;=80 % ) postoperatively . -
pubmed
The complex of its antiviral properties and the results of its exhaustive preclinica study , as well as the results of studying its safety and tolerability in adult
HIV - infected patients , including important first data of its use as a specific therapeutic antiHIV /
AIDS drug , certainly indicate on its prospects and its usefulness in clinical use in
patients with
HIV infection , including as part of combination antiretroviral therapy . -
pubmed
RESULTS : 265
patients were enrolled and 82 ( 30.9 % ) developed severe
AKI - defined according to KDIGO stage 2/3 . -
pubmed
Integrated
HIV DNA decline after immunotherapy was also associated with gene expression patterns indicative of cell - mediated activation and NK
cytotoxicity . -
pubmed
METHODS : Twenty - five symptomatic
adolescents aged between 12 and 19 years with a recent ( within 10 days )
SRC and 22 healthy controls aged 13 to 20 years were assessed using the vHIT , Balance Error Scoring System ( BESS ) , and Vestibular Ocular Motor Screening ( VOMS ) tools . -
pubmed
RESULTS : VOR gain in all
adolescents with
SRC was greater than 0.8 , which is considered within normal limits . -
pubmed
CLINICAL RELEVANCE : We do not recommend the assessment of head impulse function in
adolescents with
SRC unless more definitive signs of
peripheral vestibular injury are present . -
pubmed
We recommend using the VOMS to assess symptoms of suspected
SRC injury in
adolescents . -
pubmed
in vitro
cytotoxicity assays showed selective activity of HA - spacer - oliHA conjugates against
cancer cell lines in comparison with standard
human fibroblasts . -
pubmed
The overall rate of biliary
stricture resolution was 44.8 % ( 43 of 96
patients ) with a median follow - up duration of 90.9 months ( interquartile range , 30.9 - 122.3 months ) . -
pubmed
After successful endoscopic treatment ,
biliary strictures recurred in 22
patients ( 57.9 % ) after BD , and in one patient ( 4 % ) after PS treatment . -
pubmed
CONCLUSIONS : Despite a high technical success rate , endoscopic treatment only provided a low rate of resolution of anastomotic
biliary strictures among LDLT
patients and required prolonged treatment duration . -
pubmed
Participants were 188 ( 97 in intervention group and 91 in control group ) people with
HIV and mild to moderate
depressive symptoms recruited in
HIV treatment centers in the Netherlands . -
pubmed
In addition , no significant change was observed in
body weights , yolk sac weight and relative weight organs except the liver and kidney were significantly increased with groups treated with
glyphosate and
Roundup compared to the control group . -
pubmed
BACKGROUND / AIMS : To assess risk factors for
serous retinal detachment (
SRD ) in the fellow eye of
patients with
central serous chorioretinopathy (
CSC ) based on clinical data and multimodal imaging findings , including baseline late - phase
indocyanine green angiography ( ICGA ) . -
pubmed
METHODS : Consecutive
patients with unilateral
CSC were retrospectively assessed . -
pubmed
RESULTS : Sixty - eight
patients with unilateral
CSC were included . -
pubmed
CONCLUSION : These results suggest that the fellow eyes with specific findings on multimodal imaging in
patients with unilateral
CSC should be carefully followed up for possible incidence of
CSC . -
pubmed
Fluorescence In Situ Hybridization ( FISH ) Detection of Viral Nucleic Acids in Oncolytic H-1 Parvovirus - Treated
Human Brain Tumors . -
pubmed
The primary purpose of the trial was to evaluate the safety of an oncolytic parvovirus , H-1PV ( ParvOryx ) , in recurrent
glioblastoma patients . -
pubmed
The FISH method allowed the detection - for the first time in
humans - of H-1PV replication markers in
brain tumors of parvovirus - treated
patients . -
pubmed
Associations between model - predicted
rivaroxaban exposure and
patient characteristics and efficacy and safety outcomes in the treatment of
venous thromboembolism . -
pubmed
The first outbreak of
ZIKV was reported in 2007 in the Pacific area followed by another severe outbreak , which occurred in 2013/2014 and subsequently ,
ZIKV spread to all other Pacific islands . -
pubmed
A broad spectrum of
ZIKV associated
neurological malformations in neonates and adults have driven this deadly virus into the limelight . -
pubmed
Though tremendous efforts have been focused on understanding the molecular basis of
ZIKV , the viral proteins of
ZIKV have still not been studied , extensively . -
pubmed
Hepatic involvement in
COVID-19 patients : Pathology , pathogenesis , and clinical implications . -
pubmed
We develop a mathematical model for fitness landscapes generated by such tradeoffs , based on experiments that determine the antibiotic dose - response curves of
Escherichia coli strains , and previous observations on antibiotic resistance mutations . -
pubmed
RESULTS : In the HTK group , 52
patients ( 40 % ) exhibited either
PGD or
PGNF , compared to 20
patients ( 31 % ) in the
IGL-1 group ( P = .208 ) . -
pubmed
Patients from the HTK group had higher mean values for cryoprecipitate transfusion ( P = .0064 ) , first day serum
lactate ( P = .0099 ) , higher incidence of
vascular complications ( 11 % vs 2 % in the
IGL-1 group ; P = .0226 ) , but a lower incidence of
infection ( 7 % vs 28 % in the
IGL-1 group ; P < .0001 ) . -
pubmed
CONTEXT :
Nonalcoholic fatty liver disease (
NAFLD ) is the most common cause of
liver disease , affecting approximately 3 in 10 obese
children worldwide . -
pubmed
METHODS :
Patients who had
low back pain radiating to the leg , were preoperatively diagnosed with
cLDH by computed tomography and/or magnetic resonance imaging , and were treated with a surgical decompression procedure were studied . -
pubmed
The
patients developed few
postoperative complications and no
recurrence during 1 year of follow - up . -
pubmed
CONCLUSION : Our data suggest that the decompression approach is effective for management of
cLDH at least in the short term ( 1 year ) with respect to reducing
pain and improving
patient satisfaction with few complications . -
pubmed
We propose that appropriate
animal models of
human pregnancy complications must be established in the PEV field . -
pubmed
In this study , we generated
rat models of
septic shock induced by lipopolysaccharide . -
pubmed
METHODS : We performed a retrospective multicenter study including all
CD patients with a non - passable symptomatic UGT
stricture on endoscopy . -
pubmed
RESULTS : 60
CD patients with an
UGT stricture were included . -
pubmed
Rapid rehabilitation nursing improves clinical outcomes in postoperative
patients with colorectal
carcinoma : A protocol for randomized controlled trial . -
pubmed
Surgical treatment is widely performed in
patients with colorectal
carcinoma . -
pubmed
CONCLUSION : The research can offer a reliable basis for the effectiveness of a rapid recovery nursing program in
patients with
colorectal carcinoma . -
pubmed
SARS - CoV-2 - related rapid reorganization of an
epilepsy outpatient clinic from personal appointments to telemedicine services : A German single - center experience . -
pubmed
Overall , 9.2 % ( n = 10 ) of patients reported general supply problems due to
SARS - CoV-2 , and 28.4 % ( n = 31 ) reported
epilepsy - specific problems , most frequently related to prescriptions , or supply problems for antiseizure drugs (
ASDs ; 22.9 % , n = 25 ) . -
pubmed
In this article , we evaluated the structural
neuro - retinal abnormalities , especially the thickness in the
ganglion cell complex ( GCC ) , in
patients with
mitochondrial myopathy ,
encephalopathy ,
lactic acidosis and
stroke - like episodes (
MELAS ) . -
pubmed
The GCC thickness in
MELAS patients was significantly thinner than that in normal controls even when they had no history of transient
homonymous hemianopia . -
pubmed
In conclusion , OCT may be an effective tool to monitor and predict
disease progression in
MELAS patients . -
pubmed
Patients with suspected
sepsis were evaluated for
multi organ dysfunction . -
pubmed
Cell reaction of the interstitial tissue in the
aseptic inflammation areas was studied to determine the nonspecific reactivity of the organism in
patients with infiltrative
tuberculosis of the lungs . -
pubmed
Preoperative irradiation in the VASAG studies resulted in downstaging in terms of operative findings of lymph node involvement and was of survival benefit in those
patients have an AP resection for cure or palliation of rectal
cancer ( P less than 0.02 ) . -
pubmed
Principal features of the complex results include : double peaks in the time course of
convulsion thresholds ( Pc ) ; an early peak and a shoulder in the time course of pressures reversing anesthesia ( Pa ) ; far steeper dose - response curves for Pa than for Pc ; selectively greater anticonvulsant effect for
phenobarbital than for the other
barbiturates ; and enhancement of Pa with simultaneous
depression of Pc by
reserpine in
phenobarbital - pretreated
mice . -
pubmed
All
staphylococcal strains were inhibited by 4 micrograms of RP 59500 per ml , including multiply resistant
strains . -
pubmed
Thirty - six intensive care unit
patients , receiving aseptic or manually ( routine ) reconstituted enteral feeding formulas , were evaluated prospectively for the relationship of microbial involvement , gastric pH , and antimicrobial therapy to
diarrhea . -
pubmed
There were no significant direct associations between isolate category ( Gram - negative bacilli , Gram - positive cocci , Gram - negative cocci ,
yeast ) , gastric pH , or antimicrobials and
diarrhea . -
pubmed
However , two organisms ( Group D Enterococci and
yeast ) were indirectly implicated in some cases of
diarrhea . -
pubmed
Clinical deterioration in
patients with
idiopathic pulmonary fibrosis : causes and assessment . -
pubmed
In evaluating
clinical deterioration in
patients with
IPF , disease - associated complications and adverse effects of therapy should be distinguished from progressive
pulmonary fibrosis . -
pubmed
The cause of
clinical deterioration will alter the therapeutic intervention required and will influence
patient prognosis and duration of survival . -
pubmed
This article examines the causes of
clinical deterioration in
patients with
IPF and the diagnostic procedures for assessing disease - associated complications and staging
IPF progression . -
pubmed
Antibodies to
staphylococcal peptidoglycan and its peptide epitopes ,
teichoic acid , and
lipoteichoic acid in sera from blood donors and
patients with
staphylococcal infections . -
pubmed
Antibodies to the
staphylococcal antigens peptidoglycan ,
beta - ribitol teichoic acid , and
lipoteichoic acid , as well as to the peptidoglycan epitopes
L - Lys - D - Ala - D - Ala ,
L - Lys - D - Ala , and
pentaglycine , were found over a wide range of concentrations in sera from both blood donors and
patients with verified or suspected
staphylococcal infections . -
pubmed
A 30 - year old
man who for several years had been
hypertensive was admitted for attacks of
paroxysmal hypertension . -
pubmed
On the other hand , three
patients with in situ duct
carcinoma ( one comedo and two clinging type ) developed subsequent invasive
carcinoma . -
pubmed
Catecholamine activity in paraventricular hypothalamus after
hemorrhage in
cats . -
pubmed
Temporal changes in
catecholamine activity within the paraventricular nucleus ( PVN ) of the hypothalamus were assessed using in vivo voltammetry after moderate
hemorrhage in
chloralose - anesthetized
cats . -
pubmed
Because cloning cDNA copies of
HPV mRNAs recovered from
human lesions has met with only very limited success , the characterization of
HPV mRNAs has been problematic . -
pubmed
In comparisons among groups , the Tweed
patients generally exhibited the greatest lower
lip retraction . -
pubmed
[
Bacteroides fragilis meningitis . -
pubmed
In this study based on 2 personal cases and 23 cases from the literature the main clinical and therapeutic features of
meningitis caused by
Bacteroides fragilis are reviewed . -
pubmed
It is found the
PGE content in the gastric mucosa and plasma is increased in all
patients with
gastric cancer , especially with
signet ring cell carcinoma . -
pubmed
It is higher in the regional lymph node
metastasis than in the early
cancer , extensive
metastases and normal
subjects . -
pubmed
There is no significant difference in extensive
metastases , relapse free and normal
subjects . -
pubmed
inoculation of
tumor cells ( 5 - 10 x 10(4)/
mouse ) . -
pubmed
Sixty - three
patients presenting with the clinical problem of
renal outflow disorder were studied using
99mTc DTPA . -
pubmed
[ Survival of 17
patients with inoperable
bronchial cancer , treated with cytostatic drugs and radiation in minimal useful doses ] . -
pubmed
[ Contribution to the study of
philometrosis in
carp ] . -
pubmed
Canine
Filaroides osleri and
Filaroides milksi infection . -
pubmed
Tuberculosis should be suspected in immunosuppressed
patients suffering from
pyrexia of unknown origin , even when chest X - ray is normal . -
pubmed
Diet - dependent hyperplastic growth of adipose tissue in hypothalamic
obese rats . -
pubmed
Accelerated production of fat cells is often seen in dietary
obesity in
rats but not in
obesity occurring in response to damage to the medial area of the hypothalamus ( MH ) . -
pubmed
MH damage (
MHD ) was produced in
rats by either electric current or small knife cuts . -
pubmed
Fat cell production did not accelerate during the 1st 16 wk after
MHD in
rats fed only chow , but acceleration clearly occurred in
rats fed HFS during only 4 wk . -
pubmed
However , there was greater acceleration after MHD in HFS - fed
rats held to the same
weight gain as chow - fed
rats . -
pubmed
Rats allowed to freely eat HFS for 6 mo after MHD showed extremely large increases in
body weight and fat cell number . -
pubmed
The plateau in
body weight often seen in
rats fed only chow after
MHD did not occur . -
pubmed
These findings suggest that enlargement of fat cells and components of the diet act synergistically in the promotion of
adipocyte hyperplasia in adult
rats and also suggest that accelerated
weight gain after
MHD is not due to elevation of a set point for
body weight or body fat . -
pubmed
Heat - induced protection of
mice against
thermal death . -
pubmed
We used
C3H mice to investigate whether whole - body heating can be used as a conditioning treatment to induce protection of
mice against thermal
death from a subsequent heat treatment . -
pubmed
It is suggested that the myocardial ischaemic defence , as worked out by nature herself , in the diving seal has important implications for the treatment of acute
myocardial ischaemia in
man . -
pubmed
Masses of crystals , which were largely composed of
cholesteryl esters , were found in a
porcine aortic valvular bioprosthesis removed eight years after implantation in the mitral position in a
patient with
rheumatic mitral valvular stenosis . -
pubmed
These
cholesterol deposits are most likely derived from blood lipids ; however , they were not related to
hyperlipidemia , since the
patient had normal blood levels of
cholesterol and
triglycerides . -
pubmed
To assess the effects of radiation therapy on the specific red cell adherence test we have evaluated 33
patients who underwent cystectomy for
bladder cancer and in whom radiotherapy had been used . -
pubmed
These findings strongly suggest that 1 ) the specific red cell adherence test does remain negative after radiotherapy and 2 ) this test is a valuable prognosticator of the future likelihood of invasion in all
patients with
transitional cell carcinoma of the bladder . -
pubmed
Endothelium - dependent relaxation of small arteries from essential
hypertensive patients : mechanisms and comparison with normotensive subjects and with responses of vessels from spontaneously
hypertensive rats . -
pubmed
Impaired endothelium - dependent relaxation has been previously demonstrated in blood vessels of
hypertensive rats and in
humans with essential
hypertension . -
pubmed
The mechanisms involved in endothelium - dependent relaxation of
human arteries are unclear , and the potential generation of endothelium - derived contracting factor by endothelium in
human hypertension has not been established . -
pubmed
We investigated the effects of
acetylcholine on precontracted small arteries dissected from gluteal subcutaneous fat biopsies from normotensive
subjects and
subjects with borderline and mild essential
hypertension . -
pubmed
Vessels from normotensive
subjects and those from borderline
hypertensive patients , precontracted by
noradrenaline , were relaxed completely by
acetylcholine , whereas those from
patients with mild essential
hypertension relaxed slightly but significantly less , indicating that generation of endothelium - derived relaxing factor ( endothelium - derived
nitric oxide ) was only minimally reduced or that production of minor amounts of endothelium - derived contracting factor occurred in small arteries from these
hypertensive subjects . -
pubmed
This impairment of endothelium - dependent relaxation was not corrected by
indomethacin , which indicated that the contribution of endothelium - derived contracting factor , if any , was minimal in this subset of essential
hypertensive patients . -
pubmed
In contrast , mesenteric small arteries of adult spontaneously
hypertensive rats presented strong contractions in response to the higher concentrations of
acetylcholine , which were abolished by exposure to
indomethacin . -
pubmed
The authors studied 32 primary
uveal melanomas from 32
patients ( among these , 12 were rapidly metastasizing and 16 slowly metastasizing ) and 29
metastases from 19
patients . -
pubmed
From 13
patients the primary , as well as the metastatic ,
tumors were available . -
pubmed
Ventilatory and metabolic responses to
hypoxia in the echidna ,
Tachyglossus aculeatus . -
pubmed
We examined 29 eyes of 15
patients with
Harada disease using
ICG angiography . -
pubmed
In 3
patients , the area of
retinal detachment showed hypofluoresence in the late phase . -
pubmed
The studies using immunofluorescence test showed that the percentage of
HHV-6 - infected subjects was practically similar among blood donors , patients with
nasopharyngeal cancer ,
rheumatoid arthritis ,
hemophilia , and patients with transplanted kidney , varying from 34 % to 49 % . -
pubmed
A significantly higher per cent ( 66 % ) and higher antibody titres to
HHV-6 were detected in sera from patients with
hemoblastoses . -
pubmed
If we look at patients with correct diagnosis of
syncope ( 183
patients ) the mortality rate is 8.19 % ( if we consider those aged & gt ; 65 the rate is 17.44 % ) . -
pubmed
Operative treatment is indicated when conservative management for at least 6 months has been unsuccessful and
subluxation continues to occur during everyday activities , but it should never be instituted in
patients with
emotional disorders . -
pubmed
METHODS : One hundred thirty - four limbs of 123 unselected
patients who arrived in the outpatient clinic with residual or recurrent
varicose veins after undergoing an operation were included . -
pubmed
Prevalence of
Helicobacter pylori in
acromegalic patients during treatment with
octreotide . -
pubmed
In
acromegalic patients treated with
octreotide there is an increased incidence of
gallstones and possibly
gastritis . -
pubmed
OBJECTIVES : ( 1 ) To compare the seroprevalence of
Helicobacter pylori ( H. pylori ) infection , in
acromegalic patients treated with
octreotide to that in
patients given other treatment modalities . -
pubmed
PATIENTS : Three groups of
acromegalic patients were studied ; 35 ( 20 M ) had been treated with
octreotide , 17 ( 10 M ) with
bromocriptine and 19 ( 12 M ) had received no pharmacological intervention ( untreated , surgically treated or treated with radiotherapy ) . -
pubmed
To investigate this issue , the influence of either standard reoxygenation or transient
hyperoxia was studied on the consequences of severe
hypoxia in a model of cultured neurons isolated from the fetal
rat brain . -
pubmed
Animal models for the study of perinatal
hypoxic - ischemic encephalopathy : a critical analysis . -
pubmed
We critically evaluated various design features from 292
animal studies related to perinatal
hypoxic - ischemic encephalopathy (
HIE ) . -
pubmed
Rodents were the most frequently used
animals in
HIE research ( 26 % ) , followed by
piglets ( 23 % ) and
sheep ( 22 % ) . -
pubmed
While no single
animal model was found to be ideal for all
HIE research , some models were distinctly superior to others , depending upon the specific research question . -
pubmed
Experimental
infection of 10 juvenile
P. - pubmed
METHOD : We photodocumented the evolution of a full - thickness
macular hole in a
patient who refused surgery . -
pubmed
RESULTS : A 60 - year - old
woman , who had had difficulty reading for 3 months , was initially examined with a stage 1B
macular hole in her right eye that progressed to stage 2 over a 6 - month period and then to stage 3 , 2 years after initial examination . -
pubmed
Insulin resistance and increased fat mass ( FM ) are common in
human aging . -
pubmed
Histopathological and clinical studies indicate that areas of
choroidal ischemia often are seen near CNVs in
AMD patients . -
pubmed
Sexual dysfunction related to antihypertensive agents : results from the
animal model . -
pubmed
In order to delineate the direct drug effects from
vascular insufficiency inherent in
hypertensive states , the study was conducted on a normotensive
animal model . -
pubmed
The palliative procedure of partial gastrectomy , gastroenterostomy shunt and
trophic fistula was carried out 117
patients . -
pubmed
This review focuses on the developmental biology of
human bone marrow B - lineage cells , including perturbations that contribute to the origin and evolution of
B - lineage acute lymphoblastic leukemia and
primary immunodeficiency diseases characterized by
agammaglobulinemia . -
pubmed
The
triad of laboratory models that mimic the bone marrow microenvironment ,
immunodeficiency diseases with specific defects in B - cell development , and
B - lineage acute lymphoblastic leukemia can now be integrated to deepen our understanding of
human B - cell development . -
pubmed
Finally , we discuss their potential use for stratification of
patients with
acute coronary syndromes with respect to optimal treatment , resource - saving monitoring , and more precise prognostication . -
pubmed
OBJECTIVE : To determine the safety and efficacy of
glycopyrrolate in the treatment of
developmentally disabled children with
sialorrhea . -
pubmed
PATIENTS : Thirty - nine
children with both
developmental disabilities and excessive and bothersome
sialorrhea . -
pubmed
CONCLUSIONS :
Glycopyrrolate is effective in the control of excessive
sialorrhea in
children with
developmental disabilities . -
pubmed
Structural conformers produced during
malaria vaccine production in
yeast . -
pubmed
METHODS : From 1980 to 1997 , 477
patients were operated on for thoracic or intrathoracic
tuberculosis in Laennec Hospital , Paris ( 259 suffered
lung diseases ) . -
pubmed
Surgery was performed for a therapeutic purpose in 104
patients with sequelae , and in 10
patients with active
tuberculosis ( pneumonectomy , n = 19 ; pleuropneumonectomy , n = 19 ; lobectomy , n = 54 ; and segmentectomy , n = 22 ) . -
pubmed
Tumour enhancement with newly developed
Mn - metalloporphyrin (
HOP-9P ) in magnetic resonance imaging of
mice . -
pubmed
Stress of chronic food restriction attenuates the development of adjuvant
arthritis in male
Long Evans rats . -
pubmed
OBJECTIVE : To study the effect of the stress of chronic food restriction on the development of adjuvant
arthritis in Long Evans male
rats . -
pubmed
The
body weight of the
animals was recorded on day 0 , 3 , 7 , 11 , 15 and 18 of the disease . -
pubmed
Eosinophilic leukocytes accumulate in high numbers in the lungs of
asthmatic patients , and are believed to be important in the pathogenesis of
asthma . -
pubmed
METHODS :
CML cell line
K562 and fresh bone marrow cells from 6 untreated Ph+
CML patients were used for in vitro culture study . -
pubmed
Assessing
disturbed thinking and cognition using the Ego Impairment Index in older
schizophrenia patients :
paranoid vs. nonparanoid distinction . -
pubmed
RESULTS : Nonparanoid
schizophrenia patients demonstrated significantly greater impairment on the EII than their paranoid counterparts . -
pubmed
The EII performance of
paranoid patients was similar to normal comparison participants . -
pubmed
Furthermore , the
paranoid patients displayed better premorbid intellectual functioning , less negative symptoms , and better global cognitive performance than nonparanoid patients . -
pubmed
Rats were injected with lipopolysaccharide for induction of experimental gram - negative
sepsis . -
pubmed
Evidence from randomized trials now shows a survival advantage for the use of PBSC in
patients with advanced
leukaemia . -
pubmed
The same
GAGs were decreased in the skin of fasted
rats . -
pubmed
Relative contribution of
mucosal injury and
Helicobacter pylori in the development of
gastroduodenal lesions in
patients taking non - steroidal anti - inflammatory drugs . -
pubmed
METHODS : We used multivariate regression analyses of three large similar trials to identify factors that placed
patients at high risk of
ulcer development or
relapse . -
pubmed
We compared the efficacy of
omeprazole 20 mg daily ,
misoprostol 200 micro g twice daily , and
ranitidine 150 mg twice daily in preventing
ulcers and
erosions at different sites and in
patients who were
H pylori positive and negative . -
pubmed
RESULTS :
Patients with endoscopic lesions ( which healed ) initially were significantly more likely than those without to develop further
erosions or
ulcers during treatment ( rate ratio 2.12 , 1.07 - 4.17 ) . -
pubmed
This advantage was especially evident in
H pylori positive
patients receiving acid suppression ( 5.7 % v 16.6 % for
gastric ulcer with
omeprazole ) . -
pubmed
CONCLUSIONS :
Relapse of lesions in
patients taking NSAIDs was highly site and type specific and not adversely affected by H pylori status . -
pubmed
This strongly implies that local mucosal factors predispose to
ulcer development in
patients taking NSAIDs . -
pubmed
Trigeminal pain processing was studied in 14
patients with unilateral
migraine attacks and 14 age- and sex - matched
patients with comparable unilateral
headache from
frontal sinusitis . -
pubmed
Effects of
N - acetylcysteine on
myoglobinuric - acute renal failure in
rats . -
pubmed
This study was designed to determine the protective influence of
N - acetylcysteine (
NAC ) , a
hydroxyl radical scavenger , and treatment in an experimental model of
myoglobinuric -
ARF induced by intramuscular injection of hypertonic
glycerol in
rats . -
pubmed
The
rats were randomly distributed into five groups : Group 0 ( n = 10 ) , was assigned to receive 2mL saline ( 0,9 % ) intraperitoneally ( ip ) ; Group 1 ( n = 10 ) ,
NAC ip in a dose of 0 mg/100 g of
body weight 30 min before the intramuscular ( i m ) injection of 50 %
glycerol ( 10 mg / kg ) ; Group 2 ( n = 10 ) , received saline 0,9 % ip in a equivalent volume of
NAC in Group I before the i m injection of
glycerol ; Group 3 ( n = 10 ) , received
NAC ip in a dose of 10 mg/100 g after i m injection of
glycerol ; Group 4 ( n = 10 ) , saline 0,9 % ip in a equivalent volume of
NAC of the Group 3 after i m administration of
glycerol . -
pubmed
The results of this study suggests that ip administration of
NAC in
rats before or after
glycerol injection do not confer protection against
impairment of renal function under these conditions in this model of myoglobinuric -
ARF . -
pubmed
This increase coupled with the harsh side effects of some of the
cancer chemotherapies have led to the search for more natural biological products , especially those derived from
plant products , currently known as herbal medicine . -
pubmed
The objective of this study was to evaluate the effect(s ) of a novel water - soluble leaf extract of
Vernonia amygdalina ( VA ) on
human breast cancer cell DNA synthesis . -
pubmed
CASE : A 28 - year - old
woman was managed with total parenteral nutrition from 28 weeks ' gestation because of continuous
vomiting due to
esophageal hiatal hernia . -
pubmed
In specific pathologic circumstances , the
death program may be activated by various environmental factors such as exposure to toxic substances or
bacteria or deprivation of nutrients . -
pubmed
Tinea capitis due to
Trichophyton tonsurans ; incidence , diagnosis and epidemiology in the San Francisco Bay Region . -
pubmed
Eighty - five cases of
tinea capitis due to
T. - pubmed
[ I-131 - ROSE BENGAL TEST IN
PATIENTS WITH
CLONORCHIASIS ] . -
pubmed
METHODS : Six hundred and sixty - one clinical isolates of
Streptococcus pneumoniae , 936
Haemophilus influenzae and 421
Moraxella catarrhalis , collected in the winter of 1999 - 2000 by 20 laboratories in the UK and Eire from patients with presumed community - acquired lower
respiratory infections , were tested by the two methods . -
pubmed
OBJECTIVE : To investigate the effect of high dose
mifepristone and high dose
progesterone in the treatment of
patients with
endometrial carcinoma and to explore the possible mechanisms associating with them . -
pubmed
METHODS : Thirty untreated
patients diagnosed as
endometrial carcinoma through dilation and curettage of the uteri were divided into 3 groups at random . -
pubmed
Optimal management of
patients with
fulminant hepatic failure : targeting the brain . -
pubmed
Tumors in the negative control
animals regressed throughout the study while the
tumors in the soy flour - fed
animals remained basically the same size ( neither grew nor regressed ) . -
pubmed
Collectively , these findings suggest that for postmenopausal
women with
estrogen - dependent
breast cancer , the consumption of foods containing soy flour is more advisable than consuming
isoflavones in more purified forms . -
pubmed
The treatment of
patients with
acute myocardial infarction who present with the elevation of ST segment on electrocardiogram ( STEAMI ) is based on the need of re - establishing coronary blood flow through the occluded epicardial artery . -
pubmed
Histomorphometry of marrow megakaryocytes in experimental
uraemia in
rats . -
pubmed
Uraemic patients frequently demonstrate tendencies towards life - threatening
bleeding . -
pubmed
The aim of the study was a histomorphometric evaluation of marrow megakaryocytes in the course of experimental
uraemia in
rats . -
pubmed
Uraemia was induced by means of right nephrectomy and a partial removal of the left kidney cortex in
rats . -
pubmed
Among survivors , echocardiography , hemodynamic studies , and postmortem examination indicated that the WT and KO groups of infarcted
mice mounted a
hypertrophic response that was augmented in KO
mice . -
pubmed
In this study , we analyzed the mechanism by which
TZD inhibit growth of
human pancreatic carcinoma cell lines in order to evaluate the potential therapeutic use of these drugs in
pancreatic adenocarcinoma . -
pubmed
The distribution of
amphotericin B in lung tissue was studied in 18
patients with
primary or secondary lung cancer who underwent thoracotomy and pulmonary resection . -
pubmed
Long - term results of conservative management of
adnexal torsion in
children . -
pubmed
METHODS : The records of 14
girls with
ovarian torsion whose adnexal structures were preserved after detorsion were reviewed to evaluate the long - term results of conservative management . -
pubmed
Seven
patients had a benign
solitary cyst as an underlying cause for
adnexal torsion . -
pubmed
The intervention performed by open surgery in 9 and by laparoscopy in 5
patients included detorsion , simple
cyst aspiration , unroofing and/or cystectomy in 7
patients with
ovarian cysts , and oophoropexy in 9 of 14
patients . -
pubmed
CONCLUSIONS : Conservative management with untwisting the ovary and pexing both retained detorsed and contralateral ovaries especially in
idiopathic torsions should be considered in cases of
ovarian torsion in
children . -
pubmed
Human studies are needed to find out whether IN / OF have the potential to modulate systemic immunity in well - nourished
individuals and to lower the risk of diseases such as
colon cancer . -
pubmed
Ten
individuals with
cholangiocarcinoma were transplanted between 1996 and 2003 . -
pubmed
In conclusion , although early survival of
patients transplanted for incidental
cholangiocarcinoma appears good , intermediate- and long - term survival rates are not better than for individuals historically transplanted with known
cholangiocarcinoma . -
pubmed
Fluoroscopically guided balloon dilation for
patients with
esophageal stricture after radiation treatment . -
pubmed
PURPOSE : To evaluate the safety and clinical effectiveness of fluoroscopically guided balloon dilation in
patients with
esophageal stricture after radiation therapy ( RT ) . -
pubmed
MATERIALS AND METHODS : From April 1993 through December 2004 , fluoroscopically guided balloon dilation was performed in 15
patients with
esophageal strictures secondary to previous RT . -
pubmed
Two of 13
patients exhibited
recurrence of
dysphagia before 1 month after balloon dilation . -
pubmed
Among the 11
patients in whom clinical success was achieved , seven exhibited maintained initial improvement of
dysphagia until their last follow - up ( mean , 174 days ) and four exhibited
recurrence of
dysphagia after the first balloon dilation . -
pubmed
Dysphagia recurred 2 - 128 days ( mean , 67.2 d ) after the first balloon dilation in six of the 13
patients ( 46 % ) , who underwent further balloon dilation and/or stent placement . -
pubmed
Type 1 and 2
esophageal ruptures occurred after 12 dilations in nine
patients ; they were treated conservatively . -
pubmed
The open -
bite group ( OBG ) consisted of 18
patients ( 14
girls , 4
boys ) with a mean age of 14.5 + /- 2.7 years . -
pubmed
CONCLUSIONS : Compensatory tongue functions occur in
patients with anterior dental
open bites . -
pubmed
During the 2002 - 2003 period , there were 14,023 laboratory - confirmed
human cases of
WNV in 45 states and 541 associated
deaths . -
pubmed
Larger studies of more agricultural centers are warranted to determine which environmental factors increase the risk of
human infection and how these
infections can be prevented . -
pubmed
In five
Beagle bitches
hypersomatotropism was induced by administration of
MPA for over 1 year . -
pubmed
In conclusion ,
aglepristone can be used successfully to treat
dogs with
progestin - induced
hypersomatotropism . -
pubmed
OBJECTIVE : To describe possible correlations between incidence of
postpartum depression and the following patient characteristics : age , breastfeeding status ,
tobacco use , marital status , history of
depression , and method of delivery . -
pubmed
To facilitate prophylactic
patient education and intervention strategies , a larger study is recommended to determine risk factors for
postpartum depression . -
pubmed
Clinical and dynamic ( gait - related ) measures thought to be associated with pelvic retraction were investigated in
patients with
cerebral palsy . -
pubmed
Gait laboratory data of 233
patients with
cerebral palsy were studied retrospectively . -
pubmed
A
monkey demonstrator opened the
AF , showing alternative methods to 2 groups of cage mates . -
pubmed
Attention - deficit / hyperactivity disorder (
ADHD ) is the most common
neurobehavioral disorder affecting school - age
children . -
pubmed
For school - age
children , this necessitates administering medication during school hours , creating the potential for
embarrassment and noncompliance . -
pubmed
Its expression is down - regulated during active
human Crohn ' s disease , experimental
colitis in vivo , and oxidative stress in vitro . -
pubmed
A 49 - year - old
man , who had been diagnosed with
chronic lymphocytic leukemia (
CLL ) in 2002 , had a normal karyotype in his bone marrow . -
pubmed
Human papillomavirus (
HPV ) is considered to be a necessary but not sufficient cause for
cervical cancer . -
pubmed
The early history of
plasma cell tumors in
mice , 1954 - 1976 . -
pubmed
Plasma cell tumors ( PCTs ) in
mice became available at an exciting period in immunology when many scientists and laboratories were occupied with how to explain the genetic basis of antibody diversity as well as antibody structure itself . -
pubmed
An unlimited source of PCTs in an inbred
strain of
mice became a useful adjunct in these efforts . -
pubmed
The effect of pressure - overloading distance on left ventricular ( LV ) function in
patients with
congenital aortic coarctation and
aortic stenosis (
AS ) was investigated . -
pubmed
The World Health Organization reported that the
death rate attributable to
tobacco was 6.0 % worldwide and 9.2 % in China in 1990 . -
pubmed
Molecular classification of
patients with
malignant melanoma for new therapeutic strategies . -
pubmed
We can thus hope that research on the GSCs in
Drosophila will benefit therapeutic approaches to
human degenerative diseases . -
pubmed
Human Breast Cancer and the Milk Factor . -
pubmed
METHODS : We present a systematic review of reports describing the use of
piracetam and its derivatives in
animal models of
focal ischaemia , where the outcome was measured as an
infarct size or neurological score ( Der Simonian and Laird random effects meta - analysis ) . -
pubmed
RESULTS : Only 2 studies , published 10 years after the first clinical trial of
piracetam had been initiated , described its efficacy in
animal models of
stroke . -
pubmed
Cytotoxicity of
1,2 - diacetylbenzene in
human neuroblastoma SHSY5Y cells is mediated by oxidative stress . -
pubmed
Environmental organic solvent metabolite ,
1,2 - diacetylbenzene (
1,2 - DAB ) , treated
rats develop
limb weakness with
neuropathological damage in both the central and peripheral nervous systems . -
pubmed
In this experiment , we examined the relevance of
1,2 - DAB - induced
toxicity to increased oxidative stress using
human dopaminergic
neuroblastoma SHSY5Y cells . -
pubmed
A diet low in fat and high in
vegetables , fruit , and fiber following
breast cancer treatment did not reduce new
breast cancer events . -
pubmed
These agents have been shown to reduce
BC incidence in nonpregnant
rats . -
pubmed
Enzymatic isolation of
Lacazia loboi cells from
skin lesions of
lobomycosis . -
pubmed
Lacazia loboi is the etiologic agent of
Jorge Lobo ' s disease , a
cutaneous and subcutaneous mycosis endemic to Latin America tropical regions and characterized by chronic nodular or
keloidal lesions which develop after traumatic events . -
pubmed
, Nature 415(6871):530 - 536 , 2002 ) may improve the selection of
lymph node - negative breast cancer patients for adjuvant systemic therapy . -
pubmed
Optimal validation of prognostic classifiers is of great importance and we therefore wished to evaluate the prognostic value of the 70 - gene prognosis signature in a series of relatively recently diagnosed lymph node negative
breast cancer patients . -
pubmed
METHODS : We evaluated the 70 - gene prognosis signature in an independent representative series of
patients with invasive
breast cancer ( N = 123 ; & lt;55 years ; pT1 - 2N0 ; diagnosed between 1996 and 1999 ; median follow - up 5.8 years ) by classifying these patients as having a good or poor prognosis signature . -
pubmed
CONCLUSION : The 70 - gene prognosis signature is also an independent prognostic factor in node - negative
breast cancer patients for
women diagnosed in recent years . -
pubmed
The derivation of ES cells is poorly understood and varies in efficiency between different
strains of
mice . -
pubmed
Can the principle of " LYFT " help objectively in timing renal transplantation therapy for the
CKD patients ? -
pubmed
We carried out a cross sectional study of 630 patients with
tuberculosis and identified 100
patients with
spinal involvement in the three hospitals . -
pubmed
Out of the 100
patients with
spinal tuberculosis , 58 % were male and 42 % were female . -
pubmed
In this here , we discuss about clinical and histopathological findings in
patients with
spinal tuberculosis . -
pubmed
INTRODUCTION :
Carcinoma of the breast is the most common
malignancy of
women in Karachi . -
pubmed
CONCLUSIONS : Given the current surgical care of
patients with
mutilated hand injuries , HISS determined at the time of
injury can adequately predict functional outcome and return to work status . -
pubmed
Laboratory investigations in
animals suggest that concomitant
hypoxemia hinders resuscitation attempts , and that
epinephrine and
vasopressin are more likely to be associated with poor outcomes than lipid . -
pubmed
We report on 151 consecutive
patients who had wire - free fixation of
jaw fractures , and outline the value of a system of plastic anchorage points applied to individual teeth in both jaws that allows for wire - free IMF when they are linked by elastics ( Rapid IMF , Synthes , PA , USA ) . -
pubmed
Using an occlusographic analysis based on angular mandibular movement in a large
patient cohort , we were able to demonstrate and quantify , for the first time , the
relapse . -
pubmed
alata in a
rat model of
polycystic ovary syndrome . -
pubmed
alata ( LPva)-a Malaysian herb thought to have phytoestrogenic effects - has shown promise in reducing body
weight gain in ovariectomized
rats . -
pubmed
In this study , we investigated the effect of LPva on body composition and metabolic features in female
rats treated continuously with
dihydrotestosterone , starting before puberty , to induce
PCOS . -
pubmed
MATERIAL AND METHODS : At 9 weeks of age , the
PCOS rats were randomly subdivided into two groups ; PCOS LPva and PCOS control . -
pubmed
PCOS LPva
rats received a daily oral dose of LPva ( 50mg / kg
body weight ) , dissolved in 1 ml of deionised water , for 4 - 5 weeks . -
pubmed
Avian influenza virus isolates from wild birds replicate and cause disease in a
mouse model of
infection . -
pubmed
The direct transmission of highly pathogenic
avian influenza ( HPAI ) viruses to
humans in Eurasia and subsequent disease has sparked research efforts leading to better understanding of HPAI virus transmission and pathogenicity in mammals . -
pubmed
These findings demonstrate the potential of wild
avian influenza viruses to directly infect
mice without prior adaptation and support their potential role in emergence of
pandemic influenza . -
pubmed
The first
patient ( case 1 ) relapsed after double - unit cord blood transplantation ; there was no evidence of
relapse in the second
patient ( case 2 ) after allogenic peripheral blood stem cell transplantation . -
pubmed
Our aim in this study was to determine the presence of complications ,
pseudarthrosis , non - union , and
infection using combined in situ local autograft bone and freeze - dried cancellous allograft bone in
patients undergoing posterior spinal fusion for the treatment of adolescent
idiopathic scoliosis . -
pubmed
METHODS : A combination of in situ local autograft bone and freeze - dried cancellous allograft blocks were used in 50 consecutive
patients with
adolescent idiopathic scoliosis treated by posterior fusion and Moss Miami pedicle screw instrumentation . -
pubmed
These
avian leiomyomas have been proposed as a model for similar
tumours in other species . -
pubmed
Effectiveness of VIA , Pap , and
HPV DNA testing in a
cervical cancer screening program in a peri - urban community in Andhra Pradesh , India . -
pubmed
BACKGROUND : While many studies have compared the efficacy of Pap cytology , visual inspection with
acetic acid (
VIA ) and
human papillomavirus (
HPV ) DNA assays for the detection
cervical intraepithelial neoplasia and
cancer , few have evaluated the program effectiveness . -
pubmed
The use of a less invasive and more user - friendly primary screening strategy ( such as self - collected swabs for
HPV DNA testing ) may be required to achieve the coverage necessary for effective reduction in
cervical cancer mortality . -
pubmed
[ One - stage anteroposterior hemi - vertebra resection and segmental internal fixation for young
children with
congenital scoliosis ] . -
pubmed
OBJECTIVE : to discuss the feasibility and efficacy of one - stage anteroposterior hemi - vertebra resection and segmental internal fixation for young
children with
congenital scoliosis . -
pubmed
CONCLUSION : the procedure of one - stage anteroposterior hemi - vertebra resection and segmental internal fixation is a safe and effective treatment for
scoliosis by
congenital hemi - vertebra in young
children . -
pubmed
METHODS : We used a cross - sectional nationally representative survey of 950 primary care physicians familiar with
human papillomavirus (
HPV ) testing to assess adherence to management guidelines by analyzing responses to two clinical vignettes of a 35 - year - old woman who had Pap and
HPV tests results : 1 ) discordant ( normal Pap and positive HPV ) or 2 ) mildly abnormal (
atypical squamous cells of undetermined significance Pap and negative
HPV ) . -
pubmed
Insights into gene expression profiling of natural resistance to
coccidiosis in contrasting
chicken lines . -
pubmed
Coccidiosis is a
parasitic disease with major economic impact , one of whose main causative agents is
Eimeria tenella . -
pubmed
BACKGROUND : Our goal was to create a clinically relevant large
animal model of
pulmonary hypertension to serve as a platform allowing preclinical risk / benefit assessment of innovative therapies including artificial lung prototypes . -
pubmed
RESULTS : All
animals survived the study and developed
pulmonary hypertension by wk 5 . -
pubmed
CONCLUSIONS : We conclude that our 8 - wk model of continuous air embolization produces reliable , chronic
pulmonary hypertension in
sheep with sustained hemodynamic changes , significant
pulmonary vascular remodeling , and
right ventricle hypertrophy . -
pubmed
A 92 - year - old Japanese
woman consulted to our hospital because of
right nasal obstruction and
epistaxis . -
pubmed
The
tumor was reduced in size by local resection and chemotherapy ( Darthmose regimen :
dacarbazine ,
carmustine ,
cisplatine , and
tamoxifen ) , and the
patient is now alive and free from
metastasis 9 months after the first manifestation . -
pubmed
METHODS : We prospectively analyzed data on all
patients who underwent carotid endarterectomies for symptomatic
carotid stenosis between May 12 , 2008 , and May 31 , 2011 , with records in the Swedish Vascular Registry ( Swedvasc ) . -
pubmed
RESULTS : We analyzed data for 2596
patients and found that the combined mortality and
stroke rate for
patients treated 0 to 2 days after qualifying event was 11.5 % ( 17 of 148 ) versus 3.6 % ( 29 of 804 ) , 4.0 % ( 27 of 677 ) , and 5.4 % ( 52 of 967 ) for the groups treated at 3 to 7 days , 8 to 14 days , and 15 to 180 days , respectively . -
pubmed
CONCLUSIONS : In this study of
patients treated for symptomatic
carotid disease , it was safe to perform surgery as early as Day 3 after a qualifying neurological event in contrast to
patients treated within 0 to 2 days , which has a significantly increased perioperative risk . -
pubmed
Lower physical activity is a strong predictor of cardiovascular events in elderly
patients with
type 2 diabetes mellitus beyond traditional risk factors : the Japanese Elderly Diabetes Intervention Trial . -
pubmed
METHODS : A total of 716 specimens from
gastric cancer patients who underwent curative gastrectomy between 1996 and 2003 at Zhejiang Provincial People 's Hospital were reviewed . -
pubmed
RESULTS : The overall cumulative 5 - year survival rate of
EGC patients was 88.92 % . -
pubmed
Patients with
tumors larger than 2 cm in diameters , with depth of
tumor invasion to the submucosa , and with positive lymphatic or nerve involvement were also inclined to have poorer survival performances . -
pubmed
Multivariate analysis identified lymphatic invasion and
tumor size as independent prognosis factors related to survival in
EGC patients . -
pubmed
CONCLUSIONS : Careful planning is required in
EGC patients at high risk of lymph node
metastases . -
pubmed
Infection of the subcutaneous tunnel as a major complication was found in 1
pig . -
pubmed
Usefulness of diffusion tensor imaging in
patients who showed sustained unexplainable clinical symptom of
torticollis . -
pubmed
We evaluated 10
patients with sustained
torticollis and 12 age - matched control subjects . -
pubmed
All
patients showed no specific
fibromatosis coli findings on neck sonography . -
pubmed
All
patients showed only
torticollis symptom but no definite
hemiplegic pattern on their extremities at initial evaluation . -
pubmed
The results of
DTT corresponded to the delayed
hemiplegic symptoms , which were found in the
patients at second evaluation . -
pubmed
AA and
AD values between
patients and control group were significantly different . -
pubmed
DTI may be an additional technique for the early detection of
hemiplegia in
patients with sustained symptoms of unexplainable
postural torticollis . -
pubmed
Our objective was to describe the prevalence and features of
cognitive impairment in a large cohort of
patients with this
rare disease ( n = 57 ; mean age = 45 ) and to explore the relations between
memory impairment and
depression . -
pubmed
Patients with
mastocytosis presented high levels of
cognitive impairment ( memory and/or attention ) ( n = 22 ; 38.6 % ) . -
pubmed
In conclusion ,
immediate auditory memory and attention impairment in
mastocytosis are frequent , even in young
individuals , and are not consecutive to
depression . -
pubmed
Ehrlichia ruminantium , the etiologic agent of the economically important
disease heartwater , is an obligate intracellular bacterium transmitted by ticks of the genus Amblyomma , particularly
A. - pubmed
ruminantium
infection in the tick vector ,
A. - pubmed
ruminantium DNA in 142 ( 28.4 % ) of the 500 ticks with a higher
infection rate ( 47/115 ; 40.9 % ) observed in ticks from SDR and 24.7 % ( 95/385 ) of ticks collected from
cattle at UFR . -
pubmed
Neuropsychiatric features of a cohort of
patients with
systemic lupus erythematosus . -
pubmed
NPSLE was identified in 22
patients . -
pubmed
The series of
patients was further analysed according to the presence of
antiphospholipid syndrome (
APS ) . -
pubmed
While there is no ambiguity in the literature about the urgency of care for
patients with
MSCC , the effect of timing of surgical intervention has not been investigated in detail . -
pubmed
The objective of our study was to investigate whether or not the ' timing of surgery ' is an important factor in survival and neurological outcome in
patients with
MSCC . -
pubmed
METHODS : All
patients with
MSCC presenting to our unit from October 2005 to March 2010 were included in this study . -
pubmed
RESULTS :
Patients ' age , gender , revised Tokuhashi score , level of spinal
metastasis and primary
tumour type were not significantly different between the three groups . -
pubmed
Furthermore , earlier surgical treatment within 48 h in
patients with
MSCC resulted in significantly better neurological outcome . -
pubmed
[ Differential characteristics of the efficacy and tolerability of second - generation antipsychotics in the treatment of
psychotic disorders in
children and adolescents ] . -
pubmed
Over the last few years , there has been a marked increase in the prescription of second - generation antipsychotics ( SGA ) for the treatment of
psychotic disorders and other
psychiatric conditions in
children and adolescents . -
pubmed
Patients with adequate
urea clearance and delivered dialysis session & gt;=240 and & lt;240 minutes were pair - matched on interdialytic
weight gain ( n=1794 ) , and patients with
weight gain & lt;=3 and & gt;3 kg were pair - matched on session length ( n=2114 ) ; mortality associations were estimated separately . -
pubmed
A prospective randomized study was performed of 78 eyes in primary
pterygium patients treated by excision . -
pubmed
Primary
pterygium patients were randomly assigned to
ethanol group ( 38 eyes given intraoperative
ethanol ) or
mitomycin - c (
MMC ) group ( 40 eyes given intraoperative
MMC ) . -
pubmed
It suggests this regimen as an alternative for the treatment of
pterygium , especially for those
patients of high risk group for
MMC treatment complications . -
pubmed
Dynamics of milk leukocytes in response to a biological response modifier during
bovine subclinical
mastitis . -
pubmed
The objective of this study was to evaluate the dynamics of milk leukocyte in response to intramammary infusion of a biological response modifier ( BRM ) prepared from
Nocardia globerula during
bovine subclinical
mastitis (
SCM ) . -
pubmed
SUMMARY : Diagnosis and treatment of
patients with severe
ocular allergy is a challenge for ophthalmologists due to the long - term corneal complications and the potential side - effects of topical corticosteroids that may induce
cataract formation and
glaucoma , and impair vision permanently . -
pubmed
The G+C content of the genomic DNA of
strain PB156(T ) was 61.7 mol% . -
pubmed
The type
strain is
PB156(T ) ( = KCTC 32477(T ) = JCM 19433(T ) ) . -
pubmed
MATERIALS AND METHODS : Two - hundred and fifty one
patients admitted within 24 h of onset of
stroke symptoms into the
stroke unit of a tertiary care hospital were followed up for
convulsive seizure(s ) within 7 days of admission and for disease outcome in 42 days . -
pubmed
Coincidental
metabolic syndrome increases the risk of
liver fibrosis progression in
patients with
chronic hepatitis B -- a prospective cohort study with paired transient elastography examinations . -
pubmed
METHODS : A total of 1466
CHB patients underwent liver stiffness measurement ( LSM ) by transient elastography in 2006 - 2008 ; 663
patients remained treatment - naive and had second LSM in 2010 - 2012 . -
pubmed
Metabolic syndrome was diagnosed in 80 ( 12 % ) and 142 ( 21 % )
patients at baseline and follow - up visit , respectively ; 84 ( 13 % ) and 22 ( 3 % ) patients had coincidental and resolved
metabolic syndrome respectively . -
pubmed
After an interval of 44 + - 7 months , 107 ( 16 % )
patients developed
liver fibrosis progression . -
pubmed
CONCLUSION : Coincidental
metabolic syndrome increases the risk of
liver fibrosis progression in
patients with
chronic hepatitis B infection , independent of viral load and
hepatitis activity . -
pubmed
Budesonide loaded nanoparticles with pH - sensitive coating for improved mucosal targeting in
mouse models of
inflammatory bowel diseases . -
pubmed
The efficacy of both coated and plain nanoparticle formulations was assessed in different acute and chronic
colitis mouse models , also in comparison to an aqueous solution of the drug . -
pubmed
Prevalence of the rs12979860 CC genotype among genotype 1
HCV infected patients of Asian ethnicity was 69.48 % ( 95 % CI : 65.20 - 73.77 ) , which was significantly higher than its prevalence [ 33.27 % ( 95 % CI : 28.88 - 37.67 ) ] in the Caucasian genotype 1
HCV infected patients . -
pubmed
Small cell carcinoma of the prostate (
PSCC ) is a highly aggressive
malignancy that often develops in
patients previously treated with hormonal therapy for metastatic
prostatic acinar adenocarcinoma . -
pubmed
These findings suggest a key role for blood monocytes in the rapid onset of
fever in animals and
humans exposed to
bacterial products and some novel adjuvants . -
pubmed
Death and transfiguration in static
Staphylococcus epidermidis cultures . -
pubmed
However , when several
Staphylococcus epidermidis strains were cultivated in static liquid cultures , macroscopic aggregates were seen floating within the broth and also sedimented at the test tube bottom . -
pubmed
These observations indicate that some
strains of
Staphylococcus epidermidis are able to build highly sophisticated structures , in which a subpopulation undergoes cell lysis , presumably to provide continued access to nutrients in a nutrient - limited environment , whilst maintaining structural integrity . -
pubmed
Two novel toxin variants revealed by whole - genome sequencing of 175
Clostridium botulinum type E
strains . -
pubmed
We sequenced 175
Clostridium botulinum type E
strains isolated from food , clinical , and environmental sources from northern Canada and analyzed their botulinum neurotoxin ( bont ) coding sequences ( CDSs ) . -
pubmed
The present study aims to characterize the chemical nature of
avocado constituents with inhibitory effects on
platelet aggregation . -
pubmed
From these results ,
avocado may be referred to as a functional food containing
acetogenin compounds that inhibit
platelet aggregation with a potential preventive effect on
thrombus formation , such as those that occur in
ischaemic diseases . -
pubmed
Establishment of a
murine graft - versus - myeloma model using allogeneic stem cell transplantation . -
pubmed
We observed a GvM effect in 94 % of the allogeneic transplanted
mice , as the luciferase signal completely disappeared after transplantation , whereas all the autologous transplanted
mice showed
myeloma progression . -
pubmed
In addition , the treated
mice also displayed chronic
GvHD symptoms . -
pubmed
CONCLUSIONS : We successfully established an immunocompetent
murine model of
graft - versus - myeloma . -
pubmed
The protective effect of
caffeic acid on global
cerebral ischemia -
reperfusion injury in
rats . -
pubmed
The aim of this study was to investigate the effect of
caffeic acid on global
cerebral ischemia -
reperfusion injury in
rats . -
pubmed
Caffeic acid markedly reduced the escape latency , relieved hippocampal neurons
injury and increased neuron count compared with those of I / R non - treated
rat . -
pubmed
The results of the study suggest that
caffeic acid has a significant protective effect on global
cerebral ischemia -
reperfusion injury in
rats . -
pubmed
In
cattle , this
neoplasm is very rare and to date has only been described three times . -
pubmed
This report provides the first sonographic images of
bovine testicular yolk sac tumor as well as the first information about hormone levels in
calves with this
neoplasm . -
pubmed
We report a case of a
patient with
angioimmunoblastic T - cell lymphoma presenting initially with
pruritus and
saggy skin , which later progressed into
erythroderma despite chemotherapy ; the disease eventually resolved with autologous stem cell transplant . -
pubmed
We report a 64 - year - old
woman morphologically diagnosed with
chronic myelogenous leukemia in the chronic phase . -
pubmed
AREAS COVERED : This review covers the preclinical and clinical studies of
erlotonib as it relates to its use in the treatment of
NSCLC patients with
BM . -
pubmed
Obesity - linked type 2 diabetes is one of the paramount causes of morbidity and mortality worldwide , posing a major threat on
human health , productivity , and quality of life . -
pubmed
It has been suggested that one in five riders will be injured due to a fall from a
horse , resulting in severe
head or torso injuries . -
pubmed
The article concludes with a practical application of WHS to prevent
horse - related
injury by discussing effective evidence - based guidelines and regulatory monitoring for equestrian sectors . -
pubmed
It suggests that the WHS framework has significant potential not only to reduce the occurrence and likelihood of
horse - related
human accident and
injury , but to enable systematic accident analysis and investigation of horse - related adverse events . -
pubmed
Cystic Fibrosis Isolates of
Pseudomonas aeruginosa Retain
Iron - Regulated Antimicrobial Activity against
Staphylococcus aureus through the Action of Multiple
Alkylquinolones . -
pubmed
Early
infection of the CF lung with
Staphylococcus aureus is common , while
Pseudomonas aeruginosa becomes dominant as disease progresses . -
pubmed
Compensatory increases in
HHQ were also observed in
PQS - deficient CF isolates , which also retained the ability to mediate
iron - regulated antimicrobial activity against
S. - pubmed
CONCLUSIONS : A vascular risk assessment and neurological examination are adequate for risk stratification of
ischemia in the dizzy
patient and should remain the standard evaluation . -
pubmed
Our study presents a case report of a
patient with a
retroperitoneal leiomyosarcoma that was radically ( R0 ) removed . -
pubmed
Articular cartilage degeneration causes
pain and reduces the mobility of millions of
people annually . -
pubmed
RESULTS : Twenty - one of 2423
patients who underwent ERCP had a
perforation ( 0.9 % ) . -
pubmed
RATIONALE :
Ascariasis is an endemic
parasitic disease caused by
Ascaris lumbricoides , which severely burdens the healthcare system as well as harms the personal life quality , especially among less developed regions . -
pubmed
Concurrent administration of
thyroxine and
donepezil induces plastic changes in the prefrontal cortex of adult
hypothyroid rats . -
pubmed
Adding 0.05 %
propylthiouracil to
rats ' drinking water induced a
hypothyroid rat model . -
pubmed
CONTEXT : Partner services are a broad array of services that should be offered to persons with
human immunodeficiency virus (
HIV ) and that are based on a process through which HIV - infected persons are interviewed to elicit information about their sex and needle - sharing partners . -
pubmed
Human immunodeficiency virus testing of partners can result in a high yield of newly diagnosed
HIV positivity , but despite this yield and the benefits of partners knowing their exposures and HIV status , partner services are often not conducted . -
pubmed
METHODS : From January 2008 to November 2015 , two hundred and forty - five consecutive
patients with an average age of 36.2 + - 10.9 years ( range , 17 - 66 years ) satisfying the Modified New York Criteria for
AS from a single institution were enrolled . -
pubmed
Coronary artery bypass grafting in
patients with severe
chronic kidney disease : a propensity score - weighted analysis on the impact of on - pump versus off - pump strategies . -
pubmed
OBJECTIVES : The optimal surgical strategy regarding the use of cardiopulmonary bypass during coronary artery bypass grafting in
patients with severe
chronic kidney disease remains controversial . -
pubmed
METHODS : Between 1997 and 2015 , we identified 321 consecutive
patients with severe
chronic kidney disease ( Stage 4 or 5 ) based on the National Kidney Foundation Classification ( estimated
glomerular filtration rate & lt;30 ml / min/1.73 m2 ) . -
pubmed
CONCLUSIONS : The on - pump strategy for
patients with severe
chronic kidney disease was associated with a significantly higher risk of mortality and morbidities , which is particularly attributable to a greater risk of cardiopulmonary bypass use in the early postoperative period . -
pubmed
CDDO - EA was evaluated in vivo as a monotherapy as well as adjunctive therapy with parenteral
artesunate in the
Plasmodium berghei strain ANKA experimental
cerebral malaria ( ECM ) model . -
pubmed
Microfracture augmented by autologous bone marrow concentrate ( BMC ) was previously shown to yield structurally superior cartilage repairs in an
equine model compared with
microfracture alone . -
pubmed
CONCLUSIONS : When BMC was applied directly to critical - sized , full - thickness chondral defects in an
equine model , the cartilage repair results were similar to those of
microfracture . -
pubmed
Using the
chronic kidney disease guidelines to evaluate the renal safety of
tenofovir disoproxil fumarate in
hepatitis B patients . -
pubmed
BACKGROUND :
Renal dysfunction remains an issue in
tenofovir disoproxil fumarate (
TDF ) for
chronic hepatitis B (
CHB )
patients . -
pubmed
METHODS : We retrospectively recruited
CHB patients who received either
TDF or
entecavir (
ETV ) monotherapy from January 2008 to August 2015 . -
pubmed
After excluding confounding conditions , 253
patients who received
TDF were randomly matched 1:2 with 506
patients who received
ETV through the propensity scores , which consisted of age , gender ,
cirrhosis ,
chronic kidney disease (
CKD ) and estimated
glomerular filtration rate ( eGFR ) . -
pubmed
Methods : A prospective , observational study was carried out on 25 wrists of 20 consecutive
patients with
carpal tunnel syndrome , confirmed by the American Association of Neuromuscular and Electrodiagnostic Medicine criteria , which includes clinical history , symptoms , and evidence of slowing of distal median nerve conduction . -
pubmed
[ Prognostic significance of the total
ischemic time in
patients with ST - elevation
myocardial infarction ] . -
pubmed
METHOD : From 1 January 2014 all
patients with
myocardial infarction were recorded by law in an on - line database of the Hungarian
Myocardial Infarction Registry . -
pubmed
Between 1 January 2014 and 31 March 2016 , 27 157
patients with 28 408
myocardial infarction events were recorded . -
pubmed
To investigate TIT , 7146
STEMI patients were selected who were treated with percutaneous coronary intervention ( PCI ) within 24 hours of the beginning of the complaint and all of its components were known . -
pubmed
The TIT is an independent prognostic factor , so reducing this time can improve the long - term prognosis of
patients with ST - elevation
myocardial infarction . -
pubmed
Sulthiame add - on therapy in
children with
Lennox - Gastaut syndrome : A study of 44
patients . -
pubmed
PURPOSE : The aim of this study was to evaluate efficacy and tolerability of
sulthiame as an add - on treatment in 44
patients with
Lennox - Gastaut syndrome (
LGS ) refractory to other antiepileptic drugs and/or non - pharmacological treatment . -
pubmed
METHODS :
Patients were selected according to the following criteria : ( 1 ) age 4 years or older , ( 2 ) a diagnosis of
LGS refractory to at least four previous antiepileptic drugs , alone or in combination . -
pubmed
RESULTS : Twenty - seven of 44
patients ( 61 % ) who received
sulthiame as add - on therapy had a greater than 50 %
seizure decrease after a mean follow - up period of 20 months . -
pubmed
Complete
seizure freedom was achieved in one
patient ( 2 % ) . -
pubmed
Four
patients ( 9 % ) had a 25 - 50 %
seizure decrease , while
seizure frequency remained unchanged in 12 ( 25 % ) , and was increased in one ( 2 % ) . -
pubmed
Hyperpnoea and
dyspnoea were observed in four
patients , and
nausea ,
drowsiness , and
headache were seen in one
patient each ; however , these manifestations were transient and discontinuation of
sulthiame was not necessary . -
pubmed
Two other
patients had
decreased appetite ,
skin rash , and
irritability . -
pubmed
CONCLUSION :
Sulthiame as an adjunctive therapy achieved a more than 50 %
seizure reduction in 27 of 44
patients with
LGS with only mild or moderate adverse effects . -
pubmed
Anti -
atherosclerosis of
oligomeric proanthocyanidins from
Rhodiola rosea on
rat model via hypolipemic , antioxidant , anti - inflammatory activities together with regulation of endothelial function . -
pubmed
Human papillomavirus testing may detect
cervical precancer better than Papanicolaou testing . -
pubmed
In - hospital mortality was high in
syncope patients with
pulmonary embolism (
PE , 13.0 % ) ,
pneumonia ( 12.8 % ) ,
myocardial infarction (
MI , 9.7 % ) and
stroke ( 8.5 % ) . -
pubmed
Integrated miRNA and mRNA expression analysis uncovers drug targets in
laryngeal squamous cell carcinoma patients . -
pubmed
Little is known about
norovirus infections in most non -
human hosts , but the close genetic relatedness between some animal and
human noroviruses coupled with lack of understanding where newly appearing
human norovirus genotypes and variants are emerging from has led to the hypothesis that norovirus may not be host restricted and might be able to jump the species barrier . -
pubmed
There is no cure for
SLE , but current standard pharmacotherapies can improve disease prognosis in most
patients . -
pubmed
All adult
patients identified in the Nanjing database with an
SLE Disease Activity Index ( SLEDAI ) score & gt;= 8 at baseline that had undergone MSC transplant and who had at least 1 year of follow - up after one or two successive intravenous injections of allogeneic BM-/UC - MSCs ( 1 million / kg ) were analyzed . -
pubmed
Women with
adnexal lesions and/or persistently elevated risk were clinically assessed and underwent surgery or follow - up for a median of 10.9 years . -
pubmed
Area under the curve and sensitivity for diagnosing
ovarian cancer of multiple penalized logistic regression models incorporating logCA125 , log
human epididymis 4 , age , and simple ultrasound features of the adnexal mass were compared . -
pubmed
RESULTS : Of 1590 ( 158 multimodal , 1432 ultrasound )
women with adnexal masses , 78 were diagnosed with
ovarian cancer ( 48 invasive epithelial ovarian , 14 type I , 34 type II ; 24 borderline epithelial ; 6 nonepithelial ) within 1 year of scan . -
pubmed
Isoquinolinamine FX-9 Exhibits Anti - Mitotic Activity in
Human and
Canine Prostate Carcinoma Cell Lines . -
pubmed
Current therapies are insufficient for
metastatic prostate cancer (
PCa ) in
men and
dogs . -
pubmed
As
human castrate - resistant
PCa shares several characteristics with the
canine disease , comparative evaluation of novel therapeutic agents is of considerable value for both
species . -
pubmed
In this study , FX-9 's mediated effects were characterized on two
human (
PC-3 ,
LNCaP ) and two
canine (
CT1258 , 0846 )
PCa cell lines , as well as benign solid tissue cells . -
pubmed
BACKGROUND :
Atherosclerosis is a chronic inflammatory condition that affects different arteries in the
human body and often leads to severe neurological complications , such as
stroke and its sequelae . -
pubmed
Members of the let-7 family of miRNAs are well - known with their
tumor suppressor properties as they are expressed at low levels in several types of
human malignancies . -
pubmed
We found that both let-7b and let-7c were significantly altered in
breast cancer and associated with the clinicopathological findings of
patients . -
pubmed
Effect of disinfectant residuals on
infection risks from
Legionella pneumophila released by biofilms grown under simulated premise plumbing conditions . -
pubmed
pneumophila released from biofilms reported previously were integrated into a Monte Carlo framework to estimate the
infection risk of biofilm - derived
L. - pubmed
Stagnation caused by water use patterns and water - saving devices in the premise plumbing can lead to increased
infection risk by biofilm - derived
L. - pubmed
Traumatic spinal cord injury (
SCI ) results in persistent functional deficits due to the lack of axon regeneration within the
mammalian CNS . -
pubmed
Unlike
mammals , the
sea lamprey ,
Petromyzon marinus , robustly recovers locomotion after complete
spinal cord transection ( TX ) . -
pubmed
Brain
metastasis is a major cause of
death in
breast cancer patients . -
pubmed
All the
patients presented with
ecchymosis and intramuscular
hematoma . -
pubmed
To date ,
silibinin (
SBN ) is a one the most studied hepatoprotective
plant - derived agents for prevention / alleviation of
drug - induced liver injury . -
pubmed
In vivo analysis of hepatoprotective effects of
PLGA /
SBN nanoparticles was carried out on
melanoma tumor - bearing syngeneic
mouse model treated with the antineoplastic drug
dacarbazine (
DTIC ) , which often causes severe
hepatotoxicity including development of
veno - occlusive disease . -
pubmed
PURPOSE : Time course of the recovery of otolithic dis - function caused by
superior vestibular neuritis has been examined in fifteen
patients . -
pubmed
OBJECTIVE : To assess the impact of
fondaparinux on
venous thromboembolism (
VTE ) following elective lumbar spine surgery in high - risk
patients . -
pubmed
Increased
wound drainage was seen in 18.5 % of
patients administered
fondaparinux , compared with 25.5 % of untreated
patients ( P = .15 ) . -
pubmed
CONCLUSIONS :
Patients receiving
fondaparinux had lower rates of symptomatic
DVT and
PE and a favorable complication profile when compared with matched controls . -
pubmed
The retrospective nature of this work limits the safety and efficacy claims that can be made about the use of
fondaparinux to prevent
VTE in elective lumbar spine surgery
patients . -
pubmed
Areca palm yellow leaf ( AYL ) disease caused by the
16SrI group phytoplasma is a serious threat to the development of the
Areca palm industry in China . -
pubmed
To gain insights into the association of progressive accumulation of
GlcCer and the
Parkinson ' s disease phenotypes , we generated dopaminergic ( DA ) neurons from induced pluripotent stem cells ( iPSCs ) derived from a
GD1 patient and a healthy donor control , and measured
GlcCer accumulation by liquid chromatography - mass spectrometry . -
pubmed
These results suggest that synthetic mRNA - based method accelerates the analyses of the pathological mechanisms of
Parkinson ' s disease in
GD1 patients and possibly facilitates drug discovery processes . -
pubmed
Conclusion : Use of ACEI or ARBs prior to hospitalization was not associated with adverse outcomes in COVID-19 and the therapeutic benefits of continuing ACEI or ARB in hospitalized
patients with
COVID-19 was not offset by adverse outcomes . -
pubmed
,
SARS - CoV ) and
MERS , in exhibiting severe flu - like symptoms and acute respiratory distress . -
pubmed
Even at the molecular level , many parallels have been identified between
SARS and COVID-19 so much so that the
COVID-19 virus has been named
SARS - CoV-2 . -
pubmed
Importantly , the identification of similarities in how
SARS - CoV and
SARS - CoV-2 access the host , replicate , and trigger life - threatening pathological conditions have revealed opportunities to repurpose drugs that were proven to be effective against
SARS . -
pubmed
Parenteral administration of
gold thioglucose to
mice produces an area or
necrosis in the ventromedial portion of the hypothalamus . -
pubmed
Neisseria catarrhalis empyema in an immunodeficient host . -
pubmed
Meningococcus strains -- standard and those isolated from the cerebrospinal fluid of
patients suffering from the
cerebrospinal meningitis were grown on fluid and solid protein - free nutrient media . -
pubmed
[ Use of
lignocaine phonophoresis and electrophoresis in the treatment of
patients with
ankylosing spondylitis ] . -
pubmed
Experiments with several
patients suffering from
stress incontinence have shown that indirect stimulation of the levator ani with a vaginal stimulator and especially of the anal sphincter with an anal stimulator affects the urethral sphincter in the same way as direct stimulation . -
pubmed
The importance of nursing / social work liaisons in coordinating treatment and follow - up of
head and neck cancer patients is discussed . -
pubmed
Phage susceptibility , enterotoxigenicity and antibiograms of
Staphylococcus aureus strains isolated from
human wounds and
diarrhoea . -
pubmed
The phage types , enterotoxigenicity and antibiograms of
Staphylococcus aureus strains isolated from
human diarrhoea and
skin wounds in Nigeria were determined . -
pubmed
Phage 119 , a
bovine phage , lysed all 19
strains of diarrhoeal origin sensitive to group M phages but all
wound strains were resistant . -
pubmed
aureus
strains of
bovine origin associated with
human diarrhoea in Nigeria . -
pubmed
Ultrastructure of
hepatocellular neoplasms in
aflatoxin B1 (
AFB1)-initiated
rainbow trout (
Oncorhynchus mykiss ) . -
pubmed
The fine structure of
hepatocellular neoplasms from
aflatoxin B1 (
AFB1)-initiated
rainbow trout was studied by transmission electron microscopy . -
pubmed
Of the 19
patients with
mammary Paget ' s disease , specimens of underlying breast tissue were available from 14 ; all contained a concurrent ductal
adenocarcinoma . -
pubmed
Of the 13
patients with
vulvar Paget ' s disease , 2 had superficial stromal invasion , and 3 had underlying , deeply invasive
adenocarcinomas . -
pubmed
Hepatocellular carcinoma mainly affects
patients with
cirrhosis or with various degrees of
fibrosis . -
pubmed
From 1979 to 1990 , among 87
patients who underwent hepatic resection for
non fibrolamellar hepatocellular carcinoma , 12 ( 14 % ) had a
non fibrolamellar hepatocellular carcinoma developed in a normal liver . -
pubmed
In 7
patients ( 58 % )
hepatocellular carcinoma was associated with clinical manifestations . -
pubmed
Intra or extrahepatic
recurrence was recognized in 8 ( 67 % ) , 2
patients were alive respectively 28 and 16 months after treatment of their intrahepatic
recurrence ( resection in one and intraarterial embolisation in one ) . -
pubmed
Ninety - four
patients admitted to a Coronary Care Unit ( CCU ) complaining of
chest pain with the preliminary diagnosis suspect
MI were included in the study . -
pubmed
The results correlate well with the
carcinogenic activity of these oils in experimental animals , helping to substantiate the conclusion that petrol engine oils ( but not diesel engine oils ) may present a carcinogenic risk to
man if appropriate measures to minimise skin contact are not observed . -
pubmed
35
tumors of brain , spinal cord and cranial and peripheral nerves were induced with
ENU (
ethyl - nitrosourea ) in the offspring of treated BD - IX pregnant
rats . -
pubmed
36
tumors--35 of the nervous system , one
nephroblastoma -- were observed in 14
rats . -
pubmed
With these results , the number of experimental nervous system
tumors of the own collection induced in BD - IX
rats and classified next to the rules of
human neurooncology , amounts to 2,216 . -
pubmed
Recovery of contractility and pHi during
respiratory acidosis in
ferret hearts : role of Na
(+)-H+ exchange . -
pubmed
[ Treatment of
anemia with
animal blood preparation " Livex " in
children with
pyelonephritis ] . -
pubmed
The results are presented of
anaemia treatment during
pyelonephritis in 20
children with the preparation obtained from
animal blood livex . -
pubmed
In
acute toxicity tests with BALB / c
mice no
deaths were recorded even at a dose level of 2 g / kg body wt / day . -
pubmed
To our knowledge , this is the first documented case of isolated
pulmonary phaeohyphomycosis due to
E dermatitidis , and it was successfully treated with
amphotericin B and
5 - fluocytosine . -
pubmed
The
propofol patients were significantly better relaxed and had a higher incidence of
hypotension during the procedure . -
pubmed
The
methohexitone patients had higher
pulse rates and a higher frequency of
hiccups during the procedure . -
pubmed
Morphohistometric investigations of placentas of
diabetic patients in correlation to the metabolic adjustment of the disease . -
pubmed
In addition , the potential
irritative action of the same preparation of IDU was investigated in a more suitable
animal model . -
pubmed
Experiments on
guinea pigs showed slight transient
erythematous responses in three
animals of the test group following first challenge , and in one
animal of the test group and one of the control group , following the second challenge . -
pubmed
The surgical operations including 5 cholecystectomies , gastrectomy , and graft implantation for
abdominal aortic aneurysm were performed on 7
patients 2 to 98 months after valve replacement . -
pubmed
There were two episodes of
hemorrhage required blood transfusion , observed in
patients receiving
heparin therapy , but there was no
thromboembolism . -
pubmed
Use of this technique has allowed us to ascertain that isolated
rib lesions in two
patients with
extra - osseous malignancies were not due to
metastatic disease . -
pubmed
Both lpr / lpr and gld / gld
mice and an
AILD patient with
lymphadenopathy and high myb RNA in peripheral blood cells were treated with
cyclophosphamide (
CY ) . -
pubmed
A single large dose of
CY led to marked regression of the
lymphadenopathy of gld / gld
mice and long - term amelioration of their
autoimmune syndrome . -
pubmed
In contrast , similar treatment of
lpr / lpr mice failed to alter either the
lymphadenopathy or the disease process . -
pubmed
The
AILD patient reacted much like the gld / gld
mice in that myb RNA levels in the peripheral blood , and bone marrow returned to normal after only three doses of
CY . -
pubmed
The
lymphadenopathy and high levels of LN myb mRNA of the lpr / lpr
mice could be normalized ; this occurred only after long - term treatment with
CY . -
pubmed
Zinc and
wound healing in normal and
chronically ill rats . -
pubmed
Exclusion ,
superinfection immunity and abortive recombinants in I+ X I+
bacterial crosses . -
pubmed
Uterine pouch of the
rabbit as an incubator for
human tumor . -
pubmed
Diuretic responses to water - load in four
strains of
mice . -
pubmed
The kinetics of excretion of water ,
sodium and
potassium following a stomach load of water , with and without an initial injection of
vasopressin , are described in each of four
strains of
mice : RAP , CBA / FaCam , Peru and A / Cam.2 . -
pubmed
The
strains of
mice differed significantly in diuretic lag , maximum rate of diuresis , and 3 hr excretion of water and electrolytes.5 . -
pubmed
32:276 - 292 , 1979 ) revealed a remarkably high rate of spontaneous deletion in viral DNA during lytic
infection of cultured
murine cells with minute virus of
mice (
MVM ) , an autonomous parvovirus . -
pubmed
[ Diagnosis , prognosis and therapeutic results in
urothelial dysplasia in
patients with
bladder cancer ] . -
pubmed
Herpes zoster in
patients with
systemic lupus erythematosus . -
pubmed
Acute and chronic complications of laser angioplasty :
vascular wall damage and formation of
aneurysms in the
atherosclerotic rabbit . -
pubmed
Acute and chronic vascular responses to laser exposure in
atherosclerotic rabbits were studied . -
pubmed
In 7
rabbits fed an atherogenic diet for 3 to 5 months before the study to induce
aortic atherosclerosis , a flexible
quartz fiber , 400 micron core diameter , attached to an argon ion laser was passed anterogradely or retrogradely to the atherosclerotic ascending aorta . -
pubmed
In 2
rabbits studied acutely , the argon laser produced a vaporized crater within the
atherosclerotic plaque at the endothelial surface ; however , in 1 there was also
vascular damage extending deep into the medial layer . -
pubmed
In addition ,
aortic aneurysm with
muscular wall damage occurred in 2 of the 4
animals studied chronically . -
pubmed
This study suggests caution in the clinical use of intensive phototherapy to
cardiovascular lesions and stresses the need for further understanding of laser vascular consequences before application of laser angioplasty in
patients . -
pubmed
Fatal
Shigella dysentery complicated by
toxic megacolon and
bone marrow aplasia in a
patient with
chronic granulocytic leukemia in remission . -
pubmed
A
patient with Philadelphia positive
chronic granulocytic leukemia in clinical remission is described , who developed
Shigella dysentery complicated by fatal
toxic megacolon ,
pancytopenia and
bone marrow aplasia . -
pubmed
In the present study , the reproducibility of this finding was examined by application of a similar method in seven normal comparison
subjects and seven neuroleptic - naive
schizophrenic patients examined by PET before and after administration of
haloperidol , 7.5 mg . -
pubmed
Long - term follow - up study of " epileptic type "
moyamoya disease in
children . -
pubmed
Twenty - three
patients with
epileptic type moyamoya disease are reviewed among 200
moyamoya disease patients . -
pubmed
Nineteen
patients improved and suffered no
seizure without receiving antiepileptic drugs , but four
patients developed true
epilepsy and three of these suffered
cerebral infarction . -
pubmed
Treatment of
thalassemia major requires consideration of the available therapeutic options for each
patient , and the risk / benefit ratio of a supportive versus curative approach . -
pubmed
The influence of some fermentation parameters on
vitamin B12 formation by
strains of
Citrobacter freundii and
Klebsiella pneumoniae isolated from
Indonesian tempeh samples during
tempeh fermentation was investigated . -
pubmed
This result supports the suggested use of these two
strains to form
vitamin B12 during
tempeh fermentation in Indonesia . -
pubmed
Quinolones in treatment of
human brucellosis : comparative trial of
ofloxacin -
rifampin versus
doxycycline -
rifampin . -
pubmed
Gastric discomfort was the major side effect observed in 13
patients ( 43.3 % ) who received
doxycycline plus
rifampin , whereas only 2 patients ( 6.5 % ) treated with
ofloxacin plus
rifampin complained of
gastric irritation . -
pubmed
Absence epilepsies , which are easily recognized by the provocation of an episode during
hyperventilation and by the typical features of the EEG , can be overdiagnosed , especially in the
child who daydreams in class and has scattered , asymptomatic , epileptogenic EEG changes . -
pubmed
As in adults , complex partial
seizures in
children can be difficult to distinguish from certain behaviors . -
pubmed
Some recurrent nonepileptic events seen in
children can be mistaken for
seizures , including
shuddering attacks ,
paroxysmal vertigo , breath - holding spells ,
cardiogenic syncope ,
night terrors , and
movement disorders , such as
paroxysmal kinesigenic choreoathetosis . -
pubmed
[ Characteristics of left ventricular systolic and diastolic functions in
patients with essential
hypertension ] . -
pubmed
The aim of this study was to assess the degree of residents ' concern about acquiring
hepatitis B virus (
HBV ) and
human immunodeficiency virus ( HIV ) infection from their patients at the University College Hospital , Ibadan , Nigeria . -
pubmed
In general , the results demonstrate a major degree of concern about acquiring
HBV and
HIV infections among resident doctors . -
pubmed
Erection failure as a sequela to
obstructive urolithiasis in a male
goat . -
pubmed
Aborted
sudden death as the presenting manifestation of
hypertrophic cardiomyopathy in a 14 - year - old
child is reported . -
pubmed
Left ventricular hypertrophy may develop during childhood in
patients with
hypertrophic cardiomyopathy . -
pubmed
RESULTS : A
polyp was diagnosed in 12
patients , a
submucous myoma in one
patient , a proliferated endometrium in five
patients and a
placental polyp in one
patient . -
pubmed
A sonographic irregular structure was diagnosed in one
patient which turned out to be
coagula on hysteroscopy and histology . -
pubmed
Patients with
multiple system atrophy (
MSA ) often have cold , dusky , violaceous hands , with poor circulatory return after blanching by pressure . -
pubmed
Baseline skin temperature in the MSA group was significantly lower than in both the
PD and control groups , and four of the nine
MSA patients were colder at baseline than the coldest control value . -
pubmed
BACKGROUND AND OBJECTIVE : Antiplatelet agents are often included in plasma exchange - based regimens for
thrombotic thrombocytopenic purpura (
TTP )
patients ; however , the opportuneness of their use in
TTP is still controversial . -
pubmed
METHODS : Seventy - two
TTP patients were randomized to receive plasma exchange and
steroids with ( group B ) or without ( group A )
aspirin and
dipyridamole . -
pubmed
RESULTS : Regarding the treatment of acute phase
TTP , similar overall response rates were observed in the two groups ( 91.4 % in group B vs. 75.6 % in group A ) , but lower mortality rates were observed at 15 days in the
patients treated with antiplatelet agents ; as a matter of fact , 5
patients from arm A died in the first 15 days ( 13.5 % ) versus only one in arm B ( 2.8 % ) . -
pubmed
These figures , while not statistically significant , seem to suggest that antiplatelet agents might be useful in preventing
deaths in acute
TTP ; moreover ,
bleeding did not worsen in antiplatelet agent - treated
patients . -
pubmed
As for the role of maintenance treatment , our results support the efficacy and safety of one - year
ticlopidine therapy since the current
relapse rate is significantly higher in non - treated
patients ; as a matter of fact , 6
patients ( 21.4 % ) in the non -
ticlopidine group and only 2 ( 6.25 % ) in the
ticlopidine group relapsed ( P = .0182 in favor of maintenance treatment ) . -
pubmed
INTERPRETATION AND CONCLUSIONS : Our results suggest the usefulness of antiplatelet agents in the treatment of acute phase
TTP patients . -
pubmed
[ Treatment of
cerebral metastasis in
patients with
testicular germ cell tumors ] . -
pubmed
Coronary angioscopy , intravascular ultrasound , and angiography were compared in 20
patients regarding their sensitivity and specificity in the detection of
thrombus . -
pubmed
PATIENTS AND METHODS : Fifty - seven
patients with 58 cases of
breast cancer were evaluated preoperatively with MRI using a technique called the triple - acquisition rapid gradient echo technique to maximize anatomic detail . -
pubmed
Between January 1995 and January 1998 , 21
patients with
oesophageal compression due to
malignant mediastinal tumours underwent oesophageal stent placement for palliation of
dysphagia . -
pubmed
Of the 17
patients , 16 reported an improvement in
dysphagia . -
pubmed
Early complications ( within 48 h ) in the form of mild to moderate retrosternal
chest pain occurred in 5
patients . -
pubmed
In 2
patients the stent was overgrown by
tumour and in one of these an additional stent was placed . -
pubmed
In 1
patient incomplete closure of a
tracheo - oesophageal fistula was observed . -
pubmed
Dystonia is often associated with
myoclonus ,
rigidity ,
apraxia ,
alien hand phenomenon , and sensory cortical signs in the affected limb , and there are no significant differences between the occurrence of these or other features , between
patients with or without
dystonia . -
pubmed
Magnetic resonance imaging findings in 13
patients with
acute transverse myelitis are reviewed . -
pubmed
Activation of serotonergic pathways from the midbrain raphe system to the subfornical organ by
hemorrhage in the
rat . -
pubmed
Mutans streptococci and
Lactobacillus as risk factors for
dental caries in 12 - year - old children . -
pubmed
Spinal cord blood flow changes following systemic
hypothermia and
spinal cord compression injury : an experimental study in the
rat using Laser - Doppler flowmetry . -
pubmed
METHODS : Twenty - four
rats were randomized either to thoracic laminectomy only ( Th VII - IX ) or to 35 g
spinal cord compression trauma . -
pubmed
The
animals were further randomized to either constant normothermia ( 38 degrees C ) or to a systemic cooling procedure , ie reduction of the esophageal temperature from 38 to 30 degrees C. SCBF was recorded 5 mm caudal to the
injury zone using Laser - Doppler flowmetry which allows a non - invasive continuous recording of local changes in the blood flow . -
pubmed
We show the concrete case of a 66 years
woman , who has a due to
toxic multinodular goiter hyperthyroidism with
jaundice and serious
pulmonary hypertension associated , unexplainable by further causes , both regressing with normalisation of thyroid function with no evidence of associated autoimmune pathology . -
pubmed
The disease of
Epstein - Barr virus (
EBV ) -associated recurrent
necrotic papulovesicles is a distinct clinicopathologic entity different from classic
hydroa vacciniforme (
HV ) . -
pubmed
OBJECTIVE : Subsequent to an outbreak of invasive
Paecilomyces lilacinus mycosis among patients of an isolation ward , probably caused by a contaminated skin care product , the microbiological quality of different skin care products from the market was investigated . -
pubmed
CPA can be the natural ending of a normal and long life ; however , when CPA is the result of a reversible problem in an
animal that has a treatable medical condition , rapid recognition and treatment may make the difference between a happy ending and
premature death . -
pubmed
The term cardiopulmonary cerebral resuscitation originated in the early 1960s in recognition of the severe central nervous system complications of prolonged
cardiac arrest in
human beings . -
pubmed
Although neurologic complications of
CPA may not be as noticeable in companion
animals , newer brain - sparing strategies that recognize the consequences of
reperfusion injury and the inflammatory cascade may some day offer improved survival . -
pubmed
METHODS : Thirteen adult
dogs were randomly assigned to one of two study groups 6 hours after the induction of severe
intra - abdominal infection . -
pubmed
The
wound complication rate was 3.5 % for axillae and 7 % for
patients . -
pubmed
PATIENTS AND METHODS : Eighty - three
patients underwent endoscopic
sinus surgery for refractory chronic
sinusitis . -
pubmed
CONCLUSIONS : Duration of the symptoms of chronic
sinusitis in
children of more than 6 months was not a predictor of success of endoscopic
sinus surgery in these
children . -
pubmed
Seven of 11
patients with
WM had an M - protein & gt;3 g / dl and five
patients had bone surveys performed that were negative for
osteolytic disease . -
pubmed
Cognitive function and fMRI in
patients with
multiple sclerosis : evidence for compensatory cortical activation during an attention task . -
pubmed
Mild
cognitive impairment has frequently been reported for
patients in the early stages of
multiple sclerosis . -
pubmed
Expanded brain activation of
multiple sclerosis patients with normal motor function compared with healthy controls during a finger tapping paradigm has previously been reported . -
pubmed
Compensatory brain activation in
patients with
multiple sclerosis compared with normal controls may also be observed when the
subjects are performing cognitive functions . -
pubmed
All
patients were within 3 years of diagnosis and were not suffering from a
relapse at the time of investigation . -
pubmed
The
multiple sclerosis patients were compared with a control group of 21 healthy
volunteers matched for handedness , age , years of education and sex . -
pubmed
Univariate and multivariate analyses were performed to find any demographic parameters ( ie , sex , age , height , and
body weight ) , clinical characteristics ( ie , nutritional or developmental status , co -
infection with
hepatitis viruses [ B or C ] or
human immunodeficiency virus , presence of
extrapulmonary tuberculosis , or medical history of
liver disease ) , or individual antituberculosis agents used that would be associated with the likelihood of development of severe
hepatotoxicity during antituberculous chemotherapy . -
pubmed
Severe
hepatotoxicity developed in 8 of the 99 eligible
children , and all 8 of those children were younger than 5 years old . -
pubmed
The univariate analysis revealed that the
children in whom
hepatotoxicity developed were significantly ( P & lt;.05 ) younger , were predominantly male , had
extrapulmonary tuberculosis , and were given
pyrazinamide more often than those who had no
hepatotoxicity . -
pubmed
However , the multivariate logistic regression analysis revealed that only age and the administration of
pyrazinamide would have a significant contribution ( P & lt;.05 ) to the development of severe
hepatotoxicity , with odds ratios of 143 ( 95 % confidence interval , 4.2 to 4934.9 ) and 0.60 ( 95 % confidence interval , 0.39 to 0.90 ) , respectively : the estimated probability of development of
hepatotoxicity in a typical pediatric
patient at 1 , 5 , and 10 years receiving
pyrazinamide with
rifampin (
INN ,
rifampicin ) and
isoniazid would be 0.95 , 0.72 , and 0.16 , respectively . -
pubmed
CONCLUSIONS : This study indicated that intensive monitoring of
hepatotoxicity should be performed for younger
children ( & lt;5 years ) receiving
pyrazinamide for antituberculosis chemotherapy . -
pubmed
While this may be appropriate for symptom control in
patients with
tumours that are not hormone responsive ,
patients with
hormone dependent tumours will require safe and effective alternative treatments for menopausal symptoms . -
pubmed
To determine whether maintained
estrogen or
progesterone levels affect
kainic acid ( KA )
seizure patterns or the susceptibility of hippocampal neurons to
death from
seizures , ovariectomized
Sprague - Dawley rats were implanted with
estrogen pellets , 0.1 or 0.5 mg , that generated serum levels of 42.4 + /- 6.6 ( mean + /- SEM ) and 242.4 + /- 32.6 pg / ml or one to six capsules of
progesterone that generated serum levels of 11.00 + /-.72 to 48.62 + /- 9.4 ng / ml . -
pubmed
Progesterone reduced
seizure severity in
animals that received one to four implants ; compared with controls , no difference in
seizure severity was noted for animals with six
progesterone implants . -
pubmed
The reduced
seizures in
progesterone - treated
animals were accompanied by a reduction in the spread of
hippocampal damage ( r(2 ) = 0.87 ; P & lt ; 0.05 ) . -
pubmed
Likewise , in
progesterone - treated
rats , neuron survival and reduction in
seizure scores were correlated ( r(2 ) = 0.76 ; P & lt ; 0.0001 ) . -
pubmed
Indeed , in the
estrogen - treated
rats ,
neuronal death was significantly lower than that observed in
progesterone - treated
animals with equally severe
seizures ( P & lt ; 0.05 ) . -
pubmed
Small
hepatocellular carcinomas in
patients with
liver cirrhosis : potentials and limitations of contrast - enhanced power Doppler sonography . -
pubmed
Detection and characterization of
focal liver lesions are critical for
patients with
liver cirrhosis . -
pubmed
However , prospective studies in the assessment of
patients with suspected
hepatocellular carcinoma (
HCC ) in
liver cirrhosis are rare . -
pubmed
RESULTS : Of 42
persons ( 22
males and 20 females ) with
OAG , 13 ( 31.0 % ) had
PEX . -
pubmed
coli causing
hemorrhage and regression of an experimental
mouse tumor . -
pubmed
[ The effect of
vitamin P on the experimental
toxicity of
tetracycline in
guinea pigs ] . -
pubmed
The relationship between basal and maximum acid output in normal subjects and
patients with
duodenal ulcer . -
pubmed
The c1 - t mutants of
bacteriophage lambda can form prophage at 36 degrees C but cause lysis of sensitive bacteria at temperatures above 42 degrees C. Growth of cultures at 42 degrees to 46 degrees C induces prophage replication and lysis in
Escherichia coli K12 ( lambda c1 - t ) ; lysogenic
strains containing wild - type prophage are not induced to lyse at these temperatures . -
pubmed
[ CAUSE OF
DEATH IN TRAUMATIZED
PATIENTS . -
pubmed
Actinobacillus pleuropneumoniae , the etiological agent of
porcine pleuropneumonia , is able to survive on respiratory epithelia , in tonsils , and in the anaerobic environment of encapsulated sequesters . -
pubmed
Pigs challenged with either of the two mutants in an aerosol
infection model showed a lower
lung lesion score than that of the
A. - pubmed
The authors report 9
patients who presented with
loss of consciousness (
syncope ) due to occlusive
carotid artery diseases . -
pubmed
The attack was associated with
dehydration or
hypotension in 5
patients . -
pubmed
Cerebral angiography revealed occlusion of the unilateral internal carotid artery ( ICA ) in 7
patients , severe
stenosis of the bilateral ICA in one , and occlusion of the unilateral ICA and severe
stenosis of the contralateral ICA in one . -
pubmed
No further episode of
syncope occurred in all 9
patients during follow - up periods . -
pubmed
Tyrosinemia resulting from administration of protein - dense infant diets was detected by newborn screening in two
infants . -
pubmed
Loss of normal tight junction functions constitutes a hallmark of
human carcinomas . -
pubmed
PATIENTS AND METHODS : Between January 2002 and January 2004 , 32 male
patients with symptomatic
urethral strictures ( 8 bulbar , 9 penile , 9 combined ) were treated with Ho : YAG - laser urethrotomy in our department . -
pubmed
No
intraoperative complications were encountered , although in 5 % of
patients , a
urinary - tract infection was diagnosed postoperatively . -
pubmed
Spontaneous regression of
optic pathways gliomas in three
patients with
neurofibromatosis type I and critical review of the literature . -
pubmed
CASE REPORTS : The authors report their experience about three
children ( two
girls , one
boy ; average age 1.6 years ) with a spontaneous regression of
optic gliomas . -
pubmed
The knowledge that this kind of
tumor , particularly in young
patients , may regress is important in the decision of the best therapeutic approach . -
pubmed
Proteasome inhibition attenuates
hepatic injury in the bile duct - ligated
mouse . -
pubmed
Our aims were to assess the effect of the proteasome inhibitor
bortezomib on
liver injury in the BDL
mouse . -
pubmed
Liver injury was assessed in 7 - day
BDL mice treated with a single dose of
bortezomib on day 4 after bile duct ligation . -
pubmed
In conclusion , these data suggest that the proteasome inhibitor
bortezomib reduces hepatocyte
injury in the
BDL mouse by mechanisms associated with a reduction in hepatocyte apoptosis , a decrease in Kupffer cell / macrophage number and activation , and increased hepatocyte proliferation . -
pubmed
METHODS : Digital intubation was performed by 18 emergency medicine
residents and 4 staff emergency medicine physicians on 6 different
cadavers . -
pubmed
New techniques to understand chromosome dosage :
mouse models of
aneuploidy . -
pubmed
Mice are the
organism of choice to help us try to tease apart the complex relationships between genotype and phenotype in
aneuploidy and segmental aneusomy
syndromes . -
pubmed
As new technologies such as chromosome engineering and the creation of transchromosomic
mice become routine , these will help us identify individual dosage - sensitive genes that are causative in specific
syndromes and will enable us to produce
mouse models to accurately recapitulate
human chromosomal disorders . -
pubmed
The aim of this study was to identify the molecular
genetic defect and determine its functional consequences in a
patient with
type II Glanzmann thrombasthenia . -
pubmed
Behavioural and psychological symptoms of
dementia (
BPSD ) are a frequent problem in
patients with
dementia . -
pubmed
Three studies suggested possible short - term efficacy , tolerability and safety of
divalproex sodium for
agitation and some other
neuropsychiatric symptoms associated with
dementia in elderly
patients ; in two of these studies , the findings were obtained only on analysis of secondary outcomes . -
pubmed
Further research is needed to determine the optimal use of
divalproex sodium for the treatment of neuropsychiatric symptoms of
dementia and the long - term benefits , if any , of its use in this
patient population . -
pubmed
Sleep disturbances are among the most common symptoms in
patients who have acute episodes of
mood disorders , and patients who have
mood disorders exhibit higher rates of
sleep disturbances than the general population , even during periods of remission . -
pubmed
Recently ,
strains of
Streptococcus bovis were reclassified as
Streptococcus gallolyticus . -
pubmed
Compared to
strains representing previously derived phylogeny , including the
S. - pubmed
equinus complex , the 16S rRNA - derived phylogeny of the
strains investigated in this study demonstrated a paraphyletic group (
S. - pubmed
At three of the four farms most of the pregnant
cows were affected with
alopecia with or without
pruritus in January , and 25 % of the
cows in one herd died during the winter . -
pubmed
The investigation indicated that
CSS was associated with feeding moldy cereal straw to pregnant beef
cows during the winter . -
pubmed
Patients with
grass pollen allergy were randomly allocated to four groups , and received daily a standardized tablet at different doses . -
pubmed
Concurrent chemoradiotherapy for T4
patients with
hypopharyngeal and laryngeal squamous cell carcinomas . -
pubmed
OBJECTIVES : Concurrent chemoradiotherapy ( CCR ) was given for the previously untreated T4
hypopharyngeal and laryngeal squamous cell carcinoma patients and the response and survival rates were evaluated . -
pubmed
RESULTS : Ten out of the 15 hypopharyngeal
carcinoma patients and 4 out of the 8
laryngeal carcinoma patients showed a complete response at the primary sites . -
pubmed
The 5 - year disease - specific survival rate was 59.4 % in all the
patients , 51.9 % in the
hypopharyngeal carcinoma patients , and 71.0 % in the laryngeal
patients . -
pubmed
Seven out of the 12 resectable
hypopharyngeal carcinoma patients and 4 out of 8
laryngeal carcinoma patients were able to do without total laryngectomy . -
pubmed
CONCLUSIONS : Based on these results , the survival rate in the hypopharyngeal and laryngeal T4
carcinoma patients treated by CCR seems to be satisfactory and the possibility of organ preservation for the advanced
patients is indicated . -
pubmed
METHODS : One hundred seventy - eight hospital - based
asthmatic children and 277 community - based controls aged from 5 to 12 years were recruited in southern Taiwan . -
pubmed
Diffuse
axonal damage ,
myelin impairment ,
astrocytosis and inflammatory response following microinjections of
NMDA into the
rat striatum . -
pubmed
METHODS : This is a secondary , qualitative analysis of video - recorded , semi - structured and open - ended interviews with the 130 community - dwelling
patients with mild - to - moderate
AD from the Video - Imaging Synthesis of Treating
Alzheimer ' s Disease ( VISTA ) study - a four - month , randomized , placebo - controlled trial of
galantamine . -
pubmed
Epidemiological observations have shown that oxidative stress is one of the major sources of
carcinogenesis , the top - ranked cause of
human mortality worldwide . -
pubmed
Both
human cancers and
mouse models have confirmed that mutations or altered expression of components of this pathway are associated with
prostate tumors . -
pubmed
[ Influence of
Zea mays L.
saponin ( ZMLS ) on ultrastructure of kidney and pancreas in
diabetes rats induced by
streptozocin ] . -
pubmed
OBJECTIVE : To discuss the effect of
Zea mays L.
saponin ( ZMLS ) on ultrastructure of kidney and pancreas in the
diabetes rats induced by
streptozocin . -
pubmed
METHOD : The
diabetic rat model was established by injections of
STZ , blood
glucose , the ultrastructure of the kidney and pancreas were observed . -
pubmed
We hypothesized that
patients with
anterior temporal abnormalities would exhibit
impaired auditory naming , yet normal range visual naming , whereas
patients with
posterior temporal abnormalities would exhibit impaired performance on both tasks . -
pubmed
Thirty - four
patients with documented
anterior temporal abnormalities and 14
patients with documented
posterior temporal abnormalities received both naming tests . -
pubmed
As hypothesized ,
patients with
anterior temporal abnormalities demonstrated
impaired auditory naming , yet normal range visual naming performance . -
pubmed
Patients with
posterior temporal abnormalities were
impaired in visual naming ; however , auditory naming scores were intact . -
pubmed
Although these group patterns were statistically significant , on an individual basis , auditory - visual naming asymmetries better predicted whether individual
patients had
anterior or posterior temporal abnormalities . -
pubmed
Biomarkers of
lung damage associated with
tobacco smoke in induced sputum . -
pubmed
The purpose of this narrative review is to summarize publications reporting cellular , soluble or volatile marker of
obstructive lung disease in populations of healthy non - smokers and healthy smokers , in order to determine whether the biomarkers examined could be specifically associated with exposure to
tobacco smoke rather than with
inflammation and airway hyper - reactivity . -
pubmed
We describe a
patient who was admitted to our hospital with
deep vein thrombosis at 18 weeks of gestation and who developed
heparin - induced
thrombocytopenia during her antenatal care . -
pubmed
In culture , neonatal
rat ventricular myocytes mature to form striated myocytes and electrically uncoupled skeletal myotubes simulate
fibrosis seen in the healed IBZ . -
pubmed
No adverse effects were reported except for temporary
pruritus immediately after the application of
pimecrolimus 1 % cream in one
patient . -
pubmed
CONCLUSION : Although the interpretation of efficacy was limited by the open - label , non - controlled study design and the small number of
patients , this trial suggests that
pimecrolimus 1 % cream may be a successful treatment choice for
patients with resistant
seborrheic dermatitis of the face . -
pubmed
BACKGROUND : We studied the clinical characteristics and outcomes of
patients undergoing pneumonectomy after preoperative concurrent chemoradiation for
non - small cell lung cancer . -
pubmed
METHODS : Clinical records of
patients with
non - small cell lung cancer who underwent pneumonectomy at our institution between 1995 and 2005 after preoperative concurrent chemoradiation were reviewed retrospectively . -
pubmed
Of the 21
men and 8
women who were treated , 1 had stage IIB ( T3N0M0 ) and the remainder had stage IIIA or IIIB
non - small cell lung cancer . -
pubmed
Recurrences have been found in 11
patients ( 38 % ) , including
brain metastases ( n = 6 ) ,
bone metastases ( n = 4 ) , liver
metastases ( n = 2 ) , and cervical lymph node metastases ( n = 2 ) . -
pubmed
One
patient had a contralateral new primary
lung cancer develop 70 months after undergoing pneumonectomy . -
pubmed
Quality and quantity of diffuse and focal
white matter disease and
cognitive disability of
patients with
multiple sclerosis . -
pubmed
CONCLUSIONS : The use of 3 T MRI in a sample of clinically stable
MS patients shows the importance of
WM disease in hampering processing speed and word retrieval . -
pubmed
The impact of
fatigue should be considered with the aim of improving quality of life and care of
patients with
epilepsy . -
pubmed
Integrated population pharmacokinetics of
etanercept in healthy subjects and in
patients with
rheumatoid arthritis and
ankylosing spondylitis . -
pubmed
Etanercept pharmacokinetics in
patients with
rheumatoid arthritis (
RA ) ,
ankylosing spondylitis (
AS ) , and
psoriasis were assessed separately with distinct models using population pharmacokinetics methods of limited precision . -
pubmed
This integrated analysis aimed to establish a framework to evaluate previously established population pharmacokinetic models of
etanercept , and to identify consistent and important demographic and disease factors that affected etanercept pharmacokinetics in a diverse population of healthy subjects and
patients with
RA and
AS . -
pubmed
In this integrated analysis , cumulative rich and sparse
etanercept concentration data from 53 healthy
volunteers , 212
patients with
RA , and 346
patients with
AS were examined and compared using nonlinear mixed effect methodology implemented the in NONMEM VI software package . -
pubmed
In adult
patients with
RA and
AS , age and
body weight do not significantly affect
etanercept pharmacokinetics . -
pubmed
HPV - immune response to
infection and vaccination . -
pubmed
Failure to develop effective CMI to clear or control
infection results in persistent
infection and , in the case of the oncogenic
HPVs , an increased probability of progression to
CIN3 and invasive
carcinoma . -
pubmed
The prolonged duration of
infection associated with
HPV seems to be associated with effective evasion of innate immunity thus delaying the activation of adaptive immunity . -
pubmed
Assessing subtle structural changes in
Alzheimer ' s disease patients . -
pubmed
Lactococcus lactis as an adjuvant and delivery vehicle of antigens against
pneumococcal respiratory infections . -
pubmed
The progress made so far in the protective immune response induced by recombinant vaccines , the successful trials in animal models and the safety considerations of their application in
humans suggest that the use of recombinant vaccines represents a good short - term option in the control of
pneumococcal diseases . -
pubmed
Five miRNAs of
Epstein - Barr virus (
EBV ) were also detected in
EBV - infected nasopharyngeal carcinoma cells , while they did not appear in non - virus infected cells . -
pubmed
METHODS : We recruited 46
patients ( 27
men , 19
women ; median age 70 years ) with clinical
stage I lung adenocarcinoma who had undergone pulmonary resection with mediastinal lymph node dissection . -
pubmed
This article is devoted to assessing the adequacy and safety of total intravenous anesthesia based on constant dosed infusion of
propofol and high thoracic epidural analgesia in thoracic surgical procedures requiring an artificial one - lung ventilation in
patients with concomitant chronic
cardiorespiratory disorders compared to TIVA without a high thoracic epidural analgesia . -
pubmed
Delayed endovascular revascularization in a
patient with progressive
neurological deterioration from bilateral
intracranial vertebral artery occlusions : case report . -
pubmed
BACKGROUND AND IMPORTANCE : This article describes delayed endovascular revascularization in a
patient with clinical and radiographic evidence of
posterior circulation hemodynamic failure in the setting of
intracranial occlusive lesions . -
pubmed
CLINICAL PRESENTATION : A 48 - year - old
man presented with a 6 - week history of progressive
headache ,
nausea , and
ataxia . -
pubmed
Bilateral
intracranial vertebral artery occlusions and a left
posterior inferior cerebellar artery stroke were diagnosed , and the
patient began
warfarin therapy . -
pubmed
Despite these measures , the
patient developed dense lower
cranial neuropathies , including severe
dysarthria , decreased left - sided hearing acuity , and left facial droop . -
pubmed
The
patient underwent successful revascularization with intravascular Wingspan stents ( Boston Scientific , Natick , Massachusetts ) in a delayed fashion ( approximately 6 weeks after his initial
stroke presentation ) . -
pubmed
CONCLUSION :
Patients with
arterial occlusion should be evaluated acutely for potential revascularization . -
pubmed
A subpopulation of
patients will present with progressive deficits distinct from extracranial manifestations of
vertebrobasilar insufficiency ; these
patients should be considered for delayed revascularization . -
pubmed
Selective changes of retroelement expression in
human prostate cancer . -
pubmed
Whether this re - expression really occurs in
human cancers is largely unkown . -
pubmed
In particular , LINE-1 hypomethylation does not lead to generalized overexpression , but specific
human endogenous retrovirus - K proviruses display conspicuous changes in their expression hinting at significant functions during prostate
carcinogenesis . -
pubmed
Vibrio parahaemolyticus isolates from southeastern Chinese coast are genetically diverse with circulation of clonal complex 3
strains since 2002 . -
pubmed
parahaemolyticus
strains and 73.3%-76.9 % identity to the CDS24 of a
Vibrio sp . - pubmed
PARTICIPANTS :
Volunteers ( N=25 ) without
low - back pain . -
pubmed
These include surveillance of foodborne pathogens , microbial source tracking , risk assessment , and
human populations at increased risk of
infection by foodborne microbes . -
pubmed
Vitamin D deficiency is associated with poor outcomes and increased mortality in severely ill
patients . -
pubmed
In this study , we assessed the correlation between circulating
vitamin D levels and mortality rates in
critically ill patients . -
pubmed
Among the deceased
patients , survival curves indicated that survival of
patients with
vitamin D deficiency was significantly shorter than those whose
vitamin D concentration was & gt;20 ng / ml ( P & lt ; 0.05 ) ; the average survival time was 15.3 + - 12.4 days for
vitamin D deficient
patients compared with 24.2 + - 16.5 days among those with normal
vitamin D levels . -
pubmed
We recommend assessing the effects of
vitamin D supplementation in
critically ill patients . -
pubmed
The symptom that improved most was
photophobia ( improved in 19
patients , 82.6 % ) . -
pubmed
By interrogating public databases , we have found that over - expression of this signature correlates with poor relapse - free survival in
breast cancer patients . -
pubmed
Ninety - nine liver
metastases ( 72
patients ) , 48
hepatocellular carcinomas ( 42
patients ) , and six
cholangiocarcinomas were treated . -
pubmed
PATIENTS : A total of 28,581
patients , aged 18 to 65 years , who underwent craniotomy for a
brain tumor . -
pubmed
Patients with relapsed stage 4
neuroblastoma have an extremely poor long - term prognosis , making the investigation of new agents of interest . -
pubmed
After 3 cycles of
decitabine and vaccine , this
patient achieved a complete remission and is now 1 year from his last treatment , with no evidence of
tumor in his bone marrow or other sites . -
pubmed
RESULTS : Of 385 eligible
patients , six were excluded because of pre - existing
hydronephrosis or suspected
intra - operative ureteral injury . -
pubmed
CONCLUSION : Mild
hydronephrosis is a frequent finding after uncomplicated hysterectomy for benign pathology in otherwise asymptomatic
patients . -
pubmed
BACKGROUND : The
Asian corn borer ( ACB ) ,
Ostrinia furnacalis ( Guenee ) , has become the most damaging pest in
corn in south - east Asia . -
pubmed
Bacillus thuringiensis (
Bt ) and
Bt herbicide - tolerant ( BtHT )
corns have been developed to reduce borer attacks worldwide . -
pubmed
PATIENTS : 75 consecutive revision TKA in 75
patients were included and stratified according to a
BMI greater or smaller than 30 kg / m2 and a
body weight greater or smaller than 90 kg . -
pubmed
Noroviruses ( NoVs ) are important
human pathogens associated with foodborne and
waterborne gastroenteritis . -
pubmed
However , the vast majority of
human infections are associated with variants of a unique genotype , GII.4 . -
pubmed
The presence of
GIV NoV both in sewage and in clinical samples confirms that not only GI and
GII NoVs but also
GIV strains are circulating in
humans . -
pubmed
Data on the efficacy of
ustekinumab in
patients with moderate - to - severe
Crohn ' s disease , especially in
patients previously treated with
infliximab , have been recently published . -
pubmed
BACKGROUND : Many
patients with moderate - to - severe
atopic dermatitis (
AD ) require systemic immunomodulating treatment to achieve adequate disease control . -
pubmed
PURPOSE OF REVIEW : A small proportion of
patients with
asthma have severe disease characterized by persistent
airflow obstruction ,
airway hyperresponsiveness and
eosinophilic airway inflammation . -
pubmed
SUMMARY : In severe refractory
asthma , both an understanding of the underlying pathophysiologic mechanisms driving
airway inflammation and the identification of appropriate biomarkers in individual
patients are critical in guiding the use of biologics and monoclonal antibodies that target the specific
pathological processes . -
pubmed
Proarrhythmic effect of " reverse mode switch " in a
patient with
long - QT syndrome . -
pubmed
The results revealed that
hypothyroid rats tended to eat less food and experienced substantial body
weight gain , whereas the
rats with T4 replacement tended to eat more food while continuing to lose weight . -
pubmed
It accounts for approximately 10 % of pathologically confirmed
dementias but has been demonstrated to be as prevalent as
Alzheimer ' s disease in
patients below the age of 65 . -
pubmed
HRSV (
human respiratory syncytial virus ) is a serious cause of
lower respiratory tract illness in infants and young children . -
pubmed
Erratum : efficacy and tolerability of anticholinergics in korean
children with
overactive bladder : a multicenter retrospective study . -
pubmed
The first steps for understanding the functions of DNA methylation and its regulation in
mammalian development have led us to identify common ( epi)genetic mechanisms involved in the eight
human congenital imprinting disorders . -
pubmed
From 2008 to 2013 , 189 consecutive treatment - naive
CHB patients receiving
TDF ( n = 41 ) or
ETV ( n = 148 ) for severe acute exacerbation were enrolled . -
pubmed
In conclusion ,
TDF and
ETV produce a similar treatment response and clinical outcome in
patients with severe acute exacerbation of
CHB . -
pubmed
Bacteriocinogenic potential of a probiotic
strain Bacillus coagulans [ BDU3 ] from Ngari . -
pubmed
The
strain BDU3 was identified as
Bacillus coagulans by phenotypic and genotypic characterization . -
pubmed
Early dynamic
left intraventricular obstruction is associated with
hypovolemia and high mortality in
septic shock patients . -
pubmed
INTRODUCTION : Based on previously published case reports demonstrating dynamic
left intraventricular obstruction (
IVO ) triggered by
hypovolemia or
catecholamines , this study aimed to establish : ( 1 ) IVO occurrence in
septic shock patients ; ( 2 ) correlation between the intraventricular gradient and volume status and fluid responsiveness ; and ( 3 ) mortality rate . -
pubmed
METHOD : We prospectively analyzed
patients with
septic shock admitted to a general ICU over a 28 - month period who presented Doppler signs of IVO . -
pubmed
RESULTS : During the study period , 218
patients with
septic shock were admitted to our ICU . -
pubmed
A rise & gt;=12 % in
stroke index was found in 87 % of
patients with IVO , with a drop of 47 % in IVO after fluid infusion . -
pubmed
CONCLUSION : Left IVO is a frequent event in
septic shock patients with an important correlation with fluid responsiveness . -
pubmed
Objective means are needed to predict and assess clinical response in
patients treated for
invasive aspergillosis (
IA ) . -
pubmed
Patients with proven or probable
IA were prospectively enrolled , and serial GM and
BDG levels and GM optical density indices ( GMI ) were calculated twice weekly for 6 weeks following initiation of standard - of - care antifungal therapy . -
pubmed
Among 47
patients with
IA , 53.2 % ( 25/47 ) and 65.9 % ( 27/41 ) had clinical response by weeks 6 and 12 , respectively . -
pubmed
These results suggest that changes of biomarkers may be informative to predict and/or assess response to therapy and survival in
patients treated for
IA . -
pubmed
Diabetes was induced by
streptozotocin , and mRNA profiles of isolated glomeruli and sorted podocytes from
diabetic and control
mice were examined 10 weeks later . -
pubmed
Expression of podocyte - specific markers in glomeruli was downregulated in
diabetic mice compared with controls . -
pubmed
However , expression of these markers was not altered in sorted podocytes from
diabetic mice . -
pubmed
Gastroprotective Effects of
PMK - S005 against
Ethanol - Induced Acute
Gastric Damage in
Rats . -
pubmed
BACKGROUND / AIMS : This study aimed to examine the gastroprotective effects of
PMK - S005 , which is a synthetic
S - allyl - Lcysteine (
SAC ; a
sulfur - containing
amino acid ) , against acute
ethanol - induced
gastric damage in
rats . -
pubmed
Better understanding of the impact of age at reduction and surgical approach is important to reduce the risk of
osteonecrosis in
patients with
DDH . -
pubmed
Similarly , the odds of
osteonecrosis after open reduction did not differ between
patients treated after the age of 12 months compared with those treated at or before 12 months ( OR , 1.1 ; 95 % CI , 0.7 - 1.9 ; p = 0.7 ) . -
pubmed
The first
patient in whom the technique was used had a left - sided , 1.4 - cm ,
tuberculum meningioma . -
pubmed
OBJECTIVE : We measured visual scanning behavior , using an eye - tracker , to explore attentional bias in the presence of competing stimuli to assess
apathy in
AD patients . -
pubmed
METHODS : Mild - to - moderate
AD patients ( Standardized Mini - Mental Status Examination , sMMSE > 10 ) were assessed for
apathy ( Neuropsychiatric Inventory [ NPI ]
apathy , Apathy Evaluation Scale [ AES ] ) . -
pubmed
Participants were presented with 16 slides , each containing 4 images of different emotional themes ( 2 neutral , 1 social , 1
dysphoric ) . -
pubmed
RESULTS : Of the 36
AD patients ( 14
females , age = 78.2 + -7.8 , sMMSE = 22.4 + -3.5 ) included , 17 had significant
apathy ( based on NPI
apathy > = 4 ) and 19 did not . -
pubmed
The Legacy of Past Pandemics : Common
Human Mutations That Protect against
Infectious Disease . -
pubmed
Lanolin for the treatment of
nipple pain in breastfeeding
women : a randomized controlled trial . -
pubmed
The purpose of this study was to evaluate the effect of
lanolin on
nipple pain among breastfeeding
women with
damaged nipples . -
pubmed
Breastfeeding
women ( N = 186 ) identified as having
nipple pain / damage were randomized to apply
lanolin ( intervention group ; n = 93 ) or to receive usual postpartum care ( control group ; n = 93 ) . -
pubmed
This study investigated whether
tumor - associated macrophages ( TAMs ) have a role in altering NK cell function and phenotype using in vitro cocultures of
murine NK cells with peritoneal or bone marrow - derived , M2 - polarized macrophages or TAMs isolated from spontaneous
mouse breast tumors . -
pubmed
Patients with
anaplastic carcinoma and
metastatic thyroid renal cell carcinoma were excluded . -
pubmed
In multivariate analysis , including
patient age and presence of
malignancy ,
patient age was the only significant predictor of overall survival ( hazard ratio : 1.09 by year , 95 % confidence interval : 1.03 - 1.14 , p=0.00 ) . -
pubmed
BACKGROUND : Host - specific environmental factors induce changes in
Bacillus anthracis gene transcription during
infection . -
pubmed
Introduction : In
patients with mechanical prosthetic heart valves or
atrial fibrillation requiring anticoagulation to prevent
thromboembolic events , several factors influence adherence and anticoagulation complications . -
pubmed
MATERIAL AND SURGICAL TECHNIQUE : Our first case of
PPOM was performed on a 54 - year - old
woman who developed a complex
incisional hernia after multiple abdominal operations . -
pubmed
Extracorporeal life support is safe in
trauma patients . -
pubmed
INTRODUCTION : The role of extracorporeal life support ( ECLS ) in the
critically ill trauma patient is poorly defined , possibly leading to the underutilization of this lifesaving therapy in this population . -
pubmed
This study examined survival rates and risk factors for
death in
trauma patients who received ECLS . -
pubmed
METHODS : Data from the National Trauma Data Bank was retrospectively reviewed to identify
trauma patients who received ECLS from January 2012 to December 2014 . -
pubmed
Analysis of specific anatomic locations of
traumatic injury , including serious head / neck , thoracic , and
abdominal injuries , revealed no impact on
patient survival . -
pubmed
CONCLUSIONS : Extracorporeal life support appears to be an effective treatment option in
trauma patients with severe
cardiopulmonary failure . -
pubmed
Survival in
trauma patients receiving ECLS is similar to that observed in the general ECLS population and this may represent an underutilized therapy in this population . -
pubmed
MATERIALS AND METHODS : A total of 15 observers measured the temporal and nasal Van Herick scores from 18
patients , grouped into cohorts at outpatient
glaucoma and corneal clinic . -
pubmed
Moreover , many retrocopies of protein - coding genes are linked to
human diseases , especially various types of
cancer . -
pubmed
STUDY DESIGN : In the study , 26 premolars were transplanted in 20
patients after traumatic
tooth loss ( n = 16 ) or
congenital aplasia ( n = 10 ) in the anterior maxilla . -
pubmed
CONCLUSIONS : Here we showed that 24 h after experimental
MI in
rats in vivo , apoptosis was induced in the posterior non - in farcted LV wall . -
pubmed
MATERIALS AND METHODS : We retrospectively reviewed the records of
patients who underwent radical cystectomy for
bladder cancer at our institution . -
pubmed
Patients who experienced any
fistula were identified . -
pubmed
RESULTS : Of the 1,041
patients 31 ( 3.0 % ) experienced
fistula formation . -
pubmed
RATIONALE :
Depressed patients robustly exhibit affective biases in emotional processing which are altered by SSRIs and predict clinical outcome . -
pubmed
OBJECTIVES : The objective of this study is to investigate whether
psilocybin , recently shown to rapidly improve mood in treatment - resistant
depression (
TRD ) , alters
patients ' emotional processing biases . -
pubmed
In
patients , this change was significantly correlated with a reduction in
anhedonia over the same time period ( r = .640 , p = .010 ) . -
pubmed
Patients : One hundred four newly diagnosed
T2DM (
nT2DM ) , 109
impaired glucose tolerance (
IGT ) , and 128 healthy
individuals were recruited for this study . -
pubmed
Importance : Locoregional failure for
patients with locally advanced
bladder cancer ( LABC ) after radical cystectomy ( RC ) is common even with chemotherapy and is associated with high morbidity and mortality . -
pubmed
Patients with
bladder cancer 70 years or younger having 1 or more risk factors ( & gt;=pT3b , grade 3 , or positive nodes ) with negative margins after radical cystectomy plus pelvic lymph node dissection were eligible . -
pubmed
Oral examination of 254
school children aged 6 - 18 years revealed an overall dental
caries prevalence of 79.5 % . -
pubmed
Neuroprotective Effects of
Cyclosporine in a
Porcine Pre - Clinical Trial of Focal
Traumatic Brain Injury . -
pubmed
The aim of the present study was to evaluate the efficacy of a novel and
cremophor /
kolliphor EL - free lipid emulsion formulation of
cyclosporine in a translational large
animal model of
TBI . -
pubmed
A mild - to - moderate focal
contusion injury was induced in
piglets using a controlled cortical impact device . -
pubmed
In this study , we have demonstrated efficacy using a novel
cyclosporine formulation in clinically relevant and translatable outcome metrics in a large
animal model of
focal TBI . -
pubmed
CONCLUSIONS / IMPLICATIONS FOR PRACTICE : The results of this study indicate that the dialogue sessions using Steno Balance Cards are beneficial for
patients with
T2DM in terms of improved glycemic control and quality of life . -
pubmed
The authors thus evaluated the relationship between timing of resumption of beta blockers and
atrial fibrillation in
patients recovering from noncardiothoracic and nonvascular surgery . -
pubmed
After propensity score matching on baseline and intraoperative variables , 1,924
patients who did resume beta blockers by the end of postoperative day 1 were compared with 973
patients who had not resumed by that time on postoperative
atrial fibrillation using logistic regression . -
pubmed
RESULTS : Of propensity score - matched
patients who resumed beta blockers by end of postoperative day 1 , 4.9 % ( 94 of 1,924 ) developed
atrial fibrillation , compared with 7.0 % ( 68 of 973 ) of those who resumed thereafter ( adjusted odds ratio , 0.69 ; 95 % CI , 0.50 - 0.95 ; P = 0.026 ) . -
pubmed
Patients who resumed beta blockers on day of surgery had an
atrial fibrillation incidence of 4.9 % versus 5.8 % for those who started thereafter ( odds ratio , 0.84 ; 95 % CI , 0.67 - 1.04 ; P = 0.104 ) . -
pubmed
Effect of
dimethyl fumarate on
neuroinflammation and apoptosis in
pentylenetetrazol kindling model in
rats . -
pubmed
RESULTS : The results showed reduction in the
seizure score , percentage of kindled
rats and
neurological damage score in
DMF treated
rats . -
pubmed
(
hairy nightshade ) plants with numerous
leaf lesions and moderate defoliation were seen . -
pubmed
Radial growth responses of these
strains on
rye grain agar amended with 1 , 10 , or 100 mug per ml of
metalaxyl (
Ridomil 2E ) yielded 50 % effective dose values greater than 100 mug per ml , since percentage growth at the highest fungicide concentration exceeded 50 % of the no
metalaxyl control . -
pubmed
These resistance levels are typical of the
metalaxyl - insensitive
strains of
P. - pubmed
To our knowledge , this is the first report of
infection of
S. - pubmed
Improved treatment outcome of
pembrolizumab in
patients with
nonsmall cell lung cancer and
chronic obstructive pulmonary disease . -
pubmed
This study aimed to investigate the clinical impact of
COPD on the treatment response to ICIs in a large number of
patients with
NSCLC . -
pubmed
In total , 133
patients with spirometry test results were retrospectively identified among those who received palliative pembrolizumab for
NSCLC . -
pubmed
Spirometry - based
COPD was present in 59 ( 44 % )
patients . -
pubmed
Patients with
COPD had better OS ( hazard ratio [ HR ] for
death , 0.45 ; 95 % confidence interval [ CI ] , 0.26 - 0.78 ) and PFS ( HR for
disease progression or
death , 0.50 ; 95 % CI , 0.31 - 0.79 ) than those without
COPD . -
pubmed
Spirometry - defined
COPD was associated with a significantly longer OS and PFS in
patients with
NSCLC treated with palliative
pembrolizumab . -
pubmed
Identifying coexisting
COPD could predict favorable treatment outcomes in
patients with
NSCLC treated with pembrolizumab . -
pubmed
A metagenomic study of
patients with
alveolar osteitis after tooth extraction . -
pubmed
Microbiological samples were taken from the sockets of 10
patients with
dry socket after tooth extraction ( AO group ) and 10 patients in whom
exodontia resulted in no
postoperative complications ( control group ) . -
pubmed
Prevotella nanceiensis ,
Actinomyces odontolyticus ,
Treponema maltophilum ,
Veillonella dispar ,
Tannerella forsythia , and
Leuconostoc mesenteroides were found in several patients with
alveolar osteitis , with an abundance greater than 0.5 % , and were absent in all the control group samples . -
pubmed
Correlations of somatic traits and
postural defects in
girls and
boys aged 10 - 12 . -
pubmed
BACKGROUND : The aim of the study was to analyse correlations between somatic features and variables of
postural defects in
girls and
boys aged 10 - 12 . -
pubmed
AIMS : Ligation of the urethra to create partial
bladder outlet obstruction has widely been used as an
animal model of
bladder obstruction , although obstructive
bladder dysfunction may be due to both mechanical and functional obstruction . -
pubmed
Previous studies in
rodents have demonstrated that long - term
nitric oxide (
NO ) deficiency can lead to
detrusor overactivity , and lack of
NO may thus cause impairment of bladder outlet relaxation . -
pubmed
SIGNIFICANCE : These findings suggest that chronic administration of
L - NAME to
rats induces
bladder hyperactivity with residual urine , and may provide a useful model of functional
bladder obstruction . -
pubmed
Moreover , the original studies employed different clinical assessments and included
manic patients taking other drugs , which made it impossible to determine whether the resolution of symptoms was due to
valproate therapy alone . -
pubmed
Osteonecrosis of the femoral head is the most common complication with identified risk factors including
fracture type ,
patient 's age , degree of displacement , timing to reduction , and stability of fixation . -
pubmed
BACKGROUND :
Tobacco use ,
alcohol use , and
sugar - sweetened beverage consumption are each associated with increased
cancer - risk . -
pubmed
The primary aim of this study is to evaluate the effect of
trauma - informed yoga , drumming , and psychoeducation compared to control on
tobacco use ,
alcohol use , and
sugar - sweetened beverage consumption among community - based adults . -
pubmed
Tai Chi exercise and functional electrical stimulation of lower limb muscles for rehabilitation in older
adults with chronic
systolic heart failure : a non - randomized clinical trial . -
pubmed
Exercise - based training decreases hospitalizations in
heart failure patients but such patients have
exercise intolerance . -
pubmed
A total of 1,084 older
adults with chronic
systolic heart failure were included in a non - randomized clinical trial ( n=271 per group ) . -
pubmed
Accumulating evidence from animal and
human studies supports the notion that physical exercise can enhance neuroplasticity and thus reduce the risk of several
neurodegenerative diseases ( e.g. -
pubmed
We sought to quantify the multiaxial mechanical properties of
murine dissecting
aneurysm samples by combining in vitro extension - distension data with full - field multimodality measurements of wall
strain and thickness to inform an inverse material characterization using the virtual fields method . -
pubmed
Preliminary safety and imaging efficacy of the near - infrared fluorescent contrast agent
DA364 during fluorescence - guided surgery in
dogs with spontaneous
superficial tumors . -
pubmed
Preliminary safety and imaging efficacy of the near - infrared fluorescent probe
DA364 were evaluated during surgical resection of spontaneous solid
tumors in 24
dogs . -
pubmed
Impact of
chronic kidney disease on long - term outcome of
patients with
valvular heart defects . -
pubmed
Coexistence of
chronic kidney disease (
CKD ) in
patients with
VHD increases the risk of
death and affects further therapeutic strategy . -
pubmed
MATERIAL AND METHODS : The inclusion criteria were met by 1025
patients with moderate and severe
VHD . -
pubmed
CKD occurred in 37.1 % ( N = 380 )
patients mostly with
mitral stenosis ( 50 % , N = 16 ) and those with severe
MVI ( 44.8 % , N = 94 ) . -
pubmed
Regardless of the stage ,
chronic kidney disease is an additional factor affecting the prognosis in
patients with
heart defects . -
pubmed
The monitoring of renal function in
patients with
VHD should be crucial as well as the implementation of treatment at an early stage . -
pubmed
Here , we discuss a case of
acute liver failure (
ALF ) with severe
lactic acidosis in a 75 - year - old
female with
diffuse large B - cell lymphoma (
DLBCL ) . -
pubmed
The
patient was admitted with
nausea ,
fevers , and mild
acidosis . -
pubmed
Although radiographic imaging did not demonstrate any
liver abnormality , the
patient soon developed signs of
ALF along with severe
lactic acidosis . -
pubmed
This case highlights an uncommon manifestation of
DLBCL and suggests that an accelerated timeline for beginning chemotherapy may be warranted in
patients with high clinical suspicion of secondary
hepatic lymphoma . -
pubmed
The difference in detection rates of
thrombophlebitis by physician and routine observation along with the demographic and clinical variables contributing to
thrombophlebitis in hospitalized
children were studied . -
pubmed
Obstetric anal sphincter injuries (
OASIS ) in multiparous
women with the use of epidural anaesthesia : A retrospective cohort study . -
pubmed
RESULTS : There were 14 124 multiparous
women who met the inclusion criteria ;
spontaneous labour is associated with an increased risk of OASIS at adjusted odds ratio ( aOR ) 1.46 , P = 0.012 . -
pubmed
Women with epidural use had significantly lower chances of sustaining
OASIS in normal vaginal births and instrumental vaginal births . -
pubmed
CONCLUSION : The use of epidural analgesia in multiparous
women is associated with a reduction in
anal sphincter injuries . -
pubmed
Moreover , in this setting , the observation of the late - onset
toxicity endpoint could be precluded by trial discontinuation due to
death , progression ,
patient withdrawal , or physician discretion , defining a competing event to toxicity . -
pubmed
A non - invasive tool for early detection of
acute leukemia in
children using a paper - based optoelectronic nose based on an array of metallic nanoparticles . -
pubmed
Macrophage and neutrophil responses ,
bacterial dissemination , and
liver damage were assessed following i.v . -
pubmed
infection with a pathogenic
strain of
S. - pubmed
The 5
patients were 41 , 51 , 54 , 76 , and 76 years of age when initial symptoms of
pelvic mass or
pain appeared . -
pubmed
Due to its low incidence , both multicenter clinical studies and molecular studies are required to provide gynecologists with a better understanding and guidance for future management of
patients with
ovarian fibrosarcoma . -
pubmed
Human and
monkey eye globes with
retinal detachment served as controls . -
pubmed
METHODS : Retrospective longitudinal study of
patients with
retinal pigment epithelium ( RPE ) tears secondary to age - related
macular degeneration (
AMD ) . -
pubmed
RESULTS : This study included 32 eyes from 31
patients ( 19 female and 12 male ) , with
RPE tears secondary to
AMD . -
pubmed
( 1977 ) , transhepatic injection of
oesophageal varices has been performed under local anaesthesia in 9
patients with
portal hypertension ( 11 procedures ) . -
pubmed
Bleeding resumed within 2 days of radiologically satisfactory occlusion in 2
patients and at 1 , 3 , 4 and 10 months after 4 procedures in 3
patients . -
pubmed
There were 2 hospital
deaths , both in alcoholic
patients with poor hepatic function . -
pubmed
In spite of the apparently high morbidity we consider that there is a place for this technique in tiding over
patients who are
bleeding from
oesophageal varices and are medically unsuitable for any surgical procedure . -
pubmed
A model of
salmonella enteritis : the behaviour of
Salmonella enteritidis in chick intestine studies by light and electron microscopy . -
pubmed
Separate and combined effect of D
hypovitaminosis and poor protein diet on the parameters of lipid metabolism in the blood serum and liver was investigated experimentally in
albino rats . -
pubmed
The lipid changes in the liver of the test
animals in simultaneous
deficiency of protein and
vitamin D were similar to those in
protein deficiency . -
pubmed
[ Medical rehabilitation of
patients with
central nervous system injuries ] . -
pubmed
[
Acute renal failure in
children ] . -
pubmed
Persistent
vaginal cornification in
mice treated with
estrogen prenatally . -
pubmed
Susceptibility of south Indian
strains of
Mycobacterium tuberculosis to
tuberactinomycin . -
pubmed
A total of 114
strains of
Mycobacterium tuberculosis isolated from sputum samples of 114 patients of
pulmonary tuberculosis in south India , were coded and tested for their in vitro susceptibility to
tuberactinomycin (
Tum ) incorporated in Lowenstein - Jensen ( LJ ) medium . -
pubmed
Western - immunoblotting gave indirect evidence for
infection with
Taenia crassiceps , a
dog 's tapeworm . -
pubmed
Increased bronchial reactivity to cholinergic stimulation is well recognized in
patients with
bronchial asthma . -
pubmed
The case of a young
patient who presented with severe
hemolysis after mitral valve repair is presented . -
pubmed
We studied verbal and visual short term memory , learning capabilities and long term retention in a sample of 96
patients with
Parkinson ' s Disease (
PD ) and 42 controls matched by sex , age , years of education and verbal intelligence . -
pubmed
Forty - one per cent of
patients had
impairment in visual short term memory , and this impairment is related with
bradykinesia and correlated with age of onset . -
pubmed
Twenty - seven
patients with
elbow joint dislocation were reviewed and treated between 1979 and 1983 . -
pubmed
57
patients with
duodenum ulcer were examined . -
pubmed
In conclusion , the isolated glomerulus model allows us to demonstrate the direct vasoconstrictive effect of
CsA , that can in part explain the renal functional changes and the
acute renal failure often described in
human clinic . -
pubmed
A 3 - year - old child experienced
edema of the face and extremities approximately 2 weeks after being stung on the legs , scrotum , and penis by " fire ants " (
Solenopsis invicta ) . -
pubmed
The Authors stress the frequency of
human hydatidosis , still high in Italy , and the severity of the above mentioned complication . -
pubmed
A 20 - year - old
man suffered a closed
head injury followed by symptoms of right - sided labyrinthine
concussion with complete clinical recovery within 3 weeks . -
pubmed
A
patient with a rare
dermatosis ,
actinic reticuloid , is described . -
pubmed
Vomiting occurred in 1
patient in whom the MMC was recorded only on the third postoperative day . -
pubmed
After completion of AM kindling and the repetitive induction of kindled
convulsion , the percentage of time spent in rapid eye movement sleep ( REMS ) significantly decreased , although the
animals began to spend significantly more time in sleep . -
pubmed
[ The effects of immuno - chemotherapy ,
hyperthermia and irradiation on the growth of
human renal cell carcinoma ] . -
pubmed
In order to investigate more effective treatments for advanced
renal cell carcinoma , experiments were performed as to inhibitory effects on the growth of
KPK 1 cells derived from a
human renal carcinoma . -
pubmed
An investigation has been made with regard to the clinical picture of 87 terminally ill
patients with
lung cancer . -
pubmed
3 ) The most frequent cause of
death in these
patients was
respiratory failure , due to progress of
cancer , then
infection , pleural , or
pericardial effusion , or
interstitial pneumonitis . -
pubmed
Assessment of pancreatic islet - cell population in the
hyperglycemic athymic nude
mouse : immunohistochemical , ultrastructural , and hormonal studies . -
pubmed
Previous studies in
diabetic animal models have demonstrated altered pancreatic islet - cell populations . -
pubmed
To further characterize the
diabetic syndrome in our athymic nude
mouse colony , we studied the population of endocrine cells in pancreatic islets of 4 - week - old normoglycemic and 8 - week - old
hyperglycemic athymic nude ( nu / nu )
mice using immunohistochemistry , morphometry , and
electron microscopy . -
pubmed
The disposition and kinetics of intravenous
N - acetylcysteine in
patients with
paracetamol overdosage . -
pubmed
Seventeen
patients received standard treatment with intravenous
N - acetylcysteine for 18 episodes of severe
poisoning with
paracetamol (
acetaminophen ) . -
pubmed
The elimination of
N - acetylcysteine was not impaired in the
patients with severe
liver damage , and the pharmacokinetic variables and plasma concentrations were similar in
patients with and without
hepatotoxicity . -
pubmed
Percutaneous balloon valvuloplasty and coronary angioplasty for the treatment of
calcific aortic stenosis and obstructive
coronary artery disease in an elderly
patient . -
pubmed
An 81 - year - old
man with severe
calcific aortic stenosis and
coronary artery disease who refused surgical therapy was treated with sequential percutaneous balloon aortic valvuloplasty ( PBAV ) and percutaneous transluminal angioplasty . -
pubmed
Thus , combined therapy with
PBAV and PTCA is technically feasible in selected elderly
patients with
calcific aortic stenosis and anatomically suitable
coronary artery disease . -
pubmed
[ Comparison of the course of
chronic diarrhea without permanent damage of the mucosa of the small intestine with the course of
celiac disease in
children ] . -
pubmed
There is currently some concern over the potential risk to
man from its use , since it has been found to cause
liver tumours in
mice , following the administration of very large doses . -
pubmed
Following a single oral dose of 500 mg
cinnamyl anthranilate / kg
body weight to
B6C3F1 mice peak plasma levels of unchanged compound were reached in 30 min , and were higher in
males than in
females . -
pubmed
The histogenesis of
mammary tumours induced in the
rat by chemical carcinogens . -
pubmed
Letter : Studies of resistance to long - acting adrenergic beta - stimulators in
asthmatic patients . -
pubmed
Supercooling injury in the egg cell of the
sea urchin . -
pubmed
Since larvicidal treatment to reduce the numbers of
Culex fatigans , the tropical house mosquito , offers a promising means of preventing the spread of
filariasis , an assessment was made of the liability of
C. - pubmed
[
Dehydration of the
human organism at high altitudes ] . -
pubmed
[ Use of
digoxin in the treatment of
cardiac insufficiency in young
children with
congenital defects of the heart ] . -
pubmed
Intestinal ischemic shock in germ - free
animals . -
pubmed
Data from
patients were related to a control group of 38
patients with
gastrointestinal disease but without
pancreatic diseases . -
pubmed
[
Idiopathic thrombocytopenic purpura : diagnosis and therapy in 46
patients ] . -
pubmed
The hematological and immunological data of 46
patients with
idiopathic thrombozytopenic purpura (
ITP ) and their response to treatment are reported . -
pubmed
( 5 ) Fatal
hemorrhages are very rarely seen in
adults with
ITP . -
pubmed
Altered
tumor growth in vivo after immunization of
mice with antitumor antibodies . -
pubmed
A comparison has been made between the growth patterns of two spontaneously appearing
mammary adenocarcinomas in
murine bone marrow radiation chimeras and in
mice preimmunized with monoclonal antibodies ( MAb ) detecting embryo - associated antigenic determinants . -
pubmed
A correlation was seen between the ability of the
embryo - immunized chimeras to produce cytotoxic antibody to the
tumors , as assessed by an antibody - dependent cellular cytotoxic assay , and the permissiveness of the
mice for growth of a
tumor transplant . -
pubmed
In addition ,
mice deliberately preimmunized with cytotoxic MAb ( antibody - dependent cellular cytotoxic assay ) allowed more rapid growth specifically of that
tumor earlier found to be most sensitive to the MAb used for immunization . -
pubmed
By comparing the changing antigenic phenotype of
tumor cells serially passaged through different immunized , nonimmunized
mice , evidence was found suggesting that immunization could cause either antigen modulation of transferred
tumor cells or a ( transient ) selective advantage to antigenically discrete subpopulations within the heterogeneous
tumor population . -
pubmed
Finally , we have studied the growth pattern of
tumor cells transplanted into
mice immunized with
rabbit antibodies directed against the
murine MAb . -
pubmed
In this case ,
tumor growth was slowed preferentially for the
tumor reactive with the specific MAb , and again , predictable changes in the antigenic spectrum of
tumor cells harvested from these
animals were observed . -
pubmed
Our overall findings are interpreted in terms of the involvement of networks of antibodies reacting with embryo - associated antigens in the regulation of growth of the
murine mammary adenocarcinomas studied . -
pubmed
Maternal determinants of
oral clefts have been documented in studies of experimental animals but not of
humans . -
pubmed
The study documents the existence of maternal determinants of
CLP in
humans . -
pubmed
A
chronic vitamin B6 deficiency in
rats resulted in a non - specific increase ( 44- 51 % ) in the in vitro intestinal uptake of both essential (
Ca and
Zn ) and non - essential toxic metal (
Cd ) ions , whereas an acute B6 - deficient state only affected the
Zn uptake rate . -
pubmed
One
patient suffered sudden
chest pain shortly after an injection of
morphine , and one
patient had moderate
hypoventilation after
buprenorphine ; both
patients recovered uneventfully . -
pubmed
Human papillomavirus (
HPV ) specifically infect stratified epithelial cells , causing benign and
malignant neoplasia . -
pubmed
A comparative investigation of ultrastructural changes in the lungs of 28 cardiosurgical
patients operated upon under conditions of bubble and membrane oxygenation of blood has established that the following trends are perspective for lessening the disturbances of the lung ultrastructure in operations on the open heart : shorter time of the first parallel blood flow when using bubble oxygenation , less
trauma of the heart during artificial blood circulation due to the improved perfusion system , realization of the conditions of extrapulmonary oxygenation of blood , responsible for the prevention of hypoxic
injuries of the lungs . -
pubmed
Infectious osteitis pubis in an
HIV seropositive female . -
pubmed
These studies suggest that activated leukocytes produce vasoconstriction by the release of vasoactive factor(s ) , and thus may contribute to the pathogenesis of cardiovascular complications in
patients with
atherosclerosis . -
pubmed
Poliovirus type 1 isolated from a vaccine - associated case of
paralytic poliomyelitis in Brazil . -
pubmed
This study reports a type 1
poliovirus strain isolated in Brazil from a case classified as vaccine - associated
paralytic poliomyelitis (
VAPP ) . -
pubmed
The
patient 's parents , who are first cousins , are asymptomatic and have only minor reductions in
platelet aggregation . -
pubmed
Superficial , non - lethal
infection was produced in
mice by injecting
Pseudomonas aeruginosa into the skin windows . -
pubmed
It has been demonstrated that
MMC does not inhibit muscle reattachment and might inhibit adhesions and
scar formation in the
rabbit . -
pubmed
We investigated in a
rabbit model effectiveness of
MMC in reducing the formation of
postoperative adhesions following reoperations and the tensile strength of the new musculo - scleral junction . -
pubmed
We recently encountered a
patient with
thrombosis of the superior sagittal sinus of an idiopathic cause . -
pubmed
Whereas the
patient suffered a complication with subacute
subdural haematoma , he was successfully treated with the combination of these therapies . -
pubmed
Lesions associated with
infectious keratoconjunctivitis in
alpine ibex . -
pubmed
Following a severe
infectious keratoconjunctivitis (
IKC ) epizootic in free - ranging
alpine ibex (
Capra ibex ibex ) in Switzerland in 1993 , 19 animals were examined from six different populations . -
pubmed
The microbiological findings indicate that
Mycoplasma conjunctivae is the primary pathogenic agent causing
IKC in this species in Switzerland . -
pubmed
The patient was a 68 - year - old
man with no previous clinical history of
gastro - oesophageal reflux disease . -
pubmed
Patients with
LDLR defects had a significantly higher risk of
myocardial infarction , coronary artery bypass graft , positive coronary angiography ,
atherosclerotic plaques in the carotid arteries and
CAD ( p<0.01 ) than patients with
FDB . -
pubmed
CAD was present in 33 % and
plaques in the carotid arteries in 82 % of the
patients with
LDLR defects . -
pubmed
BACKGROUND : Because activation of platelets and of the coagulation system are interdependent mediators of
thrombosis , platelet activation was characterized in whole blood in the presence of anticoagulants used to assess platelet function in vitro or as treatment for
patients with
occlusive arterial disease . -
pubmed
An epithelial cell line ,
NPC - BM1 , was established from a bone marrow biopsy of a female
Taiwanese patient with
nasopharyngeal carcinoma (
NPC ) . -
pubmed
Histopathology of the bone marrow biopsy and xenografts grown in
severe combined immunodeficiency mice showed that the
tumor was a nonkeratinizing , poorly differentiated
carcinoma . -
pubmed
Further validation of
SV40 - like DNA in
human pleural mesotheliomas . -
pubmed
PATIENTS AND METHODS : During the period 1990 till 1997 , 292
patients underwent in our institution in total 354 ureteroscopies for
ureteric lithiasis . -
pubmed
Infants with
AIDS - related symptoms exhibited undetectable or very low levels of
HIV - specific cellular immunity during the first year of life , whereas those with a slowly progressive disease showed evidence of such immunity between their second and ninth month . -
pubmed
METHODS : A consecutive series of 374
patients who had a total of 409 anterior cervical arthrodeses for the treatment of
cervical spondylosis with
radiculopathy or
myelopathy , or both , were followed for a maximum of twenty - one years after the operation . -
pubmed
METHODS : In 45
patients with a high clinical likelihood of
renovascular hypertension (
RVH ) and unimpaired renal function , dynamic imaging was performed after an intravenous bolus injection of 148 MBq
( 99m ) Tc MAG3 for both baseline renoscintigraphy and
captopril renography following oral application of 50 mg
captopril . -
pubmed
RESULTS : The number of kidneys that had a change of & gt;/=5 % in RCA values was 12 ( 27.2 % ) in normal kidneys , 7 ( 58.3 % ) in the
patients with bilateral
RAS , 14 ( 82.3 % ) in the
patients with unilateral
RAS , and 21 ( 72.4 % ) in overall kidneys with
RAS . -
pubmed
Gruppo Italiano di Studi Epidemologici in Nefrologia ( Gisen ) In the
Ramipril Efficacy in
Nephropathy study ,
ramipril decreased the rate of
GFR decline ( deltaGFR ) and progression to
end - stage renal disease (
ESRD ) in 352
patients with
proteinuric chronic nephropathies . -
pubmed
Hepatoblastoma with
erythrocytosis in a young female
horse . -
pubmed
The prognosis for
horses with
hepatoblastoma is grave . -
pubmed
One - year follow - up of 2829
patients with moderate to severe
lower urinary tract symptoms treated with
alfuzosin in general practice according to IPSS and a health - related quality - of - life questionnaire . -
pubmed
OBJECTIVES : To determine the effectiveness of
alfuzosin on symptom reduction ,
patients ' perceived health - related quality of life ( HRQL ) improvement , adverse outcomes , treatment failure , and progression to acute urinary retention and prostate surgery in
patients with
lower urinary tract symptoms suggestive of
benign prostatic hyperplasia (
BPH ) in a 1 - year prospective , open - labeled study . -
pubmed
CONCLUSIONS : This study confirms the effectiveness of
alfuzosin and the need to include HRQL measurement in the decision - making process when assessing
patients with
lower urinary tract symptoms . -
pubmed
A multiplex PCR was employed to amplify unique conserved sequences of DNA from the pathogens
Haemophilus influenzae ,
Neisseria meningitidis and
Streptococcus pneumoniae from cerebrospinal fluid samples of
patients suffering from acute
pyogenic meningitis . -
pubmed
Ten single - rooted teeth from 8
patients with advanced adult
periodontitis were included . -
pubmed
The impact of
liver dysfunction on outcome in
patients with
multiple injuries . -
pubmed
To clarify the role of the
hepatic dysfunction after
traumatic injury we retrospectively reviewed all
trauma patients with an Injury Severity Score & gt ; or = 14 admitted from January 1 , 1994 through June 30 , 1997 for the presence of
hepatic dysfunction defined as a serum
bilirubin & gt ; or = 2.0 mg / dL. -
pubmed
Of the 1962
patients who met the entry criteria 154 developed
hepatic dysfunction during their hospital stay . -
pubmed
Patients with
hepatic dysfunction were older ( 46 + /- 2 versus 41 + /- 1 years ) , were more severely injured (
Injury Severity Score 31.5 + /- 0.9 versus 23.3 + 0.2 ) , and had a lower prehospital blood pressure ( 102 + /- 3 versus 117 + /- 1 mm Hg ) compared with
patients who did not develop
hepatic dysfunction . -
pubmed
Patients with
hepatic dysfunction were more likely to present with
shock as reflected in a lower initial emergency room blood pressure ( 109 + /- 3 versus 128 + /- 1 mm Hg ) and base deficit ( -6.9 + /- 0.6 versus -3.5 + /- 0.1 mEq / L ) . -
pubmed
Perfusion brain SPECT and statistical parametric mapping analysis indicate that
apathy is a
cingulate syndrome : a study in
Alzheimer ' s disease and nondemented
patients . -
pubmed
According to ICD 10 diagnostic criteria , 28
patients had
Alzheimer dementia (
demented : diagnostic group 1 ) , and 13 had
organic personality disorders or mild
cognitive impairment not attributable to
dementia ( nondemented : diagnostic group 2 ) . -
pubmed
Separation of free
amino acids in
human plasma by capillary electrophoresis with laser induced fluorescence : potential for emergency diagnosis of
inborn errors of metabolism . -
pubmed
Amino acid profiles for both normal donor plasma samples and plasma samples of
patients suffering from
phenylketonuria ,
tyrosinemia ,
maple syrup urinary disease ,
hyperornithinemia , and
citrullinemia are studied . -
pubmed
We report a 69 years old
woman with a history of one month of
vertigo ,
nausea ,
vomiting and
diarrhea . -
pubmed
At the 4th day of admission , the
patient was again
stuporous and with
spastic quadriplegia . -
pubmed
RESULTS : Omalizumab treatment resulted in significantly fewer
asthma exacerbations per subject and in lower percentages of
subjects experiencing an exacerbation than placebo treatment during the stable
steroid phase ( 0.28 vs 0.54 [ P = .006 ] and 14.6 % vs 23.3 % [ P = .009 ] , respectively ) and during the
steroid reduction phase ( 0.39 vs 0.66 [ P = .003 ] and 21.3 % vs 32.3 % [ P = .004 ] , respectively ) . -
pubmed
Prediction of wall motion recovery from the left anterior descending coronary artery velocity pattern recorded by transthoracic doppler echocardiography in
patients with anterior wall
myocardial infarction retrospective and prospective studies . -
pubmed
Patients with a shorter DHT of diastolic coronary flow velocity have a poorer functional outcome among
patients with anterior
AMI . -
pubmed
Role of the serotoninergic system in the acceleration of sexual maturation in wild
Norway rats selected for reduced
aggressiveness toward
humans . -
pubmed
They also suggest that the acceleration in sexual maturation of domesticated
rats could result from changes in the ontogenetic dynamic of hypothalamic
serotonin induced by a selection for low
aggressiveness towards
man . -
pubmed
Psoriasis is recognized as the most common
T cell - mediated inflammatory disease in
humans . -
pubmed
The disease - related gene map provides new insights into the pathogenesis of
psoriasis ,
wound healing and cellular - immune reactions occurring in
human skin as well as other T cell - mediated
autoimmune diseases . -
pubmed
Preparing
patients with
asthma for discharge . -
pubmed
Kava - induced
fulminant hepatic failure . -
pubmed
Here we report that a Wolbachia
strain feminizes an insect host ,
Ostrinia furnacalis . -
pubmed
The present findings indicate that the
Wolbachia infection induces
feminization of genetic males in
O. - pubmed
Differences in the Wolbachia - induced
feminization in
O. - pubmed
Our findings over 5 years suggest that the
infection has been maintained at a low prevalence in the
O. - pubmed
[ OSCILLOGRAPHIC STUDIES IN
PATIENTS WITH
CHRONIC LUNG DISEASES ] . -
pubmed
[ SERO - EPIDEMIOLOGICAL INVESTIGATION OF
ADENOVIRUS INFECTIONS MADE WITH THE GEL DIFFUSION METHOD ] . -
pubmed
The objectives were to determine the sociodemographic profile , risk category , and prevalence of
HIV infection amongst people attending a confidential clinic providing counselling , medical advice and results of
HIV antibody testing on the same day of consultation . -
pubmed
Thirty of the
HIV antibody - positive individuals were asymptomatic , 14 were symptomatic and three were diagnosed with an
AIDS - defining condition . -
pubmed
The continuing high
HIV seroprevalence among individuals from African countries suggests that this population require specific targeting for
HIV risk reduction and information on the advantages of early diagnosis and treatment . -
pubmed
Infection studies on
human cell lines with
porcine circovirus type 1 and
porcine circovirus type 2 . -
pubmed
Infection of
PCV1 was observed with
293 ,
Hela and Chang liver cells ,
infection with
PCV2 only in
Rd cells . -
pubmed
When virus - free cells were inoculated with the supernatant of
PCV - infected
human cells , the
infection was not passed . -
pubmed
CONCLUSION : Although PCV gene expression and replication took place in
human cells , the
infection is non - productive . -
pubmed
Because of the uncertain predictive value of
animal models of
neuropathic pain , it is essential to consider rational strategic approaches to selecting the most likely candidate targets . -
pubmed
RESULTS : There were 20 female
patients undergoing surgical treatment for
PAOD during the study period , aged from 57 to 91 years , with an average of 73.7 + /- 2.2 . -
pubmed
Four
patients presented with
rest pain . -
pubmed
Twelve
patients presented with
gangrene of lower limbs . -
pubmed
CONCLUSIONS : The female
patients of
PAOD presented with severe symptoms and advanced Fontaine stages . -
pubmed
Management of
cryptococcal meningitis with extremely high intracranial pressure in
HIV - infected patients . -
pubmed
CONCLUSION :
Octreotide scintigraphy is useful in localizing occult
carcinoid tumors and can be used in the follow - up of
patients after successful removal of these
tumors . -
pubmed
We report on a 21 - year - old
man who presented with left testicular
swelling and
pyogenic discharge from the scrotum . -
pubmed
METHODS : We performed a prospective study of 13
patients with
dermatochalasis who underwent radiosurgery in one upper eyelid and conventional surgery with scalpel and scissors in the contralateral eyelid . -
pubmed
Psychostimulant - induced behavior as an
animal model of
obsessive - compulsive disorder : an ethological approach to the form of
compulsive rituals . -
pubmed
Moreover , in both
quinpirole - treated
rats and
OCD patients , the structure of
compulsive rituals appear similar in being composed of relatively few motor acts that are organized in a flexible yet recurrent manner . -
pubmed
In addition , the development of
compulsive behavior in
quinpirole - treated
rats is attenuated by the OCD pharmacotherapeutic drug
clomipramine . -
pubmed
These similarities support the validity of
quinpirole - treated
rats as a psychostimulant - induced
animal model of
OCD . -
pubmed
Partial splenectomy is the preferred technique because of the short- and long - term
sepsis problems in asplenic
patients . -
pubmed
CONCLUSION : Partial splenectomy was achieved in the
ovine spleen using radiofrequency energy with minimal
blood loss . -
pubmed
SUBJECTS AND METHODS : A group of eight
patients from the pulmonary clinic in Rabin Medical Center with a combine presentation of
fibrosis and
emphysema was identified retrospectively . -
pubmed
RESULTS :
Upper - lobe emphysema with bulluos changes was found in all
patients . -
pubmed
Most of the
patients had moderate - to - severe
pulmonary hypertension as well as diffuse
coronary artery disease . -
pubmed
The aim of this study was to assess the effect of thermal stimuli or distal scratching on skin blood flow and
histamine - induced
itch in healthy
volunteers . -
pubmed
Diagnostic value of gall bladder wall thickness in
patients with
ascites . -
pubmed
A retrospective study was performed on 841
patients with
endometrial cancer , who underwent the initial surgery at the Keio University Hospital . -
pubmed
Among the 155
patients who underwent pelvic and para - aortic lymph node dissection , the difference of 5 - year overall survival by the presence of retroperitoneal lymph node
metastasis was examined by Kaplan - Meier method . -
pubmed
MATERIAL : 40
patients after spine surgery because of
low back pain and 20 persons of control group participated in the study . -
pubmed
Moreover ,
tumors collected from 40
dogs in 5 continents are derived from a single neoplastic clone that has diverged into two subclades . -
pubmed
Phylogenetic analyses indicate that
CTVT most likely originated from a
wolf or an East Asian breed of
dog between 200 and 2500 years ago . -
pubmed
Photodynamic therapy of experimental
choroidal neovascularization in the
mouse . -
pubmed
PURPOSE : To evaluate the qualitative and quantitative effects of
verteporfin photodynamic therapy ( PDT ) on laser - induced
choroidal neovascularization (
CNV ) in the
mouse . -
pubmed
However , PDT - treated areas will remain vascularized with continued growth of the CNV lesion , which in turn may explain the often limited effect of PDT in
patients with neovascular age - related
macular degeneration . -
pubmed
MATERIAL AND METHODS : 15
patients with
cystic fibrosis and 15 control
subjects were included in this study . -
pubmed
We report a 23 - year - old
patient undergoing functionally univentricular repair who developed
cardiac failure due primarily to systemic
ventricular dysfunction . -
pubmed
Aortic counterpulsation facilitates recovery of systemic ventricular function , and appears to be a reasonable alternative in select instances of
cardiac failure in
patients with the Fontan circulation . -
pubmed
CA revealed
CAD in 25
patients . -
pubmed
MATERIALS AND METHODS : The charts of
children diagnosed with
PPU at our hospital from January 1986 to June 2005 were reviewed . -
pubmed
Nine
patients ( 17.3 % ) had
postoperative complications . -
pubmed
The summary risk ratio for contrast - related
nephropathy was 0.69 ( 95 % confidence interval : 0.57 to 0.82 ; P = 0.02 ) , a statistically significant trend towards benefit in
patients treated with
N - acetylcysteine . -
pubmed
Demographically adjusted normative standards were derived from a sample of 182 seronegative healthy participants and were subsequently applied to a sample of 135
HIV-1 seropositive individuals with multidisciplinary case conference diagnoses of
HIV-1 - associated
neurocognitive disorders ( e.g. -
pubmed
Patients with
multiple myeloma (
MM ) have increased bone marrow angiogenesis , but the angiogenic properties of
myeloma cells and the mechanism of MM - induced angiogenesis have not been completely clarified . -
pubmed
Finally , our in vitro results were supported by the in vivo finding in
human myeloma xenograft NOD / SCID models . -
pubmed
[ Parameters of hypothalamo - pituitary - adrenal , thyroid and genital systems in
patients with
occupational allergic dermatosis ] . -
pubmed
This article describes the case of a
patient who presented with an open , comminuted first metatarsal
fracture as a result of a
chainsaw injury . -
pubmed
The
patient was treated with a uniplanar mini - external fixator , demineralized bone matrix , primary
wound closure , and external bone growth stimulation . -
pubmed
Intravitreal
bevacizumab (
avastin ) as a treatment for
refractory macular edema in
patients with
uveitis : a pilot study . -
pubmed
CONCLUSIONS : In
uraemic rats with established
secondary hyperparathyroidism , we demonstrate differential effects of
paricalcitol and
doxercalciferol on
aortic calcification and PWV , independent of serum
Ca , P and
Ca x P , suggesting different mechanisms of action between VDRAs . -
pubmed
Carbon monoxide poisoning in
children . -
pubmed
BACKGROUND :
Carbon monoxide (
CO ) is an important source of
poisoning in
children . -
pubmed
We performed this study in order to clarify the clinical characteristics of pediatric
patients with
CO poisoning . -
pubmed
METHODS : We identified and reviewed the medical records of pediatric
patients diagnosed with
CO intoxication and hospitalized in our department during a 10 - year period . -
pubmed
RESULTS : A total of 30
children with
CO poisoning were identified . -
pubmed
Seizures during the acute stage , severe
metabolic acidosis , significant
hypotension , longer times for recovery to full consciousness , and longer hospital stays were observed in
children with
DNS . -
pubmed
CONCLUSION :
Children with
CO poisoning had good outcomes in this series . -
pubmed
CONCLUSIONS : When used with socially anxious
adolescents , VF may be a beneficial therapeutic technique in correcting a distorted self - perception of performance , reducing
anxiety prior to entering a stressful social task and enhancing predictions of performance for future tasks . -
pubmed
In order to clarify the role of
Gnathostoma turgidum as an etiological agent involved in
human gnathostomiasis in Mexico , establish the taxonomic identity of the advanced third - stage larvae ( AdvL(3 ) ) , and contribute to the knowledge of its life cycle , experimental host
infections , examination of potential natural hosts , and morphological comparisons were carried out . -
pubmed
129 / SV
mice were subjected to 30 min filamentous
middle cerebral artery occlusion (
MCAo ) , followed by reperfusion . -
pubmed
The present study was designed to use stem cells preconditioned with
trimetazidine (
1 -[ 2,3,4 - trimethoxybenzyl ] piperazine ;
TMZ ) , a widely used anti - ischemic drug for treating
angina in cardiac
patients , to increase the rate of their survival after transplantation . -
pubmed
Bone marrow - derived
rat mesenchymal stem cells ( MSCs ) were subjected to a simulated host tissue environment by culturing them under
hypoxia ( 2 %
O ( 2 ) ) and using
hydrogen peroxide (
H ( 2 ) O ( 2 ) ) to induce oxidative stress . -
pubmed
The therapeutic efficacy of the
TMZ - preconditioned MSCs was evaluated in an in vivo
rat model of
myocardial infarction induced by permanent ligation of left anterior descending coronary artery . -
pubmed
Acute light - induced
photoreceptor degeneration has been studied in experimental
animals as a model for photoreceptor cell loss in
human retinal degenerative diseases . -
pubmed
We investigated the hypothesis that various antidiabetic drugs had differential direct impact on
cancer cells using four
human cell lines (
pancreatic cancer :
MiaPaCa2 ,
Panc-1 ;
breast cancer :
MCF7 ,
HER18 ) . -
pubmed
This study provides experimental evidence to support further investigation of
metformin and
rosiglitazone as first - line therapies for
type 2 diabetes in
cancer patients . -
pubmed
CUMS - induced
depression model was established in
Sprague - Dawley rats . -
pubmed
The results showed that , compared with the control group ,
rats receiving CUMS for 21 d or intrahippocampal microinjection of
GR231118 showed a significant reduction in
body weight and
depression - like behavior , which included reductions in
sucrose preference , locomotor activity , rearing and grooming in open field test , and increased duration of immobility in forced swimming test . -
pubmed
METHODS : In this prospective , correlational study , SbpO(2 ) , SaO(2 ) , and
SpO ( 2 ) values were recorded at
normoxemia and at three
hypoxemic conditions ( SpO(2)=90 % , 80 % , and 70 % ) for 53 healthy , nonsmoking
adults who were without
cardiac or pulmonary disease , baseline
hypoxemia ,
peripheral edema ,
dyshemoglobinemia , and
fever . -
pubmed
Transplantation of umbilical cord mesenchymal stem cells alleviates
lupus nephritis in
MRL / lpr mice . -
pubmed
Systemic lupus erythematosus (
SLE ) is a multisystem
autoimmune disease , which , despite the advances in immunosuppressive medical therapies , remains potentially fatal in some
patients , especially in treatment - refractory
patients . -
pubmed
This study found that transplantation of umbilical cord mesenchymal stem cells ( UC - MSCs ) has the same therapeutic effect as transplantation of bone marrow mesenchymal stem cells ( BM - MSCs ) , which has been reported to be efficient in treating
SLE - related symptoms in
MRL / lpr mice . -
pubmed
Multi - treatment ( at the 18th , 19th , and 20th weeks of age ) of 1 x 10(6 ) UC - MSCs was able to decrease the levels of 24 - h
proteinuria , serum
creatinine , and anti - double - stranded DNA ( dsDNA ) antibody , and the extent of
renal injury such as crescent formation in
MRL / lpr mice . -
pubmed
When do asymmetrical full - field pattern reversal visual evoked potentials indicate
visual pathway dysfunction in
children ? -
pubmed
In this study we perform laser - induced axotomy of the
porcine retinal
ganglion cell axon , a physiologically unmyelinated , mature CNS axon that is structurally similar to
humans to infer knowledge about axonal behaviour in the absence of myelin . -
pubmed
Filtrates of 57 staphylococci showed strong activity against
Listeria monocytogenes Scott A , and 52 isolates also inhibited the growth of
Stapylococcus aureus Newbould 305 , a major causative agent of
bovine mastitis in the United States . -
pubmed
Over the past 60 years , investigators of basic science , pathology , and clinical medicine have studied
gastrointestinal stromal tumor (
GIST ) and made minor advances in
patient care . -
pubmed
Age - related changes in
genomic stability of
horses . -
pubmed
Here , we show that breed - independent and age - associated changes in
genomic stability may contribute , at least in part , to the aging process in the
horse . -
pubmed
We report the conjugation of the C - terminal alpha - helix of
human melanoma growth stimulating activity to
daunorubicin using the novel linker
polyethylene glycol ( 3400 )
dialdehyde . -
pubmed
METHODS : One hundred and sixty - three female pregnant kunming
mice were randomly divided into 6 groups , including A , control group ; B , ovulation stimulation ( OS ) group ; C , OS+TCM group ; D , embryo implantation dysfunction (
EID ) group ; E , EID+TCM group ; F , TCM only group . -
pubmed
A prospective study of fifty
patients who underwent
cataract surgery with intraocular lens ( IOL ) implantation was undertaken . -
pubmed
We report a case of a 25 - year - old
woman who presented with a small intestinal
angiosarcoma associated with
angiosarcomatosis . -
pubmed
Instead of its usage when antegrade recanalization failed , the " facedown " technique was preferred as a first choice in
patients with common
femoral artery stenosis or occlusion , proximal lesions of the superficial femoral artery ( SFA ) with no stump , severe
obesity , tandem iliac , and SFA lesions . -
pubmed
Stapler access and visibility in the deep pelvis : A comparative
human cadaver study between a computerized right angle linear cutter versus a curved cutting stapler . -
pubmed
Noncontrast techniques for peripheral MR angiography are receiving renewed interest because of safety concerns about the use of
gadolinium in
patients with
renal insufficiency . -
pubmed
Persistent
hyperglycemia at 24 - 48 h in acute
hyperglycemic stroke patients is not associated with a worse functional outcome . -
pubmed
METHODS : We analyzed all
patients with
glucose & gt;7.3 mmol / l on admission from the
Acute STroke Registry and Analysis of Lausanne ( ASTRAL ) . -
pubmed
RESULTS : A total of 1,984
patients with
ischemic stroke were admitted between January 1 , 2003 and October 20 , 2009 , within 24 h after last well - being time . -
pubmed
In multiple logistic regression analysis , unfavorable outcome was significantly associated with age ( odds ratio , OR : 1.06 , 95 % confidence interval , 95 % CI : 1.03 - 1.08 for every 10 - year increase ) , National Institute of Health
Stroke Score , NIHSS score , on admission ( OR : 1.16 , 95 % CI : 1.11 - 1.21 ) , prehospital mRS ( OR : 12.63 , 95 % CI : 2.61 - 61.10 for
patients with score & gt;0 ) , antidiabetic drug usage ( OR : 0.36 , 95 % CI : 0.15 - 0.86 ) and
glucose on admission ( OR : 1.16 , 95 % CI : 1.02 - 1.31 for every 1 mmol / l increase ) . -
pubmed
CONCLUSIONS : In
ischemic stroke patients with acute
hyperglycemia , persistent
hyperglycemia ( & gt;7.3 mmol / l ) at 24 - 48 h after
stroke onset is not associated with a worse functional outcome at 3 months whether the patient was previously
diabetic or not . -
pubmed
Originally discovered by McCay 's group in the 1930s , this paradigm showed that
animals placed on the DR regimen , meaning reduced nutrition without
malnutrition , had robust life extensions ( 1 ) . -
pubmed
We present a rare case of combined
fungal infection in a critically ill 47 year - old
patient with
chronic hepatitis C at the stage of
liver cirrhosis . -
pubmed
MATERIALS AND METHODS : 130
patients ( 87 male and 43 female ; age range 49 - 86 years , mean 71.1 ) were selected whose diagnoses were pathologically confirmed as
CRC with
schistosomiasis . -
pubmed
Linear , spotty and small patchy
calcifications were seen in 104 ( 80.0 % ) patients , with unclear margins in 96
patients . -
pubmed
The
tumors were markedly unevenly enhanced in 92
patients . -
pubmed
Pathological examination revealed
adenocarcinoma in 114
patients and in 104
patients , calcified
Shistosoma japonicum (
S. - pubmed
japonicum ) ova inside the
tumors , 15
patients were
mucinous adenocarcinoma , and one patient was that of adenosquamous
carcinoma . -
pubmed
We report a 4 - year - old
girl presenting with sudden severe bilateral
visual loss . -
pubmed
Studying the effect of
IBD susceptiblity gene dysfunctions in tissue cultures and
animal models will allow the ultimate translational benefits of developing novel treatments for and potentially preventing
IBD in those having specific genetic risk factors . -
pubmed
Electrophysiological and motor function scale association in a pre - symptomatic
infant with
spinal muscular atrophy type I. -
pubmed
There was no significant effect of individual GM6 and KM genotypes on the risk of
PM infection in
HIV-1 negative and positive women . -
pubmed
However , the combination of homozygosity for GM6(+ ) and KM3 was associated with decreased risk of
PM ( adjusted OR , 0.25 ; 95 % CI , 0.08 - 0.8 ; P = 0.019 ) in HIV-1 negative women while in
HIV-1 positive women the combination of GM6(+/- ) with either KM1 - 3 or KM1 was associated with increased risk of
PM infection ( adjusted OR , 2.10 ; 95 % CI , 1.18 - 3.73 ; P = 0.011 ) . -
pubmed
These findings suggest that the combination of homozygous GM6(+ ) and KM3 may protect against
PM in
HIV-1 negative women while the
HIV-1 positive women with heterozygous GM6(+/- ) combined with KM1 - 3 or KM1 may be more susceptible to
PM infection . -
pubmed
Breaking Barriers to an
AIDS Model with Macaque - Tropic
HIV-1 Derivatives . -
pubmed
The development of an animal model of
human immunodeficiency virus type 1 ( HIV-1 )/ AIDS that is suitable for preclinical testing of antiretroviral therapy , vaccines , curative strategies , and studies of pathogenesis has been hampered by the
human - specific tropism of
HIV-1 . -
pubmed
In this review , we discuss recent findings regarding
HIV-1 restriction factors , particularly as they apply to cross - species transmission of primate lentiviruses and the development of a macaque model of
HIV-1 /
AIDS . -
pubmed
The prognostic role of late
gadolinium enhancement magnetic resonance imaging in
patients with
cardiomyopathy . -
pubmed
Cardiovascular magnetic resonance imaging ( CMRI ) is currently considered part of standard care at many academic centres for the evaluation of
patients with ischemic or
nonischemic cardiomyopathy . -
pubmed
Given the low specificity of currently available clinical markers in
patients with
cardiomyopathy , more - robust biomarkers aimed at identifying those at high risk of
sudden cardiac death and other relevant outcomes are desirable . -
pubmed
This review paper focuses on the evidence to date supporting LGE imaging as a tool for the prediction of future cardiovascular events in
patients with ischemic and
nonischemic cardiomyopathy . -
pubmed
CASE DESCRIPTION : A 44 - year - old
male presented with complaints of left - sided retro - orbital
pain ,
double vision , and
numbness over the upper face and scalp on the left side of 1 - week duration . -
pubmed
OBJECTIVE : Extracts from 16 plants identified and selected from the ethnomedicine of the Ijebus in Southwestern Nigeria as remedies for
tuberculosis were evaluated for activity against
Mycobacterium tuberculosis , in vitro . -
pubmed
PURPOSE OF REVIEW : In
multiple sclerosis (
MS ) , symptoms vary widely from patient to
patient . -
pubmed
Furthermore , following administration of
APP96 - 110 in
rats after diffuse impact acceleration
TBI , motor and cognitive outcomes were significantly improved and
axonal injury reduced . -
pubmed
Renal denervation prevents
stroke and
brain injury via attenuation of oxidative stress in
hypertensive rats . -
pubmed
Sipuleucel - T is an antigen - presenting cell - based active immunotherapy that utilizes a
patient 's own immune cells , presumably to activate an antigen - specific immune response against
tumor cells . -
pubmed
METHODS : A retrospective cohort study was performed to include pediatric
patients presenting with
headache fulfilling the International Classification of
Headache Disorders-2
migraine criteria in a tertiary care ( site 1 ) and a community based ( site 2 ) emergency department . -
pubmed
[ Management of
Fournier ' s gangrene in
HIV - positive patients : report of 29 cases ] . -
pubmed
OBJECTIVE : To review the clinical characteristics and treatment strategies of
Fournier ' s gangrene in
HIV - positive patients . -
pubmed
METHODS : We retrospectively analyzed the clinical characteristics and therapeutic methods of 29
HIV - positive cases of
Fournier ' s gangrene . -
pubmed
The two aged
patients were complicated by
diabetes mellitus . -
pubmed
Twenty - six of the
patients were recovered and the other 3 ( 10.3 % ) died after surgery , 1 from
infectious shock and 2 from
diabetes mellitus complicated by
pulmonary infection and
renal failure . -
pubmed
CONCLUSION : Timely aggressive surgical debridement , incision - drainage and broad - spectrum antibiotic medication are essential for the treatment of
Fournier ' s gangrene in
HIV - positive patients . -
pubmed
We also investigated the effects of these drug combinations on
tumor growth in a
nude mouse xenograft model . -
pubmed
Finally , treating
mice - bearing
RMG - I with
AZD7762 and
cisplatin significantly suppressed growth of
tumors in a xenograft model . -
pubmed
CONCLUSIONS : The present study indicates that chemotherapy with
AZD7762 and
cisplatin should be explored as a treatment modality for
women with
ovarian clear cell carcinoma . -
pubmed
NMD modulates the clinical outcome of a variety of
human diseases , including
cancer and many
genetic disorders , and may represent a target for therapeutic intervention . -
pubmed
RESULTS : Number of
patients who developed
sore throat was significantly higher in the
Succinylcholine group ( 75 % ) compared to
Cisatracurium group ( 27.5 % ) at the time of entrance to the recovery room ( P = 0.001 ) . -
pubmed
RESULTS : The study included 2679
CAC and 1135 Reference
patients . -
pubmed
Here , we review the various phenotypic traits that have been proposed to be affected by the highly parasitic
human environment , including fertility ,
birth weight , fluctuating asymmetry , body odours , food recipes , sexual behaviour , pregnancy sickness , language , religion and intellectual quotient . -
pubmed
Technique selection should be tailored to each individual case on the basis of
tumour characteristics , surgical feasibility , surgeon experience ,
patient demographics and baseline renal function . -
pubmed
WITHDRAWN :
Superoxide generation in different brain regions of
rats during normoxia and
hypoxia - reoxygenation . -
pubmed
Staphylococcus aureus induces
hypoxia and cellular damage in
porcine dermal explants . -
pubmed
Predominant bands related to
lactic acid bacteria , such as
Lactococcus and
Lactobacillus strains , were sequenced from the DGGE patterns of fish fed the probiotic diet , whereas they were not sequenced from fish receiving the control diet . -
pubmed
Functionally , the effects of D+I were tested in
glaucomatous rats . -
pubmed
BACKGROUND :
GAMT deficiency is an
autosomal recessive disorder of
creatine biosynthesis causing
developmental delays or
intellectual disability in untreated
patients as a result of irreversible
brain damage occurring prior to diagnosis . -
pubmed
The newborn screening for
GAMT deficiency should be implemented to identify
patients at the asymptomatic stage to achieve normal neurodevelopmental outcome for this treatable
neurometabolic disease . -
pubmed
Patients with & gt;10 coronal curves , significant
sagittal malalignment ,
infection , and preoperative instrumentation failure were excluded . -
pubmed
Complications included asymptomatic cage migration alone ( two patients )
neurological decline ( two
patients ) and
epidural hematoma ( one patient ) . -
pubmed
CONCLUSIONS : The major new finding from this study is that
HHcy induced a marked increase in PE - induced contraction in
rat corpus cavernosum by a mechanism that involves increased
O2 (- ) generation and it could play a role in the pathogenesis of
erectile dysfunction associated with
HHcy . -
pubmed
A prospective observational study was conducted to correlate EUS evaluation of
paraesophageal varices , azygos vein , and thoracic duct with variceal
recurrence after EBL variceal eradication in
patients with
cirrhosis . -
pubmed
Seventeen
patients ( 57 % ) presented variceal
recurrence . -
pubmed
The emergence of
Mycobacterium tuberculosis strains that are resistant to the current anti -
tuberculosis ( TB ) drugs necessitates a need to develop a new class of drugs whose targets are different from the current ones . -
pubmed
The equilibrium between the ventricular and lumbar cerebrospinal fluid ( CSF ) compartments may be disturbed ( in terms of flow and biochemistry ) in
patients with
chronic hydrocephalus (
CH ) . -
pubmed
OBJECTIVE : Recent studies have demonstrated improved outcomes in
patients receiving early surgery for
degenerative mitral regurgitation (
MR ) rather than adhering to conventional guidelines for surgical intervention . -
pubmed
METHODS : One hundred and fifty - one
patients with unilateral
osteonecrosis of the femoral head were enrolled consecutively for current prospective study from January to August of 2006 . -
pubmed
Curcumin Monoglucoside Shows Improved Bioavailability and Mitigates
Rotenone Induced
Neurotoxicity in Cell and
Drosophila Models of
Parkinson ' s Disease . -
pubmed
Based on these data , we surmise that
CMG has improved bioavailability and offered neuroprotection comparable with
CUR , against
ROT - induced
toxicity both in dopaminergic neuronal cell line and
Drosophila models , with therapeutic implications for
PD . -
pubmed
Traditionally , myeloid - derived suppressor cells ( MDSC ) have been studied in regard to their increased numbers of circulating cells in
cancer patients . -
pubmed
The expanded population of DC - HIL(+ ) Mo - MDSC in
psoriasis patients , however , display inferior suppressive capabilities compared to DC - HIL(+ ) Mo - MDSC found in
melanoma patients , suggesting contextual signaling as a potential contributing factor to Mo - MDSC function . -
pubmed
METHOD AND RESULTS : A 44 - year - old
man was admitted due to severe
epigastric pain . -
pubmed
The
patient was diagnosed with
non - small cell lung cancer 9 months ago and received 6 cycles of chemotherapy with
motesanib ,
paclitaxel , and
carboplatin . -
pubmed
The synthetic BSeDs were identified as potent antiproliferative agents against the
human MCF-7 and
MDA - MB-231 breast cancer cell lines . -
pubmed
HIV-1 promotes a generalized immune activation that involves the main targets of
HIV-1 infection but also cells that are not sensitive to
viral infection . -
pubmed
In vivo studies have failed to demonstrate the presence of replicating virus in ECs suggesting that a direct role of the virus is unlikely , and implying that the mechanism accounting for
vascular dysfunction may rely on the indirect action of molecules released in the microenvironment by
HIV-1 - infected cells . -
pubmed
In particular , we discuss the emerging role played by different
HIV-1 proteins in driving
inflammation and EC dysregulation , and highlight the need to target them for therapeutic benefit . -
pubmed
The results demonstrate the larval
zebrafish model as a useful tool in the study of intrinsic cardiac activity and its role in
heart diseases . -
pubmed
Therefore the aim of the present work was to investigate the effects of
SMF on autonomic cardiovascular control in adult spontaneously
hypertensive rats . -
pubmed
MATERIALS AND METHODS : Experiments were performed in freely moving spontaneously
hypertensive rats equipped with femoral arterial catheter for blood pressure recording . -
pubmed
A control group of spontaneously
hypertensive rats ( n = 17 ) was not exposed to
SMF . -
pubmed
The aim of this study is to investigate overweight , as a predictor of brace results in
AIS patients . -
pubmed
Influence of the Valsalva maneuver on cardiac hemodynamics and right to left shunt in
patients with
patent foramen ovale . -
pubmed
The purpose of this study was to investigate the influence of the Valsalva maneuver ( VM ) on cardiac hemodynamics in
patients with
patent foramen ovale (
PFO ) . -
pubmed
Sixty - five
patients who were highly suspected to have
PFO were included . -
pubmed
The results showed that JA - treated
sugarcane did not affect the
weight gain of the two larvae . -
pubmed
Here , using the pooling sequencing - based methodology , we deciphered the genetic basis for the varied silk production in different
silkworm strains . -
pubmed
A Profile of Individuals with Anti -
tobacco Message
Fatigue . -
pubmed
OBJECTIVES : Message
fatigue , a phenomenon of being tired of repeated exposure to messages promoting the same health behavior , may reduce the effectiveness of anti -
tobacco messages , such as warning labels . -
pubmed
METHODS :
Liver Fibrosis was induced in
mice by
carbon tetrachloride (
CCl4 ) . -
pubmed
Immunohistochemical staining using tissue microarray with 312 samples from randomly selected
patients with
HCC who underwent surgery . -
pubmed
The neurorestorative effect of
human amniotic fluid stem cells on the chronic phase of neonatal
hypoxic - ischemic encephalopathy in
mice . -
pubmed
However , the efficacy of
human amniotic fluid stem cells ( hAFS ) for
HIE , especially in the chronic phase , remains unclear . -
pubmed
HI was induced in 9 - day - old
mice . -
pubmed
CONCLUSION : hAFS induced functional recovery by exerting neurorestorative effects in
HIE mice , suggesting that intranasal administration of hAFS could be a novel treatment for
HIE , especially in the chronic phase . -
pubmed
Patients were classified based on the coexisting
liver disease at the time of
HF , ie , no
liver disease ,
noncirrhotic liver disease , and
liver cirrhosis . -
pubmed
Results : Among 152,180
HF patients , 2,552 ( 1.7 % ) patients had noncirrhotic
liver disease and 1,866 ( 1.2 % ) patients had
liver cirrhosis . -
pubmed
Thirty - day mortality was 9.4 % among
patients with noncirrhotic
liver disease , 12.6 % among patients with
liver cirrhosis patients , and 9.7 % among patients without
liver disease . -
pubmed
Conclusion :
Liver disease patients , especially those with
liver cirrhosis , had increased 30 - day mortality and 31 - 365 - day mortality following
HF , compared to patients without
liver disease . -
pubmed
However , there are also various concerns or limitations over the use of natural materials derived from
animals or
cadavers , including the potential immunogenicity , pathogen transmission , batch to batch consistence and mismatch in properties for various applications . -
pubmed
METHODS : We analyzed
SCFA levels by high - performance liquid chromatography ( HPLC ) in fecal samples from 301 one - year - old
children from a birth cohort and examined their association with early life exposures , especially diet , and
allergy and
asthma later in life . -
pubmed
In addition , we treated
mice with SCFAs to examine their effect on
allergic airway inflammation . -
pubmed
Children with the highest levels of
butyrate and
propionate ( & gt;=95th percentile ) in feces at the age of one year had significantly less
atopic sensitization and were less likely to have
asthma between 3 and 6 years . -
pubmed
Children with the highest levels of
butyrate were also less likely to have a reported diagnosis of
food allergy or
allergic rhinitis . -
pubmed
Oral administration of
SCFAs to
mice significantly reduced the severity of
allergic airway inflammation . -
pubmed
CONCLUSION : Our results suggest that strategies to increase
SCFA levels could be a new dietary preventive option for
allergic diseases in
children . -
pubmed
Frosty pod rot ( FPR ) disease on cocoa , caused by
Moniliophthora roreri , is one of the most devastating
cocoa disease in the Western Hemisphere . -
pubmed
Insulin resistance : a key therapeutic target for cardiovascular risk reduction in obese
patients ? -
pubmed
As clinical studies suggest that
insulin resistance may play a key role in the cardiovascular benefit achieved with
weight loss intervention , we will discuss our clinical perspective and provide evidence that
obese individuals with
hyperinsulinemia may derive the greatest improvement in vascular function with
weight reduction . -
pubmed
MR findings of
uterine PEComa in
patients with
tuberous sclerosis : report of two cases . -
pubmed
Today , increased attention has been focused on
PML development in
multiple sclerosis (
MS )
patients under disease - modifying therapies ( DMT ) . -
pubmed
Our study was performed in a population of 234
patients with
type 2 diabetes mellitus (
T2DM ) and 78 healthy subjects . -
pubmed
Pupose : To experimentally compare the visual acuity and the subjective perception of different types of multifocal intraocular lenses ( IOL ) using a VirtIOL device / simulator in a group of
volunteers with
artephakia . -
pubmed
MATERIAL AND METHODS : This was an experimental study involving a total of 20
volunteers with
artephakia ( 35 eyes ) . -
pubmed
Each
volunteer rated 5 types of IOLs , 4
presbyopia - correcting IOLs - WIOL - CF , Tecnis Symphony ZXR00 , Acrysof IQ PanOptix TFNT00 , M - flex 630 F , and as a reference lens , we used the monofocal IOL Acrysof SA60AT . -
pubmed
Conclusions : The
patients in the non - PPI group were observed to be associated with less risk of
MACE ,
myocardial infarction recurrence ,
stent thrombosis , target vessel revascularization ( TVR ) and
stroke . -
pubmed
Potential clinical aims in imaging
patients with
CAAs may be primary screening , severity evaluation , preoperative planning , and postoperative follow - up . -
pubmed
Rarely , IVUS may be needed in
patients with potentially serious
CAAs and has unique advantages and limitations . -
pubmed
In
adolescents or adults , intramural course of an anomalous coronary artery is the only important feature accompanied by
stenosis of potential severity and is especially relevant in patients with a high - risk status ( elite sport athletes , military recruits ) . -
pubmed
OBJECTIVE : To review the etiology and clinical manifestations of severe cutaneous adverse reactions (
SCARs ) and the demographic characteristics of
patients with
SCARs . -
pubmed
METHODS : This study is a retrospective review of electronic medical records for
patients who developed drug - induced
cutaneous reactions and were treated for initial or ongoing care at a university medical center from June 4 , 2008 , to August 10 , 2018 . -
pubmed
Most of the
patients with
SCARs were given
triamcinolone cream and
prednisone alone ( 18 [ 51.4 % ] ) ,
methylprednisolone alone ( 1 [ 2.9 % ] ) ,
methylprednisolone and
prednisone combined ( 4 [ 11.4 % ] ) ,
methylprednisolone and
prednisolone ( 1 [ 2.9 % ] ) or
prednisone and
prednisolone ( 1 [ 2.9 % ] ) . -
pubmed
Among 5028
patients with
HF and reduced ejection fraction (
HFrEF ; EF & lt;40 % ) and 1139 patients with
HF and preserved EF (
HFpEF ; EF & gt;=50 % ) , the prevalences of
type 2 diabetes mellitus were 40.2 % and 45.0 % , respectively ( P=0.003 ) . -
pubmed
Emesis castigata diringeri Gallard 2008 is a subjective junior synonym of
E. - pubmed
NK cells represent 10 - 20 % of total lymphocytes in the peripheral blood of
humans and play an essential role in clearing
infections and malignant cells . -
pubmed
Alternatively , considering our REE findings in adult 21 - OH CAH
patients , nutrition management based on 25 kcal /
body weight / day ( measured REE * activity factor 1.2 - 1.3 ) may be reasonable for current
body weight maintenance in these patients . -
pubmed
Urolithiasis in
Children . -
pubmed
Outcome in
patients with isolated regional
recurrence after primary radiotherapy for
head and neck cancer . -
pubmed
Factors prognostic for outcome were investigated in a large cohort of
HNSCC patients . -
pubmed
No - reflow phenomenon (
NRP ) is an important problem in
patients with
ST - segment elevation myocardial infarction (
STEMI ) undergoing primary percutaneous coronary intervention ( pPCI ) . -
pubmed
Consecutive
patients ( n = 137 ) with
STEMI who had undergone coronary angiography and pPCI were enrolled into the study . -
pubmed
An 18 - year - old
man showed
swelling ,
pain , and limited motion of the hand , knee , and foot joints without
X - ray abnormalities at 2 years old ( X-16 ) . -
pubmed
Morphology of the cisterna chyli in nine
dogs with
idiopathic chylothorax and in six healthy
dogs assessed by computed tomographic lymphangiography . -
pubmed
OBJECTIVE : To describe the morphology of the lymphatics in the region of the cisterna chyli in healthy
dogs and in
dogs with
idiopathic chylothorax by using computed tomographic lymphangiography . -
pubmed
ANIMALS : Nine
dogs with
idiopathic chylothorax and six healthy
dogs . -
pubmed
Data ( mean + - SD ) were compared between unaffected
dogs and
dogs with
idiopathic chylothorax . -
pubmed
RESULTS : The cisterna chyli included more branches in
dogs with
chylothorax ( 4.30 + - 1.57 ) than in unaffected
dogs ( 1.67 + - 0.56 , P = .02 ) , occupying a relative perimeter approximately double that in unaffected
dogs ( P < .001 ) . -
pubmed
CONCLUSION : The cisterna chyli of
dogs with
idiopathic chylothorax contained smaller and more numerous branches compared with that of unaffected
dogs . -
pubmed
CLINICAL SIGNIFICANCE : Altered cisterna chyli morphology may impact the surgical approach for cisterna chyli ablation in
dogs with
idiopathic chylothorax . -
pubmed
Overall , successful management of
MTC patients heavily relies on the patient 's conditions ,
tumor stage , genetic background , and the medical team 's experience . -
pubmed
Forty
patients were surgically treated for lateral
pain- ful
instability of the ankle . -
pubmed
We recruited 12 068
patients with
AF ( 6034
patients in each cohort ) . -
pubmed
The performance of
hepatitis C virus (
HCV ) antibody point - of - care tests on oral fluid or whole blood and dried blood
spot testing for
HCV serology and viral load among individuals at higher risk for
HCV in South Africa . -
pubmed
Degradation of
benzo [ a ] pyrene by halophilic bacterial
strain Staphylococcus haemoliticus strain 10SBZ1A. -
pubmed
A 62 - year - old
man developed a recurrent
keratoacanthoma within two and a half weeks after grossly and microscopically complete removal of the primary
tumor . -
pubmed
The importance of uropathogenic
Escherichia coli in causing acute and recurrent
pyelonephritis with the consequent morbidity of
chronic renal failure is well established . -
pubmed
Pyelonephritis - associated ( Pap ) pili are likely to be critical virulence factors in uropathogenic
E. - pubmed
Heel erosion and other
interdigital disorders in dairy
cows : associations with season ,
cow characteristics , disease , and production . -
pubmed
Epidemiologic associations between variables obtainable from dairy
cow records and the occurrence of
heel erosion ,
interdigital dermatitis , and
interdigital hyperplasia at claw trimmings were estimated with multivariable logistic regression analysis on data from 1170 and 542
cows in lactation 1 and lactations 2 to 9 , respectively . -
pubmed
In the 17 herds ,
heel erosion ,
interdigital dermatitis , and
hyperplasia occurred among 43.8 , 4.5 , and .9 % of
cows in lactation 1 and among 69.1 , 7.6 and 5.9 % of
cows in lactations 2 to 9 , respectively . -
pubmed
In the present study , although considerable intersubject variability was observed , several subjects exhibited deficits on the brief tone frequency difference limen test similar to that observed with
temporal lobe lesion patients , but present at both ears . -
pubmed
Suppression by
beta - carotene - rich algae
Dunaliella bardawil of the progression , but not the development , of spontaneous
mammary tumours in
SHN virgin mice . -
pubmed
A high
mammary tumour strain of
SHN virgin mice were given
vitamin A deficient AIN-76TM diet supplemented with
D. - pubmed
bardawil maintained the levels of non - tumorous
mice even after the development of
tumours . -
pubmed
bardawil can inhibit the progression of spontaneous
mammary tumours of
mice by increasing the homeostatic potential of the host animals as well as by the well - known antioxidant function of
beta - carotene in
D. - pubmed
The typical radiologic finding of a "
non - ossifying fibroma " of the distal femoral metaphysis was seen in a 17 - year - old female
patient with
pain in the distal femur . -
pubmed
Infectious crystalline keratopathy caused by
Mycobacterium fortuitum and
Pseudomonas aeruginosa . -
pubmed
We have characterized autoantibodies that are directed against this particle from two
patients with
rheumatic diseases . -
pubmed
Plasma volume expansion and PEEP in a
canine model of acute Pseudomonas
pneumonia . -
pubmed
Four groups of anesthetized , ventilated
dogs ( n = 6 in each group ) inoculated endotracheally with
Pseudomonas aeruginosa were studied over 5 h as bilateral ,
hemorrhagic pneumonia developed . -
pubmed
Cervical cultures of 2013 consecutive obstetric patients with no history of
genital herpes simplex virus infection were used to determine the frequency of asymptomatic
herpes simplex virus shedding in labor . -
pubmed
Transient problems , such as
pain or
penile edema lasting longer than 4 weeks , occur in 10 to 15 per cent of
patients , and serious complications such as
infection or
prosthesis erosion occur in 1 to 5 per cent . -
pubmed
[ Effect of the administration of killed
Lactobacillus acidophilus on the survival of suckling
mice infected with a
strain of enterotoxigenic
Escherichia coli ] . -
pubmed
The response of
canine platelets to
arachidonic acid ( AA ) stimulation was studied as a predictor of
thrombotic potential . -
pubmed
Group I ( control )
dogs whose platelets aggregated in response to AA stimulation had significantly higher 24 - hour
platelet deposition ( % IE ) on the luminal surface of implanted grafts ( p less than 0.02 ) , lower 4 - week graft patency ( p less than 0.002 ) , and higher plasma
TxB2 levels ( p less than 0.01 ) than those
dogs whose platelets did not aggregate . -
pubmed
There is evidence suggesting a correlation between
Epstein - Barr virus (
EBV ) and the high incidence of
lymphomas , and the most plausible explanation for this is the ability for
EBV to cause ongoing B cell proliferation . -
pubmed
Animals bearing
subcutaneous Lewis lung tumors ( 50 - 100 mm3 ) were treated with a single dose of
Fluosol - DA followed by 1 h of breathing
carbogen or maintenance in air . -
pubmed
A sixty - one - year - old
woman developed acquired
infundibular pulmonary stenosis eleven years after radiation therapy to the mediastinum . -
pubmed
This study was undertaken to detect diagnostic ultrastructural changes in the alveolar walls in biopsies of
patients with
primary pulmonary hypertension (
PPH ) . -
pubmed
By light microscopy 4
patients were diagnosed as having
plexogenic pulmonary arteriopathy , 2
thromboembolic arteriopathy and 2
veno - occlusive ( PVOD ) disease . -
pubmed
In 4
patients the diagnosis of
PPH was further confirmed at autopsy . -
pubmed
These consisted in marked thickening and duplication of the basement membrane of alveolar capillaries in the 4
patients with the plexogenic form of
pulmonary hypertension . -
pubmed
Patients with
PVOD instead showed uniform thickening of the basement membrane . -
pubmed
No changes were detected in the 2 biopsies of
patients with the thromboembolic form of
PPH . -
pubmed
We conclude that ultrastructural studies contribute significantly to the precise characterization of pathologic changes in the lungs of
patients with
PPH . -
pubmed
[ Cell populations of transplantable
murine tumors of various degrees of histogenesis during their proliferation in the anterior chamber ] . -
pubmed
N = 66
children ( none with an acute indication for surgery ) were observed immediately before premedication and again immediately before anaesthetization ; the
anxiety of the
children was scaled on 8 rating - scales . -
pubmed
A
foot and mouth disease syndrome in
pigs caused by an enterovirus . -
pubmed
[ Pathogenesis of
cotton - wool
spots . -
pubmed
Among the 69
Proteus mirabilis strains studied , 75 % contained Tn7 , although none of these
strains transferred
trimethoprim resistance in conjugation tests . -
pubmed
In a double - blind controlled study lasting 8 weeks , 50 anxious psychoneurotic
outpatients with a primary diagnosis of generalized
anxiety or
panic disorder were randomly assigned to
alprazolam ( n=30 ) , a new
benzodiazepine , or placebo ( n=20 ) , after a washout period of 1 week . -
pubmed
The epidemiological studies were designed to examine for associations between
human leukemia and a rural environment ,
cattle farming , veterinary activities , or
bovine leukosis . -
pubmed
The serological studies were used to test serum samples from
human cancer patients and from persons with potential occupational exposure to
BLV , among others , for evidence of
BLV antibodies . -
pubmed
[ Problems in
hypertension therapy in
patients with a constant frequency pacemaker ] . -
pubmed
Frozen and thawed prisms from three
human neocortical specimens showed a similar degree of protection from freeze - thaw
injury . -
pubmed
High dose
barbiturates were used to treat
intracranial hypertension in 15
patients with nontraumatic
brain lesions ; ( 3
hypertensive hemorrhage , 4
subarachnoid hemorrhage , 5
infarction , 2 global
anoxia -
ischemia and 2
encephalitis ) . -
pubmed
Survival of the 5
patients with persistently lowered ICP and
death of the remaining 10 may indicate an improvement in outcome attributable to the addition of high dose
barbiturates to conventional therapy in
non - traumatic brain swelling . -
pubmed
Because of the resources required for their prolonged use , randomized studied in
patients with
intracranial hypertension are required to determine the effect of
barbiturates on outcome . -
pubmed
[ Changes in the mechanisms of respiration and cardiovascular function in bronchoconstriction caused by cigarette smoke and
anaphylaxis in
rabbits ] . -
pubmed
Human in vivo evidence for trigeminovascular activation in
cluster headache . -
pubmed
In this study
patients with
episodic cluster headache fulfilling the criteria of the International
Headache Society were examined during an acute spontaneous attack of
headache to determine the local cranial release of neuropeptides . -
pubmed
These data demonstrate for the first time in vivo
human evidence for activation of the trigeminovascular system and the cranial parasympathetic nervous system in an acute attack of
cluster headache . -
pubmed
OBJECTIVE : The aim of the present study was to determine the accuracy of clinical diagnoses of
dementia in a large group of
patients evaluated in a multicenter , university - based ,
Alzheimer ' s disease diagnostic and treatment program . -
pubmed
RESULTS : When diagnoses of probable
Alzheimer ' s disease , possible
Alzheimer ' s disease , and
Alzheimer ' s disease plus another condition were combined , 163 ( 83 % ) of the
patients were clinically regarded as likely to have had
Alzheimer ' s disease . -
pubmed
Of those
patients , 134 ( 82 % ) were found to have neuropathological changes diagnostic of
Alzheimer ' s disease or
Alzheimer ' s disease plus another condition . -
pubmed
A total of 116
patients were diagnosed as having probable
Alzheimer ' s disease ; 100 ( 86 % ) of those were found to have pathological diagnoses of
Alzheimer ' s disease or
Alzheimer ' s disease plus another condition . -
pubmed
Cerebral infarcts were found in 17 % of the
patients clinically diagnosed with probable
Alzheimer ' s disease . -
pubmed
Lewy bodies with variable
Alzheimer ' s disease - type pathological changes were found in 7 % of the
patients with clinical diagnoses of probable
Alzheimer ' s disease . -
pubmed
Conversely , significant
Alzheimer ' s disease - type pathological changes were found in 55 % of the
patients clinically diagnosed as having
vascular dementia . -
pubmed
CONCLUSIONS : Clinicians accurately predict
Alzheimer ' s disease - type neuropathological findings in a high proportion of cases of
dementia but may not predict cerebrovascular pathology and
Lewy bodies in some
patients with apparent clinical
Alzheimer ' s disease and may often fail to predict
Alzheimer ' s disease - type pathological findings in
patients with apparent
vascular dementia . -
pubmed
The influence of
zinc supplementation on
ethanol - induced
embryopathy was studied by the simultaneous administration of
ethanol and
zinc to pregnant SD
rats from gestational day 6 through 12 . -
pubmed
Catheter obstruction occurred in one
patient ( case 2 ) . -
pubmed
Inhalation of vapor from
black pepper extract reduces smoking
withdrawal symptoms . -
pubmed
We have studied
patients with
supraventricular arrhythmias , especially those suffering from the
Wolff - Parkinson - White ( WPW ) syndrome . -
pubmed
Magnetocardiographic localization of the preexcitation site was performed in 26
WPW patients , with an average accuracy of 2 + /- 1 cm in comparison to the results obtained by invasive catheter mapping . -
pubmed
In addition , the level of conduction block was successfully determined in six
patients with third - degree
congenital atrioventricular block . -
pubmed
The protective effect of
folic acid supplementation has been demonstrated in
patients at risk of
neural tube defects by a large , randomized double - blind study . -
pubmed
Moreover , the plasma level of
conjugated dopamine in
patients with essential
hypertension was higher than that in control subjects , and being highest in
patients with
renal hypertension . -
pubmed
The prevalence and specificity of these antibodies was studied in a French series of 285
patients with
PBC and 497 control
individuals affected with other liver or
autoimmune diseases . -
pubmed
At all ratios tested , AMs from
patients with
FL did not suppress the lymphoproliferation but instead had an enhancing effect . -
pubmed
In conclusion , a defect in the ability of alveolar macrophages to suppress the proliferation of lymphocytes in the lung of
patients with
farmer 's lung is a major factor accounting for the development of the observed
lymphocytic alveolitis . -
pubmed
VLPs of
human papillomavirus (
HPV ) are therefore the most promising vaccine candidate to prevent
infections with
HPVs associated with
cervical cancer , the most frequent
carcinoma in women worldwide . -
pubmed
METHODS : A total of 32
patients who had undergone resection for colorectal
carcinoma were followed for a median period of 24 months ( range , 6 - 36 months ) . -
pubmed
Twenty - one
patients ( Group 1 ) had no signs of
recurrence , whereas the remaining 11 ( Group 2 ) developed hepatic ( n = 7 ) or pulmonary ( n = 4 )
metastases . -
pubmed
The risk of
perinatal transmission of hepatitis C virus (
HCV ) from a cohort of 95
human immunodeficiency virus ( HIV )- negative intravenous drug users ( IVDU ) is described , 89 of whom were positive for antibodies to
HCV ( anti -
HCV ) . -
pubmed
Infection , defined as the presence of
HCV RNA in a serum sample collected from an infant at any time during follow - up , was detected in six of 63 ( 9.5 % ) infants born to
HCV antibody - positive viraemic mothers . -
pubmed
Two of the six
HCV - infected infants became
HCV RNA negative during follow - up by 27 and 29 months . -
pubmed
No difference was found between mothers who transmitted
HCV to their infants and those who did not for
HCV genotype , duration of drug use , duration of
methadone use ,
methadone dose , history of
alcohol abuse , past
hepatitis B virus ( HBV ) infection , mode of delivery , maternal and gestational age ,
birth weight and incidence of breast - feeding . -
pubmed
Mothers who transmitted
HCV to their infants had a longer duration between membrane
rupture and delivery than the mothers who did not transmit ( P = 0.03 ) . -
pubmed
pylori in a prospectively investigated population of
patients with corpus - predominant
atrophic gastritis . -
pubmed
PATIENTS AND METHODS : A consecutive series of 67 newly diagnosed cases of
atrophic body gastritis was derived from a screening of 326
patients with unexplained
anemia or
dyspepsia . -
pubmed
In all 67
patients , H.
pylori infection was evaluated independently by histological assay and urease test . -
pubmed
pylori infection , a potential cause of
oxyntic gland atrophy , is found in one - fourth of
patients with newly diagnosed
atrophic body gastritis . -
pubmed
Anaerobic degradation of
alpha - resorcylate (
3,5 - dihydroxybenzoate ) was studied with the denitrifying
strain AR-1 , which was assigned to the described species
Thauera aromatica . -
pubmed
We studied clinical aspects of attention in three groups :
children with
developmental right - hemisphere syndrome and
attention - deficit hyperactivity disorder (
ADHD ) ,
children with
ADHD only , and normal controls . -
pubmed
A high proportion of
patients with
hyperemesis gravidarum , about one - third to two - thirds in different series , have evidence of increased thyroid function . -
pubmed
Only a small proportion of these
patients have clinical
hyperthyroidism , termed
gestational thyrotoxicosis . -
pubmed
Independent risk factor for long - term prognosis after
myocardial infarction even in nondiabetic
patients . -
pubmed
OBJECTIVE : To investigate whether a relationship exists between admission plasma
glucose level and long - term outcome in nondiabetic
patients after an
acute myocardial infarction . -
pubmed
RESEARCH DESIGN AND METHODS : This was a retrospective study with prospective follow - up of 197 consecutive nondiabetic
patients with
acute myocardial infarction followed for 1.5 - 2.5 years at the Department of Cardiology at Karolinska Hospital . -
pubmed
RESULTS : The mean admission plasma
glucose level was 8.15 + /- 3.0 mmol / l. During follow - up , 60 ( 30 % )
patients died , 20 ( 10 % ) were rehospitalized for
heart failure , 12 ( 6 % ) were rehospitalized for nonfatal
reinfarction , and 79 ( 40 % ) had at least one of these events . -
pubmed
CONCLUSIONS : Admission plasma
glucose level in nondiabetic
patients with
acute myocardial infarction seems to be an independent predictor of long - term outcome . -
pubmed
A 64 - year - old
man with
Cushing ' s syndrome and a
pancreatic mass . -
pubmed
Since plasmapheresis can reverse clinical symptoms , it early recognition and the measurement of serum viscosity is essential in
patients suffering from diseases that may lead to this syndrome , and who develop
psychiatric symptoms . -
pubmed
Pericarditis after allogeneic peripheral blood stem cell transplantation caused by
Legionella pneumophila ( non - serogroup 1 ) . -
pubmed
A case of
Legionella pericarditis caused by a
Legionella pneumophila isolate other than serogroup 1 is reported in a 59 - year - old
man after allogeneic peripheral blood stem cell transplantation . -
pubmed
The
patient 's clinical condition improved dramatically after treatment with
clarithromycin and an echocardiography revealed the total disappearance of the
pericardial effusion . -
pubmed
We studied the clinicopathologic features of 36
patients with concurrent
angiomyolipoma and
renal - cell neoplasia from the consultation and surgical pathology files of nine institutions . -
pubmed
Twenty - five sporadic cases of
patients with
angiomyolipoma and
renal - cell neoplasia and 11 cases of
patients with
tuberous sclerosis , as defined by Gomez ' criteria , had mean ages of 59 and 53 years , respectively , and female - male ratios of 2:1 and 5:1 , respectively . -
pubmed
The mean size of the
angiomyolipomas was 1 cm in the sporadic cases and 3 cm in those
patients with
tuberous sclerosis ( medians : 0.5 and 3 cm , respectively , P = .002 ) . -
pubmed
In
patients with
tuberous sclerosis , 27 % of
renal - cell neoplasms were
oncocytomas , compared with 8 % in sporadic cases ( P = .15 ) . -
pubmed
Also , the results suggested that betel quid chewers may harbor higher levels of
infection with
A. - pubmed
In conclusion , betel quid chewing was associated with a higher prevalence of
bleeding on probing where higher clinical levels of disease existed , and with a likelihood of
subgingival infection with
A. - pubmed
A case report of acute invasive
fungal rhinosinusitis in 28 year old
woman with
acute myeloid leukemia is described in this paper . -
pubmed
METHODS : Ninety - eight
patients participated in a prospective , Institutional Review Board - approved , relational database study in the
Hemangioma and Vascular Birthmark Center at the Children 's Hospital of Buffalo ( Buffalo , NY ) from July 1998 to April 2000 . -
pubmed
This included 68
patients with
hemangiomas and 30 with
vascular malformations . -
pubmed
RESULTS : Fifty lesions were identified in 49
patients ( 38 portal vein and 12
hepatic vein - cava stenoses ) . -
pubmed
Recurrence occurred in 9
patients : all were amenable to stenting . -
pubmed
Nine
patients ( 24 % ) eventually died of
sepsis ( 4 ) and surgical
deaths at shunt or retransplant ( 5 ) . -
pubmed
All
patients were diagnosed by venogram and managed by balloon dilatation alone ( n = 6 ) or stented ( n = 4 ) , with an 80 % ( 10/12 ) success , with two late
recurrences amenable to repeat angioplasty or stenting . -
pubmed
Patients with
anterior cruciate ligament instability resulting from
incomplete tears or elongation in continuity without ligament detachment historically have been treated conservatively or by graft replacement . -
pubmed
Determination of serum
fibrosis indexes in
patients with
chronic hepatitis and its significance . -
pubmed
RESULTS : Among 2600
chronic hepatitis patients , every fibrotic index had a significant correlation with the
inflammation grade ,
fibrosis staging and the degree of
chronic hepatitis ( P & lt ; 0.01 ) . -
pubmed
BACKGROUND : Renal transplant
recipients are at increased risk of premature
cardiovascular disease . -
pubmed
Worth noting is the fact that it can occur in a
child with
height deficiency . -
pubmed
A total of 189 children with bacterial complications of the acute
respiratory viral infection (
ARVI)--primarily with
pneumonia and
bronchitis -- were dynamically examined for typical and atypical pneumotropic causative agents of the
infection process (
Mycoplasma pneumoniae , Chlamydia spp . -
pubmed
A high frequency rate of the associative
infection involving
mycoplasmas and
pneumocysts was registered ( 45 - 50 % ) ; it was lower in the cases involving Chlamydias , hemophilic bacteria ,
pneumococcus , and
cytomegalovirus -- up to 25 - 30 % . -
pubmed
Pathologic study of
intravascular coagulation following incompatible blood transfusion in
dogs . -
pubmed
METHODS : Forty 12 week - old female SD
rats were randomly assigned to four groups : ( 1 ) sham operated ; ( 2 ) ovariectomized ; ( 3 ) ovariectomized and treated with
estradiol ; ( 4 ) ovariectomized and received
genistein , 45 mg / kg
body weight per day . -
pubmed
The clinical features of 15
patients with breast
metastases from
extramammary malignancies , excluding
lymphoma , between 1982 and 2001 were retrospectively reviewed . -
pubmed
Breast
metastases were associated with disseminated metastatic
disease in 14 of the 15
patients . -
pubmed
DSM - IV mental disorders and neurological complications in children and adolescents with
human immunodeficiency virus type 1 infection (
HIV-1 ) . -
pubmed
METHODS : - 17
HIV - infected children presenting with
psychiatric problems were included . -
pubmed
We measured tissue
oxygen saturation ( StO2 ) changes during a post - occlusive reactive
hyperemia ( PORH ) test on lower extremities of
peripheral vascular disease (
PVD )
patients and healthy controls . -
pubmed
A 68 year old
man presented with
urethritis and a
purulent discharge , carrying the tentative diagnosis of
gonorrhea . -
pubmed
Microbiological investigation revealed
Pseudomonas aeruginosa , a relatively frequent Gram - negative bacteria in hospitals , which can cause several
nosocomial diseases such as
pneumonia ,
wound infections and
urogenital infections . -
pubmed
Pseudomonas aeruginosa - induced
urogenital infections in ambulatory patients are extremely rare and usually not associated with a
gonorrhea - like discharge . -
pubmed
BACKGROUND AND AIMS : Ileal pouch - anal anastomosis ( IPAA ) improves quality of life ( QOL ) for
ulcerative colitis patients who require surgery . -
pubmed
METHODS We enrolled 124
patients : normal pouches ( N = 26 ) ,
CD of the pouch ( N = 23 ) ,
pouchitis ( N = 22 ) ,
cuffitis ( N = 21 ) , and
IPS ( N = 32 ) . -
pubmed
Synovial sarcoma (
SS ) is one of common
malignant soft - tissue tumors and is encountered most commonly in
children and young adults . -
pubmed
Patients with
COM stones were significantly older than patients with COD stones ( P & lt ; 0.002 ) . -
pubmed
We performed 114 consecutive primary total hip arthroplasties with a cementless expansion acetabular component in 101
patients for advanced
osteonecrosis of the femoral head . -
pubmed
Mononuclear cell populations in the lungs of calves infected with
Dictyocaulus viviparus were studied during primary
infection and reinfection in order to identify cells involved in development of protective immunity to
parasitic bronchitis . -
pubmed
In all , 1,465 FSFTs in 8,057
trauma registry
patients ( age 39 + /- 19.5 years ; Injury Severity Score [ ISS ] 23.5 + /- 14.9 ; 17.3 % mortality ) were treated initially ( & lt;24 hour ) by EF , nail , or plate in 47.0 % , 41.1 % , and 11.9 % , respectively . -
pubmed
We exposed 69 wild - type and 67 mutant
mice to two
hyperoxic tests ( 12 - min air followed by 3 - min 100 %
O2 ) 2 days after birth . -
pubmed
METHODS : Teacher and parent forms of the
Autism Spectrum Screening Questionnaire ( ASSQ ) were used in the " Bergen Child Study " , a total population study of 9430
children aged 7 - 9 years . -
pubmed
CONCLUSION :
89SrCl2 is effective for palliation of
bone pain in
patients with disseminated
bone metastases . -
pubmed
In addition to managing
pain ,
89SrCl2 can improve immunity and the quality of life for most
patients . -
pubmed
We report 6
patients with
adenolipomas of the head and neck region : 3 in the parathyroid , 2 in the thyroid , and 1 in the parotid gland . -
pubmed
The
patients with parathyroid
adenolipomas manifested
signs and symptoms of
hyperparathyroidism , whereas the others complained of a mass in the neck . -
pubmed
Carnitine esters prevent oxidative stress damage and energy depletion following transient
forebrain ischaemia in the
rat hippocampus . -
pubmed
Rats in the seventh group were subjected to sham - operated
ischaemia and injected with normal saline for 7 successive days . -
pubmed
There were 27
patients with acute and 2 with chronic
type A aortic dissection . -
pubmed
One
patient with acute dissection and 1 with chronic
aneurysm died during the early postoperative course . -
pubmed
Two
patients with severe calcification of the aortic valve had
strokes . -
pubmed
There were no
strokes in the dissection group , although there were preoperative signs of
cerebral malperfusion in 4
patients . -
pubmed
After a large screening on
sourdough lactic acid bacteria , exopolysaccharide ( EPS)-forming
strains of
Weissella cibaria ,
Lactobacillus plantarum , and
Pediococcus pentosaceus were selected . -
pubmed
Compared to the sourdough started with an EPS - negative
strain , the sourdough started with
W. - pubmed
METHODS : Among CSS
patients treated during the past 10 years at 2 French university hospitals , we have identified and described 2 cases revealed by tamponade with pericardial biopsy - proven
granulomatous vasculitis . -
pubmed
RESULTS : The first case report describes a 66 - year - old
man who had an isolated
cardiac tamponade with both inflammatory
syndrome and
eosinophilia . -
pubmed
The second case report describes a 46 - year - old
woman whose
CSS presented with
tamponade and associated central nervous system and myocardial involvement . -
pubmed
Gefitinib in
patients with progressive
high - grade gliomas : a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro - Oncologia ( GICNO ) . -
pubmed
To investigate the role of
gefitinib in
patients with high - grade
gliomas (
HGGs ) , a phase II trial ( 1839IL/0116 ) was conducted in
patients with disease
recurrence following surgery plus radiotherapy and first - line chemotherapy . -
pubmed
Adult
patients with histologically confirmed recurrent
HGGs following surgery , radiotherapy and first - line chemotherapy , were considered eligible . -
pubmed
Patients were treated with
gefitinib ( 250 mg day(-1 ) ) continuously until
disease progression . -
pubmed
Sixteen
patients had
glioblastoma , three
patients had
anaplastic oligodendrogliomas and nine
patients had
anaplastic astrocytoma . -
pubmed
Gefitinib showed limited activity in
patients affected by
HGGs . -
pubmed
Tissue from six
osteoarthritic patients was obtained during revision arthroplasty . -
pubmed
Since that time , there have been considerable advances in imaging techniques as well as the advent of devices to help in the management of
acute stroke patients . -
pubmed
Lactococcus garvieae is considered an emergent pathogen in aquaculture and it is also associated with
mastitis in domestic animals as well as
human endocarditis and
septicaemia . -
pubmed
2.4 % ) were identified which could not be recovered from
rainbow trout following
infection . -
pubmed
During CV and VV(O ) , normal and injured
mice showed regional
lung collapse with increased airway pressures and poor oxygenation . -
pubmed
Stroke ,
multiple sclerosis and
Parkinson ' s disease patients also completed the Short Form 36 ( SF-36 ) Health Survey , the
Multiple Sclerosis Quality of Life 54 questionnaire ( MSQoL-54 ) and the
Parkinson ' s Disease Questionnaire ( PDQ-39 ) respectively . -
pubmed
Stroke patients demonstrated statistically significant improvements in the Nottingham Extended Activities of Daily living Index ( mean change 3.4 , P<0.001 ) and the SF-36 mental health subsection ( mean change 7.8 , P<0.001 ) . -
pubmed
Vaccinia virus (
VV ) is considered to cause
lytic infection of most cells , with lysis being regarded equivalent to
necrosis . -
pubmed
Gentamicin increases
nitric oxide production and induces
hearing loss in
guinea pigs . -
pubmed
METHODS : A single dose of
gentamicin ( 10 mg / kg
body weight ) was injected intratympanally into male
guinea pigs and the auditory brainstem responses were recorded before treatment and 1 , 2 , and 7 days after application . -
pubmed
Comparison of magnetic resonance imaging versus Doppler echocardiography for the evaluation of left ventricular diastolic function in
patients with
cardiac amyloidosis . -
pubmed
To assess the role of magnetic resonance imaging ( MRI ) in the assessment of diastolic function , diastolic mitral inflow parameters using MRI and transthoracic Doppler echocardiography ( echocardiography ) were compared in
patients with
cardiac amyloidosis . -
pubmed
Thirty - eight
patients ( age 60 + /- 12 years ; 32 %
women ) in
sinus rhythm with
cardiac amyloidosis ( biopsy - proven systemic
amyloidosis and positive echocardiographic and contrast - enhanced cardiac MRI findings ) were evaluated . -
pubmed
In conclusion , mitral inflow peak velocities , deceleration times , and E / A ratios detected using phase - contrast MRI in
patients with
cardiac amyloidosis showed moderately good correlation with echocardiography and identified most patients with restrictive echocardiographic patterns . -
pubmed
This demonstration of an X chromosome gene as a
disease susceptibility factor in
human SLE raises the possibility that the gender difference in
SLE may in part be attributed to sex chromosome genes . -
pubmed
METHODS : Lifetime
ethanol consumption was assessed at baseline ( 1994 - 1995 ) in a prospective , population - based study in central Spain of 3285 elderly
participants , 76 of whom developed incident
ET by follow - up ( 1997 - 1998 ) . -
pubmed
Ethanol is often used for symptomatic relief ; studies should explore whether higher consumption levels are a continued source of underlying
cerebellar neurotoxicity in
patients who already manifest this disease . -
pubmed
Nitric oxide as a partner of reactive
oxygen species participates in
disease resistance to nectrotophic pathogen
Botryis cinerea in
Nicotiana benthamiana . -
pubmed
Two
subjects with adequate baseline
iron stores developed
erythrocytosis followed by neocytolysis . -
pubmed
After giving informed consent ,
patients with lower - limb closed
fractures rated their
pain on a 10 - cm visual analog scale ( VAS ) . -
pubmed
Patient evaluations of
pain intensity were recorded throughout two periods : twenty - four hours pre - surgically and twenty - four hours postsurgical . -
pubmed
BACKGROUND :
depression has a significant prevalence in
patients following a
stroke . -
pubmed
In phase 2 , Of the 18
patients screened , 10 patients ( 56 % ) scored 5 or above , which according to the scoring system of the PHQ-9 is indicative of
depression . -
pubmed
If the
neurotoxicity of anaesthetics in
human remains debatable , perioperative period is certainly a high - risk factor for
cognitive impairment , especially in elderly population . -
pubmed
Accordingly ,
TCF1 - deficient mice are hyperresponsive to experimental
autoimmune encephalomyelitis . -
pubmed
In this study , we investigated retrospectively the efficacy of
rufinamide (
RUF ) in five
infants with
MMPEI , by examining
seizure type and frequency , EEG features and antiepileptic drug use . -
pubmed
The data demonstrate that two of the five
patients showed good efficacy and tolerability for RUF with a & gt ; 50 % reduction in
seizure frequency . -
pubmed
The potential for metastasis makes recognition of
CHRCC cells in cytologic preparations important for
patient surveillance , management , and treatment . -
pubmed
Relationship between three - year survival and functional outcome at discharge from acute - care hospitals in each subtype of first - ever
ischemic stroke patients . -
pubmed
BACKGROUND : We studied the relationship between survival prognosis and the functional outcome at discharge from acute - care hospitals in each subtype of
ischemic stroke patients . -
pubmed
METHODS : A total of 853 consecutive
patients with first - ever
ischemic stroke , recruited from December 1999 to November 2002 , were followed for 725.8 + - 430.0 days . -
pubmed
RESULTS : The respective mortality of the groups with mRS scores of 0 - 2 , 3 , 4 , and 5 were 13.1 % , 25.0 % , 47.2 % ( p<0.05 ) , and 74.0 % ( p<0.05 ) in
cardioembolic infarction (
CEI )
patients ; 11.3 % , 6.9 % , 5.6 % , and 46.7 % ( p<0.05 ) in
atherothrombotic infarction (
ATI )
patients ; 8.5 % , 5.6 % , 11.1 % , and 0 % ( no patient ) in
lacunar infarction (
LACI )
patients ; and 2.6 % , 3.0 % , 23.3 % ( p<0.05 ) , and 28.9 % ( p<0.05 ) in
infarction of unknown cause ( IUC ) patients . -
pubmed
Multi - variate analysis showed that the mRS score was a significant predictive factor for
death in CEI
patients , and tended to be a predictive factor for
death in ATI
patients , or
IUC patients . -
pubmed
Immunohistochemical characterization of
endometriosis - associated smooth muscle cells in
human peritoneal
endometriotic lesions . -
pubmed
METHODS : We obtained biopsies from peritoneal
endometriotic lesions ( n = 60 ) and peritoneal sites distant from the
endometriotic lesion ( n = 60 ) , as well as healthy peritoneum from
patients without
endometriosis ( control tissue , n = 10 ) . -
pubmed
These controls were hysterectomy specimens from
patients without
endometriosis or
adenomyosis . -
pubmed
PURPOSE : To observe the disc - condyle relationship ,
joint effusion , and
osseous abnormalities of the condyle before and after prosthetic rehabilitation in 8 edentulous
patients with asymptomatic of bilateral
temporomandibular joints (
TMJs ) . -
pubmed
RESULTS : Before prosthetic rehabilitation , 10 joint disc displacements were found in 62.5 % of 16 TMJs of 8 edentulous
patients , including 7 medial disc displacement , 2 lateral disc displacement and
anterior disc displacement ( 6.25 % ) ; 7 TMJs had
effusion 4 had
condylar abnormalities . -
pubmed
After prosthetic rehabilitation , 10 disc displacements were found in 16 TMJs of 8 edentulous
patients , including 7 medial disc displacement , 2 lateral disc displacement , and 1
anterior disc displacement ; 7
TMJs effusion . -
pubmed
CONCLUSIONS : Long - time
tooth loss may lead to internal derangement of TMJ in edentulous
patients . -
pubmed
In short term after prosthetic rehabilitation with complete denture , there is no distinct change in disc - condylar relationship ,
joint effusion , and
condylar abnormalities in edentulous
patients . -
pubmed
Because micronutrients in
human diets ultimately come from plant sources ,
malnutrition of essential minerals is a significant public health concern . -
pubmed
METHODS : : Out of consecutive 203
patients with
descending thoracic aortic aneurysm , 89 ( 43.8 % ) received endovascular treatment [ mean age , 68 + - 8 years ; range , 29 - 82 ; male , 79 ( 88.7 % ) ; female , 10 ( 11.3 % ) ] without using angiography during the endovascular procedure . -
pubmed
Conversion to open surgery was necessary in one
patient ( 1.1 % ) because of
aortic dissection . -
pubmed
One
patient developed
paraplegia ( 1.1 % ) . -
pubmed
Early
endoleak was observed in eight
patients ( 8.9 % ) and 4 ( 4.5 % ) required additional procedures ( proximal or distal extensions ) . -
pubmed
However ,
NO production is reduced in
CKD patients , partially due to decreased endothelial
NO production . -
pubmed
Potential roles for
vitamins E and C in combination in modulating exhaustive swimming and high altitude - associated
lung injury in
rats . -
pubmed
Hypoxia impedes hypertrophic chondrogenesis of
human multipotent stromal cells . -
pubmed
Significance of
hepatic lymph node metastasis in
patients with unresectable synchronous liver
metastasis of
colorectal cancer . -
pubmed
To establish a new therapeutic strategy for initially unresectable liver
metastasis of
colorectal cancer ,
HLNs should be examined histologically in
patients undergoing resection of
hepatic lesions when they are rendered resectable by effective chemotherapy . -
pubmed
Effects of soy on metabolic biomarkers of
cardiovascular disease in elderly
women with
metabolic syndrome . -
pubmed
Participants were 75
women , ages 60 - 70 years , who were diagnosed with
MetS. -
pubmed
Gender - dependence of bone structure and properties in adult
osteogenesis imperfecta murine model . -
pubmed
Though the oim
mouse model has been the most widely studied of the
OI models , it has only recently been suggested to exhibit gender - dependent differences in bone mineralization . -
pubmed
This study provides evidence of the importance of gender in the evaluation and interpretation of potential therapeutic strategies when using
mouse models of
OI . -
pubmed
Immunophenotypic characterization and quantification of neoplastic bone marrow plasma cells by multiparametric flow cytometry and its clinical significance in Korean
myeloma patients . -
pubmed
We analyzed the MFC data of the bone marrow aspirates of 76
patients with
PCM and 33
patients with
reactive plasmacytosis . -
pubmed
The plasma cells of
patients with
reactive plasmacytosis demonstrated normal immunophenotypic patterns . -
pubmed
PURPOSE OF REVIEW : To provide an overview on the available clinical and pathological factors in high - risk
nonmuscle invasive bladder cancer (
NMIBC )
patients that help to approximate the risk of progression to muscle invasion and identify ' the '
patients requiring timely cystectomy . -
pubmed
RECENT FINDINGS :
Carcinoma in situ within the prostatic urethra of
NMIBC patients impacts on
patient 's outcome . -
pubmed
Recent findings from
patients undergoing radical cystectomy including super - extended lymphadenectomy for clinically
NMIBC confirm the substantial rate ( 25 % ) of
tumor understaging . -
pubmed
The fact that almost 10 % were found to harbor lymph node
metastases underlines the necessity to perform a meticulous lymphadenectomy in
NMIBC patients undergoing radical cystectomy . -
pubmed
Nevertheless ,
tumor understaging remains an issue of concern and warrants the value of a second transurethral resection in high - risk
NMIBC patients . -
pubmed
There is a persisting lack of rigid therapeutic recommendations in
patients with high - risk
NMIBC . -
pubmed
However , irrespective of initial treatment strategy , there is a subgroup of high - risk
NMIBC patients with progressive disease , leading almost inevitably to
death . -
pubmed
Role of RNA structure motifs in IRES - dependent translation initiation of the
coxsackievirus B3 : new insights for developing live - attenuated
strains for vaccines and gene therapy . -
pubmed
Translation initiation of the
coxsackievirus B3 (
CVB3 ) , a causative agent of
viral myocarditis , has been shown to be mediated by a highly ordered structure of the 5 ' untranslated region ( 5'UTR ) , which harbors an IRES . -
pubmed
Since translation initiation is the first intracellular step during the
CVB3 infection cycle , the IRES region provides an ideal target for antiviral therapies . -
pubmed
Phytochemical screening and
cytotoxicity studies of
Chrysophyllum pruniforme Pierre ex Engl . -
pubmed
Legumes and whole grains can modulate risk markers associated with
cardiometabolic diseases , but their possible additive / synergistic actions are unknown . -
pubmed
DESIGN AND METHODS : Sixteen
subjects with
traumatic brain injury ( five
males and 11
females ; aged 22 - 34 years ) participated in the experiment . -
pubmed
This sensor can potentially be used clinically as a subcutaneously implanted continuous monitoring device in
diabetic patients . -
pubmed
In vitro quantitative analysis , using
strains isolated from
wounds , showed that NxtSc inhibited biofilm development by
Staphylococcus aureus ,
Staphylococcus epidermidis ,
Pseudomonas aeruginosa ,
Acinetobacter baumannii , and
Klebsiella pneumoniae by inhibiting bacterial growth . -
pubmed
Markers of endothelial cell dysfunction are increased in
human omental adipose tissue from women with pre - existing maternal
obesity and
gestational diabetes . -
pubmed
OBJECTIVE : To determine the effect of maternal
obesity and
gestational diabetes mellitus (
GDM ) on the expression and release of genes involved in endothelial cell dysfunction in
human placenta and omental adipose tissue . -
pubmed
MATERIALS / METHODS :
Human placenta and omental adipose tissue were obtained from non - obese and obese normal
glucose tolerant ( NGT )
women and
women with
GDM at the time of Caesarean section . -
pubmed
Alveolar macrophages are considered the first cells infected by
Mtb during
respiratory infection . -
pubmed
The definition of the cellular and molecular mechanisms involved in the immune response to
Mtb can be helpful in developing new preventive strategies to avoid
infection relapse , particularly in
patients treated with biological agents . -
pubmed
METHODS : We treated 10 eyes of nine
patients with
PED (
Stevens - Johnson syndrome : three eyes ;
thermal / chemical injury : five eyes ;
ocular cicatricial pemphigoid : two eyes ) with COMET at Kyoto Prefectural University of Medicine , Kyoto , Japan from 2002 to 2008 . -
pubmed
CONCLUSION : COMET enabled complete epithelialization of PED and stabilization of the ocular surface in
patients with severe
ocular surface disease , thus preventing end - stage
cicatrization and
vision loss at a later stage . -
pubmed
CONCLUSIONS : PMRT is indicated in
patients who are deemed to have a high risk of loco - regional
recurrence . -
pubmed
Resting - state studies conducted with
stroke patients are scarce . -
pubmed
Eleven
patients ( eight male and three female ; age range : 48 - 72 ) with right cortical and subcortical
ischemic infarctions and 17 controls ( eleven
males and six
females ; age range : 57 - 69 ) were assessed by neurological and neuropsychological examinations and scanned with resting - state functional magnetic ressonance imaging . -
pubmed
METHODS : Eighty - four
patients with
bipolar disorder were evaluated . -
pubmed
Both entities normally occur without adequate
trauma and predominantly in elderly
patients . -
pubmed
Herbal medicines and food supplements containing PAs are also recognized as a significant cause of
human poisoning and it is desirable that such medications are identified and subjected to strict regulation . -
pubmed
Arnebin-1 , a
naphthoquinone derivative , plays a crucial role in the
wound healing properties of
Zicao ( a traditional
wound healing herbal medicine ) . -
pubmed
Therefore , the findings of the present study indicate that
arnebin-1 promotes the
wound healing process in
diabetic rats by eliciting a pro - angiogenic response . -
pubmed
CHARACTERISTICS AND OUTCOMES OF
PATIENTS WITH
CHRONIC MYELOGENOUS LEUKEMIA IN BLAST CRISIS . -
pubmed
METHODS : Clinical records of 20
patients with
CML who transformed to
BC in two years between January 2012 and December 2013 were reviewed . -
pubmed
RESULTS : Out of total 240
patients , 20 ( 8.3 % ) transformed to
blast crisis ; among them 75 % were males and 25 % females . -
pubmed
Eight
patients ( 40 % ) were transformed to
acute myeloid leukaemia (
AML ) and 12 ( 60 % ) had
acute lymphoblastic leukaemia (
ALL ) . -
pubmed
These
patients were treated with standard
AML /
ALL type induction chemotherapy except one who died early . -
pubmed
Influence of
Toxoplasma gondii Infection on Male Fertility : A Pilot Study on Immunocompetent
Human Volunteers . -
pubmed
BACKGROUND : This study was conducted to investigate the influence of
Toxoplasma gondii infection on spermatic and hormonal parameters in a pilot sample of immunocompetent
human male subjects . -
pubmed
Here we identify cell types positive for
rubella virus (
RV ) in
CRS infants . -
pubmed
Participants were 11 clinically diagnosed
PD patients and 10 age and gender matched healthy controls ( HCs ) . -
pubmed
METHODS :
Pigs with ischemic
BBS were endoscopically treated either with BDBS or CSEMS . -
pubmed
Samples were harvested from
pigs with intact BD ( n = 5 ) , untreated
BBS ( n = 5 ) , and after six months of therapy with BDBS ( n = 4 ) or CSEMS ( n = 5 ) with subsequent histologic analysis . -
pubmed
Alteration of
Human Papillomavirus Type 16 Genetic and Epigenetic Profiles in
Cervical Cancer Patients Is Indicative of Poor Disease Prognosis : A Cohort Analysis . -
pubmed
OBJECTIVE : Aim of this study was to assess the changes in genetic and epigenetic profiles of
human papillomavirus type 16 (
HPV16 ) , if any , in primary
cervical cancer ( CaCx ) and corresponding plasma before and after therapy for possible prognostic evaluation . -
pubmed
RESULTS : Presence of
HPV16 in the
patients ' plasma before / after therapy was significantly ( P = 0.03 ) associated with higher viral load in the primary
tumor site . -
pubmed
Whereas in the posttherapy swabs , integrated ( 22 of 29 ) or mixed ( 7 of 29 ) form of
HPV16 prevailed with hypomethylation of the enhancer ( 6 of 29 , Z = 2.0 , P & lt ; 0.05 ) and late promoter ( 18 of 29 , Z = 4.4 , P & lt ; 0.01 ) compared with the corresponding primary
tumors . -
pubmed
The patients having high
HPV16 copy number in pretherapy and posttherapy cervical
lesions and hypomethylation of early promoter / late promoter in the corresponding plasma showed increased
disease recurrence with distant
metastases . -
pubmed
CONCLUSIONS : The genetic - epigenetic profile of
HPV16 in pretherapy / posttherapy CaCx samples showed significant association with
disease prognosis . -
pubmed
Among
patients with grade 0
adhesions , 34 ( 13.7 % ) had no striae , while 79 ( 31.9 % ) had mild - to - severe striae ( p & lt ; 0.001 ; sensitivity 55 % ; specificity 67 % ; positive predictive value 69 % ; negative predictive value 52 % ) . -
pubmed
Among
women with grade 1 - 2
adhesions , 48 ( 19.4 % ) had no striae , while 58 ( 23.4 % ) had mild - to - severe striae . -
pubmed
We propose the following practical considerations to preserve RKF , especially in newly transitioned ( incident ) hemodialysis
patients : ( 1 ) periodic monitoring of RKF in hemodialysis
patients through urine volume and including residual
urea clearance with dialysis adequacy and outcome markers such as
anemia , fluid gains , minerals and
electrolytes , nutritional , status and quality of life ; ( 2 ) avoidance of
nephrotoxic agents such as radiocontrast dye , nonsteroidal anti - inflammatory drugs , and
aminoglycosides ; ( 3 ) more rigorous
hypertension control and minimizing intradialytic
hypotensive episodes ; ( 4 ) individualizing the initial dialysis prescription with consideration of an incremental / infrequent approach to hemodialysis initiation ( e.g. -
pubmed
The
patients were separated into two groups as histologically observed
prostatitis ( Group A ) and no
prostatitis ( Group B ) according to the biopsy outcomes . -
pubmed
Mean international prostate symptom score in
patients with
prostatitis was numerically but not significantly higher than that in those without
prostatitis ( t=0.794 , P=0.066 ) . -
pubmed
Histological
prostatitis notably affected sexual function of
patients and may serve as a major risk factor for
sexual dysfunction while having little effect on
lower urinary tract symptoms . -
pubmed
We attempt to dissect the pathology of
non - small cell lung cancer (
NSCLC )
patients at different stages and discover the novel candidate genes . -
pubmed
Impact of groin flap
ischemia - reperfusion on red blood cell micro - rheological parameters in a follow - up study on
rats . -
pubmed
Patients were retrospectively classified into two groups based on whether they developed severe
sepsis or
septic shock during the postoperative period . -
pubmed
BACKGROUND :
Posaconazole is approved for invasive
fungal infection prophylaxis in
patients with
hematologic malignancies . -
pubmed
OBJECTIVES : We sought to determine if a switch to
posaconazole tablets improved steady - state drug level attainment for invasive
fungal infection prophylaxis in
patients with
acute myeloid leukemia . -
pubmed
METHODS : All adult
inpatients with
acute myeloid leukemia undergoing chemotherapy , who received
posaconazole for invasive
fungal infection prophylaxis between 2012 and 2015 , were included . -
pubmed
Secondary outcomes included proportion of
patients with first
posaconazole level greater than 1000 ng / mL , invasive
fungal infection within 100 days , and
adverse drug events . -
pubmed
Scaffold - supported Transplantation of Islets in the Epididymal Fat Pad of
Diabetic Mice . -
pubmed
Here , we report a robust protocol for the transplantation of islets at the extrahepatic transplantation site - the epididymal fat pad ( EFP)-in a
diabetic mouse model . -
pubmed
We present the first direct evidence that
B19V infection of erythroid progenitor cells disrupts the
human genome and facilitates viral DNA integration . -
pubmed
OBJECTIVE : To evaluate the role of quantitative digital subtraction angiography ( Q - DSA ) with parametric color coding ( PCC ) in assessing
patients with
type B chronic thoracic aortic dissection (
TBCAD ) during thoracic endovascular aortic repair ( TEVAR ) procedures . -
pubmed
CONCLUSIONS : Our results indicate that Q - DSA could be useful in the intraprocedural evaluation of
patients with
aortic dissection during TEVAR procedures without additional x - ray costs and contrast exposure . -
pubmed
Laboratory impacts were performed at 12 locations distributed over the helmet and the resulting head kinematics were simulated in two finite element models of the brain : the Simulated
Injury Monitor and the Global
Human Body Model Consortium brain model . -
pubmed
Methods : Sixty - four male
nude mice bearing
tumor xenografts were randomly divided into four groups . -
pubmed
Cell culture was performed using the
human gastric adenocarcinoma cell line
SGC-7901 . -
pubmed
Mice with
tumor xenografts were treated with
propranolol ,
isoproterenol , and radiation . -
pubmed
Results : The growth in the volume and weight of the
tumor was lower in
mouse models treated with
propranolol and radiation therapy compared to the other groups . -
pubmed
The percentage of circulating Th17 and Th22 cells was significantly increased in
CC patients compared to that in healthy controls ( HCs ) . -
pubmed
The
patient was diagnosed with
small bowel obstruction and taken for exploratory laparotomy . -
pubmed
In addition to 10 control
patients with no
ED or chronic
HCV ( Group D ) . -
pubmed
There were significant differences in Hcy between patients with Child B and Child C. A strong association between severity of
ED and chronic
HCV was demonstrated . -
pubmed
Indocyanine green fluorescence - imaging ( ICG - FI ) has emerged as a potential tool for increasing the accuracy of staging of
patients with primary
colorectal cancer (
CRC ) through the detection of sentinel lymph nodes ( SLNs ) . -
pubmed
ICG - FI is a promising technique for the detection of SLNs in the setting of
CRC but more work needs to be done to clearly define protocols and indications for its use and to test its efficacy in larger
patient populations . -
pubmed
HHH is the rarest of the
urea cycle disorders , reported in fewer than 100
patients . -
pubmed
To model chronic
migraine C57BL/6J
mice received chronic intermittent treatment with the known
human migraine trigger ,
nitroglycerin . -
pubmed
For MOH and
OIH ,
mice were chronically treated with
sumatriptan or
morphine , respectively . -
pubmed
In addition , we showed that MNCaposec accelerated
wound closure in a
diabetic mouse model . -
pubmed
Effect of laminar air flow and building construction on
aspergillosis in
acute leukemia patients : a retrospective cohort study . -
pubmed
BACKGROUND : The preventive effect of laminar air flow ( LAF ) on
aspergillosis has been observed in
patients with
hematological malignancies . -
pubmed
METHODS : To assess the preventive effect of long - term LAF use on
aspergillosis in its long - term use , we retrospectively analyzed 124
acute leukemia patients at our hospital between January 2005 and March 2016 . -
pubmed
RESULTS : Fourteen
patients were diagnosed with possible , probable , or definite
aspergillosis . -
pubmed
INTRODUCTION : In
patients with
liver lesions with ductal extension , the corresponding Glissonean pedicle should be divided at its origin to achieve a negative ductal margin ; however , during laparoscopic hepatectomy , it is difficult to precisely transect the liver and divide the Glissonean pedicle as planned . -
pubmed
Typical enteropathogenic
Escherichia coli ( typical
EPEC ) and Cryptosporidium were the two pathogens associated to an increased risk of
death in the univariate analysis with ( HR = 4.16 , p = 0.0461 ) and ( H = 2.84 , p = 0.0001 ) respectively . -
pubmed
When restricting the analysis to those with available
HIV results ( n = 191 , 22 % of the total study sample ) ,
HIV was shown to be a significant risk factor for
death ( HR = 5.05 , p = 0.0009 ) . -
pubmed
Verbal autopsies were conducted in 100 % of study
deaths , and highlighted
diarrhea as the main underlying cause of
death 39 % , ( 27/69 ) ; followed by
HIV /
AIDS related
deaths 29.0 % ( 20/69 ) and
sepsis 11.6 % ( 8/69 ) . -
pubmed
RESULTS : Two of 44 ( 5 % )
patients had
bone marrow involvement . -
pubmed
These two
patients had no
relapse during follow - up , either cutaneous or extra - cutaneous . -
pubmed
Animal model of
arthritis and
myositis induced by the
Mayaro virus . -
pubmed
BACKGROUND : The
Mayaro virus (
MAYV ) is an endemic arbovirus in South American countries , where it is responsible for sporadic outbreaks of
Mayaro fever . -
pubmed
For
pain analysis , the
animals were submitted to the von Frey test and titre in different organs was evaluated throughout the study to obtain viral kinetics . -
pubmed
Airway clearance techniques for
patients with acute exacerbations of
chronic obstructive pulmonary disease : Physical therapy practice in Sweden . -
pubmed
Efficacy and safety results from a phase 1b/2 , multicenter , open - label study of
oprozomib and
dexamethasone in
patients with relapsed and/or refractory
multiple myeloma . -
pubmed
Our phase 1b/2 study examined the safety and efficacy of
oprozomib with
dexamethasone in
patients with
relapsed and refractory MM . -
pubmed
Influence of shortened recovery between resistance exercise sessions on
muscle - hypertrophic effect in
rat skeletal muscle . -
pubmed
To elucidate the effect of recovery period on
hypertrophy , in the present study , we investigated changes in protein degradation systems and
hypertrophic responses in
rat skeletal muscle to resistance training with variable recovery periods . -
pubmed
Prophylactic
simvastatin treatment modulates the immune response and increases survival of
mice following induction of lethal
sepsis . -
pubmed
Development of antifungal agents with novel mechanism and low toxicity are essential due to the prevalence of the
infectious diseases caused by
Candida albicans . -
pubmed
BACKGROUND :
Pazopanib can induce
liver toxicity in
patients with
metastatic renal cell carcinoma (
mRCC ) . -
pubmed
RESULTS : Of 261
patients , 34 ( 13 % ) had developed
liver toxicity after a median of 29 days ( range , 5 - 155 days ) . -
pubmed
Degenerative cervical myelopathy (
DCM ) is the leading cause of
spinal cord dysfunction in
adults worldwide . -
pubmed
OBJECTIVES : To compare the prognostic role of FVC and SVC at diagnosis in
amyotrophic lateral sclerosis (
ALS )
patients . -
pubmed
METHODS : We included all
patients from the Piemonte and Valle D'Aosta
ALS register ( PARALS ) who had been diagnosed with
ALS between 1995 and 2015 and underwent spirometry at diagnosis . -
pubmed
RESULTS : A total of 795
ALS patients underwent spirometry at diagnosis during the study period . -
pubmed
A 54 - year - old Japanese
woman presented with acute severe
neck pain . -
pubmed
The
patient was diagnosed with acute
calcific retropharyngeal tendinitis and treated with a soft collar and non - steroidal anti - inflammatory drugs . -
pubmed
BACKGROUND : Front - loaded
diazepam is used to rapidly control
agitation in
patients with severe
alcohol withdrawal syndrome (
AWS ) . -
pubmed
Patients who received front - loaded
lorazepam had an increased incidence of ICU -
delirium ( positive for the
Confusion Assessment Method in the ICU : 75 % with
lorazepam vs. 52.6 % with
diazepam , p = 0.009 ) and a higher risk of over - sedation , but this did not reach statistical significance ( Richmond Agitation - Sedation Scale score < -1 : 32.1 % with
lorazepam vs. 18.2 % with
diazepam , p = 0.063 ) . -
pubmed
The aim of this work was to investigate on the
animal model of
metabolic syndrome , i.e. -
pubmed
Administration of
venlafaxine caused the decrease of heart weight /
body weight index in
rats fed with HFFD compared to the untreated group fed with HFFD for 8 weeks . -
pubmed
BACKGROUND :
Coronavirus disease 2019 ( Covid-19 ) occurs after exposure to
severe acute respiratory syndrome coronavirus 2 (
SARS - CoV-2 ) . -
pubmed
Whether
hydroxychloroquine can prevent symptomatic
infection after
SARS - CoV-2 exposure is unknown . -
pubmed
This is the first demonstration of a microRNA OE
mouse model that has
ectodermal organ defects . -
pubmed
Patients were classified according to HRCT findings into five groups : usual
interstitial pneumonia (
UIP ) , non - specific
interstitial pneumonia (
NSIP ) , desquamative
interstitial pneumonia (
DIP ) , combined
pulmonary fibrosis and
emphysema (
CPFE ) , and
non - specific - ILD . -
pubmed
Neoadjuvant Biologic Therapy in the Surgical Management of
Patients with
Hidradenitis Suppurativa : A Cohort Study . -
pubmed
For
rabbits , boosts should be spaced every 6 wk , and serum samples of 20 - 40 mL should be collected ~10 - 12 d after each boost ; typically , a single sample
bleed from a
rabbit will yield 25 mL of serum . -
pubmed
Anti -
rheumatoid arthritis effects of
iridoid glucosides from
Lamiophlomis rotata ( Benth . ) -
pubmed
In a 4 - week intervention trial ,
overweight subjects were randomized to consume either arabinoxylan -
oligosaccharides ( AXOS ) ( 10.4 g / d ) from
wheat bran or
polyunsaturated fatty acids (
PUFA ) ( 3.6 g / d ) . -
pubmed
Refractory disease is a major challenge in treating
patients with
acute myeloid leukemia (
AML ) . -
pubmed
Influenza in China in 1977 :
recurrence of
influenzavirus A subtype H1N1 . -
pubmed
The
influenza epidemic caused by the
H1N1 virus was characterized by slow spread , unevenness of attack rates , and the occurrence of many mild cases and inapparent
infections . -
pubmed
[ Therapeutic and protective regimen for
children with
chronic pneumonia ] . -
pubmed
The successful surgical removal of a feminizing
adrenal tumour in a postmenopausal
woman is described . -
pubmed
Recurrent
ventricular tachyarrhythmias required multiple resuscitative efforts with electrical countershock in a 45 - year - old
woman with previously undiagnosed asymptomatic congenital prolongation of the Q - T interval . -
pubmed
The results of brain scanning in 64
patients with histologically proven
meningiomas are presented , and the accuracy of this diagnostic method is assessed . -
pubmed
Primitive neuroectodermal tumor (
neuroblastoma ) arising in sciatic nerve of a
child . -
pubmed
A well - documented case of a primitive
neuroectodermal tumor (
neuroblastoma ) arising in the sciatic nerve of a 6 - year old
boy is presented . -
pubmed
After radical surgical excision of the
tumor , followed by chemotherapy , the
child remained clinically free of disease for 20 months . -
pubmed
The incidence and type of x - ray semeiotics of the skull involvement were studied in 703
patients with
endocrine diseases ( 26 with
acromegaly , 36 with
hypercorticism , 104 with
thyrotoxicosis , 23 with
hypothyrosis , 98 with
primary hyperparathyrosis , 302 with
diabetes mellitus , 114 with
hypogonadism ) . -
pubmed
However , a
strain of
V. - pubmed
In the present study , only mobile , relatively healthy , adequately nourished
outpatients with probable
AD were selected . -
pubmed
In comparison to age - matched controls or demented subjects with even mild indications of vascular contributions , the
AD subjects were characterized by lower serum
PO4 and , to a lesser degree , lower serum
Ca as well as a higher
chloride /
PO4 ratio . -
pubmed
from the control group mean ) identified 74 % of all
AD subjects and 100 % of early onset
AD subjects , in comparison to only 46 % of mixed /
vascular dementia subjects and 31 % of normal age - matched controls . -
pubmed
Adherence of
Candida albicans to tissues from
mice with
genetic immunodeficiencies . -
pubmed
In general ,
immunodeficiencies significantly decreased binding of
C. - pubmed
Underutilization of thrombolytic therapy in eligible
women with
acute myocardial infarction . -
pubmed
Twenty - three lines of
chickens , obtained from grandparent stocks of 4 Australian breeding companies , were analysed to determine the incidence of early embryonic mortality attributable to
chromosome abnormalities . -
pubmed
The lines included 10 layer
strains , consisting of 6
White Leghorn , 2 New Hampshire and 2 Australorp lines , and 13 broiler lines . -
pubmed
Bypass to the pedal arteries was performed with use of the operating microscope and standard microsurgical technique in 37
patients with severe , chronic
ischemia of a lower extremity . -
pubmed
Twenty - one
patients ( 57 % ) had three or more cardiovascular risk factors , and 22 ( 59 % ) had
diabetes . -
pubmed
No early
deaths occurred , and only one
patient had a perioperative
myocardial infarction . -
pubmed
Of the 34
patients who were alive at the time of this report , 27 ( 79 % ) had a functional foot that allowed ambulation , had no
rest pain , and had no substantial loss of tissue . -
pubmed
Pedal bypass should be considered for critical , chronic
ischemia , even if the
patient has an increased surgical risk and advanced distal
atherosclerotic disease . -
pubmed
[ The late results of the combined treatment of
kidney cancer patients ] . -
pubmed
Randomized study with inclusion of certain types of immunotherapy in the schedule of complex treatment was conducted in 89
patients with
kidney carcinoma after the operation . -
pubmed
In 63
patients the
tumor was in stage T3N0M0 . -
pubmed
Multiple
metastases occurred in 26
patients . -
pubmed
Measures for increasing the activity of the immune and macrophagal systems should be included in the schedule of complex treatment for
patients with
carcinoma of the kidney . -
pubmed
To evaluate premarital
human immunodeficiency virus (
HIV ) screening as an approach to
AIDS prevention in the United States , we determined the
HIV antibody seroprevalence in marriage license applicants in eight areas by blinded testing of blood specimens routinely collected for
syphilis serology . -
pubmed
An 8 - year - old
boy , presenting with signs of
chronic meningitis , and involvement of cranial nerves , was found to have
neurobrucellosis . -
pubmed
The development of
angiotensin - converting enzyme ( ACE ) inhibitors has been important in furthering our understanding of the pathophysiology of
congestive heart failure and improving the care of these
patients . -
pubmed
ACE inhibitors have been shown to improve the longevity and quality of life of
patients with
congestive heart failure . -
pubmed
, 216
Haemophilus parainfluenzae and 28
Haemophilus influenzae strains being isolated . -
pubmed
Female ( NZBxNZW)F1
mice were fed for one month with a diet in which the sources of fat were either melted beef tallow or
fish oil , the latter regimen being associated with a marked decrease in the expression of auto -
immune disease in these animals . -
pubmed
To test whether or not this beneficial effect was associated with an increased risk of
infection , animals fed each of these diets were challenged intraperitoneally with graded doses of four different classes of microorganisms : a gram positive bacillus that is an intracellular parasite (
Listeria monocytogenes ) , an exotoxin - producing gram negative bacillus (
Pseudomonas aeruginosa ) , a
yeast (
Candida albicans ) , and a
herpes group virus (
murine cytomegalovirus ) . -
pubmed
We conclude that the beneficial anti - inflammatory effects of
fish oil diets in these
mice are not associated with an increased risk of
infection with a variety of microbial agents . -
pubmed
[
Acute diseases of the gallbladder and pancreas in
patients with severe
trauma and
shock ( characteristics of the diagnosis and treatment ) ] . -
pubmed
Under study were 56 observations of
posttraumatic cholecystitis and
pancreatitis in
patients with
polytrauma without a direct
injury of the gallbladder and pancreas . -
pubmed
Apomorphine - induced
rotation was significantly suppressed in 11 out of 26
rats from two through ten weeks after the implantation . -
pubmed
Two groups of
rats were treated for
epididymitis in an experimental study . -
pubmed
The developing
infection of
E. - pubmed
A subgroup of seven resection
patients without fat and
bile acid malabsorption served as controls . -
pubmed
Of the resection
patients , eight had a pure
bile acid malabsorption and 15 a combination of fat ,
bile acid , and modest
cholesterol malabsorption . -
pubmed
The concentrations of the precursor
sterols were similarly increased in the
subjects with
bile acid and cholesterol malabsorption , the two
lathosterols showing the highest correlations with the overall
cholesterol synthesis ( r = 0.820 - 0.941 ) . -
pubmed
In the
subjects with jejunoileal bypass
cholesterol malabsorption effectively regulated
cholesterol synthesis and the precursor levels . -
pubmed
Metronidazole significantly improved the results in the
anaemic cases , but had no effect on the non - anaemic
patients . -
pubmed
It is concluded that
anaemia has a prognostic value , and
anaemic patients may represent a particular group for which hypoxic cell sensitizers can be expected to improve the effect of radiotherapy . -
pubmed
Necropsy findings in a
child with
FG syndrome . -
pubmed
We conducted a prospective investigation of the effect of coffee consumption on
coronary heart disease in 1130 male medical
students who were followed for 19 to 35 years . -
pubmed
Coronary " calcific " embolisation must be considered in the differential diagnosis of symptoms of
ischemic heart disease in
patients suffering from
valvular heart lesions . -
pubmed
In twenty - four
patients with
intolerance to cold after partial or complete finger amputations , lower skin temperature together with cold and vibration
allodynia (
allodynia =
pain due to a non - noxious stimulus to neural skin ) were found in the cold intolerant area compared with the corresponding area in the uninjured hand . -
pubmed
The
patients had several features in common with
reflex sympathetic dystrophies , and we suggest that neurogenic rather than vascular disturbances are mainly involved in the
post - traumatic cold intolerance syndrome . -
pubmed
Slices of
human prostatic adenocarcinoma obtained by transurethral resection were maintained in organ culture for 4 days . -
pubmed
Inhibition by H-1 virus of the incidence of
tumors produced by adenovirus 12 in
hamsters . -
pubmed
Multiple
infections among newborns resulting from colonization with
Staphylococcus aureus 502A. -
pubmed
They inhibited the
hypotensive effect of SP in the anesthetised
rats , the vasodilator effect in the
rabbit perfused heart and the relaxation induced by SP in
dog carotid arteries contracted with
noradrenaline . -
pubmed
Proximal renal tubular function was studied in 11
patients with severe
burn injury . -
pubmed
Twenty - four - hour urine
glucose excretion exceeded 1 g in five
patients ,
aminoaciduria was noted in eight , and
proteinuria , predominantly
globulinuria , was present consistently . -
pubmed
Metabolic acidosis was seen in one
patient , and transient
hypokalemia occurred in two . -
pubmed
Abnormalities of proximal tubular function were more marked in the five
patients with the greatest extent of third - degree
burns who died . -
pubmed
In all 3 cases when
captopril ( 0.3 mg / Kg ) was administered intravenously to donor
dogs , the blood pressure decreased and a slight
tachycardia usually appeared . -
pubmed
The
Alaska salmon industry conducted 9 recalls of 7 3/4 - oz cans of salmon in 1982 after a 7 3/4 - oz can of
Alaskan salmon was implicated in illness and one
death in Belgium from
Clostridium botulinum type E toxin . -
pubmed
Collagens extracted from bones , cartilage , dermis , and dura mater of an
infant with
type II ( lethal perinatal ) osteogenesis imperfecta were evaluated with respect to chain composition and chemical characteristics of their constituent chains . -
pubmed
One - year survival is infrequent in
patients with
metastatic cancer to the liver . -
pubmed
The subset of
patients ( 16 ) with colorectal
adenocarcinoma had a 7 - year survival rate of 29 % after hepatic resection . -
pubmed
We conclude that hepatic resection for isolated
hepatic metastases can be performed with acceptable morbidity , low mortality , and prolongation of
patient survival . -
pubmed
Using the incomplete
cerebral hemisphere infarction in
dogs , we have been able to produce
brain swelling in all
animals after six hours of
vascular occlusion followed by recirculation of blood . -
pubmed
Noteworthy is the fact that among these experimental groups , there were
animals in which
brain swelling was severe , yet extravasation of Evans blue was slight and , contrarily ,
animals in which
brain swelling was slight but extravasation severe . -
pubmed
To gain insight into the operative mechanism of
RA and to study the agreement between the two quantitative angiographic methods in measuring the minimal luminal cross - sectional area , the edge detection and videodensitometry techniques were applied to coronary angiograms of 21 lesions in 19
patients with symptoms who underwent successful RA and balloon angioplasty ( BA ) . -
pubmed
Acute myelopathy in
children . -
pubmed
Because of the high risk of
adenocarcinoma in
Barret ' s esophagus , endoscopic surveillance of all
patients with acceptable surgical risk is recommended . -
pubmed
The remote phylogenetic relationship between the two bird parasites ,
Plasmodium gallinaceum and
Plasmodium lophurae , and any of the
human parasites provides no support for the hypothesis that
infection by
Plasmodium falciparum is a recent acquisition of
humans , possibly coincident with the onset of agriculture . -
pubmed
Between 1980 and 1990 we treated 12
patients ( median age 43 years , range 16 - 62 ) with
collecting duct carcinoma of the kidney . -
pubmed
They induce
hepatocellular carcinoma in
rats and
birds , and are suspected of being carcinogenic to
humans . -
pubmed
To better understand the
genotoxic effects of
PCBs , we used
32P - postlabelling to investigate DNA adduct formation , after exposure to
PCBs (
Aroclor 1254 and
3,3 ' , 4,4 '- tetrachlorobiphenyl ) , in primary cultures of fetal hepatocytes from two
animal species and in a
human cell line (
Hep G2 ) . -
pubmed
Remodeling rather than neointimal formation explains luminal narrowing after
deep vessel wall injury : insights from a
porcine coronary ( re ) stenosis model . -
pubmed
BACKGROUND : Oversized balloon dilatation of normal
porcine coronary arteries usually heals without
stenosis formation . -
pubmed
In 9
pigs ( group 2 ) examined postmortem 3 weeks after dilatation , histology revealed that the
injury was deep ( out to adventitia ) in all arteries and completely circumferential ( 360 degrees ) in all but two arteries . -
pubmed
METHODS :
PC-3 human prostate carcinoma cells were exposed to 50 - 200 nM
jasplakinolide (
Jas ) or
cytochalasin E (
CyE ) in
cytotoxicity experiments . -
pubmed
Effective treatment of the multiply injured
trauma patient . -
pubmed
We describe a newborn
girl who had been exposed to
idarubicin and
cytosine - arabinoside during the second and third trimesters of pregnancy due to treatment of newly diagnosed
acute myeloid leukemia in the mother . -
pubmed
The
child had no structural
congenital abnormalities . -
pubmed
However , 2 of the 6
patients whose ALs continued experienced a
pneumothorax . -
pubmed
After - the - fact strategies Mexican Americans use to prevent
HIV and
STDs . -
pubmed
Their preventive practices for both
HIV and STDs centered around a "
gonorrhea model " of prevention and casual transmission . -
pubmed
METHODS : Inflamed sigmoid colon epithelium from
UC patients was studied by alternating current impedance analysis to determine the pure epithelial resistance as a measure of intestinal barrier function . -
pubmed
Photodynamic therapy in
women with
cervical intraepithelial neoplasia using topically applied
5 - aminolevulinic acid . -
pubmed
We performed a study of topically applied
5 - aminolevulinic acid (
5 - ALA ) in the photodynamic treatment of
women with high - grade
cervical intraepithelial neoplasia (
CIN ) using fixed
5 - ALA doses and application protocols derived from previous in vitro and in vivo results . -
pubmed
Ten treatment cycles of PDT using
5 - ALA were performed in 7
patients with high - grade
CIN . -
pubmed
Local
toxicity was minor as several
patients reported burning sensations and
vaginal discharge , but no
necrosis , sloughing or
scarring occurred . -
pubmed
RESULTS :
Mice sensitized and challenged with pollen developed clinical signs consistent with
human allergic conjunctivitis . -
pubmed
All the
human strains were
gentamicin sensitive , while
streptomicin and
cloxacillin were resistant . -
pubmed
Erythromycin had a high activity ( 83.3 % ) on
human strains and only 59.6 % activity on animal
strains . -
pubmed
In an in vivo study , employing
nitrosomethylurea - induced
mammary tumours in intact
rats ,
2 - MeOE1 ( 20mg / kg / d , p.o . -
pubmed
MATERIAL AND METHODS : An open cross - over randomised trial enrolled 29
anginal patients . -
pubmed
10
patients retained signs of
myocardial ischemia at BE though they were treated with specially selected antianginal drugs . -
pubmed
Continuous
lamivudine treatment in an
OLT patient despite the appearance of
HBV resistant
strain : longitudinal analysis . -
pubmed
Primary locally infiltrative gastrointestinal
aspergilloma in a non - neutropaenic
child . -
pubmed
The
patient finally died due to
sepsis and
gastrointestinal bleeding . -
pubmed
In
stroke patients , brain SPECT images with
Tc-99 m HMPAO can predict fatal
cerebral hemorrhage caused by anti - thrombic therapy by showing the decrease in count ratio ( count ratio of infarcted to contralateral area of & lt ; 0.34 ) in the acute phase and identifying disruption of the blood brain barrier by showing hyperfixation in the subacute phase . -
pubmed
Model systems : modeling
human staphylococcal arthritis and
sepsis in the
mouse . -
pubmed
Murine models of
Staphylocococus aureus - mediated
arthritis and
sepsis exist and are being used to gain a better understanding of the host - bacterium relationship as well to develop better methods of prevention and treatment . -
pubmed
BACKGROUND : Nowadays a number of diverse biochemical markers have been identified in
patients with
heart failure (
HF ) that could indicate the severity of the patients ' illness . -
pubmed
PATIENTS AND METHOD : We studied 114
patients admitted consecutively for symptomatic
HF for all causes ( age : 66 years , male : 60 % ) . -
pubmed
One of the C - peptides , T-20 , which is in the phase III clinical trials , has potent in vivo activity against
HIV infection and is expected to become the first peptide
HIV fusion inhibitory drug in the near future . -
pubmed
The aim of the present study was to evaluate both clinical features and treatment in a subgroup of
patients with ruptured
liver tumours . -
pubmed
From 1995 to 2000 , 20
patients were referred to our centre for
spontaneous rupture of a
liver tumour associated with
haemoperitoneum . -
pubmed
Hepatocellular carcinoma (
HCC ) was present in 13
patients ( 11
men and 2 women ) aged from 48 to 72 years ( mean 62 ) and
adenoma in 7 women aged from 23 to 52 years ( mean 35 ) . -
pubmed
In
patients with
HCC , severe
liver insufficiency ( Child - Pugh C ) was present in 5 cases including the 3 shocked
patients . -
pubmed
In hospital , mortality was observed in 3 ( 23 % )
patients , all of them had severe
liver insufficiency . -
pubmed
In
patients with
adenoma ,
shock at admission was observed in only 1
patient under anticoagulation treatment . -
pubmed
A decrease of the
tumour size was observed in
patients who underwent delayed resection resulting in a lower rate of peri - operative transfusion . -
pubmed
In conclusion , this study confirms that the majority of
patients with ruptured
liver tumours had no evidence of haemodynamic instability and therefore should be initially managed conservatively . -
pubmed
In
patients with single ruptured
HCC associated with good liver function , long - term survival can be observed after liver resection . -
pubmed
Delayed resection facilitated the operative procedure in
patients with ruptured
adenoma . -
pubmed
The incidence of mandibular ORN in
head and neck cancer patients managed with radical or postoperative irradiation , has varied widely in the literature from 0.4 % to 56 % . -
pubmed
Numerous factors that may be associated with the risk of
ORN include treatment - related variables ( for example , total radiotherapy dose , biologically effective dose , photon energy , brachytherapy dose rate , combination of external beam irradiation and interstitial brachytherapy , field size , fraction size , volume of the mandible irradiated with a high dose ) ,
patient - related variables ( like
deep parodontitis , pre - irradiation bone surgery , bad oral hygiene ,
alcohol and
tobacco abuse ,
bone inflammation , dental extraction after radiotherapy ) and tumour - related factors (
tumour size or stage , proximity of the
tumour to bone , anatomic
tumour site ) . -
pubmed
Anxiety disorders in
children : intervention strategies for the primary care setting . -
pubmed
Ginkgo biloba for the prevention and treatment of
cardiovascular disease : a review of the literature . -
pubmed
We reported a 29 - year - old
woman with
McArdle ' s disease accompanied with
insulin resistance . -
pubmed
Phencyclidine (
PCP ) is a drug of abuse that has rewarding and
dysphoric effects in
humans . -
pubmed
Pharmacological treatment of motor features is disappointing except for a transient
L - Dopa response in a minority of
MSA - P patients . -
pubmed
CONCLUSION : Both
Lactobacillus salivarius 433118 and
Bifidobacterium infantis 35624 significantly attenuate
colitis in this
murine model . -
pubmed
However , using this protocol , it is still difficult to induce long - term regression in established
tumor - bearing
mice . -
pubmed
Removal of one of these cellular components during vaccination resulted in failure to completely cure
tumor - bearing
mice . -
pubmed
Two
patients had unilateral grade 1
sacroiliitis , one
patient grade 4
sacroiliitis , and one
patient bilateral grade 2
sacroiliitis . -
pubmed
CONCLUSION : The results of the initial study showed that long term treatment with
lymecycline in
patients with acute
ReA decreased the duration of
arthritis in those with
Chlamydia trachomatis triggered
ReA , but not in other
patients with
ReA. -
pubmed
Ten years after the acute
arthritis one
patient had developed
AS , and three had radiological
sacroiliitis , three
patients had radiological changes at peripheral joints . -
pubmed
[
Ammonium content in leaves in
Fusarium infection of
melons ] . -
pubmed
[ Preoperative and postoperative studies on
blood coagulation components and on fibrinolytic activity in surgical
patients ] . -
pubmed
Specific measurements were taken on both sides of 26 Turkish
human male skulls , none of which showed any obvious pathology or
trauma . -
pubmed
PURPOSE : The advent of endovascular prostheses to treat
descending thoracic aortic lesions offers an alternative approach in
patients who are poor candidates for surgery . -
pubmed
METHODS : We conducted a retrospective review of 60 emergent and high - risk
patients with
thoracic aortic aneurysms (
TAAs ) and dissections treated with endovascular prostheses over 4 years under existing investigational protocols or on an emergent compassionate use basis . -
pubmed
Thirty - five
patients received treatment of
TAAs . -
pubmed
Twenty - four
patients with
aortic dissections ( 16 acute , 8 chronic ) also received treatment . -
pubmed
Eight of the
patients with acute dissection had active
hemorrhage at the time of treatment . -
pubmed
One
patient underwent surgical repair of a retrograde ascending
aortic dissection after endograft placement . -
pubmed
CONCLUSION : Although significant morbidity and mortality remain , endovascular repair of descending
TAAs and dissections in
patients at high - risk patients can be accomplished with acceptable outcomes compared with traditional open repair . -
pubmed
Evaluation of brainstem auditory potential in
brucellosis patients with and without neurological involvement . -
pubmed
Twenty - two
patients with
brucellosis without
neurologic involvement and seven
patients with
neurobrucellosis were included . -
pubmed
Patients who had
neurologic involvement did not show any abnormalities in their BAEPs recording . -
pubmed
This study suggests that
patients with
brucellosis who are in the acute phase of the disease with or without
neurological involvement may have normal BAEPs . -
pubmed
BAEPs do not seem to be a sensitive method for central nervous system involvement of
brucella patients in the acute phase of the disease . -
pubmed
BACKGROUND & amp ; AIMS : Although
hepatitis C virus kinetics and immune determinants during primary
infection have been described , the virus - host interplay is not fully understood . -
pubmed
Effect of
Mornidae Radix extracts on experimental
osteoporosis in sciatic neurectomized
mice . -
pubmed
The preventive and therapeutic effects of aqueous extracts of
Mornidae Radix ( MR ) were observed in sciatic neurectomized
mice , a disused
osteoporotic model . -
pubmed
One
woman chose vacuum aspiration for termination of the abortion on day 3 of the induced
bleeding . -
pubmed
In this multicentre , placebo - controlled , 16 - week trial , the efficacy and safety of
oxcarbazepine monotherapy in
patients with
neuropathic pain of
diabetic origin was evaluated . -
pubmed
Eligible
patients had a 6 - month to 5 - year history of
neuropathic pain symptoms of diabetic origin and a
pain rating of & gt ; or = 50 units on the visual analogue scale ( VAS ) . -
pubmed
Patients on
oxcarbazepine were awakened less frequently due to
pain than
patients on placebo . -
pubmed
These observations suggest that
oxcarbazepine monotherapy , pending additional trials , may be efficacious and may provide clinically meaningful
pain relief in
patients with
neuropathic pain of
diabetic origin . -
pubmed
BACKGROUND :
Osteosarcoma (
OSA ) is the most frequent type of primary
malignant bone tumor and is apt to occur in
children and young
adults . -
pubmed
METHODS : We detected OC mRNA expression by RNA in situ hybridization in
OSA and OSPM samples from
patients , and tested OC promoter transcriptional activity in
OSA and non - OSA cell lines . -
pubmed
[ Effects of
norcantharidin on angiogenesis of
human gallbladder carcinoma and its anti - angiogenic mechanisms ] . -
pubmed
OBJECTIVE : To investigate the effects of
norcantharidin (
NCTD ) on angiogenesis of
human gallbladder carcinoma and its anti - angiogenic mechanisms . -
pubmed
METHODS :
Human gallbladder carcinoma cells of the line
GBC - SD were cultured . -
pubmed
The short - term precision of QUS was investigated with regard to BMI of healthy individuals and with regard to the level of disease activity in
patients suffering from
RA . -
pubmed
The
patients with
RA were divided into two
BMI groups as well as into low and advanced disease activity groups . -
pubmed
Pathogenesis , laboratory diagnosis , and clinical implications of
erythrocyte enzyme deficiencies in
dogs ,
cats , and
horses . -
pubmed
Animals with
pyruvate kinase ( PK ) or phosphofructokinase ( PFK ) deficiencies have shortened erythrocyte life spans and regenerative
anemia . -
pubmed
PK - deficient dogs ( but not
PK - deficient cats ) develop progressive
myelofibrosis and
osteosclerosis of bone marrow and
hemochromatosis and
cirrhosis of the liver . -
pubmed
PFK - deficient dogs have sporadic episodes of
hyperventilation - induced
intravascular hemolysis and
hemoglobinuria . -
pubmed
Cytochrome b5 reductase ( Cb5R ) deficiency in
dogs and
cats results in persistent
methemoglobinemia and
cyanotic mucous membranes . -
pubmed
Horses with
erythrocyte flavin adenine dinucleotide ( FAD ) deficiency have both
eccentrocytosis ( attributable to severe
deficiency in glutathione reductase activity ) and
methemoglobinemia ( attributable to
Cb5R deficiency ) ; the dual enzyme deficiency occurs because
FAD is a required cofactor for both enzymes . -
pubmed
Erythrocyte enzyme deficiencies do not usually shorten life expectancy , except for
PK - deficient dogs and potentially
PFK - deficient dogs during a
hemolytic crisis . -
pubmed
Although
enzyme deficiencies are rare causes of
anemia and
methemoglobinemia , the ability to diagnose deficient
animals allows for the possibility of eliminating these undesirable traits in future breeding . -
pubmed
Chiropractic management of
cow 's milk protein intolerance in infants with
sleep dysfunction syndrome : a therapeutic trial . -
pubmed
OBJECTIVE : In addition to the more usual cutaneous , gastrointestinal , and respiratory problems , infants with
cow 's
milk intolerance (
CMI ) may present with a
disturbed sleep pattern . -
pubmed
Infants fulfilling a clinical screening protocol for
CMI were selected for a therapeutic trial . -
pubmed
PATIENTS AND METHODS : Thirty - one female
patients with operable
breast cancer consented to immediate breast reconstruction during the period from June 1998 to December 2000 . -
pubmed
In the pedicled flap group , two
patients ( 10.5 % ) experienced partial flap loss and
fat necrosis was detected in two other
patients . -
pubmed
For the free flap group , two
patients ( 13.3 % ) developed complete flap loss , but none suffered fat
necrosis . -
pubmed
None of the
patients in both groups developed
abdominal wall hernia , but
abdominal wall weakness was evident in eight
patients in the pedicled flap group that gradually improved over 2 - 3 months . -
pubmed
The induction of complete transformation of the
human breast epithelial cell
MCF-10F in vitro confirms the carcinogenicity of E(2 ) , supporting the concept that this hormone could act as an initiator of
breast cancer in women . -
pubmed
OBJECTIVES : In the current study we describe and characterize a novel
ovine model of
biventricular hypertrophy and
heart failure and evaluate the role of selected cardiac transcription factors in the regulation of cardiac gene expression during pathologic
hypertrophy in vivo . -
pubmed
CONCLUSION : The shunted neonatal
lamb is a valid , novel model of pathologic
biventricular hypertrophy . -
pubmed
To define this relationship , we assessed a large cohort of
women following first recognized obstetric
anal sphincter injury . -
pubmed
STUDY DESIGN : In all , 500 consecutive
women were studied at 3 months following primary repair of a first recognized obstetric
anal sphincter injury sustained during vaginal delivery . -
pubmed
MATERIAL AND METHOD : the study complied 36
children aged 4 months - 3 years treated in the Department of
Children Allergology , Gastroenterology and Nutrition because of
atopic dermatitis . -
pubmed
It seems that
animal hair and food allergens are mainly responsible for development of
atopic dermatitis . -
pubmed
The long - term outcome of
patients with bleeding
gastric varices after balloon - occluded retrograde transvenous obliteration . -
pubmed
BACKGROUND : The purpose of our study was to evaluate the long - term outcome and complications of balloon - occluded retrograde transvenous obliteration ( B - RTO ) in
patients with
hemorrhage from
gastric fundal varices . -
pubmed
METHODS : Thirty - four consecutive
patients with
bleeding from
gastric varices who were treated with B - RTO were enrolled in this study between December 1994 and September 2005 ( urgent cases , n = 12 ; elective cases , n = 22 ) . -
pubmed
RESULTS : Complete obliteration was achieved in 31 of 34 ( 91 % )
patients with an acute
bleeding episode . -
pubmed
Gastric varices disappeared in all
patients with complete obliteration during the treatment . -
pubmed
Variceal
rebleeding from
esophageal varices occurred in three
patients . -
pubmed
The
patients with worsening
esophageal varices were successfully treated with an endoscopic procedure . -
pubmed
MATERIAL AND METHODS : We reviewed the records of all
PC patients who were potential candidates for a surgical staging procedure prior to treatment with intent to cure at Skejby Sygehus , Denmark between 1996 and 2004 . -
pubmed
RESULTS : A total of 50
patients ( 22 % ) had lymph node
metastases ( pN1 ) and only 12 of these cases ( 24 % ) were detected by imaging . -
pubmed
The 12
patients identified by imaging had clinically advanced and pathologically aggressive
cancers . -
pubmed
Forty percent of
patients with
end stage renal disease wait more than 2 years for renal transplant . -
pubmed
The reconstructed kidney was allotransplanted to a 62 - year - old
man with
end stage renal disease . -
pubmed
The cognitive performance of a group of 24
patients recovering from
TBI ( with a mean Glasgow Coma Scale score in the severely impaired range ) was measured at 2 and 5 months postinjury . -
pubmed
To explain this mechanism , an experimental study has quantified that the bone marrow cell transplantation decreases the number of inflammatory cells and reduces the
fibrosis area in chagasic
mice . -
pubmed
METHODS : Retrospective analyses were performed on eight
patients with
metopic synostosis treated at St. Mary 's Hospital ( Seoul ) during 2002 - 2006 . -
pubmed
Two
patients had concomitant
bicoronal synostosis requiring coronal suture resection with anterior two - thirds calvarial reconstruction . -
pubmed
SUBJECTS :
Individuals with long - standing
hypopigmented cervicofacial scars . -
pubmed
Outcome measures included observer and
patient subjective assessment of the
scar , and objective evaluation of the
erythema and melanin content of the
scar and the surrounding skin . -
pubmed
METHODS : The case notes of 107
diabetics with
proliferative retinopathy undergoing indirect PRP were reviewed retrospectively , and compared with the UK National
Diabetic Retinopathy Laser Treatment Audit . -
pubmed
One
patient with underlying
neurotrophic keratopathy developed a persistent epithelial defect . -
pubmed
PATIENTS : Nineteen
patients with gastric superficial lesions ( 15 - 30 mm ) , with high - grade ( n = 15 ) or low - grade ( n = 4 ) noninvasive
epithelial neoplasias , in the antrum ( n = 12 ) , incisura angularis ( n = 2 ) , body ( n = 3 ) , and cardia ( n = 2 ) . -
pubmed
In this review , the pathophysiology of smoke
inhalation injury , along with the characteristics found in clinical settings , common
animal models , current treatment methods and future potential therapeutics are discussed . -
pubmed
Using the
Phaseolus vulgaris system , we have addressed the questions concerning accumulation of sublimons , the role of recombination in their maintenance and selective amplification during
SSS . -
pubmed
Providing an acceptable quality of life for
patients after reconstruction of
mandibular segmental defects is challenging because the surgical techniques available have limitations . -
pubmed
Four
patients with severe
mandibular osteoradionecrosis underwent a two - stage reconstruction . -
pubmed
We describe one
patient with conversion
dumbness and another with conversion
paraplegia . -
pubmed
Bet 1 :
steroids for
patients with
vestibular neuronitis . -
pubmed
Genetic analyses of
Drosophila CNS neoplasia ,
mouse glioma models , and
human glioma tissues have revealed a link between increased NSC self - renewal and brain
tumorigenesis . -
pubmed
Furthermore , data from various
rodent models of
malignant brain tumors have provided compelling evidence that multipotent NSCs and lineage - restricted neural progenitor cells ( NPCs ) could be the cell origin of
brain tumors . -
pubmed
OBJECTIVE : In
cats , spike - wave ( SW )
seizures have been observed to emerge from cortical slow oscillations ( CSOs ) and spindles in sleep . -
pubmed
We examined a
patient 's generalized SW
seizures that appeared to emerge from CSOs in sleep . -
pubmed
SIGNIFICANCE : The correlation of SW
seizures with CSOs in
animal studies may be observed in
humans as well , providing clues to the pathology of arousal regulation in some cases of
nocturnal epilepsy . -
pubmed
The study we conducted showed that the ME is present in geriatric
patients with
MCI ; the influence on spatial - temporal abilities remains constant in time if the stimulation is maintained . -
pubmed
Subthalamic lesion in the
primate . -
pubmed
Relationship between serum acute - phase proteins and high disease activity in
patients with
rheumatoid arthritis . -
pubmed
PURPOSE : The aim of this study was to assess the relationship between serum acute - phase proteins and high disease activity evaluated by activity score ( DAS28 ) in
patients with
rheumatoid arthritis . -
pubmed
MATERIAL / METHODS : Studies were carried out on 27
females with
RA and 32 control
women . -
pubmed
RESULTS : The serum levels of acute - phase proteins changed in
RA patients . -
pubmed
Of the 129
patients assessed , the rate of adult
ADHD was 27.9 % . -
pubmed
In response to
injury , the function of the adult
mammalian central nervous system ( CNS ) is repaired by angiogenesis and neurogenesis . -
pubmed
PATIENTS AND METHODS : Thirty BPH
patients complaining of
erectile dysfunction along with moderate - to - severe
lower urinary tract symptoms (
LUTS ) who underwent transurethral resection of the prostate ( TURP ) were enrolled in the present study . -
pubmed
OBJECTIVE : To simulate and assess the clinical effect of intracoronary infusion of bone marrow mononuclear cells or peripheral endothelial progenitor cells on
myocardial reperfusion injury in mini -
swine model . -
pubmed
METHODS : Twenty - three mini -
swine with
myocardial reperfusion injury were used as designed in the study protocol . -
pubmed
Crude extracts of
Agaricus brasiliensis induce apoptosis in
human oral cancer CAL 27 cells through a mitochondria - dependent pathway . -
pubmed
However , the exact anticancer mechanisms of ABM on
human oral cancer cells are still unclear . -
pubmed
Phase II trial of intraperitoneal
cisplatin combined with intravenous
paclitaxel in
patients with
ovarian , primary peritoneal and fallopian tube cancer . -
pubmed
: Although only 52 % of
patients were able to complete 6 cycles of
cisplatin - based IP chemotherapy , significant reductions in
cisplatin - related
metabolic toxicity and catheter - related complications were noted . -
pubmed
Here , we use two - photon imaging to monitor the fine structure of inhibitory neurons in
mouse visual cortex after deprivation induced by
retinal lesions . -
pubmed
Recent
animal studies have clarified mechanisms leading to the
ototoxicity induced by these agents , at least in part . -
pubmed
In this review , recent findings from
animal studies regarding the
ototoxicity induced by
aminoglycosides ,
cisplatin , and NSAIDs are summarized . -
pubmed
The in vitro activities of inhibiting
pig platelet aggregation induced by
PAF ,
ADP , and AA , as well as the in vivo anti -
thrombotic activities of inhibiting
rat thrombosis of these aromatized derivatives were generally higher than that of
N -( 1 - methyl - beta - tetrahydrocarboline-3 - carbonyl )- N '-( aminoacid - acyl )- hydrazines . -
pubmed
Analysis and perspective : A randomized , open - label , comparative crossover handling trial between two durable pens in
patients with
type 1 or 2 diabetes mellitus . -
pubmed
Pap smears were prepared from
patients presenting with complaints like
vaginal discharge ,
post - coital bleeding ,
inter - menstrual bleeding ,
dyspareunia , and
pain lower abdomen . -
pubmed
Mean age of the
patients with diagnosis of
LSIL was 32.3 years and for
HSIL , it was 40.5 years . -
pubmed
The mean age of the
patients with invasive
carcinoma was 57 years . -
pubmed
Neutrophils isolated from
AMI patients showed two - fold higher ROS generation compared with cells from healthy donors , especially in the
lucigenin - enhanced luminescence model , which suggests intensive
O2- generation . -
pubmed
Resting electrocardiogram predicts mortality in postmenopausal
women with
coronary heart disease or with risk factors for
coronary heart disease . -
pubmed
RESULTS : During a median follow - up of 5.6 years , 500
women sustained
coronary death . -
pubmed
Semantic priming in remitted
patients with
bipolar disorder . -
pubmed
The present study aimed to investigate semantic priming in
patients with
bipolar disorder (
BD ) . -
pubmed
Severe
SR was encountered in 24 ( 44 % )
patients with
SRs . -
pubmed
The median level of sBT in
children with
SRs ( median , interquartile range ) [ 4.2 mug / l ( 3.6 - 4.9 ) ] was significantly higher than in children with
LLRs [ 3.1 mug / l ( 2.5 - 4.0 ) ] and healthy control subjects [ 2.9 mug / l ( 2.3 - 3.4 ) ] ( P & lt ; 0.001 ) . -
pubmed
Determination of sBT levels may help clinicians to identify patients under risk of severe
SRs and optimal and timely use of therapeutic interventions in
children with
venom allergy . -
pubmed
Human prion diseases : progress in clinical trials . -
pubmed
In the late 1940s , epidemics of antibiotic - resistant
strains of
Staphylococcus aureus began to plague postpartum nurseries in hospitals across the United States . -
pubmed
The exploration of these measures reveals a shift in
infection control policy as hospitals , faced with the failure of antibiotics to slow
S. - pubmed
Showcasing the need for widespread epidemiologic surveillance , ultimately manifesting itself in specialized " hospital epidemiology " training promoted in the 1970s , the challenges faced by hospital nurses in the 1950s prove highly relevant to the continued struggle with
methicillin - resistant
Staphylococcus aureus (
MRSA ) and other resistant
nosocomial infections . -
pubmed
A Pilot Study of
Fluorodeoxyglucose Positron Emission Tomography Findings in
Patients with
Phenylketonuria before and during
Sapropterin Supplementation . -
pubmed
1 ) To evaluate brain
glucose metabolism with
FDG - PET imaging in
phenylketonuria (
PKU )
patients before and 4 months after
sapropterin therapy ; 2 ) to evaluate neurodevelopmental changes , blood
Phe levels and dietary
Phe tolerance before and after
sapropterin therapy ; 3 ) to generate pilot data to assess the feasibility of evaluating brain
glucose metabolism with
FDG - PET imaging and to explore potential trends resulting from the administration of
sapropterin therapy . -
pubmed
METHODS : We enrolled 5
subjects , ranged in age from 22 years to 51 years , with
PKU . -
pubmed
CONCLUSIONS : Further studies with a larger sample size are needed to confirm the above changes in both
sapropterin non - responsive and responsive
PKU patients . -
pubmed
RESULTS : A quantitative PCR ( qPCR ) approach was used to determine the copy numbers of two endogenous double stranded DNA plasmids : pZMO1A ( 1,647 bp ) and pZMO7 ( pZA1003 ; 4,551 bp ) within the NCIMB 11163
strain of
Z. - pubmed
METHODS : Ventriculoarterial coupling was assessed before Fontan completion in 32
patients with
hypoplastic left heart syndrome ( 19 modified Blalock - Taussig and 13 Sano shunts at stage 1 ) . -
pubmed
In particular , 5/16 patients with resistance carried viral
strains with SDRMs to multiple
ARV classes , hence one - third of resistant
strains were multiclass resistant , including non - B
strains . -
pubmed
Metabolic disturbances such as
anorexia nervosa ,
obesity , and
diabetes mellitus have clinically important consequences on
human reproduction . -
pubmed
Both groups engaged similar neural networks during processing of emotional music , and
individuals with
ASD rated emotional music comparable to the group of neurotypical
individuals . -
pubmed
All registered
deaths were
HIV - related . -
pubmed
Of 55 patients with subsequent
HIV - RNA measurements , only 12 of 30 ( 40 % ) patients with
VF achieved virological suppression , compared to 20 of 25 ( 80 % ) patients with VR ( p = 0.003 ) . -
pubmed
UNLABELLED : Development of
temozolomide (
TMZ ) resistance contributes to the poor prognosis for
glioblastoma multiforme (
GBM )
patients . -
pubmed
SGT-53 significantly chemosensitized
TMZ - sensitive
human GBM cell lines (
U87 and
U251 ) , in vitro and in vivo . -
pubmed
METHOD : In an A / B single case experimental design , a
patient completed five daily ideographic measures of
anxiety and
depression across baseline and treatment and the HADS at five time points over time , including 3 - month follow - up . -
pubmed
RESULTS : A total of 761 symptomatic
patients ( 40.1 % with
transient ischemic attack [
TIA ] , 21.3 % with
amaurosis fugax , and 38.6 % with
ischemic stroke ) were included , with an overall peri - operative
stroke and
death rate of 3.3 % . -
pubmed
Given the fact that ruptured plaques with neurological symptoms carry the highest risk of a recurrent
ischemic event in the first 2 days , treating
patients as soon as possible to offer the highest benefit in
stroke prevention is recommended . -
pubmed
BACKGROUND : The prevalence of
human papillomavirus ( HPV ) infection and the distribution of different
HPV genotypes vary greatly within different geographical and ethnic populations , especially in Asia . -
pubmed
The
HPV infection data based on regional population are extremely important for researchers to develop new efficient
HPV screening assays and estimate the effect of vaccines on preventing from
cervical cancer . -
pubmed
The top 6
HPV genotypes were
HPV16 ( 1.5 % ) ,
HPV52 ( 1.2 % ) ,
HPV58 ( 1.0 % ) ,
HPV18 ( 0.7 % ) ,
HPV45 ( 0.5 % ) , and
HPV6 ( 0.5 % ) , accounting for 69.7 % of all detected
HPV infection types . -
pubmed
Infection with single genotype
HPV ( 6.2 % in all ; 85.7 % in HPV - positive women ) was more frequent than
infection with multiple
HPV ( 1.0 % and 14.3 % respectively ) . -
pubmed
In this population ,
HPV infection prevalence was 7.3 % , and genotypes
HPV16 ,
HPV52 , and
HPV58 showed a relatively high prevalence . -
pubmed
aureus (
MSSA ) accounted for 64.2 % ( 68/106 ) of the
gram - positive infections . -
pubmed
[ Compound K suppresses myeloid - derived suppressor cells in a
mouse model bearing
CT26 colorectal cancer xenograft ] . -
pubmed
CONCLUSION : C - K can suppress the immunosuppresive effect of MDSCs to inhibit
tumor cell proliferation in
mice , which suggests a new strategy of
tumor therapy by targeting MDSCs . -
pubmed
Intrahepatic transplantation of adipose - derived stem cells attenuates the progression of
non - alcoholic fatty liver disease in
rats . -
pubmed
In the present study , adipose tissue - derived stem cells ( ADSCs ) , which were isolated from the adipose tissues of
Sprague - Dawley rats , were transplanted into the liver of high - fat - diet - induced
NAFLD rats via the portal vein to attenuate the disease progression of
NAFLD . -
pubmed
METHODS : We consecutively enrolled 60
ischemic stroke patients newly started on NOAC treatment and obtained blood samples at 6 prespecified time points . -
pubmed
CONCLUSIONS : If anti - Xa test is not available , we propose the use of the CoaguChek POCT to guide thrombolysis decisions after individual risk assessment in
rivaroxaban - treated
patients having
acute ischemic stroke . -
pubmed
In this observational retrospective single centre study , 28
CML patients with
ACAs at diagnosis and during TKI treatment were included . -
pubmed
In this report , we describe the clinical courses of 2 lung transplant
recipients with
systemic sclerosis who experienced severe and prolonged
barium - impaction
ileus after insertion of a percutaneous gastrojejunal feeding tube . -
pubmed
pneumophila
strains were much higher than those in reference non -
L. - pubmed
pneumophila
strains were similar to those in environmental
L. - pubmed
A 33 - year - old
woman presented with an unusual subglottic bulging mass accompanied by prolonged
cough and
wheeze . -
pubmed
The
patient remains well and free of
recurrence or
metastasis . -
pubmed
BACKGROUND : Periacetabular osteotomy is an excellent intervention for
patients at early - stage
osteoarthritis , but surgical education for this technique is more difficult than that for total hip arthroplasty . -
pubmed
Perioperative and
postoperative complications were observed in 14
patients of the
trainee group and 3
patients of the instructor group , which were significantly different ( p = 0.0061 ) . -
pubmed
Higher early adulthood intake of
fruits and
vegetables rich in
alpha carotene was associated with lower risk of premenopausal
breast cancer . -
pubmed
For individual fruits and vegetables , greater consumption of
apple ,
banana , and
grapes during adolescence and
oranges and
kale during early adulthood was significantly associated with a reduced risk of
breast cancer . -
pubmed
OBJECTIVE : To introduce a new
bone defect model based on the anatomical measurement of radius and ulna in
rabbits for offering a standard model for further tissue engineering research . -
pubmed
RESULTS :
Blood vessel injury ( 1
rabbit ) ,
tendon injury ( 2
rabbits ) , postoperative
hematoma ( 1
rabbit ) , and
infection ( 1
rabbit ) occurred in group A ,
postoperative infection ( 1
rabbit ) in group C , and no
postoperative complications in group B ; the complication rate of group A ( 50 % ) was significantly higher than that of groups B ( 0 % ) and C ( 10 % ) ( P<0.05 ) . -
pubmed
OBJECTIVE : To collect and summarize demographic , clinical , laboratory and radiologic characteristics , as well as management and follow - up data , of
patients diagnosed with
ovarian vein thrombosis . -
pubmed
METHODS : A multicenter retrospective review of all
patients diagnosed with
ovarian vein thrombosis between January 2000 and May 2015 at three university hospitals . -
pubmed
Median duration of anticoagulation treatment tended to be longer among
patients with non - pregnancy related
OVT ( 6months [ 3 - 14 ] vs. 3months [ 3 - 6 ] , P=0.1 ) . -
pubmed
Injection of miR-10b mimics into
tumor cell xenografts also promoted xenograft growth in
nude mice . -
pubmed
BACKGROUND : This is a retrospective chart review to evaluate the efficacy of the addition of
vorinostat to
lenalidomide and
dexamethasone in
patients with
multiple myeloma relapsed / refractory to
lenalidomide and
dexamethasone . -
pubmed
CONCLUSION : These observations demonstrate that the addition of
vorinostat to
patients with
lenalidomide- and
dexamethasone - refractory
multiple myeloma was associated with moderate response and was well - tolerated , warranting further assessment in a larger prospective study . -
pubmed
METHODS : This was a retrospective observational cohort study on
patients with
adenocarcinoma of the pancreatobiliary system who underwent diagnostic core needle biopsy or surgical resection at a tertiary referral center . -
pubmed
Among
patients who underwent surgical resection of their primary
tumor with curative intent , the intestinal type showed an adjusted hazard ratio of 0.19 for overall survival ( 95 % confidence interval 0.05 - 0.72 ; p value = 0.014 ) compared to the extrahepatic pancreatobiliary type . -
pubmed
Streptozotocin (
STZ)-induced
type 1 diabetic rats were subjected to
MI / R surgery with or without perioperative administration of
DATS ( 40 mg / kg ) . -
pubmed
However , the link between IGF-1 and the occurrence of
hearing impairment is untested in population - based studies of
humans . -
pubmed
The aims of this study were to determine
carbapenem resistance mechanisms , molecular epidemiological relationship , clinical impact , and patient outcome of
carbapenem - resistant
Pseudomonas aeruginosa ( CRPA )
infections . -
pubmed
The population included 26
patients with
pseudotumors diagnosed by two radiologists using the method described by Matthies et al . -
pubmed
The f element represents an instance of bacteria - to - animal HGT that has occurred so recently that it was possible to infer the donor ( feminizing Wolbachia closely related to the wVulC Wolbachia
strain of
A. - pubmed
We describe a case involving a 61 - year - old
woman who was suffering from
COA with a concomitant
arch aneurysm and
coronary artery disease . -
pubmed
Dr Jaffe summarizes these alternatives ,
patient selection , success rates , and posttreatment
recurrence . -
pubmed
A 32 - year - old
man , born out of non - consanguineous union , presented with generalised
tonic - clonic seizures and
myoclonus since 17 years of age . -
pubmed
Lower urinary tract autonomic dysfunction evaluation in
spinal cord injury patients : an applied example . -
pubmed
Large strongyles can cause
death of
horses while cyathostomins ( small strongyles ) have shown increased resistance to anthelmintics worldwide . -
pubmed
Clinical Impact of 5 Years of Liraglutide Treatment on Cardiovascular Risk Factors in
Patients with
Type 2 Diabetes Mellitus in a Real - Life Setting in Italy : An Observational Study . -
pubmed
RESULTS : Overall , 103
patients ( age 59.0 + - 7.9 years ,
diabetes duration 10.4 + - 6.8 years ) were involved in the study . -
pubmed
Brain abscess and
bronchopneumonia caused by
Acinetobacter baumannii in a 2 - year - old female
sheep . -
pubmed
PURPOSE OF REVIEW : The leading cause of
death in both
chronic kidney disease (
CKD ) and renal transplant
patients is cardiovascular events . -
pubmed
PTx -
DM has been associated with a negative impact on
patient and graft outcomes and survival . -
pubmed
RECENT FINDINGS :
Individuals who develop
PTx -
DM are usually prone to this condition prior to and/or after developing
CKD . -
pubmed
Severe
vemurafenib - induced
photosensitivity in a 6 - year - old
boy . -
pubmed
While
photosensitivity has been well described as one of these manifestations , we report a case of a 6 - year - old
boy on
vemurafenib who developed a severe blistering
sunburn after only two 30 - minute episodes of sun exposure . -
pubmed
Effectiveness of
influenza and
pneumococcal polysaccharide vaccines against
influenza - related outcomes including
pneumonia and acute exacerbation of
cardiopulmonary diseases : Analysis by dominant viral subtype and vaccine matching . -
pubmed
RESULTS : Among 2,119 enrolled cases , 1,302 ( 61.4 % ) and 871 ( 41.1 % ) received the
influenza vaccine and 23 - valent
pneumococcal polysaccharide vaccine ( PPV23 ) , respectively . -
pubmed
During an A / H3N2 - dominant season with poor
influenza vaccine effectiveness ( 2014 - 2015 season ) , neither the
influenza vaccine nor
PPV23 showed significant effectiveness against
pneumonia or acute exacerbation of
cardiopulmonary diseases . -
pubmed
We developed a multiplex PCR and multi - color fluorescent in situ hybridization ( m - FISH ) protocols for simultaneous detection of
CD - associated pathogens including
Mycobacterium avium subspecies paratuberculosis ( MAP ) ,
Klebsiella pneumoniae , and adherent - invasive
Escherichia coli strain LF82 . -
pubmed
LONG - TERM OUTCOMES AND PROGNOSTIC FACTORS IN
PATIENTS WITH
DIFFERENTIATED THYROID CARCINOMA AND BONE
METASTASES . -
pubmed
Objective : This institutional study sought to retrospectively evaluate
disease progression and survival of
patients with
differentiated thyroid cancer (
DTC ) and
bone metastases (
BM ) and to investigate variables predictive of better long - term outcomes . -
pubmed
Methods : The Rabin Medical Center Thyroid Cancer Registry was searched for
patients with
bone - metastatic DTC . -
pubmed
Variables including a
patient 's gender and age , pathology of the
thyroid tumor , and characteristics of
BM were retrieved and analyzed in association with
disease progression and mortality . -
pubmed
Histopathology yielded papillary and follicular
DTC in 40.6 % and 32.8 % of
patients , respectively , and poorly / intermediately differentiated
carcinoma in 26.6 % . -
pubmed
Nineteen
patients ( 29.7 % ) presented with multiple - site BM , of whom 15 ( 78.9 % ) had
spinal metastases . -
pubmed
Conclusions : Selected
patients with bone - metastatic
DTC may achieve fair long - term outcomes . -
pubmed
This study included 113
patients with a confirmed diagnosis of
type-2 DM . -
pubmed
Among them , 18
patients did not have
diabetic retinopathy (
DR ) , 71 had
non - proliferative DR (
NPDR ) , and 24 had
proliferative DR (
PDR ) . -
pubmed
We suggest prompt ophthalmic evaluation in
patients with
systemic arteriosclerosis . -
pubmed
RESULTS : Among 1938
patients ( mean age 70 + - 11 , 48 % female ) with
ASCVD , the percentage on high - intensity statin therapy significantly increased over time : 24 % in 2013 , 34 % 2014 , 42 % 2015 , and 49 % 2016 ( P & lt ; .0001 ) . -
pubmed
Materials and methods : This case - control study included 112
patients with "
stroke of undetermined etiology " and 160 controls . -
pubmed
Open - ended responses were widespread and often incorrect , specifically with regard to the
human papillomavirus vaccine and routine testing for
sexually transmitted infections . -
pubmed
MATERIALS AND METHODS : Records of
patients with
VKC , who visited our tertiary centre from 1992 and 2009 , were reviewed and those with
steroid - induced
glaucoma were included in the study . -
pubmed
RESULTS : Of the 4062
VKC subjects , 91 ( 157 eyes ) had
steroid - induced
glaucoma (
SIG ) , showing a prevalence of 2.24 % . -
pubmed
Direct immunofluorescence is of limited utility in
patients with low clinical suspicion for an oral
autoimmune bullous disorder . -
pubmed
CONCLUSIONS : In
patients with a low clinical suspicion for an oral
autoimmune bullous disorder , it is reasonable and more cost - effective to evaluate the lesion with routine histology alone . -
pubmed
OBJECTIVE : The aim of the article is to present the clinical observation of a successfully treated giant
aneurysm of the pericallosal artery in a 58 - year - old
man , and also analyze the publications on distal
cerebral aneurysms . -
pubmed
MATERIAL AND METHODS : The data of a
patient hospitalized with a suspected
tumor of the left brain hemisphere spreading to the left lateral ventricle is presented . -
pubmed
The
patient underwent
aneurysm treping - cliping with dissection of the
aneurysm sac . -
pubmed
Biofeedback fixation training method for improving eccentric vision in
patients with
loss of foveal function secondary to different
maculopathies . -
pubmed
METHODS : Sixty - seven consecutive
patients with
bilateral central vision loss , poor FS and visual acuity ( VA ) lower than 0.3 LogMAR were recruited for BFT with microperimeter . -
pubmed
aureus that result in
human infection . -
pubmed
Physical exercise attenuates cognitive decline and reduces behavioural problems in
people with
mild cognitive impairment and
dementia : a systematic review . -
pubmed
QUESTIONS : What is the effect of physical exercise on cognitive decline and behavioural problems in
people with
mild cognitive impairment (
MCI ) or
dementia ? -
pubmed
PARTICIPANTS :
People with
MCI or
dementia as their primary diagnosis . -
pubmed
CONCLUSION : Physical exercise can reduce global cognitive decline and lessen behavioural problems in
people with
MCI or
dementia . -
pubmed
Chemotherapy options versus " novel " therapies : how should we treat
patients with
malignant pleural mesothelioma . -
pubmed
Today there are several options for the treatment of
patients with
malignant pleural mesothelioma (
MPM ) . -
pubmed
Triazolam - induced
Mania in a
Patient with
Bipolar I Disorder Following a Dental Procedure . -
pubmed
Effects of high fat diet - induced
obesity on
vitamin D metabolism and tissue distribution in
vitamin D deficient or supplemented
mice . -
pubmed
Background :
Vitamin D deficiency has been often observed in
obese persons . -
pubmed
Data was extracted for type of radiotherapy , number of
patients , type of
PEG - hydrogel used , mean prostate - rectum separation , rectal dosimetry , acute and late
GI toxicity , procedure - related complications and the technique used for hydrogel insertion . -
pubmed
Improvement Effect of
5 - Aminolevulinic Acid on
Hyperlipidemia in Miniature Schnauzer
Dogs : An Open Study in 5 Cases of One Pedigree . -
pubmed
This is the first study to examine the long - term effect of
5 - aminolevulinic acid mainly on serum lipoproteins in
dogs with
hyperlipidemia . -
pubmed
Cryptococcus neoformans is an opportunistic fungal pathogen , which is a frequent cause of a life - threatening
meningitis in immunocompromised individuals . -
pubmed
The new assay was used to evaluate
SARS - CoV-2 antibodies in serum from individuals with a broad range of
COVID-19 symptoms , including intensive care unit ( ICU ) patients , health care workers ( HCWs ) , and convalescent plasma donors . -
pubmed
Menthol cigarette use in
substance use disorder treatment before and after implementation of a county - wide flavoured
tobacco ban . -
pubmed
INTRODUCTION : This study examined the impact of a San Francisco City and County ban on all flavoured
tobacco products , including
menthol cigarettes , among clients in residential
substance use disorder (
SUD ) treatment . -
pubmed
Notably ,
Radium-4 TCR + T cells also significantly reduced
tumor growth and improved survival in a xenograft
mouse model . -
pubmed
Early and accurate detection of
breast cancer plays an important role in improving the survival rates of
patients . -
pubmed
Chaetomium globosum Kunze is recognized as a potential biocontrol fungus against
spot blotch of
wheat caused by
Bipolaris sorokiniana . -
pubmed
globosum
strain Cg2 during interaction with
B. - pubmed
Venous Thrombosis and Thrombocyte Activity in
Zebrafish Models of Quantitative and Qualitative
Fibrinogen Disorders . -
pubmed
Venous thrombosis occurs in
patients with quantitative and qualitative
fibrinogen disorders . -
pubmed
Injury - induced thrombosis in
zebrafish larvae has been used to model
human coagulopathies . -
pubmed
We aimed to determine whether
zebrafish models of
afibrinogenemia and
dysfibrinogenemia have different
thrombotic phenotypes . -
pubmed
Peanut smut caused by
Thecaphora frezii is a severe
fungal disease currently endemic to Argentina and Brazil . -
pubmed
Linkage of
chloroquine resistance in
Plasmodium berghei to
infection of immature erythrocytes of
mice . -
pubmed
Problem areas both in staging and in general management of
patients with
Hodgkin ' s disease are emphasized . -
pubmed
In ultrathin sections and negatively stained isolates from protoplasts of a
strain of
Saccharomyces cerevisiae showing abnormal morphology and degeneration phenomena the presence of virus - like particles within the cells could be demonstrated . -
pubmed
The connective tissue from Tenon 's capsule of 7
patients who underwent surgery for
retinal detachment was studied ultrastructurally . -
pubmed
The Tenon capsules of 6
children and of 2 aged
patients without
retinal problems were used as controls . -
pubmed
In the aged
patients with
retinal detachment , the collagen fibrils showed marked variation of size and also abnormalities of shape in 4 out of 5 cases . -
pubmed
Effects of endotoxic
shock on diaphragmatic function in mechanically ventilated
rats . -
pubmed
Diaphragmatic function was investigated in mechanically ventilated
rats during
endotoxic shock ( group E , n = 18 ) and after saline solution injection ( group C , n = 8) . -
pubmed
Rearrangements of the T - cell receptor ( TCR ) delta locus are observed in the majority of
human B - cell precursor
acute lymphoblastic leukemias (
ALL ) with a striking predominance of V delta 2(D)D delta 3 recombinations in common
ALL (
cALL ) patients . -
pubmed
Diuretics and arteriolar resistance and arterial compliance in
human hypertension . -
pubmed
Survival of
heart failure patients with preserved versus impaired systolic function : the prognostic implication of blood pressure . -
pubmed
The impact of impaired versus preserved systolic function on survival of
patients with
heart failure was investigated in 78
patients with decompensated
heart failure . -
pubmed
We conclude that the prognosis of
patients with
heart failure and preserved systolic function is more favorable than that of those with impaired function , and that blood pressure may have a differential prognostic meaning in the two groups . -
pubmed
Tumor - bearing
rats re - enter an active growth phase and double their
body weight over age - matched controls 8 weeks after introduction of the
tumor . -
pubmed
Atrial myocytes from
tumor - bearing
animals showed a 3 - fold increase in the density of T - type
Ca2 + current compared with cells from control
animals , although the voltage dependency of activation and inactivation of T - type current was not altered . -
pubmed
Effect of
acarbose on
carbohydrate and lipid metabolism in
NIDDM patients poorly controlled by
sulfonylureas . -
pubmed
The ability of
acarbose to lower plasma
glucose concentration was studied in 12
patients with
non - insulin - dependent diabetes mellitus (
NIDDM ) who were poorly controlled by diet plus
sulfonylurea drugs . -
pubmed
The addition of
acarbose to
patients with
NIDDM not well controlled by
sulfonylureas appears to have significant clinical benefit . -
pubmed
No signs of damage to the cell membrane integrity , neither electrical ( appearance of a leakage current ) nor morphological ( surface
blebs , loss of striation pattern and of rodlike shape in the isolated myocytes ) , accompanied the effects observed on ionic currents and action potential activity , supporting the hypothesis of a selective
cardiotoxic action of
B. - pubmed
Tobacco consumption was positively associated with
gastric cancer in males ( odds ratio as the approximate relative risk = 2.8 ) , whereas
alcohol consumption was not . -
pubmed
Monocyte - derived macrophages ( M phi ) from
cancer patients injected with low doses of
Neocarzinostatin (
NCS , 500 units / day , three times a week ) 12 times produced significantly more
superoxide (
O2 - ) than controls . -
pubmed
[ Frequency of
recurrence after 3 days of therapy of the first
infection of the lower urinary tract segment in
children ] . -
pubmed
Sultamicillin (
SBTPC ) fine granules were given to 15
patients with
respiratory tract infections at a dose of 375 mg 3 times a day . -
pubmed
Positron emission tomography ( PET ) offers a unique opportunity for studying the cerebral biochemistry of
cocaine abuse in
humans . -
pubmed
We present the clinical manifestations and details of treatment and outcome for eight
patients with
squamous cell cancer arising in the thyroid gland , which is a rare entity . -
pubmed
All
patients had advanced disease , with primary
tumors invading adjacent structures ( the trachea , esophagus , and major vessels ) . -
pubmed
In two
patients , pulmonary
metastases were also present . -
pubmed
Two
patients remained free of disease at last follow - up more than 4 years after gross total
tumor resection and radical radiotherapy and were presumably cured . -
pubmed
Patients with unresectable
tumors are best managed by supportive measures only unless a truly effective chemotherapeutic regimen is developed for
squamous cell cancer of the head and neck . -
pubmed
To determine the natural history of
myocardial infarction (
MI ) in the absence of angiographically significant ( no lesion greater than or equal to 50 % diameter stenosis ) fixed
coronary artery disease (
CAD ) , clinical and angiographic data and late outcome were studied in 43 such
patients . -
pubmed
Mild fixed
CAD , present in 38
patients ( 88 % ) , was more frequent in the artery supplying the
MI zone ( p less than 0.01 ) . -
pubmed
Filling defects or serial angiographic resolution of obstruction in the artery supplying the
MI zone were present in 14
patients ( 33 % ) . -
pubmed
At late follow - up , 14 major cardiac events occurred in 9
patients , including revascularization in 3 , recurrent
MI in 6 and
cardiac death in 5 . -
pubmed
Of 35
patients undergoing catheterization within 1 year of the index
MI , cumulative risk of a major cardiac event was 9 + /- 4 , 12 + /- 5 and 20 + /- 7 % at 3 , 19 and 37 months , respectively . -
pubmed
[ Aggravating action of
oxygen in light
injury to the retina in the white
rat ] . -
pubmed
Germinated spores and vegetative cells both showed two phases of elimination from the
hamster cecum -- an initial phase of rapid
death that was not affected by antibiotic treatment followed by a phase of complete inhibition of multiplication . -
pubmed
The resistivities of a Swarm
murine basement membrane
sarcoma and also surrounding tissue in BALB / c
mice were determined . -
pubmed
Methisazone increased the mortality from
ectromelia in adjuvant - treated
animals . -
pubmed
Interactions of anti - inflammatory drugs in carrageenan - induced
foot edema of the
rat . -
pubmed
During studies of the metabolism of
disodium aurothiomalate in
patients with
rheumatoid arthritis we have found that its pharmaceutical preparation . -
pubmed
[ Clinical pharmacokinetics of antihypertensive drugs and the treatment of
hypertension with special reference to
children ] . -
pubmed
Pemphigus and pemphigoid in
dog and
man : comparative aspects . -
pubmed
A review of
canine pemphigus vulgaris ,
pemphigus vegetans ,
pemphigus foliaceus ,
pemphigus erythematosus , and
bullous pemphigoid shows them to share many clinicopathologic similarities with their
human counterparts . -
pubmed
Because of their numerous analogies in clinical presentations , histopathologic and immunopathologic findings , and therapeutic results ,
canine and
human pemphigus and
pemphigoid may represent a valuable area for comparative dermatologic research . -
pubmed
A 63 - year - old
female on long - term , high - dose
tamoxifen treatment for metastatic
breast cancer developed bilateral
intraretinal refractile opacities , lesions at the level of the retinal pigment epithelium , and
cystoid macular oedema . -
pubmed
In al five
patients the
safflower oil was effective in remitting the symptoms of
neurotoxicity . -
pubmed
Safflower oil was also effective in a
patient with
familial tremor . -
pubmed
False positive latex agglutination test with
Neisseria meningitidis ACYW135 in a
patient with
intracranial dermoid tumor . -
pubmed
Apparent outbreaks of
Clostridium difficile - associated diarrhea in
horses in a veterinary medical teaching hospital . -
pubmed
Intestinal colonization with toxigenic
strains of
Clostridium difficile was documented in 9 of 10
horses with acute onset
diarrhea in a veterinary medical teaching hospital , whereas a similar isolate was detected in only 1 of 23 other horses without
diarrhea in the hospital . -
pubmed
One
horse with
diarrhea was infected simultaneously with both
C. - pubmed
difficile isolates were detected in the feces of the 9 affected
horses at the time of the outbreak of
diarrhea . -
pubmed
[
Melanoma in
children : a case ] . -
pubmed
INTRODUCTION :
Melanoma is rare in
children . -
pubmed
DISCUSSION : The diagnosis of
melanoma is difficult in
children and is usually mistaken . -
pubmed
All
patients were assessed for their age , preoperative bladder capacity , preoperative postvoid residual , operative time , estimated blood loss , length of hospital stay , postoperative analgesia requirement , time required to resume a normal voiding pattern , complications , and
recurrence rate of the SUI . -
pubmed
CONCLUSIONS : Retropubic LBNS is a technically feasible surgical procedure for
patients with anatomic
SUI . -
pubmed
Variants of
hepatitis B virus (
HBV ) ,
hepatitis C virus (
HCV ) and of the
hepatitis Delta virus (
HDV ) have been identified in patients both with acute and
chronic infections . -
pubmed
The exact contribution , however , of specific mutations to the pathogenesis and natural course of
HBV ,
HCV or
HDV infection , including the development of
hepatocellular carcinoma , remains to be established . -
pubmed
To examine whether structural changes in hepatocytes and/or sinusoidal areas contribute to the portal
hypertensive state in
non - alcoholic cirrhosis , a new method of morphometric analysis using a computer - aided color image analyzer was performed in 16
patients with
non - alcoholic cirrhosis , which allowed quantitative evaluation of various morphometric parameters of sinusoids and hepatocytes . -
pubmed
Nasal
mupirocin ointment decreases the incidence of
Staphylococcus aureus bacteraemias in haemodialysis
patients . -
pubmed
aureus
bacteraemia in a haemodialysis unit was studied over 2 years ( 167.75 patient - years of follow - up ) during which nasal
calcium mupirocin was used to eradicate nasal
S. - pubmed
Currently , the high level of operability of
patients with endometrial
carcinoma makes this staging system a viable one , which will provide information about the need for additional treatment . -
pubmed
FDG - PET in differentiating
lymphoma from
nonmalignant central nervous system lesions in
patients with
AIDS . -
pubmed
We studied 11
individuals with
AIDS and central nervous system ( CNS ) lesions with
18F - fluoro-2 - deoxyglucose (
FDG ) and positron emission tomography ( PET ) . -
pubmed
FDG - PET may be useful in the management of
AIDS patients with
CNS lesions since high
FDG uptake most likely represents a malignant process which should be biopsied for confirmation rather than treated presumptively as infectious . -
pubmed
Partial kidney transplantation : a successful kidney transplantation in a
child with severe
cardiac failure by surgical mass reduction of an adult donor kidney . -
pubmed
Effects of
diencephalic lesions on approach responses and color preferences in
quail . -
pubmed
This empirical approach does not require a strong mathematical background and offers a relatively simple method of predicting the kinetics of anti -
cancer drugs in
patients from pre - clinical animal data . -
pubmed
beta - Alanine protects against
taurine and
NaCl -- induced
hypernatremia in the
rat . -
pubmed
Rats drinking a combination of
taurine and hypertonic saline solution rapidly develop
hypernatremia , but
rats drinking either solution alone do not . -
pubmed
This transformation system will enable us to breed commercial
strains of
P. - pubmed
Validation study of a central venous pressure - based protocol for the management of neurosurgical
patients with
hyponatremia and natriuresis . -
pubmed
OBJECTIVE : We had previously suggested a protocol for the management of neurosurgical
patients with
hyponatremia and natriuresis that was based on their volume status as determined by actual blood volume measurements . -
pubmed
All
patients in that study were found to be
hypovolemic or normovolemic and responded , within 72 hours , to salt and fluid replacement . -
pubmed
In the present study , the validity of that protocol was tested using central venous pressure as the sole measure of volume status of
patients with
hyponatremia and natriuresis . -
pubmed
METHOD : Twenty - five consecutive
patients ( 26 cases ) who fulfilled the inclusion criteria typically used to diagnose the
syndrome of inappropriate secretion of antidiuretic hormone were included in the study . -
pubmed
Central venous pressure was used to classify
patients as
hypovolemic ( & lt ; 5 cm of water ) , normovolemic ( 6 - 10 cm of water ) , or
hypervolemic ( & gt ; 11 cm of water ) . -
pubmed
Hypovolemic patients were given fluids ( 50 ml / kg / d ) and salt ( 12 g / d ) . -
pubmed
In addition ,
patients with
anemia ( hematocrit , & lt ; 27 % ) were administered whole blood . -
pubmed
No
patient was
hypervolemic . -
pubmed
CONCLUSION :
Hyponatremia with natriuresis in the neurosurgical setting responds to salt and fluid replacement guided by the
patients ' volume status as determined by the central venous pressure . -
pubmed
Compared to the outbred
Wistar rat strain , the Fawn - hooded
rat strain has several characteristics which suggest that the Fawn - hooded
strain is
hyperaroused . -
pubmed
Fawn - hooded
rats exhibit more freezing behavior in response to stress , have an increased preference for
alcohol , develop adult onset
hypertension , and have elevated urinary
catecholamine levels . -
pubmed
Finally , adrenal weights were significantly reduced in the Fawn - hooded
rats while basal
corticosterone levels were similar in the two
strains , which suggests central hypoactivity of the hypothalamic - pituitary - adrenal axis in Fawn - hooded
rats compared to
Wistar rats . -
pubmed
Helicobacter pylori infection is the most frequent
infection in
humans . -
pubmed
Compared with younger patients , elderly
patients with
PSGN tend to have a high incidence of
renal function impairment and
anuria or prolonged
oliguria . -
pubmed
Efficacy of low - dose
isotretinoin in
patients with
treatment - resistant rosacea . -
pubmed
We report here the characterization of the in vitro ( in the presence of 6000
IU interleukin 2 ) expanded tumor - infiltrating lymphocyte ( TIL ) T - cell line PM2 - B2 derived from a
patient with rapidly progressing and therapy - resistant
head and neck melanoma . -
pubmed
During
infection with
vesicular stomatitis virus (
VSV ) , host - cell mRNA synthesis is inhibited due to shut off of host - cell transcription . -
pubmed
Furthermore , the correlation between brain structure and CMRO2 suggests that monitoring CMRO2 during the operation may be an outstanding way to investigate new strategies for neuroprotection designed to reduce
cerebral damage in
children undergoing correction of
congenital cardiac defects . -
pubmed
Inhaled
nitric oxide (
NO ) was administered to 5 consecutive
children with life - threatening
status asthmaticus who required mechanical ventilation and did not respond to maximal medical management . -
pubmed
A recommendation is included how to advise
patients with
Parkinson ' s disease treated with a
dopamine agonist regarding the ability to drive . -
pubmed
INTRODUCTION : What causes
meningococcial diseases (
MD ) is a Gramm - negative diplococcus
Neisseria meningitidis (
meningococcus ) . -
pubmed
Substance P in rectal mucosa of
children with
chronic constipation . -
pubmed
Substance P content was determined by radioimmunoassay in rectal mucosa of 17
children with
idiopathic constipation and 9 with normal bowel movements who were used as controls . -
pubmed
Substance P levels in rectal mucosa of
children with
soiling ( 11/17 ) did not differ from those of chronically constipated
children without soiling ( 46.0 + /- 16 vs. 50.5 + /- 19 pg / mg net weight ) . -
pubmed
In
children with
constipation ,
substance P levels did not correlate either with age or duration of symptoms . -
pubmed
RESULTS : Most of the
patients were in terminal phase ( 19 ) , the fundamental cause ( 17 cases ) that justified the use of the subcutaneous tract was the difficulty to take drugs by oral tract in the last days of life , attention on
death throes . -
pubmed
The drugs and initial average dose most used were :
morphine 19
patients dose 100 mg/24 h ,
hyoscine butylbromide (
Buscapina ) , 13
patients , 60 mg/24 h ,
haloperidol 12
patients , 4 mg/24 h. The
patients death was the main cause that justified the retirement of the continuous infusion ( 17 people sick ) , happening in its own home . -
pubmed
Apoptosis in young
rats with
adriamycin - induced
cardiomyopathy -- comparison with
pirarubicin , a new
anthracycline derivative . -
pubmed
To investigate whether
pirarubicin has a lower chronic
cardiotoxicity compared with
ADR ,
ADR or
pirarubicin were injected weekly for 8 wk into young
Wister rats via the tail vein . -
pubmed
METHODS : 50 eyes of 50 consecutive
patients with graft
infection after an optical penetrating keratoplasty were included as cases ; 50 eyes of 50
patients with no graft
infection were included as controls . -
pubmed
Adeno - associated virus (
AAV ) is a member of the parvovirus family , is a nonpathogenic virus with a broad host cell range , and does not provoke a significant immune response upon
infection . -
pubmed
We review here recent advances in
AAV vectors used for gene transfer of the
haemophilias . -
pubmed
A case of acquired
haemophilia in a
patient with
lupus is reported . -
pubmed
CASE REPORT : A 30 year - old
woman with
systemic lupus erythematosus developed a right
coxalgia and
ecchymotic skin lesions which were prominent on the right arm and forearm . -
pubmed
We present and discuss the case of a
patient with primitive cerebral localization of
Wegener ' s Granulomatosis in which the diagnosis and the beginning of correct therapy were delayed , in spite of a rising c - ANCA titer , due to a misinterpretation of a bioptic specimen . -
pubmed
UNLABELLED : The variation of capillary filtration rate ( CFR ) and
ankle edema ( AE ) were evaluated in three groups of
patients with
venous hypertension with ambulatory venous pressure & gt ; 42 mmHg and in healthy subjects before and after treatment for four weeks with HR (
Paroven ,
Venoruton ;
0 -( beta - hydroxyethyl )- rutosides ) , a venoactive drug acting on the microcirculation and on capillary permeability . -
pubmed
The decrease in the score in the groups of
patients was correlated with the variation in
edema and CFR . -
pubmed
A new
epothilone ,
10,11 - didehydroepothilone D ( 5 ) , was isolated from a
strain of the heterologous host
Myxococcus xanthus genetically engineered to produce
epothilone D ( 4 ) . -
pubmed
High levels of
HIV-1 replication occur following
perinatal infection and antiretroviral drugs may not fully suppress viral load during the early years of childhood . -
pubmed
Randomized phase III trial of single versus fractionated thoracic radiation in the palliation of
patients with
lung cancer ( NCIC CTG SC.15 ) . -
pubmed
The European Organization for Research and Treatment of
Cancer QLQ - C30 scores showed that
patients receiving five fractions had a greater improvement in scores with respect to
pain ( p = 0.04 ) . -
pubmed
To investigate the
ischaemia / reperfusion phenomenon in skin flaps , we first investigated the vascular anatomy of
murine dorsal skin and then designed a suitable
murine dorsal skin flap model . -
pubmed
Inhibition of cusp and
aortic wall calcification in
ethanol- and
aluminum - treated bioprosthetic heart valves in
sheep : background , mechanisms , and synergism . -
pubmed
Stentless bioprostheses fabricated from GA - fixed
porcine aortic valves pose an important challenge in this regard , as
pathologic calcification can affect not only the bioprosthetic cusps , but also the aortic wall segment . -
pubmed
More specifically , we wanted to see whether or not there was any regular relationship between the differential time trends of the above 3
human neoplasias and their oncogene -
tumor suppressor gene balances . -
pubmed
The integrity of the above findings is discussed in the light of a number of pioneering achievements along the line of the
steroid criminal theory of
carcinogenesis in
humans and in non -
human mammals . -
pubmed
[ Study on the effect of
isonicotinic acid hydrazide and
p - aminosalicylic acid on experimental
tuberculosis in
guinea pigs ] . -
pubmed
[ Considerations on the discrepancies between in vitro sensitivity and clinical results in antibiotic therapy of
infections caused by
Staphylococcus pyogenes aureus ] . -
pubmed
[ Blood circulation and
oxygen consumption by the liver in experimental
cirrhosis in
dogs ] . -
pubmed
Our results have potential application to the assessment of
tumor characteristics in vivo in
human tumors for individualized
cancer therapy . -
pubmed
We describe a 59 - year - old
man with
nephrotic syndrome that was diagnosed as suspected minimal change
nephrotic syndrome by the routine examination of renal tissues at first biopsy , because renal histology showed segmental mild mesangial expansion with argyrophilic staining and partial foot process fusion without any deposition . -
pubmed
Three - dimensional computerized analysis of diadochokinetic movements of
Parkinsonian patients . -
pubmed
The purpose of this study was to investigate the usability of a computerized movement analysis system in
Parkinson ' s disease patients . -
pubmed
MATERIAL AND METHODS : We analysed the effect of
L - dopa in a group of 14
patients with
idiopathic Parkinson ' s disease and compared the results to those of 14 control persons . -
pubmed
A 74 - year - old
woman presented with progressive mental deterioration following a low - grade
fever and
headache . -
pubmed
We experienced a male
patient with
psoriasis and
hypertension whose conditions were treated with
tacalcitol ointment and
thiazide , respectively , resulting in
hypercalciuria and
hypercalcemia . -
pubmed
Thymoma was present in one of the ten
patients . -
pubmed
Compared with a similar historical group of
patients with
MG who underwent transsternal thymectomy , the VATS group was associated with significantly less analgesic requirement and shortened hospital stay . -
pubmed
Effect of artificially induced
hyperthermia on the electrocardiogram of the
dog . -
pubmed
Prognostic value of intratumoral vessel density in
cutaneous mast cell tumors of the
dog . -
pubmed
The biological behaviour of
canine cutaneous mast cell tumours ( MCTs ) is highly variable . -
pubmed
The aim of this study was to investigate whether intratumoral microvessel density ( IMVD ) , as an indicator of angiogenesis , was predictive of biological behaviour in
MCTs of
canine skin , and to relate this parameter to histological grade and other histomorphological features . -
pubmed
The relation of angiogenesis to biological behaviour and histological parameters of
malignancy of
cutaneous MCTs was consistent with previous findings in
human and animal
tumours . -
pubmed
Human rights group accuses Russian government of hampering efforts to tackle HIV /
AIDS . -
pubmed
Dissatisfied with the treatment available , the authors report on the use of a closed , controlled drainage procedure in eight
patients with severe
edema of the lower limbs . -
pubmed
In addition , the
pain experienced by the
patients has been monitored during treatment . -
pubmed
Photobleaching was monitored by fluorescence imaging , and
pain experienced by the
patients was registered by using a visual analogue scale graded from 0 ( no
pain ) to 10 ( unbearable
pain ) . -
pubmed
No significant difference in
pain experienced by the
patients during PDT was observed in varying the fluence rate from 30 to 75 mW cm(-2 ) . -
pubmed
RESULTS : Here we report the construction and characterization of a highly redundant
bacterial artificial chromosome ( BAC ) library constructed from a Norwegian aquaculture
strain male of
Atlantic salmon (
Salmo salar ) . -
pubmed
METHODS : Ninety - one
patients ( 37
tuberculous pleural effusions , 42
malignant pleural effusions of lung cancer and 12 transudates ) were included . -
pubmed
Effects of
raloxifene and low - dose
simvastatin coadministration on plasma lipids in postmenopausal
women with
primary hypercholesterolemia . -
pubmed
Despite the disappointments of recent large scale clinical trials evaluating the efficacy of antioxidants in
cardiovascular disease , many therapeutic agents which have been used successfully in
diabetic subjects at high risk for
cardiovascular disease have a mechanism of action which includes an antioxidant capacity . -
pubmed
A major advantage of this strategy is that it allows one standard cell line to be applied to all
patients and this approach can be extended to the treatment of other
tumour types . -
pubmed
Encapsulated cells were angiographically placed into the
tumour vasculature of 14
patients and followed by systemic low dose
ifosfamide treatment . -
pubmed
Four of the treated
patients showed
tumour regressions after capsule delivery and
ifosfamide treatment in computer - tomography scans . -
pubmed
The other 10
patients showed no further
tumour growth ( i.e. -
pubmed
Axillary
recurrence in
women with a negative sentinel lymph node and no axillary dissection in
breast cancer . -
pubmed
The purpose of this study was to determine the frequency of axillary lymph node
recurrence in
patients who had a negative sentinel lymph node and did not undergo axillary node dissection . -
pubmed
For each
woman with
recurrence , the dates of
recurrence , the site(s ) of
recurrence , and the treatment for
recurrence were recorded . -
pubmed
Only two
patients ( 0.6 % ) had an axillary
recurrence . -
pubmed
Cytotoxicity and transcriptional activation of stress genes in
human liver carcinoma (
HepG2 ) cells exposed to
iprodione . -
pubmed
Experimental studies with
mice have indicated that exposure to
iprodione at dose levels 5 to 15 folds greater than the LOAEL for
liver injury , induces microsomal enzyme activities , hepatocyte proliferation ,
hepatomegaly ,
centrilobular hypertrophy , diffuse
hypertrophy , and an increase in
lauric acid hydroxylation . -
pubmed
Viral
hepatitis B (
HBV ) and C (
HCV ) are a significant cause of morbidity and mortality in patients coinfected with
human immunodeficiency virus (
HIV ) . -
pubmed
In
HBV / HIV coinfection , there is a higher frequency of
HBV replication , and higher rates of
HBV - associated liver disease . -
pubmed
HIV / HBV coinfection is associated with an increased frequency of
hepatotoxicity in patients receiving highly active antiretroviral therapy ( HAART ) , and reactivation of clinical
hepatitis is observed upon stopping
HBV - active anti -
HIV drugs . -
pubmed
In older
humans , infusions of endothelial agonists suggest
endothelial dysfunction , due in part to less
nitric oxide (
NO)- and
prostaglandin ( PG)-mediated vasodilatation , and a shift toward PG - mediated vasoconstriction . -
pubmed
Notably , in young
adults , inhibition of
NO and PGs during exercise decreases exercise
hyperaemia by approximately 20 and approximately 12 % , respectively . -
pubmed
We tested our first hypothesis that in older
humans inhibition of
NO would decrease
hyperaemia , but that inhibition of PGs would increase
hyperaemia by blocking vasoconstrictor PGs . -
pubmed
L - NAME reduced steady - state exercise
hyperaemia by 12 + /- 3 % in older
subjects ( P<0.01 ) , whereas
ketorolac had no net effect on blood flow ( 3 + /- 6 % , P>0.4 ) . -
pubmed
By comparing these results with our previous results in young
adults , we tested our second hypothesis that in older
humans inhibition of
NO or
PGs would have less impact on exercise
hyperaemia due to less vasodilatation from these signals . -
pubmed
Our results suggest that , compared with young adults , in older
humans the relative contribution of
NO to exercise
hyperaemia is reduced approximately 45 % ( 22 + /- 4 versus 12 + /- 3 % ) , but the role of
PG in mediating vasodilatation is lost in ageing
human skeletal muscle . -
pubmed
Lower exercise
hyperaemia in older
humans may be mediated in part by less
NO- and PG - mediated vasodilatation during exercise . -
pubmed
Here , we report a
patient with
RDD who presented a dramatic and sustained response with
cladribine . -
pubmed
Mortality effect of
coronary calcification and
phosphate binder choice in incident hemodialysis
patients . -
pubmed
The risk of
death in hemodialysis
patients treated with
calcium - containing
phosphate binders or
sevelamer is not known . -
pubmed
The greater risk of
death for
patients treated with
calcium - containing
phosphate binders persisted after full multivariable adjustment ( P=0.016 , hazard ratio 3.1 , CI 1.23 - 7.61 ) . -
pubmed
INTRODUCTION : We report two cases of
patients with
prostate cancer who underwent haematological complications from the disease . -
pubmed
CLINICAL CASES :
Diffuse intravascular coagulopathy ( with
thrombopenia ) was observed in two
patients ( 55 and 59 years - old ) diagnosed with
prostate cancer . -
pubmed
In one
patient who had normal prostate at clinical examination ,
thrombopenia with incomplete diffuse intravascular
coagulopathy and biological inflammatory led to diagnosis . -
pubmed
In the other
patient diffuse
intravascular coagulopathy followed introduction of hormonal therapy and lead to the
patient 's
death . -
pubmed
DISCUSSION :
Patients with
metastatic hormone - refractory prostate carcinoma may have life - threatening coagulation complications due to their disease . -
pubmed
When attacked by
HIV , the immune system counteracts
infection with elicitation of HIV - specific antibodies and cytotoxic T lymphocytes . -
pubmed
The role of PCI in the management of
acute coronary syndromes is already well defined , and has increased the preference for an invasive rather than a conservative approach in high - risk
patients without ST elevation and the preference for primary angioplasty rather than thrombolysis in those with ST elevation . -
pubmed
The development and implementation of integrated
coronary syndrome treatment networks will enable
human and material resources to be used efficiently , and will guarantee rapid access to high - quality PCI for those who need it . -
pubmed
At present , there is extensive research into noncoronary interventions , which , in the not too distant future , could provide percutaneous treatment for the many elderly
patients with severe
aortic stenosis who are not currently eligible for surgery . -
pubmed
Topiramate in
patients with episodic
migraine : reducing the risk for chronic forms of
headache . -
pubmed
OBJECTIVE : The aim was to evaluate whether preventive treatment with
topiramate in
patients with
episodic migraine reduces the risk of developing chronic forms of
headache . -
pubmed
METHODS : Pooled data from 3 trials in
patients with episodic
migraine randomized either to treatment with 100 mg
topiramate per day ( n = 384 ) or with placebo ( n = 372 ) were analyzed with regard to the number of
headache days during a prospective 4 - week baseline period and the individual final 4 weeks of each
patient 's treatment during the planned 26 - week double - blind treatment period . -
pubmed
At the end of the study , 8 versus 16
patients fulfilled International
Headache Society criteria of
chronic headache ( odds ratio : 2.11 , P= .082 ) . -
pubmed
Moreover , a significantly lower number of
patients receiving
topiramate treatment reported an increase in
headache days per month by the end of the study when compared to placebo ( 66 vs 88
patients , respectively ; odds ratio : 1.49 , P & lt ; .05 ) . -
pubmed
CONCLUSION : Preventive treatment with
topiramate in
patients with
episodic migraine may reduce the risk of developing chronic forms of
headache . -
pubmed
Ascorbate uptake in normal and
diabetic rat retina and retinal pigment epithelium . -
pubmed
The RPE and retina of
diabetic rats presented lower levels of AA accumulation . -
pubmed
Two of the 10
patients died of
liver failure 5 and 12 years after diagnosis , respectively . -
pubmed
Accordingly , the purpose of this study was to determine if intense normobaric
hypoxic exercise could induce
pulmonary edema in
women . -
pubmed
BACKGROUND : Previous studies have shown that the incidence of
atrial fibrillation after
atrial flutter ablation is approximately 20 % among
patients presenting with typical
atrial flutter and no history of
fibrillation . -
pubmed
OBJECTIVE : The purpose of this study was to provide a more accurate perspective on the long - term risk of
atrial fibrillation in
patients presenting with isolated typical
flutter . -
pubmed
RESULTS : Postablation
atrial fibrillation was identified in 40 ( 50 % ) of 80
patients , and an additional three
patients presented with atypical
atrial flutter , after a mean follow - up of 29.6 + /- 21.7 months . -
pubmed
There was no difference in age , left atrial size ,
hypertension ,
structural heart disease , or
left ventricular dysfunction in
patients who developed
atrial fibrillation compared with those who did not . -
pubmed
CONCLUSION :
Atrial fibrillation occurs in over half of
patients who present with isolated typical
flutter after cavotricuspid isthmus ablation . -
pubmed
Asymptomatic
patients should be screened for recurrent
arrhythmias indefinitely after ablation . -
pubmed
In certain
patients ,
atrial fibrillation and
flutter may be different expressions of the same electrical disease , and eradication of the flutter circuit will not prevent the eventual manifestation of
atrial fibrillation . -
pubmed
Drospirenone /
ethinylestradiol 3mg/20microg ( 24/4 ) is approved in the US for the prevention of pregnancy in
women , for the treatment of the symptoms of
premenstrual dysphoric disorder (
PMDD ) and for the treatment of moderate
acne vulgaris in
women who wish to use an oral contraceptive for contraception . -
pubmed
The backscroll
illusion refers to the apparent motion perceived in the background of a movie image that presents a locomotive object such as a person , an
animal , or a vehicle . -
pubmed
Our hypothesis has implications for the use of drugs or devices in the treatment of
patients with
stress cardiomyopathy . -
pubmed
The effect of oral therapy with
cobaltous chloride on the blood of
patients suffering with
chronic suppurative infection . -
pubmed
These results indicate that reactive astrogliosis and delayed neuronal
death , at least in
rat hippocampus , are sequential pathological events following
MCAO . -
pubmed
Main outcome measure was basal cervical dilatation while the secondary outcome measures were operative blood loss , time duration of surgery ,
patient satisfaction ,
pain perception and adverse effects . -
pubmed
One
patient had lateral
ankle instability at 5 weeks and therefore the therapy continued with prolonged immobilization and then rehabilitation at a slower pace . -
pubmed
We describe here the case of a 39 - year - old
woman with a
cortisol - producing
adrenal adenoma and she presented with
endometrial hyperplasia and
hypertension without the specific characteristics of
Cushing ' s syndrome . -
pubmed
METHODS : Immunohistochemistry was performed on cryosections obtained from five pairs of normal and five pairs of age - matched
diabetic human retinas . -
pubmed
The evaluation of markers of
prostatic inflammation and function of the prostate gland in
patients with
chronic prostatitis . -
pubmed
MATERIALS AND METHODS : The study involved 46
patients with
chronic prostatitis . -
pubmed
trachomatis
prostate infection was detected in 17.4 % of the
patients and all of these men had higher
inflammation parameters and lower
citric acid concentrations . -
pubmed
Extracapsular extension was reported in 13.5 % to 26 % of
patients , and seminal vesicle invasion was reported in 2.9 % to 8.2 % of
patients . -
pubmed
javanica
infection ,
M. - pubmed
Even though the majority of
patients had
glioblastoma , only 5/67 had received adjuvant therapy . -
pubmed
Comparative survival in
patients with postresection recurrent versus newly diagnosed
non - small - cell lung cancer treated with radiotherapy . -
pubmed
PURPOSE : To compare the survival of postresection recurrent vs. newly diagnosed
non - small - cell lung cancer (
NSCLC )
patients treated with radiotherapy or chemoradiotherapy . -
pubmed
METHODS AND MATERIALS : The study population consisted of 661 consecutive
patients with
NSCLC registered in the radiation oncology databases at two medical centers in the United States between 1992 and 2004 . -
pubmed
Of the 661
patients , 54 had postresection recurrent
NSCLC and 607 had newly diagnosed
NSCLC . -
pubmed
CONCLUSION : Our institutional data have shown that
patients with postresection recurrent
NSCLC achieved survival comparable to that of newly diagnosed
NSCLC patients when they were both treated with radiotherapy or chemoradiotherapy . -
pubmed
These findings suggest that
patients with postresection recurrent
NSCLC should be treated as aggressively as those with newly diagnosed disease . -
pubmed
Various
strains of
Atlantic salmon exhibit different levels of susceptibility to
infections with the ectoparasitic monogenean
Gyrodactylus salaris . -
pubmed
OBJECTIVE : This article aims to describe an approach to diagnosis and management based on the location of the
pain , the
patient 's age , and the type of activity being undertaken . -
pubmed
STUDY DESIGN : A multiple - comparative study between normal and
low back pain (
LBP )
patients before and after rehabilitation . -
pubmed
OBJECTIVE : To examine whether there is a change in flexion - relaxation phenomenon in sitting in
LBP patient following a rehabilitation treatment . -
pubmed
Previous study has reported an absence of flexion - relaxation phenomenon in
LBP patients during sitting . -
pubmed
However , it is unknown whether there is a difference in flexion - relaxation phenomenon in sitting in
LBP patients before and after rehabilitation treatment . -
pubmed
METHODS : A total of 20 normal
subjects and 25 chronic
LBP patients who underwent a 12 weeks rehabilitation program were recruited . -
pubmed
Surface electromyography recordings during upright sitting and flexed sitting were taken from the paraspinal muscles ( L3 ) bilaterally from the normal
subjects , and in the
LBP patients before and after the rehabilitation treatment . -
pubmed
Flexion - relaxation phenomenon in sitting , expressed as a ratio between the average surface electromyography activity during upright and flexed sitting , was compared between normal and
patients ; and in
LBP patients before and after rehabilitation . -
pubmed
RESULTS : Flexion - relaxation ratio in sitting in normal
subjects ( Left : 6.83 + /- 3.79 ; Right : 3.45 + /- 2.2 ) presented a significantly higher ( Left : P & lt ; 0.001 ; Right : P & lt ; 0.05 ) value than
LBP patients ( Left : 3.04 + /- 2.36 ; Right : 2.02 + /- 1.49 ) . -
pubmed
An increase in flexion - relaxation ratio in sitting was observed in
LBP patients after rehabilitation ( Left : 4.69 + /- 3.94 , P & lt ; 0.05 ; Right : 3.58 + /- 2.97 , P & lt ; 0.001 ) , together with a significant improvement ( P & lt ; 0.05 ) in subjective tolerance in sitting and standing , abdominal and back muscle endurance , lifting capacity , and range of motion . -
pubmed
CONCLUSION : Flexion - relaxation ratio in sitting has demonstrated its ability to discriminate
LBP patients from normal subjects , and to identify changes in pattern of muscular activity during postural control after rehabilitation . -
pubmed
METHODS : Consecutive series of
patients with primary subfoveal
CNV secondary to pathological
myopia treated with intravitreal
ranibizumab 0.5 mg ( 0.05ml ) were included prospectively in this study . -
pubmed
Hepatitis E virus (
HEV ) has at least 2 distinct epidemiological profiles : ( 1 ) large outbreaks and epidemics in developing countries , usually caused by
HEV genotype 1 , resulting in high morbidity and mortality among pregnant women and young children , and ( 2 ) very few symptomatic cases of
HEV genotype 3 , most cases without symptoms or clear source(s ) of
infection , but frequent seroreactivity in 5%-21 % of asymptomatic persons in developed countries . -
pubmed
CONCLUSIONS : Sacral neuromodulation with the tined lead procedure is a safe and effective treatment for
patients with
overactive bladder symptoms or
urinary retention . -
pubmed
[ Construction of the genetically attenuated bacteria
Bordetella pertussis devoid of dermonecrotic toxin activity and producing modified nontoxic
pertussis toxin form ] . -
pubmed
BACKGROUND :
Infection with
Helicobacter pylori triggers a
chronic gastric inflammation that can progress to
atrophy and
gastric adenocarcinoma . -
pubmed
METHODOLOGY / PRINCIPAL FINDINGS : By using a
mouse model of
infection and gastric biopsies from 29 individuals , we have analyzed macrophage recruitment and polarization during H.
pylori infection by flow cytometry and real - time PCR . -
pubmed
Multiple pathogenic mechanisms by which
HIV and antiretroviral agents lead to
dyslipidemia have been hypothesized , but they are still controversial . -
pubmed
Hutchinson - Gilford progeria syndrome (
HGPS ) is a rare and fatal
human premature ageing disease , characterized by premature
arteriosclerosis and degeneration of vascular smooth muscle cells ( SMCs ) . -
pubmed
Here we report the generation of induced pluripotent stem cells ( iPSCs ) from fibroblasts obtained from
patients with
HGPS . -
pubmed
PURPOSE : To evaluate the ocular
hypotensive efficacy of 0.05 % , 0.1 % and 0.25 %
AR-12286 Ophthalmic Solutions in
patients diagnosed with
ocular hypertension or
glaucoma . -
pubmed
METHODS :
Subjects ( n = 89 ) with
elevated intraocular pressure ( IOP ) were assigned randomly to receive either 1 of 3 concentrations of
AR-12286 or its vehicle . -
pubmed
After once - daily evening dosing ,
hyperemia was seen in less than 10 % of
patients . -
pubmed
CONCLUSIONS :
AR-12286 was well tolerated and provided clinically and statistically significant ocular
hypotensive efficacy in
patients with
ocular hypertension and
glaucoma . -
pubmed
Validation of
doripenem dosing in
patients with
end - stage renal disease receiving hemodialysis . -
pubmed
Systematic studies and clinical trials are difficult to perform in
patients with
cognitive impairment ; recommendations for evaluating and treating
delirium are based primarily upon clinical observation and expert opinion . -
pubmed
The
patient developed
encephalopathy and
liver failure and died despite prompt initiation of
dexamethasone therapy . -
pubmed
The current prognosis of
multiple myeloma patients with
liver failure due to
LCDD is dismal . -
pubmed
In two well designed phase III trials , 14 days ' treatment with
bilastine was associated with a significantly lower area under the effect curve ( AUEC ) for the reflective total symptom score ( TSS ) than placebo in
patients with symptomatic
seasonal allergic rhinitis . -
pubmed
Additionally , reflective nasal symptom scores were significantly lower in
bilastine than placebo recipients in
patients with a history of
seasonal allergic rhinitis who were challenged with grass pollen allergen in a single - centre , phase II study . -
pubmed
In another well designed phase III trial , compared with placebo ,
bilastine was associated with a significantly greater change from baseline to day 28 in the mean reflective daily
urticaria symptom score in
patients with
chronic urticaria . -
pubmed
METHODS : This retrospective paper included 216
patients with
HT , issued from an
iodine - replete area . -
pubmed
RESULTS : The morphologic investigation revealed 9
patients with
DTC and 12 cases with
benign thyroid disease (
BTD).None of the US analyzed characteristics provided sufficient accuracy for the diagnosis of
DTC in cases with
HT . -
pubmed
This review summarizes the epidemiology , associated etiology , diagnosis , management , and outcome of
patients with
SCAD . -
pubmed
CONCLUSIONS : This study confirmed that
varicella vaccine is effective at preventing
chicken pox , with no waning noted over a 14 - year period . -
pubmed
The effect of precipitation on the transmission of
Japanese encephalitis ( JE ) virus in nature : a complex effect on antibody - positive rate to
JE virus in sentinel pigs . -
pubmed
BACKGROUND : Adaptation of
Pseudomonas aeruginosa to different living conditions is accompanied by microevolution resulting in genomic diversity between
strains of the same clonal lineage . -
pubmed
CONCLUSIONS : The higher geographical and temporal distance of the clone CHA isolates was associated with an increased intraclonal genome diversity compared to the more closely related clone
TB isolates derived from a common source demonstrating the impact of habitat adaptation on the microevolution of
P. - pubmed
We describe an expansile necrotising
pneumonia caused by
Norcardia in a
HIV - infected 3 - week - old baby . -
pubmed
SHU atypical (
aHUS ) , that is , not associated with
Escherichia coli Shiga toxinproducing , is seen in 5 to 10 % of cases of
Hemolytic Uremic Syndrome (
HUS ) , and can occur at any age and may be sporadic or familial . -
pubmed
Dysregulated
phosphatidylinositol signaling promotes endoplasmic - reticulum - stress - mediated
intestinal mucosal injury and
inflammation in
zebrafish . -
pubmed
INTRODUCTION :
Postoperative sore throat is a common complaint in
patients with endotracheal intubation and has potentially dangerous complications . -
pubmed
We determined whether use of a mandatory checklist of perioperative practices believed to reduce the risk of
prosthesis infection would impact
patient safety . -
pubmed
Although the specific factors that led to the
infection outbreak and subsequent cessation of
infections are unknown , we have shown that use of a checklist was associated with a dramatic impact on
patient safety . -
pubmed
This is determined by the exposure of
patients in
shock with acutely damaged end - organs and high
catecholamine support to a significant surgical
trauma . -
pubmed
OBJECTIVE : To evaluate the efficacy and tolerability of a multimodal skin - brightening regimen in
subjects with
facial hyperpigmentation . -
pubmed
RESULTS : At baseline and Weeks 4 , 8 , and 12 ,
subjects were assessed for overall
hyperpigmentation and global improvement . -
pubmed
Vaccination against
oncogenic human papillomavirus infection in
HIV - infected populations : review of current status and future perspectives . -
pubmed
UNLABELLED : Background Men and women with
HIV infection are at increased risk of developing
cancers associated with
human papillomavirus (
HPV ) . -
pubmed
The two licensed prophylactic
HPV vaccines protect against de novo infection with
HPV-16 and
HPV-18 , which cause the majority of
HPV - associated cancers . -
pubmed
To specifically recommend prophylactic
HPV vaccination in people with
HIV , the vaccines must be safe and immunogenic in immunosuppressed people at a high risk of
HPV infection . -
pubmed
This review aims to summarise the current knowledge from published
HPV vaccine trials in
HIV - infected populations , to compile scheduled and ongoing
HPV vaccine trials with
HIV - positive study populations and to extrapolate the relevant knowledge about
HPV vaccine efficacy in HIV - negative populations to an HIV context . -
pubmed
CONCLUSION : Prophylactic
HPV vaccination appears safe , immunogenic and , by extrapolation , likely to reduce
HPV - associated cancer development among persons with
HIV infection . -
pubmed
The combined chemoimmunotherapy was applied in the treatment of
mice with subcutaneously ( SC ) growing , advanced
MC38 colon carcinoma . -
pubmed
CONCLUSION :
Iron - based
phosphate binders are as effective as sevelamer and well tolerated for
hyperphosphatemia in dialysis
patients . -
pubmed
Iron - based
phosphate binders appear to have a beneficial effect on
renal anemia in
patients receiving dialysis . -
pubmed
Information was obtained for each
patient treated , including pulp and peri - radicular diagnosis for the tooth , presence of pre - operatory
pain , type of medication being used , type of instrumentation technique used and number of appointments needed to complete the root canal treatment . -
pubmed
CONCLUSIONS : Flare - ups were found to be affected significantly by gender of patient , presence of
radiolucent lesions ,
patients taking pre - operative analgesic or anti - inflammatory drugs and on type of instrumentation technique . -
pubmed
METHODS : We measured EIM in 8 arm and leg muscles in 61
boys with
Duchenne muscular dystrophy (
DMD ) and 31 healthy
boys , ages 3 - 12 years , at 5 centers . -
pubmed
DESIGN :
Body mass index , triceps skinfolds , and waist , arm , and leg circumferences were collected on 29
adolescents aged 14 - 17 yrs with
spinal cord injury ,
cerebral palsy , or
spina bifida . -
pubmed
Non - stenotic intracranial arteries have atherosclerotic changes in
acute ischemic stroke patients : a 3 T MRI study . -
pubmed
METHODS : Thirty - three
patients with
acute ischemic stroke and 36 control
patients were analyzed . -
pubmed
Acute
ischemic stroke patients were divided according to TOAST classification . -
pubmed
AreaInner did not significantly differ between
stroke patients and controls ( P = 0.619 ) . -
pubmed
However , AreaOuter , AreaVW , and RI were significantly larger in
stroke patients ( P & lt ; 0.001 ) . -
pubmed
CONCLUSION : In
patients with acute
ischemic stroke , wall thickening and positive remodeling are evident in non - stenotic intracranial arteries . -
pubmed
CASE : A 30 - year - old
patient with a previous cesarean delivery was undergoing surgical termination of pregnancy at 13 weeks ' gestation for a lethal
fetal malformation . -
pubmed
Acute oral complications in a pediatric
patient with
acute lymphoid leukemia . -
pubmed
Pseudomonas aeruginosa is a low - virulence pathogen that can cause
infection in immunocompromised patients . -
pubmed
aeruginosa as the bacteria responsible for
intraoral inflammation , and antibiotic therapy targeting
P. - pubmed
Here , we report a case involving a 10 - year - old
patient with
acute lymphoid leukemia (
ALL ) , in which
P. - pubmed
Comparison of the
Hyaluronic Acid Vaginal Cream and Conjugated
Estrogen Used in Treatment of
Vaginal Atrophy of Menopause
Women : A Randomized Controlled Clinical Trial . -
pubmed
BACKGROUND :
Vaginal atrophy is a common complication in menopause which does not improve with time and , if untreated , can affect the quality of life for
women . -
pubmed
METHODS : This study was a randomized controlled clinical trial on 56 menopausal
women with symptoms of
vaginal atrophy ; they were randomly allocated to two groups ( recipient conjugated
estrogen and
hyaluronic acid ) . -
pubmed
METHODS : A retrospective review of all surgical
patients with
non - small cell lung cancer at a single institution imaged between 2000 and 2006 with
( 18 ) F - fluorodeoxyglucose positron emission tomography before or after induction therapy was performed . -
pubmed
[ Ecological executive function characteristics and effects of executive function on social adaptive function in school - aged
children with
epilepsy ] . -
pubmed
OBJECTIVE : To explore the characteristics of ecological executive function in school - aged
children with idiopathic or probably
symptomatic epilepsy and examine the effects of executive function on social adaptive function . -
pubmed
METHODS : A total of 51 school - aged
children with idiopathic or probably symptomatic
epilepsy aged 5 - 12 years at our hospital and 37 normal ones of the same gender , age and educational level were included . -
pubmed
RESULTS : The scores of school - aged
children with idiopathic or probably symptomatic
epilepsy in global executive composite ( GEC ) , behavioral regulation index ( BRI ) and metacognition index ( MI ) of BRIEF ( ( 62 + -12 ) , ( 58 + -13 ) and ( 63 + -12 ) , respectively ) were significantly higher than those of the control group ( ( 47 + -7 ) , ( 44 + -6 ) and ( 48 + -8 ) , respectively))(P<0.01 ) . -
pubmed
The scores of school - aged
children with idiopathic or probably symptomatic
epilepsy in adaptive behavior quotient ( ADQ ) , independence , cognition , self - control ( ( 86 + -22 ) , ( 32 + -17 ) , ( 49 + -14 ) , ( 41 + -16 ) , respectively ) were significantly lower than those of the control group ( ( 120 + -12 ) , ( 59 + -14 ) , ( 59 + -7 ) and ( 68 + -10 ) , respectively))(P<0.01 ) . -
pubmed
CONCLUSIONS : School - aged
children with idiopathic or probably symptomatic
epilepsy may have significantly ecological executive function impairment and social adaptive function reduction . -
pubmed
RESULTS : A total of nine studies were included in the analysis , including 384
patients with 390
aneurysms . -
pubmed
Moreover , the search for competitive alternatives to using
colistin with
swine is of paramount importance to preserve the effectiveness of this antibiotic for the treatment of
MDR - GNB infections in
human medicine . -
pubmed
For this purpose we exposed male
zebrafish to two types of social interactions : ( 1 ) real opponent interactions , from which a Winner and a Loser emerged ; and ( 2 ) mirror - elicited interactions , that produced individuals that did not experience a change in social status despite expressing similar levels of
aggressive behavior to those of participants in real - opponent fights . -
pubmed
OBJECTIVE : This study aimed to assess the presence of
pancreatic hyperenzymemia in
patients with
pancreatic cystic lesions as compared to other
chronic diseases of the pancreas . -
pubmed
METHODS : Ninety - one
patients were studied : 32 had
mucinous cystic lesions , 35 had
chronic pancreatitis (
CP ) , and 24 had
pancreatic ductal adenocarcinoma (
PDAC ) . -
pubmed
Surgery was carried out in 10 of the 32
patients with
mucinous cystic lesion ( 7 of them had severe
dysplasia ) , in 5
patients with
CP , and in 9
patients with
PDAC . -
pubmed
BACKGROUND AND OBJECTIVE :
Patients with small ( & lt;5 mm ) unruptured
intracranial aneurysms (
UIAs ) are at risk of
subarachnoid hemorrhage , but risk assessment of these patients remains controversial in daily clinical practice . -
pubmed
We aimed to identify the risk factors of
aneurysmal rupture in these
patients . -
pubmed
METHODS : We retrospectively analyzed consecutive
patients with small
UIAs who were admitted to our center between February 2009 and December 2014 . -
pubmed
RESULTS : A total of 548
patients with 618 small
intracranial aneurysms ( 267 ruptured and 351 unruptured ) were included . -
pubmed
Factors associated with acute - phase response of
bisphosphonate - naive or pretreated
women with
osteoporosis receiving an intravenous first dose of
zoledronate or
ibandronate . -
pubmed
Univariate and multivariate analyses suggested that miR-103 overexpression was a poor independent prognostic factor for triple - negative
breast cancer patients . -
pubmed
Comparative analysis of
HPV16 gene expression profiles in
cervical and in oropharyngeal squamous cell carcinoma . -
pubmed
Human papillomavirus type 16 (
HPV16 ) is the major cause of
cervical cancer and of a fraction of
oropharyngeal carcinoma . -
pubmed
Bioinformatics Analysis on Molecular Mechanism of
Green Tea Compound
Epigallocatechin-3 - Gallate Against
Ovarian Cancer . -
pubmed
Intensive preoperative rehabilitation improves functional capacity and postoperative hospital length of stay in elderly
patients with
lung cancer [ synopsis ] . -
pubmed
Giant
RPLS commonly occurs in
adults aged 40 - 60 y and presents atypical clinical manifestations . -
pubmed
A Case of
Ophitoxaemia - Snake
Poisoning : Snake Identified ,
Echis Carinata , by the Natural History Society , Bombay . -
pubmed
INTRODUCTION : Treatment for
anal fistulas in
patients with
Crohn ' s disease is still challenging , even for the expert surgeon . -
pubmed
METHODS : A systematic review of the literature , selecting series of
patients affected by
Crohn ' s disease and
anal fistulas and treated using advancement flap technique was performed . -
pubmed
CONCLUSION : The review concludes that the advancement flap technique to treat
anal fistulas in
patients with
Crohn ' s disease is an adequate alternative . -
pubmed
Notably , 3 - S - fire - exposed
mice were the only group to develop
acute lung injury , possibly because they inhaled the highest concentrations of hazardous air toxicants ( e.g. -
pubmed
Hepatoprotective effects of
garlic against
ethanol - induced
liver injury : A mini - review . -
pubmed
Along with the prosperity in the use of herbal medicines for the treatment of
human diseases in recent decades , a series of studies have focused on the beneficial effects of
garlic against
ALD . -
pubmed
This mini - review highlighted the protective roles of
garlic against
ALD and the potential mechanisms . -
pubmed
Results : The most potent
antitussive effect was observed for
Nigella sativa and
Linum usitatissimum on
coughs induced by
sulfur dioxide . -
pubmed
Artemisia absinthium showed a higher
antitussive effect on
cough induced by
ammonia compared with the other studied medicinal plants . -
pubmed
The
antitussive effects of
Cuminum cyminum and
Glycyrrhiza glabra were more potent on
cough induced by
citric acid than other medicinal plants . -
pubmed
Spotlight on
eltrombopag in the treatment of
children with
chronic immune thrombocytopenia . -
pubmed
The intensive care service ( ICS ) saves lives and rescues the neurological function of
stroke patients . -
pubmed
We wondered the different utilization of ICS for
patients with
ischemic and
hemorrhagic stroke , especially those who died within 30 days after
stroke . -
pubmed
Sixty - seven
patients died during 2011 to 2015 due to acute
stroke ( 42 due to
intracranial hemorrhage [
ICH ] ; 25 due to
cerebral infarct [ CI ] ) . -
pubmed
Diverse
human tumors obtained directly from surgery or biopsy can grow at high frequency in 3 - dimensional Gelfoam histoculture for long periods of time and still maintain many of their in vivo properties . -
pubmed
This is the first report on the efficacy of
colchicine in a
patient with
AOSD which was refractory to immunosuppressive treatments including biologics . -
pubmed
CASE PRESENTATION : A 24 - years Japanese female
patient was referred to our hospital for the flare - up of
AOSD under the combined treatments with
steroid , immunosuppressants , and biologics . -
pubmed
Glioblastoma multiforme (
GBM ) is the most lethal
glioma variant in the adult brain and among the deadliest of
human cancers . -
pubmed
The nucleotide sequences of 24
BQCV isolates showed the highest identity ( 86.4 % ) with
strains from Europe at the polyprotein gene , whilst the Serbian isolates between each other showed 98.5 % similarity . -
pubmed
Evaluating the suitability of honey for the detection of the
viral disease by simultaneous testing of live ,
dead bees , and honey from the same
hive , it was shown that the honey can be successfully used for the detection of
BQCV . -
pubmed
OBJECTIVES : The primary objective of this observational study was to determine whether
caffeine consumed habitually as part of a daily diet was associated with experimental
pain sensitivity using noxious stimuli in a non - clinical sample of 62 community - dwelling
adults between 19 and 77 years old . -
pubmed
At the end of treatment , arterial BP was measured , and hyperinsulinemic - euglycemic clamps were performed in conscious
obese mice receiving vehicle ,
captopril ,
captopril plus
A779 , or
A779 ( n = 6 - 13 / group ) . -
pubmed
Safety and efficacy of mechanical thrombectomy with stent - retrievers in anticoagulated
patients with
anterior circulation stroke . -
pubmed
RESULTS : The following statistically insignificant differences were found in 26
patients on OAC versus 259
patients without OAC : occurrence of symptomatic
intracerebral haemorrhage 7.7 % versus 8.1 % , achievement of successful recanalisation 69.2 % versus 82.6 % , good 90 - day clinical outcome 34.6 % versus 56.8 % , 90 - day mortality 26.9 % versus 20.8 % ( p>0.05 in all cases ) . -
pubmed
CONCLUSIONS : MT with stent - retrievers is safe and effective in
ACS patients on OAC . -
pubmed
[ Short - term Outcome of Uniportal and Three Portal Video - assisted Thoracic Surgery for
Patients with
Non - small Cell Lung Cancer ] . -
pubmed
METHODS : We retrospectively evaluated 266
patients with
NSCLC who underwent intended VATS lobectomy by a single surgical team in our ward between January 2016 and August 2017 . -
pubmed
Human lens epithelial cell line
SRA01 / 04 was subjected to
H 2 O 2 to mimic a cell model of
cataract . -
pubmed
METHODS : Epithelial and stromal tissues from
malignant and
normal human prostate were obtained by laser capture microdissection . -
pubmed
The
PTXL could be effectively uptaken into
human keloids fibroblast ( HKFs ) in a time - dependent manner . -
pubmed
Meanwhile , in vivo studies indicated that the
PTXL had better performance on inhibiting the
keloids growth compared to the
PTX in
keloid - bearing
BALB / c nude mice model . -
pubmed
Prevalence of
cognitive impairment in
patients with
substance use disorder . -
pubmed
DESIGN AND METHODS : The Montreal Cognitive Assessment was administered to
outpatients seeking treatment for
substance use disorder . -
pubmed
Patient characteristics ( age , years of regular use , polysubstance use , severity of dependence / abuse ,
depression ,
anxiety and stress ) were also taken into account . -
pubmed
Aqueous leaf extract of
Clinacanthus nutans improved metabolic indices and
sorbitol - related complications in
type II diabetic rats (
T2D ) . -
pubmed
All
rats except normal control
rats were fed with a high - fat diet for 8 weeks to induce
obesity and subsequently injected with 35 mg / kg
streptozotocin to induce
type II diabetes . -
pubmed
Diabetic rats administered with
C. - pubmed
Sorbitol levels in the kidney , lens , and nerve were reduced in
diabetic rats administered with
C. - pubmed
Although
MALDI - TOF mass spectrometry recognized all
Cronobacter sakazakii and
Cronobacter malonaticus strains , it could not identify
Cronobacter muytjensii strain . -
pubmed
Although
MALDI - TOF mass spectrometry recognized all
Cronobacter sakazakii and
Cronobacter malonaticus strains , it could not identify
Cronobacter muytjensii strain . -
pubmed
CASE REPORT : A 64 - year - old
woman presented with a 2 - year history of repeated right
waist pain and a 1 - month history of
nausea ,
vomiting , and frequent and urgent urination . -
pubmed
A CASE REPORT : The authors describe a case of a 72 - year - old
female with
primary AI (
Addison ' s disease ) after adrenalectomy due to
adrenal hypertrophy she underwent in childhood . -
pubmed
The authors suggest that each
patient with
adrenal crisis as well as with severe
hyponatremia should be evaluated by echocardiography . -
pubmed
Three
patients suffered perioperative complications ( including
colonic ischaemia , rectal
perforation and
arterial bleeding ) . -
pubmed
Five
patients ( 21.7 % ( 5/23 ) ) had an
anastomotic leak treated with Ta drainage in two
patients . -
pubmed
The aim of this study was to compare the treatment outcomes of chemotherapy , surgery , and combination therapy in
patients with lymph node - positive
bladder cancer . -
pubmed
From 1 January 2010 to 31 December 2015 ,
patients with
bladder cancer presenting local lymph node
metastasis at the time of diagnosis were treated with a single treatment strategy , with either radical cystectomy or chemotherapy or with a combined strategy using both . -
pubmed
Out of 230
patients with
bladder cancer , 44 ( 19.1 % ) were treated with palliative chemotherapy , 30 ( 13.0 % ) with neoadjuvant chemotherapy followed by cystectomy , 129 ( 56.1 % ) with cystectomy followed by adjuvant chemotherapy , and 27 ( 11.7 % ) with cystectomy alone . -
pubmed
This study represents an advancement in understanding the impact of clinical treatment patterns of lymph node - positive
bladder cancer through comparison of survival data of
patients treated with different therapeutic strategies . -
pubmed
Our findings support a favourable priming - induced acceleration of the VO2 kinetics response in middle - aged
individuals with uncomplicated
T2D attributed to an enhanced matching of microvascular
O2 delivery to utilisation . -
pubmed
It is worthy to note that only one
patient presented preoperatively with
bladder incontinence , urgency , and frequency . -
pubmed
Almost immediately in the postoperative phase , the
patient 's frequency and urgency improved , and the bladder function normalized within two weeks of having the
tumor removed . -
pubmed
Splenic ischemic preconditioning attenuates oxidative stress induced by
hepatic ischemia - reperfusion in
rats . -
pubmed
PURPOSE : To evaluate the effects of splenic ischemic preconditioning ( sIPC ) on oxidative stress induced by
hepatic ischemia - reperfusion in
rats . -
pubmed
Animals from IRI group were subjected to 45 minutes of partial
liver ischemia ( 70 % ) . -
pubmed
Eryngium carlinae Ethanol Extract Corrects Lipid Abnormalities in
Wistar Rats with Experimental
Diabetes . -
pubmed
Eryngium carlinae is a
plant used in traditional medicine to treat
lipid abnormalities . -
pubmed
Transcatheter Treatment of a Symptomatic
Giant Iliac Artery Aneurysm with a BeGraft Peripheral Stent in a 2 - Year - Old
Child . -
pubmed
A 2 - year - old
girl presented with severe
abdominal pain due to a giant iliac artery
aneurysm . -
pubmed
This case involves a 5 year old
boy with gross
hematuria who was found to have an 8 cm
pelvic mass , likely arising from the prostate and extending along the bladder wall . -
pubmed
Aim : The aim of this study was to assess treatment modalities , treatment response , toxicity profile ,
disease progression and outcomes in 14
patients with a confirmed diagnosis of primary
cutaneous T - cell lymphoma (
PCTCL ) treated with total skin electron beam therapy ( TSEBT ) . -
pubmed
Materials and Methods : This is a retrospective study of
patients with
PCTCL , diagnosed and treated in a reference center in Mexico City , analyzing treatment modalities , response to treatment , long - term outcome , and mortality . -
pubmed
Newcastle disease virus induces
testicular damage and disrupts steroidogenesis in specific pathogen free roosters . -
pubmed
Newcastle disease (
ND ) , which is caused by
Newcastle disease virus (
NDV ) , can cause heavy economic losses to the poultry industry worldwide . -
pubmed
If symptoms suggestive for
COVID-19 are reported , family members , including children < 14 years , are offered a pharyngeal swab taken at the Division of
Infectious Diseases and Tropical Medicine , LMU University Hospital Munich , for molecular testing for
SARS - CoV-2 . -
pubmed
The potential impact of
human visceral leishmaniasis vaccines on population incidence . -
pubmed
We implement four characteristics from different
human VL vaccine candidates into two published
VL transmission model variants to estimate the potential impact of these vaccine characteristics on population - wide anthroponotic
VL incidence on the Indian subcontinent ( ISC ) . -
pubmed
Defocus Curve and
Patient Satisfaction with a New Extended Depth of Focus Toric Intraocular Lens Targeted for Binocular
Emmetropia or Slight
Myopia in the Non - Dominant Eye . -
pubmed
Purpose : To evaluate the defocus curve and
patient satisfaction after implantation of an extended depth of focus ( EDOF ) toric IOL when both eyes were targeted for
emmetropia and when the non - dominant eye was targeted for mini monovision ( -0.50D ) . -
pubmed
Subjects presenting for routine
cataract surgery were assigned to one of two groups , both receiving bilateral toric EDOF lenses . -
pubmed
Measures of interest were the postoperative defocus curve and reported
patient satisfaction and
visual disturbances . -
pubmed
Here , we investigated variations in morphology , including body shape and skeletal
deformities , and genetic features among hatchery - born and recaptured
A. - pubmed
The diagnosis of
pulmonary hypertension before lung resection makes the perioperative management of these
patients more difficult and sometimes leads to rejecting
patients for surgery . -
pubmed
AREAS COVERED : We performed a review of literature on PubMed on
Pulmonary hypertension associated lung resection , preoperative assessment of lung resection and perioperative management of
PH patients , including guidelines and clinical trials . -
pubmed
In this review , we summarize the current state of knowledge regarding the pre and perioperative management of
patients with suspected or confirmed
PH who can benefit from surgical treatment of
lung cancer . -
pubmed
EXPERT OPINION : Management of
PH patients before lung resection should include a very careful workup including at least right heart catheterization with evaluation of the targeted PH treatment in an expert center and evaluation of other comorbidities . -
pubmed
We report a rare case of
renal immature teratoma diagnosed in a 6 months old female
patient , discuss its pathology and review relevant literature . -
pubmed
The present study aimed at selecting non - starter
lactic acid bacteria
strains , with desirable technological and enzymatic activities , suitable as adjunct culture for the
Provola dei Nebrodi cheese production . -
pubmed
Among the selected
strains ,
Lacticaseibacillus paracasei PN 76 and
Limosilactobacillus fermentum PN 101 were used as adjunct culture in pilot - scale cheese - making trials . -
pubmed
The volatile organic compound profiles of experimental cheeses was significantly different from those generated in the controls , suggesting that the selected adjunct
strains were able to accelerate the flavour development , contributing to a unique profile of
Provola dei Nebrodi cheese . -
pubmed
METHODS :
AP was induced in wild - type and C3 - deficient
mice by retrograde infusion of
taurocholate into the pancreatic duct . -
pubmed
Identification of
patients at risk of
IPS decline is of importance as follow - up , treatment and rehabilitation can be optimized . -
pubmed
These studies demonstrate that resistance to
amikacin in a laboratory
strain of
E. - pubmed
The relevance of the cholinergic system in mediating
hyperactive behaviour in
children is discussed . -
pubmed
[ Diagnostic characteristics of
anthrax in
swine ] . -
pubmed
Using food - deprived
rabbits we investigated the effects of
nutritional deficiency on the development of
pressure sores . -
pubmed
The
body weight of these
animals was decreased significantly from normal . -
pubmed
Protein deficiency in these
animals was indicated by serum tests , as well as by histologic features of liver and testis and ultrastructural findings on fibroblasts . -
pubmed
Histologic findings at each time were as follows : At day one , the degree of
ischemic skin destruction in the malnourished
animals was more severe than that in the normal ones , and
thrombi were occasionally seen in the malnourished cases . -
pubmed
At three days , epidermal cells covered the lesions in the case of normal
animals ; however , massive
necrosis of the epidermis was still recognized in the malnourished
rabbits . -
pubmed
Thus , the healing process of
pressure sores was strongly suppressed in the malnourished
animals . -
pubmed
[ Changes in
oxygen metabolism during active avoidance learning in spontaneously
hypertensive and normotensive
rats ] . -
pubmed
These changes are enhanced in ageing and most obvious under emotional - motor loads in
hypertensive animals . -
pubmed
Aortic onchocercosis due to
O. - pubmed
Comparative double - blind study of two dosage regimens of low - molecular weight
heparin in elderly
patients with a
fracture of the neck of the femur . -
pubmed
A randomized double - blind study comparing the efficacy and safety of two different dosage regimens of a low - MW
heparin ,
Enoxaparin (
Lovenox ) 20 mg twice ( group A ) or 40 mg once ( group B ) , was carried out in 103 elderly
patients with a
fracture of the neck of the femur . -
pubmed
Distal and proximal
thrombosis occurred in 18.3 % of
patients in group A and in 10.4 % in group B. -
pubmed
This trial suggests that a total daily dose of 40 mg of
Enoxaparin can be effective in the prevention of
deep vein thrombosis in elderly surgically treated
patients and does not involve a major risk of
bleeding . -
pubmed
To determine whether circulating platelets alter during asthmatic reactions induced by allergens , we studied nine subjects previously shown to develop an early or dual
asthmatic reaction after inhalation challenge with extracts of
house dust mite or
grass pollen . -
pubmed
Each subject developed an early
asthmatic reaction after allergen inhalation challenge , which was followed by a late
asthmatic reaction in six
subjects and by an equivocal late
asthmatic reaction in two of them ( fall in FEV1 of 15 and 17 % respectively ) . -
pubmed
Lipolysis in isolated myocardial cells from
diabetic rat hearts . -
pubmed
Diabetes in
rats was induced with
streptozotocin ( 100 mg / kg ) ; myocardial cells ( myocytes ) were isolated from the hearts 3 - 4 days later . -
pubmed
[ Serotoninergic and catecholaminergic indices in
patients with neurotic and
depressive disorders and changes in them as a result of reflexotherapy ] . -
pubmed
The status of the serotoninergic and catecholaminergic systems was studied in
patients with neurotic
depressive disorders before and after acupuncture ( AP ) . -
pubmed
Prior to
AP patients with
anxiety -
depressive ,
depressive - hypochondriac or asthenodepressive manifestations showed different changes in the parameters studied . -
pubmed
Improvement in biochemical parameters indicates that this type of therapy is an effective means of the treatment of
patients with
neuroses with the predominance of
depressive disorders . -
pubmed
Mouse skin photosensitivity with
dihaematoporphyrin ether (
DHE ) and
aluminium sulphonated phthalocyanine (
AlSPc ): a comparative study . -
pubmed
Relationship between serum free thyroid hormone concentrations and target organ responsiveness in
thyroid disease patients before and after treatment . -
pubmed
Relationship between serum free thyroid hormone concentrations and several markers of peripheral tissue response to thyroid status was studied in 24
patients with
hyperthyroidism , 17 with
euthyroidism with
goiter and 10 with
primary hypothyroidism before and after the initiation of standard forms of treatment . -
pubmed
These results indicate that these peripheral parameters correlated well with serum free
thyroid hormone concentrations in
thyroid disease patients . -
pubmed
Therefore , these parameters can be used to assess thyroid functions in
patients with
thyroid hormone resistance . -
pubmed
Domestic animals such as
dogs can be used as sentinels to provide information on the effects of contaminants in the environment and have been used to a limited extent to evaluate the environmental influences on the occurrence of
breast cancer and
osteosarcoma . -
pubmed
Eight atopic
individuals , 3 of whom having mild symptoms , with known
birch allergies were selected together with 3 control individuals . -
pubmed
volvulus was susceptible to
paralysis by
CGP 6140 ,
levamisole ,
pyrantel and
carbachol at concentrations of ten to a thousand times lower than those required to produce any influence on
B. - pubmed
The enzyme activity in
rat liver increased significantly in the early
diabetic ,
cholesterol - fed ,
CS 514- , and
CPIB - treated groups , but no change in its activity was observed in chronic
diabetic groups . -
pubmed
When chronic
diabetic rats were given a
cholesterol diet or treated with
CS 514 or
CPIB , the activity increased significantly . -
pubmed
Lymph node cells from sensitized
granuloma - bearing
mice with cutaneous anergy showed suppressed specific and nonspecific antigen - induced proliferative responses in vitro . -
pubmed
In a series of five experiments , the modulating role of
naloxone on a
scopolamine - induced
retention deficit in a passive avoidance paradigm was investigated in
mice . -
pubmed
It is postulated that complement activation and
glomerulonephritis in
staphylococcal endocarditis may be the direct result of a
bacterial product . -
pubmed
We studied serial brainstem auditory evoked potentials ( BAEPs ) in a
patient who had episodic
basilar migraine . -
pubmed
Seventy eight
patients with
chronic lung diseases were once or repeatedly vaccinated against
influenza with a bivalent inactivated vaccine . -
pubmed
Rhizobium meliloti 300hl3 reached the stationary phase of growth very quickly and had an early
death when 8.6 muM
parathion was added to the growth medium at the start of the culture . -
pubmed
Ascending
pyelonephritis in
dogs induced by
ureteral dysfunction . -
pubmed
Modified proton relaxation behaviour in erythrocytes from spontaneously
hypertensive rats . -
pubmed
Diethanolamine salts of the catalytically sulphurated
oleic acid ( X-303/1 ) and of the catalytically sulphurated
fatty acids isolated from
linseed oil ( X-303/2 ) were found to exhibit a strong cytotoxic in vitro activity against Ehrlich ascites
cancer cells with minimal cytotoxic effect on normal cells ( leukocytes ) of the peritoneal exudate in
rabbits . -
pubmed
The
Legionnaires ' disease bacterium (
Legionella pneumophila ) inhibits phagosome - lysosome fusion in
human monocytes . -
pubmed
[ Distant
metastases of
cervical cancer in
patients treated by radiotherapy ] . -
pubmed
Defective repair of
mitomycin C crosslinks in
Fanconi ' s anemia and loss in confluent normal
human and
xeroderma pigmentosum cells . -
pubmed
The immunofluorescence test on paraformaldehyde - fixed cells was used for the detection of antibodies bound to the platelets and granulocytes and present in the sera of 24
patients with
Evans syndrome and a further 29
patients with both
idiopathic thrombocytopenia (
ITP ) and
idiopathic neutropenia (
INP ) , but without
autoimmune haemolytic anaemia (
AIHA ) . -
pubmed
There is limited experience world wide in the management of
patients with
cystic fibrosis who undergo thoracotomy . -
pubmed
An 8 - year - old
boy with
cystic fibrosis and a chronic
infection of the right lung with
abscess formation underwent pulmonary resection after 1 week of antibiotic therapy with
tobramycin ,
ticarcillin and
cloxacillin , and physiotherapy . -
pubmed
Reduction of
reperfusion injury of
human myocardium by
allopurinol : a clinical study . -
pubmed
To determine the possibility of myocardial protection against
reperfusion injury by
allopurinol , 22 aortocoronary bypass
patients were studied . -
pubmed
The comparative efficacy of transcatheter arterial chemoembolization and percutaneous
ethanol injection ( PEI ) in the treatment of
hepatocellular carcinoma (
HCC ) was investigated in a series of 243 consecutive
patients : 146 of them were submitted to 1 - 6 chemoembolization sessions at 1 and 3 months ' intervals and 30 to
PEI ; the remaining 67
patients refused any treatment . -
pubmed
Management and outcome of low - grade
astrocytomas of the midline in
children : A retrospective review . -
pubmed
In the National Toxicology Program 2 - year inhalation study of
dichloromethane (
DCM ) , there was a significant increase in
pulmonary neoplasms in female
B6C3F1 mice exposed to 2000 ppm ( overall rates of 30/48 versus 5/50 in control ) . -
pubmed
The
patient underwent pterional craniotomy with
aneurysm clipping and thrombectomy to relieve mass effect , and has made a good recovery . -
pubmed
The treatment of a young
man with
lumbar spinal tuberculosis and neurological involvement is described . -
pubmed
DESIGN AND
PATIENTS : This prospective cohort study consisted of 311 inpatients with end - stage
congestive heart failure ,
chronic obstructive pulmonary disease ,
cancer , and
cirrhosis . -
pubmed
Active vaccination of patients with
HIV infection ( vaccine therapy ) safely alters the immune repertoire against
HIV . -
pubmed
OBJECTIVE : We describe the unusual
syndrome of
cytomegalovirus ( CMV ) polyradiculomyelitis and its MR findings in two
patients with
AIDS . -
pubmed
MATERIALS AND METHODS : The clinical records and MRI studies of two
patients with
AIDS and
CMV polyradiculomyelitis were reviewed . -
pubmed
CONCLUSION : The clinical presentation of
urinary retention ,
flaccid paraparesis , back and/or leg
pain , and " saddle anesthesia " in a
patient with
AIDS should suggest the diagnosis of
CMV polyradiculomyelitis . -
pubmed
Although
Helicobacter pylori (
HP )
infection has been considered to have an etiologic role in the development of
antral gastritis and
recurrence of
duodenal ulcer , the source and normal route of transmission of
HP remains unknown . -
pubmed
Similarly
RU486 was ineffective in inhibiting
lordosis in ovariectomized
rats treated only with
estradiol ( 3 micrograms of EB / day for 7 days ) . -
pubmed
Effect of mild
hypothermia on cerebral energy metabolism during the evolution of
hypoxic - ischemic brain damage in the immature
rat . -
pubmed
BACKGROUND AND PURPOSE : Intraischemic
hypothermia ( 34 degrees C and 31 degrees C ) has a profound neuroprotective effect on the brain of the immature
rat . -
pubmed
To determine the mechanisms by which mild to moderate
hypothermia affects cerebral energy metabolism of the brain of the newborn
rat pup , we examined alterations in cerebral glycolytic intermediates and high - energy
phosphate compounds during intraischemic and postischemic
hypothermia and correlated these findings with known
neuropathologic injury . -
pubmed
METHODS : Seven - day - old
rat pups underwent unilateral common carotid artery ligation and exposure to
hypoxia in 8 %
oxygen at either 37 degrees C , 34 degrees C , or 31 degrees C for 3.0 hours . -
pubmed
Separate groups were exposed to
hypoxia -
ischemia at 37 degrees C for 3 hours but recovered at either 37 degrees C , 34 degrees C , or 31 degrees C. At 60 , 120 , and 180 minutes of intraischemic
hypothermia and at 10 , 30 , 60 , and 240 minutes of postischemic
hypothermia , individual
rat pups were quick - frozen in liquid
nitrogen for later determination of cerebral concentrations of
glucose ,
lactate ,
ATP , and
phosphocreatine . -
pubmed
RESULTS : Cerebral
glucose was significantly higher and
lactate significantly lower in the 31 degrees C
animals during
hypoxia -
ischemia than either the 34 degrees C or 37 degrees C groups . -
pubmed
Postischemic
hypothermia of either 34 degrees C or 31 degrees C had no effect on the rate or extent of recovery of glycolytic intermediates or high - energy
phosphate compounds compared with the normothermic 37 degrees C
rat pups . -
pubmed
Thus , the mechanisms by which mild
hypothermia is neuroprotective are temperature dependent and may act at more than one point along the cascade of events eventually leading to
hypoxic - ischemic brain damage in the immature
rat . -
pubmed
Continuing transmission of
sexually transmitted diseases among patients infected with
HIV . -
pubmed
Fatty acid ethyl ester (
FAEE ) , a myocardial metabolite of
ethanol , causes
mitochondrial dysfunction in vitro in
rabbits . -
pubmed
Small
hepatocellular carcinoma in
patients with
chronic liver damage : prospective comparison of detection with dynamic MR imaging and helical CT of the whole liver . -
pubmed
MATERIALS AND METHODS : Fifty
patients with
chronic hepatitis or
liver cirrhosis underwent dynamic contrast - enhanced fast low - angle shot MR imaging and multiple - phase helical CT . -
pubmed
Diagnostic ability with both techniques was evaluated by means of receiver operating characteristic ( ROC ) analysis ; images in
patients with ( n = 27 ) and those without ( n = 15 )
HCC in whom the same anatomic levels were available for both examinations were assessed . -
pubmed
CONCLUSION : Arterial - phase dynamic MR imaging is superior to helical CT for the detection of
HCC in
patients with
chronic liver damage . -
pubmed
Against the dogma of the irreversibility of malignant cells , although
genetical abnormalities ,
human leukemic cells have been differenciated . -
pubmed
Liver cirrhosis was induced in
rats by
CCl4 administration . -
pubmed
The
glomerular filtration rate was slightly decreased in
cirrhotic rats but not altered after
bosentan treatment in either cirrhotic or control
rats . -
pubmed
Bosentan decreased
sodium excretion to a similar extent in both cirrhotic and control
rats , whereas water excretion was significantly reduced by both dosages of
bosentan in
cirrhotic rats only (
Cir + vehicle : 12.5 + /- 0.62 m day-1 ,
Cir + 6 mg kg-1 day-1
bosentan : 8.6 + /- 1.0 ml day-1 ;
Cir + 100 mg kg-1 day-1
bosentan : 7.4 + /- 0.6 ml day-1 ; n = 10 ; means + /- s.e.mean ) . -
pubmed
[ Apoptosis and
human viral infections ] . -
pubmed
Arrhenius analysis of the thermal response of
human colonic
adenocarcinoma cells in vitro using the multi - target , single - hit and the linear - quadratic model . -
pubmed
In the present paper we demonstrate this discrepancy with the two
human colonic
adenocarcinoma cell lines
WiDr and
SW620 . -
pubmed
Umbilical cord blood stem cells : application for the treatment of
patients with
hemoglobinopathies . -
pubmed
The review contains a discussion of the potential uses of UCB for
patients with
hemoglobinopathies and the value of programs designed to collect UCB from newborn infants with
hemoglobinopathies , from siblings of patients with
hemoglobinopathies , and from groups of ethnic minorities similar to those in which
hemoglobinopathies are found . -
pubmed
In this paper the Authors present the preliminary results of an investigation of a series of a
patients with
BPH who have undergone TUIP by modified monolateral incision . -
pubmed
From June ' 94 to April ' 96 at the Department of Urology of the Hospital of Matera , 56
patients with BPH - induced
cervico - urethral obstruction undergone TUIP . -
pubmed
[ Secondary
osteoporosis in
patients with
steroid - dependent
asthma ] . -
pubmed
The aim of the trial was estimation of frequency and degree of
osteoporosis in
steroid - dependent
asthma patients ( 48 persons : 18
men and 30
women ) . -
pubmed
Quantitative computer tomography revealed secondary
osteoporosis in 40.5 %
asthma patients . -
pubmed
PATIENTS AND METHODS : Between 1993 and 1995 , we encountered 15
patients with suspected
obturator hernia based on the presence of
bowel obstruction of unknown cause and so - called predisposing factors . -
pubmed
RESULTS : The 4
patients with
bowel obstruction caused by strangulated obturator
hernia were all correctly diagnosed preoperatively by ultrasonography and were successfully cured by surgery . -
pubmed
Mesenchymal hamartoma in a 21 - year - old
man . -
pubmed
in conscious
dogs with chronic
atrioventricular block and ventricular pacing at 50 to 130 beats / min . -
pubmed
We have studied mucosal tolerance in
autoimmune diabetes using the non - obese
diabetic mouse model . -
pubmed
A similar outcome was obtained when
patients were stratified by cytogenetics into FIPC and
UC groups . -
pubmed
Patients with
FIPC and a lower ratio ( less than median ) of either B2 : BX or PK*B2 : BX had a significantly higher remission induction rate ( 88 versus 69 % , P = 0.04 ) and longer survival ( median : 141 versus 80.5 weeks , P = 0.007 ) compared with those with ratios more than median . -
pubmed
For
patients with
UC , values of either B2 : BX or PK*B2 : BX below the median had an inferior response rate to induction therapy ( 35 versus 78 % , P = 0.0006 ) and inferior survival outcomes ( median survival : 11 versus 53 weeks , P = 0.00002 ) . -
pubmed
Chronically cannulated conscious
rats were subjected to 40 ml / kg of
hemorrhage and resuscitated with the shed blood and twice the volume of saline either under room air ( room air group ) or under 100 %
oxygen at 3 atmospheres absolute ( hyperbaric group ) . -
pubmed
Rats exposed to
HBO with no
hemorrhage served as controls . -
pubmed
In the present study , we have examined neurochemical correlates that may be involved in the differential cardiovascular responses observed in normotensive and
hypertensive rats during stress . -
pubmed
Using a restraint stress paradigm , both normotensive Wistar Kyoto ( WKY ) and Spontaneously
Hypertensive rats ( SHR ) underwent acute ( 1 h restraint in a perspex tube ) , chronic ( 1 h restraint for ten consecutive days ) or no restraint ( control ) stress . -
pubmed
Male
Wistar rats ( n = 20 , 4 mo old ) and 20 male Bio Breeding Wistar ( BB / W )
rats of the same age were used ; the
Wistar rats represent the control non -
diabetic rats while the BB / W
rats represent the
diabetic group . -
pubmed
The most interesting aspects of
parathyroid disease are the increased incidence of
primary hyperparathyroidism , which nowadays is diagnosed more and more frequently through the casual discovery of
hypercalcaemia , the various diagnostic methodologies used , the ongoing debate as to the function of parathyroidectomy in asymptomatic
patients and the new video - assisted surgical techniques which have recently been developed . -
pubmed
There were no cases of mortality , and 9.6 % of
patients presented specific morbidity characterised by some degree of
paraesthesia . -
pubmed
OBJECTIVE : To report a case of successful treatment of refractory
hot flashes with
gabapentin in a
patient with
prostate cancer who was receiving combination antiandrogen and
gonadotropin hormone - releasing hormone (
GnRH ) analog therapy . -
pubmed
CASE SUMMARY : A 70 - year - old white
man with a history of advancing
prostate cancer experienced disabling
hot flashes from combination therapy with the antiandrogen
bicalutamide and the
GnRH analog
goserelin acetate . -
pubmed
CONCLUSIONS :
Hot flashes resulting from antiandrogen or
GnRH analog therapy are often difficult to treat and leave many
patients disabled . -
pubmed
[ Hematogenous ( suspected-)
septic inflammation of the synovial fossa in the adult
horse : rare but deceptive ( 3 case reports ) ] . -
pubmed
Septic inflammation of the synovial fossa in the
horse is a severe disorder that can lead to permanent invalidity . -
pubmed
Three cases of suspected haematogenous septic
synovitis are described in adult
horses ( older than 1 year ) . -
pubmed
In two
horses , timely and adequate treatment resulted in recovery , but this was followed by fatal
recurrence . -
pubmed
In one of these
horses a persistent primary
infection was found as cause ; the other
horse was not available for autopsy . -
pubmed
It can be concluded that , in
horses with suspected haematogenous
septic inflammation of the synovial fossa , attention should be paid to the primary process -- it is not enough to treat the
synovitis alone . -
pubmed
PURPOSE : To determine whether the patient - based assessment of difficulty in mobility , developed and validated in a group of patients with
retinitis pigmentosa (
RP ) , is valid for measuring perceived visual ability for independent mobility in
patients with
glaucoma . -
pubmed
METHODS : A mobility questionnaire that had previously been developed was administered to 83
patient - volunteers who had various amounts of
visual impairment caused by
glaucoma . -
pubmed
These studies characterize drug - specific T cells in
CBZ - hypersensitive
patients that are phenotypically different from T cells involved in other serious cutaneous
adverse drug reactions . -
pubmed
Over the last two decades , several studies have reported a high prevalence of
cardiovascular disease in
patients with
end - stage renal disease (
ESRD ) . -
pubmed
Until larger RCTs of longer duration , which correct the existing methodological flaws , are designed and carried out , it is best not to recommend
garlic be used to treat mild to moderate
hyperlipidemia . -
pubmed
[
MENINGOCOCCAL INFECTIONS ARE DISTRIBUTED OVER THE WHOLE YEAR ] . -
pubmed
BACKGROUND : Adverse reactions to nonsteroidal anti - inflammatory drugs ( NSAIDs ) are frequent , particularly among
patients with
chronic urticaria or
asthma . -
pubmed
METHODS : We studied 216
patients ( 164
females and 52
males ) who had suffered adverse reactions to one or more NSAIDs ; 98
subjects ( 45.4 % ) had experienced reactions to only one NSAID ( single
hypersensitivity ) and 118 subjects ( 54.6 % ) had reacted to multiple NSAIDs ( multiple
hypersensitivity ) . -
pubmed
Cutaneous reactions were reported by 79.6 % of the
subjects ,
respiratory symptoms by 10.7 % ,
cutaneous and respiratory symptoms by 8.3 % ,
anaphylaxis by 1.4 % . -
pubmed
CONCLUSIONS : Considering previous studies and our own data ,
rofecoxib was well tolerated by all of the 174
patients with exclusively NSAID - related
respiratory symptoms . -
pubmed
[ Serum
homocysteine ,
vitamin B12 and
folic acid concentrations in
patients with
alcoholic liver cirrhosis ] . -
pubmed
The aim of the work was to establish serum
homocysteine ,
vitamin B12 and
folic acid concentrations in
patients with
alcoholic liver disease . -
pubmed
Hyperhomocysteinemia ( concentration & gt ; 12 mmol//l ) was stated in 50 % of the
patients and mean
homocysteine concentration was statistically significantly higher if compared to the controls ( 13.29 + /- 8.16 vs 11.03 + /- 1.6 mmol / l p & lt ; 0.05 ) . -
pubmed
A negative correlation between
homocysteine concentration and
folic acid concentration in the group of the
patients with
hyperthomocysteinemia was observed ( r = -0.88 , p & lt ; 0.001 ) and among all the
patients ( r = -0.312 , n.s . ) -
pubmed
Correction of disturbed respiratory function and inhibition of progression of pulmonary inflammatory and obstructive processes is the aim of respiration rehabilitation in
patients with
chronic bronchitis (
CB ) . -
pubmed
It is known that rehabilitation in
CB patients with
spinal diseases meets with difficulties as
dystrophic lesions of the spine entail its functional - anatomic disorders at the corresponding level . -
pubmed
New approaches to rehabilitation of
CB patients with
spinal lesions lie in use of pharmacopuncture , acupuncture , deep reflex - muscular massage and therapeutic exercise in consensual sequence . -
pubmed
This agent appears to be particularly promising clinically in the treatment of
reperfusion injury , for example in combination with reperfusion strategies during the acute phase of
myocardial ischemia or
infarction , or in the reduction of the pro - remodeling effects of
ischemia in
patients with
chronic ischemic syndrome and
left ventricular dysfunction . -
pubmed
The induction of
acute ileitis by a single microbial antigen of
Toxoplasma gondii . -
pubmed
Oral
infection of susceptible C57BL/6
mice with
Toxoplasma gondii results in a lethal
ileitis within 7 - 9 days postinfection . -
pubmed
C57BL/6
mice orally infected with Deltasag1 parasites failed to develop
ileitis . -
pubmed
RAG - deficient ( RAG1 (-/- ) ) mice are resistant to the development of the
ileitis after
T. - pubmed
In addition , resistant
mice ( BALB / c ) that fail to develop
ileitis following oral
infection with
T. - pubmed
Impella Recover 100 : successful perioperative support for off pump coronary artery bypass grafting surgery in a
patient with end - stage
ischemic cardiomyopathy . -
pubmed
The authors present the successful use of the Impella recover 100 intracardiac left ventricular assist device in a 55 - year old
man suffering from end - stage
ischemic cardiomyopathy . -
pubmed
[ Botulinic toxin in
patients with
neurogenic dysfunction of the lower urinary tracts ] . -
pubmed
Botulinic toxin ( BT ) is a new method of lowering intraurethral pressure in symptoms of obstructive voiding in
patients with
neurogenic dysfunction of the lower urinary tracts ( LUT ) . -
pubmed
Transperineal introduction of 100 units of BT type A (
botox , Allergan ) was used under electromyographic control into the external urethral sphincter of 9
patients ( 6
males and 3
females ) with LUT
neurogenic dysfunction aged 17 to 68 years ( mean age 37.2 years ) . -
pubmed
Two
patients had subnormal detrusor contractility due to
myelodysplasia and
diabetic polyneuropathy , two other
patients -- non - incontinent striated urethral sphincter after
hemorrhagic stroke and
spinal contusion , five
patients suffered from
detrusor - sphincteral dyssynergia (
DSD ) resultant from
Schmorl ' s hernia ,
multiple sclerosis ,
Charcot - Marie disease and
ischemic stroke of the spinal cord . -
pubmed
In 10 days residual urine was not found in 2
patients with subnormal detrusor contractility and in 4
patients with
DSD . -
pubmed
Mean maximal urinary flow rate rose from 4.3 to 9.6 ml / s. In 20 days , on the average ,
suprapubic fistula healed in all the
patients . -
pubmed
Electroretinographic examinations were made in 191
patients with non - proliferative and pre - proliferative
diabetic retinopathy . -
pubmed
Several studies in a variety of breeds have reported at least two QTL for milk production traits , including milk fat synthesis on
bovine chromosome 6 ( BTA6 ) , comprising a region that comparatively has been mapped to equivalent syntenic chromosome intervals in
human ,
pig , and
mouse harboring loci associated with
type II diabetes and
obesity - related traits . -
pubmed
METHODS :
Colitis was induced by oral administration of dextran
sodium sulfate ( 5 % ) to
C57BL / 6 mice for 7 days . -
pubmed
Aspects of the phenomenon which are discussed include physiological changes and their anatomical location , the effects of total and selective
sleep deprivation in the
human and
animal , and
REM sleep behavior disorder , the latter with its clinical manifestations in the
human . -
pubmed
We report the case of a 65 - year - old
man WDK , who experienced selective loss of timbre perception for keyboard and percussion instruments following a right temporal
stroke comprising the anterior superior and medial gyrus and parts of the insular region . -
pubmed
To identify potential factors mediating drug resistance to
melanoma cells , the mRNA expression profiles of the parental drug - sensitive
human melanoma cell line
MeWo and four derived drug - resistant sublines with acquired resistance against four commonly used drugs for
melanoma treatment (
cisplatin ,
etoposide ,
fotemustine and
vindesine ) were analysed . -
pubmed
[ Combining high - risk
human papillomavirus DNA test and cytological test to detect early
cervical dysplasia ] . -
pubmed
OBJECTIVE : To assess the value of combining high - risk
human papillomavirus (
HPV ) DNA test and cytological test in detection of early
cervical dysplasia . -
pubmed
Based on the criteria of histology and pathology , the sensitivity , specificity , positive - predictive value and negative - predictive value of high - risk
HPV DNA test for detecting all cases of
CIN II , III were 92.22 % , 74.71 % , 5.19 % and 99.84 % respectively . -
pubmed
METHODS :
Epilepsy patients on
VPA - DR were offered the chance to convert to
VPA - ER . -
pubmed
Early paracentral
visual field loss in
patients taking
hydroxychloroquine . -
pubmed
Thirty - five
patients ( 13.4 % ) had
visual field abnormalities , which were attributed to
hydroxychloroquine treatment in 4
patients ( 1.5 % ) . -
pubmed
The effect of surgery on quality of life in
patients with
faecal incontinence of obstetric origin . -
pubmed
OBJECTIVE : To evaluate the results of surgery in the treatment of
faecal incontinence of obstetric origin and assess the effect of treatment on the quality of life of these
patients . -
pubmed
PATIENTS AND METHODS : A consecutive series of 43
patients , who had undergone surgery for severe
faecal incontinence of obstetric aetiology between March 1990 and March 2004 , was studied . -
pubmed
CONCLUSION : Surgical treatment of
faecal incontinence of obstetric origin achieves good results in a high percentage of
patients and has a positive effect on their quality of life . -
pubmed
BACKGROUND : There is a growing interest for the use of local ablative techniques in
patients with
non - resectable colorectal liver metastases . -
pubmed
METHODS : A consecutive series of 201
colorectal cancer patients , without
extrahepatic disease , that underwent laparotomy for surgical treatment of liver
metastases , were prospectively followed for survival and HRQoL. -
pubmed
At laparotomy three groups were identified :
patients in whom radical resection of
metastases proved feasible ,
patients in whom resection was not feasible and received local ablative therapy , and
patients in whom resection or local ablation was not feasible for technical reasons and who received systemic chemotherapy . -
pubmed
Oral
rabies vaccine ( ORV ) bait uptake by captive
striped skunks . -
pubmed
Aerial delivery of oral
rabies vaccine ( ORV ) baits has proven effective in large - scale efforts to immunize wildlife against
rabies , and in North America this strategy currently is being used to immunize foxes (
Urocyon cinereoargenteus and
Vulpes vulpes ) ,
raccoons (
Procyon lotor ) , and
coyotes (
Canis latrans ) . -
pubmed
Skunks are also a major reservoir and vector of
rabies , but at present oral vaccines for use in skunks are not licensed . -
pubmed
BACKGROUND :
Patients with unicompartmental
osteoarthritis of the knee can be treated with a correction osteotomy . -
pubmed
A successful outcome of the osteotomy relies on proper
patient selection , stage of
osteoarthritis , achievement and maintenance of adequate operative correction . -
pubmed
SELECTION CRITERIA : Randomised and controlled clinical trials comparing a high tibial osteotomy or a distal femoral osteotomy in
patients with unicompartmental
osteoarthritis of the medial or lateral compartment of the knee . -
pubmed
MAIN OUTCOME MEASURE : We observed the
patients for 5 months and compared the occurrence rate of
synechia formation between the 2 groups . -
pubmed
Pyruvate reduces in vitro the
embryotoxic effect of peritoneal fluid from infertile
women with
endometriosis . -
pubmed
OBJECTIVES : To ascertain the
embryotoxicity of peritoneal fluid from infertile
women with
endometriosis ( PF - E ) , on
mouse embryos in culture and to examine the effect of
pyruvate in the culture medium on PF - E induced
embryotoxicity . -
pubmed
STUDY DESIGN : Blood - free peritoneal fluid samples were obtained during laparoscopic investigation for
infertility from 21 infertile
women with
endometriosis . -
pubmed
They were then cultured in modified Whitten 's medium ( mWM ) with peritoneal fluid from
patients with
endometriosis , and either in the absence or presence of excess
pyruvate ( 0.062 mmol(-1 ) ) . -
pubmed
Urinary tract calculi in recumbent
patients . -
pubmed
In this article , we report an interesting case of a young
woman who presented with this rare type of reverse
apical ballooning syndrome occurring after
amphetamine use . -
pubmed
[ Cognitive performances in workers with
chronic virus hepatitis (
HBV -
HCV ) ] . -
pubmed
The sample of 21
workers suffering from chronic
viral hepatitis in drug treatment has been studied with a battery of standardized tests to assess the cognitive performance , the neurobehavioral effects and
psychological disorders that interfere with quality of life , comparing the results of subjects with
HBV with those of subjects suffering from
HCV . -
pubmed
The results showed that both subjects with chronic
HBV and
HCV have relational - work restrictions that determine long periods of absence from the workplace , with the
depression ,
anxiety ,
irritability and
dysphoria . -
pubmed
It is that in patients with chronic
HCV physical functioning is significantly impaired with clinical manifestations of the disease that lead to major
depression and
deficit cognitive function . -
pubmed
22
subjects diagnosed with
AD , mean Mini Mental State Exam ( MMSE ) score 22.2 , and 16 healthy elderly controls were imaged with a volumetric arterial spin labeling blood flow MRI technique and an anatomical imaging method using the identical spatial resolution , image orientation , and spatial encoding strategy . -
pubmed
CONCLUSION : In this article , we outline the technique of thoracoscopic resection of paraspinal
neurogenic tumors through an operative video and a review of the literature to summarize the surgical outcomes of
patients with these lesions . -
pubmed
We divided
individuals into three groups according to plasma
homocysteine levels and compared their risk for the development of new and progression of existing
OA . -
pubmed
Visual hallucinations in a
patient with adult onset
acid maltase deficiency disorder . -
pubmed
A 66 - year - old
male presented with
visual hallucinations . -
pubmed
METHODS : We studied 18 severely
obese but otherwise healthy
men . -
pubmed
Overall , the anatomic form - stable
silicone gel breast implants , when placed sub fascially , improve common complications such as
capsular contracture and
implant rupture with improved aesthetic outcomes and
patient satisfaction . -
pubmed
METHODS : One hundred
patients with histologically proven
adenocarcinoma of the lung were included in this retrospective analysis . -
pubmed
Our findings suggest that the percentage SUVmax change over time is a strong prognostic factor in
patients with
lung adenocarcinoma and can be complementary to the other well - known factors . -
pubmed
Prospective longitudinal studies of
head - injured individuals , with neuropathological verification , will not only improve understanding of
head trauma as a risk factor for
dementia but will also enhance treatment and prevention of a variety of
neurodegenerative diseases . -
pubmed
Various preparations of
estrogen and
progestogen are prescribed for young
women with
POF . -
pubmed
A matched prospective cohort study on
Staphylococcus aureus and
Escherichia coli bloodstream infections : extended perspectives beyond resistance . -
pubmed
BACKGROUND :
Bacteremias caused by
Staphylococcus aureus and
Escherichia coli are among the most common
bloodstream infections (
BSIs ) in adults . -
pubmed
The aim of the study was to investigate risk factors for
infection and clinical outcomes of
bacteremias caused by
S aureus or
E coli . -
pubmed
METHODS : We conducted a 1 - year matched prospective cohort study including 150
patients with
BSI caused by susceptible or resistant
S aureus or
E coli and 300 controls without
BSI caused by these organisms . -
pubmed
We identified 4 independent risk factors for acquisition of
S aureus bacteremia ( emergency , peripheral or central vascular catheter ,
renal disease ) and 6 risk factors for
E coli bacteremia ( emergency , peripheral or central vascular catheter ,
malignancy , cytoreductive or immunosuppressive therapy ) . -
pubmed
We observed a 5 - fold increase in the 30 - day mortality rate for
bacteremias due to
S aureus , and a 2 - fold increase in
BSI caused by
E coli . -
pubmed
CONCLUSION : Longer hospitalization periods and increased mortality of
bacteremias caused by
S aureus or
E coli , irrespective of susceptibility , implicate controlling for risk factors at an early stage . -
pubmed
However , few studies have examined gait in
PD patients who fall . -
pubmed
This study reports on the complexities of walking in
PD patients who reported falling during a 12 - month follow - up . -
pubmed
Forty - nine
patients clinically diagnosed with idiopathic
PD and 34 controls had their gait assessed using three - dimensional motion analysis . -
pubmed
anti-1 - Amino-3 -[( 18 ) F ] fluorocyclobutane-1 - carboxylic acid ( anti
-[( 18 ) F ] FACBC ) was shown to have a high
tumor / brain ratio ( 8) , and anti
-[( 18 ) F ] FACBC has been studied in
humans with PET
tumor imaging ( 9 ) . -
pubmed
Adjuvant
carboplatin and
gemcitabine combination chemotherapy postamputation in
canine appendicular osteosarcoma . -
pubmed
BACKGROUND :
Appendicular osteosarcoma (
OSA ) , the most common
bone tumor in
dogs , is typically treated by amputation and adjuvant chemotherapy . -
pubmed
Evidence from studies in
mice suggests that
gemcitabine has activity against
OSA in vivo . -
pubmed
ANIMALS : Fifty
dogs with histologically confirmed
appendicular OSA . -
pubmed
Dogs with proximal humeral
OSA had a shorter median DFI ( P = .04 ) compared with
dogs with
OSA in other locations . -
pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : These results are comparable to those reported for
carboplatin monotherapy indicating that the addition of
gemcitabine to
carboplatin in
dogs with
appendicular OSA does not appear to improve outcome . -
pubmed
Successful cochlear implantation in a
patient with
MNGIE syndrome . -
pubmed
Abstract A 28 - year - old
woman with
mitochondrial neurogastrointestinal encephalomyopathy (
MNGIE syndrome ) undergoing evaluation for multichannel cochlear implantation is described . -
pubmed
Characterization of spontaneous
subclavian steal phenomenon in a female
rhesus macaque (
Macaca mulatta ) . -
pubmed
Although
SSP is a common echographic finding in
humans , the phenomenon occurs only rarely in
animals ; consequently its physiologic features have not been reported previously . -
pubmed
Here we describe the clinical and morphologic features of a spontaneous left
SSP that was an incidental finding in an 18 - y - old female
rhesus macaque (
Macaca mulatta ) . -
pubmed
Populations of
tetraploid D. - pubmed
An antimicrobial , antithrombotic lock solution reduced catheter - related
bloodstream infections in
patients receiving dialysis . -
pubmed
BACKGROUND : Several agents are available to treat
osteoporosis while addressing
patient - specific medical needs . -
pubmed
Individuals ' residual risk to severe
fracture may require changes in treatment strategy . -
pubmed
Our study on a series of five consecutively taken bone biopsies from an
osteoporotic individual over a six - year period analyzes changes in cellular characteristics , bone microstructure and mineralization caused by a therapy switch from an antiresorptive (
bisphosphonate ) to a dual action bone agent (
strontium ranelate ) . -
pubmed
[ Long - term prognosis in
patients with acute non - ST - segment elevation
myocardial infarction depending on dynamics of tissue myocardial dopplerography ] . -
pubmed
MATERIAL AND METHODS : MTD echocardiography was conducted in 88 non - ST elevation
AMI ( mean age 58.0 - 9.8 years ) and 34 healthy
volunteers ( mean age 58.0 + /- 9.8 years ) . -
pubmed
CONCLUSION : The treatment of non - ST elevation
AMI reduces the number of
patients with a diffuse decrease of MTD values and elevates the number of
patients with asymmetric decrease of MTD and unchanged MTD . -
pubmed
In vivo imaging of stepwise
vessel occlusion in
cerebral photothrombosis of
mice by
19F MRI . -
pubmed
In the present study we compared
( 19 ) F MRI with
iron - enhanced MRI in
mice with
photothrombosis ( PT ) at 7 Tesla . -
pubmed
By sequential administration of two chemically shifted PFC compounds 0 and 2 hours after illumination the different spatial distribution of the
( 19 ) F markers (
infarct core / rim ) could be visualized in the same
animal . -
pubmed
[
Antisynthetase syndrome : a retrospective study of 14
patients ] . -
pubmed
PATIENTS AND METHODS : Fourteen
patients with
antisynthetase syndrome followed - up between 1997 and 2009 were included . -
pubmed
Seven
patients had
myositis . -
pubmed
After a mean follow - up of 64 months , nine
patients improved , four stabilized and one
patient died after lung transplantation , required for
pulmonary hypertension . -
pubmed
We reviewed previous studies of
subjects in a
prodromal stage of
psychosis and tested cingulate volume changes during the transition to
psychosis . -
pubmed
METHODS : A cross - sectional MRI study of manually traced cingulate gray - matter volumes in 37
individuals with an at risk mental state ( ARMS ) for
psychosis , 23
individuals with a first - episode
psychosis (
FEP ) , and 22 healthy controls ( HC ) was performed using a 1.5 T MRI - scanner . -
pubmed
RESULTS : Compared to HC ,
subjects with an
ARMS had significantly reduced left caudal anterior cingulate cortex volume ( p & lt ; 0.027 ) . -
pubmed
MATERIAL AND METHODS : We included in the study 1005
patients with
coronary artery disease and normal serum
creatinine . -
pubmed
CONCLUSIONS : In our study we found a very high prevalence of
CKD up to 61 % in elderly
patients with
coronary artery disease and normal serum
creatinine . -
pubmed
A preliminary investigation of corpus callosum and anterior commissure aberrations in aggressive
youth with
bipolar disorders . -
pubmed
METHOD : DTI was used to investigate WM in 10
youth ( 7 - 17 years of age ) with
BPD and 10 typically developing age - matched controls . -
pubmed
CONCLUSIONS : These results contribute to a growing literature implicating a role for the genu of the CC in
BPD and are the first to report WM variations in the AC of
children with
BPD . -
pubmed
Here , we enabled global processing in
patients with
simultanagnosia using a psychophysical technique , which allowed us to bias stimuli such that they are processed predominantly by the intact ventral visual pathway . -
pubmed
Minor complications were
skin reaction only in 2
patients ( 6 % ) . -
pubmed
The aim of this retrospective study was to present our own experience with 5
children affected with
C - RE , emphasizing the differences in clinical picture and low sensitivity of ultrasound images . -
pubmed
PATIENTS AND METHODS : A 67 - year - old
woman was hospitalized for
flank pain ; imaging studies revealed a 6.5 - cm mass in the right kidney . -
pubmed
papillary RCC with sarcomatoid transformation ) is important for predicting
patient prognosis . -
pubmed
Even though not explored in this manuscript , the impact that the results presented here may have on the development of
gastritis , warrant further research to understand the underlying mechanisms of the relationship between
H. - pubmed
Careful long - term follow - up is essential even in
patients with benign
pheochromocytoma . -
pubmed
Vitamin D levels and
insulin resistance in
children born with severe growth restriction . -
pubmed
In conclusion , at prepuberty severely in utero growth restricted
children have increased
birth weight dependent levels of
25 ( OH ) D , which might exert a regulatory role on beta - cell function . -
pubmed
Relapse of
herpes encephalitis induced by
temozolomide - based chemoradiation in a
patient with
malignant glioma . -
pubmed
Careful observation for
HSE is necessary when administering chemoradiation to
patients with a history of
HSE . -
pubmed
The therapeutic drug monitoring of
paroxetine could be used to optimize the pharmacological treatment of
depressed patients . -
pubmed
Moreover , under the optimal fermentation conditions in a 7.5 l fermenter , the MCR production of
MX3004 reached the maximum of 263 U / ml , which was increased by 484 % compared with the parent
strain . -
pubmed
METHODS : A total of 1,681
patients were diagnosed preoperatively with unilateral
inguinal hernia . -
pubmed
All
patients underwent laparoscopic
inguinal hernia transabdominal preperitoneal ( TAPP ) repair . -
pubmed
Patients with an evident occult
hernia received immediate repair . -
pubmed
Patients with a smaller beginning or incipient
hernia were followed . -
pubmed
All
patients with an incipient
hernia were followed . -
pubmed
METHODS AND MATERIALS : We selected
patients treated for
localized prostate cancer with brachytherapy , combination therapy with external beam radiotherapy , and adjuvant
androgen deprivation therapy as prescribed by our Mount Sinai risk stratification and treatment algorithm . -
pubmed
CONCLUSIONS : Brachytherapy , as administered via the Mount Sinai algorithm , remains an efficacious and benign treatment option for
patients with localized
prostate cancer of all risk groups . -
pubmed
Bovine colostrum improves intestinal function following formula - induced
gut inflammation in preterm
pigs . -
pubmed
BACKGROUND & amp ; AIMS : Only few hours of formula feeding may induce proinflammatory responses and predispose to
necrotizing enterocolitis (
NEC ) in preterm
pigs . -
pubmed
CONCLUSIONS :
Bovine colostrum restores intestinal function after initial formula - induced
inflammation in preterm
pigs . -
pubmed
Further studies are required to test if
bovine colostrum may also benefit
preterm infants during the challenging transition from total parenteral nutrition to enteral nutrition , when
human milk is unavailable . -
pubmed
METHODS : A total of 118 429
subjects without
diabetes ( 70 980
men and 47 449
women ) , aged 17 - 90 years ( mean age 39.6 years ) , were enrolled in this study and followed for a mean duration of 3.1 years . -
pubmed
Patients with a poor prognosis histologic subtype or
peritoneal carcinosis were excluded . -
pubmed
One hundred ninety - nine
patients had
squamous carcinoma , and 38 had
adenocarcinoma / adenosquamous
lesions . -
pubmed
The anti -
obesity effects of the dietary combination of fermented
red ginseng with levan in high fat diet
mouse model . -
pubmed
In this study , to evaluate the anti -
obesity effects of fermented
red ginseng ( FG ) , levan ( L ) , and their combination ( FGL ) , we investigated their effects on the weights of body , liver and white adipose tissue , lipid profiles , and biomarkers for
insulin resistance in high fat diet ( HFD)-induced
obese C57BL/6J male
mice . -
pubmed
After 11 weeks feeding , FGL showed significantly lower
body weight and fat mass with decreasing food efficiency ratio than the HFD control
mice . -
pubmed
Nevertheless , there are cases of successful ECMO application in
patients with
multiple trauma and
hemorrhagic shock or
head trauma and
intracranial hemorrhage . -
pubmed
We successfully applied ECMO in a 65 - year - old
woman with acute life - threatening
respiratory failure due to diffuse massive
pulmonary hemorrhage secondary to
granulomatosis with polyangiitis , manifested as severe
pulmonary - renal syndrome . -
pubmed
RESULTS : 20
subjects were diagnosed with well - differentiated
liposarcoma (
WLS ) , 16
myxoid liposarcoma (
ML ) , 7
pleomorphic liposarcoma (
PL ) , and 5
de - differentiated liposarcoma (
DLS ) . -
pubmed
This is the first report to identify Group A
Streptococcus emm type-89 as a cause of
tonsillopharyngitis in Beijing , China . -
pubmed
Deaths occurred in 7
patients . -
pubmed
PATIENTS AND METHODS : We retrospectively evaluated
patients with intramural
pseudocysts seen at our institution over the past 6 years . -
pubmed
Depending upon the symptoms , their control with the conservative medical therapy and procedural consent , the
patients underwent EUS guided single time aspiration of the
pseudocyst or transmural drainage or transpapillary drainage or surgery . -
pubmed
RESULTS : A total of 9
patients with intra mural
pseudocysts ( male : n = 8 ; mean age + - SD : 39.3 + - 8.0 years ; age range : 24 - 54 years ; five
patients having chronic and four
patients having acute
pancreatitis ) were studied . -
pubmed
The
pseudocysts were located in the wall of the second part of the duodenum in five
patients , in the gastric wall in three
patients and in the lower esophageal wall in one
patient . -
pubmed
All
patients had
abdominal pain on presentation . -
pubmed
Along with
pain the
patients with duodenal intramural pseduocysts also had symptoms suggestive of
gastric outlet obstruction ( 3 ) or
jaundice ( 1 ) . -
pubmed
Transcriptomic analysis of
Prunus domestica undergoing hypersensitive response to
plum pox virus infection . -
pubmed
One variety of
Prunus domestica , named ' Jojo ' , develops a hypersensitive response to
viral infection . -
pubmed
The combination of next - generation sequencing and a
Prunus variety that develops a hypersensitive response to
PPV infection provided an opportunity to study the factors involved in this plant defense mechanism . -
pubmed
BACKGROUND : Macroscopic cytoreductive surgery and hyperthermic intrathoracic chemotherapy perfusion ( HITHOC ) is a new multimodal approach for selected
patients with primary and secondary
pleural tumors , which may provide the
patient with better local
tumor control and increased overall survival rate . -
pubmed
Only two
patients ( 10 % ) showed an
impairment of coagulation in postoperative laboratory analysis . -
pubmed
Growth retardation and
growth hormone deficiency in
patients with
Ataxia telangiectasia . -
pubmed
BACKGROUND :
Ataxia telangiectasia (
A - T ) is a devastating
human recessive disorder characterised by progressive
cerebellar ataxia ,
immunodeficiency , genetic instability , and
cancer susceptibility . -
pubmed
In addition , many
patients suffer from
growth failure . -
pubmed
Recent recognition of these effector cells in immune regulations , host defense against
bacteria and virus , and
autoimmune diseases entices increased interest in studying these cells . -
pubmed
Plants treated with 5 mM
ALA or 50 microM
OF exhibited differential herbicidal symptoms as characterized by white and brown
necrosis , respectively , with substantial increases in cellular leakage and
malondialdehyde production . -
pubmed
Effect of
neurotoxic lesion of pedunculopontine nucleus in nigral and striatal redox balance and motor performance in
rats . -
pubmed
RESULTS : During the exponential growth phase ( log ) of bacterial
strains , a lineal correlation between luminous activity vs biomass was observed ( R(2 ) = 0.985 , 0.976 , 0.981 ) for
E. - pubmed
Posttransplantation diabetes mellitus (
PTDM ) is a major complication after renal transplantation due to its negative impact on
patient and graft survival , and affects up to 40 % of renal transplant recipients . -
pubmed
This review will discuss the significance of the standard diagnostic criteria for
DM in
patients after renal transplantation without prior
DM . -
pubmed
The ketogenic diet ( KD ) is an effective alternative treatment for
refractory epilepsy in
children , but the mechanisms by which it reduces
seizures are poorly understood . -
pubmed
METHODS : Ten
patients with plasma cell - rich chronic inflammatory conditions of the oral mucosa were identified ( seven -- plasma cell
mucositis and three -- non - specific diffuse
oral mucosal inflammation with
ulceration ) . -
pubmed
Hence ,
ethidium bromide was used in a
rat model to evaluate the positive effects of
Dl-3 - n - butylphthalide in
demyelinating diseases . -
pubmed
CONCLUSIONS : In vitro addition of
idarucizumab to plasma samples containing
dabigatran fully neutralizes the drug , and facilitates the use of routine coagulation assays to allow the diagnosis of
hemostasis disorders that may be concurrently present in
patients taking
dabigatran . -
pubmed
Here we address this question by testing 32
adults with
generalized anxiety disorder ( 15
GAD only and 17 comorbid
MDD ) and 25 healthy controls ( HC ) using multimodal MRI ( structure , diffusion and functional ) and automated hippocampal segmentation . -
pubmed
We found that only the
mice that lacked the interstitial region developed
prostate adenocarcinomas marked by poor differentiation and epithelial - to - mesenchymal transition . -
pubmed
RATIONALE :
Obstructive sleep apnea (
OSA ) is common in
patients with
coronary artery disease (
CAD ) , many of whom do not report
daytime sleepiness . -
pubmed
First - line treatment for symptomatic
OSA is continuous positive airway pressure ( CPAP ) , but its value in
patients without
daytime sleepiness is uncertain . -
pubmed
OBJECTIVES : To determine the effects of CPAP on long - term adverse cardiovascular outcome risk in
patients with
CAD with nonsleepy
OSA . -
pubmed
Consecutive
patients with newly revascularized
CAD and
OSA (
apnea -
hypopnea index & gt;=15 / h ) without
daytime sleepiness ( Epworth Sleepiness Scale score & lt;10 ) were randomized to auto - titrating CPAP ( n = 122 ) or no positive airway pressure ( n = 122 ) . -
pubmed
CONCLUSIONS : Routine prescription of CPAP to
patients with
CAD with nonsleepy OSA did not significantly reduce long - term adverse cardiovascular outcomes in the intention - to - treat population . -
pubmed
Inpatients aged 0 to 9 years experienced higher rates of airway and respiratory complications , peaking at an odds ratio of 7.5 ( 95 % CI , 3.1 - 18.2 ) for
airway complications in the group aged 0 to 11 months . -
pubmed
Fetal alcohol syndrome (
FAS ) is a condition resulting from excessive drinking by pregnant
women . -
pubmed
In
ethanol - treated
mice , there was a reduction in brain size and decreased neuronal cell number in the cortex , and also
cognitive impairment . -
pubmed
MATERIALS AND METHODS : At 3 T , relative pCASL labeling efficiency was experimentally assessed in five
subjects by measuring the signal intensity of blood in the popliteal artery just distal to the labeling plane immediately following pCASL labeling or control preparation
pulses , or without any preparation
pulses throughout separate
ischemia - reperfusion paradigms . -
pubmed
In a separate cohort of 10
subjects , pCASL and PASL sequences were used to measure reactive
hyperemia perfusion dynamics . -
pubmed
PARTICIPANTS : Postmenopausal
women diagnosed with
hip fracture ( n = 335 ) and matched controls without
fracture ( n = 335 ) . -
pubmed
This case demonstrates the usefulness of genomic analysis in establishing the diagnosis of
DBA in
patients with a nonclassical presentation of the disease . -
pubmed
Although the incidence of
cardiovascular diseases classically associated with
human immunodeficiency virus (
HIV ) has decreased considerably with antiretroviral therapy , cardiovascular risk , and especially
ischemic heart disease , are higher in HIV - infected patients than in uninfected individuals . -
pubmed
Currently , it is not uncommon to find
HIV patients with
acute coronary syndrome and , given the important pharmacokinetic interactions of antiretroviral drugs , it is important to know which cardiovascular treatments are safe in this group of patients . -
pubmed
All these issues are discussed in this review , which aims to aid clinical cardiologists faced with
HIV patients with
ischemic heart disease or with high cardiovascular risk in daily clinical practice . -
pubmed
This study was aimed at assessing the role of Posthorax support vest ( Epple , Inc. , Vienna , Austria ) in the prevention of sternal complications and the improvement of anatomical healing in
patients at high risk for mechanical
sternal dehiscence after cardiac surgery by mean of median sternotomy . -
pubmed
METHODS : A prospective , randomized , study was performed and 310
patients with predisposing factors for
sternal dehiscence after sternotomy for cardiac surgery were included . -
pubmed
RESULTS :
Patients using vest demonstrated a lower incidence of mechanical sternal complications , a better anatomical sternum healing , lower hospital stay , no re - operations for
sternal dehiscence before discharge and lower re - admissions for mechanical sternal complication . -
pubmed
Atomoxetine treatment for
children and
adolescents with
Attention - Deficit / Hyperactivity Disorder (
ADHD ): a comprehensive meta - analysis of outcomes on parent - rated core symptomatology . -
pubmed
Attention - Deficit / Hyperactivity Disorder (
ADHD ) impacts a significant number of
children and adolescents and often leads to deleterious
functional impairment . -
pubmed
METHODS : A total of 254 male
patients with
CAD and 122 male controls were recruited for this study . -
pubmed
Zebra chip disease (
ZC ) is an emerging disease of
potato in which tubers are produced with striped
necrotic patterns that make them unmarketable . -
pubmed
The effect of
L - thyroxine substitution on oxidative stress in early - stage
diabetic nephropathy patients with
subclinical hypothyroidism : a randomized double - blind and placebo - controlled study . -
pubmed
PURPOSE : To study oxidative stress status of early
type 2 diabetic nephropathy (
DN )
patients with
subclinical hypothyroidism (
SCH ) and to assess effect of
L - thyroxine therapy on the oxidative stress in these
patients . -
pubmed
A total of 48
patients with early
type 2 DN were included as Euthyroid group , and 92 early type 2 DN with SCH were selected and randomly assigned to
L - thyroxine treatment group ( LT4 group ) and placebo group ( SCH group ) . -
pubmed
CONCLUSION : Oxidative stress is greater in the DN
patients with
SCH , and
SCH may exacerbate
kidney injury in early
DN patients . -
pubmed
The
LT4 treatment may decrease the oxidative stress and attenuate
renal injury in
DN patient with
SCH . -
pubmed
Age- and gender - related hemorheological alterations in intestinal
ischemia - reperfusion in the
rat . -
pubmed
Platelet count elevated in the younger male and older female I / R
animals . -
pubmed
Only standardized parasitological tools , supplemented by epidemiological analysis , will be able to clarify whether parasite carriage could be connected to
IBS and its status as a
human pathogen . -
pubmed
Therapy study was conducted in triple - negative
breast cancer - bearing
BALB / c mice . -
pubmed
Application to
Bartonella henselae infection RNAi screening data yielded an eight node network largely in agreement with previous works , and revealed novel binary interactions of direct impact between established components . -
pubmed
Most
animal models of
diabetic retinopathy are
hyperglycaemia - only models that do not account for the significant role that
inflammation plays in the development of the disease . -
pubmed
In the present study , we present data on the establishment of a new
animal model of
diabetic retinopathy that incorporates both
hyperglycaemia and
inflammation . -
pubmed
Oral treatment with CAW also attenuates hippocampal
mitochondrial dysfunction in these
animals . -
pubmed
BACKGROUND : Besides mammography , breast ultrasound is the most important imaging modality for
women with suspected
breast cancer . -
pubmed
Exposing
mice to patient 's refluxates induced expansion of multi - layered glandular structures and development of columnar
metaplasia at the squamo - columnar junction . -
pubmed
Our findings support the hypothesis that in
humans ,
BE arises from non - squamous cells residing in submucosal gland ducts and that induction of intestinal type of
metaplasia is most effectively induced by
glycine - conjugated
bile acids . -
pubmed
Patients with & lt;90 - day follow - up , intraoperative graft preparation with an antibiotic other than
vancomycin , or previous ipsilateral
knee infection were excluded . -
pubmed
Distribution and relevance of
Dientamoeba fragilis and Blastocystis species in
gastroenteritis : results from a case - control study . -
pubmed
The actual role of
Dientamoeba fragilis and Blastocystis in patients with
gastrointestinal symptoms is still under debate . -
pubmed
In the present study , a real - time PCR for Blastocystis was performed on 1374 case samples and 1026 control samples from the multicenter
gastroenteritis case - control study previously tested for
D. - pubmed
METHODS :
Patients with colorectal
adenocarcinoma (
ADEC ) , neuroendocrine
carcinoma (
NEC ) ,
MANEC and ANED were identified diagnosis from 2010 to 2014 using the Surveillance , Epidemiology , and End Results ( SEER ) database . -
pubmed
Deep inspirations attenuate
postprandial airway inflammation in college - aged
adults with elevated baseline exhaled
nitric oxide : A pilot study . -
pubmed
The role of social support on the effects of stress and
depression on African American
tobacco and
alcohol use . -
pubmed
West Nile Virus and Related Flavivirus in
European Wild Boar (
Sus scrofa ) , Latium Region , Italy : A Retrospective Study . -
pubmed
BACKGROUND : A retrospective sero - survey for evidence of
West Nile virus ( WNV ) infection in European wild boar (
Sus scorfa ) was conducted in the Latium region , Italy , on stored serum samples of the period November 2011 to January 2012 . -
pubmed
Postoperative Adjuvant Transarterial Infusion Chemotherapy with FOLFOX Could Improve Outcomes of
Hepatocellular Carcinoma Patients with Microvascular Invasion : A Preliminary Report of a Phase III , Randomized Controlled Clinical Trial . -
pubmed
BACKGROUND : Microvascular invasion ( MVI ) is a risk factor for
tumor recurrence after hepatectomy in
hepatocellular carcinoma (
HCC )
patients . -
pubmed
OBJECTIVE : This study aimed to investigate the efficacy and safety of postoperative adjuvant transarterial infusion chemotherapy ( TAI ) with the FOLFOX regimen for
HCC patients with MVI . -
pubmed
CONCLUSIONS : Adjuvant TAI after hepatectomy may bring survival benefits to
HCC patients with MVI . -
pubmed
Case : We describe a case of a 62 - year - old female
patient admitted with acute
ST - elevation myocardial infarction (
STEMI ) treated by primary coronary intervention ( primary PCI ) with a drug - eluting stent placement . -
pubmed
Patients and Methods : We measured the following parameters of
DDH and contralateral normal hip ( CNH ) of proximal morphology of femurs on 65
patients with unilateral
Crowe type IV DDH ( 30 hips with no false acetabulum ( type IVA ) and 35 hips with a false acetabulum ( type IVB ) ) in our hospital between September 2009 and July 2019 on anteroposterior radiographs : the widths of medullary canals at 20 mm above the center of lesser trochanter ( CLT ) , 20 mm below the CLT and the isthmus . -
pubmed
Although there are effective
nucleoside analogs to treat
HSV ,
VZV , and
HCMV disease ,
herpesvirus infections continue to contribute to significant morbidity and mortality . -
pubmed
Treatment of
HCMV with
GCV requires close monitoring particularly in patients with
impaired renal function and there are no approved treatments for congenital
HCMV infections . -
pubmed
New therapeutic options to control
cytomegalovirus reactivation in bone marrow and stem cell transplant
patients are needed to improve
patient outcome . -
pubmed
Working memory ( WM ) is known to be impaired in
patients with
stroke experiencing
unilateral spatial neglect (
USN ) . -
pubmed
Fourteen USN first - event
stroke patients with right - hemisphere damage were tested in two different WM experiments using long and short retention intervals and an analog response scale . -
pubmed
This study aimed to estimate time to recovery and to determine predictors of time to recovery among
children aged 6 - 59 months with severe
acute malnutrition . -
pubmed
An accurate understanding of why
zoonoses such as
SARS - CoV-2 are emerging at an increased rate , is vital to prevent future pandemics from the approximately 700,000 viruses with zoonotic potential . -
pubmed
After 7 years , 80.8 % of the
patients at risk had developed
nephropathy and 75.7 % had developed
neuropathy . -
pubmed
The lungs and heart were examined morphologically in 24
persons who had died from
cirrhosis of the liver in the edematous - ascitic stage . -
pubmed
Secondary - compensatory changes in the contractile function of the myocardium of the right parts of the heart in response to increase of pressure in the pulmonary artery in
patients with
cirrhosis of the liver were proved to occur . -
pubmed
Cytotoxic effects of
procaine ,
lignocaine and
bupivacaine were investigated on cultures of
Chinese hamster lung fibroblasts . -
pubmed
Ultrastructural pathology of peripheral nerves in
patients with
diabetic neuropathy . -
pubmed
Sural nerve lesions in
patients with clinically manifest
diabetic neuropathy were investigated electron microscopically . -
pubmed
Myelinated nerve fibers were reduced in all the
diabetic patients . -
pubmed
These results indicated that the
peripheral nerve lesions in
human diabetics were mainly due to metabolic impairment of nerve fibers , accompanying dysmetabolism of Schwann cells and
diabetic microangiopathy , and that these changes proceeded independently . -
pubmed
Since 1959 , 51
patients underwent open heart surgery for correction of an acute dissecting
aneurysm of the ascending aorta . -
pubmed
Upon admission , 33
patients were severely
hypotensive or in progressive
heart failure . -
pubmed
Acute
aortic insufficiency was found in 24
patients , and
hemiplegia or
hemiparesis in four . -
pubmed
Nine
patients died within the early postoperative course from uncontrollable
hemorrhage ( four ) , further dissection ( three ) and
myocardial infarction ( two ) . -
pubmed
Within the first year after surgery , another five
patients died from
acute aortic dissection ( two ) ,
pseudomonas infection causing
rupture of the proximal graft anastomosis ( one ) and
myocardial infarction ( two ) . -
pubmed
T - lymphocytes response to
Friend virus - induced tumour cell lines in
mice of
strains congenic at H--2 . -
pubmed
This case - control study sought to determine whether protection against clinically significant
rotavirus diarrhea in
children aged 4 - 35 months correlated with titers of serum neutralizing antibody and , if so , whether this protection was serotype - specific . -
pubmed
[ The physiotherapy of
patients with
lumbar spinal osteochondrosis in the early period after surgical treatment ] . -
pubmed
Altogether 130
patients with associated
lumbar spinal osteochondrosis and the
radicular syndrome were placed under observation after operation in the form of laminectomy and removal of
hernia of intervertebral discs . -
pubmed
Renal transplantation is regularly successful in infancy and should be considered an integral component of the therapy for any
child with
chronic renal failure . -
pubmed
Renal handling of free
sialic acid in normal
humans and
patients with
Salla disease or
renal disease . -
pubmed
The renal handling of free
sialic acid , a negatively charged
sugar , was investigated in normal
humans and in
patients with
impaired sialic acid metabolism or
impaired renal function . -
pubmed
In other
patients with different degrees of
renal insufficiency , free
sialic acid clearance varied directly with
creatinine clearance , indicating filtration of this
sugar by renal glomeruli . -
pubmed
In
patients with
renal Fanconi syndrome , the urinary excretion of free
sialic acid was independent of the severity of the generalized tubular defect , indicating that
sialic acid was not reabsorbed by renal tubular cells . -
pubmed
In addition , three of eight
patients with
Salla disease , a storage disorder due to impaired lysosomal transport of free
sialic acid , were found to have reduced
creatinine clearances , but all
Salla disease patients had entirely normal renal tubular function . -
pubmed
Effects of
salicylate on chondrocytes from
osteoarthritic and contralateral knees of
dogs with unilateral anterior cruciate ligament transection . -
pubmed
However , chondrocytes from the contralateral knees of
dogs with
unilateral OA were notably resistant to the effects of
salicylate . -
pubmed
Intraoperative esophageal manometry has not been correlated with early postoperative extended esophageal pH monitoring ( EEpHM ) in
children with
gastroesophageal reflux . -
pubmed
Forty - two
patients with a clinical diagnosis of
bacterial conjunctivitis were enrolled in a randomized , double - blind trial . -
pubmed
A phase I trial of
chlorambucil administered in short
pulses in
patients with advanced
malignancies . -
pubmed
Thirty
patients with advanced
cancer were entered in six dose levels : 36 , 48 , 60 , 84 , 108 , and 144 mg / m2 . -
pubmed
Central nervous system toxicity was dose limiting , occurring in 5 of 6
patients at 144 mg / m2 . -
pubmed
Leukopenia ( 3
patients ) and
thrombocytopenia ( 2
patients ) were mild . -
pubmed
One
patient with colorectal
carcinoma had a minor response , and two
patients with
non - small cell lung cancer had stable disease . -
pubmed
Statistical assessment of perceptual CT scan ratings in
patients with
Alzheimer type dementia . -
pubmed
Our case relates to
giant cell arteritis presenting as
pulmonary artery obstruction in a
patient without
polymyalgia rheumatica or extensive aortic or proximal great vessel involvement . -
pubmed
In 115
patients with
chronic lymphocytic leukemia (
CLL ) , grouped according to the staging system as proposed by Rai et al . -
pubmed
[ Central nervous system of a 12 mm
human embryo with complete cyclops : a case of
holoprosencephaly ] . -
pubmed
A radiological study of 50
patients with
thoracic Scheuermann ' s disease revealed two types of lateral
spinal curvature . -
pubmed
We studied a 17 - year - old
girl with subacute necrotizing
encephalomyelopathy (
Leigh syndrome ) . -
pubmed
Induction of RNA "
tumor " viruses by
5 - iodo-2 '- deoxyuridine in
mouse fibroblasts is stimulated 5- to 25 - fold by glucogenic adrenal corticosteroids . -
pubmed
Congenital otocephalus in a
lamb . -
pubmed
[ Homotransplantation of preserved kidney by
hypothermia and hyperbaric
oxygen in
man ] . -
pubmed
The effect of
hypocapnia on the level of
halothane anesthesia in
man . -
pubmed
Passive transfer between experimental animals of
hypersensitivity to
Aedes aegypti bites . -
pubmed
It is concluded that the
reindeer can maintain its body temperature also in severe
cold although the extremities show characteristics of
heterothermia . -
pubmed
Twelve
patients with drug resistant ventricular ( 3 ) or supraventricular ( accessory pathway ( 2 ) ,
atrial flutter ( 3 ) ,
junctional tachycardia ( 3 ) ,
supraventricular tachycardia ( 1 )
tachyarrhythmias are reported in whom , after electrophysiological analysis of the individual
tachycardia , a specially designed stimulation system was implanted . -
pubmed
After pacemaker implantation we observed a significant decrease in incidence and/or duration of
tachycardic episodes in all
patients . -
pubmed
In two
patients atrial pacing ( 80 and 90 / min ) suppressed
tachycardias completely . -
pubmed
These stimulatory effects of SA96 and
D - PA on the humoral immune responses were also not dose - dependent , and the maximum effects of
SA96 were observed with 10 mg / kg / day , as in the case of adjuvant - induced
arthritis in
rats . -
pubmed
Withdrawal and subsequent reintroduction of EN confirmed that there was worsening of
left ventricular dysfunction in the other 3
subjects . -
pubmed
At maximal exercise , cardiac and
stroke volume indexes increased by 29 and 18 % , respectively ( p less than 0.01 ) , after EN ; the duration of exercise increased in 7 of the 10
subjects after acute therapy and this was maintained on a long - term basis . -
pubmed
Amitriptyline in
children with
major depressive disorder : a double - blind crossover pilot study . -
pubmed
Cerebral blood flow and cerebral metabolism in
children following cardiac surgery with deep
hypothermia and
circulatory arrest . -
pubmed
Between November 1975 and June 1977 , 49
children underwent repair of complicated
cardiac defects with the aid of deep
hypothermia . -
pubmed
Nine
children died ( 18 % ) due to early postoperative
heart failure . -
pubmed
A decisive cause of
death in terms of important
cardiovascular defects , which were either unknown or not correctable at the time of repair , was found in 6
patients . -
pubmed
Children with complicated forms of
congenital heart disease requiring an extensive repair were overrepresented among those who died . -
pubmed
Hence , there was an excess in the duration of bypass among nonsurvivors ( p less than 0.01 ) whereas the
patient 's age at operation , the use of
circulatory arrest and the duration of
aortic occlusion had no bearing on operative mortality . -
pubmed
min-1 in 3
children with long periods of
circulatory arrest . -
pubmed
However , in 3
children operated with
circulatory arrest , difficulties in performing more delicate motor activities were noted by the parents . -
pubmed
[ Determination of the development of
psychotic dependence to drugs in small
animals . -
pubmed
To develop a screening method for
psychic dependence liability of the drugs ,
morphine- and
cocaine - directed drinking behavior was studied in
mice . -
pubmed
When the
animals were forcedly given drugs as drinking solution total intake and the gain of
body weight was suppressed in proportion to the concentration of the drugs . -
pubmed
[ A case of
neonatal meningitis caused by group B streptococcus (
S. - pubmed
Hypothalamic obesity in male
rats : comparison of parasagittal , coronal , and combined knife cuts . -
pubmed
In 124
children , age 6 months to 6 years , suspected to have
asthma the non - electrostatic spacer delivered a mean total dose of
budesonide aerosol of 39 % of the nominal dose , which was significantly higher than the Babyhaler ( 28 % ) , the Nebuhaler ( 21 % ) , and the AeroChamber ( 19 % ) . -
pubmed
Up to 85 % of
patients with
bronchogenic carcinoma are inoperable at the time of diagnosis and treatment remains largely palliative . -
pubmed
Patients with inoperable
lung cancer and obstruction of central airways should undergo initial endobronchial therapy followed by conventional chemo - radiotherapy . -
pubmed
Functional neuroimaging with positron emission tomography previously demonstrated reduced caudate
glucose metabolism in virtually all symptomatic
patients with
Huntington ' s disease (
HD ) . -
pubmed
Single - photon emission computed tomography studies of brain blood flow also have shown
caudate abnormalities in
patients with
HD . -
pubmed
The present study compared these two functional imaging modalities in 6
patients with
HD who had been symptomatic for fewer than 5 years . -
pubmed
The role of this technique in the management of
HIV positive
patients with
empyema is discussed . -
pubmed
Appropriateness of serologic tests and parenteral antibiotic therapy for
patients with presumed
Lyme disease . -
pubmed
This 32 - year - old
patient with
hairy cell leukaemia demonstrated extensive bony involvement in a pattern not previously described . -
pubmed
Putative
bovine B cell lineage tumor in
sporadic bovine leukosis . -
pubmed
A
tumor cell line ,
BLC3 , established from calf C924 in
nude mice was examined for immunophenotype , DNA rearrangement of immunoglobulin ( Ig ) genes and expression of cellular oncogenes c - abl , c - myc and c - myb . -
pubmed
Taken together , our data show that the calf type of
SBL found in these two calves is induced by immature pre - B cells , including
tumor cell line
BLC3 established in
nude mice . -
pubmed
Renal sonography detected only 6 of 16
patients with
pyonephrosis ( specificity 96 % , sensitivity 38 % , accuracy 72.5 % ) . -
pubmed
BACKGROUND : In severe
human heart failure , an increase in frequency of stimulation is accompanied by a reduced force of contraction in vivo and in vitro . -
pubmed
Eight unexpected
cardiorespiratory arrests occurred in seven
children ( 9 % ) . -
pubmed
Chronic
congestive heart failure was noted in 10 % of
patients . -
pubmed
Thirty
children died , 10 with significant
cardiac dysfunction . -
pubmed
Eighteen
patients with
Paget ' s disease of bone were randomly allocated to three therapeutic groups receiving respectively 600 , 800 , and 1200 mg / day
tiludronate for five days . -
pubmed
Fifty per cent of
patients treated by a dose of 1200 mg / day reported
gastrointestinal disturbances , however , making this dosage unsuitable for clinical practice . -
pubmed
Liver scintigraphy using
99mTc - GSA was performed on 13
patients with
liver disease . -
pubmed
Steroid - induced sex determination at incubation temperatures producing mixed sex ratios in a
turtle with
TSD . -
pubmed
Previous studies have shown that exogenous
steroid hormones can affect sex determination in
reptiles with temperature - dependent sex determination (
TSD ) . -
pubmed
Creatinine and
urea clearance during continuous veno - venous haemofiltration in
critically ill patients . -
pubmed
Urea and
creatinine clearances achieved using continuous veno - venous haemofiltration were calculated in 16
critically ill patients , during 50 episodes of filtration . -
pubmed
A retrospective study of
patients hospitalized for treatment of
cystic lesions associated with retained third molars during a 10 - year period showed a total of 32
cystic lesions in 25
patients . -
pubmed
These data should raise the question related to suprarenal response to acute or prolonged stresses , such as surgical operations or
shock in
women using Norplant implants . -
pubmed
Spindle and motoneuronal contributions to the phase advance of the
human stretch reflex and the reduction of
tremor . -
pubmed
The most common underlying disease was
epidermoid carcinoma ( 82 percent ) , the average
patient age was 55 years , and the average length of follow - up was 13.5 months . -
pubmed
Postoperatively , two
patients experienced
fracture at the donor site ( 12 percent ) , and three patients ( 18 percent ) had hardware related problems such as exposure ,
infection , or both . -
pubmed
Low - risk
human papillomavirus types 6 and 11 associated with
carcinomas of the genital and upper aero - digestive tract . -
pubmed
BACKGROUND :
Human papillomavirus (
HPVs ) types 6 and 11 , are frequently found in
non - malignant anogenital condylomas and
laryngeal papillomas . -
pubmed
RESULTS : Four invasive
carcinomas containing
HPV 6 or 11 could be detected ( 2.4 % ) by Southern blot technique . -
pubmed
HPV 6 DNA was found in a
penile carcinoma , a
groin carcinoma , and in a
tonsillar carcinoma . -
pubmed
One cervical
carcinoma harbored
HPV 11 DNA . -
pubmed
Using
HPVs 6 , 11 , 16 , 18 and 33 anticontamination primers and probes in PCR , no additional high - risk HPV types could be detected in these four
cancers . -
pubmed
CONCLUSION : This report shows the presence of low - risk
HPVs (
HPV 6 and 11 ) associated to malignant
tumors in a frequency higher than usually observed . -
pubmed
The data raise questions about which are the circumstances which may favor low - risk
HPV related
oncogenesis . -
pubmed
OBJECTIVE : The Agency for Health Care Policy and Research ( AHCPR ) has recently published guidelines for the management of
patients with
acute low back pain , which include recommendations for the use of lumbar radiographs , based on the identification of " red flags " for
fractures ,
tumors , or
infections . -
pubmed
PATIENTS : The records of all patients seen in 1992 and 1993 with a new episode of
low back pain were reviewed : 963
patients had a history of
back pain of less than 3 months . -
pubmed
RATIONALE AND OBJECTIVES : We determined whether a limited number of high - resolution computed tomography ( HRCT ) scans will effectively screen for
interstitial lung disease (
ILD ) in a population of
individuals exposed to asbestos . -
pubmed
PURPOSE : We present our experience with preoperatively administered
hyperbaric oxygen therapy to
patients who have sustained significant therapeutic radiation induced
soft tissue injuries and subsequently undergo planned abdominal intervention / surgery . -
pubmed
Internal radiation therapy for
patients with primary or metastatic
hepatic cancer : a review . -
pubmed
BACKGROUND : The limited efficacy of current approaches to the treatment of
patients with
hepatic cancer , including external beam radiation therapy and cytotoxic chemotherapy , has reawakened interest in the use of internal radiation therapy . -
pubmed
METHODS : The authors reviewed series of
patients with liver
metastases or
hepatocellular carcinoma (
HCC ) treated with 1 ) interstitial irradiation and direct intratumoral injection of 90Y microspheres , 2 ) intraarterial infusion of
( 131 ) I - Lipiodol , 3 ) intraarterial infusion of 90Y microspheres , or 4 ) parenteral administration of radiolabeled monoclonal antibodies . -
pubmed
RESULTS : High dose rate interstitial irradiation with afterloading of
( 192 ) Ir resulted in local control of
hepatic metastases for a median of 8 months and complete
tumor eradication in 2
patients . -
pubmed
Direct intratumoral injection of 90Y microspheres reduced the size of 90.6 % of
tumors and completely destroyed them in 8
patients . -
pubmed
Partial response was commonly achieved when
patients with unresectable
liver metastases or
HCC were treated with intraarterial
9OY microspheres . -
pubmed
Among four
patients whose
HCC became resectable following treatment with 90Y microspheres , two cases of complete remission were documented . -
pubmed
and
Anopheles funestus rank among the world 's most efficient vectors of
human malaria . -
pubmed
DESIGN : Case report of a 64 - year - old
man who developed
weakness and
numbness of the distal legs after an operation for
mesenteric thrombosis . -
pubmed
[ T lymphocyte immunological response to different antigenic fractions of
Mycobacterium bovis in
juvenile chronic polyarthritis ] . -
pubmed
RESULTS :
Patients with
juvenile chronic polyarthritis had a intense reaction against 65 kDa fraction and a second fraction located between 32.5 and 27.5 kDa . -
pubmed
Sperm retrieval and intracytoplasmic sperm injection in
patients with
prune - belly syndrome . -
pubmed
In
humans , IGF-1 improves cardiac function after
myocardial infarction by stimulating contractility and promoting tissue remodeling . -
pubmed
Treatment of
patients with
Paget ' s disease of bone . -
pubmed
OBJECTIVE : The role of surgery in the treatment of
patients with pulmonary and hepatic
metastases from
colorectal cancer has not been delineated . -
pubmed
METHODS : Of the 351
patients enrolled in the
Metastatic Lung Tumor Study Group of Japan between June 1988 and June 1996 who underwent thoracotomy for pulmonary
metastases from
colorectal cancer , 47 also underwent hepatic resection for metastatic
tumors . -
pubmed
This
patient was alive without
recurrence . -
pubmed
There was a significant difference in the cumulative survival of the
patients with a solitary pulmonary
metastasis and the
patients with multiple pulmonary
metastases ( P = .04 ) . -
pubmed
However , 9 of 10
patients who survived 3 years or more after the initial thoracotomy had only one or two
hepatic metastases . -
pubmed
Patients with a solitary pulmonary
metastasis and a small number of
hepatic metastases are good candidates for resection . -
pubmed
In a genome - wide screening of the MRL background genes mediating susceptibility to
collagen diseases using N2 progeny
mice MRL / lpr x ( MRL / lpr x C3H / lpr ) F1 , we previously found that each
collagen disease is controlled by a different set of genes . -
pubmed
From their composition these loci seemed to be derived from AKR / J ( for one ) and LG / J ( for another two )
strains , and appeared to act in an additive manner on the development of
vasculitis , indicating that
vasculitis in MRL / lpr
mice is inherited in a polygenic manner . -
pubmed
Two
patients had a non - Q
myocardial infarction . -
pubmed
Prion diseases have aroused particular interest ever since the appearance of
BSE (
mad cow disease ) , a
prion disease of
cattle that can apparently be transmitted to
humans and which is the cause of a new variant of
Creutzfeldt - Jakob disease . -
pubmed
Fertilization , development , and chromosomal status of the embryos were compared with a control group ( n = 18 ) of
patients undergoing preimplantation genetic diagnosis for
sex chromosome - linked diseases . -
pubmed
OBJECTIVE : To assess the potential for the development of
aluminum toxicity in
patients with
renal insufficiency or
chronic renal failure who are taking
sucralfate . -
pubmed
Accumulation of
aluminum in
patients with
impaired renal function may lead to significant
toxicity . -
pubmed
Studies and case reports evaluating the use and
toxicity of
sucralfate in
patients with normal renal function , as well as those with
renal failure or
renal insufficiency , were reviewed . -
pubmed
CONCLUSIONS :
Aluminum accumulation and
toxicity have been reported with the use of
sucralfate in
patients with
compromised renal function . -
pubmed
The risk of
toxicity most likely represents a long - term complication of
sucralfate use in this
patient population . -
pubmed
These medications , in addition to
sucralfate , should be avoided if possible in
patients with
end - stage renal disease . -
pubmed
Patients with
renal failure or
renal insufficiency who are undergoing prolonged
sucralfate therapy should be monitored for potential signs of
aluminum toxicity . -
pubmed
[ Intravenous and enteral nutrition for the
patient with
cerebrovascular disease ] . -
pubmed
The
Syrian golden hamster strain LPN : a useful
animal model for
human cholelithiasis . -
pubmed
The purpose of this study was to specify the main mechanisms at the origin of
gallstone formation in very young ( 5 - week old ) or young adult ( 9 - week old ) LPN
hamsters fed a
sucrose - rich ( normal lipid ) lithogenic diet for one and four weeks , respectively . -
pubmed
It was also to compare these mechanisms in the two
strains of
hamsters ( LPN and Janvier ) or when an anti - lithiasic diet was given by substituting 10 % of the
sucrose by beta cyclodextrin . -
pubmed
The LPN
strain of
hamsters showed a very high incidence of
cholesterol gallstones ( 73 % ) after receiving the lithogenic diet . -
pubmed
The
gallstone formation is very rapid and occurs in less than one week in very young
hamsters which show a high
cholesterol synthesis rate in the liver . -
pubmed
An overall comparison of the data obtained in LPN
Hamsters and in
Man suggests that this
hamster strain appears to be an interesting model for
human cholelithiasis . -
pubmed
[
Secondary biliary cirrhosis in a
patient with
histiocytosis X ] . -
pubmed
The authors present the clinical case of a 62 - year - old female
patient , hospitalized for
chronic cholestasis ,
diabetes and
gallstone in the main bile duct . -
pubmed
Genetic targeting and/or pharmacologic blockade of the implicated pathways may be a future strategy for therapeutic adjunctive measures to improve outcome and may hold substantial promise , in concert with antimicrobial agents , in
humans with acute
bacterial meningitis . -
pubmed
In this study , 39
patients with
PD and 25 control subjects without
neurologic disease completed testing in a driving simulator . -
pubmed
PD patients had more total collisions on the driving simulator than control subjects ( t = -3.7 , p < 0.01 ) . -
pubmed
RESULTS : Among children ,
hepatitis A virus was the major etiologic agent ( 81.6 % in Group A and 51.4 % in Group B ) , followed by
hepatitis E virus ( 12.2 % , 46.4 % ) and
hepatitis B virus ( 5.4 % , none ) . -
pubmed
Among adults ,
hepatitis E virus was the main causative agent ( 42.4 % in Group A and 71.2 % in Group B ) followed by
HBV ( 28 % , 25.5 % ) and
hepatitis A virus ( 10.6 % , 3.5 % ) . -
pubmed
Cryptosporidium parvum , a protozoan parasite , has been implicated in a number of
waterborne disease outbreaks and is difficult to inactivate using free
chlorine . -
pubmed
The type
strain is strain
29W ( T ) (= JCM 11663(T ) = DSM 15103(T ) ) . -
pubmed
[ Effect of
catechol amines on
oxygen consumption in
hypercapnia in
dogs ] . -
pubmed
Mood induction with facial expressions of emotion in
patients with
generalized anxiety disorder . -
pubmed
Patients with
general anxiety disorder (
GAD ) ,
anxiety prone subjects , and normal controls ( n=30 , N=90 ) were subjected to happy and sad mood induction conditions using facial expressions of emotion of varied intensity . -
pubmed
A phase I and pharmacokinetic study of
irinotecan in
patients with
hepatic or renal dysfunction or with prior pelvic radiation : CALGB 9863 . -
pubmed
BACKGROUND : To ascertain if
hepatic or renal dysfunction or prior pelvic radiation ( XRT ) leads to increased
toxicity at a given dose of
irinotecan and to characterize the pharmacokinetics of
irinotecan and its major metabolites in
patients with
hepatic or renal dysfunction . -
pubmed
PATIENTS AND METHODS :
Adults with
tumors appropriate for
irinotecan therapy and who had
abnormal liver or renal function tests or had prior radiation to the pelvis were eligible . -
pubmed
RESULTS : Thirty - five
patients were evaluable for
toxicity . -
pubmed
No dose - limiting
toxicity was seen in cohort I , although only three
patients were treated and at a dose of 225 mg / m(2 ) . -
pubmed
Patients with elevations of direct
bilirubin had dose - limiting
toxicities , even though the starting dose was 145 mg / m(2 ) . -
pubmed
Patients with elevations of
creatinine or with prior pelvic radiotherapy did not appear to have increased risk of
toxicity at the doses explored in this study . -
pubmed
CONCLUSIONS :
Patients with elevated
bilirubin treated with
irinotecan have an increased risk of
toxicity and a dose reduction is recommended . -
pubmed
Herbal preparations derived from
black walnut have been used as hair dyes and skin colorants in addition to being applied topically for the treatment of
acne ,
inflammatory diseases ,
ringworm , and fungal ,
bacterial , or
viral infections . -
pubmed
METHODS : Twenty
patients with
verrucous epidermal nevi were treated with Er : YAG laser . -
pubmed
RESULTS : After a single laser treatment , successful elimination of the
verrucous epidermal nevi was observed in 15
patients . -
pubmed
Five
patients ( 25 % ) showed a
relapse within 1 year after the treatment . -
pubmed
Erythema occurred in all
patients after the laser treatment and subsided in 2 months . -
pubmed
Postinflammatory
hyperpigmentation occurred in two
patients ( 10 % ) . -
pubmed
One
patient ( 5 % ) experienced transient
hypopigmentation . -
pubmed
Mild to moderate postoperative
acne flare - up occurred in one
patient ( 5 % ) with
facial lesions . -
pubmed
INTRODUCTION : In a follow - up examination 50
patients who had sustained
dorsal dislocations of the proximal interphalangeal ( PIP ) joint , the results of two conservative therapy regimens , either immobilisation or early motion , were investigated . -
pubmed
The inclusion criteria were : adult
patients over the age of 18 with isolated , acute , closed dorsolateral
dislocation of the PIP joint . -
pubmed
Two
patients complained of a limitation of extension , 3 of limitation of extension and
pain , and 1 of
pain and
swelling . -
pubmed
Palmar instability did not occur , and 18
patients were satisfied . -
pubmed
One
patient complained of instability ,
pain and lack of extension during hard work , 1 of
pain in combination with instability , 2 of
pain and 3 of
swelling of the joint . -
pubmed
Proof of the mysterious efficacy of
ginseng : basic and clinical trials : effects of
red ginseng on
learning and memory deficits in an
animal model of
amnesia . -
pubmed
Ameliorating effects of
red ginseng on
learning and memory deficits due to
hippocampal lesions and aging were reviewed ; the performance of young
rats with selective
hippocampal lesions with or without
red ginseng ( p.o . ) -
pubmed
The results in the
DMT and RRPST indicated that motivational and motor activity of young
rats with
hippocampal lesions with and without ginseng and aged
rats with and without
ginseng were not significantly different from that of control young
rats . -
pubmed
However , young
rats with
hippocampal lesions without ginseng and aged
rats without
ginseng displayed significant deficits in the PLT . -
pubmed
Treatment with
red ginseng significantly ameliorated place - navigation deficits in young
rats with
hippocampal lesions in the PLT . -
pubmed
The results , along with previous studies showing significant effects of
red ginseng on the central nervous system , suggest that
red ginseng ameliorates
learning and memory deficits through effects on the central nervous system , partly through effects on the hippocampal formation . -
pubmed
These improved immunophenotypic definitions of
macaque NK cells should facilitate future analysis of innate immune responses in
rhesus macaques and the role of NK cells in
AIDS pathogenesis in
Simian immunodeficiency virus ( SIV )- infected macaques . -
pubmed
Importantly though , the product appears to be relatively free of antigenicity ,
thrombogenicity and risk of
viral transmission that , in the past , have limited the utility of blood products . -
pubmed
METHODS : We analyzed data for all pregnant
women admitted to the hospital in Canada over 7 years to test whether major
trauma still clustered in the summer despite their aversion toward
alcohol , recklessness , and extreme sports . -
pubmed
The 133
women included were divided into two groups : ( 1 )
Non - brachial plexus injury ( Non - BPI ) group : 106 women with labours complicated by
shoulder dystocia . -
pubmed
BACKGROUND : Little is known about the neuropsychological status of
youth with
bipolar disorder (
BPD ) or whether
cognitive deficits in this population are accounted for by comorbidity with
attention deficit / hyperactivity disorder (
ADHD ) . -
pubmed
We compared neuropsychological and academic functioning of
youth with and without
DSM - IV BPD , controlling for effects of comorbid
ADHD . -
pubmed
METHODS : Fifty - seven
youth with
BPD and 46 healthy control subjects were assessed on a battery of clinical neuropsychological measures including subtests from the Wechsler Intelligence Scales for Children and Adults ( Third Editions ) , the Stroop , the Wisconsin Card Sorting Test , the Rey - Osterreith Complex Figure , an auditory working memory Continuous Performance Test , a measure of verbal learning , and the Wide Range Achievement Test - Third Edition . -
pubmed
This metaregression analysis examines the relationship between several surrogate markers and survival in
women with advanced
breast cancer after receiving first - line combination
anthracycline chemotherapy
5 - fluorouracil ,
adriamycin and
cyclophosphamide (
FAC ) or
5 - fluorouracil ,
epirubicin and
cyclophosphamide (
FEC ) . -
pubmed
PURPOSE : To validate the accuracy of ventricular function analysis using a single breath - hold real - time steady sate free precession ( SSFP ) cine MR method and demonstrate its application during
adenosine stress imaging in
children with
congenital heart disease . -
pubmed
CONCLUSION : Single breath - hold real - time SSFP cine imaging is robust and accurate in assessing cardiac function in
children with
congenital heart disease . -
pubmed
Two other clusters , joined at a similarity of 53 % , included reference
strains of
Bradyrhizobium elkanii , but not
USDA 76 T ; furthermore , two other major clusters were identified and all
strains were clustered at a final level of similarity of only 28 % . -
pubmed
Reference
strains of
B. - pubmed
japonicum fell into a major group with 51
strains , 84 % isolated from
soybean , with a similarity of 59 % , while
strains of
B. - pubmed
In a combined analysis with the three ribosomal regions , the majority of
strains isolated from
soybean clustered with a similarity of 54 % with type and reference
strains of
B. - pubmed
japonicum , while most
strains isolated from Brazilian indigenous legume species grouped with
B. - pubmed
OBJECTIVE : Activated synoviocytes play important roles in the progression of
human osteoarthritis (
OA ) . -
pubmed
METHOD : Synovial fluid - derived FLS were obtained from the knees of 15
patients with early stage
OA . -
pubmed
METHODS : In this study , both - ends - threaded locking screws were used to treat 68
tibial fractures , including 56 acute
fractures in 54
patients and 12 nonunions in 12
patients . -
pubmed
Three
patients underwent exchange nailing and bone grafting and had eventual
fracture union . -
pubmed
Recovery of joint motion was essentially normal in
patients without
knee or ankle injury . -
pubmed
Three
patients died of their
disease ( 17.6 % ) , 2
patients died from unrelated reasons , 1 patient was lost to follow - up , and the other 12
patients are alive with no evidence of disease . -
pubmed
CASE REPORT : We report on a
woman patient in whom
craniocerebral trauma involved a
fracture of the left optic canal with unilateral
loss of vision . -
pubmed
RESULTS : Occult
DCM was diagnosed in 21
dogs . -
pubmed
Additional studies should be performed to optimize this method of screening
dogs to detect occult
DCM . -
pubmed
Differential impact of heavy cannabis use on sensory gating in
schizophrenic patients and otherwise healthy controls . -
pubmed
cannabis controls ; n=11 ) and compared it to that of
schizophrenic patients ( n=12 ) and healthy controls ( n=18 ) without cannabis or other
drug abuse . -
pubmed
RESULTS : A total of 561
polyps in 486
patients were resected by endoscopic polypectomy . -
pubmed
Overall ,
bleeding complications occurred in 7.6 % ( 37/486 ) of the
patients , including 4.9 % ( 12/244 ) in the
epinephrine group , and 10.3 % ( 25/242 ) in the saline group . -
pubmed
Early and late postpolypectomy
bleeding (
PPB ) occurred in 6.6 % ( 32/486 ) and 1 % ( 5/486 ) of the
patients , respectively , including 4.5 % ( 11/244 ) , 0.4 % ( 1/244 ) in the
epinephrine group , and 8.7 % ( 21/242 ) , 1.7 % ( 4/242 ) in the saline group . -
pubmed
Spatial patterns of
brain atrophy in
MCI patients , identified via high - dimensional pattern classification , predict subsequent
cognitive decline . -
pubmed
Approximately 2/3 of the
MCI group presented patterns of
atrophy that overlapped with
AD , whereas the remaining 1/3 overlapped with cognitively normal
individuals , thereby indicating that some , but not all ,
MCI patients have significant and extensive
brain atrophy in this cohort of
MCI patients . -
pubmed
Rats were implanted with
9L gliosarcomas and the
tumors were diagnosed by MRI . -
pubmed
Muscle tenderness is an important complex trait for meat quality and thus for genetic improvement through
animal breeding . -
pubmed
Muscle ( longissimus dorsi ) samples from 30 F(2 )
pigs were characterized by Warner - Bratzler Shear Force ( WBSF ) on cooked meat as a measurement of
muscle tenderness . -
pubmed
It has been shown that elderly
patients with
dementia treated with atypical and conventional antipsychotics have a twofold increased risk of cerebrovascular adverse events ( CVAEs ) . -
pubmed
The risk of
CVAE in elderly
patients associated with antipsychotics is elevated especially during the first weeks of treatment . -
pubmed
Large variability of
aripiprazole and
dehydroaripiprazole serum concentrations in adolescent
patients with
schizophrenia . -
pubmed
In 33 consecutively admitted
patients of a
child and adolescent
psychiatric hospital [ age ( mean + /- standard deviation ) 18.7 + /- 1.7 years ( range , 13.5 - 21.6 years ) ] , 117 steady - state serum concentrations ( repeated samples from
individuals ) of
aripiprazole and its metabolite
dehydroaripiprazole were assessed using high - performance liquid chromatography . -
pubmed
Resveratrol , present in
grapes and red wine , is reported to be a natural chemopreventive agent against
cancer . -
pubmed
Recent advances in our understanding of basic biological processes have resulted in the opening of new avenues for treatment of
human genetic diseases , especially single gene disorders . -
pubmed
A significant proportion of
human genetic disorders have been shown to be caused due to degradation of transcripts for specific genes through a process called nonsense mediated decay ( NMD ) . -
pubmed
METHOD : All
patients referred for the treatment of
haemorrhoids over a period of 5 years were prospectively included in a database . -
pubmed
In contrast ,
TB control remains poor in many developing countries , especially those worst affected by poverty and the
human immunodeficiency virus (
HIV ) epidemic . -
pubmed
Novel real - time PCR assay for simultaneous detection and differentiation of
Clostridium chauvoei and
Clostridium septicum in clostridial
myonecrosis . -
pubmed
In this study we used FreeSurfer , a freely - available and automated software tool , to measure cortical thickness in 28 pathologically - confirmed
AD patients , of which 11 had a typical amnestic presentation and 17 an atypical presentation during life , 23 pathologically - confirmed
FTLD subjects , and 25 healthy controls . -
pubmed
In contrast , lower cortical thickness in the anterior temporal lobe and frontal lobe is indicative of the presence of
FTLD pathology in
patients with a clinical presentation of
FTD . -
pubmed
Reduced cortical thickness in the posterior cingulate gyrus is characteristic of
AD pathology in
patients with typical and atypical clinical presentations of
AD , and may assist a clinical distinction of
AD pathology from
FTLD pathology . -
pubmed
Therefore , we hypothesized that
PD patients would have difficulty switching from one saccade response to the other , with particular impairment in switching from a pro to an antisaccade . -
pubmed
Effects of combination
dobutamine and
vasopressin therapy on microcirculatory blood flow in a
porcine model of severe
endotoxic shock . -
pubmed
In a phase III trial ( the UK ABC-02 trial ) conducted by the American Society of Clinical Oncology ( ASCO ) in 2009 , in which
gemcitabine +
CDDP combination therapy was compared against
gemcitabine monotherapy to treat
patients with advanced or metastatic
biliary tract cancers , the overall duration of survival was significantly prolonged and the mortality risk reduced . -
pubmed
We retrospectively reviewed the medical records of 28
patients with
oropharyngeal cancer , who were treated with immediate reconstruction with an
ALT free flap after excision . -
pubmed
Most of the
patients had T3 - 4
tumours and involved neck nodes . -
pubmed
coli (
UPEC ) from countries with high
infection burden , such as India , hinders the
infection control and management efforts . -
pubmed
coli isolates from India as well as 50
ExPEC strains from Germany . -
pubmed
Our aim was to combine the use of the hen
animal model and microarray technology to identify differentially expressed genes in ovarian tissue from
normal hens compared with hens with
ovarian cancer . -
pubmed
We found that the transcripts up - regulated in
chicken ovarian
tumors were enriched for oviduct - related genes . -
pubmed
In addition , one of the oviduct - related genes identified in our analysis , paired box 2 has been implicated in
human ovarian cancer and may serve as a marker of the disease . -
pubmed
The expression of oviduct - related genes in early - stage
tumors is similar to what is seen in
human ovarian cancer , with
tumors resembling
normal Mullerian epithelium . -
pubmed
These data suggest that
chicken ovarian tumors may arise from alternative sites , including the oviduct . -
pubmed
The mean age was 6.9 months ( SD 5.7 ) ; the mean number of days between skeletal surveys was 18.7 ( SD 10.1)Four
children ( 8.5 % ) had signs of healing
bone trauma on a follow - up skeletal survey . -
pubmed
A series of
beta - carboline derivatives bearing a substituted -
carbohydrazide moiety at C-3 were synthesized and evaluated for their antitumor activity against eight
human cancer cell lines . -
pubmed
Rituximab induces resolution of recurrent diffuse
alveolar hemorrhage in a
patient with primary
antiphospholipid antibody syndrome . -
pubmed
We describe a
patient with primary
APS and refractory recurrent episodes of
DAH . -
pubmed
The
patient was admitted 15 times due to recurrent episodes of
DAH in a period of 18 months . -
pubmed
In a follow - up of more than 2 years after he received rituximab , the
patient has had no further admissions due to
DAH . -
pubmed
We assessed the use of FRET - based substrates in an assay to distinguish
breast cancer patients from controls . -
pubmed
Oseltamivir is recommended by the World Health Organization ( WHO ) for use in the clinical management of
pandemic and seasonal influenza of varying severity , and as the primary antiviral agent for treatment of
avian H5N1 influenza infection in
humans . -
pubmed
The analysis of possible morphogenesis of the different structures in
human yolk sac
tumor has been considered . -
pubmed
Transcatheter closure of a residual
patent ductus arteriosus after surgical ligation in
children . -
pubmed
SUBJECTS AND METHODS : Between June 2005 and December 2009 , transcatheter occlusion of residual
postsurgical ductus arteriosus was performed in six
children . -
pubmed
We retrospectively reviewed the electroencephalography laboratory database and paediatric neurology clinic records ( from January 2000 to June 2009 ) at our institution in order to identify
patients with
absence seizures beginning before age three . -
pubmed
Seven of 12
patients had normal neurodevelopment and five had
speech delay . -
pubmed
Four
patients were
seizure - free without AEDs , three were
seizure - free with a single AED , and five still had
seizures with multiple AEDs . -
pubmed
Three
patients had
recurrences after medication withdrawal . -
pubmed
Other previously published series have identified better
seizure control than that reported here , however , 16 % of the 130
patients so far documented are reported to have poorly controlled
epilepsy , indicating that early - onset
CAE is not a homogeneous condition . -
pubmed
Emerging evidence on rehabilitative interventions and advancements in concomitant surgeries , including those addressing
chondral and meniscal injuries , continues to grow and greatly affect the rehabilitative care of
patients with anterior cruciate ligament reconstruction . -
pubmed
Death occurred in 28
patients over a median follow - up of 3.2 years . -
pubmed
METHODS :
Children aged 6 to 13 years old who received a diagnosis of
PS in our previous community - based
OSA prevalence study were invited to undergo repeat polysomnography ( PSG ) at 4 - year follow - up . -
pubmed
CONCLUSIONS : More than one - third of school - aged
children with
PS progressed to
OSA over a 4 - year period , although only 7.1 % developed moderate to severe disease . -
pubmed
RESULTS : A total of 25
children and 15 adults with
spina bifida were studied . -
pubmed
Cone survival and preservation of visual acuity in an
animal model of
retinal degeneration . -
pubmed
To this purpose , we compared rod and cone viabilities by both ex vivo and in vivo determinations in the rd10 mutant
mouse , a validated model of
human retinitis pigmentosa . -
pubmed
The results of biochemical , morphological and functional assays converged to show that , in treated rd10
mice cone photoreceptors , the inner retina and overall visual performance were preserved well after rod
death . -
pubmed
Effects of
cabergoline on
hyperprolactinemia , psychopathology , and sexual functioning in schizophrenic
patients . -
pubmed
Our data suggest that
cabergoline administration to clinically stable
patients with
schizophrenia may improve sexual functioning without adversely affecting their psychopathologic status , provided that the dose has been suited to the severity of the
hyperprolactinemia . -
pubmed
BACKGROUND :
Depression is the most common psychiatric manifestation in
patients with
Parkinson ' s disease (
PD ) . -
pubmed
The prevalence of recurrent
headache was 30.1 % ( 620/2057 ) ,
girls 35.1 % , boys 25.2 % . -
pubmed
The emergence of multidrug - resistant
strains of
Neisseria gonorrhoeae constitutes a serious threat to public health and necessitates the discovery of new types of antimicrobial agents . -
pubmed
We describe three clinical cases of
adolescents presenting to an
eating disorders program with primary complaints of gastrointestinal symptoms , food avoidance , and associated
weight loss . -
pubmed
METHODS :
Patients who underwent laparoscopic umbilical
hernia repair were separated by method of mesh fixation : sutures versus primarily tacks . -
pubmed
Additionally , a telephone interview was conducted to assess
postoperative pain , recovery time , and overall
patient satisfaction . -
pubmed
Hernia recurrence occurred in 3 and 2
patients in the sutures and tacks groups , respectively ( P was not significant ) . -
pubmed
Diabetes patients are at high risk for development of
cardiovascular disease . -
pubmed
From current data ,
alogliptin and
saxagliptin do not change cardiovascular risk in
type 2 diabetes mellitus (
T2DM )
patients . -
pubmed
Vildagliptin does not alter myocardial function in
T2DM patients with
systolic dysfunction . -
pubmed
However , the possibility of an increase in clinical
heart failure and worsened outcomes in
patients with existing
heart failure is suggested by current data . -
pubmed
RESULTS : Repetitive challenge divided the
monkeys into two groups with respect to their susceptibility to
infection : highly susceptible ( 2 - 3 challenges , 5
monkeys ) and poorly susceptible ( & gt;=6 challenges , 3
monkeys ) . -
pubmed
Differences in persistency with
teriparatide in
patients with
osteoporosis according to gender and health care provider . -
pubmed
UNLABELLED : This analysis investigated the persistence of
teriparatide for treatment of
osteoporosis in 829
patients according to gender and health care provider treated with
teriparatide . -
pubmed
We found a highly significant decreased risk for treatment discontinuation in
patients with
fractures prior to treatment initiation compared to those without such
fractures ( hazard ratio ( HR ) 0.77 ; 95 % confidence interval ( CI ) 0.66 - 0.90 ) . -
pubmed
TPTD persistence in
patients with
osteoporosis is higher than with antiresorptives but is still suboptimal and needs to be improved to ensure
fracture risk reductions comparable to randomized controlled trial ( RCT ) results . -
pubmed
The aim of the work is to discuss on isolated single coronary artery in two
adults presenting as
acute coronary syndrome . -
pubmed
Having been prescribed Mu Tong that was adulterated with Guan Mu Tong (
Aristolochia manshuriensis ) before 2004 , or an estimated consumption of more than 1 - 100 mg of
aristolochic acid , were both associated with an increased risk of
UC in the multivariable analyses . -
pubmed
METHODS AND RESULTS : We studied a total of 74
human coronary plaque specimens obtained at autopsy . -
pubmed
Evaluation of safety and efficacy of intravenous
zanamivir in the treatment of hospitalized Japanese
patients with
influenza : an open - label , single - arm study . -
pubmed
There is an unmet need for a parenteral
influenza antiviral therapy to treat hospitalized
patients . -
pubmed
Therefore the safety and efficacy profile of intravenous
zanamivir (
IVZ ) was examined in Japanese
patients with severe
influenza . -
pubmed
Patients hospitalized with
influenza were treated with
IVZ 600 mg twice daily for five days . -
pubmed
CONCLUSIONS : In this study there were no new significant safety findings or patterns of AEs related to
IVZ and therefore the safety profile was confirmed for a small sample of Japanese hospitalized
patients with
influenza . -
pubmed
This strategy may lead to significant
tumor regression , ultimately leading to a complete pathologic response in up to 42 % of
patients . -
pubmed
INTRODUCTION :
Dermoids of the Eustachian tube are rare benign
developmental tumours that typically occur in female
children . -
pubmed
This approach could be used also in new - born
children , decreasing the morbidity of the classic surgical treatment and avoiding the risk of
craniofacial alterations . -
pubmed
HIV /
AIDS and family planning services integration : review of prospects for a comprehensive approach in sub - Saharan Africa . -
pubmed
However , the integration of family planning into HIV /
AIDS programmes , or vice versa , would permit women of reproductive age who are infected or affected by HIV to benefit from family planning and/or
HIV - prevention counselling and services . -
pubmed
Is Immediate Radical Cystectomy Necessary for All
Patients with Non - Muscle - Invasive Micropapillary
Bladder Cancer ? -
pubmed
The hypothesis is that non - muscle - invasive (
NMI )
MPUC may have a heterogeneous prognosis , and detailed pathological analysis may identify
patients that could be managed without immediate cystectomy . -
pubmed
PATIENTS AND METHODS : This is a retrospective analysis of
patients presenting with
MPUC in a primary transurethral resection specimen ( n = 40 ) . -
pubmed
[ Successful Hematopoietic Cell Transplantation Following
Azacitidine Treatment in an
Acute Myeloid Leukemia Patient with t(3;3)(q21;q26.2 ) Translocation and Marked
Thrombocythemia ] . -
pubmed
A 39 - year - old
man visited our department complaining of general
malaise and
appetite loss . -
pubmed
Since the
patient 's disease had progressed to
acute myeloid leukemia (
AML ) with an increase in the peripheral blast count , he was diagnosed with
AML along with t(3;3 ) ( q21;q26.2 ) through a bone marrow aspiration sample . -
pubmed
Moreover , recent advancements in our ability to diagnose
cMPN have paralleled the development of large clinical trials for
patients with
cMPN . -
pubmed
This article provides explanatory information from these large clinical trials that is useful for the actual clinical practice of caring for
patients with
cMPN in Japan . -
pubmed
METHODS AND RESULTS : We report a
cavernous hemangioma extruding from the internal auditory canal , diagnosed after a left translabyrinthine resection in a 45 - year - old
man complaining of profound
sensorineural hearing loss , with no facial
paresis or
dizziness . -
pubmed
PURPOSE : The choice of distal fusion level in adolescent
idiopathic scoliosis (
AIS )
patients with major thoracolumbar or lumbar ( TL / L ) curves ( Lenke type 3C , 5C , or 6C ) remains debatable . -
pubmed
Persistent
infection by
Staphylococcus epidermidis in endodontic flare - up : a case report . -
pubmed
A 47 - year - old
man reported
pain on percussion after uncomplicated retreatment of the maxillary left canine for prosthetic purposes . -
pubmed
Five castrated
lambs with initial
body weights of 36.8 + -3.3 kg , distributed in a Latin square ( 5x5 ) design , were used . -
pubmed
CONCLUSIONS : Advances in diagnostic and therapeutic techniques , including surgical cytoreductive techniques , have demonstrated significant survival gains in
patients with
peritoneal disease . -
pubmed
Role of the Common Fragile Sites in
Cancers with a
Human Papillomavirus Etiology . -
pubmed
High - risk
human papillomaviruses (
HPVs ) are known to be associated with different
anogenital cancers including cervical , anal , penile , and
vaginal cancers . -
pubmed
The model for how high - risk
HPVs induce
cancer formation comes from studies of
cervical cancer which usually involves integration of the
HPV into the
human genome and subsequent changes due to induced
chromosomal instability . -
pubmed
In addition , we summarize studies now done in
OPSCC which demonstrate that the role of
HPV in these
cancers may be different from that in
cervical cancer . -
pubmed
Finally , we propose new models for how
HPV may be involved in the formation of these 2
cancers . -
pubmed
Older
people aged equal or over 60 without any
psychiatric diagnosis were enrolled as healthy controls . -
pubmed
OBJECTIVE : To evaluate the feasibility and outcomes of
patients operated on for uncomplicated
acute appendicitis (
UAA ) in our 24 - h emergency outpatient surgery unit . -
pubmed
The median length of hospital stay was 13 h.
Postoperative complications were observed in six
patients ( 6 % ) . -
pubmed
For about 30 years , soon after the onset of the
AIDS epidemic , sexual - health messaging has emphasized personal responsibility for using condoms to protect from acquiring or transmitting
HIV or other
sexually transmitted infections . -
pubmed
RESULTS : In the training cohort , median follow - up was 3.0 years ( range , 0.43 - 6.56 years ) and
relapse occurred in 36 % of
patients . -
pubmed
RESULTS AND CONCLUSIONS : In both
human and animal studies ,
neuropathic pain has been associated with a pro - inflammatory state . -
pubmed
Forty - five
patients ( 2.2 % ) had a
postoperative complication , and 74 ( 3.7 % ) patients were readmitted to the hospital after discharge . -
pubmed
Lung clearance index ( LCI ) is a marker of ventilation inhomogeneity that is raised in some but not all
patients with
PCD . -
pubmed
We hypothesised that
PCD patients with
microtubular defects would have worse ( higher ) LCI than other
PCD patients . -
pubmed
METHODS : Spirometry and LCI were measured in 69 stable
patients with
PCD . -
pubmed
RESULTS : Of the 135
patients who underwent surgery for
IPMN , 50 ( 37.0 % ) had
low / intermediate - grade dysplasia , 25 ( 18.5 % ) had
high - grade dysplasia , and the remaining 60 ( 44.5 % ) had invasive
carcinoma . -
pubmed
We present a clinical case of a 47 - year - old asymptomatic
woman with symptomatic
bladder leiomyoma . -
pubmed
BACKGROUND :
Hyperlactataemia (
HL ) is a biomarker of disease severity that predicts mortality in
patients with
sepsis and
malaria . -
pubmed
RESULTS : Of 3170 children in the FEAST trial , including 1719
children ( 57 % ) with
Plasmodium falciparum malaria , 3008 ( 95 % ) had a baseline
lactate measurement , 2127 ( 71 % ) had
HL (
lactate & gt;= 2.5 mmol / L ) , and 1179 ( 39 % ) had severe
HL ( & gt;= 5 mmol / L ) . -
pubmed
SELECTION CRITERIA : We included published or unpublished randomised controlled trials ( RCTs ) that enrolled
adults with
venous leg ulcers and compared the effects of at least one of the following interventions with any other intervention in the treatment of
venous leg ulcers : any dressing , or any topical agent applied directly to an open
venous leg ulcer and left in situ . -
pubmed
Clinical characteristics and type of antithrombotic treatment in a Spanish cohort of elderly
patients with
atrial fibrillation according to dependency ,
frailty and
cognitive impairment . -
pubmed
Background : Available data regarding clinical profile and management of elderly
patients with
atrial fibrillation (
AF ) according to dependency , fragility and
cognitive impairment are scarce . -
pubmed
The objective of the study was to analyze the biodemographic data , clinical profile and antithrombotic treatment according to dependency , fragility and
cognitive impairment in elderly
AF patients . -
pubmed
Methods : Cross - sectional and multi - center study performed in consecutive
AF patients & gt;= 75 years treated with oral anticoagulants & gt;= 3 months attended in Internal Medicine Departments in Spain . -
pubmed
This distribution was independent of the presence of dependency or fragility , but there was a trend to a higher prescription of
vitamin K antagonists in those
patients with
cognitive impairment ( 75.2 % vs. 68.8 % ; P = 0.05 ) . -
pubmed
Conclusions : Approximately 32%-44 % of elderly anticoagulated
AF patients attended have some degree of dependency , fragility and/or
cognitive impairment . -
pubmed
Approximately 71 % of
patients are taking
vitamin K antagonists , regardless dependency or
frailty , but with a trend to higher prescription in
patients with
cognitive impairment . -
pubmed
Surgical resection represents the standard therapy for
patients with
colorectal liver metastases (
CRLM ) . -
pubmed
Legiolert is a new culture method for quantification of
Legionella pneumophila , which is the primary species associated with
Legionnaires ' disease . -
pubmed
Nail dermoscopy ( onychoscopy ) is useful in diagnosis and treatment follow - up of the
nail mixed infection caused by
Pseudomonas aeruginosa and
Candida albicans . -
pubmed
Combined
carbon dioxide laser and cryosurgical ablation of
rostral nasal septum squamous cell carcinoma in 10
dogs . -
pubmed
OBJECTIVES : The study aim was to evaluate the efficacy of combination
carbon dioxide (
CO2 ) laser surgery and cryosurgery as a palliative treatment modality in
dogs with nasal
SCCs . -
pubmed
ANIMALS : Ten client - owned
dogs with nasal
SCC were included : seven neutered
males , two spayed females and one intact male , with a median age of 12.5 years ( range 9 - 15 years ) . -
pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : Combined
CO2 laser and cryosurgical ablation was practical , cost - effective and provided an excellent aesthetic outcome in
dogs with
SCCs restricted to the nasal septum , while providing acceptable palliation of local disease . -
pubmed
We present 40
patients ( 30
males , 10
females ; mean age 25 years ) diagnosed and treated for
CB of the foot from 1975 to 2012 . -
pubmed
Ten
patients ( 25 % ) had secondary
aneurysmal bone cyst . -
pubmed
In conclusion ,
patients with
CB of the foot are usually older than 20 years , and males are most affected . -
pubmed
BACKGROUND :
Children with
Kawasaki disease (
KD ) and
pyuria have been misdiagnosed with
urinary tract infection (
UTI ) . -
pubmed
METHODS : We retrospectively reviewed the medical records of
children with
fever who were under 6 months of age with
pyuria , over a 10 - year period ( 2007 - 2017 ) . -
pubmed
RESULTS : During the period investigated , 12 ( 9.9 % )
KD patients with sterile
pyuria and 378 infants with
UTI were included in this study . -
pubmed
Combined Therapy With Functional Electrical Stimulation and Standing Frame in
Stroke Patients . -
pubmed
Thus , the proposed combined therapy could be a useful method for improving standing balance in
subacute stroke patients . -
pubmed
In our case , a 34 - year - old female
patient presented with
paresthesia of the third digit . -
pubmed
METHODS :
Patients with nonmetastatic
breast cancer receiving active adjuvant ET were approached by nurse practitioners to complete an anonymous survey at one time point . -
pubmed
MATERIALS AND METHODS : We reviewed a prospectively collected database from March 1998 through June 2016 for
patients who underwent
holmium laser enucleation of the prostate for symptomatic
benign prostatic hyperplasia as performed or supervised by a single expert surgeon . -
pubmed
Postoperative complications included
urethral stricture and
bladder neck contracture in 21 ( 1.4 % ) and 30
patients ( 2.1 % ) , respectively . -
pubmed
However , both doses of
FGY-1153 treatment decreased left ventricular ( LV )
hypertrophy and
diastolic dysfunction in
hypertensive animals . -
pubmed
Analysis of the therapeutic effect of transesophageal echocardiography - guided percutaneous device closure of
atrial septal defects via the right internal jugular vein in
children . -
pubmed
METHODS : Nineteen pediatric
patients with secondary
ASD underwent TEE - guided ASD device closure via the RIJV from July 22 , 2015 to July 19 , 2017 . -
pubmed
RESULTS : In all 19
patients , the
ASDs were successfully closed and the occluder was confirmed to have a stable position and good shape , with no residual shunt . -
pubmed
This procedure has varied indications , and its advantages include a short operation path , procedural accuracy , minimal
trauma , and quick recovery , especially for young
patients with large
ASDs and cases in which a femoral vein approach is difficult . -
pubmed
MATERIALS AND METHODS : All
patients with
VAP in whom
ABT was stopped before
death or discharge were included in this 5 - year prospective cohort study . -
pubmed
RESULTS : We included 157 of the 316
patients with microbiologically - proven
VAP . -
pubmed
CONCLUSIONS : PCT - guided
ABT adherence appears safe for
patients with
VAP and is likely to reduce exposure to antibiotics . -
pubmed
Our study provides insights on how
pig diseases can be spread between
pig farms via direct and indirect contact in Nghe An under the various hypothetical scenarios . -
pubmed
[ Network meta - analysis on the effects of the acupuncture - related therapy on ovulation rate and pregnancy rate in
patients with
polycystic ovary syndrome ] . -
pubmed
OBJECTIVE : To review systematically the safety and effectiveness of acupuncture - related therapies on ovulation rate and pregnancy rate in
patients with
polycystic ovary syndrome (
PCOS ) . -
pubmed
Eight - week - old male
Wistar rats weighing 200 - 250 g were induced with
hyperlipidemia via a high - fat diet ( HFD ) comprising 40 % beef tallow . -
pubmed
RESEARCH DESIGN AND METHODS : Twenty - eight
volunteers with
diabetes (
BMI 32.4 + - 5.2 kg / m2 and HbA1c 8.1 + - 1.1 % [ 64.5 + - 11.9 mmol / mol ] ) were randomly assigned to 3Mdiet or 6Mdiet . -
pubmed
Predicting
variceal bleeding in
patients with
biliary atresia . -
pubmed
The aim of this study is to predict high - risk
varices by analyzing various clinical factors , thus improve prognosis of
patients with
biliary atresia . -
pubmed
In this study we investigated the clinicopathologic and molecular features of 7
patients presenting with
primary osseous SEF . -
pubmed
2,6 - diisopropylphenol (
propofol ) is a commonly used intravenous anesthetic drug , which has been reported to serve an antitumor role in
human cancers . -
pubmed
The current study aimed to assess the effects of
propofol on the biological behaviors of
human bladder cancer cells and to elucidate its potential molecular mechanism . -
pubmed
DIAGNOSIS : The
patient was first diagnosed with
macular hole , which closed spontaneously . -
pubmed
OUTCOMES : The
patient first exhibited a
macular hole , which resolved spontaneously . -
pubmed
METHODS : We compared the skew of the distribution of power values from five minutes non - rapid eye movement stage N3 sleep for the 5 - 80 Hz , 80 - 250 Hz ( ripple ) , and 250 - 500 Hz ( fast ripple ) bands of
epileptic ( located in
seizure - onset or irritative zone ) and non -
epileptic iEEG channels recorded in
patients with
drug - resistant focal epilepsy . -
pubmed
External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in
women with ductal
carcinoma in situ and node - negative
breast cancer ( RAPID ): a randomised controlled trial . -
pubmed
Women aged 40 years or older with ductal
carcinoma in situ or node - negative
breast cancer treated by breast conserving surgery were randomly assigned ( 1:1 ) to receive either external beam APBI ( 38 5 Gy in ten fractions delivered twice per day over 5 - 8 days ) or whole breast irradiation ( 42 5 Gy in 16 fractions once per day over 21 days , or 50 Gy in 25 fractions once per day over 35 days ) . -
pubmed
Acute radiation
toxicity ( grade > = 2 , within 3 months of radiotherapy start ) occurred less frequently in
patients treated with APBI ( 300 [ 28 % ] of 1070
patients ) than whole breast irradiation ( 484 [ 45 % ] of 1065
patients , p<0 0001 ) . -
pubmed
Late radiation
toxicity ( grade > = 2 , later than 3 months ) was more common in
patients treated with APBI ( 346 [ 32 % ] of 1070
patients ) than whole breast irradiation ( 142 [ 13 % ] of 1065
patients ; p<0 0001 ) . -
pubmed
Efficacy of the
plantago major L. syrup on radiation induced
oral mucositis in
head and neck cancer patients : A randomized , double blind , placebo - controlled clinical trial . -
pubmed
INTRODUCTION : Oral
mucositis is a complication of radiation therapy in
cancer patients . -
pubmed
We designed a trial to evaluate efficacy of
plantago major on symptoms of radiation induced
mucositis in
cancer patients . -
pubmed
Outcome measures were severity of
mucositis according to WHO scale and severity of
patients '
pain assessed by visual analogue scale . -
pubmed
Also
patients in intervention group experienced significantly less
pain compared to placebo group during radiotherapy period ( p value<0.05 ) CONCLUSION :
Plantago major L syrup was effective on the reduction of the symptoms of radiation induced
mucositis in
patients with
head and neck cancers . -
pubmed
Surface modified
PAMAM dendrimers with
gallic acid inhibit , cell proliferation , cell migration and inflammatory response to augment apoptotic cell
death in
human colon carcinoma cells . -
pubmed
Gain of 1q21 is an adverse prognostic factor for
multiple myeloma patients treated by autologous stem cell transplantation : A multicenter study in China . -
pubmed
BACKGROUND : Autologous stem cell transplantation ( ASCT ) has been recommended as a standard approach for young
multiple myeloma (
MM )
patients for decades , even in the era of novel agents . -
pubmed
METHODS : In this multicenter study , we retrospectively analyzed 1q21 gain in 446 newly diagnosed
MM patients who received at least one ASCT from three large
myeloma centers in China . -
pubmed
CONCLUSION : In conclusion , 1q21 gain is an adverse prognostic factor for
MM patients received ASCT . -
pubmed
METHOD : A cross - sectional study was conducted on a total of 61
patients with confirmed
Trigeminal neuralgia visiting outpatient neurology clinics of two government teaching Hospitals and two private health facilities in Addis Ababa , Ethiopia between June 2019 and March 2020 . -
pubmed
OBJECTIVE : To establish the reliability of the Global Postural System ( GPS ) in assessing pelvic asymmetry and identify the association between pelvic asymmetry parameters and the occurrence of
NCLBP in young
adults . -
pubmed
METHODS :
People who were aged between 18 and 30 and were diagnosed with
NCLBP were recruited . -
pubmed
Diagnostic and prognostic considerations for use of natriuretic peptides in obese
patients with
heart failure . -
pubmed
Nobiletin as a nontoxic dietary
citrus flavonoid has anticancer effects in
cancer . -
pubmed
Here , we investigated the therapeutic potential of XA for
rheumatoid arthritis (
RA ) , a debilitating
autoimmune inflammatory disease characterized by
joint damage , in the complete Freund 's adjuvant ( CFA)-induced
arthritis model in
rats . -
pubmed
AIM To investigate if clinically appropriate renal function monitoring is being undertaken in New Zealand primary care for
stroke prevention in non - valvular
atrial fibrillation patients prescribed
dabigatran etexilate . -
pubmed
DISCUSSION There appears to be sub - optimal adherence to renal function monitoring for non - valvular
atrial fibrillation patients who receive more than 12 - months ' treatment with
dabigatran etexilate in New Zealand primary care . -
pubmed
This case - control study enrolled 85
children with
ADHD and 96 control subjects . -
pubmed
Children with
ADHD had significantly higher
DMP ( 238.95 nmol / g cre . -
pubmed
coli W
strains are much lower than those from the
strains of
E. - pubmed
Selective
hypoxia on the left lower lobe of the lung in open - chested
dogs at 37 degrees C caused the electromagnetically measured blood flow to the lobe to decrease 51 + /- 5 ( SE)% and its vascular resistance to increase 155 + /- 25 % . -
pubmed
However , high
slide falciparum rate ( 51.57 ) , child parasite rate ( 40.0 ) , infant parasite rate ( 66.66 ) and spleen rate ( 82.90 ) in the village clearly indicated hyperendemic conditions in the area and hence
deaths recorded in the village during the
malaria transmission period could be due to
malaria only . -
pubmed
The studies were carried out in a group of 52
asthmatic patients . -
pubmed
We report a
patient with a
keratoacanthoma of the scalp in which there was invasion of several medium - sized vessels by the
tumour at a distance from the main lesion . -
pubmed
Apoptosis of
murine BW 5147 thymoma cells induced by cold
shock . -
pubmed
Twenty - five
patients with clinical
relapse after previous successful angioplasty of iliac or femoro - popliteal arteries were evaluated with repeat angiography . -
pubmed
Enzyme activity was measured in 84 normal
subjects and in 109
patients with common
metabolic bone diseases . -
pubmed
The
patients in group 3 did not require treatment for
pruritus or
nausea , a response significantly different ( P less than 0.001 and P less than 0.05 , respectively ) from group 1 or group 2. -
pubmed
These results suggested that deficiencies in the
HCMV - specific antibody response were not associated with clinically apparent
congenital infection and that other factors , such as early virus acquisition during pregnancy , might contribute to the severity of
intrauterine HCMV infection . -
pubmed
PLS formation appears to indicate a
CMI response to
M. - pubmed
It is thought that there exists a correlation between the
PLS and the lymphocyte transformation test ( LTT ) , both reaching their optimum measurement three months after the
M. - pubmed
Body composition , sleeping metabolic rate ( SMR ) , 24 - h energy expenditure ( 24 - EE ) and daily physical activity were determined in 12
obese women during and after 12 weeks of exercise ( 4 h per week on 55 per cent of VO2 max ) and/or energy restriction ( 2.9 - 3.5 MJ / d ) . -
pubmed
Numerical index of the discriminatory ability of biotyping for
strains of
Salmonella typhimurium and
Salmonella paratyphi B. -
pubmed
Three collections of phage - typed
strains of
Salmonella typhimurium and
Salmonella paratyphi B , previously tested for biotype , were examined . -
pubmed
These findings confirm that biotyping affords excellent discrimination of
strains of
S. - pubmed
DBA
mice , susceptible to
audiogenic seizures (
AGSs ) in an age - dependent manner , have increased CA activity as compared with C57 ( non - audiogenic
seizure susceptible )
mice at 21 and 110 days of age . -
pubmed
ACTZ ED50s against maximal electroshock
seizures (
MES ) were significantly higher in DBA as compared with C57
mice at 26,36 , and 115 days of age . -
pubmed
The life events experienced in the 12 months prior to the first
panic attack were studied in 23
patients with a DSM - III diagnosis of
panic disorder as well as in 23 healthy subjects matched for age , sex , social and educational level . -
pubmed
This normal response in our
patients demonstrates that the
hypotestosteronaemia in Indian men with
myocardial infarction is not due to a primary
testicular dysfunction but probably is a result of increased aromatization of
testosterone to
oestradiol . -
pubmed
Between 1970 and 1981 we saw 108
patients with
vulvar carcinoma stages I - IV at the university clinic of Graz . -
pubmed
A study undertaken to determine the Onchocerca species infecting
camels that live in the same localities as
cattle in the Dinder Region , Blue Nile Province , Sudan revealed concurrent
infections with the bovine parasites
Onchocerca armillata in the thoracic aorta , brachiocephalic trunks and brachial arteries and
Onchocerca gutturosa in the ventral side of the lamellar parts of the ligamentum nuchae . -
pubmed
Babe Ruth ,
tobacco ,
alcohol , and
cancer . -
pubmed
An ultrasound study of the thyroid was performed in 55
patients who were admitted to be treated surgically for the
goiter . -
pubmed
Sixty - six
patients were admitted from January 1980 through December 1983 with double
fractures of the pelvic ring that involved the posterior elements . -
pubmed
We conclude that the
patient with multiple
trauma without unstable
pelvic fracture should undergo immediate external fixation to decrease morbidity and mortality rates and limit soft tissue damage . -
pubmed
[ Motor - evacuatory function of the gastrointestinal tract in
patients with
dumping syndrome ] . -
pubmed
The efficacy of
2 - chloro-4 - nitrobenzamide for the prevention and control of
coccidiosis in
chickens . -
pubmed
Factors affecting testis weight in normal and
cryptorchid horses . -
pubmed
Effect of volume expanders on the lysability of ex vivo
thrombi in the
rabbit . -
pubmed
Chironomids , of which approximately 10,000 species exist , are reported to cause severe immediate type
allergic diseases in
man . -
pubmed
Selenium suppresses the metabolism of
benzo [ a ] pyrene by
rat - liver extracts , and exerts a dual effect on its
mutagenicity . -
pubmed
Effect of diet on
human muscle weakness following prolonged exercise . -
pubmed
It is concluded that changes in muscle glycogen alone do not alter the isometric force generating capacity of
human muscle , but when combined with prolonged exercise low muscle
glycogen enhances exercise - induced
muscle weakness . -
pubmed
In nine healthy
subjects a 2 %
calcium solution was continuously infused intravenously and a
hypercalcaemic state was maintained . -
pubmed
Isolation , characterization and biological activities of
verotetrone from a mutant
strain of
Streptomyces aureofaciens . -
pubmed
A new metabolite denoted as
verotetrone was isolated from the mycelium of the mutant
strain Streptomyces aureofaciens NMG-2 . -
pubmed
Thirty - nine
patients with invasive
bladder cancer were treated using a new approach to adjuvant radiation therapy . -
pubmed
The clinical records of 61
patients who underwent extended surgery , including resection of parietes or other viscera , from 1965 to 1977 for
cancer of the rectum and sigmoid were reviewed . -
pubmed
Local or distant
recurrence occurred in 66 per cent of
patients with microscopic infiltration and in 24 per cent of
patients without microscopic infiltration . -
pubmed
Induction of anti - tubular- and anti - glomerular - basement - membrane antibodies in
guinea pigs sensitized to
2 , 4 - dinitrochlorobenzen with reference to tubulo - interstitial and
glomerular nephritis . -
pubmed
Cells that grew in soft agar also produced undifferentiated
mesenchymal tumors in preirradiated
nude mice . -
pubmed
HR 466 (
16 , 16 - dimethyl-18 - oxa - PGA2 ) , the best compound out of this series was active for 5 - 6 hours after oral administration of 0 , 1 mg / kg to conscious renal
hypertensive dogs . -
pubmed
Structural variations within the
trans - delta 2 - 11 - deoxy - PGE1 - series , in both side chains , gave HR 601 (
trans - delta2 - 15alpha - acetoxy-16 , 16 - dimethyl-18 - oxa-11 - deoxy - PGE1 - methylester ) which was orally active in the
hypertensive dog with similar activity to HR 466 . -
pubmed
Fatal
haemoptysis in
Salmonella typhimurium septicaemia -- a cautionary tale . -
pubmed
Septicaemia and
mycotic aneurysm may occur in a patient who is an enteric - carrier of
Salmonella typhimurium . -
pubmed
We report such a case of an elderly
man who presented with
chest pain and fatal massive
haemoptysis from a likely
mycotic thoracic aneurysm . -
pubmed
Toxicity of
myristic acid analogs toward
African trypanosomes . -
pubmed
Patients were
seizure - free and did not show EEG abnormalities at repeated controls in the last 5 years , so that interfering effects of
seizures were possibly excluded . -
pubmed
[ Current problems in the intensive therapy of
patients with
acute pneumonia ] . -
pubmed
Chronic hepatitis , representing the category which could benefit from
interferon alpha treatment , was found in 24
patients . -
pubmed
Severe complications of the
hepatitis were found in 4 % of the
children , including
hepatocellular carcinoma and
cirrhosis . -
pubmed
Platelet - activating factor antagonist
BN52021 improves survival in normothermic
liver ischemia in
rats . -
pubmed
The
human microvascular anastomosis represents a localized environment with strongly
thrombotic tendencies . -
pubmed
In order to evaluate the prevalence and the clinical manifestations of this complication , all
patients with spontaneous
pneumothorax managed with chest tube drainage were evaluated over an 8 - yr period ( 1986 - 1994 ) . -
pubmed
A 43 - year - old
man suffered generalized
convulsions following severe
headache . -
pubmed
METHODS : One hundred
women with pure
stress urinary incontinence were enrolled in a 6 - month study . -
pubmed
Bothersome
vaginal or urethral irritation occurred in 12 % of
patients . -
pubmed
Differences in extracellular matrix components and cell density during normal and
dexamethasone - treated secondary palate development in two
strains of
mice with different susceptibility to glucocorticoid induced - clefting . -
pubmed
An histological and histochemical study analyzing cell density and distribution of extracellular matrix ( ECM ) components in two stages of developing secondary palate and in two
strains of
mice with different H-2 backgrounds was undertaken to investigate differences between a
strain that is susceptible to glucocorticoid - induced
cleft palate (
A / Sn ) and one that is resistant ( C57 / BL ) . -
pubmed
fragilis group ( from 14 % in 1992 to 29 % in 1996 ) and also among
strains of clostridia ( 32 % ) ,
P. - pubmed
A phase II trial of
interferon alpha-2a and
carboplatin in
patients with advanced
malignant mesothelioma . -
pubmed
We defined the antitumor activity , toxicity , and tolerability of a combined chemoimmunotherapy approach in
patients with advanced
malignant mesothelioma using daily low - dose
interferon alpha-2a and
carboplatin given every 4 weeks . -
pubmed
This was a phase II study of 15
patients with surgically unresectable or metastatic
malignant mesothelioma . -
pubmed
Fifteen
patients were assessable for
toxicity and 14 for response . -
pubmed
Forty - four
patients were referred because of
myocardial ischemia related to the stented artery . -
pubmed
There is also an urgent need to update existing guidelines and perhaps even provide specific guidelines for the treatment and long - term management of
patients with
diabetes and
hypertension . -
pubmed
These unique properties of the 14 - repeat allele may confer selective advantages in
diabetic individuals , which may delay or prevent microvascular complications of
diabetes . -
pubmed
BACKGROUND AND PURPOSE : To define the effects of three commonly used anesthetic agents --
sodium pentobarbital given intraperitoneally , and inhaled
halothane and
methoxyflurane -- on the pathogenesis of
pneumococcal pneumonia and
bacteremia in an experimental
murine model . -
pubmed
METHODS : Swiss outbred
mice were anesthetized with either
sodium pentobarbital ,
halothane , or
methoxyflurane before intranasal
infection with
Streptococcus pneumonia . -
pubmed
CONCLUSION : Effects of anesthesia on
murine models of
pneumonia should be considered in the design and interpretation of studies of
pneumococcal pathogenesis . -
pubmed
Based on DNA relatedness data , the type
strains of
Thermoactinomyces intermedius ,
Thermoactinomyces putidus ,
Thermoactinomyces dichotomicus and
Thermoactinomyces peptonophilus were considered to be distinct species of the genus Thermoactinomyces . -
pubmed
However , the relationship between the type
strains of
Thermoactinomyces vulgaris and
Thermoactinomyces candidus and the relationship between the type
strains of
Thermoactinomyces sacchari and
Thermoactinomyces thalpophilus were reevaluated from levels of DNA - DNA relatedness . -
pubmed
Eight
atherosclerotic male adult
New Zealand White rabbits weighing 4 - 6 kg were used in these studies . -
pubmed
Viral co - infection does not reduce the efficacy of vaccination against non - typeable
Haemophilus influenzae middle ear infection in a
rat model . -
pubmed
Our results suggest that high - dose
aspirin exerts significant
toxicity to
guinea pig myocardium and normal dose
aspirin may cause peroxidation in the
human erythrocytes due to its oxidant potential . -
pubmed
METHODS :
Tumors were established in the floor of mouth in
C3H / HeJ immunocompetent mice . -
pubmed
Comparative analysis of two - dimensional protein patterns in
malignant and
normal human breast tissue . -
pubmed
Malignant and
normal human breast tissue were compared by evaluating two - dimensional
polyacrylamide gel electrophoresis ( 2D - PAGE ) maps of frozen tissue samples . -
pubmed
We report the case of a 90 - year - old
diabetic patient who developed simultaneous
avulsions of the patellar and tibial insertions . -
pubmed
CASE REPORT : A 90 - year - old
woman with
noninsulin - dependent diabetes mellitus fell on her left knee and was subsequently unable to extend the knee despite normal quadriceps contraction . -
pubmed
DISCUSSION : Bifocal
disruption of the extensor system is a rare event in
adults . -
pubmed
In fact , strongly reactive TA - specific cytolytic T - lymphocytes and tumour - infiltrating lymphocytes ( TIL ) can be identified and expanded ex vivo from
patients with
metastatic melanoma vaccinated with
melanoma - associated antigens . -
pubmed
METHODS : Resting electroencephalogram was recorded in 38 unmedicated
subjects with
major depressive disorder and 18 normal comparison subjects , and analyzed with a tomographic source localization method that computes the cortical three - dimensional distribution of current density for standard electroencephalogram frequency bands . -
pubmed
In melancholic
subjects , this effect was particularly pronounced for severe
depression , and right frontal activity correlated positively with
anxiety . -
pubmed
This metabolic footprint was relatively constant in all
patients regardless of age ,
seizure history , or therapies and therefore constitutes a radiological signature of the disease . -
pubmed
All macaques , including one naive
macaque , were exposed to SIV(mac251 ) by the intrarectal route and sacrificed 48 h after
infection . -
pubmed
Effect of
vitamin C supplementation on reduced
glutathione and
malondialdehyde in
patients with
acute myocardial infarction . -
pubmed
Individuals with
Williams syndrome typically show relatively poor visuospatial abilities in comparison to stronger verbal skills . -
pubmed
Individuals with
Williams syndrome show an atypical processing style on tests of construction , which does not affect tests of perception . -
pubmed
Staphylococcus epidermidis is the most frequent cause of
nosocomial sepsis and
catheter - related infections , in which biofilm formation is considered to be the main virulence mechanism . -
pubmed
Reduction of cardiac output by ligation of the inferior vena cava in
patients with
atrial septal defects complicated by
pulmonary hypertension ; a report of 2 cases . -
pubmed
Studies on the effect of beers of
Penicillium funiculosum against
Columbia SK virus infections in
mice . -
pubmed
[ Important stages and aspects in the study of
human brucellosis abroad and in the USSR . -
pubmed
( 100th anniversary of the differentiation of
brucellosis as a new
human disease ) ] . -
pubmed
In male
rats , pretreatment for 20 days with very low ( 0.5 , 1 % , v / v ) but not with high ( 5 , 10 % , v / v ) oral doses of
ethanol delayed the initiation and reduced the duration of
narcosis induced by an acute high intraperitoneal ( i.p . ) -
pubmed
A higher dose of
sulpiride ( 10 mg / kg ) prolonged the duration of
narcosis in
rats pretreated with high - dose
ethanol and reduced the number of conditioned avoidance responses in the shuttle - box paradigm . -
pubmed
First in vivo measurements of DAT with single photon emission computed tomography ( SPECT ) in
ADHD patients revealed an elevation of striatal DAT density . -
pubmed
No differences in DAT density between the left and right side and between putamen and caudate nucleus have been found in
[ 99mTc ] TRODAT-1 SPECT of
ADHD patients . -
pubmed
Patients with
ADHD and with a history of
nicotine abuse both displayed lower values of DAT density in
[ 99mTc ] TRODAT-1 SPECT than non - smokers with
ADHD . -
pubmed
DAT seem to be elevated in non - smoking
ADHD patients suffering from the purely inattentive subtype of
ADHD as well as in those with the combined or purely hyperactive / impulsive subtype . -
pubmed
This study assessed the efficacy and safety of liraglutide after 12 weeks of treatment in
type 2 diabetic patients . -
pubmed
RESEARCH DESIGN AND METHODS : A double - blind , randomized , parallel - group , placebo - controlled trial with an open - label comparator arm was conducted among 193
outpatients with
type 2 diabetes . -
pubmed
Patients treated with
glimepiride had decreased HbA(1c ) and fasting
glucose , but slightly increased
body weight . -
pubmed
METHODS : In a nationwide study on
JT , 123
patients were re - examined 10 y ( range 4 to 21 y ) after diagnosis . -
pubmed
Two
patients with toxic
adenoma were excluded . -
pubmed
AIMS / HYPOTHESIS : The aim of this study was to assess whether the diabetogenicity of
areca nut (
Areca catechu or '
betel - nut ' ) , which has previously been demonstrated experimentally in
mice , independently contributes to the risk of
hyperglycaemia or
type 2 diabetes in men in Taiwan , where the habit has become established relatively recently . -
pubmed
RESULTS : Compared with non - chewers ,
areca nut chewers had higher age - adjusted prevalence rates for
hyperglycaemia ( 11.4 % vs 8.7 % ) and
type 2 diabetes ( 10.3 % vs 7.8 % ) . -
pubmed
Extracellular enzymatic activity and serotype of
Cryptococcus neoformans strains isolated from
AIDS patients in Brazil . -
pubmed
External
otitis caused by
infection with
Pseudomonas aeruginosa or
Candida albicans cured by use of a topical group III
steroid , without any antibiotics . -
pubmed
CONCLUSIONS : Irrespective of the microbial agent , group III
steroid solution cured external
otitis efficiently in a
rat model . -
pubmed
OBJECTIVE : External
otitis , caused by
infection with either
Pseudomonas aeruginosa or
Candida albicans , was established in a
rat model and the treatment efficacy of a group III
steroid solution was studied . -
pubmed
Transport deficient ( TR- )
hyperbilirubinemic rats are resistant to
acetaminophen hepatotoxicity . -
pubmed
This mutant
strain of
Wistar rats has impaired biliary excretion of organic anions and increased hepatic
glutathione . -
pubmed
Therefore , the susceptibility of TR-
rats to
APAP hepatotoxicity was investigated . -
pubmed
TR-
rats treated with
buthionine sulfoximine and
APAP showed dramatic increases in
hepatotoxicity . -
pubmed
A total of 53 consecutive
patients , 34 with early
MI ( group 1 ) and 19 with recent
MI ( group 2 ) , who had had no prior thrombolytic therapy were included . -
pubmed
Therefore , investigation of longer utilization of anti - platelet and anti - inflammatory agents for
patients following
AMI might be worthwhile . -
pubmed
It has been shown that there is an increased proportion of T regs in several different
human malignancies , although the actual mechanism remains unclear . -
pubmed
The aim of this study was to determine the prevalence of
Mycoplasma genitalium in
male urethritis and in vaginal specimens of pregnant women . -
pubmed
Urethral specimens obtained from 37 men presenting with
urethritis and vaginal specimens from 50 consecutive pregnant women were tested for the presence of
M. - pubmed
The urethral specimens were also examined for the presence of
Neisseria gonorrhoeae ,
Chlamydia trachomatis and
Ureaplasma sp whereas the vaginal microbiota and the presence of
genital mycoplasma were investigated in the vaginal specimens . -
pubmed
Serotonin and
5 - hydroxy - indole - acetic acid contents in dorsal raphe and suprachiasmatic nuclei in normal , malnourished and rehabilitated
rats under 24 h of
sleep deprivation . -
pubmed
Then , all
animals were sacrificed by
decapitation . -
pubmed
BACKGROUND : The management of
patients with
colorectal cancer has changed appreciably over the last 16 years . -
pubmed
This data was compared with a retrospective data set that included all
patients treated with
colorectal cancer at the same institution from 1989 to 1995 . -
pubmed
There were more
patients with
rectal cancer and stage I
cancer in the study group . -
pubmed
and a decrease in the 5 year
recurrence rate for
patients undergoing curative resections ( 17 % [ 95 % CI 12%-20 % ] vs 42 % [ 95 % CI 36%-49 % ] , p & lt ; 0.001 ) . -
pubmed
There was also a decrease in local
recurrence in
patients with rectal
cancer ( 8.8 % [ 95 % CI 4.5%-13.1 % ] vs 33.6 % [ 95 % CI 23.6%-43.6 % ] , p & lt ; 0.001 ) . -
pubmed
Q
fever is a worldwide - occurring
zoonosis caused by
Coxiella burnetii . -
pubmed
Whereas serology is the reference diagnostic method for
Q fever , detection of
C. - pubmed
These results are the first to report alterations in expression of muscle - enriched microRNAs in skeletal muscle of the mdx
mouse , suggesting microRNAs may have a role in the pathophysiology of
muscular dystrophy . -
pubmed
We operated 52
patients ranging in age from 29 to 60 , who presented with
prolapse of the nucleus pulposus ( 21
patients ) , instability ( 8 patients ) ,
lumbar stenosis ( 11
patients ) , and recurrent
discopathy with
spondylolisthesis ( 12
patients ) . -
pubmed
Cytotoxicity , metabolism and cellular uptake of the mycotoxin
deoxynivalenol in
human proximal tubule cells and lung fibroblasts in primary culture . -
pubmed
At the level of the whole
animal , the toxic effects of the mycotoxin
deoxynivalenol (
DON ) range from causing
diarrhoea ,
vomiting ,
gastro - intestinal inflammation to
necrosis of several tissues . -
pubmed
Although
DON has been tested in different
human and animal cell lines for its
cytotoxicity , these tests might be limited due to the disadvantages of cell lines ( e.g. -
pubmed
It could be demonstrated that
DON has a distinct
cytotoxic effect on
human primary cells . -
pubmed
In the Natalizumab Safety and Efficacy in
Relapsing - Remitting Multiple Sclerosis ( AFFIRM ) trial , infusion - related
hypersensitivity reactions developed in 4 % of
patients , usually within 2 hours after starting the infusion . -
pubmed
PATIENT : A 23 - year - old
man with relapsing - remitting
multiple sclerosis developed a
fever ,
arthralgias ,
urticarial exanthema , and a
swollen lower lip during several days after his second infusion of
natalizumab . -
pubmed
RESULTS : The
patient developed a delayed ,
serum sickness - like ,
type III systemic allergic reaction to
natalizumab . -
pubmed
CONCLUSION : Clinicians and
patients should be alert not only to immediate but also to significantly delayed substantial
allergic reactions to natalizumab . -
pubmed
Safety and immunogenicity profile of the concomitant administration of ZOSTAVAX and inactivated
influenza vaccine in
adults aged 50 and older . -
pubmed
OBJECTIVES : To evaluate the safety and immunogenicity of ZOSTAVAX administered concomitantly with inactivated
influenza vaccine or sequentially in
adults aged 50 and older . -
pubmed
Estimated GMT ratios ( concomitant / sequential ) for
influenza strains A(H1N1 ) ,
A ( H3N2 ) , and B were 0.9 ( 95 % CI=0.8 - 1.1 ) , 1.1 ( 95 % CI=0.9 - 1.3 ) , and 0.9 ( 95 % CI=0.8 - 1.1 ) , respectively , and SCRs were comparable across both groups , with more than 85 % achieving titers of 1:40 or greater , meeting regulatory criteria . -
pubmed
As a new approach , we evaluated the protolerogenic potential of
calcitriol and
dexamethasone in acute T helper ( Th)1 - mediated
colitis in
mice . -
pubmed
Lymphangitis in a Portuguese patient infected with
Rickettsia sibirica . -
pubmed
OBJECTIVE :
Congenital hyperinsulinism , usually associated with severe
neonatal hypoglycemia , may progress to
diabetes , typically during the 4th decade of life in nonpancreatectomized
patients . -
pubmed
We aimed to genotype the
ATP - sensitive K(+ ) channel in a 10.5 - year - old
girl presenting with overt
diabetes following
hyperinsulinism in infancy . -
pubmed
RESEARCH DESIGN AND METHODS : A
female aged 10.5 years presented with new - onset , antibody - negative
diabetes (
A1C 10.6 % ) . -
pubmed
In this study the authors examined the efficacy of
TUDCA on preserving rod and cone function and morphology at postnatal day 30 ( P30 ) in the rd10
mouse , a model of
RP . -
pubmed
CONCLUSIONS :
TUDCA is efficacious and safe in preserving vision in the rd10
mouse model of
RP when treated between P6 and P30 . -
pubmed
At P30 , a developmental stage at which nearly all rods are absent in the rd10
mouse model of
RP ,
TUDCA treatment preserved rod and cone function and greatly preserved overall photoreceptor numbers . -
pubmed
Escape behaviour in
rodents closely mimics
panic attacks in
humans . -
pubmed
This study evaluates the effects of age and chronic dietary restriction ( DR ) on
nonneoplastic diseases in
rats that were fed the American Institute of Nutrition ( AIN)-93 M purified diet . -
pubmed
Nonneoplastic disease profiles were developed to clarify whether the AIN-93 M diet fulfills long - term nutritional requirements of
rats . -
pubmed
At 58 weeks of age , the 2 main types of
nonneoplastic diseases in AL
rats were
liver vacuolization and
cardiomyopathy . -
pubmed
At 114 weeks of age , the most common lesions in AL
rats were
cardiomyopathy ,
nephropathy ,
liver vacuolization , and degeneration with
renal failure and
genitourinary infections causing the greatest mortality . -
pubmed
Nonneoplastic diseases accounted for 28.9 % and 0.0 % of total mortalities in the AL and DR groups , respectively ; however , there was a higher incidence of unknown
deaths in the DR
rats ( 52.6 % ) compared to AL
rats ( 28.9 % ) , which may have limited the success of DR to improve survival . -
pubmed
Although the AIN-93 M diet supported chronic
rat growth , alterations in some dietary component concentrations may be required to lower
body weight in chronic
rodent and
human studies . -
pubmed
Factors such as diet composition and digestibility may alter
nonneoplastic diseases and mortality in
rats and
humans in a similar fashion . -
pubmed
These lower the efficiency of treatment , increase the likelihood of drug resistance in
Mycobacterium tuberculosis , and contribute to the chronic pattern of the
tuberculosis process , continuously replenishing the pool of untreatable patients with
tuberculosis and bacterial discharge . -
pubmed
After 6 week period of the renal artery clipping procedure , eight 2K1C
rats developed stable
hypertension . -
pubmed
The differences between the
hypertensive rats and the control group concerned not only the number of endocrine cells but also their distribution . -
pubmed
Flokalin was introduced in dose 0.1 mg / kg of
animal body weight which practically did not change the parameters of hemodynamic in conditions of normoxia . -
pubmed
Immunization against a
lymphoid tumor of the
chicken ; use of miscellaneous tissues . -
pubmed
Resistance to multiple drugs is a serious limitation to chemotherapy treatment of
human cancers . -
pubmed
RESULT :
children with
sensorineural and conductive hearing loss presented a lower performance in all of the SAAT results when compared to the control group . -
pubmed
Stimulus similarity and encoding time influence incidental recognition memory in adult
monkeys with selective
hippocampal lesions . -
pubmed
Recognition
memory impairment after selective
hippocampal lesions in
monkeys is more profound when measured with visual paired - comparison ( VPC ) than with delayed nonmatching - to - sample ( DNMS ) . -
pubmed
To clarify this issue , we assessed the impact of stimuli similarity and encoding duration on the VPC performance in
monkeys with
hippocampal lesions and sham - operated controls . -
pubmed
Persistent epithelial barrier alterations in a
rat model of
postinfectious gut dysfunction . -
pubmed
CONCLUSIONS & amp ; INFERENCES :
Trichinella spiralis infection in
rats , at late stages , results in persistent postinfectious intestinal barrier dysfunctions and mucosal
mastocytosis , with other signs suggestive of a low grade
inflammation . -
pubmed
CASE REPORT : We report the case of a 35 - year - old
man who presented with symptoms of acalculous
gallbladder disease with high levels of
amylasuria . -
pubmed
METHODS : Between April 2006 and February 2010 , we performed laparoscopic resection for
SMTs located near the EGJ ( within 3.0 cm from the EGJ ) in ten consecutive
patients . -
pubmed
Out of seven exogastric resections , an FRT was used in five
patients with posterior
tumors near the EGJ . -
pubmed
It was examined a cohort of
patients with
cystic fibrosis of the southern Italy , 24
patients aged between 12 and 44 years , 12 females and 12 males with
BMD assessment methods like dual energy X - rays ( DXA ) and calcaneal ultrasound densitometry in a few cases , ultrasonography was used jointly . -
pubmed
[ The role of
hypercholesterolemia in the outbreak of
Alzheimer ' s disease and the treatment effect of
Sibraea angustata extract ] . -
pubmed
OBJECTIVE : To observe the role of
hypercholesterolemia in the outbreak of
Alzheimer ' s disease (
AD ) and the treatment effect of
Sibraea angustata extract . -
pubmed
The extract of
Sibraea angustata can not only reduce the content of
cholesterol in the
AD animal effectively but also improve brain tissue pathology . -
pubmed
Genetic diversity of clinical and environmental
Vibrio parahaemolyticus strains from the Pacific Northwest . -
pubmed
Since 1997 , cases of
Vibrio parahaemolyticus - related
gastroenteritis from the consumption of raw oysters harvested in Washington State have been higher than historical levels . -
pubmed
Production and degradation of extracellular matrix in reversible
glomerular lesions in
rat model of
habu snake venom - induced
glomerulonephritis . -
pubmed
We investigated the mechanism of development and repair process of
glomerular injury in a
rat model of
habu snake (
Trimeresurus flavoviridis ) venom ( HSV)-induced
glomerulonephritis . -
pubmed
Glomerulonephritis was induced in
rats by intravenously injecting HSV at 3 mg / kg . -
pubmed
[ Assessment of multimodal effect of
cytoflavin in the
acute brain stroke in
patients with
metabolic syndrome ] . -
pubmed
A phase III trial of TTFields monotherapy compared to active chemotherapy in recurrent
glioblastoma patients established that TTFields therapy is associated with minimal toxicity , better quality of life , and comparable efficacy to chemotherapy . -
pubmed
RESULTS : Seven
patients had operations due to late - presenting
CHD in our institution over 30 years . -
pubmed
There was no
recurrence in any of the
patients on follow - up . -
pubmed
We found that compared to wild - type
mice , bacterial colony forming units 48 h after intranasal
infection with
K. - pubmed
Acquired absolute vitamin K deficiency in a
patient undergoing
warfarin therapy . -
pubmed
A 78 - year - old
woman was admitted to our hospital because of
dyspnea and
sore throat diagnosed as
pharyngitis 1 week before admission . -
pubmed
Since the
coagulopathy responded to intravenous
VK administration , the
patient was clinically diagnosed with
warfarin - related relative
VKD . -
pubmed
Severe
coagulopathy in
patients undergoing
warfarin therapy is primarily caused by , relative
VKD . -
pubmed
Human postural control , which relies on information from vestibular , visual , and proprioceptive inputs , degrades with aging , and falls are the leading cause of
injury in older adults . -
pubmed
Deglutition - Induced Real - Time Directional Displacements in
Head - and - Neck Cancer Patients --- Dynamic Volume Shuttle Imaging Analysis . -
pubmed
METHODS : Thirty - six adult male
Wistar rats , were randomly assigned to groups of normal control ( n = 6 ; no manipulation ) and
liver fibrosis ( n = 30 ; given a subcutaneous injection of 40 % chronic
carbon tetrachloride (
CCl4 ) ) . -
pubmed
Ebola causes highly lethal
hemorrhagic fever in
humans with no licensed countermeasures . -
pubmed
The respiratory tree tissue of the
sea cucumber is an excellent material for studying aestivation , undergoing obvious
atrophy during aestivation . -
pubmed
PATIENTS AND METHODS : Seventeen eyes of 15 consecutive
patients diagnosed with
PCV based on typical clinical and angiographic findings were imaged with macular SD - OCT including line scans passing through the
polyps . -
pubmed
PURPOSE OF REVIEW : This study focuses on the epidemiology and management of
mucormycosis in hematopoietic stem cell transplant
patients , a life - threatening mold
infection whose incidence has increased over the past decades . -
pubmed
RECENT FINDINGS :
Mucormycosis may occur in hematopoietic stem cell transplant
recipients with severe
graft - versus - host disease ,
steroids ,
neutropenia ,
iron overload ,
diabetes , and
malnutrition , or those who received antifungals not active against Mucorales . -
pubmed
The reversed halo sign on chest computed tomography has been associated to
mucormycosis in
neutropenic patients , but is not pathognomonic . -
pubmed
Attachment , penetration and early host defense mechanisms during the
infection of filamentous brown algae by
Eurychasma dicksonii . -
pubmed
BACKGROUND :
Patients with symptoms that impersonate a
stroke but are later found to have an alternate diagnosis are termed
stroke mimics . -
pubmed
Stroke mimics are described and compared with acute
ischemic stroke patients for demographics , clinical characteristics , and
bleeding complications . -
pubmed
RESULTS : We identified 38
stroke mimic ( 12 % ) and 285
ischemic stroke ( 88 % ) t - PA - treated
patients . -
pubmed
Compared with
ischemic stroke patients , mimic
patients were younger , more often female , and reported a history of
stroke more often . -
pubmed
There were no
intracerebral hemorrhages or
deaths in the mimic
patients but there were 2 systemic
hemorrhages ( 5.2 % ) . -
pubmed
METHODS : A single - blind , two - parallel group , randomized trial was conducted at three medical centers ( Guangzhou , China ) , including
patients with both biopsy - confirmed
hepatocellular carcinoma and lung
metastasis . -
pubmed
METHODS : From October 2005 to August 2013 , we performed LATG with lymph - node dissection and Roux - en - Y reconstruction using the overlap method in 77
patients with
gastric cancer . -
pubmed
There were no
deaths , and morbidity rate was 13 % , including one
patient ( 1 % ) who developed
anastomotic stenosis . -
pubmed
BACKGROUND :
Stroke is a significant complication in
patients supported with continuous - flow left ventricular assist devices ( CF - LVAD ) and
hypertension is a significant risk factor for
stroke , but the association between blood pressure and
stroke in LVAD
patients is not well characterized . -
pubmed
These results identify management of
hypertension as a potential modifiable risk factor for reducing the incidence of
stroke in
patients supported by CF - LVAD . -
pubmed
INTRODUCTION : Nipple - sparing mastectomy has become a contemporary surgical treatment that achieves improved cosmetic outcomes for
patients with
breast cancer in Western countries . -
pubmed
METHODS : Between 2006 and 2011 , 42
patients with
breast cancer who underwent 44 nipple - sparing mastectomy operations with immediate reconstruction at the Tri - Service General Hospital were reviewed . -
pubmed
CONCLUSION : Nipple - sparing mastectomy is a safe procedure in properly selected
patients with
breast cancer . -
pubmed
In addition , we have identified new genetic variants of the Chinese Crested
dog that will contribute to further whole - genome sequencing studies aimed to identify mutations associated with
monogenic diseases with autosomal recessive inheritance . -
pubmed
Intracranial application of near - infrared light in a hemi -
parkinsonian rat model : the impact on behavior and cell survival . -
pubmed
OBJECT The authors of this study used a newly developed intracranial optical fiber device to deliver near - infrared light ( NIr ) to the midbrain of
6 - hydroxydopamine (
6 - OHDA)-lesioned
rats , a model of
Parkinson ' s disease . -
pubmed
It exhibits efficacious anti -
ischemic and anti -
atherosclerosis activities in
rats . -
pubmed
A fecal metabolomics based on Liquid Chromatography - Mass Spectrometry combined with clinical histopathology and blood lipid estimation was employed to assess the efficacy and the metabolic changes caused by administration of
DBZ in
atherosclerotic rats . -
pubmed
Nevertheless ,
atherosclerotic rats administered both
DBZ ( at a dose of 40 mg kg(-1 ) ) and
simvastatin ( at a dose of 20 mg kg(-1 ) ) showed good therapeutic effects . -
pubmed
The results of the metabolomics studies showed that 55 differential metabolites such as
sebacic acid ,
enterodiol ,
nonanedioic acid ,
dodecanedioic acid ,
cholic acid ,
13 ( S )- HPODE ,
deoxycholic acid , some
phosphatidylglycerol and
phosphatidic acids were found , indicating that abnormal metabolism occurred in the pathways of
fatty acid oxidation ,
linoleic acid metabolism ,
bile acid biosynthesis and
glycerophospholipid metabolism in
atherosclerotic rats . -
pubmed
The 75 - year - old female
patient experienced the
trauma at the age of 4 . -
pubmed
Sixty
human teeth samples were prepared from freshly extracted , unrestored ,
caries free , nonattrited maxillary first premolars . -
pubmed
Children with
LRTI were found to have significantly lower mean
vitamin D levels as compared to controls There was likewise a correlation between
vitamin D levels and incidence and severity of
LRTI . -
pubmed
Recovery of a 10 - year - old girl from
methicillin - resistant
Staphylococcus aureus sepsis in response to low - dose
ceftaroline treatment . -
pubmed
Various bacterial species were isolated from
multiple wounds , and
methicillin - resistant
Staphylococcus aureus (
MRSA ) was one among them . -
pubmed
After the amputation of her lower legs , she developed
MRSA sepsis , which was successfully treated with a relatively low dosage of
ceftaroline (
Zinforo ( ) /
Teflaro ( ) ; 2x9 mg / kg / d ) , although the
bacterial isolate 's minimal inhibitory concentration ( 1.5 - 4 mg / L ) suggested a decreased susceptibility . -
pubmed
Determinants of
hypofibrinolysis in
patients with
digestive tract cancer . -
pubmed
Furthermore , studies in
murine models and
humans have identified the bone marrow ( BM ) as a previously neglected site of
diabetic end - organ damage , characterized by
microangiopathy ,
neuropathy ,
fat deposition , and
inflammation . -
pubmed
A better understanding of the molecular and cellular processes that govern the BM stem cell niche , cell mobilization , and kinetics in peripheral tissues may uncover new therapeutic strategies for
patients with
diabetes . -
pubmed
Patients with
RE also exhibited significant declines in esophageal mucin secretion ; however , after healing of
RE with
rabeprazole , this rate increased significantly . -
pubmed
The purpose of this study is to longitudinally characterize MRI features after LITT in
patients with
drug - resistant epilepsy , primarily in the setting of
mesial temporal sclerosis . -
pubmed
Previous studies have demonstrated that
oridonin , a
tetracyclic diterpenoid compound extracted from
Rabdosia rubescens , inhibits proliferation and induces apoptosis in several
tumor cell lines . -
pubmed
PARTICIPANTS : A total of 100
adolescents , between the ages of 12 and 18 years , who sustained
concussion due to sports . -
pubmed
RESULTS : Twenty - four
patients ( 24 % ) were prescribed medications in this study , all of whom reported
headache at the time of medication prescription . -
pubmed
It remains the drug of choice for the treatment of serious
infections caused by
methicillin - resistant
Staphylococcus aureus . -
pubmed
Only three of the eight
patients received nephrotoxins prior to development of
nephrotoxicity . -
pubmed
METHODS : This was a retrospective cohort study of severe
sepsis patients admitted to the hospital from the ED between January 2005 and February 2010 . -
pubmed
Mammalian milk allergy : case presentation and review of prevalence , diagnosis , and treatment . -
pubmed
We simultaneously modelled all
fimasartan plasma concentrations and 24 - h ambulatory blood pressure monitoring ( ABPM ) data from 39
patients with essential
hypertension and 56 healthy
volunteers . -
pubmed
Topical evening primrose oil as a possible therapeutic alternative in
children with
molluscum contagiosum . -
pubmed
Resveratrol improved
detrusor fibrosis induced by mast cells during progression of
chronic prostatitis in
rats . -
pubmed
After
rat model of
CP is established by subcutaneously injecting
DPT vaccine ,
rats are treated with
resveratrol . -
pubmed
Circulating
influenza viruses evade neutralization in their
human hosts by acquiring escape mutations at epitopes of prevalent antibodies . -
pubmed
CONCLUSIONS : UAS is highly effective for
OSA treatment in selected
patients with an
apnea -
hypopnea index between 15 and 65 events per hour and higher
body mass index . -
pubmed
OBJECTIVES : To describe a cohort of classic
Kaposi sarcoma in a low - endemic area for
KSHV , to highlight the features of
CKS in MSM and identify prognostic factors . -
pubmed
METHODS : A total of 42
VKH patients ( 84 eyes ) and 45 normal controls ( 90 eyes ) were included in this study . -
pubmed
All of the
patients showed active
uveitis and were referred to us within 2 months after disease onset . -
pubmed
RESULTS : All investigated
VKH patients showed a significantly
decreased visual acuity and retinal structural changes before treatment . -
pubmed
Dielectric and thermodynamic study of Hb exploring
Moringa Oleifera leaves extract potential against
radiation damage . -
pubmed
18F - FDG uptake in enlarged lymph nodes is always suspicious , especially in
cancer patients . -
pubmed
We report a case of
hypermetabolic internal mammary lymphadenopathy in a
breast cancer patient who was previously treated with bilateral mastectomy and implants . -
pubmed
Vigilant PET interpretation is required in
breast cancer patients who have evidence of
breast implant rupture . -
pubmed
Clinical features and corneal optical anisotropies in a
rabbit model of
limbal stem cell deficiency . -
pubmed
PURPOSES : To investigate the intra - laboratory reproducibility of clinical features and to evaluate corneal optical anisotropies in a
rabbit model of
limbal stem cell deficiency . -
pubmed
METHODS :
Limbal injury was induced in the right eye of 23 adult New Zealand White
rabbits using a highly aggressive protocol that combined 360 degrees limbal peritomy , keratolimbectomy , alkaline
chemical burn , and mechanical removal of the epithelium . -
pubmed
CONCLUSIONS : These results suggest that
rabbit models of
limbal stem cell deficiency must be rigorously screened for use in preclinical studies to ensure experimental homogeneity because protocols used to create
limbal stem cell deficiency could be not associated with good intra - laboratory reproducibility of clinical features . -
pubmed
Partial findings released from that study showed significantly increased incidences and/or trends for
gliomas and
glial cell hyperplasias in the brain and
schwannomas and
Schwann cell hyperplasias in the heart of exposed male
rats . -
pubmed
These results , as well as the findings of significantly increased DNA damage ( strand breaks ) in the brains of exposed
rats and
mice , reduced pup
birth weights when pregnant dams were exposed to
GSM- or
CDMA - modulated RFR , and the induction of
cardiomyopathy of the right ventricle in male and female
rats clearly demonstrate that the null hypothesis has been disproved . -
pubmed
The NTP findings are most important because the International Agency for Research on
Cancer ( IARC ) classified RFR as a " possible
human carcinogen " based largely on increased risks of
gliomas and
acoustic neuromas ( which are
Schwann cell tumors on the acoustic nerve ) among long term users of cell phones . -
pubmed
In contrast to those criticisms , an expert peer - review panel recently concluded that the NTP studies were well designed , and that the results demonstrated that both GSM- and
CDMA - modulated RFR were carcinogenic to the heart (
schwannomas ) and brain (
gliomas ) of male
rats . -
pubmed
The best growth of
strain FW-11 T occurred at 30 C and pH 6.0 - 7.0 . -
pubmed
The average nucleotide identity relatedness values between
strain FW-11 T and the two type
strains (
S. - pubmed
We did a prospective study and included all
patients with
acute flaccid weakness and documented serum
potassium of & lt;3.5 mEq / L during the period between January 2009 and August 2015 . -
pubmed
We studied the incidence , etiology , clinical profile , and acid - base disturbances in
patients presenting with
hypokalemic paralysis and analyzed the significance of periodic and non - periodic forms of
hypokalemic paralysis on
patient 's outcome . -
pubmed
Eighty - one ( 39 % )
patients had
metabolic acidosis , 78 ( 38 % ) had normal acid - base status , and 47 ( 23 % ) patients had
metabolic alkalosis . -
pubmed
Patients with non - periodic
paralysis had more
urinary loss ( 40.1 vs. 12.2 mmol , P = 0.04 ) , more requirement of
potassium replacement ( 120 vs. 48 mmol , P = 0.05 ) , and longer recovery time of
weakness ( 48.1 vs. 16.5 h , P = 0.05 ) than
patients with periodic
paralysis . -
pubmed
Patients with periodic
paralysis had significant incidence of rebound
hyperkalemia . -
pubmed
Propranolol eye drops in
patients with
corneal neovascularization . -
pubmed
RATIONALE : Studies performed in
animal models of
corneal neovascularization suggested the possible efficacy of a treatment with
propranolol . -
pubmed
PATIENT CONCERNS : Two
patients with
corneal neovascularization complicating the
Stevens - Johnson syndrome , not responsive to
steroids and
cyclosporine , were treated with
propranolol eye drops . -
pubmed
OUTCOMES : Both
patients reported dramatic subjective benefits ( reduction of
photophobia and discomfort ) without adverse effects , and in the
patient with a less advanced disease , an objective reduction of neovascularization and an improved visual acuity was observed . -
pubmed
Loss of skeletal muscle mass and its predictors in
type 2 diabetes patients under a multifaceted treatment approach . -
pubmed
Methods : For 6 months we observed the changes in the body compositions of 72 Japanese
patients with
type 2 diabetes who underwent multifaceted treatment including educational hospitalization . -
pubmed
Conclusions : Baseline accumulation of visceral fat may predict a preferential reduction of visceral fat rather than skeletal muscle during weight control programs in
type 2 diabetes patients . -
pubmed
Animal models of radiation
retinopathy could provide means to identify effective therapies . -
pubmed
Here , we review the literature for all
animal models of radiation
retinopathy , summarize anatomical highlights pertaining to
animal models , identify additional physiological factors to consider when investigating
radiation retinopathy , and explore the use of clinically relevant tests for studying in vivo models of radiation
retinopathy . -
pubmed
Testing for
EBV is an investigation required at baseline in
acute hepatitis and physicians should carefully evaluate serological results , including those for viral and
autoimmune hepatitis that may be falsely positive in
infectious mononucleosis . -
pubmed
Previous studies in
humans have indicated that de novo lipogenesis contributes considerably to redundant lipid storage and
steatosis in the liver of
patients with
nonalcoholic fatty liver disease (
NAFLD ) , and then more severe complications occur . -
pubmed
However , the molecular mechanism by which EA attenuates
hepatic steatosis in
individuals with undesirable hepatic genetic alterations remains rarely studied . -
pubmed
Human hepatoma cell lines were used for mechanical validation in vitro . -
pubmed
MATERIALS AND METHODS : Thirty - seven
children with
Hodgkin lymphoma underwent 1.5 - tesla ( T ) whole - body MRI using short tau inversion recovery ( STIR ) half - Fourier - acquisition single - shot turbo - spin - echo and diffusion - weighted imaging ( DWI ) . -
pubmed
Patients with
end - stage renal disease (
ESRD ) whether on dialysis therapy ( DTDT ) or received a kidney transplant ( KT ) have previously shown unfavorable surgical outcomes . -
pubmed
WES has the potential to provide a rapid and more accurate genetic diagnosis in
ARA , which is crucial for the treatment of the
patients . -
pubmed
Transcriptome and physiology analysis identify key metabolic changes in the liver of the large
yellow croaker (
Larimichthys crocea ) in response to acute
hypoxia . -
pubmed
However ,
hypoxia stress become a major obstacle to the benign development of
L. - pubmed
To understand the energy metabolism mechanism adapted to
hypoxia , we analyzed the transcriptome and physiology of
L. - pubmed
This study increases our understanding of the energy metabolism mechanism of the
hypoxia response in fish and provides a useful resource for
L. - pubmed
Infection caused by
Borrelia burgdorferi can occur throughout Poland and therefore , according to ECDC description , the whole country should be considered as an endemic area . -
pubmed
About 60 % of
patients with multiple
warts showed complete clearance of distant untreated
warts . -
pubmed
Vascular aging is an important physiological and pathological basis for the aging of organs and systems of the
human body and is the common pathogenesis of various
chronic diseases in the elderly . -
pubmed
Importance
Chlamydia trachomatis is an obligate intracellular pathogen , causing
sexually transmitted diseases and
trachoma . -
pubmed
Maxillary constriction is a common skeletal
craniofacial abnormality , and
transverse maxillary deficiency affects 30 % of
patients receiving orthodontic and surgical treatment . -
pubmed
The study group consisted of 36
patients ( 16
women ) aged 17 to 42 years ( M = 27.1 ; SD = 7.8 ) with a known complete
skeletal crossbite and who underwent transpalatal distraction procedure . -
pubmed
( 2)Univariate analysis showed that
patients with grade III - IV
acute graft - versus - host disease (
aGVHD ) or hematopoietic cell transplantation comorbidity index ( HCT - CI ) > = 2 points or
patients in very high - risk group of the Revised International Prognostic Scoring System ( IPSS - R ) had significantly decreased OS [ ( 42.9 + -13.2 ) % vs ( 72.9 + -4.2 ) % , chi(2)=8.620 , P=0.003 ; ( 53.3 + -7.6 ) % vs ( 72.6 + -4.7 ) % , chi(2)=6.681 , P=0.010 ; ( 53.8 + -6.8 ) % vs ( 76.6 + -6.2 ) % vs ( 73.3 + -7.7 ) % , chi(2)=6.337 , P=0.042 ] . -
pubmed
Detection of multidrug - resistant
strains of Salmonella in poultry farms suggests the need for detailed epidemiological and molecular studies to establish sources of acquisition of resistant
Salmonella strains . -
pubmed
Optimized Protocol to Generate Spinal Motor Neuron Cells from Induced Pluripotent Stem Cells from
Charcot Marie Tooth Patients . -
pubmed
Although several protocols are available to differentiate hiPSCs into neurons , their efficiency is still poor for
CMT patients . -
pubmed
Thus , our goal was to develop a robust , easy , and reproducible protocol to obtain MNs from
CMT patient hiPSCs . -
pubmed
This method of generating MNs from
CMT patients in vitro shows promise for the further development of assays to understand the pathological mechanisms of
CMT and for drug screening . -
pubmed
PURPOSE : This study aimed to explore the incidence rate of
delirium and to determine the risk factors among
critically ill older
patients . -
pubmed
Streptococcus pneumoniae is one of the leading causes of
death worldwide . -
pubmed
INTRODUCTION : Preclinical data demonstrate the potential for exercise training to protect against
anthracycline - related
cardiotoxicity , but this remains to be shown in
humans . -
pubmed
Korea had been one of hyperendemic countries of
human parasitic infections until 1970s . -
pubmed
Using a humanized lupus
mouse model , we showed that the transfer of Th17 cell - depleted PBMCs from
lupus patients resulted in a significantly reduced plasma cell response and attenuated
renal damage in recipient
mice compared to the transfer of total
SLE PBMCs . -
pubmed
CONCLUSIONS : Although larger studies are needed to confirm these results , our data open up new ways of investigation into the effects of AIs on QoL in HR+
BC patients . -
pubmed
Thus , we report the development of valuable
animal models of
osteopetrosis , and our results shed light on drug development for antiosteopetrosis therapy . -
pubmed
Therefore , in vivo analyses were performed following
ischemia in normal , ischemic , and
AY9944 - treated
animal groups . -
pubmed
Among 23 isolates of
Neisseria meningitidis tested , which included representatives of sero - groups A , B , C , D , X , Y , and Z , only one
strain in group X gave a false - positive reaction . -
pubmed
Bluetongue in
cattle : effects of vector - transmitted
bluetongue virus on calves previously infected in utero . -
pubmed
Three of 7 principal calves , after a challenge of immunity exposure by
bites of
bluetongue ( BT ) virus - infected
Culicoides variipennis , became latently infected with
BT virus . -
pubmed
These calves were born to heifers infected with the homologous virus by
bites of
C variipennis at 60 or 120 days ' gestation . -
pubmed
A study of repeat myelograms carried out in 93
patients revealed that the incidence of
thecal scarring following Conray lumbar radiculography is high ( 61 % of all cases ) , and only slightly lower than that found after Myodil myelography ( 74 % ) . -
pubmed
Patients at risk for other reasons carrying residual stones after cholecystectomy , or suffering from
stenosis of the papilla , or harboring stones in the choledochus after choledochoduodenostomy should be subjected to endoscopic papillotomy . -
pubmed
Patients at risk for other reasons suffering from
cholecystolithiasis or
choledocholithiasis should be subjected at first to endoscopic papillotomy , and only thereafter to cholecystectomy . -
pubmed
Eight male
patients with
cystic fibrosis , normal nutrition , normal physical activity , relatively mild
pulmonary disease , no evidence of
liver disease and no family history of
diabetes mellitus underwent a series of
carbohydrate tolerance tests in comparison with a group of 18 normal male subjects matched for age and
body weight . -
pubmed
Bladder neuropathy and
gastric paralysis in
polyarteritis nodosa associated with
hepatitis B virus . -
pubmed
Inhibition of
aminophylline - induced
convulsions in
mice by antiepileptic drugs and other agents . -
pubmed
)-induced
convulsions in
mice . -
pubmed
Valproate at 500 mg / kg protected fewer than 50 % of
mice against the
clonic phase . -
pubmed
Four treatment regimens for
patients with specified combinations of
low back pain and
sciatica were evaluated . -
pubmed
Traction , for
patients with
low back pain and
sciatica , and epidural injections when a
root palsy was present also produced some significant
pain relief . -
pubmed
The results of these studies suggest that the pathogenesis of tissue invasion and
hemorrhagic tissue necrosis observed in
P. - pubmed
Ten
patients recovered uneventfully and ten developed a major
infection , three of whom died . -
pubmed
[ Severe
pneumopathy caused by
Pneumocystis carinii in
chickenpox in a immunosuppressed adult ] . -
pubmed
This would discard duct obliteration as a procedure suitable for pancreas transplantation , since optimal endocrine pancreas function is the aim of pancreas transplantation in
patients suffering from
type - I diabetes mellitus . -
pubmed
To evaluate the appropriate dosage of
polyestradiol phosphate (
PEP ,
Estradurin ) as single - drug therapy ,
patients with metastatic
prostatic carcinoma were given 80 , 160 or 240 mg
PEP every 4 weeks for at least 6 months . -
pubmed
We evaluated the pulmonary status of 18
children 7 to 8 years after their hospitalization for
chlamydial pneumonia of infancy . -
pubmed
Effects of
muramyl dipeptide and
trehalose dimycolate on resistance of
mice to
Toxoplasma gondii and
Acanthamoeba culbertsoni infections . -
pubmed
The effects of synthetic
muramyl dipeptide (
MDP ) and natural
trehalose dimycolate (
TDM ) against
parasitic infections by intracellular
Toxoplasma gondii and free - living
Acanthamoeba culbertsoni were studied . -
pubmed
Partial protection against lethal
intranasal A. culbertsoni infection was conferred by specific immunization with viable trophozoites of nonpathogenic
Acanthamoeba lugdunensis . -
pubmed
Wild - type Gross leukemia virus and heritable
autoimmune disease of
New Zealand mice . -
pubmed
This report provides a background to biochemical investigations on
human glycerol kinase deficiency , an
inborn error of metabolism which may be characterized by
adrenal hypoplasia and insufficiency . -
pubmed
Subjects were 50
patients fulfilling DSM - III criteria for
schizophrenic disorder who had been successfully maintained with 25 mg or less of
fluphenazine decanoate . -
pubmed
We present the clinical case of a female
patient with
cirrhosis of the liver . -
pubmed
The benefits in
patient management are discussed and particular note is made of this technique for female patients with chronic
urinary retention and
overflow incontinence . -
pubmed
Computed tomography of the pulmonary hilum in
patients with
bronchogenic carcinoma . -
pubmed
In 30
patients with histologically proven
bronchogenic carcinoma , computed tomographic ( CT ) scans of the pulmonary hila , plain radiographs , and medical records were reviewed . -
pubmed
The frequencies of recovered disomy among the meiotic segregants of
yeast (
Saccharomyces cerevisiae )
triploids were assessed under conditions in which all 17
yeast chromosomes were monitored simultaneously . -
pubmed
Ten
hypertensive ( hyper ) and
hypotensive ( hypo )
turkeys of both sexes were used to evaluate the effect of various stimuli on blood pressure ( BP ) and heart rate ( HR ) . -
pubmed
The effects of various doses and the time of injection have been measured quantitatively in four transplantable
rodent tumours . -
pubmed
Neonatal
rats were subjected to transient
cerebral hypoxic - ischemia ( unilateral occlusion of the common carotid artery + 7.70 %
O2 for 100 min ) and allowed to recover for 3 h , 24 h , 2 days or 14 days . -
pubmed
METHODS : We studied 30 subjectively asymptomatic
patients aged 8 to 25 years treated for pediatric
malignancies with chest irradiation ( XRT ) + /- chemotherapy . -
pubmed
METHODS : A retrospective , computer - aided search identified 442 consecutively registered
patients with
malignant melanoma at the Cutaneous Oncology Program . -
pubmed
All
patients had stage 1 or 2 disease (
cutaneous disease only ) at diagnosis . -
pubmed
We describe a young woman with a concomitant
infection of
C. - pubmed
From 1973 to 1991 , 13
patients [ 4
females ( 30 % ) and 9 males ( 70 % ) ] were diagnosed with
adrenal carcinoma at our hospital . -
pubmed
Eleven
patients ( 85 % ) presented with
abdominal symptoms and 8 ( 61 % ) with
paraneoplastic syndrome . -
pubmed
On follow - up , 10
thrombotic episodes occurred in 10
patients , 8 of whom were receiving anticoagulant therapy . -
pubmed
Derivative ( 11)t(7;11)(q11;q24 ) in a
child with
acute megakaryoblastic leukemia . -
pubmed
We document the clinical , morphologic , and cytogenetic findings in a 2 1/2 - year - old
patient with
acute megakaryoblastic leukemia . -
pubmed
CONCLUSIONS : The results further high - light the differences between
patients with primary progressive and those with relapsing remitting / secondary progressive
multiple sclerosis . -
pubmed
Overall survival was lower for
patients with glandular
carcinomas than for those with
squamous cell carcinomas ( 26 % vs. 55 % , P = 0.09 ) . -
pubmed
This difference was almost entirely due to increased mortality in
patients with Stage Ib
adenocarcinomas ( 53 % vs. 88 % for
squamous cell carcinoma , Stage Ib , P = 0.03 ) . -
pubmed
CONCLUSIONS : The major prognostic markers for
cervical cancer survival in this high risk
patient population were clinical stage and histology , factors identical to those identified for other populations . -
pubmed
The present study was performed to determine the site of aromatization in
human breast cancers , using both immunocytochemistry and in situ hybridization . -
pubmed
The efficacy of single - dose
aprotinin 2 million KIU in reducing
blood loss and its impact on the incidence of
deep venous thrombosis in
patients undergoing total hip replacement surgery . -
pubmed
STUDY OBJECTIVE : To evaluate the efficacy of a 2 million KIU single dose of
aprotinin on blood loss , transfusion requirements , and incidence of
deep venous thrombosis (
DVT ) in
patients undergoing total hip replacement surgery . -
pubmed
On the seventh postoperative day , all
patients in both groups underwent venography to ascertain the incidence of
DVT . -
pubmed
Infection of erythrocytes with mature asexual stages of
P. - pubmed
[ Proliferation of T - cells , macrophages , neutrophilic granulocytes and fibroblast - like cells in the synovial membrane of
patients with
rheumatoid arthritis ] . -
pubmed
Neurologic findings in coronary artery bypass
patients : perioperative or preexisting ? -
pubmed
OBJECTIVES / DESIGN : This prospective study compares the incidence of preexisting
neurologic findings in elective cardiac surgery
patients presenting with and without
coronary atherosclerosis . -
pubmed
MEASUREMENTS AND MAIN RESULTS : The
patients , 9 of 24 of whom were female , were aged 46 to 78 years and , other than
ischemic heart disease , had medical histories that were similar between groups , with the exception of one
patient having
scleroderma . -
pubmed
Nine percent ( 1 of 11 ) of the valve - only
patients showed subtle preoperative
neurologic abnormalities , compared with 89 % ( eight of nine ) of the valve
patients having concomitant coronary surgery and 100 % ( four of four ) of coronary artery bypass - only
patients . -
pubmed
CONCLUSION : This survey shows that both subtle
neurological abnormalities and magnetic resonance imaging lesions can be found in a high percentage of
patients with
coronary atherosclerosis . -
pubmed
Malignant colonic neoplasia in
cats : 46 cases ( 1990 - 1996 ) . -
pubmed
OBJECTIVE : To evaluate a group of
cats with malignant
colonic neoplasia and to identify factors related to survival time . -
pubmed
ANIMALS : 46
cats with malignant
colonic neoplasia . -
pubmed
A diagnosis of malignant colonic
neoplasia had been established by histologic examination of endoscopic biopsy specimens ( 3
cats ) , biopsy specimens obtained during laparotomy ( 38 ) , or necropsy specimens ( 5 ) . -
pubmed
Histopathologic diagnoses included
adenocarcinoma ( 21
cats ) ,
lymphoma ( 19 ) ,
mast cell tumor ( 4 ) , and
neuroendocrine carcinoma ( 2 ) . -
pubmed
CLINICAL IMPLICATIONS : Obtaining clean margins at surgery seems to increase survival time in
cats with malignant
colonic neoplasia . -
pubmed
Data from this study indicate that the survival time of certain
cats with
colonic lymphoma may not be affected by chemotherapy . -
pubmed
Cats with colonic
adenocarcinoma should receive a subtotal colectomy with consideration of
doxorubicin administration to increase survival time . -
pubmed
Clinical efficacy of
lactulose in
cirrhotic patients with and without subclinical
hepatic encephalopathy . -
pubmed
Seventy - five cirrhotic
patients with
hyperammonemia in the past or at the time of the study were randomly divided into two groups ( treated with
lactulose or nontreated ) in 14 hospitals in Japan . -
pubmed
Thirty - six cirrhotic
patients were diagnosed as having subclinical
hepatic encephalopathy (
SHE ) , and 39 were diagnosed as non - SHE . -
pubmed
We concluded that
lactulose treatment in
cirrhotic patients with
SHE is effective with respect to psychometric tests . -
pubmed
The drugs undergo extensive hepatic metabolism ; dosage adjustments should be considered for
patients with
hepatic dysfunction . -
pubmed
To elucidate the conditions of
atrophy in the sternocleidomastoid muscle ( SCM ) after modified neck dissection ( MND ) , we tried to scrutinize the atrophic regions in the SCM and determine the cause of
atrophy , by electromyography in 40
patients with SCM
atrophy following
MND . -
pubmed
Atrophy was observed in the caudal portion in the SCM in 90 % of the
patients . -
pubmed
Electromyographic examination revealed
neurogenic atrophy in 24
patients ,
ischemic atrophy in 11 , and a mixing of both types in 5 . -
pubmed
BACKGROUND AND PURPOSE : We sought to determine the incidence of recurrent
carotid stenosis in
patients in the Asymptomatic Carotid Atherosclerosis Study ( ACAS ) who had undergone carotid endarterectomy and were prospectively followed with Doppler ultrasound for up to 5 years . -
pubmed
Of the 136
patients judged to have recurrent
stenosis , only 8 ( 5.9 % ) underwent reoperation ( only 1 for symptoms ) . -
pubmed
cereus strains in concentrated whey were 100 % similar to the type
strain in 16S rDNA sequence ( 500 bp ) although they were not or only poorly recognized as
B. - pubmed
When studies identifying
patients with
fracture , rather than numbers of
fractures were pooled , the magnitude of effect was less ( RR 0.74 ; 95 % CI 0.60 - 0.93 ) , and the separate effects on
vertebral and non - vertebral fractures was of borderline significance . -
pubmed
PURPOSE : To evaluate the role of computed tomography in
patients with
dacryostenosis . -
pubmed
OBJECTIVES : To compare the ultrasonographic ( US ) appearances of the oral mucosa in health with
patients with
systemic sclerosis (
SSc ) . -
pubmed
METHODS : An innovative 20 MHz US scanner was used to examine the lips , cheeks and oral vestibule of ten healthy
persons and ten
patients with
SSc . -
pubmed
The clinical , US and histopathological features of one
patient with a
fibro - epithelial polyp of the buccal mucosa are reported in detail . -
pubmed
RESULTS : Two
patients with
SSc displayed increased echogenicity due to fibrotic deposits . -
pubmed
Staphylococcus aureus pneumonia ,
hyponatremia ,
hypertension ,
proteinuria , and
hematuria in a 14 - year - old boy . -
pubmed
PARTICIPANTS : Five refractive
surgeons and 29,916 eyes that underwent surgical correction of
ametropia ( 83.2 % were
myopic ) ranging from -0.75 to -29.00 diopters ( D ; mean : -6.19 D ) and from +1.00 to +6.00 D ( mean : +3.23 D ) participated in this retrospective study . -
pubmed
It is very important to inform
patients that LASIK only corrects the refractive aspect of
myopia . -
pubmed
We employed three
strains of
H. - pubmed
The progression of
muscular weakness of
patients suffering from
muscular dystrophies directly correlates with the progressive loss of myofibers , accompanied by
fibrosis . -
pubmed
No systematic data are available for
patients with different
kidney diseases . -
pubmed
We report the case of a
patient with a
pseudoaneurysm of the ascending aortic clinically diagnosed 5 months after surgical replacement of the aortic valve . -
pubmed
METHODS : Forty - six
patients suspected of having
moyamoya disease were examined with high - resolution turbo MR angiography with the ZFI technique , MRI , and conventional angiography . -
pubmed
Moyamoya disease was diagnosed in 42 of these
patients . -
pubmed
Fifteen
patients had persistent
AF ( & gt ; or = 6 months ) , and the remaining 15
patients had no history of
AF . -
pubmed
Idiotype - based immunotherapy has been explored in
myeloma patients with disappointing results . -
pubmed
The importance of routine screening for
microalbuminuria in
patients with
diabetes has gained widespread acceptance . -
pubmed
A
patient undergoing excision of
phaeochromocytoma developed refractory
hypotension which was complicated by significant intraoperative
blood loss . -
pubmed
All three studies demonstrated a significant survival benefit for
bladder cancer patients receiving adjuvant combination therapy . -
pubmed
OBJECTIVES : To present the unique case of a
patient who sustained an ipsilateral and contralateral
injury after external
laryngeal trauma . -
pubmed
METHODS : A case report is presented of a
patient who sustained both an ipsilateral and a contralateral
injury after blunt
laryngeal trauma . -
pubmed
METHODS : Normal
Sprague - Dawley rats rendered
diabetic by a single injection of
streptozotocin ( 50 mg / kg ) were treated with either
aminoguanidine ,
ramipril or standard
water . -
pubmed
A diagnosis of
syndrome of inappropriate secretion of antidiuretic hormone (
SIADH ) was mentioned in eight
patients , sometimes without checking their urinary
electrolytes or osmolality . -
pubmed
RESULTS : No perioperative mortality was seen , and 5 % of the
patients had minor
infections of the wound , not resulting in loss of the bypass , the limb , or life . -
pubmed
We analyzed gene expression in various
rat conditions to identify novel candidate genes for
schizophrenia . -
pubmed
METHODS : A clinical sequential trial was designed and the biosynthetic bone and the
patient 's ilium were respectively used in the treatment of
femoral nonunions and interbody fusion . -
pubmed
[ Collective dietary toxi -
infection by means of
Salmonella of probable South - American origin (
Salmonella bredeney ) ] . -
pubmed
Blood pressure ,
cholesterol content of serum and tissues and
atherogenesis in the
rat . -
pubmed
Rats with high serum
lipide concentrations developed
intimal lesions similar to those of
human atherosclerosis . -
pubmed
On the other hand ,
rats receiving
desoxycorticosterone acetate without salt or salt without
desoxycorticosterone acetate did not show any intensification of
hypercholesterolemia or
hyperlipemia . -
pubmed
It remained uncertain whether the increase in
atherosclerosis in the
hypertensive animals was dependent on the increased
lipide content of serum and tissues or on a local effect of the elevated blood pressure . -
pubmed
RESULTS : Six out of 11
patients with unilateral positive biopsy specimens were diagnosed as unilateral
cancer , and 9 of 10
patients with bilateral positive biopsy specimens were diagnosed as bilateral
cancer on MRI . -
pubmed
A nested PCR technique was performed to detect a specific 483 bp DNA fragment of
Orientia tsutsugamushi , the aetiological agent of
scrub typhus , in 53 blood samples from 36 patients with acute
pyrexia of unknown origin in southern Thailand . -
pubmed
The specific primers could amplify the specific DNA from all 10 prototype
strains of
O. - pubmed
Thus , nested PCR may be more sensitive than the serological test for diagnosis of
scrub typhus and prolonged persistence of
O. - pubmed
According to examination of 97
patients with
vascular vertigo the dependence on
vertigo to
vertebral spondylosis and insufficiency vertebro - basilar artery was showed . -
pubmed
Vertebral degeneration was noticed in 70.1 % ,
basilar artery insufficiency in 42.3 % of the
patients . -
pubmed
Rotary test showed
labyrinth asymmetry in 41.2 % and in caloric test 50.5 % of the
patients . -
pubmed
Rio Meta
strain of
Plasmodium vivax in
New World monkeys and anopheline mosquitoes . -
pubmed
An archived
strain of
Plasmodium vivax , isolated from Rio Meta , northern Colombia , in 1972 was adapted to grow in splenectomized
Aotus lemurinus griseimembra and
A. - pubmed
Effect of
gemfibrozil on change in renal function in
men with moderate
chronic renal insufficiency and
coronary disease . -
pubmed
We conducted this study to determine whether
gemfibrozil reduced rates of renal function loss in
people with moderate
CRI . -
pubmed
METHOD : 350 opiate - dependent
patients were examined at yearly follow - ups over 4 years using the EuropASI for the assessment of drug - related problems and the CIDI for diagnostic of
psychiatric disorders . -
pubmed
The paper presents a case of 64 years old
man with
infective endocarditis of the mitral valve , complicated with a development of
mycotic aneurysm of the right coronary artery , who was successfully surgically treated . -
pubmed
We report that genetic elimination of mature T and B lymphocytes in a
transgenic mouse model of
inflammation - associated de novo epithelial
carcinogenesis , e.g. -
pubmed
,
K14 - HPV16 mice , limits neoplastic progression to development of
epithelial hyperplasias that fail to recruit innate immune cells . -
pubmed
Adoptive transfer of B lymphocytes or serum from
HPV16 mice into T and B cell - deficient /
HPV16 mice restores innate immune cell infiltration into premalignant tissue and reinstates necessary parameters for full
malignancy , e.g. -
pubmed
Mitochondrial behaviour in the early stages of ROS stress leading to cell
death in
Arabidopsis thaliana . -
pubmed
RESULTS : 193
ESSCLC patients were identified . -
pubmed
However in a double - blind , randomized , placebo - controlled trial with more carefully selected
patients , there was no significant difference between
recurrence rates with 650 or 1300 mg
MgO daily and the placebo . -
pubmed
The failure of
MgO and
Mg ( OH ) 2 as sole therapy may be related to poor absorption and low rates of
Mg deficiency in the
patient populations tested . -
pubmed
CONCLUSIONS : Clinical trial evidence does not justify the use of
MgO or
Mg ( OH ) 2 as a sole therapy for
calcium oxalate kidney stones in a general
patient population . -
pubmed
Clinical trials should focus on
patients who are likely to be
Mg deficient . -
pubmed
Human pulmonary dirofilariasis : a case report and review of the recent Japanese literature . -
pubmed
Human pulmonary dirofilariasis is a rare
zoonotic infection caused by the
dog heartworm
Dirofilaria immitis , which is transmitted via a vector / intermediate host , generally the mosquito . -
pubmed
The authors present a case of histologically diagnosed
human pulmonary dirofilariasis , in which the lesion was resected using video - assisted thoracic surgery ( VATS ) . -
pubmed
Of these 24 patients with
human pulmonary dirofilariasis , 12 ( 50 % ) were men ( mean age 54 years , range 29 - 80 years ) and 67 % were asymptomatic . -
pubmed
OBJECTIVE : To compare the effects of daily ingestion of soy flour ( S ) , ground flaxseed ( F ) , or
wheat flour ( W ) muffins , on quality of life and
hot flash frequency and severity in postmenopausal
women . -
pubmed
I. Cytotoxic cells with specificity for
mouse Moloney
leukemia cells . -
pubmed
Molecular characterization of
human adenomyosis . -
pubmed
METHODS : Forty
Wistar rats were randomly assigned to a control group and an
asthma group ( 20 in each group ) . -
pubmed
There have been no treatment advances for
alcoholic liver disease but , on balance ,
steroids are still favored for carefully selected
patients with
alcoholic hepatitis . -
pubmed
After having established the
mice model of
hypnosis and analgesia by intraperitoneally injecting ( i.p . ) -
pubmed
Heparin and
low molecular weight heparin ( LMWH ) are widely used for treatment of
cancer patients with
thrombosis , a common complication of
malignant disease . -
pubmed
Several recent prospective clinical studies indicate that
heparin might improve outcomes of
human cancer . -
pubmed
Meanwhile , experimental evidence from
mouse models consistently demonstrates that
heparin efficiently inhibits
metastasis . -
pubmed
The use of clinically acceptable amounts of
heparin did not further aff5ct
metastasis rates in such
mice . -
pubmed
Energy homeostasis in
mammals is achieved through tight regulation of tissue - specific metabolic pathways that become dysregulated in
metabolic diseases including
diabetes and
obesity . -
pubmed
The actual knowledge of
HNE reactivity , metabolism , signaling and modulatory effect in the various
human organs should provide a solid background to the investigation of the
aldehyde 's contribution to the pathogenesis of
human major
chronic diseases and would likely promote advanced and oriented applications not only in diagnosis and prevention but also in molecular treatment of
human diseases . -
pubmed
We have treated 30
POEMS patients with ASCT at Mayo Clinic , Rochester . -
pubmed
During transplant period ,
patients had high rates of
fever ,
diarrhea ,
weight gain and
rash ( 93 % , 77 % , 53 % and 43 % , respectively ) . -
pubmed
Depending on the definition used , approximately 50 % of
patients satisfied criteria for
engraftment syndrome . -
pubmed
Patients and methods Seven
patients were treated neurosurgically with laminectomy and
abscess drainage for
spinal epidural abscesses from 1991 to 1994 . -
pubmed
Results All but one
patient had several weeks of local
spinal pain ( mainly after minor
trauma ) , immunosuppression , and all exhibited excessively high blood sedimentation rates . -
pubmed
Since preoperative
neuronal damage persisted too long , only 3
patients showed slight improvement of their neurological functions postoperatively . -
pubmed
We reviewed 40 Corin Cormet 2000 ( Corin , Cirencester , UK ) metal - on - metal resurfacing hips , in 36
patients , for the presence of
femoral neck narrowing . -
pubmed
UNLABELLED : We report diagnostic difficulties in the
patient with
fever of unknown origin . -
pubmed
[
Chronic dizziness in elderly
people : its clinical characteristics and magneto - encephalographic findings ] . -
pubmed
During the last several years , we performed cerebral functional studies using auditory - evoked magneto - encephalography ( MEG ) in elderly
people with chronic
dizziness . -
pubmed
This abnormality is similar to that detected by non - evoked MEG in
temporal lobe epilepsy patients . -
pubmed
In
patients with
Type A abnormality , administration of anticonvulsants brought about dramatic improvement of
dizziness in association with disappearance of rotational abnormalities . -
pubmed
Patients with
Type B abnormality commonly have the asymmetry of body , such as left - right imbalance of visual acuity ,
left - right neck pain , or remarkable
scoliosis , in association with
insomnia and/or
depressive state . -
pubmed
In
patients with
Type A abnormality ,
dizziness may be caused by abnormal neuronal excitements in left or right HPR center . -
pubmed
Pubo - urethral ligament injury causes long - term
stress urinary incontinence in female
rats : an
animal model of the integral theory . -
pubmed
No difference was noted when comparing pubo - urethral ligament transection to pudendal nerve transection ( p = 0.76 ) , indicating the long - term durability of pubo - urethral ligament transection on inducing
stress urinary incontinence in the female
rat . -
pubmed
CONCLUSIONS : Our results show that
pubo - urethral ligament deficiency in the female
rat induces long - term
stress urinary incontinence that is comparable to that in the established
stress urinary incontinence model via pudendal nerve transection . -
pubmed
Our novel
rat model could be used to investigate mechanisms of
stress urinary incontinence in females , including the role of
urethral hypermobility and potential therapeutic interventions for
stress urinary incontinence . -
pubmed
Ten consecutive
patients [ mean ( range ) age 26 ( 18 - 39 ) y ] with active colonic
CD ( mean CD activity index : 383.7 + /- 129.8 ) were prospectively included in the study . -
pubmed
Sequential defunctionalization followed by
thyroxine supplementation as preoperative preparation of
hyperthyroid patients undergoing thyroidectomy . -
pubmed
BACKGROUND : Preparing
hyperthyroid patients for thyroid surgery with a combination of antithyroid drugs and
thyroxine has long been controversial because this combination usually results in only partial inhibition of thyroid function . -
pubmed
METHODS : Four hundred and seventy - one
hyperthyroid patients seen at our hospital were divided into experimental and control groups . -
pubmed
CONCLUSIONS : Sequential thyroid defunctionalization followed by
thyroxine supplementation is effective in reducing the
bleeding volume and
postoperative complication rate in selected
hyperthyroid patients undergoing thyroidectomy . -
pubmed
In support of these observations , we report the occurrence of clinical
pneumonitis in 3
patients in association with
everolimus therapy after heart transplantation in the absence of other causative factors . -
pubmed
Sepsis resulting from
Enterobacter aerogenes resistant to
carbapenems after liver transplantation . -
pubmed
BACKGROUND :
Sepsis due to
Enterobacter aerogenes (
E. - pubmed
RESULTS : A 39 - year - old
man had a
biliary fistula and then was found to have multiple
liver abscesses through abdominal ultrasound and an abdominal computed tomography scan , and
carbapenem - sensitive
E. - pubmed
CONCLUSIONS : We first report an unusual case of
sepsis caused by
E. - pubmed
BACKGROUND : Novel therapies are necessary to improve outcomes for
patients with
squamous cell carcinomas (
SCC ) of the head and neck . -
pubmed
Historically ,
vaccinia virus was administered widely to
humans as a vaccine and led to the eradication of
smallpox . -
pubmed
At a multiplicity of infection ( MOI ) of 1 ,
GLV-1h68 was highly cytotoxic to the four cell lines , resulting in & gt ; or = 90 %
cytotoxicity over 6 days , and the remaining two cell lines exhibited & gt;45 %
cytotoxicity . -
pubmed
CONCLUSION : These results demonstrate significant oncolytic efficacy by an attenuated
vaccinia virus for infecting and lysing
head and neck SCC both in vitro and in vivo , and support its continued investigation in future clinical trials . -
pubmed
CONCLUSIONS : In this
patient - level pooled analysis , overall use of SES compared with BMS demonstrated persistent superior efficacy at 5 years in terms of a reduction in target vessel revascularization , without an increase in rates of
death ,
MI , or
stent thrombosis . -
pubmed
( The Initial Double - Blind Drug - Eluting Stent vs Bare - Metal Stent Study , NCT00233805 ; The Study of the BX Velocity Stent in the Treatment of De Novo Artery Lesions , NCT00381420 ; Study of
Sirolimus - Coated BX VELOCITY Balloon - Expandable Stent in Treatment of de Novo Native
Coronary Artery Lesions [ SIRIUS ] , NCT00232765 ; The Study of the BX VELOCITY Stent In
Patients With De Novo
Coronary Artery Lesions , NCT00235144 ) . -
pubmed
METHODS : We compared change in category (
animal and supermarket ) and letter ( F , A , S ) fluency among 239 participants in 3 groups : remained cognitively normal throughout follow - up ( n = 96 ) , developed
Alzheimer ' s Disease (
AD ; preclinical
AD , n = 21 ) , and with
AD at initial testing ( prevalent
AD , n = 122 ) . -
pubmed
RESULTS : At baseline , prevalent and preclinical
AD groups scored lower on
animal than letter fluency . -
pubmed
Overall ,
animal fluency declined faster than letter fluency ;
animal fluency declined significantly faster than letter fluency among cognitively normal and prevalent
AD participants . -
pubmed
Steeper declines on both fluency measures distinguish preclinical
AD from cognitively unimpaired
individuals . -
pubmed
Role of wearable and automatic external defibrillators in improving survival in
patients at risk for
sudden cardiac death . -
pubmed
Both devices have been shown in small series to be highly effective at restoring
sinus rhythm in
patients with a
ventricular tachyarrhythmia . -
pubmed
In order to evaluate the in vivo antioxidation activity , the serum metabolites of
emodin following intravenous and oral administrations were prepared from
rats and characterized , followed by investigating the effects on
2,2 '- azobis ( 2 - amidinopropane hydrochloride )-induced
hemolysis . -
pubmed
METHODS : Detailed data regarding mortality were available on all
patients undergoing aortic valve replacement for isolated
aortic stenosis during a 5 - year period in the southeast region of Sweden ( n=396 ) . -
pubmed
Multiple sclerosis (
MS ) is a devastating
neurological condition that mainly affects young
adults and is associated with long - standing morbidity . -
pubmed
Most research efforts to date have concentrated on the mechanisms of immune - mediated demyelination , whereas mechanisms of
axonal injury , the major determinant of
neurological deficits in
MS patients , have been elusive beyond observational analyses . -
pubmed
This review discusses current understanding of the pathology and novel clinical investigations of
axonal injury in
MS and the commonly used
MS animal model , experimental
autoimmune encephalomyelitis . -
pubmed
Occupational allergy to
bell pepper pollen in greenhouses in the Netherlands , an 8 - year follow - up study . -
pubmed
BACKGROUND : Pollen from
bell pepper plants cultivated in greenhouses are known to cause occupational
allergic disease . -
pubmed
A cross - sectional study among 472
bell pepper employees in 1999 estimated prevalences for sensitization to
bell pepper pollen of 28 % and for work - related
allergic symptoms of 54 % . -
pubmed
During the 8 - year follow - up , the cumulative incidence of sensitization to
bell pepper pollen was 9 % and of work - related
rhinitis 19 % . -
pubmed
CONCLUSION : Cumulative incidences for sensitization to
bell pepper pollen , work - related
rhinitis and
asthma symptoms were 9 % , 19 % and 8 % , respectively . -
pubmed
PURPOSE : The objective of the present study was to emphasise the oral and dental findings of a male
patient with the
Maroteaux - Lamy syndrome who successfully underwent bone marrow transplantation ( BMT ) at the age of 22 months . -
pubmed
BMT is a therapeutic treatment that is given to permanently replace any disorder caused due to the deficiency of enzymes in
patients with storage diseases . -
pubmed
Bluetongue virus serotype 8 ( BTV-8 ) infection reduces fertility of Dutch dairy
cattle and is vertically transmitted to offspring . -
pubmed
In the present study , we examined the function of
resveratrol in protecting
human lens epithelial
B-3 (
HLEB-3 ) cells against
H ( 2 ) O ( 2 ) induced cell
death and cell apoptosis , its role in reducing
H ( 2 ) O ( 2 ) induced intracellular reactive
oxygen species ( ROS ) accumulation , and investigated the mechanism by which
resveratrol underlies the effect . -
pubmed
An 83 - year - old female
patient received video - assisted cardiac surgery for excision of a left
atrial tumor . -
pubmed
The
patient was satisfied by the cosmetic healing of the
wound and was discharged eight days after the surgery . -
pubmed
We report a case of a
patient who incurred spontaneous
anterior dislocation of a mature
cataract which required prompt surgical removal . -
pubmed
METHODS : Sixty
patients with chronic
otitis media of the mucosal type , with
pars tensa perforations , were included in the study . -
pubmed
Oral administration of the KATP
channel opener diazoxide ameliorates
disease progression in a
murine model of
multiple sclerosis . -
pubmed
BACKGROUND :
Multiple Sclerosis (
MS ) is an
acquired inflammatory demyelinating disorder of the central nervous system ( CNS ) and is the leading cause of
nontraumatic disability among young
adults . -
pubmed
In this study , we have examined the effect of oral administration of KATP channel opener
diazoxide on induced experimental
autoimmune encephalomyelitis (
EAE ) , a
mouse model of
MS . -
pubmed
Mice were orally treated daily with
diazoxide or vehicle for 15 days from the day of
EAE symptom onset . -
pubmed
Oral treatment of
mice with
diazoxide ameliorated
EAE clinical signs but did not prevent disease . -
pubmed
In vivo ,
B16F10 melanoma bearing
mice seem not to be responsive to liposomal treatments of natural compounds . -
pubmed
Our analysis also suggested a higher miR-146a expression in
OSCC tissues of
patients carrying C polymorphism . -
pubmed
The present study concluded a higher prevalence of the pre - mir-146a C - variant was associated with
OSCC progression in
patients with this disease . -
pubmed
Vitamin D analogs are used for treatment of
secondary hyperparathyroidism in
patients with
chronic kidney disease in order to prevent
renal osteodystrophy ,
bone fracture and
pain . -
pubmed
Therefore , in everyday clinical practice ,
hypercalcemia and
hyperphosphatemia often limits the ability to suppress
secondary hyperparathyroidism in
patients with
chronic kidney disease . -
pubmed
The present thesis describes the first comparative study of
alfacalcidol and
paricalcitol and their ability to control the
disturbances in the mineral metabolism in hemodialysis
patients . -
pubmed
While free radicals and
inflammation constitute major routes of
neuronal injury occurring in
amyotrophic lateral sclerosis (
ALS ) , neither antioxidants nor non - steroidal anti - inflammatory drugs have shown significant efficacy in
human clinical trials . -
pubmed
RATIONALE : In clinical trials , homogeneous
emphysema patients have responded well to upper lobe volume reduction but not lower lobe volume reduction . -
pubmed
RESULTS :
Patients with homogeneous
emphysema received either upper or lower lobe volume reduction therapy based on findings of radionucleotide scintigraphy scanning . -
pubmed
A 57 - year - old
man presented a
skin lesion on the posterior region of the left forearm with extensive
necrosis of skin and subcutaneous layer involving the underlying muscle planes , caused by a venous extravasation of heroin that he reports having injected himself . -
pubmed
Efficacy of
omega-3 fatty acids supplementation in treatment of
uremic pruritus in hemodialysis
patients : a double - blind randomized controlled trial . -
pubmed
In this study , the effects of omega-3 for treatment of
pruritus were investigated in hemodialysis
patients . -
pubmed
At first , 22 hemodialysis
patients suffering from
pruritus with previous drug resistance were selected . -
pubmed
So it seems that
Omega-3 fatty acids could be used as an efficient drug for treatment of
pruritus in
uremic patients . -
pubmed
Outcome following decompressive craniectomy for malignant
middle cerebral artery infarction in
patients older than 70 years old . -
pubmed
Recent clinical trials demonstrated that early decompressive craniectomy reduce mortality rates and improves functional outcomes in healthy young
patients ( less than 61 years of age ) with a
malignant infarction . -
pubmed
The purpose of this study was to assess the efficacy of decompressive craniectomy in elderly
patients ( older than 70 years of age ) with a malignant
MCA infarction . -
pubmed
METHODS : Between February 2008 and October 2011 , 131
patients were diagnosed with malignant MCA
infarctions . -
pubmed
CONCLUSION : Decompressive craniectomy is effective for
patients with a malignant MCA
infarction regardless of their age . -
pubmed
Therefore , factors other than age should be considered and the treatment should be individualized in elderly
patients with
malignant infarctions . -
pubmed
Induction chemotherapy followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy with or without adjuvant chemotherapy for locoregionally advanced
nasopharyngeal carcinoma : meta - analysis of 1,096
patients from 11 randomized controlled trials . -
pubmed
Risk ratios of 1.90 ( 95%CI 1.24 - 2.92 ) , 2.67 ( 95%CI 0.64 - 11.1 ) , 1.04 ( 95%CI 0.79 - 1.37 ) , 0.98 ( 95%CI 0.27 - 3.52 ) were found for grade 3 - 4
leukopenia , grade 3 - 4
thrombocytopenia , grade 3 - 4 mucous membrane , and grade 3 - 4 hepatic hematologic and
gastrointestinal toxicity , the most significant toxicities for
patients . -
pubmed
This alleviates concerns about contrast use in
patients with
thyroid carcinoma interfering with adjuvant
radioiodine therapy . -
pubmed
Penicillin - induced
epileptiform activity elevates focal brain temperature in anesthetized
rats . -
pubmed
To elucidate a relationship between changes in focal brain temperature and severity of abnormal brain activity ,
epileptiform discharges and behavioral
seizures were induced by
Penicillin G in anesthetized
rats , and focal brain - temperature was measured . -
pubmed
Therefore , we present a typical case of
Meniere ' s disease in contrast to a
patient with an intralabyrinthine
schwannoma and
Meniere - like symptoms . -
pubmed
OBJECTIVES : The aims of this study were to investigate an alternative pre - treatment method for resin infiltration using 37 %
H3PO4 with a brush applicator and to evaluate the penetration effect of the infiltrant for masking the natural
white spot lesions ( WSLs ) in
human teeth . -
pubmed
We describe a
woman with extra luminal
gastrointestinal stromal tumour of the stomach that mimicked a left
hepatic tumour presenting as an
abdominal mass . -
pubmed
CASE PRESENTATION : A 51 - year - old
woman presented with a history of increasing
epigastric pain for two - months duration . -
pubmed
Mice were subcutaneously inoculated with 1 x 10(6 ) Lewis
carcinoma 3LL cells into the dorsum . -
pubmed
Further studies are necessary to evaluate the usefulness of this device in the diagnosis of
patients with
upper respiratory tract disorders . -
pubmed
CONTEXT : The natural progression of
metabolic abnormalities among
patients with
inherited autoinflammation is unclear . -
pubmed
In the present study
hesperetin exhibited a significant
cytotoxic effect in
human breast carcinoma MCF-7 cells in a concentration- and time - dependent manner without affecting normal (
HMEC ) as well as immortalized normal mammary epithelial cells (
MCF-10A ) . -
pubmed
Initially , the
patient was managed as ocular type of
myasthenia gravis , but after progression to
general limb weakness and
areflexia , the diagnosis of
chronic inflammatory demyelinating polyneuropathy was made . -
pubmed
Newer applications are emerging in the detection of left atrial appendage
thrombi and quantification of myocardial blood flow and volume in transplant
patients . -
pubmed
CONCLUSIONS : Maternal exposure to uncoated
Ag - NPs during pregnancy
impaired spatial cognition in
rat offspring . -
pubmed
MATERIALS AND METHODS : Prospective non - randomised study of 242 consecutive
patients with substernal
goiter out of 2258
patients ( 11 % ) who underwent thyroidectomy . -
pubmed
Animal models of
gastrointestinal and liver diseases . -
pubmed
Animal models of
visceral pain : pathophysiology , translational relevance , and challenges . -
pubmed
Animal models have played a pivotal role in our understanding of the mechanisms underlying the pathophysiology of
visceral pain . -
pubmed
This review focuses on
animal models of
visceral pain and their translational relevance . -
pubmed
In addition , the challenges of using
animal models to develop novel therapeutic approaches to treat
visceral pain will be discussed . -
pubmed
Staphylococcus aureus bacteraemia is often complicated by metastatic infectious foci . -
pubmed
Classification of
neurological abnormalities in
children with
congenital melanocytic naevus syndrome identifies magnetic resonance imaging as the best predictor of clinical outcome . -
pubmed
OBJECTIVES : To establish whether routine MRI of the CNS is a clinically relevant investigation in
children with multiple
CMN ( more than one at birth ) , and to subclassify radiological abnormalities . -
pubmed
METHODS : Of 376
patients seen between 1991 and 2013 , 289 fulfilled our criterion for a single screening CNS MRI , which since 2008 has been more than one
CMN at birth , independent of size and site of the largest
naevus . -
pubmed
RESULTS : Twenty - one per cent of
children with multiple
CMN had an abnormal MRI . -
pubmed
Any
child with a stepwise change in neurological / developmental symptoms or signs should have an MRI with contrast of the brain and spine to look for new
CNS melanoma . -
pubmed
We report a 4 months old
infant with
orbital rhabdomyosarcoma with poor outcome . -
pubmed
Call is made for need for more studies to determine appropriate local therapy in
infants with
rhabdomyosarcoma . -
pubmed
Hyperuricemia has an adverse impact on the prognosis of
patients with
osteosarcoma . -
pubmed
Patients with
osteosarcoma have poor prognosis and are often at high risk of
death . -
pubmed
Hyperuricemia had been suggested as a poor prognostic factor of several
cancers , but the prognostic role of
hyperuricemia in
osteosarcoma patients had not been assessed . -
pubmed
In the present study , we investigated the prognostic role of
hyperuricemia at baseline on the overall survival of
patients with
osteosarcoma . -
pubmed
Sixty
osteosarcoma patients with
hyperuricemia were matched ( 1:2 ) to 120
osteosarcoma patients without
hyperuricemia with similar age and gender . -
pubmed
Data from those
patients with
osteosarcoma were evaluated retrospectively . -
pubmed
Kaplan - Meier method showed that
patients with
hyperuricemia had shorter overall survival compared with those with
normouricemia ( P & lt ; 0.0001 , log - rank test ) . -
pubmed
In univariate analysis ,
hyperuricemia was associated with poorer overall survival in
osteosarcoma patients ( HR = 2.71 , 95 % CI 1.75 - 4.20 ; P & lt ; 0.0001 ) . -
pubmed
In conclusion ,
hyperuricemia at baseline is associated with poorer overall survival in
osteosarcoma patients , and it has an adverse impact on the prognosis of
osteosarcoma patients . -
pubmed
Incidence and clinical presentation of
myocardial ischemia in
patients with chronic
CAD in Italy : the ISPICA survey study . -
pubmed
METHODS : Thirty - six cardiology units located in different geographic areas of Italy enrolled a total of 1475
outpatients ( 73.6 % men and 26.3 % women ; mean age 71 + - 10 and 67 + - 9 years in men and women , respectively ) with a documented diagnosis of chronic
CAD . -
pubmed
difficile growth and prevented toxin production in a
human gut model of
CDI . -
pubmed
Eight
patients in Macintosh group had
tongue - lip - dental trauma during intubation , while only 2
patients received
upper airway trauma in Airtraq group . -
pubmed
The negative effects of overexposure to ultraviolet ( UV ) radiation in
humans , including
sunburn and light - induced
cellular injury , are of increasing public concern . -
pubmed
To date , little information is available about its
neurotoxicity during early
vertebrate development . -
pubmed
Our resent study is the first proof - in - principle that miRNA combination can be exploited to fine - tune the replication of
HSV-1 to treat
human cancers . -
pubmed
METHODS : Two - dimensional
polyacrylamide gel electrophoresis ( 2DE ) was used to separate the plasma proteins from
T2DM patients and healthy control subjects . -
pubmed
This area is of interest as it is impacted both in
human demyelinating diseases and in the
cuprizone model . -
pubmed
The use of fractional exhaled
nitric oxide is valuable in select
asthmatic patients . -
pubmed
FeNO can help the physician identify which
patients have
eosinophilic inflammation and would potentially respond to
corticosteroid therapy . -
pubmed
FeNO can be used in the initial diagnosis of
asthma and aid in stratification of which
patients would be
steroid responsive but also for assessment of disease severity , response to treatment , and compliance . -
pubmed
Tuberculosis , caused by the bacterium
Mycobacterium tuberculosis , remains one of the most serious global health problems . -
pubmed
Long - term efficacy and safety of
fingolimod in Japanese
patients with
relapsing multiple sclerosis : 3 - year results of the phase 2 extension study . -
pubmed
BACKGROUND : The low level of disease activity and manageable safety profile seen with
fingolimod versus placebo in a 6 - month , phase 2 , randomized controlled trial in Japanese
patients with
relapsing multiple sclerosis (
MS ; ClinicalTrials.gov Identifier NCT00537082 ) were maintained in the initial 6 - month observational study extension . -
pubmed
In
patients who switched to the active treatment , a 79.5 % decrease in annualized
relapse rate ( ARR ; from 1.131 before switch to 0.232 6 - months after switch ) was observed in the first 6 months of the extension phase and thereafter remained low until the end of study ( 0.16 - 0.31 across all assessment time points after switch up to end of study ) . -
pubmed
These results indicate that
fingolimod provides long - term treatment benefit for Japanese
patients with relapsing
MS . -
pubmed
Herein , we present the case of a 39 - year - old
female who presented right
ptosis on the follow - up of
breast cancer after surgery . -
pubmed
Patients Ten eyes of 10
patients with
retinal hemangioblastoma in
Hippel - Lindau disease were included . -
pubmed
Flying foxes have been considered to be involved in the transmission of serious
infectious diseases to
humans . -
pubmed
Data were collected by direct interview using a structured questionnaire consisting of the respondent characteristics ( age , sex and occupation ) ; histories of contacts between flying foxes and
humans ,
dogs and other domestic animals ; and knowledge about
infectious diseases , mainly
rabies , in flying foxes . -
pubmed
Murine model of
hepatic breast cancer . -
pubmed
To date , very few
murine models of
hepatic breast cancer exist . -
pubmed
METHODS : In this study , a novel
murine model of
liver breast cancer using the
MDA - MB-231 cell line is introduced as an experimental ( preclinical ) model . -
pubmed
Common features of the
murine model were vascular invasion , lung
metastasis and peritoneal seeding . -
pubmed
CONCLUSIONS : The novel
murine model of
hepatic breast cancer established in this study provides a tool to be used to investigate mechanisms of hepatic
metastasis and to test potential therapeutic interventions . -
pubmed
PURPOSE : We examined changes in visual function and ocular and retinal blood flow ( RBF ) among
retinitis pigmentosa (
RP )
participants in a randomized controlled trial of electro - stimulation therapies . -
pubmed
CONCLUSION : Increased blood flow following electro - stimulation therapies is an objective , physiological change that occurred in addition to visual function improvements in some
RP patients . -
pubmed
Ultrastructural Features of Neurovascular Units in a
Rat Model of Chronic Compressive
Spinal Cord Injury . -
pubmed
Objective of this study is to assess the ultrastructural features of the neurovascular unit ( NVU ) in a
rat model of chronic compressive
spinal cord injury , 24 SD
rats were divided into two groups : the control group ( n = 12 ) , and the compression group ( n = 12 ) . -
pubmed
The small
hive beetle ,
Aethina tumida Murray ( Coleoptera : Nitidulidae ) , is a pest of colonies of social bees , including the
honeybee Apis mellifera L. ( Hymenoptera : Apidae ) . -
pubmed
Also discussed was the topic of
cutaneous melanoma murine models outlining the role of these models in understanding the molecular pathways involved in
melanoma initiation , progression , and
metastasis . -
pubmed
Chronic Kidney Disease and
Hepatitis C Virus Treatment . -
pubmed
On that ground ,
patients with these
lymphomas should be strictly monitored . -
pubmed
We aim to identify serum inflammatory mediators that are associated with outcome after
intracerebral hemorrhage in order to translate data from experimental models to a
patient cohort and identify potential targets worthy of reverse translation . -
pubmed
Methods : A prospective cohort study at two comprehensive
stroke centers enrolled
patients with spontaneous
intracerebral hemorrhage . -
pubmed
Interpretation : Acute and subacute elevations in specific immune factors are associated with poor outcome , highlighting potential pathways that may contribute to ongoing
brain injury in
patients with
intracerebral hemorrhage . -
pubmed
Methods : Forty - five dental implants in 20
patients diagnosed with
peri - implantitis were included . -
pubmed
BACKGROUND :
Schistosoma mansoni infection has been associated with increased risk of
HIV transmission in African women . -
pubmed
METHODS :
HIV - uninfected non - pregnant adult women using public health services were tested for
schistosomiasis using the urine circulating cathodic antigen test , followed by serology and Schistosoma spp.-specific PCR . -
pubmed
All women infected by
Chlamydia trachomatis ( n = 5 ) , were also positive for
schistosomiasis ( Fisher 's exact p = 0.064 ) . -
pubmed
These findings have implications for the design and interpretation of clinical studies on the effects of
schistosomiasis on
HIV acquisition . -
pubmed
Thyme oil also showed antibacterial activity against
MRSA and the antibiotic - sensitive
strain of
P. - pubmed
The aim of this study was to assess
patient compliance , satisfaction and experience with the extended low molecular weight
heparin prophylaxis after major surgery for
gynaecological cancer . -
pubmed
Consecutive
patients undergoing surgery for
gynaecological cancer who received
low molecular weight heparin prophylaxis for four weeks following surgery were recruited . -
pubmed
Daily adjustment of glucocorticoids by
patients with
adrenal insufficiency . -
pubmed
AIM : To evaluate self - management of
patients with
AI . -
pubmed
METHODS : We examined 781
patients who underwent hepatic resection for
HCC . -
pubmed
Successful management and recovery following severe prolonged
starvation in a
dog . -
pubmed
CASE SUMMARY : A 7 - year - old , intact male
Labrador Retriever presented with profound
weakness and loss of nearly 50 % of his
body weight due to severe prolonged
starvation after being trapped in a well for 27 days . -
pubmed
The
dog 's
electrolyte abnormalities resolved ,
wounds healed , and strength returned during the first 3 weeks of treatment . -
pubmed
NEW OR UNIQUE INFORMATION PROVIDED : This report describes the management of a severely malnourished
dog during refeeding , and highlights treatment considerations that may be important in the prevention of
refeeding syndrome in such cases . -
pubmed
Results : In
patients with premenopausal
breast cancer , the
tumour diameter was larger ( p = 0.047 ) and the lymph node
metastasis was higher ( p & lt ; 0.001 ) . -
pubmed
The chapeau de gendarme sign has been associated with
frontal lobe seizures in
patients with
focal epilepsy . -
pubmed
We propose that the anterior insular cortex should be a site of investigation during pre - surgical phase 2 evaluation in
patients exhibiting the chapeau de gendarme sign during focal
seizures . -
pubmed
Cistanche deserticola Y. C. Ma is known as a popular tonic herb traditionally used to treatment
deficiency of kidney energy including
muscle weakness in minority area of Asian counties . -
pubmed
Based on the theory of " kidney dominate bone , " an ovariectomized ( OVX )
rat model of
postmenopausal osteoporosis was used to evaluate the therapeutic effect of
C. - pubmed
CONCLUSIONS : Overall psychological interventions for
children and adults with
type 1 diabetes do not improve glycaemic control . -
pubmed
NCBP2modulates
neurodevelopmental defects of the 3q29 deletion in
Drosophila and
Xenopus laevis models . -
pubmed
Ultrasound Neuromodulation Inhibits
Seizures in Acute
Epileptic Monkeys . -
pubmed
Recent studies have reported that ultrasound stimulation suppressed
epileptic seizures in a
rodent model of
epilepsy . -
pubmed
These findings raise the crucial question of whether ultrasound stimulation can inhibit
seizures in non -
human primates with
epilepsy . -
pubmed
We confirmed that ultrasound stimulation significantly reduced the frequency of
seizures in acute
epileptic monkeys . -
pubmed
Our results are of great importance for future clinical applications of ultrasound neuromodulation in
patients with
epilepsy . -
pubmed
RESULTS : We identified 35 articles including 2042 primary
EOC patients ; one study was a randomized trial , and only six studies included a comparator group of surgery alone . -
pubmed
[ Establishment and evaluation of multiplex PCR for detection of main pathogenic bacteria of
endometritis in
Tibetan sheep ] . -
pubmed
A multiplex PCR method was developed to detect the main pathogens of
Qinghai Tibetan sheep endometritis . -
pubmed
The multiplex PCR method was successfully established and the main pathogens of
endometritis in Qinghai Tibetan sheep were
GBS ,
E. - pubmed
The invitro PDT is tested on
murine breast
4T1 cancer cells incubated with 250 mug / mL of the nanoparticles and irradiated with NIR light under power density of 2 W / cm2for 10 minutes . -
pubmed
Immunohistochemistry , Kaplan - Meier method and multivariate Cox regression assays were performed to examine the clinical correlation in
tumor specimens from
lung cancer patients . -
pubmed
The inclusion of straw in high concentrate total mixed rations ( TMRs ) of male fattening
goats can provide the necessary fiber to prevent ruminal
acidosis and maintain growth . -
pubmed
Thirty - two male
Beetal goats ( 27.4 + - 0.28 kg
body weight ( BW ) ) were divided randomly into the following four dietary treatments with a 2 x 2 factorial arrangement ( n = 8 / treatment ): ( 1 ) CTMR15 ( conventional TMR containing 15 % WS ) , ( 2 ) CTMR25 ( conventional TMR containing 25 % WS ) , ( 3 ) PTMR15 ( pelleted TMR containing 15 % WS ) , and ( 4 ) PTMR25 ( pelleted TMR containing 25 % WS ) . -
pubmed
Ten healthy right - handed
volunteers without any
neurological disorders were enrolled . -
pubmed
When the objects were placed on the unreachable
spot ,
dogs looked at both objects for the same amount of time in the non - matching group , but longer at the toy in the matching group . -
pubmed
Infection with
Toxoplasma gondii is usually an asymptomatic or oligosymptomatic , self - limiting disease in immunocompetent individuals . -
pubmed
Intracranial lipomata can be found in both symptomatic and asymptomatic
patients . -
pubmed
Tumor - associated humoral cytotoxicity in
patients with
acute myelogenous leukemia before and after chemotherapy . -
pubmed
Sera of eight unselected adult
patients with
acute myelogenous leukemia obtained before and after chemotherapy were repeatedly tested for specific complement - dependent
cytotoxicity against autochthonous peripheral white blood cells from the
acute leukemia stage and from the remission stage , respectively . -
pubmed
The
cytotoxicity was increased after chemotherapy , also in those
patients in whom remission was not achieved . -
pubmed
Enumeration of
Streptococcus mutans in
human dental plaque after chewing gum sweetened with
xylitol and
sucrose . -
pubmed
Liver changes were demonstrated in six elderly
patients with
giant - cell arteritis (
temporal arteritis , three with
polymyalgia ) . -
pubmed
28
patients with advanced
mitral valve restenosis were studied by cardiac catherization on an average of 7.2 years after previous closed mitral valvotomy , performed using the Tubbs dilator technique . -
pubmed
Report on a
man of 29 years with acute
bronchopneumonia , antibodies against
Mycoplasma pneumoniae and acute
pancreatitis lasting three weeks . -
pubmed
Lymphocytes isolated from tonsils of
patients undergoing tonsillectomy and from axillary lymph nodes of
breast cancer patients exhibited approximately 30 % of cells with caps , which is identical with the cap formation ability of normal lymphocytes . -
pubmed
In biopsy material from
patients with
Hodgkin ' s disease and other
malignant lymphomas , a significant decrease in the ability of the lymphocytes to form caps was observed . -
pubmed
In 123
patients with
Hodgkin ' s disease and other
malignant lymphomas , cap formation ranged between 3 and 12 % . -
pubmed
Lymphocytes from
patients with
lymphoma were also agglutinated by Con A to a higher degree than normal lymphocytes . -
pubmed
Immunological function in
patients operated on with small intestinal shunts for morbid
obesity . -
pubmed
Obese individuals , operated on with intestinal shunts , have been investigated with regard to immunological functions . -
pubmed
This study identified 2438
human immunodeficiency virus (
HIV)-seropositive active - duty enlisted Navy personnel , including 778 seroconverters . -
pubmed
Focal glomerulosclerosis in
children : an Argentinian experience . -
pubmed
Twenty - six
children presenting with
idiopathic nephrotic syndrome and a histological diagnosis of
focal glomerulosclerosis were studied retrospectively to evaluate their response to treatment , outcome and clinicopathological correlations . -
pubmed
Twenty - two
patients ( 84.6 % ) were
steroid resistant ; of these , 8 of the 19 with
focal segmental glomerulosclerosis and 2 of the 3 with focal global
glomerulosclerosis responded to
cyclophosphamide (
CY ) within 16 weeks of starting therapy . -
pubmed
After an average follow - up of 83 months , 17
patients are in remission with normal renal function , 3
patients have persistent
nephrotic range
proteinuria and 6
patients are in
chronic renal failure . -
pubmed
Effects of
pentisomide and
E-4031 on
canine atrial flutter due to reentry : a comparative study with
disopyramide and
propafenone . -
pubmed
AF was induced with burst atrial pacing after we made an intercaval crush in anesthetized , open - chest
dogs . -
pubmed
Pentisomide and
E-4031 were effective in terminating
canine AF due to reentry , as were
disopyramide and
propafenone . -
pubmed
Reinitiation of
AF was greater in
dogs treated with antiarrhythmic drugs that had more prominent effects on conduction time than on ERP . -
pubmed
In the experiment on 60
dogs , it was established that the leading causes of unsatisfactory anastomotic healing in
peritonitis were the disorders in hemocirculation and morphologic changes in the intestinal wall . -
pubmed
The
patient was pointed out to have
papilledema and
elevated intracranial pressure six years ago . -
pubmed
Consequently , she was diagnosed as the benign
intracranial hypertension and had been followed as an out
patient . -
pubmed
Data collected to investigate the effects of
ticlopidine in a subset of 489
patients with
angina at rest accompanied by transient ischaemic electrocardiographic changes have been analysed . -
pubmed
Nineteen
patients died ; 12 in the control group ( 4.7 % ) and seven in the
ticlopidine group ( 83 % ) ( -36 % ) ( odds ratio : 0.62 ; confidence intervals : 0.21 , 1.74 ) ; five
patients in the control group and only one in the
ticlopidine group died of an
AMI . -
pubmed
Heparin prevents stasis - induced
thrombosis through protection of the venous endothelial cells : an electron microscopic study in
rabbits . -
pubmed
Alterations in the pattern of epidermal differentiation and proliferation occur during
mouse skin
carcinogenesis . -
pubmed
However , in
carcinomas , the transcript levels for the Mr 67,000 and 59,000 subunits were only 1 - 3 % of those observed in untreated
mouse epidermis . -
pubmed
The effects of
2,2 '- O - cyclocytidine (
CC ) and
acyclovir (
ACV ) on latent
herpes simplex virus ( HSV ) in trigeminal
ganglia were studied in an in vitro model using reactivation of HSV type 1 (
HSV-1 ) as a model . -
pubmed
Therefore , the attempts to correct these neurohormonal imbalance in
patients with
heart failure has a sound rational basis , not only to improve the symptoms and the exercise capacity but also to increase the survival of these
patients . -
pubmed
Examination of oxidative metabolism in mitochondria isolated from quadriceps skeletal muscle biopsy specimens of 4
patients with
Kearns - Sayre syndrome has shown that the mitochondria were tightly coupled , with maximal respiratory rates depending on the presence of
adenosine diphosphate (
ADP ) ,
Ca2 + , or uncoupler . -
pubmed
Deficient glucagon responses to decrements in plasma
glucose , which are common in
patients with
IDDM and occur in some patients with
NIDDM , result in altered counterregulation . -
pubmed
Studies of
verrucofortine toxicity in
mice showed no apparent toxic effects at doses as high at 160 mg / kg ip . -
pubmed
Bone marrow cells from most
patients with
acute promyelocytic leukemia contain a highly specific cytogenetic rearrangement , a reciprocal translocation between the long arms of chromosomes 15 and 17 . -
pubmed
[ Immunocorrective therapy of
patients with
chronic active liver diseases of a viral nature ] . -
pubmed
A study of the effect of immunocorrective drugs on the clinicobiochemical and immunological indices of
patients with chronic active
liver diseases of viral nature made it possible to work out criteria for administration of
levamisole ( the absence of the
cytolytic syndrome , the presence of
immunodeficiency in the system of cellular immunity and disturbance of immunoregulation ) ,
prednisolone , the combination of
prednisolone and
azathioprine , and
d - Penicillamine ( severe
hepatocellular insufficiency , the presence of
autoimmune reactions and disturbance of immunoregulation ) . -
pubmed
The pharmacokinetics of
ceftriaxone (
CRO ) after subcutaneous and intravenous administration was studied in 10 healthy
volunteers ( 5
males , 5
females , age 22 - 43 years ,
body weight 64.3 + /- 9.5 kg ) . -
pubmed
[ Immunochemical studies in various
human myopathies ] . -
pubmed
Oxygen consumption and tissue
oxygen tension as a function of the hematocrit in
polycythemic mice . -
pubmed
jousseaumei ; the latter is probably the snail host of
Schistosoma haematobium in one small village in the delta , where a low
infection rate was reported by other workers . -
pubmed
Preliminary data on the
dexamethasone suppression test in
children with
major depressive disorder . -
pubmed
The authors administered the
dexamethasone suppression test to 14
children aged 5 - 12 years who met the Research Diagnostic Criteria and DSM - III criteria for major
depressive disorder . -
pubmed
2
patients developing acute
alveolar hypoventilation following IPPB therapy are presented . -
pubmed
There is a significant diminution in intracellular bactericidal activity of leukocytes with
Staphylococcus aureus and
Escherichia coli in subjects with poorly controlled
diabetes in comparison with the control group . -
pubmed
The indication for surgery was
rest pain in 22
patients and actual tissue
necrosis in 43
patients . -
pubmed
Their antiproliferative effect has been found against a variety of
animal and
human tumor cell lines . -
pubmed
We have characterized the cytostatic activity of four
ether phospholipids , the
methoxy - substituted edelfosine (
ET-18 - OCH 3 ) , the
thio - derivative
ilmofosine ( BM 41.440 ) , and two new
aza - alkylphospholipids ,
BN 52205 and
BN 52211 , on a
human tumor cell line derived from a
colon adenocarcinoma , the
HT29 . -
pubmed
We examined the effect of
hypercholesterolemia on vasodilatory responses to
clonidine in isolated and perfused
rabbit common carotid arteries that had been preconstricted by
phenylephrine . -
pubmed
In 7
children impairment of hearing was observed after local therapy with
neomycin and
gentamicin because of
scalding wounds . -
pubmed
3
adults locally treated with
aminoglycoside antibiotics (
neomycin ,
framycetin ,
gentamicin ) for
ulcera cruris displayed a delayed development of
hearing loss . -
pubmed
[ The combined treatment of
patients with locally disseminated
prostatic cancer ] . -
pubmed
A randomized study has been made to compare combined treatments of 111
patients with local
prostatic cancer ( T2b-4N0 - 2M0 ) . -
pubmed
Cytotoxicity of endogenous
isoquinolines to
human dopaminergic
neuroblastoma SH - SY5Y cells . -
pubmed
In this paper they were examined for the
cytotoxicity of
human dopaminergic
neuroblastoma SH - SY5Y cells . -
pubmed
Their baseline levels were found to be higher in
patients with
cancer of the lung , large bowel , and rectum than those in controls , which indicates higher lipid peroxidation , which led to the destabilization of cellular membranes and seems to cause baseline
hypermyoglobinemia . -
pubmed
Usefulness of subnormal midwall fractional shortening in predicting
left ventricular exercise dysfunction in asymptomatic
patients with
systemic hypertension . -
pubmed
However , it is unknown whether abnormal midwall fractional shortening predicts either subnormal LV functional reserve or
extracardiac damage in asymptomatic hypertensive
patients . -
pubmed
Thus , subnormal midwall fractional shortening predicts depressed LV fractional reserve in asymptomatic
hypertensive patients and may contribute to identification of
patients with
extracardiac target - organ damage . -
pubmed
The performance of the whole system was tested on
dog plasma samples including specimens taken after oral administration of the anti -
Parkinsonism drug
Duellin , which is a combination tablet of
levodopa and
carbidopa . -
pubmed
METHODS : This single - center , randomised , double - blind study was conducted on 37
women with chronic lower - limb
venous insufficiency , associating clinical or functional signs and abnormal plethysmographic values . -
pubmed
Cost - effectiveness analysis of a dry powder inhaler ( Turbuhaler ) versus a pressurised metered dose inhaler in
patients with
asthma . -
pubmed
In an open randomised parallel - group study , 1004
patients with
asthma in 7 countries were randomised to receive
asthma treatment via 2 different kinds of inhalers : an aerosol pressurised metered dose inhaler ( pMDI ) and a dry powder inhaler ( Turbuhaler ) . -
pubmed
Lexical and conceptual components of stem completion priming in
patients with
Alzheimer ' s disease . -
pubmed
This study evaluated the hypothesis of dissociation between normal lexical but deficient conceptual repetition priming in
patients with
Alzheimer ' s disease (
AD ) . -
pubmed
For this purpose , we administered to
patients with
AD and age - matched normal controls the Stem Completion task . -
pubmed
Probably due to a floor effect of performance in the graphemic condition , in Experiment 1 ,
AD patients exhibited lower priming than normal controls for the semantically processed words but comparable priming for the graphemically processed ones . -
pubmed
In contrast , in Experiment 2 ,
AD patients were poorly primed both in the intra- and crossmodal conditions . -
pubmed
Results question the hypothesis of a lexical / conceptual dissociation in the repetition priming exhibited by
AD patients and call for other explicative hypotheses of the dissociation between normal and deficient forms of repetition priming in
degenerative dementia . -
pubmed
METHODS : Seven
patients afflicted by
neurogenic velopharyngeal incompetence were treated with wire - extension speech - aid prostheses constructed to circumvent the
dysfunctional soft palate . -
pubmed
CONCLUSION : Wire - extension speech - aid prostheses used by the
patients were an effective treatment approach for
velopharyngeal incompetence . -
pubmed
Cholesterol standardized plasma
vitamin E levels are reduced in
patients with severe
angina pectoris . -
pubmed
Vitamin E , the major lipid soluble plasma antioxidant , has been reported to be reduced in
patients with
coronary atherosclerosis . -
pubmed
We have measured the levels of plasma
alpha - tocopherol ( the predominant form of plasma
vitamin E ) in 128
patients with different reported degrees of
angina . -
pubmed
The groups of
patients with
angina did not differ significantly for mean age ( 58 + /- 1.0 years vs. 59 + /- 1.0 years , respectively ) ; sex distribution ( the M : F ratio was 48 : 16 and 46 : 18 for the respective groups ) ; or prevalence of smoking ( 12 % vs. 9 % ) , or
hypertension ( 19 % vs. 33 % ) . -
pubmed
The ratio between plasma
vitamin E : total
cholesterol was significantly lower in the
patients with severe
angina ( mean 2.20 + /- 0.09 mg / mmol ) vs. a mean value of 2.46 + /- 0 . -
pubmed
The plasma
vitamin E : total
cholesterol ratio in
patients with severe
angina was also significantly lower ( P & lt ; 0.05 ) compared to either healthy controls with comparable total
cholesterol levels ( n = 33 ) , or
hypercholesterolaemic subjects ( n = 28 ) without symptomatic
coronary disease ( mean ratios were 2.69 + /- 0.40 mg / mmol and 2.74 + /- 0.68 mg / mmol , respectively ) . -
pubmed
Child and adolescent
cancer patients who use
tobacco present challenging management problems for the pediatric dentist . -
pubmed
An approach to counseling patients about their oral health risks secondary to their
cancer treatment , which can be adversely impacted by
tobacco use , is discussed . -
pubmed
Strategies for conducting dental examinations with pediatric
cancer patients with attention to potential
tobacco - related complications are also provided . -
pubmed
METHODS : Two hundred
subjects ( aged 51 - 88 years ) , 99 with and 101 without
AAA as determined by previous ultrasound , each underwent physical examination of the abdomen by 2 internists who were blinded to each other 's findings and to the ultrasound diagnosis . -
pubmed
We present the case of a
patient with
psoriasis in whom ulcerated
atrophic striae developed during
etretinate therapy . -
pubmed
Subsequently , the
patient had a favorable response to oral
calcitriol (
1,25 - dihydroxy vitamin D3 ) , a novel therapy for
psoriasis . -
pubmed
Abdominal lump in an infertile
man . -
pubmed
Alcohol and
tobacco consumption may contribute to synchronous or
metachronous head and neck cancer and
esophageal cancer . -
pubmed
Five
patients ( 8.3 % ) had superficial
esophageal cancer , which was diagnosed as intraepithelial
carcinoma in three of them ( 5.0 % ) . -
pubmed
Treatments that weaken Pavlovian conditioned fear and thwart its renewal in
rats : implications for treating
human phobias . -
pubmed
In experiments using a total of 144 albino
rat subjects , the authors assessed the ability of fear - weakening treatments to prevent fear renewal (
relapse ) . -
pubmed
We assessed whether the quantification of
cancer invasion into the perineural space influences the prognosis of
patients treated with radical prostatectomy . -
pubmed
We conducted a retrospective study of clinical and pathologic features in 640 consecutive
patients with clinical stage Tla - T3bNXM0
prostate cancer who were treated with radical retropubic prostatectomy by the same surgeon between 1989 and 1995 . -
pubmed
PATIENTS AND METHODS : Fourteen
patients with severe
atopic blepharitis were treated with topical
FK 506 0.1 % . -
pubmed
Every
patient graded
pruritus on a visual analogue scale . -
pubmed
Effects of exercise training program on functional capacity and quality of life in
patients with
peripheral arterial occlusive disease . -
pubmed
During course of intervention ,
patients demonstrated improvements in
pain - free training walking distance ( p & lt ; 0.001 ) and repetitions of tiptoe standing ( p & lt ; 0.05 ) . -
pubmed
Effect of ovariectomy ,
malnutrition and glucocorticoid application on bone properties in
sheep : a pilot study . -
pubmed
The demographic changes in the
human population continue to lead to an increasing incidence of
osteoporosis . -
pubmed
There is a great need for a large -
animal model of
osteoporosis for controlled studies , which allows the investigation of
fracture healing and
fracture treatment in weak bone . -
pubmed
The most effective method of inducing
osteoporosis in
sheep was found to be the combined treatment . -
pubmed
Here we report the analysis of muscle biopsies from a
DMD patient (
DMD - BMT1 ) who received bone marrow transplantation at age 1 year for
X - linked severe combined immune deficiency and who was diagnosed with
DMD at age 12 years . -
pubmed
Seven
patients were classified as suffering from
Wegener ' s granulomatosis (
WG ) , 18 from
microscopic polyangitis (
MPA ) , and the remaining 19 were unclassified ( unclassified
small vessel vasculitis ,
USVV ) . -
pubmed
RESULTS : The percentage of ENT manifestations in the early clinical picture of
WG patients was 86 % , dropping to 44.5 and 22 % for
MPA and USVV patients , respectively . -
pubmed
The overall percentage of ENT manifestations for
SVV patients in their initial clinical profile was 47 % . -
pubmed
CONCLUSION : The results of our investigation highlight the importance of an ENT clinical examination as a guide for diagnosis of an important percentage of
SVV patients . -
pubmed
Epithelial
splenic cysts in
children : surgical treatment by
cyst - wall " peeling " . -
pubmed
Five consecutive
splenic epithelial cysts in pediatric
patients were treated by parenchyma - sparing complete removal of the
cyst wall , which was gently peeled off the splenic tissue without major
bleeding in all but one case . -
pubmed
PURPOSE : The use of partial breast brachytherapy ( PBB ) after lumpectomy for selected
patients with early - stage
breast cancer reduces the adjuvant radiotherapy treatment time to & lt;1 week . -
pubmed
METHODS AND MATERIALS : Early - stage
breast cancer patients with clear
resection margins and 0 - 3 positive lymph nodes were eligible for PBB . -
pubmed
RESULTS : Between 1995 and 2000 , 44
patients with early - stage
breast cancer received
PBB without adjuvant external beam radiotherapy after lumpectomy ( 31 HDR PBB , 13 LDR PBB ) . -
pubmed
Radiation recall reactions occurred in 43 % of
patients ( 6 of 14 ) who received
adriamycin . -
pubmed
FACTORS ASSOCIATED WITH ANAPHYLACTIC REACTIONS TO
CHICKEN EMBRYO
FOOT - AND - MOUTH DISEASE VACCINE AND FLURY
RABIES VACCINE IN CATTLE OF VENEZUELA . -
pubmed
We report a 50 - year - old
man with
CBD stone formed around a surgical clip , who had undergone a laparoscopic cholecystectomy because of acute calculous
cholecystitis 14 months before . -
pubmed
OBJECTIVES : To evaluate the outcome of immunocompetent pediatric
patients who had positive
cytomegalovirus ( CMV ) antigenemia and received
ganciclovir . -
pubmed
RESULTS : Sixty - four
patients with positive
CMV antigenemia were identified ; 15
patients were excluded from the study because of their underlying diseases . -
pubmed
We studied efficacy of predicting outcomes of the disease in 345
patients ( mean age 48.3 + /- 4.5 years ) with extra hospital
pneumonia (
EHP ) . -
pubmed
Recurrent
Mycobacterium marinum tenosynovitis of the wrist mimicking
extraarticular synovial chondromatosis on MR images . -
pubmed
Tenosynovitis caused by atypical
mycobacterial infections may produce
rice bodies within affected tendon sheaths . -
pubmed
marinum
infection involving the flexor tendons within the carpal tunnel in which the
rice bodies were mistaken for
synovial chondromatosis on MR images . -
pubmed
Recently , MRSI was successfully integrated into radiotherapy planning in
prostate cancer patients . -
pubmed
Whereas immune suppression is considered as a likely mechanism for exhaustive exercise - induced susceptibility to
infection , we know little about viral - specific T - cell response following exhaustive exercise in young or old
mice . -
pubmed
In this study , one group of female young ( 10 - 12 wk ) and old ( 22 - 24 mo ) C57BL/6
mice was exposed to a single bout of intense exercise to exhaustion and immediately infected with
lymphocytic choriomeningitis virus (
LCMV ) . -
pubmed
Its overexposure in
human beings can provoke significant effects including
lung , cardiovascular and kidney diseases . -
pubmed
Oral therapy with
dipyridamole limits
ischemia -
reperfusion injury in
humans . -
pubmed
We hypothesize that treatment with the
nucleoside uptake inhibitor
dipyridamole increases endogenous
adenosine and limits
ischemia -
reperfusion injury in
humans . -
pubmed
Population dynamics of nasal
strains of
methicillin - resistant
Staphylococcus aureus -- and their relation to community - associated disease activity . -
pubmed
METHODS : A randomized , controlled trial was used in Study 1 to compare a comprehensive family - based behavioral treatment program or an experimental treatment that incorporated reinforcing
children for engaging in alternative behaviors to eating for 41
overweight 8- to 12 - year - old children . -
pubmed
Study 2 used a within - subject design with baseline , enriched environment and a second baseline phase to determine the influence of providing activities that compete with eating for 13
overweight 8- to 12 - year - old
children . -
pubmed
We conducted a systematic review to assess the benefits and harms of
ribavirin monotherapy for
patients with
chronic hepatitis C. -
pubmed
It is suggested that
Eptein - Barr virus (
EBV ) that contains the above deletion is not crucial for the development of the study
lymphoproliferative malignancies . -
pubmed
Etiology and effect on outcomes of
hyperglycemia in hospitalized
patients . -
pubmed
PURPOSE : The prevalence of
diabetes in U.S. hospitals , etiology and pathophysiology of
hyperglycemia in hospitalized
patients , impact of
hyperglycemia on
patient outcomes , and benefits of
hyperglycemia correction are described . -
pubmed
SUMMARY :
Diabetes mellitus is a common and costly condition with an increasing prevalence in the U.S.
Hyperglycemia is common among hospital
patients with and without
diabetes . -
pubmed
The benefits of using intensive therapy to correct
hyperglycemia in hospitalized
patients in reducing mortality and the risk of
infections and other adverse outcomes are well documented . -
pubmed
CONCLUSION : Efforts are needed to manage
hyperglycemia in hospitalized
patients with and without
diabetes to minimize the morbidity , mortality , and costs associated with
hyperglycemia . -
pubmed
More than 400 million
people are susceptible to oxidative stress due to
glucose-6 - phosphate dehydrogenase ( G6PD ) deficiency . -
pubmed
[ The effectiveness of
fenspiride in the treatment of
patients with
chronic obstructive pulmonary disease ] . -
pubmed
The purpose of the study was to assess the effectiveness and safety of long - term application of
fenspiride , an anti - inflammatory drug , in
patients with
chronic obstructive pulmonary disease (
COPD ) under outpatient conditions . -
pubmed
The drug was studied on 24
COPD patients . -
pubmed
Coronary artery disease (
CAD ) was diagnosed in 92 ( 53 % )
patients , and non -
ischaemic cardiomyopathy in 82 ( 47 % )
patients . -
pubmed
Indications for repeat procedures included battery depletion in 136
patients , ICD malfunction in 37 cases ,
infection related to the implanted system in 5 patients , problems with leads in 19 cases , an upgrade to the dual - chamber system in 5 or to the biventricular system in 3
patients , and the revision of an ICD pocket in 6 patients . -
pubmed
Clinically useful " older " agents include topical
azole formulations ( for superficial
yeast and
dermatophyte infections ) , first - generation
triazoles (
fluconazole and
itraconazole , for a range of superficial and invasive
fungal infections ) ,
amphotericin B formulations ( for a broad range of invasive
fungal infections ) and
terbinafine ( for
dermatophyte infections ) . -
pubmed
Caspofungin and the other
echinocandins are effective in treating
Candida and
Aspergillus infections . -
pubmed
Further , it can also promote full - thickness cutaneous
wound healing in
BALB / c mice . -
pubmed
Serious
paravalvular leakage occurs in 1 - 5 % of
patients who have undergone surgical cardiac valve replacement procedures . -
pubmed
[ Effectiveness of prophylaxis against
tuberculosis in patients infected with
HIV ] . -
pubmed
INTRODUCTION : Prophylaxis against
tuberculosis has been recognized as important for preventing clinical forms of
tuberculosis , mainly in
HIV positive patients . -
pubmed
The second group consisted of 200 patients selected from the records of a
HIV /
AIDS control program . -
pubmed
CONCLUSION : The prophylaxis against
tuberculosis was effective in
HIV positive
patients , independently of the immune status , viral load , and highly effective antiretroviral therapy . -
pubmed
The author presents the case of a 62 - year - old obese Hispanic
man , with newly diagnosed
type 2 diabetes mellitus (
T2DM ) ,
diabetic peripheral neuropathy , background
retinopathy , and
diabetic nephropathy . -
pubmed
In the present study , adult feeding and population density of the weevil ,
injury level of
striped stem borer Chilo suppressalis ( Walker ) ( Lepidoptera : Pyralidae ) and
pink stem borer Sesamia inferens ( Walker ) ( Lepidoptera : Noctuidae ) to
rice , as well as growth status of their host plants were surveyed in a
rice field located in Southeastern Zhejiang , China , in 2004 with the objective to discover interspecific interactions on the rice . -
pubmed
MATERIALS AND METHODS : The treatment data of 7
patients with
VMs from January 2005 to January 2006 were reviewed . -
pubmed
Two
patients had a
fever during treatment , and one of them stopped treatment because of continuous high
fever . -
pubmed
Acute renal failure after exercise in a
Japanese sumo wrestler with
renal hypouricemia . -
pubmed
Dietary high protein and
vitamin C mitigates
endosulfan toxicity in the
spotted murrel ,
Channa punctatus ( Bloch , 1793 ) . -
pubmed
Unique patterns of molecular profiling between
human prostate cancer LNCaP and
PC-3 cells . -
pubmed
BACKGROUND :
Human prostate cancer LNCaP and
PC-3 cell lines have been extensively used to study
prostate cancer progression and to develop therapeutic agents . -
pubmed
One
animal was excluded from the study due to complications in the
TG during
wound healing ; therefore , six
dogs remained in the sample . -
pubmed
Dog skin was sutured after punch biopsy and investigated histologically and immunohistochemically on days 0 ( normal ) , 1 , 3 , 5 , 7 , 10 , and 14 after
injury . -
pubmed
A
human cadaver emergency procedure lab curriculum is uncommon . -
pubmed
Response averages and 95 % confidence intervals for the preferred means of learning a new procedure are as follows : textbook ( 3.69 ; 3.51 - 3.87 ) , mannequin ( 2.83 ; 2.64 - 3.02 ) ,
human cadaver ( 1.93 ; 1.72 - 2.14 ) , and living patient ( 1.56 ; 1.33 - 1.79 ) . -
pubmed
Response averages for the commonality of means used to teach a new procedure are as follows :
human cadaver ( 3.63 ; 3.46 - 3.80 ) , mannequin ( 2.70 ; 2.50 - 2.90 ) , living patient ( 2.09 ; 1.85 - 2.33 ) , and textbook ( 1.57 ; 1.32 - 1.82 ) . -
pubmed
MATERIALS AND METHODS : These women were diagnosed to have
PCOS by the European Society of
Human Reproduction and Embryology and the American Society of Reproductive Medicine , Rotterdam 2003 criteria . -
pubmed
The common indications for CLKT in
children are different from those of
adults and include
metabolic diseases affecting the kidney with or without
liver dysfunction and
congenital developmental abnormalities affecting both organs . -
pubmed
To investigate the mechanisms of
halothane - induced
liver injury , we used a recently established
mouse model of
liver injury . -
pubmed
Prophylactic immunization with AAV1 protected 100 % of the
mice from
tumor growth for more than 1 year , whereas all the control
mice immunized with either a LacZ vector or saline grew large
tumors and died within 6 weeks after inoculation of E7 - positive
tumor cell line
TC-1 . -
pubmed
In addition , therapeutic immunization with AAV1 after palpable
tumor formation inhibited
tumor growth and caused
tumor regression in some
mice . -
pubmed
Thus , our studies support the potential of
AAV vectors as a genetic vaccine for the prevention and treatment of
HPV - induced
malignancies . -
pubmed
Helicobacter pylori and
gastric cancer : a marital risk ? -
pubmed
Similarly , OLETF
rats consumed significantly more of higher concentration
corn oils than LETO while non - deprived sham feeding . -
pubmed
Conversely , OLETF
rats overconsumed low concentration
corn oil compared to LETO during overnight deprived sham - feeding tests . -
pubmed
Staphylococci ( both
Staphylococcus aureus and coagulase - negative
Staphylococcus ) have emerged as the most common cause of
PVE and are associated with a severe prognosis . -
pubmed
Systems for victim identification , arrangements for
human remains , management of dead bodies , evaluation of the different patterns of
injuries and , finally , detailed identification of the cause of
death all played an important role . -
pubmed
METHODS : We analyzed the transcriptome of
human LNCaP prostate cancer cells as they progress to
CRPC in vivo using replicate LongSAGE libraries . -
pubmed
cerevisiae ,
Streptococcus pneumoniae ( a pathogen responsible for
human pneumonia ) ,
Borrelia burgdorferi ( the pathogen that causes
Lyme disease ) , and
Plasmodium falciparum ( responsible for most
human malaria ) are reported . -
pubmed
OBJECTIVE : To investigate the effect of
atorvastatin therapy on
inflammation , disease activity ,
endothelial dysfunction , and arterial stiffness in
patients with
rheumatoid arthritis (
RA ) . -
pubmed
METHODS : This study included 30
patients with
early RA , randomly divided into 2 groups . -
pubmed
CONCLUSION :
Atorvastatin therapy in
patients with
RA reduced disease activity and conventional and novel vascular risk factors that promote the
atheromatous lesion . -
pubmed
A reduction of recipient regulatory T cells by
cyclophosphamide contributes to an anti -
tumor effect of nonmyeloablative allogeneic stem cell transplantation in
mice . -
pubmed
A donor lymphocyte infusion ( DLI ) in the
cyclophosphamide - induced tolerant
mice exerted strong anti -
tumor effects on an MBT-2 murine
bladder tumor , MBT-2 via their graft versus
tumor ( GVT ) activity . -
pubmed
The article presents the case of a 41 - year - old
patient with a
tumor of the distal third of left femur . -
pubmed
In view of the possibility of
NAHI ,
child protection investigations were initiated . -
pubmed
N - acetylcysteine (
NAC ) has been recently proposed as an adjuvant therapeutic drug for
influenza pneumonia in
humans . -
pubmed
This proposal is based on its ability to restrict
influenza virus replication in vitro and to attenuate the severity of the disease in
mouse models . -
pubmed
Although available studies were made with different viruses (
human and avian ) , published information related to the anti -
influenza spectrum of
NAC is scarce . -
pubmed
In this study , we show that
NAC is unable to alter the course of a fatal
influenza pneumonia caused by inoculation of a murinized
swine H1N1 influenza virus . -
pubmed
NAC was indeed able to inhibit the
swine virus in vitro but far less than reported for other
strains . -
pubmed
Zoledronic acid to prevent
bone loss in Chinese
men receiving
androgen deprivation therapy for
prostate cancer . -
pubmed
METHODS : Overall 26
prostate cancer patients with ADT were given
zoledronic acid 4 mg by a 15 - min i.v . -
pubmed
Seven
patients had
bone metastases . -
pubmed
Risk factors and outcomes for
patients with
vascular disease and serious
bleeding events . -
pubmed
OBJECTIVE : To determine the risk and outcomes of serious
bleeding events in
patients with
atherosclerotic vascular disease or risk factors . -
pubmed
METHODS : 68 375
outpatients with prior ischaemic vascular events or multiple
atherosclerotic risk factors were followed in this prospective observational study ; 64 977 had 1 - year follow - up data . -
pubmed
Main outcome measures were rates of serious
bleeding events and 1 - year outcomes for
patients with and without serious
bleeding events . -
pubmed
Patients with symptomatic
vascular disease had a
haemorrhage rate of 1.0 % , compared with 0.59 % in those with risk factors only . -
pubmed
METHODS : Retrospective claims data were analyzed for
hypertensive adults with & gt;=1 year follow - up from first ARB claim . -
pubmed
Response : Association between
Diabetic Polyneuropathy and Chronic Complications in
Type 2 Diabetic Patients ( Diabetes Metab J 2011;35:390 - 6 ) . -
pubmed
Statins have been successfully used in
patients with
hypercholesterolemia and
cardiovascular diseases , but there is increasing evidence that they exert effects by much exceeding the lowering of
cholesterol levels . -
pubmed
BACKGROUND : Locally advanced
breast cancer (
LABC ) is common in developing countries and it frequently affects younger
women . -
pubmed
CONCLUSIONS : despite the use of standard multi - modality approach in the management of
patients with
LABC , prognosis remains guarded . -
pubmed
RESULTS : New - confirmed
T2DM patients with the significantly abnormal statistic results about AIR3.5 and ISI , while NGT patients had the abnormal results compared with normal control group but better than
T2DM patients . -
pubmed
CONCLUSION : Compared with normal group
patients , NGT group appeared decrease of pancreases first phase secretes and
insulin resistance but not aggravate enough to induce
type 2 diabetes . -
pubmed
Prevalence and length of recovery of
pusher syndrome based on
cerebral hemispheric lesion side in
patients with
acute stroke . -
pubmed
METHODS : A total of 1660
patients with
acute stroke were investigated . -
pubmed
Risk ratios were used to evaluate the differences in the prevalence of
PB between right cerebral hemisphere - damaged (
RCD ) and left cerebral hemisphere - damaged (
LCD )
patients . -
pubmed
CONCLUSIONS : The number of
RCD patients who exhibited
PB was higher than that of
LCD patients . -
pubmed
Notably , impaired immunity in DR3(KO ) hosts on a C57BL/6 background was associated with 4- to 7 - fold increases in viral loads during the acute phase of
infection , and in
mice with suboptimal NK responses was essential for survival ( 37.5 % ) . -
pubmed
Does metabolic compensation explain the majority of less - than - expected
weight loss in
obese adults during a short - term severe diet and exercise intervention ? -
pubmed
DESIGN : In all , 16
obese men and women ( 41 + - 9 years ;
body mass index (
BMI ) 39 + - 6 kg m(-2 ) ) were investigated in energy balance before , after and twice during a 12 - week very - low - energy diet(565 - 650 kcal per day ) plus exercise ( aerobic plus resistance training ) intervention . -
pubmed
On the day of admission , the 24 - item Western Ontario and McMaster Universities
Arthritis Index ( WOMAC ) was used to evaluate each
patient 's
pain and functional capacity before surgery . -
pubmed
Of the 31
patients receiving
lidocaine patch 5 % , 94 % of the
patients reported satisfaction and attributed
pain relief to its use . -
pubmed
CONCLUSIONS : Overall , the concurrent use of
lidocaine patch 5 % in treating the
postoperative pain of
patients after TKA does not provide significant additional
pain relief compared with control subjects . -
pubmed
In addition ,
tumor pathology was able to divide not only the
patients as a whole ( p<0.001 ) , but also both
patients with stage IVa ( p=0.007 ) and IVb ( p=0.007 ) , into two groups for overall survival , respectively . -
pubmed
Tumor pathology is not only associated with the overall survival but is also able to divide both
patients as a whole and those sub - classified by stage , into two independent groups before surgery . -
pubmed
Transgenic resistance confers effective field level control of
bacterial spot disease in
tomato . -
pubmed
We investigated whether lines of transgenic
tomato (
Solanum lycopersicum ) expressing the Bs2 resistance gene from
pepper , a close relative of
tomato , demonstrate improved resistance to
bacterial spot disease caused by Xanthomonas species in replicated multi - year field trials under commercial type growing conditions . -
pubmed
Porphyromonas gingivalis is a major etiological agent in chronic and aggressive forms of
periodontal disease . -
pubmed
The transcriptome analysis confirmed the expression of all predicted ORFs for
strain ATCC 33277 , including 854 hypothetical proteins , and allowed the identification of hitherto unknown transcriptional units . -
pubmed
Acute demyelination in a
person with
amphetamine abuse . -
pubmed
We report the case of a 31 - year - old
woman , admitted to the hospital for
chest pain , dying a few days later from
septic multiorgan failure , and showing at autopsy foci of acute
demyelination in the occipital lobe . -
pubmed
This study investigates the role of oxidative damage causing
haemolysis as a possible factor contributing to reduced red blood cell survival and thereby to
renal anaemia in
patients on chronic haemodialysis . -
pubmed
MATERIAL AND METHODS :
Patients who tested positive for
H. - pubmed
We report a case of early
bioprosthetic valve calcification in a 76 year - old
woman who had received supplementation with
alfacalcidol , an analogue of
vitamin D , for 3 years after her initial valve replacement . -
pubmed
The antiherpetic efficacy of MI - S was assessed in
murine ocular , cutaneous , and genital infection models of HSV . -
pubmed
Topical application of MI - S on
skin lesions was also not effective , but cutaneously infected
mice treated orally with MI - S had significantly reduced disease scores ( P & lt ; 0.05 ) after day 9 , suggesting that healing was accelerated . -
pubmed
Patients presenting with synchronous or metachronous
colorectal cancer liver metastases (
CLM ) should be evaluated for multimodal management with curative intent . -
pubmed
Preoperative systemic chemotherapy shows beneficial impact on adjuvant progression - free survival and also borderline on overall survival , without significantly increasing initially R0 resectable
patients postoperative complication rates . -
pubmed
Antibiotics for
human toxoplasmosis : a systematic review of randomized trials . -
pubmed
The present study determined the impact of 5 Hz repetitive transcranial magnetic stimulation ( rTMS ) over the SMA on a fine motor movement , handwriting ( writing cursive " l"s ) , and on cortical excitability , in
individuals with
PD . -
pubmed
In a cross - over design , ten
individuals with
PD were randomized to receive either 5 Hz or control stimulation over the SMA . -
pubmed
Further , these data may provide the foundation for a larger investigation of the effects of noninvasive brain stimulation over the SMA in
individuals with
PD . -
pubmed
OBJECTIVE : To investigate the relationship between the clinical features , pathogenesis , immunophenotype , different classification models and prognosis in Chinese
patients with
diffuse large B - cell lymphoma (
DLBCL ) . -
pubmed
RESULTS : ( 1 ) Kaplan - Meier univariate analysis of the clinical data of 147
DLBCL patients found that the 3 - year overall survival ( OS ) rates were better in early stage ( P=0.032 ) , low IPI score ( P=0.001 ) , less than one extranodal involvement ( P=0.014 ) , and complete remission ( P<0.01 ) . -
pubmed
METHODS : A total of 28 eyes from 28
patients presenting with
primary open angle glaucoma who underwent NPDS were studied . -
pubmed
This is the first report of
congenital adrenal hyperplasia (
CAH ) due to combined
17alpha - hydroxylase / 17,20 lyase deficiency in an Omani
patient who was initially treated for many years as a case of
hypertension . -
pubmed
A 22 - year - old
woman who was diagnosed to have
hypertension since the age of 10 years who was treated with anti -
hypertensive therapy was referred to the National Diabetes and Endocrine Centre , Royal Hospital , Oman . -
pubmed
The
patient was treated with
dexamethasone and
ethinyl estradiol with cessation of anti -
hypertensive therapy . -
pubmed
BACKGROUND :
Patients with
mild cognitive impairment (
MCI ) have varying risks of progression to
Alzheimer ' s disease (
AD ) . -
pubmed
METHODS : 119 blood plasma samples of
patients with
MCI with different outcomes ( stable
MCI and progressive
MCI ) were analyzed by untargeted , label - free shotgun proteomics . -
pubmed
Early results of anterior elbow release with and without biceps lengthening in
patients with
cerebral palsy . -
pubmed
PURPOSE : To investigate the effect of partial biceps lengthening on elbow flexion posture and active elbow flexion and extension in
patients with
cerebral palsy . -
pubmed
METHODS : We retrospectively reviewed 29
patients with
cerebral palsy who underwent anterior elbow release as part of multilevel upper extremity surgery . -
pubmed
CONCLUSIONS : Early results of partial lengthening of the biceps tendon showed that it may improve elbow flexion posture and active elbow extension in
patients with
flexion deformity in
cerebral palsy . -
pubmed
The PHMD method detected 96.6 % IC events in
THA patients and 99.1 % in
CPP patients with an average error of 5.3 ms and 18.4 ms . -
pubmed
The HPA method detected 99.1 % IC events in
THA patients and 97.3 % IC events in
CPP patients , with an average error of 57.5 ms and 10.2 ms . -
pubmed
Children with
intractable epilepsy benefit from early surgical treatment when possible to reduce long - term morbidity . -
pubmed
OBSERVATION : We report a case series of 3
patients with
ACG that developed on long - haul flights . -
pubmed
CONCLUSION AND RELEVANCE :
Individuals with risk factors should be advised on the symptoms of
ACG and the appropriate course of action should those symptoms occur . -
pubmed
CASE DESCRIPTION : The authors present a case of a 47 - year - old
female who presented with clinical features mimicking an acute
spinal disorder but later found to have an adhesive
arachnoiditis . -
pubmed
To examine the association between markers of macromolecular oxidative damage and risk of
NTDs , we measured levels of
8 - hydroxy-2 '- deoxyguanosine (
8 - OHdG ) , protein
carbonyl ( PC ) , and
8 - iso - prostaglandin F2alpha (
8 - iso - PGF2alpha ) in maternal serum samples of 117
women with
NTD - affected pregnancies and 121
women with healthy term newborns . -
pubmed
METHODS : For 96
A / H3N2 virus isolates the 50 % inhibitory concentration ( IC50 ) ( 48 each from the 2011 - 12 and 12 - 13
influenza seasons ) was measured . -
pubmed
Isovaline attenuates generalized
epileptiform activity in hippocampal and primary sensory cortices and
seizure behavior in
pilocarpine treated
rats . -
pubmed
However , 30 % of
patients with
epilepsy are not adequately treated with anti -
seizure medications and are considered intractable . -
pubmed
Isovaline also attenuated hippocampal
epileptiform activity and behavioral
seizures in vivo in
rats administered
4 aminopyridine (
4AP ) . -
pubmed
Here , we investigate whether
isovaline is efficacious in attenuating secondarily generalized
epileptiform activity and behavioral
seizures in
rats administered
pilocarpine . -
pubmed
The mosquito ,
Culex pipiens pallens ( L. ) , is an important vector of
encephalitis and
filariasis in northern China . -
pubmed
A 61 - year - old
woman presented with
thigh pain and
gait disturbance due to
weakness in her lower right extremity . -
pubmed
Immediately after surgery , the
patient 's thigh
pain resolved and she remained stable with normal vital signs . -
pubmed
The
patient was discharged 14 days after surgery without leg
pain or any respiratory problems . -
pubmed
Ectopic
Schistosoma mansoni Eggs Inside a
Lipoma . -
pubmed
This report presents the first described case of ectopic
Schistosoma mansoni eggs inside a subcutaneous
lipoma far from the tissues of this worm 's life cycle and with no connection to either portal veins or any other vascular system . -
pubmed
We describe the case of a 25 year old
man following bariatric surgery who increased his ingestion of
ondansetron , taking up to 40 tablets / day due to
excessive nausea and vomiting . -
pubmed
The
patient was hospitalized for progressively more severe
headache of 1 week 's duration . -
pubmed
Three days into his admission , following improvement in his BP with oral anti -
hypertensive but continued use of the
ondansetron , the
patient developed near complete
blindness . -
pubmed
Bioaccumulation , oxidative stress and
genotoxicity in fish (
Channa punctatus ) exposed to a thermal power plant effluent . -
pubmed
STUDY DESIGN : Eligible
infants aged & lt;=4 months presenting to the main pediatric emergency service with
apnea associated
bronchiolitis were stratified by gestational age ( & lt;34 weeks or longer ) and randomized to receive a single dose of intravenous 25 mg / kg
caffeine citrate or saline placebo . -
pubmed
RESULTS : A total of 90
infants diagnosed with
viral bronchiolitis associated with
apnea ( median age , 38 days ) were enrolled . -
pubmed
The recent advances in the study of the
human papillomavirus ( HPV ) infection ( the necessary cause for CxCa development ) have guided clinical practice to add
HPV related tests alongside the Pap test . -
pubmed
METHODS : From May to November in 2014 , anonymous questionnaires were distributed to adult
CML patients who were receiving TKI treatment all over China . -
pubmed
Association between
desloratadine and
prednisolone in the treatment of
children with acute symptoms of
allergic rhinitis : a double - blind , randomized and controlled clinical trial . -
pubmed
OBJECTIVE : To evaluate safety and efficacy of
desloratadine plus
prednisolone in the treatment of acute symptoms of
children ( 2 - 12 years ) with
allergic rhinitis , and to compare it to
dexchlorpheniramine plus
betamethasone . -
pubmed
METHODS :
Children with moderate / severe persistent
allergic rhinitis and symptomatic ( nasal symptoms score [ 0 - 12]>=6 ) were allocated in a double - blind , randomized fashion to receive
dexchlorpheniramine plus
betamethasone ( n=105 ; three daily doses ) or
desloratadine plus
prednisolone ( n=105 ; single dose followed by two of placebo ) for 7 days . -
pubmed
CONCLUSION : The
desloratadine plus
prednisolone combination was able to effectively control acute symptoms of
rhinitis in
children , improving symptoms and nasal function . -
pubmed
The
18F - labeled compounds were evaluated in
nude mice bearing
LNCaP tumors and compared to
[ 68Ga ] Ga - PSMA - HBED - CC and
[ 18F ] DCFPyL. -
pubmed
Microcystic macular edema in a case of
tobacco -
alcohol optic neuropathy . -
pubmed
Ten pediatric
patients who underwent
ventricular tachycardia ablation were transferred immediately postablation to a 1.5 T MRI scanner and late
gadolinium enhancement ( LGE ) imaging was performed to characterize ablation lesions . -
pubmed
All
patients underwent radiofrequency catheter ablation of
ventricular arrhythmia with acute procedural success . -
pubmed
LGE was identified at the reported ablation site in 9/10
patients , all
arrhythmia - free at median 7 months follow - up . -
pubmed
We examine host - associated variation in larval performance ( survivorship , development time , and adult
body weight ) and oviposition preference , within and between two populations
ofStator limbatus ( Coleoptera : Bruchidae ) that differ in the hosts available to them in nature . -
pubmed
Sleep disorders require a comprehensive evaluation and confirmation with polysomnography in
patients with
multiple sclerosis . -
pubmed
The prognosis of
patients with
WD is excellent , especially for those without
cirrhosis at the time of diagnosis , but requires timely initiation of appropriate therapy specific for
WD and for the
patient 's
liver disease independent of
WD . -
pubmed
However , they also focused on the preictal stage of
NO - triggered and native
human migraine attacks and suggested a predominant role of the hypothalamus shortly before the beginning of
migraine headaches as well as alterations in hypothalamic functional connectivity . -
pubmed
Results showed that
ethanol feeding exacerbates the progression of
hepatic tumors ( characterized by the ratio of liver weight to
body weight , and the
tumor volume and diameter ) in
DEN - treated
mice . -
pubmed
METHODS : In
AD patients and controls the expression of enzymes involved in the biosynthesis of FFAs and CERs was analyzed in relation to the SC lipid composition . -
pubmed
In TH2 treated
human skin equivalents (
AD HSEs ) mimicking lesional
AD skin , the mRNA expression of these enzymes was investigated . -
pubmed
For
patients who underwent internal suspension technique , the surgeons preserved the external fat of the
renal tumor as a suspension traction measure when separating the kidney . -
pubmed
Patients with
obesity are more prone to experience opioid - related adverse events ( ORAE ) . -
pubmed
OBJECTIVES : The objective of this study is to determine if a multimodal analgesia protocol ( MAP ) reduces ORAE and provides effective
pain relief for
patients after LSG . -
pubmed
CONCLUSION : Our study suggests that a MAP reduces ORAE and provides effective
pain relief for
patients undergoing LSG . -
pubmed
DIAGNOSIS AND SUCCESSFUL TREATMENT OF A POTENTIALLY ZOONOTIC
DERMATOPHYTOSIS CAUSED BY
MICROSPORUM GYPSEUM IN A ZOO - HOUSED NORTH AMERICAN PORCUPINE ( ERETHIZON DORSATUM ) . -
pubmed
A female North
American porcupine (
Erethizon dorsatum ) was evaluated for a unilateral pedal
crusting and
alopecic dermatopathy . -
pubmed
Fungal culture and histopathology testing revealed
Microsporum gypseum dermatophytosis . -
pubmed
We report a case of
GPPD in an elderly white
man who had an eruption involving the majority of the lower legs . -
pubmed
In this study we used a
mouse model of
neuropathic pain to dissociate these factors . -
pubmed
We performed RNA - seq on purified peripheral afferent neurons , but found no striking differences in gene expression between male and female
mice , neither before nor after
nerve injury . -
pubmed
The majority of the screened compounds displayed potent anticancer activity against both
HCT116 and
HepG2 human cancer cell lines . -
pubmed
Complex three - dimensional ( 3D ) in vitro models that recapitulate
human tumor biology are essential to understand the pathophysiology of the disease and to aid in the discovery of novel anti -
cancer therapies . -
pubmed
In the future , 3D cultures will be instrumental for understanding the mode of action of drugs , identifying genotype - drug response relationships and developing
patient - specific and personalized
cancer treatments . -
pubmed
Patients with biochemically and histologically proven
papillary thyroid cancer (
PTC ) and
ATC were included . -
pubmed
Tumor - bearing
mice ( 10 / group ) were administered 10 mg / kg
lenvatinib ( p.o . ) -
pubmed
Gene expression in
patient - derived
PTC and
ATC cells was compared using a microarray approach . -
pubmed
Tumor volume and cell properties were examined in the
mouse xenograft model . -
pubmed
PARTICIPANTS :
Individuals aged 65 and older treated with
DAA therapy for
hepatitis C virus (
HCV ) during the study period ( N=113 ) divided into 2 cohorts : aged 65 to 74 ( n=88 ) and aged 75 and older ( n=25 ) . -
pubmed
CONCLUSION :
DAA therapy is highly efficacious for the treatment of
HCV in older adults , but those aged 75 and older are more likely to have clinically significant pretreatment DDIs and experience AEs , including
ribavirin - induced
anemia , during therapy . -
pubmed
To study this issue , we created a decision - model comparing proton vs. X - ray radiotherapy for locally advanced
non - small cell lung cancer patients . -
pubmed
For
patients treated with IMRT experiencing grade 4
pneumonitis or grade 4
esophagitis , costs exceeded patients treated with protons without this
toxicity . -
pubmed
3DCRT
patients with grade 4
esophagitis had higher costs than proton
patients without this
toxicity . -
pubmed
In our continuing search for anticancer agents from higher plants , a
chloroform extract of the leaves and twigs of
Syzygium corticosum collected in Vietnam was found to be active toward the
HT-29 human
colon cancer cell line . -
pubmed
Two - hundred and ninety
patients with
MVD and/or UPLMD who were treated consecutively with percutaneous coronary intervention ( PCI ) were included in the present study . -
pubmed
Results : Of 227
patients with open emergency appendectomy for complicated
appendicitis , 114 had received abdominal drain after the surgery . -
pubmed
Local Anesthetic Wound Infiltration after Osteosynthesis of Extracapsular
Hip Fracture Does Not Reduce
Pain or Opioid Requirements : A Randomized , Placebo - Controlled , Double - Blind Clinical Trial in 49
Patients . -
pubmed
The
patients received intraoperative infiltration followed by 6 postoperative injections through a
wound catheter in eight - hour intervals . -
pubmed
A wide variability of motor phenotype has been observed in the different
murine models of
AD , without a consistent correlation with the extent of cerebellar histopathological changes or with
cognitive deficits . -
pubmed
The loss of noradrenergic drive may contribute to the
impairment of cerebellar synaptic function and motor learning observed in these
mice . -
pubmed
Methods : The study enrolled 100
patients with
peripheral arterial disease (
PAD ) and 100
patients with
RA . -
pubmed
Here we report the molecular characterisation of a novel dsRNA virus isolated from the filamentous , plant pathogenic fungus
Leptosphaeria biglobosa and known to cause significant alterations to fungal pigmentation and growth and to result in hypervirulence , as illustrated by comparisons between virus - infected and -cured isogenic fungal
strains . -
pubmed
In clinical
patients , enlarged LA was associated with older age ,
atrial fibrillation ,
hypertension ,
heart failure , inpatient status and
biventricular dilatation . -
pubmed
The use of TDM offers the possibility of a more personalized treatment approach for
patients with
IBD . -
pubmed
Compared with ViVc , ViVr
patients presented twice as early after surgical heart valve ( SHV ) implantation ( 55.2 + -36.1 vs. 118.4 + -57.7 months , p<0.001 ) , were more commonly female ( 82.8 % vs. 41.3 % , p<0.001 ) , and had shorter body stature and reduced
body weight ( p<0.05 for both ) prior to PS . -
pubmed
T - bet+ B cells have emerged as a key component of the humoral immune response in both
infections and
autoimmune disorders , with many of their phenotypic and functional attributes conserved between
mice and
humans . -
pubmed
METHODS : Long - term 5 - year MacNab outcomes , visual analogue scale ( VAS ) scores , complications , and unintended aftercare were analyzed in a series of 86
patients who underwent endoscopic transforaminal foraminoplasty for
foraminal stenosis . -
pubmed
Postoperative
dysesthesia occurred in 9
patients . -
pubmed
Another 9
patients had recurrent
disc herniations ( 10.5 % ) . -
pubmed
Failure to cure with persistent
pain occurred in 3
patients . -
pubmed
Two
patients developed
pain postoperatively stemming from a different level . -
pubmed
One
patient experienced a postoperative
hematoma which ultimately was inconsequential and did not require any additional surgery . -
pubmed
CONCLUSION :
Patients with symptomatic
foraminal stenosis may be treated successfully with early transforaminal endoscopic decompression while maintaining favorable long - term outcomes without the need for fusion in the vast majority of
patients . -
pubmed
Salmonella ,
Staphylococcus aureus ,
Clostridium perfringens and
Bacillus cereus were the main bacteriological agents to cause illness , but there were far fewer incidents of
salmonellosis in 1981 ( 36 ) compared with 1980 ( 64 ) . -
pubmed
Eight incidents of
waterborne disease , caused by
Giardia lamblia , Campylobacter ,
Salmonella ,
Pseudomonas aeruginosa and an undetermined agent , are double the number recorded for both 1980 and 1979 . -
pubmed
Given that herpesviruses are arguably the most prevalent opportunistic pathogens and often reactivate in the elderly , it is reasonable to argue reactivation of herpesviruses might be major culprits for initiating
AD in
individuals carrying
AD susceptibility genes . -
pubmed
The Eunice Kennedy Shriver National Institute of Child Health and
Human Development , in collaboration with the National Heart , Lung , and Blood Institute and the US Food and Drug Administration , sponsored a workshop of experts to discuss the current state of childhood primary
hypertension . -
pubmed
We investigated the spatiotemporal deterioration patterns of brain structures in
patients with
subcortical infarction and identified the regions that contributed to
verbal memory impairment . -
pubmed
Cognitive assessment and structural magnetic resonance imaging were performed 1 , 4 , and 12 weeks after
stroke onset in 28 left - hemisphere and 22 right - hemisphere
stroke patients with
subcortical infarction . -
pubmed
Practitioner Summary :
Confusion arising from look - alike drug names may compromise
patient safety . -
pubmed
Abstract : The ketogenic diet ( KD ) is a high - fat and very low - carb diet , which has been used primarily for treatment of therapy - resistant
epilepsy in
children . -
pubmed
Nevertheless , study results are too heterogenic for a general recommendation of the
KD in this
patient population . -
pubmed
Drug - coated balloon for treatment of de - novo
coronary artery lesions in
patients with high
bleeding risk ( DEBUT ): a single - blind , randomised , non - inferiority trial . -
pubmed
BACKGROUND : The optimal technique of percutaneous coronary intervention in
patients at high
bleeding risk is not known . -
pubmed
Patients were eligible if they had an ischaemic de - novo lesion in a coronary artery or bypass graft that could be treated with drug - coated balloons , at least one risk factor for
bleeding , and a reference vessel diameter of 2 5 - 4 0 mm . -
pubmed
INTERPRETATIONS : Percutaneous coronary intervention with drug - coated balloon was superior to bare - metal stents in
patients at
bleeding risk . -
pubmed
GETV infection in
horses has been reported in Japan and India , and causes great economic losses . -
pubmed
Blood samples were collected from the sick
horse , and PCR / RT - PCR analysis was performed to screen for equine viral pathogens associated with
fever . -
pubmed
Phylogenetic analysis indicated that GZ201808 clustered in Group III , and was located in an independent branch distant from other
horse - derived GETV
strains , indicating a unique evolutionary pattern of GZ201808 . -
pubmed
This study first determined and described the disease course of
horse infected with
GETV in China , sequenced and characterized the genome of the field
horse - derived GETV
strain , and therefore presented an unequivocal report of
GETV infection in
horses in China . -
pubmed
RESULTS : R6/1
mice were deficient in instinctive and
anxiety related behaviors as well as long - term memory capabilities . -
pubmed
Subgroup analysis found that ORs of studies in hemodialysis patients ( OR = 4.89 , 95 % CI 2.54 - 9.90 , p < .001 ) and
acute ischemic stroke patients ( OR = 1.60 , 95 % CI 1.14 - 2.25 , p = .007 ) were higher than general population ( OR = 1.15 , 95 % CI 1.03 - 1.29 , p = .01 ) . -
pubmed
Should We Investigate
Osteoarticular Infections for
Kingella kingae in Older - than - expected Immunocompetent Children ? -
pubmed
Results : A 49 - year old Caucasian
man with a family history of
retinitis pigmentosa , presented with
low vision and
night blindness from early childhood . -
pubmed
Evaluation of morphokinetic characteristics of
zona pellucida free
mouse pre - implantation embryos using time - lapse monitoring system . -
pubmed
METHODS : Eleven
patients with
systemic amyloidosis were reviewed retrospectively . -
pubmed
RESULTS : On ICGA , all
patients exhibited hyperfluorescent
spots in the late stage and were classified according to pre - existing criteria . -
pubmed
BACKGROUND :
Patients with
malnutrition have a high risk of
postoperative complications in total knee arthroplasty ( TKA ) . -
pubmed
The rtM204I / sW196 * transformants , compared with the control or wild type , showed enhanced transactivation activities for c - fos , increased cell proliferation , decreased apoptosis , more anchorage - independent growth , and enhanced
tumor growth in
mouse xenografts . -
pubmed
GSDIa patients are characterized by
hypoglycemia ,
hepatomegaly ,
hyperlipidemia , and
hyperlactacidemia . -
pubmed
PATIENTS AND METHODS : Clinical data on
GSDIa patients ' characteristics were collected . -
pubmed
RESULTS : A total of 163
GSDIa patients were enrolled in this study . -
pubmed
Effect of intentional restriction of venous return on tissue oxygenation in a
porcine model of
acute limb ischemia . -
pubmed
We investigated whether partial
venous occlusion in the common iliac vein ( CIV ) causes a further increase of venous oxygenation in a
porcine model of acute
hindlimb ischemia . -
pubmed
Progesterone treatment does not decrease serum levels of biomarkers of
glial and neuronal cell injury in moderate and severe
TBI subjects : A secondary analysis of the
Progesterone for
Traumatic Brain Injury , Experimental Clinical Treatment ( ProTECT ) III trial . -
pubmed
EV demonstrates a favorable profile in heavily pretreated
patients with locally advanced or metastatic
urothelial carcinoma . -
pubmed
[ Correlations between
alpha 1 - antitrypsin deficiency and some exogenous risk factors in
patients with
chronic obstructive bronchopneumopathy ] . -
pubmed
Three beta1 - selective beta - blocker (
metoprolol ,
practolol and
H 87 / 07 ) were compared in 29
patients with stable
angina pectoris . -
pubmed
Except for one
patient who experienced a severe
exanthema on
practolol , the three beta - blockers were equally well tolerated . -
pubmed
Also the clinical condition of
thyrotoxicosis appeared to be correlated with FT3 concentrations ( toxic
patients , group as a whole : 9.6 + /- 4.0 pg / ml ; euthyroid
patients : 6.8 + /- 3.1 ; toxic
patients with normal values of T3 and T4 ; 8.3 + /- 2.8 ) . -
pubmed
Experimental
right ventricular hypertrophy and failure in
swine . -
pubmed
Following pulmonary arterial constriction , 22
pigs developed
right ventricular failure and 10
right ventricular hypertrophy . -
pubmed
Comparing results with those obtained in 21 normal
pigs ( no pulmonary artery constriction ) , it was found the right ventricular peak systolic and end -
diastolic pressures , cardiac output , and right ventricular weight distinguished
hypertrophied and failing hearts from normal ones . -
pubmed
coli
strains and with
mice LS fibroblasts in vitro . -
pubmed
[
Idiopathic thrombocytopenic purpura in
children and in adults . -
pubmed
To further examine whether the acquisition of the two ts-1[E ] lesions will predictably attenuate new
influenza A variants , the
HK / 68 - ts-1[E ] virus was mated with the
A / Vic / 3 / 75 wild - type virus . -
pubmed
Steatocystoma multiplex in a
dog . -
pubmed
DNA was extracted from isolates of bacteriophages grown on virulent and avirulent
strains of
Agrobacterium tumefaciens . -
pubmed
12
patients with
pain in the piso - triquetral region are described . -
pubmed
[ Silent
ischemic heart diseases in
patients with
peripheral arterial diseases . -
pubmed
Silent
ischaemic heart disease was looked for by exercise stress testing in 418
patients with chronic obliterative
arterial disease of the lower limbs with no clinical or electrocardiographic signs of
myocardial ischaemia . -
pubmed
Patients who had a positive exercise stress test initially had a particularly high
death rate ( 23 % ) and developed clinical signs of
coronary insufficiency in 57.5 % of cases . -
pubmed
Silent
ischaemic heart disease is very prevalent in
patients with
obliterative arterial disease of the lower limbs and is a main vital prognostic factor in these patients . -
pubmed
These results confirm the need for a complete cardiovascular check - up in all
patients with
peripheral arterial disease . -
pubmed
Aluminium production plant workers are exposed to a great number of airborne
polycyclic aromatic hydrocarbons and epidemiological studies suggest that these
workers are at increased risk of
lung and bladder cancer . -
pubmed
A total of 254
patients with a history of two or more
duodenal ulcers , the most recent event diagnosed within three months of study entry , were entered into the trial after healing was documented . -
pubmed
Patients received
sucralfate 1 g twice daily or placebo for four months , or until
recurrence . -
pubmed
At four months , there were 49
recurrences among 122
patients in the
sucralfate group and 71 among 117
patients for the placebo group . -
pubmed
At four months , there were 38
recurrences among 114
patients in the
sucralfate group and 54 among 104
patients for the placebo group . -
pubmed
Rupture of the spleen occurred in two
patients ( a
man of 32 and a girl of 16 years ) with serologically proven
infectious mononucleosis . -
pubmed
Ceftazidime was tested against 2,224
strains of
Pseudomonas aeruginosa obtained from 17 hospitals in April , May and June , 1986 and against 607
strains of
Klebsiella pneumoniae and 234
strains of
K. - pubmed
Comparison of these results with those of studies performed in 1984 and 1985 showed a moderate increase in the number of intermediate sensitivity
strains of
P. - pubmed
[
African horse sickness in Senegal : the state of natural and/or acquired immunity in
horses in a recent foci ] . -
pubmed
Adenocarcinoma from
endometriosis causing
urinary tract obstruction in a
patient on
oestrogen replacement therapy after hysterectomy . -
pubmed
A
patient on
oestrogen replacement therapy after hysterectomy developed
endometriosis and
adenocarcinoma . -
pubmed
ST - T isointegral analysis of exercise stress body surface mapping for identifying ischemic areas in
patients with
angina pectoris . -
pubmed
In 28
patients with
angina pectoris and 10 healthy subjects , body surface potential was recorded with 87 leads , and ST isopotential and ST - T isointegral maps were constructed . -
pubmed
In 23 of 28
patients with
angina pectoris ( 82 % ) , alterations in the ST - T isointegral map after exercise were observed . -
pubmed
In five
patients ( 18 % ) who did not show abnormalities on the postexercise ST - T isointegral map , the magnitude of maximal ST
depression was significantly smaller than that observed in the other 23
patients with
angina pectoris ( 0.14 vs 0.23 mV on the average , p less than 0.05 ) . -
pubmed
Combined live and inactivated
poliovirus vaccine to control
poliomyelitis in a developing country -- five years after . -
pubmed
In
patients older than 65 years operated on for
senile cataracts , the male - to - female ratio was 1.8 with a female predominance . -
pubmed
The mutagenic potency of each dye has been assessed by the
Salmonella typhimurium /
mammalian microsomal
mutagenicity assay utilizing the
TA100 and TA98 stains . -
pubmed
Virulence and serum resistance of
strain PAO1 were restored by curing of the entire plasmid R68.45 but not by deletions in the plasmid 's transfer gene regions . -
pubmed
Effects of various agents on
prednisolone - induced
gastric lesions in
rats . -
pubmed
We studied the effects of various agents on
prednisolone - induced
gastric lesions in
rats . -
pubmed
Gastric lesions were produced by subcutaneous administration of 50 mg / kg of
prednisolone once daily for 4 days to non - fasted
rats . -
pubmed
Among 50 geriatric
inpatients ( average age 79 ) with late - onset
epilepsy ( average duration two years ) , 28 had
grand mal attacks , 12 had focal attacks , seven had both . -
pubmed
The
epilepsy followed
cerebrovascular disease ( usually with
hemiplegia ) in 21
patients ( 8 per cent of all our
patients with
hemiplegia in the two - year study period developed
epilepsy ) . -
pubmed
[ Electrocardiographic changes in
patients with
atherosclerotic psychoses treated with
benzohexonium ] . -
pubmed
Data are also reported of a clinico - statistical study on the frequency of side - effects with
measles vaccination as well as of antibody response to it in 1542
children subdivided into different groups according to age and virus
strain used ( Schwarz or Moraten ) . -
pubmed
A
patient from the Caribbean area with
active T - cell lymphoma -
leukaemia was primarily treated with
deoxycoformycin (
DCF ) , 5 mg / m2 i.v . -
pubmed
T - cell lymphoma -
leukaemia has a bad prognosis with conventional anti -
lymphoma therapy but was exquisitely sensitive to
DCF in this
patient . -
pubmed
The histochemical characteristics of spontaneous
hepatocellular neoplasms in
mice of both sexes were examined and compared with those of
hepatocellular neoplasms induced in female
mice by administration of
polycyclic aromatic hydrocarbon carcinogens as initiators with or without subsequent
phenobarbitone treatment . -
pubmed
Spontaneous
neoplasms in the livers of
mice rendered
siderotic by subcutaneous
iron injection were deficient in cellular accumulation of stainable
iron . -
pubmed
It is concluded that the histochemical characteristics of spontaneous or induced
mouse hepatocellular neoplasms are variable and may be influenced by the inducing factors . -
pubmed
Site of the
ganglion blocking action of
gardneramine and
hirsutine in the
dog urinary bladder in situ preparation . -
pubmed
In both
strains of
rats immobilization stress induced a 2.3 - 3.3 - fold increase of PRA regardless of whether the
animals had intact superior cervical ganglia . -
pubmed
In both
strains of
rats SCGx resulted in depressed circulating
aldosterone levels at all studied times after surgery . -
pubmed
Thirteen
patients with either
Addison ' s disease , or
Cushing ' s disease treated by bilateral adrenalectomy , were infused with the long - acting met -
enkephalin analogue
DAMME . -
pubmed
Fifty - five
patients , 28 male and 27 female , with
congenital constriction band syndrome were reviewed . -
pubmed
In the secondary prevention , it reduces the further incidence of
sudden death in
patients in whom administration is started in relatively small doses within a few weeks after
acute myocardial infarction . -
pubmed
[ Mechanism of the development of functional
hyperemia in the palatal salivary glands of the
rat ] . -
pubmed
Thirty - eight
patients with advanced or recurrent
epithelial ovarian cancer no longer amenable to management with surgery , radiotherapy , or chemotherapy with known activity were given
piperazinedione 9 mg / m2 intravenously every 3 weeks . -
pubmed
Adverse effects consisted primarily of
myelosuppression ( 81 % ) ,
nausea and
vomiting ( 32 % ) , and
azotemia ( 29 % ) with three
patients ( 10 % ) having life - threatening
thrombocytopenia . -
pubmed
Ten randomly selected
adults who had undergone orthodontic treatment and isolated superior repositioning of the maxilla for
vertical maxillary excess ( VME ) were evaluated clinically and radiographically ( mean , 48.7 months postsurgery ) for
signs and symptoms of
masticatory and temporomandibular joint dysfunction . -
pubmed
All
patients were free of temporomandibular joint and
masticatory muscle pain during function , upon contralateral masticatory loading , and upon palpation . -
pubmed
In a double blind trial 60
patients were treated with a
salicylic acid - containing product against
warts ( Verrumal ) on basis
fluorouracil in comparison to placebo . -
pubmed
Chicken myoblasts were cultured from the pectoralis muscles of
dystrophic and normal 11 - day - old embryos . -
pubmed
Effects of
cromakalim or
glibenclamide on
arrhythmias and dispersion of refractoriness in chronically infarcted in anesthetized
dogs . -
pubmed
Dogs were anaesthetised , subjected to an anterior - apical
myocardial infarction , and allowed to recover . -
pubmed
Only
animals that did not have programmed electrical stimulation - inducible
arrhythmias were used . -
pubmed
Multinucleate cell angiohistiocytoma mainly affects middle - aged
women , and usually presents as grouped reddish - brown papules . -
pubmed
We report the successful use of the argon laser to treat two
patients who had
multinucleate cell angiohistiocytoma . -
pubmed
We investigated the formation of a "
nonthyroidal illness " (
NTI ) in
pigs undergoing
ventricular fibrillation (
VF ) and resuscitation . -
pubmed
To increase awareness of this medically treatable condition , we present two
patients who developed
SMAS after sustaining severe
brain injury . -
pubmed
Arteriojugular
oxygen difference ( AJDO2 ) is used to manage the care of
acute head - injured patients by monitoring the relationship between cerebral metabolism and blood flow . -
pubmed
The assay detected circulating antigen in 36 of 53 sera from
Chinese schistosomiasis japonica patients , but not in sera from healthy persons or patients with
paragonimiasis ,
trichinosis or
cysticercosis . -
pubmed
Aspirin toxicity in
chicks given diets deficient in
linoleic acid . -
pubmed
In
chicks fed LA - free diets , the ratio of 20:3n-9/20 : 4n-6 , which was used as an indicator of
LA deficiency , was suppressed by
aspirin treatment . -
pubmed
In experiment 1 ,
horses were brought in from pasture 3 weeks before administration of 1 injection of TA ( 0.09 mg / kg of
body weight , IM ) , and were stabled in dusty conditions throughout the experimental period . -
pubmed
Seventy three
patients with
biliary tract obstruction due to a primary
malignant tumor ( n = 60 ) , lymph node
metastases at the porta hepatis ( n = 10 ) and benign
stenosis of a biliary - enteric anastomosis ( n = 3 ) , were treated between 1985 and 1990 . -
pubmed
Mortality was 30 % at 30 days in the group of
patients with
malignant diseases . -
pubmed
To ascertain the prevalence and types of
arrhythmias occurring after heart transplantation in
children , all available 24 - hour ambulatory ECGs ( mean , 1.5 / patient ) , and 12 - lead surface ECGs ( mean , 27 / patient ) obtained from 59 orthotopic pediatric heart transplant recipients ( mean age , 9.7 + /- 5.9 years ) were examined . -
pubmed
Of the 59
patients , 24 ( 41 % ) were found to have
arrhythmias including
chronic sinus tachycardia ( eight
patients ) ,
sinus bradycardia ( four
patients ) ,
supraventricular tachyarrhythmias ( nine
patients ) , significant
ventricular premature depolarization ( seven
patients ) , and nonsustained
ventricular tachyarrhythmias ( seven
patients ) . -
pubmed
Graft survival was significantly lower in those
patients with
arrhythmias as compared with the
arrhythmia - free group ( 58 % versus 86 % , p = 0.02 ) . -
pubmed
Interaction between the effects of
5 - hydroxytryptamine and
adrenaline on the growth of platelet
thrombi in the coronary artery of the anaesthetized
dog . -
pubmed
The interaction between
adrenaline and
5 - hydroxytryptamine (
5 - HT ) has been quantitated on the rate of
thrombus formation , in the stenosed coronary artery with damaged endothelium of the anaesthetized
dog . -
pubmed
PURPOSE : The purpose of this study was to develop and validate an instrument for clinical trials to measure radiation - related acute morbidity and quality of life from the perspective of
patients with
head and neck cancer (
HNC ) treated with radiotherapy . -
pubmed
METHODS : The Head and Neck Radiotherapy Questionnaire ( HNRQ ) was developed by a panel of health care workers and
patients , was pretested in a pilot study of
HNC patients , and was validated in a randomized double - blind trial of concomitant
fluorouracil (
FUra ) infusional therapy ( 1.2 g / m2 per 24 hours ) or saline placebo administered for 72 hours in the first and third weeks of a 6 1/2 - week course of radiation therapy . -
pubmed
CONCLUSION : The HNRQ is a valid measure of acute morbidity due to radiation therapy in
patients with locally advanced
HNC , and may be useful as an outcome measure for future clinical trials of radiation treatment strategies . -
pubmed
Glutathione supplements protect preterm
rabbits from oxidative
lung injury . -
pubmed
Animals assigned to
oxygen had decreased lung volumes at 35 cmH2O , decreased lung compliance , increased
edema , decreased cell viability , and decreased lung tissue and lavage - reduced / oxidized
GSH levels , compared with control animals . -
pubmed
These studies suggest that
GSH supplementation maintains normal lavage and lung tissue
GSH levels in preterm
animals exposed to
hyperoxia and attenuates the changes in lung mechanics associated with
oxygen - induced
lung injury . -
pubmed
The metabolism of
riboflavin in female
patients with
liver cirrhosis . -
pubmed
The metabolism of
vitamin B2 was studied in five female
patients with
liver cirrhosis of varying etiology . -
pubmed
In conclusion ,
patients with
liver cirrhosis of varying etiology and varying medical treatment did not show alterations of
riboflavin turnover . -
pubmed
Our experience in four
patients operated on for
metastases or different primary
tumors demonstrated that this frontal approach may be safely used and allows minimal manipulation of the
tumor . -
pubmed
MRI of primary
meningeal sarcomas in two
children : differential diagnostic considerations . -
pubmed
Meningeal sarcomas are very rare , highly aggressive
tumours affecting
children more frequently than adults . -
pubmed
Glutamine and
arginine metabolism in
tumor - bearing
rats receiving total parenteral nutrition . -
pubmed
Since
glutamine production is increased in catabolic states , these observations prompted us to investigate whether the flux of
arginine to
glutamine was increased in
tumor - bearing ( TB )
rats , and we measured the synthesis rate of
glutamine from
arginine in control versus
TB rats receiving standard total parenteral nutrition ( TPN ) solution . -
pubmed
Male
Donryu rats ( N = 36 ;
body weight , 200 to 225 g ) were divided into two groups , control and TB
rats . -
pubmed
Yoshida
sarcoma cells ( 1 x 10(6 ) ) were inoculated into the back of the
rats ( n = 18 ) subcutaneously on day 0 . -
pubmed
An increase in the flux rate of
Arg to
Gln was associated with an enhancement in the ratio of specific activity of
ornithine to specific activity of
arginine in
TB rats ( control 51.5 % + /- 10.9 % v 77.4 % + /- 8.9 % , P & lt ; .05 ) . -
pubmed
We conclude that ( 1 )
glutamine and
arginine metabolism is altered with very small
tumors , ( 2 ) although the flux of
Arg to
Gln was increased in TB and
rats , the small increase in
Arg to
Gln can not explain the observed large increase in
Gln production . -
pubmed
We have assessed its effects on normal and malignant cells in preclinical animal models of localized and disseminated
human hematopoietic neoplasms . -
pubmed
Flavopiridol had a marked apoptotic effect documented by DNA nick - end labeling , or DNA agarose gels in xenografts of
human hematopoietic tumors HL-60 ,
SUDHL-4 , and
Nalm / 6 . -
pubmed
This activity was manifested in our study as a potent antileukemia or antilymphoma effect in
human tumor xenografts , which was dose and schedule dependent . -
pubmed
These findings provide compelling evidence for the use of
flavopiridol in
human hematologic malignancies . -
pubmed
We show the complications observed in a large series of
children with
hypomelanosis of Ito (
HI ) or
incontinentia pigmenti achromians , studied in a neurology service over 30 years . -
pubmed
Thirty - seven
patients ( 49 % ) had
seizures , consisting of
infantile spasms in six cases ( 8 % ) . -
pubmed
For this reason , we investigated for the presence and specificity of platelet and thyroid autoantibodies in 18
TAD patients with
thrombocytopenia , 19
TAD patients without
thrombocytopenia and in 22
patients with primary
AITP without clinical signs of
TAD . -
pubmed
Thyroid autoantibodies were found in 89 % of
patients with
TAD and
thrombocytopenia , in 95 % of
patients with
TAD without
thrombocytopenia , and in 18 % of
patients with primary
AITP . -
pubmed
Vibrio vulnificus is an opportunistic
human pathogen causing
wound infections and
septicemia , characterized by
hemorrhagic and edematous damage to the skin . -
pubmed
BACKGROUND : Vascular access
thrombosis accounts for at least $ 1 billion dollars in annual expenses and 25 % of hospitalizations for chronic hemodialysis
patients . -
pubmed
METHODS : Ninety - five accesses in 91
CHD patients were prospectively followed over 18 months . -
pubmed
STUDY DESIGN : We retrospectively reviewed the protocol sheets of 503 consecutive
patients with
gastroesophageal reflux disease who underwent laparoscopic fundoplication over a period of 5 years . -
pubmed
All
pneumothoraces occurred in the first 100
patients . -
pubmed
Five
patients had significant operative
bleeding ; two of them required laparotomy for
bleeding control . -
pubmed
Gastric ulcer was diagnosed in six
patients . -
pubmed
One alcoholic
patient died of acute
pancreatitis . -
pubmed
Although
human rights issues are often linked with
AIDS issues abroad , in the US they receive insufficient attention in our response to women 's HIV risk . -
pubmed
Diptericin 's submicromolar potency against
Escherichia coli strains indicated that , in a manner similar to drosocin , the presence of the
carbohydrate side chain is not necessary to kill
bacteria . -
pubmed
Neither the N - terminal , drosocin - analog fragment , nor the C - terminal ,
glycine - rich attacin - analog region was active against any of the
bacterial strains studied , regardless of whether the
Gal - GalNAc disaccharide units were attached . -
pubmed
Mycobacterium leprae particle agglutination in diagnosis and monitoring of treatment of
leprosy . -
pubmed
leprae particle agglutination ( MLPA ) in 156 untreated
leprosy patients . -
pubmed
Seropositivities in control serum specimens were 11.3 per cent in active
pulmonary tuberculosis patients , 2.6 per cent in dermatologic patients and 4.4 per cent in a healthy population , in low titers . -
pubmed
Additionally , it provides an alternative tool in monitoring
leprosy patients under MDT . -
pubmed
The local control and biological
relapse - free survival rates appear to be improved by high dose conformal radiotherapy from 20 to 30 % for
patients with intermediate and high risk of
relapse . -
pubmed
The
palladium may be stimulated in
Parkinson ' s patients with major iatrogenic
involuntary movements . -
pubmed
A total of 60.9 % of the
patients failed nonoperative management within 24 hours of admission ; 8 % failed 9 days or later after
injury . -
pubmed
Laparotomy was ultimately performed in 19.9 % of
patients with small
hemoperitoneum , 49.4 % of patients with moderate
hemoperitoneum , and 72.6 % of patients with large
hemoperitoneum . -
pubmed
Analysis of
infection of blood monocyte - derived macrophages by primary
HIV strains shows that approximately one - third of 32 isolates was consistently high - replicating , one - third was consistently low - replicating , and one - third was dependent on the donor of the macrophages ( i.e. -
pubmed
The location of this bottleneck in the
HIV replication cycle differs according to viral
strain and host - cell donor , but it was exerted before the stage of reverse transcription in 80 - 90 % of cases . -
pubmed
For this , a susceptible
bladder tumor line
TCCSUP was treated with the inhibitory dose ( 50 microM ) of
genistein for various periods of time , followed by mRNA isolations , cDNA probe preparations , and hybridization individually to cDNA chips containing 884 sequence - verified known
human genes . -
pubmed
METHODS : Five
puppies had
JPS performed with electrocauterization at 12 , 16 , 20 , 22 , and 24 weeks of age , respectively . -
pubmed
The final mean AA in
dogs that had
JPS was 25 degrees greater than preoperative values ; 40 % increased over control . -
pubmed
The final mean DI in
dogs having
JPS was 0.28 , 47 % improved over preoperative values and 58 % better than control . -
pubmed
Mean pelvic dimensions in
dogs that had
JPS were 18 % less than control . -
pubmed
CLINICAL SIGNIFICANCE :
Dysplastic hips in young
dogs were significantly improved by JPS . -
pubmed
A non - significant reduction in incidence was observed for
cryptococcosis by 45 % ( 0.81 vs. 0.45;P= 0.11 ) ,
oesophageal candidiasis by 29 % ( 3.34 vs. 2.39;P= 0.053 ) and
mycobacterium avium complex by 18 % ( 1.58 vs. 1.29;P= 0.4 ) , and a non - significant increase was observed for
tuberculosis by 17 % ( 0.62 vs. 0.73;P= 0.66 ) and
non - Hodgkins lymphoma (
NHL ) by 51 % ( 0.43 vs. 0.65;P= 0.31 ) . -
pubmed
In the acute study ,
obese rats received either vehicle ( water ) or
irbesartan 1 hour before the experiment . -
pubmed
RESULTS : In the presence of
xanthurenic acid human lens epithelial cells undergo apoptosis - like cell
death . -
pubmed
BACKGROUND AND PURPOSE : Epidemiological studies have shown an increased risk of
venous thrombosis in
women taking third - generation
oral contraceptives , ie , those containing the
progestogens desogestrel or
gestodene . -
pubmed
Women with a first
ischemic stroke were compared with control
women without
vascular diseases . -
pubmed
All
patients and control subjects filled in a questionnaire about the use of
oral contraceptives and risk factors for
ischemic stroke . -
pubmed
RESULTS : Two hundred three
women with an
ischemic stroke and 925 control women were included . -
pubmed
Functional
visual loss in
patients with
bilateral ocular coloboma . -
pubmed
The aim of this study was to investigate the pathological changes of the lateral pterygoid muscle ( LPM ) using magnetic resonance imaging ( MRI ) in
patients with anterior disk displacement with nonreduction ( ADDnr ) of the temporomandibular joint (
TMJ ) and to compare the abnormal findings of the LPM with the clinical symptoms and other pathological MRI alterations of the TMJ . -
pubmed
The results of this study indicate that the pathological changes of the LPM in
TMJs with
ADDnr could be detected by MRI and have a significant association with the main clinical symptoms of the
patients . -
pubmed
Our patient was a
woman , old 78 years old who admitted for treatment of
hypertrophic cardiomyopathy . -
pubmed
At the same time , she had a
urinary infection , caused by
Escherichia coli , which confirmed possible relationship between primary
biliary cirrhosis and occurrence of some Gramm negative bacteria , reported elsewhere . -
pubmed
PATIENTS : Thirty - seven
patients with
schizophrenia . -
pubmed
This induction may result in formation of
neurotoxic metabolites , leading to increased AIMS scores and a higher frequency of
tardive dyskinesia compared with
patients without these alleles . -
pubmed
We performed a
tryptophan depletion ( TD ) test in 17
FM patients and 17 controls . -
pubmed
Additionally
pain perception was monitored in the
FM patients . -
pubmed
FM patients and controls exhibited a decrease of
TRP and
KYN during TD . -
pubmed
5 - HIAA levels also decreased in all controls and in 11
FM patients , but showed a marked increase in 6
FM patients . -
pubmed
Pain perception was not affected in the FM
patients . -
pubmed
These data demonstrate an altered
TRP metabolism in a subgroup of
FM patients , where the TD seems to activate
5 - HT metabolism . -
pubmed
Intraarterial thrombolysis for
perioperative stroke in
patients undergoing cardiac operations . -
pubmed
METHODOLOGY : In the past 4 years , 205
patients with
non - small cell lung carcinoma (
NSCLC ) underwent surgical resection at Chiba Cancer Center , Chiba , Japan . -
pubmed
Mucin production and composition is altered in dextran sulfate
sodium - induced
colitis in
rats . -
pubmed
BACKGROUND : The role of neoadjuvant chemotherapy for
patients with multiple ( five or more ) bilobar hepatic
metastases irrespective of initial resectability is still under scrutiny . -
pubmed
METHODS : Retrospective data were collected from 71
patients after hepatectomy for five or more bilobar
liver tumours . -
pubmed
CONCLUSION : In
patients with bilateral multiple
colorectal liver metastases , neoadjuvant chemotherapy before hepatectomy was associated with improved survival and enabled complete resection with fewer extended hepatectomies . -
pubmed
Despite the
trauma of dissection and special metabolic requirements , the physiological properties of funiculi of the
mammalian spinal cord can be studied in vitro . -
pubmed
In the present study , we genotyped 121 Japanese
patients with
Parkinson ' s disease (
PD ) and 100 controls . -
pubmed
Our results may help understand the mechanism that cause complications of
levodopa therapy in
PD patients . -
pubmed
We report here a case of immune - mediated
haemolytic anaemia associated to
imatinib mesylate successfully treated with
prednisone in a
patient with
CML . -
pubmed
This case demonstrated that
patients treated with
imatinib mesylate can present immune - mediated
haemolysis and adequate management of this event can be done maintaining the drug and associating
corticosteroids . -
pubmed
Retransplantation in
patients with graft loss caused by
polyoma virus nephropathy . -
pubmed
The characteristics and outcome in 10
patients who underwent retransplantation after losing their renal grafts to BK virus - associated
nephropathy (
BKAN ) are described . -
pubmed
From this collective experience from five transplant centers ( although the follow - up after retransplantation was not extensive ) , it can be concluded that
patients with graft loss caused by
BKAN can safely undergo retransplantation . -
pubmed
To clarify some of the circumstances in which this immune response can vary , we examine the immune - response profile of
sheep protected against the clinical disease by prior vaccination with
strain Rev. -
pubmed
EXEGESIS : We reported a 45 year - old
woman with distal lower limb
lymphedema . -
pubmed
Levodopa intake increases plasma levels of
S - adenosylmethionine in treated
patients with
Parkinson disease . -
pubmed
SAM caused
Parkinson disease (
PD)-like symptoms in
rodents . -
pubmed
The objective of the study was to demonstrate an effect of acute
levodopa intake on
SAM synthesis in the plasma of treated
PD patients . -
pubmed
This is often observed in untreated
PD patients who receive
levodopa for the first time , or in more advanced , fluctuating
PD patients , when they turn from the OFF to the ON phase . -
pubmed
Because
SAM in higher dosages may also counteract the antiparkinsonian efficacy of
levodopa according to
animal trials , this
SAM increase may hypothetically contribute to the onset of wearing - off phenomena and other clinical signs of limited efficacy of
levodopa during long - term treatment with
levodopa in
PD patients . -
pubmed
Central nervous system - related permanent consequences in
patients with
Langerhans cell histiocytosis . -
pubmed
PROCEDURE : In this single center study , 25
LCH patients observed for a median time of 10 years 3 months underwent a uniform thorough follow - up program including neuropsychological testing and electrophysiological evaluation . -
pubmed
Intracranial abnormalities were the most frequent including
diabetes insipidus (
DI ) in seven
patients ,
anterior pituitary deficiencies in five
patients , and
neurodegenerative CNS disease in five
patients . -
pubmed
Brain stem evoked potentials showed abnormalities in four of nine tested
patients , all of these four had
neurodegeneration on MRI . -
pubmed
Developing the sterile insect technique for
Cryptophlebia leucotreta ( Lepidoptera : Tortricidae ): influence of radiation dose and release ratio on
fruit damage and population growth in field cages . -
pubmed
The effect of radiation dose and different release ratios of treated ( T ) to untreated ( U )
Cryptophlebia leucotreta ( Meyrick ) ( Lepidoptera : Tortricidae ) , on the incidence of
fruit damage , the competitiveness of the treated males , and population growth was examined inside field cages . -
pubmed
This study investigated the gender difference of HDLC levels in elderly Japanese
patients with
CAD . -
pubmed
PATIENTS : A total of 163 elderly ( & gt ; or = 65 years )
outpatients with
CAD ( 128
men aged 70.6+/-5.2 years and 35
women aged 74.1+/-6.0 years [ mean+/-SD ] ) were investigated . -
pubmed
The AD 2
strain isolated from feces of a healthy
dog in Slovakia was characterized phenotypically by the conventional tests and commercial identification kits API Staph and ID32 Staph . -
pubmed
Results of biochemical tests identified the
strain as
S. - pubmed
In the
goat , maternal hypophysectomy on Day 60 of gestation or treatment with 5 mg
bromocriptine / day between Days 60 and 120 of gestation did not affect
fetal body weights or the weights of the fetal adrenals , thyroid , pituitary gland or gonads when examined at 120 days gestation . -
pubmed
In three
rodent models of PAH , a 1 hour / day exposure to
CO reverses established
PAH and
right ventricular hypertrophy , restoring right ventricular and pulmonary arterial pressures , as well as the pulmonary vascular architecture , to near normal . -
pubmed
Value of
fructosamine measurement in pregnant
women with
abnormal glucose tolerance . -
pubmed
The aim of this study was to determine whether the level of serum
fructosamine can be diagnostic for
abnormal glucose tolerance in pregnant
women . -
pubmed
CONCLUSIONS :
Fructosamine can be used to monitor the
glucose level of pregnant
women with
abnormal glucose tolerance , and to identify the
patients at high risk of
abnormal glucose tolerance , but can not be used to predict
gestational diabetes mellitus (
GDM ) in early stage of pregnancy . -
pubmed
OBJECTIVE : To research the treatment effect of complex prescription of Chinese crude drug in
BALB / c athymic mice with
human liver cancer , which were built by
Bel-7402 . -
pubmed
RESULT : All of the 48 athymic
mice survived 12 to 28 days ( Ms 24 days ) and every
mouse with
liver cancer demonstrated by dissection . -
pubmed
Cardiotoxicity of Ma Huang /
caffeine or
ephedrine /
caffeine in a
rodent model system . -
pubmed
When this
syndrome of clinical signs emerged ,
animals were moribund sacrificed , and a histological analysis for
heart lesions performed . -
pubmed
Newer antidepressants should be considered as first - line agents for the treatment of
depression in
patients with and without
cardiovascular disease . -
pubmed
Periodic pharyngolaryngoscopy is recommended for curatively treated
ESCC or
BC patients . -
pubmed
In 60
women undergoing vaginal hysterectomy , a total of 420
pain evaluations of postoperative
pain intensity were performed by an observer and the
patients . -
pubmed
The
patients themselves evaluated their
pain on a visual analogue scale and on a 101 - point numerical rating scale . -
pubmed
There was good agreement between
pain intensity on the visual analogue scale and the 101 - point numerical rating scale in the
patients ' self - assessment ( r ( 2)=0.74;y=0.81x+11.4 ) . -
pubmed
The
pain intensities determined by the observer on the visual analogue scale were markedly lower , on average than the
patients ' self - report ( P<0.0001 ) . -
pubmed
The
pain intensities rated by the observer on the visual analogue scale were on averange 37.7 % of the
patients ' self - assessments on the visual analogue scale . -
pubmed
The purpose of this study was to determine differences in outcomes of
patients with
mucinous colorectal
adenocarcinoma according to the type of mucin expressed . -
pubmed
RESULTS : Of the 418
patients treated in this period , only 35 had a
mucinous adenocarcinoma . -
pubmed
Is screening for urinary
porphobilinogen useful among
patients with acute
polyneuropathy or
encephalopathy ? -
pubmed
Porphyrin metabolites were screened in 108
patients with acute
polyneuropathy or
encephalopathy associated with
pain and/or
dysautonomia , who attended neurological wards , in order to evaluate the number of
patients with acute
porphyria . -
pubmed
Surprisingly many
patients ( 11 % ) had previously undiagnosed acute
porphyria . -
pubmed
Half of these
patients had had mild to moderate symptoms of acute
porphyria previously . -
pubmed
Of the 108
patients studied , the levels of urinary
porphyrins or their precursors were normal in the majority ( 79 % ) of the cases , who commonly had
Guillain - Barre syndrome ( 40 % ) . -
pubmed
Epileptic seizures were also frequent ( 18 % ) , but none of the
patients with acute
porphyria had solely
epileptic seizures without prolonged
confusion ( & gt;or= 1 day).Based on our findings , acute inherited
porphyria is not infrequent among the selected group of neurological
patients and screening of urinary PBG is cost - beneficial . -
pubmed
Since the correct diagnosis of a
hereditary disease is essential , genetic screening should be performed whenever possible for
patients with clinically and biochemically confirmed
acute porphyria . -
pubmed
PET / CT and head - and - neck MRI are suggested for the initial staging of
NPC patients . -
pubmed
Central sleep apnea in
patients with
congestive heart failure . -
pubmed
CLINICAL RELEVANCE : Straight anteriorization of the tibial tuberosity may be a useful adjunct for
patients with
medial articular defects of the patellar or trochlea in whom anteromedialization would be otherwise contraindicated . -
pubmed
[ Opioids and cognition in
patients with
chronic pain : a systematic review ] . -
pubmed
OBJECTIVE : The increasing use of opioids by
patients suffering from
chronic pain caused by different etiologies , and the possible effects of those substances on everyday activities , require careful evaluation of their effects . -
pubmed
For this purpose , a systematic review was developed to assess the influence of opioids on the cognitive function in
patients with
chronic pain . -
pubmed
The inclusion criteria were : clinical trials or case reports which included
patients with
chronic pain in treatment with opioids , cognitive assessment by specific tests and publication in English , Spanish or Portuguese . -
pubmed
All better quality controlled trials did not show
cognitive impairment of
patients under opioid therapy . -
pubmed
CONCLUSION : These results must be confirmed by additional randomized trials including a greater number of
patients with
chronic pain . -
pubmed
Mycobacterium celatum pulmonary infection mimicking
pulmonary tuberculosis in a patient with
ankylosing spondylitis . -
pubmed
Mycobacterium celatum , a slow - growing acid - fast bacillus , is an uncommon cause of
human infection , mainly occurring in patients with
AIDS . -
pubmed
The literature was reviewed and clinical features of eight
HIV - negative patients with
M. - pubmed
Borna disease virus (
BDV ) is a neurotropic RNA virus that establishes non - cytolytic persistent
infection in the central nervous system of warm - blooded animals . -
pubmed
Depending on the host species and the route of
infection ,
BDV persistence can modulate neuronal plasticity and animal behaviour and/or may provoke a T cell - mediated immunopathological reaction with high mortality . -
pubmed
Therefore ,
BDV functions as a model pathogen to study persistent
virus infection in the central nervous system . -
pubmed
Progressive multifocal leukoencephalopathy in a
patient with
Good ' s syndrome . -
pubmed
Herein we report the case of a 79 - year - old
woman with
GS who developed subacute motor deficits and cognitive changes . -
pubmed
Polyoma virus JC , the agent of
progressive multifocal encephalopathy (
PML ) , was identified in cerebrospinal fluid samples and brain biopsy specimens . -
pubmed
OBJECTIVE : To explore an exercise method for the prevention and treatment of the
patients with
shoulder and back fasciitis . -
pubmed
All the
patients were followed up for 6 to 26 months , the
recurrence were observed . -
pubmed
RESULTS : After 3 weeks treatment , the scores of
pain , sense of heaviness , strip sign ,
tenderness , shoulder and back function of the
patients in two groups had significant differences compared with those before treatment ( all P & lt ; 0.01 ) . -
pubmed
After treatment , the scores of
pain , sense of heaviness , strip sign ,
tenderness , shoulder and back function of the
patients in the treatment group were lower than those in the control group ( P & lt ; 0.05 ) . -
pubmed
The development of
oral squamous cell cancer (
OSCC ) is a multistep process involving the accumulation of multiple genetic alterations modulated by genetic pre - disposition and environmental influences such as
tobacco and
alcohol use ,
chronic inflammation , and
viral infections . -
pubmed
BACKGROUND : Uninterrupted use of ocular
hypotensive medication by
glaucoma patients is important to prevent
vision loss , but medication persistence is poor . -
pubmed
Transient
cardiac ischaemia and abnormal variations in systemic blood pressure in unselected primary
open angle glaucoma patients . -
pubmed
PURPOSE : To investigate the relationship between the occurrence of transient
cardiac ischaemic episodes and variations in the ambulatory 24 - h blood pressure and heart rate measurements in a group of unselected
glaucoma patients . -
pubmed
PARTICIPANTS : Twenty - four consecutive
glaucoma patients and 23 age - matched controls were included in the present study . -
pubmed
RESULTS : Overall , in
glaucoma patients , LIE was also associated with a significant increase in diastolic and mean BP ( p = 0.007 and p = 0.003 respectively ) and HR ( p = 0.007 ) . -
pubmed
However , six
glaucoma patients ( 46.86 % ) failed to demonstrate any significant BP changes during the LIE ( p & gt ; 0.05 ) . -
pubmed
CONCLUSIONS : As opposed to age - matched controls , in
glaucoma patients the systemic circulatory responses associated with significant transient
cardiac ischaemic events were highly variable . -
pubmed
In North America , the indigenous groups have been identified as a population with increased risk of
pneumococcal colonization and
pneumococcal invasive disease . -
pubmed
A total of 65
strains were isolated ; 11 % of the mothers and 69 % of the children carried
S. - pubmed
[ Recurrent
thromboses and
hemorrhagic complications in
patients with
antiphospholipid syndrome during therapy with
warfarin plus
aspirin ] . -
pubmed
SUBJECTS AND METHODS : Eighty - two
patients diagnosed as having the
antiphospholipid syndrome were examined . -
pubmed
Hemorrhagic complications of antithrombotic therapy developed in 46.9 and 60.6 % of Groups 1 and 2
patients , respectively ( p = 0.26 ) . -
pubmed
Beneficial effects of
sodium or
ethyl pyruvate after
traumatic brain injury in the
rat . -
pubmed
Body composition assessed by the 4 - component model and association with lung function in 6 - 12 - y - old
children with
cystic fibrosis . -
pubmed
BACKGROUND :
Malnutrition is an indicator of a poor prognosis in
patients with
cystic fibrosis (
CF ) . -
pubmed
OBJECTIVE : We measured BC by using the 4CM in 6 - 12 - y - old
children with
CF to 1 ) compare findings with those of healthy , matched control children and reference data ; 2 ) relate BC to lung spirometry [ forced expired volume in 1 s ( FEV1 ) ] ; and 3 ) compare findings with those from more commonly used 2CM techniques . -
pubmed
DESIGN : One hundred clinically stable
children with
CF ( 57 %
girls ) aged 6 - 12 y were measured by using the 4CM . -
pubmed
Children with
CF underwent spirometry ( FEV1 ) . -
pubmed
They showed that
ester hydrolysis and oxidation play predominant roles in
mammalian metabolism of
pyrethroids and that rapid metabolism leads to low
mammalian toxicity . -
pubmed
BACKGROUND :
Fruits and
vegetables are an essential part of the
human diet , but many people do not consume the recommended serves to prevent
cardiovascular disease and
cancer . -
pubmed
The biological characterization of
( 99m ) Tc - BnAO - NI as a SPECT probe for imaging
hypoxia in a
sarcoma - bearing
mouse model . -
pubmed
A biodistribution study after intravenous injection of
( 99m ) Tc - BnAO - NI in
KHT sarcoma - implanted
C3H mice was performed . -
pubmed
The distribution of
( 99m ) Tc - BnAO - NI in
KHT sarcoma - bearing
mice revealed rapid clearance from the blood circulation . -
pubmed
Importantly ,
mice inoculated with 4T1LMF4 and 4T1BM2 variants showed a 2.5- to 4 - fold increase in the incidence of spontaneous
metastasis to bone compared to
4T1 tumor - bearing
mice . -
pubmed
This is the first report showing an absence of
NSD in a
human disease , revealing that this surveillance mechanism has exceptions in vivo . -
pubmed
METHODS AND RESULTS : A catheter was implanted into the jugular vein of C57BL/6
mice to allow repeated administration of
eritoran ( 5 mg / kg
body weight ) or placebo . -
pubmed
First , a group of articles was recently published on chemically instead of genetically induced
MKD mouse and cell models , investigating the effects of several
isoprenoid pathway intermediates . -
pubmed
Metallofullerene - based nanoplatform for
brain tumor brachytherapy and longitudinal imaging in a
murine orthotopic xenograft model . -
pubmed
Human glioblastoma U87MG cells were implanted by using stereotactic procedures into the brains of 37 female
athymic nude - Foxn1nu mice and allowed to develop into a
tumor for 8 days . -
pubmed
Survival studies involved 20
mice that received infusion of a nanoplatform by means of convection - enhanced delivery ( CED ) 8 days after
tumor implantation . -
pubmed
PARTICIPANTS :
Patients with
acute stroke given intravenous thrombolytic therapy between 6 September 2007 and 1 October 2010 . -
pubmed
After review in person , the
stroke specialist tended to treat
patients with a higher median modified Rankin Scale ( 1 vs 0 by telephone ) . -
pubmed
MATERIAL AND METHOD : Between 1.1.2004 and 31.12.2005 we treated 71
patients with 102
idiopathic clubfeet with the Ponseti method . -
pubmed
endemicum ) ,
Treponema paraluiscuniculi , and the unclassified Fribourg - Blanc treponeme cause clinically distinct diseases , these pathogens are genetically and antigenically highly related and are able to cause persistent
infection . -
pubmed
endemicum isolate ( Iraq B ) , the unclassified Fribourg - Blanc isolate , and the Cuniculi A
strain of
T. - pubmed
We investigated the influence of the lateral prefrontal cortex ( PFC ) in a response inhibition task by using cognitive electrophysiology in
prefrontal lesion patients . -
pubmed
Therapeutic strategies for
patients with
micropenis or
penile dysmorphic disorder . -
pubmed
Corrective surgery for
micropenis can be performed in
patients with realistic expectations . -
pubmed
BACKGROUND : Intra - articular
corticosteroid injections are a safe and effective treatment for
patients with
juvenile idiopathic arthritis . -
pubmed
OBJECTIVE : The purpose of this study was to report the spectrum of care , technique and safety of ultrasound - guided
corticosteroid injection therapy in
patients with
juvenile idiopathic arthritis and to propose an age - weight - joint - based
corticosteroid dose protocol . -
pubmed
MATERIALS AND METHODS : A retrospective analysis was performed of 198
patients ( ages 21 months to 28 years ) referred for treatment of
juvenile idiopathic arthritis with
corticosteroid therapy . -
pubmed
An age - weight - joint - based
corticosteroid dose protocol is effective and integral to interdisciplinary care of
patients with
juvenile idiopathic arthritis . -
pubmed
442
asthmatic children and 191 controls were genotyped by RFLP . -
pubmed
We performed a multicentric , prospective , and nonrandomized trial from July 2008 to July 2009 , wherein 2 groups of
patients with
prolapse and
hemorrhoids were treated with a single PPH or a D - PPH . -
pubmed
The primary outcome was evaluation of safety and efficacy of the
D - PPH procedure in selected
patients with large
hemorrhoidal prolapse . -
pubmed
RESULTS : In all , 281 consecutive
patients suffering from
hemorrhoidal prolapse underwent surgery , of whom 74 were assigned intraoperatively to D - PPH , whereas 207 underwent single PPH . -
pubmed
CONCLUSIONS : Our data support the hypothesis that an accurate intraoperative
patient selection for single ( PPH ) or double ( D - PPH ) stapled technique will lower in a significant way the incidence of
recurrence after Longo 's procedure for
hemorrhoidal prolapse . -
pubmed
In this double - blinded , placebo - controlled , randomized trial , a total of 74 healthy middle - aged
overweight women ( 25 & lt;=
BMI & lt;= 30 kg / m(2 ) ) received either 250 mg
magnesium in the form of
magnesium oxide or placebo daily for 8 weeks . -
pubmed
We have recently reported a long - lasting decrease in circulating gammadelta T cells in
osteoporotic patients on oral
amino - bisphosphonates (
N - BPs ) . -
pubmed
Subjects with mild ( Child - Pugh A , Group A , n=8 ) and moderate ( Child - Pugh B , Group B , n=9 )
liver impairment and
subjects with normal liver function ( Group DA and DB , both n=9 ) received a dose of 100 mg
almorexant . -
pubmed
No reliable
animal model is available for studying
keloids . -
pubmed
PARTICIPANTS :
Keloid fibroblasts were received from the Baylor College of Medicine , and additional
keloid fibroblasts were enzymatically isolated from the dermal layer of lesions removed from consenting
patients at The Johns Hopkins Hospital . -
pubmed
( 2 ) As there are differences between pharmacokinetic processes in the normal and pathological states , how to express characteristic "
syndromes " in an
animal model ? -
pubmed
Candida glabrata cells suspended in water are under hypo - osmotic stress and undergo cell
death in 1 - 2 days , unless they are at a density of more than 10(5 ) CFU mL(-1 ) . -
pubmed
[ Effects of XELOX regimen as neoadjuvant chemotherapy on radical resection rate and prognosis in
patients with advanced
gastric cancer ] . -
pubmed
OBJECTIVE : The purpose of this study was to investigate the efficacy and mechanism of
oxaliplatin in combination with
capecitabine (
XELOX ) regimen as neoadjuvant chemotherapy in the treatment of
patients with advanced
gastric cancer . -
pubmed
METHODS : Eighty - five
patients with advanced
gastric cancer ( stage IIB and IIIC ) were randomly divided into two groups : neoadjuvant chemotherapy group ( 40 cases ) and surgery alone group ( 45 cases ) . -
pubmed
In the surgery alone group ,
patients directly received radical resection of
gastric cancer . -
pubmed
CONCLUSIONS : XELOX regimen as neoadjuvant chemotherapy in the treatment of
patients with advanced
gastric cancer can effectively improve the R0 resection rate and prolong the survival time of the
patients . -
pubmed
Evaluation of
aldosterone concentrations in
dogs with
hypoadrenocorticism . -
pubmed
BACKGROUND : Some
dogs with
primary hypoadrenocorticism (
HA ) have normal
sodium and
potassium concentrations , a phenomenon called atypical
Addison ' s disease . -
pubmed
The assumption that the
zona glomerulosa and
aldosterone secretion in these
dogs are normal seems widely accepted ; however ,
aldosterone measurements are missing in most published cases . -
pubmed
ANIMALS : Seventy
dogs with
HA , 22
dogs with diseases mimicking
HA , and 19 healthy
dogs . -
pubmed
Aldosterone was low or undetectable in 67/70
dogs with
HA independently of
sodium and
potassium levels . -
pubmed
CONCLUSION AND CLINICAL IMPORTANCE :
Cortisol and
aldosterone secretion is compromised in
dogs with
HA with and without
electrolyte abnormalities . -
pubmed
The term atypical
Addison ' s disease , used for
dogs with primary
HA and normal
electrolytes , must be reconsidered ; other mechanisms allowing normal
electrolyte balance without
aldosterone should be evaluated in these
dogs . -
pubmed
Black disease is an
acute disease of
sheep and
cattle . -
pubmed
In this work , artificial spiking of down - scaled models for the manufacturing process of an inactivated pandemic
influenza virus vaccine were used to investigate inactivation of
PCV1 and the physico - chemically related
porcine parvovirus (
PPV ) by
formalin and ultraviolet - C ( UV - C ) treatment as well as removal by the purification step
sucrose gradient ultracentrifugation . -
pubmed
Still , the inactivated pandemic
influenza vaccine manufacturing process provides for robust virus reduction , in addition to the already implemented testing for
PCV1 to avoid any contaminations . -
pubmed
OBJECTIVE : To determine the effect of
placental abruption on the outcome of
infants born between 22 and 26 weeks of gestation . -
pubmed
Effects of yoga training in
patients with
chronic obstructive pulmonary disease : a systematic review and meta - analysis . -
pubmed
CONCLUSIONS : The current limited evidence suggested that yoga training has a positive effect on improving lung function and exercise capacity and could be used as an adjunct pulmonary rehabilitation program in
COPD patients . -
pubmed
METHODS : Prospective observational cohort of adult
patients admitted to a Level I
Trauma Center within 6 h of
injury . -
pubmed
Group 1
patients had the lowest incidence of
coagulopathy and
disseminated intravascular coagulopathy , and in general presented with better coagulation profile measured by either classic coagulation tests , thromboelastography or clotting factors . -
pubmed
Isolated severe
TBI was not an independent risk factor for the development of
coagulopathy ( OR 1.06 ; 0.35 - 3.22 CI , p = 0.92 ) , however , isolated severe
TBI patients who developed
coagulopathy had higher mortality rates than isolated severe
TBI patients without
coagulopathy ( 66 vs. 16.6 % , p & lt ; 0.05 ) . -
pubmed
However , severe
TBI patients who develop
coagulopathy have extremely high mortality rates . -
pubmed
Remote magnetic navigation for persistent
atrial fibrillation ablation via a retrograde aortic access : an approach for
patients after
atrial septal defect device closure . -
pubmed
Patterns of conservation in the evolution of the glycogen / starch branching and debranching enzymes hint at some as yet unknown mechanisms , as mutations disrupting these patterns lead to a variety of
genetic diseases in
humans and other
mammals . -
pubmed
Grass pollen sublingual immunotherapy : a double - blind , placebo - controlled study in elderly
patients with
seasonal allergic rhinitis . -
pubmed
BACKGROUND : This study evaluates the safety and efficacy of specific sublingual immunotherapy ( SLIT ) against grass pollen allergens in
patients & gt;60 years of age with
seasonal allergic rhinitis (
SAR ) and/or
asthma . -
pubmed
CONCLUSIONS : SLIT in elderly
patients with a
grass pollen allergy generated a significant clinical improvement in the active group compared with the placebo group for grass pollen season . -
pubmed
Detection of
RHDV strains in the
Iberian hare (
Lepus granatensis ): earliest evidence of rabbit
lagovirus cross - species infection . -
pubmed
Although a related virus severely affects hares , cross - species
infection was only recently described for new variant
RHDV in
Cape hares (
Lepus capensis mediterraneus ) . -
pubmed
We sequenced two
strains from dead
Iberian hares (
Lepus granatensis ) collected in the 1990s in Portugal . -
pubmed
This is the earliest evidence of
RHDV affecting a species other than
European rabbits . -
pubmed
We have thus excluded peripheral contributions by using an
animal model of early
conductive hearing loss (
CHL ) that provides auditory deprivation but does not induce
cochlear damage . -
pubmed
Beneficial effect of an
omega-6 PUFA - rich diet in non - steroidal anti - inflammatory drug - induced
mucosal damage in the
murine small intestine . -
pubmed
The
mucosal damage induced by
indomethacin was significantly lower in
mice fed the
safflower oil diet than in
mice fed the beef tallow or
fish oil diet ( P & lt ; 0.05 ) . -
pubmed
MATERIALS AND METHODS : A total of 64 anaesthetized
patients with
paralysis were enrolled in a single - blind , randomized control trial to be intubated with one of the devices . -
pubmed
CONCLUSION : In
individuals with non - specific
LBP and
reduced hip rotation , clinical intervention of providing exercises targeted at the hip can be beneficial in improving
pain and function , with strengthening exercises most beneficial for improving function . -
pubmed
The last few years have seen a dramatic improvement in the management of this
tumor as nearly 50 - 70 % of selected
patients with early
HCC survive for a median period of up to 5 years after liver transplantation , resection or local ablation . -
pubmed
Short tandem repeats ( STRs ) are implicated in dozens of
human genetic diseases and contribute significantly to genome variation and instability . -
pubmed
The selected studies involved a total of 871
stroke subjects . -
pubmed
A 36 - year old
man presented with a 1 - year history of progressive
unsteadiness . -
pubmed
Hybrid
wound dressings with controlled release of antibiotics : Structure - release profile effects and in vivo study in a
guinea pig burn model . -
pubmed
The latter was tested on a
guinea pig burn model , compared to the neutral non - adherent dressing material
Melolin ( Smith & amp ; Nephew ) and
Aquacel Ag ( ConvaTec ) . -
pubmed
We retrospectively reviewed data , including preoperative ultrasonography and/or computed tomography results , on
patients who underwent total thyroidectomy for
thyroid cancer at our hospital between 2006 and 2012 . -
pubmed
Sixty - eight
patients had
papillary thyroid cancer , and 30 had
follicular cancer . -
pubmed
Identification of lymph node involvement during preoperative radiologic investigations was strongly prognostic for
recurrence : 35.3 % of
patients with positive preoperative ultrasonography findings and 62.5 % of those with positive preoperative computed tomography findings had
recurrence ( p = 0.01 ) . -
pubmed
Wound - healing potential of the fruit extract of
Phaleria macrocarpa . -
pubmed
Experimentally , two - centimeter - wide full - thickness - deep skin excision
wounds were created on the posterior neck area of the
rats . -
pubmed
The
wounds were topically treated with gum acacia as a vehicle in the control group , intrasite gel in the reference group , and 100 and 200 mg / mL
P. - pubmed
Norovirus GII ( AF 5 2 % , 95 % CI 3 0 - 7 1 ) , rotavirus ( 4 8 % , 4 5 - 5 0 ) , Campylobacter spp ( 3 5 % , 0 4 - 6 3 ) , astrovirus ( 2 7 % , 2 2 - 3 1 ) , and Cryptosporidium spp ( 2 0 % , 1 3 - 2 6 ) exhibited the highest attributable burdens of
diarrhoea in the first year of life . -
pubmed
AIMS : The high
HIV /
AIDS burden in Sub - Saharan Africa has led to
cryptococcosis becoming a public health concern . -
pubmed
RESULTS : The intraspecific variation between tested
strains allowed for their delineation into three traditional varieties of
C. - pubmed
A 62 - year - old
woman presented to our hospital with a 1 - week history of progressive
dyspnea and difficulty in walking . -
pubmed
CT imaging findings in
patients with advanced
hepatocellular carcinoma treated with
sorafenib : Alternative response criteria ( Choi , European Association for the Study of the Liver , and modified Response Evaluation Criteria in Solid Tumor ( mRECIST ) ) versus RECIST 1.1 . -
pubmed
MATERIALS AND METHODS : This retrospective study included 60
patients with advanced
HCC treated with
sorafenib . -
pubmed
CONCLUSION : This study found a significant difference between Choi versus RECIST 1.1 , mRECIST and EASL when evaluating the response to
sorafenib in
HCC patients . -
pubmed
In 735
patients with a current episode of
major depression and 456 never - depressed control participants
pain thresholds ( pressure
pain thresholds , PPTs ) were measured at the index finger pad and self - rated suprathreshold
pain intensity ratings were obtained using the
Pain Sensitivity Questionnaire ( PSQ)-minor subscore , an instrument that assesses
pain intensity in daily life situations . -
pubmed
BACKGROUND : Older
adults have the highest rates of hospitalization and mortality from
traumatic brain injury (
TBI ) , yet outcomes in this population are not well studied . -
pubmed
OBJECTIVE :
Children with
Down syndrome (
DS ) have a high incidence of
middle ear disorders and
congenital abnormalities of the external , middle and inner ear . -
pubmed
The aim of the present study was to compare the WAI measurements of
children with
DS with those of typically developing , normal - hearing
children according to their tympanometric findings . -
pubmed
METHODS : Four groups of
children with
Down syndrome ( age range : 2 years and 4 months to 16 years and 3 months ; mean age : 8.5 yr ) with normal tympanograms ( 19 ears ) , flat tympanograms ( 13 ears ) , mild negative pressure tympanograms ( 6 ears between -100 and -199 daPa at the admittance peak ) and severe negative pressure tympanograms ( 4 ears at -200 daPa or lower at the admittance peak ) were assessed . -
pubmed
METHODS : We performed an observational cohort study on adult
trauma patients ( & gt;=18 years ) , who required admission to the intensive care unit and who survived hospitalization between 1997 and 2011 . -
pubmed
METHOD : The efficacy of sequential treatment for nineteen
vertical semicircular canal S - BPPV patients(Group A ) and forty - five vertical semicircular canal O -
BPPV patients(Group B ) who were admitted to our hospital between January 2014 and July 2015 was retrospectively analyzed and compared , treatment of five cases with horizontal semicircular canal S - BPPV was reported here as well . -
pubmed
Hypolipidemic effects of HVC1 in a high
cholesterol diet - induced
rat model of
hyperlipidemia . -
pubmed
HVC1 , a novel formation containing four herbs , was developed and its hypolipidemic effects in
rats with high
cholesterol diet ( HCD)-induced
hyperlipidemia were investigated . -
pubmed
In particular , moderate CR in
humans ameliorates multiple metabolic and hormonal factors that are implicated in the pathogenesis of
type 2 diabetes ,
cardiovascular diseases , and
cancer , the leading causes of morbidity , disability and mortality . -
pubmed
Over a period of 8 consecutive years , a retrospective chart review was performed of 105
patients who underwent robotic - assisted surgery for benign
esophageal diseases by a single surgeon . -
pubmed
Abnormal regional spontaneous neuronal activity associated with symptom severity in treatment - naive
patients with
obsessive - compulsive disorder revealed by resting - state functional MRI . -
pubmed
In this current study , we aimed to investigate cerebral regions with abnormal spontaneous activity using resting - state functional magnetic resonance imaging ( fMRI ) and further explored the relationship between the spontaneous neuronal activity and symptom severity of
patients with
OCD . -
pubmed
Thirty - one
patients with
OCD and 32 age - and sex - matched normal controls received the fMRI scans and fractional amplitude of low - frequency fluctuation ( fALFF ) approach was applied to identify the abnormal brain activity . -
pubmed
We found that
patients with
OCD showed decreased fALFF not only in the cortical - striato - thalamo - cortical ( CSTC ) circuits like the thalamus , but also in other cerebral systems like the cerebellum , the parietal cortex and the temporal cortex . -
pubmed
Effect of
Androgen on Normal Biodistribution of
[ 18F ]- 2 '- Fluoro-5 - methyl-1 - beta - D - arabinofuranosyluracil (
18F - FMAU ) in Athymic Non -
tumor - bearing Male
Mice . -
pubmed
MATERIALS AND METHODS : Non - castrated ( n=4 ) and castrated ( n=4 ) athymic non -
tumor - bearing male
mice served as models for presence and absence , respectively , of
androgen . -
pubmed
The
hepatitis E virus (
HEV ) is a major cause of acute
hepatitis globally . -
pubmed
In addition , these isolated compounds were assessed for antimicrobial activity including antimalarial ( against
Plasmodium falciparum , K-1
strain ) , antifungal ( against
Candida albicans ) , antibacterial ( against
Bacillus cereus ) activities . -
pubmed
BACKGROUND : Nab -
paclitaxel plus
gemcitabine has become a standard treatment regimen in
patients with metastatic
pancreatic adenocarcinoma ; however , retrospective data suggest that
gemcitabine might be inefficient in 50 - 60 % of
patients and thus not an optimum regimen in combination with nab -
paclitaxel . -
pubmed
Eligible
participants were previously untreated
patients with metastatic
pancreatic adenocarcinoma ( previous adjuvant chemotherapy after curative intent resection was allowed if the interval between the end of chemotherapy and
relapse was more than 12 months ) . -
pubmed
Patients continued treatment until unacceptable
toxicity ,
disease progression , or
patient withdrawal . -
pubmed
At 4 months , 40 ( 56 % , 90 % CI 45 - 66 ) of 72
patients in the
leucovorin and
fluorouracil group were alive and free from
disease progression ( 21 [ 54 % , 40 - 68 ] of 39
patients in the
gemcitabine group were also alive and progression - free at 4 months ) . -
pubmed
Forty
patients with high - grade
gliomas and 44 with
metastases were enrolled in this study . -
pubmed
Thirty - five
patients with high - grade
glioma and 30
patients with
metastases had FLAIR images . -
pubmed
After the publication of results from the National Institute of Health - sponsored Trial to Assess Chelation Therapy ( TACT ) , a randomized controlled trial ( RCT ) in
patients after
myocardial infarction (
MI ) , there is a renewed interest in clarifying the role of this treatment modality for
patients with
coronary artery disease . -
pubmed
Atopy as a risk factor for
subclinical hypothyroidism development in
children . -
pubmed
METHODS : We enrolled 620
allergic children ( 1.11 - 12.8 years ) consecutively attending to our department . -
pubmed
Results : Forty
patients ( 15
women and 25
men ; median age , 44 years [ range , 22 - 72 years ] ) were enrolled , including 29
patients ( 73 % ) with
GBS ( 90 % Brighton level 1 certainty ) , 7 ( 18 % ) with
encephalitis , 3 ( 8 % ) with
transverse myelitis , and 1 ( 3 % ) with newly diagnosed
chronic inflammatory demyelinating polyneuropathy . -
pubmed
Of these , 35
patients ( 88 % ) had molecular and/or serologic evidence of recent
ZIKV infection in the serum and/or cerebrospinal fluid . -
pubmed
Of the
patients positive for
ZIKV infection , 27 had
GBS ( 18 demyelinating , 8 axonal , and 1
Miller Fisher syndrome ) , 5 had
encephalitis ( 3 with concomitant acute
neuromuscular disease ) , 2 had
transverse myelitis , and 1 had
chronic inflammatory demyelinating polyneuropathy . -
pubmed
Admission to the intensive care unit was required for 9
patients positive for
ZIKV infection ( 26 % ) , and 5 ( 14 % ) required mechanical ventilation . -
pubmed
At 3 months , 2
patients positive for
ZIKV infection ( 6 % ) died ( 1 with
GBS and 1 with
encephalitis ) , 18 ( 51 % ) had
chronic pain , and the median modified Rankin score among survivors was 2 ( range , 0 - 5 ) . -
pubmed
Adherence and feasibility of 2 treatment schedules of
S-1 as adjuvant chemotherapy for
patients with completely resected advanced
lung cancer : a multicenter randomized controlled trial . -
pubmed
BACKGROUND : We conducted a multicenter randomized study of adjuvant S-1 administration schedules for surgically treated pathological stage IB - IIIA
non - small cell lung cancer patients . -
pubmed
METHODS : This is a retrospective case - control cohort study , comprised of
PCOS women ( N=29 ) and normal menstruating
women as controls ( N=20 ) . -
pubmed
RESULTS :
PCOS women showed reduced plasma NOx(
nitrate+
nitrite ) and
H2O2 compared to controls . -
pubmed
H2O2 concentration in
PCOS women was also found to be reduced . -
pubmed
Head and neck cancer patients treated with irradiation often present irreversible salivary gland hypofunction for which no conventional treatment exists . -
pubmed
MiR-186 inhibits cell proliferation and invasion in
human cutaneous
malignant melanoma . -
pubmed
The purpose of this study was to investigate the expression level and functional role of miR-186 in
human cutaneous
malignant melanoma cells . -
pubmed
Conclusions : Our findings suggested that miR-186 exhibit an inhibitory effect on
CMM cell proliferation , migration , and invasion ; thus , may serve as a potential therapeutic target for
human CMM intervention . -
pubmed
Physical Disabilities Related to the Depressive Mental States of Japanese
Patients with Subacute
Myelo - optico - neuropathy . -
pubmed
Objective The aim of this study was to clarify the clinical conditions related to the depressive mental states in Japanese
patients with subacute
myelo - optico - neuropathy (
SMON ) , caused by
clioquinol intoxication more than 40 years previously . -
pubmed
Repeating mental supportive interviews and medical examinations by experts helped to improve the
depressive mental state and revealed close relationship between the mental state and the physical disabilities of the
SMON patients . -
pubmed
All of the
subjects received amblyopic treatment and were divided into 2 groups after 6 months of follow - up : the recovered
amblyopic group with a best - corrected visual acuity ( BCVA ) & gt;=0.8 and the persistent amblyopic group with a BCVA & lt;0.8 on the Landolt C chart . -
pubmed
Results : Forty - four amblyopic
children were included , of which 26 were in the recovered
amblyopic group after 6 months of follow - up . -
pubmed
The
patients with
strabismic anisometropic amblyopia and severe
amblyopia ( initial VA & lt;= 0.3 ) were significantly predisposed to developing persistent
amblyopia ( P=0.049 and P & lt ; 0.001 , respectively ) . -
pubmed
We identified a strong correlation between the presence of
dilated ovarian veins and chronic
pelvic pain in premenopausal parous
patients with
hematuria . -
pubmed
INTRODUCTION : Most
patients ( & gt;70 % ) experience acute
neuropathic symptoms shortly after
oxaliplatin infusions . -
pubmed
Overall , 30%-50 % of
patients suffer from chronic
oxaliplatin - induced
peripheral neuropathy (
OIPN ) . -
pubmed
In
animals , there is a beneficial effect on sensorimotor and
pain disorders , as well as related comorbidities , after repeated administration of
oxaliplatin . -
pubmed
Patients with
colorectal cancer and initiating adjuvant
oxaliplatin - based chemotherapy are eligible . -
pubmed
A 31 - year - old
man with mild
hemophilia B developed a
herniated disc treated with
prednisolone for
back pain . -
pubmed
The respective antibacterial activity of the oils was tested against four bacterial
strains : two Gram - positive
strains ,
Staphylococcus aureus (
ATCC 25923 ) and
Bacillus licheniformis (
ATCC12759 ) , and two Gram - negative
strains ,
Escherichia coli (
ATCC25922 ) and
Klebsiella pneumoniae ( ATCC 13883 ) . -
pubmed
[ Commercially
Communicable Diseases and patients with
hepatitis C virus ] . -
pubmed
This allows us to speed up simulations for in vivo trials , where we obtained peak - to - valley dose ratios of 1.20 + - 0.05 and 6.1 + - 0.2 for proton minibeam irradiations targeting the
tumour and crossing the
rat head . -
pubmed
METHODS : We prospectively calculated FRAX score for hip and major
osteoporotic fractures in
inflammatory bowel disease patients consecutively recruited . -
pubmed
RESULTS : The mean risk of
hip fractures at 10 years , for the 80 recruited
patients , resulted 1.4 % , while the mean risk of major
osteoporotic fractures was 7.8 % . -
pubmed
In a small subset of 8 individuals , a higher relative abundance of
Akkermansia muciniphila was correlated with
type 2 diabetes remission . -
pubmed
These findings could be of particular relevance for future functional studies assessing the effects of
cannabinoids in
horses to manage
pain . -
pubmed
We present a
patient with a
spinocerebellar ataxia (
SCA)-like phenotype who was found to carry an M233V mutation . -
pubmed
A 26 - year - old
man of an Azerbaijani origin presented with a progressive
impairment of coordination followed by
memory impairment . -
pubmed
Given reported promising results of open - label fecal microbiota transplantation ( FMT ) therapy in
patients with predominant
abdominal bloating , we studied efficacy of this treatment in a randomized , placebo - controlled trial . -
pubmed
METHODS :
Patients with refractory
IBS , defined as failure of > = 3 conventional therapies , were randomly assigned to single - dose nasojejunal administration of donor stools ( n=43 ) or autologous stools ( n=19 ) in a double - blind study , performed from December 2015 through October 2017 , and followed for 1 year . -
pubmed
CONCLUSIONS : In a randomized trial of
patients with treatment - refractory
IBS with predominant
bloating , FMT relieved symptoms compared with placebo ( autologous transplant ) , although effects decreased over 1 year . -
pubmed
METHODS : Fifteen
patients with
intracranial arterial stenosis were prospectively enrolled 6 - 8 months after stenting . -
pubmed
RESULTS : During the follow - up period , the WeChat platform was used to refer 8
children with
respiratory infection symptoms to local hospitals for treatment . -
pubmed
Although there are effective treatments available for many , probably most ,
patients with
OCD , a significant number do not respond , or fail to experience a sustained beneficial response . -
pubmed
For
patients with such chronic , disabling and ' treatment - refractory '
OCD , neurosurgical treatments may be considered . -
pubmed
CASE : Seven years after hip arthroscopy for
cam impingement , a 47 - year - old female
patient suffered a valgus impacted
femoral neck fracture of her left hip that was stabilized with cannulated screws . -
pubmed
Primary
hepatic tumors developed in 13 young
women who had been ingesting contraceptive
steroids . -
pubmed
Benign
tumors were successfully resected in eight
women . -
pubmed
One
woman died during hepatic resection for
malignant hepatoma ; in two other cases of
hepatocellular carcinoma ,
tumors were nonresectable . -
pubmed
In two
patients , the
tumor was left in situ after
neoplasm had been excluded by biopsy . -
pubmed
A
patient with severe
alcoholic liver disease , in whom there was almost complete suppression of function of the reticuloendothelial system of the liver as noted on a
99mTc - SC scan is discussed . -
pubmed
A study of total
sleep deprivation for one night was performed on 12
patients with
endogenic depression and 10 with
neurotic depression , as well as a control group of 10 normals . -
pubmed
Fracture of the frontal sinus in
children . -
pubmed
Two juvenile
patients , ages 5 and 8 , had traumatic
fractures of the frontal
sinus that included involvement of the nasal - frontal ducts and posterior tables . -
pubmed
22
patients suffering from acute
myocardial infarction were subjected to daily blood sampling for up to 6 days after admission to hospital . -
pubmed
5
patients with
myocardial ischaemia and
chest pain , but no evidence of
infarction , were similarly investigated as controls . -
pubmed
Infarction patients were divided into three clinical groups : uncomplicated cases , complicated and fatalities . -
pubmed
Four cases ( 3
children and one adolescent ) are presented in which
Parinaud ' s syndrome developed in the course of progressive non - tumorous
hydrocephalus . -
pubmed
Retinal arterioles in the New Zealand
strain of genetically
hypertensive rats . -
pubmed
Reduction of the ( expanded ) body fluid volumes found in some
patients with
renal hypertension may be essential in the management of these cases . -
pubmed
The combined effect of salt depletion ( which increases PRA ) and beta - adrenergic blockade with
propranolol ( during which treatment PRA is lowered ) was systematically studied in 3 groups of
hypertensive patients ( including one group with
chronic renal insufficiency ) . -
pubmed
Once frank
rupture has occurred , the outlook is grave , but immediate surgery and intensive general care can allow survival in up to 50 % of
patients . -
pubmed
Alterations in electroencephalogram activity were not observed in
urethane anaesthetized
animals , whereas 50 % of Hypnorm anaesthetized
animals exhibited
epileptic activity . -
pubmed
induced
epileptic activity in a majority of
animals anaesthetized using
urethane . -
pubmed
Fifty - six
patients ( 60 testes ) who were previously treated with chemotherapy for metastatic
germ cell neoplasm ( originally diagnosed by removal of the contralateral testis or by biopsy of metastatic disease ) underwent sonography followed by orchiectomy . -
pubmed
These results suggest the potential for predicting the pathologic diagnosis in some
patients after receiving chemotherapy for
germ cell neoplasm . -
pubmed
Immunohistochemical study of glial reaction and serum - protein extravasation in relation to
neuronal damage in
rat hippocampus after
ischemia . -
pubmed
Transient
forebrain ischemia of 30 min duration was produced in anaesthetized
rats by four - vessel occlusion . -
pubmed
Between 1962 and 1983 , fourteen
patients ( twenty knees ) had centralization of the fibula for
congenital longitudinal deficiency : tibial , complete . -
pubmed
Attempts to reconstruct the knee joint by centralization of the fibula are not warranted for
patients who have
congenital longitudinal deficiency : tibial , complete . -
pubmed
The models in
rats included " learned helplessness , "
shock - suppressed licking ( Vogel conflict test ) and forced swimming - induced immobility ( " behavioral despair " ) . -
pubmed
The models in
mice included
shock - suppressed exploration ( four plates test ) , spontaneous exploration ( staircase test ) and food consumption in a novel situation ( emotional
hypophagia ) . -
pubmed
Further tests in
rats examined the effects of EGB 761 on memory ( passive avoidance test ) and responsiveness to shock to determine whether the preventive effects observed with
EGB 761 in the learned helplessness procedure were due either to drug - induced
impairment of memory or to reduced
shock sensitivity . -
pubmed
EGB 761 did not affect performance in the passive avoidance task or alter the
animals ' response to electric
shock , suggesting that the effects observed in the learned helplessness procedure were not due to impaired memory or reduced
shock sensitivity . -
pubmed
Anxiolytic - like activity was also seen in the emotional
hypophagia test in
mice where repeated administration of EGB 761 increased the amount of food consumed. -
pubmed
DESIGN : Prospective notification of
patients reaching a defined level of advanced
chronic renal failure ( serum
creatinine concentration greater than or equal to 500 mumol / l or blood
urea concentration greater than or equal to 25 mmol / l ) within one year and follow up for at least three , and , at most , four years after notification . -
pubmed
Fourteen
patients with symptoms of
vertebrobasilar insufficiency caused by
vertebral artery stenosis in the distal first portion underwent surgical reconstruction . -
pubmed
[ Behavior of blood pressure in 3 shift work of
workers with level I WHO
hypertension ] . -
pubmed
Blood pressure tests were carried out on 40 shift
workers with a
hypertension level of 1 ( according to WHO ) . -
pubmed
A
patient with acquired
intestinal malabsorption developed a motor - sensory
polyneuropathy with a recurrent remittent course , normal CSF and reduced motor and sensory conduction velocities . -
pubmed
A similar effect was noted in cells from
patients with
benign hyperplasia (
BPH ) . -
pubmed
A controlled , parallel group study of the analgesic efficacy of
flupirtine maleate , was compared against
diclofenac sodium in 40 orthopaedic
patients with
post - operative pain . -
pubmed
We compared red cell exchange transfusions ( RC Ex ) on the Aminco Celltrifuge ( continuous flow cell separator ) with conventional transfusions in 17
patients aged between 7 and 24 years who have transfusion dependent homozygous
beta - thalassaemia and two other patients with chronic transfusion dependent
anaemias aged 20 and 22 . -
pubmed
[ Pharmacokinetics of
benzylpenicillin and
gentamycin administered by different routes to
patients with acute and chronic nonspecific
lung diseases ] . -
pubmed
Pharmacokinetic studies showed that endobronchial administration of
benzylpenicillin and
gentamicin to
patients with acute and chronic
pneumonia unlike intramuscular administration provided the antibiotic concentrations in bronchial secretions effective against middle sensitive and moderately resistant
strains of microorganisms within 1 - 5 hours . -
pubmed
In this study , we report the use of extracorporeal membrane oxygenation ( ECMO ) to stabilize two
patients with necrotizing
tracheobronchitis . -
pubmed
ECMO and bronchoscopy are effective forms of therapy for
patients with life - threatening necrotizing
tracheobronchitis when conventional modalities of treatment have failed . -
pubmed
The authors describe the course of a severe
asthma emergency in a
boy aged 13 years . -
pubmed
Analyzing data from two large controlled clinical trials in
patients with
chronic liver disease : 1 ) the multicenter trial of
prednisone versus placebo in
cirrhosis conducted by the Copenhagen Study group for
Liver diseases ( CSL-1 ) and 2 ) the multinational trial of
azathioprine versus placebo in
primary biliary cirrhosis (
PBC-1 ) we have developed indices for prediction of prognosis and therapeutic effect using Cox 's multiple regression model for censored survival data . -
pubmed
Several inanimate surfaces ( eg , plastic , wood , and steel ) and particulate fomites ( eg , wood shavings ,
hay , straw , and feces ) , common to the environment of confined small ruminants , were inoculated with
Corynebacterium pseudotuberculosis in axenic purulent exudate that had been surgically removed from a naturally occurring case of caprine caseous
lymphadenitis . -
pubmed
A histochemical study of
amines in palatal tissue from normal and
glycosuric mice . -
pubmed
Auto - immune
myocarditis in
rabbits immunized with
rabbit heart . -
pubmed
Synthesis of
phospholipid in the blood of
patients with
essential hypertension . -
pubmed
[ Immune reactions of
rats with experimental induced
hyperphenylalaninemia ] . -
pubmed
Dietary fats and
atherosclerosis in
rat and
rabbit . -
pubmed
Eosinophilic myositis in
cattle . -
pubmed
[ Changes in the immunobiologic properties of
Ehrlich ascites carcinoma under the effect of suspension from normal
rat tissues . -
pubmed
B lymphocyte studies , in vivo and in vitro , were performed in 28
patients with
systemic lupus erythematosus (
SLE ) . -
pubmed
Pemphigus - like antibodies in the
horse and direct immunofluorescence testing in equine
dermatophilosis . -
pubmed
Indirect immunofluorescence testing for
pemphigus - like antibodies was performed on 79
horses : 28
horses with various nonpemphigus
dermatologic diseases , 21
horses with various
nondermatologic diseases , and 30 normal
horses . -
pubmed
Pemphigus - like antibodies were detected in 6
horses : 3 normal
horses with titers of 1:40 , 2
horses with
dermatophilosis at titers of 1:10 and 1:80 , and 1
horse with
lymphosarcoma at a titer of 1:320 . -
pubmed
It was concluded that
equine pemphigus - like antibodies are a potential source of misinterpretation and misdiagnosis in indirect immunofluorescence testing . -
pubmed
It was concluded that
equine dermatophilosis is a potential source of misinterpretation and misdiagnosis in direct immunofluorescence testing . -
pubmed
Chick embryo fibroblast ( CEF)-grown stocks of the WSN
strain of
influenza A(
HINI ) contain two variants which were designated F and C for fuzzy and clear plaque morphology on
Madin - Darby bovine kidney ( MDBK ) cells . -
pubmed
Amelioration of mesangial volume and surface alterations following islet transplantation in
diabetic rats . -
pubmed
This information is especially helpful in azotemic
patients with
hypertension . -
pubmed
Culex ( Melanoconion ) taeniopus is a vector of
Venezuelan encephalitis ( VE ) virus at a marsh focus in Guatemala and has low mesenteronal thresholds for
infection by and transmission of two enzootic
strains of
VE virus . -
pubmed
taeniopus to
mesenteronal infection by this VE
strain probably represents a key factor in the apparent disappearance of epizootic
VE virus from the marsh focus following the 1969 outbreak . -
pubmed
[
Ischemic cerebrovascular disease in
patients with
atrial fibrillation ] . -
pubmed
The purpose of this retrospective study was to elucidate 1 ) which subgroups are prone to have
ischemic cerebrovascular disease (
CVD ) among
patients with
atrial fibrillation (
Af ) , 2 ) vulnerable period of
CVD after the diagnosis of chronic
Af and 3 ) the clinical efficacy of antiplatelet therapy in chronic nonvalvular Af
patients . -
pubmed
During 9 years , a total of 479
patients included 124 cases with
paroxysmal Af , 30 cases with paroxysmal
Af initially which later changed to chronic
Af and 325 cases with chronic
Af were enrolled . -
pubmed
This case provides support for the general concept of multidirectional differentiation in
human epithelial cancers and in particular for the association of poor
tumor differentiation with neuroendocrine expression in
prostatic carcinoma . -
pubmed
Effect of multiple denervations on the exercise
hyperpnea in awake
ponies . -
pubmed
Third , in
ponies with all three denervations together , the predominant response was an increase , not a decrease , in the exercise
hyperventilation ; this increase was greater than that predicted from the individual lesions . -
pubmed
Fission
yeast minichromosome loss mutants mis cause lethal
aneuploidy and replication abnormality . -
pubmed
Oscillations in cytoplasmic free
calcium concentration in
human pancreatic islets from subjects with normal and
impaired glucose tolerance . -
pubmed
Such oscillations were observed even in some islets from
patients with
impaired glucose tolerance . -
pubmed
In one islet from a
diabetic patient there was no response to
glucose , whereas that islet displayed [
Ca2+]i - oscillations in response to
tolbutamide , suggesting that
sulphonylurea treatment can mimic the complex pattern of
glucose - induced [
Ca2 +]i - oscillations . -
pubmed
Interestingly , even subjects with
impaired glucose tolerance had islets that responded with oscillations in [
Ca2 +]i upon
glucose stimulation , although it is not known to what extent the response of these islets was representative of most islets in these
patients . -
pubmed
UNLABELLED : Radiofrequency current catheter ablation was attempted for 17 morphologies of
ventricular tachycardia (
VT ) in 14
patients . -
pubmed
Five
patients had underlying
heart disease . -
pubmed
After ablation , 14
VTs ( 14/17 = 82 % ) of 11
patients ( 11/14 = 79 % ) could not be induced by electrical stimulation . -
pubmed
In 4
patients , application of radiofrequency current was required 10 or more times because of a possible large arrhythmogenic area , or because of reinduction of
VT , even though
VT was terminated by radiofrequency current . -
pubmed
No major complication was observed except for complete
right bundle branch block in 1
patient . -
pubmed
[ Polysomnographical studies of a
patient with severe
myoclonic epilepsy in infancy ] . -
pubmed
In order to evaluate the brain function of a
boy with severe
myoclonic epilepsy , we performed serial polysomnographical studies . -
pubmed
PBMC for
patients with
autoimmune diseases produce autoantibodies of the same specificities but at lower levels compared to the donor . -
pubmed
SCID recipients of
patients ' PBMC fail to develop clinical disease although some histological lesions suggestive of
autoimmunity have been reported . -
pubmed
Transfer of autoimmunity from
rodents to
SCID mice has been successful in some instances . -
pubmed
Despite obstacles related to limited survival and varying degrees of
graft vs host disease (
GVHD ) , SCID
mice should prove to be a useful vehicle to explore autoantibody regulation . -
pubmed
As a result , prognostic factors have been evaluated in an attempt to identify those
patients with presumed early stage
disease who will be at high risk for
recurrence . -
pubmed
RESULTS : When
ER and PR and combined ER / PR status were analyzed separately ,
patients with
receptor - positive lesions had significantly better
disease - free survival than those with
receptor - negative lesions . -
pubmed
A 12 - year - old
boy with a history of "
migraine "
headache presented with an increasingly severe
headache accompanied by
emesis and
unsteadiness . -
pubmed
Although rare in
children , isolated
angiitis of the central nervous system can occur in
children and aggressive immunosuppression should be considered as the mode of therapy . -
pubmed
Recruitment of T lymphocytes to lymph nodes in
patients with
HIV infection is critical to the pathogenesis of disease . -
pubmed
25
rats with
alimentary hypercholesterolemia induced by diet rich in
cholesterol and
mercazoline were exposed to frontomastoid impulse current ( 1000 Hz , 0.75 mA ) . -
pubmed
A retrospective analysis of the MRI studies of 25
patients with pathologically proven
pineal region tumours was performed , focused on the relationship between the
tumour and neighbouring structures . -
pubmed
In 10 of the 14
patients ( 71 % ) with
germ cell tumours tectal compression was of the invasive type ; 8
patients ( 57 % ) had multiple
tumours and in 13 ( 93 % ) the
tumor margins were irregular . -
pubmed
One - kidney , one clip ( 1K,1C ) and two kidney , one clip ( 2K,1C ) Goldblatt
hypertensive rats were treated for 2 wk with
bosentan ( 100 mg.kg-1.day-1 ) in their
chow , and
systolic blood pressure was measured by the tail - cuff method . -
pubmed
Treatment with
bosentan did not result in a significant change in
systolic blood pressure or in the structure of small coronary , renal cortical , mesenteric , or femoral arteries in 1 K , 1C or in 2 K , 1C
hypertensive rats . -
pubmed
alpha - Conotoxin imperialis I inhibits
nicotine - evoked hormone release and cell proliferation in
human neuroendocrine carcinoma cells . -
pubmed
[ Interrelations of the
calcium concentration in breast milk with maternal intake of
cow 's milk and milk products ,
bone resorption and bone mineral density during lactation ] . -
pubmed
coli in large quantities and should prove useful as a standardized allergen for sensitive and specific immunodiagnosis of
ABPA , especially in
patients with central
bronchiectasis . -
pubmed
These sperm antigens are involved in binding to
zona pellucida of the
human oocyte . -
pubmed
The recombinant
human sperm NZ-2 antigen may find applications in the development of a contraceptive vaccine , and diagnosis and treatment of
infertility in
humans . -
pubmed
A randomized multicenter trial is currently underway and is evaluating the long - term visual results documented in 609
patients with subfoveal
CNV who underwent control and eventual PDT at 3 - month intervals . -
pubmed
If PDT proves to be beneficial , an easy and non - invasive treatment modality could be offered to numerous
patients who demonstrated occult classic
CNV and are otherwise facing an extremely poor prognosis . -
pubmed
ST tendons were harvested either with or without their distally attached tibial bone plugs from
human cadavers and were folded to a three - stranded graft . -
pubmed
In our experiments , cultured hepatocytes isolated from normal and
hypothyroid adult
rats were used . -
pubmed
Therefore , the effect of
tri - iodothyronine ( T3 ) was investigated using cultured hepatocytes from
hypothyroid rats as an in vitro model . -
pubmed
Cold -
shock domain proteins in
vertebrates contain a highly conserved domain which is related to the
Escherichia coli cold -
shock proteins . -
pubmed
Here we report the cloning of a cold -
shock domain protein from
zebrafish embryo . -
pubmed
Using the combination of PCR techniques with degenerate primers , 5'RACE and 3'RACE , the full length cDNA of a cold -
shock domain protein in the
zebrafish embryo was successfully cloned without constructing and screening a library . -
pubmed
HIV recent advances in
AIDS research : genetics , molecular biology and immunology . -
pubmed
BACKGROUND :
Tobacco smoking is the single most preventable cause of
death in the United States
today . -
pubmed
STUDY DESIGN : Twenty - four
women diagnosed as having
gestational diabetes were compared to 22 nondiabetic , matched controls . -
pubmed
Women with
gestational diabetes had a significantly lower level than those with normal
glucose tolerance . -
pubmed
We undertook a randomized , crossover study to investigate the effects of 6 wk of treatment with regular
terbutaline ( 1 mg four times a day ) , regular
budesonide ( 400 microg twice a day ) , combined treatment , and placebo in
subjects with mild to moderate
asthma . -
pubmed
Chloptosin ( 1 ) was found to induce apoptotic activity in apoptosis - resistant
human pancreatic adenocarcinoma cell line
AsPC-1 and showed a strong antimicrobial activity against Gram - positive bacteria including
methicillin - resistant
Staphylococcus aureus . -
pubmed
The misdiagnosis of surgically treatable conditions in as many as 21 ( 13.5 % ) of the 156
patients calls for better neurological evaluation of
patients admitted for
stroke in tertiary and non - tertiary hospitals . -
pubmed
New monitoring techniques as the measurement of
systolic pressure variations or transoesophageal Doppler echocardiography will probably find a place in the management of
trauma patients in the near future . -
pubmed
CASE : A 29 - year - old
woman presented with a serious
vulvar hematoma caused by a straddle bicycle accident . -
pubmed
The following variants were found in
scrapie - affected
goats :
VV(21 ) , LL(23 ) , GG(49 , )
SS(49 ) , HH(143 ) , HR(143 ) , RR(154 ) , PP(168 ) , PP(240 ) , SP(240 ) and
SS(240 ) . -
pubmed
Allergic and photoallergic contact dermatitis to
Olaquindox in a
pig breeder with prolonged
photosensitivity . -
pubmed
This case report details the evaluation and treatment of a rapidly progressive and destructive
subtalar lesion that occurred in a healthy 27 - year - old
man after incidental
trauma . -
pubmed
This retrospective MRI analysis of a group of
patients with
polymicrogyria , without associated
porencephaly or
schizencephaly , was conducted to elucidate gross morphological findings of
polymicrogyria in a clinical population . -
pubmed
Seventy - one
patients with
polymicrogyria diagnosed by MRI were reviewed by two radiologists . -
pubmed
The
polymicrogyria was unilateral in 30 ( 42 % )
patients , bilateral in 41 ( 58 % )
patients . -
pubmed
We describe a unique case , whereby a
patient presenting with
seizures and slight impairment of higher functions , underwent frontal lobectomy for a mass lesion . -
pubmed
The
patient remained well after 18 months of follow - up with no radiological progression of a known
tumor residuum . -
pubmed
Authors tested the efficacy of an in - home respite intervention to reduce peripheral markers of SAM activation and psychological distress in spousal caregivers of
patients with
Alzheimer disease . -
pubmed
Activity of
ascaridol from the anthelmintic herb
Chenopodium anthelminticum L. against sensitive and multidrug - resistant
tumor cells . -
pubmed
Ascaridol is the active principle of the
American wormseed Chenopodium anthelminticum L. We isolated
ascaridol from a commercial preparation of Chenopodium oil and analyzed its activity against different
tumor cell lines in vitro (
CCRF - CEM ,
HL60 ,
MDA - MB-231 ) . -
pubmed
Rhizomelic chondrodysplasia punctata is a
human autosomal recessive disorder characterized by
skeletal , eye and brain abnormalities . -
pubmed
The
rats were randomized to four groups : intravenous
valsartan ( 10 mg / kg , n = 8) ,
irbesartan ( 10 mg / kg , n = 8) , or saline vehicle ( controls , n = 14 ) over 30 minutes before reperfused
myocardial infarction , and sham ( n = 8) . -
pubmed
After washing and reacting with
4 - chloro-1 - naphthol and
H2O2 , the appearance of purple
spots indicated the presence of
B. - pubmed
Blood pressure and renal clearances in
hypertensive dogs following
tissue injury . -
pubmed
The following study improves the effectiveness of pelvic floor exercise in
women with
stress urinary incontinence . -
pubmed
A group of 27
women with
stress urinary incontinence performed specific pelvic floor exercises twice a week for 45 minutes under a therapist 's supervision for a period of 12 weeks . -
pubmed
The urodynamic results showed that 48.2 % of the patients did not have
urinary loss , however , 51,8 % of the
patients that had a loss showed an increase in vesicle volume , and only 7.3 % remained unchanged . -
pubmed
MATERIAL AND METHODS : One hundred and seven
subjects with ( cases ) and 52
subjects without ( controls )
chronic arsenic poisoning were examined by spirometry . -
pubmed
Multi - institutional randomized phase II trial of the
epothilone B analog
ixabepilone (
BMS-247550 ) with or without
estramustine phosphate in
patients with progressive castrate metastatic
prostate cancer . -
pubmed
PURPOSE : To evaluate the antitumor activity and safety of the
epothilone B analog ,
ixabepilone , with or without
estramustine phosphate (
EMP ) , in chemotherapy - naive
patients with progressive castrate metastatic
prostate cancer . -
pubmed
Grades 3 and 4 toxicities experienced by more than 5 % of
patients included
neutropenia ( 22 % ) ,
fatigue ( 9 % ) , and
neuropathy ( 13 % ) on the
ixabepilone arm , and
neutropenia ( 29 % ) ,
febrile neutropenia ( 9 % ) ,
fatigue ( 9 % ) ,
neuropathy ( 7 % ) , and
thrombosis ( 6 % ) on the
ixabepilone +
EMP arm . -
pubmed
CONCLUSION :
Ixabepilone , with or without
estramustine phosphate , is well tolerated and has antitumor activity in
patients with castrate metastatic
prostate cancer . -
pubmed
Moreover , these
Allium plants showed chemopreventive effects against
human leukemia cells . -
pubmed
We present a case of a 47 - year - old
patient with
arterial hypertension and progressive ST segment changes with a T wave inversion during 2 years of observation . -
pubmed
During subsequent two last years the
patient was repeatedly hospitalised due to
chest pain . -
pubmed
Important progress in the diagnosis of
Chlamydia trachomatis (
C. - pubmed
CONCLUSION : Supplementary
AVP infusion in
patients with advanced
vasodilatory shock and severe
postoperative multiple organ dysfunction syndrome did not compromise cutaneous reactive
hyperaemia and flowmotion when compared with
norepinephrine infusion alone . -
pubmed
We report about two
patients with
extramedullary plasmocytoma , one of them with an extremely rare triple manifestation in the upper airway . -
pubmed
In
patients with
atherosclerosis , antiplatelet therapy is indicated and treatment of vascular risk factors should have high priority . -
pubmed
METHODS : Ten
patients with
AR undergoing pollen SLIT with a weekly dose of 200,000 SQ - U , 10 with a weekly dose of 24,000 SQ - U of glycerinated mixture of
Betula verrucosa ,
Corylus avellana and
Alnus glutinosa and 10 with placebo were included in the study . -
pubmed
CONCLUSIONS : Sublingual immunotherapy induced a dose - dependent systemic allergen - specific immunological response in
children with
AR . -
pubmed
A 34 - year - old
man was admitted with
dyspnea and low grade
fever . -
pubmed
METHODS : Three separate conformal plans were generated for 37
patients with
lung cancer : plan 1 corrected for heterogeneity , plan 2 did not correct for heterogeneity , and plan 3 used identical beams and monitor units from plan 2 but with heterogeneous calculations . -
pubmed
In the present study , we examined differences in responses to chemotherapy in microvascular EC lines from tumoral ( T - EC ) and
normal ( N - EC )
mouse liver tissues . -
pubmed
CASE : We present the case of a 25 - year - old
woman with appendiceal
carcinoid tumor treated with intraperitoneal
cisplatin for peritoneal
recurrence after a fertility - sparing cytoreductive procedure . -
pubmed
Fluid dynamics of gingiva in
diabetic and systemically healthy
periodontitis patients . -
pubmed
The objectives of this study were ( i ) to investigate the alterations in the fluid dynamics of periodontium in
diabetic periodontitis patients , and present the association of this phenomenon with the metabolic control of
DM ; ( ii ) to reveal any correlation between the fluid dynamics of periodontium and clinical signs of
periodontal disease in
DM and
periodontitis . -
pubmed
DESIGN : Fifteen well - controlled
diabetic chronic periodontitis patients ( Group 1 ) , 14 systemically healthy
chronic periodontitis patients ( Group 2 ) , and 14 systemically and periodontally healthy individuals were included in the study . -
pubmed
Apoptosis is a cause of the limbic system neuronal cells defect in
patients suffering from
depression . -
pubmed
METHOD : The study comprised of 32
patients diagnosed with
depression . -
pubmed
METHODS : We conducted a randomized , double - blind , placebo - controlled , parallel - group study of
BtA ( Dysport ) for
leg spasticity in 64
children with
cerebral palsy . -
pubmed
Young
children are at increased risk for
hypoxaemia and
hypercapnea during flexible laryngoscopy due to the small size and increased collapsibility of their airways . -
pubmed
OBJECTIVE : The objective of this study was to detail the epidemiologic characteristics and natural history of
HIV-1 natural viral suppressors ( NVSs ) , a cohort of
HIV-1 - infected individuals who are able to suppress viral replication to undetectable levels in the absence of therapy . -
pubmed
The incidence and prevalence of
NVS were calculated by performing a chart review on all
patients seen in 1 clinic in a 10 - year period . -
pubmed
INTRODUCTION : To avoid the risk of complications of biliary drainage , a feasibility study was carried out to determine whether it might be possible to fast - track surgical treatment , with resection before biliary drainage , in jaundiced
patients with proximal
pancreatic / peri - ampullary malignancy . -
pubmed
CONCLUSIONS : Fast - track management by resection without biliary drainage of selected
patients with distal
biliary strictures is safe and has the potential to reduce the waiting time to surgery , overall numbers of biliary drainage procedures and the complications thereof . -
pubmed
Several randomized trials of catheter - directed thrombolysis versus operative revascularization in
patients with acute lower extremity
ischemia were performed in the mid-1990 s. Although the outcomes of these trials were not definitive , they did provide insight into potential uses and techniques of catheter - directed thrombolysis and lytic agents . -
pubmed
Tumor tissue specimens from two
patients with
MPM were engrafted subcutaneously in
SCID mice and blood samples were obtained and pooled every 2 weeks after xenotransplantation until 14 weeks when the
mice were killed . -
pubmed
No
patients with
lung cancer regardless of asbestos exposure exhibited positive antibody titer against the two antigens . -
pubmed
RECENT FINDINGS :
Vitamin D deficiency is common among both healthy and ill
adolescents worldwide , even in sunny countries . -
pubmed
SUMMARY : Further studies are needed to examine the implications of
vitamin D deficiency among
adolescents and the most appropriate treatment regimens to prevent this problem . -
pubmed
There are sufficient data to support the importance of educating , preventing , and treating
vitamin D deficiency in
adolescents to improve their long - term health . -
pubmed
The toxicities of these peptides to
microbial and
cancer cells were generally & lt;200 microM. -
pubmed
[ Randomized control study of sequential non - invasive following short - term invasive mechanical ventilation in the treatment of
acute respiratory distress syndrome as a result of existing
pulmonary diseases in elderly
patients ] . -
pubmed
OBJECTIVE : To evaluate the feasibility and the efficacy of sequential non - invasive mechanical ventilation ( MV ) following short - term invasive MV in the treatment of
acute respiratory distress syndrome (
ARDS ) consequent to
pulmonary diseases in the elderly
patients . -
pubmed
METHODS : Thirty - two elderly
patients of
ARDS were enrolled and grouped into two groups ( sequential therapy group and control group ) randomly ( 16 cases in each group ) . -
pubmed
CONCLUDING REMARKS :
Patients on antipsychotic drugs should undergo regular testing of blood
sugar , lipid profile , as well as
body weight , waist circumference and blood pressure , with recommended time intervals between measures . -
pubmed
METHODS : The role of
17beta - estradiol ,
medroxyprogesterone acetate (
MPA ) , and
drospirenone during
renal injury was studied in
Wistar rats subjected to uni - nephrectomy plus
aldosterone salt treatment . -
pubmed
RESULTS :
Aldo - salt treatment of intact , ovariectomized , and
estradiol - treated female
rats resulted in remnant
kidney hypertrophy without structural damage . -
pubmed
Losartan therapy in
adults with
Marfan syndrome : study protocol of the multi - center randomized controlled COMPARE trial . -
pubmed
Aortic disease , leading to progressive
aneurysmal dilatation and dissection is the main cause of morbidity and mortality of
Marfan patients . -
pubmed
beta blockers and elective surgery ) does postpone but can not prevent
aortic complications in these
patients . -
pubmed
The main objective of this trial is to assess whether
losartan treatment leads to a clinically relevant decrease of
aortic dilatation in adult
patients with
Marfan syndrome . -
pubmed
We will enroll 330
patients with
MFS who will be randomly assigned to receive
losartan or not . -
pubmed
DISCUSSION : The COMPARE study will provide important evidence of effects of
losartan treatment in adult
Marfan patient population . -
pubmed
The management of
patients with
aneurysmal subarachnoid hemorrhage (
SAH ) requires a fundamental knowledge of the disease , its therapeutic options and possible complications . -
pubmed
This article provides an overview about the pre- , peri- and postoperative management of
patients with
SAH . -
pubmed
Functional magnetic resonance imaging ( fMRI ) data were recorded in 23 participants with
PTSD ( 13
women , 10
men ) , 21
trauma - exposed controls ( 9
women , 12
men ) , and 42 non -
trauma - exposed controls ( 22 women , 20 men ) while they viewed masked facial expressions of fear . -
pubmed
METHODS : All
patients admitted to Christchurch Public Hospital with
AP between July 2005 and December 2008 were identified from a prospectively collected database . -
pubmed
Patients with
biliary AP had significantly higher median ( range )
ALT than those with non - biliary causes ( 200 units / l [ 63 - 421 units / l ] vs. 33 units / l [ 18 - 84 units / l ] ; P & lt ; 0.001 ) . -
pubmed
Special attention should be paid to
patients with
pseudoexfoliation . -
pubmed
Exploring new applications for
Rhodiola rosea : can we improve the quality of life of patients with short - term
hypothyroidism induced by hormone withdrawal ? -
pubmed
The latter option is simpler but induces a profound state of
hypothyroidism , which results in physical and mental complaints that may interfere severely with the
patient 's activities of daily living . -
pubmed
Rhodiola rosea is a popular plant in traditional medical systems in Eastern Europe and Asia with a reputation for stimulating the nervous system , decreasing
depression , enhancing work performance , and eliminating
fatigue , all features of clinical
hypothyroidism . -
pubmed
rosea as a viable alternative treatment for the symptoms of short - term
hypothyroidism in
patients with
DTC who require hormone withdrawal . -
pubmed
This study aimed to investigate the differential effect and mechanism of
tumor microenvironments , cycling
hypoxia and non - interrupted
hypoxia , on
tumor cell radiosensitivity in the
human U87 glioblastoma tumor model . -
pubmed
We exposed
U87 cells and
mice bearing
U87 glioma to experimentally imposed cycling or non - interrupted hypoxic stress in vitro and in vivo prior to treatment with ionizing irradiation . -
pubmed
Furthermore , we compared the omega-3 index in 14
OHCA -
patients suffering their first
MI with that of 185 first - time
MI -
patients without
SCA ; mean values being 4.59 % and 6.48 % , respectively ( p = 0.002 ) . -
pubmed
METHODS : Between 1/1988 and 2/2001 , 111 consecutive pulmonary resections were conducted in
patients with
bronchial carcinoids . -
pubmed
RESULTS : 97
patients with typical and 14 with atypical
carcinoids were identified . -
pubmed
The preoperative diagnosis of typical or atypical
carcinoid had been correct in 56
patients ( 50.5 % ) . -
pubmed
In
patients with typical and atypical
carcinoids , the 5 - year survival rates were 94 % and 82 % , respectively ( n.s . ) -
pubmed
CONCLUSIONS :
Patients with
bronchial carcinoids who underwent a radical oncological resection with mediastinal lymphadenectomy have very good survival chances . -
pubmed
METHODS : A nonrandomized , retrospective chart review was performed on pediatric
patients ( younger than 18 years of age ) treated with a 360 - degree suture trabeculotomy for
glaucoma . -
pubmed
CONCLUSIONS :
Children with a range of
ocular pathologies can be successfully treated with 360 - degree suture trabeculotomy . -
pubmed
Natural orifice translumenal endoscopic surgery inguinal
hernia repair : a survival
canine model . -
pubmed
RESULTS : All
animals thrived postoperatively and did not manifest signs of
peritonitis or
sepsis at any point . -
pubmed
A 31/2 - year - old apparently healthy
girl with normal development presented with
steatorrhoea . -
pubmed
BACKGROUND :
Patients with
chromosome 5 abnormalities and high - risk
myelodysplastic syndromes or
acute myeloid leukemia have a poor outcome . -
pubmed
We hypothesized that increasing doses of
lenalidomide may benefit this group of
patients by inhibiting the
tumor clone , as assessed by fluorescence in situ hybridization for del(5q31 ) . -
pubmed
Using the International Working Group criteria for
acute myeloid leukemia and
myelodysplastic syndrome the overall response rate in treated
patients with
acute myeloid leukemia was 20 % ( 3/15 ) , while that for patients with
myelodysplastic syndrome was 36 % ( 4/11 ) . -
pubmed
CONCLUSIONS : Our data support a role for higher doses of
lenalidomide in poor prognosis
patients with
myelodysplastic syndrome and
acute myeloid leukemia with deletion 5q . -
pubmed
Although
SP cells isolated from some adult tissues have been reported elsewhere , isolation and characterization of
human trophoblast SP remained to be reported . -
pubmed
Their low toxicity towards
mice fibroblasts at maximal concentrations , their antioxidant activity , comparable or even higher than that of
ascorbic acid as determined by direct quenching of the
DPPH radical , and their potential for significantly altering total and LDL
cholesterol levels , suggest that these conjugates merit further studies in the treatment of
cardiovascular or other related diseases . -
pubmed
Eight
patients were admitted for severe , refractory
gastrointestinal bleeding , seven of whom were actively
bleeding . -
pubmed
Causes of
bleeding were
gastric varices secondary to
portal hypertension ( n = 3 ) ;
gastroduodenal artery aneurysm or fundal
aneurysmal arterial malformation ( n = 3 ) ; and Dieulafoy 's
ulcer ( n = 2 ) ; the latter five
patients having arterial
bleeding . -
pubmed
Metrics of cellular and vascular infiltration of
human acellular dermal matrix in
ventral hernia repairs . -
pubmed
BACKGROUND :
Human acellular dermal matrix is used for ventral
hernia repair , as it resists
infection and remodels by means of surrounding tissue . -
pubmed
METHODS : Fifty - six
guinea pigs underwent inlay
human acellular dermal matrix ventral
hernia repair with the basement membrane oriented toward or away from the peritoneum . -
pubmed
CONCLUSIONS : Cellular and vascular infiltration into
human acellular dermal matrix for
ventral hernia repairs was greater from musculofascia than from subcutaneous fat , and the basement membrane inhibited cellular and vascular infiltration . -
pubmed
Chronic
amitriptyline overdose in a
child . -
pubmed
We describe a case of a 6 - year - old
girl who was prescribed
amitriptyline 30 mg nightly for
sleep problems , but was mistakenly given 300 mg ( 15 mg / kg ) nightly for over a month . -
pubmed
She presented to the local
children 's hospital in
status epilepticus with significant
cardiac conduction abnormalities on ECG . -
pubmed
In this report , we describe a 60 - year - old
woman with
chronic kidney disease whose kidney biopsy showed
FSGS . -
pubmed
METHODS : The antiproliferative effect of
erufosine in vitro was determined by the
MTT dye reduction assay , and the antineoplastic efficacy on
tumor growth was investigated by relating the mean total
tumor volumes of treated and control
rats . -
pubmed
Moreover , administration of
erufosine to
rats bearing autochthonous
methylnitrosourea - induced
rat mammary carcinomas caused a significant dose - related
tumor remission by more than 85 % ( p & lt ; 0.05 ) , which was well tolerated , as evidenced by a body
weight loss of maximally 7 % and reduced
tumor - related mortality ( 2 of 35 instead of 6 of 18 controls , p & lt ; 0.002 ) . -
pubmed
CONCLUSIONS : The results clearly indicate that
erufosine possesses high antineoplastic activity not only in
human breast cancer cell lines in vitro but also in
rat mammary carcinoma in vivo . -
pubmed
To determine if characteristics of the microbiome are associated with these phenotypes we used a phylogenetic microarray to compare small intestine bacterial communities of wild type and congenic
CF mice . -
pubmed
CF mice exhibited significant enrichment of Mycobacteria species and
Bacteroides fragilis , previously associated with
GI infection and immunomodulation . -
pubmed
Antibiotic administration to WT and
CF animals resulted in convergence of their microbiome composition and significant increases in community diversity in
CF mice . -
pubmed
The ability of this approach to finely tune the structural characteristics of chitosan nanocapsules enabled us to systematically investigate the influence of capsule size , wall thickness , and porosity on their efficiency as drug delivery vehicles against
mouse mastocytoma cells after loading them with
curcumin , a natural lipophilic anticancer drug . -
pubmed
BACKGROUND : Muller 's muscle - conjunctival resection is used to correct mild to moderate
ptosis commonly encountered in the rejuvenation
patient population . -
pubmed
METHODS :
Patients who underwent
ptosis correction using Muller 's muscle - conjunctival resection with greater than 10 - month follow - up were included . -
pubmed
On
patients with asymmetric
ptosis , it significantly improved eyelid symmetry to within 1.0 mm from 85 percent of
patients before surgery to 95 percent after surgery , and to within 0.5 mm from 53 percent before surgery to 75 percent of
patients after surgery ( p = 0.036 ) . -
pubmed
Furthermore , the mean correction of
ptosis was not significantly different between medium- ( 1.58 + - 0.93 mm ) and long - term ( 1.32 + - 0.93 mm ) follow - up
patients ( p = 0.258 ) . -
pubmed
( -)- Epigallocatechin-3 - gallate (
EGCG ) , the principal constituent of
green tea , protects neurons from toxic insults by suppressing the microglial secretion of
neurotoxic inflammatory mediators . -
pubmed
Central nervous system ( CNS ) diseases are most widely investigated diseases among all others in respect to the
ginseng 's therapeutic effects . -
pubmed
In this review , we tried to provide comprehensive information on the pharmacological and therapeutic effects of
ginseng and
ginsenosides on neurodegenerative and other
neurological diseases . -
pubmed
Side by side comparison of the therapeutic effects in various
neurological disorders may widen our understanding of the therapeutic potential of
ginseng in
CNS diseases and the possibility to develop not only symptomatic drugs but also disease modifying reagents based on
ginseng . -
pubmed
Age - related
hearing loss patterns in Fischer 344 / NHsd
rats with
cisplatin - induced
hearing loss . -
pubmed
These trials enrolled 1748
periodontitis patients . -
pubmed
Seven trials enrolled
periodontitis patients that were otherwise healthy , 18 trials recruited periodontal patients with various co - morbidities , such as
CVD or
diabetes . -
pubmed
They were randomly classified in two group of
patient - controlled intravenous analgesia for
postoperative pain control , one was group S [ (
sufentanil ) ( n = 30 ) ] and the other was group S + M [ (
magnesium sulphate /
sufentanil ) ( n = 30 ) ] . -
pubmed
CONCLUSIONS : This study showed that
magnesium sulphate added to
sufentanil through
PCIA is an effective method to alleviate
pain in
patients undergoing lower limb orthopedic surgery . -
pubmed
Moreover , we found fewer side effects on
magnesium -
sufentanil regimen in terms of in
nausea ,
vomiting , and sedation ; and
patients ' satisfaction in this regimen was more rather than that in the regiment of
sufentanil alone . -
pubmed
sylvestris extract and compounds 1 , 6 - 8 and 9 were evaluated for antitumor activities against
HepG2 (
human hepatocellular carcinoma ) ,
MG-63 (
human osteosarcoma cells ) ,
B16 (
melanoma cells ) and
HeLa (
human cervical
carcinoma cells ) lines by the
MTT method . -
pubmed
A
patient with a
congenital mucocele diagnosed by prenatal ultrasound screening showing a
cystic lesion of the tongue is presented herein . -
pubmed
METHODS :
Patient characteristics , clinical parameters and laboratory data were retrospectively analysed in
patients with
HSP with or without
nephritis . -
pubmed
RESULTS : A total of 535
patients with
HSP were included in the study . -
pubmed
HSP nephritis occurred in 267
patients ( 49.9 % ) , ranging from isolated
haematuria in 5.2 % , mild
proteinuria in 77.5 % , moderate
proteinuria in 6.4 % and severe
proteinuria in 10.9 % of cases . -
pubmed
The intake of the mainly
plant - derived
n-3 PUFA alpha - linolenic acid (
ALA ) has been reported to be associated with a lower risk of
CHD . -
pubmed
After 3 years number of patients with
AH did not significantly increase , but the structure of the disease changed : number of
patients with stage 2
AH increased and of those with stage 1
AH decreased . -
pubmed
METHODS :
EAE was modeled in
mice and the number of regulatory T cells ( Tregs ) in spleen of
EAE mice was detected by flow cytometry . -
pubmed
We wanted to characterize echocardiographic
LV dysfunction in obese
T2DM subjects as compared to non - diabetic obese controls . -
pubmed
METHODS : One hundred
patients with
T2DM without clinical signs of
heart failure ( 29 % females , mean + - SD age 58.4 + - 10.5 years ,
body mass index (
BMI ) 30.1 + - 5.5 kg / m(2 ) , blood pressure ( BP ) 141 + - 18/83 + - 9 mmHg ) and 100 non - diabetic controls ( 29 % females ) matched for age ( 58.6 + - 10.5 years ) ,
BMI ( 29.8 + - 4.0 kg / m(2 ) and
systolic BP ( 140 + - 14 mmHg ) underwent echocardiography and color tissue Doppler imaging ( TDI ) . -
pubmed
RESULTS :
T2DM patients had more concentric
hypertrophy with a relative wall thickness of 0.42 + - 0.07 vs controls 0.38 + - 0.07 , P & lt ; 0.001 . -
pubmed
The need for a precise diagnostic algorithm is underlined by the awareness that both
ALL therapy and related success rates may vary greatly between
ALL subsets , from standard chemotherapy in
patients with standard - risk
ALL , to allotransplantation ( SCT ) and targeted therapy in high - risk
patients and cases expressing suitable biological targets , respectively . -
pubmed
Radiotherapy is a mainstay for treatment of many
human cancer types , including
head and neck squamous cell carcinoma (
HNSCC ) . -
pubmed
METHODS : Retrospective analysis of
patients with
PSP /
CBD admitted to an inpatient specialized palliative care service . -
pubmed
RESULTS : In 38
patients , there were 63 admissions for swallowing difficulties ,
falls ,
pain ,
impaired communication , cognitive / mood disturbances ,
respiratory symptoms , and
infection . -
pubmed
We present a case of
carcinoma of breast in a 50 - year - old
woman , metastasising to mandibular ramus , condyle and surrounding soft tissue structure presenting as
osteomylitis of condyle . -
pubmed
Mycobacterium tuberculosis , the causative agent of
tuberculosis , remains a leading cause of
human morbidity and mortality worldwide , with approximately 8.6 million cases and 1.3 million
deaths in 2012 . -
pubmed
Cardiac MR enables diagnosis in 90 % of
patients with acute
chest pain , elevated biomarkers and unobstructed coronary arteries . -
pubmed
OBJECTIVE : To assess the diagnostic value of cardiac MRI ( CMR ) in
patients with acute
chest pain , elevated cardiac enzymes and a negative coronary angiogram . -
pubmed
METHODS : This study included a total of 125
patients treated in the
chest pain unit during a 39 - month period . -
pubmed
CMR delivered a correct final diagnosis in 90 % of
patients with acute
chest pain , elevated cardiac enzymes and a negative coronary angiogram . -
pubmed
ADVANCES IN KNOWLEDGE : Diagnosing
patients with
acute coronary syndrome but unobstructed coronary arteries remains a challenge for cardiologists . -
pubmed
Here we show that in budding
yeast Saccharomyces cerevisiae telomere recombination elicits
genome instability and accelerates cellular aging . -
pubmed
To do this , a
rat model of
DM was established by
streptozotocin injection followed by engraftment of autologous jugular veins to carotid arteries to induce
intimal hyperplasia . -
pubmed
Quantitative analysis of high - resolution microendoscopic images for diagnosis of
neoplasia in
patients with
Barrett ' s esophagus . -
pubmed
BACKGROUND AND AIMS : Previous studies show that microendoscopic images can be interpreted visually to identify the presence of
neoplasia in
patients with
Barrett ' s esophagus (
BE ) , but this approach is subjective and requires clinical expertise . -
pubmed
This study describes an approach for quantitative image analysis of microendoscopic images to identify
neoplastic lesions in
patients with
BE . -
pubmed
Primary
wound healing was achieved in all
patients . -
pubmed
Overall
SSTI recurrence rate was 28.0 % ( 95 % CI [ 21.6%-34.4 % ] ) and associated with contact with someone infected with
methicillin resistant
S. - pubmed
METHODS : A total of 207
women with
PCOS and 192 controls were recruited . -
pubmed
[ Evaluation of efficacy and safety of pelvic arterial embolization in
women with primary postpartum
hemorrhage ] . -
pubmed
OBJECTIVE : To evaluate the efficacy and safety of pelvic arterial embolization ( PAE ) in
women with intractable
primary postpartum hemorrhage (
PPH ) . -
pubmed
METHODS : Clinical data of 36 cases were analyzed retrospectively in which
women underwent PAE for intractable primary
PPH in Peking Union Medical College Hospital between Jan 2006 and Jan 2015 . -
pubmed
CONCLUSION :
PAE is a safe and effective treatment for intractable primary
PPH which can prevent hysterectomy and preserve fertility of
patients . -
pubmed
In this review , we provide a perspective and summary of recent advances in the use of
letrozole for
breast cancer in Chinese
patients . -
pubmed
CONCLUSIONS : The rate of incidentally detected
adenocarcinoma prostate in
patients undergoing TURP for clinically diagnosed
BPH was found to be only 5.2 % in our study which is low when compared with similar studies done elsewhere . -
pubmed
Dyscalculia , like
dyslexia , affects some 5 % of school - age
children but has received much less investigative attention . -
pubmed
Role of mir-15a/16 - 1 in early B cell development in a
mouse model of
chronic lymphocytic leukemia . -
pubmed
In both
human chronic lymphocytic leukemia (
CLL ) and the New Zealand Black ( NZB )
murine model of
CLL , decreased levels of microRNAs miR-15a/16 play an important role in the disease . -
pubmed
Furthermore , induced pluripotent stem ( iPS ) cells derived for the first time from NZB
mice , provided insights into the B cell differentiation roadblock inherent in this
strain . -
pubmed
The effect of long - term
amiodarone administration on
myocardial fibrosis and evolution of left ventricular remodeling in a
porcine model of
ischemic cardiomyopathy . -
pubmed
Amiodarone is effective in suppressing
arrhythmias in
heart failure patients . -
pubmed
We investigated the effect of long - term
amiodarone administration on
myocardial fibrosis and
left ventricular ( LV ) remodeling in a
porcine model of
ischemic cardiomyopathy . -
pubmed
Eighteen
infarcted farm
pigs were randomized to receive long - term
amiodarone administration for 3 months ( n = 9 ) or conventional follow - up ( n = 9 ) . -
pubmed
This favorable safety profile suggests that long - term anti -
arrhythmic therapy with
amiodarone warrants further clinical investigation in the subpopulation of
heart failure patients with significantly increased burden of
arrhythmias . -
pubmed
METHODS : Subjects were 123
patients with rectal
cancer undergoing laparoscopic or open total mesorectal excision surgery with preventive ileostomy from 2012 to 2015 . -
pubmed
Abiraterone acetate and
prednisone in chemotherapy - naive
prostate cancer patients : rationale , evidence and clinical utility . -
pubmed
In a phase III trial of
men with asymptomatic or minimally symptomatic , chemotherapy - naive
mCRPC , treatment with oral
abiraterone acetate plus
prednisone led to a statistically significant improvement in the co - primary endpoints of overall survival and radiographic progression - free survival when compared with placebo plus
prednisone . -
pubmed
Ongoing trials are evaluating the role of
abiraterone acetate plus
prednisone in
patients with nonmetastatic
CRPC and
metastatic hormone - sensitive prostate cancer , while further trials in the
mCRPC setting are evaluating its use in combination regimens . -
pubmed
Surgery is usually considered for
patients who have a large
goitre ,
compressive symptoms or significant
ophthalmopathy . -
pubmed
Central
retinal artery occlusion in a 30 - year - old
woman taking
tranexamic acid . -
pubmed
We present a case of a 30 - year - old
woman who suffered a central
retinal artery occlusion while taking
tranexamic acid . -
pubmed
Particularly , the occupancy of g_Pseudomonas , g_Sphingomonas , g_Agrobacterium , g_Achromobacter , and g_Roseateles decreased in
ASD , whereas g_
Streptococcus , g_Akkermansia , g_Rhodococcus , and g_Halomonas increased . -
pubmed
We report a case of
siliconoma with extensive involvement of multiple lymph nodes mimicking malignant features to emphasize that clinicians should carefully evaluate each
patient 's medical history and disease status during differential diagnosis . -
pubmed
The present study utilized the
rat model of mild
andropause to thoroughly evaluate the effects of G and soy extract on the adrenal gland and related blood hormones . -
pubmed
METHODS : Single center , observational , prospective registry of consecutive
patients with
AF , undergoing clinical / echocardiographic evaluation in a University Hospital , as either in - patients or out - patients . -
pubmed
CONCLUSIONS : Risk scores currently adopted for decision making on starting oral anticoagulation provide good prediction of long - term survival in unselected
AF patients , especially in the outpatient setting . -
pubmed
Accordingly , we present a case wherein a
patient with documented
eosinophilia and
heart failure at the age of three - and - a - half years presented with
endomyocardial fibrosis at the age of nine years . -
pubmed
OBJECTIVE : The objectives of this retrospective analysis were to 1 ) report the prevalence of
increased muscle tone in a convenience sample of 128
chronic stroke survivors with moderate / severe motor deficits and 2 ) quantify the relation between tone and motor impairment in
chronic stroke survivors . -
pubmed
The collective
human effort to understand the brain and its common disease ,
stroke , has spanned many centuries , cultures , and societies . -
pubmed
Is echocardiographic epicardial fat thickness increased in
patients with
coronary artery disease ? -
pubmed
Results : This meta - analysis was performed on 13 studies involving 2,436
patients ( 1,622 with
CAD , and 814 without
CAD ) . -
pubmed
The
patients with
CAD had a significantly higher echocardiographic EFT than those without
CAD ( SMD=1.03 , 95 % CI= 0.70 - 1.37 , p=0.000 ) . -
pubmed
More importantly , in a
mouse model of
acute myocardial infarction , the in vivo results of cardiac function , heart morphometry , and immunohistochemistry assessment all confirmed effective heart repair by the PTBC system . -
pubmed
CONTEXT :
Patients with
hypoparathyroidism are treated with
vitamin D and
calcium . -
pubmed
OBJECTIVE : We assessed the efficacy and safety of
alfacalcidol in a large cohort of
patients with
idiopathic hypoparathyroidism (
IH ) and identified a subset who could be treated without oral
calcium . -
pubmed
SUBJECTS AND METHODS : We assessed 92
patients with
IH who were receiving
alfacalcidol and oral
calcium to maintain an optimal serum total
calcium level of 8.0 to 8.5 mg / dL during routine follow - up . -
pubmed
Serum
phosphorus levels normalized when the serum
calcium level increased to 9.9 mg / dL , but this level of serum total
calcium was associated with
hypercalciuria in 90 % of
patients . -
pubmed
However , optimal
calcium control was associated with
hyperphosphatemia and
hypercalciuria in most
patients . -
pubmed
Perennial
canker diseases constitute major threats to the
cherry industry productivity by reducing tree health , longevity , and yields . -
pubmed
Materials and Methods : The data of 137
patients with at least one
thyroid nodule & gt;=2 cm who underwent RFA combined with hydrodissection at our medical center from November 2014 to October 2016 were analyzed . -
pubmed
Only one
patient ( 0.7 % ) experienced
laryngeal nerve injury after operation . -
pubmed
UPLC - QTOF / MS - based metabolomics analysis of plasma reveals an effect of Xue - Fu - Zhu - Yu capsules on
blood - stasis syndrome in
CHD rats . -
pubmed
RESULTS : SPECT showed reversible
ischemia in 36 ( 59 % ) of these 61
patients , and converted to negative in 29 of them . -
pubmed
monocytogenes but not with other Listeria species or
Streptococcus groups A through G. The listeriolysin O latex agglutination assay ( LLOLAT ) was applied to 24 - h and 48 - h USDA primary enrichment cultures of 208 food samples obtained from refrigerators of
listeriosis patients enrolled in a study to determine the role of foods in
sporadic listeriosis . -
pubmed
A 56 - year - old
man who had twice previously undergone orthotopic heart transplantation was admitted with
dyspnea and
heart failure symptoms . -
pubmed
Several months later , the
patient was readmitted with worsening
chest pain and
dyspnea . -
pubmed
We sought to analyze the long - term outcomes of OPCAB versus on - pump coronary artery bypass ( ONCAB ) in
patients with moderate
renal failure . -
pubmed
CONCLUSIONS : OPCAB is associated with improved in - hospital renal outcomes , but is not associated with changes in short- or long - term mortality , or with the long - term cumulative incidence of
end - stage renal failure requiring permanent dialysis in
patients with moderate
renal failure . -
pubmed
Babesia gibsoni is one of the important pathogens causing severe incurable
canine babesiosis , suggesting the necessity to develop a sensitive , specific , and highly automated diagnostic method for clinical application . -
pubmed
RESULTS : The study population included 2382
PCa patients ( mean age 75 years ) . -
pubmed
At initial GnRHa administration , 70 % of
patients neither had lymph node nor distant
metastases . -
pubmed
Extreme responses to immune checkpoint blockade following bipolar
androgen therapy and
enzalutamide in
patients with
metastatic castration resistant prostate cancer . -
pubmed
BACKGROUND : Immune checkpoint inhibition has been shown to have limited efficacy in
patients with
metastatic prostate cancer . -
pubmed
CONCLUSIONS : These cases of
mCRPC suggest that immune checkpoint blockade may have therapeutic potential in
patients with
prostate cancer , especially following immune activation ( " priming " ) using BAT and
enzalutamide . -
pubmed
Cerebral Microbleeds and
Chronic Kidney Disease in
Acute Ischemic Stroke Patients with
Atrial Fibrillation . -
pubmed
BACKGROUND :
Cerebral microbleeds (
CMBs ) are associated with the risk of
intracerebral hemorrhage in
stroke patients with
atrial fibrillation (
AF ) . -
pubmed
We investigated the association between CMBs and
chronic kidney disease (
CKD ) in
patients with
acute ischemic stroke and
AF . -
pubmed
RESULTS : Of the 357 included
patients , 105 ( 29.4 % ) had
CMBs . -
pubmed
CKD ( eGFR & lt ; 60 mL / min/1.73 m2 ) was found in 131 ( 36.7 % )
patients . -
pubmed
Patients with
CKD showed a higher prevalence of any form of
CMB ( 41.2 % versus 22.6 % , P & lt ; .001 ) , deep or infratentorial
CMBs ( 19.9 % versus 9.3 % , P & lt ; .01 ) , and mixed
CMBs ( 14.5 % versus 5.3 % , P & lt ; .01 ) than those without
CKD . -
pubmed
CONCLUSIONS :
CMBs and
CKD are common in
acute ischemic stroke patients with
AF , and
CKD may be a risk factor for
CMBs . -
pubmed
BACKGROUND : Previous studies have been conducted to identify characteristics of
patients with
heart failure with preserved ejection fraction (
HFpEF ) , but the risk factors of
HFpEF remain unclear . -
pubmed
We investigated the associations between arterial stiffness and the risk of hospitalization for
HFpEF patients . -
pubmed
METHODS : For the case group , we enrolled
patients with preserved EF who had been hospitalized for
HF from April 2013 to March 2015 and examined the cardio - ankle vascular index ( CAVI ) . -
pubmed
CONCLUSIONS : The present study has demonstrated that the high value of CAVI was independently associated with the hospitalization of
HFpEF patients . -
pubmed
While
tolypodiol previously showed anti - inflammatory activity in a
mouse ear edema assay , only 2 reduced in vitro
thromboxane B2 and
superoxide anion (
O2- ) generation from
Escherichia coli lipopolysaccharide - activated
rat neonatal microglia to any appreciable degree . -
pubmed
Results : The screening results against various Gram - positive and Gram - negative
bacterial strains revealed that
N -( 2,3 - dihydro-1,4 - benzodioxin-6 - yl )- 4 - methylbenzenesulfonamide ( 3 ) ,
N -( 2 - bromoethyl )- N -( 2,3 - dihydro-1,4 - benzodioxin-6 - yl )- 4 - methylbenzenesulfonamide ( 5a ) and
N -( 2 - phenethyl )- N -( 2,3 - dihydro-1,4 - benzodioxin-6 - yl )- 4 - methylbenzenesulfonamide ( 5b ) showed good inhibitory activity as compared to standard
Ciprofloxacin . -
pubmed
Several vaccine candidates have been introduced for immunization against
Pseudomonas aeruginosa strains . -
pubmed
Due to the rapid increase in several drug - resistant
strains ,
P. - pubmed
Aedes species are common vectors for the clinically important alphaviruses - Chikungunya ,
Sindbis , and Ross River (
RRV ) viruses - with
Aedes aegypti also being a vector for the flaviviruses
dengue , Yellow Fever , and
Zika viruses . -
pubmed
aegypti was putatively implicated in the large 1979 - 1980 South Pacific Islands outbreak of
RRV - the leading cause of
arboviral disease in Australia
today . -
pubmed
A significant decrease in total HO volume in the
rat blast injury model was observed by microCT imaging with no systemic complications following NG-25 therapy . -
pubmed
Single cell RNA - sequencing of
murine cells harvested from the
injury site in a
burn tenotomy
injury model showed increased expression of these genes in MPCs during stages of chondrogenic differentiation . -
pubmed
Comparative study of alterations in phospholipid profiles upon
liver cancer in
humans and
mice . -
pubmed
Comparative studies of molecular alterations upon
cancer between
mice and
humans are of great importance in order to determine the relevance of research involving
mouse cancer models to the development of diagnostic and therapeutic approaches in clinical practice as well as for the mechanistic studies of pathology in
humans . -
pubmed
Out of the 27 common differential signals , six types of phospholipids were also identified to undergo significant alterations in
human serum upon
liver cancer , including PC(34:2 ) , PC(36:4 ) , PC(38:6 ) , PC(36:2 ) , PC(38:4 ) and PC(42:9 ) . -
pubmed
Statistical analysis of the relative intensity distribution of these six identified phospholipids in serum allowed confident determination of
liver cancer in
humans ( sensitivity 91.0 % , specificity 88.0 % , and accuracy 90.0 % ) . -
pubmed
The purified
acarbose was used to evaluate the
hypoglycemia in
streptozotocin (
STZ)-induced
diabetic mice model . -
pubmed
Therefore ,
acarbose from
Actinoplanes hulinensis 1094 could be potentially used to make products for the treatment of
type II diabetes . -
pubmed
Cell populations of
normal and
tumor animals were divided into two groups with equal content of DNA to measure RNA content in either of them . -
pubmed
[ Comparative assessment of
metronidazole and
fasygin in the treatment of
vaginal trichomoniasis in
girls ] . -
pubmed
Xerophthalmia , or
dry eye , is an old
human affliction . -
pubmed
However ,
tetracaine provided a
motor block in a significantly greater number of
patients than did
pubivacaine ( 100 versus 42 % , rho less than 0.001 ) when both drugs were used at the 9.75 - mg dose level . -
pubmed
Seven
patients with reversible
obstructive airways disease , who were unsatisfactorily relieved by conventional bronchodilating drugs , were admitted to a 1 - year - long therapeutic trial with
beclomethasone dipropionate aerosol , 400 mug a day . -
pubmed
With the intention to develop a new concept of venous ultrastructure in
penile venous insufficiency , we studied the histopathology of 13 dorsal penile veins obtained from important
patients during venous ligation because of proven
venous leakage . -
pubmed
To assess the role of altered renal and systemic production of
thromboxane A2 and
prostacyclin in the
hepatorenal syndrome , urinary excretion of their major renal and extrarenal metabolites was measured in
patients with compensated and decompensated
liver disease ,
chronic renal failure , and
hepatorenal syndrome . -
pubmed
Urinary excretion rates of all
prostanoids ( renal and extrarenal ) were increased in
subjects with
liver disease compared with normal controls . -
pubmed
Moreover , they were considerably higher in
subjects with severe
hepatic decompensation but good renal function compared with those with
hepatorenal syndrome . -
pubmed
In contrast , the excretion rate of all metabolites was reduced in
patients with
chronic renal failure . -
pubmed
When corrected for
creatinine clearance , there was a strong correlation between
prostanoid excretion and serum
bilirubin in
subjects with
liver disease ; there was no difference , however , in the excretion of renal and extrarenal
prostanoids between
hepatorenal syndrome and severe
hepatic decompensation . -
pubmed
Detection of
Borrelia burgdorferi in cerebrospinal fluid of
patients with
Lyme borreliosis . -
pubmed
Experiments were undertaken to assess whether pretreatment of
rats with the new
calcium antagonist
anipamil ( 5 mg / kg
body weight , twice daily for 5 days ) protects the isolated heart against a submaximal
calcium paradox . -
pubmed
Conservative surgical treatment in infertile
patients with
endometriosis . -
pubmed
Conditions of chronic use of sunscreens in
human skin , however , are not established but it is possible that , under some circumstances , sunscreen use could enhance
skin cancer risk . -
pubmed
A programme to reduce the risk of
infection by
Echinococcus multilocularis : the use of
praziquantel to control the cestode in a village in the hyperendemic region of Alaska . -
pubmed
This paper reports the results of a 10 - year field trial designed to reduce the risk of
infection by
Echinococcus multilocularis to residents of a village in a hyperendemic area ( Savoonga , St. Lawrence Island ) . -
pubmed
Northern voles ,
Microtus oeconomus , present in the village as commensals , served as an index of risk , as the incidence of
infection in the voles provides information about the availability of eggs within the confines of the inhabited area . -
pubmed
Two
patients with the uncommon finding of involutional
entropion of the upper lid were treated with surgery based on the principles used to treat common lower lid
entropion . -
pubmed
Monoclonal antibodies to
human colorectal epithelium : markers for differentiation and
tumour characterization . -
pubmed
A panel of monoclonal antibodies ( MAbs ) has been obtained , directed against determinants of
normal human colorectal epithelium . -
pubmed
After subplantar administration of the antibiotics pad
edema in
albino rats was observed . -
pubmed
Squamous cell carcinomas in the oral cavity and the oropharynx were diagnosed in 84
patients . -
pubmed
Retrovirus - induced murine
acquired immunodeficiency syndrome : natural history of
infection and differing susceptibility of inbred
mouse strains . -
pubmed
C57BL
mice ( Fv-1b ) develop a severe
immunodeficiency disease following inoculation as adults with
LP - BM5 murine leukemia virus (
MuLV ) , a derivative of
Duplan - Laterjet virus which contains B - tropic ecotropic and mink cell focus - inducing MuLVs and a putative defective genome which may be the proximal cause of disease . -
pubmed
By using this disease profile as a standard , the response of adult
mice of various inbred
strains and selected
F1 hybrids was compared . -
pubmed
Borrelia burgdorferi is transmitted from wild animals to
humans by the
bite of
Ixodes dammini . -
pubmed
All three feeding stages of the tick parasitize
humans , though most
infections are acquired from feeding nymphs in May through early July . -
pubmed
White - footed mice (
Peromyscus leucopus ) are particularly important reservoirs , and in parts of southern Connecticut where
Lyme disease is prevalent in
humans , borreliae are universally present during the summer in these
mice . -
pubmed
dammini are usually indistinguishable , but
strains of
B. - pubmed
Ten
children with recurrent
tracheo - oesophageal fistula have been treated over 13 years ( 1976 - 1988 ) . -
pubmed
The ventricular anti -
arrhythmic action of 20 mg of
betaxolol per day was evaluated in 14
patients treated in monotherapy for a fortnight , by means of repeated Holter recordings . -
pubmed
The Rice-500 Leydig cell
tumor of
Fischer rats is associated with humoral
hypercalcemia in vivo and produces a factor that stimulates
cAMP formation in cultured
rat osteosarcoma cells . -
pubmed
The analysis shows that : ED10/5 yr and ED50/5 yr for 5 X 2.0 Gy / wk is 50 Gy and 65 Gy , respectively , for distinct
telangiectasia ; The latent period , concerning both a certain frequency and degree of reaction , varies exponentially with dose level ; The latent period for 50 % of the
patients , to obtain a certain score , LP50 , is correlated to that for 10 % , LP10 , with LP50 / LP10 = 2.2 + /- 0.2 ( S.D. ) -
pubmed
The fractionation characteristics for
telangiectasia agree well with those for
animal experimental morphological and functional endpoints for late effects in different organs and support the relevance of
telangiectasia as a model for predicting late effects . -
pubmed
The study group consisted of 145
patients who underwent isolated coronary artery bypass grafting between January , 1980 , and July , 1985 , within 4 weeks of an acute
MI . -
pubmed
Postoperatively 38
patients ( 26 % ) had
cardiac failure . -
pubmed
Five
patients , all of whom had postoperative
cardiac failure , died . -
pubmed
The activity of the combination of
pefloxacin with
ceftazidime ,
piperacillin , or
mezlocillin was compared to the activity of the same antibiotics given alone , by measurement of serum bactericidal titres and the rate of killing of ten
strains of
Pseudomonas aeruginosa . -
pubmed
Release of
thromboxane A2 by low - dose
almitrine in the
hypoxic dog . -
pubmed
The low
almitrine dose significantly increased
TXB2 levels in
hypoxic beagles , but the levels remained virtually unchanged in the normoxic
animals with
almitrine bismesylate and in the
hypoxic animals with solvent . -
pubmed
Localized
enamel hypoplasia of the primary
canine . -
pubmed
The lesion , roughly a circular area of
enamel hypoplasia approximately one millimeter in diameter , occurs on the labial surface of the primary
canine tooth . -
pubmed
We used conjunctival impression cytology results to evaluate
children with early
xerophthalmia before treatment and again three to eight weeks later . -
pubmed
We then compared
children with early
xerophthalmia to normal
children . -
pubmed
Conjunctival impressions from
children with
xerophthalmia all showed complete loss of goblet cells and the appearance of enlarged , partially keratinized epithelial cells . -
pubmed
The fluid resuscitation requirements and mortality from
thermal injury were reviewed in 177
children admitted to the Intermountain Burn Center over a 7 year period . -
pubmed
The resuscitative mortality rate for all pediatric
patients was 7 percent , the in - hospital mortality rate was 15 percent , and the 50 percent mortality
burn correlate for these patients was 64 percent of the total body surface area . -
pubmed
Of the 39
deaths observed , 31 occurred in the
patients admitted with
shock . -
pubmed
Retroperitoneal
hematomas in
patients who are in
shock , who have peritoneal irritation or positive peritoneal lavage results , should undergo operation . -
pubmed
Two of the three
patients reported in this study were symptomatic with
blurred vision and systemic complaints . -
pubmed
The
fluorescein angiographic changes observed in the optic disk of
patients with
hypervitaminosis A are similar to those associated with other known causes of
papilledema . -
pubmed
Cardiac responses to autonomic nerve stimulation during
acidosis and
hypoxia in the
lamb . -
pubmed
[ Residual
pulmonary lesions following primary
tuberculosis in
children under the age of 4 and treated with chemotherapy ] . -
pubmed
Infection of chicks with recently isolated
Newcastle disease viruses of low virulence . -
pubmed
This paper reports the clinical and biochemical results in six
patients with
Hurler disease (
Mucopolysaccharidosis IH ; McKusick 25280 ) , two
patients with
Hunter disease (
Mucopolysaccharidosis II ; McKusick 25285 ) and one patient with
Sanfilippo B disease (
Mucopolysaccharidosis IIIB ; McKusick 25292 ) who were treated by fibroblast transplantation . -
pubmed
Intraluminal manometric and cine - cholangiomanometric studies were carried out on the movement of the sphincter of Oddi at the time of excretion of bile into the duodenum in 12
patients after cholecystectomy for
gallstone . -
pubmed
Twenty - one
patients with local
recurrence were treated . -
pubmed
Ten
patients with cutaneous
metastases from head and neck primary
tumors were also treated . -
pubmed
However , these
patients rapidly developed new
tumors in areas adjacent to those previously treated . -
pubmed
[ Transfer of
cefsulodin into
human otorrhea after intravenous administration ] . -
pubmed
Serum from 20
children with
urinary tract infections and proved
cystitis cystica has been examined for antibody to a panel of established cell lines derived from
normal urothelium and
transitional cell carcinomas of the bladder . -
pubmed
Antibody - dependent
cytotoxicity was measured with serial dilutions of
patient serum and lymphocytes from normal healthy
adults as effector cells . -
pubmed
The
patients were grouped according to the duration of symptoms , the presence or absence of reflux , and the presence or absence of upper tract changes or
scarring . -
pubmed
Amyloid fibrils were isolated from the kidneys of two Japanese
patients with
type I FAP and fractionated on Sephadex G-100 gel column . -
pubmed
Angiographically equivocal aneurysmal dilatation at the junction of the internal carotid and the posterior communicating arteries was noted in a
patient with documented
subarachnoid hemorrhage . -
pubmed
The authors report three
children who demonstrated unilateral
displacement of the urinary bladder associated with acute iliofemoral
vein thrombosis . -
pubmed
Acute lymphoblastic leukemia in a
patient with familial derivative chromosome 4 . -
pubmed
To evaluate the possible lack of the elimination of
ischemia with sublingual
nitroglycerin , we studied 25 male
patients with
stable angina pectoris who underwent exercise stress testing with recording of blood pressure ,
pulse , and ST - segment displacement . -
pubmed
All 25
patients had
angina and ischemic ST - segment changes in the first stress test . -
pubmed
On repeat stress testing , 15
patients had
angina and ST - segment changes , 2
patients had
angina but no ST - segment changes , and 4
patients had no ST - segment changes and no
angina . -
pubmed
Four
patients , however , had no
angina but persistent ischemic ST - segment changes suggesting that
angina was converted into silent
ischemia . -
pubmed
Inclusion body myositis developed in two
men , 36 and 48 years old with long - standing common variable
immunodeficiency . -
pubmed
We conclude that inclusion body
myositis can develop in
patients with common variable
immunodeficiency . -
pubmed
Anthelmintic suppression of
Fasciola hepatica infections in
sheep . -
pubmed
In an experiment to examine the use of anthelmintics to suppress the faecal egg output of
Fasciola hepatica from
sheep and reduce the prevalence of
infection on a
sheep farm with a history of
chronic fasciolosis ,
triclabendazole was administered four times annually for three years . -
pubmed
Peripheral blood lymphocytes were obtained from eight untreated
patients suffering from long - standing
plaque - type psoriasis 1 h following UVB treatment and at the end of 15 UVB treatments . -
pubmed
In addition homozygous
mice also demonstrated fasting
hyperglycemia ,
impaired glucose tolerance and reduced fecundity . -
pubmed
Calculating economic
injury levels for
stable flies ( Diptera : Muscidae ) on feeder heifers . -
pubmed
A procedure for calculating the economic
injury levels for
stable flies ,
Stomoxys calcitrans ( L. ) , on feeder heifers was developed from reduction of average daily
weight gain - stable fly population level data in 8 independent replicated experiments over 17 yr . -
pubmed
Recent imaging studies in
patients with
head injury suggest that the development of
traumatic brain oedema may follow a biphasic time course similar to that of
ischaemic oedema . -
pubmed
Human immunodeficiency virus type 1 infection of cells and tissues from the upper and lower
human female reproductive tract . -
pubmed
Viable tissue sections and isolated cell cultures from the
human fallopian tube , uterus , cervix , and vaginal mucosa were examined for susceptibility to
infection with human immunodeficiency virus type 1 (
HIV-1 ) . -
pubmed
We examined infectivity by using the monocytotropic
strain HIV-1(JR - FL ) and several primary isolates of
HIV-1 obtained from infected neonates . -
pubmed
Female reproductive tract cells required a minimum of 60 min of exposure to
HIV-1 in order for
infection to occur , in contrast to peripheral blood lymphocytes , which became infected after being exposed to
HIV-1 for only 1 min . -
pubmed
These findings demonstrate that
HIV-1 can infect cells and tissues from different sites within the female reproductive tract and suggest that multiple cell types , including epithelial cells , may be targets for the initial
infection by
HIV-1 . -
pubmed
Nineteen
patients had a single functioning kidney , 23 had a
bilateral stenosis , which was stented bilaterally in 11 , and 8 had a unilateral
stenosis . -
pubmed
A pronounced
thymic B cell deficiency in the spontaneously
diabetic BB
rat . -
pubmed
Effects of positive feedback on the social interactions of
boys with
attention deficit hyperactivity disorder : a test of the self - protective hypothesis . -
pubmed
METHODS : A total of 12 ELBW
infants ( mean
birth weight , 672 + /- 95 g ; mean gestation , 26 + /- 2 weeks ) served as their own controls in this prospective study comparing physiologic parameters during bottle and breastfeeding . -
pubmed
Decreased serum and intracellular levels of
magnesium have been reported in
patients with
migraine . -
pubmed
We measured ionized
magnesium ,
cyclic AMP (
adenosine monophosphate ) , and
cyclic GMP (
guanosine monophosphate ) in platelets of
patients with
migraine , in
patients with
tension - type headache , and in healthy controls . -
pubmed
The platelet level of ionized
magnesium from
patients with
tension - type headache was significantly lower than the levels from the other two groups . -
pubmed
The platelet level of
cyclic AMP from
patients with
migraine was higher than those from the other groups . -
pubmed
It is suggested that reduced platelet ionized
magnesium in
patients with
tension - type headache is related to abnormal platelet function , and that increased platelet
cyclic AMP in
patients with
migraine is related to alteration of neurotransmitters in the platelet . -
pubmed
It has been reported , however , that a prototype of
dihydropyridines ,
nifedipine , does not reduce mortality of
patients with
ischemic heart disease , possibly because of reflex stimulation of the sympathetic nervous system . -
pubmed
Amlodipine ( 8 mg / kg per day , once a day ) or
nifedipine ( 24 mg / kg per day , three times a day ) was administered to spontaneously
hypertensive 12 - week - old
rats for 12 weeks . -
pubmed
Standardization of the
lactulose -
mannitol test in
rats : application to
burn injury . -
pubmed
These results corroborate those obtained in
burn patients and show that our model is suitable for further experiments on nutritional manipulation . -
pubmed
Over the past decade , various studies have demonstrated that class I antiarrhythmic drugs should be avoided in
patients with
heart failure ,
cardiac ischaemia or a previous
myocardial infarction . -
pubmed
In contrast , class II drugs ( beta - blockers ) reduce morbidity and may even lower mortality in
patients suffering from moderate to severe
heart failure . -
pubmed
If in the setting of
heart failure ventricular arrhythmias are symptomatic and/or sustained ,
patients can be treated effectively , after appropriate treatment of the underlying disease , with the class III drug
amiodarone . -
pubmed
Finally , an implantable cardioverter defibrillator seems to improve overall survival in
patients with life - threatening
ventricular arrhythmias . -
pubmed
Between 1992 and 1996 , 73 acute humeral shaft
fractures in 71
patients were treated with antegrade Russell - Taylor humeral nailing . -
pubmed
Three
patients had preoperative
brachial artery injuries , and 12 had preoperative nerve
palsies . -
pubmed
All
patients without full return of elbow and shoulder function had concomitant
injuries . -
pubmed
Antegrade Russell - Taylor nailing is an acceptable alternative for the treatment of acute
humeral shaft fractures in multiply injured
patients . -
pubmed
The type species of the genus is
Sulfurisphaera ohwakuensis , and the type
strain of the species is TA-1 T (= IFO 15161 T ) . -
pubmed
Metastatic bone disease is a frequent cause of morbidity in advanced
cancer patients with a subsequent high incidence of
skeletal complications (
fractures ,
hypercalcemia ,
spinal cord compression ) and severe
pain . -
pubmed
The aim of this review of the literature is to show the analgesic efficacy of the different
bisphosphonates in phase III studies carried out on
patients with
metastatic bone disease . -
pubmed
From the analysis of the published studies it appears that
bisphosphonates and , in particular , intravenous
Disodium Pamidronate , are not only able to slow down the progression of the disease and to reduce the onset of skeletal complications but also have an analgesic effect and the possibility of improving the quality of life , above all in
patients with
osteolytic metastases due to
breast cancer and
multiple myeloma . -
pubmed
Bisphosphonates represent a further valid therapy to add to an already consolidated list of therapies such as radio , chemo and endocrine therapy , analgesic drugs , orthopaedic and physiatric in the
pain management of
patients with
bone metastases . -
pubmed
It still remains to be seen if the newer and more potent
bisphosphonates such as
Ibandronate and
Zoledronate can be administered differently from the intravenous route such as by mouth or by patch which are readily accepted by the
patient and , moreover , if these more potent drugs are able to prevent or delay the onset and/or the progression of
bone metastases . -
pubmed
On the other hand ,
hypothyroidism may be diagnosed in
patients after
radioiodine therapy , external radiotherapy to the neck and partial or subtotal thyroidectomy . -
pubmed
Between January 1980 and December 1996 , 36
patients with metachronous liver
metastases who underwent hepatic resection were reviewed . -
pubmed
This open study comprised 22
patients with
type I or type II diabetes and 16
patients with leg or
ankle ulcers of different aetiologies . -
pubmed
This study used an
animal model to investigate the importance of the time at which testing occurs for age differences in learning
and memory . -
pubmed
Many
patients treated with breast conservation undergo reexcision to obtain clear margins although the relationship between clear margins and local
recurrence remains controversial . -
pubmed
Reexcision was significantly related to diagnostic method (
spot localization 63 % , excisional biopsy 36 % , fine - needle aspiration 10 % ; P & lt;0.001 ) , first margin status ( clear 0 % , close 11 % , positive 46 % , unknown 48 % ; P & lt;0.001 ) ,
patient age ( 54 years for reexcised
patients and 58 for non - reexcised
patients ; P & lt;0.001 ) , and
tumor size ( mean
tumor size 1 . -
pubmed
Patients undergoing reexcision were significantly more likely to be diagnosed by
spot localization , have nonnegative excisional biopsy margins , be younger , and have smaller
tumors than
patients not undergoing reexcision . -
pubmed
Local
recurrence was not significantly related to margin status ( 8 % with clear margins , 7 % with positive margins , 19 % with close margins , and 11 % with unknown margins ) or reexcision ( 10 % local
recurrence rate for
patients with negative final margins after reexcision and 12 % with positive , close or unknown first margin without reexcision ) . -
pubmed
For
patients with nonnegative margins , reexcision was more commonly performed in young
patients with small
tumors diagnosed by
spot localization biopsy . -
pubmed
Puumala hantavirus (
PUUV ) causes
nephropathia epidemica (
NE ) , a form of
haemorrhagic fever with
renal syndrome that occurs in northern and central Europe . -
pubmed
Alcohol consumption induces hepatocyte apoptosis in
patients with
chronic hepatitis C infection . -
pubmed
The aim of this study was to evaluate the relationship between
alcohol consumption and hepatocyte apoptosis in
hepatitis C - infected patients . -
pubmed
RESULTS : Hepatocyte apoptosis was significantly greater in
hepatitis C - infected
patients than in controls . -
pubmed
CONCLUSIONS : This study confirms that both
hepatitis C infection and
ethanol consumption induce hepatocyte apoptosis in
humans . -
pubmed
Previous studies showed that two groups of
Trypanosoma cruzi clonal genotypes named clonet 20 and clonet 39 were predominant in
Triatoma infestans , the unique vector of
Chagas disease in Bolivia . -
pubmed
We examined sections of brain , spinal cord , spinal roots , and peripheral nerves from a
patient with
paraneoplastic syndrome in the course of
lung adenocarcinoma . -
pubmed
These carnobacteria
strains were also screened for their ability to produce growth inhibitory compounds active against the fish pathogens
Aeromonas salmonicida subsp . - pubmed
METHOD : Thirteen
patients with inoperable
oesophagus cancer were treated between 1995 - 98 . -
pubmed
Side effects :
Oesophagitis of different degree occurred in all
patients , consecutive transitory
dysphagia developed in 9/27 ( 33.3 % )
patients . -
pubmed
OBJECTIVE : The objective was to evaluate prospectively the role of
hyperventilation in the development of
neurocardiogenic syncope in
children during head - upright tilt testing ( HUTT ) . -
pubmed
STUDY DESIGN : Tilt testing was performed in 34
children ( mean age 10.6 years ) with clinical suspicion of
syncope . -
pubmed
RESULTS : Tilt test was negative in 12
cases ; 3 ( 25 % )
patients of this group exhibited
hyperventilation any time during the test . -
pubmed
In the remaining 22 cases the HUTT was positive , and 15 ( 68.2 % )
patients of this group exhibited
hyperventilation at the onset of clinical symptoms and during
syncope . -
pubmed
CONCLUSIONS : Spontaneous
hyperventilation could play a relevant role in the pathophysiology of pediatric
neurocardiogenic syncope , and it could point out a specific subtype of response to orthostatic stress in susceptible
patients . -
pubmed
We suggest the inclusion of capnography in tilt - test protocols could improve the assessment of
syncope in
children . -
pubmed
A total of 69
patients were treated for
ACC from 1955 to 1999 . -
pubmed
One
patient , who presented with fatal
brain metastasis , was excluded from further analysis . -
pubmed
This abnormality , most evident when the system is activated by a low - salt diet , is a cardinal feature of the
syndrome of nonmodulation , affecting a large percentage of white
hypertensive patients . -
pubmed
This study investigated whether young black women are likewise spared its expression or whether the adrenal unresponsiveness common among black
hypertensive patients is unaccompanied by a gender bias . -
pubmed
For this purpose we developed methods to determine the in vitro oxidizability of cerebrospinal fluid and plasma lipoproteins of
Alzheimer patients . -
pubmed
Cerebrospinal fluid and plasma lipoprotein oxidation was found to be increased in
Alzheimer 's
patients compared to controls and a corresponding decrease of antioxidant
vitamins was found . -
pubmed
In a pilot study , in vitro lipoprotein oxidation in cerebrospinal fluid of
Alzheimer patients could be delayed by
vitamin E and C supplementation . -
pubmed
After six weeks , these
mice were challenged with 4T(1 ) and Lewis
cancer cells . -
pubmed
The inhibition of the
tumor and the survival time of the
mice were also investigated . -
pubmed
CONCLUSIONS :
Malignant germ cell tumors arising in the abdomen and retroperitoneum have an excellent prognosis despite advanced stage in most
children . -
pubmed
Analysis of systematic effects on
congenital sensorineural deafness in German Dalmatian
dogs . -
pubmed
We have analysed the systematic influences , phenotypic colour markers and the additive genetic variation for
congenital sensorineural deafness (
CSD ) in German Dalmatian
dogs in order to help elucidate the importance of phenotypic breed characteristics for genetic differences of
CSD . -
pubmed
The heritability estimate for
CSD in German Dalmatian
dogs was h(2)=0.27+/-0.07 . -
pubmed
Levels of enzymes of the direct oxidative pathway of
carbohydrate metabolism in
mammalian tissues and
tumours . -
pubmed
Alpha - Naphthylthiourea (
ANTU ) as a cause of
poisoning in
dogs and its chemical identification in material of animal origin . -
pubmed
RHEUMATIC FEVER IN
CHILDREN AND
ADOLESCENTS . -
pubmed
[ Efficacy of pretreatment with
Serenoa repens on
bleeding associated with transurethral resection of prostate ] . -
pubmed
CONCLUSION : The pretreatment with
Serenoa repens , before TURP procedure , improves the efficacy of the procedure itself and reduces the risk of complications , in particular perioperative
bleeding and duration of postoperative catheterization . -
pubmed
Human studies are needed to evaluate the clinical utility of
rofecoxib treatment in
breast or prostate cancers . -
pubmed
Male
rats exposed for 21 days to high altitude ( 4,340 m ) responded with arrest of
weight gain and increased hematocrit and
testosterone levels . -
pubmed
The present study tested the extension of errorless learning for deficits in social problem - solving skills in
patients with
schizophrenia . -
pubmed
METHOD : Sixty clinically stable
outpatients with
schizophrenia or
schizoaffective disorder were stratified by gender and level of
memory impairment before being randomly assigned to one of two training programs : errorless learning or symptom management . -
pubmed
RESULTS : Paramedics completed 100 MASS assessments for 73 ( 73 % )
stroke /
transient ischemic attack patients and 27 ( 27 % )
stroke mimics . -
pubmed
It distinguishes
stroke mimics , with good recognition of suitable
patients for thrombolytic therapy . -
pubmed
The study was carried out on 92
patients with
otosclerosis , ( 17 M , 75 F ) , median age 41 years ( range 25 - 56 ) , undergoing stapedotomy . -
pubmed
More
patients in the
daclizumab group than in the placebo group died of
infection ( 6 vs. 0 ) when they received concomitant cytolytic therapy . -
pubmed
Despite the availability of several classes of drugs against
acquired immunodeficiency syndrome (
AIDS ) caused by
human immunodeficiency virus type 1(
HIV-1 ) , this deadly disease showing very little sign of containment , especially in Sub - Saharan Africa and South - East Asia . -
pubmed
OBJECTIVE : This study was undertaken to evaluate whether the effects of hyperbaric
oxygen (
HBO ) therapy could alter the critical size for spontaneous healing of a
bone defect in the
rabbit calvarial model . -
pubmed
HBO may have increased the diameter of the
rabbit critical - sized
calvarial defect to more than 18 mm . -
pubmed
PATIENTS AND METHOD : We included a total of 190
diabetic patients from a primary care center , without
coronary heart disease , in whom the coronary risk could be calculated before 1 January 1995 . -
pubmed
Impact of
metabolic syndrome on myocardial perfusion grade after primary percutaneous coronary intervention in
patients with
acute ST elevation myocardial infarction . -
pubmed
AIMS :
Metabolic syndrome with its associated cardiovascular risk factors and prothrombotic , procoagulant and proinflammatory properties and its detrimental effects on coronary microcirculation may play a role in the occurrence of poor myocardial perfusion after primary percutaneous coronary intervention in
patients with
acute myocardial infarction . -
pubmed
Accordingly , this study was designed to evaluate the association between
metabolic syndrome and myocardial perfusion grade in
patients with
acute myocardial infarction undergoing primary percutaneous coronary intervention . -
pubmed
MATERIAL AND METHODS : The study population included 283 consecutive
patients ( 229
men , mean age=62+/-8 years ) admitted to our hospital with
ST - elevation myocardial infarction and who underwent primary percutaneous coronary intervention . -
pubmed
RESULTS : The prevalence of
metabolic syndrome was found to be significantly higher in
patients with poor myocardial perfusion than in those with good myocardial perfusion ( 40 vs. 20 % , respectively , P=0.002 ) . -
pubmed
CONCLUSIONS : We have shown , for the first time , a significant association between
metabolic syndrome and impaired myocardial perfusion after percutaneous coronary intervention in
patients with
acute myocardial infarction . -
pubmed
This data may partially explain the poor short and long - term outcomes of acute
myocardial infarction in
patients with
metabolic syndrome . -
pubmed
Human monocytic ehrlichiosis and
human granulocytic anaplasmosis in the United States , 2001 - 2002 . -
pubmed
The epidemiologic features are described of cases of
human monocytic ehrlichiosis and
human granulocytic anaplasmosis in the United States . -
pubmed
Aerobic bacterial cultures of the tympanic cavity of the middle ear were performed in eight
eastern box turtles (
Terrapene carolina carolina ) with
aural abscesses and 15 eastern box turtles without
aural abscesses ( controls ) that were admitted to The Wildlife Center of Virginia , Virginia , USA during 2003 . -
pubmed
Morganella morganii ( n = 2 ) was the only species isolated from the tympanic cavity of more than one turtle with
aural abscesses . -
pubmed
All nucleotide sequences were homologous to
Rickettsia africae , the agent of
African tick - bite fever (
ATBF ) . -
pubmed
The
purine salvage pathway of
Anopheles gambiae , a mosquito that transmits
malaria , has been identified in genome searches on the basis of sequence homology with characterized enzymes . -
pubmed
PBLs exposed to oxidative stress showed a higher percentage of apoptotic cells in
PD patients than in controls . -
pubmed
However in cells of
PD patients , the increase of apoptotic response was lower than in controls , suggesting that cells of
PD patients have greater " resistance " to oxidative stress . -
pubmed
Morphological alterations in skeletal muscle of spontaneously
hypertensive rats . -
pubmed
Lymphoproliferative disease of
turkeys 1 . -
pubmed
Several outbreaks of a
lymphoproliferative disease of
turkeys were investigated . -
pubmed
Novel vasodilatory effect of intracisternal injection of
magnesium sulfate solution on
spastic cerebral arteries in the
canine two -
hemorrhage model of
subarachnoid hemorrhage . -
pubmed
The present study investigated the effect of intracisternal injection of
MgSO4 solution on
cerebral vasospasm in a
canine model of
subarachnoid hemorrhage (
SAH ) . -
pubmed
METHODS :
Subarachnoid hemorrhage was induced in 10
beagles using the two -
hemorrhage model . -
pubmed
CONCLUSIONS : Intracisternal injection of
MgSO4 solution causes significant dilation of
spastic cerebral arteries in the
canine two -
hemorrhage model of
SAH . -
pubmed
A short note on the identification of the organisms found in
bovine mastitis in U.S.A. -
pubmed
Not without cause :
Vibrio parahaemolyticus induces acute autophagy and cell
death . -
pubmed
Here we discuss possible roles for the induction of autophagy during
infection and discuss how
V. - pubmed
MATERIALS AND METHODS : Within 61 months 39
patients ( 23
male , 16
female , 7 - 53 years , mean 18.7 years , median 17 years ) suffering from
osteoid osteoma were treated . -
pubmed
In 3 of 38
patients relapse occurred after 1 , 14 and 32 months and RFA was repeated . -
pubmed
Uterine adenomyosis in an
orang - utan (
Pongo abelii / pygmaeus ) . -
pubmed
A 48 - year - old , multiparous , female hybrid
orang - utan (
Pongo abelii / pygmaeus ) was investigated after a 3 - year history of irregular and excessively heavy
menstrual bleeding . -
pubmed
There have been few reports of
uterine adenomyosis in non -
human primates and none reported in an
orang - utan . -
pubmed
Uterine adenomyosis should be considered in the differential diagnosis in any multiparous , aged , non -
human female primate with irregular and excessively heavy
menstrual bleeding , and hysterectomy with bilateral salpingo - ovariectomy is recommended as a diagnostic and therapeutic solution . -
pubmed
229
patients underwent follow - up MRI with intravenous contrast , 29 of which showed persistent uptake into
myomata . -
pubmed
Bumetanide delayed the occurrence , and reduced the number of full motor
seizures during kindling , and prevented the development of kindling - induced enhanced
seizure susceptibility in a majority of
animals . -
pubmed
METHODS : Forty - five
patients ( 35
men , age = 62 + /- 15 years ) with
RA atypical
atrial flutter ( n = 15 , group 1 ) , RA
atrial fibrillation (
AF ; n = 15 , no PV initiating foci , group 2 ) , and LA
AF ( n = 1 5 , no RA
arrhythmias , group 3 ) referred for three - dimensional EnSite mapping were included . -
pubmed
The basis of the differential ability of these two
IHNV genogroups to cause disease in
rainbow trout was investigated in live
infection challenges with representative U and M IHNV strains . -
pubmed
Analyses of in vivo replication showed that U IHNV consistently had lower prevalence and lower viral load than M
IHNV during the course of
infection . -
pubmed
We investigated the effects of genetic background on the phenotype of
embryonic lethality that occurs in a
mouse model for
MEN1 . -
pubmed
Thus , an increased level of
D - serine resulting from decreased catalysis corrected the performance of
mice with deficient NMDAR
glycine site activation in behavioral tasks relevant to the negative and
cognitive symptoms of
schizophrenia . -
pubmed
The association between
Streptococcus bovis and bowel
neoplasia has been frequently reported . -
pubmed
These two case reports highlight the possibility of hematogenous seeding of arthroplasty components by
Streptococcus bovis in
patients with
colonic neoplasia . -
pubmed
STUDY OBJECTIVE : The purpose of this randomized controlled trial was to determine the immediate and delayed effects of noninvasive ventilation for
patients in acute
cardiogenic pulmonary edema (
ACPE ) in addition to aggressive usual care in a medical prehospital setting . -
pubmed
METHODS : Out - of - hospital
patients in severe
ACPE were eligible for the study . -
pubmed
boulardii is distributed in lyophilized form in many countries and used for the prevention of
diarrhea in children and adults , including
Clostridium difficile (
C. - pubmed
A hallmark of
inflammation , and a consistent observation in
patients with
ALI , is a perturbation in the systemic redox environment . -
pubmed
Nitrogen - containing
bisphosphonates have been associated with the development of
osteonecrosis of the jaws (
ONJ ) , but the lack of reliable epidemiological data and appropriate
animal models has restricted our understanding of
ONJ pathophysiology and limited its management . -
pubmed
This study investigates the use of
omega-3 fatty acid - enriched lipid emulsions in
ARDS patients and their effects on
eicosanoid values . -
pubmed
METHODS AND
PATIENTS :
Patients ( n = 536 ) with chronic
HF , ejection fraction & lt;50 % and LV end - diastolic volume index & gt;91 mL / m(2 ) , classified according to LV mass index and relative wall thickness ( RWT ) , were followed up for 33 + - 21 months . -
pubmed
CONCLUSION : In
patients with systolic
HF , an independent and incremental risk of adverse outcome was associated with increased mass index and decreased RWT . -
pubmed
Rapid thrombelastography ( r - TEG ) delivers a more comprehensive assessment of the coagulation system but has not been prospectively validated in
trauma patients . -
pubmed
We have evaluated the benefits of a dedicated Pediatric Cardiac Intensive Care Unit ( PCICU ) in the early postoperative outcomes of
patients undergoing surgery for
congenital heart disease . -
pubmed
H1N1 pneumonia : our experience in 50 patients with a severe clinical course of novel
swine - origin influenza A ( H1N1 ) virus ( S - OIV ) . -
pubmed
PURPOSE : The authors reviewed chest radiographs ( CXR ) and thin - section computed tomography ( CT ) findings of pulmonary complications in a selected population of 50 consecutive
patients with severe novel
swine - origin influenza A ( H1N1 ) virus ( S - OIV )
pneumonia who were seen at the Subintensive Respiratory Unit ( UTSIR ) and at the Intensive Care Unit ( ICU ) at Monaldi Hospital , Naples , Italy . -
pubmed
Thoracic comorbidity was present in 18 % of
patients ; 22 % of patients was
obese , and in this group , the clinical course was more aggressive than in the others with the same lesion extent at imaging . -
pubmed
On MDCT , ground - glass opacities and areas of consolidation had a predominant peribronchovascular and subpleural distribution , resembling organising
pneumonia ; they progressed to bilateral extensive
airspace disease in severely ill
patients . -
pubmed
CONCLUSIONS : This case report suggests a new possible syndromic association between
ADEM and
FUO , which should be considered in the clinical examination of
patients with
FUO , especially in the presence of also modest
neurologic or neuropsychiatric symptoms . -
pubmed
The present study used diffusion tensor imaging ( DTI ) to investigate whether occult
brain damage exists in RNMO
patients . -
pubmed
DTI scans using a 3.0 T MRI scanner were performed in 24 clinically confirmed
RNMO patients whose conventional brain MRI results were normal , and also in 24 age- and sex - matched healthy control subjects . -
pubmed
Both acute and stable
NMO patients had a higher average FA in ROIs of the thalamus and putamen . -
pubmed
Acute
NMO patients had significantly higher average MDs than controls in the genu of corpus callosum and optic radiation , and significantly lower average MDs in the medulla oblongata . -
pubmed
Stable
NMO patients had increased MDs in the genu of corpus callosum and optic radiation , but lower MDs in the medulla oblongata , internal capsule and thalamus . -
pubmed
Whey protein enhances normal inflammatory responses during cutaneous
wound healing in
diabetic rats . -
pubmed
Thus , the aim of this study was to determine whether dietary supplementation with WP could enhance normal inflammatory responses during
wound healing in
diabetic rats . -
pubmed
In addition , the time required for
wound healing was significantly prolonged in
diabetic rats . -
pubmed
WP was found to significantly decrease the time required for
wound healing in WDWP
rats . -
pubmed
Optic nerve lesions in
diabetic rats : blood flow to the optic nerve , permeability of micro blood vessels and histopathology . -
pubmed
METHODS : Male
Wistar rats ( n=20 ) were randomly divided into control and
diabetic groups . -
pubmed
RESULTS :
Diabetic rats had atrophic optic nerve fibers with neurite swelling , loss of myelin , and a greater - than - normal proliferation of astrocytes , occurring within 3 months of induction of
diabetes . -
pubmed
Blood flow to the optic nerve was lower in
diabetic rats than in controls . -
pubmed
Microvessel permeability in
diabetic rats increased 2.03 - fold compared to controls . -
pubmed
CONCLUSION :
Diabetic rats develop significant pathological changes in the optic nerve , reduced blood flow to the optic nerve and increase microvessel permeability . -
pubmed
RESULTS :
PCa has been detected in 71 ( 49.3 % )
patients . -
pubmed
Non - dipping pattern in untreated
hypertensive patients is related to increased
pulse wave velocity independent of raised nocturnal blood pressure . -
pubmed
Hypertensive patients were diagnosed according to ambulatory BP measurements ( mean BP & gt;= 130/80 mmHg ) . -
pubmed
Eighty - four
hypertensive patients , consulted for initial evaluation of
hypertension , were enrolled . -
pubmed
Patients with the history of any
cardiovascular disease were excluded from the study . -
pubmed
Palliative and end - of - life care for
patients with
idiopathic pulmonary fibrosis : challenges and dilemmas . -
pubmed
Fifty - five
patients ( seven
men ) had 64
adenomas and 26
focal nodular hyperplasias (
FNHs ) resected . -
pubmed
Impact of
nasal polyps on quality of life of chronic
sinusitis patients . -
pubmed
METHODS : Retrospective analysis of prospectively collected data comparing two groups of
patients diagnosed with
CRS with and without
polyps who underwent surgery with a minimum of 3 month follow up period . -
pubmed
RESULTS : 30
patients underwent surgical management of
CRS over a period of one year . -
pubmed
Polyps were present in 15
patients with
CRS while , the other 15 did not have
polyps . -
pubmed
6
patients required revision surgery ( 20 % ) , 3 ( 10 % ) belonging to
polyp group and 3 ( 10 % ) who did not have
polyps . -
pubmed
CONCLUSION : Nasal
Polyp has a significant negative impact on the
patients with
CRS . -
pubmed
Patients with
polyps have higher symptom scores , worse objective findings compared with patients without
polyp , but patients with
polyp show more improvement after surgical intervention and need for revision surgery is equal in both groups . -
pubmed
VSLI recently received accelerated FDA approval for use in
adults with advanced , relapsed and refractory Philadelphia chromosome - negative
ALL and is in development for untreated adult
ALL , pediatric
ALL and untreated aggressive
NHL . -
pubmed
The Use of NeuroAiD ( MLC601 ) in
Postischemic Stroke Patients . -
pubmed
We aimed to assess the efficacy of MLC601 on functional recovery in
patients given MLC601 after an
ischemic stroke . -
pubmed
This is a retrospective cohort study comparing poststroke
patients given open - label MLC601 ( n = 30 ; 9 female ) for three months and matching
patients who did not receive MLC601 from our
Stroke Data Bank . -
pubmed
Our results show that
HIV-1 infection in Bulgaria reflects the shifting distribution of genotypes coincident with the changing epidemiology of the
HIV-1 epidemic among different risk groups . -
pubmed
Furthermore , the substantial and increasing
HIV-1 genetic heterogeneity , combined with fluctuating
infection dynamics , highlights the importance of sustained and expanded surveillance to prevent and control
HIV-1 infection in Bulgaria . -
pubmed
Differential gene expression related to
Nora virus infection of
Drosophila melanogaster . -
pubmed
Nora virus is a recently discovered RNA picorna - like virus that produces a persistent
infection in
Drosophila melanogaster , but the antiviral pathway or change in gene expression is unknown . -
pubmed
This genome - wide expression profile of
Nora virus infection of
D. - pubmed
Titers to
avian influenza virus antigens increased with age and with geometric mean antibody titer to
human influenza virus antigens . -
pubmed
To verify the usefulness of
8 - OH - Gua , the
8 - OH - dG and
8 - OH - Gua levels in the urine and the
8 - OH - Gua levels in the serum of
type 2 diabetic model
animals , db / db
mice , were measured as oxidative stress markers by a column switching HPLC - system coupled to an electrochemical detector . -
pubmed
Although no difference was observed in the
8 - OH - dG levels in the liver and kidney DNA between the
diabetic and control
mice , these results suggested that urinary
8 - OH - dG and free base
8 - OH - Gua in urine or serum may be good biomarkers of oxidative stress . -
pubmed
Optimal utilization and management of implanted cardiac rhythm devices in
patients hospitalized for
heart failure . -
pubmed
Improved utilization and optimization of device therapy in the management of
patients with decompensated
heart failure (
HF ) is an important clinical priority . -
pubmed
Evaluation and optimization of cardiac resynchronization therapy should be considered in all
patients admitted with
HF despite cardiac resynchronization therapy . -
pubmed
Co - treatment of
rats repeatedly given therapeutic doses of Dcl for 7 days with a single dose of LPS 2h before the last
Dcl dose resulted in severe
liver toxicity . -
pubmed
Thrombus volume is similar in
patients with ruptured and intact
abdominal aortic aneurysms . -
pubmed
The aim of this study was to compare the volume of ILT in
patients with ruptured and intact
AAAs . -
pubmed
METHODS : We matched by maximum axial diameter alone , on a 1:2 basis , 28
patients with ruptured
AAAs and 56
patients with intact
AAAs . -
pubmed
The Mann - Whitney U test was used to compare ILT volumes between
patients with ruptured and intact
AAAs . -
pubmed
PTLD developed in 43
patients ( 1.0 % ) of 4205 pancreas transplants . -
pubmed
Patient survival was significantly decreased in patients with
PTLD , with a one- , three- , and five - yr survival of 91 % , 76 % , and 70 % , compared with 97 % , 93 % , and 88 % in patients without
PTLD ( p & lt ; 0.001 ) . -
pubmed
Patients with the risk factors identified should be monitored closely for the development of
PTLD . -
pubmed
Clinical examination protocol to detect atypical and classical
scrapie in
sheep . -
pubmed
Unless a random sample of the
sheep or
goat population is actively monitored for
scrapie , identification of
scrapie cases relies on the reporting of clinical suspects , which is dependent on the individual 's familiarization with the disease and ability to recognize clinical signs associated with
scrapie . -
pubmed
To aid in the identification of clinical suspects , a short examination protocol is presented to assess the display of specific clinical signs associated with pruritic and nonpruritic forms of
TSEs in
sheep , which could also be applied to
goats . -
pubmed
This may lead to a more detailed neurologic examination of reporting
animals as
scrapie suspects . -
pubmed
It could also be used in experimental TSE studies of
sheep or
goats to evaluate
disease progression or to identify clinical end - point . -
pubmed
Outcome and prognostic factors in
patients with
mantle - cell lymphoma relapsing after autologous stem - cell transplantation : a retrospective study of the European Group for Blood and Marrow Transplantation ( EBMT ) . -
pubmed
BACKGROUND : Autologous stem - cell transplantation ( autoSCT ) is considered a standard treatment of non - frail
patients with
mantle cell lymphoma (
MCL ) , but little is known about outcome of
MCL patients relapsing after autoSCT . -
pubmed
PATIENTS AND METHODS :
Patients with
MCL were eligible if they had relapsed after autoSCT performed between 2000 and 2009 . -
pubmed
CONCLUSIONS :
MCL recurrence within 1 year after autoSCT has an extremely dismal outcome , while the prognosis of
patients with longer remission durations after autoSCT is significantly better . -
pubmed
METHODS : Between April 2003 and April 2011 , 88
patients with small lung lesions which were clinically diagnosed as primary
lung cancer were treated with SBRT . -
pubmed
RESULTS :
Recurrence was observed in 13
patients . -
pubmed
Two
patients ( 2.3 % ) had Grade 2 radiation
pneumonitis , and six
patients ( 6.8 % ) had Grade 2
rib fractures . -
pubmed
A list of the 70 species of Australian ticks ; diagnostic guides to and species accounts of
Ixodes holocyclus (
paralysis tick ) ,
Ixodes cornuatus (
southern paralysis tick ) and
Rhipicephalus australis (
Australian cattle tick ) ; and consideration of the place of Australia in the evolution of ticks with comments on four controversial ideas . -
pubmed
We use an image - matching system much like the image - matching systems of field guides to birds and flowers to identify
Ixodes holocyclus (
paralysis tick ) ,
Ixodes cornuatus (
southern paralysis tick ) and Rhipicephalus ( Boophilus ) australis (
Australian cattle tick ) . -
pubmed
holocyclus (
paralysis tick ) from the first paper on the biology of an Australian tick by Bancroft ( 1884 ) , on
paralysis of
dogs by
I. - pubmed
Limited role of regulatory T cells during acute Theiler virus - induced
encephalitis in resistant C57BL/6
mice . -
pubmed
However , very little is known about the role of Tregs in regulating antiviral responses during
acute encephalitis in resistant
mouse strains . -
pubmed
RESULTS : As expected , DEREG
mice that are on a C57BL/6 background were resistant to
TMEV infection and cleared the virus within days of
infection , regardless of the presence or absence of Tregs . -
pubmed
CONCLUSION : We therefore propose that unlike susceptible
mice strains , interfering with the Treg compartment of resistant
mice only has negligible effects on virus - induced pathologies in the CNS . -
pubmed
Comparison of effect of granules and herbs of Bu - Shen - Yi - Qi - Tang on
airway inflammation in
asthmatic mice . -
pubmed
The aim of this study was to compare the effect of granules and herbs of BSYQT on
airway inflammation in
asthmatic mice . -
pubmed
[ Impairments of
rats ' behavioral reactions , concentration of
corticosterone and expression of cytokine 's gene under experimental
postviral fatigue ] . -
pubmed
OBJECTIVE : We present a clinical and genetic study of four
children of Pakistani descent with similar clinical presentations and treatment course , each of whom suffers from a severe
pustular dermatosis , initially described as a pustular variant of
psoriasis . -
pubmed
MATERIAL AND METHODS : The study sample consisted of 19 drug - free
cluster headache patients ( 16
males , three
females ) and 19 healthy
volunteers . -
pubmed
Dysautonomic symptoms were evaluated during attack and remission periods of
cluster headache patients . -
pubmed
Face sympathetic skin responses might be more sensitive compared to extremity sympathetic skin response in demonstrating
dysautonomic symptoms in
cluster headache patients . -
pubmed
Experimental
microembolism induces localized neuritic pathology in
guinea pig cerebrum . -
pubmed
Microbleeds are a common finding in aged
human brains . -
pubmed
Here we used a
guinea pig model of
cerebral microembolism to explore a potential inductive effect of
vascular injury on neuritic and
amyloid pathogenesis . -
pubmed
These experimental data suggest that
microvascular injury can induce multisystem neuritic pathology associated with an enhanced amyloidogenic potential in wild - type
mammalian brain . -
pubmed
Time - series data were acquired in 58
patients with early to moderate stage
Parkinson ' s disease and 54 healthy controls , and analyzed by Scaled Subprofile Model Principal Component Analysis toolbox . -
pubmed
Of 10,261
patients with
type 2 diabetes who survived to the end of a randomized ADVANCE trial 83 % were included in the ADVANCE - ON project for observation for 6 years . -
pubmed
The results can be related to gradually weakening protective effect of
perindopril /
indapamide combination on cardiovascular system , and are indicative of the expedience of long - term use of this antihypertensive therapy for maximal lowering of mortality of
patients with
diabetes . -
pubmed
METHODS : From a pool of patients with cone - beam computed tomography scans who came for orthodontic treatment , a sample of 133 patients was identified , with 54 in
posterior crossbite ( 28 boys , 26
girls ) and 79 not in
crossbite ( 77 boys , 110 girls ) . -
pubmed
METHODS : A systematic literature review was performed to retrieve randomised controlled trials in
patients with
COPD or
asthma that studied the in - company evolution of inhaler devices . -
pubmed
Metabolomics Identifies Biomarker Pattern for Early Diagnosis of
Hepatocellular Carcinoma : from
Diethylnitrosamine Treated
Rats to Patients . -
pubmed
In addition to glial cells ,
HIV-1 infection occurs in multipotent
human neural precursor cells ( hNPCs ) and induces quiescence in NPCs . -
pubmed
HIV-1 infection of the brain alters hNPC stemness , leading to perturbed endogenous neurorestoration of the CNS following
brain damage by
HIV-1 , compounding the severity of
dementia in adult
neuroAIDS cases . -
pubmed
Relating Histopathology and Mechanical Strain in Experimental Contusion
Spinal Cord Injury in a
Rat Model . -
pubmed
The aim of this study is to determine a relationship between these internal
strains during
SCI and primary damage to spinal cord gray matter ( GM ) in an in vivo
rat contusion model . -
pubmed
Using magnetic resonance imaging and novel image registration methods , we measured three - dimensional ( 3D ) mechanical
strain in in vivo
rat cervical spinal cord ( n = 12 ) during an imposed
contusion injury . -
pubmed
METHODS : We imaged fresh brain slices from 21
MS patients using 1.5 T scanners . -
pubmed
This can be critical for monitoring disease activity and assessing remyelination therapies for
MS patients . -
pubmed
To the best of our knowledge , this is the first case report in the literature of a
patient with
MFH within the abductor pollicis longus ( APL ) muscle . -
pubmed
A 79 - year - old Caucasian
man presented with a
swelling in the middle third of the dorsal aspect of the left forearm . -
pubmed
[ Occurrence and clinical characteristics of
sleep apnea syndrome in
heart failure patients with
atrial fibrillation ] . -
pubmed
OBJECTIVE : To evaluate the occurrence and clinical characteristics of
sleep apnea syndrome (
SAS ) in
heart failure (
HF )
patients with
atrial fibrillation (
AF ) . -
pubmed
METHODS : From
HF patients hospitalized in the First Affiliated Hospital of Nanjing Medical University during June 2012 and June 2014 , subjects were recruited based on electrocardiography examination , including 110
patients with
AF ( coexisting
AF group ) and 105 parallel control
patients without
AF but with matched age , gender and
body mass index ( simple
HF group ) . -
pubmed
Compared with the
patients in simple
HF group , the
patients in coexisting
AF group had a significantly higher Epworth
sleepiness scale score , larger cardiothoracic ratio ( 10.1 + -5.8 vs 8.2 + -5.5 , 0.63 + -0.08 vs 0.57 + -0.07 ; both P<0.05 ) , and shorter 6 - minute walk distance [ ( 305 + -70 ) vs ( 335 + -69 ) m , P<0.05 ] . -
pubmed
CONCLUSION :
HF patients with
AF have a higher frequency of
SAS , more severe
daytime sleepiness and poorer physical activity than matched simple
HF patients without
AF . -
pubmed
Histopathological
thrombus analysis in
patients with
stent thrombosis : what are the missing pieces in the puzzle ? -
pubmed
We aim to measure the incidence of
trastuzumab - related
cardiotoxicity in
patients with early and metastatic
breast cancer in the south of Brazil . -
pubmed
Results Trastuzumab - related
cardiotoxicity was observed in 58
patients ( 53.2 % ) . -
pubmed
Emergency and hospitalization admissions were necessary in seven and three
patients , respectively , due to symptoms of
heart failure . -
pubmed
One
patient died in consequence of
trastuzumab - related
cardiotoxicity . -
pubmed
A 23 - year - old male
patient presented with
headache and
vomiting for 3 - 4 days and
giddiness for 4 - 5 days . -
pubmed
Endoscopic excision of the lesion was done , and the
patient had relief of a
headache and
vomiting immediately after the procedure . -
pubmed
BACKGROUND :
Patients with
non - muscle - invasive bladder cancer (
NMIBC ) belonging to the intermediate - risk group should be treated with intravesical instillations to prevent
recurrence and progression . -
pubmed
There is increasing use of percutaneous interventional techniques for occlusion of
aortic pseudoaneurysms in
patients who are considered unsuitable for surgery . -
pubmed
METHODS AND RESULTS : Retrospective evaluation of the catheter laboratory database was performed at our center and anonymized data was obtained for
patients who had nonstent endovascular treatment of
APAs . -
pubmed
Seven
patients had the combined occlusion and embolization technique , only 1/7 ( 14.3 % ) died from complications related to
APAs . -
pubmed
Methods and results of this study were aimed to inform the implementation of risk - based interventions to better prevent and control
TB at the wildlife - livestock interface , a necessary step for the successful eradication of
TB in
cattle in Spain . -
pubmed
CONCLUSIONS AND RELEVANCE : There was a significant improvement in
depressive symptoms at 6 months after treatment for
patients receiving cochlear implants and hearing aids ; this improvement persisted to 12 months for those who received cochlear implants . -
pubmed
A trial , involving 26 client - owned
dogs with
lameness due to
cranial cruciate ligament failure , was started . -
pubmed
Modified Maquet procedure appears to be an effective treatment for
lameness due to
failure of the cranial cruciate ligament in
dogs . -
pubmed
African green monkeys ( AGM ) and
sooty mangabeys ( SM ) are well - studied natural hosts of
simian immunodeficiency virus (
SIV ) that do not progress to
AIDS when infected with their species - specific viruses . -
pubmed
Costs of providing infusion therapy for
patients with
inflammatory bowel disease in a hospital - based infusion center setting . -
pubmed
Recent research suggests transcranial direct current stimulation ( tDCS ) targeting the dorsolateral prefrontal cortex can potentiate cognitive improvements in healthy
individuals and those with psychiatric conditions , such as
schizophrenia . -
pubmed
Traumatic
injury to the foot and ankle can result in long - term disability , which may have substantial negative implications on a
patient 's functional outcomes and quality of life . -
pubmed
Mite allergoids coupled to nonoxidized mannan from
Saccharomyces cerevisae efficiently target
canine dendritic cells for novel
allergy immunotherapy in veterinary medicine . -
pubmed
farinae allergens coupled to nonoxidized mannan is a novel allergen preparation suitable for
canine allergy immunotherapy targeting dendritic cells . -
pubmed
By means of a double crossover recombination strategy , successfully used for the first time in bifidobacteria , Balat_1410 in the type
strain B. - pubmed
Remarkably , qualitative and quantitative fluorescence analyses demonstrated that the ropy
strain displays a lower capability to adhere to
human intestinal epithelial cells . -
pubmed
In
humans this increases the vulnerability to develop
mental illnesses while in the
rodent brain early life stress ( ELS ) abnormalities are associated with changes in synaptic plasticity , excitability and microstructure . -
pubmed
Detailed information on the effects of ELS on
rodent brain structural integrity at large and connectivity within the brain is currently lacking ; this information is highly relevant for understanding the mechanism by which early life stress predisposes to
mental illnesses . -
pubmed
The aim of this study was to ascertain the response of muscle progenitor cells following
thermal injury in
mice and to enlighten the cellular cascades that contribute to the
muscle wasting . -
pubmed
METHODS : C57BL/6
mice received a 20 % total body surface area ( TBSA )
thermal injury . -
pubmed
Methods : A total of 20
patients with
trichlorethylene - induced
dermatitis who were admitted and treated from January 2014 to October 2016 were enrolled as case group , and 20 persons who underwent physical examination from January to October , 2016 were enrolled as control group . -
pubmed
Percutaneous cryoablation of
breast tumours in
patients with stable metastatic
breast cancer : safety , feasibility and efficacy . -
pubmed
PURPOSE : To evaluate safety , feasibility and efficacy of percutaneous cryoablation of
breast tumours in
patients with clinically stable metastatic
breast cancer , and to compare the findings with reports on alternative procedures , namely surgery and local radiotherapy . -
pubmed
METHODS : 17 female
patients ( average age of 54.8 years + - 10.8 ; range 37 - 72 ) with primary
breast tumour not surgically treated because of metastatic disease were included . -
pubmed
In 15
patients , we obtained a complete regression of the primary
breast lesion without
recurrence during the follow - up period . -
pubmed
Two
patients with lesions measured at 40 and 45 mm had
recurrence in follow up period . -
pubmed
Advances in knowledge : Therapies are limited for these symptomatic
patients at metastatic state of primary
breast tumour . -
pubmed
Approval was based on results from an international , multicenter , multicohort , noncomparative , open - label trial , study BRF113928 , which sequentially enrolled 93
patients who had received previous systemic treatment for advanced
NSCLC ( Cohort B , n = 57 ) or were treatment - naive ( Cohort C , n = 36 ) . -
pubmed
OBJECTIVE : To analyze the clinical features of 6
patients with imported
schistosomiasis mansoni , including the epidemic history , clinical manifestations , laboratory tests and therapeutic effect , so as to provide references for improving the levels of diagnosis and treatment of physicians . -
pubmed
METHODS : The clinical data of 6
patients with imported
schistosomiasis mansoni from January 2009 to July 2016 were collected and analyzed . -
pubmed
RESULTS : All the 6 imported
patients with
schistosomiasis mansoni had a clear history of cercarial infested water exposure . -
pubmed
Hydroperitoneum and
splenomegaly signs were discovered by abdominal ultrasonography in 16.6 % ( 1/6 ) of the
patients . -
pubmed
Colitis was found in all the
patients , and 66.6 % ( 4/6 ) of the
patients were combined with multiple colonic
ulcers by the electronic colonoscopy examination . -
pubmed
Chronic
inflammation and eosinophil infiltration were found in all the
patients by rectum pathology . -
pubmed
No mixture related adverse events (
nausea ,
vomiting ,
pruritus , sedation ,
respiratory depression ) or those related to electrocardiographic parameters (
arrhythmias and
asystole ) were reported in any
patients . -
pubmed
The transport of these metallodrugs by four different hepatopancreatic cell types ( embryonic ( E ) , resorptive ( R ) , fibrillar ( F ) , and
blister ( B ) ) of
U. - pubmed
We investigated the effectiveness of shear wave elastography ( SWE ) in
patients with
lower extremity superficial venous insufficiency ( VI ) . -
pubmed
CONCLUSIONS : In a longitudinal study of
patients with
CKD who subsequently initiated dialysis therapy , LVEF and LVESV worsened and were significantly associated with greater risk for postdialysis mortality . -
pubmed
After a median follow - up of 52 months , a report from the Swedish Multicenter Cohort Study presented a worse
cancer - specific and event - free survival for
patients with
micrometastases than node - negative individuals , but could not demonstrate a significant difference in overall survival ( OS ) . -
pubmed
METHODS : Between September 2000 and January 2004 , 3355
breast cancer patients were included in a prospective cohort . -
pubmed
Patients with
micrometastases received less often chemotherapy than those with macrometastases ( 24.4 vs. 53.9 % ) . -
pubmed
This study demonstrates a similar survival for
patients with
micrometastases and those with macrometastases , possibly due to systemic undertreatment . -
pubmed
One important hallmark of
autoimmune diseases is the detection of autoantibodies in
patient sera . -
pubmed
The muscles of
IMNM patients are characterized by
necrosis ,
atrophy and regenerating fibres with sparse inflammatory infiltrates . -
pubmed
We present a 64 - year - old
patient who developed
agranulocytosis after starting
ATD to treat relapsed
Graves ' disease . -
pubmed
With the growing knowledge on the molecular mechanisms involved in the pathophysiology of
ED , a number of therapeutic gene strategies have been extensively tested and proven to be effective in many
animal models . -
pubmed
Our results suggest that high - risk
patients who have chronic
GVHD or who receive glucocorticoid therapy may require reduced dose of glucocorticoid and long - term physical support to recover physical function after transplantation . -
pubmed
BACKGROUND
Resveratrol , a
polyphenol found on the surface of
red fruits , is able to suppress many kinds of
malignancies . -
pubmed
Pre - clinical development of
Listeria - based nanovaccines as immunotherapies for
solid tumours : insights from
melanoma . -
pubmed
Studies using
mouse models of
subcutaneous melanoma indicated that GNP - LLO91 - 99 nanovaccines recruite and modulate dendritic cell ( DC ) function within the
tumour , alter
tumour immunotolerance inducing
melanoma - specific cytotoxic T cells , cause complete remission and improve survival . -
pubmed
Studies on monocyte - derived DCs from
patients with stage IA , IB or IIIB
melanoma confirmed the ability of GNP - LLO91 - 99 nanovaccines to complement the action of checkpoint inhibitors , by not only reducing the expression of cell -
death markers on DCs , but also potentiating DC antigen - presentation . -
pubmed
The aim of this study was to investigate whether
oral contraceptives ( OC ) use changes the lipoprotein profile associated with disability in
patients with
multiple sclerosis . -
pubmed
Methods : Clinical data was collected from 133 relapsing - remitting
multiple sclerosis (
RRMS )
women with a mean of 6.5 years of disease duration and prior to the start of disease - modifying therapies . -
pubmed
Conclusions : Serum lipid profile is associated with protective effects of
OC use on disability of
RRMS patients . -
pubmed
METHODS : A total of 811
patients with upper gastrointestinal symptoms and histopathological diagnosis of
chronic gastritis were enrolled in the study . -
pubmed
Comment on the article : " Microvascular effects of intravenous
esmolol in
patients with normal cardiac function undergoing postoperative
atrial fibrillation : a prospective pilot study in cardiothoracic surgery " . -
pubmed
Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in
alcohol - induced
hepatotoxicity in
Wistar rats . -
pubmed
Deficiency of programmed cell death 4 affects the balance of T cell subsets in
hyperlipidemic mice . -
pubmed
BACKGROUND :
Depressive symptoms and
impaired physical functioning are prevalent among older
adults . -
pubmed
METHODS : This study was a randomized placebo - controlled trial with 155
participants aged 60 - 80 y who had clinically relevant
depressive symptoms , & gt;=1 functional limitations , and serum
25 - hydroxyvitamin D [
25 ( OH ) D ] concentrations of 15 - 50/70 nmol / L ( depending on season ) . -
pubmed
CONCLUSIONS : Supplementation with 1200 IU / d
vitamin D for 12 mo had no effect on
depressive symptoms and physical functioning in older
persons with relatively low
vitamin D status , clinically relevant
depressive symptoms , and poor physical functioning . -
pubmed
Knee arthroplasty should always be cemented in
patients with known
osteoporosis . -
pubmed
Deregulation of microRNA expression has been shown to play an important role in
human malignancies . -
pubmed
We evaluated ToM in
patients with
schizophrenia spectrum disorders (
SSDs ) , their healthy first - degree relatives , and controls to test its suitability as an endophenotypic marker . -
pubmed
: The sample included 38 stable
SSD patients , 80 unaffected first - degree relatives , and 81 controls . -
pubmed
EGCG , at a concentration of 10 mg / kg , caused behavioral changes in
rats similar to
anxiety . -
pubmed
Our results suggested that the composition of gut microbiota and
anxiety in OVX
rats were simultaneously affected by
EGCG , and therefore , the two conditions might be strongly related , yet the deeper mechanistic links need further exploration . -
pubmed
Triggers and blockers of cirrhotic
cardiomyopathy are poorly understood , which might compromise the prognosis of
chronic liver disease patients . -
pubmed
Ethanol Extract of
Caesalpinia decapetala Inhibits
Influenza Virus Infection In Vitro and In Vivo . -
pubmed
Influenza virus infections can lead to
viral pneumonia and
acute respiratory distress syndrome in severe cases , causing significant morbidity and mortality and posing a great threat to
human health . -
pubmed
The animal study revealed that EEC administration reduces the
weight loss and improves the survival rate of
mice infected with lethal influenza virus . -
pubmed
RESULTS :
Infection was successfully controlled in 48 of 51
patients ( 94.1 % ) ; of these , 24 knees ( 50.0 % ) required no reoperation subsequent to the index KA , whereas the remaining 24 ( 50.0 % )
patients required a median of 1 additional operation . -
pubmed
Nonunion ,
malunion , or delayed union was noted in 10
patients ( 19.6 % ) . -
pubmed
CONCLUSION :
Patients undergoing KA for TKA
PJI had high rates of
infection control and preservation of ambulatory status , with low rates of progression to
AKA in our study . -
pubmed
Methods : Clinical and serological data of 72
CSU patients ( ie , 18 r - CSU and 54 age and sex matched Or - CSU ) were retrospectively collected and analyzed . -
pubmed
All
patients were diagnosed with
CSU for > = 6 months and treated at the Sheba Medical Center during 2013 - 2018 . -
pubmed
Results : Of 289
CSU patients , 18 ( 6 % ) were diagnosed with r -
CSU and treated with the " intensified protocol " including
omalizumab and
cyclosporine - A ( 16p ) ,
methotrexate ( 1p ) , and
azathioprine ( 1p ) . -
pubmed
Emerging preclinical evidence does not support broad use of
hydroxychloroquine in
COVID-19 patients . -
pubmed
Adult
rats , fed long term with
diethylnitrosamine (
DENA , 10 mg / kg / day ) develop
liver carcinoma after 90 days of carcinogen administration . -
pubmed
[ State of circulation in the limbs of
patients with
angiodystonic disorders of vibrational origin ] . -
pubmed
[ Effectiveness of intraoperative cytological examination of peritoneal washings for
patients with
pancreatic cancer ] . -
pubmed
To confirm the effectiveness of cytological examination of peritoneal washings for detecting invisible micro - peritoneal dissemination in
patients with
pancreatic cancer , results were analyzed with the survival and the background factors of the
patients . -
pubmed
Cytological examination of peritoneal washings or ascitic fluid at recto - vesical pouch or pouch of Douglas was performed in 37
patients with primary
pancreatic cancer . -
pubmed
Two of the 8
patients received resection of the
tumor . -
pubmed
Other 6
patients without resection developed clinically evident
peritoneal carcinomatosis . -
pubmed
A high positive rate ( 66.7 % ) of cytological examination of the
patients with visible peritoneal dissemination and a high incidence of appearance of
peritoneal carcinomatosis in patients with positive cytological results but without visible peritoneal dissemination ( 75.0 % ; positive vs 26.1 % ; negative ) indicate a high reliability of the cytological examination to detect invisible micro - peritoneal dissemination . -
pubmed
Estrogen replacement therapy ( ERT ) has been demonstrated to prevent
osteoporosis in postmenopausal
women ( PMW ) . -
pubmed
Reduced concentration of hepatic
alpha - tocopherol in
patients with
alcoholic liver cirrhosis . -
pubmed
The concentration of
alpha - tocopherol was measured in liver biopsy specimens obtained from 83
patients with
alcoholic and non - alcoholic liver diseases . -
pubmed
The mean hepatic
vitamin E content ( as
alpha - tocopherol ) was significantly lower in 23
patients with
alcoholic cirrhosis ( 17.6 + /- 12.1 nmol / mg wet weight liver ) , compared with 12
patients with normal liver histology ( 39.2 + /- 29.7 nmol / mg , P less than 0.01 ) . -
pubmed
The mean serum concentration of
alpha - tocopherol was lower in
patients with
alcoholic cirrhosis ( 13.9 + /- 7.0 mumol / l ) than in
individuals with
alcoholic fatty liver ( 21.3 + /- 9.3 mumol / l , P less than 0.01 ) and
patients with normal liver histology ( 23.4 + /- 11.6 mumol / l , P less than 0.01 ) . -
pubmed
A decreased ratio of serum
alpha - tocopherol / total serum lipids was also observed in
patients with
alcoholic cirrhosis , compared with
patients with normal liver histology ( P less than 0.05 ) . -
pubmed
Similarly , the primary
tumors of
patients with
skeletal metastasis contained considerably less enzyme activity compared with those of
patients surviving without skeletal
metastasis . -
pubmed
Degree and duration of
bronchial hyperreactivity ( BHR ) after environmental tobacco smoke ( ETS ) inhalation was assessed in 31 smoke - sensitive
subjects with
asthma who exhibited lower airway symptoms on
ETS exposure ( group I ) and 39 smoke - sensitive subjects without
asthma who manifested only
upper airway symptoms on cigarette - smoke exposure ( group II ) . -
pubmed
Partial obstruction of the
opossum esophagus leads to thickening of the circular muscle ,
hypertrophy of smooth muscle cells , and diminution of the extracellular space . -
pubmed
Each of these chemicals had been reported positive in the Ames test and/or the
mouse lymphoma TK+/- mutation assay . -
pubmed
This chemical has been shown recently to cause various
tumors in
rodents . -
pubmed
Longitudinal electroretinogram study in a
patient with
metallosis oculi . -
pubmed
Serial electroretinograms were obtained from a
patient with
visual loss secondary to an intraocular metallic
foreign body . -
pubmed
An epidemiological study on occupational acute
pyrethroid poisoning in
cotton farmers . -
pubmed
A cross sectional survey on the prevalence of acute
pyrethroid poisoning in
cotton farmers was conducted in 1987 and 1988 . -
pubmed
Properties of macrophages from high- and low - responder
strains of
mice . -
pubmed
Direct diffusion of
cis - diamminedichloroplatinum ( II ) in intraperitoneal
rat tumors after intraperitoneal chemotherapy : a comparison with systemic chemotherapy . -
pubmed
We have developed a
rat tumor model in which penetration and distribution of
cis - diamminedichloroplatinum ( II ) into intraperitoneal
tumors have been studied . -
pubmed
Factors affecting the clinical response to treatment with
digoxin and two
calcium antagonists in
patients with
atrial fibrillation . -
pubmed
Sexual function was studied in 15
males with
myotonic dystrophy . -
pubmed
Bacteriological effects of anti -
Pseudomonas aeruginosa chemotherapy in
cystic fibrosis . -
pubmed
Strains of
Pseudomonas aeruginosa resistant to clinically relevant antibiotics (
beta - lactams ,
quinolones ,
aminoglycosides ) were detectable in sputa of
cystic fibrosis patients . -
pubmed
Ambulant , transcutaneous PCO2 monitoring has been used to show that
hyperventilation precedes exacerbation of
asthma in a
patient . -
pubmed
Conduction in the central motor pathways was studied in 9
patients with
cerebrovascular disease (
CVD ) , 13 with
amyotrophic lateral sclerosis (
ALS ) and 3 with
spinal progressive muscular atrophy (
SPMA ) . -
pubmed
In
patients with
CVD , responses to cortical stimulation were unobtainable or delayed in the paretic limb muscles . -
pubmed
In
patients with
ALS the abnormality of central motor conduction had significant correlation with the extensor plantar response . -
pubmed
By comparative sonographic and myelographic investigations of 61
patients with
lumbar disc herniations and other
nerval compressive syndromes , the value of the spinal sonography in the diagnosis of
lumbar disc herniation is demonstrated . -
pubmed
Clinical features , diagnostic procedure , therapy , course of the disease and prognosis in 6
patients with severe idiopathic
chronic cold agglutinin disease are described . -
pubmed
In 5
patients the main complaint was cold mediated
acrocyanosis . -
pubmed
One
patient developed a
lymphoproliferative disorder 11 years after diagnosis of
idiopathic chronic cold agglutinin disease . -
pubmed
Fifteen
patients with
congenital ptosis with a varying amount of levator action were operated on with this technique . -
pubmed
A
human KB carcinoma cell line and a
Chinese hamster ovary cell line selected for crossresistance to multiple chemotherapeutic agents , including most antimitotic drugs , are sensitive to
DCBT . -
pubmed
Cell - mediated immune responses to
influenza virus antigens expressed by
vaccinia virus recombinants . -
pubmed
These recombinant viruses together with a recombinant expressing the HA from
influenza virus A / JAP / 305 / 57 ( H2N2 ) have been used to examine the cytotoxic T lymphocyte ( CTL ) response to these
influenza virus antigens . -
pubmed
[
Tremor development in
dogs caused by stimulation of the dorsal hippocampus ] . -
pubmed
The triphasic response of the isolated superior cervical
ganglion of the
rat to cholinergic stimulants . -
pubmed
[ The transforming effect of blood from
leukemic patients on a culture of
human diploid cells ] . -
pubmed
[ Histological study of experimental
autolysis of the striated muscle of the
guinea pig ] . -
pubmed
Grades of atypia in tubular and villous
adenomas of the
human colon . -
pubmed
Of a total of 544 tubular , villous and tubulo - villous
adenomas of the
human colon which were investigated by light microscopy , six tubular and six villous
adenomas were examined under the electron microscope . -
pubmed
Twenty - two
patients with advanced stage
germ cell carcinomas received a combination chemotherapy regimen of
cis - platinum ,
vinblastine ,
bleomycin and
actinomycin D. -
pubmed
Only one
relapse has occurred among the former group with 82 % alive and disease - free with follow - up of 27 - 50 months , indicating the majority of these
patients may be cured . -
pubmed
Management of advanced stage
germ cell carcinoma can now be considered highly successful although further studies are needed to determine optimal treatment for
patients with bulky disease and the role , if any , of maintenance therapy . -
pubmed
[ Effect of
levamisole on peripheral blood neutrophils in
patients with
neoplasms ] . -
pubmed
The history of a
patient with two
thoracoabdominal aneurysms and
lumbar Pott ' s disease is reported . -
pubmed
In the postoperative course the
patient experienced acute
low back pain . -
pubmed
The incidence over 7 days of isotopically - detected calf and popliteal vein
thrombosis was determined in a group of 60
diabetic patients admitted to hospital with
myocardial infarction ,
heart failure or
stroke , or for abdominal surgery . -
pubmed
Metabolic and clinical disturbances in
patients with
calcium urolithiasis . -
pubmed
Human brucellosis in the Negev region of Israel , 1981 . -
pubmed
High levels of
LA were also found in the pleural fluid of 15
patients with
malignancy of pleural cavity . -
pubmed
A
patient with several episodes of
jaundice associated with
sulfamethoxazole therapy is described . -
pubmed
After an injection of
fluorescein , levels of
fluorescein in the vitreous humor are reported to be elevated in
diabetic patients compared with controls even when there is no retinal pathologic condition discernible by angiography or ophthalmoscopy . -
pubmed
An analysis of 245
children with
hypertension seen in 3 years in the Southern Railway Hospital , Madras is presented . -
pubmed
[
Hypertensive pulmonary vascular disease in
children . -
pubmed
In the past , in countries where
otitis media is usually treated , complications have been rare , because of the good activity of almost all orally administered antibiotics against the most common cause of complications ,
Streptococcus pneumoniae . -
pubmed
A proportion of
rats exposed to inescapable tailshock stress displayed a performance deficit , termed
learned helplessness , in a subsequent shuttlebox avoidance task . -
pubmed
Following an exposure to a milder form of inescapable
shock , an increase in
norepinephrine output was detected in learned helpless
rats , which was significantly greater than nonhelpless , nonprestressed , or control
animals . -
pubmed
Therefore , the possibility exists that similar neurochemical changes may also be responsible for some of the symptoms of
human posttraumatic stress disorder (
PTSD ) , such as the poor coping associated with seemingly mild stress . -
pubmed
Acute
inflammation in foetal and adult
sheep : the response to subcutaneous injection of turpentine and carrageenan . -
pubmed
Because of the small number of inflammatory cells found in skin
wounds , it has been considered that foetal
sheep are incapable of an adequate inflammatory response . -
pubmed
Nerve blood flow , reflected by laser Doppler flow measurements , and motor nerve conduction velocity were both significantly less in
diabetic than in control
animals . -
pubmed
Thirty - eight
patients ( 16 males and 22 females ) with
mediastinal cysts have been treated at the Second Department of Surgery at Okayama University from 1978 to 1989 . -
pubmed
Baclofen administration for the treatment of
affective disorders in alcoholic
patients . -
pubmed
Ninety alcoholic
patients with the secondary
affective disorders (
anxiety ,
depression ) were divided into four groups . -
pubmed
The results of clinical , psychological ( tests of Spielberger , Zung and MMPI ) , and electrophysiological ( superslow omega - potential ) investigations showed that
baclofen is an effective drug for
affective disturbances in alcoholic
patients , with efficacy superior to placebo and equal to
diazepam and
amitriptyline . -
pubmed
The peripheral matabolism of
GABA and
monoamines do not seem to be related to the development of secondary
affective disorders in alcoholic
patients . -
pubmed
To determine the role of animals as possible sources for
human infection with
Campylobacter jejuni / coli , 218
human cases of
Campylobacter enteritis diagnosed among members of Group Health Cooperative of Puget Sound , King County , Washington , from April 1982 through September 1983 were compared with 526 controls , randomly selected from Group Health Cooperative members . -
pubmed
To prove the hypothesis that cardiopulmonary bypass may accelerate the development of
acquired immunodeficiency syndrome (
AIDS ) in the
human immunodeficiency virus carrier , the clinical course of 40
patients positive for
human immunodeficiency virus who underwent cardiac operations between 1986 and 1992 was analyzed , especially in regard to the progression to
AIDS . -
pubmed
Valve procedures were performed in 38
patients ( 95 % ) , mostly for
endocarditis in drug addicts . -
pubmed
Four
patients ( 12.5 % ) experienced progression to
AIDS during the follow - up period . -
pubmed
The majority of
strains of the main causative agent ,
Aspergillus fumigatus , produce
gliotoxin , a secondary metabolite with demonstrated in vitro immunosuppressive activity . -
pubmed
Pretreatment of normally resistant
mice with a single injection of a sublethal dose of
gliotoxin was sufficient to make them susceptible to
infection and subsequent
death , after challenge with
A. - pubmed
PURPOSE : This report describes a female
infant with stage 4 multifocal
ganglioneuroblastoma with gastric involvement . -
pubmed
PATIENT : The
patient had a
right cervical tumor , a left
posterior mediastinal tumor , bilateral
adrenal tumors , and bony and bone marrow
metastases . -
pubmed
The latter mechanism may have accounted for our
patient 's
gastric tumor . -
pubmed
Patients with
multifocal ganglioneuroblastomas warrant meticulous radiographic and surgical evaluation to completely document the full extent of disease , and to ensure appropriate staging and therapy . -
pubmed
Effect of six - month treatment with
Ukrain on early
osteoporosis induced by ovariectomy in
rats . -
pubmed
A retrospective study was performed to determine whether there is an increased incidence of
hyperglycemia in
patients not predisposed to
hyperglycemia ( n = 102 ) who receive total parenteral nutrition ( TPN )
dextrose in excess of 4 to 5 mg / kg / min . -
pubmed
Of the 37
subjects administered
dextrose at & gt ; 5 mg / kg / min , 18 exhibited
hyperglycemia . -
pubmed
OBJECTIVES : Following an outbreak of
tuberculosis (
TB ) among health care workers at a public hospital , the study was undertaken to ( a ) locate all exposed patients and administer tuberculin skin tests ( TSTs ) to them , ( b ) provide clinical treatment or prophylaxis to infected patients , and ( c ) ascertain the risk of
M. - pubmed
In all , 362 patients ( 72 % ) were lost to follow - up , including many
HIV - positive and homeless patients , who are at high risk of developing active
TB once infected with
M. - pubmed
In the present study we have found a similar synergistic interaction between
exifone and
ascorbic acid (
vitamin C ) against both
chloroquine - susceptible and multidrug - resistant
strains of
Plasmodium falciparum . -
pubmed
Morris water maze deficits in
rats following
traumatic brain injury : lateral controlled cortical impact . -
pubmed
Adult
rats were subjected to one of two different levels of
cortical injury , mild ( 1 mm ) or moderate ( 2 mm ) deformation , and subsequently tested for their ability to learn ( acquisition ) or remember ( retention ) a spatial task , 7 or 14 days after
injury . -
pubmed
Results revealed an
injury - dependent deficit for experimental
animals compared to sham - operated controls . -
pubmed
This study was carried out to investigate the immunological status of 50 transfusion - dependent
children with
beta - thalassaemia , taking into account that lymphocyte characteristics are affected by sex , age and race . -
pubmed
RESULTS : The normal Chinese
children had higher NK levels than the
beta - thalassaemia children . -
pubmed
BACKGROUND : The effects of simulated "
ischemia " and " reperfusion " were evaluated in cell cultures of
human ventricular cardiomyocytes and
human saphenous vein endothelial cells . -
pubmed
3 - Hydroxybutyrate aids the recovery of the energy state from aglycaemic
hypoxia of adult but not neonatal
rat brain slices . -
pubmed
Gastroesophageal reflux and a comparison of the different antireflux procedures following esophagomyotomy : an experimental study in
rabbits . -
pubmed
PATIENTS AND METHODS : Thirty - one eyes of 28 consecutive
patient who underwent AK for excessive postkeratoplasty
astigmatism were studied . -
pubmed
Cardiac parasympathetic stimulation via QRS - synchronous low - energy
shocks in
humans . -
pubmed
INTRODUCTION : In
patients receiving test
shocks to verify lead connections at implantation , we anecdotally have observed postshock delay . -
pubmed
Each
patient received QRS - synchronous
shocks of 0.2 , 0.4 , 0.6 , and 2.0 J in random order . -
pubmed
Patients were further randomized to receive either saline or 2.0 mg
atropine intravenously , and then given a second sequence of
shocks . -
pubmed
CONCLUSION : Low - energy
shocks delivered during the QRS complex cause postshock cycle length prolongation in
man . -
pubmed
A total of 103
patients comprising 95
squamous cell carcinomas , 3
adenosquamous cell carcinomas and 5
adenocarcinomas , were studied . -
pubmed
The positivity of the
patients with abnormal sr - SCC levels for
squamous cell carcinoma ,
adenosquamous cell carcinoma and
adenocarcinoma were 87.7 % , 50.0 % and 40.0 % , respectively The 5 - year - survival rates of sr - SCC positive and negative
patients were 71.1 % and 100 % , respectively ( P & gt ; 0.1 ) . -
pubmed
The positivity of
patients with im - CA19 - 9 in
squamous cell carcinoma ,
adenosquamous cell carcinoma , im - CA19 - 9
adenocarcinoma were 29.1 % , 66.6 % , and 100 % , respectively . -
pubmed
These results suggested that follow - up of
patients by periodical serum examination for these
tumor markers is highly useful for the early detection of
tumor relapse . -
pubmed
These are absorbtion of
bacteria and their toxins from peritoneum , phagocytosis , opsonization , activation of the complement and separation of
infection in the peritoneal cavity . -
pubmed
This phase I study was undertaken to define the maximum tolerated dose ,
dose - limiting toxicity , and recommended dosage of
UFT (
uracil and
tegafur ) plus oral
calcium folinate (
Orzel ) and
vinorelbine (
Navelbine ) in combination treatment of metastatic
breast cancer in
patients who have received one prior chemotherapy regimen . -
pubmed
The effect of
butylated hydroxytoluene on selected immune surveillance parameters in
rats bearing enzyme - altered
hepatic preneoplastic lesions . -
pubmed
A lag in time needed to attain maximum
calcium release was observed only in the
rats with
PH compared with those without PH . -
pubmed
Further investigations are necessary to determine whether the observed suppression of NK cell activity during EAF induction and growth modulation by
BHT is a contributing factor in enhancement of
rodent liver neoplasia by this non - genotoxic food antioxidant . -
pubmed
Liver scintigraphy is useful for selecting candidates for preoperative transarterial chemoembolization among
patients with
hepatocellular carcinoma and
chronic liver disease . -
pubmed
BACKGROUND : The indications for preoperative hepatic transarterial chemoembolization ( TACE ) have not been clarified by recent studies in
patients with
hepatocellular carcinoma (
HCC ) complicated by
chronic liver diseases . -
pubmed
PATIENTS AND METHODS : Liver scintigraphy was performed before and several weeks after TACE in 64
patients with
HCC complicated by
chronic hepatitis or
cirrhosis . -
pubmed
Three major
postoperative complications occurred in
patients with LHL15 & gt ; or = 0.91 , and no major complications occurred in
patients with LHL15 & lt;0.91 . -
pubmed
CONCLUSIONS : The results suggest that preoperative TACE should be performed in
HCC patients only when LHL15 is less than 0.91 , and that preoperative TACE is not an appropriate treatment for
patients with LHL15 & gt ; or = 0.91 when
HCC is resectable . -
pubmed
The total number of complications was 0.24 episodes per
patient per year at risk and the rate of
thrombosis 0.1 . -
pubmed
Patients with
glomerulonephritis had the best function rates for their VA , the median exceeding the duration of the study , whereas in half of the
diabetic patients it was less than 1 year . -
pubmed
Three
patients in this group had postoperative
stroke . -
pubmed
Total 10
patients ( 2.1 % ) sustained
neurological complications . -
pubmed
We report on a 75 - year - old female
patient who developed several
thermal keratoses and
squamous cell carcinomas at the site of
erythema ab igne caused by chronic heat exposure over several years . -
pubmed
Larval growth of
Diaprepes abbreviatus ( Coleoptera : Curculionidae ) and resulting
root injury to three citrus varieties in two soil types . -
pubmed
Larval growth and intraspecific competition of
Diaprepes abbreviatus ( L. ) larvae and consequent
root injury in container - grown citrus in the greenhouse were evaluated . -
pubmed
Although not statistically significant ,
root injury developed slightly slower on
Swingle citrumelo compared with Carrizo and Cleopatra rootstocks , but damage was comparable by 79 d. Little or no difference in consumptive benefit to the larvae was found between the rootstocks . -
pubmed
Thallium-201 myocardial SPET in
patients with
collagen disease . -
pubmed
We analysed stress
201Tl myocardial single photon emission tomography ( SPET ) in
collagen disease patients to evaluate abnormal uptake patterns and their clinical significance in the assessment of the cardiac status of these
patients . -
pubmed
Twenty - two
collagen disease patients ( 13 with
progressive systemic sclerosis (
PSS ) and nine with
systemic lupus erythematosus (
SLE ) ) were examined by
201Tl myocardial SPET with exercise ( n = 9 ) or
dipyridamole stress ( n = 13 ) . -
pubmed
Patients were divided into two groups : those with
cardiac abnormalities on conventional testing ( Group A , n = 10 ) and those without ( Group B , n = 12 ) . -
pubmed
High - risk groups for
hepatitis C virus infection included recipients of blood transfusion of which the blood donors were not screened for anti -
HCV , intravenous drug abusers ,
hemophiliacs , and patients who have received hemodialysis . -
pubmed
Hepatitis C virus was the most common cause of
chronic hepatitis ,
cirrhosis , and
hepatocellular carcinoma in Western countries and in Japan , where
hepatitis B virus is not endemic . -
pubmed
However , the
relapse rate was high and only 20 % to 25 % of
patients sustained response 1 year after discontinuing therapy . -
pubmed
Role of
budesonide inhalation suspension in
children with
asthma . -
pubmed
OBJECTIVE : To evaluate the role of
budesonide inhalation suspension ( BIS ) in the treatment of
children with
asthma . -
pubmed
DATA SYNTHESIS :
Asthma is a
chronic inflammatory disease that affects approximately 4.8 million
children in the US . -
pubmed
As the first nebulized
corticosteroid , BIS offers an important treatment option for
children with persistent
asthma . -
pubmed
CONCLUSIONS :
BIS is effective in reducing symptoms and improving lung function in
children with
asthma . -
pubmed
It should be used in
children ages 1 - 8 years with moderate to severe persistent
asthma who are unable to effectively use a metered - dose inhaler with or without a spacer or a dry - powder inhaler . -
pubmed
Diet enriched with
omega-3 fatty acids alleviates
convulsion symptoms in
epilepsy patients . -
pubmed
PURPOSE : We examined whether a dietary supplement containing
omega-3 polyunsaturated fatty acids (
n-3 PUFAs ) can alleviate and/or reduce the frequency of
epileptic seizures in
patients with
central nervous system ( CNS ) diseases treated with anticonvulsive drugs ( ACDs ) . -
pubmed
METHODS : The records of 27
patients ( 30 eyes ) having undergone orbital decompression of one wall , two walls and three walls for severe
thyroid orbitopathy were analyzed for changes in visual acuity , visual field or pattern visual evoked potential , movement and reduction in
proptosis . -
pubmed
CONCLUSION : Orbital decompression is effective in improving vision in most
patients with severe
thyroid associated ophthalmopathy , and the
proptosis can be effectively improved . -
pubmed
Toward a better understanding of light - induced
photoreceptor damage , the crystallin content of
rat retina was examined following intense light exposure . -
pubmed
Repetitive R(int ) measurements were performed in 125 healthy
children and 107
asthmatic children ( age range 0.8 - 16.8 years ) . -
pubmed
The absence of effect of
cortisone therapy upon plasma lipid levels in
patients with
rheumatoid arthritis . -
pubmed
Valid and reliable measurements of
muscle impairment are needed to assess therapeutic efficacy in
patients with generalized
myasthenia gravis . -
pubmed
A Pugh score of 8 adequately selects
patients with parenchymal
cirrhosis for liver transplantation . -
pubmed
The aim of our study was to develop simple and highly effective scores to estimate prognosis at 1 year for
patients with parenchymal
cirrhosis and to define the optimum time for liver transplantation with the same degree of accuracy as the prognosis estimation for
primary biliary cirrhosis . -
pubmed
The prognostic value of 19 variables was studied retrospectively in 91
patients with parenchymal
cirrhosis using multivariate analysis and logistic regression . -
pubmed
The prognostic value of a Pugh score & lt ; or = 8 or & gt ; 8 was confirmed in a prospective study of 145
cirrhotic patients with 78 % correct prediction . -
pubmed
During this period , 21
patients with parenchymal
cirrhosis received transplants with a preoperative Pugh score of 9.5 + /- 2.0 ( mean + /- SEM ) and 60 % 1- and 2 - year survival . -
pubmed
Although successful and persistent colonization of the gastric mucosa depends on the ability to respond to changing environmental conditions and co - ordinate the expression of virulence factors during the course of
infection ,
Helicobacter pylori possesses relatively few transcriptional regulators . -
pubmed
STUDY DESIGN : Thirteen
patients underwent intraoperative RF to treat
tumors closer than 6 mm to a central bile duct . -
pubmed
Twelve
patients ( 92.3 % ) did not present any
biliary stenosis . -
pubmed
In one
patient ( 7.7 % )
biliary stenosis was detected 6 months after RF . -
pubmed
The
patient was
cirrhotic but did not require any treatment . -
pubmed
One of the 13
patients had a local
recurrence . -
pubmed
In
patients with
RCC dielectric permittivity of
tumor tissue was 1.43 + /- 0.39 times greater than that of surrounding normal parenchyma ( p & lt ; 0.001 ) . -
pubmed
Modified mutation method for screening low
citrinin - producing
strains of
Monascus purpureus on
rice culture . -
pubmed
Monascus purpureus NTU 601 is a
strain that produces
monacolin K ,
gamma - aminobutyric acid (
GABA ) , and
citrinin under solid culture conditions . -
pubmed
Because
citrinin is a mycotoxin and possesses
nephrotoxic and
hepatoxic effects , it has a negative impact on the acceptance of red mold
rice by people . -
pubmed
In this research , a simple and quick selection method for mutant
strains with low
citrinin production was designed based on the fact that
citrinin possesses antibacterial activity for
Bacillus subtilis and will form an inhibition zone around the colony of the Monascus
strain . -
pubmed
The studies using an immunohistological technique revealed that overexpression of oxidative stress - related substance such as
HNE was observed in the liver of
primary biliary cirrhosis patients . -
pubmed
Four
patients in V - P group , 7 in
procaine group , and 19 in control group were shown to develop
ALI . -
pubmed
Two
patients were complicated with
acute renal failure in V - P group , 2 in
procaine group , and 5 in control group . -
pubmed
In a large , diverse cohort of
human immunodeficiency virus ( HIV )- infected persons receiving routine care , the proportion of eligible persons who discontinued primary prophylaxis against
Mycobacterium avium complex ( MAC )
infection , according to guidelines of the US Public Health Service and the
Infectious Diseases Society of America , increased from 16.7 % ( in 1996 ) to 84.9 % ( in 2002 ) . -
pubmed
Blood specimens were collected from all patients with suspect ' Alkhumra ' virus (
ALKV ) infection and tested for
ALKV ,
RVF ,
CCHF ,
dengue , and
West Nile encephalitis . -
pubmed
The disease seemed to be transmitted from
sheep or
goat to
humans by the mosquito
bites or direct contact with these animals . -
pubmed
Exercise intolerance is one of the most common symptoms in
patients with
mitochondrial myopathies (
MM ) . -
pubmed
Fewer
patients with
MM display overt
muscle atrophy and
weakness even in the absence of a
peripheral neuropathy . -
pubmed
METHODS : Twenty - two wide - necked , large or giant
aneurysms of the internal carotid artery ( ICA ) were treated in 22
patients with Onyx
HD 500 ( 15 ophthalmic , 1 clinoid , and 6
cavernous aneurysms ) . -
pubmed
Sixteen
patients were asymptomatic , and mass effect of the aneuryms caused
cranial nerve palsy in 6 . -
pubmed
Clinical follow - up demonstrated a
transient ischemic attack in 1
patient ; 2 with
cranial nerve palsy were unchanged , and 2 showed improved symptoms compared with the findings before treatment . -
pubmed
Patients with proven
peptic ulcer haemorrhage at endoscopy or operation were included in the study ; those with
bleeding under defined severe stress conditions were excluded . -
pubmed
We report a
patient with an initial diagnosis of
Lyme - associated pseudotumor cerebri who developed
cerebrospinal fluid pleocytosis consistent with
Lyme meningitis . -
pubmed
On the other hand , the
strain was less susceptible to
ischemic injury , and the number of surviving retinal neurons was significantly increased compared with that in wild - type
mice . -
pubmed
Secondary drowning in a
patient with
epilepsy . -
pubmed
In the current study , we assessed the sensitivity of the combined assay of these three markers in the detection of
human bladder transitional cell carcinoma . -
pubmed
METHODS : Voided urine samples of 100
patients with
bladder transitional cell carcinoma were obtained and each sample was aliquoted for the various assay . -
pubmed
HIV prevalence was 1.3 % , overall , 4.1 % in
FBDs and 0.1 % in non - FBDs in the community . -
pubmed
Amongst the subgroup of
FBDs ,
HIV prevalence was 1.5 % for whole blood only , 21.6 % for plasma only and 8.8 % for both . -
pubmed
BACKGROUND : Anger can precipitate
ventricular arrhythmias in
patients with implantable cardioverter - defibrillators ( ICDs ) . -
pubmed
METHODS : At the time of
shock ,
patients with ICDs recorded levels of defined mood states preceding the
shock in a diary . -
pubmed
The EGMs from 56 appropriate
shocks in 24
patients ( 18 male , mean age 66 years , 74 % with
coronary artery disease ) were reviewed and analyzed for morphology , mechanism of initiation ( sudden onset vs.
premature ventricular contraction [
PVC ] ) , pause dependence , and other characteristics . -
pubmed
Infection did not affect the distribution of overwintering larvae in a
white spruce canopy . -
pubmed
PURPOSE : To report 8
patients with misdiagnosis of MemoryLens intraocular lens ( IOL ) late postoperative
calcification and the resulting potentially avoidable procedures leading to secondary complications . -
pubmed
Half of the
patients were initially diagnosed as having
posterior capsular opacification and underwent
neodymium :
yttrium - aluminum - garnet laser capsulotomy . -
pubmed
Six of the 8
patients underwent subsequent lens exchanges , with 3 of them having postexchange complications including
endophthalmitis ,
cystoid macular edema , and
retinal detachment . -
pubmed
Because the drug is among the most frequently prescribed agents in the US , more controlled studies are required to determine the prevalence of
kidney stone disease among TPM users , and the optimal approach to prevent and treat
nephrolithiasis in these
individuals . -
pubmed
Trace elements in cerebrospinal fluid and blood from
patients with a rare progressive
central and peripheral demyelinating disease . -
pubmed
This prospective study was conducted on 52
HIV - positive patients with suspected
tuberculosis who were referred to our tertiary care hospital in New Delhi . -
pubmed
Twenty - seven
HIV - negative but suspected
tuberculosis patients were also included for comparison . -
pubmed
Of the 16 isolates from blood , 13 were diagnosed as
Mycobacterium tuberculosis and one each were identified as
M. - pubmed
kansasii , and a mixed
infection of M. tuberculosis and
M. - pubmed
181
participants were included in this analysis , 72 ( 40 % ) had moderate to severe
DD . -
pubmed
Cross - sectional studies of
men undergoing long - term ( & gt ; or = 12 months ) ADT reveal higher prevalence of
diabetes and
metabolic syndrome compared with controls . -
pubmed
Enteropathogenic
Escherichia Coli (
EPEC ) in Infants ' and Travelers '
Diarrhea . -
pubmed
Neutralisation of the in vitro
neurotoxic effects of
taipan venom was determined using a chick biventer cervicis nerve - muscle preparation . -
pubmed
All expired
taipan / polyvalent antivenom prevented in vitro
neurotoxicity at concentrations consistent with antivenom treatment . -
pubmed
A mutant of the
murine leukemia retrovirus MoMuLV - TB , called ts1 , causes this
syndrome in susceptible
strains of
mice . -
pubmed
The Arctic Sun Temperature Management System was used for heating and the
patient was warmed to 36.5 degrees C over 6 h. She was extubated after 48 h and transferred to a
psychiatric ward two days later . -
pubmed
Inhomogeneous
sodium accumulation in the ischemic core in
rat focal
cerebral ischemia by
23Na MRI . -
pubmed
BACKGROUND AND OBJECTIVES : By studying cardiometabolic risk factors in
children born after maternal biliopancreatic diversion bariatric surgery ( AMS ) compared with those in children born before maternal surgery ( BMS ) , we tested the hypothesis that significant maternal
weight loss may modify
obesity - related factors transmitted via the intrauterine environment . -
pubmed
DESIGN : Anthropometry and fasting blood levels were studied in 49
mothers who had lost 36 + /- 1.8 %
body weight sustained for 12 + /- 0.8 yr and their 111
children ( 54 BMS and 57 AMS ) aged 2.5 - 26 yr . -
pubmed
RESULTS : AMS
children had lower
birth weight ( 2.9 + /- 0.1 AMS vs. 3.3 + /- 0.1 kg BMS , P = 0.003 ) associated with a reduced prevalence of
macrosomia ( 1.8 AMS vs. 14.8 % BMS , P = 0.03 ) with no difference in
underweight . -
pubmed
Also
cyclosporine can achieve good results while sparing
steroids , particularly in
patients with persistently elevated
proteinuria . -
pubmed
These newer strategies may result in fewer adverse effects , better quality of life and better survival for
patients with proliferative
lupus nephritis . -
pubmed
Twenty and one
patients developed
AF . -
pubmed
Patients who developed
AF were older but their left ventricular ejection fraction was not different with
patients without
AF . -
pubmed
The ICU stay was higher in
patients with
AF . -
pubmed
Evaluation of the antihypertensive effect of
L - arginine supplementation in
patients with mild
hypertension assessed with ambulatory blood pressure monitoring . -
pubmed
The aim of this study was to evaluate the anti -
hypertensive efficacy and safety profile of
L - arginine during four weeks of oral supplementation to healthy subjects and
patients diagnosed with primary mild
hypertension . -
pubmed
Ambulatory blood pressure monitoring ( ABPM ) was used to allot
patients to either a healthy control group ( 19
subjects ) or the
hypertensive treatment group ( 35
patients ) . -
pubmed
RESULTS : Blood pressure ( both systolic and diastolic ) by ABPM showed statistically significant lowering after 4 weeks of
L - arginine supplementation only in the subgroup of
patients treated with 12 g of
L - arginine daily , with a stronger
hypotensive effect observed during the day . -
pubmed
METHODS : In this double - blind randomized study , 24 healthy
subjects were assigned to receive either an
influenza vaccine ( n = 15 ) as a model to generate a systemic inflammatory response or a sham vaccine ( n = 9 ) . -
pubmed
The most common symptom was
dysphagia , severe in 50
patients ( 40.6 % ) and moderate in 73 ( 59.4 % ) , with a mean
dysphagia score of 2.3 ( range 0 - 4 ) . -
pubmed
RESULTS : Good results were obtained in 82
patients ( 66.7 % ) , and the improvement of symptoms in 24 ( 19.5 % ) , data confirmed by pre versus postoperative
dysphagia mean score ( 2.3 vs 0.4 ) and by regurgitation score ( 0.8 vs 0.2 ) . -
pubmed
CONCLUSION : Nowadays esophago - diverticulostomy according to Collard , based on our results and on the literature data , represent the most effective and safe technique for the
patients with
Zenker ' s diverticulum , with low rate of morbidity and mortality compared to the others surgical on endoscopic procedures . -
pubmed
Wide gap arthroplasty if followed by vigorous physiotherapy may be sufficient in treating
TMJ ankylosis and prevent
recurrence in
adults . -
pubmed
Elevated cortical
glutamate in young
people at increased familial risk of
depression . -
pubmed
The authors made an analysis of the results of treatment of 924
patients with
non - small cell lung cancer , operated in the volume of pneumonectomy during 1990 - 2007 years and developed a method of complete suturing the mediastinum
wound in order to isolate the bronchus stump from the free pleural cavity and prevention of the development of a
bronchopleural fistula . -
pubmed
Effects of hyperbaric oxygenation on oxidative stress in acute transient focal cerebral
ischemic rats . -
pubmed
Rats were assigned to control or
HBO group after
brain ischemia . -
pubmed
In order to examine the role of
glutathione after
HBO treatment , another group of brain
ischemic rats were included to receive the
glutathione synthesis inhibitor and
HBO treatment . -
pubmed
The growing amount of literature about G - quadruplex DNA clearly demonstrates that such a structure is no longer viewed as just a biophysical strangeness but it is instead being considered as an important target for the treatment of various
human disorders such as
cancers or
venous thrombosis . -
pubmed
Mechanisms of
esophago - pharyngeal acid regurgitation in
human subjects . -
pubmed
Feasibility of sentinel lymph node biopsy in
breast cancer patients with initial axillary lymph node
metastasis after primary systemic therapy . -
pubmed
This strategy , however , does not eliminate unnecessary ALND in
patients with complete remission of axillary
metastases . -
pubmed
In
patients with successful lymphatic mapping , 70.7 % of
patients had residual axillary
metastases . -
pubmed
METHODS : The Covered Versus Balloon Expandable Stent Trial ( COBEST ) , a prospective , multicenter , randomized controlled trial , was performed involving 168 iliac arteries in 125
patients with severe
aortoiliac occlusive disease who were randomly assigned to receive a covered balloon - expandable stent or bare - metal stent . -
pubmed
Patient demographic data , clinical
signs and symptoms , TransAtlantic Inter - Society Consensus ( TASC ) classification , and preprocedure and postprocedure ankle - brachial index measurements were recorded . -
pubmed
, impairment affecting the ability to perform everyday activities ) associated with its therapy in pediatric
epilepsy , we retrospectively reviewed medical records of 156
patients receiving
vigabatrin at Cincinnati Children 's Medical Center from 1998 - 2010 . -
pubmed
To evaluate
visual impairment ( n = 63 ) , we reviewed serial ophthalmologic evaluations at baseline and during treatment for
patients in whom they were clinically indicated . -
pubmed
BACKGROUND AND OBJECTIVES : Previous studies have demonstrated that some
individuals suffering from
obsessive - compulsive disorder (
OCD ) are
impaired in verbal memory performance . -
pubmed
METHODS : Verbal memory performance of 36
participants with
OCD , 36
individuals with
major depression disorder (
MDD ) and 36 healthy controls was assessed with the California Verbal Learning Test under three different experimental conditions : ( 1 ) single - task condition , ( 2 ) while simultaneously focusing on their thoughts ( CSC condition ) , ( 3 ) while simultaneously focusing on external stimuli ( dual - task condition ) . -
pubmed
Three weeks postoperatively , the
patient presented with
limbal ischemia , recipient bed melt , and
wound dehiscence corresponding to the area of
bevacizumab injection . -
pubmed
CONCLUSIONS :
Multiple sclerosis should be considered in the differential diagnosis of
patients who present with
isolated cranial nerve palsies . -
pubmed
( 18 ) F - FDG is sensitive but has the limitation of giving false positive results in
patients with bone prosthesis , even if there is no
infection or mobilisation . -
pubmed
Sonographic appearance of synovial crystal deposits in 2
patients with
gout . -
pubmed
METHODS : Six cases of isolated median
neuropathy as the first sign of
leprosy were selected from
patients with an exclusively neurological complaint as the initial symptom . -
pubmed
The
patients , evaluated at the National
Leprosy Reference Center in Rio de Janeiro , Brazil , followed routine and specialized procedures . -
pubmed
RESULTS : Three of the
patients had pure
neural leprosy , and 3 had
skin lesions . -
pubmed
CONCLUSION : In addition to reconstructive surgery , psychiatric evaluation and intervention would be of benefit in the management of
cleft lip patients . -
pubmed
Main categories of findings include : nutrition - related effects ( including general
malnutrition and mortality ,
micronutrient malnutrition , and anti - nutrient consumption ) ; water - related disease ( including
E coli ,
cholera and algal bloom ) ; airborne and dust - related disease ( including silo gas exposure and
coccidioidomycosis ) ;
vector borne disease ( including
malaria ,
dengue and
West Nile Virus ) ; mental health effects ( including distress and other emotional consequences ) ; and other health effects ( including wildfire , effects of migration , and damage to infrastructure ) . -
pubmed
We established a
rat model of hepatic
fibrosis . -
pubmed
A 37 - year - old
man with a recurrent large scrotal mass after two surgeries , suffering with small urinary symptoms as a
dysuria and
nocturia , was examined before the third surgery on an outpatient basis . -
pubmed
The
patient 's serum
creatinine markedly improved , also
hernia and
ureterohydronephrosis was repaired with normally moisten without residual urine ( Fig . -
pubmed
CONCLUSIONS : Skip N2
metastasis is common in
patients with c - stage IA
NSCLC with high serum SLX , and lobectomy with complete dissection of hilar and mediastinal lymph nodes should remain the standard surgical procedure for these cases . -
pubmed
Reducing
lung cancer and other
tobacco - related
cancers in Europe : smoking cessation is the key . -
pubmed
METHOD : Ninety - three
patients with
migraine and
depressive symptoms - being evaluated for a larger project examining the impact of a behavioral intervention on
depression in
patients with
migraine - completed measures of
depression , disability ,
pain acceptance , and values - based action . -
pubmed
RESULTS : Twenty - five
patients with twenty - six
fractures were available for follow - up with a minimum required follow - up of twelve months . -
pubmed
Vitamin D concentrations and disease activity in Moroccan
children with
juvenile idiopathic arthritis . -
pubmed
The aim of this study was to assess the relationship between
hypovitaminosis D and disease activity in Moroccan
children with
juvenile idiopathic arthritis (
JIA ) . -
pubmed
METHODS : In this cross - sectional study , forty
children with
JIA were included , all having been diagnosed according to the classification criteria of International League of Associations for Rheumatology ( ILAR ) . -
pubmed
The supplement was 90 % DM and contained ( as - fed basis ) 47 %
corn gluten feed , 47 %
soybean hulls , 2 % feed grade limestone , and 4 % molasses . -
pubmed
Duration - dependence of the effect of treadmill exercise on
hyperactivity in
attention deficit hyperactivity disorder rats . -
pubmed
Spontaneously
hypertensive rats were used for the
ADHD rats and Wistar - Kyoto
rats were used for the control
rats . -
pubmed
The present study suggests that treadmill exercise for 30 min once a day is the most effective therapeutic intervention for
ADHD patients . -
pubmed
Preoperative predictors of ambulation ability at different time points after total hip arthroplasty in
patients with
osteoarthritis . -
pubmed
Forty - eight
women with unilateral THA were measured for hip extensor , hip abductor , and knee extensor muscle strength in both legs ;
hip pain ( visual analog scale , VAS ) ; and the Timed Up and Go ( TUG ) test pre- and postoperatively . -
pubmed
Rates of single
infections were 186/341 ( 54.5 % ) , 93/341 ( 27.3 % ) , and
3 / 341 ( 0.9 % ) , for
PRSV ,
PLDMV , and
PapMV , respectively ; 59/341 ( 17.3 % ) of the samples were co - infected with
PRSV and
PLDMV , which is the first time being reported in Hainan Island . -
pubmed
Intensive training of motor function and functional skills among young
children with
cerebral palsy : a systematic review and meta - analysis . -
pubmed
Therefore , the objective of this systematic review was to describe and categorise intensive motor function and functional skills training among young
children with
CP , to summarise the effects of these interventions , and to examine characteristics that may contribute to explain the variations in these effects . -
pubmed
Multi - antigen print immunoassay ( MAPIA)-based evaluation of novel recombinant
Leishmania infantum antigens for the serodiagnosis of canine
visceral leishmaniasis . -
pubmed
BACKGROUND : Domestic
dogs are the principal reservoir hosts of
Leishmania infantum in regions where
visceral leishmaniasis (
VL ) is endemic . -
pubmed
Our findings showed that the
canine immune response to antigen differs between
dogs and depends on
infection status . -
pubmed
Sigmoid
colon diverticulum perforated by a
chicken bone . -
pubmed
The present study was aimed at isolating R - phycocyanin ( RPC ) from
Porphyra haitanensis and determining the anti -
allergy potential of RPC in antigen - sensitized
mice and mast cells . -
pubmed
The most abundant species identified were
HAdV - F ( average 89.6 % ) and -A ( average 19.6 % ) , which are associated with
intestine infections . -
pubmed
Chronic stress promotes
oral cancer growth and angiogenesis with increased circulating
catecholamine and glucocorticoid levels in a
mouse model . -
pubmed
MATERIALS AND METHODS : We implanted
human oral cancer cell line
CAL 27 in
nude mice to investigate the effects of chronic stress on
tumor growth , and designed a physical restraint system to create an experimentally stressed
animal model , in which periodic immobilization induced characteristic chronic stress . -
pubmed
Tumor burdened
animal were randomly assigned into four groups : ( a ) control group , ( b ) daily stress for 2h with light , ( c ) daily stress for 2h in dark , and ( d ) daily stress for 6h with light . -
pubmed
We have successfully set up an
animal model , which studied the effect of chronic stress on
oral carcinoma growth rate and progression . -
pubmed
Damage severity on
soybean seeds was significantly reduced , compared with the untreated control , by both bacterial
strains ; however , the individual application of
phosphite showed to be least effective in controlling
M. - pubmed
Persistent
infection with high - risk
human papillomaviruses ( HR -
HPVs ) is the most important risk factor . -
pubmed
,
yeast grown on
galactose versus
glucose , or normal versus
cancer cells ) . -
pubmed
A 46 - year - old
woman on hemodialysis due to
end - stage renal disease was admitted for repeated
thrombus formation in previously implanted drug - eluting stents in the right coronary artery . -
pubmed
Bilateral occipital extradural hematoma in a
child . -
pubmed
Extradural hematoma (
EDH ) occurs in approximately 2 % of all
patients with
head injuries . -
pubmed
Bilateral
EDHs account for 2 - 10 % of all acute
EDHs in
adults but are exceedingly rare in
children . -
pubmed
EDHs in
children are more frequently venous ( from tears of a dural
sinus or diploic veins ) and consequently have a better prognosis than
EDHs in adults . -
pubmed
We are reporting such rare form of
injury as
bilateral occipital EDH with supratentorial extension in 12 years
child following road traffic accident . -
pubmed
Human parvovirus B19 ( B19V ) infection causes a number of diseases in
humans , and , in some circumstances , can be life threatening . -
pubmed
These groups included
anemia patients ,
Mycoplasma pneumonia- and
Treponema pallidum - infected patients ,
HIV - positive individuals , and healthy blood donor volunteers . -
pubmed
The analogue
4 - NH2BS - THQ demonstrated a broader spectrum of activity than
BS - THQ , with a minimum inhibitory concentration of 100 microg / mL against reference
strains of
S. - pubmed
BACKGROUND :
Rabies is a global problem which occurs in more than 150 countries and territories including Sri Lanka , where
human deaths from
rabies are in decline whilst resources incurred for prevention of
rabies are in sharp incline over the years . -
pubmed
To characterize
sugar glider RVA in detail , one
strain ,
RVA / SugarGlider - tc / JPN / SG385 / 2012 / G27P[36 ] ( SG385 - tc ) , was isolated . -
pubmed
of
strain SG385 - tc had
diarrhoea and the 50 %
diarrhoea - inducing dose ( DD50 ) of
strain SG385 - tc in suckling
mice was 1.2 x 104 f.f.u . -
pubmed
Prevalence of
gastrointestinal helminths and management practices for
dogs in the Greater Accra region of Ghana . -
pubmed
Toxocariosis and
ancylostomosis remain the most important
parasitic infections affecting companion animals worldwide and pose a risk to animal and
human health . -
pubmed
Management practices for control of
helminths in dogs were assessed through questionnaire interviews of the
dog owners . -
pubmed
Hookworm eggs were found in 178 ( 46.8 % ) dogs ,
Toxocara canis eggs in 22 ( 5.8 % ) and
mixed infections of hookworms and
T. - pubmed
Younger women will use botanicals for
urinary tract infections , especially
Vaccinium macrocarpon (
cranberry ) , where there is evidence for efficacy . -
pubmed
Some examples include
Vitex agnus -
castus (
chasteberry ) ,
Angelica sinensis ( dong quai ) ,
Viburnum opulus / prunifolium (
cramp bark and
black haw ) , and
Zingiber officinale (
ginger ) . -
pubmed
Pregnant women have also used
ginger for relief from
nausea . -
pubmed
Dentin hypersensitivity - like
tooth pain seen in
patients receiving
steroid therapy : An exploratory study . -
pubmed
To ascertain whether
steroid therapy evokes
dentin hypersensitivity (
DH)-like
tooth pain , we performed a study based on compelling evidence from
patients receiving
steroid therapy . -
pubmed
The prevalence of SD
tooth pain was 17.7 % ( 39/220
patients ) . -
pubmed
SD
tooth pain was significantly more frequent in pulse therapy
patients than in non -
pulse therapy
patients ( p & lt ; 0.05 ) . -
pubmed
It is even rarer in
patients with no previous known risk factors for either
tumour . -
pubmed
Here , we present a case of synchronous non - functioning
pituitary adenoma with
suprasellar and olfactory groove meningiomas in a
patient without previous irradiation . -
pubmed
METHODS : The
tumours were diagnosed on MRI in the 65 - year - old
patient who presented with patchy
visual deficits . -
pubmed
Early detection of
West Nile virus in France : quantitative assessment of syndromic surveillance system using nervous signs in
horses . -
pubmed
In our study , we assessed whether or not data collected by the passive French surveillance system for the surveillance of
equine diseases can be used routinely for the detection of
WNV . -
pubmed
High - frequency repetitive transcranial magnetic stimulation for treating moderate
traumatic brain injury in
rats : A pilot study . -
pubmed
Moderate
TBI was induced in adult male
Sprague Dawley rats using Feeney 's weight - dropping method . -
pubmed
We present a case report of recurrent
gastric cancer with
bone marrow metastasis in a
patient with no evidence of
systemic disease on follow - up for two years post surgical resection . -
pubmed
METHODS : We reviewed the medical records of a
patient who presented with metastatic
gastric adenocarcinoma to the bone marrow two years post R0 subtotal gastrectomy with Roux - en - Y gastrojejunostomy without evidence of
systemic disease on follow up for two years . -
pubmed
The data and
strains described here will provide a valuable guide and resource for future functional exploration of
C. - pubmed
Short - term treatment with
eicosapentaenoic acid improves
inflammation and affects colonic differentiation markers and microbiota in
patients with
ulcerative colitis . -
pubmed
In this pilot study we evaluated the effect of
Eicosapentaenoic acid as free
fatty acid (
EPA - FFA ) supplementation on mucosal disease activity , colonic differentiation markers and microbiota composition in
UC patients . -
pubmed
In conclusion ,
EPA - FFA supplementation reduced mucosal
inflammation , promoted goblet cells differentiation and modulated intestinal microbiota composition in long - standing
UC patients . -
pubmed
Non - traumatic
OHCA patients transferred to the hospital from April 2013 through August 2016 were analyzed . -
pubmed
Proangiogenic effects of
tumor cells on endothelial progenitor cells vary with
tumor type in an in vitro and in vivo
rat model . -
pubmed
The present study aimed at investigating the influence of 4 different
tumor types on angiogenic properties of EPCs in an in vitro and in vivo
rat model . -
pubmed
Coinjection of encapsulated
tumor cells , especially
mammary carcinoma cells , and EPCs in a
rat model confirmed a contributing effect of EPCs in
tumor vascularization . -
pubmed
The present study will contribute to a better understanding of
tumor - induced vascularization , thus facilitating the development of therapeutic strategies targeting
tumor - EPC interactions.-An , R. , Schmid , R. , Klausing , A. , Robering , J. W. , Weber , M. , Bauerle , T. , Detsch , R. , Boccaccini , A. R. , Horch , R. E. , Boos , A. M. , Weigand , A. Proangiogenic effects of
tumor cells on endothelial progenitor cells vary with
tumor type in an in vitro and in vivo
rat model . -
pubmed
Objective : To investigate the clinical value of Bayesian network in predicting survival of
patients with advanced
gallbladder cancer(
GBC)who underwent curative intent surgery . -
pubmed
NMLN , margin , T staging and pathological grade are the top 4 risk factors affecting the survival of
patients with advanced
GBC who underwent curative resection . -
pubmed
Streptococcus pneumoniae is the major bacterial cause of community - acquired
pneumonia , and the leading agent of childhood
pneumonia deaths worldwide . -
pubmed
Neutrophil uptake and killing of the serotype 3
strain was significantly impaired compared to the serotype 4
strain and depletion of neutrophils with antibody enhanced survival of
mice infected with the highly encapsulated SRL1
strain . -
pubmed
Age - related changes in the tactile pressure sensitivity threshold in the sole of the foot in
diabetic patients . -
pubmed
[ Purpose ]
Patients diagnosed with
diabetes mellitus (
DM ) are known to experience sensory disturbances in their feet secondary to
diabetic neuropathy (
DN ) . -
pubmed
The sole of the foot tactile pressure sensitivity threshold in
patients with
DM was evaluated in addition to examining age - related effects based on the sites studied . -
pubmed
Whether the tactile pressure sensitivity threshold in the sole of the foot in elderly
patients with
DM was associated with the duration of
DM or aging was evaluated . -
pubmed
[ Participants and Methods ] Our study included 204
patients with
DM ( 136males and 68 females ) . -
pubmed
Reductions in
lung metastases were demonstrated for two analogs in a late - stage experimental
mouse metastasis model , and one analog completely inhibited formation of
liver metastases in an orthotopic xenograft
mouse model of
pancreatic cancer . -
pubmed
CASE PRESENTATION : We present a rare case of a 49 - year - old Egyptian
man who presented to our emergency department complaining of
cough and vague
abdominal discomfort who was found to have
Chilaiditi syndrome diagnosed radiologically by computed tomography scan . -
pubmed
We aimed to investigate the prognostic value of serum cell
death markers in
patients with
hepatitis B virus (
HBV)-related acute decompensation (
AD ) of
cirrhosis with and without
acute - on - chronic liver failure (
ACLF ) . -
pubmed
We studied two cohorts - cohort 1 : 201
outpatients with stable
chronic hepatitis B ( 49
cirrhosis ) ; cohort 2 : 232 inpatients with
HBV - related
cirrhosis admitted for
AD . -
pubmed
The study included 51
patients with
RA . -
pubmed
ACD was found in 37.3 % of
patients ,
IDA in 11.8 % , and combined (
ACD /
IDA ) in 17.6 % . -
pubmed
IDA alone or combined with
ACD was encountered in about a third of
patients . -
pubmed
The acute psychological pressure score and the psychological pressure self - test score in the experimental group were both lower than that in the control group ( P & lt ; .05).Comprehensive nursing intervention for otolaryngology
patients was associated to relieving
pain after the operation and psychological pressure of patients in the short and long term . -
pubmed
infection in
sheep population of Ladakh , India . -
pubmed
Ladakh is the high altitude ( 11,184 ft above sea level ) cold desert region in the state of Jammu & amp ; Kashmir ( India ) , where winter temperature goes below - 35 C. A total of 37 faecal samples were collected from local Changthangi and Russian merino
sheep of the Leh region of Ladakh , having the history of
diarrhoea and
emaciation , followed by
death . -
pubmed
infection in adult
sheep from India . -
pubmed
Sensitivity and specificity of meningeal signs in
patients with
meningitis . -
pubmed
In this study , we examined the involvement of cell
death signaling in tissue - size determination using
Drosophila wing as a model . -
pubmed
INTRODUCTION :
Mantle cell lymphoma (
MCL ) is a subtype of
B - cell non - Hodgkin lymphoma (
NHL ) , and the purpose of this study was to evaluate the prognostic value of
25 - hydroxy vitamin D [
25 -( OH ) D ] deficiency among
patients with
MCL . -
pubmed
MATERIALS AND METHODS : Seventy
MCL patients with serum
25 -( OH ) D were enrolled in this study . -
pubmed
The effects of
ginger supplementation on inflammatory , antioxidant , and periodontal parameters in
type 2 diabetes mellitus patients with
chronic periodontitis under non - surgical periodontal therapy . -
pubmed
Background : The aim of this study was to evaluate the effects of
ginger supplementation on inflammatory , antioxidant , and periodontal parameters in
type 2 diabetes mellitus (
T2DM )
patients with
chronic periodontitis (
CP ) under non - surgical periodontal therapy ( NSPT ) . -
pubmed
Material and methods : In this double - blind clinical trial study , 46
T2DM patients with
CP were randomly allocated to intervention and control groups and received either 4 tablets 500 mg ( 2 g )
ginger or placebo twice a day for 8 weeks . -
pubmed
Conclusion : It is recommended that
ginger supplementation along with NSPT may be effective in the improvement of
inflammation , oxidative , and periodontal status in
T2DM with
CP . -
pubmed
Results : Thirteen studies involving 1172
cancer patients and 32 TCGA
cancer types involving 9676
cancer patients were eventually selected . -
pubmed
The initial FDA instructions for use ( IFU ) limited its use to
patients 22 years old or older with wide - necked large or giant
aneurysms of the internal carotid artery ( ICA ) from the petrous segment to superior hypophyseal artery / ophthalmic segment . -
pubmed
BACKGROUND : Ordinary meta - analyses indicate that
magnesium sulphate (
MgSO4 ) treatment to
women at imminent risk for preterm delivery decreases the offspring 's risk of
cerebral palsy (
CP ) . -
pubmed
Increasing psychophysical evidence suggests that specific image features - or statistics - can appear unpleasant or induce
visual discomfort in
humans . -
pubmed
Administration of secretome from
human placental stem cell conditioned media improves recovery of erectile function in the
pelvic neurovascular injury model . -
pubmed
CONCLUSION : Injection of the secretome isolated from
human PSC improves erectile functional recovery and histological structure in a
rat model of
neurovascular injury - induced
ED . -
pubmed
MATERIALS AND METHODS : The subjects were 701 consecutive
patients ( mean age 74 + -9 years ; 492
men ) with 817 de novo
SFA lesions treated with BNS implantation between January 2004 and September 2015 . -
pubmed
Uncariae Ramulus Cum Uncis ( UR ) has a long - term history for the treatment of
cardiovascular and central nervous systems disorders in China and Eastern Asia . -
pubmed
BACKGROUND : In the field of
melanoma , clinical trials evaluating the impact of sentinel node biopsy , completion lymph node dissection and adjuvant medical therapies on
patient outcomes have provided evidence that has changed practice significantly over the past five years . -
pubmed
OBJECTIVES :
Coronavirus disease 2019 ( COVID-19 ) , caused by the novel
severe acute respiratory syndrome coronavirus 2 (
SARS - CoV-2 ) , has become a global pandemic , raising widespread public health concerns . -
pubmed
Response to : ' Antirheumatic drugs , B cell depletion and critical COVID-19 : correspondence on ' Clinical course of
coronavirus disease 2019 ( COVID-19 ) in a series of 17
patients with
systemic lupus erythematosus under long - term treatment with
hydroxychloroquine by Mathian et al ' by Notz et al . -
pubmed
INTRODUCTION :
Vancomycin remains first - line therapy for
methicillin - resistant
Staphylococcus aureus (
MRSA )
blood stream infections (
BSI ) ; however , its toxicity and reported clinical failures are well established . -
pubmed
aureus
BSI was adjusted and applied to this cohort to compare
vancomycin - treated versus
daptomycin /
ceftaroline - treated
patients . -
pubmed
During the mean follow - up ( FUP ) of 275 + - 88 days ,
patients in the PCI group reported less physical activity limitations ( 72.7 + - 21.3 versus 60.5 + - 27 , P = 0.014 ) , less frequent
angina episodes ( 89.8 + - 17.6 versus 76.8 + - 27.1 , P = 0.006 ) , better QoL ( 79.9 + - 22.7 versus 62.5 + - 25.5 , P = 0.001 ) , greater treatment satisfaction ( 91.2 + - 13.6 versus 81.4 + - 18.4 , P = 0.003 ) , and borderline differences in
angina stability ( 61.2 + - 26.5 versus 51.0 + - 23.7 , P = 0.046 ) compared to patients in the OMT group . -
pubmed
METHODS :
Patients thought - on the basis of having a firm , immobile mass centered on the lacrimal sac fossa - to possibly have
lacrimal sac malignancy were identified from a database of biopsies between 1989 and 2020 . -
pubmed
One - fifth of malignant lesions had
pain , whereas all the benign conditions were painless , and acute
dacryocystitis was relatively uncommon - occurring in only 13 % of
patients . -
pubmed
A Pilot Study of Switching Electroconvulsive Therapy for
Patients With Treatment Resistant
Schizophrenia or
Mood Disorder . -
pubmed
Neonatal GAT tolerance could be transferred in adult and involved suppressor T cells in the two inbred
strains , whereas the GT - specific immune suppression was not demonstrable in newborn BALB / c
mice . -
pubmed
Chronic haemolytic anaemia in two
patients heterozygous for
erythrocyte pyruvate kinase deficiency . -
pubmed
Two
patients with mild
chronic haemolytic anaemia , a mother and her son , were found to be heterozygous for
erythrocyte pyruvate kinase deficiency . -
pubmed
The relationship between neurovirulence and induction of
hydrocephalus was investigated for a
measles virus temperature - sensitive mutant and its revertant . -
pubmed
The evidence derives mainly from experiments on
Schistosoma mansoni infections in the
mouse with their immune status variously modulated ; this review emphasises
praziquantel (
PZQ ) , which is now the main drug used for treatment of
human schistosomiasis . -
pubmed
The potential relevance of these observations for enhancing the efficacy of drugs currently used to treat
human schistosomiasis , and for devising novel therapeutic strategies , is discussed . -
pubmed
In this updated and expanded retrospective analysis , the treatment records of 24
patients with
brain metastases from
nonseminomatous germ cell testicular tumors ( NSGCT 's ) treated at the Indiana University Department of Radiation Oncology from 1975 through 1988 were reviewed . -
pubmed
Group 1 ( n = 10 ) consisted of
patients who presented initially with
brain metastases and had no prior systemic treatment . -
pubmed
Group 3 ( n = 10 ) consisted of those
patients who were initially treated with
PVB + /-
doxorubicin or
bleomycin ,
etoposide , and
cisplatin (
BEP ) and eventually developed progressive disease and
brain metastases . -
pubmed
Patients with brain
metastases who have potentially controllable systemic disease should be treated curatively with WBRT ( 5000 cGy/25 fractions ) + /- surgical excision and concomitant chemotherapy . -
pubmed
Forty - three
patients with recurrent and metastatic
squamous cell carcinoma of the cervix received a program of sequential combination chemotherapy incorporating induction with
cisplatin ,
vinblastine , and
bleomycin (
PVB ) and subsequent consolidation with
5 - fluorouracil ,
doxorubicin ,
cyclophosphamide , and
vincristine (
FACV ) . -
pubmed
However , the only cumulative
toxicity was
peripheral neuropathy , although this was only moderate to severe in 2
patients . -
pubmed
The influence of Mesocestoides corti on subsequent
Angiostrongylus cantonensis infections in
mice . -
pubmed
The influence of Mesocestoides corti on subsequent
Angiostrongylus cantonensis infection in
mice ( C57BL/6 and BALB / c ) was assessed . -
pubmed
Both
strains of
mice infected with
M. - pubmed
corti were given A. cantonensis
infection 18 days later , but pre - existing
M. - pubmed
BALB / c
mice with mixed
parasite infections showed low morbidity and mortality as compared with
mice singly infected with A. cantonensis and some
mice demonstrated a pulmonary migration of intracranial worms . -
pubmed
C57BL/6
mice with mixed
parasite infections failed to resist A. cantonensis reinfection . -
pubmed
corti biomass was significantly higher in
mice with mixed
parasite infections than mice with monoinfection with
M. - pubmed
These data suggest a distinct difference in response to A. cantonensis
infection between C57BL/6 and BALB / c
mice , and the induction of immunosuppression in both
mouse strains following
M. - pubmed
Based on these data , the recommended
amikacin dosage in
chickens is 20 mg / kg
body weight every 8 h. -
pubmed
An illustrative
patient is presented in whom these vessels were used for a combined serratus anterior - latissimus dorsi free muscle flap for sacral
wound coverage . -
pubmed
Four
patients have died of their disease , and there was one treatment - related
death . -
pubmed
The anti - inflammatory effects of
D - myo - inositol-1.2.6 - trisphosphate (
PP56 ) on
animal models of
inflammation . -
pubmed
Systemic infection caused by
Penicillium decumbens in a patient with
acquired immunodeficiency syndrome . -
pubmed
The prognosis of both operated and non - operated
tumour patients , is determined exclusively by the
recurrence and progression of the
tumour disease . -
pubmed
Time course of change in
oxygen saturation and peak expiratory flow in
children admitted to hospital with acute
asthma . -
pubmed
Serial measurements of SaO2 were made in 47
children during an acute attack of
asthma that required admission to hospital . -
pubmed
These data suggest that in
children admitted to hospital for acute
asthma arterial
oxygen saturation is low at admission , recovers more slowly than airway function , reflects bronchodilatation with
salbutamol only when SaO2 is low , and recovers more rapidly in younger children than in older children . -
pubmed
A randomized , double - blind trial was performed to assess serological response and clinical protection for acute
gastroenteritis due to
rotavirus in 103
children aged 6 to 18 months , after a single dose of RIT 4237 live attenuated
bovine rotavirus vaccine or placebo . -
pubmed
One hundred sixty
patients intolerant of or
allergic to
sulfasalazine (
Salazopyrin ,
Azulfidine ) participated in an open tolerance study of
azodisal sodium (
Dipentum ) . -
pubmed
More than 4 of every 5
patients tolerated
azodisal sodium well , but 12.5 % of patients stopped medication because of
diarrhea . -
pubmed
Even after 7
patients who had also experienced
diarrhea when taking
sulfasalazine were excluded , there still remained a group of
patients ( 9.8 % ) who had to discontinue
azodisal sodium because of
diarrhea . -
pubmed
Of these , 23.1 % of the
patients treated with
azodisal sodium and 44.9 % of the
patients treated with placebo had a clinical and sigmoidoscopic
relapse during a 6 - mo trial period ( p = 0.02 ) . -
pubmed
Changes in ambulatory activity and
dopamine turnover in
streptozotocin - induced
diabetic rats . -
pubmed
We observed decreased ambulatory activity in
STZ - induced
diabetic rats during the dark , but not the light , cycle . -
pubmed
Moreover , ambulatory activity in
STZ - induced
diabetic rats gradually decreased , while the blood
glucose level rose . -
pubmed
The present study suggests that there are metabolic abnormalities in the striatum dopaminergic neurons of
STZ - induced
diabetic rats associated with decreased ambulatory activity . -
pubmed
In 72 % of 143
patients undergoing a second coronary bypass grafting , mural or occlusive late
thrombosis was observed histologically in 69 % of 173 resected grafts . -
pubmed
Alterations in appendicular skeletal mass in
patients with rheumatoid ,
psoriatic , and
osteoarthropathy . -
pubmed
Appendicular bone mass was measured in a series of 50
patients with non - steroid treated
rheumatoid arthritis , 20 with polyarticular seronegative
psoriatic arthritis , and 30 with
osteoarthrosis , and compared with that of 40 controls of similar age and sex . -
pubmed
Distal forearm bone mineral content was reduced in
patients with rheumatoid and
psoriatic arthritis and increased in those with
osteoarthrosis . -
pubmed
The increase in bone mass in
patients with
osteoarthrosis was confined to those with
isolated large joint disease and was not found in those with primary generalised
osteoarthrosis . -
pubmed
Because of the observed ability of
retinoids to reverse other dysplastic conditions in vitro and in vivo , a number of clinical studies have been carried out of the effect of these agents on
cervical dysplasia , with the object of developing a means of chemoprevention of
cervical malignancies in
women at risk . -
pubmed
The outcome of the latter investigation will have important implications , not only for the management of
patients with
cervical dysplasia but also for therapeutic approaches to other
precancerous conditions . -
pubmed
The authors retrospectively evaluated their radiographic experience with this
injury in 27
patients over a 24 - month period . -
pubmed
CT studies provided better delineation of the
fracture in all 21
patients and significant additional information in five
patients ( 24 % ) . -
pubmed
Seven
patients ( 26 % ) suffered initial neurologic sequelae in association with the
C-2 injury . -
pubmed
Nine
patients had additional sites of
fracture , including seven with associated C-1 ring disruption ( 26 % ) . -
pubmed
Extension of the
fracture line into the transverse vertebral artery foramen led to
vertebral artery injury and cerebellar embolization in one
patient . -
pubmed
OSA has been shown to have developed in two
patients with
HSS . -
pubmed
Reduction of
aspirin - induced
fecal blood loss with low - dose
misoprostol tablets in
man . -
pubmed
This indicates a potential role for
misoprostol in the prevention of
gastric mucosal damage in selected
patients . -
pubmed
Serum
18 - hydroxycorticosterone ,
aldosterone , and
potassium were measured under basal conditions in 34
patients with documented
primary aldosteronism , 10
patients with
essential hypertension , and 9 normal
subjects . -
pubmed
The results revealed that 22 of 23
patients with
aldosterone - producing
adenomas had
18 - hydroxycorticosterone levels greater than 100 ng / dl , and all 9
patients with
idiopathic adrenal hyperplasia had plasma levels less than 100 ng / dl . -
pubmed
Two
patients with unusual macromicronodular
hyperplasia of the adrenal glands had levels greater than 100 ng / dl . -
pubmed
We found a significant relationship between serum
potassium and the ratio of
18 - hydroxycorticosterone to
aldosterone in
patients with
idiopathic adrenal hyperplasia , but not in those with an
aldosterone - producing
adenoma . -
pubmed
Observations on commensal cultures of
Bordetella bronchiseptica and
rat hepatoma cells . -
pubmed
Identification of filamentous micro - organisms of the
human dental plaque by immuno - fluorescence . -
pubmed
[ The state of the blood coagulation system in
acute appendicitis patients ] . -
pubmed
Diuresis in newborn
rat given intravenous water or salt solution . -
pubmed
The effects of feeding saturated and eucaloric unsaturated fat - rich diets on
lipemia and
insulinemia in female
Brown Norway rats have been compared . -
pubmed
[ Programmed electric stimulation in a pregnant
woman with
mitral valve defect and
ventricular arrhythmia with
bradycardia ] . -
pubmed
In order to search into the mechanism of the
potassium contracture of the
dog coronary artery the effects of
procaine were studied in the isolated smooth muscle preparation of the
dog coronary artery . -
pubmed
These findings suggest that the
potassium contracture of the
dog coronary artery is dependent on the
calcium - induced
calcium release mechanism . -
pubmed
The liability to encounter severe side effects is often enhanced in
patients with underlying
cardiovascular diseases , which may change the usual drug action either by inducing modifications of the drug pharmacolinetic or by altering the receptor sensitivity . -
pubmed
A few severe
chromosome aberrations , such as dicentrics or translocations , appeared in the control
animals as well as in the
lead - treated ones , during the course of the experiment . -
pubmed
In clinical trials in
patients with
rheumatic diseases or
pain arising from other conditions , it was as effective an analgesic as standard
piroxicam , and showed a faster onset of action on the first day of treatment . -
pubmed
In short term pharmacodynamic studies in healthy
volunteers ,
piroxicam - beta - cyclodextrin was equivalent to or tended to show less
gastrointestinal mucosal toxicity than standard
piroxicam , as assessed by endoscopy and
faecal blood loss . -
pubmed
Thus ,
piroxicam - beta - cyclodextrin is an effective agent in
patients with
rheumatic diseases or other
pain states . -
pubmed
In four
patients ( group 1 ) ,
coronary ischemia had developed 0.5 - 70 months ( mean , 31 months ) after IMA - to - coronary artery bypass surgery . -
pubmed
In four other
patients ( group 2 ) ,
atherosclerotic subclavian stenosis had developed proximal to a donor IMA before planned bypass surgery . -
pubmed
RESULTS : Group 1
patients were free of
myocardial ischemia at follow - up ( mean follow - up , 39.0 months ; range , 14 - 101 months ) . -
pubmed
We used artificial augmentation of
CO2 at a rate of 1 l / min after preoxygenation with 100 %
O2 to test for
apnea in 34
patients with suspected
brain death . -
pubmed
All CBA
mice that had been immunised by means of four successive inoculations of
Plasmodium berghei NK65 , each inoculation being followed by chemotherapy , survived an intravenous challenge inoculation of parasite , with 4/12
mice developing patent
parasitaemia that resolved within 2 weeks . -
pubmed
Effects of
cyclopentenone prostaglandins on myeloid cells during early
infection with
HTLV - I. -
pubmed
Human myeloid cell lines at different stages of differentiation (
K562 ,
HL60 and
U937 ) were used to analyze the permissivity of the myelomonocytic lineage to
acute infection with
human T - cell leukemia virus type - I ( HTLV - I ) after cell - to - cell transmission and to evaluate the effect of
cyclopentenone prostaglandins ( PG ) A1 and
PGJ2 on virus transmission , proliferation of recipient cells and cell - mediated
cytotoxicity against virus - donor cells . -
pubmed
A study of
obese cats on a calorie - controlled
weight reduction programme . -
pubmed
Twenty - two domestic
cats were fed a commercial low calorie diet for the management of
obesity for up to 18 weeks and showed an average
weight loss of 13.5 per cent of their body - weight . -
pubmed
There was no indication that a steady
weight loss over the study period had any adverse effect on the hepatic function or general health of the
cats . -
pubmed
Efficacy of
erythromycin compared with
penicillin /
streptomycin for the treatment of virulent
footrot in
sheep . -
pubmed
Antipsychotic agents , most often used for treatment of
schizophrenia , are sometimes prescribed for the agitated
patient with an
organic brain disorder . -
pubmed
We report the case of a
brain - injured patient who was prescribed
chlorpromazine for
agitation and who developed a delusional state while taking this antipsychotic agent . -
pubmed
Caution is advised when prescribing neuroleptics for
patients with
traumatic brain injury , especially those agents with significant cognitive side - effects or with a significant potential to precipitate
seizures . -
pubmed
Tissue and plasma concentrations of
pentose - derived glycation end - products ( "
pentosidine " ) are elevated in
diabetic patients with normal renal function and in both
diabetic and nondiabetic
patients with
end - stage renal disease . -
pubmed
We conclude that
renal failure is the major factor accounting for the accumulation of
pentosidine in both
diabetic and nondiabetic
patients with
end - stage renal disease . -
pubmed
Coronary artery bypass grafting in a
patient with multiple
intracranial aneurysms and recent
subarachnoid hemorrhage . -
pubmed
The present brief review deals specifically with data obtained with
urapidil in the treatment of elderly
hypertensive patients . -
pubmed
Some of these data , dealing with 245
patients aged & gt ; or = 65 years , have previously been published , but additional data from more than 5000
hypertensive patients in this age group on file will be reviewed as well . -
pubmed
Random amplified polymorphic DNA ( RAPD ) analysis was applied to genomic DNA from nineteen
yeast strains belonging to the genera Saccharomyces and Zygosaccharomyces . -
pubmed
Photoinduced
toxicity of
PAHs to the foliar regions of
Brassica napus (
canola ) and
Cucumbis sativus (
cucumber ) in simulated solar radiation . -
pubmed
napus (
canola ) and
Cucumbis sativus (
cucumber ) , were chosen to test the photoinduced
toxicity of six
PAHs (
anthracene ,
phenanthrene ,
benzo ( a ) anthracene ,
benzo ( a ) pyrene ,
flouranthene , and
pyrene ) . -
pubmed
SUBJECTS : 52
patients who underwent gastric resection for
gastric cancer that was invading the muscularis propria , and for whom clinical follow - up data were available . -
pubmed
Microdialysis probe delivery of an isotonic high - K+ solution to the
rat amygdala for 60 - 70 min produces
neuronal necrosis , edematous neuropil and increases in extracellular
glutamate and
aspartate . -
pubmed
Oxidative stress is postulated to be increased in
patients with
IDDM . -
pubmed
RESULTS :
HIV - positive men were more likely to develop
HSIL than
HIV - negative men relative risk ( RR ) , 3.7 ; 95 % confidence interval ( CI ) , 2.6 - 5.7 . -
pubmed
Reduced incidence of
septic arthritis in children by
Haemophilus influenzae type - b vaccination . -
pubmed
In many countries
Haemophilus influenzae type b (
Hib ) is the second most common cause of
septic arthritis in children . -
pubmed
Human arachnoid villi response to
subarachnoid hemorrhage : possible relationship to
chronic hydrocephalus . -
pubmed
A case is presented in which the revised diagnosis of
infrapatellar contracture syndrome was made after noting delayed progress in the rehabilitation of an active female
patient with a presumed
anterior horn medial meniscus tear and a contracted patellar tendon . -
pubmed
Group D
rats ' lateral skin
necrosis compared significantly less with group C ( p & lt ; 0.001 ) . -
pubmed
The signs among infected
cattle and
sheep were high
fever ,
icterus ,
bloody diarrhoea and
abortion . -
pubmed
The same suspensions caused
paralysis and mortalities two to three days post intracerebral injection in
mice . -
pubmed
Importation of infected ruminants , especially
camels from the Sudan , is the principal source of
infection . -
pubmed
The
patient - doctor relationship plays a crucial role in conservative treatment of
sciatic pain . -
pubmed
Eight
patients ( 9
fractures ) who have been treated with Dall - Miles plating in this unit between April 1996 and October 1997 for ipsilateral
periprosthetic fractures around total hip replacement ( 7 cases ) and total knee replacement ( 2 cases ) have been reviewed . -
pubmed
Subcutaneous
emphysema developed in three
patients with no sequelae . -
pubmed
An episode of acute
upper airway obstruction was caused by a lingual
haematoma , when a
patient with
end stage renal failure suffered a
hypocalcaemic fit and bit his tongue . -
pubmed
We have studied the recruitment and roles of distinct dendritic cell ( DC ) precursors from the circulation into
Propionibacterium acnes - induced
granulomas in
mouse liver . -
pubmed
Diffuse cortical reduction of neuronal activity in unipolar
major depression : a retrospective analysis of 337
patients and 321 controls . -
pubmed
All investigations were included comparing regional cerebral blood flow ( rCBF ) or
glucose metabolism ( rCMRGlc ) between acutely
depressed unipolar major
depressive patients and healthy controls . -
pubmed
In
patients with unipolar
major depression rCBF and rCMRGlc were lowered in left ( -4.4 % , P = 0.022 ) and right frontal ( -3.2 % , P = 0.053 ) , left ( -1.7 % , P = 0.061 ) and right temporal ( -3.0 % , P=0.003 ) , left ( -6.5 % , P = 0.002 ) , and right parietal ( -8.8 % , P=0.001 ) , and left ( -6.6 % , P = 0.083 ) and right occipital cortex ( -4.2 % , P = 0.02 ) . -
pubmed
Liver cirrhosis was induced by
CCl ( 4 ) inhalation and
phenobarbital in
Wistar rats . -
pubmed
Clinical impact of endoscopic ultrasound - guided fine needle aspiration biopsy in
patients with
upper gastrointestinal tract malignancies . -
pubmed
BACKGROUND AND STUDY AIMS : Several studies have evaluated the accuracy of endoscopic ultrasound - guided fine - needle aspiration biopsy ( EUS - FNAB ) in the upper gastrointestinal tract , but so far no studies have specifically evaluated the clinical impact of EUS - FNAB in
upper gastrointestinal tract cancer patients . -
pubmed
PATIENTS AND METHODS : Between 1997 and 1999 , 307 consecutive
patients were referred for EUS with a diagnosis or strong suspicion of
esophageal , gastric or pancreatic cancer ; 274
patients were potential candidates for surgical treatment and had EUS . -
pubmed
We examined 40
CD patients [ 31 not being treated with a gluten - free diet ( GFD ) and 9 being treated with a GFD ] and 30 non - CD
patients . -
pubmed
BACKGROUND : Acute
septic cholecystitis (
AC ) remains a difficult problem in
patients with coexisting severe illness , and ultrasonographically guided percutaneous puncture and drainage of the gallbladder ( PTBD ) may be an alternative treatment in this context . -
pubmed
Seven
patients had an intraperitoneal bile leak and 2 had worsening
septicemia . -
pubmed
Only 60
patients survived another 6 months because of general
debility and other diseases . -
pubmed
Twenty - eight ( 47 % ) of the remaining
patients had at least one recurrent episode of
AC . -
pubmed
A common
bile duct stone was demonstrated in 4
patients after ERCP and indicative signs were found in another 5 ( 10 % ) . -
pubmed
CONCLUSIONS : PTBD remains a good option in
patients with
septic AC who have severe coexisting disease and may be too ill to undergo an operation . -
pubmed
Fifty - five
patients were accrued ( phase I : 15 ; phase II : 40 ) and all are evaluable for response and toxicity : median age = 58 ( 40 - 72 ) ; PS = 1 ( 0 - 2 ) ; gender = 48
males , 7
females ; stages IIIA = 8 , IIIB = 19 , IV = 28 ; and histologies were
adenocarcinoma ( 29 ) , squamous ( 20 ) , large cell ( 6 ) . -
pubmed
Nosocomial outbreak of
Kluyvera cryocrescens bacteremia . -
pubmed
METHODS :
Human articular chondrocytes were isolated from the femoral head and tibial plateau of
patients undergoing knee joint replacement for
OA . -
pubmed
Blunt
injury of the innominate artery associated with a
bovine arch . -
pubmed
UNLABELLED : In
patients with
myocardial infarction (
MI ) , an expansion of the remote normal regions of the left ventricle is often observed . -
pubmed
RESULTS : The LV end - diastolic volume index was significantly larger in
patients with
MI without beta - blockers than in normal control subjects ( 101 + /- 22.5 vs. 61.6 + /- 12.8 mL x m(-2 ) ; P & lt ; 0.001 ) . -
pubmed
There was no significant difference in the heart rate x pressure product between the
patients with
MI without beta - blockers and the normal control subjects ( 8,229 + /- 1,503 vs. 8,311 + /- 1,311 mm Hg x min(-1 ) ) . -
pubmed
The K(mono ) in remote normal regions was significantly greater in
patients with
MI without beta - blockers even when compared with the highest K(mono ) on the anteroseptal wall of the left ventricle in normal control subjects ( 0.078 + /- 0.022 vs. 0.065 + /- 0.007 min(-1 ) ; P & lt ; 0.01 ) . -
pubmed
No significant difference in the LV end - diastolic volume index was found between the
MI patients with and without beta - blockers . -
pubmed
The levels of plasma
NO in
patients with
PIH were significantly lower than those in healthy pregnancy . -
pubmed
Short - term
depression at primary afferent synapses in
rat substantia gelatinosa region . -
pubmed
To study the short - term
depression at primary afferent synapses between Adelta fibers and substantia gelatinosa ( SG ) neurons in the spinal cord , transverse spinal cord slices with dorsal root attached were made from young
rats . -
pubmed
casei ) have been carried out using
strain ATCC 393 ( pLZ15- ) . -
pubmed
These tests showed that
strains of
ATCC 393 T obtained from independent public type - culture collections were significantly different from the plasmid - free ( pLZ15- )
strains of ATCC 393T. -
pubmed
Complete sequencing of the 16S rDNA of one representative
strain from each group revealed that strain
ATCC 393 T from culture collections was 99 % similar to
Lactobacillus zeae ATCC 15820 T and that the
strain so far considered as
L. - pubmed
All data obtained in this work indicate that the ancestral
strain of
ATCC 393 ( pLZ15- ) might never have been the
strain that is now available from culture collections . -
pubmed
While for young
patients , the diagnosis of
pituitary micro - adenoma and use of X - Knife radiosurgery should be very cautious , otherwise
hypopituitarism might be resulted . -
pubmed
Ventricular fibrillation in
hypothermic dogs . -
pubmed
Human ovarian cyst gps , which belong to the complex type of glycoform , comprise most of the structural units . -
pubmed
Axonal degeneration in
paraplegin - deficient mice is associated with abnormal mitochondria and impairment of axonal transport . -
pubmed
In several
neurodegenerative diseases ,
axonal degeneration occurs before neuronal
death and contributes significantly to
patients ' disability . -
pubmed
Paraplegin - deficient mice are affected by a distal
axonopathy of spinal and peripheral axons , characterized by
axonal swelling and degeneration . -
pubmed
Results of operative treatment of 60
patients with
pheochromoblastoma were analyzed . -
pubmed
In 8 ( 13.3 % )
patients with the spread
metastases revealed and they were directed to symptomatic therapy by their residence . -
pubmed
The
recurrence occurrence after primary operation performance is unfavorable prognostic feature : 55.8 % of such
patients were considered incurable . -
pubmed
PURPOSE : To evaluate the duration of the effect of intravitreal
triamcinolone acetonide on visual acuity in
patients with diffuse
diabetic macular edema . -
pubmed
METHODS :
Subjects were 31
patients ( 38 eyes ) with diffuse
diabetic macular edema who received an intravitreal injection of 20- to 25 - mg
triamcinolone acetonide . -
pubmed
CONCLUSIONS : The effect of an intravitreal injection of approximately 20- to 25 - mg
triamcinolone acetonide in
patients with diffuse
diabetic macular edema lasts approximately 7 to 8 months . -
pubmed
CONCLUSIONS :
Rhesus monkeys respond to either dietary L or Z supplementation with increases in serum
xanthophylls and MP , even after life - long
xanthophyll deficiency . -
pubmed
These
animals provide a potential model to study mechanisms of protection from
AMD . -
pubmed
A case of acute
gastrointestinal haemorrhage in a
patient with
systemic neurofibromatosis is presented . -
pubmed
Patients with systolic
heart failure and restrictive filling pattern show a lower exercise tolerance than their counterparts with non - restrictive filling . -
pubmed
This indicates a significant role of
diastolic dysfunction in the development of clinical symptoms in
patients with
left ventricular systolic impairment . -
pubmed
Progress in the understanding of
diastolic dysfunction may allow for better evaluation of prognosis and therapeutic efficacy and for monitoring of
patients with
systolic dysfunction . -
pubmed
A slice anatomy study was performed on 12 right wrists of unfixed
human cadavers by using the plastination technique . -
pubmed
Potentiation of the antitumoral activity of
gemcitabine and
paclitaxel in combination on
human breast cancer cells . -
pubmed
The purpose of this study was to evaluate the antitumoral activity of different
gemcitabine - based combination on an experimental model of
human breast cancer , in order to identify the most effective treatment and to provide a rationale for clinical investigations . -
pubmed
Mice bearing
CG5 human breast xenografts treated with
paclitaxel and
gemcitabine in combination showed a significant higher inhibition of
tumor growth ( approximately 70 % ) compared to that with either agent alone ( 25 % ) . -
pubmed
The opportunities to change the treatment of
ovarian cancer will require creative clinical trial design but the next decade promises to be filled the therapeutic advances for
patients with
ovarian cancer . -
pubmed
To date , glyceroneogenesis has only been described in
mammals but we demonstrate in this paper that it could exist in the invertebrate
Schistosoma mansoni , the parasitic
helminth transmitted by fresh water
molluscs and responsible for the major
human endemic disease ,
schistosomiasis . -
pubmed
Study of reaction norms showed that the genotypes from different
animal species are similarly plastic , but there are transgenic models in which adaptation to mechanics is not caused by
hypertrophy but by qualitative changes in gene expression . -
pubmed
OBJECT : Acute
respiratory failure has been observed in
patients after external immobilization for displaced
odontoid fractures . -
pubmed
The authors studied the frequency of respiratory deterioration in the acute management of displaced
Type II odontoid fractures to identify
patients at risk for
respiratory failure . -
pubmed
METHODS : The authors conducted a retrospective review of a consecutive series of 89
patients with
odontoid fractures who were treated over a 5 - year period to identify 53
patients with displaced
Type II odontoid fractures . -
pubmed
Of the 32
patients with posteriorly displaced
fractures , 13 experienced acute respiratory compromise , whereas only one of 21
patients with anteriorly displaced
fractures had respiratory difficulties ( p = 0.0032 ) . -
pubmed
CONCLUSIONS : Frequent respiratory deterioration during acute closed reduction of posteriorly displaced
Type II odontoid fractures was observed , whereas
respiratory failure in
patients with anteriorly displaced
fractures was rare . -
pubmed
PAH is one of the resulting deleterious effects in approximately 15 % of
SSc patients . -
pubmed
CONCLUSION :
Bosentan treatment was well tolerated in this cohort of
SSc patients with
interstitial lung disease and was effective for treatment of severe
PAH in the majority of
patients . -
pubmed
Atherosclerotic disease was discovered in 17 % of the
patients . -
pubmed
METHODOLOGY : Seventy - four of 281
rectal cancer patients , since the introduction of laparoscopic colorectal surgery in our hospital , have undergone laparoscopic rectal surgery . -
pubmed
CONCLUSIONS : Laparoscopic mesorectal excision with preservation of autonomic pelvic nerves for
rectal cancer patients including selected advanced lower
rectal cancer is favorable . -
pubmed
INTRODUCTION : Intermittent pneumatic mechanical compression is commonly applied to obviate venous stasis in
patients with increased risk of
thromboembolism . -
pubmed
Although a central aortic operation alone successfully reversed aortic - type
malperfusion in all three
patients , it was not effective for branch - type
malperfusion in five of six vascular territories . -
pubmed
Surgical fenestration did not successfully reverse branch - type
renal malperfusion in two
patients . -
pubmed
Modulation rate transfer functions in
bottlenose dolphins (
Tursiops truncatus ) with normal hearing and
high - frequency hearing loss . -
pubmed
The antirheumatic effect of
pirfenidone was compared with a positive control drug ,
oxyphenbutazone which is used in
patients suffering from
rheumatoid arthritis , in a double blind clinical trial in
humans . -
pubmed
No graft loss or
hyperthrophic scarring which may be seen at the apex of neovagina after Mc Indoe vaginoplasty was observed during the follow - up period and adequate neovaginal depth were obtained in both of the
patients . -
pubmed
We show that female
mice with defective DNA double - strand break repair had significantly increased frequencies of zygotes with sperm - derived
chromosomal aberrations after matings with wild - type males irradiated 7 days earlier with 4 Gy of ionizing radiation . -
pubmed
Urinary tract infections are a major source of morbidity among women , with the majority caused by uropathogenic
Escherichia coli . -
pubmed
There was a good outcome in the majority of
patients who presented with arterial gas
embolism and were treated with compression . -
pubmed
Review : intensified
patient care may improve adherence to lipid - lowering medication in primary or secondary prevention of
CV disease . -
pubmed
METHODS :
Rat models of
AC (
biliary tract obstruction+
E. - pubmed
RESULTS : Severe
liver tissue injury in
rats with
AC was evident as shown by pathological examination . -
pubmed
Quantitative risk assessment of
human campylobacteriosis related to the consumption of
chicken meat in two Italian regions . -
pubmed
Campylobacteriosis is the most frequently reported
zoonotic disease in
humans within the European Union . -
pubmed
The consumption of contaminated
chicken meat is considered one of the main sources of
human infection . -
pubmed
The authors developed a simulation model to quantitatively estimate the expected annual number of
human cases of
campylobacteriosis in the Italian regions of Abruzzo and Molise , due to the cross - contamination during the handling of
Campylobacter jejuni contaminated
chicken meat in domestic kitchen . -
pubmed
The expected percentage of
human population , experiencing
Campylobacter gastroenteritis episodes every year in Abruzzo e Molise regions , varied between 0.8 % and 1.8 % , according to the dose - response model . -
pubmed
With one ( 20 % , p & gt ; 0.05 ) exception none of the
children with
DCM were
overweight or had a family history of
diabetes . -
pubmed
All five ( 100 % )
children with
DCM had been given high cumulative dosage of
steroids 18 ( 78.3%)--without
DCM ( p & gt ; 0.05 ) . -
pubmed
The median age of
children with
DCM was greater [ 4.3 ( 12.7 - 18.0 ) vs. 7.0 ( 2.3 - 18.0 ) yr , p & lt ; 0.01 ] and duration of follow - up longer [ 5.3 ( 2.3 - 7.0 ) vs. 2.5 ( 0.7 - 7.3 ) yr , p & lt ; 0.05 ] . -
pubmed
Four
children ( 80 % ) with
DCM were pubertal ( p & lt ; 0.05 ) . -
pubmed
DCM is frequently observed in liver transplanted
children . -
pubmed
Albeit the
children with
DCM were given high cumulative dose of
steroids , were older , mostly were pubertal , and had longer duration of follow - up , we can not draw firm conclusions on effects of the risk factors on
carbohydrate metabolism because of the small sample size and relatively short duration of follow - up . -
pubmed
Unlike fasting measurements , OGTT can detect all
children with
DCM . -
pubmed
The stimulation of DCs by
bacterial strains was monitored by the production of
nitric oxide (
NO ) , and the colorimetric Greiss assay was used to quantify the level of
NO produced . -
pubmed
For example , in a
human , one of the reasons why the
habitual abortion is understood as the failure of the maternal immune system . -
pubmed
MATERIALS AND METHODS : Between September 2004 and September 2007 , 269 eligible
patients with a clinical suspicion of
prostate cancer referred to our department were randomized to an 8 - core lateral ( group 1 ) or a 12 - core lateral and parasagittal ( group 2 ) transrectal ultrasound guided prostate biopsy protocol . -
pubmed
PARTICIPANTS : Thirty - one eyes ( 31
patients ) underwent a variety of vitreoretinal procedures using the 27 - gauge transconjunctival MIVS system to treat
epiretinal membrane ( n = 10 ) ,
idiopathic macular holes ( n = 7 ) ,
diabetic vitreous hemorrhage ( n = 5 ) ,
vitreous opacity with suspicion of
intraocular lymphoma ( n = 4 ) , focal diabetic traction
retinal detachment ( n = 3 ) ,
macular traction syndrome ( n = 1 ) , and
macular edema secondary to central
retinal vein occlusion ( n = 1 ) . -
pubmed
Sixteen out of 26 ( 61.5 % )
GSD I patients in our study had suboptimal levels ( & lt;30 ng / ml ) of
25 - hydroxyvitamin - D (
25 ( OH ) D ) despite supplementation of
vitamin D and/or
vitamin D +
calcium based on WHO standards in 24/26 ( 92.3 % )
patients . -
pubmed
Pseudoaneurysms can be debilitating for
patients and occasionally life threatening . -
pubmed
Varicella - zoster virus (
VZV ) is a neurotropic
human alphaherpesvirus and the causative agent of
varicella and
herpes zoster . -
pubmed
Investigation of
VZV neuropathogenesis by
infection of
human dorsal root
ganglion xenografts in immunocompromised ( SCID )
mice has provided a novel system in which to examine
VZV neurotropism . -
pubmed
Experimental
infection with recombinant
VZV mutants with targeted deletions or mutations of specific genes or regulatory elements provides an opportunity to assess gene candidates that may mediate neurotropism and neurovirulence . -
pubmed
The SCID
mouse -
human DRG xenograft model may aid in the development of clinical strategies in the management of
herpes zoster as well as in the development of " second generation " neuroattenuated vaccines . -
pubmed
Endogenous
adenosine is released in asthmatic
patients ' lungs by inhaled allergen , however , its exact role in
asthmatic responses or the receptors mediating these responses has not been determined . -
pubmed
PURPOSE : To develop a standardized clinical grading system for the management of
patients with
vernal keratoconjunctivitis (
VKC ) and to identify the risk factors associated with a worsened outcome of the disease , including decrease of visual acuity and ocular complications development . -
pubmed
PARTICIPANTS : A total of 207 consecutive
patients with
VKC , referred to our Cornea and External Diseases Center from 1997 to 2007 , were included in the study . -
pubmed
The number of
relapses and number of
patients with
decreased visual acuity were also evaluated in the follow - up . -
pubmed
Sixteen
patients were classified as grade 0 ( absence of symptoms and no therapy ) ; 59
patients were classified as grade 1 ( presence of symptoms without
photophobia , occasional use of anti - allergic eye drop ) ; 74
patients were classified as grade 2 ( presence of symptoms including
photophobia , daily anti - allergic treatment ) ; 22
patients with
superficial punctuate keratopathy (
SPK ) were classified as grade 3 ( daily anti - allergic treatment associated with occasional topical
steroid ) ; and 36
patients were classified as grade 4 ( diffuse
SPK or
corneal ulcer ; pulsed high - dose topical
steroid ) . -
pubmed
Scanning electron microscopic study of trophozoite and
cyst stages of
Naegleria fowleri . -
pubmed
Whole trophozoites and
cysts of axenically cultivated
Naegleria fowleri were prepared for study of their surface morphology by scanning electron microscopy ( SEM ) . -
pubmed
METHODS : We performed BBDIR on 20 control
subjects and 13
patients with
acute ischemic stroke . -
pubmed
Suspicious intraplaque
hemorrhage and
calcification was demonstrated in 3
patients by CTI . -
pubmed
The in vivo anti - inflammatory properties of
CRBM-0244 were also investigated in a
guinea pig model of
allergic asthma . -
pubmed
Together , these findings provide key evidence regarding the mode of action of
CRBM-0244 in the lung , and point to new therapeutic strategies for modulating
inflammation in
patients with
asthma . -
pubmed
It then characterizes those chemicals using a chemical hazard - based framework that addresses persistence and bioaccumulation ,
human toxicity , and
human exposures . -
pubmed
We present a model for
ceratomyxosis - induced mortality in
O. - pubmed
The concern that endemically old and unique Australian vertebrate fauna might display high sensitivity to pesticides used for
locust control provoked examination of the
acute oral toxicity of the
organophosphorus pesticide
fenitrothion for the
fat - tailed dunnart ,
Sminthopsis crassicaudata ( Gould 1844 ) , and the
stripe - faced dunnart ,
S. - pubmed
By using the up - and - down method for determining
acute oral toxicity ,
S. - pubmed
Patients were stratified retrospectively into high- or low - risk groups according to risk factors for significant
carotid stenosis and
perioperative stroke :
peripheral vascular disease (
PVD ) , carotid bruit ,
diabetes mellitus , age & gt;70 years and/or history of
cerebrovascular disease . -
pubmed
CONCLUSION : In our cohort , selective screening of
patients aged & gt;70 years , with carotid bruit , a history of
cerebrovascular disease ,
diabetes mellitus or
PVD would have reduced the screening load by 40 % , with trivial impact on surgical management or neurological outcomes . -
pubmed
Our study aimed to examine
mental fatigue effects among 10 neurologically normal , athletically active
students undergoing typical
concussion testing . -
pubmed
SIGNIFICANCE : Neurologically intact and athletically active college
students demonstrate effects related to
fatigue after undergoing a typical sports
concussion assessment battery , including an increase in subjectively experienced
fatigue , a decrease in cognitive task performance accuracy and associated modulations in EEG activity . -
pubmed
One published randomized controlled trial ( RCT ) reported significant reductions of
gonorrhoea (
Neisseria gonorrhoeae ) [ rate ratio ( RR ) 0.46 , 95 % confidence interval ( CI ) 0.31 - 0.68 ] and
chlamydia (
Chlamydia trachomatis ) ( RR 0.38 , 95%CI 0.26 - 0.57 ) , but no effect on serologic
syphilis ( RR 1.02 , 95%CI 0.54 - 1.95 ) . -
pubmed
One observational study reported
genital ulcer disease (
GUD ) declines in sex workers , and two reported impact among male client populations for
N. - pubmed
Additional benefits may include impact on
STI and
HIV transmission at population level . -
pubmed
Clinical course of
children with
HIV associated thrombocytopenia . -
pubmed
RESULTS : 34
children ( 19.6 % ) out of 173 were found to have
thrombocytopenia . -
pubmed
After excluding three who had
pancytopenia associated
thrombocytopenia , records of 31
children ( 28 M , 3 F ) were further studied . -
pubmed
Cytotoxic activities and anti -
tumor - promoting effects of microbial transformation products of
prenylated chalcones from
Angelica keiskei . -
pubmed
Furthermore , the metabolite 13 exhibited inhibitory effect on
skin tumor promotion in an in vivo two - stage
mouse skin
carcinogenesis test based on
7,12 - dimethylbenz [ a ] anthracene (
DMBA ) as initiator , and with
TPA as promoter . -
pubmed
Thus , lack of therapeutic efficacy demands innovative treatment options for
patients with advanced
ACC . -
pubmed
A significant reduction in
tumor size was detectable in
NCIh295 tumor - bearing
mice after a single treatment with SSLD-1H7 ( 0.89 + -0.15 cm ; P=0.006 ) and a diminished efficacy for SSLD -
PEG+ ( 1.01 + -0.19 cm ; P=0.04 ) in comparison with untreated controls ( 1.5 + -0.0 cm ) . -
pubmed
We examined physiological biomarkers ( hemolymph
lactate ,
glucose , and protein concentrations ) of hypoxic stress in the
red swamp crayfish Procambarus clarkii from chronically hypoxic natural habitats and laboratory
hypoxia experiments . -
pubmed
clarkii to severe
hypoxia ( 1 mg / l DO ) , moderate
hypoxia ( 2 mg / l DO ) , or normoxic conditions ( control : DO>7.5 mg / l ) for 12 , 24 , and 48 h.
P. - pubmed
These results suggest that elevated hemolymph
lactate and
glucose concentrations are responses to acute
hypoxia in
P. - pubmed
Plasma marker proteins associated with the progression of
lung cancer in
obese mice fed a high - fat diet . -
pubmed
Interestingly , the protein abundances of ten proteins exhibited a synergistic effect when treated with HFD in
tumor - bearing
mice ( Group I ) . -
pubmed
In
SH patients , the mechanism of
atherosclerosis may be attributed to the
lipid abnormalities . -
pubmed
METHOD : The study enrolled 25
cases with
SH and 20 healthy controls . -
pubmed
Characteristics of
patients with unilateral and bilateral
Meniere ' s disease . -
pubmed
OBJECTIVE : To evaluate epidemiologic differences between
patients with unilateral and bilateral
Meniere ' s disease (
MD ) . -
pubmed
To delineate findings that might have implications as to the cause of
MD , we have studied rigidly selected
patient populations with unilateral and bilateral MD STUDY DESIGN : Prospective cohort . -
pubmed
MATERIALS AND METHODS :
Patients with a potential diagnosis of
MD underwent extensive evaluations ( audiometric , radiologic , and immunologic ) , and only
patients with
idiopathic MD were included in this study . -
pubmed
CONCLUSION :
Patients with bilateral
MD have a higher incidence of
migraines and of a family history of
MD . -
pubmed
Because it is a non - invasive and cost - effective method to measure and analyze hemodynamics , it would bring to physiologists very important diagnostic information for the continuous care of critical
patients with
hemodynamic disorders . -
pubmed
The role of the intestinal microbiota as a regulator of
autoimmune diabetes in animal models is well - established , but data on
human type 1 diabetes are tentative and based on studies including only a few study subjects . -
pubmed
Reduced
oestrogen levels in
women during the menopausal transition may therefore increase their risk of
hypertension and/or RAS - mediated changes to cerebrovascular or
AD pathology . -
pubmed
Macrophage depletion impairs corneal
wound healing after autologous transplantation in
mice . -
pubmed
METHODS : Autologous corneal transplantation model was used to induce
wound repair in
Balb / c mice . -
pubmed
Peritoneal macrophages were isolated from
Balb / c mice and transfused into conjunctiva to examine the recovery role of macrophages depletion on
wound healing after autologous corneal transplantation . -
pubmed
We describe the case of a 33 - year - old
man with a history of multiple minor
head injuries observed to harbour asymptomatic , bilateral cerebrospinal fluid - density collections over the cerebellar hemispheres . -
pubmed
The
cysts partially recurred , necessitating reopening of the burrholes , after which the
patient 's symptoms resolved entirely . -
pubmed
A
prolonged QTc syndrome was not uncommon in this cohort of asymptomatic
HIV - infected patients with good immunovirological control . -
pubmed
However , in vitro inhibitory activity against ten
human tumor cell lines showed that hydrolyzed
rutin exerted a more potent antiproliferative effect than
quercetin and
rutin on various
cancer cell lines , specially
glioma , and
ovarian and breast adenocarcinomas . -
pubmed
Pharmacokinetic analysis of
piperacillin administered with
tazobactam in
critically ill , morbidly obese surgical
patients . -
pubmed
PATIENTS : Nine morbidly obese (
body mass index [ BMI ] 40.0 kg / m2 or higher ) hospitalized
patients admitted to the
trauma and surgical intensive care service who were treated with
piperacillin - tazobactam between December 15 , 2010 , and April 18 , 2012 . -
pubmed
About half of the world 's population is currently infected with
Helicobacter pylori , which is involved in the development of several
gastro - duodenal pathologies . -
pubmed
The oral administration of
piperine ( 1.12 mg / kg ) during 23 days in
rats seemingly interfered with the
toxicity of
aflatoxins , decreasing
hepatic injuries and the leukocyte depletion in experimentally intoxicated animals . -
pubmed
Study population was composed of incident
patients with advanced
chronic kidney disease (
glomerular filtration rate & lt;30 mL / min ) related to
type 2 diabetes in a tertiary hospital from Gran Canaria ( Spain ) during a period of 2 years . -
pubmed
Of 78 eligible
patients , 21.8 % had
normoalbuminuria , 20.5 % had
microalbuminuria , and 57.7 % had
proteinuria . -
pubmed
BACKGROUND :
Cutaneous infection by
Mycobacterium ulcerans , also known as
Buruli ulcer (
BU ) , represents the third most common
mycobacterial disease in the world after
tuberculosis and
leprosy . -
pubmed
This is a prospective study including 40
patients with benign and malignant
tumours of orbital , paraorbital and other sites giving rise to unilateral
proptosis . -
pubmed
Thus
nasal obstruction is the commonest ENT presenting complains in these
patients . -
pubmed
Seasonal dynamics of
Thelandros maplestonei infections in the wall lizard ,
Hemidactylus flaviviridis in Imphal Valley , Manipur , India . -
pubmed
The influence of seasons on the population dynamics of the nematode ,
Thelandros maplestonei infection in
Hemidactylus flaviviridis was studied for one annual cycle in the Imphal Valley , Manipur , India . -
pubmed
maplestonei
infections in
H. - pubmed
Preclinical efficacy of
melatonin in the amelioration of
tenofovir nephrotoxicity by the attenuation of oxidative stress , nitrosative stress , and
inflammation in
rats . -
pubmed
Identifying an agent that prevents
tenofovir disoproxil fumarate (
TDF)-induced
renal injury can lead to better tolerance to
TDF , and a more effective treatment can be achieved in
HIV infected patients . -
pubmed
The present study is aimed at investigating whether
melatonin , a potent antioxidant and anti - inflammatory agent , protects against
TDF nephrotoxicity in
rats . -
pubmed
Some
rats received 600 mg / kg
body weight TDF by gavage for 35 days , while others received once daily 20 mg / kg
body weight melatonin i.p . -
pubmed
Results :
Melatonin pretreatment protected the
rats against
TDF nephrotoxicity both histologically and biochemically . -
pubmed
Conclusions :
Melatonin pretreatment protects
rats from
tenofovir - induced damage to proximal tubular mitochondria by attenuating oxidative stress , nitrosative stress , and
inflammation . -
pubmed
This suggests that it may be useful in ameliorating
TDF nephrotoxicity in
humans . -
pubmed
Impact of magnetic resonance imaging on computed tomography - based treatment planning and
acute toxicity for
prostate cancer patients treated with intensity modulated radiation therapy . -
pubmed
PURPOSE : To evaluate rectal and bladder dosimetric and clinical
acute toxicity endpoints for prostate
patients treated with intensity modulated radiation therapy ( IMRT ) using magnetic resonance images ( MRI ) registered to computed tomographic ( CT ) simulation images versus CT alone . -
pubmed
MATERIALS AND METHODS : The charts of 155 consecutive
prostate cancer patients at our institution from 2004 to 2008 were reviewed . -
pubmed
[ Effect of acupotomy intervention on cervicomuscular apoptosis in
cervical spondylosis rabbits ] . -
pubmed
Short daily versus conventional hemodialysis for
hypertensive patients : a randomized cross - over study . -
pubmed
BACKGROUND : Treatment of
end stage renal disease patients with short daily hemodialysis has been associated with an improvement in blood pressure . -
pubmed
STUDY DESIGN , SETTING AND PARTICIPANTS : We undertook a randomized cross - over trial in adult
hypertensive patients with
ESRD treated with conventional hemodialysis to determine : 1 ) if short - daily hemodialysis is associated with a reduction in
systolic blood pressure after a 3 - month blood pressure optimization period and ; 2 ) the potential mechanism(s ) of blood pressure reduction . -
pubmed
CONCLUSIONS :
Patients treated with short daily , compared to conventional hemodialysis , have similar blood pressure control on fewer anti -
hypertensive medications . -
pubmed
The sensitivity of the different titles of antinuclear antibodies was determined in a group of 136
patients with a diagnosis of
autoimmune rheumatic disease , and the specificity was determined in a group of 118
patients with other
rheumatic diseases . -
pubmed
Given that the bioactive lipid
sphingosine 1 - phosphate is involved in cardiovascular pathophysiology , and since lipid accumulation and
inflammation are hallmarks of
calcific aortic stenosis , the role of
sphingosine 1 - phosphate on the pro - inflammatory / pro - osteogenic pathways in
human interstitial cells from aortic and pulmonary valves was investigated . -
pubmed
Liberian man being treated for
Ebola in Texas dies . -
pubmed
Thus , the initiation of an international
tumor registry may aid with the management of
patients presenting with
ACNs . -
pubmed
Blastomycosis in a postpartum
dog . -
pubmed
Transplacental
infection with Blastomyces dermatitidis is rare in
humans and unknown in the
dog . -
pubmed
Brain abscess due to
Trueperella bernardiae . -
pubmed
We present the case of a
brain abscess caused by a combination of rare organisms (
Trueperella bernardiae and
Peptoniphilus harei ) in a patient with
chronic suppurative otitis media that had been complicated by the presence of a
cholesteatoma . -
pubmed
All
patients received
tacrolimus ( dose , 0.1 mg / kg /
body weight , in 2 divided doses ) . -
pubmed
These four
patients were all
adolescents or young adults ( age 13 - 22 years ) , experienced preceding
gastrointestinal symptoms , and had serological and/or bacterial evidence of recent
Campylobacter jejuni enteritis . -
pubmed
Patients were randomized to receive BST - CarGel treatment or
microfracture alone , and followed standardized 12 - week rehabilitation . -
pubmed
RESULTS : Blinded MRI analysis demonstrated that BST - CarGel -treated
patients showed a significantly greater treatment effect for lesion filling ( P = 0.017 ) over 5 years compared with
microfracture alone . -
pubmed
A 80 - year - old male
patient admitted to the emergency department with gross
hematuria /
clot retention and right
flank pain . -
pubmed
METHODS : In the present study , a consecutive sample of suspected
patients with
CAP was underwent CUS , CXR , and chest computed tomography ( CT ) scan . -
pubmed
RESULTS : 30
patients with
CAP were enrolled ( 93.3 % male with mean age of 63.8 + - 18.3 years ) . -
pubmed
Magnesium sulphate can prolong pregnancy in
patients with severe early - onset
preeclampsia . -
pubmed
OBJECTIVE : To assess whether long - term use of
magnesium sulphate prolongs pregnancy in
patients with severe early - onset
preeclampsia . -
pubmed
RESULTS : Long - term group showed significant prolongation of pregnancy compared with the control group ( 9.2 + - 7.9 versus 16.6 + - 9.3 d , log - rank test , p = 0.021 ) , which was also observed in
patients with severe
preeclampsia occurring before 28 weeks ' gestation ( n = 11 , 4.5 + - 5.2 versus 13.2 + - 6.8 d , log - rank test , p = 0.035 ) . -
pubmed
CONCLUSIONS : Long - term use of
magnesium sulphate prolonged pregnancy in
patients with severe early - onset
preeclampsia and can help alleviate progression of
preeclampsia . -
pubmed
ED TREATMENT : in n.18/182 subjects ( 9.9 % ) there was a concomitant
hypotestosteronemia ; these
patients were treated only with
testosterone replacement ; this treatment was efficacious ( IIEF-5 total score & gt;=22 ) in 8/18
subjects ( 44.4 % ) . -
pubmed
Retraction Note : Central macular thickness in
patients with
type 2 diabetes mellitus without clinical
retinopathy . -
pubmed
Hunter syndrome is generally considered to have two manifestations : an attenuated form and a severe form ; in the latter , the
person has pronounced
cognitive decline . -
pubmed
Children with the severe phenotype show
developmental delay and changes in behaviour patterns at about 18 months to 4 years of age . -
pubmed
We studied the pharmacokinetics and efficacy of the broad - spectrum
triazole isavuconazole for the treatment of experimental
invasive pulmonary aspergillosis (
IPA ) in persistently
neutropenic rabbits . -
pubmed
There were significant concentration - dependent reductions of residual fungal burden ( log CFU / gram ) and of organism - mediated
pulmonary injury , lung weights , and
pulmonary infarct scores in ISA40- and ISA60 - treated
rabbits in comparison to those of UC ( P & lt ; 0.001 ) . -
pubmed
delta - CNTX - Pn1a does not cause any apparent
toxicity to
mice , when intracerebroventricularly injected ( 30 mug ) . -
pubmed
In this study , we evaluated the antinociceptive effect of delta - CNTX - Pn1a in three
animal pain models and investigated its mechanism of action in acute
pain . -
pubmed
In the inflammatory
pain model , induced by carrageenan , delta - CNTX - Pn1a restored the nociceptive threshold of
rats , when intraplantarly injected , 2 h and 30 min after carrageenan administration . -
pubmed
Dengue is the most prevalent
arboviral disease in
humans and a major public health problem worldwide . -
pubmed
RESULTS : Partnerships for maternal history of low
birth weight ( OR : 41.1 ; 95 % CI : 5.5 - 306.7 ) were found ;
prematurity ( OR : 12.0 ; 95 % CI : 1.5 - 94.3 ) , history of
eclampsia ( OR : 5.8 ; 95 % CI : 1.9 - 17.4 ) , one to three prenatal controls ( OR : 5.7 ; 95 % CI : 2.6 - 12.3 ) , multiple gestation ( OR : 4.7 ; 95 % CI : 1.3 - 17.0 ) and
tobacco consumption ( OR : 3.8 ; 95 % CI : 1.5 - 9.8 ) , not being a teenager ( OR : 0.3 ; 95 % CI : 0.1 - 0.6 ) , and not having a short birth interval ( OR : 0.2 ; 95 % CI : 0.1 - 0.7 ) . -
pubmed
Sixty - eight Dutch
FA patients have been transplanted since 1972 . -
pubmed
OBJECTIVE : Case report of a
patient with
angioid streaks ,
peau d'orange ,
comet tail lesions ,
choroidal neovascularisation and presumed
pseudoxanthoma elasticum (
PXE ) . -
pubmed
One hundred
patients had distant
metastases , of which the liver was the only location in 54
patients . -
pubmed
Overall survival rates for
CRC patients with liver
metastases who underwent resection were 30 % at 2 years and 17 % at 5 years , and the mean survival rate was 1.4 years . -
pubmed
CONCLUSIONS : Both the mean survival rate of our
CRC patients with resectable
liver metastases and the 5 - year survival rate of these patients are lower than global averages . -
pubmed
LLC
animals were allowed to develop
tumors for 4 wk to induce
cachexia . -
pubmed
This study aimed to determine whether genetic polymorphisms of genes in the
vitamin D pathway are associated with treatment responses to
pegylated interferon (
PEG - IFN)-based therapy in
patients with chronic
HCV infection . -
pubmed
The innate immunity of
guinea pigs against highly pathogenic
avian influenza virus infection . -
pubmed
In contrast to the highly virulent phenotype of
H5N1 in
humans and many animal models ,
guinea pigs do not typically display signs of severe disease in response to
H5N1 virus infection . -
pubmed
Furthermore , we show that
guinea pig complement is involved in viral clearance , the regulation of
inflammation , and cellular apoptosis during
influenza virus infection of
guinea pigs . -
pubmed
This work uncovers features of the
guinea pig innate immune response to
influenza that may render
guinea pigs resistant to highly pathogenic
influenza viruses . -
pubmed
METHODS : RADG was performed in
patients with clinical Stage I
gastric cancer , and reconstruction was performed using Delta . -
pubmed
CONCLUSION :
Cystic brain destruction might occur prenatally and neurodevelopment of gyration and differentiation of the cortical layers in the developing brain could be affected by
sulfite accumulation early during the second trimester in
ISOD patients . -
pubmed
RESULTS : CB ( n = 264 ) compared to C ( n = 109 )
patients were younger , less likely performance status ( PS ) impaired , and more likely with
liver metastases . -
pubmed
For
patients with right- vs. left - sided
tumors , C ( but not CB)-treated
patients had higher adjusted risk for progression ( HR = 1.715 , 95 % CI 1.108 , 2.653 ; p = 0.015 ) . -
pubmed
Patients with right - sided
tumors treated with C were at higher risk for
disease progression than
patients with left - sided
tumors . -
pubmed
Accordingly , in this study , we established an
inflammatory bowel disease visceral pain model in
rat by enema with a mixed solution of 5 %
trinitrobenzenesulfonic acid and 50 %
ethanol . -
pubmed
Patients and methods :
Patients undergoing
cataract extraction and lens replacement ( CELR ) were eligible . -
pubmed
Post - thrombotic syndrome (
PTS ) is the most common long - term complication after
deep vein thrombosis (
DVT ) developing in up to 70 % of the
patients . -
pubmed
Methods : We performed a retrospective review of 47
patients performed single level posterior cervical laminoforaminotomy for
cervical radiculopathy between 2004 and 2012 . -
pubmed
We divided these
patients into two groups , Group A : 27
patients for ruptured disc and Group B : 20
patients for
foraminal stenosis and analyzed the demographic factors , amount of medial facetectomy , postoperative instability with
neck pain and clinical outcomes . -
pubmed
Thirteen
patients complained of postoperative
neck pain for 2 months . -
pubmed
Edible fungal
strains of Ascomycota (
Aspergillus oryzae ,
Fusarium venenatum ,
Monascus purpureus ,
Neurospora intermedia ) and Zygomycota (
Rhizopus oryzae ) phyla were screened and selected for their protein production yield . -
pubmed
The appropriate target blood pressure ( BP ) in elderly
patients with
hypertension remains uncertain . -
pubmed
The incidence of
adverse drug reactions related to excessive BP lowering was lower in
patients & lt;75 years than in
patients & gt;=75 years ( 0.73 vs 1.02 % , P = 0.0461 ) . -
pubmed
Our laboratory has previously reported DIAm
sarcopenia in
rats and
mice characterized by DIAm
atrophy and a reduction in maximum specific force at 24 months of age . -
pubmed
The purpose of this study in Fischer 344
rats was to evaluate if there are sex - related differences in DIAm
sarcopenia , and if such differences translate to a functional impact on Pdi generation across motor behaviors and maximal Pdi ( Pdimax ) elicited by bilateral phrenic nerve stimulation . -
pubmed
In both males and females , DIAm
sarcopenia was apparent in 24 - month - old
rats with a ~30 % reduction in both maximum specific force and the cross - sectional area of type IIx and/or IIb fibers . -
pubmed
MATERIALS AND METHODS : A prospective study was carried out on forty eyes of
patients having
signs and symptoms of
dry eye . -
pubmed
Patients were evaluated on the basis of
dry eye - related symptom score , tear film break - up time ( TFBUT ) , tear meniscus height ,
fluorescein ocular surface staining score ( FOSS ) , and the Schirmer 's test at the end of 2 , 4 , 6 , and 12 weeks and their values were compared with the baseline . -
pubmed
CONCLUSION : Nearly 2 %
rebamipide ophthalmic solution provided relief in the symptoms of
patients having
dry eyes . -
pubmed
The present study explores treatment outcomes for DRG
subjects who were
paresthesia - free vs. those who experienced the sensation of
paresthesia , as well as the factors that predicted
paresthesia - free analgesia . -
pubmed
Outcomes of
subjects who were
paresthesia - free were compared to those who experienced
paresthesia - present therapy at 1 , 3 , 6 , 9 , and 12 - month follow - ups . -
pubmed
RESULTS : The percentage of
subjects with
paresthesia - free
pain relief increased from 16.4 % at 1 - month to 38.3 % at 12 - months . -
pubmed
Paresthesia - free
subjects generally had similar or better outcomes for
pain severity ,
pain interference , quality of life , and mood state as subjects with
paresthesia - present stimulation . -
pubmed
CONCLUSIONS : Some DRG
subjects achieved effective
paresthesia - free analgesia in the ACCURATE trial . -
pubmed
We hypothesized that resting - state functional connectivities of habenula would show differences in neuroanatomical correlates of the evaluative system ( prefrontal cortex , habenula ) of
patients with
GAD . -
pubmed
We obtained 22
patients with
GAD and 21 HCs , matched for gender , age , and years of education . -
pubmed
Patients with
GAD demonstrated enhanced connectivities in the bilateral premotor cortex , right ventrolateral prefrontal cortex , medial frontal cortex , as well as the left orbitofrontal cortex , and reduced connectivities in the left posterior cingulate cortex , and right pulvinar . -
pubmed
The purpose of this study was to investigate the prevalence of
SLD - resistant
strains and its specific mutations in drug - resistant
Mycobacterium tuberculosis clinical isolates , and to acknowledge the transmission pattern of
SLD resistance strains in Hebei . -
pubmed
These analyses characterized the relationships between
risankizumab exposures and key efficacy and safety variables in Japanese
patients with moderate - to - severe
plaque psoriasis ,
GPP , or
EP following treatment with 75 or 150 mg subcutaneous doses at weeks 0 , 4 , and every 12 weeks thereafter . -
pubmed
METHODS : Risankizumab average plasma concentrations ( Cavg ) were correlated with probabilities of achieving efficacy end points ( PASI 75 , PASI 90 , PASI 100 , and sPGA 0/1 ) using data from Japanese
patients ( N = 225 ) and non - Japanese
patients ( N = 1678 ) with moderate - to - severe
plaque psoriasis enrolled in global trials , or a Japan Phase 2/3 trial . -
pubmed
CONCLUSIONS : Overall ,
risankizumab 150 mg maximized efficacy , including PASI 100 response , in
Japanese patients with
psoriasis with no apparent relationship between exposure and evaluated safety variables . -
pubmed
Herein , we report a 36 - year male
patient presenting with right - sided flank
pain and microscopic
hematuria . -
pubmed
Methods : The clinical characteristics and relevant variables were retrospectively analyzed in a total of 270
NDMM patients diagnosed between November 2009 and May 2018 . -
pubmed
Effects of voluntary and forced exercises on motor function recovery in
intracerebral hemorrhage rats . -
pubmed
Motor
paralysis is a severe consequence of
intracerebral hemorrhage (
ICH ) that reduces
patient quality of life . -
pubmed
Rehabilitation is beneficial for
stroke patients . -
pubmed
We aimed to clarify the effect of voluntary and forced exercises for functional recovery in
ICH rats . -
pubmed
OBJECTIVE : To explore the inhibitory effects and molecular mechanisms of nano - realgar on the migration , invasion and
metastasis of
mouse breast cancer cells . -
pubmed
A
murine breast cancer metastasis model was established , administered nano - realgar for 32 days and monitored for
tumor growth and
metastasis by an in vivo optical imaging system . -
pubmed
Meanwhile , nano - realgar effectively suppressed the abilities of
tumor growth ,
metastasis and angiogenesis in the
murine breast cancer metastasis model in a time- and dose - dependent manner . -
pubmed
In vivo combination therapy with
PENAO and
gefitinib was non - toxic to
mice and significantly delayed
tumour growth and prolonged survival . -
pubmed
At 20 days after treatment ,
tumours from the combination treated
mice were significantly smaller than those from untreated and single drug treated
mice . -
pubmed
With decreasing mortality rates , a higher number of
patients are impacted by long - term
neuropsychiatric sequelae , such as
cognitive deficits ,
depression ,
anxiety , and
sleep - wake disorders . -
pubmed
Neurostimulants are centrally acting medications used to assist in restoring these neurotransmitter abnormalities and are pharmacologic options to ameliorate symptoms in
post - TBI patients . -
pubmed
Large , well - powered studies have not been performed to validate their use in
patients with
TBI , leaving uncertainty for these agents ' place in therapy . -
pubmed
This review provides clinicians with a summary of the available literature on neurostimulants following
TBI to guide appropriate usage to help improve
patients ' symptoms and optimize safety . -
pubmed
Cell growth was determined using nude -
mouse transplanted
tumor experiments . -
pubmed
miR-141 - 3p was down - regulated in
breast cancer specimens and could serve as an independent prognostic factor for predicting overall survival in
breast cancer patients . -
pubmed
In addition , overexpression of miR-141 - 3p could inhibit
hypoxia - induced cell migration and impede
human breast cancer MDA - MB-231 cell growth in vivo . -
pubmed
Mortality of
NSCLC patients increases with the development of a
metastatic lesion compared to when the
tumor is localized ; however , the exact mechanism for what causes
NSCLC cells to metastasize in the context of environmental toxicant exposure has yet to be fully elucidated . -
pubmed
The prognostic value of fQRSTa in
patients with
aortic stenosis undergoing surgical aortic valve replacement . -
pubmed
BACKGROUND : Surgical aortic valve replacement ( sAVR ) is the ultimate therapy for severe
aortic stenosis (
AS ) in suitable
patients . -
pubmed
In this study , we aimed to investigate the prognostic value of fQRSTa in
patients with severe symptomatic
AS undergoing sAVR . -
pubmed
METHODS : A total of 372
patients with severe degenerative
AS who underwent successful sAVR were included in this retrospective study . -
pubmed
CONCLUSION : fQRSTa was related with poor prognosis in
patients with
AS undergoing sAVR . -
pubmed
Here , using proteomic analysis of
Drosophila larval midguts during degradation , we identify a group of proteins with peptidase activity , suggesting a role in autophagy - dependent cell
death . -
pubmed
Hemodynamic instability caused by hyperdynamic circulation , systemic fluid retention ,
infection , and
bleeding is frequently observed postoperatively in severely cirrhotic
patients . -
pubmed
Preoperative optimization , including correction of
coagulopathy and poor nutrition , is therefore crucial for minimizing the predictive
postoperative complications in those
patients . -
pubmed
Recently , the model for
end - stage liver disease ( MELD ) score has been gaining attention for its reliability in identifying
patients at high risk for open heart surgery . -
pubmed
We investigated the relationship between
AD ( assessed by CMR ) and
coronary artery disease (
CAD ) severity ( assessed by the SYNTAX score ) in
patients with premature
CAD . -
pubmed
We recruited 125
patients with
CAD confirmed by coronary angiography ( males were < 55 years old and females < 65 years old ) . -
pubmed
We excluded
patients with significant
aortic disease or contraindications to CMR . -
pubmed
The severity of
CAD in young
patients is associated with decreased
AD , especially at the level of the
AR . -
pubmed
The main objective of this research was to study the impact of chemotherapy on the cognitive function of
patients with locoregional
breast cancer . -
pubmed
Excessive
vascular remodeling has been shown in
hypertensive patients . -
pubmed
In a
mouse model of
angiotensin II - induced
hypertension , we show that aortas exhibit increased medial thickening ,
fibrosis , and features of EndMT . -
pubmed
The symptoms associated with the
syndrome can vary greatly from individual to
individual and within the family . -
pubmed
Rauwolfia and
breast cancer . -
pubmed
Pathogenesis of
rat colon
carcinomas induced by
N - methyl - N - nitrosourea . -
pubmed
Well - developed
tumors from
rats receiving
MNU generally presented grossly as
polyps ; histologically , as invasive
adenocarcinomas that had not metastasized . -
pubmed
These
tumors resembled their
human counterparts . -
pubmed
Focal
epithelial atypias were found in grossly
normal mucosa both from
rats that had not yet developed
tumors and from
tumor - bearing
rats . -
pubmed
It was concluded that most invasive
carcinomas in this
rat model originate in foci of
epithelial atypia , which are found with increasing frequency in the flat mucosa during treatment with
MNU , but that some
carcinomas also arise from adenomatous epithelium . -
pubmed
Testosterone concentrations in plasma of dairy
cows with
ovarian cysts . -
pubmed
Testosterone in plasma was measured by radioimmunoassay in
cows with
ovarian cysts and in
cows during the estrous cycle . -
pubmed
Concentrations of
testosterone in plasma ( 60.8 + /- 2.7 pg / ml ; mean + /- standard error ) in
cows with
ovarian cysts were variable but within the range in
cows during the estrous cycle . -
pubmed
In
cows with
ovarian cysts , concentrations of
testosterone in plasma declined within 24 h following
prostaglandin F2 alpha and tended to increase by 9 days following
gonadotropin releasing hormone . -
pubmed
Comparative
tumor - inhibitory and anti -
bacterial activity of soluble and particulate glucan . -
pubmed
A soluble fraction of particulate glucan was prepared and evaluated for its anti -
tumor and anti -
bacterial activity . -
pubmed
Survival data demonstrated that intravenous administration of soluble or particulate glucan prolonged survival of A / J and C57BL/6J
mice with subcutaneous
tumor implants . -
pubmed
As regards to
bacterial infections , soluble and particulate glucan decreased
renal necrosis in
S. - pubmed
However , accumulating evidence indicates that
human gamma / delta+ T - cells frequently recognize
bacterial ligands as well as certain
tumor cells . -
pubmed
Total repair for
truncus arteriosus using an external conduit was performed in 12
patients from 1978 through 1989 . -
pubmed
Replacement of an external conduit was performed due to a
conduit stenosis in 2
children and 1 infant , 10 years and 2 months , 7 years and 9 months , and 1 year and 8 months after the total repair , respectively . -
pubmed
16
children with
atopic dermatitis and 4
nonatopics were skin tested with flavourings and perfumes . -
pubmed
The preoperative MR studies of 25
patients with surgically proved
medulloblastomas were retrospectively reviewed in order to characterize these
neoplasms with regard to their MR signal intensity , size , location , and appearance after contrast enhancement . -
pubmed
In the
patients who received
gadopentetate dimeglumine , the fraction of
tumor volume showing enhancement was found to be less than one third in two cases , between one third and two thirds in four cases , and greater than two thirds in five cases . -
pubmed
From January ' 81 to April ' 91 , one shot transarterial infusion therapy and transcatheter arterial embolization therapy were performed in five
patients with
recurrences of
hepatocellular carcinomas after surgery . -
pubmed
In a study of prognosis in node - negative
breast carcinoma , we investigated 293 T2N0M0
patients treated by mastectomy and axillary dissection with a median follow - up of 19.8 years . -
pubmed
Recurrence at 20 years was not significantly different for
patients with invasive duct ( 34 % ) and lobular ( 42 % )
carcinoma . -
pubmed
Women with special types ( medullary , mucinous , papillary , etc ) of
carcinoma had a 25 % chance of
recurrence . -
pubmed
Subsequent contralateral
breast carcinoma was diagnosed in 29
patients , and four of these were fatal , accounting for only 4.6 % of
breast carcinoma deaths . -
pubmed
Thirty - two
patients ( 10.9 % ) developed a
nonmammary malignant neoplasm (
NMMN ) after the ipsilateral
breast carcinoma , and 69 % of these lesions were fatal . -
pubmed
This is the first reported case of documented transmission of
S pyogenes , causing a
toxic shocklike syndrome in an emergency medical technician . -
pubmed
The technique of total pelvic exenteration with simultaneous bowel and urinary reconstruction is described as a surgical option for the management of
pelvic sarcoma in adults and for highly selected
patients with other types of advanced
pelvic malignancy . -
pubmed
The surgical technique is presented in detail as performed in a 43 - year - old
man who presented with extensive primitive
pelvic sarcoma . -
pubmed
In adult
sows ,
ketamine induced profound
analgesia , which was not obtained in young
pigs ; this difference in potency could not be related to pharmacokinetic differences between young and adult swine. -
pubmed
injection of
fluorocitrate in
mice resulted in
seizures after an average latency of 15 s , while intracerebroventricular ( i.c.v . ) -
pubmed
[ Hemodynamics of the greater and lesser circulation in
patients with
hypertension ] . -
pubmed
Based on a study of the hemodynamics of the greater and pulmonary circulation by direct methods in 117
patients with essential
hypertension it has been demonstrated that changes in the
stroke volume are implicated in the mechanism of the interregulation of the greater and pulmonary circulation . -
pubmed
The lesions , clinically and histopathologically , resemble
lepromas which develop at the site of experimental inoculation of
Mycobacterium leprae in armadillos . -
pubmed
VFP goggles were used in the treatment of 7
patients with
migraine headache . -
pubmed
Of 50
migraine headaches recorded , 49 were rated by the
patient as being helped and 36 as being stopped by using the VFP goggles . -
pubmed
Treatment reduced the median duration of
headache in all
patients . -
pubmed
A comparison of some effects of
phosphine ,
hydrogen cyanide and
anoxia in the
lesser grain borer ,
Rhyzopertha dominica ( F. ) ( Coleoptera : Bostrychidae ) . -
pubmed
The effects of
phosphine ,
hydrogen cyanide and
anoxia on levels of
ATP ,
pyruvate and
lactate in
Rhyzopertha dominica are compared . -
pubmed
Fusions were performed with or without prior transformation of PBL with
Epstein - Barr virus (
EBV ) . -
pubmed
It may reduce long - term mortality in
patients with known
coronary artery disease and may slow or reverse the progression of
atherosclerosis . -
pubmed
The beneficial effects , taken together with the low cost of
nicotinic acid therapy and the relative freedom from serious side effects , have made
nicotinic acid the agent of choice for the treatment of many
patients with
hyperlipidemia . -
pubmed
In this report of 211
patients ,
malignant melanomas in BANS sites had a 4.6 % poorer 5 - year cumulative survival rate ( 88.9 % BANS , 93.5 % non - BANS ; p = 0.35 ) . -
pubmed
Salmonella enteritidis bacteremia in childhood . -
pubmed
We have reviewed the clinical course of 32
children with
Salmonella enteritidis bacteremia and compared them with 135 children with
acute gastroenteritis caused by
S. - pubmed
A preoperative
barium esophagogram and esophageal manometry in an adult
patient with an
H - type congenital tracheoesophageal fistula revealed the typical
esophageal motor abnormalities previously described following operative repair of
esophageal atresia in infants . -
pubmed
The specificity of
leishmaniasis I.H.A.T. in albino
rats experimentally infected with
Toxoplasma gondii and
Hymenolepis nana . -
pubmed
[
Leukodystrophy in
children ] . -
pubmed
Unilateral acute , fulminating
renal papillary necrosis with
Escherichia coli septicemia . -
pubmed
The early effects of
metabolic acidosis on renal metabolism in the
rat . -
pubmed
The early renal metabolic response was studied in
rats made
acidotic by oral feeding of
ammonium chloride . -
pubmed
Ammonia production by the same slices was also increased at 2 hr , but thereafter fell and at 6 hr had decreased to levels which , although higher than those of the control , were lower than those obtained from the
rats acidotic for only 2 hr . -
pubmed
There was no correlation between in vitro gluconeogenesis and
ammonia production by kidney slices from
rats during the first 6 hr of
acidosis , but after 48 hr of
ammonium chloride feeding , these two processes were significantly correlated . -
pubmed
There was never any difference in
pyruvate or
lactate levels or
lactate :
pyruvate ratios between control and
acidotic rats . -
pubmed
Fifty - six
patients with
chronic allergic rhinitis were selected for a randomized double - blind study comparing
oxatomide with a placebo . -
pubmed
In a survey of 75
patients at 6 - 11 weeks gestation ,
fetomaternal hemorrhage (
FMH ) was detected by significant rises ( greater than 2 S.D. ) -
pubmed
Hormonal and hemodynamic responses to
vena caval obstruction in fetal
sheep . -
pubmed
This paper presents an alternative method of demarcating regions of interest over the myocardium after administration of
123I - heptadecanoic acid to
patients with
coronary artery disease . -
pubmed
When 382 urine specimens were analysed by the modified test which is described in detail , there were neither false negatives nor false positives for
infections with Escherichia , Klebsiella , Citrobacter or
Proteus species . -
pubmed
The efficacy and safety of
bromocriptine mesylate ( 5 to 7.5 mg per day for up to 24 weeks ) were studied in 22 clinical trials involving 226
patients who had
amenorrhea /
galactorrhea associated with
hyperprolactinemia and no demonstrable
pituitary tumor . -
pubmed
Galactorrhea was significantly ( at least 75 % ) reduced in 76 % of the 187
patients after an average treatment tome of 6.4 weeks , and was completely suppressed in 58 % after 12.7 weeks . -
pubmed
Several
patients experienced
hypotension , but only 1 discontinued therapy because of it . -
pubmed
Developmental changes of the hypogastric
ganglion associated with the differentiation of the reproductive tracts in the
mouse . -
pubmed
In these
animals , the hypogastric
ganglion which is thought to innervate the internal genitalia was examined at birth . -
pubmed
The number of
ganglion cells was significantly larger in prenatally
DES - exposed male and TP - exposed female
mice than that of controls . -
pubmed
The suppressive effect of
PVA on the host defense to experimental
infection with
Escherichia coli was weaker than those of HB and BV . -
pubmed
A very - low - calorie formula diet ( Cambridge diet ) for the treatment of
diabetic - obese patients . -
pubmed
Prolonged blockade of
nitric oxide synthesis in gravid
rats produces sustained
hypertension ,
proteinuria ,
thrombocytopenia , and
intrauterine growth retardation . -
pubmed
OBJECTIVE : Our purpose was to test the hypothesis that chronic inhibition of
nitric oxide synthesis in pregnant
rats can produce a
preeclampsia - like syndrome . -
pubmed
CONCLUSION : Chronic inhibition of
nitric oxide synthesis in gravid
rats leads to sustained
hypertension ,
proteinuria ,
thrombocytopenia , and
intrauterine growth retardation , providing a simple
animal model for
preeclampsia . -
pubmed
Mutatox is a new
genotoxicity bioassay which uses as the endpoint the bioluminescence produced on reversion of a dark
strain of the marine bacterium
Vibrio fischeri + /- S9 . -
pubmed
For screening , Mutatox provides many advantages over the
Salmonella typhimurium ( Ames ) assay : it requires minimal
sterility , employs a shorter incubation period , and does not require culture maintenance . -
pubmed
For the purpose of this study , 1,107 electrocardiograms ( ECGs ) from
patients who had undergone cardiac catheterization were used to train and test neural networks for the diagnosis of
myocardial infarction . -
pubmed
A twenty eight year - old
man with anomalous pulmonary venous drainage from the right lung to the inferior vena cava (
scimitar syndrome ) underwent surgical treatment . -
pubmed
Cytogenetic characterization of the
human prostate cancer cell line
P69SV40 T and its novel tumorigenic sublines
M2182 and
M15 . -
pubmed
Cytogenetic studies of a
SV40 T antigen immortalized
human prostate epithelial cell line (
P69SV40 T ) and its increasingly tumorigenic
tumor sublines , designated
M2182 and
M15 , were done with GTG - banding and multicolor fluorescence in situ hybridization ( FISH ) . -
pubmed
Those unique to M15 were a der(16)t(16;19 ) and -Y. Chromosome imbalances resulting from numerical and/or structural abnormalities in the
tumor sublines involved several chromosome regions that have previously been implicated in
human prostate cancer , such as loss of Xp , Y , 3p ( M2182 and M15 ) , 16q ( M15 ) , and gains for 5q ( M2182 ) and 8q ( M2182 and M15 ) . -
pubmed
Collectively , the characterization of these lines should assist with the localization of chromosome regions , and possibly genes , that are important in the development and progression of
human prostate cancer . -
pubmed
STUDY DESIGN : In this study the motor scores of 62 consecutive acute
spinal cord - injured patients were retrospectively reviewed . -
pubmed
METHODS : Sixty - two consecutive adult
patients admitted within 7 days of acute
spinal cord injury between April , 1983 , and September , 1992 , were evaluated . -
pubmed
There were 38
patients with cervical and thoracic lesions , 12
patients with
dorso - lumbar lesions , and 12
patients with lower
lumbar lesions . -
pubmed
BACKGROUND AND PURPOSE :
Cerebral amyloid angiopathy (
CAA ) occurs as a
sporadic disorder in aged
humans , as a frequent component of
Alzheimer ' s disease , or in
hereditary cerebral hemorrhage with
amyloidosis (
HCHWA ) . -
pubmed
The primary histological locus of
cerebral amyloid deposition varies in aged
humans and in different
species of
nonhuman primates . -
pubmed
In aged
rhesus monkeys ,
amyloid deposition occurs most frequently in
senile plaques , whereas in aged
squirrel monkeys CAA is more common . -
pubmed
These observations support the utilization of the
monkeys as models to study
CAA . -
pubmed
The patient , a 31 year - old
man , arrived to the hospital complaining of
abdominal pain and
vomiting , but then developed a clinical picture of low
intestinal obstruction . -
pubmed
Effect of
steroid therapy on parameters of
peripheral autonomic dysfunction in
leprosy patients with
acute neuritis . -
pubmed
Recent electrophysiological studies on peripheral autonomic dysfunction in
leprosy patients show a high prevalence of
autonomic dysfunction as measured by abnormal vasomotor reflexes ( VMR ) and absent sympathetic skin response ( SSR ) . -
pubmed
Since there is evidence that small fiber function may be the most reversible component in
neuropathies , we measured the effect of
steroid treatment on autonomic parameters together with motor and sensory functions in
leprosy patients with acute
neuritis . -
pubmed
In this study , the authors examined
PG ' s effects on the
toxicity of
ethanol in the primary culture of
rat regenerations . -
pubmed
Junctional rhythm occurred in 1 to 3
patients in all other groups with the exception of the
Edr -
Atr(1 ) group in which no
cardiac arrhythmias occurred . -
pubmed
CONCLUSIONS : On the basis of the present results , anticholinesterase - anticholinergic combinations should be avoided in
patients having a
long QT interval syndrome or a
prolonged QT interval from other causes . -
pubmed
Long - term treatment of
chronic schizophrenia with
risperidone : an open - label , multicenter study of 386
patients . -
pubmed
An open - label , multicentre study was conducted to assess the long - term efficacy and safety of
risperidone in
patients with
chronic schizophrenia . -
pubmed
Extrapyramidal symptoms ( scores on the
Extrapyramidal Symptom Rating Scale ) tended to decrease in severity or remained unchanged over the course of
risperidone treatment ; 27.7 % of
patients required antiparkinsonian medication during the study . -
pubmed
An experiment was carried out with a
Culex quinquefasciatus strain with resistance genes called " Quibu " , this
strain was pressured with 3
organophosphorous insecticides :
malathion ,
chlorpyriphos , and
pyrimiphos - methyl . -
pubmed
Although much is now known about the pathophysiology and biology of this parasite in the
cat , the practical application and rapid development of this information to daily practice has led to
confusion . -
pubmed
A 16 - year - old
boy presented with
hypertension and sudden
abdominal pain after minor blunt
abdominal trauma . -
pubmed
Pheo should be considered in
hypertensive pediatric
patients with a history of blunt
abdominal trauma . -
pubmed
Mycoplasma pneumoniae : a cause of
coma in the absence of
meningoencephalitis . -
pubmed
That
Mycoplasma pneumoniae encephalopathy can occur in the presence of a normal CSF examination is less well appreciated . -
pubmed
The authors report two
children who presented with
coma and normal CSF findings in whom a diagnosis of acute
Mycoplasma pneumoniae infection was made . -
pubmed
Recent techniques in neurovascular bundle preservation could lead to an overall improvement in postoperative quality of life without compromising
cancer control in the appropriately selected
patient . -
pubmed
Five
patients with advanced
HCC secondary to
chronic hepatitis and
cirrhosis underwent pretreatment and posttreatment MR examination on a 1.5 T MR scanner following systemic chemotherapy . -
pubmed
Three of these
patients had no or minimal change of
tumor volume ; however , there was an increase in
tumor necrosis in follow - up MR image . -
pubmed
One
patient of five with no change in
tumor necrosis had no response and died at 3 months . -
pubmed
Serial MR images showed increased irregular
necrosis of advanced
HCC after systemic chemotherapy , but stable volume , in
patients who responded clinically to systemic chemotherapy . -
pubmed
PATIENTS : Five alert ,
critically ill adults receiving mechanical ventilatory support . -
pubmed
RESULTS : Logistic regression demonstrated that a
murine blastocyst formation rate & gt;or=53.3 % in 50 % hydrosalpinx fluid ( OR = 16.6 , 95 % CI 2.4 - 116.1 , P = 0.005 ) and
patient age ( OR = 0.778 , 95 % CI 0.61 - 0.99 , P = 0.045 ) were independent predictors of
IVF outcome . -
pubmed
More information is needed on late
toxicity that influences the quality of life for these
patients . -
pubmed
pylori resulted in complete endoscopic and histological remission of
MALT - lymphoma in 9 out of 10
patients as assessed 6 months after this eradication . -
pubmed
A 15 - year - old
girl presented with a history of
cough ,
fever for five months and
breathlessness of two days duration . -
pubmed
[ Slow , chronic , organic and functional
adrenal insufficiencies in the
child ] . -
pubmed
[ On experimental
ethylene glycol renal lithiasis in the male and female
rat ] . -
pubmed
Oxygen is the first treatment the
patient needs in order to overcome
hypoxemia . -
pubmed
With the exception of
hypoxemic patients who also need
oxygen , the administration of beta-2 agonists using metered - dose inhalers with a holding chamber was found to be as effective as administration with nebulizers , and in some studies , even more effective and safer . -
pubmed
With the exception of the most severe
asthma attacks , high - dose inhaled
corticosteroids are at least as effective as oral
corticosteroids in controlling moderate - to - severe
asthma attacks especially in
children . -
pubmed
METHODS : Adenoid tissue cells from 13
atopic and 8 non - atopic
children were cultured and stimulated with
ionomycin and
4beta - phorbol 12 - myristate 13 - acetate . -
pubmed
Atrial fibrillation affects approximately 2 million people in the United States and is a common comorbidity among
patients with
heart failure . -
pubmed
Clinical studies indicate that the benefits of the beta - blocker
carvedilol in
patients with
heart failure extend to
patients with
heart failure complicated by
atrial fibrillation . -
pubmed
The results of the
Carvedilol in
Atrial Fibrillation Evaluation ( CAFE ) trial provide support that
carvedilol has incremental benefit when added to
digoxin for the management of
atrial fibrillation in
patients with
heart failure . -
pubmed
Additional recent studies suggest that
carvedilol may be useful in managing postsurgical
atrial fibrillation and also may prevent
recurrence of
atrial fibrillation among
patients who undergo cardioversion . -
pubmed
In an effort to examine the utility of the metabonomic approach for discriminating sera from women with
EOC from healthy controls , we performed
( 1 ) H - NMR spectroscopic analysis on preoperative serum specimens obtained from 38
patients with
EOC , 12
patients with benign
ovarian cysts and 53 healthy women . -
pubmed
In addition , we analyzed the regions of NMR spectra that most strongly influence separation of sera of
EOC patients from healthy controls . -
pubmed
CONCLUSIONS : Postoperative adjuvant therapy with edrecolomab restores the in vivo deficient immune responses of
patients with resected Dukes ' C
CRC despite its clinical ineffectiveness in recent randomized adjuvant trials . -
pubmed
BACKGROUND :
Oral warts , caused by
human papillomavirus (
HPV ) , and
oral hairy leukoplakia (
OHL ) caused by
Epstein - Barr virus (
EBV ) , are common oral manifestations in
HIV - infected persons . -
pubmed
METHODS : Biopsies were taken from lesion - positive and adjacent lesion - negative sites of
HIV+ persons with
oral warts or
OHL and lesion - negative sites from
HIV+ persons who were oral
HPV or
EBV DNA - positive ( matched controls ) . -
pubmed
Legionella pneumophila is an important opportunistic pulmonary pathogen that causes
Legionaires'diseases . -
pubmed
An understanding of these roles will inform studies of their contribution to fertility and
infertility in
man . -
pubmed
Living donor liver transplantation ( LDLT ) has become a well - recognized treatment modality for
patients with
end - stage liver disease . -
pubmed
Hepatic arterial
thrombosis was encountered in 3
patients . -
pubmed
This has increased liver transplantations in the presence of limited
cadaver grafts and has decreased the
patient mortality in the waiting list . -
pubmed
A 76 - year - old
woman with a history of total thyroidectomy for a
thyroid carcinoma at the age of 63 was admitted to our hospital for the treatment of a
renal rupture induced by a
tumor of about 3 cm in diameter . -
pubmed
Adult
mice were ovariectomized as models of experimental
osteoporosis . -
pubmed
This third section focus on those drugs used to treat
mycobacterial infections (
Mycobacterium tuberculosis ) ,
fungal infections ( Candida species , Aspergillus species ) , and
viral infections ( herpes ,
hepatitis , and
influenza ) . -
pubmed
We studied 164
patients with
Peyronie ' s disease , 34 of whom have clinical symptoms of
erectile dysfunction . -
pubmed
Dopplerographic signs of
venoocclusive dysfunction were seen also in
patients with minor
erectile disorders ( 55.4 % ) . -
pubmed
Calendar period and age at
HIV seroconversion strongly influenced
AIDS and
death rates . -
pubmed
In 33
patients ( 53 % ) some other
pelvic prolapse was corrected . -
pubmed
In the last revision , 58
patients ( 93 % ) proved to be objectively continent and 4 ( 6.5 % ) showed a notable improvement in their
incontinence . -
pubmed
A
dystocia and caesarean section model to characterize uteroplacental
prostaglandin concentrations associated with retained placenta in dairy
cattle . -
pubmed
METHODS : Between 1995 and 2002 , three
women and one
man aged from 13 to 58 years were treated for
chylothorax after thoracic surgery . -
pubmed
RESULTS : These
patients had : a pulmonary and hepatic cystectomies , a resection of the mediastinal
tumor , an Akyama oesophagectomy and a resection of four left
pulmonary metastases . -
pubmed
In the
patient who had had an oesophagectomy ,
chylothorax persisted after re - operation . -
pubmed
Tamarix gallica , a hepatic stimulant and tonic , was examined for its ability to inhibit
thioacetamide (
TAA)-induced hepatic oxidative stress ,
toxicity and early
tumor promotion response in male
Wistar rats . -
pubmed
Pretreatment of
rats orally with
Tamarix gallica extract ( 25 and 50 mg / kg
body weight ) prevented
TAA - promoted oxidative stress and
toxicity . -
pubmed
Our data suggests that
Tamarix gallica is a potent chemopreventive agent and may suppress
TAA - mediated hepatic oxidative stress , toxicity , and
tumor promotion response in
rats . -
pubmed
Endometrial damage and apoptosis in
rats induced by
dichlorvos and ameliorating effect of antioxidant
vitamins E and C. -
pubmed
We aimed to investigate the effect of subchronic administration of
dichlorvos (
DDVP ) on endometrium and to evaluate ameliorating effects of a combination of
Vitamins E and C against
DDVP toxicity in the
rat . -
pubmed
Clinical utility of " blind placement " prostatic stent in
patients with
benign prostatic obstruction : a prospective study . -
pubmed
OBJECTIVES : To assess the efficacy and safety of two versions of a blind placement temporary prostatic stent in the treatment of
patients with
benign prostatic obstruction . -
pubmed
METHODS : Tissue samples from 110
patients with
GERD ( n = 43 ) ,
BE ( n = 20 ) , and
BC ( n = 47 ) were obtained in routine upper GI endoscopy . -
pubmed
OBJECTIVE : To understand the role of
epilepsy surgery in
children with generalized or bilateral findings on preoperative scalp EEG . -
pubmed
METHODS : From our pediatric
epilepsy surgery series , we identified 50
patients in whom 30 to 100 % of preoperative
epileptiform discharges ( ictal , interictal , or both ) were generalized or contralateral to the side of surgery . -
pubmed
RESULTS : All
patients had severe refractory
epilepsy and an
epileptogenic lesion on brain MRI . -
pubmed
At last follow - up ( median 24.0 months ) , 72 % of
patients were
seizure - free , 16 % had marked improvement with only brief episodes of staring or
tonic stiffening , and 12 % were not improved . -
pubmed
Postoperative
seizure - free rate did not differ from that in a comparison group of similar
patients who matched the study group except for their high percentage ( 70 to 100 % ) of ipsilateral ictal and interictal
epileptiform discharges on preoperative EEG . -
pubmed
CONCLUSIONS :
Epilepsy surgery may be successful for selected
children and
adolescents with a congenital or early - acquired
brain lesion , despite abundant generalized or bilateral
epileptiform discharges on EEG . -
pubmed
Tilarginine in
patients with acute
myocardial infarction and
cardiogenic shock . -
pubmed
OBJECTIVE : To determine whether the presence of
tumour at a free serosal surface was independently associated with pelvic
recurrence or survival in
patients who had a resection for clinicopathological stage B or stage C rectal
cancer and who had not received adjuvant therapy . -
pubmed
RESULTS : In 665
patients with stages B or C
tumour , 35 ( 5.3 % ; CI 3.7 - 7.2 % ) had
tumour at a free serosal surface . -
pubmed
Adjuvant therapy for premenopausal
patients with early
breast cancer . -
pubmed
PURPOSE OF REVIEW : Current topics on adjuvant therapy for premenopausal
patients with
breast cancer are reviewed . -
pubmed
RECENT FINDINGS : The Early
Breast Cancer Trialists ' Collaborative Group overview showed that
women under 50 received a remarkable benefit from postoperative chemotherapy and endocrine therapy . -
pubmed
The impact of chemotherapy - induced
amenorrhea on
patient outcome remains to be defined . -
pubmed
SUMMARY : There are a number of unresolved issues in terms of the optimal use of chemotherapy and endocrine therapy in premenopausal
patients with
breast cancer . -
pubmed
We examined the hypotheses that elderly
individuals with
GAD will have elevated salivary
cortisol levels compared to nonanxious subjects , and that elevated
cortisol levels in
GAD will be associated with measures of symptom severity . -
pubmed
The Effect of
Cromolyn Sodium and
Nedocromil Sodium Administered by A pressurized Aerosol with A spacer Device on Exercise - Induced
Asthma in
Children . -
pubmed
BACKGROUND : The ability of
risedronate to prevent and/or treat orchidectomy - induced
osteoporosis in male
rats was studied . -
pubmed
BACKGROUND :
Human bocavirus (
HBoV ) can be found in a substantial proportion of children with
respiratory tract diseases . -
pubmed
The relative importance of
HBoV in
viral respiratory tract illnesses is not yet well known . -
pubmed
OBJECTIVE : In this study , we looked for
HBoV in pediatric patients to determine the incidence of
HBoV as single
infection and compared it with other commonly found respiratory viruses to describe the clinical differences associated with
HBoV infections in children . -
pubmed
We studied the frequency of
HBoV and 15 other respiratory viruses in nasopharyngeal aspirates and compared the clinical course of the
infections caused by
HBoV with those caused by other common respiratory viruses . -
pubmed
Clinical differences were observed between
HBoV and
respiratory syncytial virus ( RSV ) infections ( children were older and
bronchiolitis less frequent ) , adenovirus (
fever less frequent in
HBoV group ) , and
rhinovirus - associated infections ( less
hypoxia in HBoV group ) . -
pubmed
CONCLUSIONS :
HBoV was the fourth most frequent single virus after
RSV , rhinovirus , and
adenovirus in children hospitalized because of
respiratory infection . -
pubmed
METHODS : We measured the heart rate and affect of 17 adolescent recovering
anorexic patients and 40 healthy age - matched controls during two conditions of the Stress Induced Speech Task ( SIST ): Free Association and Stress Task . -
pubmed
DISCUSSION : Although the physiological stress response of recovering adolescent anorexic
patients was similar to controls , the psychological response of partially and fully weight - restored
anorexic adolescents appears similar to that of acutely anorexic
adolescents . -
pubmed
One major complication occurred ( 5.8 % ): perforation of the hepaticojejunostomy in a
patient with recurrent
choledocolithiasis , which was successfully resolved surgically . -
pubmed
Inhibiting glycosphingolipid synthesis ameliorates
hepatic steatosis in
obese mice . -
pubmed
SUBJECT : A 67 - year - old
male with
intractable back pain due to advanced
lumbar spondylosis , with a history of advanced
Parkinson ' s Disease requiring two deep brain stimulators . -
pubmed
CONCLUSIONS : Intravitreal
triamcinolone is superior to observation for treating
vision loss associated with
macular edema secondary to
CRVO in
patients who have characteristics similar to those in the SCORE -
CRVO trial . -
pubmed
Although this
patient had normal plain films and computed tomography of the spine ,
her disease was first visualized by magnetic resonance imaging . -
pubmed
The multitude of publications leads to an evident and consistent conclusion : breasts reconstructed with an overly long vertical incision all suffer the same
deformity characterized by a
banana or squash - shaped breast . -
pubmed
Studies in the preclinical
animal models of
arthritis as well as
RA were examined critically and the data are presented . -
pubmed
RESULTS : Most of the single nucleotide polymorphisms ( SNPs ) showed no significant interaction with
E coli exposure for both
eczema and
allergic sensitization . -
pubmed
We present the case of a
woman born with
transposition of the great arteries , who was surgically repaired with the Mustard technique . -
pubmed
BACKGROUND : Severe outcomes have been described for both
Plasmodium falciparum and
P. - pubmed
Thoracic vertebral cavernous hemangioma in a
schizophrenic patient -- case report . -
pubmed
A 55 - year - old
man presented with
gait disturbance ,
incontinence , and
back pain . -
pubmed
Schizophrenic patients have diminished sensitivity to
pain or other symptoms , so neurological symptoms may become severe . -
pubmed
The
patient had a rare association of
vertebral hemangioma and
hepatic hemangioma , which may be a chance occurrence . -
pubmed
Pancreatitis and
cholangitis due to
cytomegalovirus in a
patient with
hyperimmunoglobulin E syndrome . -
pubmed
Twenty - eight ( 21 F ; 7 M ; mean age 34.2 + - 8.2 )
migraine and 15 ( 11 F ; 4 M ; mean age 35.9 + - 8.9 ) healthy
subjects were recruited in a double - blind , placebo - controlled , cross - over trial . -
pubmed
Furthermore , in
migraineurs who developed
migraine after
GTN , a significant facilitation in temporal summation of
pain was detected 60 ' , 120 ' and 180 ' after drug intake when compared to
patients without clinical response . -
pubmed
In
migraineurs the susceptibility to develop
migraine attack after
GTN administration seems to be a specific trait of a subgroup of
patients linked to a supersensitivity of the
pain system to
GTN . -
pubmed
MATERIALS AND METHODS : We prospectively examined 77
thyroid nodules in 60
patients undergoing ultrasound - guided fine needle aspiration biopsy ( FNAB ) . -
pubmed
The value of
99mTc - tetrofosmin brain SPECT in predicting survival in
patients with
glioblastoma multiforme . -
pubmed
In the present study , we set out to investigate the prognostic value of
( 99m ) Tc - tetrofosmin brain SPECT in
patients with
glioblastoma multiforme . -
pubmed
METHODS : We prospectively studied 18
patients ( 13
men , 5
women ; mean age + - SD , 60.8 + - 7.79 y ) who were operated on for
glioblastoma multiforme . -
pubmed
Although
patients with near - total
tumor resection who were younger than 60 y survived longer , the difference did not reach statistical significance . -
pubmed
CONCLUSION :
( 99m ) Tc - tetrofosmin brain SPECT may be an independent prognostic factor in
patients with
glioblastoma multiforme . -
pubmed
Macrophage
depression ( injection of
gadolinium chloride associated with a decrease in
metastasis number ) decreased serum concentration of tissue inhibitor , but it did not attain the control level observed in intact
mice . -
pubmed
Thirty nine
intrabony defects in 21
patients were treated with Fortoss Vital ( Biocomposites , Staffordshire , UK ) . -
pubmed
Syringohydromyelia in
horses : 3 cases . -
pubmed
The presenting complaints , clinical , gross pathological , and histopathologic findings of 2 cases of
syringomyelia and 1 case of
hydromyelia in
horses are described . -
pubmed
METHODS : We undertook a retrospective review of all
patients undergoing endoluminal stenting for
CD strictures at our institution from 2001 to 2010 . -
pubmed
CONCLUSIONS : Endoluminal stenting of CD
strictures is a safe and effective alternative to surgery which can provide lasting benefit in select
patients . -
pubmed
Chiropractic management of a 40 - year - old female
patient with
Meniere disease . -
pubmed
OBJECTIVE : The purpose of this case report is to describe the chiropractic management of a
patient with
Meniere disease . -
pubmed
CLINICAL FEATURES : A 40 - year - old
woman presented with a diagnosis of
Meniere disease including a 2 - month history of
vertigo and a 16 - month history of left - sided
tinnitus ,
low - frequency hearing loss , and
aural fullness . -
pubmed
The
patient 's other symptoms included left - sided
neck pain ,
temporomandibular joint pain , and
headaches . -
pubmed
Within 2 weeks of treatment , the
patient 's
tinnitus had resolved ; and all other symptoms ( including
vertigo ) were improved . -
pubmed
The
patient 's
headaches ,
neck pain , and
vertigo were subsequently resolved within 3 months of treatment . -
pubmed
CONCLUSION : This case report suggests that chiropractic care , including upper cervical spinal manipulation and soft - tissue therapy , may be beneficial in treating some
patients with
Meniere disease . -
pubmed
The impact of cardiac resynchronization therapy in an end - stage
heart failure patient with a left ventricular assist device as a bridge to recovery . -
pubmed
METHODS : Groups of
rats were defined by the presence of
inflammation , surgical intervention , and/or the type of general anesthetic used for a 3 - h period of anesthesia . -
pubmed
What are the options for anticoagulation needs in dialysis for
patients with
heparin - induced
thrombocytopenia ? -
pubmed
However , here we report the cases of two
children with
congenital cholesteatoma which disappeared spontaneously during the follow - up period . -
pubmed
We report the case of a 61 - year - old
man with an
angiosarcoma of the carotid artery . -
pubmed
Antibacterial activity was evaluated against that of reference
strains of
Staphylococcus aureus ,
Staphylococcus epidermidis ,
Streptococcus pneumoniae ,
Escherichia coli and
Pseudomonas aeruginosa . -
pubmed
Enteric disease in
dogs naturally infected by a novel
canine astrovirus . -
pubmed
Infection by a novel
canine astrovirus was associated with
gastroenteritis in two
dogs . -
pubmed
We report the successful management of a female
patient who developed postoperative
thrombotic thrombocytopenic purpura (
TTP ) after an uneventful laparoscopic oophorocystectomy . -
pubmed
The
patient underwent uneventful laparoscopic surgery for
ovarian cystoma . -
pubmed
One hour after completion of surgery , the
patient suddenly went into
shock , with her blood pressure dropping to 60/40 mmHg . -
pubmed
It is important to bear in mind the possibility of postoperative
TTP in
patients with unexplained
hemorrhagic shock after uneventful surgery . -
pubmed
Although we expected
brain defects , we were astonished to discover that the knockdown
zebrafish embryos were actually lacking blood and suffered from defective hemoglobin production . -
pubmed
The review describes modern diagnostic criteria for
delirium in
patients in ICU . -
pubmed
OBJECTIVES : To analyze the relationship between gender , age ,
injury - related variables and rehabilitation outcomes in
patients with
spinal cord injury (
SCI ) . -
pubmed
Patients were described according to age , gender , etiology of
SCI , neurological classification , medical complications , American
spinal injury association ( ASIA ) classification , length of rehabilitation stay and spinal cord independence measure ( SCIM ) . -
pubmed
In 3
patients presenting with massive
hematuria after urinary diversion , an
iliac artery pseudoaneurysm was found on imaging studies . -
pubmed
All
patients were successfully treated with a covered stent to exclude the
pseudoaneurysm and the arteriovesical
fistula . -
pubmed
We studied the effectiveness and safety of
spironolactone in
adults with newly diagnosed
systolic heart failure in clinical practice . -
pubmed
We identified all
adults with newly diagnosed
heart failure , left ventricular ejection fraction of & lt;40 % , and no previous
spironolactone use from 2006 to 2008 in Kaiser Permanente Northern California . -
pubmed
We excluded
patients with baseline serum
creatinine level of & gt;2.5 mg / dl or a serum
potassium level of & gt;5.0 mEq / L. We used Cox regression with time - varying covariates to evaluate the independent association between
spironolactone use and
death , hospitalization , severe
hyperkalemia , and
acute kidney injury . -
pubmed
Among 2,538 eligible
patients with a median follow - up of 2.5 years , 521
patients ( 22 % ) initiated
spironolactone , which was not associated with risk of hospitalization ( adjusted hazard ratio 0.91 , 95 % confidence interval 0.77 to 1.08 ) or
death ( adjusted hazard ratio 0.93 , confidence interval 0.60 to 1.44 ) . -
pubmed
Mycobacterium tuberculosis (
Mtb ) is a causative agent of
tuberculosis (
TB ) disease , which has affected approximately 2 billion people worldwide . -
pubmed
MATERIALS AND METHODS : Thirty - six
patients ( 32 male , and 4 female ; mean age , 29.8 years ) with
acute deltoid ligament injury who had undergone MRI participated in this study . -
pubmed
OBJECTIVE : To study whether synchronous electrical stimulation of the larynx could be helpful for improving voice quality in
patients with
dysphonia due to
unilateral recurrent laryngeal nerve paralysis (
URLNP ) . -
pubmed
Intravenous
cobinamide versus
hydroxocobalamin for acute treatment of severe
cyanide poisoning in a
swine (
Sus scrofa ) model . -
pubmed
Our objective is to compare the time to return of spontaneous breathing in
swine with acute
cyanide - induced
apnea treated with intravenous
hydroxocobalamin , intravenous
cobinamide , or saline solution ( control ) . -
pubmed
CONCLUSION : Both
hydroxocobalamin and
cobinamide rescued severely
cyanide - poisoned
swine from
apnea in the absence of assisted ventilation . -
pubmed
The purpose of this case report is to remind busy practicing physicians to keep spontaneous
renal thromboembolism in differential diagnosis in a
patient with
acute abdomen . -
pubmed
For every 100 patients treated with rtPA , there is a gain of 69.17 QALYs and of $ 408,419 over the lifetime of 100 treated
patients with
acute ischemic stroke . -
pubmed
CONCLUSIONS : This new analysis demonstrates a significant savings associated with the use of rtPA for
patients with
stroke and provides great support for the increased systematic use of rtPA in the state of South Carolina for patients with
acute ischemic stroke . -
pubmed
Logistic regression analysis was performed to estimate odds ratios ( ORs ) and their 95 % confidence intervals ( CIs ) for two - time vaccination against
measles and
rubella viruses as mandatory vaccinations and at least one - time vaccination against
mumps and
varicella - zoster viruses as optional vaccinations . -
pubmed
UNLABELLED : Aim / Materials and Methods : In order to develop better drugs against
non - small cell lung cancer (
NSCLC ) , we screened a variety of compounds and treated the
human lung adenocarcinoma cell line
A549 with different drug concentrations . -
pubmed
ACF treatment significantly decreased
tumor size and
tumor spots on lung surface of
tumor - bearing
mice . -
pubmed
METHODS : Eight
Parkinson disease (
PD )
patients with
apraxia , 11
patients without
apraxia , and 8 healthy
volunteers were enrolled . -
pubmed
PD patients with
apraxia did not have similar facilitation . -
pubmed
MAIN FINDINGS : We describe two
children with extratemporal pharmacoresistent
epilepsy , slowly progressive gray matter volume loss over several years , and evidence of
central nervous system inflammation . -
pubmed
CONCLUSIONS : These
patients illustrate a novel presentation of a subacute inflammatory central nervous system process with
epilepsy and progressive
cortical volume loss , supporting the role of sequential brain imaging in
children with
epilepsy . -
pubmed
The percentages of
patients with spherical equivalents within + -1.00 and + -0.50 diopters of
emmetropia were 100 % ( 29 eyes ) and 75.9 % ( 22 eyes ) , respectively , in the iDesign group and 96.7 % ( 29 eyes ) and 70.0 % ( 21 eyes ) , respectively , in the WaveScan group . -
pubmed
Patients ' demographics , types of
orbito - ocular tumor and their presentation were recorded . -
pubmed
Because of that , laboratorial diagnosis of acute undifferentiated
febrile illness during epidemic periods is frequently directed towards these viruses , which may eventually hinder the detection of other circulating flaviviruses , including the
Saint Louis encephalitis virus (
SLEV ) , which is widely dispersed across the Americas . -
pubmed
One of them was a triple co -
infection with
DENV-1 . -
pubmed
This is the first report of
SLEV molecular identification in
MT . -
pubmed
AIMS / HYPOTHESIS : The aim of this study was to determine the incidence and incidence rate trends for
type 1 diabetes mellitus in
children aged 0 - 14 years , Australia - wide , from 2000 to 2011 . -
pubmed
RESULTS : A total of 11,575 cases ( 6,049 boys and 5,526
girls ) of childhood
type 1 diabetes mellitus were registered between 2000 and 2011 , giving a mean incidence of 23.6 per 100,000 person - years ( 95 % CI 23.2 , 24.0 ) . -
pubmed
To compare patterns of associations of changes in mental and physical health dimensions of health - related quality of life ( HRQoL ) over time with
relapse occurrence and changes in Expanded Disability Status Scale ( EDSS ) scores in
patients with
relapsing multiple sclerosis (
RMS ) . -
pubmed
BACKGROUND : The monovalent
meningococcal A conjugate vaccine ( PsA - TT , MenAfriVac ) was developed for use in the "
meningitis belt " of sub - Saharan Africa . -
pubmed
Sensory and autonomic deficits in a new humanized
mouse model of
familial dysautonomia . -
pubmed
Outcomes After Arthroscopic Treatment of
Femoroacetabular Impingement for
Patients With Borderline
Hip Dysplasia . -
pubmed
PURPOSE : To compare outcomes after hip arthroscopy for
femoroacetabular impingement ( FAI ) in borderline dysplastic (
BD )
patients compared with a control group of nondysplastic
patients . -
pubmed
High rate of missed
HIV infections in individuals with indeterminate or negative
HIV western blots based on current
HIV testing algorithm in China . -
pubmed
It remains unclear if China 's current
HIV antibody testing algorithm misses a substantial number of
HIV infected individuals . -
pubmed
Of 196 specimens with indeterminate or negative results on
HIV western blot ( WB ) retrospectively examined by
HIV-1 nucleic acid test ( NAT ) , 67.57 % ( 75/111 ) of indeterminate
WB samples , and 16.47 % ( 14/85 ) of negative WB samples were identified as NAT positive . -
pubmed
The rate of
HIV-1 infections missed by China 's current
HIV testing algorithm is unacceptably high . -
pubmed
In vivo and in vitro evaluation of the effects of
Urtica dioica and swimming activity on
diabetic factors and pancreatic beta cells . -
pubmed
METHODS : Adult WKY male
rats were randomly distributed in nine groups : intact control ,
diabetic control ,
diabetic + 625 mg / kg , 1.25 g / kg UD , diabetic + 100 mg / kg
Metformin ,
diabetic + swimming ,
diabetic + swimming 625 mg / kg , 1.25 g / kg UD , and diabetic +100 mg / kg
Metformin + swimming . -
pubmed
The current data emphasizes the need to individualize
DAPT duration at the
patient level to balance the clinical benefits of a reduced risk of cardiovascular
ischemic events with the greater risk of clinically significant
bleeding . -
pubmed
Patients at an increased risk of
ischemic events and a lower risk of
bleeding should be strongly considered for prolonged
DAPT beyond the 1 year currently recommended in the practice guidelines . -
pubmed
BACKGROUND :
Staphylococcus aureus is the major cause of global and
nosocomial infections with a significant impact in hospitals worldwide . -
pubmed
aureus isolates causing
infections in patients admitted to hospitals from Recife city , Brazil , and investigate the prevalence of
oxacillin - susceptible mecA - positive
S. - pubmed
Subjects were instructed to supplement the study drug with
hydrocodone /
acetaminophen liquid or
acetaminophen for
pain as needed . -
pubmed
Subjects in the placebo group required statistically significant ( P & lt ; .05 ) higher doses of narcotic and
acetaminophen to control
pain . -
pubmed
Overall , 41
patients died , 47 experienced
recurrence . -
pubmed
This paper reviews the most recent classification , pathophysiology and imaging findings in clinical research as well as the knowledge gained from studying genetic and lesional
animal models of
focal cortical dysplasia . -
pubmed
This review of this recently gained knowledge will most likely help develop new research models and new therapeutic targets for
patients with
epilepsy associated with
focal cortical dysplasia . -
pubmed
Methods Thirty - six
obese individuals , median age 44 ( 26 - 64 ) with median
body mass index at baseline of 42.5 ( 40.4 - 46 ) were studied before and 15 months after Roux - en - Y gastric bypass . -
pubmed
These findings suggest that choice of material is a patient and practitioner preference ; however , for
patients at risk of
hypoxia - related complications , SiHy materials should be considered . -
pubmed
Here , we synthesized this epitope as an octa - branched multiple antigenic peptide ( MAP ) to vaccinate
mice implanted with subcutaneous syngeneic colon (
CT26 ) , prostate (
TRAMP - C2 ) or renal ( RENCA ) cell line
carcinomas . -
pubmed
Mice with regressed
tumors demonstrated immune memory , preventing
tumor recurrence upon re - implantation ( p & lt ; 0.001 ) . -
pubmed
Study of genetic alterations , inherited or acquired , that increase the risk or drive
cancers and many other
diseases had remained mostly confined to coding sequences of the
human genome . -
pubmed
MATERIALS AND METHODS : Between January 2004 and January 2011 , 32
inpatients ( 18
male , 14
female ; age , 38 - 61 y ; mean , 48 y ) underwent ACDR for the treatment of
ASD after previous ACDF ( single - level : n=12 ; 2 - level : n=15 ; 3 - level : n=5 ) . -
pubmed
In 22
patients ,
ASD occurred above the fusion site , and in 10 it occurred below the site . -
pubmed
Before and after ACDR ,
patients were evaluated using the
pain visual analog scale ( VAS ) , the Japanese Orthopedic Association ( JOA ) score , and neck disability index ( NDI ) . -
pubmed
At the last follow - up , 2
patients had grade II
heterotopic ossification ; 3
patients had aggravated degeneration ( vs. preoperative status ) of the adjacent unfused segment . -
pubmed
In a partial thickness
burn injury model in
piglets , the drug - loaded mats displayed comparable
wound closure to commercially available
silver - based dressings . -
pubmed
OBJECTIVE : Needle - related procedures are the most common sources of
pain for
children in the hospital setting . -
pubmed
Natural Compound
Licochalcone B Induced Extrinsic and Intrinsic Apoptosis in
Human Skin
Melanoma (
A375 ) and Squamous Cell Carcinoma (
A431 ) Cells . -
pubmed
These results indicate that
Lico B has apoptotic effect on
A375 and
A431 skin cancer cells , suggesting the potential value of
Lico B for the treatment of
human melanoma and
SCC . -
pubmed
Pre- to postoperative coagulation profile of 307
patients undergoing oesophageal resection with epidural blockade over a 10 - year period in a single hospital : implications for the risk of
spinal haematoma . -
pubmed
Postoperative
thrombocytopenia was almost non - existent while aPTT or PT - INR was elevated above the reference range in 129/307
patients : aPTT was elevated in 116/307 while PT - INR was elevated in 32/307 . -
pubmed
BACKGROUND :
Peripheral neuritis caused by
acrylamide is well - known , and many Korean grouting
workers are frequently exposed to
acrylamide in grouting agents that are injected into cracked concrete . -
pubmed
We recently encountered two cases of
dermal and neural toxicity in Korean grouting
workers with exposure to grouting agents that contained a high concentration of
acrylamide . -
pubmed
The
patient developed peeling skin on both hands while grouting , which progressed to systemic neurological symptoms , such as
reduced sensory function and strength . -
pubmed
The
patient was diagnosed with
peripheral neuropathy caused by
acrylamide exposure , and fully recovered after conservative treatment and withdrawal of exposure to the grouting agent . -
pubmed
CONCLUSIONS : Both
workers had workplace
acrylamide exposure through dermal contact plus inhalation of dust and vapor , which led to the
neural toxicity and
dermatitis . -
pubmed
Tolerability of a rapid - escalation
vinblastine -
prednisolone protocol in
dogs with
mast cell tumours . -
pubmed
Dogs with chemotherapy - naive
MCTs presenting to the Oncology Service of a single institution were prospectively enrolled to receive escalating
vinblastine , and haematology and a standardised quality - of - life questionnaire were assessed prior to each dosage . -
pubmed
A total of 70 % of
dogs tolerated 3.00 mg / m2 given 7 days apart at day 14 and 21 , although 29 % of
dogs developed dose - limiting
toxicities and 8 % discontinued the protocol due to
toxicity . -
pubmed
Glucocorticoid mediates prenatal
caffeine exposure - induced
endochondral ossification retardation and its molecular mechanism in female fetal
rats . -
pubmed
Our previous studies discovered that prenatal
caffeine exposure (
PCE ) could induce
intrauterine growth retardation (
IUGR ) and
long - bone dysplasia in offspring
rats , accompanied by maternal glucocorticoid over - exposure . -
pubmed
This study is to explore whether intrauterine high glucocorticoid level can cause
endochondral ossification retardation and clarify its molecular mechanism in PCE fetal
rats . -
pubmed
The STELLA - LONG TERM study is an ongoing 3 - year post - marketing surveillance study of
ipragliflozin in
type 2 diabetes (
T2D )
patients . -
pubmed
RESEARCH DESIGN AND METHODS : All Japanese
patients with
T2D who were first prescribed
ipragliflozin between 17 July 2014 and 16 October 2015 at participating centers in Japan were registered in STELLA - LONG TERM . -
pubmed
CONCLUSIONS :
Ipragliflozin was well tolerated and effective in Japanese
patients with
T2D ; no new safety issues were identified . -
pubmed
Ertugliflozin and
Sitagliptin Co - initiation in
Patients with
Type 2 Diabetes : The VERTIS SITA Randomized Study . -
pubmed
This study assessed the efficacy and safety of co - initiation of
ertugliflozin and
sitagliptin compared with placebo in
patients with
T2DM inadequately controlled on diet and exercise . -
pubmed
CONCLUSION : Co - initiation of
ertugliflozin with
sitagliptin in
patients with
T2DM inadequately controlled on diet and exercise provided a clinically meaningful improvement in glycemic control over 26 weeks . -
pubmed
A
rat fracture study was conducted with 4 for 4 weeks to validate its utility in
bone fracture healing . -
pubmed
Studies suggest an increased frequency of
intestinal obstruction in
cerebral palsy patients . -
pubmed
We present a case of a 21 - year - old
man with severe
cerebral palsy and
kyphoscoliosis . -
pubmed
This autopsy highlights the need to maintain a high index of suspicion for small intestinal
volvulus in cases of
bowel obstruction in
cerebral palsy patients to expedite surgery and prevent mortality . -
pubmed
Early 7 - day supplemental parenteral nutrition improves body composition and muscle strength in
hypophagic cancer patients at nutritional risk . -
pubmed
Furthermore , EC showed antidiabetic effects such as improvement in
insulin resistance and the down - regulation of the blood
glucose level and liver lipid content in
type 2 diabetes model
mice . -
pubmed
Scavenging effect of oxidized biochar against the
phytotoxicity of lead ions on hydroponically grown
chicory : An anatomical and ultrastructural investigation . -
pubmed
To evaluate the scavenging effect of functionalized biochar against the
phytotoxicity of
Pb2 + , original biochar ( O - B ) was chemically oxidized with either
HNO3 or
KMnO4 to serve as biofilters (
O - BF ,
HNO3 - BF and
KMnO4 - BF ) to hydroponically grown
chicory (
Cichorium intybus L. var . - pubmed
Mycoplasma ovipneumoniae Associated with
Polymicrobial Pneumonia in a Free - Ranging Yearling Barren Ground Caribou (
Rangifer tarandus granti ) from Alaska , USA . -
pubmed
Mycoplasma ovipneumoniae has been reported in association with
respiratory disease in the wild only in members of the subfamily Caprinae of the family Bovidae . -
pubmed
ovipneumoniae in a cervid : a free - ranging barren ground caribou (
Rangifer tarandus granti ) yearling with
polymicrobial bronchopneumonia . -
pubmed
In this study , a novel
strain of
P. - pubmed
xyllostela ( Fuzhou - R2Ad ) with 120 - fold resistance to
Bt Cry2Ad was selected in the laboratory , after screening for 66 generations from the susceptible
strain Fuzhou - S. In the absence of
Bt Cry2Ad toxin , the Fuzhou - R2Ad had significantly lower fitness as compared to the susceptible
strain , which might be related to induced genetic changes to
Bt toxins . -
pubmed
Copper deficiency can change the microbiome of
swine . -
pubmed
As multiple inflamed plaques often co - exist in the coronary system ,
patients are at risk of repeated atherothrombotic cardiovascular events after
MI , with rates of 10 - 12 % at one year and 18 - 20 % at three years . -
pubmed
A chick - CAM model and
mouse model for
metastasis confirmed these results in vivo . -
pubmed
A randomized crossover trial of
elamipretide in
adults with primary
mitochondrial myopathy . -
pubmed
BACKGROUND : This study aims to evaluate the effect of subcutaneous ( SC )
elamipretide dosing on exercise performance using the 6 min walk test ( 6MWT ) ,
patient - reported outcomes measuring
fatigue , functional assessments , and safety to guide the development of the Phase 3 trial . -
pubmed
METHODS : MMPOWER-2 was a randomized , double - blind , placebo - controlled , crossover trial that enrolled
participants ( N = 30 ) with genetically confirmed primary
mitochondrial myopathy . -
pubmed
The results of this trial provided an efficacy signal and data to support the initiation of MMPOWER-3 , a 6 - month long , Phase 3 treatment trial in
patients with primary
mitochondrial myopathy . -
pubmed
METHODS : Initial ECG recordings of 41
patients with
ApHCM and 72
patients with
NSTEACS were analyzed retrospectively . -
pubmed
CONCLUSIONS : Compared with NSTEACS
patients , ApHCM
patients presented higher R and neg T wave voltage as well as a greater ST - segment
depression in the 12 - lead ECG . -
pubmed
The aim of this study is to evaluate feasibility and the dosimetric improvement of the OA workflow implemented in our institution for locally advanced
pancreatic cancer ( LAPC )
patients , in terms of target coverage and organs at risk ( OARs ) sparing . -
pubmed
METHODS : A retrospective cohort analysis was performed with 26
patients [ male / female 11/15 ; median age 68 ( range 45 - 83 ) years ] who underwent 3dLPD with stented pancreaticogastrostomy and superior mesenteric or portal vein resection for
pancreatic adenocarcinoma between November 2016 and June 2019 . -
pubmed
Postoperative complications occurred in 10 ( 38 % )
patients including severe complications ( Clavien - Dindo grade > 2 ) in 4 ( 15 % ) . -
pubmed
A polyphasic study was undertaken to establish the position of a Streptomyces
strain , isolate
PRKS01 - 65 T , recovered from sand dune soil collected at Parangkusumo , Yogyakarta Province , Java , Indonesia . -
pubmed
The
obese persons have larger foot length , width , higher peak pressure , and contact area . -
pubmed
These results indicate that there is considerable
asymptomatic infection with
SARS - CoV-2 within the healthcare workforce , despite current mitigation policies . -
pubmed
Modeling the load of
SARS - CoV-2 virus in
human expelled particles during
coughing and speaking . -
pubmed
Watermelon has been used to treat various ailments , such as
cardio - vascular diseases , aging related ailments ,
obesity ,
diabetes ,
ulcers , and various types of
cancers . -
pubmed
BACKGROUND : The purpose of the present study was to assess the radiographic incidence , location , and classification of
heterotopic ossification (
HO ) in
patients who underwent total ankle arthroplasty ( TAA ) with a 4th generation prostheses at a minimum of 1 - year follow up . -
pubmed
Heartbeat : increased use of NOACs in
patients with
atrial fibrillation reduces health care system costs by reducing
stroke incidence . -
pubmed
Rituximab as second - line therapy after new direct antiviral agents in
peripheral neuropathy Hepatitis C Virus related : always correct therapeutic approach ? -
pubmed
Steroid hormone actions in tissue culture cells and cell hybrids -- their relation to
human malignancies . -
pubmed
Myocardial metabolism of
cyclic 3,5 - adenosine monophosphate as influenced by
dipyridamole and
theophylline in
patients with
coronary heart disease . -
pubmed
The Eastern Cooperative Oncology Group has studied 187
patients with generalized progressive
malignant lymphoma classified as having the histologic sub - types histiocytic or mixed . -
pubmed
Prostaglandin E and F levels in
mouse epidermis are increased by
tumor - promoting
phorbol esters . -
pubmed
We present 2
patients with
congenital unialteral multicystic kidney disease with
hydropelvis . -
pubmed
Proceedings : Circulatory effects of the
prostaglandin E1 on spontaneously
hypertensive rats and normotensive
Wistar rats . -
pubmed
Summary -- A
patient with
follicular carcinoma , Hurthle cell type , who developed subglottic extension and uncontrollable
hemoptysis is presented . -
pubmed
Laryngectomy and thyroidectomy were eventually required to control
hemoptysis ; the
patient remains socially functional and asymptomatic after a 30 - month period . -
pubmed
The antistaphylococcal sera ( against 11 Oeding
strains of
S. - pubmed
The number in and distribution of Langerhans ' cells were studied in 11
patients with a
maculopapular drug eruption . -
pubmed
We used the Structured Interview for
DSM - III Personality Disorders to diagnose
DSM - III personality disorders systematically in 55
patients with
obsessive - compulsive disorder in the active - treatment cell of a controlled trial of
clomipramine hydrochloride . -
pubmed
Patients with a
cluster A personality disorder had significantly higher
obsessive - compulsive disorder severity scores at baseline , and the number of
personality disorders was strongly related to baseline severity of
obsessive - compulsive disorder symptoms . -
pubmed
The results of treatment of 72
patients with
ampullary choledocholithiasis ( 16 % of the total number of
patients with
choledocholithiasis ) are presented . -
pubmed
The results of clinical and x - ray investigations of 398
patients with disseminated
pulmonary lesions were analyzed . -
pubmed
When
rats are returned to a normoxic environment after chronic exposure to
hypoxia , they manifest a striking drinking response . -
pubmed
Thrombocytopenia was particularly severe in
patients with
bone marrow involvement . -
pubmed
When female
rats were given
chlordecone in addition to
estrogen plus
progesterone ,
chlordecone reduced the
lordosis behavior usually seen in these
steroid primed
animals . -
pubmed
To further examine the role that
substance P plays in initiating the observed massive postmortem bronchoconstriction in
guinea pig lungs and to explore the role of neural reflex in this
airway spasm , six groups of
animals were employed : control ( n = 6 ) ,
morphine ( n = 6 ) ,
substance P ( n = 5 ) , chronic
capsaicin pretreatment +
substance P ( n = 5 ) ,
tetrodotoxin (
TTX ) + acute
capsaicin ( n = 4 ) , and
chlorisondamine + acute
capsaicin ( n = 5 ) . -
pubmed
Quantitative radiographic scores for joint space narrowing erosion , and malalignment in the hands and wrists of 200
patients with
rheumatoid arthritis (
RA ) were significantly correlated with duration of disease . -
pubmed
Immunity patterns during
acute infection by
Eimeria bovis . -
pubmed
The
leukotrienes are putative major mediators of
human asthma . -
pubmed
Nodular granulomatous episclerokeratitis in
dogs : 19 cases ( 1973 - 1985 ) . -
pubmed
We examined the age and breed prevalence and the response to treatment of 19
dogs with
nodular granulomatous episclerokeratitis . -
pubmed
In these
dogs , this disorder was an idiopathic , bilateral disease characterized histologically by the presence of chronic
granulomatous inflammation and reticulin fiber formation . -
pubmed
The relationship between tourniquet pressures and
neurovascular injury in the
human digit is not clearly defined . -
pubmed
Reproductive isolation is induced by microorganisms in diverse geographic
strains of the flour beetle
Tribolium confusum ( Coleoptera : Tenebrionidae ) . -
pubmed
Infected
strains of
T. - pubmed
Ouabain - induced
hypertension in a
patient with decompensated
hypertensive heart disease . -
pubmed
Lymphoma susceptibility of the AKR
mouse strain acquired before the stage of implantation . -
pubmed
[ Radiosensitivity of
human malignant melanomas ] . -
pubmed
The relationship between
hepatocellular carcinoma ,
cirrhosis and
HB virus is briefly discussed in the light of these findings . -
pubmed
In some cases of
sudden infant death syndrome (
SIDS ) the intestinal flora was found to be dominated by
Candida albicans . -
pubmed
There is no basis to assume that the activity of yeasts , first of all of
Candida albicans , is a contributory factor in the occurrence of
SIDS . -
pubmed
Cerebrospinal fluid markers in relation to outcome in
patients with global
cerebral ischemia . -
pubmed
To investigate the possibility of improving the accuracy of prognostication in early
hypoxic brain damage , 12
patients with global
cerebral ischemia (
GCI ) due to
circulatory arrest outside hospital were followed until
death or for 1 yr . -
pubmed
A photogrammetric study of the depth of the central and peripheral anterior chamber of the iris was carried out in 37
subjects with the
pigment dispersion syndrome . -
pubmed
To test a convenient and reliable neuronal index that suggests the development of autonomous epileptogenicity , we conducted in acute experiments on
rabbits a comparative study of the changes in direct cortical responses ( DCRs ) in primary and mirror sites during electrically induced primary ( PRID ) and projected
seizure discharges ( PROD ) . -
pubmed
Electrograms were recorded from the His bundle area , right ventricular apex , right ventricular inflow tract , and left ventricular apical endocardium in four
patients ( aged , 1 , 1 , 1.5 , and 16 years ) with
Wolff - Parkinson - White syndrome type B. -
pubmed
[ Hoof
cyst (
keratoma ) in the
horse ] . -
pubmed
Long - term diuretic treatment of
patients with
congestive heart failure is often complicated by
hyponatremia and resistance to diuretic treatment , as well as by
hypokalemia . -
pubmed
Because
aldosteronism , such as accompanies the disease and diuretic treatment , increases intracellular
sodium , we have measured intracellular
sodium and
potassium in six
patients given a new
aldosterone antagonist (
canrenone ) . -
pubmed
Neurologic syndromes attributed to conditioning or medications have been reported in BMT
recipients . -
pubmed
A
patient is presented who developed
extrapyramidal symptoms on day +56 after allogeneic BMT . -
pubmed
Brain magnetic resonance images of this
patient demonstrated hyperintense basal ganglia , which has been associated with
manganese (
Mn )
toxicity . -
pubmed
The
patient had received total parenteral nutrition ( TPN ) with standard trace element supplementation and had been
cholestatic . -
pubmed
Cholestatic patients and those on long - term TPN have been found to have high blood or serum levels of
Mn , but generally are asymptomatic . -
pubmed
When other
cholestatic BMT
patients were reviewed , all had elevated serum
Mn . -
pubmed
Control of
pandemic infection of
human immunodeficiency virus type 1 (
HIV-1 ) requires some means of developing mucosal immunity against
HIV-1 because sexual transmission of the virus occurs mainly through the mucosal tissues . -
pubmed
Goose parvovirus is the etiological agent of
Derzsy ' s disease , a fatal
hepatitis of young geese . -
pubmed
The efficacy of short- and long - term treatments with
Isoprinosine , an immunomodulatory compound , was studied in
Echinococcus granulosus cysts developed in
NMRI mice intraperitoneally infected with
sheep pulmonary cysts . -
pubmed
PARTICIPANTS : A convenience sample of 368
patients presenting to the pediatric ED with
respiratory illnesses . -
pubmed
CONCLUSION : Clinical evaluation in a pediatric ED does not screen adequately for the detection of
hypoxemia and should be supplemented by routine
pulse oximetry in all
patients with respiratory findings . -
pubmed
[ The simultaneous evaluation of preoperative cardiopulmonary functions of
esophageal cancer patients in the analysis of expired gas with exercise testing ] . -
pubmed
Enrolled were 52 of
patients admitted between a period from 1991 to 1993 for thoracic
esophageal cancer , who underwent a radical operation of right thoracolaparotomy . -
pubmed
In order to evaluate the cytological homology of intermediate cells and melanocytes , and to investigate the function of melanocytes in the inner ear , hearing acuity and cochlear pathology were studied in three
strains of
mice , namely , wild type
mice ( + /+ ) , albino
mice without
melanin ( c2J / c2J ) , and
microphthalmia mice with no melanocytes ( mibw / mibw ) . -
pubmed
Our results suggest that : ( a ) acute
ethanol intoxication can induce direct contractions ( independent of
amine ,
prostanoid or opioid mediation ) of diverse
mammalian cerebral vascular tissues , including those from
primates ; ( b ) these contractile responses are heterogeneous along the cerebrovascular tree and independent of endothelial cells ; ( c ) in addition to a need for [
Ca2 +]o , an intracellular release of
Ca2 + is needed for
ethanol to induce contractions ; and ( d )
hypomagnesemia or
Mg deficiency potentiates the contractile effects of
ethanol on brain vessels and may be a risk factor for
ethanol - related ,
ischemic stroke events . -
pubmed
Form 1 was shared by five
rat strains from two vendors ; form 2 was shared by two
rat strains from the same vendor ; and forms 3 and 4 were unique to their vendor colonies . -
pubmed
These physiologic changes , along with increased
pain threshold , mimic the observed effects of
morphine and other mu - agonists in the
horse . -
pubmed
The results of this study suggest that endogenous opioid peptides may modulate
pain threshold as well as other physiologic parameters in the
horse . -
pubmed
Mechanisms involved in the pathogenesis of tubulointerstitial
fibrosis in 5/6 - nephrectomized
rats . -
pubmed
OBJECTIVE : There is a paucity of longitudinal endocrine studies of infertile
patients with
oligomenorrhoea . -
pubmed
PATIENTS : Infertile
women with
oligomenorrhoea (
PCOS , n = 131 ) presenting to the
infertility clinic at the Royal Infirmary , Glasgow . -
pubmed
The
animals were divided into three groups : control ,
acidosis , and
alkalosis . -
pubmed
In patients with
cystic fibrosis (
CF ) ,
respiratory tract infections caused by
Staphylococcus aureus and
Haemophilus influenzae are followed by
Pseudomonas aeruginosa with increasing age . -
pubmed
Chronic endobronchial lung infection with
P. - pubmed
In Danish
CF patients we noted that both onset of initial colonization and
chronic lung infection with
P. - pubmed
We established a
chronic P. aeruginosa lung infection in
rats by embedding mucoid bacteria in seaweed alginate and installing the beads intratracheally into the lower part of the left lung . -
pubmed
Although the
rats did not suffer from
CF , the antibody responses and the pathologic changes of the lungs mimicked the findings in
CF patients . -
pubmed
By using this model in normal and athymic
rats we showed that the T - cell response during the " natural " course of the
infection played no major role . -
pubmed
aeruginosa
pneumonia we found that the macroscopic inflammatory response of the lungs was immense and that the natural capacity to clear
P. - pubmed
In the chronic
rat model we succeeded to improve the survival significantly and to change the inflammatory response subsequent to vaccination from an
acute type inflammation dominated by polymorphonuclear leukocytes ( PMNs ) as in
CF patients to a
chronic type inflammation dominated by mononuclear leukocytes . -
pubmed
Furthermore , we found that
rats immunized with an alginate containing vaccine had a significantly earlier cellular shift to a
chronic type inflammation as well as a significant reduction in the severity of the macroscopic
inflammation compared to two other vaccine groups and to nonimmunized controls . -
pubmed
OBJECTIVES : To assess the incidence of isolated central nervous system ( CNS )
relapses in
patients of
acute lymphoblastic leukemia (
ALL ) treated with a protocol containing cranial irradiation and intrathecal
methotrexate as CNS directed therapy . -
pubmed
Retinal toxicity associated with
cisplatin and
etoposide in pediatric
patients . -
pubmed
Retinal toxicity is a side effect of the drug reported in
adults , but is not well described in pediatric
patients . -
pubmed
significantly , both
patients had
abnormal renal function . -
pubmed
We propose that the
patients at greatest risk of
cisplatin - induced
toxicity are those pretreated with
nephrotoxic therapy or those with
impairment of renal function from other causes . -
pubmed
In the case of a critical
flail chest with very serious physio - pathological consequences , if the
fractures are in technically favourable places , we think it is better to stabilize immediately , since the operating
trauma is minimum and in many cases the
patient is already intubated and curarized . -
pubmed
We report a detailed localization analysis of spontaneous magnetic brain activities in seven
BECRS patients using magnetoencephalography ( MEG ) . -
pubmed
All
patients had BECRS diagnosis with typical
seizures and electroencephalographic findings and five
patients had minor
psychomotor deficits . -
pubmed
Increased fast - wave activity was found in all five
patients with minor
neuropsychological deficits . -
pubmed
In
patients considered for bidirectional Glenn or Fontan procedures , the association of left superior vena cava ( LSVC ) with
ostial atresia of the coronary
sinus should be diagnosed preoperatively in order to avoid surgical division or ligation of the LSVC and the negative effect of resulting
coronary venous hypertension on myocardial perfusion . -
pubmed
Three
patients with the interval form of
carbon monoxide (
CO )
poisoning were studied for associations between their clinical courses and serial changes on : ( 1 ) MRI ; ( 2 ) EEG ; ( 3 ) single photon emission computed tomography with
N - isopropyl - p -[ 123I ] iodoamphetamine (
[ 123I ] IMP SPECT ) ; and ( 4 ) proton magnetic resonance spectroscopy ( [ 1HIMRS ) to evaluate their usefulness as prognostic predictors . -
pubmed
These results indicate that
[ 1H ] MRS is the most useful indicator in the clinical evaluation of
patients with the interval form of
CO poisoning . -
pubmed
Following
animal care committee approval , the effects of continuous infusions of
fluvoxamine and
sufentanil were studied in behavioural tests ( hot - plate test , tail - flick test ,
catalepsy test ) in
Sprague - Dawley rats with a jugular vein catheter . -
pubmed
No
animal showed
catalepsy . -
pubmed
Autoantigen - specific CD4+CD28low T cell subset prevents
autoimmune exocrinopathy in
murine Sjogren ' s syndrome . -
pubmed
Transfer of CD4+CD28low T cells into the
animal model actually prevented the development of
autoimmune lesions including autoantibody production . -
pubmed
These results suggest that a CD4+CD28low T cell subset that is continuously activated by an organ - specific autoantigen may play a regulatory role in the development of organ - specific
autoimmune disease in an
animal model of
SS . -
pubmed
Rehabilitation of
patients with severe ( Class VI )
maxillary resorption using Le Fort I osteotomy , interposed bone grafts and endosteal implants : 1 - 8 years follow - up on a two - stage procedure . -
pubmed
To study possible mechanisms responsible for the increased susceptibility to
infection of
patients with active
systemic lupus erythematosus (
SLE ) , a study of the serum heat - labile opsonic capacity ( HLOC ) in such patients was undertaken . -
pubmed
With leukocytes from normal donors , the sera of 12 of 30
patients with active
SLE demonstrated decreased HLOC for
E. - pubmed
While 8 of 10 patients with active
SLE and concomitant
infections showed deficient opsonic capacity to
E. - pubmed
In the
patients surviving
infection , recovery of normal serum opsonic capacity was rapid and usually coincided with an increase of serum complement to normal levels . -
pubmed
In three
patients with active
SLE and
infection , the causative microorganisms were isolated and opsonic capacity for these organisms tested with the individual
patients ' sera . -
pubmed
This defect may be an important factor in the increased susceptibility to
infections of
patients with active
systemic lupus erythematosus . -
pubmed
A case of a
patient with
fibrous dysplasia of craniofacial bones associated with
primary hyperparathyroidism without additional
endocrinophaties or associated disorders , will be presented . -
pubmed
In the present study , our results suggest that
Caffeine inhibits solid
tumour development and pulmonary experimental
metastasis induced by
B16F10 melanoma cells , in
murine model . -
pubmed
Odontoclastic resorptive lesion of a
mandibular right first molar in a
cougar . -
pubmed
Helicobacter pylori seropositivity in patients with
hyperemesis gravidarum . -
pubmed
METHODS : From November 1999 to February 2001 , we enrolled 54 pregnant
women with
hyperemesis gravidarum and 53 asymptomatic pregnant
women in a prospective study . -
pubmed
RESULTS : Serologically positive
Helicobacter pylori infection was detected in 44 out of 54 patients with
hyperemesis gravidarum ( 81.5 % ) whereas 29 out of 53 asymptomatic gravidas ( 54.7 % ) had positive antibody titers for
Helicobacter pylori . -
pubmed
The ratio of
Helicobacter pylori seropositivity in pregnant
women with
hyperemesis gravidarum was significantly higher than asymptomatic pregnant women ( P<0.01 ) . -
pubmed
CONCLUSIONS : There is a significant association between
Helicobacter pylori infection and
hyperemesis gravidarum in our hyperemetic pregnant
patients . -
pubmed
[ Assessment of variables relative to prethrombotic state after operation in
patients with
gynecological malignancies ] . -
pubmed
OBJECTIVE : To study the changes in the variables in
patients with
gynecological malignancies after operation . -
pubmed
CONCLUSIONS : Obvious prethrombotic state characterizes the
patients with
gynecological malignancies after operation . -
pubmed
We studied radiographs of 125
children ( 105
boys , 20
girls ) with unilateral
Legg - Calve - Perthes ' disease to examine the epiphyseal development of the femoral head in the contralateral ( unaffected ) hip . -
pubmed
Mice of the C57BL
strain are highly resistant to the oncogenic property of LID-1
polyoma virus , but complete thymectomy within 24 hours of birth rendered these
mice susceptible . -
pubmed
In thymectomized
mice inoculated with adult syngeneic spleen cells , the capacity to resist
oncogenesis was restored . -
pubmed
The results add further weight to the concept that induction and progression of
tumors by
polyoma virus has an immunologic basis . -
pubmed
We compared two groups of
patients : group A--13
patients studied 3 months after operation ; and group B--25
patients studied at a median of 4 years after operation ( range 2 - 8 years ) without
coronary occlusive disease (
COD ) . -
pubmed
The onset time , rate of rise , and duration of changes in the excitability of corticospinal projections to the agonist muscle were normal in the
patients with
dystonia . -
pubmed
Muscle activity in antagonist and proximal muscles of the upper arm was reduced significantly in the
dystonia patients . -
pubmed
These findings support the view that movement preparation and initiation at the level of the primary motor cortex is normal in
patients with
dystonia . -
pubmed
Helicobacter pylori causes
chronic gastritis worldwide and it is the most important single factor in
peptic ulcer disease . -
pubmed
pylori infection has also been classified as a class I carcinogen in
human gastric cancer . -
pubmed
Relation of ECG changes to neurological outcome in
patients with
aneurysmal subarachnoid hemorrhage . -
pubmed
METHODS : All
patients admitted to a 31 - bed department of intensive care between 1993 and 2000 with acute
aneurysmal SAH documented by cerebral angiography or autopsy were included . -
pubmed
RESULTS : Of 159
patients ( 49.6 years [ range : 20 - 75 ] ) with acute
SAH , 106 ( 66.7 % ) had abnormal ECGs ( classified by an observer blinded to the
patients ' clinical course and outcome . -
pubmed
CONCLUSIONS : In
patients with acute aneurysmal
SAH , repolarization abnormalities are the commonest ECG alterations , and ST
depression is more common in
patients with poor outcome . -
pubmed
Fifteen
patients with advanced
colorectal cancer refractory to standard chemotherapies consumed capsules compatible with
curcumin doses between 0.45 and 3.6 g daily for up to 4 months . -
pubmed
The authors report a case of primary
cardiac angiosarcoma of the right atrium with
pulmonary , hepatic , cerebellar and bony metastases in a 46 - year - old
man who clinically presented as
pulmonary hemorrhage . -
pubmed
Information is limited regarding the histological features related to
chronic graft dysfunction and failure in
patients with
IgA nephropathy developing after renal transplantation . -
pubmed
In conclusion , the current study suggests that glomerular crescents are not rare and that they are responsible for
chronic graft dysfunction in
TxIgAN patients . -
pubmed
Streptococcal necrotising fasciitis from diverse
strains of
Streptococcus pyogenes in tropical northern Australia : case series and comparison with the literature . -
pubmed
Therefore , in the present study ITT was performed in healthy adults ( n = 21 ) , adult
patients with
monaural central perforation ( n = 31 ) or strong
scar formations ( n = 24 ) of the tympanic membrane and 18 adult
patients after monaural canal wall down surgery . -
pubmed
In healthy adults ( 36.50 degrees C vs. 36.51 degrees C )
patients with monaural central perforation of the tympanic membrane ( 36.41 degrees C vs. 36.34 degrees C ) and with monaural strong
scar formations in the tympanic membrane ( 36.39 degrees C vs. 36.45 degrees C ) , no significant difference between the right and left ear could be proved . -
pubmed
Brain tissue fragments in the amniotic fluid of
rats with
neural tube defect . -
pubmed
We looked for brain tissue fragments in amniotic fluid of
rats with
NTD as it is the basis for the aspiration hypothesis . -
pubmed
Experimental
rats received 100,000 U of
vitamin A in 1 mL of
corn oil on gestational days 8 , 9 and 10 , while control
rats received
corn oil . -
pubmed
A
mucosal disease - like condition in
lambs with
hairy shaker disease . -
pubmed
Previously we reported that an ordinarily nonlethal dose of
thioacetamide ( 300 mg / kg ) causes
liver failure and 90 % mortality in
type 1 diabetic rats , primarily because of inhibited tissue repair . -
pubmed
On the other hand , the
diabetic rats receiving 30 mg
thioacetamide / kg exhibited equal initial
liver injury and delayed tissue repair compared to nondiabetic
rats receiving 300 mg
thioacetamide / kg , resulting in a delay in recovery from that
liver injury and survival . -
pubmed
The aim of this longitudinal investigation was to evaluate the clinical response to scaling and root planing combined with the use of locally delivered
minocycline microspheres for 720 days in
individuals with advanced
chronic periodontitis . -
pubmed
UNLABELLED : We investigated the clinical feature of
thoracic injury patients , mainly with
diaphragmatic injury . -
pubmed
From 1993 to 2005 , 739
patients with
thoracic injury were treated at our life - saving emergency center . -
pubmed
There were more blunt
trauma patients than
penetrating injury patients ( 693 cases vs 46 cases ) . -
pubmed
In addition , thoracoscopy is very useful for both examining and treating traumatic
diaphragmatic injury patients . -
pubmed
Bovine transcriptome analysis by SAGE technology during an experimental
Trypanosoma congolense infection . -
pubmed
However , several indigenous West African
taurine breeds (
Bos taurus ) present remarkable tolerance to the
infection . -
pubmed
Human aging is characterized by skeletal
muscle wasting , a debilitating condition which sets the susceptibility for diseases that directly affect the quality of life and often limit life span . -
pubmed
The identification of the molecular chain able to reverse
sarcopenia is a major goal of studies on
human aging . -
pubmed
RESULTS : In total , 72 proteins were identified and quantified in the comparison of pancreatic juice from
pancreatitis patients versus pooled normal control juice . -
pubmed
OBJECTIVE : A series of published cases show that repair of
brachial plexus injuries by reimplantation of avulsed spinal roots can restore a degree of recovery , particularly to the more proximal shoulder and arm musculature in a proportion of
patients . -
pubmed
METHODS : This study was based on our previous
rat model showing regeneration of severed fibers and resumption of function after transplantation of cultured adult olfactory ensheathing cells into
spinal cord injuries and reimplanted dorsal roots . -
pubmed
BACKGROUND AND OBJECTIVES : To study the effect of 0.2 mg mL-1 of
ondansetron added to
morphine patient - controlled analgesia solution after a 4 mg loading dose on the incidence and severity of
postoperative nausea and vomiting . -
pubmed
Patients who smoked , received antiemetics and hormonal therapy , had a history of
motion sickness or
gastrointestinal disease , a
body mass index & gt;35 or menstruation at the time of the study were excluded . -
pubmed
The
nausea score ,
vomiting score and the requested
ondansetron dose were evaluated at 1 , 2 , 6 , 12 and 24 h.
Patient - satisfaction for
nausea /
vomiting was recorded at the end of the study . -
pubmed
RESULTS :
Patient characteristics and cumulative
morphine consumption were similar but
ondansetron group had higher
pain scores ( P = 0.006 ) . -
pubmed
The
ondansetron group had a lower
nausea and
vomiting scores , and more
patients were free from
nausea and
vomiting than the control group ( 41 vs. 26 , respectively , P = 0.025 ) . -
pubmed
CONCLUSION(S ):
Ondansetron 4 mg plus 0.2 mg mL-1 given with
PCA morphine can reduce
nausea and
vomiting thus improving
patient satisfaction . -
pubmed
We studied the effects of consuming 15 % of the daily caloric intake in the form of
pistachio nuts on the lipid profiles of free - living
human subjects with primary , moderate
hypercholesterolemia ( serum
cholesterol greater than 210 mg / dL ) . -
pubmed
subjects : 15
subjects with moderate
hypercholesterolemia . -
pubmed
CONCLUSION : A diet consisting of 15 % of calories as
pistachio nuts ( about 2 - 3 ounces per day ) over a four week period can favorably improve some lipid profiles in subjects with moderate
hypercholesterolemia and may reduce risk of
coronary disease . -
pubmed
METHODS : Thirty
obese adults ( mean
body mass index 29 - 30 kg / m(2 ) ) were randomized to two groups . -
pubmed
Subjective visual horizontal in
patients with
posterior canal benign paroxysmal positional vertigo . -
pubmed
CONCLUSION :
Patients with
posterior canal benign paroxysmal positional vertigo ( p -
BPPV ) could have mild excitation in the vestibular system on the affected side . -
pubmed
While subjective visual horizontal ( SVH ) mainly reflects utricular function , there is less documentation on
SVH in
patients with
p - BPPV . -
pubmed
PATIENTS AND METHODS : Twenty - eight
patients with unilateral idiopathic p -
BPPV were enrolled . -
pubmed
For comparison , 17
patients with
vestibular neuritis and 45
patients with
cerebello - pontine angle ( CPA )
tumor were also examined . -
pubmed
Conversely , deviation of
SVH was toward the affected side down in 88.2 % of
patients with
vestibular neuritis and in 75.6 % of
patients with CPA
tumor . -
pubmed
PATIENTS AND METHODS : A questionnaire identified
pain level in a cohort of
patients that had previously undergone corrective groin
hernia surgery . -
pubmed
RESULTS : Thirty - two
patients were evaluated for response rate ( RR ) and
skin toxicity to establish the best management . -
pubmed
Of 34
patients evaluable for
cutaneous toxicity , 10
patients ( 29 % ) presented with grade 1 eruption , 13 ( 38 % ) with grade 2 eruption , and 4 ( 12 % ) with grade 3 eruption . -
pubmed
Allergic reactions such as
flushing and
urticaria ( grade 2 ) were seen in 2
patients ( 6 % ) . -
pubmed
The patient was a 36 - year - old
man with
polyarthralgia ,
fatigue and
swelling of his upper eyelids and all four limbs . -
pubmed
We present our experience with computed tomographic angiography in 3 pediatric
patients with
vascular injuries secondary to
blunt trauma . -
pubmed
SUMMARY : Among gram - positive
bacterial infections , differentiating between healthcare - associated and community - associated
methicillin - resistant
Staphylococcus aureus infections is becoming more difficult and can seriously impact therapeutic strategies and hence outcomes . -
pubmed
Early bronchodilatory effects of
budesonide /
formoterol pMDI compared with
fluticasone /
salmeterol DPI and
albuterol pMDI : 2 randomized controlled trials in
adults with persistent
asthma previously treated with inhaled
corticosteroids . -
pubmed
Two identically designed , randomized , multicenter , single - dose , crossover studies were conducted in
patients aged & gt ; or = 18 years with mild to moderate
asthma previously treated with inhaled
corticosteroids . -
pubmed
This study reviews 40
patients with primary isolated
arthritis of the medial compartment of the knee that underwent unicompartmental knee arthroplasty through a minimally invasive approach . -
pubmed
Preclinical studies showed the ability of the drugs to reverse
hyperglycaemia in diabetic
non - obese diabetic ( NOD ) mice providing rationale for clinical trials with the agents . -
pubmed
The former two drugs have been tested in
subjects with new onset
type 1 diabetes . -
pubmed
The assessment of cerebral autoregulation is a key to the optimisation of cerebral perfusion pressure in
patients with
brain injury . -
pubmed
Rare cases of
inflammatory pseudotumor (
IPT ) in two
adolescents are reported . -
pubmed
These two cases are reported to emphasize IPT of the liver as a differential diagnosis of
hepatic masses in
children because recognition of this condition before operation can avoid unnecessary surgery . -
pubmed
In
honeybee (
Apis mellifera ) societies , the queen controls the development and the caste status of the members of the
hive . -
pubmed
We describe the cases of two men , one of whom was a non - alcoholic 50 - year - old
man who had been on hunger strike for 50 days and who was admitted to hospital with
dysarthria ,
unstable gait ,
disorientation ,
ophthalmoplegia and
ataxia . -
pubmed
In both
patients , magnetic resonance imaging showed bilateral and symmetrical
injuries around Silvio 's aqueduct and in the periventricular region of both thalami . -
pubmed
Patients with
phlebolymphedema have skin changes of
venous insufficiency , which are easy to recognize . -
pubmed
VARIATIONS IN
CO ( 2 ) REQUIREMENTS AMONG BOVINE
STRAINS OF
BACILLUS ABORTUS . -
pubmed
Strains of
Bacillus abortus freshly isolated vary in their
CO ( 2 ) requirements . -
pubmed
A young
woman with
renal colic presenting with
urogenital anomaly : a case report . -
pubmed
CONCLUSION : Understanding the predictors of early treatment discontinuation in the care of
schizophrenia patients is important for the development of interventions to improve treatment outcome . -
pubmed
Anesthesia with the ProSeal Laryngeal Mask Airway for a
patient with
Mounier - Kuhn syndrome . -
pubmed
BACKGROUND :
Patients with
osteoarthritis of the hip demonstrate a limp while ambulating , and persistent asymmetric limb loading following unilateral total hip arthroplasty might induce further complications in the affected and contralateral limbs . -
pubmed
During the past 50 years , a variety of bone - seeking radiopharmaceuticals have been developed and evaluated to detect skeletal
metastases by imaging ( 1 - 3 ) or as
pain palliative agents in
patients ( 4 ) . -
pubmed
Two novel Gram - reaction - positive , rod - shaped actinobacterial
strains , designated
RP - B26(T ) and
RP - B30(T ) , were isolated from rhizosphere soil of a cliff - associated plant (
Peucedanum japonicum Thunb . ) -
pubmed
The DNA G+C contents of
strains RP - B26(T ) and
RP - B30(T ) were 73.0 and 71.7 mol% , respectively . -
pubmed
Levels of DNA - DNA relatedness between the isolates were 44.9 + - 1.5 % ( thermal renaturation method ) and 43.2 % (
photobiotin - labelled method ) ; the isolates showed low DNA - DNA relatedness values ( & lt;11 % ) to the most closely related
strain ,
N. - pubmed
( type
strain RP - B26(T ) = KCTC 19368(T ) = DSM 19768(T ) ) and
Nocardioides maradonensis sp . - pubmed
( type
strain RP - B30(T ) = KCTC 19384(T ) = DSM 19769(T ) ) are proposed . -
pubmed
BACKGROUND : A perforating phenotype is associated with an increased postoperative morbidity in
patients with
Crohn ' s disease undergoing ileocolic resection . -
pubmed
METHODS : In all , 197
patients underwent 231 bowel resections for perforating
ileitis between 1992 and 2009 . -
pubmed
Patients with symptoms lasting & gt;5 months prior to surgery had a higher incidence of postoperative
septic complications ( 31 % versus 13 % , P = 0.002 ) , both by univariate and multivariate analysis . -
pubmed
CONCLUSIONS : Delay of surgery in
patients presenting with symptoms attributable to
perforating ileitis is associated with an increased postoperative risk . -
pubmed
Impact of
positive surgical margins on prostate - specific antigen failure after radical prostatectomy in adjuvant treatment - naive
patients . -
pubmed
Despite excellent surgical
cancer control , up to 40 % of
patients will have biochemical
recurrence following radical prostatectomy ( RP ) for localized
prostate cancer . -
pubmed
However , decision of further management ( adjuvant or salvage therapy ) in
patients with
PSM remains controversial , and many debatable questions arise concerning the incidence of clinical progression and the impact of systematic adjuvant treatment on the
cancer specific and overall survival . -
pubmed
METHODS : A total of seven
patients with nine
adrenal metastases treated with SBRT at the University of Pittsburgh Cancer Institute were retrospectively studied . -
pubmed
Follow - up imaging for six
patients , and eight metastatic
lesions , revealed one complete response , two partial responses and five stable lesions . -
pubmed
[ Diagnostic approach to
Streptococcus bovis bacteremia , or the limits of the evidence - based medicine ] . -
pubmed
Genetically inbred Balb / c
mice differ from outbred Swiss Webster
mice on discrete measures of sociability : relevance to a genetic
mouse model of
autism spectrum disorders . -
pubmed
Moreover , because
impaired sociability may influence the social behavior of stimulus
mice , we also measured the proportion of total episodes of social approach made by the stimulus
mouse while test and stimulus
mice were allowed to interact freely . -
pubmed
The data support previous reports that the Balb / c
mouse is a genetic
mouse model of
impaired sociability . -
pubmed
The data also show that the behavior of the social stimulus
mouse is influenced by the impaired sociability of the Balb / c
strain . -
pubmed
Interestingly , operationally defined measures of sociability did not necessarily correlate with each other within
mouse strain and the profile of correlated measures differed between
strains . -
pubmed
rearing , grooming and wall climbing ) recorded during the session of free interaction between the test and social stimulus
mice were more intensely displayed by Swiss Webster than Balb / c
mice , suggesting that the domains of sociability and " restricted repetitive and stereotyped patterns of behavior " are independent of each other in the Balb / c
strain . -
pubmed
AIMS : Peak
oxygen uptake ( VO(2 ) ) is diminished in
patients with
heart failure with preserved ejection fraction (
HFpEF ) suggesting impaired cardiac reserve . -
pubmed
To test this hypothesis , we assessed the haemodynamic response to exercise in
HFpEF patients . -
pubmed
METHODS AND RESULTS : Eleven
HFpEF patients ( 73 + - 7 years , 7
females/4
males ) and 13 healthy controls ( 70 + - 4 years , 6
females/7
males ) were studied during submaximal and maximal exercise . -
pubmed
The DeltaQ(c)/DeltaVO(2 ) slope was abnormally elevated in
HFpEF patients vs. controls ( 11.2 + -3.6 vs. 8.3 + - 1.5 ; P = 0.015 ) . -
pubmed
CONCLUSION : Contrary to our hypothesis , cardiac reserve is not significantly impaired in well - compensated
outpatients with
HFpEF . -
pubmed
Future treatment of
patients with
HCV cirrhosis . -
pubmed
Of all
hepatitis C virus (
HCV ) patients , those with
cirrhosis are most in need of treatment because of increased morbidity and mortality . -
pubmed
However , the sustained virological response ( SVR ) is lower in
patients with
cirrhosis . -
pubmed
In naive
patients , the SVR rate with the triple regimen with
boceprevir was increased by 14 % in
patients with severe
fibrosis or
cirrhosis compared with PR . -
pubmed
PSI risk - adjusted rate increased linearly by severity of
patient indication : claudicants ( OR = 0.40 ; 95 % CI , 0.35 - 0.46 ) ,
rest pain patients ( OR = 0.78 ; 95 % CI , 0.69 - 0.90 ) ,
ulcer ( OR = 1.20 ; 95 % CI , 1.07 - 1.34 ) , and
gangrene patients ( OR = 1.85 ; 95 % CI , 1.66 - 2.06 ) . -
pubmed
CONCLUSIONS :
Patient safety events in vascular surgery were high and varied by procedure , with amputations and open
abdominal aortic aneurysm repair having considerably more potential adverse events . -
pubmed
The
Azacitidine is actually authorised for the treatment of
CMML patients with 10 - 29 % marrow blasts without
myeloproliferative disorder , who are not eligible for haematopoietic stem cell transplantation . -
pubmed
Here we report a case of an atypical delayed and prolonged
hematologic toxicity during
Azacitidine treatment in a
CMML patient ; furthermore we also reviewed the literature regarding the efficacy of the drug and the management of hematologic adverse effects , in term of dose adjustments or alternative schedule of administration , in specific
CMML setting . -
pubmed
A total of 157
children ages 10 to 18 and their parents enrolled in a pediatric
pain rehabilitation program completed the
Pain Stages of Change Questionnaire ( PSOCQ youth and parent versions ) at pretreatment , posttreatment , and short - term follow - up . -
pubmed
Collagen sponge scaffolds containing 2,000 - 30,000 hVSEL cells were implanted into
cranial defects generated in
SCID mice . -
pubmed
Most of the studies included
patients with
prostate cancer . -
pubmed
METHODS :
Women with measurable recurrent or persistent
endometrial cancer and documented
disease progression were treated with
ridaforolimus 12.5 mg intravenously once daily for 5 consecutive days every 2 weeks in a 4 - week cycle . -
pubmed
CONCLUSION : Single - agent
ridaforolimus has antitumor activity and acceptable tolerability in advanced
endometrial cancer patients . -
pubmed
BACKGROUND :
Osteoarthritis (
OA ) is a frustrating disease for both
patient and physician because neither cause nor cure is known and there are currently no disease - modifying drugs . -
pubmed
METHODS : After reviewing
disease progression in
human OA , as demonstrated by histological analyses , the reasons for
cartilage erosion are explored and possible therapeutic approaches are highlighted . -
pubmed
Odds of starting a race and of earning money racing were lower for
horses with any lesion and lower for
horses with proximal phalangeal dorsoproximal articular margin chip
fracture , proximal sesamoid
bone fracture or
sesamoiditis , or wedge - shaped central or third tarsal bones , compared with horses that had no lesion . -
pubmed
For
horses that raced , proximal phalangeal dorsoproximal articular margin chip
fractures were associated with lower lifetime earnings , and flattening of the medial femoral condyle was associated with fewer 3 - year - old racing starts , compared with values for
horses that had no lesion . -
pubmed
In
CNE2 and
HONE1 nude mice xenograft models , orally
NVP - BEZ235 efficiently attenuated
tumor growth with no obvious toxicity . -
pubmed
Based on the above results ,
NVP - BEZ235 , which has entered phase I / II clinical trials in
patients with advanced
solid tumors , has a potential as a monotherapy or in combination with
CDDP for NPC treatment . -
pubmed
The protective effects of volatile anesthestics against the bronchoconstriction induced by an
allergic reaction in sensitized
rabbit pups . -
pubmed
Inhalation of volatile anesthetics , particularly
sevoflurane , promotes an earlier easing of the
bronchospasm ; this beneficial profile may be advantageous in
children with
atopic lung diseases . -
pubmed
In
human sepsis , there is new interest in glucocorticoid therapy at a physiological dose after reports of improved response to vasopressor drugs and decreased mortality in a selected group of
patients . -
pubmed
Nine
patients with
septic shock and nine healthy controls were prospectively enrolled . -
pubmed
Mononuclear cells and serum samples were obtained from the
patients with
sepsis on admission to the Intensive Care Unit and on the day of discharge from hospital , and from healthy
volunteers matched by age and sex with the
patients . -
pubmed
Glucocorticoid sensitivity was studied in control mononuclear cells cultured in the presence of serum from normal or
septic patients . -
pubmed
In addition , it performed much better in
acute toxicity tests and via oral administration in
mice than
cyclosporin A (
CsA ) , with few adverse reactions and low
toxicity in experimental animals . -
pubmed
Oral administration of
isogarcinol in
mice resulted in a dose - dependent decrease in
delayed type hypersensitivity ( DTH ) and prolonged graft survival in allogeneic skin transplantation . -
pubmed
METHODS : In this clinical trial , 56 cases of
acne patients with
yin - deficiency - inner heat type were enrolled . -
pubmed
The therapeutic effect was evaluated by
skin lesion score and
patients ' constitution score . -
pubmed
RESULTS : Of the
patients in the moxibustion and control groups , 2 and 1 was cured ( the
acne subsided above 90 % and symptoms disappeared ) , 14 and 6 experienced marked improvement ( the
acne subsided by 60%-90 % and symptoms were obviously relieved ) , 10 and 15 were effective ( the
acne subsided by 30%-59 % and symptoms were relieved ) , 3 and 5 invalid ( the
acne subsided by below 30 % and symptoms were worsen ) , respectively . -
pubmed
CONCLUSION : Suspended moxibustion is effective in improving both
skin lesion and
yin - deficiency constitution in
acne patients with
yin - deficiency - inner heat type . -
pubmed
Our objective was to examine the effect of nanoparticulate
paclitaxel on
prostate cancer cells derived from castration - resistant
prostate cancer in
men and
dogs , as companion
dogs represent a unique naturally occurring model of castration - resistant
prostate cancer . -
pubmed
RESULTS : Nanoparticulate
paclitaxel was as effective as standard
paclitaxel in decreasing cell viability , decreasing colony forming ability , and inducing apoptosis in
human and
canine prostate cancer cells in a dose - dependent manner . -
pubmed
CONCLUSIONS : Nanoparticulate
paclitaxel is as effective as
paclitaxel in decreasing cell viability , initiating apoptosis , decreasing cell survival , and causing rigidity of microtubules in both
human and
canine castration - resistant
prostate cancer . -
pubmed
Therefore , this study was conducted to evaluate the medium - term effects of LAGB on
weight loss and metabolic outcomes of obese
patients with different
body mass index (
BMI ) in China . -
pubmed
The
patients were evaluated at years 1 , 3 , and 5 after operation in the outpatient clinic , and the
weight loss , metabolic parameters , and remission of comorbidities were measured . -
pubmed
CONCLUSIONS : Relatively low medium - term
weight loss , metabolic improvement , and resolution or remission of
obesity - related comorbidities and high reoperation rate were observed in our population of
patients with
BMI & gt;= 35 kg / m2 who underwent LAGB . -
pubmed
Serotonin and
sudden death : differential effects of serotonergic drugs on
seizure - induced
respiratory arrest in DBA/1
mice . -
pubmed
In the DBA/1
mouse model of
sudden unexpected death in
epilepsy (
SUDEP ) , administration of a selective
serotonin ( 5 - HT ) reuptake inhibitor ( SSRI ) ,
fluvoxamine , completely suppressed
seizure - induced
respiratory arrest ( S - IRA ) at 30 min after administration ( i.p . ) -
pubmed
Serotonergic antagonists may be problematic in
patients with
epilepsy . -
pubmed
Cytotoxicity of
TiO2 nanoparticles to
mussel hemocytes and gill cells in vitro : Influence of synthesis method , crystalline structure , size and additive . -
pubmed
A 57 - year - old
man presented to the authors ' department with
pain over the right hip joint over a 3 - month period . -
pubmed
Microbiologic examination showed a
Staphylococcus aureus strain . -
pubmed
The aim of this study was to determine if SUA levels are associated with nutritional risk and consequently with adverse clinical outcomes in
MHD patients . -
pubmed
The effect of re - operation on survival in
patients with recurrent
glioblastoma . -
pubmed
PATIENTS AND METHODS : A retrospective analysis was performed for
GBM patients followed between 01/2005 and 06/2010 at our Institution . -
pubmed
RESULTS : Two hundred and thirty - two
patients with recurrent
GBM were evaluated . -
pubmed
CONCLUSION : Second surgery might have a limited impact in the clinical course of recurrent
GBM patients . -
pubmed
Although
otitis media is extremely frequent in
children ,
tympanogenic labyrinthitis is not commonly observed , which suggests the existence of a potent anti - inflammatory mechanism modulating
cochlear inflammation . -
pubmed
This surgical approach enables rapid and direct delivery into the scala tympani while minimizing
blood loss and avoiding
animal mortality . -
pubmed
Lymph node and spleen cells of
mice doubly immunized by epicutaneous and intravenous hapten application produce a suppressive component that inhibits the action of the effector T cells that mediate
contact sensitivity reactions . -
pubmed
Quantitative PCR analyses of DNA from liver tissue , ocular , oral , nasal , and cloacal swabs were all positive for ranavirus , and sequencing of the template confirmed
infection with a
FV3 - like ranavirus . -
pubmed
This is the first report of morbidity and mortality of a
mud turtle with a
systemic ranaviral infection . -
pubmed
Staphylococcus aureus is a leading cause of
skin and soft tissue infections ,
foreign body infections , and
infective endocarditis . -
pubmed
In case of endovascular
infection with
S. - pubmed
Infections caused by
Staphylococcus aureus strains with
Methicillin resistance are associated with increased mortality and morbidity , aggressive course , multiple drug resistance and hospital outbreaks . -
pubmed
We report a case of multiple
hereditary exostosis in a 33 - year old
patient with clinical symptoms of
pain and impression of a growing mass of the left shoulder alerting potential risk of malignant transformation of an
osteochondroma . -
pubmed
A low serum
Mg level on admission ( HMg0 ) has been associated with more severe presentation in
patients with
subarachnoid hemorrhage . -
pubmed
We sought to determine the incidence and clinical significance of HMg0 in
patients with
ICH . -
pubmed
METHODS : We reviewed the records of consecutive
patients with
ICH over a 2 - year period . -
pubmed
CONCLUSIONS : HMg0 occurs in one third of
patients with
ICH and is associated with more severe presentation and
intraventricular hemorrhage . -
pubmed
We recorded blood pressure ( BP ) and bilateral middle cerebral artery flow velocity ( MCAv ) in a cohort of
TIA patients ( n = 17 ) , and age - matched controls ( n = 15 ) . -
pubmed
BPV attenuation may be an important therapeutic strategy for enhancing secondary
stroke prevention in
patients who suffer a
TIA . -
pubmed
Cognitive training has been shown to result in improved behavioral performance in normal aging and
mild cognitive impairment (
MCI ) , yet little is known about the neural correlates of cognitive plasticity , or about
individual differences in responsiveness to cognitive training . -
pubmed
In this study , 21 healthy older
adults and 14
patients with
MCI received five weeks of adaptive computerized working - memory ( WM ) training . -
pubmed
Although
MCI patients showed improved behavioral performance at low WM load after training , no evidence was found for training - related changes in prefrontal activation . -
pubmed
To compare physiological and photochemical competency , the pigment composition of discrete life cycle stages was determined for the common resting
cyst - producing dinoflagellate
Scrippsiella lachrymosa . -
pubmed
Original Research : Diametric effects of
hypoxia on pathophysiology of
sickle cell disease in a
murine model . -
pubmed
We report that
hypoxia rapidly decreased
oxygen saturation in
transgenic sickle cell disease mice , but this effect was immediately buffered by a robust ventilatory response . -
pubmed
Synergistic and attenuated effect of HSS in combination treatment with
docetaxel plus
cisplatin in
human non - small - cell lung
SPC - A-1 tumor xenograft . -
pubmed
Many reports indicated that
patients with
tumors can benefit from adjuvant chemotherapy drugs . -
pubmed
PATIENTS AND METHODS : A 49 - year - old
man presented a
rash on the seventh day of treatment with
esomeprazole ,
clarithromycin and
amoxicillin prescribed for
gastritis involving
Helicobacter pylori . -
pubmed
Cardiac glycosides from the seeds of
Thevetia peruviana and their pro - apoptotic activity toward
cancer cells . -
pubmed
Cytotoxicity of them toward
cancer cell lines
P15 (
human lung cancer cell ) ,
MGC-803 (
human gastric cancer cells ) ,
SW1990 (
human pancreatic cancer cells ) , and normal hepatocyte cell
LO2 suggested that compound 1 could selectively inhibit the proliferation of
cancer cell lines with IC50 from 0.05 to 0.15 muM. -
pubmed
METHODS : The magnetic resonance imaging features of 20
patients of
anaplastic meningioma were compared with those of 30
patients of atypical
meningioma retrospectively , all of which were confirmed by surgery and pathology . -
pubmed
There were no postoperative symptoms of
urinary incontinence , and the
patient was completely satisfied . -
pubmed
Effects of diet composition on
weight loss , metabolic factors and biomarkers in a 1 - year
weight loss intervention in
obese women examined by baseline
insulin resistance status . -
pubmed
OBJECTIVE : To examine the effect of diet composition on
weight loss and metabolic , hormonal and inflammatory factors in
overweight /
obese women stratified by
insulin resistance status in a 1 - year
weight loss intervention . -
pubmed
METHODS AND RESULTS : Nondiabetic
women who were
overweight /
obese ( n=245 ) were randomly assigned to a lower fat ( 20 % energy ) , higher
carbohydrate ( 65 % energy ) diet ; a lower
carbohydrate ( 45 % energy ) , higher fat ( 35 % energy ) diet ; or a
walnut - rich ( 18 % energy ) , higher fat ( 35 % energy ) , lower
carbohydrate ( 45 % energy ) diet . -
pubmed
Prescribing
walnuts is associated with
weight loss comparable to a standard lower fat diet in a behavioral
weight loss intervention . -
pubmed
Disease progression was easily monitored by repeated quantification of
Gaussia princeps luciferase activity in peripheral blood . -
pubmed
MATERIALS AND METHODS : A prospective randomized open labeled clinical trial included 180
women with missed
miscarriage in gestational age between 13 and 24 wks . -
pubmed
Tubular epithelial cell - specific targeted deletion of
Grem1 ( TEC - grem1 - cKO ) mice displayed a milder response in the
acute injury and recovery phases of the
folic acid model . -
pubmed
Overweight dogs exercise less frequently and for shorter periods : results of a large online survey of
dog owners from the UK . -
pubmed
Canine
obesity is now the number one health concern in
dogs worldwide . -
pubmed
Information gathered included signalment ,
overweight status , and owner - reported information on duration and frequency of
dog walking . -
pubmed
Data were available from 11 154 adult
dogs , and 1801 ( 16 1 % ) of these were reported as
overweight by their owners . -
pubmed
Vicarious Social Defeat Stress Induces
Depression - Related Outcomes in Female
Mice . -
pubmed
Thus , the objective of the current investigation was to examine whether exposure to emotional and/or psychological stress ( ES ) mediates
depression - related outcomes in female
mice . -
pubmed
RESULTS : When compared with control
mice , female
mice exposed to ES displayed
decreased social behavior and preference for
sucrose , along with increased immobility in the tail suspension test . -
pubmed
CONCLUSIONS : Our data indicate that female
mice exposed to ES display a behavioral and physiologic profile that mimics symptoms of
depression in the clinical population . -
pubmed
Paroxysmal
Tonic Upgaze in
Children : Three Case Reports and a Review of the Literature . -
pubmed
In general , the entity was defined as an apparently benign phenomenon with normal investigations and eventual complete resolution of the symptoms , although some authors reported on
patients with associated
neurologic signs , such as
ataxia ,
developmental delay , and abnormal brain magnetic resonance imaging finding . -
pubmed
Paroxysmal tonic upgaze attacks have decreased in number or disappeared in 2
patients , but 1
patient exhibited mild abnormalities on magnetic resonance imaging and had relatives with
epilepsy . -
pubmed
It is important to recognize the clinical presentation of paroxysmal
tonic upgaze and distinguish the disorders from
epilepsy for deciding the treatment and prognosis of the
patients . -
pubmed
A novel experimental model for
human mixed
acinar - ductal pancreatic cancer . -
pubmed
In large part , this results from the lack of an
animal model that mimics
pancreatic cancer in
man . -
pubmed
We describe a novel experimental model of
pancreatic cancer that shares the genetic background , histologic features and natural history of
human mixed
acinar - ductal carcinoma . -
pubmed
This novel approach represents the first
pancreatic cancer model that does not involve alterations of embryonic development , which is inherent with
transgenic mice or knockout
mice models . -
pubmed
This novel experimental
human pancreatic cancer model can be used to more effectively test new anti -
cancer drug to inhibit
tumor progression in situ and to retard metastases . -
pubmed
Furthermore , our method of injecting
lentivirus containing oncogenes and molecules implicated in the development of pancreatic can be employed in
diabetic and
obese mice , two common metabolic conditions characterized by an increased incidence of
pancreatic cancer . -
pubmed
MATERIALS AND METHODS : The data included in this study were obtained from 352 renal transplant
patients who were consulted by the pulmonology department regarding
hemoptysis between 2011 and 2017 at Baskent University . -
pubmed
Hemoptysis was detected in 17
patients ( 4.8%),with 3 ( 0.85 % ) having massive
hemoptysis as a result of diffuse
alveolar hemorrhage syndrome . -
pubmed
Fourteen of our patient group ( 4 % ) had
pneumonia , and Aspergillus species was detected in 5
patients ( 1.4 % ) . -
pubmed
CONCLUSIONS :
Hemoptysis is an important respiratory symptom in renal transplant
patients . -
pubmed
We studied 37
men with primary
IO diagnosed by liver histology . -
pubmed
Herein , we describe a
patient with red tattoo pigment - induced
granulomatous dermatitis that histologically revealed a very rare
granuloma annulare - like reaction . -
pubmed
Clinical presentation A 20 - year - old
male with a history of
tuberous sclerosis ,
X - linked intellectual disability , and
epilepsy presented to the emergency department with two days of
nausea ,
emesis ,
seizures , and two months of progressive
proptosis . -
pubmed
Objective : To observe the clinical effects of Huanshao Capsules ( HSC ) combined with
levocarnitine ( LC ) on
asthenospermia ,
oligospermia ,
teratozoospermia , and the semen parameters of the
patients . -
pubmed
METHODS : This randomized controlled clinical study included 186
infertility patients with
spleen and kidney asthenia . -
pubmed
Moreover ,
diabetic nephropathy (
DN )
rats model was induced by intraperitoneal injection of a small dose of
streptozotocin ( 45 mg / kg ) and high - fat diet and plus 5 %
glucose drinking water . -
pubmed
Relation between cutaneous and extracutaneous complications in pediatric
patients with
type 1 diabetes . -
pubmed
Background : The relationship between cutaneous and extracutaneous complications in pediatric
patients with
type 1 diabetes is unclear . -
pubmed
Objective : The objective of the current study is to investigate the relationship between
skin disorders and
diabetic microangiopathic changes in pediatric and adolescent
patients with
type 1 diabetes . -
pubmed
Patients and methods : Eighty
patients with
type 1 diabetes and 50 healthy controls were enrolled in the study . -
pubmed
The significant association between
diabetic nephropathy and
cutaneous lesions support the concept that
cutaneous lesion in
diabetes is a reflection of
diabetic angiopathy , highlighting the importance of identifying
patients at risk of other microvascular complications . -
pubmed
Randomized clinical trial to evaluate the efficacy of
prostaglandin F2alpha to treat
purulent vaginal discharge in lactating dairy
cows . -
pubmed
The objectives of this study were ( 1 ) to assess the effect of purulent
vaginal discharge ( PVD ) on reproductive performance using a 4 - point
vaginal discharge score ( VDS ) and ( 2 ) to evaluate the effect of
PGF2alpha treatment in
cows with
PVD on reproductive performance . -
pubmed
Holstein
cows ( n = 2,473 ) from 1 commercial dairy farm had their
vaginal discharge scored at 32 + - 3 d in milk ( DIM ) using a 4 - point scale . -
pubmed
The effect of VDS and the effect of
PGF2alpha in
cows with
PVD on reproductive performance were evaluated separately . -
pubmed
Although multiparous
cows with
PVD treated with
PGF2alpha had increased odds of pregnancy at first AI , no treatment effect was observed on the hazard of conceiving within 200 DIM . -
pubmed
Our results do not support the blanket use of
PGF2alpha as a treatment option in postpartum dairy
cows having
PVD . -
pubmed
To my knowledge , this is the first report of
downy mildew caused by
P. - pubmed
Our primary objective was to evaluate the impact of early
AKI episodes that are persistent or progressive in nature , on
patient outcomes and graft survival . -
pubmed
We evaluated the incidence density rate ( IDR ) of graft failure and the time to graft failure in
patients with persistent or progressive
AKI (
ppAKI ) as compared to controls . -
pubmed
Toxoplasma gondii is an obligate intracellular parasite responsible for
toxoplasmosis , which can cause severe disease in the fetus and immunocompromised individuals . -
pubmed
Additionally , the survival time of
mice immunized with rTgMIF was longer than that of the
mice in control groups after challenge
infection with virulent
T. - pubmed
Moreover , the number of brain tissue
cysts in vaccinated
mice was reduced by 62.26 % compared with the control group . -
pubmed
Our objective was to determine the frequency of different clinical outcomes in
patients presenting with
TM . -
pubmed
In total 131
patients of
TM were enrolled and treated as per standard protocol , and re - evaluated after eight weeks for assessment of clinical outcomes . -
pubmed
Out of 131 cases , 36.6 % of
patients had full recovery and 63.4 % had poor recovery while
recurrence occurred in 66.7 % cases . -
pubmed
In conclusion , although
aniseikonia was gradually relieved after RD surgery during a 1 - year follow - up period , approximately half of
patients had
aniseikonia and almost all of them had
micropsia . -
pubmed
The objective of this study was to compare thyroid function between suicide attempters and non - suicide attempters in a large sample of first episode drug naive ( FEDN )
MDD patients , which received little systemic investigation . -
pubmed
METHODS : A total of 1718
outpatients with diagnosis of
MDD at their first episode were recruited . -
pubmed
In our retrospective statistical study we evaluated the autoantibody test results of serum and CSF from 2362
patients with suspected
PNS and 1034
patients with suspected
AE . -
pubmed
The number of
patients with suspected
PNS and
AE shows an increasing tendency , where the autoantibody testing with modern laboratory diagnostic methods helps in the early introduction of the appropriate therapy . -
pubmed
As an important derivative of the herb medicine
Artemisia annua L. ,
dihydroartemisinin (
DHA ) exhibits
anti - hepatocellular carcinoma (
HCC ) activities . -
pubmed
One
patient had bilateral trochanteric
ulcers . -
pubmed
Six major challenges were identified for CAMH policy in LMICs : ( i ) poor public awareness and low political willingness ; ( ii ) stigma against
mental disorders ; ( iii ) biased culture values toward children , adolescents and CAMH , from developmental nihilism to medicalization ; ( iv ) the lack of CAMH data and evidence , from service statistics to program evaluation ; ( v ) the shortage of CAMH resources , including
human resources , service facilities , and funding ; and ( vi ) unintended consequence of international support , including reducing local responsibilities , planning fragmentation , and unsustainability . -
pubmed
In this study , we combine MRI acquired from a large typically - developing childhood population ( n=768 ) with comprehensive
human gene expression databases to test the hypothesis that disrupted mechanisms common to
neurodevelopmental disorders are encoded by genes expressed early in development and nested within those associated with typical cortical remodelling in childhood . -
pubmed
OBJECTIVE : The aim of this study was to compare the incidence of
hypotension with
norepinephrine infusion or leg wrapping with a control group in
women undergoing caesarean delivery with spinal anaesthesia . -
pubmed
In group
Norepinephrine , the
women received a
norepinephrine infusion according to their
body weight , while group Leg Wrapping and the control group received a 0.9 % normal saline infusion at a similar rate . -
pubmed
BACKGROUND : This study determined whether the relationship between predicted
propofol effect site concentration ( Ce ) and observer 's assessment of alertness / sedation scale ( OAA / S ) or Bispectral Index ( BIS ) was similar comparing cognitively intact vs impaired
patients undergoing
hip fracture repair with spinal anesthesia and sedation . -
pubmed
In vitro and in vivo studies in
rodent models also indicate a bone - protective role for
resveratrol , particularly in ovariectomised
rat models that mimic
postmenopausal osteoporosis caused by
estrogen deficiency . -
pubmed
Regular supplementation with 75 mg of
resveratrol twice daily has the potential to slow
bone loss in the lumbar spine and femoral neck , common
fracture sites in postmenopausal
women without overt
osteoporosis . -
pubmed
Patients with miscellaneous risk factors were older ( p<0.01 ) , and had higher rates of
hypertension ( p=0.01 ) and
hyperlipidaemia ( p=0.04 ) . -
pubmed
For SAT1 , SAT2 , and
serotype A viruses , the genetic diversity is reflected in antigenic variation , and indications are that vaccine
strains may be needed for each topotype . -
pubmed
Although the precise mechanism of transmission of
FMD from
buffalo to
cattle is not well understood , it is facilitated by direct contact between these two species . -
pubmed
Once
cattle are infected they may maintain
SAT infections without the further involvement of
buffalo . -
pubmed
A deep analysis using panel - based next - generation sequencing in an Ecuadorian pediatric
patient with
anaplastic astrocytoma : a case report . -
pubmed
BACKGROUND :
Anaplastic astrocytoma is a rare disorder in
children from 10 to 14 years of age , with an estimated 0.38 new cases per 100,000 people per year worldwide . -
pubmed
Because it has never been genetically studied in the Ecuadorian population , we chose to genetically characterize an Ecuadorian pediatric
patient with
anaplastic astrocytoma for the first time . -
pubmed
The purpose of our study was to compare the safety and effectiveness of MT for
patients with
tBAO compared to those with non - tandem
basilar artery occlusions (
ntBAO ) . -
pubmed
RESULTS : A total of 15
patients with
tBAO and 74
patients with ntBAO were enrolled . -
pubmed
Successful reperfusion ( modified thrombolysis in
cerebral infarction score > = 2b ) was obtained in 73.3 % versus 90.5 % ( OR = 0.29 , 95%CI : 0.07 - 1.15 ) , good clinical outcome ( 3 - months modified Rankin scale < = 2 ) was reached by 26.7 % versus 32.4 % ( OR = 0.76 ; 95 % CI : 0.24 - 2.63 ) and mortality at 3 - months was 46.7 % versus 31 % ( OR = 1.94 ; 95%CI : 0.63 - 6 ) of
patients with
tBAO versus ntBAO , respectively . -
pubmed
Two
patients ( 13.3 % ) with
tBAO and three ( 4 % ) with ntBAO had symptomatic
intracranial haemorrhage ( OR = 3.64 ; 95 % CI : 0.55 - 24 ) . -
pubmed
CONCLUSION : Mechanical thrombectomy for
patients with tandem
basilar artery occlusion tends to be associated with lower rates of successful reperfusion and good clinical outcome , and higher rate of mortality . -
pubmed
Volunteers aged 7 - 17.9 years without a known history of
liver disease were recruited at four sites for a research MRI and blood draw between February 2018 and October 2019 . -
pubmed
Conclusion Mean liver stiffness measured with MR elastography in
children without
liver disease was 2.1 kPa ( similar to that in adults ) . -
pubmed
PURPOSE :
Patients with advanced
esophageal cancer have a poor prognosis and limited treatment options after first - line chemotherapy . -
pubmed
PATIENTS AND METHODS : In this open - label , phase III study , we randomly assigned ( 1:1 ) 628
patients with advanced / metastatic
squamous cell carcinoma or
adenocarcinoma of the esophagus , that progressed after one prior therapy , to
pembrolizumab 200 mg every 3 weeks for up to 2 years or chemotherapy ( investigator 's choice of
paclitaxel ,
docetaxel , or
irinotecan ) . -
pubmed
Median OS was 8.2 months versus 7.1 months ( HR , 0.78 [ 95 % CI , 0.63 to 0.96 ] ; P = .0095 ) in
patients with
squamous cell carcinoma and 7.1 months versus 7.1 months ( HR , 0.89 [ 95 % CI , 0.75 to 1.05 ] ; P = .0560 ) in all
patients . -
pubmed
CONCLUSION :
Pembrolizumab prolonged OS versus chemotherapy as second - line therapy for advanced
esophageal cancer in
patients with PD - L1 CPS > = 10 , with fewer treatment - related adverse events . -
pubmed
Elevated concentrations of serum
phosphate are linked with progression and increased case fatality rate in animals and
humans with
chronic kidney disease . -
pubmed
In
rodents , an excess intake of dietary
phosphorus combined with an inverse dietary
calcium :
phosphorus ratio ( < 1 : 1 ) contributes to
renal calcification . -
pubmed
Renal injury also has occured in
cats fed experimental diets supplemented with highly soluble
phosphate salts , especially in diets with inverse
calcium :
phosphorus ratios . -
pubmed
No data currently shows that commercial
cat foods induce
renal injury . -
pubmed
A fecal filtrate of
human origin containing the Norwalk agent of epidemic
viral gastroenteritis was administered by stomach tube to
chimpanzees in an attempt to induce
diarrheal disease . -
pubmed
The availability of the
chimpanzee as an experimental animal host susceptible to
infection with the Norwalk agent should facilitate the study of epidemic
viral gastroenteritis . -
pubmed
Prevention of
thrombosis in
patients on hemodialysis by low - dose
aspirin . -
pubmed
The study was continued until there were 24
patients with
thrombi and both groups had been under observation for a mean of nearly five months . -
pubmed
Thrombi occurred in 18 of 25 ( 72 per cent ) of
patients given placebo and 16 of 19 ( 32 per cent ) of those given
aspirin ( P less than 0.01 ) . -
pubmed
The incidence of
thrombosis was reduced from 0.46
thrombi per
patient month in the placebo group to 0.16
thrombi per
patient month in the
aspirin group ( p less than 0.005 ) . -
pubmed
Pyracetam also facilitates the process of teaching in
rats , improves the execution of a developed conditioned avoidance reaction , protects
rats against manifestations of retrograde
amnesia induced by an electric
shock , applied after development of the conditioned reflex of passive avoidance . -
pubmed
The prognosis and pathological findings in 44
patients with
breast cancer who had taken contraceptive
steroids during the year before diagnosis were compared with those in 44 controls matched for age and parity . -
pubmed
In
patients with
axillary node disease the
recurrence rate in the controls was significantly higher than in the study group and more of the control
patients had died . -
pubmed
Ganglioneuromas in
hamsters . -
pubmed
A description is given of three cases of
ganglioneuromas , which originated from ganglia of the sympathetic chain of
hamsters . -
pubmed
Other reports of such
tumors in this
species are reviewed and the literature relative to
hamster ganglioneuromas presented . -
pubmed
Differences were observed in
edema - forming ,
hemorrhage ,
defibrination , indirect
hemolysis ,
myonecrosis , proteolysis and lethal activity between venoms from different genera or species , as well as according to the geographic area of origin in
B. - pubmed
Structure of the granulocyte macrophage colony - stimulating factor gene in
patients with the
myelodysplastic syndromes . -
pubmed
Intimal changes at the prelesional stage of
atherosclerotic lesions were investigated ultrastructurally using
hamsters fed a high
cholesterol diet for 1 day to 1 month . -
pubmed
Adult
salicylate poisoning :
deaths and outcome in
patients with high plasma
salicylate concentrations . -
pubmed
The clinical features , plasma
salicylate concentrations , acid - base abnormalities and other biochemical findings are presented for 97
patients who either died from acute
salicylate overdosage or survived maximum recorded plasma
salicylate concentrations of 700 mg / l or greater . -
pubmed
[ 1,2 - Bis ( 2,6 - dichloro-4 - hydroxyphenyl ) ethylenediamine ] dichloro - platinum ( II ) ,
( C ) , a
platinum complex with endocrine activity and a specific effect on hormone - dependent
mammary tumors , was tested for its
tumor - inhibitory activity in the hormone - sensitive
R 3327 and Nb
prostate carcinoma models of the
rat and for its endocrine activities in comparison to the ligand L and
diethylstilbestrol (
DES ) . -
pubmed
Established
tumors of the
R 3327 prostate tumor were strongly inhibited by C. Its effect equaled that of
DES and was significantly better than that of L. Accessory sex organ weights and
testosterone levels were strongly reduced by C as well as L. This antigonadotrophic effect , which is almost comparable to
DES , was confirmed in 10 day experiments with intact , mature
mice and
rats , whereas a direct antiandrogenic activity was not given . -
pubmed
Pain and the laboratory
animal . -
pubmed
[ Comparative electrooculographic study of normal subjects and
patients with
demyelinating disease ] . -
pubmed
But recording of auditory evoked potentials is helpful in excluding
brain death in certain
patients . -
pubmed
Oral transfer of biliary immunoglobulins collected from infected
rats at various times during a primary
infection provided no protection to pups . -
pubmed
In one of the
patients caseous
tuberculosis of the bronchopulmonary , peribronchial and periportal lymph nodes was found , too . -
pubmed
In 48 normotensive
patients successful analgesia was achieved ; in seven
hypertensive patients , four were
pain - free , but the other three required more
lidocaine to achieve adequate analgesia . -
pubmed
Amoxapine for the treatment of psychotically
depressed subjects . -
pubmed
Factors influencing phenotypic diversity of
human prostate carcinoma cells metastasizing in athymic
nude mice . -
pubmed
Three related
human prostate carcinoma cell lines ,
PC-3 , 1 - LN -
PC-3 - 1A ( 1 - LN ) , and 1 - LN -
PC-3 - 1A clone 4 ( clone 4 ) were compared in terms of relative metastatic capacity in adult and young male
nude mice . -
pubmed
Only 1 - LN produced
lung metastases after intravenous injection into both 6- to 8 - week - old and 4 - week - old
nude mice , as well as in
mice injected intraperitoneally . -
pubmed
The extent of the phenotypic diversity exhibited by these
human prostate tumor lines was influenced by inherent dissemination ability , age of the host , and route of injection . -
pubmed
These lines provide a useful system for the analysis of the biology of
human tumor metastasis in
nude mice . -
pubmed
[ Value of studies of color perception thresholds in the diagnosis of partial
atrophy of the optic nerve in
children ] . -
pubmed
Minimal
bone marrow damage in
mice given
bleomycin . -
pubmed
[ Prethrombotic condition of
patients with
hypertensive disease and
arteriosclerosis ] . -
pubmed
[ Pathological anatomy of
encephalic tumors in
children ] . -
pubmed
Two methods of carrier detection were applied to the siblings of two
children with
congenital adrenal hyperplasia due to
21 - hydroxylase ( 21 - OH ) deficiency . -
pubmed
In the relationship between viruses and
cancer , viruses and
chronic diseases , or inanimate pathogens like
tobacco and
lung cancer , we know very little as to the factors that result in clinical disease among the many who are presumably susceptible and fully exposed . -
pubmed
Transient focal liver scan defects in
children receiving chemotherapy (
pseudometastases ) . -
pubmed
Three pediatric
patients with
tumors ( two
rhabdomyosarcoma , one
Wilms tumor ) had significant focal defects on
Tc-99 m sulfur colloid scans while receiving chemotherapy ( all three had received chemotherapy , including
actinomycin D , within ten days prior to scanning ) . -
pubmed
The finding of defects on liver scans of pediatric
patients receiving chemotherapy must not be automatically assumed to be
metastatic disease ; the changes may relate to hepatic response to recently administered chemotherapy . -
pubmed
Hepatocytes isolated from livers of
rats with various models of acute
uremia ( binephrectomy , ureter ligation ,
uranyl nitrate - induced , or ischemic
ARF ) were incubated with
glucagon ,
adrenalin , or
cyclic AMP using
serine as a substrate . -
pubmed
The correlation between
glucose concentration and the cytosolic redox state was different in control and sham - operated
rats than in either
uremic group . -
pubmed
This study confirms earlier investigations of a key role of
serine in
carbohydrate metabolism in acutely
uremic rats . -
pubmed
A case of a 55 - year old
patient is presented with
terminal renal insufficiency and a massive
prostatic adenoma causing
urinary tract obstruction . -
pubmed
Twenty - eight
patients with inoperable or metastatic
gastric cancer were treated with combination chemotherapy using
5 - fluorouracil ,
adriamycin and
mitomycin - C (
FAM ) . -
pubmed
Over an eight - year period , 19 ( 7.4 % ) of 257
patients with
penetrating trauma had
endophthalmitis develop , and 19 ( 31.1 % ) of 61 cases of
endophthalmitis were due to
trauma . -
pubmed
Eleven ( 10.7 % ) of 103
patients with intraocular
foreign bodies had
endophthalmitis develop . -
pubmed
Forty - five hospitalized
patients suffering from a moderate to severe nonpsychotic major
depressive disorder were clinically subdivided into three groups : endogenous ( n = 20 ) ,
neurotic ( n = 19 ) , and " ambiguous " ( n = 6 ) . -
pubmed
One thousand lines of a balanced lethal
strain of
Drosophila melanogaster heterozygous at seven allozyme loci were subjected to chronic ( 0.15 rad / min ) gamma - irradiation ( 137Cs ) . -
pubmed
In
patients with
cochlear deafness , this bandwidth is greatly enlarged , ranging from 0.42 - 2.2 octaves . -
pubmed
[ Enteric
dysentery vaccines and their effectiveness in a
rabbit intestinal loop model . -
pubmed
The residual virulence of attenuated vaccinal
strains of
Shigella administered into the intestinal loops ] . -
pubmed
sonnei
strain , attenuated
Sh . - pubmed
This indicates that vaccine
strains have insignificant residual virulence and suggests that the intestinal loop models , together with other models , may be used for testing the safety of vaccines prepared from
Shigella strains . -
pubmed
Genotypic characterization and clinical evaluation of the attenuated
A / California / 10 / 78 ( H1N1 ) recombinant
strain RIT 4265 . -
pubmed
The water proton NMR spin - lattice relaxation time if measured in
HEp-2 cells in relation to the
infection by different viruses (
Poliovirus type 1 ,
Coxsackievirus B-3 ,
human Adenovirus ,
Measles virus ,
Respiratory Syncytial virus ,
Herpes simplex virus , subtype 1 , and
Vaccinia virus ) . -
pubmed
Also the 74 test persons of the
acetyl salicyl acid group and 88 test persons of the control group who remained after subtraction of all deceased and dismissed
patients in the semiquantitative judgment of the progression of
macroangiopathy (
ischaemic heart disease ,
chronic venous insufficiency ,
arterial occlusive disease ,
vascular calcification ) and in the development of
retinopathy no significant differences in the sense of the effect of
acetyl salicyl acid expected could be recognized . -
pubmed
Controlled neuropsychological investigation of
patients with
neurotic excoriations . -
pubmed
A 57 - year - old
man with manifestations of
Marfan syndrome was referred for detail examination of
cardiac murmur to our hospital . -
pubmed
We examined the
retinal toxicity and intraocular pharmacokinetics of intravitreal
norfloxacin in
rabbits . -
pubmed
METHODS : Twenty - three albino and 23 pigmented
rabbits were divided into three groups to evaluate
retinal toxicity and two groups to investigate the intraocular pharmacokinetics . -
pubmed
The genetic background of
polygenic hypercholesterolemia was studied in hypercholesterolemic
children consuming a diet identical to control individuals with low
cholesterol concentrations . -
pubmed
The effects of exercise and stress on regional and whole body adiposity were examined in an established
animal model of diet - induced
coronary artery atherosclerosis , the
cynomolgus monkey (
Macaca fascicularis ) . -
pubmed
A 32 yr old
woman presented with intermittent
intermenstrual bleeding , 7 mths after a first trimester termination of pregnancy . -
pubmed
An additional 19
patients , not coded for
shoulder dystocia , sustained 14
fractured clavicles and five
brachial plexus injuries . -
pubmed
Response of
type I atrial fibrillation to atrial pacing in
humans . -
pubmed
The purpose of this study was to assess the local and left atrial response to pacing at the high right atrium during
type I AF in
humans . -
pubmed
METHODS AND RESULTS : Pacing was performed at the high right atrium during
type I AF in 24
patients in the electrophysiology laboratory . -
pubmed
Local capture of the right atrium during
AF was demonstrated for at least one pacing cycle length in each
patient . -
pubmed
Prompt volume replacement and diuresis is the cornerstone of therapy in preventing
acute renal failure in
patients who develop
rhabdomyolysis and
myoglobinuria . -
pubmed
CLINICAL RELEVANCE : Flow cytometric techniques may be useful for detection of
prothrombotic disorders in
horses . -
pubmed
Hypertension was induced in male
Sprague - Dawley rats ( n=40 ) by suprarenal
aortic coarctation . -
pubmed
However , the short chain analogue of the
indolinic nitroxide and the
quinolinic nitroxide had a negative effect on
trout hemolysis , contrary to what has already been observed in previous studies on
human RBCs ( red blood cells ) . -
pubmed
Elevated lipogenesis is a key determinant of exaggerated fat deposition in adipose tissue of
obese Zucker
rats . -
pubmed
Growth failure is a frequent side effect of long - term high - dose glucocorticoid therapy in
children . -
pubmed
Poor - grade
subarachnoid hemorrhage patients : the use of
nimodipine and other optional treatments . -
pubmed
The use of
calcium antagonists has been advocated as decreasing morbidity and mortality in
patients with
subarachnoid hemorrhage (
SAH ) following
aneurysm rupture . -
pubmed
A temporal MRI assessment of neuropathology after transient
middle cerebral artery occlusion in the
rat : correlations with behavior . -
pubmed
The purpose of this study was to evaluate the temporal and spatial pathological alterations within ischemic tissue using serial magnetic resonance imaging ( MRI ) and to determine the extent and duration of functional impairment using objective behavioral tests after transient
middle cerebral artery occlusion (
tMCAO ) in the
rat . -
pubmed
This long - term study is the first of its kind in tracing the dynamic pathologic and functional consequences of
tMCAO in the
rat . -
pubmed
Nowadays , the buffer used is
lactate , and its concentration in conventional peritoneal dialysis fluids is 35 or 40 mmol / L. Despite the general thought that peritoneal dialysis adequately corrects uremic
acidosis , several studies have demonstrated that more than 50 % of
patients present mild to moderate
acidosis with the solution containing 35 mmol / L of
lactate , although with a 40 mmol / L solution this percentage decreases , a substantial number of patients still remain
acidotic . -
pubmed
It has been demonstrated that
bicarbonate solutions have better biocompatibility than the
lactate buffered solution and substantially reduce
abdominal discomfort experienced by a certain percentage of
patients during the solution infusion . -
pubmed
BACKGROUND : Intravenous administration of radiographic
contrast agents is an important cause of
acute renal failure , accounting for one third of the cases of hospital - acquired
acute renal failure in
patients with native kidneys . -
pubmed
As
patients with renal transplantation may be at a higher risk of contrast - induced
nephrotoxicity (
CIN ) due to concomitant use of
cyclosporine and higher prevalence of
diabetes and
renal insufficiency , we retrospectively studied development of
CIN in these
patients . -
pubmed
The following were the various ICS done in these
patients : coronary angiogram ( 6 ) , CT scan with intravenous contrast ( 11 ) , angiogram for evaluation of
peripheral vascular disease ( 11 ) , allograft angiogram with angioplasty ( 5 ) , pulmonary angiogram ( 1 ) and intravenous pyelogram ( 1 ) . -
pubmed
Fourty percent of
patients ( 14 of 35 ) had
diabetes , and 25.7 % ( 9 of 35 ) had chronic rejection . -
pubmed
Two of these
patients were excluded from the analysis as renal functions in these
patients had deteriorated prior to ICS and
renal failure was attributed to
sepsis . -
pubmed
Of the remaining 7
patients , 5 had
diabetes and 2 had chronic rejection . -
pubmed
Only 4 of these 7
patients with
CIN received prophylaxis ( I / V hydration ) prior to ICS . -
pubmed
The baseline serum
creatinines were not different in
patients who had no change in renal function to those who developed
CIN ( 1.97 + /- 0.20 vs 1.54 + /- 0.17 mg / dl , p = 1.5 , mean + /- SEM ) . -
pubmed
More than 50 % increase in baseline serum
creatinine was seen in only 3 of these 7
patients , 2 of these
patients had
diabetes and third had chronic rejection and
congestive heart failure . -
pubmed
None of these
patients received prophylaxis for
CIN . -
pubmed
Three
patients also had a & gt ; 25 % decrease in baseline serum
creatinine after ICS , and all of them had allograft angiography with angioplasty for
renal artery stenosis . -
pubmed
CONCLUSION : In our retrospective study , the incidence of
CIN in renal allograft recipients applying a broader classification of & gt ; or = 25 % increase in baseline serum
creatinine was 21.2 % ( 7 of 33
patients ) . -
pubmed
The incidence of
CIN was lower 15.3 % ( 4 of 26 ) in
patients who received intravenous hydration compared to 42.8 % ( 3 of 7 ) in
patients who received no prophylaxis prior to ICS . -
pubmed
In order to better understand the mechanisms behind the rapid expansion of these
strains , the virulence of 10 clinical and two transformed
PNSP strains were compared with the virulence of three fully susceptible
strains in a
mouse model of
bacteremia and a
rat model of
acute otitis media . -
pubmed
New
rat model that phenotypically resembles
autosomal recessive polycystic kidney disease . -
pubmed
Numerous
murine models of
polycystic kidney disease (
PKD ) have been described . -
pubmed
While
mouse models are particularly well suited for investigating the molecular pathogenesis of
PKD ,
rats are well established as an experimental model of renal physiologic processes . -
pubmed
Han : SPRD - CY :
rats have been proposed as a model for
human autosomal dominant
PKD . -
pubmed
In the mutants , the renal cystic phenotype resembles
human autosomal recessive PKD (
ARPKD ) . -
pubmed
It is concluded that the clinical and renal histopathologic features of this new
rat model strongly resemble those of
human ARPKD . -
pubmed
We report a 56 - year - old
woman with this disorder who presented unusually with
respiratory failure and who initially had absent responses to phrenic nerve stimulation bilaterally . -
pubmed
The mechanism of the
patient 's
respiratory failure may have been chronic conduction blocks in the phrenic nerves leading to
diaphragmatic weakness . -
pubmed
When DNA mismatch repair fails , the result is a mutator phenotype , which can lead to
cancer in
humans . -
pubmed
The indices of local nonspecific lung protection in the bronchoalveolar lavage fluid and cells were studied in 20
patients with acute
pneumonia and 20
patients with lingering
pneumonia . -
pubmed
In the
patients with lingering
pneumonias who underwent a course of conventional therapy , these indices fail to recover to a greater extent , neutrophilic lung remained high . -
pubmed
Fifteen cases of
children with
congenital nasal pyriform aperture stenosis were reviewed for presentation of the disorder , management , and effectiveness of treatment , making it the largest series to date . -
pubmed
Preoperative symptoms of
upper airway obstruction were improved in all
patients at an average follow - up of 2.4 years ( range , 1 month to 5 years ) . -
pubmed
We report a case of a
patient with symptomatic pacemaker - mediated
tachycardia (
PMT ) . -
pubmed
PMT should be suspected when asynchronous pacing induced by magnet application causes temporary resolution of an unknown
tachycardia in a
patient with a pacemaker . -
pubmed
We present recent advances in our understanding of cellular patterns in the
vertebrate retina and the mechanisms that underlie their assembly , the ability of adult
anamniote retinas to regenerate following
injury , and how these seemingly disparate topics can be successfully merged into an effort to better understand both processes . -
pubmed
After administering a single intraperitoneal injection of
streptozotocin ( 60 mg / kg ) to
Sprague - Dawley rats and ensuring the induction of
diabetes at the end of 24 h ,
celecoxib was administered b.i.d . -
pubmed
Furthermore , the retinal vascular leakage estimated as vitreous to plasma protein ratio increased in
diabetic animals from 0.35+/-0.1 to 1.1+/-0.1 and
celecoxib treatment significantly decreased this ratio to 0.4+/-0.1 . -
pubmed
Deficits in PPI have been repeatedly reported in
patients with
schizophrenia or other
psychiatric disorders characterized by
abnormalities in sensory , cognitive , or motor gating . -
pubmed
Because some forms of
schizophrenia appear to be attributable to early developmental perturbations , many
animal studies have examined the influences of various developmental manipulations on PPI in adulthood . -
pubmed
Thus , social isolation rearing of
rats provides a developmentally specific , non - pharmacological manipulation that leads to deficits in sensorimotor gating that mimic those observed in
schizophrenia patients and are responsive to antipsychotic medications . -
pubmed
In the present study , we investigated whether
SU5416 could augment
cisplatin - induced
cytotoxicity in
human ovarian cancer cells . -
pubmed
The
fistula completely healed in 15 surgically treated
patients ( 17.4 % ) and 71 conservatively treated
patients ( 82.6 % ) , and in the follow - up observation ,
recurrence was identified in none of the cases . -
pubmed
The antiinflammatory effect of the
methanol extract of the leaves of
Bambusa arundinacea against
carrageenin - induced as well as immunologically induced paw
oedema and also its antiulcer activity in
albino rats have been studied and found to be significant when compared to the standard drugs . -
pubmed
Thus , the combination of herbal product (
methanol extract of
Bambusa arundinacea ) with modern medicine ( NSAIAs ) will produce the best antiinflammatory drug and will be useful for long - term treatment of chronic inflammatory conditions like
rheumatoid arthritis with
peptic ulcer , which are common . -
pubmed
Nutritional factors and the production by
dietary choline deficiency of
cancer de novo in
mice . -
pubmed
[ Distribution of endovenous
Fe55 and
Fe59 in ferro - proteins in normal
rabbits and those on a
myopathic diet ] . -
pubmed
Comparison of immunities against
tuberculosis between the
guinea pigs treated with dead tubercle bacilli paraffin - oil vaccine and those treated with BCG , by the method of slide cell culture . -
pubmed
Inhibition of the
human enzyme is a possible strategy for the treatment of
bone - resorptive diseases such as
osteoporosis . -
pubmed
Characterization of blood pressure and morphological traits in cardiovascular - related organs in 13 different inbred
mouse strains . -
pubmed
,
systolic blood pressure , weight ( corrected by
body weight ) of several cardiac compartments and adrenals and kidneys , and histological correlates for kidneys and adrenals ] in male and female
mice from 13 different inbred
strains . -
pubmed
We selected
strains so that each major genealogical group would be represented and to conform to priorities set by the
Mouse Phenome Database project . -
pubmed
For instance , female AKR / J
mice had relatively higher
body weight and
systolic blood pressure values than their male counterparts , perhaps constituting an
animal model of the
metabolic X syndrome . -
pubmed
RESULTS : In 33
patients with pregnancy - induced
hypertension and in five
patients with exacerbation of preexisting
hypertension in pregnancy no point mutations were found at codon 810 in exon 6 . -
pubmed
Association of timing , duration , and intensity of
hyperglycemia with intensive care unit mortality in
critically ill children . -
pubmed
OBJECTIVE : To study the association of timing , duration , and intensity of
hyperglycemia with pediatric intensive care unit ( PICU ) mortality in
critically ill children . -
pubmed
PATIENTS : A total of 152
critically ill children receiving vasoactive infusions or mechanical ventilation . -
pubmed
CONCLUSIONS :
Hyperglycemia is common in
critically ill children . -
pubmed
A prospective , randomized trial of strict glycemic control in this subset of
critically ill children who are at high risk of mortality is both warranted and feasible . -
pubmed
SUBJECTS AND METHODS : The study group was comprised of 50 consecutive
patients diagnosed with
schizophrenia , 18 years of age and older attending the out - patient clinic of the Mental Health Center in Beer - Sheva , Israel . -
pubmed
PATIENT(S ): A 22 - year - old
woman with
TAR syndrome referred to our department with
primary amenorrhea . -
pubmed
Breast - feeding is a route of
HIV transmission from an
HIV infected mother to her infant . -
pubmed
HIV /
AIDS reference questions in an
AIDS service organization special library . -
pubmed
RESULTS : Classification of
AF in these discharged
patients included 74 ( 55 % ) with first - detected episode ; 28 ( 21 % ) with recurrent
paroxysmal AF ; 17 ( 13 % ) with recurrent persistent
AF ; and 16 ( 12 % ) with permanent
AF . -
pubmed
BACKGROUND : Reconstitution of immune function during potent antiretroviral therapy can prompt discontinuation of maintenance cytomegalovirus (
CMV ) therapy but has also been associated with sight - threatening inflammatory conditions including immune recovery
uveitis (
IRU ) . -
pubmed
Six
participants in
Group 1 and 3 participants in Group 2 developed
IRU on - study . -
pubmed
METHODS : We conducted a prospective study of 18
subjects with unilateral
Meniere ' s disease treated with intratympanic
gentamicin injection and followed all
subjects for 1 year . -
pubmed
RESULTS : During the follow - up period , 11
subjects ( " single - treatment group " ; 61 % ) had control of their
vertigo with a single
gentamicin injection . -
pubmed
The remaining 7
subjects ( " multiple - treatment group " ; 39 % ) experienced recurrent
vertigo that required a second injection of
gentamicin at a mean of 6 months after the first treatment . -
pubmed
The 11
subjects in the single - treatment group had significantly greater reduction of labyrinthine function after the first treatment , as measured by change in ipsilateral horizontal canal gain , than did the 7
subjects with
vertigo recurrence . -
pubmed
PURPOSE OF REVIEW : As the most common
arthritis and a leading cause of chronic disability ,
osteoarthritis is associated with substantial cost to the
individual and to society . -
pubmed
ND virus (
NDV ) is the only member of the avian paramyxovirus serotype 1 (
APMV1 ) causing
ND outbreak in bird flocks . -
pubmed
Here , we describe an effective and unprecedented method for detecting
NDV strains of all pathotypes . -
pubmed
Patients ( n=530 ) were prospectively categorized into defined
melanoma risk groups and followed by clinical and epiluminescence microscopy ( ELM ) examinations . -
pubmed
A 39 - year - old
man was scheduled for removal of right
adrenal tumor . -
pubmed
We observed
cytotoxic effects using drug concentrations corresponding to blood plasma levels achieved in
NB patients . -
pubmed
BACKGROUND : Lumbar supports are used in the treatment of
low back pain patients to make the impairment and disability vanish or decrease . -
pubmed
AIMS / HYPOTHESIS : To assess
thiamine status by analysis of plasma , erythrocytes and urine in
type 1 and type 2 diabetic patients and links to markers of
vascular dysfunction . -
pubmed
METHODS : Diabetic
patients ( 26 type 1 and 48 type 2 ) with and without
microalbuminuria and 20 normal healthy control
volunteers were recruited . -
pubmed
RESULTS : Plasma
thiamine concentration was decreased 76 % in
type 1 diabetic patients and 75 % in
type 2 diabetic patients : normal
volunteers 64.1 ( 95 % CI 58.5 - 69.7 ) nmol / l ,
type 1 diabetes 15.3 ( 95 % CI 11.5 - 19.1 ) nmol / l , p & lt ; 0.001 , and
type 2 diabetes 16.3 ( 95 % CI 13.0 - 9.6 ) nmol / l , p & lt ; 0.001 . -
pubmed
Renal clearance of
thiamine was increased 24 - fold in
type 1 diabetic patients and 16 - fold in
type 2 diabetic patients . -
pubmed
CONCLUSIONS / INTERPRETATION : Low plasma
thiamine concentration is prevalent in
patients with
type 1 and type 2 diabetes , associated with increased
thiamine clearance . -
pubmed
OBJECT : To determine the prevalence and incidence of
Staphylococcus aureus strains among preschool- and school - aged pupils and susceptibility of these
strains to antimicrobial materials . -
pubmed
The isolated
Staphylococcus aureus strains were tested for resistance to
methicillin by performing disc diffusion method using commercial discs ( Oxoid ) (
methicillin 5 microg per disk and
oxacillin 1 microg per disk ) . -
pubmed
RESULTS : A total of 292 ( 53.8 % )
Staphylococcus aureus strains were isolated and identified ( 113 ( 46.5 % ) from preschool- and 179 ( 59.7 % ) from school - aged pupils ) . -
pubmed
Six
methicillin - resistant
Staphylococcus aureus strains were isolated : two ( 1.8 % ) of them were from preschool - aged and four ( 2.2 % ) from school - aged pupils . -
pubmed
METHODS : Twelve elderly
volunteers ( mean age : 65.6+/-6.3 years ) were evaluated for
pain ( on a visual analogue scale , [ VAS ] ) , static balance ( as measured by the centre of foot pressure , [ COP ] ) and dynamic balance ( the " Timed Up and Go " [ TUG ] test ) . -
pubmed
In this paper , the case of a 58 - year - old
woman with an
amyloid tumor of the breast , which developed secondary to long - standing
rheumatoid arthritis , is presented . -
pubmed
The studies provide weak evidence that photosensitizing plants can be effective in conjunction with phototherapy , and moderate evidence that
Ginkgo biloba monotherapy can be useful for
vitiligo . -
pubmed
BACKGROUND : Increased oxidative stress is associated with various complications in hemodialysis (
HD )
patients . -
pubmed
METHODS : We examined the effect of
coenzyme Q10 (
CoQ10 ) administration on the plasma oxidative products and antioxidant capacity in 36
HD patients for 6 months . -
pubmed
RESULTS : The advanced oxidation protein products ( AOPP ) ,
malondialdehyde and the percentage of
ubiquinone in total
CoQ10 were significantly higher in
HD patients than in healthy
subjects before administration ( 0 month ) . -
pubmed
Oxygen radical absorbing capacity ( ORAC ) and
Trolox equivalent antioxidant capacity ( TEAC ) , indicators of total antioxidant capacity , were also paradoxically higher in the
HD patients at 0 month . -
pubmed
CONCLUSION : The
CoQ10 administration was partially effective for suppressing the oxidative stress in
HD patients . -
pubmed
concurrent
natural infections in Zambian
cattle , based on egg and worm counts . -
pubmed
infections while 32 % had
F. - pubmed
In particular , data show that
obesity in
human populations is associated with cognitive decline and enhanced vulnerability to
brain injury , while experimental studies in
animal models confirm a profile of heightened vulnerability and
decreased cognitive function . -
pubmed
This review will describe findings from
human and animal studies to summarize current understanding of how
obesity affects the brain . -
pubmed
Thus , enhanced understanding of the effects of
obesity and
obesity - related
metabolic dysfunction on the brain are especially critical as increasing numbers of
obese individuals approach advanced age . -
pubmed
The chondrodystrophic
canine , another sub - species on the other hand are almost totally devoid of notochordal cells and they develop
DDD profoundly and early . -
pubmed
Children at risk for
developmental coordination disorder : judgement of changes in action capabilities . -
pubmed
In three separate manipulations , a group of
children at risk for
developmental coordination disorder (
DCD ; five males , seven females ; mean age 11y 6mo [ SD 6.8mo ] who were at or below the 15th centile on the Movement ABC ) and a group of typically developing children ( TDC ; seven males , five females ; mean age 11y 3mo [ SD 6.8mo ] ) judged the limit of their standing horizontal reach ( HRmax ) under two conditions in which actual HRmax differed . -
pubmed
Nicotianamine and
histidine /
proline are , respectively , the most important
copper chelators in xylem sap of
Brassica carinata under conditions of
copper deficiency and excess . -
pubmed
The aim of the present study was to investigate the in vitro effects of 20 metal compounds using
rabbit ejaculated spermatozoa as a study model for
spermiotoxicity . -
pubmed
Eleven
patients were operated on for
nonunions of the distal phalanx . -
pubmed
Three
patients had developed
infection and four of them had
bone resorption after their initial treatments , which probably caused
nonunion . -
pubmed
One
patient had a
haematoma formation at the donor site . -
pubmed
BACKGROUND : Endoscopic thoracic sympathectomy ( ETS ) was overused for treating
patients with
hyperhidrosis in Taiwan . -
pubmed
METHODS : We invited all surgeons in Taiwan who performed five or more ETSs per year for treating
patients with
hyperhidrosis to join this study . -
pubmed
They agreed that observation or topical therapy was appropriate for
patients with mild
palmar hyperhidrosis , whereas ETS was appropriate for children , adolescents , and young and middle - aged adults who had severe symptoms . -
pubmed
CONCLUSION : Evidence - based consensus development is helpful in decreasing overuse of ETS in treating
patients with
hyperhidrosis in Taiwan . -
pubmed
Cyclophosphamide - induced
cardiotoxicity occurred , even though the
patient had both shown normal cardiac function before high - dose chemotherapy and had received a lower dose of
cyclophosphamide . -
pubmed
We describe our management of high - grade car tire
foot injuries in
children with free anterolateral thigh flap (
ALT ) . -
pubmed
Minor
gait abnormalities were detected in two of the
patients . -
pubmed
CONCLUSION : With minimal donor site morbidity , long vascular pedicle allowing anastomosis outside of the
trauma zone , we believe free
ALT flap provides the ideal soft tissue reconstruction for high grade car tire
injuries of foot in
children . -
pubmed
CATCH : a clinical decision rule for the use of computed tomography in
children with minor
head injury . -
pubmed
We aimed to develop a highly sensitive clinical decision rule for the use of CT in
children with minor
head injury . -
pubmed
METHODS : For this multicentre cohort study , we enrolled consecutive
children with
blunt head trauma presenting with a score of 13 - 15 on the Glasgow Coma Scale and
loss of consciousness ,
amnesia ,
disorientation , persistent
vomiting or
irritability . -
pubmed
Once the decision rule has been prospectively validated , it has the potential to standardize and improve the use of CT for
children with minor
head injury . -
pubmed
Extrahippocampal gray matter loss and hippocampal deafferentation in
patients with
temporal lobe epilepsy . -
pubmed
METHODS : Three different MRI studies were performed involving 23
patients with unilateral
MTLE ( 8 left and 15 right ) and 34 healthy controls : ( 1 ) voxel - based morphometry ( VBM ) , ( 2 ) diffusion tensor imaging ( DTI ) and ( 3 ) probabilistic tractography ( PT ) . -
pubmed
There was a decrease in hippocampal PT in
patients with
MTLE in limbic areas . -
pubmed
Arthropod - borne viruses ( arboviruses ) are a significant cause of
human and
animal disease worldwide . -
pubmed
The molecular biological methods revealed that these
strains differ from
P. - pubmed
In the present study , the complete genomic sequences of 9
DuCV strains , which were obtained by PCR screening from 90 dead or diseased ducks collected from different regions in China between 2008 and 2010 , were determined and compared with previously available
DuCV sequences in public databases . -
pubmed
DATA SYNTHESIS : The prevalence of
visual impairment in
children 5 years of age and younger is between 7 % and 8 % . -
pubmed
Treating
children younger than age years who have
cataracts or
strabismus may prevent the development of
amblyopia . -
pubmed
It is unclear whether treating young
children with
refractive errors associated with
amblyopia would prevent the development of
amblyopia . -
pubmed
Although early intervention is important for the prevention or treatment of
visual impairment , treatment of certain
refractive errors in
children younger than age 3 years may interfere with the development of the eye . -
pubmed
Astrocytes form a significant constituent of
seizure foci in the
human brain . -
pubmed
This article reviews the information now available on the role of astrocytes in the hippocampal
seizure focus in
patients with
temporal lobe epilepsy with
hippocampal sclerosis . -
pubmed
METHODS : Population - based study including 1388 participants ( 704
women ) older than 18 years in which 300 were untreated
hypertensive patients . -
pubmed
In 335 untreated
hypertensive patients referred to one
hypertension clinic , the study was replicated . -
pubmed
Loss of basement membrane integrity in
human gingival overgrowth . -
pubmed
Here we experimentally evaluate whether increased degradation of the basement membrane and apparent invasion of the underlying stroma by epithelial cells could be observed in
human gingival overgrowth tissues . -
pubmed
Tissues from 20 different
individuals with
human gingival overgrowth and 15 non - overgrowth samples were evaluated by histological analyses and by immunohistochemistry assays of basement membrane proteins . -
pubmed
Tasmanian devils (
Sarcophilus harrisii ) are on the verge of extinction due to a transmissible
cancer ,
devil facial tumour disease (
DFTD ) . -
pubmed
There was no significant difference in
deaths in hyper- and holoendemic areas , risk difference +1.93 per 1000 children ( 95 % CI -1.78 to 5.64 , 13 trials , 17,898
children ) . -
pubmed
[ Impact of age on treatment and outcomes after
acute myocardial infarction , particularly in very elderly
patients ] . -
pubmed
OBJECTIVES : To evaluate the presentation and treatment of
myocardial infarction according to age , particularly in very elderly
patients . -
pubmed
METHODS : We studied 1242 consecutive
patients admitted with
acute myocardial infarction , assessing in - hospital , 30 - day and one - year mortality during follow - up for each age - group . -
pubmed
RESULTS : Elderly
patients had a worse risk profile ( except for smoking ) , more previous history of
coronary disease and a worse profile on admission , with the exception of lipid profile , which was more favorable . -
pubmed
CONCLUSIONS : Elderly
patients represent a substantial proportion of the population admitted with
myocardial infarction , and receive less evidenced - based therapy . -
pubmed
Wistar rats were subjected to 5 , 10 and 20 mg / kg GB daily for 5 days , intraperitoneally , following
TBI . -
pubmed
Rats were sacrificed at hour 2 , 6 and 12 , as well as day 1 , 2 , 3 and 5 after
TBI . -
pubmed
For that purpose
cancer cells were injected into
mice and resulting hybridomas were screened for their ability to inhibit cell proliferation in vitro . -
pubmed
The influence of the location of the lesion on the absolute risk of the development of
skin cancer in a
patient with
actinic keratosis . -
pubmed
OBJECT : The authors retrospectively reviewed the efficacy and safety of Gamma Knife surgery ( GKS ) in
patients with
brainstem cavernous malformations (
CMs ) . -
pubmed
METHODS : Between 1993 and 2010 , 49
patients with symptomatic
CMs were treated by GKS . -
pubmed
All 49
patients experienced at least 2 instances of repeated
bleeding before GKS ; these
hemorrhages caused
neurological deficits including
cranial nerve deficits ,
hemiparesis ,
hemisensory deficits ,
spasticity ,
chorea or
athetosis , and
consciousness disturbance . -
pubmed
The pre - GKS annual
hemorrhage rate was 31.3 % ( 69 symptomatic
hemorrhages during a total of 220.3
patient - years ) . -
pubmed
In this study of 49
patients , symptomatic radiation - induced complications developed in only 2
patients ( 4.1 % ;
cyst formation in 1
patient and perifocal
edema with
neurological deficits in the other
patient ) . -
pubmed
CONCLUSION : Not only supine hemodynamics , but also responses to head - up tilt differed between normotensive and
hypertensive patients , indicating functional alterations beyond increased vascular resistance and higher arterial stiffness in
hypertension . -
pubmed
We present the results of a wild bird surveillance system for
A / H5N1 and other
avian influenza viruses based on avian fecal sampling in Kenya . -
pubmed
An electronic communication system for
amyotrophic lateral sclerosis patients - biomed 2013 . -
pubmed
A prospective evaluation of hemodynamic management in
acute spinal cord injury patients . -
pubmed
STUDY DESIGN : Prospective observational study of acute
spinal cord - injured (
SCI )
patients . -
pubmed
OBJECTIVES : To determine how effectively mean arterial blood pressure ( MAP ) and spinal cord perfusion pressure ( SCPP ) are maintained at target levels in acute
SCI patients . -
pubmed
METHODS : Twenty - one
individuals with
cervical or thoracic SCI were enrolled within 48 h of
injury . -
pubmed
Caffeic acid phenethyl amide improves
glucose homeostasis and attenuates the progression of
vascular dysfunction in
Streptozotocin - induced
diabetic rats . -
pubmed
BACKGROUND :
Glucose intolerance and
cardiovascular complications are major symptoms in
patients with
diabetes . -
pubmed
Many therapies have proven beneficial in treating
diabetes in
animals by protecting the cardiovascular system and increasing
glucose utilization . -
pubmed
In this study , we evaluated the effects of
caffeic acid phenethyl amide (
CAPA ) on
glucose homeostasis and vascular function in
streptozotocin (
STZ)-induced
type 1 diabetic rats . -
pubmed
METHODS :
Diabetes ( blood
glucose levels & gt ; 350 mg / dL ) , was induced in
Wistar rats by a single intravenous injection of 60 mg / kg
STZ . -
pubmed
Hypoglycemic effects were then assessed in normal and
type 1 diabetic rats . -
pubmed
RESULTS : Oral administration of 0.1 mg / kg
CAPA decreased plasma
glucose in normal ( 32.9 + - 2.3 % decrease , P & lt ; 0.05 ) and
diabetic rats ( 11.8 + - 5.5 % decrease , P & lt ; 0.05 ) . -
pubmed
CONCLUSIONS :
CAPA induced
hypoglycemic activity , increased coronary blood flow and vascular response to
phenylephrine in
type 1 diabetic rats . -
pubmed
CLINICAL RELEVANCE : These results encourage further studies on the potential use of these blue light - mediated auto -
photosensitization processes in the treatment of
periodontitis for the successful inactivation of
Aggregatibacter actinomycetemcomitans . -
pubmed
CONCLUSIONS AND RELEVANCE : A thicker cortex associated with a high importance of religion or spirituality may confer resilience to the development of
depressive illness in
individuals at high familial risk for
major depression , possibly by expanding a cortical reserve that counters to some extent the vulnerability that cortical thinning poses for developing familial
depressive illness . -
pubmed
Clinical outcome and prognostic factors of
patients with
hepatocellular carcinoma and extrahepatic
metastasis treated with
sorafenib . -
pubmed
METHODS : Sixty - one
HCC patients with extrahepatic metastasis who were treated with
sorafenib were enrolled in this retrospective cohort study . -
pubmed
Intrahepatic
tumor stage before treatment allows stratification of prognosis of
patients treated with
sorafenib . -
pubmed
Among the progressive disease group ,
patients with T0 - 2 intrahepatic
tumor stage had better prognosis than
patients with T3 - 4 . -
pubmed
CONCLUSION : In
HCC patients with extrahepatic metastasis who are treated with
sorafenib , intrahepatic
tumor stage was a significant and independent prognostic factor . -
pubmed
Although the mechanisms underlying osmoregulatory defects in individual patients are presumably diverse , we hypothesize that treatment responses and
patient outcomes will vary according to
SIAD subtype . -
pubmed
Human Bocavirus in Iranian children with
acute gastroenteritis . -
pubmed
The present study was aimed to determine the prevalence of
HBoV in children with
gastroenteritis . -
pubmed
Human Bocavirus positive samplesfrom patients aged between 1 to 5 years with
acute gastroenteritis infection suggest a minor role of HBoVin
gastroenteritis ( p=0.0001 ) . -
pubmed
CONCLUSION : The study showed a high prevalence of
human Bocavirus in young children with acute
gastroenteritisdiseases in Iran , suggesting that
HBoV play a role in the pathogenesis of
gastroenteritis . -
pubmed
Evaluation of
gabapentin in management of
hot flushes in postmenopausal
women . -
pubmed
This study was conducted to assess the efficacy of
gabapentin in controlling
hot flushes in postmenopausal
women . -
pubmed
Fifty postmenopausal
patients with
hot flushes were randomized in two groups , one receiving
gabapentin 900 mg daily along with
calcium and another group receiving
calcium alone . -
pubmed
Recurrent
arterial aneurysm rupture of the upper extremity in a
patient with
vascular - type Ehlers - Danlos syndrome . -
pubmed
Arterial
aneurysm rupture is one of the most critical complications in
patients with
vascular - type Ehlers - Danlos syndrome (
vEDS ) . -
pubmed
A 38 - year old
woman who underwent brachial artery ligation for a ruptured
aneurysm was diagnosed postoperatively with
vEDS . -
pubmed
Given that
arterial rupture can occur repeatedly in
patients with
vEDS , careful life - long follow - up is necessary . -
pubmed
MATERIALS AND METHODS : A
hyperuricemic animal model was created by administering
adenine and
allantoxanic acid potassium salt to
mice . -
pubmed
(
Campanulaceae ) has a long history of use as a traditional herbal medicine for the treatments of
cough ,
phlegm ,
sore throat ,
lung abscess ,
chest pain ,
dysuria , and
dysentery . -
pubmed
BACKGROUND :
Patients with or at high risk of
cardiovascular disease have a poor functional capacity ; however , the influence of association among
intermittent claudication ( IC ) , abnormal ankle - brachial index ( ABI ) , and physical activity level on functional capacity of these patients has not been fully studied . -
pubmed
PATIENTS AND METHODS : This was a prospective cross - sectional study in which 162 consecutive
patients were evaluated and classified into three groups according to their ABI : normal ABI ( n=104 , values between 1.00 and 1.40 ) ; borderline
PAD ( n=23 , values between 0.91 and 1.00 ) ; and patients with
PAD ( n=35 , & lt;=0.90 ) . -
pubmed
Here , we studied the efficacy and safety of prolonged - release
melatonin (
PRM ) , a registered drug for
insomnia , for
sleep disorders in totally blind
subjects living in normal social environments . -
pubmed
CONCLUSION : Nightly use of
PRM may potentially improve
patient - reported
sleep difficulties in totally blind individuals trying to adhere to normal social lifestyle . -
pubmed
A randomized , double - blind , phase 2 study evaluating the safety and efficacy of
AMG 416 for the treatment of
secondary hyperparathyroidism in hemodialysis
patients . -
pubmed
CONCLUSIONS : The present clinical findings support the continued development of
AMG 416 as a treatment for
SHPT in hemodialysis
patients . -
pubmed
The pathogenetic mechanism of
AU is still poorly defined , given its remarkable heterogeneity and the many discrepancies between experimental and
human uveitis . -
pubmed
Current guidelines recommend
corticosteroids as the first - line therapy for
patients with active
AU . -
pubmed
Metabolomic Study on the Preventive Effect of
Patrinia scabiosaefolia Fisch on Multipathogen Induced
Pelvic Inflammatory Disease in
Rats . -
pubmed
Sixteen differentiating metabolites contributed to the alteration of metabolic profile in
PID rats , including two
amino acids , three fat acids , nine organic acids , and two types of
sugars . -
pubmed
Abdominal radiography and ultrasonography are commonly used as part of the initial diagnostic plan for
cats with nonspecific signs of
abdominal disease . -
pubmed
We thus hypothesized that
fructose intake by
hypertensive rats would have a worse prognosis in developing
metabolic disorder and
non - alcoholic fatty liver disease . -
pubmed
Also ,
insulin resistance was observed in normotensive and mostly in
hypertensive rats after
fructose intake . -
pubmed
However , we found that
fructose intake significantly increased abdominal fat mass deposition in normotensive but not in
hypertensive rats . -
pubmed
Nevertheless , chronic
fructose intake only increased fat deposition and
fibrosis in the liver in
hypertensive rats . -
pubmed
CONCLUSIONS : We demonstrated that , in normotensive and
hypertensive rats ,
fructose intake increased
triglycerides and abdominal fat deposition , and caused
insulin resistance . -
pubmed
However ,
hypertensive rats that underwent
fructose intake also developed interstitial fat deposition and
fibrosis in liver . -
pubmed
Azole Resistance of
Aspergillus fumigatus in Immunocompromised Patients with Invasive
Aspergillosis . -
pubmed
Multimodality imaging not only allows diagnosis , characterization , and localization of
vascular abnormalities but also permits evaluation of natural history and complications , thus , facilitating optimal
patient management . -
pubmed
Morphologically , one of these
strains corresponded to
Gephyrocapsa ericsonii and the four others to
Reticulofenestra parvula . -
pubmed
Ribosomal gene sequences were near identical between these new
strains , but divergent from
G. - pubmed
Slow acetylators have a higher risk of development of
drug - induced toxicity , while fast acetylators and
immune - deficient patients face lower treatment success rates . -
pubmed
Importantly ,
tumor cells in 3D culture showed chemotherapy resistance patterns similar to those observed in
glioma patients . -
pubmed
As [ Saccharicrinis ] marinus Y11 T clustered phylogenetically with
strain HQYD1 T , we also propose [ Saccharicrinis ] marinus Y11 T be reclassified as
Labilibacter marinus comb . -
pubmed
Non - curative surgery for
patients with
gastric cancer with local peritoneal
metastasis : A retrospective cohort study . -
pubmed
This study aimed to evaluate the efficacy of non - curative resectional surgery for
patients with
GC with local peritoneal
metastasis . -
pubmed
We reviewed the medical records of 47
patients with
GC with local peritoneal
metastasis , which was found by laparotomy or laparoscopy . -
pubmed
The Kaplan - Meier survival curves revealed that resection group had longer survival than non - resection group ( P & lt ; 0.001).Non - curative resectional surgery helps prolong survival time and improve the quality of life for
patients with
GC with local peritoneal
metastasis . -
pubmed
The incidence and prognosis of
FNP after SSIAC in 381
patients with
oral cancer ( 133 with catheterization of the MA , 248 without ) was investigated retrospectively . -
pubmed
Only three
patients ( two male and one female ) had
FNP , for an incidence of 0.8 % . -
pubmed
All
patients with
FNP had undergone catheterization of the MA , and the incidence of
FNP in this group was 2.3 % ( 3/133 ) . -
pubmed
One of the three
patients with
FNP had
paralysis of the third branch of the trigeminal nerve . -
pubmed
Because the administration of anticancer agents via the
MA or
MMA carries a risk of
FNP , this information will be useful when obtaining informed consent from
patients before treatment . -
pubmed
METHODS : The sample included 40 male schizophrenic
patients with and 40 male schizophrenic patients without
substance use disorder comorbidity who had applied to Ankara Numune Research and Training Hospital . -
pubmed
Our goals were to identify risk factors associated with regional
recurrence and to determine whether a radiosensitivity index ( RSI ) gene expression signature ( GES ) could identify
patients who experience a survival benefit with regional RT . -
pubmed
Postoperative regional RT was associated with a reduced risk of regional
recurrence among all
patients on univariate ( 5 - year estimate : 95.0 % vs 83.3 % ; P=.036 ) and multivariate analysis ( hazard ratio[HR ] , 0.15 ; 95 % CI , 0.05 - 0.43 ; P<.001 ) . -
pubmed
Among higher - risk subgroups , regional RT was associated with a lower risk of regional
recurrence among
patients with clinically detected lymph nodes ( n=175 ; 5 - year regional control : 94.1 % vs 69.5 % ; P=.003 ) and
extracapsular extension ( ECE ) present ( n=138 ; 5 - year regional control : 96.7 % vs 62.2 % ; P<.001 ) . -
pubmed
Among a subset of radiated
patients with gene expression data available , a low RSI GES ( radiosensitive )
tumor status was associated with improved survival compared with a high RSI GES ( 5 - year : 75 % vs 0 % ; HR , 10.68 ; 95 % CI , 1.24 - 92.14 ) . -
pubmed
Conclusions : Regional RT was associated with a reduced risk of regional
recurrence among
patients with ECE and clinically detected
nodal disease . -
pubmed
Oral administration of
red ginseng powder fermented with probiotic alleviates the severity of dextran - sulfate
sodium - induced
colitis in a
mouse model . -
pubmed
In order to produce homogeneously effective
red ginseng , we prepared probiotic - fermented
red ginseng and evaluated its activity using a dextran sulfate
sodium ( DSS)-induced
colitis model in
mice . -
pubmed
Initial analysis of
intestinal damage indicated that the administration of probiotic - fermented
red ginseng significantly decreased the severity of
colitis , compared with the control and the activity was higher than that induced by oral administration of
ginseng powder or probiotics only . -
pubmed
Collectively , oral administration of probiotic - fermented
red ginseng reduced the severity of
colitis in a
mouse model , suggesting that it can be used as a uniformly effective
red ginseng product . -
pubmed
OBJECTIVE : To evaluate the long - term clinical and imaging efficacy of
etanercept in
patients with early , active
nonradiographic axial spondyloarthritis (
SpA ) . -
pubmed
METHODS : Adult
patients who satisfied the Assessment of SpondyloArthritis international Society ( ASAS ) classification criteria for axial
SpA ( but not the modified New York radiographic criteria ) , with symptom duration & gt;3 months to & lt;5 years , and who were unresponsive to & gt;=2 nonsteroidal antirheumatic drugs ( NSAIDs ) received double - blind etanercept 50 mg / week or placebo for 12 weeks , followed by open - label etanercept 50 mg / week to week 104 . -
pubmed
At week 104 , 61 of 81 ( 75 % ) , 49 of 81 ( 61 % ) , 48 of 80 ( 60 % ) , and 57 of 81 ( 70 % )
patients who received
etanercept throughout the trial achieved ASAS20 , ASAS40 , Ankylosing Spondylitis Disease Activity Score ( ASDAS ) inactive disease , and Bath
Ankylosing Spondylitis Disease Activity Index criteria for 50 % improvement ( BASDAI 50 ) scores , respectively ( observed ) . -
pubmed
CONCLUSION :
Patients with early , active nonradiographic axial
SpA and an inadequate response to at least 2 NSAIDs demonstrated improvement in clinical and imaging outcomes that were sustained through 104 weeks of
etanercept treatment . -
pubmed
Preterm birth continues to be a significant global health care issue , due to our lack of understanding of the mechanisms that drive
human labour and delivery . -
pubmed
Study of
gefitinib maintenance in unselected
patients with
metastatic primary lung adenocarcinoma : A descriptive study . -
pubmed
BACKGROUND : Maintenance treatment of
patients with advanced
nonsmall cell lung cancer (
NSCLC ) without
disease progression after first - line chemotherapy is a subject of ongoing research . -
pubmed
The major
toxicity observed was
rash /
acne in 15
patients ,
pruritus in 7
patients , and one patient had Grade 4
pneumonitis . -
pubmed
RESULTS : 14,290
patients were identified , 1294 ( 9.1 % ) developed
IH , 48 % within 1 - year , 33 % at 1 - 2 years , and 19 % at 2 - 3 years post - surgery . -
pubmed
Retinal detachment stabilizes during physical protection and posturing but progresses through bodily activity and during interruptions in
patients with macula - on
retinal detachment . -
pubmed
Retrospective observational cohort study on cosmetic outcome of using
Ti -
Ni memory alloy wire for intradermal suture following mastectomy in
patients with
breast cancer . -
pubmed
The method of suturing for incisions is crucial for the comprehensive treatment of clinical
patients with
breast cancer . -
pubmed
Furthermore , the mean number of days of
wound healing was significantly decreased for the active group compared with that for the control group ( P=0.0026 ) in the
patients with
diabetes . -
pubmed
In addition , the usage of
Ti -
Ni memory alloy wire was able to decrease the mean number of wound healing days between
patients with
diabetes and their non - diabetic counterparts ( P=0.7009 ) . -
pubmed
This technique may be useful for preventing
scar overgrowth and for facilitating the recovery process in
patients with
diabetes . -
pubmed
Ten - year survival was worse in
patients & lt ; 65 years old ( p = 0.035 ) , in those with
BMI & gt ; 30 ( p = 0.017 ) and in those with postoperative increases in
medial tibial sclerosis ( p & lt ; 0.001 log - rank ) . -
pubmed
METHODS : This prospective , non - randomized , controlled study involved
patients who had
cataract surgery with bilateral implantation of bifocal or trifocal IOLs . -
pubmed
The near , intermediate , and distance visual acuities , defocus curve , optical quality including modulation transfer functions and higher - order aberrations , National Eye Institute Visual Functioning Questionnaire-14 ,
patient satisfaction , spectacle independence , and perception of
visual disturbances were assessed in all
patients . -
pubmed
Craving Responses to
Methamphetamine and Sexual Visual Cues in
Individuals With
Methamphetamine Use Disorder After Long - Term Drug Rehabilitation . -
pubmed
Discovery and validation of genomic regions associated with resistance to
maize lethal
necrosis in four biparental populations . -
pubmed
The sudden outbreak of
maize lethal necrosis ( MLN ) disease is seriously threatening the
maize production in the region . -
pubmed
BACKGROUND :
Trypanosoma cruzi , the causal agent of
Chagas disease , is monophyletic but genetically heterogeneous . -
pubmed
Hepatocellular carcinoma (
HCC ) is a common
human malignancy . -
pubmed
The high rates of bone marrow involvement by these
lymphomas pose a major therapeutic challenge due to the chemotherapy - resistant nature of the bone marrow microenvironment and the limited utility of
rituximab - based salvage regimens in
patients with relapsed / refractory disease . -
pubmed
METHODS : The sample comprised 8
children of both sex , aged between 48 and 72 months with
WS . -
pubmed
We recruited
patients with obstructing
colorectal cancer from our registry . -
pubmed
Background : Long non - coding RNAs nowadays emerge as important biomarkers or potential therapeutic targets discussed in
human cancers . -
pubmed
Therapies in
Canine Atopic Dermatitis : An Update . -
pubmed
Canine atopic dermatitis (
AD ) is one of the most common
inflammatory skin diseases in
dogs . -
pubmed
This article provides a comprehensive review of the latest compounds for the treatment of
canine AD . -
pubmed
BACKGROUND :
Glioblastoma multiforme (
GBM )
patients with a prior
malignancy are usually excluded from clinical trials on
GBM based on the assumption that this history will affect their survival outcomes . -
pubmed
However , not much is known about the real impact of these prior
malignancies on the survival of
patients with subsequent
GBM . -
pubmed
PATIENTS AND METHODS : We used the Surveillance , Epidemiology , and End Results ( SEER ) Program to analyze data of
GBM patients diagnosed between 1973 and 2014 . -
pubmed
We calculated the overall and
GBM - specific survival of these
patients using the unadjusted Kaplan - Meier test and the multivariable covariate - adjusted Cox models . -
pubmed
RESULTS : Of 51,158
GBM patients , 3,076 had a prior
malignancy . -
pubmed
The kinetoplastid parasite
Trypanosoma brucei causes
African trypanosomiasis in both
humans and animals . -
pubmed
METHODS : Additional to standard therapy , eight
CRPS -
patients with symptoms of less than 12 months were treated with topical 20 %
ambroxol cream . -
pubmed
RESULTS : Following treatment we found a reduction of spontaneous
pain ( 6
patients ) ,
pain on movement ( 6
patients ) ,
edema ( seven
patients ) ,
allodynia ( six
patients ) ,
hyperalgesia ( seven
patients ) , reduction of
skin reddening ( four
patients ) , improvement of
motor dysfunction ( six
patients ) and improvement of skin temperature ( four
patients ) . -
pubmed
Although standard protocols for undertaking acute and
chronic toxicity tests of dissolved chemicals with
D. - pubmed
Here we describe the acute and
chronic toxicity methods with
D. - pubmed
We present the unusual case of a 40 - year - old
woman with multifocal
GCTs affecting the intrahepatic biliary tree , which were initially suspected to be hepatic multiple
metastases from a
malignancy of unknown origin . -
pubmed
Proteomics identification of radiation - induced changes of membrane proteins in the
rat model of
arteriovenous malformation in pursuit of targets for brain AVM molecular therapy . -
pubmed
Methods : We employed in vivo biotinylation methodology that we developed , to label membrane proteins in the
rat model of
AVM post radiosurgery . -
pubmed
DNA - DNA hybridization values between
strain THG - SD5.5 T and
C. - pubmed
These findings may explain the mechanism of increased vulnerability to
infection and
malignancy observed in older transplant
patients . -
pubmed
Endotoxin - resistant
sheep proved nonresponsive to minor
pulmonary embolism and to incompatible blood transfusion . -
pubmed
After
cerebral ischemia - reperfusion in
rats ,
DCA was administered continuously for 21 days ; following which , histological analysis , and cognitive functional tests were conducted . -
pubmed
Taken together , these findings suggested that long - term
DCA administration improved cognitive function in a
rat model of
VD , and did so in part , by improving EPC function . -
pubmed
Two ( 2.5 % )
patients had
AR , and 3 ( 3.8 % ) had efficacy failure . -
pubmed
The objective of this study was to determine whether regions of high - frequency Ripple activation ( HFRA ) observed on Ripple map provide useful ablation targets in
patients with persistent
AF . -
pubmed
METHODS AND RESULTS : Consecutive
patients underwent the first - time ablation of persistent
AF ( n = 162 ) using a standard stepwise ( n = 105 ) or a Ripple map guided approach ( n = 57 ) . -
pubmed
Acute termination of
AF was observed in 91.2 % of the Ripple - guided
patients vs 52.4 % in the stepwise approach , P & lt ; .0001 . -
pubmed
Following a single ablation procedure , after 18 months 98.2 % of Ripple map guided
patients were free of
AF , compared with 81.4 % of standard stepwise ablation ( P = .005 ) . -
pubmed
The rate of
myocardial infarction was lower ( 1.1 % vs 2.4 % ) and ventilator use for > 48 hours was less frequent ( 0.4 % vs 2.6 % ) for LPMAC
patients , though statistical significance was not reached . -
pubmed
HCMV seropositivity is associated with specific proinflammatory immune phenotype in women with
implantation failure . -
pubmed
HCMV coevolved with
humans for millions of years and is now one of the most widespread
infections worldwide . -
pubmed
Tube dysfunctions initiated 244 reinsertion / placement studies in 107
patients , 20 jejunostomy tube - related readmissions , and 78 phone calls to providers for
tube dysfunction . -
pubmed
We present a case of disseminated
varicella infection in a newly diagnosed
human immunodeficiency virus (
HIV ) patient causing acute
pancreatitis at initial disease presentation and subsequently leading to
multi organ dysfunction . -
pubmed
The
patient had no other risk factors for
pancreatitis . -
pubmed
Changes in
Clozapine Bioavailability in a Percutaneous Endoscopic Gastrostomy - Fed
Patient With Treatment - Resistant
Schizophrenia . -
pubmed
Methods : This is a prospective , open - label study ;
patients with moderate to severe evaporative
DE owing to
MGD were consecutively enrolled and underwent two IPL treatment sessions at 3 - week intervals . -
pubmed
Results : A total of 128 eyes of 64
patients ( 39
women , 25
men ; mean age 36.09 + - 11.13 years ) with moderate to severe
DE owing to MGD consecutively received IPL treatment at days 1 and 21 . -
pubmed
Conclusions : IPL treatment reduced the severity of DE symptoms and improved the overall tear film stability in
patients with moderate to severe evaporative
DE owing to
MGD . -
pubmed
In addition , visual complaints experienced by
DE patients secondary to
MGD significantly decreased . -
pubmed
BACKGROUND : Liquid biopsy is a novel approach for
cancer diagnosis , the value of which in
human gastrointestinal ( GI ) cancer has been confirmed by the previous studies . -
pubmed
This article summarized the recent advances in liquid biopsy with a focus on novel technologies and the use of it in the screening , monitoring , and treatment of
human GI cancer . -
pubmed
CONTENT : The concept of liquid biopsy was first used to define the detection of circulating
tumor cells ( CTCs ) in
cancer patients , and has been expanded to other biomarkers in blood and body fluids , such as circulating
tumor DNA ( ctDNA ) , extracellular vesicles ( EVs ) and circulating
tumor RNA . -
pubmed
Material and methods : Data from 138
patients with
rectal cancer ( I - III WHO ) , who were radically operated on in the period 2001 - 2004 in Bydgoszcz Oncology Centre were analysed . -
pubmed
Results : Among all
patients ( n = 138 ) and
patients following sRT ( n = 84 ) 7.4% ... 5.9 % local
recurrence and 24% ... 29 % distant
metastases were observed in 5 - year follow - up . -
pubmed
PURPOSE : The TWIST ( Testicular Work - up for
Ischemia and Suspected Torsion ) score was developed to allow for expedited diagnosis of
testicular torsion (
TT ) in
children based on clinical variables :
edema ( 2 points ) ,
hard mass ( 2 ) , absent cremasteric reflex ( 1 ) ,
high - riding testis ( 1 ) and
nausea /
vomiting ( 1 ) . -
pubmed
Patients with previous scrotal pathology or
trauma were excluded . -
pubmed
RESULTS : Of 68
patients , 34 had
TT ( 50 % ) . -
pubmed
Fifteen
patients had a score of 3 - 4 , among which seven had
TT . -
pubmed
Characterization and Exploration of Potential Neuroprotective Peptides in
Walnut (
Juglans regia ) Protein Hydrolysate against Cholinergic System Damage and Oxidative Stress in
Scopolamine - Induced
Cognitive and Memory Impairment Mice and
Zebrafish . -
pubmed
The purpose of this study was to determine the neuroprotective effect and mechanism of
walnut protein hydrolysates ( WPH ) against
memory deficits induced by
scopolamine in
mice and further to validate the potent neuroprotective peptides identified by integrated approaches of in silico analysis and peptidomics in
scopolamine - induced
zebrafish . -
pubmed
Rubber solvent was tested for its ability to induce
chromosome aberrations and sister - chromatid exchanges in
human whole blood cultures . -
pubmed
A lipid - free preparation containing 0.076 %
dexamethasone-21 - sodium - m - sulfobenzoate ( corresponding to 0.05 %
dexamethasone ) has been applied to the right side of the back and the same vehicle without the agent to the left side of the back of 16 male
subjects without any
skin diseases . -
pubmed
Experiments were carried out to assess the reduction rate of two salmonella
strains (
S. - pubmed
Malignant salivary gland neoplasms in
children are rare , most common being
mucoepidermoid carcinoma ,
adenoid cystic carcinoma ,
acinic cell carcinoma and
adenocarcinoma . -
pubmed
Most
germ - cell neoplasms of head and neck in
children are
teratomas . -
pubmed
The authors report a case of
endodermal sinus tumor (
EST ) of the parotid gland in a 2 - year - old
girl , which recurred after chemotherapy . -
pubmed
PATIENTS : Thirty
infertility patients . -
pubmed
U937 cells are established
human monoblast cell line originally isolated from a
patient with
diffuse histiocytic lymphoma . -
pubmed
Patients who had undergone bilateral neck dissection were injected on the
tumor side . -
pubmed
[ The prediction of the need for postoperative mechanical ventilation in
patients with
myasthenia gravis undergoing transsternal thymectomy ] . -
pubmed
During a sixteen - year period , 51
patients with
myasthenia gravis underwent trans - sternal thymectomy including extended resection of the adipose tissue around thymus . -
pubmed
These service
dogs were included in two different work
strain groups ( patrol
dogs and searching
dogs ) . -
pubmed
Other components of acid - base balance in blood do not show such variations ( patrol and searching
dogs ) and these components justify that the adaptation of organism to the given
strain gained suitable stabilisation . -
pubmed
For studying the psychical and physical
strain in service
dogs it is recommended to include pH and pCO2 in the tests . -
pubmed
During total hip replacement for 8
patients with
hip joint osteoarthritis specimens of femoral articular cartilages of 3 types of involvement were taken , i.e. -
pubmed
Effect of
diltiazem on 2,4 - D - induced
myotonia in
rats . -
pubmed
In
rat diaphragm , exposed to 2.5 mM
2,4 - D in a tissue bath ,
myotonia was quantified by documenting the contraction time in response to direct stimulation with supramaximal electric stimuli . -
pubmed
In vitro lipid - mobilizing activities of
morphine ( MO ) and dynorphin-(1 - 10 )
amide (
DYA ) were compared using adipocytes of young adult
rats (
body weight 170 - 200 g , age 50 - 60 days , diameter of adipocytes 54 + /- 1.12 microns ) and of 20 - month - old
rats (
body weight 500 - 690 g , diameter of adipocytes 99.5 + /- 3.0 microns ) . -
pubmed
Increased release of atrial natriuretic polypeptides in
rats with
DOCA - salt
hypertension . -
pubmed
Thus , it seems likely that the release of ANPs is increased in response to expansion of extracellular fluid volume or elevation of blood pressure , modifying the development of
hypertension in
DOCA - salt
rats . -
pubmed
Resistance of
seizures to anti -
epileptic therapy may be due to
patient error , or to physician diagnostic and/or treatment error , rather than being truly intractable
epilepsy . -
pubmed
Repeated assessment of
patients with
refractory epilepsy is important , as causative or provocative factors may remain latent for long periods . -
pubmed
Two - thirds of the
patients with
Friedreich ' s ataxia showed moderate
cerebellar atrophy and an increase in the surface area of the fourth ventricle . -
pubmed
Severe
cerebellar atrophy and
enlargement of the cerebellopontine angle cistern was seen in
patients with olivopontocerebellar (
OPC )
atrophy and
idiopathic cortical cerebellar atrophy . -
pubmed
Diffuse proliferative
glomerulonephritis was found in 60 % of
patients with
acute nephritic syndrome . -
pubmed
Fifteen
children with
acute renal failure were biopsied , 2 of whom had
haemorrhagic fever . -
pubmed
To investigate the role of " behavioral inhibition to the unfamiliar " as an early temperamental characteristic of
children at risk for adult
panic disorder and
agoraphobia (
PDAG ) , we compared children of parents with
PDAG with those from psychiatric comparison groups . -
pubmed
With a median follow - up of 16 months ( range , 6 - 35 ) , only 11
patients ( 37 % ) have had disease
recurrence and eight ( 27 % ) have died . -
pubmed
A
luminol - enhanced chemiluminescence assay was used to measure light elaborated by peripheral blood polymorphonuclear leukocytes ( PMNs ) and by pulmonary alveolar macrophages ( PAMs ) from 14 healthy , normal subjects and 16
patients with
sarcoidosis . -
pubmed
Resting peripheral blood PMNs ( incubated only in medium ) from
patients with
sarcoidosis generated substantially more chemiluminescence than PMNs from normal control subjects ( p = 0.002 ) . -
pubmed
With zymosan stimulation , greater chemiluminescence was produced by PMNs from untreated
patients with
sarcoidosis than from normal subjects ( p less than 0.05 ) , whereas no differences were noted with latex stimulation . -
pubmed
Chemiluminescence for resting PAMs was not different between normal subjects and
patients with
sarcoidosis . -
pubmed
Increased chemiluminescence by PMNs and PAMs from
patients with
sarcoidosis may reflect phagocyte activation in the disease process . -
pubmed
Serratia marcescens infection : a growing threat . -
pubmed
[ Correction of
metabolic acidosis in
patients with
inflammatory diseases of the biliary tract ] . -
pubmed
Removal of glomerular immune complex deposits by excess antigen in chronic
mouse model of
immune complex disease . -
pubmed
3H - HpD was injected intravenously at a 10 mg / kg dose into 30
Sprague - Dawley rats ( Group A ) without
tumors in order to clarify method . -
pubmed
Separately ,
3H - HpD of like dosage was injected into 20
Fischer-344 rats ( Group B ) , 5 control and 15 with a
9L gliosarcoma implanted in the left anterior cerebral cortex . -
pubmed
The
tumor area , peritumoral margin , and distant uninvolved areas of the
Fischer-344 9L rats were likewise assayed . -
pubmed
An assay was performed with 5 Fischer-344 9L
brain tumor rats ( Group C ) , sacrificed at 24 hours . -
pubmed
Preliminary clinic testings show that
imuthiol restores T cell activities and regulates the ratio among T cell subsets in
cancer patients , without untoward side effects . -
pubmed
D - Galactosamine liver injury : absorption of endotoxin and protective effect of small bowel and colon resection in
rabbits . -
pubmed
D - Galactosamine is an
amino sugar with unique
hepatotoxic properties in
animals . -
pubmed
Although the mechanism of
liver injury by
galactosamine remains controversial , a role for
bacterial endotoxin has been suggested . -
pubmed
[ Effect of the pesticide
carbaryl (
sevin ) on the course of experimental
Erysipelothrix rhusiopathiae infection in
rats ] . -
pubmed
It was found that
rats that were given
carbaril for a long time in minimum amounts and were then subjected to
infection developed a characteristic clinical picture and showed a high mortality rate ( nearly twice as high as that with the control animals ) . -
pubmed
Aggressive pharmacotherapy for the treatment of
patients with severe
status asthmaticus includes
theophylline and beta - adrenergic agonists such as
isoproterenol . -
pubmed
Penetration of
cefoxitin into cerebrospinal fluid of infants and
children with
bacterial meningitis . -
pubmed
Three consecutive doses of 75 mg of
cefoxitin per kg were given intravenously every 6 h ( 225 mg / kg ) , in addition to
penicillin or
ampicillin , to 24
patients on days 4 and 5 and 9 and 10 of therapy for
meningitis . -
pubmed
Eighteen fetal
lambs were divided into three experimental groups :
diaphragmatic hernia (
DH ) , DH and simultaneous tracheal ligation ( DH / TL ) , and sham - operated controls ( C ) . -
pubmed
Prolonged
hypoxia in the adult
rat causes a decline in endothelium - derived
nitric oxide (
NO ) production in the pulmonary circulation . -
pubmed
The pharmacokinetics of
itraconazole oral solution were measured in seven
patients receiving chemotherapy followed by autologous bone marrow transplantation for
leukaemia or
lymphoma . -
pubmed
Thus serum concentrations of
itraconazole suitable for antifungal prophylaxis can be attained in
neutropenic patients , with the administration of an oral solution in a dosage of 5 mg / kg as either an od or bd schedule , following pre - autograft high - dose cytotoxic chemotherapy . -
pubmed
A daily diet of meat including
beef ,
chicken , and pork had a close relationship with cedar
pollinosis . -
pubmed
Comparative renal hemodynamic effects of
lisinopril ,
verapamil , and
amlodipine in
patients with
chronic renal failure . -
pubmed
We investigated the effects of
lisinopril ,
verapamil , and
amlodipine in 26
hypertensive patients with
chronic renal disease of varying etiologies . -
pubmed
Patients who had a significant lowering of blood pressure in response to
lisinopril and
verapamil had favorable renal hemodynamic responses as well --
GFR remained stable , RBF was stable or increased , and filtration fraction , renal vascular resistance , and
proteinuria tended to decrease . -
pubmed
Our results demonstrate a heterogeneity in response to antihypertensive agents in
patients with
renal disease . -
pubmed
A 15 - year - old
boy with
thalassaemia major treated with
desferrioxamine , experienced
fever associated with
digestive disorders . -
pubmed
Systemic
yersiniosis was further confirmed by the finding of antibodies to
Yersinia enterocolitica O5 . -
pubmed
Evaluation of serum - associated
embryotoxicity in
women with
reproductive disorders . -
pubmed
RESULTS : After 72 hr , blastocyst spreading was significantly different depending on whether cultured in sera from
women with unexplained
infertility ,
anovulatory infertility ,
diethylstilbesterol exposure or controls . -
pubmed
Neither sera from women with
mechanical infertility ( 14 ) nor sera from
women with
endometriosis ( 8) affected blastocyst growth in culture . -
pubmed
It can be inferred that the inhibitory effect of sera from
women with certain types of
infertility might be due to damage to the cytoskeleton . -
pubmed
In an attempt to reestablish the dimorphic process in
strains of
Paracoccidioides brasiliensis in the transition phase ( Y reversible M ) and to reisolate them , five
strains in the transitional phase due to the long time of preservation under mineral oil and two
strains in the
yeast - like phase were inoculated into male
albino rats . -
pubmed
The aim of this paper is to focus on our previous experience with the treatment of Group 3 and 4
neuroblastoma patients and on the therapeutic use of
[ 131I ] MIBG , to better define the role of this radioactive drug in the treatment of
neuroblastoma (
NB ) . -
pubmed
[ 131I ] MIBG administered in advanced stage 4
patients induced a response in 50 % of the cases ( 2 complete response [ CR ] , 13 PR and 2 MR out of 34
children ) and 8
children treated for residual primary ( 4 cases ) or residual
bone metastases ( 4 cases ) are long term survivors . -
pubmed
We conclude that
[ 131I ] MIBG is the treatment of choice in Group 3
patient with a residual primary
tumor and could contribute to consolidate the response obtained in Group 4
patients . -
pubmed
A study was therefore conducted on 40
women aged 20 - 35 , with
iron - deficiency anaemia during or immediately after pregnancy all of whom presented Hb & lt ; 10 gr / dl , Ht & lt ; 33 % and serum
iron & lt ; 60 micrograms / dl . -
pubmed
All
women with pregnancy - related pathological conditions , pre - existing on concomitant disease (
Type I diabetes ,
heart diseases etc . ) -
pubmed
BACKGROUND : Assessment of language organization is crucial in
patients considered for
epilepsy surgery . -
pubmed
We used fMRI , to assess language dominance in
children with
partial epilepsy . -
pubmed
fMRI demonstrated left dominance in three additional
children , and right dominance in one with early onset of
left temporal epilepsy . -
pubmed
Sixty
patients with
PSVT were randomized to have a bolus of 0.3 mg / Kg of
diltiazem or 75 micrograms / Kg of
verapamil . -
pubmed
In relation with the drug safety , only 5
patients showed
hypotension , without clinical relevance , in the
diltiazem group . -
pubmed
With
verapamil one
patient had a
transitory ischemic attack after recover sinus rythm . -
pubmed
3 )
Diltiazem was effective for slowing the ventricular rate in 83 % of the
patients with
AF who did not revert to
sinus rythm . -
pubmed
Noninvasive measurement of shortening in the fiber and cross - fiber directions in the normal
human left ventricle and in
idiopathic dilated cardiomyopathy . -
pubmed
The purpose of this study was to estimate the extent of fiber and cross - fiber shortening in the normal
human left ventricle and in
patients with
idiopathic dilated cardiomyopathy (
IDC ) . -
pubmed
METHODS AND RESULTS : Ten normal
subjects and nine
patients with
IDC were imaged with magnetic resonance tissue tagging . -
pubmed
Anatomic fiber angles were not different between normal subjects and
IDC patients . -
pubmed
Epicardial fiber
strain was -0.14+/-0.01 in normal subjects and -0.08+/-0.01 in
IDC patients ( P<.0001 versus normal subjects ) . -
pubmed
Endocardial fiber
strain was -0.16+/-0.01 in normal subjects and -0.09+/-0.01 in
IDC patients ( P<.0001 ) , and endocardial cross - fiber
strain was -0.26+/-0.01 in normal subjects and -0.15+/-0.01 in
IDC patients ( P<.0001 ) . -
pubmed
Antibiotic - loaded
hydroxyapatite blocks in the treatment of experimental
osteomyelitis in
rats . -
pubmed
In this study , implantation of HABs loaded with the
aminoglycoside antibiotic ,
arbekacin , were tested in established
Staphylococcus aureus osteomyelitis in the proximal tibia of
rats after debridement of the marrow cavity . -
pubmed
Microvessel density was found to be associated with the overall survival in
women with invasive
carcinoma ( P & lt ; 0.01 ) . -
pubmed
There was a significant correlation of microvessel density ( P & lt ; 0.05 ) with
relapse - free survival in
patients with regional lymph node
metastasis . -
pubmed
A Cox stepwise regression analysis revealed microvessel density , together with depth of invasion , regional lymph node status , and vascular invasion , to be a strong independent prognostic indicator for overall survival in
patients with clinical stage IB
cervical carcinoma . -
pubmed
A
venous occlusion ( VO ) test was performed preoperatively in 82
patients undergoing revascularization procedures . -
pubmed
Patients recovered rapidly with minimal to no
bruising ,
scarring , or
pain . -
pubmed
We quantified overall
obesity by the
body mass index (
BMI ) and used a previously validated magnetic resonance imaging ( MRI ) method to quantify abdominal fat in 63 healthy nondiabetic
individuals aged 22 to 83 years . -
pubmed
Autologous PBPCT in a
patient with
lymphoma and
Sjogren ' s syndrome : complete remission of
lymphoma without control of the
autoimmune disease . -
pubmed
A
patient with primary
Sjogren ' s syndrome developed massive gland enlargement and was diagnosed a
MALT - type lymphoma stage IIA . -
pubmed
After initial radiotherapy the
patient relapsed with high grade
immunoblastic lymphoma . -
pubmed
However , subsequent to standard chemotherapy the
patient experienced an exacerbation of
arthralgia and
vasculitis while his
lymphoma remained in partial remission . -
pubmed
Steroid treatment improved this , but the
patient remained
steroid - dependent and later died from therapy - resistant
Pneumocystis carinii pneumonia while the
lymphoma remained in complete remission . -
pubmed
In this
patient with
systemic Sjogren ' s disease , PBPCT completely controlled the aggressive
lymphoma but was not permanently effective for the
autoimmune disease . -
pubmed
Bone cyst causing acute
lameness in a
dog . -
pubmed
Totally implanted venous access ports are excellent devices for delivering chemotherapeutic agents and prolonged intravenous infusions in
patients with
cancer . -
pubmed
The antibacterial action of the oil extract obtained from
tomato pulp has been studied with the use of museum strains
Escherichia coli ATCC 25922 ,
Staphylococcus aureus ATCC 5638 - P and
Candida albicans ATCC 885 - 653 , recommended for the determination of the antibacterial activity of medicinal preparations ( State Pharmacopoeia , edition XI ) , as well as
Enterobacter ,
Streptococcus ,
Staphylococcus ,
Klebsiella and
Escherichia clinical
strains . -
pubmed
Effectiveness of the analogue of natural
Schisandrin C (
HpPro ) in treatment of
liver diseases : an experience in Indonesian
patients . -
pubmed
OBJECTIVE : To determine the effect of
dimethyl-4,4 '- dimethoxy-5,6 , 5 ' , 6 - dimethylene dioxybiphenyl-2,2 '- dicarboxylate (
HpPro ) on
patients with acute and chronic
liver diseases . -
pubmed
CONCLUSION : Treatment with
HpPro is effective to reduce
liver impairment in acute and chronic
liver diseases on Indonesian
patients . -
pubmed
We examined the mechanisms responsible for
myocardial ischemia - reperfusion (
MI - R ) injury in a well - characterized
animal model of
type II diabetes mellitus . -
pubmed
Diabetic ( db / db )
mice and their littermate nondiabetic controls were subjected to 30 min of left anterior descending
coronary artery occlusion and 2 h of reperfusion . -
pubmed
Diabetic and nondiabetic
mice experienced similar - sized areas at risk per left ventricle : 50.4 + /- 2.0 and 53.4 + /- 4.1 % , respectively . -
pubmed
However ,
myocardial necrosis ( percentage of area at risk ) was significantly greater ( P & lt ; 0.001 ) in
diabetic than in nondiabetic
animals : 56.3 + /- 2.8 and 27.2 + /- 3.1 % , respectively . -
pubmed
The domestic
cat is an outbred species with many identified analogues of
human genetic diseases . -
pubmed
In 1994 , the US Public Health Service published guidelines for the use of
zidovudine to decrease the risk of perinatal transmission of
human immunodeficiency virus (
HIV ) . -
pubmed
Widespread incorporation of these guidelines into clinical practice has resulted in a dramatic decrease in the rate of perinatal
HIV transmission and has contributed to more than a 75 % decrease in reported cases of pediatric
acquired immunodeficiency syndrome (
AIDS ) since 1992 . -
pubmed
Full implementation of recommendations for universal , routine prenatal
HIV testing and evaluation of missed prevention opportunities will be critical to further decrease the incidence of pediatric
HIV infection in the United States . -
pubmed
In this strategy , the phenotype of the
pancreatitis - affected pancreas is established by characterization of a large number of its transcripts using a high - density
mouse cDNA microarray . -
pubmed
Hypotensive effects of
captopril on physical properties of the arterial system in young and adult
rats . -
pubmed
No age dependence of vascular response and reflex
tachycardia to
captopril has been found in
rats between 4 and 12 months . -
pubmed
CONCLUSIONS : Our results show observe the safety of glucocorticoid therapy among pregnant
women with
hypertensive disorders related to the possible raising of the blood pressure levels . -
pubmed
CONCLUSIONS : Feasibility of using transgenic
mice carrying photoactive reporter genes for studying cellular process of laser - inflicted
wound repair in a noninvasive , in vivo manner was shown . -
pubmed
METHODS : Two hundred forty - eight study subjects were allocated to two study groups and received either two doses of the combined
hepatitis A and B vaccine ( 68 % of subjects ) or the corresponding monovalent
hepatitis A and
hepatitis B vaccines ( 32 % of subjects ) concomitantly in opposite arms . -
pubmed
A double blind study was conducted to evaluate the effectiveness of the generation of magnetic fields on
edema and on
pain in
patients submitted to surgery for bilateral
hallux valgus . -
pubmed
Also , for 18 months we compared 42
obese patients treated only with 1000 kcal / day diet ( group A ) with 31
obese patients subjected to BIB for 4 months + 1000 kcal / day diet ( group B ) . -
pubmed
Weight loss was greater in male
patients . -
pubmed
CONCLUSION : The best indications for BIB were : morbidly obese opatients (
BMI & gt ; 40 ) and super - obese
patients (
BMI & gt ; 50 ) in preparation for bariatric operations ;
obese patients with
BMI 35 - 40 with co - morbilities in preparation for bariatric surgery ;
obese patients with
BMI 30 - 35 with a
chronic disease otherwise unresolved ; patients with
BMI & lt ; 30 only in a multidisciplinary approach . -
pubmed
Twenty multidrug - resistant
vancomycin - resistant
Enterococcus faecium strains of the VanA phenotype were isolated over a 1 year period from five patients in the intensive care unit at the University Hospital of Antalya , Turkey . -
pubmed
OBJECTIVES : The Sensio study objectives were to assess the outcome of neuropsychiatric adverse reactions (
NPAR ) that develop after initiation of
efavirenz (
EFV ) therapy , to ascertain the late
NPAR after a 3 - month treatment period , to evaluate the impact of NPAR on
patients ' quality of life ( QoL ) in a real - life population . -
pubmed
METHODS : During a 6 - month period , consecutive
HIV - infected adult
outpatients receiving an ongoing
EFV therapy for at least 3 months were asked to fill in a specifically designed self - administered questionnaire addressing
sleep disturbances , behavioural changes ,
mood disturbances ,
anxiety ,
cognitive disorders ,
hallucinations ,
dizziness and the general impact on patients ' QoL. -
pubmed
RESULTS : Among the 302
patients , 134 ( 44.37 % ) were below the age of 40 years ( juvenile - onset
thrombosis ) , mean age being 35.3 years . -
pubmed
PURPOSE : To identify the characteristics of adult
patients who develop acute concomitant
esotropia of adulthood . -
pubmed
INTERVENTION : The charts of all
adults with acute - onset concomitant
esotropia who were examined at our institute between 1990 and 1997 were reviewed , and those who had developed the
syndrome when they were older than the age of 16 years were included in this study . -
pubmed
Nine of the 10
patients were
myopic . -
pubmed
CONCLUSIONS : In a well - defined group of adult
patients with acute - onset concomitant
esotropia , almost all were
myopic , and all regained normal stereopsis after surgery . -
pubmed
Propylene oxide ( PO ) is a high - volume chemical intermediate that causes a low incidence of
nasal tumors in
rodents exposed to high concentrations ( & gt ; or = 300 p.p.m . ) -
pubmed
PURPOSE The purpose of the study was to determine the variables associated with
postoperative pain and the clinical response of
patients with uncomplicated
hemorrhoidal disease treated with stapled rectal mucosectomy in the medium term . -
pubmed
Effect of chemical protection and bone marrow treatment on
radiation injury in
mice . -
pubmed
A new skeletal muscle relaxant ,
methocarbamol , was used in the treatment of 38
patients with a variety of severe
neurological disorders and skeletal
muscle spasm states . -
pubmed
Mild side effects such as
drowsiness were observed in five
patients , mild
weakness in three
patients and excessive perspiration in one . -
pubmed
In two of the five
patients who complained of
drowsiness , it disappeared upon reduction of dosage and did not reappear when original dosage was reinstituted . -
pubmed
[ Effectiveness of combined balneoclimatic treatment of
patients with
psoriasis at Sochi - Matsesta health resort ] . -
pubmed
Combination of
femoral fracture treatment and corrective osteotomy in a
child with
osteogenesis imperfecta . -
pubmed
We report a case of a 3 - year - old
child with
osteogenesis imperfecta type I who suffered an undisplaced
femoral shaft fracture in the presence of a preexisting 32 degrees femoral antecurvation . -
pubmed
Liver - directed
adenoviral gene transfer in
murine succinate semialdehyde dehydrogenase deficiency . -
pubmed
In
ulcerative colitis ,
steroids are rarely needed as
5 - aminosalicylates are effective in the majority of
patients . -
pubmed
In
Crohn ' s disease ,
steroids are more often used ; however , in population - based studies , less than 50 % of
patients have been treated with
steroids , as there are alternative treatments available for the large group of
patients with mild to moderate activity . -
pubmed
OBJECTIVE : Despite similar disease patterns and treatment , there is great variation in clinical outcome between
venous ulcer patients . -
pubmed
METHODS : Consecutive
patients assessed by a specialist nurse - led
leg ulcer service between January 1998 and July 2003 with an ABPI>0.85 were included in this study . -
pubmed
Patient age ( p & lt;0.001 , HR per year 0.989 , 95 % CI 0.984 - 0.995 ) and
ulcer chronicity ( p = 0.019 , HR per month 0.996 , 95 % CI 0.993 - 0.999 ) were independent risk factors for delayed
ulcer healing . -
pubmed
CONCLUSIONS : Elderly
patients with longstanding
ulcers should be targeted for further research and may benefit from adjunctive treatments to improve clinical outcomes . -
pubmed
Patients not treated with superficial venous surgery were at increased risk of
leg ulcer recurrence . -
pubmed
Regular exercise is important for
patients with
multiple sclerosis (
MS ) to maintain their functional ability and general health . -
pubmed
PPT occurs in 50 % of
women with high titre of these antibodies . -
pubmed
Evaluation of the reticulocyte micronucleus assay in
patients treated with
radioiodine for
thyroid cancer . -
pubmed
In the present investigation , the utility and sensitivity of this method was studied in 44 young
patients from Belarus , who were treated with
131I for
thyroid cancer . -
pubmed
We identified 8
children with genetically determined
dyslipidemia : 2
children with homozygous and 6 with heterozygous
familial hypercholesterolemia . -
pubmed
Screening the progeny of young patients with
CHD or
familial hypercholesterolemia can identify
children at excessive risk for future
vascular disease . -
pubmed
Adrenalectomy and castration in the genetically
obese ( ob / ob )
mouse . -
pubmed
The present studies have tested the hypothesis that adrenalectomy could modify the phenotypic expression of
genetic obesity by examining the effects of adrenalectomy on the function of the gonadal system in lean and ob / ob
mice . -
pubmed
Adrenalectomy significantly slowed the
weight gain of
obese mice in comparison to sham - adrenalectomized controls . -
pubmed
These data indicate that adrenalectomy has no effect on the physiologic control of the reproductive system in genetically
obese mice , and are consistent with the hypothesis that the defect in the ob / ob
mouse is a modulator of
steroid action which over expresses glucocorticoid effects and under expresses gonadal
steroid effects . -
pubmed
During 2004 , 49 states and Puerto Rico reported 6,836 cases of
rabies in nonhuman animals and 8 cases in
human beings to the CDC , representing a 4.6 % decrease from the 7,170 cases in nonhuman animals and 3 cases in
human beings reported in 2003 . -
pubmed
Texas reported only 1 case of
rabies in a
dog that was infected with the
dog / coyote rabies virus variant and only 22 cases associated with
theTexas gray fox rabies virus variant ( compared with 61 cases in 2003 ) . -
pubmed
Cases of
rabies reported in
cats ,
dogs ,
horses and
mules , and
sheep and
goats decreased 12.5 % , 19.7 % , 31.8 % , and 16.7 % , respectively , whereas cases reported in
cattle increased 174 % . -
pubmed
Among the 8 cases of
rabies in
human beings , 1 person from Oklahoma and 3 from Texas died following receipt of infected organs and tissues from an Arkansas donor . -
pubmed
METHODS : A decision - analytic model of the epidemiology and treatment of
GHD in
children was developed . -
pubmed
In our 18 - year - old male
patient , there were
atrophic plaques unilaterally located on the trunk and arm , and white discoloration on all finger nails . -
pubmed
Streptococcus pneumoniae is among the most common pathogens associated with
chronic otitis media with
effusion , which has been hypothesized to be a
biofilm disease . -
pubmed
Medication adherence in
glaucoma : approaches for optimizing
patient compliance . -
pubmed
Nitroproteins from a
human pituitary adenoma tissue discovered with a
nitrotyrosine affinity column and tandem mass spectrometry . -
pubmed
The aim of this study was to characterize endogenous nitroproteins , and those proteins that interact with nitroproteins , in a
human pituitary nonfunctional
adenoma so as to clarify the role of protein nitration in
adenomas . -
pubmed
A
nitrotyrosine affinity column ( NTAC ) was used to preferentially enrich and isolate endogenous nitroproteins and nitroprotein - protein complexes from a tissue homogenate that was prepared from a
human pituitary nonfunctional
pituitary adenoma . -
pubmed
Those data indicate that protein nitration might be an important molecular event in the formation of a
human pituitary nonfunctional
adenoma . -
pubmed
Prevalence of
aspirin resistance in
patients with an evolving
acute myocardial infarction . -
pubmed
OBJECTIVE : To study the prevalence and importance of
aspirin resistance in
patients with an evolving
acute myocardial infarction (
AMI ) by use of the Platelet Function Analyzer-100 . -
pubmed
We hypothesized that the prevalence of
aspirin resistance in
patients with
AMI was twice the prevalence in
patients without
AMI . -
pubmed
METHODS : We included 298 consecutive
patients with known
cardiovascular disease who were admitted to hospital with symptoms suggestive of an
AMI . -
pubmed
The prevalence of
aspirin resistance was significantly higher in
patients with
AMI as compared to patients without ( 36 % versus 20 % , OR 2.26 , CI 95 % 1.19 - 4.22 , p=0.0058 ) . -
pubmed
CONCLUSIONS :
Aspirin resistance is present in almost one fourth of
patients admitted to hospital with symptoms suggestive of an
AMI , and
aspirin resistance is significantly associated with the diagnosis of a definite
AMI . -
pubmed
Coenzyme Q10 deficiency has been observed in
patients with
congestive heart failure ,
angina pectoris ,
coronary artery disease ,
cardiomyopathy ,
hypertension ,
mitral valve prolapse . -
pubmed
Ubiquinone is the introduction of the metabolic drugs and may be recommended to
patients with
cardiovascular pathologies as an adjunct to conventional treatment . -
pubmed
Assessment for additional
spinal trauma in
patients with
cervical spine injury . -
pubmed
This analysis includes 129 CSI
patients ( 1.3 % of
trauma admissions ) . -
pubmed
Cervical spine radiographs diagnosed
injuries in 71 per cent of CSI
patients . -
pubmed
Injuries involved two adjoining vertebrae in 38 patients and three or more adjoining vertebrae in 7
patients . -
pubmed
Injuries were isolated in 45 per cent and were multilevel in the remaining CSI
patients . -
pubmed
Assessment of the entire spinal column should be done in
patients with
CSI . -
pubmed
BACKGROUND :
Anisakis simplex is a fish parasite that can cause
allergy in
humans . -
pubmed
Omeprazole before endoscopy in
patients with
gastrointestinal bleeding . -
pubmed
METHODS : Consecutive
patients admitted with upper
gastrointestinal bleeding underwent stabilization and were then randomly assigned to receive either
omeprazole or placebo ( each as an 80 - mg intravenous bolus followed by an 8 - mg infusion per hour ) before endoscopy the next morning . -
pubmed
There were no significant differences between the
omeprazole group and the placebo group in the mean amount of blood transfused ( 1.54 and 1.88 units , respectively ; P=0.12 ) or the number of
patients who had recurrent
bleeding ( 11 and 8 , P=0.49 ) , who underwent emergency surgery ( 3 and 4 , P=1.00 ) , or who died within 30 days ( 8 and 7 , P=0.78 ) . -
pubmed
On endoscopy , fewer
patients in the
omeprazole group had actively
bleeding ulcers ( 12 of 187 , vs. 28 of 190 in the placebo group ; P=0.01 ) and more
omeprazole - treated
patients had
ulcers with clean bases ( 120 vs. 90 , P=0.001 ) . -
pubmed
The effect of dietary high - amylose
corn starch ( HACS ) of varying dietary fiber ( DF ) content on plasma
cholesterol was examined in ovariectomized ( OVX )
rats . -
pubmed
PARTICIPANTS : One hundred consecutive
patients with
cough , ages 1 to 90 . -
pubmed
STUDY DESIGN :
Patients who underwent partial hepatectomy between 1997 and 2001 , with complete preoperative radiographic imaging and postoperative pathologic assessment of
steatosis , were retrospectively analyzed . -
pubmed
Furthermore , specific technologies are now available to screen
animal model or
human blood samples for novel , improved markers of
chronic disease states , such as
atherosclerosis or for earlier indicators of acute myocardial stress , including
ischemia /
reperfusion injury and
heart failure . -
pubmed
Among special subgroup of
patients , in which acute
pain exacerbation ,
mechanical block or early
OA , utilizing arthroscopic techniques revealed satisfactory results . -
pubmed
METHODS : Male
Wistar rats were randomly divided into three groups : control group ;
fibrosis group , which received the solution of
CCl4 in oil twice a week for 5 weeks ; and hepatectomy group , which underwent 70 % hepatectomy . -
pubmed
[ Surgical treatment of 154
patients with non - traumatic acute
lower limb ischemia ] . -
pubmed
METHODS : The clinical data of 154 acute
lower limb ischemia patients surgically treated from July 1999 to December 2007 were retrospectively analyzed . -
pubmed
The
patients were divided into two groups according to pathogenesis :
acute arterial embolism group ( 99 cases ) and acute arterial
thrombosis group ( 55 cases ) . -
pubmed
RESULTS : Female experienced acute
arterial embolism more often than
man ( 60.6 % vs 39.4 % , P & lt ; 0.05 ) , and more acute arterial
thrombosis occurred in
man ( 72.7 % vs 27.3 % , P & lt ; 0.05 ) . -
pubmed
PATIENTS AND METHODS : In the first part , sera from 24
SSc patients ( 12 with
pulmonary arterial hypertension (
PAH ) and 12 without ) and 36 idiopathic
PAH patients , tested in pooled sera for groups of three , were compared with a sera pool from 14 healthy controls ( HC ) . -
pubmed
An unusual case of hospital - acquired
infection :
Legionella Longbeachae . -
pubmed
METHOD : Between 1992 and 2000 a consecutive series of 80
patients with a high transsphincteric
fistula of cryptoglandular origin underwent TAFR . -
pubmed
The medical records revealed that only one of these
patients presented with a recurrent
fistula after 28 months . -
pubmed
The other 53
patients were sent a questionnaire in 2006 aimed to determine whether they had any complaints or signs of a recurrent
fistula . -
pubmed
None of these
patients reported any complaints or signs of a recurrent
fistula . -
pubmed
CONCLUSION : At a median time interval of 3.6 months
fistula healing was observed in 54
patients ( 68 % ) . -
pubmed
Only one
patient ( 2 % ) encountered a
recurrence . -
pubmed
Pharmacomechanical thrombectomy for iliofemoral
deep vein thrombosis : an alternative in
patients with contraindications to thrombolysis . -
pubmed
OBJECTIVE : Venous lysis is usually reserved for symptomatic
patients with acute
deep vein thrombosis (
DVT ) and low risk for
bleeding . -
pubmed
METHODS : A retrospective review of all
patients with symptomatic
DVT treated between 2007 and 2008 with PMT was performed . -
pubmed
There were no major systemic
bleeding complications , but access site
hematoma occurred in two
patients and worsening of pre - existing rectus sheath
hematoma requiring transfusion occurred in another two . -
pubmed
Limb salvage was maintained in 100 % of
patients who presented with
phlegmasia . -
pubmed
CONCLUSIONS : PMT can be safely and effectively used for subacute iliocaval and iliofemoral
DVT and in
patients with contraindications for lytic therapy , resulting in improved functional outcomes relative to their debilitated state before the procedure . -
pubmed
Influence of operative timing on prognosis of
patients with
acute subdural hematoma . -
pubmed
OBJECTIVE : To study the influence of operative timing on the prognosis of
patients with
acute subdural hematoma (
ASDH ) in order to provide theoretical basis for clinical treatment . -
pubmed
METHODS : The clinical data of 202
patients with
ASDH undergoing operations were collected , and the mortalities and functional survival rates were analyzed 2 , 4 , 6 , and 8 hours after
injury . -
pubmed
CONCLUSIONS : Operative timing has potential influences on the prognosis of
patients with
ASDH . -
pubmed
Their intravenous injection into
mice causes marked
hemoglobinuria ,
anemia , and
death . -
pubmed
There is evidence that this
anemia is not the only cause of
death of these
animals . -
pubmed
The sporadic reports on vaccine - induced
inflammatory myopathies include cases of
hepatitis B virus , bacillus Calmette - Guerin ,
tetanus ,
influenza ,
smallpox ,
polio ,
diphtheria ,
diphtheria - pertussis - tetanus , combination of
diphtheria with
scarlet fever and
diphtheria - pertussis - tetanus with
polio vaccines . -
pubmed
The objective of this study was to investigate the sleep architecture and the presence of
depression in
individuals with low endogenous
melatonin levels . -
pubmed
We propose that the combination of FUNC and FOUR scores will be a better prognostic indicator than either FUNC or FOUR score alone for S -
ICH patients . -
pubmed
METHODS : We conducted a retrospective chart review of all S -
ICH patients ( & gt;18 years of age ) from January 2008 to May 2010 . -
pubmed
CONCLUSIONS : The combination of the FUNC and the FOUR scoring system is a better prognostication indicator for S -
ICH patients than either FUNC or FOUR score . -
pubmed
BACKGROUND : The purpose of this study was to determine the effect of lymph node sampling and taking of blind biopsies as part of the surgical staging procedure for early
ovarian cancer on
disease - free survival ( DFS ) and overall survival ( OS ) in
patients who received no adjuvant chemotherapy . -
pubmed
METHODS : In the EORTC ACTION Trial , 448
patients with early ovarian
carcinoma were randomized between November 1990 and March 2000 - 224
patients to observation and 224 to adjuvant
platin - based chemotherapy . -
pubmed
Recurrences occurred in 11 ( 14.6 % ) of 75
patients in group A , 16 ( 34.8 % ) of 46
patients in group B , and 5 ( 35.7 % ) of 14 in group C. The 5 - year DFS in group A was 79 % versus 61 % and 64 % in groups B and C , respectively . -
pubmed
The objective of this pictorial essay is to highlight the key role of computed tomography scanning ( CT scan ) , particularly minimum intensity projection ( MinIP ) reformation , with regards to the diagnosis of
hypersensitivity pneumonitis (
HP ) and its contribution to
patients ' management . -
pubmed
Correlations in
brain atrophy changes between
rabbit brain and
human AD brain were found for frontal lobe and hippocampal regions . -
pubmed
In contrast , other regions such as midbrain , temporal lobe , and lateral ventricles were not correlated with
rabbit brain atrophy changes in the corresponding regions . -
pubmed
Among the loci targeted by pathogen - driven selection , we found an enrichment of genes associated to
autoimmune diseases , such as
celiac disease ,
type 1 diabetes , and
multiples sclerosis , which lends credence to the hypothesis that some susceptibility alleles for
autoimmune diseases may be maintained in
human population due to past selective processes . -
pubmed
Here , we used ' HLA - humanized '
mice to discern the potential relative contribution of DRB1 * 1501 and DQB1 * 0602 alleles to susceptibility to " humanized "
MS - like disease induced by
PLP , one of the most prominent and encephalitogenic target -
antigens implicated in
human MS . -
pubmed
RESULTS : The group comprised 51
patients with
HAP . -
pubmed
The most frequent bacterial pathogens were
strains of
Klebsiella pneumoniae ,
Pseudomonas aeruginosa ,
Burkholderia cepacia complex and
Escherichia coli , together accounting for 72 % . -
pubmed
Eighteen
patients died directly due to
HAP , an overall mortality rate of 35 % . -
pubmed
However , it does document the clinical impact of bacterial resistance on the survival or
death of
patients with
HAP . -
pubmed
Do
cervical cancer data justify
HPV vaccination in India ? -
pubmed
Although
HPV prevalence is higher in
cancer patients ( 93.3 % ) than healthy patients ( 7.0 % ) and
HPV types 16 and 18 are most prevalent in
cancer patients , population prevelance data are poor and studies highly variable in their findings . -
pubmed
In particular ,
mitochondrial dysfunction has long been implicated in the etiopathogenesis of
Parkinson ' s disease (
PD ) , based on the observation that mitochondrial toxins can cause
parkinsonism in
humans and
animal models . -
pubmed
Retrograde
aortic dissection at the proximal part of the aortic endovascular graft and a guidewire - induced iatrogenic
left ventricular pseudoaneurysm were presented in this
patient after the stent - grafting procedure . -
pubmed
BACKGROUND : Prognosis of localised
gastrointestinal stromal tumour (
GIST ) is heterogeneous , notably for
patients with AFIP intermediate or high risk of
relapse , who are candidates to adjuvant
imatinib . -
pubmed
We also analysed a data set from 28
patients with advanced
GIST treated with neo - adjuvant
imatinib . -
pubmed
BACKGROUND : Several experimental studies in
stroke patients suggest that mirror therapy and various virtual reality programs facilitate motor rehabilitation . -
pubmed
Moreover , we attempted to delineate the role of visual modulation within the virtual environment that affected corticospinal excitability in healthy
subjects and
stroke patients . -
pubmed
METHODS : A total of 18 healthy
subjects and 18
hemiplegic patients were enrolled into the study . -
pubmed
In healthy subjects and
stroke patients , the virtual mirror task with intermittent visual feedback significantly facilitated corticospinal excitability of MEPs compared with continuous visual feedback . -
pubmed
This provides neurophysiological evidence supporting the application of the virtual mirror paradigm using various visual modulation technologies to upper extremity rehabilitation in
stroke patients . -
pubmed
UNLABELLED : The goal of this initial investigation was to examine the potential benefit of a frequency modulation ( FM ) system for 11
children diagnosed with
autism spectrum disorders (
ASD ) ,
attention - deficit hyperactivity disorder (
ADHD ) , or both disorders through measures of speech recognition performance in noise , observed classroom behavior , and teacher - rated educational risk and listening behaviors . -
pubmed
The sequence similarities of this
strain to the members of the family Microbacteriaceae were less than 97 % , with the highest values observed with
Cryobacterium mesophilum MSL-15(T ) ( 96.3 % ) ,
Cryobacterium roopkundense RuGl7(T ) ( 96.2 % ) ,
Labedella gwakjiensis KSW2 - 17(T ) ( 96.2 % ) ,
Cryobacterium luteum Hh15(T ) ( 96.2 % ) ,
Cryobacterium psychrophilum DSM 4854(T ) ( 96.2 % ) ,
Klugiella xanthotipulae 44C3(T ) ( 96.0 % ) and
Amnibacterium kyonggiense KSL51201 - 037 ( T ) ( 96.0 % ) . -
pubmed
The type
strain of
Naasia aerilata is 5116S-4(T ) ( = KACC 15517(T ) = NBRC 108725(T ) ) . -
pubmed
B - cell subsets in
patients with
transient hypogammaglobulinemia of infancy , partial
IgA deficiency , and selective
IgM deficiency . -
pubmed
OBJECTIVE : In the present study , we used flow cytometry to analyze peripheral blood B - cell subsets in
patients with
THI and unclassified
hypogammaglobulinemia (
UCH ) , partial
IgA deficiency , and selective
IgM deficiency . -
pubmed
METHODS : The study population comprised 41
patients with
hypogammaglobulinemia (
THI , 18 ; UCH , 23 ) , 16
patients with partial
IgA deficiency , and 16
patients with selective
IgM deficiency who were admitted to Ankara University Department of Pediatric Immunology - Allergy between January 2010 and April 2011 , as well as 29 healthy controls . -
pubmed
Naive B - cell percentages were significantly higher and activated B - cell values lower in the
THI patients than in the
UCH patients and age - matched healthy controls . -
pubmed
Furthermore , we observed that naive B cell values were higher in
patients with
THI . -
pubmed
METHODS : A deformable image registration tool was used to plan and accumulate dose over all phases of the breathing cycle for conventional and robust - inspired IMRT strategies of eight
nonsmall cell lung cancer patients exhibiting peak - to - peak respiratory motion with amplitudes ranging from 1 to 2 cm in the craniocaudal direction . -
pubmed
In the present study , we report the clinical data in the case of a 46 - year - old female
patient , treated due to 5 - day
forehead swelling accompanied by
dizziness . -
pubmed
The current study addresses this gap by investigating neural responses to a mild visual stress challenge with real - time assessment of adrenal hormones in
women with
MDD in remission and controls . -
pubmed
Fifteen
women with recurrent
MDD in remission ( rMDD ) and 15 healthy control women were scanned on a 3 T Siemens MR scanner while viewing neutral and negative ( stress - evoking ) stimuli . -
pubmed
Compared to controls , rMDD
women demonstrated higher
anxiety ratings , increased
cortisol levels , and hyperactivation in the amygdala and hippocampus , p<0.05 , family - wise error ( FWE)-corrected in response to the stress challenge . -
pubmed
INTRODUCTION : Scaling up routine
HIV testing represents a key component of the National HIV /
AIDS Strategy . -
pubmed
Campylobacter jejuni is an important cause of
human foodborne gastroenteritis ; strategies to prevent
infection are hampered by a poor understanding of the complex interactions between host and pathogen . -
pubmed
The clinical data of 7 newly diagnosed
patients with primary
tonsil DLBCL from October 2009 to February 2013 were analyzed retrospectively . -
pubmed
It is concluded that most
patients with primary
tonsil DLBCL are at early stage , have an obvious characteristics of onset ages , clinical manifestations , pathological histology and achieve better remission through combined chemotherapy and radiotherapy . -
pubmed
METHODS : In this prospective sham - controlled trial ,
infants ( 0 - 6 months ) with symptoms suggestive of
gastroesophageal reflux disease were studied using 8 - hour pH - impedance , cardiorespiratory and video monitoring , direct nurse observation , and a validated questionnaire . -
pubmed
METHODS : The expression of miR-224 in the
cancer tissues and their adjacent tissues in 120
gastric cancer patients were detected by real - time quantitative PCR . -
pubmed
The biological effects of miR-224 ASO on
human gastric cancer SGC7901 cells was assessed by
MTT assay , clone formation assay , flow cytometry and in vivo experiment in
nude mice . -
pubmed
RESULTS : Compared with the control group ( 0.50 + - 0.07 ) , miR-224 ASO significantly reduced the miR-224 mRNA expression in the
cancer patients ( 0.09 + - 0.01 , P & lt ; 0.05 ) . -
pubmed
CONCLUSIONS : MiR-224 is overexpressed in
human gastric cancer . -
pubmed
Improvement of verbal fluency in
patients with
diffuse brain injury over time . -
pubmed
BACKGROUND :
Diffuse axonal injury (
DAI ) , a common cause of neurological sequelae in
patients with
traumatic brain injury (
TBI ) , is considered one of the most prevalent forms of primary
neuronal injury in
patients with severe
TBI . -
pubmed
The aim of the present study was to compare verbal fluency ( VF ) performance at 6 and 12 months after the
trauma in a same group of
patients with
DAI . -
pubmed
METHODS : Eighteen
patients with moderate to severe
DAI and 17 healthy
volunteers were enrolled . -
pubmed
Sixty randomly selected
DM1 patients ( 14.5 + - 3.2 years ) and 30 healthy ( 13.5 + - 2.8 years )
volunteers were enrolled in the study . -
pubmed
Our results indicate that three monocyte subsets are distinguishable in the groups of young
diabetic patients and the healthy , similarly to in the blood of
adults . -
pubmed
DM1 patients were characterized by higher values of apoptotic monocytes than the healthy . -
pubmed
They may be useful for controlling excessive monocyte apoptosis in
diabetic patients . -
pubmed
Power Doppler ultrasonographic assessment of the ankle in
patients with inflammatory
rheumatic diseases . -
pubmed
The aim of this paper is to illustrate the US assessment of
ankle lesions in
patients with inflammatory
rheumatic diseases , including
rheumatoid arthritis ,
spondyloarthritis , and
systemic lupus erythematosus , focusing on the utility of PDUS . -
pubmed
OBJECTIVES : To evaluate the usefulness of the information obtained with SPECT , coronary angio - CT and fusion images , in
patients with stable
ischemic disease who need invasive coronary angiography ( IA ) . -
pubmed
MATERIAL AND METHODS : Forty - six
patients ( 65.98 + -8.3 years ) with
coronary disease were prospectively included . -
pubmed
The fusion images generated after undergoing IA were used to evaluate the performance of these techniques in the diagnosis of
multi - vessel coronary disease , the detection of the culprit vessel and the therapeutic management of these
patients . -
pubmed
However , the performance of fusion images in
patients with stable
ischemic disease , who have undergone a SPECT as the first non - invasive study and need IA , does not seem indicated because they would not have changed the therapeutic management derived from SPECT and IA information . -
pubmed
Endovascular treatment of
abdominal aortic aneurysm in a 26 - year - old
man . -
pubmed
We present endovascular treatment of
abdominal aortic aneurysm in a 26 - year - old
man with a 10 - year follow - up . -
pubmed
A young
patient presenting with an
abdominal aortic aneurysm is extremely rare , and data describing this population are limited . -
pubmed
CONCLUSIONS : Enrichment of diet with
onion as functional ingredient could be proposed as a complementary approach to prevent or partially modulate
vascular dysfunction , reducing some of the risk indexes linked to initial development of
atherosclerosis . -
pubmed
Brainstem evoked potential in newly diagnosed
patients of
subclinical hypothyroidism . -
pubmed
AIMS : The aim is to assess the auditory pathway by brainstem auditory evoked potentials ( BAEPs ) in newly diagnosed
patients of
subclinical hypothyroidism and healthy sex- and age - matched controls . -
pubmed
CONCLUSION : The prolongation of wave V in BAEPs of both ears suggests that the central auditory pathway is affected significantly in subclinical
hypothyroid patients . -
pubmed
PARTICIPANTS : A total of 120
TS patients , aged 0 to 48 years . -
pubmed
Kudo in
rats with spared
nerve injury . -
pubmed
rotata ) is a medical
plant that has been traditionally used for centuries for the treatment of
pain , such as
bone and muscle pain ,
joint pain and
dysmenorrhea . -
pubmed
Randomized trials ( RCT ) show no meaningful improvement in
hypertension control with renal artery stenting ( RAS ) compared to medical therapy alone in
patients with largely moderate
hypertension and intermediate grade
stenoses . -
pubmed
Observational studies of
patients with severe
hypertension and high - grade
stenoses on multiple medications report blood pressure improvement after RAS . -
pubmed
We aimed to study lipid profile 1 year after bariatric surgery and compare its changes between the different procedures in
patients matched for initial weight and
weight loss . -
pubmed
Patients were matched for age ( + -5 years ) , sex , pre - surgery
body mass index (
BMI ) ( + -2 Kg / m(2 ) ) and
excess weight loss ( EWL ) ( + -5 % ) . -
pubmed
Autosomal recessive non - syndromic hearing loss (
ARNSHL ) is one of the most common
genetic diseases in
human and is subject to important genetic heterogeneity , rendering molecular diagnosis difficult . -
pubmed
Motor Skills in
Hearing Impaired Children with or without Cochlear Implant -- A Systematic Review . -
pubmed
A certain percentage of the
patients with
chronic subtalar instability is incorrectly labeled with the diagnosis of a
sinus tarsi syndrome . -
pubmed
The anticancer activities of
pristimerin have been illustrated in various
cancer cell lines and
animal models . -
pubmed
MATERIAL AND METHODS : A total of 195
patients with
BRONJ in the mandible were included in this prospective study . -
pubmed
RESULTS : Recurrence of
BRONJ was significantly reduced ( p = 0.023 ) as was extent of
necrosis ( p = 0.001 ) in
patients with mylohyoid flaps . -
pubmed
PURPOSE : To investigate the effectiveness and application of transcatheter arterial embolization ( TAE ) plus systemic
vincristine for treatment of
corticosteroid - resistant
vascular tumors associated with
Kasabach - Merritt phenomenon in
infants . -
pubmed
MATERIALS AND METHODS : TAE was performed in 17
infants ( average age , 4.3 mo + - 2.4 ; range , 1 - 10 mo ) with
corticosteroid - resistant
vascular tumors associated with
Kasabach - Merritt phenomenon , followed by intravenous
vincristine once weekly for systemic chemotherapy . -
pubmed
Age - related presence of selected viral and bacterial pathogens in
paraffin - embedded lung samples of
dogs with
pneumonia . -
pubmed
In archived
formalin - fixed and paraffin
wax - embedded lung samples from 68 cases with the clinical and histologic diagnosis of
pneumonia the histological pattern of
pneumonia was re - evaluated and the samples were further investigated for the following infectious agents :
canine distemper virus (
CDV ) ,
canine adenovirus type 2 ( CAV-2 ) ,
canine respiratory coronavirus (
CRCoV ) ,
Bordetella ( B. ) - pubmed
The correct detection of
CDV had been achieved in ten out of eleven positive cases ( 90.9 % ) upon initial investigation , but the presence of bacterial pathogens , like
B. - pubmed
While
CDV and
CRCoV infections were exclusively found in dogs younger than one year , the vast majority of
infections with
P. - pubmed
We hypothesized that
OA to articles in
human health or environmental journals was greater than access to animal health literature . -
pubmed
The proportion of
OA journals in animal health ( 40 % ) differed significantly from journals categorized as
human ( 28 % ) , environment ( 28 % ) , and more than 1 category ( 29 % ) . -
pubmed
CONCLUSIONS :
OA to
human health literature is more comparable to animal health than hypothesized . -
pubmed
LPS is a
bacterial cell wall component that is capable of inducing osteoclast formation and pathological
bone resorption . -
pubmed
Potential clinical impact of the film array
meningitis encephalitis panel in
children with suspected
central nervous system infections . -
pubmed
The FilmArray
Meningitis Encephalitis Panel , a multiplex PCR for testing of cerebrospinal fluid , was compared to conventional diagnostic methods in
children with suspected
central nervous system infections . -
pubmed
We report a
patient with long history of
sarcoidosis and
Crohns disease with newly developed
lymphadenopathy which was found to be due to
Castleman ' s disease . -
pubmed
STEMI Secondary to
Coronary Vasospasm : Possible Adverse Event of
Methylphenidate in a 21 - Year - Old
Man with
ADHD . -
pubmed
We present the case of a 21 - year - old
man diagnosed with
ADHD who recently started therapy with
Ritalin Adult 20 mg for at least 3 days . -
pubmed
In 2014 , out of 1140
influenza samples received at the National Influenza Centre , 888 samples ( 78 % ) were
A ( H3N2 ) strains , 244 ( 21.3 % ) were type B
strains , and 8 ( 0.7 % ) were
A ( H1N1 ) pdm09 strains . -
pubmed
Hyperuricemia in
Children and
Adolescents with
Autism Spectrum Disorder Treated with
Risperidone : The Risk Factors for Metabolic Adverse Effects . -
pubmed
Risperidone , one of the atypical antipsychotics , might be related to the
hyperuricemia among
autism spectrum disorder (
ASD )
patients . -
pubmed
The aims of this study were to determine the prevalence of
hyperuricemia in
ASD patients treated with
risperidone and to determine associations between serum
uric acid levels and
risperidone dosage , treatment duration , and metabolic parameters . -
pubmed
Methods : 127
children and
adolescents with
ASD treated with
risperidone and 76 age - matched
risperidone - naive
patients with
ASD were recruited . -
pubmed
Results :
Hyperuricemia was present in 44.70 % of
risperidone - naive
patients with
ASD and 57.50 % of
ASD patients treated with
risperidone . -
pubmed
Conclusion :
Hyperuricemia may play a role in metabolic adverse effect in
children and
adolescents with
ASDs receiving the high dose and/or the long - term treatment with
risperidone . -
pubmed
METHODS :
Patients with
PMS formed the
PMS group and age - matched healthy normal controls were included in the control group . -
pubmed
Patients with
PMS were divided into two subgroups according to coexistence of
FMS or not . -
pubmed
The mean physical component summary of SF-36 was low in the PMS
patient with
FMS . -
pubmed
However , an acute systemic gas and
fat embolic syndrome similar to
DCS in
human divers was described in
beaked whales that stranded in temporal and spatial association with military exercises involving high - powered sonar . -
pubmed
Two
Risso ' s dolphin (
Grampus griseus ) out of 493 necropsied cetaceans stranded in the Canary Islands in a 16 - year period ( 2000 - 2015 ) , had a severe acute
decompression sickness supported by pathological findings and gas analysis . -
pubmed
BACKGROUND :
Chronic low - grade inflammation is believed to contribute , at least in a subset of
patients , to the development of
bipolar disorder (
BD ) . -
pubmed
BACKGROUND : The repair of extensive
upper limb skin lesions in pediatric
patients is extremely challenging due to substantial limitations of flap size and donor - site morbidity . -
pubmed
METHOD : Between March 2013 and August 2016 , 11
patients underwent reconstructive treatment for extensive
skin lesions in the upper extremity using a preexpanded intercostal artery perforator flap . -
pubmed
We aim to report cases of
melanoma patients treated with
diphencyprone in a single Brazilian institution and highlight their outcomes . -
pubmed
Since 2012 , we have treated 16
melanoma patients with
cutaneous metastases with topical
diphencyprone . -
pubmed
We believe topical
diphencyprone is a feasible treatment that can be another option for treating
melanoma patients , especially in cases of in - transit or extensive disease . -
pubmed
Utility of serum
Aspergillus - galactomannan antigen to evaluate the risk of severe acute exacerbation in
chronic obstructive pulmonary disease . -
pubmed
OBJECTIVES : To explore whether serum levels of
Aspergillus - galactomannan antigen could be used to evaluate the risk of severe acute exacerbation of
COPD ( AE -
COPD ) . -
pubmed
METHODS : We measured the Aspergillus - galactomannan antigen levels of 191
patients with stable
COPD , and examined its clinical relevance including AE -
COPD . -
pubmed
High
Aspergillus - galactomannan antigen level ( & gt;=0.7 ) was associated with older age and presence of
bronchiectasis and
cysts on computed tomography images . -
pubmed
Compared to
patients with low Aspergillus - galactomannan antigen level ( & lt;0.7 ) ,
patients with high
Aspergillus - galactomannan antigen level had significantly higher incidence of severe AE -
COPD ( P = 0.0039 , Gray 's test ) and respiratory - related mortality ( P = 0.0176 , log - rank test ) . -
pubmed
METHODS : The study included 77
patients ( 63
men and 14
women ; median age , 78 years ) who underwent elective TEVAR for
aortic arch disease between 2009 and 2013 . -
pubmed
RESULTS : Perioperative
ischemic stroke occurred in nine
patients , and no
patient died within 30 days postoperatively . -
pubmed
Univariate analyses demonstrated that the shagginess score was significantly higher in
patients who developed postoperative
cerebral infarction than in those who did not ( P = .04 ) . -
pubmed
The aim of this study was to assess plasma levels of
monoamine neurotransmitters (
catecholamines ,
indolamines , and intermediate metabolites ) in
patients with
FM and healthy controls to investigate possible alterations in the metabolism of these molecules in
FM . -
pubmed
METHOD : We measured plasma
catecholamines (
epinephrine ,
norepinephrine , and
dopamine ) , as well as
indolamines and intermediary metabolites (
serotonin or
5 - hydroxytryptamine [ 5 - HT ] ,
5 - hydroxyindolacetic acid [
5 - HIAA ] ,
5 - hydroxytryptophan [
5 - HTP ] , and
N - acetyl-5 - hydroxytryptamine [
Nac-5 - HT ] ) in 35
women with
FM and 12 age - matched healthy
women . -
pubmed
RESULTS : Higher levels of
norepinephrine and lower levels of
dopamine ,
5 - HT ,
5 - HIAA , and
5 - HTP were found in
women with
FM in comparison with controls . -
pubmed
CONCLUSIONS : These findings show evidence of the dysregulation of the
catecholamine and
indolamine pathway in
patients with
FM , which may contribute to the physiopathology of this
syndrome . -
pubmed
This article studies the epidemiological and economic impacts of a universal testing and treatment policy of
Human Immunodeficiency Virus (
HIV ) in South Africa . -
pubmed
A total of 72 young
people ( 15 to 25 years old ) with
suicidal ideation / self - injuring behaviour and
BPD traits and symptoms will participate in the study . -
pubmed
Among the 1286
patients with
AIS who underwent spinal fusion , the mean LOS was 4.90 days [ 95 % confidence interval ( CI)=4.84 - 4.97 ; SD=1.19 ] . -
pubmed
Plasmodium falciparum malaria prevalence was positively associated with living in the lake - endemic area ( adjusted odds ratio [ aOR ] 3.46 ; 95 % confidence interval [ 95 % CI ] 1.63 , 7.37 ) , paternal occupation as peasant farmer ( aOR 1.87 ; 1.08 , 3.26 ) or manual laborer ( aOR 1.83 ; 1.00 , 3.37 ) , and keeping dogs ( aOR 1.62 ; 0.98 - 2.69 ) or
cows ( aOR 1.52 ; 0.96 - 2.40 ) inside or near the household . -
pubmed
Plasmodium falciparum malaria prevalence was inversely associated with indoor residual insecticide spraying ( IRS ) ( aOR 0.44 ; 0.19 , 1.01 ) , having a household connected to electricity ( aOR 0.47 ; 0.22 , 0.98 ) , and a household with two ( aOR 0.45 ; 0.22 , 0.93 ) or & gt;= three rooms ( aOR 0.41 ; 0.18 , 0.93 ) . -
pubmed
Tissue Concentrations of
Zinc ,
Iron ,
Copper , and
Magnesium During the Phases of Full Thickness
Wound Healing in a
Rodent Model . -
pubmed
This study analyzed the kinetics of
zinc ,
iron ,
copper and
magnesium concentrations in a full thickness open
wound rat model over 14 days . -
pubmed
We made
wounds with a diameter of 6 mm on the back of Lewis
rats and let them heal naturally prior to analysis by histology and inductively coupled plasma mass spectrometry analysis . -
pubmed
For the assessment of
goiter , HVI for
students aged 8 and 10 years and BMIV for students aged 9 years might serve as better indicators . -
pubmed
MATERIAL AND METHODS : Twenty - seven
teenagers with
TS , aged from 12 to 15 years , and their mothers were included in the main group . -
pubmed
In addition , mothers of
children with
TS were characterized by a high level of
alexithymia and a significantly lower integrative level of emotional intelligence compared to the control group . -
pubmed
Thus , the results indicate the presence of severe
emotional disturbances in
children with
TS and in their mothers . -
pubmed
An anesthetic experience during open heart surgery in a
patient with
Budd - Chiari syndrome combined with
superior vena cava syndrome : A case report . -
pubmed
The
patient was managed successfully without conventional intraoperative hemodynamic monitoring such as central venous catheterization , pulmonary artery catheterization , or transesophageal echocardiography due to underlying
SVCS and the risk of
varix bleeding . -
pubmed
METHODS : Retrospective analysis of
patients with
hyperparathyroidism who have undergone
Tc99m - sestamibi dual - time imaging and parathyroid surgery . -
pubmed
RESULTS : A total of 135
hyperparathyroidism patients met the inclusion criteria . -
pubmed
RESULTS : The prevalence of
peri - implantitis over an average follow - up of 2 years was 34 % on the
patient level and 21 % on the implant level . -
pubmed
CONCLUSIONS : Approximately 1/3 of the
patients and 1/5 of all implants experienced
peri - implantitis . -
pubmed
Effect of
Cyclocarya Paliurus on Hypoglycemic Effect in
Type 2 Diabetic Mice . -
pubmed
The
DM mice were divided into 3 groups : a DM group , a DM+CPE ( 0.5 g / Kg ) group , and a DM+
CPE ( 1.0 g / Kg ) group . -
pubmed
Anxiolytic and stimulant drugs facilitated learning at doses which did not impair locomotion , suggesting that pharmacological manipulation of other factors in addition to fear /
anxiety can impact aversive learning in
zebrafish . -
pubmed
Clinical Utility of Targeted Next - Generation Screening of Peripheral Blood in the Evaluation of
Patients with
Cytopenias . -
pubmed
A total of 58 ( 80.55 % )
patients had acute
infarction lesions on the diffusion weighted imaging ( DWI ) . -
pubmed
After 3 months of follow - up , two
patients had recurrent
ischemic stroke . -
pubmed
Regardless of the high frequency of
infarction in CWS
patients , more than 80 %
patients had a favorable functional prognosis . -
pubmed
Cervical internal carotid artery tortuosity : A morphologic analysis of
patients with
acute ischemic stroke . -
pubmed
BACKGROUND AND PURPOSE :
Cervical internal carotid artery ( ICA ) tortuosity is thought to impede distal catheterization during attempted mechanical thrombectomy in
patients with
acute ischemic stroke . -
pubmed
METHODS : A retrospective review was completed of neck CTAs of
patients with
acute ischemic stroke due to a large
vessel occlusion that underwent attempted endovascular recanalization . -
pubmed
Effect of Changing Diet on
Gastric Ulceration in Exercising
Horses and Ponies After Cessation of
Omeprazole Treatment . -
pubmed
Diet is an accepted risk factor for
equine squamous gastric disease (
ESGD ) , but there is little published evidence for the benefit of dietary change ( DC ) . -
pubmed
Our data showed that
ALA but not LA supplementation alleviated
systolic blood pressure elevation and improved
ACh - induced , endothelium - dependent vasodilation in both spontaneously
hypertensive rats ( SHRs ) and AngII - induced
hypertensive mice . -
pubmed
Liver biopsy remains the gold standard in evaluating
NASH ; however , noninvasive methods are accumulating evidence for a growing role in identifying
patients at increased risk to develop
NASH ,
fibrosis , and potentially
cirrhosis . -
pubmed
Interestingly , new research in
animal models of
HGPS has demonstrated impressive lifespan improvements secondary to metabolic interventions . -
pubmed
CONCLUSION : This is the first systematic assessment of TAVR for elderly
patients with
aortic stenosis . -
pubmed
Accommodation and stereopsis in
adults with
traumatic brain injury . -
pubmed
The aim of this study is to evaluate accommodation , stereopsis deficits and
visual symptoms in Chinese
patients with
traumatic brain injury . -
pubmed
METHODS : This is a cross - sectional study that included 22
patients with
traumatic brain injury and 22 controls ; the refractive status , stereoacuity , and accommodative ability of each subject were measured . -
pubmed
RESULTS :
Patients with
traumatic brain injury were significantly more symptomatic than controls ( p < 0.001 ) . -
pubmed
Near stereoacuity thresholds were significantly elevated in
patients with
traumatic brain injury compared to controls ( p < 0.001 ) . -
pubmed
Patients with
traumatic brain injury showed greater accommodative lag to 2.5 D ( p = 0.03 ) , 3 D ( p = 0.03 ) , 4 D ( p = 0.004 ) and 5 D ( p = 0.001 ) stimuli , but not to the 2 D ( p = 0.10 ) stimulus . -
pubmed
CONCLUSION :
Patients with
traumatic brain injury have
deficits in accommodation and stereopsis . -
pubmed
A 59 - year - old
man , with a background of multiply
relapsed myeloma , presented with a 3 - week history of
confusion , short - term
memory impairment and behavioural changes . -
pubmed
We present this case as an example of
PML in a patient with
multiple myeloma , highlighting the need to consider this diagnosis in an enlarging population of heavily treated , severely immunocompromised ,
patients . -
pubmed
The aim of the study was to evaluate the alteration in the expression of these biomarkers in a group of
autism spectrum disorder (
ASD )
children . -
pubmed
Peripheral blood mononuclear cells ( PBMCs ) were obtained from 37
autistic patients . -
pubmed
changes regardless of the direction ) of miR-181b were significant in
autistic children . -
pubmed
Furthermore ,
tumor xenograft models in
nude mice were established to test
tumor growth and weight . -
pubmed
MATERIALS AND METHODS : Between 2000 and 2014 , a total of 284 T4 -
NSCLC patients who underwent lung resection ( mediastinal organ invasion , n = 114 ; ipsilateral different lobe
tumors , n = 32 ; and
tumors larger than 7 cm , n = 138 ) were included in the present study . -
pubmed
The 5 - year survival rates were 46 % for ipsilateral different lobe
tumors , 45.4 % for
tumours larger than 7 cm , and 36.6 % for mediastinal organ invasion ( 28 % for
patients with heart / atrium invasion , 43.3 % for carina invasion , 37.5 % for large vessel invasion ) ( p = 0.223 ) . -
pubmed
CONCLUSION : According to the results of our study , surgical treatment is a good option in T4 -
NSCLC patients who have no mediastinal lymph node
metastasis and are completely resectable . -
pubmed
Helicobacter pylori monoclonal
strains were isolated from patients with eradication failure . -
pubmed
Tofacitinib is approved for the treatment of moderate to severe active
rheumatoid arthritis (
RA ) in adult
patients who do not respond adequately or are intolerant to one or more disease - modifying anti - rheumatic drugs . -
pubmed
Embolectomy was performed in the remaining four
patients for the treatment of acute
ischemia of the extremities . -
pubmed
This retrospective study was designed to evaluate the risk factors and outcomes of
patients with severe
stenosis of the
SA who underwent PTAS complicated by
aortic dissection . -
pubmed
All
patients had
hypertension and a high severity of
SA stenosis ( 85.0 + - 13.0 % , 60 - 95 % ) . -
pubmed
All
patients had spontaneous resolution of the
aortic dissection with conservative treatment . -
pubmed
A 29 - year - old
man with a
marfanoid habitus , peculiar
mucosal neuromas of the lips and tongue ,
high arched palate ,
hyperplastic corneal nerves , and
hypertension was found at operation to have
medullary carcinoma of the thyroid ,
parathyroid hyperplasia , and
pheochromocytoma . -
pubmed
The eradication of
bovine brucellosis in New Zealand : History and objectives . -
pubmed
A double - blind controlled study of
seratonin uptake inhibitor (
Zimelidine ) versus placebo in
chronic pain patients . -
pubmed
Forty
patients with
pain syndromes of both organic and
psychogenic origin of at least 6 months ' duration were included in a double - blind controlled study of a new rather selective
serotonin uptake inhibitor ,
Zimelidine , versus placebo . -
pubmed
Patients in the
Zimelidine group experienced significantly more
pain relief and tended to be able to reduce their need for analgesics more often than the
patients in the placebo group . -
pubmed
In the
Zimelidine group 4
patients were excluded due to
nausea and intestinal troubles versus only 1
patient in the placebo group . -
pubmed
[ Sex ratio of inbred
strains of
mice ] . -
pubmed
A study of the sex ratio in
mice of the inbred
strains ( CBA and C3H ) and connection of the postimplantation embryonic mortality in
mice of these
strains with the sex distribution of embryos demonstrated that the sex ratio in these
mice was 1:1 . -
pubmed
Literature and the author 's personal data suggested that genetic features of
mice of the inbred
strains failed to influence significantly the sex ratio of the offspring . -
pubmed
The postimplantation embryonic
death rate in the C3H
mice exceeded that in the CBA
mice ( 14.4 and 9.3 % , respectively ) . -
pubmed
However , the balanced sex ratio in
mice of these
strains points to the absence of selective mortality of the embryos of any one sex during embryogenesis . -
pubmed
In order to localize bronchodilators site of activity we studied the maximal expiratory flow - volume curves breathing air and 80 percent-20 percent
helium -
oxygen mixture in 11 normal and 23
asthmatic children . -
pubmed
Oral antibiotic therapy for
skeletal infections of
children . -
pubmed
Peak synovial fluid concentrations were greater than 60 % of peak serum concentrations with all drugs tested and there was adequate inhibitory activity against
bacteria commonly causing
arthritis . -
pubmed
Estimation of ferrokinetic parameters by a mathematical model in
patients with primary acquired
sideroblastic anaemia . -
pubmed
Ferrokinetic parameters were estimated in eight
patients with primary acquired
sideroblastic anaemia (
PASA ) by means of a mathematical model of
iron kinetics . -
pubmed
By using silicone rubber injections we have studied the blood supply to the cervical skin in
human cadavers before and after the elevation of flaps . -
pubmed
The
lambs were treated with
albendazole ( SmithKline Beecham ) ,
fenbendazole ( Hoechst Roussel ) or a vitamin supplement and their
weight gains were followed over the next 7 months . -
pubmed
This paper reports a series of 10
patients re - irradiated with external - beam techniques for local
recurrence of
soft - tissue sarcoma of the limb and limb girdle following initial limb conserving management with surgery and radiotherapy ( dose range 33 - 60 Gy ) . -
pubmed
Five
patients re - treated with radical intent ( dose range 40 - 60 Gy ) had a median survival of 36 months and median
recurrence - free survival of 16 months . -
pubmed
All five
patients treated palliatively ( dose range 12 - 50 Gy ) have died , although two demonstrated local control until
death . -
pubmed
Radionecrosis was seen in one
patient who was re - irradiated twice ( total dose 145 Gy ) and subsequently required amputation . -
pubmed
Two hundred
patients were randomly selected for either a partial or a total meniscectomy for a
meniscal tear during open operation . -
pubmed
Patients with bucket - handle ,
anterior and posterior horn tears had similar functional results after total meniscectomy . -
pubmed
Maternal - iron - deficiency effects on peritoneal macrophage and peritoneal natural - killer - cell cytotoxicity in
rat pups . -
pubmed
Cytotoxicity of peritoneal macrophages ( pMs ) and peritoneal natural killer ( pNK ) cells toward xenogenic
tumor cells was studied in anemic , suckling
rats . -
pubmed
A case is reported to reinforce that
Entamoeba histolytica should be considered in the differential diagnosis of all patients presenting with
liver abscess , whether they have travelled abroad or not . -
pubmed
Instrumented near - term pregnant
ewes received 1 - h maternal infusion of
ethanol ( 1 g / kg maternal
body weight ) followed 0.5 h later by a 3 - h fetal infusion of
indomethacin ( 1 mg / kg
fetal body weight / h ) , and then a 2 - h fetal infusion of
PGE2 ( 400 ng / kg
fetal body weight / min ) . -
pubmed
Xanthine - containing
urinary calculi in
dogs given
allopurinol . -
pubmed
Clinical features and laboratory findings were evaluated in 10
dogs that formed
xanthine - containing
urinary calculi during the period that they were given
allopurinol ( 9 to 38 mg / kg of
body weight / d ) . -
pubmed
Of the 10
dogs , 9 ( all
Dalmatians ) had formed
uric acid - containing
calculi at least once before
allopurinol treatment was initiated . -
pubmed
Sodium ,
ATP , and intracellular pH transients during reversible complete
ischemia of
dog cerebrum . -
pubmed
We examined the temporal relationships among transcellular
sodium , energy metabolism , and intracellular pH with
sodium and
phosphorus magnetic resonance spectroscopy in a new , hemodynamically stable , brain stem - sparing model of reversible , complete
cerebral ischemia in eight anesthetized
dogs . -
pubmed
This study was undertaken to reveal whether variations in
oxygen supply in the postischemic period following
forebrain ischemia in
rats affect
free radical production and the
brain damage incurred . -
pubmed
To that end ,
rats ventilated on
N2O /
O2 ( 70:30 ) were subjected to 15 min of transient
ischemia . -
pubmed
In a parallel series ,
animals ventilated with one of the three gas mixtures in the early recirculation period , respectively , were allowed to recover for 7 days , with subsequent perfusion - fixation of brain tissues and light microscopical evaluation of the
brain damage . -
pubmed
Hyperoxic animals failed to show increased tissue
H2O2 production , while
hypoxic ones showed a tendency towards decreased production . -
pubmed
Several complications of antihypertensive therapy particularly threaten elderly
hypertensive drugs
patients . -
pubmed
Hypotensive responses to
tryptophan and
5 - hydroxytryptophan infusions were studied in normotensive male
Sprague - Dawley rats . -
pubmed
Pharmacokinetics of
famotidine in elderly
patients with and without
renal insufficiency and in healthy young
volunteers . -
pubmed
Elimination half - life in the elderly
patients with
renal insufficiency was significantly prolonged compared to the elderly
patients with normal renal function and the young
volunteers . -
pubmed
In a prospective study to determine the accuracy of intravenous DSA in the diagnosis of
ulcerative lesions of the internal carotid artery , preoperative findings obtained from DSA in
patients with suspected
cerebrovascular disease were reviewed and compared with thrombendarterectomy specimen ( n = 74 ) . -
pubmed
Four
patients with
oligoamenorrhea manifesting hormonal and clinical features of
polycystic ovarian disease (
PCOD ) were selected for treatment . -
pubmed
It may be assumed that either subcutaneous administration is inadequate in
PCOD patients or that the frequency of
pulses needed to correct the hormonal disturbances in
PCOD patients differs from that needed for ovum maturation and ovulation . -
pubmed
The findings on routine pre - operative palpation of the axilla in
patients with infiltrative
breast carcinoma are compared to the results of histological quantitation of the nodal lymphoid tissue and its
tumour deposits in 91 consecutive cases in which a standardized axillary dissection had been carried out . -
pubmed
The efficiency of spontaneous ventilation during
halothane anaesthesia was investigated in 18
infants and
children with
congenital heart disease presenting either with hyperperfusion and left - to - right shunt ( group LR : n = 10 ,
body weight 3.7 - 16 kg ) or with hypoperfusion and right - to - left shunt ( group RL : n = 8 ,
body weight 3.4 - 12 kg ) . -
pubmed
The mean Pr2 concentrations in eight
patients with
disseminated intravascular coagulation and six asymptomatic
individuals with
congenital antithrombin deficiency not receiving antithrombotic therapy were not significantly elevated as compared with those of normal controls ( 0.244 nmmol / L and 0.242 nmol / L vs. 0.184 nmol / L , respectively ) . -
pubmed
Given that the t1/2 of F1 + 2 is estimated to be approximately 90 minutes , the low plasma levels of Pr2 observed in
patients with
thrombophilia can not result from rapid clearance of this component. -
pubmed
In contrast , the hepatocytes of
animals that drank the 3 %
glucose solution did not display the rarefied hyaloplasm or
disorientation of cellular organelles and resembled the hepatocytes of control
animals . -
pubmed
[ Intracranial blood volume during gravitational stress in
rats adapted to
hypoxia ] . -
pubmed
Thirty - four
patients admitted for a suspicion of
septicaemia were treated with
ceftriaxone , a third generation
cephalosporin . -
pubmed
The only observed secondary effect was a
drug fever occurring in 3
patients who remained
febrile in spite of a general improvement . -
pubmed
[ Clinical significance of stress - induced ST segment changes in
patients with previous
myocardial infarction : evaluation by
201Tl myocardial single photon emission computed tomography ] . -
pubmed
The disrupting action of neuroleptic
haloperidol on the
amphetamine - induced stereotype is weakened in
animals with ventral lesions and enhanced in those with
dorsal lesions . -
pubmed
The data obtained and the clinical trials carried out by the authors suggest introduction of the physiological doses of
thiamine ,
calcium pantothenate and
ascorbic acid into the diet of the
workers in order to prevent
phenol poisonings more effectively . -
pubmed
Treatment of fears and
phobias in
dogs . -
pubmed
Left ventricular performance in endotoxin
shock in
dogs . -
pubmed
Because of reports of late deterioration , we studied six
dogs until spontaneous
death ( 9 - -18 h ) . -
pubmed
Six
couples with
immunologic infertility were treated with
corticosteroids . -
pubmed
are Gram - negative non - fermentative bacteria which may be isolated as commensals from
human skin , throat and intestine but are also increasingly responsible for
hospital infections . -
pubmed
Owing to frequent changes in their taxonomy , their pathogenic role in
humans has not been clear but
today acinetobacter is considered to be a significant nosocomial pathogen in outbreaks of
hospital infections predominantly in intensive care units . -
pubmed
A 55 - kilodalton antigen encoded by a gene on a
Borrelia burgdorferi 49 - kilobase plasmid is recognized by antibodies in sera from patients with
Lyme disease . -
pubmed
burgdorferi DNA expression library ( N40
strain ) with
rabbit anti -
B. - pubmed
Of 11 enterotoxigenic
strains , 7 were
A. - pubmed
Genes specifying identical activities were detected in various
strains of
L. - pubmed
We report a prospective study of 46
patients with acute complete
dislocation of the acromioclavicular joint . -
pubmed
Follow - up was from 2 to 7.9 years ( mean 5.8 ) , and at the latest review only five
patients ( 10.9 % ) had redisplacement , due to premature removal of wires for
infection in one , to migration of the wires in another and to partial failure of the muscle repair in three . -
pubmed
There has been an explosion in our understanding of how nerve cells in
mammals respond to
O2 deprivation and what are the mechanisms involved in nerve cell
injury or survival . -
pubmed
Further , we have characterized the distribution of these receptors / channels complexes in the CNS of the
rat and in an
anoxia - resistant
animal : the turtle . -
pubmed
Surgical resection of
adenomas cures in most
patients with the disorder . -
pubmed
Droloxifene inhibits cortical bone turnover associated with
estrogen deficiency in
rats . -
pubmed
Droloxifene (
DRO ) , an
estrogen antagonist / agonist , has been shown to possess
estrogen - like effects in inhibiting bone turnover leading to
cancellous bone loss in ovariectomized ( OVX )
rats . -
pubmed
Endogenous opioid tone in
patients with
rheumatoid arthritis . -
pubmed
Seven
RA patients with active and established disease and eight healthy
controls were studied . -
pubmed
Stuffed
animals as a bedside clinical clue may suggest evaluation for
Borderline Personality Disorder . -
pubmed
Sham - operated controls and unoperated
rats that had been pre - exposed to a light stimulus prior to light -
shock pairings showed less conditioned suppression towards the light stimulus than the nonpre - exposed
animals , thus demonstrating LI . -
pubmed
In this retrospective study , oncologic and functional results of 24
patients treated for
glomus jugulare tumor stages C and D are reported . -
pubmed
Surgically induced
cranial nerve palsies developed in 38 % of the
patients . -
pubmed
Seven
patients had incomplete
tumor removal requiring postoperative irradiation , with
tumor progression occurring in 2
patients . -
pubmed
Reactivity of the basilar artery was measured in untreated nondiabetic and
diabetic rats and in nondiabetic and
diabetic rats treated with a daily intraperitoneal injection of
dimethylthiourea (
DMTU ; 50 mg / kg ) . -
pubmed
Dilatation of the basilar artery in response to
nitroglycerin was similar in untreated and
DMTU - treated nondiabetic and
diabetic rats . -
pubmed
The
C6 glioma in the immune - competent
rat is a frequently used model in
brain tumor gene therapy research . -
pubmed
It displays the histologic hallmarks of the
human glioblastoma and has been employed to demonstrate new mechanisms of anti -
tumor immunity and therapeutic strategies . -
pubmed
We noted that
C6 tumors regressed spontaneously in three of five
animals and that protective anti -
tumor immunity ensued without therapeutic intervention . -
pubmed
A review of the literature revealed that different
rat strains are used as " syngeneic " host for the
C6 cell glioma , namely , BDIX , BDX , Sprague - Dawley , and Wistar . -
pubmed
These data suggest that the
C6 glioma model in the immune - competent
rat should no longer be used to study gene therapy strategies , that the available data obtained in this model need to be critically reinterpreted , and that findings obtained in the
C6 glioma model may not be sufficient to support a clinical trial in
glioblastoma patients . -
pubmed
The technique of lymphoscintography was initially used to identify the sentinel node / s in
patients with
malignant melanoma . -
pubmed
A proposed alternative management strategy to routine axillary lymph node dissection in
patients with
breast cancer is sentinel lymph node localization using lymphoscintography and biopsy of the identified sentinel node . -
pubmed
Loss of tolerance to
amphetamine - induced
hypophagia in
rats : homeostatic readjustment vs. instrumental learning . -
pubmed
To avoid the expression of
dyskinesias in already primed
patients , agents that act on either the
dopamine or nondopaminergic receptors have been used . -
pubmed
Letrozole for the treatment of pretreated advanced
breast cancer patients : preliminary report . -
pubmed
Twenty
patients ( pts ) with metastatic
breast cancer with
disease progression , previously treated with chemotherapy and
tamoxifen , were administered oral
letrozole ( 2.5 mg / day ) therapy . -
pubmed
These results suggest that the in vitro sperm - egg interaction assay accurately reflects the fertilizing ability of fresh and stored
duck spermatozoa and detects
spermatozoal damage due to semen storage more sensitively than motility or fertility tests . -
pubmed
RESULTS : Of 414
patients with suspected upper
gastrointestinal bleeding , 379 were endoscoped . -
pubmed
CONCLUSIONS : Blood in the stomach reflects clinical features in
patients with acute
upper gastrointestinal bleeding and is reduced by treatment with
lansoprazole and
tranexamic acid . -
pubmed
Bifidobacteria populations in fermented milks should be over 10(6 ) bifidobacteria / g at the time of consumption of
strain added to the product . -
pubmed
OBJECTIVES : Hypopituitary
adults with
growth hormone deficiency (
GHD ) have an increased cardiovascular mortality , although the mechanisms remain unclear . -
pubmed
The influence of two concentrations of
sodium hypochlorite on
human blood : changes in
haemolysis , pH and protein . -
pubmed
Blood concentrations of
cyclosporin a during long - term treatment with
cyclosporin a ophthalmic emulsions in
patients with moderate to severe
dry eye disease . -
pubmed
To quantify blood
cyclosporin A (
CsA ) concentrations during treatment with
CsA topical ophthalmic emulsions , blood was collected from 128
patients enrolled in a Phase 3 , multicenter , double - masked , randomized , parallel - group study of
CsA eyedrops for treatment of moderate to severe
dry eye disease . -
pubmed
The near - isogenic line ( NIL ) TA1150 contains a 56 - cM introgression from
Lycopersicon chmielewskii chromosome 1 and has several interesting phenotypic characteristics including fruit with orange color , high levels of soluble solids , thick pericarp , small stem
scars , and good firmness . -
pubmed
It is concluded that there is a higher risk of developing
cervical dysplasia in HIV - seropositive women who carry the
human papillomavirus . -
pubmed
Phase I trial of
tirapazamine and
cyclophosphamide in
children with refractory
solid tumors : a pediatric oncology group study . -
pubmed
One
child with
neuroblastoma had prolonged stable disease ( 10 cycles ) at a dose of 250 mg / m(2 ) . -
pubmed
This
patient had disease detectable in the bone marrow only and all evidence of
bone marrow involvement resolved for 17 cycles of therapy . -
pubmed
However , these guidelines can be questioned with regard to the extent of efficacy as well as the rationale for not using strong opioids as first - line treatment , especially in terminal
cancer patients . -
pubmed
The purpose of this randomized study was to prospectively compare the efficacy and tolerability of strong opioids as first - line agents with the recommendations of the WHO in terminal
cancer patients . -
pubmed
One hundred
patients with mild - moderate
pain were randomized to treatment according to WHO guidelines or to treatment with strong opioids . -
pubmed
Evaluated outcomes included
pain intensity , need for change in therapy , quality of life , Karnofsky Performance Status , general condition of the
patient , and adverse events . -
pubmed
No between - treatment differences were observed for changes in quality of life or performance status , but
patients started on strong opioids had significantly better
pain relief than
patients treated according to WHO guidelines ( P=0.041 ) . -
pubmed
Additionally ,
patients started on strong opioids required significantly fewer changes in therapy , had greater reduction in
pain when a change was initiated , and reported greater satisfaction with treatment than the comparator group ( P=0.041 ) . -
pubmed
These data suggest the utility of strong opioids for first - line treatment of
pain in
patients with
terminal cancer . -
pubmed
This analysis indicates that once - daily dosing ( 7 mg / kg ) of
gentamicin should achieve satisfactory concentration in
patients with normal renal function although serum concentration monitoring is required to confirm the optimal dosing interval in
patients with
impaired renal function . -
pubmed
DESIGN AND METHODS : Fifty - five
patients with
ET were evaluated . -
pubmed
Pain - related fear and daily functioning in
patients with
osteoarthritis . -
pubmed
In the current study , the authors investigated this hypothesis in
patients with
bladder carcinoma . -
pubmed
OBJECTIVE : The objective was to investigate associations between dietary macronutrients and progression of
coronary atherosclerosis among postmenopausal
women . -
pubmed
DESIGN : Quantitative coronary angiography was performed at baseline and after a mean follow - up of 3.1 y in 2243 coronary segments in 235 postmenopausal
women with established
coronary heart disease . -
pubmed
METHODS : This study reviewed 298
scoliosis patients ( 107
male , 191
female ) who underwent anterior and/or posterior operation . -
pubmed
On the other hand , the presence of the
strain did not interfere with the growth of certain species of normal intestinal microbiota , such as
Enterococcus fecalis ,
Escherichia coli ,
Bifidobacterium bifidum or
Bacteroides fragilis . -
pubmed
We reviewed 61 hips in 50
children ( 33
boys and 17
girls ) with
slipped capital femoral epiphysis (
SCFE ) , all treated by in situ pinning . -
pubmed
The authors critically reviewed the medical literature on SSRIs to identify subgroups of
patients at risk of
bleeding complications . -
pubmed
In this study , we modelled the drugs used in practice on
human prostate cancer cell lines . -
pubmed
With the use of various cytostatics , the cell proliferation - inhibiting effects were measured under in vitro conditions on
human prostate cancer cell lines
LNCaP - FGC and
PC-3 . -
pubmed
METHODS :
Pulpal necrosis was induced in
foxhounds along with surgical removal of radicular buccal bone . -
pubmed
OBJECTIVE : The aim of the study was to determine whether the forced oscillation technique ( FOT ) , which does not require active cooperation , may be useful to assess bronchial responsiveness in
patients with suspected occupational
asthma (
OA ) . -
pubmed
METHODS : Changes in resistances evaluated by FOT , and DeltaFEV1 measured during
methacholine challenge test were compared in 77
adults referred for suspected
OA . -
pubmed
The study group included 20 adult
patients ( 9
men , 11
women , mean age 57.2 years ) with
ASD who had undergone successful closure with the Amplatzer occluder . -
pubmed
Two
patients complained of
amaurosis fugax at 1 and 3 months after the procedure , and two
patients complained of
blurred vision at 3 and 4 months after the procedure . -
pubmed
In conclusion , microembolic events do not appear to be the cause of the ocular complaints in
patients with
ASD treated with Amplatzer occluder . -
pubmed
We present an unusual case of a
patient with an acute retrobulbar
optic neuropathy , secondary to a ruptured
anterior communicating artery aneurysm . -
pubmed
METHODS : A 29 - year - old
woman was assessed for an acute , isolated unilateral
optic neuropathy of unknown origin . -
pubmed
Although an initial encephalic MRI was believed to be normal , an underlying ruptured
anterior communicating artery aneurysm was eventually diagnosed when the
patient became
stuporous because of
intracranial bleeding . -
pubmed
DESIGN AND METHODS : We investigated 136 newly diagnosed
APL patients from four Italian Institutions . -
pubmed
INTERPRETATION AND CONCLUSIONS : Our findings suggest that immunophenotypic analysis can distinguish a subset of
APL patients with different biological characteristics . -
pubmed
Salmonella was lodged mainly in the mid- and hindgut 3 days after the infective meal , minimizing transmission through
vomit . -
pubmed
Topical gene transfer to the airways of
cystic fibrosis (
CF )
patients has been inefficient , partly due to extracellular barriers such as sputum . -
pubmed
CASE REPORT : We report on a 76 - year - old
patient who presented with an atypical
hydrocele testis . -
pubmed
Administered with
sorbitol , it usually has minor adverse effects , but it may cause colonic or intestinal
necrosis in
uremic patients . -
pubmed
We report an unusual case of rectal
stenosis due to
SPS crystals in a 46 - year - old
man . -
pubmed
The
patient had been involved in a car accident with severe
thoracic and abdominal trauma . -
pubmed
The combination of plasmapheresis with these cytotoxic agents and
steroids is effective in
patients with
Goodpasture ' s syndrome , especially if instituted early in the course of the disease . -
pubmed
Recent evidence suggests that
patients with severe
ANCA - associated vasculitis , defined by the presence of diffuse
alveolar haemorrhage and/or severe
renal involvement (
creatinine concentration & gt ; 5.7 mg / dl ) , might benefit from plasma exchange in combination with
cyclophosphamide and
corticosteroids . -
pubmed
The
HIV epidemic in China has been increasing exponentially , yet there have been no studies of the neurobehavioral effects of
HIV infection in that country . -
pubmed
Ultrasound - doppler coupled with
gadolinium - enhanced MR or CT angiography has proven adequate for most
patients with
RAS . -
pubmed
Stenting completed angioplasty is worthwhile in most
patients with
atherosclerotic RAS . -
pubmed
ACE inhibitors decrease mortality and increase renal function in
patients with
RAS . -
pubmed
Higher
infection of
dengue virus serotype 2 in
human monocytes of patients with
G6PD deficiency . -
pubmed
Human monocytes from peripheral mononuclear cells collected from 12
G6PD - deficient patients and 24 age - matched controls were infected with one of two
DENV serotype 2 (
DENV-2 ) strains - the New Guinea C
strain ( from a case of
dengue fever ) or the 16681
strain ( from a case of
dengue hemorrhagic fever ) with a multiplicity of
infection of 0.1 . -
pubmed
Experimental results indicated that the monocytes of
G6PD - deficient patients exhibited a greater levels of
infection with
DENV-2 New Guinea C
strain than did those in healthy controls [ mean+/-SD:33.6%+/-3.5 ( 27.2 % approximately 39.2 % ) vs 20.3%+/-6.2 ( 8.0 % approximately 30.4 % ) , P<0.01 ] . -
pubmed
Similar observations were made of
infection with the
DENV-2 16681 strain [ 40.9%+/-3.9 ( 35.1 % approximately 48.9 % ) vs 27.4%+/-7.1 ( 12.3 % approximately 37.1 % ) , P<0.01 ] . -
pubmed
To our knowledge , this study demonstrates for the first time higher
infection of
human monocytes in
G6PD patients with the
dengue virus , which may be important in increasing epidemiological transmission and perhaps with the potential to develop more severe cases pathogenically . -
pubmed
Thresholds of risk factors for
ischemic stroke in
type 2 diabetic patients with and without
albuminuria : a non - linear approach . -
pubmed
PATIENTS AND METHODS : This is a prospective cohort study with 6969 Chinese
type 2 diabetic patients without history of
stroke after a median follow - up of 5.36 years . -
pubmed
We sought to identify pharmacodynamic factors involved in partial
desmopressin response or
desmopressin resistance in
children with monosymptomatic
nocturnal enuresis , with special emphasis on concentrating performance , and time to reach and duration of maximal urine concentration . -
pubmed
MATERIALS AND METHODS : We evaluated 64
children with monosymptomatic
nocturnal enuresis and proved nocturnal
polyuria lacking full response to
desmopressin treatment . -
pubmed
After an oral fluid load given at the start of the test the majority of
patients failed to reach maximal concentration of urine as voided during
hydropenia , and 45
patients failed to regain appropriate dilution of urine even when an oral water load of 15 ml / kg ( urine osmolality less than 750 mOsmol / l ) was given in the morning at the end of the test . -
pubmed
Cardiovascular and autonomic phenotype of db / db
diabetic mice . -
pubmed
The db / db
mice serve as a good model for
type 2 diabetes characterized by
hyperinsulinaemia and progressive
hyperglycaemia . -
pubmed
OBJECTIVE : To determine the frequency and possible cognitive effect of histological
Alzheimer ' s disease (
AD ) in autopsied older nondemented
individuals . -
pubmed
STUDY DESIGN : All
trauma patients admitted from January 2005 to April 2007 in a Level I
trauma center were divided into a nondelayed ( & lt;or=6 hours ) group or a delayed ( & gt;6 hours ) group . -
pubmed
Hospitals with a large
trauma / emergency general surgery caseload resulting in delays in ED throughput should institute policies and procedures for triage of more severely injured patients for early ICU admission and develop a monitoring system to ensure that delays do not adversely affect
patient outcomes . -
pubmed
We investigated the antioxidant effect of different extracts of non - transformed ( S ) and transformed
pineapple ( with the magainin gene construct , [ TS ] , for
disease resistance ) . -
pubmed
Use of quantum dots to detect
human papillomavirus in
oral squamous cell carcinoma . -
pubmed
OBJECTIVE : To examine the association of
oral squamous cell carcinoma with
human papillomavirus (
HPV ) using quantum dots ( QD ) in situ hybridization ( ISH ) . -
pubmed
METHODS : Expression of
HPV16/18 was analyzed in a representative collection of 21
oral squamous cell carcinomas by tissue microarrays . -
pubmed
RESULTS : Seven cases out of 21 ( 33.3 % ) were
positive for QDISH while 1 out of 21 ( 4.8 % ) was positive for ISH , although all of
HPV DNA were localized in the nuclei in the spinous and basal cell layer of the epithelium . -
pubmed
OBJECTIVES : The aim of this study was to investigate the determinants of serum total
homocysteine level ( tHcy ) in
patients with
type 2 diabetes mellitus (
DM ) according to sex . -
pubmed
Fifteen
patients with
PD performed index finger , hand tapping and horizontal pointing movements as well as reach - to - grasp movements with either hand before ( baseline conditions ) and after a period of 1 Hz rTMS preconditioned by ( 1 ) sham , ( 2 ) anodal or ( 3 ) cathodal tDCS over the primary motor cortex contralateral to the more affected body side . -
pubmed
We used pseudoislets self - organized from a population of the
insulinoma cell line
MIN6 , derived from a transgenic
mouse expressing the large T - antigen of
SV40 in pancreatic beta - cells , as an experimental model for the study of cell nanoencapsulation . -
pubmed
Although specific mediators of hepatic lipotoxicity have not been identified with certainty , abundant evidence from
animal studies and recent data in
humans indicate that
free fatty acids in the liver can serve as substrates for formation of
nontriglyceride lipotoxic metabolites that cause
liver injury . -
pubmed
In this study , we examined the roles of
phosphatidylinositol 4,5 - bisphosphate [
PI ( 4,5 ) P ( 2 ) ] and
PI ( 4,5 ) P ( 2 )-producing enzymes in invadopodia formation in
MDA - MB-231 human breast cancer cells . -
pubmed
The cumulative incidence of severe
AKI within 100 days in
patients with an HCT - CI score 0 , 1 - 2 , and & gt;=3 was 21.3 % , 48.8 % , and 73.9 % , respectively . -
pubmed
The purpose of this study was to investigate the clinical factors predictive of
bacteremia in low - risk
febrile neutropenia at initial
patient evaluation . -
pubmed
Patients who met the criteria of low - risk
febrile neutropenia at the time of visit to emergency department after anti -
cancer chemotherapy were included in the analysis . -
pubmed
Patients with low score points had low rate of
bacteremia , thus , would be candidates for outpatient - based or oral antibiotic therapy . -
pubmed
We present a clinical case of a 63 years old
patient with
abdominal pain and
weight loss . -
pubmed
We observed a significant decrease in DA concentrations in the ME and
hyperprolactinemia in an exposure - dependent manner similar to that seen in OCE
rats . -
pubmed
Refractive error and visual functions in
children with special needs compared with the first grade school students in oman . -
pubmed
A pediatrician reviewed the health records of all the
children at the time of their enrollment in this study to determine if the child had been diagnosed with a systemic condition or
syndromes . -
pubmed
We estimated the rates and the risk of different
visual function defects in
children with special needs . -
pubmed
RESULT : The prevalence of
refractive error in 70
children ( 4.7 + - 0.8 years ) with special needs ( group 1 ) and 175 normal healthy first grade
students ( group 2 ) were 58.5 % and 2.9 % , respectively . -
pubmed
Six
children in this group had
defective near vision . -
pubmed
Sixteen ( 80 % )
children with
Down syndrome had
refractive error . -
pubmed
Seven ( 50 % )
children with
developmental disorder showed decreased contrast sensitivity . -
pubmed
CONCLUSION : Prevalence of uncorrected
refractive error was much higher in
children with special needs . -
pubmed
Prevalence of
strabismus ,
nystagmus , and reduced contrast sensitivity was also higher in
children with special needs . -
pubmed
We present a
child with
neuroblastoma , successfully treated without radiation therapy , who developed
mid - aortic syndrome and
hypertension . -
pubmed
The incidence of
mid - aortic syndrome in
children with
neuroblastoma is unknown . -
pubmed
RESULTS : For
glioblastoma patients in the ALA study , median survival was 16.7 and 11.8 months for complete versus partial resection , respectively ( P & lt ; 0.0001 ) . -
pubmed
For
glioblastoma patients who received & gt;=90 % resection in the
BCNU wafer study , median survival increased for
BCNU wafer versus placebo ( 14.5 versus 12.4 months , respectively ; P = 0.02 ) , but no survival increase was found for & lt;90 % resection ( 11.7 versus 10.6 months , respectively ; P = 0.98 ) . -
pubmed
METHODS : Eight
RA patients with a disease duration & lt ; or = 1 year received 40 mg
adalimumab subcutaneously every 2 weeks . -
pubmed
It also ameliorated
carotid atherosclerosis and arterial stiffness in
patients with early
RA . -
pubmed
PATIENTS : 325
patients with
CAD requiring cardiovascular surgery with an ASA of III or above . -
pubmed
HHV-8 - associated multicentric
Castleman ' s disease in HIV - negative patient : a novel therapy for an
orphan disease . -
pubmed
Photodynamic therapy using a novel photosensitizer ,
TONS501 , is similarly effective to
ALA and EC036 photodynamic therapy on
DMBA - and
TPA - induced
mouse skin papilloma . -
pubmed
OBJECTIVE : Using
7 , 12 - dimethylbenz [ a ] anthracene (
DMBA ) and
12 - omicron - tetradecanoylphorbol-13 - acetate (
TPA)-induced
mouse skin papilloma model , we compared the efficacy of
ALA- ,
TONS501- , and TONS504 - PDT on the
skin tumor regression . -
pubmed
METHODS : Following application of
ALA ,
TONS501 , TONS504 ointment or TONS501 lotion on
DMBA- and
TPA - induced
mouse papillomas , 670 nm laser irradiation by LD670 - 05 diode laser was performed . -
pubmed
CONCLUSION : A novel TONS501ointment - PDT shows potent anti -
tumor effect on
DMBA- and
TPA - induced
mouse skin papilloma and might be more useful for the clinical applications . -
pubmed
Newcastle disease (
ND ) is a highly contagious , severe disease of poultry caused by pathogenic
strains of
Newcastle disease virus (
NDV ; or avian paramyxovirus-1 ) . -
pubmed
Most of the published
strains are outbreak - associated strains , while the apathogenic
NDV strains that occur in wild birds , posing a constant threat to poultry with their capability to convert into more virulent forms , have remained less studied . -
pubmed
Animal models of antipsychotic - related
weight gain and
animal transgenic models of knockout or overexpressed genes of antipsychotic receptors have been largely evaluated by scientific community for changes in
obesity - related gene expression or phenotypes . -
pubmed
In this paper , we summarize current thinking on : ( 1 ) the role of polymorphisms in several candidate genes , ( 2 ) the possible roles of various neurotransmitters and neuropeptides in this
adverse drug reaction , and ( 3 ) the state of development of
animal models in this matter . -
pubmed
The
patient was managed in a single session with a combination of classic open surgical and endovascular techniques in order to treat his
aneurysms and revascularize his leg . -
pubmed
Evolutionary history of
human disease genes reveals phenotypic connections and comorbidity among
genetic diseases . -
pubmed
In this work , we report that phenotypically similar
diseases are connected by the evolutionary constraints on
human disease genes . -
pubmed
Human disease groups can be classified into slowly or rapidly evolving classes , where the
diseases in the slowly evolving class are enriched with morphological phenotypes and those in the rapidly evolving class are enriched with physiological phenotypes . -
pubmed
Furthermore , the high comorbidity found between
diseases connected by similar evolutionary constraints enables us to improve the predictability of the relative risk of
human diseases . -
pubmed
We find the evolutionary constraints on
disease genes are a new layer of molecular connection in the network - based exploration of
human diseases . -
pubmed
Which
patients are at a high risk of
ASC and need emergency drainage is still unclear . -
pubmed
METHODS : We analyzed 359 consecutive
patients with
acute cholangitis who had been admitted to the First Affiliated Hospital , Zhejiang University School of Medicine from January 2004 to May 2011 . -
pubmed
Of the remaining 358
patients with an average age of 62.7 years ( range 17 - 90 ) , 162 were diagnosed with
ASC , and 196 with non - ASC . -
pubmed
Complications were identified in 11
patients ( 3.1 % ): mild
pancreatitis occurred in 8
patients and
hemorrhage in 3
patients . -
pubmed
In this work ,
Artemia franciscana was used as test organism model , studying mortality against several
strains of
M. - pubmed
Adrenal insufficiency in a peritoneal dialysis
patient taking
megestrol acetate . -
pubmed
Case 35 - 2012 : A
man with
weakness ,
anorexia , and diffuse
pain . -
pubmed
[ Application of
levosimendan in acute
heart failure patients with symptoms of
low cardiac output : case series report ] . -
pubmed
The report presents single centre experience in application of
levosimendan in
patients with acute
heart failure with
low cardiac output . -
pubmed
METHODS :
Patients undergoing
aneurysmal repair at two neurovascular referral centres between September 2005 and August 2010 were included ;
patients who underwent coiling for
recurrences of prior microneurosurgical clipping were excluded . -
pubmed
We present the case of a 28 - year - old
woman with postoperative pathologically - proven LCAS with right liver
metastases . -
pubmed
The
butanol fermentation using solventogenic clostridial
strains , particularly
Clostridium acetobutylicum , is a very old industrial process (
acetone -
butanol -
ethanol - ABE fermentation ) . -
pubmed
In this review , some newly engineered solvent - producing Clostridium
strains are described and
strains of which sequences are available are compared with
C. - pubmed
Dynamic contrast - enhanced and diffusion - weighted magnetic resonance imaging noninvasive evaluation of vascular disrupting treatment on
rabbit liver tumors . -
pubmed
The purpose of the study is to evaluate consecutive changes of 20
rabbit VX2
liver tumors after VDT by dynamic contrast - enhanced MRI ( DCE - MRI ) and diffusion - weighted imaging ( DWI ) at a 3.0 T MR unit . -
pubmed
We report a postmenopausal
woman , who experienced two episodes of
TCM within 4 months following emotional and physical stress . -
pubmed
PATIENTS AND METHODS : This cross - sectional study was carried out on
ESRD patients treated with HD in Imam Khomeini Hospital , Ahvaz city , Southwest of Iran . -
pubmed
RESULTS : Out of 47
ESRD patients , 27 were male ( 57.4 % ) and 20 were female ( 42.6 % ) , with mean age of 55.27 + - 8.1 years . -
pubmed
The mean time of
HD in
HEV positive and negative patients were 1224.2 and 1168.5 days , respectively with no significant association ( P = 0.88 ) . -
pubmed
Herein , we report on three
patients with
gastric cancer in remnant stomach who underwent laparoscopic total gastrectomy with intracorporeal esophagojejunostomy successfully . -
pubmed
Our experience has suggested that laparoscopic total gastrectomy with intracorporeal esophagojejunostomy can be a safe , feasible and promising option for
patients with
gastric cancer in remnant stomach . -
pubmed
In this work , biosurfactant production by a
Pseudomonas aeruginosa strain was optimized using low - cost substrates . -
pubmed
Among the known
human HEV strains ( genotypes 1 , 2 , 3 and 4 ) , the genotype 2 Mexican isolate has two ' double - base ' substitutions ( 5'U5100G5101 CU/3'C5117U5118 GG ) flanking the conserved cis - reactive element ( CRE ) in the intergenic - junction sequences . -
pubmed
Multiple sequence alignment of intergenic - junction of
human HEV strains showed further base conservations flanking the CRE sequences . -
pubmed
Here , we provide laboratory evidence that net ( gross calcification minus dissolution ) and gross calcification rates of three
common cold - water corals ,
Caryophyllia smithii ,
Dendrophyllia cornigera , and
Desmophyllum dianthus , are not affected by pCO2 levels expected for 2100 ( pCO2 1058 muatm , Omegaara 1.29 ) , and nor are the rates of skeletal dissolution in
D. - pubmed
Reply :
Coxiella burnetii and complicated
atherosclerosis : perhaps neither innocent nor bystanders . -
pubmed
Although significant advances have been made in treatment for
ccRCC , a significant percent of
patients have no benefit from currently available treatment option . -
pubmed
A total of 43 % of bronchoscopic examinations were nondiagnostic for
lung cancer , and invasive procedures were performed after bronchoscopy in 35 % of
patients with benign lesions . -
pubmed
[ Relationship between blood pressure , heart rate and
cardiac autonomic dysfunction in non - diabetic obese
patients ] . -
pubmed
Cardiac autonomic dysfunction (
CAD ) affects a high proportion of
obese patients . -
pubmed
Our aim was to examine the relationship between
CAD , HR and BP in obese
patients without known
diabetes . -
pubmed
PATIENTS AND METHODS : We included 428
overweight or obese
patients . -
pubmed
CONCLUSION : These data indicate that among
overweight or obese
patients with a defect in cardiac vagal activity BP is elevated only in those with a high heart rate , which is indicative of a more marked
insulin resistance and probably an excess in sympathetic activity . -
pubmed
The etiological agent that was most frequently isolated from materials gathered from patients diagnosed with
SSI ,
BSI and
SST was
Staphylococcus aureus . -
pubmed
A 46 - year - old
man with acute
low - back pain . -
pubmed
The effects of aquatic trunk exercise on gait and muscle activity in
stroke patients : a randomized controlled pilot study . -
pubmed
[ Purpose ] The purpose of this study was to investigate the relationship between muscle activity and gait function following aquatic trunk exercise in
hemiplegic stroke patients . -
pubmed
[ Subjects and Methods ] This study 's participants included thirteen
hemiplegic patients ( ten males and three females ) . -
pubmed
DESIGN AND METHODS : Peripheral blood mononuclear cells from young
TS patients ( n = 24 , 17.4 - 35.9 years ) and healthy controls ( n = 16 ) were stained with various Treg markers to characterize their phenotypes . -
pubmed
Based on the presence of
thyroid autoimmunity ,
patients were categorized into
TS ( - ) ( n = 7 ) and
TS ( + ) ( n = 17 ) . -
pubmed
The FM
patients were assessed using the following self - reported questionnaires : the Medical Outcomes Study Short - Form Health Survey , the
Fibromyalgia Impact Questionnaire , the Brief Fatigue Inventory , the Beck Depression Inventory , the State - Trait Anxiety Inventory , the Self - Efficacy Scale , and the Social Support Scale . -
pubmed
Malaria caused by
Plasmodium vivax has recently shown resistance to
chloroquine in some places . -
pubmed
METHODS :
Patients aged 13 - 65 years with confirmed mono -
infection of
P. - pubmed
METHODS AND RESULTS : The study comprised two equally sized cohorts of
patients that had undergone retrospectively gated cardiac CT :
patients who had MACE and/or all - cause
death at follow - up and a matched ( age , sex , and risk factors ) event - free cohort . -
pubmed
Of 166
patients , 31.3 % experienced
MACE and 28.9 % died of any cause ( follow - up 22.9 + - 13.4 months ) . -
pubmed
Strabismus in
patients with cortical
visual impairment : outcomes of surgery and observations of spontaneous resolution . -
pubmed
PURPOSE : To investigate the rate of spontaneous resolution of
strabismus in
patients with cortical
visual impairment (
CVI ) at a single center over a 10 - year period and to evaluate the success rate of
strabismus surgery . -
pubmed
METHODS : The medical records of
patients with
CVI and
strabismus seen between October 2003 and October 2013 were reviewed retrospectively . -
pubmed
Patients were classified into 4 outcome groups : ( 1 ) those who experienced spontaneous resolution of
strabismus , ( 2 ) those with persistent
strabismus who did not undergo surgery , ( 3 ) those who achieved postoperative alignment of & lt;=10(Delta ) ; and ( 4 ) those whose final postoperative alignment was 11(Delta)-25(Delta ) or & gt;25(Delta ) . -
pubmed
Of these , 11
patients ( 16 % ) experienced spontaneous resolution of
strabismus , 27 ( 38 % ) were observed without receiving surgery , and 32 ( 46 % ) underwent
strabismus surgery . -
pubmed
The
patients who did not undergo surgery were significantly older at presentation ( 36 months vs 12 - 15 months ; P = 0.03 ) ; otherwise , there were no significant differences between groups in age at surgery or spontaneous resolution , type of
strabismus , or underlying cause of
CVI . -
pubmed
CONCLUSIONS : In our study cohort , a minority of
patients with
CVI and
strabismus ( 16 % ) experienced spontaneous resolution of
strabismus . -
pubmed
Strabismus surgery can be reasonably successful in properly selected
patients with
CVI and
strabismus . -
pubmed
These
patients show considerable rates of resolution of their
strabismus , either spontaneously or through surgery . -
pubmed
The effect of
aliskiren on the
renal dysfunction following unilateral
ureteral obstruction in the
rat . -
pubmed
Sarcopenia is closely associated with
pancreatic exocrine insufficiency in
patients with
pancreatic disease . -
pubmed
METHODS : Data were collected prospectively on 132
patients with
pancreatic disease . -
pubmed
CONCLUSIONS :
Sarcopenia is independently associated with PEI in
patients with
pancreatic disease . -
pubmed
Preparation of a cell line persistently infected with
maedi /
visna virus and production of viral antigens . -
pubmed
Dermatophytosis is one of the most common
human infections affecting both immunocompetent individuals and immunocompromised patients , in whom the disease is more aggressive and can reach deep tissues . -
pubmed
MATERIALS AND METHODS :
Human SH - SY5Y neuroblastoma cells were exposed to a 50 Hz , 100 muT MF with or without non - phototoxic level of blue light for 24 h. We also studied whether these treatments alter responses to
menadione , an agent that induces mitochondrial
superoxide (
O2 - ) production and DNA damage . -
pubmed
The 1 - year
dog toxicity study is no longer required by certain pesticide regulatory jurisdictions , including the United States and the European Union . -
pubmed
:
Human infection by orthopoxviruses is being reported with increasing frequency , attributed in part to the cessation of
smallpox vaccination and concomitant waning of population - level immunity . -
pubmed
Pseudomonas pachastrellae strain CCUG 46540 T (
KMM 330 T ) was isolated from a deep - sea sponge specimen collected in the Philippine Sea at a depth of 750 m. The draft genome has an estimated size of 4.0 Mb , exhibits a G+C content of 61.2 mol% , and is predicted to encode 3,592 proteins , including pathways for the degradation of aromatic compounds . -
pubmed
Ciprofloxacin could be considered in the treatment of
zoonotic Salmonellosis in
humans . -
pubmed
Therapeutic Mechanisms of
Vernonia amygdalina Delile in the Treatment of
Prostate Cancer . -
pubmed
However , to the best of our knowledge , no previous reports have explored its therapeutic efficacy against
human prostate cancer . -
pubmed
The objective of the present study was to assess the anticancer activities of VAD methanolic extracts in the prevention and treatment of
prostate cancer using
human androgen - independent
prostate cancer (
PC-3 ) cells as a test model . -
pubmed
In Vivo Tracking of
Human Adipose - derived Mesenchymal Stem Cells in a
Rat Knee
Osteoarthritis Model with Fluorescent Lipophilic Membrane Dye . -
pubmed
In order to support the clinical application of
human adipose - derived mesenchymal stem cell ( haMSC ) therapy for
knee osteoarthritis (
KOA ) , we examined the efficacy of cell persistence and biodistribution of haMSCs in
animal models . -
pubmed
Subsequently , intra - articular injection of the labeled cells in
rats with surgically induced
KOA was monitored dynamically by an in vivo imaging system . -
pubmed
This approach has been shown to be an efficient tracking method for haMSCs in a
rat KOA model . -
pubmed
MATERIALS AND METHODS : Members of the Endourologic Disease Group for Excellence research consortium prospectively enrolled
patients with a
renal stone burden ranging from 5 to 20 mm in this study . -
pubmed
In addition to their anti -
fatigue and anti -
anoxia roles in traditional medicine ,
Rhodiola total extract and
salidroside have also displayed medicinal properties as anti -
cardiovascular diseases and anti -
cancer agents . -
pubmed
Objective : To investigate the correlation between Ishak
inflammation score and the clinicopathological characteristics and
recurrence of
patients with
hepatocellular carcinoma (
HCC ) after curative resection , and then set up a
recurrence nomogram for
HCC . -
pubmed
Methods : A total of 326 patients with
HCC after curative resection from January 2006 to December 2009 were studied retrospectively as training cohort and 110
HCC patients after surgery from January 2010 to December 2012 were used as validation cohort . -
pubmed
Results : According to Ishak
inflammation score ,
patients were divided into four subgroups : Grade I(1 - 4 scores ) , Grade II(5 - 8 scores ) , Grade III ( 9 - 12 scores ) and Grade IV(13 - 18 scores ) . -
pubmed
Multivariate analysis showed that Ishak
inflammation score(P=0.007 ) ,
HBV - DNA load(P<0.01 ) ,
tumor size(P=0.001 ) and microvascular invasion(P=0.001 ) were related with the
recurrence of
HCC patients . -
pubmed
A total of 69
wounds in 64
patients were treated with an average
wound size of 36.32cm2 . -
pubmed
This study assessed the bronchodilator efficacy and safety of different doses of this formulation in
patients with
COPD to identify the optimal dose for further development . -
pubmed
In this research , the complete genome sequence of
strain SM30 T was determined , and its methylotrophy modules were characterized . -
pubmed
CONCLUSION : Central line bundle programs were found to be effective in decreasing central line - associated
bloodstream infection rates , improving
patients ' quality of life by preventing ports removal due in pediatric
cancer patients . -
pubmed
This study aims to ( a ) estimate gender differences of the
hepatotoxicity and toxicokinetics in
rats after oral administration of
emodin ( 60 and 150 mg / kg / d ) for a consecutive 28 days and ( b ) clarify relative mechanisms caused by glucuronidation and disposition . -
pubmed
Hepatotoxicity was significantly higher in female
rats than that in
male rats , as evidenced by histopathological and biochemical tests . -
pubmed
The new pathophysiological insights might be of relevance for the development of therapeutic strategies for
caveolinopathy patients targeting improved protein folding capacity . -
pubmed
Twelve
patients with
RS with different etiologies were selected and photogrammetric images were obtained prospectively in 3
patients with
RS in whom mandibular growth in the first year of life was determined . -
pubmed
METHOD :
Acute liver failure was induced in
mice using
thioacetamide (
TAA ) ( 200 mg / kg , i.p ) once a day for two consecutive days . -
pubmed
The sensor is reversible and the real - time sensing response is within 30 s. The results benefit the
NO breath detection for
patients with
chronic inflammatory airway disease , such as
asthma . -
pubmed
A Randomized Open - Label Clinical Study Comparing the Efficacy , Safety , and Bioavailability of
Calcium Lysinate with
Calcium Carbonate and
Calcium Citrate Malate in
Osteopenia Patients . -
pubmed
Methodology : A total of 24
osteopenia patients were randomly divided into three groups of eight
subjects in each . -
pubmed
Epizootic hemorrhagic disease (
EHD ) is a
viral arthropod - borne disease affecting wild and domestic ruminants , caused by
infection with epizootic hemorrhagic disease virus (
EHDV ) . -
pubmed
Percutaneous biopsy was performed in 14
patients and
FNH was diagnosed in nine
patients , and
hepatic adenoma ,
hepatocellular carcinoma ,
plasmacytoma ,
angiosarcoma , and atypical
hepatocellular proliferation in one
patient each . -
pubmed
Brain radionecrosis was registered in 6 % of
patients . -
pubmed
MATERIALS AND METHODS : Retrospective analysis was conducted of 433
patients who underwent endovascular
aneurysm repair ( EVAR ) of
aortoiliac aneurysms with the use of Zenith stent grafts from 2007 to 2016 . -
pubmed
Only 1 of 5
patients who underwent repeat intervention had a preoperative diagnosis of
type IIIb endoleak , reflecting the difficulty in its diagnosis . -
pubmed
Type IIIb
endoleaks should always be considered in
patients with sac expansion after EVAR . -
pubmed
A 42 - year - old
man presented paroxysmal sharp
pain in the right side of the head . -
pubmed
Therefore , this model is useful in evaluating mechanisms of cellular activation , peripheral tolerance and homeostatic immune imbalance involved in
human SLE . -
pubmed
A prospective , multicenter study of low - dose
decitabine in adult
patients with refractory
immune thrombocytopenia . -
pubmed
We conducted a prospective , multicenter study to evaluate the efficacy and safety of low - dose
decitabine in adult
patients with refractory
immune thrombocytopenia . -
pubmed
Adult
patients who did not respond to , did not tolerate , or were unwilling to undergo splenectomy , with either a baseline platelet count less than 30 x 109 per L or the presence of
bleeding symptoms and further need of ITP - specific treatments , were enrolled . -
pubmed
In conclusion , low - dose
decitabine is potentially effective and safe in the management of
adults with refractory
immune thrombocytopenia . -
pubmed
The
( + -)- 2,3 - dihydro-4 ' , 8,8 '- trihydroxy -( 1,1 '- binaphthalen )- 4 ( 1H )- one showed selective inhibitory activity on
tumor cells growth , preliminarily supporting the application of
Juglans regia flowers to protect against
cancers in a few Chinese folk areas . -
pubmed
Non - steroidal anti - inflammatory drug ( NSAID ) therapy in
patients with
hypertension , cardiovascular , renal or gastrointestinal comorbidities : joint APAGE / APLAR / APSDE / APSH / APSN / PoA recommendations . -
pubmed
RESULTS : Whenever possible , a NSAID should be avoided in
patients with treatment - resistant
hypertension , high risk of
cardiovascular disease and severe
chronic kidney disease (
CKD ) . -
pubmed
The aim of this study is to investigate the timing of intubation of
children with fulminant
EV71 infection . -
pubmed
We used
rhombencephalitis grading to describe the neurological presentation of these
patients . -
pubmed
Mechanisms affecting exercise ventilatory inefficiency - airflow obstruction relationship in male
patients with
chronic obstructive pulmonary disease . -
pubmed
METHODS : A total of 120 male
patients with
chronic obstructive pulmonary disease were enrolled . -
pubmed
Effect of a Concurrent Cognitive Task , with Stabilizing Visual Information and Withdrawal , on Body Sway Adaptation of
Parkinsonian 's
Patients in an Off - Medication State : A Controlled Study . -
pubmed
The aim of this study was to evaluate the role of the visual deprivation and a cognitive task on the static balance in earlier stage
PD subjects . -
pubmed
Methods : Fifteen off - medication state pwPD ( 9
women and 6
men ) , 67.7 + - 7.3 years old , diagnosed
PD since 5.4 + - 3.4 years , only Hoehn and Yahr state 2 and fifteen young control
adults ( 7
women and 8
men ) aged 24.9 + - 4.9 years , performed semi - tandem task under four randomized experimental conditions : eyes opened single - task , eyes closed single - task , eyes opened dual - task and eyes closed dual - task . -
pubmed
Chronic airway allergy induces pro - inflammatory responses in the brain of wildtype
mice but not 3xTgAD
mice . -
pubmed
Bronchoalveolar lavage fluid analysis confirmed
eosinophilia in both genotypes , but the basal levels of eosinophils were lower in 3xTgAD
mice . -
pubmed
In summary ,
allergy induced predominantly anti - inflammatory effects in 3xTgAD
mice , and pro - inflammatory effects in WT
mice , thus being another potential factor to be considered when studying
AD pathogenesis . -
pubmed
AIMS :
Intervertebral disc degeneration (
IVDD ) has been regarded as the main cause of
low back pain , which affects 80 % of
adults and still lack effective treatment . -
pubmed
Total 166
Escherichia coli ,
Klebsiella pneumoniae and
Klebsiella oxytoca were isolated from urine ,
wound swab ,
pus , sputum and blood samples of patients of Dhaka Medical College Hospital . -
pubmed
Few
animal models with
neoplasia have been studied concerning the circulating
tumor cells and it is likely that CTCs may have a predictive , diagnostic or therapeutic value . -
pubmed
Herein , the authors review all studies in which
human CTCs were transplanted into animals . -
pubmed
Prevalence and Severity of
Diabetic Retinopathy in
Patients with
Macular Telangiectasia type 2 . -
pubmed
PURPOSE : To study the prevalence and severity of
diabetic retinopathy (
DR ) in
patients with
macular telangiectasia type 2 (
MacTel2 ) . -
pubmed
Diabetes mellitus type 2 was present in 50
patients ( 49 % ) and
hypertension in 47
patients ( 46 % ) . -
pubmed
Both eyes ( 1 % ) in one
patient progressed to moderate
DR . -
pubmed
CONCLUSION : Although
diabetes mellitus was highly prevalent among
MacTel2 patients , there were no
patients with severe or proliferative
DR , or
DME in our study . -
pubmed
4 - -10 years after the
injury 31
patients appeared at the check - inspection . -
pubmed
Stereotypic and
hypothermic effects of
apomorphine and
N - n - propylnorapomorphine in
mice . -
pubmed
Two dopaminergic agonists ,
apomorphine (
APO ) and
N - n - propylnorapomorphine (
NPA ) were compared in
mice for their ability to induce stereotypic cage - climbing and
hypothermia . -
pubmed
During the past eight years , we have treated three
patients with
olfactory neuroblastoma by a combination of extensive local surgery using the lateral rhinotomy approach with ethmoidectomy and medial partial maxillectomy , combined with either preoperative or postoperative irradiation therapy . -
pubmed
Dermatophilosis (
streptothricosis ) in a
buffalo calf (
Bubalus bubalis ) . -
pubmed
Myocardial biopsies from two
patients who had developed " stone heart " (
myocardial rigor mortis ;
ischemic contracture of the left ventricle ) were studied by electron microscopy . -
pubmed
Prolonged
cardiac arrest and complete
AV block during upright tilt test in young
patients with
syncope of unknown origin -- prognostic and therapeutic implications . -
pubmed
The purpose of this study was to define the history and prognosis of 12
patients ( 8
males , 4
females ) with
syncope of unknown origin ( 5 to 15 episodes ) , who developed prolonged
asystole or complete
AV block during the upright tilt test ( UTT ) . -
pubmed
These
patients were selected from a larger group of 92 cases with positive UTT out of a total of 136
subjects who were referred for
recurrence of
syncope . -
pubmed
During follow - up ( mean , 17 + /- 5.4 months ) , four
patients had
recurrences but none experienced episodes of life - threatening
syncope . -
pubmed
These
patients do not show an enhanced risk of
sudden death , and drug therapy seems to improve their clinical course . -
pubmed
Between 1987 and 1991 we performed a unilateral or bilateral frontoorbital advancement to correct trigono- or
plagiocephaly in 10
children : Three - dimensional CT provides an exact basis for operation planning . -
pubmed
From 1967 to 1991 we have diagnosed and treated 73
adrenal tumors in 63
patients : 12
pheochromocytomas , 24
adrenal cortical adenomas , 15
hyperplasias , 16
carcinomas , 3
myelolipomas , 2
cysts and 1
neuroblastoma . -
pubmed
Five
patients , 1 with localized secondary
amyloidosis , are described . -
pubmed
A sonicate antigen and two concentrations of a purified flagellum antigen of
Borrelia burgdorferi were compared for serological diagnosis of
Lyme borreliosis by an enzyme immunoassay ( EIA ) . -
pubmed
It is concluded that purified
Borrelia burgdorferi flagellum antigen is superior to a sonicate antigen , especially for serodiagnosis of the early stages of
Lyme borreliosis . -
pubmed
To evaluate the progression of
idiopathic mitral valve prolapse (
MVP ) , a long time follow - up study ( mean 7.1 years ) was performed using echocardiography in 27 cases ( 11
males , 16 females , mean age : 50.4 years ) . -
pubmed
Isolation of
human T - lymphotropic virus type III from the tears of a patient with the
acquired immunodeficiency syndrome . -
pubmed
Human T - lymphotropic virus type III ( HTLV - III ) was isolated from the tears of 1 out of 7 patients with the
acquired immunodeficiency syndrome (
AIDS ) or the
AIDS - related complex . -
pubmed
Thirteen
patients were entered into an uncontrolled pilot study to investigate the response to , and
toxicity of , a combination of
cisplatinum ( 20 mg / m2 ) and
bleomycin ( 6 mg / m2 ) infused daily for 5 days and repeated every 21 days up to a maximum of 4 cycles , in the treatment of
squamous cell carcinoma of the bronchus . -
pubmed
All
patients have been followed to
death . -
pubmed
Lupus vulgaris caused by
Mycobacterium bovis . -
pubmed
The
patients fell into the following diagnostic categories : postnecrotic
cirrhosis 28 , primary
biliary cirrhosis 20 ,
sclerosing cholangitis 19 ,
miscellaneous diseases 14 ,
carcinoma /
neoplasia 12 and
fulminant hepatitis 7 . -
pubmed
Metabolic adjustments to dynamic hypoxic
hypoxemia in
feline brain tissue . -
pubmed
The opportunity to study well - preserved biopsy tissue from a 38 - year - old
man with the acute onset of
dementia and
AIDS encephalopathy prompted this report . -
pubmed
Seventeen
patients aged 47 - 67 years had 20 foci of disappearing
breast calcifications . -
pubmed
Efficacy of
5 - vinyl-1 - beta - D - arabinofuranosyluracil (
VaraU ) against
herpes simplex virus type 2
strains in cell cultures and against experimental
herpes encephalitis in
mice : comparison with
acyclovir and
foscarnet . -
pubmed
The sensitivity of different
herpes simplex virus type 2 (
HSV-2 ) strains to inhibition by
5 - vinyl-1 - beta - D - arabinofuranosyluracil (
VaraU ) was evaluated in comparison to
9 -( 2 - hydroxyethoxymethyl ) guanine (
ACV ;
acyclovir ) and
trisodiumphosphonoformate (
Na3PFA ;
foscarnet ) , using a plaque inhibition assay in primary
rabbit testes ( PRT ) cells as well as in
human embryonic lung fibroblast ( HELF ) cell cultures . -
pubmed
Their in vivo efficacy was assessed in a
mouse encephalitis model . -
pubmed
Complications of combined radical hysterectomy - postoperative radiation therapy in
women with early stage
cervical cancer . -
pubmed
[ Periodontal condition of 15
children with
acute lymphatic leukemia or
Hodgkin ' s lymphoma before and after induction therapy ] . -
pubmed
In
patients with combined
aortoiliac and femoropopliteal occlusive disease , severe involvement of the deep femoral artery ( DFA ) has often been considered an indication for simultaneous aortofemoral and femorodistal bypass grafting . -
pubmed
Effect of high
calcium diet on
magnesium ,
catecholamines , and blood pressure of
stroke - prone spontaneously
hypertensive rats . -
pubmed
To test the effect of a high dietary
calcium intake on blood pressure , we fed
stroke - prone spontaneously
hypertensive ( SHR - SP ) and Wistar - Kyoto
rats ( WKY ) diets containing ( a ) 0.25 %
Ca/0.08 %
Mg , ( b ) 4.0 %
Ca/0.02 %
Mg , and ( c ) 4.0 %
Ca/0.08 % mg , beginning at 6 weeks of age . -
pubmed
SHR - SP and WKY
rats receiving 4 %
Ca with the lower
Mg content had
lower blood pressures ,
hypomagnesemia , and
hypomagnesuria , and grew poorly . -
pubmed
SHR - SP receiving 4 %
Ca and the higher
Mg diet had blood pressures no different from those of
rats receiving the 0.25 %
Ca diet , in spite of having lower
body weights . -
pubmed
[
Asthma associated with the handling of
green coffee beans ] . -
pubmed
Rat hepatocyte - mediated
bacterial mutagenicity in relation to the carcinogenic potency of
benz ( a ) anthracene ,
benzo ( a ) pyrene , and twenty - five methylated derivatives . -
pubmed
[ Use of physical training in the rehabilitation of
patients with
post - infarct heart failure ] . -
pubmed
The effect of exercise was examined in 15
postmyocardial - infarction patients showing clinical signs of
heart failure ; 17
patients were taken as controls . -
pubmed
In addition to a considerable increase in physical working capacity , the
patients doing exercise showed more favorable hemodynamic response to stress that featured a greater
stroke index , a smaller heart rate increment and a more significant fall in specific peripheral resistance . -
pubmed
Ultracytochemical studies of lysosomal function in the macrophages of
human leprosy -- I. -
pubmed
A comparison between subjective audiometric and objective electrophysiological thresholds in
patients with
tinnitus . -
pubmed
The second control group was composed of 8
patients suffering from
sensorineural hearing loss without
tinnitus . -
pubmed
A
patient with
ulcerative colitis and
primary sclerosis cholangitis confirmed by liver biopsy and endoscopic retrograde cholangiography presented with severely altered liver function tests . -
pubmed
A 25 - year - old
woman with long - standing
hypergammaglobulinemic purpura developed distal
renal tubular acidosis and a urine - concentrating defect . -
pubmed
Specific antigen exclusion and non - specific facilitation of antigen entry across the gut in
rats allergic to food proteins . -
pubmed
Among the
cervical cancer patients , the incidence of elevated
TPA levels increased with stage of disease from 12 % in the preinvasive stage to 67 % in the advanced stage . -
pubmed
Similarly , the
TPA values were elevated in 35 % of the
endometrial cancer patients . -
pubmed
Among the
patients with
ovarian malignancies , serum
TPA was elevated in the following order :
LGM cases ( 33 % ) , Stage I ( 44 % ) , and advanced ( 88 % ) . -
pubmed
However , serum
TPA was elevated in 22 % of the
patients with
uterine myoma and in 12 % of those with
ovarian benign tumors . -
pubmed
The current observations demonstrate that the lack of
tumor specificity of
TPA limits its diagnostic value in
gynecologic malignancies , but that serial measurements of this antigen appear to be useful for the evaluation of therapy and monitoring of
patients . -
pubmed
[ Leukocytotoxic antibodies in
patients with different types of
leukemias ] . -
pubmed
[ Study using a new ultrafiltration technic of Bence Jones protein in
patients with
paraproteinemia ] . -
pubmed
Letter :
Hamsters as sentinels for
leishmaniasis and arboviruses . -
pubmed
Effect of
rubella vaccine on
transplacental rubella virus infection in
rabbits . -
pubmed
Survival of
children with severe
chronic uremia . -
pubmed
Antigenic variation in a
strain of
Trypanosoma congolense transmitted by
Glossina morsitans . -
pubmed
[ A contribution to the clinical picture of the mesenteric form of
human Pasteurella pseudotuberculosis infection ] . -
pubmed
Light - induced susceptibility of
Phaseolus vulgaris L. to
tobacco mosaic virus infection . -
pubmed
[ Study of the receptor sensitivity to
glucagon in
patients with
bronchial asthma ] . -
pubmed
Hypercalcaemia occurring after ten weeks of immobilisation was observed in four adult
patients all of whom had had prior
renal failure sufficient to require renal dialysis . -
pubmed
Abuse of
alcohol and
tobacco ,
mineral deficiencies ,
malnutrition , the use of
sorghum in the daily diet , and reverse smoking by females , are factors believed to be responsible for high rates in the past . -
pubmed
This resulted in a reduced mineral concentration in the
fractures of treated
rats compared to controls in the last part of the experiment . -
pubmed
We describe three
patients with
HG who also had
Graves ' disease , and , in addition , one of these patients had
alopecia totalis and
ulcerative colitis . -
pubmed
Effect of
vitamin B2 on
tumorigenesis of
3 - methylcholanthrene in the
mouse skin . -
pubmed
Local administration of
riboflavin 2 ' , 3 ' , 4 ' , 5 '- tetrabutyrate (
B2 - But4 ) suppressed the induction of
skin tumors in
mice by
3 - methylcholanthrene . -
pubmed
Aspirin effect on
cataract formation in
patients with
rheumatoid arthritis alone or combined with
diabetes . -
pubmed
The prevalence of
cataracts is significantly lower in
patients with
rheumatoid arthritis receiving
aspirin ( mean of 2,700 mgs daily for an average of 10.4 years ) as compared to the matched population not receiving
aspirin . -
pubmed
A study was made of the incidence of
postoperative endocarditis and of
septicaemia in early
convalescence in 814 consecutive
patients undergoing open - heart surgery . -
pubmed
Preclinical studies in the laboratory and in
animals now suggest the feasibility of investigating such an agent in the targeted therapy of
patients with
human breast cancer . -
pubmed
In
rats , physical correlates have been characterized as intense
hyperactivity together with jumping ,
ptosis ,
teeth chattering , wet dog shakes , and
diarrhea . -
pubmed
METHOD : A consecutive series of 113 consenting
inpatients meeting DSM - III - R criteria for
schizophrenia ( 45 females , 68
males ) were assessed using reliable measures of
depression and negative symptoms . -
pubmed
Several experimental conditions were used in this study to evaluate the in vitro effects of
15 - deoxyspergualin on the function of T lymphocytes , B lymphocytes and monocytes from healthy subjects and
patients suffering from
systemic lupus erythematosus . -
pubmed
The subjects were 88
women aged 50 - 59 years ( including 32 with
fracture ) , 95
women aged 60 - 69 years ( including 54 with
fracture ) , and 34
women aged 70 - 79 years ( including 18 with
fracture ) . -
pubmed
Previous studies of regional differences in myocardial deformation between the anterior and posterior walls of the
canine left ventricle were based on
strain , which is not an absolute measure of deformation . -
pubmed
Raising at thermoneutrality prevents
obesity and
hyperphagia in BAT - ablated transgenic
mice . -
pubmed
A deficit in energy expenditure for brown adipose tissue ( BAT ) thermogenesis in these
mice is presumed to contribute to the development of
obesity . -
pubmed
The objective of the present study was to obviate any deficit in BAT thermogenesis by raising transgenic and control
mice at thermoneutrality ( 35 degrees C ) , where both would have equally inactive BAT , to see whether this would prevent the
obesity and the
hyperphagia . -
pubmed
As seen before , transgenic
mice raised at 24 degrees C had excess
weight gain by 6 wk of age and by 8 wk had doubled carcass fat , an
obesity characterized by increased white adipocyte size with no increase in number of adipocytes . -
pubmed
UCP - DTA
mice thus differ from genetically
obese mice ( ob / ob , db / db ) for which raising at thermoneutrality is known not to prevent either the
obesity or the
hyperphagia . -
pubmed
The sequence revealed that this isolate was a type-1
ADV strain , supporting that the currently used typing of
ADV viruses does not correlate with virulence or pathogenicity . -
pubmed
ADV - SL3 had a very high overall homology of 99.5 % to the prototype
strain ADV - G at the DNA level . -
pubmed
Comparative sequence analyses with various
ADV isolates of known virulence did not reveal a consensus sequence that could obviously be responsible for the apparently unique biological properties of this virus
strain . -
pubmed
In a double - blind , parallel - group study , we examined the effect of short - term treatment with inhaled
fluticasone propionate (
FP ) in a group of 20 nonsmoking
asthmatic patients who required only beta2 - agonists to control their symptoms . -
pubmed
When sand
rats are transferred from their natural desert environment and placed on a laboratory chow diet , they become
overweight , develop
hypertriglyceridaemia ,
hypercholesterolaemia , become
insulin resistant , and ultimately
diabetic . -
pubmed
In the present study
glucose intolerant animals , with very mild if any
hyperglycaemia were used . -
pubmed
These data confirm in another
animal model the therapeutic benefits of
S15261 in
insulin resistant states . -
pubmed
In conclusion , the clinical presentation of
acute hepatitis C is generally mild in chronic haemodialysis
patients , but spontaneous resolution is infrequent . -
pubmed
Inhaled anticholinergics are particularly useful in
patients with
COPD and in the future long - acting drugs , such as
tiotropium bromide , will be available . -
pubmed
Inhaled glucocorticoids are the most effective therapy in controlling
chronic asthma symptoms , and systemic effects are not a problem in the vast majority of
patients . -
pubmed
METHODS : An 11 - year - old
boy had an 8 - year history of diffuse
conjunctival papillomas , treated previously with standard measures of excisional biopsy and cryotherapy . -
pubmed
gene transfer at day 15 of gestation in a
murine model of
hemophilia A. -
pubmed
METHODS : The
patients selected had unequivocal evidence of
H. - pubmed
B - lymphotropic viruses in a novel
tropical splenic lymphoma . -
pubmed
However ,
lymphoma patients had markedly raised
EBV antibody levels without a concomitant increase in the rate of detection of viral genomes in the peripheral blood . -
pubmed
Photoirradiation of
mice at various times after injection indicated there was no correlation between
photosensitivity and immunosuppression . -
pubmed
Infusion of
methylene blue in
human septic shock : a pilot , randomized , controlled study . -
pubmed
PATIENTS : Twenty
patients with
septic shock diagnosed & lt;24 hrs before randomization . -
pubmed
CONCLUSIONS : In
human septic shock , continuously infused MB counteracts
myocardial depression , maintains
oxygen transport , and reduces concurrent adrenergic support . -
pubmed
Our aim was to assess the contribution of
hydroxyl radicals to early neuropathic changes by examining the effects of treatment with the specific scavenger ,
dimethylthiourea , on nerve function and neural tissue blood flow in
diabetic rats . -
pubmed
CONCLUSION / INTERPRETATION :
Hydroxyl radicals seem to make a major contribution to
neuropathy and
vasculopathy in
diabetic rats . -
pubmed
The data suggest that the development of potent
hydroxyl radical scavengers suitable for use in
man could markedly enhance the potential therapeutic value of an antioxidant approach to the treatment of
diabetic neuropathy and
vascular disease . -
pubmed
A case of
SCC of the pleura in a 66 - year - old
man with pre - existent asbestos - related
pleural plaques is presented . -
pubmed
This is the first case of
pleural SCC in a
patient with
asbestos - induced
pleural disease and the third reported case of a
pleural SCC . -
pubmed
The
SCC developed in an area with pre - existent pleural thickening , underlining the need for careful analysis of alterations in the manifestation of
pleural disease in
patients with asbestos exposition . -
pubmed
METHODS : All 40
skeletal Class III malocclusion patients we analyzed were from joint clinic of our hospital . -
pubmed
After presurgical orthodontic treatment , most of the
patients could be treated by one piece surgery , which could simplify the surgical procedure and reduce the
relapse rate of surgery . -
pubmed
Human defensive behaviors to threat scenarios show parallels to fear- and
anxiety - related defense patterns of non -
human mammals . -
pubmed
REE , though slightly elevated compared to healthy children ( baseline 106%+/-8 % predicted ) , remained stable throughout the study and at a level which may be expected for
children with minimal
lung disease . -
pubmed
CONCLUSIONS : In summary , these pilot data from younger
children with milder CF - related
lung disease do not confirm anecdotal reports of improved rate of
weight gain , caloric intake or decreases in the elevated REE . -
pubmed
Defective
calcium (
Ca ( 2 + ) ) signaling , manifest as a loss of excitation - contraction ( EC ) coupling gain in cardiac muscle , likely plays an important role in the pathophysiology of
human heart failure . -
pubmed
Molecular pathogenesis of
human hepatocellular carcinoma . -
pubmed
BACKGROUND : There is no standard treatment for
patients with infected
abdominal aortic aneurysm (
AAA ) . -
pubmed
To determine the basis for selection of a surgical method , we reviewed our experiences with all
patients who underwent surgery for infected infrarenal
AAA . -
pubmed
METHODS : Between 1993 and 2000 , 6
patients with infected infrarenal
AAA underwent surgery . -
pubmed
Extra - anatomic bypass grafting was performed in 2 of 3
patients with
infection extending into the retroperitoneum . -
pubmed
In situ grafting was performed in 3
patients with localized
infection and in 1
patient with extended
infection . -
pubmed
RESULTS : Severe
peritonitis occurred in 2
patients with extended
infection in the early postoperative phase . -
pubmed
One
patient , who had undergone in situ grafting , died of
sepsis . -
pubmed
For a
patient with extended
infection , postoperative continuous irrigation with ESAAS appears to be effective in eradicating
retroperitoneal infection . -
pubmed
Effectiveness of the anger - control program in reducing anger expression in
patients with
schizophrenia . -
pubmed
The purpose of this study was to evaluate the anger control program in reducing anger expression in
patients with
schizophrenia . -
pubmed
The program was found to reduce anger expression in
patients with
schizophrenia effectively and to increase their anger control ability . -
pubmed
We have determined that the striatal dopaminergic
neurotoxicity observed in the
mouse is linked in some fashion to both body and environmental temperature . -
pubmed
An increase in
neurotoxicity was also apparent in
mice kept at an elevated temperature for only 5 or 9 h , but keeping
animals at 27 degrees C for 24 or 72 h was the most effective in increasing the
neurotoxicity of
d - METH . -
pubmed
MATERIAL : Sixty - five
adults ( 52
females , 13
males ) with a history of or still active
JCA were assessed an average of 26.7 years after disease onset . -
pubmed
RESULTS : Evidence of ocular complications was found in 13
subjects ( 20 % ): 10 had had recurrent
iritis , two band
keratopathy , and one
diplopia due to
rheumatoid eye muscle involvement . -
pubmed
Binocularly , all but one
patient scored at least 6/9 as best corrected visual acuity ; one , however , had severe
glaucoma -
impaired visual fields . -
pubmed
CONCLUSION : Ophthalmic complications were recorded in 20 % of the study group , primarily in ANA positive
patients with pauciarticular onset
JCA . -
pubmed
In addition to the two
patients with severely affected bilateral visual status ( 3 % ) , one of the 65
patients had acquired unilateral
blindness . -
pubmed
HYPOTHESIS :
Patients who undergo laparoscopic refundoplication for postoperative intrathoracic wrap
herniation using a circular
polypropylene mesh for hiatal closure have a good to excellent functional outcome , during a complete follow - up of 1 year . -
pubmed
PATIENTS : Twenty - four
patients undergoing laparoscopic refundoplication for persistent or recurrent symptoms of
gastroesophageal reflux disease as a result of postoperative intrathoracic wrap migration . -
pubmed
In a prospective study on 57
patients with
venous ulceration we found significant lower
recurrence rates after mesh graft tissue transfer and radical surgical debridement . -
pubmed
[ Heat tolerance of
patients with
cardiac and vascular diseases under electric light baths ] . -
pubmed
The public health significance of
staphylococcic infection in
cattle . -
pubmed
[
Ammonia levels of
human blood following injection of
protein hydrolysates in relation to hepatic
coma ] . -
pubmed
OBJECTIVE : The goal of this study was to evaluate the clinical implications of integrating
human papillomavirus (
HPV ) testing into a long - term follow - up and management protocol for women postconization for high - grade
cervical intraepithelial neoplasia ( CIN2 - 3 ) . -
pubmed
Eleven ( 37.9 % ) had
high - grade cervical intraepithelial neoplasia or high - load
HPV results and were further treated by reconization / hysterectomy . -
pubmed
The respective positive predictive values of high - load
HPV and
low - grade squamous intraepithelial lesions were 100 and 60 % for any
CIN and 90 and 15 % for CIN2 - 3 . -
pubmed
OBJECTIVE : The purpose of this study was to determine which histologic features could enable one to distinguish
oral condyloma , as defined by the detection of
human papillomavirus (
HPV ) DNA through in situ hybridization , from its mimics . -
pubmed
STUDY DESIGN : Thirty - two paraffin - embedded specimens from 28
patients that were clinically suggestive of
oral condyloma were analyzed histologically and through in situ hybridization with a consensus
HPV probe . -
pubmed
The histologic features significantly associated with
HPV detection were nonuniform perinuclear halos , often in association with epithelial crevices ( P = .02 ) , and
papillomatosis ( P = .02 ) . -
pubmed
Each of the 17 patients who were
HPV - positive had either
HPV-6 or
HPV-11 , a finding that is similar to those for
condyloma involving the penis and vulva / vagina . -
pubmed
Bovine herpesvirus 4 (
BoHV-4 ) is a gammaherpesvirus with no clear disease association , it establishes persistent
infections in its natural host , the
bovine , and in an experimental host , the
rabbit . -
pubmed
METHODS AND MATERIALS : The study was performed in transplanted radiation - induced
fibrosarcoma tumors (
RIF-1 ) in 18 female
C3H / HEJ mice , which had two
lithium phthalocyanine (
LiPc ) deposits implanted in the
tumor when the
tumors reached about 200 - 600 mm(3 ) . -
pubmed
Clinicopathologic characteristics of 143
patients with synchronous bilateral invasive
breast carcinomas treated in a single institution . -
pubmed
METHODS : Between April 1997 and February 2003 , 143 consecutive
patients with
SBIBC were treated at the European Institute of Oncology ( Milan , Italy ) . -
pubmed
During the same time period , 6218
patients with unilateral invasive
breast carcinoma (
UIBC ) were analyzed in the same manner for comparison with the patients with
SBIBC . -
pubmed
A
tetraploid hybrid F2 population originating from a cross between a
Salix dasyclados clone ( SW901290 ) and a
Salix viminalis clone ( ' Jorunn ' ) was used in the study . -
pubmed
In two
patients conversion was necessary , one due to
bleeding of an earlier clipped lumbar artery after completion of the anastomosis , the other because of difficulties with the laparoscopic exposure of the aorta . -
pubmed
METHODS : In a retrospective study we surveyed 98 hospitalized malnourished
children ( ZW<--2 ) with no
chronic disease . -
pubmed
Diarrhea and/or
pneumonia were diagnosed at admission in 81.6 % of the
children . -
pubmed
To identify the diagnostic pitfalls as well as the value of immunohistochemical studies in making a pathologic evaluation of a pediatric
intestinal pseudo - obstruction (
IPO ) , this study reassessed the pathology of 87 surgically resected intestines from 80
patients under the impression of
IPO and 10 normal controls using immunohistochemical studies . -
pubmed
The final group was composed of eight
men and seven
women , each having one to seven chronic , stable
psoriatic plaques . -
pubmed
In a few
patients ,
blistering and burning sensation after some sessions were noted . -
pubmed
We also suggest
animal models and
human studies to test our hypothesis , the results of which may offer novel approaches in the prevention of
insulin resistance and
atherosclerosis . -
pubmed
METHODS : For this study , 28
patients with early
gastric cancers in the lower half of the stomach were randomly assigned to either LADG ( n = 4 ) or ODG ( n = 14 ) . -
pubmed
Gliomas represent the most frequent type of
human brain tumor , and their strong invasiveness is a significant clinical problem . -
pubmed
Patients were followed up for a minimum of one year or until
death . -
pubmed
Variability , regularity , and complexity of time series generated by
schizophrenic patients and control subjects . -
pubmed
We analyzed time series generated by 20
schizophrenic patients and 20 sex- and age - matched control subjects using three nonlinear methods of time series analysis as test statistics : central tendency measure ( CTM ) from the scatter plots of first differences of data , approximate entropy ( ApEn ) , and Lempel - Ziv ( LZ ) complexity . -
pubmed
RESULTS : Eighteen of 51
patients ( 35 % ) developed
HAMA following RIT ( range of ultimate maximum titers , 6.6 - 1,802 microg / ml ) . -
pubmed
Patients who undergo surgery in confirmed T3N1 stage are faced with 5 year survival period in 8%-10 % of the cases , emphasizing the fact that these
tumors are operable , but rarely curable by surgery itself . -
pubmed
Neo adjuvant therapy use is increasing for the
patients in stages IIB and IIC ( local progression of the
tumor ) , aiming to decrease the size of the primary
cancer prior to surgery thus increasing the rate of long term survival . -
pubmed
Our experiences brought out in this study correlate with the foreign results thus aging stressing the fact that the exact staging of the
tumor is the basics for the treatment as well as the right choice of the
patients for surgery treatment , and those who need neo adjuvant therapy . -
pubmed
Strains belonging to three novel yeast species ,
Candida heliconiae ( four isolates ) ,
Candida picinguabensis ( three isolates ) and
Candida saopaulonensis ( two isolates ) , were recovered in the year 2000 from water of flower bracts of
Heliconia velloziana L. Emigd . -
pubmed
The type
strains are
C. - pubmed
METHODS : Over a 24 - month period , 41
patients , including 20 with
hepatocellular cancer (
HCC ) , 14 with
liver metastases from colorectal
tumors and 7 with
metastases from other
tumors , underwent RFA in our institution . -
pubmed
Among 20
patients with
HCC , 16 had complete
tumor ablation and one had failure of localization . -
pubmed
All
patients with liver
metastases had successful
tumor ablation . -
pubmed
Two
patients had
hemoperitoneum and one experienced
skin burn . -
pubmed
During a median follow up of 16 months , five
patients with
HCC and two with
colorectal metastases died . -
pubmed
One
patient had
tumor recurrence at the ablation site and two developed fresh solitary
metastatic lesions ; all three are disease - free after repeat ablation treatment . -
pubmed
We examined whether the two most strongly associated variants ( rs12255372 and rs7903146 ) predict the progression to
diabetes in
persons with
impaired glucose tolerance who were enrolled in the Diabetes Prevention Program , in which lifestyle intervention or treatment with
metformin was compared with placebo . -
pubmed
Stress - induced
visceral hyperalgesia was abolished when
alosetron was injected intrathecally ( P<0.05 ) in intact
rats or subcutaneously ( 0.3 mg / kg ) in
capsaicin - pretreated
animals ( P<0.05 ) . -
pubmed
For prevention of lethal
arrhythmias ,
patients at risk receive implantable cardioverter - defibrillators , which use high - frequency antitachycardia pacing (
ATP ) to convert
tachycardias to a normal rhythm . -
pubmed
CLINICAL PRESENTATION : An 18 - year - old
girl presented with long - standing intermittent retro - orbital
pain and
oculomotor paresis . -
pubmed
Postoperatively , the
patient became
pain - free , and her oculomotor function partially recovered . -
pubmed
The study of
human skin irritation of a novel herbal skin care product and ingredients by
human single closed patch testing . -
pubmed
OBJECTIVE : Evaluate the
irritation potential of GPO products on
human skin using the single application closed patch test under occlusion . -
pubmed
The large - cell small - acinar
thyroid tumour of Langhans and the incidence of related cell groups in the
human thyroid . -
pubmed
We report the case of a
patient who received
DMSO - cryopreserved APBSC after myeloablative chemotherapy for a
relapsing lymphoma . -
pubmed
The
patient developed a rare reaction during the infusion manifesting as transient global
amnesia . -
pubmed
The present pilot study compared the ability of a conventional patient complaint - driven approach to that of nucleic - acid amplification testing ( NAAT ) of urine to identify those individuals among an adult , urban , Emergency Department ( ED ) population infected with
Chlamydia trachomatis (
CT ) ,
Neisseria gonorrhoeae ( NG ) , and
Trichomonas vaginalis ( TV ) . -
pubmed
Effect of polymer coating on faecal recovery of ingested
5 - amino salicylic acid in
patients with
ulcerative colitis . -
pubmed
To do so , three common times of virus inoculation were examined ( 0.5 , 4 , and 12 h ) along with two routes of inoculation ( immersion and
spot inoculation ) , and then two recovery methods were compared ( physical removal and chemical extraction / blending ) utilizing three different recovery eluents ( 2 % media ,
beef extract , and
phosphate - buffered saline ) . -
pubmed
In general , media containing 2 % fetal
bovine serum had more efficient recovery of the three viruses , and
spot inoculation was observed to be more efficient than inoculation by immersion . -
pubmed
RESULTS : The
liver cancer cell line
HepG2 was treated with essential oils from
Rosmarinus officinalis at various concentrations for different duration . -
pubmed
FQ is able to overcome the CQ resistance problem , an important limit to the control of
Plasmodium falciparum , the principal causative agent of
malaria . -
pubmed
RESULTS : Triple - negative
tumors occurred in 117 ( 18.9 % ) of the 620
patients , most often in association with invasive
ductal carcinomas . -
pubmed
Patients with triple - negative
tumors were younger than those with other receptor types , 44.5 % and 26.7 % , respectively , being diagnosed at age & lt;50 years ( P = 0.0004 ) . -
pubmed
[ Prevention and therapy of critical
ischemia in hemodialyzed
patients ] . -
pubmed
The
cardiovascular disease is largely increased in
chronic renal failure and the
patients have a 10 - 20 times higher mortality respect normal population . -
pubmed
In our experience appears that dialysed
patients present high total mortality and re - vascolarization ( particularly for
peripheral occlusive disease ) gives less guarantee of success . -
pubmed
MATERIALS AND METHODS : We retrospectively analyzed 118 consecutive case records of
patients admitted with acute
pancreatitis . -
pubmed
Forty - four
patients had a severe acute
necrotizing pancreatitis and only those were analyzed . -
pubmed
In this article , I argue that prevention of
cardiac dysfunction in
patients with lower grades of
MDS may not be the major benefit of
iron chelation therapy , and present evidence suggesting a potential benefit of
iron chelation on 3 other outcomes , namely ( 1 ) lowering
infection risk , ( 2 ) improving the outcome of allogeneic hematopoietic stem cell transplantation , and ( 3 ) delaying leukemic transformation . -
pubmed
These outcomes have particular relevance for
patients with higher grades of
MDS and should be evaluated in future prospective clinical trials that include
patients with all grades of
MDS to fully evaluate the benefit of
iron chelation therapy . -
pubmed
We have adduced strong evidence in favor of identifying the virus of Mexican
typhus fever with the Rickettsiae , or Mooser bodies , observed in the
tunica lesions of
Mexican typhus guinea pigs . -
pubmed
PARTICIPANTS : One hundred twenty - two
patients ( 126 eyes ) with
corneal diseases that were deemed ineligible to receive donor corneal transplants . -
pubmed
MAIN OUTCOME MEASURES : The medical records of the
patients were reviewed to assess intraoperative and
postoperative complications , uncorrected and best - corrected visual acuity , as well as the degree of
refractive error at various time points . -
pubmed
The mean spherical
refractive error was -0.57 diopters ( D ) and mean
astigmatism was 0.10 D. Cumulatively , 7.1 %
patients achieved their best - corrected vision at 1 day , 24.6 % at 1 week , and 70.6 % at 3 months . -
pubmed
The
patients who achieved their best - corrected visual acuity after the first 3 - month period most often were the ones who required multiple surgeries owing to preexisting or
postoperative complications . -
pubmed
CASE REPORT : We report a case of a 52 - year - old
woman , who presented with progressive
hearing loss and
fullness in the left ear for 3 months . -
pubmed
Follow - up of the
patient is essential in order to detect possible
recurrence . -
pubmed
Gingival enlargement in
children administered
cyclosporine after liver transplantation . -
pubmed
This study investigates the effects of
cyclosporine on the gingival tissues of liver - transplant pediatric
patients , determines the prevalence and severity of
gingival overgrowth , and analyzes the relationship between
gingival enlargement and possible risk factors . -
pubmed
METHODS : Twenty - five
children aged & lt;4 years old ( 15
males and 10
females ) with
end - stage liver disease , and awaiting liver transplantation were selected for this study . -
pubmed
RESULTS : The results show that the
cyclosporine - induced
gingival enlargement of these
children is not statistically associated with their age , gender ,
gingival inflammation , or serum level of
cyclosporine ( P & gt;0.05 ) . -
pubmed
CONCLUSIONS :
Children administered
cyclosporine after liver transplantation show that
gingival enlargement is statistically more related to the
plaque index than other factors such as age , gender ,
gingival inflammation , or the serum level of
cyclosporine , which suggests that
plaque control plays an important role in eliminating
gingival enlargement in
children who have undergone liver transplantation . -
pubmed
OBJECTIVE : Percutaneous radiofrequency ablation ( RFA ) has shown efficacy in
patients with recurrent
hepatocellular carcinoma , but has not been well documented in
patients with recurrent
intrahepatic cholangiocarcinoma (
ICC ) . -
pubmed
CONCLUSION : RFA is safe and provides successful local
tumor control in
patients with recurrent ICC after curative resection . -
pubmed
Skin vaccination against
cervical cancer associated
human papillomavirus with a novel micro - projection array in a
mouse model . -
pubmed
Here we investigate a novel dry - coated densely - packed micro - projection array skin patch ( Nanopatch ) as an alternate delivery system to intramuscular injection for delivering an alum adjuvanted
human papillomavirus (
HPV ) vaccine ( Gardasil ) commonly used as a prophylactic vaccine against
cervical cancer . -
pubmed
Myocardial
parvovirus B19 persistence : lack of association with clinicopathologic phenotype in adults with
heart failure . -
pubmed
Our studies do not support a causative role for
parvovirus B19 persistence in
HF and , therefore , advocate against the use of antiviral therapy for these patients . -
pubmed
Influence of
atorvastatin on the pharmacokinetics and pharmacodynamics of
glyburide in normal and
diabetic rats . -
pubmed
We have studied the effects of
atorvastatin on the pharmacodynamics and pharmacokinetics of
glyburide in experimental
diabetic rats . -
pubmed
was given to
alloxan - induced
diabetic rats for 7 consecutive days followed by
glyburide ( 10mg / kg p.o . ) -
pubmed
[ The impact of
tobacco smoking on oxidative stress parameters in the blood of normal
glucose tolerance persons and subjects with
pre - diabetes , separately ] . -
pubmed
MATERIAL AND METHODS : Caucasian
females and
males aged 35 - 64 , with no acute or severe
chronic disorder , taking no medication , special diet nor supplementation were enrolled to the study . -
pubmed
After receiving oral
glucose tolerance test results , newly diagnosed
type 2 diabetic subjects were excluded , and normal
glucose tolerance ( NGT ) and pre - diabetic (
PreDM )
persons underwent further investigation . -
pubmed
METHODS : A retrospective analysis of 52 consecutive
patients treated for infrarenal occlusive
aortic disease with primary stenting between January 2002 and November 2009 was performed . -
pubmed
Early surgical revision was necessary for
aortic rupture in 1
patient . -
pubmed
The
rats were exposed to a
hypoxia condition of 10 % for 0 , 2 , 12 , and 24 hr at sea level . -
pubmed
Some
human embryonic stem cell lines have shown
genomic instabilities over long - term culture . -
pubmed
Although the use of peritoneovenous shunts for intractable
ascites has been reported previously , our cases differ in both technique and
patient size . -
pubmed
Our first
patient is an ex-28 - week premature , 1.4 - kg infant with intractable
ascites for which a peritoneal drain was initially placed . -
pubmed
The second
patient was 5 months old , 2.8 kg , with a course complicated by
necrotizing enterocolitis , prolonged total parenteral nutrition , and progressive
liver failure and underwent the same procedure . -
pubmed
Both
patients had dramatic responses to the shunting postoperatively , with clinical , radiographic , and laboratory evidence of resolution of the
ascites . -
pubmed
The first
patient had the shunt removed at 6 months of age and continues to do well , whereas our second patient had no
recurrence of the
ascites , but died about 1 year later from cardiopulmonary complications . -
pubmed
STUDY DESIGN & amp ; SETTING : Cross - sectional study of ambulatory
individuals with prevalent
cardiovascular disease . -
pubmed
the area of breast including the primary
tumor bed and the surrounding tissue ) using 3D - CRT with
patients in prone position . -
pubmed
Poor sleep quality is associated with
depressive symptoms in
patients with
heart disease . -
pubmed
BACKGROUND :
Depression in cardiac
patients has gained importance due to increased mortality . -
pubmed
PURPOSE : This cross - sectional study aims to examine
sleep disturbances and
depressive symptoms in consecutively admitted cardiac
patients and depressed
patients . -
pubmed
METHODS : Two hundred four
inpatients ( 113
male , 91 female ) were examined : 94 cardiac
inpatients ( mean age 49.3 + - 14.3 years ) with different
heart diseases and 110
psychiatric inpatients ( mean age 41.6 + - 13.0 years ) with
depressive disorders (
DP ) . -
pubmed
A
depressive episode according to International Classification of Diseases ( ICD)-10 was also diagnosed in 14 of the cardiac
patients ( DCP ) . -
pubmed
This study investigated the posterior movement of the spinal cord after posterior decompression surgery and evaluated factors affecting postoperative functional recovery in
patients with
cervical spondylotic myelopathy (
CSM ) . -
pubmed
MATERIAL AND METHODS : Endomyocardial biopsy was performed in 195
IDCM patients , and five to six specimens were collected from the left ventricle . -
pubmed
Autonomic ganglionated plexi : characterization and effect of epicardial microwave ablation in a
canine model of vagally induced acute
atrial fibrillation . -
pubmed
METHODS : : 8 Mongrel
dogs ( 25 - 31 kg ) , underwent cervical vagal trunk stimulation to produce
AV nodal block and sustained
AF . -
pubmed
RESULTS : : Baseline cervical vagal stimulation produced
AV block and
AF in all the
animals . -
pubmed
We aimed to evaluate the surgical indication , especially for the
patients with concomitant multiple
liver metastases or extreme local invasions . -
pubmed
METHODOLOGY : The overall survival ( OS ) and the
disease free survival ( DFS ) were statistically analyzed for twenty one
patients with
PNETs who underwent surgical intervention in our institute . -
pubmed
CONCLUSIONS : Appropriate radical operation with multi - disciplinary treatments could contribute to the
patients ' survival in the treatment strategy of
PNETs . -
pubmed
[ Bariatric surgery in a
patient with
adipositas permagna and uncontrolled
insulin resistance ] . -
pubmed
HISTORY AND ADMISSION FINDINGS : A 58 - year - old
patient had a 21 years history of
diabetes mellitus and multiple
diabetic complications . -
pubmed
The treatment improved the
patient 's quality of life , optimized metabolic control and resulted last but not least in lower costs for the
diabetes treatment . -
pubmed
[ Perineal urethrostomy plus secondary urethroplasty for ultralong
urethral stricture : clinical outcomes and influence on the
patient 's quality of life ] . -
pubmed
OBJECTIVE : To investigate the outcomes of perineal urethrostomy plus secondary urethroplasty for ultralong
urethral stricture and assess its influence on the
patient 's quality of life . -
pubmed
The mean age of the
patients was 40 years , and the average length of
stricture was 6.5 cm . -
pubmed
We evaluated the patients'quality of life by questionnaire investigation and the clinical outcomes based on IPSS , Qmax , the necessity of
urethral dilation and satisfaction of the
patients . -
pubmed
CONCLUSION : Perineal urethrostomy plus secondary urethroplasty is safe and effective for ultralong
urethral stricture , and affects very little the
patient 's quality of life . -
pubmed
Neurodevelopmental outcomes in
children with
Angelman syndrome after 1 year of behavioural intervention . -
pubmed
OBJECTIVE : To examine the impact of teaching approaches based on the principles of applied behaviour analysis ( ABA ) on neurodevelopmental outcomes in
children with
Angelman syndrome (
AS ) . -
pubmed
The intervention group consisted of four
children with
AS aged 3.1 - 9.2 years . -
pubmed
Controls were other
children with
AS who were individually matched on the basis of chronological age , gender and molecular sub - type . -
pubmed
CONCLUSION :
ABA - based intervention improved aspects of neurodevelopment for some
children with
AS and warrants further study . -
pubmed
We aimed to determine whether the use of a 3 - step critical pathway is safe and effective in reducing duration of intravenous antibiotic therapy and length of stay in hospitalized
patients with
CAP . -
pubmed
Secondary end points were the duration of intravenous antibiotic therapy ,
adverse drug reactions , need for readmission , overall case - fatality rate , and
patients ' satisfaction . -
pubmed
More
patients assigned to usual care experienced
adverse drug reactions ( 4.5 % vs 15.9 % [ difference , -11.4 percentage points ; 95 % CI , -17.2 to -5.6 percentage points ; P & lt ; .001 ] ) . -
pubmed
CONCLUSIONS : The use of a 3 - step critical pathway was safe and effective in reducing the duration of intravenous antibiotic therapy and LOS for
CAP and did not adversely affect
patient outcomes . -
pubmed
Such a strategy will help optimize the process of care of hospitalized
patients with
CAP , and hospital costs would be reduced . -
pubmed
Evaluation of the hepatoprotective Effects of
Lantadene A , a
pentacyclic triterpenoid of
Lantana plants against
acetaminophen - induced
liver damage . -
pubmed
The aim of the present study was to evaluate the hepatoprotective activity of
lantadene A against
acetaminophen - induced
liver toxicity in
mice was studied . -
pubmed
RESULTS : Among the 93
PCG patients whose sex was recorded , 57 were male ( 61.3 % ) and 36 were female ( 38.7 % ) ( P=0.03 ) . -
pubmed
Compared with wild - type
mice , the miR21 deletion in ECs resulted in structural and functional remodeling of aorta significantly , such as
diastolic pressure dropping , maximal tension
depression , endothelium - dependent relaxation impairment , an increase of opening angles and wall - thickness / inner diameter ratio , and compliance decrease , in the miR21 endothelial - specific knockout
mice . -
pubmed
Modeling
hepatic osteodystrophy in
Abcb4 deficient mice . -
pubmed
Hepatic osteodystrophy (
HOD ) denotes the alterations in bone morphology and metabolism frequently observed in
patients with
chronic liver diseases , in particular in case of
cholestatic conditions . -
pubmed
METHODS : CNAs in
tumor DNA samples from 125
patients in the discovery cohort who underwent prostatectomy were assayed with high - resolution Affymetrix 6.0 single - nucleotide polymorphism microarrays and then analyzed using the Genomic Identification of Significant Targets in
Cancer ( GISTIC ) algorithm . -
pubmed
Based on modern cell ,
animal , and
human studies ,
piperine has been found to have immunomodulatory , anti - oxidant , anti - asthmatic , anti - carcinogenic , anti - inflammatory , anti -
ulcer , and anti - amoebic properties . -
pubmed
Although
neuronal migration disorder was not seen in our patient , this is the first
patient described with
haploinsufficiency of PDE1C possibly causing
developmental delay . -
pubmed
We evaluated the role of surgery followed by either chemotherapy ( ChT ) alone or chemotherapy and thoracic radiotherapy ( ChT / TRT ) versus sequential ChT / TRT in
patients with clinical stage I or
stage II small cell lung cancer (
SCLC ) . -
pubmed
Diffusion - Weighted Imaging in the Early Diagnosis of
EBV Meningoencephalitis . -
pubmed
DWI is a rapid
pulse sequence that must be added to the routine MR imaging regimen in
patients with suspected
meningoencephalitis . -
pubmed
INDICATIONS : Lateral unicompartmental
osteoarthritis of the knee with
genu valgum in young
patients . -
pubmed
POSTOPERATIVE MANAGEMENT : The
patient is mobilized under load with 20 kg
body weight for the first 6 postoperative weeks . -
pubmed
RESULTS : We treated 23
patients with
lateral cartilage damage ( grades 3 and 4 ) and
genu valgum with medial closing osteotomy of the distal femur ( 6 men and 17
women ) . -
pubmed
Individuals with this mutation ( likely with significantly increased levels of the hemoregulatory tetrapeptide in blood and tissues ) , may confer protection against
fibrosis . -
pubmed
Low - level laser therapy with 810 nm wavelength improves skin
wound healing in
rats with
streptozotocin - induced
diabetes . -
pubmed
OBJECTIVE : The aim of present study was to evaluate whether low - level laser therapy ( LLLT ) can reverse the impaired
wound healing process in
diabetic rats . -
pubmed
BACKGROUND DATA : Impaired
wound healing in
diabetic patients represents a major health problem . -
pubmed
Recent studies have indicated that LLLT may improve
wound healing in
diabetic rats , but the optimal treatment parameters are still unknown . -
pubmed
MATERIALS AND METHODS : Male
Sprague - Dawley rats ( n=21 ) were randomly divided into three groups : a healthy control group , a
diabetic sham - treated group , and a
diabetic LLLT - treated group . -
pubmed
RESULTS : In
diabetic rats , the histology of LLLT - treated excisions revealed a similar healing response to that in nondiabetic controls , with significantly more mature granulation tissue than in the sham - treated
diabetic control group . -
pubmed
LLLT reduced the loss of tensile strength , and increased the incision
wound stiffness significantly compared with sham - irradiated
rats , but this did not achieve the same level as in the nondiabetic controls . -
pubmed
CONCLUSIONS : Our study demonstrates that infrared LLLT can improve
wound healing in
diabetic rats . -
pubmed
Ultrasound - guided rectus sheath block or
wound infiltration in
children : a randomized blinded study of analgesia and
bupivacaine absorption . -
pubmed
OBJECTIVES : Compare the effectiveness and
bupivacaine absorption following USGRSB or
wound infiltration ( WI ) for
umbilical hernia repair in
children . -
pubmed
METHODS : A randomized blinded study comparing WI with USGRSB in 40
children undergoing
umbilical hernia repair was performed . -
pubmed
Induction chemotherapy - based larynx preservation protocols use chemotherapy to select exclusively
patients with ' chemosensitive '
tumors for a nonsurgical treatment with radiation therapy . -
pubmed
This study on
pyriform sinus squamous cell carcinoma (
SCC ) is interested in the oncological outcome of treatment based on radiation therapy when offered to
patients with
tumors responding to induction chemotherapy . -
pubmed
The role of
cats in the eco - epidemiology of
spotted fever group diseases . -
pubmed
BACKGROUND : Mediterranean Spotted Fever (
MSF ) , whose etiological agent is
R. - pubmed
Rickettsia felis , etiological agent of
Flea - borne spotted fever , is mainly transmitted by the
cat flea ,
Ctenocephalides felis . -
pubmed
Effects of probiotic yogurt consumption on lipid profile in
type 2 diabetic patients : A randomized controlled clinical trial . -
pubmed
The purpose of this study was to compare the effect of probiotic and conventional yogurt on lipid profile in
type 2 diabetes mellitus patients . -
pubmed
CONCLUSION : It is suggested that probiotic yogurt consumption may be used as an alternative prevention approach and treatment method to improve
dyslipidemia in
patients with
type 2 diabetes . -
pubmed
A 45 - year - old Chinese
man presented with a high
fever , urine occult blood , and a low density lesion in the right kidney . -
pubmed
Paraprotein interferences assays are known but rather unusual in clinical chemistry.we here report a paraprotein interference with a
bicarbonate assay in a
IgA kappa - type myeloma patient . -
pubmed
The
cryptococcal antigen lateral flow assay ( Immuno - Mycologics ) has revolutionized diagnosis of
cryptococcosis and automated nucleic acid amplification assays hold promise for improving diagnosis of
bacterial and mycobacterial meningitis . -
pubmed
Hesperetin , a
flavonoid from
citrus fruits , has been proved to possess biological activity on various types of
human cancers . -
pubmed
This article aims to provide a review on current issues related to the " locomotor " state and interactions between spinal and supraspinal influences on the central pattern generator ( CPG ) circuitry in
humans , which may be important for developing gait rehabilitation strategies in
individuals with
spinal cord and brain injuries . -
pubmed
In this study , we sought to evaluate the role played by this receptor during early and late stages of
infection with
Mycobacterium avium in
mice . -
pubmed
What Is the Clinical Utility of Bedside Ultrasonography in the Diagnosis of Acute
Cardiogenic Pulmonary Edema in the Undifferentiated Dyspneic
Patient ? -
pubmed
RESULTS :
Candiduria was detected in 146 catheterized in - patients out of the 1,408
patients included in this study . -
pubmed
Diabetes mellitus was associated with
C albicans candiduria . -
pubmed
The aim of this work was to explore the effect of
glycine on
endothelial dysfunction in aged
rats . -
pubmed
The
patients completed a clinical examination ,
Knee Injury and
Osteoarthritis Outcome Score ( KOOS ) and questionnaire evaluating QOL ( Eq5D-5L ) . -
pubmed
UNLABELLED : The present retrospective multicenter study analyzed the effect of perioperative blood transfusions ( PBTs ) on the outcomes in 285
patients with
upper tract urothelial carcinoma who had undergone radical nephroureterectomy ( RNU ) . -
pubmed
We found that
patients receiving PBTs had inferior survival compared with that of
patients without
PBTs . -
pubmed
BACKGROUND : Preoperative
anemia is an independent predictor for unfavorable outcomes in
patients with
upper tract urothelial carcinoma (
UTUC ) who undergo radical nephroureterectomy ( RNU ) . -
pubmed
We investigated the impact of PBT on the outcomes of
patients UTUC treated with RNU . -
pubmed
PATIENTS AND METHODS : We analyzed the data from 285
patients with
UTUC who had undergone RNU at 3 German academic institutions . -
pubmed
CONCLUSION : PBT is an independent risk factor for worse overall survival in
patients with
UTUC treated with RNU . -
pubmed
PURPOSE : To compare the clinical , microbiological and metabonomic profiles of
subjects with high and low levels of chronic
gingival bleeding during a controlled oral hygiene regimen intervention including sequential phases of rigorous therapeutic oral hygiene followed by experimental
gingivitis (
EG ) . -
pubmed
STUDY DESIGN : We performed a prospective two - armed cohort in a tertiary teaching hospital in Sao Paulo , Brazil , including 37 normotensive and 60 chronic
hypertensive pregnant
women . -
pubmed
RESULTS : Among normotensive and chronic
hypertensive pregnancies , 4 ( 10.8 % ) and 14 ( 23.3 % )
women developed
preeclampsia and superimposed
preeclampsia , respectively . -
pubmed
Human Trial of a Genetically Modified
Herpes Simplex Virus for Rapid Detection of Positive Peritoneal Cytology in the Staging of
Pancreatic Cancer . -
pubmed
INTRODUCTION :
Patients with peritoneal dissemination of
pancreatic adenocarcinoma do not benefit from surgical resection , but radiologic and cytologic detection of
peritoneal cancer lack sensitivity . -
pubmed
METHODS : Peritoneal washings from
patients with
pancreatic adenocarcinoma were incubated with the enhanced green fluorescent protein ( eGFP)-expressing oncolytic
herpes simplex virus ( HSV ) NV1066 . -
pubmed
These results were correlated with
recurrence and survival for
patients who underwent R0 resection . -
pubmed
HSV - mediated fluorescence detection had sensitivities of 94 % and 100 % for detection of any and
peritoneal metastatic disease ; respectively . -
pubmed
Median
recurrence free and disease specific survival were 6.5 and 18.3months for eGFP positive
patients , versus 12.2 and 36.2months for eGFP negative
patients ( P=0.01 and 0.19 ) ; respectively . -
pubmed
CONCLUSIONS : A genetically modified
HSV can be used as a highly sensitive diagnostic agent for detection of
micro - metastatic disease in
patients with
pancreatic adenocarcinoma and may improve
patient selection for surgery . -
pubmed
Primary
abscess of the iliopsoas muscle in children is uncommon , especially due to
Streptococcus pyogenes ( group A streptococcus :
GAS ) , which causes a variety of diseases ranging from
pharyngitis to invasive life - threatening
infection . -
pubmed
RESULTS :
TAC operation for 8 weeks produced a significant increase in left ventricular end - diastolic diameter and frequent occurrence of lethal
arrhythmias after infusion of
epinephrine and
caffeine in TAC
mice . -
pubmed
Fetal infection with
BVDV or
BoHV-1 occurred in 4/23 group A offspring , 0/22 group B offspring , and 15/15 group C offspring . -
pubmed
This research demonstrates efficacy of administering two pre - breeding doses of MLV vaccine with annual revaccination using CV vaccine to prevent
fetal loss due to exposure to
BVDV and
BoHV-1 . -
pubmed
[ Plasma and salivary markers of oxidative and
carbonyl stress in
patients with
acute intermittent porphyria ] . -
pubmed
The aim of our study was to investigate selected markers of oxidative and
carbonyl stress in plasma and saliva in
patients with
AIP and to find out whether saliva could be used for monitoring the disease progression . -
pubmed
METHODS : Blood and total non - stimulated saliva were collected from 16
patients with
AIP in remission , and from 20 healthy
individuals . -
pubmed
RESULTS : Advanced glycation end products and
thiobarbituric acid reacting substances in plasma and saliva were significantly higher in
patients with
AIP in comparison to the control group ( p & lt ; 0.001 ) and ( p & lt ; 0.05 ) . -
pubmed
CONCLUSIONS : According to the best of our knowledge this is the first study to demonstrate increased concentrations of markers of oxidative and
carbonyl stress and decreased antioxidant status of plasma and saliva in
patients with
AIP . -
pubmed
METHODS :
Patients presenting to hospital with acute
asthma were examined during the exacerbation , and after 4 weeks recovery . -
pubmed
RESULTS : Two male
patients aged 28 and 5 years presented with
MS with one
patient presenting with concomitant
AML . -
pubmed
Ocular Surface Parameters Predicting
Patient Satisfaction After a Single Vectored Thermal Pulsation Procedure for Management of Symptomatic
Meibomian Gland Dysfunction . -
pubmed
METHODS : This is a retrospective interventional case series ; it included consecutive
patients who underwent bilateral VTP for management of symptomatic
meibomian gland dysfunction (
MGD ) . -
pubmed
CONCLUSIONS : VTP can be effective in treating
dry eye symptoms of
patients with
MGD . -
pubmed
Our data show that objective findings of
dry eye , as evidenced by lower tear production , higher corneal and conjunctival staining scores , and higher osmolarity , tend to be markers present in the group of
patients responding positively to VTP . -
pubmed
Statin utilization improves oncologic and survival outcomes in
patients with
dyslipidemia and surgically treated
renal cell carcinoma . -
pubmed
BACKGROUND : We evaluated the role of statins in
patients who underwent surgery for
renal cell carcinoma (
RCC ) and who had
dyslipidemia , as use of statins has been suggested to improve outcomes in
RCC . -
pubmed
METHODS : Two - center retrospective study of
patients with
dyslipidemia who underwent surgery for
RCC from 7/1995 to 6/2005 . -
pubmed
CONCLUSIONS : In
RCC patients with
dyslipidemia , statin use was associated with improved survival outcomes , and was an independent predictor of PFS . -
pubmed
Further investigations are requisite to determine utility of statins in
RCC patients . -
pubmed
Matrix stiffness - induced reduction in unloaded shortening is more pronounced in cardiomyocytes isolated from obese ZSF1
rats with
heart failure with preserved ejection fraction compared to lean ZSF1
rats . -
pubmed
Additionally , cardiomyocytes isolated from stiff hearts of the obese ZSF1
rat model of
heart failure with preserved ejection fraction show more pronounced reduction in unloaded shortening in response to matrix stiffening . -
pubmed
This study aimed to explore the efficacy of 1 %
ALN gel as local drug delivery ( LDD ) in adjunct to scaling and root planing ( SRP ) for the treatment of
chronic periodontitis among
smokers . -
pubmed
Thus , 1 %
ALN , along with
SRP , is effective in the treatment of
chronic periodontitis in
smokers . -
pubmed
The miRNA expression profile GSE41268 was extracted from Gene Expression Omnibus database , and differentially expressed miRNAs between whole saliva samples from
patients with
EC and healthy controls were identified using the Linear Models for Microarray Data package . -
pubmed
A total of 18 differentially expressed miRNAs were identified in saliva samples from
patients with
EC , and 43 validated target genes corresponding to 7 upregulated miRNAs were identified . -
pubmed
BACKGROUND : Among other factors , like the time from
trauma to surgery or the number of axons that reach the muscle target , a
patient 's age might also impact the final results of brachial plexus surgery . -
pubmed
METHODS : Twenty pediatric
patients ( under age 20 yr ) who had sustained a traumatic
brachial plexus injury were compared against 20
patients , 20 to 29 yr old , and 20
patients , 30 yr old or older . -
pubmed
Univariate , univariate trend , and correlation analyses were conducted with
patient age , time to surgery , type of
injury , and number of injured roots included as independent variables . -
pubmed
METHODS AND ANALYSIS : In this randomised within -
patient controlled pilot trial , 20
patients with
hypertrophic CMs will be enrolled . -
pubmed
Among these
patients , 12
patients [ 4 with T - residual disease ( incomplete resection of primary
tumor but complete dissection of regional lymph node ) , 8 with N - residual disease ( complete resection of primary
tumor but incomplete resection of metastatic regional lymph node ) ] underwent 125I particle implantation during the operation , while the other 11 ( 4 with T - residual disease and 7 with N - residual disease ) received postoperative conventional radiotherapy . -
pubmed
However , there was no significant difference in the rates of
metastasis between the two groups for
patients with N - residual disease . -
pubmed
METHODS : We retrospectively reviewed 154 consecutive
patients who underwent cystectomy for
bladder cancer in two hospitals ( Hospital A and B ) between 2014 and 2016 . -
pubmed
The liver functions of the
patients reached normal levels before discharge and no additional
liver lesions were found upon diagnostic imaging . -
pubmed
This study encompasses the largest number of
HP patients to date , but the surgical outcomes require further research and long - term follow - up . -
pubmed
Our aim here was to examine the neurologic complications and our clinical experience in
patients who underwent liver transplant for
Wilson disease in our clinic . -
pubmed
MATERIALS AND METHODS : We retrospectively reviewed the medical records of transplant
patients with
Wilson disease who were seen at Baskent University Faculty of Medicine Transplantation Science between 2005 and 2017 . -
pubmed
Seven of 19
patients ( 36.8 % ) had
neurologic symptoms , including
epileptic seizures in 2
patients ( 10.5 % ) ,
encephalopathy in 1
patient ( 5.2 % ) ,
tremor in 3
patients ( 15.7 % ) , and
headache in 1
patient ( 5.2 % ) . -
pubmed
Patients with
epileptic seizures were provided with
seizure control medication (
levetiracetam ) . -
pubmed
The most common complication seen in our
patients was
tremor . -
pubmed
CONCLUSION : Targeted therapies are shifting the treatment paradigms and increasing survival for
patients with
PDAC , a group that used to have a grim prognosis . -
pubmed
Long - Term Effect of Pulsed Nd : YAG Laser in the Treatment of
Patients with
Rotator Cuff Tendinopathy : A Randomized Controlled Trial . -
pubmed
METHODS : Sixty
patients with
rotator cuff tendinopathy participated and completed the study . -
pubmed
CONCLUSIONS : Pulsed Nd : YAG laser combined with an exercise program seems to be more effective in the treatment of
patients with
rotator cuff tendinopathy than a sham laser with exercises . -
pubmed
The
patient was able to ambulate normally at a walk without
lameness four days postoperatively . -
pubmed
Findings were graded using several
neurologic impairment scales : two versions of the National Spina Bifida
Patient Registry ( NSBPR ) classification , the International Standards for Neurological Classification of
Spinal Cord Injury ( ISNCSCI ) motor level , and the Broughton
Neurologic Impairment Scale . -
pubmed
RESULTS : Data collected from 409
patient records showed significant correlations between Hoffer ambulation status and all
neurologic impairment scales evaluated . -
pubmed
AIMS / INTRODUCTION :
Metformin , a widely prescribed antidiabetic agent , has been shown to exhibit anti - inflammatory effects in obese and
type 2 diabetes patients , but the mechanism is not well elucidated . -
pubmed
All
patients are free of
disease after 53 months of median follow - up ( range : 8 - 94 ) . -
pubmed
BACKGROUND : Australia is committed to eliminating the
hepatitis C virus (
HCV ) by 2030 . -
pubmed
Among the risk factors assessed in this study , those responsible for the greatest decrease in under-5 LRI mortality between 1990 and 2017 were increased coverage of vaccination against Haemophilus
influenza type b ( 11 4 % decrease , 0 0 - 24 5 ) , increased
pneumococcal vaccine coverage ( 6 3 % decrease , 6 1 - 6 3 ) , and reductions in household air pollution ( 8 4 % , 6 8 - 9 2 ) . -
pubmed
Data on genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from
hyperlipidemic mouse strains . -
pubmed
The data presented here are related to the research article , entitled Genetic linkage of oxidative stress with cardiometabolic traits in an intercross derived from
hyperlipidemic mouse strains , published in Atherosclerosis 2019 Dec 3;293:1 - 10 ( D. Fuller , A.T. Grainger , A. Manichaikul , W. Shi ) . -
pubmed
METHODS : In this pilot randomized controlled trial , twenty - eight
patients with diagnosed , bothersome
RLS were randomized to four treatment arms : no active intervention ( n = 7 ) , foot massager ( n = 8) , heat therapy ( n = 6 ) , and foot massager plus heat therapy ( n = 7 ) . -
pubmed
To our knowledge , this is the oldest individual with typical
parvovirus 19 - associated
PPGSS reported to date . -
pubmed
Comparison the effects of inhalation and massage aromatherapy with lavender and sweet orange on
fatigue in hemodialysis
patients : a randomized clinical trial . -
pubmed
The aim of this study was to compare the effects of inhalation and massage aromatherapy with lavender and sweet orange on
fatigue among hemodialysis
patients . -
pubmed
Conclusions Interventions with essential oils are effective in reducing
fatigue in hemodialysis
patients , although the effects of aromatherapy massage on
fatigue are stronger than the effects of inhalation aromatherapy . -
pubmed
There was one intra - operative
pneumothorax , and two
patients with superficial malignant
tumours developed
skin ulcerations . -
pubmed
Objectives : To report the management of three consecutive
patients with relapsing
Staphylococcus aureus prosthetic knee infection (
PKI ) for whom explantation was not feasible who received a phage therapy during a " Debridement Antibiotics and Implant Retention " ( DAIR ) procedure followed by suppressive antimicrobial therapy . -
pubmed
During surgery , all
patients had poor local conditions including
pus in contact to the implant . -
pubmed
After a prolonged follow - up , mild discharge of synovial fluid persisted in two
patients , for whom a subsequent DAIR was performed showing only mild
synovial inflammation without bacterial persistence or super -
infection . -
pubmed
ABSTRACT :
Neuropathic pain (
NeuP ) can be difficult to diagnose and manage in
children . -
pubmed
This observational cohort study recruited
adolescents ( 10 - 17years ) with
NeuP or
complex regional pain syndrome (
CRPS ) . -
pubmed
Background : To describe a clinical case of a
cancer patient who underwent ablative
tumor surgery , including treatment planning , surgical resection and subsequent implant rehabilitation . -
pubmed
Case Report : A 61 - year - old
patient with a diagnosis of
multicystic follicular ameloblastoma in the maxilla , in which it was necessary a multidisciplinary approach and two surgical steps . -
pubmed
Computed Tomography Angiography for the Diagnosis of
Coronary Artery Disease Among
Patients Undergoing Transcatheter Aortic Valve Implantation . -
pubmed
At
patient level , NPV for significant
CAD was 88.6 % . -
pubmed
CONCLUSION : Pre - TAVI CTA shows good performance for ruling out
CAD and could be used as a gatekeeper for ICA in selected
patients . -
pubmed
Dual veno - arterial extra - corporeal membrane oxygenation support in a
patient with refractory hyperdynamic
septic shock : a case report . -
pubmed
The hypodynamic
septic shock appears to be a promising indication to veno - arterial membrane oxygenation ( VA - ECMO ) support of a
patient with
insufficient cardiac output . -
pubmed
With cardiac recovery most of those
patients progress into a hyperdynamic
septic shock with cardiac output , which may not match critically low systemic vascular resistance to maintain perfusion pressures . -
pubmed
We report a rare case of a 27 - year old
patient who developed severe refractory hypodynamic
septic shock due to the bilateral
staphylococcal pneumonia and had to be initially rescued by femoro - femoral VA - ECMO . -
pubmed
Treatment with
streptokinase or
heparin was allocated randomly to 20
patients with major
pulmonary embolism verified by angiography . -
pubmed
In the
heparin group , 1
patient died from massive
embolism 15 hours after the start of treatment . -
pubmed
In another
patient who died 4 weeks later from
cerebral glibolastoma , persistent massive
embolism contributed to the fatal outcome . -
pubmed
Plasma levels were measured at different times during long - term
flunarizine treatment ( duration 1 - -45 months , median : 6 months ) of 50
patients with
intermittent claudication . -
pubmed
The dialysate composition can be modified for the treatment of
patients with
acute renal failure . -
pubmed
The effects of acutely induced
metabolic and respiratory alkalosis with reduction of serum
potassium concentration as well as chronic total body
potassium depletion induced by
furosemide treatment were evaluated and correlated with alteration of
neuromuscular blockade induced by
d - tubocurarine ,
pancuronium , and
succinylcholine in 12
mongrel dogs . -
pubmed
[ Granulocyte transfusion in the treatment of
infections in
patients with
granulocytopenia ] . -
pubmed
Implications of the monoclonal character of
human atherosclerotic plaques . -
pubmed
The evidence for the monoclonal nature of
human atherosclerotic plaques is briefly reviewed . -
pubmed
If we assume then that there is reason to accept the monoclonal character of
atherosclerotic plaques in
human beings then we are led to a search for the presence of factors that could " initiate " the monoclonal proliferation as well as factors that may promote the growth of the plaques . -
pubmed
[ Effect of immunosuppressive agents on the dynamics of renal blood flow in
patients with
collagen diseases ] . -
pubmed
Respiratory function tests ( forced vital capacity and forced expiratory volume in one second ) were performed serially in pregnancy , the puerperium , and at least six weeks post partum in 27
patients with a history of
asthma and in 12 control subjects . -
pubmed
The
subjects are 11
patients with
Parkinson ' s disease , 16 with
Shy - Drager syndrome (
SDS ) , 16 with
cerebellar cortical atrophy , 3 with
Machado - Joseph disease , 3 with
dentato - rubro - pallido - luysian atrophy and 2 with
Huntington ' s disease as well as 24 controls . -
pubmed
All
patients with
Parkinson ' s disease were administered
levodopa and
carbidopa . -
pubmed
Therapy of
infections in
mice irradiated in mixed neutron / photon fields and inflicted with
wound trauma : a review of current work . -
pubmed
To evaluate therapies for
sepsis in radiation casualties , we developed models of acquired and induced
bacterial infections in irradiated and irradiated - wounded
mice . -
pubmed
In all
mice , wounding after irradiation decreased resistance to
infection . -
pubmed
Therapy with
S - TDCM for
mice irradiated with either a mixed field or gamma rays increased resistance to
Klebsiella pneumoniae - induced
infections . -
pubmed
pneumoniae
infections in
mice exposed to a mixed radiation field or to gamma rays was more effective than single - agent therapy . -
pubmed
In all irradiated - wounded
mice , single therapy of acquired
infections with an antibiotic or
S - TDCM did not increase survival . -
pubmed
Survival of irradiated - wounded
mice after topical application of
gentamicin sulfate cream suggested that bacteria colonizing the
wound disseminated systemically in untreated irradiated
mice , resulting in
death from
sepsis . -
pubmed
In lethal models of acquired
infections in irradiated - wounded
mice , significant increases in survival were achieved when systemic treatments with
S - TDCM or
gentamicin were combined with topical treatments of
gentamicin cream . -
pubmed
Therapies for
sepsis in all
mice exposed to a mixed field were less effective than in
mice exposed to gamma rays . -
pubmed
Although it is well known that serious electrocardiographic abnormalities are not infrequently associated with
Duchenne ' s progressive muscular dystrophy (
DMD ) , there are few reports about pacing therapy for
patients with
muscular dystrophy . -
pubmed
Because the daily activity of
patients with rapidly progressive type of
muscular dystrophy such as
DMD is at a very low level , they do not require pacing therapy . -
pubmed
TERalb was examined in awake
Wistar rats with untreated
IDDM induced by
streptozocin infusion ( 65 mg / kg body wt i.v . ) -
pubmed
Blood volume remained unchanged ; however , systemic protein concentration increased from 4.9 + /- 0.1 g / dl in controls to 6.4 + /- 0.4 g / dl in 15 - day
IDDM rats . -
pubmed
Fifty
patients with
signs and symptoms of
chronic impingement syndrome and/or
rotator cuff tear were evaluated with shoulder arthrograms and ultrasonography . -
pubmed
Real - time ultrasonography is a diagnostically sensitive and specific noninvasive method to evaluate
patients with
shoulder impingement syndrome , leading to the recommendation that it be used as a primary imaging technique to obviate or supplement arthrography in evaluating
rotator cuff disease . -
pubmed
Clinical examination of
heparin - Ca in
myocardial infarction patients . -
pubmed
25,000 IU / ml , Chemical Works of Gedeon Richter ) has been examined in 26 acute and 6 imminent
myocardial infarction patients . -
pubmed
Ten healthy
male volunteers and 19 hospital
patients ( 14
males and 5 females ) with
lung tuberculosis cooperated for this investigations . -
pubmed
Effect of dietary
selenium and
tumor status on the retention of
75Se by tissues and
mammary tumors of
DMBA - treated
rats . -
pubmed
The effects of the presence of
mammary tumors on
75Se retention was examined in
DMBA - treated
rats . -
pubmed
Tumor bearing
rats fed varying amounts of
Se exhibited an inverse linear dose response between dietary
Se intake and tissue retention of
75Se in whole body , heart , lungs , ovaries , adrenals , spleen , and muscle . -
pubmed
Tumor bearing
rats excreted more 75
Se label in the urine compared to both control
rats fed the same amount of
Se and
DMBA - treated
animals that remained
tumor free . -
pubmed
By 7 d , the increased urinary excretion of the label resulted in significantly decreased retention of
75Se in blood , spleen , liver , lungs , and kidneys of
tumor - bearing
rats compared to
tumor - free
animals . -
pubmed
These results suggest that
tumor bearing
animals have an accelerated urinary excretion of
Se compared to animals without
tumors and that
tumors either have a very slow turnover of
Se or a low priority for the element . -
pubmed
ACFID is indicated for
radiculopathy due to both soft and hard discs and can be particularly valuable in treating
patients with
disc herniation adjacent to a previous fusion or
radiculopathy with multiple - level myelographic filling defects . -
pubmed
Two hundred and nine consecutive
patients who suffered acute
trauma had their carpal scaphoids examined by a radiographic method comprising 4 oblique projections with 1.4 x magnification . -
pubmed
Lower rates of
thymidine incorporation into DNA of skin fibroblasts from
patients with
adenomatosis of the colon and rectum . -
pubmed
A total of six
chemodectomas of the carotid body or
ganglion nodosum in four
patients were treated with radiation therapy . -
pubmed
One
patient experienced complete regression of her bilateral
carotid body tumors over the ensuing 2.5 years and the other 3
patients have had no evidence of
disease progression of their
chemodectomas for 2 , 3 , and 4.5 years , respectively . -
pubmed
A study of a new compound with an original structure ,
teomorfolin [
N -( 7 '- theophylline acetyl ) morpholine ] , was performed in the
rat to investigate interaction with experimentally induced dislipidaemic disturbance related to
atherosclerotic disorders . -
pubmed
Effects of
Troxerutin on the hemorheological parameters of
patients with moderate
arterial hypertension . -
pubmed
Hypercholesterolemia and aortic glycosaminoglycans of
rabbits fed semi - purified diets containing
sucrose and
lactose . -
pubmed
The Gynecologic Oncology Group conducted a Phase II trial of
carboplatin in
patients with measurable advanced
squamous cell carcinoma of cervix . -
pubmed
Gastrointestinal toxicity was severe in three
patients ( 7.7 % ) . -
pubmed
Obliteration of peripancreatic fat planes usually is considered an indicator of peripancreatic
tumour infiltration in the presence of a malignant mass , or of
inflammation of peripancreatic tissues in
patients with
pancreatitis . -
pubmed
and a variety of phenotypic traits , production of several enzymes potentially involved in virulence ,
cytotoxicity for
Chinese hamster ovary cells , and
mouse lethality were unsuccessful . -
pubmed
One
patient treated with
clozapine ( 8 months ) and
nitrofurantoin ( 8 days ) developed a reversible
granulocytopenia . -
pubmed
One
patient ( treated with a combination of drugs ) had clinically insignificant
depression of the leucocytes and three of segmented granulocytes . -
pubmed
Two
patients developed
cardiac insufficiency , and four
epileptic seizures . -
pubmed
It is concluded that
clozapine is a potent antipsychotic drug offering particular advantages in the treatment of
schizophrenic patients with a pronounced symptomatology and tendency towards developing extrapyramidal side effects . -
pubmed
Caution is advised in
patients with
cardiac insufficiency and
epilepsy . -
pubmed
The association between
phosphocreatine 's antifibrillatory action and its effect on the excitement propagation processes in the ischemic area was investigated under acute
coronary arterial occlusion in
dogs . -
pubmed
[ Role of animals and birds as sources of
Salmonella infections in
man ( literature review ) ] . -
pubmed
[ Comparative study of fluorescent antibody indirect reactions in
Chagas ' disease ,
mucocutaneous leishmaniasis and kala - azar using various
Leishmania and Trypanosoma antigens ] . -
pubmed
Protocol for clinical therapeutic trials in
human breast cancer in advanced stages ] . -
pubmed
Field observation on the bionomics of
Leptotrombidium deliensis , the vector of
scrub typhus in the Pescadores . -
pubmed
[ Modification of morphologic structure of
human and
rat kidneys in
poisoning effects . -
pubmed
Ureteral pressure and its response to autonomic stimulations were investigated in paraplegics with
ureteral reflux and compared to the response in
patients with primary reflux , paraplegics without reflux , normal individuals and a
patient who had undergone lumbar sympathectomy . -
pubmed
The predominant organisms found in perinatal
infections were
Staphylococcus aureus ,
Group B streptococci and
Escherichia coli . -
pubmed
The majority of the hospital - acquired
infections was caused by Gram - positive cocci ( micrococci ,
Staph . - pubmed
Starvation of 300 g
rats for 3 days decreased ventricular - muscle
total protein content and total RNA content by 15 and 22 % respectively . -
pubmed
In
glucose - perfused working
rat hearts in vitro , 3 days of
starvation inhibited rates of protein synthesis in ventricles by about 40 - 50 % compared with fed controls . -
pubmed
We conclude that the rates of protein turnover in the anterogradely perfused
rat heart in vitro closely approximate to the rates in vivo in absolute terms , and that the effects of
starvation in vivo are mirrored in vitro . -
pubmed
The diagnostic value of bone scintigraphy in
patients with
low back pain . -
pubmed
Bone scintigraphy has been studied in two groups of
patients presenting with
low back pain . -
pubmed
In one group of 38
patients suffering " nonspecific "
back pain , bone scintigraphy and laboratory findings were negative in 24 . -
pubmed
By comparison , the bone scans were reviewed from another group of
patients suffering previously known
malignancy . -
pubmed
Out of 138
patients , nearly 40 % showed a positive bone scan due to subsequently proven
metastasis . -
pubmed
The present findings indicate that bone scintigraphy is not a useful procedure in
patients with long - standing
low back pain who have normal radiographs and normal laboratory findings . -
pubmed
The
murine mutation CatFraser causes a
cataract in both the mutant heterozygote ( C/+ ) and mutant homozygote ( C / C ) . -
pubmed
Specimens of
human breast tissues from the periphery of excised benign
tumors , obtained from 17 pre - menopausal
patients , were processed into slices and transplanted subcutaneously to 122 female
Balb / c athymic nude mice . -
pubmed
If the Columbian theory of origin of
syphilis were correct , the longer syphilization of the West Indies might have tended to lessen the effects of the disease by attenuating
Treponema pallidum . -
pubmed
Cystoid macular oedema in
aphakic patients . -
pubmed
Disturbance of recent memory function in
parkinsonian patients on anticholinergic therapy . -
pubmed
In this study the anticholinergic drug ,
trihexyphenidyl , at low doses when administered chronically for one month to
Parkinson disease patients caused a decrease in performance on recent but not immediate memory tests . -
pubmed
Awareness of possible
deterioration of memory function of
parkinsonian patients on anticholinergic medication is necessary . -
pubmed
The grim prognosis for
patients with severe
radiation injury of the intestine need not be considered unalterable . -
pubmed
Yersinia enterocolitica and
eye infection : a case report . -
pubmed
The authors reported a culturally proven case of
orbital cellulitis ,
uveitis and
conjunctivitis due to
Yersinia enterocolitica serotype 0:9 . -
pubmed
As the clinical parallelism , all
patients made a smooth
convalescence . -
pubmed
A double - blind study of 90
patients undergoing coronary angiography was performed to determine the safety and efficacy of 0.6 mg
atropine sulfate in preventing contrast - induced
bradycardia . -
pubmed
Coronary angiography performed using the Sones technique resulted in
ventricular pauses of greater than 2 seconds in 3 of 49
patients ( 6 % ) who received prophylactic
atropine and 20 of 41
patients ( 49 % ) receiving placebo . -
pubmed
To examine the basis of pulmonary constriction during chronic
hypoxia ,
rat pulmonary artery rings were precontracted and exposed to multiple episodes of
hypoxia . -
pubmed
Forty
subjects were clinically examined using scales for cerebellar , pyramidal ,
parkinsonian , and mental status and by quantitative evaluation of neuroimages . -
pubmed
The
patients were classified into two groups : cerebellar - plus and " pure "
cerebellar syndromes . -
pubmed
Patients with " pure "
cerebellar syndrome were diagnosed as
autosomal dominant cerebellar ataxia III (
ADCA III ) or " pure idiopathic " late - onset
cerebellar ataxia (
ILOCA ) in this series . -
pubmed
[
VM-26 plus
CCNU in the prevention of brain
metastasis in
lung cancer patients ] . -
pubmed
Brain
metastasis is of frequent occurrence in
patients with
cancer of the lung . -
pubmed
To ascertain if brain
metastasis is preventable , 34
lung cancer patients without
brain metastasis were treated with 4 cycles of
VM-26 plus
CCNU at 4 - week intervals . -
pubmed
As a control for comparison , an equal number of
lung cancer patients free of
brain metastasis were treated with chemotherapy protocol which did not include
VM-26 and
CCNU . -
pubmed
The results indicate that none of the
VM-26 plus
CCNU - treated
patients developed brain
metastasis while
brain metastasis occurred in 7 ( 20.5 % ) of 34 control
patients . -
pubmed
[ Vaccination of
cats against
infection with feline leukemia virus (
FeLV ): first recombinant vaccine and the effect of a pre - existing
infection with feline immunodeficiency virus (
FIV ) ] . -
pubmed
In order to determine the effect of a pre - existing
infection with
feline immunodeficiency virus on the efficacy of vaccination , 50 % of the
cats were previously infected with
FIV . -
pubmed
With prolonged duration of
FIV infection the probability increases , that the immune system of the
cat will fail and clinical signs will appear . -
pubmed
In order to observe a state of possible
immunodeficiency , an accurate clinical examination of every
cat prior to vaccination seems of major importance . -
pubmed
At the University of Pittsburgh Medical Center , four
patients have undergone single - lung transplantation for
lymphangioleiomyomatosis . -
pubmed
We report a 21 - year - old
man with
agammaglobulinemia and
chronic progressive encephalopathy . -
pubmed
Viral isolations were negative and serum antibody titers for
rubella ,
measles , and
human immune deficiency virus were not elevated . -
pubmed
Our patient 's symptoms resemble those previously reported as chronic progressive
encephalopathy without
viral isolation . -
pubmed
Patients present with localized
tenderness , induration , and
pain with passive flexion of the gluteal muscles . -
pubmed
The case history is presented of a
man in whom a
fistula between the oesophagus and left main bronchus was not diagnosed until the age of 48 . -
pubmed
To investigate this we measured
hypercapnic rebreathing responses in seven normal subjects ( six
males , age range 21 - 38 years ) with and without an inspiratory resistive load of 10 cm
H2O. -
pubmed
Seventeen
patients had
myocardial atrophy ,
fibrosis , or both . -
pubmed
Four ( 9.3 % ) of 43
patients without
myocardial atrophy or
fibrosis died as a consequence of other complications . -
pubmed
EXPERIMENTAL DESIGN : We used electroporation and lipofectin transfection to introduce various transforming constructs , and direct
infection with an oncogenic adeno 31 ( Ad31 ) virus to immortalize cells from freshly isolated
rat kidney glomeruli and characterized the cells obtained at their 20th , 40th , 60th , and 80th passage for markers of various glomerular cell types . -
pubmed
RESULTS : Direct
infection with an oncogenic
adenovirus type 31 ( Ad31 ) resulted in a stable cell line ( over 120 passages ) morphologically resembling epithelial / endothelial cells line ( over 120 passages ) morphologically resembling epithelial / endothelial cells . -
pubmed
Based on the reported sex difference in the incidence of
acquired cystic kidney disease (
ACKD ) in
patients with
chronic renal failure , it is hypothesized that the hormonal derangement , well documented in male and female
uremic patients on long - term dialysis , could be responsible for the pathogenesis of
ACKD . -
pubmed
Children with idiopathic congenital bilateral
vocal cord paralysis (
BVCP ) were investigated by electromyography ( EMG ) of the posterior cricoarytenoid and thyroarytenoid muscles to determine whether laryngeal EMG findings had diagnostic or prognostic significance . -
pubmed
We describe a
patient who developed a
vesicular eruption shortly after an irritant
dermatitis caused by the contact with a detergent containing
sodium hypochlorite . -
pubmed
We suggest a possible pathogenetic relationship between the
chemical dermatitis and
LABD in this
patient . -
pubmed
[
Neutropenic enterocolitis in
children with
cancer ] . -
pubmed
OBJECTIVES :
Neuropenic enterocolitis (
NEC ) is a destructive lesion of the ileocecal region occurring in
cancer patients treated with chemotherapy . -
pubmed
Our aim was to determine the incidence of
NEC in
children with
cancer and to review the indications of surgery in these cases . -
pubmed
MATERIAL AND METHODS : The records of
children with
cancer treated with chemotherapy in the last 6 years at Hospital Infantile La Paz were reviewed . -
pubmed
We selected those
patients who had
abdominal pain and
neutropenia and whose physical examination and radiological findings were consistent with
NEC . -
pubmed
CONCLUSION : Pediatric surgeons treating
neutropenic cancer patients should be familiar with this condition , that must be suspected early in granulocytopenic
patients with acute abdominal extension . -
pubmed
Preretinal neovascularization induced by experimental
retinal vein occlusion in
albino rats . -
pubmed
Retinal ischemia and neovascularization have been demonstrated in several
animal models . -
pubmed
To determine 1 ) whether the
retinal or preretinal neovascularization can be induced in albino
rats by
retinal vein occlusion and 2 ) the type and rate of occurrence on neovascularization , we occluded retinal veins in albino
rats by photodynamic
thrombosis . -
pubmed
These data suggest that
preretinal neovascularization in
albino rats can be induced by this minimally traumatic method and that
venous occlusion is severe enough to compromise arterial blood flow for a certain threshold period , thus inducing the development of
preretinal neovascularization . -
pubmed
We , therefore , examined the effects of upper airway negative pressure on reflex palatal muscle activity in 16 normal nonsnoring awake male subjects and 16 awake
SAHS patients using electromyography . -
pubmed
Reflex electromyographic response to negative pressure was reduced in
SAHS patients compared to normal subjects for both muscles ( p & lt ; 0.001 ) . -
pubmed
When the seven thinnest
SAHS patients were compared with seven normal subjects matched for
BMI and age , the
SAHS patients still demonstrated impaired responses to negative pressure for both muscles ( p & lt ; 0.001 ) . -
pubmed
That mutations in
human patched result in dysregulation of several genes known to play a role in both organogenesis and
carcinogenesis may explain both the
birth defects and the
cancer predisposition seen in the
nevoid basal cell carcinoma syndrome . -
pubmed
OBJECTIVE : To analyze the clinical features , management , and outcome of
patients with
Castleman disease . -
pubmed
PATIENTS : All
patients with
Castleman disease who were seen at Texas Medical Center , Houston , Texas , between 1977 and 1995 . -
pubmed
MEASUREMENTS :
Patients were identified according to initial presentation as having localized or multicentric
Castleman disease . -
pubmed
The 8
patients with multicentric disease were further subdivided according to initial treatment : Three
patients who received combination chemotherapy are currently alive and free of disease ; 2
patients treated with
prednisone are alive but have needed intermittent maintenance therapy for disease reactivations ; and 2
patients treated with surgery only have died , 1 of infectious complications and 1 of
non - Hodgkin lymphoma . -
pubmed
Sixty - seven
children aged 5 - 15 years were induced to
narcosis and narcotized with
diprivan . -
pubmed
The
patients were operated on for
appendicitis ,
peritonitis ,
osteomyelitis ,
phlegmons of different localization , and
craniocerebral injuries . -
pubmed
Cerebral ischemia after bilateral
carotid artery occlusion and intraluminal suture occlusion in
mice : evaluation of the patency of the posterior communicating artery . -
pubmed
Cerebral ischemia models using
mice have drawn increasing attention , particularly because of the availability of transgenic
animals . -
pubmed
However , the variability of intracranial vasculature at the circle of Willis in
mice can influence the degree of
ischemia in both the bilateral common carotid artery ( CCA ) occlusion and intraluminal suture occlusion models . -
pubmed
We have developed a method to predict the extent of the anastomosis between carotid and vertebrobasilar circulation in three
mouse strains ( C57BL/6 , CBA , and DBA/2 ) by measuring cortical microperfusion with laser Doppler flowmetry during a 1 - minute occlusion of both CCA . -
pubmed
When
animals showed residual cortical microperfusion of less than 12 % during bilateral CCA occlusion , the
mice showed absence of functional anastomosis , developed
ATP depletion in the frontal cortex during occlusion , and had ischemic neuronal
death in the hippocampus and caudoputamen after occlusion for 15 minutes and recirculation for 7 days . -
pubmed
Furthermore , those
mice exhibited decreased local cerebral blood flow and associated ischemic neuronal
death in the hippocampus , within the territory supplied by the posterior cerebral artery , with the intraluminal suture occlusion model . -
pubmed
The current study demonstrates the need for assessment of intracranial vasculature in each
animal by measuring cortical microperfusion during temporary occlusion of both CCA , no matter whether
cerebral ischemia is produced by bilateral CCA occlusion or intraluminal suture occlusion in transgenic
mice . -
pubmed
HIV-1 - induced perturbations of
glycosphingolipid metabolism are cell - specific and can be detected at early stages of
HIV-1 infection . -
pubmed
Rats were treated orally for 7 d with
dihydrotachysterol , which produced significant
hypercalcemia with a 15 + /- 2 % increase in plasma
calcium concentration . -
pubmed
Tuberculosis continues to be a worldwide problem for both
humans and animals . -
pubmed
The development of tests to differentiate between
infection with Mycobacterium tuberculosis or
Mycobacterium bovis and vaccination with
M. - pubmed
Iron loading produced by
TMH - ferrocene is highly efficient and , of the compounds used to produce
iron loading in experimental systems , most closely mimics the loading patterns observed in the
human disease
hemochromatosis . -
pubmed
The role of cranial MRI in identifying
patients suffering from
child abuse and presenting with unexplained neurological findings . -
pubmed
OBJECTIVE : The aim of this study was to demonstrate the usefulness of cerebral MRI to detect possible
child abuse in
children with unexplained
neurologic findings . -
pubmed
METHOD : Between 1990 and 1997 , 208
children were referred for suspected physical
child abuse to the Child Protection Clinic of Ste - Justine Hospital , a tertiary care pediatric hospital . -
pubmed
Human seminal plasma
protein allergy : a diagnosis rarely considered . -
pubmed
Women with
seminal plasma protein allergy (
SPPA ) have an immunologic response to
human semen . -
pubmed
Percutaneous transluminal coronary angioplasty is a routinely used non - surgical revascularization technique for
patients with
coronary artery disease . -
pubmed
Rabies is enzootic in raccoons (
Procyon lotor ) in the eastern United States . -
pubmed
Oral vaccination of free - ranging raccoons against
rabies has the potential to control the disease in a principal reservoir and reduce the risk of
rabies exposure among domestic animals and
humans . -
pubmed
Indications for filter placement were : recent
pulmonary embolism (
PE ) or proximal
deep vein thrombosis (
DVT ) with a contraindication to anticoagulation ( 11
patients ) , massive
PE treated with thrombolytic therapy ( one patient ) , PE with
heparin - induced
thrombocytopenia ( one
patient ) , and prophylaxis after
major trauma ( two
patients ) . -
pubmed
Patients were followed for
inferior vena cava ( IVC ) thrombosis ,
bleeding , and recurrent
DVT or
PE . -
pubmed
In order to understand the role of different glial cells in this process , we analysed the proliferation pattern of glial cells in central ( CNS ) and peripheral ( PNS ) parts of the dorsal root and the segmental white and grey spinal cord matter after dorsal rhizotomy or sciatic nerve transection in adult
rats 1 - 7 days after
injury . -
pubmed
BACKGROUND : Retrospective study in pediatric
patients with
Cornelia de Lange syndrome undergoing different surgical operations , in order to critically evaluate the anesthesiologic aspects of this
syndrome . -
pubmed
METHODS : Between January 1997 and December 1998 , 42
patients undergoing diagnostic examinations ( esophagogastroscopy , oculistic visit ) or surgery ( total
exodontia , fundoplicatio for
esophageal reflux , correction of
labiopalatoschisis ) have been studied . -
pubmed
CONCLUSIONS :
Short neck , ogive palatum ,
cleft palate ,
micrognatia , urogenital and
gastroenteric anomalies ,
esophageal reflux , together with
heart defects ( 15 % of cases ) , can complicate the peri and postoperative period in these
patients . -
pubmed
A careful preoperative evaluation and a careful perioperative management , may decrease anesthetic complications in
Cornelia de Lange syndrome to the same range of normal
patients . -
pubmed
Syncytium formation by
HSV-1 strain HF was inhibited , and small plaques with rounded cells were formed in
Conmy A - treated cell cultures . -
pubmed
METHODS : From 3320 pregnant
women who had delivered in our hospital and undergone the oral
glucose tolerance test for various risk factors over a three - year period , 163 with
alpha - thalassaemia trait were identified ( study group ) . -
pubmed
PURPOSE : We previously showed that
mitomycin C activity in
human bladder tumors is inversely related to
tumor stage and
muscle invasive tumors are less sensitive than
superficial tumors . -
pubmed
The perfusion of
human tumour xenografts was manipulated by administration of
diltiazem and
pentoxifylline , and the extent that observed changes in
tumour perfusion altered
tumour radiosensitivity was determined . -
pubmed
This study examines the incidence , predictors , and evolution of postoperative
atrioventricular block (
AVB ) after mitral valve repair ( MVR ) in 115 consecutive
patients using Carpentier 's technique ( between November 1996 and April 1997 ) . -
pubmed
Postoperative
AVB occurred in 27
patients ( 23 % ) . -
pubmed
Second - degree
AVB ( Mobitz type I ) occurred in 4
patients ( 3 % ) immediately after operation and resolved in all before hospital discharge . -
pubmed
Isolated first - degree
AVB occurred in 16
patients ( 14 % ) and was permanent in 12 . -
pubmed
Three
patients ( 2.6 % ) had permanent pacemaker implantation , on average 18 days after operation , and all had persistent third - degree
AVB . -
pubmed
Following
lesions were found :
hepatocellular carcinoma ( 5
patients ) ,
hemangioma ( 2 ) ,
metastasis ( 1 ) ,
cyst ( 1 ) ,
adenoma ( 1 ) . -
pubmed
METHODS : One hundred ninety - six consecutive
patients ( predominantly
teenagers ) previously unsuccessfully treated by surgery underwent
CO2 laser for recurrent
onychocryptosis . -
pubmed
One
patient developed a
neuroma in the lateral nail groove . -
pubmed
This may be seen in
patients with temporal lobe or other forms of
focal epilepsy , in the
epileptic encephalopathies such as
West and Lennox Gastaut Syndromes and even in some patients with
idiopathic generalized epilepsy . -
pubmed
Neuroimaging diagnostics of
cerebral hemorrhage in congenitally afibrinogenic
patients may be compromised by different pitfalls . -
pubmed
We describe the case of a 28 - year - old
patient with the diagnosis of
congenital afibrinogenemia who suffered a large
intracerebral hemorrhage . -
pubmed
Use of
Punica granatum as an antifungal agent against
candidosis associated with
denture stomatitis . -
pubmed
The aim of this study was to evaluate the use of a gel containing the extract of
Punica granatum as an antifungal agent against
candidosis associated with
denture stomatitis . -
pubmed
Sixty
patients with
denture stomatitis confirmed by clinical and mycologic examination were selected . -
pubmed
Participants were screened for
syphilis ,
chlamydia , and
gonorrhea and were also offered
HIV testing . -
pubmed
Of 2229 urine samples , 185 ( 8.3 % ) tested positive for
Chlamydia trachomatis and 108 ( 4.9 % ) positive for
Neisseria gonorrhoeae . -
pubmed
This study examined discourse ability in
children with
stroke as compared with orthopedic controls , age - at -
injury , and lesion effects . -
pubmed
[
Chronic cor pulmonale in
patients with
pulmonary fibrosis ] . -
pubmed
ISOLATING
PATIENTS WITH
STAPHYLOCOCCAL INFECTIONS . -
pubmed
Of the 1 113
strains , 66
strains were
influenza A - H1N1 , 544
strains were
influenza A - H3N2 viruses while 98 and 405
strains belonged to
B / Yamagata and
B / Victoria viruses with the rates of isolation on each subtype were 5.9 % , 48.9 % , 8.8 % and 36.4 % , respectively . -
pubmed
CONCLUSIONS : Although
influenza A subtype H1N1 and H3N2 as well as
B type viruses were co - circulating in our country , the
influenza A ( H3N2 ) and
B / Victoria isolates were found the predominant
strains in the period of this study which were different from the previous years . -
pubmed
Finally , PV
patients had higher oxidative burst and PNC than T - nPV
patients or
HC ( P & lt ; 0.05 ) . -
pubmed
CONCLUSION : Total glossectomy is an oncologically sound surgical procedure that should only be performed in carefully selected
patients with advanced
malignancies affecting the tongue . -
pubmed
Genes and mutations in
human idiopathic epilepsy . -
pubmed
Thirteen genes have already been identified in
human idiopathic epilepsies since 1995 , but they account only for a minority of all
epilepsy cases . -
pubmed
We recruited 50
men with advanced
prostate cancer who elected to receive hormonal therapy to be randomized to 1 of 3
flutamide treatment groups : 1 ) 250 mg once daily , 2 ) 250 mg twice daily , or 3 ) 250 mg 3 times daily for 3 months , after which the therapy of their choice was instituted . -
pubmed
Aberrant methylation of promoter
CpG islands in human genes is an alternative genetic inactivation mechanism that contributes to the development of
human tumors . -
pubmed
We report a
patient with
renal cell carcinoma who had an intracaval
tumor thrombus that had extended into the right spermatic vein . -
pubmed
This study quantified the influence of visual attention therapy on the reading comprehension of Grade 6
children with moderate
reading disabilities (
RD ) in the absence of specific reading remediation . -
pubmed
[ Endoscopic resection of
benign prostatic hyperplasia in
men over 80 years of age : a retrospective study of 184 cases ] . -
pubmed
OBJECTIVE : The aim of the present study was to evaluate the outcome of transurethral resection of the prostate for
benign prostatic hyperplasia in
men over 80 years . -
pubmed
MATERIAL AND METHOD : 184
men over 80 years underwent transurethral resection of the prostate for
benign prostatic hyperplasia . -
pubmed
CONCLUSION : Transurethral resection of the prostate for
benign prostatic hyperplasia in
men over 80 years has a good outcome with an acceptable morbidity and mortality . -
pubmed
Sera from newly diagnosed
type 1 diabetes patients ( n=61 ) were studied using both approaches . -
pubmed
A 44 - year - old
man presented with a rare
subfrontal schwannoma with
headache . -
pubmed
The
patient was discharged without
hyposmia . -
pubmed
A 30 - year - old white
man presented with a sporadic form of gradually progressive
spastic gait and , later ,
supranuclear vertical and horizontal gaze palsy , mild
cognitive impairment ,
loss of postural reflexes , and falls . -
pubmed
Treatment began at 6 weeks of age when
animals are
insulin resistant and hyperinsulinemic , but not yet
hyperglycemic , and ended at 12 weeks of age , which is 4 weeks after ZDF
rats typically develop overt
diabetes . -
pubmed
BMOV and
RSG treatment also prevented the hyper -
phagia and
polydipsia present in untreated ZDF
rats ; however ,
BMOV - treated ZDF
rats gained much less weight than did
RSG - treated
animals . -
pubmed
However , it is not fully understood whether and how
RXM suppresses angiogenesis in
human hepatoma , which is a well - known
hypervascular tumor . -
pubmed
MATERIALS AND METHODS : In the present study , we examined the effects of
RXM on
tumor angiogenesis in the
human hepatoma cell line ,
HepG2 . -
pubmed
Because
RXM is widely used in clinical practice , it may represent an effective new strategy for
human hepatoma therapy . -
pubmed
Leflunomide reduces
nitric oxide production in
patients with active
rheumatoid arthritis . -
pubmed
We carried out this study to determine if there was alteration in
NO production in
patients with
RA . -
pubmed
METHODS : An 8 - week open label study was carried out on
patients with adult onset active
RA . -
pubmed
RESULTS : Thirty - three
patients with active
RA were enrolled for this study . -
pubmed
CONCLUSIONS :
Leflunomide inhibits
nitric oxide production in
patients with active
RA . -
pubmed
The
inflammation in
cystic fibrosis (
CF )
patients with
chronic Pseudomonas aeruginosa lung infection is dominated by polymorphonuclear neutrophils ( PMNs ) . -
pubmed
The Norwegian Doloplus-2 , a tool for behavioural
pain assessment : translation and pilot - validation in nursing home
patients with
cognitive impairment . -
pubmed
BACKGROUND :
Pain assessment is challenging in cognitively impaired ( CI )
patients due to inadequate self - report skills and observational ratings are an alternative . -
pubmed
Femoral fractures are common in this
patient population , and management presents a unique technical challenge . -
pubmed
This case series describes the long - term management of nine
osteopetrotic femoral fractures in three
patients . -
pubmed
An unusual type of single
coronary artery anomaly in a
patient with
hypertrophic obstructive cardiomyopathy . -
pubmed
The basic process of reactive
astrocytosis is conserved in
vertebrate evolution , suggesting fitness - enhancing benefits , but
scar - forming reactive astrocytes are often regarded as uniformly detrimental to clinical outcome , in particular , when implicated as inhibitors of axon regeneration . -
pubmed
A seven - year - old
girl received intramuscular injection of
diclofenac for symptomatic treatment of her
fever . -
pubmed
Vitamin E and C supplementation prevents decrease of
eicosapentaenoic acid in mononuclear cells in
chronic hepatitis C patients during combination therapy of
interferon alpha-2b and
ribavirin . -
pubmed
First line treatment with beta - blockers followed by adjuvant
ACE inhibitors after six months may be safe in older
people with
heart failure . -
pubmed
CONCLUSIONS : The occurrence of
stroke in
patients with
atrial fibrillation is modestly higher during the winter . -
pubmed
Although serum
testosterone levels decrease acutely in
critically ill patients ,
estrogen levels rise . -
pubmed
Animal studies suggest that these opposing changes in circulating
estrogen and
androgen levels may be important to reduce morbidity and mortality in
critical illness . -
pubmed
Human colon adenocarcinoma cells (
HT29 - ATCC ) and the clone
HT29 - 5F7 were cultured under conditions that differentiate cells to a polarized intestinal phenotype . -
pubmed
Gargling with
tea catechin extracts for the prevention of
influenza infection in elderly nursing home residents : a prospective clinical study . -
pubmed
CASE REPORT : A 32 - year - old
man presented with severe upper
abdominal pain radiating to the back , associated with
vomiting and
abdominal distension . -
pubmed
The
patient was diagnosed as having had chronic
calcific pancreatitis recently and had undergone ERCP with pancreatic duct stenting elsewhere . -
pubmed
Two days after the procedure , the
patient developed severe
abdominal pain ,
vomiting and
abdominal distention , and
patient was referred to our hospital 7 days after the procedure . -
pubmed
This
patient had a life - threatening complication following pancreatic duct stenting for
chronic pancreatitis and was managed medically . -
pubmed
The Ts65Dn
mouse , a genetic model of
DS , exhibits phenotypes of
DS , including
memory impairments indicative of
hippocampal dysfunction . -
pubmed
[ The level of
cotinine - marker of
tobacco smoking , in
patients with
hyperthyroidism ] . -
pubmed
INTRODUCTION :
Orbitopathy associated with
Graves ' disease TAO (
thyroid associated orbitopathy ) is likewise connected with environmental factors including
tobacco smoking . -
pubmed
Tobacco smoking increases the risk of ophthalmologic pathology and leads to the orbital tissue damage due to the
hypoxia . -
pubmed
The aim of the study was to correlate the concentration of
urinecotinine ( marker of
tobacco smoking ) in
Graves ' disease patients with TAO with points received on the Fagerstrom questionnaire . -
pubmed
MATERIALS AND METHODS : Thirty
women with different degree of exacerbation of
TAO in
Graves ' disease ( 34.28 + /- 12.04 yr . ) -
pubmed
As control we used 29
women with
Graves ' disease without
TAO ( 29.35 + /- 12.33 yr . ) -
pubmed
In
patients with
Graves ' disease with
TAO the highest score of
tobacco smoking has been found in persons with the highest
ophthalmopathy exacerbation . -
pubmed
None of the
patients had any
postoperative complications . -
pubmed
No
patients had any
tumor recurrence during followup . -
pubmed
INTRODUCTION :
Esophageal stricture is a common complication following combined chemotherapy and radiation for advanced
oropharyngeal cancer and severely compromises
patients ' quality of life . -
pubmed
However , the near complete , or complete ,
stenosis seen in some of these
patients may also be unamenable to retrograde endoscopic dilation . -
pubmed
METHODS : Seven
patients with advanced
head and neck cancer treated with combined chemotherapy and radiation developed severe
dysphagia requiring intervention for near total , or total ,
upper esophageal stenosis . -
pubmed
RESULTS : The first
patient in the series developed a
pneumothorax during attempted passage of the guidewire in a retrograde fashion . -
pubmed
CONCLUSIONS : A retrograde endoscopic progressive balloon dilation for esophageal dilation under direct visualization provides palliation of swallowing difficulties in
patients whose
stenoses are not amenable to traditional techniques . -
pubmed
Long - term outcome of intensive chemotherapy for
adults with de novo
acute myeloid leukaemia (
AML ): the nationwide AML-92 study by the Finnish
Leukaemia Group . -
pubmed
PATIENTS AND METHODS : A total of 327 consecutive
patients with de novo
AML (
promyelocytic leukaemia excluded ) aged 16 - 65 yr were recruited into the study between September 1992 and December 2001 . -
pubmed
Median
relapse - free survival ( RFS ) for the
patients not transplanted in the first CR ( n = 195 ) was 1.7 yr ( 95 % CI : 0.81 - 2.60 ) . -
pubmed
The 5 - yr survival was 71 % , 47 % and 37 % for the non - transplanted
patients ( n = 202 ) with favourable , intermediate / normal and intermediate /
abnormal karyotypes , respectively , while only 8 % of the
patients having adverse karyotype were alive at 5 yr ( P & lt ; 0.01 ) . -
pubmed
Of the
patients with favourable , intermediate / normal or intermediate /
abnormal karyotypes , respectively , 58 % , 41 % and 31 % were expected to be alive at 10 yr . -
pubmed
CONCLUSIONS :
Idarubicin- and
cytarabine - based intensive chemotherapy regimen is very effective in de novo
AML for adult
patients up to 65 yr of age . -
pubmed
In these
patients acetabular loosening was confirmed , requiring reoperation . -
pubmed
Prenatal exposure to
cocaine has been associated with
cognitive deficits in
children and in
animal models . -
pubmed
METHODS : Twenty - six
patients with recurrent flares of non - specific
balanitis were randomly assigned to 1 group applying
pimecrolimus cream 1 % and 1 group applying placebo on the glans twice daily for 7 days . -
pubmed
A peptide - gated ion channel from the freshwater
polyp Hydra . -
pubmed
Only in the last couple of years , an ever - growing number of
human genetic diseases in the synthesis of glycoproteins have been identified . -
pubmed
Immunorestoration and augmentation of mitogen lymphocyte response in Graffi
tumor bearing
hamsters by purified
saponin mixture from
Astragalus corniculatus . -
pubmed
(
Fabaceae ) on mitogen response of the spleen cells in Graffi
tumor bearing ( GTBH ) and healthy
hamsters were reported . -
pubmed
Perinatal outcomes in severe
preeclamptic women between 24 - 33(+6 ) weeks ' gestation . -
pubmed
MATERIAL AND METHOD : A retrospective descriptive study of 99
women with severe
preeclampsia between 24 - 33(+6)-week gestation who delivered at the King Chulalongkorn Memorial Hospital from January 2002 to December 2005 was included . -
pubmed
Retraction : Impact of aortic arch stiffness on
recurrence of
stroke in
patients with
acute ischemic stroke . -
pubmed
CCV therefore represents a new avian virus of the genus Circovirus of the family Circoviridae , and is more closely related to
CoCV than BFDV.The availability of nucleotide sequence data will facilitate the development of DNA - detecting diagnostics with which the prevalence of
CCV infections can be assessed . -
pubmed
Enhanced
estrogen - induced proliferation in
obese rat endometrium . -
pubmed
OBJECTIVE : We tested the hypothesis that the proliferative
estrogen effect on the endometrium is enhanced in
obese vs lean
animals . -
pubmed
STUDY DESIGN : Using Zucker fa / fa
obese rats and lean control , we examined endometrial cell proliferation and the expression patterns of certain
estrogen - regulated proproliferative and antiproliferative genes after short - term treatment with
estradiol . -
pubmed
RESULTS : No significant morphologic / histologic difference was seen between the
obese rats and the lean
rats . -
pubmed
CONCLUSION : Enhancement of
estrogen - induced endometrial proproliferative gene expression and suppression of antiproliferative gene expression was seen in the endometrium of
obese vs lean
animals . -
pubmed
We report the case of an
infant with
BP successfully treated with oral
corticosteroids . -
pubmed
Prevention of
selenite - induced
cataractogenesis by
N - acetylcysteine in
rats . -
pubmed
PURPOSE : To evaluate the effect of
N - acetylcysteine on
selenite - induced
cataract formation in a
rat model . -
pubmed
None of the
rats in group 3 developed any
lens opacity . -
pubmed
CONCLUSIONS :
N - acetylcysteine appears to inhibit
selenite - induced
cataractogenesis in the
rat model , and this seems to be caused by the prevention of oxidative damage . -
pubmed
The prognostic significance of
bundle branch block in high - risk chronic stable
vascular disease patients : a report from the HOPE trial . -
pubmed
OBJECTIVE : The prognostic significance of left and
right bundle branch block ( LBBB and RRBB ) in
patients with chronic stable
cardiovascular ( CV ) disease is not well characterized and was evaluated in the Heart Outcomes Prevention Evaluation ( HOPE ) study cohort . -
pubmed
SETTING AND
PATIENTS : HOPE was a multicenter , international trial , which evaluated
ramipril and
vitamin E in 9,541
patients aged & gt ; or = 55 years with
CV disease or
diabetes with & gt ; or = 1 CV risk factor(s ) but without
heart failure (
HF ) or known
left ventricular systolic dysfunction . -
pubmed
RESULTS : Baseline LBBB was present in 246 ( 2.6 % )
patients and was associated with increased risk for major CV events ( HR = 1.54 ; 95 % CI , 1.18 - 2.02 ) ,
CV death ( HR 2.29 ; 95 % CI , 1.63 - 3.20 ) ,
heart failure ( HR 2.99 ; 95 % CI , 2.31 - 3.87 ) ,
sudden death ( HR 3.17 ; 95 % CI , 2.13 - 4.73 ) , and all - cause
death ( HR = 2.10 ; 95 % CI , 1.59 - 2.77 ) . -
pubmed
CONCLUSIONS : In
patients with stable chronic
CV disease , LBBB but not
RBBB is an independent predictor of
heart failure ,
sudden death ,
CV death , and all - cause
death . -
pubmed
MATERIALS AND METHODS : In this descriptive study we examined diagnostic and symptom data from a large cohort of
patients with
schizophrenia ( n = 133 ) ,
schizoaffective disorder ( n = 101 ) , or
bipolar I disorder ( n = 186 ) . -
pubmed
MPs are elevated in
diabetic patients however studies have found differences in the MP profile in relation to disease type and the presence or absence of
MPs . -
pubmed
Interestingly , elevated endothelial cell - derived MP levels are predictive in identifying a subpopulation of
diabetic patients without typical
anginal symptoms who have angiographic evidence of
coronary artery disease . -
pubmed
The
patients were followed throughout treatment , and the number of
white spot lesions was noted at debonding . -
pubmed
Plants accumulate free
L - proline (
Pro ) in response to abiotic stresses ( drought and salinity ) and presence of bacterial pathogens , including the
tumor - inducing bacterium
Agrobacterium tumefaciens . -
pubmed
Though many studies , mostly carried out in
animal models , have linked dysfunctions of single neurotransmitter systems with the pathogenesis of
HE , reports concerning neurotransmitter receptor alterations are controversial . -
pubmed
MATERIALS AND METHODS : A total of 22
neonates ( 13
girls and 9
boys ; mean gestational age , 40 weeks + /- 9 days ;
birth weight , 3203 + /- 584 g ) underwent brain MR imaging between day 1 and day 6 after birth ; 6 - noncollinear direction DTI was performed . -
pubmed
results of a randomized study in
head and neck cancer patients . -
pubmed
PATIENTS AND METHODS : 39
patients ( 8
female , 31
male ) with advanced
head and neck cancer were included in a randomised phase II study . -
pubmed
Tumour localizations : oral cavity 15
patients , oropharynx 19
patients , hypopharynx 5
patients ,
carcinoma of unknown primary 1
patient . -
pubmed
The weekly
patient analysis ( Student 's t - test ) showed a significant reduction of
dysphagia in the
selenium group ( Group 1 ) at the last week of irradiation . -
pubmed
A 93 - year - old
man presented with
jaundice and
fever . -
pubmed
PURPOSE :
Anxiety is common in
patients undergoing radiation therapy ( RT ) and in their family caregivers ( FCs ) . -
pubmed
This study aimed to identify distinct latent classes of oncology
patients and their FCs based on self - reported
anxiety symptoms from the beginning to four months after the completion of RT . -
pubmed
METHOD : Using growth mixture modeling ( GMM ) , longitudinal changes in Spielberger State Anxiety Inventory ( STAI - S ) scores among 167 oncology
outpatients with breast , prostate , lung , or
brain cancer and 85 FCs were evaluated to determine distinct
anxiety symptom profiles . -
pubmed
The results emphasise the importance of familiar
human relationships in reducing the feelings of loneliness in people experiencing
dementia . -
pubmed
We describe a 45 - year - old
woman with
peripheral embolism in whom echocardiography revealed mobile masses in the aortic arch that were characterized as
atherothrombi . -
pubmed
[ Characterization of
Vibrio parahaemolyticus obtained from environment and cases of
foodborne disease in Shenzhen , during 2006 - 2008 ] . -
pubmed
OBJECTIVE : To analyze the serological and genetic divergence in the
Vibrio parahaemolyticus from environment and cases of
foodborne disease , and to compare these two groups in terms of virulence and other biological traits . -
pubmed
Assessing global and regional left ventricular myocardial function in elderly
patients using the bidimensional
strain method . -
pubmed
POPULATION AND METHODS :
Patients without history of
cardiac disease were enrolled from the geriatric department . -
pubmed
Global longitudinal
strain was significantly lower in elderly
patients ( -20.9 + -1.9 % vs. -22.2 + -2.2 % , P<0.01 ) . -
pubmed
Such living threads have the advantage of being a particularly mild culturing medium for
mammalian cells , protecting the cells during subsequent processing steps from
dehydration and other rapid changes in the chemistry of the surrounding environment . -
pubmed
Staphylococcus aureus was the most common pathogen , causing 9
HAIs ( 15.5 % ) . -
pubmed
The combined use of surgery and radiotherapy to treat
patients with
epidural cord compression due to metastatic disease : a cost - utility analysis . -
pubmed
We enrolled 14
hypertensive patients ( seven
males , seven
females , 70 + - 6 years old ) undergoing a monotherapy of
amlodipine ,
efonidipine or
cilnidipine into this prospective , open - labeled , randomized , crossover study . -
pubmed
The nine
encephalitis patients presented with altered mental state and
seizures ,
tremor ,
weakness , or
paralysis . -
pubmed
All
patients with
encephalitis developed cerebral peduncle involvement on early magnetic resonance imaging ( MRI ) . -
pubmed
These findings may help clinicians predict the neurological outcome when evaluating
patients with
MVE . -
pubmed
METHODS :
Patients diagnosed with
AML or
ALL between the ages of 0 and 18 years who survived at least 5 years after diagnosis were included in analysis . -
pubmed
Cumulative incidences of secondary
malignancy at 30 years for
ALL patients and
AML patients were 3.9 and 4.3 % , respectively ( p = 0.10 ) . -
pubmed
Unfortunately , antiepileptic drug therapy fails to control
seizure activity in a relevant percentage of
epilepsy patients . -
pubmed
Epidemiological data as well as findings in
human epileptic tissue and in
rodent models indicate that drug resistance is a multi - factorial phenomenon with various factors contributing to therapeutic failure . -
pubmed
Further proof is obviously needed regarding the relative functional relevance of blood - brain barrier efflux for antiepileptic drug efficacy in
epilepsy patients . -
pubmed
About 500,000 new
cancer patients will develop
brain metastases in 2013 . -
pubmed
The primary treatment modality for these
patients is partial or whole brain irradiation which leads to a progressive , irreversible
cognitive impairment . -
pubmed
Today , the proportion of
diabetic patients receiving
statins is increasing due to their beneficial effect on cardiovascular mortality . -
pubmed
Tuberculosis (
TB ) and
Tuberculous meningitis (
TBM ) caused by
Mycobacterium tuberculosis (
MTB ) continue to be a major cause of morbidity and mortality . -
pubmed
Up to one - half of
patients with
olfactory dysfunction improve over time . -
pubmed
Human papillomaviruses are the causative agents of several
cancers , but only a minority of
HPV infections progress to
malignancy . -
pubmed
The association of pre - existing left
atrial fibrosis with clinical variables in
patients referred for catheter ablation of
atrial fibrillation . -
pubmed
We sought to determine pre - ablation , clinical characteristics that associate with the extent of LA
fibrosis in
patients undergoing catheter ablation for
AF . -
pubmed
METHODS AND RESULTS : Consecutive
patients presenting for catheter ablation of
AF were enrolled and underwent LGE - MRI prior to initial
AF ablation . -
pubmed
The extent of
fibrosis as a percentage of total LA myocardium was calculated in all
patients prior to ablation . -
pubmed
Of 60
patients enrolled in the cohort , 13 had & lt;5 %
fibrosis ( Group 1 ) , 15 had 5 - 7 %
fibrosis ( Group 2 ) , 17 had 8 - 13 %
fibrosis ( Group 3 ) , and 15 had 14 - 36 %
fibrosis ( Group 4 ) . -
pubmed
CONCLUSION : The extent of LA
fibrosis in
patients undergoing
AF ablation is associated with
AF type and time in continuous
AF . -
pubmed
We present a fatal case of a 59 - year - old
woman with a clinical course complicated by
venous thrombosis and
pulmonary thromboembolism that was attributed to
CCCO discovered initially at autopsy . -
pubmed
Our method is distinguished from conventional forward genetic methods because it permits ( 1 ) unbiased declaration of mappable phenotypes , including those that are incompletely penetrant ( 2 ) , automated identification of causative mutations concurrent with phenotypic screening , without the need to outcross mutant
mice to another
strain and backcross them , and ( 3 ) exclusion of genes not involved in phenotypes of interest . -
pubmed
Now one can assess blood flow and oxygenation changes resulting from functional activity and image functional response in disease models such as
stroke and
seizure , and even conduct long - term imaging of
tumor physiology , all without the confounding effects of anesthetics or
animal restraints . -
pubmed
These advances are shedding new light on
mammalian brain organization and function , and helping to elucidate loss of this organization or ' dysfunction ' in a wide array of
central nervous system disease models . -
pubmed
METHODS : One hundred and thirty - nine treatment - naive genotype 1
chronic hepatitis C patients with no history of
TD or treatment with thyroid hormones were enrolled in this study . -
pubmed
Three of the one hundred and fifteen
patients without TPOAb at baseline developed
TD at the end of treatment ( 37.5 % vs 2.6 % , P = 0.000 ) . -
pubmed
Female
patients exhibited an increased risk for developing
TD compared with male patients ( P = 0.014 ) . -
pubmed
Infection control strategies that successfully controlled an outbreak of
Mycobacterium abscessus at a
cystic fibrosis center . -
pubmed
Data on the outcomes of
M abscessus outbreaks and the efficacy of specific
infection control procedures in patients with
CF remain limited . -
pubmed
Following an
M abscessus outbreak in 2009 ,
infection control policies were intensified based on CF guidelines and surveillance data were collected and reviewed . -
pubmed
CONCLUSIONS : Direct or indirect patient - to - patient transmission of
M abscessus is a threat in the
CF population . -
pubmed
METHOD : Forty
patients of apogeotropic HSC -
BPPV colleted from March 2014 to May 2015 were divided into two groups , each group had 20 cases . -
pubmed
AIMS : ( 1 ) To study the magnetic resonance imaging ( MRI ) brain findings in
CPSs in
children aged 1 - 18 years . -
pubmed
METHODS : Hospital based prospective study in which MRI brain was done on all newly diagnosed
children with complex partial
seizures , aged 1 to 18 yrs , during the study period . -
pubmed
RESULTS : Among the 64
children who were clinically diagnosed to have
CPSs and subjected to MRI study of the brain , 40(62.5 % )
children were detected to have structural lesions , of which
neurocysticercosis (
NCC ) was noted in 17 ( 42.5 % ) ,
tuberculoma in 12 ( 30 % ) ,
hippocampal sclerosis (
HS ) in 6 ( 15 % ) ,
gliosis in 4 ( 10 % ) , and
tumor in 1 ( 2.5 % ) patient . -
pubmed
RESULTS : All
patients exhibited typical facial features and
joint dislocations . -
pubmed
CONCLUSIONS : All seven
individuals with
Larsen syndrome had a uniform clinical phenotype except for
delayed carpal ossification in two of them . -
pubmed
OBJECTIVE : To explore the genetic cause for a
child featuring
developmental delay and
mental retardation . -
pubmed
In
patients with atherosclerotic complications of
diabetes , impaired neovascularization of ischemic tissue in the myocardium and lower limb limits the ability of these tissues to compensate for poor perfusion . -
pubmed
A study on the association of
diabetic dermopathy with
nephropathy and
retinopathy in
patients with
type 2 diabetes mellitus . -
pubmed
BACKGROUND :
Diabetic dermopathy is one of the most prevalent skin complications in
diabetes patients . -
pubmed
Some studies have pointed to association of
diabetic dermopathy with
retinopathy and
nephropathy in
patients with
type 2 diabetes as
microangiopathy presentations , but no rigorous study has been conducted to confirm this association . -
pubmed
OBJECTIVES : This study investigated association of
diabetic dermopathy with
nephropathy and
retinopathy in
patients with
type 2 diabetes referring specialty clinic of Shahrekord . -
pubmed
PATIENTS AND METHODS : This descriptive , cross - sectional study was conducted on 102
type 2 diabetes patients with
dermopathy referring clinic constantly or as outpatient . -
pubmed
Dermatological and ophthalmological examinations and examination for
nephropathy were done for all
patients . -
pubmed
Prevalence of
retinopathy in
patients was 4.31 % and
nephropathy 3.33 % . -
pubmed
CONCLUSIONS : Results of this study confirm the association of
diabetic dermopathy with
retinopathy and
nephropathy in
patients with
type 2 diabetes . -
pubmed
Since
dermopathy is usually developed before
retinopathy and
nephropathy ,
dermopathy could be used as a clinical finding in early diagnosis and prevention of
retinopathy and
nephropathy in
diabetes patients . -
pubmed
OBJECTIVE : This article investigates the prevalence and attributes of
patients with
open - angle glaucoma who exhibit improvement of
visual field loss in a clinical setting . -
pubmed
DESIGN : We conducted a retrospective chart review of
patients in a clinical
glaucoma practice . -
pubmed
PARTICIPANTS : We identified 719
glaucoma patients with at least 5 SITA strategy visual field tests and a minimum continuous follow - up period of 5 years . -
pubmed
Pathological , bacteriological , and molecular characteristics of natural outbreaks of
Johne ' s disease in
goats of Fars Province , Iran . -
pubmed
The causative agent is an acid - fast bacterium ,
Mycobacterium avium paratuberculosis (
MAP ) . -
pubmed
Duchenne muscular dystrophy (
DMD ) is a
genetic neuromuscular disease that primarily affects young
males . -
pubmed
Recently a surge of new therapeutics for
DMD is offering hope to
patients . -
pubmed
Palbociclib inhibits proliferation of
human adrenocortical tumor cells . -
pubmed
First Case of
Skin and Soft Tissue Infection Caused by
Mycoplasma hominis in a Pediatric Immunocompromised Patient . -
pubmed
Patients with mild - to - moderate
hypertriglyceridemia have an increased cardiovascular risk . -
pubmed
Recently , new gene therapy approaches for
LPL - deficient patients have become available in Germany . -
pubmed
Bio - electric field enhancement : the influence on hyaluronan mediated motility receptors in
human breast carcinoma . -
pubmed
Here we show how a
human breast carcinoma cell line was maintained in media prepared with a dilute saline solution that had been exposed to a dielectrophoretic ( DEP ) electromagnetic field ( EMF ) generated by 3 amperes of direct current ( dc ) to a device housing an array of conductive rings . -
pubmed
Our studies showed a significant inhibition of growth of
human breast carcinoma MDA - MB-231 cells when they were maintained in media prepared with dc - DEP EMF force treated dilute saline while no growth inhibition occurred when the same cells were maintained in identically prepared but untreated media . -
pubmed
Also , mitotic spindle formation was inhibited in the
human breast carcinoma when they were grown in dc - DEP EMF force treated media . -
pubmed
To determine if any gene expression changes contributed to the selective growth inhibition and absent mitotic spindle formation in the
human breast carcinoma grown in the treated media , we employed microarray analysis and found that there was large - scale transcriptional reprogramming of the
tumor cells grown in the treated media with over 1,000 genes up- or down - regulated over 2 - fold , whereas the non - cancerous
MCF-10A cells showed relatively modest changes in gene expression . -
pubmed
In this study , we investigated the effects of
dioscin (
DSN ) on
human GBC and the potential mechanisms underlying these effects . -
pubmed
Prosthetic Valve Infective
Endocarditis With
Mycobacterium Fortuitum : Antibiotics Alone Can Be Curative . -
pubmed
RESULTS : Of the 69
patients , 25 had
HeFH , 25
CVD , and 19 had both . -
pubmed
CONCLUSION : In
patients with
HeFH and/or
CVD , LDLC decreased from 115 to 68 mg / dl ( 39 % ) on ALI 75 mg with mean follow - up of 49 weeks , and from 165 to 70 mg / dl ( 59 % ) on ALI - EVO over 37 weeks , p & lt ; .0001 for both . -
pubmed
Development and validation of a novel non - contact monitor of nocturnal respiration for identifying
sleep - disordered breathing in
patients with
heart failure . -
pubmed
Therefore , there is a need for simple and reliable validated methods to aid diagnosis in
patients with
HF . -
pubmed
METHODS AND RESULTS : The study included 75 adult
patients with systolic
HF and suspected
SDB who underwent simultaneous PSG and SM recordings . -
pubmed
The SM algorithm had 70 % sensitivity and 89 % specificity for identifying
patients with clinically significant
SDB ( AHI & gt;= 15 / h ) . -
pubmed
Transfer of altered behaviour and
irritable bowel syndrome with
diarrhea (
IBS - D ) through fecal microbiota transplant in
mouse model indicates need for stricter donor screening criteria . -
pubmed
In a local cohort study ,
patients had 72 % less
neck pain ( visual analogue scale rating ) and 81 % less arm
pain at 6 months when CESS was used as an isolated procedure , and 74 % less
neck pain and 83 % less arm
pain when coupled with disc replacement or fusion at an adjacent level . -
pubmed
These cytotoxic lymphocytes suppress lung
metastasis of
A549 / A2.1 lung cancer cells in
NSG mice . -
pubmed
This approach should facilitate the development of cell - based immunotherapy for
human lung cancer . -
pubmed
Combined
toxicity of
microcystin - LR and
copper on
lettuce (
Lactuca sativa L. ) . -
pubmed
The present study investigated the
toxicity effects of
microcystin - LR ( 0 , 5 , 50 , 500 , 1000 mug L-1 ) and
copper ( 0 , 50 , 500 , 1000 , 2000 mug L-1 ) , both individually and in mixture , on the germination , growth and oxidative response of
lettuce . -
pubmed
Our results suggest that the
toxicity effects of
microcystin - LR and
copper are exacerbated when they co - exist in the natural environment at low concentrations , which not only negatively affects plant growth but also poses a potential risk to
human health via the food chain . -
pubmed
MATERIALS AND METHODS : One hundred and thirty - three Mexican climacteric
women with moderate - to - severe
depression enrolled in the HOMDEP - MENOP Study ( a randomized , placebo - controlled , double - blind , double - dummy , three - arm trial , with a 6 - week follow - up study ) were evaluated . -
pubmed
Polyphenolic Composition of
Lentil Roots in Response to
Infection by
Aphanomyces euteiches . -
pubmed
Genotype ,
infection and their interaction determined the composition of
polyphenols in
lentil roots . -
pubmed
Infection increased the concentration of
kaempferol ,
apigenin , and
naringenin in the root tissues of all genotypes , but had no effect on some
polyphenols in the low -
tannin genotype
L. - pubmed
This study shows that genotypic differences exist in the composition of root
polyphenols in
lentil , and is related to the response to
infection caused by
A. - pubmed
Polyphenols , particularly the organic acid content could be useful for selection and breeding of
lentil genotypes that are resistant to
Aphanomyces root rot (
ARR ) disease . -
pubmed
BACKGROUND : Resection of pulmonary
metastases is an important treatment option for
patients with
oligometastatic melanoma . -
pubmed
Here , we report outcomes of a registry - based study of
patients who underwent lung resection for
cutaneous melanoma metastases . -
pubmed
RESULTS : Ninety - nine
patients underwent resection of cutaneous
melanoma lung
metastases . -
pubmed
CONCLUSIONS : In this unselected population - based study , 21 % of
patients were 5 - year survivors after pulmonary metastasectomy for
melanoma . -
pubmed
A 75 - year - old
man with a history of mechanical aortic valve replacement with aortic conduit for severe
aortic insufficiency underwent routine screening computed tomography evaluation revealing right coronary anastomosis
endoleak and proximal aortic root
pseudoaneurysm . -
pubmed
Short- and long - term outcomes of laparoscopic hepatectomy in elderly
patients with
hepatocellular carcinoma . -
pubmed
PURPOSE : To compare short- and long - term outcomes of laparoscopic hepatectomy ( LH ) in elderly and non - elderly
patients with
hepatocellular carcinoma (
HCC ) . -
pubmed
METHODS : Clinical and follow - up data of
patients with
HCC who underwent LH in our Institute from January 2011 to December 2016 were retrospectively analyzed . -
pubmed
RESULTS : The Charlson comorbidity index and American Society of Anesthesiologists ( ASA ) score of
patients in the elderly group were higher than those of patients in the nonelderly group , and the rates of
hepatitis virus infection and
cirrhosis in the elderly group were lower than those in the non - elderly group . -
pubmed
Old age is not a contraindication for LH in
patients with
HCC . -
pubmed
METHODS : This institutional review board - approved prospective double - blinded trial involved 111
patients with
adolescent idiopathic scoliosis who were randomized to receive either a placebo or
TXA ( 50 - mg / kg loading dose and 10 - mg / kg / h infusion ) . -
pubmed
Power analysis indicated that 50
patients per group would provide power to detect a & gt;20 % difference in
blood loss . -
pubmed
CONCLUSIONS : Use of
TXA in
patients undergoing surgery for adolescent
idiopathic scoliosis significantly reduced
blood loss , by 27 % , compared with that in the placebo group . -
pubmed
Patients with greater intraoperative
blood loss spent a longer time in the hospital . -
pubmed
METHODS : 40
patients between 3 to 18 years of age , with clinical diagnosis of acute
rheumatic fever or new activity in established
rheumatic heart disease were included . -
pubmed
Effects of
omega-6 / 3 and omega-9/6 nutraceuticals on
pain and fertility in
peritoneal endometriosis in
rats . -
pubmed
MATERIALS AND METHODS : Study analyses the 244 ECG indices in 111
patients ( 79
males and 32
females , age 53 + -17 years ) with
RBBB tachycardias , who underwent electrophysiological studies . -
pubmed
First step includes retrospective analysis of QRS characteristics in 20
patients with
ventricular tachycardias (
VT ) , 24 pts with aberrant
supraventricular tachycardias (
SVT+
RBBB ) and 14 pts with antidromic
SVTs (
WPW ) . -
pubmed
The prognostic accuracy of the algorithms was subsequently evaluated on a prospective group of
patients with
RBBB tachycardias ( n=53 ) . -
pubmed
The ITP working group of the Spanish Society of Paediatric Haematology and Oncology has updated its guidelines for diagnosis and treatment of primary
immune thrombocytopenia in
children , based on current guidelines , bibliographic review , clinical assays , and member consensus . -
pubmed
Nephrotoxicity of
amikacin in noncritically ill
patients : . -
pubmed
AIMS : Several studies have reported that
critically ill patients who require
amikacin for the treatment of severe
infection require therapeutic drug monitoring ( TDM ) to prevent
acute kidney injury . -
pubmed
Therefore , the aim of this study was to investigate the
nephrotoxicity and tolerability of
amikacin in noncritically ill
patients . -
pubmed
However , an increasing trend of
AKI risk was observed in
patients with low baseline estimated
glomerular filtration rate . -
pubmed
CONCLUSION : In noncritically ill
patients , the incidence of
amikacin - induced
nephrotoxicity was lower than that reported in previous studies . -
pubmed
Methods : Eighteen
patients with
N2O abuse or
vitamin B12 deficiency were recruited . -
pubmed
Conclusion : Compared to
vitamin B12 deficiency ,
N2O abuse
patients showed prominent motor superexcitability changes and less prominent sensory superexcitability changes , hinting a unique
pathological process different from that of
vitamin B12 deficiency . -
pubmed
RESULTS : In 2891 men and 4002
women aged 50 - 79 years , 1099
non - vertebral osteoporotic fractures - including 393
hip fractures - were sustained during the median 15 years follow - up . -
pubmed
Rapid Proteome Changes in Plasma and Cerebrospinal Fluid Following
Bacterial Infection in Preterm Newborn
Pigs . -
pubmed
Feeding
bovine colostrum reduced the
sepsis - related changes in clinical indices and plasma proteins . -
pubmed
Conclusion :
Systemic infection with
SE induces
inflammation with rapid proteome changes in the plasma and CSF in preterm newborn
pigs . -
pubmed
The observed early markers of
sepsis and neuroinflammation in preterm
pigs may serve as novel biomarkers for
sepsis in
preterm infants . -
pubmed
Methods : In vivo , different concentrations of
aloin were intraperitoneally injected 1 h before the establishment of the
HIR model in male
mice . -
pubmed
In vitro ,
aloin ( AL ,
C21H22O9 ) or lipopolysaccharide ( LPS ) was added to a culture of
mouse primary hepatocytes before it underwent
hypoxia / reoxygenation ( H / R ) , and the apoptosis in the
mouse primary hepatocytes was analyzed . -
pubmed
Values of intravoxel incoherent motion diffusion weighted imaging and dynamic contrast - enhanced MRI in evaluating the activity of
sacroiliitis in
ankylosing spondylitis of
rat model . -
pubmed
OBJECTIVE : To prospectively evaluate the ability of IVIM - DWI and DCE - MRI in detecting early activity of
sacroiliitis in
rat model of
ankylosing spondylitis by comparing with pathological results . -
pubmed
Chronic Oral
Palmitoylethanolamide Administration Rescues
Cognitive Deficit and Reduces
Neuroinflammation , Oxidative Stress , and
Glutamate Levels in A Transgenic
Murine Model of
Alzheimer ' s Disease . -
pubmed
In this study , we evaluated the neuroprotective and antioxidant effects of chronic ( three months ) um -
PEA administration in an
animal model of
AD ( 3xTg -
AD mice ) . -
pubmed
The chronic treatment with
um - PEA ( 100 mg / kg / day for three months ) rescued
cognitive deficit , restrained
neuroinflammation and oxidative stress , and reduced the increase in hippocampal
glutamate levels observed in 3xTg -
AD mice . -
pubmed
Overall , these data reinforce the concept that
um - PEA exerts beneficial effects in 3xTg -
AD mice . -
pubmed
Icariin is a main component of the Chinese medicinal plant
Epimedium brevicornu Maxim , exhibits potent activity against
inflammatory diseases . -
pubmed
Herein , we investigated the effects of
icariin on primary cultured fetal
rat hippocampal neurons and OVALPS - OVA induced
asthma rat model . -
pubmed
A novel actinomycete , designated
strain NEAU - C151 T , was isolated from soil collected from Mount Song and characterized using a polyphasic approach . -
pubmed
The type
strain is
NEAU - C151 T (= CGMCC 4.7498T = DSM 107808 T ) . -
pubmed
PURPOSE : To evaluate the outcome of robot - assisted residual mass resection ( RA - RMR ) in
nonseminomatous germ cell tumor ( NSGCT )
patients with residual
tumor following chemotherapy . -
pubmed
Patients were considered for RA - RMR in case of a residual
tumor between 10 and 50 mm at cross - sectional computed tomography ( CT ) imaging located ventrally or laterally from the aorta or vena cava , with normalized
tumor markers following completion of chemotherapy , and no history of retroperitoneal surgery . -
pubmed
Histopathology showed
teratoma ,
necrosis and viable
cancer in 29 ( 64.4 % ) , 14 ( 31.1 % ) , and two
patients ( 4.4 % ) , respectively . -
pubmed
This
neurological disorder has been previously reported in bone marrow transplant
recipients but is uncommon after kidney transplantation . -
pubmed
CASE PRESENTATION : In this report , we present a case of a 47 - year - old male
patient 12 years after his second kidney transplantation who developed
GBS due to
papillary renal cell carcinoma . -
pubmed
CONCLUSIONS : In kidney transplant
recipients , paraneoplastic aetiology should be considered in the differential diagnosis of
GBS . -
pubmed
Cardiac manifestations and effects of enzyme replacement therapy for over 10 years in
adults with the attenuated form of
mucopolysaccharidosis type I. -
pubmed
There have been only a few reports on the effect of long - term enzyme replacement therapy ( ERT ) for adult
patients with the attenuated form of
MPS I (
Scheie syndrome ) and
cardiac involvement . -
pubmed
Methods : We retrospectively reviewed four adult
patients of
Scheie syndrome for which ERT was performed in our hospital . -
pubmed
We investigated the findings of electrocardiography and echocardiography for the four
patients performed before and 10 years after the initiation of ERT to evaluate the efficacy for ERT in
Scheie syndrome . -
pubmed
One
patient had gradual progressive
aortic valve stenosis and
mitral valve stenosis during the course of ERT , and double valve replacement was finally performed . -
pubmed
The
patient who had started ERT at the youngest age did not develop significant
cardiovascular disease . -
pubmed
Regarding clinical courses with ERT for a period of 10 years , all four
patients survived and they showed relatively stable cardiac conditions although two
patients developed
sick sinus syndrome after the valvular surgery . -
pubmed
Conclusions :
Valvular disease in
patients with
Scheie syndrome occur at a young age . -
pubmed
OBJECTIVES : To analyse the diagnostic performance of
eosinopenia , alone or combined with polymorphonuclear neutrophils ( PMN ) and/or lymphocytes , as a marker of active
COVID-19 in
patients hospitalized for suspicion of
SARS - CoV-2 infection . -
pubmed
RESULTS : One - hundred and twenty - one patient were included : 57
patients were diagnosed with
COVID-19 , 64
patients were not . -
pubmed
CONCLUSION :
Eosinopenia - < 10 / muL - and eosinophil / PMN ratio are useful , low - cost , reproducible tools to help diagnose
COVID-19 , during an epidemic period , in a population of hospitalized
patients admitted for suspicion of
COVID-19 . -
pubmed
Needle electromyography of craniobulbar muscles in
patients with
amyotrophic lateral sclerosis : Direct comparison between genioglossus and masseter muscles . -
pubmed
Three main variants are described in
males :
adrenomyeloneuropathy (
AMN ) , a cerebral form (
cALD or
cAMN ) and
Addison ' s disease only (
AD ) , while for
females no classification is used . -
pubmed
To evaluate
pain and the functional state of afferent fibers , a series of tests was carried out in male and female
patients . -
pubmed
METHODS :
Chronic pain occurrence and sensory phenotype profile were assessed in 30
patients ( 20 male : 10
AMN , 1
cAMN , 1
cALD , 8
AD ; and 10 female ) . -
pubmed
Male
AMN /
cAMN /
cALD patients showed the worst impairment . -
pubmed
Cardiovascular complications in COVID-19
patients with or without
diabetes mellitus . -
pubmed
Multivariate logistic regression was used to estimate the adjusted odds ratio for the study outcomes in
DM patients , compared to those without
DM , stratified by age , sex and glycaemic control . -
pubmed
The unadjusted rates were higher in
DM patients compared to non - diabetics for the composite cardiovascular end - point ( 73.2 % vs. 40.6 % p < .0001 ) , acute
myocarditis ( 36.6 % vs. 15.5 % p = .004 ) ,
acute heart failure ( 25.3 % vs. 5.6 % p = .001 ) , acute
myocardial infarction ( 9.9 % vs. 1.4 % p = .03 ) and new - onset
atrial fibrillation ( 12.7 % vs. 1.4 % p = .009 ) . -
pubmed
After controlling for relevant confounding variables ,
diabetic patients had higher odds of composite cardiovascular end - point , acute
heart failure and new - onset
atrial fibrillation . -
pubmed
A 30 - year - old male
patient presented with history of
haemoptysis associated with
cyanosis and
clubbing . -
pubmed
This low molecular weight protein is found in the urine of some
patients with
renal tubular disorders , but some workers have emphasized its importance as a causal agent in
hypokalaemia of
acute myeloid leukaemia . -
pubmed
The
patients selected for treatment have presented
chondrosarcoma ( ten ) , so - called
benign giant - cell tumour of bone , usually recurrent ( nine ) ,
angiomatous osteolysis ( two ) , seemingly single thyroid or renal
metastasis ( two ) , and ununited pathological
fracture after irradiation of a
tumour ( one ) . -
pubmed
Tryptophan metabolism and
recurrence rates of
patients with
breast cancer after mastectomy . -
pubmed
Women with early
breast cancer were given a loading dose of
L - tryptophan after mastectomy and a comparison made between their excretion of metabolites of the
kynurenine pathway and the rate of
recurrence of the disease . -
pubmed
Fecapentaene excretion and fecal
mutagenicity in relation to nutrient intake and fecal parameters in
humans on omnivorous and vegetarian diets . -
pubmed
Fecapentaenes are strong fecal mutagenic compounds presumably occurring in the majority of Western
human individuals , and are possibly essential initiators of colon
carcinogenesis . -
pubmed
Since
vegetarians at low risk for
colorectal cancer excrete higher concentrations of
fecapentaenes , it could be hypothesized that relatively increased
fecapentaene excretion in combination with antimutagenic compounds in feces represents
colon cancer prevention . -
pubmed
Pretreatment
patients showed significantly higher ratio of complete remission than relapsed
patients , and mean value of IC50 for
adriamycin in initial presentation was higher than at
relapse . -
pubmed
[ Renal protection in
diabetic patients with
ACE inhibitors ] . -
pubmed
[ Clinico - immunomorphological characteristics of the mucosa of the distal segments of the large intestine in
children with
gastroduodenitis ] . -
pubmed
The clinical , x - ray , endoscopic and morphological studies performed in 156
children afflicted with
gastroduodenitis have shown that concomitant lesions of the colon are of paramount importance in the genesis of this illness . -
pubmed
In vivo administration of
bromodeoxyuridine and flow cytometry for cell kinetic studies in
human malignancies . -
pubmed
[ Results of drug sensitivity test of
UFT ,
doxorubicin and
cisplatin using
human urogenital cancers transplanted subcutaneously into
nude mice ] . -
pubmed
Experimental chemotherapy with
UFT ,
doxorubicin and
cisplatin was performed against
human urogenital cancers transplanted subcutaneously into
nude mice . -
pubmed
The
tumor take was confirmed in 33 cell lines of
human neoplasms which consisted of 10
renal cell carcinomas , 5
renal pelvic carcinomas , 3
ureteral carcinomas , 8
carcinomas of the urinary bladder , 3
prostatic carcinomas and 4
testicular tumors . -
pubmed
Amongst adults exposed to the
hepatitis B virus (
HBV ) , the
infection pursues a fulminant course more frequently in females , while conversely a chronic carrier state is more frequent in males . -
pubmed
That this was not a nonspecific effect of
fulminant hepatitis was confirmed by the significantly higher levels in this group than in age - matched females with
fulminant hepatitis unrelated to
HBV ( P less than .05 ) . -
pubmed
An
intimal sarcoma of the abdominal aorta in a 63 - year - old
woman is reported . -
pubmed
Noradrenaline acutely ( 30 min ) increased BAT mitochondrial
GDP binding of lean and
obese Zucker
rats , without any change in uncoupling - protein concentrations . -
pubmed
[
Pyridoxal and
pyridoxamine phosphate levels in the plasma and bone marrow of
children with
acute leukemia ] . -
pubmed
Twenty - six
patients with
idiopathic Raynaud ' s phenomenon participated in a double - blind , crossover clinical trial comparing the clinical effect of
nifedipine with that of placebo . -
pubmed
From 1977 to 1985 , 22
patients less than 4 years of age ( mean age 18.2 months ) underwent direct aortic reimplantation of the
anomalous left coronary artery . -
pubmed
Moderate to severe preoperative
mitral incompetence lessened in all
patients but one , without mitral valve repair . -
pubmed
Infants with severely
impaired left ventricular function and persistent
congestive heart failure should probably undergo operation as soon as the diagnosis has been made . -
pubmed
Since 1980 , 112
patients presenting with
tumours of the eyelid were treated by cryotherapy at the First University Department of Ophthalmology in Vienna . -
pubmed
Tumour recurrence existed in 29 of these
patients who had previously undergone surgical treatment or radiotherapy . -
pubmed
Within a follow - up period of 5 years , 9 % of the
patients with
basal cell epithelioma and
spindle cell epithelioma experienced recidivation . -
pubmed
All 6 infected monkeys developed primary and satellite cutaneous
leishmanial lesions which were measured for up to 30 weeks in 3 of the
monkeys and up to 52 weeks in the other 3
monkeys . -
pubmed
Two
owl monkeys which had recovered from
cutaneous leishmaniasis demonstrated acquired resistance when challenged with an intradermal inoculation of
L. - pubmed
b. panamensis were similar in many respects to those observed in
humans with localized
cutaneous leishmaniasis . -
pubmed
Oncogenic transformation of
hamster embryo cells after exposure to inactivated
herpes simplex virus type 1 . -
pubmed
The in vitro transformation of hamster embryo fibroblasts by
herpes simplex virus type 1 (
HSV-1 ) after exposure of the virus to UV irradiation is described . -
pubmed
Cell transformation was induced by 2 out of 12
strains of
HSV-1 that were tested for transforming potential . -
pubmed
Cells transformed by the KOS
strain of
HSV-1 were not oncogenic when injected into newborn
Syrian hamsters . -
pubmed
However , cells transformed by
HSV-1 strain 14 - 012 induced
tumors in 47 % of the newborn
hamsters injected . -
pubmed
Immunopathology and
microvascular lesions in
human sympathetic ganglia . -
pubmed
Lumbar sympathetic ganglia surgically removed from adult
patients affected by obstructive
peripheral arteriopathies are investigated with traditional histology and fluorescent antibody technique . -
pubmed
Patients with disorders of hemostasis who undergo surgical procedures are in danger of
hemorrhage . -
pubmed
In three
patients with
coagulopathy - one with mild classical
hemophilia , one with
Christmas disease , and one with
warfarin toxicity - the abnormality was missed by routine preoperative history but promptly detected by the routine preoperative use of the activated coagulation time ( act ) . -
pubmed
Effect of
dopamine on
pentagastrin - stimulated gastric antral motility in
dogs with
gastric fistula . -
pubmed
The purpose of the present study was to evaluate the effect of
dopamine on gastric antral motility in conscious
dogs with
gastric fistula by using miniature
strain - gauge transducers . -
pubmed
A comparative study of the diagnosis value of drug - induced sleep EEGs and sleep EEGs following
sleep deprivation in
patients with complex partial
seizures . -
pubmed
On the following day a sleep EEG of the same
patient was recorded after
sleep deprivation of 24 - -26 h. If only
patients whose wake EEGs were free from
epileptic activity are considered , the rate of provocation was 58 % . -
pubmed
For practical purposes it is recommended that for those
patients whose wake EEGs are free from
epileptic activity , a sleep EEG -- possibly drug - induced -- should be recorded . -
pubmed
Central and peripheral cardiovascular actions of
urapidil in normotensive and Goldblatt
hypertensive animals . -
pubmed
The central effect of
urapidil on mean arterial blood pressure , heart rate , and reflex
tachycardia was studied in anesthetized normotensive and Goldblatt
hypertensive dogs and anesthetized
cats . -
pubmed
Complications were few ;
drowsiness occurred in 9 % ,
dizziness was troublesome in one
patient , but there was no
nausea or
vomiting and no one became unconscious . -
pubmed
Peak plasma levels of 177 and 270 micrograms / ml were reached 1 h after the initial injection and therapeutic levels persisted for at least 12 h. This initial study indicated that a suggested dose regime in snakes , derived by extrapolation from
mammalian dosages , of 100 - 125 mg / kg daily was insufficient to produce plasma levels of sufficient magnitude and duration to effectively treat
Pseudomonas infections in snakes . -
pubmed
The electrophysiologic effects of intravenous
verapamil and
propranolol were compared alone and in combination in 14
patients ( aged 21 to 69 years ) with paroxysmal
supraventricular tachycardia (
SVT ) . -
pubmed
Ten
patients had
atrioventricular ( AV ) reentry utilizing a manifest ( 7
patients ) or concealed ( 3
patients ) accessory pathway . -
pubmed
Verapamil or
propranolol prevented
SVT induction in 7
patients ( 50 % ) . -
pubmed
However , only the drug combination prevented reinduction of sustained
SVT in 6
patients . -
pubmed
These 6
patients were treated chronically with
verapamil and
propranolol , with no recurrence of
SVT in any
patient after 2 to 26 months . -
pubmed
Acetaminophen metabolism and clearance after a single 1 gm oral dose of the drug was investigated in 12 healthy
men , six of whom were cigarette smokers , and in six
men who were receiving anticonvulsant drugs for
epilepsy . -
pubmed
In contrast ,
sulfinpyrazone pretreatment increased ClAP by 23 % ( from 5.70 + /- 0.21 to 7.00 + /- 0.39 ml / min / kg ) and ClAP was 46 % greater in the
epileptic subjects who received anticonvulsant drugs than in the control group ( 8.32 + /- 0.45 and 5.70 + /- 0.21 ml / ml / kg ) . -
pubmed
In order to elucidate the still controversial question whether
iron foreign bodies located in the orbit can produce
siderosis bulbi , the authors studied the concentration of
iron in the aqueous of
rabbits in which the metal was placed outside the eyeball , close to the exposed sclera . -
pubmed
Relation of antibody - coated urine bacteria to the site(s ) of
infection in experimental
dogs . -
pubmed
It was concluded that the antibody - coated bacteria test does not provide accurate information to support the diagnosis of
pyelonephritis in the
dog . -
pubmed
Antibodies to antigens presumably associated with Hodgkin 's (
HD ) and antigens associated with
HD and
Non - Hodgkin lymphomas (
NHL ) have been isolated by an immunosorbent procedure using serum of an untreated
patient with
HD and his affected splenic tissue immobilized in polyacrylamide gel . -
pubmed
The inflammatory cell composition of pleural or ascitic effusion fluids from 13
patients with
malignant disease and 8
patients with benign disease was analyzed . -
pubmed
The
smallpox story :
man finally defeats an old adversary . -
pubmed
For this reason immediate surgical decompression ( including the meatal foramen ) was performed on 14
patients with 90 % or more degeneration within three weeks of
palsy onset . -
pubmed
Overloading of the highest nervous activity induced no
hypertension in these
animals , though the self - stimulation frequency increased . -
pubmed
Renal artery constriction resulted in a fast and large
increase in blood pressure in comparison with that of control
rats . -
pubmed
We think that the possibility of this anatomic arrangement should always be considered in
patients with isolated
aortic coarctation whose clinical condition seems impaired rather than improved after an apparently successful coarctectomy . -
pubmed
RESULTS : At admission , 12
patients were
comatose ( Glasgow Coma Scale & lt ; 10 ) , 7 had generalized
convulsions . -
pubmed
Four
patients died during the study , 3 from
multiple organ failure . -
pubmed
The
chromosome aberration frequency in
murine somatic cells was studied . -
pubmed
In 4 years we performed primary reconstruction of
cloacal anomalies in 4
children , 3 of whom had
hydrocolpos and 1
vaginal agenesis . -
pubmed
Distal
vaginal occlusion related to
ischemia occurred in 2
patients and in both the vagina was successfully reconstructed at a second stage procedure . -
pubmed
OBJECTIVES : This study attempted to determine the incidence , prognosis and predictability of postoperative
left ventricular dysfunction in
patients undergoing correction of
mitral regurgitation . -
pubmed
BACKGROUND : Left ventricular function in
patients with
mitral regurgitation is altered by loading conditions and is difficult to assess . -
pubmed
METHODS : In 266
patients undergoing correction of
mitral regurgitation between 1980 and 1989 , left ventricular function was echocardiographically assessed preoperatively ( within 6 months ) and postoperatively ( within 1 year ) . -
pubmed
Postoperative
left ventricular dysfunction ( ejection fraction & lt ; 50 % ) was frequent ( 41 % of
patients ) and carried a poor prognosis ( at 8 years survival , 38 % + /- 9 % vs. 69 % + /- 8 % , p & lt ; 0.0001 ) . -
pubmed
Gliomatosis peritonei (
GP ) is the implantation of glial tissue on the peritoneal surface in
patients with solid
ovarian teratoma . -
pubmed
Early parenteral nutrition in
patients unconscious because of acute
drug poisoning . -
pubmed
The author studied the clinical and laboratory effects of early parenteral nutrition ( EPN ) in
patients who were
comatose as a result of acute
drug poisoning . -
pubmed
These results suggest that although the pharmacokinetic profiles of
losartan and
E-3174 do not change during repeated administration , the blood pressure lowering effect in
hypertensive patients is greater after multiple doses than after a single dose . -
pubmed
To our knowledge concomitant
avulsion fractures in this condition have not been reported thus far in pediatric
patients . -
pubmed
Vagal activation in novelty - induced
tachycardia during the light phase in the
rat . -
pubmed
The
CD4 + T - cell clones developed against
SLA class II - negative PAECs recognized
strain - specific
porcine xenoantigens indirectly . -
pubmed
Thresholds were measured at implant , predischarge , and at a mean follow - up of 50 days in 46
patients with a uniform testing protocol and
shock polarity . -
pubmed
CLINICAL CASE : We present the case of a
man with cutaneous lesions compatible with the diagnosis of
neurocutaneous melanosis since birth , with benign self - limiting
epilepsy in early childhood . -
pubmed
MR should be done periodically in
patients with
cutaneous lesions suggestive of this condition . -
pubmed
In conclusion , inhaled
NO , given with a high FiO2 , in the presence of this established endotoxinic
lung injury did not reverse the markers of PMN activation studied nor
lung edema formation in this
rat model . -
pubmed
Accordingly ,
human cancers and some premalignant
lesions contain multiple
genetic abnormalities not present in the
normal tissues from which the
neoplasms arose . -
pubmed
Varicocele repair improves semen parameters in azoospermic
men with
spermatogenic failure . -
pubmed
PURPOSE : We analyzed the efficacy of
varicocele repair in improving semen parameters in azoospermic
men with
spermatogenic failure . -
pubmed
MATERIALS AND METHODS : After routine clinical evaluation with confirmatory pellet analysis testicular biopsy and
varicocele repair were simultaneously performed in 28 azoospermic
men with a primary diagnosis of unilateral or bilateral
varicocele and
spermatogenic failure . -
pubmed
Only 9
men with severe
hypospermatogenesis and 5 with maturation arrest spermatid stage had improvement in sperm density . -
pubmed
The reduction in local
recurrences seen in
patients with
head and neck cancer following radiotherapy led to coining of the term " subclinical disease " to describe the presumed presence of small , clinically undetectable , nests of
tumor cells which remain even after the most aggressive of surgeries . -
pubmed
Peculiarities of modifications of errors made by
human subjects in identification of masked visual images within the "
fatigue -- negative emotions " range were investigated . -
pubmed
Detection of
sialic acids and
gangliosides with special reference to
9 - O - acetylated species in
basaliomas and normal
human skin . -
pubmed
UNLABELLED : In addition to
patients with
coronary artery disease , high - risk
patients with severe
congestive heart failure can benefit from rehabilitation . -
pubmed
This review explores these beneficial outcomes through an assessment of therapeutic approaches , with special emphasis on the unique clinical characteristics of
patients with
congestive heart failure . -
pubmed
OVERALL ARTICLE OBJECTIVE : To describe the benefits and the evolving role of cardiac rehabilitation for
patients with
congestive heart failure . -
pubmed
A case is reported of a young
woman who , within a 2 - year period , was diagnosed with an
osteoblastoma at the apex of a maxillary molar and with a plexiform
unicystic ameloblastoma in the posterior mandible . -
pubmed
Rational therapy of
chronic venous insufficiency -- chances and limits of the therapeutic use of
horse -
chestnut seeds extract . -
pubmed
BACKGROUND AND METHODS : We report two clinical studies , one already published , performed in
patients with early and advanced
chronic venous insufficiency (
CVI ) . -
pubmed
Nylon membranes with two
spots of UV - immobilized primer pairs -- one for
BVDV and one for
BHV -- were used in amplification with both corresponding templates , with each template singly and with no template . -
pubmed
Effects of
L - arginine on blood pressure and metabolic changes in
fructose -
hypertensive rats . -
pubmed
Our data also suggest a strong relationship between
hyperinsulinemia and
hypertension in this
hypertensive rat model . -
pubmed
Central nervous system relapse in
adults with
acute lymphoblastic leukemia . -
pubmed
BACKGROUND :
Recurrence of
acute lymphoblastic leukemia (
ALL ) in the central nervous system ( CNS ) in
adults is considered a poor prognostic feature . -
pubmed
The objective of this study was to analyze the experience with CNS recurrence in adult
patients with
ALL . -
pubmed
METHODS : Between December 1982 and April 2000 , the records of 527 consecutive , newly diagnosed
patients with
ALL who were treated at the M. D. Anderson Cancer Center were reviewed . -
pubmed
All
patients had received CNS prophylaxis tailored to the risk of CNS
recurrence with systemic chemotherapy with or without intrathecal ( IT ) chemotherapy ; none received cranial radiotherapy for prophylaxis . -
pubmed
Three groups were identified : 1 )
patients with an isolated CNS
recurrence ( n = 17
patients ) , 2 )
patients with CNS
recurrences after bone marrow ( BM )
recurrence ( n = 8
patients ) , and 3 )
patients with simultaneous CNS and BM
recurrences ( n = 7
patients ) . -
pubmed
The median survival from CNS
recurrence was 6 months ; 28 % of
patients were alive at 1 year , and 6 % of
patients were alive at 4 years . -
pubmed
CONCLUSIONS :
Adults with
ALL and CNS
recurrences have a poor prognosis despite effective IT chemotherapy . -
pubmed
Effective CNS prophylaxis remains the single best approach for treating
patients with
CNS leukemia . -
pubmed
Their anti - fungal activity against
Pyricularia oryzae and
cytotoxic activity on
K562 and
HCT-15 cell lines were evaluated in vitro . -
pubmed
LDL receptor - deficient male
mice were randomly divided into 4 groups ( n = 11 each ) . -
pubmed
The
diabetic and the nondiabetic
mice were sacrificed after 3 and 5 weeks , respectively . -
pubmed
The
atherosclerotic plaque area was significantly smaller in the
omapatrilat - treated
mice , both
diabetic and nondiabetic , as compared to nontreated controls . -
pubmed
In the
diabetic animals , the plaque area was 8887 + /- 5386 microm2 and 23220 + /- 10400 microm2 , respectively for treated and nontreated
mice ( P = .001 ) . -
pubmed
Plasma lipids were increased by
omapatrilat : Mean plasma
cholesterol in treated
mice ,
diabetic and nondiabetic combined , was 39.31 + /- 6.00 mmol / L , versus 33.12 + /- 7.64 mmol / L in the nontreated
animals ( P = .008 ) . -
pubmed
We performed a pilot study of breath VOCs , a potential new marker of disease in
women with
breast cancer . -
pubmed
This was a combined case - control and cross - sectional study of
women with
abnormal mammograms scheduled for a breast biopsy . -
pubmed
[ Treatment of
schizophrenia in
children ] . -
pubmed
[
Food poisoning caused by
Salmonella enteriditis & amp ;
Escherichia coli 055 B5 ] . -
pubmed
Antimicrobial activity of
penicillin V and
phenethicillin with special reference to organisms isolated from 17
patients with subacute
bacterial endocarditis . -
pubmed
Development of mast cell reaction during chemical skin
carcinogenesis of
mouse . -
pubmed
Epidemiological and bacteriological features of
infections associated with an organism related to
Salmonella paratyphi B. -
pubmed
Nicotine is not clastogenic at doses of 1 or 2 mg / kg
body weight given orally to
male mice . -
pubmed
These data contradict the only published in vivo study of
nicotine in which 1.1mg / kg bw was called positive for the induction of
chromosomal aberrations in
mouse bone marrow cells at all sampling intervals , even as early as 6h after treatment . -
pubmed
Evidence of subtle
auditory deficit in a group of
patients recovered from
bacterial meningitis . -
pubmed
OBJECTIVES :
Sensorineural hearing loss of greater than 30 dB
hearing loss occurs in up to 30 % of
patients after acute
bacterial meningitis . -
pubmed
This study investigated whether postbacterial
meningitic patients with no apparent clinical
sensorineural hearing loss had any evidence of more subtle subclinical
cochlear deficit . -
pubmed
PATIENTS : Fifty - eight controls and 20 postbacterial
meningitic patients aged between 18 and 38 years were screened by a questionnaire and tympanometry to exclude
hearing loss attributable to other causes . -
pubmed
RESULTS : Mean thresholds over the range of standard pure - tone audiometry ( analyzed independently ) for the postbacterial
meningitic patients were significantly elevated at most frequencies ( p & lt ; 0.05 - p & lt ; 0.001 ) between 4 and 7 dB in both ears above control group values . -
pubmed
CONCLUSIONS : Postbacterial
meningitic patients with hearing below the 90th percentile range had a slight but significant subclinical threshold elevation over the standard pure - tone audiometry . -
pubmed
Two
patients with
dural sinus thrombosis and rapidly deteriorating levels of consciousness underwent unsuccessful attempts at mechanical thrombolysis via the usual transfemoral route . -
pubmed
Individuals with
schizophrenia are know to demonstrate cognitive and behavioral difficulties , particularly alterations in executive functions , including working memory . -
pubmed
It is unclear whether these deficits reflect trait - related vulnerability to
schizophrenia indicators and can be assessed by studying nonpsychotic relatives of
patients with
schizophrenia . -
pubmed
In this study , we used an oculomotor delayed response ( ODR ) paradigm to examine spatial working memory in 37 " high - risk " child and adolescent offspring and siblings ( age range=6 - 25 years ) of
patients with
schizophrenia or
schizoaffective disorder . -
pubmed
The influence of anatomical variations in
patients with left dominant circulation on
coronary arteriosclerosis is not clear . -
pubmed
METHODS : We examined 139
patients with
polyp using colonoscopy and mucosal staining , and observed the pit patterns ( proposed by Kudo ) with magnifying endoscope and stereomicroscope to identify the relations between the pit patterns and the pathologic diagnosis . -
pubmed
RESULTS :
Polyps were identified in 124
patients and advanced
cancers in 9 . -
pubmed
It is essential therefore to be able to estimate an individual
patient 's risk of harboring clinically silent micrometastatic
disease using established prognostic factors . -
pubmed
It is standard practice to administer systemic therapy to all
patients with lymph node - positive
disease . -
pubmed
A new guidance device facilitates percutaneous puncture of the foramen ovale in
human cadavers . -
pubmed
CONCLUSION : The employment of a guidance device facilitated percutaneous transforaminal puncture and resulted in a significantly decreased number of puncture attempts as compared to free - hand techniques in
human cadavers . -
pubmed
Even though
central nervous system disturbances occurred more frequently among
efavirenz - treated
patients and nonclinically significant
transaminitis occurred more frequently among
nevirapine - treated patients , these adverse events were not statistically significant or mutually exclusive . -
pubmed
We designed this study to examine whether postanesthesia
learning impairment is persistent in young
rats . -
pubmed
Hence , in adult
rats , previous general anesthesia is not associated with
impaired learning 2 wk later . -
pubmed
One
patient complained of
pain during removal of a spacer . -
pubmed
In the presented case , only the
patient 's clinical course and duplex sonography , which showed bilateral cervical arterial dissections , led to the diagnosis of
aortic dissection . -
pubmed
This case emphasizes that early ultrasound examination is crucial in
patients with suspected
cerebral ischemia . -
pubmed
In this report we describe a 16 - month - old
boy who presented with
aplastic anaemia preceding a non - A , non - B ,
non - C fulminant liver failure . -
pubmed
These
patients also need to be evaluated extensively in order to exclude a primary
immunodeficiency . -
pubmed
Anxiety - like behavior of young
rats after 2 - week
zinc deprivation . -
pubmed
In the plus - maze test , the time spent in the open arms was also decreased in
zinc - deficient
rats , suggesting that
anxiety - like behavior is increased in
zinc deficiency . -
pubmed
Nine
patients with
carotid body tumors were identified , three of them with complicated diagnosis . -
pubmed
MATERIAL AND METHODS : Severe
CAP in
patients ( n = 103 , aged 18 - 60 years , male 89 % ) were randomly subdivided into the 4 comparable groups . -
pubmed
[ Thermal therapy for
patients with chronic
heart failure ] . -
pubmed
Crude extracts of
Euchresta formosana radix inhibit invasion and migration of
human hepatocellular carcinoma cells . -
pubmed
Frontal lobe dysfunction in
children with
temporal lobe epilepsy . -
pubmed
There is evidence that
adults with
temporal lobe epilepsy present
executive impairments . -
pubmed
We aimed to : 1 ) investigate the presence and severity of
executive dysfunctions in
children with
temporal lobe epilepsy , and 2 ) determine the implications of clinical variables ( including etiology ) in the occurrence and severity of
executive dysfunction , using eight paradigms . -
pubmed
Thirty - one
children with
temporal lobe epilepsy were evaluated and compared with 21 age - matched controls . -
pubmed
Patients with
temporal lobe epilepsy had significantly worse performance than controls . -
pubmed
Intragroup analysis indicated that
patients with symptomatic
epilepsy were more impaired than those with
cryptogenic epilepsy . -
pubmed
In the former group ,
patients with
mesial lesions performed worse than those with lateral lesions . -
pubmed
These findings indicated the presence of
frontal lobe dysfunction in
children with
temporal lobe epilepsy , with worse performance in those with
mesial temporal lobe epilepsy , early onset , longer duration of disease , and use of polytherapy . -
pubmed
Influenza virosomes are an efficient antigen carrier and adjuvant system that are approved for the use in
human vaccines . -
pubmed
Among 65 patients who underwent surgery for
choledochal cyst between March 1995 and June 2005 , we selected 34 adult
patients who were diagnosed as having
choledochal cyst . -
pubmed
Of the 34
patients , excision of
choledochal cyst and hepaticojejunostomy were done in 33
patients , and 1
patient with chronic
pancreatitis underwent pylorus - preserving pancreaticoduodenectomy . -
pubmed
Anastomotic
stricture and
intrahepatic duct stones postoperatively developed in eight
patients ; one
patient of 19 type I
cyst and seven
patients of 15 type IVa , developing significantly more in the type IVa choledochal
cyst ( P<0.05 ) . -
pubmed
Therefore , closed careful follow - up is important in
patients who underwent
cyst excision with hepaticojejunostomy for
type IVa choledochal cyst . -
pubmed
MATERIALS AND METHODS : Analysis included 104
patients with
MDS ( 24
refractory anemia , 32 refractory
anemia with
ringed sideroblasts , 34 refractory
anemia with excess of blasts , 7 refractory
anemia with excess of blasts in transformation to
acute leukemia , and 7
chronic myelo - monocytic leukemia ) , 3
patients with
acute myeloid leukemia from
MDS , and 36
patients with
myeloproliferative disease ( 23
chronic myeloid leukemia , 9
polycythemia vera , 4
idiopathic myelofibrosis ) . -
pubmed
Eighty percentage of such
mice developed
adenomyoepitheliomas within 53 - 88 weeks . -
pubmed
Pseudomembranous colitis , often related to
Clostridium difficile toxins ; is a severe form of
postantibiotic diarrhea . -
pubmed
Rectal
prolapsus in
children is cured without recurrence in 98 % of cases . -
pubmed
Combined primary subintimal and endoluminal angioplasty for
ischaemic inferior - limb ulcers in diabetic
patients : 5 - year practice in a multidisciplinary '
diabetic - foot ' service . -
pubmed
MATERIALS AND METHOD : Since September 2002 until December 2007 , a consecutive series of 176 limbs with manifold
ischaemic wounds in 161 diabetic
patients were treated by associated multilevel angioplasties in a multidisciplinary '
diabetic - foot team ' ( a third - line
diabetic - care institution integrating two departmental hospitals ) . -
pubmed
The 30 - day survival rate was 99 % ( one
patient died from
myocardial infarction ) . -
pubmed
METHODS : In a prospective cohort study , 116
patients with suspected unresectable
pancreatic cancer referred from peripheral hospitals ( 107 ) or our own gastroenterology department ( 9 ) were analysed . -
pubmed
CT scans from referral centres were reviewed and in case of locally advanced disease or uncertain
metastatic disease ,
patients underwent a laparoscopy to detect CT - occult
metastases . -
pubmed
Patients without
metastases were offered 5 - FU based chemoradiotherapy . -
pubmed
Locally advanced disease was confirmed in 59 ( 55 % ) patients and metastatic
disease was found in 24
patients ( 22 % ) . -
pubmed
CONCLUSION : Correct staging is difficult in
patients with suspected locally advanced
pancreatic cancer and should preferably be performed in centres with technically advanced equipment and experienced radiologists . -
pubmed
Although Toxoplasma was discovered in 1908 , it was only in the 1950s that the extent of the
infection in
humans and domestic animals was realised and work was undertaken to elucidate its life cycle ( reviewed elsewhere in this edition ) . -
pubmed
We report a case of an 56 - years old
man who abruptly presented with right upper quadrant
abdominal pain . -
pubmed
These
mice present with an elevated incidence of spontaneous histologic lesions , including
cataracts ,
hyperplasia of Brunner 's gland and mucosal
hyperplasia in the duodenum . -
pubmed
In addition ,
osteogenic tumors in
mice tails , such as
osteoma and
osteosarcoma were detected . -
pubmed
Rightward hemispheric asymmetries in auditory language cortex in
children with
autistic disorder : an MRI investigation . -
pubmed
PURPOSE : determine if
language disorder in
children with
autistic disorder (
AD ) corresponds to abnormalities in hemispheric asymmetries in auditory language cortex . -
pubmed
METHODS : MRI morphometric study in
children with
AD ( n = 50 ) to assess hemispheric asymmetries in auditory language cortex . -
pubmed
These issues of life ,
death , and consciousness are discussed in the context of Mike , the headless
chicken , who survived for 18 months , and in the context of consciousness with high degrees of intellectual and cognitive function in a congenitally anencephalic brain ; additionally , in the reanimation work of Soviet scientists in the 1920 - 30s , and in auditory sentence processing in patients in
comatose , vegetative , and
minimally conscious states . -
pubmed
SUMMARY : Postoperative radiotherapy improves survival in
patients with high - risk pathological features at radical prostatectomy at the cost of moderate
urinary and bowel toxicity . -
pubmed
Efficacy of tart
cherry juice in reducing
muscle pain during running : a randomized controlled trial . -
pubmed
Tart
cherries , rich in antioxidant and anti - inflammatory properties , may have a protective effect to reduce
muscle damage and
pain during strenuous exercise . -
pubmed
This study aimed to assess the effects of tart
cherry juice as compared to a placebo
cherry drink on
pain among runners in a long distance relay race . -
pubmed
RESULTS : While both groups reported increased
pain after the race , the
cherry juice group reported a significantly smaller increase in
pain ( 12 + /- 18 mm ) compared to the placebo group ( 37 + /- 20 mm ) ( p & lt ; .001 ) . -
pubmed
The
patients with VMA(+ ) progressive disease died later than those with VMA(- )
tumors ( P = .047 ) . -
pubmed
These results show that increased urinary VMA predicts poor outcome for
patients with favorable
tumor sites . -
pubmed
Urinary VMA can be useful risk determinant in combination with other biological determinants to predict prognosis of
patients with
localized neck , thoracic or pelvic tumors . -
pubmed
In high - risk
patients , negative
spot test or normal level of urinary VMA at diagnosis might be used for identification of a group of
patients with more favorable prognosis . -
pubmed
Furthermore , lethally irradiated
mice transplanted with E13 fetal liver cells from
Mcl-1 / Myc bitransgenic mice uniformly died of stem / progenitor cell
tumors . -
pubmed
OBJECTIVE : To study the efficacy of adjunctive
levetiracetam therapy compared with placebo in the treatment of
subjects with
depression with
bipolar disorder . -
pubmed
CONCLUSIONS :
Levetiracetam adjunctive therapy was not superior to placebo in the short - term treatment of
subjects with
depression with
bipolar disorder in the population studied . -
pubmed
On the sixth day , after delivery , the
patient was discharged
seizure - free . -
pubmed
Etanercept in the treatment of
psoriasis and
psoriatic arthritis with concomitant
hepatitis C virus infection : clinical and virological study in three
patients . -
pubmed
We describe three
psoriatic patients with
HCV , one with concomitant
alcoholic hepatitis , who were treated with
etanercept monotherapy for six months . -
pubmed
We obtained good clinical responses for both
psoriasis and
arthritis in all three
patients . -
pubmed
Our results add to accumulating data suggesting that
etanercept represents a valuable therapeutic option for treatment of
HCV - positive
psoriatic patients , with an acceptable safety profile in the short - term . -
pubmed
However , etanercept treatment of
HCV cases with concomitant
alcoholic hepatitis must be undertaken with caution . -
pubmed
bovis severely decreased the virulence of the bacteria when assessed in a progressive model of
pulmonary tuberculosis in Balb / c
mice . -
pubmed
A number of features of the pathology occurring in spontaneously
hypertensive stroke prone
rats ( SHRSPs ) , such as MRI brain signal abnormalities , the presence of high protein content in cerebrospinal fluid and vessel wall thickening , seem to indicate that this
strain is a suitable model for
cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (
CADASIL ) . -
pubmed
Climate teleconnections and recent patterns of
human and
animal disease outbreaks . -
pubmed
However , the immune status of livestock ( Rift Valley
fever ) and
human ( chikungunya ) populations is a factor that is largely unknown but very likely plays a role in the spatial - temporal patterns of these disease outbreaks . -
pubmed
The goal of this study is to validate whether the seven mRNAs and three proteins previously reported as biomarkers are capable of discriminating
patients with
oral squamous cell carcinomas (
OSCC ) from healthy subjects in independent cohorts and by a National Cancer Institute ( NCI)-Early Detection Research Network ( EDRN)-Biomarker Reference Laboratory ( BRL ) . -
pubmed
Lastly , one of our
patients died from an aggressive endometrioid
ovarian bilateral tumour associated with an
endometrial adenocarcinoma . -
pubmed
Cytology and
human papillomavirus testing 6 to 12 months after
ASCUS or LSIL cytology in organized screening to predict high - grade
cervical neoplasia between screening rounds . -
pubmed
Between January 2005 and April 2008 , 692 study women with screening - detected
ASCUS / LSIL cytology 6 to 12 months earlier returned for
HPV mRNA and DNA testing and repeat cytology . -
pubmed
In conclusion , both positive
HPV mRNA and DNA test results have a high enough long - term prediction of CIN2 + risk to consider referral to colposcopy as good practice when performed in delayed triage of women with
ASCUS / LSIL cytology . -
pubmed
Does preoperative
atrial fibrillation portend a poorer prognosis in
patients undergoing isolated aortic valve replacement ? -
pubmed
Patients who underwent concomitant
atrial arrhythmia surgery / ablation were excluded . -
pubmed
Preop -
AF patients were generally older ( mean age , 73 vs 68 years ; P & lt ; 0.001 ) and presented more often with comorbidities including
congestive heart failure ,
diabetes , and
cerebrovascular disease ( all P & lt ; 0.05 ) . -
pubmed
There was a trend toward increased 30 - day mortality in
patients with preop -
AF on multivariate analysis ( P = 0.051 ) . -
pubmed
Using these nanoparticles , we successfully imaged lymphatic networks and vasculature of xenografted
tumours in living
mice . -
pubmed
inhibited carrageenan - induced
rat paw
oedema ( P & lt ; 0.001 ) . -
pubmed
Cardiotoxicity to these drugs is not an uncommon adverse effect and has been reported in 1%-18 % of
patients . -
pubmed
We describe here the case of a 55 - year - old
man who presented with
cardiogenic shock and ECG signs of ST - elevation
myocardial infarction . -
pubmed
We measured quality of life ( QOL ) among individuals receiving treatment for
human immunodeficiency virus (
HIV ; n = 45 ) , active
tuberculosis (
TB ; n = 44 ) and both
TB and
HIV ( n = 9 ) in Rio de Janeiro , Brazil . -
pubmed
Rapid resolution of
acute subdural hematoma in
child with severe
head injury : a case report . -
pubmed
CASE PRESENTATION : A 7 - year - old Asian
girl with
traumatic acute subdural hematoma was transferred to our hospital for an emergency operation based on the results of an initial computed tomography scan and neurological examination . -
pubmed
The
patient was discharged with mild
confusion 40 days after the admission . -
pubmed
CONCLUSION : A follow - up computed tomography scan is strongly recommended before surgery when a
child with a severe
head injury presents with any sign of neurological improvement , especially with a mixed density
hematoma on the initial computed tomography scan . -
pubmed
Neuropsychiatric symptoms in elderly
inpatients : a multicenter cross - sectional study . -
pubmed
BACKGROUND / AIMS : We determined the prevalence of
neuropsychiatric symptoms in geriatric rehabilitation
patients to compare neuropsychiatric symptoms between
patients with and without
dementia , and to evaluate associations linking severity of
cognitive impairment and
neuropsychiatric symptoms . -
pubmed
RESULTS : Of the 194
patients , 149 ( 76.8 % ) had
dementia , and 154 ( 79.4 % ) had exhibited at least one neuropsychiatric symptom during the past week . -
pubmed
CONCLUSION : The prevalence of
neuropsychiatric symptoms among geriatric rehabilitation
patients was high but not higher than in elderly
outpatients . -
pubmed
BACKGROUND :
Human embryonic stem cells ( hESCs ) serve as a potential unlimited ex vivo source of cardiomyocytes for disease modeling ,
cardiotoxicity screening , drug discovery , and cell - based therapies . -
pubmed
BACKGROUND : Prevention of
post - spinal hypotension in obstetric
patients can be accomplished using intravenous fluid expansion and prophylactic use of sympathomimetic drugs . -
pubmed
Reactive
hypertension occurred in one
patient ( 2.2 % ) and
bradycardia in two
patients ( 4.4 % ) in Group A. -
pubmed
Six
patients complained of
nausea in Group B ( 13.3 % ) compared to one in Group A. -
pubmed
Uncovering and dissecting the
genotoxicity of self - inactivating
lentiviral vectors in vivo . -
pubmed
Vaccines to prevent
Trypanosoma cruzi infection in
humans or animals are not available , and in many settings ,
dogs are an important source of
domestic infection for the insect vector . -
pubmed
Outcomes with
abiraterone acetate in metastatic castration - resistant
prostate cancer patients who have poor performance status . -
pubmed
BACKGROUND : Although
abiraterone acetate (
abiraterone ) has proven efficacy in two randomised phase 3 trials in
metastatic castration - resistant prostate cancer (
mCRPC ) ,
patients who had an Eastern Cooperative Oncology Group ( ECOG ) performance status ( PS ) & gt;=2 were either excluded or under - represented in these trials . -
pubmed
OBJECTIVE : To compare outcomes in ECOG PS 0 - 1 and & gt;=2 in
mCRPC patients treated with
abiraterone . -
pubmed
DESIGN , SETTING , AND PARTICIPANTS :
Cancer registries from three Canadian centres were used to retrospectively identify
mCRPC patients (
postdocetaxel and
docetaxel - naive ) treated with
abiraterone . -
pubmed
PATIENT SUMMARY : We found that advanced
prostate cancer patients who have worse performance status ( PS ) derive less benefit from
abiraterone , indicating that earlier treatment before PS declines could improve outcomes . -
pubmed
Transarterial treatments , frequently provided in an outpatient setting , are now safely and effectively being applied to
patients with even advanced
malignancy or partially decompensated
cirrhosis . -
pubmed
The article deals with a case of comparison of apneic oxygenation ( AO ) and high frequency jet ventilation ( HFJV ) during double level tracheal resection and reconstruction in
patient with multifocal
tracheal stenosis and underlying
cerebral trauma . -
pubmed
These observations evident about the necessity to study the role of
hyperoxia ,
hypercapnia and
cerebral hyperemia in
patients with underlying
cerebral trauma undergoing tracheal resection and reconstruction . -
pubmed
Retraction notice to "
PBOX-15 induces apoptosis and improves the efficacy of
oxaliplatin in
human colorectal cancer cell lines " [ Eur . -
pubmed
DESIGN : This study enrolled 30
children with
ASD and 19 healthy
children . -
pubmed
Twenty - one ( 35.6 % )
patients had
intrinsic sphincter deficiency (
ISD ) . -
pubmed
Procedures for
prolapse were done in four ( 6 % )
patients . -
pubmed
Leiomyomas and matched
normal myometrium from each
woman were analyzed in vitro . -
pubmed
METHODS : We gathered clinical and imaging data of 336 young
ICH patients between age 16 and 49 treated in the Helsinki University Central Hospital . -
pubmed
METHODS : 100 female
patients with
AUB were enrolled in the study . -
pubmed
MATERIALS AND METHODS :
Patients aged & lt;18 years who underwent PNL for
renal stones of sizes 10 - 20 mm between August 2011 and March 2014 in 3 referral centers were reviewed retrospectively . -
pubmed
We also designed an experiment to investigate the location of iRGD - modified SSL when co - administered with free iRGD or free RGD to
B16 - F10 tumor bearing
nude mice . -
pubmed
This study was to investigate the effect of Nidus Vespae decoction ( NVD ) on
tumor cell viability and immunoregulating functions of
human peripheral blood immune cells . -
pubmed
The majority of
patients were male ( range , 50 % to 74 % ) , and & lt;10 % had
structural heart disease . -
pubmed
In the randomized controlled trial component of the dual - design study , the 5 - year Kaplan - Meier estimates of the incidence of
arrhythmic events were 7 % among
patients who underwent ablation and 77 % among
patients who did not undergo ablation ( relative risk reduction : 0.08 ; 95 % confidence interval : 0.02 to 0.33 ; p<0.001 ) . -
pubmed
In the observational cohorts of asymptomatic
patients who did not undergo catheter ablation ( n=883 , with follow - up ranging from 8 to 96 months ) , regular
supraventricular tachycardia or benign
atrial fibrillation ( shortest RR interval & gt;250 ms ) developed in 0 % to 16 % , malignant
atrial fibrillation ( shortest RR interval & lt;=250 ms ) in 0 % to 9 % , and
ventricular fibrillation in 0 % to 2 % , most of whom were children in the last case . -
pubmed
CONCLUSIONS : The existing evidence suggests risk stratification with an electrophysiological study of
patients with asymptomatic pre - excitation may be beneficial , along with consideration of accessory - pathway ablation in those deemed to be at high risk of future
arrhythmias . -
pubmed
Distal coronary embolization following acute
myocardial infarction increases early
infarct size and late left ventricular wall thinning in a
porcine model . -
pubmed
The aims of this study were to evaluate the effects of
DCE sufficient to cause no - reflow on
infarct size , cardiac function and
ventricular remodeling in a
porcine acute myocardial infarction model . -
pubmed
Awakening Blood Pressure Rise in a
Patient with
Spinal Cord Injury . -
pubmed
CASE REPORT : We report the case of a 66 - year - old
man with a history of
spinal cord injury , and who had remarkable awakening BP rise in ambulatory BP monitoring . -
pubmed
Hookworms are recognised as a cause of
iron - deficiency anaemia in endemic areas . -
pubmed
[ Relationship between myocardial microRNA-30a expression and
myocardial fibrosis in
rats post
myocardial infarction ] . -
pubmed
METHODS :
Rats were randomly divided into 1 week
MI group ( n=11 ) , 2 weeks
MI group ( n=13 ) and 4 weeks
MI group ( n=15 ) by applying random number table after left anterior descending coronary artery ligation . -
pubmed
In the present study we have used
zebrafish embryos to model
Cronobacter infections in vivo using wild type and genetically engineered
strains . -
pubmed
Second , a 25 - year - old
man with
polyostotic disease of the left leg who received both surgical and medical treatment . -
pubmed
Objective measures that detect changes in neurological function in
FA patients are needed to facilitate therapeutic clinical trials . -
pubmed
The effect of
epicatechin on oxidative stress and
mitochondrial damage induced by
homocycteine using isolated
rat hippocampus mitochondria . -
pubmed
In this study , we have evaluated the effects of
epicatechin ( EC ) on
mitochondrial damage induced by
homocycteine (
Hcy ) using isolated
rat hippocampus mitochondria in vivo . -
pubmed
Effects of Acupuncture on
1 - chloro-2,4 - dinitrochlorobenzene - induced
Allergic Contact Dermatitis in
Mice . -
pubmed
BALB / c
mice received
1 - chloro-2,4 - dinitrobenzene (
DNCB ) application to build
AD - like model . -
pubmed
Background : The progression of
human African
trypanosomiasis from the early hemolymphatic stage to the late
meningoencephalitic stage is of critical diagnostic importance as it determines the choice of potentially toxic drug regimens . -
pubmed
The Treatment of
Cataract in
Children . -
pubmed
MATERIALS AND METHODS : In this study , 10
adults with
disc displacement and painful ,
hypermobile TMJ were selected . -
pubmed
Patients with
rheumatoid arthritis and parafunctional habits such as teeth clenching and grinding and biting of the cheeks or any other objects and those who had undergone surgery were excluded from this study . -
pubmed
METHODS : The British Columbia Hepatitis Testers Cohort ( BC - HTC ) includes ~1.7 million individuals tested for
HCV /
HIV or reported
HBV /
HCV /
HIV /
tuberculosis cases in BC from 1990 to 2015 , linked to administrative datasets including physician visit , hospitalization and prescription drug records . -
pubmed
A 63 - year - old
man developed a
syndrome of cauda equine , with the
numbness which is a left lower extremity from the left buttocks ,
weakness of left leg , and a
dysfunction of bladder and bowel . -
pubmed
Infective endocarditis due to
Burkholderia cepacia in a neonate : a case report . -
pubmed
METHODS : A double blinded randomised control trial was performed that included mandibular primary molars in
children of age 4 - 7 years with
pulp necrosis . -
pubmed
RESULTS : Fifteen
patients with
PCL were diagnosed during the study period ; fourteen had second trimester scans . -
pubmed
Anomalies of the CC were evident in 8/14
patients during the 2nd trimester scan and included : short length ( n = 4 ) , increased thickness ( n = 1 ) , complete agenesis ( n = 2 ) and partial agenesis ( n = 1 ) . -
pubmed
One
child was diagnosed with
attention deficit disorder . -
pubmed
Here , we compare the repeatability and reliability of exploratory behaviors between
zebrafish strains selectively bred to display contrasting behavioral responses to stressors that represent the proactive - reactive axis . -
pubmed
Reactive
zebrafish generally showed the highest reliability and repeatability of exploratory behavior compared to proactive
zebrafish and a separate wild caught
strain . -
pubmed
We did a meta - analysis including 8 clinical trials to verify the efficacy and safety of
blinatumomab in
patients with
relapsed / refractory ALL and
NHL . -
pubmed
ALL patients manifested better therapeutic response than
NHL patients and a reduced
tumor load favored the clinical response . -
pubmed
METHODS : From March 2009 to December 2014 , 285
patients presented with
type B aortic dissection . -
pubmed
Computed tomography angiography before discharge showed complete
thrombosis of the false lumen of the descending aortic in 34
patients . -
pubmed
Three
patients died during follow - up : 1 died in a traffic accident and 2 died of
sudden death . -
pubmed
CONCLUSIONS : For
patients with complicated type B
aortic dissection , implantation of a stent graft under direct vision ( hybrid surgery ) is easily performed and provides satisfactory middle- and long - term outcomes . -
pubmed
To our knowledge , this is the first report of
powdery mildew caused by Oidium anamorph of
E. - pubmed
( v ) In all
patients with
FPHL , assessment of a possible
androgen excess is mandatory . -
pubmed
Molecular remissions are observed in
chronic adult T cell leukemia /
lymphoma in
patients treated with
mogamulizumab . -
pubmed
Combination Effect of Titrated Extract of
Centella asiatica and
Astaxanthin in a
Mouse Model of
Phthalic Anhydride - Induced
Atopic Dermatitis . -
pubmed
We investigated the therapeutic efficacy of the ointment form of TECA ,
AST and a TECA +
AST combination in a
mouse model of
AD to see whether a combination of the reduced doses of 2 compounds could have a synergistic effect . -
pubmed
METHODS : An
AD - like lesion was induced by the topical application of 5 % PA to the dorsal ear and back skin of an Hos : HR-1
mouse . -
pubmed
Patients were classified into three subgroups :
EOPE ,
LOPE , and control groups . -
pubmed
The optimal treatment strategies and outcomes of
patients with metastatic
ACC remain areas of active interest . -
pubmed
We retrospectively reviewed
patients with
ACC who were treated with systemic therapy between January 1997 and October 2016 at The Ohio State University Comprehensive Cancer Center . -
pubmed
We identified 65
patients diagnosed with
ACC during the given time period , and 36
patients received systemic therapy for distant metastatic disease . -
pubmed
Six
patients with
liver metastases treated with systemic therapy who received liver - directed therapy with either transarterial chemoembolization ( TACE ) or selective internal radiation therapy ( SIRT ) had longer survival than those who did not ( p = 0.011 ) . -
pubmed
Our data expands the knowledge of clinical characteristics and outcomes of
patients with
ACC and suggests a possible role for incorporating liver - directed therapies for
patients with hepatic
metastases . -
pubmed
This is due to increasing survival rates among
patients with
metastatic disease , early detection as a result of increasing availability of spinal MRI , the recognition of the oligometastatic state as a distinct sub - group of favorable metastatic
patients and the advent of stereotactic body radiotherapy ( SBRT ) . -
pubmed
As a result , the multidisciplinary evaluation of cases prior to SBRT is emphasized with the intent to identify
patients who could benefit from surgical stabilization or down - staging of
epidural disease . -
pubmed
Cisplatin (
CDDP)-based chemotherapy is a standard strategy for the clinical treatment of
patients with
bladder cancer (
BC ) . -
pubmed
PURPOSE : The aim of this study was to test the antiviral effectivity of
potassium peroxymonosulfate (
RUBYSTA ,
KYORIN ) against five epidemic
keratoconjunctivitis - related types of
Human adenovirus D in vitro . -
pubmed
Overall ,
potassium peroxymonosulfate demonstrated sufficient inactivation of the major epidemic
keratoconjunctivitis - causing
Human adenovirus D to be considered for disinfection and prevention purposes in ophthalmological clinics and hospitals . -
pubmed
Role of turmeric extract in minimising
mucositis in
patients receiving radiotherapy for
head and neck squamous cell cancer : a randomised , placebo - controlled trial . -
pubmed
OBJECTIVE : To determine the role of turmeric extract in reducing
mucositis in
patients undergoing radiotherapy for
head and neck cancer . -
pubmed
All
patients were assessed for
oral mucositis on a weekly basis during treatment and two months post - treatment using the National Cancer Institute Common Terminology Criteria for Adverse Events and World Health Organization criteria . -
pubmed
The severity of
mucositis was progressive in the control group , with four
patients developing grade 3
mucositis by week four . -
pubmed
In group A , however , the majority of
patients ( 73.3 per cent ) had grade 1
mucositis after four weeks of treatment . -
pubmed
CONCLUSION : Turmeric extract reduces the incidence and severity of radiation - induced
mucositis , which can benefit
patients undergoing radiation for
head and neck cancer . -
pubmed
Liver Stiffness Measurement by Vibration Controlled Transient Elastography Does Not Correlate to Hepatic
Iron Overload in
Children With
Sickle Cell Disease . -
pubmed
CONCLUSION : VCTE is a noninvasive technology that is feasible in
children with
SCD . -
pubmed
METHODS : Data for
patients with
malignant neoplasms of the oral cavity registered in the Cancer Registry Database of Taipei Veterans General Hospital between 2002 and 2011 were retrieved . -
pubmed
RESULTS : A total of 191
OSCC patients were included for retrospective analysis ; 177 were
males and 14 were females . -
pubmed
Patients with
diabetes , moderate or poor cell differentiation , perineural invasion , and extracapsular spread presented lower 5 - year OS rates ( HR=1.87 , 1.65 , 2.42 , and 2.14 , respectively ) , and
patients with perineural invasion , positive cut margin , and extracapsular spread presented lower 5 - year DFS rates ( HR=1.57 , 1.62 , and 1.71 , respectively ) . -
pubmed
We present a single - patient study in which a
patient with
Parkinson ' s disease traversed a doorway under different cueing conditions . -
pubmed
Omalizumab in
children and adolescents with chronic spontaneous
urticaria : case series and review of the literature . -
pubmed
We reported our experience of six
patients with
chronic spontaneous urticaria (
CSU ) treated with
omalizumab . -
pubmed
Thus far , two
patients have experienced a complete
CSU regression over 12 months after the final
omalizumab administration . -
pubmed
Quantitative characterization of the PVSV morphology in MRI images in healthy subjects may serve as a reference for detecting disease related
PVS and/or blood vessel alterations in
patients with
brain diseases . -
pubmed
CASE PRESENTATION : Our patient was a 39 - year - old Ethiopian
man who presented with left - side body
weakness of 6 years ' duration with worsening of symptoms of 6 months ' duration . -
pubmed
The
patient was reoperated for
tension pneumocephalus 48 hours after the initial surgery . -
pubmed
Severe acute respiratory syndrome - coronavirus 2 (
SARS - CoV-2 ) has rapidly caused a global pandemic associated with a novel
respiratory infection :
coronavirus disease-19 ( COVID-19 ) . -
pubmed
In
teleost fishes ,
reptiles and
birds , the biology of
light sensitivity is more complicated as cells and tissues can be directly light responsive . -
pubmed
In the case of
teleosts , in particular the
zebrafish model system , not only do peripheral tissues have a circadian pacemaker , but possess clear , direct
light sensitivity . -
pubmed
BACKGROUND :
Aortic aneurysms occur concomitantly with
malignancy in approximately 1.0 - 17.0 % of
patients . -
pubmed
METHODS :
Patients with
aortic aneurysms , with and without
malignancy between 2005 - 2017 were identified within institutional databases using Current Procedural Terminology and International Classification of Disease codes . -
pubmed
Inclusion criteria included complete chemotherapy documentation , a minimum of three multiplanar axial / coronal imaging or ultrasonography prior to , during , and after receiving therapy or two studies for
patients without
malignancy . -
pubmed
RESULTS : 159 ( 172
aneurysms )
patients with
malignancy and 127 ( 149
aneurysms )
patients without
malignancy were included . -
pubmed
Average
patient demographics were : 74.4 + -9.8 - years - old , Caucasian ( 66.8 % ) , male ( 70.3 % ) , with
hypertension ( 71.1 % ) , current smoking ( 24.5 % ) ,
coronary atherosclerotic disease ( 26.2 % ) , and
AAA ( 71.0 % ) . -
pubmed
CONCLUSION : Small aortic
aneurysms with concomitant
malignancies are discovered at smaller initial sizes , grow at similar rates , require fewer interventions , and have fewer
ruptures and acute dissections than
patients without
malignancy . -
pubmed
Patients with concomitant disease can be confidently prescribed to standard institutional
aneurysm surveillance protocols . -
pubmed
Overall , we recommend treatment of the
malignancy prior to small aortic
aneurysm repair as these
aneurysms behave similarly to those in
patients without
malignancy . -
pubmed
Incidence and Clinical Impact of Inflammatory
Fluorodeoxyglucose Positron Emission Tomography Uptake After Neoadjuvant Pembrolizumab in
Patients with Organ - confined
Bladder Cancer Undergoing Radical Cystectomy . -
pubmed
METHODS : After a 4 - week lead - in phase ( baseline ) , 9
men and 12 postmenopausal
women ( 50 - 75 years ) with
chronic inflammation received two phases of 10 - week supplementation with 3 g / day
EPA and
DHA in a random order , separated by a 10 - week washout . -
pubmed
To elucidate the mechanisms of
memory impairment after chronic neonatal intermittent
hypoxia (
IH ) , we employed a
mice model of severe
IH administered at postnatal days 3 to 7 . -
pubmed
Surface kymography in three planes were performed in 180
patients following
myocardial infarcts , and these were compared with the results of coronary angiography and selective laevocardiography . -
pubmed
Of the 12
patients treated , 11 had measurable
tumor criteria and 5 of these responded to treatment . -
pubmed
An antiserum has been found in a nonimmunized
rabbit which reacts strongly with a system of filaments in various fibroblasts , epithelial cells , macrophages and
neuroblastoma . -
pubmed
A new mechanism of myelopathic changes in
patients with
mucopolysaccharidosis is described . -
pubmed
Myelography is indicated in the evaluation of these
patients because surgical decompression may reverse the progressive
neurological deficits . -
pubmed
The theoretical concept is supported by experimental findings in
frog tadpoles with " congenital "
dislocation of the knee joint produced by osteolathyrogenic diet . -
pubmed
The suggested pathogenetic mechanism appears to apply even to the
congenital dislocation of the hip in
man . -
pubmed
Gestational hyperlipidemia in the
rat is characterized by accumulation of n - 6 and
n - 3 fatty acids , especially
docosahexaenoic acid . -
pubmed
Compared to non - pregnant
rats , gestational
hyperlipidemia was also associated with a lower proportion but similar quantity of
linoleic acid in maternal carcass and adipose stores . -
pubmed
We conclude that
gestational hyperlipidemia in the
rat is characterized by a relative but not quantitative decrease in whole - body stores of
n - 6 fatty acids and a marked proportional and quantitative increase in
docosahexaenoic acid in maternal organs and in the conceptus . -
pubmed
[ Enhancement effect of fat emulsion for intravenous use (
intralipos ) on the growth of a
human breast cancer cell line in culture : preliminary report ] . -
pubmed
Gallid herpesvirus 1 (
infectious laryngotracheitis virus ): cloning and physical maps of the SA-2
strain . -
pubmed
In our environment , some children with
allergic respiratory pathology do not have as favorable an evolution as expected after three years of immunotherapy with
D. - pubmed
There were 38
boys ( 76 % ) and 12
girls ( 24 % ) with
rhinitis and
bronchial asthma . -
pubmed
Two symptomatic and two asymptomatic complications arose , including permanent
hemiparesis in one
patient . -
pubmed
Bifurcation and linear antibacterial prostheses were used in 9
patients with a high risk of
suppuration verified by cultures of discharge from
ulcers and lymph nodes , and the presence of
lymphangitis and
lymphadenitis . -
pubmed
The effect was positive in 8
patients , 2 of them had superficial
suppuration of the operative
wounds . -
pubmed
The effects of dietary counselling on food and nutrient intake and
weight loss were studied over a two - year period in 32
obese children ( relative weight greater than 120 % ) with intensive treatment ( Group I ) and in 16
obese children treated in a school health - care setting ( Group II ) . -
pubmed
The
obese children were treated for one year and observed for another year . -
pubmed
The decrease in energy intake was significantly correlated with the reduction in body fat mass over the first year ( rs = 0.50 ; P = 0.05 , n = 16 ) in
obese children passing through their pubertal growth spurt and to the reduction in relative weight over the first year ( rs = 0.90 ; P less than 0.05 , n = 5 ) , as well as to the decrease in fat mass over the second year ( rs = 0.70 ; P less than 0.05 , n = 11 ) in adolescents beyond their growth spurt . -
pubmed
[ Characteristics of the cardiovascular system in
children with
primary arterial hypotension ] . -
pubmed
Overall 120
children aged 12 to 15 years with primary
arterial hypotension and different variants of the disease course ( grave , of medium gravity or mild ) were examined . -
pubmed
Both
patients had an
eosinophilia ( 10.5 and 19 % ) and specific antibodies against
Onchocerca volvulus . -
pubmed
Microfilaria were demonstrated in the skin of the younger
man . -
pubmed
447
children between 0 and 24 months with
diaper dermatitis were treated by topical application of Parfenac - Fettsalbe (
Bufexamac ) . -
pubmed
Very good ( no efflorescences remaining ) and good results ( some remaining efflorescences ) were thus found in more than 80 % of
patients treated : with respect to
corticosteroid advoidance this can be regarded as an effective antiphlogistic medication for
diaper dermatitis . -
pubmed
Psychopathology and plasma
cortisol responses to
dexamethasone in prepubertal
psychiatric inpatients . -
pubmed
This study of 51 prepubertal
psychiatric inpatients evaluates plasma
cortisol measurements at 8 AM , 4 PM , and 11 PM before and after
dexamethasone was administered in counterbalanced order at doses of 0.5 mg and 1.0 mg . -
pubmed
Approximately 76.5 % of the
children had an
affective disorder . -
pubmed
Bovine leukaemia virus and
enzootic bovine leukosis . -
pubmed
Infection of bovines with bovine leukaemia virus (
BLV ) manifests itself in either of two ways : 30 - 70 % of carriers develop
persistent lymphocytosis (
PL ) , with the viral genome integrated at a large number of different sites in the DNA of the affected B - lymphocytes , without causing any
chromosomal abnormalities . -
pubmed
Although
bovine leukosis is not of major economic importance , its eradication is desirable and feasible in countries with a relatively low incidence , by means of testing and elimination . -
pubmed
It is proposed that multicenter collaborative studies be designed to evaluate proposed therapies for
children with
IgAN associated with
proliferative glomerular lesions , particularly those in whom
hypertension ,
proteinuria , and depressed
glomerular filtration rate are found . -
pubmed
We report a
patient with
sudden memory dysfunction following
hemorrhage into the anterior nucleus of the left thalamus that was shown neuropathologically to disrupt the mamillothalamic fasciculus , one of the principal components of the limbic system . -
pubmed
The toxicity of
1 -[ 2 -( diethylamino ) ethyl ] reserpine (
DL-152 ) has been measured for 4 transplantable
mouse tumors . -
pubmed
DL-152 was found to be toxic to cells of all the
tumor models tested (
KHT fibrosarcoma ,
RIF-1 fibrosarcoma ,
EMT-6 adenocarcinoma and
Lewis lung carcinoma ) when the drug was given by intraperitoneal injection to the
tumor - bearing
mouse and cell survival was measured by excision assay . -
pubmed
Hyperthermia ( temperature of at least 40.5 degrees C for at least one hour ) associated with
drug intoxication was identified in 12
patients over a 5 - yr period . -
pubmed
Hyperthermia was present in four
patients on admission , but its onset was delayed up to 12 h in the remainder . -
pubmed
Outcome of hyperthermic
patients was poor : five died and four had severe permanent
neurologic sequelae . -
pubmed
Clinical signs common to
patients who developed
hyperthermia were increased muscular activity and absence of sweating . -
pubmed
Five
patients suffered
seizures , and four did not respond to anticonvulsant medication until body temperature was lowered . -
pubmed
Both serum
cholesterol and
triglyceride levels are initially decreased in
patients aged 50 to 69 with
cerebral infarction , whereas only
cholesterol is decreased in
patients 60 to 69 with
transient ischemic attacks . -
pubmed
Influence of
estrogen administration on
tumor characteristics and survival in
women with
cutaneous melanoma . -
pubmed
A prospective study on 289
women with clinical stage I cutaneous
melanoma was done to determine the relationship between
estrogen administration ,
tumor characteristics , and survival . -
pubmed
Eighty - two
women took
oral contraceptives (
OC ) and 44 took menopausal
estrogens ( MPE ) prior to the diagnosis of
melanoma . -
pubmed
A PSE-4 - producing
Escherichia coli strain was resistant to
Sch 34343 . -
pubmed
Pharmacokinetics of
tocainide in
patients with severe
renal failure . -
pubmed
to 20
patients with
renal failure due to various causes , and to 8 healthy controls . -
pubmed
The peak plasma concentrations in the
patients with
pyelonephritis ( 3.80 micrograms / ml ) and
interstitial nephritis ( 3.74 micrograms / ml ) but not in those with
glomerulonephritis ( 3.17 micrograms / ml ) differed from that in healthy volunteers ( 3.24 micrograms / ml ) . -
pubmed
The predictive value positive of serum
iron studies and erythrocyte indices in differentiating between
iron deficiency anemia and the
anemia of chronic disease (
ACD ) were determined in 82 hospitalized
patients with an
iron - binding saturation of 15 percent or less . -
pubmed
Iron deficiency was present in 83 percent of
patients with a mean corpuscular volume ( MCV ) of 75 microns3 or less , but only 2 percent of patients with an MCV of 86 microns3 or greater . -
pubmed
The therapeutic activity of
cisplatin was explored in three consecutive
patients with locoregional
squamous cell carcinoma of the anus who received no prior therapy . -
pubmed
Study of
mucopolysaccharides in experimental
conjunctival diphtheria of the
guinea pig ] . -
pubmed
[ Current importance in the treatment of
bronchitis with
sulfonamides in
children ] . -
pubmed
[ Specificity of
vertebral compression fractures in
children ] . -
pubmed
[ Serum and erythrocyte
electrolytes in
children with
cardiac arrhythmias ] . -
pubmed
Microcirculatory changes and general responses to
5 - hydroxytryptamine in normothermic and
hypothermic mice . -
pubmed
Spontaneous
rupture of the stomach in a healthy adult
man after
sodium bicarbonate ingestion . -
pubmed
The group was compared with three others ( 1 ) 113 healthy subjects , untested for acetylator phenotype , ( 2 ) 16 slow - acetylator
hypertensive patients treated with
hydralazine for more than a year without developing
SLE , and ( 3 ) 20 patients with idiopathic
SLE . -
pubmed
Periarteritis nodosa in spontaneously
hypertensive rats -- immunohistological study and permeability test . -
pubmed
Spontaneously
hypertensive rats develop
periarteritis nodosa spontaneously with high incidence . -
pubmed
This fact suggests that
periarteritis nodosa in spontaneously
hypertensive rats may not be
arteritis of immune complex type . -
pubmed
In male spontaneously
hypertensive rats periarteritis nodosa is observed in 6 of 11 and the arterial permeability increases more pronouncedly in the positive group , whereas 5 female spontaneously
hypertensive rats of various ages are free from
periarteritis nodosa irrespective of high arterial permeability . -
pubmed
Therefore , high arterial permeability does not always lead to regular development of
periarteritis nodosa especially in female spontaneously
hypertensive rats . -
pubmed
Regrowth of
aminoglycoside - resistant variants was seen when large inocula of two
strains of
Escherichia coli were incubated with
gentamicin in concentrations well above their MICs ( 0.5 micrograms / ml ) . -
pubmed
[ Agar cultures of blood forming cells from
patients with various forms of
hemopoietic dysplasia ] . -
pubmed
The leukemic growth type was proved in 59 % of the
patients with
haematopoietic dysplasia . -
pubmed
1 Fifty - seven
patients with mild or moderate
essential hypertension , mean age 50 ( range 31 - 69 ) were randomised to treatment with either
captopril or
atenolol . -
pubmed
5 Two
patients were excluded from the
captopril group , one because of a reversible
loss of taste and the other because of
dizziness . -
pubmed
Three
patients were excluded from the
atenolol group , two because of
bradyarrhythmias and one because of inadequate blood pressure response . -
pubmed
The selective
toxicity of gonococcal lipopolysaccharide for the mucosa of
human fallopian tubes , which is demonstrated in these studies , may be responsible in part for the specificity of naturally occurring
gonococcal infections for
humans . -
pubmed
Two
patients developed antepartum
pulmonary edema after receiving
hydrocortisone to promote fetal lung maturity . -
pubmed
The third
patient developed
pulmonary edema shortly after delivery and after having received glucocorticoids antepartum . -
pubmed
The stimulatory effect of a recently introduced saliva substitute (
Saliment ) on the parotid salivary secretion was experimentally investigated in 10 healthy
individuals without signs or symptoms of
xerostomia and in 11
patients with
xerostomia due to
Sjogren ' s syndrome . -
pubmed
Further , in 15
patients with
Sjogren ' s syndrome , the effect of Saliment on the sensation of
xerostomia was examined in a double - blind clinical study with cross - over . -
pubmed
Anergy and altered lymphocyte function in the injured
patient . -
pubmed
The immunologic competence of 16
patients , including 15 who had minor
injuries and required less than 4 transfusions , was prospectively studied with skin testing , leukocyte counts , and protein electrophoresis . -
pubmed
Ten
patients with minor
trauma responded to at least one of the antigen skin tests and were considered nonanergic ( NA ) . -
pubmed
Lipoprotein levels and tissue lipids in
fatty - fibrous atherosclerosis induced in
rabbits by two years '
cholesterol feeding at a low level . -
pubmed
A group of 12 young NZW
rabbits of the same breeding
strain were fed a diet enriched with 0.1 %
cholesterol by weight . -
pubmed
Two
animals that died during this period showed no gross or microscopic
atherosclerosis . -
pubmed
In some
animals this resulted in moderate
hypercholesterolaemia . -
pubmed
One
animal that died at this time showed no
atherosclerosis with a mean serum
cholesterol level of 224 mg / dl . -
pubmed
This resulted in definite
hypercholesterolaemia in some
animals , but a few resisted the treatment with mean serum
cholesterol levels around 40 - 60 mg / dl . -
pubmed
In general ,
animals with established
hypercholesterolaemia showed severe
atherosclerosis , but often of a more fibrous and less cellular nature than is usual in the
rabbit . -
pubmed
A reappraisal of the
dog - heart
infarct plasmalogen , its conception as a
bis - phosphatidic acid and current recognition as an
N - acyl phosphatidyl ethanolamine . -
pubmed
We have re - examined the lipids from
myocardial infarcts of
cat ,
dog ,
rabbit and
man , mainly through TLC methods , and confirm the identity of
cat and
dog "
infarct plasmalogen " as an
N - acyl phosphatidyl ethanolamine (
NAPE ) . -
pubmed
This substance was not detected in
infarcts of
rabbit and
man . -
pubmed
The hypothalamo - neurohypophyseal function was evaluated in a
patient with the chronic
hypernatremia syndrome . -
pubmed
In newborn
piglets , moderate increases in
sodium excretion by
acetazolamide were accompanied by a marked
kaliuresis . -
pubmed
Serum was obtained from 7
patients with
solid tumor , 12
patients with
malignant CNS tumor , and 16
patients with
acute leukemia . -
pubmed
Immunocompromised patients are at risk of developing
infections caused by
Rhodococcus equi , a gram - positive bacillus that can cause
pneumonia in patients with
acquired immunodeficiency syndrome . -
pubmed
Infection with
R equi may go unrecognized by pathologists unaware of its presentation and appearance in cytologic material . -
pubmed
Combined kidney - pancreas transplantation has become the treatment of choice for many
patients with end - stage
diabetic nephropathy . -
pubmed
Pancreas transplantation ( PTx ) alone is an option for
type I diabetic patients without end - stage
diabetic nephropathy . -
pubmed
Knowledge of factors contributing to or predicting the rate of
renal deterioration ( including the effect of
CsA on the
patient 's renal function before transplantation ) is necessary to determine candidacy for either kidney - pancreas transplantation or PTx alone . -
pubmed
To address this issue , we selected 12 pre -
uremic patients with
creatinine clearances ( CrCl ) above 40 ml / min and less than 100 ml / min to participate in a 6 - week oral
CsA challenge test . -
pubmed
The effects of oral micronized
progesterone - administered at a low dose - on the endometrium and on
bleeding pattern have been evaluated during a multicenter study in which 101
patients were involved . -
pubmed
For a minimum of 6 months ,
patients who did not wish to have withdrawal
bleeding ( 98 ) received the association of
17 beta - percutaneous estradiol ( 1.5 mg / d ) and oral micronized
progesterone ( 100 mg / d , at bedtime ) during 25 days per month ( or 21 d/28 ) . -
pubmed
The few
women ( 3 ) who wished regular
bleeding were given
progesterone ( 300 mg / d ) with
estradiol ( 3 mg / d ) , from the 16th to the 25th of the month . -
pubmed
This situation makes it possible to minimize spottings and to maintain an
amenorrhea in the majority of
patients , thus letting us hoping for an improvement in the observance of this simplified therapy . -
pubmed
A phase III trial was conducted in 40
patients with known or suspected
skull base tumors to evaluate the safety and efficacy of high - dose
gadodiamide injection for use as a paramagnetic contrast medium in conventional and dynamic magnetic resonance ( MR ) imaging . -
pubmed
In
patients who present with unheralded
myocardial infarction both the severity and the extent of
coronary atherosclerosis appear to be less than that in patients with
chronic stable angina , thus suggesting that , in the latter , protective factors may prevent or delay the evolution towards
acute coronary syndromes . -
pubmed
Therefore , risk factors were compared in 88 consecutive
patients ( 73
men ; mean age 56 + /- 9 years ) with unheralded
myocardial infarction and a single , discrete , & gt ; 70 %
stenosis in the proximal right , left circumflex or left anterior descending coronary artery ( Group 1 ) and in 55 consecutive
patients ( 46
men ; mean age 58 + /- 9 years with
chronic stable angina and multiple , diffuse , & gt ; 70 % stenoses localized both in the right and left coronary arteries ( Group 2 ) . -
pubmed
Ocular ischemic syndrome in a
child with
moyamoya disease and
neurofibromatosis . -
pubmed
Patients with
moyamoya disease may be particularly susceptible to the development of
ocular ischemia due to the associated
carotid occlusion . -
pubmed
A 19 - month - old
boy presented with
neurofibromatosis and signs of
ocular ischemia . -
pubmed
Comparison of three intensive programs for chronic
low back pain patients : a prospective , randomized , observer - blinded study with one - year follow - up . -
pubmed
In a randomized , blinded study , we compared the outcome from a full - time functional restoration program with the outcome from shorter active rehabilitation programs for
patients with chronic , disabling
low back pain . -
pubmed
The study initially included 132
patients , randomized into one of three treatment programs : ( 1 ) an intensive 3 - week multidisciplinary program ; ( 2 ) active physical training and back school ; or ( 3 ) psychological
pain management and active physical training . -
pubmed
The effects of cage density on pullet live performance and blood indices of stress were evaluated in two commercial
White Leghorn strains housed at 38 , 32 , 26 , and 20 birds per cage from Day 1 to 6 wk of age , and 19 , 16 , 13 , and 10 birds per cage from 6 to 18 wk . -
pubmed
Doppler estimation of left ventricular filling pressures in
patients with
hypertrophic cardiomyopathy . -
pubmed
METHODS AND RESULTS : Thirty - five
HCM patients ( 52+/-15 years ) underwent LV catheterization simultaneously with 2 - dimensional and Doppler echocardiography . -
pubmed
PreA pressure estimation with these 2 methods was tested prospectively in 17 additional
HCM patients with good results ( E velocity / flow propagation velocity , r=0.76 ; E / Ea , r=0.82 ) . -
pubmed
CONCLUSIONS : LV filling pressures can be estimated with reasonable accuracy in
HCM patients by measuring E velocity / flow propagation velocity or E / Ea . -
pubmed
Smoking and therapeutic response to
clozapine in
patients with
schizophrenia . -
pubmed
BACKGROUND : Of
patients with
schizophrenia , 70 to 80 % smoke . -
pubmed
Nicotine corrects certain information processing and cognitive
psychomotor deficits seen in many
patients with
schizophrenia . -
pubmed
METHODS : We assessed psychopathology and smoking in 70
patients with
treatment refractory schizophrenia ( 55
smokers and 15
nonsmokers ) at baseline when they were receiving conventional antipsychotics and again after they were switched to
clozapine . -
pubmed
CONCLUSIONS : Certain
patients with
schizophrenia have contributing pathophysiologic mechanisms that respond favorably to either
nicotine or
clozapine . -
pubmed
BACKGROUND & amp ; AIMS :
Reinfection after treatment for
Helicobacter pylori is uncommon in adults . -
pubmed
SURGICAL REPAIR : The beneficial effect of myocardial revascularization on severe
ischemic cardiomyopathy , the relevance of mitral valve repair in
dilated cardiomyopathy , and the advantage of ventricular remodeling in
patients with
major ventricular dyskinesia has been clearly demonstrated . -
pubmed
ADAPTED TREATMENT : Optimal management of each
patient with advanced
heart failure requires an adequate treatment selected among a wide range of medical and/or surgical strategies . -
pubmed
Two female
patients ( age 56 and 62 years ) and one male ( age 44 years ) presented with recurrent
tracheobronchitis , a " difficult intubation " at the time of an emergency situation requiring tracheostomy . -
pubmed
Preventing the spread of
hepatitis B and
C viruses : where are germicides relevant ? -
pubmed
Hepatitis B virus ( HBV ) and hepatitis C virus (
HCV ) are the most prevalent bloodborne pathogens . -
pubmed
Both viruses remain difficult to work with in the laboratory , but closely related animal viruses ( such as the duck
HBV ) and the
bovine viral diarrhea virus show considerable promise as surrogates for
HBV and
HCV , respectively . -
pubmed
Prognostic value of left ventricular mass and its evolution during treatment in the Bordeaux cohort of
hypertensive patients . -
pubmed
Relationship between
Trypanosoma cruzi and
human chagasic megaesophagus : blood and tissue parasitism . -
pubmed
The persistence of
Trypanosoma cruzi in tissue and blood of 52
patients in the digestive form of chronic
Chagas disease was studied . -
pubmed
These data demonstrate that in the digestive form of
Chagas ' disease , particularly in cases of
megaesophagus ,
T. - pubmed
METHODS : In a prospective study of 107
patients affected by
brain tumors , we assessed
PE clinically and the rate of dilated vessels histologically . -
pubmed
RESULTS : 6.5 % of the
patients had an important
erythema and 18.5 % had slight and/or localized
PE . -
pubmed
CONCLUSION : in the case of
Streptococcus pneumoniae sepsis , a systematic search for Howell - Jolly bodies on blood smears and ultrasound examination of the abdomen for the presence of
asplenia should be mandatory to detect isolated
congenital asplenia . -
pubmed
All three
patients needed urgent surgical intervention with further laparotomies due to recurrent
ulceration ,
perforation and
fistula formation in addition to intensive supportive measures such as inotropes and total parenteral nutrition . -
pubmed
PURPOSE : To measure the blood flow velocities in feeder vessels of
patients with
choroidal neovascularization (
CNV ) secondary to age - related
macular degeneration . -
pubmed
METHODS : We examined the early images of
indocyanine green videoangiography ( v - ICGA ) in 29
patients ( 29 eyes ) with
CNV , in whom feeder vessels could be identified by v - ICGA . -
pubmed
Results were as follows : 1)The peripheral blood examinations revealed that 52.0 % of the examined have
parasitemia , of which 95.3 % was
P. - pubmed
Neither P.
malaria nor
P. - pubmed
Lack of effect of
amino acids on the
growth retardation due to unheated
soybeans . -
pubmed
[ The treatment of
Proteus infections of the urinary tract with
Lactobacillus acidolphus ] . -
pubmed
Effect of
diethylstilbestrol - induced
tumorigenesis on the secretory activity of the
rat anterior pituitary gland . -
pubmed
Resistance to
infection in burned
patients . -
pubmed
[ Features of the clinical picture and secretory function of the stomach in
patients with
peptic ulcer and their relation to various localizations of
ulcers ] . -
pubmed
Effects of
pyruvate administration on
infarct volume and
neurological deficits following permanent focal
cerebral ischemia in
rats . -
pubmed
The purpose of this study was to assess the neuroprotective effect and the neurological outcome after
pyruvate administration in a model of
ischemic stroke induced by permanent
middle cerebral artery occlusion (
pMCAO ) in
rats . -
pubmed
Patients with
beta - catenin - negative serous
carcinomas had a poorer overall survival than
patients with
beta - catenin - positive serous
carcinomas ( p = 0.013 ) . -
pubmed
MATERIAL AND METHODS : 29
patients with
Hodgkin ' s disease (
HD ) referred for baseline
FDG PET imaging before treatment and without evidence of bone marrow ( BM ) involvement were included in the study . -
pubmed
PATIENTS AND METHODS : We retrospectively reviewed all 11
patients ( 12 renal units ) treated with the combined approach of HoLEP and an upper - tract endourologic procedure for
stone disease . -
pubmed
Fourteen and 18 mm lesion gaps were created in a
rat sciatic nerve lesion model . -
pubmed
Bioassay (
P388 lymphocytic leukemia cell line and
human cancer cell lines ) guided separation of an extract prepared from the previously chemically uninvestigated
Texas grasshopper Brachystola magna led to isolation of the
cancer cell growth inhibitory
pancratistatin ( 1 ) ,
narciclasine ( 2 ) , and
ungeremine ( 3 ) . -
pubmed
A combination of
atrioventricular block and
sinoatrial block in a
horse . -
pubmed
Resistance based on slow - rusting genes has proven to be a useful strategy to develop
wheat cultivars with durable resistance to
rust diseases in wheat . -
pubmed
Validity and reproducibility of a new diagnostic motor performance test in
children with suspected
myopathy . -
pubmed
Fifteen functional items were used to measure muscle strength and muscle endurance in 68
patients ( 47
males , 21 females ; mean age 7y 8mo , SD 2y 2mo ; range 4 to 11y ) , who had been referred to our specialist centre in the past 3 years on suspicion of
myopathy . -
pubmed
The motor performance test can improve diagnostic procedure in
children suspected of having
myopathy . -
pubmed
Effects of
intrauterine infection on the function of the corpora lutea formed after first postpartum ovulations in dairy
cows . -
pubmed
This study was carried out to determine the relationship between postpartum
intrauterine infections , endocrine patterns and the function of corpora lutea formed following the first postpartum ovulations in dairy
cows . -
pubmed
The occurrence of moderate to heavy bacterial growth patterns and the repeated isolations of the similar organisms during postpartum suggests the persistence of
uterine infections in SC
cows . -
pubmed
Increases in PGFM concentrations prior to luteolysis in SC
cows were associated with moderate to heavy
infection . -
pubmed
The first outbreak of
acute diarrhea due to a pandemic
strain of
Vibrio parahaemolyticus O3 : K6 in Kolkata , India . -
pubmed
Patient characteristics including etiology of
end stage renal disease , presenting symptoms , serum
creatinine and postoperative followup were documented . -
pubmed
RESULTS : All 20
patients presented after assessment for a febrile
urinary tract infection , and 35 % had concurrent
lower urinary tract dysfunction . -
pubmed
Patients with
lower urinary tract dysfunction presented significantly earlier and had a higher postoperative serum
creatinine than those without
lower urinary tract dysfunction ( 1.1 vs 1.7 years , p = 0.048 ) . -
pubmed
Seven of 16
patients underwent followup voiding cystourethrogram , with 5 demonstrating resolution and 2 , both with
lower urinary tract dysfunction , exhibiting persistent
vesicoureteral reflux . -
pubmed
At a mean followup of 3.6 years 25 % of
patients experienced recurrent
pyelonephritis , while 75 % were asymptomatic . -
pubmed
One instance of
anastomotic stricture occurred in a
patient with
lower urinary tract dysfunction . -
pubmed
Patients with
lower urinary tract dysfunction are likely to present earlier after transplantation than those without
lower urinary tract dysfunction , and may have an increased risk of persistent
vesicoureteral reflux and
renal damage despite surgical correction . -
pubmed
Phase II trial of dose - dense
doxorubicin plus
gemcitabine followed by
paclitaxel plus
carboplatin in
patients with advanced
urothelial carcinoma and
impaired renal function . -
pubmed
BACKGROUND :
Cisplatin - based therapy is standard in
patients with advanced
urothelial carcinoma but a large proportion are ineligible due to
renal impairment . -
pubmed
METHODS :
Patients with advanced
urothelial carcinoma who were ineligible for
cisplatin were eligible based on at least 1 of the following : 1 ) serum
creatinine & gt;1.5 mg / dL ; 2 )
creatinine clearance of & gt;30 mL / min/1.73 m(2 ) and & lt;60 mL / min/1.73 m(2 ) ; and/or 3 ) prior nephrectomy . -
pubmed
Myelosuppression was the major
toxicity , with 28 % of
patients experiencing grade 3 - 4
neutropenia ; there were only 2 ( 8 % ) episodes of
febrile neutropenia . -
pubmed
Grade & gt ; or = 3 nonhematologic
toxicities were infrequent with the exception of grade & gt ; or = 3
thrombotic episodes in 4 ( 16 % )
patients . -
pubmed
CONCLUSIONS : Dose - dense sequential chemotherapy is tolerable and active in
patients with
urothelial carcinoma and
renal impairment . -
pubmed
Prolonged disease - free survival is achievable in a subset of
patients with primary unresectable disease or lymph - node only
metastases treated with
carboplatin - based therapy + /- surgical consolidation . -
pubmed
Randomized trials are needed to define the optimal regimen in
patients with advanced
urothelial carcinoma and
renal impairment . -
pubmed
Vascular complications of
supracondylar humeral fractures in
children . -
pubmed
The purpose of this study was to analyze the vascular complications of 24
children with
supracondylar humeral fractures treated in two affiliated hospitals and to propose a management plan . -
pubmed
BACKGROUND : Upon initial repair , most
patients with anomalous origin of the left coronary artery from the pulmonary artery (
ALCAPA ) present with severely
impaired ventricular function and
mitral regurgitation . -
pubmed
At final follow - up , 95.5 % of the
patients presented with a LVEF greater than 0.50 , and 84.1 % with a
mitral regurgitation less than grade 2 . -
pubmed
CONCLUSIONS : In the majority of
patients with
ALCAPA , both ventricular function and
mitral valve regurgitation normalize over time . -
pubmed
[ Efficacy of injectable
carbapenems for
respiratory infections caused by
Streptococcus pneumoniae and
Haemophilus influenzae with Monte Carlo simulation ] . -
pubmed
Streptococcus pneumoniae and
Haemophilus influenzae are two major pathogens for
respiratory tract infections , and those
infections might cause
critically ill patients . -
pubmed
, while for immunocompromised hosts or
infections by
penicillin - resistant
Streptococcus pneumoniae ( PRSP ) ,
PAPM / BP , 500 mg , b.i.d . -
pubmed
As for the
infections caused by
H. - pubmed
In vitro
fluoroquinolone susceptibility of
Pseudomonas aeruginosa isolates from
dogs with
ulcerative keratitis . -
pubmed
OBJECTIVE : To determine the in vitro
fluoroquinolone susceptibility profiles of
Pseudomonas aeruginosa isolates from
dogs with
ulcerative keratitis . -
pubmed
aeruginosa isolates from
dogs with
ulcerative keratitis were collected during a 3 - year period . -
pubmed
aeruginosa - associated
ulcerative keratitis in
dogs . -
pubmed
aeruginosa isolates collected from
dogs with
ulcerative keratitis in this study , the likelihood of susceptibility to the
fluoroquinolones evaluated was high . -
pubmed
We report a case in which a
patient presented with severe right lower
abdominal pain associated with
nausea and
vomiting 3 days after termination of pregnancy . -
pubmed
The infants during the first four months of life had the lowest risk for
Plasmodium falciparum ,
R malariae and
P. - pubmed
Because of the relative rarity of the disease -
MCL represents 6 % of
non - Hodgkin lymphoma - an obvious effort is needed to enroll
patients on clinical trials . -
pubmed
Effects of
thalidomide in a
mouse model of
cerulein - induced acute
pancreatitis . -
pubmed
The aim of the present study was to assess the effects of
thalidomide in a
murine model of necrotizing acute
pancreatitis . -
pubmed
Necrotizing acute
pancreatitis was induced in
mice by intraperitoneal injection of
cerulein ( hourly , x5 , 50 microg / kg ) ; in another group of animals ,
thalidomide was administered ( 200 mg / kg orally ) at 1 h after first
cerulein injection . -
pubmed
After 24 h , biochemical , histological , and immunohistochemical evidences of acute
pancreatitis developed in all
cerulein - treated
mice . -
pubmed
Therefore ,
thalidomide treatment attenuates the development of acute
pancreatitis caused by cerulein in
mice . -
pubmed
Little is known about the effect of dietary
carbohydrate , glycaemic index ( GI ) and glycaemic load ( GL ) on the risk of the
metabolic syndrome , especially in populations with
white rice as the staple food . -
pubmed
METHODS : Several clinical trials and large - scale epidemiological studies have evaluated the efficacy and tolerability of
sertindole in
patients with
schizophrenia . -
pubmed
[ Value of transrectal FNA in the diagnosis of
prostate cancer in elderly
patients ] . -
pubmed
OBJECTIVES : To identify if there is a group elderly
patients with clinical suspicion of
prostate cancer in which pathological confirmation may be unnecessary , and if prostatic transrectal fine needle aspiration ( FNA ) may be a useful diagnostic tool for old
patients . -
pubmed
RESULTS : In 35
patients ( 48.6 % ) cytological diagnosis was positive for
prostatic adenocarcinoma , whereas in 37 cytology was negative for
cancer . -
pubmed
When histological confirmation of
prostatic carcinoma is required in elderly
patients , transrectal prostatic FNA is a valid alternative to transrectal biopsy , due to its excellent tolerance and low complication rate . -
pubmed
METHODS : Two hundred
patients referred for outpatient
colorectal cancer screening were randomized to receive a single - dose of unlabeled
lubiprostone ( 24 microg ) or placebo prior to a split - dose
PEG - E bowel preparation without dietary restriction . -
pubmed
Patients enrolled in the
lubiprostone treatment arm rated the overall experience as more tolerable ( P 0.003 ) and complained of less
abdominal bloating ( P 0.049 ) . -
pubmed
A 37 - year - old
man was admitted with
cough and
fever . -
pubmed
Etiology of
goiter in
man ; new concepts . -
pubmed
[ Lipid peroxidation and antiradical defense in
patients after endosurgical
cholelithiasis ] . -
pubmed
We designed a prospective randomized trial of the two - incision THA versus the mini - posterior technique to determine whether
patients having two - incision THA , when compared with
patients having mini - posterior THA , had evidence of less
muscle damage as reflected by changes in hip muscle strength after surgery , a less antalgic gait as reflected by changes in the single - leg stance time and walking velocity , and better hip function as reflected by changes in the hip moments during level walking and stair climbing as assessed by comprehensive gait analysis testing . -
pubmed
We found no evidence that patients who had two - incision THA had less
muscle damage , less
antalgic gait , or better gait kinematics than
patients who had mini - posterior THA . -
pubmed
[ Results of low - vision rehabilitation in
vision impaired patients ] . -
pubmed
We report on
low vision rehabilitation in 100
vision impaired patients . -
pubmed
METHODS :
Low vision rehabilitation was performed in 100 consecutive
patients ( 61 %
AMD , 23 %
diabetic retinopathy , 16 % other diseases ) . -
pubmed
RESULTS : In 62
patients with
low vision fitted with a system for the far distance we reached an increase of the visual acuity of more than one line in 95 % . -
pubmed
[ '
Rheumatoid arthritis ' in a Surinamese
man :
leprosy ] . -
pubmed
Rheumatoid arthritis was diagnosed in a 65 - year - old
man from Suriname , on the basis of clinical and radiological findings . -
pubmed
Left ventricular diastolic mechanical dyssynchrony and associated clinical outcomes in
children with
dilated cardiomyopathy . -
pubmed
METHODS AND RESULTS : We calculated a diastolic and systolic dyssynchrony index ( standard deviation of time to peak tissue early diastolic / systolic velocity in 12 left ventricular segments ) in 33
children with
DCM and 46 control subjects . -
pubmed
A threshold to diagnose diastolic dyssynchrony was determined , and cardiac function and clinical outcomes were compared between
DCM patients with and without diastolic dyssynchrony . -
pubmed
The diastolic dyssynchrony index was significantly higher in
children with
DCM than in control subjects ( 28.1+/-18.1 versus 9.1+/-3.8 ms , P<0.0001 ) . -
pubmed
Patients who died or underwent transplantation had greater diastolic dyssynchrony ( diastolic dyssynchrony index 37.9+/-20.5 versus 22.1+/-13.8 ms , P=0.01 ) , and the rate of transplant - free survival appeared to be worse for
DCM patients with
diastolic dyssynchrony than for
patients with synchronous
DCM ( hazard ratio 2.98 , P=0.11 ; hazard ratio adjusted for disease duration 2.95 , P=0.17 ) . -
pubmed
CONCLUSIONS : Left ventricular diastolic mechanical dyssynchrony is common in pediatric
DCM , especially in
patients who subsequently experience transplantation or
death , and may be associated with a decreased length of transplantation - free survival . -
pubmed
Open reduction and internal fixation compared to closed reduction and external fixation in distal radial
fractures : a randomized study of 50
patients . -
pubmed
METHODS : 50
patients with an unstable or
comminute distal radius fracture were randomized to either closed reduction and bridging external fixation , or open reduction and internal fixation using the TriMed system . -
pubmed
5
patients in the external fixation group were reoperated due to
malunion , as compared to 1 in the internal fixation group . -
pubmed
Insight in modulation of
inflammation in response to
diclofenac intervention : a
human intervention study . -
pubmed
BACKGROUND : Chronic systemic low - grade
inflammation in obese
subjects is associated with health complications including
cardiovascular diseases ,
insulin resistance and
diabetes . -
pubmed
METHODS : To address this limitation , we used an integrative omics approach to characterize modulation of
inflammation in
overweight men during an intervention with the non - steroidal anti - inflammatory drug
diclofenac . -
pubmed
To assess the effectiveness of
deformity correction and safety of the two major corrective spinal surgical procedures , 35
patients , aged 14 - 47 years , were placed into two groups according to procedures performed . -
pubmed
What is the significance of solitary
bony abnormalities on bone scintigrams of
children with
malignancy ? -
pubmed
This investigation was undertaken to evaluate the significance of solitary
bony abnormalities on bone scintigrams of
children with known or suspected
malignancy . -
pubmed
A total of 215 bone scans were performed in 183
children in order to look for possible
metastasis over a 10 - year period . -
pubmed
Here , we examined the effect of diet - induced
maternal obesity on hippocampal development and function in the
mouse offspring . -
pubmed
Radiotherapy in the treatment of
patients with unresectable
extrahepatic cholangiocarcinoma . -
pubmed
We analyzed the role of definitive chemoradiotherapy for
patients with nonmetastatic , locally advanced
extrahepatic cholangiocarcinoma treated at a single institution . -
pubmed
METHODS AND MATERIALS : This retrospective analysis included 37
patients who underwent external beam radiation therapy ( EBRT ) with concurrent chemotherapy and/or brachytherapy ( BT ) for locally advanced extrahepatic
cholangiocarcinoma . -
pubmed
Two
patients were alive without evidence of
recurrence at the time of analysis . -
pubmed
Two
patients lived beyond 5 years without evidence of
recurrence . -
pubmed
Age , gender ,
tumor location ( proximal vs. distal ) , histologic differentiation , EBRT dose ( & lt;= or & gt;50 Gy ) , EBRT planning method ( two - dimensional vs. three - dimensional ) , and chemotherapy were not associated with
patient outcomes . -
pubmed
CONCLUSIONS :
Patients with locally advanced
extrahepatic cholangiocarcinoma have poor survival . -
pubmed
The majority of
patients treated with EBRT had local control at the time of
death , suggesting that symptoms due to the local
tumor effect might be effectively controlled with radiation therapy , and EBRT is an important element of treatment . -
pubmed
Patients with
stress incontinence or urgency ,
local irritation ,
infection , distal
stenosis or a
neoplastic process have very similar symptoms . -
pubmed
The
Clone 13 ( Cl13 ) strain of lymphocytic choriomeningitis virus is widely studied as a model of
chronic systemic viral infection . -
pubmed
OBJECTIVES : The purpose of this analysis was to characterize the progression of
coronary atherosclerosis in
patients with concomitant
peripheral arterial disease (
PAD ) . -
pubmed
The impact of concomitant
PAD on
coronary atherosclerosis progression in
patients with
coronary artery disease has not been well established . -
pubmed
METHODS : The burden and progression of
coronary atherosclerosis was investigated in 3,479
patients with
coronary artery disease with ( n = 216 ) and without ( n = 3,263 ) concomitant
PAD who participated in 7 clinical trials that employed serial intravascular ultrasound imaging . -
pubmed
RESULTS :
Patients with
PAD had a greater percent
atheroma volume ( 40.4 + - 9.2 % vs. 38.5 + - 9.1 % , p = 0.002 ) and percentage of images containing
calcium ( 35.1 + - 26.2 % vs. 29.6 + - 24.2 % , p = 0.002 ) , in association with smaller lumen volume ( 275.7 + - 101.6 mm(3 ) vs. 301.4 + - 110.3 mm(3 ) , p & lt ; 0.001 ) and vessel wall volume ( 467.7 + - 166.8 mm(3 ) vs. 492.9 + - 169.8 mm(3 ) , p = 0.01 ) . -
pubmed
On serial evaluation ,
patients with
PAD demonstrated greater progression of percent
atheroma volume ( +0.58 + - 0.38 vs. +0.23 + - 0.3 % , p = 0.009 ) and total
atheroma volume ( -0.17 + - 2.69 mm(3 ) vs. -2.05 + - 2.15 mm(3 ) , p = 0.03 ) and experienced more cardiovascular events ( 26.3 % vs. 19.8 % , p = 0.03 ) . -
pubmed
CONCLUSIONS :
Patients with concomitant
PAD harbor more extensive and calcified
coronary atherosclerosis ,
constrictive arterial remodeling , and greater
disease progression . -
pubmed
METHODS : This was a multicentre , randomized open - label study in which 418
patients with mild to moderate
AKs were randomized into two treatment groups . -
pubmed
In all , 180
patients with dorsal or plantar
diabetic foot ulcers ( unhealed for & gt;=1 month ) were randomized to receive Hyalograft-3D autograft first and then Laserskin autograft after 2 weeks ( n = 90 ; treatment group ) or nonadherent paraffin gauze ( n = 90 ; control group ) . -
pubmed
We analyzed treatment and outcomes of
patients undergoing multimodal endoscopic treatment of early
esophageal neoplasia at our institution . -
pubmed
METHODS : Records of
patients undergoing endoscopic treatment for
esophageal low - grade intraepithelial neoplasia (
LGIN , n = 11 ) ,
high - grade intraepithelial neoplasia (
HGIN , n = 24 ) , or T1N0M0
neoplasia ( n = 10 ) , presenting between 2007 and 2009 , were reviewed . -
pubmed
Neoplasia and intestinal
metaplasia were eradicated in 87.2 % and 56.4 % of
patients , respectively , while 15.4 % developed metachronous
neoplasia . -
pubmed
A minority of treated
patients developed recurrent
neoplasia , which is usually amenable to further endoscopic therapy . -
pubmed
Finally new research on
Cu -
Se supplementation is necessary to better understand the risk of the
animals to suffer from
Se deficiency . -
pubmed
BACKGROUND :
Dengue is the most important
human viral disease transmitted by arthropod vectors . -
pubmed
Establishment of primary
mouse lung adenocarcinoma cell culture . -
pubmed
In this study , 2 out of 5
primary lung adenocarcinoma cultures derived from
DNA repair - deficient mice were established and characterised using electron microscopy and immunostaining . -
pubmed
All
patients had surgical repair of a postinfarction
ventricular septal rupture . -
pubmed
RESULTS : Surgery for postinfarction
ventricular septal rupture was carried out on 59
patients . -
pubmed
In 54 % of
patients , the
ventricular septal rupture was anterior , and 75 % had concomitant coronary artery bypass grafting . -
pubmed
MATERIAL AND METHODS : All
patients with
sinonasal malignancies ( n = 177 ) treated between 1996 and 2010 at the Department of Head and Neck Surgery , University of Bonn , Germany were analyzed retrospectively . -
pubmed
Data on age , gender and incidence were available for all
patients but other demographic data , treatment regimes and outcome were only analyzed for
carcinomas . -
pubmed
Interestingly , 64 % of
patients with sinonasal
carcinoma presented with locally advanced disease ( T3 - 4 ) but only 15 % displayed corresponding regional lymph node
metastases . -
pubmed
Infection is generally
bacterial in nature . -
pubmed
In high - risk
prostate cancer patients , there is accumulating evidence that either dose escalation to the prostate or hypofractionation may improve outcome . -
pubmed
Although investigational , this review discusses the challenging idea of WPRT in the context of hypofractionation for
patients with high - risk
prostate cancer . -
pubmed
The use of endoscopic retrograde cholangiopancreatography for treating benign
biliary strictures has become the standard of practice , with surgery and percutaneous therapy reserved for selected
patients . -
pubmed
OBJECTIVE : To explore the proliferation inhibition and apoptosis effects of polysaccharides extracts from
Hedyotis diffusa ( PEHD ) on
multiple myeloma ( MM ) cell line RPMI 8226 cells in vitro , so as to provide experimental theory for the clinical application in the treatment of
MM . -
pubmed
Quality of sleep in
patients with
Parkinson ' s disease . -
pubmed
The most important aim of this study was to evaluate the sleep quality in
patients with
PD . -
pubmed
METHODS : This case - control study was performed on
patients with
PD referred to the Neurology Clinic of our teaching hospital in 2011 . -
pubmed
Thirty - four
patients with
PD and 34 healthy
people as control group were enrolled in this study . -
pubmed
Sleep quality of
patients and control was evaluated by
Parkinson ' s disease sleep scale ( PDSS ) questionnaire . -
pubmed
RESULTS : The mean total PDSS score in
patient group was 55.29 ( SD = 26.92 ) indicating moderate to severe
sleep disturbances whereas , the mean total score in control group was 20.34 ( SD = 10.65 ) . -
pubmed
CONCLUSIONS : Our study demonstrated that
patients with
PD experienced poorer nocturnal sleep quality than the control group . -
pubmed
Hydatid disease is a
parasitic infestation caused by the tapeworm
Echinococcus granulosus . -
pubmed
We successfully treated a 55 - year - old
woman with primary
peritoneal hydatidosis . -
pubmed
The
patient was managed by a combination of preoperative and postoperative antihelminthic therapy along with laparotomy ,
cyst deroofing , toileting and omentoplasty . -
pubmed
A multicenter case - case control study for risk factors and outcomes of extensively drug - resistant
Acinetobacter baumannii bacteremia . -
pubmed
Case group 1 was defined as having
infection due to XDR
A. - pubmed
baumannii , and case group 2 was defined as having
infection due to non - XDR
A. - pubmed
Pitt
bacteremia score ( adjusted odds ratio [ aOR ] , 2.570 [ 95 % confidence interval ( CI ) , 1.528 - 4.322 ] ) , central venous catheters ( CVCs ; aOR , 12.644 [ 95 % CI , 2.143 - 74.620 ] ) , use of
carbapenems ( aOR , 54.391 [ 95 % CI , 3.869 - 764.674 ] ) , and
piperacillin - tazobactam ( aOR , 55.035 [ 95 % CI , 4.803 - 630.613 ] ) were independently associated with XDR
A. - pubmed
In case group 2 , Pitt
bacteremia score ( aOR , 1.667 [ 95 % CI , 1.265 - 2.196 ] ) and third - generation
cephalosporins ( aOR , 2.965 [ 95 % CI , 1.224 - 7.182 ] ) were independently associated with non - XDR
A. - pubmed
Survivors received more active empirical therapy ( 16.7 % vs 9.6 % ; P = .157 ) , had fewer cases of XDR
bacteremia ( 45.8 % vs 52.6 % ; P = .452 ) , and received higher median definitive
polymyxin B doses ( 840,000 units vs 700,000 units ; P = .339 ) CONCLUSIONS : Use of CVC and broad spectrum antibiotics were unique risk factors of XDR
A. - pubmed
The " Seroquel " Outcomes Study ( SOS ): Efficacy and tolerability of
quetiapine in a long - term , naturalistic study of
patients with
schizophrenia . -
pubmed
The " Seroquel " Outcomes Study ( SOS ) aimed to assess the efficacy and tolerability of
quetiapine in
patients with
schizophrenia in the clinical practice setting . -
pubmed
A 6 - month , non - comparative , open - label study in
adults with
schizophrenia in a standard care setting in Spain . -
pubmed
Quetiapine was found to improve symptoms of
schizophrenia , as indicated by a significant decrease in BPRS scores , and was well tolerated by
patients in clinical practice . -
pubmed
The aims of this prospective randomized study were to investigate the incidence of
trigger finger in
patient groups undergoing transverse carpal ligament releasing ( TCL ) or TCL together with distal forearm fascia releasing and to identify other factors that may have an effect of these conditions . -
pubmed
CASE PRESENTATION : The proband is a 49 - year - old
man who underwent cerebral MRI in his thirties for persistent
haeadache and
tingling in his left arm and leg and was diagnosed with
multiple supratentorial cavernous angiomas . -
pubmed
Almost 21 % of
patients were bothered by an
impaired gustatory ability and 50.5 % of
patients were affected by their
loss of olfaction . -
pubmed
Frequent nasal discharge was reported in 20 % , frequent
sneezing in 58.1 % , and
nasal itching in 33.3 % of the laryngectomized
patients . -
pubmed
INTRODUCTION :
Skin and soft tissue infections involve microbial invasion of the skin and underlying soft tissues and are estimated to affect 7 - 10 % of hospitalized
patients worldwide . -
pubmed
Patients in India , aged from 1 to 65 years old , suffering from mild to moderate
bacterial skin infections including
impetigo , secondarily
infected wounds ,
folliculitis , infected
atopic dermatitis , and
furunculosis were randomly allocated to three treatment groups within the studies . -
pubmed
All English language articles reporting on a minimum of five
patients<=18 - years old , treated with flexible ureteroscopy and lasertripsy for
stone disease were included . -
pubmed
MATERIALS AND METHODS : Fourteen healthy
volunteers were subjected to transient normobaric
hypoxia in an air - conditioned chamber simulating an
oxygen concentration of a height of up to 5500 meters . -
pubmed
Long - term clinical outcome of
patients who failed catheter ablation of
atrial fibrillation . -
pubmed
AIMS : Left atrial ablation fails to prevent symptomatic
recurrences of
atrial fibrillation (
AF ) in 20 - 30 % of
patients up to 3 years of follow - up despite multiple procedures . -
pubmed
METHODS AND RESULTS : In this multicentre study , 218 ( 34 % ) of 631 consecutive
patients , who had undergone AF catheter ablation in the years 2001 - 11 for drug - refractory symptomatic
AF , had symptomatic
AF recurrences after 1.5 + - 0.6 procedures . -
pubmed
At a mean of 5.1 + - 2.6 years since their last ablation , 82 ( 38 % )
patients improved , 103 ( 47 % ) remained unchanged and 33 ( 15 % ) worsened , but only 17 ( 8 % ) had such a severe impairment of their quality of life as to require atrioventricular junction ablation and pacing ( # 13 ) or cardiac surgery ( # 4 ) ; 22 ( 10 % )
patients had had adverse clinical events (
death in five ,
heart failure in five ,
stroke and transient
ischaemic cerebral attack in four , severe
haemorrhage in four , pacemaker or implantable cardioverter - defibrillator implantation in seven ) and 98 ( 45 % )
patients had developed permanent
AF . -
pubmed
Compared with
patients without permanent
AF , fewer
patients with permanent
AF improved ( 3 % vs. 66 % , P = 0.001 ) and more got worse ( 28 % vs. 5 % , P = 0.001 ) . -
pubmed
CONCLUSION : More than 5 years after a failed
AF ablation , a small minority of
patients had such an impaired quality of life as to require non - pharmacological interventions . -
pubmed
Permanent
AF was more common in
patients who had left
atrial enlargement , history of persistent
AF , longer follow - up , and had performed a single ablation procedure , thus hypothesizing that reablation could reduce the chronicization of
arrhythmia . -
pubmed
CASE PRESENTATION : We report a case of 24 - year - old
man with idiopathic
ventricular tachycardia from a single focus in the supravalvular left ventricular outflow tract with two extremely divergent breakouts observed during the ablation procedure . -
pubmed
Effective global
tuberculosis control is hindered by the need for prolonged chemotherapy which leads to poor
patient compliance . -
pubmed
Normal BALB / c
mice were infected with DeltahspX or the wild type ( WT )
strain . -
pubmed
Three weeks after
infection , the
mice were treated with
rifampicin ,
isoniazid and
pyrazinamide for 14 weeks followed by 8 weeks of
hydrocortisone . -
pubmed
Effects of pomegranate and
pomegranate -
apple blend juices on the growth characteristics of
Alicyclobacillus acidoterrestris DSM 3922 type
strain vegetative cells and spores . -
pubmed
This study was designed to evaluate the prevalence and severity of
CAD with the use of MDCT angiography in asymptomatic KT
recipients . -
pubmed
METHODS : From September 2011 to November 2013 , MDCT angiography was performed on 90 renal transplant
recipients who had no pre - transplantation
CAD history and stabilized post - transplantation renal function for 6 - 18 months . -
pubmed
The relevance of this relationship was then confirmed in
human primary
tumours . -
pubmed
The purpose of the present study was to compare
heparin administration and activated clotted times ( ACTs ) for
patients undergoing CA for
AF treated with interrupted
apixaban before the procedure with
patients on uninterrupted
warfarin . -
pubmed
METHODS : Consecutive
patients undergoing CA for
AF treated with interrupted
apixaban or uninterrupted
warfarin were prospectively enrolled . -
pubmed
Seventeen
SLE patients ( 13 females , four
males ) died at a median follow - up of 48 months . -
pubmed
METHODS : We conducted a quasi - experimental study among
overweight and obese
school children enrolled in 7th and 8th grades in Sousse , Tunisia with two groups , intervention and control . -
pubmed
The 1 - year intervention was based on promoting healthy eating and physical activity through a collective intervention for all recruited
children and an individual intervention only for
obese children who require intensive managing . -
pubmed
Visceral fat percentage was used as a measure of the
animals '
weight gain during the trial . -
pubmed
INTRODUCTION : In
patients with normal estimated renal function before robot - assisted partial nephrectomy ( RPN ) , there is still a risk for de Novo
chronic kidney disease (
CKD ) . -
pubmed
We assessed the role of dipstick
spot proteinuria in risk stratifying
patients for
CKD progression . -
pubmed
Proteinuric patients were compared with the remainder of the cohort with parametric comparisons for continuous and chi - squared analysis for categoric variables . -
pubmed
RESULTS : We found 269
patients with eGFR & gt;60 preoperatively , of whom 57 ( 21 % ) had
proteinuria preoperatively . -
pubmed
CONCLUSIONS :
Patients with
proteinuria preoperatively , despite a normal
eGFR , likely have intrinsic
medicorenal disease . -
pubmed
MATERIALS AND METHODS : Forty
patients diagnosed with persistent
AR or
non - allergic rhinitis referred to Shafa Medical Center affiliated to Kerman University of Medical Sciences were included in this study and were randomly allocated to the intervention or control groups . -
pubmed
Patients received an injection of 80 units
BTA ( Dysport , Ipsen Ltd Company , UK ) at a concentration of 200 mU / ml in normal saline on four
spots in each side of the nose and were followed for 12 weeks . -
pubmed
CONCLUSION : Submucoperichondrial
BTA injection can be considered an effective therapeutic option in
patients with persistent
AR and
idiopathic rhinitis . -
pubmed
MATERIALS AND METHODS : A total of 305 prospective
melanoma patients undergoing sentinel node biopsy were compared with 616 retrospective control
patients with clinically localized
melanoma whom have not undergone sentinel node biopsy . -
pubmed
RESULTS : Overall , there were no differences in
relapse - free survival or
cancer - specific survival between sentinel node biopsy
patients and control
patients . -
pubmed
Male sentinel node biopsy
patients had significantly higher
relapse - free survival ( P = 0.021 ) and
cancer - specific survival ( P = 0.024 ) than control
patients . -
pubmed
Cancer - specific survival rates at 5 years were 87.8 % in sentinel node biopsy
patients and 85.2 % in controls overall with 88.3 % in male sentinel node biopsy
patients and 80.6 % in male controls and 87.3 % in female sentinel node biopsy
patients and 89.8 % in female controls . -
pubmed
CONCLUSION : Sentinel node biopsy did not improve survival in
melanoma patients overall . -
pubmed
While
females had no differences in survival ,
males had significantly improved
relapse - free survival and
cancer - specific survival following sentinel node biopsy . -
pubmed
[
Arteriovenous malformations of the brain : personal experience with 121
patients treated with microsurgery ] . -
pubmed
OBJECTIVES : This study was designed to indicate whether different fractions from
Artemisia biennis hydroethanolic extract could provide cytoprotection against oxidative stress and apoptosis induced by
doxorubicin (
DOX ) in
rat pheochromocytoma cell line (
PC12 ) . -
pubmed
For evaluation of the effect of fractions ( A - G ) on
DOX - induced
cytotoxicity ,
PC12 cells were pretreated for 24 hr with the
A. - pubmed
Protective efficacy of
folic acid and
vitamin B12 against
nicotine - induced
toxicity in pancreatic islets of the
rat . -
pubmed
In this study , male
Wister rats were treated with
nicotine ( 3 mg / kg body weight/ day ) with or without supplementation of
folic acid ( 36 mug / kg
body weight / day ) or
vitamin B12 ( 0.63 mug / kg
body weight / day ) alone or in combination . -
pubmed
The results revealed that
nicotine induced
prediabetes condition with subsequent damage to pancreatic islets in
rats . -
pubmed
These results suggest that supplementation of
folic acid and
vitamin B12 in combination may be a possible strategy of detoxification against
nicotine - induced
toxicity in pancreatic islets of the
rat . -
pubmed
Here we report such a
tumor , measuring 3 cm in diameter , found in the parotid gland of an 81 - year - old
man . -
pubmed
Association of
cardiac cachexia and
atrial fibrillation in
heart failure patients . -
pubmed
BACKGROUND :
Cachexia is a common complication in
patients with advanced
heart failure (
HF ) associated with inflammatory response activation . -
pubmed
OBJECTIVES : Evaluate the association of
cardiac cachexia and
atrial fibrillation in
heart failure patients . -
pubmed
Subjects with
congenital heart disease ,
cancer ,
HIV , drug use and other causes than
HF were excluded . -
pubmed
During follow - up 47.8 % of subjects developed
CC and 17.27 %
AF , this was significantly more frequent in
cachectic patients CC ( 23 % vs 12.11 % , OR : 2.17 , 95 % CI : 1.19 - 4.01 , p=0.006 ) . -
pubmed
INTRODUCTION :
Coinfection with certain members of the Flaviviridae , such as
Dengue Virus (
DV ) ,
West Nile Virus (
WNV )
Yellow Fever Virus (
YFV ) and most importantly ,
GBV - C have been documented to reduce
HIV-1 viral load in vivo . -
pubmed
Numerous studies strongly support the notion that persistent
coinfection with non - pathogenic virus prolongs survival in
HIV-1 infected individuals . -
pubmed
CONCLUSION : We hypothesize that a recombinant
GBV - C - based vector can be constructed which expresses several beneficial genetic motifs of the Flaviviridae without causing any side effects while stimulating a wide array of beneficial miRNAs that can more efficiently prevent
HIV-1 infection . -
pubmed
RESULTS : All 71
patients reported being incapable of any voluntary reaction during the
shock of the application time . -
pubmed
We assessed
ampicillin (
ABPC ) concentrations of liver , kidney and skin at a 2 - day withdrawal period in ten male and ten female
White Leghorn chickens fed the diet containing
ABPC (
ABPC medicated feed 40 mg / kg
body weight / day ) for a week . -
pubmed
CASE SUMMARY : One case of duodenal
IFP was described and the literature is reviewed with emphasis on the clinical and pathological features of
IFP in
children . -
pubmed
A case of an
IFP in the duodenum of a 13 - year - old
girl , who presented with
abdominal pain ,
weight loss ,
vomiting , and
constipation . -
pubmed
CONCLUSION : To our best of our knowledge , this is the fourth report of
IFP in
adolescents , the first in a female 's duodenum . -
pubmed
More of the
M.tb proteome needs to be screened to identify proteins that induce strong antibody responses in
LTBI . -
pubmed
BACKGROUND AND PURPOSE : Objective ambulatory activity during daily living has not been characterized for
people with
Parkinson disease prior to initiation of dopaminergic medication . -
pubmed
Our goal was to characterize ambulatory activity based on average daily step count and examine determinants of step count in nonexercising
people with de novo
Parkinson disease . -
pubmed
The pharmacodynamics of low and standard doses of
ticagrelor in
patients with
end stage renal disease on hemodialysis . -
pubmed
BACKGROUND :
Patients with
end - stage renal disease (
ESRD ) on maintenance hemodialysis ( HD ) respond poorly to
clopidogrel . -
pubmed
We assessed the utility of low - dose
ticagrelor in
ESRD patients on maintenance HD . -
pubmed
CONCLUSIONS : Low - dose
ticagrelor afforded greater platelet inhibition than did
clopidogrel in
ESRD patients on HD . -
pubmed
All nomograms had higher calibration and much better net benefit than the scenarios in predicting
patients with or without different zones
prostate cancer . -
pubmed
BACKGROUND : In Brazil , studies on animals and
humans in mainland areas have shown that most
strains of
Toxoplasma gondii are pathogenic to
mice and exhibit great genetic variability . -
pubmed
gondii
strains from one
cat and three
rats on Fernando de Noronha Island . -
pubmed
Prospective Study of Cetuximab ,
Carboplatin , and Radiation Therapy for
Patients With Locally Advanced
Head and Neck Squamous Cell Cancer Unfit for
Cisplatin . -
pubmed
PURPOSE : To report on the outcomes of a novel treatment regimen for
patients with locally advanced
head and neck squamous cell carcinoma who were fit for curative treatment but not fit for
cisplatin . -
pubmed
METHODS AND MATERIALS : Single - arm phase 1/2 study of previously untreated
patients with biopsy - proven
SCC of the oropharynx , larynx , or hypopharynx . -
pubmed
Propranolol treatment lowers blood pressure , reduces vascular inflammatory markers and improves endothelial function in
obese mice . -
pubmed
Therefore , autonomic blockade was demonstrated to reverse
hypertension ,
endothelial dysfunction and IR in obese
individuals . -
pubmed
Body weight ,
systolic blood pressure (
SBP ) , plasma biochemical parameters and aortic endothelial function were analyzed in
mice fed standard diet ( control group ) or a high fat diet ( HFD ) that were treated with vehicle ( water ) or
propranolol ( 10mg / kg / day ) for 8weeks . -
pubmed
A 55 - year - old
man with
syncopal episodes was found to have
sinus bradycardia at a rate of 37 beats / min , an episode of nonsustained
ventricular tachycardia , and
left ventricular noncompaction cardiomyopathy . -
pubmed
After pretreatment , the
rats were subjected to 60 min of right
middle cerebral artery occlusion (
MCAO ) . -
pubmed
RESULTS : Administration of
CBD ( 100 and 200 ng /
rat ) caused a significant reduction in
infarction ,
brain oedema , and BBB permeability compared with the vehicle - received group . -
pubmed
Natural course of
tonsillectomy pain : A prospective
patient cohort study . -
pubmed
After undergoing tonsillectomy ,
patients scored their
pain using the visual analogue scale three times daily ( morning , midday , and evening ) for 2 weeks . -
pubmed
Postoperative
pain was less in
children and
adolescents ( & lt;=18years old ) than in adults ( & gt;18 years old ) ( EV=-0.81 , 95 % CI=-1.56 to -0.08 , P=0.031 ) . -
pubmed
A
patient was diagnosed with a ruptured 1.2 - cm subcortical
AVM after presenting with
intracerebral hemorrhage in the right frontal lobe and anterior basal ganglia . -
pubmed
Echocardiographic Evaluation of the Right Atrial Area Index in
Dogs with
Pulmonary Hypertension . -
pubmed
BACKGROUND : Right atrial area ( RAA ) is a prognostic factor in
human patients with
pulmonary arterial hypertension (
PAH ) . -
pubmed
Reference intervals for
RAA have been described in healthy
dogs . -
pubmed
ANIMALS : A total of 119 client - owned
dogs , 48
dogs with
PAH and 71 control
dogs . -
pubmed
RESULTS : The RAA index was higher in
dogs with moderate
PAH ( 13.3 cm2 /m2 ; range , 3.4 - 24.7 cm2 /m2 ) and severe
PAH ( 12.1 cm2 /m2 ; range , 5.4 - 21.8 cm2 /m2 ) than in those with mild
PAH ( 6.7 cm2 /m2 ; range , 4.8 - 10.7 cm2 /m2 ) or in controls ( 7.3 cm2 /m2 ; range , 4.2 - 10.2 cm2 /m2 ; P & lt ; 0.001 ) . -
pubmed
The RAA index was higher ( P & lt ; 0.0001 ) in
dogs with R -
CHF ( 17.5 cm2 /m2 ; range , 12.7 - 24.7 cm2 /m2 ) compared to those without R -
CHF ( 7.6 cm2 /m2 ; range , 4.4 - 19.4 cm2 /m2 ) . -
pubmed
In
dogs with
PAH , severity of
tricuspid regurgitation (
TR ) was the only independent predictor of RAA index based on multivariate analysis ( P & lt ; 0.02 ) . -
pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : The RAA index can be used to evaluate right atrial size in
dogs and may be more effective than TRPG in predicting R -
CHF in
dogs with
PAH . -
pubmed
The severity of
TR is the main determinant of the RAA index in
dogs with
PAH . -
pubmed
OBJECTIVES / HYPOTHESIS : To develop a prediction model that can accurately predict the chance of success following revision stapes surgery in
patients with recurrent or persistent
otosclerosis at 2- to 6 - months follow - up and to validate this model internally . -
pubmed
MATERIAL AND METHOD : A retrospective study was performed of all
patients who had a history of
melanoma and underwent EBUS - TBNA to assess hilar or mediastinal
lymphadenopathy for the presence of
metastatic melanoma . -
pubmed
RESULTS : Eight
patients had been diagnosed with
malignant melanoma in the past ( mean 54.4 months , range 18 to 115 months ) while in the other three this
tumor was primarily diagnosed in the staging phase . -
pubmed
Altered functional connectivity between sub - regions in the thalamus and cortex in
schizophrenia patients measured by resting state BOLD fMRI at 7T. -
pubmed
Design , Setting , and Participants : This multicenter cohort study conducted manual audits of medical records of 375
patients who underwent 1 of 3 urologic procedures ( transurethral resection of
bladder tumor [ TURBT ] , transurethral resection of the prostate [ TURP ] , and ureteroscopy [ URS ] ) at 5 Veterans Health Administration facilities from January 1 , 2016 , to June 30 , 2017 . -
pubmed
Ten or eleven days later , the
rats began behavioral testing that included 10 sessions of tone -
shock pairings . -
pubmed
Early progression of
Krabbe disease in
patients with symptom onset between 0 and 5 months . -
pubmed
The purpose of this prospective study was to describe the natural progression of early onset
Krabbe disease in a large cohort of
patients . -
pubmed
METHODS :
Patients with early onset
Krabbe disease were prospectively evaluated between 1999 and 2018 . -
pubmed
Results of nerve conduction studies showed that 100 % of
patients developed
peripheral neuropathy by 6 months of age . -
pubmed
Seizure Susceptibility Correlates with
Brain Injury in Male
Mice Treated with
Hypothermia after Neonatal
Hypoxia -
Ischemia . -
pubmed
Neonatal
seizures and subsequent
chronic epilepsy are frequent in this
patient population and current treatments are partially effective . -
pubmed
Thus , there are sex - specific consequences of neonatal
HI on
flurothyl seizure susceptibility in a
murine neonatal
HI model . -
pubmed
Effect of
Mizagliflozin on Postprandial Plasma
Glucose in
Patients With
Functional Constipation . -
pubmed
In this study , we intended to apply
melatonin in
melatonin - deficient
mice to ascertain whether
melatonin could reduce the incidence / severity of
scoliosis , and investigate the role of
melatonin on bone mineral density in
scoliosis . -
pubmed
All
volunteers breathed dry air for
vocal fold dehydration . -
pubmed
Results : Compounds 3a , 3o , 3s and 3 t , showed broad anti - kinetoplastid activity against all
species and
strains tested . -
pubmed
Patients receiving RRT had higher preoperative Charlson Comorbidity Index values ( median , 5 vs 4 ; P=.03 ) , Model for End - Stage
Liver Disease scores ( mean , 19.0 vs 14.5 ; P<.001 ) , right atrial pressure ( mean , 19.1 vs 13.4 mm Hg ; P<.001 ) , and estimated 24 - hour urine protein levels ( median , 357 vs 174 mg ; P<.001 ) and lower preoperative estimated
glomerular filtration rate ( eGFR ) ( median , 43 vs 57 mL / min ; P<.001 ) and measured
GFR using
125I - iothalamate clearance ( median , 33 vs 51 mL / min ; P=.001 ) than those who did not require RRT . -
pubmed
Approximately 40 % of
patients with
eGFR less than 45 mL / min/1.73 m2 and 24 - hour urine protein level greater than 400 mg required RRT vs 6 % with
eGFR greater than45 mL / min/1.73 m2 and without significant
proteinuria . -
pubmed
Candida glabrata is a problematic opportunistic pathogen that is associated with high mortality in
invasive infection , as well as both intrinsic and rapidly acquired antifungal resistance . -
pubmed
Efficacy of
povidone - iodine against accidental
tumor incision during nephron - sparing surgery : experimental study in
patients with
renal cell carcinoma . -
pubmed
Therefore , we compared ultrastructural indexes of angiogenic process and capillary remodelling by transmission electron microscopy in 9
COPD patients and 7
SHS after 6 weeks of individualized moderate - intensity endurance training . -
pubmed
We observed a capillary basement membrane thickening in
COPD patients only ( p = 0.008 ) and abnormal variations of endothelial nucleus density in response to exercise training in these
patients when compared to
SHS ( p = 0.042 ) . -
pubmed
COPD patients had significantly fewer occurrences of pericyte / endothelium interdigitations , a morphologic marker of capillary maturation , than SHS ( p = 0.014 ) , and significantly higher levels of F2 - IsoP ( p = 0.048 ) . -
pubmed
This study is the first to show abnormal capillary remodelling and to reveal impairments during the whole process of angiogenesis ( capillary creation and maturation ) in
COPD patients . -
pubmed
For the first time , we assess the biodistribution and
toxicity of unshelled CIS and partially
zinc - alloyed CISZ QDs in a
murine model . -
pubmed
Impact of
Sevoflurane Versus
Propofol Anesthesia on Post - Operative
Cognitive Dysfunction in Elderly
Cancer Patients : A Double - Blinded Randomized Controlled Trial . -
pubmed
We evaluated whether
sevoflurane - based anesthesia increased the incidence of
POCD and worsened prognosis compared to
propofol - based anesthesia in elderly
cancer patients . -
pubmed
Comparison of Experimental
Infection of Normal and Immunosuppressed Chickens with
Mycoplasma gallisepticum . -
pubmed
Four different models of
infection of
chickens with
Mycoplasma gallisepticum (
MG ) were evaluated . -
pubmed
Material and Methods : In this case - control study , 30
preeclampsia patients and 30 healthy pregnant
women as control group were selected and matched for maternal age , gestational age , and
BMI . -
pubmed
In a recent review , we have suggested a neuroinvasive potential of
severe acute respiratory syndrome coronavirus 2 (
SARS - CoV-2 ) and its possible role in the causation of acute
respiratory failure of
coronavirus disease 2019 ( COVID-19 ) patients ( J Med Viol doi : 10.1002 / jmv.25728 ) , based upon the clinical and experimental data available on the past
SARS - CoV-1 and the recent
SARS - CoV-2 pandemic . -
pubmed
In addition , we also discuss the peculiar manifestations of
respiratory failure in
COVID-19 patients and the possible involvement of nervous system . -
pubmed
RESULTS : The expression of miR-488 was reduced in OC , which was associated with poor clinical outcomes and prognosis in
OC patients . -
pubmed
However , there is a paucity of data regarding the safety and effectiveness of balloon aortic valvuloplasty ( BAV ) in
children with AVS with
LV dysfunction . -
pubmed
Therefore , the aim of this study was to evaluate outcomes to establish the safety and effectiveness of BAV in
children with
AVS and
LV dysfunction in improving LV function and survival . -
pubmed
Methods A total of 160 BAVs were performed from 2004 to 2017 ; of these , 41 ( 25.6 % )
patients had
LV dysfunction . -
pubmed
Results
Children who had undergone BAV for
AVS and
LV dysfunction within the age range of six to 192 months showed a significant reduction in peak - to - peak pressure gradient ( PPG ) from 73.5 + - 30 mmHg to 26.7 + - 6.7 mmHg and improvement in LVEF from 32.8 + - 11 % to 54.3 + - 12.7 % after 24 hours . -
pubmed
Four
patients died , all of whom had severe
LV dysfunction - one died during the procedure and three died within six to 20 hours after successful BAV . -
pubmed
Conclusion
Patients with
AVS who develop
LV dysfunction deteriorate and die soon without treatment . -
pubmed
Clinical characteristics and oncologic outcomes in
patients with preoperative clinical T3 and T4
colon cancer who were staged as pathologic T3 . -
pubmed
It is necessary to address the shortcomings of pathologic exams in the matter of the understaging of T4
colon cancer , and to reinforce the treatment for local control in
patients with cT4
colon cancer . -
pubmed
The
patient did not experience
recurrence during the follow - up period . -
pubmed
OBJECTIVES : The aim of this study was to analyze mitral annulus ( MA ) dynamics using cardiac magnetic resonance ( CMR ) in
patients with degenerative
mitral insufficiency who underwent mitral valve repair ( MVR ) . -
pubmed
METHODS : Mitral valve imaging was performed by CMR in twenty - nine
patients with degenerative
mitral insufficiency who underwent MVR between July 2014 and August 2016 , with quadrangular resection of the posterior leaflet without ring annuloplasty . -
pubmed
Still , in
PCOS women , treatment with
metformin or
TZDs not only modulates the lipid metabolism , but also improves the ovulation . -
pubmed
Also ,
metformin with lifestyle interventions has positive effects on the metabolic and reproductive features of
PCOS patients . -
pubmed
The compound is evaluated both in impregnated
cotton wound dressings and in a gel formulation against
skin infections caused by
Staphylococcus aureus and
methicillin resistant
S. - pubmed
The present work demonstrates that AMC-109 displays a significantly higher antibacterial activity with up to a seven - log reduction in
bacterial loads compared to current clinical standard therapy ; Altargo cream ( 1 %
retapamulin ) and
Fucidin cream ( 2 %
fusidic acid ) in the in vivo
wound models . -
pubmed
The
lecithins of the primary
hepatoma induced by
3 '- methyl-4 - dimethylaminoazobenzene (
DAB ) and host liver of
rat were isolated , and the individual molecular species were estimated quantitatively by combined thin - layer and gaschromatographic analysis and specific enzymic hydrolysis . -
pubmed
Immunofluorescence staining showed
infection with respiratory syncytial virus (
RSV ) . -
pubmed
[
Acute pericarditis caused by
Rickettsia conori ] . -
pubmed
A new case report of acute
pericarditis due to
Rickettsia conori , the seventh to be published in the French literature , highlights the following facts:--the widespread distribution of fievre
boutonneuse , which is to be found in a wide strip around the Meditteranean basin;--the mechanism by which the pericardium is affected , which is probably auto - immune;--the criteria for the biological diagnosis of the
Rickettsial diseases;--above all , the neccessity for prolonged antibiotic therapy , however apparently benign the disease may have seemed . -
pubmed
We report an unusual case of
hypoglycaemia , in which a pregnant
woman with a Rh - negative problem and random blood
glucose levels of less than 10 mg/100 ml was found to have no clinical symptoms of
hypoglycaemia . -
pubmed
[ Glycogenolysis indices in the skeletal muscles of
rats with experimental
rickets ] . -
pubmed
Content of glycogen and
lactic acid was decreased in sceletal muscles of growing male
rats during the acute periof of experimental
rachitis . -
pubmed
Thirty - two
patients with clinical evidence of
anterior horn cell dysfunction are descirbed . -
pubmed
During the period of follow - up ( 1 to 5 years ) none of the
patients without
bulbar dysfunction initially developed such symptoms . -
pubmed
In all these
patients electromyographic evidence of
anterior horn cell disease was confirmed . -
pubmed
Conspicuous absence of pyramidal signs , elevated plasma
citrate , normal plasma
pyruvate values and the extremely slow progression suggest that this group of
patients are different from other varieties of
anterior horn cell dysfunction previously described . -
pubmed
[ The efficiency of surgical treatment of
patients with
malignant tumors of nasal cavity and paranasal
sinuses ] . -
pubmed
In the years 1966 - 80 , 96
patients with
malignant tumors of nasal cavity and paranasal
sinuses were surgically treated in the Department of Otolaryngology , Medical University in Cracow . -
pubmed
[
Human cytomegalovirus -- biology and
infection ] . -
pubmed
These data confirm that
women with
ovarian carcinoma produce an abnormal amount of
steroids . -
pubmed
Thus the clinical application of
steroids as
tumor markers in unselected
patients is limited . -
pubmed
In 2
patients the
cyst showed little change . -
pubmed
This article deals with state of the art reconstruction and rehabilitation of the
head and neck cancer patient who requires mandibular resection . -
pubmed
II : Inhibitory effect of
N , N , N - trimethylsphingosine on metastatic potential of
murine B16 melanoma cell line through blocking of
tumor cell - dependent
platelet aggregation . -
pubmed
We recently observed that
N , N , N - trimethylsphingosine (
TMS ) and
N , N - dimethylsphingosine (
DMS ) , but not
sphingosine (
SPN ) , had an inhibitory effect ( via blocking of transmembrane signaling ) on the growth of various
human tumor cell lines in vitro as well as in vivo in
nu / nu mice ( K. Endo et al . -
pubmed
Some authors have demonstrated that
magnesium therapy reduces the mortality in
AMI patients . -
pubmed
After the
patient 's diagnosis of
adrenoleukodystrophy was confirmed ,
long - chain fatty acid levels were obtained on his 5 - year - old brother and his mother . -
pubmed
Anaesthesia in
malignant hyperthermia - susceptible
patients without
dantrolene prophylaxis : a report of 30 cases . -
pubmed
We conclude that the prophylactic use of
dantrolene is not necessary in
patients suspected to be prone to
MH if triggering agents are avoided and the
patients are closely monitored . -
pubmed
A prospective study of 0.1 sec and 0.2 sec duration argon laser trabeculoplasty was undertaken in 33
patients with chronic simple
glaucoma . -
pubmed
Psychogenic seizures in
children and
adolescents : outcome after diagnosis by ictal video and electroencephalographic recording . -
pubmed
Psychogenic seizures in 21 nonepileptic
children and
adolescents , aged 8 to 18 ( mean 14.5 ) years , were recorded by means of video recording and electroencephalography . -
pubmed
Fifteen
patients had
psychogenic seizures spontaneously during recording , and six had
seizures in response to suggestion and intravenous saline injection . -
pubmed
A case of
septicaemia due to
Aeromonas hydrophila . -
pubmed
A case of
Aeromonas hydrophila septicaemia is reported , arising from the use of leeches in an attempt to salvage a replanted arm . -
pubmed
The myeloid body - formation is not directly correlated to
human nephrotoxicity . -
pubmed
Experimental induction of
malignant lymphomas can be achieved in the
cottontop tamarin by inoculation with
Epstein - Barr ( EB ) virus . -
pubmed
This system provides an animal model for assessing the efficacy of vaccine protection against the virus which is intended to reduce the incidence of
human tumours associated with
EB virus infection , namely endemic
Burkitt ' s lymphoma and
undifferentiated nasopharyngeal carcinoma . -
pubmed
Demonstration in live
chickens of the carrier state in
infectious laryngotracheitis . -
pubmed
Two separate groups of nine - week - old specific pathogen free
cockerels maintained in isolation were infected with a field
strain of infectious laryngotracheitis (
ILT ) virus , either by intratracheal or combined intranasal and supraconjunctival inoculation . -
pubmed
[ Characteristics of cellular and humoral immunity in gynecological
patients with severe forms of suppurative -
septic diseases ] . -
pubmed
Fourteen
men with a mean duration of
infertility greater than 3 years who had significant sperm immobilizing or sperm - agglutinating antibodies were studied . -
pubmed
Using
rats with
tumor transplanted into the subcutaneous tissue ,
tumor resections done with either an ordinary scalpel or a laser scalpel were compared from the viewpoints of
tumor recurrence and survival time . -
pubmed
The concentration of
HpD in the
tumor tissue of
WKA rats with DAB
hepatic tumor was twice that in liver tissue . -
pubmed
Thus ,
AVP contributes modestly to the elevation of arterial pressure caused mainly by neurogenic mechanisms in
SAD rats during the early postoperative period . -
pubmed
Tc-99 m RBCs should be the initial test in
patients with
GI bleeding . -
pubmed
Some characteristics of the
cyclophosphamide - induced immunopotentiating cells in the spleen of
mice bearing a large
MOPC-315 tumor . -
pubmed
Riboflavin nutritional status of
rats suffering from essential
fatty acid deficiency . -
pubmed
Acute
toxicity in
rats and
mice exposed to
hydrogen chloride gas and aerosols . -
pubmed
[ Incidence , pathogenesis , and prevention of
grass tetany in
cattle . -
pubmed
Acute and convalescent sera from
human pneumonia patients from whom
M. - pubmed
Lymph production during staphylococcic B
enterotoxemia - induced
shock in
monkeys . -
pubmed
[ Aspects of
liver damage in
human and experimental
poisoning with
tri - orthocresylphosphate ] . -
pubmed
AMINO antagonizes the head twitch reaction induced by
5 - hydroxytryptophan in
mice and
tryptamine convulsions in
rats . -
pubmed
The
hyperthermia induced by
fenfluramine ( in
rats at a high ambient temperature ) as well as the stimulation of the hind limb flexor reflex in spinal
rats , induced by
fenfluramine or
LSD , are also inhibited . -
pubmed
AMINO antagonizes the
5 - HT - induced
increase in blood pressure in pithed
rats . -
pubmed
This is particularly odd considering that five of the seven
women suffered serious
gastrointestinal hemorrhage during one or more of their pregnancies . -
pubmed
The five articles are reviewed , basic information regarding
PXE is given , a case history is recorded , and the possibility that pregnancy favors the development of these complications in
patients with
PXE is discussed . -
pubmed
Enzyme - linked immunosorbent assay ( ELISA ) as a diagnostic tool for Guatemalan
onchocerciasis using a
bovine filaria (
Onchocerca gutturosa ) antigen and blood samples collected on filter paper . -
pubmed
They involve the quality of life for
cancer patients , after initial curative treatments . -
pubmed
A study of rheological determinants ( plasma viscosity , whole - blood viscosity , and erythrocyte deformability ) was made in 24 matched pairs of
patients with
homozygous sickle cell disease , with and without homozygous
alpha - thalassaemia 2 . -
pubmed
The effect of
halothane anaesthesia on the foetal responses to acute
haemorrhage was studied in chronically prepared
ewes . -
pubmed
Glycogen in pancreatic islets of
steroid diabetic rats . -
pubmed
In the islets of the
rat pancreas ,
steroid diabetes induced by
triamcinolon - acetonid leads to degranulation of the B cells and glycogen infiltration . -
pubmed
A
patient with an
acute abdomen during pregnancy is reported . -
pubmed
Patients aged 18 to 65 years with histologically proven
breast cancer treated by surgery and without distant
metastases were eligible for the study . -
pubmed
One of 10 entered
patients , 1 was not evaluated due to missing data on
hematologic toxicity . -
pubmed
None of the affected
individuals have cardiac or ocular manifestations of the
Marfan syndrome . -
pubmed
When cells of
HL 60 , as a
human lymphoma , were cultured with
thionsulfolipid , 61 % of the cell growth was inhibited at the concentration of 200 micrograms / ml . -
pubmed
Sensation was normal in the
scars of the donor areas in all but three
patients . -
pubmed
METHODS : In a retrospective study , we assessed the clinical presentation of 23
patients with one or more
NCSE episodes , their medical history , EEG , and antiepileptic drug ( AED ) treatment . -
pubmed
RESULTS : There was considerable overlap in clinical features of
patients with complex partial
SE (
CPSE ) and generalized nonconvulsive
SE (
GNSE ) . -
pubmed
The structure of the O - antigenic polysaccharide from a
strain of
Aeromonas caviae , isolated from the stools of a patient with
diarrhoea , has been investigated . -
pubmed
DHEA acetate ( 0.35 mol / kg body wt ) was injected intraperitoneally to one - half of the
animals while the others were injected with
corn oil vehicle . -
pubmed
Pulmonary thromboembolism (
PTE ) was diagnosed in 22
patients at Saga Medical School between 1981 and 1994 . -
pubmed
When enhanced CT was done during acute severe
respiratory failure in 3
patients , pulmonary artery filling defects were found in all . -
pubmed
CASE :
Sarcoidosis of the genital tract occurred in a
woman with a 16 - year history of
pulmonary sarcoidosis . -
pubmed
STUDY DESIGN : Neurodevelopmental tests including the Stanford - Binet Intelligence ( IQ ) scale and the Developmental Test of Visual Motor Integration ( VMI ) were administered to 32
children ( 26 months to 16 years of age ) with
complex single ventricle . -
pubmed
Children who had deep hypothermic
circulatory arrest during a prior Norwood procedure tended to have a lower IQ score . -
pubmed
Secondary abnormality of
carnitine biosynthesis results from
carnitine reabsorptional system defect in
juvenile visceral steatosis mice . -
pubmed
We characterized the
L - carnitine transport system which is defective in the kidney of
juvenile visceral steatosis ( JVS )
mice by using kidney slices and
carnitine - related compounds , and evaluated the influence of the transport defect on the biosynthetic pathway of
carnitine . -
pubmed
It has been suggested that the presence of
subdural hematoma in
patients with severe
head injury is associated with
elevated intracranial pressure and higher mortality . -
pubmed
Twenty - four hours after the injection , of the
hematoma in the subdural space in
rats produced an extensive zone of underlying
ischemic damage but
silicone oil did not . -
pubmed
Progressive
ataxia ,
myoclonic epilepsy and
cerebellar apoptosis in
cystatin B - deficient mice . -
pubmed
HIV /
AIDS is a serious problem in sub - Saharan Africa . -
pubmed
The adult
mammalian central nervous system ( CNS ) fails to regenerate its axons following
injury . -
pubmed
In unselected cell lines and probably also in
human cancer , multiple mechanisms are redundantly present to defend the
organism from the insults of drugs . -
pubmed
[ Pharmacokinetics of
fusidic acid in
patients with seriously infected
burns ] . -
pubmed
The pharmacokinetics of
fusidic acid (
FA ) were studied in 10 infected severe
burns patients ( 35 + /- 5 yrs , 81 + /- 17 kg ) i.e. -
pubmed
In the absence of
impaired liver function , this is attributable to the known increase in hepatic clearances in
burns patients and , to a certain extent , to the existence of translesional extra - hepatic clearance , which could contribute to the success of treatment . -
pubmed
Effect of a new starch - free bread on metabolic control in
NIDDM patients . -
pubmed
All
patients had well established non
insulin - dependent diabetes mellitus . -
pubmed
CONCLUSIONS : Substitution of ordinary bread with starch - free bread at breakfast causes significant improvements in blood
glucose levels in
NIDDM patients on both a short and long term basis . -
pubmed
Abnormalities of skeletal muscles are frequently observed in
patients with
congestive heart failure . -
pubmed
OBJECTIVES : We sought to determine whether
abciximab therapy at the time of percutaneous coronary intervention ( PCI ) would favorably affect one - year mortality in
patients with
diabetes . -
pubmed
The one - year mortality rate for
patients with a clinical diagnosis of
diabetes mellitus was compared with the rate for nondiabetic
patients treated with either
abciximab or placebo . -
pubmed
RESULTS : In the 1,462
diabetic patients ,
abciximab decreased the mortality from 4.5 % to 2.5 % , p = 0.031 , and in the 5,072 nondiabetic
patients , from 2.6 % to 1.9 % , p = 0.099 . -
pubmed
In
patients with the clinical
syndrome of
insulin resistance -- defined as
diabetes ,
hypertension , and
obesity -- mortality was reduced by
abciximab treatment from 5.1 % to 2.3 % , p = 0.044 . -
pubmed
CONCLUSIONS : Abciximab decreases the mortality of
diabetic patients to the level of placebo - treated nondiabetic
patients . -
pubmed
This beneficial effect is noteworthy in those
diabetic patients who are also
hypertensive and
obese and in
diabetics undergoing multivessel intervention . -
pubmed
Besides its potential role in reducing repeat intervention for stented
diabetic patients ,
abciximab therapy should be strongly considered in
diabetic patients undergoing PCI to improve their survival . -
pubmed
HIV /
AIDS case histories : diagnostic problems . -
pubmed
Two inoculation routes were used to compare the ability of MT78 and
PA68 to colonize the respiratory tract and to induce
colibacillosis in
chickens . -
pubmed
Irrespective to the inoculation route , MT78 and
PA68 showed similar abilities to induce macroscopic lesions in
chickens , to provoke
bacteremia , and to colonize the internal organs . -
pubmed
METHODS :
Hearing loss developed in the
patient at age 4 ,
blindness at age 48 , and
dystonia at age 57 . -
pubmed
We find that 36 % of
AD patients have elevated perceptual thresholds for left / right outward radial optic flow discrimination . -
pubmed
This reveals global pattern perceptual deficits that affect most
AD patients ( 85 % ) and some normal elderly subjects ( 21 % ) . -
pubmed
Pancreas after kidney transplants in posturemic
patients with
type I diabetes mellitus . -
pubmed
Pancreas after previous kidney ( PAK ) transplants are an attractive option for
type 1 diabetic patients because of the short waiting time and use of living kidney donors . -
pubmed
Effects of acute
sleep restriction on behavior , sustained attention , and response inhibition in
children . -
pubmed
OBJECTIVE : To assess the influence of race on the treatment and survival of
patients with distal
esophageal cancer . -
pubmed
RESULTS : Black
patients with
esophageal adenocarcinoma were less likely to undergo surgery ( OR , 0.54 ; 95 % CI , 0.30 - 0.96 ) but had similar odds of undergoing chemotherapy and radiation therapy . -
pubmed
Black
patients with
squamous cell carcinoma (
SCC ) were less likely to undergo surgical resection ( OR , 0.45 ; 95 % CI , 0.29 - 0.70 ) , but were more likely to undergo radiation therapy ( OR , 1.72 ; 95 % CI , 1.21 - 2.47 ) and chemotherapy ( OR , 1.74 ; 95 % CI , 1.19 - 2.54 ) . -
pubmed
Mortality was increased for black
patients with
SCC ( adjusted risk ratio 1.33 ; 95 % CI , 1.10 - 1.61 ) but not
adenocarcinoma . -
pubmed
Ruling out a
neurological deficit in knock - out
mice , both
strains reacted similarly to novelty , to intraperitoneal saline , or to the administration of
scopolamine ( 1 mg / kg ) , an anti - muscarinic agent . -
pubmed
In conclusion , it was evidenced that more than 10 % of micromycete
strains developing on incorrectly - preserved fruit ,
berries and
vegetables , produce toxic secondary metabolites that pose a potential health hazard for people eating or handling the foodstuff . -
pubmed
Clinical and psychosocial outcome of
patients affected by
panic disorder with or without
agoraphobia : results from a naturalistic follow - up study . -
pubmed
OBJECTIVE : A clinical and psychosocial follow - up study of a cohort of 85
patients affected by
panic disorder (
PD ) with or without
agoraphobia was performed an average of 40 months after initial observation and following a mean duration of illness of 8 years . -
pubmed
METHODS : Eighty - five out of 130
patients affected by
PDs with or without
agoraphobia according to DSM - III R criteria , examined between 1990 and 1995 at an outpatient clinic were re - examined in 1997/1998 using the same standardized clinical evaluation performed on admission . -
pubmed
CONCLUSIONS : The findings of the study are suggestive of a
chronic illness with a significant impact on everyday quality of life of
patients . -
pubmed
Dermatologic and oral findings in a cohort of 47
patients with
Papillon - Lefevre syndrome . -
pubmed
In this group , 15 invasive lobular
carcinomas were identified in 12
patients . -
pubmed
CB interventions have been shown to reduce
pain and improve psychosocial functioning in
patients who have
chronic illnesses , particularly chronically painful
rheumatologic syndromes . -
pubmed
[ Sexual difference in
pancreatic diabetes in
rats castrated at birth ] . -
pubmed
It is widely accepted that this procedure is to be recommended only in
patients with early stage
tumours . -
pubmed
[
VITAMIN B-12 ABSORPTION IN
PATIENTS WITH
GASTRIC CANCER AND FOLLOWING GASTRIC RESECTION ] . -
pubmed
Galactorrhea - associated
granulosa cell tumor in a
child . -
pubmed
Granulosa cell tumor of the ovary is a rare form of
ovarian cancer in
children . -
pubmed
An 11 - year - old
girl was admitted with complaints of
galactorrhea and
abdominal mass . -
pubmed
The clinical , hormonal , and radiological findings and the therapy of
galactorrhea associated with
granulosa cell tumor in a
child are discussed . -
pubmed
Anne McLaren is one of the world 's foremost developmental biologists ; a leader in elucidating the principles of early
mammalian development whose research has underpinned advances in reproductive medicine and the treatment of
infertility . -
pubmed
Anaemia induced by
iron deficiency may cause a challenge concerns for pregnant
women , babies and adolescent , primarily . -
pubmed
This
Ewing sarcoma animal model will be a useful tool for dissecting the molecular pathogenesis of
Ewing sarcoma and provides rationale for the broader use of organ - specific progenitor cell populations for the study of
human sarcoma . -
pubmed
A total of 414 faecal specimens collected from
diarrhoeic dogs and tested positive to
CPV-2 were analysed by the MGB probe assays and by conventional methods ( haemagglutination inhibition with MAbs , PCR - RFLP and sequence analysis ) for prediction of the
CPV-2 antigen specificity , with an overall agreement of 100 % . -
pubmed
A 34 - year - old
man with
Darier - White disease : a case report and review of the literature . -
pubmed
We report a case of a
man with
Darier - White disease followed by a review of the current literature on the pathogenesis , clinical features , diagnosis , and treatment of this
cutaneous malady . -
pubmed
Outcome of short - term antiepileptic treatment in
patients with solitary
cerebral cysticercus granuloma . -
pubmed
A total of 206
subjects with new onset
seizures with
SCCG were randomized into two groups : group A ( 98
patients ) were treated for 6 months and group B ( 108
patients ) were treated for 2 years with
AED therapy . -
pubmed
RESULTS : Partial
seizures with or without secondary generalization has been found to be the commonest manifestation occurring in 80.6 % of
patients with
SCCG . -
pubmed
In
patients having residual
calcification , 42.2 % in group A and 21.7 % in group B had
recurrence of
seizures and the difference was statistically significant ( Z = 1.97 , P & lt ; 0.05 ) . -
pubmed
Higher
recurrence rate was observed in short - term therapy in
patients having
calcified lesions and may require long - term AED treatment . -
pubmed
In the present study , we evaluated the CBO changes induced by bypass blood flow in
patients with
MD and non - MD during the peri - operative periods employing optical spectroscopy . -
pubmed
Neutropenia developed in both groups inoculated with a
BVDV isolate . -
pubmed
Genetically modified
mice models for
Alzheimer ' s disease . -
pubmed
Transgenic
mice models for
Alzheimer ' s disease (
AD ) are essential to the understanding of disease pathophysiology , develop robust behavioral models and predict outcomes from pharmacological interventions . -
pubmed
Although
Staphylococcus epidermidis is the most common pathogen involved ,
infections with
Staphylococcus aureus lead to severe
peritoneal damage and are often associated with a dramatic loss of mesothelial cells . -
pubmed
However , even after prolonged
infection , a high percentage of
S. - pubmed
Cell
death induced by
S. - pubmed
In conclusion , our data indicate that mesothelial cell
death might represent a major mechanism of
S. - pubmed
MATERIAL AND METHODS : We retrospectively reviewed
patients with a positive urine culture with or without clinical symptoms of
urinary tract infection admitted to an intensive care unit . -
pubmed
RESULTS : The growth of microorganisms was determined in urine of 82 ( 3.9 % )
patients :
urinary tract infection in 64 ( 78 % ) and colonization in 18 ( 22 % ) patients . -
pubmed
In our opinion endovascular therapy is a good therapeutic option for chronic
mesenteric ischemia in high surgical risk
patients , specially when dealing with
stenotic injuries . -
pubmed
The clinical value of multilevel soft tissue release in the management of dynamic and static limb
deformities in
cerebral palsy children . -
pubmed
The present article attempts to define the clinical , functional and radiological indications for multilevel soft tissue release in the treatment of static and dynamic
deformities in
cerebral palsy children . -
pubmed
By restoring muscular balance , surgical treatment influences the presence and extent of dynamic and static joint
deformity in the
CP child and improves the child 's general condition . -
pubmed
PURPOSE : The primary objective of this study was to compare rates of
urinary tract and soft tissue infections in
critically ill burn patients before and following introduction of a Bowel Management System ( BMS ) . -
pubmed
Critically ill burn patients using a BMS were matched with similar patients managed before introduction of the device based on gender , total body surface area burned ,
burn location , ventilation days , and hospital length of stay . -
pubmed
Trisomies in
humans , such as
trisomy 21 , are due to the missegregation of one chromosome in the first meiotic division in the oocyte . -
pubmed
Failure to respond to the surface of
Plasmodium falciparum infected erythrocytes predicts susceptibility to clinical
malaria amongst African children . -
pubmed
METHODS : Between 2003 and 2006 , 26 consecutive
patients ( 7
cerebral palsy , 10
Duchenne muscular dystrophy , 5
spinal muscular atrophy and 4 others ) with
neuromuscular scoliosis underwent posterior pedicle screw fixation for the
deformity . -
pubmed
CONCLUSION : Results indicate that in
patients with
neuromuscular scoliosis , acceptable amounts of curve correction can be achieved and maintained with posterior - only pedicle screw instrumentation without anterior release procedure . -
pubmed
One - gram portions of
chicken frankfurters were inoculated with 0.5 log CFU of a single
strain ( ATCC 700408 ) of
Salmonella Typhimurium DT104 . -
pubmed
Spontaneous
ovarian hyper stimulation syndrome and
deep vein thrombosis in a non pregnant
woman : case report . -
pubmed
CASE : A 27 - year - old non pregnant
woman with bilateral ovarian masses who had underwent laparotomy for suspicion of
malignant tumor . -
pubmed
CONCLUSION : The incidence of
thromboembolism in
women with
OHSS is low and the typical finding is deep
venous thrombosis in the neck area . -
pubmed
Atlantic salmon smolts challenged intraperitoneally ( ip ) and by cohabitation with a highly virulent
strain of
infectious pancreatic necrosis virus showed strong activation of important immune genes in spleen , liver , head - kidney and gill measured by real - time quantitative PCR . -
pubmed
Two
boys with the clinical and radiographic picture of acute tropical
pyomyositis of the short external rotators of the hip were treated surgically followed by parenteral antibiotics ( Figure 1 ) . -
pubmed
Staphylococcus aureus is responsible for the
infection in & gt;75 % of the cases . -
pubmed
Five
patients ( 3.7 % ) discontinued AST at a median of 13 months ( range , 6 - 18 months ) because of
disease progression ( n = 1 ) ,
hot flashes ( n = 2 ) ,
fatigue ( n = 1 ) , and
impotence ( n = 1 ) . -
pubmed
After a median follow - up of 37.4 months ( range , 24 - 90 months ) , the highest Radiation Therapy Oncology Group - defined late
urinary toxicities were Grade 0 in 47.8 % , Grade 1 in 38.1 % , Grade 2 in 7.5 % , and Grade 3 in 6.7 % of
patients . -
pubmed
Maximal late gastrointestinal
toxicities were Grade 0 in 73.1 % , Grade 1 in 16.4 % , Grade 2 in 7.5 % , and Grade 3 in 2.9 % of
patients . -
pubmed
Heroin users are at high risk for
HIV infection , but little is known about
HIV risk in
oxycodone users . -
pubmed
Until recently , the optimal work - up of
patients with stable
coronary artery disease (
CAD ) was based on non - invasive functional tests . -
pubmed
Current indications for CCTA include symptomatic
patients with intermediate pre - test probability of
CAD with altered ECG ( LBBB , repolarization abnormalities ) rendering stress tests useless or patients unable to achieve sustained stress effort , and patients with indeterminate or uninterpretable results on ischemic work - up . -
pubmed
Alglucosidase alfa : Long term use in the treatment of
patients with
Pompe disease . -
pubmed
W - Swiss
mice 60 or more days old are more readily immunizable against
rabies virus infection than 20 day old or younger
mice ; this difference in immunizability with increasing age is most conspicuous when vaccination with virulent virus is followed by intracerebral test
infection and least apparent when vaccination with avirulent virus is followed by intramuscular test
infection . -
pubmed
MRI was collected in 32
AD patients , 24
MCI subjects and 18 healthy controls ( HC ) . -
pubmed
Nine out of 24
MCI subjects converted to
AD after an average follow - up interval of 2.5 years . -
pubmed
BACKGROUND :
Human clear cell renal cell carcinoma (
CRCC ) remains resistant to therapies . -
pubmed
METHOD : A total of 322
patients with acute
myocardial infarction participated in this study within 48 hours of hospital admission . -
pubmed
Patients completed the Brief Symptom Inventory to assess
anxiety level . -
pubmed
The administration of
metoprolol did not eliminate this relationship , perhaps because
patients did not receive a sufficient dose of
metoprolol to counter the effect of
anxiety . -
pubmed
We report our own experience of a male
patient with
bladder perforation after an early instillation of a single dose of
MMC . -
pubmed
Flash frozen lung samples removed from two
patients undergoing lung transplantation for severe
COPD ( n=4 ) were compared to similar samples from an unused donor lung ( n=2 ) that served as a control . -
pubmed
[ An elderly
man with known
heart failure admitted with
cardiogenic shock ] . -
pubmed
Intracranial meningioma in
children : different from adult forms ? -
pubmed
OBJECTIVE :
Intracranial meningiomas are very rare in
children , comprising only 0.4 to 4.1 % of pediatric
tumors and only 1.5 to 1.8 % to all
intracranial meningiomas . -
pubmed
PATIENT AND METHODS : We conducted a retrospective study from June 1983 to June 2007 ; during this period 521
patients underwent surgery for primary
meningioma at the Rabat Hospital , Department of Neurosurgery . -
pubmed
In one
patient a
neurofibromatosis was associated . -
pubmed
This inhibitory effect is
DENV dose dependent , requires
DENV replication , and takes place in
DENV - infected DCs as early as 2 h after
infection . -
pubmed
METHODS : We reviewed 45 electroencephalograms of
patients divided into two groups : those with benign childhood
epilepsy with centrotemporal spikes (
BCECTS ) and symptomatic
partial epilepsy (
SPE ) , following ILAE criteria ( 1989 ) . -
pubmed
RESULTS : There was a predominance of horizontal dipole between
patients with
BCECTS compared with
patients with
SPE ; however , this difference was not statistically significant . -
pubmed
The metastasectomy and timing of pulmonary
metastases on the outcome of
osteosarcoma patients . -
pubmed
METHODS : Data was obtained retrospectively on all consecutive
osteosarcoma patients from 1985 to 2005 in author 's institute . -
pubmed
In addition , the
patients presented with lung
metastases had a worse prognosis as compared with those without initial lung
metastases ( p = 0.0001 ) . -
pubmed
Patients who had late
metastases after complete chemotherapy had a better prognosis ; whereas those who had
metastases identified at the initial presentation predicted a poor prognosis . -
pubmed
Dengue is an acute emerging
infectious disease transmitted by
Aedes mosquitoes and has become a serious global public health problem . -
pubmed
We report the case of a 69 - year - old asymptomatic
woman who presented with the incidental diagnosis of a prominent ,
vascular , reddish tumor of the iris . -
pubmed
The objective of this study was to use optical coherence tomography to determine if a subset of
patients with
multiple sclerosis exhibit primary
retinal neuronopathy , in the absence of
retrograde degeneration of the retinal nerve fibre layer and to ascertain if such
patients may have any distinguishing clinical characteristics . -
pubmed
We identified 50
patients with
multiple sclerosis with predominantly macular thinning ( normal retinal nerve fibre - layer thickness with average macular thickness & lt ; 5th percentile ) , a previously undescribed optical coherence tomography defined phenotype in
multiple sclerosis , and compared them with 48
patients with
multiple sclerosis with normal optical coherence tomography findings , 48
patients with
multiple sclerosis with abnormal optical coherence tomography findings ( typical for
multiple sclerosis ) and 86 healthy controls . -
pubmed
Utilizing a novel retinal segmentation protocol , we found that those with predominant macular thinning had significant thinning of both the inner and outer nuclear layers , when compared with other
patients with
multiple sclerosis ( P & lt ; 0.001 for both ) , with relative sparing of the
ganglion cell layer . -
pubmed
Inner and outer nuclear layer thicknesses in
patients with non - macular thinning predominant
multiple sclerosis were not different from healthy controls . -
pubmed
Functional corroboration of
retinal dysfunction was provided through multi - focal electroretinography in a subset of such
patients . -
pubmed
These findings support the possibility of primary retinal pathology in a subset of
patients with
multiple sclerosis . -
pubmed
Multiple sclerosis - severity scores were also significantly increased in
patients with the macular thinning predominant phenotype , compared with those without this phenotype ( n = 96 , P=0.006 ) . -
pubmed
We have identified a unique subset of
patients with
multiple sclerosis in whom there appears to be disproportionate thinning of the inner and outer nuclear layers , which may be occurring as a primary process independent of optic nerve pathology . -
pubmed
Patients with inner and outer nuclear layer pathology have more rapid disability progression and thus retinal neuronal pathology may be a harbinger of a more aggressive form of
multiple sclerosis . -
pubmed
[ Hypothesis for the formation of
human unresponsiveness to
immunodeficiency virus ] . -
pubmed
Particular emphasis is laid on
human immunodeficiency virus (
HIV-1 ) , its origin theory , the time and site of its primary manifestations . -
pubmed
INTRODUCTION :
Hyperoxia has recently been reported as an independent risk factor for mortality in
patients resuscitated from
cardiac arrest . -
pubmed
We examined the independent relationship between
hyperoxia and outcomes in such
patients . -
pubmed
METHODS : We divided
patients resuscitated from nontraumatic
cardiac arrest from 125 intensive care units ( ICUs ) into three groups according to worst PaO2 level or alveolar - arterial
O2 gradient in the first 24 hours after admission . -
pubmed
RESULTS : Of 12,108 total
patients , 1,285 ( 10.6 % ) had
hyperoxia , 8,904 ( 73.5 % ) had
hypoxia / poor
O2 transfer , 1,919 ( 15.9 % ) had normoxia and 1,168 ( 9.7 % ) had isolated
hypoxemia ( PaO2 & lt ; 60 mmHg ) . -
pubmed
METHODS : Two hundred ninety - one
patients with
type 2 diabetes and significant
depressive symptoms ( Beck Depression Inventory scores & gt;= 14 ) were recruited from a community - based , university - based , and Veterans Affairs health care systems . -
pubmed
Intervention
patients had significantly greater increases in step counts ( mean difference , 1131 steps / d ; P=0.0002 ) and greater reductions in
depressive symptoms ( 58 % remitted at 12 mo vs. 39 % ; P=0.002 ) . -
pubmed
Environmental enrichment rescues postnatal neurogenesis defect in the male and female Ts65Dn
mouse model of
Down syndrome . -
pubmed
Impaired neurogenesis in the neocortex , hippocampus and cerebellum is believed to be the underlying cause of
learning and behavioral deficits in the Ts65Dn
mouse model of
DS . -
pubmed
Here , using the Ts65Dn
mouse model of
DS , we demonstrate that a combination of environmental enrichment and physical exercise starting in juvenile
mice ( postnatal day 18 ) markedly increases cell proliferation , neurogenesis and gliogenesis in the hippocampal dentate gyrus ( DG ) and the forebrain subventricular zone ( SVZ ) of both male and female
mice . -
pubmed
Long - term evaluation of safety and health - related quality of life in
women with heavy
menstrual bleeding treated with oral
tranexamic acid . -
pubmed
AIMS : A multicenter , long - term , open - label study was conducted to assess the safety and health - related quality of life ( HRQoL ) of an oral
tranexamic acid ( TA ) formulation in
women with
cyclic heavy menstrual bleeding (
HMB ) . -
pubmed
The most commonly reported TEAEs among
women in the intent - to - treat population ( n = 723 ) were
headache ,
menstrual discomfort and
back pain . -
pubmed
Thirty - nine
human breast cancer cell lines were also included in this study . -
pubmed
At 24 hours after administration , documented
erythema was seen around the injection site in a dose - dependent manner , particularly in all
adults with
MSU dose & gt;=200 mug . -
pubmed
Among four
Hepatitis C Virus ( HCV ) infected patients , three subjects were injection users and
Human Immunodeficiency Virus (
HIV ) also infected two of them . -
pubmed
Intra - amniotic administration of
E coli lipopolysaccharides causes sustained
inflammation of the fetal skin in
sheep . -
pubmed
At diagnosis , 73 % of the total 22
patients had
nerve function impairment (
NFI ) . -
pubmed
Autonomic function ( chi(2)= 5.5 , P= 0.019 ) and NCS ( chi(2)= 7.765 , P= 0.01 ) were significantly more altered in
MB than PB
patients . -
pubmed
A high prevalence of
neuropathy was observed in newly diagnosed
patients . -
pubmed
Cystic fibrosis (
CF )
patients are suffering from multiple often chronic
endobronchial infection . -
pubmed
While current standard of treatment of
ABPA in
CF patients is to suppress the
allergy related symptoms by administration of
glucocorticoids ,
itraconazole (
ITRA ) , administered orally at high doses , can alleviate the symptoms of
ABPA . -
pubmed
The data indicate that
ITRA nanosuspension represents an interesting formulation for inhaled administration in
CF patients suffering from
ABPA . -
pubmed
Molecular diagnosis of
echovirus 30 as the etiological agent in an outbreak of
aseptic meningitis in Panama : May - June 2008 . -
pubmed
CONCLUSION :
Echovirus 30 is reported as the likely cause of an outbreak of
aseptic meningitis in Panama , the first since the 1980s . -
pubmed
As more effective systemic therapy is being used in
patients with
solid tumors ,
patients with
cancer live longer and are ultimately at higher risk for CNS
metastases . -
pubmed
After the induction of
pulmonary inflammation and
fibrosis via intratracheal delivery of
bleomycin sulfate ,
mice were i.v . -
pubmed
METHODS : Male
Wistar rats were assigned into seven groups ( six in each ): intact ( control ) ; sham - operated ; nontreated
rats subjected to
ischemia and reperfusion ( IR ) ;
ramiprilat - treated
rats with ( Ram+IR ) and without
ischemia ( Ram ) ;
losartan treated with ( Los+IR ) and without
ischemia ( Los ) . -
pubmed
METHODS : From May 2010 to November 2011 , 61
patients treated for 74
metastases were included in the study . -
pubmed
Patients responding to the treatment at d8 had a significative longer
pain relapse free survival ( PRFS ) compared to
patients not responding ( 3.38 weeks vs 0.3 weeks ; p & lt ; 0.001 ) . -
pubmed
BACKGROUND : Active surveillance , followed by delayed definitive treatment for those who develop evidence of significant
cancer progression , is now a recognised management strategy for selected
men with low risk
prostate cancer . -
pubmed
Prostate carcinoma (
PCa ) was detected in 75
patients in the first group ( 47.5 % ) and in eight of the second group ( 40.0 % ) . -
pubmed
In the first group ,
PCa was detected with targeted biopsies alone in 18
patients ( 24 % ) , with nontargeted biopsies alone in 23 ( 30.7 % ) , and with both in 34 ( 45.3 % ) . -
pubmed
Twenty - six
patients ( 29.8 % ) were diagnosed with
malignant neoplasm . -
pubmed
All
patients with malignant LNs ( n = 5 ; 6.4 % ) were diagnosed with
papillary carcinoma . -
pubmed
CONCLUSIONS : In
patients undergoing diagnostic hemithyroidectomies , routine level VI LND was able to identify LN
metastases in 6.4 % of
patients . -
pubmed
Human cytomegalovirus (
HCMV ) , a betaherpesvirus , establishes latency in CD34(+ ) hematopoietic progenitor cells during natural
infections in the body . -
pubmed
Impact of left anterior line on left atrial appendage contractility in
patients who underwent catheter ablation for chronic
atrial fibrillation . -
pubmed
METHODS : This study included 46
patients ( 30
men , mean age 58 + - 9 years , group 1 ) with persistent
AF who underwent catheter ablation including LAL . -
pubmed
Thirty
patients with paroxysmal
AF who received no additional LA ablation were compared as control group ( 21
males , mean age 56 + - 8 years , group 2 ) . -
pubmed
In 8/11
patients , the first and second source of
epileptic activity as found by DICS were concordant with the operative resection site ; these
patients became
seizure free after
epilepsy surgery . -
pubmed
[ The value of changes in end - tidal
carbon dioxide pressure induced by passive leg raising test in predicting fluid responsiveness in mechanically ventilated
patients with
septic shock ] . -
pubmed
OBJECTIVE : To test whether the changes of partial end - tidal
carbon dioxide pressure ( PETCO2 ) during passive leg raising ( PLR ) predict fluid responsiveness in mechanically ventilated
patients with
septic shock . -
pubmed
METHODS : Forty - two mechanically ventilated
patients with
septic shock admitted from January 2012 to November 2012 were prospectively recruited . -
pubmed
CONCLUSIONS : The change of PETCO2 induced by passive leg raising is a non - invasive and easy way to predict fluid responsiveness in mechanically ventilated
patients with
septic shock . -
pubmed
In the
patients with
catatonia , it is recommended to examine whether they have a general medical disease . -
pubmed
We present two
catatonic elder
patients . -
pubmed
In case of
benzodiazepine resistance or
malignant catatonia , it should be considered electroconvulsive therapy , but it needs to be carefully implemented for elder
patients . -
pubmed
Abscisic acid (
ABA ) inhibits the production of
ethylene induced by
water stress in excised
wheat leaves and counteracts the stimulatory effect of
6 - benzyladenine ( BA ) on this process . -
pubmed
The aim of the present prospective study was to investigate , in
colorectal cancer patients , the relationship between preoperative
tumour marker concentrations and various clinical variables . -
pubmed
METHODS : The study prospectively enrolled 131 consecutive
patients with a confirmed diagnosis of colorectal
carcinoma and 131 age- and sex - matched control subjects with no
malignancy . -
pubmed
Levels of both
tumour markers were significantly elevated in the presence of distant
metastasis in the
patient group ( p = 0.005 for cea ; p = 0.004 for ca 19 - 9 ) . -
pubmed
CONCLUSIONS : Preoperative levels of cea and ca 19 - 9 might provide an estimate of lymph node invasion and distant
metastasis in
colorectal cancer patients . -
pubmed
This report describes a case of
lung cancer with
sarcoid reaction following chemoradiotherapy , showing false - positive accumulation of
( 18 ) F - fluorodeoxyglucose on positron - emission tomography in a 55 - year - old
man . -
pubmed
BACKGROUND :
Diabetic macular oedema (
DMO ) is the commonest cause of
vision loss in
people with
diabetes . -
pubmed
METHODS : We have used proteomic techniques to identify the protein changes induced by threshold intensity retinal laser treatment in a
rodent model of
diabetic retinopathy . -
pubmed
Retinae were obtained from
diabetic Dark Agouti
rats 8 weeks following laser treatment . -
pubmed
METHODS : This preliminary study utilized pre - symptomatic and post - symptomatic serum from a sample of 100 incident population - based US military
veterans with
MS along with 100 matched healthy controls . -
pubmed
CONCLUSIONS : Compared with healthy controls , differential proteomic changes were noted in the serum of
patients with
MS that preceded the onset of symptomatic disease . -
pubmed
Primary immunodeficiency disorders enable identification of genes with crucial roles in the
human immune system . -
pubmed
METHODS : As the initial cross - sectional analysis of a longitudinal study , we studied the association of brain volumes and somatic disease burden with neuropsychological outcomes , including measures of intelligence , memory , and attention in 20
patients with attenuated
MPS II with a mean age of 15.8 . -
pubmed
Normal age - related volume increases in white matter were not seen in
MPS II patients as they were in controls . -
pubmed
We investigated whether episodic
hypotension is associated with
tissue infarction in
subjects with
syncopal symptoms at
stroke onset . -
pubmed
Subjects with severe
large vessel stenosis were excluded , while cases were referred for
syncope unit investigation . -
pubmed
RESULTS : thirty - eight of 772
stroke patients described
presyncope or
syncope at
stroke onset and had patent large vessels ( 4.9 % of all
strokes ) . -
pubmed
Cases exhibited greater orthostatic BP drop than controls , P & lt ; 0.05 Twenty - four
patients were diagnosed with
vasovagal syncope through head - up tilt symptom reproduction , 9 with
orthostatic hypotension , 4 with
cardiac syncope and 1 with
carotid sinus syndrome . -
pubmed
Nineteen ( 50 % )
patients had an acute
infarct on MRI , 14 of these were in the arterial borderzone ( 73.6 % ) . -
pubmed
In
children with
congenital heart disease ,
tracheobronchial compromise is uncommon but potentially life - threatening . -
pubmed
We present an overview of the etiologies of
tracheobronchial lesions typically seen in
children with
congenital heart disease and review management options for these lesions . -
pubmed
OBJECTIVE : To evaluate the detection of
pituitary lesions at 7.0 T compared to 1.5 T MRI in 16
patients with clinically and biochemically proven
Cushing ' s disease . -
pubmed
CONCLUSION : The interobserver agreement of image assessment for 7.0 T MRI in
patients with
Cushing ' s disease was good , and lesions were detected more accurately with 7.0 T MRI . -
pubmed
OBJECTIVES : The aim of this study was to find out potential relationships between serum , salivary and tissue
protoporphyrin IX (
PX ) levels in
subjects with or without oral precancerous and
cancerous lesions . -
pubmed
This study aimed to determine the susceptibility profile of Brazilian
Brucella abortus isolates from
cattle to eight antimicrobial agents that are recommended for the treatment of
human brucellosis and to correlate the susceptibility patterns with origin , biotype and MLVA16 - genotype of the
strains . -
pubmed
abortus strains isolated from
cattle in Brazil were sensitive to the antimicrobials commonly used for the treatment of
human brucellosis ; however , a considerable proportion of
strains showed reduced susceptibility to
rifampicin and two
strains were considered multidrug resistant . -
pubmed
The
patients were divided into 3 groups according to the World Health Organization
body mass index (
BMI ) values : normal weight group (
BMI & lt;25 kg / m(2 ) ; group 1 ) ,
obese group (
BMI = 30 - 34 kg / m(2 ) ; group 2 ) , and severely
obese group (
BMI & gt;=35 kg / m(2 ) ; group 3 ) . -
pubmed
Overweight women (
BMI = 25 - 29 kg / m(2 ) ) were omitted . -
pubmed
METHODS : This hospital - based case - control study included 120
NSCLC patients and 360 healthy controls . -
pubmed
RESULTS : The expression of let-7c and miR-152 in plasma were found to be downregulated in the
patients with
NSCLC . -
pubmed
CONCLUSION : It was found that let-7c and miR-152 are significantly reduced in plasma samples of
NSCLC patients . -
pubmed
These findings suggest that detection of circulating let-7c and miR-152 can be developed into a noninvasive and rapid diagnostic tool for the
individuals with
NSCLC . -
pubmed
Thirty
patients with precancerous or suspected malignant
laryngeal lesions underwent microlaryngoscopy , during which samples were taken for cytological , immunocytochemical , and histological analysis . -
pubmed
Our findings suggest that ARBs , as a class , are more effective than placebo therapy in long - term BP lowering in
patients with essential
hypertension . -
pubmed
METHODS : One hundred and sixteen imaging studies of 94
patients ( CT n = 65 ; MRI n = 51 ) diagnosed with AE ( n = 55 ) or
ICC ( n = 39 ) were retrospectively reviewed by two blinded radiologists for lesion features including enhancement pattern and matrix composition . -
pubmed
POPULATION : One hundred and forty
patients of both genders , mean age of 64.8 + -8.9 years , with
knee osteoarthritis and chronic
knee pain . -
pubmed
BACKGROUND : There is a growing body of evidence linking
micronutrient deficiencies and
malaria incidence arising mostly from
P. - pubmed
Close monitoring of the
patient symptoms , ocular motility , intraocular pressure and the fundus showed no evidence of compressive
optic neuropathy or perfusion abnormalities through orbital vessels . -
pubmed
The first clinical trials of
Zika virus vaccine candidates will begin in Q3/4 2016 but the pathway to licensure for a
Zika virus vaccine is expected to take several years . -
pubmed
We report a case of a 70 - year - old
woman with generalized
pustular psoriasis (
GPP ) who responded well to infliximab therapy and
adalimumab therapy after secondary failure of
infliximab therapy , but did not respond to
ustekinumab therapy . -
pubmed
BACKGROUND : Knowledge of hatha yogic exercises , the most used yoga style , for increasing functional capacity in
patients with
obstructive pulmonary diseases remains limited . -
pubmed
POPULATION : Thirty - six
patients with
obstructive pulmonary disease . -
pubmed
HY seems feasible and safe as a form of physical exercise for
pulmonary disease patients . -
pubmed
OBJECTIVE : People living with
HIV (
PLWH ) have chronic immune activation and increased
cardiovascular disease (
CVD ) risk . -
pubmed
The aim of this study was to compare the anti - PD1 safety and efficacy in
patients with previous severe
toxicity to IPI versus in those showing moderate and no previous IPI - related AEs . -
pubmed
METHODS : Fifty - six consecutive
patients requiring reconstructive procedures following the extirpation of
tumors were recruited . -
pubmed
BACKGROUND : This study aimed at investigating the prevalence and risk factors of
bovine thelaziosis , performed in the southeast of Iran , an endemic area for Iranian Sistani
cattle . -
pubmed
RESULTS : The overall prevalence for
thelaziosis was 50 of 1924
cows ( 2 . -
pubmed
The difference in the seasonal variations of prevalence and the intensity of
infection were significant , however , no significant correlation between prevalence , sex and age of
cattle was noted . -
pubmed
CONCLUSION :
Bovine thelaziosis needs special attention by veterinarians in the differential diagnosis of ocular manifestations and considering its impact on
cattle production . -
pubmed
Gram - negative bacteria are responsible for a large proportion of
antimicrobial - resistant infections in
humans and animals . -
pubmed
MATERIAL AND METHODS : The study included
patients with
ischemic stroke which was confirmed clinically and by MRI ( n=1200 ) , the control group consisted of 500
patients without
cardiovascular disease . -
pubmed
Risk of
myocardial infarction in
patients with
atrial fibrillation using
vitamin K antagonists ,
aspirin or direct acting oral anticoagulants . -
pubmed
AIM : Direct - acting oral anticoagulants ( DOACs ) have become available for the prevention of
stroke in
patients with
atrial fibrillation (
AF ) . -
pubmed
The objective of the present study was to evaluate the risk of
AMI in
patients with
AF who are exposed to either
VKAs ,
DOACs or low - dose ( & lt ; 325 mg )
aspirin . -
pubmed
PURPOSE : Daytime complaints such as
memory and attention deficits and failure to accomplish daily tasks are common in
insomnia patients . -
pubmed
The aim of this study was to investigate the hemodynamic response patterns of
patients with
chronic insomnia disorder (
CID ) using the noninvasive and low - cost functional neuroimaging technique of multichannel near - infrared spectroscopy ( NIRS ) in order to identify changes of neural function associated with cognitive performance . -
pubmed
PATIENTS AND METHODS : Twenty - four
CID patients and twenty - five healthy controls matched for age , right - hand dominance , educational level , and gender were examined during verbal fluency tasks ( VFT ) using NIRS . -
pubmed
CID patients showed hypoactivation in the PFC during the cognitive task . -
pubmed
Acquisition of
Cholangiocarcinoma Traits during Advanced
Hepatocellular Carcinoma Development in
Mice . -
pubmed
In this study , we investigated the potential acquisition of CC - like traits during advanced development of
HCC in
mice . -
pubmed
Primary and rare high - grade
HCC developed in a genetic
mouse model . -
pubmed
A
mouse model of highly efficient
HCC invasion and
metastasis by orthotopic transplantation of
liver cancer organoids propagated from primary
tumors in the genetic model was further developed . -
pubmed
Invasive / metastatic
tumors developed in both models closely recapitulated advanced
human HCC and displayed a striking acquisition of CC - related pathologic and molecular features , which was absent in the primary
HCC tumors . -
pubmed
- No Title - We are reporting the case of an 82 - year - old Yemeni patient , renal transplant recipient who was admitted to our institution and who subsequently developed disseminated
infection with
Saprochaete capitata . -
pubmed
This is the second case to our knowledge of
infection with
Saprochaete capitata in a renal transplant patient . -
pubmed
BACKGROUND : Focal radiation therapy has gained of interest in treatment of
patients with primary
prostate cancer (
PCa ) . -
pubmed
OBJECTIVES : To examine ( 1 ) the effectiveness of therapeutic play in reducing
anxiety and negative emotional manifestations among
children undergoing cast - removal procedures and ( 2 ) the satisfaction of parents and cast technicians with cast - removal procedures . -
pubmed
OUTCOME MEASURES :
Children 's
anxiety level , emotional manifestation and heart rate . -
pubmed
RESULTS : Findings suggested that therapeutic play assists
children aged 3 - 7 to reduce
anxiety levels with mean differences between the intervention and control group was -20.1 ( 95 % CI -35.3 to -4.9 ; p=0.01 ) . -
pubmed
CONCLUSION : Therapeutic play effectively reduces
anxiety and negative emotional manifestations among
children undergoing cast - removal procedures . -
pubmed
He was a 12 - yr - old
CH patient and treated with
levothyroxine . -
pubmed
The Efficacy of
Amifostine against Multiple - Dose
Doxorubicin - Induced
Toxicity in
Rats . -
pubmed
Our results showed that
amifostine successfully protected
rats against multiple - dose
doxorubicin - induced
toxicity by complex , and still not fully elucidated mechanisms of action . -
pubmed
Changes in proteome solubility indicate widespread proteostatic disruption in
mouse models of
neurodegenerative disease . -
pubmed
This hypothesis has been supported by previous work in our laboratory , as evidenced by the perturbation of cytosolic protein solubility in response to
amyloid plaques in a
mouse model of
Alzheimer ' s amyloidosis . -
pubmed
In the current study , we demonstrate changes in proteome solubility are a common pathology to
mouse models of
neurodegenerative disease . -
pubmed
Overall , our data suggest that
neurodegenerative proteinopathies modeled in
mice impose a burden on the proteostatic network that diminishes the ability of neural cells to prevent aberrant conformational changes that alter the solubility of hundreds of abundant cellular proteins . -
pubmed
In vivo experiments using a
mouse xenograft model revealed that combination therapy with
NBT and
ADR significantly reduced
tumor volume by 84.15 % . -
pubmed
It includes 36
patients suffering from different
retinal pathologies including
diabetic retinopathy , age related
macular degeneration , and
vitreomacular interface disorders using multicolor optical coherence tomography as a screening tool . -
pubmed
Hemodynamic parameters were compared in
AKI vs. no -
AKI patients at the time of admission and 48 h thereafter . -
pubmed
Exercise During Adolescence Attenuated
Depressive - Like Behaviors and Hippocampal Mitochondrial Dysfunction Following Early Life Stress in Adult Male
Rats . -
pubmed
Maternal separation stress ( MS ) model to male
rats ( postnatal day or PND2 - PND14 ) were performed to determination of
depressive - like behaviors using the forced swimming test , splash test , and mitochondrial function in the hippocampus . -
pubmed
METHODS :
Adolescents aged 10 to 14 years with
PFP were included ( N = 151 ) . -
pubmed
CONCLUSION : A treatment strategy focusing on activity modification and load management was associated with high rates of successful outcome among
adolescents with
PFP at 12 and 52 weeks . -
pubmed
BACKGROUND : Anger and stress can trigger episodes of
atrial fibrillation (
AF ) in
patients with a history of
AF . -
pubmed
METHODS : In this prospective , controlled , electronic diary - based study of emotions preceding
AF ,
patients with a history of paroxysmal or persistent
AF ( N = 91 ) recorded their rhythm on event monitors at the time of
AF symptoms and completed a diary entry querying mood states ( eg , anger and stress ) for the preceding 30 minutes ( pre - AF " case period " ) for 1 year . -
pubmed
A total of 163 symptomatic
AF episodes ( in 34
patients ) and 11,563 Holter - confirmed
sinus rhythm control periods had associated diary data . -
pubmed
The Gram - negative bacterium
Klebsiella pneumoniae is an opportunistic pathogen , which can cause life - threatening
infections such as
sepsis . -
pubmed
Prognostic value of serial
lactate levels in septic
patients with and without
shock . -
pubmed
To analyze the prognostic value of
lactate levels for day-7 and in - hospital mortality , in septic
patients with and without
shock . -
pubmed
In the period November 2011 - December 2016 , we enrolled 268
patients , admitted to our High - Dependency Unit with a diagnosis of
sepsis . -
pubmed
Among
patients with
shock , an analysis for repeated measures confirmed a more marked
lactate level reduction in survivors compared with non - survivors , both by day-7 and in - hospital mortality ( p = 0.057 and p = 0.006 ) . -
pubmed
Complete response in
patients with locally advanced
rectal cancer after neoadjuvant treatment with
nivolumab . -
pubmed
In all , 88
patients with
periodontitis and 79 healthy controls ( HCs ) were enrolled in the study . -
pubmed
Novel therapies for
hemophilia , including non - factor replacement and in vivo gene therapy , are showing promising results in the clinic , including for
patients having a history of inhibitor development . -
pubmed
When delivered as a protein to
hemophilia A mice , a selected bi - paratopic sdAb significantly reduced the
blood loss in a model of
acute bleeding injury . -
pubmed
We then packaged this sdAb in a hepatotropic AAV8 vector and tested its safety and efficacy profile in
hemophilic mouse models . -
pubmed
We show that the long - term expression of the bi - paratopic sdAb in the liver is safe and poorly immunogenic , and results in sustained correction of the
bleeding phenotype in
hemophilia A and B
mice , even in the presence of inhibitory antibodies to the therapeutic clotting factor . -
pubmed
Clinicopathological characteristics and prognostic factors for
canine multicentric
non - indolent T - cell lymphoma : 107 cases . -
pubmed
The aim of this retrospective study was to determine outcomes and prognostic factors of 107
dogs with multicentric
non - indolent T - cell lymphoma (
TCL ) receiving
lomustine - based ( 70 % ) and non -
lomustine - based ( 30 % ) treatment . -
pubmed
Multicentric non - indolent
TCL in
dogs is an aggressive
cancer with new possible prognostic factors . -
pubmed
ANIMAL(S ):
Nonobese diabetic ( NOD )/ severe combined immunodeficiency (
SCID ) female
mice . -
pubmed
Clinical characterization of
status epilepticus in childhood : a retrospective study in 124
patients . -
pubmed
We discuss culture , status , religion , and social influences , including insights into the complexities of cultural " blind
spots " which complicate efforts by NGOs to improve working
donkey welfare when the influence of different cultural and societal pressures are not recognized or acknowledged . -
pubmed
BACKGROUND : This study will aim to assess the effectiveness of Mozart 's Music ( MM ) for the management of
patients with
drug - resistant epilepsy (
DRE ) . -
pubmed
RESULTS : This study will summarize high quality randomized controlled trials to appraise the effectiveness and safety of MM for the treatment of
patients with
DRE . -
pubmed
Postoperative complications and perioperative management in
patients on hemodialysis undergoing lung resection . -
pubmed
OBJECTIVES : The rate of lung resection in
patients on hemodialysis ( HD ) is increasing with the increasing number of
HD . -
pubmed
The study aimed to investigate the perioperative management and
postoperative complications of lung resection in
HD patients . -
pubmed
Thirty - eight
patients had
lung cancer . -
pubmed
The reason for
HD was
diabetic nephropathy in 19
patients ,
nephrosclerosis in 10 , and miscellaneous in 14 . -
pubmed
The frequency of
bronchial calcification is relatively high in
HD patients , and reinforcement of the calcified bronchial stump should be considered during lobectomy . -
pubmed
Patients with abdominal wall masses as primary
malignant tumours or
metastatic disease are rare . -
pubmed
We present a case series of three
patients who presented with abdominal
adenocarcinoma of unknown primary origin . -
pubmed
All
patients ultimately underwent surgical resection and final pathology showed a gynaecological origin for these
tumours . -
pubmed
Patient demographics , incidence and patterns of
injury , outcomes , and ED resources use were evaluated as part of the study . -
pubmed
BACKGROUND : A combination of central muscle relaxants ,
chlorzoxazone and
baclofen (
chlorzoxazone -
baclofen ) , has been proposed for treatment of
cerebellar symptoms in
human spinocerebellar ataxia . -
pubmed
P elements were first discovered in the
fruit fly Drosophila melanogaster as the causative agents of a
syndrome of aberrant genetic traits called
hybrid dysgenesis . -
pubmed
METHODS : We retrospectively analyzed 207
patients who were hospitalized with
SARS - CoV-2 pneumonia at the Self - Defense Forces Central Hospital in Tokyo , Japan . -
pubmed
METHODS : Consecutive
patients who underwent EMR for a
LNPCP > = 20 mm were evaluated . -
pubmed
METHODS : MR imaging was performed at 3 Tesla in 12 healthy
subjects and 3
patients with various
kidney pathologies (
fibrotic kidney disease , failed renal graft , and renal masses ) . -
pubmed
Neonatal infection with
mouse thymic virus : effects on cells regulating the antibody response to type III
pneumococcal polysaccharide . -
pubmed
Biosynthesis of different
gangliosides in two types of
rat ascites hepatoma cells with different degrees of cell adhesiveness . -
pubmed
Since 1972 , 367
patients with chronic
low - back pain have been treated by electrical stimulation ( e.s . ) -
pubmed
Patients with
herniated disc lesions and
spondylitis and allied conditions were included . -
pubmed
75 - 100 %
pain relief was obtained by 53 % of the
patients 50 %
pain relief by 27 % and there was no improvement in 20 % of
patients . -
pubmed
In a follow - up of 208
patients , 6 - 36 months later , approximately 70 % stated that
pain relief was similar to that obtained at the end of treatment . -
pubmed
The present study examines the dose - response pattern of
delta 9 - tetrahydrocannabinol self - injection in naive
rats at 80 % reduced
body weight and 100 %
body weight , both conditions with a fixed - time 1 min ( FT-1 ) food delivery schedule . -
pubmed
The results indicated that food deprived
animals tested on a FT-1 min schedule self - injected low doses of
delta 9 - THC at a higher rate than those animals at 100 %
body weight and on a FT-1 min schedule . -
pubmed
Animals at 80 % reduced
body weight without a schedule did not differ from
rats self - injecting
delta 9 - THC at free feeding situation . -
pubmed
These findings suggest that
rats without previous history of
drug dependence self - administer low doses of
delta 9 - THC and that the interaction between the food deprivation state and the environmental contingencies introduced by a FT-1 min schedule is a critical variable in the acquisition period . -
pubmed
[ Survival of
5 - fluorouracil - treated
stomach cancer patients in the far - advanced stages ] . -
pubmed
Umder study was the survival rate in 73
patients treated routinely with
5 - fluoruracil for
recurrences and
metastases of
gastric cancer . -
pubmed
The compared groups of
patients did not differ reliably in such prognostic factors as the
tumor spread to the onset of chemotherapy and duration of the interval since the primary operation till
tumor progression . -
pubmed
[ Cytophotometric determination of the DNA concentration of the nuclei of hepatocytes of
rats trained to
hypoxia ] . -
pubmed
Computed tomographic scanning in
patients with
lymphoma . -
pubmed
The spinal accessory - nerve - sparing operation is offered as an alternative to the classic procedure in all
patients in whom the nerve is not directly invaded by
cancer . -
pubmed
A reversed rocket immunoelectrophoresis technique , applying serum samples to antigen - containing gel , is described for quantitation of
human antibodies to
diphtheria and
tetanus . -
pubmed
Because of the rarity of
Darier ' s disease (
keratosis follicularis ) occurring as an acute ,
eruptive disease in a mature adult , a case with sudden onset in a 51 - year - old white
man is reported . -
pubmed
Physiologic effects of transfusing red blood cells with high or low affinity for
oxygen to passively hyperventilated ,
anemic baboons : systemic and cerebral
oxygen extraction . -
pubmed
These findings lend support to the recommendation that preserved red cells with normal or elevated
2,3 DPG levels be administered to
patients in
hemorrhagic or
septic shock , and to
patients subjected to extracorporeal circulation during cardiac surgery in order to lessen the demand for increased blood flow and to ensure adequate tissue oxygenation during the postoperative period . -
pubmed
Chronic renal disease and
potassium depletion in
cats . -
pubmed
Renal tumours in
male rats and those of liver in
murine females had been described also after inhalatory exposure to unleaded
gasoline . -
pubmed
A reliable epidemiological study in occupationally gasoline exposed
humans is still not available ( higher rate of
tumours in
workers of chemical petrol processing industry due to the influence of
gasoline appears to be an indirect proof , because apart from
gasoline also other substances are involved simultaneously ) . -
pubmed
Pharmacological aspects of
arthritis induced by a
muramyl dipeptide analogue in
rats . -
pubmed
Bacterial
ileocecitis caused by
Escherichia coli O157 : H7 . -
pubmed
Escherichia coli O157 : H7 is most commonly linked to
hemorrhagic colitis and the
hemolytic uremic syndrome . -
pubmed
Diagnostic ultrasound was used to demonstrate terminal ileum abnormalities suggestive of
bacterial ileocecitis , a recently described entity that resembles
acute appendicitis , in a patient whose stool culture yielded
E. - pubmed
A
somatostatin analogue is protective against retrograde
bile salt - induced
pancreatitis in the
rat . -
pubmed
Phagocytic cells in
middle ear effusion obtained from
patients with acute or
chronic otitis media , have antibacterial activity which is an element of the host defense system . -
pubmed
The
children with
CMPI were divided into three groups according to clinical features : delayed - onset CMPI with
gastrointestinal symptoms ( n = 8) ; immediate - onset
CMPI with
gastrointestinal and skin symptoms ( n = 8) ; and immediate - onset
CMPI with
skin symptoms only ( n = 8) . -
pubmed
The CMPI groups were compared with
children with untreated ( n = 9 ) or treated ( n = 8)
coeliac disease and a control group ( n = 22 ) . -
pubmed
Sera from the
children were examined for
cytotoxic effects using lymphocytes from healthy
adults as effector cells and
radiolabelled beta - lactoglobulin - coated erythrocytes from the same donor as target cells . -
pubmed
Sera from
children with
CMPI and gastrointestinal symptomatology showed a significantly increased capacity to induce ADCC reactivity as compared with controls . -
pubmed
In contrast , sera from
children who had an immediate - onset
CMPI with only
skin symptoms mediated no such increase in ADCC reactivity . -
pubmed
Twenty - seven
patients had inoperable
liver metastases of colorectal origin . -
pubmed
Five / ten
patients developed extrahepatic
metastases . -
pubmed
Ultrastructural , immunohistochemical , and cytogenetic study of a malignant
peripheral neuroectodermal tumor in a
patient seropositive for
human immunodeficiency virus . -
pubmed
[ Ultrastructural demonstration of the
human papilloma virus (
HPV ) in
oral proliferative lesions ] . -
pubmed
The
Human Papilloma Virus (
HPV ) has been found in a series of
benign proliferative lesions of the skin and mucosa . -
pubmed
The purpose of this report is to present a 5 - year experience of a prospective study on lymph node
metastasis in
patients with
ovarian cancer through retroperitoneal lymphadenectomy at the Peking Union Medical College Hospital . -
pubmed
A prospective randomized double blind investigation was made in 24
multiple injured patients . -
pubmed
Acquired circulating anticoagulants in
children with
acquired immunodeficiency syndrome . -
pubmed
As such , careful laboratory diagnosis of the cause of
abnormal coagulation test results is necessary for
children with
AIDS . -
pubmed
We compared two selected groups of
patients with acute
Guillain - Barre syndrome requiring artificial ventilation . -
pubmed
Body weight change was decreased in
rats . -
pubmed
Morphologic changes in the kidneys with accompanying
polyuria and
hematuria /
hemoglobinuria were observed in male
rats . -
pubmed
The only effect observed at 25 ppm was a low incidence of
hematuria /
hemoglobinuria in male
rats . -
pubmed
The immune response to A - Jax
strain mouse organs in normal and A - Jax
strain mouse liver tolerant
rabbits . -
pubmed
Tubular lesions produced by autoantibodies to tubular basement membrane in
human renal allografts . -
pubmed
Specific role of each
human leukocyte type in
viral infections . -
pubmed
[ Isolation of mutant
bacterial strains showing abnormal biosynthesis of the cell wall ] . -
pubmed
[ Acute
bacterial endocarditis due to
Mima polymorpha ] . -
pubmed
Concentration of
phenylalanine in the blood serum of
patients with various degrees of
phenylketonuria . -
pubmed
The data are discussed in view of their significance for therapy of
patients with
basal ganglia disorders , such as
patients suffering from
Parkinson ' s disease . -
pubmed
Yield of unpredicted bone - marrow
relapse diagnosed by routine marrow aspiration in
children with
acute lymphoblastic leukaemia . -
pubmed
1466
children with
acute lymphoblastic leukaemia had routine bone - marrow aspiration at the end of each 84 - day cycle of maintenance therapy . -
pubmed
In the low - risk , moderate - risk , and high - risk
leukaemic patients 0.4 % , 0.5 % , and 0.8 % , respectively , of the total routine bone - marrow aspirations yielded an unpredicted bone - marrow
relapse . -
pubmed
The median survival after
relapse in the predicted group was significantly shorter than that in the unpredicted group , but the eventual outcome was the same in both groups , 95 % of all
patients dying within 24 months of
relapse . -
pubmed
Salmonella strains sent for serotyping were inoculated into a tube with broth which was used as H antigen and , after heating also as
O antigen . -
pubmed
A quantitative anatomic study of 54 cardiac specimens with
aortic atresia is related to surgical treatment of
patients with
aortic atresia and
hypoplastic left heart syndrome . -
pubmed
In the
rat ,
( phenylthio-4 phenylamino )- 2 nicotinic and [ ( chloro-4 phenylthio )- 4 phenylamino ]- 2 nicotinic acids inhibit the
hypotensive prostaglandin - mediated action of
arachidonic acid . -
pubmed
The postmenopausal
women with
primary hyperparathyroidism had the B -
ALP 4.30 + /- 0.54 mukat / l , the urinary
hydroxyproline excretion 205.2 + /- 22.2 mmol / mol
creatinine and urinary
calcium excretion 8.9 + /- 0.5 mmol/24 hours , significantly increased in comparison with the group of
women with menstrual cycle and
primary hyperparathyroidism who had B -
ALP 2.12 + /- 0.43 mukat / l , the urinary
hydroxyproline excretion 119.0 + /- 14.9 mmol / mol
creatinine and urinary
calcium excretion 7.7 + /- 0.4 mmol/24 hours . -
pubmed
Of 107 women investigated for frequency of micturition and
dysuria , 21 had
gonorrhoea , 14
chlamydial urethritis , eight an
Escherichia coli urinary tract infection , 18
candidosis , 12
trichomoniasis , and four asymptomatic
genital herpes . -
pubmed
There were no differences in the distribution of T cell subsets between healthy
volunteers and
patients with active
psoriasis . -
pubmed
Squamous cell carcinoma of the skin subsequently developed in 2 of 3
PUVA - treated
patients with the lowest percentages of T4 - bearing cells . -
pubmed
Immunopathology of rhino
mouse , an autosomal recessive mutant with
murine lupus - like disease . -
pubmed
Identifying the acutely ill
patient with
asthma . -
pubmed
We studied 77
patients suffering acute
asthma to identify those who needed hospitalization . -
pubmed
Animal experiments have indicated that
presbycardia as a distinctive entity does exist but that it does not , in and of itself , cause
heart failure in large numbers of individuals . -
pubmed
Diagnosis is altered in aged
individuals because
symptoms and signs may not be those classically described and taught . -
pubmed
These
patients were divided into 3 diagnostic categories :
myofacial pain dysfunction syndrome (
MPD ) [ 18 ] ,
arthritis of the temporomandibular joints (
TMJ arthritis ) , and
trigeminal neuralgia . -
pubmed
They consisted of an normal , or non - patient group , a group of
arthritis patients , and a group of
movement disorder patients attending a neurology clinic . -
pubmed
Among the
facial pain patients and the normal controls few differences were found with regard to
anhedonia and
depression , The
arthritis and neurology
patients produced significantly higher
depression and
anhedonia scores than did several of the
facial pain groups . -
pubmed
Pain estimate ranged from 0 for control , to a mean of 67.6 + /- 31.3 for the
trigeminal neuralgia patients with the
MPD ( means = 56.2 + /- 32.5 ) and the
TMJ arthritis patients ( means = 46.7 + /- 30.8 ) somewhat lower . -
pubmed
In the present study of the brains from 18
patients who had died from
Krabbe disease at 7 - 37 months of age , the concentration of
galactosylceramide of cerebral and cerebellar white matter was severely reduced to 10 - 20 % of that in age - matched controls . -
pubmed
We describe a case of necrotizing
arteritis of the brain in a 26 - year - old
man who presented as
organic brain syndrome . -
pubmed
OBJECTIVES : This study sought to assess the value of quantitative coronary arteriography in predicting an
ischemic response at exercise echocardiography and
technetium-99 m 2 - methoxy isobutyl isonitrile (
mibi ) single - photon emission computed tomography ( SPECT ) in
patients with single - vessel disease of the left anterior descending coronary artery . -
pubmed
BACKGROUND : The relation between severity of
coronary stenosis and ischemic response to exercise echocardiography and perfusion scintigraphy in
patients with single - vessel left anterior descending
coronary artery disease is not well established . -
pubmed
METHODS : Thirty - one
patients without a previous
myocardial infarction who had isolated
stenosis of varying degrees in the proximal or midportion of the left anterior descending coronary artery were studied . -
pubmed
Genetic studies in the
nematode Caenorhabditis elegans and in the
fruit fly Drosophila melanogaster have led to the isolation of genes that are specifically required for the induction of programmed cell
death . -
pubmed
METHODS : A critical prospective analysis of 121
patients , referred to two university centers after ESWL had been exhausted as a treatment modality for
upper urinary tract calculi , was performed . -
pubmed
Patients were subdivided into the following groups : failure to clear fragments , failure to fragment , difficulty in
calculus localization , and failure due to inherent
upper urinary tract obstruction . -
pubmed
The frequency of elevated titers was 8.6 % in healthy
subjects , 76.2 % in
patients with untreated
hyperthyroidism and
diffuse goiter , 80.7 % in
patients with relapse of
hyperthyroidism . -
pubmed
83.4 % of
patient with hyperfunction changed spontaneously to
hypothyroidism and 71.5 % of
patients with
hypothyroidism and
goiter had antibodies above the normal range . -
pubmed
Unexpectedly low prevalence of autoantibodies were detected in
patients with
primary myxoedema without
goiter ( 48.2 % ) and in
patients with
endocrine ophthalmopathy and
euthyroidism ( 33.2 % ) . -
pubmed
In the subgroup of
patients with
hyperthyroidism under
methimazole treatment we found an incidence of positivity of 56 % and the mean of positive values was lower compared with the untreated ones . -
pubmed
In 42.8 % of
patients with
hyperthyroidism and
diffuse goiter treated successfully by
methimazole , surgery or
radioiodine elevated concentrations of antibodies could be detected , however they were in remission for more than five years . -
pubmed
However ,
nephrocalcinosis is noted in many
children treated with this therapy . -
pubmed
The management of long
bone fractures in the
head - injured polytrauma patient . -
pubmed
The
polytrauma patient who sustains a significant
head injury ( head and neck Abbreviated Injury Scale of 3 or greater ) will require prolonged and technically demanding operative intervention for musculoskeletal and associated
soft tissue trauma . -
pubmed
The presence of a
head injury may delay the immediate surgical intervention for long
bone injuries , which has proven to have major advantages for
patient care and well - being . -
pubmed
This retrospective review of the Sunnybrook Health Science Centre experience between January 1 , 1986 , and June 1 , 1988 , identified 153
polytrauma patients with a significant
head injury . -
pubmed
The 88
patients treated operatively had 12 complications : one
peroneal nerve palsy ; five cases of
sepsis ( three in open
fractures and all resolving with removal of fixation devices ) ; three
malunions ; and three cases of delayed union . -
pubmed
One
patient had
urinary retention . -
pubmed
The ageing spontaneously
hypertensive rat as a model of the transition from stable compensated
hypertrophy to
heart failure . -
pubmed
Spontaneously
hypertensive rats ( SHR ) of advanced age exhibit depressed myocardial contractile function and
ventricular fibrosis , as stable compensated
hypertrophy progresses to
heart failure . -
pubmed
Studies of papillary muscles from SHR with failing hearts ( SHR - F ) , SHR without failure ( SHR - NF ) , and age - matched Wistar Kyoto ( WKY )
rats allowed examination of changes in the mechanical properties of myocardium during the transition to
heart failure . -
pubmed
We cloned genes the expression of which is induced in the
Mongolian gerbil (
Meriones unguiculatus ) hippocampus after transient
forebrain ischemia by a differential display technique . -
pubmed
To determine the effectiveness of posterior H - frame instrumentation for the surgical treatment of
idiopathic scoliosis , 36
patients were studied . -
pubmed
Pseudoarthrosis developed in one
patient and imbalance in two
patients . -
pubmed
When compared to
patients treated with supraglottic laryngectomy alone , irradiated
patients had a significantly higher incidence of lifelong gastrostomy dependency ( 35 % versus 0 % ; p = .03 ) and acute
upper airway obstruction ( 29 % versus 0 % ; p = .05 ) . -
pubmed
There was a trend toward greater tracheotomy dependency ( 24 % versus 0 % ) , aspiration
pneumonia ( 35 % versus 9 % ) , and delayed independent swallowing ( 34.8 weeks versus 7.8 weeks ) in the
patients treated with combined therapy , but this difference was not significant . -
pubmed
This should be considered when planning treatment for
patients with
supraglottic carcinoma . -
pubmed
Among the volunteers , 73 % knew someone who may have had
AIDS or knew someone who was at risk for acquiring
HIV . -
pubmed
Severely burned
patients often present a
hypercoagulability situation . -
pubmed
Forty - three
patients were studied on the first and seventh day after
burn for
hypercoagulability and fibrinolysis parameters . -
pubmed
Severely burned
patients show a state of transient
disseminated intravascular coagulation , related to the development of organ failure and outcome . -
pubmed
METHODS : Over the last 36 months , seven
infants had a pleuroperitoneal shunt placed for the management of refractory
chylothorax . -
pubmed
RESULTS : All seven
patients had excellent results with the elimination of the
chylothorax and resolution of symptoms . -
pubmed
Patient survival rate was five of seven ( 71 % ) with one infant dying of progressive
pulmonary disease and one infant dying from
viral sepsis ; both had functioning shunts . -
pubmed
One
patient remains ventilator dependent secondary to
chronic lung disease from
prematurity . -
pubmed
These
strains were previously identified as virulent ( induce
diarrhea ) or attenuated ( no
diarrhea ) in a gnotobiotic
pig model of
rotavirus infection [ Bohl et al . -
pubmed
METHODS : For that purpose , a total of 30 chronic alcoholic
patients , 10 without
liver disease (
AWLD group ) and 20 diagnosed with
alcoholic liver cirrhosis (
ALC ) were studied . -
pubmed
Pregnancy aggravates
proteinuria in subclinical
glomerulonephritis in the
rat . -
pubmed
Because subclinical
renal disease may be aggravated during pregnancy -- as reflected in the occurrence of
proteinuria , for example -- we investigated whether a subclinical
glomerulonephritis (
SG ) in the non - pregnant
rat (
passive Heymann nephritis ) , a condition without
proteinuria , is aggravated when the
animals become pregnant and , if so , whether this is associated with a glomerular inflammatory reaction . -
pubmed
SG was induced in non - pregnant
rats 8 days before pregnancy . -
pubmed
Experiment 1 revealed that non - pregnant
rats with SG did not exhibit
proteinuria . -
pubmed
However , after the
rats became pregnant , a significant
proteinuria occurred , without an increase in
systolic blood pressure . -
pubmed
Experiment 2 revealed that the
GFR did not increase in pregnant
rats with SG , while experiment 3 showed that only pregnant
animals exhibited a significant
glomerular inflammation ; this
glomerular inflammation was characterized by intraglomerular influx of polymorphonuclear cells and monocytes . -
pubmed
Vaccination with DNA may provide a viable alternative or may be used in conjunction with protein - based subunit vaccines to maximize the efficacy of a
human malaria vaccine that includes immunogenic regions of the SERA protein . -
pubmed
All
patients underwent surgical re - exploration 3 - 4 days after immunoscintigraphy ; the presence of
tumour in the area of immunoscintigraphic uptake was evaluated in the biopsied material . -
pubmed
A knock - out
mouse for
Canavan disease is being genetically engineered in our laboratory . -
pubmed
Entacapone and
selegiline with
L - dopa in
patients with
Parkinson ' s disease : an interaction study . -
pubmed
We studied clinical response , tolerability , haemodynamics and cardiac rhythm in 16
PD patients with end - of - dose - type motor fluctuations . -
pubmed
One
patient already had symptomatic
orthostatism before experimental treatments ( control ) . -
pubmed
In two other
patients orthostatism emerged after the introduction of
selegiline , and in one after every experimental treatment . -
pubmed
One
patient treated with
entacapone+
selegiline discontinued the study due to
dizziness and
insomnia . -
pubmed
For that reason ,
xenon should be avoided in
patients with increased cerebral pressure or
cerebral perfusion disorders . -
pubmed
Voacanga africana is used in Cameroonian ethnomedicine for the treatment of
peptic ulcers . -
pubmed
Treatment failure and
death occurred in one
patient ( 1.9 % ) . -
pubmed
Three
patients ( 5.7 % ) experienced
relapses . -
pubmed
There was a significant difference in total effective treatment time between
patients with and without
relapses ( 8.3 + /- 1.1 months vs 11.1 + /- 2.1 months ; p & lt ; 0.02 ) . -
pubmed
A prospective study with different treatment durations is needed to determine the optimal treatment regimen for
patients with
INHr - TB . -
pubmed
METHODS : Twenty six eyes ( 26
patients ) with
optic disk pit maculopathy were treated with macular buckling procedure and evaluated with optical coherence tomography . -
pubmed
In this investigation , 28 tendons ( 21
patients ) with a painful nodule located at the 2 - 6 cm level in the tendon , and 20 normal (
pain - free ) tendons , were examined with grey - scale ultrasonography combined with colour Doppler examination . -
pubmed
Patients with a
mediastinal tumor , neural or rhabdomyosarcomatous differentiation and distant
metastases have the poorest prognosis . -
pubmed
The author had elaborated the concept , claiming that the
microangiopathy stage reflects the
diabetes mellitus stage , basing on the sixteen - year experience of examination and treatment of 1100
patients with
diabetic foot . -
pubmed
[ Experimental portal
hypertensive colopathy in
rats with
liver cirrhosis ] . -
pubmed
To elucidate the morphological feature of
portal hypertensive colopathy (
PHC ) , the macroscopic and microscopic vascular alterations of colonic mucosa was observed in
rats with
thioacetamide - induced
liver cirrhosis . -
pubmed
Histologic study revealed an increased in the number of the cross sections of venous vessels containing the colored lactices in the lamina propria mucosa(LP ) , lamina submucosal(SM ) and muscularis propria(MP ) in the
cirrhotic rats . -
pubmed
Stereoscopic results of the vascular cast obtained from the
cirrhotic rats showed the presence of two characteristic vascular sings , i.e. -
pubmed
In the clinical study , 38
patients with
liver cirrhosis and 40 normal control received colonoscopic examinations . -
pubmed
The
vascular lesions similar to WT and VE were seen in 78.9 % and 65.8 % of cirrhotic
patients , compared to 10.0 % and 7.5 % in the control . -
pubmed
Since the
cirrhotic rats used the present study were administered
thioacetamide for only 12 weeks , it was suggested that PHC could occurred even in early stage of
liver cirrhosis with mild portal
hypertension . -
pubmed
DESIGN : Awakenings were performed from SOREM ( REM at the onset of daytime naps and nighttime sleep ) and nighttime emergent ( ascending ) REM in 15
patients with
narcolepsy and from nighttime REM in 9 normal healthy
participants . -
pubmed
PARTICIPANTS : Fifteen
patients with
narcolepsy , aged 17 to 70 years ( mean = 45.3 ) and 9 normal healthy subjects , aged 31 to 60 years ( mean = 43.0 ) . -
pubmed
CONCLUSION : The REM sleep of
patients with
narcolepsy affords a unique opportunity to study emotion and to analyze its psychophysiology . -
pubmed
Adult worms were also found in the middle ears of 2
cats showing purulent
otitis . -
pubmed
[ Effects of homologous and heterologous
tumors on the growth and more especially the osseous development of young
animals ] . -
pubmed
Abnormalities of acetate metabolism in
adrenal insufficiency in
man . -
pubmed
OBJECTIVE : In this study
anxiety and
depressive disorders were evaluated in
patients admitted to an emergency department ( ED ) or to a medical department ( MD ) . -
pubmed
The widespread use of eradication therapy for
Helicobacter pylori has lead to an increase in antibiotic - resistant
strains and the problem of retreatment in cases of eradication failure . -
pubmed
The problem of
schistosomiasis in Egypt has been complicated in recent years by the introduction of
Biomphalaria glabrata , which has been reported to hybridize with
B. - pubmed
A 61 - year - old
female presented with a sudden onset of generalized
tonic -- clonic convulsion . -
pubmed
The
volunteers were given 0.55 g ( 20 % )
ethanol / kg
body weight as single dose about 4 hours after their breakfast meal , and on another occasion , 0.25 g
fructose / kg
body weight was used to sober the intoxicating effect produced by 0.55 g ( 20 % )
ethanol / kg
body weight . -
pubmed
Contact allergy to
cinnamal in a
patient with
oral lichen planus . -
pubmed
For & gt;15 generations , CD1
mice have been selectively and bidirectionally bred for either high - anxiety - related behavior ( HAB - M ) or
low - anxiety - related behavior ( LAB - M ) on the elevated plus - maze . -
pubmed
Furthermore , in both the forced - swim and tail - suspension tests , LAB - M
animals showed lower scores of immobility than did HAB - M and NAB - M
animals , indicative of a reduced
depression - like behavior . -
pubmed
BACKGROUND : Vagus nerve stimulation ( VNS ) had antidepressant effects in an initial open , acute phase pilot study of 59
participants in a treatment - resistant
major depressive episode (
MDE ) . -
pubmed
CONCLUSION : These results suggest that
patients with chronic or recurrent , treatment - resistant
depression may show long - term benefit when treated with VNS . -
pubmed
BACKGROUND AND OBJECTIVES : The relationship between somatic and psychiatric comorbidity in
patients with
somatic diseases and diverse outcome variables like mortality , costs , and duration of treatment is often examined and confirmed . -
pubmed
A previously published missense allele I515 T was found in the heterozygous state in an
individual who was observed to be temperature sensitive for the
auditory neuropathy phenotype . -
pubmed
SAMPLE POPULATION : Samples of TBLF obtained from 11 calves with clinical signs of
respiratory tract disease and growth of
P multocida and
Mycoplasma spp during culture of TBLF and samples of TBLF from 6 clinically normal calves with no bacterial growth during culture of TBLF . -
pubmed
BACKGROUND :
Respiratory syncytial virus (
RSV ) is associated with
wheezing illness , and
infections can occur repeatedly throughout life . -
pubmed
These processes may be involved in decreasing T cell antiviral immune responses to
RSV and in
RSV - associated
wheezing . -
pubmed
METHODS : One hundred and eighteen
patients ( 120 wrists ) who had been managed with the placement of an external fixation device for the treatment of a displaced , unstable , distal radial
fracture were randomized into one of three treatment groups : ( 1 ) weekly dry dressing changes without pin - site care ; ( 2 ) daily pin - site care with a solution of one - half normal saline solution and one - half
hydrogen peroxide ; and ( 3 ) treatment with the placement of
chlorhexidine - impregnated discs ( Biopatch ) around the pins , with weekly changes of the discs by the treating surgeon . -
pubmed
The
patients were evaluated with regard to ( 1 )
erythema , ( 2 )
cellulitis , ( 3 ) drainage , ( 4 ) clinical or radiographic evidence of
pin - loosening , ( 5 ) the need for antibiotics , and ( 6 ) the need for pin removal before
fracture - healing due to
infection . -
pubmed
Twenty - three
patients ( 19 % ) had a complication related to the pin track , with twelve of these
patients requiring oral antibiotics for the treatment of a
pin - track infection . -
pubmed
Spinal cord injury - induced plasticity in the
mouse -- the crossed phrenic phenomenon . -
pubmed
Therefore , we explored whether it was possible to demonstrate the
CPP in
mice , a
species amenable to a molecular genetic approach . -
pubmed
Interestingly , our data also suggest that in the
mouse latent fibers in the ventral funiculus ipsilateral to an anatomically incomplete hemisection may also play a role in the
CPP . -
pubmed
This is the first study to demonstrate the
CPP in
mice . -
pubmed
Simkania negevensis and
pneumonia in children . -
pubmed
We herein report a first case of an
infant with
fetal warfarin syndrome in Thailand . -
pubmed
The
patient eventually died from
respiratory failure at 6 months of age . -
pubmed
Fasting
glucose is not useful in identifying
obese white
children with
impaired glucose tolerance . -
pubmed
Animal models confirm that cell - mediated changes always follow structural failure caused by
trauma . -
pubmed
For the treatment of
pain and
irritation relief ( 21
patients , 22 eyes ) , all
patients had complete or partial relief . -
pubmed
We present two
patients with reversible
neurologic deficits after carotid artery stenting . -
pubmed
There was no
white matter edema or
intracerebral hemorrhage in either
patient . -
pubmed
Cephalic
ganglia appear smaller and disconnected in
1 - azakenpaullone - treated
animals , whereas visual axons are ectopically projected , and the pharynx does not regenerate properly . -
pubmed
The functional impact of early impairment was investigated by evaluating performance of everyday actions in older
adults with
mild AD ( n = 15 ) as compared with healthy age - matched controls ( n = 16 ) . -
pubmed
The ability to form biofilm is seen as an increasingly important colonization strategy among both pathogenic and environmental
Klebsiella pneumoniae strains . -
pubmed
glucose is impaired in
patients with
type 2 diabetes mellitus compared with healthy
individuals . -
pubmed
Cardiopulmonary resuscitation feedback and debriefing may serve as a powerful tool to improve rescuer training and care for
cardiac arrest patients . -
pubmed
Fetal and neonatal
nicotine exposure in
Wistar rats causes progressive pancreatic
mitochondrial damage and beta cell dysfunction . -
pubmed
However , fetal and neonatal
nicotine exposure in
rats causes mitochondrial - mediated beta cell apoptosis at weaning , and adult - onset
dysglycemia , which we hypothesize is related to progressive
mitochondrial dysfunction in the pancreas . -
pubmed
Importantly the appearance of these structural defects in
nicotine - exposed
animals preceded the onset of
glucose intolerance . -
pubmed
Taken together , these data suggest that maternal
nicotine use during pregnancy results in postnatal
mitochondrial dysfunction that may explain , in part , the
dysglycemia observed in the offspring from this
animal model . -
pubmed
Our aim was to find out whether rhAPC dampens OA - induced
ALI in
sheep . -
pubmed
The
axonal lesion of TMBP - recipient
mice resulted in lesion - specific recruitment of large numbers of T cells in contrast to very limited T - cell infiltration in TOVA - recipient and -naive perforant pathway - deafferented
mice . -
pubmed
METHODS : 14
men and 12
women aged 23 to 38 ( mean , 27 ) years with lateral
ankle instability underwent the Brostrom procedure with a modified incision to repair both the anterior talofibular and calcaneofibular ligaments , without endangering the sural or superficial peroneal nerves . -
pubmed
There was no apparent
tissue toxicity in the
murine peritoneum and the gel caused no adhesions . -
pubmed
Neuronal migration disorders are often identified in
patients with
epilepsy refractory to medical treatment . -
pubmed
The conditional mutant
mice were viable , but exhibited complex
neurological deficits including
seizures ,
tremors , and
growth retardation . -
pubmed
Metronidazole resistance of feline
Tritrichomonas foetus is presumed because of common treatment failure , and
tinidazole does not consistently eradicate
infection . -
pubmed
Single T factors predict survival of
patients with resected stage - IIB
non - small - cell lung cancers . -
pubmed
OBSERVATIONS : We discuss the mechanisms of oncogenicity , including genetic , environmental , and iatrogenic factors , in 2
patients with
HHD ,
multiple primary melanomas , and other
cancers . -
pubmed
Patient 1 had a
mucoepidermoid carcinoma of the parotid gland . -
pubmed
CONCLUSIONS : The cause of the
cancers in these 2
patients is likely multifactorial . -
pubmed
As our understanding of the molecular alterations driving
human cancer increases , there is an opportunity to direct the clinical application of
cancer therapeutics with improved accuracy . -
pubmed
Detection of circulating
tumor cells in metastatic
breast cancer patients . -
pubmed
OBJECTIVE : The objective of this study was the detection of circulating
tumor cells ( CTCs ) in metastatic
breast cancer patients . -
pubmed
Twenty eight
patients with metastatic
breast cancer were enrolled in the study and the control group consisted of 19 clinically healthy
women . -
pubmed
RESULTS : The positivity for
CTCs was found in 20 ( 50.0 % )
patients with metastatic
breast cancer patients , while in 6 ( 31.6 % ) healthy controls false positive circulating epithelial - like cells were detected . -
pubmed
Sarcocystis calchasi - associated
neurologic disease in a domestic pigeon in North America . -
pubmed
Tissue
cysts of a protozoan parasite were present in the skeletal muscle of a domestic
pigeon (
Columba livia f. domestica ) with
neurologic disease in Minnesota , USA . -
pubmed
The
animal had a severe
granulomatous meningoencephalitis . -
pubmed
A 72 - year - old
man was admitted to our hospital because of
dysphagia , and endoscopy showed a
tumor in the esophagus . -
pubmed
67 - year old
man in a good physical condition was admitted to the Clinic to diagnose mediastinal
tumor which was noticed on chest radiogram . -
pubmed
METHODS : This was a population - based cohort study of
patients who underwent gastrectomy for
peptic ulcer disease between 1964 and 2008 in Sweden . -
pubmed
Mechanisms of
endothelial dysfunction in resistance arteries from
patients with
end - stage renal disease . -
pubmed
Subcutaneous resistance arteries from 35
end - stage renal disease (
ESRD )
patients and 28 matched controls were studied ex - vivo . -
pubmed
Spores from two distinct colony types of the
strain Bacillus subtilis PB6 substantiate anti - inflammatory probiotic effects in
mice . -
pubmed
METHODS : The immunomodulatory potential of
strain PB6 was first characterized in vitro on
human immunocompetent cells for both the commercial spore powder ( Anaban ) and two phenotypic variants of the vegetative form . -
pubmed
Assessment of the in vivo anti - inflammatory capacity of the standard spore powder and a variant spore powder preparation was performed using a
mouse model of acute , TNBS - induced
colitis . -
pubmed
Hyperkalemia in predialysis
patients . -
pubmed
METHODS : We studied 32
ARDS patients with
shock despite fluid loading , who were randomized to receive TP ( 16
patients ) or
dopamine ( 16
patients ) . -
pubmed
Previous studies are limited by small numbers of
patients with specific forms of
diffuse lung disease . -
pubmed
RESULTS : There were 31
diffuse lung disease (
DLD ) , 57
cystic fibrosis (
CF ) , and 16
pulmonary vascular disease (
PVD )
patients included in our analysis . -
pubmed
Patients with
DLD had significantly higher pre - transplant morbidity including lower percent predicted of forced expiratory volume in first second ( P = 0.013 ) and more patients with
pulmonary hypertension ( P = 0.001 ) and
hypercapnia ( P = 0.031 ) . -
pubmed
CONCLUSION : Lung transplantation is as successful for
patients with end stage
diffuse lung disease as compared to other lung transplant candidates . -
pubmed
In addition , recent studies suggest that it may be useful in
critically ill patients . -
pubmed
There is significant difference in the transformation efficiency ( average number of days of hairy root induction ) and transformation frequency for all
strains of
A. - pubmed
However , the transformation frequencies of all five
strains were below 30 % , with
A. - pubmed
Percutaneous aortic valve implantation is an emergent technique alternative to surgical aortic valve replacement in high risk
patients with
aortic stenosis . -
pubmed
Periods of
nicotine withdrawal , in particular , may promote
panic in
individuals high in
anxiety sensitivity . -
pubmed
DESIGN : Open - label prospective cohort study of
patients with
GAVE refractory to APC . -
pubmed
PATIENTS : GAVE
patients with previous failed APC therapy ,
chronic anemia , and transfusion dependence . -
pubmed
RESULTS : Twenty - one
patients underwent at least 1 RFA session with ablation of
GAVE lesions . -
pubmed
Freund 's complete adjuvant was used to induce
AA in
rats . -
pubmed
Secondary paw swelling ,
polyarthritis index , index of immune organs and histopathological assessment were used to evaluate the effects of TAHP on AA in
rats . -
pubmed
We explored the ability of an oral milk
thistle extract formulation that was enriched with a water - soluble form of
silibinin complexed with the
amino - sugar meglumine to inhibit the growth of
non - small - cell lung carcinoma (
NSCLC )
mouse xenografts . -
pubmed
Bacterial contamination under fillings proved to be the main reason for
pulp inflammation thus emphasizing the importance of antibacterial properties of restorative materials . -
pubmed
Integrative ' omic ' approach towards understanding the nature of
human diseases . -
pubmed
The combination of improving technologies for molecular interrogation of global molecular alterations in
human diseases along with increases in computational capacity , have enabled unprecedented insight into
disease etiology , pathogenesis and have enabled new possibilities for biomarker development . -
pubmed
We therefore propose a novel positional integratomic approach toward studying ' omic ' information in
human disease . -
pubmed
HBV - LC
patients , especially the nonsurvival ones , manifested a profound decrease in the Treg / Th17 ratio , which was negatively correlated with Child - Pugh and model of
end - stage liver disease scores . -
pubmed
With improvements in medical and surgical care , overall survival of
patients with
SBS now exceeds 90 % . -
pubmed
Acute caloric restriction improves
glomerular filtration rate in
patients with morbid
obesity and
type 2 diabetes . -
pubmed
METHODS : Renal function , as measured by
glomerular filtration rate (
GFR ) , was evaluated in 14
patients with
type 2 diabetes mellitus , morbid
obesity and stage 2
chronic kidney disease before and after a 7 - day very low - calory diet ( VLCD ) . -
pubmed
Immunomodulatory effect of red
onion (
Allium cepa Linn ) scale extract on experimentally induced atypical
prostatic hyperplasia in
Wistar rats . -
pubmed
Atypical prostatic hyperplasia (
APH ) was induced in adult castrated
Wistar rats by both s.c . -
pubmed
The objective of this study was to review the efficacy of
frovatriptan vs. other
triptans , in the acute treatment of
migraine in subgroups of subjects classified according to gender ( men vs.
women ) through a pooled analysis of three individual randomized Italian studies . -
pubmed
414
patients suffering from
migraine with
or without aura were randomized to
frovatriptan 2.5 mg or
rizatriptan 10 mg ( study 1 ) ,
frovatriptan 2.5 mg or
zolmitriptan 2.5 mg ( study 2 ) ,
frovatriptan 2.5 mg or
almotriptan 12.5 mg ( study 3 ) . -
pubmed
After treating 1 - 3 episodes of
migraine in no more than 3 months with the first treatment ,
patients switched to the other treatment for the next 3 months . -
pubmed
In this analysis , traditional
migraine endpoints were compared between the 66
men and 280
women of the intent - to - treat population . -
pubmed
This may imply that
patients affected by a
neurodegenerative disease may benefit from treatment with selective inhibitors of innate immune activity . -
pubmed
TDF nephrotoxicity has been reported in both
HIV - infected and noninfected
patients . -
pubmed
Study design , follow - up , size of study population , treatment group ,
patient demographics , number of
patients exposed to
TDF or non -
TDF control , baseline characteristics , investigator - defined criteria for renal AEs , and number of discontinuations due to a presumed
renal AEs were extracted . -
pubmed
Arrested development of the dorsal column following neonatal
spinal cord injury in the
opossum ,
Monodelphis domestica . -
pubmed
We describe the morphological changes that occur in the dorsal column ( DC ) of the
grey short - tailed opossum ,
Monodelphis domestica , following
spinal cord injury at two early developmental ages . -
pubmed
This age - differential response , together with other facets of remodelling that occur after neonatal
spinal injury , might explain the locomotor adaptations and recovery observed in these
animals . -
pubmed
METHODS : Studies were conducted among hemodialysis (
HD )
patients with
ESRD due to
type 2 DM nephropathy ,
chronic glomerulonephritis , chronic
infective tubulointerstitial nephritis , and
hypertensive nephropathy as well as in healthy subjects . -
pubmed
RESULTS : No significant differences in a frequency distribution of tested polymorphisms were shown between
type 2 DM nephropathy patients and controls . -
pubmed
Different traits for
FHB resistance in
wheat were identified for common
wheat (
Triticum aestivum L. ) while the sources of FHB resistance in
durum wheat (
Triticum turgidum ssp . - pubmed
The objective of our research is to identify potential cell wall biochemical traits linked to
Fusariosis resistance to be transferred from a resistant common wheat to a susceptible
durum wheat line . -
pubmed
These include early involvement in the
patient 's care by a
wound prevention specialist and the incorporation of a
cholera cot design into the spinal transport board with a hole to completely offload the sacral tissue and permit the drainage of stool . -
pubmed
OBJECTIVE : The aim of our study was to investigate the ductus venosus doppler between 11 - 13 + 6 ( week - day ) in pregnant
women with
hemoglobinopaties and its relation with fetal outcomes . -
pubmed
MATERIAL AND METHODS : A total of 100 pregnant
women with
hemoglobinopathies and 100 healthy pregnant
women were included in our study . -
pubmed
This study examines the interactions between
Arabidopsis thaliana ( Arabidopsis ) and the pathogenic oomycete
Hyaloperonospora arabidopsidis ( Hpa ) by enhancer trapping to uncover novel plant genes involved in local
infection responses . -
pubmed
Biologically synthesised
silver nanoparticles from three diverse family of
plant extracts and their anticancer activity against
epidermoid A431 carcinoma . -
pubmed
METHODS : In this multicenter randomized controlled trial ,
cancer patients ( aged 8 - 18 years ) and their parents filled in questionnaires on HrQoL ,
depressive symptoms , behavioral problems , and self - esteem . -
pubmed
RESULTS :
SSAs have shown to help the symptomatic and biochemical improvement of
patients with
NETs and to exhibit a good safety profile . -
pubmed
MATERIALS AND METHODS : A retrospective cohort study was carried out on 619
patients with
papillary thyroid carcinoma between 2006 and 2012 ; we analyzed the sociodemographic , histological , prognostic and clinical characteristics . -
pubmed
This phase 3 , double - blind , placebo - controlled , randomised - withdrawal study evaluated the long - term maintenance of GXR efficacy in
children /
adolescents with
ADHD . -
pubmed
METHODS :
Children /
adolescents ( 6 - 17 years ) with
ADHD received open - label GXR ( 1 - 7 mg / day ) . -
pubmed
CONCLUSIONS :
Guanfacine hydrochloride demonstrated long - term maintenance of efficacy compared with placebo in
children /
adolescents with
ADHD . -
pubmed
diskImageR was used to examine the response of the
human fungal pathogen
Candida albicans to the antifungal drug
fluconazole across different
strain backgrounds and growth conditions . -
pubmed
A 73 - year - old
man was admitted with
stuporous mentality and left
hemiparesis after a motor - vehicle accident . -
pubmed
The
patient was treated conservatively at the intensive care unit in the acute stage to prevent extent of
stroke . -
pubmed
The Effects of Ultraviolet Eye Irradiation on Dextran
Sodium Sulfate - Induced
Ulcerative Colitis in
Mice . -
pubmed
This study evaluated change in gait , performance - based function , and self - reported function 1 year after TKA in
patients with symptomatic
knee osteoarthritis and how these aspects interrelate . -
pubmed
METHODS : A total of 28
patients ( 64 % female ) with
knee osteoarthritis , with a mean age of 66 ( + -7 ) years , and 25 age- and gender - matched controls participated in this prospective cohort study . -
pubmed
RESULTS : Kinetic gait deviations of both the operated and non - operated limb persisted in
patients with
knee osteoarthritis at 1 year after surgery , while kinematic gait patterns were comparable to controls . -
pubmed
Performance on the 5STS and KOOS scores in
patients with
knee osteoarthritis improved significantly 1 year after surgery ( effect size 0.5 - 1.5 ) , but did not reach the level of controls . -
pubmed
Ten
patients with
knee osteoarthritis ( 36 % ) exceeded the minimally detectable change on the 5STS . -
pubmed
METHODS : A total of 35
patients with
CKD and 25 healthy controls , were enrolled and we have evaluated inflammatory indexes , mineral metabolism , renal function , renal and cardiovascular ultrasonographic parameters . -
pubmed
RESULTS : Tricuspid anular plane systolic excursion ( TAPSE ) and estimated pulmonary artery
systolic pressure ( ePAPs ) showed a statistically significant difference between
CKD patients and healthy controls ( p<0.001 , p=0.05 ) . -
pubmed
Accurate assessment of right ventricular function is recommended in
patients with
CKD . -
pubmed
RRI and echocardiographic parameters can be an important instrument for the diagnosis , prognosis and therapeutic assessment of
cardio - renal syndrome in these
patients . -
pubmed
Ophthalmologic Outcomes of
Children Born Premature Without
ROP : Correlations With Gestational Age and Psychomotor Development . -
pubmed
PURPOSE : To study ophthalmological outcomes of premature
children with no
retinopathy of prematurity (
ROP ) and correlate with neurodevelopmental outcomes . -
pubmed
Children with any
motor disability tended to have worse vision . -
pubmed
The study includes 300
CAD patients , 100
FDRS , and 300 controls . -
pubmed
METHODS : We searched PubMed , EMBASE , and Cochrane search trials databases in English to identify studies comparing data on disease
recurrence in
PTC patients with mETE and those with no ETE . -
pubmed
The
recurrence rate in
patients with mETE is significantly higher when compared with those with no ETE ( risk ratio = 1.70 , 95 % confidence interval : 1.26 - 2.28 , I = 56 % ) . -
pubmed
CONCLUSION : mETE is a risk factor for poor prognosis in
patients with
PTC . -
pubmed
The frequency of
hyperparathyroidism was higher in the
children with
25 - OHD levels<18.0 ng / mL than in the
children with
25 - OHD levels>=18.0 ng / mL ( P<0.0001 ) . -
pubmed
Hypocalcemia was more prevalent in the
children with
25 - OHD levels<18.0 ng / mL than in the
children with
25 - OHD levels>=18.0 ng / mL ( P<0.0001 ) . -
pubmed
Surgical resection of
metastases represents an integral part of curative management in
patients with
testicular germ cell tumors (
GCT ) . -
pubmed
In clinical stage IIA / B , nsRPLND is indicated for
patients with marker - negative
metastases in whom cure rates of about 65 % can be achieved with surgery alone . -
pubmed
For NSGCT , pRTR is indicated in
patients with residual masses & gt;1 cm and negative or plateauing
tumor markers to resect persisting
teratoma or
vital cancer . -
pubmed
METHODS : We conducted an Asian multinational phase II study for
patients with
gastric GISTs & gt;=10 cm . -
pubmed
Embracing early discharge in
patients with lower
gastrointestinal bleeding . -
pubmed
Using
human prostate
tumor cell line
PC-3 as a model , an obvious induction of cell proliferation could be detected with a cell viability of 53.3 % , which was stronger than single cargo delivery , indicating the synergistic effect between these two components . -
pubmed
Prevalence of
Mycoplasma genitalium and other
sexually transmitted infections causing
urethritis among high - risk heterosexual male patients in Estonia . -
pubmed
BACKGROUND : We aimed to evaluate the prevalence of
sexually transmitted infections (
STI , including
Mycoplasma genitalium ,
Chlamydia trachomatis ,
Neisseria gonorrhoeae ,
Trichomonas vaginalis ) among high - risk heterosexual male patients and to clarify their potency to cause complaints and
inflammation . -
pubmed
gonorrhoeae has the highest potency to generate
urethral inflammation followed by
C. - pubmed
Profiling microRNA from Brain by Microarray in a Transgenic
Mouse Model of
Alzheimer ' s Disease . -
pubmed
Microarray analysis revealed 56 differentially expressed miRNAs in
AD mouse brain , which involved 39 miRNAs that were significantly upregulated and 19 that were downregulated at different ages . -
pubmed
Among those miRNAs , a total of 11 miRNAs , including miR-342 - 3p , miR-342 - 5p , miR-376c-3p , and miR-301b-3p , were not only conserved in
human but also predicted to have targets and signaling pathways closely related to the pathology of
AD . -
pubmed
INTRODUCTION : Optimal management of
malignant pleural effusion (
MPE ) is important in the care of
patients with advanced
cancer . -
pubmed
VATS - pleurectomy offered no survival advantage in a RCT of
mesothelioma patients . -
pubmed
It is essential to understand the pathophysiology of
cardiogenic shock and the possible deterioration of contractile function during high - risk PCI in order to select those
patients who could benefit from mechanical support thus choosing the most suitable device in every situation . -
pubmed
Aldehyde would irreversibly damage
bacterial cell wall and cytoplasmic membrane , resulting in decay and
death of
bacterial cells . -
pubmed
The study included 63
patients with
SSc in age from 16 to 67 years ( mean 42 years ) , among whom there were 11 % men and 89 % women . -
pubmed
As the control parameters studied in 52 healthy
people and 42
patients with limited
scleroderma . -
pubmed
SSc is accompanied by violations of BRP , which is manifested by increasing viscoelasticity module parameters in 8 % of
patients , and the surface tension in 66 % on the background of reducing surface elasticity level in 37 % , and the latters two parameters of interfacial tensiometry differ not only from those in healthy people as well as in patients with limited
scleroderma , and changes in the viscoelastic properties of the blood are prevalent in diffuse form of the disease compared to the limited form when there are dispersive correlation BRP with the severity of
skin lesions and extradermal manifestations of
SSc ( heart , lung ,
kidney disease ) , and the elastic and relaxation serum characteristics have predictive value , respectively , in the cases of limited and diffuse forms of the disease . -
pubmed
METHOD : The study included 120
patients hospitalized at a major level I regional
trauma center for the care of ( 1 ) closed long bone or calcaneus
fractures and/or ( 2 ) an
intraabdominal injury caused by
blunt force trauma and requiring surgical repair ( i.e. -
pubmed
Interestingly , the abundance of Akkermansia , a bacterial genus associated with loss of
body weight , was elevated dramatically in
mice subjected to a diet composed exclusively of meat . -
pubmed
This pathogen causes
vascular wilt symptoms and
death in both
E. - pubmed
The seven isolates could be differentiated from a
strain isolated from a diseased
E. - pubmed
The purpose of this study was to determine the function of female sexual hormones on the
gastric damage induced by I / R in male
rats . -
pubmed
Methods : Forty ( 40 )
Wistar rats were randomized into five groups : intact ,
ischemia- reperfusion ( IR ) , IR +
estradiol ( 1mg / kg ) , IR +
progesterone ( 16 mg / kg ) and IR + combination of
estradiol ( 1 mg / kg ) and
progesterone ( 16 mg/ kg ) . -
pubmed
Association between blood pressure variability and the short - term outcome in
patients with acute spontaneous
subarachnoid hemorrhage . -
pubmed
The association between the fluctuation in blood pressure ( BP ) and the early outcomes of
patients with
subarachnoid hemorrhage (
SAH ) remains unclear . -
pubmed
Our study aimed to evaluate the value of blood pressure variability ( BPV ) for predicting the short - term outcomes of
patients with acute spontaneous
SAH . -
pubmed
We collected data from 303
patients hospitalized for acute spontaneous
SAH . -
pubmed
In conclusion , systolic BPV within the first 24 h after admission was independently associated with the outcomes in
SAH patients ; the greater the variability was , the worse the outcome . -
pubmed
The importance of
estrogen for bone protection in experimental
hyperthyroidism in
human osteoblasts . -
pubmed
INTRODUCTION : Magnetic resonance imaging ( MRI ) is increasingly used in
patients with
rheumatoid arthritis (
RA ) to determine residual
inflammation after treatment and as a predictor of structural damage progression . -
pubmed
Early
neurological complications in
children with
classical galactosemia and p.gln188arg mutation . -
pubmed
BACKGROUND : Despite implementation of a controlled diet ,
children with
classical galactosemia (
CG ) may develop a variety of developmental and cognitive problems . -
pubmed
In this study , we examined the early developmental status of , as well as the neurological and neuroradiological findings for ,
children with
CG . -
pubmed
METHODS : We retrospectively evaluated 46
galactosemia patients who were followed between 2003 and 2017 . -
pubmed
There were 21
women and 21
men 21 - 70 years of age ( Avg 49 ) with operatively treated tibial plateau
fractures . -
pubmed
Across groups ,
patients with
bicondylar fractures tended to have higher VAS than those with
unicondylar fractures and to use more narcotics although neither was statistically significant . -
pubmed
INTERVENTION APPROACH : The integrated
HIV care services model consisted of 5 care coordination components : 1 ) case management , 2 ) HIV health care ( primary health care ) , 3 ) behavioral health care ( mental and
substance abuse screening and treatment ) , 4 ) adherence counseling ( a pharmacist - led intervention ) , and 5 ) social support services ( transportation , emergency food assistance , housing , and legal assistance ) . -
pubmed
Rats in the experimental group were injected with lipopolysaccharide ( LPS ) through the tail vein to prepare the model of
sepsis - induced
kidney injury , while those in the control group with the equal volume of normal saline . -
pubmed
Of 1304 consecutively admitted
patients with
type 2 diabetes , we enrolled 410
patients satisfying the criteria in this study . -
pubmed
OBJECTIVE : The aim of this systematic review was to evaluate the effect of therapies for
cognitive impairment on
patients ' perceived cognitive function in
breast cancer survivors with chemotherapy - related
cognitive impairment . -
pubmed
Aborted
myocardial infarction in
patients with
STEMI treated with mechanical reperfusion . -
pubmed
BACKGROUND :
Aborted myocardial infarction (
abMI ) is a type of
acute coronary syndrome in which
patients treated with reperfusion avoid the large burden of
necrosis . -
pubmed
METHODS : This is a retrospective registry of 1693 consecutive
patients with
STEMI treated with pPCI . -
pubmed
CONCLUSION :
Patients with
abMI have better short and long term outcomes . -
pubmed
Feasibility Case Study for Treating a
Patient with
Sensory Ataxia Following a
Stroke with Kinesthetic Illusion Induced by Visual Stimulation . -
pubmed
We examined the effects of KINVIS intervention in a
patient with
sensory ataxia . -
pubmed
CASE : The
patient was a 59 - year - old
man with a severe
proprioceptive deficit caused by left
thalamic hemorrhage . -
pubmed
Complement C5 inhibition in
patients with COVID-19 - a promising target ? -
pubmed
Sex differences in
patients with
cardiogenic shock requiring extracorporeal membrane oxygenation . -
pubmed
OBJECTIVE : Our study assesses differences between male and female
patients placed on venoarterial extracorporeal membrane oxygenation for
cardiogenic shock . -
pubmed
METHOD : We retrospectively analyzed 574 adult
patients placed on venoarterial extracorporeal membrane oxygenation for
cardiogenic shock at our institution between January 2007 and December 2018 . -
pubmed
In contrast to the situation in sub - Saharan Africa where
hepatitis B virus is incriminated as the most important etiologic factor of
HCC , it was found in the present study that
alcoholism was a very essential cause of
cirrhosis and thereby of
HCC . -
pubmed
Adult
cattle in a Queensland dairy herd with a history of
deaths from
lymphosarcoma were sampled regularly over a 4 year period for the identification of animals with persistent
lymphocytosis (
PL ) . -
pubmed
Two of these
animals had
lymphocytosis and two
lymphoblastic leukaemia . -
pubmed
The calf of one of the latter
cows developed
lymphoblastic leukaemia and
lymphosarcoma by the time it was 6 months of age . -
pubmed
Although histological evidence of
lymphosarcoma was lacking in a number of clinically normal
animals with
lymphocytosis , haematological investigation identified a group of
animals within the herd that may develop
lymphosarcoma . -
pubmed
In an experimental system , newborn
rats were totally protected against viral leukemogenesis by prenatal immunization of mothers with either live or inactivated
leukemia virus . -
pubmed
Although all had a satisfactory PaO2 ( mean , 49 mm Hg ) postoperatively , the
PGE1 - nonresponsive
patient experienced serious intraoperative
bradycardia ,
hypotension , and
acidosis in contrast to the
PGE1 - responsive group . -
pubmed
All had signs of acute
hepatitis at delivery , and
hepatitis B surface antigenemia persisted two to four weeks after delivery . -
pubmed
It is concluded that the salvage of
patients with para - aortic
metastasis will be small , but for those few long - term survivors , the benefit will be great . -
pubmed
Postoperative complications and survival after pancreatoduodenectomy in
patients aged over 70 years . -
pubmed
An analysis of
postoperative complications and survival was conducted in 31
patients undergoing pancreatoduodenectomy ( PD ) for
carcinoma of the pancreas or periampullary
carcinoma . -
pubmed
Definite
pancreatic leakage was found in one
patient in the over 70 group , and one case each of pancreatic , biliary , and gastric leakage were found in the under 70 group . -
pubmed
The cumulative survival rate of the
patients aged over 70 years with
carcinoma of the pancreas or periampullary
carcinoma did not differ significantly from the rate of those under 70 . -
pubmed
It was thus concluded that
PD achieves an adequate prognosis and survival in
patients over 70 years of age . -
pubmed
An analysis of the results of 9
patients with a
post - traumatic malalignment of the tibia , treated by an osteotomy and immediate bone grafting through a posterolateral approach is presented . -
pubmed
Viruses ( rhinovirus ,
parainfluenza virus , and
influenza virus ) and fungi ( Aspergillus ,
zygomycoses , Phaeohyphomycis , Pseudallescheria , and Hyalohyphomycis ) have also been reported to cause
ACAS . -
pubmed
50 de novo
patients with
Parkinson ' s disease were investigated in a retrospective study after
selegiline ( -)
deprenyl monotherapy and a combination of ( -)
deprenyl and
levodopa . -
pubmed
During the treatment period the distribution of age ( below 60 yr or above 60 yr ) among the Hoehn - Yahr stages was similar to that of the baseline period , while the clinical disability for the
patients starting with
hypokinesis meant a more severe state compared to the cases with
tremor . -
pubmed
Of 14
alcoholics , 7 had
alcoholic hepatitis alone , while the other 7 had
cirrhosis plus
alcoholic hepatitis . -
pubmed
Of 16 non - alcoholic
patients with
chronic viral infection , 6 had
chronic active hepatitis and 10
cirrhosis plus
chronic active hepatitis . -
pubmed
[
Ventricular arrhythmia and late potentials in
patients with
hypertrophic cardiomyopathy ] . -
pubmed
A prevalence of spontaneous
ventricular arrhythmias could be determined in 51
patients ; the results of 45
patients not taking antiarrhythmic drugs are presented here . -
pubmed
Absolute counts of
premature beats were low in most
patients , but important interindividual differences could be observed : M = 34 extrasystoles/24 h ( 0 - 4943 ) . -
pubmed
All
patients were asymptomatic during
tachycardia . -
pubmed
The influence of the maintenance medium ,
polyethylene glycol (
PEG ) , DEAE - dextran , and low temperature on reproduction of
influenza A , B , and
C viruses and their reassortants in diploid and
continuous cell cultures was determined . -
pubmed
Treatment of cells with
PEG solution increased the yield of
influenza B and C but not
A viruses . -
pubmed
However ,
influenza A virus strains proved to be capable of producing infectious progeny in
nonpermissive cell lines treated with
PEG . -
pubmed
Pentavalent
technetium-99 m ( V )- DMSA uptake in a
pheochromocytoma in a
patient with
Sipple ' s syndrome . -
pubmed
This case report describes
99mTc ( V )- dimercaptosuccinic acid (
DMSA ) accumulation in a
pheochromocytoma in a
patient with
Sipple ' s syndrome . -
pubmed
Phenotypic patterns of preneoplastic and
neoplastic hepatic lesions in
woodchucks infected with
woodchuck hepatitis virus . -
pubmed
Chronic infection of woodchucks with
woodchuck hepatitis virus (
WHV ) was associated with the development of
hepatitis , foci of altered hepatocytes and
hepatocellular adenomas and
carcinomas . -
pubmed
The phenotypic similarities and the close spatial relationship between the foci of altered hepatocytes , and the
hepatocellular adenomas and carcinomas in
WHV - infected
woodchucks , suggest that these lesions are preneoplastic . -
pubmed
Hyperglycemia produces a variety of effects , including osmotic diuresis and
cognitive dysfunction , which seriously impair the quality of life of the older
individual . -
pubmed
Fourteen
patients with benign symptomatic non - parasitic
cysts of the liver were either surgically treated , had
alcohol injected into the
cysts , underwent deroofing of the
cyst or in 5 , a cystectomy was done . -
pubmed
Alcohol was injected into 6
patients and there has been no
recurrence for as long as 5 years and 8 months after the treatment . -
pubmed
Liver dysfunction occurred in 3
patients given blood transfusion during the surgery and/or postoperative course , an elevated temperature ( over 39 degrees C ) occurred in one
patient . -
pubmed
Note on an association of
Clostridium novyi type A and
Clostridium sordellii with a case of
gas - gangrene in a Zebu
cow . -
pubmed
A case of
gas - gangrene myositis on a Zebu
cow with association of
Clostridium novyi type A and
Clostridium sordellii is described . -
pubmed
[ Use of
crystepin in combination with
obsidan in
patients with
diabetes mellitus with
arterial hypertension ] . -
pubmed
Examination included 70
patients with
diabetes mellitus in combination with
arterial hypertension of different origin ( II stage essential
hypertension and symptomatic
renal arterial hypertension ) . -
pubmed
The hemodynamic
hypotensive effects in these
patients due to the influence of the above therapy are uniform and depend on the form of attendant arterial
hypertension . -
pubmed
The
hypotensive effect of
crystepin used in combination with
obsidan was more pronounced in
patients with
diabetes and II stage essential
hypertension than that in those with
diabetes and
renal hypertension . -
pubmed
We used the
sheep lung lymph
fistula - endotoxin model of
ARDS to test this hypothesis . -
pubmed
Urinary glycosaminoglycans ,
sialic acid and lysosomal enzymes increase in nonalbuminuric
diabetic patients . -
pubmed
We prospectively followed 39 adults with concurrent primary
herpes simplex virus ( HSV ) infection ( 12 with
HSV type 1 and 27 with
HSV type 2 ) of the oropharynx and genitalia , caused by the same virus in each person , to evaluate the influence of viral type ( HSV-1 vs.
HSV-2 ) and site of
infection ( oropharyngeal vs. genital ) on the frequency of
recurrence . -
pubmed
Oral - labial
recurrences developed in 5 of 12
patients with
HSV-1 and 1 of 27 patients with
HSV-2 ( P less than 0.001 ) . -
pubmed
Conversely , genital
recurrences developed in 24 of 27
patients with
HSV-2 and 3 of 12 patients with
HSV-1 ( P less than 0.01 ) . -
pubmed
The mean rate of subsequent genital
recurrences ( due to
HSV-1 and
HSV-2 ) was 0.23 per month , whereas the mean rate of oral - labial
recurrences was only 0.04 per month ( P less than 0.001 ) . -
pubmed
We conclude that the likelihood of reactivation of
HSV infection differs between
HSV-1 and
HSV-2 infections and between the sacral and trigeminal anatomical sites . -
pubmed
The majority of
patients with recurrent
corneal erosion respond to conventional forms of therapy such as topical lubricants , patching , debridement , or bandage soft contact lenses . -
pubmed
Of 21 eyes in 18
patients treated in this manner , three eyes required retreatment of adjacent areas ; otherwise , there were no
recurrences in follow - up periods ranging from 5 months to 12 years . -
pubmed
Presence of
Rous sarcoma virus inside the mitochondria isolated by zonal and differential centrifugation from
Rous sarcoma cells . -
pubmed
The survival of surgically and medically treated
patients with left main - stem
coronary artery stenosis has been analysed in detail . -
pubmed
From 1978 to 1981 , 85
patients with
stenosis of the left main coronary artery greater than 50 % were divided into two groups ; 47 were treated surgically and 38 medically . -
pubmed
The opiate
quasiwithdrawal syndrome in
rhesus monkeys : comparison of
naloxone - precipitated withdrawal to effects of cholinergic agents . -
pubmed
Serum renotropic activity and renal growth in spontaneously
hypertensive rats . -
pubmed
[ Monitoring of plasma
theophylline levels in
asthmatic patients treated with
oxtriphylline ] . -
pubmed
In intact unanesthetized
rats , microinjection of a local anesthetic in the pontine tegmentum resulted in thermoregulatory responses , such as curling of the body , piloerection ,
tremor in facial muscles , and shivering . -
pubmed
The influence of three categories of anti -
cancer agents on competence development and on the binding of homologous DNA to cells have been studied in the
Bacillus subtilis transformation system . -
pubmed
In 7
patients with end - to - side portacaval shunts it was 94 + /- 18 % , in 3
patients with distal splenorenal shunts 57 + /- 11 % , and in 10
patients with
cirrhosis of the liver it varied between 15 % and 85 % . -
pubmed
The
embryotoxic potential of
ochratoxin A and
citrinin was studied after administering , either subgerminally or intraamniotically , single mounting doses of the mycotoxins to
chicken embryos on days 2 , 3 , and 4 . -
pubmed
It may be supposed that
citrinin produced together with
ochratoxin A in some
strains of
Penicillium viridicatum Westling does not potentiate the clear - cut
embryotoxic action of the latter mycotoxin . -
pubmed
Pyridoxal-5 '- phosphate determination by a sensitive micromethod in
human blood , urine and tissues ; its relation to
cystathioninuria in
neuroblastoma and
biliary atresia . -
pubmed
Nifedipine treatment for
pulmonary hypertension in a
patient with
systemic sclerosis . -
pubmed
Vulnerability of the hippocampus to
kainate excitotoxicity in the aged , mature and young adult
rat . -
pubmed
Sensitivity to
excitotoxic damage was assessed in young adult , mature and aged male
Sprague - Dawley rats . -
pubmed
A new antimycotic drug
lamisil ( Sandoz , Switzerland ) was given as pills to 35
patients with
pedal mycosis ( 23 of them suffered from
onychomycosis ) . -
pubmed
For 30 years we have followed the case of a euthyroid
patient who had a
goiter diagnosed at age 15 . -
pubmed
In a euthyroid
patient , the association of an elevated serum
PBI concentration ( with an abnormally large
butanol - insoluble
iodine fraction ) with a
diffuse goiter that became nodular and calcified may be unique . -
pubmed
Renovascular disease in
patients with
hypertension : detection with systolic and diastolic gating in three - dimensional , phase - contrast MR angiography . -
pubmed
Islet autotransplantation can prevent surgically induced
diabetes after total pancreatectomy in
adults ; however , the efficacy of this procedure has not been established in
children . -
pubmed
The authors report the case of a 12 - year - old
boy who underwent total pancreatectomy and islet autotransplantation for intractable
pain caused by
idiopathic chronic pancreatitis . -
pubmed
Postoperatively , the
patient had complete relief of
abdominal pain . -
pubmed
Human cytomegalovirus (
CMV ) can persist in many organs after primary
infection . -
pubmed
Not only is it suspected to cause morbidity during reactivation in
patients under immunosuppression , but it may also induce long - term latency by
chronic disease , e.g. -
pubmed
CMV - DNA could be assessed in 5 - 14 % of patients in the different stages of
myocarditis and in 22 % of
patients with
DCM . -
pubmed
Although two biopsies of the control group showed a positive result , studies by in - situ hybridization demonstrated that in patients with
heart muscle disease CMV persists in all cell types including myocytes , whereas in the controls it is only found in interstitial cells . -
pubmed
In a previous study , 30 pregnant
women suffering from
headaches were treated with physical therapy , relaxation training , and biofeedback . -
pubmed
The results indicate that the reductions in
headache activity were maintained at follow - up in the majority of the
women treated , with 67.5 % of the sample maintaining a significant decrease in
headache up to 1 year after giving birth . -
pubmed
Non - epileptic attack disorders in
children and adolescents : a single case study . -
pubmed
[ Prognostic factors and results of treating 42
patients with
nln - seminomatous germ cell tumor of the testis ] . -
pubmed
In 1984 - 1988 , 42
patients with
non - seminomatous germ - cell tumour of the testis were treated surgically in combination with chemotherapy . -
pubmed
The authors report an unusual case of bilateral short term acute
orchitis in a
patient with recurrent
polyserositis (
familial Mediterranean fever ) . -
pubmed
METHODS AND MATERIALS : Twenty - one
patients with histologically confirmed locally advanced inoperable
NSCLC ( Stage IIIA or IIIB ) were entered on study . -
pubmed
Because of severe
myelosuppression in the first two
patients ,
etoposide only was subsequently changed to 20 mg / m2 i.v . -
pubmed
Five
patients ( 25 % ) developed severe radiation
pneumonitis , leading to early closure of the study . -
pubmed
CONCLUSIONS : Combining daily protracted
cisplatin and
etoposide with concurrent thoracic irradiation in
patients with locally advanced unresectable
NSCLC yields a high overall response rate and a median survival that is at least comparable to other combined modality trials . -
pubmed
Pathophysiology of
Trypanosoma congolense infection in two breeds of
sheep , Scottish blackface and Finn Dorset . -
pubmed
The pathophysiology of
Trypanosoma congolense infection was studied in two breeds of
sheep , the Scottish Blackface ( SB ) and Finn Dorset ( FD ) , which were known from previous studies to differ significantly in their susceptibility to
haemonchosis , in which
anaemia is also the primary pathophysiological effect . -
pubmed
Wilms ' tumor gene expression in
human CD34 + hematopoietic progenitors during fetal development and early clonogenic growth . -
pubmed
PROCEDURE :
Body weight was recorded , and blood samples were collected from
dogs before , during , and after a 300 - mile race . -
pubmed
Body weight and estimated total exchangeable cation content in
dogs also decreased significantly during the race . -
pubmed
Rats were made chronically
epileptic by a period of continuous electrical stimulation of the hippocampus , which establishes an acute condition of self - sustained limbic
status epilepticus (
SSLSE ) . -
pubmed
This period of
SSLSE is followed by a development of chronic recurrent spontaneous limbic
seizures that are associated with chronic neuropathological changes reminiscent of those encountered in
human TLE . -
pubmed
Great apes ( Pongidae ) possess a chromosome similar to
human chromosome 21 ( HSA21 ) , whose
trisomy was described in both
chimpanzee and
orangutan . -
pubmed
This exposed the
human and Pongidae ancestry to trisomy 21 for a period of 30 - 50 million years , while , in other catarrhines , the equivalent of HSA21 was further involved in various translocations forming large chromosomes whose
aneuploidy , very probably incompatible with life , protected them against
trisomy 21 . -
pubmed
To study differentiation capacities of HCDCs , cells were attached to
hydroxyapatite /
tricalcium phosphate ceramic and transplanted subcutaneously into
immunodeficient mice . -
pubmed
A 78 - year - old
woman was admitted to our hospital on September 14 , 1992 , because of systemic
myalgia and
stiffness ,
joint pain , and
gait disturbance . -
pubmed
Recently , some
patients with
polymyalgia rheumatica have been reported to have anti - cardiolipin antibody in serum . -
pubmed
MATERIAL AND METHODS : From January 1982 to December 1995 , all
patients with a daily
alcohol intake in the previous year of at least 50 g per day and all
patients with
alcoholic cirrhosis whatever their drinking habits were studied . -
pubmed
Two thousand one hundred eight
patients had liver biopsy ; 37 % had histologically proven or probable
cirrhosis . -
pubmed
Forty one percent of the
patients without
cirrhosis who had liver biopsy already had
steatofibrosis and/or
acute alcoholic hepatitis . -
pubmed
DESIGN , SETTING , PARTICIPANTS : The performance measure , which assesses adherence to antipsychotic dose recommendations for acute
schizophrenia treatment , was calculated at hospital discharge for 116
patients with
schizophrenia who had participated in a 6 - month outcomes study . -
pubmed
Alarm pheromone enhances stress - induced
hyperthermia in
rats . -
pubmed
Experimentally naive male
Wistar rats were exposed to the test chambers containing alarm pheromones , which had been released by other
rats receiving foot
shocks in the same chamber beforehand . -
pubmed
Antioxidant micronutrients found in
fruits and
vegetables have been shown in numerous studies to be protective against
cancer . -
pubmed
Cryptococcus neoformans (
Cn ) is a soil fungus that causes life - threatening
meningitis in immunocompromised patients and is a facultative intracellular pathogen capable of replication inside macrophages . -
pubmed
Microscopy , fungal and amoebae killing assays , and phagocytosis assays revealed that Cn is phagocytosed by and replicates in
Acanthamoeba castellanii , which leads to
death of amoebae . -
pubmed
BACKGROUND : Percutaneous administration of
dihydrotestosterone (
DHT ) has been successful in promoting phallic growth in
infants and
children with
5 alpha - reductase deficiency raised as
males . -
pubmed
We investigated whether percutaneous administration of
DHT is similarly effective in
patients with
micropenis due to alternative diagnoses . -
pubmed
METHODS : Six
patients ( age range 1.9 - 8.3 years ) with
micropenis of variable etiology were studied prospectively . -
pubmed
CONCLUSION : Percutaneous administration of
DHT in a dose of 0.2 - 0.3 mg / kg once daily for a period of 3 - 4 months may be useful in the management of
patients with
testosterone biosynthetic defects , who have sufficient masculinization to warrant male sex assignment , or in
patients with
micropenis prior to reconstructive surgery . -
pubmed
Do antioxidants (
vitamins C , E ) improve outcomes in
patients with
coronary artery disease ? -
pubmed
Fluid extravasation during cardiopulmonary bypass in
piglets -- effects of
hypothermia and different cooling protocols . -
pubmed
Twenty
patients were randomly assigned to intra - operative end tidal PCO2 of 3.99 ( control ) or 5.99 kPa (
hypercapnia ) . -
pubmed
Mean ( SD ) subcutaneous tissue
oxygen tension was 8.39 ( 1.86 ) kPa in control and 11.84 ( 2.53 ) kPa
hypercapnia patients ( p = 0.014 ) . -
pubmed
Increases in subcutaneous tissue
oxygen partial pressure similar to those observed in
patients assigned to
hypercapnia are associated with substantial reductions in
wound infection risk . -
pubmed
METHODS AND MATERIALS : We report 10 - year biochemical
relapse - free survival ( BRFS ) on 232
patients presenting with
localized prostate cancer and consecutively treated with
iodine(125 ) ( I(125 ) ) or
palladium(103 ) (
Pd ( 103 ) ) brachytherapy and neoadjuvant external beam radiation therapy . -
pubmed
Selective immunohistochemical staining shows significant prognostic influence of lymphatic and blood vessels in
patients with
malignant melanoma . -
pubmed
Few data on the influence of lymphatic microvessel density ( LMVD ) on survival in
patients with
melanoma are available . -
pubmed
into
mice , angiogenesis and
tumor growth were inhibited . -
pubmed
The combination of
mitoxantrone - steroids improves clinical symptoms , namely by reducing
pain , but does not improve
patient survival . -
pubmed
Average
Hg concentrations in small
rainbow trout from all lakes , including Pinchi L. , were lower than dietary levels reported to cause
reproductive impairment in
common loons ( Gavia immer ) ; however ,
Hg levels in
small pikeminnow from Pinchi L. were sufficiently high to be of concern . -
pubmed
The risk for
Hg toxicity in the study area is greatest for animals that consume larger piscivorous fish such as larger
northern pikeminnow or
lake trout , which are known from previous studies to contain higher
Hg concentrations . -
pubmed
Hepatopulmonary syndrome in a
patient with
primary biliary cirrhosis . -
pubmed
A 54 - year - old Japanese
woman with
primary biliary cirrhosis (
PBC ) was admitted to our hospital due to
hepatic coma and refractory
pleural effusion . -
pubmed
Five RAPD - types with similar ITS sequences and phenotype were related to the ex - type
strain of
Penicillium pallidum ( generally given as a synonym of
G. - pubmed
MATERIALS AND METHODS : Sublethally irradiated
C57Bl / 6 mice were intravenously transplanted with rigorously purified lymphoid and myeloid progenitors from a congenic
mouse strain . -
pubmed
The patient was an 81 - year - old
woman with 2 separate
thymomas in the anterior mediastinum . -
pubmed
In Brazil ,
envenomation evoked by snakes ,
spiders and
scorpions are an important public health problem . -
pubmed
One
patient underwent an extracapsular
cataract extraction after the device was implanted , as a
senile cataract was then noted . -
pubmed
Neonatal herpes simplex virus (
HSV ) can be a devastating illness and may be difficult to diagnose in those cases without a typical
skin rash . -
pubmed
As a result , physicians often rely on
HSV polymerase chain reaction of cerebrospinal fluid to rule out
HSV encephalitis . -
pubmed
PURPOSE : To investigate the potential role of commercially available topical
fluoroquinolones in
diffuse lamellar keratitis (
DLK ) using New Zealand White
rabbit models . -
pubmed
The fungus ,
Histoplasma capsulatum , produces a persistent
infection . -
pubmed
In such situations ,
bacteremia and
infectious complications may be caused by translocation of either gastrointestinal
bacteria or its toxins as the result of
bacterial overgrowth ,
loss of intestinal epithelial integrity , or immunologic compromising of the host . -
pubmed
RECENT FINDINGS : Recent studies have shown that probiotics play a role in decreasing
postoperative complications in
patients undergoing major gastrointestinal operations . -
pubmed
[ Separation and purification of
phosphatidylcholine in
swine liver and its inhibition effect on proliferation of
rat hepatoma cells ] . -
pubmed
The effect of the PC with different concentrations on the proliferation of
rat hepatoma cell line (
CBRH-7919 ) was determined by microculture
tetrazolium (
MTT ) assays in vitro and was compared with that of
human leukemia cell line
K562 . -
pubmed
It suggested that
PC derived from
animal liver might function as a specific inhibitor for
hepatoma cells in a concentration dependent manner . -
pubmed
Cd - tolerant bacterial
strains of fluorescent pseudomonads , mostly belonging to
Pseudomonas monteillii , were isolated from termite mound soil (
Macrotermes subhyalinus , a litter - forager and fungus - growing termite ) , in a Sudanese shrubby savanna , Burkina Faso . -
pubmed
UNLABELLED : In a 5 - year study involving 119 postmenopausal
women ,
zoledronic acid 4 mg given once - yearly for 2 , 3 or 5 years was well tolerated with no evidence of
excessive bone turnover reduction or any safety signals . -
pubmed
The present study investigated the presence and prognostic role of
tumour necrosis (
TN ) and reactive perivascular T - cell infiltrate ( RPVI ) , defined as a rim of small reactive T - lymphocytes occurring alone or located between the vascular wall and large neoplastic cells , in
tumour samples from 100 immunocompetent
patients with
PCNSL . -
pubmed
World Health Organization histotypes of the
patients were : 96
diffuse large B - cell lymphomas , two
Burkitt - like lymphomas , one
anaplastic large T - cell lymphoma and one unclassified
B - cell lymphoma . -
pubmed
Patients with RPVI - positive lesions exhibited a significantly better overall survival ( OS ) than patients with RPVI - negative
lymphoma , particularly among patients treated with high - dose
methotrexate - based chemotherapy ( 3 - year OS : 59 + /- 14 % vs. 42 + /- 9 % , P = 0.02 ) . -
pubmed
To prevent the chronic carriage of
HBV in Saudi children ,
hepatitis B vaccine was added as the seventh immunogen in the expanded program on immunization ( EPI ) . -
pubmed
METHODS : We evaluated the frequency and type of neurological complications in
patients initially presenting with
ophthalmic herpes zoster at an ophthalmological department in a Danish university hospital , over a 7 - year period . -
pubmed
RESULTS : Of the 110 immunocompetent
patients who presented with initial
ophthalmic zoster , six ( 5.5 % ) suffered from neurological complications other than
post - herpetic neuralgia . -
pubmed
Four experienced isolated
cranial motor nerve palsies , one
patient had
meningitis with a favourable outcome and one
patient had severe
encephalitis with a poor clinical outcome . -
pubmed
The protecting effects and mechanisms of
Baicalin and
Octreotide on
heart injury in
rats with
SAP . -
pubmed
PURPOSE : To observe the protecting effects and mechanisms of
Baicalin and
Octreotide on
heart injury in
rats with severe acute
pancreatitis (
SAP ) . -
pubmed
CONCLUSION :
Baicalin and
Octreotide have protecting effects on
heart injury of
rats with
SAP . -
pubmed
Additionally , CAs and
cytotoxicity induced by
cyfluthrin were investigated in
rat (
Rattus norvegicus var . - pubmed
The frequency of
chromosome aberrations in bone - marrow cells of
rats treated with the test substance increased significantly ( P<0.05 ) for all doses ( 250 , 500 and 1000 mg / kg
body weight ) for the two treatment periods ( 12 and 24 h ) and the two administration routes , viz . -
pubmed
OBJECTIVE : To explore the effect of the pillar implant system in the management of
snoring and
OSAHS patients . -
pubmed
METHOD : All
patients are divided into three groups by PSG : mild to moderate
OSAHS , severe
OSAHS and
snoring . -
pubmed
AHI was reduced from 17.03 + /- 10.63 preoperatively to 11.17 + /- 9.52 postoperatively in 28
patients with mild to moderate
OSAHS and the total effective ratio was 67.9 % . -
pubmed
AHI was reduced from 62.93 + /- 9.21 preoperatively to 55.42 + /- 13.77 postoperatively in 6
patients with severe
OSAHS and the effective ratio was 16.7 % . -
pubmed
CONCLUSION : The pillar implant system had a significant effect on mild to moderate
OSAHS patients . -
pubmed
PATIENT(S ): A 35 - year - old
woman with no previous history of surgery had
endometriosis in the canal of Nuck excised incompletely via an open skin method . -
pubmed
The recovery of the brain from
anoxia after application of analeptic drugs ; electroencephalographic studies on
rabbits . -
pubmed
Discriminating virulence mechanisms among
Bacillus anthracis strains by using a
murine subcutaneous infection model . -
pubmed
In the
murine model of
pulmonary infection ,
B. - pubmed
infections using two different genetically complete ( pXO1(+ ) pXO2(+ ) ) strains of
B. - pubmed
These experiments demonstrate that the dominant virulence factors used to establish
infection by
B. - pubmed
METHODS : Twenty three
patients with CTO ,
stable angina and a positive exercise test result were included in the study . -
pubmed
Patients who remained persistently
depressed at 4 months had their clinical case notes reviewed to determine whether their low mood had been recognized or treated . -
pubmed
Depressed
patients had higher disease activity scores ( DAS28 ) at all time points , and
patients with persistent
depression had smaller reductions in DAS28 [ median ( interquartile range or IQR ) change DAS28 1.71 ( 0 - 2.6 ) vs 2.2 ( 1.5 - 3.2 ) ; P = 0.005 ] . -
pubmed
Only 57 % ( 13/23 )
patients with persistent
depression at 4 months had their
depression recognized or managed within the rheumatology clinic . -
pubmed
The opiate antagonist ,
naltrexone , has been used successfully in the treatment of
SIB in
individuals with
autism or
mental retardation . -
pubmed
Consistent with these results in the
rat , a review of the clinical use of
naltrexone in
SIB is also suggestive of a relative loss of efficacy at higher doses ( apparent therapeutic window ) . -
pubmed
Besides a gene in the
tetraploid wheat variety ' Altar ' that is identical to the hexaploid
wheat Lr10 , two additional , functional resistance alleles showing sequence diversity were identified by virus - induced gene silencing in
tetraploid wheat lines . -
pubmed
OBJECTIVES : To report the case of a 37 year - old
woman suffering from
endometriosis of the urinary tract , that presented with
lumbar and pelvic pain associated to cyclic recurrent
haematuria . -
pubmed
CONCLUSIONS : The frequency of
endometriosis in the urinary tract is relatively low and therefore ,
endometriosis presenting with
ureteral obstruction (
uretero - hydronephrosis ) has been rarely reported in the literature and should be part of the differential diagnosis in young
women , especially if symptoms are cyclic . -
pubmed
Intraventricular infusion of hyperosmolar dextran induces
hydrocephalus : a novel
animal model of
hydrocephalus . -
pubmed
None of the
animals with
hydrocephalus had
obstruction of the aqueduct or other parts of CSF pathways on MRI . -
pubmed
Apoptosis and cell proliferation correlated with
tumor grade in
patients with ampullary
carcinoma . -
pubmed
OBJECTIVE : To evaluate apoptosis and cell proliferation on cytologic specimens ( smears ) from endoscopic retrograde cholangiopancreatography in
patients with ampulary
carcinoma and to correlate that relationship with the grade of the
tumors . -
pubmed
STUDY DESIGN : Forty
patients ( 23
males and 17
females ) aged 45 - 81 who underwent endoscopic retrograde cholangiopancreatography were diagnosed by cytology as having ampullary
adenocarcinoma and the diagnoses were confirmed histologically after an operation . -
pubmed
CONCLUSION : Apoptosis ( cell
death ) and cell proliferation increase as the grade of the differentiation decreases in ampullary
carcinoma , suggesting a rapid turnover of the
tumor cells with lower grates of differentiation , and apoptosis may play an important role in the growth of the
tumors in
patients with
ampullary carcinomas . -
pubmed
Recent evidence suggests that illness due to
toxoplasmosis in immunocompetent persons may be related to
infection with an atypical genotype ; these
strains are
mouse virulent . -
pubmed
The isolate ( designated TgBbUS1 ) was
mouse virulent ;
mice inoculated with 1 oocyst or 1 tachyzoite died of
acute toxoplasmosis . -
pubmed
Issues of importance in these smaller trials include choice of agent , selection of appropriate trial participants , trial design , method of access to breast tissue in
women without
cancer , selection and monitoring of SEBs , and monitoring of
drug toxicity . -
pubmed
The various medicinal properties attributed to
Scutellaria baicalensis include anti - bacterial , anti - viral , anti - inflammatory and anti -
cancer effects . -
pubmed
Sex differentiation is influenced by a combination of hormonal , social and environmental factors and
teleost fishes exhibit many examples of
hermaphroditism . -
pubmed
This atypical clinical presentation of
STEC O104 : H4 infection might indicate new severe complications associated with this uncommon
strain , and highlights the importance of immediate interdisciplinary assessment of
STEC /
VTEC patients . -
pubmed
PATIENTS AND METHODS : Nineteen
children among whom 11
boys and 8
girls aged on average 5.3 - years old presented 7 recent and 12 late
hip dislocations . -
pubmed
An arthrotomy was performed in
children with a recent
dislocation . -
pubmed
Purinergic signaling inhibits
human acute myeloblastic leukemia cell proliferation , migration , and engraftment in
immunodeficient mice . -
pubmed
In the present study , we show that
ATP and
UTP have strikingly opposite effects on
human acute myeloblastic leukemia (
AML ) cells . -
pubmed
Recently , Ohnishi and Razzaque suggest that
phosphate toxicity accelerates the
mammalian aging process and that reducing the
phosphate burden can delay the aging ( FASEB J 24 , 3562 , 2010 ) . -
pubmed
Fifty - nine
patients with 71
fractures met criteria for study inclusion . -
pubmed
OBJECTIVE : The natural history of
patients with
metabolic syndrome (
MetS ) undergoing hemodialysis access placement is unknown . -
pubmed
RESULTS : Of the 187
patients who underwent hemodialysis access placement , 115 ( 61 % ) were identified to have
MetS. -
pubmed
A 33 - year - old
man with
chest pain ,
left upper lobe mass , pulmonary nodules , and bilateral
bullae . -
pubmed
Elastography , spleen size , and platelet count identify
portal hypertension in
patients with compensated
cirrhosis . -
pubmed
BACKGROUND & amp ; AIMS : Noninvasive methods are needed to identify clinically significant
portal hypertension (
CSPH ) and
esophageal varices (
EVs ) in
patients with compensated
cirrhosis . -
pubmed
We looked for markers of the presence of
CSPH and
EVs in
patients with
cirrhosis . -
pubmed
METHODS : We performed a cross - sectional study that included a training set of 117
patients with compensated
cirrhosis , confirmed by histology , from a tertiary referral center . -
pubmed
We assessed the ability of platelet count , spleen diameter , LS , and combinations of these factors ( ie , ratio of platelet count to spleen size , and LS x spleen size / platelet count [ LSPS ] ) to identify
patients with
CSPH and
EV . -
pubmed
RESULTS : LS was the best single noninvasive variable for identifying
patients with
CSPH ( area under the receiver operating characteristic , 0.883 ; 95 % confidence interval [ CI ] , 0.824 - 0.943 ; P & lt ; .0001 ) . -
pubmed
Analyses of the
varices risk score and LSPS were superior to all other noninvasive tests for identifying
patients with
EVs ( area under the receiver operating characteristic , 0.909 ; 95 % CI , 0.841 - 0.954 and 0.882 ; 95 % CI , 0.810 - 0.935 , respectively ) ; they correctly classified 85 % of patients in the training set and 75 % in the validation set . -
pubmed
Interspecies comparative analyses of gene expression profiles also showed that marginal
B - cell lymphoma and
diffuse large B - cell lymphoma in
dogs and
humans might represent a continuum of
disease with similar drivers . -
pubmed
Finally , we developed a benchtop diagnostic test based on expression of 4 genes that can robustly classify
canine lymphomas into one of these 3 subgroups , enabling a direct clinical application for our results . -
pubmed
BACKGROUND :
Erlotinib is registered for treatment of all
patients with advanced
non - small - cell lung cancer (
NSCLC ) . -
pubmed
Subjects in group A were exposed to 5.0 mg / kg
body weight of
caffeine dissolved in 200 mL of water on their first visit , whereas those in group B were exposed to 200 mL of water . -
pubmed
Chemical
burn caused by topical application of
garlic under occlusion . -
pubmed
Allium sativum (
garlic ) can cause an
irritant contact dermatitis , secondary to naturopathic practices . -
pubmed
We report an unusually severe case of chemical
burn following
garlic applied under occlusion . -
pubmed
Echocardiographic assessment of left atrial volume index in elderly
patients with
anterior wall myocardial infarction . -
pubmed
Enlarged left atrium ( LA ) predicts outcomes in
patients with
heart failure ,
atrial fibrillation and
stroke . -
pubmed
Therefore we studied left atrial volume index ( LAVi ) in elderly
patients with
left ventricle anterior infarction and correlated LAVi with left ventricle ejection fraction ( LVEF ) and transmitral Doppler flow . -
pubmed
Relationship between
ischemia /
reperfusion injury and acute rejection of allogeneic liver transplant in
rats . -
pubmed
OBJECTIVE : This study aimed to investigate the relationship between the severity of
ischemia / reperfusion ( I / R ) injury and the acute rejection ( AR ) of allogeneic liver transplants in
rats . -
pubmed
The
rats were humanely killed at 1 , 3 , 5 , and 7 days after transplantation or sham operation to determine the severity of I / R
injury , rejection classification , and hepatocyte apoptosis . -
pubmed
Further study and clinical trials are needed to confirm the benefits of systemic treatment in
gastric cancer patients with liver
metastasis . -
pubmed
Further , this activity will be evaluated both in vivo and in vitro in response to
infection with
Mycobacterium smegmatis to get an insight if there exists a co relation between the
Mycobacterium tuberculosis infection and khat chewing . -
pubmed
Feasibility and effectiveness of
posaconazole prophylaxis in combination with
micafungin bridging for
patients undergoing allogeneic stem cell transplantation : a 6 - yr analysis from the cologne cohort for
neutropenic patients . -
pubmed
Patients receiving
POS - MIC were less likely to develop a
pneumonic infiltrate ( RR 0.71 , 95 % CI 0.51 - 1.00 ) or possible
IFD ( RR 0.36 , 95 % 0.15 - 0.87 ) . -
pubmed
One of the most common complications of childhood
obesity is the
non - alcoholic fatty liver disease (
NAFLD ) , which is the most common form of
liver disease in
children . -
pubmed
The relatively small modifications in gene expression associated with chimerism is compatible with the high level of cooperation observed among different
strains of
D. - pubmed
Postpartum
osteoporosis and
vertebral fractures in two
patients treated with
enoxaparin during pregnancy . -
pubmed
Here , we report severe
PPO and multiple
vertebral compression fractures in two
patients treated with
enoxaparin -- low - molecular - weight heparin ( LMWH)--throughout their pregnancy . -
pubmed
A 34 - year - old
woman who has delivered her second baby 3 months ago presented with severe
low - back pain . -
pubmed
The other
patient was a 36 - year - old
woman diagnosed with
PPO and
vertebral fractures at the third week postpartum . -
pubmed
These findings suggest that
vertebral compression fractures and
PPO may be one of the causes of severe
back pain in postpartum
patients . -
pubmed
METHODS : Administrative databases , in four cross sections ( annually from 2007 to 2011 ) were consulted to analyse 149,015 individual records from
patients aged & gt;= 35 years with
type 2 diabetes mellitus . -
pubmed
The observation that approximately 15 % of
women with disseminated
breast cancer will develop symptomatic
brain metastases combined with treatment guidelines discouraging single - agent chemotherapeutic strategies facilitates the desire for novel strategies aimed at outright brain
metastasis prevention . -
pubmed
Here , we develop a novel method to quantitate early metastatic events ( arresting and extravasation ) in addition to traditional end time - point parameters such as
tumor burden and survival in an experimental
mouse model of brain
metastases of
breast cancer . -
pubmed
METHOD : Thirty - seven
OCD patients and 33 healthy comparison
subjects learned to avoid
shocks while undergoing a functional MRI scan . -
pubmed
RESULTS : Excessive habit formation in
OCD patients , which was associated with hyperactivation in the caudate , was observed . -
pubmed
CONCLUSIONS :
OCD patients exhibited excessive habits that were associated with hyperactivation in a key region implicated in the pathophysiology of
OCD , the caudate nucleus . -
pubmed
DCs isolated from
mice that had received resting but not activated ACs could transfer the suppression of
inflammation to recipient
mice . -
pubmed
Ten
children with
HPA with known mutations were recruited for validating the method . -
pubmed
Clinical outcomes , including adverse events , in 52 advanced
breast cancer patients treated with
eribulin chemotherapy after
taxane treatment ( TX ) were analyzed to confirm the effectiveness and safety of this treatment . -
pubmed
On the other hand , the number of
patients with
sensory peripheral neuropathy of Grade 1 or more was significantly more in the TX group than in the non - TX group . -
pubmed
In addition , sensory
peripheral neuropathy is a possible complication that can occur in advanced
breast cancer patients treated with
eribulin chemotherapy with
taxane treatment history . -
pubmed
BACKGROUND : Hexaploid
triticale could be either synthesized by crossing
tetraploid wheat with
rye , or developed by crossing hexaploid
wheat with a hexaploid
triticale or an octoploid
triticale . -
pubmed
CONCLUSION : This study confirms that whole D - genome chromosomes could be preferentially eliminated in the hybrid of common
wheat x
rye , " genome
shock " was accompanying the allopolyploidization of nascent triticales , and great morphologic divergence might result from the genetic variations . -
pubmed
Thus , the change of confluent
white matter lesions may be used as a surrogate marker in proof - of - concept trials with small
patient numbers needed to show treatment effects on lesion progression . -
pubmed
CASE PRESENTATION : We present a 29 year - old
woman with a rapid course of
hereditary diffuse leukodystrophy with spheroids . -
pubmed
The
nude mice model of
endometriosis was constructed and the endometrial cell nodule formation was observed . -
pubmed
MATERIAL AND METHODS : One hundred and fifty - four
patients ( age range : 28 - 69 ) with severe
chronic asthma ( study group ) and 141
patients with chronic mild disease ( control group ) diagnosed according to GINA criteria were included in the study . -
pubmed
An earlier onset of
asthma together with a greater number of exacerbations was noted in severe
asthmatics compared to
patients with mild disease . -
pubmed
More IDA
patients had complications after surgery ( 40.4 % vs. 27.7 % ; P less than 0.001 ) , such as nonabsorption ( 22.4 % vs. 16.5 % ; P less than 0.001 ) ; digestive ( 15.6 % vs. 10.2 % ; P less than 0.001 ) ; and
gastrojejunal ulcer ( 7.6 % vs. 2.0 % ; P less than 0.001 ) . -
pubmed
Male and female
mice from reciprocal consomic
strains originating from the C57BL/6ByJ and 129P3 / J
strains were bred and measured for
body weight , length , and adiposity . -
pubmed
Mechanistic studies in
mice and
humans have implicated formation of a reactive metabolite ,
mitochondrial dysfunction and oxidant stress as critical events in the pathophysiology of
APAP - induced liver cell
death . -
pubmed
It was recently suggested that
ATP released from
necrotic cells can directly cause cell
death in
mouse hepatocytes and in a
hepatoma cell line (
HepG2 ) . -
pubmed
Furthermore , addition of
ATP did not cause
mitochondrial dysfunction or enhance
APAP - induced
mitochondrial dysfunction in primary
murine hepatocytes , although
ATP did cause cell
death in
murine RAW macrophages . -
pubmed
CONCLUSIONS : It is unlikely that
ATP released from
necrotic cells can significantly affect cell
death in
human or
mouse liver during
APAP hepatotoxicity . -
pubmed
RELEVANCE FOR
PATIENTS : Understanding the mechanisms of
APAP - induced cell
injury is critical for identifying novel therapeutic targets to prevent
liver injury and
acute liver failure in
APAP overdose patients . -
pubmed
METHODS : BALB / c
mice were randomly assigned to five groups , and
ALF was induced in
mice by intraperitoneal injection of
D - GaIN ( 600 mg / kg ) and LPS ( 10 mug / kg ) . -
pubmed
neoaurum JC-12 / pMTac - ksdd was 5.94 g / L , increased about 22.2 % compared to the original
strain M. - pubmed
Correlation of
Stomatitis and
Cutaneous Toxicity With Clinical Outcome in
Patients With
Metastatic Renal - Cell Carcinoma Treated With
Everolimus . -
pubmed
PATIENTS AND METHODS : We retrospectively reviewed the clinical data of
patients with
mRCC treated with
everolimus in 2 Italian centers . -
pubmed
RESULTS : Seventy - nine
mRCC patients treated with
everolimus ( 57
male , 22
female ; median age 66 years ; range , 44 - 88 years ) were evaluated . -
pubmed
Effect of Descemet Membrane Endothelial Keratoplasty on Color Vision in
Patients With
Fuchs Dystrophy . -
pubmed
PURPOSE : To assess changes in color discernment after Descemet membrane endothelial keratoplasty ( DMEK ) in
patients with
Fuchs endothelial corneal dystrophy (
FECD ) . -
pubmed
METHODS : In this prospective , single - center study , the study group was composed of 26
patients with
FECD , aged 46 to 85 years , who underwent DMEK as a single surgical procedure ; 24 ( 92 % ) had pseudophakic and 2 ( 8 % ) had phakic eyes . -
pubmed
A control group of 14
subjects , aged 57 to 85 years , was tested 1 month after
cataract surgery . -
pubmed
CONCLUSIONS : Consistent with spontaneous comments from some
patients with
FECD that colors appear more vivid after DMEK , a comparison of pre- and postoperative color vision scores showed that color discernment usually improved after DMEK ( 81 % ) . -
pubmed
[ Acoustic analysis in
patients with unilateral
arytenoid dislocation and unilateral
vocal fold paralysis ] . -
pubmed
OBJECTIVE : To analysis the acoustic characteristics in
patients with unilateral
arytenoid dislocation and unilateral
vocal fold paralysis , and evaluate the application value of acoustic analysis technique in these two diseases . -
pubmed
METHOD : The voice signals of sustained vowel /a/ were measured using the software MDVP in 50 healthy
adults and 67
patients with unilateral
vocal cord movement disorders . -
pubmed
All
patients were divided into
arytenoid dislocation group ( 36 cases ) and
vocal fold paralysis group ( 31 cases ) through the laryngeal electromyography . -
pubmed
CONCLUSION : The acoustic parameters are effective parameters to measure the voice quality of
patients with unilateral
arytenoid dislocation and unilateral
vocal fold paralysis . -
pubmed
Experiments on isolated perfused
rat heart modeled 45 - min global
ischemia followed by 30 - min reperfusion . -
pubmed
RESULTS : The screening performance was assessed for the 156,122
children studied , of which 151,258 belonged to the group of not - at - risk children ; and 4864 to the group at risk of
hypoacusia . -
pubmed
METHODS : This technique was used in 6
patients with heavily calcified
craniopharyngiomas ( 2 recurrent ) who had presented with progressive
visual loss . -
pubmed
All of the
patients had transient
diabetes insipidus . -
pubmed
Two
patients who had preoperative
hypopituitarism required long - term postoperative hormonal replacement . -
pubmed
Viral proliferation and expression of
tumor - related gene in different
chicken embryo fibroblasts infected with different tumorigenic phenotypes of
avian leukosis virus subgroup J. -
pubmed
Subgroup J avian leukosis virus (
ALV - J ) causes a
neoplastic disease in infected
chickens . -
pubmed
The
ALV - J strain NX0101 , which was isolated from broiler breeders in 2001 , mainly induced formation of
myeloid cell tumors . -
pubmed
To identify the molecular pathological mechanism underlying changes in host susceptibility and
tumor classification induced by these two types of ALV - J strains ,
chicken embryo fibroblasts derived from
chickens with different genetic backgrounds (
broiler breeders and
laying hens ) and an immortalized
chicken embryo fibroblasts (
DF-1 ) were prepared and infected with
strain NX0101 or
HN10PY01 , respectively . -
pubmed
We therefore examined whether in the
murine model of
tuberculosis , the anti - inflammatory effects of
1,25 ( OH ) 2D3 would affect the outcome of M.
tuberculosis infection . -
pubmed
tuberculosis infected
mice led to a change in lung
granuloma architecture , characterized by a marked decrease in B cell lymphocytic aggregates . -
pubmed
Consistent with the altered
granulomas ,
1,25 ( OH ) 2D3 - treated
mice also exhibited significantly higher
bacterial burden in the lungs compared to the control group . -
pubmed
OSA patients scored significantly lower on 7 domains of SF-36 compared to the population . -
pubmed
PATIENTS : Nonintubated
patients without mechanical ventilation ( n = 90 ) presenting with
sepsis - induced
acute circulatory failure and considered for volume expansion . -
pubmed
After volume expansion , a relevant ( & gt;= 10 % )
stroke volume index increase was recorded in 56 %
patients . -
pubmed
CONCLUSIONS : The collapsibility index of the inferior vena cava during a deep standardized inspiration is a simple , noninvasive bedside predictor of fluid responsiveness in nonintubated
patients with
sepsis - related
acute circulatory failure . -
pubmed
Intravenous
methylprednisolone had a poor response and the
patient was submitted to ulnar nerve decompression , which confirmed
nerve abscess with purulent discharge during surgery . -
pubmed
As the
patient weighed more than 40 kg , treatment with a pediatric dose was considered insufficient and adult - dose
MDT was prescribed , with improvement of nerve
pain and function . -
pubmed
There is scant literature about the imaging findings of
nerve abscess in
leprosy patients . -
pubmed
Radiologists should suspect
leprosy in
patients with no other known causes of
neuropathy when detecting asymmetric nerve enlargement and
nerve abscess on ultrasound . -
pubmed
Outcomes of first line chemotherapy in
patients with
chronic lymphocytic leukemia . -
pubmed
Aim of this study was to determine the outcomes of
patients with
chronic lymphocytic leukemia treated with different available chemotherapeutic regimens . -
pubmed
METHODS : All
patients with diagnosis of
CLL from 2008 to 2013 were included . -
pubmed
OBJECTIVE : To assess the efficacy of active treatment targeted at underlying disease (
TTD)/potentially curative treatments versus palliative care ( PC ) in improving overall survival ( OS ) in terminally ill
patients . -
pubmed
Despite recent advances in curing
chronic hepatitis C (
CHC ) , the high economic burden to therapy , viral drug resistance , difficult to treat
hepatitis C virus (
HCV ) genotypes and patient groups are still of concern . -
pubmed
IDPP was synergistic in combination with FDA - approved
HCV drugs and inhibited pre - existing resistant
HCV strains induced by
today 's therapies . -
pubmed
Systematic Review of Safety and Cost - Effectiveness of
Venous Thromboembolism Prophylaxis Strategies in
Patients Undergoing Craniotomy for
Brain Tumor . -
pubmed
BACKGROUND : Studies have evaluated various strategies to prevent
venous thromboembolism (
VTE ) in neuro - oncology
patients , without consensus . -
pubmed
METHODS : A literature search was conducted for
VTE prophylaxis in
brain tumor patients . -
pubmed
CONCLUSION : Although
MP+
LMWH is frequently considered the optimal prophylaxis for
VTE risk reduction , our model suggests that
MP+UFH is the safest and most cost - effective measure to balance
VTE and
hemorrhage risks in
brain tumor patients at lower risk of
hemorrhage . -
pubmed
MP+
LMWH may be more effective for
patients at higher risk of
VTE . -
pubmed
Late pubertal growth spurt in a
girl with
growth hormone deficiency : Is Kaufmann therapy effective in a
girl with
short stature who responds poorly to growth hormone therapy and
estrogen - replacement therapy ? -
pubmed
A Japanese senior high school
girl aged 18 years and 5 months with
growth hormone deficiency was referred for
primary amenorrhea . -
pubmed
Failure of the vascular hypothesis of
multiple sclerosis in a
rat model of chronic
cerebrospinal venous insufficiency . -
pubmed
The present study was designed to validate this hypothesis using a
rat model of
CCSVI . -
pubmed
The
rats were followed clinically for eight months and neurological examination detected no
weakness or
paralysis in the operated
rats . -
pubmed
Transmission from
human to
human is one of its main characteristics in comparison with other fungi responsible for invasive
infections . -
pubmed
PCP is caused by genotypically distinct mixtures of organisms in more than 90 % of cases , reinforcing the hypothesis that there is constant inhalation of
P. - pubmed
MATERIAL AND METHODS We enrolled 240
patients with
BPPV from Beijing Chaoyang Hospital between July 2013 and July 2016 . -
pubmed
Although the level of SUA was lower in
BPPV patients , SUA was not an independent risk factor for
BPPV . -
pubmed
MATERIALS AND METHODS : We retrospectively identified 122
patients who presented to the emergency department from April 2011 through April 2016 with recent direct
trauma to the anterior segment of the eye . -
pubmed
This critically important sign predicted
anterior globe rupture in 39 of 47
patients ( odds ratio , 68.25 ; p & lt ; 0.0001 ) . -
pubmed
BACKGROUND :
Patients with
amnestic mild cognitive impairment (
aMCI ) have an increased risk of
dementia . -
pubmed
Therefore , predicting the
dementia conversion in these
patients is important . -
pubmed
OBJECTIVE : We aimed to develop a nomogram to predict
dementia conversion in
aMCI subjects using neuropsychological profiles . -
pubmed
METHODS : A total of 338
aMCI patients from two hospital - based cohorts were used in analysis . -
pubmed
All
patients were classified into 1 ) verbal , visual , or both , 2 ) early or late , and 3 ) single or multiple - domain aMCI according to the modality , severity of
memory dysfunction , and multiplicity of involved cognitive domains , respectively . -
pubmed
Patients were followed up , and conversion to
dementia within 3 years was defined as the primary outcome . -
pubmed
Here , we review the factors that might contribute to the low vaccine efficacy , including passive transfer of maternal rotavirus antibodies , rotavirus seasonality , oral
polio vaccine ( OPV ) administered concurrently , microbiome composition and concomitant enteric pathogens ,
malnutrition , environmental
enteropathy ,
HIV , and histo blood group antigens . -
pubmed
Feasibility of Concurrent Chemoradiation in
Patients treated for
Esophageal Carcinoma : A Single Institutional Experience . -
pubmed
Due to compromised nutritional status , radiation therapy in
esophageal cancer patients itself is a challenge and addition of concurrent chemotherapy leads to severe side effects even when standard dose regimens are used . -
pubmed
The tolerance of chemoradiation for
carcinoma esophagus in Indian
patients is still unclear . -
pubmed
This study is an effort to know feasibility of chemoradiation in
patients treated for
esophageal carcinoma in our hospital . -
pubmed
Feasibility of Concurrent Chemoradiation in
Patients treated for
Esophageal Carcinoma : A Single Institutional Experience . -
pubmed
Hepatitis E virus (
HEV ) is considered the main etiological agent that causes acute
hepatitis . -
pubmed
Posttraumatic Stress in
Children After
Injury : The Role of Acute
Pain and Opioid Medication Use . -
pubmed
OBJECTIVES : After
injury , many
children experience
posttraumatic stress symptoms (
PTSS ) that negatively impact recovery . -
pubmed
BACKGROUND : Recently transapical off - pump mitral valve repair with NeoChord implantation has been demonstrated to be safe and effective in
patients with
degenerative mitral regurgitation (
DMR ) . -
pubmed
METHODS : We retrospectively analyzed baseline and early postoperative 3 - dimensional transesophageal echocardiography of 66
patients who underwent NeoChord repair for isolated posterior leaflet
MV disease using semiautomatic off - line analysis software . -
pubmed
CONCLUSIONS : Transapical NeoChord repair produces important acute intraoperative changes in MV anatomy in
DMR patients . -
pubmed
Cardiac Stress and Inflammatory Markers as Predictors of
Heart Failure in
Patients With
Type 2 Diabetes : The ADVANCE Trial . -
pubmed
Two genetically different
porcine epidemic diarrhea virus (
PEDV )
strains have been identified in the USA : US prototype ( also called non - S INDEL ) and S INDEL PEDVs . -
pubmed
Complete genome sequence analyses indicated this
PEDV variant was genetically similar to US non - S INDEL
strain but had a continuous 600 - nt ( 200 - aa ) deletion in the N - terminal domain of the spike gene compared to non - S INDEL PEDVs . -
pubmed
METHODS : We retrospectively reviewed the charts of
patients who experienced subaxial
cervical facet injury within the Penn Health System between 1 June 2006 and 1 June 2016 to identify
patients with bilateral jumped / perched facets . -
pubmed
The objective of this study was to examine microvascular function in
women at high risk for
preeclampsia at mid - gestation . -
pubmed
Patients were recruited if they met eligibility criteria indicating high risk for
preeclampsia . -
pubmed
Serratia marcescens is an opportunistic
human pathogen causing various
nosocomial infections , most importantly
urinary tract infections (
UTIs ) . -
pubmed
Assessing taste and smell alterations in
cancer patients undergoing chemotherapy according to treatment . -
pubmed
RESULTS : Seventy - six percent
patients reported
taste disorders and 45 % smell changes . -
pubmed
Recent lines of evidence suggest that
dehydroepiandrosterone (
DHEA ) , a
19 - carbon steroid hormone classified as an adrenal
androgen , exerts a chondroprotective effect in
OA patients , and it has been proven to be an effective DMOAD candidate that slows
OA progression . -
pubmed
Encouragingly , the current data on
DHEA are promising and may prove that
DHEA - based treatment is efficacious for preventing and slowing
human OA progression . -
pubmed
People with
dementia had 52 % lower odds of receiving OAC compared to people without
dementia . -
pubmed
People with
dementia had higher
bleeding risk and poorer anticoagulation control when treated with
warfarin . -
pubmed
Allergen - specific sublingual immunotherapy is dose and duration dependent in a
murine allergic rhinitis model . -
pubmed
Results : The incidence rates of
atelectasis two hours after extubation on the first day of surgery were 22 ( 36.7 % ) , 20 ( 33.3 % ) and 10 ( 16.7 % )
patients in the control , PEEP8 and PEEP10 groups , respectively . -
pubmed
The incidence rates of
atelectasis on the third day after surgery were 39 ( 65 % ) , 36 ( 60 % ) and 21 ( 35 % )
patients in the control , PEEP8 and PEEP10 groups , respectively . -
pubmed
RESULTS : Among 10 604
T2DM patients included in this study , there were 3744 cases of
diabetic nephropathy(35.31 % ) . -
pubmed
The purpose of this study was to present the surgical outcome in
optic disc pit associated maculopathy in a
patient who was treated with vitrectomy , internal limiting membrane ( ILM ) peeling , barrage laser photocoagulation , and
silicone oil tamponade . -
pubmed
vitrectomy combined with posterior hyaloid and ILM peeling followed by
silicone oil tamponade , with additional laser photocoagulation , was successful for the treatment of
optic disc pit maculopathy in our
patient . -
pubmed
INTRODUCTION : To investigate the structural changes of the brain that correlate with physical
frailty and
cognitive impairments in
Parkinson ' s disease (
PD )
patients . -
pubmed
METHODS : Sixty - one
PD patients and 59 age- and sex - matched healthy controls were enrolled . -
pubmed
Exploratory group - wise comparisons of gray matter volume ( GMV ) in the
PD patients and controls were conducted . -
pubmed
Voxel - wise multiple linear regression analyses were conducted for physical
frailty - related and
cognitive impairment - related GMV changes in the
PD patients . -
pubmed
RESULTS : The
PD patients exhibited diffuse GMV reductions in comparison to the controls . -
pubmed
INTRODUCTION : There are limited data on outcomes of living donor liver transplantation ( LDLT ) for
patients with severe
alcoholic hepatitis . -
pubmed
The
patients with
alcoholic hepatitis were abstinent for a duration of 4 + - 1.8 months at the time of LDLT . -
pubmed
When
patients with
alcoholic hepatitis ( n = 39 ) were compared to
patients who underwent LDLT for
alcoholic liver disease without
alcoholic hepatitis ( n = 461 ) ,
patients with
alcoholic hepatitis were significantly younger ( 43.2 + - 8.5 vs. 48.2 + - 9.1 years , p = 0.001 ) and had higher Child 's ( 10.9 + - 1.5 vs. 9.8 + - 1.8 ) and MELD scores ( 22.1 + - 4.5 vs. 18.4 + - 5.9 , p = 0.000 ) . -
pubmed
CONCLUSION : Living donor liver transplantation can be successfully performed with good survival for
patients with severe
alcoholic hepatitis . -
pubmed
The relative benefits in
patients with and without established
atherosclerotic cardiovascular disease for different outcomes with these classes of drugs remain undefined . -
pubmed
For both drug classes , this treatment effect was restricted to a 14 % reduction in those with established
atherosclerotic cardiovascular disease ( HR , 0.86 ; 95 % CI , 0.80 - 0.93 ; P=0.002 ) , whereas no effect was seen in
patients without established
atherosclerotic cardiovascular disease ( HR , 1.01 ; 95 % CI , 0.87 - 1.19 ; P=0.81 ; P interaction , 0.028 ) . -
pubmed
Their distinct clinical benefit profiles should be considered in the decision - making process when treating
patients with
type 2 diabetes mellitus . -
pubmed
We aimed to examine the association between urinary
BPA and
TNs in
women who are more susceptible to
TNs . -
pubmed
Gleno - humeral abduction measurement in
patients with
Ehlers - Danlos syndrome . -
pubmed
METHODS AND MATERIAL : Retrospective case - control study comparing 110
patients with known
EDS ( cases ) to 100 controls . -
pubmed
A stratification model using regression analyses was developed to assign the
patients to risk categories for
wound healing and the time - to - heal . -
pubmed
An ecologically important tropical freshwater microalga ,
Scenedesmus quadricauda , was exposed to
Ni toxicity under two temperature regimes , 25 and 35 C to investigate the interactive effects of warming and different
Ni concentrations ( 0.1 , 1.0 and 10.0 ppm ) . -
pubmed
Evolution of platelet function in adult
patients with
chronic immune thrombocytopenia on
romiplostim treatment . -
pubmed
Eight
patients with
syndromic craniosynostosis underwent midface distraction osteogenesis using the type Z'gok between 2016 and 2017 ( Z'gok group ) . -
pubmed
Romiplostim in
patients with refractory
aplastic anaemia previously treated with immunosuppressive therapy : a dose - finding and long - term treatment phase 2 trial . -
pubmed
In this phase 2 trial we aimed to assess the activity and safety of
romiplostim in
patients with
aplastic anaemia who were previously treated with immunosuppressive therapy . -
pubmed
Eligible
patients were aged 19 years or older , and had
aplastic anaemia confirmed by bone marrow and cytogenetic studies and
thrombocytopenia ( platelet count & lt;=30 x 109 / L ) , an Eastern Cooperative Oncology Group performance status score of 2 or lower , and were previously treated with immunosuppressive therapy , including at least one course of
antithymocyte globulin plus
cyclosporin . -
pubmed
Treatment - related adverse events occurred in three ( 9 % ) of 35
patients , including grade 1 or 2
myalgia ,
fatigue , and
dizziness . -
pubmed
17 ( 49 % ) of 35
patients had adverse events of grade 3 or higher ; seven ( 20 % ) had serious adverse events ( one event of
febrile neutropenia ,
cataract ,
retinal detachment ,
macular fibrosis ,
inguinal hernia ,
appendicitis ,
cellulitis ,
tendon injury , and
transfusion reaction ) ; and one
patient died from
sepsis during treatment ; none of these events were related to treatment . -
pubmed
INTERPRETATION : Romiplostim seems to be active and has a favourable safety profile in
patients with refractory
aplastic anaemia . -
pubmed
We describe the case of a 42 - yr - old female
patient with a 2 - yr history of
headache that has progressively worsened . -
pubmed
The
patient presented a
paresis of the oculomotor nerve that completely resolved in the 3 - mo follow - up . -
pubmed
Recurrent
ovarian cancer remains confined in the peritoneal cavity in > 80 % of the
patients , providing an opportunity for locoregional administration of novel therapeutics , including gene and viral therapy approaches . -
pubmed
In this review we cover recent advances in
adenovirus - based oncolytic therapies targeting
ovarian cancer and recent advances in mapping immune responses to oncolytic virus therapies in
ovarian cancer . -
pubmed
RESULTS : Thirteen articles reporting on 30 cases of BI during
inguinal hernia repair from 1967 to 2017 were included ( 19
boys , 2
girls , 9 unknown ) . -
pubmed
Analysis of a loquat tree with
leaf curl symptoms by deep sequencing revealed a novel virus with a single - stranded RNA genome , for which the name "
loquat virus A " ( LoVA ) was proposed . -
pubmed
Delirium is prevalent in older hospital
inpatients and associated with adverse outcomes : results of a prospective multi - centre study on World
Delirium Awareness Day . -
pubmed
Fifty - nine
patients were divided into two groups :
caries free ( A group ) and
caries active ( B group ) . -
pubmed
Expression and short - term prognostic value of miR-126 and miR-182 in
patients with
acute stroke . -
pubmed
Expression and short - term prognostic value of miR-126 and miR-182 in
patients with
acute stroke were investigated . -
pubmed
In total , 153
patients with
acute stroke admitted to the Second Affiliated Hospital of Soochow University from February 2016 to February 2018 were enrolled into the observation group as group A [ 88
patients with
acute cerebral infarction (
AIS ) ] or group B [ 65
patients with
cerebral hemorrhage (
ICH ) ] . -
pubmed
The receiver operating characteristic ( ROC ) curve was employed to explore the value of miR-126 and miR-182 , alone or in combination , in predicting the prognosis of
acute stroke patients . -
pubmed
The expression levels of miR-126 and miR-182 are associated with the neurological function , self - care ability , and prognosis in
patients with
acute stroke is highly valuable for predicting the prognosis of
patients . -
pubmed
Drawing the parallelism between vitelline layer of
echinoderm eggs and the
zona pellucida of
mammalian eggs , we also discuss the importance of the egg surface in mediating monospermic fertilization . -
pubmed
The novel
severe acute respiratory syndrome - coronavirus-2 pandemic has spread to Africa , where nearly all countries have reported laboratory - confirmed cases of novel
coronavirus disease (
COVID-19 ) . -
pubmed
Taken together , the combined properties of the co - gels , including their stability and capacity to control both cell recruitment and cell phenotype within the
murine wound bed , strongly supports the potential of the co - gel scaffolds for improved treatment of chronic non - healing
wounds . -
pubmed
Focused Clinical Question : In
patients with endosseous dental implants that demonstrate
peri - implantitis , does surgical bone augmentation with adjunctive laser implant surface disinfection have an effect on implant survival rates , and do these rates differ based on laser treatment modality ? -
pubmed
Aggressive
angiomyxoma to 57 - year old
man . -
pubmed
Severe acute respiratory syndrome coronavirus 2 (
SARS - CoV-2 ) has placed unprecedented pressure on healthcare systems , even in advanced economies . -
pubmed
A 43 - year - old
woman presented with
impaired vision and redness in her left eye of 2 weeks duration . -
pubmed
Based on the recent
cat scratch and the ocular findings ,
cat scratch disease (
CSD ) was suspected . -
pubmed
Natural substances with antioxidant effects may benefit prevention and treatment of
people with or prone to
bone diseases after menopause , such as
osteoporosis . -
pubmed
RESULTS : A total of 588
patients with severe
sepsis /
septic shock were enrolled . -
pubmed
Based on the Sepsis-1 definition , there were 159 non - septic
shock patients and 429
septic shock patients . -
pubmed
Compared with the non -
septic shock patients ,
lactate ( Lac ) level , sequential organ failure assessment ( SOFA ) score , fluid balance on the first day , and ratio of mechanical ventilation , 12 - hour
acute kidney injury (
AKI ) , renal replacement therapy ( RRT ) , and postoperative ICU transition in the
septic shock patients were significantly increased and the proportion of emergency admission to ICU was significantly decreased . -
pubmed
Based on the Sepsis-3 definition , there were 383 non - septic
shock patients and 205
septic shock patients ; the results of clinical data analysis between the two groups were similar to those based on
Sepsis-1 . -
pubmed
Based on
Sepsis-1 , there was no significant difference in 90 - day mortality between non - septic
shock and
septic shock patients [ 23.90 % ( 38/159 ) vs. 29.37 % ( 126/429 ) , P > 0.05 ] . -
pubmed
However , based on
Sepsis-3 , the 90 - day mortality of
patients with
septic shock was significantly higher than that of patients with non - septic
shock [ 37.56 % ( 77/205 ) vs. 22.72 % ( 87/383 ) , P < 0.01 ] . -
pubmed
BACKGROUND : The impact of incidentally detected
hepatocellular carcinoma (
iHCC ) in explanted liver on the prognosis of the
patients undergoing orthotopic liver transplantation remains controversial with several studies reporting survival worse than true
non - hepatocellular carcinoma (
non - HCC ) recipients . -
pubmed
METHODS : The present study retrospectively analyzed the
patients ' demographics ,
tumor characteristics , and outcomes of
iHCC in adult
patients undergoing LDLT for non -
HCC indications at our center between August 2009 and March 2018 . -
pubmed
iHCC was detected in the explanted livers in 28
patients ( 5.1 % ) out of 545 LDLTs . -
pubmed
CONCLUSIONS : Incidence of
iHCC in explanted livers after LDLT is low and most
patients have very early - stage
tumors with excellent
recurrence - free survival . -
pubmed
We found a high percentage ( 61 per cent ) of falsely positive results in
patients with various
hematological diseases without evidence of
prostatic carcinoma by the colorimetric evaluation . -
pubmed
One hundred sixty - one
patients with advanced
Hodgkin ' s disease achieved complete remission after combination chemotherapy . -
pubmed
In a
patient with no recent
myocardial insult , uptake of
technetium-99 m diphosphonate was noted in a region corresponding to massive calcification of the mitral annulus . -
pubmed
Antidotes protect
corn from
thiocarbamate herbicide injury . -
pubmed
11
patients with
ischaemic heart disease (
IHD ) with
single vessel disease served as controls . -
pubmed
Myocardial perfusion defects in
patients with
X - syndrome were similar to those in patients with moderate , but haemodynamically significant , single vessel disease . -
pubmed
The
mice were killed at varying periods of time after
hemorrhage to obtain KC from the liver , and assessed for their capacity to present antigen to a
sensitized clone Th / cell line (
D10.G4.1 ) . -
pubmed
Analysis of a cellular model to account for the natural history of
infection by the
hepatitis B virus and its role in the development of primary
hepatocellular carcinoma . -
pubmed
Infection with the hepatitis B virus (
HBV ) can have many different outcomes . -
pubmed
We present two patients who experienced life - threatening immediate reactions and one
patient who developed generalized
urticaria following oral administration of
trimethoprim (
TMP ) and
sulfamethoxazole (
SMX ) combination . -
pubmed
These results suggest that the three
patients developed
type I hypersensitivity reactions to
TMP . -
pubmed
In our
patients skin prick tests with
TMP were useful in
TMP hypersensitivity diagnosis . -
pubmed
A linear function , 70 ( + /- 7.3 ) + -0.15 ( + /- 0.056 ) x dose ( + /- SD ) , adequately described the excess numbers of
rats with
lung cancers over a beta - radiation dose range to the lungs of 6.8 to 250 Gy for two groups of
rats with the highest doses to the lungs after a single exposure and for two groups with the highest doses after repeated exposure . -
pubmed
It is not new but has only relatively recently become a parameter to be measured in
patients treated for
cardiovascular disease . -
pubmed
Diuretic therapy had a greater negative impact on the quality of life of
hypertensive patients than
captopril ,
propranolol , or
methyldopa alone . -
pubmed
In a case - control study of 177
HIV - seropositive and 326 seronegative women and their newborns in Nairobi , Kenya , maternal
HIV infection at term was independently associated with travel to other African countries [ odds ratio ( OR ) 4.9 , P less than 0.0001 ] , history of a blood transfusion since 1980 ( OR 3.5 , P = 0.01 ) , history of more than one sexual partner in the previous 5 years ( OR 1.8 , P = 0.02 ) and unmarried status ( OR 1.8 , P = 0.02 ) . -
pubmed
Neonates of
HIV - positive and
HIV - negative women differed little with respect to occurrence of
congenital malformations ,
stillbirths , in - hospital mortality , sex , APGAR score , or gestational age . -
pubmed
However , the mean
birth weight of singleton neonates of
HIV - positive women was significantly lower than that of controls ( 3090 versus 3220 g , P = 0.005 ) , and
birth weight was less than 2500 g in 9 % of cases and 3 % of controls ( OR 3.0 , P = 0.007 ) . -
pubmed
Mitosis in embryonic
trisomy 1
mouse eye . -
pubmed
Cytotoxic effects of six angiographic
contrast media on
human endothelium in culture . -
pubmed
Responses to ultraviolet - inactivated antigen prepared from
BKV - infected fibroblasts were compared to those elicited against a mock antigen preparation and an unrelated control antigen (
tetanus toxoid , TET ) . -
pubmed
We prepared
99mTechnetium ( V ) DMSA ( pentavalent form ) as an imaging agent for eighteen
patients with proven
nasopharyngeal carcinoma . -
pubmed
The
nasopharyngeal tumour showed tracer accumulation in only 5 out of the 18
patients ( 28 % ) . -
pubmed
Two
patients who received 150 mg of
ACNU and daily 600 mg of
UFT in combination with radiation therapy showed severe
myelosuppression in the early stage of treatment , and the combination therapy was aborted . -
pubmed
Two of four
patients who received 100 mg of
ACNU and daily 400 mg of
UFT did not show such severe side effects and two showed transient , moderate
myelosuppression and
vomiting . -
pubmed
Regulation of intakes of water and
NaCl solutions in
Fischer 344 rats : contrasts and comparisons between
strains . -
pubmed
We present an overview of the differences in intakes of both water and
NaCl between different
strains of
rat , with emphasis on Fischer 344 ( F344 ) and Sprague - Dawley ( SD ) strains . -
pubmed
Relative to SD ,
rats of the F344
strain show less spontaneous or secondary drinking both with food present and during food deprivation . -
pubmed
The water intake of
rats of the
F344 strain is strongly inhibited when water is added to their food , but
rats of the SD
strain show less inhibition and consume excessive amounts of fluid . -
pubmed
In studies of primary drinking , induced by treatment with various dipsogens ,
rats of the F344
strain consumed water in amounts that were generally comparable to those expected from
rats of the SD
strain , with the exception of reduced intakes in response to either
polyethylene glycol - induced
hypovolemia or treatment with
isoproterenol . -
pubmed
We also review findings that
rats of the F344
strain show no spontaneous preference for dilute
NaCl solutions , and show that both a strong preference and a low preference threshold are induced by chronic treatment with
ramipril . -
pubmed
In the conservative group , six
patients underwent arthroscopy for
meniscal tears , four medial and two lateral . -
pubmed
Only seven
patients returned to sports , all experiencing recurrent episodes of giving way ,
effusions , and
pain . -
pubmed
The two remaining
patients both suffered
reinjury 3 years after their surgery . -
pubmed
We recommend arthroscopy and examination under anesthesia for the young
patient with
ACL tears . -
pubmed
In vitro immunization procedures , using sera of
athymic mice bearing
human WOC ovarian
tumors or CM III mammary
tumors as immunizing antigen , induced a highly efficient formation of mABs ( 44 % of
antibody - producing clones ) reacting with
human ovarian and/or
mammary tumor cells . -
pubmed
Immunogenicity of normal
mouse components in the sera from
tumor bearers can be excluded since control immunization with sera of normal
athymic mice yielded no mABs reacting with
mouse or human cell lines . -
pubmed
Focal
atrial tachycardia with frequencies up to 200 / min in an 11 - year - old
girl had been resistant to drugs over a period of 5 years . -
pubmed
Clinical and/or biochemical evidence of
hypothyroidism occurred in three
patients , two of whom required treatment with
L - thyroxine . -
pubmed
An additional
patient had persistent
hyperthyroxinemia but no clinical evidence of
hyperthyroidism . -
pubmed
In the past 11 years we have operated on three
patients with " tiny " parathyroid
adenomas ( less than 60 mg ) . -
pubmed
Permanent microscopic sections confirmed the diagnosis of parathyroid
adenoma in all three
patients . -
pubmed
The culture of
human foetal pancreatic tissue may be useful in maintaining responsive beta cells and may help to ensure an adequate amount of donor tissue for future transplantation into
diabetic patients . -
pubmed
Effect of
venous hypertension on
canine hind limb lymph . -
pubmed
The effect of acute and chronic
venous hypertension on the lymph draining from the hind limb has been studied in 10
dogs . -
pubmed
The saline - insoluble particulate material obtained by pulmonary lavage from four
patients with
alveolar proteinosis was analyzed for total lipid ( 52 % ) , protein ( 44 % ) , and
carbohydrate ( 4 % ) . -
pubmed
Acute
inflammation and granulation tissue formation in
neutropenic rats . -
pubmed
[ Effectiveness of the agents of the 2d series in treating
patients with
chronic destructive tuberculosis of the lungs ] . -
pubmed
Congenital lipoprotein lipase deficiency and
hyperlipemia in the young
puppy . -
pubmed
Effect of
isopropamide on response to oral
cimetidine in
patients with
Zollinger -- Ellison syndrome . -
pubmed
Patients with
Zollinger - Ellison syndrome whose gastric acid secretion or symptoms were not controlled by
cimetidine in conventional dosage were selected for studies of responsiveness of their acid secretion to increasing doses of
cimetidine , used either alone or in combination with a long - acting anticholinergic agent ,
isopropamide iodide . -
pubmed
Basal and stimulated by means of
isoproterenol lipolysis was similar in adipose tissue either in persons with normal arterial blood pressure or in
patients with
hypertensive disease . -
pubmed
Arthritis in a 15 - year - old
boy with
juvenile diabetes mellitus . -
pubmed
The clinical and pathological features of 20
patients with coexistent
squamous cell carcinoma and
adenocarcinoma of the uterine cervix have been analyzed . -
pubmed
In an attempt to resolve this apparent disagreement , we exposed
White Carneau pigeons to drinking water containing
calcium ( 100 ppm ) ,
magnesium ( 30 ppm ) , lead ( 0.8 ppm ) , or
cadmium ( 0.6 ppm ) and used a 2(4)-factorial design to measure the effects of these elements in
atherosclerosis and
hypertension . -
pubmed
We suggest that , if these results with the
pigeon can be applied to
humans , the incidence of
aortic atherosclerosis and
hypertension should be significantly higher in areas where the drinking water contains
magnesium , lead , and
cadmium with a relatively low
calcium concentration . -
pubmed
In 34
patients with different chronic
skin diseases ( including
eczemas ,
lichen ruber ,
erythrodermia ,
pyodermia ,
pemphigus erythematosus ,
vasculitis ,
parapsoriasis varioliformis ,
scleroderma adultorum Buschke ,
prophyria cutanea tarda ,
rosacea ,
dermatomyositis ,
erythematodes chronicus discoides and
indurative tuberculosis ) , X - ray studies revealed sacroiliac - changes consistent with a low - grade
inflammation . -
pubmed
We reviewed 32
children with
lower extremity injuries caused by power lawn mowers . -
pubmed
METHOD : Echoic memory was investigated in 20
schizophrenic subjects and 20 age- and IQ - matched normal comparison subjects with the use of nondelayed and delayed tone matching . -
pubmed
RESULTS :
Schizophrenic subjects were markedly impaired in their ability to match two tones after an extremely brief delay between them ( 300 msec ) but were unimpaired when there was no delay between tones . -
pubmed
With respect to the
neoplasms ,
Kaposi ' s sarcoma was observed in
patients with different degrees of immunosuppression . -
pubmed
AIMS : To evaluate further the relation between
gastric malignant lymphoma of the mucosa associated lymphoid tissue ( MALT ) and
Helicobacter pylori . -
pubmed
Unilateral complete
airway obstruction persisted in 8 of the 12
rabbits . -
pubmed
[ Effects of zuzhongping on ischemic volume in the
rat model of
middle cerebral artery occlusion ] . -
pubmed
Effect of
epinephrine treatment during late
ischemia and early reperfusion on regional myocardial function and
infarct size in partially infarcted reperfused
porcine hearts . -
pubmed
Case report -- The first
patient male , aged 23 , presented a
sequestrum in the vestibular alveolar wall in correspondence with 1.1 and 1.2 . -
pubmed
The
patient underwent two operations ( one using a craniotomy route and the other using a trans - sphenoidal route ) to remove a giant
pituitary adenoma . -
pubmed
Impact of axillary lymph node dissection on the therapy of
breast cancer patients . -
pubmed
PURPOSE : We studied a series of 283
breast cancer patients retrospectively to determine the actual benefits of axillary lymph node dissection ( ALND ) for these
patients . -
pubmed
CONCLUSION : The benefits of ALND vary greatly for different groups of
breast cancer patients , and controlled studies may be needed to determine whether ALND is necessary for all
breast cancer patients . -
pubmed
Conformational features of a synthetic cyclic peptide corresponding to the complete V3 loop of the RF
HIV-1 strain in water and water /
trifluoroethanol solutions . -
pubmed
The
disulfide - bridge - closed cyclic peptide corresponding to the whole V3 loop of the RF
HIV-1 strain was examined by proton two - dimensional NMR spectroscopy in water and water /
trifluoroethanol solutions . -
pubmed
[
Acute intrahepatic bleeding in a male
patient with
focal nodular hyperplasia ] . -
pubmed
HISTORY AND CLINICAL FINDINGS : A 45 - year - old
man had acute bouts of
pain in the right lower thorax with radiation to the mid - thorax and upper abdomen . -
pubmed
Substrates were crosslinked with 0 % or 0.25 %
glutaraldehyde , populated with cells , and grafted to full - thickness
wounds on athymic
mice ( n = 6 / condition ) . -
pubmed
METHODS : Between 1982 and 1992 , 6
patients with
Crohn ' s disease and
leukemia underwent allogeneic marrow transplantation and were followed up clinically . -
pubmed
RESULTS : Five
patients had active
Crohn ' s disease before transplantation , and 3 had clinical evidence of
sclerosing cholangitis . -
pubmed
One patient died of
septicemia 97 days after transplantation ; 5
patients were observed for 4.5 , 5.8 , 8.4 , 9.9 , and 15.3 years after transplantation . -
pubmed
Four of 5
patients evaluated had no signs or symptoms of
Crohn ' s disease after transplantation . -
pubmed
One
patient with mixed donor - host hematopoietic chimerism had a
relapse of
Crohn ' s disease 1.5 years after transplantation . -
pubmed
CONCLUSIONS : Four of 5
patients followed up for 4.5 to 15.3 years after allogeneic hematopoietic cell transplantation remained free of
Crohn ' s disease . -
pubmed
SUBJECTS : One hundred and seventy
children , aged 8 - 36 months , were recruited at the clinical ward and public health service section of the hospital : 61 normal
children , 49 moderately malnourished (
underweight )
children and 60 severely malnourished
children ( 19
kwashiorkor , 30
marasmus , and 11 marasmic
kwashiorkor children ) . -
pubmed
MEASUREMENTS AND MAIN RESULTS : Seventy - five
patients had neither signs of
respiratory distress nor deterioration in gas exchange during the trial and were extubated . -
pubmed
CONCLUSIONS : Three - quarters of ventilated
children can be successfully weaned after a trial of spontaneous breathing lasting 2 h. Both tidal volume and frequency - to - tidal volume ratio indexed to
body weight were poor predictors of weaning failure in the study population . -
pubmed
A 69 - year - old
man with chronic
dizziness . -
pubmed
We report the unrecognized accidental intratracheal insertion of a nasogastric tube , following endotracheal intubation in a
patient scheduled to undergo right lower lobectomy for
carcinoma . -
pubmed
The 1p31 region shows loss of heterozygosity in up to 50 % of
human breast cancers , indicating the presence of a
tumor suppressor gene in this location . -
pubmed
The aim of this study was to investigate the efficacy of MC in isolated , perfused
rat hearts , and to see whether MC itself induced
myocardial cell injury and functional impairment . -
pubmed
Langendorff - perfused
rat hearts ( n = 89 ) from several experimental series subjected to 30 min of global
ischaemia and 60 min of reperfusion were retrospectively analysed . -
pubmed
SUBJECTS : 2158
patients aged & gt;40 years were screened by questionnaires and case record reviews ; 357 patients with past or present signs or symptoms of
heart disease were identified , of whom 126 were eligible for and consented to examination . -
pubmed
RESULTS : 15
patients ( 12 % ) had
left ventricular systolic dysfunction . -
pubmed
Significant improvement in symptoms has been reported with the use of continuous positive airway pressure in
patients with
OSA . -
pubmed
The aim of the present study was to describe the results of the evaluation of brain - dead
patients as potential cardiac donors in a French teaching hospital that manages the largest number of
brain - dead patients in France . -
pubmed
RESULTS : Seventy - one consecutive
brain - dead patients admitted to the intensive care unit of the Academic Hospital of Nancy from October 1st , 1998 to September 30 , 1999 were analyzed . -
pubmed
Color Doppler imaging study in
patients with
primary open - angle glaucoma treated with
timolol 0.5 % and
carteolol 2 % . -
pubmed
PURPOSE : To evaluate with color Doppler imaging ( CDI ) , in
patients with
primary open - angle glaucoma (
PDAG ) , the possible influence on ocular hemodynamics of a beta - blocking agent with intrinsic sympathomimetic acitivity (
carteolol 2 % ) compared to a beta - blocker agent without this activity . -
pubmed
A
man with
hereditary exostoses and high - grade
non - Hodgkin ' s lymphoma of the bone . -
pubmed
We present a case report of a 52 - year - old
man with
MCE who had a palpable mass at the left shoulder . -
pubmed
Hepatoprotective action of abhrak bhasma , an ayurvedic drug in
albino rats against
hepatitis induced by
CCl4 . -
pubmed
Abhrak bhasma is a commonly used ayurvedic drug against many diseases including
hepatitis . -
pubmed
It is tested in
albino rats using a model of
hepatitis induced by a single dose of
CCl4 ( 3 ml / kg body wt ) . -
pubmed
[ Gastrointestinal surgery in
patients with
ovarian cancer ] . -
pubmed
OBJECTIVES : The objectives were to assess indications as well as outcome and morbidity of gastrointestinal surgery in
patients with
ovarian cancer . -
pubmed
METHODS : The study included 74
patients with primary
ovarian cancer who had debulking surgery ( bowel surgery ) from 1987 to 2001 . -
pubmed
Tophaceous gout in an amputation stump in a
patient with
chronic myelogenous leukemia . -
pubmed
This case report describes the development of a
gouty tophus at a site of remote traumatic forearm amputation in a
patient with
chronic myelogenous leukemia (
CML ) . -
pubmed
Anatomic basis and technical aspects of a new
brachial plexus avulsion injury model in the
rat . -
pubmed
In contrast to conventional virus isolation , all muscle samples from infected pigs were positive for viral nucleic acid by PCR , except for muscle from one animal infected with the American
strain of
PRRSV . -
pubmed
One of the five groups was fed muscle obtained from US donor
pigs that was also spiked with the American
strain of
PRRSV . -
pubmed
Reduction of mitochondrial electron transport complex activity is restricted to the ischemic focus after transient focal
cerebral ischemia in
rats : a histochemical volumetric analysis . -
pubmed
Micrometastases in axillary lymph nodes and bone marrow of lymph node - negative
breast cancer patients -- prognostic relevance after 10 years . -
pubmed
The long - term prognostic significance of immunohistochemically detectable occult
tumor cells in bone marrow and axillary lymph nodes of
breast cancer patients considered to be lymph node - negative in multilevel haematoxylineosin ( H&E ) lymph node sectioning was analyzed . -
pubmed
Combining phacoemulsification and vitrectomy in
patients with proliferative
diabetic retinopathy . -
pubmed
Multiple reports confirm the safety of combined surgery in
patients with proliferative
diabetic retinopathy . -
pubmed
SUMMARY : In select
patients with
diabetes , combining vitrectomy with phacoemulsification and posterior capsulectomy allows
patients who often have bilateral
vitreoretinal disease to come to a stable postoperative vision in the eye requiring vitreous surgery much earlier than three separate procedures spread out over months or years . -
pubmed
The
canine animal was chosen since it can present with spontaneous
bladder carcinomas mimicking
human pathology . -
pubmed
Primary cultures of two normal
canine bladder urothelium and two
canine primary
bladder tumours were first studied . -
pubmed
We then investigated in vivo , in two normal and two spontaneous
tumour bearing
dogs , the transduction of urothelial cells following direct intravesical instillation of 2.10(4 ) to 3.10(6 ) of the retroviral vector . -
pubmed
RESULTS : Transduced cells were evidenced in all primary cultures of
canine normal urothelium and
transitional cell carcinoma . -
pubmed
Bladder cryosections from
tumour - bearing
dogs displayed transduction of superficial layers of
urothelial cancer cells without passing through lamina propria . -
pubmed
CONCLUSION : These results demonstrate for the first time the feasibility of in vivo
retroviral transduction of
bladder cancer using a clinically relevant procedure . -
pubmed
Cortical inhibition in first - degree relatives of
schizophrenic patients assessed with transcranial magnetic stimulation . -
pubmed
First - degree relatives of
schizophrenia patients , who share various degrees of genetic vulnerability with the
patients , but are free from confounds related to medication and/or florid
psychosis , have not been studied to date . -
pubmed
METHODS : We measured deep inspiration ( DI)-induced bronchodilation in 15
individuals with and without
COPD ( 67 + /- 2.2 yrs of age , mean + /- SEM ) undergoing lobar resection for peripheral pulmonary nodule . -
pubmed
The authors compared 40
subjects with
essential hypotension ( mean
systolic BP = 97.6 mmHg ) with 40 normotensive controls ( mean
systolic BP = 124.1 mmHg ) using 6 computer - based tasks measuring tonic and phasic alertness ; selective , divided , and sustained attention ; and working memory . -
pubmed
The purpose of this study is to investigate the relationship between cell
death , loss of mitochondrial membrane potential ( MMP ) and reduction of metabolic rates for in vitro cultured
mouse hepatocytes after acute exposure to two doses of
chloroform . -
pubmed
Recent outbreaks of
Trypanosoma brucei rhodesiense sleeping sickness in Soroti District of eastern Uganda have demonstrated the important role
cattle can play as reservoirs of this parasite . -
pubmed
brucei in
cattle is characterized by an acute phase with high levels of
parasitaemia and a decline in
PCV . -
pubmed
The acute phase is followed by a chronic phase during which the
PCV remains low but stable and the
parasitaemia is low . -
pubmed
Despite significant differences in
parasitaemia , the proportion of tsetse flies that developed
metacyclic infections after a first bloodmeal on the infected
cattle did not differ significantly between the acute and chronic phases or the phase of mixed
T. - pubmed
Its action on platelet
TxA2 has highlighted its role as an anti -
thrombotic agent in cardiovascular
patients . -
pubmed
Primary
HSV infection was certain or likely in all cases , including an
HSV2 superinfection of an anti - HSV1 - positive patient and two
HSV superinfections of hepatitis B virus (
HBV)-related
chronic liver disease . -
pubmed
In these latter patients ,
HSV diagnosis was totally unsuspected , despite
fever . -
pubmed
We describe 2
patients who experienced
recurrence after treatment for the primary
tumor . -
pubmed
Human S - cone vision : relationship between perceptive field and
ganglion cell dendritic field . -
pubmed
Aggressive
angiomyxoma of the vulva or perineum : report of three
patients . -
pubmed
BACKGROUND : Aggressive
angiomyxoma is a rare , locally aggressive
soft tissue tumour that chiefly involves the vulvoperineal region of young female
patients . -
pubmed
CASES : We present three
patients who each had an aggressive
angiomyxoma treated initially for another presumed diagnosis . -
pubmed
Two
patients required immediate repeat surgical procedures for incomplete
tumour excision . -
pubmed
The third
patient developed a
recurrence two years after the initial surgery . -
pubmed
In one
patient , hormonal therapy was used postoperatively because the evaluation of the
tumour margins was uncertain . -
pubmed
Harpoon markers were used to aid in
tumour localization in another
patient prior to resection . -
pubmed
CONCLUSION : Clinicians should consider the diagnosis of aggressive
angiomyxoma when a
patient presents with an atypical vulvoperineal mass , as an incorrect diagnosis may lead to repeated surgical procedures . -
pubmed
Among the
structural abnormalities affecting the
human Y chromosome , dicentric chromosomes are the most common . -
pubmed
PURPOSE : To identify vitreous proteins that were differentially expressed in
patients suffering from proliferative
diabetic retinopathy with active neovascularization . -
pubmed
METHODS : The vitreous samples of 15 active proliferative
diabetic retinopathy patients were analyzed by two - dimensional gel electrophoresis and mass spectrometry , and the results were compared with those from age - matched
patients with
macular hole . -
pubmed
Five proteins were upregulated in the proliferative
diabetic retinopathy patients , and three were downregulated ( p value & lt ; 0.05 ) . -
pubmed
CONCLUSIONS : We constructed vitreous protein profiles for proliferative
diabetic retinopathy patients and identified eight candidate proteins believed to be involved in the pathogenesis of proliferative
diabetic retinopathy . -
pubmed
METHODS : Retrospective medical record review ( 1982 to 2003 ) for
patients with a diagnosis of
Duane syndrome ( examined by a pediatric ophthalmologist ) who were bilaterally affected and had no prior ocular surgery . -
pubmed
Eight
patients treated with an extracranial - intracranial vascular bypass graft over a period of 44 months for symptomatic
cavernous sinus aneurysms are reviewed . -
pubmed
At a mean follow - up of 20 months , seven
patients ( 87.5 % ) had an excellent outcome ( Glasgow Outcome Score 5 ) while one
patient suffered a
perioperative stroke . -
pubmed
The results of this series seem to indicate that cerebral revascularisation is an effective treatment for
patients with symptomatic
cavernous sinus aneurysms . -
pubmed
METHODS : Fifty - three
patients ( M / F = 43/10 , 62 + /- 14 years ) with typical
AFL were included . -
pubmed
BACKGROUND : Leptospira are the parasitic bacterial organisms associated with a broad range of mammalian hosts and are responsible for severe cases of
human Leptospirosis . -
pubmed
Two
patients , who had been diagnosed and treated surgically for hyoid bone insertion
tendinitis , were presented in this study . -
pubmed
DCs that are manipulated to present
tumor antigens induce antitumor immunity in animal models and preclinical
human studies . -
pubmed
A discussion of 2 double - blind studies comparing
risperidone and
quetiapine in
patients with
schizophrenia . -
pubmed
[ Implication of middle - mass molecule peptides of blood plasma in assessment of
intoxication syndrome in
patients with
bacterial tonsillitis ] . -
pubmed
High therapeutic efficacy of an immunomodulating drug tamerit in combined therapy of
patients with
bacterial tonsillitis is shown . -
pubmed
The change in
atrophy in relation to neutrophil infiltration was significant in Hp ( + )
patients ( P = 0.0001 ) . -
pubmed
The change in
atrophy in relation to neutrophil infiltration in
patients with GG genotype was significant ( P = 0.002 ) . -
pubmed
People were asked if they had a
sore throat and/or
skin sores and asked about current or recent use of antibiotics ; all throats and any
pyoderma lesions were swabbed for
bacterial culture . -
pubmed
Myelination as assessed by conventional MR imaging is normal in young
children with
idiopathic developmental delay . -
pubmed
MATERIALS AND METHODS : A total of 93
children ( 31 controls , 62 with
idiopathic developmental delay [
IDD ] ) aged 17 to 46 months were identified on the basis of having brain MR imaging for evaluation of
IDD ( cases ) or for another condition ( controls ) . -
pubmed
Children with diseases that primarily affect white matter or overt
intracranial lesions or malformations were excluded . -
pubmed
Developmental quotients ( DQs ) were calculated for all
children with
IDD on the basis of clinical history , examination , and psychometric testing . -
pubmed
Neuroimaging evaluation of maturity of subcortical myelination is not a marker of
IDD in young
children , and the isolated " finding " of delayed myelination should be interpreted with caution . -
pubmed
Neisseria gonorrhoeae expresses numerous surface proteins that mediate bacterial adherence and invasion during
infection . -
pubmed
In contrast ,
fruit damage in
methoxyfenozide- and
lambda - cyhalothrin - treated fruit was observed earlier for resistant
codling moth . -
pubmed
The
patient presented with an
epigastric pain for two months . -
pubmed
Control subjects included 65 non - SA
patients admitted to the same hospital with
ACS matched by age , sex and year of hospitalization . -
pubmed
MMTV - induced pregnancy - dependent
mammary tumors : early history and new perspectives . -
pubmed
Almost 60 years ago , Foulds carefully described for the first time a particular type of
mouse mammary tumor that appeared in the glands of pregnant females and disappeared shortly after delivery . -
pubmed
Since then , the attention that researchers paid to the
Mouse Mammary Tumor Virus (
MMTV)-induced pregnancy - dependent
tumors has not vanished through the years . -
pubmed
This was because the information obtained from
mice carrying
MMTV variants that were able to induce pregnancy - dependent
tumors was meaningful for studying different aspects of
mammary tumor biology . -
pubmed
In the analysis of the association between
tumor morphology and behavior , the mechanisms underlying progression towards autonomy , the impact of different genes during
cancer initiation and development , and the relevance of host genetic background for
tumor incidence and hormone - dependence ,
mouse strains carrying these
MMTV variants have been very important tools that could not have been replaced with any other available model . -
pubmed
The goal of this article is to provide a succinct chronicle of the experiments and observations made in the
MMTV - induced pregnancy - dependent models that most significantly contributed to the
mouse mammary tumor biology field . -
pubmed
In addition , the possibility to use these
MMTV variants as alternative models for analyzing
mammary tumor stem cells and pregnancy - associated
breast cancer in women is discussed . -
pubmed
METHODS : A prospective database of 878 conservatively treated
patients with ductal
carcinoma in situ was analyzed . -
pubmed
Among 327 excision plus radiotherapy
patients , there were 59
recurrences . -
pubmed
In an attempt to predict which
patients develop invasive
recurrences , prolonged time to recurrence was the only statistically significant factor . -
pubmed
CONCLUSIONS : The median time to local
recurrence for irradiated
patients was more than twice as long when compared with nonirradiated
patients , during which there is more time for local
recurrence to progress to invasion . -
pubmed
Irradiated
patients had more
breast scarring , making diagnosis by palpation and mammography harder . -
pubmed
Irradiated
patients develop invasive
recurrences at a statistically higher rate than nonirradiated
patients . -
pubmed
We designed a cross - sectional study with 225 asymptomatic
diabetic patients having no known
CAD . -
pubmed
A total of 109
patients ( 48.4 % ) was found to have silent
myocardial ischemia . -
pubmed
HIV /
AIDS taking shocking toll on black community . -
pubmed
LMWPEI combines low
cytotoxicity with high transfection efficiency in the
mouse lung in vivo , rendering it a promising strategy for pulmonary gene delivery . -
pubmed
OBJECTIVES : The goal of this study was to dosimetrically compare 3 - dimensional radiotherapy ( 3DCRT ) , intensity - modulated radiotherapy ( IMRT ) , and helical tomotherapy ( TOMO ) plans for whole abdominopelvic radiotherapy ( WART ) in
patients with
gynecologic cancer . -
pubmed
Clinical experiences will be needed for evaluation of feasibility of WART using TOMO in
patients with
gynecologic cancer . -
pubmed
Imaging diagnosis --
enostosis - like lesion in the femur of a
horse . -
pubmed
An
enostosis - like lesion was diagnosed in the left femur of a Swedish Warmblood
horse that had a left hindlimb
lameness of 3 weeks duration . -
pubmed
Enostosis - like lesions should be considered as a source of
pain in
horses with difficult to localize , moderate to severe chronic
lameness . -
pubmed
RESULTS : There were 839
patients ( 138
desmoids ) without genotype and 154 ( 30
desmoids ) with genotype . -
pubmed
The addition of cervical thrust manipulations to a manual physical therapy approach in
patients treated for mechanical
neck pain : a secondary analysis . -
pubmed
OBJECTIVES : To perform a secondary analysis on the treatment arm of a larger RCT to determine differences in treatment outcomes , adverse reactions , and effect sizes between
patients who received cervical thrust manipulation and those who received only nonthrust manipulation as part of an impairment - based , multimodal treatment program of manual physical therapy ( MPT ) and exercise for
patients with mechanical
neck pain . -
pubmed
BACKGROUND : A treatment regimen of MPT and exercise has been effective in
patients with mechanical
neck pain . -
pubmed
METHODS : Treatment outcomes from 47
patients in the treatment arm of a larger RCT , with a primary complaint of mechanical
neck pain , were analyzed . -
pubmed
A 32 - year - old
man presented with
thyroid eye disease and was found to have an orbital floor
fracture on routine preoperative imaging without any antecedent relevant symptom or sign . -
pubmed
To the best of the authors ' knowledge , this is the first report of an asymptomatic
orbital fracture in a
patient with
thyroid eye disease . -
pubmed
BACKGROUND : Both concomitant chemotherapy and altered fractionation radiotherapy ( RT ) have been shown to improve outcomes for
patients with locoregionally advanced
head and neck squamous cell carcinomas . -
pubmed
Seven ( 6 % )
patients changed from
cisplatin to
carboplatin because of
bone marrow toxicity . -
pubmed
Monoammonium glycyrrhizinate inhibited the
inflammation of LPS - induced
acute lung injury in
mice . -
pubmed
In this study , the anti - inflammatory effects of
MAG on lipopolysaccharide ( LPS)-induced
acute lung injury (
ALI ) in
mice and the possible mechanisms involved in this protection were investigated . -
pubmed
INTRODUCTION : previous studies have linked hippocampal volume change and
cognitive decline in older
adults with
dementia . -
pubmed
The authors examined hippocampal volume change and cognitive change in older nondemented
adults with and without
major depression . -
pubmed
METHODS : the sample consisted of 90
depressed individuals and 72 healthy , nondepressed
individuals aged 60 years and older who completed at least 2 years of follow - up data . -
pubmed
Depressed
patients with hippocampal volume loss are at greater risk of
cognitive decline . -
pubmed
Hepatocellular carcinoma (
HCC ) is one of the most common
solid cancers , representing the third cause of
cancer - related
death among cirrhotic
patients . -
pubmed
This protein was expressed in half of
human cancer cell lines but barely in normal
human fibroblasts tested . -
pubmed
The needles of
Pinus densiflora Siebold et Zuccarini , a representative Pinus species that grows in Korea , have been used in oriental traditional medicine as remedies for
rheumatitis ,
hemorrhage ,
cancer , etc . -
pubmed
Detection of
PRRSV circulation in herds without clinical signs of
PRRS : comparison of five age groups to assess the preferred age group and sample size . -
pubmed
A cross - sectional study was conducted to find the most effective diagnostic approach to detect circulation of
porcine reproductive and respiratory syndrome virus (
PRRSV ) . -
pubmed
This result indicates that 9- to 16 - week - old pigs are the preferred age group to detect
PRRS - virus , in herds without clinical signs of
PRRS . -
pubmed
Testing 12 blood samples in both rt - PCR and ELISA , with 6 samples in
pigs 9 weeks of age and 6 samples in pigs 16 weeks of age , will lead to a cost - efficient first evaluation of the
PRRSV infection - status in herds without clinical signs of
PRRS . -
pubmed
BACKGROUND : Despite the high prevalence of
depression in
people with
neurological disorders , no previous study has sought to summarise existing evidence on the use of antidepressants in this population . -
pubmed
METHODS : Embase , Pubmed , Psycinfo and Cochrane trial registers were searched for randomised controlled trials ( RCTs ) comparing the efficacy of antidepressant and placebo in the treatment of
depression in
adults with a
neurological disorder . -
pubmed
FINDINGS : 20 RCTs were included in the review , including
patients with
Parkinson ' s disease ,
multiple sclerosis ,
brain injury ,
epilepsy and
stroke . -
pubmed
INTERPRETATION : Antidepressants are effective for the treatment of
depression in
patients with
neurological disorders but the evidence for the efficacy of antidepressants in improving quality of life , and functional and cognitive outcomes is inconclusive . -
pubmed
The preparation was found to contain a low molecular - weight growth - inhibitory activity , suppressing both DNA synthesis in cultured
EAC cells and
EAC cell division in
tumor - bearing
mice . -
pubmed
Respiratory syncytial virus (
RSV ) is a major cause of
bronchiolitis and
pneumonia in infants , the immunocompromised , and the elderly in both developed and developing countries . -
pubmed
Epidemiological trends and clinical comparisons of
Mycobacterium tuberculosis lineages in Thai
TB meningitis . -
pubmed
Mycobacterium tuberculosis (
MTB )
strains were isolated from cerebrospinal fluids collected from individual
tuberculous meningitis (
TBM ) patients from 1996 to 2007 ( n = 184 ) and characterised based on IS6110 - restriction fragment length polymorphism ( RFLP ) , spoligotyping , Mycobacterium interspersed repetitive unit - variable number of tandem repeat ( MIRU - VNTR ) and large sequence polymorphisms ( LSPs ) . -
pubmed
Valproic acid and
sodium valproate for
neuropathic pain and
fibromyalgia in
adults . -
pubmed
MAIN RESULTS : We included three studies , two in
diabetic neuropathy ( 42
participants treated with
valproate , 42 with placebo ) , and one in
post - herpetic neuralgia ( 23 treated with
divalproex sodium , 22 with placebo ) . -
pubmed
Already , a library of magnetic nanoparticles has been developed , in which a wide range of targets , including DNA / mRNA , proteins , small molecules / drugs ,
bacteria , and
tumor cells , have been quantified . -
pubmed
Even though outcomes are excellent , with reported 5 - year
patient and graft survival exceeding 90 % and 80 % , 80 % and 75 % , 72 % and 65 % for
PBC ,
PSC , and
AIH , respectively , the issue of recurrent
autoimmune liver disease after orthotopic liver transplantation is increasingly recognized as a cause of graft dysfunction ,
death , and need for retransplantation . -
pubmed
Orally administered
AEE788 prolonged survival of
mice bearing
ependymoma - SC - driven orthotopic xenografts from 56 to 63 days , close to statistical significance ( log - rank p=0.06 ) . -
pubmed
Accelerated
mammary tumor onset in a
HER2 / Neu mouse model exposed to
DDT metabolites locally delivered to the mammary gland . -
pubmed
BACKGROUND : The association of
DDT (
dichlorodiphenyltrichloroethane ) with
breast cancer is controversial , but
animal studies directly linking
DDT to risk are lacking . -
pubmed
OBJECTIVES : We aimed to determine whether developmental exposure to
p , p - DDE stored in adipose tissue surrounding the
cancer - prone mammary epithelium of
MMTV - Neu mice influences
tumor development . -
pubmed
CONCLUSIONS :
p , p - DDE exposure at concentrations relevant to
human exposure accelerates
mammary carcinogenesis in
mice , possibly through hormonal and/or other actions . -
pubmed
Reversible
blindness : severe
pneumococcal induced
uveitis following
septicaemia . -
pubmed
This study illustrates the case of a middle - aged woman who presented with
sepsis and
purpura fulminans , found to be due to
Streptococcus pneumoniae infection . -
pubmed
She later developed
blindness from a dramatic ocular inflammatory response provoked by
pneumococcal antigens . -
pubmed
METHODS : The levels of the different markers were measured by enzyme - linked immunosorbent assay in pleural fluids from
patients with
MPM ( n = 61 ) ,
adenocarcinomas (
ADCA , n = 25 ) , or with benign
pleural effusions ( BPE , n = 15 ) . -
pubmed
There was a trend toward increasing inadvertent
PAN injury rate in
patients with high
body mass index and large
tumours . -
pubmed
Most of the 12
patients with potentially active erectile function before the operation recovered this function , and only one
patient ( 7 % ) with PAN
injury was still judged as inactive 12 months after surgery . -
pubmed
CONCLUSION : The proportion of
patients with
sexual dysfunction after LTME is low . -
pubmed
[ Experience of invasive surgical treatment of
renovascular hypertension in
children ] . -
pubmed
OBJECTIVES : To document any consistent clinical findings in a large cohort of
patients with
whiplash associated disorder . -
pubmed
We performed a cross - sectional study of 19
women aged 22 - 49 years , including 9
SLE patients in clinical remission taking & lt;=5 mg
prednisone and 10 matched controls . -
pubmed
Incubation of
human dopaminergic
SH - SY5Y cells with
amurensin G attenuated the cellular
toxicities of
rotenone in a model of
Parkinson ' s disease . -
pubmed
We report the case of a
patient with a history of recent
head trauma , who came to our observation for acute - onset mental
confusion secondary to severe
hyponatremia due to
SIADH of combined etiology . -
pubmed
In the research setting , some of these agents are combined in a single device , an approach that may become the standard treatment for many
patients with
chronic obstructive pulmonary disease . -
pubmed
A 54 - year - old
man with a left saphenous
varicose vein underwent EVLT surgery . -
pubmed
ANIMALS : Twenty - six client - owned
dogs : 15
dogs with clinical signs of
cervical hyperesthesia ( group 1 ) , and 11
dogs without of clinical signs ( group 2 ) . -
pubmed
RESULTS : All
dogs without clinical signs had symmetrical
syringomyelia , whereas in the group with
pain , 6
dogs had symmetrical and 9
dogs had asymmetrical
syringomyelia . -
pubmed
There was no significant difference between the mean width of the
syringomyelia in
dogs with or without
pain . -
pubmed
BACKGROUND : In ethno - medicinal practices , the roots of
Cissampelos pareira(
Patha ) are used in the treatment of various ailments related to urinary problems and
skin infections , and in tumorinhibitor activity , antibacterial , antimalarial , diuretic activity , anticonvulsant activity etc . -
pubmed
PATIENT SAMPLE : Of a consecutive series of 38
patients with
idiopathic thoracolumbar scoliosis ,
Lenke type 5 , 29
patients were included in the study . -
pubmed
This study collected
patients with
TC treated in 5 high - volume Italian Thoracic Surgery Institutions . -
pubmed
METHODS : A multicenter retrospective study of
patients operated for
TC between 2000 and 2011 was conducted . -
pubmed
RESULTS : Four hundred and seventy - eight
patients underwent surgery for
thymic malignancies : 40 of them ( 8.4 % ) had
TC . -
pubmed
Adjuvant radio / chemotherapy was offered to 37
patients , according to the type of surgical resection and
tumor invasiveness . -
pubmed
Recurrences developed in 10
patients . -
pubmed
Comparative pharmacokinetics of
borneol in
cerebral ischemia - reperfusion and sham - operated
rats . -
pubmed
METHODS : The
rats were divided into two groups ,
ischemia - reperfusion ( IR ) and sham - operated ( SO )
rats . -
pubmed
RESULTS : After administration of
borneol , the maximum plasma concentration ( Cmax ) and area under the curve ( AUC ) values in
stroke rats significantly increased by 302 % and 275 % , respectively , compared with the SO
rats , and the same phenomenon appeared after administration of XNJ . -
pubmed
Prophylactic effectiveness of
suplatast tosilate in
children with
asthma symptoms in the autumn : a pilot study . -
pubmed
METHODS : This study compared the prophylactic effectiveness of
suplatast tosilate with that of
mequitazine in
children with
asthma symptoms , which is usually exacerbated in the autumn . -
pubmed
The study group comprised 27
children aged 2 to 15 years who required treatment for
asthmatic attacks during the past year and tested positive at least for mite allergen in the preceding autumn . -
pubmed
Our aim was to examine the incidence , characteristics , reasons , and risk factors for unplanned revision surgery in
spinal deformity patients treated at one institution . -
pubmed
Epidemiological studies are weighted towards the presence of
BPH having a greater risk for a
man to develop
PCa in his lifetime ; however , a conclusion of causality can not be confidently stated . -
pubmed
Animal models of
poststroke fatigue (
PSF ) and
poststroke depression (
PSD ) would facilitate the study of these symptoms . -
pubmed
We used different
rat strains to evaluate
stroke - induced changes in behavior in hopes that interstrain differences would provide insights into the biological basis of these symptoms . -
pubmed
Male Lewis , Wistar , and
Sprague - Dawley ( SD ) rats underwent experimental
stroke . -
pubmed
Stroke also led to an increase in learned helplessness in Lewis
rats . -
pubmed
In summary , different patterns of behaviors emerge in different
rat strains after
stroke . -
pubmed
Diagnostic utility of F waves in clinically diagnosed
patients of
carpal tunnel syndrome . -
pubmed
METHODS : Median and ulnar nerves sensory and motor conduction , median and ulnar nerves F - wave studies were carried out bilaterally in 125 clinically diagnosed
patients of
carpal tunnel syndrome . -
pubmed
BACKGROUND : Pediatric and adult
anxiety disorder patients exhibit attention bias to threat and difficulty disengaging attention away from threat . -
pubmed
The aim of the present study was to examine the neural correlates of these processes in
children and
adolescents with
anxiety disorders . -
pubmed
METHODS :
Participants with an
anxiety disorder 7 to 19 years old ( n = 34 ) and typically developing controls ( n = 35 ) underwent fMRI scanning . -
pubmed
RESULTS : Analysis of ex vivo cultures from normal looking SQ from controls ,
RE patients , and
BE patients revealed no significant differences in the number and phenotypes of T - cells . -
pubmed
The recognition of
human papilloma virus (
HPV ) as the causal agent of
cervical cancer in the early 80 's changed the prevention paradigms . -
pubmed
Due to the existence in Chile of a well - organized nationwide
CC prevention program , the replacement of a low - sensitivity screening test such as the Papanicolau test with a highly sensitive one such as
HPV detection , could quickly improve the effectiveness of the program . -
pubmed
BACKGROUND : Delayed
hematoma expansion is common in
intracerebral hemorrhage (
ICH )
patients using
warfarin . -
pubmed
This study aims to clarify whether
dabigatran increases the risk of delayed
hematoma expansion in a
rat ICH model . -
pubmed
CONCLUSIONS : This experimental study of a
rat ICH model indicates that
dabigatran - related
ICH may not increase the risk of delayed
hematoma expansion . -
pubmed
We present a
patient with a
fistula that developed 23 years after hysterectomy and radiotherapy . -
pubmed
METHODS : Thirty
patients with early onset
chronic depression were compared with 30
patients with
episodic depression and 30 healthy , never -
depressed controls in terms of self - reported cognitive - behavioral ( social and non - social ) and emotional avoidance . -
pubmed
RESULTS : Chronically
depressed patients reported more avoidance than healthy controls in each of the measures . -
pubmed
Furthermore , general emotion avoidance and behavioral - social avoidance were positively correlated with levels of
depression in chronically depressed
patients . -
pubmed
METHODS : Clinical records of 14
outpatients and inpatients that visited the First Hospital of Jilin University ( Changchun , China ) for management of
burn injuries caused by cupping therapy were retrospectively reviewed . -
pubmed
We found that
TSA significantly inhibited lung
tumorigenesis in
Grg1 transgenic mice ( p & lt ; 0.01 ) . -
pubmed
Among the IHCIS patients 60 years of age or older and full year of eligibility during 2010 , there were 898
VaD patients , from which 63.6 % were women . -
pubmed
Concurrent presence of
cerebrovascular disease ,
atherosclerosis ,
heart failure , and
atrial fibrillation were found at 12.6 , 4.6 , 2.8 , and 1.7 times higher in
VaD patients , respectively . -
pubmed
METHODS : This was a prospective longitudinal study in
women with singleton pregnancies identified by screening at 11 + 0 to 13 + 6 weeks ' gestation as being at high - risk of
PE . -
pubmed
RESULTS : A total of 1069 samples were analyzed in 234
women , including 172 who remained normotensive , 18 who developed
GH , 22 who developed
preterm PE and 22 who developed term
PE . -
pubmed
Freshwater harmful algal blooms and
cyanotoxin poisoning in domestic
dogs . -
pubmed
Patients with occult lymph node
metastasis in
endometrioid - type endometrial cancer (
EC ) are prone to the development of
recurrences and have worse outcomes compared with
patients without lymph node
metastasis . -
pubmed
A univariate analysis of differentially expressed genes , proteins and clinicopathological parameters ( including myometrial invasion and
tumor grade ) was performed , comparing
EC patients with and without lymph node
metastasis ( n=262
patients from The Cancer Genome Atlas ) . -
pubmed
In addition , this compound also showed considerable protection against
pilocarpine induced
status epilepticus in
rats . -
pubmed
Vi conjugate
typhoid vaccine conferred 100 % protection against
typhoid fever in 1765
children 6 months to 12 years of age with high immunogenicity in a subgroup from the vaccine arm . -
pubmed
METHODS : In this phase 2 , single - blind , dose - ranging , adaptive randomised trial , we enrolled
boys and men with
uncomplicated P falciparum malaria at the Malaria Research and Training Centre ( MRTC ) field site in Ouelessebougou , Mali . -
pubmed
INTERPRETATION : A single dose of 0 25 mg / kg
primaquine , given alongside
dihydroartemisinin - piperaquine , was safe and efficacious for the prevention of
P falciparum malaria transmission in
boys and men who are not
deficient in G6PD . -
pubmed
This study examined whether
individuals with
rapid eye movement sleep behavior disorder who do not have a diagnosis of
PD show
abnormalities in gait initiation that resemble the impairments observed in
PD and whether there is a relationship between these deficits and the level of rapid eye movement sleep without
atonia . -
pubmed
METHODS : Gait initiation and polysomnography studies were conducted in 4 groups of 10
participants :
rapid eye movement sleep behavior disorder ,
PD with and without
freezing of gait , and controls . -
pubmed
CONCLUSIONS : These results provide evidence that
people with
rapid eye movement sleep behavior disorder , prior to a diagnosis of a
degenerative neurologic disorder , show alterations in the coupling of posture and gait similar to those seen in
PD . -
pubmed
In
patients with higher
weight gain at RRT initiation , mortality and dialysis dependency were significantly lower with continuous RRT ( HR 0.54 , 95 % CI 0.29 - 0.99 ; p = 0.05 ) . -
pubmed
Conversely , this technique appeared to be deleterious in
patients without
shock ( HR 2.24 , 95 % CI 1.24 - 4.04 ; p = 0.01 ) . -
pubmed
Six - month mortality and persistent
renal dysfunction were not influenced by the RRT modality in
patients with dialysis dependence at ICU discharge . -
pubmed
RESULTS : During follow - up ( median 119.0 , range 6.6 to 161.3 months ) ,
tumor recurrence was detected in 50
patients ( 43.1 % ) , and local
recurrence developed as a first failure site in 13
patients ( 11.2 % ) . -
pubmed
METHODS : We performed a retrospective study with 116 locally advanced
rectal cancer patients who underwent total mesorectal excision ( TME ) followed by postoperative concurrent chemo - radiation therapy ( CCRT ) . -
pubmed
METHODS : Adult
patients with isolated fresh unstable metacarpal and phalangeal
fractures who met the inclusion criteria were enrolled into this prospective study from July 2013 . -
pubmed
Animal models have implicated an integral role for coagulation factors in
neuroinflammatory diseases such as
multiple sclerosis (
MS ) beyond their role in hemostasis . -
pubmed
However , few researches compared the expression and functions of both oncogenes in
human malignant
tumors at same time . -
pubmed
This question is of crucial importance given the recent demonstration in both
animals and
humans that a period of
blindness early in life permanently affects the brain networks dedicated to visual , auditory , and multisensory processing [ 1 - 16 ] . -
pubmed
To address this issue , we compared a group of
adults who had been treated for
congenital bilateral cataracts during early infancy with a group of normally sighted controls on a task requiring simple detection of lateralized visual and auditory targets , presented alone or in combination . -
pubmed
However , in comparison to controls ,
cataract - reversal
patients were faster at processing simple auditory targets and showed differences in how they shifted attention across modalities . -
pubmed
In total , 30
children with
ASD ( mean age : 7.72 + - 2.65 y ; range ; 4 - 12 y ) and 30 healthy
children ( mean age : 8.4 + - 2.66 y ; range : 4 - 12 y ) , including males and females , were matched for age , gender , and
body mass index (
BMI ) . -
pubmed
We now show that this effect of T2S is also manifest upon
infection of
human THP-1 macrophages and peripheral blood monocytes but does not occur during
infection of
murine macrophages . -
pubmed
[ The modern possibilities for the treatment of the
patients presenting with benign and
tumour - like diseases of the larynx ] . -
pubmed
Rehabilitation of the
patients presenting with benign and tumour - like
diseases of the larynx (
BLT ) is currently a serious challenge for modern otorhinolaryngology in view of the high prevalence of this pathology . -
pubmed
Dysphonia is a leading clinical symptom of the diseases that considerably deteriorates the quality of life of the
patients . -
pubmed
The treatment of the
patients presenting with benign and tumour - like
diseases of the larynx requires a combined approach including the surgical , therapeutic , and phonopedic modalities for the rehabilitation of the vocal function . -
pubmed
This article presents a review of the literature on the modern high - energy techniques for the treatment of the
patients presenting with benign and
tumour - like diseases of the larynx , The advantages and disadvantages of each method are discussed . -
pubmed
The therapeutic potential of 177Lu - DTPA - sdAb was compared with that of 177Lu - DTPA -
rituximab and unlabeled
rituximab in
mice bearing hCD20pos
tumors . -
pubmed
Objective : To compare the degree of
pain relief between high - dose ( 40 mg of
triamcinolone acetonide ) and low - dose ( 20 mg of
triamcinolone acetonide )
corticosteroid injections in
patients with severe
pain due to
adhesive capsulitis . -
pubmed
Subjects : A total of 32
patients who were diagnosed with
adhesive capsulitis and who expressed severe
pain intensity , 8 or more points on a numeric rating scale ( NRS ) . -
pubmed
Conclusions : Injection of 20 mg of
triamcinolone acetonide is sufficient to elicit symptom relief in
patients with severe
adhesive capsulitis ; hence , 20 mg of
triamcinolone acetonide can be recommended in
patients with
adhesive capsulitis with severe
pain . -
pubmed
Hippocampal extracellular matrix alterations contribute to
cognitive impairment associated with a chronic
depressive - like state in
rats . -
pubmed
Patients with
depression often suffer from
cognitive impairments that contribute to disease burden . -
pubmed
We used social defeat - induced persistent stress ( SDPS ) to induce a
depressive - like state in
rats and then studied long - lasting
memory deficits in the absence of acute stressors in these
animals . -
pubmed
Our data reveal a causal link between increased hippocampal extracellular matrix and the
cognitive deficits associated with a chronic
depressive - like state in
rats exposed to SDPS . -
pubmed
Introduction :
Acute respiratory distress syndrome (
ARDS ) is a devastating pulmonary condition in the
critically ill patient . -
pubmed
RESULTS : Of 100 included
patients , ten ( median GA 27.5 weeks [ 24.6 - 29.4 ] , BW 1010 g [ 775 - 1630 ] ) developed
NEC . -
pubmed
A 49 - year - old
woman was admitted to our hospital with recurrent episodes of
paresthesia attacks evolving in 5 to 15 minutes from the left hand to the left leg through the left trunk . -
pubmed
Because we assumed the cause of the recurrent sensory attack to be
meningeal inflammation around the primary somatosensory cortex , we treated this
patient by increasing the dose of
prednisolone . -
pubmed
OBJECTIVES : The aim of this study was to compare skeletal maturity between the groups depending on the
malocclusion as well as to define the optimal timing for particular orthodontic treatment procedures in
children with miscellaneous types of
malocclusion and compare it with the duration of treatment proposed by the National Health Fund ( NFZ ) . -
pubmed
Vehicle- or
ethanol- ( 1.6 g / kg ) treated
mice were subjected to sham or 15 % total body surface area scald
burn . -
pubmed
Taken together , our results suggest intravenous MSCs treatment can diminish systemic
inflammation , lessen
hepatic damage , and decrease liver and lung apoptosis and
inflammation , indicating MSCs as a novel therapy for restoring homeostasis of multiple organ systems in intoxicated
burn patients . -
pubmed
RESULTS : Most
children with midline spikes had
seizures ( 91 % ) , with an equal predisposition to focal or generalized
seizure semiology . -
pubmed
In
patients with abnormal neuro - maging ,
deep gray or white matter abnormalities were more frequent in the midline group ( 41 % vs. 13 % , P = 0.02 ) . -
pubmed
The genome revealed that the G+C content was 63.9 mol% and the DNA - DNA relatedness values between
strain WN007 T and the type
strains of
P. - pubmed
Targeted Diet Modification Reduces
Multiple Sclerosis - like Disease in Adult
Marmoset Monkeys from an Outbred Colony . -
pubmed
Experimental
autoimmune encephalomyelitis (
EAE ) in common
marmosets is a translationally relevant model of the chronic
neurologic disease multiple sclerosis . -
pubmed
The reduced
EAE susceptibility after the dietary change coincided with reduced
Callitrichine herpesvirus 3 expression in the colony , an
EBV - related gamma1 - herpesvirus associated with
EAE . -
pubmed
Spinal cord demyelination , a classical hallmark of the disease , was significantly lower in new - diet
monkeys than in
monkeys reverted to the original diet . -
pubmed
2 '- fucosyllactose (
2 - FL ) , one of the most abundant
human milk
oligosaccharides ( HMOs ) , has received much attention due to its health - promoting activities , such as stimulating the growth of beneficial gut microorganisms , inhibiting
pathogen infection , and enhancing the host immune system . -
pubmed
Dexmedetomidine Ameliorates
Sleep Deprivation - Induced
Depressive Behaviors in
Mice . -
pubmed
In this study , the action of
dexmedetomidine on
sleep deprivation - induced
depressive behaviors was investigated using
mice . -
pubmed
METHODS : For the inducing of
sleep deprivation , the
mice were placed inside a water cage containing 15 platforms and filled with water up to 1 cm below the platform surface for 7 days . -
pubmed
One day after
sleep deprivation ,
dexmedetomidine at the respective dosage ( 0.5 , 1 , and 2 mug / kg ) was intraperitoneally treated into the
mice , one time per a day during 6 days . -
pubmed
The
patient was asymptomatic and therefore continued on to chemotherapy treatment for the large
B - cell lymphoma . -
pubmed
BACKGROUND : The added value of cardiopulmonary exercise testing ( CPET ) in the follow - up of
patients with stable
pulmonary arterial hypertension (
PAH ) remains undefined . -
pubmed
METHODS : Idiopathic , heritable , and drug - induced
PAH patients free from clinical worsening ( CW ) after 1 year of treatment were enrolled in derivation ( n = 80 ) and validation ( n = 80 ) cohorts at an interval of 6 years and followed for 3 years . -
pubmed
CONCLUSIONS : The combinations of baseline VO2 peak and change in CI during follow - up is important in prognostication of low - risk
patients with idiopathic , heritable , and drug - induced
PAH . -
pubmed
OBJECTIVE : To present the essential guidelines for pharmacological management of
patients with
psychomotor agitation in Brazil . -
pubmed
METHODS : We are presenting the case of a 62 - year - old male
patient suffering from 63 - mm
juxtarenal aortic aneurysm . -
pubmed
Inflammatory responses and biological characteristics of
human osteosarcoma cells and umbilical cord blood mononuclear cells in co - cultured microenvironment . -
pubmed
Moreover , the results indicated that these two evaluation methods enabled more accurate determination of severity and the spared capabilities of
AD patients . -
pubmed
To better understand the influence of crossover dynamics on WNV transmission , we examined environmental and mosquito abundance data , as well as
mosquito infection rates and
human disease cases from 2016 to 2018 . -
pubmed
Therefore , the purpose of this study is to elucidate the role of the multifidus ( MF ) and psoas major ( PS ) muscles in maintaining global spinal alignment in
patients with
lumbar spinal stenosis (
LSS ) and/or
degenerative spondylolisthesis (
DS ) , and to analyze whether each muscles ' cross - sectional area ( CSA ) correlates with whole - body SMM using bioimpedance analysis ( BIA ) . -
pubmed
METHODS : We retrospectively evaluated 140
patients who were hospitalized for surgery to treat
LSS and/or
DS . -
pubmed
BACKGROUND : The rate of
thyroid cancer in
patients with
hyperthyroidism is reported to be rare , and patients with toxic
thyroid nodules do not routinely undergo fine - needle aspiration ( FNA ) to evaluate for
malignancy . -
pubmed
However , higher rates of
malignancy in
hyperthyroid patients may exist than previously reported . -
pubmed
This study examines the rate of
malignancy in
patients with
hyperthyroidism who have undergone thyroidectomy . -
pubmed
METHODS : A retrospective review of prospectively collected data of 138
patients with
hyperthyroidism who underwent thyroidectomy at a single institution was performed . -
pubmed
Patients were divided into three groups :
Graves ' disease ( n = 80 ) ,
toxic multinodular goiter ( n = 46 ) , and toxic solitary nodule ( n = 12 ) . -
pubmed
RESULTS : Of 138
patients , 22 % ( 31/138 ) were found to have
malignancy on final pathology . -
pubmed
The breakdown of
malignancy by
hyperthyroid condition was as follows : 16 % in
Graves ' disease , 24 % in
toxic multinodular goiter patients , and 50 % in toxic solitary nodule patients . -
pubmed
CONCLUSIONS : There is a clinically significant rate of
malignancy seen in
patients who undergo thyroidectomy for
hyperthyroidism . -
pubmed
Patients with distinct
thyroid nodules in the presence of
hyperthyroidism may have the highest rates of
malignancy and should undergo appropriate workup with ultrasound and FNA to exclude underlying
malignancy . -
pubmed
Transcranial direct current stimulation in
patients with
obsessive compulsive disorder : A randomized controlled trial . -
pubmed
Neuroimaging studies have identified dysfunctions within the orbito - fronto - striato - pallido - thalamic network in
patients with
OCD . -
pubmed
METHODS : In a randomized sham - controlled double - blind study , 21
patients with
OCD were assigned to receive ten 20 - min sessions ( two sessions per day ) of either active ( 2 mA ) or sham tDCS . -
pubmed
BACKGROUND :
Metastatic castration - resistant prostate cancer (
mCRPC ) is incurable , with most
patients surviving less than 3 years . -
pubmed
OBJECTIVE : To describe the
patient demographics , disease characteristics , treatment patterns , and outcomes in a cohort of Veterans diagnosed with
mCRPC in the Veterans Health Administration . -
pubmed
Following
mCRPC diagnosis , the most common first - line therapies in Epoch 1
patients were
docetaxel ( 83 % ) and
abiraterone ( 9 % ) , whereas Epoch 2
patients mainly received
abiraterone ( 47 % ) ,
docetaxel ( 36 % ) , and
enzalutamide ( 15 % ) . -
pubmed
The
tumor inhibition efficiency of DiLNs in combination with immune checkpoint inhibitor antibody was studied in syngeneic
D4 M animal model . -
pubmed
Comparison between the
toxicity profile of
fluorouracil versus
capecitabine concomitant with radiotherapy in
patients with
non - metastatic rectal cancer . -
pubmed
High proportion of unknown
HIV exposure status among children aged less than 2 years : An analytical study using the 2015 National
AIDS Indicator Survey in Mozambique . -
pubmed
BACKGROUND : Determination of the
human immunodeficiency virus (
HIV ) exposure status in infants and young children is required to guarantee timely diagnosis and access to appropriate care . -
pubmed
Prophylaxis treatment of
COVID-19 patients with
low molecular weight heparin ( LMWH ) is important to limit
coagulopathy . -
pubmed
A report of probable
paroxysmal sympathetic hyperactivity syndrome in a
patient with
necrotizing fasciitis . -
pubmed
VAL ,
DIC ,
MEL ,
VAL +
MEL and
VAL +
DIC produced anticonvulsant effect and mitigated
inflammation and oxidative stress in
PTZ - kindled
mice . -
pubmed
PURPOSE :
Patients with
Graves ' orbitopathy can present with asymmetric disease . -
pubmed
New
patients presenting over a 4 month period with a diagnosis of
Graves ' orbitopathy were included . -
pubmed
Patients were categorized as having asymmetric , symmetric , and unilateral
Graves ' orbitopathy . -
pubmed
Sudden Cardiac Arrest and
Malignant Ventricular Tachycardia in an 8 - Year - Old Pediatric Patient Who Has
Hemolytic Uremic Syndrome Associated with Shiga Toxin - Producing
Escherichia coli . -
pubmed
Gastrointestinal , neurological , pancreatic , hepatic , and
cardiac dysfunction are extrarenal manifestations of
hemolytic uremic syndrome associated with Shiga toxin - producing
Escherichia coli ( STEC -
HUS ) . -
pubmed
Comparative analysis of presentation and outcome after liver resection of
patients with
hepatocellular carcinoma with and without HIV . -
pubmed
OBJECTIVE : Evidence shows that
HIV infection may affect the survival outcome of
patients with
hepatocellular carcinoma (
HCC ) . -
pubmed
Here , we aimed to determine whether
HIV affected the overall survival ( OS ) of patients with
HCC in China and ascertain the risk factors . -
pubmed
The
death rate due to
tumor recurrence and
liver failure in the
HIV - positive
patients were apparently higher than those of the
HIV - negative
patients (
tumor recurrence , 42.3 % vs. 17.3 % , P = 0.016 ;
liver failure , 19.2 % vs. 2.7 % , P = 0.012 , respectively ) . -
pubmed
CONCLUSIONS :
HIV - positive subjects with
HCC have poorer survival outcome than their HIV - negative counterparts , with
tumor recurrence and
liver failure as the main causes of
death . -
pubmed
Despite adequate curative therapy ,
HIV serostatus is associated with decreased survival of
patients with
HCC , independent of symptomatic presentation ,
tumor staging , and liver function . -
pubmed
METHODS : Our
trauma registry was reviewed for
patients with a
hemothorax admitted to our level 1
trauma center from 1/1/00 to 4/30/19 . -
pubmed
Patients were included in the delayed group if they received a drainage procedure > 24 hours after
injury . -
pubmed
These
patients were matched 1:1 by chest abbreviated
injury score to
patients who received drainage < 24 hours from
injury . -
pubmed
RESULTS : A total of 19
patients with 22
hemothoraces received delayed drainage . -
pubmed
The polarization of monocytes into macrophages that possess anti - inflammatory and pro - angiogenic properties could provide a novel therapeutic strategy for
patients who are at a high risk for developing
heart failure following
myocardial infarction (
MI ) . -
pubmed
METHODS : Forty - one and 49 consecutive
atrial fibrillation patients underwent 2nd - CB and 4th - CB PVIs using 28 - mm balloons and short freeze strategies . -
pubmed
During the replication a pathogenic and a non - pathogenic
strain of
mouse cytomegalovirus in
mouse embryo cells , three types of progeny virus particles were observed in both cases ; the virus yields of the two
strains differed considerably . -
pubmed
The main purpose of our experimental series was to induce , in experimental animals , diffuse
pulmonary fibrosis resembling that in
human lungs . -
pubmed
Fourteen
children with
viral infection of the central nervous system have been examined with respect to their function of humoral immunity . -
pubmed
These three
children showed complications in the course of
infection . -
pubmed
Corneocytes from skin of
patients with
allergic contact dermatitis differed from those of normal skin : they were 15 % smaller and of irregular shape with asymmetrical trabeculae ; 50 % were nucleated and about 3 times as many cells were collected per cm2 skin surface . -
pubmed
In naive
rats depression of spontaneous discharge activity was the predominant effect of low doses of phoretically applied
morphine . -
pubmed
Correlation of detection of infectious DNA - protein complexes with persistence of virus in
simian adenovirus SA7 - induced
tumor cells . -
pubmed
Primary tumors induced in newborn
hamsters by
simian adenovirus SA7 were investigated in transfection experiments . -
pubmed
SA7 tumor cells serially passaged either in tissue culture or in
hamsters yielded infectious DNA complexes much less frequently and appeared to evolve into
nonyielder cell lines . -
pubmed
These inhibitor(s ) are found in
ascites from
ovarian cancer patients and are detected in very low amounts in the
ascites from
patients with nonmalignant
hepatic disease . -
pubmed
The method described appears promising in terms of efficiency , reduction in the costs and technical procedures during treatment of
human infertility . -
pubmed
From genes to antibodies : the antipeptide approach to the immunocytochemical study of
human malignant lymphoproliferative diseases . -
pubmed
PURPOSE : To evaluate immediate postoperative results in
children with
congenital heart disease and decreased pulmonary blood flow who underwent a systemic to pulmonary shunt . -
pubmed
Mitral balloon valvotomy using the Inoue balloon technique for selected
patients with severe pliable
rheumatic mitral valve stenosis : immediate and short - term results . -
pubmed
We selected 40
patients with severe symptomatic
rheumatic mitral stenosis for balloon valvotomy using the Inoue balloon technique . -
pubmed
Five
patients developed mild
mitral regurgitation and in one patient the degree of
mitral regurgitation increased from mild to moderate . -
pubmed
The resurgent
strain , designated
A / USSR / 90 / 77(H1N1 ) , caused world pandemics , attacking ( almost exclusively ) persons who had been born since the 1950 - 1951 northern winter and causing negligible mortality . -
pubmed
MAIN OUTCOME MEASURE : The
A / USSR / 90 / 77 strain and its close successor ,
A / Brazil / 11 / 78 , attacked mainly the young , whose previous exposure to H1N1 antigens had been minimal or zero . -
pubmed
Sixteen
patients were considered to have moderate to severe
brain lesions . -
pubmed
One
patient suffered a right temporal
hemorrhage following cannulation of the left common carotid artery . -
pubmed
To analyze left atrial ( LA ) pump function in normal subjects , in
patients with essential
hypertension and in
patients with a healed
myocardial infarction , LA dimension ( aortic - root echogram ) and pressure ( catheter - tip manometer ) were simultaneously recorded in 25
patients ( 8 normal subjects , 7 with
hypertension and 10 with
myocardial infarction ) . -
pubmed
Prodromal symptomatology was investigated , by means of a modified version of Paykel 's Clinical Interview for
Depression , in 15
outpatients at their first episode of primary
major depressive disorder . -
pubmed
Poisoning from
Thevetia nerifolia (
yellow oleander ) -
pubmed
Renal artery stenosis in
patients with
aortic dissection : increased prevalence . -
pubmed
The authors retrospectively analyzed the prevalence of
renal artery stenosis in 63 consecutive
patients with
aortic dissection who underwent thoracic and abdominal aortography . -
pubmed
Ten
patients ( 16 % ) had
renal artery stenosis , five with
atherosclerosis and five with
fibromuscular lesions . -
pubmed
In this series , emergent PTRA successfully controlled the
hypertension in one
patient with a
type B dissection , resulting in an excellent clinical outcome . -
pubmed
Angiography should be routinely performed on
patients with
aortic dissections to evaluate for
renal artery stenosis . -
pubmed
Not all
patients with
supraventricular arrhythmias require invasive studies , however , since empiric drug trials will often be adequate for management . -
pubmed
Innovations that include surgical and catheter ablations of
tachycardia pathways and antitachycardia pacing devices hold great promise and in the future , will provide nonpharmacologic options for
patients poorly controlled by or intolerant of drug therapy . -
pubmed
A
girl presenting with an
enlargement of the spleen ,
thrombocytopenia and
microangiopathic hemolytic anemia at birth was studied , and a
splenic hemangioma was diagnosed . -
pubmed
The authors report the radiological features of a
patient , believed to be unique in the literature , of multiple
aneurysms of the lateral - most lenticulostriate artery in a normotensive , non - diabetic , young , female
patient who presented with left basal ganglionic
hematoma and showed spontaneous obliteration of these
aneurysms , on follow - up angiography . -
pubmed
The long - term antihypertensive activity and acceptability of a new beta - blocking agent
tertatolol ( T ) ( 5 mg once daily ) was assessed in a 12 - month ( M0 - M12 ) open study , in 110 out -
patients ( 64
men , 46
women , mean age 53.5 + /- 1.0 years ) , presenting with stable placebo - resistant
hypertension (
HT ) ( 95 less than or equal to diastolic blood pressure less than 130 mm Hg on 3 occasions during a 1 - month placebo run - in period ) . -
pubmed
The older
child undergoing intermediategrade surgery requires the best available analgesia , but without sedation and
nausea . -
pubmed
The advantages of both these methods are then available for the benefit of the
child , and the value of regional analgesia is further enhanced when supplementary intramuscular or oral analgesia is given regularly at specific times so that
pain is prevented rather than relieved . -
pubmed
[ 56 - year - old
man with the clinical picture of
intestinal obstruction ] . -
pubmed
[ Kidney echo scanning in
patients with
chronic kidney failure ] . -
pubmed
Pulmonary emboli in burned
patients . -
pubmed
The incidence of and prophylaxis against clinically important
pulmonary emboli (
PE ) in burned
patients is an often discussed problem . -
pubmed
To study its magnitude , all
patients admitted with acute
burns were followed for clinical evidence of
thromboembolism : 2,106
patients were evaluated ( 1,439 adults ) . -
pubmed
Six
adults ( 0.4 % ) sustained a
PE : none died . -
pubmed
Only two
patients had significant risk factors ; they were
obese with leg
burns . -
pubmed
The incidence of
pulmonary emboli and resulting morbidity do not justify routine prophylactic heparinization of all burned
patients . -
pubmed
It was detected 5 years later when the
patient developed persistent
low back pain . -
pubmed
Effect of maternal vaccination on the susceptibility of growing
pigs to
leptospiral infection . -
pubmed
Twelve
pigs , 4 derived from unvaccinated sows and 8 from sows vaccinated against
leptospirosis , were challenged intravenously at 8 weeks of age with leptospires of
serovar pomona . -
pubmed
All of the
pigs derived from unvaccinated sows developed
leptospiraemia and
leptospiruria and showed strong serological responses . -
pubmed
In a prospective series of 66
patients with
uretero - pelvic stenosis ( " genuine
hydronephrosis " ) the clinical data and the results of treatment were registered . -
pubmed
At 7 days after MRMT-1 inoculation at the thigh of 5 week - old female SD
rats , the
tumor was treated cryosurgically by 2 cycle freezing , contact method at -170 degrees C. Weights of thymus and the spleen , histological findings of lumbar lymph nodes , PHA - induced blastogenesis of lymphocytes obtained from lumbar lymph nodes or peripheral blood , and resistance rate to
tumor re - challenge were examined at 1 , 3 , 6 , 10 and 17 week(s ) after cryosurgery . -
pubmed
When
human diploid fibroblasts ,
TIG-1 , reached the end of their proliferative lifespan in vitro , they still could synthesize proteins with molecular weight of about 70,000 , 85,000 and 116,000 following the heat
shock at 46 degrees C for 10 min as well as young cells did so . -
pubmed
Lack of correlation between occlusion and reperfusion
arrhythmias in the
cat . -
pubmed
Recently it has been stated that in
dogs absence of
arrhythmias during
coronary artery occlusion identifies a subgroup at almost no risk for developing
ventricular fibrillation (
VF ) during reperfusion . -
pubmed
In order to reexamine this problem the left anterior descending coronary artery was occluded for 20 minutes in 41 anesthetized
cats ; the incidence and type of
arrhythmias during occlusion and during the first minute of reperfusion were analyzed . -
pubmed
Five
animals had
VF during occlusion and were not resuscitated . -
pubmed
Twenty
animals had
ischemic arrhythmias , and among them the incidence of reperfusion
VF was 50 % . -
pubmed
Sixteen
animals did not have
ischemic arrhythmias , but they did have a very similar incidence of reperfusion
VF ( 44 % ) . -
pubmed
It has been shown in experiments on white male
rats that there is a correlation between
hypoxia tolerance and the rate of metabolism in brain tissue . -
pubmed
Animals with varying tolerance to
hypoxia differed also in the acid - base balance of venous blood outflowing from the brain . -
pubmed
While adapting to
hypoxia animals with high individual tolerance developed the main metabolic changes in the reticular formation and those with low tolerance in the cerebral cortex . -
pubmed
During adaptation to
hypoxia animals with high and low tolerance had varying changes in acid - base balance . -
pubmed
The data obtained allow the conclusion that there is a correlation between the rate of brain tissue metabolism , acid - base balance of jugular vein blood and individual
animals ' tolerance to
hypoxia . -
pubmed
Distribution of
calcium and
magnesium in
rat kidney homogenate fractions accompanying
magnesium deficiency induced
nephrocalcinosis . -
pubmed
Comparative evaluation of
potato diploids ,
tetraploids , and chimerae periclinal with respect to ploidy . -
pubmed
[ Induction of gastrointestinal
hemorrhages in the
rat by
acetylsalicylic acid and
acetylsalicylic acid - containing drugs ] . -
pubmed
Fluorouracil : mechanism of action in
human skin and
actinic keratoses . -
pubmed
Plasma
tocopherol concentrations and
vitamin E deficiency in
dogs . -
pubmed
Two groups of
patients with
transient ischaemic attack and
minor stroke without detectable haemodynamic stenotic lesions were evaluated by neuropsychological tests and compared with a control group . -
pubmed
The mean values of the scores adjusted for age and educational background demonstrated that the
patients with
transient ischaemic attack did not have a worse performance than normal subjects in any of the tests , the
patients with
minor stroke had a worse performance than normals , particularly in Rey 's figure - copying test ( P less than 0.025 ) , and the latter test was not affected by educational background or age of the subjects . -
pubmed
We analyzed mononuclear leukocytes from
patients with various
human leukemias by high - resolution two - dimensional electrophoresis . -
pubmed
Postmortem studies of six
patients , four with documented
optic nerve lesions , are presented . -
pubmed
After intrapleural instillation of talc for
sclerosis of
malignant pleural effusions ,
dyspnea occurred in three
patients , progressed gradually over 72 hours , and culminated in acute
respiratory failure characterized by bilateral diffuse pulmonary infiltrates with normal
pulmonary artery occlusion pressures . -
pubmed
When
talc is used in
patients who are unresponsive to
tetracycline , we suggest clinical monitoring for
respiratory compromise for 72 hours after the procedure . -
pubmed
Infection was verified in 23
patients ( mean gestational age 32 weeks and mean
body weight 2100 g ) and clinical cure or marked improvement occurred in 20 of these . -
pubmed
Of the remaining 3
patients , 2 died , partly due to reasons unassociated with
infection . -
pubmed
Fifty - one
patients with metastatic
breast cancer were randomly allocated to receive either a four drug combination consisting of
cyclophosphamide ,
methotrexate ,
5 - fluorouracil , and
prednisone (
CMFP ) , or a combination of
vincristine ,
Adriamycin , and
cyclophosphamide (
VAC ) with cross - over on
relapse . -
pubmed
1 The blood
pressure lowering effect of
xipamide , a non -
thiazide diuretic given for 6 weeks was compared in a randomised cross - over trial with that of
cyclopenthiazide in 14
patients with essential
hypertension . -
pubmed
4 These results suggest that 10 mg or 20 mg of
xipamide daily is effective in lowering blood pressure in
hypertensive patients but is associated with
hypokalaemia . -
pubmed
In view of recent evidence linking diuretic - induced
hypokalaemia with
cardiac dysrhythmias in
patients with essential
hypertension we would suggest that
thiazide diuretics be used in preference to
xipamide for the routine management of essential
hypertension . -
pubmed
Twelve
patients were followed up 6 - 40 months after implantation of a velours prosthesis due to
trauma involving the clavicle . -
pubmed
On the X - rays of the ten
patients with a coracoclavicular loop there was a marked
bone erosion in the area where the graft crossed the clavicle , and three patients had clinical symptoms as well . -
pubmed
Adults developed various
tachycardias (
tachyarrhythmias ) compared to severe
sinus bradycardias in the newborns . -
pubmed
In conclusion , the newborn
rat is much more sensitive to
digoxin toxicity than the adult as demonstrated by ECG criteria . -
pubmed
Several
individuals possessing the variant exhibited mild
anemia . -
pubmed
Effect of
vitamin B6 deficiency on in vitro uptake and metabolism of
pyridoxine x HCL by
rat jejunum . -
pubmed
METHODS :
Sprague - Dawley rats developed
cirrhosis with
ascites approximately 20 weeks after weekly intragastric instillation of
carbon tetrachloride . -
pubmed
OBJECTIVE : To assess the development and cause of
malabsorption in
rhesus macaques following experimental
simian immunodeficiency virus ( SIV ) infection and to evaluate its impact on nutritional status . -
pubmed
DESIGN : Clinical malabsorption tests and serial jejunal aspirates and biopsies were obtained from nine
SIV - infected and three uninfected animals prior to
infection and at 1 , 2 , 4 , 8 , 12 , 24 , 40 and 52 weeks postinoculation . -
pubmed
Bacterial overgrowth was not considered to be a cause of
malabsorption . -
pubmed
The high proportion of
macaques experiencing
malabsorption without detectable pathogens , suggests an enteropathogenic role for
SIV . -
pubmed
Renal cell carcinoma in
children : a single institution 's experience . -
pubmed
Seven
patients with
renal cell carcinomas (
RCC ) were treated at the Department of Pediatric Oncology in Prague over a period of 15 years . -
pubmed
Four
patients are without evidence of
disease with a minimal follow - up period of 2 years . -
pubmed
One
patient died of
tumor emboli to the lungs at operation . -
pubmed
Tumor diagnosis and treatment of the
patients in the lower clinical stages seem to have a favorable prognostic impact in childhood
RCC . -
pubmed
We have recently shown that brain temperature can drop even though rectal and skull readings are maintained near 37 degrees C during global
forebrain ischemia in the
gerbil . -
pubmed
In this study
gerbils were subjected to 5 min of
ischemia followed by 85 min of extended
halothane anesthesia , while rectal and skull temperatures were kept at normal values . -
pubmed
Ictal SPECT provides unique information for the clinician treating
patients with
refractory epilepsy and reveals insights into the pathophysiology of
seizures . -
pubmed
We have devised and implemented techniques for rapid reconstitution of
99mTc - HMPAO adjacent to the video - EEG monitoring suite such that the tracer can be rapidly injected into
patients when spontaneous
seizures occur . -
pubmed
The clinical results in
patients with
temporal lobe epilepsy show that ictal injections ( 97 % correct lateralization of focus , 0 % incorrect ) are more sensitive and accurate compared to interictal studies ( 48 % correct , 10 % incorrect ) , demonstrating that the implementation of these techniques is worthwhile . -
pubmed
RESULTS : Thirteen
women and 6
men in this incidence cohort of
PMR had & gt ; or = 1 episode of distal extremity
swelling with pitting
edema . -
pubmed
Giant cell arteritis was also identified in 5
patients . -
pubmed
In 11
patients , the
swelling and
edema development concurrently with proximal
PMR symptoms . -
pubmed
In 2
patients , the distal
swelling was the initial manifestation , and in 6
patients , the distal symptoms developed during
relapses or
recurrences of
PMR . -
pubmed
Audiogenic seizures following global
ischemia induced by
chest compression in Long - Evans
rats . -
pubmed
Transient global
ischemia was used to produce a
rat model of generalized
tonic - clonic epilepsy . -
pubmed
Controlled chest compression in
ketamine - anesthesized Long - Evans
rats produced transient global
ischemia by mechanically preventing the heart from pumping blood . -
pubmed
With a temporal muscle ( skull ) temperature of 35 + /- 0.4 degrees C , 75 % ( 76/102 ) of the
rats survived 7 min of
chest compression . -
pubmed
Generalized
seizures could be evoked in 78 % ( 59/76 ) of the surviving
rats by a 60 s exposure to a loud sound ( bell , 110 dB ) beginning 24 h after the
ischemic episode . -
pubmed
The
seizure patterns seen resembled those described by Maresceaux ( 1987 ) for genetically
seizure - prone
Wistar rats . -
pubmed
Susceptibility to sound - induced
seizures declined with time , with wide variations in recovery rate between
individuals ; one
rat showed a daily sound - induced
seizure for over 5 months . -
pubmed
Mometasone furoate aqueous nasal spray ( Nasonex ) was compared with
beclomethasone dipropionate (
BDP ) aqueous nasal spray in a double - blind , randomized , placebo - controlled , double - dummy , parallel - group study of
adults with moderate to severe
seasonal allergic rhinitis . -
pubmed
Patients allergic to at least one tree and/or
grass aeroallergen received one of the following regimens for up to 4 weeks ;
mometasone furoate 100 micrograms once daily [ OD ] ( n = 126 ) or 200 micrograms OD ( n = 126 ) ,
BDP 200 micrograms twice daily ( n = 126 ) , or only placebo spray ( n = 123 ) . -
pubmed
Stimulation of neonatal
mouse calvarial
bone resorption by the glucocorticoids
hydrocortisone and
dexamethasone . -
pubmed
We developed a novel and efficient cDNA subtraction method to isolate
rat hepatocellular carcinoma (
HCC)-related genes . -
pubmed
The
SPs were found both in the hippocampus and frontal cortex while NFTs were seen only in the hippocampus in non - demented aged
individuals . -
pubmed
The combination of genotypic analysis and new treatment methods offers exciting new prospects in the management of
patients with
cutaneous lymphoma . -
pubmed
Such
strains were selected from 344
human rotavirus strains recovered in palermo during those years after characterization by electropherotyping , subgrouping and G serotyping . -
pubmed
RESULTS : The modified CRM was used in two dose - finding trials of
9 - aminocamptothecin in
patients with newly diagnosed and recurrent
glioblastoma who were taking anticonvulsant medication . -
pubmed
Influence of computed tomography on pretherapeutic
tumor staging in
head and neck cancer patients . -
pubmed
Refinements in radiographic techniques have resulted in increased use of radiographic studies in the evaluation of
patients with
head and neck cancer over the past 20 years . -
pubmed
In colony formation assays against the
human head and neck
squamous carcinoma cell line
SCC25 after 72 h of treatment , the
5 - and 8 - deaza analogues were approximately as potent as 3 , whereas the
5,8 - dideaza analogue was 3 times more potent . -
pubmed
The
5 - methyl-5 - deaza analogue of 3 was also tested at the National Cancer Institute against a panel of 50
human tumor cell lines in culture and was consistently more potent than 3 , with IC50 values in the low - nanomolar to subnanomolar range against most of the
tumors . -
pubmed
Its differential expression has been documented in various
human tumours . -
pubmed
h-1 , respectively ; n=30 ) ,
type IIa hyperlipidemic patients ( 4 . -
pubmed
h-1 , respectively ; n=36 ) , and
type IIb hyperlipidemic patients ( 3.90+/-0.79 mg / L and 575+/-48 nmol . -
pubmed
PATIENTS : Infertile
women with different stages of
endometriosis who were treated by laparoscopic surgery , with a mean duration of
infertility of 80.7 ( + /-50 [ SD ] ) months . -
pubmed
INTERVENTIONS :
Patients were treated by cauterization of the foci , adhesiolysis ,
endometrioma stripping , and distal tubal reconstruction according to their lesions . -
pubmed
MAIN OUTCOME MEASURE : Cumulative pregnancy rate of infertile
women after laparoscopic treatment of
endometriosis with or without ovulation induction . -
pubmed
In the present study HD-03 , a herbal formulation was investigated for its anti -
cholestatic activity in
TAA - induced
cholestasis in anaesthetized
guinea pigs . -
pubmed
We investigated 1 , 042 consecutive
patients who had first
strokes , during a period of 5 years ( from June 1992 to May 1997 ) and classified them prospectively based on etiopathogenic mechanisms . -
pubmed
Patients with
transient ischemic attacks and
subarachnoid hemorrhage were excluded . -
pubmed
Forty - six percent of the
patients arrived within 3 h from
stroke onset . -
pubmed
Study of acute
chagasic mice under immunosuppressive therapy by
cyclosporin A : modulation and confocal analysis of inflammatory reaction . -
pubmed
The in vivo effects of
cyclosporin A (
CsA ) on
Trypanosoma cruzi infection were examined using different schedules of the drug in
mice infected with the Y
strain . -
pubmed
Parasitaemia at day 8 after
infection among
CsA - treated animals was usually higher than control infected non - treated
mice . -
pubmed
The mean time of
death in the animals treated with 200 mg / kg 5 days after
infection and in infected non - treated control
mice were respectively 29.0 and 22.6 days . -
pubmed
The kinetics analysis of the leukocyte population of animals treated with a single dose of 200 mg / kg of
CsA before or after
infection did not show the alternate pattern of
leukopenia /
leukocytosis observed in control groups of infected
mice but differential cell counts indicated a modulatory action upon circulating leukocytes of therapeutic doses of
CsA. -
pubmed
METHODS : We compared cardiothoracic ratio ( CTR ) , left ventricular ejection fraction ( LVEF ) from radionuclide ventriculography , and left ventricular dimensions from echocardiography in a population of 91
patients ( aged 60.4 ( SD 9.6 ) years ) with a diagnosis of chronic
heart failure . -
pubmed
We have observed 2 cases of
eczema herpeticum among 36
patients with
atopic dermatitis treated with a topical preparation containing 0.1 %
tacrolimus . -
pubmed
The lesions resolved quickly under intravenous
acyclovir treatment but resulted in important
facial scarring in the male
patient . -
pubmed
Depression in
stroke patients 7 years following
stroke . -
pubmed
OBJECTIVE : To study the frequency of
depression in
stroke patients many years following
stroke , most previous studies having concentrated on the first few years . -
pubmed
METHOD : Participants of a previous study of
post - stroke depression ( 99
stroke patients and 28 control
subjects ) were re - examined 7 years later . -
pubmed
RESULTS : Twenty per cent of the
stroke patients fulfilled the criteria for major or minor
depression compared with 11 % of the control subjects . -
pubmed
No differences in cognitive function were found between depressed and non - depressed
stroke patients . -
pubmed
The
stroke patients reported experiencing more lability of mood and
irritability during the 7 - year period following
stroke than the control subjects . -
pubmed
Depressed stroke patients experienced more
impairment of concentration and memory function than non - depressed
stroke patients . -
pubmed
CONCLUSION : Affective symptoms are common among
stroke patients 7 years following
stroke . -
pubmed
Although the findings are similar , a postpartum uterus ,
lymphoma , and a
bleeding uterus caused pelvic
FDG uptake in these
patients . -
pubmed
Interestingly , of these three
patients , the
patient with
lymphoma had the lowest level of
FDG uptake . -
pubmed
Oral
desloratadine 5 mg once daily for up to 4 weeks in
patients with
seasonal allergic rhinitis (
SAR ) significantly reduced nasal ( including
congestion ) and non - nasal symptoms and improved health - related quality of life compared with placebo . -
pubmed
Desloratadine 5 mg once daily for 6 weeks significantly improved
pruritus and reduced the number of
hives compared with placebo in
patients with
chronic idiopathic urticaria (
CIU ) . -
pubmed
Desloratadine was well tolerated in clinical trials and had an adverse event profile similar to that of placebo in
patients with
SAR ( with or without
asthma ) or
CIU . -
pubmed
In a case - vignette , the condition of an 82 - year - old
man with acute
gastrointestinal bleeding is described comprehensively in combination with 3 different levels of information about the patient wishes ( no information , DNR order , advance directive ) . -
pubmed
OBJECTIVE : To examine functional improvement patterns of
persons with
stroke ,
traumatic brain injury (
TBI ) , and
spinal cord injury (
SCI ) . -
pubmed
RESULTS : With the exception of cognitive functioning for persons with
SCI , LOS was related to initial functional status , with
patients with greater disability having longer LOS ( eg , initial motor status for persons with
stroke was 48.3 for those with a 2 - week stay , 36.8 for a 6 - week stay , with the averages between decreasing monotonically ) . -
pubmed
In 16
patients with
ARDS submitted to mechanical ventilation in volume - controlled mode with a supportive respiratory rate of 15 breaths / minute , we constructed the static PV curve on the first day of respiratory support and determined the intrinsic positive end - expiratory pressure ( PEEPi4 ) during a prolonged end - expiratory pause ( 4 seconds ) . -
pubmed
Between July 1994 and July 2001 , all
patients with
superficial transitional cell carcinoma (
TCC ) of urinary bladder ( pT1 and pTa ) , 7 days after undergoing transurethral resection of
tumor were subjected to intravesical instillation of 60 mg
BCG ( Danish 1331 ) combined with 5 million IU
interferon alpha-2b ( Intron - A ) mixed with 50 ml of physiological saline weekly for 8 weeks , then fortnightly for 8 weeks , then monthly for 8 weeks , followed by maintenance dose at the end of the 9th , 12th , 18th , 24th months . -
pubmed
At the end of the 1st year of follow - up 84 % of
patients had no
tumor recurrence which dropped to 36 % at the end of 5 - year follow - up , while no incidence of
disease progression at the end of the first year was recorded but was 20 % at the end of 5 years , thereby resulting in a
disease progression - free 5 - year interval in 80 % of our
patients . -
pubmed
The epidemiology of invasive
Streptococcus agalactiae (
GBS ) disease was evaluated in South African children . -
pubmed
Shunt infection may be the cause in
patients with ventriculoperitoneal shunt , who have
acute abdomen . -
pubmed
[ Causative factors in development of
breast carcinoma in
mice ] . -
pubmed
Rat behavior in two models of
anxiety and brain [
3H]
muscimol binding : pharmacological , correlation , and multifactor analysis . -
pubmed
The contribution of GABAergic mechanisms to
rat emotional behavior in two
animal models of
anxiety ( open field test of
neophobia and aversively conditioned freezing reaction ) , was confirmed by pharmacological analysis , using anxiolytic (
midazolam ) and anxiogenic (
picrotoxin ) compounds . -
pubmed
The metabolism of
phenylalanine and
tyrosine in mutant
strains of
Escherichia coli . -
pubmed
Case 1 was a 44 - year - old
man with T1N2M0
adenocarcinoma . -
pubmed
Case 2 was a 67 - year - old
man with T4N1M0
squamous cell carcinoma . -
pubmed
Case 3 was a 72 - year - old
man with T4N2M0
squamous cell carcinoma . -
pubmed
Patients with
vagal paragangliomas typically present with an asymptomatic neck mass and , less frequently , with
cranial neuropathies . -
pubmed
Stratified by treatment group , the 3 - year incidence of
CIN was 0/23 ( 0 % ) in
prednisone treated
patients , 0/4 ( 0 % ) in
AZA treated
patients , 2/8 ( 25 % ) in
IVCYC treated
patients , and 4/26 ( 15 % ) in
CYC +
AZA +
prednisone treated
patients . -
pubmed
Cardiovascular manifestations of
beriberi based on a study of ten
patients . -
pubmed
The discovery of
lithium 's efficacy as a mood - stabilizing agent revolutionized the treatment of
patients with
bipolar disorder and after 5 decades this drug continues to be the mainstay of treatment of this disorder . -
pubmed
Antidepressant effects of different schedules of repetitive transcranial magnetic stimulation vs.
clomipramine in
patients with
major depression : relationship to changes in cortical excitability . -
pubmed
The aim of the present study was to compare efficacy of rTMS in various configurations and
clomipramine treatment in
patients with
major depression (
MD ) and to evaluate the relationship between clinical outcome and changes in cortical excitability . -
pubmed
Fifty - nine
MD patients were randomized to receive ( 1 ) left ( n = 12 ) or right ( n = 12 ) 3 Hz rTMS with placebo medication ; ( 2 ) left ( n = 10 ) or right ( n = 9 ) 10 Hz rTMS with placebo medication ; ( 3 ) active medication (
clomipramine ) with sham rTMS ( n = 16 ) . -
pubmed
Our results suggest that 3 Hz left rTMS has a higher therapeutic efficacy and tolerability in
patients with
MD . -
pubmed
Subcortical white matter metabolic changes remote from focal
hemorrhagic lesions suggest diffuse
injury after
human traumatic brain injury . -
pubmed
METHODS : Sixteen normal
volunteers and 10
TBI patients ( Glasgow Coma Scale score , 4 - 10 ; age , 17 - 64 yr ; 6 with focal and 4 with diffuse
injury ) were studied . -
pubmed
Vulvar lipoleiomyoma in a
dog . -
pubmed
A
vulvar neoplasm from a 5 - year - old female
Siberian Husky dog was removed surgically and examined histologically . -
pubmed
This is , to the author 's knowledge , the first report of
canine vulvar lipoleiomyoma . -
pubmed
METHODS : The study involved 188
subjects , 101
hypertensives and 87 normotensives . -
pubmed
The diagnosis of two
patients with the infantile form of
GM1 gangliosidosis and 11 carriers in a small mountainous village in Cyprus prompted us to carry out a study in order to establish the frequency of carriers in the village and identify the mutations involved . -
pubmed
Non - REM - sleep instability in
recurrent sleepwalking in pre - pubertal
children . -
pubmed
BACKGROUND AND PURPOSE : We questioned whether or not the sleep of pre - pubertal
children with
recurrent sleepwalking was different from that recorded in normal
children . -
pubmed
However , the utility of PET / CT in
patients with both
cancer and
osteoporosis is less well delineated . -
pubmed
In this case , a
patient with known metastatic
colorectal cancer who was investigated by many forms of conventional imaging for back and
pelvic pain was found to have
osteoporotic fractures using PET / CT . -
pubmed
OBJECTIVE : To determine the complication and hospitalization rates in
children with
cystic fibrosis (
CF ) by mode of diagnosis . -
pubmed
Complications were defined for the calendar year of diagnosis as
stunting ( length & lt;3rd percentile ) ,
wasting ( weight & lt;3rd percentile ) , positive
Pseudomonas aeruginosa culture results , and
hypoelectrolytemia or
edema and
hypoproteinemia . -
pubmed
Subsequent molecular genetic studies revealed that a
hydatid cyst from the plateau pika ,
Ochotona curzoniae , had unique mitochondrial DNA sequences which are dissimilar to any published sequences of Echinococcus . -
pubmed
shiquicus has been found at other areas surveyed on the plateau ; however , no
infections in
humans caused by
E. - pubmed
( iv ) For
patients with non - thymomatous autoimmune
MG , thymectomy ( TE ) is recommended as an option to increase the probability of remission or improvement ( level B recommendation ) . -
pubmed
( ix ) All
neuromyotonia patients should be treated symptomatically with an anti -
epileptic drug that reduces
peripheral nerve hyperexcitability ( good practice point ) . -
pubmed
The effect of heat
shock on
paclitaxel production in
Taxus yunnanensis cell suspension cultures : role of
abscisic acid pretreatment . -
pubmed
The heat
shock ( HS ) response is a conserved cellular defense mechanism to elevated temperatures , observed in cells from bacteria to
human . -
pubmed
Seroprevalence of
herpes simplex virus types 1 and 2 ,
Epstein - Barr virus , and
cytomegalovirus in
children with
acute lymphoblastic leukemia in Egypt . -
pubmed
This study aimed at studying seroprevalence of 3 herpes viruses
Herpes simplex virus types 1 and 2 ( HSV 1 and 2 ) ,
Epstein - Barr virus (
EBV ) , and
cytomegalovirus (
CMV ) in children with
acute lymphoblastic leukemia (
ALL ) . -
pubmed
METHODS : We conducted this study on 68 newly diagnosed pediatric
patients with
ALL presented to the Pediatric Oncology Service of National Cancer Institute , Cairo University , Egypt from November 2001 to June 2003 . -
pubmed
CONCLUSION : The data show a higher exposure to
HSV-1 and 2 both primary
infections and reactivation among
ALL children . -
pubmed
Therefore ,
acyclovir prophylaxis could be highly effective for seropositive
leukemic patients who are undergoing induction chemotherapy . -
pubmed
Speech characteristics of
patients with
pallido - ponto - nigral degeneration and their application to presymptomatic detection in at - risk relatives . -
pubmed
PURPOSE : This report describes the speech characteristics of
individuals with a
neurodegenerative syndrome called
pallido - ponto - nigral degeneration (
PPND ) and examines the speech samples of at - risk , but asymptomatic , relatives for possible preclinical detection . -
pubmed
METHODS : Study population comprising 143
outpatients with clinical diagnosis of probable
AD ( 73.3 + /- 7.0 years ) were classified into 2 groups according to the presence or absence of
SBIs on magnetic resonance imaging . -
pubmed
RESULTS :
SBIs were noted in 32.9 % ( 47/143 ) of the
AD patients . -
pubmed
Amnionitis with
Ureaplasma urealyticum or other microbes leads to increased morbidity and prolonged hospitalization in very low
birth weight infants . -
pubmed
Children of mothers with positive amniotic fluid cultures had significantly lower gestational ages ( 26 + 4 weeks for
Ureaplasma urealyticum [ p=0.04 ] and 25 + 5 weeks for other microorganisms [ p=0.0017 ] versus 28 + 6 weeks for mothers with negative amniotic fluid cultures ) and lower
birth weights ( 975 g [ n.s . ] -
pubmed
In none of the patients treated with macrolids for proven
Ureaplasma urealyticum amnionitis could the microbes be eradicated . -
pubmed
Twenty
patients with moderate to severe
COPD [ 12
women , 66 + /- 9.4 years of age and forced expiratory volume in 1 second ( FEV(1 ) ) of 32 % + /- 12 % of predicted value ] and 20 healthy age- , gender- , and
body mass index ( BMI)-matched controls ( 10 nonsymptomatic smokers and 10 nonsmokers ) were included in the study . -
pubmed
In the present study ,
bipolar I patients were assessed at index hospitalization using standardized symptom measures and followed up to 28 months . -
pubmed
METHODS : This project was a prospective study of a convenience sample of 304 ED
patients undergoing ECG analysis during their evaluation in the ED of a level 1
trauma center . -
pubmed
During the past decade , the involvement of different cell types in
CHS has been investigated by the use of antibody - induced depletion of specific subtypes of immunological cells and by studying knockout
mice lacking one or more of these immunological cell populations . -
pubmed
OBJECTIVES : To develop a method for studying the collective cellular dynamics of immune cells in the draining lymph nodes during
CHS in intact
animals . -
pubmed
Evaluation of the available anti -
HCV antibody detection tests and RT - PCR assay in the diagnosis of
hepatitis C virus infection . -
pubmed
The study included 316 serum samples from three groups : blood donors , patients on maintenance hemodialysis ( HD ) and patients infected with the
human immunodeficiency virus (
HIV ) . -
pubmed
For patients on
HD and those positive for
HIV , the test positivity was respectively 59.3 % and 5.3 % by ELISA , 64 % and 10.5 % by RIBA and , 66.3 % and 21 % by PCR test . -
pubmed
The percentage of false negativity of
HCV - Ab by ELISA and RIBA when compared with RT - PCR test was 3.5 and 8.1 % for samples blood donors , 17.1 and 25.7 % for
HD patients and 5.6 and 16.7 % for
HIV - infected samples , respectively . -
pubmed
The false positivity of
HCV - Ab by ELISA and RIBA , when compared with RT - PCR , was 5 % , 3.9 % and zero for blood donors ,
HD patients and
HIV - HCV co - infected cases , respectively . -
pubmed
Thus , it is very important to screen blood donors ,
HD patients and
HIV - infected patients by using the RT - PCR for
HCV - RNA to avoid false negative results . -
pubmed
[ A case of complete remission(CR)persisting from UFT - E in an old
patient with liver
metastasis of
gastric cancer ] . -
pubmed
A 82 - year - old
woman with
gastric cancer underwent distal gastrectomy with level 2 lymph node dissection(M , Less , 2.2 x 2.0 cm , type 1 , fH0 , fP0 , fM0 , fT2 , fN2(+ ) , por 1 , med , INF beta , ly2 , v2 , fPM(- ) , fDM(- ) , fStage IIIa ) . -
pubmed
Locomotor activity is a predictive test after global
ischemia - reperfusion in
Mongolian gerbils . -
pubmed
OBJECTIVE : The
Mongolian gerbil is one of the main
animal species used for the study of global
ischemia , due to its specific Circle of Willis . -
pubmed
The locomotor activity of the
animals was also examined in an open field at 24 hours and seven days after
ischemia . -
pubmed
CONCLUSIONS : Locomotor activity in an open field is a useful reference as a predictive test to determine the sensitivity of experimental
animals to
ischemia . -
pubmed
One
patient had a combination of acquired
coarctation and false
aneurysm . -
pubmed
CONCLUSION : Covered stent implantation for treatment of
aortic coarctation is safe and highly effective in selected
patients . -
pubmed
infestation and suspected
demodicosis of
alpacas (
Vicugna pacos ) in New Zealand . -
pubmed
Rate of
weight loss and mortality , of the
Nigerian periwinkle ,
Tympanotonus fuscatus var . - pubmed
EXPERIMENTAL APPROACH :
O ( 2 )(- ) was generated in primary cultures of
angiotensin II - stimulated preglomerular vascular smooth muscle cells from spontaneously
hypertensive rats and detected by
lucigenin - enhanced chemiluminescence . -
pubmed
A 66 - year - old
man developed
tension pneumocephalus after failed lumbar drainage before clipping surgery for a ruptured
anterior communicating artery aneurysm . -
pubmed
The
patient 's neurological status deteriorated suddenly into
coma within 15 hours after uneventful clipping of the
aneurysm . -
pubmed
Urinary
6 - sulfatoxymelatonin level in age - related
macular degeneration patients . -
pubmed
The purpose of this study was to investigate
melatonin levels in age - related
macular degeneration (
AMD )
patients by measurement of
6 - sulfatoxymelatonin levels ( aMT6s ) , the major metabolite of
melatonin in urine , and compare it with a group of age- and gender - matched controls . -
pubmed
METHODS : The first urine of the morning was collected from 43
AMD patients and 12
controls who did not have
AMD . -
pubmed
After adjustment for various factors ( age , smoking ,
cancer , and
coronary heart disease ) that may influence the aMT6s level , the odds - ratio of urinary aMT6s comparing
AMD patients to controls was 0.65 ( 95 % confidence interval=0.48 - 0.88 , p=0.0036 ) , indicating that urinary aMT6s level in
AMD patients was lower than in controls even after multivariate adjustment . -
pubmed
CONCLUSIONS : Urinary aMT6s level in
AMD patients was 40 % lower than in age- and gender - matched controls . -
pubmed
This difference between
AMD patients and controls is present after adjustment for the factors of age , smoking , and histories of
cancer and
coronary heart disease . -
pubmed
Excessive thyroid hormone induces
cardiac hypertrophy and promotes
heart failure in
patients with
hyperthyroidism , but the mechanism remains elusive . -
pubmed
Rats were orally administered with
levothyroxine ( 100 microg / kg , T(4 ) ) for 4 weeks to induce
hyperthyroidism . -
pubmed
The calculated
stroke volume decreased and the shortening amplitude - frequency relationship in unloaded contraction of isolated cardiomyocytes was negative in T(4)-treated
rats . -
pubmed
RECENT FINDINGS : The development of molecular diagnostics has markedly improved the ability to rapidly identify
infections in transplantation
patients and has improved clinical care . -
pubmed
Monitoring for
cytomegalovirus and
Epstein - Barr virus by PCR offers the opportunity for preemptive interventions . -
pubmed
Concomitant administration of
nitric oxide and glucocorticoids improves protection against bronchoconstriction in a
murine model of
asthma . -
pubmed
The
cytotoxicity data suggest that these compounds may be endowed with important antitumor properties , especially H(3)L(1 ) and
[ Pt ( mu - H ( 3 ) L ( 2 ))]( 2 ) since they not only circumvent
cisplatin resistance in
A2780cisR cells but also exhibit high antiproliferative activity in
human non -
small cell lung cancer NCI - H460 cells . -
pubmed
Mice received diets enriched in
methionine with low or high levels of
folate ,
B ( 12 ) and B ( 6 ) ( diets B and C , respectively ) , and diet only with low levels of
folate ,
B ( 12 ) and B ( 6 ) ( diets D ) , to induce mild
HHcy . -
pubmed
Normal
mice fed on diets B , C and D presented mild
HHcy , but they did not develop
atherosclerotic lesions after 24 weeks of diet . -
pubmed
Awareness and filling - in of the
human blind
spot : linking psychophysics with retinal topography . -
pubmed
Owing to meiotic irregularities of
triticale hybrids ,
aneuploidy may affect the efficiency of androgenesis more severely than in meiotically stable crops . -
pubmed
This study addresses the issue of
aneuploidy among androgenic regenerants of
triticale . -
pubmed
Rye chromosomes involved in
aneuploidy greatly outnumbered
wheat chromosomes ; in C(0 )
rye chromosomes 2R and 5R were most frequently involved . -
pubmed
[ Protective effect of limb ischemic preconditioning against
liver ischemia /
reperfusion injury in the
rat ] . -
pubmed
OBJECTIVE : To study the protective effect of limb ischemic preconditioning against
liver ischemia /
reperfusion injury in the
rat . -
pubmed
METHODS :
Rats were randomly divided into four groups ( n = 8) : ( 1 ) Sham group ( S group ) ,
rats without ischemic preconditioning ( IPC ) , ( 2 )
Ischemia / reperfusion ( I / R ) without IP ( I / R group ) ; ( 3 )
Rats with 5 min IPC ( IPC group ) ; ( 4 )
Rats with lower limbs IPC and repeated three times ( remote
ischemic preconditioning , RPC group ) ; The
rats were subjected to 60 - min sustained
liver ischemia followed by 180 - min reperfusion except S group . -
pubmed
All
ischemia rats were only subjected to 70 %
liver ischemia . -
pubmed
CONCLUSION : The limb ischemic preconditioning has a protective effects against
liver ischemia /
reperfusion injury in the
rat , possibly are due to suppression of liver inflammatory reaction , improvement of liver microcirculation . -
pubmed
Pressure
ulcers are one of the most common complications in elderly , incontinent or paralyzed
patients . -
pubmed
Lipopolysaccharide ( LPS ) ,
d - galactosamine (
GalN)-induced
FHF is a well - established model of
liver injury in
mice . -
pubmed
RESULTS : After the induction of
FHF , all control
mice died within 12 hr of
GalN / LPS administration . -
pubmed
Palliative care for
patients with
Huntington ' s disease # 201 . -
pubmed
The subarachnoid infusion of narcotics by programmable devices in
patients with chronic non - malignant
pain can be a useful therapeutic method . -
pubmed
We present a case report of a
woman with both chronic
perineal pain and sciatic
pain with radiation to her lower limbs caused by
failed back surgery syndrome . -
pubmed
After surgical implantation of a programmable infusion pump , the
patient 's
leg pain improved with an intrathecal infusion of
morphine and
bupivacaine . -
pubmed
In all
patients , laparoscopy was considered to be contraindicated due to extensive
pelvic adhesions . -
pubmed
After 45 embryo transfer procedures in 19
patients , 18 pregnancies with 12 live births , 6
miscarriages and 1 immature delivery ( probably related to
cervical insufficiency leading to
chorioamnionitis and subsequent
rupture of the membranes ) were observed . -
pubmed
CONCLUSION(S ): Essure ( ) devices are effective in inducing proximal
tubal occlusion in subfertile
patients with
hydrosalpinges . -
pubmed
OBJECTIVE : To evaluate the efficacy of endometrial biopsy followed by intrauterine system - releasing
levonorgestrel (
LNG -
IUS ) insertion in the treatment of
women with
menorrhagia . -
pubmed
Ninety - two
patients who had
menorrhagia due to non - malignant causes were sequentially recruited into the study over a 3 - year period ( age range 29 - 51 years ) . -
pubmed
Because airway management is often complicated in
trauma patients , alternative devices need to be available preclinical and a fiber - optic endoscope should be available within the hospital . -
pubmed
Recently , an
animal model of combined
fatigue was designed by housing
rats in a cage filled with water . -
pubmed
Rats were housed for 5 d under water - immersed conditions , and the extent of
fatigue was evaluated by a weight - loaded forced swimming test . -
pubmed
The past decade of investigation into the pharmacologic treatment of
hypertension in
children has been rewarding . -
pubmed
The studies have shown that blood pressure medications effectively reduce blood pressure in
children with
hypertension and that these agents are generally well tolerated with few treatment - related adverse effects . -
pubmed
RESULT : Medicinal
tween 80 and injectable
tween 80 with 5 % concentration caused obvious vascular hyper permeability in
ICR mice , but the degree of
vascular hyperpermeability caused by injectable
tween 80 was lighter than by medicinal
tween 80 . -
pubmed
Streptococcus pneumoniae is an aerotolerant gram - positive bacterium that causes an array of diseases , including
pneumonia ,
otitis media , and
meningitis . -
pubmed
Eleven
patients with
idiopathic Parkinson ' s disease consented to participate in neuronal recordings during stimulator implantation surgery . -
pubmed
Sleep apnoea and the potential benefits of a good night 's sleep in
patients receiving maintenance dialysis . -
pubmed
The study population consisted of 116
patients with
PCAD , and 119 controls . -
pubmed
OBJECTIVE : To determine the clinical effect , treatment times , and rheoencephalogram changes in
vertebral artery type cervical spondylosis patients treated with innovative Tuina manipulations . -
pubmed
METHODS : One hundred and twenty six
cervical spondylosis patients ( vertebral artery type ) were randomly divided into test and control groups . -
pubmed
CONCLUSION : Both innovative Tuina manipulations and routine Tuina manipulations produced satisfactory therapeutic results in
vertebral artery type cervical spondylosis patients . -
pubmed
Biweekly
Docetaxel and
S-1 combination chemotherapy as first - line treatment for elderly
patients with advanced
gastric cancer . -
pubmed
BACKGROUND : This study evaluated the clinicopathological features and survival rates of
patients with
inflammatory bowel disease who developed
colorectal cancer (
CRC ) . -
pubmed
We agree with the approach to management of
RCDI that has been proposed in several articles , that is , on confirmation of a first
recurrence of
CDI by a stool toxin assay and clinical symptoms , a 14 - day course of
metronidazole or
vancomycin ; for a second
recurrence , a tapered - pulsed course of
vancomycin ; and , for 3 or more
recurrences , a repeat course of the tapered - pulsed
vancomycin and adjunctive
Saccharomyces boulardii or
cholestyramine . -
pubmed
Hypothesis - based weight - of - evidence evaluation of the
human carcinogenicity of
toluene diisocyanate . -
pubmed
It is classified as a possible
human carcinogen , based primarily on increased
tumor incidences in
rodents treated with
TDI by oral gavage . -
pubmed
The experimental animal studies indicate that inhalation exposure to
TDI does not induce
tumors in
rats or
mice . -
pubmed
Tumors observed after oral gavage exposure are most likely due to the conversion of approximately 5 % of the administered
TDI to
toluene diamine (
TDA ) , a known
rodent tumorigen . -
pubmed
This contention is supported by the observations that
TDA is rapidly formed from
TDI during in vitro
genotoxicity assays , the spectra of responses to
TDA and
TDI in these assays and in oral bioassays are essentially the same , and
TDI is not genotoxic in
rodents or
humans in vivo after inhalation exposure , when
TDA is not formed to a biologically significant degree . -
pubmed
The primary objective of this 96 - week open - label , noncomparative , multicenter Phase 3b study ( NCT00478231 ) was to assess the safety of
maraviroc in combination with optimized background therapy ( OBT ) , which could include recently introduced agents such as
darunavir and
raltegravir in
TE patients in Brazil with R5
HIV-1 and limited therapeutic options . -
pubmed
Lung volume recruitment involves deep inflation techniques to achieve maximum insufflation capacity in
patients with
respiratory muscle weakness , in order to increase peak
cough flow , thus helping to maintain airway patency and improve ventilation . -
pubmed
METHODS : Thirty eight ( 38 )
FXTAS patients and 10 age - matched normal controls underwent a detailed neurological examination that included all but one item ( i.e. -
pubmed
RESULTS : The
FXTAS patient group displayed substantially higher prevalence of
parkinsonian features including body
bradykinesia ( 57 % ) and
rest tremor ( 26 % ) , compared to the control group . -
pubmed
Furthermore ,
parkinsonism was identified in 29 % of
FXTAS patients . -
pubmed
METHODS : A sample of
subjects with a
parkinsonian disorder was evaluated . -
pubmed
RESULTS : A total of 32
subjects with atypical
parkinsonism and 54 subjects with
Parkinson ' s disease were included . -
pubmed
METHODS : We conducted a prospective study of 120 consecutive
patients admitted for
acute myocardial infarction , from April 2011 to March 2012 . -
pubmed
All
patients have undergone an overnight sleep study using a portable diagnostic device , in the 15 days following the
acute coronary syndrome . -
pubmed
Smoking was the major cardiovascular risk factor with 72 % of all
patients ; prevalence of
diabetes was 40 % and
hypertension was found in 44 % of the population . -
pubmed
Severe
OSA was diagnosed in 16 % of all
patients and mean AHI was 15.76 + - 14.93 . -
pubmed
Mean ESS was 2.2 + - 1.84 in the global population while it was 5.2 + - 1.2 in
patients with severe
OSAS . -
pubmed
CONCLUSION : The prevalence of
OSA in
patients with
acute myocardial infarction was very high . -
pubmed
BACKGROUND : Despite the fact that the number of disabled
individuals participating in sports is increasing , there are only sparse reports in the literature concerning
overuse injuries . -
pubmed
Data were collected using semi - structured pretested Amharic version questionnaire by interviewing index children 's mothers / caretakers , copying from vaccine card and observing
BCG vaccine
scar . -
pubmed
We found that the proportion of MAIT cell in blood and colon of
HIV+ patients are reduced in untreated
infection . -
pubmed
Infection of the optic apparatus and hypothalamus by
Mycobacterium haemophilum . -
pubmed
Impaired leptomeningeal collateral flow contributes to the poor outcome following experimental
stroke in the
Type 2 diabetic mice . -
pubmed
Using Doppler optical coherent tomography , a robust recruitment of leptomeningeal collateral flow was detected immediately after
middle cerebral artery ( MCA ) occlusion in C57BL/6
mice , and it continued to grow over the course of 1 week . -
pubmed
In contrast , an impairment of collateral recruitment was evident in the Type 2 diabetic db / db
mice , which coincided with a worse
stroke outcome compared with their normoglycemic counterpart db/+ , despite their equally well - collateralized leptomeningeal anastomoses . -
pubmed
Similar to the wild - type
mice , both db/+ and db / db
mice underwent collateral growth 7 d after MCA
stroke , although db / db
mice still exhibited significantly reduced retrograde flow into the MCA territory chronically . -
pubmed
Acutely induced
hyperglycemia in the db/+
mice did not impair collateral flow after
stroke , suggesting that the state of
hyperglycemia alone was not sufficient to impact collateral flow . -
pubmed
Our results suggest that the impaired collateral status contributes to the exacerbated
ischemic injury in
mice with
Type 2 diabetes , and modulation of collateral flow has beneficial effects on
stroke outcome among these subjects . -
pubmed
Several prognostic factors can predict
disease progression and therapeutic outcomes in those
patients . -
pubmed
Positive voided urine cytology predicts worse pathological findings of nephroureterectomy specimens in
patients with
upper tract urothelial carcinoma : does selective ureteral cytology have an additional efficacy ? -
pubmed
OBJECTIVE : After radical nephroureterectomy , substantial numbers of
patients with
upper tract urothelial carcinoma are ineligible for adjuvant chemotherapy owing to
diminished renal function . -
pubmed
Herein , we evaluated pre - operative voided urine cytology and the additional efficacy of selective ureteral cytology for predicting pathological features in
upper tract urothelial carcinoma patients . -
pubmed
METHODS : This retrospective cohort study comprised 722
patients with
upper tract urothelial carcinoma who underwent radical nephroureterectomy . -
pubmed
Patients with concomitant
bladder cancer and those who received neoadjuvant therapy were excluded . -
pubmed
Evaluating the Role of
Corticosteroid Pulse Therapy in
Patients With
Secondary Progressive Multiple Sclerosis Receiving
Mitoxantrone : A Double Blind Randomized Controlled Clinical Trial . -
pubmed
OBJECTIVES : To evaluate the role of
corticosteroid pulse therapy in
patients with
SPMS receiving
mitoxantrone . -
pubmed
PATIENTS AND METHODS : A double blind randomized controlled clinical trial was performed on 71
patients with
SPMS referred to Shahid Sadoughi Hospital ( Yazd , Iran ) for receiving
mitoxantrone in two groups . -
pubmed
Many
patients with
Parkinson ' s disease (
PD ) will develop
cognitive impairment . -
pubmed
Effect of pregnancy on the activity and infectivity of
hepatitis B virus in women with
chronic hepatitis B infection . -
pubmed
RESULTS : From the result obtained , significance variance ( p<0.05 ) existed between
HIV positive persons and persons who tested positive to
HIV /
HBV /
HCV triple infection before and after the commencement of HAART . -
pubmed
Cognitive deficits in
patients with
obsessive - compulsive disorder - electroencephalography correlates . -
pubmed
The aim of our study was to examine the association between
cognitive impairment and current source density markers in
patients with
OCD . -
pubmed
METHODS : Resting - state eyes - closed electroencephalography ( EEG ) data were recorded in 20
patients with
OCD and 15 healthy controls who were involved in the study . -
pubmed
RESULTS : Frontal delta and theta EEG sources showed significantly higher activity in the whole group of
patients with
OCD ( N=20 ) than in control subjects ( N=15 ) . -
pubmed
Subsequent analysis revealed that this excess of low - frequency activity was present only in the subgroup of eleven
patients with
cognitive impairment ( based on the performance in the Trail - Making Test - A ) . -
pubmed
CONCLUSION : The present results suggest that frontal low - frequency cortical sources of resting - state EEG rhythms can distinguish groups of cognitively impaired and cognitively intact
patients with
OCD . -
pubmed
Based on our results , future studies should consider whether the present methodological approach provides clinically useful information for the revelation of
cognitive impairment in
patients with
OCD . -
pubmed
Despite improved perioperative care , the increasing complexity and extensiveness of surgical interventions , in combination with an expanding number of resections in
patients with
compromised liver function , still results in an incidence of
postresectional liver failure (
PLF ) of 1 - 9 % . -
pubmed
Some of the respondents had ever tested for
HIV and few had ever been treated for
STI more than once . -
pubmed
The goal of this study was to explore the prognostic value of these parameters in
idiopathic pulmonary arterial hypertension (
IPAH )
patients . -
pubmed
Study on AAV - mediated gene therapy for
diabetes in humanized liver
mouse to predict efficacy in
humans . -
pubmed
As the results , AAV2 - PG succeeded to improve the
hyperglycemia of
STZ - induced
diabetic humanized liver
mice . -
pubmed
In PARADIGM -
HF ,
patients with
HFrEF treated with
sacubitril /
valsartan had 20 % less risk for
cardiovascular death or hospitalization for
heart failure ( the primary endpoint ) , 20 % less risk for
cardiovascular death , 21 % less risk for first hospitalization for
heart failure , and 16 % less risk for
death from any cause , compared with
enalapril ( all p & lt ; 0.001 ) . -
pubmed
Concerning tolerability , the
sacubitril /
valsartan group had higher proportions of
patients with
hypotension and nonserious
angioedema but lower proportions with
renal impairment ,
hyperkalemia , and
cough , compared with the
enalapril group . -
pubmed
Cryopreserved
porcine hepatocytes isolated from the same
strain were suspended in physiological saline and transfused through the catheter . -
pubmed
We hypothesized that
ADPKD patients have a more severely impaired urine concentrating capacity in comparison to other
patients with
chronic kidney disease at a similar level of kidney function , with consequently an enhanced
AVP response to water deprivation with higher circulating
AVP concentrations . -
pubmed
METHODS : 15
ADPKD ( eGFR<60 )
patients and 15 age- , sex- and
eGFR - matched controls with
IgA nephropathy (
IgAN ) , underwent a water deprivation test to determine maximal urine concentrating capacity . -
pubmed
In
ADPKD patients , height adjusted total kidney volume ( hTKV ) was measured by MRI . -
pubmed
METHODS : Sixty - three
patients with
aSAH between January 2012 and October 2014 , who developed
DCI ( defined as new focal deficit or decline in Glasgow Coma Score ) and in which PE ( n = 45 ) or NE ( n = 18 ) treatment was initiated were evaluated in this retrospective study . -
pubmed
CONCLUSIONS : Our study suggests that
patients with
DCI after
aSAH initiated on
PE are more likely to require treatment change to another vasopressor and are at greater risk for poor clinical outcomes compared to
patients started on NE . -
pubmed
METHODS : In a case control study , 118 clinically diagnosed
Type 2 Diabetes Mellitus (
T2DM )
patients attending Diabetic Clinic at the Nkawie Government Hospital were enrolled between October and December 2015 . -
pubmed
When a
patient presents with an initial episode of
ON ,
patients should undergo further tests . -
pubmed
A Select Subset of Electron Transport Chain Genes Associated with
Optic Atrophy Link Mitochondria to Axon Regeneration in
Caenorhabditis elegans . -
pubmed
Using mechanosensory neurons of the nematode
Caenorhabditis elegans to test regeneration after
neuronal injury in vivo , we surveyed genes related to mitochondrial function for effects on axon regrowth after laser axotomy . -
pubmed
Avian leukosis virus (
ALV ) is an avian oncogenic retrovirus that can induce virus - associated
neoplasia and causes great economic loss in poultry industry . -
pubmed
Our objective was to demonstrate the diversity of circulating extracellular RNA ( ex - RNA ) release during acute exercise in
humans and its relevance to exercise - mediated benefits on
vascular inflammation . -
pubmed
[
Hyperuricemia in
obese patients with pharmacologically treated essential
hypertension ] . -
pubmed
Thus far , there is no consensus on the treatment of
patients with asymptomatic
hyperuricemia , despite a large number of studies conducted worldwide . -
pubmed
MATERIAL AND METHODS : A total of 109 obese
patients ( mean BMI=34.6 + -3.5 kg / m2 ) were included in this study , selected from the outpatients at the Clinic of Arterial
Hypertension , the unit of the Cardinal Stefan Wyszynski Institute of Cardiology in Warsaw . -
pubmed
CONCLUSION : The incidence of
hyperuricemia demonstrated in this study confirms the findings of other authors and indicates a fairly common prevalence of this phenomenon among a population of
patients with
hypertension . -
pubmed
OBJECTIVE :
Progesterone supplementation prevents
preterm birth (
PTB ) in some high - risk
women , but its mechanism of action is unknown . -
pubmed
METHODS :
Human fetal membranes were collected at elective cesarean at term ( no labor , no
infection ; n = 6 ) , washed , and pretreated with / without
progesterone ( 125 ng / mL ) for 24 hours . -
pubmed
We also discuss the potential clinical utilization of this lncRNA as a diagnostic and prognostic biomarker for
cancer patients . -
pubmed
Successful Treatment of
Osteosarcoma Without
Methotrexate in a 13 - Year - Old
Boy With
Down Syndrome . -
pubmed
Osteosarcoma is the most common primary
bone tumor in
children , and only 1 article in the literature describes a case of
osteosarcoma in a
patient with
Down syndrome . -
pubmed
Although
osteosarcoma is generally treated with chemotherapy regimens that include high - dose
methotrexate ,
patients with
Down syndrome have heightened sensitivity to the
toxicities of
methotrexate . -
pubmed
This case report describes the successful treatment of
osteosarcoma in a pediatric
patient with
Down syndrome without
methotrexate . -
pubmed
Schisandra chinensis Fructus and Its Active Ingredients as Promising Resources for the Treatment of
Neurological Diseases . -
pubmed
Here , we set out to characterize the dynamics of macrophage infiltration and their functional contribution to muscle regeneration by comparing young and aged
animals upon
acute sterile injury . -
pubmed
METHODS : A total of 159
patients who had primary
osteoarthritis of the knee with
varus deformity underwent TKA . -
pubmed
METHODS : A retrospective multicentric study analyzed the outcome of
patients admitted to the ICU with a newly diagnosed
lung cancer ( diagnosis within the month ) between 2010 and 2013 . -
pubmed
RESULTS : Out of the 100
patients , 30 had
small cell lung cancer (
SCLC ) and 70 had
non - small cell lung cancer . -
pubmed
CONCLUSION : This study shows that ICU management can be appropriate for selected newly diagnosed
patients with advanced
lung cancer , and chemotherapy might improve outcome for
patients with
SCLC admitted for
cancer - related complications . -
pubmed
WHAT IS KNOWN ALREADY : ICSI is a successful treatment for
infertility , but not in all
individuals . -
pubmed
Conclusion Standard treatment combined LRCD showed better comprehensive effect for
dry eyes and
dry mouth in
pSS patients with FDDOS , and was more safe . -
pubmed
The possible sources of
iodine in milk are supplemental
iodine in dairy feeds ,
iodophor - containing sanitizers used at the dairy farm and/or the processing plant ,
iodophor - containing teat dips used to control the spread of
mastitis among dairy
cows , and
iodine - containing medications used by veterinarians . -
pubmed
The caged Dex- p - siRNA nanoparticles targeting GFP successfully photoregulated GFP expression in
tumor - bearing
mice via intratumoral injection . -
pubmed
Incidence of and risk factors for
cardiotoxicity after
fluorouracil - based chemotherapy in locally advanced or metastatic
gastric cancer patients . -
pubmed
OBJECTIVES :
Cardiotoxicity is an important side effect in
patients receiving chemotherapy and the application of
anthracycline drugs for
gastric cancer treatment is uncommon . -
pubmed
The purpose of this study was to determine the incidence rate of and risk factors for
cardiotoxicity in
gastric cancer patients treated with
fluorouracil - based chemotherapy . -
pubmed
MATERIALS AND METHODS : We retrospectively enrolled
patients with locally advanced or metastatic
gastric cancer from 2011 to 2016 . -
pubmed
The incidence of
cardiotoxicity and
patients ' clinical data were obtained from hospital clinical databases and manually reviewed . -
pubmed
Cardiotoxicity was observed in 38 of 129
patients ( 29.5 % ) . -
pubmed
Twelve
patients ( 9.3 % ) exhibited
toxicity greater than grade 2 , and 2 ( 1.6 % )
patients died of
cardiac toxicity . -
pubmed
CONCLUSIONS : Chemotherapy - related
cardiotoxicity may be underestimated in Chinese
gastric cancer patients . -
pubmed
Close monitoring for
cardiotoxicity and enhanced cardiac management are recommended for
patients who receive
fluorouracil - based chemotherapy , especially for
patients with high - risk factors for serious
cardiotoxicity . -
pubmed
In the current study , the effects of starch , as the main component in WGF , and beta - glucan in a whole - grain - like structural form ( WGLSF ) on hepatic IR and
glucose homeostasis were investigated using high - fat ( HF)-induced
obese C57BL/6J
mice . -
pubmed
After treatment for 8 weeks , the body
weight gain and IR of the
mice were significantly reduced . -
pubmed
Alcohol Binge Drinking and
Anxiety - Like Behavior in Socialized Versus Isolated C57BL/6J
Mice . -
pubmed
Using DID methodology ,
alcohol - preferring
strains of
mice such as C57BL/6J ( B6 )
mice consume enough
EtOH to achieve blood concentrations ( > = 1.0 mg / ml ) associated with
behavioral intoxication ( i.e. -
pubmed
METHODS : Male and female B6
mice were isolated or pair - housed for a period of 6 weeks prior to evaluation of
anxiety - like ( elevated plus maze , light and dark box , open field ) and drinking ( water , 10 %
sucrose , 10 to 30 %
EtOH ) behavior . -
pubmed
RESULTS : Increased
anxiety - like behavior and reduced
sucrose consumption were found in isolated
mice . -
pubmed
An understanding of the genetic network underlying the development and maintenance of this highly specialized region is instrumental to address issues about
human macula - related
retinopathies . -
pubmed
METHODS : A retrospective chart review was performed , identifying all
patients treated at our institution from July 2014 - June 2018 with the ICD-10 code N42.89 for
prostatic urethral stenosis . -
pubmed
RESULTS : Twenty - two
patients were identified with the diagnosis of
prostatic urethral stenosis . -
pubmed
Endoscopic management can be successful in stabilizing
patients , while urethroplasty can be feasibly performed in
patients with short
prostatic apical strictures . -
pubmed
We have reported accelerated
wound healing induced by intracellular
ATP delivery in
rabbits , through early massive accumulation , in situ proliferation , and M2 polarization of macrophages . -
pubmed
The presented case concerns a 32 - year - old
man with clinical diagnosis of
ARSACS . -
pubmed
BACKGROUND : Quality of hands - only cardiopulmonary resuscitation ( CPR ) is an important determinant of resuscitation outcome for
cardiac arrest patients cared for by lay rescuers . -
pubmed
We determined the changes in contractile reactivity induced by
ATP ,
uridine triphosphate (
UTP ) ,
uridine diphosphate (
UDP ) , and
Up4A in the femoral arteries of Otsuka Long - Evans Tokushima Fatty ( OLETF )
rats ( aged male type 2
diabetic rats ) and , Long - Evans Tokushima Otsuka ( LETO )
rats ( controls for OLETF
rats ) . -
pubmed
Label - Free Follow - Up Surveying of Post - Treatment Efficacy and Recurrence in Nasopharyngeal
Carcinoma Patients with Fiberoptic Raman Endoscopy . -
pubmed
Recurrent
nasopharyngeal carcinoma (
NPC ) is the main cause of poor prognosis for
NPC patients after chemo- and radiotherapies . -
pubmed
Amitraz induced
cytotoxic effect on
bovine cumulus cells and impaired oocyte maturation . -
pubmed
The aim of this study was to evaluate the genotoxic and
cytotoxic effects of
amitraz (
AMZ ) on the primary culture of
bovine cumulus cells ( CC ) and oocyte nuclear maturation . -
pubmed
This study contributes to a better understanding of
AMZ in this model , suggesting its potential
cytotoxicity and impact on
bovine reproduction . -
pubmed
Treatment with Ramucirumab -
paclitaxel in a metastatic
gastric cancer patient undergoing hemodialysis : A case report . -
pubmed
However , the combination chemotherapy of
ramucirumab and cytotoxic drug for hemodialysis (
HD )
patients has not been reported . -
pubmed
DIAGNOSIS : The
patient was diagnosed with advanced
gastric cancer at stage IIIb ( pT3N2M0 ) 11 months ago . -
pubmed
LESSONS : The
paclitaxel chemotherapy with
ramucirumab is effective and safe in
HD patients with metastatic
gastric cancer . -
pubmed
Dahl selectively bred
rats for susceptibility ( S
strain ) or resistance ( R
strain ) to the
hypertensive effect of high salt (
NaCl ) diet . -
pubmed
Hypertension was found in 18 % of 65
patients with untreated
gout , a lower prevalence than that previously reported . -
pubmed
The clinical characteristics and renal function of these
patients were compared with those of age matched groups of both normotensive
gouty subjects and normouricaemic patients . -
pubmed
The
hypertensive patients had significantly greater
body weights than their controls and also had a lower
glomerular filtration rate . -
pubmed
In preliminary testing , each of the target compounds displayed marginal activity against
L1210 leukemia in
mice . -
pubmed
[ Delayed
hypersensitivity in
patients with
chronic pancreatitis ] . -
pubmed
A
patient is described in whom breakthrough of
pain occurred from
uterine rupture during effective extradural analgesia , demonstrating the hypothesis of the " extradural sieve " . -
pubmed
Subsequent abolition of this
pain by addition of
fentanyl to
bupivacaine 0.25 % raises the question whether or not this combination should be avoided in
women with a scarred uterus undergoing " trial of labour " . -
pubmed
MRI in the presurgical evaluation of
patients with
frontal lobe epilepsy and
children with
temporal lobe epilepsy : pathologic correlation and prognostic importance . -
pubmed
We performed magnetic resonance imaging ( MRI ) using a high - field strength magnet ( 1.5 T ) in two series of 53
patients with intractable partial
epilepsy of frontal lobe or temporal lobe origin who subsequently received ablative surgery for their
seizure disorder . -
pubmed
Twenty - five percent of the
patients with negative MRI studies and 67 % of
patients with neuroimaging abnormalities restricted to the frontal lobe , were
seizure - free at a minimum duration of follow - up of 1 year . -
pubmed
None of the
patients with a multilobar MRI - detected abnormality was
seizure - free postoperatively . -
pubmed
In the second study the sensitivity and specificity of MRI - based hippocampal volumetry was determined in pediatric
patients with partial
epilepsy of temporal lobe origin unrelated to foreign - tissue pathology . -
pubmed
Hippocampal formation
atrophy in the
epileptic temporal lobe was identified in 63 % of
patients . -
pubmed
The sensitivity and specificity of hippocampal volumetry was 100 % in
patients with
mesial temporal sclerosis . -
pubmed
At the ultrastructural level , signs of low secretory activity were observed in
adenomas from
patients No . -
pubmed
Perifused
adenoma cells of
patients No . -
pubmed
1 , 2 and 3 compared with the
adenomas from
patients No . -
pubmed
However , the signal was more intense in the
adenomas from
patients No . -
pubmed
Failure of
lidocaine to suppress lethal ischemic
ventricular arrhythmias in a
canine model of previous
myocardial infarction . -
pubmed
lidocaine infusions were assessed in conscious
dogs with spontaneous
ventricular ectopy subacutely ( 48 h ) after anterior
myocardial infarction and in anesthetized
dogs with
ventricular tachyarrhythmias inducible by programmed ventricular stimulation at 4 - 11 days after anterior
myocardial infarction . -
pubmed
In conscious
dogs administered cumulative doses of
lidocaine at 48 h after
myocardial infarction , a significant reduction in the frequency of spontaneous ventricular ectopic complexes ( from 61 + /- 12 to 11 + /- 9 % of total complexes ) occurred only after administration of 10 mg / kg i.v . -
pubmed
In anesthetized postinfarction
dogs responding to baseline programmed stimulation with
ventricular tachyarrhythmias ,
lidocaine administration ( 6 mg / kg i.v . -
pubmed
in 5 of 10 postinfarction
animals tested , with an additional 3
animals displaying favorable stabilizations of induced
arrhythmias.(ABSTRACT TRUNCATED AT 250 WORDS ) -
pubmed
Anterior spinal artery syndrome after epidural anesthesia in a pregnant
diabetic patient with
scleredema . -
pubmed
Animal experiment showed that Wei Yang An inhibited the
ulcers . -
pubmed
Radiotherapy as salvage treatment in
patients with
Hodgkin ' s disease or
non - Hodgkin ' s lymphoma relapsing after initial chemotherapy . -
pubmed
[
Disorders of the pyelo - ureteral junction in children apropos of 89 cases in 74
patients ] . -
pubmed
Endoscopic or fluoroscopic pyeloureterotomy was performed in a total of 32
patients ( 34 ureters ) with
ureteropelvic junction obstruction (
UPJO ) or
ureteral stricture from March 1985 . -
pubmed
Sixty - seven ( 39 % )
patients had
ventricular arrhythmias ( PCC -
VT -
VF ) , of whom 17 ( 9.8 % ) had
VT and 11 ( 6.4 % )
VF . -
pubmed
Fifty - six out of 67 ( 83.5 % ) of these
patients arrived at Accident & amp ; Emergency ( A&E ) within the first six hours of onset of
chest pain . -
pubmed
Ten out of 11 ( 91 % )
patients who had
VF did so in the first six hours . -
pubmed
Forty - three
patients ( 84 % ) who had
PVCs did not develop any further
arrhythmias . -
pubmed
Initial manifestation of acute intestinal
tuberculosis with miliary involvement in an elderly
patient ] . -
pubmed
A mixture of heterotrophic bacteria and collection
strains of
Escherichia coli and
Pseudomonas fluorescens were immobilized in
calcium alginate or pectate gels . -
pubmed
Despite the improved response rate , high - dose chemotherapy has resulted in short response durations and no significant impact on the survival of
cancer patients as yet . -
pubmed
[
Poisoning with
aliphatic hydrocarbons in
children ] . -
pubmed
This case demonstrates that in a
patient with intermittent
left bundle branch block a complete
AV block may occur and therefore the possibility of cardiopulmonary resuscitation and temporary pacing has to be taken in account . -
pubmed
Using programmed ventricular stimulation , which can detect significant
ventricular arrhythmias in
patients with very little ectopy in 24 - hour electrocardiographic recordings , 20 % of patients have
ventricular tachycardia 2 to 6 weeks after
acute myocardial infarction (
AMI ) . -
pubmed
This finding provides a rationale for treating
patients with frequent or repetitive
ventricular arrhythmias detected near the time of hospital discharge after
AMI . -
pubmed
Lacking an answer to this question and given the frequency of adverse effects with antiarrhythmic drugs , most physicians are conservative in the treatment of
patients with
ventricular arrhythmias after
AMI . -
pubmed
[ Chronic
upper airway obstruction in 2
children ] . -
pubmed
Effects of x - irradiation and
cortisone treatment of
albino rats on
infections with Brucei - complex trypanosomes . -
pubmed
Distribution of bronchial resistance in
obstructive pulmonary diseases and in
dogs with artificially induced
tracheal collapse . -
pubmed
Membrane lipid analyses and electron spin resonance ( ESR ) studies of membrane fluidity were carried out on the red cells of a
Japanese patient with
hereditary high red cell membrane phosphatidylcholine hemolytic anemia (
HPCHA ) . -
pubmed
By analysis of a series of
somatic cell hybrids derived by fusion of either
mouse or Chinese hamster cells with leukocytes from different
chronic myelocytic leukemia (
CML ) patients or from normal donors , we have localized the
human oncogene , c - sis , on the q11 to qter segment of chromosome 22 and demonstrated its translocation from chromosome 22 to chromosome 9 ( q34 ) in
CML . -
pubmed
3.1.1.8 ) ; the activity of both enzymes was raised in amniotic fluid from
women carrying open
NTDs . -
pubmed
Experimental
enteritis in
cynomolgus monkeys produced by intragastric administration of
Salmonella typhimurium . -
pubmed
The protein binding of
piretanide was assessed by continuous ultrafiltration of sera from six normal
subjects and seven
uraemic subjects ( samples taken immediately pre - dialysis ) . -
pubmed
The three
5 - O - acetylated 6 - O - acylated dipeptidyl furanose derivatives also significantly stimulated production of circulating antibodies against
hepatitis B vaccine in
mice ; titers were comparable to those observed with the alum - adsorbed vaccine . -
pubmed
Polyuria above 3 litres/24 hours was found in 10 % of
patients . -
pubmed
Structural studies of the
saccharide part of the cell envelope
lipooligosaccharide from
Haemophilus influenzae strain galEgalK. -
pubmed
The structure of the
saccharide part of the
lipooligosaccharide from
Haemophilus influenzae strain galEgalK has been investigated . -
pubmed
Chronic protein restriction does not alter energetic efficiency or brown adipose tissue thermogenic capacity in genetically
obese ( fa / fa ) Zucker
rats . -
pubmed
Attenuated regulatory thermogenesis in genetically
obese ( fa / fa ) Zucker
rats involves an impaired capacity to increase sympathetic drive to brown adipose tissue in response to dietary stimuli . -
pubmed
Young , growing lean
rats fed a low protein diet reduce energetic efficiency to compensate for elevated energy intake ; however , it is not known if
obese rats adapt similarly to chronic protein restriction by decreasing energetic efficiency and whether this would be accompanied by increased brown adipose tissue thermogenic capacity . -
pubmed
Lean ( Fa / Fa ) and
obese Zucker
rats were either protein - restricted ( protein 8 % of total energy ) or fed a control diet ( 21 % protein ) starting at age 5 wk . -
pubmed
, food intake /
body weight 0.67 ) was greater in protein - restricted than in control lean
rats , but not different due to diet in
obese rats . -
pubmed
Mass - adjusted brown adipose tissue uncoupling protein levels were more than 100 % greater in protein - restricted vs. control lean
rats , but not different between protein - restricted and control
obese rats . -
pubmed
The uncoupling protein level was not significantly different in control lean vs.
obese rats . -
pubmed
Energetic efficiency was 40 % lower in protein - restricted vs. control lean , but not different in
obese rats ; however , the efficiency of protein utilization was significantly greater in
obese protein - restricted than in
obese control
rats . -
pubmed
Protein efficiency increased to more than two times its original value in
obese ( fa / fa )
rats , but otherwise no metabolic accommodation in the capacity for regulatory thermogenesis was observed in this genotype . -
pubmed
One group consisted of 99
brain - injured patients , while the other consisted of a group of 17 neurologically normal controls . -
pubmed
Central conduction times obtained from the right and left hemispheres were similar in ECMO
patients and were not different from those recorded from a group of
patients suffering
hypoxic - ischemic injuries and a group of normal controls who did not receive ECMO . -
pubmed
The results of this pilot study suggest that SEPs may be employed to evaluate ECMO
patients as they are in other
brain - injured patients . -
pubmed
[ Pediatric nursing at home -- six months of home care for a
patient with
spinal muscular atrophy ] . -
pubmed
Clinical variables and laboratory and histologic findings were evaluated in 53
children with
IgA nephropathy , of whom 44 were followed for a mean period of 6.2 years ( range 1.2 - 14 ) . -
pubmed
At the end of the follow - up 8
patients ( 18.2 % ) had had no
urinary anomalies for at least 1 year ( stage A disease ) , 28 ( 63.6 % ) had microscopic
hematuria with
proteinuria & lt ; 1 g / m2 / day ( stage B ) , 5 ( 11.4 % ) had
proteinuria & gt ; 1 g / m2 / day ( stage C ) , and 3 ( 6.8 % ) had
chronic renal insufficiency ( stage D ) . -
pubmed
Presenting features of gross or microscopic
hematuria without or with
proteinuria ( & lt ; 0.5 g / m2 / day ) correlated ( p & lt ; .001 ) with minimal
glomerular abnormalities at biopsy , whereas
patients with
nephritic syndrome had more severe histologic pictures . -
pubmed
Coumermycin A1 inhibits growth and induces relaxation of supercoiled plasmids in
Borrelia burgdorferi , the
Lyme disease agent . -
pubmed
We have investigated the activity of this
coumarin antibiotic on
Borrelia burgdorferi , a spirochete and the causative agent of
Lyme disease . -
pubmed
Increased pulmonary vascular permeability in
rats with
biliary cirrhosis : role of
thromboxane A2 . -
pubmed
Rats with
liver cirrhosis exhibit arterial
hypoxemia and loss of
hypoxic pulmonary vasoconstriction similar to some
patients with
end - stage liver disease . -
pubmed
Electron - microscopic sections of lungs from
cirrhotic rats demonstrated infiltration with intravascular macrophage - like cells , endothelial cell
injury , and interstitial
edema . -
pubmed
We conclude that pulmonary vascular permeability is increased in
rats with
biliary cirrhosis and that
thromboxane A2 contributes to the
pulmonary circulatory abnormalities in
cirrhosis . -
pubmed
Glycolipid compositions of cells infected by
human retroviruses (
human immunodeficiency virus ,
HIV and/or
human T - cell lymphotropic virus type I , HTLV - I ) have been studied . -
pubmed
METHOD : Twelve
schizophrenic patients and 11 comparison
subjects underwent functional MRI of the frontal and temporal lobes . -
pubmed
CONCLUSIONS : These preliminary data suggest that functional MRI has the sensitivity to detect differences in activation between comparison subjects and
schizophrenic patients during higher cortical functions . -
pubmed
These findings are in agreement with PET studies that reported reduced left frontal activation during challenge paradigms for the
schizophrenic patients . -
pubmed
In females , there was an increase primarily in the incidence of
tobacco - related morphologic
tumour types ( i.e. -
pubmed
In 641
patients ( 20 % ) a surgical
tumour resection was carried out . -
pubmed
[
Nedocromil sodium as a topical treatment of
allergic conjunctivitis due to
grasses ] . -
pubmed
Thirty - two
patients ( 20
males and 12 females , mean age 31 ys ) with
seasonal allergic conjunctivitis to
grass pollen , were selected for this study . -
pubmed
Nedocromil sodium is therefore a valid alternative in the treatment of
allergic conjunctivitis to
grass pollen . -
pubmed
RESULTS : The patient population included 124
patients , 75 men and 49 women with a mean age of 48.4 years and a mean
arthritis duration of 14.6 years . -
pubmed
Other studies have found that the morphology of
rat stellate
ganglion neurones is similar to that of superior cervical
ganglion cells . -
pubmed
However , in
strains of
rat displaying spontaneous
hypertension , dendritic length may be increased . -
pubmed
A
patient with left
unilateral neglect and a slight
left hemiparesis participated in three experiments . -
pubmed
METHODS : Data from a total of 224
patients with
BD , diagnosed between 1982 and 1996 , were analyzed retrospectively . -
pubmed
MATERIALS AND METHODS : From August 1990 to April 1994 , 32
patients bearing previously untreated advanced
squamous cell carcinoma of the larynx ( 12 stage III and 20 stage IV ) received three courses of high - dose
cisplatin ( 100 mg / m2 on day 1 and day 8 every 28 days ) before definitive external radiation therapy with 65 to 70 Gy ( 180 - 200 cGy daily for 6 - 8 weeks ) . -
pubmed
RESULTS : With an average follow - up time of 18 months ( range , 6 - 47 ) , 30
patients are evaluable for response and 32 for
toxicity . -
pubmed
The main acute
toxicity was grade 2 - 3
nausea and
vomiting in 75 % of
patients . -
pubmed
Two
patients developed
renal impairment after the first course of
cisplatin . -
pubmed
Ototoxicity ( grade 2 - 3 ) was seen in 43 % of
patients , and
peripheral neuropathy ( grade 2 - 3 ) was observed in 12 % of
patients . -
pubmed
Bacterial keratitis after photoreactive keratectomy in a young , healthy
man . -
pubmed
In a
rabbit model of chronic ileal
inflammation , we previously demonstrated that coupled
NaCl absorption was reduced because of an inhibition of
Cl-/
HCO3 - but not
Na+/
H+ exchange on the brush - border membrane ( BBM ) of villus cells . -
pubmed
PATIENTS : One hundred twenty - five
patients in whom
cirrhosis was discovered during gastric bariatric operations . -
pubmed
MATERIALS AND METHODS : A stone - forming
rat model ( model 1 ) with marked tubular dilatation in an entire kidney was produced by rendering
Wistar rats ( aged 8 weeks )
hyperoxaluric and
hypercalciuric , through compulsorily feeding with 0.12 mL of 5 %
ethylene glycol ( in two doses daily ) and 0.5 microgram of
vitamin D3 every other day . -
pubmed
Peripheral venous blood and subdural fluid were obtained at the time of burr hole surgery from 34
patients with
CSH and from 9 with
subdural effusion . -
pubmed
Agents that have received the most attention include
ozone ,
nitrogen dioxide ,
hyperoxia , diesel exhaust ,
tobacco smoke ,
silica and fibrous materials such as asbestos . -
pubmed
Animal models for
motor neuron disease . -
pubmed
At present , there is no cure for most
motor neuron diseases , including
amyotrophic lateral sclerosis (
ALS ) , the most common
human motor neuron disease -- the cause of which remains largely unknown . -
pubmed
Animal models of
motor neuron disease (
MND ) have significantly contributed to the remarkable recent progress in understanding the cause , genetic factors , and pathologic mechanisms proposed for this class of
human neurodegenerative disorders . -
pubmed
Largely driven by
ALS research ,
animal models of
MND have proven their usefulness in elucidating potential causes and specific pathogenic mechanisms , and have helped to advance promising new treatments from " benchside to bedside . " -
pubmed
This review summarizes important features of selected established
animal models of
MND : genetically engineered
mice and inherited or spontaneously occurring
MND in the
murine ,
canine , and
equine species . -
pubmed
Effect of
gentian violet ,
corticosteroid and tar preparations in
Staphylococcus - aureus - colonized
atopic eczema . -
pubmed
BACKGROUND : In
atopic eczema (
AE ) , skin colonization with
Staphylococcus aureus plays a possible role in the pathophysiology of the disease . -
pubmed
METHODS : Thirty - eight
patients with
AE were screened for their cutaneous colonization with
S. - pubmed
IMT measurements were determined by high resolution B - mode ultrasound imaging of the carotid arteries in 921
participants with
NIDDM and 11,964 non - diabetic
participants aged 45 - 64 years . -
pubmed
BACKGROUND : Detection of occult
micrometastasis in regional lymph nodes is crucial for diagnosis and selection of appropriate therapy for
patients with pN0
non - small - cell lung carcinoma . -
pubmed
Using immunohistochemical staining , we evaluated the impact of detection of occult micrometastasis on the prevalence and prognosis of
patients with
lung adenocarcinoma of 2.0 cm or less in diameter . -
pubmed
METHODS : A total of 103 pN0 disease
patients with
peripheral lung adenocarcinomas of 2.0 cm or less in diameter were enrolled in this study . -
pubmed
RESULTS :
Micrometastasis was detected in 49 lymph nodes ( 3.4 % ) of 21
patients ( 20.4 % ) but not in
patients with localized
bronchioloalveolar carcinoma or localized
bronchioloalveolar carcinoma with foci of collapse of alveolar structure . -
pubmed
The 5 - year survival rate ( 61.9 % ) of
patients with
micrometastasis was significantly ( p = 0.0041 ) lower than that of
patients without
micrometastasis ( 86.3 % ) . -
pubmed
MATERIALS AND METHODS : We studied the activities and mRNA expression levels of these enzymes in normal
human livers and in
human livers with
chronic hepatitis ,
cirrhosis , or
hepatocellular carcinoma . -
pubmed
In the present investigation , we test the hypothesis that
progesterone can rapidly relax , via a nongenomic mechanism , persistent flow occluding , agonist - activated coronary artery ( CA )
vasospasm , and hyperreactive vascular muscle cell ( VMC )
Ca ( 2 + ) responses in ovariectomized
rhesus monkeys . -
pubmed
Hypotension is a common
postoperative complication in the perianesthesia setting and contributes to increased
patient morbidity and mortality rates . -
pubmed
Prospective evaluation of
pain relief in 100
patients undergoing percutaneous vertebroplasty : results and follow - up . -
pubmed
Before the procedure and at follow - up ,
patients were asked to quantify their
pain on a visual analog scale ( VAS ) and complete a follow - up questionnaire of our own design . -
pubmed
One
patient sustained a
sternal fracture and one experienced a transient
radiculopathy . -
pubmed
Ninety - seven
patients ( 97 % ) reported significant
pain relief 24 hours after treatment . -
pubmed
Ninety - two
patients ( 93 % ) reported significant improvement in
back pain previously associated with their
compression fractures as well as improved ambulatory ability . -
pubmed
CONCLUSION : Percutaneous vertebroplasty of symptomatic vertebral body compression
fractures is a minimally invasive procedure that provides immediate and sustained
pain relief in
patients with
refractory pain . -
pubmed
Genetic diversity of
echovirus 30 during a
meningitis outbreak , demonstrated by direct molecular typing from cerebrospinal fluid . -
pubmed
Echovirus 30 is one of the enterovirus serotypes isolated most frequently in
meningitis cases . -
pubmed
The viral sequences obtained for 22 patients were compared with those of virus isolates obtained from nine patients with
echovirus 30 meningitis admitted to hospital in 1996 - 1997 and with
echovirus 30 sequences from international databases . -
pubmed
Untreated allografted
rats developed
proteinuria ,
glomerulosclerosis , and mild
intimal hyperplasia . -
pubmed
However , parental administration has negative aspects such as multiple injections , possible
infection ,
patient inconvenience , and high cost . -
pubmed
Cerebral blood flow and hemodynamics in
patients with
dizziness resulting from
central nervous system disorders . -
pubmed
OBJECTIVE : To investigate the changes in regional cerebral blood flow ( RCBF ) and cerebral hemodynamics in
patients with
dizziness resulted from
disorders of the central nervous system . -
pubmed
METHOD : Using
133Xe inhalation technique and transcranial Doppler ultrasonography(TCD ) , we measured RCBF and blood flow velocity in the major cerebral arteries in 86 such
patients with
dizziness , who were divided into persisting and intermittent groups according to the symptoms . -
pubmed
RESULT : Decreased RCBF was found in 60.5 % of the
patients with also lowered cerebral blood flow velocity , and the abnormalities appeared more serious when the
dizziness persisted . -
pubmed
CONCLUSION : Measurement of RCBF and cerebral blood velocity in
patients with central nervous system - related
dizziness but without cerebral structural changes may facilitate the assessment of the degree of pathological changes in RCBF and hemodynamics in the affected area and help to better understand the patterns of these changes , which may consequently assist clinical decisions on the diagnosis and treatment of the disease . -
pubmed
[ Isolation of
17 - ketosteroids from the daily urine of
patients with
chronic tonsillitis ] . -
pubmed
We report a 19 - year old
woman with
lupus nephritis and
nephrotic syndrome who had not achieved complete remission after treatment with 15.7 g
cyclophosphamide and 13.7 g
prednisone . -
pubmed
OBJECTIVE : To determine , in spontaneously
hypertensive rats ( SHR ) and Wistar - Kyoto ( WKY )
rats , whether acute reductions of the HR in response to
ivabradine induced changes in the carotid visco - elastic behavior , as assessed by echo - tracking techniques . -
pubmed
Tissue reactions to waxes derived from spool
cotton ; possible etiologic relation to suture
granulomas and suture extrusion . -
pubmed
The
mammalian lignan
enterolactone (
ENL ) , which is produced from dietary
plant -
lignan precursors by the intestinal microflora , may protect against
breast cancer and other
hormone - dependent cancers . -
pubmed
In conclusion , whole grains and
vegetables are the most important dietary providers of plant
lignans for the concentration of ENL in Danish postmenopausal women , and if ENL is found to protect against
cancer or
heart disease , the intake of whole grains and
vegetables should be increased . -
pubmed
METHODS : Of 84
patients with histologically proven
HCC by hepatectomies , multiphasic helical CT demonstrated 54
HCC lesions of intrahepatic
recurrence in 31 ( 37 % )
patients . -
pubmed
Does
donepezil treatment slow the progression of
hippocampal atrophy in
patients with
Alzheimer ' s disease ? -
pubmed
METHOD : In a prospective cohort study , 54
patients with
Alzheimer ' s disease who received
donepezil treatment and 93 control
patients with
Alzheimer ' s disease who never received anti -
Alzheimer drugs underwent magnetic resonance imaging ( MRI ) twice at a 1 - year interval . -
pubmed
METHODS : Forty two specimens of
colorectal cancer and
normal colorectal mucosa were investigated , taken from the colon or rectum in group of
colorectal cancer patients . -
pubmed
OBJECTIVE : To assess
benign prostatic hyperplasia (
BPH ) and
erectile dysfunction (
ED ) , both considered to be associated with urogenital ageing , in ageing
men in a cross - sectional population study , comparing them with healthy controls by using symptom scores and contrast - enhanced colour Doppler ultrasonography ( CDUS ) . -
pubmed
CDUS was performed using the microbubble - based ultrasound enhancer for evaluating prostate , bladder neck and corpus cavernosum vascularity in young healthy
men ,
men with
BPH , and
men with severe
vascular damage (
diabetes mellitus type 2 ) . -
pubmed
RESULTS : In
patients with
BPH , perfusion of the transition zone ( TZ ) of the prostate was significantly lower and the resistive index of the TZ significantly higher ( both P & lt ; 0.001 ) than in healthy controls . -
pubmed
In
patients with
BPH the IPSS , quality - of - life and IIEF scores were significantly worse than in the control group . -
pubmed
Twelve ( 7 male and 5 female )
athletes were randomly assigned into two groups and spent 8 h per night for two consecutive nights a week over 3 weeks under either short - term normobaric
hypoxia ( simulating 3636 m altitude , inspired
O2=13 % ) or in normobaric normoxia in a single - blind study . -
pubmed
The
patients at risk for
infection were given
valgancyclovir as prophylaxis throughout the study . -
pubmed
[ Effect of
glutamine depletion on immunity and other organ function in
critically ill patients ] . -
pubmed
OBJECTIVE : To evaluate the effect of
glutamine depletion on immunity and other organ function in
critically ill patients . -
pubmed
CONCLUSION : In
critically ill surgical
patients glutamine depletion is evident , and the reduction in plasma
Gln is related to immunosuppression and
organ dysfunction . -
pubmed
METHODS : Observational descriptive study of 16 ( sixteen ) eyes of 16
patients with unilateral
acute central serous chorioretinopathy . -
pubmed
RESULTS : Of the 16 central
serous chorioretinopathy eyes , 12
patients completed follow - up until total resolution of their disease . -
pubmed
Pineal parenchymal tumour of intermediate differentiation (
PPTID ) in
adults is rare and a treatment strategy for this condition has not yet been established . -
pubmed
This 60 - year - old
man presented with a 3 - month history of
memory disturbance ,
gait instability and
double vision . -
pubmed
Little is known about the clinical behaviour of
PPTID in
adults . -
pubmed
[ Researching the influence of animal feed in
dogs with a
congenital porto - systemic shunt ] . -
pubmed
Intravenous
glutamine supplementation to
head trauma patients leaves cerebral
glutamate concentration unaffected . -
pubmed
nutrition for neurosurgical
patients , as this may result in elevated intracerebral
glutamate levels , which are thought to be associated with
neuronal injury and cell swelling , causing an increase in ICP and an unfavourable outcome . -
pubmed
SUBJECTS :
Patients with severe
head trauma ( GCS<or=8 ; n=15 ) on routine monitoring , including intracerebral microdialysis , were randomly assigned to treatment followed by placebo or placebo followed by treatment . -
pubmed
We report a
patient with chemotherapy - naive advanced
pancreatic cancer having multiple
liver metastases which dramatically responded to
S-1 , an oral
fluoropyrimidine . -
pubmed
Gene expression profiling of islets from pre - diabetic male Zucker diabetic fatty ( ZDF )
rats showed increased expression of
hypoxia - related genes , prompting investigation of the vascular integrity of the islets . -
pubmed
These data suggest that in the ZDF
rat model of
type 2 diabetes , an inability of the islet to maintain vascular integrity may contribute to beta - cell failure . -
pubmed
We present two
children discovered to have a total
cataract in one eye with a
posterior subcapsular cataract in the other eye . -
pubmed
We conclude that the
pulmonary infection of
M. - pubmed
This presents a proof of concept for device based baroreflex modulation in acute BP regulation and adds to the available data which provide a rationale for evaluating this system in the context of chronic BP reduction in
hypertensive patients . -
pubmed
Spores of 11 enterotoxigenic
strains of
Bacillus cereus isolated from foods and
humans adhered with similar efficiencies to
Caco-2 cells , whereas subsequent germination triggering was observed with only 8 of these
strains . -
pubmed
Time to coronary angiography and outcomes among
patients with high - risk non ST - segment elevation
acute coronary syndromes : results from the SYNERGY trial . -
pubmed
BACKGROUND : Optimal timing for an early invasive strategy in
patients with non - ST - segment - elevation
acute coronary syndrome remains unclear . -
pubmed
We evaluated the relationship between time from hospital admission to coronary angiography and outcomes in high - risk
patients with non - ST - segment - elevation
acute coronary syndrome who underwent angiography within 48 hours of admission . -
pubmed
The adjusted odds ratio for death /
myocardial infarction in
patients receiving angiography in & lt;6 hours was 0.56 ( 95 % confidence interval 0.41 to 0.74 ) , whereas after 30 hours , there was no significant benefit compared with further delayed angiography . -
pubmed
COLOBOMATA OF THE OPTIC NERVE SHEATH IN
RATS . -
pubmed
[
Cardiac symptoms due to
pectus excavatum in a
man over the age of 55 ] . -
pubmed
A healthy 59 - year - old
man , a retired general practitioner , suffered from increasing
palpitations ,
fatigue and
postural dyspnoea : bending over led to a significant increase in his
shortness of breath . -
pubmed
[ Effect of the
acetylosalicyd acid (
ASA ) and
ticlopidine therapy on clinical condition and parameters of blood platelets in
patients with
peripheral arterial occlusive disease (
PAOD ) ] . -
pubmed
RESULTS : Supplementation therapy with
ASA or
ticlopidine to the standard therapy with
pentoxyphylline resulted in a marked increase in the distance of
claudication evaluated subjectively and objectively on moving track and revealed silent
myocardial ischemia in 4
PAOD patients . -
pubmed
CONCLUSIONS : Both antiplatelet drugs have beneficial effect on clinical condition of
PAOD patients and the effect may results from their anti - aggregative and anti - adhesive properties . -
pubmed
One hundred non - dialysis
patients with
chronic kidney disease over 18 years of age were evenly split into anemic and non - anemic cohorts . -
pubmed
Of the 50
anemic patients , 23 were receiving erythropoiesis stimulating agents treatments . -
pubmed
METHODS : Ninety - two
steroid - naive and twenty - eight
steroid - treated
asthmatic patients were enrolled . -
pubmed
FU + L (
FUL ) are frequently combined with
oxaliplatin (
OXA ) in advanced
colon cancer patients . -
pubmed
Prognostic value of intra - operative lateral spread response monitoring during microvascular decompression in
patients with
hemifacial spasm . -
pubmed
Among these 32
patients , 11 had mild
HFS at discharge and six had mild
HFS at the 6 month follow up . -
pubmed
Out of the 40
patients in whom the LSR disappeared intra - operatively after MVD , five had mild
HFS at discharge and four had mild
HFS at the 6 - moth follow up . -
pubmed
Tailoring treatment according to risk of
disease recurrence ,
patient life expectancy , comorbidity , risk factors for
cardiovascular disease or
osteoporosis and compliance is necessary . -
pubmed
Rearrangement of the JC virus regulatory region sequence in the bone marrow of a
patient with
rheumatoid arthritis and
progressive multifocal leukoencephalopathy . -
pubmed
The
polyomavirus JC (
JCV ) is the etiologic agent of
progressive multifocal leukoencephalopathy (
PML ) . -
pubmed
Further studies will be needed to determine the prevalence of
JCV in bone marrow of immunosuppressed individuals at risk of
PML and characterize the RR and phenotype of these
JCV isolates . -
pubmed
Immune responses of
humans and animals are impaired by
sleep loss , and responses to immune challenge include altered sleep . -
pubmed
Ribotyping , biotyping and capsular typing of
Haemophilus influenzae strains isolated from patients in Campinas , southeast Brazil . -
pubmed
Forty - five
Haemophilus influenzae strains isolated from patients were characterized based on biochemical characteristics . -
pubmed
Placental transmogrification of the lung has been considered a variant of unilateral
bullous emphysema , but in our case , the patient was a 47 - year - old
man who had no coexisting
emphysema of the lung . -
pubmed
Hydrogen - rich saline reduces
lung injury induced by intestinal
ischemia / reperfusion in
rats . -
pubmed
In this study we investigated the effects of
hydrogen - rich saline on the prevention of
lung injury induced by intestinal
ischemia / reperfusion ( I / R ) in
rats . -
pubmed
BACKGROUND : Though antidepressant drugs are the treatment of choice for severe
major depression , a number of
patients do not improve with pharmacologic treatment . -
pubmed
This study aimed to assess the effects of transcranial direct current stimulation ( tDCS ) in
patients with severe , drug - resistant
depression . -
pubmed
CONCLUSIONS : We conclude that frontal tDCS is a simple , promising technique that can be considered in clinical practice as adjuvant treatment for hospitalized
patients with severe , drug - resistant
major depression . -
pubmed
Pharmacokinetics of
ceftriaxone in
carbontetrachloride - induced
hepatopathic and
uranyl nitrate - induced
nephropathic goats following single dose intravenous administration . -
pubmed
The pharmacokinetic profile of
ceftriaxone was studied in female healthy
goats , induced
hepatopathic and
nephropathic goats after a single intravenous dose at 50 mg kg(-1 ) . -
pubmed
Ceftriaxone persisted for 2 h in plasma of
hepatopathic goats compared to 1 h of healthy
goats , but the kinetic behaviour followed ' one - compartment open model ' in both healthy and
hepatopathic goats . -
pubmed
Ceftriaxone was recovered at 24 h in urine of
hepatopathic goats but it could not be detected in urine of healthy
goats . -
pubmed
However , its metabolite
ceftizoxime was present in urine of healthy
goats but not in urine of
hepatopathic goats . -
pubmed
Elimination halflife ( t(1/2)beta ) of Elimination
ceftriaxone ( 0.38 + /- 0.01 h ) in
nephropathic goats increased significantly compared to healthy
goats ( 0.19 + /- 0.002 h ) . -
pubmed
PATIENTS / MATERIALS AND METHODS : 226
patients with
exsudative AMD and 179 controls without
AMD were included . -
pubmed
Failure of
tooth eruption in two
patients with
cerebral palsy and
bruxism - a 10 - year follow - up : a case report . -
pubmed
The aim of this paper was to analyze delayed
tooth eruption in two
children with
cerebral palsy who had severe
bruxism and to determine whether treatment could influence tooth eruption and alignment . -
pubmed
Bariatric surgery was cost - effective at 2 years for management of
type 2 diabetes in obese
patients . -
pubmed
Off - pump coronary artery bypass grafting no - touch surgery can be the treatment of choice for
patients with three - vessel disease and
left main stenosis . -
pubmed
Peripheral edema is a common and dose - dependent adverse event seen with
dihydropyridine CCBs , which can cause marked
patient distress , reduce adherence to therapy , and result in dose reduction or even discontinuation of therapy . -
pubmed
The protective role of
anandamide in
mesenteric ischemia reperfusion injury in
guinea pig . -
pubmed
Women in the continuous group reported significantly fewer
bleeding days requiring protection and were more likely to have
amenorrhea ; in addition they also reported significantly fewer days of
bloating and
menstrual pain . -
pubmed
At the end of the 1 - year trial
amenorrhea was present in 58.7 % of the
women and a complete absence of
bleeding in 79.0 % . -
pubmed
METHODS : Fifteen
patients ( mean age , 41.9 years ) who had symptomatic
osteochondral lesions of the talus with a mean volume of 6059 mm(3 ) underwent fresh matched osteochondral allograft transplantation . -
pubmed
All
patients were followed prospectively for a minimum of two years and were evaluated with use of the
pain score on a visual analog scale , which ranged from 0 to 10 , and the American Orthopaedic Foot and Ankle Society ankle - hindfoot score , which had a maximum of 100 points . -
pubmed
With the scores for these
patients included ( at the time of arthrodesis ) , the mean
pain score had improved from 8.5 to 3.3 and the mean American Orthopaedic Foot and Ankle Society ankle - hindfoot score had improved 45 points , from 38 to 83 points . -
pubmed
We analyzed miRNA expression profiles in 25 pairs of
HCC and adjacent
non - tumor liver tissues from
HCC patients using miRNA microarray . -
pubmed
A case of
multiple organ tuberculosis (
TBc ) involving lung , pleura , and peritoneum in a 39 - year - old
man with long - standing
ankylosing spondylitis (
AS ) treated with
adalimumab was presented . -
pubmed
METHODS : Immunohistochemical staining was performed on pelvic autonomic nerve specimens resected from 17
patients with p - Stage I - III lower rectal
cancers . -
pubmed
This report presents the case of a 20 - year - old female
patient exhibiting an
infraoccluded ankylosed maxillary central incisor that was avulsed and replanted after
traumatic injury during childhood . -
pubmed
Invasion of red blood cells ( RBCs ) by the
Plasmodium falciparum malaria merozoite is mediated by parasite surface molecules and proteins contained within apical organelles that are capable of recognizing receptors on the membrane of RBCs . -
pubmed
Acute renal dysfunction in a
patient presenting with
rhabdomyolysis due to
Hypothyroidism attributed to
Hashimoto ' s Disease . -
pubmed
We describe a
patient with
rhabdomyolysis and
acute renal dysfunction due to
hypothyroidism , attributed to
Hashimoto ' s disease . -
pubmed
The disease
malaria , caused by the parasite
Plasmodium falciparum , remains one of the most important causes of morbidity and mortality in sub - Saharan Africa . -
pubmed
Our findings open the door to development of new drugs and patents , especially for CMTs that lack antibiotic activity ( US 7649113 ) , for treatment of
human allergic disease . -
pubmed
Does antiepileptogenesis affect sleep in genetic
epileptic rats ? -
pubmed
Recently it was established that early long lasting treatment with the anti - absence drug
ethosuximide (
ETX ) delays the occurrence of absences and reduces
depressive - like symptoms in a genetic model for
absence epilepsy ,
rats of the WAG / Rij
strain . -
pubmed
Renal complications correlate with electrical atrial vulnerability hallmarks in
type 2 diabetic patients . -
pubmed
INTRODUCTION :
Liver cirrhosis has been shown to be associated with impaired outcome in
patients who underwent elective surgery . -
pubmed
We therefore investigated the impact of
alcohol abuse and subsequent
liver cirrhosis on outcome in multiple
trauma patients . -
pubmed
MATERIALS AND METHODS : Using the multi - centre population - based
Trauma Registry of the German Society for
Trauma Surgery , we retrospectively compared outcome in
patients ( ISS & gt;= 9 , & gt;= 18 ) with pre - existing
alcohol abuse and
liver cirrhosis with healthy
trauma victims in univariate and matched - pair analysis . -
pubmed
CONCLUSIONS :
Patients suffering from
liver cirrhosis presented impaired outcome after
multiple injuries . -
pubmed
Spray - applied cell therapy with
human allogeneic fibroblasts and keratinocytes for the treatment of chronic
venous leg ulcers : a phase 2 , multicentre , double - blind , randomised , placebo - controlled trial . -
pubmed
BACKGROUND : Many
patients with
venous leg ulcers do not heal with standard care . -
pubmed
METHODS : We enrolled adult
outpatients from 28 centres in the USA and Canada with up to three
ulcers ,
venous reflux confirmed by doppler ultrasonography , and adequate arterial flow in this phase 2 , double - blind , randomised , placebo - controlled trial if at least one
ulcer measured 2 - 12 cm(2 ) in area and had persisted for 6 - 104 weeks . -
pubmed
Adverse events were much the same across all groups , with only new
skin ulcers and
cellulitis occurring in more than 5 % of
patients . -
pubmed
These have greatly improved the outlook and prognosis for
diabetic patients with
ischemic foot problems . -
pubmed
A
stroke patient with
impairment of auditory sensory ( echoic ) memory . -
pubmed
Here , we have investigated the re - innervation patterns of epidermal and dermal nerve fibers in a
rat neuropathic pain model . -
pubmed
Generally 18
patients out 37
patients referred with biochemical
relapse were confirmed to have bone involvement . -
pubmed
Selection for qacA carriage in
CC22 , but not
CC30 ,
methicillin - resistant
Staphylococcus aureus bloodstream infection isolates during a successful institutional
infection control programme . -
pubmed
BACKGROUND :
Syncope ,
dyspnea , and
chest pain are well - established indications for aortic valve replacement in
patients with severe
AS . -
pubmed
Patients ' survival is limited once they develop symptoms from
AS , and survival depends on what type of symptoms a patient develops . -
pubmed
METHODS : We analyzed 498
patients (
men : 58.4 % , 66 + - 12 years of age ) with severe
AS and normal left ventricular ejection fraction from 2003 to 2009 who had comprehensive echocardiography examination for
AS . -
pubmed
Compared with the asymptomatic group , symptomatic
patients were older and had
lower cardiac output , and higher E / e ' ratio while having a similar aortic valve area and gradient . -
pubmed
Pennyroyal was thought to prevent
infection and
potatoes were used to relieve
pain . -
pubmed
PATIENTS : Twenty - six
patients with
CIS /
MS in active
relapse , 10
patients with other
autoimmune disorders , 12
patients with
neuroinfectious diseases , and 15
patients with noninflammatory
neurological diseases . -
pubmed
Cohort studies have shown that
vegetables and fruits protect against
coronary heart disease , whereas whole grains provide protection against
cardiovascular disease ,
type 2 diabetes , and
weight gain . -
pubmed
Randomised clinical trial : evaluation of the efficacy of
mesalazine (
mesalamine ) suppositories in
patients with
ulcerative colitis and active rectal
inflammation -- a placebo - controlled study . -
pubmed
Mild - to - moderate
UC patients with rectal
inflammation were randomly assigned either a 1 g
mesalazine or placebo suppository . -
pubmed
The percentage of
patients without
bleeding was significantly higher in the
mesalazine group than the placebo group from Day 3 of treatment ( P = 0.0001 , Fisher 's exact test ) . -
pubmed
CONCLUSIONS : The effectiveness of
mesalazine suppositories in all types of
UC patients with rectal
inflammation was confirmed for the first time in a double - blind , placebo - controlled , parallel - group study ( JapicCTI- 111421 ) . -
pubmed
Ultrasound guided brachial plexus block can be advantageous in
patients with
avulsion type upper extremity injuries . -
pubmed
This report describes a 43 - year - old
patient who , after allogeneic bone marrow transplantation , developed an
oral squamous cell carcinoma secondary to the use of
azathioprine ,
cyclosporine ,
prednisone , and
tacrolimus , associated with multiorgan
chronic graft - versus - host disease involving the oral mucosa , skin , eyes , and liver . -
pubmed
This report aims to discuss the possible role of immunosuppressant therapy for
chronic graft - versus - host disease on the development of
oral squamous cell carcinoma , and the relevance of a close oral follow - up of
patients to detect dysplastic or malignant alterations at an early stage . -
pubmed
Management and treatment of
liver injury in
children . -
pubmed
BACKGROUND : We aimed to assess the causes of
trauma that result in
liver injury and additional
solid organ injuries , management types and results of management in
children referred to our clinic for
liver injuries . -
pubmed
METHODS : The records of 52
patients who were managed for
liver injuries due to
blunt abdominal trauma between January 2005 - 2010 were reviewed retrospectively . -
pubmed
Forty - five
patients ( 87 % ) were managed conservatively in this series of
liver injury , whereas seven patients ( 13 % ) who had unstable vital signs underwent surgery . -
pubmed
CONCLUSION : As a result , conservative management should be preferred in
patients with
liver injuries who are hemodynamically stable . -
pubmed
We aimed to study the clinical , biochemical and extra skeletal manifestations of untreated
CKD -
MBD in pre - dialysis Stage 4 and 5
CKD patients attending nephrology out - patient clinic at a tertiary care hospital in South India . -
pubmed
Of the 710
patients surveyed , 45 % had no
CKD - MBD related symptom . -
pubmed
A
patient with severe
pulmonary hypertension for hip arthroplasty . -
pubmed
The plant pathogenic fungus
Fusarium fujikuroi is the causal agent of
bakanae disease on
rice due to its ability to produce
gibberellins . -
pubmed
Half dosage of this gene in
humans causes most of the features of the
DiGeorge or Velocardiofacial syndrome phenotypes , including
aortic arch and cardiac outflow tract abnormalities . -
pubmed
Silk fibroin nanoparticles constitute a vector for controlled release of
resveratrol in an experimental model of
inflammatory bowel disease in
rats . -
pubmed
PURPOSE : We aimed to evaluate the intestinal anti - inflammatory properties of silk fibroin nanoparticles , around 100 nm in size , when loaded with the
stilbene compound
resveratrol , in an experimental model of
rat colitis . -
pubmed
The biological effects of the
resveratrol - loaded nanoparticles were tested both in vitro , in a cell culture of
RAW 264.7 cells (
mouse macrophages ) , and in vivo , in the
trinitrobenzenesulfonic acid model of
rat colitis , when administered intracolonically . -
pubmed
The moderate negative correlation pairs ( rp ) between remaining
Alcian blue and amount of
Na (+ ) adsorbed on EPS from
strains TN114 and
PP803 were -0.652 and -0.609 . -
pubmed
The principal component from EPS of
strain PP803 which was responsible for salt removal was purified and it was identified as a polysaccharide ( 18 kDa ) mainly composed of
galacturonic acid . -
pubmed
Important recent advances include the development of
mouse models and patient - derived induced pluripotent stem cell ( iPSC ) lines that enable a detailed investigation of
synaptic deficits and the identification of potential targets for therapy . -
pubmed
In these extended studies the analgesic activity of two tested compounds ( 4c , 4f ) was confirmed in some
animal models of
pain . -
pubmed
Both compounds decreased the
edema formation and one of them ( 4c ) attenuated mechanical
hyperalgesia in carrageenan - induced paw
inflammation in
rats . -
pubmed
Furthermore , both compounds inhibited cell migration , plasma exudation and nociceptive reaction in zymosan A - induced
mouse peritonitis . -
pubmed
In the present study , we examined whether oral administration of
MA128 suppressed the in vivo
tumor growth of
HT1080 cells in athymic
nude mice . -
pubmed
In particular , none of the
mice treated with
MA128 exhibited
systemic toxicity , such as body
weight loss or
liver and kidney dysfunction . -
pubmed
Susceptibility to antimicrobials of
mastitis - causing
Staphylococcus aureus ,
Streptococcus uberis and
Str . - pubmed
OBJECTIVE : To compare the antimicrobial susceptibility patterns of three common
mastitis pathogens (
Staphylococcus aureus ,
Streptococcus uberis and
Str . - pubmed
Long - term prognostic significance of admission plateletcrit values in
patients with non - ST elevation
myocardial infarction . -
pubmed
The objective of our study was to investigate the role of admission plateletcrit in predicting long - term cardiovascular mortality in
patients presenting with
non - ST - segment elevation myocardial infarction (
NSTEMI ) . -
pubmed
We enrolled 296
patients with
NSTEMI ( mean age 59.2 + - 11.8 years ; 228 men , 68
women ) in this study . -
pubmed
Long - term major advanced cardiac events ( MACE ) , hospitalization for
heart failure and
reinfarction were significantly higher in
patients with high plateletcrit . -
pubmed
Admission plateletcrit is a strong and independent predictor of long - term cardiovascular mortality in
patients with
NSTEMI . -
pubmed
Reduction of body fat and improved lipid profile associated with daily consumption of a
Puer tea extract in a
hyperlipidemic population : a randomized placebo - controlled trial . -
pubmed
OBJECTIVE : The goal for this study was to evaluate the effects of daily consumption of
Puer tea extract ( PTE ) on
body weight , body - fat composition , and lipid profile in a non - Asian population in the absence of dietary restrictions . -
pubmed
Analysis of prehospital care and emergency room treatment of
patients with
acute traumatic spinal cord injury : a retrospective cohort study on the implementation of current guidelines . -
pubmed
OBJECTIVES : The aims of the current study were ( i ) to analyze prehospital and emergency room treatment of
patients with acute
traumatic spinal cord injury (
SCI ) and ( ii ) to analyze whether recommendations given by the current guidelines are implemented . -
pubmed
Immobilization was performed on 69.9 % of the
patients with
traumatic SCI . -
pubmed
From 60
patients suffering from
cervical traumatic SCI , 47
patients had a cervical collar . -
pubmed
In this article , we evaluated the sonosensitizing activity and mode of action of
5 - ALA /
PpIX by using
mouse mammary tumor EMT6 cells . -
pubmed
CONCLUSION :
5 - ALA - SDT showed an antitumor effect in
mouse mammary tumor EMT6 cells through oxidation of the mitochondrial membrane via ROS production . -
pubmed
The objective of this study was to determine whether alterations in adipose tissue mass arising from food consumption modify the inflammatory response of antigen - induced
joint inflammation in
mice . -
pubmed
RESULTS : PAT volumes were significantly increased in
patients with chronic
MDD>
patients with acute
MDD>CTRL . -
pubmed
Adrenal gland volume was slightly enlarged in
patients with chronic
MDD>acute
MDD>CTRL , although this difference failed to reach significance . -
pubmed
CONCLUSION : Our results extend the existing literature in demonstrating that
patients with chronic
MDD have the highest risk for developing
cardiovascular disorders , indicated by the highest PAT volume and prevalence of
metabolic syndrome . -
pubmed
Metabolic monitoring , health advices and motivation for the improvement of physical fitness may be recommended in depressed
patients , in particular in
chronic depression . -
pubmed
Pharmacodynamic evaluation was performed using the
MK-801 - induced
schizophrenic behavioural
mouse model , and the sustained suppressive effect lasted two weeks . -
pubmed
A stable drug plasma concentration was detected in
mice both intraday and interday from 8 to 22 d after a single injection of
isoperidone microspheres , and a sustained suppressive effect on the
schizophrenic model was also observed . -
pubmed
METHODS : Forty - eight
patients with
IBD ( 24
ulcerative colitis , 24
Crohn ' s disease ) and 40 matched healthy control individuals were enrolled . -
pubmed
When compared to control group , in
patients with
Crohn ' s disease serum
homocystein levels were significantly higher ( p = 0.025 ) while serum
folic acid levels were significantly lower ( p & lt ; 0.019 ) . -
pubmed
Preliminary assessment of Neck Circumference in
Benign Prostatic Hyperplasia in
Patients with
Metabolic Syndrome . -
pubmed
The
BPH patients were enrolled and were divided into 2 groups : with MtS ( Group 1 ; n=94 ) and without MtS ( Group 2 ; n=103 ) . -
pubmed
RESULTS :
PPD was detected in 70 postpartum
women . -
pubmed
Polymorphonuclear neutrophils ( PMNs ) have previously been reported to mediate phagocytosis of
anti - CD20 - opsonized B cells from
patients with
chronic lymphocytic leukemia (
CLL ) . -
pubmed
We conclude that PMNs mediate mostly trogocytosis rather than phagocytosis of
anti - CD20 - opsonized CLL B cells , and we discuss the implications of this finding in
patients with
CLL treated with rituximab or obinutuzumab in vivo . -
pubmed
A total of nine
patients with stage I , left - sided
breast cancer who underwent breast - conserving surgery were selected for this retrospective study . -
pubmed
At our hospital , we performed a retrospective study of 39
HD and 51 non - HD
patients with echocardiography - confirmed
IE between June 2000 and February 2007 . -
pubmed
The number of patients with
diabetic mellitus in these two groups was significantly different ( 28.2 % HD vs 5.9 % non - HD
patients ) . -
pubmed
By contrast , the erythrocyte sedimentation rate was significantly higher in the
HD patients ( HD vs non - HD : 87.2 + -33.32 vs 52.96 + -28.19 ) . -
pubmed
The
HD patients had a significantly higher
Staphylococcus aureus infection rate ( HD : 46.2 % ; non - HD : 27.5 % ) . -
pubmed
aureus (
MRSA ; 83.8 % )
infection accounting for
S. - pubmed
Conclusion : In
patients with similar
tumor burden , liver resection combined with intraoperative RFA for unresectable
CLM can achieve long - term outcomes similar to hepatectomy alone for resectable
CLM . -
pubmed
Hypokalemia was associated in six
patients . -
pubmed
Human papillomavirus (
HPV ) is the second most common cause of
cervical cancer worldwide . -
pubmed
The aim of this study was to determine the prevalence of
HPV and
HPV types in women with a
normal cytology of the cervix living in the upper and lower regions of Punjab , Pakistan , and to analyze the risk factors for
HPV in this region . -
pubmed
This study highlights the need to conduct robust epidemiological studies in the region and to develop regular
HPV screening so that the situation does not reach an alarming stage resulting in
cervical cancer . -
pubmed
MiRNAs found differentially expressed in symptomatic compared with presymptomatic mutation carriers were further evaluated in a cohort of 17
patients with
sporadic FTD , 13
patients with sporadic
Alzheimer ' s disease (
AD ) and 10 healthy controls ( HCs ) of similar age . -
pubmed
Aim : To evaluate the efficacy of antihistamines in reducing
pruritus in
psoriasis , 61
patients were randomized to be treated for 1 week with
clemastine ( n = 20 ) ,
levocetirizine ( n = 21 ) or placebo ( n = 20 ) . -
pubmed
Conclusions : Antihistamines of the first and second generations seem to be effective in reducing
itch in
patients with
psoriasis , albeit the antipruritic effect is rather moderate . -
pubmed
In the United States , the most common vectorborne pathogens are transmitted by ticks or mosquitoes , including those causing
Lyme disease ;
Rocky Mountain spotted fever ; and West Nile ,
dengue , and
Zika virus diseases . -
pubmed
Transmission in Puerto Rico , the U.S. Virgin Islands , and American Samoa accounted for most reports of
dengue , chikungunya , and
Zika virus diseases ;
West Nile virus was endemic , and periodically epidemic , in the continental United States . -
pubmed
BACKGROUND : We aim to investigate factors that may contribute to failure of eradication of
dysplastic Barrett ' s Esophagus among
patients undergoing radiofrequency ablation treatment . -
pubmed
RESULTS : A total of 107
patients underwent radiofrequency ablation for Barrett 's Esophagus , the majority white ,
overweight , and male . -
pubmed
Before treatment , 63
patients had low - grade dysplasia , and 44
patients had high - grade dysplasia or
carcinoma . -
pubmed
Complete eradication was achieved in a majority of
patients ( 57 % for
metaplasia , and 76.6 % for
dysplasia ) . -
pubmed
There is controversy regarding its use in younger
women because of their underrepresentation in trials and the concern for late
toxicity . -
pubmed
Objective : The aim of the present study was to assess the correlation between
patient history , physical examination , and electrophysiological method of assessment in
patients with clinical suspicion of
carpal tunnel syndrome (
CTS ) . -
pubmed
Patients and Methods : Results of electrophysiological examinations performed from 2009 to 2016 on 3151 hands of 2516
patients who had symptoms that clinically suggested
CTS were examined retrospectively . -
pubmed
Patients were assessed in terms of age , gender , direction of
nerve compression , and presence and degree of
CTS as determined electrophysiologically . -
pubmed
Objective : To analysis teratogenic effect of
GDC-0449 to fetus and set up the
animal model of
GDC-0449 induced
oromandibular limb hypogenesis in
mouse for further research of its pathogenesis . -
pubmed
Results : The
mice were exposed to
GDC-0449 on E11.5 and E12.5 had a high incidence of
cleft palate . -
pubmed
This work established a novel
mouse model for
oromandibular limb hypogenesis . -
pubmed
Patients with
RCC after kidney transplantation were matched in a 1:2 ratio with those without
RCC using the indication for transplantation , age at transplantation ( + - 10 years ) , recipient sex ( male / female ) , number of received transplants , living organ donor transplantation ( yes / no ) , and time of follow - up in days as matching criteria . -
pubmed
BACKGROUND :
Talazoparib ( 1 mg / day ) exhibited promising efficacy and safety in
patients with advanced
breast cancer during ABRAZO ( NCT02034916 ) ; this study evaluated
patient - reported outcomes ( PROs ) . -
pubmed
The axial effective stress and the radial displacement in the intervertebral disc , as well as the fluid loss in the nucleus pulposus , increased , whereas the pore pressure in the nucleus pulposus decreased with increased vibrational frequency under the same vibrational time , which may aggravate the
injury degree of
human lumbar spine . -
pubmed
Analgesic effects of the novel alpha2delta ligand
mirogabalin in a
rat model of
spinal cord injury . -
pubmed
In the present study , we investigated the analgesic effects of
mirogabalin in a
rat model of
spinal cord injury as an experimental
animal model for central
neuropathic pain . -
pubmed
The
spinal cord injury model was established by acute compression of the spinal cord at the T6/7 level with a microvascular clip in male
rats . -
pubmed
Twenty - eight days after
spinal cord injury , the
animals received the test compound orally , and the paw withdrawal threshold to mechanical stimulation was determined using the von Frey test at 0 ( before administration ) , 2 , 4 , 6 , 8 , and 24 h after administration . -
pubmed
In
rats subjected to
spinal cord injury , mechanical
allodynia was demonstrated by a decreased paw withdrawal threshold . -
pubmed
In conclusion ,
mirogabalin showed potent and long - lasting analgesic effects in a
rat model of
spinal cord injury and may therefore provide effective
pain relief for
patients with central
neuropathic pain . -
pubmed
In this article , we present a case of intravenous
BNC and concomitant oral
pregabalin misuse that developed in a monitored and treated
patient for the reason of
opioid dependence . -
pubmed
The objective of this study was to compare the transcriptome of
human palatal mucosa with
chronic oral stomatitis - associated Candida albicans infection to that of healthy oral mucosa . -
pubmed
CASE PRESENTATION : We report herein our experience with a case of
minor salivary gland sialolithiasis in a 67 - year - old
woman . -
pubmed
Normalized mean values for
patients with benign
cysts were 0.65 ( n=57 ) and malignant
cysts were 1.85 ( n=54 ) , demonstrating a significantly ( P<0.01 ) higher Hp in malignant samples . -
pubmed
Economic burden and treatment patterns for
patients with
diffuse large B - cell lymphoma and
follicular lymphoma in the USA . -
pubmed
PATIENTS : Consecutive
patients seen at a primary care institution 's Sports Concussion Clinic for sport - related
concussion that underwent diffusion tensor imaging . -
pubmed
RESULTS : Seventeen
concussion patients , ages 9 and 17 ( average = 12.5 years ; median = 13 years , 11 males and 6 females ) , were matched with age and gender controls who had an MRI following a complaint of
headache . -
pubmed
Glucocorticoid resistance of allogeneic T cells alters the gene expression profile in the inflamed small intestine of
mice suffering from
acute graft - versus - host disease . -
pubmed
The enrolled
children diagnosed with
ASD were examined by magnetic resonance imaging ( MRI ) and took genetic tests to rule out other neurological and
congenital diseases . -
pubmed
Patients with ruptured ACL grafts had more medial tibiofemoral compartment
OA than those with an intact ACL graft ( p = 0.0003 ) . -
pubmed
OA was asymmetric in
patients with ruptured
ACL grafts with more
OA in the medial than in the lateral tibiofemoral compartment ( p = 0.013 ) and the patellofemoral compartment ( p = 0.002 ) . -
pubmed
The distribution of
OA between compartments was similar in
patients with an intact ACL graft . -
pubmed
KT-1000 values of
anterior knee laxity were higher in
patients with ruptured compared to those with intact ACL grafts ( p = 0.012 ) . -
pubmed
Side - to - side comparisons of
anterior knee laxity showed higher KT-1000 values in
patients with ruptured ACL graft ( p = 0.0003 ) and similar results in those with intact graft ( p = 0.09 ) . -
pubmed
CONCLUSIONS : Median 31 ( range 28 - 33 ) years after ACL reconstruction , 50 % of the
patients showed an intact ACL graft and no side - to - side difference regarding
anterior knee laxity . -
pubmed
Patients with ruptured ACL grafts had more
OA of the medial tibiofemoral compartment than those with intact ACL grafts . -
pubmed
Chronic or recurrent forms of
somatization lead to heavy emotional and financial burden to the
patients and their families . -
pubmed
In this study , 18
SFD patients and 21 matched healthy controls were enrolled and underwent an
18F - FDG PET scan . -
pubmed
In addition , the Pearson coefficients between the neuropsychological scores and regional brain
18F - FDG uptake values were computed for
SFD patients . -
pubmed
CONCLUSIONS : In this national analysis , a VATS approach for lobectomy in
patients who received induction therapy for locally advanced
NSCLC was not associated with worse short - term or long - term outcomes when compared to an open approach . -
pubmed
OBJECTIVE : We analyzed the clinical characteristics of
patients with
isolated epiglottic collapse (
IEC ) who had an epiglottic anteroposterior ( AP ) collapse as the only cause of
snoring during drug - induced sleep endoscopy ( DISE ) . -
pubmed
CONCLUSION : The clinical characteristics of
IEC patients differed from the control group , and
IEC could not be identified during awake endoscopy . -
pubmed
Oxytocin induced
labor causes region and sex - specific transient oligodendrocyte cell
death in neonatal
mouse brain . -
pubmed
This may be an underlying mechanism explaining the
human epidemiological data suggesting an association between induced labor and
mental disorders . -
pubmed
Integration of oral targeted therapies ( OTTs ) in the management of
CLL has fundamentally altered
CLL treatment pathways and improved outcomes for
patients with CLL.We review the cost - effectiveness of OTTs in the treatment of
CLL . -
pubmed
Infectious diseases are an important cause of
human death . -
pubmed
The " transcriptome after
death " involves the study of mRNA transcripts occurring in
human tissues after
death ( thanatos , Greek for
death ) . -
pubmed
Cystic trophoblastic tumor is an uncommon lesion which is occasionally seen after chemotherapy in metastatic retroperitoneal lymph nodes in
patients with
testicular germ cell tumor . -
pubmed
Coronary spastic angina (
CSA ) in premenopausal
women is rare , but has also been suggested to be associated with
estrogen decline during the menstrual cycle . -
pubmed
In this report , we describe the case of a young premenopausal
patient with refractory
CSA . -
pubmed
After the start of this treatment , the
patient became completely free of
angina episodes . -
pubmed
Although there are a few reports of the efficacy of hormone replacement therapy in premenopausal
women with
CSA , this is the first report of the efficacy of this therapy in a
woman as young as 22 years old . -
pubmed
< Learning objective : There are a few reports of episodes of
CSA occurring in relation to the phase of the menstrual cycle in premenopausal
women . -
pubmed
Characterization of
relapse patterns in
patients with
acute lymphoblastic leukemia treated with
blinatumomab . -
pubmed
It is approved for the treatment of
patients with relapsed / refractory B - cell
acute lymphoblastic leukemia (
B - ALL ) and in
patients with
minimal residual disease after intensive induction chemotherapy . -
pubmed
METHODS : We reviewed
patients treated with
blinatumomab with relapsed , refractory or
minimal residual disease - positive
B - ALL from 1 December 2014 to 31 December 2018 at a single academic medical center . -
pubmed
Patient demographics , blast percentage prior to
blinatumomab initiation , prior lines of therapy ,
blinatumomab treatment duration , sites of
relapse , progression free survival , and overall survival were collected . -
pubmed
Four ( 20 % )
patients developed extramedullary
relapse following
blinatumomab . -
pubmed
Background : Median overall survival is 12 to 15 months in
patients with
metastatic adrenal cortical carcinoma (
ACC ) . -
pubmed
These treatments may be attractive to
ACC patients with limited other therapeutic options . -
pubmed
The study included
patients who underwent combined
FLACS and AK , with
corneal astigmatism ranging from 0.4 to 1.5 diopters ( D ) . -
pubmed
Findings : While symptom - triggered therapy through instruments such as the CIWA - Ar protocol has shown to lower total
benzodiazepine dosage and treatment duration in
patients in
alcohol withdrawal , over - reliance on such tools may also lead providers to overlook other causes of
delirium . -
pubmed
Two of them ,
HeLa and
MCF-7 , are
human carcinogenic cells from
cervical carcinoma and
human breast cancer , respectively . -
pubmed
BACKGROUND : Second primary
malignancy in
patients with
papillary thyroid carcinoma after Chernobyl accident is an emerging problem . -
pubmed
RESULTS : Secondary primary
cancer was detected in 1.8 % ( 119 of 6559 ) of the
patients with
papillary thyroid carcinoma . -
pubmed
CONCLUSION :
Patients with
papillary thyroid carcinoma after Chernobyl accident are at risk of secondary primary
malignancy . -
pubmed
Awareness and screening of
secondary cancer is needed for
patients with
papillary thyroid carcinoma after Chernobyl accident . -
pubmed
Patients and methods We studied five
patients with
pancreatic ductal adenocarcinoma (
PDAC ) and one with
chronic myelogenous leukemia (
CML ) , who suffered from
AOSPD . -
pubmed
Prompt diagnosis of
AOSPD could avoid shortening of survival of
patients with an already poor prognosis by
infection . -
pubmed
Impact of
hypertension on short- and long - term survival of
patients who underwent emergency surgery for
type A acute aortic dissection . -
pubmed
Background : To explore the clinical characteristics and prognosis of
patients with
hypertension underwent emergency surgery for
type A acute aortic dissection (
TA - AAD ) . -
pubmed
Methods : The present study enrolled 712 consecutive
patients diagnosed with
TA -
AAD and received aortic repair surgery at our hospital between January 2014 to December 2018 . -
pubmed
Patients were grouped by preexisting
hypertension history and matched with propensity scores matching method . -
pubmed
However , our data suggested that
hypertensive patients presented with less intra - operative aortic valve involvement . -
pubmed
Case report : A 41 - year - old
woman underwent ultrasound ( US ) at 16 weeks , which showed
oligohydramnios and
intrauterine growth restriction (
IUGR ) . -
pubmed
An in vivo experiment with an orthotopic
glioma mouse model confirmed the advantages of the proposed methods . -
pubmed
Administering
D - aldosterone , 7 microgram 100 g-1 , to
rats results in a marked rise in
ammonium excretion and
metabolic alkalosis . -
pubmed
Twenty - six
patients with
metastases from a
germinal cancer of the testis were treated with
Mithramycin . -
pubmed
In cultures of chick embryo fibroblasts infected with
Rous sarcoma virus , incubation for a 2 - day period with 1 to 3 mM concentrations of this inhibitor , as late as 4 days after
infection , irreversibly prevented subsequent formation of foci of transformed cells . -
pubmed
[
Autonomic insufficiency in dialysis
patients ] . -
pubmed
With the aim of determining the evolution of
hypertension associated with
PHPT , we analyzed a group of 56
patients followed for a mean of 60 months ( range 10 - 101 months ) after successful parathyroidectomy for
PHPT . -
pubmed
None of the
patients had
renal impairment . -
pubmed
Two
hypertensive patients died during the follow - up from complications related to their
hypertension . -
pubmed
Twelve ( 21.8 % )
patients were
hypertensive before parathyroid surgery ( systolic greater than 160 mmHg and/or diastolic greater than 90 mmHg ) . -
pubmed
Pre - operative
creatinine clearance was lower in the
hypertensive patients than in normotensive
patients ( 65.4 + /- 27.5 vs 86.7 + /- 26 ml / min , p = 0.002 ) . -
pubmed
During follow - up , none of the
patients with pre - operative
hypertension became normotensive , whereas 32 % of the
patients who were normotensive preoperatively developed clinical
hypertension . -
pubmed
The
patients that developed
hypertension after parathyroidectomy were followed for a longer period than the normotensive
patients ( 76 + /- 17 vs 53 + /- 10 months , p = 0.005 ) , had a lower postoperative
creatinine clearance ( 74 + /- 28 vs 90 + /- 25 mg / min , p = 0.07 ) , and
higher cholesterol levels ( 6.2 + /- 1.5 vs 5.5 + /- 0.9 mmol / L , p = 0.08). -
pubmed
This study analyzes variation in bone microstructure with respect to gender , age , and
body weight in growing
macaques to determine whether the pattern of osteonal remodelling in
macaques is like that in analogous bones of
humans . -
pubmed
These data show that variation in bone microstructure occurs independent of gender , age , and
body weight in
macaques . -
pubmed
Moreover , intracortical bone turnover in the
macaque femur is much slower than in
humans , making them poor models to study the effects of weightlessness , but good models to study low turnover
skeletal dysplasias . -
pubmed
Antibodies to shiga holotoxin and to two synthetic peptides of the B subunit in sera of
patients with
Shigella dysenteriae 1
dysentery . -
pubmed
Acute- and convalescent - phase sera from 18 Thai patients and convalescent - phase sera from two Israeli patients and one Bangladeshi patient with
Shigella dysenteriae 1 ( Shiga )
dysentery were tested by enzyme - linked immunosorbent assay to detect antibodies that bind
S. - pubmed
Paired sera from 24 Maryland adults with
Shigella flexneri 2a or
Shigella sonnei diarrhea served as negative controls . -
pubmed
METHODS : All
patients with a diagnosis of
subaortic stenosis and complete or partial AV canal defect who had one or more Doppler echocardiographic examinations were identified from a computer data bank . -
pubmed
RESULTS : Twenty - one
patients with both
subaortic stenosis and
AV canal defect were identified over a 13 - year period . -
pubmed
In six
patients , serial examinations demonstrated the de novo occurrence of
subaortic obstruction over a period of 10 to 87 months . -
pubmed
In five
patients , progression of known
subaortic stenosis was documented over a 10- to 59 - month period . -
pubmed
Surgical resection of
subaortic stenosis was performed in 16
patients ; the echocardiographic diagnosis was confirmed in 15 of the 16 . -
pubmed
Immune deposits in iris biopsy specimens from
patients with
Fuchs ' heterochromic iridocyclitis . -
pubmed
No specific immune deposits were observed in the irises of the
patients with
Fuchs ' heterochromic iridocyclitis . -
pubmed
Diatrizoic acid was found to be useful when applied by insufflation for demonstration of the nasopharynx , trachea and greater bronchi , especially in
patients with
airway stenosis and low pulmonary reserve . -
pubmed
We have performed simultaneous measurements of the DC - magnetoencephalogram ( DC - MEG ) and DC - electrocorticogram ( DC - ECoG ) in
rats ( n = 6 ) subjected to 90 s of reversible
anoxia . -
pubmed
Attempts to protect the ovary from the toxic effects of radiation and chemotherapy are relevant to the management of the young
patient with
cancer . -
pubmed
Comparative gait analysis of two
strains of
turkey ,
Meleagris gallopavo . -
pubmed
Economic requirements have encouraged farmers to select broad - breasted
strains of
turkeys (
Meleagris gallopavo ) . -
pubmed
We report seven cases of
BaCO3 poisoning in one family ; three hospitalized
patients displayed classic signs of
barium toxicity , and one patient also developed
rhabdomyolysis ,
respiratory failure , and
hypophosphatemia . -
pubmed
Complications consisted of 17 local
haematomas ( 3 % ) and reversible
spasm at the puncture site in one
patient ( 0.2 % ) . -
pubmed
[ Effect of sclerotherapy in
patients with
bleeding due to
portal hypertension ] . -
pubmed
The author reports the preliminary results of an unrandomized trial comparing the effect of endoscopic
variceal sclerosis , shunt surgery and medical therapy in the management of
cirrhotic patients with
variceal bleeding , sixty - six
patients were studied , among them 23 received
sclerosis , 25 shunt surgery and 18 medical therapy . -
pubmed
A surgical case of
lipoma in the cerebellopontine angle in a 37 - year - old
man is reported . -
pubmed
The
patient 's chief complaints were
left hearing disturbance and
dizzy spells . -
pubmed
To prospectively assess the value of an algorithm in differentiating spontaneous from secondary
bacterial peritonitis , we performed serial paracenteses in 43 episodes of
ascitic fluid infection ( 28 spontaneous and 15 secondary ) in 40
patients . -
pubmed
After 48 h of treatment the concentration of ascitic fluid neutrophils was below the baseline pretreatment value in all episodes of spontaneous
peritonitis but in only two thirds of the
patients with secondary
peritonitis . -
pubmed
The optimal time for repeat paracentesis in
patients with infected
ascites appears to be 48 h after initiation of treatment . -
pubmed
We diagnosed nine
renal contusions , five subcapsular
hematomas ,
laceration with perirenal
hematoma in three cases and we detected extravasation of the contrast in five
patients . -
pubmed
The study was performed on endoscopic gastric biopsies of the oxyntic mucosa from 49
patients subdivided into the following groups : A ) with histologically normal mucosa and
normogastrinemia ( 22 cases ) , B ) with
atrophic gastritis and
normogastrinemia ( 12 cases ) , C ) with normal mucosa and
hypergastrinemia (
Zollinger - Ellison syndrome , retained antrum ) ( 7 cases ) and D ) with
atrophic gastritis and
hypergastrinemia ( with or without
pernicious anemia ) ( 8 cases ) . -
pubmed
Adjuvant
arthritis in
rats is a T - cell dependent "
autoimmune " disease with close similarities to several forms of
human arthritis . -
pubmed
Doxorubicin was further observed in
animal models of
subconjunctival scars caused by imbedded silk thread for its inhibitory action in vivo . -
pubmed
DESIGN : Blind analysis of serum samples , retrospective analysis of clinical data on
patients , and prospective follow - up of a subgroup of
patients with
Wegener granulomatosis . -
pubmed
PATIENTS : The study included 277
patients with
Wegener granulomatosis ( 222 with biopsy - proven disease ) and 1657 control
patients . -
pubmed
Prospective follow - up was on 172
patients with
Wegener granulomatosis . -
pubmed
A comparative study of portal hemodynamics was made in 79 cirrhotics ( 24 cirrhotics with a large spleen greater than or equal to 500 cm3 in volume , 55 cirrhotics with a spleen less than 500 cm3 in volume ) , 22
patients with
idiopathic portal hypertension , and 63 healthy adults who served as the control for portal and splenic venous flows . -
pubmed
A total of 168 chronic dialysed
patients were subjected to echography ; 48 % of them presented aneurysmal alterations of the
fistula , with a tendency to increase in proportion to the length of the dialysis period . -
pubmed
We report a case of
nasolacrimal duct obstruction with histopathology compatible with
localized sarcoidosis , in a
patient with no evidence of
systemic disease . -
pubmed
Twenty five healthy
people and 25
patients with
shoulder pain underwent US control over a 12 - month period : 24
patients with
shoulder pain had
rotator cuff and / or biceps tendon lesions . -
pubmed
[ Effect of combination chemotherapy with
adriamycin in elderly
non - Hodgkin ' s lymphoma patients ] . -
pubmed
The effects of several new specific bradycardic agents , AQ - A39 and
AQ - AH 208 , were evaluated in two models of
myocardial ischaemia in anesthetized
dogs . -
pubmed
In the first model , equal bradycardic doses of
AQ - AH 208 and
propranolol were compared for their effects on coronary collateral blood flow in
dogs subjected to an acute
coronary artery occlusion . -
pubmed
Specific humoral substances produced and secreted by
human tumors that cause
hypercalcemia have not been identified . -
pubmed
Looking for frequency of
somnambulism in 3 homogeneous groups of children , a first group of
migrainous children , a second group of
epileptic children and a third group of normal children , the authors have observed that an antecedent of
somnambulism existed in 28 % of
migrainous children , when it was found in only 6 % of
epileptic children , and in 5 % of normal children . -
pubmed
The practical interest to know this association is that
somnambulism may be a real clinical marker of
migrainous background that should be searched for in every
patient presenting with
chronic cephalalgia . -
pubmed
It is recommended that such data be determined for each type of laser prior to attempting short - pulsed laser internal trabeculotomy in
patients with
glaucoma . -
pubmed
In the fungus
Achlya ambisexualis sexual development in the male
strain E87 is controlled by the
steroid hormone
antheridiol . -
pubmed
[ Incidence of
mycotic infections in
patients with
acute myeloid leukemia . -
pubmed
The highest levels were recorded in active
acromegalics , but cured
patients also had higher levels than the control group . -
pubmed
Urines of
osteoarthrotic patients were compared with those of healthy
persons and rheumatoid
patients . -
pubmed
The profile of urinary peptides of
patients with mild form of
osteoarthrosis differed significantly from that of other groups studied . -
pubmed
The results of
patients with
rheumatoid arthritis were similar to those of
patients with activated or severe form of
osteoarthrosis . -
pubmed
The beneficial effect of
loperamide in some
children with severe protracted
diarrhoea which persisted when nil by mouth , made us suspect that
loperamide may have an antisecretory action . -
pubmed
Six of 32
patients with a preoperative
neurologic deficit demonstrated mild but definite postoperative neurologic improvement . -
pubmed
Evidence is presented that
hypoperfusion produced by occlusion of major cranial vessels plays an important role in temporary and permanent
neurological deficits seen in
patients with
cerebrovascular disease . -
pubmed
Iodine-123 thyroid scintigraphy allows the diagnosis of a functioning
retrosternal goiter in a
patient with a mediastinal mass . -
pubmed
carried out with the aim of surveying 44
patients who had malignant
tumours of the ovaries : - one third of the cases had a positive level more than 10 ng per ml ; - the presence and the serial level depend more on the histological nature of the
tumour than the stage of its evolution ; - when a serial level has been negative before treatment it has never become positive in in a definite and continuous manner when the
tumour progresses . -
pubmed
The diagnostic value of Doppler ultrasound evaluation of
peripheral vascular disease in
diabetic patients is discussed . -
pubmed
False diagnosis of
myocardial infarction due to an extreme left sided
cardiac rotation in two
patients . -
pubmed
We present two
patients with an extremely rare condition :
abnormal cardiac levoposition . -
pubmed
Long - lasting
hypergastrinaemia has been demonstrated to elicit ECL cell proliferation in laboratory
animals , inducing
ECL cell hyperplasia ,
dysplasia and
ECL cell tumours , i.e. -
pubmed
However , in experimental
rodents it is believed that
hypergastrinaemia is not per se a stimulus capable of inducing ECL cell transformation , a predisposing genetic background being required for
tumour development in endocrine organs . -
pubmed
In
man , long - standing
hypergastrinaemia exerts the same proliferative pressure on ECL cells and is associated with
hyperplasia with or without dysplastic changes and
carcinoid development . -
pubmed
For this reason
human gastric argyrophilic ECL
carcinoids are subdivided into three main groups depending on their clinical background : ( 1 ) gastric
carcinoids in
patients with
chronic atrophic gastritis ; ( 2 )
gastric carcinoids in patients with
Zollinger - Ellison and multiple endocrine neoplasia type 1 syndrome (
MEN - ZES ) ; and ( 3 ) solitary , sporadic
gastric carcinoids . -
pubmed
METHODS : Thirty - six
HIV - infected patients were enrolled in the study . -
pubmed
All
patients completed an
allergy questionnaire and physical examination . -
pubmed
OBJECTIVE : To determine how multiple risk factors for
osteoporotic fractures could be modified by high - intensity strength training exercises in postmenopausal
women . -
pubmed
The study was undertaken to examine 34 male
patients with
unstable angina pectoris who underwent coronary angiography ( in the period of instability and at rehospitalization ) and study of protein and lipid parameters in their plasma . -
pubmed
Analbuminemia does not significantly influence hepatocarcinogenesis on comparing
F344 rats and a congenic line carrying the analbuminemic mutation . -
pubmed
Analbuminemic rats differ from
Sprague - Dawley rats ( SD ) , their
strain of origin , with respect to carcinogenic susceptibility of various organs . -
pubmed
Repeated intradermal injection of inactivated
BHV-1 antigen elicited neither the virus neutralizing antibody nor positive
skin reaction in
cattle free from
BHV-1 infection . -
pubmed
Cattle initially positive by VN and intradermal tests showed steady increase in antibody titre , and some of them developed little or no
skin reaction following repeated DTH testing . -
pubmed
We have conducted a Phase I trial to determine the maximum tolerated dose of
CPT-11 together with a fixed dose of
cisplatin in
patients with advanced
lung cancer , and the dose - limiting
toxicities of this combination . -
pubmed
All three
patients ( all four cycles ) given 90 mg m-2 of
CPT-11 experienced grade 3
diarrhea . -
pubmed
K - wire fixation of
supracondylar humeral fractures in
children : results of open reduction via a ventral approach in comparison with closed treatment . -
pubmed
The morbidity and functional outcome of K - wire fixation of dislocated
supracondylar humeral fractures in
children after open reduction through a ventral approach were studied , using the results after closed reduction as a golden standard . -
pubmed
Only one out of 11
patients showed mild
varus deformity after open reduction , while this slight malalignment occurred in five of 35
patients after closed reduction . -
pubmed
It can be concluded that K - wire fixation of dislocated
supracondylar fractures in
children gives excellent results and that open reduction via a ventral approach is a logical , safe and elegant alternative , if closed reduction fails . -
pubmed
Coagulopathy and fibrinolysis following the
bite of a
hump - nosed viper (
Hypnale hypnale ) . -
pubmed
Fluconazole therapy of
oropharyngeal candidiasis in a
patient with
multiple endocrine failure does not correlate with
Candida albicans susceptibility to
fluconazole in vitro . -
pubmed
We report a case of
oropharyngeal and oesophageal candidiasis in a 23 - year - old
man with
endocrinopathy syndrome . -
pubmed
The
patient was maintained on
fluconazole 200 mg daily without
relapse . -
pubmed
We conclude that
fluconazole 400 mg daily is effective against
oropharyngeal and oesophageal candidiasis in a
patient with
endocrinopathy syndrome , despite the infecting
Candida albicans strains being resistant to
azole antifungals in vitro . -
pubmed
In hippocampal neurons cultured from
trisomy 16 ( Ts16 )
mice ( a model for
Down ' s syndrome ) , the maximum inward conductance mediated by these channels was reduced 47 % relative to control diploid neurons . -
pubmed
Effects of novel and conventional anti -
cancer agents on
human endothelial permeability : influence of
tumour secreted factors . -
pubmed
Monolayers of
human umbilical vein endothelial cells (
HUVEC ) grown on membrane filters were incubated in drug in normal growth medium or medium conditioned by the
human melanoma cell line ,
RPMI-7951 ( TCM ) . -
pubmed
The effect of chronic
periodontal disease on
human jaw muscles : a pilot study using computed tomography . -
pubmed
Patients with chronic
periodontal disease sometimes complain of difficulty in masticating hard foods . -
pubmed
Mutants of
Escherichia coli heat - labile enterotoxin as an adjuvant for nasal
influenza vaccine . -
pubmed
When
influenza vaccine was administered intranasally with LT7 K and
LT192 G , BALB / c
mice developed high levels of serum and local antibodies to the HA molecules . -
pubmed
Subcutaneous nodules caused by
Pseudomonas aeruginosa without
sepsis . -
pubmed
Suppurative panniculitis can also be caused by
P. - pubmed
METHODS : In our study we included 45 healthy , non pregnant , female controls , 45 healthy pregnant
women , and 45
preeclamptic women . -
pubmed
Expression of the beta1 subunit by renal glomerular cells was evaluated by biochemical and morphological means in short- and long - term
diabetic rats . -
pubmed
Western blots of isolated
rat renal glomeruli demonstrated that the expression of beta1 increases along with age as well as with the
hyperglycaemic state . -
pubmed
The methods are illustrated with a dataset consisting of
stroke rehabilitation
inpatients discharged during a 3 - year period with an admission date that is within 1 year after
stroke . -
pubmed
As yet , there is no consistently effective method to predict an individual
ITP patient 's response to splenectomy . -
pubmed
Despite
pneumococcal vaccination prior to splenectomy , fatal
fulminant sepsis is an omnipresent possibility . -
pubmed
METHODS : A retrospective review of 55
women with early - stage
breast cancer treated from 1990 to 1995 was performed . -
pubmed
PURPOSE : To evaluate intraocular pressure ( IOP ) control after extracapsular
cataract extraction ( ECCE ) with posterior chamber intraocular lens ( PCIOL ) implantation in
patients with
capsular glaucoma (
CG ) and coexisting
cataract . -
pubmed
METHODS : This prospective study included 20
patients ( 20 eyes ) having
CG and
cataract whose IOPs were under 22 mm Hg and controlled with antiglaucoma medication . -
pubmed
CONCLUSION : The result of our study revealed that ECCE with PCIOL implantation may be a reliable choice in controlling IOP in
patients with
CG . -
pubmed
A total of 17
patients ( 18 feet ) were evaluated following external neurolysis for heel
pain caused by entrapment of the first branch of the lateral plantar nerve . -
pubmed
[
Listeriosis : an infrequent
infection in patients with
HIV ] . -
pubmed
The
patient dead 72 hours later with
hepatic encepholopathy . -
pubmed
Listeriosis is an infrequent disease in patients with
HIV that causes difficult diagnostic problems , principally in patients without prophylaxis with
cotrimoxazole for
PCP . -
pubmed
A case of
PCL in a 72 - year - old
man with moderate
aortic stenosis is presented . -
pubmed
The
patient was investigated because of
pericardial effusion and diagnosis of
diffuse large B - cell lymphoma was obtained by open - chest biopsy of the heart . -
pubmed
Accelerated recovery after endotoxic challenge in heat
shock - pretreated
mice . -
pubmed
These observations suggest that the mechanism of heat
shock - mediated protection ( stress tolerance ) after LPS challenge is due to an increase in the capacity of the
organism to recover rather than deterrence from the insult . -
pubmed
Acute
toxicity of drainage ditch water from a Washington State
cranberry - growing region to
Daphnia pulex in laboratory bioassays . -
pubmed
To determine the toxic effects of multiple pesticides entering the GDD , standardized laboratory
toxicity tests with
D. - pubmed
Immunomodulatory activity of the aqueous extract from rhizome of
Smilax glabra in the later phase of adjuvant - induced
arthritis in
rats . -
pubmed
Our previous paper has reported that the aqueous extract from
Rhizoma Smilacis Glabrae ( RSG ) remarkably inhibited the primary
inflammation of adjuvant
arthritis (
AA ) in
rats . -
pubmed
METHOD : One hundred and sixty - seven
adults suffering from
anxiety and/or
depression and not receiving any form of psychological treatment or counselling were randomly allocated to receive , with or without medication , BtB or treatment as usual ( TAU ) . -
pubmed
RESULTS :
Patients who received BtB showed significantly greater improvement in
depression and
anxiety compared to TAU by the end of treatment ( 2 months ) and to 6 months follow - up . -
pubmed
Successful pregnancy outcome in a
patient with complete
heart block . -
pubmed
The classification and diagnosis of
human tumors by tissue culture methods . -
pubmed
In a prospective study , we analysed 117
patients ( age 17 - 79 years ) who were treated with IVIG for various
neurological diseases including
chronic inflammatory demyelinating polyneuropathy ,
diabetic amyotrophy ,
inclusion body myositis ,
multiple sclerosis ,
Guillain - Barre syndrome ,
Miller - Fisher syndrome ,
multifocal motor neuropathy ,
myasthenia gravis and
polymyositis . -
pubmed
Rash or mild
headache occurred in 8
patients , especially when IVIG was given with infusion flow higher than 10 g / h. Two
patients showed a severe complication with
deep vein thrombosis . -
pubmed
Patients with pre - existent disorders like
heart or renal insufficiency or immobilised
patients , however , may be at higher risk for complications . -
pubmed
The effects of
growth hormone deficiency and replacement on glucocorticoid exposure in
hypopituitary patients on
cortisone acetate and
hydrocortisone replacement . -
pubmed
CONCLUSIONS : Our data suggest that tissue exposure to
glucocorticoid is supra - physiological in
hypopituitary patients with untreated
GH deficiency taking
hydrocortisone replacement therapy . -
pubmed
We report a case of proliferative
myositis in the right biceps of a 56 - year - old
man with
acquired immune deficiency syndrome (
AIDS ) . -
pubmed
We conducted a study to evaluate pharyngeal and palatal functions following reconstruction of soft - palate defects with radial forearm free flaps in 16
patients who had undergone resection of the soft palate for
squamous cell carcinoma . -
pubmed
Nine
patients had partial
soft - palate defects and 7 had total defects . -
pubmed
In addition , 14
patients had
defects of the base of the tongue . -
pubmed
One
patient developed a transient
salivary fistula , which resolved with conservative management . -
pubmed
Four
patients without
dysphagia resumed oral intake 2 weeks after surgery . -
pubmed
The 12
patients with
dysphagia underwent swallowing therapy . -
pubmed
Speech was
hypernasal in 2
patients and hyponasal in 3 . -
pubmed
Protection against
murine endotoxemia by treatment with
Ruta chalepensis L. , a plant with anti - inflammatory properties . -
pubmed
The anti - inflammatory effect of the extract of
Ruta Chalepensis L. (
Rutaceae ) on the course of lethal
endotoxemia in BALB / c
mice was studied . -
pubmed
Pioglitazone prevents
hepatic steatosis ,
fibrosis , and enzyme - altered lesions in
rat liver cirrhosis induced by a
choline - deficient
L - amino acid - defined diet . -
pubmed
Non - alcoholic steatohepatitis (
NASH ) may progress to
liver cirrhosis , and
NASH patients with
liver cirrhosis have a risk of development of
hepatocellular carcinoma . -
pubmed
These results indicate that
pioglitazone may be one of the candidates for the benefit drugs for the
liver disease of
patients with
NASH . -
pubmed
However ,
ventricular tachycardias (
VT ) still pose a major problem in a number of cardiac
patients . -
pubmed
The majority of
ventricular arrhythmias , however , are substrate - related reentry
tachycardias , most commonly based on an
infarct scar Therapy of first choice for these
patients is the treatment with an implantable Cardioverter / Defibrillator ( ICD ) . -
pubmed
Characterization of a
mouse recombination hot
spot locus encoding a novel non - protein - coding RNA . -
pubmed
Our current knowledge of recombination hot
spot activity in
mammalian systems implicates a role for both the primary DNA sequence and the nature of the chromatin domain around it . -
pubmed
We present a high resolution analysis of a new recombination hot
spot in the
mouse genome which maps to
mouse chromosome 8 C - D. Haplotype diversity analysis across 40 different
strains of
mice has enabled us to map recombination breakpoints to a 1 - kb interval . -
pubmed
It is clear that the development of a safe and effective vaccine for
human immunodeficiency virus type 1 (
HIV-1 ) remains a crucial goal for controlling the
acquired immunodeficiency syndrome epidemic . -
pubmed
Body weight , tail width and food intake , were measured daily and physical activity was measured hourly in normal lean
S. - pubmed
The Relationship between
chlamydia trachomatis and
chlamydia pneumoniae as the cause of
neonatal conjunctivitis (
ophthalmia neonatorum ) . -
pubmed
Chlamydia trachomatis was confirmed in 20 ( 15.3 % ) using ligase chain reaction and
C. - pubmed
This prospective study included 21
patients with N0 or N1
squamous - cell carcinoma of the oral cavity and the oropharynx . -
pubmed
The sentinel lymph node was not identified in one
patient with
recurrence T2N0M0
squamous - cell carcinoma of the oropharynx radiated 3 years earlier . -
pubmed
The specificity of the method was 100 % , as was the positive predictive value , because no sentinel node was diagnosed positive wrongly on frozen sections among
patients without true histological node
metastasis . -
pubmed
DISCUSSION : For routine care of
patients with
squamous - cell carcinoma of the oral cavity and the oropharynx detection of the sentinel lymph node is proposed primarily for
patients with T1T2N0 staging . -
pubmed
HIV co - infection is associated with reduced
HCV treatment response rates and accelerated
HCV - related liver disease . -
pubmed
Detection of positive - strand
HCV RNA was 100 % in both groups ; negative - strand
HCV RNA was detected in four ( 33 % )
HCV mono - infected persons and in nine ( 64 % )
HCV / HIV co - infected persons . -
pubmed
Esophageal perforation in a
patient with metastatic
breast cancer to esophagus . -
pubmed
We present the case of a
patient with
esophageal perforation due to dilatation treatments for
dysphagia secondary to a
distal stricture , later proven to be caused by esophageal
metastasis from a
breast cancer treated 19 years earlier . -
pubmed
MATERIAL AND METHODS : The study group consisted of 438
patients , aged 21 - 46 ( average 29.7 ) , treated because of primary or secondary
infertility between January 1999 and March 2003 at Gynecological Endocrinology Department of Medical University of Warsaw . -
pubmed
Some species of Babesia cause bovine
babesiosis infecting erythrocytes of the
cattle and wild ruminants , and undergo a complex developmental cycle in ticks which serve as biological vectors . -
pubmed
cause
bovine theileriosis infecting lymphocytes as well as erythrocytes of the
cattle and wild ruminants , and similar to Babesia undergo a complex developmental cycle in ticks . -
pubmed
Today the implantable cardioverter - defibrillator ( ICD ) has become a commonplace therapy around the world for
patients with both ischemic and non - ischemic
cardiomyopathy and an ejection fraction ( EF ) & lt ; or = 35 % . -
pubmed
Can fleas from
dogs infected with canine
visceral leishmaniasis transfer the
infection to other mammals ? -
pubmed
In order to investigate the possible role of
dog fleas in the transmission of trypanosomatids , ectoparasites were removed from 59
dogs testing positive for canine zoonotic
visceral leishmaniasis according to the indirect fluorescent antibody test ( IFAT ) . -
pubmed
Sixteen
hamsters tested positive for
Leishmania infection , 14 on the basis of PCR amplification and four by IFAT assay ( two animals testing positive in both assays ) . -
pubmed
chagasi by fleas can not be proven unambiguously even though the
hamsters developed
infection . -
pubmed
In 42
alcoholic inpatients we performed an open randomized study to compare the effects of
diazepam and
gamma - hydroxybutyrate (
GHB ) on the suppression of severe
alcohol withdrawal syndrome and
hypercortisolism . -
pubmed
[ Changes of toxins and inflammatory mediators in serum after plasma exchange in
patients with severe
hepatic disease ] . -
pubmed
The largest increase ( approximately 318 % ) was attained in
mice bearing EAT
ascites and receiving 12.5 mg / kg of bromelain . -
pubmed
Osteomalacia in a
patient with
primary intestinal lymphangiectasis (
Waldmann ' s disease ) . -
pubmed
We report a case of
osteomalacia in a 63 - year - old
patient with delayed - onset of
PIL , for which she was on dietary treatment . -
pubmed
OBJECTIVES : To determine the effectiveness and safety of arthrographic distension of the glenohumeral joint in the treatment of
adults with
adhesive capsulitis . -
pubmed
Safety and efficacy of
bivalirudin monotherapy in
patients with
diabetes mellitus and
acute coronary syndromes : a report from the ACUITY ( Acute Catheterization and Urgent Intervention Triage Strategy ) trial . -
pubmed
OBJECTIVES : We sought to evaluate clinical outcomes of
patients with
diabetes mellitus in the ACUITY ( Acute Catheterization and Urgent Intervention Triage Strategy ) trial , overall and by treatment arm . -
pubmed
Whether these results apply to
patients with
diabetes is unknown . -
pubmed
RESULTS :
Diabetes was present in 3,852 randomized
patients ( 27.9 % ) . -
pubmed
Compared with nondiabetic
patients ,
diabetic patients had higher 30 - day rates of net adverse clinical outcomes ( 12.9 % vs. 10.6 % ; p & lt ; 0.001 ) , composite
ischemia ( 8.7 % vs. 7.2 % ; p = 0.003 ) , and
major bleeding ( 5.7 % vs. 4.2 % ; p & lt ; 0.001 ) . -
pubmed
CONCLUSIONS : Diabetic
patients with
ACS managed invasively have higher rates of composite
ischemia and major
bleeding . -
pubmed
Patients with obstetric
lacerations were randomized to repair with either blunt or sharp needles . -
pubmed
Immunogenicity and reactogenicity of two
diphtheria -
tetanus - acellular
pertussis -
hepatitis B - inactivated
polio virus -
Haemophilus influenzae type b vaccines administered at 3 , 5 and 11 - 12 months of age . -
pubmed
The aim of this study was to evaluate the immunogenicity and reactogenicity of two commercial
diphtheria - tetanus- acellular pertussis -
hepatitis b - inactivated polio virus -
Haemophilus influenzae type b ( DTaP -
HBV - IPV / Hib ) combination vaccines when administered to infants at 3 , 5 and 11 - 12 months of age . -
pubmed
Proteomic analysis of alterations in the secretome of
Arabidopsis thaliana suspension cells subjected to
nutritional phosphate deficiency . -
pubmed
The results indicate that transcriptional control is but one of many factors contributing to
Arabidopsis Pi
starvation responses , and highlight the importance of parallel biochemical / proteomic studies of -Pi plants . -
pubmed
The protective role of
alpha - Toc as an antioxidant was evident and it could be used in the treatment of
equine ocular diseases in which free radicals are involved . -
pubmed
It seems of utmost importance for every physician treating
hypertensive patients to become familiar with
sexual dysfunction ( through better education and specific seminars ) for the proper management of these
patients . -
pubmed
METHODS : Data collected from
subjects enrolled in the
Atropine in the Treatment of
Myopia ( ATOM ) study were analysed . -
pubmed
Early detection and prevention of
CRPCa may provide a new strategy to improve survival of
patients diagnosed with
PCa at risk to fail standard
androgen deprivation therapy ( ADT ) . -
pubmed
Pathogenetic factors responsible for the development of the
CRPCa phenotype are detectable in the
patient 's
PCa tissue long before the clinical onset of the disease . -
pubmed
Neurodegeneration and prolonged immediate early gene expression throughout cortical areas of the
rat brain following acute administration of
dizocilpine . -
pubmed
Here , we describe the clinical features of a
patient who suffered
cystic maculopathy during
paclitaxel therapy . -
pubmed
CASE : A 62 - year - old
woman complained of
visual disturbances in both eyes after receiving
paclitaxel treatment of six months for metastatic
breast cancer . -
pubmed
CONCLUSION :
Paclitaxel treated
patients should be followed carefully for ophthalmic complications , especially
cystic maculopathy . -
pubmed
BACKGROUND : Extensive studies in
rodents have identified olfactory ensheathing cells ( OECs ) as promising candidates for cell - based therapies of
spinal cord and peripheral nerve injury . -
pubmed
During 18 months of follow - up , the primary end point ( composite of all - cause mortality and
HF readmission ) occurred in 39 % of the nondepressed
patients and 42 % of depressed
patients . -
pubmed
The effect of the
DMP was significantly different in nondepressed than in depressed
HF patients . -
pubmed
In
patients without
depressive symptoms ,
DMP resulted in a trend for lower incidence of the primary end point ( hazard ratio : 0.8 , 95 % confidence interval : 0.61 to 1.04 ) , whereas the reverse was observed in patients with
depressive symptoms ( hazard ratio : 1.3 , 95 % confidence interval : 0.95 to 1.98 ) . -
pubmed
Prognostic value of initial echocardiographic features in
patients with
tuberculous pericarditis . -
pubmed
We sought to determine initial prognostic factors in
patients with
TB pericarditis . -
pubmed
SUBJECTS AND METHODS : We evaluated initial presentation and clinical outcomes ( mean follow - up 32 + -27 months ) in 60 consecutive
patients newly diagnosed with
TB pericarditis . -
pubmed
RESULTS : Initial presentations were
pericardial effusion (
PE ) , effusive - constrictive
pericarditis , and
constrictive pericarditis in 45 ( 75 % ) , 9 ( 15 % ) , and 6 ( 10 % )
patients , respectively . -
pubmed
Of the 54
patients without initial constrictive
pericarditis , 32 ( 59 % ) showed echogenic materials in
PE , including frond - like exudative coating and fibrinous strands . -
pubmed
All
patients with effusive - constrictive
pericarditis showed echogenic
PE . -
pubmed
CONCLUSION : Initial pericardial constriction and echogenic
PE are poor prognostic signs for persistent
pericardial constriction and pericardiectomy in
patients with newly diagnosed
TB pericarditis . -
pubmed
Here we combined MTI with VBM analysis to evaluate
extratemporal damage in
patients with
TLE . -
pubmed
MATERIALS AND METHODS : We studied 23 healthy controls and 21
patients with
TLE with mean ages , respectively , of 37.6 + - 10.9 and 38.6 + - 9.02 years . -
pubmed
Induction of
osteoarthritis and
metabolic inflammation by a very high - fat diet in
mice : effects of short - term exercise . -
pubmed
Wheel - running exercise reduced progression of
OA in the medial femur of
obese mice . -
pubmed
CONCLUSION :
Obesity induced by a very high - fat diet in
mice causes
OA and systemic
inflammation in proportion to body fat . -
pubmed
Mitochondria have been implicated in several
human diseases , including
cardiac dysfunction , and play a role in the aging process . -
pubmed
BACKGROUND : In
patients with acute
ST - segment elevation myocardial infarction (
STEMI ) , recent clinical guidelines recommend that primary percutaneous coronary intervention ( PCI ) should be performed within 90min of first medical contact or 45min after admission in cathlab . -
pubmed
METHODS : From January 2007 to March 2008 , 177
patients were admitted within 12hours of a
STEMI in our institution , and 87 were referred for a direct coronary angiography for primary PCI ( 47 by mobile medical emergency unit , 40 by the emergency department of the institution ) . -
pubmed
BACKGROUND :
Helicobacter pylori are a persistent colonizer of the
human gastric mucosa , which can lead to the development of
peptic ulcer disease and
gastric adenocarcinomas . -
pubmed
We describe to our knowledge the sixth case of a
papillary thyroid carcinoma within an
amyloid goiter , arising in a 45 - year old
woman with
chronic renal failure due to primary
amyloidosis . -
pubmed
The
patient suffered a total thyroidectomy with the histological diagnosis of
amyloid goiter with a multifocal
papillary carcinoma of follicular variant . -
pubmed
Two years and a half after the surgery the
patient is free of
recurrence . -
pubmed
OBJECTIVE : To evaluate the use of reproductive health care and incidence of paediatric
HIV infection during the expansion of antiretroviral therapy and services for the prevention of mother - to - child transmission in rural Malawi , and the influence of integration of these
HIV - related services into general health services . -
pubmed
Isotopic steady state was achieved within 24 - 48 h.
Creatine pool size calculated from urinary
D ( 3 )- creatinine enrichment at 72 h significantly increased with muscle accrual in
rat growth , significantly decreased with
dexamethasone - induced skeletal
muscle atrophy , was correlated with lean body mass ( r = 0.9590 ; P & lt ; 0.0001 ) , and corresponded to predicted total muscle mass . -
pubmed
PARTICIPANTS :
Patients with
diabetes aged 18 years or more from the Royal Victorian Eye and Ear Hospital , Victoria , Australia . -
pubmed
Korean red ginseng improves blood pressure stability in
patients with intradialytic
hypotension . -
pubmed
According to prehemodialysis blood pressure ( BP ) , 38
patients with
IDH were divided into group A ( BP & gt;= 140/90 mmHg , n = 18 ) and group B ( BP & lt ; 140/90 mmHg , n = 20 ) . -
pubmed
Chewing KRG renders
IDH patients better resistance to acute BP reduction during hemodialysis via activation of vasoconstrictors . -
pubmed
This case report describes a diagnosis of right - sided isomerism and specifically right - sided
bronchial isomerism in a
patient who was being investigated for deteriorating
bronchiectasis . -
pubmed
Ivemark syndrome ( also known as
right atrial isomerism ) combines these associations with
malrotation of the gut and a midline liver.2 Interestingly , left - sided isomerism is associated with
polysplenia as well as midline liver ,
malrotation of the gut , partially anomalous pulmonary venous drainage and
cardiac septal defects.3 To the best of our knowledge cases of right - sided isomerism are sufficiently rare in adulthood that there are only two other reports in the literature and only one of the
patients had
bronchial isomerism.4,5 . -
pubmed
Experimental adaptation of an
influenza H5 HA confers respiratory droplet transmission to a reassortant
H5 HA / H1N1 virus in ferrets . -
pubmed
Our findings emphasize the need to prepare for potential pandemics caused by
influenza viruses possessing H5 HA , and will help individuals conducting surveillance in regions with circulating
H5N1 viruses to recognize key residues that predict the pandemic potential of isolates , which will inform the development , production and distribution of effective countermeasures . -
pubmed
A split - root system was applied to analyse the systemic and local response of
Arabidopsis thaliana to
sulfur starvation . -
pubmed
From each of 30
pigs with an
infection of
L. - pubmed
After 14- day simulated weightlessness for
rats , their food - intake and
body weight increase were less than those in the control group . -
pubmed
A 45 - year - old
man who underwent
cataract surgery 2 years previously presented with
decreased vision in his left eye . -
pubmed
Despite this viral escape mechanism , the innate immune system strongly reacts to
HCV within the first days after
infection . -
pubmed
In this review , the available information on how polymorphisms in
T2DM - associated genes / loci do directly affect the properties of
human islet cells are presented and discussed , including some clinical implications and the role of epigenetic mechanisms . -
pubmed
Five species of
malaria mosquitoes :
An . - pubmed
Among the North Tajikistan
malaria mosquitoes ,
An . - pubmed
Several species of the Lactobacillus genus that are frequently used as probiotics for
human consumption merit particular attention because they are increased in the gut microbiota under high - fat diets , are more abundant in
obese humans , and are selected by growth - promoter antibiotics ; moreover , the administration of these bacteria in experimental models is linked to the development of
obesity . -
pubmed
OBJECTIVE : The purpose of this pilot study was to evaluate the effects of extracorporeal
shock wave therapy on healing of subcondylar
mandibular fracture in
rats . -
pubmed
METHODS : Unilateral
subcondylar fracture in 20
Wistar albino rats was used as a
fracture model . -
pubmed
CONCLUSIONS : As a result , our study showed that extracorporeal
shock wave therapy accelerated the improvement of
fractures in experimentally induced subcondylar
mandibular fracture in the
rat mandible . -
pubmed
OBJECTIVE : To evaluate the incidence of
subglottic stenosis in
children undergoing endotracheal intubation . -
pubmed
Children were then classified into two final groups : ' normal final examination ' , with no chronic changes ; and '
subglottic stenosis ' . -
pubmed
All the
children who developed
subglottic stenosis had had moderate to severe alterations immediately after extubation . -
pubmed
A 52 - year - old
man presented with severe
headache and mental deterioration with
memory disturbances and
bradypsychia . -
pubmed
METHODS : A total of 33 consecutive
patients ( mean age , 48.0 + - 11.6 years ) with acute Stanford
type A aortic dissection who underwent a total arch replacement were included in this study . -
pubmed
The causes of mortality were
multiorgan failure ( 4
patients ) ,
renal failure ( 1
patient ) , and
postoperative sepsis ( 1
patient ) . -
pubmed
Limb ischemia was observed in 4
patients , with all occurring in the lower limb . -
pubmed
Postoperative
delirium also was observed in 5
patients . -
pubmed
Here , we investigated the effects of
NOD2 deficiency on
cardiac hypertrophy induced by aortic banding ( AB ) in
mice . -
pubmed
Increased whole blood viscosity associated with arterial stiffness in
patients with
non - alcoholic fatty liver disease . -
pubmed
Therefore , this study aimed to investigate the association of WBV with baPWV in
patients with
NAFLD . -
pubmed
Essentially all cases of
cervical cancer , as well as a subset of other
anogenital and oral cancers are caused by this limited set of
HPV types . -
pubmed
RESULTS : In total , 67 % of
patients with severe
TBI had
cognitive impairment . -
pubmed
CONCLUSION : Findings highlight cognitive consequences of severe
TBI , with nearly two - thirds of
patients showing
cognitive impairments in at least 1 of 3 cognitive domains . -
pubmed
METHODS : Reachable workspaces were obtained from 22
individuals with
FSHD and 24 age- and height - matched healthy controls . -
pubmed
PATIENTS Y METHODS : One hundred consecutive surgically resected
patients with
pancreatic ductal adenocarcinoma were included in the study . -
pubmed
Determination using synchrotron radiation - based Fourier transform infrared microspectroscopy of putative stem cells in
human adenocarcinoma of the intestine : corresponding benign tissue as a template . -
pubmed
We obtained tissue sections containing small intestine and colon crypts derived from
normal ( benign ) or
adenocarcinoma ( AC )
human intestine . -
pubmed
Complete transitioning to the radial approach for primary percutaneous coronary intervention : a real - world single - center registry of 1808 consecutive
patients with acute ST - elevation
myocardial infarction . -
pubmed
CONCLUSION : Complete transition from femoral access to a preferred radial access is safe and effective for
STEMI patients undergoing PPCI , with a favorable effect on short- and long - term outcomes . -
pubmed
This study concluded that MPV , along with several other factors , may be used as a prognostic , independent , and therapeutic marker in
patients who are inclined to
thrombotic events after cesarean section . -
pubmed
Transcranial magnetic stimulation as an antidepressant alternative in a
patient with
Brugada syndrome and recurrent
syncope . -
pubmed
After an initial trial of
nortriptyline , the
patient 's
depressive symptoms improved ; however , he experienced a syncopal event and was subsequently diagnosed as having
BrS. -
pubmed
Given the potential lethality of
BrS with known and unknown psychopharmacologic agents , providers should consider
TMS as first - line therapy in this
patient population . -
pubmed
CONCLUSIONS : Patients with pulmonary MAC disease frequently had chronic co -
infections with pathogenic microorganisms such as
MSSA ,
P. - pubmed
In our recent work , we identified the structures induced by
IBV during
infection of
cultured cells , as well as primary cells and ex vivo organ culture . -
pubmed
We report on the case of a 3 - month - old
infant whose continuous
biliary obstruction caused by
IBS was successfully managed by interventional radiology with the association of
N - acetylcysteine and
glucagon . -
pubmed
Spuriously high platelet counts by various automated hematology analyzers in a
patient with
disseminated intravascular coagulation . -
pubmed
First record of autochthonous
canine ehrlichiosis caused by
Ehrlichia canis in Romania . -
pubmed
This case study describes the first genetically confirmed and clinically manifested autochthonous
Ehrlichia canis infection in a 9 - year - old female mixed - breed
dog from Romania . -
pubmed
This report supports the geographical expansion of
canine ehrlichiosis caused by
E canis in nonendemic regions of Europe . -
pubmed
A
TB vaccine should be safe and immunogenic as well as efficacious in all affected populations , including
HIV - infected individuals . -
pubmed
Psychiatric symptoms in
glioma patients : from diagnosis to management . -
pubmed
Patients with primary intrinsic
brain tumors can experience
neurological , cognitive , and psychiatric symptoms that greatly affect daily life . -
pubmed
Further research is needed to obtain a better estimate of the prevalence of
psychiatric symptoms in
glioma patients , and the extent to which these affect everyday functioning and family life . -
pubmed
OBJECTIVE :
Individuals carrying rare , but biologically informative genetic variants provide a unique opportunity to model major
mental illness and inform understanding of disease mechanisms . -
pubmed
This included family members with ( n = 7 ) and without ( n = 13 ) the translocation , along with a clinical control sample of
patients with
psychosis ( n = 34 ) , and a group of healthy controls ( n = 33 ) . -
pubmed
Many strategies and methods have been applied to reduce
CAUTI ; this article describes a quality improvement ( QI ) approach to the implementation of CAUTI prevention strategies , which can provide better
patient experience and outcomes for patients . -
pubmed
Understanding how axial loads on the spine influence segmental biomechanics for
idiopathic scoliosis patients : A magnetic resonance imaging study . -
pubmed
This study investigates the coronal plane segmental biomechanics for adolescent
idiopathic scoliosis patients in response to physiologically relevant axial compression . -
pubmed
METHODS : Individual spinal joint compliance in the coronal plane was measured for a series of 15
idiopathic scoliosis patients using axially loaded magnetic resonance imaging . -
pubmed
Here , four EOCs (
alpha - pinene ,
3 - carene ,
( + ) - limonene ,
( 1S )-(-)- beta - pinene ) were evaluated by disc diffusion assay ( DDA ) and growth inhibition assay ( GIA ) to determine inhibitory effects against five
strains of
S. - pubmed
PATIENT DESCRIPTION : We describe 14 years of follow - up of an
individual with
Hoyeraal - Hreidarsson syndrome who initially presented as an infant with
intrauterine growth retardation ,
microcephaly , and
central nervous system calcifications . -
pubmed
To focus on the 52
patients : median age was 69 years , 65 % were men and 35 % were women , 50 % had
haematologic cancers and 50 % had solid
tumours . -
pubmed
Clinical Reasoning : A 76 - year - old
man with acute - onset left - sided
weakness and
numbness . -
pubmed
Letter to the Editor regarding : " Treatment patterns and survival outcomes in
patients with
cervical cancer complicated by complete
uterine prolapse : a systematic review of literature " . -
pubmed
This finding correlated with partial rescue of spatial learning and
memory impairments in the Morris
water maze in comparison to APPSWE / PS1DeltaE9
mice . -
pubmed
BACKGROUND :
Patients on parenteral nutrition require a central venous access and are at risk of catheter - related
thrombosis ,
pulmonary embolism , and
vena cava syndrome . -
pubmed
Secondary outcomes were :
heparin - induced
thrombocytopenia , prevalence of anticoagulation , and quality of International Normalised Ratio management in
vitamin K antagonist - treated
patients . -
pubmed
Given that
mitochondrial dysfunction has been identified in fibroblasts , PBMC and brain samples from carriers as well as in
animal models of the premutation and that mitochondria are at the center of intermediary metabolism , the aim of the present study was to provide a complete view of the metabolic pattern by uncovering plasma metabolic perturbations in premutation carriers . -
pubmed
From the
rats that underwent oophorectomy , 10 formed the menopause control group ( Group 2 ) , 10 were administered a daily injection of
methylprednisolone until the end of the study ( Group 3 ) , and the remaining 10
rats were administered intraperitoneal
streptozocin to induce
diabetes mellitus ( Group 4 ) . -
pubmed
An 8 - yr - old male
golden lion tamarin (
Leontopithecus rosalia ) was diagnosed with
diabetes mellitus based on
hyperglycemia and persistent
glycosuria . -
pubmed
Following treatment with
exenatide , the persistent
glycosuria resolved , the
animal maintained normal blood
glucose concentrations , and had lower serum
fructosamine concentrations compared to pretreatment levels . -
pubmed
Gynura procumbens Extract Alleviates Postprandial
Hyperglycemia in
Diabetic Mice . -
pubmed
This study was designed to investigate the inhibitory effect of
Gynura procumbens extract against
carbohydrate digesting enzymes and its ability to ameliorate postprandial
hyperglycemia in
streptozotocin (
STZ)-induced
diabetic mice . -
pubmed
procumbens extract group than in the control group of
STZ - induced
diabetic mice . -
pubmed
procumbens extract administration in
STZ - induced
diabetic mice . -
pubmed
We selected 10 bacteria
strains , belonging to Bacillus ,
Staphylococcus and Serratia genera that are able to produce
3 - hydroxy-2 - butanone (
acetoin ) , a compound with proven growth promoting activity . -
pubmed
The BCT9
strain elicited the greatest increases in dry weight and primary root length when
L. - pubmed
Magnetic resonance elastography in a
rabbit model of
liver fibrosis : a 3 - T longitudinal validation for clinical translation . -
pubmed
This study aimed to determine the relationships between magnetic resonance elastography ( MRE ) imaging biomarkers and the stages of
liver fibrosis in a
rabbit model of
liver fibrosis , a longitudinal validation for clinical translation . -
pubmed
Liver fibrosis was induced in 38 male
New Zealand rabbits by weekly subcutaneous injections of 0.1 ml 50 %
carbon tetrachloride oily solution per kilogram of
body weight for 4 to 10 weeks to produced varying degrees of
liver fibrosis . -
pubmed
Re - assessing
acalculia : Distinguishing spatial and purely arithmetical deficits in right - hemisphere damaged
patients . -
pubmed
Arithmetical deficits in right - hemisphere damaged
patients have been traditionally considered secondary to
visuo - spatial impairments , although the exact relationship between the two deficits has rarely been assessed . -
pubmed
HIV significantly affects the immunological environment during
tuberculosis coinfection , and therefore may influence the selective landscape upon which
M. - pubmed
Following a review of the history of
human use and scientific study of these drugs , the data from clinical research are summarized , including extensive work on the use of classic hallucinogens in the treatment of
alcoholism and other addictions , studies of the use of
LSD and
psilocybin to relieve distress concerning
death , particularly in
patients with advanced or terminal
cancer , and more limited data concerning the use of classic hallucinogens to treat mood and
anxiety disorders . -
pubmed
To provide a clinical perspective , case summaries are provided of two
individuals who received treatment in recent controlled trials of
psilocybin : one being treated for
alcoholism , the other suffering from
anxiety and
depression related to fear of
death due to a
cancer diagnosis . -
pubmed
Glucose levels during hospitalization and incidence of
diabetes within 3 years after discharge in
patients without
diabetes were evaluated . -
pubmed
PATIENTS : Fifty - nine
patients over the age of 18 with computed tomography scans of the pelvis separated into 2 groups : a group with normal pelvic anatomy and a group with
sacral dysmorphism . -
pubmed
MATERIALS AND METHODS : Forty - one
patients ( mean , 52 years ; range , 18 - 77 years ) with severe
brain injuries were studied . -
pubmed
BACKGROUND : This systematic review and meta - analysis evaluated the short- and long - term outcomes of liver resection for
colorectal liver metastases ( CRLM ) in elderly
patients . -
pubmed
A
man with no history of
infection developed
cryptococcal meningitis and a right parahilar
cryptococcal mass . -
pubmed
Cancer cell lines of
human tissue origin have been extensively used to investigate antiproliferative activity and toxicity of herbal extracts , isolated compounds , and anticancer drugs . -
pubmed
In consequence , three dimensional ( 3D )
human hepatoma cell culture models are being developed as a resource to achieve these goals of simulating the in vivo
tumor microenvironment . -
pubmed
It is assumed that bioengineered 3D
hepatoma cell culture models can provide significant assistance in scrutinizing the molecular response of herbal natural products to recognize novel prognostic targets and crucial biomarkers in treatment strategies for
cancer patients in near future . -
pubmed
Gene microarray analysis of the circular RNAs expression profile in
human gastric cancer . -
pubmed
Human gastric cancer is a common
malignant neoplasm of the digestive system and represents a threat to
human health worldwide . -
pubmed
The present study identified circRNAs in the expression profile of
human gastric cancer that were potentially involved in the underlying molecular mechanisms of its development . -
pubmed
Background : A recent study demonstrated that inflammatory bone markers play a role in the antidepressant functions of
( R , S )- ketamine in treatment - resistant
patients with
depression . -
pubmed
METHODS : We included 1,066 probable
AD patients from the Amsterdam
Dementia Cohort ( n = 290 ) ,
Alzheimer ' s Disease Neuroimaging Initiative ( n = 268 ) ,
Dementia Competence Network ( n = 226 ) , and University of California , San Francisco ( n = 282 ) with available follow - up data . -
pubmed
Patients were previously clustered into two subtypes based on their neuropsychological test results : one with most prominent
memory impairment ( n = 663 ) and one with most prominent
non - memory impairment ( n = 403 ) . -
pubmed
CONCLUSIONS :
AD patients with most prominently
non - memory impairment show faster
disease progression and higher risk of mortality than
patients with most prominently
memory impairment . -
pubmed
In
humans , recent studies have correlated
AGD in boys to
testicular anomalies . -
pubmed
The aim of this study was to characterize in vitro the effect of autologous cartilage micrografts on chondrocyte viability and differentiation and perform an evaluation of their application in
racehorses affected by
joint diseases . -
pubmed
Preliminary data in the treatment of
racehorses are suggestive of a potential in vivo use of micrografts to treat
cartilage lesions . -
pubmed
Safety and efficacy of weekly versus three - weekly
paclitaxel plus
platinum neoadjuvant chemotherapy in
patients with locally advanced
squamous cell head and neck carcinoma : A pilot study . -
pubmed
In the present study , we prospectively assessed the safety and efficacy of weekly versus three - weekly
paclitaxel plus
platinum neoadjuvant chemotherapy in
patients with LA -
SCCHN . -
pubmed
Materials and Methods : We included 50 newly diagnosed
patients of LA -
SCCHN in the study and randomized them into two groups to receive either low - dose weekly ( 80 mg / sq . -
pubmed
Conclusion : Data from our small study suggest that weekly
paclitaxel plus
platinum neoadjuvant chemotherapy may be superior to the standard every 3 weeks ' administration in terms of safety as well as efficacy in
patients with
LA - SCCHN . -
pubmed
Microbial isolations were made from
Rhododendron catawbiense plants showing symptoms of wilt , dieback , and
death of shoots obtained from two nurseries in the Latium region in the late summer of 2012 . -
pubmed
To the best of our knowledge , this is the first report of
Phytophthora damage on Rhododendron caused by
P. - pubmed
The selection criteria included randomised controlled trials of the effect of
vitamin D supplementation ( 1000 - 4762 IU / day ) on pregnant
women with
gestational diabetes mellitus . -
pubmed
Prior studies show that
estrogens and neurogenic factors , including hypothalamic glutamatergic
NMDA receptor plasticity , play significant roles in
rodent hypertension . -
pubmed
Together , these findings reveal that early and late stage AOF female
mice display unique molecular signatures of long - lasting synaptic strength prior to , and following
hypertension . -
pubmed
Twenty - seven
infants & lt;= 1 year of age with
AS who underwent BAV from 2007 to 2017 were included . -
pubmed
Subjects with
MPHL or
FPHL received single injections of 7.5x106 , 1.5x106 or 3.0x105 DSC cells or a placebo in 4 randomized separate regions on their scalp , and hair densities and diameters were measured until 12 months later . -
pubmed
Reveals of New Candidate Active Components in
Hemerocallis Radix and Its Anti -
Depression Action of Mechanism Based on Network Pharmacology Approach . -
pubmed
Therefore , it is inferred that the root of
Hemerocallis fulva L. can be used as a therapeutic medicine for
depression . -
pubmed
BACKGROUND : Despite the increasing knowledge of the etiology of
neuropathic pain , this type of
chronic pain is resistant to available analgesics in approximately 50 % of
patients and therefore is continuously a subject of considerable interest for physiologists , neurologists , medicinal chemists , pharmacologists and others searching for more effective treatment options for this debilitating condition . -
pubmed
The
patient later passed away due to acute hypoxic
respiratory failure . -
pubmed
STUDY DESIGN : We performed a retrospective study based on
patients with
olfactory dysfunction . -
pubmed
Case summary : A 50 - year - old
woman was referred with a chief complaint of transient
chest pain ,
dyspnoea , and
paroxysmal thyroid swelling that usually developed after meals . -
pubmed
Then , we discuss our recent studies regarding paternal inheritance of the
tumor - augmenting effects in F2
mice by gestational
arsenite exposure , in which we investigated alterations of DNA methylation status in F2
tumors and causative F1 sperm . -
pubmed
Patients pre - induced with
MVI rarely require labour augmentation with
oxytocin . -
pubmed
Acute normovolemic hemodilution for a
patient with secondary
polycythemia undergoing aortic valve replacement due to severe
aortic stenosis - A case report . -
pubmed
Background : A high hematocrit level in
patients with
erythrocytosis is linked with increased blood viscosity and increased risk of
thromboembolism . -
pubmed
The preoperative hematocrit level of this
patient was very high due to secondary
polycythemia by
hypoxia . -
pubmed
We decided to perform acute normovolemic
hemodilution after anesthetic induction to reduce the risk of
thromboembolism in the
patient . -
pubmed
Conclusions : We estimate that
patients with secondary
polycythemia may benefit from acute normovolemic hemodilution to reduce their hematocrit levels while undergoing cardiac surgery using cardiopulmonary bypass . -
pubmed
Studies of
humans were included regardless of age , sex , ethnicity , and health status , with the exception of
IVD herniation . -
pubmed
The best evidence supports traditional ACL reconstruction for the surgical management of
patients with documented nonfunctional partial
tears of the ACL . -
pubmed
METHOD : We collected ( n = 31 ) cord blood samples from atopic mothers and followed up their
infants at 4 - 6 and 12 months of age for collection of peripheral venous blood samples and diagnosis of
AD . -
pubmed
Individual and combined effects of 5 - year exposure to
hyperandrogenemia and Western - style diet on metabolism and reproduction in female
rhesus macaques . -
pubmed
Hyperandrogenemia in the presence of a
WSD worsens metabolic function in female
nonhuman primates . -
pubmed
MAIN RESULTS AND THE ROLE OF CHANCE : After 5 years of treatment , WSD exposure moderately increased
body weight and body fat , although control
animals also had a high
body mass index due to ad libitum feeding . -
pubmed
LIMITATIONS , REASONS FOR CAUTION : The small sample size and heterogeneity in metabolic effects observed in the T + WSD group are limitations of the current study , with only a subset of
animals in this group showing impaired
insulin resistance relative to controls . -
pubmed
In addition ,
obesity in the C group prevented comparisons to lean
animals . -
pubmed
Paraneoplastic neurologic diseases (
PND ) are rare but can occur in
patients with common
malignancies including
breast cancer . -
pubmed
In
patients with
hormone receptor ( HR )- negative human epidermal growth factor receptor 2 ( HER2 )- positive breast cancer ,
PND have been reported in association with anti - Yo antibodies and with clinical presentation of
paraneoplastic cerebellar degeneration . -
pubmed
We describe the case of a
woman with progressively altered mental status and
seizures , ultimately requiring admission . -
pubmed
[ Specific prophylaxis of
colibacillosis and
salmonellosis in
lambs and
piglets ] . -
pubmed
Eight - year experience in conducting antithrombotic prophylaxis , by methods elaborated by the authors , in 93
patients operated on for acute
thrombosis in the system of venae cavae superior and inferior is generalized . -
pubmed
Effect of aging in two - stage
carcinogenesis on
mouse skin with
phorbol myristate acetate as promoting agent . -
pubmed
Life table analysis curves have been constructed for some of the data presented in a previous report on the effect of aging and of the interval between primary and secondary treatment in two - stage
carcinogenesis on
mouse skin . -
pubmed
In a herd of
pigs , 31 % presented serological reactions positive or doubtful to
brucellic infection ; in 15 % of the sows the mammary glands were swollen and purulent ; the retromammary
ganglions were enlarged and
hemorrhagic . -
pubmed
Bacteriological examination of the
pus of
mammary lesions showed the presence of
Brucella suis , which confirmed the diagnosis of
brucellic mammitis in the
sows . -
pubmed
Transgenic male M54 were crossed with female CBA / N
mice carrying the
Xid defect . -
pubmed
Ninety - seven consecutive
patients who underwent four different types of regional anaesthesia such as lumbar epidural , spinal , caudal and brachial blocks were studied for their incidence of
shivering . -
pubmed
This self - directed learning module highlights advances in the management of the
person with a
spinal cord deficit . -
pubmed
Traumatic spinal cord injury is being used as the model , but the principles apply to all
patients with
spinal cord deficits . -
pubmed
A basal , highly fortified diet was fed to all
pigs at 3 %
body weight daily . -
pubmed
Treatments consisted of the addition of
cassava chips at 0 , 1 , and 2 % of
body weight daily . -
pubmed
In anesthesized
dogs with closed chest and natural respiration massive
embolism of pulmonary artery has been simulated with the aid of marked
muscular emboli . -
pubmed
Identification of virus - specific antigens in
cultured cells infected with
Marek ' s disease virus serotype 2 and
CVI-988 strain . -
pubmed
This antigen was not found in cells infected with
Md / 5 and JM
strains of
MDV1 , and the results of kinetic analysis of antigen expression showed this antigen appeared to be related to late membrane antigens . -
pubmed
T - cell receptor gene rearrangements and the diagnosis of
human T - cell neoplasms . -
pubmed
After transurethral resection of the
tumour , all
patients received a course of radical radiotherapy , with salvage cystectomy for those who failed to respond . -
pubmed
Twenty - two of 23 ( 96 % )
patients with
tumours that had both these features did not respond to radiotherapy . -
pubmed
Nifedipine ( 10 mg tid ) or placebo was administered in a randomized double - blind trial for 1 wk to 2 groups of 10 mildly
hypertensive euthyroid
patients . -
pubmed
We have investigated the possible vascular changes induced by PDT in an intraocular
retinoblastoma - like
rat tumour model using the
86RbCl extraction procedure . -
pubmed
However , in terms of basic investigations of cell and tissue activity in grouped materials of
patients with
metabolic bone disease and the evaluation of treatment regimens in these materials , bone histomorphometric investigations still yield the most detailed analyses . -
pubmed
A
depression in aortic contractility has been previously demonstrated in
rat intraperitoneal
sepsis and during
endotoxemia . -
pubmed
Calcium influx stimulated by high
K + was unchanged in aortae between control and
septic animals . -
pubmed
In the presence of NE ,
calcium efflux ( an indirect measurement of intracellular
calcium release ) was significantly diminished ( P less than .001 ) in aortae from
septic rats . -
pubmed
In this study we have investigated the effect of repeated airway challenge with
AMP in 10 atopic ,
subjects without
asthma . -
pubmed
Intraocular inoculation of
herpes simplex virus type 1 (
HSV-1 ) in one eye of
rabbits results in
encephalitis and contralateral necrotizing
viral retinopathy . -
pubmed
Ipsilateral
retinopathy (
IR ) developed in 83 % of vitreous - inoculated
rabbits , but in only 5 % of AC - inoculated animals . -
pubmed
We investigated the therapeutic effects of
glycine in seven
patients with various forms of
myoclonus . -
pubmed
The control
patients included 10 with
noninfectious inflammatory diseases and 9 with
central nervous system infections . -
pubmed
Because of uncertainty about the place of hormones in the treatment of
postmenopausal bone loss vertebral and forearm bone loss was measured by absorptiometry in early postmenopausal
women before and after continuous or sequential treatment with combined
oestrogen and
progestogen in a double blind placebo controlled trial . -
pubmed
Before a policy of supplementation with hormones can be recommended to all postmenopausal
women with the aim of reducing the incidence of
vertebral crush fractures further studies with different doses and combinations of hormones , administered over several years , are needed . -
pubmed
Aerobic exercise may be helpful in many
patients , and administration of tricyclic compounds in very low doses is often effective in treating the associated
sleep disorder and in reducing overall disease severity . -
pubmed
Pituitary tumors induced by chronic
diethylstilbestrol (
DES ) treatment in female
F344 rats were treated subsequently with
bromocriptine ( BC ) . -
pubmed
Two
patients are presented with rare aseptic
osteonecrosis of the femoral head appearing during the last trimester of pregnancy . -
pubmed
Both
patients suffered from increasing
pain in one hip joint , beginning about one month before parturition . -
pubmed
Early shunt
thrombosis ( within 72 hours postoperatively ) occurred in 3
patients . -
pubmed
Pulmonary artery growth in
patients with
tetralogy of Fallot was greater than that in
patients with single ventricle , and the duration of palliation was acceptable in most
patients . -
pubmed
The anti -
human P component stained positively systemic amyloids and cerebral
amyloid plaques of
SSE , but failed to stain
senile plaques of
SDAT . -
pubmed
Natural
infections in
hartebeest , hyaena and lion in the Serengeti National Park , Tanzania . -
pubmed
Immune responses to
tumour and embryo cells in
patients with
mammary carcinoma . -
pubmed
[
Chronic steatorrhea in
children due to a
congenital insufficiency of pancreatic lipase ] . -
pubmed
IC were seen more frequently in
patients with
cirrhosis than in CAH
patients without
cirrhosis and
patients with
CPH . -
pubmed
LSP and LP-2 in IC were detected in 50 % of
patients with
CAH and , infrequently , in
CPH patients . -
pubmed
In a group of 56
patients with
CAH , followed for two to nine years , those
patients treated with
steroids showed a tendency to clear IC , whereas no variation was seen in untreated
patients . -
pubmed
Individuals suffering from the aversive symptoms of that
syndrome will be protected from excessive drinking and the related problems . -
pubmed
Effect of heart rate on myocardial blood flow in
dogs with
left ventricular hypertrophy . -
pubmed
Because of the previous suggestion that subendocardial perfusion may be inadequate in the hypertrophied heart , this study was carried out to examine the response of transmural myocardial blood flow to pacing induced
tachycardia in
dogs with chronic
left ventricular hypertrophy . -
pubmed
Myocardial hypertrophy , produced by banding the ascending aorta of puppies at 5 - 6 wk of age , resulted in an 87 % average increase in relative left ventricular mass compared with the control
dogs . -
pubmed
Increasing heart rates did not change the transmural pattern of myocardial blood flow in the normal
dogs , but in the animals with left
ventricular hypertrophy pacing at 250 beats / min resulted in a significant redistribution of perfusion away from the subendocardium , with the ratio of subendocardial / subepicardial blood flow falling from 1.03 + /- 0.08 at 100 beats / min to 0.83 + /0 0.06 at 250 beats / min ( P & lt ; 0.01 ) . -
pubmed
Mice continuously infused with the
vasopressin fragment
des - Gly9 -[ Arg8 ]- vasopressin dicitrate (
DGAVP ) throughout the periods of dependence induction and withdrawal testing exhibited exacerbated withdrawal
convulsions . -
pubmed
Psychogenic oligodipsia with
hypernatremia in a
psychotic patient . -
pubmed
Acute
anterior interosseous neuropathy in a
patient with
hereditary neuropathy with liability to
pressure palsies : a clinical and electromyographic study . -
pubmed
Methanolic extract ( CM - ext ) from tubers of
Corydalis turtschaninovii forma yanhusuo has been screened for activity in experimental models of
types I - IV allergy . -
pubmed
In type III allergic model , CM - ext showed the inhibitory effect on direct passive
arthus reaction ( DPAR ) in
rats . -
pubmed
The authors present a case of a 44 year old
woman with
Ebstein ' s Anomaly of the tricuspid valve . -
pubmed
[
Mediastinal abscess diagnosed after its
rupture into the trachea in a
patient after esophagectomy ] . -
pubmed
A 52 - yr - old
man with
esophageal cancer underwent esophagectomy and retrosternal reconstruction using stomach under general anesthesia . -
pubmed
In the postoperative period , the
patient developed mediastinal
abscess which failed to be diagnosed by daily routine chest X - rays , because of surgical alterations of mediastinal anatomy . -
pubmed
On the 11th postoperative day , the
abscess ruptured into the trachea and severe
hypoxemia ( PaO2 73 mmHg , FIO2 1.0 ) developed while the
patient was still on mechanical ventilation . -
pubmed
Although surgical drainage was not undertaken , the
patient 's severe
hypoxemia was resolved within 4 days by the supportive therapies including chest physiotherapy , postural drainage and administration of antibiotics and
corticosteroids . -
pubmed
The
HBM - M cell was originally derived from a
patient with
mastocytosis . -
pubmed
As
mastocytosis is thought to represent a reactive
hyperplasia rather than a
mast cell malignancy , the factor secreted by the
HBM - M cell strain could well be responsible for the
mast cell hyperplasia seen in some
patients with
mastocytosis . -
pubmed
We estimated the pharmacokinetic characteristics of
theophylline in
children with
bronchial asthma after multiple oral dosing of Theo - Dur , in order to determine whether the absorption of the drug is best described by a zero - order absorption kinetic model ( 0 - order model ) or a first - order absorption kinetic model ( 1 - order model ) . -
pubmed
Thirteen
children with
bronchial asthma were evaluated in this study . -
pubmed
METHODS : We studied 33 consecutive
patients with
lateral medullary infarction who showed appropriate MRI lesions and correlated their clinical findings with the MRI results . -
pubmed
CONCLUSIONS : Analysis of MRI findings in rostrocaudal and dorsoventral aspects allows us , although not unequivocally , to make anatomicoclinical correlations in the evaluation of
patients with
lateral medullary stroke syndrome . -
pubmed
We report a case of
NMS associated with
clozapine as a single agent that developed in a
patient with no prior history of
NMS . -
pubmed
In contrast to other reported cases of
NMS with
clozapine monotherapy in which
rigidity was reported to be absent , our
patient had classic
NMS with lead - pipe
rigidity . -
pubmed
NMS should be included in the differential diagnosis of a febrile
patient with a history of any neuroleptic treatment , including
clozapine . -
pubmed
In a randomised , placebo - controlled , double - blind study with parallel group comparison , the efficacy and tolerability of topical treatment with a
mucopolysaccharide polysulphate /
salicylic acid cream was investigated in 156
patients with acute
sprains of the knee or ankle joint . -
pubmed
In addition , we observed an inverse correlation between
body mass index and
obese patients with normal tolerance to
glucose . -
pubmed
Successful peripheral access was achieved in all
patients without
bleeding complications . -
pubmed
METHOD : Brief Psychiatric Rating Scale ( BPRS ) ratings were obtained in 70
patients with
schizophrenia or
schizoaffective disorder to determine their response to
clozapine compared with a typical neuroleptic . -
pubmed
Localisation of the
infection was the groin in 70
patients , abdominal aortic prostheses were involved in 16 , crural or extraanatomic prostheses in 13 cases . -
pubmed
METHODS : Stool ,
tumor , and mucosa samples were taken from 25
patients with colorectal
adenocarcinoma . -
pubmed
Stool and mucosa samples were obtained from 11 healthy
patients , and stool , pathologic bowel tissue , and
normal mucosa samples were obtained from 3
patients with
adenoma ( 1 ) or
ulcerative colitis ( 2 ) . -
pubmed
Known
HPV types have no association with
keratoacanthomas . -
pubmed
Certain
HPV types have been linked to the genesis and development of premalignant and malignant
skin diseases . -
pubmed
To further study the involvement of
HPVs in the aetiology of
KAs , we investigated paraffin - embedded specimens of 80 biopsies of
KAs for the presence of
HPV 1 , 2 , 3 , 4 , 5 , 7 , 26 , 37 , 38 , 47 and 59 DNA by in situ hybridization ( ISH ) with biotinylated probes under high stringency conditions ( Tm-10 degrees C ) . -
pubmed
Our results suggest that the known
HPV types are unlikely to have any role in the aetiology of
KAs . -
pubmed
Parainfluenza type 1 ( Sendai ) virus infection in young
rats induces
airway growth abnormalities associated with persistent
pulmonary dysfunction and hyperresponsiveness . -
pubmed
The objectives of this study were to compare virus - susceptible
brown Norway ( BN ) rats and virus - resistant
F344 rats and to determine which of several virus - induced
structural abnormalities , including
bronchiolar hypoplasia ,
alveolar dysplasia , bronchiolar mural
fibrosis , and increases in bronchiolar mast cells , were associated with virus - induced increases in pulmonary resistance and
hyperresponsiveness to
methacholine . -
pubmed
BN
rats infected with virus developed increases in respiratory resistance and
hyperresponsiveness that persisted for 28 to 65 d after inoculation . -
pubmed
F344 rats were resistant to significant virus - induced alterations in bronchiolar airway wall thickness and mast cell increases as well as to
pulmonary function abnormalities . -
pubmed
Acute , intravenous systemic
toxicity studies have been conducted in
sheep and
dogs . -
pubmed
CONCLUSIONS :
Ropivacaine produces
sensory and motor blockade which is similar to that produced by equal concentrations of
bupivacaine after epidural administration in the
sheep . -
pubmed
[ Experimental study on the therapeutic effects of
SMS201 - 995 on bile - induced acute
pancreatitis in the
dog ] . -
pubmed
We studied the effects of
SMS201 - 995 , a long - acting
somatostatin analogue , on bile - induced acute
pancreatitis in the
dog . -
pubmed
On the other hand , pancreatic blood flow showed a stronger decrease in SMS - treated
dogs than in non - treated ones , and a significant difference was observed at 15 minutes and 1 hour after induction of
pancreatitis . -
pubmed
Changes in intracellular and extracellular
calcium concentration of the myocardial cells during
heart failure in
children . -
pubmed
RESULTS : The concentration of ionized
calcium in myocardial cells and the erythrocyte was significantly higher in the
patients with
heart failure ( 280.85 + /- 47.8 nmol / L , 1.76 + /- 0.04 F335 / F385 ) than in those without
heart failure ( 121.88 + /- 13.15 nmol / L , 1.47 + /- 0.08 F335 / F385 ) . -
pubmed
Total
calcium in the erythrocyte was also increased markedly in the
patients with
heart failure , but the activity of the erythrocyte membrane pump was lower than in those without
heart failure . -
pubmed
We studied the magnetic resonance imaging ( MRI ) of 120 knees in 86
rheumatoid arthritis (
RA )
patients and of 14 unaffected knees in 12 control cases . -
pubmed
In the second experiment , we confirm these findings with a larger group of five pure
alexic patients using a selected subset of high- and low - visual complexity pictures . -
pubmed
Wild and mutant
strains of
Listeria monocytogenes are examined by electron and immunoelectron microscopy . -
pubmed
A
patient with acute
vertigo , and normal findings on neurologic examination , was found to have
vertebral artery dissection (
VAD ) . -
pubmed
Clinical experience and prospective treatment and outcome studies have demonstrated objective evidence of the efficacy of treating
patients with
chronic laryngitis symptoms with nocturnal antireflux precautions and acid - suppressing medications . -
pubmed
BACKGROUND : Skeletal muscle mass in genetically
obese ( ob / ob )
mice displays a reduced mass compared with their normal lean counterpart
mice . -
pubmed
Force production was unaltered in
obese mice . -
pubmed
CONCLUSION : Skeletal muscle from
obese mice is morphologically and functionally different from lean
mouse skeletal muscle . -
pubmed
Sixty
patients with a
hypertensive emergency ( mean arterial pressure & gt;130 mm Hg and evidence of
target organ damage ) were randomly divided into two groups of 30
patients each . -
pubmed
Mean arterial pressure decreased by 20.1 % : 148.3 + /- 12 to 118.6 + /- 9 mm Hg , p & lt ; 0.002 ; ten
patients suffered
headache . -
pubmed
Three
patients in Group A had a
subepicardial lesion in the first electrocardiograph , which disappeared with the use of the aerosol . -
pubmed
These results seem to indicate that
isosorbide dinitrate aerosol is better than tablets for the treatment of
patients with a
hypertensive emergencies . -
pubmed
Further , high T - cell - proliferative- and delayed - type
hypersensitivity responses were seen in Peyer 's patch - null
mice given oral OVA before systemic challenge . -
pubmed
Further , when delayed - type
hypersensitivity and splenic T cell proliferative responses were examined , Peyer 's patch - null
mice fed TNBS were unresponsive to
hapten . -
pubmed
A dose of 15 mg / m(2 ) body surface area was given to 14 prepubertal ( median age , 9.4 yr ; range , 6.1 - -10.8 yr ) , 20 pubertal ( median , 13.5 yr ; range , 10.6 - -16.8 yr ) , and 6 postpubertal ( median , 18.2 yr ; range , 17.2 - -20.3 yr )
patients with salt - wasting
CAH . -
pubmed
MATERIALS AND METHODS : The results are available of prehospital diagnosis of
MI in 1500
patients in 1992 - 1996 . -
pubmed
A new
strain of
Bacillus circulans isolated from a larva of
Culex quinquefasciatus showed larvicidal activity on 3 mosquitoes of medical importance . -
pubmed
The size of the
gastric lesions increased gradually after
ethanol exposure and was at its greatest after 4 h , in both young and old
mice . -
pubmed
We performed a randomized study of the effects of the herbal medicine dai - kenchu - to ( DKT ) on 24
patients with
PI . -
pubmed
In the
human hippocampus , magnetic resonance imaging studies have shown that there is a selective
atrophy in recurrent
depressive illness , accompanied by
deficits in memory performance . -
pubmed
We studied whether circulating activated platelets and platelet - leukocyte aggregates cause the development of
atherosclerotic lesions in
apolipoprotein - E - deficient ( Apoe (-/- ) ) mice . -
pubmed
Effects of cardiac resynchronization therapy on heart rate variability in
patients with chronic systolic
heart failure and intraventricular conduction delay . -
pubmed
BACKGROUND : A recently discovered DNA virus ( SEN ) has been assumed to be responsible for posttransfusion
hepatitis in
humans . -
pubmed
Phylogenetic analysis of
SEN virus has revealed the existence of 8 different
strains . -
pubmed
Two of them (
SEN virus strain H (
SENV - H ) and
SENV - D ) have been described as possible candidate viruses for inducing posttransfusion
hepatitis . -
pubmed
None of the solely
SENV - H - viremic individuals had clinical or biochemical signs of
liver disease . -
pubmed
Enhanced severity of
liver disease could not be observed in patients coinfected with
hepatitis C virus and
SENV - H. CONCLUSION : We conclude that
SENV - H viremia is widespread among hemodialysis patients . -
pubmed
Since no viremic patient had clinical or biochemical signs of
liver disease , in our setting the
hepatitis - inducing capacity of
SENV - H remains unclear . -
pubmed
Free
fatty acids in cerebrospinal fluids from
patients with
traumatic brain injury . -
pubmed
The present study examined
FFA concentrations in CSF from 15
patients with
traumatic brain injury (
TBI ) and compared the data with values obtained from 73 contemporary controls . -
pubmed
Concentrations of specific
FFAs from
TBI patients , obtained within 48 h of the insult were significantly greater than those in the control group (
arachidonic ,
docosahexaenoic and
myristic , P<0.001 ;
oleic ,
palmitic , P&
lt;0.01 ;
linoleic , P<0.05 ) . -
pubmed
Parasitic infestations in
man may cause transient or permanent
pulmonary lesions . -
pubmed
In this series , transient pulmonary changes were associated with
Ascaris lumbricoides ,
Ankylostoma duodenale ,
filariasis ,
Giardia lamblia and
Trichinella spiralis ; permanent lesions were produced by
Entameba histolytica and
Tenia echinococcus . -
pubmed
Liposomal
amphotericin B , and not
amphotericin B deoxycholate , improves survival of
diabetic mice infected with
Rhizopus oryzae . -
pubmed
The efficacies of liposomal
amphotericin B (
LAmB ) and
amphotericin B deoxycholate (
AmB ) were compared in a
diabetic murine model of hematogenously disseminated
Rhizopus oryzae infection . -
pubmed
These data indicate that high - dose
LAmB is more effective than
AmB in treating
murine disseminated
zygomycosis . -
pubmed
CLINICAL PRESENTATION : A 48 - year - old
man presented with an acute onset of right
visual deterioration after an episode of severe
headache . -
pubmed
CONCLUSION : Although there was no direct evidence of
subarachnoid hemorrhage on imaging scans or with operative exploration , we think that the
patient must have experienced sentinel
hemorrhaging , leading to
visual deterioration . -
pubmed
Numerous halogenated disinfection by - products ( DBPs ) occur and chronic ingestion has been associated with an increased risk for
colorectal cancer in
human populations . -
pubmed
[ Biological tests for diagnosis of
infections in artificial insemination of
cattle ] . -
pubmed
METHODS : Thirty
women with clinical symptoms of
vulvovaginal candidiasis ( 15 positive vaginal culture to
C. - pubmed
The objective of this review is to juxtapose the therapeutic potential of high and low concentrations of
ethanol in the treatment of
HCC , based on experimental studies obtained with the
human hepatocellular
tumor cell line (
HepG2 ) . -
pubmed
BACKGROUND : Measuring the circumference of the abdomen is still commonly used when treating a
patient with suspicion of
intra - abdominal bleeding . -
pubmed
METHODS : The study group consisted of 34
end - stage renal failure (
ERSF )
patients treated with peritoneal dialysis . -
pubmed
Evaluation of safety and efficacy of
gefitinib ( '
iressa ' ,
zd1839 ) as monotherapy in a series of Chinese
patients with advanced
non - small - cell lung cancer : experience from a compassionate - use programme . -
pubmed
CONCLUSION :
Gefitinib demonstrated safety and efficacy as monotherapy in this series of Chinese
patients with advanced
NSCLC and was also associated with remarkable symptom relief and improvement in QoL. -
pubmed
Arsenic compounds , which are well - documented
human carcinogens , are now used in
cancer therapy . -
pubmed
[ Specific
developmental disorders in
children ] . -
pubmed
Long - term follow - up CT scan evaluation in
patients with
pulmonary sarcoidosis . -
pubmed
OBJECTIVES : The aim of the present study was to determine how the pattern and extent of
sarcoidosis changes over time on serial high - resolution CT ( HRCT ) scans and to identify CT scan findings that might be helpful in predicting the prognosis of
patients with the disease . -
pubmed
METHODS : The initial and last HRCT scan findings of 40
patients with
pulmonary sarcoidosis during a mean follow - up period of 7.4 years ( range , 3 to 18 years ) were evaluated retrospectively . -
pubmed
The predominant patterns seen on the initial HRCT scan may be helpful in predicting the outcomes of
patients with
sarcoidosis . -
pubmed
The aim of this work was to investigate the interactions of
tumor cells with dendritic cells ( DC ) in normal donors and
patients with
multiple myeloma (
MM ) . -
pubmed
We reviewed our experiences with the management of sixteen pediatric cases ( 10
males , 6
females ; 11 - days to 14 - years old ) of
chylothorax and
chylopericardium from 1997 to 2003 . -
pubmed
Of the fifteen cases occurring after cardiothoracic surgery , thirteen patients had corrective or palliative surgery for complex
congenital heart disease , and two
patients had removal of
thymolipoma and
neuroblastoma , respectively . -
pubmed
Included also in this review was an 11 - day old preterm
infant with
hydrops fetalis and
congenital heart disease who developed
chylothorax . -
pubmed
The recently completed ACTION ( A
Coronary Disease Trial Investigating Outcome with
Nifedipine GITS ) trial provides further evidence that
nifedipine GITS can be used safely in high - risk
patients to treat
angina ,
lower blood pressure and significantly improve clinical outcomes . -
pubmed
We observed both significant inhibition of
tumour growth and extended survival of treated
mice . -
pubmed
Male - mediated
developmental toxicity in
mice after 8 weeks'exposure to low doses of X - rays . -
pubmed
PURPOSE : The aim of the study was to investigate the effects of subchronic irradiation of male
mice on reproduction ability and induction of male - mediated
teratogenesis . -
pubmed
The case of a bilateral total knee arthroplasty in a
hemophiliac patient is presented below . -
pubmed
The authors emphasize the importance of the adequate hematological and anaesthetical background when performing surgery in a
hemophiliac patient . -
pubmed
SUBJECTS : Fifty - seven
patients with
afebrile seizures fulfilling all of the following criteria were enrolled : ( 1 ) normal development prior to the onset , ( 2 ) no underlying disorders nor
neurological abnormalities , ( 3 ) onset before the age of four and ( 4 ) normal interictal EEG and neuroimaging findings . -
pubmed
RESULTS : Thirty - nine
cases ( Group A ) were characterized by an association of mild
gastroenteritis . -
pubmed
The remaining 18
cases were divided into two groups according to the
seizure type . -
pubmed
METHODS : Supine intravenous contrast - enhanced CTC with colonoscopic and/or surgical correlation was performed on 25
patients with colonic
adenomas or
carcinomas . -
pubmed
PARTICIPANTS : Six
patients were enrolled : five had symptomatic recurrent or residual WHO Grade I
meningiomas and one had an unoperated
anterior clinoidal meningioma . -
pubmed
One
patient was withdrawn from the study because of
myelosuppression and underwent further surgery . -
pubmed
CONCLUSIONS : From this small pilot study we conclude that although
hydroxyurea may be associated with disease stabilization in some
patients , it did not reduce
tumor mass and it caused significant side effects in some of our subjects . -
pubmed
Phase I / II study of
bortezomib plus
docetaxel in
patients with advanced
androgen - independent
prostate cancer . -
pubmed
Lindane toxicity in
pigeons . -
pubmed
The anti -
thrombotic active constituents from
Centella asiatica . -
pubmed
The in vitro effects of a
methanol extract from the aerial parts of
Centella asiatica on shear - induced
platelet activation and coagulation were assessed after oral administration to
rats , by subjecting non - anticoagulated blood to haemostatometry . -
pubmed
In spite of the long duration of this cutaneous marker of
internal malignancy , the
patient was completely asymptomatic and extensive investigations revealed the presence of widespread
metastasis of mucin secreting
signet cell adenocarcinoma from an unknown primary site . -
pubmed
In addition the
patient also had acquired
hypertrichosis lanuginose and florid
cutaneous papillomatosis which are also markers of
internal malignancy . -
pubmed
Children indicated as
tic - positive by the screening procedure were investigated using semi - structured questionnaires and the Polish version of YGTSS scale . -
pubmed
Abnormality of the hepatic vein waveforms in cirrhotic
patients with
portal hypertension and its prognostic implications . -
pubmed
CONCLUSIONS : Analyzing the HV waveforms was thus found to be a simple method for accurately assessing the prognosis in
cirrhotic patients with
portal hypertension . -
pubmed
METHODS AND RESULTS : Sixteen male
Wistar rats were randomly divided into two groups : normal control and
diabetic rats . -
pubmed
Diabetes mellitus was induced in
rats by
streptozotocin injection . -
pubmed
At 4 weeks
diabetic rats were associated with a lower
body weight ( BW ) and heart weight ( HW ) but a higher HW / BW . -
pubmed
We hypothesized that in
cancer patients with
respiratory insufficiency , systemic
hypoxemia may be related to enhanced aggressiveness of
cancer on one side and to the elevation of angiogenic factors on the other . -
pubmed
RESULTS :
Patients with systemic
hypoxemia had higher incidence rates of locally advanced
tumors . -
pubmed
Partial
oxygen pressure and blood
oxygen saturation were significantly lowered in
patients with T4
cancers as compared to less advanced ones . -
pubmed
Benzene , a carcinogen that can cause
cancer in
humans , may form at nanogram per gram levels in some beverages containing both
benzoate salts and
ascorbic or erythorbic acids . -
pubmed
Testicular germ cell carcinoma (
TGCC ) is the most common
malignancy among
men ages 20 to 34 years . -
pubmed
Implant - supported overdenture in an elderly
patient with
Huntington ' s disease . -
pubmed
The present paper reports on a
patient with
Huntington ' s disease who was rehabilitated with a mandibular overdenture supported by two endosteal implants . -
pubmed
To reduce the Legionella - linked risk in the several sites of Sud - Francilien Hospital , following a hospital - acquired
legionellosis case , a multidisciplinary working group performed an action plan monitored through
Legionella pneumophila counts in hot water supply . -
pubmed
Similar results were observed for three of the four establishments , whereas the last did not describe a pronounced reduction of
Legionella pneumophila counts and showed constantly serogroup 1
strains . -
pubmed
OBJECTIVE : To assess the electroanalgesia as an effective method in the reduction of
pain and consequent improvement in lung function in
patients undergoing coronary artery bypass graft surgery . -
pubmed
METHODS : During the period of one year were studied 30
patients undergoing surgery for treatment of the
ischemic coronary disease . -
pubmed
CONCLUSION : The group that did electroanalgesia presented reduction in the intensity of
postoperative pain , which however did not mean improvement in respiratory function of these
patients . -
pubmed
The authors also suggest methods to increase efficacy and safety of
levodopa therapy in
patients with
Parkinson ' s disease . -
pubmed
[ Effects of
beta - elemene on proliferation and apoptosis of
human multiple myeloma cell
RPMI-8226 ] . -
pubmed
This study was aimed to investigate the effect of
beta - elemene on proliferation and apoptosis of
human multiple myeloma cell line
RPMI-8226 and its mechanism . -
pubmed
The effect of
beta - elemene on the growth of
human multiple myeloma cell line
RPMI-8226 was detected by
MTT . -
pubmed
Genetic relationships between resistances to Fusarium head blight and
crown rot in
bread wheat (
Triticum aestivum L. ) . -
pubmed
A review was done with 25 scientific papers published in the past fifteen years with the objective to verify the effects of spray dried plasma added to diets for
pigs weaned at different ages on the feed intake ,
weight gain , intestinal structure , and number of
E. - pubmed
Beneficial effects of spray dried plasma were observed during the first week after weaning for
weight gain and feed intake of
piglets weaned at 14 , 21 , and 28 days old . -
pubmed
Here we study the
bleb - based motions of
Entamoeba histolytica in the constrained geometry of a micropipette . -
pubmed
BACKGROUND : A retrospective cohort study was performed in 1063
women diagnosed with
cervical intraepithelial neoplasia grade 3 (
CIN3 ) ( previously termed
carcinoma in situ- CIS ) in the National Women 's Hospital , Auckland , New Zealand . -
pubmed
Evaluation of prognosis in
patients with
respiratory failure requiring venovenous extracorporeal membrane oxygenation ( ECMO ) . -
pubmed
PURPOSE : In this study , we analyzed the respiratory status and the prognosis of
patients , including adults with acute
respiratory failure requiring venovenous extracorporeal membrane oxygenation ( VV ECMO ) to maintain respiratory status . -
pubmed
Its biosynthetic gene clusters have been identified in several
Streptomyces hygroscopicus strains , and a number of genes within the clusters have been functionally analyzed . -
pubmed
Arrhythmia occured in 12
patients ,
atelectasis in 6
patient and
pneumonia in 5
patients . -
pubmed
The FDA has approved Fortesta ( Endo ) , a topical gel , for
testosterone replacement therapy in adult
males with
hypogonadism . -
pubmed
METHODS : Biopsies were obtained 20 cm proximal to the anus from
individuals with quiescent
UC and from normal controls . -
pubmed
Some of these compounds , such as
N -( 2 - diethylaminoethyl )- 4 -[( 123 ) I ] iodobenzamide (
[ ( 123 ) I ] BZA ) and
[ ( 123 ) I ]- N -( 2 - diethylaminoethyl )- 2 - iodobenzamide (
[ ( 123 ) I ] BZA2 ) , have been successfully evaluated in
melanoma patients , showing high sensitivity and selectivity in the detection of
melanoma and its
metastasis ( 6 - 9 ) . -
pubmed
Spermidine BZA derivatives exhibit high affinity for melanin comparable to that of
[ ( 123 ) I ] BZA ; however , these compounds exhibit less accumulation in
tumors than
[ ( 123 ) I ] BZA in
animal models of
melanoma ( 13 ) . -
pubmed
METHODS :
Volunteers with or without
schistosomiasis were recruited and divided into a case group and a control group . -
pubmed
RESULTS : Two hundred and fifty - three
volunteers diagnosed with chronic or advanced
schistosomiasis in the case group showed different degrees of gastric mucosal changes , including 7 cases with schistosomal eggs deposited beneath the gastric mucosa ( with an incidence of 2.77 % ) , 33 cases with
dysplastic hyperplasia and intestinal
metaplasia ( with an incidence of
precancerous lesion of 13.04 % ) , and 1 case with
gastric cancer . -
pubmed
RESULTS : The final sample included 47,153
patients with traumatic
spinal cord injury . -
pubmed
RESULTS : In the
patients with
congenital tracheal stenosis , the pressure drop from the tracheal inlet to outlet , at flow rate 3L / min , ranged from 14 to 430 Pa ; the pressure drop at flow rate 7.3L / min ranged from 60 to 1825 Pa. -
pubmed
CONCLUSIONS : Simulations with computational fluid dynamics may provide an objective method to evaluate the severity of the symptoms in
patients with
congenital tracheal stenosis and may help guide treatment . -
pubmed
BACKGROUND : The purpose of this study was to assess select medication utilization prior to
duloxetine initiation among
patients with
major depressive disorder ,
generalized anxiety disorder ,
diabetic peripheral neuropathic pain ,
fibromyalgia , and
musculoskeletal pain associated with
osteoarthritis or
low back pain . -
pubmed
Using this method we have analyzed 132 controls and 130
Coronary Heart Disease (
CHD )
patients for plasma total
homocysteine , wherein , the mean plasma total
homocysteine levels were 10.51 + -8.36 and 11.51 + -10.06 mumol / L respectively . -
pubmed
Beneficiaries who had 4 years of observation with no
timolol use were categorized as " controls " and those with 2 years of non -
timolol glaucoma medication use followed by consecutive years of adjunctive
timolol use were considered " cases . " -
pubmed
Beneficiaries with 2 years of non -
timolol glaucoma medication use followed by 1 year in which they used
timolol adjunctively and then a year without
timolol use were considered " discontinuers . " -
pubmed
RESULTS : There were 24,271
glaucoma patients who did not receive
timolol ( controls ) , 1,406 beneficiaries who were prescribed
timolol in addition to other
glaucoma medications and continued its use ( cases ) , and 299 beneficiaries who used adjunctive
timolol for only a single year ( discontinuers ) . -
pubmed
Localization of
pandemic 2009 H1N1 influenza A virus RNA in lung and lymph nodes of fatal
influenza cases by in situ hybridization : new insights on virus replication and pathogenesis . -
pubmed
STUDY DESIGN :
Formalin - fixed , paraffin embedded autopsy tissues from 21
patients with confirmed
pH1N1 infection were analyzed by
influenza A IHC and by in situ hybridization ( ISH ) using
DIG - labeled sense ( detects viral RNA ) and antisense probes ( detects positive - stranded mRNA and cRNA ) targeting the nucleoprotein gene of
pH1N1 virus . -
pubmed
BACKGROUND : Development of a protective vaccine against
human immunodeficiency virus type 1 (
HIV-1 ) is an important subject in the field of medical sciences ; however , it has not yet been achieved . -
pubmed
Porphyromonas gingivalis is one of the oral microorganisms associated with
human chronic periodontitis . -
pubmed
Effects of co - administration of
candesartan with
pioglitazone on inflammatory parameters in hypertensive
patients with
type 2 diabetes mellitus : a preliminary report . -
pubmed
METHODS : Medical records of
gastroparesis patients were evaluated for physician management choices . -
pubmed
Seventy - one
patients who had undergone megaprosthesis reconstruction for previously unoperated localized lower - extremity
osteosarcoma were reviewed . -
pubmed
No
patient had evidence of
infection preoperatively . -
pubmed
Fevers ( body temperature of 38 C or higher ) were present in 62
patients ( 87.3 % ) at some point during the first 2 postoperative weeks . -
pubmed
Of the 62 febrile
patients , 94 % were relieved of
fever by postoperative day 5 . -
pubmed
Body temperature curves in
patients with
infection showed that several atypical patterns , such as multiple
fever peaks and persistent
fever , were accompanied by physical findings within the normalization period . -
pubmed
The effect of physiotherapy in addition to
testosterone replacement therapy on the efficiency of the motor system in
men with
hypogonadism . -
pubmed
BACKGROUND AND OBJECTIVE : The aim of this study was to analyze whether the addition of physiotherapy to
testosterone replacement therapy provides added benefit in improving functional capacity of the motor system in
men with
hypogonadism . -
pubmed
MATERIAL AND METHODS : The study involved 3 groups of
subjects : group 1 , healthy
men ( n=20 ) ; group 2 ,
men with
hypogonadism who underwent
testosterone replacement therapy with physiotherapy ( TRT+PT ) ( n=8 ) ; and group 3 ,
men with
hypogonadism who underwent
testosterone replacement therapy alone ( TRT ) ( n=10 ) . -
pubmed
CONCLUSIONS : Our results suggest that the application of
testosterone replacement therapy together with physiotherapy ( 1 hour twice weekly ) in
men with
hypogonadism may lead to earlier and better results in comparison with
testosterone replacement therapy applied alone . -
pubmed
Ninety - two per cent of the
influenza A viruses were pandemic A(H1N1 ) 2009 , and following antigenic analysis all of these were found to be similar to the current vaccine
strain . -
pubmed
Anti -
fatigue effect of
ginsenoside Rb1 on
postoperative fatigue syndrome induced by major small intestinal resection in
rat . -
pubmed
Ginsenoside Rb1 (
GRb1 ) , one of the principle active ingredients of
Panax ginseng , exerts multiple pharmacological activities to fight
fatigue . -
pubmed
In the present study , we investigate the anti -
fatigue effect of
GRb1 on
postoperative fatigue syndrome (
POFS ) in a
rat model induced by major small intestinal resection . -
pubmed
Patients with
FTLD ( n = 13 ) or
AD ( n = 13 ) and healthy controls ( n = 26 ) underwent a neuropsychological assessment and the socioemotional battery ( an empathy questionnaire , an emotion recognition task , and theory of mind tasks ) . -
pubmed
Mice underwent permanent
middle cerebral artery occlusion (
MCAO ) and were treated with one of the two cooling paradigms : one where cooling ( 30 C ) began at the onset of
MCAO ( early
hypothermia [ eHT ] ) and another where cooling began 1 hour later ( delayed
hypothermia [ dHT ] ) . -
pubmed
We studied the
genotoxicity of the commonly used OP pesticides
chlorpyrifos (
CPF ) ,
methyl parathion (
MPT ) , and
malathion (
MLT ) , individually and in combination , in
Wistar rat peripheral blood lymphocytes in vitro . -
pubmed
A 55 - year - old
woman with a past medical history of
methotrexate - controlled
RA presented with right leg
pain for 4 days . -
pubmed
Progressive
edema ,
pain , and
neuromuscular deficits persisted despite
steroid and antibiotic therapy , so the
patient was taken for urgent fasciotomy for
acute compartment syndrome . -
pubmed
Clinicians should be aware of this uncommon manifestation of
RA keeping the various presentations of
rheumatoid disease in mind when faced with these
patients . -
pubmed
METHODS : Data accruing prospectively from January , 2002 to September , 2013 yielded 53
SCA aneurysms in 53
patients . -
pubmed
Adult T cell leukaemia /
lymphoma (
ATLL ) is a rare
T lymphoproliferative disorder which is etiologically linked with
human T cell lymphotropic virus type-1 ( HTLV-1 ) . -
pubmed
PATIENTS AND METHODS : A total of 102
patients with a clinical diagnosis of
AA were admitted during the study period . -
pubmed
All the eligible
patients who finally diagnosed clinically as having
AA were planned for emergency open appendectomy . -
pubmed
On histopathology normal appendix was found in nine
patients ( 8.9 % ) ,
AA in 71
patients ( 69.6 % ) , complicated
appendicitis (
CA ) which includes perforated and gangrenous
appendicitis was present in 22
patients ( 21.5 % ) . -
pubmed
& gt;60 %
patients presented with
CA when the duration of
pain was & gt;72 h. Presence of appendicolith increased the probability of
CA . -
pubmed
These new findings suggest that replacement of defective cells in the inner ear of
hearing impaired patients using adult spiral
ganglion neurons may offer potential hope to improve the quality of life for
patients with
auditory dysfunction and
impaired hearing disorders . -
pubmed
Treatment for
individuals with documented
ASCVD or at high risk of developing
ASCVD begins with lifestyle changes ( adherence to a heart - healthy diet , exercise ,
tobacco avoidance , maintenance of a healthy weight ) and may also include
statin ,
fibrate , high - dose
fish oil , and/or
niacin therapy . -
pubmed
To delineate the characteristics of this
epileptic network , we collected EEG / fMRI data from 23
patients with
frontal lobe epilepsy . -
pubmed
For each
patient , EEG / fMRI analysis was first performed to determine the BOLD response to
epileptic spikes . -
pubmed
Nine features were used to evaluate the differences of
epileptic network patterns in three connection levels between
patients and controls . -
pubmed
DISCUSSION : The reported cases are explicative as they occurred in
patients suffering from different types of
cancer and with different causes of
BTcP. -
pubmed
[ Governance of
HIV /
AIDS organizations in Bobo - Dioulasso ( Burkina Faso ) ] . -
pubmed
In populations with low vaccine coverage , the live - attenuated Sabin
strains ,
OPV types 1 , 2 and 3 , can evolve into virulent vaccine - derived polioviruses (
VDPVs ) and circulate in the community . -
pubmed
OBJECTIVES : This study aimed to characterize virus isolates from four
AFP patients infected with
cVDPV2 in the Extreme North region of Cameroon in 2013 . -
pubmed
RESULTS : All four patients were infected by
cVDPV2 strains showing 1.2 - 2.0 % nucleotide difference compared to the reference Sabin 2 VP1 sequence . -
pubmed
Phylogenetic analysis indicated that the
VDPV strains were genetically linked to
cVDPV2 lineages of the recent Chad
cVDPV2 outbreak . -
pubmed
Pincer morphology could be assessed in 18
patients , with
coxa profunda in 14 ( 78 % ) and
acetabular retroversion in 6 ( 14 % ) . -
pubmed
Features of combined
pincer and cam impingement were observed in 4
patients ( 17 % ) . -
pubmed
Trichoscopic features of
frontal fibrosing alopecia : results in 249
patients . -
pubmed
The
rabbits showed no signs of
postoperative inflammation and
infection . -
pubmed
MATERIALS AND METHODS : Twenty male
Wistar rats were subjected to a midline laparotomy and a standard peritoneal and cecum abrasion
trauma . -
pubmed
OBJECTIVE : To determine the accuracy of BISAP score in finding out the frequency of severity and mortality in
patients with
acute pancreatitis by comparing it with Ranson 's score . -
pubmed
METHODOLOGY : Atotal of 80
patients who presented in emergency with acute
pancreatitis were included by consecutive non probability sampling technique . -
pubmed
CONCLUSION : The newly proposed BISAP score is a simple and accurate tool for severity stratification and is equally effective in finding out frequency of severity and in turns mortality in
patients with acute
pancreatitis as Ranson 's score . -
pubmed
We aimed to identify simple ultrasound parameters for the screening of
patients with unknown significant
chronic liver disease . -
pubmed
METHODS : Three hundred and twenty seven
patients with
chronic liver disease , liver biopsy , and ultrasound examination were included in the derivation set . -
pubmed
283 consecutive
patients referred for ultrasound examination were included in the validation set ; those selected according to the ultrasound parameters identified in the derivation set were then referred for specialized consultation including non - invasive
fibrosis tests and ultimately liver biopsy if
liver fibrosis was suspected . -
pubmed
CONCLUSION : The generalized search of three simple ultrasound signs in
patients referred for abdominal ultrasound examination may be an easy way to detect those with silent but significant
chronic liver disease . -
pubmed
Repeat doses of prenatal
corticosteroids for
women at risk of
preterm birth for improving neonatal health outcomes . -
pubmed
Treatment of
women who remain at risk of
preterm birth seven or more days after an initial course of prenatal
corticosteroids with repeat dose(s ) , compared with no repeat
corticosteroid treatment , reduced the risk of their infants experiencing the primary outcomes
respiratory distress syndrome ( risk ratio ( RR ) 0.83 , 95 % confidence interval ( CI ) 0.75 to 0.91 , eight trials , 3206 infants , number needed to treat to benefit ( NNTB ) 17 , 95 % CI 11 to 32 ) and serious infant outcome ( RR 0.84 , 95 % CI 0.75 to 0.94 , seven trials , 5094 infants , NNTB 30 , 95 % CI 19 to 79).Treatment with repeat dose(s ) of
corticosteroid was associated with a reduction in mean birthweight ( mean difference ( MD ) -75.79 g , 95 % CI -117.63 to -33.96 , nine trials , 5626 infants ) . -
pubmed
CONCLUSIONS : We found a novel anti - inflammatory function of
horsefly - derived cecropin - TY1 peptide , laying groundwork for better understanding the ectoparasite - host interaction of
horsefly with host and highlighting its potency in anti - inflammatory therapy for
sepsis and
endotoxin shock caused by Gram - negative
bacterial infections . -
pubmed
Melanotic neuroectodermal tumour of infancy (
MNTI ) is a rare , benign but locally aggressive
neoplasm of
infants commonly affecting the maxilla . -
pubmed
This Review outlines recent advances in the understanding of immunopathology , vaccine development and
human monoclonal antibodies produced against
dengue virus . -
pubmed
Expert consensus on the perioperative management of
patients with
sepsis . -
pubmed
While the dosage of many general anti -
tumor drugs is adjusted according to the
patient body surface area , one uniform dose of most TKIs is recommended regardless of body size . -
pubmed
The aim of this prospective controlled study was to investigate the levels of reactive
oxygen species ( ROS ) , including
asymmetric dimethylarginine (
ADMA ) , oxidative stress index ( OSI ) and total oxidant capacity ( TOC ) , and antioxidants with total antioxidant capacity ( TAC ) in peripheral and internal spermatic veins blood , the relationship of these factors with sperm parameters in the infertile
varicocoele patients , and the amelioration effect of varicocoelectomy on these outcomes . -
pubmed
BACKGROUND :
Liver fibrosis progresses faster in individuals coinfected with
human immunodeficiency virus ( HIV ) and hepatitis C virus (
HCV ) . -
pubmed
We present the case of a 5 - year - old
boy who developed a delayed onset intractable
hyperventilation following endoscopic third ventriculostomy . -
pubmed
METHODS AND MATERIALS : Using the 1998 to 2011 National Cancer Data Base , we identified 8273
women who underwent mastectomy for nonmetastatic
IBC . -
pubmed
Evaluation of kinematics and
injuries to restrained occupants in far - side crashes using full - scale vehicle and
human body models . -
pubmed
Panaxatriol saponins promotes angiogenesis and enhances cerebral perfusion after
ischemic stroke in
rats . -
pubmed
BACKGROUND :
Panaxatriol saponins (
PTS ) , an extract from the traditional Chinese herb
Panax notoginseng , which has been used to treat
ischemic stroke for many years in China . -
pubmed
METHODS :
Middle cerebral artery occlusion (
MCAO ) was induced in
rats , and
neurological deficit scores and
brain infarct volumes were assessed . -
pubmed
RESULTS : We showed that
PTS improved neurological function and reduced
infarct volumes in
MCAO rats . -
pubmed
CONCLUSIONS : With few alternative solutions able to address this unique and difficult problem , the structural block of vascularized bone with the extended corticoperiosteal sleeve proved able to achieve a union that had failed multiple previous attempts and able to resist reactivation of
infection , in a challenging group of
patients with comorbidities . -
pubmed
METHODS : We conducted a retrospective case series of 68
patients with biopsy - confirmed
paranasal sinus lymphoma with attention on systemic disease association . -
pubmed
RESULTS : Of 63
patients with
paranasal sinus lymphoma , 35 ( 56 % ) had systemic involvement . -
pubmed
Four
patient groups were identified : ( 1 ) primary
paranasal sinus lymphoma ( 44 % ) ; ( 2 )
systemic disease occurring concurrently with
paranasal sinus lymphoma ( 25 % ) ; ( 3 )
paranasal sinus lymphoma with
relapse of preexisting
systemic lymphoma ( 22 % ) ; and ( 4 ) progression to
systemic disease after primary
paranasal sinus lymphoma ( 8 % ) . -
pubmed
Most of the
patients with
systemic disease were diagnosed at 50 + years and had positive smoking histories . -
pubmed
For
patients with preexisting
systemic lymphoma , the mean time to
paranasal sinus lymphoma was 65 months . -
pubmed
Its expression was up - regulated upon
white spot syndrome virus (
WSSV )
infection . -
pubmed
Response to current
asthma therapies also varies greatly , which is probably related to the inter -
patient differences in pathogenesis . -
pubmed
To approach the problem whether it is reliable to deduce hypotheses from autopsy material to explain physiological and
pathological processes , we studied capillarity in
pig soleus muscle 1 and 24 hr after
death . -
pubmed
The 2015 - 2016
Zika virus (
ZIKV ) outbreak in the Americas has brought this relatively unknown flavivirus into the spotlight as the etiologic agent of
congenital Zika syndrome in newborns and , potentially , of
Guillain - Barre syndrome in adults . -
pubmed
ZIKV shares a high degree of
amino acid sequence homology with the closely related flavivirus
Dengue virus (
DENV ) . -
pubmed
Due to the paucity of research investigating T cell - mediated immune responses to
ZIKV , the precise roles of T cells in protection against and pathogenesis of
ZIKV infection are unclear . -
pubmed
In this review , we summarize our current understanding of how T cells respond to primary and
secondary infections with
DENV and
ZIKV . -
pubmed
A thorough understanding of the role of
ZIKV - specific and
DENV cross - reactive T cells in controlling
infection is essential for developing
ZIKV- and
DENV - specific vaccines with maximal safety and efficacy . -
pubmed
In a previous report we showed that intravenous infusion of bone marrow - derived mesenchymal stem cells ( MSCs ) improved functional recovery after contusive
spinal cord injury (
SCI ) in the non - immunosuppressed
rat , although the MSCs themselves were not detected at the
spinal cord injury (
SCI ) site [ 1 ] . -
pubmed
They could be interesting as anti -
CMV and anti -
tumor treatment . -
pubmed
Additional trials in
humans are required to assess the efficacy of
artesunate and
artemisinin derivatives in diseases other than
malaria . -
pubmed
A 34 - year - old
woman presented with left flank
pain and discomfort . -
pubmed
In this article , we attempt to review previous studies from the medical literature concerning
relapse and risk factors related to relapse in
BP patients . -
pubmed
Metabolic effects of light deprivation in the prefrontal cortex of
rats with
depression - like behavior : In vivo proton magnetic resonance spectroscopy at 7T. -
pubmed
Effect of chronic pretreatment with beta - blockers on no - reflow phenomenon in diabetic
patients with acute ST - elevation
myocardial infarction undergoing primary percutaneous coronary intervention . -
pubmed
In comparison with
patients attaining TIMI 3 flow ,
patients with no - reflow have an increased incidence of
ventricular arrhythmias , early
congestive cardiac failure ,
cardiac rupture and
cardiac death . -
pubmed
Methods and results : The study included 107 diabetic
patients who had presented with acute
STEMI within 12 h from the onset of
chest pain . -
pubmed
Conclusion : Chronic pre - treatment with B - blocker in
diabetic patients presenting with
STEMI , is associated with lower rate of occurrence of no - reflow phenomenon after primary PCI . -
pubmed
Here we investigated face processing in an adult ,
patient PK , diagnosed with both high functioning
autism spectrum disorder (
ASD ) and
developmental prosopagnosia (
DP ) . -
pubmed
CONCLUSIONS : The centralization of dispatch centers was associated with an improved bystander CPR rate and dispatcher - provided CPR instructions for
OHCA patients . -
pubmed
The functioning of middle ear bones in such
individuals were assessed in this study and it was found that the middle ear bones are equally susceptible to micro -
fractures and can cause reduction in the transmission of sound energy . -
pubmed
METHODS : The study included 25 normal , 39
osteopenic and 40
osteoporotic participants . -
pubmed
PURPOSE : To develop a new classification system for
vitreomacular traction ( VMT ) syndrome according to spectral - domain optical coherence tomography ( SD - OCT ) imaging and to investigate the clinical course of
VMT patients . -
pubmed
METHODS : This study included 68 eyes of 68 consecutive
patients who were followed with observation or treated with vitrectomy for idiopathic
VMT . -
pubmed
In the 44 eyes that were managed with vitrectomy , a significantly larger percentage of
patients in group C ( 4/16 [ 25 % ] ) experienced subsequent full - thickness
macular hole development following vitrectomy compared with those in groups B ( 0 % ) or C ( 0 % ) ( P = 0.014 ) . -
pubmed
METHODS : We retrospectively analyzed 860
patients with cT1 - 4N0M0
prostate cancer who underwent RARP ( n = 500 ) or VMAT ( n = 360 ) between 2011 and 2016 . -
pubmed
VMAT
patients had significantly better bRFS than RARP
patients , though their definitions of biochemical
recurrence differed . -
pubmed
Recent successes in
cancer immunotherapy have been tempered by sub - optimal clinical responses in the majority of
patients . -
pubmed
CONCLUSIONS : The MRI - stratified pathway detected more csPCa than the systematic TRUS - guided biopsy pathway in men with a clinical suspicion of
PCa , for both biopsy - naive
patients and those with prior negative biopsy . -
pubmed
Pressurized intraperitoneal aerosol chemotherapy with low - dose
cisplatin and
doxorubicin (
PIPAC C / D ) in
patients with
gastric cancer and
peritoneal metastasis : a phase II study . -
pubmed
Patients with
bowel obstruction or extraperitoneal
metastasis were ineligible . -
pubmed
Conclusions :
PIPAC C / D was well tolerated and active in
patients with
RGCPM . -
pubmed
However , the risk of
anaphylactic reactions , long treatment duration , varying extract quality , and underrepresentation of certain allergens currently prevent many
patients from successfully undergoing SIT . -
pubmed
In
patients who underwent MSA , the median reimbursement related to the upper
gastrointestinal disease was $ 305 PMPM , at 12 months prior to surgery and $ 104 at 12 months after surgery , representing 66 % decrease in cost . -
pubmed
Cholangiofibrosis and Related
Cholangiocellular Neoplasms in
Rodents . -
pubmed
METHODS : Sixty
patients with
T - ALL and 60
patients with
acute myelogenous leukemia (
AML ) diagnosed in our hospital from June 2012 to March 2015 were enrolled in
T - ALL group and
AML group , respectively . -
pubmed
Purpose : Circular RNA ( circRNA ) is a key regulatory factor in the development and progression of
human tumors . -
pubmed
However , the working mechanism and clinical significance of most circRNAs remain unknown in
human cancers , including
multiple myeloma (
MM ) . -
pubmed
Patients and Methods : This study employs high - throughput circRNA microarray with bioinformatics to identify differentially expressed circRNAs in
patients with
MM . -
pubmed
The hsa_circ_0007841 expressions were observed in the
MM tissues of 86
patients . -
pubmed
In addition , the relationship between hsa_circ_0007841 expressions in the
MM tissues and the pathological features of
patients with
MM were evaluated and role of hsa_circ_0007841 as a potential biomarker and therapeutic target was assessed . -
pubmed
Misoprostol ameliorates
doxorubicin induced
cardiac damage by decreasing oxidative stress and apoptosis in
rats . -
pubmed
We investigated the potential cardioprotective effects of
misoprostol ( MP ) on
doxorubicin (
DOX ) induced
cardiac damage using histologic and biochemical assessment of
rat heart . -
pubmed
Comparison of diagnostic sleep studies in hospitalized neurorehabilitation
patients with moderate to severe
traumatic brain injury . -
pubmed
RESEARCH QUESTION : This study aimed to evaluate the non - inferiority and diagnostic accuracy of a portable Level 3 sleep study relative to Level 1 polysomnography in hospitalized neurorehabilitation
patients with
traumatic brain injury . -
pubmed
The ultrastructural characteristics of bile canaliculus in
porcine liver donated after
cardiac death and machine perfusion preservation . -
pubmed
We analyzed the intracellular three - dimensional ultrastructure of the bile canaliculi and hepatocyte endomembrane systems in
porcine liver grafts after warm
ischemia followed by successive MP with modified University of Wisconsin
gluconate solution . -
pubmed
Focal EEG changes indicating
critical illness associated
cerebral microbleeds in a Covid-19
patient . -
pubmed
Objectives : We describe a
patient suffering from Covid19 - related
acute respiratory distress syndrome (
ARDS ) , highlighting the diagnostic role of the EEG in ICU . -
pubmed
History : A Covid-19
patient undergoing mechanical ventilation due to related
acute respiratory distress syndrome (
ARDS ) , presented altered mental status in the ICU . -
pubmed
EEG plays a crucial role in these
patients , allowing investigating the presence of focal or diffuse
cerebral dysfunction . -
pubmed
This is particularly helpful for Covid-19
patients in the ICU , where the neurological examination is challenging by the severity of the
respiratory illness . -
pubmed
OBJECTIVES : This study prospectively evaluated endomyocardial biopsies in
patients with
heart failure with preserved ejection fraction ( HFpEF ) to identify histopathologic phenotypes and their association with clinical characteristics . -
pubmed
METHODS :
Patients with
HFpEF (
EF > = 50 % ) referred to the Johns Hopkins HFpEF Clinic between August 2014 and September 2018 were enrolled for right heart catheterization and endomyocardial biopsy . -
pubmed
RESULTS : Of the 108
patients enrolled , median age was 66 years ( 25th to 75th percentile : 57 to 74 years ) , 61 % were women , 57 % were African American , 62 % had a previous
HF hospitalization , median
systolic blood pressure was 141 mm Hg ( 25th to 75th percentile : 125 to 162 mm Hg ) ,
body mass index (
BMI ) was 37 kg / m2 ( 25th to 75th percentile : 32 to 45 kg / m2 ) , and 97 % were on a loop diuretic . -
pubmed
Living donor kidney transplantation is an effective option of renal replacement therapy in
patients with
light - chain amyloidosis (
AL ) . -
pubmed
In the meantime , however , in addition to radon and
tobacco - smoke , other airborne pollutants have been identified as risk - factors for
lung - cancer . -
pubmed
While the general increase in life - expectancy improves the cost - effectiveness of radon remediation programmes significantly , reducing
tobacco - smoking incidence reduces that cost - effectiveness but with the overall benefit of reducing radon - related
lung - cancers . -
pubmed
OBJECTIVE : To determine the association between preoperative
Patient - Reported Outcomes Measurement Information System ( PROMIS ) Physical Function ( PF ) scores with
postoperative pain , narcotics use , and
patient - reported outcomes ( PRO ) following a single - level anterior cervical discectomy and fusion ( ACDF ) procedure . -
pubmed
Patients with greater disability reported higher VAS
pain scores ( P = 0.003 ) . -
pubmed
However ,
patients demonstrated similar improvement of VAS neck and arm
pain , as well as NDI at all postoperative timepoints . -
pubmed
CONCLUSION :
Patients with worse preoperative disability as measured by PROMIS PF reported increased
pain but comparable narcotics consumption in the immediate postoperative period following a single - level ACDF procedure . -
pubmed
Page kidney was described by Page , following very elaborate experiments with
animal kidneys in 1939 , with persistent arterial
hypertension from " cellophane
perinephritis . " -
pubmed
Patient was on
Apixaban , a non -
vitamin K antagonist oral anticoagulant ( NOAC ) for
atrial fibrillation which was withheld 3 days before the procedure . -
pubmed
METHODS : This study is a retrospective review of all
patients who underwent resection of a WHO grade I
intracranial meningioma at the authors ' institution from 2007 to 2017 . -
pubmed
Tumor recurrence occurred in 63
patients ( 12.8 % ) at a median ( IQR ) of 36 ( 40.3 ) months from surgery . -
pubmed
Klebsiella pneumoniae has emerged as one of the most important pathogens that frequently encounter in community - acquired or hospital - acquired
infections . -
pubmed
Timely epidemiological surveillance could greatly facilitate
infection control of
K. - pubmed
INTRODUCTION : The use of immune - checkpoint inhibitors has drastically improved the management of
patients with
non - small cell lung cancer (
NSCLC ) , but innate and acquired resistances are hurdles needed to be solved . -
pubmed
Syngeneic
NSCLC mouse models
393P and
UNSCC680AJ were used for in vivo drug testing . -
pubmed
Normal non - irradiated McCoy cell cultures provide a sensitive and reproducible method for the isolation of oculo - genital
strains of chlamydia A directly from
human secretions and for laboratory studies with these agents . -
pubmed
In 100 healthy persons and 38
patients with
idiopathic thrombocytopenic purpura (
ITP ) the morphology of thrombocytes was examined according to BREDDIN . -
pubmed
In the 36 months since its inception , the National
Prostatic Cancer Project treatment subgroup has randomly assigned over 360
patients with progressive advanced
prostatic cancer who were no longer responsive to endocrine manipulation to either one of four different clinical studies . -
pubmed
New trials will introduce single- and multiple - drug chemotherapy at earlier phases of the clinical course of
prostatic cancer patients . -
pubmed
Vaccinia virus infection of the central nervous system in X - irradiated
mice . -
pubmed
The effect of X - irradiation on experimental
vaccinia infection of BALB / c
mice was studied . -
pubmed
As compared with nonirradiated controls , the X - irradiated
animals exhibited ( i ) a time lag in virus replication ( delayed , but protracted replication ) ; ( ii ) a delayed and repressed immune response : ( iii ) more severe acute cytocidal
infection of leptomeninges , choroid plexus , ependyma , and vessels , with extensive damage to the brain - barrier system ; and ( iv ) noncytocidal , latent
infection of glial cells and neurons . -
pubmed
Hepatitis C virus (
HCV ) recently was shown to be a possible pathogenetic agent for
HCC in a number of countries . -
pubmed
Fifteen patients with positive findings for anti -
HCV had concurrent
HBV infection , 11 had serologic evidence of previous
HBV infection , and only 5 patients had anti -
HCV marker alone . -
pubmed
The mean age of
MPNT patients was greater than that of
Ewing ' s sarcoma patients . -
pubmed
Most importantly , however , was a statistically significant difference in prognosis : disease - free survival in
Ewing ' s sarcoma patients at 7.5 years follow - up was 60 % compared with 45 % MPNT patients ( P = 0.026 ) . -
pubmed
[
Malaria in intravenous drug users associated with
HIV seropositivity ] . -
pubmed
One case of induced
malaria by
Plasmodium vivax was registered in Presidente Prudente , located in the west of the State , in 1988 and a further eleven cases in 1989 . -
pubmed
Pre- and postoperative mammograms were reviewed in 103
women undergoing conservation surgery and irradiation for
breast cancer stage I. -
pubmed
Following surgery , 71 of the
patients displayed noticeable
scar tissue in the surgical area , sometimes causing diagnostic difficulties . -
pubmed
Two of the
patients had a local
recurrence of
carcinoma , while 3 developed
cancer in the other breast . -
pubmed
By 90 min the majority of
patients ( 55 % ) exhibited TIMI grade 3 flow ;
infarct artery patency at 120 min was 84.9 % . -
pubmed
During hospitalization definite recurrent
ischemia occurred in nine
patients ( 15 % ) ; nonfatal recurrent
infarction was noted in one ( 1.7 % ) . -
pubmed
Four
patients ( 6.7 % ) experienced major
bleeding , including one with
intracranial bleeding . -
pubmed
Mortality was significantly influenced by the occurrence of
cardiogenic shock , which was present in five
patients at the time of enrollment . -
pubmed
Forty - seven
adolescents with
periodontal abnormalities were examined using clinical , immunologic , and functional tests ( altogether 12 signs ) . -
pubmed
Of the 147
patients 12 developed
intracerebral , epidural and subdural hematomas . -
pubmed
3
persons developed
infections . -
pubmed
To investigate the clastogenic activity of sera from
leprosy patients , normal peripheral blood lymphocytes were cultured in both inactivated and noninactivated
lepromatous leprosy ( LL ) sera . -
pubmed
An increase in the frequency of
chromosome aberrations was observed in
normal lymphocyte cultures supplemented with both inactivated ( 5.2 % ) and noninactivated ( 5.0 % ) LL serum compared to that of cultures supplemented with normal
human AB+ serum ( 2.4 % ) . -
pubmed
The results obtained from the inactivated LL serum showed that the factor(s ) which induce
chromosomal damage , depress the mitotic index and the cell proliferation rate were not destroyed at 56 degrees C. These results are the first documentation of cytogenetic effects of LL sera on normal
human peripheral blood lymphocytes . -
pubmed
Effects of
hypoxia and
fatty acids on the distribution of metabolites in
rat heart . -
pubmed
Detection of
Leishmania donovani soluble antigen and antibody in the urine of
visceral leishmaniasis patients . -
pubmed
Urine samples from 21
patients with
visceral leishmaniasis were examined for the presence of
Leishmania donovani soluble antigen and antibody by double counter - current immunoelectrophoresis . -
pubmed
Growth failure in
children with
renal tubular acidosis . -
pubmed
[ Superiority of a new etiopathogenic treatment curing
periarteritis nodosa caused by
hepatitis B virus , using a combination of brief corticotherapy ,
vidarabine and plasma exchange ] . -
pubmed
A new physiopathological treatment of
HBV - related
polyarteritis inspired by advances in the treatment of
chronic active hepatitis B was tested in 7
patients . -
pubmed
In contrast , no patient had been cured in a similar group of 7
polyarteritis patients previously treated with the conventional symptomatic therapy using
corticosteroids ( 6/7 ) , plasma exchanges ( 4/7 ) and immunosuppressants ( 2/7 ) . -
pubmed
An open placebo - controlled study on eleven healthy
male volunteers was carried out to investigate renal tolerance and the possibility of
crystalluria after oral and intravenous administration of
ofloxacin . -
pubmed
[ Protective role of effectors and T - suppressors of delayed
hypersensitivity in
mice with a localized
staphylococcal infection ] . -
pubmed
To induce delayed
hypersensitivity (
DH ) in
mice , experimental local
infection with a small dose of
Staphylococcus aureus was used . -
pubmed
The study revealed that the role played by DH in antistaphylococcal immunity was different in the
animals infected by the subcutaneous routes ; besides , the regulatory action of T - suppressors of
DH was established . -
pubmed
Medroxyprogesterone acetate enhances spontaneous mammary tumorigenesis and
uterine adenomyosis in
mice . -
pubmed
Based on our previous findings that
medroxyprogesterone acetate (
MPA ) significantly suppressed the formation of preneoplastic mammary hyperplastic alveolar nodules in
mice , and that this suppression persisted for some time , we studied the effects of different schedules of
MPA treatment on spontaneous mammary
tumorigenesis and
uterine adenomyosis in
SHN virgin mice . -
pubmed
These results are in good accord with our previous observations with
progesterone , indicating that
MPA has
progesterone - like effects on
mammary and uterine lesions of
mice . -
pubmed
The records of 14
patients with a
tumour in the pineal or supra - sellar region seen at The Norwegian Radium Hospital , Oslo between 1973 - 1980 have been studied retrospectively . -
pubmed
The work presents the results of the study of the immune status in 18
patients with
chronic bronchitis at the stage of remission , subjected to prolonged prophylactic treatment with the inhalations of
levamisole solution , and in 16
patients receiving the inhalations of staphylococcal vaccine . -
pubmed
The determination of the sensitivity of lymphocytes and neutrophils to incubation with
levamisole by means of the rosette - formation test makes it possible to prognosticate , taking into account the initial level of spontaneous E - rosette formation of these cells , the effectiveness of the prophylactic treatment of
patients with
chronic bronchitis . -
pubmed
Varicella - zoster infection in
patients with
neoplastic diseases . -
pubmed
A neuron - survival assay with dissociated ciliary
ganglion neurons was used to examine the level of neurotrophic activity in organs of the
rat and
chicken . -
pubmed
In
patients with suspected
seizure disorders , electrical and clinical data should be correlated before interpretation is made of focal lesions seen by neuroimaging techniques . -
pubmed
Urinary incontinence developed postoperatively in 2 of 8
patients operated on solely because of symptomatic
genital prolapse . -
pubmed
Serum anticonvulsant levels during chronic administration in the immature
epileptic baboon ,
Papio papio . -
pubmed
The compositions of the major lipids and their constituent
fatty acids and
fatty aldehydes from cerebral gray matter , white matter , and myelin , spinal cord myelin , and sciatic nerve were determined in a 57 yr old
woman who died of
Refsum ' s disease . -
pubmed
Bronchial asthma observed in 2 of 16
workers ( 12.5 % ) was reactive in a skin drop test with 1 %
chloroplatinate , and typical
bronchial asthma was induced in an environmental provocation test carried out in a room where
platinum sensors are made . -
pubmed
The main symptoms revealed by physical examination of
workers exposed to chloroplatinate contact
dermatitis in 11 ( 78.6 % ) ,
pharyngeal irritation in 6 ( 42.9 % ) ,
nasal obstruction in 2 ( 14.3 % ) , frequent
sneezing ,
coughing , and sputum in one each. -
pubmed
Between October 1969 and December 1979 , a total of 440
patients who had diffuse
coronary artery disease were treated with combined endarterectomy and coronary bypass grafting . -
pubmed
Endarterectomy is a valuable additional procedure in the management of
patients with diffuse
coronary artery disease . -
pubmed
To investigate further the modulation of
autoimmune disease by nutritional means , the influence of
zinc deprivation upon the development of the immunopathology of MRL / I
mice was studied . -
pubmed
Because some effects of
zinc deficiency may be due to associated inanition and consequent caloric deprivation ,
mice with similarly restricted food intake but adequate
zinc intake were also studied . -
pubmed
When
zinc deficiency was introduced at 4 wk of age , a significant delay in the appearance of the physical findings of MRL / I
mice , including
open sores ,
necrotic ears ,
arthritis , and end - stage
cachexia , was noted . -
pubmed
In addition ,
zinc deficiency introduced at this age resulted in a lower incidence and titer of antibodies to dsDNA and less severe
glomerulonephritis than control
mice . -
pubmed
Pair - fed controls also showed delayed progression of their disease , but
animals restricted isocalorically from 4 wk of age experienced a more rapid onset of the
lupus - like syndrome than did their
zinc - deprived counterparts . -
pubmed
We evaluated 64
children with 72
ureteroceles who underwent operation . -
pubmed
Levels were significantly higher in
patients with
giant cell arteritis ( mean 2.04 ng / ml ) ,
polyarteritis nodosa ( mean 2.08 ng / ml ) ,
scleroderma ( mean 2.27 ng / ml ) , and
SLE ( mean 3.93 ng / ml ) . -
pubmed
CONCLUSION : Our findings may reflect a low degree of endothelial cell activation in healthy
persons that is increased in
inflammatory diseases involving blood vessels . -
pubmed
The growth and
rupture of 40
cerebral aneurysms was studied in 36
patients ( 14
men , 22
women ; were average age , 51.8 years ) . -
pubmed
The
adenoma patients all suffered
hypertension , whereas one of the
adenoma patients and the
carcinoma patient showed signs of
DM . -
pubmed
Thus , the present analysis of the six
incidentaloma patients suggests that once an
adrenal incidentaloma patient with
hypertension and/or
DM is found , both endocrinological and imaging examinations are necessary to determine the indication of surgical treatment . -
pubmed
In
patients with
hepatitis and
liver cirrhosis , the decrease did not , however , affect the
gamma - Gla excretion . -
pubmed
In addition , in
patients with
hepatoma or
carcinoma with
liver metastases , the urinary
gamma - Gla levels were increased . -
pubmed
However , in a series of seven consecutive
patients with severe
visual deficit due to
ethambutol toxicity , only 42.2 % ( 3 of the 7
patients ) achieved a visual recovery of better than 20/200 after an average follow - up of 8.3 + /- 2.1 months after stoppage of the drug . -
pubmed
As an additional sidelight , the value of visually evoked potential in the monitoring of
patients on
ethambutol , especially in cases with early
periaxial neuritis , has been emphasised . -
pubmed
Gas in the tissues -- a complication of pelvic surgery in the subclinical
diabetic patient . -
pubmed
The histopathology of the portal vein in
human extrahepatic portal vein obstruction (
EHPVO ) in the form of cavernomatous transformation of the portal vein is well documented . -
pubmed
An experimental model of
EHPVO was created by partial ligation of the portal vein in 20
rats . -
pubmed
Development of portal
hypertension was confirmed by measurement of intrasplenic pulp pressure ( 19.7 + 7.1 cm normal saline vs 12.9 + 1.1 cm of normal saline in SO
rats ) . -
pubmed
While SO
animals showed mild focal sinusoidal
congestion and a normal portal vein , the experimental group of
animals with
EHPVO showed
oedema around the portal vein , multiple dilated vascular channels near the hilum resembling cavernomatous transformation and severe sinusoidal
congestion . -
pubmed
Thus experimental
EHPVO does reproduce some histological changes observed in
human EHPVO . -
pubmed
Laser - Doppler flowmetry measurements of subcortical blood flow changes after fluid percussion
brain injury in
rats . -
pubmed
Laser - Doppler flowmetry ( LDF ) was used to record subcortical cerebral blood flow in hippocampus and striatum immediately following parasaggital fluid percussion
brain injuries of mild to moderate severity ( 2.58 + /- 0.09 atm , 10 - 11 msec duration ) in spontaneously breathing anesthetized
rats . -
pubmed
Subsequent beam - walk , beam - balance , and rope - hang assessments revealed significant
neurological impairments in the injured
rats but not in the sham controls . -
pubmed
Forty pediatric
patients , ranging from 5 - 13 years of age and suffering from
grass pollen rhinoconjunctivitis , were submitted to local nasal preseasonal ( 12 weeks ) immunotherapy , either with a
grass pollen extract or with placebo . -
pubmed
After only 1 year , the actively treated
patients showed a significant decrease of daily nasal and conjunctival
signs and symptoms - as judged by a 1 to 3 score - in comparison with the control group . -
pubmed
Impaired monocyte function in
patients successfully treated for
Whipple ' s disease . -
pubmed
Peripheral blood mononuclear cells ( monocytes ) from
patients with
Whipple ' s disease in long - term remission were tested for their ability to handle intracellular microorganisms . -
pubmed
[ Changes in brain
monoamine neurotransmitter in
iron deficiency nonanemic
rats ] . -
pubmed
An
iron deficiency nonanemic
rat model was established by feeding with low -
iron diet ( 11.9 mg / kg ) to study if there exists biochemical abnormality in brain tissues . -
pubmed
It indicated that there existed metabolic abnormality of
monoamine neurotransmitter in the brain tissues of
iron deficiency nonanemic
rats . -
pubmed
To calculate canal compromise and decrease of midsagittal diameter caused by retropulsion of fragments into the spinal canal we analyzed the pre- and postoperative computed tomographies of 32
patients with unstable thoracolumbar burst
fractures treated by USS ( universal spine system ) . -
pubmed
10 of 13
patients presented a postoperative improvement of
neurological deficit , no
neurological deterioration occurred . -
pubmed
[
Disorders of the blood microcirculation in
patients with suppurative - necrotic complications in
diabetes mellitus and the approaches to their correction ] . -
pubmed
The results of surgical treatment of 153
patients with
diabetes mellitus , suffering from purulent -
necrotic complications , were analyzed . -
pubmed
Ruby laser treatment for
hirsutism : clinical response and
patient tolerance . -
pubmed
The first treatment was followed by mild , short - lived
erythema and
swelling in 60 % ( 25 of 42 )
patients . -
pubmed
gamma delta T cells accumulate during
Plasmodium infections in both murine and
human malarias . -
pubmed
We examined the accumulation of gamma delta T cells elicited during
infection with virulent and avirulent
Plasmodium yoelii parasites in relatively susceptible and resistant
strains of
mice . -
pubmed
Effects of percutaneous balloon mitral valvuloplasty and exercise training on the kinetics of recovery
oxygen consumption after exercise in
patients with
mitral stenosis . -
pubmed
METHODS AND RESULTS : Thirty
patients with
mitral stenosis ( valve area & lt ; or = 1.0 cm2 ) and same sized age- and size - matched healthy
volunteers were included for this study . -
pubmed
Thirty consecutive
patients who underwent successful percutaneous balloon mitral valvuloplasty ( valve area & gt ; or = 1.5 cm2 and
mitral regurgitation grade & lt ; or = 2 ) , were randomized to an exercise training group or non - training group . -
pubmed
Spiral
nitinol biliary stents in a
porcine model : evaluation of the potential for use in benign
strictures . -
pubmed
Presynaptic inhibition in
humans : a comparison between normal and
spastic patients . -
pubmed
During the last 40 years , several studies in
man have been devoted to the pathophysiological mechanisms underlying
spasticity . -
pubmed
Delwaide showed that the vibration - induced inhibition of Ia fibres is reduced in
spastic patients . -
pubmed
This paper is thus devoted to a review of the methods recently developed to study selectively presynaptic Ia inhibition in
man and to a reevaluation of the relations between modifications in presynaptic Ia inhibition and
spasticity in
hemiplegic and spinal spastic patients . -
pubmed
HIV-1 infection can lead to severe central nervous system ( CNS ) clinical
syndromes in more than 50 % of
HIV-1 positive individuals . -
pubmed
PATIENTS : Eight
patients ( mean age , 55.1 + /- 12.1 yr ; mean duration to block , 4.4 + /- 3.7 mo ) with
chronic hemiplegia and severe
spasticity ( modified Ashworth scale [ MAS ] score & lt ; 2 ) secondary to
cerebrovascular accidents ( n = 5 ) and
traumatic brain injuries ( n = 3 ) . -
pubmed
The influence of
hemocoagulative disorders on the outcome of
children with
head injury . -
pubmed
BACKGROUND : Although
disseminated intravascular coagulation (
DIC ) and other
hemocoagulative abnormalities are severe complications of
head injury , their effect on clinical outcome remains unclear , particularly among
children . -
pubmed
OBJECTIVES : To evaluate the frequency of
hemocoagulative abnormalities and their influence on outcome among
children with
head injury . -
pubmed
RESULTS : Among
children with severe
head injury , 22.2 % ( 6/27 ) developed
DIC , all of whom died and had shown severe
brain edema . -
pubmed
The third case occurred in an
infant who died at birth and demonstrated a well - circumscribed
tumor that did not invade adjacent brain parenchyma . -
pubmed
BACKGROUND : Optical coherence tomography was used for the examination of
patients with
geographic atrophy in different stages of age - related
macular degeneration . -
pubmed
PATIENTS AND METHODS : 37
patients with
geographic atrophy ( n = 55 eyes ) out of 150 with
AMD ( n = 169 eyes ) were examined . -
pubmed
Risk of
cataract in
patients treated with
statins . -
pubmed
Clinical safety data of statins regarding
cataract development in
humans have been of limited value so far . -
pubmed
The main outcome was a first - time diagnosis of
cataract and/or
cataract extraction in
patients aged 40 to 79 years . -
pubmed
PATIENTS AND METHODS : From August 1994 to February 2000 , 285 consecutive
patients underwent endoscopic lithotripsy with either the Swiss Lithoclast pneumatic lithotripter ( 145
patients ) or the Ho : YAG laser lithotripter ( 140
patients ) for the treatment of
ureteral calculi . -
pubmed
Methicillin - resistant
Staphylococcus aureus (
MRSA )
nosocomial infections ( according to the definitions of
nosocomial infections ) of the Centers for Disease Control and Prevention in the surgical ward were retrospectively studied in two periods : from February 1989 to June 1990 and from January 1992 to December 1994 . -
pubmed
METHODS : Between January 1993 and December 1999 , a total of 62 consecutive
patients with
mitral valvular disease , whose preoperative left atrial endodiastolic volume index & gt;/= 300 ml / m(2 ) or endosystolic diameter & gt;/= 6.0 cm , were enrolled as research candidates . -
pubmed
CONCLUSION : The morphologic classification of
GLA may represent the main pathophysiological changes of
GLA and might be a guideline for the selection of the optimal plication procedures of
GLA in
patients with
valve diseases . -
pubmed
The ocular pharmacokinetics of a single topical administration of a fixed combination ( FC ) of
latanoprost 0.005 % and
timolol 0.5 % was compared to the monotherapies of
latanoprost and
timolol in
cataract surgery
patients . -
pubmed
Suppression of the
contact hypersensitivity response following topical exposure to
2 - butoxyethanol in female
BALB / c mice . -
pubmed
The effects of route of exposure , time of exposure and metabolism of
2 - butoxyethanol (
BE ) on the
contact hypersensitivity response ( CHR ) were evaluated in female
BALB / c mice . -
pubmed
Blocking the metabolism of BE by oral administration of
4 - methylpyrazole ( MP ) , further reduced
OXA - induced
ear swelling when compared to
mice exposed to BE without MP treatment . -
pubmed
METHODS : The cytopathology database at the New York University Medical Center was searched for
women who underwent surgical excision after a breast FNAB diagnosis of a
papillary lesion . -
pubmed
[ Development of experimental
tuberculosis in
guinea pigs treated with
thymol silver sulfone ] . -
pubmed
Because
inosine is able to enhance T - cell proliferation and reverse immunosuppression in vitro , both mechanisms may have aggravated the disease course in our
patient , once the autoimmune process of
dermatomyositis has been initiated . -
pubmed
In this patient ,
cystic lesions persisted after successful treatment of
Mycobacterium tuberculosis and resulted in spontaneous
pneumothorax with persistent air leak . -
pubmed
METHODS : PBMC from 30
patients allergic to pollen undergoing
SIT were collected during the therapy . -
pubmed
Control PBMC were collected from 10
patients with
allergic rhinitis not participating in SIT and from 10 nonallergic subjects . -
pubmed
Effect of challenge dose and age in experimental
infection of pigs with
encephalomyocarditis virus . -
pubmed
Two experiments were performed to compare the severity of
encephalomyocarditis virus ( EMCV ) infection in
pigs . -
pubmed
The
pigs were challenged with the Greek myocardial
strain , at different ages and with different doses . -
pubmed
In the first experiment , nineteen susceptible
pigs , 40 days old , were divided into three groups and were experimentally infected with 10(6 ) TCID(50 ) , 10(4 ) TCID(50 ) or 10(2 ) TCID(50 ) of the Greek
EMCV strain . -
pubmed
In the second experiment , 10 susceptible
pigs , of either 20 or 105 days , were divided into two groups according to age and were experimentally infected with 10(6 ) TCID(50 ) of the Greek
EMCV strain . -
pubmed
The severity of the macroscopical and the histopathological
heart lesions was inversely related to the age of the
pigs . -
pubmed
Viraemia , and nasal and faecal excretions were detected in all groups and lasted 1 - 3 days , except for the 105 - day - old
pigs whose symptoms lasted for an additional day . -
pubmed
Critics ignore or reject important evidence including , for example , large numbers of unexplained
HIV infections in children , strong associations between incident
HIV and injections , and genetically - linked
infections in persons with no known sexual contact . -
pubmed
In any case , because each
iatrogenic infection causes subsequent linked
infections , the impact of
HIV transmission through health care has been underestimated . -
pubmed
CONCLUSION : Baseline HRQL is a statistically significant predictor of survival for
patients with advanced
lung cancer . -
pubmed
The following were identified and analysed : type of
injury ( low or high - energy transfer ) , treatment ( early / late ) , complications ,
patient demographics and compliance . -
pubmed
Osteoporosis case finding in the general practice : phalangeal radiographic absorptiometry with and without risk factors for
osteoporosis to select postmenopausal
women eligible for lumbar spine and hip densitometry . -
pubmed
Different hemodynamic stress of the ascending aorta wall in
patients with
bicuspid and tricuspid aortic valve . -
pubmed
We performed an echocardiographic study to examine the differences in hemodynamic stress at the ascending aorta in
patients with
bicuspid and tricuspid aortic valve . -
pubmed
We studied prospectively 58 consecutive
patients referred for preoperative echocardiographic examination with
aortic valve stenosis and either bicuspid or tricuspid valve and an ascending aortic diameter of & lt;/=4.5 cm . -
pubmed
The second case was a 68 - year - old
woman followed for
hepatitis C associated with a mixed
cryoglobulinemia ( type II ) , who had sensory disturbances in the lower limbs . -
pubmed
Cerebrospinal fluid studies showed a normal protein content without
pleocytosis in both
patients . -
pubmed
CONCLUSIONS : This preliminary IVUS study suggests that ARB could cause regression of
coronary atherosclerosis in
humans . -
pubmed
BACKGROUND : Histological transformation (
HT ) is a well - known event in
patients with
follicular lymphoma (
FL ) conferring an unfavorable prognosis . -
pubmed
The aim of the study was to analyze incidence and risk factors for
HT in a large series of
FL patients . -
pubmed
PATIENTS AND METHODS : 276
patients ( median age : 54 years ; M139 / F137 ) diagnosed with
FL ( 42 % grade 1 , 51 % 2 , 7 % 3 ) in a single institution were studied . -
pubmed
RESULTS : 30 of 276
patients ( 11 % ) presented
HT after a median follow - up of 6.5 years , with a risk of 15 % and 22 % at 10 and at 15 years , respectively . -
pubmed
Only FLIPI predicted
HT in grade 1 - 2
patients . -
pubmed
No significant differences were found in incidences of
ventilator - associated pneumonia ( eight studies , 1,272
patients ) and mortality ( four studies , 1,062 patients ) . -
pubmed
METHODS : One hundred and one
patients with
MM and 101 healthy donors matched for age and sex were enrolled . -
pubmed
The role of
tobacco smoke induced
mitochondrial damage in
vascular dysfunction and
atherosclerosis . -
pubmed
The majority of individuals chronically exposed to
tobacco smoke will eventually succumb to
cardiovascular disease (
CVD ) . -
pubmed
However , despite the major cardiovascular health implications of
tobacco smoke exposure , concepts of how such exposure specifically results in
cardiovascular cell dysfunction that leads to
CVD development are still being explored . -
pubmed
Moreover , surprisingly little is known about the effects of prenatal and childhood
tobacco smoke exposure on adult
CVD development . -
pubmed
By virtue of its multiple , essential roles in cell function including energy production , oxidant signaling , apoptosis , immune response , and thermogenesis , damage to the mitochondrion will likely play an important role in the development of multiple common forms of
human disease , including
CVD . -
pubmed
Specifically , this review will discuss the potential role of
tobacco smoke and environmental oxidant exposure in the induction of
mitochondrial damage which is related to
CVD development . -
pubmed
Aspects of both adult and developmental ( fetal and childhood ) exposure to
tobacco smoke on
mitochondrial damage , function and disease development are also discussed , including the future implications and direction of studies involving the role of the mitochondrion in influencing
disease susceptibility mediated by environmental factors . -
pubmed
The current study aimed to determine these excretions in
patients with
Parkinson ' s disease (
PD ) receiving
L - dopa compared with suitable controls . -
pubmed
METHODS : Using one - way analysis of variance ( ANOVA ) , urine
catecholamines and metabolites , expressed as mmol per mole
creatinine , were compared in :
patients with
PD who were receiving
L - dopa ;
patients with
PD but not receiving
L - dopa ; and
patients without
PD who were being investigated for the presence of
phaechromocytoma but were found not to have the disease . -
pubmed
RESULTS : Significantly higher values for urinary
dopamine ,
homovanillic acid , free
normetadrenaline and free
metadrenaline were found in
patients with
PD receiving
L - dopa compared with the other two control groups . -
pubmed
In all the
patients with
PD , these four analytes were significantly correlated with daily dose of
L - dopa . -
pubmed
METHODS :
Patients with treatment - resistant morbid
obesity were invited to participate in a randomized , double - blind , sham - controlled trial of 4 - month duration . -
pubmed
Comparison of
postoperative complications of 60- and 70 - year - old
patients after lung surgery . -
pubmed
Clinical studies have demonstrated that islet transplantation may be a useful procedure to replace beta cell function in
patients with
Type 1 diabetes . -
pubmed
Symptomatic
candidiasis : Using self sampled vaginal smears to establish the presence of Candida , lactobacilli , and
Gardnerella vaginalis . -
pubmed
Efficacy of
nitazoxanide against experimental
cryptosporidiosis in
goat neonates . -
pubmed
METHODS : Eighty
patients with difficult endoscopic sphincterotomy because of
periampullary diverticulum or prior sphincterotomy underwent balloon dilatation ( n=46 ) or sphincterotomy ( n=34 ) for lithotripsy . -
pubmed
BACKGROUND : Management of
patients with an
abdominal aortic aneurysm (
AAA ) and
malignancy is challenging . -
pubmed
METHODS : The outcomes for
patients diagnosed with
AAA and
lung cancer between 1991 and 2004 at our institution were reviewed retrospectively . -
pubmed
RESULTS : We identified 75
patients with both lesions among 1,096
AAA and 1,875
lung cancer patients . -
pubmed
Treatment for
AAAs greater than 5.5 cm should be based on stage , histology , and
patient comorbidities . -
pubmed
Strong cytoplasmic incompatibility and high vertical transmission rate can explain the high frequencies of
Wolbachia infection in Japanese populations of
Colias erate poliographus ( Lepidoptera : Pieridae ) . -
pubmed
We found that the Wolbachia
infection frequencies of the butterfly
Colias erate poliographus were high ( 85.7 - 100 % ) in seven Japanese populations . -
pubmed
As part of studies of metabolites from fungi common in the built environment in Canadian homes , we investigated metabolites from
strains of three Eurotium species , namely
E. - pubmed
METHODS : This was done by assessing changes in
caries prevalence in the mouth of
children aged 12 to 14 year- old . -
pubmed
Dobutamine enhances alveolar fluid clearance in a
rat model of
acute lung injury . -
pubmed
Acute lung injury (
ALI ) and its most severe form ,
acute respiratory distress syndrome (
ARDS ) , remain leading factors for morbidity and mortality in
critically ill patients . -
pubmed
The present study was designed to determine whether the administration of
dobutamine decreases
pulmonary edema and stimulates AFC in a
rat model of lipopolysaccharide - induced
lung injury . -
pubmed
However the understanding of pulmonary
vascular remodeling in
patients with
CTEPH is incomplete . -
pubmed
Pulmonary endarterectomy of the obstructing
thromboembolic material should be performed in
patients who are accessible to surgery . -
pubmed
In
patients who are judged inoperable or with persistent
pulmonary hypertension treatment with
pulmonary arterial hypertension medications can be considered . -
pubmed
Tuberculosis caused by
Mycobacterium microti in South American camelids . -
pubmed
BACKGROUND :
Infection with
Mycobacterium microti can cause
chronic disease in animals and threaten
human health through its zoonotic potential . -
pubmed
METHODS : Description of 10
llamas and 1
alpaca , aged 4 - 18 years , from 6 herds with a history of
wasting and
weakness admitted to the Vetsuisse - Faculty of Berne over 8 years . -
pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE :
Infection caused by
M. - pubmed
microti infection have been reported in immunocompromized
human patients , the zoonotic potential of the organism should be kept in mind when dealing with this disease in
SAC . -
pubmed
The evaluation of vestibular functions in
patients with
pseudoexfoliation syndrome . -
pubmed
The main objective of the study is to evaluate vestibular system of the inner ear with postural tests in the
patients with
pseudoexfoliation syndrome (
PEX ) . -
pubmed
The study group included 34
patients with
PEX and 40 controls without
PEX . -
pubmed
Although none of the 34
patients with
PEX had clinical history of
balance disturbance , 21 ( 61.76 % ) had significant pathologic sign in vestibular function tests ( P & lt ; or = 0.05 ) , while only 3 ( 7.5 % ) of 40 cases in the control group had pathologic sign in vestibular function tests . -
pubmed
In conclusion , the
patients with
PEX , there may be a vestibular involvement in the pathological level in the inner ear . -
pubmed
Larger clinical studies , experimental
animal studies , and post mortem studies in
humans are needed to disclose the pathology in the vestibulocochlear system in the
patients with
PEX . -
pubmed
Human U-87 MG and
U-118 MG
glioma cells and
rat C6 glioma cells were chosen for the study . -
pubmed
The scaffolds pre - cultured with
U-87 MG and
C6 cells were then implanted into
nude mice to evaluate
tumor growth and blood vessel recruitment compared to the standard 2D cell culture and 3D Matrigel matrix xenograft controls . -
pubmed
Coffee and
tea consumption and
endometrial cancer risk in a population - based study in New Jersey . -
pubmed
We evaluated the role of
tea and
coffee and substances added (
sugar / honey , creamers , and milk ) on
endometrial cancer risk in a population - based case - control study in six counties in New Jersey , including 417 cases and 395 controls . -
pubmed
Our results indicate that
sugars and milk / cream added to
coffee and tea should be considered in future studies evaluating
coffee and tea and
endometrial cancer risk . -
pubmed
Here , by using
human specimens and three
mouse models of
ovarian cancer , we tested the feasibility of nonlinear imaging approaches , the multiphoton microscopy ( MPM ) and second harmonic generation ( SHG ) to serve as complementary tools for
ovarian cancer diagnosis . -
pubmed
SUMMARY OF BACKGROUND DATA : IVC filters are increasingly being used as prophylaxis against
postoperative pulmonary embolism in
patients undergoing bariatric surgery , despite a lack of evidence of effectiveness . -
pubmed
BACKGROUND : The prognosis for
patients with
extensive - stage small - cell lung cancer remains poor . -
pubmed
Six
patients did not begin treatment with
imatinib because of
disease progression , persistent
toxicity , or referral for radiation therapy . -
pubmed
The
irinotecan /
cisplatin regimen was well tolerated ( grade 1/2
neutropenia , 29 % ;
anemia , 43 % ;
thrombocytopenia , 14 % ; and
diarrhea , 29 % ) , except in 1
patient with grade 3
vomiting . -
pubmed
Imatinib toxicity included grade 1/2
nausea in 50 % of the
patients ,
peripheral edema in 75 % of the
patients , grade 3
fatigue in 13 % of the
patients , and
neutropenia in 13 % of the
patients . -
pubmed
These methods were translated to
rodent , large
mammal , and
human kidneys , and then to
rodent and
human tissues with advanced
CKD . -
pubmed
Comparative in vitro studies demonstrated that phenotype and key functional attributes were retained consistently in ex vivo cultures regardless of species or disease state , suggesting that autologous sourcing of cells that contribute to in situ kidney regeneration after
injury is feasible , even with biopsies from
patients with advanced
CKD . -
pubmed
This fat - soluble vitamin should be measured in
patients who have undergone gastric bypass surgery and deficiency should be suspected in those with evidence of
protein - calorie malnutrition . -
pubmed
Exclusive and adjuvant radiotherapy in
breast cancer patients with synchronous
metastases . -
pubmed
However , several studies suggest that surgical excision of the primary
tumor can prolong these
patients ' survival . -
pubmed
Here we discuss current issues regarding exclusive and adjuvant locoregional radiotherapy in
breast cancer patients with synchronous
metastases . -
pubmed
SUMMARY : Several studies suggest that surgery or exclusive irradiation of the primary
tumor is associated with better survival in
breast cancer patients with synchronous
metastases and that exclusive locoregional radiotherapy may represent an effective alternative to surgery in this setting . -
pubmed
Results of well - designed prospective studies are needed to re - evaluate treatment of the primary
breast tumor in
patients with
metastases at diagnosis , and to identify those
patients who are most likely to benefit . -
pubmed
A larger 9.5Mb deletion ( 34.6 - 43.9Mb ) was observed in a 20 - year - old
man with a more severe clinical picture including
seizures and limited speech . -
pubmed
All compounds isolated were evaluated for their
cytotoxicity against
HL-60 ,
A549 , and
MCF-7 human cancer cell lines . -
pubmed
Appropriate hearing screening in the pediatric
patient with
head trauma . -
pubmed
PURPOSE : To develop an algorithm for the appropriate audiologic screening of in
children with
head trauma . -
pubmed
METHODS : Participants were the first consecutive 50
children admitted to a
children 's hospital
trauma service after October 1 , 2005 , whose
injuries resulted in a Glasgow Coma Scale ( GCS ) score & lt;=13 and/or
loss of consciousness ( LOC ) but no history of
hearing loss . -
pubmed
CONCLUSIONS : Any
child with
head trauma and clinical or radiologic evidence of
temporal bone fracture should have early hearing evaluation . -
pubmed
The authors report a case of a cervical periosteal
chondroma in a 38 - year - old
man presenting with
neck pain and a syndrome of
spinal cord compression . -
pubmed
This article reports on new neuroimaging markers for the diagnosis of
Alzheimer ' s disease and particularly recent multi - functional magnetic resonance imaging ( m - fMRI ) studies in
patients with
schizophrenic and
affective psychoses . -
pubmed
INTRODUCTION :
Lenalidomide is an IMiDs oral immunomodulatory compound developed for the treatment of
patients with
multiple myeloma (
MM ) and
myelodysplastic syndromes (
MDS ) . -
pubmed
The necessity for early adverse - event management , including dose modifications for
neutropenia and
thrombocytopenia , and
venous thromboembolism prophylaxis , where applicable , in order to maintain
patients on treatment and achieve optimal efficacy , is discussed . -
pubmed
Secondary primary
malignancies in
MM and progression to
acute myeloid leukemia in
MDS patients in the context of
lenalidomide treatment are also discussed . -
pubmed
PATIENTS AND METHODS : Retrospective study of 14
patients with 15 Bosniak type 2F and 3
renal cysts on contrast enhanced CT . -
pubmed
BACKGROUND : Previous work indicates that single word intelligibility tests developed for
dysarthria are sensitive to segmental production errors in aphasic
individuals with and without
apraxia of speech . -
pubmed
Target of
rapamcyin (
TOR)-based therapeutics for
cardiomyopathy : insights from
zebrafish genetics . -
pubmed
BACKGROUND :
Hypothermia is becoming a common treatment for
newborns with
hypoxic ischaemic encephalopathy . -
pubmed
Using a
5alpha - dihydrotestosterone (
DHT)-induced
rat model that recapitulates the reproductive and metabolic phenotypes of
human PCOS , we have examined the steroidogenic capability of granulosa cells from
DHT - treated
rats . -
pubmed
Acute
Delta ( 9 )- tetrahydrocannabinol blocks
gastric hemorrhages induced by the nonsteroidal anti - inflammatory drug
diclofenac sodium in
mice . -
pubmed
Although inhibitors of endocannabinoid catabolic enzymes protect against
gastropathy in fasted
NSAID - treated
mice , the gastroprotective effects of
Delta ( 9 )- tetrahydrocannabinol (
THC ) , the primary psychoactive component of marijuana , have yet to be investigated . -
pubmed
In separate groups of
mice , the cannabimimetic behavioral effects of
Delta ( 9 )- THC given via each route of administration were compared using a battery of tests , consisting of assessment of locomotor activity , nociception in the tail withdrawal test ,
catalepsy in the bar test , and
hypothermia . -
pubmed
Bone mineral loss induced by anticancer treatment for
gynecological malignancies in premenopausal
women . -
pubmed
METHODS : This study enrolled 35 premenopausal
women ( 15
ovarian cancers (
OCs ) , 9
endometrial cancers (
ECs ) , and 11
cervical cancers (
CCs ) ) who underwent surgical treatment that included bilateral oophorectomy with or without adjuvant
platinum - based chemotherapy in OC and
EC patients , or concurrent chemo - radiation therapy ( CCRT ) in CC
patients according to the established protocols at the Osaka Medical College Hospital between 2006 and 2008 . -
pubmed
Rif(r )
strains were obtained by in vitro selection of
H. - pubmed
Mineral composition of
urinary calculi from
potbellied pigs with
urolithiasis : 50 cases ( 1982 - 2012 ) . -
pubmed
OBJECTIVE : To determine the mineral composition and anatomic location of
urinary calculi and to investigate sex and reproductive status as predisposing factors for development of
urolithiasis in potbellied
pigs . -
pubmed
DESIGN : Retrospective case series SAMPLES :
Urinary calculi from 50 purebred and crossbred potbellied
pigs . -
pubmed
PROCEDURES : Laboratory records for
urinary calculi of potbellied
pigs submitted to the University of California - Davis Stone Laboratory from 1982 through 2012 were reviewed . -
pubmed
CONCLUSIONS AND CLINICAL RELEVANCE : In contrast to results from studies in commercial
pigs , the most common composition of
urinary calculi identified in
purebred and crossbred
potbellied pigs was amorphous
magnesium calcium phosphate . -
pubmed
Potential predisposing factors for
urolithiasis in
potbellied pigs may be similar to those for
urolithiasis in commercial
pigs . -
pubmed
OBJECTIVES / HYPOTHESIS : To assess the hearing status of
trisomy 21 patients by analyzing electrophysiological and radiological findings of any correlation between
hearing impairment and major or minor
inner ear malformations . -
pubmed
METHODS : A group of 34 ears of
Down syndrome subjects and 20 ears of a
volunteer age- and sex - matched control group of 10 normal
subjects were studied electrophysiologically by means of otoacoustic emissions and auditory brainstem response . -
pubmed
Is
propranolol of benefit in pediatric
burn patients ? -
pubmed
PURPOSE : This study evaluates the incidence trends and clinical outcomes of
children with
hepatocellular carcinoma (
HCC ) and assesses factors predictive of
patient survival . -
pubmed
METHODS : The Surveillance , Epidemiology , and End Results registry was queried from 1973 to 2009 for all
patients between ages 0 and 19 with primary
HCC . -
pubmed
Demographics ,
tumor histology , surgical intervention , and
patient survival were collected . -
pubmed
Fibrolamellar subtype
tumors were exclusive to
children & gt;5years old and exhibited greater survival compared to non - fibrolamellar subtype ( 57 % vs. 28 % , respectively , p=0.002 ) . -
pubmed
Tumor extirpation for
patients with resectable
disease significantly improved overall survival at 5years compared to no surgery ( 60 % vs. 0 % , respectively , p<0.0001 ) . -
pubmed
In this report , we describe an 11 - yr - old kidney transplant recipient
boy who developed immune - mediated
glomerulonephritis with light microscopic , immunofluorescence , and ultrastructural features compatible with acute
PIGN superimposing
chronic PVN , discuss this unusual association and the possible mechanisms of antigen clearance in PVN and present a literature review . -
pubmed
OBJECTIVE : To analyze the clinical characteristics and therapeutics of elderly
patients with
breast carcinomas . -
pubmed
RESULTS : They accounted for 14.6 % ( 312/2137 ) of
breast cancer patients treated during the same period . -
pubmed
Ten
patients who had sustained traumatic
dorsolumbar vertebral fractures with complete
paraplegia were recruited for this study . -
pubmed
RESULTS : The overall
wound infection rate was 12 % , ( 12.2 % for
males and 11.1 % for
females ) . -
pubmed
The overall
wound disruption rate was 6 % , ( 6.1 % for
males and 5.5 % for
females ) and the overall
recurrence rate was 7 % . -
pubmed
Epileptic patients have
intellectual disability and behavioral co - morbidities to the tune of up to 25 and 75 % respectively . -
pubmed
Cognitive impairment seen in
epileptic children include
difficulties in learning , memory , problem solving as well as concept formation . -
pubmed
Investigating a
child with
epilepsy for
cognitive and behavioral impairment is difficult as these tests would require cooperation from the patient 's side to a significant extent . -
pubmed
RESULTS AND DISCUSSION : The identification of factors predictive of
anxiety disorders will possibly allow for effective preventive measures or early treatment interventions , respectively , and reduce the individual
patient 's suffering as well as the overall socioeconomic burden of
anxiety disorders . -
pubmed
The drug has been used successfully to treat
malaria patients in clinical studies , thus validating IspC as an antimalarial target . -
pubmed
Selected prodrugs and parent compounds were also tested for their
cytotoxicity toward
HeLa cells and in vivo in a
Plasmodium berghei malaria model as well as in the
SCID mouse P. - pubmed
This uncertainty has led to inconsistencies in the medical literature and understandable
confusion by clinicians about the appropriate labels for "
M. - pubmed
Pulmonary valve regurgitation was reported in 17.4 % of
patients , and was not related to either successful outcome or balloon size . -
pubmed
Two
patients ( 1.5 % ) developed
restenosis that required repeat BPV . -
pubmed
Prevention of
atherosclerosis by Yindan Xinnaotong capsule combined with swimming in
rats . -
pubmed
The aim of the present study is to evaluate the joint effect of YXC and exercise on
atherosclerosis in
rats . -
pubmed
METHODS : A combined method involving low shear stress and a high - fat diet was used to establish the
atherosclerosis model in
rats . -
pubmed
CONCLUSIONS : In conclusion , this study indicates that the combination of YXC and swimming may prevent
atherosclerosis through a synergistic effect between YXC and swimming in improving blood circulation , hemorheological parameters , blood lipids levels and the vascular endothelium in
rats . -
pubmed
The authors present a
patient who experienced bifrontal
intracranial hemorrhage and
subarachnoid hemorrhage due to a ruptured iatrogenic frontopolar
artery pseudoaneurysm caused during routine endoscopic
sinus surgery . -
pubmed
Seronegative syphilis in a patient co - infected with
HIV . -
pubmed
High - intensity ECC was purposefully selected to maximize the opportunity for
muscle damage and hypertrophic signaling in our novel in vivo
animal model . -
pubmed
Shared decision - making , control preferences and psychological well - being in
patients with
RPE65 deficiency awaiting experimental gene therapy . -
pubmed
The aim of this study was to analyze the psychological aspects of
patients with
RPE65 deficiency awaiting potential enrollment in gene therapy trials . -
pubmed
METHODS : Five
patients with genetically proven
RPE65 deficiency took part in this study . -
pubmed
ent-3beta - Hydroxyatis-16 - ene-2,14 - dione ( 5 ) , 7 and its
aglycon ,
ent-19 - hydroxy - atis-16 - ene-3,14 - dione ( 7a ) , showed significant inhibitory activity on mammosphere formation in
human breast cancer MCF-7 cells at a final concentration of 10 muM. -
pubmed
There were 30
children ( 36 % ) with
injuries of the upper cervical spine , 53 ( 63 % ) with
injuries of the lower cervical spine and 1 patient ( 1 % ) with a combined
injury of upper cervical spine and thoracic spine . -
pubmed
In conclusion , mechanisms and patterns of
injury in children are age related and the majority of the
children had good outcome . -
pubmed
With further advancements and experience , our knowledge in this era of precision medicine will likely lead to strides in improving the quality of life and overall survival of
patients with
BM from
NSCLC . -
pubmed
In
trinitrobenzene - sulfonic acid - induced
colitic rats indicated that
CGA supplementation improved mitochondria ultrastructure and decreased
mitochondrial injury . -
pubmed
Daily intake of diets containing
CGA , such as
coffee and
honeysuckle , may be useful for prevention of
intestinal diseases . -
pubmed
CONCLUSION : Socio - economic factors , educational factors and
human resource factors were found have been associated with childhood
caries gap between the developed and less developed nations . -
pubmed
BACKGROUND :
Children diagnosed with
neurodevelopmental conditions such as
cerebral palsy (
CP ) are at risk of experiencing restrictions in social activities negatively impacting their subsequent social functioning . -
pubmed
in a cohort of
children diagnosed with
cerebral palsy (
CP ) . -
pubmed
The double blind combination of Rituximab by IntraVenous and IntraThecAl injection versus placebo in
patients with
Low - Inflammatory SEcondary progressive MS ( RIVITALISE ; NCT01212094 ) trial was designed to answer : ( 1 ) Whether an induction dose of intravenous and intrathecal rituximab efficiently depletes CNS B cells ? -
pubmed
For a
patient with
renal failure , the treatment of choice is often a simultaneous transplant of the pancreas and kidney or pancreas after kidney . -
pubmed
There is some evidence of benefit with respect to the progression of secondary
diabetic complications in
patients with functioning transplants for several years . -
pubmed
Irregular
uterine bleeding is a major side effect of long - acting
progestogen - only contraceptives in
women , and is the primary reason women discontinue their use . -
pubmed
In this study , a
mouse model of endometrial breakdown was established using a subcutaneous
progesterone implant to understand how
irregular bleeding begins . -
pubmed
The emergence of
metastatic disease in
cancer patients many years or decades after initial successful treatment of primary
tumors is well documented but poorly understood at the molecular level . -
pubmed
Predicting surgical outcome in
patients with
glioblastoma multiforme using pre - operative magnetic resonance imaging : development and preliminary validation of a grading system . -
pubmed
A systematic review of the literature was performed to identify features on pre - operative magnetic resonance imaging ( MRI ) that predict the surgical outcome of
patients with
GBM . -
pubmed
To validate this grading system , a retrospective cohort study of all adult
patients with
supratentorial GBM who underwent surgical resection between the 1 January 2014 and the 31 June 2015 was performed . -
pubmed
Comparative Therapeutic Efficacy of
153Sm - EDTMP and
177Lu - EDTMP for Bone
Pain Palliation in
Patients with Skeletal Metastases :
Patients '
Pain Score Analysis and Personalized Dosimetry . -
pubmed
INTRODUCTION : The aim of the present study was to compare the therapeutic efficacy of
153Sm - EDTMP and
177Lu - EDTMP in
pain palliation in
cancer patients with skeletal
metastases . -
pubmed
MATERIALS AND METHODS : Thirty
patients ( 25 M:5 F , mean age : 66.0 + - 14.7 years ) of
breast / prostate cancer with documented
skeletal metastases were recruited prospectively . -
pubmed
Twenty - two
patients did not have
NVC ( group A ) and 25 had
NVC ( group B ) . -
pubmed
Side effects may occur more frequently in
patients with
NVC at the target coordinate when a root entry zone is used , but the subjective symptoms are not always bothersome . -
pubmed
This study aimed to investigate agreement among professionals on the phenotype of
children with
CP based on standardized videos . -
pubmed
METHODS : In a prospective , observational pilot study , videos of fifteen
CP patients ( 8
boys , mean age 11 + - 5 y ) were rated by three pediatric neurologists , three rehabilitation physicians and three
movement disorder specialists . -
pubmed
Novirhabdoviruses like the
Viral hemorrhagic septicemia virus (
VHSV ) are rhabdoviruses infecting fish . -
pubmed
A recombinant virus derived from a virulent
VHSV strain in which the NV R116 residue has been replaced by a
serine , rVHSVNVR116S , was generated by reverse genetics and used to infect
juvenile trout . -
pubmed
First report of
cutaneous infiltrative lipoma in
goldfish Carassius auratus . -
pubmed
To our knowledge , this is the first report of
cutaneous infiltrative lipoma in
goldfish . -
pubmed
METHODS : A total of 196 male
T2DM patients without medications known to affect bone metabolism or history of
bone fracture , aged & gt;=18years were recruited and divided into
impaired cognition group and normal cognition group . -
pubmed
RBANS total and all indexes scores were also lower in
patients with
impaired cognition ( all P<0.05 ) . -
pubmed
Arthroscopic partial meniscectomy in young
patients with symptomatic
discoid lateral meniscus : an average 10 - year follow - up study . -
pubmed
INTRODUCTION : The aim of this study is to evaluate mid - to - long - term clinical and radiological outcomes after an arthroscopic partial meniscectomy for symptomatic discoid lateral meniscus (
DLM ) in young
patients and to determine whether
degeneration of the residual meniscus and articular cartilage progresses during the follow - up period using magnetic resonance imaging ( MRI ) . -
pubmed
MATERIALS AND METHODS : We retrospectively reviewed
patients aged & lt;= 40 years at surgery who underwent arthroscopic partial meniscectomy for symptomatic
DLM and were followed up for & gt;= 5 years . -
pubmed
CONCLUSIONS : After an arthroscopic partial meniscectomy for symptomatic
DLM , unfavorable clinical outcomes were shown in & gt ; 30 % of the
patients during a mean follow - up of 10.0 years . -
pubmed
Of 4031
patients who underwent IPAA in 1983 - 2014 , 357 developed IPAA - related
pelvic sepsis with or without
anastomotic dehiscence . -
pubmed
Patients with
Crohn ' s disease or
cancer were excluded . -
pubmed
RESULTS : Three hundred and twenty - six
patients developing
pelvic sepsis had diversion at the time of IPAA ( D group ) and in 31 who developed
pelvic sepsis DLI had been omitted ( O group ) . -
pubmed
Forty - eight percent of
patients from the O group with
anastomotic leak underwent reoperation and had a DLI formed at this second procedure versus 12 % in the D group requiring reoperation ( p & lt ; 0.0001 ) . -
pubmed
Latently infected transformed cell models have been used to investigate
HIV latency ; however , these models can not accurately represent the quiescent cellular environment of primary latently infected cells in vivo For this reason , in vivo humanized
murine models have been developed for screening antiviral agents , identifying latently infected T cells , and establishing treatment approaches for
HIV research . -
pubmed
Therefore , in the present study , we used the
HIV - infected hu - NSG
mouse to recapitulate the key aspects of
HIV infection and pathogenesis in vivo Moreover , we evaluated the ability of
HIV - infected
human cells isolated from
HIV - infected hu - NSG
mice on suppressive cART to act as a latent
HIV reservoir . -
pubmed
IMPORTANCE
HIV can establish a stably integrated , nonproductive state of
infection at the level of individual cells , known as
HIV latency , which is considered a primary barrier to curing
HIV . -
pubmed
We therefore describe a novel application of the hematopoietic stem cell - transplanted humanized NSG model for dynamically testing antiretroviral treatment , supporting
HIV infection , establishing
HIV latency in vivo The hu - NSG model could be a facile alternative to humanized bone marrow / liver / thymus or SCID - hu - thy / liv
mice in which laborious surgical manipulation and time - consuming
human cell reconstitution is required . -
pubmed
Materials and Methods : This retrospective study included 48
patients with
lung adenocarcinoma , who underwent a contrast - enhanced dual - energy spectral CT scan before treatment ( 53 GGOs in total ) . -
pubmed
Effects of
Acyclovir and IVIG on Behavioral Outcomes after
HSV1 CNS Infection . -
pubmed
Respirator support time and ICU stay time of
patients in observation group were significantly shorter than those in control group , and the incidence of
postoperative complications of
patients in the observation group were significantly lower than the control group . -
pubmed
Cavernous nerve injury by radiation therapy may potentiate
erectile dysfunction in
rats . -
pubmed
Patients with
malignancy were excluded from the study , except those with suspected stage 1 and 2
endometrial carcinoma . -
pubmed
Of all , 3.3 % of
patients were converted to open surgery ; there was no
vascular injury or re - operation . -
pubmed
Methods : Twenty
patients with
iRBD and 22 healthy controls underwent cervical ( cVEMP ) , masseter ( mVEMP ) and ocular ( oVEMP ) VEMP recording . -
pubmed
Patients were assessed clinically according to presence of motor as well as non - motor symptoms such as
constipation ,
depression , and
hyposmia . -
pubmed
Conclusion : VEMPs unveil consistent and extensive
brainstem abnormalities in
iRBD patients . -
pubmed
Successful use of an immune checkpoint inhibitor in a
patient with
myasthenia gravis in remission . -
pubmed
Inflammation , Immunity , and Vaccine Development for the Gastric Pathogen
Helicobacter pylori . -
pubmed
Clinical trials employing many of the strategies used in rodents for oral immunization including the use of a mucosal adjuvant such as
Escherichia coli LT or delivery by attenuated enteric bacteria have failed to limit
H. - pubmed
Antioxidants protect against
diabetes by improving
glucose homeostasis in
mouse models of inducible
insulin resistance and
obesity . -
pubmed
In healthy
chow - fed
animals as well as in morbidly obese
mice , this
diabetic phase could be reversed within a few weeks . -
pubmed
In ob / ob
mice , antioxidants rescued both
hyperglycaemia and
hyperphagia . -
pubmed
Chikungunya virus (
CHIKV ) , a re - emerging mosquito - borne arbovirus , has caused millions of cases of severe , often chronic
arthralgia during recent outbreaks . -
pubmed
Recent outbreaks have been enhanced by mutations that adapt
CHIKV for more efficient
infection of
Ae . - pubmed
Three weeks after the injections the
rats were exposed to a 7 - day intermittent
hypoxia protocol . -
pubmed
MATERIALS AND METHODS : Eighty
subjects were prospectively enrolled in the study : 35
subjects with clinically confirmed
iNPH and 45 matched healthy controls ( HC ) . -
pubmed
Methods : 120
females aged > = 25 years were evaluated for
acne ,
hirsutism and
androgenetic alopecia . -
pubmed
Results : A 26 - year - old
woman with a past medical history of
obesity ,
prediabetes , and
polycystic ovary syndrome presented with worsening
hirsutism and markedly elevated
testosterone levels . -
pubmed
Given the broad changes in adaptive immunity , including memory T cell expansion , and rising prevalence of
diabetes in the
HIV population , we assessed whether similar relationships were present in persons with HIV (
PWH ) . -
pubmed
Dolutegravir - associated
hyperglycaemia in patients with
HIV . -
pubmed
Approximately 60 % of all
human pathogens and 75 % of emerging
infectious diseases are zoonotic ( of animal origin ) . -
pubmed
In this study , 19 important
zoonotic diseases were reported among Iranian camels including
listeriosis ,
leptospirosis , plague ,
Q fever ,
brucellosis ,
campylobacteriosis ,
tuberculosis ,
pasteurellosis ,
clostridiosis ,
salmonellosis ,
Escherichia coli infections ,
rabies ,
camelpox ,
Middle East respiratory syndrome coronavirus ,
Crimean - Congo haemorrhagic fever ,
echinococcosis ,
cryptosporidiosis ,
toxoplasmosis and
dermatophytosis , most of which belong to bacterial , viral , parasitic and fungal pathogens , respectively . -
pubmed
Results show that
camels are one of the most important sources of
infections and diseases in
human ; therefore , continuous monitoring and inspection programs are necessary to prevent the outbreak of
zoonotic diseases caused by this animal in
humans . -
pubmed
Pneumonia caused by 2019 -
nCoV infection has been reported in Wuhan since December 2019 , and spread rapidly across the country . -
pubmed
Cytomegalovirus Proctitis in a
Patient with
Chronic Lymphocytic Leukemia on
Ibrutinib Therapy : A Case Report . -
pubmed
Subsequent colonoscopy revealed a circumferential rectal
ulcer ; biopsy of the rectal
ulcer was positive for
CMV immunostain . -
pubmed
Baseline prevalence and correlates of
HIV and
HCV infection among people who inject drugs accessing a syringe services program ; Miami , FL . -
pubmed
BACKGROUND :
Blood - borne viral infections , such as
HIV and hepatitis C (
HCV ) , are common
infections among people who inject drugs ( PWID ) . -
pubmed
This study aims to determine the prevalence of
HIV and
HCV infection among PWID accessing the first legal syringe services program ( SSP ) in the state of Florida , along with examining baseline correlates of
HIV and
HCV infection . -
pubmed
Bivariate and multivariable logistic regression models were used to assess correlates of baseline
HCV and
HIV infection independently . -
pubmed
RESULTS : Overall prevalence for
HCV and
HIV infection were 44.4 % and 10.2 % , respectively . -
pubmed
Elevated ICP in two
patients , one related to progressive mass effect from
infarctions , and the other to dialysis , correlated with generalized slowing and attenuation of fast activity up to 24 hours before
clinical deterioration , leading to diffuse suppression . -
pubmed
Two
patients with
intraventricular hemorrhage had cyclic patterns at ~1 per minute and ~6 per minute ( similar frequency to described frequency of Lundberg B and C waves , respectively ) . -
pubmed
METHODS : The prospective observational cohort study was conducted at Bakirkoy Dr. Sadi Konuk Training and Research Hospital , Istanbul , Turkey , from December 1 , 2015,to March 1 , 2016 , and comprised suspected
pneumonia patients aged > 18 years . -
pubmed
Patients in whom
pneumonia was detected in the scan underwent thorax ulstasonography according to Bedside Lung Ultrasound in Emergency protocol . -
pubmed
Patients should be regularly evaluated for
bleeding risks and
thrombotic complications . -
pubmed
Treatments for
inflammatory bowel disease (
IBD ) largely involve lifelong drug prescriptions or surgical intervention that can lead to poor quality of life for
patients . -
pubmed
The introduction of
beta - CD and
PEG /
beta - CD polypseudorotaxane on
SiO2 magnetic nanoparticles ( SOMNP ) limited particle intramuscular dispersion after being injected into
mouse gastrocnemius muscle ( GN ) , which led to the prolonged local
inflammation and
muscle toxicity by CDMNP and
CDMNP - PEG - CD . -
pubmed
A
patient with
cerebral malaria complicated by full - blown
DIC , after failing to respond to other forms of treatment , was successfully treated by exchange transfusion . -
pubmed
Modification of
hepatotoxic effects of
aflatoxin B1 in
rabbits by immunization . -
pubmed
[ Preoperative preparation of
patients with
dysphagia ] . -
pubmed
Fifty - eight continent
women operated on for
genito - urinary prolapse , underwent urethrocystography prior to and 3 months following surgery . -
pubmed
The value of
dobutamine infusion for
thallium myocardial perfusion tomography was assessed in 50
patients with exertional
chest pain undergoing coronary arteriography . -
pubmed
Thirty - nine of 40
patients with
coronary artery disease had a reversible perfusion defect demonstrated by
dobutamine thallium tomography ( sensitivity 97 % ) and 8 of 10
patients with normal coronary arteries had normal myocardial perfusion ( specificity 80 % ) . -
pubmed
Dobutamine infusion was well tolerated in all
patients , including six with
asthma . -
pubmed
Clinical significance of the " palpable mass " in
patients with
muscle - infiltrating bladder cancer undergoing cystectomy after pre - operative radiotherapy . -
pubmed
After a median time of 41 months , 62
patients were alive ; 51 had died from recurrent
bladder cancer and 19 from intercurrent disease without recurrence of their malignancy . -
pubmed
Distant metastases developed in 40
patients , accompanied in 5 cases by local
recurrence . -
pubmed
Local
recurrence was the first sign of
relapse in 11
patients . -
pubmed
In 3
patients the localisation of the
relapse remained unknown . -
pubmed
However , the prognostic value of stage reduction was statistically significant only in
patients with palpable
bladder tumours . -
pubmed
A 13 year old
girl with
PXA in the right occipitoparietal region is reported . -
pubmed
Photochemical damage to the carotid artery of
rats produces microemboli to the brain , resulting in
cavitary lesions resembling lacunes in
humans . -
pubmed
This protein also shows a potent anti - tumour activity in vivo in animal
tumour models and is currently undergoing Phase I
human clinical trials in
cancer patient volunteers . -
pubmed
Release of substance - P - like immunoreactivity in
dog paw lymph after
scalding injury . -
pubmed
Experimental
infection of squirrels
Sciurus vulgaris by
monkey pox virus . -
pubmed
[
Campylobacter pyloridis in
duodenal ulcer ] . -
pubmed
Campylobacter pyloridis (
CP ) were detected in 83 % of the cases by histologic investigation of gastric and duodenal mucosa biopsy specimens obtained from patients with
duodenal ulcers . -
pubmed
Although conventional antiulcer treatment reduces
CP dissemination , the
bacteria are not eliminated in most cases , which might be a cause of
peptic ulcer relapses . -
pubmed
We describe three 14 - year - old
boys who developed
synovial fluid eosinophilia associated with
Lyme disease . -
pubmed
[ Preliminary study on cytogenetics in
patients with
oral lichen planus ] . -
pubmed
Beagle dogs 3 - 7 years old were ovariectomized ( n = 9 ) or sham operated ( n = 6 ) and followed for 48 weeks with measurements of
body weight , tibial shaft bone mineral content ( BMC ) , and serum biochemistry . -
pubmed
10
patients are alive and well 50 - 760 days after transplantation , without any signs of
recurrence and partly without immunosuppressive therapy . -
pubmed
Two
patients died , one due to
relapse of the
leukaemia , and one as a result of
CMV interstitial pneumonia . -
pubmed
Graft versus host disease was seen in 6 of the 12
patients . -
pubmed
The incidence of idiopathic
interstitial pneumonia in our group of
patients was low ( two cases ) . -
pubmed
After removal of all clinically detectable
tumour tissue by maximal surgical therapy in 5
patients , residual systemic
metastases were treated by means of total body irradiation and high - dose
cyclophosphamide , followed by autologous bone marrow transplantation with curative intention . -
pubmed
Relapse occurred in 4
patients between day 100 and 720 after BMT bone marrow transplantation . -
pubmed
Only one
patient remains without sign of
relapse . -
pubmed
Management of simple depressed
skull fractures in
children . -
pubmed
The results showed that
lambs on a low protein diet were less able to withstand the pathogenic effects of
infection with 350
H. - pubmed
[ Modifications by some vasoactive drugs of the effects of an
encephalic ischemic anoxia in
cats ] . -
pubmed
The permissiveness of differentiating
mouse muscle - cell cultures to
infection by group A
coxsackievirus types 1 and 5 . -
pubmed
[ Experimental reproduction of
myocardial infarcts with
arrhythmias in
rabbits ] . -
pubmed
Manual
dilatation of the anus was carried out on 50 unpremedicated
outpatients under
propanidid ,
nitrous oxide , and
halothane anaesthesia with E.C.G.monitoring . -
pubmed
Geometrical
illusions and the response of neurones in the
cat 's visual cortex to angle patterns . -
pubmed
This neural distortion of sensory information seems adequate to explain the well known
illusions of orientation that are associated with
human perception of patterns containing acute angles . -
pubmed
Massive
haemorrhage from vaginal
varicose veins in
patient with
liver cirrhosis . -
pubmed
These levels rose again when the
patient developed
liver metastases but normalized during chemotherapy , never to rise again despite the appearance of cervical lymph node
metastasis . -
pubmed
[ Treatment of
traumatic vitreal hemorrhages in Rh - positive
patients with intravitreal injection of anti - Rh antibodies ] . -
pubmed
In other studies , intravenous administration of
PGI2 ( 25 or 75 ng / kg / min ) ,
indomethacin ( 4 mg / kg ) , or
indomethacin ( 4 mg / kg ) plus
PGI2 ( 25 ng / kg / min ) failed to reverse angiographic delayed
vasospasm produced in vivo in the
canine basilar artery by an intracisternal injection of blood . -
pubmed
The
joint disease in
patients with
erythema nodosum was essentially the same as that seen in patients who did not develop
skin lesions . -
pubmed
A polypeptide which inhibits the growth of
human carcinoma cells has been characterized from Novikoff
rat ascites fluid . -
pubmed
This factor inhibited the anchorage independent growth of the more differentiated
human colon carcinoma cell lines but did not affect the less differentiated
carcinoma cells . -
pubmed
Double - blind comparative clinical trial of
carprofen versus
diclofenac - Na in
patients with
coxarthrosis . -
pubmed
A randomized double - blind trial was performed in 50
patients with moderate to severe
coxarthrosis , 25 receiving 300 mg
carprofen and 25 150 mg
diclofenac - Na daily in 3 doses . -
pubmed
Efficacy of
( E )- 5 -( 2 - bromovinyl )- 2 '- deoxyuridine in the treatment of experimental
herpes simplex virus encephalitis in
mice . -
pubmed
Systemic treatment of
mice with
( E )- 5 -( 2 - bromovinyl )- 2 '- deoxyuridine (
BVDU ) showed a significant therapeutic efficacy against
herpes simplex type 1 virus ( HSV-1 ) encephalitis . -
pubmed
Furthermore , at doses of 300 - 500 mg / kg per day
BVDU prevented the establishment of latent
virus infection in the trigeminal ganglia following intracerebral
HSV-1 inoculation . -
pubmed
A
patient who had
MF with ulcerating cutaneous nodules is presented herein . -
pubmed
Transgenic
mouse models in studies of
skeletal disorders . -
pubmed
Studies of mutations in
mice and
humans are identifying molecular defects in a number of
osteochondrodysplasias . -
pubmed
High frequency of
thyroid dysfunction in
patients with
vitiligo . -
pubmed
This study was undertaken to determine the frequency and type of
thyroid disease in 35 consecutive
patients admitted because of
vitiligo compared with a matched control group . -
pubmed
One or more signs of
thyroid disease was demonstrated in 15 out of 35
patients ( 43 % ) with
vitiligo , as compared to 7 out of 35 ( 20 % ) in the matched control group ( p = 0.04 ) . -
pubmed
Thyroid dysfunction - 6
patients with
hyperthyroidism and 2 with
hypothyroidism - was found in 8 out of 35
patients , as compared to no patient in the control group ( p = 0.003 ) . -
pubmed
There appears to be an increased frequency of clinical as well as subclinical
thyroid disease in
patients with
vitiligo . -
pubmed
Our findings support the theory of
vitiligo being an
autoimmune disease and indicate a need for screening
vitiligo patients for
thyroid disease . -
pubmed
Three
patients with
S - I radiculopathy leading to ipsilateral
neurogenic calf hypertrophy following
hernia nuclei pulposi are described , two
men of 79 and 78 years old and a
woman of 46 years . -
pubmed
We investigated
weight gain and clinical course of 14
patients with
cystic fibrosis (
CF ) , aged 7 to 23 years , who received long - term nocturnal supplemental feedings by means of percutaneous endoscopic gastrostomies ( PEGs ) . -
pubmed
We conclude that nocturnal
PEG feedings of malnourished
patients with
CF improve nutritional status and lung function without major side effects . -
pubmed
This study has concluded that TNP can be used for spinal cord monitoring , especially in
patients with
thoracolumbar disorders . -
pubmed
In a randomized 6 - week trial comparing
fluoxetine with placebo , the Medical Outcomes Study 36 - Item Short - Form Health Status Survey ( SF-36 ) scales were used to measure the effects of treatment on functional health and well - being among elderly ( age & gt ; or = 60 years )
outpatients with
major depression . -
pubmed
Compared with national norms for individuals over age 60 , study
patients before treatment exhibited baseline decrements on the following SF-36 scales : mental health , role limitations due to emotional problems , social functioning , vitality , role limitations due to physical problems , and
bodily pain . -
pubmed
Nosocomial septicemias due to
methicillin - resistant
staphylococcus aureus and
Pseudomonas aeruginosa in a university hospital over a 12 - year period -- the same intractable
infections . -
pubmed
Clinical features of nosocomial
bacteremias due to
methicillin - resistant
Staphylococcus aureus (
MRSA ) ( M group , n = 71 ) and
Pseudomonas aeruginosa ( P group , n = 25 ) in a university hospital during 1982 - 1993 were retrospectively analyzed . -
pubmed
We studied 105
subjects who fulfilled the DSM - III - R criteria for a current major
depressive episode and 41
volunteers with no current
mental disorder . -
pubmed
The relationship between these two variables and treatment outcome was particularly strong in
depressed male subjects who were receiving
desipramine , for whom they accounted for 36 % of the variance in treatment outcome . -
pubmed
Although this finding requires replication , it is consistent with other reports of the usefulness of thyroid - axis indices measured at different times of day in
depressed patients . -
pubmed
We reported a 71 - year - old male
patient with multiple liver
recurrence of
hepatocellular carcinoma , who responded to arterial infusion chemotherapy using
CDDP and 5 - FU . -
pubmed
[ The dynamic laboratory indices of
patients with
insulin - dependent diabetes mellitus during health - resort treatment ] . -
pubmed
The immunological status was assessed in 100
patients with
insulin - dependent diabetes mellitus before and after treatment in sanatorium . -
pubmed
Canine cystine urolithiasis . -
pubmed
In some
dogs , the severity of
cystinuria may decline with advancing age . -
pubmed
OBJECTIVE : In
patients with severe
aortic stenosis , we studied the impact of gender on preoperative left ventricular geometry and function , as well as on early postoperative mortality and morbidity . -
pubmed
RESULTS : The
patients had severe
aortic stenosis and the mean pressure gradients were similar in females and males . -
pubmed
The ejection fraction was similar in females ( 55+/-14 % ) and males ( 55+/-13 % ) , and
patients of both sexes had significantly lower
stroke volume and cardiac index than healthy controls . -
pubmed
The
eczema in 3 of 4
patients who stopped smoking improved . -
pubmed
This study evaluates postoperative
patient comfort and satisfaction of 100 unilateral
inguinal hernia repairs performed by Shouldice procedure with steel wire and local anesthesia . -
pubmed
Only 7 of 61 ( 11.5 % )
patients had
ketoacidosis at first presentation . -
pubmed
Five
patients had associated
autoimmune thyroid disease and 10 ( 16.7 % ) patients had family history of
diabetes in first - degree relatives . -
pubmed
Movement related cortical source for elbow flexion in
patients with
branchial plexus injury after intercostal - musculocutaneous nerve crossing . -
pubmed
Nine
patients with
brachial plexus injury whose transected musculo - cutaneous nerves had been sutured with intercostal nerves were examined and the relationship between flexion of the operated elbow and the respiratory movement were shown . -
pubmed
It is anticipated that future research in these areas will identify optimal treatment strategies for elderly
ESRD patients starting on dialysis and improve
patient outcomes . -
pubmed
Antidepressants are not only effective in younger
adults but also in older persons with
depression . -
pubmed
Such findings may also explain the observed high clinical incidence of
vascular calcification in the
osteoporotic patient population . -
pubmed
Effect of
Withania somnifera on
20 - methylcholanthrene induced
fibrosarcoma . -
pubmed
Administration of an extract from the root of the plant
Withania somnifera ( 20mg / dose / animal i.p ) was found to inhibit the
20 - methylcholanthrene induced
sarcoma development in
mice and increase the life span of
tumour bearing animals . -
pubmed
Withania could increase the
GSH level ( 7.7 micromoles / mg protein ) which was lowered in control
tumour bearing
animals ( 3.96 micromoles / mg protein ) . -
pubmed
All the
animals in the control group developed
sarcoma by the 80th day of carcinogen administration . -
pubmed
Only 3
animals in the
Withania treated group developed
sarcoma by the 105th day . -
pubmed
These results indicate that
Withania could inhibit
20 - methylcholanthrene induced
sarcoma development in
mice . -
pubmed
[ The effects of percutaneous endoscopic gastrostomy feeding in
patients with
swallowing disturbance ] . -
pubmed
I conclude that
PEG will become the first choice for improving nutrition in
patients with
dysphasia and will contribute to continuous enteral nutrition for home care . -
pubmed
Immunohistochemically we examined
normal - appearing intranodal thyroid tissue in four
patients who did not show evidence of
papillary carcinoma histologically or clinically . -
pubmed
[
Autonomic neuropathy in
uremic patients ] . -
pubmed
In
patients with
intermittent claudication , the
phosphorus -
creatinine index at peak of exercise was decreased by 26.1 % ( p & lt ; 0.001 ) , in
patients with
varicose disease -- by 25.6 % ( p & lt ; 0.001 ) , in
patients with chronic
heart failure by 8 % ( p & lt ; 0.001 ) . -
pubmed
This article reviews the diagnosis and management of clinical
disorders of potassium balance , with particular attention to the
critically ill patient . -
pubmed
[ Changes of
HBV - DNA in patients with
chronic hepatitis B -- relation to prognosis and therapy ] . -
pubmed
STUDY DESIGN : During a 22 - year period ( July 1979 - June 2001 ) , nipple discharge from nine
males with
breast lesions were examined . -
pubmed
RESULTS : In the three
patients with florid
gynecomastia the smears were cellular , with numerous benign ductal cells and papillary fragments along with foam cells and inflammatory cells . -
pubmed
PURPOSE : Randomized trials in
fluorouracil ( FU)-refractory
colorectal cancer demonstrate significant survival advantages for
patients receiving
irinotecan . -
pubmed
Grade 3/4
diarrhea occurred in 36 % of
patients treated weekly and in 19 % of those treated once every 3 weeks ( P = .002 ) . -
pubmed
Grade 3/4
neutropenia occurred in 29 % of
patients treated weekly and 34 % of those treated once every 3 weeks ( P = .35 ) . -
pubmed
CONCLUSION :
Irinotecan schedules of weekly and of once every 3 weeks demonstrated similar efficacy and quality of life in
patients with FU - refractory , metastatic
colorectal cancer . -
pubmed
The authors analyzed reports from randomized controlled trials to compare suicide rates among
depressed patients assigned to an SSRI , other antidepressants , or placebo . -
pubmed
RESULTS : Of 48,277
depressed patients participating in the trials , 77 committed suicide . -
pubmed
A bioassay of the
phenylurea herbicide
fluometuron for possible
carcinogenicity was conducted by administering the test chemical in feed to
F344 rats and
B6C3F1 mice . -
pubmed
Splenomegaly observed in
rats in the subchronic studies influenced selection of the doses for the chronic study ; however , no splenic effects were observed in the chronic study . -
pubmed
Mean
body weights of the dosed groups of male and female
rats and
mice were essentially the same as those of the corresponding control groups . -
pubmed
Similarities between mean
body weights and survival between dosed and control animals in thechronic study suggest that these
animals could have tolerated higher doses . -
pubmed
Incidences of
hepatocellular carcinomas or
adenomas in
male mice were dose related , and the incidence in the high - dose group was marginally higher than that in the corresponding matched controls or pooled controls from concurrent studies . -
pubmed
Equivocal results were obtained for male
B6C3F1 mice which may have had an increased incidence of
hepatocellular tumors . -
pubmed
Because of the equivocal findings and because both
rats and
mice may have been able to tolerate higher doses , it is concluded that additional testing of
fluometuron for
carcinogenicity is warranted . -
pubmed
We report a case of a
boy aged 3 years and 1 month with a history of
oral thrush ,
chronic diarrhea ,
skin abscesses , multiple small joints
osteomyelitis , and multiple
liver abscesses since 2 months of age . -
pubmed
Two episodes of
aspergillosis with severe
aspergillus lung empyema and life - threatening
Klebsiella pneumoniae infections were noted in the first 2 years of life despite long - term prophylaxis with
trimethoprim - sulfamethoxazole and
itraconazole . -
pubmed
Patients in
leg ulcer services with
leg ulceration were screened for inclusion in this trial . -
pubmed
Patients with
arterial disease ( ankle brachial pressure index & lt ; 0.8 ) and causes of
ulceration other than
venous disease were excluded . -
pubmed
For
patients with
bilateral ulceration , the limb with the larger area of
ulceration was studied . -
pubmed
In all , 156
patients met entry criteria and were randomized from the 12 clinical centers with median ( range )
ulcer size of 4.33 ( 0.33 - 123.10 ) cm(2 ) . -
pubmed
Of the 74
patients randomized to the four - layer bandage , 51(69 % ) had
ulcer closure on treatment compared with 60/82 ( 73 % ) on the cohesive short - stretch system . -
pubmed
The
tumor locations were in the uncinate process in 4 ( 40 % ) , in the head and neck in 2 ( 20 % ) , in the body in 1 ( 10 % ) , and in the tail in 3 ( 30 % )
patients . -
pubmed
During dynamic CT in 8
patients , 6
tumors showed early arterial ( EA ) enhancement and persisted into the portal venous ( PV ) phase , whereas the other 2
tumors revealed enhancement in the EA phase and washout in PV phase . -
pubmed
The complexity of the diagnostics of this disease makes it necessary to search for new methods ; for this reason immunity in
CFA patients must be studied . -
pubmed
This made it possible to propose to use these reactions for confirming the diagnosis of
CFA and suggested the probable role of
M. - pubmed
Six
patients with established
nonunion of the humeral shaft underwent this technique . -
pubmed
Bilateral
retinal detachment was present in 12 ( 10.8 % ) ; 51 ( 46 % )
patients had some form of bilateral ocular pathology at initial presentation . -
pubmed
CASE : This 30 - year - old
woman had an
accessory ovarian tumor attached to the infundibulum of the right fallopian tube which was solid and gross pathologically and microscopically showed the appearances of
steroid cell tumor ,
NOS , a benign entity . -
pubmed
[ Phototactic behavior of
Daphnia carinata as an indicator of
chromium biotoxicity ] . -
pubmed
The study on the phototactic behavior of
Daphnia carinata clone Dc42 as an indicator of
chromium biotoxicity showed that the phototaxis inhibition ratio ( Rpi ) of
D. - pubmed
METHODS : Corneal asphericity and r(o ) were calculated by using corneal topography data on 643
children ( 72 myopes , 370 emmetropes , and 201 hyperopes ) , ages 6 to 15 years , who participated in the Orinda Longitudinal Study of
Myopia ( OLSM ) during 1991 . -
pubmed
Relationship between
creatinine clearance and plasma
homocysteine levels in predialytic
chronic renal failure patients . -
pubmed
BACKGROUND :
Trichobezoars represent 55 % of
human bezoars . -
pubmed
OBJECTIVE : To study the clinical features , diagnostic methodology and treatment in
patients with
trichobezoars . -
pubmed
RESULTS : All
patients had an
epigastric mass ,
dyspepsia ,
vomiting , and
weight loss of 5 to 25 kg , without
pain . -
pubmed
A
gadolinium - enhanced " one - stop shop '' magnetic resonance angiography was performed within 24 hours of completed diagnostic imaging work - up for
pulmonary embolism and
deep venous thrombosis in 20
patients . -
pubmed
The " one - stop shop '' imaging procedure using
gadolinium - enhanced magnetic resonance angiography was feasible and proved to offer a reliable and rapid diagnostic approach in
thromboembolic disease , sparing
patients ' exposure to ionizing radiation and iodinated contrast media . -
pubmed
Probability of axillary lymph node
metastasis when sentinel lymph node biopsy is negative in
women with clinically node negative
breast cancer : a Bayesian approach . -
pubmed
METHODS :
Patients admitted with
West syndrome in
Children 's Hospital , Islamabad , between January 1995 and December 2001 were included in the analysis . -
pubmed
Seventy - two
patients were given oral
prednisolone , 51 responded and 17 remained
spasms free after oral
steroids were stopped . -
pubmed
We report the response to pacing and pharmacologic maneuvers performed in
patients with stable focal
ATs after segmental PV isolation . -
pubmed
METHODS :
Patients with persistent left
AT after cessation of antiarrhythmic drug therapy presented for mapping and ablation . -
pubmed
RESULTS : Five
patients ( 3
men and 2
women ; age 65 + /- 10 years ) had focal left
AT that persisted in response to pacing maneuvers . -
pubmed
Four
patients had
ATs ( cycle length 265 + /- 18 ms ) that demonstrated focal areas of early activation at the septal aspect of the right lower ( 3
patients ) or right upper ( 1 patient ) PV ostium . -
pubmed
Adenosine was infused with transient
AV block and no change to the
tachycardia cycle length in three
patients . -
pubmed
METHODS : Fifty - four
breast cancer patients with 57
breast lesions underwent 2 sequential PET scans ( dual - time - point imaging ) . -
pubmed
In this study , the possible involvement of these two hormones in
B - deficiency - induced changes in apical dominance was investigated by applying B or the synthetic
CK CPPU to the shoot apex of
pea plants grown in nutrient solution without B supply . -
pubmed
METHODS : Secondary analyses of three randomized , double - blind , placebo - controlled multicenter studies in stage 3 and 4
chronic kidney disease (
CKD )
patients with
SHPT were performed to compare three times per week ( TIW ) with QD dosing of
paricalcitol . -
pubmed
In
CKD patients , baseline data were similar between the TIW studies ( n = 72 ,
paricalcitol ; n = 73 , placebo ) and QD studies ( n = 35 ,
paricalcitol ; n = 40 , placebo ) . -
pubmed
BACKGROUND AND PURPOSE : To determine the sleep response to
caffeine in
individuals vulnerable to stress - related
sleep disturbance as measured by polysomnography . -
pubmed
PATIENTS AND METHODS : Eleven healthy
individuals without
insomnia scoring low ( 4
women , mean age=32.64+/-15.46 years ) and 10 healthy
individuals also without
insomnia scoring high ( 6
women , mean age=34.20+/-13.73 years ) on a measure of vulnerability to stress - related
sleep disturbance were studied in a laboratory protocol . -
pubmed
Importantly ,
individuals reporting vulnerability to stress - related
sleep disturbance had significantly prolonged latency to persistent sleep in response to the
caffeine challenge ( interaction ; P<0.05 ) . -
pubmed
This finding provides further support for generalized trait vulnerability by demonstrating a
sleep disturbance to a wake - promoting pharmacological challenge in specific a priori identified
individuals . -
pubmed
Use of
selamectin for the treatment of
psoroptic and sarcoptic mite infestation in
rabbits . -
pubmed
A total of 42
New Zealand rabbits with psoroptic
mange and 37
Angora rabbits with
sarcoptic mange were used in the present study . -
pubmed
We present foreign body
granulomas induced by activated charcoal from intraperitoneal chemotherapy and mimicked peritoneal metastases in the
patients with
gastric cancer . -
pubmed
BACKGROUND : The mechanism underlying nocturnal
sudden death in
patients with
MSA remains unclear . -
pubmed
Fiberoptic laryngoscopy during wakefulness showed that 3 ( 14 % ) of the 21
patients exhibited
vocal cord abductor paralysis , and laryngoscopy under anesthesia showed that 9 ( 45 % ) of 20
patients exhibited vocal cord abductor
paralysis . -
pubmed
Laryngoscopy under anesthesia also revealed that 11 ( 55 % ) of 20
patients showed
upper airway obstruction in places other than the vocal cords , including obstruction at the base of the tongue or soft palate . -
pubmed
CONCLUSIONS : We observed daytime
hypoxemia with an increased alveolar - arterial
oxygen gradient , Cheyne - Stokes respiration , and novel
abnormal laryngopharyngeal movements in
patients with
MSA . -
pubmed
Complete clinical and virological remission of refractory
HIV - related
Kaposi ' s sarcoma with
pegylated interferon alpha . -
pubmed
Improved survival for
children with
parameningeal rhabdomyosarcoma : results from the AIEOP
soft tissue sarcoma committee . -
pubmed
PROCEDURE : We reviewed 109
children with non - metastatic PM -
RMS enrolled in the Italian RMS79 , RMS88 and RMS96 protocols over a 24 - year period . -
pubmed
CONCLUSION : Outcome in PM -
RMS patients enrolled in three consecutive Italian protocols has progressively improved , as a result of intensive chemotherapy , delayed surgery and , possibly , HART , though improved imaging and radiotherapeutic tools may have had a role as well . -
pubmed
Streptococcus intermedius is found in biofilms on teeth and as a commensal member of the gastrointestinal and urinary floras , but may also be associated with deep - seated
purulent infections and
infective endocarditis . -
pubmed
The obtained data allow us to suppose that the development of oxidative stress under
demyelination conditions is a result of strong
metabolic disorders and decrease of antioxidant defence in the
patients during the disease development . -
pubmed
The necessity of individual approaches for antioxidant therapy of
patients with
MS is discussed . -
pubmed
Continuous oral or intramuscular
medroxyprogesterone acetate versus the
levonorgestrel releasing intrauterine system in the treatment of
perimenopausal menorrhagia : a randomized , prospective , controlled clinical trial in female
smokers . -
pubmed
DESIGN : One hundred thirty - two
women with
menorrhagia were included in this prospective , randomized , comparative trial . -
pubmed
An
avipoxvirus infection in a
goshawk (
Accipiter gentilis ) . -
pubmed
This report describes the
nodular lesions found on a young , male
European goshawk (
Accipiter gentilis ) which were found to be
poxvirus lesions in conjunction with a
Staphylococcus aureus infection . -
pubmed
To our knowledge the
goshawk has been reported as being susceptible to
avipoxvirus infections , but no clinical reports have been published concerning this species . -
pubmed
Regional endocardial left atrial voltage and electrogram fractionation in
patients with
atrial fibrillation . -
pubmed
This study aimed at investigating endocardial voltage in different regions of the left atrium in
patients with
atrial fibrillation (
AF ) . -
pubmed
METHODS AND RESULTS : Thirty - six
patients ( aged 56 + /- 7 years , 10
female ) scheduled for circumferential ablation for paroxysmal
AF were studied . -
pubmed
CONCLUSION : During
AF , the posterior wall displays significantly higher voltage and electrogram fractionation compared with other parts of the left atrial endocardium outside the antra of both pulmonary veins in
patients with paroxysmal
AF . -
pubmed
[ Characteristics of postoperative ectopic junctional ectopic
tachycardia in
children with
congenital heart disease ] . -
pubmed
BACKGROUND : As more
patients undergo diagnostic thyroid surgery , the development of posthemithyroidectomy
hypothyroidism is becoming a major concern . -
pubmed
RESULTS : Biochemical
hypothyroidism developed in 37
patients ( 36.6 % ) . -
pubmed
A
patient with chronic hemodialysis - dependent
end - stage renal disease presenting with mild
dyspnea on exertion and a harsh
systolic murmur . -
pubmed
The unilateral
ischemia hindlimb model was made with 12 Lewis
rats . -
pubmed
Cardiovascular disease is a leading cause of
death in the United States and across the world , and better therapies are constantly being sought to improve
patient outcomes . -
pubmed
,
diabetes , lipid management , and weight control ) , but it also has been shown in
animal studies to have positive cardiac effects irrespective of its effects on
glucose control and
weight loss . -
pubmed
Chondrocyte
death and cartilage degradation after autologous osteochondral transplantation surgery in a
rabbit model . -
pubmed
Novel therapeutic strategies targeting vascular redox in
human atherosclerosis . -
pubmed
RADAR - A randomised , multi - centre , prospective study comparing best medical treatment versus best medical treatment plus renal artery stenting in
patients with haemodynamically relevant
atherosclerotic renal artery stenosis . -
pubmed
BACKGROUND : Prospective , international , multi - centre , randomised ( 1:1 ) trial to evaluate the clinical impact of percutaneous transluminal renal artery stenting ( PTRAS ) on the
impaired renal function measured by the estimated
glomerular filtration rate ( eGFR ) in
patients with haemodynamically significant
atherosclerotic renal artery stenosis . -
pubmed
Biopsy - proven
prostatic malignancy was detected in 20
patients . -
pubmed
Using recombinant
tetanus toxin H(C ) fragment ( rTT - H(C ) ) as carrier , we prepared multimeric bivalent immunogens featuring the synthetic
hexasaccharide fragment of O - PS of
Vibrio cholerae O:1 , serotype Ogawa , in combination with either the synthetic
hexasaccharide fragment of O - PS of
Vibrio cholerae O:1 , serotype Inaba , or a synthetic
disaccharide tetrapeptide peptidoglycan fragment as adjuvant . -
pubmed
[
Bilateral cerebellopontine angle lipoma in an asymptomatic
patient : a case report ] . -
pubmed
MATERIAL AND METHODS : 22
patients with
intellectual disability ,
congenital anomalies and
dysmorphic features were analysed . -
pubmed
Effect of prophylactic trochanteric epiphyseodesis in older
children with
Perthes ' disease . -
pubmed
To evaluate the effect of prophylactic epiphyseodesis of the greater trochanter in
Perthes ' disease , 62
children with
unilateral Perthes ' disease who underwent trochanteric epiphyseodesis combined with varus osteotomy of the femur during the active stage of the disease ( mean age at surgery : 8.4 y ) and 20 controls were followed up until skeletal maturity . -
pubmed
In the
infection - induced cells , viral RNA was degraded rapidly , and a cytosol extract prepared from the infected cells showed RNA degradation activity specific for
ToMV- or GFP - related sequences . -
pubmed
The inducible
virus infection system may provide a method for biochemical analysis of antiviral RNA silencing and silencing suppression by
ToMV . -
pubmed
A / C magnetic
hyperthermia of
melanoma mediated by
iron ( 0 )/ iron oxide core / shell magnetic nanoparticles : a
mouse study . -
pubmed
Aim of the study was assessment of prevalence of
HPS in cirrhotic
patients qualified to liver transplantation and determination of clinical risk factors of this
syndrome . -
pubmed
MATERIAL AND METHODS : The study involved 30
patients with advanced
liver cirrhosis of different etiology , qualified to liver transplantation . -
pubmed
RESULTS : We did not find symptomatic
HPS in the investigated group , but 2
patients ( 6.6 % ) with
alcoholic cirrhosis showed arterio - venous intrapulmonary shunt . -
pubmed
In a randomized , double - blind , placebo - controlled , multinational trial in
patients with locally advanced or
metastatic renal cell carcinoma , the median progression - free survival ( PFS ) of
patients who were treated with
pazopanib 800 mg once daily was significantly longer than that of placebo
recipients ( 9.2 vs 4.2 months ; hazard ratio 0.46 [ 95 % CI 0.34 , 0.62 ] ) . -
pubmed
Oral
pazopanib had an acceptable tolerability profile in
patients with advanced
renal cell carcinoma . -
pubmed
This opinion piece explores an " ablate and wait " strategy for improving the 5 - year
recurrence - free outcome of liver transplantation in
patients with
hepatocellular carcinoma . -
pubmed
Simple non - invasive
fibrosis scoring systems can reliably exclude advanced
fibrosis in
patients with
non - alcoholic fatty liver disease . -
pubmed
BACKGROUND : Accurate evaluation of
liver fibrosis in
patients with
non - alcoholic fatty liver disease (
NAFLD ) is important to identify
patients who may develop complications . -
pubmed
The aim of this study was to compare the diagnostic performance of simple non - invasive tests in identifying advanced
fibrosis among
patients with biopsy - proven
NAFLD . -
pubmed
METHODS : Consecutive
patients with biopsy proven
NAFLD were recruited from the Newcastle Hospitals Fatty Liver Clinic from 2003 to 2009 . -
pubmed
93
patients ( 64 % ) had
non - alcoholic steatohepatitis . -
pubmed
METHODS : We describe a case of a 28 - year - old
male who presented with intractable
binocular diplopia , which was relieved with a corneal tattoo . -
pubmed
Specific mechanical
pain hypersensitivity over peripheral nerve trunks in
women with either
unilateral epicondylalgia or
carpal tunnel syndrome . -
pubmed
OBJECTIVE : To investigate if pressure
pain sensitivity is related to specific nerve trunks in the upper extremity of
patients with either
unilateral lateral epicondylalgia (
LE ) or
carpal tunnel syndrome (
CTS ) . -
pubmed
BACKGROUND : In the clinical setting ,
patients with
LE tend to exhibit
radial nerve trunk tenderness , whereas
patients with
CTS exhibit median nerve
tenderness . -
pubmed
METHODS : Sixteen
women with unilateral
LE ( mean+-SD age , 43 + -7 years ) , 17
women with unilateral
CTS ( 43 + -6 years ) , and 17 healthy
women ( 43 + -6 years ) were included in this study . -
pubmed
Additionally , radial ( P<.001 ) and ulnar ( P=.005 ) nerves were more sensitive bilaterally in
patients with
LE than in
patients with
CTS . -
pubmed
The median nerve was more sensitive bilaterally in
patients with
CTS than
patients with
LE ( P=.002 ) . -
pubmed
CONCLUSIONS : Bilateral mechanical nerve
pain hypersensitivity is related to specific and particular nerve trunks in
women with either unilateral
LE or
CTS . -
pubmed
Our results suggest the presence of central and peripheral sensitization mechanisms in
individuals with either
LE or
CTS . -
pubmed
Identifying neurobiological predictors of response to antipsychotics in
patients with
schizophrenia is a critical goal of translational psychiatry . -
pubmed
In this study , we sought to identify magnetic resonance ( MR ) imaging measures of the brain that predict treatment response in
patients experiencing a first - episode of
schizophrenia . -
pubmed
Structural MR imaging scans were acquired in 39
patients experiencing a first - episode of
schizophrenia with minimal or no prior exposure to antipsychotics participating in a double - blind 16 - week clinical trial comparing the efficacy of
risperidone vs
olanzapine . -
pubmed
Our findings are consistent with the hypothesis that plasticity and cortical thickness may be more preserved in responders and that MR imaging may assist in the prediction of antipsychotic drug response in
patients experiencing a first - episode of
schizophrenia . -
pubmed
Affected
patients are susceptible to severe , life - threatening
bacterial and fungal infections and
excessive inflammation characterized by
granulomatous enteritis resembling
Crohn ' s disease and
genitourinary obstruction . -
pubmed
[ Continuous positive airway pressure treatment in sleep - related
respiratory disorders in
children ] . -
pubmed
Continuous positive airway pressure ( CPAP ) is the first choice in the treatment of
apnea - hypopnea syndrome in adults and , in recent years , is considered the second option after surgery in
children . -
pubmed
Oleanolic acid inhibits
hypertrophic scarring in the
rabbit ear model . -
pubmed
METHODS : A
rabbit ear model of
hypertrophic scarring was used , with
wounds produced with a biopsy punch . -
pubmed
RESULTS : Treatment with different concentrations of
oleanolic acid ( OA ) for 22 days significantly inhibited
hypertrophic scarring in
rabbit ear tissue . -
pubmed
CONCLUSIONS : OA suppresses
hypertrophic scarring in the
rabbit ear model and may be an effective cure for
human hypertrophic scarring . -
pubmed
Data for the acute and chronic excess
toxicity of
anilines and other ' polar narcotics ' for
D. - pubmed
CASE REPORT : An 87 - year - old
woman presented with a four - month history of left - sided
otorrhoea and
otalgia . -
pubmed
What is the best criterion for the interpretation of adrenal vein sample results in
patients with
primary hyperaldosteronism ? -
pubmed
BACKGROUND : In
patients with
primary hyperaldosteronism , adrenal vein sampling ( AVS ) has emerged as a gold standard for distinguishing between unilateral and bilateral disease , but multiple criteria have been used and no consensus exists as to the most accurate criterion . -
pubmed
METHODS : This is a retrospective analysis of AVS results in 108
patients with
primary hyperaldosteronism treated at a single institution . -
pubmed
pGFPshIGF-1R was delivered into
A549 cells in vitro and injected intravenously into the
tumor - bearing
mice every 48 h for four doses in vivo by way of lipofection or magnetofection . -
pubmed
At Week 3 after the 4th injection , the
mice were sacrificed and the
tumors removed and weighed . -
pubmed
RS extends lifespan in
obese rats . -
pubmed
A 56 - year - old
man had left nephrectomy and resection of a
cavoatrial tumor thrombus under a cardiopulmonary bypass assist for
left renal cell carcinoma . -
pubmed
Our experience with endoscopic sphenopalatine artery ligation for four
patients with posterior
existaxis is described . -
pubmed
All
patients had
epistaxis refractory to anterior and posterior nasal packing , which was rapidly controlled following the procedure . -
pubmed
PURPOSE : Many
dry eye ( DE )
patients are sensitive to adverse environments where tear evaporation rate ( TER ) increases . -
pubmed
Influenza viruses are respiratory pathogens that continue to pose a significantly high risk of morbidity and mortality of
humans worldwide . -
pubmed
Patients sustaining
PE and severe
blebitis following trabeculectomy or a combined trabeculectomy with a
cataract extraction procedure performed from 1990 through 2008 and diagnosed from 1990 through 2012 were recorded at St Erik Eye Hospital . -
pubmed
DB844 (
CPD-594 - 12 ) ,
N - methoxy-6 -{ 5 -[ 4 -( N - methoxyamidino ) phenyl ]- furan-2 - yl }- nicotinamidine , is an oral prodrug that has shown promising efficacy in both
mouse and
monkey models of second stage
human African
trypanosomiasis . -
pubmed
However ,
gastrointestinal ( GI ) toxicity was observed with high doses in a
vervet monkey safety study . -
pubmed
METHODS : In all , 16 hospitalized
patients ( 27.1 + - 11.3 years ) with moderate / severe
TBI wore actigraphs for 10 days , starting in the intensive care unit ( ICU ) when continuous sedation was discontinued and
patients had reached medical stability . -
pubmed
Predicting chemotherapy
toxicity in older
adults with
lung cancer . -
pubmed
OBJECTIVE : Existing oncology performance status measurements are used to predict chemotherapy
toxicity in all
patients with
cancer , regardless of age . -
pubmed
We investigated whether this tool can usefully characterize chemotherapy risks for older
patients with
lung cancer . -
pubmed
METHODS :
Patients from our hospital aged & gt;= 65 years with
lung cancer completed a questionnaire form prior to chemotherapy . -
pubmed
RESULTS : Between September 2011 and September 2012 , 120
patients with
lung cancer ( 87
males and 33 females ) & gt;= 65 years of age ( mean : 69 years ; range : 65 - 82 years ) were enrolled in the study . -
pubmed
CONCLUSION : This new CARG
toxicity tool can be used to better distinguish the risks of chemotherapy
toxicity than the KPS for older
patients with
lung cancer , and may change the standards for oncology assessments . -
pubmed
Cardiac arrest due to left circumflex
coronary artery embolism as a complication of subtherapeutic oral anticoagulation in a
patient with mitral and aortic mechanical valve prostheses . -
pubmed
We report a case of a 65 - year - old female
patient after replacement of aortic and mitral valve with mechanical prostheses and implantation of a pacemaker hospitalized in our clinic due to
acute coronary syndrome complicated with
cardiac arrest due to
ventricular fibrillation . -
pubmed
In spite of their proven efficacy in the prevention of
ischaemic stroke related to
atrial fibrillation and prevention or treatment of
deep vein thrombosis and
pulmonary embolism , the use of new oral anticoagulants for the treatment of
patients with mechanical valve prostheses needs further research . -
pubmed
This exciting development , coupled with ongoing clinical trials of a range of other novel compounds , is bringing hope to
patients and their clinicians and raises the prospect that , in the future , it may become possible to successfully arrest the development of progressive scarring in
IPF . -
pubmed
Treadmill exercise ameliorates symptoms of
attention deficit / hyperactivity disorder through reducing Purkinje cell loss and astrocytic reaction in spontaneous
hypertensive rats . -
pubmed
We investigated the effects of treadmill exercise on Purkinje cell and astrocytic reaction in the cerebellum of the
ADHD rat . -
pubmed
Adult male spontaneously
hypertensive rats ( SHR ) and
Wistar - Kyoto rats ( WKYR ) weighing 210 + - 10 g were used . -
pubmed
The
animals were randomly divided into four groups ( n= 15 ): control group ,
ADHD group ,
ADHD and
methylphenidate (
MPH)-treated group ,
ADHD and treadmill exercise group . -
pubmed
We analysed the outcomes of management of 1,768
patients presenting with various forms of lower - limb
phlebothrombosis . -
pubmed
MATERIALS AND METHODOLOGY : We recruited 16 NOW
women with
PCOS ( NOW -
PCOS ) and 10 normally ovulating NOW
women ( control - NOW ) . -
pubmed
[ Submucosal bacterial
abscesses of the ascending colon and liver associated with portal and superior mesenteric vein
thrombosis due to
Enterococcus faecalis infection : a case report ] . -
pubmed
A 72 - year - old
woman with
diabetes mellitus was admitted with
fever and general
fatigue . -
pubmed
The
abscesses were determined to be associated with
Enterococcus faecalis infection . -
pubmed
The prospective study , not randomized and controlled , referred to the insertion of 18 implants on 9
patients with mono or bilateral
edentulism , with measurements at 1 , 3 , 6 and 12 months and an overall follow - up at 3 years , in order to evaluate the different degree of crestal
bone resorption using the submerged and transmucosal surgical technique . -
pubmed
Prevalence of
ESBL - E was 77 6 % ( 45/58 ) in
TBRI and 6 5 % ( 13/199 ) in Bj ( P & lt ; 10 - 7 ) . -
pubmed
My Approach to the use of NOACs for
stroke prevention in
patients with
atrial fibrillation . -
pubmed
METHODS : 488
participants , including 192
glaucoma , 112 age - related
macular degeneration , 91
diabetic retinopathy and 93 healthy
volunteers , completed the Assessment of Disability Related to Vision ( ADREV ) mobility course . -
pubmed
Case presentation - A five - year survival of the
patient with
glioblastoma brain tumor . -
pubmed
This paper presents an atypical case of a
patient with
brain tumor of the
glioblastoma multiforme (
GBM ) type who achieved a 5 - year survival . -
pubmed
METHODS : Prospectively collected data of
patients with true aneurysmal degeneration of the inflow artery after
fistula creation ( excluding
pseudoaneuryms , anastomotic or infected
aneurysms , or surgical complications ) , surgically repaired between January 2010 and February 2014 ( cohort study ) have been included . -
pubmed
RESULTS : 12
patients ( 75 %
men , median age 63 years ) were treated for
aneurysmal degeneration of the axillary ( 1 ) , brachial ( 6 ) , or radial ( 5 ) artery . -
pubmed
Most
patients were symptomatic (
pain [ 6 ] , distal embolization [ 1 ] ) . -
pubmed
Patients had previous
lesions that were Breast Imaging Reporting and Data System 4 and 5 based on mammography and/or ultrasonographic imaging . -
pubmed
This prospective comparative case series included sixty eyes of 42
patients undergoing
cataract surgery . -
pubmed
In the present study ,
tebuconazole and
myclobutanil enantiomers were isolated and used to evaluate the occurrence of enantioselectivity in their
acute toxicity to three non - target organisms (
Scenedesmus obliquus ,
Daphnia magna , and
Danio rerio ) . -
pubmed
Sealing a ruptured non - culprit
coronary plaque in a
patient with acute
myocardial infarction with bioresorbable vascular scaffolds . -
pubmed
A 49 - year - old
man was admitted to the emergency department suffering from a large
anterior myocardial infarction that was treated by rescue PCI . -
pubmed
METHODS AND RESULTS : Eighty
patients with
PAF were randomized in a 1:1 ratio to undergo either fluoroscopically guided pulmonary vein isolation ( PVI ) ( X+ ) or PVI without fluoroscopy ( X- ) . -
pubmed
Acute effects of Finnish sauna and cold - water immersion on haemodynamic variables and autonomic nervous system activity in
patients with
heart failure . -
pubmed
BACKGROUND : The haemodynamic response to Finnish sauna and subsequent cold - water immersion in
heart failure patients is unknown . -
pubmed
RESULTS : Cardiac output and heart rate significantly increased in all groups after sauna and cold - water immersion ( p & lt ; 0.05 ) , except for
coronary artery disease patients after sauna exposure . -
pubmed
No change in the low / high frequency ratio was found in chronic
heart failure patients . -
pubmed
In
coronary artery disease patients and controls a prolonged increase in low frequency / high frequency ratio was observed after the first sauna exposure . -
pubmed
CONCLUSIONS : Acute exposure to Finnish sauna and cold - water immersion causes haemodynamic alterations in chronic
heart failure patients similarly to control subjects and in particular did not provoke an excessive increase in adrenergic activity or complex
arrhythmias . -
pubmed
Hormone replacement therapy and the risk of
subarachnoid hemorrhage in postmenopausal
women . -
pubmed
The goal of this study was to determine the effect of HRT on occurrence of
SAH in a large prospective cohort of postmenopausal
women . -
pubmed
An MFC inoculated with
strain HJ and operated in open circuit produced 47 % and 57 % of the maximal power produced from MFCs inoculated with the known electrogen
Geobacter daltonii and the magnetotactic bacterium
Desulfamplus magnetomortis , respectively . -
pubmed
Intracranial capillary hemangioma in an elderly
patient . -
pubmed
We report an extremely rare case of rapidly rising
intracranial capillary hemangioma in an elderly
woman . -
pubmed
CASE DESCRIPTION : The 82 - year - old
woman presented with
vomiting ,
reduced level of consciousness , and worsening mental state . -
pubmed
CONCLUSION : This is the first description of rapid growth of an
intracranial capillary hemangioma in an elderly
woman . -
pubmed
All
Salmonella strains were tested for their susceptibility to the antibiotics using disk diffusion method and screened for the presence of virulence genes and class I integrons using PCR . -
pubmed
METHODS : This retrospective study involved 27
patients who presented with
periocular mass ( final diagnosis of
lipogranuloma ) and had history of facial autologous fat injection . -
pubmed
Fifty - seven
dogs with
sinonasal tumors met inclusion criteria . -
pubmed
The median overall survival times in
dogs with
tumor type of
CA ,
SA , and
OSA were 10.4 , 10.7 , and 3.1 months , respectively . -
pubmed
Dogs with the
tumor type of
OSA had shorter overall survival time than that in
dogs with
tumor type of
CA and
SA . -
pubmed
The prevalence of
heart failure (
HF ) is still increasing worldwide , with enormous
human , social , and economic costs , in spite of huge efforts in understanding pathogenetic mechanisms and in developing effective therapies that have transformed this
syndrome into a
chronic disease . -
pubmed
METHODS : The clinical data of 78
patients diagnosed with
CSP from January 2010 to December 2013 were reviewed . -
pubmed
Patients with excessive
vaginal hemorrhage underwent either emergency UAE treatment or laparotomy . -
pubmed
Diagnoses were established in 22 of 32
patients : 16
connective tissue diseases (
CTDs ) , mainly
Sjogren syndrome (
SS , 5/16 ) ,
rheumatoid arthritis (
RA , 4/16 ) , and
systemic lupus erythematosus (
SLE , 3/16 ) , and 6
nonautoimmune conditions . -
pubmed
MATERIAL AND METHODS : Data were collected for 519 eligible
gynecological cancer survivors , treated with pelvic radiotherapy , with a median follow - up of 5.8 years , using a study - specific questionnaire and medical records . -
pubmed
In phase 2 , which focuses on return to activity , the
patient continues the stretches and runs to the point of feeling iliotibial band tightness , but not
pain . -
pubmed
However ,
steroid - insensitive
patients with eosinophil - enriched
inflammation have also been described . -
pubmed
The mechanisms that underpin
infection - induced , severe
steroid - insensitive
asthma can be elucidated by using
mouse models of disease . -
pubmed
OBJECTIVE : We sought to develop representative
mouse models of severe ,
steroid - insensitive
asthma and to use them to identify pathogenic mechanisms and investigate new treatment approaches . -
pubmed
METHODS : Novel
mouse models of Chlamydia ,
Haemophilus influenzae ,
influenza , and
respiratory syncytial virus respiratory tract infections and ovalbumin - induced , severe ,
steroid - insensitive
allergic airway disease (
SSIAAD ) in BALB / c
mice were developed and interrogated . -
pubmed
Teamwork enables high level of early mobilization in
critically ill patients . -
pubmed
Reported reasons for not mobilizing patients , thereby excluding or delaying such intervention , are diverse and comprise safety considerations for high - risk
critically ill patients with multiple organ support systems . -
pubmed
This study sought to demonstrate that early mobilization performed within the first 24 h of ICU admission proves to be feasible and well tolerated in the vast majority of
critically ill patients . -
pubmed
We will highlight the diagnostic uses of
HSCA in
children , as well as pitfalls encountered . -
pubmed
Patients with non - cancerous
chronic pain completed questionnaires , and investigators also completed questionnaires . -
pubmed
CONCLUSIONS : The long - term administration of
fentanyl matrix in
patients with non - cancerous
pain can reduce the intensity of
pain and significantly improves activities of daily living and physical and mental capabilities . -
pubmed
Calcium - independent disruption of microtubule dynamics by nanosecond pulsed electric fields in
U87 human glioblastoma cells . -
pubmed
Seizure - associated central
apnea in a
rat model : Evidence for resetting the respiratory rhythm and activation of the diving reflex . -
pubmed
Respiratory derangements , including irregular , tachypnic breathing and central or obstructive
apnea can be consequences of
seizure activity in
epilepsy patients and animal models . -
pubmed
We sought to characterize
seizure - associated central
apneic episodes as an indicator of
seizure impact on the respiratory rhythm in
rats anesthetized with
urethane and given parenteral
kainic acid to induce recurring
seizures . -
pubmed
One hundred ninety central
apnea episodes ( 1.04 to 36.18s , mean : 3.2 + -3.7s ) were recorded during
seizure activity from 7
rats with multiple apneic episodes . -
pubmed
Differences between the respiratory phase at the onset of
apnea and the corresponding offset phase varied widely , even within individual
animals . -
pubmed
18F - AV-1451 PET Imaging in Three
Patients with Probable
Cerebral Amyloid Angiopathy . -
pubmed
Three
patients with probable
CAA underwent 11C - Pittsburgh Compound B (
PiB ) PET or
18F - florbetaben PET to evaluate
amyloid burden , and
18F - AV-1451 PET to evaluate paired helical filament tau burden . -
pubmed
Yet ,
human studies are limited in their ability to elucidate the physiological mechanisms by which abnormal facet loading leads to
pain . -
pubmed
Culex flavivirus (
CxFV ) is an insect - specific flavivirus infecting
Culex mosquitoes , which are important vectors of
West Nile virus (
WNV ) . -
pubmed
During both years , the
CxFV infection status of mosquito pools was associated with environmental factors such as habitat type and precipitation frequency rather than
coinfection with
WNV . -
pubmed
To explore the effects of
PD pathology on brain connectivity , we characterized with an emergent computational approach the brain metabolic connectome using
[ 18F ] FDG - PET in early idiopathic
PD patients . -
pubmed
These findings expand previous imaging evidence of altered connectivity in cognitively stable
PD patients by showing pathology - based connectivity changes and disease - specific metabolic architecture reconfiguration at multiple scale levels , from the earliest
PD phases . -
pubmed
Baseline
patient and procedural characteristics and ischemic involvement of the striatocapsular and distal MCA territory [ iSCI , as opposed to non - isolated
SCI ( niSCI ) ] were analyzed using multivariate logistic regression models . -
pubmed
RESULTS :
iSCI was detected in 53
patients ( 25.7 % ) , and
niSCI was detected in 153
patients ( 74.3 % ) . -
pubmed
In successfully reperfused
patients , TICI 3 was found to be an additional factor associated with
iSCI ( aOR 5.282 , 1.759 - 15.859 ) . -
pubmed
Patients with
iSCI had higher rates of substantial neurological improvement ( 71.7 vs. 37.9 % , p & lt ; 0.001 ) and higher rates of good functional short- and mid - term outcome ( 58.3 vs. 23.7 % , p & lt ; 0.001 and 71.4 vs. 41.7 % , p & lt ; 0.001 ) . -
pubmed
However , while
iSCI patients , in general , had a more favorable outcome , considerable heterogeneity in outcome was observed . -
pubmed
The high prevalence of
iSCI in successfully reperfused
patients with good collaterals corroborates previous concepts of
iSCI pathogenesis . -
pubmed
This may have implications for
patient rehabilitation and pathophysiological analyses of
ischemic damage confined to subcortical regions of the MCA territory . -
pubmed
The complex interplay of climate change ,
human migration influences and socio - economic factors lead to changing patterns of
respiratory infections in tropical climate but also increasingly in temperate countries . -
pubmed
But , as
human migration patterns evolve , we expect to see more
TB cases in higher income as well as temperate countries , and rise in
infections like
scrub typhus from ecotourism activities . -
pubmed
Mouse Models of
Acinetobacter baumannii Infection . -
pubmed
This unit describes basic protocols for infecting
mice through intranasal and intraperitoneal routes with
Acinetobacter baumannii to induce associated
pneumonia and
sepsis , the two most common manifestations of clinical
infections with this pathogen . -
pubmed
By selecting the appropriate protocols and bacterial
strains of different virulence , these
mouse models provide an opportunity to study the
infection pathogenesis and host - immune responses , and to evaluate the efficacies of prophylactic and therapeutic anti -
A. - pubmed
Despite great progress in diagnostic and therapeutic techniques over the last few decades , the prognosis for
patients with
LSCC remains poor . -
pubmed
These findings elucidated a novel molecular mechanism for the pathogenic mechanism in
LSCC carcinogenesis and progression , and may have a potential role in the treatment of
patients with
LSCC . -
pubmed
The
cytotoxic effects of
dimethyl sulfoxide in
mouse preimplantation embryos : a mechanistic study . -
pubmed
Conclusion : These results provide a significant contribution to finding effective protective agents to combat
DMSO mediated
reproductive toxicity for application in
human embryos in the near future . -
pubmed
A retrospective review of 101
NF - PNET patients following curative resection and lymphadenectomy was conducted . -
pubmed
These results indicate that preoperative NLR & gt;= 1.80 ,
tumor size & gt;=2.5 cm and symptomatic diagnosis are independently associated with LN
metastases for
patients undergoing resection of
NF - PNETs . -
pubmed
Inhaled
nitrous oxide can reduce the
pain perception in post Caldwell - Luc operation
patients - a randomised trial . -
pubmed
MATERIAL AND METHODS : Data were collected from all
patients ( n=1103 ) with
STEMI subjected to primary PCI in Tyumen cardiology center from 2006 to 2014 . -
pubmed
CONCLUSION : Swept - source OCTA is a reproducible technique in the assessment of macular perfusion in
diabetic patients with special regards to foveal avascular zone analysis . -
pubmed
Oxygen -
glucose deprivation was used as a model of
cerebral ischemia and IPC in cultured
rodent astrocytes and neurons . -
pubmed
Levels of Soluble Endothelium Adhesion Molecules and Complications among
Sickle Cell Disease Patients in Ghana . -
pubmed
Generally ,
SCD patients with complications had relatively higher levels of the soluble proteins compared to those in the steady - state . -
pubmed
This might reflect an ongoing
endothelial dysfunction in these
patients . -
pubmed
SCD patients with
vaso - occlusive crisis presents with a more severe pathophysiology condition . -
pubmed
Corrigendum to ' Morphological Changes in Different Populations of Bladder Afferent Neurons Detected by
Herpes Simplex Virus (
HSV ) Vectors with Cell - type - specific Promoters in
Mice with
Spinal Cord Injury ' [ Neuroscience 364 ( 2017 ) 190 - 201 ] . -
pubmed
Background :
Articular cartilage diseases are considered a major health problem , and tissue engineering using
human mesenchymal stem cells ( MSCs ) have been shown as a promising solution for cartilage tissue repair . -
pubmed
Conclusion :
Hesperidin could serve as a therapeutic agent to effectively enhance chondrogenesis of
human MSCs by inhibiting
inflammation to facilitate cartilage tissue repair . -
pubmed
The gelling time of glycol chitin /
PAA is 16 minutes at 25 C and 3 minutes at 37 C , which is convenient for doctors to inject the in - situ gel formulations into the
tumor location of
patient . -
pubmed
The antitumor activity ( IC50 ) obtained by
Centarea sinaica ; 3.1 + - 6.9 microg / ml , 14.3 + - 3.1 microg / ml and 22.7 + - 4.1 microg / ml was better than activity of
vinblastine sulphate ; 5.9 + - 0.4 microg / ml , 59.7 + - 2.1 microg / ml and 30.3 + - 1.4 microg / ml against
breast carcinoma (
MCF-7 ) ,
cervical carcinoma (
Hela ) and
colorectal carcinoma (
CACO ) , respectively . -
pubmed
Plectranthus arabicus alcoholic extract showed higher antitumor activity ; 15.3 + - 5.3 microg / ml , 28.6 + - 3.6 microg / ml and 24.3 + - 4.1 microg / ml than
vinblastine ; 21.2 + - 0.9 microg / ml , 59.7 + - 2.1 microg / ml and 30.3 + - 1.4 microg / ml against
prostate carcinoma (
Pc3 ) , cervical
carcinoma (
Hela ) and
colorectal carcinoma (
CACO ) , respectively . -
pubmed
Also , the antitumor activity of
Plectranthus asirensis against
cervical carcinoma (
Hela ) ( 37.1 + - 2.6 microg / ml ) was potent than
vinblastine sulphate ( 59.7 + - 2.1 microg / ml ) . -
pubmed
A subset of
traumatic brain injury (
TBI )
patients exhibit
cognitive deficits later in life which may be due to the underlying pathology associated with
Alzheimer ' s disease (
AD ) or
chronic traumatic encephalopathy . -
pubmed
The
beta2 - microglobulin amyloidosis is a newly recognized type of
systemic amyloidosis , which occurs in
patients with
chronic renal failure undergoing long - term hemodialysis . -
pubmed
Two
patients were referred to the Oral Medicine Clinic due to the presence of multiple nodules on the tongue and
macroglossia . -
pubmed
The
patients had history of
chronic renal failure and had been dialysed for more 20 years with bio - incompatible cellulose membrane . -
pubmed
Furthermore , in
patients with
oral amyloidosis , lesions in areas of
trauma may ulcerate and cause
pain and
dysphagia becoming necessary periodic surgical removal and regular follow - up of these
patients . -
pubmed
Virulence genes and genetic diversity assessment of Shiga toxin - producing
Escherichia coli O91 strains from
cattle ,
beef and poultry products . -
pubmed
A panel of 21 virulence genetic markers associated with
human and animal
infections was evaluated and the relatedness among
strains was determined by a multiple - locus variable - number tandem repeats analysis ( MLVA ) comprising 9 VNTR loci . -
pubmed
However , this technology will certainly improve our knowledge of the causes of
human gut infections . -
pubmed
METHODS : A retrospective study was conducted on 128
patients with Adolescent
Idiopathic Scoliosis (
AIS ) , with baseline and follow - up radiograph and surface topography assessments . -
pubmed
There was effect modification by
human immunodeficiency virus ( HIV ) status , with
HIV - positive patients having an aHR of 5.33 ( 95%CI 1.76 - 16.12 ) . -
pubmed
Further investigation into the impact of
HIV on the relation of
DM to
death is necessary . -
pubmed
Wheat production is facing the stresses of different diseases including
Fusarium head blight (
FHB ) which is more and more serious recently and leading to highly concerns . -
pubmed
In this review , we summarize the current status of the research against
FHB in
wheat and discuss the issues of
FHB resistance investigation to date . -
pubmed
Moreover , hippocampus neuron apoptosis and
cognitive impairment were significantly improved with the pretreatment of
BAY 11 - 7082 in
rats subjected to CIH . -
pubmed
The study evaluated the effectiveness of ' Mass Vaccination Campaign ( MVC ) ' implemented against the contagious transboundary OIE notified Peste des petits ruminants (
PPR ) in
sheep and
goats on the lines of '
pulse polio campaign ' for
humans in Chhattisgarh state , India . -
pubmed
Effects of micronised microencapsulated
ferric pyrophosphate supplementation in
patients with advanced
cancer and
iron deficiency : a single - centre cohort pilot study . -
pubmed
BACKGROUND :
Iron deficiency is the most common
nutritional deficiency in advanced
cancer patients and causes
anaemia . -
pubmed
The aim of this study was to evaluate the efficacy of an oral administration of 30 mg of MMFP associated with 80 mg of
ascorbic acid in advanced
cancer patients with
hyposideraemia . -
pubmed
MATERIALS AND METHODS : This was an observational prospective cohort study ( 10 months ) conducted on 42 adult
patients with advanced
cancer and serum
iron levels lower than 60 mug / dL. -
pubmed
DISCUSSION : The supplementation of 30 mg / d of MMFP in combination with 80 mg / d of
ascorbic acid in advanced
cancer patients with
hyposideraemia led to a significant increase in
sideraemia and
ferritinaemia . -
pubmed
The observations on
HPV - related
OPSCC and its prognostic implications have coincided with increasing utilization of transoral surgical approaches to
oropharyngeal tumors , such as transoral laser microsurgery ( TLM ) and transoral robotic surgery ( TORS ) . -
pubmed
These approaches were once thought to only be applicable to
patients with
low T - stage OPSCC tumors ; however , they are being increasingly utilized in locally advanced
OPSCC cases as several studies have shown that both of these transoral approaches are oncologically sound alternatives to concurrent chemoradiation therapy ( CCRT ) , which was previously the standard - of - choice treatment in
patients with locally advanced disease . -
pubmed
METHODS : CONVERT randomized
patients with limited - stage
SCLC to twice - daily ( 45 Gy in 30 fractions ) or once - daily ( 66 Gy in 33 fractions ) chemoradiotherapy . -
pubmed
Apart from a higher incidence of late
esophagitis in
patients staged with conventional imaging ( for grade & gt;=1 , 19 % versus 11 % ; [ p = 0.012 ] ) , the incidence of acute and late radiotherapy - related
toxicities was not different between the two groups . -
pubmed
We investigated the impact of pre - hydration on
tumour cisplatin concentrations in
mice , and on treatment outcomes in a clinical cohort study . -
pubmed
MATERIALS AND METHODS : Four groups of 20
mice received either no pre - hydration prior to full - dose ( 6 mg / kg ) or half - dose
cisplatin , overnight
dehydration prior to full - dose
cisplatin (
dehydration ) , or
NaCl intraperitoneally prior to full - dose
cisplatin ( pre - hydration ) . -
pubmed
In
patients , a retrospective study compared 2 historical
NSCLC cohorts which received CCRT with daily
cisplatin , with and without standard pre - hydration . -
pubmed
RESULTS : Pre - hydration significantly decreased
cisplatin tumour concentrations in
mice , comparable to
mice receiving half the dose . -
pubmed
CONCLUSION : Pre - hydration reduces
cisplatin tumour concentrations in
mice , but it does not compromise treatment outcomes in
NSCLC patients treated with daily
cisplatin and radiotherapy . -
pubmed
Schima superba is traditionally used in China for heat clearing , detoxification , and treatment of
furuncles . -
pubmed
BACKGROUND :
Clubroot disease caused by
Plasmodiophora brassicae ( Phytomyxea , Rhizaria ) is one of the economically most important diseases of Brassica crops . -
pubmed
Inter - arm Blood Pressure Difference is Associated with Recurrent
Stroke in Non - cardioembolic
Stroke Patients . -
pubmed
Recurrent
stroke increases mortality and aggravates the disability of
stroke patients . -
pubmed
We hypothesized that increased inter - arm
systolic blood pressure difference and inter - arm
diastolic blood pressure difference would be related to recurrent
stroke in non -
cardioembolic stroke patients . -
pubmed
A total of 1226 consecutive non - cardioembolic first - ever
ischemic stroke patients , in whom bilateral brachial blood pressures were measured by an automated ankle - brachial index measuring device , were included in our study . -
pubmed
During a median 24 months of follow - up , 105 ( 8.5 % )
patients experienced recurrent
stroke . -
pubmed
Patients who had inter - arm
systolic blood pressure difference & gt;=10 mmHg showed increased risk of recurrent
stroke ( hazard ratio:1.77 , 95 % confidence interval : 1.04 - 3.00 , p = 0.033 ) . -
pubmed
In conclusion , inter - arm blood pressure difference & gt;=10 mmHg may be associated with increased risk recurrent
stroke in non -
cardioembolic stroke patients . -
pubmed
Results : In total , 60
CRE were detected in the 704 stool samples ( 8.5 % ) , including 42
Klebsiella pneumoniae , 7
Escherichia coli , 3
Citrobacter freundii , 3
Klebsiella oxytoca , 3
Enterobacter cloacae , 1
Enterobacter aerogenes , and 1
Raoultella planticola . -
pubmed
SIGNIFICANCE :
Fusarium head blight causes widespread damage to crops , and chronic and acute toxicity to
human and livestock due to the accumulation of toxins during
infection . -
pubmed
To this end , we analyzed previously published whole - genome sequencing data for 384
tumor and progenitor tissues along with 423 publicly available
normal tissue epigenomic features and single cell RNA - seq data from
human livers to assess correlation patterns and extended this information to conduct in - silico prediction of the cell - of - origin for primary
liver cancer subtypes . -
pubmed
Defining spatial units that consider transmission heterogeneity ,
human movement and migration will help to set up achievable
malaria elimination milestones and guide the creation of efficient operational administrative control units . -
pubmed
When compared with the control group over 70 days , the
minocycline and
minocycline plus immunotherapy groups of
rabbits with
pythiosis showed significantly reduced
injuries . -
pubmed
Cochlear implantation in prelingually deaf
children with
white matter lesions . -
pubmed
METHODS : The data of forty - five
children with
WMLs who received CI from 2011 to 2014 were retrospectively reviewed . -
pubmed
CONCLUSIONS : The auditory and speech abilities of prelingually deaf
children with
WMLs and those without
WMLs can improve after CI . -
pubmed
OBJECTIVES : In Korea , there have been a few studies on
Korean FPV and
CPV-2 strains . -
pubmed
RESULTS : The parvoviruses
strains were newly classified into FPV ,
CPV 2 - I ,
CPV 2 - II , and
CPV 2 - III genotypes . -
pubmed
In the
strains isolated in this study , Gigucheon , Rara and Jun belong to the
FPV , while Rachi strain belong to
CPV 2 - III . -
pubmed
The root of
CPV - I strains were inferred to be originated from a USA
strain , while the
CPV - II and III were derived from Italy strains that originated in the USA . -
pubmed
Induction of
Posterior Vitreous Detachment in Pediatric
Patients by Radial Perifoveal Stripping . -
pubmed
CASE : A 5 year old
girl underwent 25- gauge pars plana vitrectomy for
optic pit maculopathy . -
pubmed
Tislelizumab in Chinese
patients with advanced
solid tumors : an open - label , non - comparative , phase 1/2 study . -
pubmed
METHODS : The purpose of this phase 1/2 , open - label , non - comparative study was to examine the safety , tolerability , and antitumor activity of tislelizumab in adult ( > = 18 years ) Chinese
patients with histologically or cytologically confirmed advanced
solid tumors with measurable disease . -
pubmed
Antitumor activity was observed in
patients with
multiple solid tumors . -
pubmed
OBJECTIVE : To analyse factors associated with the development of early and late
multiorgan failure (
MOF ) in
trauma patients admitted to the intensive care unit ( ICU ) . -
pubmed
We analysed the incidence , outcomes and the risk factors associated with early ( < 72 h ) or late ( beyond 72 h ) MOF in
trauma ICU
patients . -
pubmed
RESULTS : After excluding patients with incomplete data , 9598
trauma ICU
patients constituted the study population . -
pubmed
CONCLUSIONS :
Multiorgan failure was recorded in 10 % of
trauma ICU
patients , with early
MOF being the predominant form . -
pubmed
Interpreting auditory brainstem evoked responses and distortion product otoacoustic emissions in
diabetic patients with normal hearing . -
pubmed
We evaluated the auditory brainstem evoked responses ( ABRs ) and distortion product otoacoustic emission ( DPOAE ) results according to the presence of
DM in
subjects with normal hearing . -
pubmed
45 ears in
patients with
type 2 diabetes mellitus and 85 ears in non -
diabetic patients were finally enrolled in our study . -
pubmed
Diabetic subjects also showed significantly lower amplitudes at f2 frequencies of 1001 , 1200 , 1587 , 4004 , 5042 , and 6348 Hz than non - diabetic
subjects . -
pubmed
Additionally , the prevalence of a DPOAE response , defined as 3 dB above the noise floor , was significantly lower in
diabetic subjects than that in non - diabetic
subjects . -
pubmed
A 16S - rRNA phylogenetic analysis revealed that this
strain was most closely related to
Sphingomonas changbaiensis V2M44 T ,
Sphingomonas tabacisoli X1 - 8 T , and
Sphingomonas flavalba ZLT-5 T with 97.1 , 97.0 , and 95.0 % 16S - rRNA sequence similarities , respectively . -
pubmed
Patients with primarily mild
TBI ( n = 39 ) completed rsfMRI scans at the sub - acute ( ~10 days ) and long - term ( ~18 months ) phases . -
pubmed
Widespread increases in rsFC from the aMPFC and between the PCC and frontal regions were shown for younger
patients at time of
injury , but limited increases of rsFC were noted at ~18 months in older
patients . -
pubmed
CONCLUSION : Long - term increases in rsFC were found following
TBI , but age at the time of
injury was associated with distinct rsFC profiles suggesting that younger
patients show greater increases in rsFC over time . -
pubmed
METHODS : One hundred thirty - two
patients with active
RA and 72 healthy
subjects were included in this study . -
pubmed
We used the Vini in silico model of
cancer to perform this virtual drug screening , showing
HIV drugs to be the most effective . -
pubmed
It is concluded that careful metabolic control of the pregnant
diabetic patient results in a normal process of fetal pulmonary maturation without increased risk of
RDS . -
pubmed
It is concluded that
anovulation with in situ luteinization may be a rather frequent cause of
infertility in regularly cycling
women . -
pubmed
Two hundred forty - nine
patients with
squamous cell carcinoma seen and treated at Universtiy of Wisconsin Hospitals from 1960 - 1972 were analyzed as to recurrence rates , with emphasis on specific sites of
recurrence , salvage rates , and end results . -
pubmed
[ Determination of the metabolic clearance and production of
estradiol in
breast cancer patients at menopause ] . -
pubmed
Intravaginal insertion of a 10 cm2 silastic device with an 0.5 % concentration of
15 ( S )- 15 - methyl - prostaglandin F2alpha methyl ester alone successfully induced
abortion in 27 of 48
patients in the midtrimester and in an additional 11
patients with a concomitant infusion of
oxytocin . -
pubmed
In 8 of the 10
patients who failed to abort even with concomitant
oxytocin therapy ,
abortion was induced by serial intramuscular injections of
15 - ME - PCF2alpha ; the remaining 2 failures underwent surgical evacuation . -
pubmed
Vomiting and
diarrhea were the most common side effects and in general well tolerated by the
patients . -
pubmed
However , there was an adverse reaction in a single
patient who experienced almost constant
nausea ,
vomiting and
diarrhea . -
pubmed
The production of
secondary amines by the
human gut
bacteria and its possible relevance to
carcinogenesis . -
pubmed
40
PATIENTS WITH METASTATIC
NEUROBLASTOMA HAVE BEEN Treated by a sequential multichemotherapy made of
vincristine ,
adriamycin and
cyclophosphamide . -
pubmed
Nearly 2/3 of these streated
tumors are drug - responders : 15 complete apparent remissions which are lasting in 11
patients since four to eighteen months ; and 13 good partial remissions . -
pubmed
Genomic variation and segregation of
equine infectious anemia virus during
acute infection . -
pubmed
We employed polymerase chain reaction to investigate the distribution and the level of genome variability of
EIAV DNA in different tissues of a
horse infected with a highly virulent variant of the Wyoming
strain of the virus . -
pubmed
The prospect of identifying and developing new agents for treatment of
rhabdomyosarcomas is discussed in the light of current prognosis for
children with advanced stage disease . -
pubmed
The more complex system of identifying therapeutically active agents using
human tumor xenografts has demonstrated usefulness . -
pubmed
In six
patients with pediatric
malignancy and three newborns with suspected
septicemia ,
CL induced by
E. - pubmed
aeruginosa was measured after the administration of 150 mg / kg of intact preparations , and 4/6 of
malignancy showed increased CL by
E. - pubmed
Intimal proliferation in coronary arteries of normolipidaemic
pigs with a fixed
stenosis : the effects of
fish oil . -
pubmed
In order to investigate the effect of
fish oil on intimal proliferation of coronary arteries with a fixed
stenosis ,
piglets were fed a diet to which either 9 % ( w / w ) lard fat ( L , n = 8) or 4.5 % ( w / w ) lard fat and 4.5 % ( w / w ) mackerel oil ( ML , n = 8) was added for 4 months . -
pubmed
The
stenosis was applied by implanting a Teflon constrictor around the left anterior descending coronary artery ( LADCA ) after the
animals had been on their diet for two months . -
pubmed
Using a special in vitro assay , we tested whether retinal
ganglion cell axons in an adult
vertebrate , the
goldfish ( which can regenerate a retinotopic projection after optic nerve section ) , recognize position - specific differences in cell surface membranes of their target , the tectum opticum . -
pubmed
[ The use of the gene responsible for formation of
hemorrhage as a phenotypic marker in creating hybrid variations of
vaccinia virus ] . -
pubmed
No low dose threshold was observed in male
Sprague - Dawley rats at different single doses of
diethylnitrosamine (
DEN ) although a plateau was reached between 160 and 200 mg / kg
body weight . -
pubmed
Acute adrenal insufficiency in a
patient with
appendicitis during anesthesia . -
pubmed
vulnificus
wound infections and from
gastroenteritis caused by vibrios other than
V. - pubmed
Underlying
hepatic or neoplastic disease ( especially
leukemia ) apparently increases the likelihood and severity of illnesses caused by
V. - pubmed
Subchronic exposure to
styrene has been reported to produce
high - frequency hearing loss in
rats . -
pubmed
In
humans , hearing thresholds for higher frequencies ( greater than 8 kHz ) are also more vulnerable to
ototoxic drugs than those at lower frequencies . -
pubmed
Since
hearing loss at frequencies above 8 kHz does not seem to play a role in speech processing ,
hearing loss at frequencies above 8 kHz in
workers exposed to
styrene or other solvents might easily escape detection . -
pubmed
We evaluated 21
patients with
chorioamnionitis in labor at term and used 21 matched control subjects . -
pubmed
Use of
thiazides in
diabetic patients . -
pubmed
Genetic analysis of an inherited
deficiency of the third component of complement in Brittany spaniel
dogs . -
pubmed
Genetically determined
C3 deficiency in Brittany spaniel
dogs shares a number of biochemical and clinical characteristics with the
human disorder . -
pubmed
The current study used allotype analysis of
canine C3 in order to demonstrate that the gene for
C3 deficiency in these
dogs is also a null gene allelic to the structural gene for C3 . -
pubmed
In addition , preliminary pedigree analysis suggests that the gene for
canine C3 deficiency is apparently not closely linked to the major histocompatibility complex of the
dog . -
pubmed
Thus , it appears that
C3 deficiency in Brittany spaniel
dogs not only shares biochemical and clinical features with
C3 deficiency in
humans , but also shares some genetic characteristics with the
human disorder . -
pubmed
Dose mortality studies on
strain ' A '
mice exposed to 60Co gamma irradiation . -
pubmed
Hemodynamic and blood - gas effects of Innovar in
patients with acquired
heart disease . -
pubmed
Electron microscopic studies on the adrenal medulla and adrenal cortex of
hypertensive rats . -
pubmed
Spontaneously
hypertensive rats . -
pubmed
Electromyographic investigation of
human vocal cord paralysis . -
pubmed
A
strain of
Penicillium palitans , implicated in the
deaths of dairy
cows , produces an intracellular tremorgenic mycotoxin . -
pubmed
Glucose-6 - phosphate dehydrogenase deficiency protects
human fibroblasts against the
benzo ( a ) pyrene - induced in vitro transformation . -
pubmed
Isolation of
human surfactant from amniotic fluid and a pilot study of its efficacy in
respiratory distress syndrome . -
pubmed
The organization of intermediate filaments in normal
human colonic epithelium and colonic
carcinoma cells . -
pubmed
The presence of 12 viral ( herpes 1 and 2 ,
influenza A ( H1N1 ) , A ( H3N2 ) and B ,
parainfluenza 1 , 2 , 3 , adenovirus 5 ) and
inframicrobial ( Chlamydia , mycoplasma ,
Rickettsia burneti ) antigens was investigated by direct or indirect immunofluorescence ( IF ) reactions in exfoliated conjunctival cells from 110
patients with
nonbacterial keratitis and
keratoconjunctivitis . -
pubmed
Pyelon enlargement ( PPI decline ) in pathologically affected pregnant
patients differed from that in clinically intact patients in the third trimenon only in cases of acute
pyelonephritis ( 22
patients ) . -
pubmed
Strain specific transplantable
medullar carcinoma in DBA/2W
mice . -
pubmed
A
solid medullar carcinoma , which arose spontaneously in DBA/2W
mouse was passed in vivo in syngeneic and semisyngeneic recipients for ten generations without alteration of its morphology . -
pubmed
Intra - abdominal hemorrhage in
patients with
hemophilia is uncommon but represents a major cause of
death in
hemophiliacs . -
pubmed
Nineteen cases of
intracranial ependymal tumors were reviewed to examine the prognostic factors influencing survival of the
patients with this disease . -
pubmed
These were
patients presenting with asymmetrical
neurogenic atrophy involving one or more limbs who had no evidence of
pyramidal tract dysfunction after 3 or more years of symptoms . -
pubmed
METHODS : We reviewed our results in 165
patients with
intrahepatic stones treated by percutaneous trans - hepatic cholangioscopy and lithotripsy in the past 12 years . -
pubmed
CONCLUSIONS : Percutaneous trans - hepatic cholangioscopy and lithotripsy are good alternatives in treating primary
intrahepatic stones , especially for those
patients unsuitable for surgery . -
pubmed
Poor renal uptake of
Tc-99 m DMSA and
Tc-99 m MDP in a
patient with
Fanconi syndrome and near normal
glomerular filtration rate . -
pubmed
The authors present a
patient with
Fanconi syndrome who demonstrated poor renal uptake of
Tc-99 m DMSA and high urinary concentration of the tracer . -
pubmed
Biopsy samples obtained by endoscopy to diagnose
infection by
H. - pubmed
331
patients with the following endoscopic diagnosis were studied : normal appearance ( n = 55 ) ,
gastritis ( 87 ) ,
gastric ulcer ( 49 ) ,
duodenal ulcer ( 120 ) , and
duodenitis ( 20 ) . -
pubmed
Patients with
duodenal ulcer or
duodenitis had the highest
H. - pubmed
This is indicated by some these s as well as by the discovery of the contagious characteristics of
pityriasis versicolor by Carl Ferdinand Eichstedt ( 1816 - 1892 ) who found a fungus as the cause ( 1846 ) , which was named
Microsporon furfur later ( C. Robin 1853 ) . -
pubmed
The participant was a 37 - year - old healthy
woman ( mean cycle length = 26.7 days , SD + /- 1.8 ) with prospectively screened well - defined
premenstrual syndrome (
PMS ) , not on hormones or other drugs , and without a
psychiatric history . -
pubmed
PURPOSE : This trial evaluated the
toxicity and efficacy of high - dose
carboplatin ,
etoposide , and
ifosfamide followed by autologous stem - cell transplantation in
patients with refractory or relapsed
germ cell cancer . -
pubmed
PATIENTS AND METHODS : Between August 1989 and September 1992 , 74
patients with refractory or recurrent
germ - cell tumors received one cycle of escalating doses of
carboplatin ( 1,500 to 2,000 mg / m2 ) ,
etoposide ( 1,200 to 2,400 mg / m2 ) , and
ifosfamide ( 0 to 10 g / m2 ) . -
pubmed
Seventy - four
patients were assessable for
toxicity and 68 for response . -
pubmed
At this dosage , we treated 20
patients and observed World Health Organization ( WHO ) grade 3 and 4
hematotoxicity ( 100 % ) ,
nausea ( 100 % ) ,
diarrhea ( 30 % ) , and
hepatotoxicity ( 10 % ) . -
pubmed
All
patients developed
granulocytopenic fever . -
pubmed
Patients with
disease refractory to conventional - dose pretreatment had a poor prognosis , with only one of 23
patients surviving event - free at 7 months after high - dose chemotherapy ( HDT ) . -
pubmed
BACKGROUND : Contrary to expectation , most studies have demonstrated that initiation of an
angiotensin - converting enzyme ( ACE ) inhibitor in conventional doses in
patients with
heart failure reduces the diuretic efficacy of
furosemide . -
pubmed
METHODS AND RESULTS : Eight
patients with
heart failure treated with diuretics and
ACE inhibitors for at least 3 months were studied . -
pubmed
Cattle were evaluated on the number of treatment days required until the animals could be returned to the feedlot , and the
death loss of
cattle in the hospital pens . -
pubmed
Microinjections of
L - AP-3 ( 30 nmol /
rat ) induced a
hypotension similar to the one obtained with
t - ACPD at the dose of 6 nmol /
rat . -
pubmed
Patients with
malignant meningitis presenting with
neuropsychiatric manifestations . -
pubmed
Clinical suspicion of
malignant meningitis is prompted by neurologic
symptoms and signs in
patients at risk for this oncologic complication . -
pubmed
METHODS : Three
patients with
cancer with no
neurologic symptoms were examined for
malignant meningitis based on neuropsychiatric symptoms . -
pubmed
RESULTS : The clinical presentation of
malignant meningitis for three
patients was
neuropsychiatric . -
pubmed
None of the
patients had
delirium during their initial presentation . -
pubmed
CONCLUSIONS : It is important that clinicians recognize that psychiatric symptoms without
neurologic findings may indicate
malignant meningitis and that
malignant meningitis needs to be included in the differential diagnosis of
neuropsychiatric disorders in
patients with
cancer . -
pubmed
Antiatherogenic effects of adjuvant antiestrogens : a randomized trial comparing the effects of
tamoxifen and
toremifene on plasma lipid levels in postmenopausal
women with node - positive
breast cancer . -
pubmed
PATIENTS AND METHODS : Forty - nine postmenopausal
patients with node - positive
breast cancer were randomized in a trial that compared the effects of
tamoxifen and
toremifene on serum lipoproteins . -
pubmed
Eleven clones of
dengue virus 2 Mexican
strain were selected by the size of their lytic plaques . -
pubmed
Tumor - specific CTLs have been generated from peripheral blood mononuclear cells ( PBMC ) of healthy donors or
patients with
malignant tumors by in vitro stimulation with peptide epitopes derived from tumor - rejection antigens . -
pubmed
Based on these findings , clinical vaccine trials using these antigenic peptides have recently begun in
patients with
melanoma as well as other
tumors that express these antigens , and some
tumor responses have been seen in a limited number of
patients . -
pubmed
Congenital and early - onset
bilateral hearing impairment in
children : the delay in detection . -
pubmed
A retrospective review of 168 consecutive
children with congenital or early - onset
bilateral hearing impairment ( & gt ; 25 dB , 0.5 - 4 kHz , in the better hearing ear ) was conducted . -
pubmed
BACKGROUND : Several ecologic analyses have shown significant positive associations between mean indoor
radon concentrations and risk of
leukemia at all ages (
acute myeloid leukemia and
chronic lymphocytic leukemia ) and for
children ( all
leukemia ,
acute myeloid leukemia , and
acute lymphoblastic leukemia [
ALL ] ) . -
pubmed
Analysis of recovery time indexes in
5 - fluorouracil - treated
cancer patients . -
pubmed
Based on our previous experience in
doxorubicin - treated
patients , in whom we observed a significant increase of ventricular recovery time indexes , we analyzed these non- invasive parameters of myocardium electrical instability in forty - three
5 - fluorouracil - treated
patients , to test the hypothesis of a mechanoelectrical disarrangement occurring in
5 - fluorouracil (
5FU )
cardiotoxicity . -
pubmed
In two of these patients , each of whom experienced an episode of
peritonitis due to
S. - pubmed
Nucleoside -
nucleotide mixture increases bone marrow cell number and small intestinal RNA content in
protein - deficient mice after an acute
bacterial infection . -
pubmed
The aim of this study was to determine if intraperitoneal administration of a
nucleoside - nucleotide mixture would affect small intestinal morphology , bone marrow cell number , and DNA content in protein - deficient
mice subjected to acute
bacterial infection . -
pubmed
Mice were randomized into two groups and orally fed protein - free diet or
nucleotide - free 20 % casein diet for 10 d. The
mice in each group were divided into two subgroups and intraperitoneally administered 0.35 mL saline or
nucleoside - nucleotide mixture ( 17.5 mL / kg
body weight ) for 10 d. On day 10 , one subgroup from each major dietary group was either inoculated intravenously with
methicillin - resistant
Staphylococcus aureus or saline . -
pubmed
The pharmacokinetics of single 50 mg oral and intravenous doses of
milnacipran , a new non tricyclic antidepressant drug , were compared in 11
chronic liver impaired ( LI )
subjects and in 6 control
subjects . -
pubmed
As the unchanged drug is the only compound responsible for the activity of
milnacipran , no dosage adjustment is needed in
patients presenting
liver impairment . -
pubmed
The use of ICD 's for the treatment of
patients with
Arrhythmogenic Right Ventricular Dysplasia (
ARVD ) -
pubmed
Effect of adjuvant
tamoxifen therapy on thyroid function in postmenopausal
women with
breast cancer . -
pubmed
Behavioral disorders did not allowed the use of continuous positive pressure in this
patient . -
pubmed
Differences in the features of
osteochondritis dissecans (
OCD ) affecting the lateral and medial femoral condyles were investigated in 13
patients ( 14 knees ) treated from 1991 to 1994 . -
pubmed
Immunopathogenesis of
human gastrointestinal infection by
Anisakis simplex . -
pubmed
BACKGROUND :
Anisakis simplex is a parasite of fish , and in the case of
human infestation , it should be considered as a possible cause of
gastrointestinal disease , especially in countries where raw or undercooked fish is a frequent food . -
pubmed
All
patients underwent biopsy after emergency surgery caused by episodes of acute
abdominal pain . -
pubmed
OBJECTIVE : To determine the kinematics and kinetics of performing a weight - relief maneuver in
persons with
C5 and C6 quadriplegia . -
pubmed
SUBJECTS : Seven
persons with
C5 and C6 quadriplegia ( ASIA A and B ) with " flickers " ( grade 1/5 ) or less in wrist flexor and triceps brachii muscles . -
pubmed
The
patient was a 74 - year - old
woman who had undergone radical nephrectomy on the left side for
renal cell carcinoma on April 23 , 1990 , and had been observed as an outpatient . -
pubmed
Behavior of ambulatory blood pressure surrounding episodes of
headache in mildly
hypertensive patients . -
pubmed
METHODS : We evaluated 76
patients with mild
hypertension who underwent clinical evaluation , ambulatory BP monitoring , and questioning about the occurrence of
headache and its characteristics during monitoring . -
pubmed
The 24 - hour BP curves of
patients with and without
headache during monitoring were compared using analysis of variance for multiple factors and repeated measurements . -
pubmed
Hourly averages of BP surrounding the episode and 24 - hour mean BP of
patients with
headache were compared using paired sample t tests . -
pubmed
RESULTS : Twenty - five
participants ( 33 % ) experienced
headache during monitoring . -
pubmed
120
patients with different types of
diabetes mellitus were divided into groups by the presence and intensity of accompanying
alcoholic intoxication : group 1 - -no
alcohol intake ; group 2 - -rare
alcohol intake ; group 3 - -moderate
alcohol intake ; group 4 - -
alcoholic abuse . -
pubmed
Testing the ability of
children with
attention deficit hyperactivity disorder to accurately report the effects of medication on their behavior . -
pubmed
Children with
attention deficit hyperactivity disorder (
ADHD ) are often treated with central nervous system stimulants , making the evaluation of medication effects an important topic for applied behavior analysts . -
pubmed
Double - blind placebo - controlled procedures were used to examine whether 6
children with
ADHD could recognize the effects of their medication . -
pubmed
Furthermore , the DNA haplotype associated with disease is useful in excluding
individuals with phenotypically similar
retinal conditions . -
pubmed
CLINICAL RELEVANCE : The disease - associated haplotype allows for more accurate genetic counseling to be given to
individuals with a
Stargardt - like phenotype inherited in an autosomal dominant pattern . -
pubmed
OBJECTIVE : To evaluate the efficacy of intraoperative ultrasound in obtaining adequate
surgical margins in
women undergoing lumpectomy for palpable
breast cancer . -
pubmed
SUMMARY BACKGROUND DATA : Adequacy of
surgical margins is a subject of debate in the literature for
women undergoing breast - conserving therapy . -
pubmed
METHODS : Two groups of
women undergoing lumpectomy for palpable
breast cancer were studied , one group using intraoperative ultrasound ( n = 27 ) and the other without ( n = 24 ) . -
pubmed
CONCLUSIONS : The use of ultrasound - guided surgery optimizes the surgeon 's ability to obtain satisfactory margins for breast - conserving techniques in
patients with
breast cancer . -
pubmed
To examine the hypothesis that Pavlovian autoshaping provides an
animal learning model of
drug abuse , two studies evaluated the induction of
ethanol drinking by autoshaping procedures . -
pubmed
Similarly , Th1 vaccines would be useful in redirecting inappropriate antigen - specific immune responses in
patients with
autoimmune diseases and
allergies . -
pubmed
and peroral
Encephalitozoon cuniculi infections was compared in adoptive - transfer experiments using
severe combined immunodeficient mice . -
pubmed
In addition , if the
glomerular filtration rate reserve is compromised , all
patients ( including those taking short term therapy ) should be closely monitored for the early detection of
signs and symptoms of
renal failure . -
pubmed
OBJECTIVE : Radiosurgery - associated second
tumors have been reported in four isolated
patients during the past 2 years . -
pubmed
METHODS : A review of the English - language literature concerning
patients with radiosurgery - associated second
tumors was performed . -
pubmed
Of interest , three of the six
patients experienced complications of the radiosurgery treatment before developing second
tumors . -
pubmed
CONCLUSION : Although
patients will increasingly be reported with second
tumors after radiosurgery in the future , the overall incidence seems quite low and should not alter current radiosurgical practice . -
pubmed
[
Hyperostosis frontalis interna in a 30 year old
man with
hypophyseal - diencephalic dysregulation ] . -
pubmed
[ The biology of
Opisthorchis felineus and the spread of
opisthorchiasis in the Rostov District ; preliminary communication ] . -
pubmed
Acute
myocardial infarction in
man treated with
cortisone . -
pubmed
Streptococcus mutans belongs to the viridans group of oral streptococci , which is the leading cause of
endocarditis in
humans . -
pubmed
The study involved 150
children with
ALL . -
pubmed
While it has been shown that the matrix ( M ) protein of the
vesicular stomatitis virus (
VSV ) inhibits nuclear export of host cell mRNAs , the underlying mechanism has not been fully established . -
pubmed
In each of nine
rabbits idiotypic specificities present in the earliest
bleedings were completely replaced after a few months ; subsequent changes occurred much more slowly . -
pubmed
This compound was less potent than
permethrin against ectoparasiticide - susceptible larvae of the
lone star tick ,
Amblyomma americanum ( L. ) ( Acari : Ixodidae ) ; larvae of the southern
cattle tick ,
Boophilus microplus ( Canestrini ) ; and adult
stable fly ,
Stomoxys calcitrans ( L. ) ( Diptera : Muscidae ) in vitro , but it was significantly more potent than
permethrin against the Santa Luiza
strain of
B. - pubmed
Most
patients diagnosed with a
meningioma undergo surgical resection to relieve neurological symptoms . -
pubmed
Advocates of stereotactic radiotherapy have suggested this therapy in lieu of surgery particularly in poor surgical risk
patients ,
patients with
meningiomas in eloquent or surgically inaccessible locations and in
patients of advanced age . -
pubmed
Notwithstanding limited data ,
hydroxyurea has been modestly successful in
patients with recurrent
meningiomas . -
pubmed
PATIENTS AND METHODS : Two hundred and sixty - seven consecutive
patients , with newly diagnosed pure
seminoma of the testis , were treated with adjuvant RT between 1992 and 2000 . -
pubmed
After a median follow - up of 6.1 years ( range , 3.0 to 11.2 years ) , 11 out of 267 ( 4.1 % )
patients had developed lymph node
recurrence , resulting in an actuarial 5 - year
relapse - free survival of 96 % . -
pubmed
PURPOSE OF REVIEW : Three
cancers in people with
HIV denote an
AIDS diagnosis :
Kaposi ' s sarcoma , high - grade B - cell
non - Hodgkin ' s lymphoma and
invasive cervical cancer . -
pubmed
Endogenous mechanisms underlying the remodeling of neuronal circuitry after
mammalian CNS injury or disease remain primarily unknown . -
pubmed
METHODS AND RESULTS : At our center , from May 2000 to December 2003 , 165
patients ( mean age 64+/-10 , median 65 years ; 127
men , 38
women ) with symptomatic in - stent
restenosis underwent either intracoronary brachytherapy or sham procedure . -
pubmed
In 82
patients , intracoronary radiotherapy was carried out without complications , but one of the 83
patients who underwent sham procedure suffered small
myocardial infarction . -
pubmed
During follow - up , stent
thrombosis with subsequent non - Q - wave
myocardial infarction occurred in one
patient in each group ( 6 days and 8 months after the procedure , respectively ) . -
pubmed
At 6 months after the index procedure , repeat angiography was performed in 156 of the 164
patients with successful procedure ( rate 95 % ): restenosis (
stenosis & gt;50 % in diameter ) or reocclusion was observed in only 19 of 78 (= 24 % )
patients of the radiation but in 31 of 78 (= 40 % )
patients of the sham procedure group ( P=0.04 ) . -
pubmed
Event - free survival ( free of
death ,
myocardial infarction , target vessel revascularization ) at 1 year was 87 % for
patients being radiated and 74 % for
patients having undergone sham procedure ( P=0.05 ) . -
pubmed
Suppressive effect of hyaluronan on chondrocyte apoptosis in experimentally induced acute
osteoarthritis in
dogs . -
pubmed
Inflammatory
pain was induced by the peripheral injection of
formalin or carrageenan in awake
mice . -
pubmed
Eleven
patients underwent reoperation because of problems related to the auto and/or homograft , progression of
rheumatic mitral valve disease , and iatrogenic
coronary insufficiency . -
pubmed
We consider this procedure the best option for the surgical treatment of
aortic valve disease in
children and young adults . -
pubmed
Cancer stem - like cells in
human prostate carcinoma cells
DU145 : the seeds of the cell line ? -
pubmed
The analyses were based on the results of a standardized radiographic examination of 167
SGC horses with a mean age of 14 months . -
pubmed
An
ectopic ( intrapericardial ) lobe of the liver in a
cat . -
pubmed
Ligustrazine is an alkaloid isolated from the rhizome of
Chuanxiong (
Ligusticum chuanxiong Hort ) , which is known to possess antioxidant , anti - inflammatory , anti -
fibrosis and immunomodulative effects . -
pubmed
MATERIALS AND METHODS : After institutional review board approval and informed consent , 25
men and 22
women ( mean age , 65.8 years ) with colorectal
adenocarcinoma underwent 65 - second CT perfusion study . -
pubmed
This information will be useful in studies of
rice aneuploidy and cytogenetics . -
pubmed
METHODS : Location and degree of stenosis of involved arteries were examined by the digital subtraction angiography in 52
patients with
carotid TIA . -
pubmed
Severe
stenosis and occlusion occurred more frequently in
TIA patients with short duration ( less than 1 hour ) and multiple attacks ( more than twice ) . -
pubmed
CONCLUSION : Most
patients with
TIA of carotid systems have
stenosis in intracranial or extracranial arteries . -
pubmed
The role of an integrated back stability program in
patients with
chronic low back pain . -
pubmed
Patient satisfaction was assessed by questionnaire , 89 % of patients considering their level of
pain and
functional impairment acceptable following the programme . -
pubmed
A 30 - year - old
woman presented with cervical
lymphadenopathy and multiple non - tender , non - itching ,
erythematous papules over the neck , chest , and abdomen . -
pubmed
The earlier detection of erosion may facilitate the timely initiation of disease - modifying antirheumatic drug therapy , particularly in
patients with
undifferentiated synovitis . -
pubmed
METHODS :
Patients presenting with
synovitis for the first time were invited to participate . -
pubmed
Seventeen
patients ( 57 % ) had
RA , and 13 ( 43 % ) had
undifferentiated arthritis (
UA ) . -
pubmed
Ten
patients ( 33 % ) had US evidence of
synovitis associated with a positive power Doppler ( PD ) signal ( P = 0.04 ) . -
pubmed
Norfloxacin modulates the inflammatory response and directly affects neutrophils in
patients with decompensated
cirrhosis . -
pubmed
METHODS : Thirty - one
patients with
cirrhosis receiving
norfloxacin ( 400 mg / day ) were included . -
pubmed
CONCLUSIONS :
Norfloxacin but not
trimethoprim /
sulfamethoxazole modulates inflammatory response and directly affects neutrophils in
patients with
cirrhosis . -
pubmed
Transplantation of
human endothelial progenitor cells ( hEPCs ) may improve vascularization and left ventricular function after
myocardial infarction . -
pubmed
To this end ,
( 111 ) In - oxinate - labeled hEPCs were infused by a minimally invasive technique into the coronary arteries of immunosuppressed
Wistar rats under control conditions and after
ischemia / reperfusion . -
pubmed
We present the case of a 75 - year - old
woman who suddenly developed
hemiplegia ,
aphasia , and
reduced consciousness three hours after embolization of a
cerebral aneurysm . -
pubmed
Our studies confirm the previously held belief that
HIV-1 strains may harbor enhanced biological fitness upon recombination . -
pubmed
Preliminary results of
tranilast treatment for
patients with advanced castration - resistant
prostate cancer . -
pubmed
This study examined whether
tranilast has clinical benefit for
prostate cancer patients . -
pubmed
PATIENTS AND METHODS : Twenty - one Japanese
patients with advanced castration - resistant
prostate cancer (
CRPC ) were administered
tranilast orally . -
pubmed
CONCLUSION : Although this study involved only pilot data , it indicates that
tranilast may improve the prognosis of
patients with advanced
CRPC . -
pubmed
[ Climatic risk zoning for
banana and
litchi 's chilling
injury in South China ] . -
pubmed
Based on the 1951 - 2006 climatic observation data from 224 meteorological stations in South China ( Guangdong Province , Guangxi Autonomous Region , and Fujian Province ) and the historical information about the chilling
injury losses of
banana and
litchi , the accumulated harmful chilling for the processes with minimum daily temperature & lt ; or = 5.0 degrees C and more than 3 days was used to indicate the climatic risk of
chilling injury during the whole growth season , and an integrated climatic index with the background of climate change was constructed . -
pubmed
The maps of geographical distribution of climatic risk probability for each grade
chilling injury , and of integrated climatic risk zoning for
banana and
litchi 's
chilling injury were drawn , and the spatial variation of climatic risk for
banana and
litchi 's
chilling injury was commented . -
pubmed
The geographical distribution of climatic risk probability for
banana and
litchi 's
chilling injury showed a zonal pattern . -
pubmed
According to the integrated climatic risk index , the
banana and
litchi 's chilling
injury region was divided into three risk types , i.e. -
pubmed
OBJECTIVE : To assess the cost utility of
rasagiline or
entacapone as adjunctive therapies to
levodopa versus
levodopa /
carbidopa /
entacapone (
LCE ) versus standard
levodopa monotherapy in
patients with advanced
PD and motor fluctuations in the US . -
pubmed
With no additional cost over a 2 - year period ,
rasagiline+
levodopa presents a valuable alternative to
entacapone+
levodopa ,
LCE and
levodopa monotherapy in the treatment of advanced
PD patients . -
pubmed
Results from this cost - utility model and prior adjunctive clinical data provide ongoing support for the adjunctive use of
rasagiline in advanced
PD patients with motor fluctuations . -
pubmed
Patient centered outcomes in
prostate cancer treatment : predictors of satisfaction up to 2 years after open radical retropubic prostatectomy . -
pubmed
OBJECTIVE : The goal of the present study was to examine the prevalence of behavioural and emotional problems among
children with high - functioning
autism spectrum disorders (
ASD ) . -
pubmed
METHOD : Archival data from a total of 71
children ( Mage = 10.24 , SD = 2.91 ) diagnosed by their clinicians to have high - functioning
ASD were obtained . -
pubmed
We describe the range of radial shortening that occurs following a
fracture of the proximal radius , as well as the short - term outcome in these
patients . -
pubmed
PATIENTS AND METHODS : Over an 18 - month period , we prospectively assessed all
patients with a radiographically confirmed proximal radial
fracture . -
pubmed
Patients noted to have ipsilateral
wrist pain at initial presentation underwent bilateral radiography to determine whether there was disruption of the distal radio - ulnar joint suggestive of an
Essex - Lopresti lesion . -
pubmed
One
patient with a Mason type - I
fracture was lost to follow - up after initial presentation . -
pubmed
RESULTS : 60
patients had ipsilateral
wrist pain at the initial assessment of 237 proximal radial
fractures . -
pubmed
We divided the group of 540 cases with
EV into another 2 subgroups : without
variceal hemorrhage ( 375
patients ) and patients with a history of
variceal bleeding ( 165 cases ) . -
pubmed
The mean LS values in the group with a history of
variceal bleeding ( 165
patients ) was statistically significantly higher than in the group with no
bleeding history ( 375 patients ): 51.92 + - 1.56 kPa vs 35.20 + - 0.91 kPa , P & lt ; 0.0001 ) . -
pubmed
There appeared to be a substantial number of late
deaths , which may represent a combination of poor
patient selection and treatment failures . -
pubmed
Systemic therapy , with either cytotoxic chemotherapy and/or targeted therapies , has been established to provide benefit to
patients with
NSCLC in both the adjuvant and advanced disease settings . -
pubmed
To investigate quantitatively and objectively the effects of repeated muscle vibration ( rMV ) of triceps surae on the gait pattern in a 5 - year - old
patient with
Cerebral Palsy with
equinus foot deformity due to
calf spasticity . -
pubmed
The rMV technique seems to be an effective option for the gait pattern improvement in
CP , which can be used also in very young
patient . -
pubmed
HISTORY AND ADMISSION FINDINGS : In the 20 - year - old
patient increasing
arthralgia since the age of seven years had caused functional impairment . -
pubmed
Re : Low
testosterone concentrations and the symptoms of
testosterone deficiency according to the
Androgen Deficiency in Ageing
Males ( ADAM ) and Ageing
Males ' Symptoms Rating Scale ( AMS ) questionnaires . -
pubmed
Results are presented for two four - contact nerve - cuff electrodes stimulating bilateral femoral nerves of one
human subject with
spinal cord injury . -
pubmed
The aim of this case report is to point to the possibility of
CSS in
patients presenting with extensive
skin lesions masquerading as
Stevens - Johnson Syndrome /
Toxic Epidermal Necrolysis Syndrome (
SJS /
TENS ) . -
pubmed
All subjects provided
spot urine samples , and 125
smokers provided blood samples . -
pubmed
Formation of micronuclei and other
nuclear anomalies in exfoliated nasal and oral cells : results of a
human study with
workers in a power plant processing poultry litter . -
pubmed
Nuclear anomalies which reflect genotoxic and
cytotoxic effects were monitored in exfoliated buccal and nasal cells which were collected from
workers ( n = 25 ) of a power plant which processes
chicken manure and from controls ( n = 21 ) . -
pubmed
Taken together , the results show that anomalies that are due to
cytotoxicity are increased in the
workers and suggest that the exposure may lead to
inflammations in the respiratory tract . -
pubmed
Accuracy of MRI in the diagnosis of
meniscal tears in older
patients . -
pubmed
OBJECTIVE : The objective of our study was to determine the accuracy of MRI in diagnosing
meniscal tears in older
patients and the frequency with which abnormal MRI findings correlate with degeneration , fraying , and tears at arthroscopy . -
pubmed
CONCLUSION : The accuracy of MRI for diagnosing
meniscal tears in older
patients is high and similar to that in younger patients when only definitive findings are considered a tear . -
pubmed
To this aim , we have used the optically transparent
zebrafish larval brain and identified rapidly propagating
Ca2 + waves that determine the range of microglial responses to neuronal cell
death . -
pubmed
Feline immunodeficiency virus ( FIV ) infection of
cats provides a valuable model to study NK cell function in vivo . -
pubmed
Among them , compound 22 d showed antiproliferative effects toward several
human lung cancer cell lines (
A549 ,
H1299 , and
CL1 - 5 ) ; it exhibited
cytotoxicity against
human lung
CL1 - 5 cells similar to that of
SAHA yet without significant
cytotoxicity for normal
IMR-90 cells . -
pubmed
Age - related probability of contralateral processus vaginalis patency in
children with
unilateral inguinal hernia . -
pubmed
PURPOSE : Contralateral groin exploration with closure of a
patent processus vaginalis ( PPV ) in
children with a unilateral
inguinal hernia remains controversial . -
pubmed
Quality - of - life scores in
neurogenic thoracic outlet syndrome patients undergoing first rib resection and scalenectomy . -
pubmed
Anisometropia and
aniso - astigmatism were more common in 12- to 13 - year - old
children with
hyperopia & gt;=+2
DS . -
pubmed
A 13 mo old spayed female mixed - breed
dog presented in a nonambulatory state that was attributed to severe
myoclonus secondary to
distemper . -
pubmed
The authors hypothesized that mitigating the
myoclonus would help the
dog become ambulatory and expedite
convalescence . -
pubmed
Those injections reduced the
myoclonus , helping the
dog become ambulatory and attaining a comfortable , functional state . -
pubmed
We describe herein a rare case of a primary primitive
neuroectodermal tumor (
PNET ) in the mediastinum of a 75 - year - old
man . -
pubmed
RESULTS : Thirty - six
patients underwent caudate lobe resection for
cholangiocarcinoma ( 47.2 % ) , metastatic
colorectal cancer ( 36.1 % ) , hepatocellular
carcinoma ( 8.3 % ) , or benign disease ( 8.3 % ) . -
pubmed
CONCLUSIONS : With appropriate
patient selection , caudate lobe resection is an effective component of surgery for
hepatic disease . -
pubmed
Although
levothyroxine , a thyroid hormone , is the treatment of choice for
hypothyroidism , a significant number of
patients on thyroid hormone replacement therapy report not feeling well despite having thyroid function tests within the healthy range . -
pubmed
Based on our hypothesis , we started treating the
fatigue in
patients affected by
Hashimoto ' s thyroiditis and taking a thyroid hormone with
thiamine . -
pubmed
This is a report of the outcomes of three cases in which the
fatigue component reported by
patients with
Hashimoto ' s thyroiditis was treated with
thiamine . -
pubmed
DESIGN : Three
patients on thyroid hormone replacement because of
Hashimoto ' s thyroiditis were treated for the
fatigue component of the disease from May to July 2011 . -
pubmed
Carpal tunnel syndrome with
thenar atrophy : evaluation of the pinch and grip strength in
patients undergoing surgical treatment . -
pubmed
This aim of this study was to evaluate the progression of grip , tip pinch , key ( lateral ) pinch , and tripod pinch strengths in
patients suffering from
carpal tunnel syndrome with
thenar atrophy following surgery . -
pubmed
Between October 2008 and May 2010 , 46
patients ( 49 hands ) with
carpal tunnel syndrome associated with
thenar atrophy underwent surgery . -
pubmed
Protective effects of
selenium on
mercury induced
immunotoxic effects in
mice by way of concurrent drinking water exposure . -
pubmed
To explore the effects of
Se on
Hg - induced
immunotoxicity , female Balb / c
mice were exposed to
HgCl2- or
MeHgCl - contaminated drinking water ( 0.001 , 0.01 , and 0.1 mM as
Hg ) with coexisting
Na2SeO3 at different
Se /
Hg molar ratios ( 0:1 , 1/3:1 , 1:1 and 3:1 ) . -
pubmed
Shiga toxin - producing
Escherichia coli (
STEC )
strains are commonly found in
cattle gastrointestinal tracts . -
pubmed
BACKGROUND :
Lead malfunction is an important cause of morbidity and mortality in
patients with an implantable cardioverter - defibrillator ( ICD ) . -
pubmed
Previous computed tomography - based work on
humans who underwent imaging before and directly after
aortic dissection onset has shown an average 30 % increase in the ascending aortic diameter with acute dissection . -
pubmed
METHODS : From 2002 to 2013 , 495
patients presented with acute type A
aortic dissection to 1 center . -
pubmed
A 34 - year - old full - term pregnant
woman presented with abruptly aggravating
dyspnea . -
pubmed
This is the first report of a
patient with
peripartum cardiomyopathy who had a successful delivery with the support of ECMO , demonstrating that ECMO can serve as a rescue therapy , not only treating
peripartum cardiomyopathy but also permitting a safe delivery . -
pubmed
The type
strain of
M. - pubmed
Immunohistochemical and molecular study on the protective effect of
curcumin against
hepatic toxicity induced by
paracetamol in
Wistar rats . -
pubmed
Therefore , this study was conducted to examine the molecular levels of the protective effect of
curcumin on
paracetamol overdose induced
hepatic toxicity in
rats . -
pubmed
Control group , administered
corn oil ;
curcumin group , administered
curcumin ( 400 mg / kg BW daily intra - gastric ) dissolved in
corn oil ;
paracetamol group , administered
corn oil with a single dose of
paracetamol ( 500 mg / kg BW intra - gastric ) and protective group , administered
curcumin with a single dose of
paracetamol . -
pubmed
CONCLUSION : The results clarified the strong protective effect of
curcumin on
paracetamol induced
hepatic toxicity in
rats at the immunohistochemical and molecular levels . -
pubmed
Brain structure in
people at ultra - high risk of
psychosis ,
patients with first - episode
schizophrenia , and healthy controls : a VBM study . -
pubmed
We used high - resolution MRI and voxel - based morphometry ( VBM8 ) to analyze grey matter differences in 43 ultra high - risk subjects for
psychosis ( meeting ARMS criteria , identified through CAARMS interviews ) , 24 antipsychotic - naive first - episode
schizophrenia patients and 49 healthy controls ( groups matched for age and gender ) . -
pubmed
, first - episode
schizophrenia patients had reduced regional grey matter in left prefrontal , insula , right parietal and left temporal cortices , while the high - risk group showed reductions in right middle temporal and left anterior frontal cortices . -
pubmed
This
plant , whose infusions or complex mixtures of its metabolites are the basis for many formulas sold in pharmacies and by herbalists , has anti -
diabetic and slimming effects . -
pubmed
For bioactivity assay , compounds 4 - 7 showed significant
cytotoxicity toward
murine colorectal
CT26 and
human leukemia K562 cancer cell lines with IC50 values ranging from 6.7 to 15.3 microM and from 12.5 to 23.1 microM , respectively . -
pubmed
The objective of this study was to determine whether
MaR1 is effective at limiting
lung inflammation associated with acute and repetitive exposures to DE in an established
murine model of inhalant dust exposures . -
pubmed
Fighting
Cancer on All Fronts : Stereotactic Radiosurgery and the Role for Aggressive Primary Treatment in
Non - Small Cell Lung Cancer Patients with One Brain Metastasis . -
pubmed
BACKGROUND : We performed an updated meta - analysis of randomized placebo - controlled trials testing
memantine monotherapy for
patients with
Alzheimer ' s disease (
AD ) . -
pubmed
CONCLUSIONS :
Memantine monotherapy improved cognition , behavior , activities of daily living , global function , and stage of
dementia and was well - tolerated by
AD patients . -
pubmed
Partial resistance to homologous challenge
infections of the digenean
Echinostoma caproni in
ICR mice . -
pubmed
In the present paper , we analyse the effect of a primary
infection of
ICR mice with
Echinostoma caproni ( Trematoda : Echinostomatidae ) on the generation of resistance against homologous challenge
infections . -
pubmed
Here , the effect of the response generated against a
primary infection with
E. - pubmed
caproni and the results obtained showed that
primary infection induces partial resistance against subsequent homologous
infections in
ICR mice . -
pubmed
HIV - infected patients were randomized to add
maraviroc ( 41
patients ) or placebo ( 44
patients ) to their cART regimen for 48 weeks . -
pubmed
We examined relative survival , the ratio of survival in
cervical cancer patients to matched controls over time . -
pubmed
Changes in stage - specific relative survival for
patients with
cervical cancer compared to the general population matched by age , race , and calendar year were examined over time . -
pubmed
There were no statistically significant improvements in relative survival over time for
women with stage IV
tumors . -
pubmed
CONCLUSION : Relative survival has improved over time for
women with
stage I - III cervical cancer , but has changed little for those with metastatic
disease . -
pubmed
We assessed regional amyloid load using AV45 - PET , neuronal metabolism using
FDG - PET , and gray matter volume using structural MRI in 473
participants from the
Alzheimer ' s Disease Neuroimaging Initiative , including preclinical , predementia , and clinically manifest
AD stages . -
pubmed
25 wk of gestation in
human pregnancy , rescues early origins of
cardiovascular dysfunction during
hypoxic development . -
pubmed
METHODS : Between January 2009 and December 2012 , 38
patients with combined
injury of meniscus bucket handle tear underwent arthroscope surgery by the method of both side stereo suture . -
pubmed
The aim of this work was to find out if there is a statistically significant correlation between these different predictors and their correlation with the central corneal thickness for refractive non - keratoconic Egyptian
patients trying to achieve a better decision and avoiding
ectasia . -
pubmed
METHODS : This case - control study involved 142 eyes ( of 77
patients with various
refractive errors ) arriving at the refractive surgery unit in the Research Institute of Ophthalmology in Giza ( Egypt ) in 2014 - 2015 seeking excimer laser ablation . -
pubmed
METHODS : From September 1991 to December 2002 , 2150
patients with multivessel
coronary artery disease underwent isolated myocardial revascularization with BIMA grafting . -
pubmed
miR-125b expression in the sputum of 50
asthmatic children and 50 age- and sex - matched healthy controls were assessed by quantitative RT - PCR ( qRT - PCR ) . -
pubmed
Additionally , intranasal delivery of miR-125b mimic in
mice was performed to study its effects on house dust mite - induced
allergic airway inflammation mouse models . -
pubmed
We found that miR-125b expression was decreased in the sputum of the
asthmatic patients especially in
eosinophilic asthma . -
pubmed
BACKGROUND : A role of
Chlamydia trachomatis in
HPV - induced cervical
carcinogenesis has been reported for
cervical cancer but studies on
cervical adenocarcinoma are limited . -
pubmed
METHODS : A total of 1,553 cervical smears taken up to 26 years before diagnosis in a large population - based nested case - control study of cervical
adenocarcinoma (
AC , 132 cases with matched controls ) , and
adenocarcinoma in situ (
AIS , 159 cases with matched controls ) were tested for
C. - pubmed
MATERIAL AND METHODS : We collected data from 153
patients with
MS . -
pubmed
Patients filled out the Pittsburgh Sleep Quality Index ( PSQI ) , the Hospital Anxiety and
Depression Scale , and one item of the Short Form-36 regarding
pain . -
pubmed
Potential immunological markers for diagnosis of
human strongyloidiasis using heterologous antigens . -
pubmed
Strongyloides venezuelensis is a parasitic nematode of rodents that is frequently used to obtain heterologous antigens for immunological diagnosis of
human strongyloidiasis . -
pubmed
venezuelensis for immunodiagnosis of
human strongyloidiasis . -
pubmed
venezuelensis antigens for use in immunodiagnostic assays for
human strongyloidiasis . -
pubmed
Among these , two compounds 35 , and 36 showed a significant inhibition in male
Wistar rats , and identified as potential lead molecules for anti -
hyperuricemic drug development . -
pubmed
Consumers were unable to detect flavor differences in oil - soluble fortified milks , but trained panelists documented a
faint carrot flavor in oil - soluble fortified skim milks at higher
vitamin A concentrations ( 3,000 - 6,000 IU ) . -
pubmed
Therefore , the purpose of this study was to quantify balance performance in both
ankle osteoarthritis patient groups . -
pubmed
Twenty - two unilateral and twenty - one bilateral
ankle osteoarthritis patients performed three 10 - s quiet standing trials with their feet together . -
pubmed
Humanin rescues cultured
rat cortical neurons from
NMDA - induced
toxicity through the alleviation of
mitochondrial dysfunction . -
pubmed
Video - assisted thoracic surgery is associated with better short - term outcomes than open thoracotomy in adult
patients with intralobar
pulmonary sequestration . -
pubmed
OBJECTIVES : This study was aimed to investigate potential benefits of thoracoscopic surgery for intralobar
pulmonary sequestration in adult
patients in terms of short - term surgical outcomes when compared with open surgery . -
pubmed
CONCLUSIONS : Video - assisted thoracic surgery is associated with less
intraoperative bleeding and shorter postoperative hospital stay than is open thoracotomy in surgical resection of intralobar
pulmonary sequestration in adult
patients . -
pubmed
Furthermore , using a combination therapy of the chelating agent
deferoxamine (
DFX ) and
Trolox ,
liver injury and oxidative stress markers were also reduced in
iron overloaded
mice . -
pubmed
We analyzed 73
tumour samples from 21
patients and compared cellular density , cell proliferation , and the degree of vascularity . -
pubmed
PURPOSE : Evaluating the role of surgery and the extent of
tumor resection on the outcome of
patients with localized initially unresectable
neuroblastoma (
NB ) . -
pubmed
PATIENTS AND METHODS : This was a retrospective case review study including
patients with localized initially unresectable
NB . -
pubmed
RESULTS : A total of 202
patients with
NB were included . -
pubmed
Fifty - five ( 57.2 % ) were in good response after primary chemotherapy and 41
patients ( 42.7 % ) had persisting
IDRFs , nine of them had biopsy only , and a follow - up strategy was considered in the other 32
patients . -
pubmed
CONCLUSION : In
children with localized initially unresectable
NB , surgical resection was the only significant risk factor associated with better survival . -
pubmed
Skin and soft tissue infection was diagnosed in 1 of 22
patients ( 4.55 % ) . -
pubmed
Introduction : Treatment of
infection within bone is difficult , and conventional surgical treatment brings intense
pain to the
patients physically and mentally . -
pubmed
The lure of
death : suicide and
human evolution . -
pubmed
At some point in evolutionary history ,
human beings came to understand , as no non -
human animals do , that
death brings to an end a person 's bodily and mental presence in the world . -
pubmed
In almost half of the
patients ,
type I cryoglobulinemia is characterized by severe cutaneous involvement . -
pubmed
PATIENT CONCERNS : A 71 - year - old
man comes to our observation because of the onset of persistence of
paresthesia and painful
acrocyanosis in the fingers and toes . -
pubmed
Impact of induction regimen and allogeneic hematopoietic cell transplantation on outcome in younger
adults with
acute myeloid leukemia with a monosomal karyotype . -
pubmed
Monosomal karyotype confers a poor prognosis in
patients with
acute myeloid leukemia . -
pubmed
Here , we determined the impact of the type of remission - induction chemotherapy and the impact of having a donor in younger
acute myeloid leukemia patients with a monosomal karyotype included in two phase III trials . -
pubmed
monnieri extracts were investigated in
Vibrio harveyi mutagenicity assays . -
pubmed
METHODS : We performed electroanatomic mapping and RFCA in the left ventricles of 8
swine with
myocardial infarction . -
pubmed
Currently , imported and exported
tomato fruit are not monitored for
TYLCV infection because they are not considered to represent a potential risk as a virus source for whiteflies . -
pubmed
We present the clinical and radiological findings of two 5 - year - old
children with
pseudomalignant MO due to prolonged immobilization . -
pubmed
Vaccines for
Pseudomonas aeruginosa have been of longstanding interest to immunologists , bacteriologists , and clinicians , due to the widespread prevalence of
hospital - acquired infection . -
pubmed
Comparative proteomic analysis of saliva from
dogs with and without
obesity - related
metabolic dysfuntion . -
pubmed
Dogs develop only some of the components of the
human metabolic syndrome (
MetS ) . -
pubmed
Thus , in order to study possible
MetS - related alterations in
dogs ,
human MetS criteria were adapted to define
canine MetS or so - called
obesity - related
metabolic dysfunction (
ORMD ) . -
pubmed
The main objective of this study was to identify changes in the salivary proteome of
obese dogs with
ORMD in comparison with
obese dogs without
ORMD which may constitute potential salivary biomarkers for assessing
ORMD . -
pubmed
In a first phase , 12 adult
obese dogs with
ORMD ( N = 6 ) and without
ORMD ( N = 6 ) were included in the study . -
pubmed
Subsequently , and with the aim of validating and strengthening the results , additional 12
obese dogs ( 6 with and 6 without
ORMD ) were tested in an independent experiment following the same protocol . -
pubmed
SIGNIFICANCE : This is the first study evaluating proteomes of saliva in
dogs , as a non invasive sample , in order to increase knowledge about the metabolic / physiopathological changes related to
obesity - related
metabolic dysfunction (
ORMD ) together with the identification of potential biomarkers for its diagnosis . -
pubmed
As approximately 20 % of
dogs with naturally occurring
obesity were described to suffer
ORMD associated with
insulin resistance and
hypoadiponectinemia , the fact that indicate possible links between
ORMD and associated diseases . -
pubmed
METHODS : Retrospective chart review of
veterans with
chronic hepatitis C infection who received more than 1 week and up to 6 weeks ( 8 - 42 days ) of
DAA therapy with the initiation day between January 1 , 2015 , and October 15 , 2018 , at Bay Pines Veterans Affairs Healthcare System . -
pubmed
Clinical case : 25 - year - old
woman who presented
oligomenorrhea , increased weight ,
decreased visual acuity and
chronic headache . -
pubmed
Transsphenoidal surgery was performed with complete resection of lesion , and during short - term follow - up it was observed
recurrence , which is why the
patient needed two more interventions . -
pubmed
Future evaluation of the vagus nerve and brain of
animals with
colitis will be key to assess the contribution of
colitis - induced ENS alpha - syn pathology to
PD - like pathology in the brain . -
pubmed
Four primiparous and 16 multiparous mid - lactating dairy
cows were assigned according to milk yield ,
body weight ( BW ) , days in milk , and parity into 2 groups and fed 1 of the 2 diets for 34 d. The first 13 d were used for diet adaption , followed by data collection of nutrient intake , chewing activity , sorting behavior , milk production , and nutrient digestibility for the last 21 d of the experiment . -
pubmed
Beneficial effects of
dapsone on
ischemia /
reperfusion injury following torsion / detorsion in ipsilateral and contralateral testes in
rat . -
pubmed
Therefore , the aim of this study was to investigate the influence of
dapsone on
ischemia / reperfusion ( I / R ) injury in bilateral testes after unilateral
testicular torsion / detorsion ( T / D ) in
rats . -
pubmed
It was concluded that
dapsone had a protective impact on I / R
injury in the
rat model of testicular T / D , and this effect was most likely induced by anti - inflammatory and anti - oxidative properties of
dapsone . -
pubmed
Here we report 2 unusual cases involving very young
children with
pneumorrhachis secondary to
pneumomediastinum and present a review of the relevant literature . -
pubmed
Case 1 involved a 4 - year - old
girl who presented with
wheezing , violent
coughing , and
dyspnea associated with
bronchiolitis . -
pubmed
Case 2 involved a 3 - year - old
boy who presented with
wheezing , violent
coughing , and
dyspnea associated with
interstitial pneumonia possibly caused by
graft - versus - host disease with
human herpesvirus 6 infection after allogeneic hematopoietic stem cell transplantation . -
pubmed
Because
pneumorrhachis is rare in
children and neurological sequelae may be difficult to identify , close clinical , and radiographic observations are necessary . -
pubmed
Identification and complete - genome phylogenetic analysis of an
epizootic hemorrhagic disease virus serotype 7
strain isolated in China . -
pubmed
An
epizootic hemorrhagic disease virus (
EHDV )
strain designated
YN09 - 04 was isolated from sentinel
cattle in China . -
pubmed
These results suggest that the genome of YN09 - 04 likely originated from a reassortment event between
EHDV strains that were similar to the current Japanese and Australian
strains and that
YN09 - 04 and some EHDVs from Japan and Australia share the same ancestors . -
pubmed
MATERIALS AND METHODS : We enrolled asymptomatic
diabetic patients as well as prediabetic and normoglycemic
subjects to test sensory nerve excitability , and we analyzed those findings and their correlation with clinical profiles . -
pubmed
METHODS : A multi - institution , prospective pilot study of
patients with first presentation for
PSP at 9
children 's hospitals was performed . -
pubmed
JA - Ile - macrolactone 5b - treated
tea plants significantly inhibited the larvae
weight gain of
Ectropis obliqua larvae and the lesions caused by
Colletotrichum camelliae . -
pubmed
obliqua , but it did not directly influence the
infection of
C. - pubmed
Tuberculosis is a very serious
respiratory infectious disease , caused by the bacillus
Mycobacterium tuberculosis , which generates a relevant societal and clinical burden . -
pubmed
Firstly , the
TCA cycle was rewired for
alpha - KG production starting from
pyruvate , and the engineered
strain E. - pubmed
A 24 - year - old
woman presented with
subdural hemorrhage , and subsequent radiology depicted an osteolytic mass - like lesion in the sphenoid bone . -
pubmed
DESIGN , SETTING , AND PARTICIPANTS : Costs for surgical care for consecutive
patients with localized
prostate cancer treated from November 2018 to November 2019 were itemized and evaluated . -
pubmed
Texture analysis on bi - parametric MRI for evaluation of aggressiveness in
patients with
prostate cancer . -
pubmed
METHODS : A total of 116
patients who had been confirmed as
prostate adenocarcinoma by radical prostatectomy or biopsy were divided into a training ( n = 65 ) and a validation dataset ( n = 51 ) . -
pubmed
Dynamic organ preservation techniques , modulation of
ischemia - reperfusion and preservation
injury , and allograft therapies are in the spotlight of scientific interest in an effort to improve allograft utilization and
patient outcomes in
KT . -
pubmed
Androgens by immunoassay and mass spectrometry in
children with
46,XY disorder of sex development . -
pubmed
METHODS : Nineteen
patients with 46,XY
DSD were evaluated ; all of them were prepubertal and non gonadectomized . -
pubmed
PARTICIPANTS : Ten lean and
obese healthy
men . -
pubmed
INTRODUCTION : Weekly
iron - folic acid (
IFA ) supplements are recommended for all menstruating
women in countries where
anaemia prevalence is > 20 % . -
pubmed
Including
folic acid might reduce the risk of a
neural tube defect (
NTD ) should a
woman become pregnant . -
pubmed
Moreover ,
women in the 2.8 mg group were seven times ( RR 7.3 , 95 % CI 3.9 to 13.7 ; p<0.0001 ) more likely to achieve an RBC
folate > 748 nmol / L , a concentration associated with a low risk of
NTD , compared with the 0.4 mg group . -
pubmed
RETRACTION NOTICE : Exosomes promote restoration after an experimental
animal model of
intracerebral haemorrhage . -
pubmed
For instance , folding - deficient variants of the
human transporters for
dopamine or
GABA lead to
infantile parkinsonism /
dystonia and
epilepsy , respectively . -
pubmed
Candida parapsilosis complex infection in a
cutaneous lesion from a
dog : Spotlight on an opportunistic pathogen of potential increasing importance . -
pubmed
Marked
pyogranulomatous inflammation and fungal organisms were present , identified as
Candida parapsilosis complex by MALDI - ToF following fungal culture . -
pubmed
BACKGROUND :
Regorafenib has been approved among the treatment options for
patients with advanced stage
colorectal cancer (
CRC ) ,
hepatocellular carcinoma (
HCC ) , and
gastrointestinal stromal tumors (
GIST ) . -
pubmed
Toxicity and intolerability of
regorafenib lead to treatment discontinuation in nearly a quarter of
patients . -
pubmed
PURPOSE : The purpose of this study was to evaluate etiologies , management , and outcomes of
patients with giant
retinal tears ( GRTs ) undergoing primary surgery at a tertiary referral center . -
pubmed
[
Skin diseases in
workers coming in contact with inhibitors of the atmospheric corrosion of metals ] . -
pubmed
A statistically significant prolongation of latency of the main deflections ( N1 , P max and N2 ) was observed in the group of 14
patients with
optic nerve damage , while in 10
patients with lesions above the chiasma different , often normal responses were obtained . -
pubmed
The author reviewed electrocardiographic records of 150
patients with
acute stroke and 150 age- and sex - matched controls , to assess the relative frequencies of ECG abnormalities among the pathophysiologic categories of
stroke , and to distinguish new abnormalities at the time of the
stroke from those noted on prior tracings . -
pubmed
Of the 150
patients with
stroke , 138 ( 92 % ) showed ECG abnormalities . -
pubmed
Patients with
cerebral embolus had a significantly increased frequency of
atrial fibrillation ( 9
patients , 47 % ) ; and with
subarachnoid hemorrhage an increased frequency of
QT prolongation ( 20 , 71 % ) and
sinus arrhythmia ( 5 , 18 % ) . -
pubmed
Stroke patients had an increased frequency of pathologic Q waves ( 30 patients , 20 % ) and
left ventricular hypertrophy ( 39 , 26 % ) , but these were not new findings at the time of the
stroke . -
pubmed
Tympanic membrane perforations in
cats : configurations of losses with and without ear canal extensions . -
pubmed
Among 140
patients with
hydatid echinococcosis of the liver complications were noted in 58 cases :
suppuration of the
cyst - in 38 ( 27.1 % ) ,
cyst rupture in the anterior abdominal wall and abdominal cavity - in 4 ( 2.8 % ) , in bile ducts - in 10 ( 7.1 % ) , its
rupture into the right lung lower lobe ,
calcification of the cyst was noted in 4
patients ( 2.8 % ) . -
pubmed
Urodynamic investigations were performed in 9
males , suffering from
dysfunction of the bladder neck (
detrusor bladder neck dyssynergia ) . -
pubmed
The parameters of micturition were compared with the values in normal males and in
patients with
prostatic obstruction . -
pubmed
Vascular proliferation and mononuclear cell infiltration are prominent changes observed in synovium from actively inflamed joints of
patients with
rheumatoid arthritis . -
pubmed
Eight ( 6.6 % )
patients had postoperative
hematomas larger than 4 cm in diameter , which delayed the start of RT by 2 to 3 weeks . -
pubmed
Eighty - two
patients were studied ; 40 were normotensive and 42 had
hypertension currently controlled by pharmacological therapy . -
pubmed
In antiinflammatory action , its half effective dose ( ED50 ) was 0.12 mg / kg with the model of croton oil induced
ear swelling of
mice . -
pubmed
In this study , eighty limbs ( 71
patients ) with clinically suspected
deep venous thrombosis (
DVT ) were investigated by both venography and Doppler ultrasonography . -
pubmed
A sample of 700 female
epileptic outpatients was examined between 1985 and 1987 . -
pubmed
A 37 - year - old
man presented to the emergency department after an attempt to self - treat his
priapism with saltpeter
( K+NO3 ) . -
pubmed
[ Recurrent
ventricular fibrillation in a
patient with angiographically normal coronary arteries and intermittent ST segment elevation ] . -
pubmed
We report on a
patient who was admitted to the hospital because of severe
angina pectoris . -
pubmed
Amiprilose hydrochloride , a
3 - substituted glucose derivative , was found to inhibit the proliferation of
human fibroblasts and keratinocytes originating from
psoriatic lesions . -
pubmed
Noradrenergic involvement in pinealectomy induced
convulsions in
gerbils . -
pubmed
Gerbils treated with various noradrenergic compounds were pinealectomized (
PINX ) or sham - operated ( SHAM ) and observed for
convulsive activity . -
pubmed
Although declines in cortical and hypothalamic
norepinephrine content were found after
alpha - methylparatyrosine (
alpha MPT ) or
PINX , treatment with
alpha MPT did not produce
convulsions in SHAM
gerbils or in
gerbils which were
PINX one week earlier . -
pubmed
Likewise ,
alpha MPT did not increase the number or severity of
convulsions observed in acutely PINX
gerbils . -
pubmed
Treatment with
propranolol or
isoproterenol did not have any effect on
convulsive activity of PINX
gerbils , except that
isoproterenol increased the excitability of all the
gerbils . -
pubmed
Avoiding splenectomy in the treatment of
children with
splenic injury . -
pubmed
Ninety - two consecutive
patients with
traumatic rupture of the spleen were studied . -
pubmed
A third of the
patients in each group had associated
injuries ,
renal injury being the most common
intraabdominal lesion . -
pubmed
Among the 40
patients who were treated conservatively , a biphasic course was seen in 23 : one or two days after the accident a period of increased
pulse rate ,
fever and increased
abdominal tenderness and
pain followed , but no evidence for a delayed
rupture was found . -
pubmed
In the 19
patients evaluated , no
thromboses were detected nor any narrowing greater than 10 % of proximal diameter as seen by angiography . -
pubmed
Effects of antidepressants on
alcohol - induced
gastric mucosal injury in
rats . -
pubmed
Results showed marked
glucose intolerance with peak value 60 min after
glucose load in cirrhotic
patients with normal fasting blood
glucose . -
pubmed
These concentrations were compared with the levels obtained by infusion to the
dog , which cause serious
cardiac disorders with 6,000 to 8,000 ng.ml-1 levels , and elicit
ventricular fibrillation with 8,000 to 10,000 ng.ml-1 . -
pubmed
[ Treatment of
acute myeloblastic leukemia in elderly
patients with low - dose
cytosine arabinoside ] . -
pubmed
Forty - eight
patients , aged from 65 to 88 years , presenting with de novo
acute myelogenous leukemia were treated with a low - dose
cytarabine regimen ( 10 mg / sq.m subcutaneously 12 - hourly for 15 to 28 days ) . -
pubmed
Bleeding occurred in 28
patients and
fever was noted , also in 28
patients . -
pubmed
Four
patients died of
infection during induction treatment . -
pubmed
It is concluded that low - dose
cytarabine is an alternative to intensive chemotherapy in elderly
patients with
acute myelogenous leukemia . -
pubmed
Abomasal
fistulas in dairy
cows . -
pubmed
Abomasal
fistulas were corrected surgically in 9 adult Holstein
cows . -
pubmed
All
fistulas were in the right paramedian area and were draining blood and/or ingesta from
necrotic abomasal tissue ( 8
cows ) or ruminal tissue ( 1
cow ) . -
pubmed
Surgery was performed immediately in
cows with consistent
hemorrhage from the fistulated tissue ( 4
cows ) . -
pubmed
Surgery was delayed to reduce rumen contents if
bleeding was absent or considered negligible ( 4
cows ) or to stabilize the patient ( 1
cow ) . -
pubmed
Outcome following the
fistula resection was successful in the 7
cows discharged from the clinic . -
pubmed
Invasion of erythrocytes by
Plasmodium falciparum malaria parasites : evidence for receptor heterogeneity and two receptors . -
pubmed
Plasmodium falciparum malaria parasites with different capabilities of invading
sialic acid - deficient erythrocytes were identified . -
pubmed
P falciparum malaria parasites probably possess two receptors : one that binds to a
sialic acid - dependent ligand and another that binds to a
sialic acid - independent ligand . -
pubmed
Out of a series of 900 biopsy - proven cases of skeletal "
fibroxanthoma " (
nonossifying fibroma ,
fibrous cortical defect ) , we studied 72
patients with more than one lesion . -
pubmed
[ Nonsurgical treatment of
pulmonary valve stenosis using balloon valvuloplasty in
children ] . -
pubmed
We reviewed the manner of presentation and
tumor stage in 56 consecutive
patients with
renal cell carcinoma treated surgically between 1961 and 1973 ( group 1 ) and compared them to 46
patients treated similarly between 1980 and 1984 ( group 2 ) . -
pubmed
[ Cardiac output and total peripheral resistance in experimental
arterial hypertension in
dog ] . -
pubmed
Antitumor activity of
vinzolidine in the
human tumor clonogenic assay and comparison with
vinblastine . -
pubmed
Vinzolidine (
VZL ) , a semisynthetic
vinblastine (
VLB ) derivative , was tested against a variety of
solid tumors in the
human tumor clonogenic assay ( HTCA ) . -
pubmed
The
genotoxicity of
4,4 '- methylenebis-2 - chloroaniline in
rat ,
mouse , and
hamster hepatocytes . -
pubmed
The case of
prostatic adenocarcinoma described has only been reported in one other nonhuman
primate . -
pubmed
In the
mouse repeated high doses ( 480 mg / kg / day ) cause
paralysis of the hind limbs but there is no effect on fertility . -
pubmed
A case report is presented in which a
patient with well - documented
pigmented villonodular synovitis sustained a disruption of the popliteal artery without evidence of penetration of the posterior capsule . -
pubmed
The article discusses the results of endoscopic examination of 44
children with
extrahepatic portal hypertension before and after various types of portocaval shunting . -
pubmed
Effect of
Septilin , an ayurvedic formulation proven to be effective in the therapy of
chronic infections , was investigated on the phagocytic system and humoral response in
rats and
mice . -
pubmed
coli - induced
abdominal sepsis in normal
mice and in
Staphylococcus aureus - induced
sepsis in
neutropenic mice . -
pubmed
Contents of trace elements in the hair of
aplastic anemia patients and their treatment based on an overall analysis of
symptoms and signs . -
pubmed
The content of 12 trace elements in the hair of 20
aplastic anemia patients was determined and compared with that of normal subjects as control . -
pubmed
In summary , the mechanism of
sudden death in this
patient was revealed by ambulatory ECG monitoring , and the involvement of neural and myocardial factors are proposed . -
pubmed
Growth of
human myeloid leukemias in the
human marrow environment of SCID - hu
mice . -
pubmed
We describe here an application of this
animal model , the SCID - hu
mouse , to the study of
human myeloid leukemias . -
pubmed
BM cells from 8
patients with various types of
myeloid leukemias were injected directly into
human bone grafts in the
SCID - hu mouse . -
pubmed
Thus ,
human myeloid leukemia cells could be reproducibly propagated in the
human marrow environment in
SCID - hu mice . -
pubmed
The differentiation of
promyelocytic leukemia cells in the
SCID - hu mice was induced by
all - trans retinoic acid , suggesting that the biologic features of the
leukemia cells were maintained as well . -
pubmed
This model may provide a useful tool for studying the biology of
human myeloid leukemia as well as for evaluating new therapeutic modalities for
myeloid leukemias . -
pubmed
The
thrombi formed by batroxobin were rapidly lysed in control
animals , while the rate of lysis was markedly attenuated in
rats given endotoxin . -
pubmed
SUBJECTS : 66
overweight men ( mean age 43.4 + /- 5.7 y ,
BMI 29.0 + /- 2.6 kg / m2 ) . -
pubmed
Intravenous infusion of
diltiazem causes
uricosuria with concomitant
hypouricemia in
rats . -
pubmed
Immunophenotyping of
human HT29 colon cancer cell primary
tumours and their
metastases in
severe combined immunodeficient mice . -
pubmed
The immunophenotype of
HT29 human
colon cancer cells implanted into
severe combined immunodeficient mice was assessed in primary
tumours and their metastases in the lungs using an indirect immunohistochemical method . -
pubmed
CLINICAL PRESENTATION : A 41 - year - old
man was admitted with a 3 - year history of
low back pain and
sciatica . -
pubmed
Therefore , we decided to operate on the
patient having made a diagnosis of
lumbar disc disease . -
pubmed
CONCLUSION : The
patient was immediately relieved of
pain and was discharged on the 7th day after the operation with normal muscle strength . -
pubmed
It seems probable that in some
patients with "
failed back syndrome , "
intraradicular or intradural disc herniation is the cause of failure . -
pubmed
All
patients had chronic
HCV infection with confirmation of
chronic hepatitis on liver biopsy . -
pubmed
Although the plasma half - lives are longer and marrow dose higher for radiolabeled huBrE-3 compared with the
murine construct , the excellent
tumor localization , good
tumor dosimetry , and low immunogenicity support the use of
90Y - huBrE-3 antibody for radioimmunotherapy of
breast cancer . -
pubmed
PURPOSE : To measure under carefully controlled conditions the effects in the
rabbit eye of commonly used therapeutic agents for
glaucoma . -
pubmed
However , rapid and high cytotoxic activities against
HCV core were not only detected after immunization with peptides containing the CTL epitope but also as a result of
infection with recombinant
vaccinia virus carrying the
HCV core gene after immunization with the Th epitope alone . -
pubmed
The risk of
duodenal ulcer is enhanced by
infection with proinflammatory
H. - pubmed
Progressive damage to the duodenum promotes gastric
metaplasia , resulting in sites for
H. - pubmed
OBJECTIVE : To determine the prognosis and distribution of
ischemic injuries caused by inappropriate bandaging of the lower limb in
dogs and
cats . -
pubmed
ANIMAL POPULATION : Eleven client - owned
animals , including 9
dogs and 2
cats with a history of
injuries consistent with incorrect application of a bandage . -
pubmed
METHODS : Medical records for
dogs and
cats referred to the Queen 's Veterinary School Hospital with
limb wounds between 1995 and 1999 were reviewed for clinical history and referring veterinary surgeons ' reports , indicating that the
injury was directly related to the application of a bandage to the limb . -
pubmed
Of the 11
animals , 5 required full - thickness skin grafts , 3 had to have digits amputated , and 2 required
limb amputations . -
pubmed
PURPOSE : To present the ophthalmic manifestations of
patients with
Gilles de la Tourette syndrome (
GTS ) . -
pubmed
METHODS : Sixteen
children ( average age 11.5 years ) , with multiple motor and
vocal tics , with a diagnosis of
GTS , were included in this study . -
pubmed
Eleven
patients ( 68 % ) had
eye tics ; nine had clonic
blepharospasm and two had
involuntary gaze deviations . -
pubmed
Four cooperative
children underwent visual field examination with Goldmann perimeter , no
visual field defect was detected . -
pubmed
Three
patients had
strabismus ( one alternating
exotropia and two partially
accommodative esotropia ) . -
pubmed
The symptoms improved considerably in 82 % of the
patients with
eye tics on treatment with a neuroleptic (
pimozide ) . -
pubmed
Ophthalmologists should consider a diagnosis of
GTS in the absence of any organic eye pathology that may cause
blepharospasm and refer these cases to a
child psychiatrist . -
pubmed
OBJECTIVES : To investigate the clinical profiles of
subjects referred for
allergy evaluation ; to prospectively reduce the frequency of evaluation by assessing the persistence , during clinical use , of non - reactivity to contaminant / additive - free
mepivacaine ; and to determine the usefulness of a diagnostic protocol involving patch testing . -
pubmed
True
allergic reactions to contaminant / additive - free
mepivacaine were not observed in our
patient series . -
pubmed
The authors then applied these methods to
[ ( 11 ) C ] MP4A PET data in 12 healthy subjects and 26
patients with
Alzheimer disease (
AD ) using the cerebellum as the reference region . -
pubmed
An out - patient second - line chemotherapy with
gemcitabine and
vinorelbine in
patients with
non - small cell lung cancer previously treated with
cisplatin - based chemotherapy . -
pubmed
Thirty - nine
patients with advanced
non - small cell lung cancer , refractory or resistant to
platinum or
taxanes derivatives were treated on an out -
patient basis with
vinorelbine 25 mg / m2 intravenous ( I.V. ) -
pubmed
All 39
patients were assessable for
toxicity and 35 were assessable for response . -
pubmed
Clinical benefit response including improvement of
PS ,
dyspnea and
anorexia ,
pain and
cough reduction and cessation of
hemoptysis and
fever was observed in 10 % to 50 % of
patients . -
pubmed
Grade 3/4
neutropenia occurred only in 2 ( 5.2 % )
patients . -
pubmed
No
patient experienced grade 3/4
anaemia or
thrombocytopenia . -
pubmed
One
patient experienced grade 4
fatigue and stopped the treatment . -
pubmed
Nausea /
vomiting ,
fatigue ,
neurotoxicity ,
diarrhea and
fever were mild in the majority of
patients and did not result in any clinically significant problem . -
pubmed
BACKGROUND : The purpose of this historical cohort study was to compare the speech development of
children with three types of
cleft palate while controlling for some confounding factors . -
pubmed
METHODS : Subjects included 28
children with
bilateral cleft lip and palate (
BCLP ) , 74 with
unilateral cleft lip and palate (
UCLP ) , 33 with
isolated cleft palate (
ICP ) , and 168 normal control children . -
pubmed
Children with
cleft palate attended a speech clinic in Fukuoka , had attained adequate velopharyngeal function after palatoplasty carried out within 18 months after birth , and had no
syndromic diseases , persistent
hearing loss ,
mental retardation , or central nervous system problems . -
pubmed
RESULTS :
Children with
BCLP began using two - word sentences later than other
children ( 3 months , P<0.01 ) . -
pubmed
Children with
BCLP had lower verbal scores on the Wechsler Preschool and Primary Scale of Intelligence ( WPPSI ) than other children ( 12.4 - 14.9 points , P<0.01 ) . -
pubmed
CONCLUSIONS : The results of this research indicate the following : speech development of
children with
ICP and
UCLP was similar to that of normal children ; however , speech development of
children with
BCLP was delayed compared with other children with or without
cleft palate . -
pubmed
When the enzyme is provided by the infusion of normal plasma , these
patients remain free of
TTP symptoms for about three weeks . -
pubmed
Extent and severity of
atherosclerotic vascular disease in
patients undergoing coronary angiography -- the Kuwait Vascular Study . -
pubmed
The presence of
AND Cent Lec virus in rodent populations of the study area , which is responsible of
HPS cases in central Argentina , suggests that
human populations are at risk of
HPS disease , although there were not reported cases of this disease until
today . -
pubmed
BACKGROUND : The immediate result of successful revascularisation of the myocardium is the improvement of perfusion ( and in
patients with
depressed ventricular function , functional recovery is expected as an effect of coronary flow improvement ) . -
pubmed
Eighty - one percent of
patients had a history of
myocardial infarction , the number of stenosed main coronary arteries was 2.3 + /- 0.6 per
patient , and the left ventricle ejection fraction was 18 - 70 % ( mean 46 + /- 14 % ) . -
pubmed
Protection from
infectious bursal disease virus (
IBDV)-induced immunosuppression by immunization with a
fowlpox recombinant containing
IBDV - VP2 . -
pubmed
To facilitate clinical investigation of
metabolic acidosis , a high - performance liquid chromatographic method was adapted and validated for the chiral separation of
D -(- ) and L -(+)- lactic acid in
calf feces , rumen fluid and urine . -
pubmed
The ob
mouse has morbid
obesity and disordered breathing that is homologous to breathing of
obese humans . -
pubmed
Whole body plethysmography showed that PnO
neostigmine depressed breathing ( P & lt ; 0.001 ) in B6 and ob
mice and caused greater
respiratory depression in B6 than ob
mice ( P & lt ; 0.05 ) . -
pubmed
OBJECTIVES : To examine pharmacotherapy for
pain in a sample of 1,801
depressed older primary care
patients . -
pubmed
PARTICIPANTS : One thousand eight hundred one
patients aged 60 and older who met diagnostic criteria for
major depression or
dysthymia . -
pubmed
Oxcarbazepine (
Trileptal ) monotherapy dramatically improves quality of life in two
patients with
postherpetic neuralgia refractory to
carbamazepine and
gabapentin . -
pubmed
We conducted an open - label pilot clinical trial to evaluate the safety and efficacy of adding oral
azathioprine to the treatment regimen of 15
multiple sclerosis patients breaking through monotherapy with
interferon beta-1b . -
pubmed
Patients with recurrent
hernias were excluded if the initial repair was from a preperitoneal approach . -
pubmed
RESULTS :
Recurrences occurred in five
patients ( 0.47 % ) during a mean follow - up time of 23 months ( range : 2 - 47 ) . -
pubmed
First autochthonous case of
canine ocular onchocercosis in Germany . -
pubmed
The current authors conducted a retrospective study of 61
patients with both
emphysema of the upper zones and diffuse
parenchymal lung disease with
fibrosis of the lower zones of the lungs on chest computed tomography . -
pubmed
Dyspnoea on exertion was present in all
patients . -
pubmed
Pulmonary hypertension was present in 47 % of
patients at diagnosis , and 55 % during follow - up . -
pubmed
The purpose of this work was to develop an
abdominal aortic aneurysm (
AAA ) model that resembles
human aneurysms with potential for further growth , patent collateral vessels , and a predictable tendency to rupture , and that can be used in the development of new endoprostheses and implant training . -
pubmed
OBJECTIVE : The objective of this study was to establish the non - inferiority of an oral enzyme therapy ( Phlogenzym-(PE ) ) as compared to the non - steroidal anti - inflammatory drug ( NSAID )
diclofenac ( DC ) in
patients with
osteoarthritis (
OA ) of the hip . -
pubmed
METHODS : Ninety
patients presenting with painful episodes of
OA of the hip were treated for 6 weeks in one study centre in a phase III , randomised , double blind , parallel group trial . -
pubmed
For 71.1 % of the
PE patients and for 61.4 % of the DC
patients rates of good or very good global investigator assessments of efficacy were calculated ( test of non - inferiority : p = 0.0011 ) . -
pubmed
PE may well be recommended for the treatment of
patients with
osteoarthritis of the hip with signs of
inflammation as indicated by a high
pain level . -
pubmed
Feasibility of percutaneous nephrolithotomy under assisted local anaesthesia : a prospective study on selected
patients with
upper urinary tract obstruction . -
pubmed
METHODS : Twenty - four
patients with unilateral
renal obstruction due to
pelvic stones & gt ; or = 2.0 cm were enrolled in our study . -
pubmed
OBJECTIVE : To evaluate the safety and efficacy of vertebroplasty and kyphoplasty using the data presented in published clinical studies , with respect to
patient pain relief , restoration of mobility and vertebral body height , complication rate , and incidence of new adjacent
vertebral fractures . -
pubmed
Apoptosis , programmed cell
death , is a physiological phenomenon , necessary for normal function of every
organism . -
pubmed
OBJECTIVE : Imaging systems for
patients with
cleft palate typically are not portable , but are essential to obtain an audiovisual record of nasoendoscopy and otoscopy procedures . -
pubmed
Effect of
oxygen on health quality of life in
patients with
chronic obstructive pulmonary disease with transient
exertional hypoxemia . -
pubmed
RATIONALE : Ambulatory
oxygen improves acute exercise performance in
people with
chronic obstructive pulmonary disease (
COPD ) . -
pubmed
OBJECTIVES : We undertook a series of individual randomized controlled trials ( N - of-1 RCTs ) to measure the effect of
oxygen in
patients with
COPD who do not meet criteria for mortality reduction with long - term
oxygen therapy . -
pubmed
CONCLUSIONS : This study does not support the general application of long - term ambulatory
oxygen therapy for
patients with
COPD who do not meet criteria for mortality reduction with long - term
oxygen therapy . -
pubmed
Two weeks later the
patient underwent right parathyroidectomy that proved to be a parathyroid
adenoma . -
pubmed
This case should alert physicians to the association of multiple
brown tumors in
PHPT and that the presentation may be an aggressive one mimicking
metastasis ,
patients with
osteoporosis warrant at least
calcium profile to rule out a secondary cause . -
pubmed
Prevalence of
central nervous system cryptococcosis in
human immunodeficiency virus reactive hospitalized
patients . -
pubmed
A retrospective study was conducted on a total of 1,863
HIV reactive hospitalized patients suspected of
cryptococcal meningitis . -
pubmed
Prevalence of
cryptococcal meningitis in the total
HIV reactive cohort was 2.09 % . -
pubmed
We therefore studied the spectrum and outcome of
PHT in
children ( & lt;or=14 years of age ) over a period of 9 years . -
pubmed
CONCLUSIONS :
EHPVO and
cirrhosis are the two major causes of
PHT in
children . -
pubmed
CT measurement of trunk muscle areas in
patients with
chronic low back pain . -
pubmed
MATERIALS AND METHODS : In this study , we evaluated 36
patients with
chronic low back pain and 34 healthy
volunteers . -
pubmed
Comparative evaluation of the effects of statins on
human stem and
cancer cells in vitro . -
pubmed
Anticancer effects of statins were studied using karyotypically normal
human embryonic stem cells ( hESC ) (
HES3 ) , karyotypically abnormal hESC (
BG0IV ) ,
embryonal carcinoma (
NTERA-2 ) , ovarian (
TOV-112D ) and
colorectal cancer (
HT-29 ) cells . -
pubmed
Oral
polio vaccine (
OPV ) has been used safely and efficiently for more than 40 years in preventive medicine . -
pubmed
Immunodeficient recipients of
OPV can excrete
poliovirus vaccine strains for a long period and are at risk of developing flaccid
paralysis . -
pubmed
Histopathological analysis of infected
mouse lung tissues demonstrated severe
alveolitis ,
hemorrhaging , and spread of the virus throughout the entire lung . -
pubmed
Primary outcome measures were
deltamethrin residue and bioassay performance ( 60 minute knock - down and 24 hour mortality after a three minute exposure ) using a
strain of
Anopheles gambiae s.s . -
pubmed
Participants were assessed at the beginning of the longitudinal study and on average two years later by means of the California Verbal Learning Test ( CVLT ) and the Consortium to Establish a Registry for
Alzheimer ' s Disease - Neuropsychological Assessment Battery ( CERAD - NAB ) , a multidimensional cognitive test battery . -
pubmed
pyogenes is a strictly
human pathogen ( with the exception of a single
strain ) , the value of all animal models is limited . -
pubmed
Phage - resistance linked to cell heterogeneity in the commercial
strain Lactobacillus delbrueckii subsp . - pubmed
The aim of this work was to study the relationship between the cell morphological heterogeneity and the phage - resistance in the commercial
strain Lactobacillus delbrueckii subsp . - pubmed
A 1 - year - old
boy presented with the clinical manifestation of intractable complex partial
seizures and
development delay ; physical examination revealed two
fibrotic scars and
alopecia . -
pubmed
This study was done to evaluate left ventricular dimensions , systolic function , and the left ventricular myocardial performance index in
children with
obesity . -
pubmed
MEHTODS AND RESULTS : Thirty - three obese
children whose mean age was 9.8 + /- 2.4 years , weight was 61.3 + /- 20.8 kg ,
body mass index was 29.5 + /- 5.8 kg / m(2 ) , and percentage of actual weight to ideal
body weight for height ( % IBW ) was 170 + /- 25 % , underwent echocardiography for the assessment of left ventricular dimensions , and systolic and global functions . -
pubmed
There were 2 , 14 , and 17
children with mild ( & lt ; 140 % IBW ) , moderate ( 141 - 160 % IBW ) , and severe
obesity ( & gt ; 160 % IBW ) , respectively . -
pubmed
All were within the normal range , with the exception of two
children ( 6 % ) who had mild
left ventricular dilatation . -
pubmed
CONCLUSION : The left ventricular dimensions and systolic function in
children with
obesity were essentially normal . -
pubmed
The left ventricular myocardial performance index , which is an indicator for left ventricular global function , was found to be abnormal in 33 % of the
children , and may be used for the early detection of
left ventricular global dysfunction . -
pubmed
A Gram - negative , non - spore - forming , cream - coloured bacterial
strain ,
UM2 ( T ) , was isolated from an open
hexachlorocyclohexane (
HCH ) dump site at Ummari village in Lucknow , India . -
pubmed
The type
strain is
UM2 ( T ) (=
MTCC 9473(T ) = CCM 7545(T ) ) . -
pubmed
METHODS : The study group consisted of 24 postmenopausal
women ( mean age , 59.7 y ) who had various diseases , excluding
rheumatoid arthritis , and had been treated with 10 mg or more of oral
glucocorticoids (
prednisolone equivalent ) per day for more than 6 mo . -
pubmed
The chick embryo fibroblast infected by
Rous sarcoma virus in vitro acquires the capacity to produce the acid mucopolysaccharides which are found in the
tumors caused by this virus and which are also produced by
tumor cells in vitro . -
pubmed
Clinic - epidemiological evaluation of
ulcers in
patients with
leprosy sequelae and the effect of low level laser therapy on
wound healing : a randomized clinical trial . -
pubmed
The study objectives were to analyze the clinic - epidemiological characteristics of patients attended at one specialized dressing service from a
leprosy - endemic region of the Brazilian Amazon and to evaluate the effect of low level laser therapy ( LLLT ) on
wound healing of these
patients . -
pubmed
METHODS : Clinic - epidemiological evaluation of
patients with
leprosy sequelae was performed at the reference unit in sanitary dermatology of the state of Para in Brazil . -
pubmed
Fifty - one
patients with
ulcers related to
leprosy were evaluated , twenty - five of them were randomly assigned to a low level laser therapy group or a control group . -
pubmed
CONCLUSIONS :
Ulcers in patients with
leprosy remain a major source of economic and social losses , even many years after they have been cured of
M. - pubmed
The purpose of this study was to confirm this with a larger sample size and to establish whether raised IMT in black
stroke - free
individuals is associated with increased
carotid plaque . -
pubmed
UNLABELLED : In a study of 2005 institutionalized older
people , use of oral
bisphosphonates was associated with a 27 % reduction in risk of
death compared to non - users after adjusting for potential confounders . -
pubmed
METHODS : Two thousand and five institutionalized older
people ( mean age 85.7 years ) were assessed at baseline and followed up for
hip fracture and
death for at least 5 years . -
pubmed
A prospective study of macular thickness in amblyopic
children with unilateral
high myopia . -
pubmed
PURPOSE : To compare macular thickness of the normal fellow eye to that of the amblyopic eye using optical coherence tomography ( OCT ) in
children with unilateral
high myopia . -
pubmed
CONCLUSIONS : Amblyopic
children with
unilateral high myopia tend to have a thicker fovea and thinner inner and outer macula in the amblyopic eye compared to the normal fellow eye . -
pubmed
The findings indicate that anatomic changes may be present in the retinas of amblyopic
children with unilateral high
myopia . -
pubmed
Another possible limitation is that the ARCC trial included
patients with advanced
renal cell carcinoma , and thus it can not be conclusively determined how our findings would apply to
patients with less advanced disease . -
pubmed
Amitriptyline and
prochlorperazine inhibit proinflammatory mediator release from
human mast cells : possible relevance to
chronic fatigue syndrome . -
pubmed
MATERIAL AND METHODS : This study involved 40 pregnant
women ; normal ( n = 20 ) , and
PE ( n = 20 ) , the latter of who were classified into ( i ) mild ( n = 10 ) and severe
PE ( n = 10 ) ; ( ii )
PE with
SGA ( n = 7 ) and without
SGA ( n = 13 ) . -
pubmed
Four weeks after surgery , new
scar formation or progression of the preoperative
scar at the site of access were seen in 14 of 29 ( 48.3 % )
patients who were treated with one - stage dilation whereas only 2 of 19 ( 11.0 % )
patients who were treated with gradual dilation developed new
scarring at the access site ( P=0.007 ) . -
pubmed
This study aimed at investigating the survival rate and prognostic factors of
laryngeal carcinoma patients in the absence of the use of laryngectomy , radiotherapy , and chemotherapy . -
pubmed
In
laryngeal carcinoma patients with no surgery , radiotherapy or chemotherapy , the factors affecting the survival rates include primary site , pathological grade , T - stage , N - stage , and clinical stage , and of them , T - stage and N - stage are the independent prognostic factors . -
pubmed
We show that : ( 1 ) the sequence variant spectrum of these two individuals ' DNA sequences is largely comparable to existing non - supercentenarian genomes ; ( 2 ) the two individuals do not appear to carry most of the well - established
human longevity enabling variants already reported in the literature ; ( 3 ) they have a comparable number of known
disease - associated variants relative to most human genomes sequenced to - date ; ( 4 ) approximately 1 % of the variants these individuals possess are novel and may point to new genes involved in exceptional longevity ; and ( 5 ) both individuals are enriched for coding variants near longevity - associated variants that we discovered through a large genome - wide association study . -
pubmed
PATIENTS AND METHODS : The study involved 592
children with radiographically confirmed
CAP whose respiratory secretion samples were tested using the Luminex xTAG Respiratory Virus Panel Fast assay , which simultaneously detects
influenza A virus ,
influenza B virus ,
respiratory syncytial virus (
RSV)-A and -B ,
parainfluenzavirus-1 , -2 , -3 , and -4 , adenovirus ,
human metapneumovirus ,
coronaviruses 229E ,
NL63 ,
OC43 , and
HKU1 ,
enterovirus / rhinovirus , and bocavirus . -
pubmed
RESULTS : A total of 435 children ( 73 5 % ) were positive for at least one virus : the most frequently detected was
RSV , which was found in 188 ( 31 7 % ) , followed by rhinovirus ( n = 144 , 24 3 % ) , bocavirus ( n = 60 , 10 1 % ) ,
influenza viruses ( n = 57 , 9 6 ) , and
hMPV ( n = 49 , 8 2 % ) . -
pubmed
CONCLUSIONS : The findings of this study highlight the importance of respiratory viruses ( mainly
RSV and rhinovirus ) in children with
CAP and show the characteristics of both the single
infections and co -
infections associated with the disease . -
pubmed
The
saponin of
red ginseng protects the cardiac myocytes against
ischemic injury in vitro and in vivo . -
pubmed
Adult
rat heart ischemia , which was induced by ligation of the left anterior descending coronary artery , was employed for the in vivo analysis . -
pubmed
Transcatheter closure of perimembranous
ventricular septal defects : initial
human experience with the Amplatzer membranous VSD occluder 2 . -
pubmed
Anxiety ,
depression , and
pain in
burning mouth syndrome : first
chicken or egg ? -
pubmed
OBJECTIVE : The aim of this study was to evaluate the relationship between
pain ,
depression , and
anxiety in
BMS and healthy
patients in order to hypothesize a possible underlying pathogenetic model . -
pubmed
METHODS : Fifty - three
patients with
BMS and 51 healthy
volunteers matched for sex and age were enrolled . -
pubmed
RESULTS : BMS
patients and healthy volunteers showed a statistically significant difference in psychiatric features : Regression analysis showed that
pain is affected by
depression ( R = 0.373 ; R(2 ) corrected = 0.123 ; F = 8.563 ; P & lt ; .005 ) , and
depression is affected by
anxiety ( R = 0.512 ; R(2 ) corrected = 0.248 ; F = 18.519 ; P & lt ; .001 ) . -
pubmed
CONCLUSIONS : We may hypothesize that
anxiety could determine a secondary demoralization in
BMS patients (
depression ) and
depressive symptoms could contribute to
pain , accordingly . -
pubmed
BACKGROUND : An inherited basis for
congenital extrahepatic portosystemic shunts (
EHPSS ) has been demonstrated in several small
dog breeds . -
pubmed
RESULTS : Data of 135 client owned
dogs diagnosed with
EHPSS at the Faculty of Veterinary Medicine of Utrecht University from 2001 - 2010 were retrospectively analyzed . -
pubmed
CONCLUSION : The remarkable similarity of phenotypic variation in many
dog breeds may indicate common underlying genes responsible for
EHPSS across breeds . -
pubmed
Since there are similarities between the pathogenesis of
preeclampsia and
atherosclerosis we hypothesised an increased accumulation of oxLDL at the materno - foetal and foeto - foetal interface within the placental tissue of preeclamptic
women compared to women with normotensive pregnancies ( controls ) . -
pubmed
Histopathological features of
bisphosphonate - associated
osteonecrosis : findings in
patients treated with partial mandibulectomies . -
pubmed
The present study investigated the histopathologic and radiographic features of stage 3
bisphosphonate - associated
osteonecrosis of the jaw (
BAONJ ) in
patients who were treated with partial mandibulectomies . -
pubmed
Bisphosphonates had been orally administered to 10
patients with
osteoporosis and intravenously administered to 1
patient with metastatic
carcinoma . -
pubmed
On radiographic images , massive
osteolysis and periosteal bone formations were conspicuous , and a thin mandibular cortical width was observed in 5 of 10
osteoporosis patients despite the previous use of
bisphosphonate . -
pubmed
Evaluation of the pathogenesis of
meningitis caused by
Streptococcus suis sequence type 7 using the
infection of
BV2 microglial cells . -
pubmed
Streptococcus suis is an important agent of
swine and human meningitis . -
pubmed
METHODOLOGY : The clinical data of 65 adult
patients with
CCs at the Second Affiliated Hospital of Chongqing Medical University between 2007 and 2011 were analyzed retrospectively . -
pubmed
Forty - six
patients underwent extrahepatic bile duct ( EHBD ) dilatation resection plus Roux - en - Y hepaticojejunostomy ( HJ ) , 16
patients underwent partial hepatectomy plus EHBD resection plus Roux - en - Y HJ , 1 patient underwent partial hepatectomy , 1 patient underwent external drainage only , and 1 patient underwent reconstruction of hepatoenteric anastomosis by excision of
stenosis . -
pubmed
An 83 - year - old
man suddenly developed
numbness in his bilateral perioral area and right hand . -
pubmed
The
patient was diagnosed as having
cheiro - oral syndrome with bilateral perioral sensory disturbance , probably due to unilateral pontine tegmental
hemorrhage . -
pubmed
In this report we use both an established neuronal cell line model and an
embryonic stem cell - based system to examine
human neuronal innate immunity and responses to neurotropic
alphavirus infection in
cultured cells . -
pubmed
Two - legged hopping in place in sync with an auditory cue ( 2.3 , 3.0 Hz ) was studied in a group of six
individuals with expressive language impaired
ASD (
ELI - ASD ) and an age - matched control group . -
pubmed
A
strain of Gram - staining - negative , aerobic , non - flagellated , non - gliding and rod - shaped bacteria , designated
WS - MY3 ( T ) , was isolated from a brown algae reservoir in South Korea . -
pubmed
The major polar lipids of
strain WS - MY3(T ) were
phosphatidylethanolamine and two unidentified lipids . -
pubmed
The DNA G+C content of
strain WS - MY3(T ) was 37.3 mol% and its DNA - DNA relatedness values with
F. - pubmed
The type
strain is
WS - MY3(T ) ( = KCTC 32328(T ) = CECT 8286(T ) ) . -
pubmed
The 3 - D morphological features extracted from breast MRI were used to analyze the malignant likelihood of
tumor from ninety - five solid breast masses ( 44 benign and 51 malignant ) of 82
patients . -
pubmed
Behavioural sleep problems in
children with
attention - deficit / hyperactivity disorder (
ADHD ): protocol for a prospective cohort study . -
pubmed
INTRODUCTION :
Children with
attention - deficit / hyperactivity disorder (
ADHD ) commonly experience behavioural sleep problems , yet these difficulties are not routinely assessed and managed in this group . -
pubmed
Intermedin in the paraventricular nucleus attenuates cardiac sympathetic afferent reflex in chronic
heart failure rats . -
pubmed
Cardiac sympathetic afferent reflex ( CSAR ) is enhanced in chronic
heart failure (
CHF )
rats . -
pubmed
The aim of this study is to determine the effect of IMD in the PVN on CSAR and its related mechanisms in
CHF rats . -
pubmed
METHODOLOGY / PRINCIPAL FINDINGS :
Rats were subjected to left descending coronary artery ligation to induce
CHF or sham - operation ( Sham ) . -
pubmed
Schistosomes are parasitic worms that can survive in the hostile environment of the
human bloodstream where they appear refractory to both immune elimination and
thrombus formation . -
pubmed
By degrading host inflammatory signals like
ATP , and pro - thrombotic signals like
ADP , these parasite enzymes may minimize host immune responses , inhibit
blood coagulation and promote
schistosome survival . -
pubmed
INTRODUCTION AND OBJECTIVES : There have been no studies conducted in the past that focus on the significance of
congestive heart failure in
patients with
prosthetic valve endocarditis . -
pubmed
We studied the incidence of
congestive heart failure in
patients with
prosthetic valve endocarditis and analyzed its profile . -
pubmed
In this study , we addressed the prognostic significance of
heart failure in
patients with
prosthetic valve endocarditis and analyzed its outcome based on chosen therapeutic strategies . -
pubmed
We compared the profiles of patients with
prosthetic valve endocarditis based on the presence of
heart failure , and performed a multivariate logistic regression model to establish the prognostic significance of
heart failure in
patients with
prosthetic valve endocarditis and identified the prognostic factors of in - hospital mortality in these
patients . -
pubmed
RESULTS : Persistent
infection ( odds ratio=3.6 ; 95 % confidence interval , 1.9 - 6.9 ) and
heart failure ( odds ratio=3 ; 95 % confidence interval , 1.5 - 5.8 ) are the strongest predictive factors of in - hospital mortality in
patients with
prosthetic valve endocarditis . -
pubmed
Patients indicated for MACI in this follow - up were 13 to 65 years of age , although they were excluded if they had a
BMI & gt;35 kg / m(2 ) , had undergone prior extensive meniscectomy , or had ongoing progressive
inflammatory arthritis . -
pubmed
METHODS : Male
Wistar streptozotocin - diabetic rats ( and age - matched controls ) were examined 2 ( early ) and 8 weeks ( late ) after the induction of
diabetes . -
pubmed
Anthrax is a non - contagious
infectious disease ; it primarily affects herbivores , but all mammals , including
humans , can be affected . -
pubmed
Humans may contract
anthrax directly or indirectly from infected animals . -
pubmed
Veterinary surveillance systems , providing information about animal and
human cases , should increase the efficacy of the animal
anthrax management in order to protect population . -
pubmed
In this paper we propose a new , detailed classification of
anthrax outbreaks , based on the source of the
infection and the risk level for
humans . -
pubmed
They were divided into three groups , Group I ( control ) from healthy children ( n = 6 ) , Group II from acyanotic
CHD children ( n = 12 ) and Group III from cyanotic
CHD children ( n = 12 ) . -
pubmed
METHODS : A cohort of 208
patients cumulatively treated between June 2008 and December 2012 qualified for study inclusion , each undergoing total - gland cryoablation for
prostate cancer . -
pubmed
CONCLUSIONS : Saturated prostate cryoablation by reducing APVC would be beneficial for
cancer control without compromising
patient safety . -
pubmed
A partial resolution of
AP could manifest as complex
human diseases , and the inability to resolve
AP may play a role in speciation . -
pubmed
Predictive factors for occult contralateral
carcinoma in
patients with unilateral
papillary thyroid microcarcinoma by preoperative ultrasonographic and pathological features . -
pubmed
BACKGROUND : The surgical extent and indication for treatment in
patients with
papillary thyroid microcarcinoma (
PTMC ) remain a controversial issue . -
pubmed
The aim of this study was to investigate the predictive factor for contralateral occult
carcinoma in
patients with unilateral
PTMC by preoperative ultrasonographic and pathological features . -
pubmed
METHODS : Of the total
patients who underwent thyroidectomy , 455
patients with
PTMC confined to one unilateral lobe as diagnosed using preoperative ultrasonography ( US ) were enrolled in the study . -
pubmed
All
patients underwent preoperative US review to investigate the US features of
PTMC such as laterality , location , size , internal component , echogenicity , margin , calcification shape , multifocality , bilaterality , extrathyroidal extension , and location with respect to the trachea . -
pubmed
RESULTS : Of the total of 455
patients who underwent total thyroidectomy for preoperatively detected unilateral
PTMC , 71
patients ( 15.6 % ) had contralateral occult
carcinoma . -
pubmed
Clinicopathological characteristics did not significantly differ between
patients with and without contralateral occult
carcinoma . -
pubmed
Multivariate analysis showed that the absence of a well - defined margin and the presence of a probably benign nodule in the contralateral lobe were independent predictive factors for contralateral occult
carcinoma in
patients with unilateral
PTMC in preoperative US images . -
pubmed
CONCLUSION : We demonstrated that an absence of a well - defined margin and the presence of a probably benign nodule in the contralateral lobe were independent predictive factors for contralateral occult
carcinoma in
patients with unilateral
PTMC in preoperative US . -
pubmed
Usefulness and safety of endoscopic retrograde cholangiopancreatography in
children with
pancreaticobiliary maljunction . -
pubmed
BACKGROUND : To assess the diagnostic ability and safety of endoscopic retrograde cholangiopancreatography ( ERCP ) in in - depth preoperative examination of
children patients with
pancreaticobiliary maljunction (
PBM ) . -
pubmed
METHODS : In 63
patients with a definite diagnosis of
PBM , the ability to visualize the bile and main pancreatic ducts was compared between ERCP , which was performed in 63
patients with a definite diagnosis of PBM , and magnetic resonance cholangiopancreatography ( MRCP ) , which was performed before ERCP in 29
patients . -
pubmed
As complications ,
hyperamylasemia developed in 12
patients ( 19 % ) , but no other severe complications such as
pancreatitis were observed . -
pubmed
CONCLUSIONS : ERCP as part of an in - depth preoperative examination of
children with
PBM is useful and safe . -
pubmed
Tuberculosis should be suspected in
patients presenting with multiple
bone lesions , especially in endemic areas . -
pubmed
CONCLUSION : Neutrophil to lymphocyte ratio value may be used as a novel marker that is easily administered in
patients with
nasal polyps and obtained with low - cost tests . -
pubmed
OBJECTIVE : More than 85 % of
patients with
end - stage renal disease start dialysis through a tunneled dialysis catheter ( TDC ) for long periods while their
arteriovenous fistula or vascular access graft ( arteriovenous graft [ AVG ] ) matures . -
pubmed
Because TDCs are associated with a high risk of complications , including
death and
infection , use of an AVG that can be cannulated safely immediately after implantation may reduce morbidity in these
patients by allowing earlier TDC removal . -
pubmed
OBJECTIVE : To evaluate the correlation between diaphragm thickness assessed by ultrasound ( US ) with respiratory function tests and the diaphragm motor responses , in
patients with
amyotrophic lateral sclerosis (
ALS ) . -
pubmed
METHODS : 42 consecutive
ALS patients were studied ( 11 with bulbar - onset ) , excluding
patients with marked
orofacial paresis . -
pubmed
MATERIALS AND METHODS : Thirty - five
patients with
degenerated spondylolisthesis ,
discogenic pain , and
kyphoscoliosis were examined . -
pubmed
CONCLUSION : The eFACE is a reliable , reproducible , and straightforward digital clinical measure with which to assess facial function and disfigurement in
patients with
facial paralysis . -
pubmed
We enrolled 36
patients with severe
sepsis . -
pubmed
Other perfusion variables failed to predict vasopressor requirement in
patients with severe
sepsis . -
pubmed
The aim of this study was to assess the status of the iliopsoas muscle and other flexors and extensors of the hip in long - term follow - up with magnetic resonance imaging after complete iliopsoas tenotomy in
patients with unilateral
DDH treated with open reduction with a medial approach . -
pubmed
METHODS : The study included 20
patients who underwent open reduction with a medial approach for unilateral
DDH and had long - term follow - up . -
pubmed
hydroxy ,
epoxy and
dihydroxy FA in
obese subjects with persistent low - grade
inflammation . -
pubmed
We aimed to evaluate levels of inflammatory markers and blood
oxylipins in obese
subjects before and after
weight reduction . -
pubmed
Interestingly , in
subjects with low- grade
inflammation several AA - derived
oxylipins (
5 - , 8 - , 12 - hydroxyeicosatetraenoic acids (
HETE ) ) were significantly higher compared to subjects with no
inflammation before
weight reduction and significantly reduced after
weight reduction . -
pubmed
Comment on " Exposure - response modeling of
non - cancer effects in
humans exposed to Libby Amphibole Asbestos ; update " by Benson et al . -
pubmed
Given the dismal outcome of our case and previously reported cases , we propagate the implementation of targeted therapies to newly diagnosed
patients with
acute myeloid leukemia t(2;3 ) . -
pubmed
Here , we show that
TLT develops as newly formed lymphoid tissue in the colon following dextran sulphate
sodium induced
colitis in
C57BL / 6 mice , where it can be distinguished from the preexisting colonic patches and solitary intestinal lymphoid tissue . -
pubmed
METHODS : A total of 336
patients with
heart valve disease were included in this study , including 167 with
AF and 169 with
sinus rhythm . -
pubmed
AIMS / HYPOTHESIS :
Women with a history of
gestational diabetes mellitus (
GDM ) have raised liver
triacylglycerol . -
pubmed
The aim of this work was to examine liver
triacylglycerol accumulation in
women with
GDM and the effect of modest energy restriction . -
pubmed
METHODS : Sixteen
women with
GDM followed a 4 week diet ( 5 MJ [ 1200 kcal]/day ) . -
pubmed
Twenty - six
women who underwent standard antenatal care for
GDM ( matched for age , BMI , parity and ethnicity ) were used as a comparator group . -
pubmed
RESULTS : Fourteen
women , who completed the study , achieved a
weight loss of 1.6 + - 1.7 kg over the 4 week dietary period . -
pubmed
CONCLUSIONS / INTERPRETATION : Liver
triacylglycerol in
women with
GDM was not elevated , unlike observations in non - pregnant
women with a history of
GDM . -
pubmed
A Canola Oil - Supplemented Diet Prevents
Type I Diabetes - Caused
Lipotoxicity and
Renal Dysfunction in a
Rat Model . -
pubmed
We investigated the effect of a
canola oil - supplemented diet on the metabolic state and
diabetic renal function of a
type I diabetes experimental model . -
pubmed
Male
Sprague - Dawley rats were randomly divided into four groups : ( 1 ) normoglycemic+chow diet , ( 2 ) normoglycemic+a canola oil - supplemented chow diet , ( 3 )
diabetic+chow diet , and ( 4 )
diabetic+a canola oil - supplemented chow diet . -
pubmed
Diabetic rats fed with a canola oil - supplemented diet had higher
body weights , were less
hyperphagic , and their mesenteric , retroperitoneal , and epididymal fat pads weighed more than
diabetic rats on an unsupplemented diet . -
pubmed
Xylose - assimilating pathway was constructed in a
d - lactic acid producing
Pediococcus acidilactici strain and evolutionary adapted to yield a co - fermentation
strain P. - pubmed
Efficacy In Vitro of
Caffeine and
Valproic Acid on
Patient - Derived Undifferentiated
Pleomorphic Sarcoma and
Rhabdomyosarcoma Cell Lines . -
pubmed
We subsequently established
patient - derived cell lines from
undifferentiated pleomorphic sarcoma (
UPS ) and
rhabdomyosarcoma (
RMS ) , both of which are
recalcitrant cancers . -
pubmed
MATERIALS AND METHODS : In the present study , we tested
CAF and
VPA and their combination on the two
patient - derived
sarcoma cell lines . -
pubmed
Tumour mutation status and sites of
metastasis in
patients with
cutaneous melanoma . -
pubmed
METHODS : Prospective cohort of
patients with a histologically confirmed primary
cutaneous melanoma at three tertiary referral centres in Melbourne , Australia from 2010 to 2015 . -
pubmed
RESULTS : Of 1048
patients , 306 ( 29 % ) developed
metastasis over a median 4.7 year follow - up period . -
pubmed
Overall , 113 serum samples were also collected from the
dogs living in these areas ; suspecting to be risk factors for this
infection . -
pubmed
Infection rate was significantly more in
cows with the history of
abortion . -
pubmed
CONCLUSION : The results show a high seroprevalence of the
infection and possibly the role of the
dogs in horizontal transmission of the
infection . -
pubmed
To the best of the authors ' knowledge , the case presented is the first report of
ACC in a
patient with
CDRIE due to
infection of pacemaker leads . -
pubmed
The wearable cardioverter defibrillator ( WCD ) is a temporary treatment option for
patients with potentially reversible risk of
sudden cardiac death . -
pubmed
In most but not all pregnant
patients presenting with a new or worsening
neurological abnormality , the risks intrinsic to the disease will outweigh the risks of imaging . -
pubmed
Systolic time ratio measured by impedance cardiography accurately screens
left ventricular diastolic dysfunction in
patients with
arterial hypertension . -
pubmed
The IMPEDDANS study aims to assess the usefulness of ICG for the screening of
left ventricular diastolic dysfunction (
LVDD ) in
patients with
HT . -
pubmed
Methods :
Patients with
HT were assessed by echocardiography and ICG . -
pubmed
Conclusion : The ICG derived value of STR allows the accurate screening of
LVDD in
patients with
HT . -
pubmed
However , the progression - free survival and overall survival in
patients with
GA is less than in
patients with diffuse
astrocytomas . -
pubmed
Differences in the histological pattern , immunohistochemical and molecular - genetic profiles , survival of
patients with
GA and
diffuse astrocytomas GII are shown there . -
pubmed
A clinical case of a
patient with transformation of a diffuse
astrocytoma in
GA ( GIII ) and then into a
secondary glioblastoma is presented . -
pubmed
Genome - wide association study and heritability estimate for
ectopic ureters in Entlebucher mountain
dogs . -
pubmed
There was no single outstanding SNP associated with the phenotype , and the association signals were not close to known genes involved in
human congenital anomalies of the kidney or lower urinary tract . -
pubmed
Gender Identity and Sexual Function in 46,XX
Patients with
Congenital Adrenal Hyperplasia Raised as Males . -
pubmed
In
individuals with
congenital adrenal hyperplasia (
CAH ) and 46,XX karyotype ,
androgens produced by the adrenal glands during the intrauterine development promote
virilization of the genitals , which may even result in the development of a well - formed penis . -
pubmed
Additional strategies may be necessary to improve survival among female
cardiac arrest patients . -
pubmed
INTRODUCTION : The aim of this systematic review is to investigate the effects of perioperative intravenous administration of
MgSO4 on
postoperative pain , analgesic consumption and adverse effects in
patients undergoing orthopedic surgery . -
pubmed
We evaluated clinical outcomes , comparing postoperative
pain scores , cumulative analgesic consumption , time to first analgesia , and adverse effects between orthopedic surgery
patients with and without the administration of
MgSO4 . -
pubmed
However , intravenous
MgSO4 administration should be considered as a strategy to relieve
postoperative pain in orthopedic surgery
patients . -
pubmed
Patients from the mini - AVR group reported less
postoperative pain . -
pubmed
In conclusion , a close cooperation between the various disciplines in the pre- and postoperative management is essential in order to optimize the timing and outcome of
patients with
UC . -
pubmed
Humanized
Mouse Model Mimicking Pathology of
Human Tuberculosis for in vivo Evaluation of Drug Regimens . -
pubmed
Although they were employed for analyzing
tuberculosis (
TB ) disease , there is little data on the spatial organization and cellular composition of
human immune cells in
TB granuloma pathology in this model . -
pubmed
We demonstrate that
human immune system
mice , generated by transplanted
human fetal liver derived hematopoietic stem cells develop a continuum of
pulmonary lesions upon
Mycobacterium tuberculosis aerosol
infection . -
pubmed
We consider this model instrumental for deeper understanding of
human specific features of
TB pathogenesis and of particular value for the pre - clinical drug development pipeline . -
pubmed
Suspected
citrus leprosis symptoms on leaves and fruits of
sweet oranges (
Citrus sinensis ( L. ) Osb . ) -
pubmed
To confirm the visual identification , leaves and fruits from Valencia
sweet orange exhibiting typical lesions of
leprosis were collected from several locations in the departments of Casanare ( Yopal , Aguazul ) and Meta ( Guamal , Villavicencio , and Cumaral ) . -
pubmed
These several lines of evidence confirmed that the symptoms observed in
sweet oranges at Meta and Casanare are due to the
infection by
CiLV - C . To our knowledge , this is the first report of this virus in Colombia . -
pubmed
Molecular analysis of clonally related
Salmonella Typhi recovered from epidemiologically unrelated cases of
typhoid fever , Brazil . -
pubmed
This study demonstrates that
propiconazole can induce
hypopigmentation in
zebrafish , disrupt mitochondrial bioenergetics , and can alter locomotor activity . -
pubmed
BACKGROUND :
Lymphopenia has been observed in severe
pandemic influenza A / H1N1 in developed countries . -
pubmed
This study aimed to observe change of lymphocyte counts in patients with severe
pandemic influenza A / H1N1 and to investigate the correlation of
lymphopenia and severe
pandemic influenza A / H1N1 . -
pubmed
CONCLUSIONS :
Lymphopenia along with other clinical parameters may be helpful in early differential diagnosis of severe
pandemic influenza A / H1N1 . -
pubmed
In this study , we showed that miR-103 was deregulated in
osteoarthritis patients . -
pubmed
Regulation of miR-103 expression in
human chondrocytes may be an effective treatment for
osteoarthritis . -
pubmed
Effects of
polyploidy on the coordination of gene expression between organellar and nuclear genomes in
Leucanthemum Mill . -
pubmed
Mesenchymal stem cell - derived exosomes ameliorate erection by reducing oxidative stress damage of corpus cavernosum in a
rat model of
artery injury . -
pubmed
With similar potency compared with the stem cell therapy and other unique advantages , IC injection of MSC- Exos could be an effective treatment to ameliorate erectile function in a
rat model of
arterial injury . -
pubmed
BACKGROUND : Inadvertent perioperative
hypothermia is common in
patients undergoing off - pump coronary artery bypass grafting ( OPCAB ) . -
pubmed
Patients were divided into 4 groups based on body temperature at the time of intensive care unit admission after surgery ( moderate - to - severe
hypothermia , < 35.5 C ; mild
hypothermia , 35.5 C-36.5 C ;
normothermia , 36.5 C-37.5 C ; and
hyperthermia , > = 37.5 C ) . -
pubmed
Patients who were
hypothermic at postoperative intensive care unit admission but attained normothermia thereafter were at a lower risk of all - cause mortality compared to
patients who did not regain normothermia ( adjusted hazard ratio , 0.631 ; 95 % confidence interval , 0.453 - 0.878 ) , while they were still at a higher risk of all - cause mortality than those who were consistently normothermic ( adjusted hazard ratio , 1.435 ; 95 % confidence interval , 1.090 - 1.890 ) . -
pubmed
Cell - free DNA ( cfDNA ) and nucleosomes are two biomarkers of cell
death and neutrophil extracellular trap formation that are increased in
dogs with
sepsis , immune - mediated
haemolytic anaemia ,
cancer and following
trauma and have diagnostic and prognostic values . -
pubmed
Following this , the
cytotoxicity of these compounds was evaluated against four
cancer cell lines (
human hepatoma cell
HepG-2 ,
human lung cancer cell
A549 ,
human breast cancer cell
MCF-7 , and
human colon cancer cell
HCT-116 ) and one normal cell line (
human gastric epithelial cell line -
GES - 1 ) . -
pubmed
We hope this exoskeleton device can help
stroke patients with loss of function in the upper extremities to resume motor activities in order to maintain activities of daily living . -
pubmed
Previous in vitro studies showed that EVs purified from normal
mouse AML12 hepatocytes ( " EVNorm " ) attenuate the pro - fibrogenic activities of activated hepatic stellate cells ( HSCs ) , a principal
fibrosis - producing cell type in the liver . -
pubmed
RNA sequencing ( RNA - seq ) revealed that EVNorm therapy of
mice receiving
CCl4 for 5 weeks resulted in significant differences [ false discovery rate ( FDR ) & lt;0.05 ] in expression of 233
CCl4 - regulated hepatic genes and these were principally associated with
fibrosis , cell cycle , cell division , signal transduction , extracellular matrix ( ECM ) , heat
shock , cytochromes , drug detoxification , adaptive immunity , and membrane trafficking . -
pubmed
These findings show that EVs from
human or
mouse hepatocytes regulate toxin - associated gene expression leading to therapeutic outcomes including suppression of fibrogenesis ,
hepatocyte damage , and/or
inflammation . -
pubmed
Multidrug - Resistant ( MDR ) and Extensively Drug Resistant ( XDR )
Acinetobacter baumannii ( Ab ) represent a serious cause of healthcare - associated
infections worldwide . -
pubmed
Two sets of trials , one with 12 early - to - intermediate maturing and the other with 13 intermediate - to - late maturing hybrids , improved for tolerance to multiple stresses common in farmers ' fields in eastern Africa ( drought , northern
corn leaf blight , gray leaf
spot ,
common rust ,
maize streak virus ) , were evaluated on - farm under smallholder farmers ' conditions in a total of 42 and 40 environments ( site - year - management combinations ) , respectively , across Kenya , Uganda , Tanzania and Rwanda in 2016 and 2017 . -
pubmed
In this study , we aimed to describe in detail respiratory tract complications as the most prominent clinical feature among
agammaglobulinemic patients . -
pubmed
Bronchiectasis was found in 13
patients undergoing HRCT ( 44.8 % ) . -
pubmed
In
patients with
IRIDA , the
iron uptake in the intestine is remarkably reduced , and
iron deficiency anemia (
IDA ) develops . -
pubmed
Cutibacterium acnes and
autoinflammatory bone disease : Case series of three patients . -
pubmed
Multimodal MALDI Imaging Mass Spectrometry Reveals Spatially Correlated Lipid and Protein Changes in
Mouse Heart with
Acute Myocardial Infarction . -
pubmed
In this work , we demonstrate an application of multimodal chemical imag - ing using matrix - assisted laser desorption / ionization mass spectrometry ( MALDI - MS ) which provided comprehensive molecu - lar information in situ within the same
mouse heart tissue sections with
myocardial infarction . -
pubmed
This methodology allowed us to interpret the lipid and protein molecular pathology of the very same infarcted region in a
mouse model of
myocardial infarction . -
pubmed
RESULTS : Among 105
patients , 14 ( 13.3 % ) developed
ORN . -
pubmed
The SUVmax of the periodontal region in
patients with
ORN ( 3.35 + - 1.23 ) was significantly higher than
patients without ORN ( 1.92 + - 0.66 ) ( P < .01 ) . -
pubmed
The corresponding CT stage of
periodontitis in
patients with
ORN was significantly higher ( 2.71 + -0.47 ) than
patients without ORN ( 1.80 + -0.73 ) ( P < .01 ) . -
pubmed
MATERIALS AND METHODS : We performed retrospective CGM and blood tests on 189
outpatients with
impaired glucose tolerance ( n = 22 ) ,
type 1 diabetes mellitus (
T1DM , n = 67 ) , or
type 2 diabetes mellitus (
T2DM , n = 100 ) . -
pubmed
New approaches to complement vaccination are needed to combat the spread of
SARS - CoV-2 and stop
COVID-19 related
deaths and long - term medical complications . -
pubmed
First study of safety and tolerability of
3,4 - methylenedioxymethamphetamine - assisted psychotherapy in
patients with
alcohol use disorder . -
pubmed
BACKGROUND :
3,4 - methylenedioxymethamphetamine (
MDMA ) therapy has qualities that make it potentially well suited for
patients with
addictions , but this has never been explored in a research study . -
pubmed
This is the first
MDMA addiction study , an open - label safety and tolerability proof - of - concept study investigating the potential role for
MDMA therapy in treating
patients with
alcohol use disorder (
AUD ) . -
pubmed
AIMS : This study aimed to assess if
MDMA - assisted psychotherapy can be delivered safely and can be tolerated by
patients with
AUD post detoxification . -
pubmed
METHODS : Fourteen
patients with
AUD completed a community
alcohol detoxification and received an eight - week course of recovery - based therapy . -
pubmed
Describe the incidence of
invasive pneumococcal disease (
IPD ) in serotypes with reduced antibiotic sensitivity to
penicillin (
RAS - Pen ) in adults over 59 years of age and its association with childhood anti -
pneumococcal vaccination coverage ( CVC ) and community consumption of
beta - lactam . -
pubmed
The non -
PCV13 strains that increased the most at the end of the period were 6C , 11A and 15A. -
pubmed
The incidence of
IPD due to
PCV13 with RAS - Pen at > 59 years was decreasing and was associated with
CVC . -
pubmed
Impact of 6- versus 12 - month dual antiplatelet therapy on clinical prognosis in
patients with high
bleeding risk : Insights from the 4 - year results of the I LOVE IT 2 study . -
pubmed
BACKGROUND : The optimal DAPT duration after percutaneous coronary intervention ( PCI ) in
HBR patients is unclear . -
pubmed
Prevalence and prognosis of
HBR patients were explored , and clinical outcomes of HBR
patients who underwent 6- versus 12 - month
DAPT were compared . -
pubmed
HBR
patients were associated with a higher risk of BARC type 3 or 5
bleeding ( 2.95 vs. 1.52 % , p = .03 ) , NACE ( 31.82 vs. 25.99 % , p = .01 ) , all - cause
death ( 5.68 vs. 3.13 % , p = .008 ) and
stroke ( 9.09 vs. 3.83 % , p < .001 ) than non - HBR
patients at 4 years . -
pubmed
There were no significant differences in BARC type 3 or 5
bleeding ( 3.07 vs. 2.76 % , p = 1.00 ) or NACE rate ( 31.9 vs. 33.8 % , p = .72 ) between
patients who underwent 6- and 12 - month
DAPT . -
pubmed
CONCLUSIONS : HBR
patients are at a higher risk of long - term
bleeding and
ischemic events than non - HBR
patients . -
pubmed
Four
patients ( 4.7 % ) developed late complications ( Port site
hernia 2 ;
internal hernia 1 ;
Stomal ulcer 1 ) . -
pubmed
The mean
BMI pre - RYGB was 46.6 + - 5.9 kg / m2 , and the mean % EBWL ( percent excess
body weight lost ) of the
patients at 12 and 24 months post - revision were 56.2 % and 64.3 % , respectively . -
pubmed
Effects on
cancer patients of leukapheresis with the continuous - flow blood cell separator . -
pubmed
The immunologic effects of leukapheresis on
cancer patients and three other groups of donors using the continuous - flow blood cell separator are presented according to the protocol described in the preceding article . -
pubmed
Transient declines were noted in per cent T - lymphocytes of some , but not all , leukapheresed normal donors and
cancer patients . -
pubmed
There were no changes in lymphocyte - mediated
cytotoxicity to a
melanoma cell line in 2 of 4
melanoma patients , while values in 2
patients fell by about one - half within 4 hours and returned to preleukapheresis levels by 24 hours . -
pubmed
Oestrogen treatment of
male rats causes "
feminization " of the hepatic
androstenedione metabolism . -
pubmed
The
patient had
lymphangioma of the orbit which evidently had bled secondary to increased venous pressure and injection of contrast bolus . -
pubmed
Both of the 2
patients with transient
visual disturbances had
diabetic retinopathy . -
pubmed
A large number of
oxanilic acid esters and
N - heteroaryl oxamic acid esters were prepared and found to have antiallergic activity using the
rat passive cutaneous
anaphylaxis ( PCA ) test . -
pubmed
Prevalence of
dental caries and
enamel defects in the primary dentition of Antiguan pre - school
children aged 3 - 4 years including an assessment of their habits . -
pubmed
The
sulfate concentration determined by the proposed method in
human blood serum ( n = 6 in each instance ) was 35.4 - 43.3 micrograms ml-1 in normal
persons , 50.3 - 62.5 micrograms ml-1 in
jaundice patients and 83.3 - 155.6 micrograms ml-1 in
diabetic patients . -
pubmed
An important question is how to use such substances in an effective , directed way to reduce
cancer risk in
humans . -
pubmed
However , CO2ER in experimental
animals tended to decrease 12 hours after
brain injury and was not significantly different from that in controls . -
pubmed
Evaluation of
Mycobacterium leprae particle agglutination test , using eluates of filter paper blood
spots . -
pubmed
Attention is drawn to the existence of this rare form of
aphasia and to the lack of appropriate educational facilities for aphasic
children in general . -
pubmed
Fistulotomy , coupled with insertion of stents , was successful in seven of eight
patients and was associated with relief of
jaundice . -
pubmed
Thirty - one
patients with advanced
carcinoma of the pancreas and with no prior exposure to chemotherapy were treated with
HCFU . -
pubmed
Hepatobiliary injury associated with experimental small - bowel bacterial overgrowth in
rats . -
pubmed
[ Anisotropy and reentrant
ventricular tachycardia : experimental model in the isolated
rabbit heart ] . -
pubmed
The purpose of this study was to study the role of anisotropic distribution of conduction velocity in the initiation and perpetuation of
ventricular tachycardia in an experimental model of sustained reentrant
ventricular tachycardia in the Langendorff perfused
rabbit heart . -
pubmed
Metabolic changes in
man under
hypokinesia and physical exercise . -
pubmed
It was theorized that physical exercise may be used to prevent the development of metabolic changes in
man under
hypokinesia (
diminished muscular activity ) . -
pubmed
In this investigation we assessed the efficacy of physical exercise in attenuating
metabolic disturbances in twelve physically healthy
men aged 19 to 23 years under 100 days of
hypokinesia and 15 days of a readaptation period . -
pubmed
It was concluded that
hypokinesia caused marked debilitating metabolic changes in
man . -
pubmed
We measured local cerebral metabolic rate for
glucose ( ICMRGIc ) using positron emission tomography ( PET ) in six
children with
Sturge - Weber syndrome (
SWS ) and in six neurologically asymptomatic
children with
facial capillary hemangioma suggestive of
SWS . -
pubmed
Children with advanced
SWS showed markedly depressed ICMRGIc in the anatomically affected cerebral hemisphere in a distribution that extended beyond the abnormalities depicted on computed tomography scan . -
pubmed
In two
infants with
SWS and recent
seizure onset , interictal PET revealed a paradoxical pattern of increased ICMRGIc in the cerebral cortex of the anatomically affected hemisphere . -
pubmed
Subsequent PET ( 28 months later ) in this
child revealed the typical ICMRGIc pattern seen in advanced
SWS . -
pubmed
In neurologically asymptomatic
children with the facial stigmata of
SWS and in
children with early
SWS , PET provides a sensitive measure of the extent and degree of
cerebral metabolic impairment . -
pubmed
Serial PET studies in
children with
SWS can be used to assess
disease progression and , together with computed tomography or magnetic resonance imaging , may be useful in the selection of suitable candidates for cerebral hemispherectomy or focal cortical resection . -
pubmed
We report data on 43
patients with
polyarteritis affecting the kidneys . -
pubmed
The majority ( 41
patients ) had renal histological evidence of microscopic
polyarteritis . -
pubmed
These results suggest that our approach to treatment should be modified towards lessening immunosuppression in older
patients and in
patients with
renal failure at diagnosis . -
pubmed
Forearm and finger hemodynamics , blood pressure control , and lipid changes in
diabetic hypertensive patients treated with
atenolol and
prazosin . -
pubmed
Antihypertensive medications that reduce blood pressure and improve peripheral perfusion would have advantages in
diabetic hypertensive patients . -
pubmed
In a randomized , two - placebo - period , single - blind , two - way , crossover study , finger and forearm blood flow , lipid levels , and blood pressure control were determined in 19
diabetic hypertensive patients given
prazosin and
atenolol , with each drug and placebo period lasting four weeks . -
pubmed
In conclusion ,
prazosin demonstrated a potentially more appropriate hemodynamic profile than
atenolol in
diabetic hypertensive patients in this study . -
pubmed
Only a few
yeast strains did not display any killer activity against the aerobic actinomycetes studied , thus confirming that the killer phenomenon is widespread among microorganisms . -
pubmed
We report the details of a young
woman in whom
pericardial tamponade developed acutely following preparation for allogeneic bone marrow transplantation for
acute lymphoblastic leukaemia . -
pubmed
The application of digital coronary arteriography in the evaluation of
patients with known or suspected
coronary artery disease is considered . -
pubmed
The use of an intraoral mental nerve block greatly decreases the
pain for the
patient . -
pubmed
A rapid automatic method for determining
shock sensitivities of
mice . -
pubmed
Strains of
Streptomyces tenebrarius and biosynthesis of
nebramycin . -
pubmed
The surgical specimens from three resected
giant - cell carcinomas are described and the subsequent courses of the
patients are summarized . -
pubmed
Despite the aggressive behaviour of this type of
cancer ,
patients may survive for many years if the
tumour is resected . -
pubmed
The interaction of
metoclopramide and two dopaminergic agonists ,
dopamine and
apomorphine , was investigated on ganglionic transmission at the superior cervical
ganglion of the anaesthetized
cat . -
pubmed
An abnormal
tryptophan metabolism is present in
patients affected by
Erithematodes with high excretion particularly of
kynurenines and
xanthurenic acid . -
pubmed
Both
patients initially developed clinical symptoms of
multiple sclerosis :
visual disturbances , intention
tremor ,
reduced abdominal reflexes ,
impaired coordination and difficulties with walking . -
pubmed
After the exposure to
methanol had ceased the
multiple sclerosis symptoms persisted in
patient 1 but disappeared gradually in
patient 2 (
patient 2 had a history of
excessive alcohol consumption , which is a critical fact in this discussion ) . -
pubmed
Ultimately autopsies confirmed this picture : histological examination of
patient 1 revealed plaques in the spinal cord , in the stem and in the proximity of the lower horn of one lateral ventricle , whereas no localized
demyelination could be found in patient 2 . -
pubmed
An acute
interstitial nephritis was found in a
patient with
sudden renal failure and
lung infection caused by Legionella
pneumophilia . -
pubmed
Quantitative changes in the state of the nucleolar apparatus of endothelial cells in the
rabbit jugular veins were studied at regeneration after
trauma produced either at 8 - 10 a.m. or at 8 - 10 p.m. -
pubmed
Green turtle fibropapillomatosis : challenges to assessing the role of environmental cofactors . -
pubmed
Green turtle fibropapillomatosis (
GTFP ) is a growing threat to the survival of
green turtle (
Chelonia mydas ) populations worldwide . -
pubmed
HF neck suction induced a 0.20 - Hz component in all 16 control subjects and none of the 26 transplant
subjects . -
pubmed
Intravenous cholangiography detected
common bile duct ( CBD ) stones in 10
patients , of whom only five had a dilated
CBD ( & gt ; 8 mm ) . -
pubmed
Tritrichomonas foetus is a protozoan parasite associated with
reproductive failure in the
bovine . -
pubmed
As a result there have been only two cases of
bovine trichomoniasis in the UK over the past 20 years . -
pubmed
METHODS :
Wistar rats were sensitised with a suspension of heat killed
Mycobacterium tuberculosis in oil in the scruff of the neck and challenged intra - articularly with stress protein or M
tuberculosis preparations . -
pubmed
Gossypol inhibits basal and
estrogen - stimulated DNA synthesis in
human breast carcinoma cells . -
pubmed
Estrogen stimulates the growth of hormone - dependent
human breast cancer . -
pubmed
GP at 10.0 and 20.0 microM inhibited both basal and E2 - stimulated DNA synthesis in
human breast cancer cells . -
pubmed
Prevalence of
aortic valve stenosis in
patients affected by
gastrointestinal angiodysplasia . -
pubmed
The aim of this study was to examine the prevalence of
aortic valve stenosis in
patients with
gastrointestinal angiodysplasia . -
pubmed
METHODS : We studied retrospectively 83
patients submitted to gastrointestinal endoscopy and found affected by
angiodysplasia . -
pubmed
Although no murmurs were present in 15
patients ( 25 % ) , some echocardiographic abnormalities such as
aortic leaflet sclerosis ,
mitral annular calcification , their association , or trivial
mitral regurgitation detectable only at PW - Doppler were found . -
pubmed
Abnormal hemostatic profiles indicating
hemorrhagic tendency have been reported in
rodents exposed to prolonged fluctuation in ambient temperature , known as SART ( specific alternation of rhythm in temperature)-stressed animals . -
pubmed
We observed large peripheral
tears of the retinal pigment epithelium in two
patients , a 59 - year - old
man and a 15 - year - old
girl , who had acute
retinal necrosis . -
pubmed
Both
patients had curled folds of tissue at the posterior edge of the
retinal pigment epithelial tear . -
pubmed
Effective chemotherapy of
tuberculosis requires rapid assessment of drug sensitivity because of the emergence of multidrug - resistant
Mycobacterium tuberculosis . -
pubmed
Signals could be detected within minutes after
infection of virulent
M. - pubmed
[ Arterial
hypertension in
patients with
terminal kidney failure : pathogenetic variants and treatment principles ] . -
pubmed
We isolated one clone from a
human genomic phage library , which represents a partial
ALD pseudogene , spanning exon 7 to exon 10 and exhibits approximately 93 % sequence homology with the
ALD gene in this region . -
pubmed
Lumbar , brain - stem , and cortical PTN SEPs were intraoperatively monitored in 7
patients undergoing repair of
aortic coarctation under variable
isoflurane concentration ( up to 1.2 % ) . -
pubmed
PURPOSE : A 63 - year - old
female with
Fuchs ' endothelial corneal dystrophy ,
stromal edema and
subepithelial scarring was inappropriately treated with phototherapeutic keratectomy , leading to a central focal circular
corneal scar and
decreased visual acuity that required penetrating keratoplasty . -
pubmed
METHODS : From 1990 - 1995 , during the five year period , 44 ( 35.2 % ) of 125
patients with
sarcoidosis at LAC + USC Medical Center had liver involvement . -
pubmed
The outcome of
patients who receive treatment remains similar , as far as liver function is concerned , suggesting that most of the
patients with
liver involvement undergo natural remission . -
pubmed
Unless the
patient has progressive
liver dysfunction , it is advisable to monitor liver enzymes periodically and obtain liver biopsies only if clinically indicated . -
pubmed
These include legal regulations , international guidelines for evaluating antiparasitic drugs , the refinement of animal models for
parasitic infections , cryopreservation and cultivation of parasites in vitro or in
chicken eggs , the maintenance of arthropods by artificial feeding , and the use of immunological and molecular in vitro techniques ( e.g. -
pubmed
Efficacy and safety of
loratadine plus
pseudoephedrine in
patients with
seasonal allergic rhinitis and mild
asthma . -
pubmed
Although
nasal obstruction may play an important role in modulating lower airway function , no prior trial has used a decongestant in combination with an antihistamine in
patients with
allergic rhinitis and concomitant
asthma . -
pubmed
OBJECTIVE : We sought to determine the efficacy and safety of
loratadine ( 5 mg ) plus
pseudoephedrine ( 120 mg ) ( L / P ) twice daily in
patients with
seasonal allergic rhinitis and mild
asthma . -
pubmed
METHODS : We conducted a randomized , double - blind , placebo - controlled trial of L / P in 193
subjects during the
fall allergy season . -
pubmed
RESULTS : Total
rhinitis and
asthma symptom severity scores were significantly reduced in
patients receiving active therapy compared with those receiving placebo throughout the 6 - week study . -
pubmed
These results were confirmed by comparing expression levels between
normal and
neoplastic human prostate tissues using Northern analysis . -
pubmed
[ Intermittent
antero - medial divisional block in
patients with
coronary disease ] . -
pubmed
Intravenous infusion of
PCA50941 ( 100 microg / min ) reversed the hemodynamic variables from the
shock state to control values within 20 min in 5 of 6
animals , whereas i.v . -
pubmed
administration of
Bay K 8644 ( 10 - 30 microg / min ) was not effective in 4 of 5
animals , and the vehicle (
DMSO ) was not effective in none of 4
animals in reversing the hemodynamic
shock state . -
pubmed
Ammonium tetrathiomolybdate (
TTM ) is the treatment of choice for chronic
Cu poisoning in
sheep and is recommended in
Wilson ' s disease . -
pubmed
UNLABELLED : We evaluated the effect on the diagnostic yield of visceral arteriography in
patients with acute
gastrointestinal bleeding of a protocol requiring a positive
99mTc - red blood cell scintiscan before the performance of arteriography ( scintigraphic screening ) . -
pubmed
CONCLUSION : Scintigraphic screening appears to increase by a factor of 2.4 the diagnostic yield of arteriography by screening out
patients who are not actively
bleeding at the time of the examination , thus sparing them the risks and costs of a nondiagnostic invasive study . -
pubmed
The
yeast strain complemented by At . -
pubmed
OBJECTIVE : To assess in
children with a transcranial Doppler the effect on cerebral blood flow velocities of
desflurane , whose cerebral vasodilator effects have been studied in animals and in
adults with
intracranial lesions . -
pubmed
In
patients with
diabetes mellitus optimal regulation of the blood
glucose levels , with a view to preventing
glycosuria , is a condition of speedy recovery . -
pubmed
Successful triple - antibiotic therapy for
cutaneous infection due to
Mycobacterium chelonae . -
pubmed
The
patient was free of
recurrence 3 years after follow up . -
pubmed
PURPOSE : Gene modified autologous
tumor cell vaccines have demonstrated a protective and therapeutic effect in
murine tumor model systems . -
pubmed
MATERIALS AND METHODS : We obtained 1 cm3
tumor tissue from 12
patients undergoing resection of primary or metastatic
renal cell carcinoma . -
pubmed
A retrospective evaluation of the relationship between serum bactericidal and inhibitory titres and treatment outcome in 195 adult Thai
patients with severe
melioidosis was conducted . -
pubmed
This literature review demonstrates that hospitalised
patients may not be receiving adequate
pain relief due to health professionals ' belief that optimum doses of analgesia may affect patients ' respiratory capability . -
pubmed
We have studied in vitro and in vivo activity of
cyclosporin - A (
CSA ) on hematopoiesis in
patients affected by
hypoplastic MDS without blast excess . -
pubmed
DESIGN AND METHODS : Nine consecutive
patients with
hypoplastic refractory anemia (
RA ) , followed up in our out -
patient unit , were treated with
CSA at daily doses of 1 - 3 mg / kg for at least three months . -
pubmed
INTERPRETATION AND CONCLUSIONS : About one half of hypoplastic
RA patients benefited from
CSA treatment . -
pubmed
Similar additive effects may be unexpectedly efficient and beneficial in
humans after
infections with persistent viruses such as
hepatitis C virus and
hepatitis B virus and possibly
human immunodeficiency virus . -
pubmed
It is possible that concurrent prescription of cytozar together with magnetization of blood in
patients with
hemoblastoses should permit enhancing the efficacy of treatment . -
pubmed
Employment of weak magnetic fields is a satisfactory and worth - while therapeutic attempt to be made in a multimodality treatment of
patients with
hemoblastoses . -
pubmed
Although the molecular mechanisms whereby this hormone modulates the sex ratio of
malaria parasites remain to be elucidated , it probably activates , within the
parasite , transduction pathways similar to those found in other eukaryotes . -
pubmed
An
osteochondral defect was created with a 5 - mm circular punch in the humeral articular surface of both glenohumeral joints of 32 adult
White Leghorn chickens . -
pubmed
Patients undergoing SATE for
LGIB were clinically monitored for development of
ischemic complications . -
pubmed
Of 523 admissions for
UGIB and
LGIB , 35
patients ( 6.7 % ) underwent SATE as definitive therapy for control of
gastrointestinal hemorrhage ( 25
UGIB and 10
LGIB ) . -
pubmed
Initial control of
bleeding was achieved in 23/25
UGIB and 10/10
LGIB patients . -
pubmed
Rebleeding at less than 30 days occurred in 5/23
UGIB and 2/10
LGIB patients . -
pubmed
SATE is an excellent therapeutic method for
GI bleeding in selected
patients , and definitive control is frequently afforded . -
pubmed
However , by bypassing a urological evaluation the
man might not learn the cause of
infertility and not be offered specific corrective therapy . -
pubmed
Of the remaining 6
patients 1 had
testis cancer , 1
prostate cancer , 3
diabetes mellitus and 1
hypothyroidism . -
pubmed
These transfectants were then analyzed for differences in
metastasis formation in
athymic mice . -
pubmed
An 11 - year - old boy presented with
fever ,
vomiting ,
rash ,
limping and
blisters on his feet after a finger
bite by his domestic
rat . -
pubmed
MATERIALS AND METHODS : The medical records of 22
patients with
ATB were reviewed . -
pubmed
RESULTS : Ten
patients had biopsy - proven
ATB , 11 had extra - abdominal
TB with clinical suspicion of
ATB and 1 had a positive trial of therapy . -
pubmed
Vertebral compression and
eosinophilia in a
child with
acute lymphatic leukemia . -
pubmed
CONCLUSION : In
patients with
atopic asthma , changes in bronchial eosinophils and lung function during
steroid therapy are closely related but do not occur simultaneously . -
pubmed
Symptomatic
diabetic and non - diabetic neuropathies in a series of 100
diabetic patients . -
pubmed
We have reviewed the clinical and pathological data of a series of 100 consecutive
diabetic patients with symptomatic
neuropathy in order to learn more about the causes of
neuropathy in this population and on the
signs and symptoms that could suggest another cause than
diabetes in this setting . -
pubmed
Diabetes accounted for 74 % of the
neuropathies in the whole group of
patients and for 79 % of those with a fiber length dependent pattern of
neuropathy . -
pubmed
One third of
patients had a
neuropathy unrelated to
diabetes . -
pubmed
As a group , 71 % of the
patients presented either a length dependent
diabetic polyneuropathy (
LDDP ) or a proximal
diabetic neuropathy (
PDN ) . -
pubmed
Conversely , most
patients with proximal
diabetic neuropathy had usual features . -
pubmed
Chronic inflammatory demyelinating neuropathy that was diagnosed in 9 % of the
patients was the most common non - diabetic cause of
neuropathy in this population . -
pubmed
PURPOSE :
Patients who have extensive
stricture disease , those in whom
hypospadias repair fails and those who sustain significant
urethral trauma pose a reconstructive challenge for genitourinary surgeons . -
pubmed
Unfortunately , one - third of patients have metastatic
disease at the time of diagnosis and approximately 50 % of the
patients undergoing surgical resection for less advanced disease eventually relapse . -
pubmed
A combined impact of
spinal deformity and impaired blood flow in the segmental arteries at the level of lesion on the severity of
neurological disorders and on deterioration of life quality in
patients with
spinal inflammatory diseases has been found . -
pubmed
Nosocomial infections among
HIV - positive and
HIV - negative patients in a Brazilian
infectious diseases unit . -
pubmed
This study compared the incidence of
NI among
HIV - positive and
HIV - negative inpatients . -
pubmed
METHODS : Patients from an
infectious diseases ward who were classified as positive and negative regarding their
HIV status were followed - up for 21 months in a prospective cohort study . -
pubmed
Overall , HIV - positive patients were more likely to have a
BSI than were
HIV - negative patients ( P = .005 ) . -
pubmed
CONCLUSIONS : In this study the
HIV - positive patients were more likely to have
NI than were the
HIV - negative patients . -
pubmed
Overall , HIV - positive patients are at increased risk for an
NI caused either by
S aureus or a
BSI . -
pubmed
The authors studied homeostasis in 182
patients , including 126
patients with exudative
pleuritis of tuberculous etiology and 56 with
parapneumonic pleuritis . -
pubmed
Impaired responsiveness in
patients with
exudative pleuritis substantially affected the efficiency of etiotropic treatment . -
pubmed
At the end of the basic course of therapy , the rate of marked residual pleural changes was 84.6 % in
patients with
tuberculous pleuritis ( Subgroup 1 ) . -
pubmed
Greenberg ( Greenberg 1997 ) observed that a single session of right prefrontal cortex stimulation produced a significant decrease in compulsive urges in
OCD patients lasting over eight hours . -
pubmed
[ Does
cortisone influence experimental
cutaneous tuberculosis in the
rat ] . -
pubmed
Bilateral ablation of dorsolateral frontal cortex in the newborn
animal failed to produce the
frontal lobe syndrome typical of the adolescent and adult stages . -
pubmed
At this time , no significant differences between normal
animals and
animals with
prefrontal lesions were found . -
pubmed
[ Is there another toxin produced by the disintegration of dead tissues in cases of
gas gangrene caused by
W. - pubmed
DIAGNOSIS OF
CORNEAL DISEASE IN
CHILDREN . -
pubmed
Influence of
warm ischemia injury on hepatic functional status and survival of liver graft in
rats . -
pubmed
OBJECTIVE : To investigate the changing patterns of functional and histological status , observe the posttransplantation survival of liver graft under different warm
ischemia time ( WIT ) in
rats , and determine the maximum limitation of liver graft to warm
ischemia . -
pubmed
CONCLUSIONS : These results indicate that
rat liver graft could be safely subject to warm
ischemia within 30 minutes . -
pubmed
OBJECTIVE : We sought to determine whether reducing treatment frequency and UVA dose affects the therapeutic efficacy of oral PUVA for
patients with
chronic plaque psoriasis . -
pubmed
According to our experience of over 100 hindlimb transplantations , in
rats , catching the posterior wall with an anterior wall suture is the most common cause of
thrombosis and acute transplant failure . -
pubmed
RESULTS : Transplanted
human peripheral lymphocytes survived and expressed EGFP in the
mice over the 6- to 8 - week posttransplant period without any signs of
graft - vs - host disease . -
pubmed
MATERIALS AND METHODS : Orthotopic
PC3 prostate tumours were established in male
severe combined - immunodeficient mice ; on day 3 the
mice were randomly assigned to one of four groups :
paclitaxel 10 mg / kg intraperitoneally once a week ;
STI571 50 mg / kg once a day for 6/7 weekdays ; combined
paclitaxel and
STI571 ; and vehicle - treated controls . -
pubmed
METHOD : Forty - six
tuberculosis patients were enrolled in the study . -
pubmed
RESULTS :
Atrial fibrillations occurred in 43,674 ( 14.9 % )
DM patients vs. 57,077 ( 10.3 % ) in the control group ( p<0.0001 ) . -
pubmed
Spinal cord stimulation for critical leg
ischemia : a review of effectiveness and optimal
patient selection . -
pubmed
Patients suffering from inoperable
critical leg ischemia (
CLI ) ultimately face a major amputation . -
pubmed
Subjecting these
ZAG deficient animals to standard or lipid rich food regimens led to increased
body weight in comparison to identically treated wild - type
mice . -
pubmed
A 32 - year - old
woman was treated with long - term
voriconazole therapy for recurrent
aspergillosis associated with chronic
granulomatous disease . -
pubmed
The
photosensitivity reaction resolved after the
patient changed therapy to
posaconazole . -
pubmed
The S - ECC group contained 98
children with more than 5 decayed teeth , and the control group contained 94
caries - free
children . -
pubmed
DESIGN AND METHODS : In the present retrospective analysis ,
patients with high - grade
non - Hodgkin ' s lymphoma with past history of
tuberculosis and have had adequate antitubercular therapy were identified from a
Lymphoma Group study . -
pubmed
RESULTS : A cohort of eight
patients with past history of
tuberculosis was selected from 141
patients of high - grade
non - Hodgkin ' s lymphoma . -
pubmed
None of these
patients developed reactivation of
tuberculosis . -
pubmed
Invasive
pneumococcal disease in older children and adults declined markedly after introduction in 2000 of the
pneumococcal conjugate vaccine for young children . -
pubmed
Prehospital analgesia with acupressure at the Baihui and Hegu points in
patients with
radial fractures : a prospective , randomized , double - blind trial . -
pubmed
As acupressure has been deemed effective for
pain management by the National Institutes of Health , we conducted a study to evaluate its effectiveness in prehospital
patients with isolated distal radial
fracture . -
pubmed
At the hospital ,
patients in the true - points group had significantly lower
pain ( 36.6 + /- 11.0 vs 56.0 + /- 13.3 VAS score , P & lt ; .001 ) and
anxiety scores ( 34.9 + /- 22.2 vs 53.4 + /- 19.7 VAS score , P = .022 ) . -
pubmed
CONCLUSION : Acupressure in the prehospital setting effectively reduces
pain and
anxiety in
patients with
distal radial trauma . -
pubmed
CASE PRESENTATION : We present a case of a young
male who was transferred to our hospital because of
shock and
multiple organ failure after a complicated pericardial biopsy . -
pubmed
During emergency surgery that followed , the
patient died because of uncontrolled
hemorrhage . -
pubmed
CONCLUSION : This case highlights the difficulties both in early diagnosis and in the management of
patients with
cardiac angiosarcoma . -
pubmed
In a previous study , it was demonstrated in
human neuroblastoma SH - SY5Y cells that enhanced oxidative stress was related to
METH - induced apoptosis . -
pubmed
To determine if loss of cytoskeletal tension following stress deprivation decreases the mechanoresponsiveness of tendon cells , we cultured
rat tail tendons under stress - deprived conditions for 48 hours and then cyclically loaded them for 24 hours at 1 % , 3 % , or 6 %
strain at 0.17 Hz . -
pubmed
Contrast - enhanced CT evaluation of clinically and mammographically occult multiple
breast tumors in
women with unilateral early
breast cancer . -
pubmed
If the aetiology of
trigeminal neuralgia (
TN ) and other typical
neuralgias must be brought back to the
peripheral injury , their pathogenesis could involve central allodynic mechanisms , which , in
patients with inter - critical
pain , also engage the nociceptive neurons at the thalamic - cortical level . -
pubmed
Sarcoptic mange in wild
raccoon dogs (
Nyctereutes procyonoides ) in Korea . -
pubmed
Purification and characterization of a new platelet aggregation inhibitor with dissociative effect on
ADP - induced
platelet aggregation , from the venom of
Protobothrops elegans (
Sakishima - habu ) . -
pubmed
METHODS : Eighteen SNPs in three genes , representing optimal haplotype - tagging sets , were genotyped in 355
COPD patients and 195 healthy smokers . -
pubmed
We performed a retrospective study of all
patients admitted to a Level 1
trauma center with isolated
gunshot injury to the head during 6 1/2 years . -
pubmed
Seventy - two
patients with isolated
gunshot wounds to the head were admitted . -
pubmed
Recently , our group has evaluated the effect of various HN - derivatives on the
3 - quinuclidinyl benzilate (
QNB)-induced
impairment of spatial orientation and memory in
rats , by employing the T - maze test . -
pubmed
This study examined general deficits in positive stimuli evaluation in
adults with
Attention Deficit Hyperactivity Disorder (
ADHD ) . -
pubmed
We investigated the event - related potentials to positive , negative and neutral pictures in 32
adults with
ADHD and 32 control subjects . -
pubmed
We found significantly reduced EPN values for the
ADHD patients compared to the healthy controls , but only in the positive stimuli condition , without any significant differences in the negative stimuli condition . -
pubmed
MATERIALS AND METHODS : Seventeen
women ( mean age 48.5 years ) with
uterine cervical cancer received conventional magnetic resonance imaging ( MRI ) and DWI prior to chemoradiation and after 1 and 2 months of therapy . -
pubmed
Water and solute transport through different types of pores in peritoneal membrane in
CAPD patients with ultrafiltration failure . -
pubmed
Disease - modifying therapy is ineffective in disabled
patients ( Expanded Disability Status Scale [ EDSS ] & gt ; 6.5 ) with secondary progressive
multiple sclerosis (
MS ) without
relapses , or in primary progressive
MS . -
pubmed
To observe use of disease - modifying therapies in
patients with
progressive multiple sclerosis and EDSS & gt ; 6.5 . -
pubmed
The plant extract
Isatis tinctoria L. extract ( ITE ) inhibits allergen - induced
airway inflammation and hyperreactivity in
mice . -
pubmed
Antioxidant nutrient intakes and corresponding biomarkers associated with the risk of
atopic dermatitis in young
children . -
pubmed
BACKGROUND / OBJECTIVES : To investigate the association of antioxidant nutritional status with the risk of
atopic dermatitis (
AD ) in young
children in a case - control , population - based study . -
pubmed
Final analysis included 180
AD ( mean age 5.3+/-0.9 years ) and 242 non -
AD ( mean age 5.2+/-1.0 years )
children . -
pubmed
Human conventional
renal cell carcinoma (
CRCC ) remains resistant to therapy . -
pubmed
Introduction of portable computed tomography scanners , in the treatment of
acute stroke patients via telemedicine in remote communities . -
pubmed
BACKGROUND : Thrombolysis is an established treatment in selected
patients who present early to hospital after symptoms of
acute ischaemic stroke . -
pubmed
Treatment can only be offered after the
patient has been assessed by highly trained physicians and imaging studies have ruled out a
brain haemorrhage . -
pubmed
METHODS : We report our preliminary experience with the portable computed tomography scanner in a remote community where Telemedicine was successfully used to evaluate and treat
patients presenting with symptoms suggestive of an
acute ischaemic stroke . -
pubmed
All
patients were evaluated remotely by a
stroke neurologist in a TeleStroke service situated 207 km from the rural site . -
pubmed
In three
patients , thrombolysis was not offered because the computed tomography showed evidence of
brain haemorrhage : two
intracerebral haemorrhage and one
subarachnoid haemorrhage . -
pubmed
Repeat computed tomography scans showed a small
haemorrhagic transformation in one
patient . -
pubmed
New imaging technologies have advanced our ability to treat
lung cancers through enhanced and extended visualization of the
tumor as well as
patient and treatment response . -
pubmed
Anti - oxidative effects of
d - allose , a rare
sugar , on
ischemia - reperfusion damage following focal
cerebral ischemia in
rat . -
pubmed
Rats were subjected to transient
middle cerebral artery occlusion (
MCAO ) for 1 h under
pentobarbital anesthesia . -
pubmed
In another set of
rats , apurnic / apyrimidic abasic sites ( AP - sites ) and
8 - hydroxy-2 '- deoxyguanosine (
8 - OHdG ) , oxidative stress markers , were investigated 24 h after
MCAO to examine the anti - oxidative effects of
D - allose . -
pubmed
The majority of
prostanoid DP receptor - expressing cells in both
rat and
human asthmatic lungs are infiltrative macrophages and/or monocytes . -
pubmed
Remission of
endometriosis by hyperbaric
oxygen treatment in
rats . -
pubmed
We designed this prospective , randomized controlled animal study to determine the effects of hyperbaric
oxygen (
HBO ) on experimentally induced
endometriosis in a
rat model . -
pubmed
Surgical induction of
endometriosis was performed in 40 , nonpregnant , female ,
Wistar - Albino rats at the Experimental Medicine Research Center of Istanbul University ( DETAE ) . -
pubmed
Hyperbaric
oxygen treatment for 2 hours a day for 6 weeks resulted in significant remission of
endometriosis in
rats . -
pubmed
Moreover , as several of the genes we studied have been linked to
human gliomas , our results suggest that this linkage could reflect their organization into a conserved pathway for the control of glial cell proliferation . -
pubmed
Peginterferon alpha and
ribavirin combination therapy in
patients with
hepatitis C virus - related liver cirrhosis . -
pubmed
BACKGROUND / AIMS :
Pegylated interferon (
peginterferon ) and
ribavirin combination therapy is less effective and associated with a higher frequency of serious complications in
chronic hepatitis C patients with
cirrhosis than in noncirrhotic patients . -
pubmed
This study evaluated the efficacy and tolerability of
peginterferon and
ribavirin treatment in
patients with
hepatitis C virus (
HCV)-related
cirrhosis . -
pubmed
METHODS : Eighty - six
patients with clinically diagnosed
liver cirrhosis were treated with either
peginterferon alpha-2a ( n=51 ) or
peginterferon alpha-2b ( n=35 ) plus
ribavirin . -
pubmed
RESULTS : Of the 86
patients ( 55
males ) , 48
patients ( 55.8 % ) had
HCV genotype 1 infection and 38 ( 44.2 % ) had genotype non-1
infection . -
pubmed
CONCLUSIONS :
Peginterferon and
ribavirin combination therapy was relatively effective and feasible for clinically diagnosed
HCV patients , especially in those with genotype non-1
infection and low baseline viral load . -
pubmed
Exercise training attenuates acute
hyperalgesia in
streptozotocin - induced
diabetic female
rats . -
pubmed
OBJECTIVES : We investigated the effects of chronic ( eight weeks ) low - to moderate - intensity swimming training on thermal
pain sensitivity in
streptozotocin - induced
diabetic female
rats . -
pubmed
One day after the last exercise protocol ( 60 min / day , five days / week for eight weeks ) in the trained groups or after
water stress exposure ( ten min / twice a week ) in the sedentary groups , the
rats were subjected to a hot plate test . -
pubmed
RESULTS : After eight weeks of swimming training ,
streptozotocin - induced
diabetic rats presented a significantly lower body mass ( trained : 219.5 + - 29 g , sedentary : 217.8 + - 23 g ) compared with the normoglycemic groups ( trained : 271 + - 24 g , sedentary : 275.7 + - 32 g ) . -
pubmed
CONCLUSION : Low - to - moderate swimming training for a long duration reduces thermal
hyperalgesia during a hot plate test in
streptozotocin - induced
diabetic female
rats . -
pubmed
Polysomnography in combination with a questionnaire ( the Sleep Disturbance Scale for
Children ) was performed in 12 Dutch
patients with
Rett . -
pubmed
In 8
children , central
apneas were present during the day often with obstructive
apneas at night . -
pubmed
Significant respiratory complaints were present in 3
patients , all had
obstructive sleep apnea syndrome . -
pubmed
Of the 12
patients with
Rett , 8 ( 67 % ) snored , and in 5
obstructive sleep apnea syndrome was present . -
pubmed
A novel actinomycete ,
strain A4036(T ) , was isolated from a soil sample collected from the Jabi district in Abuja , Nigeria . -
pubmed
The taxonomic position of
strain A4036(T ) was established using a combination of genotypic and phenotypic analyses . -
pubmed
The type
strain is
A4036(T ) (= DSM 45507(T ) = KCTC 19870(T ) ) . -
pubmed
Disease phenotype in
sheep after
infection with cloned murine
scrapie strains . -
pubmed
Phenotypic characterization of
scrapie strains in
sheep can be attempted by histological , immunohistochemical and biochemical approaches , but it is widely considered that strain confirmation and characterization requires
rodent bioassay . -
pubmed
Examples of
scrapie strains obtained from original
sheep isolates by serial passage in
mice include ME7 , 79A , 22A and 87V. -
pubmed
It is mutated in approximately half of all
human cancers , leading to aberrant cell growth . -
pubmed
Taxol and
taurine protect the renal tissue of
rats after unilateral
ureteral obstruction : a stereological survey . -
pubmed
Compared with the untreated UUO
animals , the volume of
necrotic and fibrotic tissues decreased -53 % and -63 % in the UUO
rats treated with
Taxol and
taurine , respectively ( p<0.01 ) . -
pubmed
Reducing the fasting period reduced the body
weight loss in both species , and
mice on shorter fasts could be group - housed , as hunger - induced fighting was lessened . -
pubmed
BACKGROUND : We have created a theoretical algorithm for
venous thromboembolism prophylaxis after
traumatic brain injury (
TBI ) known as the Parkland Protocol , which stratifies
patients into low- , medium- , and high - risk categories for spontaneous progression of
hemorrhage . -
pubmed
At admission , all
patients were preliminarily categorized per the Parkland Protocol as follows : low risk ( LR ) , patients meeting the modified Berne - Norwood criteria ; moderate risk ( MR ) ,
injuries larger than the modified Berne - Norwood criteria without requiring a neurosurgical procedure ; high risk ( HR ) , any patient with a craniotomy / monitor . -
pubmed
RESULTS : A total of 245
patients with
intracranial hemorrhage were enrolled during the 13 - month study period . -
pubmed
Spontaneous worsening was seen in 7.4 % of LR
patients at 24 hours after
injury , and no LR
patients progressed at 72 hours after
injury . -
pubmed
In
patients initially classified as MR at admission ( n = 42 ) , progression was seen in 42.9 % , with 91.5 % of
patients demonstrating stable computed tomographic head scans at 72 hours after
injury . -
pubmed
In
patients initially classified as HR ( n = 67 ) , 64.2 % demonstrated spontaneous progression of their
TBI patterns , with 10.5 % continuing to progress at 72 hours after
injury . -
pubmed
A comparison of survival and pathologic features of
non - alcoholic steatohepatitis and
hepatitis C virus patients with
hepatocellular carcinoma . -
pubmed
METHODS :
Patients transplanted for
HCV and
NASH at our institution from January 2000 to April 2011 were analyzed . -
pubmed
Patient demographics , disease free survival , explant liver characteristics and
HCC features (
tumour number , cumulative
tumour size , vascular invasion and differentiation ) were compared between
HCV and
NASH liver transplant recipients . -
pubmed
RESULTS : A total of 102 patients with
NASH and 283 patients with
HCV were transplanted . -
pubmed
The incidence of
HCC in
HCV transplant recipients was 22.6 % ( 64/283 ) . -
pubmed
Patients with
NASH -
HCC were statistically older than
HCV -
HCC patients ( P & lt ; 0.001 ) . -
pubmed
A significantly higher proportion of
HCV -
HCC patients had vascular invasion ( 23.4 % vs 6.4 % , P = 0.002 ) and poorly differentiated
HCC ( 4.7 % vs 0 % , P & lt ; 0.001 ) compared to the NASH -
HCC group . -
pubmed
Is cerebral
glucose metabolism affected by chemotherapy in
patients with
Hodgkin ' s lymphoma ? -
pubmed
OBJECTIVE : The aim of the study was to investigate the effect of chemotherapy treatment with
ABVD on brain
glucose metabolism in
patients with
Hodgkin ' s disease (
HD ) . -
pubmed
METHODS : A total of 49
patients ( 23
men , 26
women ; mean age 32 + -9 years ) diagnosed with
HD were included in the study . -
pubmed
CONCLUSION : Our results support the conclusion of a very limited impact of
ABVD chemotherapy on brain metabolism in
patients with
HD . -
pubmed
INTRODUCTION :
Infection is one of the main causes of
patient death and graft failure early after kidney transplantation . -
pubmed
RESULTS : The total number of
infections per
patient per day was not significantly different in peritoneal vs. hemodialysis modality ( 0,029 + /- 0.019 to 0,029 + /- 0,031 , p = ns ) . -
pubmed
PD should be the first choice for renal replacement therapy in
patients with
end stage renal disease . -
pubmed
METHODS : This prospective cohort study included 78 nontreated
patients with
moyamoya disease . -
pubmed
During follow - up periods , de novo silent
microbleeds developed in 4 ( 6.9 % ) of 58 adult
patients . -
pubmed
Hemorrhagic stroke occurred in 4
patients ( 6.9 % ) , all of who had silent
microbleeds on initial examination . -
pubmed
CONCLUSIONS : Careful and long - term follow - up of silent
microbleeds would be essential to improve their outcome in adult
patients with
moyamoya disease . -
pubmed
Practical importance and modern methods of the evaluation of skin microcirculation during chronic
lower limb ischemia in
patients with
peripheral arterial occlusive disease and/or
diabetes . -
pubmed
Skin ischemia is one of the crucial phenomena during chronic
lower limb ischemia in
patients with
peripheral arterial occlusive disease and/or
diabetes . -
pubmed
However , risk stratification for development of
ischemic ulceration and/or
skin necrosis in those
patients is not easy , mostly due to the complex structure of the dermal vascular bed and limited possibilities for studying the skin capillaries in everyday practice . -
pubmed
Myeloid - derived suppressor cells have a central role in attenuated
Listeria monocytogenes - based immunotherapy against metastatic
breast cancer in young and old mice . -
pubmed
BACKGROUND : Myeloid - derived suppressor cells ( MDSCs ) are present in large numbers in blood of
mice and
humans with
cancer , and they strongly inhibit T - cell and natural killer ( NK ) cell responses , at young and old age . -
pubmed
RESULTS : We found that
Listeria(at)-infected MDSC , which delivered
Listeria(at ) predominantly to the microenvironment of
metastases and
primary tumours , where they spread from MDSC into
tumour cells ( infected
tumour cells will ultimately become a target for Listeria - activated immune cells ) . -
pubmed
CONCLUSIONS : Although preclinical studies show that immunotherapy is less effective at old than at young age , our study demonstrates that
Listeria(at)-based immunotherapy can be equally effective against metastatic
breast cancer at both young and old age by targeting MDSC . -
pubmed
METHODS : Nine
patients with focal lesions of the condylar articular cartilage were consecutively treated with arthroscopic PGA -HA - covered
microfracture and bone marrow concentrate ( PGA -HA - CMBMC ) . -
pubmed
In the search for the etiological agent of
Kawasaki disease , we suggest that a
viral infection with potential antigenic similarities to
rabies virus should be entertained . -
pubmed
This study was done to predict the outcome of trial of voiding without catheter ( TWOC ) in
patients with AUR with intravesical prostatic protrusion (
IPP ) detected on transabdominal ultrasound . -
pubmed
METHODS :
Patients with a first episode of AUR secondary to
benign prostatic hypertrophy were assessed with ultrasound following bladder catheterization . -
pubmed
CONCLUSION : Intravesical prostatic protrusion is a useful predictor of success of TWOC in
patients with
AUR . -
pubmed
METHODS :
Patients diagnosed with nonmetastatic T3 + or N1 + esophageal
adenocarcinoma (
ACA ) or
squamous cell carcinoma (
SCC ) from 1995 to 2002 who underwent surgical resection within 6 months of diagnosis were studied . -
pubmed
Mainly induced by the
Enterovirus 71 and
Coxsackievirus A 16 infections , the frequently occurred
HFMD outbreaks have become a serious public health problem in Southeast Asia . -
pubmed
Currently , only a few studies have investigated the
human immunity to
HFMD in China . -
pubmed
The levels of
EV71 and
CA16 specific antibodies before , during and shortly after the 2008 large outbreak of
HFMD were evaluated by the microneutralization test . -
pubmed
Left ventricular diastolic dysfunction is not uncommon in
patients with
chronic renal failure , including those with preserved left ventricular systolic function . -
pubmed
The purpose of this study was to determine the relationship between
left ventricular diastolic dysfunction and incidence of post - operative
pulmonary edema in renal transplantation
recipients with preserved left ventricular systolic function . -
pubmed
METHODS : Pre - operative left ventricular function and incidence of
pulmonary edema were retrospectively studied in 209
patients who underwent living - donor renal transplantation between January 2010 and October 2012 . -
pubmed
In this model ,
mice are fed with the
copper chelator
cuprizone which leads to oligodendrocyte apoptosis and subsequent
microgliosis ,
astrocytosis , and
demyelination . -
pubmed
Expression was analyzed in
tumors from 85
bladder cancer patients and compared to overall survival ( median follow - up of 5.1 years ) . -
pubmed
Years ago , the main
allergy - causing domestic animals were
dogs and
cats , although nowadays there is an increasing number of
allergic diseases related to insects ,
rodents ,
amphibians ,
fish , and birds , among others . -
pubmed
The main
allergic symptoms related to exotic pets are the same as those described for
dog and
cat allergy :
respiratory symptoms . -
pubmed
Tumor specimens were collected from 33 consecutive
patients . -
pubmed
[ On the problem of the evaluation of conditioned reflex formation by means of an electroencephalographic method in
children with
epileptiform syndrome ] . -
pubmed
MATERIALS AND METHODS :
Wistar rats underwent 180 minutes of bilateral lower limb
ischemia and 240 minutes of reperfusion . -
pubmed
Neuroimaging has played a critical role in the management of
patients with
neurological disease , since the first ventriculogram was performed in 1918 by Walter Dandy ( Mezger et al . -
pubmed
Over the last century , technology has evolved significantly , and within the last decade , the role of imaging in the management of
patients with
neuro - oncologic disease has shifted from a tool for gross identification of intracranial pathology , to an integral part of real - time neurological surgery . -
pubmed
Current neurological imaging provides detailed information about anatomical structure , neurological function , and metabolic and metabolism - important characteristics that help clinicians and surgeons non - invasively manage
patients with
brain tumors . -
pubmed
It is valuable to review the evolution of neurological imaging over the past several decades , focusing on its role in the management of
patients with
intracranial tumors . -
pubmed
We thus suggest mechanisms that might ultimately allow for evidence based integration of imaging in the management of
patients with
neuro - oncologic disease . -
pubmed
METHODS : We reviewed medical records of
MESCC patients in our institute who had at least one progressive neurological symptom (
weakness , sensory changes ,
urinary retention , or
nerve root pain ) , were diagnosed by magnetic resonance imaging ( MRI ) , and were treated with at least radiotherapy . -
pubmed
CONCLUSIONS : Our findings suggest that normal walking status at the first physician visit and inclusion of weekends during the pretreatment periods were factors that resulted in treatment delays even for
MESCC patients with emergency
neurological symptoms . -
pubmed
[ Moving activity and wakefulness - sleep cycle changes in a
mouse MPTP model of
Parkinson ' s disease ] . -
pubmed
Finally ,
2 '- HCA potently suppressed the growth of
mouse xenografts representing
human leukemia or
skin cancer . -
pubmed
The
HBV genotypes / subgenotypes , serotypes ,
mixed infections , and S gene mutations of 172 Cuban HBsAg and
HBV - DNA positive patients were determined by direct sequencing and phylogenetic analysis . -
pubmed
This first genetic study of
Cuban HBV viruses revealed only
strains that were interspersed with
strains from particularly Europe , America , and Asia . -
pubmed
Home mechanical ventilation represents a valuable therapeutic option to improve alveolar ventilation in
patients with chronic
respiratory failure . -
pubmed
The prognosis of
patients with local appendiceal
carcinoids is excellent . -
pubmed
The present study reports the case of a 22 - year - old female
patient that presented with recurrent right lower
abdominal pain of a three - year duration . -
pubmed
BACKGROUND : Bronchoscopic lung - volume reduction with the use of one - way endobronchial valves is a potential treatment for
patients with severe
emphysema . -
pubmed
METHODS : We randomly assigned
patients with severe
emphysema and a confirmed absence of collateral ventilation to bronchoscopic endobronchial - valve treatment ( EBV group ) or to continued standard medical care ( control group ) . -
pubmed
The Beneficial Effect of Beta - Blockers in
Patients With
Cirrhosis ,
Portal Hypertension and
Ascites . -
pubmed
BACKGROUND :
Patients with
cirrhosis and portal
hypertensive complications have reduced survival . -
pubmed
As such , it has been suggested that nonselective beta - blocker therapy in
patients with advanced
ascites is harmful . -
pubmed
The aim of this study was , therefore , to determine the risk of mortality in
patients with
cirrhosis and
ascites taking nonselective beta - blocker therapy for the prevention of
variceal hemorrhage . -
pubmed
MATERIALS AND METHODS : This study was a retrospective analysis of 2,419
patients with
cirrhosis and
portal hypertension admitted to Parkland Memorial Hospital ( a university - affiliated county teaching hospital ) from 2003 - 2010 . -
pubmed
Patients were subdivided into those with
varices only ,
ascites only and those with both
varices and
ascites . -
pubmed
Beta - blocker use was also assessed in specific cohorts ; mortality was 21.1 % in
patients with severe
ascites with
varices who were not taking beta - blockers compared with 8.9 % in
patients who were taking beta - blockers ( P = 0.05 ) . -
pubmed
Overall , fewer
patients taking beta - blockers died compared with those not taking beta - blockers in
patients with
varices only ( 6.4 % versus 12.1 % ) and those with
ascites with or without
varices ( 6.6 % versus 18.1 % ) ( P & lt ; 0.001 ) . -
pubmed
CONCLUSIONS : Mortality was lower in
patients with
cirrhosis and
portal hypertension taking nonselective beta - blockers than in those not taking beta - blockers . -
pubmed
The use of nonselective beta - blockers provided a significant survival benefit in
patients with all grades of
ascites , including those with severe
ascites . -
pubmed
This "
primate - specific " pattern may be related to the
human - specific
hearing loss phenotypes of
channelopathy disorders , including the
SLC26A4 - related diseases Pendred syndrome /
DFNB4 . -
pubmed
Time course investigation of
intervertebral disc degeneration in a
rat - tail puncture model . -
pubmed
SIGNIFICANCE : The degenerative changes observed in this
rat - tail puncture model are similar to
human disc degeneration and that this model may be valuable for elucidating the molecular mechanisms and pathways underlying
disc degeneration . -
pubmed
CONCLUSION : This prospective , multi - institutional registry will provide novel oncological and QoL outcomes on
patients with
sinonasal malignancy to inform management decisions and disease prognostication . -
pubmed
Cerebral oximetry as a biomarker of
postoperative delirium in cardiac surgery
patients . -
pubmed
MATERIALS AND METHODS : An observational study was conducted with 30 consecutive
adults with
delirium after cardiac surgery . -
pubmed
RESULTS : All
patients presented
delirium at entry . -
pubmed
The mean oximetry value decreased from 66.4 + -6.7 ( mean+-SD ) to 50.8 + -6.8 on the first day after
delirium onset and increased in
patients whose
delirium resorbed over the 3 days . -
pubmed
Clinicopathological features of histological transformation from extranodal marginal zone
B - cell lymphoma of mucosa - associated lymphoid tissue to
diffuse large B - cell lymphoma : an analysis of 467
patients . -
pubmed
This study analysed incidence ,
patient outcome , immunophenotype and prognostic factors of histological transformation (
HT ) from extranodal marginal zone
B - cell lymphoma of mucosa - associated lymphoid tissue (
MALT lymphoma ) to
diffuse large B - cell lymphoma (
DLBCL ) in 467
patients ( median age , 61 years ) . -
pubmed
A 47 - year - old
woman developed a
headache and
tinnitus in her right ear followed by sudden - onset
left hemiparesis . -
pubmed
A
dural arteriovenous fistula may be detected in
patients with
cerebral venous sinus thrombosis during the chronic phase . -
pubmed
RESULTS : In the 23 PIL
patients ,
diffusive large B cell lymphoma (
DLBCL ) and
enteropathy - associated T cell lymphoma (
EATL ) were the primary histopathological types , accounting for 47.8 % and 43.4 % of the total
patients , respectively . -
pubmed
The aneurismal sign was found in 26.2 % ( 11/42 ) lesions , more commonly seen in the
patients with
DLBCL than in those with
EATL ( chi2=8.101 , P=0.004 ) . -
pubmed
OBJECTIVE : To assess the effect of
neuroblastoma (
NB ) on the intestinal microbiome , metabolism , and inflammatory parameters in a
murine model . -
pubmed
Following 10 weeks of
tumor growth , all
animals were sacrificed to collect total white adipose tissue ( WAT ) . -
pubmed
CONCLUSIONS : The present study provides a first glimpse that
human NB in a
murine model induces
tumor cachexia associated with alterations in metabolic and inflammatory parameters , as well as changes in the intestinal microbiota . -
pubmed
Since the intestinal microbiome is known to contribute to the host 's ability to harvest energy , a favorable modulation of the intestinal microbiome in
tumor patients could potentially represent a novel therapeutic target to prevent
tumor - associated cachexia . -
pubmed
Effects of a non - thermal plasma needle device on
HPV-16 positive
cervical cancer cell viability in vitro . -
pubmed
The current work reveals the effects of a non - thermal needle - shaped atmospheric - pressure plasma on the viability of an adherent
human cervical carcinoma cell line containing a
human papillomavirus type 16 (
HPV-16 ) provirus . -
pubmed
These findings reveal possibilities for NTP treatment of
HPV-16 infected
cervical cancers and indicate the importance of NTP parameters to treatment outcome . -
pubmed
Three of the six evaluated
strains showed levels of degradation of 32 , 26 and 47 % (
Polyporus tricholoma ,
Cilindrobasidium laeve and
Deconica citrispora , respectively ) after twelve days of cultivation in the presence of the xenobiotic . -
pubmed
METHODS : The study included
iNPH patients undergoing overnight monitoring of the pulsatile / static ICP in whom a biopsy was taken from the frontal cerebral cortex during placement of the ICP sensor . -
pubmed
Reference ( Ref ) biopsies were sampled from 13
patients who underwent brain surgery for
epilepsy ,
tumours or
cerebral aneurysms . -
pubmed
RESULTS :
iNPH patients responding to surgery ( n = 44 ) had elevated pulsatile ICP , indicative of
impaired intracranial compliance . -
pubmed
CONCLUSIONS :
Idiopathic normal pressure hydrocephalus patients responding to CSF diversion present with abnormal pulsatile ICP , indicative of
impaired intracranial compliance . -
pubmed
Treatment at high - volume facilities and academic centers is independently associated with improved survival in
patients with locally advanced
head and neck cancer . -
pubmed
CONCLUSIONS :
Patients with locally advanced
head and neck squamous cell carcinoma who are undergoing curative radiotherapy at HVFs and academic centers appear to have improved survival . -
pubmed
Mouse models were made out of a
relapsed cervical cancer patient 's
tumour sample for original and recurrent
cervical cancer , and gene analysis in both
tumours and exosomes in these
mouse models were performed . -
pubmed
A retrospective observational study based on usual clinical practice was conducted in
patients attending the ED due to
low back pain during a period of 24 months . -
pubmed
A total of 732
patients who requested medical assessment due to
back pain in the ED of our hospital were analyzed , 91 of whom were treated with
tapentadol whereas 641 received another treatment . -
pubmed
Patients who received
tapentadol also had a better clinical evolution of
pain compared to those who did not receive it ( P & lt ; 10 ) and to those who received
tramadol ( P & lt ; 10).In this study in
patients with
back pain ,
tapentadol shows clear advantages over the other analgesics analyzed , in terms of
pain control and less need for reassessments . -
pubmed
Methods : In this cross - sectional case - control study , 77 eyes of 58
patients were divided into three groups : a first group ( n = 34 ) encompassed eyes with resolved
DME ( R - DME ) , a second group ( n = 24 ) corresponded to
diabetic eyes without
DME ( no - DME ) , and a third group ( n = 19 ) comprised a control group of nondiabetic healthy eyes . -
pubmed
VA was significantly correlated with EZ reflectivity in
diabetic patients ( r2 = 0.57 ; P & lt ; 0.0001 ) . -
pubmed
CASE PRESENTATION : A case of a 15 - year - old
boy is reported who presented with severe
systemic inflammation ,
perimyocarditis and
cardiogenic shock , in whom
EGPA was initially suspected and later diagnosed with
autoimmune adrenalitis with
PGA . -
pubmed
BACKGROUND : Frequent blood
glucose readings are the most cumbersome aspect of
diabetes treatment for many
patients . -
pubmed
Inference of emergent
cattle pastoralism in the southern Sahara desert based on localized
hypoplasia of the primary canine . -
pubmed
Here , we consider the effects of this dietary transition on early childhood health by examining localized
hypoplasia of the primary
canine ( LHPC ) . -
pubmed
We focus on the Gobero region of Niger which preserves cemeteries containing
skeletal remains from two occupation phases : ( 1 ) an Early Holocene / Kiffian fisher - forager phase , and ( 2 ) a Middle Holocene / Tenerian
cattle pastoralism phase . -
pubmed
METHODS : Clinical data from 236
patients with
acute leukemia accompanied by
bacterial bloodstream infection during July 2014 to November 2017 were retrospectively analyzed , 236
patients were divided into 5 groups ( & lt;0.05 ng / ml , 0.05- & lt;0.5 ng / ml , 0.5- & lt;2.0 ng / ml , 2.0- & lt;10.0 ng / ml and & gt;10.0 ng / ml ) according to PCT concentrations . -
pubmed
After SRT de novo
urinary incontinence complaints ( grade & gt;= 1 ) occurred in the respective acute and late phase in 6.1 % and 17.6 % of
patients . -
pubmed
METHODS : A total of 303
TNBC patients who underwent weekly
paclitaxel plus
carboplatin treatments followed by surgical resection were included in this study . -
pubmed
Correction to : Biodiversity and selection for
scrapie resistance in
sheep : genetic polymorphism in eight breeds of Algeria . -
pubmed
Roscoe Leaves , Methanolic Extract and
Guaijaverin on Blood
Glucose and Lipid Levels in a
Type II Diabetic Rat Model . -
pubmed
Oral acute treatment of
streptozotocin (
STZ)-induced
diabetic rats for 18 h with the
C. - pubmed
Recent transcriptome studies of the
infection of
maize by the biotrophic pathogen
Ustilago maydis are providing molecular insights into an ordered program of changes in gene expression and the deployment of effectors as well as key features of nutrient acquisition . -
pubmed
Hypothyroidism in
patients with
hepatocellular carcinoma receiving
cabozantinib : an unassessed issue . -
pubmed
Antibiotics are associated with decreased progression - free survival of advanced
melanoma patients treated with immune checkpoint inhibitors . -
pubmed
Conclusion : These findings suggest that
ATB use within 30 days prior to ICI initiation in
patients with advanced
melanoma may adversely affect
patient outcomes . -
pubmed
GdNPs solution which consists of 20 mg / mL
NaGdF4 was injected into a
nude mouse and two
tumor - bearing
mice . -
pubmed
METHODS : A total of 176
men with unilateral
inguinal hernia were randomized into two groups . -
pubmed
BACKGROUND : Metal sensitivity as a cause for painful joint replacement has become increasingly prevalent ; however , there is a lack of reported clinical outcome data from total knee arthroplasty
patients with
metal allergies . -
pubmed
Following revision ,
patients returned to the clinic at an interval of 6 weeks , 5 months , and 12 months for functional ,
pain , and satisfaction assessment . -
pubmed
CONCLUSIONS :
Patients presenting with a painful knee arthroplasty and positive metal LTT have improved
pain scores , walking function , and range of motion following revision to a hypoallergenic component . -
pubmed
Patients suffering from
polycystic liver disease may develop Hepatic Venous Outflow Obstruction ,
Portal Vein Obstruction and/or
Inferior Caval Vein Syndrome because of cystic mass effect . -
pubmed
fatty and fibrotic infiltration ) are a common feature in
individuals with lumbar spine pathology associated with
low back pain , which often result in functional loss . -
pubmed
CONCLUSIONS : There is increased fibrogenic gene expression in
individuals with
chronic disease when compared to
acute disease , without significant differences in atrophic , myogenic , adipogenic , or inflammatory pathways , suggesting increased efforts should be made to prevent or reverse fibrogenesis in order to improve
patient function in this population . -
pubmed
Decompression for recurrent
carpal tunnel syndrome provides significant functional improvement and
patient satisfaction . -
pubmed
Participants with
FM ( n=148 ) will undergo a conditioning exercise period and be randomly allocated to one of four groups : ( 1 ) active tDCS and AE , ( 2 ) sham tDCS and AE , ( 3 ) active tDCS and non - aerobic exercise ( nAE ) or ( 4 ) sham tDCS and nAE . -
pubmed
RESULTS :
Sarcopenia was diagnosed in 27
patients ( 51.9 % ) . -
pubmed
BACKGROUND : We present a rare case of
neonatal cholestasis in a female
infant with
Gaucher Disease (
GD ) , who received liver transplantation . -
pubmed
Despite early initiation of ERT , the
patient had worsening of her
liver failure and underwent a left lateral segment liver transplant from a living donor at 7 months of age . -
pubmed
METHODS : The medical records of all 40
patients who received palliative radiotherapy for malignant
ESCC from 2015 to 2017 were reviewed to determine the time course of key National Comprehensive Cancer Network guideline - supported workup and management steps . -
pubmed
RESULTS :
Patients treated for malignant
ESCC after our QI intervention were more likely to undergo magnetic resonance imaging ( MRI ) of the entire spine ( 64 % v 44 % ; P = .013 ) and have a radiation oncology ( RO ) consultation before surgery ( 100 % v 27 % ; P = .002 ) . -
pubmed
On subgroup analysis , initial trends toward delays in RO consultation for
patients planning for surgery ( median , 3 days ) or for lack of prior
cancer diagnosis ( median , 4 days ) were reduced to delays of 0 and 1 day , respectively , after the QI intervention . -
pubmed
[ Clinical analysis of maxillofacial
adipocytic neoplasia in
children ] . -
pubmed
Objective : To explore the clinical manifestations , diagnosis , treatment and prognosis of maxillofacial
adipocytic neoplasia in
children . -
pubmed
Methods : The clinical data of 8
children with maxillofacial
adipocytic neoplasia admitted to Shanghai Children 's Hospital from August 2014 to July 2019 were retrospectively analyzed , including 6
males and 2 females , aged from 8 months to 8 years 11 months , with an average age of 44 months . -
pubmed
Results : Among the 8
patients , 5 were
lipomas and 3 were
lipoblastomas ; 4 were in the masseter muscle region of the parotid gland , 2 were in the parapharyngeal space and 1 was in the submandibular and nasal areas separately . -
pubmed
All of 8
patients underwent surgical treatment without complications such as
infection , facial
paralysis , and
salivary fistula . -
pubmed
Conclusions :
Lipoma and
lipoblastoma are the main
tumors of maxillofacial
adipocytic neoplasia in
children . -
pubmed
The CAM6
strain showed in vitro antibacterial activity against selected enteropathogenic bacteria (
Escherichia coli strain NBRC 102203 and
Salmonella enterica serovar Typhimurium 4.5.12 ) and commensal bacteria (
Klebsiella pneumoniae ATCC BAA-1705D-5 and
Pseudomonas aeruginosa ATCC 15442 ) and resistance to all antibiotics except
amoxicillin . -
pubmed
Secondary aim was to evaluate impact of interventional radiology ( IR ) on delivery outcomes in
patients with
IP at MRI . -
pubmed
METHODS : Twenty - six
patients ( mean age 36.24y / o , SD6.16 ) with clinical risk - factors and echographic suspicion of
IP underwent 1.5T - MRI . -
pubmed
BACKGROUND : Diagnosis of soil - transmitted helminths (
STHs ) in developing countries is commonly based on microscopic detection of eggs in stool samples , using the Kato - Katz ( KK ) method , which has a poor sensitivity for detecting light intensity
infections . -
pubmed
We compared the performance of the KK method and real - time PCR in the framework of a randomized trial , which evaluated four novel treatments against
Trichuris trichiura and concomitant
STH infections . -
pubmed
We report two cases of
children who underwent emergent intubation for acute
respiratory distress due to viral
laryngotracheobronchitis and subsequently developed anterior laryngeal webs . -
pubmed
We aimed to summarize reliable medical evidence by the meta - analysis of all published clinical trials that investigated the safety , tolerability , and immunogenicity of vaccine candidates against
coronavirus disease 2019 ( COVID-19 ) , caused by
severe acute respiratory syndrome coronavirus 2 (
SARS - CoV-2 ) . -
pubmed
Curcuminoids , as potential phytochemicals extracted from
Curcuma Longa L. , have been documented for their chemopreventive and antitumor activities against several types of
malignancies . -
pubmed
Chagas disease is caused by the protozoan parasite
Trypanosoma cruzi and affects over 6 million people worldwide . -
pubmed
Evaluation in a
mouse model of
chronic T. cruzi infection did not show parasite growth inhibition , highlighting the difficulties encountered when going from in vitro assays onto preclinical drug developmental stages . -
pubmed
A comparison of
amnesia that is produced by two intravenous sedation techniques commonly used to reduce
anxiety in ambulatory oral surgery
patients showed that both techniques induce high levels of safe , predictable
amnesia . -
pubmed
A combination of therapeutic modalities was studied in 38 consecutive
patients with
intra - abdominally disseminated carcinoma of the ovary . -
pubmed
Resection or destruction by electrocoagulation of all visible
tumor was possible in 12
patients . -
pubmed
For 18 of the remaining 26
patients in group 2 , elimination of all visible
tumor was not possible technically , and in eight
patients in group 3 , an irresectable
tumor was found . -
pubmed
Selective discrete intraaxoplasmic deposits of
hydroxyapatite crystallites were observed in adult male
rats subjected to experimental
trauma to the lumbosacral spinal cord . -
pubmed
[ Scintigraphic course control in
children with
pyelonephritis ( proceedings ) ] . -
pubmed
Effects of
hypoxia and
glucose - free solution on the isolated
rat portal vein were studied . -
pubmed
[ Ultrastructure of neurosecretory cells of a
ganglion of the ventral nervous chain of
Eisenia foetida ( Sav . ) -
pubmed
Peripheral blood mononuclear cells ( PBMCs ) from
patients with
Chediak - Higashi syndrome (
CHS ) exhibit minimal natural - killer - like
cytotoxicity by standard
51Cr - release assays in vitro . -
pubmed
concentrations in 16
patients with
ARF and 12 healthy controls . -
pubmed
CLINICAL FEATURES : Two
patients who had been taking
nitrofurantoin for several years , presented with severe
liver failure . -
pubmed
A third
patient presented with acute
hepatitis after six weeks of
nitrofurantoin therapy . -
pubmed
INTERVENTION AND OUTCOME : One of the
patients with
liver failure died and the other underwent a successful liver transplantation . -
pubmed
Thirty
patients with bedpartners complaining of their heavy
snoring which had resulted in separate bedrooms were treated surgically . -
pubmed
These 184
patients made up the study group and age , gender ,
injuries , Injury Severity Score ( ISS ) , ventilator days ( VD ) , complications , length of stay ( LOS ) , and outcome were noted . -
pubmed
Genetic control of
delayed type hypersensitivity to
Mycobacterium leprae antigen . -
pubmed
The mechanism of genetic control of
Mycobacterium leprae - specific
delayed type hypersensitivity (
DTH ) in
mice was investigated in terms of footpad swelling response . -
pubmed
Studies with various congenic and recombinant inbred
strains of
mouse revealed that
M. - pubmed
Serum lipoprotein profile in
children with
celiac disease . -
pubmed
To determine lipoprotein production in states of
enterocyte dysfunction , we compared the serum lipid profiles in a group of 12
children with untreated
celiac disease ( flat jejunal mucosa ) with the profiles in a control group of 10
children suffering from other
intestinal diseases . -
pubmed
Seven cases of
occlusive ocular vascular disease affecting retinal and choroidal vessels were found among 84 consecutive
patients with raised levels of anticardiolipin antibodies attending the
lupus arthritis clinic at St Thomas 's Hospital from 1985 to 1987 . -
pubmed
Characterization of growth parameters of a
human hepatoma cell line cultured under serum - free conditions . -
pubmed
In this paper the growth of
PLC / PRF / 5 human hepatoma cell line in a serum- and hormone - free medium was investigated . -
pubmed
The influence of
starvation and natural refeeding on the rate of
triacylglycerol /
fatty acid substrate cycling in brown adipose tissue and different white adipose sites of the
rat in vivo . -
pubmed
A comparative study of results in
patients with
schistosomiasis and
cirrhosis . -
pubmed
Endoscopic sclerotherapy for
bleeding esophageal varices was carried out in 78
patients with
schistosomiasis ( Group I ) and 71 cirrhotic
patients ( Group II ) . -
pubmed
Throughout a follow - up period of at least 24 months ,
hemorrhage recurred in 13 % of the Group I
patients , with one
death ( 1 % ) . -
pubmed
A comparison of
patients with
schistosomiasis and
cirrhosis type A revealed no differences with respect to rebleeding or survival ( p greater than 0.05 ) . -
pubmed
Differences were significant for
bleeding recurrence and survival in Child B
patients as compared with
schistosomiasis patients ( p less than 0.025 ) . -
pubmed
This result suggests that macrophages play a regulatory role on LT production and release by regional lymph nodes in
human cancer . -
pubmed
[ Studies on the cell - mediated immunity in regional lymph nodes from
patients with
gastric cancer ] . -
pubmed
Plasma levels of
cortisol were sampled for 24 hours in 32 endogenously
depressed ( ED )
patients and 72 normal controls who also underwent the
dexamethasone suppression test . -
pubmed
Only seven
ED patients had means 24h PC values higher than 2 SDs from the normal mean ( greater than 10 micrograms / dL ) . -
pubmed
The mean plasma level of
cortisol between 1 and 4 PM was found to be highly correlated with the means 24h PC value in ED
patients , as has been previously reported in normal subjects and
patients with various other diseases ( in which it also powerfully discriminated between
hypersecretors and normosecretors ) . -
pubmed
In a prospective study , 20
patients with a first acute
myocardial infarction and no current treatment with diuretics or cardioactive drugs were randomized to treatment with intravenous
timolol ( 10
patients ) or placebo ( 10
patients ) . -
pubmed
Effect of
angiotensin on water and
electrolyte excretion in normal and
cirrhotic rats . -
pubmed
Proceedings :
Cadmium poisoning effects on the
rat dental tissues and bones . -
pubmed
Mortality of
diabetic patients treated surgically for
lower limb infection and or
gangrene . -
pubmed
[ Course of
chronic renal insufficiency in
patients receiving a long - term low - protein diet ] . -
pubmed
Rotavirus infection was frequently observed in
pigs that were two to six weeks old and was rare in younger animals . -
pubmed
Sucking
pigs less than two weeks old appeared to be protected from the
infection by passive immunity ; no antibodies were detected in the two- to three - week - old group , coinciding with an increased susceptibility to
rotavirus infection . -
pubmed
The antigenic specificity of the
rotavirus isolates was confirmed by enzyme - linked immunosorbent assay test , using antibodies directed against the group - specific antigen of
human rotavirus . -
pubmed
To study the relationship between fiber size and vulnerability to
ischemia , we produced partial
infarction of the proximal posterior tibial nerve of
Wistar rats by injecting
arachidonic acid into the ipsilateral femoral artery . -
pubmed
One hundred thirty - six
patients underwent thrombolytic therapy for acute evolving
myocardial infarction from June , 1981 , through December , 1982 . -
pubmed
Postoperative
hemorrhagic problems were minimal , and the incidences were no different from those for other coronary bypass
patients . -
pubmed
We injected antibacterial solutions into
rabbit pericardium to investigate
tissue injury . -
pubmed
Growth of pre - B cells in cultures of bone marrow from
children with
acute lymphoblastic leukaemia and other diseases . -
pubmed
Pre - B cells from the bone marrow of
children with
acute lymphoblastic leukaemia (
ALL ) survived up to 144 hr after the completion of treatment and divided in culture with maximum cell numbers at 24 hr . -
pubmed
Pre - B cell numbers also increased in culture of morphologically normal marrows from treated and untreated
patients with
solid tumours , and probably in normal marrows from
patients with
non - malignant diseases . -
pubmed
Elective repair of
aneurysms has a low mortality , and 50 % of the
patients live for at least 5 years . -
pubmed
In 3
patients , 5 ears , the
stenosis was congenital ; in 1
patient , 1 ear , traumatic ; and in 1
patient , 2 ears , secondary to chronic external
otitis . -
pubmed
We evaluated , in 128
patients with recurrent
nephrolithiasis , the efficacy of special treatment programs for some of the common causes of
nephrolithiasis , chosen on the basis of their ability to correct underlying physicochemical and physiologic derangements . -
pubmed
Therapy included
sodium cellulose
phosphate for 18
patients with absorptive
hypercalciuria ,
thiazide diuretics for 27
patients with absorptive
hypercalciuria and for 10 with
renal hypercalciuria ,
orthophosphate for eight
patients with
hypophosphatemic absorptive
hypercalciuria ,
allopurinol for 21
patients with hyperuricosuric
calcium oxalate nephrolithiasis ,
thiazide and
allopurinol for 26
patients with absorptive
hypercalciuria with
hyperuricosuria , and high fluid intake and/or low
calcium diet for 22
patients with normocalciuric
nephrolithiasis . -
pubmed
A retrospective study of 192
patients centered on the outcome of
supraventricular arrhythmias after catheter ablation of the atrioventricular junction provided some useful information concerning the choice of pacing mode in these patients . -
pubmed
Strains of
Escherichia coli specifically modified in their respiratory chain have been used recently to re - evaluate the energetic efficiency of the bacterial respiration using chemostat cultures . -
pubmed
In the second part of our experiments we studied the influence of acute and chronic
hypoxia on the
ascorbic acid content in liver , adrenal , plasma , cerebrospinal fluid and brain in 18 - day - old
rats . -
pubmed
Typical patterns in the EEG of 5
children with
lissencephaly are presented . -
pubmed
To determine the relationship between nutritional status and
ethanol consumption , 250 chronically alcoholic
men ( mean age 41 + /- 11 years ) entering an
alcoholism treatment program were studied . -
pubmed
DESIGN : Plasma samples were collected from 94 normotensive and 93 essential
hypertensive subjects , the latter either previously defined by dietary salt sensitivity ( n = 43 ) , or prospectively studied on both low- ( & lt ; 50 mmol / day ) and high - salt ( & gt ; 200 mmol / day ) diets ( n = 16 ) . -
pubmed
Of these , 4 of 25 were from individuals infected with
human immunodeficiency virus (
HIV ) and 3 of 27 were not infected with
HIV . -
pubmed
Investigators have compiled extensive experience with
mitomycin in the treatment of
patients with
breast cancer . -
pubmed
Such regimens may yield quicker responses , and thus improve survival , in
patients with
breast cancer . -
pubmed
The retinas could be evaluated in all the examined
dogs , and revealed no abnormalities except for one case of
focal retinopathy . -
pubmed
Investigation of unknown
rashes in these
patients includes skin biopsy , which clearly differentiates
leukocytoclastic vasculitis and
erythema exsudativum multiforme with
lymphocytic vasculitis from cutaneous manifestations of
GvHD . -
pubmed
Special stains may reveal
bacteria and fungus in
septicemic patients . -
pubmed
It has been reported that the
F - Dopa ( FD ) uptake in
patients with
idiopathic Parkinson ' s disease (
PD ) decreased significantly in the caudate and putamen when compared to controls . -
pubmed
The FD uptake was measured by PET with
6 - L -[ 18F ] fluorodopa in 17
patients with
PD . -
pubmed
The caudate and the putaminal FD uptake ratios in the
patients with
PD decreased as their clinical stages advanced . -
pubmed
The FD / PET study therefore effectively demonstrated the severity of the clinical symptoms of
rigidity and
bradykinesia in
patients with
PD in correlation with a decrease in the FD uptakes in the caudate and the putamen , and it also demonstrated that the severity of
tremor might have a different mechanism from that of such other symptoms as
rigidity and
bradykinesia . -
pubmed
OBJECTIVE : An epidemiological study conducted between 1987 and 1989 in a single school district in the southeastern United States investigated the incidence , transition probabilities , and risk factors for
major depressive disorder (
MDD ) and
dysthymia in
adolescents aged 11 to 16 years . -
pubmed
METHOD : Diagnoses were based on the Schedule for
Affective Disorders and
Schizophrenia for School - Age
Children , which was administered to 247 mother - adolescent pairs at 12 - month intervals . -
pubmed
A retrospective study was conducted to describe airway intervention required to manage
patients with
craniofacial syndromes and
diseases involving the midface and mandible ( i.e. -
pubmed
Calf veins are one of the most common sites for
deep vein thrombosis (
DVT ) but the management of
patients with
calf vein thrombosis differs . -
pubmed
A study was carried out where 50
patients with isolated
calf vein thrombosis were followed over a one year period to determine the long term outcome in the calf veins . -
pubmed
Data from 400 consecutive elective ambulatory operations for
inguinal hernia under unmonitored local anaesthesia with limited pre - operative testing were prospectively obtained by the use of standardised files and questionnaires to assess the feasibility ,
patient satisfaction and potential cost reductions for such a technique . -
pubmed
Cardioversion , usually by transthoracic direct current
shock , restores
sinus rhythm in & gt ; 80 % of
patients , but
recurrence of
AFib over the weeks and months that follow decreases the value of this strategy . -
pubmed
In this study , we assessed the effect of chronic
alcohol ingestion on bacterial clearance , survival , and cytokine mRNA and protein expression in
mice with Klebsiella
pneumonia . -
pubmed
Effects of
birth weight and postnatal nutrition on neonatal
sheep : I. -
pubmed
CT bone density was determined using the OsteoQuant in 14
individuals with
OI - type I who ranged in ages from 8 months to 45 years . -
pubmed
falciparum
infection rates and density , whereas
P. - pubmed
Susceptibility of chacma baboons (
Papio ursinus orientalis ) to
infection by hepatitis B virus . -
pubmed
BACKGROUND : Because
baboons are being considered as a source of xenografts for
human liver transplantation in
patients with
hepatitis B virus- (
HBV ) induced
cirrhosis to forestall
infection of the graft by the virus , we undertook a study to ascertain if
baboons are resistant to
HBV infection . -
pubmed
METHODS : Six chacma baboons were inoculated with serum containing
HBV and were followed for 52 weeks to detect transmission of
infection . -
pubmed
CONCLUSIONS :
Chacma baboons are susceptible to
HBV infection and appear to develop a chronic carrier state . -
pubmed
The use of xenografts from baboons should preferably be avoided , but if they are used again for
HBV - infected patients it would be prudent to treat the patients as if they had received an organ from a
human donor . -
pubmed
Temporal lobe asymmetry in
patients with
Alzheimer ' s disease with
delusions . -
pubmed
Temporal asymmetry was computed as the right / left ( R / L ) ratio of the WTH in 22 non - delusional and 19 delusional
patients with
Alzheimer ' s disease . -
pubmed
Delusional
patients had
paranoid delusions ( of theft , jealousy , persecution ) . -
pubmed
None of the
patients had misidentifications or other
delusions of non - paranoid content . -
pubmed
Enoxaparin reduces
brain edema ,
cerebral lesions , and improves motor and
cognitive impairments induced by a
traumatic brain injury in
rats . -
pubmed
Enoxaparin , a low - molecular weight
heparin , which is efficacious in models of
myocardial and brain ischemia was studied in lateral fluid percussion - induced
TBI in
rats . -
pubmed
Therefore ,
enoxaparin could be a candidate drug to treat
acute brain - injured patients . -
pubmed
In comparison to primary
wound closure with local tissue , the technique presented in this study reduces the severity of
postoperative pain and allows faster rehabilitation in
patients because of a better
wound - healing process . -
pubmed
BACKGROUND : It remains unknown whether there is any important clinical advantage to the use of either a bioprosthetic or mechanical valve for
patients with native or
prosthetic valve endocarditis . -
pubmed
METHODS : Between 1964 and 1995 , 306
patients underwent valve replacement for left - sided native ( 209
patients ) or prosthetic ( 97
patients ) valve
endocarditis . -
pubmed
Long - term survival was superior for
patients with native valve
endocarditis ( 44+/-5 % at 20 years ) compared with those with
prosthetic valve endocarditis ( 16+/-7 % at 20 years ) ( p & lt ; 0.003 ) . -
pubmed
Outcome of
cataract surgery in
patients with
retinitis pigmentosa . -
pubmed
METHODS : A retrospective analysis was undertaken of a continuous series of 142 eyes of 89
patients with
retinitis pigmentosa undergoing
cataract surgery between 1985 and 1997 . -
pubmed
CONCLUSIONS :
Cataract surgery for relatively minor
lens opacities is beneficial in
patients with
retinitis pigmentosa , and most report subjective improvement of
visual symptoms . -
pubmed
Like the two U.S.
strains of
human HEV , an extra G residue immediately proceeding the poly(A ) tail was identified in
swine HEV . -
pubmed
The 5 ' NCR of
swine HEV also differed from many
HEV strains : it lacks an A residue at its 5 ' very end , and the extra 9 nucleotides in the US-2
strain . -
pubmed
In the 3 ' NCR ,
swine HEV shared 90 - 91 % nucleotide sequence identities with the US-1 and US-2
strains but only about 58 - 65 % identities with other
HEV strains . -
pubmed
This study further suggests that the US-1 and US-2
strains of
human HEV may be of
swine origin . -
pubmed
Double - blind , placebo - controlled study of
L - carnosine supplementation in
children with
autistic spectrum disorders . -
pubmed
We investigated 31
children with
autistic spectrum disorders in an 8 - week , double - blinded study to determine if 800 mg
L - carnosine daily would result in observable changes versus placebo . -
pubmed
After 8 weeks on
L - carnosine ,
children showed statistically significant improvements on the Gilliam
Autism Rating Scale ( total score and the Behavior , Socialization , and Communication subscales ) and the Receptive One - Word Picture Vocabulary test ( all P & lt ; .05 ) . -
pubmed
We present a
patient who suffered from
sleep attacks after starting
entacapone in addition to
levodopa . -
pubmed
Preliminary studies have demonstrated a significant reduction in
SRMD bleeding for
patients receiving PPI prophylaxis . -
pubmed
PPIs may become an effective tool for reducing the incidence of
SRMD in
critically ill patients . -
pubmed
The use of acute normovolemic
hemodilution in
patients undergoing cardiac surgery . -
pubmed
To test this hypothesis , we analyzed invasive recordings from
epileptic patients while they performed a spatially immersive , virtual taxi driver task . -
pubmed
[
Airway hyperreactivity in
patients with
allergic and non - allergic rhinitis ] . -
pubmed
Asthma can affect 40 % of the
patients with
rhinitis and 80 % of
asthmatics present
rhinitis . -
pubmed
OBJECTIVE : To determine if there is bronchial hyper - responsiveness in
patients with allergic and not
allergic rhinitis , by correlating with the
eosinophilia in nasal mucosa . -
pubmed
Twenty - eight
patients concluded the study , they were divided in two groups : a group of 15
patients with diagnosis of
allergic rhinitis and another group of 13
patients with diagnosis of
non allergic rhinitis . -
pubmed
RESULTS : Fifty - six spirometry studies were performed and only 4
patients ( 26.6 % ) with diagnosis of
allergic rhinitis presented fall of the FEV1 in the bronchial challenge in comparison with the group of non
allergic rhinitis in which there were no changes in the FEV1 later to the bronchial challenge . -
pubmed
CONCLUSIONS : Nonspecific bronchial hyper - responsiveness is present in
patients with
allergic rhinitis . -
pubmed
[
Human listeriosis . -
pubmed
Dose - dense regimen of
temozolomide given every other week in
patients with
primary central nervous system tumors . -
pubmed
BACKGROUND :
Temozolomide has shown activity and limited
toxicity in
patients with primary
brain tumors at doses of 150 - 200 mg / m(2)/day on days 1 - 5 every 4 weeks . -
pubmed
In this study , a new alternative dose - dense regimen of
temozolomide was explored in
patients with recurrent
brain tumors . -
pubmed
PATIENTS AND METHODS : In this study , we evaluated the safety , dose - limiting
toxicity , maximum tolerated dose , recommended dose and activity of
temozolomide given on days 1 - 3 and 14 - 16 every 28 days ( one cycle ) . -
pubmed
The starting daily dose was 200 mg / m(2 ) in a group of at least six
patients , with subsequent increments of 50 mg / m(2 ) in groups of at least 12
patients until unacceptable
toxicity was reached . -
pubmed
RESULTS : Seventy
patients with
brain tumors entered this study . -
pubmed
Grade 3 - 4
thrombocytopenia was observed in 0/7 , 1/13 , 5/38 and 4/12
patients treated at doses of 200 , 250 , 300 and 350 mg / m(2)/day , respectively . -
pubmed
Grade 3 - 4
neutropenia was observed in 1/7 , 0/13 , 3/38 and 4/12
patients treated with 200 , 250 , 300 and 350 mg / m(2)/day
temozolomide , respectively . -
pubmed
At a dose of 350 mg / m(2 ) , sustained grade 2 - 3
thrombocytopenia did not allow treatment to be resumed at day 14 in & gt;40 % of
patients , and this dose was considered to be the maximum tolerated dose . -
pubmed
CONCLUSIONS :
Temozolomide can be given safely using a dose - dense regimen of 300 mg / m(2)/day for 3 consecutive days every 2 weeks in
patients with recurrent
brain tumors . -
pubmed
OBJECTIVE : To study the relation between human
polyomavirus BK ( BKV ) infection and the risk of developing
nephropathy , we monthly investigated the
BKV load in urine and serum samples from 15 renal transplant recipients during 6 months in relation with immunosuppressive treatment and renal function . -
pubmed
RESULTS : Fifty - three percent of the patients had quantifiable
BKV - DNA both in urine and serum samples but there was no relation between
viruria and
viraemia . -
pubmed
Seventy - five percent of the
patients on
FK506 therapy and 71.4 % of those on
CyA therapy showed activation of
BKV infection . -
pubmed
In ten
patients serum
creatinine levels were & lt;2 mg / dl for the whole study , even if 80 % presented
BKV viruria and/ or
viraemia . -
pubmed
On the other hand , in 4
patients serum
creatinine levels reached higher values , but they were
BKV viruria and/or
viraemia negative during the study . -
pubmed
CONCLUSIONS : Our results suggest that
viruria and
viraemia may reflect independent
BKV reactivation in different tissues . -
pubmed
We aimed to determine whether an individualized course of
dexamethasone given to preterm
babies at risk of
chronic lung disease reduced the total dose of
dexamethasone administered and reduced side - effects compared with a standard 42 - day course . -
pubmed
CONCLUSION : The individualized course of
dexamethasone used in this study reduced the total dose of
dexamethasone administered but did not significantly reduce side - effects of treatment or alter outcome in
infants at risk of
chronic lung disease . -
pubmed
High sensitivity of
northern pike larvae to UV - B but no UV - photoinduced
toxicity of
retene . -
pubmed
However ,
pike larvae were very sensitive to UV - B even in low doses , indicated as severe
neurobehavioral disorders . -
pubmed
Monitoring of
pike with the
neurobehavioral syndrome revealed substantial late mortality . -
pubmed
In this study , in which 12 - day - old
mouse embryos were used because of a high frequency of " natural cell
death " due to changing inner ear morphology [ Kaufman , M.H. -
pubmed
PATIENTS AND METHODS : Between January 1999 and August 2002 , 43
patients undergoing laparoscopic GB for morbid
obesity underwent upper gastrointestinal endoscopy , 24 - hour pH monitoring , and stationary esophageal manometry before GB and between 6 and 18 months postoperatively . -
pubmed
A few
patients developed massive
postoperative reflux . -
pubmed
Patients presenting to emergency departments after
cocaine ingestion frequently present with a chief complaint of
chest pain . -
pubmed
RESULTS : The binding potential of
[ 11C ] d - threo - methylphenidate was reduced in the striatum in
SCA2 and
SCA3 ; in contrast to
patients with
Parkinson disease , no increased susceptibility of the putamen was evident . -
pubmed
A trend toward increased regional cerebral
glucose metabolism was found in the temporal cortex of all
patients with
SCA , pronounced in
SCA6 . -
pubmed
Non - coplanar
PCB - mediated modulation of
human leukocyte phagocytosis : a new mechanism for
immunotoxicity . -
pubmed
CMD : a
Cotton Microsatellite Database resource for Gossypium genomics . -
pubmed
Exercise - induced
myocardial ischemia in a
patient with dislocated right coronary artery orifice in the
right sinus of Valsalva . -
pubmed
In db / db and HFD
mice , gene transcripts associated with mitochondrial
ATP production , energy uncoupling , mitochondrial ribosomal proteins , outer and inner membrane translocases , and mitochondrial heat -
shock proteins were decreased in abundance , compared with db/+ and standard - fat diet - fed control
mice , respectively . -
pubmed
Adipose mitochondrial biogenesis was overwhelmingly suppressed in both
mouse models of
diabetes /
obesity and globally induced by
RSG . -
pubmed
METHODS : The cases of 106
patients with
osteochondritis dissecans of the capitellum were studied retrospectively . -
pubmed
Acidosis and lipopolysaccharide from
Escherichia coli B:055 cause hyperpermeability of rumen and colon tissues . -
pubmed
Atypical
dermatophilosis of
sheep in Kenya . -
pubmed
Clinical diagnosis of
ovine dermatophilosis was made and confirmed by direct microscopic examination as well as isolation and identification of
Dermatophilus congolensis from scab material from the affected
sheep . -
pubmed
The paper highlights atypical
dermatophilosis of
sheep and we believe that this is the first published report of an outbreak of ovine
dermatophilosis in Kenya . -
pubmed
BACKGROUND : Despite disproportionately high rates of
hepatitis C (
HCV ) among patients with severe
mental illness , to date , there is scant empirical data available regarding antiviral therapy outcomes within this population . -
pubmed
OBJECTIVE : To compare antiviral therapy completion and response rates between
HCV patients with vs those without
schizophrenia (
SCHZ ) . -
pubmed
All patients confirmed to have
SCHZ and to have received antiviral therapy between 1998 and 2006 ( n = 30 ) were compared with a control group of demographically matched (
HCV genotype , age , race , gender ) patients with no history of
SCHZ ( n = 30 ) . -
pubmed
CONCLUSION : Our retrospective chart review suggests that patients with
SCHZ complete and respond to antiviral therapy for
HCV at rates comparable with those without SCHZ . -
pubmed
High prevalence of
neuropathy in
patients with impaired 60 - minute oral
glucose tolerance test but normal fasting and 120 - minute
glucose levels . -
pubmed
Polyneuropathy was found in 44.4 % , 28.5 % , and 50.0 % of
patients with
IGT ,
IFG and
DM respectively . -
pubmed
The prevalence of
polyneuropathy was significantly higher in
patients with impaired 60 - min than OGTT normal subjects ( 52.4 % vs 21.7 % p=0.003 ) . -
pubmed
CONCLUSION : Since the prevalence of
neuropathy in
patients with impaired 60 - min
glucose levels is high , it would be valuable to look at 60 - min
glucose levels to detect
abnormal glucose metabolism and the
neuropathy earlier in the course . -
pubmed
We conducted a retrospective study comparing 450 consecutive
patients with full - thickness
gastric injury with 983
patients without
gastric injury during the same time period . -
pubmed
[
Brain abscess due to
Mycobacterium tuberculosis ] . -
pubmed
METHODS : The subjects were 22 healthy
volunteers and 10
patients with proton - pump inhibitor ( PPI ) dependent
gastroesophageal reflux disease (
GERD ) . -
pubmed
RESULTS : The mean primary peristaltic amplitude associated with swallowing was 65.6+/-47.4 mmHg in the
volunteer group , and 28.0+/-25.6 mmHg in the
GERD group . -
pubmed
OBJECTIVE : Joint - preserving osteotomies in
patients with symptomatic
varus malalignment of the ankle . -
pubmed
RESULTS : Twelve
patients with an osteotomy of the distal tibia presented with a significant reduction of
pain on a visual analog scale ( p = 0.0001 ) and an increased range of motion of 33 degrees ( 5 - 55 degrees ) preoperatively compared to 39 degrees ( 25 - 50 degrees ) postoperatively . -
pubmed
All 18
patients treated with a Z - shaped calcaneal osteotomy reported
pain relief with osseous consolidation after 6 months . -
pubmed
We report a 43 - year - old
woman with
PCALCL who had generalized
skin involvement accompanied by involvement of one peripheral draining lymph - node region . -
pubmed
Tumor reduction rate predicts early
recurrence in
patients with
breast cancer failing to achieve complete response to primary chemotherapy . -
pubmed
The correlation between
tumor reduction rate derived from MRI and occurrence of early events in
breast cancer patients was analyzed retrospectively . -
pubmed
CONCLUSIONS : The evaluation of
tumor reduction rates on MRI was considered to be useful for predicting early outcome among
breast cancer patients who can not achieve pCR after PCT . -
pubmed
Treatment of
patients with
keratoconjunctivitis sicca with Optive : results of a multicenter , open - label observational study in Germany . -
pubmed
OBJECTIVE : To evaluate the efficacy and tolerability of Optive , a new
dry eye product containing sodium carboxymethylcellulose ( 0.5 % ) and
glycerol ( 0.9 % ) , in
patients with
keratoconjunctivitis sicca (
KCS ) . -
pubmed
METHODS : This was a non - interventional and observational study including
patients with
dry eye who required a change of medication or were naive to dry eye treatment ( N = 5,277 ) . -
pubmed
RESULTS : The severity of
KCS was mild in 18.6 % , moderate in 59.9 % , and severe in 21.5 % of
patients based on physicians ' assessment . -
pubmed
STUDY DESIGN : Eighty - five Thai subjects ( 29
men , 56
women ) who had
MetS according to the International Diabetes Federation definition were evaluated for
CAC detected on panoramic radiographs . -
pubmed
CONCLUSION : Thai
people with
MetS have high prevalence of radiographically detectable
carotid artery calcifications . -
pubmed
The most common diagnosis leading to
cardiac arrest was
acute myocardial infarction ( 46 of 135
patients ) . -
pubmed
INCIDENCE OF
GASTRIC ULCER IN ALBINO
RATS FED DIETS DEFICIENT IN
VITAMIN B ( B ( 1 ) ) . -
pubmed
73 per cent of a group of
albino rats whose diet was deficient in
vitamin B have been found to have
ulcerations of the gastric mucosa . -
pubmed
Of 74 observed lesions eight were chronic , indurated
ulcers resembling
chronic peptic ulcer in
man . -
pubmed
Ectopic
human mesenchymal stem cell - coated scaffolds in
NOD / SCID mice : an in vivo model of the
leukemia niche . -
pubmed
When implanted subcutaneously in
NOD / SCID mice , these niches supported engraftment of primary
human acute myeloid leukemia cells . -
pubmed
To better understand the evolution of
CIV since its emergence , and particularly its microevolution in spatially restricted populations , we examined multiple gene segments of
CIV from
dogs resident in two large animal shelters in New York City during the period 2006 to 2009 . -
pubmed
METHODS : We describe an elderly , yet healthy
man who sought medical attention for
subarachnoid hemorrhage . -
pubmed
DESIGN : We retrospectively studied 30 consecutive cases of histologically proven
rhabdomyosarcoma in
children aged 0 - 15 years extracted from the database of the Cancer Registry of the Center of Tunisia for the period 1993 - 2007 . -
pubmed
RESULTS :
Rhabdomyosarcomas represented 53.6 % of
soft tissue sarcomas and 3.8 % of all
children cancer cases registered during this period . -
pubmed
The study included 686
children ( 2 - 16 years of age ) with presumed
AA managed by appendectomy . -
pubmed
RESULTS : Of the 686
children who underwent surgery for suspected
AA , 34 ( 5 % ) had a normal appendix ( negative appendectomy rate ) . -
pubmed
Children in the AA group were younger ( 10.9 + -3.2 vs. 12.1 + -2.3 years , p=0.004 ) , had higher
fever ( 36.9 + -0.7 C vs. 37.4 + -0.8 C , p=0.004 ) , WBC ( 14.8 + -4.8 vs. 10.5 + -4.6x103 / mL , p<0.0005 ) , and neutrophil counts ( 77.2 + -11.1 % vs. 64.0 + -15.9 % , p<0.0005 ) on admission , and larger appendicular diameters on ultrasound ( US ) examination ( 0.9 + -0.2 cm vs. 0.7 + -0.08 cm , p<0.0005 ) . -
pubmed
Effect of
body weight on the outcome of displaced intracapsular
fracture neck of femur treated by internal fixation ; a clinical study of 198
patients . -
pubmed
A total of 198
patients with such
injuries treated by closed reduction and internal fixation , were recruited retrospectively . -
pubmed
Patients were followed up until
fracture endpoint ( union or non - union ) with a minimum follow up of 100 days . -
pubmed
The mean
body weight for the 118
patients without
fracture healing complications was 64.6 kg versus 61.8 kg for the 80
patients with complications , a difference that was not statistically significant ( p=0.17 ) . -
pubmed
Temporal changes in the management and outcome of Canadian
diabetic patients hospitalized for non - ST - elevation
acute coronary syndromes . -
pubmed
Patients with
diabetes were older ; were more likely to have prior cardiac history including
myocardial infarction , revascularization , and
heart failure ; and had worse Killip class and higher GRACE risk score ( all P & lt ; .001 ) . -
pubmed
However ,
diabetic patients were less likely to undergo coronary angiography ( 52.5 % vs 57 % , P & lt ; .001 ) or revascularization ( 28.4 % vs 33.4 % , P & lt ; .001 ) . -
pubmed
Overall , compared with the group without
diabetes ,
diabetic patients had higher unadjusted rates of in - hospital mortality ( 3.0 % vs 1.6 % , P & lt ; .001 ) . -
pubmed
BACKGROUND AND PURPOSE : The European Cooperative
Acute Stroke Study ( ECASS ) III extended the thrombolysis time window for
patients with
stroke from 3 to 4.5 hours after symptom onset . -
pubmed
METHODS : The present study was based on a prospective database of 93 hospitals of the Stroke Register of Northwestern Germany , which included 91 805
patients with
ischemic stroke admitted between January 2007 and December 2009 . -
pubmed
The proportion of
patients with
stroke with a door - to - needle time<60 minutes increased after publication of ECASS III ( OR , 1.49 ; 95 % CI , 1.37 to 1.63 ) . -
pubmed
Speech and language delays in preschool
children . -
pubmed
Type 2 diabetes in obese
patients with
body mass index of 30 - 35 kg / m2 : sleeve gastrectomy versus medical treatment . -
pubmed
Our objective was to compare the effects of LSG and medical therapy on
patients with
T2DM and a
BMI of & lt;35 kg / m(2 ) . -
pubmed
METHODS : A total of 18 nonmorbidly obese
patients with
T2DM , diagnosed according to the American Diabetes Association guidelines , were consecutively enrolled . -
pubmed
RESULTS : In group A ,
T2DM resolution was achieved in 8 ( 88.8 % ) of the 9
patients (
T2DM duration 5.2 yr ) . -
pubmed
Hypertension was controlled in all 8 of 9
patients . -
pubmed
In 1
patient ,
obstructive sleep apnea syndrome improved . -
pubmed
In group B , all 9
patients continued to have
T2DM and required
hypertensive and hypolipemic therapies throughout the observation period . -
pubmed
At baseline , 3
patients were affected by
obstructive sleep apnea syndrome and remained affected 1 year later . -
pubmed
CONCLUSION : The results of the present study have confirmed the efficacy of LSG in the treatment of nonmorbidly obese
T2DM patients , with a remission rate of 88.8 % without undesirable excessive
weight loss . -
pubmed
A novel Gram - staining - negative , coccoid , non - motile bacterium , designated
strain V1 - 41(T ) , was isolated from a sample of marine sediment collected , at a depth of 200 m , from Kongsfjorden ( an inlet on the west coast of Spitsbergen , an island that forms part of the Svalbard archipelago in the Arctic Ocean ) . -
pubmed
In DNA - DNA hybridizations , however , the levels of relatedness between
strain V1 - 41(T ) and
O. - pubmed
litoralis
DSM 15406 ( T ) and between the novel
strain and
O. - pubmed
The type
strain is
V1 - 41(T ) ( = CCUG 58690(T ) = KCTC 23013(T ) = NBRC 106171(T ) ) . -
pubmed
In
obstructive sleep apnea patients , elevated activity of the lingual muscles during wakefulness protects the upper airway against occlusions . -
pubmed
A possibly related form of respiratory neuroplasticity is present in
rats exposed to acute and chronic intermittent
hypoxia (
CIH ) . -
pubmed
Early ultrasonographic finding of
septic thrombophlebitis is the main indicator of central venous catheter removal to reduce
infection - related mortality in neutropenic
patients with
bloodstream infection . -
pubmed
BACKGROUND :
Septic thrombophlebitis increases
patient morbidity and mortality following
metastatic infections ,
pulmonary emboli , and/or
septic shock . -
pubmed
Central venous catheter ( CVC ) removal for occult
septic thrombophlebitis challenges current strategy in
neutropenic patients . -
pubmed
PATIENTS AND METHODS : We prospectively evaluated
infection - related mortality in 100
acute leukemia patients , with CVC - related
bloodstream infection (
CRBSI ) after chemotherapy , who systematically underwent ultrasonography to identify the need for catheter removal . -
pubmed
Their
infection - related mortality was compared with that of a historical cohort of 100
acute leukemia patients , with
CRBSI after chemotherapy , managed with a clinically driven strategy . -
pubmed
RESULTS : In the prospective series , 30/100
patients required catheter removal for ultrasonography - detected septic
thrombophlebitis after 1 median day from
BSI onset ; 70/100 patients without septic
thrombophlebitis retained their CVC . -
pubmed
In the historical cohort , 60/100
patients removed the catheter ( persistent
fever , 40
patients ; persistent
BSI , 10
patients ; or clinically manifest
septic thrombophlebitis , 10
patients ) after 8 median days from
BSI onset ; 40/100 patients retained the CVC because they had not clinical findings of complicated
infection . -
pubmed
CONCLUSION : Ultrasonography is an easy imaging diagnostic tool enabling effective and safe management of
patients with
acute leukemia and
CRBSI . -
pubmed
Acinetobacter baumannii causes severe
infections in compromised patients , who present an
iron - limited environment that controls bacterial growth . -
pubmed
Nasolacrimal duct obstruction as a complication of
iodine-131 therapy in
patients with
thyroid cancer . -
pubmed
This study reports on symptomatic and asymptomatic
nasolacrimal duct obstruction (
NLDO ) as complications of high - dose
radioiodine therapy in these
patients . -
pubmed
METHODS : Eighty - one
cases were randomly selected from a population of
radioiodine - treated differentiated
thyroid carcinoma patients and were enrolled in a historical cohort study . -
pubmed
All the
patients were suffering from right
heart failure and
pulmonary hypertension , and the preoperative mean pulmonary artery pressure ( mPAP ) was 51.2 + /- 10.2 mmHg , and the pulmonary vascular resistance ( PVR ) was 894.2 + /- 207.7 dyne x sec(-1 ) x cm(-5 ) . -
pubmed
The
patients ' symptoms such as
shortness of breath , and
dyspnea improved and they were discharged without any serious complications . -
pubmed
We demonstrated that
animals exposed to cigarettes in the prenatal period had increased the risk for
psychotic symptoms in adulthood . -
pubmed
METHODS This study was carried out on fifty ( 50 )
patients with oral sub mucous
fibrosis . -
pubmed
[ Clinical features of antiviral therapy - induced
thyroid disease in
patients with
chronic hepatitis C ] . -
pubmed
OBJECTIVE : To investigate the clinical features of
thyroid disease occurring in response to antiviral therapy in
patients with
chronic hepatitis C (
CHC ) . -
pubmed
METHODS : Eighty - two
patients diagnosed with
CHC were recruited for study from our hospital between 2009 and 2010 . -
pubmed
Differential expression of biomarkers was assessed between
patients who developed
thyroid disorder and those who did not . -
pubmed
When the two groups of
patients who did or did not develop
thyroid disease were compared , there was no difference in the amount of
patients who achieved sustained virological response . -
pubmed
CONCLUSION : Antiviral - induced
thyroid disease in
patients with
refractory hepatitis C manifests as clinically - detectable abnormalities in serum levels of thyroid autoantibody and markers of
hypothyroidism . -
pubmed
Gold ( III )- dithiocarbamato peptidomimetics in the forefront of the targeted anticancer therapy : preclinical studies against
human breast neoplasia . -
pubmed
Among all , we focused on two compounds and tested them on
human MDA - MB-231 ( resistant to
cisplatin )
breast cancer cell cultures and xenografts , discovering the proteasome as a major target both in vitro and in vivo . -
pubmed
53 % inhibition of
breast tumor growth in
mice was observed after 27 days of treatment at 1.0 mg kg(-1 ) d(-1 ) , compared to control . -
pubmed
Remarkably , if only the most responsive
mice are taken into account , 85 % growth inhibition , with some animals showing
tumor shrinkage , was observed after 13 days . -
pubmed
BACKGROUND : There is a growing interest in measuring cerebral autoregulation in
patients with
acute brain injury . -
pubmed
METHODS : We performed 37 simultaneous recordings of BP and cerebral blood flow velocity in 15
patients with
acute brain injury . -
pubmed
Genes relevant with
osteoarthritis by comparison gene expression profiles of synovial membrane of
osteoarthritis patients at different stages . -
pubmed
BACKGROUND : This study aimed to identify biological markers about
osteoarthritis (
OA ) which is a
polygenic disease by investigating the gene expression profiles of the synovium samples from early - stage and end - stage
OA patients for the diagnosis and treatment of
OA . -
pubmed
METHODS : The gene expression profile of GSE32317 was downloaded from Gene Expression Omnibus ( GEO ) database , including 10 samples from early - stage
OA patients and 9 samples from end - stage
OA patients . -
pubmed
Two species of microalgae
Chlorella pyrenoidosa ,
Scenedesmus obliqnus and a
red worm Chironomidae larvae were selected as test organisms in determining the acute
toxicity effects of
Cr ( VI ) ,
2,4,6 - trichlorophenol and
nitrobenzene . -
pubmed
Numerous agents derived from
plants have anti -
gout potential . -
pubmed
In the rare
human studies ,
colchicine from
Colchicum autumnale showed anti - inflammatory effects while for other
plant extracts , although revealing anti -
gout potential , further phytochemical investigations are needed to identify their active constituents . -
pubmed
Besides , the
plants which give antioxidant activities are much potent in the management of
gout and need to be further investigated . -
pubmed
We recently reported the characteristics of a
HD patient - derived iPSC carrying 72 CAG repeats ( HD72 - iPSC ) . -
pubmed
In this study , we investigated the in vivo roles of HD72 - iPSC in the YAC128 transgenic
mice , a commonly used
HD mouse model carrying 128 CAG repeats . -
pubmed
METHODS : We recruited 357 qualified participants from consecutive
patients with
acute ischemic stroke who came to the
stroke registry center in Sichuan Provincial People 's Hospital , Chengdu , China . -
pubmed
In each subject , airway with conventional pure tone audiometry from 125 to 8000 Hz was assessed using a clinical audiometer ( model 622 , Minimate , Madsen ) Clinical case :
Hearing loss at all frequencies was found in all eight
patients , from mild to severe in both ears . -
pubmed
Clostridium difficile carriage in hospitalized
cancer patients : a prospective investigation in eastern China . -
pubmed
Vascular changes in the developing
rat retina in response to
hypoxia . -
pubmed
This study explored the effects of exemplar changes on visual object recognition in
patients with
schizophrenia and paired control subjects . -
pubmed
Overall , performance was better on the inclusion task than on the exclusion task ;
schizophrenia patients performed worse than controls on the inclusion task but not the exclusion task , misrecognizing different exemplars more often than healthy controls . -
pubmed
[ Resistance to
azithromycin of
Neisseria gonorrhoeae strains isolated in Poland in 2012 - 2013 years ] . -
pubmed
METHODS : Sixty five
Neisseria gonorrhoeae strains isolated from patients of the Department of Dermatology and Venereology in Warsaw in the second half of 2012 and first of 2013 were investigated . -
pubmed
CONCLUSIONS : The percentage of
azithromycin resistant
Neisseria gonorrhoeae strains is increasing in Poland and the antibiotic should not be used in monotherapy as
gonorrhoea patients . -
pubmed
Practical management of anticoagulation in
patients with
atrial fibrillation . -
pubmed
The attendees continued to work toward consensus on these topics , and present the key findings of this roundtable in a state - of- the - art review focusing on the practical aspects of anticoagulation care for the
patient with
atrial fibrillation . -
pubmed
Causative factors were
vulvar cancer in 14
patients , extramammary
Paget ' s disease in 2 ,
vulvar dysplasia in 5 , and combined vulvar and
vaginal cancer in 2 patients . -
pubmed
Xylene - induced
ear edema , carrageenan - induced paw
edema and
acetic acid - induced vascular permeability test were used to investigate the anti - inflammatory activities of GL in
mice . -
pubmed
BACKGROUND AND PURPOSE : Reducing body temperature can prolong tolerance to
ischemic injury such as
stroke or
myocardial infarction , but is difficult and uncomfortable in awake
patients because of
shivering . -
pubmed
RESULTS : All ten
subjects experienced
shivering on placebo days , with
shivering beginning at a mean ( SD ) temperature of 36.6 ( 0.3 ) C. The mean lowest temperature after placebo was 36.0 ( 0.3 ) C ( range 35.7 - 36.5 C ) . -
pubmed
CONCLUSION :
Dexmedetomidine decreases
shivering in normal
volunteers . -
pubmed
Intersphincteric anal lipofilling with micro - fragmented fat tissue for the treatment of
faecal incontinence : preliminary results of three
patients . -
pubmed
In February 2014 we treated 3
patients with
faecal incontinence . -
pubmed
Each
patient reported an improved Wexner
incontinence score at 1 month after the procedure . -
pubmed
MATERIAL AND METHODS : The study included 2049
patients undergoing transrectal ultrasound - guided 12 - core prostate biopsy used in the diagnosis of
prostate cancer . -
pubmed
To prevent development of
voiding disorders , the
patients also received oral alpha blockers for 30 days starting the day before the procedure . -
pubmed
Significance statement : Successful restoration of hearing in deaf
subjects by means of a cochlear implant requires a healthy spiral
ganglion cell population . -
pubmed
Nude mice are important in vivo model for characterization of cell
malignancy behavior ; however , many
cancer cells fail to form
tumors in it . -
pubmed
CONCLUSION : Collectively , these findings highlight the role of distinct adipose depots in
mice in the development of
obesity and emphasize the importance of selecting specific depots to study the effects of therapeutic interventions on adipose tissue function . -
pubmed
However , emerging evidence in
humans and
animal models suggests that dysregulated circuit function and gene expression across multiple brain regions drive
depressive phenotypes . -
pubmed
Monitoring of
Tumor Growth with
[ ( 18 ) F ]- FET PET in a
Mouse Model of
Glioblastoma : SUV Measurements and Volumetric Approaches . -
pubmed
This study investigates the potential of positron emission tomography ( PET ) using
O -( 2 -( 18 ) F - fluoroethyl )- L - tyrosine (
[ ( 18 ) F ]- FET ) to determine
tumor growth in a
murine glioblastoma (
GBM ) model - including estimation of the biological
tumor volume ( BTV ) , which has hitherto not been investigated in the pre - clinical context . -
pubmed
[ ( 18 ) F ]- FET PET with standard SUV measurements is feasible for
glioma imaging in the
GBM mouse model . -
pubmed
For the first time , we propose a histology - verified method allowing appropriate individual
BTV estimation for volumetric in vivo monitoring of
tumor growth with
[ ( 18 ) F ]- FET PET and show that standardized thresholds from routine clinical practice seem to be inappropriate for
BTV estimation in the
GBM mouse model . -
pubmed
Impact of Time to Appropriate Therapy on Mortality in Patients with
Vancomycin - Intermediate
Staphylococcus aureus Infection . -
pubmed
Despite the increasing incidence of
vancomycin - intermediate
Staphylococcus aureus ( VISA )
infections , few studies have examined the impact of delay in receipt of appropriate antimicrobial therapy on outcomes in
VISA patients . -
pubmed
Presence of a
VISA infection compared to that of a non - VISA
S. - pubmed
Future studies should ( i ) include larger numbers of patients with VISA
infections to confirm the findings presented here and ( ii ) determine the optimal antibiotic therapy for
critically ill patients with
MRSA and
VISA infections . -
pubmed
METHODS : Adults and children admitted to Chittagong Medical College Hospital with a temperature of & gt;=38.0 C were investigated using a blood smear for
malaria , a blood culture , real - time PCR to detect
Salmonella Typhi ,
S. - pubmed
RESULTS : We enrolled 300 febrile
patients with a negative
malaria smear between January and June 2012 : 156
children ( aged & lt;=15 years ) and 144 adults with a median ( interquartile range ) age of 13 ( 5 - 31 ) years and median ( IQR ) illness duration before admission of five ( 2 - 8) days . -
pubmed
Clinical
enteric fever was diagnosed in 52
patients ( 17.3 % ) , lower
respiratory tract infection in 48 ( 16.0 % ) , non - specific
febrile illness in 48 ( 16.0 % ) , a
CNS infection in 37 patients ( 12.3 % ) ,
urinary sepsis in 23 patients ( 7.7 % ) , an
upper respiratory tract infection in 21 patients ( 7.0 % ) , and
diarrhea or
dysentery in 21 patients ( 7.0 % ) . -
pubmed
Excessive Cytosolic DNA Fragments as a Potential Trigger of
Graves ' Disease : An Encrypted Message Sent by
Animal Models . -
pubmed
Three - dimensional micro computed tomography analysis of the lung vasculature and differential adipose proteomics in the Sugen /
hypoxia rat model of
pulmonary arterial hypertension . -
pubmed
This study used novel micro computed tomography ( microCT ) three - dimensional modeling to investigate the degree of remodeling of the lung vasculature and differential proteomics to determine small
visceral adipose dysfunction in
rats with severe
PAH . -
pubmed
An increased rate of
dysphonia was observed among
patients undergoing revision surgery ( 25.0 % ) compared to primary surgery ( 1.6 % ) , but stratification by number of levels , gender , and smoking status yielded no differences in complication rates . -
pubmed
Assessment of the effects of switching oral
bisphosphonates to
denosumab or daily
teriparatide in
patients with
rheumatoid arthritis . -
pubmed
The aim of this observational , non - randomized study was to clarify the unknown effects of switching oral
bisphosphonates ( BPs ) to denosumab ( DMAb ) or daily
teriparatide (
TPTD ) in
patients with
rheumatoid arthritis (
RA ) . -
pubmed
Participants preferred
HIV oral testing because it was :
pain free ( 91 % , n = 399 ) and did not require blood draw ( 82 % , n = 360 ) . -
pubmed
Here , we explore pollinator preferences and the genetic architecture of floral divergence using an extensive genetic mapping study in the hybrid zone of two
Ipomopsis aggregata subspecies that exhibit a hummingbird and a hawkmoth pollinator
syndrome . -
pubmed
We included 206 pregnant
women with
endometriosis : 148 ( 71.8 % ) with
endometriosis only , 38 ( 18.4 % ) with focal
adenomyosis and 20 ( 9.7 % ) with diffuse
adenomyosis . -
pubmed
Quantitative monitoring for residual
paralysis is advocated as part of routine monitoring with the use of NMBDs for improved
patient safety . -
pubmed
In the last decade ,
seizure prediction systems have gained a lot of attention because of their enormous potential to largely improve the quality - of - life of the
epileptic patients . -
pubmed
Comprehensive epidemiological surveys for
Lyme disease have not been conducted for the Bactrian
camel in China . -
pubmed
Two Borrelia species that cause
Lyme disease and one that causes
relapsing fever were identified in the
camel blood samples by sequencing . -
pubmed
The findings of this study indicate that the
Bactrian camel may serve as a potential natural host of
Lyme disease and/or
relapsing fever in China . -
pubmed
Predictive value of microRNA let-7a expression for efficacy and prognosis of radiotherapy in
patients with
lung cancer brain
metastasis : A case - control study . -
pubmed
This study aims to investigate the value of serum microRNA - let-7a ( miR - let-7a ) expression in predicting efficacy and prognosis of radiotherapy in
patients with
lung cancer brain
metastasis . -
pubmed
Later , we found that decreased miR - let-7a displayed an unfavorable role in radiotherapy efficacy and overall survival rate of
patients with
lung cancer brain metastasis . -
pubmed
BACKGROUND : Endotracheal intubation can occur in up to 60 % of
critically ill patients . -
pubmed
METHODS : A multicenter , observational , prospective study of adult
critically ill patients admitted to both medical and surgical intensive care units ( ICUs ) was conducted . -
pubmed
A 20 - year - old
man submitted to surgical insertion of a lumboperitoneal drain as a treatment for
intracranial hypertension , secondary to
venous sinus thrombosis , developed severe
headache accompanied by
nausea ,
vomiting , and
diplopia 24 hours postoperative . -
pubmed
Pain relief was immediate , complete , and sustained for about 24 hours ; a second block was performed effectively with
pain control , and the
patient was discharged . -
pubmed
PURPOSE :
Venous thromboembolism (
VTE ) is the second most common cause of
death in hospitalized
patients with
cancer , and
cancer treatments may exacerbate
VTE risk . -
pubmed
After carefully compensating spatially dependent dispersion , we achieve delineation of fine outer retinal bands in
mouse strains of varying pigmentation . -
pubmed
Since 1997 , a
yellowing disease has been observed in greenhouse
tomato (
Lycopersicon escu - lentum ) . -
pubmed
OBJECTIVE : Complete surgical resection of metastatic sites has been shown to prolong survival in select
patients with oligometastatic
RCC . -
pubmed
The objective of this study was to explore the utility of PSMA - targeted
18F - DCFPyL PET / CT in
patients with presumed oligometastatic
clear cell RCC . -
pubmed
In the present analysis ,
patients with oligometastatic clear cell
RCC , defined as & lt;= 3 metastatic lesions on conventional imaging , were evaluated . -
pubmed
RESULTS : The final cohort included 14
patients with oligometastatic
clear cell RCC . -
pubmed
Risk Factors for Major Adverse Cardiovascular Events in Phase III and Long - Term Extension Studies of
Tofacitinib in
Patients With
Rheumatoid Arthritis . -
pubmed
This study was undertaken to evaluate the risk of major adverse cardiovascular events ( MACE ) in
patients with
RA receiving
tofacitinib . -
pubmed
METHODS : Data were pooled from
patients with moderately to severely active
RA receiving & gt;=1
tofacitinib dose in 6 phase III and 2 long - term extension studies over 7 years . -
pubmed
RESULTS : Fifty - two
MACE occurred in 4,076
patients over 12,873
patient - years of exposure ( incidence rate 0.4
patients with events per 100 patient - years ) . -
pubmed
Galloyl - Hexahydroxydiphenoyl ( HHDP )- Glucose Isolated From
Punica granatum L. Leaves Protects Against Lipopolysaccharide ( LPS)-Induced
Acute Lung Injury in BALB / c
Mice . -
pubmed
In this study , we investigated the therapeutic effects of
galloyl - hexahydroxydiphenoyl ( HHDP )- glucose isolated from
pomegranate leaves on lipopolysaccharide ( LPS)-induced
acute lung injury (
ALI ) in
mice . -
pubmed
In addition , the
ALI mice treated with
galloyl - HHDP - glucose also presented reduced lung inflammatory cell accumulation , especially that of neutrophils , in their BALF and lungs . -
pubmed
Effect of verbal and written information on
pain perception in
patients undergoing fixed orthodontic treatment : a randomized controlled trial . -
pubmed
BACKGROUND :
Pain can discourage
patients from seeking orthodontic treatment or compromise their compliance during therapy . -
pubmed
Thirty - eight
patients with
AIS undergoing Cheneau - type bracing were included . -
pubmed
Furthermore , investigation on the mechanisms underpinning the morphological and behavioral traits associated with canid domestication
syndrome is of significance not only for scientific study but also for
human medical research . -
pubmed
Comparative Pro - cognitive and Neurochemical Profiles of
Glycine Modulatory Site Agonists and
Glycine Reuptake Inhibitors in the
Rat : Potential Relevance to
Cognitive Dysfunction and Its Management . -
pubmed
and
D - cycloserine ( 2.5 - 40 mg / kg ) that all dose - dependently prevented
scopolamine disruption of social recognition in adult
rats . -
pubmed
Finally , in
rats socially isolated from weaning ( a neurodevelopmental model of
schizophrenia ) ,
S18841 ( 2.5 and 10 mg / kg s.c . ) -
pubmed
In conclusion , despite contrasting neurochemical profiles , partial
glycine site agonists and
glycine reuptake inhibitors exhibit comparable pro - cognitive effects in
rats of potential relevance to treatment of
schizophrenia and other
brain disorders where cognitive performance is impaired . -
pubmed
Diversity of bacteriophages encoding
Panton - Valentine leukocidin in temporally and geographically related
Staphylococcus aureus . -
pubmed
aureus strains that cause serious
infections and clones of community - associated
methicillin - resistant
S. - pubmed
Methods : A retrospective analysis was conducted on the clinical data of 16
patients with the low distal humerus
fracture between January 2016 and January 2018 at Department of Orthopaedics , Shanghai Tongji Hospital Affiliated to Tongji University . -
pubmed
Conclusion : Laparoscopic rectopexy is a safe minimally invasive approach for
children with idiopathic
RP that offers high
patient satisfaction with same - day discharge , early recovery , and low
recurrence . -
pubmed
Estimating
daytime sleepiness with previous night EEG , EOG and EMG spectrograms in
patients with suspected
sleep apnea using a convolutional neural network . -
pubmed
We trained a convolutional neural network ( CNN ) classifier using electroencephalography , electrooculography , and chin electromyography signals from 2014
patients with suspected
OSA . -
pubmed
The CNN was trained to classify the
patients into four
sleepiness categories based on their mean sleep latency ( MSL ) ; severe ( MSL<5min ) , moderate ( 5<=MSL<10 ) , mild ( 10<=MSL<15 ) and normal ( MSL>=15 ) . -
pubmed
Results : A convenience sample of 74
children , aged 9 - 68 months ( mean : 32.45 , SD : 14.08 ) with
mobility limitations , and their parents participated . -
pubmed
In the present study , we investigated the protective effects of
piperine against
mastitis using a
mouse mastitis model . -
pubmed
Procoagulant Disorders in
Patients with Newly Diagnosed
Pancreatic Adenocarcinoma . -
pubmed
Analyzed
patients were hospitalized in the Department of
Digestive Tract Diseases , Medical University of Lodz or in the Department of Digestive Tract Surgery , Silesian University , Katowice , Poland . -
pubmed
Conclusions : The
coagulation disorders are present in the majority of
patients with
pancreatic adenocarcinoma already at the diagnosis stage and reflect
cancer progression and spread . -
pubmed
METHODS : 90
patients with acute uncomplicated
appendicitis who underwent emergency open appendectomy from December 2017 to August 2018 were included in this prospective study . -
pubmed
Results : Perceived accuracy of health misinformation was strongly correlated across statins ,
cancer , and the
HPV vaccine ( rs > = .70 ) , indicating that individuals who are susceptible to misinformation about one of these topics are very likely to believe misinformation about the other topics as well . -
pubmed
The effects of
pyridostigmine pretreatment on the
neuromuscular blockade produced by soman in anaesthetized , atropinized
animals have been studied on the soleus and anterior tibialis muscle (
rhesus monkeys ,
cats and
rabbits ) and the gastrocnemius muscle ( guinea - pigs and
rats ) . -
pubmed
A new test showing abnormal net
Na+ and
K + fluxes in erythrocytes of essential
hypertensive patients . -
pubmed
A new and simple laboratory test for measuring net
Na + and
K + fluxes in
Na +-loaded /
K +-depleted
human erythrocytes was developed and applied to
hypertension . -
pubmed
The ratio of
Na+/K+ net fluxes was therefore reduced in all essential
hypertensive patients . -
pubmed
Conversely ,
Na + and K+ erythrocyte fluxes were normal in
hypertension of renal origin ( 5
patients ) . -
pubmed
[ Ambulatory rehabilitation of
myocardial infarct patients . -
pubmed
Streptococcus faecalis , while the most common streptococcal serotype causing
urinary tract infection , is not the only one . -
pubmed
Reduction of
hypoxic pulmonary vasoconstriction during
diethyl ether anaesthesia in the
dog . -
pubmed
Corticosteroid production by the
human foetus : evidence from analysis of urine from
women pregnant with a normal or an
anencephalic foetus . -
pubmed
We performed MR studies of 16
patients with
head and neck tumors with detailed clinical , surgical , and pathologic information . -
pubmed
The data indicated that the function of T helper cells in
patients with
TB was impaired , and the impairment was more serious in the
patients with longer illness . -
pubmed
Energy expenditure and substrate oxidation in
patients with
cirrhosis : the impact of cause , clinical staging and nutritional state . -
pubmed
This article is about resting energy expenditure and substrate oxidation rates in 123
patients with biopsy - proven
cirrhosis differing with respect to cause , duration of the disease , biochemical parameters of parenchymal cell damage ,
cholestasis , liver function , number of complications , clinical staging and nutritional state . -
pubmed
Lipid oxidation was increased , but
glucose oxidation was reduced in nearly all
patients with
cirrhosis . -
pubmed
It may cause
malnutrition and contributes to the clinical outcome of
patients with
chronic liver disease . -
pubmed
The eight
patients were selected because they had low anticapsular antibody responses to
Hib disease . -
pubmed
Only one of the eight
children had a history of previous severe , recurrent
infections . -
pubmed
A case of
Bence Jones kappa multiple myeloma with
meningeal involvement in a 64 - year - old
woman is presented . -
pubmed
Exertional headaches in
patients with
Arnold - Chiari malformation (
ACM ) are well described . -
pubmed
We report four
patients with
Type I ACM and recurrent
headaches . -
pubmed
These
patients presented , respectively , with low spinal fluid pressure
headache ,
migraine without aura ,
migraine with aura , and
migraine with
prolonged aura . -
pubmed
This report suggests the need for observing
patients with recurrent
headaches for any physical stigmata of
craniovertebral junction anomalies , and the need to exclude
ACM in such patients . -
pubmed
Fifty - six
patients with traumatic and 117
patients with
inflammatory lesions of the knee and ankle were examined with a 2 T ( 69 examinations ) or 0.23 T ( 104 examinations ) MR system . -
pubmed
In
patients with traumatic and
inflammatory diseases of the knee and ankle , high field imaging at 2 T provided better image quality than low field imaging at 0.23 T. -
pubmed
A retrospective study was done on 30
patients who underwent surgical correction of the
penile deformity secondary to
Peyronie ' s disease between 1983 and 1988 . -
pubmed
Over - all , 19
patients ( 63 % ) improved postoperatively , which implied erection free of
pain with minimal or no
deformity and the ability to perform normal sexual intercourse . -
pubmed
We recommend this procedure for
patients in whom surgical correction of the
deformity is indicated . -
pubmed
Additionally , response following
ifosfamide treatment is being evaluated for previously untreated
children with
osteosarcoma and
rhabdomyosarcoma after 6 weeks of treatment , and for previously untreated
patients with
Ewing ' s sarcoma after 9 weeks of treatment with
ifosfamide /
VP-16 (
etoposide ) given in combination . -
pubmed
Treatment of
depressed tinnitus patients with
nortriptyline . -
pubmed
Patients disabled by
tinnitus show a high prevalence of
major depression . -
pubmed
To explore further this link between
tinnitus and
depression , and to investigate the efficacy of treating
depression in the treatment of
tinnitus , a single - blind , placebo - washout , nonrandomized pilot study of the tricyclic antidepressant
nortriptyline (
hydrochloride ) was undertaken in disabled
tinnitus patients who also met diagnostic criteria for
major depression . -
pubmed
Sodium sensitivity in normotensive and borderline
hypertensive humans . -
pubmed
The responses to
sodium depletion and repletion were studied in subgroups of 92 normotensive and 65 borderline
hypertensive individuals . -
pubmed
Maternal - paternal
toxicity (
body weight evolution , feather coat ) and tolerance in newborn
pigeons ( general behaviour , daily gain in
body weight , feathering ,
skeletal anomalies ) were also evaluated . -
pubmed
Hatched
pigeons showed a satisfactory daily
weight gain and
deaths among these birds were exceptional . -
pubmed
A potential
animal model for
autoimmune reproductive failure . -
pubmed
Eighty - eight
patients have been successfully treated endoscopically without complications using contact
neodymium yttrium aluminum garnet : (
YAG ) laser probes ( endoprobes ) for
tumors and
bleeding and during open surgery ( laser scalpel ) to perform hepatic and pancreatic resections . -
pubmed
Two hundred seventy ( 270 ) consecutive surgical
patients treated at Roswell Park Memorial Institute for
carcinoma of the oral cavity , oropharynx , hypopharynx , and larynx between 1977 and 1982 were reviewed to determine the relationship between pathological findings at the
surgical margins of the primary
tumor and the incidence of local
recurrence and clinical outcome . -
pubmed
The estimated 5 - year disease - free survival rate was 39 % for
patients with free
surgical margins ( 10%--hypopharynx , 30%--oropharynx , 40%--oral cavity , and 53%--larynx ) and 7 % for not - free
surgical margins . -
pubmed
Patients with free
surgical margins and with well - differentiated
squamous cell carcinoma had better prognosis than those
patients with moderately- and poorly - differentiated
carcinomas . -
pubmed
The extent of stress - protection was investigated in 12
patients with previous
tibial fractures treated by steel plate fixation . -
pubmed
Subgaleal
hematoma in a
child , without
skull fracture . -
pubmed
[
ATP and
2,3 - DPG concentrations in the erythrocytes of
peritonitis patients ] . -
pubmed
[ Independence of
neurogenic atrophy and
alloxan diabetic atrophy in their effects on the transport of
phosphate ion in the gastronemus of the
rat ] . -
pubmed
We speculate that the somewhat surprising similarity between the ecology of the
mouse large intestine and that of a
CF culture in a glass vessel is due to the fact that both are dominated by thick layers of complex bacterial flora , the composition of which is controlled by their metabolic activities and by their relative ability to adhere to each other . -
pubmed
Although
patients with
bronchiolitis elicited similar levels of the activity until the first week , the response was significantly suppressed during the subsequent two weeks . -
pubmed
The response at the second week in this group was significantly lower than those of corresponding specimens obtained from
patients with
pneumonia ( p less than 0.01 ) or
tracheobronchitis ( p less than 0.05 ) , suggesting a close association of the responsiveness with underlying mechanisms of
bronchiolitis induced by
RSV . -
pubmed
Chronic experiments on
cats were carried out to study the effect of
haloperidol and
clozapine on the pattern of
contralateral rotations produced by electric stimulation of the caudate nucleus . -
pubmed
Malignancy and anchorage independence of
Djungarian hamster tumor cell lines resistant to different doses ( 0.1 - 5.0 micrograms / ml ) of
colchicine were studied . -
pubmed
Variation of the
arteria profunda femoris in
man . -
pubmed
Signs of
peritoneal irritation were present in all patients , including the 16
children receiving
corticosteroid therapy . -
pubmed
There is weak evidence that SPECT is useful in : ( a ) detecting
pseudarthroses after failed spinal fusion , ( b ) evaluating young
patients with
back pain and ( c ) distinguishing benign from
malignant lesions in
cancer patients . -
pubmed
CONCLUSION : The decision to use SPECT in most
patients with
low back pain can not be supported by clinical trials . -
pubmed
Similarly , five - year disease - free survival in 17
patients with Dukes B and C
cancers who had curative resections did not differ between the groups ( log rank test : chi - squared = 0.08 ; P & gt ; 0.25 ) . -
pubmed
To ascertain the clinical value in
gynecologic cancers , the authors studied 612 nonpregnant
women . -
pubmed
Thus , gamma 2b H chains : 1 ) can act alone to promote the development of mature B cells , 2 ) synergize with microH chains for allelic exclusion , and 3 ) vary in their influence on B cell development in different transgenic
mouse strains . -
pubmed
The safety study primarily demonstrated
drowsiness in one - fourth of the
patients receiving placebo and active treatment . -
pubmed
Protection against
alloxan - induced
diabetes by
diethyldithiocarbamate and
disulfiram in
mice . -
pubmed
Fasted
mice did not exhibit
hyperglycemia at 0.5 hr after
DEDC injection , and
alloxan given at that time produced
diabetes . -
pubmed
These findings indicate that
DEDC itself protected
mice from
alloxan - induced
diabetes by the indirect mechanism of producing
hyperglycemia at the time of
alloxan administration . -
pubmed
The anti - diabetogenic action of low doses of
DS and
DEDC , in
animals lacking
hyperglycemia at the time of
alloxan injection , is likely based on a mechanism other than one involving
hyperglycemia . -
pubmed
The ease of isolation , growth , and transfection of primary
mouse myoblasts under the conditions described here expand the opportunities to study muscle cell growth and differentiation using myoblasts from normal as well as mutant
strains of
mice . -
pubmed
The properties of these cells after transplantation -- the stability of resulting hybrid myofibers without immune suppression , the persistence of transgene expression , and the lack of tumorigenicity -- suggest that studies of cell - mediated gene therapy using primary myoblasts can now be broadly applied to
mouse models of
human muscle and non - muscle diseases . -
pubmed
Characterization of twenty - six new heat
shock genes of
Escherichia coli . -
pubmed
Here we report the characterization of 26 new heat
shock genes of
E. - pubmed
A 63 - year - old
man with multiple nodules and pathological findings of
acantholysis is reported as a case of warty
dyskeratoma presenting with multiple lesions . -
pubmed
The binding activity of 2 of the
CDDP - damage - recognition proteins , of relative molecular mass 48 and 97 kDa , is greater in a
CDDP - resistant
human ovarian tumour cell line than in the parental sensitive line . -
pubmed
The relation between left - ventricular
stroke volume ( SV ) and end - diastolic volume ( EDV ) was determined based on angiocardiographic measurements in 10 open - chest
minipigs under varying filling conditions ( blood letting or infusions ) . -
pubmed
Twenty three
patients suffered from
renal vasculitis , most commonly
Wegener ' s granulomatosis ( 14
patients ) and microscopic
polyarthritis ( 7
patients ) . -
pubmed
IgA nephropathy ( 7
patients ) and
idiopathic necrotizing / crescentic glomerulonephritis ( 8
patients ) prevailed in
patients with limited
renal involvement . -
pubmed
Renal morphology and function was most seriously impaired in
patients with
Wegener ' s granulomatosis . -
pubmed
Clinical signs of extrarenal involvement are present in about 50 % of
patients with ANCA - positive
glomerulonephritis . -
pubmed
IMPLICATIONS FOR NURSING PRACTICE : Nurses can play a major role in the supportive care of
patients with
anemia through interventions related to pharmacological therapy , blood transfusions , nutritional counseling , and symptom management . -
pubmed
BACKGROUND : The addition of
droperidol to
morphine for
patient - controlled analgesia reduces the incidence of
nausea and
vomiting , but may result in unwanted side effects . -
pubmed
Subjective
drowsiness which resulted in withdrawal from the study occurred in two
patients , both of whom were receiving
droperidol , and though all
patients who completed the study were satisfied with their analgesia overall , significantly more of those receiving unsupplemented
morphine ( 11/19 compared with 4/18 , P & lt ; 0.05 ) described it as excellent . -
pubmed
Injection of zymosan - activated plasma into the
rat paw induced
oedema formation . -
pubmed
A new
heart failure model in
rat by an end - to - side femoral vessel anastomosis . -
pubmed
OBJECTIVE : The aim of this study was to develop a new shunting procedure for producing
heart failure in the
rat incorporating microvascular techniques and avoiding an abdominal operation . -
pubmed
CONCLUSION : This model provides a relatively simple and reproducible means of creating high output
heart failure and
cardiac hypertrophy in the
rat without necessitating abdominal surgery . -
pubmed
METHODS AND RESULTS : We recorded peroneal muscle sympathetic nerve activity in 17 treated
heart failure patients ( 16 men,1
woman ; mean ejection fraction of 26 . -
pubmed
The role of the ixodid tick
Hyalomma lusitanicum Koch 1844 as a vector of Mediterranean or
tropical theileriosis ( caused by the protozoan parasite
Theileria annulata Dschunkowsky et Luhs 1904 ) in southern Spain was studied . -
pubmed
annulata - infected
cattle from the
theileriosis enzootic area studied ( province of Cadiz , southern Spain ) . -
pubmed
Likewise , we found that all sera of the
cattle previously considered as suspected of
theileriosis by clinical signs , tested for
T. - pubmed
annulata - infected
cattle in this enzootic area and fed on an uninfected calf in an experimental farm free of
theileriosis and ticks . -
pubmed
Five per cent of
patients with
germ cell tumours of the testis will develop a further
tumour in the contralateral testis . -
pubmed
Efficacy of implantable cardioverter - defibrillators for the prevention of
sudden death in
patients with
hypertrophic cardiomyopathy . -
pubmed
BACKGROUND :
Hypertrophic cardiomyopathy is a
genetic disease associated with a risk of
ventricular tachyarrhythmias and
sudden death , especially in young
patients . -
pubmed
METHODS : We conducted a retrospective multicenter study of the efficacy of implantable cardioverter - defibrillators in preventing
sudden death in 128
patients with
hypertrophic cardiomyopathy who were judged to be at high risk for
sudden death . -
pubmed
In the group of 43
patients who received defibrillators for secondary prevention ( after
cardiac arrest or sustained
ventricular tachycardia ) , the devices were activated appropriately in 19
patients ( 11 percent per year ) . -
pubmed
In all 21
patients with stored electrographic data and appropriate interventions , the interventions were triggered by
ventricular tachycardia or fibrillation . -
pubmed
CONCLUSIONS :
Ventricular tachycardia or fibrillation appears to be the principal mechanism of
sudden death in
patients with
hypertrophic cardiomyopathy . -
pubmed
In high - risk
patients with
hypertrophic cardiomyopathy , implantable defibrillators are highly effective in terminating such
arrhythmias , indicating that these devices have a role in the primary and secondary prevention of
sudden death . -
pubmed
Enteropathy - type intestinal T - cell lymphoma : clinical features and treatment of 31
patients in a single center . -
pubmed
PURPOSE : We report the clinical features and treatment of 31
patients with a diagnosis of
enteropathy - type intestinal T - cell lymphoma treated at the Wessex Regional Medical Oncology Unit in Southampton between 1979 and 1996 ( 23 men , eight
women ) . -
pubmed
PATIENTS AND METHODS :
Patients were identified from our
lymphoma database . -
pubmed
RESULTS : Twelve
patients ( 35 % ) had a documented clinical history of adult - onset
celiac disease , and a further three had histologic features consistent with
celiac disease in resected areas of the small bowel not infiltrated with
lymphoma . -
pubmed
Infection of Bergmann glia in the cerebellum of a
skunk experimentally infected with street
rabies virus . -
pubmed
Rabies virus is a highly neuronotropic virus and
glial cell infection is not prominent in the central nervous system ( CNS ) . -
pubmed
Paraffin - embedded tissues from the cerebella of skunks experimentally infected with either a
skunk salivary gland isolate of
street rabies virus or the challenge virus standard ( CVS )
strain of fixed
rabies virus were examined with immunoperoxidase staining for
rabies virus antigen by using an anti -
rabies virus nucleocapsid protein monoclonal antibody . -
pubmed
A skunk infected with street
rabies virus showed prominent
infection of Bergmann glia . -
pubmed
These findings indicate that although
rabies virus is a highly neuronotropic virus , street
rabies virus
strains do not always demonstrate strict neuronotropism in the central nervous system . -
pubmed
The
patients suffered from
stenoses ( n = 6 ) , occlusions ( n = 7 ) ,
aneurysms , ( n = 2 ) or acute
hemorrhage ( n = 2 ) . -
pubmed
In 4
Patients of the
stenosis - group re -
stenosis occurred and following stent - implantation one occlusion after 6 months was observed . -
pubmed
Exposure to ionizing radiation in
children undergoing Amplatzer device placement to close
atrial septal defects . -
pubmed
Between June 1998 and April 1999 , dosimetry was carried out on 12
patients with Amplatzer device occlusion of
atrial septal defects ( n = 10 ) or Fontan fenestration ( n =) and 12 age - matched
patients who underwent diagnostic catherization . -
pubmed
Dietary restriction ( DR ) increases the lifespan of
rodents and increases their resistance to several different age - related diseases including
cancer and
diabetes . -
pubmed
OBJECTIVE : To evaluate the effects of mechanical compression of the brain - stem in
patients with
vertebrobasilar dolichoectasia (
VBD ) . -
pubmed
METHODS : In the framework of a prospective , observational study that collected clinical and laboratory data in
patients with
VBD , we studied 20
patients with compression of the brain - stem due to ectatic , tortuous basilar or vertebral arteries . -
pubmed
Patients with
cerebral lesions other than small lacunae in the white matter of the cerebral hemispheres were excluded from the study . -
pubmed
RESULTS : Almost all of the
patients complained of
auditory or vestibular symptoms and none had symptoms or signs of
impairment of long tracts or the facial and trigeminal nerves . -
pubmed
Functional investigations may be useful in the long - term management of these
patients , since
VBD may be progressive and surgical correction may be required at some stage . -
pubmed
To define genes associated with the
pigmentary disorder vitiligo , gene expression was compared in non - lesional melanocytes cultured from three
vitiligo patients and from three control melanocyte cultures by differential display . -
pubmed
RNH-6270 did not affect serum - stimulated DNA synthesis in VSMCs from both
rat strains . -
pubmed
RNH-6270 abolished
angiotensin II - stimulated DNA synthesis in VSMC from both
rat strains . -
pubmed
OBJECTIVE : Using three - dimensional computed tomography , we investigated the morphologic
deformity of the birth canal in
patients with
developmental dysplasia of the hip who underwent dome pelvic osteotomy . -
pubmed
STUDY DESIGN : Thirty - five normal
subjects , 34
patients with
developmental dysplasia of the hip who did not undergo dome pelvic osteotomy , and 21
patients with
developmental dysplasia of the hip who underwent dome pelvic osteotomy were recruited for the study . -
pubmed
CONCLUSION : Anthropoid - type pelvis ( a long pelvic inlet diameter in the sagittal dimension while the corresponding measurement in the transverse dimension is short ) was observed in as many as 90.5 % of
patients with
developmental dysplasia of the hip after dome pelvic osteotomy . -
pubmed
MATERIALS AND METHODS : Seven healthy adult
volunteers with no history of
neurologic disease or
head trauma were recruited and gave their informed consent . -
pubmed
Mechanisms of
ocular toxicity using the in vitro
bovine lens and
sodium dodecyl sulfate as a chemical model . -
pubmed
Although parasite clearance times were shorter in the
quinine -
rifampin - treated
patients ( mean + /- standard deviation , 70 + /- 21 versus 82 + /- 18 h ; P = 0.023 ) ,
recrudescence rates were five times higher ( n = 15 of 23 ; 65 % ) than those obtained with
quinine alone ( n = 3 of 25 ; 12 % ) , P & lt ; 0.001 . -
pubmed
Rifampin should not be combined with
quinine for the treatment of
malaria , and the doses of
quinine should probably be increased in
patients who are already receiving
rifampin treatment . -
pubmed
The carotid IMT was measured by B - mode ultrasonography in
type 2 diabetic patients . -
pubmed
Acetate metabolism in isolated epididymal adipost tissue from
obese -
hyperglycemic mice of different ages . -
pubmed
Influence of
p - hydroxy - propiophenone on
liver tumorigenesis in
rats ingesting
ethionine and
N-2 - fluorenylacetamide . -
pubmed
[
Ascites and reversible experimental
edema in
dogs researches on the role of nutrition , portal pressure and antidiuretic factors ] . -
pubmed
OBJECTIVE : The purpose of this study was to establish selection criteria for intentional limited resection in
patients with
peripheral lung cancer . -
pubmed
RESULTS : The positive rate of invasive factors was 30.8 % among the
patients with
tumors 2 cm or less in diameter , and significantly lower than the 44.0 % noted in those whose
tumor diameter was in the 2.1 - 3.0 cm range . -
pubmed
The positive rate was significantly lower in 90
patients with type A or B
adenocarcinoma , and none of these
patients developed postoperative
recurrence . -
pubmed
In 24 of these 90
patients , the
tumor diameter was in the 2.1 - 3.0 cm range . -
pubmed
The 5 - year survival rate in the 74
patients with pT1N0M0 and
tumors 2 cm or less in diameter who underwent limited resection was 89.1 % . -
pubmed
Anti - inflammatory effect of
methoxyphenamine compound in
rat model of
chronic obstructive pulmonary disease . -
pubmed
METHODS : Adult
rat model of
COPD (
COPD group ) was induced by intratracheal instillation of lipopolysaccharides and exposure to cigarette smoke . -
pubmed
CONCLUSION : MC has anti - inflammmatory effect in the
rats with
COPD . -
pubmed
STUDY OBJECTIVES : Recently , we demonstrated significantly improved baroreflex sensitivity ( BRS ) and autonomic balance after 31 % supplemental
oxygen ( SuppO2 ) in resting
patients with
chronic obstructive pulmonary disease (
COPD ) . -
pubmed
PARTICIPANTS : Seventy
subjects with moderate to severe
COPD . -
pubmed
BRS was derived using the sequence method before and after treatments with compressed air ( CA ) and 30 % SuppO2 in 70
individuals with
COPD via a counterbalanced crossover design . -
pubmed
Cerebral edema is the primary cause of morbidity and mortality in
children and
adolescents with
diabetic ketoacidosis (
DKA ) . -
pubmed
We report a case of an adolescent
female with life - threatening
DKA - related
cerebral edema who responded to a combination of
mannitol and hypertonic saline . -
pubmed
In some
animals the liver was sampled and showed periportal
fibrosis , bile duct proliferation and sometimes
necrosis . -
pubmed
METHODS AND RESULTS : A retrospective observational study of 126
patients with a
ST - segment elevation myocardial infarction (
STEMI ) ; 101
patients had reperfusion therapy ( 93 thrombolysis , 8 PTCA ) . -
pubmed
This article summarizes our current understanding of
ischemic heart disease and
heart failure in
patients with
diabetes mellitus , highlighting gaps in our knowledge about the relationship between
diabetes and
cardiovascular disease . -
pubmed
MATERIAL AND METHODS : We performed a metaanalysis to combine the results of the studies which compared the frequency of
depression in
MS patients with the prevalence in patients with other
chronic diseases . -
pubmed
Treatment of
stroke in adult
mice with
atorvastatin daily for 14 days , starting at 24 hours after
MCAO , shows significant improvement in functional recovery compared with control
animals . -
pubmed
The medical records of
patients with high - grade
osteosarcoma observed at the authors ' institution between 1972 and 1999 were reviewed to study whether
osteosarcoma in preadolescent patients has a different biology and a worse prognosis than in older patients . -
pubmed
In the second analysis , only 1,136
patients ( 317 preadolescent and 819 older
patients ) with
nonmetastatic extremity osteosarcoma , treated with the same protocols of chemotherapy , were evaluated to assess differences in prognosis and in the pattern of
relapse . -
pubmed
Most
preadolescents were female ( 56 % vs. 44 % , P & lt ; 0.0001 ) , and most
tumors were located in the extremity ( 95 % vs. 5 % , P & lt ; 0.001 ) . -
pubmed
To compare the systemic oxidant - antioxidant status in
patients with acute exacerbations and stable
asthma , we measured a wide range of parameters of oxidant - antioxidant balance in leukocytes , plasma , and red cells of 32
patients with acute exacerbations and 97
patients with stable
asthma . -
pubmed
For
patients with advanced
non - small cell lung cancer (
NSCLC ) , chemotherapy , alone or in combination with radiation therapy , is considered the standard treatment . -
pubmed
Goals of molecular targeted therapy studies include the following : better understanding of the exact role of particular growth factors in specific
tumors ; establishment of new clinical study designs for biological agents ; and tailoring appropriate combinations of conventional chemotherapy and/or radiotherapy with biological therapy for specific
patients . -
pubmed
Achievement of these goals will hopefully lead to incorporation of biological therapy into the current anticancer arsenal , for the benefit of
lung cancer patients . -
pubmed
The promoter and reporter were co - transfected into a
human prostate cancer cell line
PC3 - M with the aid of Lipofectamin 2000 . -
pubmed
The
Vibrio cholerae bacterium causes devastating
diarrhea when it infects the
human intestine . -
pubmed
In 1986 - 2003 yrs the interventions for
cancer of the operated stomach were performed in 32
patients . -
pubmed
Evaluation of diagnostic tests and
argatroban or
lepirudin therapy in
patients with suspected
heparin - induced
thrombocytopenia . -
pubmed
STUDY OBJECTIVES : To evaluate diagnostic tests for
heparin - induced
thrombocytopenia (
HIT ) , a serious drug reaction that can occur in
patients receiving
heparin , and to evaluate treatment with
direct thrombin inhibitors - the only initial drug therapy that decreases the risk of
thromboembolism associated with immune - mediated
HIT . -
pubmed
SUBJECTS :
Patients with
HIT treated with
argatroban or
lepirudin between January 1 , 2000 , and December 31 , 2003 . -
pubmed
MEASUREMENTS AND MAIN RESULTS :
Patients were assessed for dosage and duration of
argatroban or
lepirudin therapy ,
HIT diagnostic tests , and clinically significant adverse events . -
pubmed
Although
platelet - aggregation tests were ordered in 55 ( 72 % ) of 76
patients , they were not useful in 16 ( 29 % ) because of equivocal or contradictory results . -
pubmed
OBJECT :
Adenovirus vector (
AdV)-mediated gene delivery has been recently demonstrated in clinical trials as a novel potential treatment for
malignant gliomas . -
pubmed
Severe
liver injury after initiating therapy with
atomoxetine in two
children . -
pubmed
Two
children presented with acute
hepatitis after starting therapy with
atomoxetine (
Strattera ) . -
pubmed
In one
child , no competing diagnosis could be identified , and
liver injury resolved completely on withdrawal of the medication . -
pubmed
In the second
child , the evaluation was suggestive of
type 1 autoimmune hepatitis ; she subsequently improved with removal of
atomoxetine and concomitant immunosuppressive therapy . -
pubmed
METHODS : The weight changes of 228
children with
obesity were evaluated according to frequency of child and parental self - monitoring . -
pubmed
Long - term high - fat diet induces
pancreatic injuries via pancreatic microcirculatory disturbances and oxidative stress in
rats with
hyperlipidemia . -
pubmed
The objective of this study was to induce
hyperlipidemia in
rats by long - term high - fat diet intake , then investigate the biochemical , microcirculatory , and histological alterations in blood and pancreatic tissues of these
animals , and discuss their potential significances . -
pubmed
The results showed that the velocity of pancreatic microvascular blood flow of
rats with
hyperlipidemia decreased significantly as compared to control value ( p = 0.008 ) . -
pubmed
Eighty
subjects ( 41
male ) were assigned to one of four groups ( 24 - h deprived or nondeprived dependent smokers , occasional smokers , and nonsmokers ) and participated in an instructed fear conditioning paradigm involving cued administration of electric
shock . -
pubmed
There were also areas of
human immunodeficiency virus (
HIV ) knowledge that were lacking . -
pubmed
Most patients listed the media as their main source of knowledge about
STI and
HIV . -
pubmed
BACKGROUND :
Actinic keratoses (
AKs ) are the most common epithelial
precancerous lesions , especially among
individuals with light complexions . -
pubmed
Patients with grade 3 ( very thick and/or
hyperkeratotic ) lesions were excluded . -
pubmed
The demographics of this study population are typical of a
patient population with
AK . -
pubmed
METHODS : SC and OM adipose tissues were obtained from 10
obese and 11 nonobese
NAFLD patients and from 11
obese and 13 nonobese
patients without
NAFLD , who served as controls . -
pubmed
In this setting , switching strategies may be useful to minimize clinical and psychological consequences , improving the quality of life of
HIV - infected patients treated with HAART . -
pubmed
OBJECTIVE :
Uveitis occurs in 10%-15 % of
patients with
juvenile idiopathic arthritis (
JIA ) . -
pubmed
Neurotoxicosis in 4
cats receiving
ronidazole . -
pubmed
OBJECTIVE : To collect information on clinical practice and current management strategies in 22 Italian neurosurgical hospitals for
patients with
aneurysmal subarachnoid hemorrhage . -
pubmed
PATIENTS : 350 cases of
aneurysmal subarachnoid hemorrhage . -
pubmed
Neurological deterioration ( 24 % ) was more frequent in
patients with higher Fisher classification , and with pretreatment rebleeding and it was associated with an unfavorable outcome ( 46 % , 36/78 , vs. 33 % , 83/251 ) . -
pubmed
Intracranial hypertension was experienced in one - third of the
patients , followed by
hydrocephalus ( 29 % ) and
vasospasm ( 30 % ) . -
pubmed
Infection of the thyroid gland caused by
Campylobacter fetus subsp . - pubmed
We report what we consider to be the first case of an
abscess of the thyroid gland due to
Campylobacter fetus subsp . - pubmed
fetus is known as a rare and opportunistic pathogen in
humans , causing a broad variety of
systemic infections . -
pubmed
It is therefore not unlikely that
human infections caused by
C. - pubmed
METHODS :
Patients with mild
pancreatitis were randomized to a CLD or LFSD when they were ready to resume oral nutrition . -
pubmed
RESULTS : We randomized 121
patients : 66 to
CLD and 55 to LFSD . -
pubmed
RATIONALE :
Patients with refractory
asthma have persistent symptoms despite maximal treatment with inhaled
corticosteroids and long - acting bronchodilators . -
pubmed
OBJECTIVES : To determine the efficacy of
clarithromycin in
patients with severe refractory
asthma and specifically in a subgroup of
patients with
noneosinophilic asthma . -
pubmed
METHODS :
Subjects with severe refractory
asthma ( n = 45 ) were randomized to receive
clarithromycin ( 500 mg twice daily ) or placebo for 8 weeks . -
pubmed
A primate poxvirus (
OrTeCa ) isolated from a
skin lesion in a
rhesus monkey (
Macaca mulatta ) was studied along with four known poxviruses :
vaccinia ,
monkeypox ,
swinepox , and Yaba . -
pubmed
It grows in established lines of
monkey kidney cells at a rate intermediate between that of
vaccinia and
monkeypox and that of
swinepox and Yaba . -
pubmed
Neither can OrTeCa be grown in
rabbit kidney or chick embryo cells or on chick chorioallantoic membranes , all of which support the growth of
vaccinia and
monkeypox viruses . -
pubmed
OrTeCa forms plaques about the same size as those of Yaba and
swinepox viruses , but they appear earlier ; they are morphologically similar to the plaques of
vaccinia and
monkeypox viruses . -
pubmed
The thermal stability of OrTeCa is about the same as that of
vaccinia and
monkeypox but greater than that of
Yaba virus . -
pubmed
We have previously demonstrated that
apigenin , a
plant flavone , causes decreased survival in
human prostate cancer cells . -
pubmed
Efficacy and safety of oral
fumarate in
patients with
relapsing - remitting multiple sclerosis : a multicentre , randomised , double - blind , placebo - controlled phase IIb study . -
pubmed
Our aim was to assess the efficacy and safety of
BG00012 in
patients with
relapsing - remitting multiple sclerosis . -
pubmed
METHODS : 257
patients , aged 18 - 55 years , with relapsing - remitting
multiple sclerosis were randomly assigned to receive 120 mg once daily ( n=64 ) , 120 mg three times daily ( n=64 ) , or 240 mg three times daily ( n=64 )
BG00012 , or placebo ( n=65 ) for 24 weeks . -
pubmed
Adverse events more common in
patients given
BG00012 than in those given placebo included
abdominal pain ,
flushing , and
hot flush . -
pubmed
Dose - related adverse events in
patients on
BG00012 were
headache ,
fatigue , and feeling hot . -
pubmed
Simulation of an early warning system using sentinel birds to detect a change of a low pathogenic
avian influenza virus (
LPAIV ) to high pathogenic
avian influenza virus ( HPAIV ) . -
pubmed
The placement of sentinel birds in a commercial poultry flock infected with low pathogenic
avian influenza virus (
LPAIV ) may be an effective way of detecting subsequent change in the isolate to a high pathogenic
avian influenza virus ( HPAIV ) . -
pubmed
These findings may be used by decision makers to evaluate the risk of not depopulating a flock infected with a H5 or
H7 LPAIV strain and the benefit of using sentinel birds as an early warning system of a change to HPAIV . -
pubmed
Exaggerated pressor responses to mental stress in
patients with
coronary artery disease (
CAD ) are associated with increased risk for subsequent cardiovascular events . -
pubmed
Eighteen healthy
individuals ( aged 61 + /- 8 yr ) and 29
individuals with documented
CAD but no other comorbidities ( aged 59 + /- 8 yr ) were studied . -
pubmed
Characterization of surgical procedures in
patients with
mucopolysaccharidosis type I : findings from the MPS I Registry . -
pubmed
OBJECTIVE : To clarify the extent and chronology of surgical burden in relation to symptom onset and diagnosis in
patients with
mucopolysaccharidosis I (
MPS I ) as reported in the MPS I Registry , an international observational database . -
pubmed
CONCLUSIONS : Pediatricians and pediatric surgeons need to be aware of the surgical burden of
MPS I and be alert to its presenting
signs and symptoms in
children scheduled for surgery . -
pubmed
Our objective was to investigate the role of this gene in a large cohort of
PD patients and controls . -
pubmed
Tuberculins from the avian ,
bovine and
human types of tubercle bacillus as well as " tuberculin " prepared from the Duval and from the Kedrowsky
strains of
M. - pubmed
RESULTS : All
mice exhibited
atherosclerotic lesions in the aortic
sinus and aortic surface . -
pubmed
We further examined the effects of
CCR7 deficiency on the inflammatory response to
P. - pubmed
METHODS : Membranes from eight
patients with active
proliferative diabetic retinopathy and nine
patients with inactive proliferative
diabetic retinopathy were studied by immunohistochemistry . -
pubmed
BACKGROUND : Evaluation of hemostasis in
bleeding patients requires both accuracy and speed . -
pubmed
To assess the ability of this MRI probe as a pH - triggered agent , we utilize a disease
rat model of
cerebral ischemia that produces acidic tissue due to its pathologic condition . -
pubmed
Indacaterol is a novel once - daily ultra - long - acting beta(2)-agonist bronchodilator now approved in the European Union for maintenance bronchodilator treatment of
airflow obstruction in adult
patients with
COPD , to be administered as 150 or 300 microg once - daily dose by means of a single - dose dry powder inhaler . -
pubmed
We present the case of an 80 years old
man , with
upper gastrointestinal bleeding who developed a black esophagus after
hypotensive episodes . -
pubmed
In the present report we describe the clinical , endoscopic and histophatological characteristics of a
patient with a diagnosis of
AEN . -
pubmed
[ Effects of severe
frostbite under
hypoxia on some parameters of
blood coagulation system in
rabbits ] . -
pubmed
Circadian rhythms regulate various functions of
human body , and the disruption of circadian rhythm has been associated with
cancer development and
tumor progression . -
pubmed
Partial daily pattern gene expression recoveries were observed in
patients with
CML with complete cytogenetic response and major molecular response . -
pubmed
METHODS : Consecutive
patients diagnosed with refractory benign
stricture of gastrointestinal tract following Kochman 's criteria were included . -
pubmed
At the end of follow - up ( median follow - up 30 weeks for
esophageal stricture , 33 weeks for
rectal stricture ) 5
patients remained asymptomatic . -
pubmed
Eighty per cent of
patients with
esophageal stenosis showed partial and transient re -
stenosis due to hyperplastic reaction during the degradation of the prosthesis , with transient
dysphagia in two
patients resolved medically . -
pubmed
Emotional modulation of the defense startle reflex ( RMS ) was assessed in 26
women at risk of suffering from
bulimia nervosa ; they were assigned one of to two groups : high craving - trait and low craving - trait . -
pubmed
Comparison of
vildagliptin -
metformin and
glimepiride -
metformin treatments in
type 2 diabetic patients . -
pubmed
METHODS : In a randomized , open - label , comparative study , 106
patients with
type 2 diabetes were enrolled . -
pubmed
The
patient underwent laparoscopic left nephrectomy , and the
tumor was histologically diagnosed as a
sarcomatoid RCC . -
pubmed
At the National Institute for Research in
Tuberculosis , of 1048 LJ slopes with
M. - pubmed
We report the case of an 81 - year - old
man with
oesophageal rupture secondary to
volvulus of an intrathoracic stomach who underwent laparotomy with a repair of the
oesophageal perforation and intrathoracic stomach , making a good recovery . -
pubmed
METHODS : Between December 2002 and November 2010 , 25
patients with
fecal incontinence were treated with gluteus maximus transplantation , which was caused by surgery of high
anal atresia . -
pubmed
CONCLUSION : Gluteus maximus transplantation can improve defecation controls in the
patients with
fecal incontinence after surgery of high
anal atresia . -
pubmed
Shigella are
human - adapted
Escherichia coli that have gained the ability to invade the
human gut mucosa and cause
dysentery(1,2 ) , spreading efficiently via low - dose fecal - oral transmission(3,4 ) . -
pubmed
sonnei has been predominantly responsible for
dysentery in developed countries but is now emerging as a problem in the developing world , seeming to replace the more diverse
Shigella flexneri in areas undergoing economic development and improvements in water quality(4 - 6 ) . -
pubmed
PATIENTS AND METHODS : Four eyes of 4
patients sustained an
IOFB injury with deep impact . -
pubmed
All
patients have long - term follow - up ( mean , 22 months ) with no
postoperative complications . -
pubmed
Value of concomitant endoscopic balloon dilation for
intestinal stricture during long - term
infliximab therapy in
patients with
Crohn ' s disease . -
pubmed
METHODS : The effectiveness of maintenance therapy with IFX was retrospectively evaluated in 185
patients with
CD in a single center ( median observation period 24 months ) . -
pubmed
The efficacy of concomitant EBD in
patients with obstructive symptoms and high - level
stricture was evaluated . -
pubmed
Symptomatic high - level
stricture occurred in 33
patients ( 17.8 % ) in the maintenance group and the cumulative surgery - free rate was significantly higher in the
EBD combination compared with the non -
EBD group ( P & lt ; 0.05 ) . -
pubmed
While percutaneous instrumentation can be generally used in less displaced
fractures , it remains controversial whether such techniques should also be performed in
patients with severe
fracture dislocation . -
pubmed
This includes
patients with severe
traumatic kyphosis and/or
dislocation in the coronar plane , particularly in concomitant
neurological deficits that require additional decompression surgery . -
pubmed
CASE PRESENTATION : The patient was a 76 - year - old
woman who was diagnosed as having
schizophrenia forty years ago . -
pubmed
Functional characterization of T cell populations in a
mouse model of
chronic obstructive pulmonary disease . -
pubmed
Epstein - Barr virus (
EBV ) , a common herpesvirus with high
infection rate , is now suspected to be a risk or protective factor in
food allergy . -
pubmed
METHODS : 34
patients with an
egg allergy and 34 healthy controls participated in this study . -
pubmed
The serotypes and antibiotic resistance of
strains of
S.pneumoniae were determined using the capsular swelling method and the E - test . -
pubmed
CONCLUSIONS :
Serotype 19A strains were most frequently isolated from children with
IPD treated in our hospital . -
pubmed
We applied this methodology to
rat C6 glioma cells and the
Cyprinus carpio and searched the resulting peptide sequences against the protein database . -
pubmed
Chromoendoscopy to detect early synchronous second primary
esophageal carcinoma in
patients with
squamous cell carcinomas of the head and neck ? -
pubmed
To evaluate the use of flexible esophagoscopy and chromoendoscopy with Lugol 's solution in the detection of early
esophageal carcinomas ( second primary
carcinomas ) in
patients with
squamous cell carcinoma of the head and neck (
HNSCC ) . -
pubmed
All
patients with newly diagnosed
HNSCC underwent office - based Lugol 's chromoendoscopy . -
pubmed
132
patients with
HNSCC were enrolled in this study . -
pubmed
Squamous cell carcinomas were detected in two
patients ,
peptic esophagitis in 11
patients ,
gastric heterotopic mucosa in two
patients ,
hyperplasia in two
patients , and low- and
high - grade dysplasia in three patients . -
pubmed
Although only two
patients with synchronous primary
carcinomas were found among the
patients , esophagoscopy should be recommended after detection of
HNSCC to exclude secondary
esophageal carcinoma or
dysplasia . -
pubmed
RESULTS : Twenty - three
patients demonstrated clinical and radiographic evidence of
atlantoaxial instability ( 13
men and 10
women , with a mean age of 42 years ) . -
pubmed
After a period of follow - up , 9 of the 10
neurological deficit patients had completely recovered . -
pubmed
The first patient was a 59 - year - old white
woman treated for a secondary lung nodule of an advanced
hepatocellular carcinoma . -
pubmed
The second
patient was a 61 - year - old white
man followed - up for a
non - small - cell lung cancer . -
pubmed
Due to invasion and intrahepatic
metastasis , the prognosis for
patients with
hepatocellular carcinoma (
HCC ) is poor . -
pubmed
Anaemia to predict outcome in
patients with
acute coronary syndromes . -
pubmed
BACKGROUND : Owing to the heterogeneous population of
patients with
acute coronary syndromes (
ACS ) , risk stratification with tools such as the GRACE risk score is recommended to guide therapeutic management and improve outcome . -
pubmed
METHODS : A prospective registry of 1064
ACS patients ( 63 + - 14 years ; 73 %
men ; 57 % ST - segment elevation
myocardial infarction [
MI ] ) was studied . -
pubmed
Subsequently , adding
anaemia to the GRACE score led to reclassification of 595
patients into different risk categories ; 16.5 % patients at low risk ( & lt;= 5 % risk of
death or rehospitalization for
MI ) were upgraded to intermediate ( & gt;5 - 10 % ) or high risk ( & gt;10 % ) ; 79.5 % patients at intermediate risk were reclassified as low ( 55 % ) or high risk ( 24 % ) ; and 45.5 % patients at high risk were downgraded to intermediate risk . -
pubmed
Rapid Re - challenge with
Clozapine Following Pronounced
Myocarditis in a Treatment - Resistance
Schizophrenia Patient . -
pubmed
Myocarditis is one of the life - threatening adverse effects which occurs in about 1 % of exposed
patients . -
pubmed
[ Effect of
Ca ( OH ) 2 on the
cytotoxicity of lipopolysaccharide extracted from
Porphyromonas endodontalis in vitro ] . -
pubmed
Peripheral T - cell lymphoma in a
child with cutaneous involvement . -
pubmed
PURPOSE : To determine the tear osmolarity in
patients with
tearing secondary to
dry eye and other pathologies , and to determine the prevalence of
dry eye disease among
patients with tearing in an oculoplastics setting . -
pubmed
Patients with
dry eye had a significantly higher median tear osmolarity compared to that in
patients with other diagnoses ( 308 mOsm / L vs. 294 mOsm / L , p & lt ; 0.0001 ) . -
pubmed
CONCLUSIONS : A significant proportion of
patients with tearing in an oculoplastics practice had
dry eye disease . -
pubmed
OBJECTIVES : The purpose of this article is to assess the distribution of undiagnosed
HIV infection in men who have sex with men ( MSM ) in Southern and Eastern European countries , to describe the differences in epidemiology and behaviour between undiagnosed , diagnosed
HIV - positive and HIV - negative MSM and to identify factors associated with undiagnosed
HIV infection in the study population . -
pubmed
RESULTS :
HIV prevalence was 17 % in Barcelona , 12 % in Verona , 6 % in Bratislava , 5 % in Ljubljana , 5 % in Bucharest and 3 % in Prague while undiagnosed
HIV infection was 47 , 62 , 67 , 83 , 85 and 57 % , respectively . -
pubmed
Factors associated with undiagnosed
HIV infection included attending sex - focused venues ( OR = 2.49 ) , reporting
syphilis in the previous 12 months ( OR = 2.56 ) , using poppers at last sexual intercourse ( OR = 3.36 ) and having had an
HIV test in the previous year ( OR = 2.00 ) . -
pubmed
Low
carbohydrates intake , soy protein , omega-3 ( w-3 ) fat ,
green teas ,
tomatoes and
tomato products and
zyflamend showed promise in reducing
PCa risk or progression . -
pubmed
The use of
etanercept in
rheumatoid arthritis patients with
end - stage renal failure has not been well reported . -
pubmed
We report here the case of 58 - years - old
patient who was treated with 50 mg of
etanercept once a week to control the activity of
her disease . -
pubmed
Our case showed the safety and efficacity of
etanercept rheumatoid arthritis in
patient with
end - stage renal failure . -
pubmed
To our knowledge , this is the first case report of
sugammadex use in a
patient with
WPW . -
pubmed
This report presents a case of general anesthesia management in a
patient with
WPW syndrome . -
pubmed
CONCLUSION : We think that it is appropriate to use
sugammadex to reverse
rocuronium for the prevention of sudden hemodynamic changes in
patients with
WPW who underwent general anesthesia . -
pubmed
Tips and tricks for DIEP flap breast reconstruction in
patients with previous abdominal
scar . -
pubmed
All
patients who underwent DIEP flap breast reconstruction between 2004 and 2014 were reviewed and divided into a control group ( CG ) and a
scar group ( SG ) . -
pubmed
With careful preoperative planning and appropriate technical strategies , successfully DIEP flap breast reconstruction can be performed without increased flap and donor - site complications in
patients with preexisting
abdominal scars . -
pubmed
Role and Operative Technique of Portal Venous Tumor Thrombectomy in
Patients with
Pancreatic Neuroendocrine Tumors . -
pubmed
INTRODUCTION :
Venous tumor thrombi have been reported in as many as 33 % of
patients with
pancreatic neuroendocrine tumors (
pNETs ) . -
pubmed
RESULTS : Among 245
patients with
pNET that underwent pancreatectomy at our institution , 26 ( 11 % ) patients required surgical management of
tumor involvement of the portal vein or its tributaries concomitant with pancreatectomy , including 9 ( 3.8 % )
patients who underwent portal venous
tumor thrombectomy . -
pubmed
Among
patients with
pNET who underwent thrombectomy at our institution , all nine had non - functioning
tumors and eight ( 89 % ) had
tumors of the body and/or tail of the pancreas . -
pubmed
CONCLUSION : Venous
tumor thrombectomy may be used to safely and effectively extract
thrombi from the portal venous system in selected
patients with advanced
pNET concomitant with pancreatectomy . -
pubmed
Two
patients in the oPAE group with hypocontractile bladders experienced
recurrence of symptoms and were treated with TURP . -
pubmed
In the TURP group ,
urinary incontinence occurred in 4/15
patients ( 26.7 % ) ,
rupture of the prostatic capsule in 1/15 ( 6.7 % ) , retrograde ejaculation in all
patients ( 100 % ) , and one
patient was readmitted for temporary bladder irrigation due to
hematuria . -
pubmed
MATERIALS AND METHODS : From January 2002 to July 2010 there were 68
patients with advanced stage
cervical carcinoma retrospectively analysed in Maternal and Child Health Hospital of Jiangxi Province . -
pubmed
There were 36
patients ( 29
adenocarcinoma (
AC ) , six
adenosquamous carcinoma (
ASC ) , and one undifferentiated
carcinoma ) classified into observation group that was treated with radical radiation therapy + surgery ( total hysterectomy + bilateral salpingo - oophorectomy ) ; other 32
patients ( 26 AC , five
ASC , and one undifferentiated
carcinoma ) classified into control group that was treated with radical radiation therapy with no further surgery . -
pubmed
BACKGROUND :
People with
eating disorders have difficulties in socio emotional functioning that could contribute to maintaining the functional consequences of the disorder . -
pubmed
This article discusses variants of
oral and oropharyngeal SCC and highlights those features that help distinguish
human papillomavirus - related from
human papillomavirus - unrelated
SCC . -
pubmed
It infects
humans and livestock and causes
Rift Valley fever . -
pubmed
RVFV is considered an agricultural pathogen by the USDA , as it can cause up to 100 % abortion in
cattle and extensive
death of newborns . -
pubmed
In some
human cases of
RVFV infection , the virus causes
fever ,
ocular damage ,
liver damage ,
hemorrhagic fever , and
death . -
pubmed
We then characterized these cells as resistant to new
RVFV infection , but sensitive to other
viral infections , including
Venezuelan Equine Encephalitis Virus (
VEEV ) . -
pubmed
Clinicopathologic Factors Associated With Occult Lymph Node Metastasis in
Patients With Clinically Diagnosed N0
Lung Adenocarcinoma . -
pubmed
BACKGROUND : In some
patients , clinical N0 ( cN0 ) lung
adenocarcinoma diagnosed by preoperative computed tomography scanning and positron emission tomography scanning was staged as pathologic N1 ( pN1 ) or N2 ( pN2 ) postoperatively . -
pubmed
METHODS : We conducted a retrospective chart review of 350
patients treated for cN0
lung adenocarcinoma by curative resection . -
pubmed
RESULTS : Of 350
patients treated for cN0
tumors , 305 ( 87.1 % ) were confirmed postoperatively as having pN0
tumors , and 45 ( 12.9 % ) were confirmed as having pN1 or pN2
tumors . -
pubmed
Finally , we show that the
seizure - prone
ryanodine receptor gain - of - function ( R2474S ) knockin
mice have an unaltered repolarization phase but larger fAHP and increased AP frequency compared with their control littermates . -
pubmed
A healthy microbiota effectively inhibits
infection by restricting the ability of
C. - pubmed
Additionally , there are only a few studies comparing
isoflurane - induced cardiorespiratory effects between
rat strains . -
pubmed
Under anesthesia at more than 4 % , although prolongation of the RR and PR intervals was observed in all
strains , shortening of the QTC interval was found only in SHR / Izm
rats . -
pubmed
Blood pressure and heart rate were remarkably reduced in SHR / Izm
rats at higher concentrations , whereas the reduction was smallest in WKY / Izm
rats among the three
strains examined . -
pubmed
These results suggested that SHR / Izm
rats are more sensitive to suppressive effects of
isoflurane anesthesia on cardiovascular function among these
rat strains . -
pubmed
METHODS : Retrospectively , we examined 210
tremor patients referred for electrophysiological recordings between January 2008 and January 2014 . -
pubmed
The first step was to determine whether
patients met neurophysiological criteria for their type of
tremor . -
pubmed
RESULTS : Most
patients ( 87 % ) concurred with all core clinical neurophysiological criteria for their
tremor type . -
pubmed
METHODS : Nineteen
patients with
anterior circulation aneurysms ruptured during clipping , who admitted to the Department of Neurosurgery , Henan Provincial People 's Hospital from November 2012 to February 2014 , were enrolled . -
pubmed
There was no residual
aneurysm confirmed by postoperative CTA in 17
patients . -
pubmed
The
aneurysm was trapped and the
patient paralysed on one side after operation . -
pubmed
Role of
n-3 Polyunsaturated Fatty Acids in Ameliorating the Obesity - Induced
Metabolic Syndrome in Animal Models and
Humans . -
pubmed
The incidence of
obesity and its comorbidities , such as
insulin resistance and
type II diabetes , are increasing dramatically , perhaps caused by the change in the
fatty acid composition of common
human diets . -
pubmed
METHODS :
CSP was identified and graded with 16 slice computed tomography ( CT ) machine in 138
patients of
schizophrenia and 64 controls . -
pubmed
RESULTS : We found 21.0 % of
patients in
schizophrenia group had abnormal
CSP compared to only 9.4 % in control group ( P = 0.047 ) . -
pubmed
These findings should promote awareness among physicians to make a timely diagnosis of
HIV and to help physicians prioritize prevention and intervention strategies for
anemia in
HIV - infected patients . -
pubmed
Seventy - eight
patients subsequently developed
MDS and nine patients developed
CMML during 402 892 person - years . -
pubmed
Given the robust results in preclinical models and mixed results in observational studies , controlled dietary interventions with standardized intakes are needed to better understand the interaction of specific fat and fiber subtypes on colon biology and ultimately
CRC susceptibility in
humans . -
pubmed
Studies on the antidiabetic activities of
Momordica charantia fruit juice in
streptozotocin - induced
diabetic rats . -
pubmed
CONTEXT :
Momordica charantia Linn (
Cucurbitaceae ) ( MC ) is used in folk medicine to treat various diseases including
diabetes mellitus . -
pubmed
OBJECTIVE : This study investigates the antidiabetic activities of
Momordica charantia (
bitter gourd ) on
streptozotocin - induced
type 2 diabetes mellitus in
rats . -
pubmed
CONCLUSIONS :
Momordica charantia presents excellent antidiabetic and antioxidant activities and thus has great potential as a new source for
diabetes treatment whether it is used for prophylaxis or treatment . -
pubmed
In
ALS mouse models ,
edaravone suppresses motor functional decline and nitration of
tyrosine residues in the cerebrospinal fluid . -
pubmed
In all trials , the primary outcome measure was the changes in scores on the revised
ALS functional rating scale ( ALSFRS - R ) to evaluate motor function of
patients . -
pubmed
Long - Term Outcomes of a Large Cohort of
Patients with
Eales ' Disease . -
pubmed
This systematic review and NMA aimed to evaluate the safety and efficacy of different antifungal agents used for prophylaxis of
IFI in
patients with
haematological disorders . -
pubmed
Preimplantation genetic diagnosis is a subtype of
IVF in which embryos are created for genetic diagnosis of
hereditary disorders in order to avoid genetically affected
children . -
pubmed
Patients with traumatic
cataract ,
corneal diseases , and
preoperative astigmatism & gt;1.5 D were excluded from the study . -
pubmed
CONCLUSION : SICS and phacoemulsification with this technique yield lesser
astigmatism than clear corneal and scleral incisions , with the advantage of extension without suturing in complicated cases of phaco and in
patients with rigid intraocular lens phacoemulsification gives better BCVA in a larger proportion of
patients at 12 weeks . -
pubmed
Circadian blood pressure patterns and blood pressure control in
patients with
chronic kidney disease . -
pubmed
METHODS : In this observational study , we studied 547
patients referred to the
hypertension clinic , of whom 224 ( 40.9 % ) had
CKD . -
pubmed
Patients with
CKD presented as twice as higher prevalence of reverse dipper ( night - time peak ) for systolic BP and episodes of
hypotension during daytime , independently of BP control . -
pubmed
The case is presented on a 72 year - old
woman with uncontrolled
high blood pressure referred to the Urology Department due to the incidental finding of a right retroperitoneal mass . -
pubmed
INTRODUCTION AND HYPOTHESIS : Our aim was to evaluate clinically relevant long - term outcomes of transvaginal mesh or native tissue repair in
women with recurrent
pelvic organ prolapse (
POP ) . -
pubmed
METHODS : We performed a 7 - year follow - up of a randomized controlled trial on trocar - guided mesh placement or native tissue repair in
women with recurrent
POP . -
pubmed
These include whole cell - based screenings ,
zebrafish larvae - based screenings and the impact of artificial
granuloma research on the drug discovery process . -
pubmed
Objectives : This study investigates the prediction of
Non - small cell lung cancer (
NSCLC )
patient survival outcomes based on radiomic texture and shape features automatically extracted from
tumor image data . -
pubmed
Spearman 's rank correlation , Kaplan - Meier estimation and log - rank tests were used to identify features related to long / short
NSCLC patient survival groups . -
pubmed
Immune Consequences of in vitro
Infection of
Human Peripheral Blood Leukocytes with Vesicular Stomatitis Virus . -
pubmed
BACKGROUND : Oncolytic
vesicular stomatitis virus (
VSV ) can be delivered intravenously to target primary and metastatic lesions , but the interaction between
human peripheral blood leukocytes ( PBLs ) and
VSV remains poorly understood . -
pubmed
Our study aimed to assess the overall immunological consequences of ex vivo
infection of PBLs with
VSV . -
pubmed
Our results shed further light on immune mechanisms in response to
VSV infection and the underlying
VSV - PBL interactions bringing hope for improved
cancer immunotherapies , particularly those based on intravenous delivery of oncolytic
VSV . -
pubmed
Radiotherapy ( RT ) is applied in
prostate cancer patients with a biochemical
recurrence ( BcR ) after radical prostatectomy ( RP ) . -
pubmed
In all of the eight cases of vertical transmission , the diagnosis was after the birth of children infected with
HBV , and in 3/8 ( 37.5 % ) , there was more than one case of
infection by this mechanism per patient , totaling 13 children with the disease . -
pubmed
majus excreted broad antifungal activity against Penicillium , Aspergillus and
non - albicans Candida isolates comprising
strains both sensitive and resistant to
fluconazole . -
pubmed
Additionally , it showed no
cytotoxicity on
human cells and the chemical characterization of the
H. - pubmed
CONCLUSION : In
patients with moderate to severe
AVVR , restoration of atrioventricular valve competence prior to , or at the time of , Stage 2 surgery would likely lead to improved haemodynamics and clinical outcome as the models suggest that uncorrected AVVR can worsen across Stage 2 surgery . -
pubmed
Furthermore , the antifungal activity of the as - prepared
Ag NPs was tested against
Cladosporium fulvum , which is the major cause of a serious
plant disease , known as
tomato leaf mold . -
pubmed
Patients with
metastatic RCC have an unusually poor prognosis and near - universal resistance to all current therapies . -
pubmed
To improve
RCC treatment and the survival rate of
patients with
RCC , there is an urgent need to reveal the mechanisms by which metabolic reprogramming regulates aberrant signaling and oncogenic progression . -
pubmed
METHODS : Electronic and manual literature searches were conducted on PubMed / MEDLINE and the Cochrane Library on studies published until May 2018 to collect information about the effect of machined , moderately rough , and rough dental implant surfaces in
patients with a history of
periodontal disease . -
pubmed
Accumulation and
toxicity of
thiamethoxam and its metabolite
clothianidin to the gonads of
Eremias argus . -
pubmed
The significant declines in
testosterone and
prostaglandin D2 levels in the plasma indicated that
thiamethoxam and
clothianidin could cause
androgen deficiency in
male lizards . -
pubmed
BACKGROUND : Exercise is prescribed for
people with
Parkinson ' s disease to address motor and non - motor impairments , including
pain . -
pubmed
, an immediate reduction in
pain sensitivity following exercise ) is reported in the general population ; however , the immediate response of
pain sensitivity to exercise in
people with
Parkinson ' s disease is unknown . -
pubmed
The purpose of this study was to investigate if exercise - induced
hypoalgesia is present following isometric and aerobic exercise in
people with
Parkinson ' s disease , and if so , if it varies with the dose of aerobic exercise . -
pubmed
METHODS : Thirty
people with
idiopathic Parkinson ' s disease and
pain - free age - matched controls completed two observational studies evaluating the response to : ( a ) right arm isometric exercise ; and ( b ) treadmill walking at low and moderate intensities . -
pubmed
CONCLUSIONS : Overall ,
people with
Parkinson ' s disease experienced an exercise - induced
hypoalgesia response similar to that of the control group , the extent of which did not vary between mild and moderate doses of aerobic exercise . -
pubmed
SIGNIFICANCE : Isometric and aerobic exercise reduces
pain sensitivity in
people with
Parkinson ' s disease . -
pubmed
The
dog developed a self - resolving
seroma . -
pubmed
METHODS : A total of 969 pregnant
women were randomly screened in first and second trimester , of which 8 developed Early - onset
Preeclampsia , 29 Late - onset
Preeclampsia , 35
Gestational Hypertension and 897
women had a normal outcome . -
pubmed
Methods :
Patients with controlled and uncontrolled
acromegaly and as a control group ( CG )
patients without
acromegaly between January 2010 and March 2014 were included . -
pubmed
Results : Fifty - nine
patients with
acromegaly ( controlled n=30 , uncontrolled n=29 ) and 73 age and gender matched
volunteers without
acromegaly were evaluated . -
pubmed
Six ( 20 % ) of controlled
acromegaly patients , 10 ( 35 % ) of uncontrolled
acromegaly patients and three ( 4 % ) of CG had inadequate bowel cleansing ( p<0.001 ) . -
pubmed
A 60 - year - old
female presented with cervical
spinal cord compression caused by
IgG4 - RD leading to several
neurological deficits . -
pubmed
Our aim was to investigate the possible role of inflammasome in the chronic subclinical inflammatory condition typical of
RTT , by analyzing this complex in basal and
lipopolysaccharide ( LPS )+ ATP - stimulated primary fibroblasts , as well as in serum from
RTT patients and healthy volunteers . -
pubmed
Is surveillance imaging in pediatric
patients treated for
localized rhabdomyosarcoma useful ? -
pubmed
BACKGROUND : After the completion of therapy ,
patients with
localized rhabdomyosarcoma (
RMS ) are subjected to intensive radiological
tumor surveillance . -
pubmed
This study retrospectively analyzed the value of off - therapy surveillance by comparing the survival of
patients in whom
relapse was detected by routine imaging ( the imaging group ) and
patients in whom
relapse was first suspected by symptoms ( the symptom group ) . -
pubmed
METHODS : This study included
patients with
relapsed RMS after the completion of therapy for
localized RMS who were treated in large pediatric oncology hospitals in France , the United Kingdom , Italy , and the Netherlands and who were enrolled in the International Society of Paediatric Oncology
Malignant Mesenchymal Tumor 95 ( 1995 - 2004 ) study , the Italian Paediatric Soft Tissue
Sarcoma Committee
Rhabdomyosarcoma 96 ( 1996 - 2004 ) study , or the European Paediatric Soft Tissue
Sarcoma Study Group
Rhabdomyosarcoma 2005 ( 2005 - 2013 ) study . -
pubmed
The survival times after
relapse were compared with a log - rank test between
patients in the imaging group and
patients in the symptom group . -
pubmed
RESULTS : In total , 199
patients with relapsed
RMS were included : 78
patients ( 39.2 % ) in the imaging group and 121
patients ( 60.8 % ) in the symptom group . -
pubmed
This study found no survival advantage for
patients whose
relapse was detected before the emergence of clinical symptoms . -
pubmed
Regulatory effect of Garidisan on
dysbiosis of the gut microbiota in the
mouse model of
ulcerative colitis induced by dextran sulfate
sodium . -
pubmed
Garidisan is composed of wild
poppy and
Artemisia frigida Willd and is commonly used for the treatment of
UC in Inner Mongolia , China . -
pubmed
Previous studies have shown that Garidisan has a good therapeutic effect on
mice with
UC , but the therapeutic mechanism is still unclear . -
pubmed
In this study , we investigated the regulatory effect of Garidisan on
dysbiosis of the gut microbiota in a
UC mouse model and explored the possible mechanism of the therapeutic effect of Garidisan on
UC . -
pubmed
BACKGROUND :
Enterovirus 71 (
EV71 ) is the main pathogen that causes severe
hand , foot , and mouth disease with fatal
neurological complications . -
pubmed
This study reports the hen health and welfare portion based upon veterinary health inspections and compared mortality rates ,
skeletal abnormalities , causes of
death determined by necropsy , and titers to
infectious bronchitis and
Newcastle disease viruses . -
pubmed
We compared the outcomes among
patients who were managed with pre - emptive
pain management program with enhanced recovery after surgery ( Pre - emptive ) , enhanced recovery program after surgery alone ( ERAS ) and standard care ( control ) . -
pubmed
Results : Of the 443
patients , 132
patients ( 30 % ) were in the pre - emptive
pain management group , 90 ( 20 % )
patients were in the ERAS only group and 221 ( 50 % ) in the control group . -
pubmed
Multivariate logistic regression analyses showed that the pre - emptive
pain management program ( OR 0.06 ; 95 % CI , 0.03 , 0.11 , P<0.001 ) and robotic surgery ( OR 0.52 ; 95 % CI , 0.3 , 0.88 , P=0.02 ) were associated with lower odds of
patients being discharged to home with opioid prescriptions . -
pubmed
Association of left ventricular volume in predicting clinical outcomes in
patients with
aortic regurgitation . -
pubmed
METHODS : We retrospectively analyzed 1100 consecutive
patients with chronic moderate - severe and severe
AR by echocardiography between 2004 and 2019 . -
pubmed
To enhance understanding of the molecular nature of renal aging , we first compared whole - kidney RNA sequencing between naturally aging
mice ( 24 - month - old ) and
adenine - induced
nephropathy in young
mice ( 2 - month - old ) . -
pubmed
Next , we compared the functional and structural renal consequences of aging and
adenine - induced
nephropathy between young ( 2 - month - old ) and old
mice ( 18- to 22 - month - old ) . -
pubmed
When
mice were fed with
adenine - enriched diet , aging kidneys showed more extensive
tubular injury and
fibrosis with stronger inflammatory response than young kidneys . -
pubmed
Endocarditis due to
Staphylococcus lugdunensis - a retrospective national registry - based study . -
pubmed
We present characteristics of
infective endocarditis (
IE ) caused by
Staphylococcus lugdunensis and compare with
IE caused by
Staphylococcus aureus and other CoNS , in the National Swedish Registry of IE ( 2008 - 2018 ) . -
pubmed
lugdunensis
IE ( 20 % , n = 6 ) , than for
IE caused by other CoNS ( 7 % ) or
S. - pubmed
Preclinical opioid research using
animal models not only provides mechanistic insights into the modulation of opioid analgesia and its associated side effects , but also validates drug candidates for improved treatment options for
opioid use disorder . -
pubmed
Data collected included
patient characteristics , serum
creatinine ( SCr ) level before and after TAE ,
iodine quantity of
contrast media , time between computed tomography and TAE ,
diabetes mellitus ,
hemorrhage volume , and blood transfusion volume . -
pubmed
Postpartum
hemorrhage was finally controlled in all 47
patients , and they were subsequently discharged . -
pubmed
In conclusion , emergency TAE for
patients with uncontrollable postpartum
hemorrhage was a safe and effective procedure , not only in terms of bleeding - related and other outcomes but also with respect to the risk of PC -
AKI . -
pubmed
Postoperatively ,
patients are at risk of severe
hypocalcemia and
hungry bone syndrome requiring close monitoring and replenishment . -
pubmed
We investigated glycocalyx components in relation to
preeclampsia in
human samples . -
pubmed
Histopathological and lipid changes in various organs of
chicks (
Gallus domesticus ) caused by acute and chronic
toxicity of
metasytox - R and
lebaycid . -
pubmed
Different response to
phalloidin in
rats with various
hepatomas . -
pubmed
[ Special aspects of intensive care for
comatose patients in surgical medicine ] . -
pubmed
Capsaicin treatment of newborn
rats results in the degeneration of primary sensory neurones involved in the mediation of chemogenic
pain . -
pubmed
Thirty fit
patients ( 15 - 70 years , 46 - 98 kg ) undergoing body - surface operations were selected to include a wide range of adiposity ( 12 - 45 % of total
body weight estimated from measurements of skinfold thickness ) . -
pubmed
Thus
ImAA joins
histamine and the
tetrapeptides ( ECF - A ) as
anaphylaxis - associated selective chemoattractants for
human eosinophils -
pubmed
The echocardiographic findings in a 73 - year - old
woman with constrictive calcified
pericarditis are presented . -
pubmed
In 373 hospitalized
patients with bacteriologically positive bile samples , the aetiology was clarified by laboratory methods in 80 % of clinically verified
gallbladder and biliary duct infections and in 15.5 % of diseases related to the biliary duct . -
pubmed
Vincristine sulphate may benefit some
patients and splenectomy is indicated in
patients with severe uncontrollable
haemorrhage . -
pubmed
Right brain - damaged
patients with
left spatial neglect were examined on a tactile maze task . -
pubmed
Pharmacological manipulations of
anoxia - induced free
fatty acid accumulation in the
mouse brain . -
pubmed
The accumulation of free
fatty acid (
FFA ) in the brain occurs within minutes of
anoxia , induced by exposing
mice to a 100 %
N2 atmosphere . -
pubmed
[ Changes in the phase structure of the left ventricle systole in
patients with obliterative
atherosclerosis of the lower extremities after treatment with
naphthalane baths ] . -
pubmed
Fifty six
patients with
IHD and
stenocardia ,
hypertensive disease were treated at the Naphthalan health resort . -
pubmed
It was found that
napthalane baths in the sitting position stimulate adaptation reserves of the body , improve the cardiac function , systemic and regional hemodynamics and may be used in the complex treatment of
patients with obliterative
atherosclerosis of the lower extremities including association of this disease with
IHD and
hypertension . -
pubmed
Autonomic nervous system dysfunction and volume nonresponsive
hypotension in hemodialysis
patients . -
pubmed
Studies were conducted in 9 dialysis
patients with volume - nonresponsive
hypotension , 6 dialysis
patients with volume - responsive
hypotension and in 10 normal subjects in an effort to evaluate the role of
dysfunction of the autonomic nervous system ( ANS ) in the genesis of volume - nonresponsive
hypotension . -
pubmed
Patients with volume - nonresponsive
hypotension displayed significant derangements in the function of ANS as compared to normal subjects and to
patients with volume - responsive
hypotension . -
pubmed
Data show that dysfunction of ANS plays an important role in the genesis of volume - nonresponsive
hypotension in dialysis
patients . -
pubmed
We now report the detection of potentially activating mutations of the
human FMS gene in vivo . -
pubmed
As many as 139
patients with
dilated cardiomyopathy were examined for the effect of the clinical , ECG , x - ray , phono- , echo- and angiocardiographic indicators and heart catheterization data on the disease outcomes for 3 years after the examination . -
pubmed
Subclinical
hepatotoxicity developed in 5
patients . -
pubmed
Patients who had
hepatic and / or pulmonary abnormalities develop received higher doses of
amiodarone ( 440 + /- 27 vs 340 + /- 18 mg / day ) , but also had a higher
amiodarone :
DEA ratio suggesting that dose - dependent kinetics contributed to the higher concentrations . -
pubmed
The haemodynamic dose - response effects of intravenous
amrinone were measured in 16 male
patients , aged 40 - 65 years , with radiographic and haemodynamic evidence of
left ventricular failure 4 - 18 h after acute
myocardial infarction . -
pubmed
Experimental combined hormone therapy on
human breast carcinomas serially transplanted into
nude mice . -
pubmed
Experimental combined hormone therapy with
tamoxifen ,
aminoglutethimide and
medroxyprogesterone acetate was investigated using three hormone - dependent
human breast carcinomas serially transplanted into
nude mice . -
pubmed
It was shown that in
nephropathy , the orderliness parameter increases and the hydrophoby of probe I localized in a red cell suspension of
nephropathy patients diminishes as compared with analogous parameters in healthy pregnant women . -
pubmed
In a prospective investigation the clinical relevance of endoscopically confirmed
lesions of the glenoid labrum in 46
patients is examined . -
pubmed
A case of
giant cell myocarditis in a
patient with
non - Hodgkin ' s lymphoma is reported . -
pubmed
In vitro
erythrocyte agglutination developed in 3 hospitalized
horses receiving
heparin treatment . -
pubmed
Similar abnormalities in erythrocyte counts and
MCV have been reported in healthy
horses treated with
heparin and have been cited as evidence of
hemolysis and regenerative
anemia . -
pubmed
Since urine culture and urinalysis are both of uncertain reliability in diagnosing symptomatic
urinary tract infections in patients with chronic urinary catheters , we performed sequential quantitative cultures and urinalyses on 177 urine specimens from 14
patients with long - term urinary catheters during a 12 - month period . -
pubmed
Gastritis ,
duodenogastric reflux and bacteriology of the gastric remnant in
patients operated for
peptic ulcer by Billroth I operation . -
pubmed
Duodenogastric reflux was significantly greater in the gastrectomized
patients than in the controls . -
pubmed
Of the operated
patients , 6 % had normal stump mucosa and 80 % had
atrophy . -
pubmed
[
Mesotheliomas in
golden hamster . -
pubmed
[ Summary of recent virological studies in
human hemopathies ] . -
pubmed
[ The
hypokalemia and
kaliuresis after intravenous administration of a sympathomimetic in
man ] . -
pubmed
[
Eosinophilia in the
rat uterus following
estrogen treatment ] . -
pubmed
[ The effect of the serum of
patients with various forms of
diabetes mellitus on the lipolytic activity and
glucose uptake of the adipose tissue ] . -
pubmed
The neuroendocrine system of normal
human appendix , ileum and colon , and in
neurogenic appendicopathy . -
pubmed
[ Detection and characterization of the plasmids of the
plague microbe which determine the synthesis of
pesticin I , fraction I
antigen and "
mouse " toxin exotoxin ] . -
pubmed
Phagocytosis and transport of
carbon particles in the
glomerular lesions caused by
Habu snake venom ] . -
pubmed
[ Early and late results of aorto - coronary bypass surgery in the
children with
Kawasaki disease ( author 's transl ) ] . -
pubmed
Short - term parenteral and peroral
testosterone administration in
men with
alcoholic cirrhosis . -
pubmed
Serum concentrations of
testosterone were measured in 24 male
patients with
alcoholic cirrhosis during
testosterone administration . -
pubmed
This ligament is the most frequently disrupted ligament in the
human knee , yet wide disagreement exists concerning the effects of its
rupture and the appropriate means of treatment . -
pubmed
In 15
patients with
chronic active hepatitis the median hepatic
copper content was 39 micrograms / g dry weight at the start and 28 micrograms / g dry weight at the end of the observation period , during which the clinical condition was improved in most
patients . -
pubmed
The hepatic
copper content did not change significantly ( 41 versus 54 micrograms / g dry weight ) in 28
patients with
hepatobiliary disorders associated with
inflammatory bowel disease . -
pubmed
In 27
patients with
primary biliary cirrhosis the median hepatic
copper concentration was initially 176 micrograms / g dry weight , and at the follow up 186 micrograms / g dry weight . -
pubmed
[ Chronic experimental
allergic neuritis as an experimental model of
human idiopathic chronic polyradiculoneuropathy ] . -
pubmed
Evaluation of
ototoxicity of
amino - glycoside antibiotics in
rabbits . -
pubmed
The
ototoxicity was
GM greater than
DKB greater than KM greater than
AMK with the dose of 100 mg / kg , which coincide with many of the conventional reports on
animal experiments . -
pubmed
Usually , the doses of drugs used in the
ototoxicity studies with
animals are more than 10 times higher than those used clinically . -
pubmed
Consequently , problems still exist in infering the
ototoxicity of drugs in
humans directly from the results obtained from
animal experiments . -
pubmed
Even so , high values give an effective expression of its progress by identifying
patients with a greated likelihood of
recurrence . -
pubmed
Effect of
androgen depletion on postoperative regrowth of
androgen - dependent and -independent Shionogi
carcinomas in
mice . -
pubmed
After 20 or 15 days , most of the developed
tumors were excised and the
mice were divided into 3 groups . -
pubmed
The cumulative 120 - day mortality after transplantation of
SC115 tumor into
mice was significantly lower in the immediate
androgen removal group ( 10 % , 6/59 ) than in the
androgen - injected group ( 59 % , 51/87 ) or the delayed
androgen removal group ( 42 % , 19/45 ) . -
pubmed
The cumulative mortalities in
mice with
androgen - independent
NHD and NHF
tumors in the immediate
androgen removal groups ( 97 and 91 % , respectively ) were similar to those in the
androgen - injected groups ( 90 and 95 % , respectively ) . -
pubmed
All non - operated and TP - injected
mice grafted with SC115 and
androgen - independent
tumor died due to the
tumors within 50 and within 30 days after the transplantation , respectively . -
pubmed
METHODS : A 17 - year - old
female presented with a left
intraventricular and intraparenchymal cerebral hemorrhage resulting from a 1 cm left
posterior choroidal AVM . -
pubmed
CONCLUSION : We recommend that
patients with angiographic obliteration of
AVMs receive further treatment , preferably resection , or be followed with serial angiography . -
pubmed
Evidence of antitumor effect was noted particularly among untreated
patients with
gastrointestinal primaries . -
pubmed
Is
man helpless against
cancer ? -
pubmed
The effect of
zinc deficiency on wool growth and skin and wool follicle histology of male
Merino lambs . -
pubmed
The aims of this work were to quantify the requirements of
Zn for wool growth in growing male
Merino lambs , and to describe the histological lesions of
Zn deficiency in skin and wool follicles . -
pubmed
Sheep fed on the diet containing 4 mg
Zn / kg showed clinical signs of
Zn deficiency and lower feed intakes and wool growth than
sheep in the other groups . -
pubmed
Sheep from other groups showed no clinical signs of
Zn deficiency , and mean feed intakes and growth rates did not differ significantly between
sheep fed on diets containing 10 , 17 or 27 mg
Zn / kg . -
pubmed
Electromyographic studies of 15 obturator internus muscles in 10 healthy adult male
volunteers and 3 other muscles in
patients with documented
spastic anal sphincters demonstrated the ability of the obturator internus muscles to contract during straining at stools . -
pubmed
The proposed surgical approach was studied in 9
cadavers ( 5
stillbirths and 4
adults ) , followed by formal anatomical dissection of the obturator internus muscle and tendon , pudendal nerve and vessels , inferior rectal nerve and nerve to the obturator internus . -
pubmed
We evaluated the effectiveness and safety of
zinc in 5
patients with
Wilson ' s disease aged from 19 to 40 years . -
pubmed
From the present study it can be concluded that
nodular hyperplasia represents
monoclonal parathyroid neoplasia , which might explain why
patients with
nodular hyperplasia in
renal hyperparathyroidism are refractory to medical treatment , requiring parathyroidectomy . -
pubmed
A
cough - induced increased in intra - abdominal pressure was recorded vaginally in 26
women with
stress incontinence and
urinary leakage was detected electronically . -
pubmed
Campylobacter jejuni isolates from two epidemic outbreaks in Sweden , one milkborne ( 35 isolates ) and one waterborne ( 17 isolates ) , and one waterborne outbreak in Norway ( 11 isolates ) , as well as 30 solitary isolates from Swedish patients with
gastroenteritis , were analyzed . -
pubmed
PURPOSE : To evaluate the combination of
vinorelbine ,
ifosfamide and
cisplatin (
VIP ) in
patients with advanced
non - small - cell lung cancer (
NSCLC ) . -
pubmed
We report on 2 cases of
cardiac hemangioma , diagnosed occasionally in the first
patient or due to
gastroenteric symptoms in the second
patient . -
pubmed
Both
patients underwent
tumor resection in hypothermic cardiopulmonary bypass . -
pubmed
Effect of combination therapy of
troglitazone and
sulphonylureas in
patients with
Type 2 diabetes who were poorly controlled by
sulphonylurea therapy alone . -
pubmed
Two hundred and ninety - one
patients with
Type 2 diabetes ( age 21 - 81 years ) whose previous glycaemic control by
sulphonylureas was judged stable but unsatisfactory ( fasting plasma
glucose ( FPG ) & gt ; 8.3 mmol I-1 ) were randomly allocated into the
troglitazone treatment group (
troglitazone group , n = 145 ) or the placebo treatment group ( placebo group , n = 146 ) . -
pubmed
The cumulative
patient survival estimated by the Kaplan - Meier method showed a worse prognosis for
patients belonging to group 1 , where higher AgNOR values , not only in primary
carcinomas but also in lymph node and distant
metastases , were found . -
pubmed
Changes of ultrasonography and two serum biochemical indices for
hepatic fibrosis in
schistosomiasis japonica patients one year after
praziquantel treatment . -
pubmed
OBJECTIVE : To observe the changes of abdominal sonography and 2 biochemical indicators for
hepatic fibrosis before and after treatment with
praziquantel in
schistosomiasis japonica patients . -
pubmed
CONCLUSIONS : Parameters of hepatic
fibrosis either by ultrasonography or by the 2 biochemical tests showed a significant improvement in 55
patients 1 year after treatment , although some of the indices did not yet return to normal levels . -
pubmed
Analysis of the clinical case material , covering 382
patients with diagnosis
diabetic gangrene , is done with the purpose to reduce the percentage of disabling high - level amputations , and determine with precision the scope of operative activity , indications for operative intervention and type of surgical procedure in
diabetic patients . -
pubmed
These results are consistent with a specific acute inflammatory component to
TBI in
children . -
pubmed
STUDY DESIGN : This prospective study used 87
subjects diagnosed by their
physicians with unilateral
benign paroxysmal positional vertigo of the posterior semicircular canal . -
pubmed
[ Seroepidemiological survey of
TT virus ( TTV ) infection in an endemic area for
hepatitis C virus ] . -
pubmed
Seroepidemiological survey of
TT virus ( TTV ) infection was performed in the inhabitants living in an endemic area for
hepatitis C virus (
HCV ) in Gifu prefecture , Japan . -
pubmed
The
TTV DNA - positive rate of the inhabitants with
HCV infection was 21.4 % higher than that of the inhabitants without
HCV infection 10.0 % . -
pubmed
In the present survey , the rate of
liver dysfunction of
TTV DNA - negative inhabitants was not different from that of
TTV DNA - positive inhabitants . -
pubmed
Chronic
alcohol treatment impairs host response to
bovine mycobacterium infection from BCG . -
pubmed
Central nervous system ( CNS ) pathology was the main cause of
death in 17 % of the
patients ( n = 31 ) , with a predominance of
IHP in this particular group . -
pubmed
001 ) and
toxoplasmosis ( 9.67 vs 4.44 % ) ( P & lt ; 0.001 ) were significantly more frequent in the group of
patients who died due to CNS causes than in the control group . -
pubmed
METHOD : A single - center , blinded study in otherwise healthy
humans ( n= 52 ) with localized mild to moderate
AP was carried out , using the following groups : group A ( n= 12 ) , no oral hygiene for 14 days ; group B ( n=20 ) , routine oral hygiene ( ROH ) for 14 days ; group C ( n=20 ) , supra - gingival oral irrigation plus ROH for 14 days . -
pubmed
Severe
fungal infections were noted in 2
patients treated with
MMF . -
pubmed
Malignancy occurred in 1
patient (
pancreas graft lymphoma ) in
MMF . -
pubmed
Cyclophosphamide in the treatment of
idiopathic pulmonary fibrosis : a prospective study in
patients who failed to respond to
corticosteroids . -
pubmed
STUDY OBJECTIVES : To prospectively examine the role of
cyclophosphamide in
patients with
idiopathic pulmonary fibrosis that is unresponsive to or intolerant of high - dose
steroid treatment . -
pubmed
PATIENTS : Nineteen
patients with biopsy specimen - proven usual
interstitial pneumonia who failed to respond ( n = 16 ) or experienced adverse effects ( n = 3 ) from
corticosteroid treatment ( 1 mg / kg / d for 3 months ) . -
pubmed
Toxicity associated with
cyclophosphamide was substantial ; more than two thirds of the
patients developed drug - related adverse effects , and almost half discontinued the drug prematurely due to side effects . -
pubmed
CONCLUSIONS :
Cyclophosphamide therapy is of limited efficacy in
patients with
idiopathic pulmonary fibrosis who fail to respond or who experience adverse effects from
corticosteroid treatment , and adverse effects often complicate its use . -
pubmed
Characterisation of the biochemical and biological variations from the venom of the
death adder species (
Acanthophis antarcticus ,
A. - pubmed
We report on species variation in the venoms of the three species of
death adder ; the Common
death adder (
Acanthophis antarcticus ) , the
Northern death adder (
Acanthophis praelongus ) and the Desert
death adder (
Acanthophis pyrrhus ) . -
pubmed
Actinobacillus suis infection in
pigs in Australia . -
pubmed
Comparative analysis of the whole set of rRNA operons between an enterohemorrhagic
Escherichia coli O157 : H7 Sakai
strain and an
Escherichia coli K-12 strain MG1655 . -
pubmed
We have managed 25
patients with
TCA , of whom 5 had total intestinal involvement and died . -
pubmed
It is unethical and incompetent to deny the scale and nature of
human reactions to
trauma . -
pubmed
During the course of a large - scale clinical trial , a subset of
patients reported the onset of
symptoms and signs of
cardiac failure that appeared to be aggravated by concomitant exposure to
anthracyclines . -
pubmed
However , new insights into the pathways that lead to other forms of
heart failure have identified a pivotal role for myocyte survival pathways in preventing the onset of
cardiomyopathy and associated
heart failure in genetically engineered
animal models of the disease . -
pubmed
The possibility exists that the divergent susceptibility for the onset of
cardiotoxicity among
patients who have received
trastuzumab might ultimately reflect an inherent
genetic susceptibility to the diverse mechanisms that initiate , promote , and suppress the complex pathways to
heart failure . -
pubmed
METHODS AND RESULTS : Sixteen
pigs with
left ventricular hypertrophy (
LVH ) secondary to ascending aortic banding and 10 normal
pigs ( N ) were studied . -
pubmed
Nine of the 16
animals with
LVH developed
congestive heart failure (
CHF ) , as evidenced by
ascites ( 100 to 2000 mL ) . -
pubmed
BACKGROUND : PCR protocol for
Vibrio cholerae , the causative agent of the
diarrheal disease cholera has been described in this report . -
pubmed
Recombinant antigens to establish a model of
autoimmunity in
mice . -
pubmed
We applied this technique in a
woman who had received sterilising chemotherapy for
lymphoma . -
pubmed
METHODS : A 36 - year - old
woman underwent a right oophorectomy with cryopreservation of ovarian cortical strips before receiving high - dose CBV chemotherapy for a third
recurrence of
Hodgkin ' s lymphoma . -
pubmed
FINDINGS : 7 months after reimplantation of ovarian cortical strips , the
patient reported resolution of
hot flashes and , for the first time ,
oestradiol was detected in the serum . -
pubmed
The
patient had one menstrual period , but by 9 months after the implantation , her sex
steroid concentrations had returned to those seen with
ovarian failure . -
pubmed
INTERPRETATION : Orthotopic reimplantation of frozen / thawed ovarian cortical strips is a well tolerated technique for restoring ovarian function in
women treated with sterilising chemotherapy for
cancer . -
pubmed
Venous thrombosis in
patients with
solid tumors : determination of frequency and characteristics . -
pubmed
Irinotecan appears active and relatively well tolerated in
patients with relapsed aggressive or indolent
NHL . -
pubmed
We reviewed our experience over a 5 - year period and identified eight adult
patients with incapacitating respiratory symptoms compatible with
HPS . -
pubmed
Underlying
liver disease was caused by
hepatitis C ( 2
patients ) , primary
biliary cirrhosis ( 1 patient ) ,
cryptogenic cirrhosis ( 1 patient ) ,
alcohol ( 2 patients ) , and
hepatitis C with
alcohol ( 2 patients ) . -
pubmed
Severe
hypoxemia was present in seven
patients ( Pa(O2 ) 51.5 + /- 8.2 mm Hg ) . -
pubmed
Three
patients had complicating
pulmonary hypertension . -
pubmed
Resolution of
oxygen dependency occurred in all
patients but was delayed in the two
patients exhibiting complicating
pulmonary hypertension ( 288.5 + /- 37.4 v 53.5 + /- 35.7 days ) . -
pubmed
This supports the newly implemented United Network for Organ Sharing ( UNOS ) criteria , that LT for
HPS may be extended to include
patients with Pa(
O2 ) & lt ; 60 mm Hg . -
pubmed
We combined PET and magnetic resonance ( MR ) imaging in the planning of SBB in 9
children ( 5
males and 4
females , aged 2 - 14 years ) with infiltrative , ill - defined
brain lesions . -
pubmed
This preliminary series suggests that combining PET and MR imaging in the planning of SBB in
children ( 1 ) improves the diagnostic yield of SBB in infiltrative , ill - defined
brain lesions , ( 2 ) makes it possible to reduce the sampling in high - risk / functional areas and ( 3 ) improves the quality of therapeutic management of pediatric
brain tumors . -
pubmed
Repeated peripheral airway
hyperpnea causes
inflammation and remodeling in
dogs . -
pubmed
We used a
canine model of
hyperpnea with cold , dry air to test the hypothesis that repeated cooling and desiccation of peripheral airways can cause
asthma - like pathology . -
pubmed
Term placentae were collected from non - diabetic subjects and five groups of
diabetic women classified according to duration , severity and
insulin dependence . -
pubmed
Influence of 6 - week exercise training on erythrocyte and liver antioxidant defense in
hyperinsulinemic rats . -
pubmed
High dosage of
fructose in
rats causes
insulin resistance and
hyperinsulinemia . -
pubmed
This study investigates the effect of physical exercise on oxidant - antioxidant balance in
rats fed a high
fructose diet , which show characteristic features of
insulin resistance . -
pubmed
Physical training to these
rats reversed the adverse effects , which could be important in alleviating the pathological consequences of
insulin resistance . -
pubmed
In spite of significant advances in management , mortality in
patients suffering from
heart failure remains unacceptably high and new therapies are urgently needed . -
pubmed
Recently , several large clinical trials have shown a significant reduction in both morbidity and mortality in
heart failure patients when beta - blockers are added to standard therapy . -
pubmed
Needle biopsy of pleura ; an evaluation in
patients with
pleural effusion of neoplastic origin . -
pubmed
Effect of whole - body x - irradiation on the
insulin resistance of fasted
rats . -
pubmed
EFFECTIVENESS OF
CAPREOMYCIN AGAINST
EXPERIMENTAL TUBERCULOSIS OF
MICE AND GUINEA PIGS . -
pubmed
Effects of an acute salt load in a case of primary
hyperaldo - steronism before and nine months after surgical cure : comparison with normal subjects and
patients with
essential hypertension before and after reduction of their elevated pressure with drug treatment . -
pubmed
Viral hepatitis (
VH ) is almost as old as
human beings , at least as old as known
human history . -
pubmed
The mortality figures are projected to show a 2- to 3 - fold increase over the next two decades as
hepatitis C virus - infected patients develop
cirrhosis , which makes this the leading indication for liver transplantation . -
pubmed
The list of hepatotropic viruses is well known , including
hepatitis A (
HAV ) , B (
HBV ) , C (
HCV ) , D (
HDV ) ,
E ( HEV ) , G (
HGV ) and F (
HFV ) . -
pubmed
HGV and
HFV are excluded from the present review , mainly because they are questionable in relation to the causation of
liver disease . -
pubmed
Our knowledge of
HAV ,
HBV ,
HDV and
HEV has accumulated over the last decade , so the present discussion is focused on
HCV , which is currently generating considerable concern and controversy , and is the leading cause of chronic
liver disease worldwide . -
pubmed
Pathologic features of
Crohn ' s disease were present in 4
patients preoperatively and 15 more after repeat ileal pouch - anal anastomosis . -
pubmed
Four
patients had clinical features of
Crohn ' s disease . -
pubmed
Although
pouch failure occurs more frequently than after primary ileal pouch - anal anastomosis ,
patient satisfaction and quality of life are high . -
pubmed
METHODS : A total of 221
patients were studied after resection for
gastric cancer , 110 after D1 surgery and 111 after D3 surgery . -
pubmed
Development of
atrial fibrillation in
patients with
atrioventricular block after atrioventricular synchronized pacing . -
pubmed
Many studies have evidenced an increased incidence of
AF in
patients receiving single chamber ventricular pacing ( VVI ) when compared with those undergoing an atrial - based system ( AAI or DDD ) . -
pubmed
However , the difference in incidence of
AF between two atrial - based systems ( VDD , DDD ) in
patients with
AV block was still controversial . -
pubmed
This study was conducted to compare the development of
AF between different modes of pacemakers ( VDD and DDD ) in
patients with symptomatic
AV block . -
pubmed
A retrospective review was conducted of the detailed records of all consecutive
patients who received permanent pacemakers due to symptomatic
bradycardia from March 1995 to March 2000 . -
pubmed
The
patients were divided into two groups :
VDD ( n = 100 ) and DDD ( n = 52 ) . -
pubmed
The authors suggest that VDD pacing may be a better choice than the DDD system for
patients with
AV block , but without clinical evidence of
sinus node dysfunction , and if an atrial lead is required , it should be placed close to the Bachmann 's bundle . -
pubmed
OBJECTIVE : In
spinal cord injured (
SCI )
subjects , exaggerated withdrawal reflexes associated with a dominant flexor pattern irrespective of stimulation site have been reported . -
pubmed
The reflexes in biceps femoris and vastus lateralis muscles were small and associated with weak knee flexion at all 10 sites in the
SCI subjects and in the controls . -
pubmed
The expansion is most likely due to lack of descending inhibitory control and/or increased sensitivity of the spinal reflex loop in the
SCI subjects . -
pubmed
Noninvasive assessment of
tumor vascularity by contrast - enhanced ultrasonography and the prognosis of
patients with nonresectable
pancreatic carcinoma . -
pubmed
BACKGROUND : Studies have shown that angiogenesis is one of the factors that influences the prognosis of
patients with
solid tumors , including
pancreatic carcinomas . -
pubmed
However , none have assessed noninvasively the relation between angiogenesis and prognosis in
patients with
pancreatic carcinoma . -
pubmed
The objectives of this study were to assess the vascularity of
pancreatic carcinoma noninvasively by contrast - enhanced US and to clarify the prognostic value of
tumor vascularity in
patients with nonresectable
pancreatic carcinoma . -
pubmed
METHODS : Thirty - five consecutive
patients with pathologically confirmed , nonresectable
pancreatic carcinoma were examined with contrast - enhanced US before systemic chemotherapy . -
pubmed
The median survival also was longer in
patients who had avascular
tumors ( 267 days vs. 115 days , respectively ; P=0.0034 ; log - rank test ) . -
pubmed
CONCLUSIONS : The current results indicated that contrast - enhanced US may be useful in assessing the prognosis of
patients with nonresectable
pancreatic carcinoma who receive systemic chemotherapy . -
pubmed
A 35 - year - old Chinese
man presented with acute
thyrotoxic periodic paralysis complicated by near - fatal
cardiac arrhythmias due to persistent
hypokalaemia , despite maximum
potassium supplementation . -
pubmed
In this unusual case of severe refractory
hypokalaemia leading to
ventricular fibrillation in a
patient with underlying
thyrotoxicosis , the potential dangers concerning the use of
dextrose infusion and beta - adrenergic agent for resuscitation are highlighted . -
pubmed
Fifty - one
patients with 73
idiopathic clubfeet were recruited . -
pubmed
The study group consisted of 38 ( 51.3 % )
patients with
acute myocardial infarction (
AMI ) and 36 ( 48.6 % ) with
unstable angina pectoris . -
pubmed
OBJECTIVE : To assess the impact of carotid endarterectomy on blood pressure homeostasis and baroreflex function , with particular reference to the presence or absence of significant contralateral
carotid artery disease , we conducted a prospective study in 80
patients with symptomatic extracranial
carotid disease undergoing carotid endarterectomy in a regional teaching hospital over 2 years . -
pubmed
METHODS :
Patients were divided into two groups : the control group ( n = 37 ) had no significant contralateral
carotid disease ;
patients in the diseased group ( n = 23 ) had either & gt;70 %
stenosis or occlusion of the contralateral carotid artery . -
pubmed
Seventeen
patients with
abnormal heart rhythms , poor quality recordings , or with intermediate degrees of contralateral
carotid stenosis were excluded . -
pubmed
There were significant reductions in baroreflex sensitivity and a
hypertensive shift in the operating set point , the magnitude of which was significantly greater in
patients with contralateral
carotid disease . -
pubmed
Patients with contralateral
carotid stenosis have a reduced baroreflex reserve and show greater baroreflex dysfunction and hemodynamic instability after endarterectomy . -
pubmed
The persistence of isolated
tumor cells in bone marrow from
patients with
breast carcinoma predicts an increased risk for
recurrence . -
pubmed
Gnotobiotic
dogs have been used to study the pathogenesis of
acquired immunodeficiencies associated with canine distemper virus (
CDV ) . -
pubmed
In recent years , the laboratory at OSU , in conjunction with University of Pennsylvania personnel have begun a series of long - term studies of
dogs affected with the
canine X chromosome - linked severe combined immunodeficiency ( XSCID ) syndrome . -
pubmed
XSCIDs dogs , raised within a gnotobiotic environment for up to 3 years remain clinically healthy and are , in every respect normal except for the persistent T - cell defect and the failure to develop lymph nodes . -
pubmed
The number of
olfactory mucosal neoplasms was reduced by 25 % after 1 year of
alachlor treatment in
rats that received both
alachlor and
Ro 28 - 2653 . -
pubmed
Catha edulis also leads to several peripheral effects that include increases in blood pressure and has been associated with the increased incidence of acute
coronary vasospasm and
myocardial infarction . -
pubmed
Catha edulis also accounts for a number of gastrointestinal tract problems ,
oesophagitis ,
gastritis and delay intestinal absorption , as well as the development of
oral keratotic white lesions at the site of chewing . -
pubmed
Administration of
Catha edulis extracts showed a deranged systemic capacity to handle oxidative radicals and induces cytotoxic effects in cells of liver and kidney , as well as induction of cell
death in various
human leukaemia cell lines and in peripheral
human blood leukocytes . -
pubmed
No
death or toxic effects were observed among
animals . -
pubmed
Does abdominal aorta clamping , as a method of
spinal ischemia in
rats , really work ? -
pubmed
Our aim was to highlight both morphological and functional abnormalities in a same group of 10
SD patients , in the entire brain , using a " state of the art " methodology ( optimized VBM procedure , PET data corrected for partial volume effects and voxel - based analyses ) . -
pubmed
We showed that main alterations concerned the left temporal lobe , in accordance with the striking impairment of semantic memory in
SD patients , as well as the hippocampal region , which may partly explain their moderate
episodic memory deficits . -
pubmed
Amelioration of
benzo ( a ) pyrene - induced
lung carcinogenesis in
strain A mice by
diphenylmethyl selenocyanate . -
pubmed
BP was given at a dose of 0.2mg /
mouse to initiate
lung carcinogenesis in
strain A mouse and the
Se compound was given orally at a dose of 3mg / kgb.w . -
pubmed
SSc patients were grouped into 22
patients with limited
cutaneous SSc (
lcSSc ) and 27
patients with diffuse
cutaneous SSc (
dcSSc ) . -
pubmed
Individuals with functional
hypothalamic hypogonadism typically engage in a combination of behaviors that concomitantly heighten psychogenic stress and increase energy demand . -
pubmed
The increasing number of
cancers seen early after transplantation and the increased risk of developing a
cancer due to the older age of recipients draw attention to the importance of regular oncologic screening in
patients on the waiting list and after transplantation . -
pubmed
METHODS : Eightyone
patients who underwent resective extratemporal
epilepsy surgery were retrospectively studied concerning ( a ) age at surgery , ( b ) onset of
epilepsy , ( c ) duration of
epilepsy , ( d ) number of
seizures at the time of presurgical evaluation , ( d ) number of presurgically tested antiepileptic substances and ( f ) number of
seizure types . -
pubmed
RESULTS : 33
patients ( 40.7 % ) were
seizure free two years after surgery . -
pubmed
The
recurrence rate in
patients with one or more
seizures per day was more than two - fold if compared with
patients with fewer
seizures . -
pubmed
The remaining demographic factors did not show a significant association with
seizure outcome in our 81
patients . -
pubmed
OBJECTIVE : To explore the coagulation indexes and offer a valuable reference for clinic therapy and prognosis in
patients with
oral squamous cell carcinomas (
OSCCs ) . -
pubmed
All
patients with
OSCCs were divided into three groups included primary
tumor , neck
metastasis of lymph nodes and
recurrence . -
pubmed
RESULTS : The index of PT in
patients with
OSCCs was longer than that of healthy
people . -
pubmed
CONCLUSION : PT and APTT may be the useful indexes for clinic therapy and prognosis in
patients with
oral squamous cell carcinomas . -
pubmed
A 51 - year - old
man complained of left facial
swelling and recurrent
nasal bleeding . -
pubmed
Combination chemotherapy with
vincristine ,
doxorubicin ,
cyclophosphamide /
ifosfamide with
mesna and
etoposide was administered ; however , the
tumor was unresponsive and the
patient died after around 3 months . -
pubmed
Despite years of intense study by many investigators , it may appear that we have made little progress towards a molecular understanding of
mammalian sperm binding to the egg
zona pellucida . -
pubmed
Nevertheless , a retrospective view of the literature suggests that some common principles are emerging regarding the molecular basis of
mammalian sperm -
zona binding , both with respect to the nature of the components that mediate binding , as well as the involvement of distinct receptor - ligand interactions , that involve both protein- and
carbohydrate - dependent mechanisms of binding . -
pubmed
Traditionally
Boswellia serrata extract is used in the Indian Ayurvedic medicine for the treatment of
inflammatory diseases . -
pubmed
In 2002 the EMEA designated
Boswellia an orphan drug status for the treatment of
peritumoral oedema . -
pubmed
All consecutive
patients younger than 14 years with a first remote symptomatic unprovoked
seizure who were seen at our hospital between 1994 and 2006 were included in the study and prospectively followed . -
pubmed
A total of 55
children out of 63 were affected by a static
encephalopathy of pre- or perinatal origin . -
pubmed
Genomics of
human glioblastoma multiforme : a glimpse of the future . -
pubmed
There is a spectrum of acute illness for individuals who ingest toxigenic
Escherichia coli , ranging from no symptoms to self - limited
gastroenteritis , to full acute
hemolytic uremic syndrome . -
pubmed
PURPOSE :
Bisphosphonate - associated
osteonecrosis of the jaw (
BONJ ) is defined as the presence of exposed bone for at least 8 weeks in
patients with exposure to
bisphosphonates and no history of radiotherapy to the jaw . -
pubmed
We report 5
patients with a history of
bisphosphonate use ,
sinus tracts or deep
periodontal pockets and radiographic findings typical for
BONJ but with no evidence of exposed
necrotic bone at the first evaluation visit . -
pubmed
Patients had multiple
myeloma ( 2 ) ,
multiple myeloma and
prostate cancer ( 1 ) ,
monoclonal gammopathy of unknown significance ( 1 ) and
osteoporosis ( 1 ) . -
pubmed
Subsequently , 4
patients developed exposed bone and 1
patient had
necrotic bone removed from the jaws . -
pubmed
CONCLUSION : We report 5
patients with a history of
bisphosphonate therapy where 4
patients had persistent
sinus tracts and a fifth , severe
bone loss . -
pubmed
Four
patients had radiographic findings typical for
BONJ , and all subsequently developed
necrotic bone . -
pubmed
We propose modifying the definition of
BONJ to include a category of " suspected
BONJ " Stage 0(sa ) where
patients have persistent
sinus tracts or localized deep
periodontal pockets and typical radiographic findings for
BONJ but are asymptomatic , and Stage 0(ss ) for those who are symptomatic . -
pubmed
We disclosed a case of Page kidney associated with subcupsular
renal lymphocele and propose that careful management should be needed in a
patient like our case . -
pubmed
A new model for blunt
liver injuries in the
swine . -
pubmed
BACKGROUND : To elaborate the impact of new haemostatic agents we developed an instrument for the pressure - controlled induction of
blunt liver injuries in a
porcine animal model . -
pubmed
MATERIALS AND METHODS : A dilutional
coagulopathy of 80 % of
animal blood volume was induced in 9 anaesthetized
pigs . -
pubmed
Novel treatment strategies for
patients with
relapsed classical Hodgkin lymphoma . -
pubmed
Although
classical Hodgkin lymphoma (
HL ) is considered one of the most curable
human cancers , the treatment of
patients with relapsed and refractory disease , especially those who relapse after autologous stem cell transplantation , remains challenging . -
pubmed
Patients with
HL whose disease relapses after stem cell transplantation are rarely cured with current treatment modalities . -
pubmed
This review will focus on emerging new treatment modalities that are currently under investigation for
patients with relapsed classical
HL . -
pubmed
We assessed interindividual variability of mean arterial pressure ( MAP ) , CO , and TPR during control conditions in normotensive
humans ( n = 40 ) and during normotension and
deoxycorticosterone acetate - salt
hypertension in
Sprague - Dawley rats ( n = 16 ) . -
pubmed
The
FHC ( fetal
human cells ) cell line has been established from
normal fetal colonic mucosa . -
pubmed
Prostatic disease in the
dog ; clinical manifestations and treatment . -
pubmed
We have 27 files of
patients with
torsion of the spermatic cord confirmed to the intervention . -
pubmed
The
syndrome is frequently misdiagnosed , and
patients receive redundant investigations and treatments . -
pubmed
Patients are referred finally to a neurologist because of the differential diagnosis of
abdominal migraine or
abdominal epilepsy . -
pubmed
CASE REPORT : We present a 18 - year - old
girl with
episodic nausea and vomiting attacks who was diagnosed as
CVS . -
pubmed
Here , we aim to present the clinical features as well as treatment response of a
patient with
CVS . -
pubmed
Experiments on vaccination of
human beings against
epidemic influenza . -
pubmed
Regrettably , in spite of consistent demonstration of a major effect on
pain even in
patients with deeply infiltrating lesions ,
progestins are underestimated and dismissed in favour of more scientifically fashionable and up - to - the - minute alternatives . -
pubmed
Ischemic stroke in young
adults : risk factors , subtypes , and prognosis . -
pubmed
BACKGROUND :
ischemic strokes occurring in
patients younger than 47 years is a relatively rare event and accounts for less than 5 % of all
ischemic strokes in western countries . -
pubmed
METHODS : in this hospital case series study , we enrolled 192
patients with
ischemic stroke , aged 18 to 47 years , all of whom were submitted to a diagnostic protocol . -
pubmed
CONCLUSIONS :
hypertension ,
diabetes mellitus ,
hypercholesterolemia , and smoking were the most common risk factors in our
ischemic stroke patients between 18 - 47 years of age . -
pubmed
PATIENTS AND METHODS : Ten
patients with
metaphyseal radius malunions were treated . -
pubmed
All
patients experienced
wrist pain before surgery , which disappeared or decreased after surgery . -
pubmed
C. Alberti
Prostate carcinoma , even at advanced stages , responds in most
patients to
androgen deprivation therapies , that are able to exploit the
androgen - sensitivity of
prostate cancer cells . -
pubmed
We prospectively included 150
patients who underwent up to four SWL sessions for
renal stones from June 2008 to 2009 . -
pubmed
Patients were evaluated for
stone expulsion ,
colic attacks , amount of analgesics and side - effects of alpha - blockers . -
pubmed
16
patients on
tamsulosin and 21 on
doxazosin experienced adverse effects related to
postural hypotension . -
pubmed
Moreover , 2 ( 4 % )
patients in the
tamsulosin group reported
ejaculatory complaints . -
pubmed
Chrysin protects
mice from
Staphylococcus aureus pneumonia . -
pubmed
aureus
pneumonia through histopathology experiments in a
mouse model . -
pubmed
Over a period of 7 years ( 2003 - 2010 ) , 100 consecutive procedures in 100
patients with
chronic suppurative otitis media were performed at the Mansoura University Hospital ( Egypt ) with a minimum follow - up of 12 months ( range 12 - 72 months ) . -
pubmed
Does carpal tunnel release provide long - term relief in
patients with hemodialysis - associated
carpal tunnel syndrome ? -
pubmed
BACKGROUND :
Carpal tunnel syndrome (
CTS ) is a common complication in
patients receiving long - term hemodialysis . -
pubmed
In the short - term however , these
patients are less likely to have
pain relief and restoration of function after carpal tunnel release . -
pubmed
However , it is unclear whether
patients who have release for hemodialysis - associated
CTS have differing persisting relief of symptoms compared with
patients with
idiopathic CTS . -
pubmed
QUESTIONS / PURPOSES : We therefore compared ( 1 ) the severity of
pain and level of function in
patients who had release for hemodialysis - associated CTS with scores of
patients who had release for idiopathic
CTS , and ( 2 ) the operation - related complications . -
pubmed
METHODS : We retrospectively reviewed 36
patients with
CTS who were receiving hemodialysis and 54
patients with
idiopathic CTS . -
pubmed
Four
patients had complications , all with hemodialysis - associated
CTS : two had revision carpal tunnel releases and two had delayed
wound healing . -
pubmed
CONCLUSIONS :
Patients with hemodialysis - associated
CTS seem to remain impaired , unlike
patients with idiopathic
CTS , but the majority of them might have much improved CTS - related symptoms at 2 years after carpal tunnel release . -
pubmed
Chronic
Chagas disease with
cardiodigestive involvement and the TcVI infective form of
Trypanosoma cruzi . -
pubmed
We report a patient with
megacolon associated with TcVI infective lineage form of
Trypanosoma cruzi . -
pubmed
Individuals with
cocaine dependence often evidence poor cognitive control . -
pubmed
Longitudinal changes in functional disability in
Alzheimer ' s disease patients . -
pubmed
Participants were evaluated using the Mini - Mental Status Exam ( MMSE ) and the Disability Assessment for
Dementia (
DAD ) every six months for < = 2 years . -
pubmed
METHODS : We retrospectively studied 55
patients with early
HCC ( total 99 nodules ) who underwent initial hepatectomy between 1995 and 2010 . -
pubmed
The 5 - year disease - free survival rate was significantly lower in
patients with
GPC3 - positive early
HCC ( 27 % ) than in patients with
GPC3 - negative early
HCC ( 62 % , P = 0.0036 ) . -
pubmed
SUMMARY : Strategies aimed at modifying risk factors for
ischemic optic neuropathy associated with prone spinal fusion surgery that are extrinsic to the
patient may decrease its incidence . -
pubmed
Progression of
glomerular filtration rate reduction determined in conscious Dahl salt - sensitive
hypertensive rats . -
pubmed
Sequential changes in
glomerular filtration rate during development of
hypertension in the conscious Dahl salt - sensitive
rats were determined using a new method for measurement . -
pubmed
We conclude that the observed reduction of
glomerular filtration rate was a consequence and not a cause of the
hypertension and that this noninvasive approach could be used in these conscious Dahl salt - sensitive
rats for a longitudinal assessment of renal function . -
pubmed
OBJECTIVE : Validate a model of high - fat diet - induced
obesity , of low cost , easy reproducibility , that could express characteristics observed in
human , and would enable subsequent therapy proposals . -
pubmed
The most common specific indication was evaluation of facet joint
pain in 70/191 ( 37 % )
patients , and the most common finding was facet joint activity in 106/212 ( 50 % )
patients . -
pubmed
It helps identify several potential
pain generators , is often used in patients who have a near - contemporaneous MRI , and has an impact on the procedural and/or conservative management in most
patients . -
pubmed
Altered invariant natural killer T cell subsets and its functions in
patients with
oral squamous cell carcinoma . -
pubmed
However , iNKT cells are not well characterized in
patients with
oral squamous cell carcinoma (
OSCC ) . -
pubmed
It appears that the selectively enriched iNKT subsets and modulation of their function by specific ligand / agonist may be useful for cellular therapy in
patients with
OSCC . -
pubmed
Further , reduced levels of iNKT cells and its DN subset may be used as potential prognostic factors for
patients with
OSCC . -
pubmed
BACKGROUND : This study retrospectively investigated nutritional status , dietetic intervention and intake in
Cystic Fibrosis (
CF )
patients before and after lung transplantation ( LTX ) . -
pubmed
Patients maintained a low
body weight before LTX . -
pubmed
Intubation difficulties in a
patient with an esophageal
foreign body . -
pubmed
But they were irrelevant with
tumor size ,
patients ' age and gender ( P>0.05 ) . -
pubmed
METHODS : Thirty - two
patients with
MS were included in a monocentric cohort study . -
pubmed
Rebound was associated with severe recurring
relapses in 9 % of the
patients . -
pubmed
Direct deroofing of the lingual
cyst and
plication of the epiglottis were performed at 3 months of age , and the
patient recovered from the
respiratory distress . -
pubmed
METHODS : The study included 130
patients with
RA and 80 healthy controls . -
pubmed
PURPOSE : To evaluate the prognosis of " strict " high - risk nodules ( small hepatocellular nodules detected only in the hepatobiliary phase of initial
Gd - EOB - DTPA - enhanced MR examination ) in
patients with
cirrhosis or
chronic hepatitis . -
pubmed
Taken together , RTL1000 protects against
acute injury if applied within a 6 - h time window and improves long - term functional recovery after experimental
stroke in DR2 - Tg
mice . -
pubmed
Sofosbuvir ,
simeprevir , and
ribavirin for the treatment of
hepatitis C virus recurrence in
human immunodeficiency virus / hepatitis C virus - coinfected liver transplant recipients . -
pubmed
Together , our results demonstrate that protracted subversion of immune dynamics contributes to early dissemination and progression of t(14;18)(+ ) precursors and shapes the systemic presentation of
FL patients . -
pubmed
A total of 90
HD patients were randomly allocated to two 45 - patient groups of oral and video education programs , respectively . -
pubmed
Therefore , video education as an effective , inexpensive , simple , and attractive method is recommended for
HD patients . -
pubmed
We here explored the therapeutic potential of
dexamethasone (
Dex)-loaded liposomes for
inflammatory liver diseases , using experimental models of acute and
chronic liver injury in
mice . -
pubmed
A total of 102
patients , with a mean age of 54.86 + -13.02 years ( range , 30 - 89 years ) , were included in this study and the incidence of
seroma was found to be 22.55 % . -
pubmed
Although surgical removal of the primary
tumor is considered to be curative , the 5 - year survival rate is no more than 20 % even in
patients with clear
resection margins ( R0 ) . -
pubmed
Cancer metastasis is the primary cause of mortality in
cancer patients and is classically viewed as a late event during the progression of the
disease , which is supported by the genetic studies used to understand the evolution of
pancreatic cancer . -
pubmed
In this review , we will discuss the current views regarding
pancreatic cancer metastasis with particular emphasis on the epithelial to mesenchymal transition , its influence on the selection of
patients for surgical resection and the therapeutic intervention . -
pubmed
Neuro - ophthalmological findings in
patients with
acquired prosopagnosia . -
pubmed
Here , we report a spontaneous recessive
mouse mutation that causes progressive cerebellar granule cell
death and peripheral motor
axon degeneration . -
pubmed
MATERIALS AND METHODS : 33
strains of
Vibrio cholerae eltor O1 and
V. - pubmed
Cucumber (
Cucumis sativus L. ) possesses unique attributes useful for organellar genetics , including differential transmission of the three plant genomes ( maternal for plastid , paternal for mitochondrial , and bi - parental for nuclear ) , a relatively large mitochondrial DNA in which recombination among repetitive motifs produces rearrangements , and the existence of strongly mosaic (
MSC ) paternally transmitted phenotypes that appear after passage of wild - type plants through cell cultures and possess unique rearrangements in the mitochondrial DNA . -
pubmed
METHODS : Ten embalmed
human cadavers were selected . -
pubmed
Long non - coding RNAs ( lncRNAs ) are emerging as key molecules in
human cancer genesis and progression , including
prostate cancer . -
pubmed
METHOD : This retrospective study includes 70
patients with
SOM who underwent surgery between 1995 and 2012 . -
pubmed
In addition , 14 % of
patients experienced persistent
pain at the location of the iliac harvesting site . -
pubmed
Hippocampal
neuronal degeneration in the
traumatic brain injury mouse : non - trivial effect of scalp incision . -
pubmed
OBJECTIVES : In experimental models of
traumatic brain injury (
TBI ) , posttraumatic hippocampal
neuronal degeneration in the cornu ammonis 1 ( CA1 ) , and/or the cornu ammonis 3 ( CA3 ) regions are regarded as the most notable phenotypic appearances relating to the pathophysiology of
human post - concussion syndrome . -
pubmed
The frequencies and reasons of appearance of hippocampal
neuronal degeneration in
mice with
TBI and/or sham are not clear . -
pubmed
METHODS : We compared the frequencies of hippocampal
neuronal degeneration among three groups :
TBI (
mice with external force impact performed by Marmarou 's weight drop model after scalp incision ) , sham (
mice with scalp incision alone ) , and control (
mice with neither external force impact nor scalp incision ) , using
hematoxylin and eosin stain in day 6 ( n = 5 in each group . ) -
pubmed
Careful interpretation is needed concerning hippocampal
neuronal degeneration induced by a weight drop device observed in
mice with
TBI . -
pubmed
2,3,7,8 - Tetrachlorodibenzo - p - dioxin (
TCDD ) increases
necroinflammation and hepatic stellate cell activation but does not exacerbate experimental
liver fibrosis in
mice . -
pubmed
The goal of this study was to determine how
TCDD impacts HSC activation in vivo using a
mouse model of experimental
liver fibrosis . -
pubmed
To elicit
fibrosis , C57BL6 / male
mice were treated twice weekly for 8weeks with 0.5ml / kg
carbon tetrachloride (
CCl4 ) . -
pubmed
PATIENTS AND METHODS : A retrospective review of medical records of
patients with
orbital cellulitis from January 2008 to December 2014 was conducted . -
pubmed
Orbital
cellulitis was a unilateral occurrence in 38 ( 90.5 % )
patients . -
pubmed
Trauma and
sinusitis were the common predisposing causes in 20 ( 47.6 % ) and 6 ( 14.3 % )
patients , respectively . -
pubmed
Postmortem tissue from 79
individuals was evaluated , including cognitively intact " young "
individuals aged younger than 60 years ( range , 33 - 57 years ) , cognitively intact " aged "
individuals aged older than 60 years ( range , 61 - 96 years ) with no known
neurological disease , and
individuals older than 60 years ( range , 61 - 105 years ) of age with a clinical history of
AD confirmed by histopathological evaluation . -
pubmed
Forty - eight
patient samples ( 10 young , 20 aged , and 18 with
AD ) underwent histological analysis . -
pubmed
Sixty
patient samples underwent Western blot analysis ( 15 young , 24 aged , and 21 with
AD ) . -
pubmed
Objective of this study is to assess the kind and the effectiveness of the most suitable treatment in the
apophyseal and epiphyseal knee lesions occurring in the
adolescents . -
pubmed
MATERIALS AND METHODS : From 2006 to 2011 , were treated 41
patients ( 34 M-7 F ) between the ages of 10 and 15 , with a diagnosis of traumatic
knee injury caused by sports activities . -
pubmed
METHODS : Regularly cycling
women and
men without
obesity underwent a crossover 6 - hour infusion study over four visits . -
pubmed
Rat islets exhibit active transport of
MI , although the mechanism involved remains elusive . -
pubmed
In corroboration , chronic
MI treatment improved the disease phenotypes of
diabetic rats and islets . -
pubmed
Children with
cerebral palsy may have raised lead levels , further impairing their residual cognitive motor and behavioral abilities . -
pubmed
Aims and Objectives : To measure blood lead levels in
children with
cerebral palsy and compare them with healthy neurologically normal
children . -
pubmed
Participants : Cases comprised 34
children with
cerebral palsy , and controls comprised 34 neurologically normal , age- and sex - matched children . -
pubmed
Among
children with
cerebral palsy , 19 ( 55.88 % )
children had blood lead levels & gt;=5 microg / dL. -
pubmed
Lead levels in
children with
pica were 12.33 + - 10.02 microg / dL in comparison to children with no history of
pica , 6.70 + - 4.60 microg / dL ( P = .029 ) . -
pubmed
Conclusion : In our study , blood lead levels are raised in
children with
cerebral palsy . -
pubmed
METHODS : Nine
patients with untreated , biopsy - proven large hepatic
metastases ( minimum diameter of 3 cm ) were included . -
pubmed
Genome Sequences of Three Novel Isolates of
Human Parainfluenza Virus 2 Associated with
Acute Respiratory Infection . -
pubmed
This information should be helpful to physicians in the treatment of
LBP patients . -
pubmed
Re : Low - Intensity Shockwave Therapy Improves Hemodynamic Parameters in
Patients with
Vasculogenic Erectile Dysfunction : A Triplex Ultrasonography - Based Sham - Controlled Trial . -
pubmed
Methods : A retrospective chart review between January 1 , 2008 and October 30 , 2015 of
patients with biopsy - confirmed lymphocytic , collagenous , or microscopic
colitis was conducted . -
pubmed
Symptom exacerbations were documented during therapy for 19 % of
patients ; therapy changes resulted in good response . -
pubmed
Determination of
dehydroepiandrosterone and its biologically active oxygenated metabolites in
human plasma evinces a hormonal imbalance during
HIV - TB coinfection . -
pubmed
To our knowledge , this represents the first report of their simultaneous measurement in
HIV - TB individuals and the comparison with healthy donors , obtaining statistically higher plasma levels of
DHEA ,
AET and
7 - oxo - DHEA in
patients . -
pubmed
Between June 2015 and December 2016 , a total of 1268
AHA cases were documented , and 601 cases ( 47.4 % ) were co - infected with
HIV ; the majority of whom were MSM ( 98.4 % ) . -
pubmed
Each AHA case was matched to two
HIV - infected controls without
AHA reported in the NDSS on age ( + - 5 years ) , risk factor of
HIV infection ,
HIV diagnosis date ( + - 30 days ) and county / city of residence at
HIV diagnosis . -
pubmed
Three hundred forty - three
HIV /
AHA cases were matched to 686 controls . -
pubmed
HIV /
AHA cases were centralized in northern and central metropolitan areas and
HIV - infected MSM with a recent history of
sexually transmitted diseases in Taiwan . -
pubmed
We recommend surveillance of associated behavioural and virologic characteristics and
HAV counselling and testing for
HIV - infected men . -
pubmed
Omega-3 supplementation effects on
body weight and
depression among dieter
women with co - morbidity of
depression and
obesity compared with the placebo : A randomized clinical trial . -
pubmed
PURPOSE : We aimed to evaluate the effects of the omega-3 supplementation on
body weight and
depression among
women with co - morbidity of
depression and
obesity seeking
weight reduction compared with the placebo . -
pubmed
METHODS : Sixty five
patients with co - morbidity of
depression and
overweight /
obesity (
BMI & gt;= 25 ) signed the informed consent form and enrolled into this 12 - week double - blind , placebo - controlled randomized clinical Trial . -
pubmed
CONCLUSION : Based on our findings omega-3 capsule as a safe over - the - counter supplement might be helpful in reducing the signs of
depression and also
body weight in
patients with co - morbidity of
depression and
obesity . -
pubmed
The article presents an algorithm for prevention and emergency care for a
patient with dental needle
fracture during mandibular block . -
pubmed
METHODS : For this study , 213 nulliparous
women who planned vaginal delivery were enrolled and assessed daily until they completed three outcomes : ( 1 )
pain resolution ; ( 2 ) opioid cessation ; and ( 3 ) self - assessed functional recovery to predelivery level . -
pubmed
Complexes
Ir1 - Ir5 acted as in vitro photodynamic therapy ( PDT ) agents toward
human SK - MEL-28 melanoma cells when activated with visible light , with submicromolar photocytotoxicity and phototherapeutic indices ranging from 20 to almost 300 . -
pubmed
METHODS : This is a retrospective cohort study of all lung transplant
recipients who developed
airway stenosis and who were treated with
MMC over 4 years . -
pubmed
RESULTS : Eleven lung transplant
recipients , with
airway stenosis were included in our study , who required recurrent
balloon dilation , despite airway stents in place in 73 % of these
patients . -
pubmed
The primary goal of
HCV therapy is the long - term elimination of
HCV from the blood to reduce the risk of
HCV associated complications and
death . -
pubmed
OBJECTIVE : The purpose of this article is to review the most commonly used
tumor markers in
abdominal and pelvic tumors , describe their limitations and explain how to use them in the context of known
cancer in order to optimize multidisciplinary care of oncologic
patients . -
pubmed
However , radiologists should also be aware of the limitations of the most commonly used
tumor markers and they should not be used solely , but interpreted in conjunction with diagnostic imaging , clinical history and physical examination that will help optimize the multidisciplinary care and management of oncologic
patients . -
pubmed
This particulate
breast cancer vaccine was prepared by spray drying technique and utilized
murine breast cancer whole cell lysate as a source of
tumor - associated antigens . -
pubmed
Upon challenge with live
murine breast cancer cells , the vaccinated animals showed five times more
tumor suppression than the control animals confirming the immune response activation and protection ( p & lt ; 0.001 ) . -
pubmed
However , up to 30 % of
patients suffer from
relapses despite complete B cell depletion . -
pubmed
Our data suggest that early escalation of therapy with
tocilizumab may lead to stabilization of disease activity in pediatric
NMOSD patients who relapse under B cell depletion . -
pubmed
Sepsis and
AKI were induced by infusion of live
Escherichia coli . -
pubmed
The risks are especially high for orphans and unaccompanied children who are separated from their families , making them frequently victims of
human trafficking , slavery ,
drug addiction , crime or sexual exploitation . -
pubmed
The effects of cognitive reserve on predicting and moderating the cognitive and psychosocial functioning of
patients with
bipolar disorder . -
pubmed
METHODS : One hundred and twenty - five
outpatients with
BD type I and sixty healthy
individuals were recruited . -
pubmed
All
participants were assessed with a neuropsychological battery examining attention and processing speed , working memory , visual memory and executive functioning , the Global Assessment of Functioning scale and the Cognitive Complaints in
Bipolar Disorder Rating Assessment . -
pubmed
RESULTS :
Patients with
bipolar disorder presented with worse cognitive performance and psychosocial functioning than healthy controls . -
pubmed
METHODS : We report for the case of a 10 - year - old male
patient who was diagnosed with
Cavernous Angioma in Posterior Sagittal Sinus . -
pubmed
This study aimed to clarify the clinical significance of TEVAR in
esophageal cancer patients . -
pubmed
RESULTS : Of the 41
patients identified , 20 patients underwent TEVAR for
hemorrhage or impending
hemorrhage from the esophagoaortic
fistula , while 21
patients underwent TEVAR as preoperative prophylaxis . -
pubmed
CONCLUSION : TEVAR is an efficacious modality to control a life - threatening
hemorrhage from
esophagoaortic fistula and helps to prolong the survival of
patients with locally advanced
esophageal cancer invading the aorta . -
pubmed
These genes were overexpressed in
Escherichia coli strains previously engineered to produce different carotenoids . -
pubmed
Maximum
tumor diameter is associated with event - free survival in PET - negative
patients with
stage I / IIA Hodgkin lymphoma . -
pubmed
METHODS : We retrospectively identified and reviewed the charts of 31
patients with
intraparenchymal brain metastases from
prostate adenocarcinoma seen at our institution from 2008 to 2018 . -
pubmed
RESULTS : Among all
patients with
brain metastases , the proportion originating from
prostate adenocarcinoma was 0.86 % . -
pubmed
Patients had concurrent
metastases to bone ( 100 % ) , lung ( 48 % ) , and liver ( 35 % ) . -
pubmed
All
patients died of advanced , systemic disease and not of their
intracranial disease . -
pubmed
These data enable treating physicians to appropriately counsel their
patients with
prostate adenocarcinoma brain metastasis . -
pubmed
The author reports a retrospective personal series of
patients managed over a seven - year period with a nearly unchanged surgical strategy implementing most of known measures for
capsular contracture prevention . -
pubmed
Of the
patients in the revision cohort , 44.3 % were reoperated on because of previous
capsular contracture . -
pubmed
Toxicity ( > = grade 3 ) in 85 evaluable
patients included
hypertension ( n=37 ) , neurological changes ( n=2 ) ,
anorexia ( n=2 ) ,
infections ( n=9 ) ,
wound dehiscence ( n=2 ) ,
DVT /
PE ( n=2 ) , and
colonic perforation ( n=1 ) . -
pubmed
CONCLUSIONS :
Bevacizumab combined with
vorinostat did not yield improvement in PFS , OS or clinical benefit compared with
bevacizumab alone nor a clinical benefit in
adults with recurrent
GBM . -
pubmed
This trial is the first to test a Bayesian adaptive design with adaptive randomization and Bayesian continuous monitoring in
patients with primary
brain tumor and demonstrates the feasibility of using complex Bayesian adaptive design in a multicenter setting . -
pubmed
Structural Changes in the Lungs and Liver of
Mice with Experimental
Tuberculosis Treated with Liposome - Encapsulated
Dextrazide . -
pubmed
Efficacy of a
foot - and - mouth disease vaccine against a heterologous SAT1 virus challenge in
goats . -
pubmed
Goats are susceptible to
infection with foot - and - mouth disease virus (
FMDV ) , but their role in the epidemiology of the disease and response to vaccination is poorly understood . -
pubmed
In this study , we evaluated the efficacy of a pentavalent
FMD vaccine in
goats against heterologous challenge with a pool of field SAT1
FMDV . -
pubmed
OBJECTIVES : As
Chlamydia trachomatis (
CT ) and
Neisseria gonorrhoeae (
NG ) are the most commonly reported
STIs in Belgium and the majority of women infected are asymptomatic , targeted screening of patients in specified risk groups is indicated . -
pubmed
Cadophora luteo - olivacea is the most prevalent Cadophora species associated with
Petri disease and esca of grapevine . -
pubmed
A neuropsychologically - based intervention with increased follow - up support for employed
women with
multiple sclerosis : a pilot randomized controlled trial . -
pubmed
OBJECTIVE : To evaluate feasibility and acceptability of a neuropsychologically - based vocational intervention with increased follow - up support for
women with
multiple sclerosis . -
pubmed
PARTICIPANTS : Forty - nine employed
women with
multiple sclerosis meeting criteria on measures of
cognitive dysfunction ( Symbol Digit Modalities Test ) ,
fatigue (
Fatigue Severity Scale ) , and/or
depression ( Beck Depression Inventory / Patient Health Questionnaire ) . -
pubmed
Prevention of
DoxDHCer accumulation in
worms and in
mouse hearts resulted in decreased
anoxia - induced
injury . -
pubmed
MATERIALS AND METHODS : Twenty - eight
males with
obesity were randomly allocated to an experimental group ( EG , n=14 ) or a control group ( CG , n=14 ) . -
pubmed
BACKGROUND : Our
Cystic Fibrosis (
CF ) Center initiated a Quality Improvement ( QI ) project in November 2017 with the goal of improving our
patients ' Forced Expiratory Volume in One Second ( FEV1 ) percent predicted ( pp ) and continued for 1 year . -
pubmed
Our specific aim was to increase the relative mean FEV1 pp by 5 % in 12 months for
CF patients 6 - 21 years old with FEV1 < = 80 pp . -
pubmed
Fluorescent NPs have great potentials in targeted theranostics including
cancer imaging , immunoassay based cells , proteins and
bacteria detections , imaging - guided surgery and therapy . -
pubmed
MATERIAL AND METHODS :
Patients with severely
atrophic maxillae were classified into two groups according to the use of CBCT- or MSCT - guided navigation system . -
pubmed
Colistin - induced
nephrotoxicity occurred in 45.71 % of the
patients , of whom 40.6 % were at Risk , 21.9 % at
Injury , and 37.5 % at Failure according to RIFLE criteria . -
pubmed
In
patients who developed
AKI , the average total
colistin dose received before
AKI was 4.4 mg / kg / day . -
pubmed
Streptococcus gordonii infectious endocarditis presenting as a
neurocysticercosis mimic - A rare manifestation . -
pubmed
For
patient diagnosed as
neurocysticercosis , clinical follow - up is recommended and presence of systemic symptoms should be red flags for another underlying disease . -
pubmed
Better molecular characterization of the disease has led to the rapid improvement of personalized medicine and the prompt delivery of targeted therapies to
patients with
NSCLC . -
pubmed
Additionally , the results of ongoing clinical trials with novel - generation TKI will provide more evidence on the best sequence in the treatment of
ALK - positive NSCLC patients . -
pubmed
Provitamin A - biofortified
maize could contribute to the alleviation of
vitamin A deficiency ( VAD ) , which is prevalent in sub - Saharan Africa due to a high consumption of starchy ,
maize - based diets . -
pubmed
Autopsy Proven
Pulmonary Mucormycosis Due to
Rhizopus microsporus in a Critically Ill COVID-19 Patient with Underlying
Hematological Malignancy . -
pubmed
Effect of various protein diets on growth , renal function , and survival of
uremic rats . -
pubmed
In controls fed ad lib , weight and length gain were better with high protein diets , whereas they were inversely related to the diet protein content in
uremic rats . -
pubmed
We report the case of a young female
patient who developed an acute
polyradiculoneuropathy when she recommended intravenous
heroin after four years abstinence . -
pubmed
Lower limit of cerebral blood flow autoregulation in experimental
renovascular hypertension in the
baboon . -
pubmed
The effect of chronic
renovascular hypertension on the autoregulation of cerebral blood flow was studied in anesthetized
baboons . -
pubmed
Six
baboons with
renal hypertension of 8 - 12 weeks ' duration were compared with six normotensive controls . -
pubmed
In the chronically
hypertensive baboons cerebral blood flow autoregulated until the mean arterial pressure had decreased to the range of 75 - 89 mm Hg . -
pubmed
Therefore , the lower limit of autoregulation of cerebral blood flow was shifted to higher absolute levels of mean arterial pressure in
baboons with chronic
renovascular hypertension presumably due to adaptive changes in the cerebral circulation . -
pubmed
Unexplained
pelvic distress or
pain was observed in the 4 patients of this report ( 3 women and 1
man ) , and also in 6 other patients during a 10 - year period of neurologic practice . -
pubmed
It is suggested that this may be a valid entity and that , as with
trigeminal neuralgia and
postherpetic neuralgia , it is truly limited to aged
patients . -
pubmed
It may be possible in the future to develop strategies for
patients with
GI cancers that will be based upon hormonal manipulation in a manner similar to current strategies that are at present employed in the treatment of
patients with
breast cancer . -
pubmed
Recently , it was suggested that the role of
hyperinsulinemia on the
hypertensive mechanism of essential
hypertension might be related to renal
sodium handling and sympathetic nerve activity , especially in obese
hypertensive patients . -
pubmed
Molecular hybridization with cloned fragments of
tick - borne encephalitis ( TBE ) virus cDNA in acute and chronic
TBE infection . -
pubmed
Recombinant plasmid DNA was used as a probe to detect
tick - borne encephalitis ( TBE ) virus RNA during incubation period ,
acute disease and persistent
infection of
syrian hamsters . -
pubmed
In addition , electron microscopic findings in
hamster brain confirmed the hypothesis that
TBE virus persistence was accompanied by formation of virus - specific structures but impaired virion maturation . -
pubmed
This multicenter trial had a sample size goal of 2,220
patients between 21 and 79 years of age who had recently sustained a
myocardial infarction and who have an ejection fraction determined by radionuclide ventriculogram ( RVG - EF ) of less than or equal to 40 % . -
pubmed
In addition to conventional therapy ,
patients were randomly assigned to
captopril or placebo therapy commencing within 3 - 16 days following their
myocardial infarction . -
pubmed
Ten
patients requiring a cardioverter - defibrillator for recurrent sustained
ventricular tachycardia ( five
patients ) or aborted
sudden cardiac death ( five
patients ) were evaluated for implantation of this lead system . -
pubmed
In 10 open - chest
dogs on cardiopulmonary bypass , the hearts underwent 30 minutes of normothermic global
ischemia followed by one hour of multidose hypothermic ( 4 degrees C ) ,
hypocalcemic ( 0.3 mmol / L ) blood cardioplegia . -
pubmed
Here we demonstrate that a high proportion of sperm obtained from certain
strains of + /t
mice undergo a premature acrosome reaction under in vitro capacitation conditions . -
pubmed
They show no phenotypic correlates of
malignancy in vitro and produce
tumors in syngeneic
Fischer rats after long latency periods . -
pubmed
In
patients with
coronary disease , we are used to observe a wide variety of ST segment , T wave and sometimes U wave abnormalities . -
pubmed
The data on anatomical connections ,
injury consequences , summate and unit activity records may be represented as a chain of events running in sequence and in parallel in the brain of higher
mammals . -
pubmed
Development in normal and
hypothyroid animals . -
pubmed
All the nervous structures of the cochlea were , however , stained at the end of the first postnatal month , as in normal
animals , despite the irreversible complete
deafness . -
pubmed
Combined
chronic toxicity and
carcinogenicity studies of
morpholine oleic acid salt in
B6C3F1 mice . -
pubmed
The male
mice given 0.25 %
MOAS had a significantly reduced incidence of
hepatocellular carcinoma in comparison with the control group and this trend was indicated also in the 1.0 % group . -
pubmed
Although high concentrations were found in many
patients with
GU ( P less than 0.01 ) , similar concentrations were found in many
patients with radiologically non - functioning gallbladders containing
gallstones (
NFG ) ( P less than 0.01 ) and also after cholecystectomy ( AC ) ( P less than 0.01 ) . -
pubmed
Since
patients with
cholelithiasis or after cholecystectomy are not known to have an increased incidence of
gastric ulceration , the significance of
duodenogastric reflux in the aetiology of
gastric ulcers must be questioned . -
pubmed
[ Therapeutic effect of lipids from the Far
Eastern sardine (
Sardinops sagax melanostica ) in experimental
hypercholesterolemia in
rats ] . -
pubmed
Hypercholesterolemia was experimentally induced in
rats which received diets with a high fat content ( 66 % calories ) and
cholesterol loading ( 2.5 % of ration ) . -
pubmed
Our study was carried out to clarify the changes in granulocyte functions and circulating immune complexes in 32
children with
Kawasaki disease . -
pubmed
Patients were divided into two groups , those with or without
coronary aneurysm . -
pubmed
[ Comparison of
cardiomegalies developing during different periods in the postnatal development of the
rat -- various morphological and biochemical parameters ] . -
pubmed
Nursing care of
patients with
cancer of the head and neck . -
pubmed
Progesterone synthesis in the pure trophoblasts of
human choriocarcinoma . -
pubmed
An acute low oral dose ( 2 mg ) of
bromocriptine was administered in a randomized double blind fashion to 11 chronic symptomatic mediated
schizophrenic patients . -
pubmed
These results suggest a need for further replication in a larger study population and a need for controlled studies with chronic administration of low dose
bromocriptine in chronic medicated
schizophrenic patients . -
pubmed
Reflex cardiovascular responses to chemoreceptor stimulation in conscious
dogs with
cardiac hypertrophy . -
pubmed
When respiration was controlled to eliminate pulmonary inflation reflex activation , the late
CCRA - induced increase ( P less than 0.01 ) in right coronary resistance was still found to be depressed ( P less than 0.01 ) in the RV
hypertrophy group ( 1.11 + /- 0.20 mmHg X ml-1 X min ) compared with normal
dogs ( 3.65 + /- 0.75 ) . -
pubmed
In contrast to the depressed right coronary vasoconstriction , the
CCRA - induced alpha - adrenergic constriction ( P less than 0.01 ) of the iliac arterial vascular bed was similar in both groups , and the cholinergic increase ( P less than 0.01 ) in cardiac cycle length was enhanced ( P less than 0.01 ) in the RV
hypertrophy group compared with normal
dogs.(ABSTRACT TRUNCATED AT 250 WORDS ) -
pubmed
Effects of
aminoglutethimide on
delta 5 - androstenediol metabolism in postmenopausal
women with
breast cancer . -
pubmed
Aminoglutethimide plus
hydrocortisone ( " medical adrenalectomy " ) has been used to treat postmenopausal
women with metastatic
breast cancer . -
pubmed
We studied
delta 5 - androstene-3 beta , 17 beta - diol metabolism in postmenopausal
women with
breast cancer before and during
aminoglutethimide - plus -
hydrocortisone therapy , utilizing the constant infusion technique . -
pubmed
Neutron and neutron - boost irradiation of
soft tissue sarcomas : a 4.5 year analysis of 139
patients . -
pubmed
A 4.5 year analysis of neutron and neutron - boost therapy is presented for 139
patients with
soft tissue sarcomas . -
pubmed
Advanced
renal failure in
patients with
sickle cell anemia : clinical course and prognosis . -
pubmed
Advanced
renal failure occurred in nine adult
sickle cell disease patients . -
pubmed
Eight
patients had homozygous
SS disease , one had
sickle cell thalassemia . -
pubmed
Angina pectoris ,
hyperkalemia , and severe
anemia complicated chronic dialysis , suggesting that early transplantation should be considered for
sickle cell anemia patients with
renal failure . -
pubmed
The clinical and radiological features of five
patients with
renal hydatid disease communicating with the collecting system are described . -
pubmed
Haemodynamic effects of
calcium chloride administered intravenously to
patients with and without
cardiac disease during neurolept anaesthesia . -
pubmed
No good correlation existed between the inhibition of
bone resorption measured in vitro on calvaria and that seen in vivo on
rat tibiae metaphyses . -
pubmed
Perfused
rat hindlimb
wound model : lambda - carrageenan induced . -
pubmed
We established an isolated perfused
rat hindlimb
wound model using intramuscular injections of lambda - carrageenan . -
pubmed
Wound and control hindlimbs of 24 - h fasting anesthetized (
phenobarbital sodium , 5 mg/100 g body wt )
rats were perfused for 60 min ( 10 ml / min ) with media containing 10 mM
glucose and physiological levels of
amino acids . -
pubmed
From 1968 to January 1 , 1977 , 44
patients with initially unresectable colorectal
carcinoma were treated with preoperative radiotherapy and surgery . -
pubmed
Although prospective studies of defibrillator
shock overdose can not be performed in
man , the therapeutic indices of various defibrillating current waveforms can be measured in animals . -
pubmed
We determined the ratios TD50 / ED50 and LD50 / ED50 ( where TD50 = median " toxic " or damage - inducing dose , ED50 = median effective or defibrillating dose , and LD50 = median lethal dose ) as measures of the therapeutic index for damped sine wave defibrillator
shocks in
dogs . -
pubmed
These data indicate a reasonable margin of safety for damped sine wave defibrillator
shocks in
dogs , and are consistent with reported incidences of suspected
shock - induced damage in
humans . -
pubmed
Dichloroacetylene (
DCA ) shows pronounced
nephrotoxic effects in several
animal species and is
neurotoxic in
humans . -
pubmed
METHODS : We tested this
tumor marker in 35
patients of
gastric cancer , 13
patients of
hepatoma , 13
patients of
colon cancer , 8
patients of
lung cancer , and 22
patients without
malignancy ( 4 of
acute pancreatitis , 10 of benign
gastric ulcer and 8 normal subjects ) between July and December 1991 . -
pubmed
Six
tumor markers were assessed at the same time in 32
patients of
gastric cancer . -
pubmed
The purpose of our study was to determine the biological effect of
selenium on growth of
rat glioma and
human glioblastoma cell lines . -
pubmed
An antiproliferative effect of
selenium was found in two cell lines , which was more effective on
human A172 glioblastoma and less effective on
rat C6 glioma . -
pubmed
An ongoing phase I / II trial in
patients with chemotherapy - naive metastatic
breast cancer ( one adjuvant chemotherapy regimen is allowed ) uses a 3 - hour infusion of
paclitaxel (
Taxol ; Bristol - Myers Squibb Company , Princeton , NJ ) 90 mg / m2 followed by a 3 - hour infusion of
cisplatin 60 mg / m2 every 2 weeks given with standard premedications . -
pubmed
Eighteen
patients are evaluable for
toxicity . -
pubmed
In order to develop a rapid method for the diagnosis of
human brucellosis , results of the ELISA test performed on dried whole blood spotted on filter paper were compared with those of the same test carried out on the serum of the same 160 subjects . -
pubmed
Identification of specific antigens of
Pseudomonas pseudomallei and evaluation of their efficacies for diagnosis of
melioidosis . -
pubmed
All antigens were used for detecting antibody in sera from
patients with
septicemic melioidosis by indirect enzyme - linked immunosorbent assay . -
pubmed
Eight
patients suffering from unilobar
Caroli ' s disease underwent liver resection during a period of six years . -
pubmed
Despite the availability of free or low - cost public sector
human immunodeficiency virus (
HIV ) health - care services , important inequities in utilization exist . -
pubmed
Eye movement dysfunction vs.
language delays in migrant
children . -
pubmed
The case histories are reported of two
patients with
systemic lupus erythematosus (
SLE ) who developed fatal neurological involvement , each presenting with cerebellar and brainstem signs . -
pubmed
Two
women ( 4.8 % ) had thyroid function test abnormalities observed at screening , three ( 7.3 % ) had a spontaneous
miscarriage , and eight ( 19.5 % ) women were noncompliant with follow - up . -
pubmed
A permanent
ischemia leading to
cerebral infarction was induced after microsurgical exposure and occlusion of the internal carotid , anterior , and middle cerebral arteries in the
rabbit . -
pubmed
Abnormalities of chromosome 22 in
human brain tumors determined by combined cytogenetic and molecular genetic approaches . -
pubmed
Nevertheless , discrepancies between the cytogenetic and molecular findings were observed in several cases , suggesting that the use of both methodologies in combination might provide key information on the incidence and extent of the abnormalities involving chromosome 22 in
human brain tumors . -
pubmed
Therefore a study in 8
patients suffering from
allergic rhinitis was conducted . -
pubmed
SUBJECTS AND DESIGN :
Patients with uncomplicated
essential hypertension ( n = 36 ) with a
diastolic blood pressure of 95 - 115 mmHg were studied . -
pubmed
METHODS : In a retrospective study , we looked at the records of 76 consecutive
patients ( 86 eyes ) presenting with
epiphora over a period of 2 years ( January 1993 to December 1994 ) . -
pubmed
CASE REPORT : An
HIV - infected man developed
cutaneous leishmaniasis and disseminated
histoplasmosis with
buccal lesions concomitantly . -
pubmed
The spheroid model of culture is a good opportunity to study a resistance type which looks close to the
tumour resistance found in vivo in
mice and in
patients . -
pubmed
UNLABELLED : To establish the influence of nonsteroidal anti - inflammatory drugs ( NSAIDs ) on the clinical course of
upper gastrointestinal bleeding (
UGIB ) , we designed a longitudinal cohort study to assess the effect of prior use of these drugs on several outcome variables in
patients with
UGIB . -
pubmed
RESULTS : 164 ( 46.6 % ) of 352
patients with
UGIB consumed NSAIDs in the week previous to the onset of
bleeding . -
pubmed
On endoscopic examination ,
gastric ulcer was the most frequent lesion in
patients with NSAIDs as compared to
duodenal ulcer in patients without NSAID use ( p & lt ; 0.0001 ) . -
pubmed
We have studied the methylation patterns in two 650 kb double minute chromosomes present in two
mouse tumor cell lines , resistant to
methotrexate . -
pubmed
We measured the whole blood chemiluminescence in 59
patients before and after open surgery ( surgery by a laparotomy ) for
gastrointestinal disease . -
pubmed
Early postoperative
infection was detected in 12 ( 20.3 % ) of the 59
patients . -
pubmed
In
L3.6pl tumors established in the pancreas of
nude mice , systemic therapy with C225 alone and C225 in combination with
gemcitabine resulted in growth inhibition ,
tumor regression , and abrogation of metastasis ; median
tumor volume was reduced from 538 to 0.3 and to 0 mm3 , respectively . -
pubmed
Effect of
polaprezinc on healing of
acetic acid - induced
stomatitis in
hamsters . -
pubmed
METHOD :
Stomatitis was induced in
hamsters by local injection of 30 microL of 10 %
acetic acid solution into both cheek pouches . -
pubmed
CONCLUSION :
Polaprezinc is an effective treatment in this
animal model of
acetic acid - induced
stomatitis . -
pubmed
Extrapolating these to
humans suggests that the drug has healing effect to severe
stomatitis induced by anticancer drug therapy . -
pubmed
Moreover , they suggest a novel molecular mechanism for a subset of
human malformative syndromes of the CNS . -
pubmed
We have used the
Friend virus model to determine the basic mechanisms by which the immune system can control persistent
retroviral infections . -
pubmed
[ Familial complicated
optic disc drusen in a
child ] . -
pubmed
We report a case of a 15 - year - old
child with
optic disc drusen with known familial inheritance and
disc swelling . -
pubmed
Glibenclamide effects on reperfusion - induced
malignant arrhythmias and left ventricular mechanical recovery from stunning in conscious
sheep . -
pubmed
INTRODUCTION :
Sulfonylureas have been associated with a high incidence of
cardiovascular death in
diabetic patients treated with these drugs . -
pubmed
OBJECTIVE : The purpose of this study was to assess whether
glibenclamide elicits protection on postischemic myocardial functional recovery ( stunning ) and against reperfusion - induced
arrhythmias in a conscious
sheep model . -
pubmed
Cervical phrenic nerve block for intractable
hiccups in
cancer patients . -
pubmed
RESULTS : By 8 weeks of age , control db / db
mice developed
hyperglycaemia ( fasting : 10.4+/-0.5 mmol / l ) ,
hyperinsulinaemia and
impaired glucose tolerance . -
pubmed
METHODS : 34
patients , who after isolated coronary bypass procedure developed non - Q or Q wave
infarction were selected for the study . -
pubmed
The study was conducted retrospectively and included
patients with stable , unstable , and
postinfarction angina without preoperative enzymatic evidence of
ischemic injury and with technically noncomplicated coronary bypass grafting . -
pubmed
RESULTS : Most
patients in both groups had triple - vessel disease ( 10 of 12
patients group A ; 17 of 22
patients group B ) , all
patients received complete revascularization ; 7 of 12
patients in group A and 5 of 22
patients in group B had significant or critical
left main stem stenosis . -
pubmed
The aim of the present study was to identify treatment - related factors that might be associated with the transition of
secondary hyperparathyroidism to
tertiary hyperparathyroidism in
patients with
X - linked hypophosphatemic rickets . -
pubmed
DESIGN : Thirteen
patients with
X - linked hypophosphatemic rickets and secondary or tertiary
hyperparathyroidism were included in the study . -
pubmed
RESULTS : Two
patients developed tertiary
hyperparathyroidism and 11
patients secondary
hyperparathyroidism during the treatment . -
pubmed
Patients with
tertiary hyperparathyroidism had , on average , earlier onset and longer duration of treatment , higher dose of Pi and longer duration of treatment with very high Pi doses ( & gt ; 100 mg / kg / day ) compared to the 11
patients with
secondary hyperparathyroidism . -
pubmed
Cephalometric assessment of the posterior airway space in
patients with
cleft palate after palatoplasty . -
pubmed
The purpose of the present investigation was to analyze cephalometric alterations between
patients with
cleft palate and a noncleft control group in an obstructive
sleep disordered breathing - specific tracing . -
pubmed
The cohort included 33
subjects ( 13
females , 20
males ; mean age 12.1 + /- 3.8 years , mean
body mass index 17.5 + /- 2.9 kg / m(2 ) ) with surgical closure of a
unilateral or bilateral cleft palate and a matched control of noncleft participants . -
pubmed
RESULTS : Compared with the controls ,
patients with
cleft palate had a significant narrow anterior - posterior dimension of the pharynx at the level of the maxillary plane and the narrowest width , a more downward hyoid position , and a longer uvula . -
pubmed
CONCLUSIONS :
Patients with
cleft palate appear to present pharyngeal and craniofacial distinctive features that characterize patients with obstructive
sleep disordered breathing and differ from those of a noncleft control . -
pubmed
Results of valvulotomy for
valvular pulmonary stenosis with intact ventricular septum ; analysis of sixty - nine
patients . -
pubmed
ELECTRON MICROSCOPIC EXAMINATION OF
YOSHIDA ASCITES HEPATOMAS . -
pubmed
[ Therapeutic action of
sterosan - hydrocortisone in various
superficial dermatoses , with special reference to the
dermatoses caused by
Candida ] . -
pubmed
The effect of
PAP 9704 , a traditional prescription in Korea consisting of
Polygala tenuifolia ,
Acorus gramineus , and
Poria cocos at a ratio of 1:1:1 ( dry weight ) , on
methamphetamine (
MA)-induced
hyperlocomotion was examined in
mice . -
pubmed
Two
patients died without preceding signs of
progressive external ophthalmoplegia . -
pubmed
Characteristic shear rates preventing adhesion to the bottom plate were around 10 and 1.0 s(-1 ) for the bacteria on glass and the
PEO - brush and 36 and 3.4s(-1 ) for the
yeast strain on glass and the
PEO - brush , respectively . -
pubmed
The factors associated with increased mortality during ICU stay included increased
patient age , allogeneic transplant , intubation / mechanical ventilation ,
multiorgan system failure (
MOSF ) , presumed / documented
infection ,
graft - versus - host disease , and higher APACHE and O - PRISM score at ICU transfer . -
pubmed
Technical considerations are discussed as well as possible advantages of this approach including decreased
blood loss , faster
patient recovery and improved visualization . -
pubmed
The sequence of the 16S ribosomal RNA gene of the bacterium indicated a phylogenetic position of the
strain within the genus Sphingopyxis , and the
strain was therefore designated
Sphingopyxis sp . - pubmed
Thus , we compared outcomes from the Do
Tirofiban and ReoPro Give Similar Efficacy Outcome Trial ( TARGET ) for
patients who underwent multivessel versus single - vessel PCI and separately considered the effect of
acute coronary syndromes on the results . -
pubmed
Safety analysis included in -
patient major and minor
bleeding . -
pubmed
In addition , in a propensity - matched analysis that included 810
patients with
acute coronary syndrome , multivessel stenting resulted in numerically more
ischemic events than did single - vessel stenting , although this did not reach statistical significance ( hazard ratio 1.32 , 95 % confidence interval 0.85 to 2.05 , p = 0.221 ) . -
pubmed
Street
heroin induces
mitochondrial dysfunction and apoptosis in
rat cortical neurons . -
pubmed
Thus , we analysed the apoptotic pathways involved in street
heroin neurotoxicity using primary cultures of
rat cortical neurons . -
pubmed
DESIGN : A hospital - based association study on
degenerative and vascular dementia patients proven on the basis of clinical profile and MRI . -
pubmed
PARTICIPANTS : A group of 107
dementia patients and 162 age- and sex - matched controls from a North Indian cohort participated in the study . -
pubmed
Increased NoGo - anteriorisation in first - episode
schizophrenia patients during Continuous Performance Test . -
pubmed
While it is known that
patients with
chronic schizophrenia exhibit a significant reduction in NGA , it is unclear whether this also occurs in
patients undergoing their first - episode . -
pubmed
CONCLUSIONS : Attention was reduced in
patients with first - episode
schizophrenia , as indicated by more false reactions , prolongation of reaction time , P300 - latencies and by a decrease in P300 - amplitude . -
pubmed
Significantly however , the NGA and prefrontal LORETA - sources indicate intact prefrontal brain structures in first - episode
schizophrenia patients . -
pubmed
SIGNIFICANCE : The results support the idea of a possible new biological marker of first episode
psychosis , which may be a useful parameter for the longitudinal measurement of changing prefrontal brain function in a single
schizophrenia patient . -
pubmed
Brain abscess caused by
Nocardia nova . -
pubmed
We describe a patient with a
brain abscess caused by
N. - pubmed
This is the first detailed report of
central nervous system infection due to
N. - pubmed
Inoculation with the neurotropic JHM
strain of
mouse hepatitis virus (
JHMV ) into the central nervous system ( CNS ) of
mice results in an acute
encephalitis associated with an immune - mediated
demyelinating disease . -
pubmed
Of 20
patients followed - up , nine were alive in remission , two alive in disease , one died of treatment related complication , four died of progressive
lymphoma , four died of
AIDS related causes . -
pubmed
As a substantial portion of the
patients remains alive disease free , the impact of HAART on the clinical course of
ARL needs further follow - up and evaluation . -
pubmed
Some of such proteins could be autoantigens that extend the
ocular inflammation in
human endogenous uveitis . -
pubmed
Six weeks after immunization , the presence of autoantibodies against the retinal proteins in
mice with
EAU were examined by two - dimensional electrophoresis followed by western blotting ( 2D - WB ) . -
pubmed
METHODS : Thirty - one
patients with CS
DAVFs ( 33 lesions ) underwent TVE . -
pubmed
Although
patients harboring lesions with a greater coil volume required a longer recovery time , newly developed or aggravated
CNP , related to 84.6 % of the lesions , resolved completely . -
pubmed
This study examined the efficacy and tolerability of the opioid antagonist
naltrexone in
adults with
kleptomania who have urges to steal . -
pubmed
Twenty - five
individuals with
DSM - IV kleptomania were randomized to
naltrexone ( dosing ranging from 50 mg / day to 150 mg / day ) or placebo . -
pubmed
Subjects assigned to
naltrexone also had greater improvement in overall
kleptomania severity ( reflected in the CGI scores ) ( p & lt ; .001 ) . -
pubmed
PATIENTS : Patients included 172 consenting
HD patients who had been on
HD for at least 3 months and were mentally stable . -
pubmed
Living donor kidney transplantation ( KT ) is the treatment of choice for
end - stage renal disease patients and exhaustive assessment of the potential live kidney donor leads to successful KT in most occasions . -
pubmed
OBJECTIVE : We evaluated
asthma patients who underwent long - term treatment with a new ICS to determine if they had tooth problems that were related to
osteoporosis of the mandible . -
pubmed
RESULT :
Asthma patients with
tooth loss ( n = 36 ) and with
caries or other
tooth problems ( n = 28 ) were found to have a significantly higher prevalence of
osteoporosis in the mandible than those without
tooth problems ( n = 17 ; 22.2 % , 7.1 % , 0 % , respectively ; chi(2 ) = 6.34 , p & lt ; 0.05 ) . -
pubmed
Hyperhomocysteinemia in
levodopa - treated
patients with
Parkinson ' s disease dementia . -
pubmed
Increased
Hcy levels have been observed in
levodopa - treated
patients with
PD . -
pubmed
We performed a multicenter cross - sectional study on
patients with
PD with (
PDD ) and without (
PDnD )
dementia and age- and sex - matched healthy controls . -
pubmed
We compared
Hcy levels in
patients with
PDD and
PDnD and healthy controls , and we performed logistic regression analysis to search for an association between the presence of
dementia and increased
Hcy levels in
PD . -
pubmed
Patients with
PD ( 121 ) ,
PDD ( 42 ) , and
PDnD ( 79 ) , and age- and sex - matched controls ( 154 ) were enrolled . -
pubmed
Hcy levels were higher in
patients with
PD compared to controls ( 17.5 micromol / L + /- 10.2 vs. 11 + /- 4.1 ; P < 0.00001 ) . -
pubmed
Among
patients with
PD ,
Hcy levels were higher in the
PDD group compared to the PDnD group ( 20.7 micromol / L + /- 12.1 vs. 15.8 + /- 8.5 ; P = 0.002 ) . -
pubmed
A 14 - year - old adolescent
girl with a diagnosis of recurrent
embryonal - botryoidal rhabdomyosarcoma was referred to us . -
pubmed
Based on its pathogenesis , in addition to a number of correlative studies , immunotherapy represents a potential therapeutic option for
patients with
HCC . -
pubmed
It has been shown that these suppressor cells mask
tumor - specific immune responses in
patients with
HCC . -
pubmed
Different immunotherapeutic approaches including peptide- and dendritic cell - based therapies have demonstrated promising results in
patients with
HCC . -
pubmed
METHODS : Male C57BL/6
mice were subjected to a major
burn ( 3rd degree , 25 % TBSA ) or sham treatment . -
pubmed
It is a main theme of ophthalmologic research , because
retinopathies are common causes of
blindness in all age groups : age - related
macular degeneration in the elderly ,
diabetic retinopathy in the middle aged , and
retinopathy of prematurity and
retinoblastoma in
children . -
pubmed
OBJECTIVE : To identify functional outcomes that could justify the need for a rehabilitation care program for
patients with
metastatic epidural spinal cord compression (
MESCC ) and
paraplegia . -
pubmed
Quantitative trait loci for resistance to
fusarium head blight in a
Chinese wheat landrace Haiyanzhong . -
pubmed
The major QTL on 7D can be used to improve the FHB resistance in
wheat breeding programs and add diversity to the
FHB resistance gene pool . -
pubmed
Amerithrax , the investigation into the
anthrax letter attacks , applied high - resolution whole - genome sequencing and comparative genomics to identify key genetic features of the letters '
Bacillus anthracis Ames strain . -
pubmed
Patients were evaluated using the
anterior knee pain score of Kujala et al . -
pubmed
Lipogenic gene expression in abdominal adipose and liver tissues of diet - induced
overweight cats . -
pubmed
Spinal cord injury with persistent
paraplegia occurred in 1/19 ( 5.2 % )
patients . -
pubmed
Determinants of
warfarin use and international normalized ratio levels in
atrial fibrillation patients in Japan . -
pubmed
BACKGROUND : Determinants of
warfarin use and anticoagulation levels in
atrial fibrillation (
AF )
patients have not been clarified thoroughly . -
pubmed
Target INR levels for non - valvular
AF patients were 1.6 - 2.6 for
patients aged & gt;= 70 years and 2 - 3 for
patients aged & lt ; 70 years . -
pubmed
Those for
patients with
valvular AF were 2 - 3 . -
pubmed
Patients with non - valvular
AF and CHADS2 score & gt;= 1 receiving
warfarin ( n = 5,614 ) more frequently had permanent
AF ,
congestive heart failure , and
stroke or
transient ischemic attack (
TIA ) , and had higher CHADS2 scores than those not receiving
warfarin . -
pubmed
Example plans were generated for 10 of the
patients in the study who exhibited significant
hypoxia . -
pubmed
We created an IMRT plan for each
patient with a simultaneous integrated boost ( SIB ) to the
hypoxic sub - volumes . -
pubmed
Letter :
diabetic polyneuropathy and
cardiovascular complications in
type 2 diabetic patients (
diabetes metab j 2011;35:390 - 6 ) . -
pubmed
The aim of this study was to compare the in vitro activity of
ethanol ,
EDTA and
levofloxacin (
Levo ) , alone or in combination , on biofilms of
Stenotrophomonas maltophilia recovered from patients with catheter - related
bloodstream infections (
CRBSIs ) at a university hospital in Argentina . -
pubmed
First , 24 and 48 h biofilms were formed in microtitre plates and challenged with 25 or 40 %
ethanol for 1 h. Biofilms , of the 14 local isolates and from the reference
strain K279a , were eradicated after both treatments as shown by plate counts and the regrowth technique . -
pubmed
Leishmania major infection in humanized
mice induces
systemic infection and provokes a nonprotective
human immune response . -
pubmed
We show that inflammatory
human macrophages get infected with Leishmania parasites at the site of
infection . -
pubmed
However , the
human immune system is not able to prevent
systemic infection . -
pubmed
Comparable to some
Miltefosine treated
patients , humanized
mice developed severe side effects , which are not detectable in the classical
murine model of experimental
leishmaniasis . -
pubmed
[
Streptococcus suis meningitis in a meat factory employee ] . -
pubmed
BACKGROUND : In the Netherlands ,
Streptococcus suis is a rare cause of
meningitis . -
pubmed
CASE DESCRIPTION : At the Emergency Department , a 60 - year - old
man presented with
headache ,
confusion ,
fever and
nuchal rigidity . -
pubmed
CONCLUSION : Particularly people who are in close contact with
pigs have an increased risk of
S. - pubmed
Rodent model in
caries research . -
pubmed
The
rodent model of dental
caries has made fundamental contributions to the understanding of the etiology , pathogenesis , and prevention of this disease . -
pubmed
A psychometric validation of two brief measures to assess palliative need in
patients severely affected by
multiple sclerosis . -
pubmed
CONTEXT : Most patient - reported outcome measurement tools in
multiple sclerosis (
MS ) are geared toward less severely affected
patients . -
pubmed
Palliative care outcome measures have not been validated in
patients with
MS . -
pubmed
Twenty - seven
patients with
diabetic foot ulcers (
foot ulcer group ) , 27
patients without
diabetic foot ulcers (
diabetic control group ) and 27 healthy controls were enrolled . -
pubmed
SPA appears to be higher in
patients with
diabetic foot ulcers when compared with
patients without
diabetic foot ulcers and healthy controls . -
pubmed
Clinical factors associated with left ventricular ejection fraction disparity in
patients with
left ventricular dysfunction undergoing multimodality imaging . -
pubmed
In 119
patients with
left ventricular dysfunction who underwent both echocardiography and stress testing with nuclear imaging within seven days ( but with significant disparity in reported left ventricular ejection fraction ) , we identified four clinical variables which were associated with left ventricular ejection fraction difference . -
pubmed
BACKGROUND : Serum
phosphorus control is critical for
chronic kidney disease (
CKD ) 5D
patients . -
pubmed
OBJECTIVE : To establish the efficacy , safety , and tolerability of
lanthanum carbonate in
CKD 5D patients . -
pubmed
CONCLUSION :
Lanthanum carbonate is an efficacious and well - tolerated oral
phosphate binder with a mild AE profile in hemodialysis and
CAPD patients . -
pubmed
This agent may provide an alternative for the treatment of
hyperphosphatemia in
CKD 5D
patients in mainland China . -
pubmed
Though approximately half of the
patients recover , the clinical course is highly variable and some patients develop refractory
heart failure and persistent
left ventricular systolic dysfunction . -
pubmed
Adenovirus (
ADV ) types 4 (
ADV-4 ) and 7 (
ADV-7 ) are presently the major cause of
febrile acute respiratory disease (
ARD ) in U.S. military recruits . -
pubmed
The primary endpoints were prevention of
febrile ARD due to
ADV-4 and seroconversion of neutralizing serum antibodies to
ADV-7 , which was not expected to circulate in the study population during the course of the trial . -
pubmed
It is important to differentiate progressive from nonprogressive
precocious puberty to avoid unnecessary treatment for the latter ; if diagnosis is uncertain , the
child should be reassessed within several months . -
pubmed
Gonadotropin - releasing hormone agonists should be considered only for
children with progressive
central precocious puberty to prevent
short stature . -
pubmed
For
children with apparent nonprogressive
precocious puberty , follow - up every 3 to 6 months between ages 6 and 7 years is recommended to assess for progression . -
pubmed
Epidemiology of
human leishmaniasis in Greece , 1981 - 2011 . -
pubmed
Transcatheter aortic valve replacement ( TAVR ) in
patients with systemic
autoimmune diseases . -
pubmed
[ Fate of the pancreas in the
guinea pig after
death of the
animal ] . -
pubmed
Endoscopic finding of
RAC ( regular arrangement of collecting venules ) in the angle of stomach suggests lack of
infection with
H. - pubmed
RESULTS : The percentage of healthy
children aged 6 years , who did not have any signs of
dental caries manifested with cavity ,
tooth filling or
tooth loss was only 14.4 % . -
pubmed
We performed a retrospective analysis on 535 consecutive
laryngeal cancer patients submitted to open partial laryngectomy at the Otolaryngology - Head and Neck Surgery Department of Florence University to evaluate a possible correlation between smoking and surgical complications . -
pubmed
Patients were grouped in non smokers and smokers and evaluated for airway , swallowing , local and
fistula complications by multivariate analysis : 507 ( 95 % )
patients were smokers , 69 % presented supraglottic , 30 % glottic and 1 %
transglottic cancer . -
pubmed
Mouse models of
primary central nervous system lymphomas : tools for basing funding and therapeutic strategies . -
pubmed
Indeed , several limitations of
human sample present a major obstacle to the identification of the particular microenvironment of the sanctuary sites where these
tumor cells grow . -
pubmed
In addition , the generally poor overall condition and performance status of
patients with
PCNSL limit their participation in prospective trials . -
pubmed
Therefore ,
animal models of
PCNSL are essential for
tumor microenvironment characterization and for antitumor response studying . -
pubmed
In this review , we have compiled the B - and T - cell PCNSL
mouse models that are used to improve our understanding of the
lymphoma microenvironment , tropism and migration and to investigate novel therapeutic strategies . -
pubmed
While this will not obviate the use of free tissue transfer , it may add to the surgical armamentarium for aesthetic restoration in the
breast cancer patient . -
pubmed
RESULTS : Seventeen
patients ( mean age 83.95 + -5.84 ) developed
retinal pigment epithelium tears . -
pubmed
Getting to the heart of the matter :
cardiovascular disease in patients with
HIV . -
pubmed
METHODS : Thirty - six
patients , treated with
TPA followed up by full fixed appliances , were divided into stable and
relapse groups based on the long - term presence or not of
relapse . -
pubmed
Based on the results obtained with the acaricide - sensitive laboratory
strain , acaricides were selected to test against eggs , larvae , and adults of four field populations of
T. - pubmed
The chronic
toxicity of inorganic
Hg -
Hg ( II )--through food or soil contaminations was therefore assessed for the snail
Cantareus aspersus , a well - recognized soil quality bioindicator . -
pubmed
We investigated whether phagocytosis participates in the protection of insects from
viral infection using the natural host - virus interaction between
Drosophila melanogaster and
Drosophila C virus (
DCV ) . -
pubmed
Drosophila S2 cells were induced to undergo apoptotic cell
death upon
DCV infection . -
pubmed
To validate the in vivo situation , adult flies were abdominally infected with
DCV , followed by the analysis of fly
death and viral growth . -
pubmed
Furthermore , hemocytes isolated from infected flies contained
DCV - infected cells , and preinjection of latex beads to inhibit the phagocytic activity of hemocytes accelerated fly
death after
viral infection . -
pubmed
RESULTS :
FTLD patients carrying the D * genotype ( H / D or D / D ) showed greater
atrophy in the basal ganglia , bilaterally , compared to H / H carriers ( x , y , z : -22 , -4 , 0 ; T = 3.45 ; cluster size : 33 voxels , x , y , z : 24 , 4 , -2 ; T = 3.38 ; cluster size : 36 voxels ) . -
pubmed
Analysis of Local Recurrence Following Proximal Gastrectomy in
Patients with Upper Third
Gastric Cancer . -
pubmed
PURPOSE : Little is known about local
recurrence following proximal gastrectomy in
patients with upper third
gastric cancer . -
pubmed
We performed this study to evaluate the long - term results of a proximal gastrectomy , and to analyze the risk factors of local
recurrence affecting survival in these
patients . -
pubmed
MATERIALS AND METHODS : We undertook a retrospective study of 63
patients who underwent potentially curative proximal gastrectomy between 1990 and 1999 , with special reference to local
recurrence . -
pubmed
RESULTS : During a median follow - up period of 37 months , 25 of the 63
patients ( 39.7 % ) developed a
recurrence of
cancer , with local
recurrence in 15
patients ( 23.8 % ) , the majority of these occurring at the remnant stomach or anastomosis . -
pubmed
Reoperation for cure was possible in only 4
patients and most died within the first year following diagnosis of
recurrence . -
pubmed
We investigated the relationship between RI and cardiac function , and evaluated the utility of RI for predicting cardiac events in
patients with
CVD . -
pubmed
METHODS AND RESULTS : Renal Doppler ultrasonography and echocardiography were performed in a total of 452
patients with
CVD . -
pubmed
OBJECTIVE : To understand phenotypic and molecular characteristics of
patients with clinically " definite "
primary lateral sclerosis (
PLS ) in a prospective study . -
pubmed
METHODS : Six sites enrolled 41
patients who had pure
upper motor neuron dysfunction ,
bulbar symptoms , a normal EMG done within 12 months of enrollment , and onset of symptoms & gt;=5 years before enrollment . -
pubmed
Patients with locally advanced
oropharyngeal cancer are at risk for poor outcomes due to the multi - modal nature of treatment and the potential for treatment - related
toxicity . -
pubmed
AA preferentially affects
pigmented hairs , and the hair of
patients with
AA frequently shows a change in colour when it regrows following an acute episode of
AA . -
pubmed
BACKGROUND :
Metastases are the most common reason of
cancer death in
patients with
solid tumors . -
pubmed
Echinococcus granulosus infection in
dogs in Sidi Kacem Province ( North - West Morocco ) . -
pubmed
Herein we report two
patient cases with
mesothelioma who received second - line chemotherapy with the combination of
cisplatin and the novel compound
lurbinectedin . -
pubmed
CONCLUSIONS : The mortality rate of
nontuberculous mycobacterial disease among
HIV - uninfected individuals has increased in the United States between 1999 and 2014 . -
pubmed
BACKGROUND : There are a range of opinions on the benefits and thresholds for the transfusion of red blood cells in
critically ill patients with
traumatic brain injury (
TBI ) and an urgent need to understand the neurophysiologic effects . -
pubmed
The aim of this study was to examine the influence of red blood cell transfusions on cerebral tissue oxygenation ( SctO2 ) in
critically ill TBI patients . -
pubmed
METHODS : This prospective observational study enrolled consecutive
TBI patients with
anemia requiring transfusion . -
pubmed
RESULTS : We enrolled 24
patients with severe
TBI , of which five
patients ( 21 % ) were excluded due to poor SctO2 signal quality from large subdural
hematomas and bifrontal decompressive craniectomies . -
pubmed
CONCLUSIONS : The bifrontal method of recording changes in NIRS signal was not able to detect a measurable impact on SctO2 in this sample of
patients receiving red blood cell transfusion therapy in a narrow but conventionally relevant , range of
anemia . -
pubmed
Human respiratory syncytial virus (
RSV ) is an enveloped RNA virus that is the most important viral cause of acute pediatric
lower respiratory tract illness worldwide , and lacks a vaccine or effective antiviral drug . -
pubmed
A 37 - year - old male
patient presented with
fever , incomplete
paralysis of
bilateral legs , and
bullous eruptions 8 months after allogeneic transplant . -
pubmed
While there is a wide range of neoplastic and
non - neoplastic skin diseases for which
ALA - PDT is used in adults , there is a knowledge gap when it comes to its use in
children . -
pubmed
ALA - PDT has been used successfully in
children to reduce the number and size of
basal cell tumors , inflammatory
acne lesions ,
plantar warts , and linear
porokeratoses . -
pubmed
ALA - PDT may be an attractive alternative to surgery for
children with
basal cell nevus syndrome , or to conventional destructive and/or topical methods used for
plantar warts or linear
porokeratoses . -
pubmed
METHODS : Sixty - nine
patients with a mean age of 15.3 + - 1.9 years completed a neurocognitive , vestibular / ocular motor , and symptom assessment within 7 days of a diagnosed
concussion . -
pubmed
Age , pre - treatment sputum smear grading ,
HIV status and
TB disease classification influenced two - month sputum smear non - conversion . -
pubmed
Integrated treatment models are effective for early
psychosis ( SMD -0.38 , 95 % CI -0.53 to -0.22 ) as long as the
patients remain in treatment . -
pubmed
In liver transplantation
patients ,
CMV infection and BPAR were closely associated with T cell population changes . -
pubmed
The increasing awareness of population , the burden of new types of disease , as well as the
recurrence of food scandals have recently launched a scientific and population debate on the contribution of foods items , especially those of animal origin , to the toxic exposure of food producing animals and
humans . -
pubmed
The rate of acute adverse reactions and contrast - induced
nephropathy is lower than in
adults . -
pubmed
The relationship between
nephrogenic systemic fibrosis and
gadolinium administration is well established and only a small number of
children suffer from this debilitating disorder . -
pubmed
The recent finding of
gadolinium deposition in the brain of
patients with normal renal function has renewed concerns regarding its long - term
toxicity . -
pubmed
The anti -
hyperuricemic effect of
epigallocatechin-3 - gallate (
EGCG ) on
hyperuricemic mice . -
pubmed
This study aimed to evaluate the antihyperuricemic activity of
EGCG on
hyperuricemic mice . -
pubmed
These results presented that
EGCG had obvious
hypouricemic and renal protective effects on
hyperuricemic mice . -
pubmed
Pattern onset / offset ERGs to pedestal stimulation may be used to probe simultaneous recording of ERGs with VEPs in order to obtain an assessment of retinal
ganglion cell and optic pathway function in
patients with less stable fixation . -
pubmed
[ Radiofrequency catheter ablation of
premature ventricular contractions in
children under CARTO3 system : a retrospective study from one single center ] . -
pubmed
Objective : To evaluate the clinical effect and summarize the experience of radiofrequency catheter ablation ( RFCA ) for
children suffered from
premature ventricular contractions (
PVCs ) . -
pubmed
Conclusion : RFCA is safe and effective for
PVCs in
children with high success rate and low
recurrence and complication rates . -
pubmed
Delayed diagnosis of primary
vesicoureteral reflux in
children with recurrent
urinary tract infections : Diagnostic approach and renal outcomes . -
pubmed
RESULTS : A total of 32
children ( female , n=27 : 84.4 % ) with a mean age of 7.67 + -3.34 years at the time of diagnosis of
VUR were included in the study . -
pubmed
Tc-99mDMSA detected abnormalities in 83.9 % ( 7 with a single
scar , 7 with multiple lesions , 12 with
reduced kidney function ) of the
patients . -
pubmed
In 5
patients ( 16 % ) ,
VUR could not be predicted by US+
DMSA scintigraphy ( Grade IV VUR in 3 and Grade III in 2 cases ) . -
pubmed
Moreover , our findings can be useful in the identification of genotype to phenotype relationship in patients , and provide future abilities for confirmatory diagnostic testing , prognosis , and predict the severity of
PKU patients . -
pubmed
These results indicate that repeated exposures to the nerve agent ,
DFP at doses that are below the threshold for
acute toxicity , can result in alterations in myelin structure and persistent decreases in axonal transport in the
rodent brain . -
pubmed
These observations could explain some of the long - term
neurological deficits that have been observed in
humans who have been repeatedly exposed to OPs . -
pubmed
The control group consisted of 129
patients who underwent open suturing of perforated
ulcer followed by conventional treatment in postoperative period . -
pubmed
In 129
patients of the control group open suturing of the perforated
ulcer and conventional postoperative therapy were applied . -
pubmed
CONCLUSION : Laparoscopic treatment of perforated
ulcers facilitates application of fast track rehabilitation program in emergency
patients . -
pubmed
Young
Man With
Unilateral Neck Swelling . -
pubmed
Anti - proliferative activity of these structures was tested in vitro against a panel of five
human cancer cell lines , including prostate (
PC-3 ) , colon (
HT-29 ) ,
leukemia (
CCRF - CEM ) , lung (
HTB-54 ) and breast (
MCF-7 ) . -
pubmed
Materials and Methods : In this cross - sectional retrospective study , we analyzed 39
patients who underwent radical orchiectomy due to a
testicular cancer ( Group 1 ) and 82
patients on whom varicocelectomy procedure was performed as control group ( Group 2 ) between January 2006 and January 2016 in our clinic . -
pubmed
METHODS : Keratinocytes isolated from the skin of healthy
subjects ( n = 20 ) and
patients with
atopic dermatitis ( n = 20 ) as well as
HaCaT and
PCS-200 - 010 cell were exposed to the 900 MHz electromagnetic field for 60 minutes . -
pubmed
Of the 14
patients who had undergone embolization as initial treatment , 5 ( 36 % ) had developed a
recurrence within an average of 29.6 months ( range , 2 - 87 ) . -
pubmed
None of
patients in the surgical group developed
recurrence . -
pubmed
A multidisciplinary and ordered decision is crucial for the treatment choice to ensure better outcomes , especially for
patients with a definite
neurologic deficit at diagnosis . -
pubmed
CASE PRESENTATION :
Patient 1 was a 16 - year - old
boy diagnosed with bilateral
JOAG and
high myopia . -
pubmed
Patient 3 was a 35 - year - old
man with bilateral
JOAG . -
pubmed
CONCLUSIONS : This case series describes three
patients with concomitant occurrence of
JOAG and
LHON . -
pubmed
Primary outcome variables included comparisons of incidence and 5 - year overall survival in kidney transplant
recipients versus nonrecipients after treatment of
prostate cancer . -
pubmed
Methods : A retrospective analysis was performed on the screening data of elderly women ( & gt;=50 years ) who had examination at
cervical lesion clinic in Peking University People 's Hospital and Affiliated Hospital of Guizhou Medical University from January 2013 to January 2014 , with histopathology as the gold standard , to compare screening effectiveness of cervical cytology or
HPV detection for elderly women in
cervical cancer screening in the two regions . -
pubmed
Vitamin D and probiotic co - supplementation affects mental health , hormonal , inflammatory and oxidative stress parameters in
women with
polycystic ovary syndrome . -
pubmed
OBJECTIVE : The aim of this study was to determine the effect of
vitamin D and probiotic co - administration on mental health , hormonal , inflammatory and oxidative stress parameters in
women with
polycystic ovary syndrome (
PCOS ) . -
pubmed
Candida albicans and
Actinomyces viscosus are prominent microbes associated with dental root
caries . -
pubmed
We hypothesized that the use of local dental anesthesia with
lidocaine with and without
epinephrine is safe and does not result in life - threatening
arrhythmias in
patients with
channelopathies . -
pubmed
Fifty - six dental procedures were performed in 28
patients ( 18
women , 10
men ) with
cardiac channelopathies : 16 ( 57.1 % ) had
long - QT syndrome , and 12 ( 42.9 % ) had
Brugada syndrome ; 11 ( 39.3 % ) of patients had an implantable defibrillator . -
pubmed
In
patients with
long - QT syndrome , the median corrected QT was higher , from 450.1 to 465.4 ms ( P=0.009 ) at the end of anesthesia in
patients in whom
epinephrine was used . -
pubmed
Conclusions The use of local dental anesthesia with
lidocaine , regardless of the use of a vasoconstrictor , did not result in life - threatening
arrhythmias and appears to be safe in stable
patients with
cardiac channelopathies . -
pubmed
CONCLUSIONS : Despite the relative economic homogeneity of the cohort , lower education level is associated with increased subclinical
atherosclerosis , mainly mediated by the higher and more frequent
tobacco consumption . -
pubmed
PURPOSE OF REVIEW : This review highlights recent advances in the diagnosis and management of
children with
heart failure . -
pubmed
We emphasize the clinical approach to
patient care in the areas of acute decompensated
heart failure , chronic
heart failure , and failure of the
patient with single ventricle physiology . -
pubmed
RECENT FINDINGS : Important guidelines regarding the recognition and management of
heart failure in
children have been proposed and adopted , providing guidance for early recognition and ongoing management . -
pubmed
SUMMARY : Improved outcomes in
children with
heart failure are possible . -
pubmed
Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support in a
Patient with
Panhypopituitarism : A Case Report . -
pubmed
METHODS : All consecutive , technical inoperable or residual
CTEPH patients receiving
bosentan or
macitentan , diagnosed in our multidisciplinary team between January 2003 and January 2019 , were included . -
pubmed
CONCLUSION :
CTEPH patients receiving
bosentan or
macitentan have improved clinical outcomes till 2 - year follow - up , without significant differences in outcomes between both therapies . -
pubmed
Post - Traumatic Endophthalmitis Caused by
Oerskovia turbata . -
pubmed
Case Report : A patient presented with chronic
endophthalmitis that occurred after
ocular trauma with organic material and
Oerskovia turbata was eventually isolated . -
pubmed
Conclusion : This is the first reported
patient with
endophthalmitis due to
O. - pubmed
turbata , a Gram - positive bacillus found in soil that rarely causes
human infection . -
pubmed
DESIGN : Four stimulation protocols combining 20 and 40 Hz average frequency with either constant frequency trains or with doublet frequency trains ( CFT and DFT ) were applied to the quadriceps of seven
adults with
SCI and eight able - bodied participants . -
pubmed
PARTICIPANTS : Seven
individuals with
SCI ( 1 female ; age range , 25 + 6 years ) and eight age - matched able - bodied participants ( 1
female ) . -
pubmed
The updated CANMAT guidelines recommended the most second - generation antidepressants as first - line treatments for
patients with a major
depressive disorder (
MDD ) of moderate or greater severity . -
pubmed
It is recommended that antidepressant is used with monotherapy in
patients with
depression . -
pubmed
Antidepressants of different types and different mechanisms could be combined to improve the efficacy for
patients with
treatment - resistant depression (
TRD ) . -
pubmed
To prevent the
relapse and
recurrence of disease , the long - term treatment comprised of acute treatment , consolidation treatment , and maintenance treatment must be considered for all
patients . -
pubmed
AKI had developed in 47
patients ( 45.6 % ) by the second postoperative day . -
pubmed
We retrospectively evaluated
patients with operable early - stage
NSCLC who elected to receive primary SBRT , examined factors associated with SBRT , and compared overall survival after surgery and SBRT . -
pubmed
It can serve as a central component for rheumatological healthcare for
patients with
RA at various levels . -
pubmed
Therefore , we investigated the relationship between
pain and angular change of the lower extremity in
genu varus patients . -
pubmed
Standing whole - lower - leg plain radiographs of 127 legs ( 77
patients ) with > 4 of
genu varum were evaluated . -
pubmed
Trimeresurus albolabris snakebite treatment implications arising from ontogenetic venom comparisons of anticoagulant function , and antivenom efficacy . -
pubmed
Given that
coagulotoxicity is the primary serious pathology in
T. - pubmed
albolabris envenomations , we conclude that Thai
Red Cross Green Tree Pit Viper Antivenom is a valid treatment for
envenomations by this species , regardless of age or sex of the offending snake . -
pubmed
Characterizing Static and Dynamic Fractional Amplitude of Low - Frequency Fluctuation and its Prediction of Clinical Dysfunction in
Patients with Diffuse
Axonal Injury . -
pubmed
RATIONALE AND OBJECTIVES : Recently , advanced magnetic resonance imaging has been widely adopted to investigate altered structure and functional activities in
patients with
diffuse axonal injury (
DAI ) , this
patient presumed to be caused by shearing forces and results in significant neurological effects . -
pubmed
MATERIALS AND METHODS : In this study , static and dynamic fractional amplitude of low - frequency fluctuation ( fALFF ) , an improved approach to detect the intensity of intrinsic neural activities , and their temporal variability were applied to examine the alteration between
DAI patients ( n = 24 ) and healthy controls ( n = 26 ) at the voxel level . -
pubmed
Then , the altered functional index was used to explore the clinical relationship and predict dysfunction in
DAI patients . -
pubmed
RESULTS : We discovered that , compared to healthy controls ,
DAI patients showed commonly altered regions of static fALFF , and its variability was mainly located in the left cerebellum posterior lobe . -
pubmed
More important , the increased temporal variability of dynamic fALFF in the left caudate could predict the severity of the Glasgow Coma Scale score in
DAI patients . -
pubmed
Liver transplantation for
fulminant herpes simplex hepatitis in a
patient treated with
adalimumab for
chronic pouchitis . -
pubmed
The aim of the current study was to review articles published in the years 2017 - 2018 and create a list of the most important and strongest non - conventional factors that could be used in the future assessment of the prognosis of
patients with
adenocarcinoma and
squamous cell carcinoma of the lung who can not undergo current targeted therapy . -
pubmed
The selected molecular factors exhibit the potential to be used in the treatment of
patients with specific problematic
lung cancer , and may contribute to setting recommendations for the diagnosis , prognosis and treatment of individual
patients with
lung cancer . -
pubmed
Accumulating data from both
humans and experimental animal models suggests that
PVAT dysfunction is potentially linked to
cardiovascular diseases , and associated with augmented
vascular inflammation , oxidative stress , and arterial remodeling . -
pubmed
Both soil and foliar
Se and
Si applications significantly alleviated
Cd toxicity by regulation of
Cd transport genes , as reflected by increased the grain yield and antioxidant enzymes activities , and reduced
MDA in
wheat tissues . -
pubmed
Cinnamaldehyde /
eugenol blend did not show any
cytotoxic effect ( IC50 > 1000 mug / ml ) in
human normal keratinocyte cell line . -
pubmed
Facial Morphological Changes Following Denture Treatment in
Children with
Hypohidrotic Ectodermal Dysplasia . -
pubmed
Purpose : The purpose of this study was to characterize the facial morphology of Chinese
children with
hypohidrotic ectodermal dysplasia (
HED ) and quantify facial changes after prosthetic treatment . -
pubmed
Methods : 3 - D facial images of 12
HED children were taken and their facial morphology was compared against 28 healthy controls . -
pubmed
Conclusions : The facial morphology of Chinese
children with
hypohidrotic ectodermal dysplasia differs significantly from healthy children , creating a more concave facial profile . -
pubmed
The Relationship between
Diabetes Mellitus Type II and
Intervertebral Disc Degeneration in Diabetic
Rodent Models : A Systematic and Comprehensive Review . -
pubmed
The number of
diabetic patients grows constantly worldwide . -
pubmed
T2DM rodent models provide versatile tools to study this interrelation . -
pubmed
, experimental study with clearly outlined methods investigating
IVDD in
diabetic rodent models ) and exclusion ( e.g. -
pubmed
, non - experimental ) criteria , we included 23 studies from 1992 to 2020 analyzing different aspects of
IVDD in
diabetic rodents , such as on pathogenesis ( e.g. -
pubmed
One strong , 18 moderate , and three mild evidences of the link between
DM and
IVDD in
rodents were found , while only one study has not approved this link . -
pubmed
Further studies are required to confirm these results in
dyspnoeic dogs . -
pubmed
Since 2010 ,
porcine epidemic diarrhea virus (
PEDV ) has received global attention with the emergence of variant
strains characterized with high pathogenicity . -
pubmed
Relationship between regional myocardial
procainamide concentration and regional myocardial blood flow during
ischemia in the
dog . -
pubmed
The results of conservative therapy in 160
patients with so - called
idiopathic facial paralysis are reported . -
pubmed
In incomplete
paralysis the number of
patients restored to health was about 96.1 % , and 93.3 % incomplete
paralysis . -
pubmed
Inhibitory effect of
sarcophytol A on development of spontaneous
hepatomas in
mice . -
pubmed
The inhibitory effect of
sarcophytol A , a
cembrane - type
diterpene isolated from a
marine soft coral ,
Sarcophyton glaucum , on development of spontaneous
hepatomas was investigated in
C3H / HeNCrj mice . -
pubmed
At week 65 of the experiment ,
mice were examined for
hepatomas . -
pubmed
The percentages of
hepatoma - bearing
mice of the subgroup with three or more
tumors and the
tumor diameters of the group treated with
sarcophytol A were smaller than those of the control group . -
pubmed
These results suggest that
sarcophytol A inhibits the development of spontaneous
hepatomas without toxicity , and should be considered as a possible
cancer chemopreventive agent for
hepatomas in
humans . -
pubmed
Three out of 4 hybrids tested were able to form colonies in soft agar and to grow as
tumors in either nude or ( BALB / c x C3H ) F1
mice , albeit at a reduced rate . -
pubmed
Between 40 and 43
Haemophilus influenzae isolates obtained from Greece , Lebanon , Israel and Morocco respectively ( a total of 167
strains ) were analysed for prevalence of resistance to six different drugs . -
pubmed
A comprehensive clinicoimmunological examination was made of 105 male
patients aged 35 - 65 years who suffered from
coronary heart disease . -
pubmed
Immunomodulating therapy is regarded as an additional approach to the treatment of
CHD patients with marked lipoprotein sensitization . -
pubmed
Twelve healthy male
volunteers participated in four experimental occasions during each of which they were dosed with one of the following anti -
psychotic drugs :
chlorpromazine ( 50 mg ) ,
haloperidol ( 3 mg ) ,
sulpiride ( 400 mg ) and placebo . -
pubmed
Eighteen
MS patients with visual acuity of 20/30 or better and without recent
visual complaints , and 14 age- and sex - matched controls were studied by TV pupillography . -
pubmed
It is concluded that
MS patients with preserved visual acuity have only discrete autonomic
pupillary disturbances and that the PLR delay is related to
disease progression . -
pubmed
Histomorphometry was performed on representative trephine biopsies of the bone marrow on admission of 50
patients ( 21 male , 29 female - age 67 years ) with so - called
primary osteomyelofibrosis /- sclerosis (
OMF ) not preceded by any other subtype of chronic
myeloproliferative disorders . -
pubmed
Secondly , we concentrated on a discrimination of
OMF patients into two subgroups according to bone marrow morphology and clinical variables . -
pubmed
We describe a
patient with
carcinoma of a fallopian tube initially presenting with
oliguric renal failure . -
pubmed
In this study , large numbers of
hybridomas ( produced by syngeneic immunization with
B16 mouse melanoma and fusion with
NS-1 myeloma cells ) were screened for the production of antibodies that affected morphology and growth of animal and
human tumor cells in vitro . -
pubmed
In vivo both antibodies reduced the number of growing
lung tumors of
B16 melanoma in
C57BL / 6 mice by 70%-90 % when injected 3 days after the
tumor cells . -
pubmed
[ Development of
anemia in newborn
animals after acute
hypoxia ] . -
pubmed
[ Cytological assessment of the action of
Mentadent C toothpaste on the gingival epithelium in
patients with
periodontal diseases ] . -
pubmed
[ Results of using autologous and demineralized allogeneic bone transplants in reconstructive operations on the mandible in
children with the
syndrome of the first and second branchial arches ] . -
pubmed
A comparative clinico - roentgenological assessment of results of transplantation of auto- and allogenic demineralized transplants in reconstructive operations on the mandible was made in 58
children with the
syndrome of the first and second branchial arches aged from 1 to 14 years . -
pubmed
Because of autodigestion of
lactose by its endogenous
bacteria , the
lactose in yogurt is better absorbed than other sources of
lactose in
lactase - deficient subjects . -
pubmed
Between 1981 and 1985 , 27
patients with
aplastic anemia have been treated by immunosuppression with
antilymphocyte globulin and
prednisolone or allogeneic bone marrow transplantation . -
pubmed
Long - term follow - up of
dermatitis herpetiformis in
children . -
pubmed
Treatment with a gluten - free diet alone led to a reversal of the
intestinal abnormality in 100 % of our
children and to the disappearance of
cutaneous lesions in 82 % of reported cases . -
pubmed
[ Assay of leucocyte adherence inhibition in
patients with
ovarian cancer ] . -
pubmed
Is
hyperventilation a physiologically significant stimulus for
prostaglandin release in the
human pulmonary vascular bed ? -
pubmed
The influence of
hyperventilation on the pulmonary
prostaglandin (
PG ) release was studied in healthy
volunteers . -
pubmed
The increased ventilation did not alter the arterio - venous PG concentration differences suggesting that
hyperventilation accompanying the activation of chemoreceptors is not a physiologically significant stimulus for the pulmonary
PG release in
man . -
pubmed
The majority of
infections were caused by
Pseudomonas ,
Enterobacter ,
Klebsiella , and
Escherichia coli . -
pubmed
Overall ,
aztreonam was superior to
tobramycin for treatment of
pneumonia due to susceptible gram - negative bacteria in these critical care
patients . -
pubmed
[ Nephron function in acute
glycerol - induced
renal insufficiency in
rabbits ] . -
pubmed
Venous and nerve invasion as prognostic factors in postoperative survival of
patients with resectable
cancer of the rectum . -
pubmed
The histopathologic and clinical findings in 682
patients with
carcinoma of the rectum have been analyzed . -
pubmed
The five - year survival rate for
patients with resectable
tumors was 49 per cent . -
pubmed
When venous invasion was observed ,
liver metastases developed over three times as frequently in these
patients as when
metastases were not demonstrated . -
pubmed
Diminished renal function in the geriatric group may explain the slower elimination of the drug in the old
subjects . -
pubmed
Both groups were inferior to 10 controls , and frontal - lesioned
patients were inferior to those with
posterior lesions . -
pubmed
OBJECTIVES : To examine the effects of drug treatment on laboratory exercise tests in relation to measures of daily activity in
patients with chronic
heart failure . -
pubmed
The pedometer scores of the
patients with
heart failure were greatly reduced compared with those of the controls ( 258 ( 45 ) x 10(2 ) v 619 ( 67 ) x 10(2 ) steps / week , P & lt ; 0.001 ) and after 12 weeks of treatment were unchanged ( 261 ( 42 ) x 10(2 ) steps / week ) . -
pubmed
CONCLUSIONS : These data confirm the need to use different exercise protocols when assessing the benefits of drug treatment in
patients with chronic
heart failure . -
pubmed
BACKGROUND : Reports have implied
etoposide as the cause of
secondary leukaemia in
patients treated for
germ cell cancer . -
pubmed
PATIENTS AND METHODS : Between 1979 and 1992 , 679 male
patients with
germ cell cancer received
etoposide containing chemotherapy . -
pubmed
RESULTS : Six of 679
patients developed
acute myeloid leukaemia ( relative risk 150 ; CI : 55 - 326 ) . -
pubmed
None of these
patients had a primary
mediastinal germ cell tumour and only 1
patient received previous radiotherapy . -
pubmed
CONCLUSION : The benefit of
etoposide containing protocols outweigh the risk of
leukaemia in
patients with intermediate or high risk disease , however in
patients with good risk disease non -
etoposide containing protocols should be explored . -
pubmed
These data indicate that there is a specific risk to naming after dominant ATL for
adult temporal lobe epilepsy (
TLE )
patients with a left hemisphere focus and the absence of an early risk factor for the development of
seizures . -
pubmed
A 35 - year - old
male presented with
trigeminal neuralgia associated with
venous angioma at the root entry zone . -
pubmed
The possibility of a
venous anomaly should be considered in younger
patients with
trigeminal neuralgia . -
pubmed
We report the establishment of a
human fetal osteoblast cell line derived from biopsies obtained from a
spontaneous miscarriage . -
pubmed
Results of this study provide further information concerning clinical use of
MMI in
dogs and may contribute to better understanding of the mechanism of
MMI protection against chemically induced
nephrotoxicosis . -
pubmed
Human individuals were hypothesized to use the same pattern of jaw muscle activity to produce the same
bite force . -
pubmed
Effect of
ketoprofen on
Escherichia coli heat - stable enterotoxin - induced
diarrhea of calves . -
pubmed
To evaluate the effect of
ketoprofen on fecal output during
secretory diarrhea , 16 calves were given approximately 200 micrograms of heat - stable
Escherichia coli enterotoxin by suckling on 2 occasions . -
pubmed
[ Methods for the curative treatment of
pleural empyema with
bronchial fistulae in
patients with
pulmonary tuberculosis ] . -
pubmed
In contrast to non - specific
pleural empyemas in which closed sanitization is sufficiently beneficial , an early application of
thoracostoma is essential for
patients with
tuberculous pleural empyema with
bronchial fistulas . -
pubmed
This has been supported by the comparative analysis of the outcomes of radical operations in 139
patients following closed and open management of the empyemic cavity in
pulmonary tuberculosis . -
pubmed
Convulsions induced by
methyl beta - carboline-3 - carboxylate in
mice : effects of preceding saline injections . -
pubmed
or of saline were studied in nine inbred
mouse strains . -
pubmed
Detection of occult
lymphoma in the peripheral blood and bone marrow of
patients with untreated early - stage and advanced - stage
follicular lymphoma . -
pubmed
PATIENTS AND METHODS : Bone marrow and peripheral - blood samples from 28 newly diagnosed
patients with
follicular lymphoma referred from several different medical centers were assessed . -
pubmed
RESULTS : Morphologic assessment of the bone marrow was positive for
lymphoma cells in 11 of 28
patients . -
pubmed
PCR amplification of t(14;18 ) breakpoint DNA detected
lymphoma cells in 17 of 24
patients assessed . -
pubmed
Lymphoma cells were found in the bone marrow and/or peripheral blood as frequently in early - stage
patients as in advanced - stage
patients . -
pubmed
CONCLUSION : PCR amplification of t(14;18 ) breakpoint DNA together with morphologic assessment had the highest yield of detecting
lymphoma cells in the bone marrow and/or peripheral blood of our population of newly diagnosed
patients with
follicular lymphoma . -
pubmed
Twenty - two
patients with
cerebral vascular accident (
CVA ) , clinically confirmed by head computed tomography , were observed for symptoms of the
reflex sympathetic dystrophy syndrome (
RSDS ) . -
pubmed
All
patients received triple phase bone scans ; 16 scans were positive for
RSDS . -
pubmed
Patients with negative scans had no symptoms of
RSDS . -
pubmed
Five
patients with positive scans had
RSDS symptoms at the time of bone scanning . -
pubmed
Seven of 11
patients with positive scans but no symptoms of
RSDS at the time of bone scan developed symptoms of
RSDS within six months . -
pubmed
Considering only those
patients who were asymptomatic for
RSDS at the time of bone scanning , we found bone scanning to be a good predictor for the future development of clinical
RSDS . -
pubmed
We found the correlation between positive bone scans and the subsequent development of clinical
RSDS in previously asymptomatic
individuals to be statistically significant ( p & lt ; 0.05 ) . -
pubmed
We conclude that bone scans may be a good predictor of
patients at risk for developing clinical
RSDS after
CVA . -
pubmed
OBJECTIVE : To examine the use of oral
ciprofloxacin and parenteral antimicrobials in the treatment of acute
infection ( respiratory tract , urinary tract , blood ) in hospitalized
patients , with particular reference to severity of
infection , outcome , and associated economic implications of each treatment . -
pubmed
RESULTS : Four hundred eighty - five
patients were enrolled for analysis ; 208 of the patients had
respiratory tract infection , 112 had
urinary tract infection , 138 had
septicemia , and 27 had mixed
infections . -
pubmed
Sepsis scores were applied to 152
patients receiving oral
ciprofloxacin and 333
patients receiving parenteral antimicrobials and yielded mean scores of 5.9 ( SD 3.1 , range 1 - 13 ) and 8.7 ( SD 4.2 , range 1 - 22 ) , respectively . -
pubmed
Of 485
patients , 188 were paired according to
sepsis score results and route of administration . -
pubmed
Mouse infections with the pinworm ,
Syphacia obvelata , were evaluated as a potential model of
human enterobiasis . -
pubmed
To find out whether a long - term physical illness since childhood increases the risk of experiencing psychological and
somatic symptoms , we interviewed a group of 487
patients aged 20 - 25 years and compared these findings to 211 controls . -
pubmed
A prospective study of quantification of
urinary incontinence and quality of life in
patients undergoing radical retropubic prostatectomy . -
pubmed
OBJECTIVES : To prospectively evaluate the level of
urinary incontinence and its impact on quality of life in
patients undergoing radical retropubic prostatectomy . -
pubmed
METHODS :
Patients completed a 24 - hour pad test together with an
incontinence and quality - of - life questionnaire before and after surgery . -
pubmed
The 24 - hour pad test demonstrated that 87 % of
patients had some
incontinence at 1 month and 63 % at 6 months after surgery . -
pubmed
Seventy - five
patients with
malignant tumors of the upper jaw and nasal cavity have received combination therapy . -
pubmed
METHODS : To determine whether a 100 mg alternate day dose of
aspirin given in regular and enteric coated formulations for a 2 - week period is sufficient to inhibit platelet function in
men and
women , a randomized , double - blind , placebo - controlled trial was conducted among 22 healthy
volunteers evaluating the effects of these preparations on
platelet aggregation induced by
arachidonic acid ,
adenosine diphosphate , and
epinephrine , and on plasma concentrations of
thromboxane and
prostacyclin . -
pubmed
The clinical efficacy of this dose and formulation of
aspirin is being tested in the ongoing
Women 's Health Study , a randomized , double - blind , placebo - controlled trial of 40000 female health professionals designed in part to assess the benefits and risks of 100 mg alternate day
aspirin in the primary prevention of
cardiovascular disease . -
pubmed
Cell surface
carbohydrates as prognostic markers in
human carcinomas . -
pubmed
Tumour - associated
carbohydrate changes have been used in the diagnosis of
human cancers . -
pubmed
STUDY DESIGN : A retrospective study of 1263
patients with symptomatic
yeast vaginitis confirmed by culture techniques was performed . -
pubmed
MATERIALS AND METHODS : Between June 1995 and January 1996 , 2
patients with a solitary metachronous contralateral
adrenal metastasis from
renal cell cancer were evaluated . -
pubmed
Both
patients had undergone radical nephrectomy for localized
renal cancer 5 years previously . -
pubmed
Neither
patient had recurrent
cancer at 11 and 16 months of followup . -
pubmed
CONCLUSIONS : Laparoscopic adrenalectomy for
metastatic renal cell cancer was performed successfully in 2
patients . -
pubmed
However , the short - term benefits to the
patient of earlier ambulation , decreased
pain , minimal incisions and shortened
convalescence must be weighted against the as yet unknown long - term ( 5 years ) results . -
pubmed
High - speed rotational atherectomy of
human coronary stenoses : acute and one - year outcomes from the New Approaches to Coronary Intervention ( NACI ) registry . -
pubmed
A total of 525
patients with 670 lesions treated with
RA form the substrate of this report . -
pubmed
MI occurred in 6 % of
patients , consisting predominantly of non - Q - wave
MI ( 5 % ) . -
pubmed
At 1 - year follow - up , 27 % of
patients required target lesion revascularization and 30 % had experienced
death , Q - wave
MI , or target lesion revascularization . -
pubmed
Beta - carotene concentration in buccal mucosal cells with and without
dysplastic oral leukoplakia after long - term
beta - carotene supplementation in
male smokers . -
pubmed
Altogether 17
subjects showed
oral leukoplakia , 7 had
dysplasia . -
pubmed
In these 7
subjects , the BC concentration in buccal mucosal cells did not differ statistically significantly compared to subjects with only
hyperkeratosis ( n = 10 ) ( F - test , P = 0.74 ) . -
pubmed
There was no evidence to support an association between cellular BC concentration and
precancerous lesions among the few
subjects having them in their oral mucosae . -
pubmed
No difference was found in terms of
intraoperative complications , proportion of
patients who required transfusion ,
endometritis ,
sepsis , febrile morbidity , and
urinary tract infections . -
pubmed
The second was a prospective study of 39
patients ( 19F , 20 M ) followed for a median of 30 months ( range 5 - 64 months ) following either allogeneic ( allo , n = 29 ) or autologous ( auto , n = 10 ) BMT to determine if
bone loss was related to treatment of
graft versus host disease (
GVHD ) with glucocorticoids and
cyclosporine A ,
high bone turnover rates , or
hypogonadism . -
pubmed
Urinary
bone resorption markers were higher than in normal gender- and age - matched control
subjects . -
pubmed
Glucocorticoid - pretreated
women with
amenorrhoea had lower lumbar spine ( LS ) and FN BMDs than eumenorrheic
women and
women receiving HRT . -
pubmed
Avascular
necrosis of the femoral head occurred in four , and
vertebral and rib fractures occurred in one of the allo BMT
patients , but in no auto BMT
patients . -
pubmed
In conclusion , BMT
recipients are at risk of
osteoporosis secondary to
bone loss associated with their underlying illness and/or chemotherapy , particularly in female autograft recipients , and in allograft recipients secondary to
GVHD and its treatment . -
pubmed
Efficacy and safety of self - start therapy in
women with recurrent
urinary tract infections . -
pubmed
PURPOSE : We evaluated the efficacy of self - start therapy in
women with recurrent
urinary tract infections . -
pubmed
MATERIALS AND METHODS :
Women with recurrent
urinary tract infections received a dip slide urine culture kit and 6 tablets of
norfloxacin ( 400 mg . ) -
pubmed
At each symptomatic
urinary tract infection episode the
patient performed a culture and initiated therapy . -
pubmed
Six
women followed for 74 months were asymptomatic and 9 followed for 103 months had no
infections . -
pubmed
A total of 28
women followed for 355 months had 84 symptomatic episodes and 25 had 67
urinary tract infections . -
pubmed
Patients had symptomatic episodes at a rate of 2.8 per patient - year ( range 0 to 9 ) and
infections at a rate of 2.3 per patient - year ( range 0 to 9 ) . -
pubmed
A 63 - year - old
female was transferred to our hospital suffering from
gait disturbance and
dysarthria . -
pubmed
An economic analysis of an aggressive diagnostic strategy with single photon emission computed tomography myocardial perfusion imaging and early exercise stress testing in emergency department
patients who present with
chest pain but nondiagnostic electrocardiograms : results from a randomized trial . -
pubmed
RESULTS : We enrolled 46
patients , 9 with acute
myocardial infarctions . -
pubmed
CONCLUSION : An ED
chest pain diagnostic strategy incorporating acute resting
( 99m ) Tc tetrofosmin SPECT imaging and early exercise stress testing may lead to reduced in - hospital costs and decreased length of stay for
patients with acute
chest pain and nondiagnostic ECGs . -
pubmed
SUBJECTS : 108
patients with single uncomplicated
hydatid cysts who were operated on in two clinics between 1990 and 1995 . -
pubmed
CONCLUSION : Introflexion and omentoplasty after partial cystectomy for a single uncomplicated
hydatid cyst caused significantly fewer complications than external drainage , and
patients left hospital sooner . -
pubmed
BACKGROUND : Multivitamin supplementation in pregnant
women may reduce the risks of
cardiovascular defects ,
oral clefts , and
urinary tract defects in their infants . -
pubmed
The use of
Hirudo medicinalis in
nipple - areolar congestion . -
pubmed
However , its place in the management of anticipatory and delayed
vomiting in
cancer treatment and as a rescue antiemetic in surgical
patients needs to be further explored . -
pubmed
Furthermore , recent
animal and
human research also reflects its possible novel application in the treatment of other disease states , such as
alcoholism ,
cocaine addiction ,
opioid withdrawal syndrome ,
anxiety disorders ,
gastrointestinal motility disorders ,
Tourette ' s syndrome and
pruritus . -
pubmed
Electrical foot -
shock stress induced both
DOPA and
dopamine release , measured by microdialysis , from the nucleus accumbens in freely moving
rats . -
pubmed
PURPOSE : The aim of this study was to assess the value of endoanal ultrasound ( EUS ) in comparison to anal manometry and operative findings in
patients suffering from
faecal incontinence . -
pubmed
Patient history , localisation of
sphincter defects and therapeutic modalities were analysed . -
pubmed
METHODS : Over a 3 - years period , 92
patients with
faecal incontinence were investigated by endoanal ultrasound . -
pubmed
CONCLUSION : Endoanal ultrasound is a very sensitive method for localizing
anal sphincter defects and is mandatory in the assessment of
patients with
faecal incontinence . -
pubmed
Differences in risk factors among clinical types of
oral candidiasis in the Women 's Interagency
HIV Study . -
pubmed
STUDY DESIGN : A cross - sectional analysis of baseline data for 577
human immunodeficiency virus ( HIV )- seropositive and 152
HIV - seronegative women from the Women 's Interagency
HIV Study was conducted . -
pubmed
HIV seropositivity was associated with
PC ,
EC , and
DS , but not AC . -
pubmed
Analysis of the
cytotoxicity and
mutagenicity of drinking water disinfection by - products in
Salmonella typhimurium . -
pubmed
We analyzed the
cytotoxicity and
mutagenicity of the drinking water disinfection by - products ( DBPs )
bromoform ( BF ) ,
bromoacetic acid ( BA ) ,
dibromoacetic acid (
DBA ) ,
tribromoacetic acid (
TCA ) ,
chloroform ( CF ) ,
chloroacetic acid ( CA ) ,
dichloroacetic acid (
DCA ) ,
trichloroacetic acid (
TCA ) ,
3 - chloro-4 -( dichloromethyl )- 5 - hydroxy-2 [ 5H ]- furanone ( MX ) , and
potassium bromate (
KBrO3 ) in
Salmonella typhimurium strains
TA98 ,
TA100 , and
RSJ100 + /- S9 . -
pubmed
TA100 - S9 was the most sensitive
strain for these
DBPs . -
pubmed
METHODS :
Subjects were 24 premenopausal
women ( mean age , 39.5+/-9.4 years ; range , 32 - 52 years ) with
uterine leiomyomas . -
pubmed
For the
radio - carpal arthrosis ,
injuries are often present for elderly woman ( P & lt ; 0.01 ) and young
man ( P & lt ; 0.05 ) . -
pubmed
Epstein - Barr virus (
EBV ) is the major triggering factor producing
hemophagocytic syndrome or
hemophagocytic lymphohistiocytosis (
HLH ) . -
pubmed
In patients with
EBV - HLH , the
EBV - infected T cells or natural killer ( NK ) cells are mostly mono- or oligo - clonally proliferating , where
hypercytokinemia plays a major role and causes
hemophagocytosis , cellular damage and dysfunction of various organs . -
pubmed
Arachidonic acid ( AA)-induced
cytotoxicity was evaluated in leukocytes : the
human leukemia cell lines HL-60 ,
Jurkat and
Raji and in
rat lymphocytes . -
pubmed
The recognition and invasion of
human erythrocytes by the most lethal
malaria parasite
Plasmodium falciparum is dependent on multiple ligand - receptor interactions . -
pubmed
One
patient developed a necrotizing
fasciltis , and in two others , migration of the tube was observed . -
pubmed
A - THIB " was defined as the absolute difference in integrated backscatter between the left ( subendocardial ) and right ( subepicardial ) ventricular halves of the myocardium in the septum and posterior wall , and was measured in 11
patients with
PSS and 10 age- and sex - matched healthy participants . -
pubmed
A - THIB in
patients with
PSS was higher than that in healthy participants ( 1.3 + /- 1.3 vs 4.0 + /- 1.4 dB for the septum and 1.1 + /- 0.7 dB vs 2.8 + /- 0.4 dB for the posterior wall ; mean + /- SD , respectively , P & lt;.0005 ) . -
pubmed
The patient was a 57 - year - old Japanese
man who had moderate
splenomegaly , and who had undergone splenectomy for improvement of severe
autoimmune hemolytic anemia and to rule out
malignancy in the spleen . -
pubmed
Monoclonal antibodies ( MoAbs ) are increasingly used in the treatment of
patients with
hematological malignancies and
autoimmune diseases . -
pubmed
Tourniquet shock in
rats ; reversibility in the terminal phase . -
pubmed
Some cultural characteristics of
Staphylococcus aureus strains from
superficial skin infections . -
pubmed
Phosphate clearance and tubular reabsorption of
phosphate in
patients with
parathyroid disorders and
renal failure . -
pubmed
Including
patients with
diabetes mellitus or coronary artery bypass grafting decreases the association between heart rate variability and mortality after
myocardial infarction . -
pubmed
BACKGROUND : Decreased heart rate variability ( HRV ) is often assumed to be associated with mortality in all
patients after
myocardial infarction (
MI ) , independent of clinical factors or time after
MI . -
pubmed
Patients were 71 + /- 120 days after
MI . -
pubmed
A total of 735 pre - therapy tapes were analyzed in
patients who had
ventricular premature contractions (
VPCs ) suppressed on the first treatment . -
pubmed
The association of clinical and demographic factors and 24 - hour , daytime , and nighttime HRV to mortality in all
patients , patients without coronary artery bypass graft ( CABG ) surgery between the qualifying
MI and the Holter monitoring , and patients with neither CABG nor
diabetes mellitus was determined with univariate Cox regression analysis . -
pubmed
Sleep problems such as nocturnal awakening and abnormality in the percentage of
rapid eye movement ( REM ) sleep are frequently observed in
patients with
SMS , and several medications have been administered to improve the
sleep disorders . -
pubmed
Two
dogs were found to have clinical , histopathological and immunofluorescent findings compatible with a diagnosis of
canine discoid lupus erythematosus . -
pubmed
The effect of
acetylshikonin isolated from
Lithospermum canescens roots on
tumor - induced cutaneous angiogenesis . -
pubmed
roots , in a daily dose of 200 microg for 3 days , inhibited cutaneous angiogenesis induced by L-1
sarcoma cells in
Balb / c mice . -
pubmed
[ Awareness of disease in
dementia : preliminary results in
patients with mild and moderate
Alzheimer ' s disease ] . -
pubmed
RESULTS : Awareness of disease and its consequences were present in 66.7 %
patients with mild
AD ( n=18 ) . -
pubmed
A 61 - year - old
woman presented with a huge
hemangioma on the right ventricle . -
pubmed
Four
patients experienced painful
paresthesias and 3
patients had accidental punctures of axillary vessels . -
pubmed
Assessing the clinical significance of drug interactions with
fluorouracil in
patients with
colorectal cancer . -
pubmed
Phenotypic viral susceptibility to SPD754 and five other NRTIs was tested using the PhenoSense
HIV assay and expressed as median fold - change compared with a reference
strain . -
pubmed
In part 1 ( 6 weeks ) , 102
patients ( & gt ; or = 12 years old ) with
hemophilic arthropathy were randomized to receive 90 mg
etoricoxib once daily or placebo ( 1:1 ratio ) . -
pubmed
Efficacy end points included
Patient Assessment of
Arthropathy Pain ,
Patient Global Assessment of
Arthropathy Disease Status , and Investigator Global Assessment of
Arthropathy Disease Status . -
pubmed
There was no significant difference between the blood donors and the patients with
hepatitis B as regards virological markers , including viral load , when the
HBV genotype was taken into account . -
pubmed
Possible involvement of oxidative stress in
dicyclanil - induced
hepatocarcinogenesis in
mice . -
pubmed
THE MEASUREMENT AND METABOLISM OF
THIAMIN AND OF A
PYRIMIDINE STIMULATING YEAST FERMENTATION FOUND IN THE BLOOD CELLS AND URINE OF
PATIENTS WITH
LEUKEMIA . -
pubmed
We present six
patients , each of whom had extensive
fractures of the floor of the orbit that extended posteriorly to its anatomical limit . -
pubmed
Abnormalities in the susceptibility of certain cells to receptor - induced
death are known to lead to certain
human diseases ( e.g. -
pubmed
AIM : To analyze various oxidative stress parameters in the saliva and serum of
patients with
chronic renal failure (
CRF ) and/or
diabetes mellitus (
DM ) , and to compare them in dialytic vs. pre - dialytic
patients . -
pubmed
METHOD : 50 consenting
patients were divided into five subgroups of
patients : severe
CRF ( dialytic ) without
DM , severe
CRF ( dialytic ) with
DM , mild
CRF ( pre - dialytic ) without
DM , mild
CRF ( pre - dialytic ) with
DM , and with
DM but without
CRF ( controls ) . -
pubmed
Relative role of left ventricular geometric remodeling and of morphological and functional myocardial remodeling in the transition from compensated
hypertrophy to
heart failure in
rats with
supravalvar aortic stenosis . -
pubmed
OBJECTIVE : To evaluate the relative contribution of left ventricular ( LV ) geometric remodeling and of morphological and functional myocardial changes in
rats with induced
supravalvar aortic stenosis (
SAS ) , in the transition from compensated
hypertrophy to
congestive heart failure (
CHF ) . -
pubmed
INTRODUCTION AND OBJECTIVES : In the second part of an analysis of a 10 - year period of treating
oral cancer patients , the focus was the efficiency of treatment ,
recurrence rates and survival . -
pubmed
PATIENTS AND METHODS : From 1485
patients with
oral and maxillofacial malignant tumours , 1072 cases could be evaluated . -
pubmed
RESULTS : From all
patients studied , 811 underwent surgical treatment alone , the mean
recurrence rate was 23 % . -
pubmed
We reviewed the incidence and the impact of
posttransplant lymphoproliferative disorders (
PTLDs ) on
patient survival among a consecutive series of 255 patients . -
pubmed
Olfactory dysfunction is a prominent symptom in
Parkinson ' s disease (
PD ) and found in about 70 - 100 % of
patients . -
pubmed
We suggest that the increase of dopaminergic cells in the olfactory bulb is responsible for the
hyposmia in
PD patients . -
pubmed
Are
animals autistic savants . -
pubmed
Apoptosis of
human pancreatic cancer cells induced by
Triptolide . -
pubmed
METHODS :
Human pancreatic cancer cell line
SW1990 was cultured in DMEM media for this study . -
pubmed
Flow cytometry and TUNEL assay were used to detect the apoptosis of
human pancreatic cancer cells before and after TL treatment . -
pubmed
RESULTS : TL inhibited the growth of
human pancreatic cancer cells in a dose - and time - dependent manner . -
pubmed
TL induced
human pancreatic cancer cells to undergo apoptosis with typically apoptotic characteristics . -
pubmed
TUNEL assay showed that after the treatment of
human pancreatic cancer cells with 40 ng / mL TL for 12 h and 24 h , the apoptotic rates of
human pancreatic cancer cells increased significantly . -
pubmed
CONCLUSION : TL is able to induce the apoptosis in
human pancreatic cancer cells . -
pubmed
( Jarilla ) plants exhibited a pronounced
cytotoxic effect by arresting cell viability at a level of 35 % against the
MCF-7 cell line , a
human breast adenocarcinoma , while only a weak
cytotoxic effect was observed for the aqueous extract . -
pubmed
Previous reports have stated that such
optic disc hemorrhages are associated with
intrapapillary bleeding largely in
patients of Asian origin who are visually symptomatic from this process . -
pubmed
We have encountered
patients with
PSH who have clinical features that differ from those described in these reports . -
pubmed
Medical records of 10
patients with isolated
peripapillary subretinal hemorrhages were reviewed for clinical characteristics and ancillary testing , including demographics , history , complete eye examination , visual fields , fundus photos , ultrasound , and
fluorescein angiography ( four
patients ) at presentation and follow - up . -
pubmed
We excluded
patients with
drusen , neovascular membranes ,
disc edema , and
intrapapillary hemorrhages . -
pubmed
RESULTS : There were 10
patients , all white
women without
visual symptoms , who had isolated , monocular , nasal , or superonasal peripapillary
subretinal hemorrhage , a
dysplastic crowded - tilted optic disc ,
myopia , and normal visual function . -
pubmed
CONCLUSIONS : We have described a benign
syndrome of isolated
PSH in crowded and tilted optic discs in myopic eyes of white
women . -
pubmed
METHOD / RESULTS : A 62 - year - old female
patient presents to the emergency department with complaints of a
bleeding vaginal mass ,
pain referred to the vaginal introitus and dysu - ria . -
pubmed
Nonetheless , given the balance of data both in cell ,
animal and
human studies , the use of
phosphate lowering strategies at earlier stages of
CKD , perhaps even prior to serum
phosphate level rising , may well be justified . -
pubmed
Spontaneous
pyopneumothorax is a very rare occurrence , even in
cancer treated
patients . -
pubmed
We report the case of a 64 year old
woman who presented with symptomatology of
gallstone disease but was radiologically shown to have a
polyp within the gallbladder . -
pubmed
We conclude that the development of cortical GABAergic neurons have exclusive features in
primates that need to be considered in order to understand pathological mechanisms leading to some neurological and
psychiatric diseases . -
pubmed
Although it is a rare
syndrome , early diagnosis and treatment prevents permanent
neurological deficits and improve
patient 's quality of life . -
pubmed
The goal of management of
dysarthria in
ALS patients is to optimize communication effectiveness for as long as possible . -
pubmed
This review summarizes the current state of knowledge on the clinical features , differential diagnosis , pathophysiology , investigations and management of
dysarthria in
ALS patients . -
pubmed
Methylmercury (
Me - Hg )
poisoning (
Minamata disease :
MD ) is one of the most severe types of disease caused by
humans to
humans in Japan . -
pubmed
INTRODUCTION :
Erythrodermic psoriasis is a rare generalized clinical presentation of
psoriasis in
children and adults . -
pubmed
CASE PRESENTATION : We present the case of a 9 - year - old native Hispanic
girl with severe
erythrodermic psoriasis associated with uncommon advanced nail and joint manifestations . -
pubmed
Increased efficacy of early spinal cord stimulation in an
animal model of
neuropathic pain . -
pubmed
Although spinal cord stimulation ( SCS ) is an established treatment for chronic
neuropathic pain ,
pain relief is still not successful in a large group of
patients . -
pubmed
Animals with
tactile allodynia received 30min of SCS . -
pubmed
Out of the 13
allodynic animals that received early SCS , 10 ( 77 % ) responded to SCS with significantly increased withdrawal thresholds , compared to 38 % in the late SCS group . -
pubmed
Early SCS treatment of
neuropathic rats is more effective as compared to the late SCS treatment . -
pubmed
RESULTS : Fourteen
patients ( 53.9 % ) had
ear - lobe keloids and 11 ( 42.3 % ) of the
patients developed the
keloid from ear - piercing . -
pubmed
On d78 , but not d135 , placental and
fetal weights were reduced ( P & lt ; 0.05 ) in NR vs. C
ewes . -
pubmed
Some epidemiological surveys have shown an increased incidence of
malignancies in
patients with
multiple Sclerosis (
MS ) . -
pubmed
The organic extract of
Periplaneta americana L. ( Dictyoptera ; Blattidae ) has been traditionally used in southwestern China as an alternative medicine against disorders such as
hepatitis ,
trauma ,
gastric ulcers ,
burns , and
heart disease . -
pubmed
The most effective cytotoxic fraction was determined by way of repeated in vitro screenings against 12 distinct cultured
human carcinoma cell lines :
Eca 109 ,
BGC823 ,
HO8910 ,
LS174 T ,
CNE ,
HeLa ,
K562 ,
PC-3 ,
A549 ,
BEL 7404 ,
HL-60 , and
KB , followed by in vivo antitumor assays of the lead fraction ( PAE60 ) . -
pubmed
PAE60 reduced
tumor growth in
S180 - bearing immunocompetent
mice by 72.62 % after 10 days following oral doses of 500 mg kg d-(1 ) compared with 78.75 % inhibition following 40 mg kg d-(1 ) of
cyclophosphamide (
CTX ) . -
pubmed
The contribution of
gliosis to diffusion tensor anisotropy and tractography following
traumatic brain injury : validation in the
rat using Fourier analysis of stained tissue sections . -
pubmed
It is hoped that this increased sensitivity will aid in the detection and prognostication in
patients with
traumatic injury . -
pubmed
We developed a method to quantify the anisotropy of stained histological sections using Fourier analysis , and applied the method to a
rat controlled cortical impact model to identify the specific pathological features that give rise to the diffusion tensor imaging changes in subacute to chronic
traumatic brain injury . -
pubmed
MATERIALS AND METHODS : We carried out a prospective observational study to determine the treatment response rate , tolerability and outcome of
patients with
cryptococcal meningitis in
HIV treated with
amphotericin B. -
pubmed
RESULTS : A total of 27
patients were diagnosed with
cryptococcal meningitis during the study period . -
pubmed
Headache ( 96.29 % ) was the single most common presenting symptom of
cryptococcal meningitis in
HIV - infected
patients , followed by
vomiting ( 77.77 % ) and
fever ( 66.66 % ) . -
pubmed
CONCLUSIONS : We found that the recommended 2 weeks induction treatment with
Amphotericin B monotherapy for
HIV patients with
cryptococcal meningitis in resource - limited settings may be suboptimal for at least one - third of the
patients . -
pubmed
Penile necrosis due to
priapism developed after circumcision in a
patient with
protein S deficiency . -
pubmed
METHODS : l Nine - year - old
boy referred from another hospital with the sequelae of the
penile ischemia with
discoloration of the penis after traditional circumcision . -
pubmed
These
animals subsequently progress to
acute leukemias . -
pubmed
Postconditioning by mild hypoxic exposures reduces
rat brain injury caused by severe
hypoxia . -
pubmed
The present study has been performed to determine whether postconditioning by mild episodes of hypobaric
hypoxia (
hypoxic postconditioning , HP ) can reduce post - hypoxic
brain injury in
rats . -
pubmed
OBJECTIVES : Determination of
lymphatic metastasis is of great importance for both treatment planning and
patient prognosis . -
pubmed
Anti - fibrotic effect of
Aliskiren in
rats with
deoxycorticosterone induced
myocardial fibrosis and its potential mechanism . -
pubmed
BACKGROUND : Distal femoral physis
fractures with displacement are rare
injuries seen in
adolescents related with high incidence of complication . -
pubmed
CASE REPORT : The case of a 14 - year - old
boy with
Salter - Harris type II displaced fracture underwent surgery with open reduction has been described . -
pubmed
CONCLUSIONS : Knowledge of classification , prognosis and methods of treatment is necessary in accurate pre- and postoperative assessment of
physial fractures in
adolescents . -
pubmed
Management of adverse events of targeted therapies in normal and special
patients with
metastatic renal cell carcinoma . -
pubmed
These biological agents have toxicity profiles that differ from those accompanying current chemotherapeutic agents , but their novelty leads to a lack of exhaustive clinical data regarding related adverse events ( AEs ) , whose symptoms may overlap with those of the
chronic illnesses of
patients with
mRCC such as
hypertension ,
hyperglycemia , and
pneumonitis . -
pubmed
Recommendations for treating these adverse events in
patients with
mRCC are usually the same as those for the general population . -
pubmed
Some groups of patients with
mRCC , such as frail , elderly
patients , and
patients with
renal or liver dysfunction , require special management of AEs . -
pubmed
RESULTS : A significant reduction in
human biting rate was recorded after the third round of IRS , specifically in Adjohoun ( 89.78 % ) , Dangbo ( 56.8 % ) and Misserete ( 93.22 % ) where an inhabitant received less than 2
bites of
An . - pubmed
Chlorpyrifos induced
testicular damage in
rats : ameliorative effect of
glutathione antioxidant . -
pubmed
CPF was administered orally , in a dose of 30 mg / kg
body weight to male
rats for 90 days , twice weekly . -
pubmed
MATERIALS AND METHODS : Twenty - eight
patients 11 months to 9 years of age presenting with
chronic constipation , with contrast enema showing dilated rectum and sigmoid colon were included in the study . -
pubmed
Ten
patients had
aganglionosis ( of which 5 had
ganglion cells present in the proximal part of speciment ) , 7 had normal histology , 7 had
hypoganglionosis , 2 had
intestinal neuronal dysplasia , one had
nerve hypertrophy and one had immature ganglia . -
pubmed
CONCLUSION : Anorectal myectomy is an effective and technically simple procedure in selected
patients with chronic refractory
constipation , for both diagnostic and therapeutic purpose . -
pubmed
Because apart from confirming
Hirschsprung ' s disease , it also therapeutically relieves symptoms in 93 % of
patients with chronic refractory
constipation . -
pubmed
EXPERIMENTAL APPROACH : We used
MRC5 human lung fibroblasts and primary pulmonary fibroblasts of
individuals with and without
COPD . -
pubmed
EXPERIMENTAL APPROACH : Right and left ventricular trabeculae from freshly explanted hearts of 5 non - beta - blocker - treated and 15
metoprolol - treated
patients with terminal
heart failure were paced to contract at 1 Hz . -
pubmed
The overall survival of
patients with
gastric cancer has increased markedly in Korea , even higher than those of developed nations in Western world . -
pubmed
OBJECTIVE : The main objective of this study was to evaluate antidepressant activity of
vanillin in
mice models of
depression . -
pubmed
Highly pathogenic
avian influenza viruses ( HPAIVs ) cause lethal
infection in
chickens . -
pubmed
Severe cases of
HPAIV infections have been also reported in mammals , including
humans . -
pubmed
In the present study , the highly pathogenic
avian influenza viruses
A / turkey / Italy / 4580 / 1999 ( H7N1 ) ( Ty / Italy ) and
A / chicken / Netherlands / 2586 / 2003 ( H7N7 ) ( Ck / NL ) and the low pathogenic
avian influenza virus (
LPAIV )
A / chicken / Ibaraki / 1 / 2005 ( H5N2 ) ( Ck / Ibaraki ) were intranasally inoculated into
chickens . -
pubmed
The recent performance of the lead
dengue vaccine in a phase 2b efficacy trial underscores
dengue vaccine development challenges . -
pubmed
METHODS : In - vitro studies using
human coronary artery endothelial cells (
HCAEC ) and ex - vivo studies using white blood cells isolated from healthy and
OSA subjects . -
pubmed
During the past few years
infections of poultry and
humans with
H7 subtypes have increased markedly . -
pubmed
In
humans , mild to fatal
infections were caused by subtypes H7N2 , H7N3 , H7N7 and
H7N9 . -
pubmed
While
infections of
humans have been associated mostly with exposure to domestic poultry ,
infections of poultry have been linked to wild birds or live - bird markets . -
pubmed
In contrast to recent cases caused by subtype H7N9 ,
human infections were usually self - limiting and rarely required antiviral medication . -
pubmed
We identified
patients who initiated antiplatelets within 14 days following discharge from hospitalizations for
myocardial infarction (
MI ) or
acute coronary syndrome . -
pubmed
We matched
patients using high - dimensional propensity scores ( hd - PSs ) and followed them for
ischemic ( i.e. -
pubmed
Phase 2 clinical trials for
tuberculosis (
TB ) treatment require reliable culture methods to determine presence or absence of
Mycobacterium tuberculosis (
Mtb ) over the course of therapy , as these trials are based primarily on bacteriological endpoints . -
pubmed
We analyze 393 specimens from 50
HIV - negative Ugandan adults with newly - diagnosed ,
pulmonary TB and high acid - fast bacillus smear grade . -
pubmed
MATERIALS AND METHODS : A prospective study of 200 consecutive newly detected highly active anti - retroviral therapy ( HAART ) naive
HIV patients admitted over a one year period was conducted . -
pubmed
Value of surgical decompression of compressed nerves in the lower extremity in
patients with painful
diabetic neuropathy : a randomized controlled trial . -
pubmed
Forty - two
patients with painful
diabetic neuropathy were included . -
pubmed
CONCLUSION : Surgical decompression of the nerves of the lower extremity can be added as a therapeutic option for
patients with painful
diabetic neuropathy who show signs of chronic
nerve compression by means of a positive Tinel or other diagnostic criteria , when
pain medication fails to reduce
pain to an acceptable standard . -
pubmed
Mouse infection studies confirmed a high - virulence capacity of these emm59 organisms . -
pubmed
Inverse dynamic analyses were conducted in
CHF patients and age- and exercise level - matched control subjects on an instrumented treadmill at self - selected treadmill walking speeds and at speeds representing +20 % and -20 % of the subjects ' preferred speed . -
pubmed
CASE PRESENTATION : This case report describes a 58 - year - old Caucasian
woman who is a cigarette smoker with a 10 - week history of
fever of unknown origin ,
night sweats and
weight loss of 12 kg . -
pubmed
METHODS : Dissection of five temporal bones of
Sus scrofa pigs obtained from UNIFESP - Surgical Skills Laboratory , removed with hole saw to avoid any
injury and stored in
formaldehyde 10 % for better conservation . -
pubmed
Better knowledge of the molecular alterations could help in the management of
patients with this type of precursor of invasive
carcinoma . -
pubmed
Cerebral aspergillosis in a
diabetic patient leading to
cerebral artery occlusion and
ischemic stroke : a case report and literature review . -
pubmed
Cerebral aspergillosis is a rare and highly fatal
hematogenous infection most commonly found in immune compromised
patients . -
pubmed
PARTICIPANTS : Thirty - one eyes of 31
patients with
FAF . -
pubmed
INTERVENTION : All
patients with
FAF who had their first PK in Helsinki University Eye Hospital between January 1 , 1990 , and August 1 , 2011 , were identified and a retrospective analysis of the
patient charts was performed . -
pubmed
CONCLUSIONS : In a minority of
FAF patients , PK improves vision . -
pubmed
From a protocol biopsy population ( n = 690 ) , we randomly selected 100
LT patients in whom the biopsy was taken 7 - 10 days after LT . -
pubmed
METHODS : 27
patients with
AD and 16 with
FTD were included . -
pubmed
METHODS : A PRoBE design study enrolled 170
patients with
lesions suspicious for
OSCC . -
pubmed
Molecular characterization of clinical isolates of
Cyclospora cayetanensis from patients with
diarrhea in India . -
pubmed
PURPOSE :
Cyclospora cayetanensis is an intestinal coccidian protozoan that has emerged as an important cause of both epidemic and endemic protracted
diarrhea worldwide . -
pubmed
Evaluation of outpatient discharge in
patients with
cutaneous melanoma . -
pubmed
OBJECTIVE : to evaluate discharge in a group of
patients with
cutaneous melanoma according to recently established criteria . -
pubmed
METHODS : we conducted an observational , cross - sectional study with 32
patients at the Hospital Universitario Clementino Fraga Filho ( HUCFF ) / Universidade Federal do Rio de Janeiro ( UFRJ ) , between 1995 and 2013 , in the following stages : IA ( 17 cases , 53.12 % ) , IB ( 4 cases , 12.5 % ) , IIA ( 3 cases , 9.37 % ) , IIC ( 1 case , 3.12 % ) , IIIB ( 1 case , 3.12 % ) , IIIC ( 3 cases , 9.37 % ) ,
melanomas in situ ( 2 cases , 6.25 % ) , Tx ( 1 case , 3.12 % ) . -
pubmed
Paan chewing ,
tobacco and
alcohol use are strong risk factors for this
cancer in India . -
pubmed
Human papillomaviruses (
HPVs ) are also related to a subset of
head and neck cancers (
HNCs ) . -
pubmed
We examined the association between oral
HPV and
oral cancer in a sample of Indian subjects participating in a hospital - based case - control study . -
pubmed
Lack of a role for
HPV infection in this study may reflect cultural or religious characteristics specific to this region in India that are not conducive to oral
HPV transmission . -
pubmed
These mutant
mice also develop
insulin resistance and are insensitive to the
glucose - regulatory effects of
estrogens . -
pubmed
Therapy - related
acute myeloid leukemia in
patients with
lymphoma : A report of four cases and review of the literature . -
pubmed
At the time of diagnosis of
t - AML , 3 of the 4
patients presented
pancytopenia , whilst the remaining patient exhibited
leukocytosis . -
pubmed
The majority of the
patients succumbed to their disease within 1 year of t -
AML diagnosis , with the exception of the
patient in case 3 , who survived following allogeneic hematopoietic stem cell transplantation ( allo - HSCT ) . -
pubmed
Based on the present findings and a review of the literature , we propose that allo - HSCT should be recommended for
patients at high risk of developing
t - AML . -
pubmed
Sympathetic Nervous System in
Patients with
Sleep Related Breathing Disorders . -
pubmed
The objectives of this brief review are to summarize : 1 ) present knowledge concerning the mechanisms , magnitude and consequences of night- and day - time sympathetic nervous system activation in
patients with these sleep - related
breathing disorders ; and 2 ) the impact on the sympathetic nervous system and on blood pressure of their specific treatment . -
pubmed
MATERIAL AND METHODS : We identified 131
patients with a histopathological diagnosis of
astrocytic tumors ( diffuse
astrocytoma ,
anaplastic astrocytoma and
glioblastoma ) . -
pubmed
Salicylate is a well - known
ototoxic drug , and we induced
tinnitus in
rats using a model of long - term
salicylate administration . -
pubmed
The gap pre -
pulse inhibition of acoustic startle test was used to infer
tinnitus perception , and only
rats in the chronic
salicylate - treatment ( 14 days ) group showed evidence of experiencing
tinnitus . -
pubmed
Staphylococcus aureus Regulatory RNAs as Potential Biomarkers for
Bloodstream Infections . -
pubmed
BACKGROUND :
Patients with frequent
premature ventricular contractions (
PVCs ) are often highly symptomatic with significantly reduced quality - of - life . -
pubmed
RESULTS : A total of 408
patients ( age 53.5 + - 15 years , 55 %
female ) undergoing ablation for
PVCs were included . -
pubmed
32 % of
patients showed a co - existing
structural heart disease . -
pubmed
In
patients without
structural heart disease , acute success was significantly higher compared with
patients with
structural heart disease ( 86 vs. 74 % , p = 0.002 ) . -
pubmed
No
patient suffered an acute
myocardial infarction ,
stroke , or major
bleeding . -
pubmed
After 12 months ' follow - up , 99 % of
patients were still alive showing a significant different mortality between
patients with
structural heart disease compared with those without ( 2.3 vs. 0 % , p = 0.012 ) . -
pubmed
Neuropathic pain (
NPP ) is the main culprit among
chronic pains affecting the normal life of
patients . -
pubmed
Then NPP
rat model was induced by sciatic nerve chronic
compression injury (
CCI ) and behavior tests were performed to analyze the
pain behaviors upon mechanical , thermal and cold stimulations . -
pubmed
Treatment of
patients with
aortic atherosclerotic disease with
paclitaxel - associated lipid nanoparticles . -
pubmed
In
rabbits ,
atherosclerotic lesion size was reduced by 65 % following LDE -
paclitaxel treatment . -
pubmed
The current study aimed to test the effectiveness of LDE -
paclitaxel on
inpatients with
aortic atherosclerosis . -
pubmed
METHODS : This study tested a 175 mg / m2 body surface area dose of LDE -
paclitaxel ( intravenous administration , 3/3 weeks for 6 cycles ) in
patients with
aortic atherosclerosis who were aged between 69 and 86 yrs . -
pubmed
A control group of 9 untreated
patients with
aortic atherosclerosis ( 72 - 83 yrs ) was also observed . -
pubmed
CONCLUSION : Treatment with LDE -
paclitaxel was tolerated by
patients with
cardiovascular disease and showed the potential to reduce
atherosclerotic lesion size . -
pubmed
To conclude , we uncovered loss of chromosome 22 in almost half of all cases with
hybrid neurofibromas /
schwannomas of
patients with multiple
peripheral nerve sheath tumors . -
pubmed
Here , we report for the first time , two
patients of fatal
liver injury due to anti - TB drugs in the presence of
alpha-1 antitrypsin deficiency . -
pubmed
Despite aggressive medical therapy and supportive care ,
patients developed
multi - organ failure and died . -
pubmed
A
tumor model of
nude mice with
HCC was established for the study of
tumor growth condition of
tumor - bearing
mice after the interference with lncRNA00673 expression . -
pubmed
Safe and Effective Standards of Care : Supporting the Administration of T - VEC for
Patients With Advanced
Melanoma in the Outpatient Oncology Setting : . -
pubmed
To date , 16
patients with locoregionally advanced
melanoma have been treated with T - VEC . -
pubmed
Currently ,
hepatocellular carcinoma (
HCC )
patients still have poor survival outcomes mainly due to the powerful mobility of
HCC cells . -
pubmed
In addition , 5 - year overall survival ( OS ) and disease - free survival ( DFS ) rates of
HCC patients with high miR-1202 expression were much better than that in low miR-1202 group . -
pubmed
A 40 - year - old
man was referred to our hospital because of severe
anemia and small intestinal
tumor revealed by computed tomography . -
pubmed
Deep neck space abscesses in
children below 5 years of age and their complications . -
pubmed
OBJECTIVES : To study the outcomes and complications of deep neck space
abscesses in
children less than 5 years of age over a period of 15 years . -
pubmed
METHODS : A retrospective analysis of
children less than 5 years of age with deep neck space
abscesses over a 15 - year period was conducted at a tertiary care centre in India . -
pubmed
All
patients underwent
surgical incision and drainage of the
abscess and pus cultures were obtained . -
pubmed
RESULTS : A total of 510
children less than 5 years of age were identified who were admitted for deep neck space
abscess over a 15 - year period . -
pubmed
The most common organism isolated in the
pus was
Staphylococcus aureus ( 21 % ) . -
pubmed
Children less than 2 years of age , and those with multiple
abscesses or
retropharyngeal abscess were more prone to complications . -
pubmed
The antioxidant , aged
garlic extract , exerts cytotoxic effects on wild - type and multidrug - resistant
human cancer cells by altering mitochondrial permeability . -
pubmed
Aged
garlic extract ( AGE ) has been shown to possess therapeutic properties in
cancer ; however its mechanisms of action are unclear . -
pubmed
In this study , we demonstrate by
MTT assay that
AGE exerts an anti - proliferative effect on a panel of both sensitive and multidrug - resistant ( MDR )
human cancer cell lines and enhances the effects of
hyperthermia ( 42 C ) on
M14 melanoma cells . -
pubmed
A cross - sectional study including 66
schizophrenia outpatients compared to 81 healthy controls was undertaken . -
pubmed
Despite the progressive nature of
Alzheimer ' s disease and other
dementias , it is observed that many
individuals that are diagnosed with
mild cognitive impairment (
MCI ) in one clinical assessment , may return back to normal cognition ( CN ) in a subsequent assessment . -
pubmed
Cardiac Effects of Hyperoxia During Resuscitation From
Hemorrhagic Shock in
Swine . -
pubmed
However , we previously showed that
hyperoxia attenuated
myocardial injury during resuscitation from
hemorrhage in
swine with
coronary artery disease . -
pubmed
In conclusion , in contrast to our previous study in
swine with
coronary artery disease ,
hyperoxia did not beneficially affect cardiac function or
tissue injury in healthy
swine , but was devoid of deleterious side effects . -
pubmed
All isolated compounds were evaluated for their
cytotoxicities against five
human cancer cell lines :
HL-60 ,
SMMC-7721 ,
A-549 ,
MCF-7 and
SW480 in vitro . -
pubmed
We recruited 50
PD patients without
dementia , no other reasons for
cognitive impairment , no condition that could influence evaluation of cognition , olfaction and taste . -
pubmed
Olfaction was worse in
PD patients with
visuospatial dysfunction , while sour and salty identification was worse in those with
MCI and
executive dysfunction , suggesting different underlying
anatomical abnormalities . -
pubmed
Mycobacterium ulcerans is the bacillus responsible for
Buruli ulcer , an
infectious disease and the third most important
mycobacterial disease worldwide , after
tuberculosis and
leprosy . -
pubmed
Indeed , a single subcutaneous injection of
mycolactone into the
mouse footpad induces a long - lasting
hypoesthesia up to 48 h. It was suggested that the long - lasting
hypoesthesia may result from the persistence of a significant amount of
mycolactone locally following its injection , which could be probably due to its slow elimination from tissues . -
pubmed
Various quantities of
mycolactone were then injected in
mouse tissue and
hypoesthesia was recorded with nociception assays over a period of 48 h. The
hypoesthesia was maximal 6 h after the injection of 4 mug
mycolactone . -
pubmed
OBJECTIVES : To investigate the preoperative prognostic value of molecular subtypes in relation to clinical information , histopathological findings , and molecular markers for
patients with
bladder cancer treated with radical cystectomy . -
pubmed
A 69 - year - old Japanese
woman was admitted to our hospital with progressive
muscle weakness and
dysphagia . -
pubmed
Recent clinical data has presented normalization of factor levels in some
patients with improvements in
bleed rate and quality of life . -
pubmed
Although long - term data is awaited , durable expression has been seen within the
hemophilia dog model with no late - toxicity or
oncogenesis . -
pubmed
Letter by Renu et al Regarding Article , " Frequency of Blood - Brain Barrier Disruption Postendovascular Therapy and Multiple Thrombectomy Passes in
Acute Ischemic Stroke Patients " . -
pubmed
Cercospora leaf
spot ( CLS ) caused by
Cercospora canescens is an important disease of
cowpea (
Vigna unguiculata ) . -
pubmed
Early - Life
Iron Deficiency and Its Natural Resolution Are Associated with Altered Serum Metabolomic Profiles in Infant
Rhesus Monkeys . -
pubmed
BACKGROUND :
Iron deficiency is the most common
nutrient deficiency in
human infants aged 6 to 24 mo , and negatively affects many cellular metabolic processes , including energy production , electron transport , and oxidative degradation of toxins . -
pubmed
OBJECTIVES : The objective was to determine how
iron deficiency in infancy alters the serum metabolomic profile and to test whether these effects persist after the resolution of
iron deficiency in a
nonhuman primate model of spontaneous
iron deficiency . -
pubmed
METHODS : Blood was collected from naturally
iron - sufficient ( IS ; n = 10 ) and
iron - deficient ( ID ; n = 10 ) male and female infant
rhesus monkeys (
Macaca mulatta ) at 6 mo of age . -
pubmed
RESULTS : A total of 413 metabolites were measured , with differences in 40 metabolites identified between
IS and
ID monkeys at 6 mo ( P$\le $ 0.05 ) . -
pubmed
A phylogeny based on 37 single - copy genes of the main linear chromosome and rooted with the relapsing
fever species
Borrelia duttonii strain Ly revealed that
strain CA690 T had a sister - group relationship with , and occupied a basal position to , species occurring in North America . -
pubmed
BACKGROUND : Primary neuronal cultures are widely used to elucidate fundamental aspects of neuronal anatomy , physiology , cell biology , and
neuronal dysfunction in
animal models of disease . -
pubmed
PURPOSE : To assess the impact of laparoscopic extraperitoneal paraaortic staging in therapeutic planning and prognosis of
patients with locally advanced
cervical cancer ( LACC ) as compared with imaging staging . -
pubmed
Hydrocephalus has been reported in
patients with
Krabbe disease ; however , it is clinically difficult to monitor for
hydrocephalus in
patients with
Krabbe disease as symptoms of increased intracranial pressure may overlap with symptoms of
Krabbe disease . -
pubmed
We describe a case series of spontaneous third ventriculostomy and
hydrocephalus , likely in response to increased intracranial pressure , in
patients with infantile
Krabbe disease . -
pubmed
METHODS : Brain magnetic resonance images of
patients with infantile
Krabbe disease were retrospectively analyzed to assess for ventricular size and presence of spontaneous third ventriculostomies . -
pubmed
RESULTS : Seventy - five
patients with infantile
Krabbe disease were evaluated . -
pubmed
CONCLUSIONS : Spontaneous third ventriculostomies , likely in the context of increased intracranial pressure , were identified in
patients with
Krabbe disease . -
pubmed
Although difficult to assess , our study highlights the importance of monitoring for increased intracranial pressure , which can result in spontaneous third ventriculostomies , in
patients with infantile
Krabbe disease . -
pubmed
Perioperative
myocardial injury risk after elective knee and hip arthroplasty in
patients with a high risk of
obstructive sleep apnea . -
pubmed
BACKGROUND :
Myocardial injury after non - cardiac surgery ( MINS ) occurs in approximately 8 - 13 % of
patients and has significant 30 - day mortality . -
pubmed
Patients with
obstructive sleep apnea (
OSA ) suffer recurrent
hypoxemia during sleep and surgical
patients with
OSA are known to have increased risk of cardiorespiratory complications . -
pubmed
We hypothesized that
patients at high risk for
OSA may have an increased risk of
MINS . -
pubmed
CONCLUSION : The incidence of
MINS and postoperative cardiopulmonary complications in
patients with elective arthroplasty and a high risk of
OSA were low . -
pubmed
The assessment of pancreatic exocrine function in
patients with inoperable
pancreatic cancer : In need of a new gold - standard . -
pubmed
BACKGROUND :
Pancreatic exocrine insufficiency is commonplace in
patients with
pancreatic cancer , adversely impacting on quality of life and survival . -
pubmed
Nevertheless , a lack of consensus remains about the optimal diagnostic method , specifically in
patients with
pancreatic cancer . -
pubmed
CONCLUSION : Further research is required to identify the most optimal and accurate diagnostic tool to diagnose
pancreatic exocrine insufficiency in
patients with
pancreatic cancer in clinical practice . -
pubmed
Clinical Outcome of
Edoxaban vs.
Vitamin K Antagonists in
Patients with
Atrial Fibrillation and
Diabetes Mellitus : Results from a Multicenter , Propensity - Matched , Real - World Cohort Study . -
pubmed
Diabetes mellitus (
DM ) is a
chronic metabolic disease which is independently associated with unfavorable clinical outcomes in
patients with
atrial fibrillation (
AF ) . -
pubmed
Few real - world data are available about the clinical performance of non - vitamin K oral anticoagulants ( NOACs ) among
patients with
atrial fibrillation and
diabetes . -
pubmed
In this study , we considered
patients with
AF and
diabetes on
Edoxaban or VKAs therapy included in the multicenter
Atrial Fibrillation Research Database ( NCT03760874 ) . -
pubmed
We identified 557
AF patients with
diabetes who received
Edoxaban ( n : 230 ) or VKAs ( n : 327 ) treatment . -
pubmed
Conclusions : Our data support the hypothesis of the safety and efficacy of
Edoxaban for use in
patients with
AF and
diabetes , justified by a favorable NCB over VKAs . -
pubmed
METHODS : In a series of autopsy - confirmed cases of
CBD , we identified
patients with cognitive rather than motor predominant features ( CBD - Cog ) , including 5
patients thought to have
Alzheimer disease (
AD ) and 10
patients thought to have
behavioral variant frontotemporal dementia (
FTD ) . -
pubmed
We compared clinical and pathologic features of
CBD - Cog with those from a series of 31
patients with
corticobasal syndrome (
CBD -
CBS ) . -
pubmed
CONCLUSION : A subset of
patients with
CBD has a cognitive predominant
syndrome than can be mistaken for
AD or
FTD . -
pubmed
RESULTS :
Children had dental
caries with mean def - t 6 year old 5.6 + -3.2 , 7 year old 11 + -5.9 , 8 year old 5.8 + -4.0 , 9 year old 3.8 + -1.7 , 10 year old 4.4 + -2.3 , 11 year old 2.5 + -0.7 dan 12 year old 3.0 + -2.7 The def - t was correlated with dietary habits and dental health status . -
pubmed
In total , 1,008
pigs ( ~44 kg
body weight [ BW ] ) housed in 48 pens by sex , 21
pigs per pen , were fed diets with one of three
rye ( var . -
pubmed
For the entire trial ( d 0 to 76 ) ,
pigs fed increasing hybrid
rye level substituting
wheat grain had decreased ( P < 0.050 ) average daily feed intake ( ADFI ; L 3.05 , M 2.98 , H 2.91 kg / d ) and average daily
weight gain ( ADG ; L 1.01 , M 1.00 , H 0.97 kg / d ) . -
pubmed
Prophylactic
abdominal aortic balloon occlusion ( PAABO ) is a novel and efficient therapy for these
patients . -
pubmed
METHODS : A total of 48
parturients with
PAS were enrolled and divided into two groups . -
pubmed
CONCLUSIONS :
PAABO reduced perioperative blood loss and the risk of hysterectomy among
parturients with
PAS . -
pubmed
This study aimed to investigate the molecular and clinical characteristics in Thai
patients with
ACHM . -
pubmed
METHODS : Seven unrelated Thai
patients with
ACHM were recruited . -
pubmed
In the blood serum of
rabbits receiving an atherogenic diet , the content of cardiolipin involved in the immune mechanisms of
atherosclerosis development and a risk factor for
thrombosis , sharply increased . -
pubmed
Preexisting immunity shapes distinct antibody landscapes after
influenza virus infection and vaccination in
humans . -
pubmed
We sought to investigate the impact of preexisting immunity on generation of protective antibody responses to conserved viral epitopes upon
influenza virus infection and vaccination in
humans . -
pubmed
Prophylactic effect of rectal
indomethacin plus
nitroglycerin administration for preventing
pancreatitis after endoscopic retrograde cholangiopancreatography in female
patients . -
pubmed
In order to contain
infection of this highly contagious disease , most of the world population is constrained to live in a complete or partial lockdown for months together with a minimal
human - to -
human interaction having far reaching consequences on countries ' economy and mental well - being of their citizens . -
pubmed
Acute Dose - Dependent Neuroprotective Effects of
Poly ( pro-17beta - estradiol ) in a
Mouse Model of
Spinal Contusion Injury . -
pubmed
Following contusive
spinal cord injury in adult
male mice ,
poly ( pro - E2 ) films were implanted subdurally and neuroprotection was assessed using immunohistochemistry 7 days after
injury and implantation . -
pubmed
Left ventriculography with selective coronary angiography was performed on 13
patients with acute
myocardial infarcts complicated by
cardiogenic shock of
left ventricular failure and
hypotension . -
pubmed
Irreversible
ventricular fibrillation resulting in death occurred in one
patient 7 - 7 % ) during the opacification of the left coronary artery . -
pubmed
Intracellular accumulation of free
calcium in
mouse tumor cells exposed to anticancer drugs . -
pubmed
Alterations in concentrations of intracellular free
calcium ( [
Ca2+]i ) were examined in
mouse sarcoma S-180 cells exposed to
cisplatin ,
mitomycin C and
adriamycin , as related to cell viability . -
pubmed
When transgenic
mice that do not display the MEN 2 phenotype are crossed to a different background , the progeny display the
MEN 2 phenotype . -
pubmed
This observation bears special relevance to the
human syndrome in that this model system may be used to study the question of penetrance of phenotype . -
pubmed
Antibody - dependent enhancement ( ADE ) of
hantavirus infections ( strains
Hantaan 76 - 118 and SR-11 ) was studied using
macrophage - like cell lines (
J774.1 ,
P388D1 , and
U937 ) . -
pubmed
These data may be of use as more
patients are being considered for recently advocated surgical treatments for impending and established
macular hole . -
pubmed
To assess differences in hospital course and outcome , the authors studied 8 survivors of
sudden death syndrome and 17
patients with preoperative
ventricular tachycardia refractory to conventional antiarrhythmic therapy who underwent coronary revascularization and prophylactic implantation of an ICD system in either one or two stages . -
pubmed
Patients with advanced
coronary disease ,
poor ventricular function , and silent
ischemia received the ICD system in one stage . -
pubmed
It was concluded that the prophylactic use of the ICD system is an important adjuvant in the treatment of postoperative
malignant arrhythmias for
patients undergoing myocardial revascularization . -
pubmed
We report on a total of 45 of our most recent
patients who underwent penile prosthesis implantation for
erectile dysfunction . -
pubmed
With recent advances in diagnostic techniques associated with equine
lameness , there is a tendency to reduce our reliance on the most important part of purchase evaluation of the
horse - the hands - on physical examination . -
pubmed
Susceptibility of N'Dama and Boran cattle to tsetse - transmitted primary and rechallenge
infections with a homologous serodeme of
Trypanosoma congolense . -
pubmed
Eight trypanotolerant N'Dama cattle controlled an
infection of
Trypanosoma congolense ILNat 3.1 transmitted by
Glossina morsitans centralis , more efficiently than a group of similarly infected trypanosusceptible Boran cattle . -
pubmed
Thus , the trypanotolerant N'Damas controlled a primary
infection of
T. - pubmed
congolense more efficiently than trypanosusceptible
Boran cattle and eliminated a homologous rechallenge
infection without the pathology associated with the disease . -
pubmed
A double - blind , randomized , cross - over study was carried out on the effect of a sedative and a non - sedative antihistamine on 25
adults with
atopic dermatitis . -
pubmed
Inherited
human prion diseases . -
pubmed
Preliminary results of biological tests of the products showed that
8 ( 2 ) , 8 ( 2 )- difluoroprotoporphyrin accumulates to
gastric cancer more selectively than other
fluorine analogues and that
3 ( 2 ) , 3 ( 2 ) , 8 ( 2 ) , 8 ( 2 )- tetrafluoroprotoporphyrin is taken up by
rat hepatoma cells more readily than the others . -
pubmed
Metabolic activity of microcarrier attached liver cells after intraperitoneal transplantation during severe
liver insufficiency in the
rat . -
pubmed
Intraperitoneal transplantation of
MAL immediately after subtotal hepatectomy resulted in a significantly lower plasma
ammonia level , a higher
caffeine clearance , a higher
urea production and a significantly smaller loss in
body weight in comparison to sham transplanted control
rats . -
pubmed
Care for the
child with
central nervous system tumors . -
pubmed
The anaesthetic management of two
patients with severe
muscle weakness -- one suffering from acute
dermatomyositis , the other from acute
polymyositis -- is described . -
pubmed
Both
patients presented for surgery for
malignancy . -
pubmed
Ouabain inhibits intracellular pH recovery from
acidosis in cultured
mouse heart cells . -
pubmed
The spectrum of renal histopathology in
patients with significant
proteinuria in Vanuatu . -
pubmed
Three of the 21 patients had evidence of active
malaria at the time of presentation , and all of these patients had
Plasmodium falciparum . -
pubmed
Hematuria in
patients with
malrotated kidneys . -
pubmed
Persistent microscopic
hematuria and
proteinuria were found in 3
patients with
malrotation of the kidneys . -
pubmed
This technique definitely adds important clinical information and helps to determine the initial investigations in these
patients with
congenital anomalies of the kidney complicated by persistent
hematuria . -
pubmed
Polyacrylamide gel electrophoresis of
Loxosceles reclusa venom demonstrated that only one of seven or eight major ( plus three or four minor ) protein components caused
necrosis in
guinea pig skin . -
pubmed
Recognition of syntactic structure in
aphasic patients . -
pubmed
Accumulation of
dopamine by blood platelets from normal subjects and
parkinsonian patients under treatment with
L - DOPA . -
pubmed
Platelets from
parkinsonian subjects receiving oral
L - DOPA also took up
dopamine.3 . -
pubmed
In two out of three samples of platelets from
parkinsonian subjects , traces of a
dopamine - like substance were detected , but this finding requires confirmation.6 . -
pubmed
[ Clinical and secondary clinical chemical studies in
patients with biliary operations and histologically proven
liver damage ] . -
pubmed
[ The erythrocyte picture in
chronic lung diseases of the
horse ] . -
pubmed
In the present study , we examined the mechanisms of
naloxone 's actions in conscious
rabbits made
hypotensive by
hemorrhage . -
pubmed
Naloxone treatment in
hypotensive -
hypovolemic , conscious
rabbits results in an increase in mean arterial blood pressure ( BP ) and a decrease in heart rate ( HR ) . -
pubmed
The risks which result from hemodynamic changes after surgery of 35
patients with supratentorial
arterio - venous angiomas were investigated . -
pubmed
[ Status and treatment of the upper respiratory tract in
patients with
acute pneumonia ] . -
pubmed
Seventeen
children with severe
asthma received active
salbutamol ( 4 mg via a nebuliser , 400 micrograms as an inhalational powder , or a 4 mg tablet ) together with complementary placebos on a double - blind , triple - dummy randomly allocated basis . -
pubmed
Immunogenetic analysis of
patients with
post - schistosomal liver cirrhosis in
man . -
pubmed
Immune responsiveness of 121
patients with
post - schistosomal liver cirrhosis to schistosomal antigens was investigated . -
pubmed
The frequency of low responders to schistosomal adult worm antigen was significantly decreased in the
patients with
post - schistosomal liver cirrhosis ( P less than 0.05 ) . -
pubmed
These observations suggested that an HLA - linked immune suppression gene controlled susceptibility or resistance to
post - schistosomal liver cirrhosis through regulation of immune responsiveness of the hosts to schistosomal
antigen in
man . -
pubmed
Intact
mice demonstrated a dramatic
hyperglycemia at 1 h after endotoxin treatment , a response absent in adrenalectomized
mice . -
pubmed
Plasma
glucose levels were significantly reduced from control values at 3 and 6 h posttreatment , with the most pronounced endotoxin - induced
hypoglycemia seen in adrenalectomized
mice . -
pubmed
The efficacy of
N - acetylcysteine in preventing
doxorubicin - induced
cardiomyopathy in
dogs . -
pubmed
Some ultrastructural aspects of
human pathological pelvi - ureteric junction in
idiopathic hydronephrosis . -
pubmed
Hepatic arteriography in
patients with
hepatocellular carcinoma : change in findings caused by balloon occlusion of
tumor - draining hepatic veins . -
pubmed
Accordingly , we studied the change in blood flow visible on hepatic arteriograms when a segment of the hepatic vein is temporarily occluded in
patients with
hepatocellular carcinoma . -
pubmed
MATERIALS AND METHODS : The study group consisted of 24
patients with
nodular - type hepatocellular carcinoma . -
pubmed
RESULTS : Conventional hepatic arteriography showed the
tumor - draining veins to be branches of the portal vein in only two of the 24
patients ( 8 % ) . -
pubmed
Hepatic arteriography during
venous occlusion , however , showed the
tumor - draining veins to be branches of the portal vein in four of the
patients ( 17 % ) . -
pubmed
An increase in the degree of
tumor vascularity with
venous occlusion was observed only in a
patient with an initial arteriohepatic vein shunt . -
pubmed
Dense hepatogram and hepatofugal opacification of the portal vein branches in the occluded ,
tumor - bearing segment were obtained in 10
patients ( 42 % ) . -
pubmed
Eight of these did not have
liver cirrhosis , whereas all of the remaining 14
patients did ( p & lt ; .001 ) . -
pubmed
A relationship to the undifferentiated primitive
neuroectodermal tumours of the central nervous system in
children was assumed by the title of these
tumours , although it was recognised that they were not necessarily related to peripheral nerves . -
pubmed
Identification and characterization of immunodominant antigens during the course of
infection with
Brucella ovis . -
pubmed
OBJECTIVE : This paper compares the effects of
goat 's milk and
cow 's milk on
weight gain and fat absorption , in children with overt
malnutrition . -
pubmed
One
death with
candidiasis occurred in the
goat 's milk group . -
pubmed
Strength in bending was determined for interdental fixation apparatuses applied to hemimandibles obtained from 24
canine cadavers . -
pubmed
Hemolytic - uremic syndrome in a six - year - old girl after a
urinary tract infection with Shiga - toxin - producing
Escherichia coli O103 : H2 . -
pubmed
Comparison of the small 16S to 23S intergenic spacer region ( ISR ) of the rRNA operons of some
Escherichia coli strains of the ECOR collection and
E. - pubmed
Several 16S to 23S spacers of 354 bp have been sequenced from six
Escherichia coli strains belonging to the ECOR collection . -
pubmed
We have already demonstrated that the final height in
GH - deficient children with spontaneous puberty with gonadal suppression therapy by
medroxyprogesterone or
cyproterone acetate was significantly taller than
GHD with spontaneous puberty without gonadal suppression therapy . -
pubmed
With a more conservation definition of the
syndrome , employing a primary cohort of
patients with
PTSD of one year or greater duration ,
brofaromine significantly reduced
PTSD symptoms in comparison with placebo . -
pubmed
Further study may ultimately define a role for the use of
sodium polystyrene sulfonate in the treatment of
patients with
chronic lithium toxicity . -
pubmed
Nineteen
patients with
RAU ( 12 minor type and 7 major type ) and 8 healthy volunteers , of both sexes , aged 24 - 54 years old were tested . -
pubmed
The standard is designed to eliminate or minimize occupational exposure to
Hepatitis B Virus (
HBV ) ,
Human Immunodeficiency Virus (
HIV ) and other bloodborne pathogens . -
pubmed
[
Hepatitis B virus reactivation after allogeneic bone marrow transplantation in a patient previously cured of
hepatitis B ] . -
pubmed
We report a case in a
patient with natural immunity to
hepatitis B who had undergone allogenic bone marrow transplantation with an identical sibling donor one year before for the
chronic myelogenous leukemia in the first chronic phase . -
pubmed
The clinical effect of
faropenem was evaluated in 165 ambulatory
patients with various
infections in the field of obstetrics and gynecology at 10 institutions in Yamagata Prefecture . -
pubmed
The significance of the time course of ST segment elevation just after reperfusion therapy for
acute myocardial infarction was investigated in 25 consecutive
patients with acute
myocardial infarction and ST elevation . -
pubmed
To examine auto - antibody production in
periodontitis patients , Western immunoblotting with
human gingival fibroblasts was performed . -
pubmed
Immuno - reactivity against
human gingival fibroblasts was examined with sera from 30
periodontitis patients and 10 periodontally healthy subjects . -
pubmed
In this study we present an analysis of 11
patients presenting
congenital bilateral absence of the vas deferens (
CBAVD ) . -
pubmed
METHODS : Serum
TTV - DNA was studied in spouses of 41 subjects with
TT viremia . -
pubmed
New information promises to clarify some of the complex issues of the physiological roles of
estrogen and the contribution of
estrogen to the development of
neoplastic diseases in
humans . -
pubmed
The influence of age at exposure to radiation on
cancer risk in
humans . -
pubmed
Human histologic evaluation of a bone graft combined with GTR in the treatment of
osseous dehiscence defects : a case report . -
pubmed
SUBJECTS & amp ; METHODS : The subjects were five
patients with
IBM confirmed pathologically . -
pubmed
The purpose of the present study was to elucidate the relative effectiveness of several PMN agonists in stimulating lysosomal - enzyme secretion and
leukotriene ( LT ) B ( 4 ) production by PMNs isolated from
diabetic subjects . -
pubmed
It is surprising that PMNs from these same
diabetic subjects responded normally after stimulation with
A23187 , serum - opsonized zymosan , or
phorbol myristate acetate . -
pubmed
RESULTS :
Restenosis was found in 23 ( 24 % )
patients within the first 6 months . -
pubmed
Multivariate analysis revealed a significantly reduced risk for
restenosis in these
patients compared to
patients without the short allele ( odds ratio 0.2 , 95 % Cl 0.06 to 0.70 , p = 0.007 ) . -
pubmed
[ Assessment of long - term bone metabolism in
patients with relative
hypoparathyroidism after changing the
calcium concentration of the dialyzate to 3mEq / L ] . -
pubmed
Factors involved include the increasing number of older and
diabetic patients initiating dialysis . -
pubmed
In conclusion , the use of a 3 mEq / l dialysate
calcium may improve
hypoparathyroidism in a substantial number of
patients , avoiding the untoward effect that lower
calcium concentration has on bone mineralization . -
pubmed
We studied the
hypercholesterolemic rabbit model in order to evaluate potentials of regression of
arteriosclerosis by measuring various blood and plaque parameters . -
pubmed
We tested the hypothesis that two glasses of red wine , taken together with the noon meal , would cause postprandial reduction in blood pressure in
hypertensive individuals . -
pubmed
Eighty - eight
thyrotoxic lactating
mothers and their
infants were studied . -
pubmed
Serum
MMI was measured in the
infants of
thyrotoxic mothers taking 20 - 30 mg
MMI . -
pubmed
Mean+/-SD of free T4 index ( FT4I ) in
thyrotoxic mothers treated with 20 and 30 mg
MMI for one month decreased from 20.1+/-4.2 to 9.7+/-1.5 ( p<0.001 ) and from 20.6+/-4.8 to 8.6+/-3.0 ( p<0.001 ) , respectively . -
pubmed
The dose of
MMI was adjusted and thyroid function remained normal up to 12 months of
MMI therapy in
thyrotoxic lactating
mothers . -
pubmed
Bisphenol A (
BPA ) , an environmental
estrogen derived from the plastic industry , was given orally via incorporation into the food of 30 male and female
polecats at 3 different doses ( 10 , 50 , or 250 mg / kg
body weight / day ) for 2 wk with 10
animals acting as controls . -
pubmed
We report the case of a 31 - year - old
woman who delivered twins by Caesarean section in whom atonic
uterine haemorrhage developed 6 h postoperatively . -
pubmed
During conservative treatment with the high - dose
prostaglandin analogs
sulprostone (
PGE ( 2 ) ) and
dinoprost (
PGF ( 2alpha ) ) , acute
pulmonary oedema and
cardiac decompensation developed and , subsequently , the
patient suffered
cardiopulmonary arrest . -
pubmed
Despite 2h of CPR , the
patient was discharged from hospital 3 months later without any major physical or
neurocognitive deficit . -
pubmed
METHODS : Clinical data of 37
PBC patients together with pathological findings of 20
PBC patients were reviewed . -
pubmed
Liver biopsy in 20
PBC patients mainly found :
fibrosis in 17 cases ( 85 % ) ,
interlobular bile duct lesions in 13 ( 65 % ) ,
lobular mononuclear inflammation in 13 ( 65 % ) ,
lymphocytic hepatocellular piecemeal necrosis in 10 ( 50 % ) , and bile pigment accumulation in 9 ( 45 % ) . -
pubmed
CONCLUSIONS :
PBC is mostly found in middle - aged
women . -
pubmed
The impact of parasitism by
Asobara tabida on
Drosophila melanogaster larval development , survival features and larval activity has been investigated using two
strains of the parasitoid . -
pubmed
ZOSTER
MENINGOENCEPHALITIS IN A
STEROID - TREATED
PATIENT . -
pubmed
Breast carcinoma is the most common
carcinoma in women in Europe and its early diagnosis and treatment is important for the overall survival of the
patients . -
pubmed
Mitral regurgitation in
patients with advanced
systolic heart failure . -
pubmed
BACKGROUND :
Mitral regurgitation (
MR ) may develop in
patients with advanced systolic
congestive heart failure (
CHF ) without organic
mitral valve disease and contribute to worsening symptoms and survival . -
pubmed
Surgical mitral annuloplasty improves symptoms in
patients with advanced
CHF , and percutaneous approaches to mitral annuloplasty are being developed . -
pubmed
Our objective was to define the prevalence , clinical correlates , and prognostic implications of functional MR and the use of mitral annuloplasty in
patients with advanced systolic
CHF evaluated in a
heart failure clinic . -
pubmed
Of 716
patients with advanced
CHF , 558 had satisfactory baseline echocardiograms performed at our institution . -
pubmed
The severity of
MR was confirmed by quantitative analysis in 72 % of
patients with hemodynamically significant
MR ( more than moderate ) . -
pubmed
Patients with hemodynamically significant
MR had higher mortality ( P=.03 ) but not when controlling for age , sex , cause , New York Heart Association class , and ejection fraction ( P=.95 ) . -
pubmed
CONCLUSION : Among
patients with advanced
CHF , hemodynamically significant
MR is common . -
pubmed
A
feline lymphoblastoid cell line (
KO-1 ) was established from a 5 - year - old neutered female
cat with naturally occurring
thymic lymphoma . -
pubmed
MATERIALS AND METHODS : From 1980 to 2003 we identified 5
patients with
urinary matrix stones referred to our tertiary medical center for evaluation and treatment . -
pubmed
Scientifically based training methods are now being applied in rehabilitation of
patients after
stroke and
trauma , and in the sensory retraining techniques currently applied in the treatment of
focal hand dystonia as well as in sensory re - education after nerve repair in hand surgery . -
pubmed
Increased carrageenan - induced
acute lung inflammation in old
rats . -
pubmed
Consistent with the biochemical markers of
inflammation , increased
lung damage , as assessed by nitrosative stress and lipid peroxidation , was observed in carrageenan - treated old
rats . -
pubmed
Therefore , the use of
Vitex doniana to control
postpartum bleeding after child birth may be justified . -
pubmed
Mesalazine and/or
Lactobacillus casei in preventing
recurrence of symptomatic uncomplicated
diverticular disease of the colon : a prospective , randomized , open - label study . -
pubmed
GOALS : To investigate the effectiveness and safety of
mesalazine , with or without
Lactobacillus casei , in preventing
recurrence of symptomatic
diverticular disease of the colon . -
pubmed
Ninety consecutive
patients ( 36
men , 54
women , mean age 67.5 y , range 39 to 84 y ) , previously affected by symptomatic uncomplicated
diverticular disease of the colon ( remission obtained with
rifaximin 800 mg / d plus
mesalazine 2.4 g / d for 10 d , followed by
mesalazine 1.6 g / d for 8 wk ) , were enrolled in a 12 - month follow - up . -
pubmed
RESULTS : Eighty - five
patients completed the study ( 94.5 % ): 2
patients ( 2.22 % , 1 of group M and 1 of group LM ) were withdrawn from the study for protocol violation and 1 ( 1.11 % ) for hospital admission due to
acute pulmonary disease ( group L ) ; 2
patients ( 2.22 % ) were lost to follow - up . -
pubmed
Only 10
patients ( 11.1 % ) showed
recurrence of symptoms ( overall symptomatic score : 68 ) . -
pubmed
Transplantation of fetal dopaminergic ( DA ) neurons can produce symptomatic relief for
patients with
Parkinson ' s disease , but the technical and ethical difficulties have limited the application of this therapy . -
pubmed
Monkey ESCs give rise to midbrain DA neurons , and the transplanted ESC - derived neurospheres function as DA neurons , attenuating the neurological symptoms of the
monkey Parkinson ' s disease model . -
pubmed
Between 1995 and 2001 , 17
patients received IORT for
soft tissue sarcomas of the extremities . -
pubmed
Two
patients experienced locoregional
relapses , six
patients recurred at metastatic sites , and one
patient died without
recurrence . -
pubmed
For
patients with
soft tissue sarcomas of the extremities , IORT used as a boost to EBRT provides excellent local control , with limited acute toxicities . -
pubmed
METHODS : We studied 13
patients ( mean age + /- 1 SD , 57 + /- 11 years ) with
pulmonary carcinoid tumours . -
pubmed
All
patients demonstrated a single
pulmonary lesion . -
pubmed
None of the
patients had recurrent
carcinoid disease or died during follow - up ( 864 + /- 218 days ) . -
pubmed
Mediastinal lymph node
metastases or extrathoracic
metastases were not detected in any
patient . -
pubmed
CONCLUSIONS : Clear lens extraction was an effective and predictable surgery to reduce
myopias and an apparently safe procedure in
patients with and without prophylactic preequatorial retinal photocoagulation . -
pubmed
METHODS : Eligible
patients were identified from the Dutch
AIDS Therapy Evaluation , The Netherlands ( ATHENA ) national observational cohort . -
pubmed
Patients can experience
ARVS , the risk for development of resistance after treatment interruption is realistic , and there is a potential hazard of
HIV transmission to sexual partners . -
pubmed
The procedure involves several rounds of the following three steps , starting from an allogeneic
human ES cell line : the creation of
tetraploid ES cells by fusion of somatic cells from the prospective PS with the ES cells , the differentiation of these cells into
tetraploid oogonia that give rise to diploid oocytes following meiosis , and the isolation of ES cells from parthenogenetic blastocysts , morula , 8 - cell embryos , or 4 - cell embryos derived from these oocytes . -
pubmed
The
rSVV established latent
infection in neural ganglia . -
pubmed
A subsequent study will evaluate the ability of rSVV vaccines expressing
SIV antigens to protect
nonhuman primates against simian
AIDS . -
pubmed
This chapter also illustrates the methods that can be used to test
hypoxia - inducible gene expression in vitro and in vivo , including
hypoxia treatment of cultured cells , generation of
murine ischemic heart models , and analysis of gene expression . -
pubmed
OBJECTIVE : This study was undertaken to analyze the outcome of
children with
DKA treated with a modified protocol at a tertiary level teaching hospital PICU in Pune , Maharashatra . -
pubmed
METHODS : We retrospectively analyzed case records of 12
patients ( 8
males and 4 females ) with
DKA ( 11 new and 1 readmission ) admitted in our PICU from January 2005 to June 2006 . -
pubmed
Acute
aldosterone infusion enhances
thrombosis development in normotensive
rats . -
pubmed
Role of distinct immune components in the radiation - induced abrogation of
systemic lupus erythematosus development in
mice . -
pubmed
The New Zealand Black x New Zealand White F1 [ ( NZB / NZW ) F1 ]
mouse develops an autoimmune condition resembling aspects of
human systemic lupus erythematosus (
SLE ) . -
pubmed
Kidney lesions were milder and autoantibody levels were lower in irradiated
mice . -
pubmed
Thus , a role for B-1 cells in
murine SLE can not be excluded , since the irradiation protocol did not effectively eliminate these cells . -
pubmed
Previous studies have demonstrated that Madin - Darby
canine kidney ( MDCK ) epithelial cells form
cysts when grown in a three - dimensional ( 3D ) extracellullar matrix ( ECM ) environment . -
pubmed
Applying strict clinical - laboratory criteria , 6
patients were diagnosed clinically with
PTMA and treated with plasma exchange . -
pubmed
Clinical variables , including underlying disease , conditioning regimen , stem cell donor status , duration and serum level of
cyclosporine ,
infections , and
acute graft versus host disease were compared statistically in
patients with histologic signs of
PTMA ( n=8 ) with those without PTMA ( n=12 ) . -
pubmed
RESULTS : PTMA was verified histologically in all 6
patients with a clinical diagnosis of
PTMA but only 2 of the 14
patients who were not clinically diagnosed had histologic evidence of
PTMA ( P<0.0001 ) . -
pubmed
RESULTS : After the first interim evaluation of 101
patients , the study was stopped because of a significant increase in temporary ipsilateral
vocal cord motility dysfunction in the retrojugular access group ( 31 % vs. 6 % , p=0.0014 ) . -
pubmed
No other significant differences concerning major complications (
death or
stroke ) , other
cranial nerve injuries ,
wound healing , or
patient satisfaction was observed neither in the early postoperative phase nor at follow up . -
pubmed
CONCLUSION : Due to the high incidence of temporary ipsilateral
vocal cord dysfunction in
patients undergoing retrojugular exposure of the carotid artery , we recommend the conventional ventrojugular approach , which can be performed by incision along the anterior border of the sternomastoid muscle or by transversal skin incision . -
pubmed
The present study aimed to clarify the order of changes in IMCL levels and skeletal muscle mitochondrial function during the development of
type 2 diabetes in Zucker diabetic fatty ( ZDF )
rats . -
pubmed
Fa / fa ZDF
rats were studied at 3 different ages corresponding to different stages of
type 2 diabetes , whereas fa/+
rats served as controls . -
pubmed
In vivo muscle oxidative capacity was not different in fa / fa
animals compared to controls , and in vitro enzyme activity data suggested improved functionality of enzymes involved in fat oxidation in
type 2 diabetic animals . -
pubmed
Accordingly , we can conclude that in the ZDF
rat model ,
type 2 diabetes develops in the absence of skeletal muscle
mitochondrial dysfunction . -
pubmed
We describe a 50 - year - old
woman with recurrent
neurologic deficits . -
pubmed
METHODS : Bile was aspirated during endoscopic retrograde cholangiopancreatography in consecutive
patients with
MBO . -
pubmed
RESULTS : Among 60
patients with
MBO , 16 ( 26.7 % ) had white bile . -
pubmed
A few weeks earlier the
man underwent an elective operation for an upper quadrant
tumor in the right lung . -
pubmed
DATA SOURCES : Searches were conducted to identify all published randomized , placebo - controlled , double - blind clinical trials available for review by May 2007 on the efficacy of continuation or maintenance treatment of major
depressive disorder with either
selective serotonin reuptake inhibitors ( SSRIs ) or tricyclic antidepressants ( TCAs ) that included
patients entering a maintenance phase after achieving remission from the acute phase . -
pubmed
METHODS : A retrospective study of consecutive
patients with
systemic sclerosis and
fecal incontinence was performed . -
pubmed
Results of the antimycobacterial assays indicated that the minimal inhibitory concentrations ( MICs ) and minimal bactericidal concentrations ranged from 1.22 microg / mL to 39.06 microg / mL for
Mycobacterium smegmatis and all studied
Mycobacterium tuberculosis strains for the crude extract from
D. - pubmed
tuberculosis H37Rv
strain was observed at Day 18 for
D. - pubmed
Results of the antigonorrhoeal assay indicated that
diospyrone was able to prevent the growth of all studied
strains of
Neisseria gonorrhoeae . -
pubmed
Major
postoperative complications occurred in 23 ( 26 % )
patients , including nine ( 10 % )
patients requiring reoperative treatment due to
skin flap necrosis ,
wound infection ,
hematoma , or
fascial dehiscence . -
pubmed
Fourteen
patients presented with
commotio retinae . -
pubmed
CONCLUSION :
Contusion may increase
ACD particularly in the peripheral region even in
patients who have no apparent manifestations in the anterior ocular segment . -
pubmed
In this communication we describe a young
woman who presented with a severe inflammatory illness that consequently developed into
pyoderma gangrenosum ,
anterior tibialis myositis and
arthritis that were all antecedent to the intestinal involvement . -
pubmed
Nonalcoholic steatohepatitis ,
animal models , and biomarkers : what is new ? -
pubmed
Nowadays , there are numerous
mice models to study
abnormal liver function such as
steatosis ,
NASH , and
hepatocellular carcinoma . -
pubmed
The study of the established
animal models has provided many clues in the pathogenesis of
steatosis and
steatohepatitis , although these remain incompletely understood and no
mice model completely fulfills the clinical features observed in
humans . -
pubmed
[ The clinical feature , diagnosis and management of
splenic artery aneurysms in liver transplant
patients ] . -
pubmed
CONCLUSIONS : Morbidity of
SAA is higher in
patients of
liver cirrhosis . -
pubmed
Extract from seeds and bark of
horse chestnut (
Aesculus hippocastanum L ) is used as an herbal medicine against
chronic venous insufficiency . -
pubmed
The aim of this study was to investigate the effects and mechanisms of action of
horse chestnut on the contraction of
bovine mesenteric veins and arteries , and
human platelet aggregation . -
pubmed
ADP - induced
human platelet aggregation was significantly reduced by
horse chestnut . -
pubmed
Human platelet aggregation is reduced by
horse chestnut . -
pubmed
OBJECTIVE : This study investigates the effectiveness of the Newborn Individualized Developmental Care and Assessment Program ( NIDCAP ) on neurobehavioral and electrophysiological functioning of preterm
infants with severe
intrauterine growth restriction (
IUGR ) . -
pubmed
STUDY DESIGN : Thirty
IUGR infants , 28 to 33 weeks gestational age , randomized to standard care ( control / C=18 ) , or NIDCAP ( experimental / E=12 ) , were assessed at 2 weeks corrected age ( 2wCA ) and 9 months corrected age ( 9mCA ) in regard to health , anthropometrics , and neurobehavior , and additionally at 2wCA in regard to electrophysiology ( EEG ) . -
pubmed
CONCLUSION : This is the first study to show NIDCAP effectiveness for
IUGR preterm
infants . -
pubmed
OBJECTIVE :
Mild cognitive impairment (
MCI ) is a
syndrome thought to be a prodrome of
dementia for some
patients . -
pubmed
One subtype ,
amnestic MCI (
aMCI ) , may be specifically predispose
patients to develop
Alzheimer ' s dementia (
AD ) . -
pubmed
METHODS : One thousand seven hundred seventy - nine
participants in the National Alzheimer 's Coordinating Center ( NACC ) with
MCI were included in this study . -
pubmed
All
participants were evaluated systematically with a thorough cognitive battery , clinical interview , and consensus diagnoses , and subtyped as : ( 1 ) amnestic (
aMCI ) ( single- or multiple - domain ) versus non - amnestic ( non - aMCI ) ; ( 2 )
executive dysfunction -
MCI (
exMCI ) ( single- or multiple - domain ) versus no
executive dysfunction -
MCI ( non - exMCI ) ; ( 3 ) both
aMCI and
exMCI ; and ( 4 ) neither
aMCI nor
exMCI . -
pubmed
BACKGROUND : Although numerous biomarkers may be prognostically meaningful in
patients with acute
dyspnea , few comparative analyses have addressed possible associations between a wide range of candidate biomarkers and clinical variables . -
pubmed
A final risk model was derived , and this model was then validated by applying it to patients from a separate cohort of acutely
dyspneic patients . -
pubmed
Comparative evaluation of
chemotoxicity and
phototoxicity using
Mel - HEV and
CPZ ( as positive control ) was performed on
mouse fibroblast cell line '
Balb / c 3T3 ' . -
pubmed
Low - dose
methotrexate and
azathioprine are the most useful immunosuppressive drugs and are indicated in
patients with of failure or contra - indication of
corticosteroids or in those
patients who needs a long term
prednisone dose higher than 10 mg daily to control the
sarcoidosis . -
pubmed
Infliximab can be useful in some severe
sarcoidosis patients refractory to classical treatment , except for
cardiac involvement . -
pubmed
Time delay between symptom and surgery in
patients with
carotid artery stenosis . -
pubmed
A total of 142 carotids in 139
patients with symptomatic
stenoses between 2002 and 2006 were included . -
pubmed
There are several measures to improve the chain of procedures for
patients with
carotid artery stenosis . -
pubmed
The criteria address structural , process and
human resource requirements and medical aspects for the accreditation of various level of
trauma centre . -
pubmed
CONCLUSION : There is a great opportunity to apply best practice criteria to improve the care of
trauma in South Africa and improve
patient outcome . -
pubmed
Porcine teschovirus polioencephalomyelitis in western Canada . -
pubmed
Beginning in 2002 , a small number of
pig farms in western Canada began reporting 4 - 7 - week - old
pigs with bilateral hind - end
paresis or
paralysis . -
pubmed
Low numbers of
pigs were affected , some died , most had to be euthanized , and those that survived had reduced
weight gains and
neurological deficits . -
pubmed
To the authors ' knowledge , this is the first report of
teschovirus encephalitis in western Canada and the first reported case of
polioencephalomyelitis in
pigs in Canada , where teschovirus was confirmed as the cause . -
pubmed
BACKGROUND / AIMS :
EBV has been associated with
Burkitt lymphoma (
BL ) . -
pubmed
It establishes a
latent infection but its reactivation has been observed in
patients receiving long - term chemotherapy . -
pubmed
Fermented
soybean liquid ( FSL ) has been well cited for its broad spectrum of biological effects , yet its documented
gastropeptic ulcer (
GPU ) ameliorating effect is still lacking . -
pubmed
METHODS : The authors analysed 70
patients with
PMR , 20 with
GCA , and 24 healthy controls ( HC ) . -
pubmed
CONCLUSION :
Myrsinane - type
diterpene Proliferin A from
Euphorbia prolifera shows
cytotoxic effect against
human ovarian cancer cell line
A2780 . -
pubmed
We describe the management of interrupted
aortic arch associated with
coronary artery disease through single - stage surgical procedure without cardiopulmonary bypass in a 56 - year - old
woman . -
pubmed
RESULTS : Ninety - two
patients survived from a total 163
patients with
VAP during the course of their confinement in the intensive care unit . -
pubmed
Multivariable logistic regression analysis identified that a pre - existing Charlson Comorbidity Index score ( P = .011 ) , initial oxygenation index ( P = .025 ) , SOFA score ( P = .043 ) ,
VAP caused by
Acinetobacter baumanii ( P = .030 ) , and
infection with MDR pathogens ( P = .003 ) were independent risk factors for hospital mortality in patients with
VAP . -
pubmed
CONCLUSION : High Charlson Comorbidity Index score , high initial oxygenation index , high SOFA score , and
infection with
Acinetobacter baumannii or MDR pathogens significantly affect hospital mortality in patients with
VAP . -
pubmed
A
CCl ( 4 )-induced
liver fibrosis model in
mice was also utilized . -
pubmed
The authors report the rare case of a 58 - year - old
man with segmental arterial mediolysis (
SAM ) with associated
intracranial and intraabdominal aneurysms , who suffered
subarachnoid hemorrhage (
SAH ) due to
rupture of an
intracranial aneurysm . -
pubmed
The
patient presented with severe
headache and
vomiting . -
pubmed
Ninety - six
patients ( 96/181 , 53.0 % ) were reported to have
thyroid disease . -
pubmed
Surgical management of
thyroid disease was performed in 80.2 % ( 77/96 ) of
patients with
thyroid disease , with total thyroidectomy being the most common operation reported ( 23/77 , 29.9 % ) . -
pubmed
CONCLUSION : Careful monitoring of
thyroid disease in
CS patients is imperative . -
pubmed
To investigate the anti - asthmatic effects of CF and their underlying mechanism , we examined the influence of CF on the development of
pulmonary eosinophilic inflammation and
airway hyperresponsiveness in a
mouse model of
allergic asthma . -
pubmed
Postnatal effects of prenatal
nicotine exposure on
body weight , brain size and cortical connectivity in
mice . -
pubmed
The current study uses a prenatal
nicotine mouse model to determine effects of PNE on
body weight , brain weight , brain length and development of neocortical circuitry , including thalamocortical afferents ( TCAs ) and intraneocortical connections ( INCs ) . -
pubmed
Interestingly , the reduction of
body weight , brain weight , and brain length observed in newborn PNE
mice compared to control
mice was no longer present at postnatal day ( P ) 10 . -
pubmed
The risk of
coughing increased with
tobacco smoking and the number of sticks smoked per day . -
pubmed
Campylobacter jejuni is the major worldwide cause of
bacterial gastroenteritis . -
pubmed
We studied the 2 - year outcome of deep - brain stimulation at the ventral anterior limb of the internal capsule and ventral striatum for 4
patients with treatment - resistant
OCD . -
pubmed
Alveolar echinococcosis is a
parasitic infectious disease caused by the larval stage of
Echinococcus multilocularis , which is one of the two most important species of Echinococcus . -
pubmed
Protective effects of Galla Rhois , the excrescence produced by the
sumac aphid ,
Schlechtendalia chinensis , on transient focal
cerebral ischemia in the
rat . -
pubmed
Oral administration of GRE ( 300 mg / kg ) in a transient focal
cerebral ischemia rat model ( two hours of occlusion followed by 22 hours of reperfusion ) reduced the
brain infarct volume by 37.5 % . -
pubmed
In conclusion , GRE had potent radical - scavenging activities and neuroprotective effects in a
rat model of
stroke when it was pre- and co - administered . -
pubmed
Biopsies of 7
patients with
LB were stained before and after
azithromycin treatment . -
pubmed
Seven of 8
patients with
leiomyosarcoma with follow - up had
recurrence within the follow - up period , whereas there were no
recurrences in patients with cellular
leiomyoma . -
pubmed
METHODS : The
menstrual bleeding pattern was registered in fertile
women undergoing open - heart surgery in 2010 - 12 . -
pubmed
Haematocrit and 24 - h postoperative
bleeding were compared with those of
men undergoing cardiac surgery . -
pubmed
Unplanned
menstrual bleeding ( lasting 2 - 5 days ) was detected in 13 ( 60 % )
patients . -
pubmed
Ten
women took
oral contraceptives , 8 of whom had unexpected
menstrual bleeding during admission . -
pubmed
Men ( n = 22 ) , with a mean age of 35 ( range 17 - 54 ) years , had mean
bleeding of 331 ( range 160 - 796 ) ml postoperatively , which was not statistically significantly different from the women 's . -
pubmed
Streptococcus tigurinus is highly virulent in a
rat model of experimental
endocarditis . -
pubmed
Streptococcus tigurinus is responsible for
systemic infections in
humans including
infective endocarditis . -
pubmed
tigurinus in
humans correlated with an increased ability to induce
IE in
rats . -
pubmed
tigurinus
strains AZ _ 3a(T ) , AZ_4a ,
AZ _ 8 and
AZ _ 14 , isolated from patients with
infective endocarditis or with the well known IE pathogen
Streptococcus gordonii ( Challis ) . -
pubmed
Aortic infection was assessed after 24 h.
S. - pubmed
tigurinus AZ_3a(T ) , AZ_4a and
AZ _ 14 produced
endocarditis in & gt;=80 % of
rats whereas
S. - pubmed
Multi - institutional validation of a preoperative scoring system which predicts survival for
patients with
glioblastoma . -
pubmed
Glioblastoma is the most common and aggressive type of primary
brain tumor in
adults . -
pubmed
Of the 334
patients in this study from three different institutions , the preoperative factors found to be negatively associated with survival in a Cox analysis were age & gt;60 years ( p<0.0001 ) , Karnofsky Performance Scale score & lt;=80 ( p=0.03 ) ,
motor deficit ( p=0.02 ) ,
language deficit ( p=0.04 ) , and
periventricular tumor location ( p=0.04 ) . -
pubmed
METHODS : We retrospectively reviewed HBUS reports in
traumatic brain injury (
TBI )
patients admitted to our tertiary neuro - critical care unit ( NCCU ; January 2005 - June 2011 ) . -
pubmed
We included
patients receiving an HBUS for isolated LFTs derangement , excluding pre - existing
hepato - biliary diseases or
trauma . -
pubmed
CONCLUSIONS : In
TBI patients , HBUS did not appear sensitive in detecting causes for isolated LFT abnormalities . -
pubmed
CASE PRESENTATION : A 63 - year - old Hispanic
man presented with
prostatism of several months ' evolution . -
pubmed
This is illustrated here through studies on PEMs as synthetic vaccine candidates targeting the
malaria parasite and the
human immunodeficiency virus type-1 (
HIV-1 ) . -
pubmed
METHODS AND RESULTS : We report the case of a 42 - year - old
female with
OOM caused by a
hemangiopericytoma of the left ethmoid
sinus . -
pubmed
Anisakis morphotype I is the principal etiologic agent of
human anisakiasis , with differences in pathogenicity found between the Anisakis simplex s.s . -
pubmed
( 93 and 91 % lower , respectively ) , they may still be implicated in
human anisakiasis , as they are capable of attaching to and penetrating the gastrointestinal wall of animals , demonstrating a similar pathogenicity to that of
A. - pubmed
The pathogenesis of
bleomycin - induced
lung injury in animals and its applicability to
human idiopathic pulmonary fibrosis . -
pubmed
Bleomycin , an anti - neoplastic agent that causes
lung fibrosis in
human patients has been used extensively in
rodent models to mimic
IPF . -
pubmed
In this review , we compare the pathogenesis and histological features of
human IPF and
bleomycin - induced
pulmonary fibrosis (
BPF ) induced in
rodents by intratracheal delivery . -
pubmed
SUBJECTS AND METHODS :
CAP was diagnosed in
patients ( 6
men aged 19 - 24 years and 1
woman aged 49 years ) on the basis of clinical , laboratory , and radiological findings . -
pubmed
However ,
BAdV-3 infection of cells transfected with 100K - enhanced yellow fluorescent protein - expressing plasmid detected fluorescent protein in the nucleus of the cells , suggesting that other viral proteins may be required for the nuclear localization of 100K. -
pubmed
Several studies have used window of opportunity in
breast cancer patients before neoadjuvant chemotherapy to correlate gene expression analysis , metabolomics , immunohistochemical markers , and metabolic serum markers with those likely to benefit . -
pubmed
We review the role metabolite measurement , functional imaging and gene sequencing analysis play in elucidating the effects of metabolically targeted drugs in
cancer treatment and determining
patient selection . -
pubmed
BACKGROUND :
Hypoglycemia is concerning in
patients with
diabetes undergoing
hyperbaric oxygen (
HBO2 ) therapy . -
pubmed
RESULTS : During 77 months , 3,136
HBO2 sessions were performed on
patients with
diabetes . -
pubmed
CONCLUSIONS : In
patients with
diabetes undergoing HBO2 , severe
hypoglycemia is rare and occurs more frequently in
Type 1 diabetes . -
pubmed
The
lymphoma cells were also positive for
Epstein - Barr virus by
Epstein - Barr virus - encoded RNA in situ hybridization test . -
pubmed
CLINICAL CASES : We report 5 cases of
patients who experienced intrathoracic
rupture of
hydatic cyst of liver . -
pubmed
This case report supports the feasibility of using this combination therapy early after allo - HSCT for
patients with
HCV infection . -
pubmed
Piperine , a natural compound isolated from the
fruits of
Piper , is known to modulate several neurotransmitter systems such as
serotonin ,
norepinephrine , and
GABA , all of which have been linked to the development of
convulsions . -
pubmed
Fruits of
Piper species have been suggested as means for managing
seizure disorders . -
pubmed
Furthermore the latency for development of
convulsions and mortality rate was recorded in different experimental
mouse models of
epilepsy (
pentylenetetrazole , maximal electroshock ,
NMDA ,
picrotoxin ,
bicuculline ,
BAYK-8644 ,
strychnine - induced
convulsions ) after administration of various doses of
piperine ( 5 , 10 and 20 mg / kg , i.p . ) -
pubmed
BACKGROUND : The
powdery mildew disease affects thousands of plant species and arguably represents the major fungal threat for many Cucurbitaceae crops , including
melon (
Cucumis melo L. ) ,
watermelon (
Citrullus lanatus L. ) and
zucchini (
Cucurbita pepo L. ) . -
pubmed
Gene transfer strategies to the brain have contributed to evaluate in
animal models many interesting tracks , some of which should deserve clinical applications in
AD patients in the future . -
pubmed
Radiation Monitoring Results from the First Year of Operation of a Unique Ambulance - based Computed Tomography Unit for the Improved Diagnosis and Treatment of
Stroke Patients . -
pubmed
To determine if health outcomes of possible
stroke patients can be improved by decreasing the time from symptom presentation to treatment , the first mobile
stroke ambulance unit in the United States was deployed by The University of Texas Health Science Center at Houston ( UTHealth ) in 2014 , equipped with a computed tomography imaging system . -
pubmed
The mobile
stroke unit shortens the time to treatment for
stroke patients by allowing pre - hospital treatment . -
pubmed
This report , based on data from a clinical case , proposes that
pulmonary tumor thrombotic microangiopathy , an underdiagnosed cause of
pulmonary hypertension and
death in
patients with
adenocarcinoma , is a
paraneoplastic syndrome (
PNS ) . -
pubmed
One
patient died of
sepsis and
aspiration pneumonia at 3 months . -
pubmed
Conduction disease accounted for most devices , but 371
patients underwent CIED implantation for secondary prevention of
ventricular arrhythmias . -
pubmed
The limited literature showed comparable
patient HRQOL profiles to those with benign conditions such as
degenerative disc disease . -
pubmed
Treatment of
post - traumatic elbow deformities in
children with the Ilizarov distraction osteogenesis technique . -
pubmed
OBJECTIVE : The present study assessed functional and radiographic outcomes of distraction osteogenesis treatment of
post - traumatic elbow deformities in
children . -
pubmed
METHODS : Eight
children were treated between 2008 and 2013 for
post - traumatic elbow deformities using distraction osteogenesis . -
pubmed
Six
patients had varus and 2 had
valgus deformity . -
pubmed
Mean preoperative varus
deformity in 6
patients was 29.2 and
valgus deformity in 2
patients was 28.5 . -
pubmed
CONCLUSION : Ilizarov distraction osteogenesis is a valuable alternative in treatment of
elbow deformities in
children . -
pubmed
This review will describe the pathophysiology of
cancer pain and general approach in managing a
patient with
lung cancer pain . -
pubmed
Whole Genome Sequence and Comparative Genomics of the Novel
Lyme Borreliosis Causing Pathogen ,
Borrelia mayonii . -
pubmed
Borrelia mayonii , a
Borrelia burgdorferi sensu lato ( Bbsl ) genospecies , was recently identified as a cause of
Lyme borreliosis (
LB ) among patients from the upper midwestern United States . -
pubmed
A high - throughput , modified
ALS activity assay for
Cyperus difformis and
Schoenoplectus mucronatus seedlings . -
pubmed
HCV infection was confirmed by positive results in
HCV antibody ( anti -
HCV ) and
HCV - RNA tests . -
pubmed
However , atypical surface ECGs can also be found in
patients with severe
left ventricular dysfunction and involvement of the right ventricle complicating the diagnosis of bundle branch reentry
VT . -
pubmed
It is important to diagnose bundle branch reentry
VT because
patients with bundle branch reentry
VT may suffer from a high rate of serial implantable cardioverter defibrillator ( ICD ) interventions based on
VT recurrences due to immediate reinitiation of the
arrhythmia . -
pubmed
Nusinersen is globally the first drug approved ( by the US FDA ) for treatment of
SMA in
children and adults . -
pubmed
METHODS : We collected 24 - h urine samples from 114
controls and 71
patients with
adrenal diseases . -
pubmed
Compared with
patients with
adrenocortical adenoma (
ACA ) ,
patients with
adrenocortical carcinoma (
ACC ) had 11
steroids with increased Z scores , especially
tetrahydro-11 - deoxycortisol ( 14 vs 0.5 , P & lt ; 0.001 ) ,
pregnanetriol ( 7.5 vs -0.4 , P = 0.001 ) , and
5 - pregnenetriol ( 5.4 vs -0.4 , P = 0.01 ) . -
pubmed
METHODS : Two German university hospitals with different EVD management regimes ( rapid weaning [ RW ] vs gradual weaning [ GW ] ) pooled the data of their observational cohorts containing altogether 1171 consecutive
SAH patients treated between January 2005 and December 2012 . -
pubmed
RESULTS : The final cohort consisted of 455 and 510
SAH survivors treated in the centers with RW and GW , respectively . -
pubmed
Shunt - dependent
SAH patients undergoing GW required significantly longer time until shunting ( mean 29.8 vs 21.7 d , P & lt ; .001 ) and hospital stay ( mean 39 vs 34.4 d , P = .03 ) . -
pubmed
Danshen , the dried root of
Salvia miltiorrhiza Bunge (
Lamiaceae ) , is one of the traditional Chinese medicines ( TCMs ) most commonly used for the treatment of cardiovascular and
cerebrovascular diseases . -
pubmed
We aimed to determine on
patients with
CAD the relationships between
Trans fatty acids (
Trans FA ) and different
CAD associated parameters such as inflammatory and oxidative stress parameters in addition to Gensini score as a vascular severity index . -
pubmed
METHODS :
Fatty acid profiles were established by gas chromatography from 111
CAD patients compared to 120 age - matched control group . -
pubmed
Plasmatic and erythrocyte
Trans FA were also increased in
CAD patients compared to controls . -
pubmed
The measurement of these
Trans FA would be of great value for the screening of
lipid metabolism disorders in
CAD patients . -
pubmed
METHODS : A total of 103
depressive patients and 32 healthy
subjects were assessed . -
pubmed
According to HAMD-17scores , 51 , 18 , and 34
patients were enrolled in the mild
depression , moderate
depression , and severe
depression groups , respectively . -
pubmed
Toxicity of
plant extracts containing
pyrrolizidine alkaloids using alternative invertebrate models . -
pubmed
Introduction :
Lyme disease is a
tick - borne illness caused by the spirochete
Borrelia burgdorferi and is widely reported in the USA , Central Europe , South East Asia and Latin America . -
pubmed
The Physical and Neurological Examination of Subtle Signs was preliminarily examined for sensitivity to motor changes in a pilot cohort of
adolescents aged 13 - 17 yrs with sports - related
concussion . -
pubmed
A total of 15
adolescents ( 5 female
adolescents ) with sports - related
concussion were evaluated up to three times : within 2 wks of
injury , approximately 1 mo later ( mean , 35 days between visits ) , and for those not recovered at the second visit , again after clinical recovery ( mean , 70 days between the first and last visits for all participants ) . -
pubmed
Efficacy of Idursulfase therapy in
patients with
Mucopolysaccharidosis type II who initiated enzyme replacement therapy in adult age . -
pubmed
BACKGROUND : Enzyme replacement therapy ( ERT ) has been shown to decrease urine glycosaminoglycans ( uGAGs ) and liver and spleen volumes , and to improve clinical symptoms in
mucopolysaccharidosis type II (
MPS - II )
patients . -
pubmed
CONCLUSIONS : ERT improves uGAGs and liver / spleen volume with a moderate evidence level in
MPS - II patients initiating therapy as adults , although the putative associated clinical benefit is unclear . -
pubmed
Real life efficacy and safety of this combination were evaluated in
HCV GT1b infected patients ( mostly cirrhotics ) with compensated
liver disease who failed previous
boceprevir or
telaprevir based therapies more than a year before . -
pubmed
Material and methods : Data of previous
protease inhibitor failure patients , treated with
3DAA+
RBV for 12 weeks ( GT1b and/or non - cirrhotics ) or 24 weeks ( non - GT1b cirrhotics ) , were retrospectively collected . -
pubmed
Conclusions : One year after previous failure of
boceprevir or
telaprevir based therapy , 12 weeks of
3DAA+
RBV combination in
HCV GT1b infected
patients is similarly effective and safe as in those with no previous
HCV therapy , even in the presence of
cirrhosis . -
pubmed
Not all
kidney disease in
patients with
diabetes is
diabetic nephropathy . -
pubmed
Gualoupi (
Pericarpium Trichosanthis ) injection in combination with convention therapy for the treatment of
angina pectoris : a Meta - analysis . -
pubmed
OBJECTIVE : To use a Meta - analysis to review the efficacy and safety of Gualoupi (
Pericarpium Trichosanthis)injection ( PTI ) in the treatment of
angina pectoris . -
pubmed
MATERIAL / METHODS : Thirty adult
subjects clinically and radiographically diagnosed with
knee osteoarthritis , who were not previously subjected to any treatment , were enrolled . -
pubmed
METHODS : A total of 1444
women with
EC were identified . -
pubmed
Of which we extracted
women with locoregional and distant
recurrence or with distant
recurrence alone . -
pubmed
RESULTS : 110
women developed distant metastatic
disease with ( n = 37(33.6 % ) ) or without ( n = 73(66.4 % ) ) locoregional
recurrence , including 39
women with exclusive first site of metastatic
disease and 34
women with multiple sites of metastatic
disease . -
pubmed
When considering all
women , the most common exclusive first site of
metastasis was lung ( 42.8 % ) . -
pubmed
These data support current clinical practice of screening for site - specific
metastatic disease after initial treatment of early stage
EC based on concerning
women - specific signs or symptoms . -
pubmed
We performed a systematic review and meta - analysis of studies investigating vessel density ( VD ) in
patients with
glaucoma using OCTA . -
pubmed
Camembert cheese was manufactured from milk contaminated with pathogenic and nonpathogenic
strains of
Escherichia coli . -
pubmed
Human epidemiological studies suggested that
vitamin D3 deficiency might increase
glioma incidence , but molecular mechanism is less understood . -
pubmed
The most frequent ailment for which antibiotics are prescribed is
otitis media ( ear infections ) , which is most commonly caused by
Haemophilus influenzae ,
Moraxella catarrhalis , and
Streptococcus pneumoniae Treatment of
otitis media is complicated by the fact that the bacteria in the middle ear typically form biofilms , which can be recalcitrant to antibiotic treatment . -
pubmed
Furthermore , bacterial
respiratory infections can be greatly exacerbated by
viral coinfection , which is particularly evidenced by the synergy between
influenza and
S. - pubmed
pneumoniae In this study , we sought to ascertain the in vivo efficacy of
aminomethyl spectinomycin lead 1950 , an effective antibacterial agent both in vitro and in vivo against
Streptococcus pneumoniae in the context of complex
respiratory infections and
acute otitis media . -
pubmed
BACKGROUND : The aim of this study was to evaluate the role of the skeletal muscle mass index ( SMI ) for major postoperative morbidity in
patients with
Crohn ' s disease (
CD ) and intestinal surgery at a tertiary referral center . -
pubmed
METHODS : A retrospective analysis of the prospectively maintained database for surgical
patients with
CD at our institution was performed . -
pubmed
Major
postoperative complications were observed in 32
patients ( 13.9 % ) . -
pubmed
Anticarcinogenic potential of gold nanoparticles synthesized from
Trichosanthes kirilowii in
colon cancer cells through the induction of apoptotic pathway . -
pubmed
This protocol afforded well - defined nanoparticles possessing a drug loading of approximately 7 % w / w. The resulting
Nal - cNPs demonstrated excellent biocompatibility , while exhibiting sustained linear release kinetics in vitro and blocking the effects of high dose ( 10 mg / kg ) acute
morphine for up to 98 h in an in vivo
rodent model of
neuropathic pain . -
pubmed
Furthermore , 10
patients in Group B had
SCL , compared with none in Group A ( p = 0.004 ) . -
pubmed
Only 4
patients ( 7 % ) cited postoperative activity limitations as being caused by
hip pain . -
pubmed
All
patients were followed regarding treatment response , treatment duration , and presence of
relapse . -
pubmed
Prognosis was good for all
patients , but
relapse was significantly more frequent in the high SP - D group ( 6 cases ) than in the normal SP - D group ( 0 cases ; P = 0.049 ) . -
pubmed
Pseudomonas aeruginosa exhibits resistance against many antibiotics and causes a variety of
infections in immunocompromised individuals and especially in those with
burn wounds and
lung infections . -
pubmed
Triflumuron induces
genotoxicity in both
mice bone marrow cells and
human colon cancer cell line . -
pubmed
To reach this purpose , our study aimed to elucidate the eventual
genotoxic effects of
TFM in
mice bone marrow cells and in
HCT 116 cells after a short term exposition . -
pubmed
TFM was administered intraperitoneally to Balb / C male
mice at doses of 250 , 350 and 500 mg / kg bw for 24 h.
Genotoxicity was monitored in bone marrow cells using the comet test , the micronucleus test and the
chromosome aberration assay . -
pubmed
This
genotoxicity was confirmed also in vitro on
human intestinal cells
HCT 116 using the comet test . -
pubmed
PURPOSE : To test the effectiveness ( Participant A ) and tolerability ( Participant B ) of
urinary stone comminution in the first - in -
human trial of a new technology , burst - wave lithotripsy ( BWL ) , Materials and Methods : An investigational BWL and ultrasonic propulsion system was used to target a 7 - mm
kidney stone in the operating room prior to ureteroscopy ( Participant A ) . -
pubmed
CONCLUSIONS : The first - in -
human tests of BWL
pulses were successful in that a
renal stone was comminuted in under 10 minutes , and BWL was also tolerated by an awake subject for a distal ureteral stone . -
pubmed
We report a case of a
patient with
brain stem cavernous malformations presented as pure
COPS with additional sensory disturbance in the thorax . -
pubmed
We included 202
patients ( 73.48 + - 13.1 years ) with various systemic
metabolic disorders for training of the DNN model , and the following groups for validation of the model : ( 1 )
Patient group , 65
patients ( 73.6 + - 11.0 years ) who were hospitalized for rehabilitation after
stroke ; ( 2 ) Healthy group , 37 subjects ( 62.0 + - 8.6 years ) ; ( 3 ) Health examination group , 165 subjects ( 54.0 + - 8.6 years ) admitted for a health examination . -
pubmed
METHODS : The effect of
moclobemide on
seizures was assessed in the electroconvulsive threshold test , while its influence on antiepileptic drugs was estimated in the maximal electroshock test in
mice . -
pubmed
So far as the results of experimental studies can be transferred to clinical conditions ,
moclobemide seems safe for the application in
patients with
epilepsy and
depression . -
pubmed
Angiographic evaluation of
patients with
chronic gastrointestinal bleeding . -
pubmed
The compound was mutagenic in both tester
strains used , namely
TA98 and TA100 . -
pubmed
The clinical picture and treatment of exacerbated chronic
respiratory insufficiency is studied in 189
silicosis patients with different stage and degree of decompensation . -
pubmed
It is found out that chronic
respiratory insufficiency determination in these
patients is conditioned by the exacerbation of a chronic inflammtory process in the bronchi and lungs ( 68.2 per cent ) , or by intercurrent acute inflammtory pulmonary process ( 15.9 per cent ) . -
pubmed
Lethality in
patients with III degree
silicosis amounts to 8,2 per cent , and in
patients with III degree
respiratory insufficiency -- to 30.7 per cent . -
pubmed
A complex active therapy program for
silicosis patients with exacerbated chronic
respiratory insufficiency is proposed . -
pubmed
Using an in vitro quantitative clonal culture technique of bone marrow granulocyte - macrophage progenitor cells ( colony - forming units culture ( CFU - c ) ) , we studied the
hematopoietic toxicity of
azathioprine after unilateral and bilateral ureteral ligation , unilateral and bilateral nephrectomy , and splenectomy in
C57BL / 6 mice . -
pubmed
When the
ocular toxicity and the in vivo and in vitro effects of
gentamicin ,
Nebcin , and saline solution were compared in experimentally induced
Pseudomonas keratitis in
rabbits , both antibiotics showed the same
toxicity for the
rabbits ' conjunctival tissues . -
pubmed
Two hundred sixty - seven
strains of
Pseudomonas aeruginosa isolated from clinical specimens were immunotyped using seven anti -
Pseudomonas rabbit sera , and pyocin typed using eight indicator
strains . -
pubmed
An approach to effective therapy for
patients suffering such reactions should be based on our latest understanding of the pathophysiology of this
syndrome . -
pubmed
This study comprised 12
patients admitted for interpleural catheter treatment of chronic
pancreatic pain . -
pubmed
Catheters were left in situ for 12 - 30 h. Immediate
pain relief was achieved in all
patients . -
pubmed
Five
patients had only a single blockade offering
pain relief for a median of 33 days . -
pubmed
One
patient suffering from
pancreatic carcinoma remained
pain - free until
death 45 days later . -
pubmed
After this second blockade long - lasting
pain relief was achieved in three
patients for 70 , 105 and 145 days . -
pubmed
Two
patients experienced
pain relief lasting 11 - 14 days , while in two
patients only a short - lived effect was observed , 3 - 8 days . -
pubmed
Unimportant
pneumothorax occurred in one
patient . -
pubmed
We consider interpleural blockade an alternative worth further investigations in the future in the treatment of
patients suffering from chronic
pancreatic pain . -
pubmed
It is known that consumption of
cruciferous vegetables protects against the chemical induction of
cancer in many organs . -
pubmed
The use of
sufentanil in neuroanesthesia has been questioned because of a potential
increase in intracranial pressure ( ICP ) in
dogs and
humans . -
pubmed
Toxoplasmosis in
sheep ,
goats and
cattle in central Ethiopia . -
pubmed
In a seroepidemiological survey using an indirect haemagglutination assay , the prevalence rate of
toxoplasmosis in central Ethiopia was 22.9 % of 899
sheep , 11.6 % of 753
goats and 6.6 % of 785
cattle . -
pubmed
Favorable effects of
prostacyclin infusion in a
patient given a renal transplant and with severe
vascular disease secondary to
diabetes -- a case report . -
pubmed
Microangiopathy is one of the most frequent diseases in
diabetic patients . -
pubmed
A
diabetic man with a kidney transplant and with severe and progressive
vasculopathy with early
necrosis of the fingers and toes was submitted to three
prostacyclin (
PGI2 ) intravenous infusions ( 5 ng / kg / min for forty - eight hours ) during a period of two months . -
pubmed
Combination of parenteral and oral immunotherapy in grass pollen -
allergic children . -
pubmed
The psychological care of
children with
malignant disease . -
pubmed
Cholesterol esterification and net mass transfer of
cholesterylesters and
triglycerides in plasma from healthy subjects and hyperlipidemic
coronary heart disease patients . -
pubmed
A three - year clinical comparison of a
sodium monofluorophosphate dentifrice with
sodium fluoride dentifrices on
dental caries in
children . -
pubmed
Human tissues (
keloid , small bowel , lung ) were fixed in either Carnoy 's fluid or neutral buffered
formalin . -
pubmed
Normotensive
rats were adrenalectomized or sham - operated and made
hypertensive with
methylprednisolone acetate ( 20 mg / kg s.c . -
pubmed
[ Blood serum analyses in
cow herds with
fertility disturbances ] . -
pubmed
Toxicity in the
dog of inhaled 90 Y in fused clay particles : early biological effects . -
pubmed
Respiratory tract carcinogenesis induced in
hamsters by different dose levels of
benzo -( a ) pyrene and
ferric oxide . -
pubmed
Effect of
fluorides on
root resorption in replanted
rat molars . -
pubmed
Arthritis was produced in
rats by the intravenous injection of
Mycoplasma arthritidis . -
pubmed
An avirulent
strain of
M. - pubmed
arthritidis and a
strain previously classified as
M. - pubmed
Fractionation of
Marek ' s disease virus - induced
lymphoma by velocity sedimentation and association of infectivity with cellular fractions with and without
tumor antigen expression . -
pubmed
Cell suspensions of
lymphomas induced by
Marek ' s disease ( MD ) virus were fractionated by sedimentation at unit gravity on a continuous gradient of
bovine fetal serum . -
pubmed
Growth and maturation of
children with
insulin - dependent diabetes mellitus . -
pubmed
A 67 - year - old
man had a spontaneous
intrastromal iris hemorrhage which resolved without complications . -
pubmed
Evaluation of the safety of
metoclopramide in
patients with
gastroesophageal reflux disease . -
pubmed
The long - term safety of
metoclopramide was evaluated for up to 30 months in 269
patients with chronic symptoms of
gastroesophageal reflux disease . -
pubmed
Tympanosclerosis of the ear drum in
children with
SOM differs from normal ear drums in
children with
SOM . -
pubmed
Profound
calcification could only be found in
children with
tympanosclerosis coexisting with
chronic perforation of the ear drum . -
pubmed
Among 2493
patients undergoing cerebral angiography 43
children were found to have
cerebrovascular occlusion . -
pubmed
Fifty - six
patients who had undergone salvage surgery for residual or recurrent
squamous carcinomas of the tongue between 1967 and 1977 were reviewed . -
pubmed
The tongue or cervical lymph nodes were involved in 27 of the 28
patients who died with recurrent
tumour . -
pubmed
By treatment with high dose
prednisolone and intense supportive therapy the
patient underwent complete remission of
AIL with preservation of the remaining renal function . -
pubmed
From 1984 to 1989 , 354
patients with a diagnosis of
testis tumor were referred to the Oncology Hospital , Ankara , Turkey , for therapy . -
pubmed
Histologic diagnoses were typical
seminoma in 33
patients ,
anaplastic seminoma in two
patients and
spermatocytic seminoma in only one
patient . -
pubmed
Reduced dose
PVB chemotherapy can be successfully and safely used as the primary treatment of choice in
patients with
Stage IIC - IV testicular seminoma . -
pubmed
Two elderly
patients with
polymyalgia rheumatica (
PMR ) , one with and the other without
temporal arteritis (
TA ) , are presented . -
pubmed
Intraoperative complications of laparoscopic surgery are mostly due to
traumatic injuries sustained during blind trocar insertion and physiological changes associated with
patient positioning and
pneumoperitoneum creation . -
pubmed
Laparoscopic cholecystectomy is a major advance in the management of
patients with symptomatic
gall - bladder disease . -
pubmed
We reviewed 22 epidermoid and 10
dermoid tumours of the skull and brain from
patients operated on consecutively at Henry Ford Hospital between 1975 and 1991 . -
pubmed
The average age at presentation was 35 years for
patients with
epidermoids and 15 years for those with
dermoids . -
pubmed
Common clinical presentations for
patients with intradural lesions included
headache ,
visual deficits , and
seizures , whereas
patients with
extradural lesions harbored asymptomatic
scalp masses . -
pubmed
Overall , with the intradural
tumours we had good to excellent results in 17
patients ( 90 % ) , poor results in 1 ( 5 % ) , and 1
death ( 5 % ) . -
pubmed
Re - operation was needed in 5 intradural
recurrences ( 26 % ) with deterioration in only one
patient 's neurologic status postoperatively . -
pubmed
Indices of heterogeneity in mosquito susceptibility to
infection indicated that gene frequencies determining susceptibility fluctuated with time in all species , except
A. - pubmed
Salmonella enteritidis 27655 - 3b and a few diarrheagenic
Escherichia coli strains produce morphologically and antigenically related , thin , aggregative fimbriae , collectively named GVVPQ fimbriae ( S. K. Collinson , L. Emody , T. J. -
pubmed
enteritidis
strains and six
E. - pubmed
Treatment of
pulmonary congestion and control of heart rate in
patients with
atrial fibrillation remain major medical goals . -
pubmed
Percutaneous balloon commissurotomy is preferred for most
patients with predominant
mitral stenosis and for those with contraindications to valve replacement . -
pubmed
Implantation of a prosthetic valve is best for
patients with significant
mitral regurgitation ,
multivalve disease , associated
coronary artery disease that requires bypass , or
mitral valve deformity too severe to allow adequate balloon commissurotomy . -
pubmed
Newborns were highly
hypoxemic at admission and all but one underwent rescue cannulation . -
pubmed
Atrial fibrillation in
acute myocardial infarction : a prospective study based on data from a consecutive series of
patients admitted to the coronary care unit . -
pubmed
Ischaemia --
reperfusion injury in the
rat is modulated by
superoxide generation and leads to an augmentation of the
hypoxic pulmonary vascular response . -
pubmed
The study population was 21
women with suspected
placental insufficiency ; one woman was excluded because of a positive OCT with reactive fetal heart rate pattern . -
pubmed
Late virus replication events in microglia are required for neurovirulent retrovirus - induced
spongiform neurodegeneration : evidence from neural progenitor - derived chimeric
mouse brains . -
pubmed
CasBrE is a neurovirulent
murine retrovirus which induces a
spongiform myeloencephalopathy in susceptible
mice . -
pubmed
The role of
calcium ions entering cells upon both reperfusion and previous
ischemia for reperfusion
arrhythmias has been studied on the experimental model of isolated
rat right ventricle perfused through coronary artery . -
pubmed
Up to 65 % of elderly hospitalized
patients are protein - energy undernourished at admission or acquire
nutritional deficits while hospitalized . -
pubmed
Calcium binding to polypeptides of
rat liver and Zajdela
hepatoma mitochondrial inner membranes . -
pubmed
Large intravenous
bilirubin loads increase the
cytotoxicity of bile and lower the resistance of the canalicular membrane to
cytotoxic injury and cause
cholestasis in
pigs . -
pubmed
METHODS : The
cytotoxicity of bile was assayed against
pig erythrocytes before and throughout 4.5 - h intravenous infusion of 170 microg kg(-1 )
body weight of
bilirubin in anaesthetized
pigs . -
pubmed
The
abnormal behaviors induced by
methamphetamine (
MAP : 1 mg / kg ) or
phencyclidine (
PCP : 10 mg / kg ) were measured using behavioral analysis following the microinjection of one of three
calcium (
Ca ) antagonists (
nifedipine :
Nif ,
nicardipine :
Nic and
flunarizine :
Flu ) into the
rat caudate putamen or amygdala . -
pubmed
Computed tomography of cholesterinic
granulomas in the choroid plexus of
horses . -
pubmed
Cholesterinic
granulomas are
tumor - like masses in the choroid plexuses of
horses . -
pubmed
This report describes the computed tomographic findings in four
horses with cholesterinic
granulomas , including the clinical and the pathologic features . -
pubmed
All four
horses had bilateral cholesterinic
granulomas in the lateral ventricles . -
pubmed
METHODS : Between 1995 and 1998 , we performed an interventional radiological treatment in five
patients with
idiopathic portal hypertension , four of whom had refused surgery and one of whom had undergone surgery . -
pubmed
Three
patients with
gastroesophageal varices (
GEV ) were treated by partial splenic embolization ( PSE ) , one
patient with
esophageal varices (
EV ) and massive
ascites by transjugular intrahepatic portosytemic shunt ( TIPS ) and PSE , and one
patient with GEV by percutaneous transhepatic obliteration ( PTO ) . -
pubmed
RESULTS : In one
woman with severe
GEV who underwent three sessions of PSE , there was endoscopic confirmation that the GEV had disappeared . -
pubmed
PTO for GV in one
patient resulted in good control of the
varices . -
pubmed
All
patients have survived for 16 - 42 months since the first interventional treatment , and
varices are well controlled . -
pubmed
CONCLUSION : Interventional radiological treatment is effective for
patients with
idiopathic portal hypertension , whether or not they have undergone surgery . -
pubmed
Estrogen synthesis in
human colon cancer epithelial cells . -
pubmed
Genetic evidence for
obesity loci involved in the regulation of body fat distribution in
obese type 2 diabetes rat , OLETF . -
pubmed
The Otsuka Long - Evans Tokushima Fatty ( OLETF )
rat is an
animal model for
obese type 2 diabetes in
human . -
pubmed
Obesity is essential for the onset of
type 2 diabetes in this
rat . -
pubmed
Our present investigation was designed to identify quantitative trait loci ( QTLs ) contributing to
obesity by performing a whole - genome search using 214 F(2 ) intercross progeny between OLETF and F344
rats . -
pubmed
The CBA / N
strain carries xid , a
murine btk missense mutation that reduces peripheral B cell numbers . -
pubmed
We report a case study of a
patient with
bilateral amygdaloid damage who , despite a severe deficit in interpreting facial expressions of emotion including fear , exhibits an intact ability to express this and other basic emotions . -
pubmed
Resistance of
Pseudomonas aeruginosa isolates to hydrogel contact lens disinfection correlates with
cytotoxic activity . -
pubmed
One of the most common pathogens in
infection of hydrogel contact lens wearers is
Pseudomonas aeruginosa , which can gain access to the eye via contamination of the lens , lens case , and lens care solutions . -
pubmed
Resistance to disinfection appeared to be an inherent rather than acquired trait , since some resistant
strains had been isolated prior to the introduction of the disinfectants and some susceptible
P. - pubmed
At the follow - up , 290
children still had
headache , 101 were in clinical remission , and 51 had dropped out . -
pubmed
Broccoli sprouts are a rich source of
glucosinolates and
isothiocyanates that induce phase 2 detoxication enzymes , boost antioxidant status , and protect animals against chemically induced
cancer . -
pubmed
Antiplasmodial activities of some Ghanaian plants traditionally used for
fever /
malaria treatment and of some alkaloids isolated from
Pleiocarpa mutica ; in vivo antimalarial activity of
pleiocarpine . -
pubmed
Fourteen Ghanaian plants used in folk medicine to treat
fever /
malaria were screened for activity against
Plasmodium falciparum ( strain K1 ) and were tested for general toxicity to the
brine shrimp . -
pubmed
Possible
toxicity due to
U. - pubmed
Although ( 1 ) was inactive against
malaria parasites in vitro , it was moderately active against
P. - pubmed
berghei in
mice ( 25 mg kg(-1 ) daily for 4 days reduced
parasitaemia by 28.5 % compared to untreated controls ) . -
pubmed
The present report describes 3
patients with
systemic lupus erythematosus who developed typical symptoms of acquired
angioedema , characterized by recurrent swelling of subcutaneous and mucous tissues . -
pubmed
MATERIALS AND METHODS :
PJ34 ( at doses of 0.03 - 30 mg / kg ) was tested in
rats and
mice subjected to standard models of
inflammation , with relevant parameters of
inflammation measured using standard methods . -
pubmed
PJ34 treatment ( oral gavage ) induced a significant suppression of the inflammatory response in dextran sulfate
colitis , multiple low dose
streptozotocin diabetes and
cyclophosphamide - accelerated
autoimmune diabetes in the non - obese
diabetic mice , and reduced the degree of mononuclear cell infiltration into the iris in an endotoxin - induced
uveitis model . -
pubmed
OBJECTIVES : To identify which
children with
acute otitis media are at risk of poor outcome and to assess benefit from antibiotics in these children . -
pubmed
RESULTS : Distress by day three was more likely in
children with high temperature ( adjusted odds ratio 4.5 , 95 % confidence interval 2.3 to 9.0 ) ,
vomiting ( 2.6,1.3 to 5.0 ) , and
cough ( 2.0 , 1.1 to 3.8 ) on day one . -
pubmed
Among the
children with high temperature or
vomiting , distress by day three was less likely with immediate antibiotics ( 32 % for immediate v 53 % for delayed , chi2=4.0 ; P=0.045 , number needed to treat 5 ) as was night disturbance ( 26 % v 59 % , chi2=9.3 ; P=0.002 ; number needed to treat 3 ) . -
pubmed
In
children without higher temperature or
vomiting , immediate antibiotics made little difference to distress by day three ( 15 % v 19 % , chi2=0.74 ; P=0.39 ) or
night disturbance ( 20 % v 27 % , chi2=1.6 ; P=0.20 ) . -
pubmed
CONCLUSION : In
children with
otitis media but without
fever and
vomiting antibiotic treatment has little benefit and a poor outcome is unlikely . -
pubmed
We have examined the pattern of four radiation - related
neoplasms in a radiation - exposed cohort of 2795
patients . -
pubmed
A severe model of
mesenteric ischemia and reperfusion was produced by subjecting
mice to 45 min occlusion followed by reperfusion of the superior mesenteric artery and celiac trunk . -
pubmed
The aim of this paper is to review new developments in the intensive care of
patients with space - occupying
middle cerebral artery infarctions . -
pubmed
Corticoids and
hemodilution are obsolete therapies in these
patients . -
pubmed
To minimize
hypertension and provide reversibility , 24
red wolves were immobilized using three
medetomidine -
butorphanol ( MB ) combinations without the use of
ketamine in the initial injection . -
pubmed
The heart rate was similar among the three groups for the first 30 min , and marked
bradycardia was noted in one
wolf from each group . -
pubmed
The
MBK30 wolves had significant elevations in heart rate and transient
hypertension after intravenous
ketamine administration . -
pubmed
Most
wolves had mild to moderate
metabolic acidemia . -
pubmed
STUDY DESIGN : We reviewed the clinical data of 98
patients with
ICC who underwent resection at Seoul National University Hospital from 1980 to 1998 . -
pubmed
In the developing
rat hippocampus , ictal
epileptiform activity can be elicited easily in vitro during the first three postnatal weeks . -
pubmed
Based on the theories of accumulated temperature and on the physio - ecological characteristics of
Medicago sativa , a simulation model for its growth under soil
water stress in arid sandy region was developed . -
pubmed
Intracellular
magnesium of platelets in
children with
diabetes and
obesity . -
pubmed
By using a fluorescent probe , mag -
fura-2 , we examined the basal levels and changes in intracellular
Mg ( 2 +)([ Mg ( 2 +)]( i ) ) of platelets in
diabetic and
obese children . -
pubmed
The
diabetic patients and
obese subjects have [
Mg ( 2 +)]( i ) deficiency . -
pubmed
Macrometastases ( dimensions greater than 2 mm ) were found in 19
patients . -
pubmed
In another seven of these
patients ( 36.8 % ) ,
macrometastases were found in
SLNs with radioactive levels lower than 51 % of that of the hottest node . -
pubmed
Cell
death unlikely contributes to
taxol production in fungal elicitor - induced cell suspension cultures of
Taxus chinensis . -
pubmed
Cell suspension cultures of
Taxus chinensis , with 20 , 40 and 100 mg fungal elicitor l(-1 ) from
Aspergillus niger , underwent rapid cell
death after 24 h , which was about 2 , 3.7 and 5 - fold of that of the control . -
pubmed
O2 - free N2 inhibited cell
death but had little effect on
Taxol production as induced by 40 mg
fungal elicitor l(-1 ) . -
pubmed
Chicken - pox is one more newer vaccine in our armamentarium against
infectious diseases . -
pubmed
Anti gizzard
ulcer factors in the treatment of
gastric ulcer in
man ; a review . -
pubmed
[ USE OF
AMINAZIN IN THE TREATMENT OF
PNEUMONIA IN YOUNG
CHILDREN ] . -
pubmed
[ DIAGNOSIS , THERAPY , DOCUMENTATION AND CLINICAL EVALUATION OF 360
WOMEN WITH
NEOPLASTIC DISEASE IN GYNECOLOGICAL DIVISION OF A STATE HOSPITAL ] . -
pubmed
Action of antiinflammatory agents on endotoxin - induced
lung inflammation in
mice . -
pubmed
Anaesthesia in elderly
patients with
neurodegenerative disorders : special considerations . -
pubmed
Neurodegenerative diseases are increasingly common in elderly
patients , who present a particular anaesthetic challenge . -
pubmed
The majority of
people over the age of 70 years have some degree of
cerebral atrophy . -
pubmed
Levodopa ,
bromocriptine and tricyclic antidepressants are known to cause
orthostatic hypotension in
patients with
neurodegenerative disease . -
pubmed
For induction of general anaesthesia
propofol is a suitable agent in
patients with
neurodegenerative disease due to its rapid metabolism , but may not be suitable in
patients with
Parkinson ' s disease as it can induce spontaneous
involuntary movements . -
pubmed
Regional anaesthesia may , however , have significant advantages in
patients with
Parkinson ' s disease , who can continue to take oral
levodopa preoperatively , during surgery , if required , and early in the postoperative period . -
pubmed
Anti - emetic drugs such as
phenothiazines ,
butyrophenones and
metoclopramide should be used carefully in the postoperative period in these
patients as their antidopaminergic effects may induce or exacerbate
parkinsonian effects . -
pubmed
PATIENTS : Seventy - seven
children ( mean age , 6.5 years ; range , 6 months-16 years ) referred consecutively for
sexual abuse evaluation between July 1999 and June 2002 were included . -
pubmed
A
patient presented with
hypertension ,
hypokalemia , and a 1.2 - cm
left adrenal tumor . -
pubmed
The controlled - environment chamber : a new
mouse model of
dry eye . -
pubmed
CONCLUSIONS : This study indicates that exposure of normal
mice to a low - humidity environment in a CEC can lead to significant alterations in tear secretion , goblet cell density , and acquisition of
dry eye - related ocular surface signs . -
pubmed
OBJECTIVES : To report an unusual presentation of a
spinal cord injury , examine the approach to reversal of the
injury , and review the treatment and management controversies of acute cervical facet dislocations in specific
patient subgroups . -
pubmed
CONCLUSIONS : This case report highlights the advantages and shows some safety concerns regarding immediate , closed traction reduction of cervical facet dislocation with real - time neural monitoring in an awake , alert , oriented , and appropriately select
patient before MRI studies in the setting of preexisting
central stenosis from
OPLL . -
pubmed
NE-4C stem cells , however , did not migrate towards the
tumour , if implanted near to
Gl261 tumours established in the adult
mouse forebrain . -
pubmed
Evaluation of microarray analysis for predicting treatment responsiveness in
patients with
chronic hepatitis C viral infection . -
pubmed
More than one sleep pathology may be present in a particular
patient , and these disorders may interact to increase the severity or prolong the duration of
sleep disturbance . -
pubmed
Expression of
carbohydrate antigens in
human esophageal squamous cell carcinoma : prognostic application and its diagnostic implications . -
pubmed
In this study , the relevance of
carbohydrate antigen expression profile was examined in
esophageal squamous cell carcinoma together with prognosis in 130
patients . -
pubmed
The 5 - year survival rate of
patients was found to be associated with expression of
sialyl Le ( a ) and
sialyl Le ( x ) antigens and with
MVD ; thus , all of them were revealed to be independent prognostic factors . -
pubmed
Correlation between carotid area calcifications and
periodontitis : a retrospective study of digital panoramic radiographic findings in pretreatment
cancer patients . -
pubmed
In 10 randomized controlled trials involving 2,602
patients , no incidence of
stent fracture was recognized or reported . -
pubmed
The angiograms of all 530
patients who underwent repeat angiography were analyzed to identify the presence of
stent fracture . -
pubmed
RESULTS : Stent
fracture was identified in 10
patients . -
pubmed
Adverse clinical outcomes associated with
stent fracture occurred in 7
patients ( 6
patients had binary restenosis and 1
patient had stent
thrombosis ) , all necessitating repeat intervention . -
pubmed
OBJECTIVE :
Leishmania tropica is the causative agent of
anthroponotic cutaneous leishmaniasis (
CL ) in Iran . -
pubmed
The therapeutic effect and the efficiency of a new method for the extraction of a removable metallic stent were examined in three
patients treated for
oesophageal perforation . -
pubmed
Two of the three
patients were dilated with a balloon catheter because of corrosive
oesophageal stenosis , and the oesophagus was perforated . -
pubmed
PATIENTS AND METHODS : Prevalence of major International
AIDS Society - USA
HIV-1 drug resistance mutations was measured over calendar years in a population with treatment failure and undergoing resistance testing . -
pubmed
The current report addresses the complex genotype - phenotype interactions in an
azoospermic man . -
pubmed
OBJECTIVES : To evaluate the efficacy , safety and tolerability of
aliskiren in elderly
patients ( & gt ; or = 65 years old ) with
essential hypertension . -
pubmed
METHODS : In this double - blind , multicenter study , 355 elderly
patients with
hypertension [ office mean sitting
systolic blood pressure ( msSBP ) & gt ; or = 145-<180 mmHg and mean 24 - h ambulatory systolic BP ( ASBP ) & gt ; or = 135 mmHg ] were randomized to once - daily treatment for 8 weeks with
aliskiren 75 mg ( n = 91 ) , 150 mg ( n = 84 ) , 300 mg ( n = 94 ) or the comparator
lisinopril 10 mg ( n = 86 ) . -
pubmed
A 71 - year - old
man was admitted to our hospital because of
constipation and
bloody stool . -
pubmed
After IR , myocardial apoptosis and
infarct size were significantly reduced in hearts of exercised
animals compared with sedentary controls . -
pubmed
Antinociceptive activity of
Buddleja globosa ( matico ) in several models of
pain . -
pubmed
ETHNOPHARMACOLOGICAL RELEVANCE : Leaf extracts of
Buddleja globosa ( Buddlejaceae ) are used in Chilean folk medicine for
wound healing . -
pubmed
METHODS AND RESULTS :
Patients with
AF undergoing electrical cardioversion were randomized to receive
candesartan 8 mg once daily ( n = 58 ) or matching placebo ( n = 66 ) and no additional class I or III anti -
arrhythmic drugs . -
pubmed
Risk for
AF recurrence was similar in
patients with low ( 64 % ) , intermediate ( 75 % ) , or high on - treatment rates ( 63 % , P = 0.446 ) and was also independent of
candesartan effects on the fibrillatory rate . -
pubmed
CONCLUSION : In
patients with persistent
AF ,
candesartan decreases the fibrillatory rate , but this effect is restricted to
patients with high baseline fibrillatory rates and is not associated with improved cardioversion outcome . -
pubmed
We describe the case of a
child ( " S " ) who was treated with radiation therapy at age 5 for a recurrent
malignant brain tumor . -
pubmed
Twelve
patients had very large or multicentric
glioblastoma multiforme with a poor performance status and received
TMZ plus radiation doses of 45 - 50.4 Gy . -
pubmed
Twenty - three
patients would have been eligible for randomisation in the European Organisation for Research and Treatment of
Cancer / National Cancer Institute of Canada ( EORTC / NCIC ) trial comparing combined and adjuvant
TMZ plus radiation against radiotherapy alone . -
pubmed
METHODS : The case histories and MR / MR angiography findings of 4
patients with
PCAH were examined . -
pubmed
GOALS : Compare
patient characteristics and outcome and also physician referral patterns between surgically and nonsurgically managed
patients with
pancreatic pseudocysts . -
pubmed
PATIENTS : All
patients treated for
pancreatic pseudocyst between 1999 and 2005 were identified in our health services database . -
pubmed
Patients treated surgically and endoscopically were similar in terms of age ( 49 vs. 52 y ) , mean
cyst diameter ( 9.1 vs. 9.5 cm , P=0.74 ) , incidence of
chronic pancreatitis ( 50 % vs. 32 % , P=0.26 ) and complicated
pancreaticobiliary disease ( 69 % vs. 60 % ) . -
pubmed
Human glioblastoma is well known for its capacity to interfere with effective antitumor immune responses . -
pubmed
The paper evaluates the intensity of
peritoneal adhesions induced by
talc administration on
Wistar rats , alone and in association with different other substances . -
pubmed
Emphasis is placed on unbalanced diets excluding meat , by increasing the consumption of bread and
cereals , which is a universal factor for the development of
visceral diseases . -
pubmed
These studies will be helpful in the diagnosis as well as follow up of
patients with
cardiac amyloidosis . -
pubmed
OBJECTIVE : To determine the implications of the presence of
hyperglycemia after a cardiac surgical procedure in
patients with no history of
diabetes mellitus (
DM ) . -
pubmed
RESULTS : Of the 50
patients , 32 ( 64 % ) were found to have persistent
glucose dysregulation . -
pubmed
Preoperative FPG levels correlated better with 2 - hour OGTT results than did the 6 - week postoperative FPG values , but both were insensitive markers for diagnosing
type 2 DM in these
patients . -
pubmed
Our data support the need for performing a postoperative OGTT in
patients with no known history of
DM but the presence of
hyperglycemia after a cardiac operation . -
pubmed
Eight
patients sustained a combination of clival epidural
hematoma ,
traumatic sixth cranial nerve palsy ( 6
NP ) , and
occipitocervical injury . -
pubmed
Aberrant atrioventricular conduction in a
patient with
paroxysmal tachycardia , a short P - R interval and a normal QRS complex . -
pubmed
Early globus pallidus internus stimulation in pediatric
patients with generalized
primary dystonia : long - term efficacy and safety . -
pubmed
Except for mild
dysarthria in 2
patients , no other therapy - related morbidity was observed . -
pubmed
The authors found globus pallidus internus stimulation to offer a very effective and safe therapy in pediatric
patients with
primary dystonia . -
pubmed
Challenging pacemaker implantation in a
patient with acquired
dextrocardia after pneumonectomy ,
skoliosis and complete
heart block . -
pubmed
The authors report the case of a pacemaker implantation in a
patient with complete
heart block ,
impaired left ventricular function ,
sclerosis of heart valves and radiation induced
vasculopathy resulting in ostial
stenosis of the right coronary artery 30 years after radiochemotherapy in childhood . -
pubmed
(
Rutaceae ) as potential treatment for
Alzheimer disease . -
pubmed
Furthermore , a better understanding of the
neuropsychological impairments in drug abusing
individuals could help to explain the remitting course of
substance abuse disorders and to improve psychological interventions . -
pubmed
The antitumor activity of
sorafenib alone ( 60 mg / kg ) twice daily ,
cytarabine alone ( 6.25 mg / kg administered intraperitoneally ) , or
sorafenib once or twice daily plus
cytarabine was evaluated in
NOD - SCID - IL2Rgamma ( null ) mice bearing
AML xenografts . -
pubmed
Physical activity coaching of
patients with
rheumatoid arthritis in everyday practice : a long - term follow - up . -
pubmed
CHROMagar KPC appears applicable for processing
carbapenem - resistant Enterobacteriaceae surveillance specimens , but its performance might possibly be suboptimal in the presence of KPC - negative
ertapenem - resistant
strains or for detection of KPC - producing
E. - pubmed
PURPOSE : To evaluate the effects of total body irradiation (
TBI ) on the endocrine system in
adults treated with hematopoietic cell transplantation ( HCT ) during childhood . -
pubmed
METHODS : We studied 40
patients who underwent HCT between 1988 and 2004 , mainly for childhood
cancer . -
pubmed
In 23
patients , the conditioning regimen consisted of high - dose chemotherapy and
TBI (
TBI+ ) . -
pubmed
In the other 17
patients , who did not receive
TBI (
TBI- ) , HCT was performed after high - dose chemotherapy alone . -
pubmed
RESULTS : Overall , 34 % of
patients in the
TBI+ group showed
growth hormone deficiency , compared with none of the
patients in the
TBI- group ( P & lt ; 0.05 ) . -
pubmed
Leydig cell failure was found in 23 % of
patients in the
TBI+ group and in 0 % of the
patients in the
TBI- group . -
pubmed
Also , primary
hypothyroidism was more common in
TBI+ ( 34 % ) than in
TBI- ( 5.8 % )
patients ( P & lt ; 0.05 ) . -
pubmed
CONCLUSIONS : Our data indicate that endocrine late effects after HCT are more frequent in
patients who received
TBI , an observation that should be considered , even if the choice of the conditioning regimen is determined by the underlying condition in most cases . -
pubmed
Coupled experiment / finite element analysis on the mechanical response of
porcine brain under high
strain rates . -
pubmed
This paper presents a coupled experimental / modeling study of the mechanical response of
porcine brain under high
strain rate loading conditions . -
pubmed
Diabetic retinopathy (
DR ) can cause irreversible
blindness and is the severest microvascular complication in the eyes of
patients with
diabetic mellitus (
DM ) . -
pubmed
The identification of susceptibility factors contributing to development of
DR is helpful for identifying predisposed
patients and improving treatment efficacy . -
pubmed
However , due to the high prevalence and poor outcome of
visual pathway impairment , it is important to initiate multiple disciplinary co - operative study on VRT and other procedures for visual function rehabilitation to improve life quality of
patients with retro - chiasmal
visual pathway impairment . -
pubmed
CONCLUSION : Hepatic resection for NETHM provides symptomatic benefit and is associated with favourable survival outcomes although the majority of
patients invariably develop
disease progression . -
pubmed
Seventy - four
patients with
HD were evaluated for cognitive , motor , psychiatric , and functional status using a standardized battery ( Unified
Huntington ' s Disease Rating Scale [ UHDRS ] and supplemental neuropsychological testing ) during a research clinic visit . -
pubmed
[ Clinical study on prevention efficacy of Jianpi Huatan Fang in treating
non - alcoholic fatty liver disease in
children ] . -
pubmed
OBJECTIVE : To verify the clinical efficacy of Jianpi Huatan Fang in treating
non - alcoholic fatty liver disease in
children . -
pubmed
METHOD : Sixty
children patients with
non - alcoholic liver disease were randomly assigned to 2 groups of 30
patients each , being treated with Jianpi Huatan Fang and the
Vitamin E Recipe with a span of 3 months , respectively . -
pubmed
China has seen a massive resurgence of
rabies cases in the last 15 years with more than 25,000
human fatalities . -
pubmed
We also identified epidemiological linkages between high incidence provinces consistent with observations based on surveillance data from
human rabies cases . -
pubmed
METHODS AND RESULTS : Nine typically developing
children ( TD ) and nine
children with
ASDs participated in this study ( Experiment 1 ) . -
pubmed
However , there was no evidence of familiarity effect in
children with
ASDs . -
pubmed
Screening for early detection of
breast cancer : overdiagnosis versus suboptimal
patient management . -
pubmed
Consistent with these results , microscopic observations revealed that
infection of
AGS cells with
H. - pubmed
pylori Deltafur mutant
strain produced much less damage as compared to that produced by the wild - type
H. - pubmed
The variability of the sexual incompatibility genes of
Agrocybe aegerita was investigated in the homokaryotic progeny of 13 wild dikaryotic
strains from five distinct European geographic origins . -
pubmed
A 67 - year - old
man who underwent severe
chronic diarrhea had typical clinical manifestations of
hyperpigmentation ,
hair loss , and
dystrophic changes in the fingernails . -
pubmed
Helicobacter pylori and
anemia with pregnancy . -
pubmed
SUBJECTS AND METHODS : Study was conducted in Ain Shams University hospitals on 100 pregnant
women with
iron - deficiency anemia (
IDA ) , including 50 cases infected with
Helicobacter pylori (
H. - pubmed
CONCLUSION : Response to
iron therapy in cases of
iron deficiency anemia in
patients without
H. - pubmed
Relapse rates ( RRs ) for each
patient group were compared using adjusted negative binomial regression . -
pubmed
It has been estimated that in 2010 there were 4.7 million
individuals aged 65 years or older with
AD dementia , and it is projected that the total number of individuals with
AD dementia in 2050 will be 13.8 million . -
pubmed
We aimed to evaluate the prevalence of
thyroid nodules , the changes in size , volume and number of nodules during pregnancy and after delivery in pregnant
women . -
pubmed
All
patients with
thyroid nodules & gt;1 cm underwent fine - needle aspiration biopsy ( FNAB ) after the last visit at the PP . -
pubmed
A 17 - year - old
patient with
type III Gaucher disease was hospitalized for recurrent
syncope . -
pubmed
Gaucher disease should be kept in mind in the differential diagnosis of a young
patient with extensive vascular and
valvular calcification . -
pubmed
Patients with symptomatic severe
valvular disease must be referred for early surgery . -
pubmed
Adolescents with
eating disorders (
ED ) are at risk of developing
osteoporosis if weight is not recovered . -
pubmed
There have been no controlled trials studying the early use of percutaneous LVADs ( pLVADs ) in
pericardiac arrest patients or intra - arrest as a bridge to return of spontaneous circulation . -
pubmed
The ( 1,3)-beta - D - glucan ( BDG ) test was positive among 94.6 % ( 35/37 ) of candidal
CRBSI patients and 9.4 % ( 10/106 ) of non - candidal
CRBSI cases . -
pubmed
PARTICIPANTS :
Patients ( N=2130 ) enrolled between October 2008 and September 2011 and admitted for inpatient rehabilitation after an index
TBI injury . -
pubmed
METHODS : A cohort of 57
patients with
prostate cancer scanned with
( 68 ) Ga - PSMA-11 PET / CT for radiotherapy planning was retrospectively reviewed ; 15
patients were at initial diagnosis and 42
patients at time of biochemical
recurrence . -
pubmed
Effect of spent turmeric on kidney glycoconjugates in
streptozotocin - induced
diabetic rats . -
pubmed
BACKGROUND :
Curcumin known to have number of medicinal use and masked the fiber containing
ukonan like active polysaccharide in
turmeric and its pharmacological effect will be addressed on
diabetic nephropathy particularly the glycoconjugates of extracellular components viz . -
pubmed
RESULTS : In the present study spent turmeric ( 10 % ) fed
diabetic rats showed improved
glomerular filtration rate ( 50 % ) ,
kidney enlargement ( 60 % ) and other glycoconjugate metabolism in kidney . -
pubmed
The
patients with
MTBI and 40 orthopedic controls ( i.e. -
pubmed
Patients with
MTBI reported more
post - concussion symptoms and
fatigue than the controls at the beginning of recovery , but by 6 months after
injury , did not differ as a group from
nonhead injury trauma controls on cognition ,
fatigue , or mental health , and by 12 months , their level of post -
concussion symptoms and quality of life was similar to that of controls . -
pubmed
Investigation of mucus obtained from different fish species on the acute
pain induced with scalpel incision in paw of
rats . -
pubmed
Atrial fibrillation is the most common
arrhythmia in
thyrotoxicosis , occurring in 5 - 15 % of
patients over 60 years of age , whereas
ventricular arrhythmia is an unusual manifestation . -
pubmed
CASE REPORT : An 18 - year - old Japanese
woman was admitted to our emergency department because of
loss of consciousness caused by
ventricular fibrillation . -
pubmed
AIMS : We sought to evaluate the feasibility and efficacy of hybrid transapical closure of paravalvar mitral leaks using a new Occlutech PLD occluder in
patients with
heart failure and/or
haemolytic anaemia . -
pubmed
Clinical improvement in either
heart failure or
haemolysis was seen in all discharged
patients . -
pubmed
This strategy emphasizes the use of analogous tests and measures in both preclinical and clinical studies , while de - emphasizing the use of preclinical
animal models that attempt to replicate features of the
neuropsychiatric disorder through experimental manipulations . -
pubmed
EXPERT OPINION : Investigating the neurobiology of key psychophysiological processes in
rodents should enhance our understanding of the pathophysiology of
neuropsychiatric disorders . -
pubmed
No such studies are reported in the blood circulation of
patients with essential
hypertension . -
pubmed
MATERIALS AND METHODS : We recruited 132
patients with
essential hypertension and 132 normal controls from similar socio - economic - geographical background . -
pubmed
INTRODUCTION : The purpose of the present study was to evaluate learning curves and short - term outcomes following laparoscopic surgery for early
endometrial cancer in
women of different
body mass index ( BMI ) classes . -
pubmed
MATERIAL AND METHODS : Data from 227
women planned for laparoscopic surgery for presumed stage I
endometrial cancer were collected retrospectively from a Danish gynecologic oncology unit . -
pubmed
AIMS : Stress response , in terms of activation of stress factors , is known to cause
obesity and
coronary heart disease such as
atherosclerosis in
human . -
pubmed
The results indicate that
TiO2 /
PSi thin film irradiated with a single near - infrared wavelength of 808 nm , which is known to have the best
human permeability , offers the potential of being the most successful photothermal
cancer therapy agent . -
pubmed
In this study , to contribute to the improvement of methods for predicting the
butanol - producing ability of
Clostridium beijerinckii based on starch substrate , we further investigate a simple , visualization screening method for selecting target
strains from mutant library of
Clostridium beijerinckii NCIMB 8052 by using
trypan blue dye as an indicator in solid starch via statistical survey and validation of fermentation experiment with controlling pH. -
pubmed
This study compared the outcomes of surgical treatments including bypass surgery , cutting balloon angioplasty and conventional balloon angioplasty to
TA patients exhibiting supra - aortic arterial (
SAA ) . -
pubmed
METHODS : This retrospective study was conducted on 42
TA patients , obtained from hospital database , who underwent surgical therapy due to
SAA lesions from January 2010 to March 2015 . -
pubmed
Although for many patients the mainstay of treatment for early
Charcot ' s neuroarthropathy is conservative care with off - loading , early surgical correction that includes external fixation followed by definitive arthrodesis for select
patients may be warranted . -
pubmed
Protective Effects of
Cucurbitacin B on
Acute Lung Injury Induced by
Sepsis in
Rats . -
pubmed
BACKGROUND The aim of this study was to investigate the protective effects of
cucurbitacin B (
CuB ) on
sepsis - induced
acute lung injury (
ALI ) in
rats . -
pubmed
Soybean presents exciting adjunctive therapies and shows protective benefits for
IC . -
pubmed
Isoflavones are the main bioactive components of
soybean and may be protective against
heart disease . -
pubmed
All
patients with
ischemic stroke were randomly and evenly assigned to two groups : the
isoflavone group ( 80 mg day-1 , n = 100 ) and control group ( 80 mg day-1 placebo , n = 100 ) , and the whole period of the experiment was 24 weeks . -
pubmed
PATIENTS AND METHODS :
Patients with
choroidal nevi were imaged with both OCTA and a fundus photography device . -
pubmed
RESULTS : Fourteen
patients with
choroidal nevi were included . -
pubmed
Histomorphometric study of the anterior latissimus dorsi muscle and evaluation of enzymatic markers of
broilers affected with
dorsal cranial myopathy . -
pubmed
Dorsal cranial myopathy (
DCM ) , which affects the anterior latissimus dorsi ( ALD ) muscles of commercial
broilers , is of unknown etiology , and it represents up to 6 % of the partial condemnations in Brazilian slaughterhouses . -
pubmed
For each age , twelve macroscopically normal
animals and twelve
animals found to exhibit
DCM were randomly selected for histomorphometric evaluation and analysis of serologic profiles . -
pubmed
In addition , it is related to
DCM lesions in fast - growing
broilers with the greatest slaughter weights . -
pubmed
Evaluation of the efficacy and safety of
beta - d - mannuronic acid in
patients with
ankylosing spondylitis : A 12 - week randomized , placebo - controlled , phase I / II clinical trial . -
pubmed
Patients who had
AS according to the modified New York criteria , with active disease at baseline were eligible for study . -
pubmed
Case presentation : An 81 - year - old Morrocan
man , smoker for 40 years , presented with a 1 year history of
dysphonia ,
dyspnea and
dysphagia . -
pubmed
A Missed Opportunity in Bone Health :
Vitamin D and
Calcium Use in Elderly
Femoral Neck Fracture Patients Following Arthroplasty . -
pubmed
Methods : HEALTH is a multicenter randomized trial of elderly
hip fracture patients treated with hemi - arthroplasty and total hip arthroplasty . -
pubmed
Sonographic diagnosis of proximal
median nerve entrapment due to an arteriovenous graft in a hemodialysis
patient . -
pubmed
Besides the well - known palliative effects in
cancer patients ,
cannabinoids have been shown to inhibit in vitro growth of
tumor cells . -
pubmed
PATIENTS AND METHODS : Material and methods : Case studies of the 38 - yerar - old
patient after having operated a big
aneurism of the left ICA , which was clipped . -
pubmed
Conclusion :
Dashansanskar churana and Khadiradi vati showed better results than
chlorhexidine and were found to be superior in managing mild - to - moderate cases of
chronic periodontitis . -
pubmed
To investigate the phosphorylation pattern of protein on
rigor mortis ,
goat longissimus thoracis and external intercostals were classified into two groups ( high quality and low quality ) , and meat quality was evaluated according to meat quality attributes ( Warner - Bratzler shear force , Color , pH and drip loss ) . -
pubmed
This study provides a comprehensive view for the phosphorylation status of
caprine muscle at
rigor mortis , it also gives a better understanding of the regulation of protein phosphorylation on various biological processes that affect the final meat quality attributes . -
pubmed
Materials and Methods : We design a before and after clinical trial study ( registry number : IRCT2012072610405N1 ) and investigated 40
patients with
tennis elbow disease . -
pubmed
All
patients received 2000
pulses extracorporeal
shock wave by piezoelectric device ( WOLF Company ) daily for one - week . -
pubmed
Conclusion : For newly diagnosed
patients with
tennis elbow , extracorporeal
shock wave therapy can reduce the severity of
pain and improve daily activity . -
pubmed
Here we report an unexpected diagnosis of a giant preperitoneal
fibrolipoma detected intraoperatively during laparoscopic cholecystectomy in a 56 - year - old
woman . -
pubmed
[ Screening of mitochondrial DNA damage repair genes in
rats with
septic acute kidney injury ] . -
pubmed
OBJECTIVE : : To screen genes involved in mitochondrial DNA ( mtDNA ) damage repair in
rats with
septic acute kidney injury (
SAKI ) . -
pubmed
The
SAKI mouse model was established by cecal ligation and puncture . -
pubmed
Coronary blood flow volume change is negatively associated with platelet aggregability in
patients with non - obstructive
ischemic heart disease who have no anti - platelet agents . -
pubmed
Therefore , in this study , we investigated the relationship between them in non - obstructive
ischemic heart disease (
IHD )
patients . -
pubmed
METHODS : Three hundred sixty - eight consecutive stable
patients with suspected
angina presenting non - obstructive coronary arteries ( & lt;50 % diameter ) in coronary angiography were investigated with the intracoronary
acetylcholine provocation test and measured
adenosine triphosphate - induced coronary flow reserve . -
pubmed
Furthermore , multivariable linear regression analysis indicated that an incremental CBFV change was independently associated with PRU ( beta = 0.63 , P & lt ; 0.001 ) in non - obstructive
IHD patients . -
pubmed
CONCLUSIONS : In
patients with non - obstructive
IHD , CBFV change was significantly associated with platelet aggregability , indicating that
coronary endothelial dysfunction might mediate higher platelet aggregability . -
pubmed
As we learn about the various molecular alterations in this disease , additional emerging therapies can be developed to improve clinical outcomes in
patients with
mCRC . -
pubmed
Despite a lack of direct comparative data , evidence for potential differences in effectiveness and tolerability within the
dibenzazepine family has emerged from studies in which
patients being treated with one
dibenzazepine agent have received adjunctive treatment with another ( having achieved insufficient
seizure control with the first ) or have transitioned from one
dibenzazepine agent to another because of lack of effectiveness or poor tolerability . -
pubmed
ESL has been shown to be effective as adjunctive therapy in
patients who have previously achieved inadequate
seizure control with
CBZ , indicating that the use of different
dibenzazepine agents in combination can provide additive effectiveness benefits , which may reflect underlying differences in their mechanisms of action . -
pubmed
Aberrant Intrinsic Brain Activity in
Patients with
Autism Spectrum Disorder : Insights from EEG Microstates . -
pubmed
The aim of this study was to examine whether the resting - state EEG microstate analysis could provide novel insights into the abnormal temporal and spatial properties of intrinsic brain activities in
patients with
ASD . -
pubmed
To achieve this goal , EEG microstate analysis was conducted on the resting - state EEG datasets of 15
patients with
ASD and 18 healthy controls from the Healthy Brain Network . -
pubmed
Previous studies indicate that miR-149 could both inhibit and promote the development of
human cancer depending on the
tumor type . -
pubmed
In the United States , outbreaks of
avian influenza H5 and H7 virus infections in poultry have raised concern about the risk for
infections in
humans . -
pubmed
We reviewed the data collected during 2014 - 2017 and found no
human infections among 4,555 exposed responders who were wearing protection . -
pubmed
Effects of
concussion on the blood - brain barrier in
humans and rodents . -
pubmed
Attention is focused on
concussion and
traumatic brain injury in
humans , with a goal of pointing out the gaps in our knowledge and how studies of
rodent model systems of
concussion may help in filling these gaps . -
pubmed
PATIENT CONCERNS : We reported an
HCC patient who developed lung
metastases 1 year after
HCC resection . -
pubmed
DIAGNOSES :
HCC patient with lung
metastases , and pulmonary portal , and mediastinal lymph node
metastases ( stage IVB ) . -
pubmed
Fifteen months after initiation of
brivanib alaninate , the
patient remained in very good condition without evidence of
disease progression . -
pubmed
LESSONS :
Brivanib alaninate alone as second - line therapy showed excellent antitumor efficacy for an
HCC patient with numerous lung and lymph node
metastases . -
pubmed
The objective of this study was to use published information on environmental factors favorable for
infection and historical climate data for the Pacific Northwest to analyze the environmental risk for Karnal bunt to occur if wheat fields in the Pacific Northwest become contaminated by
T. - pubmed
METHODS AND ANALYSIS : The theory - based cluster randomised controlled trial tests an intervention comprising two components : ( 1 ) a theatre workshop for all
children in years 7 and 8 , and ( 2 ) self - management workshops for children with
asthma . -
pubmed
Leukocyte Derived Microvesicles as Disease Progression Biomarkers in Slow Progressing
Amyotrophic Lateral Sclerosis Patients . -
pubmed
The lack of biomarkers in
Amyotrophic Lateral Sclerosis (
ALS ) makes it difficult to determine the stage of the disease in
patients and , therefore , it delays therapeutic trials . -
pubmed
We investigated whether plasma derived microvesicles could be overrepresented in a group of 40
patients affected by
ALS compared to 28
Alzheimer ' s Disease (
AD )
patients and 36 healthy volunteers . -
pubmed
Leukocyte derived MVs ( LMVs ) compared to endothelial , platelet , erythrocyte derived MVs , were mostly present in
ALS patients compared to
AD patients and healthy donors . -
pubmed
Our preliminary findings suggest that LMVs are upregulated in
ALS patients and they can be considered possible markers of
disease progression . -
pubmed
In this work the thermal resistance of different yeasts
strains ( seven belonging to the species
Saccharomyces cerevisiae and six belonging to the species
Kluyveromyces marxianus ,
Zygosaccharomyces bisporus ,
Z. - pubmed
The most resistant
strain , belonging to the species
S. - pubmed
Cellular immune responses in amniotic fluid of
women with
preterm labor and
intra - amniotic infection or
intra - amniotic inflammation . -
pubmed
These findings provide insights into the intra - amniotic immune mechanisms underlying the
human syndrome of
preterm labor . -
pubmed
5
children suffered from bilateral
conductive hearing loss (
CHL ) , 6
children with unilateral
CHL and 6
children with unilateral
sensorineural hearing loss . -
pubmed
Its expression was induced by
SGIV infection in vitro . -
pubmed
The case reported here describes a
woman who underwent a total thyroidectomy for
multinodular goiter and who presented an enlarged lymph node on the left side of the neck , which showed a
metastasis from
PTC . -
pubmed
Fifteen
patients were followed up for 6 to 24 months and exhibited good nasal shape , repaired
alveolar cleft , improved labial shape , and closed
oronasal fistula . -
pubmed
One
patient had local
infection , which was cured by antibiotics . -
pubmed
METHODS : Chart review was done for 619
patients who presented to our institution 's ED with non -
febrile renal colic and received a radiological diagnosis of
ureteral stone of less than 10 mm . -
pubmed
We tested samples collected from
camels ,
camel workers , and other animals in Sudan and Qatar in 2015 and 2017 for evidence of
Middle East respiratory syndrome coronavirus ( MERS - CoV ) infection . -
pubmed
MERS - CoV antibodies were abundant in Sudan camels , but we found no evidence of
MERS - CoV infection in camel workers , other livestock , or bats . -
pubmed
The NEC - protective effects of
human breast milk and its constituent milk
oligosaccharides ( HMOs ) on necroptosis were assessed in a " NEC - in - a - dish " model , in which
mouse intestinal organoids were cultured as either " Undifferentiated " or " Differentiated " epithelium in the presence of NEC - bacteria and
hypoxia . -
pubmed
Strikingly , the addition of
human breast milk or the HMO 2
fucosyllactose in the ex vivo system reduced necroptosis and
inflammation . -
pubmed
RESULTS : Routine consumption of
caffeine ( odds ratio [ OR ] = 3.1 , 95 % CI : 1.23 - 6.41 , P = 0.013 ) ,
tobacco ( OR = 1.8 , 95 % CI : 0.67 - 3.57 , P = 0.03 ) , and
alcohol ( OR = 3.6 , 95 % CI : 0.84 - 7.18 , P = 0.048 ) , and
depression history ( OR = 2.8 , 95 % CI : 0.76- 5.79 , P = 0.037 ) were substantially more common among patients with
bulimia . -
pubmed
The area
strain was the best predictor of LVEF / NYHA improvement in those
patients . -
pubmed
METHODS : A multicenter retrospective descriptive study was conducted in 19 dermatology departments , including all
patients with
PPP or
ACH seen from 2014 to 2016 who received one of the studied biologics . -
pubmed
The cultivated
potato is susceptible and lacks resistance to bacterial wilt ( BW ) , a
soil - borne disease caused by
Ralstonia solanacearum . -
pubmed
The limited hemocompatibility of currently used oxygenator membranes prevents long - term use of artificial lungs in
patients with
lung failure . -
pubmed
INTRODUCTION :
acrylamide is formed in food through Maillard 's reaction during thermal processing , and has been shown to be
neurotoxic in
humans , and a possible carcinogen . -
pubmed
Preferential inhibition of adaptive immune system dynamics by glucocorticoids in
patients after
acute surgical trauma . -
pubmed
Resting - state EEG Connectivity in Young
Children with
ADHD . -
pubmed
METHOD : We collected EEG data in 52 medication - naive
children with
ADHD and in 77 typically developing controls ( 3 - 7 years ) . -
pubmed
While
mammals tend to repair
injuries , other adult
vertebrates like
salamanders and fish regenerate damaged tissue . -
pubmed
We assessed their impact on short- and long - term outcome in
patients with
colorectal liver metastases who underwent 2 - stage liver resections . -
pubmed
Patients with high intramuscular fat before the second hepatectomy also showed shorter intervals from
recurrence to treatment failure . -
pubmed
The Sustained Attention to Response Task ( SART ) was administered to 120
children with
ADHD and 123 controls on three occasions between ages 9 and 14 . -
pubmed
We describe the cases of two
children who presented with severe
abdominal pain ,
non - bilious vomiting and high temperatures during the UK 's first peak of the COVID-19 pandemic . -
pubmed
Clinically , the majority of
patients presented with nonspecific symptoms of
cough ,
chest pain , and
dyspnea . -
pubmed
Diagnostic imaging showed the presence of an anterior mediastinal mass and surgical resection of the
tumor mass was performed in all the
patients . -
pubmed
Overweight /
obesity were lower among men ( OR : 0.45 , 95 % CI : 0.340 to 0.593 , p<=0.001 ) and among patients aged > = 65 years ( OR : 0.52 , 95 % CI : 0.350 to 0.770 , p=0.001 ) ; patients who rarely ate
fruits and vegetables ( OR : 0.66 , 95 % CI : 0.475 to 0.921 , p=0.014 ) but higher among patients of middle ( OR : 1.83 , 95 % CI : 1.320 to 2.550 , p<=0.001 ) and upper ( OR : 2.10 , 95 % CI : 1.450 to 2.990 , p<=0.001 ) socioeconomic status ; on dual therapy ( OR : 2.17 , 95 % CI : 1.024 to 4.604 , p=0.043 ) ; with
peripheral neuropathy ( OR : 1.40 , 95 % CI : 1.039 to 1.834 , p=0.026 ) and
hypertension ( OR : 1.70 , 95 % CI : 1.264 to 2.293 , p<=0.001 ) . -
pubmed
Rhodiola sacra ( Prain ex Hamet ) S. H. Fu is a traditional natural plant pharmaceutical with anti -
hypoxia effect and mainly distributed in Yunnan and Tibet ( China ) . -
pubmed
To reveal the features of the effect of low - intensity microwave EMR / UHF on the development of adaptive metabolic and ultrastructural changes in the liver and blood of
rats at an early stage of
MS development . -
pubmed
The derivative toxins purified from cultures of proteolytic
strains of
Clostridium botulinum types A and F were found to have been only partially nicked but were fully activated . -
pubmed
Macrophage function in
tumor - bearing
mice : tumoricidal and chemotactic responses of macrophages activated by
infection with
Mycobacterium bovis , strain BCG . -
pubmed
Thirty - one
patients who had undergone a bilateral tympanic neurectomy ( sectioning of both Jacobson 's nerve and the chorda tympani ) for
sialorrhea are evaluated after two years ( ranging from 24 - -45 months ) . -
pubmed
Effect of pelleted feed on the incidence of
gizzard erosion and black
vomit in
broilers . -
pubmed
We evaluated the effect of breathing 100 ppm of
carbon monoxide versus compressed , purified air for 1 hour on exercise performance in 10
patients with
chronic obstructive pulmonary disease in a double - blind , randomized , crossover study . -
pubmed
Breathing 100 ppm of
carbon monoxide for 1 hour caused a significant reduction in exercise performance in
patients with
chronic obstructive pulmonary disease . -
pubmed
Six months after surgery the
patient was well and no further
haemorrhage had occured . -
pubmed
Ten
patients with
tubal infertility without antisperm antibodies or
endometriosis served as controls . -
pubmed
A retrospective review was made of roentgenograms from 30
patients with
idiopathic osteoarthrosis of the hip . -
pubmed
Natural killer ( NK ) cell activity was measured in nine
patients with different
solid tumors treated with
flavone acetic acid (
FAA ) . -
pubmed
This study investigates the quality of life of
patients on alternative therapies for
end - stage renal disease . -
pubmed
Different effects of
epoprostenol on
ischemia - induced
ventricular arrhythmias in
dogs . -
pubmed
In 60 randomized
dogs the effects of
epoprostenol infusion ( 100 ng / kg / min ) on
ischemia - induced
premature ventricular contractions ( PVCs ) ,
ventricular tachycardia (
VT ) ,
ventricular flutters and
ventricular fibrillation were studied . -
pubmed
The circumflex
coronary artery occlusion canine model of
sudden death was used . -
pubmed
The results demonstrate different effects of
epoprostenol on
ischemia - induced
ventricular arrhythmias : 1 ) both postischemic ( 7 of 30 vs 15 of 30 , p = 0.0298 ) and postreperfusion ( 5 of 23 vs 8 of 15 , p = 0.0492 )
ventricular fibrillations were prevented in
epoprostenol dogs with an improvement of the global survival rate ( 18 of 30 vs 7 of 30 , p = 0.0019 ) as compared to controls ; 2 ) in
epoprostenol treated
dogs a significantly increased incidence of non lethal
arrhythmias - including
ventricular flutters that occurred in 12 of 30
dogs vs 4 of 30 in controls ( p = 0.0195)--was observed ; 3 ) a positive correlation between the percent diastolic pressure fall 10 min after the start of
epoprostenol infusion and the number of non lethal
arrhythmias was noted . -
pubmed
Thus , the antifibrillatory and antiarrhythmic effects of
epoprostenol after circumflex
coronary artery occlusion and reperfusion in
dogs seem independent from one another . -
pubmed
The incidence of
nephrotoxicity in
patients receiving
vancomycin alone or in combination with an
aminoglycoside was prospectively evaluated . -
pubmed
Eight
patients ( 5 % ) receiving
vancomycin alone , 14 patients ( 22 % ) receiving
vancomycin with an
aminoglycoside , and 11 patients ( 11 % ) receiving
gentamicin alone were found to have
nephrotoxicity . -
pubmed
Factors found to be associated with increased risk of
nephrotoxicity in
patients receiving
vancomycin were concurrent therapy with an
aminoglycoside , length of treatment with
vancomycin ( greater than 21 days ) , and
vancomycin trough serum concentration ( greater than 10 mg / l ) . -
pubmed
Twenty - three of 1006 ( 2.3 % )
uveal melanoma patients treated with proton beam therapy at the Harvard Cyclotron Laboratory between July 1975 and December 31 , 1986 received additional treatment for documented ( 15
patients ) or suspected ( eight
patients )
tumor growth in the irradiated eye . -
pubmed
Documented growth occurred in nine of 665 ( 1.4 % )
patients with small and intermediate size
tumors , at times after treatment ranging from 6 to 48 months ( median 16 months ) , and in three of 341 ( .9 % )
patients with large
tumors at 7 , 11 , and 12 months after treatment . -
pubmed
Melanoma growing totally outside the treated volume was also documented in three additional
patients at 7 , 9 , and 45 months ; two of these were thought to be " ring
melanomas " . -
pubmed
Eight
patients had the treated eye removed elsewhere for suspected
tumor growth . -
pubmed
Based on these data , it appears that a dose of 70 CGE in five fractions is associated with very high rates of local control in
human uveal melanoma . -
pubmed
Gastrospirillum hominis infection of the stomach . -
pubmed
Mutagenicity profiles of newer
amsacrine analogues with activity against
solid tumours : comparison of
microbial and mammalian systems . -
pubmed
The objective of this study was to evaluate the effect of gland cottonseed dietary fiber ( CSDF ) containing 86 % dietary fiber ( mainly cellulose ) on serum
glucose levels in
diabetic rats and in
non - insulin - dependent diabetes mellitus (
NIDDM )
patients . -
pubmed
A diet containing 15 % CSDF given to
streptozotocin - induced
diabetic rats for 30 d tended to reduce the postprandial plasma
glucose level curve . -
pubmed
Twelve
NIDDM subjects were given a meal tolerance test ( MTT ) with or without CSDF before and after daily supplementation of CSDF ( 16.5 g ) in
pita twice a day for a month . -
pubmed
Low plasma lipid levels and increased
cholesterol synthesis after partial ileal bypass plus
lovastatin in
hypercholesterolemic rabbits . -
pubmed
For 14 weeks , 32
New Zealand White rabbits received a C - free ,
alfalfa - free , natural - ingredients diet previously shown to induce
hypercholesterolemia . -
pubmed
[
Hemorrhagic proctitis in male homosexuals caused by
Chlamydia trachomatis ] . -
pubmed
Viral - related RNA in
Hodgkins ' disease and other
human lymphomas . -
pubmed
Molecular hybridization with radioactively labeled DNA complementary to the RNA of the
Rauscher leukemia virus was used to probe for homologous RNA in
human lymphomas . -
pubmed
22 of 32 specimens contained RNA possessing homology to the RNA of the
mouse leukemia virus , but not to that of the unrelated viruses causing
mammary tumors in
mice or
myeloblastosis in
chickens . -
pubmed
It appears that
human lymphomas contain RNA sequences homologous to those found in a viral agent known to cause
leukemia and
lymphomas in an experimental animal . -
pubmed
The fact that
human leukemias and
sarcomas also contain this type of RNA further emphasizes a remarkable similarity between the corresponding
neoplasias of
murine and
human origin . -
pubmed
A case of
megaloblastic anemia in the
gibbon (
Hylobates foolock ) . -
pubmed
[ On the therapy of
peripheral circulatory disorders with the new angioactivator
Tebonin of
plant origin ] . -
pubmed
Transient
aplastic crisis in
children with
congenital hemolytic anemias has been linked epidemiologically to
infection with a serum parvovirus - like virus (
SPLV ) . -
pubmed
The case histories of 519
patients with
peripheral neuropathy on whom sural nerve biopsy had been performed were reviewed . -
pubmed
In 67
patients ( 50
males , 17
females ) ( 13 % ) who had symptoms of a symmetrical
polyneuropathy for more than one year , the cause remained undiagnosed in spite of intensive investigation . -
pubmed
Patients with
inflammatory neuropathy were not included , but represented 17 % of the whole series . -
pubmed
The clinical features in 43
patients were those of a mixed
motor and sensory neuropathy , in 17
patients a predominantly
sensory neuropathy and in 7
patients a predominantly
motor neuropathy . -
pubmed
A possible aetiological factor was found in 17 of the 47
patients ( 36 % ) and included
malignancy ,
alcoholism , and benign
paraproteinaemia . -
pubmed
It is concluded that with intensive investigation the cause of chronic
polyneuropathy of duration greater than one year remains undetermined in only about 13 % of
patients and that continued follow - up is worthwhile since a diagnosis may be established on re - examination . -
pubmed
Male
cats that were fed the
EFA - deficient diet for approximately 2 years exhibited extensive
degeneration of the testes , and the
fatty acid composition of testes changed in a manner consistent with
EFA deficiency . -
pubmed
The regimen resulted in complete
azoospermia or severe
oligozoospermia in all the
animals within 75 days of treatment accompanied with decreased motility , vitality and increased sperm abnormalities . -
pubmed
Upper urinary tract deterioration in
patients with
myelodysplasia and
detrusor hypertonia : a followup study . -
pubmed
We report on 6
patients with
myelodysplasia who had undergone previously urodynamic evaluation that demonstrated
detrusor hypertonia . -
pubmed
Subsequently ,
upper urinary tract deterioration and/or
vesicoureteral reflux developed in all
patients and persisting
detrusor hypertonia was demonstrated on followup urodynamic testing . -
pubmed
Our experience indicates that
detrusor hypertonia can lead to ureteral complications in
patients with previously radiographically normal upper urinary tracts . -
pubmed
OBJECTIVES : To examine the relationship between maternal
HIV infection ,
placental malaria infection , and infant mortality as a first step in investigating the possibility of increased vertical transmission of
HIV due to
placental malaria infection . -
pubmed
If confirmed ,
malaria chemoprophylaxis during pregnancy could decrease the impact of transmission of
HIV from mother to infant . -
pubmed
Although the newest compounds exhibit good activity against
Streptococcus pneumoniae and intracellular pathogens in animal models , the role of
quinolones as first line therapy in community - acquired
pneumonia is still debatable and may be modified according to clinical presentation and the rate of resistance of pneumococci to
beta - lactams and macrolides . -
pubmed
Intra - arterial infusion chemotherapy via an implantable port catheter has been applied in 16
patients with locally recurrent
breast cancer . -
pubmed
Murine retrovirus - induced depletion of T cells is mediated through activation - induced
death by apoptosis . -
pubmed
Here we show for the first time that a
murine retrovirus which also induces
immunodeficiency can cause apoptotic T - cell
death . -
pubmed
Relationships between plasma levels of
catecholamines and neuropeptides and the survival time in
patients with
congestive heart failure . -
pubmed
OBJECTIVES : To evaluate the importance of various variables reflecting neuroendocrine activation in relation to prognosis in
patients with
congestive heart failure (
CHF ) . -
pubmed
SUBJECTS : Thirty - one
patients with
CHF due to
ischaemic heart disease . -
pubmed
One hundred twenty pediatric
patients with
acute watery diarrhea ( 60 in each group ) were studied , but only 116
patients were included in the final analysis . -
pubmed
We describe two
children with
deficiency of short - chain L-3 - hydroxyacyl - CoA dehydrogenase , a new disorder of the mitochondrial beta - oxidation of straight - chain
fatty acids . -
pubmed
The
patients presented with fasting - induced
vomiting , and
ketosis and low blood
glucose , features typical of
ketotic hypoglycemia were documented in one . -
pubmed
A 45 - year - old
man with the acute form of
pyoderma gangrenosum is reported . -
pubmed
Nineteen
patients were considered high risk : six had previous cardiac surgery , three were on chronic dialysis , two required emergency surgery for
low output syndrome , one had a chronic tracheotomy for
chronic lung disease , and seven had left ventricular ejection fraction & lt ; 30 % . -
pubmed
MR consisted of ring application alone in 28
patients ,
chordal shortening in nine , posterior leaflet transfer in six and posterior leaflet resection in four . -
pubmed
PATIENTS : The study cohort comprised 30
patients who presented with a profile of suspicion for
nonorganic hearing loss . -
pubmed
In order to assess the impact of a control program against
Triatoma infestans launched in 1988 , based on insecticide spraying of dwellings , a serological survey for
chagasic infection was carried out during 1995 in three localities from San Pedro de Atacama County ( 22 degrees 55 ' South lat . -
pubmed
Blood samples from 531 children and adolescents and 65
dogs were subjected to ELISA test and indirect immunofluorescent test for
Chagas ' disease respectively . -
pubmed
infestans is a good tool to prevent new
human infections with
T. - pubmed
RESULTS : A diagnosis of
herpes simplex encephalitis was confirmed in 42
patients . -
pubmed
Three
patients ( 7 % ) had severe
neurological sequelae and died after a longer interval . -
pubmed
Twenty
patients ( 48 % ) performed everyday activities as well as before
herpes simplex encephalitis ; nine patients ( 21 % ) were living independently , but were functioning at a lower level than before the illness ; and five
patients ( 12 % ) had a severe
neurological deficit . -
pubmed
A 37 - year - old
woman with
chronic renal failure developed
pain in the right flank during haemodialysis followed by rapid and dramatic deepening of pigmentation . -
pubmed
Lightheadedness and
unsteadiness were prominent symptoms in the elderly
patients . -
pubmed
Since
patients with surgical resection of & gt ; 3 kg remained
anemic at 10 weeks , oral
iron supplements could benefit this subset of patients . -
pubmed
METHODS : A total of 33
HIV-1 - infected patients with and without
neurological disorders were included in the study . -
pubmed
Phase II study of
estramustine and
vinorelbine in
hormone - refractory prostate carcinoma patients . -
pubmed
The purpose of this study was to evaluate the antitumor activity of
vinorelbine and oral
estramustine phosphate in
patients with
metastatic , hormone - refractory prostate cancer . -
pubmed
Anemia was observed in 5
patients ,
alopecia in 4 and
nausea and
vomiting was observed in 6
patients . -
pubmed
Anorexia and
weight loss of more than 10 % were observed in 2
patients . -
pubmed
Lung transplant
recipients could particularly benefit from this enhanced exposure , but not at the expense of excessive
cyclosporine toxicity . -
pubmed
Nine
patients with
cystic fibrosis (
CF ) were randomly selected independently ( 5 , Neoral ; 4 ,
Sandimmune ) . -
pubmed
However ,
patients with
CF required 2 to 3 times the dose of both
Neoral and
Sandimmune to achieve the same C0 as non - CF
patients . -
pubmed
Mice receiving these bone - resorbing factors became
hypercalcemic by day 3 after commencing treatment and had increased
bone resorption as evidenced by elevated osteoclast numbers on day 5 . -
pubmed
We aim to evaluate the use of the easier performable trocar technique in draining
critically ill patients with acute calculous or acalculous
cholecystitis . -
pubmed
PATIENTS AND METHODS :
Critically ill patients with acute acalculous (
AAC ; n=29 ) or
calculous cholecystitis (
ACC ; n=7 ) underwent trocar technique application of USD . -
pubmed
Estrogen , the drug of choice in perimenopausal
women , is generally not recommenced to
breast cancer survivors . -
pubmed
PATIENTS AND METHODS : Thirty
women with prior
breast cancer who were suffering at least two
hot flashes a day entered a single institution pilot trial to evaluate
paroxetine 's efficacy in reducing the frequency and severity of
hot flashes . -
pubmed
The most common adverse effect was
somnolence , resulting in drug discontinuation in two
women , and dose reduction in two
women . -
pubmed
One
woman discontinued drug due to
anxiety . -
pubmed
Ablation of this gene in
mice leads to
death shortly after birth , and abnormalities have been found in both the peripheral and central nervous systems . -
pubmed
Differential scanning calorimetry , biochemical , and biomechanical analysis of
human skin from individuals with
diabetes mellitus . -
pubmed
HB2 antibody treatment of
SCID - HSB-2 mice also led to a significant prolongation in time to
leukaemia development compared with sham - treated controls with 37 % of animals in this treatment group disease - free at termination of the study . -
pubmed
Desmopressin in a long - term treatment of
children with
primary nocturnal enuresis -- a symptomatic therapy ? -
pubmed
Enrolled in the present study were 58
patients with acute
glomerulonephritis , 58 with
chronic glomerulonephritis and 16 controls . -
pubmed
The third and fourth sounds were detected in 61
patient with
glomerulonephritis . -
pubmed
It is well known that the 5 - year survival rate of advanced
ovarian cancer patients greatly improved after the appearance of
cisplatin . -
pubmed
We examined the outcome and
adverse drug reactions in 102
ovarian cancer patients who underwent repeated intraperitoneal administration of
cisplatin in our hospital between April 1987 and April 1999 . -
pubmed
Records of 24 consecutive
patients having permanent mesh placement in contaminated
wounds for repair of
abdominal wall hernias between 1994 and 2001 were reviewed . -
pubmed
Placement of permanent mesh prostheses in clean - contaminated and contaminated operative fields can be performed with minimal
wound - related morbidity and
patient mortality . -
pubmed
Smoke - induced
lung injury in
rats was assessed in terms of histopathology , gross mortality , neutrophil accumulation and as capillary leak . -
pubmed
Lupus myelopathy in a
child . -
pubmed
BACKGROUND :
Calcium absorption is generally considered to be impaired under conditions of
vitamin D deficiency , but the
vitamin D status that fully normalizes absorption is not known for
humans . -
pubmed
Does
coinfection with
Human Herpesvirus 6 have a protective effect for
HIV-1 progression ? -
pubmed
In contrast ,
papilloma formation in
Tg . - pubmed
AIMS : The present study was initiated by a very recent histochemical observation of lipid accumulation in the renal cortex of a
woman who died in a
diabetic coma . -
pubmed
Two older reports of lipid accumulation in the kidneys of
patients who died , most likely in a state of non - regulated
diabetes , supported this observation . -
pubmed
Ten
subjects who died in a
diabetic coma , eight
diabetics who died of known causes unrelated to
diabetes , and seven normal control subjects without any diagnosed
diabetes who died of known causes . -
pubmed
Detailed analysis of cortex lipids was performed for two of the
subjects who died in a
diabetic coma and all
diabetic controls as well as non - diabetic control subjects . -
pubmed
RESULTS : All
subjects who died in a
diabetic coma showed
vacuolar lesions staining strongly for lipid in the proximal tubules . -
pubmed
Compared with normal controls , renal cortex lipid was about tripled in the two analysed
diabetic coma subjects due to 60 - 100 - fold increases of
triglycerides . -
pubmed
Dogs with a history of Gorilla Glue ingestion should be monitored closely by their owners and a veterinary referral made if signs of
gastrointestinal distress develop . -
pubmed
Parenteral feeding in a
patient with
hypertriglyceridemia and increased liver enzyme levels . -
pubmed
OBJECTIVE : To discuss nutritional support in a
patient with
hypertriglyceridemia and
liver dysfunction . -
pubmed
METHODS : We describe the hospital course of a
critically ill patient with
hepatic dysfunction and
hypertriglyceridemia who required nutritional support , and we provide an overview of lipid metabolism . -
pubmed
RESULTS : A 27 - year - old
man with
hepatic dysfunction and
hypertriglyceridemia , who had undergone kidney transplantation 4 months previously , was admitted to the intensive - care unit with
upper gastrointestinal bleeding . -
pubmed
CONCLUSION : Nutritional support in
patients with
liver dysfunction and
hypertriglyceridemia is complicated and may require temporary underfeeding because of the need to limit fat and
dextrose intake . -
pubmed
We treated a 26 - year - old
man with a 19 - year history of
Ollier ' s disease . -
pubmed
This is the first report of multiple bilateral metachronous malignant transformation of multiple
chondromatoses in a
patient with
Ollier ' s disease . -
pubmed
One important objective is to prevent
human cancer . -
pubmed
The aim of this study was to correlate the severity of
retinopathy in
diabetic patients with red blood aggregation and some parameters of aggregation . -
pubmed
The study was carried out on 52
patients suffering from
type 2 diabetes mellitus with
non - proliferative retinopathy--25
men and 27
women ( mean age 63.8 + /- 6.5 years ) and 43 healthy--20
men and 23
women ( mean age 55.5 + /- 9.6 years ) . -
pubmed
The fundus appearance of
patients showed non - proliferative
diabetic retinopathy . -
pubmed
Once - weekly
fluconazole in
children with
tinea capitis due to
Microsporum canis . -
pubmed
OBJECTIVE : To systematically assess dream characteristics and
daytime aggressiveness in
patients with
RBD and controls . -
pubmed
METHODS : Forty - nine
patients with polysomnographic - confirmed
RBD diagnosis and 71 age- and sex - matched controls were asked to recall the most recent dreams and to complete the Aggression Questionnaire ( AQ ) . -
pubmed
Forty - one
patients with
RBD ( 81.6 % ; 36
men , 5
women ; mean age : 67.5 + /- 7.5 years ) and 35 controls ( 49.3 % ; 30
men , 5
women ; mean age : 69.1 + /- 5.9 years ) were able to remember their dreams and a total of 98 ( RBD ) and 69 ( controls ) dreams were collected in the two groups . -
pubmed
RESULTS :
Patients with
RBD showed a higher percentage of dream with at least one
aggressive episode ( DWA ) than controls ( 66 % vs 15 % ; p & lt ; 0.00001 ) , a higher
aggression / friendliness interaction ratio ( 86 % vs 44 % ; p & lt ; 0.0001 ) , and a greater frequency of animal characters ( 19 % vs 4 % ; p = 0.0001 ) . -
pubmed
CONCLUSIONS : Dreams in
patients with
REM sleep behavior disorder were characterized by an elevated proportion of aggressive contents , despite normal levels of
daytime aggressiveness . -
pubmed
Quantitative EEG analysis in
dexamphetamine - responsive
adults with
attention - deficit / hyperactivity disorder . -
pubmed
Attention - deficit / hyperactivity disorder (
AD /
HD ) is recognized as a disorder affecting
children and
adolescents and has more recently been documented to continue into adulthood in a proportion of
patients . -
pubmed
Numerous studies have examined the therapeutic effects of stimulant medications in
children ,
adolescents and
adults with the disorder , reporting improvements in attention , concentration , and
hyperactive and impulsive behaviours . -
pubmed
Several studies have also examined the effects of stimulants on the electroencephalograph ( EEG ) of
children and
adolescents with the disorder , but to date , there have been no studies examining the effects of stimulant medication on the EEG of
adults with
AD /
HD . -
pubmed
In the present study , we aimed to replicate previous EEG findings in
adults with
AD /
HD relative to controls and to examine whether there was any change in this profile following treatment with
dexamphetamine . -
pubmed
The pre - medication results are similar to those found in previous research that compared the EEGs of
adults with
AD /
HD and control subjects . -
pubmed
Over the past decade ,
adenovirus (
Ad)-based vectors have been used extensively in the context of
cancer gene therapy . -
pubmed
Several obstacles limiting the therapeutic activity of
Ad vectors have been encountered , including efficiency of
tumor cell transduction and inhibition of efficacy by anti - Ad host immune responses . -
pubmed
Involvement of
adenosine in
depression of synaptic transmission during
hypercapnia in isolated spinal cord of neonatal
rats . -
pubmed
In the isolated spinal cord of the neonatal
rat in vitro , acute hypercapnic
acidosis ( 20 %
CO2 , pH 6.7 ) reversibly depressed electrically evoked spinal reflex potentials . -
pubmed
MATERIAL AND METHODS : Two hundred and four
patients of
non - traumatic myelopathy were prospectively studied in different wards of Sir Sundar Lal Hospital , Institute of Medical Sciences , Banaras Hindu University , Varanasi , from September 2002 to March2004 . -
pubmed
RESULTS : Among 204
patients of
non - traumatic myelopathy , 108
patients presented with
paraplegia and 96
patients with
quadriplegia . -
pubmed
Patient - controlled analgesia in the management of
postoperative pain . -
pubmed
Patient - controlled analgesia ( PCA ) is a delivery system with which
patients self - administer predetermined doses of analgesic medication to relieve their
pain . -
pubmed
These include improved
pain relief , greater
patient satisfaction , less sedation and fewer
postoperative complications . -
pubmed
Susceptibility of
CCR5 - deficient mice to
genital herpes simplex virus type 2 is linked to NK cell mobilization . -
pubmed
Unfortunately ,
ACC has undergone metastatic spread in 40 % to 70 % of
patients at the time of diagnosis . -
pubmed
Genomes of 25
ACC clinical samples were queried on the Agilent 44 K
Human Genome comparative genomic hybridization array detecting regions of chromosomal gain and loss within the
tumor population . -
pubmed
Inhibition of
influenza A H3N8 virus infections in
mice by
morpholino oligomers . -
pubmed
Monitoring of
body weight and immune cell infiltrates in the lungs of noninfected
mice indicated that
PPMO treatment was not toxic at a concentration shown to be effectively antiviral in vivo . -
pubmed
METHOD : Measures completed included the Children 's
Depression Inventory , the Multidimensional Anxiety Scale for
Children , the Child Behavior Checklist and the Disruptive Behavior Rating Scale . -
pubmed
Lateral sinus thrombosis is a rare complication of
middle ear diseases : in
children , it is usually related to
acute otitis media , but it is also found in adults with chronic
otitis . -
pubmed
Hypericum perforatum ( St John 's wort ) for
attention - deficit / hyperactivity disorder in children and adolescents : a randomized controlled trial . -
pubmed
CONTEXT : Stimulant medication can effectively treat 60 % to 70 % of
youth with
attention - deficit / hyperactivity disorder (
ADHD ) . -
pubmed
perforatum for the treatment of
ADHD in
children . -
pubmed
DESIGN , SETTING , AND PARTICIPANTS : Randomized , double - blind , placebo - controlled trial conducted between March 2005 and August 2006 at Bastyr University , Kenmore , Washington , among a volunteer sample of 54
children aged 6 to 17 years who met Diagnostic and Statistical Manual of
Mental Disorders ( Fourth Edition ) criteria for
ADHD by structured interview . -
pubmed
perforatum vs 3.2 points ( 95 % CI , -5.7 to -0.8 points ) with placebo ( P = .68 ) and
hyperactivity improved 1.8 points ( 95 % CI , -3.7 to 0.1 points ) with
H. - pubmed
Therapeutic time window and mechanism of
tetramethylpyrazine on transient focal
cerebral ischemia /
reperfusion injury in
rats . -
pubmed
Middle cerebral artery occlusion was conducted in male
Sprague - Dawley rats and 20mg / kg
tetramethylpyrazine was injected intraperitoneally at different time points . -
pubmed
Controversy surrounds the optimal technique for fixation of displaced
fractures , although locked intramedullary nailing is emerging as a preferred technique in managing displaced
proximal humerus fractures in appropriately selected
patients . -
pubmed
OBJECTIVE : To isolate and elucidate the chemical constituents with the
cytotoxicity activity from the rhizome of
Actaea asiatica . -
pubmed
In this investigation 830 healthy controls , 69
subjects with
cognitive impairment and not
dementia (
CIND ) , 53
patients with severe clinical
AD and 142
patients with
mild AD were investigated . -
pubmed
Patients with mild clinical
AD were followed up for two years and stratified according to the rate of
clinical deterioration . -
pubmed
Clinical outcomes after platelet transfusions in
patients with
thrombotic thrombocytopenic purpura . -
pubmed
STUDY DESIGN AND METHODS : Published reports of PLT transfusions in
patients with
TTP were systematically reviewed and data from the Oklahoma TTP - HUS Registry , an inception cohort of 382 consecutive
patients , 1989 through 2007 , were analyzed . -
pubmed
The frequency of
death was not different between the two groups ( p = 0.971 ): 8 ( 24 % )
patients who received PLT transfusions died (
thrombosis , 5 ;
hemorrhage , 1 ;
sepsis , 2 ) and 5 ( 24 % ) patients who did not receive PLT transfusions died (
thrombosis , 4 ;
hemorrhage , 1 ) . -
pubmed
CONCLUSION : Evidence for harm from PLT transfusions in
patients with
TTP is uncertain . -
pubmed
Vandetanib versus
gefitinib in
patients with advanced
non - small - cell lung cancer : results from a two - part , double - blind , randomized phase ii study . -
pubmed
Risk factors for
recurrence after
Staphylococcus aureus bacteraemia . -
pubmed
OBJECTIVES : We sought to identify risk factors for
recurrence of
Staphylococcus aureus bacteraemia (
SAB ) by auditing compliance with guidelines on its treatment in our hospital . -
pubmed
Analysis of outcomes of vascularized flap reconstruction in
patients with advanced
mandibular osteoradionecrosis . -
pubmed
SUBJECTS :
Patients with end - stage radiation - induced
osteoradionecrosis (
ORN ) refractory to conservative therapy with
wound complications including
chronic infections ,
fistula formation , and pathologic
fracture were included . -
pubmed
An elusive
tumor in a
man who has evidence of
prostate cancer metastasis . -
pubmed
Attenuation of
allergy to ovomucoid in
pigs by neonatal treatment with heat - killed
Escherichia coli or
E. - pubmed
To assess induction of
allergy ,
pigs were fed egg white in yoghurt and assigned scores for
allergic signs . -
pubmed
Significantly fewer
pigs developed
allergy and passive cutaneous
anaphylaxis in
E. - pubmed
Seventy nonobese
patients with
CHC ( Group 1 ) confirmed by the presence of serum
hepatitis C virus (
HCV)-RNA and 20 healthy volunteers ( Group 2 ) , similar in age and
BMI with normal fasting
glucose and lipid profile were included . -
pubmed
The lowest levels were found in
patients with the most advanced
inflammation : grades 3 - 4 - 46.8 + /- 17.1 , grade 2 - 52.6 + /- 18.4 and grade 1 - 75.2 + /- 27.6 ng / mL ; P = 0.017 . -
pubmed
Regarding " Prediction of 30 - day mortality after endovascular repair or open surgery in
patients with ruptured
abdominal aortic aneurysms " . -
pubmed
BACKGROUND AND PURPOSE : Low - dose lipopolysaccharide ( LPS ) preconditioning provides neonatal
rats long - term neuroprotection against
hypoxic ischemia (
HI ) . -
pubmed
CASE PRESENTATION : A 73 - year - old Caucasian
woman presented to our department with sudden onset , severe , left - upper
abdominal pain . -
pubmed
Postictal delta can be lateralized in 60 % of
patients with
TLE and is concordant with the side of
seizure onset in most
patients . -
pubmed
Accurate localization of the
seizure onset in these
patients is required for successful surgical management . -
pubmed
Midterm results of arterial switch operation in older
patients with severe
pulmonary hypertension . -
pubmed
BACKGROUND : It is widely accepted that
patients older than 6 months with dextrotransposition of the great arteries and nonrestrictive
ventricular septal defect or
Taussig - Bing anomaly and severe
pulmonary hypertension usually are not candidates for an arterial switch operation or even repair . -
pubmed
METHODS : The records of 86
patients older than 6 months with dextrotransposition of the great arteries and nonrestrictive
ventricular septal defect or
Taussig - Bing anomaly and severe
pulmonary hypertension undergoing the arterial switch operation at our institution from 2000 to 2008 were reviewed retrospectively . -
pubmed
CONCLUSIONS : Midterm results of the arterial switch operation for
patients older than 6 months with dextrotransposition of the great arteries and nonrestrictive
ventricular septal defect or
Taussig - Bing anomaly and severe
pulmonary hypertension are excellent in the current era . -
pubmed
We show for the first time that
dehydration leads to an increase in cellular PtdIns5P in
Arabidopsis . -
pubmed
[ Clinical characteristics of
hepatic veno - occlusive disease in 6
children with
hematologic neoplasm treated with
6 - thioguanine ] . -
pubmed
OBJECTIVE : To improve the treatment of drug related childhood
hepatic veno - occlusive disease (
HVOD ) , clinical characteristics of 6
children with
hematologic neoplasm from 2 hospitals of China
Children 's
Leukemia Group ( CCLG ) treated with
6 - thioguanine (
6 - TG ) complicated with
HVOD were analyzed . -
pubmed
METHOD : All the drug related
HVOD patients were treated with CCLG
acute lymphoblastic leukemia (
ALL)-2008 protocol . -
pubmed
The 6
HVOD patients ' clinical manifestations , laboratory finding , imageologic and pathologic data were collected and analyzed . -
pubmed
All the
patients recovered after being treated with hepatoprotective ,
jaundice - relieving and supportive therapeutics , some
patients were treated with low molecular weight
heparin . -
pubmed
Mortality associated with
atrial fibrillation in
patients with
myocardial infarction : a systematic review and meta - analysis . -
pubmed
BACKGROUND :
Atrial fibrillation (
AF ) is a common finding in
patients with
myocardial infarction (
MI ) . -
pubmed
Drugs administered individually or as a mixtures of all three after
TBI significantly increased
mouse survival ( p = 0.0234 , 0.0009 , 0.0052 , and 0.0167 , respectively ) . -
pubmed
CONCLUSION : Mitochondrial targeting of small molecule radiation mitigators decreases irradiation - induced cell
death in vitro and prolongs survival of lethally irradiated
mice . -
pubmed
Two
patients experienced
hematoma and one
patient experienced late
infection at four months postoperatively . -
pubmed
These data provide surgeons with a less invasive treatment option for
patients with early
breast cancer , even when they have undergone prior breast augmentation through a transaxillary approach . -
pubmed
METHODS : This prospective study included adult
patients with progressive
LGG that was confirmed by magnetic resonance imaging ( MRI ) . -
pubmed
RESULTS : A total of 21
LGGs from 31
patients were included in the study , and followed for at least n=14 months during treatment . -
pubmed
A total of 18 ( 86 % )
patients experienced a decrease in
tumour volume with a greater decrease of metabolic ratios . -
pubmed
The evolutions over time of metabolic ratios , mean(
Cho /
Cr)(n ) and mean(
Cho /
NAA)(n ) , were significantly correlated with the evolution of the mean relative decrease of
tumour volume , mean(DeltaV(n)/V(o ) ) , according to a linear regression ( P<0.001 ) in the ' response / no
relapse '
patient group , and with the evolution of the mean
tumour volume ( meanV(n ) ) , according to an exponential regression ( P<0.001 ) in the ' response /
relapse '
patient group . -
pubmed
Incidence and diagnosis of
heparin - induced
thrombocytopenia (
HIT ) in
patients with
traumatic injuries treated with
unfractioned or low - molecular - weight heparin : a literature review . -
pubmed
CONCLUSION : The incidence of
HIT in
trauma patients who receive
LMWH thromboprophylaxis appears to be low ( 0.36 % ) . -
pubmed
Incidence of
HIT in
patients with isolated lower
leg injuries receiving
LMWH seems very low . -
pubmed
Monitoring of platelet count could be considered in hospitalised
patients with a high risk for development of
HIT . -
pubmed
Using
bacterial artificial chromosome technology , each of these mutations was individually transferred into the genome of a reference
strain . -
pubmed
ewingii have been thought to cause
ehrlichiosis in
humans in the United States . -
pubmed
RESULTS : On testing , four cases of
ehrlichiosis in Minnesota or Wisconsin were found not to be from
E. - pubmed
A total of 108
rats were randomly distributed into three groups : sham - operated group ( n = 12 ) ,
middle cerebral artery occlusion (
MCAO ) group ( n = 48 ) , MCAO+treadmill exercise group ( n = 48 ) . -
pubmed
Behavioral testing indicated that treadmill exercise could significantly improve
neurologic deficits of
rats with
cerebral ischemia at day 14 and 28 after
MCAO ( n = 12 , P<0.05 and P<0.01 ) , but there was no significant difference at day 4 and 7 . -
pubmed
Administered as monotherapy or in combination with other antihyperglycemic agents , they represented an effective option for achieving or maintaining good glycemic control in
patients with
T2DM . -
pubmed
Seroma was seen in 8.6 % ( 5 ) of
patients . -
pubmed
CONCLUSIONS :
EE 20 mcg / drsp 3 mg in a 21/7 - day regimen provides comparable
ovarian suppression in Japanese and Caucasian
women , with normal ovarian function resuming shortly after treatment end in both populations . -
pubmed
BACKGROUND & amp ; AIMS : Parenteral nutrition is widely used in
critically ill patients receiving nutritional support . -
pubmed
Statistical analysis of data , grouped according to preparation method , compared differences in both observed
bloodstream infection rates and adjusted rates , using logistic regression to examine the impact of hospital and
patient baseline characteristics . -
pubmed
Vegetal polymer in repair of
defects of the orbital floor : an experimental study in
rabbits . -
pubmed
We extracted the following information : author names and publication year ; clinical outcome ( number of
deaths and Glasgow outcome scales ) ; perioperative data ( number of moderate or severe intraoperative
brain swelling occurrences ,
hypertensive episodes , ruptured or leaking
aneurysms , volume of
blood loss during surgery , duration of temporary clipping , and number of
patients who received protective drugs , who required rewarming and who were intubated ) ; number of adverse events (
cerebral infarctions ,
brain swelling ,
myocardial ischaemia or
infarction ,
congestive heart failure ,
meningitis or
ventriculitis and
pneumonia ) . -
pubmed
RESULTS : The number of
patients requiring rewarming in the mild
hypothermia group was significantly greater than in the normothermia group ( odds ratio , 33.89 ; 95 % confidence intervals , 3.61 - 318.36 ) . -
pubmed
PATIENTS :
Patients undergoing total hip replacement , total knee replacement , or
hip fracture surgery who received prophylaxis with a
LMWH or another anticoagulant . -
pubmed
Patients with idiopathic passive
faecal incontinence were selected for trans - submucosal injection of Permacol ( ) after assessment by anorectal physiology and endoanal ultrasonography . -
pubmed
Compounds 1 - 7 were tested in vitro for their
cytotoxic effects on five cell lines including
human gastric
adenocarcinoma cell line (
BGC823 ) ,
human hepatocarcinoma cell line (
HepG2 ) ,
human melanoma cell line (
A375 ) ,
human oral
squamous carcinoma cell line (
KB ) , and ghost cell line (
Ghost - R5X4 ) . -
pubmed
Cost - effectiveness of adding - on new antiepileptic drugs to conventional regimens in controlling intractable
seizures in
children . -
pubmed
0.06 % of
children around the world are estimated to suffer from
epilepsy and its consequences . -
pubmed
The aim of the present study has been to evaluate the cost - effectiveness of these drugs in the treatment of intractable
seizures in
children . -
pubmed
With the advent of deep sequencing , efforts have been put forth to profile the miRNome in a number of
human malignancies . -
pubmed
We describe a new technique to prevent spillage of
cyst fluid in
patients undergoing surgery for
cystic ovarian tumors . -
pubmed
DESIGN AND METHODS : Thirteen postpartum
women ( mean + - SD : 25.6 + - 4.5 years , 72.0 + - 11.9 kg ) provided fore- and hindmilk samples 4 - 5 weeks after delivery and underwent measurements of
body weight and composition by Dual X - ray Absorptiometry . -
pubmed
By delivering small - diameter nociceptive - specific laser
pulses to
human volunteers , we discovered that ( 1 ) the spatial acuity for
pain is higher on the fingertips than on proximal skin regions such as the hand dorsum , and ( 2 ) this distal - proximal gradient for
pain is comparable to that for touch . -
pubmed
Identification of novel exons and transcripts by comprehensive RNA - Seq of
horn cancer transcriptome in
Bos indicus . -
pubmed
Horn cancer (
HC ) is a widely prevalent
cancer amongst
Bos indicus cattle and frequently associated with economic losses due to reduction in draught and milk production capacity . -
pubmed
A 74 - year - old male
patient with a newly diagnosed
prostate cancer had whole - body bone scintigraphy for staging . -
pubmed
Many people infected with the
human immunodeficiency virus type-1 (
HIV ) exhibit mild or severe neurological problems , termed
HIV - associated neurocognitive disorder (
HAND ) , even when receiving antiretroviral therapy . -
pubmed
Thus , novel adjunctive therapies must be developed to overcome the
neurotoxic effect of
HIV . -
pubmed
HIV appears to impair neuronal plasticity , which refers to the innate ability of the CNS respond to
injury and promote recovery of function . -
pubmed
OBJECTIVE : To identify risk factors for developing a first
febrile status epilepticus (
FSE ) among
children with a first
febrile seizure (
FS ) . -
pubmed
STUDY DESIGN : Cases were
children with a first FS that was FSE drawn from the Consequences of Prolonged
Febrile Seizures in Childhood and Columbia cohorts . -
pubmed
MATERIALS AND METHODS : Volumetric scans of 247
individuals exposed to
tobacco with different functional status ( normal to severe
COPD ) , were retrospectively and independently evaluated by 2 chest radiologists , with a consensual reading additionally with a third reader in disagreement cases . -
pubmed
OBJECTIVES : There is evidence that
androgens are breast protective and that
testosterone therapy treats many symptoms of
hormone deficiency in both pre and postmenopausal
patients . -
pubmed
However , unlike
estrogen and
progestins , there is a paucity of data regarding the incidence of
breast cancer in
women treated with
testosterone therapy . -
pubmed
This study was designed to investigate the incidence of
breast cancer in
women treated with subcutaneous
testosterone therapy in the absence of systemic
estrogen therapy . -
pubmed
Breast cancer incidence was compared with that of historical controls reported in the literature , age specific Surveillance Epidemiology and End Results ( SEER ) incidence rates , and a representative , similar age group of our
patients used as a ' control ' group . -
pubmed
Differences in proliferative capacity of primary
human acute myelogenous leukaemia cells are associated with altered gene expression profiles and can be used for subclassification of
patients . -
pubmed
OBJECTIVES : Proliferative capacity of
acute myelogenous leukaemia (
AML ) blasts is important for leukaemogenesis , and we have investigated whether proliferative capacity of primary
human AML cells could be used for subclassification of
patients . -
pubmed
CONCLUSIONS : In vitro proliferative capacity of primary
human AML cells was considerably variable between patients and could be used to identify biologically distinct
patient subsets . -
pubmed
During a median follow - up of 41 months , no
patient developed
exocrine insufficiency . -
pubmed
Three elderly
patients developed
non - insulin - dependent diabetes mellitus . -
pubmed
One
patient with
VIPoma developed
recurrence and liver
metastasis . -
pubmed
Surveillance of intra - abdominal pressure and intestinal barrier function in a
rat model of acute necrotizing
pancreatitis and its potential early therapeutic window . -
pubmed
Methanolic extracts of both
Pedicularis sibthorpii and
Pedicularis wilhelmsiana were found to have antibacterial activity especially against gram positive
strains of
S. - pubmed
Clinical data ,
aneurysm characteristics , treatment methods , and the incidence and causes of re - exploration of the craniotomy were analyzed for these 26
patients . -
pubmed
RESULTS : Several causes of re - exploration were identified : compromised distal blood flow ( eight
patients , 0.47 % ) ,
hemorrhagic venous infarction ( four
patients , 0.23 % ) ,
brain retraction injury ( three patients , 0.17 % ) , newly identified
aneurysms ( three patients , 0.17 % ) ,
bleeding from an incompletely clipped
aneurysm ( two patients , 0.12 % ) ,
epidural hematoma ( two
patients , 0.12 % ) , failed
aneurysm clipping ( two patients , 0.12 % ) and other causes ( two
patients , 0.12 % ) . -
pubmed
However , this dosing regimen resulted in average trough concentrations & gt;20 mg / L. In the peritoneal cavity , no regimen yielded
PTA & gt;=90 % for MIC values & gt;=0.5 mg / L. CONCLUSIONS : Although expert guidelines suggest iv
vancomycin may be an acceptable empirical therapy for
patients on APD with
infection , these analyses indicate that iv
vancomycin may not be effective for
peritonitis but may be a viable option for
non - peritoneal infections with MIC values & lt;=1 mg / L. -
pubmed
However , the molecular mechanisms underlying compensatory liver regeneration in
mice after
APAP - induced
liver injury are not completely understood . -
pubmed
We found that
mice exhibited massive
hepatic toxicity during the first 12 hours after 400 mg / kg
APAP treatment , but responsive liver recovery occurred beyond 24 hours as demonstrated by histopathological and biochemical assessments . -
pubmed
[ Soluble apoptosis markers in
obese patients with
food intolerance ] . -
pubmed
For the soluble apoptosis markers study 151
patients with
obesity ( 92
women and 59
men ) aged between 18 and 63 years were examined . -
pubmed
Generally
food intolerance was identified in 36.4 % of obese
patients . -
pubmed
Obese
patients with
food intolerance received standard version of hypocaloric diet with the exception of specific food allergens . -
pubmed
Factors associated with the seroprevalence of
leishmaniasis in
dogs living around Atlantic Forest fragments . -
pubmed
The results showed that different risk factors than those found in urban areas may drive the prevalence of
canine leishmaniasis in farm / forest interfaces , and that
humans and wildlife risk
infection in these areas . -
pubmed
Noncontact , low - frequency ultrasound therapy enhances neovascularization and
wound healing in
diabetic mice . -
pubmed
BACKGROUND :
Chronic wounds are a major source of morbidity for
patients and represent a significant health burden . -
pubmed
Ultrasound appears to be an effective modality for the treatment of
chronic wounds in
humans . -
pubmed
CONCLUSION : Noncontact , low - frequency ultrasound treatment improves neovascularization and wound closure rates in excisional
wounds for
diabetic mice , likely because of the stimulated release of angiogenic factors . -
pubmed
Characterization of circulating microRNA expression in
patients with a
ventricular septal defect . -
pubmed
METHODS : MiRNA microarray analysis and reverse transcription - polymerase chain reaction ( RT - PCR ) were employed to determine the miRNA expression profile from 3
patients with
VSD and 3 VSD - free controls . -
pubmed
miRNAs that were generally consensus across the three databases were selected and then independently validated using real time PCR in plasma samples from 20
VSD patients and 15 VSD - free controls . -
pubmed
RESULTS : 36 differentially expressed miRNAs were found in the
patients with
VSD and the VSD - free controls . -
pubmed
CONCLUSION : We report for the first time the circulating miRNA profile for
patients with
VSD and showed that 7 miRNAs were downregulated and 1 upregulated when matched to VSD - free controls . -
pubmed
Preclinical safety evaluation of a recombinant AAV8 vector for
X - linked retinoschisis after intravitreal administration in
rabbits . -
pubmed
In conclusion , intravitreal administration of AAV8 - scRS / IRBPhRS into the
rabbit eye produces a mild and transient
intraocular inflammation that resolves , at a 2e(10 ) vg / eye dose , within 3 months , and does not cause irreversible tissue damages . -
pubmed
These data support the initiation of a clinical trial of intravitreal administration of AAV8 - scRS / IRBPhRS in
XLRS patients . -
pubmed
We report here the complete genome sequence of a novel reassortant H4N2
avian influenza virus
strain ,
A / duck / Guangxi / 125D17 / 2012 ( H4N2 ) ( GX125D17 ) , isolated from a duck in Guangxi Province , China in 2012 . -
pubmed
Information about the complete genome sequence of the
GX125D17 virus strain will be useful for epidemiological studies . -
pubmed
The acquisition of
genomic instability is a triggering factor in
cancer development , and common fragile sites (
CFS ) are the preferential target of
chromosomal instability under conditions of replicative stress in the
human genome . -
pubmed
TRALI :
human neutrophil antigens and antibodies . -
pubmed
A 74 - year - old
woman was admitted to our department on day two of a bilateral PICA
thrombosis with developing
cerebellar infarction . -
pubmed
Hepatitis B virus (
HBV ) remains a major
human pathogen , with over 240 million individuals suffering from chronic
HBV infections . -
pubmed
Using
lentiviral transduction of a bacterial Cas9 gene and single guide RNAs ( sgRNAs ) specific for
HBV , we observed effective inhibition of
HBV DNA production in in vitro models of both chronic and de novo
HBV infection . -
pubmed
METHODS : Fifty
patients with
myopia who underwent LASIK ( 100 eyes ) were divided into two equal groups . -
pubmed
METHODS : EPSN was measured in 92 sera collected from 46 pregnant
women with birth at term and 40 sera from 20 pregnant
women with
preterm birth . -
pubmed
Patients with
SPB showed a considerable increase of EPSN in the second trimester compared with
patients with birth at term ( 7.30 + -1.53 vs. 6.16 + -0.23 , P=0.043 ) . -
pubmed
After an in vitro model of IR was established by treating
human liver cancer cells (
HepG2 cells ) with
palmitic acid , the cells were then treated with various concentrations of QJJ . -
pubmed
CONCLUSION : The treatment of warm needling combined with element
calcium on postmenopausal
osteoporosis is significant , which is likely to be achieved by reducing the bone metabolism of postmenopausal
patients . -
pubmed
Though both the low concentration of
spinosad and the ultra - low - volume application rate of
GF-120 are supposed to have a low
acute toxicity in
honey bee foragers , to our knowledge such claims have not been explicitly proven . -
pubmed
BACKGROUND : Health promoting schools focus on , amongst other things , preventing leading causes of
death such as
Sexually Transmitted Infections (
STI 's ) ,
Human Immune Deficiency Virus (
HIV ) and
Acquired Immunodeficiency Syndrome (
AIDS ) , a sedentary lifestyle and creating conditions that are conducive to health through health education . -
pubmed
Echinacea Formula ( Echinaforce Hotdrink ): Effects of a Proprietary
Echinacea Formula Compared With
Oseltamivir in the Early Treatment of
Influenza . -
pubmed
Traditionally , in oriental medicine ,
apricot seed ( Semen
Armeniacae amarum ) is used to treat
skin diseases . -
pubmed
PATIENTS : 108
patients with unstable
pelvic injuries were operated by the orthopedic department at the Soroka University Medical Center between the years 1999 - 2010 . -
pubmed
Antibacterial effect of
N - acetylcysteine on common
canine otitis externa isolates . -
pubmed
BACKGROUND :
N - Acetylcysteine (
NAC ) has the potential to be a useful therapeutic agent for the treatment of
otitis externa due to its antimicrobial and mucolytic properties , as well as its ability to disrupt
bacterial biofilm . -
pubmed
ANIMALS : Twenty two isolates from
canine clinical cases of
otitis externa were identified and tested , including five
Staphylococcus pseudintermedius , six
Pseudomonas aeruginosa , five Corynebacterium spp . -
pubmed
CONCLUSIONS AND CLINICAL RELEVANCE :
N - Acetylcysteine inhibits clinically relevant and drug resistant
bacteria in vitro , and has potential for use as a novel agent for treatment of
otitis externa . -
pubmed
METHODS : A retrospective analysis was performed of 98
patients with
TBC who underwent BDC of 2510
patients with
traumatic brain injury . -
pubmed
For the rich mobilome of a hospital
Klebsiella pneumoniae strain , circularization junctions ( CJs ) were detected for six GIs and seven IS types . -
pubmed
Forty diabetic
patients with critical
coronary stenosis were subjected to elective coronary scaffold implantation in Al - Najaf Center for Cardiac Surgery and Trans - Catheter Therapy , Najaf , Iraq , between January and July 2015 . -
pubmed
CONCLUSION : Our study concluded that
trimetazidine minimizes the acute inflammatory response occurred due to systemic release of inflammatory markers into blood in
diabetic patients undergoing elective Novolimus bioresorbable coronary scaffold implementation . -
pubmed
Antimicrobial - resistant
pneumococcal strains have been detected worldwide since the 1960s . -
pubmed
In Brazil , the first
penicillin - nonsusceptible pneumococci ( PNSP ) were reported in the 1980s , and their emergence and dissemination have been mainly attributed to serogroup 9 and
serotype 14 strains , especially those highly related to recognized international clones . -
pubmed
The earliest PNSP
strains detected in this study belonged to
serotype 9N / ST66 and were single locus variants of the international clone Tennessee14 - 18 ST67 ( CC66 ) . -
pubmed
Experimental Design : Early - passage
human malignant mesothelioma cell lines
NCI - Meso16 ,
NCI - Meso19 ,
NCI - Meso21 , and
NCI - Meso29 were evaluated for sensitivity to RG7787 or nab -
paclitaxel alone or in combination . -
pubmed
In addition , the antitumor activity of RG7787 plus nab -
paclitaxel was evaluated using
NCI - Meso16 ,
NCI - Meso21 , and
NCI - Meso29 tumor xenografts in
immunodeficient mice . -
pubmed
These results indicate that this combination could be useful for treating
patients with
mesothelioma . -
pubmed
INTRODUCTION :
Renal cell carcinoma (
RCC ) is the most fatal of the common
urologic cancers , with approximately 35 % of
patients dying within 5 years following diagnosis . -
pubmed
There were no differences in the intervention effect on 90 - day mortality in
patients with
chronic lung disease ( test of interaction P = 0.31 ) ,
haematological malignancy ( P = 0.47 ) , metastatic
cancer ( P = 0.51 ) , in those who had undergone surgery ( P = 0.99 ) or in patients with
septic shock by the new definition ( P = 0.20 ) . -
pubmed
RESULTS : The
patients ' mean age was 63 + - 13 years , 81 % were male , 53 % had an ischemic cause of
heart failure , and 68 % underwent LVAD implantation as destination therapy . -
pubmed
CONCLUSIONS : Continuous - flow LVAD improves renal and hepatic functions in
patients with advanced
heart failure . -
pubmed
BACKGROUND : A study was performed in
adults with
acute appendicitis and matched controls to assess the utility of the platelet indices and neutrophil to lymphocyte ratio , as a diagnostic adjunct . -
pubmed
METHOD : Data were retrospectively collected from a complete blood count test of 155 adult
patients ( 72
men and 83
women ) with histologically proven
acute appendicitis upon admission , and of 50 healthy adults ( 20 men and 30 women ) . -
pubmed
A single older
stroke patient showed baseline ipsilateral MCAV that was lower still and devoid of any exercise response whatsoever . -
pubmed
METHODS : The present prospective cross sectional study was performed on
critically ill patients presented to emergency department during 6 months . -
pubmed
RESULTS : 82
critically ill patients with the mean age of 53.45 + - 20.37 years were included ( 65.9 % male ) . -
pubmed
The purpose of this study is to compare the two methods ' success and practicality that are applied after the
fracture of the stone in the
patients who applied PCNL and which enable the removal of the residual stones . -
pubmed
Feeding
rosemary leaves powder ameliorates rooster age - related
subfertility . -
pubmed
On the basis of the phenotypic and phylogenetic data , along with low dDDH and ANI values among these
strains , these bacteria are assigned to the following nine novel species of the
B. - pubmed
, type
strain Mn5 T (= MCCC 1A00395T = KCTC 33714T = LMG 28873 T ) ;
Bacillus pacificus sp . - pubmed
, type
strain EB422 T (= MCCC 1A06182T = KCTC 33858 T ) ;
Bacillus tropicus sp . - pubmed
, type
strain N24 T (= MCCC 1A01406T = KCTC 33711T = LMG 28874 T ) ;
Bacillus albus sp . - pubmed
, type
strain N35 - 10 - 2 T (= MCCC 1A02146T = KCTC 33710T = LMG 28875 T ) ;
Bacillus mobilis sp . - pubmed
, type
strain 0711P9 - 1 T (= MCCC 1A05942T = KCTC 33717T = LMG 28877 T ) ;
Bacillus luti sp . - pubmed
, type
strain TD41 T (= MCCC 1A00359T = KCTC 33716T = LMG 28872 T ) ;
Bacillus proteolyticus sp . - pubmed
, type
strain TD42 T (= MCCC 1A00365T = KCTC 33715T = LMG 28870 T ) ;
Bacillus nitratireducens sp . - pubmed
, type
strain 4049 T (= MCCC 1A00732T = KCTC 33713T = LMG 28871 T ) ; and
Bacillus paramycoides sp . - pubmed
Test formula was a hypoallergenic , nutritionally complete AAF including a prebiotic blend of fructo - oligosaccharides and the probiotic
strain Bifidobacterium breve M-16V. -
pubmed
Methods : Forty
patients with metastatic castration - resistant
prostate cancer were selected for treatment with three 100 kBq / kg cycles of
225Ac - PSMA-617 at 2 - mo intervals . -
pubmed
Five
patients discontinued treatment because of nonresponse , and 4 because of
xerostomia . -
pubmed
The median duration of
tumor control under
225Ac - PSMA-617 last - line therapy was 9.0 mo ; 5
patients had an enduring response of more than 2 y. -
pubmed
Because all
patients had advanced disease , this result compares favorably with the
tumor control rates associated with earlier - phase disease ; the most common preceding first- , second- , third- , and fourth - line therapies were
abiraterone ( median duration 10.0 mo ) ,
docetaxel ( 6.5 mo ) ,
enzalutamide ( 6.5 mo ) , and
cabazitaxel ( 6.0 mo ) , respectively . -
pubmed
Swimmer - plot analysis indicates a promising duration of
tumor control , especially considering the unfavorable prognostic profile of the selected advanced - stage
patients . -
pubmed
Xerostomia was the main reason
patients discontinued therapy or refused additional administrations and was in the same dimension as nonresponse ; this finding indicates that further modifications of the treatment regimen with regard to side effects might be necessary to further enhance the therapeutic range . -
pubmed
Urinary tract infection due to
Fusarium oxysporum in an immunocompetent patient with
chronic kidney disease . -
pubmed
Fusarium oxysporum has been reported to cause
keratitis ,
onychomycosis ,
skin infections ,
catheter associated fungemia and has not been described as a cause of
urinary tract infection . -
pubmed
vulgare ,
Apiaceae ) is an important plant currently used in folk medicine to treat various diseases including
infections and inflammatory conditions . -
pubmed
OBJECTIVE : The aim of our study was to investigate the potential differential effect of
hyperglycaemia and
hyperinsulinaemia induced by
glucose infusion alone and in combination with
leucine consumption on endothelial function in healthy
individuals . -
pubmed
CONCLUSIONS : Acute
hyperglycaemia impairs endothelial function in healthy
male individuals . -
pubmed
This study reports the case of a 39 - year - old pregnant
woman at 22 weeks of gestation with massive
enlargement of bilateral breasts (
gigantomastia ) and presents the sonographic findings of this rare condition which shows different parenchymal patterns from those of normal breasts and is uncommonly seen . -
pubmed
AIMS :
Acute respiratory distress syndrome (
ARDS ) , one of the serious form of
acute lung injury (
ALI ) , is the primary cause of death in
patients with
ALI . -
pubmed
Therefore , the aim of the present study was to investigate protective effect of SND on
ALI model induced by
E. - pubmed
Helicobacter pylori chronic gastritis updated Sydney grading in relation to endoscopic findings and
H. - pubmed
Helicobacter pylori (
Hp ) inhabits the stomach of & gt ; 50 % of
humans and has been established as a major etiological factor in the pathogenesis of
chronic gastritis ,
gastric atrophy ,
peptic ulcer disease ,
gastric adenocarcinoma , and
gastric mucosa - associated lymphoid tissue lymphoma . -
pubmed
This analytical study was conducted on 157
patients with
dyspeptic gastritis . -
pubmed
Since
Staphylococcus aureus nasopharynx carriage is a known risk factor for
PD infections and the oral cavity is a starting point for
systemic diseases development , we aimed at comparing the oral staphylococci colonization between
PD patients and controls and studying the association with
PD - related infections . -
pubmed
Although all patients presenting
Staphylococcus epidermidis PD - related
infections were also colonized in the oral cavity by the same agent , only 1 out of 7 patients with ESI caused by
S. - pubmed
The association between oral Staphylococcus carriage and
PD - related infections was present for
S. - pubmed
The compound ,
5 - aminolevulinic acid (
5 - ALA ) is approved for fluorescence - guided resections of
malignant gliomas in Europe and other countries for use in
adults , but not for
children . -
pubmed
Benefit - risk profile of
black cohosh ( isopropanolic
Cimicifuga racemosa extract ) with and without St John 's wort in
breast cancer patients . -
pubmed
After
breast cancer , even if receiving
tamoxifen ,
patients using iCR / iCR + HP had significantly increased
recurrence - free survival rates compared to non - users . -
pubmed
A group of 32 healthy young
adults with no history of a
mood disorder ( Mage = 20.8 , SD = 2.1 ) and 62 remitted
depressed young
adults ( Mage = 21.1 , SD = 1.9 ) completed a neuropsychological battery . -
pubmed
No differences were found between healthy controls and remitted
depressed patients in either memory domain ( all ps & gt ; .05 ) and improvement in performance was exhibited over time for both groups ( p = 0.004 ) . -
pubmed
Structural dynamics of
bacteriophage P22 infection initiation revealed by cryo - electron tomography . -
pubmed
We use cryo - electron tomography to study the
infection initiation of phage P22 in
Salmonella enterica serovar Typhimurium , revealing how a channel forms to allow genome translocation into the cytoplasm . -
pubmed
About 70 % of
BC patients will subsequently suffer disease
relapse , manifesting as local , regional , or distant
tumor recurrence , which clearly underscores the urgent need to discover novel
recurrence inhibitors . -
pubmed
Herein we report the novel activity of daily oral treatment with
OC ( 10 mg / kg ) in preventing BC locoregional
recurrence in a
nude mouse xenograft model generated by orthotopic inoculation with
BT-474 cells as a luminal type B model . -
pubmed
Because of concomitant
type 2 diabetes , all
men were treated with
metformin ( 2550 - 3000 mg daily ) . -
pubmed
BACKGROUND : The ketogenic diet ( KD ) has been frequently used for the
patients with
drug - resistant epilepsy in recent years . -
pubmed
Four
patients had upper
gastrointestinal bleeding , and one patient had
hyperammonemic acute hepatic failure while receiving KD . -
pubmed
Of the
patients , 41.9 % had
seizure - related ED admission . -
pubmed
The frequency of
status epilepticus was significantly lower in the
patients who were on the KD for more than 6 months ( p & lt ; 0.01 ) . -
pubmed
METHODS : Sixty - nine
patients with tibial plateau
fractures were examined . -
pubmed
The external fixation group had shorter operation times ( 172.94 + - 50.00 min vs 253.86 + - 64.59 min ) , less
bleeding volume ( 395.88 + - 121.10 mL vs 864.29 + - 238.12 mL ) , and fewer days ( 17.03 + - 5.03 days vs 30.17 + - 8.64 days ) of hospitalization compared to the internal fixation ( t - test , P = 0.00 ) ; subgroup analysis of all
patients with complex tibial plateau
fractures revealed that for
patients with tibial plateau
fracture type VI , the functional score of external fixation ( 26.79 + - 2.04 ) is better than that ( 25.54 + - 1.69 ) of internal fixation ( t- test , P = 0.026 ) and the overall
infection rate of external fixation is lower than that of internal fixation ( chi2 - test , P = 0.047 ) . -
pubmed
METHODS : We performed a retrospective review of
patients at our institution who underwent an extended thymectomy for a
thymoma from 1976 to 2015 . -
pubmed
RESULTS : A total of 194
patients with
thymoma were eligible for this study . -
pubmed
PARTICIPANTS : Two hundred fifty - three eyes of 221
patients with
exudative AMD . -
pubmed
METHODS : Baseline data were collected on all eyes diagnosed with
exudative AMD , which included
ethnic data . -
pubmed
RESULTS :
Exudative AMD was diagnosed in 253 eyes of 221
patients . -
pubmed
Polypoidal choroidal vasculopathy was noted in 51.6 % ( 81/157 ) of eyes with wet
AMD in
Asians , 31.9 % ( 23/72 eyes ) of eyes with wet
AMD in white
persons , and 28.6 % ( 4/14 eyes ) in a small group of Pacific Islanders . -
pubmed
CONCLUSIONS :
Polypoidal choroidal vasculopathy is more prevalent in Asian
patients with
exudative AMD , but is more prevalent than generally recognized in white
patients . -
pubmed
The
patient underwent sigmoidectomy with the primary pathologic diagnosis of
adenocarcinoma . -
pubmed
In the
patients with
gastrointestinal malakoplakia , the presence of possible adjacent
malignancy should be screened . -
pubmed
BACKGROUND : Women with
human immunodeficiency virus (
HIV ) have higher rates of abnormal cervical and vaginal cytology and , subsequently , of
cervical and vaginal cancers . -
pubmed
METHODS : For this study ,
patients with comorbid
TMD and systemic / neurologic conditions were compared using clinical diagnostic markers , inflammatory ,
pain , tissue destruction enzymatic biomarkers , and functional magnetic resonance imaging ( fMRI ) activity of the brain , with and without a custom - made dental orthotic . -
pubmed
There was a marked elevation of biomarkers in samples taken from TMJ of
patients who were clinically diagnosed with
TMD . -
pubmed
The fMRI study of
TMD patients showed an abnormal hyper - connected salience network and a diminished blood flow to the anterior frontal lobes when they did not wear their customized dental orthotics . -
pubmed
MRgFUS Pallidothalamic Tractotomy for Chronic Therapy - Resistant
Parkinson ' s Disease in 51 Consecutive
Patients : Single Center Experience . -
pubmed
Background : There is a long history , beginning in the 1940s , of ablative neurosurgery on the pallidal efferent fibers to treat
patients suffering from
Parkinson ' s disease (
PD ) . -
pubmed
Patients reported an 88 % mean
tremor relief and 82 % mean global symptom relief on the operated side and 69 % mean global symptom improvement for the whole body . -
pubmed
Conclusion : MRgFUS PTT was shown to be a safe and effective intervention for
PD patients , addressing all symptoms , with varying effectiveness . -
pubmed
Chemoradiotherapy and radiotherapy alone in
patients with
esophageal cancer aged 80 years or older based on the Comprehensive Registry of
Esophageal Cancer in Japan . -
pubmed
The purpose of the present study was to evaluate the results of radiotherapy and chemoradiotherapy in
patients aged 80 years or older with
esophageal cancer in the Japanese Nationwide Cancer Database . -
pubmed
METHODS : A total of 358
patients aged 80 years or older who were treated with radiotherapy alone or with chemoradiotherapy for
esophageal cancer between 2009 and 2011 were enrolled . -
pubmed
In multivariate analysis , chemoradiotherapy , early stage and
squamous cell carcinoma were significantly favorable prognostic factors for OS in
patients aged 80 years or older ( p & lt ; 0.001 , p & lt ; 0.001 and p = 0.0323 , respectively ) . -
pubmed
CONCLUSION : Concurrent chemotherapy with radiotherapy for
esophageal cancer in
patients aged 80 years or older is a significantly favorable prognostic factor for OS . -
pubmed
Nicotine , the main component of
tobacco , is reportedly associated with the development and
rupture of
AAA . -
pubmed
IS VAGINAL DELIVERY HARMFUL TO
PATIENTS WITH
PSEUDOXANTHOMA ELASTICUM ? -
pubmed
BACKGROUND / PURPOSE : To investigate the effect of a vaginal delivery ( VD ) on retinal pathology in
patients with
pseudoxanthoma elasticum . -
pubmed
All 14 consecutive
women with
pseudoxanthoma elasticum who visited the ophthalmology department during pregnancy and after delivery between 2010 and 2018 were included . -
pubmed
RESULTS : Fourteen
patients ( 15 deliveries ) were included , of whom 11
patients ( 79 % ) had a
VD and three
patients ( 21 % ) a secondary caesarian section . -
pubmed
Data of three
patients with
VD ( four deliveries ) could not be assessed for ( sub)
retinal hemorrhage within 10 weeks postpartum . -
pubmed
All
patients had
angioid streaks in the central 5,500 microm of the posterior pole of both eyes . -
pubmed
After delivery , no
patient in the VD or caesarian section group presented with progression of
angioid streaks or ( sub)
retinal hemorrhage . -
pubmed
CONCLUSION : Pushing during the expulsion phase of VD seems safe in
pseudoxanthoma elasticum patients without active
choroidal neovascularization , and the presence of
angioid streaks alone should not be an indication for elective caesarian section . -
pubmed
Update on the Treatment of
Medullary Thyroid Carcinoma in
Patients with
Multiple Endocrine Neoplasia Type 2 . -
pubmed
Effects of Combined Bushen Zhichan Recipe and
Levodopa in a
Rodent Model of
Parkinson Disease : Potential Mechanisms . -
pubmed
MATERIAL AND METHODS We validated the efficacy of a Bushen Zhichan recipe combined with
levodopa in a
rodent Parkinson disease model and explored its possible mechanisms . -
pubmed
Methods : We evaluated the presence of
Pseudomonas aeruginosa ,
Staphylococcus aureus ,
Stenotrophomonas maltophilia ,
Achromobacter xylosoxidans and
Serratia marcescens in sputum and nasal lavage of 59 patients with
CF , and also collected saliva and used toothbrushes from 38 of them . -
pubmed
In this study , we attempted to quantitatively evaluate sensory symptoms in
patients with
cervical myelopathy according to lesion level using PainVision(R ) . -
pubmed
The results were analyzed for their correlation with magnetic resonance imaging ( MRI ) data , visual analog scale ( VAS ) scores , and
patient functional status assessed by the Japanese Orthopaedic Association ( JOA ) and JOA
Cervical Myelopathy Evaluation Questionnaire ( JOACMEQ ) scores . -
pubmed
This indicates that both the distribution and intensity of
sensory abnormalities are important for neurological level diagnosis in
patients with
cervical myelopathy . -
pubmed
Colletotrichum capsici is a major phytopathogen with a broad host range which causes
anthracnose disease . -
pubmed
BACKGROUND AND PURPOSE : Although developmental
venous anomalies have been frequently studied in adults and occasionally in
children , data regarding these entities are scarce in neonates . -
pubmed
MATERIALS AND METHODS : We reviewed parenchymal abnormalities and angioarchitectural features of 41 neonates with
developmental venous anomalies ( 20
males ; mean corrected age , 39.9 weeks ) selected through a radiology report text search from 2135 neonates who underwent brain MR imaging between 2008 and 2019 . -
pubmed
At a
patient level , multiplicity ( P = .002 ) was significantly associated with the presence of > = 1 complicated
developmental venous anomaly . -
pubmed
METHODS : Data on 97
patients with
atrial fibrillation and
hypertension treated in our hospital were collected from September , 2018 to December , 2019 . -
pubmed
CONCLUSION : Our findings show that rs6843082 SNP leads to the
warfarin dose response differences that were observed in
patients with
atrial fibrillation and
hypertension . -
pubmed
In this report , we detail a case of probable
CIE in an 84 - year - old
woman following a normal diagnostic coronary angiography ( CAG ) that involved 20 mL of the low - osmolar , non - ionic monomeric ,
iodine - based contrast agent
iopromide ( Ultravist 370 ) . -
pubmed
The
patient was unconscious and presented with
hemiparesis ,
hemianopia , recurrent
seizures , and
cardiac and respiratory arrest within minutes to hours following the procedure . -
pubmed
Strawberry tongue is a useful diagnostic feature in various diseases such as
Kawasaki disease ,
TSS ,
scarlet fever , and group A
streptococcal pharyngitis . -
pubmed
METHODS : We collected 587
CC samples , 41
colitis tissues and 114
pericarcinomatous tissues , as well as corresponding clinicopathological data about the
patients who contributed them . -
pubmed
Eighty - nine studies were identified examining healthy
adults and
patients with
neuropsychiatric disorders including
depression ,
chronic pain ,
post - stroke deficits , and
movement disorders . -
pubmed
officinale rhizome revealed their possibility in preventing the occurrence of
atherosclerosis , unsafe levels of some trace elements were recorded in
M. - pubmed
The Kaplan - Meier method was used to evaluate the 10 - year overall survival ( OS ) and 10 - year
cancer specific survival ( CSS ) for
patients with
SBC . -
pubmed
The incidence of
SBC in RC
patients who received RT was higher than the US general population ( SIR , 1.35 ; 95 % CI , 1.19 - 1.53 , P<0.05 ) , and decreased with increasing age at diagnosis , and increased with time since diagnosis . -
pubmed
In the following study ,
estradiol and
testosterone plasma concentration were measured and evaluated in 18
women with
polycystic ovaries , as one of the factors involved in the antiestrogenic response to
Clomiphene Citrate . -
pubmed
[
Oxygen medicinal pulverization in the treatment of stenosing
diseases of the respiratory tract in
children ] . -
pubmed
Twelve serum protein profiles in
children with
acute nonbacterial gastroenterocolitis . -
pubmed
In thirty
children hospitalized with acute benign , short - duration
gastroenterocolitis , no obligate pathogens were isolated from stools . -
pubmed
In 40
women who had received radiotherapy for gynecologic
carcinoma , biopsy was performed because
recurrence of the
tumor was clinically and/or cytologically suspected . -
pubmed
When appropriately stimulated ( even in the absence of phagocytosis ) ,
human polymorphonuclear leukocytes release and/or generate proinflammatory materials and substances capable of provoking
tissue injury . -
pubmed
The BP - positive samples were from 6
children with evidence of severe acute
brain damage leading to
death in 5 cases : i.e. -
pubmed
, 2 term newborns with
perinatal asphyxia , a 4 week - old
child with severe
convulsions , a 3 year - old boy with
hypoxia due to
laryngitis , and a 12 year - old girl with
encephalitis . -
pubmed
Experimental
chronic renal failure in the
rat by electrocoagulation of the renal cortex . -
pubmed
Comparison of
5 - episisomicin (
Sch 22591 ) ,
gentamicin ,
sisomicin , and
tobramycin in treatment of experimental
Pseudomonas infections in
mice . -
pubmed
Infection of
man and chimpanzees with the
hepatitis B virus (
HBV ) is associated with diffuse
hepatocellular infection and variable manifestations of disease which may not only reflect the character of the host immune response , but also depend upon differences in the cellular biology of this minimally cytopathic or noncytopathic agent . -
pubmed
Current information of the biology and immunology of
HBV and other viruses has been integrated into a hypothesis to explain the pathogenesis of
injury and events associated with persistent
infection . -
pubmed
In 19
patients with
meningiomas of the olfactory fossa the author established a certain development of the psychopathological symptomatology . -
pubmed
No age - related changes in threshold were observed in
mice of either
strain . -
pubmed
Permeability alterations and efficacy in
patients with
small bowel obstruction . -
pubmed
One - hundred unselected
children presenting with partial motor
seizures were subjected to clinical work - up and cranial computed tomography ( CT scan ) . -
pubmed
On these , 56
patients had either a ring ( 35
patients ) or a disc - like ( 21
patients ) enhancing lesion which coincided with the probable site of origin of the
seizures in all cases . -
pubmed
Four
patients showed a
spot of
calcification in the area of the original lesion and another two showed a typical ' target sign ' , i.e. -
pubmed
It is concluded that these ring or disc lesions represent
tuberculomas which are , thus , the commonest cause of partial motor
seizures in
children in this area . -
pubmed
The findings described here demonstrate that
TW may occur in
patients with
brain tumor involving subcortical midline structures . -
pubmed
Resistance to cytotoxic agents is a common clinical problem encountered in the treatment of
human myelodysplastic syndromes (
MDS ) and
acute myeloblastic leukaemia (
AML ) . -
pubmed
In addition , peripheral blood or bone marrow cells from 66
patients with
MDS and
AML have been screened for gene amplification and 40 cases for increased mRNA expression . -
pubmed
[ Detection of functional
myocardial insufficiency in
patients with
ischemic heart disease during loading tests ] . -
pubmed
Blood samples were collected twice weekly over a nine month period from 24 Thoroughbred
racehorses in training at Newmarket to study the effects of daily training schedules and stage of oestrous cycle on serum enzyme levels and clinical signs of equine
exertional myopathy . -
pubmed
Traditional flat race training may not be ideal in this respect and it is suggested that , for
horses with an observed tendency towards exertional
myopathy , more consistent and longer periods of less strenuous exercise may be advantageous . -
pubmed
[ Clinico - catamnestic study of
patients with
paroxysmal - progressive schizophrenia with a history of affective ,
anxiety - affective and
affective - hallucinatory attacks in childhood / and full - blown hallucinatory - delusional attacks in adolescence ] . -
pubmed
Clinical follow - up covered 40
patients with
paroxysmal progressive schizophrenia with a history of 52 affective ,
anxiety - affective and affective - hallucinatory attacks at the age of 0 - 10 years and of 70
hallucinatory - delusional attacks at the age of 11 - 17 years and older . -
pubmed
Therefore a single dose schedule was introduced with
Netilmicin given to 600
patients suffering from uncomplicated
gonorrhea in order to evaluate the efficacy and safety of the drug . -
pubmed
Gonorrhea was also clinically cured in all
patients . -
pubmed
[
Estrogen excretion in
patients with
chorioepithelioma of the uterus ] . -
pubmed
[ Lesions of
vitamin E and
selenium deficiencies in
poultry and their pathogenesis ] . -
pubmed
Effect of
streptozotocin diabetes on the hypothalamic - pituitary - thyroid axis in the
rat . -
pubmed
Studies of the hypothalamic - pituitary - thyroid axis have been performed in
streptozotocin (
STZ)-
diabetic Wistar rats and their controls . -
pubmed
The fact that
diabetes caused a reduction in the hypothalamic
TRH content indicates that the primary cause of pituitary - thyroid alterations in
STZ -
diabetic rats lies in the hypothalamus , although the metabolic imbalance induced by
diabetes and , in less degree , by
undernutrition could also be partly responsible for some of the described modifications . -
pubmed
The late fetal effect of chronic alcoholization in two
strains of
mice ( RAP and RAP female x CBAT6 male ) was controlled . -
pubmed
The importance of skin biopsy in
patients presenting with suspected
urticaria pigmentosa is emphasized . -
pubmed
A case of
paraganglioma of parasellar origin in a 7 - year - old
girl is described . -
pubmed
Further studies of the concentration of
magnesium ion (
Mg ++ ) in blood from
patients with
autoimmune diseases . -
pubmed
At an optimal concentration of
magnesium , highly virulent wild
strains of
Yersinia enterocolitica serotype O : 8 , with an LD50 , for
mice , of less than 10(3 ) cell intravenously , had an in - vitro requirement for
calcium at 37 degrees C but not at 26 degrees C. Avirulent wild
strains of
Y. - pubmed
Successful treatment of
anemia seems to improve the quality of life of
cancer patients . -
pubmed
Transfusion therapy should be considered more carefully in relation with some data showing the possible negative influence of allogeneic blood derivatives on the progression of
tumors , especially in
patients immunodeficient after high dose chemotherapy and actinotherapy . -
pubmed
A 28 - year - old
woman with
epilepsy developed the new onset of
paroxysmal tongue tingling during subdural electrode monitoring . -
pubmed
Human T - lymphotropic virus type I - associated uveitis in
patients with
Graves ' disease treated with
methylmercaptoimidazole . -
pubmed
Human T - lymphotropic virus type I ( HTLV - I ) is responsible for a certain form of
uveitis [
HTLV - I - associated uveitis (
HAU ) ] . -
pubmed
A previous history of
Graves ' disease has been reported in 9 - 17 % of the
patients with
HAU . -
pubmed
Five of 25 HTLV - I - positive
patients with
Graves ' disease developed
HAU . -
pubmed
Within a few months before the onset of
uveitis , 3
patients were
hyperthyroid , and 2 were
hypothyroid . -
pubmed
In 2 of 5
patients , an exacerbation of
uveitis occurred soon after the readministration of
MMI for the
relapse of
hyperthyroidism . -
pubmed
None of the 367 HTLV - I negative
patients with
Graves ' disease nor 22 HTLV - I - positive
patients with
chronic thyroiditis or
nodular goiter developed
uveitis . -
pubmed
The furcation involvement of 100 molars in 25
patients suffering from moderate to advanced
periodontitis was investigated . -
pubmed
We used anti - AGE antibodies to localize AGEs within kidney specimens obtained from both
diabetic and nondiabetic
individuals . -
pubmed
OBJECTIVES : The purpose of this study has been to investigate by ultrasonographic methods the flow velocities of cerebral arteries because increased blood viscosity due to haematocrit elevation can cause neurological symptoms in
polycythaemia vera
patients , because of the resulting decrease in cerebral flow . -
pubmed
CONCLUSIONS : A decrease in cerebral flow could be a risk for multifocal micro - ischaemic
cerebral infarctions leading , after several years , to a multi -
infarct dementia ; an early reduction in erythrocyte burden should be very useful in
polycythaemic patients in preventing
lacunar lesions . -
pubmed
The injection of antibodies induces the development of immunological memory ; as a result , the
animals are primed to respond to the injection of
influenza vaccine . -
pubmed
From March 1991 to June 1993 50
patients with local advanced
NSCLC ( mediastinoscopy obligatory ) have been entered into an ongoing trial with preoperative chemotherapy and simultaneous chemo-/radiotherapy , followed by re - mediastinoscopy and surgery . -
pubmed
Suppression of tumorigenicity in
human teratocarcinoma cell line
PA-1 by introduction of chromosome 4 . -
pubmed
Immature ovarian
teratocarcinomas are highly malignant with only 30 - 60 % of
patients surviving for 2 years after diagnosis . -
pubmed
We have used microcell fusion to introduce individually tagged normal
human chromosomes into the
PA-1 human teratocarcinoma cell line . -
pubmed
We conclude that there is a putative
tumor suppressor gene on
human chromosome 4 whose expression interferes with the tumorigenicity of
PA-1 cells . -
pubmed
A prospective one - year follow - up study with somatosensory potentials evoked by stimulation of the median nerve in
patients with
cerebral infarct . -
pubmed
Somatosensory potentials evoked by stimulation of the median nerve ( median nerve SEPs ) were studied in a prospective and sequential series of 40
patients with first supratentorial and nonhaemorrhagic
cerebral infarct . -
pubmed
In 35
patients the SEPs were recorded three times during the first year after the
stroke . -
pubmed
The location of the infarcted zone was reflected in the number of detected abnormalities : most
patients with
infarct changes extending to the gray matter of the Rolandic cortex showed abnormalities in the median nerve SEPs , and all
patients with involvement of both precentral and postcentral cortical gray matter had abnormal median nerve SEPs . -
pubmed
In the entire
patient group when both latency and amplitude abnormalities were included about half ( 48 % ) of the
patients had abnormal median nerve SEPs a week after the
stroke , 39 % 2 - 3 months after the
stroke and 29 % about one year after the
stroke . -
pubmed
Occurrence of polyclonal B - cell activation after experimental
infection with
Yersinia enterocolitica O:3 . -
pubmed
Changes of distribution of
platelet activating factor in the lung of
rats with
hypoxic pulmonary hypertension . -
pubmed
MATERIAL AND METHODS : Fifteen of 30 male
Wistar rats were exposed to
hypoxia for 3 weeks , and another 15
rats served as controls . -
pubmed
RESULTS : The
rats developed
pulmonary hypertension and
right ventricular hypertrophy after hypoxic exposure . -
pubmed
Under the light microscope ,
PAF is distributed on the vascular and alveolar walls of normal lung , and the content of
PAF in the lung of
rats with
hypoxic pulmonary hypertension are remarkably higher than those of normoxic controls . -
pubmed
CONCLUSIONS :
PAF plays not only a physiological role in the
rat lung , but also a pathophysiologic role in
hypoxic pulmonary hypertension . -
pubmed
We have treated by the " rendezvous " technique two
patients suffering from
pancreatic fistula complicating
pancreatic pseudocysts . -
pubmed
[ Internal osteosynthesis after unstable
pelvic ring fracture in a 3 - year - old
child ] . -
pubmed
Here we describe the rare case of a
gastric duplication cyst in a 59 - year - old
patient . -
pubmed
Blood pressure profile in
patients with
microvascular angina . -
pubmed
Normotensive
patients with
microvascular angina exhibit increased
diastolic blood pressure and blood pressure loads during daily activities and decreased diurnal variation of
systolic blood pressure , compared with age- and sex - matched normotensive controls . -
pubmed
PURPOSE : To examine how different operative measures influence the surgical outcome in
patients with
fibrous dysplasia of bone . -
pubmed
METHODS : 118
dysplastic fibrous lesions of bone were surgically treated and reviewed in 70
patients between 1983 to 1993 ( eleven years ) with a median follow - up of six and a half years . -
pubmed
Reconstruction with cortical grafts or bone chips from the bone bank , if necessary in combination with a durable osteosynthesis in mechanically demanding locations , or solely bone cement in mechanically less demanding areas , reduces the revision rate in
patients with monoostotic and
polyostotic fibrous dysplasia . -
pubmed
The aim of this study was to determine the accuracy of clinical tests compared to colour duplex imaging in
patients with primary
varicose veins using a prospective , blinded comparison study . -
pubmed
A total of 44
patients ( 70 limbs ) with primary , previously untreated
varicose veins presenting to the vascular laboratory of a university teaching hospital were studied . -
pubmed
The
patients underwent physical examination using the
cough test , the tap test , Trendelenbergs ' test , Perthes ' test and hand - held Doppler ( HHD ) assessment prior to undergoing colour duplex scanning . -
pubmed
The ability to produce experimental
endolymphatic hydrops in the
guinea pig secondary to surgical occlusion of the endolymphatic sac and duct has been useful in studying various aspects of
Meniere ' s disease ( 2 ) . -
pubmed
Evaluation of the potency of BIKEN inactivated Japanese
Encephalitis vaccine and DNA vaccines in an intracerebral
Japanese Encephalitis virus challenge . -
pubmed
Fourteen
girls and 11
boys with a median age of 20 months ( 2 months , 10 years ) presented with 26 separate
tumors . -
pubmed
Five
patients ( all with diffuse type ) had up to 3
recurrences . -
pubmed
CONCLUSIONS :
Patients with
focal lipoblastoma are unlikely to require further surgery after initial resection . -
pubmed
Patients with
diffuse lipoblastoma (
lipoblastomatosis ) are likely to have recurrent disease ( usually within 2 years ) and should undergo close follow - up . -
pubmed
The clinical characteristics and the kinetics of the disposition of the
hepatomegaly associated with acute , uncomplicated
Plasmodium falciparum malaria were investigated in 162
children in an endemic area of Nigeria . -
pubmed
Hepatomegaly was significantly more common in the younger than in the older
children . -
pubmed
In the
children in whom
hepatomegaly did not resolve , a reduction in liver size of & lt ; 17 % by the time
parasitaemia was cleared ( usually on day 3 ) was associated with non - resolution of
hepatomegaly by days 7 or 14 of follow - up . -
pubmed
In the
children who had complete clearance of
parasitaemia and resolution of
hepatomegaly , there was no significant relationship between the
parasitaemia - derived conventional indices of therapeutic response [ i.e. -
pubmed
In the
children with
drug - sensitive P. falciparum infections and in whom
hepatomegaly completely resolved , the area produced by plotting liver size against time ( i.e. -
pubmed
These results indicate that routine clinical measurement of the liver size in children with
hepatomegaly during acute , uncomplicated ,
P. - pubmed
Prior stress ameliorates
caerulein - induced
pancreatitis in
rats . -
pubmed
Tobacco use in households with
asthmatics . -
pubmed
A total of 169 powder - naive
patients ( mean age 40 years ) with
asthma or
chronic obstructive pulmonary disease (
COPD ) were enrolled in a randomized crossover comparison of both inhalers . -
pubmed
We present a novel Fn - binding protein of
group A streptococcus serotype M3 and
M18 strains isolated from patients with
toxic shock - like syndrome (
TSLS ) . -
pubmed
Moreover , mortality was decreased in
mice infected with the mutant
strain in comparison to the wild type . -
pubmed
These clinical features overlap considerably with other co - circulating respiratory viruses such as
respiratory syncytial virus and
parainfluenza virus . -
pubmed
Pneumonia due to
Mycoplasma hominis in a healthy adult . -
pubmed
A case of
pneumonia due to
Mycoplasma hominis in a healthy adult is presented . -
pubmed
The emergence of Ph- ,
trisomy -8 + cells in
patients with
chronic myeloid leukemia treated with
imatinib mesylate . -
pubmed
OBJECTIVE : To describe clinical and laboratory features of a cohort of
patients with
chronic myelogenous leukemia (
CML ) who developed Ph(- ) ,
trisomy 8(+ ) metaphases while on treatment with
imatinib mesylate . -
pubmed
PATIENTS AND METHODS : Conventional cytogenetics and triple - color interphase fluorescence in situ hybridization were used to identify 5 of 310 studied
patients who , on follow - up analysis , had Ph(- ) ,
trisomy 8(+ ) cells while on therapy . -
pubmed
All
patients developed grade 3 or 4
neutropenia and
thrombocytopenia during treatment . -
pubmed
CONCLUSIONS : While on treatment with
imatinib mesylate a small group ( less than 5 % ) of
patients with
CML developed Ph(- )
trisomy 8(+ ) clone associated with
pancytopenia . -
pubmed
A 61 - year - old
man with
congestive heart failure was referred to our hospital and diagnosed as
atrial septal defect (
ASD ) [ Qp / Qs = 1.6 ] with chronic
atrial fibrillation . -
pubmed
MATERIALS AND METHODS : Twelve consecutive
patients with their first
middle cerebral artery ( MCA ) infarction were included . -
pubmed
Specific inhibition of Hh signalling by the naturally occurring
plant alkaloid
cyclopamine provides the opportunity for pharmacologic assessment of the role of Hh signalling in these
tumors . -
pubmed
METHODS : 63 approximal
carious lesions were restored in 38
patients by two experienced operators . -
pubmed
Consequently , we performed a phase II trial in
patients with advanced
melanoma to explore this approach . -
pubmed
Six
patients continue to show no signs of
tumor progression for 3 + , 5 + , 10 + , 24 + , 60 + , and 72 + months . -
pubmed
METHODS : Eighty - five
patients with
postoperative nausea and vomiting were included in this prospective , single - blind study . -
pubmed
56 lesions were treated ; 26
bedsores , 11
venous sores , 10 mixed
lesions and 9 other types , they had an average presence on the
patient of 270 ( + /- 684 ) days , the medium was 85 days and the mode 365 days . -
pubmed
[ Antiatherogenic effect of Huajiao volatile oil on experimental
atherosclerosis in
guinea pigs ] . -
pubmed
METHODS :
Atherosclerotic guinea pig models were duplicated by feeding high lipid forage . -
pubmed
CONCLUSION : Huajiao volatile oil has an inhibitory effect on the development of experimental
atherosclerosis lesions in
guinea pigs . -
pubmed
The purpose of this study was to identify the metabolic features that place
patients with
type 2 diabetes at increased risk for
uric acid nephrolithiasis . -
pubmed
Patients with
type 2 diabetes and UASF had lower 24 - h urine pH than NV . -
pubmed
With increasing urine
sulfate , NV and
patients with
type 2 diabetes had a similar rise in urine
ammonium , whereas in UASF ,
ammonium excretion remained unchanged . -
pubmed
The main risk factor for
uric acid nephrolithiasis in
patients with
type 2 diabetes is a low urine pH. -
pubmed
Higher body mass and increased acid intake can contribute to but can not entirely account for the lower urine pH in
patients with
type 2 diabetes . -
pubmed
METHODS : Thirteen
patients who were diagnosed with
HHS between 1995 and 2003 were retrospectively assessed . -
pubmed
The mean age of
HHS patients was 38.6 + /- 10 years ( 5
women , 8
men ) . -
pubmed
HHS was related to an infectious etiology in 6 of 13
patients :
tuberculosis ( n=3 ) ,
cytomegalovirus ( CMV ) infection ( n=2 ) ,
Escherichia coli (
E. - pubmed
coli)-associated
septicemia ( n=1 ) , but
HHS was cured by antimicrobial therapy in only 2 of them ( 1 with
tuberculosis , the other with
E. - pubmed
HHS was related to an infectious etiology in 2
patients unresponsive to antimicrobial treatment , and of unknown etiology in 4 patients . -
pubmed
CONCLUSIONS : We concluded that when
HHS does not respond to treatment of the underlying
infection , or is of unknown etiology in immunocompromised
patients , high - dose IVIg therapy should be administered . -
pubmed
We examined if neocortical epileptogenic regions can be circumscribed by quantifying local long - range temporal ( auto-)correlations ( LRTC ) with detrended fluctuation analysis of
seizure - free ongoing subdural EEG activity in 4 frequency bands in 5
patients . -
pubmed
A 67 - year - old
man initially presented with an 8 - year history of right
trigeminal neuralgia . -
pubmed
This article reports the case of an intraosseous
schwannoma located in the mandibular symphysis of an 11 - year - old
boy . -
pubmed
The diagnosis of
BO was based on the presence of respiratory symptoms and air - trapping on expiratory lung high - resolution computed tomography in all
patients , associated with irreversible
airflow obstruction in seven cases . -
pubmed
However , the pathogenic mechanism of
dengue virus (
DV)-induced
hemorrhage awaits clarification . -
pubmed
We established a
mouse model of DV
hemorrhage using immunocompetent
C57BL / 6 mice by injecting DV serotype 2
strain 16681 intradermally . -
pubmed
While inoculation of 3 x 10(9 ) PFU of DV induced systemic
hemorrhage in all of the
mice by day 3 of
infection , one out of three of those injected with 4 x 10(7 ) to 8 x 10(7 ) PFU developed
hemorrhage in the subcutaneous tissues . -
pubmed
The
mice that were inoculated with 4 x 10(7 ) to 8 x 10(7 ) PFU but that did not develop
hemorrhage were used as a basis for comparison to explore the pathogenic mechanism of
dengue hemorrhage . -
pubmed
The results showed that
mice with severe
thrombocytopenia manifested signs of vascular leakage and
hemorrhage . -
pubmed
A reappraisal of the safety of 50 %
dextrose administration in
patients with
hypoglycemia . -
pubmed
METHOD : We have evaluated 40
women , divided into four groups by the model of
postoperative pain treatment : control group ( only opioid ) and experimental group ( combination of i.v . -
pubmed
Protective role of lactobacilli in
Shigella dysenteriae 1 - induced
diarrhea in
rats . -
pubmed
Nevertheless , in vivo effects of
Lactobacillus during
Shigella infection have not been evaluated . -
pubmed
The present study evaluated the effect of
Lactobacillus rhamnosus and
Lactobacillus acidophilus on neutrophil infiltration and lipid peroxidation during
Shigella dysenteriae 1 - induced
diarrhea in
rats . -
pubmed
METHOD : Thirty
patients with
perennial allergic rhinitis were treated by specific immunotherapy for three years . -
pubmed
Controlled group were 30 perennial
allergic rhinitis patients who were treated with medication only ( antihistamines and intranasal
corticosteroids ) when necessary . -
pubmed
Healthy group were 10 healthy
people without
allergic rhinitis . -
pubmed
( 3 ) Thirty
patients with
allergic rhinitis received 3530 times immunotherapy , their local and systemic side - effect were observed , recorded and analyzed during the treatment , the number of
patients who got systemic side - effect was 4 cases , the percent of side - effect was 0.17 % ( 6/3530 ) ; the number of
patients who got local side - effect was 12 cases , the percent of local side - effect was 1.53 % ( 54/3530 ) . -
pubmed
With a lifetime incidence of up to 12 % in
man and 6 % in woman ,
nephrolithiasis is a major health problem worldwide . -
pubmed
In this brief review , we summarize the studies assessing the heritability of
hypercalciuria and pinpoint recently identified
human genetic disorders as well as relevant
animal models that provided new insights into the segment - specific tubular handling of
calcium and the pathophysiology of
renal hypercalciuria and
kidney stones . -
pubmed
Predictive factors for
tumor response and long term outcome should be developed for a better selection of the
patient population who will benefit from these treatments . -
pubmed
Borrelia burgdorferi , the causative agent of
Lyme disease , activates multiple signalling pathways leading to induction of pro - inflammatory mediators at sites of
inflammation . -
pubmed
The effect of
monohydroxyethylrutoside on
doxorubicin - induced
cardiotoxicity in
patients treated for
metastatic cancer in a phase II study . -
pubmed
The purpose of this study was to investigate the cardioprotective effect of the semisynthetic
flavonoid 7 - monohydroxyethylrutoside (
monoHER ) on
doxorubicin (
DOX)-induced
cardiotoxicity in a phase II study in
patients with
metastatic cancer . -
pubmed
Eight
patients with
metastatic cancer were treated with
DOX preceded by a 10 min i.v . -
pubmed
Although there is a considerable variability in few investigated
patients , it was indicative that
monoHER enhanced
DOX - induced
cardiotoxicity . -
pubmed
However , the antitumour activity of
DOX seemed better than expected : three of the four
patients with
metastatic soft - tissue sarcoma had a partial remission and the fourth
patient stable disease . -
pubmed
It is likely that the relatively high dose of
monoHER is responsible for the lack of cardioprotection and for the high response rate in
patients with
soft - tissue sarcoma possibly by depleting the
glutathione defense system in both heart and
tumour . -
pubmed
In vivo
porcine model of reperfused
myocardial infarction : in situ double staining to measure precise
infarct area / area at risk . -
pubmed
OBJECTIVES : The aim of this study is to evaluate a catheter - based
porcine model for reperfused
myocardial infarction and investigate the appropriate location and duration of the occlusion . -
pubmed
Myocardial infarction was successfully induced in all 72
animals and in situ double - staining with Evans blue dye and
2,3,5 - triphenyltetrazolium chloride was performed to delineate area at risk for
ischemia and infarcted myocardium . -
pubmed
The current study demonstrated that 60 - min mid
LAD occlusion can be the most feasible to serve as a
porcine reperfused
myocardial infarction model . -
pubmed
Aeromonas sobria prostatitis and
septic shock in a healthy
man with chronic alcoholic consumption . -
pubmed
Prostate infection caused by
Aeromonas sobria has not been reported in the literature . -
pubmed
Based on our rare case , we suggest to clinical physicians that
prostatitis might be considered in healthy male patients with
A. - pubmed
PURPOSE : To investigate the safety , tolerability , and bioactivity of intravenous infusions of
bevacizumab in
patients with
choroidal neovascularization (
CNV ) attributable to causes other than age - related
macular degeneration . -
pubmed
METHODS : Ten
patients with
CNV received infusions of 5 mg / kg of
bevacizumab . -
pubmed
All
patients except one showed a reduction in area of
CNV with a median reduction of 43 % . -
pubmed
CONCLUSIONS : Despite the small number of
patients studied , the marked improvement in VA accompanied by prominent reductions in foveal thickness ,
fluorescein leakage , and area of
CNV suggest a beneficial effect . -
pubmed
It may be worthwhile to consider further evaluation of systemic
bevacizumab in young
patients with
CNV . -
pubmed
No
patients had
thigh pain and no
patients had aseptic loosening . -
pubmed
Controlled
hypotension in
adults undergoing
choroidal melanoma resection : comparison between the efficacy of
nitroprusside and
magnesium sulphate . -
pubmed
METHODS : Forty adult
patients undergoing
choroidal melanoma resection and anaesthetized with 2.5 mg kg(-1 )
propofol , followed by a constant infusion of 120 microg kg(-1 ) min(-1 ) , and
remifentanil 1 microg kg(-1 ) , followed by a continuous infusion of 0.25 microg kg(-1 ) min(-1 ) , were randomly assigned to two groups to receive either
magnesium sulphate or
sodium nitroprusside . -
pubmed
CONCLUSION :
Magnesium sulphate controlled
hypotension , reduced intraoperative pressure and provided good surgical conditions for
choroidal melanoma resection with no need for additional use of a potent
hypotensive agent in
adults . -
pubmed
Cardiac effects of continuous and bilevel positive airway pressure for
patients with
heart failure and
obstructive sleep apnea : a pilot study . -
pubmed
BACKGROUND :
Obstructive sleep apnea (
OSA ) is prevalent in
patients with
heart failure . -
pubmed
Treatment with continuous positive airway pressure ( CPAP ) improves systolic function in
patients with
heart failure . -
pubmed
The intermediate - term effect of bilevel PAP on left ventricular ejection fraction ( LVEF ) in
patients with stable
heart failure and
OSA has not been compared to the effect of CPAP . -
pubmed
CONCLUSION : This pilot randomized controlled trial suggests that bilevel
PAP is superior to CPAP in improving LVEF in
patients with
systolic dysfunction and
OSA . -
pubmed
BACKGROUND : Approximately one - half of
hypertensive individuals are salt sensitive , and
animal models of
human hypertension also exhibit increased blood pressure when exposed to high - salt diets . -
pubmed
Incidental
hypokalemia in ambulatory
patients . -
pubmed
There were no differences between patients with ABECB treated with SSPs and those treated with
trimethoprim , alone or in combination with a
sulfonamide , in treatment success ( intention - to - treat
patients : n = 262 , odds ratio [ OR ] 1.68 , 95 % confidence interval [ CI ] 0.91 - 3.09 ; clinically evaluable
patients : n = 246 , OR 1.59 , 95 % CI 0.79 - 3.20 ) or number of drug - related adverse events in general ( n = 186
patients , OR 0.37 , 95 % CI 0.11 - 1.24 ) , frequency of
diarrhea or
skin rashes , or number of withdrawals due to adverse events ( n = 179
patients , OR 0.27 , 95 % CI 0.07 - 1.03 ) . -
pubmed
METHODS : The association of
fentanyl and 0.75 %
bupivacaine for eye blockade and postoperative analgesia was evaluated in 164
patients undergoing
cataract extraction with implantation of intraocular lens ( extracapsular technique ) . -
pubmed
Drug - induced acute
pancreatitis in
children receiving chemotherapy for
acute leukemia : does
propofol increase the risk ? -
pubmed
BACKGROUND : The use of
propofol is controversial in
patients with a history of acute
pancreatitis or those taking drugs , including certain chemotherapeutic drugs , that are associated with
pancreatitis . -
pubmed
METHODS : To investigate this issue , we reviewed the medical records of all
children who were diagnosed with
pancreatitis while receiving chemotherapy for
acute leukemia during a 5 - year period . -
pubmed
CONCLUSION :
Propofol can be considered for general anesthesia in
children who are receiving chemotherapeutic drugs that are themselves associated with acute
pancreatitis or those who have a history of chemotherapy - induced
pancreatitis . -
pubmed
While
infection with
C. - pubmed
difficile
strains of public health significance continue to emerge , and reliable genotyping methods for epidemiological investigations and global surveillance of
C. - pubmed
Six
women later developed
PE and 9 remained normotensive . -
pubmed
CONCLUSION : This small observational study showed that serum CC is raised as early as the second trimester in
women who subsequently develop
PE in third trimester . -
pubmed
Leptospirosis is a neglected
infectious disease that constitutes a threat to both
humans and animals . -
pubmed
Acute
toxicity of
nitrite and
ammonia to
Daphnia similoides of different developmental stages : using the modified Gaussian model to describe . -
pubmed
Shigella is a Gram - negative
human pathogen that causes
diarrhea in
humans . -
pubmed
METHODS : A retrospective observational study was conducted in all
critically ill patients who had been prescribed nutritional support , throughout one year , in an Intensive Care Unit . -
pubmed
These sensitive and specific ancillary tools are useful for confirming ambiguous diagnoses suspected by light microscopy and for guiding therapeutic decisions , assessing prognosis , and monitoring
patients for residual
neoplastic disease after therapy . -
pubmed
Among 161
patients with
acute myeloid leukemia ( non - M5 subtype ) , estimated median overall survival was 39 , 29 , and 37 months , respectively , in the
daunorubicin , standard - dose
homoharringtonine , and high - dose
homoharringtonine treatment groups ( P = .53 ) . -
pubmed
In the 93
patients with
acute myeloid leukemia - M5 subtype , there was a significant difference in estimated median overall survival : 24 , 24 , and 52 months , respectively , in the
daunorubicin , standard - dose
homoharringtonine , and high - dose
homoharringtonine treatment groups ( P = .003 ) . -
pubmed
High - dose
homoharringtonine does not clearly increase the complete remission rate of elderly
patients with
acute myeloid leukemia . -
pubmed
However , in the subset of elderly
patients with
acute monocytic leukemia , high - dose
homoharringtonine as a first - line regimen prolonged overall survival with minimal toxicity . -
pubmed
These findings demonstrated the presence of both genome - wide and segmental duplications in the
apple genome and provided further insights into the complex
polyploid ancestral origin of the
apple . -
pubmed
In the present report we show that
tamoxifen is endowed with significant inhibitory property against
human platelet aggregation . -
pubmed
Twenty
individuals ( 13 females and 7 males , average age 40.1 + - 13.4 ) with stabilization classification
LBP and 19 controls ( 10 females and 9 males , average age 30.3 + - 8.7 ) participated in this study . -
pubmed
BACKGROUND : In Honduras ,
chloroquine and
primaquine are recommended and still appear to be effective for treatment of
Plasmodium falciparum and
Plasmodium vivax malaria . -
pubmed
Because of the environmental and industrial importance of the class of
aromatic amines , we apply the approach to a previously published QSAR on the
Salmonella typhimurium mutagenicity of these chemicals . -
pubmed
Their cooperation , by completing a structured questionnaire and allowing the direct observation of three subjects , enabled us to carry out a study on a total of 75
patients suffering from
AH . -
pubmed
BACKGROUND :
Mycobacterium tuberculosis , the causative agent of
tuberculosis , has a remarkable ability to usurp its host 's innate immune response , killing millions of infected people annually . -
pubmed
Variants of
human papillomavirus ( HPV ) type 31 have been shown to be related both to risk of
cervical lesions and racial composition of a population . -
pubmed
Correlation of conventional and conformal plan parameters for predicting
radiation pneumonitis in
patients treated with
breast cancer . -
pubmed
Only four
patients developed symptomatic
RP , 4 with 4 - FRT and one with 2 - FRT . -
pubmed
However , delayed
RAE could cause the
patient to reach a life - threatening
cachexic state and could increase the risk of morbidity and mortality due to severe
proteinuria - induced
hypoalbuminemia . -
pubmed
The use of
( 41 ) C kinetic modeling in the Ossabaw
swine provides an approach for assessing soft tissue calcification in an
atherosclerotic and normal state to address research gaps . -
pubmed
reported significant improvement in neurological outcomes in
MS patients who underwent percutaneous transluminal angioplasty ( PTA ) . -
pubmed
OBJECTIVES : To retrospectively evaluate the neurological outcomes in
MS patients who underwent PTA . -
pubmed
Patients with clinically isolated
syndrome or progressive forms of
MS were excluded . -
pubmed
Primary endpoint was the proportion of
relapse - free
patients at 1 year . -
pubmed
There was no difference among the
patients who stopped their DMTs with respect to
relapses , EDSS score or new MRI activity . -
pubmed
The basis for initial selection of endemic atoxigenic
strains of
A. - pubmed
Efficacy and safety of autologous bone marrow - derived stem cell transplantation in
patients with
type 2 diabetes mellitus : a randomized placebo - controlled study . -
pubmed
METHODS : Nineteen subjects , 14
men and 5
women ( ages , 20 - 39 years ) without
temporomandibular disorders were examined . -
pubmed
Anticoagulant therapy is the first line of treatment in
CVST but may not be applicable in
patients with
head trauma . -
pubmed
Here , we report on the treatment of 2
patients with
CVST . -
pubmed
Seventeen
patients had an excessive
deformity ( & gt;15 of
varus or valgus ) , twenty - one had moderate valgus alignment ( 5 to 15 of valgus ) , twenty - seven had moderate
varus alignment ( 5 to 15 of varus ) , and thirty - eight had neutral alignment ( & lt;5 of
varus or valgus ) . -
pubmed
The diploid SVP5 line ( 2n=2x=24 ) and
tetraploid regenerants of
S. - pubmed
We have evaluated both invariant and non - invariant populations in the blood and synovial fluid from
patients to assess feasibility of NKT cell - directed manipulations in
RA . -
pubmed
RESULTS : We have confirmed a proliferative defect of iNKT cells in both peripheral blood and synovial fluid from
RA patients , but no changes in baseline frequencies . -
pubmed
MATERIALS AND METHODS : We reviewed 33 consecutive
patients with
type 2 diabetes admitted to Osaka University Hospital for glycemic control . -
pubmed
Hemodynamically stable
patients with
renal injury can be managed conservatively . -
pubmed
The intensive care unit mortality rate was 15 % , and 38 % of the
patients had
postoperative complications . -
pubmed
Myocardial ischemia was diagnosed in only 1.9 % of the
patients . -
pubmed
Recently , there has been controversy about the relationship between the number of lymph nodes removed and survival of
patients diagnosed with lymph node - negative
breast cancer . -
pubmed
Patients were stratified into two groups ( Group A , 10 or fewer
tumor - free lymph nodes removed ; Group B , more than 10
tumor - free lymph nodes removed ) . -
pubmed
Our results revealed that the risk of
death from
breast cancer was significantly associated with
patient age , marital status , histologic grade ,
tumor size , and adjuvant therapy . -
pubmed
The 5- and 10 - year survival rates for
patients with 10 or fewer
tumor - free lymph nodes removed was 88.0 % and 66.4 % , respectively , compared with 69.2 % and 51.1 % , respectively , for
patients with more than 10
tumor - free lymph nodes removed . -
pubmed
For
patients with 10 or fewer
tumor - free lymph nodes removed , the adjusted hazard ratio ( HR ) for risk of
death from
breast cancer was 0.579 ( 95 % confidence interval , 0.492 - 0.687 , P & lt ; 0.001 ) , independent of
patient age , marital status , histologic grade ,
tumor size , and adjuvant therapy . -
pubmed
To examine how fish consumption affects the development and prevalence of
MetS , we systematically reviewed cross - sectional , prospective cohort , and intervention studies conducted among adults (
humans ) and , reporting consumption of fish or seafood as being related to
MetS ( prevalence or incidence ) , where
MetS was defined via an established definition . -
pubmed
METHODS : Hyperoxic
lung injury was induced by exposing to 60 %
O2 in
Spraque - Dawley rats within 6 hours after birth . -
pubmed
Postoperative complications in
patients with
obstructive sleep apnea : a meta - analysis . -
pubmed
CONCLUSIONS : Surgical
patients with
OSA are at increased risk of postoperative
respiratory failure , cardiac events , and ICU transfer . -
pubmed
The impact of
neuropathic pain and other comorbidities on the quality of life in
patients with
diabetes . -
pubmed
We were interested in how
neuropathic pain impairs the quality of life in diabetic
patients and what is the role of comorbidities in this condition . -
pubmed
METHODS : The study included 80
patients with
painful DPN ( group " P " ) and 80
patients with
DPN , but without
neuropathic pain ( group " D " ) . -
pubmed
Clinically , the most pronounced differences between two groups were noted in
sleeping disorders and problems regarding micturition and defecation , which were significantly more expressed in group P. The similar situation was with walking distance and color - doppler sonography of carotid arteries , which were significantly worse in group P. Consequently , subjects in group P were more medicated than the
patients in group D , particularly with
tramadol , antiepileptics and antidepressants . -
pubmed
Parthenolide (
PTL ) is a
sesquiterpene lactone isolated from
feverfew and exhibits potent antitumor activity against various
cancers . -
pubmed
Since certain
flavonoids are potent
bacterial efflux pump inhibitors , we assessed
morin ,
rutin ,
quercetin ,
hesperidin , and
( + ) - catechin for their combined activity with the antibiotics
ciprofloxacin ,
tetracycline ,
erythromycin ,
oxacillin , and
ampicillin against drug - resistant
strains of
Staphylococcus aureus , including
methicillin - resistant
S. - pubmed
The
cytotoxicity of the
flavonoids was additionally evaluated in a
mouse fibroblast cell line . -
pubmed
MATERIALS AND METHODS : A total of 30
patients ( mean age , 19.5 years ) received 147 direct composite additions for teeth recontouring and
diastema closures . -
pubmed
We chose pathogen bacterium
Pseudomonas aeruginosa as a model
strain and evaluated the inhibitory effects of
gentamicin and
ciprofloxacin . -
pubmed
RESULTS : Unlike the robust beneficial effect on anastomosis under uncomplicated conditions , here
GM6001 had a negative impact on anastomotic
wound healing following
colonic obstruction and substantially ( p=0.004 ) more
rats in the
GM6001 group ( 75 % ) than in the control group ( 11 % ) had developed
anastomotic leakage . -
pubmed
Synovial fluid
total protein concentration as a possible marker for
canine idiopathic polyarthritis . -
pubmed
Idiopathic polyarthritis (
IPA ) is a very common inflammatory
arthropathy in the
dog . -
pubmed
METHODS : This prospective study included 37 hips in 37
patients ( mean age 26 + - 9 years ) who were treated with periacetabular osteotomy for symptomatic
acetabular dysplasia and had preoperative and 1 - year follow up dGEMRIC scans . -
pubmed
Patients were eligible if they had symptomatic
acetabular dysplasia with lateral center - edge angle & lt ; 20 and no or minimal
osteoarthritis . -
pubmed
METHODS : A total of 109
patients with
AMI and 58 healthy
subjects as control group were included in the study . -
pubmed
METHODS : Between February 2010 and October 2013 , 147
patients with
acute aortic dissection (
AAD ) were divided into Group 1 ( Stanford A , n = 59 ) and Group 2 ( Stanford B , n = 88 ) . -
pubmed
Suppression of the PLT activation might be future targets of therapy in the prevention of
systemic inflammation in
AAD patients . -
pubmed
We analyzed
patients with
BC before and after NACT for disseminated
tumor cells ( DTCs ) in the bone marrow(BM ) ; comprehensively characterized circulating
tumor cells ( CTCs ) , including stem cell - like
CTCs ( slCTCs ) , in blood to prove the effectiveness of treatment on these cells ; and correlated these findings with response to therapy , progression - free survival ( PFS ) , and overall survival ( OS ) . -
pubmed
Thus , these
patients might benefit from additional second - line treatment protocols including
bisphosphonates for the eradication of
DTCs . -
pubmed
The anti - inflammatory and anti - apoptotic effects of
gallic acid against mucosal
inflammation- and erosions - induced by
gastric ischemia - reperfusion in
rats . -
pubmed
The present study aimed to evaluate the protective effect of
gallic acid on
gastric mucosal lesions caused by
ischemia - reperfusion ( I / R ) injury in
rat . -
pubmed
Forty male
rats were randomly divided into sham , control ( I / R
injury ) and three
gallic acid - pretreated groups . -
pubmed
Pretreated
rats received
gallic acid ( 15 , 30 or 60 mg kg(-1 ) , intraperitoneally ) 30 min prior to the induction of I / R
injury . -
pubmed
OBJECTIVES : To assess and clearly define the repigmentation patterns in a series of
patients with
vitiligo , correlating these with clinicoepidemiological characteristics . -
pubmed
METHODS :
Patients with
vitiligo seen at least at twice ( initial consultation and follow - up visit ) in the Department of Paediatric Dermatology , Hopital Pellegrin des Enfants , Bordeaux University Hospital from 2006 to 2014 were included . -
pubmed
RESULTS : There were 109
patients ( 64 female , 45 male ) mostly with
Fitzpatrick skin type III ( n = 67 , 61 % ) . -
pubmed
OBJECTIVES : The aim of this study was to evaluate sex differences in plaque morphology in stable
coronary artery disease (
CAD )
patients using a multimodality intravascular imaging approach . -
pubmed
METHODS : We retrospectively analyzed data from 383
patients with stable
CAD who were referred for angiography and underwent optical coherence tomography . -
pubmed
BACKGROUND :
Obesity is a risk factor for
breast cancer in postmenopausal
women and is associated with decreased survival and less favorable clinical characteristics such as greater
tumor burden , higher grade , and poor prognosis , regardless of menopausal status . -
pubmed
Alterations of pathways involved in cell cycle control ,
tumorigenesis and metabolism may promote cellular proliferation and provide a molecular explanation for less favorable outcome of
obese women with
breast cancer . -
pubmed
Characterization of anti -
leukemia components from
Indigo naturalis using comprehensive two - dimensional
K562 / cell membrane chromatography and in silico target identification . -
pubmed
In this study , a new strategy combining comprehensive two - dimensional
K562 / cell membrane chromatographic system and in silico target identification was established to characterize active components from
Indigo naturalis , a famous TCM herb that has been widely used for the treatment of
leukemia in China , and their targets . -
pubmed
INTRODUCTION : The purpose of this study was to compare the isolated effects of bonded and conventional spurs on the craniofacial and dentoalveolar complexes of
patients in the mixed dentition with
anterior open bite . -
pubmed
METHODS : The sample included 68
subjects with
anterior open bite and
Class I malocclusion . -
pubmed
The aim of this study was to analyze the clinical characteristics and to explore the rational treatment of
patients with
breast SCC . -
pubmed
METHODS : Between 04/2014 and 04/2015 , 16
patients with deep partial- to full - thickness
burns of the upper extremities underwent enzymatic debridement ( ED ) in our Burn Center and were evaluated for extent of additional surgery ,
wound healing ,
pain management and functional parameters . -
pubmed
Time from
injury to ED was 24.4 h and
patients were able to start physical therapy after 2.0 days but suffered from prolonged
wound closure ( 28.0 days ) . -
pubmed
Asthma therapy is changing from a ' one size fits all ' therapy to a ' precision medicine ' model , where we may prescribe the most appropriate treatment for each
patient . -
pubmed
Whole blood gene expression profiling was performed in 17 and 9
patients diagnosed with
ET and
PMF , respectively . -
pubmed
Our 7 - gene signature may be a useful tool to differentiate between genuine
ET and prePMF but needs to be validated in a larger cohort of "
ET "
patients . -
pubmed
This study was designed to determine the types of histological alterations seen in Nigerian
patients with
NERD . -
pubmed
METHODS : This was a prospective cross - sectional study in which mucosal biopsy was taken from the lower esophagus in
patients with
NERD . -
pubmed
RESULTS : There were 68
patients with
NERD and 60 patients with
nonulcer dyspepsia . -
pubmed
Results : We performed 30 ( 47 % ) uniportal thoracoscopic pleural decortication and 34 ( 53 % ) open decortication for
empyema in stage II ( 40 % ) or III ( 60 % ) obtaining a complete debridement and decortication in all
patients . -
pubmed
A large number of cellular and
animal models for
BTHS have been established to elucidate how
mitochondrial dysfunction induces sarcomere disorganization and reduced contractility , resulting in
dilated cardiomyopathy in vivo . -
pubmed
BACKGROUND :
Calciphylaxis is a serious complication in
patients with
chronic kidney disease associated
mineral and bone disorder . -
pubmed
So far , there are no definite diagnostic and therapeutic guidelines which may prevent the devastating outcome in many
calciphylaxis patients . -
pubmed
Based on this experience we discuss a systematic diagnostic and therapeutic approach in
patients with
calciphylaxis . -
pubmed
CASE PRESENTATION : We report a
patient with severe
calciphylaxis . -
pubmed
CONCLUSIONS : This case illustrates that laboratory tests can not reliably differentiate between high and
low bone turnover in
calciphylaxis patients . -
pubmed
METHODS : We studied 93
patients ( 8.0 % ) with locally advanced unresectable
pancreatic cancer without distant
metastases from among a total group of 1168
patients who were diagnosed with
pancreatic cancer from March 2005 to November 2015 at the Kochi Health Sciences Center , Kochi , Japan . -
pubmed
On the other hand , the overall 1- , 3- and 5 - year survival rates in
patients who were reclassified as having resectable
tumour after CRT were 71.3 % , 39.2 % and 23.5 % , respectively . -
pubmed
We aimed to examine the relationship between
HP infection and severity of
coronary atherosclerosis in
patients with chronic
CAD . -
pubmed
CONCLUSION : It is likely that
HP infection is not a risk factor for the severity of
coronary atherosclerosis in chronic
CAD patients . -
pubmed
STUDY OBJECTIVE : To evaluate the feasibility , safety , and outcome of laparoscopic modified Davydov vaginoplasty in
subjects with
partial androgen insensitivity syndrome (
PAIS ) . -
pubmed
CONCLUSION : This is the first study reporting the outcomes of laparoscopic modified Davydov vaginoplasty in
subjects with
PAIS . -
pubmed
Postoperative long - term outcomes were comparable with those achieved in
women with
Rokitansky syndrome . -
pubmed
BACKGROUND :
Hepatitis B virus (
HBV ) carriers worldwide number approximately 240 million people and around 780,000 people die every year from
HBV infection . -
pubmed
After hatching , 120 male
chicks with average
body weight ( BW ) were randomly allocated into each treatment group for a 7 - day feeding trial . -
pubmed
METHODS : This is a prospective , controlled , clinical study evaluating the impact of UV irradiation on the electrical impedance spectroscopy scores of
benign nevi in 50
patients undergoing phototherapy . -
pubmed
To this end ,
benign nevi of
patients with a medical indication for phototherapy will be measured by electrical impedance spectroscopy before , during and after UV irradiation . -
pubmed
MATERIALS AND METHODS :
Patients with
tinnitus presenting to our center retrospectively had their nerve size assessed by MRI . -
pubmed
Rapid
wound healing and subsequent formation of the apical epithelial cap ( AEC ) are believed to be required for successful appendage regeneration in
amphibians . -
pubmed
Methods : A total of 301
outpatients ( men , 116 ;
women , 185 ; mean age , 65 + - 11 years ) , with no history of
cardiovascular diseases , undergoing treatment for
diabetes mellitus were enrolled . -
pubmed
Early
brain injury (
EBI ) plays a key role in determining the prognosis of
patients suffering from
subarachnoid hemorrhage (
SAH ) . -
pubmed
Rats received intraperitoneal administration of
resveratrol or vehicle immediately after establishing
SAH model . -
pubmed
We found that mortality and
brain edema were significantly lower , whereas the neurological score was higher for
resveratrol - treated
rats . -
pubmed
HE staining showed that
resveratrol significantly reduced the
neuronal pyknosis and swelling in the
resveratrol - treated
rats compared with SAH
rats . -
pubmed
A major contributing factor associated with increased cardiac mortality in
patients with
schizophrenia (
SCZ ) seems to be a
dysfunction of the autonomic nervous system ( ANS ) . -
pubmed
Prospective trials aimed at examining the cardiovascular implications of acute
psychosis treatment in
patients with
schizophrenia are warranted . -
pubmed
METHODS The authors performed a prospective cohort study of
craniosynostosis patients ( n = 34 ) referred to a single national ( tertiary ) craniofacial unit . -
pubmed
Controls ( n = 28 ) consisted of
children who were referred to the unit 's outpatient clinic and did not have
craniosynostosis . -
pubmed
RESULTS Preoperatively , SSSv was decreased in
craniosynostosis patients compared with controls ( 7.57 vs 11.31 cm / sec , p = 0.009 ) . -
pubmed
Natalizumab is highly effective in the treatment of
relapsing multiple sclerosis patients . -
pubmed
Here we present a case of a
patient who experienced a dramatic course with severe
central nervous system inflammation after discontinuation of
natalizumab and treatment initiation with
daclizumab . -
pubmed
Atypical crusted
scabies in a patient with
chronic liver disease caused by
hepatitis B and
D viruses . -
pubmed
Crusted scabies is a less common variant of
scabies that is highly contagious , difficult to treat and involves infestation by
Sarcoptes scabiei var . - pubmed
Patients were invited to complete a questionnaire that included
pain and
anxiety using a visual analogue scale ( VAS ) following the testing . -
pubmed
CONCLUSION :
Patients transferred to a level - I
trauma center are generally more severely ill at the time of admission , but mortality and mean hospital stay are similar in directly admitted and transferred patients . -
pubmed
Plasmodium vivax readiness to transmit : implication for
malaria eradication . -
pubmed
BACKGROUND : The lack of a continuous long - term in vitro culture system for
Plasmodium vivax severely limits our knowledge of pathophysiology of the most widespread
malaria parasite . -
pubmed
vivax human
infections , we used Next Generation Sequencing data mining to unravel parasite in vivo expression profiles for
P. - pubmed
Patients with
ischemic heart disease are associated with poor prognosis , and their number has increased globally . -
pubmed
We have outlined and thoroughly reviewed in chronological order all of the interventions from birth to adulthood necessary in the comprehensive care of the
patient with
cleft lip and palate , along with the effects they may or may not have on facial growth . -
pubmed
Association of
brucellosis to abortions in
humans and domestic ruminants in Kagera ecosystem , Tanzania . -
pubmed
Among aborted cases , 4 women ( out of 9 ) , 2
cows ( out of 7 ) , 2
goats ( out of 26 ) and zero
sheep ( out of 11 ) were positive to
brucellosis . -
pubmed
Seropositivity to
brucellosis was similar in aborted and non - aborted cases in
humans ( p=0.08 ) and in ruminants p=0.2 ) . -
pubmed
Infections to
brucellosis were increased in exposed pregnant women ( OR=19 ; 95 % CI : 1.8 - 203 , p=0.01 ) and in
cattle ( OR=11 ; 95 % CI : 1.3 - 88 , p=0.02 ) . -
pubmed
Control of
brucellosis in animals is likely to reduce the threat of abortions in
humans . -
pubmed
Lassa virus (
LASV ) poses a significant public health problem within the regions of
Lassa fever endemicity in Western Africa . -
pubmed
The impact of
Lassa fever on
human health , together with the limited existing countermeasures , highlights the importance of developing effective vaccines against
LASV . -
pubmed
rLASV(IGR / S - S ) was highly attenuated in
guinea pigs , and a single subcutaneous low dose of the virus completely protected against otherwise lethal
infection with
LASV - WT . -
pubmed
IMPORTANCE
Lassa virus (
LASV ) , the causative agent of
Lassa fever , infects several hundred thousand people in Western Africa , resulting in many lethal
Lassa fever cases . -
pubmed
We analyzed electroencephalogram ( EEG ) data from thirty - nine
children ( twenty - three with , sixteen without
DLD ) aged 7.17 - 15.83 years acquired during an auditory picture - word matching paradigm . -
pubmed
Results : Sixty - seven
children aged 3 to 36 months with an initial diagnosis of
FWS were enrolled . -
pubmed
Discussion : We evaluated the characteristics and clinical courses of young
children with
FWS presenting at a community hospital and the treatment approaches utilized by physicians . -
pubmed
arabiensis to adjust their host - seeking behaviour to bite
humans despite bednet protection , accounting for the maintenance of high rates of mosquito infectivity and
malaria transmission . -
pubmed
Bacteraemia resulting from
respiratory infection was confirmed in two cases ( one each community - acquired
Klebsiella pneumoniae and ventilator - associated
Enterobacter cloacae ) . -
pubmed
A low yield of positive respiratory cultures was identified ;
Staphylococcus aureus was the most common respiratory pathogen isolated in community - acquired
coinfection ( 4/24 ; 16.7 % ) , with pseudomonas and
yeast identified in late - onset
infection . -
pubmed
Comparable rates of positive
coinfection were identified in the control group of confirmed
influenza infection ; clinically relevant
bacteraemias ( 2/141 ; 1.4 % ) , respiratory cultures ( 10/38 ; 26.3 % ) and
pneumococcal - positive antigens ( 1/19 ; 5.3 % ) were low . -
pubmed
(
Rosaceae ) , are usually recommended for the treatment of
uterine diseases . -
pubmed
(
Caprifoliaceae ) could alleviate the symptoms of
vulvovaginal candidiasis . -
pubmed
Eighteen to fifty - year - old
women with
vulvovaginal candidiasis were divided into the ' ward ' and placebo groups , 46 individuals in each group . -
pubmed
Results : Two weeks after medication administration , the
vaginal discharge sample of
patients was re - cultured ; 29
patients ( 63.045 % ) in the ' ward ' group and 6 ( 13.04 % )
patients in the placebo group had negative culture ( p < 0.001 ) . -
pubmed
This finding has prompted us to explore whether such a phenomenon also occurs in
diabetic obese patients . -
pubmed
RESULTS : Despite subtle modifications in the oral microbiota composition , comparison of orosensory lipid perception in controls and
diabetic subjects did not lead to discriminating data due to the large inter -
individual variability of
linoleic acid perception thresholds . -
pubmed
CONCLUSIONS : Collectively , these data show that the
diabetic patients with defective fatty taste detection are characterized by a specific microbiota metabolism at the circumvallate papillae levels , this occurrence seeming amplified by drugs commonly used to counteract the damaging metabolic effects of
T2D. -
pubmed
Accurate staging and treatment planning are imperative for precise management in
Anal Cancer ( ACa )
patients . -
pubmed
Background : Women living with
human immunodeficiency virus (
HIV ) are more likely to develop an increased risk of invasive
cervical cancer . -
pubmed
A case of
Schonlein - Henoch purpura induced by immune checkpoint inhibitor in a
patient with
metastatic melanoma . -
pubmed
acidophilus ) KBL402 and KBL409 treatment in the alleviation of
colitis using the in vivo dextran
sodium sulfate ( DSS)-induced
colitis mice model . -
pubmed
Various
colitis symptoms of
mice , including disease activity index score [ 4.55 + - 0.99 ( P < 0.001 ) and 5.12 + - 0.94 ( P < 0.001 ) , respectively ] , colon length [ 6.18 + - 0.43 mm ( P < 0.001 ) and 6.62 + - 0.47 mm ( P < 0.001 ) , respectively ] , and colon histological score [ ( 5.33 + - 1.03 ( P < 0.001 ) and 4.00 + - 0.89 ( P < 0.01 ) , respectively ) ] , were significantly restored with
L. - pubmed
Expressions of
inflammation - related micro - RNAs ( miRs ) were also significantly altered in
mice with
L. - pubmed
Comparisons of antidotal efficacy of
sodium diethyldithiocarbamate ,
D - penicillamine and
triethylenetetramine upon acute
toxicity of
nickel carbonyl in
rats . -
pubmed
Sodium diethyldithiocarbamate ,
D - penicillamine , and
triethylene - tetramine were administered to
rats by i m injection in dosages equivalent to 0.6 times their respective LD50 values in order to compare their relative effectiveness in prevention of
death caused by exposure for 15 min to inhalation of
nickel carbonyl ( 1.4 or 4.2 mg
Ni ( CO ) 4 / liter of air ) . -
pubmed
The application of positive end - expiratory pressure ( PEEP ) as part of artificial ventilation is currently considered a basic provision to provide adequate treatment of
critically ill patients in intensive care units . -
pubmed
The meiotic effect of a deficiency in
Drosophila melanogaster with a model for the effects of
enzyme deficiency on recombination . -
pubmed
At the follow - up catheterization , 39 ( 41 % ) of the
patients were in improved condition and 56 patients ( 59 % ) had
recurrence of symptoms , allowing for analysis of the effect of the procedure in two symptomatic
patient subsets . -
pubmed
The preoperative use of endoscopic ultrasound was evaluated in 74
patients with confirmed
gastric cancer . -
pubmed
The success rate in detecting lymph node
metastasis was 50 % ( 11 of 22
patients ) ; the accuracy in diagnosing direct infiltration to the adjacent organs was 60 % ( three of five
patients ) . -
pubmed
A significantly lower enzymatic activity was found in atrial specimens from
patients with
left ventricular heart failure in comparison to the atrial fragments obtained from the
patients with normal heart function . -
pubmed
Verapamil enhanced in vitro chemosensitivity of a
murine bladder carcinoma , FCB . -
pubmed
The in vitro enhancement of chemotherapeutic efficacy by
verapamil , a
calcium antagonist , was assessed using FCB , a transplantable
murine transitional cell carcinoma . -
pubmed
Our study indicates that the use of
verapamil in combination with cytotoxic agents for intravesical chemotherapy of
bladder tumors may prove to be beneficial in
human patients . -
pubmed
The highest catalytic concentrations of the enzyme were observed in the synovial fluids of
patients suffering from
rheumatoid arthritis ( median value : 5.56 mU / l , 90%-range : 3.2 - 22.0 mU / l ) . -
pubmed
Synovial fluids of
patients with
arthritis urica , however , showing a comparable high degree of
inflammation , contained lower enzyme catalytic concentrations ( median value : 2.38 mU / l , 90%-range : 0.7 - 5.2 mU / l ) , which were in the range of those in
osteoarthrosis ( median value : 2.50 mU / l , 90%-range : 0.8 - 4.8 mU / l ) . -
pubmed
Comparison of in vitro cloning assays for drug sensitivity testing of
human brain tumours . -
pubmed
The
MK-0787 /
MK-0791 was used in 8 female
patients with
intrapelvic infections . -
pubmed
Treatment of
xerostomia in
patients with primary
Sjogren ' s syndrome with sulfarlem . -
pubmed
Stimulated by a recent report on the favorable effect of
Anetholtritione (
Sulfarlem S 25 ) on symptoms and salivary flow rate in
patients with
Sjogren ' s Syndrome (
SS ) , we examined the effect of
Sulfarlem in an open study on 16
patients characterized by severe
xerostomia . -
pubmed
At the same time the
patients assessed their symptoms of
xerostomia on a 1 - 10 visual analogue scale . -
pubmed
Side effects were
abdominal discomfort and
flatulence , seen in 7
patients ( 44 % ) . -
pubmed
One of these
patients in addition had
diarrhea and
nausea . -
pubmed
It is concluded that
Sulfarlem in a daily dose of 75 mg have no marked effect on
salivation in
patients with primary
SS and severe
xerostomia . -
pubmed
In order to contribute to the knowledge and the nosography of
fibroblastic rheumatism , the authors report a case occurring in 68 years old
patient . -
pubmed
Neurologic complications were noted in 4 % and
pneumonia in 14 % of the hospitalized
patients . -
pubmed
Fatal outcomes were reported in 3
children ( 0.1 % ) , 2 of whom had severe
congenital disabilities . -
pubmed
Thirteen complications developed following one - stage lengthening of the femur , which included significant loss of length in five
patients ,
femoral nerve palsies in four
patients , three
deep infections , and one
nonunion . -
pubmed
Transplantation of spontaneous
hepatomas in
C3H mice ; biological and biochemical studies . -
pubmed
Twenty uncomplicated pregnancies , 10
parturients with mild and 10 parturients with severe
pre - eclampsia , all with uncomplicated deliveries , were studied . -
pubmed
)-induced
bronchoconstriction in anaesthetized
rats . -
pubmed
coli
strains is different than that in
S. - pubmed
The decline in plasma
calcium was greater in
patients with
osteomalacia at 90 ( P less than 0.05 ) , 120 ( P less than 0.01 ) , and 150 min ( P less than 0.01 ) . -
pubmed
In
osteomalacia patients the surface density of histologically detectable trabecular bone
aluminum correlated directly with the percent relative osteoid volume ( P less than 0.005 ) and inversely with the maximum amino terminal
parathyroid hormone response to
hypocalcemia ( P less than 0.025 ) . -
pubmed
These results suggest that hemodialysis
patients with
osteomalacia have diminished secretion of
parathyroid hormone and a decreased ability to restore plasma
calcium homeostasis during
hypocalcemia . -
pubmed
Additionally , antibody produced in response to a
formalin - heat inactivated preparation was capable of reacting with antigen determinants present on the cell surface of several heterologous
strains of
V. - pubmed
We still need to evaluate
dysphagia in
patients with
lymphoma by standard means , despite reports of " secondary "
achalasia . -
pubmed
Ultrastructural investigations of the blood vessels of thyroid in experimental acute
anaphylactic shock in
guinea pigs . -
pubmed
Three
patients with
anencephalic fetuses were delivered vaginally following use of
prostaglandin E2 (
PGE2 ) vaginal suppositories with minimal side effects and minimal delay until delivery , even though the cervix was unfavorable . -
pubmed
The antiarrhythmic effects of
amiodarone hydrochloride and
flecainide acetate in
patients with resistant chronic
AF have been investigated separately in several small studies . -
pubmed
This investigation compared
amiodarone to
flecainide in maintaining NSR in
patients with resistant chronic
AF . -
pubmed
METHODS : Studies using
amiodarone or
flecainide in the treatment of
patients with chronic
AF refractory to class I antiarrhythmic drugs or
sotalol hydrochloride were identified . -
pubmed
The percentages of
patients taking
amiodarone or
flecainide and remaining in NSR at 3 and 12 months were compared relative to results for
quinidine , which were acquired from a meta - analysis of
quinidine used as first - line therapy for
AF . -
pubmed
Pituitary - gonadal dysfunction in male
patients with
lung cancer . -
pubmed
Male lung cancer patients with poor performance status have an
endocrinological dysfunction shown by decreased serum levels of total and free
testosterone ( AFTC ) . -
pubmed
Twenty - seven
patients with locally advanced
non - small cell lung cancer were included . -
pubmed
Review of 20
patients with
glucocorticoid deficiency ( three cases also with
salt loss ) associated with absent tear secretion ( 19 cases ) and
achalasia of the cardia ( 15 cases ) revealed
neurological abnormalities in 17 including
hyper - reflexia ,
muscle weakness ,
dysarthria , and
ataxia together with
impaired intelligence and
abnormal autonomic function , particularly
postural hypotension . -
pubmed
Danazol , 10 mg / kg / day ( maximum 600 mg / day ) was given in two divided doses for 14 days in 30
patients with
haemophilia - A. -
pubmed
Thus ,
lung injury after the development of tolerance to
phosgene provides a unique
animal model of a
respiratory distress syndrome in which neutrophils are not associated with
injury but rather with a protective effect . -
pubmed
We are reporting the case of a 94 - year - old male
patient with a 10 - year history of
Parkinson ' s disease , who was admitted to our hospital with acute obstruction of esophageal passage . -
pubmed
While
dysphagia is commonly encountered in
patients with
Parkinson ' s disease , the observed succession of drug discontinuation and resolution of obstruction in this case suggests an as yet rarely described side effect of
levodopa . -
pubmed
This potential side effect should be included in the differential diagnosis of
dysphagia in
Parkinson ' s disease , especially in the case of older
patients , who may exhibit an increased rate of intestinal absorption of
levodopa . -
pubmed
,
tumor - free
mice / total
mice = 14 of 15 ( 93 % ) for
Meth A and 7 of 15 ( 47 % ) for
hepatoma MH134 . -
pubmed
In this study the tilt test , in combination with
isoproterenol administration , was used to investigate 44
patients with unexplained
syncope . -
pubmed
Treatment of three
patients with
systemic mastocytosis with
interferon alpha-2b . -
pubmed
It has been reported that the administration of
interferon alpha-2b is of potential benefit in the treatment of
mastocytosis based on a single
patient study ( NEJM , Feb 27 , 1992 , 326(9):619 - 623 ) . -
pubmed
Following this report , we administered
interferon alpha-2b at a dose of 4 to 5 million units per square meter of body surface area for at least 12 months to one
patient with
mastocytosis with an associated
hematologic disorder (
patient 1 ) , one
patient with aggressive
systemic mastocytosis (
patient 2 ) , and one
patient with indolent
mastocytosis (
patient 3 ) . -
pubmed
Thus , in our study of three
patients with
systemic mastocytosis , treatment with
interferon alpha-2b was found to be ineffective in controlling progression of disease . -
pubmed
While treatment with supplemental
oxygen is often essential in
patients with
lung disease , prolonged therapy may cause
lung injury by itself . -
pubmed
METHODS : Four
patients ( two each with an endocrine
tumor and a
cystic lesion ) underwent the procedure . -
pubmed
We also performed the spleen - preserving Puestow 's procedure with removal of the tail of the pancreas in a 22 - year - old male
patient with
familial chronic pancreatitis . -
pubmed
A
pancreatic fistula remained in one
patient for several weeks . -
pubmed
An 86 - year - old
woman was admitted to our hospital with
genitourinary bleeding . -
pubmed
Since the initial gene - transfer clinical trial in 1989 , over 300
cancer patients have been enrolled in gene therapy trials . -
pubmed
Terminal deficiencies (
TDs ) generated by the r - X1 deletion system in
maize were used to physically map RFLP markers on the short arm of chromosome 2 ( 2S ) and the long arm of chromosome 6 ( 6L ) , chromosome 8 ( 8L ) , and chromosome 10 ( 10L ) . -
pubmed
METHODS : A 10 - ml blood sample and six colonic biopsy specimens were obtained from 24
patients with either active
ulcerative colitis or in remission and 10
patients with
irritable bowel syndrome for measurement of trace elements and trace element - dependent enzymes . -
pubmed
CONCLUSIONS :
Patients with
ulcerative colitis have altered plasma and tissue levels of trace elements and antioxidant - related enzymes . -
pubmed
CONCLUSION : Differences in the mean value and in the 95 % normal range of standardized volumes of the hippocampal formation , the amygdala , and the temporal horn correspond to differences in age among healthy subjects ; therefore , age should be considered a factor in correlative research , especially in that involving
patients in the early stages of
Alzheimer disease . -
pubmed
Helicobacter pylori leads to a
chronic infection in
humans that is associated with
gastric inflammation and a vigorous immune response . -
pubmed
Despite the humoral and cellular responses that can be detected in both
human and animal models of
helicobacter infection , the immune response fails to eliminate the organism . -
pubmed
Results of vaccine studies in
mouse models indicate that modulating the helper T cell response from a T helper cell type 1 to a T helper cell type 2 response likely is required for the prevention and elimination of
helicobacter infection . -
pubmed
Understanding the mechanisms by which the immune response controls
bacterial infections will allow for the design of novel strategies of immune modulation and the development of vaccines for both the treatment and prevention of
H pylori . -
pubmed
In mature
animals axons can regenerate satisfactorily through the endoneurial tubes of the root but cease growth on reaching the
gliotic tissue . -
pubmed
Implications for the development of
human congenital heart defects are discussed . -
pubmed
BACKGROUND : Minimizing the number and scope of ports used to perform laparoscopic cholecystectomy attempts to build on the improvements in postoperative
pain control , rapid return to activity and work ,
patient satisfaction , and cosmetic result achieved by the laparoscopic method . -
pubmed
A statistically significant difference was found in
incisional pain between the smaller group ( 21
patients ) with two 10 - mm ports and one 5 - mm port and the larger group ( 100
patients ) with three 5 - mm ports , whether the measure was overall
incisional pain ( p = 0.014 ) or a comparison based on specific ports ( p = 0.001 ) . -
pubmed
The first
patient developed
muscle hypertonicity ,
jerky movements and
unconsciousness after an uneventful anaesthesia with
propofol , and later the same thing happened after anaesthesia with
thiopentone . -
pubmed
Photodynamic therapy with topical
aminolevulinic acid was tested for the treatment of
acne vulgaris , in an open - label prospective
human study . -
pubmed
Each of 22
subjects with
acne on the back was treated in four sites with
aminolevulinic acid plus red light ,
aminolevulinic acid alone , light alone , and untreated control . -
pubmed
Potentially ,
aminolevulinic acid plus red light may be useful for some
patients with
acne . -
pubmed
The tests were performed in 16
patients ( mean age 40.6 + /- 10.8 SD years , 10
men , 6
women ) during operative correction of their
incisional hernias in the anterior abdominal wall . -
pubmed
Generalized epilepsy with
febrile seizures plus (
GEFS+ ) is a benign
epileptic syndrome of
humans . -
pubmed
The use of
omeprazole to alleviate
stomach ulcers in
swine during periods of feed withdrawal . -
pubmed
Fasting for 24 h or for 48 h , resulted in more
pigs developing
ulcers ( 15 of 25 ) than
pigs allowed free access to feed ( 1 out of 10 ) ( P = 0.01 ) . -
pubmed
The presentations were ( 1 ) Sex differences in
ethanol pharmacokinetics , by E. Baraona ; ( 2 )
Estrogen regulates the sensitivity to endotoxin in hepatic Kupffer cells , by K. Ikejima ; ( 3 ) Sex difference in
alcohol - related
organ injury , by E. Mezey ; ( 4 ) Aggravated
ethanol - induced
liver injury in female
rats : Protection by the antiestrogen
toremifene , by Harri A. Jarvelainen ; and ( 5 )
Alcohol metabolism in
Asian subjects : Sex differences and flushing response , by V. A. Ramchandani . -
pubmed
METHODS : Short term effects of nebulised
adrenaline and saline placebo were compared in
infants with moderately severe acute
bronchiolitis . -
pubmed
Giardia lamblia is a flagellated protozoan that infects several species including
humans and is a major agent of waterborne outbreaks of
diarrhea . -
pubmed
Transgenic females only developed
mammary cancer if treated with
androgens . -
pubmed
Siggaard - Andersen 's comprehensive classification of tissue
hypoxia can be used as an integrative model to build coherent algorithms for diagnosing and managing neurocritical
patients that are at risk of
brain hypoxia due to either intracranial or extracranial conditions . -
pubmed
Effects of
morphine analgesia on diagnostic accuracy in Emergency Department
patients with
abdominal pain : a prospective , randomized trial . -
pubmed
BACKGROUND : Because of concerns about masking important physical findings , there is controversy surrounding whether it is safe to provide analgesia to
patients with undifferentiated
abdominal pain . -
pubmed
The purpose of this study was to address the effects of analgesia on the physical examination and diagnostic accuracy for
patients with
abdominal pain . -
pubmed
MS patients were no more likely than controls to have a change in
pain location ( 34.0 % versus 41.2 % , RR 0.82 , 95 % CI 0.50 - 1.36 ) . -
pubmed
CONCLUSIONS : Results of this study support a practice of early provision of analgesia to
patients with undifferentiated
abdominal pain . -
pubmed
Here we show that
Cerebrolysin , an anti -
dementia drug that improves the activity of daily living of
Alzheimer disease (
AD )
patients , can enhance neurogenesis and spatial learning of adult female
rats . -
pubmed
BACKGROUND AND PURPOSE : The fetus is well known to be able to survive prolonged exposure to
asphyxia with minimal
injury compared with older
animals . -
pubmed
Recurrence or persistence of
varicose veins after treatment may be charged to incomplete original evaluation of the
patients '
venous insufficiency and to therapy that was not adequate because not planned on the basis of the particular kind or degree of
venous incompetence in each individual case . -
pubmed
METHODS : Twelve Bosnian war
refugees with
PTSD and 13 control
subjects were studied . -
pubmed
RESULTS : The
PTSD patients showed no
cortisol response after awakening and had lower daytime
cortisol levels ( F = 14.57 , p & lt;.001 ) . -
pubmed
OBJECTIVE AND METHODS : To study the effects of hormone replacement therapy on
glucose metabolism , 31
obese (
body mass index & gt ; or = 27 kg / m(2 ) ) postmenopausal
women were randomized to treatment with
tibolone ( 2.5 mg once daily ; TIB ; n=16 ) or to
oestradiol valerate ( 2 mg daily)-
dydrogesterone ( 20 mg daily for 2 weeks every 3 months ; ED ; n=15 ) for 12 months . -
pubmed
METHODS : Subjective sleep reports and sleep habit assessments were obtained from 25
adolescents with functional
RAP and from 15 age- and gender - matched healthy volunteers , and were compared with continuous movement monitoring using the Actigraph for 7 consecutive days . -
pubmed
Development of a protective index to rank effectiveness of multiple treatments within an experiment : application to a cross - protection study of several
strains of
Eimeria maxima and a live vaccine . -
pubmed
Vaccination of
chickens with live oocysts has become a more widely used method for controlling avian
coccidiosis as resistance to anticoccidial medication increases . -
pubmed
To confirm that rtEa4 - peptide can exhibit the same spectrum of antitumor activities in
fish tumor cells , we had developed permanent single - cell clones (
RTH1B1A ,
RTH1B1D ,
RTH1B2A , and
RTH1B2C ) from a
rainbow trout liver tumor induced by
dibenzo [ a , l ] pyrene treatment . -
pubmed
CONCLUSIONS :
PTS increased significantly in
infants with
MUL , mainly at week 2 of postnatal life , persisting high until term CA , and correlated with other abnormal EEG findings . -
pubmed
During
tetanic stimulation at 100 Hz the transient amplitude decays to 20 % in toad fibres and 40 % in
mouse fibres . -
pubmed
Bacterial
infections that can be transmitted by sexual contact are usually caused by the following organisms :
Neisseria gonorrhoeae ,
Chlamydia trachomatis ,
Treponema pallidum and
Klebsiella granulomatis . -
pubmed
CONCLUSION : Our results support the hypothesis that once - weekly oral
morphine can reduce symptoms in some treatment - resistant
OCD patients . -
pubmed
Summary
Mice homozygous for an inactivation of the interleukin-2 ( IL-2 ) gene develop a
T - cell dependent colitis . -
pubmed
Despite the progress made modeling
MSA neuropathology in the transgenic
mouse models , the molecular mechanism of how alphaSYN aggregation in oligodendrocytes causes neurodegeneration remains to be established . -
pubmed
MATERIAL AND METHODS : A retrospective cohort study included 63
adults ( 40
males and 23
females ) with diagnosed
brain tumors treated during 2001 and 2002 at the Department of Neurology in Novi Sad . -
pubmed
Multiple
metastases were estimated in 56 % of
patients and solitary
tumors in 44 % , without statistical significance ( 2 = 0.48 ; p & gt ; 0.05 ) . -
pubmed
Acute and chronic
estradiol treatments reduce
memory deficits induced by transient global
ischemia in female
rats . -
pubmed
We investigated whether long - term
estradiol ( 21 - day pellets implanted 14 days prior to
ischemia ) or acute
estradiol ( 50 microg infused into the lateral ventricles immediately after
ischemia ) attenuates
ischemia - induced cell loss and improves visual and spatial working memory in ovariectomized female
rats . -
pubmed
Quadrigeminal cistern arachnoid cyst in a
patient with
Kabuki syndrome . -
pubmed
Statin therapy for
patients with chronic
heart failure . -
pubmed
METHODS :
Neurosteroid levels (
allopregnanolone ,
pregnenolone ,
dehydroepiandrosterone [
DHEA ] ) were determined in postmortem PFC in 14 male
subjects with
AD and 15 cognitively intact male control
subjects by gas chromatography / mass spectrometry preceded by high - performance liquid chromatography purification . -
pubmed
RESULTS :
Subjects with
AD exhibit significant reductions in
allopregnanolone compared with cognitively intact control
subjects ( median levels = 2.50 ng / g vs. 5.59 ng / g , respectively ; p = .02 ) . -
pubmed
Median
DHEA levels are elevated in
subjects with
AD ( p = .01 ) . -
pubmed
CONCLUSIONS :
Subjects with
AD demonstrate significant reductions in PFC
allopregnanolone levels , a finding that may be relevant to neuropathological disease stage severity . -
pubmed
This
strain can grow at 50 degrees C but not at 51 degrees C , a temperature at which wild - type
B. - pubmed
Pravastatin enhances beneficial effects of
olmesartan on
vascular injury of salt - sensitive
hypertensive rats , via pleiotropic effects . -
pubmed
RESULTS : The modified ALTK procedure effectively treated a
patient with moderate
keratoconus with a best - corrected visual acuity of 20/80 , despite rigid gas - permeable contact lenses . -
pubmed
This report describes a 76 - year - old female
patient with
pseudomyxoma peritonei who presented with lower
abdominal pain and bilateral femoral masses . -
pubmed
HHV-8 DNA was detected in 14 of the 17
Kaposi ' s sarcoma tissue samples and both of the
primary effusion lymphoma cell lines . -
pubmed
Low - level laser therapy for zymosan - induced
arthritis in
rats : Importance of illumination time . -
pubmed
METHODS : We tested LLLT on
rats that had zymosan injected into their knee joints to induce
inflammatory arthritis . -
pubmed
The availability of a simple , sensitive , and rapid test using whole blood to facilitate processing and to reduce the turnaround time could improve the management of
patients presenting with
chest pain . -
pubmed
High tobacco use among the less educated and under privileged affects them in multiple ways : ( i ) Tobacco users in such households , because of their
nicotine addiction , prefer spending a disproportionate amount of their meager income on
tobacco products , often curtailing essential expenditures for food , healthcare and education for the family . -
pubmed
( iii )
Premature death caused by
tobacco use in this under- privileged section often takes away the major wage earner in the family , plunging it into even more hardship . -
pubmed
Tobacco use , education and health in a
human population are inter - related in ways that make sufferings and
deaths caused by
tobacco use even more tragic than normally realized . -
pubmed
The seasonality of
human cryptosporidiosis in New Zealand . -
pubmed
While consensus and guidelines on therapeutic management in infancy and childhood are available , data regarding the treatment of
adults with
CAH are scarce . -
pubmed
This review highlights the issues that need to be addressed when caring for the adult
CAH patient . -
pubmed
Use of the
folinic acid/
5 - fluorouracil /
irinotecan ( FOLFIRI 1 ) regimen in elderly
patients as a first - line treatment for metastatic
colorectal cancer : a Phase II study . -
pubmed
BACKGROUND : The aim of this study was to evaluate the effects of a combination of
folinic acid ,
5 - fluorouracil (
5FU ) and
irinotecan ( FOLFIRI 1 ) administered every 2 weeks in a population of elderly
subjects with advanced
colorectal cancer . -
pubmed
PATIENTS AND METHODS :
Patients with metastatic
colorectal cancer included in this study were aged at least 70 years , with a performance status of 0/1 , without
geriatric syndrome and without previous palliative chemotherapy . -
pubmed
All
PHPT patients became normocalcaemic following successful neck exploration . -
pubmed
OBJECTIVE :
Patients on
buprenorphine maintenance for
opioid dependence often abuse its additional doses over and above the maintenance dose . -
pubmed
DESIGN AND SETTING : This was an interventional study , carried out in an in -
patient setting in a tertiary care national
drug dependence treatment center . -
pubmed
[ Initiation modes of spontaneous monomorphic
ventricular tachycardia in
patients with
Chagas heart disease ] . -
pubmed
INTRODUCTION AND OBJECTIVES : We sought to demonstrate the mode of spontaneous onset of sustained monomorphic
ventricular tachycardia in
patients with
Chagas ' cardiomyopathy . -
pubmed
METHODS : We studied 222 stored electrograms in 14
patients with
Chagas cardiomyopathy and spontaneous monomorphic
ventricular tachycardia treated with a cardioverter defibrillator . -
pubmed
Production of
nicotinic acid from
Saccharomyces cerevisiae in exponential growth on
glucose was found to be growth associated , and in the stationary and decline phase was found to be
death associated . -
pubmed
Primary cultures of
human urothelial cells for
genotoxicity testing . -
pubmed
Cell cultures of primary
human urothelial cells may be used for in vitro testing of cytotoxic or
genotoxic effects . -
pubmed
Our results are in line with functional imaging studies in
patients with
schizophrenia , which also showed a differential activation in lateral prefrontal areas . -
pubmed
However , at surgery , with a 125 - microg dose , these
patients had a discontinuous layer of vitreous present on the retinal surface resulting from the induction of an anomalous
PVD in the form of
vitreoschisis . -
pubmed
METHODS : Twenty - five
patients with primary or secondary
open - angle glaucoma and at high risk for postoperative
cicatrization underwent deep sclerectomy and were randomly distributed to the two treatment arms . -
pubmed
METHODS :
Patients with
anastomotic leakage after abdominothoracic oesophagectomy treated by endoscopic insertion of self - expanding plastic stents between 2001 and 2007 were studied . -
pubmed
These
mice displayed no
tooth eruption or tooth root formation . -
pubmed
Adult mutant
mice developed
odontoma - like proliferations near the proximal ends of the incisors . -
pubmed
CLINICAL RELEVANCE : These data suggest that cerebral magnetic resonance imaging may be recommended in the clinical treatment of
patients with apparently isolated
ARA , even when neurological symptoms or signs are lacking . -
pubmed
MATERIAL / METHODS : Fresh tissue samples were obtained from 28
patients ( ages 26 to 81 years ) with primary colorectal
adenocarcinoma and corresponding
normal tissues . -
pubmed
Visuospatial working memory deficits in remitted
patients with
bipolar disorder : susceptibility to the effects of GABAergic agonists . -
pubmed
METHODS : A total of 32 remitted
BPD patients and 39 healthy controls undertook parametric VSWM tasks and assessments for selective attention , sustained attention , psychomotor speed , mental flexibility , and Wechsler Adult Intelligence Scale - III full IQ . -
pubmed
RESULTS : Remitted
BPD patients showed more pronounced performance declines in VSWM performances as WM loads increased , indicating inefficient VSWM processing . -
pubmed
CONCLUSIONS : Remitted
BPD patients had WM - load - dependent VSWM processing deficits after controlling for neurocognitive performances . -
pubmed
Prophylaxis of
embolic events with
idraparinux over an 18 - month period in
patients with
atrial fibrillation was as effective as international normalized ratio - adjusted
warfarin but induced more major
bleeding complications . -
pubmed
Currently
idrabiotaparinux once weekly 3.5 mg subcutaneous is being investigated in clinical trials for the prevention of recurrent events in
patients with acute
VTE and
atrial fibrillation . -
pubmed
Computed tomographic pulmonary angiography for diagnosis of
invasive mold diseases in
patients with
hematological malignancies . -
pubmed
BACKGROUND :
Invasive mold diseases (
IMDs ) of the lung remain a challenge for immunocompromised
patients . -
pubmed
METHODS : To explore the diagnostic utility of computed tomographic pulmonary angiography ( CTPA ) for detecting angioinvasive patterns of
pulmonary infection , we performed a single - center , prospective , nonrandomized trial involving 36
patients with
hematological malignancies who had clinical suspicion of
IMD , as defined by European Organization for Research and Treatment of
Cancer /
Mycosis Study Group diagnostic criteria . -
pubmed
In 15 of 24 patients with a final diagnosis of possible
IMD , CTPA findings were negative for 14
patients and were positive for 1
patient , who had septic
emboli associated with
Staphylococcus aureus bacteremia . -
pubmed
CONCLUSIONS : We conclude that CTPA appears to be a promising tool to exclude the diagnosis of
IMD in high - risk
patients without specific findings on HRCT scans , and it is most useful in the presence of well - circumscribed lesions in which there is suspicion for
IMD . -
pubmed
Our results show the key role of immune subversion in effective
human infection by small bacterial populations . -
pubmed
Nonconvulsive status epilepticus : the
encephalopathic pediatric
patient . -
pubmed
Recent prospective pediatric studies focus on
critically ill children and show wide variability in the frequency of
NCSE . -
pubmed
METHODS : Medical records from
patients aged 3 months to 21 years were identified either by ( 1 ) searching a clinical EEG database ( n = 18 ) or ( 2 ) consecutive inpatient EEG referrals for
NCSE over an 8 - month period ( n = 57 ) . -
pubmed
NCSE was identified in 26
patients ( 35 % ) and in 8 of 57 ( 14 % )
patients referred for possible
NCSE . -
pubmed
A witnessed clinical
seizure was observed in 24 of 26 ( 92 % )
patients with
NCSE . -
pubmed
Acute cortical neuroimaging abnormalities were significantly more frequent in
patients with
NCSE . -
pubmed
All but 1
patient with
NCSE had electrographic or electroclinical
seizures within the first hour of monitoring . -
pubmed
Children with acute
encephalopathy should undergo continuous EEG . -
pubmed
We present a case in which a
patient was treated with covered stent implantation for acute
bleeding from the superior mesenteric artery following pancreatic resection , radiation , and embolization of a
hepatic artery pseudoaneurysm . -
pubmed
Effect of
patient sex on white matter alterations in unilateral
medial temporal lobe epilepsy with
hippocampal sclerosis assessed by diffusion tensor imaging . -
pubmed
BACKGROUND AND PURPOSE : Studies shows ictal behavior and symptoms are affected by
patient sex in
temporal lobe epilepsy . -
pubmed
The purpose of our study was to determine whether alterations in the WM as assessed by DTI display different patterns in male and female
patients with unilateral
HS . -
pubmed
MATERIALS AND METHODS :
Patients with unilateral
HS were categorized as
women with right HS ( n=12 ) ,
men with right
HS ( n=10 ) ,
women with left
HS ( n=12 ) , and men with left
HS ( n=10 ) . -
pubmed
In
patients with right
HS , the ipsilateral cingulum , uncinate fasciculus , internal and external capsules , and right acoustic radiation were involved extensively in women . -
pubmed
BACKGROUND :
Moniliophthora perniciosa ( Stahel ) Aime & amp ; Phillips - Mora is the causal agent of
witches ' broom disease (
WBD ) in
cacao (
Theobroma cacao ) . -
pubmed
Injury of the CA1 subregion induced by a single injection of
kainic acid ( 1 x KA ) in juvenile
animals ( P20 ) is attenuated in
animals with two prior sustained neonatal
seizures on P6 and P9 . -
pubmed
CONCLUSION : Scanning of stomach specimens using electron microscope revealed that the
mice treated with standard and synthetic derivatives had no
injury observed in stomach mucosa , which is identical to that of the control
animal . -
pubmed
Neural pathway interference by retained acupuncture : a functional MRI study of a
dog model of
Parkinson ' s disease . -
pubmed
RESULTS AND DISCUSSION : Standard veterinary neurological examination was performed on
dogs with
MPTP - induced
PD . -
pubmed
A homogeneous grade similar to
human PD patients was evident in all
dogs . -
pubmed
The study provides evidence of the potential clinical applications of retained acupuncture at ST 36 for rehabilitation therapy of
PD patients . -
pubmed
Here , we report a rare presentation of metastatic
breast cancer patient with
bone marrow metastases , who was successfully treated with
trastuzumab combined chemotherapy . -
pubmed
Physicians should be careful in treating
bone marrow metastases in
breast cancer , since
patients can show improved marrow function after chemotherapy and long - lasting survival is possible . -
pubmed
The pathogenesis of
dengue virus infection remains poorly understood , mainly due to the lack of a suitable animal model that can recapitulate the cardinal features of
human dengue diseases . -
pubmed
There are four
dengue viral serotypes and each one of them is capable of causing severe
dengue . -
pubmed
We treated 60
patients with unilateral
ulnar neuropathy at the elbow , employing both techniques . -
pubmed
Six months postoperative we found no differences in treatment effect on
pain and disability scores between both groups , but both techniques resulted in an early postoperative relief of symptoms and good
patient satisfaction . -
pubmed
Considering the zoonotic potential of
tick - borne disease (
TBD ) agents and the fact that dogs may act as sentinels for
human infection , the aim of the present study was to determine the seroprevalence of
TBD agents and risk factors for exposure in two different canine populations from Parana State , Southern Brazil . -
pubmed
Dogs from UA showed a higher percentage of
tick infestation ( p = 0.0135 ) and were highly associated with seropositivity to
E. - pubmed
The proton beam radiosurgery was performed to 65
patients with
brain AVM since December , 2001 till February , 2012 , in Joint Institute for Nuclear Research , Dubna , Russia . -
pubmed
The radiosurgery was resulted in full obliteration of
AVM in 23 from remaining 46 ( 50 % )
patients . -
pubmed
There was full obliteration in 46.6 % of
patients with volume of AVM 10 - 24.9 cc ; and this rate is significantly more than for photon radiosurgery of same size
brain AVM . -
pubmed
Only one
patients suffered
hemorrhage from partially obliterated
AVM . -
pubmed
There were delayed radiation
toxicity in 5
patients in 12 months after treatment : in 4
patients , these reactions were assessed as 2 according to RTOG scale and were dissipated in 1 month after commencement of
corticosteroid treatment . -
pubmed
There was radiation
necrosis in one
patient , and it was relieved in 12 months after several courses of
dehydration and
corticosteroid therapy . -
pubmed
Specific disruption of hippocampal mossy fiber synapses in a
mouse model of
familial Alzheimer ' s disease . -
pubmed
Inhaled particles and gases ( in particular
tobacco smoke ) induce chronic
inflammation of the airways accompanied by a not fully reversible airflow limitation . -
pubmed
OBJECTIVE : To examine differences in
disease progression and nature of
tumor invasion that may lead to more accurate expectations of
tumor behavior and improved management options for plasmacytoid variant ( PCV ) histology
urothelial bladder cancer patients . -
pubmed
Carcinoma in situ on the luminal margin was noted for all cases , except in 5 of the 8 PCV
patients with + UM , in whom retrograde longitudinal invasion along the subserosal and adventitia was noted . -
pubmed
Remove isolated
vomiting as an automatic indication for computed tomography in
children with
head injury . -
pubmed
Unexpectedly , the Ex3 - del+/-
mice are not susceptible to
CPVT . -
pubmed
Model to predict the survival benefit of radiation for
patients with
rhabdomyosarcoma after surgery : a population - based study . -
pubmed
Patients with resection of
rhabdomyosarcoma between 1990 and 2010 were derived from the Surveillance , Epidemiology and End Results database . -
pubmed
CONCLUSION : The available literature sources do n't show that hormone replacement therapy for premenopausal
women worsens the prognosis of the underlying disease after treatment of
gynecological cancer . -
pubmed
Other complications included a permanent
neurologic deficit in 1
patient ( 5 % ) , transient
paraplegia in 4
patients ( 20 % ) , and 3
patients had
respiratory complications ( 15 % ) . -
pubmed
Stent - related complications were identified in 4
patients ( 20 % ) , including 3
type I endoleaks , none of which were at zone 0 . -
pubmed
Spinal cord stimulation in
patients with painful
diabetic neuropathy : a multicentre randomized clinical trial . -
pubmed
To our knowledge , ours is the first multicentre randomized controlled trial investigating the effectiveness of SCS in
patients with
PDN . -
pubmed
Sixty
patients with
PDN in the lower extremities refractory to conventional medical therapy were enrolled and followed for 6 months . -
pubmed
In
patients with refractory painful
diabetic neuropathy , spinal cord stimulation therapy significantly reduced
pain and improved quality of life . -
pubmed
Autoantibody status and histological variables influence biochemical response to treatment and long - term outcomes in Japanese
patients with
primary biliary cirrhosis . -
pubmed
Associations between various factors ( including age , sex , autoantibody status and histological variables at baseline ) , biochemical response to treatment and long - term outcomes were evaluated in 164 Japanese
PBC patients . -
pubmed
CONCLUSION : Biochemical response to treatment at 2 years , which is influenced by autoantibody status and histological variables at baseline , can predict long - term outcomes in Japanese
patients with
PBC . -
pubmed
RESULTS : Data from 384
people , 213 with
diabetes , were analysed . -
pubmed
The mean ( + -sd ) age of the
people with
diabetes was 58.6 ( + -8.2 ) years and in the control subjects it was 56.1 ( + -8.6 ) years . -
pubmed
Cardiac autonomic neuropathy was present in 51 of the 138
people evaluated ( 37.0 % ; 95 % CI 28.8 - 45.1 ) . -
pubmed
We report a case of a middle aged
man who presented to us with the complaints of documented body temperature fluctuations since two months followed gradually by
hoarseness of voice ,
sexual dysfunction and
syncope . -
pubmed
Patient 's work up for secondary causes of
hypopituitarism was negative . -
pubmed
Patient was suspected as a case of
autoimmune hypophysitis and was immediately treated with
prednisolone along with hormone replacement . -
pubmed
BACKGROUND : The objective of this study was to determine the efficacy and safety of locoregional therapy ( LRT ) combined with
arsenic trioxide (
As2 O3 ) treatment in primary
hepatocellular carcinoma (
HCC )
patients . -
pubmed
METHODS : One hundred twenty - five primary
HCC patients were recruited for a randomized controlled study . -
pubmed
There were fewer
patients with extrahepatic
metastases in group A versus group B ( group A , 6 cases or 9.84 % [ 95 % CI , 2.36%-17.31 % ] ; group B , 12 cases or 18.75 % [ 95 % CI , 9.19%-28.31 % ] ) . -
pubmed
CONCLUSIONS : LRT combined with
As2 O3 treatment prevents extrahepatic
metastasis and prolongs the survival time for primary
HCC patients . -
pubmed
Sarcocystis calchasi encephalitis in a rock pigeon . -
pubmed
A
rock pigeon (
Columba livia ) caught in Akihabara , Tokyo , showed
neurological symptoms , such as head tilt and circling . -
pubmed
vaginalis ) causes
trichomoniasis , a
reproductive tract infection , in
humans . -
pubmed
In the Western hemisphere , at least five mammarenaviruses cause
human viral hemorrhagic fevers with high case fatality rates . -
pubmed
Junin virus (
JUNV ) is the only
hemorrhagic fever virus for which transfusion of survivor immune plasma that contains neutralizing antibodies ( " passive immunity " ) is an established treatment . -
pubmed
We propose that viral receptor - binding site accessibility explains the success of passive immunity against
JUNV and that this functionally conserved epitope is a potential target for therapeutics and vaccines to limit
infection by all New World hemorrhagic fever mammarenaviruses . -
pubmed
[ Efficacy of percutaneous coronary intervention in
patients with chronic
ischaemic heart disease ] . -
pubmed
BACKGROUND AND PURPOSE :
Patients with
large vessel occlusion strokes (
LVOS ) may be better served by direct transfer to endovascular capable centers avoiding hazardous delays between primary and comprehensive
stroke centers . -
pubmed
Hyperglycemia and
hypertension are considered to be two of the leading risk factors for vascular complications in diabetic
patients . -
pubmed
However , few pharmacologic agents could provide a combinational therapy for controlling
hyperglycemia and blood pressure in
diabetic patients at the same time . -
pubmed
BACKGROUND : Like
Duchenne muscular dystrophy (
DMD ) , the
Golden Retriever Muscular Dystrophy (
GRMD )
dog model of
DMD is characterized by
muscle necrosis , progressive
paralysis , and
pseudohypertrophy in specific skeletal muscles . -
pubmed
This severe
GRMD phenotype includes moderate
atrophy of the biceps femoris ( BF ) as compared to unaffected normal
dogs , while the long digital extensor ( LDE ) , which functions to flex the tibiotarsal joint and serves as a digital extensor , undergoes the most pronounced
atrophy . -
pubmed
CONCLUSIONS : The identification of elevated BF
oleic acid ( a long - chain
fatty acid ) is consistent with recent microarray studies identifying altered lipid metabolism genes , while alterations in
arginine and
proline metabolism are consistent with recent studies identifying elevated
L - arginine in
DMD patient sera as a biomarker of disease . -
pubmed
We describe two new species of the genus Xanthomonas , represented by yellow mucoid bacterial
strains isolated from diseased leaves of
watercress (
Nasturtium officinale ) produced in Florida , USA . -
pubmed
Multilocus sequence analysis and whole genome - wide comparisons of the average nucleotide identity ( ANI ) of genomes of two
strains from watercress showed that these are distinct and share less than 95 % ANI with all other known species ; the non - pathogenic
strain WHRI 8848 is close to Xanthomonascassavae ( ANI of 93.72 % ) whilst the pathogenic
strain WHRI 8853 is close to a large clade of species that includes Xanthomonasvesicatoria ( ANI & lt;=90.25 % ) . -
pubmed
Based on these results , we propose that both
strains represent new Xanthomonas species named
Xanthomonas floridensis sp . - pubmed
( type
strain WHRI 8848 = ATCC TSD-60 = ICMP 21312 = LMG 29665 =
NCPPB 4601 ) and
Xanthomonas nasturtii sp . - pubmed
( type
strain WHRI 8853 = ATCC TSD-61 = ICMP 21313 = LMG 29666 = NCPPB 4600 ) , respectively . -
pubmed
Ileocolic resection is associated with increased susceptibility to injury in a
murine model of
colitis . -
pubmed
These surgical - induced altered immune - microbial interactions in the intestine may contribute to disease
recurrence at the surgical anastomosis site following ileocolic resections in
patients with
Crohn ' s disease . -
pubmed
Human papillomavirus (
HPV ) is the most commonly
sexually transmitted infection in the world and the primary cause of
cervical cancer . -
pubmed
Studies focused on in vitro
cellular toxicity of the formulations and their single components using
A549 human lung cells showed no obvious
cytotoxicity for the formulations containing
lecithin and
PEG 32 stearate . -
pubmed
The effect of
metabolic syndrome on
recurrence in
patients who had undergone surgery for
carpal tunnel syndrome . -
pubmed
OBJECTIVES : This study aims to investigate whether or not
metabolic syndrome (
MS ) affects
recurrence in
patients who had undergone surgery for
carpal tunnel syndrome (
CTS ) . -
pubmed
Patients were examined clinically and demographically for the presence of
MS . -
pubmed
Diagnoses of
recurrence were established using electromyography in
patients with clinical
CTS and Tinel and/or Phalen test positivity . -
pubmed
CONCLUSION : Our study indicated that
MS affected
recurrence in
patients who had undergone CTS surgery . -
pubmed
WHAT IS KNOWN ALREADY : Knowledge on long - term sequelae for development and health of
children born following
PGS is lacking . -
pubmed
Proteomic profiling of integral membrane proteins associated to pathogenicity in
Vibrio parahaemolyticus strains . -
pubmed
Vibrio parahaemolyticus has been recognized as the causal agent of
early mortality syndrome and is currently considered an emerging
shrimp disease causing losses of millions in the aquaculture industry . -
pubmed
parahaemolyticus and an ATCC
strain that is pathogenic for
humans were obtained by a sequential extraction method and subjected to relative quantification and identification by isobaric Tags for Relative and Absolute Quantitation . -
pubmed
The ability to engineer primary
human B cells to differentiate into long - lived plasma cells and secrete a de novo protein may allow the creation of novel plasma cell therapies for
protein deficiency diseases and other clinical applications . -
pubmed
Mycophenolate mofetil treatment in a
patient with recurrent
lymphocytic hypophysitis . -
pubmed
We report here the case of a 58 - year - old
patient with
LHP who developed
panhypopituitarism and
bitemporal hemianopia . -
pubmed
Continuous renal replacement therapy is a standard treatment in
critically ill patients with
acute kidney injury . -
pubmed
We investigated whether a new super high - flux hemofilter provides effective and sustained middle molecule clearance during
citrate - anticoagulated continuous venovenous hemodialysis for up to 72 h. We included 14
critically ill patients with AKI - KDIGO - III in a prospective observational trial . -
pubmed
This new hemofilter may improve blood purification in
critically ill patients with
AKI . -
pubmed
Fifty - one
patients underwent an ES prior to developing primary
CBDS ( 8.9 % ) . -
pubmed
Thyroid hormone status in
patients with severe
selenium deficiency . -
pubmed
In this study , to clarify the association between
Se and
thyroid hormone status , we investigated the
thyroid hormone levels in
patients with severe
Se deficiency ( & lt ; 2 microg / dl ) . -
pubmed
However , epidemiologic studies on the relationship between endogenous levels of
melatonin and
hypertension in
humans are limited . -
pubmed
We examined the association of quartile levels of
6 - sulfatoxymelatonin ( aMT6s ) in first morning urines with prevalent and incident
hypertension in 777 postmenopausal
women who were originally part of a case - control study of
breast cancer nested in the Women 's Health Initiative Observational Study . -
pubmed
Aberrant protein glycosylation events are hallmarks of
human diseases such as
cancer and
infectious diseases . -
pubmed
METHODS : Using microarray , we performed the transcriptome - wide lncRNA and mRNAs expression profile of peripheral blood mononuclear cells ( PBMCs ) of 93
CAD patients and 48 healthy controls . -
pubmed
qRT - PCR was used to validate selected lncRNAs in 412
CAD patients and 295 healthy controls . -
pubmed
Two novel lncRNA biomarkers , ENST00000444488.1 and uc010yfd.1 , together with
CAD risk factors , had the better performance for discrimination of
CAD patients from healthy controls , and ENST00000444488.1 could diagnose
acute myocardial infarction (
AMI ) patients . -
pubmed
Frequency and
coinfection between genotypes of
human papillomavirus in a population of asymptomatic women in northern Peru . -
pubmed
The occurrence observed in this case implies that
patients with
TCM should be monitored closely for
arrhythmias , and , if such a condition is identified , planning for permanent pacemaker implantation should be started early enough to avoid recurrent life - threatening episodes . -
pubmed
Pharmacogenomics and personalized medicine will soon be part of
CF patient care . -
pubmed
Growing the phenotype of
chronic lymphocytic inflammation with pontine perivascular enhancement responsive to
steroids ( CLIPPERS ) in
children . -
pubmed
Outcome of two
patients with
bilateral nephroblastomatosis /
Wilms tumour treated with an add - on
13 - cis retinoic acid therapy - Case report . -
pubmed
We added
13 - cis retinoic acid to the standard chemotherapy with
vincristine and
actinomycin - D in two
patients with bilateral
nephrogenic rests /
nephroblastomatosis . -
pubmed
Patient 1 also had a history of
Wilms tumour . -
pubmed
46 (
patient 1 ) and 81 ( patient 2 ) months after end of treatment , both
patients show stable conditions with no signs of
relapse or progressive disease . -
pubmed
Our observation supports further investigation of
retinoic acid in
patients with
nephrogenic rests and
nephroblastomatosis . -
pubmed
We evaluated
patient and allograft outcomes in pediatric liver transplant recipients of
DCD livers . -
pubmed
CONCLUSION : Pediatric liver transplant recipients of
DCD allografts have comparable
patient and allograft survival when compared to DBD allograft recipients . -
pubmed
MATERIALS AND METHODS : Plasma was sampled from 10 healthy
subjects and 10
patients with
diabetes . -
pubmed
METHODS :
Dogs were randomly divided into the sham - operated group ( SO ; n = 6 ) ,
AMI group (
AMI ; n = 8) and the group undergoing LOMLSPV ablation ahead of
AMI ( LOMD+
AMI ; n = 8) . -
pubmed
To determine the true therapeutic effects of LOTUS , we used a more clinically relevant contusive
SCI model in female transgenic
mice . -
pubmed
Protective Effects of
Nicorandil on Cardiac Function and Left Ventricular Remodeling in a
Rat Model of
Ischemic Heart Failure . -
pubmed
Moreover , the composite fiber was able to be stitched onto a highly stretchable elastic bandage using a sewing machine to produce a wearable
strain sensor for the detection of diverse
human motions . -
pubmed
RESULTS : The majority of the
patients were pubescent ( 31.8 % ) males ( 56.8 % ) , and the main aetiology of the
burn was flammable substances ( 75 % ) . -
pubmed
To identify bacterial factors required for transmission , we conducted a high - throughput genetic screen with a transposon sequencing ( Tn - seq ) library of a
pneumococcal strain in a ferret transmission model . -
pubmed
Here , we report novel pathological defects in skeletal muscle fibres of
mouse models and patients with
NM : irregular spacing and morphology of nuclei ; disrupted nuclear envelope ; altered chromatin arrangement ; and disorganisation of the cortical cytoskeleton . -
pubmed
At day 75 ,
rats who had developed
NO2 - induced
emphysema were then divided into
sodium hydrosulfide (
NaHS ) administrated group , placebo (
NaCl ) group and spontaneous recovery group for about one month ( days 76 - 105 ) ; Pulmonary function ( PF ) and hematological and biochemical indices were measured at days 14 , 45 , 75 , and 105 . -
pubmed
CONCLUSIONS :
NO2 exposure causes
emphysema and a decline in PF in
rats . -
pubmed
Hearing Preservation With the Use of Flex20 and
Flex24 Electrodes in
Patients With Partial
Deafness . -
pubmed
OBJECTIVE : We investigated the impact of
depressed mood (
dysphoria ) and
loss of interest or pleasure (
anhedonia)on the risk of
dementia in cognitively - normal elderly
individuals . -
pubmed
METHODS : This study included 2,685 cognitively - normal elderly
individuals who completed the baseline and 4 - year follow - up assessments of the Korean Longitudinal Study on Cognitive Aging and
Dementia . -
pubmed
CONCLUSION :
Anhedonia , but not
dysphoria , is a risk factor of
dementia in cognitively - normal elderly
individuals . -
pubmed
In
children with
cancer , the issues related to the quality of life are becoming increasingly important together with the improvement of survival rates . -
pubmed
Ultrastructural markers of tissue endometrial receptivity in
patients with recurrent
implantation failure . -
pubmed
The scanning electron microscopy of the endometrial surface epithelium during the ' implantation window ' was performed in 119
patients with uterine factor of
infertility or
recurrent miscarriage due to
endometrial hypoplasia . -
pubmed
Epiploic appendagitis as unusual cause of acute
abdominal pain : Clinical and radiologic features of 7
patients . -
pubmed
Characterization of Circulating
Clostridium difficile Strains , Host Response and Intestinal Microbiome in Hospitalized Children With
Diarrhea . -
pubmed
BACKGROUND :
Clostridium difficile is capable of causing severe
enterocolitis in adults . -
pubmed
CONCLUSIONS : Children with
diarrhea regularly carried toxigenic and non - toxigenic
strains of
C. - pubmed
The feed additive Aviax 5 % , containing the active substance
semduramicin sodium , an ionophore anticoccidial , is intended to control
coccidiosis in
chickens for fattening at a dose of 20 - 25 mg / kg complete feed . -
pubmed
Aviax 5 % at a minimum dose of 20 mg / kg feed has the potential to effectively control
coccidiosis in
chickens for fattening . -
pubmed
Breaking down walls : a qualitative evaluation of perceived emergency department delays for
patients transferred with ST - elevation
myocardial infarction . -
pubmed
While
metformin has been shown to have pleotropic effects on
glucose metabolism , there is a general consensus that the major
glucose lowering effect in
patients with
type 2 diabetes is mostly mediated through inhibition of hepatic gluconeogenesis . -
pubmed
A network approach to investigating the key microbes and stability of gut microbial communities in a
mouse neuropathic pain model . -
pubmed
We collected 66 fecal samples over 2 weeks ( three
mice and 11 time points in spared
nerve injury - induced
neuropathic pain and Sham groups ) . -
pubmed
RESULTS : Here we show that spared
nerve injury - induced
neuropathic pain alters gut microbial diversity in
mice . -
pubmed
Oscillospira , which was classified as a low - abundance and core microbe , was identified as the key microbe in the Sham group , whereas
Staphylococcus , classified as a rare and non - core microbe , was identified as the key microbe in the spared
nerve injury - induced
neuropathic pain group . -
pubmed
Further improvement in glycemic control after switching from
exenatide two times per day to exenatide once - weekly autoinjected suspension in
patients with
type 2 diabetes : 52 - week results from the DURATION - NEO-1 study . -
pubmed
RESEARCH DESIGN AND METHODS : In this phase III open - label study ,
adults with
type 2 diabetes were randomized to receive exenatide QWS - AI ( 2 mg ) or exenatide two times per day ( 5 mcg for 4 weeks , followed by 10 mcg ) for 28 weeks . -
pubmed
CASE REPORT A 54 - year - old
man with recent COVID-19 exposure presented with
fever ,
cough ,
dyspnea , and
syncope and was found to be in
hypoxic respiratory failure requiring supplemental
oxygen . -
pubmed
A bedside echocardiogram can provide valuable information in
patients with suspected high - risk
pulmonary embolism and hemodynamic instability . -
pubmed
METHODS : This paper presents a novel technique called Smart
Sepsis Predictor ( SSP ) to predict
sepsis onset in
patients admitted to an intensive care unit ( ICU ) . -
pubmed
METHODS : Single - institution prospective cohort study of
patients requiring craniotomy for
brain tumor resection operated using an electromagnetic navigation system ( AxiEM , Medtronic ) . -
pubmed
CONCLUSION : The information provided by the IONM in intracranial neurosurgery
patients whilst also using electromagnetic navigation systems is reliable for monitoring , mapping , and detecting
intraoperative complications , provided that the appropriate software filters and tools are applied . -
pubmed
We aimed to assess outcomes in
stroke patients treated with different endovascular procedures versus direct MT alone for isolated M2 - MCA occlusion . -
pubmed
We conducted a cohort study on data from 506
stroke patients with isolated M2 - MCA occlusion who were enrolled in the Italian Registry of Endovascular Treatment in Acute
Stroke cohort . -
pubmed
In
stroke patients with isolated M2 - MCA occlusion ,
MT plus IAT was associated with better outcomes as compared with direct MT alone . -
pubmed
[ Thrombocyte kinetics in
children with
idiopathic thrombocytopenic purpura after splenectomy ] . -
pubmed
Therefore a study was carried out in our laboratory on the cellular characteristics of the epididymal depot of the Fisher 344
strain of
rats through virtually the entire life - span . -
pubmed
During the
chronic infection , toxins of
P. - pubmed
Fifty - six femoral non infected anastomotic false
aneurysms (
FAAs ) were observed in 49
patients admitted to the Institute of Vascular Surgery , University of Milan , from 1975 to 1988 ; in 6
patients they were bilateral . -
pubmed
A history of
hypertension was present in 30 % of the
patients . -
pubmed
In 5
patients aneurysm resection was carried out on both sides . -
pubmed
Lung torsion : survival of a
patient whose
hemorrhagic infarcted lung remained in situ after detorsion . -
pubmed
To test the hypothesis that
chloral hydrate can cause direct
hyperbilirubinemia (
DHB ) in the newborn , two retrospective analyses of the medical records of
patients admitted to a neonatal intensive care unit during an 18 - month period were conducted . -
pubmed
The anticancer properties of these
esters have been compared with those of
DFMO and
MAP as a function of the dose , the route of administration , and the stage of the lewis
lung carcinoma development in
mice . -
pubmed
shortly after cell inoculation at one - fifth the dose of
DFMO , prolonged the survival of
mice - bearing
leukemia to the same extent as
DFMO and
MAP . -
pubmed
When administered orally to
leukemia - bearing
mice the two
esters were equipotent at prolonging survival . -
pubmed
, maximum prolongation of the
mice survival ( 79 % ) occurring at 0.5 g / kg
methyl ester every 12 h. The two
esters achieve at one - sixth to one - twelfth the dose , antitumor effects similar to
DFMO in the
Lewis lung carcinoma model , the
ethyl ester being slightly , but not significantly , more effective than the
methyl ester when administered orally . -
pubmed
A
patient with
acute myeloid leukemia (
AML ) who developed probable
aspergillosis of the lung underwent partial lobectomy prior to allogeneic bone marrow transplantation ( BMT ) . -
pubmed
Histopathologic alterations in the decidua in
human spontaneous abortion : loss of cells with large cytoplasmic granules . -
pubmed
Since the presence of suppressor cell activity in
murine decidua correlates with the success of pregnancy and since this suppression is associated with small lymphocytes with cytoplasmic granules , the observations made using
human placental bed biopsy material suggest that a possible suppressor cell deficiency might occur in the early stages of
spontaneous abortion in
human females . -
pubmed
This rapidly released antigenic / allergenic component may play an important role in the initiation of immunologic responses in
patients with
allergic bronchopulmonary aspergillosis . -
pubmed
[ Phytolysin in the complex treatment of
patients with
chronic suppurative otitis media ] . -
pubmed
A prospective blinded randomized study was carried out to determine the effect of antepartum administration of
dexamethasone on the incidence of
respiratory distress syndrome in 250
patients with gestations between 28 and 33 weeks complicated by
premature rupture of membranes . -
pubmed
The incidence of
respiratory distress syndrome was not lowered by the length of
rupture of membranes in the 124 untreated
patients . -
pubmed
Repair of
osteochondral defects in articular weightbearing areas in the
rabbit 's knee . -
pubmed
( 2 ) The percentage of ABG - bound plasma
aldosterone was found to vary with the seasonal change in temperature and the hepatic function of
CF patients . -
pubmed
The authors report another case of successful endocavitary electrocautery in a young
woman with
Wolff - Parkinson - White syndrome . -
pubmed
[ Identification of animal
strains of
Clostridium welchii by the agglutination test . -
pubmed
Congenitally abnormal vision in Siamese
cats . -
pubmed
The effect of topical
vitamin A on
papillomas and
intraepithelial carcinomas induced in
hamster cheek pouches with
9,10 - dimethyl-1,2 - benzanthracene . -
pubmed
[ Changes in the
oxygen deficiency tolerance in
man induced by psychopharmaca ] . -
pubmed
Sixty - six
patients with advanced
head and neck cancer 57 of whom had failed to respond to prior irradiation , were treated according to two protocols . -
pubmed
Group I consisted of 41
patients in
relapse who received a monthly combination of
bleomycin ,
vincristin ,
methotrexate and
hydroxyuera . -
pubmed
Before any chemotherapy , 62 p. 100 of the relapsing
patients gave negative responses to delayed
hypersensitivity skin tests to recall antigens . -
pubmed
Survival of
patients with metastatic
recurrence was significantly higher than survival in
patients with local recurrence . -
pubmed
Uterine infections in three mares following repeated uterine manipulations and antibiotic therapy were caused by
Aspergillus fumigatus in two cases and
Candida albicans in the third . -
pubmed
The aim of this prospective work was to analyze the results of 3 methods of esophageal pH recording ( i. e. short - term pH test , 3 - hr postprandial recordings , and 12 - hr nocturnal pH recording ) in 47
patients with suspected
gastroesophageal reflux . -
pubmed
According to the results of nocturnal pH recordings , 32
patients were considered to suffer from acid
gastroesophageal reflux and 15
patients as being free of
reflux . -
pubmed
Because of the absence of lamina propria in the biopsy specimens obtained at endoscopy , histological diagnosis of
esophagitis was possible in only 35
patients ( 74 p. 100 ) . -
pubmed
Acute
toxicity of
hydrazine hydrate to the
fathead minnow (
Pimephales promelas ) and
daphnid (
Daphnia pulex ) . -
pubmed
In the experience of one of the authors with outpatient
cataract and intraocular lens surgery , 66.7 percent of
outpatients achieved visual acuity of 20/40 or better and 33.3 percent of inpatients achieved visual acuity of 20/40 or better . -
pubmed
Rats treated with
TET bromide ( 30 mg / liter ) in their drinking water for 3 weeks showed a profound decrease in acoustic startle reflex amplitudes which was apparent prior to overt
neuromuscular weakness and subsequent hindlimb
paralysis . -
pubmed
Serological markers for
hepatitis B virus in male homosexuals demonstrated a high prevalence of past and present
infection . -
pubmed
Preliminary report on
mellituria in
phenylketonuric children : modification in the excretion of
glucose and
pentoses . -
pubmed
Colonic
adenocarcinoma with
cutaneous metastasis in a
dog . -
pubmed
METHODS : Ninety consecutive
patients ( 50
males , 40
females ) , 80 percent of whom had second or third degree
hemorrhoids , had ambulatory hemorrhoidectomy performed with a
CO2 laser in the left lateral Sims position under local anesthesia and intravenous sedation . -
pubmed
RESULTS : One
patient with
polycythemia vera was admitted subsequently for secondary
hemorrhage . -
pubmed
For comparison we also studied 66
patients with
benign lung diseases and nine with
pleural mesothelioma . -
pubmed
In
patients with
SCLC , high levels of all markers except
SCC were found when the disease was extensive . -
pubmed
Increased brain
QUIN levels have also been shown in acute
hyperammonemic rats . -
pubmed
The
NH4Ac administration induced
coma in all of the PCS
rats 20 - 25 min after the challenge , and this
coma was resolved within 60 - 75 min . -
pubmed
The capacity of inhibiting the carrageenan - induced
edema in the
rat paw and the writhes induced by
acetic acid in
mice were evaluated , as well as the ulcerogenic action in
rats . -
pubmed
The last
patient also had
type II PGA syndrome . -
pubmed
In vivo secretory responses of submandibular glands in
streptozotocin -
diabetic rats to sympathetic and parasympathetic nerve stimulation . -
pubmed
Submandibular gland responses to sympathetic and parasympathetic nerve stimulation were studied in
streptozotocin -
diabetic rats . -
pubmed
In 6 - month
diabetic rats flow rate remained increased , but protein concentration and
total protein output were reduced . -
pubmed
[
Renal tubular acidosis in
children ] . -
pubmed
METHODS : To assess the feasibility of therapeutic fetal
heart block , we developed a technique of intrauterine cryosurgical ablation of fetal atrioventricular node without the need for cardiac bypass in 8 fetal
lambs . -
pubmed
Patients were excluded if they had prior peritoneal lavage , bladder or
bowel injury , or low hematocrit values . -
pubmed
Only 6 ( 14 % ) of 42
patients had mean attenuation values greater than 40 H , whereas 4 ( 10 % ) of 42 patients had mean attenuation values less than 20 H. The remaining 32 patients ( 76 % ) had mean attenuation values between 21 and 40 H. Patients with
hepatic lacerations showed no significant difference ( p = .3509 ) in attenuation between perihepatic fluid and the remainder of intraperitoneal fluid . -
pubmed
Heterogeneous T cell receptor V beta gene repertoire in
murine interstitial nephritis . -
pubmed
In vivo studies in which
UCN-01 was administered by continuous intraperitoneal infusion in subcutaneous and intracranial intraparenchymal
nude rat models demonstrated significant activity against
U-87 glioma xenografts at dose levels that were well tolerated . -
pubmed
Urine autoantibodies that bound to normal
human bladder epithelial cells were present in 8 of 14 IC specimens ( from 6 of 9
IC patients ) as compared to 3 of 23 control specimens ( from 2 of 17 control
patients ) . -
pubmed
Three
IBDV strains were examined after propagation in different hosts . -
pubmed
The RE profiles of the STC and MD
IBDV strains did not change after propagation in either
BGM-70 cell culture or
chicken bursas , whereas the Del - A RE profile changed at the Sau3AI site after adaptation to
BGM-70 cell culture . -
pubmed
We describe an approach which combines proteome analysis ( mapping of expressed proteins isolated by two - dimensional
polyacrylamide gel electrophoresis to the genome ) with genetic manipulations to study the complex pattern of protein regulation occurring in
Escherichia coli in response to
sulfate starvation . -
pubmed
We have previously described the upregulation of eight
spots on two - dimensional ( 2 - D ) gels in response to
sulfate starvation and the assignment of six of these to entries in the
E. - pubmed
METHODS : Thirty - seven eyes of 37 normal - tension
glaucoma (
NTG )
patients were examined . -
pubmed
CONCLUSIONS : These data indicate that the absence of residual pancreatic beta - cell function in
patients with
insulin - dependent diabetes mellitus is associated with
neuroendocrine dysfunction in the regulation of circadian TSH secretion , which is not reversible after restoration of good glycaemic control . -
pubmed
The position and length of the
steroid - dependent hypersensitive region in the
mouse mammary
tumor virus long terminal repeat are invariant despite multiple nucleosome B frames . -
pubmed
Patients with early
Alzheimer ' s disease (
AD ) were compared to normal controls and
patients with early
vascular dementia (
VaD ) on their naming errors using the Boston Naming Test ( H. Goodglass & E. Kaplan , 1983 ) . -
pubmed
Interestingly , our monoclonal antibodies also reacted with two other Plasmodium species (
Plasmodium berghei NKK173
strain and
P. - pubmed
Lentigo maligna (
LM ) is well known as an irregularly pigmented
macular lesion usually presenting on the sun - damaged head and neck of older
patients . -
pubmed
The purified virus contains all of the genetic information required for its
infection cycle as it readily replicated in
cowpea protoplasts and systemically infected
Vicia faba seedlings that were biolistically inoculated using gold particles coated with intact virions or viral DNA . -
pubmed
The bombarded plants not only developed the typical disease
syndrome , thus indicating that
FBNYV is the sole causal agent of the disease , but also served as a source from which the virus was readily acquired and transmitted by
A. - pubmed
Early alterations in gene expression and cell morphology in a
mouse model of
Huntington ' s disease . -
pubmed
Several
mouse models for
Huntington ' s disease (
HD ) have been produced to date . -
pubmed
We decided to analyze the morphology of striatum and hippocampus from a
mouse transgenic line obtained by microinjection of exon 1 from the
HD gene after introduction of a very high number of CAG repeat units . -
pubmed
DESIGN / METHODS : We report a series of 2 normal newborn
patients who had a large prenatal unilateral
intracranial cyst diagnosed by PSG in the 10 years between July of 1989 and 1999 at a rural community hospital . -
pubmed
We studied 18 eligible
patients with low - grade and 21
patients with intermediate- or high - grade
NHL . -
pubmed
One
patient in the intermediate / high - grade
NHL group developed a partial response lasting longer than 15 months ( 5 % ; 95 % CI 0 - 24 % ) . -
pubmed
Cardiac toxicity ,
gastrointestinal ulceration and
nasal congestion due to rhuIL-4 were not prominent
toxicities in our
patients . -
pubmed
Our previously treated
NHL patients tolerated s.c . -
pubmed
Genetically obese ,
leptin - deficient ob / ob
mice are models for
nonalcoholic fatty liver disease (
NAFLD ) , a type of
liver disease that is strongly associated with
obesity and
type 2 diabetes . -
pubmed
Similar to
obese ,
diabetic patients , ob / ob
mice have an increased incidence of
HCC . -
pubmed
However , unlike
humans with
NAFLD , they rarely , if ever , develop
cirrhosis spontaneously . -
pubmed
To determine whether the noncirrhotic livers of ob / ob
mice with
NAFLD exhibit
hepatocyte hyperplasia , parameters of proliferation and apoptosis were compared in adult ob / ob
mice and their healthy litter mates . -
pubmed
Thus ,
liver hyperplasia is evident at the earliest stage of
NAFLD in ob / ob
mice , which supports the concept that
obesity - related
metabolic abnormalities , rather than
cirrhosis , initiate the hepatic
neoplastic process during
obesity . -
pubmed
Concerning
HSV- and
VZV - prophylaxis there are almost no differences between recommendations of the german society and the american institutions , however recommendations for preventing
CMV - disease and
CMV - recurrence do differ considerably . -
pubmed
VZV vaccination or
CMV prevention , should be studied in oncology and
infectious diseases working groups to define consensus in the near future . -
pubmed
RESULTS :
Animal models of
abnormal gastrointestinal motility were established in
mice and
rats . -
pubmed
This report describes the early magnetic resonance imaging ( MRI ) findings and long - term follow - up results of
albendazole treatment in a 16 - year - old
girl with primary
hydatid disease of the femur diagnosed incidentally during the course of a
post - traumatic knee infection . -
pubmed
[
Tuberculosis in elderly
patients ] . -
pubmed
Medicinal treatment of intractable
dyspnea in terminally ill
patients . -
pubmed
We report a very rare case of a simultaneous
rupture of the right patellar and left quadriceps tendon in an otherwise healthy 37 - year - old
patient , who jumped off a kickboard . -
pubmed
A series of 42
patients with 45 rectal
tumors ( 9
adenomas , 36
adenocarcinomas ) who underwent gasless VTEM between 1993 and 2000 were studied prospectively . -
pubmed
During the median follow - up length of 73.3 months , no
patient developed
tumor recurrence in the gasless VTEM group , whereas one
patient did in the control group . -
pubmed
The influence of
steatosis on the outcome of orthotopic liver transplantation ( OLT ) was evaluated in 860 liver transplantations carried out in 784
patients from October 1990 to August 2001 . -
pubmed
Macrovesicular steatosis affecting 15 % or more of the hepatocytes was the only variable independently associated with shorter
patient and graft survival ( P=0.0012 and 0.0028 ) . -
pubmed
A significantly worse prognosis was to be expected if & gt;15 %
macrovesicular steatosis was associated with a total
ischemia time & gt;10 h ( P=0.048 ) , or donor age & gt;65 years ( P=0.016 ) or with
HCV - positive recipients ( P=0.0014 ) . -
pubmed
The risk of graft non - function or
patient loss after OLT rises if
macrovesicular steatosis & gt;15 % is associated with long
ischemia time , high donor age , or
HCV positivity in recipients . -
pubmed
Competition among Bradyrhizobium strains for nodulation of
green gram (
Vigna radiata ): use of dark - nodule
strain . -
pubmed
The competitiveness of dual -
strain inoculum of
Bradyrhizobium strains S24 and GR4 was demonstrated for nodulation of green gram (
Vigna radiata ) . -
pubmed
The dark - brown nodule - phenotype could be useful in evaluating nodulation competitiveness of "
cowpea miscellany " bradyrhizobia in soil where dark - brown nodule - forming
strains are not indigenous . -
pubmed
Also at this time , a phase II trial in
children suffering from
GHIS was initiated . -
pubmed
The title compounds 2a - j and 3a - j were screened in vivo using carrageenan - induced
rat paw
edema model . -
pubmed
Histoplasma capsulatum variety duboisii isolated in Japan from an
HIV - infected Ugandan patient . -
pubmed
A
strain of
Histoplasma capsulatum var . - pubmed
We report on a case of
periosteal osteoblastoma arising from the posterior surface of the right distal femur in a 17 - year - old
man . -
pubmed
Conversion to laparotomy occurred in three
patients based on intraoperative findings of suspected primary
ovarian cancer and for technical reasons in one
patient . -
pubmed
Overall , metastatic
breast cancer was diagnosed in 21 ( 68 % ) of 31
patients , including two
patients with occult
metastases undergoing
BSO for hormonal ablation . -
pubmed
Primary
ovarian cancer was found in 3 ( 10 % ) of 31
patients , and 7 ( 22 % ) of 31
patients had benign findings . -
pubmed
RESULTS : Our survey suggested analgesic
nephropathy in 47 of 1400
patients ( 3.3 % ) , 3 - fold higher than the
EDTA database estimate for Hungary . -
pubmed
The results demonstrate on the one hand , very high indices of cardiovascular risk ( smoking ,
hypertension ,
dyslipidaemia and
albuminuria ) and on the other , good quality primary health care providing good detection and follow up management of
type 2 diabetic patients . -
pubmed
Effect of
ethanol extract of
Piper betle Linn leaf on healing of NSAID - induced experimental
ulcer -- a novel role of free radical scavenging action . -
pubmed
betle at a dose of 150 mg / kg
body weight daily for 10 days , after induction of
peptic ulcer by NSAID in
albino rats , produced significant healing effect . -
pubmed
Salmonella enterica serotype Enteritidis (
SE ) is a common cause of
foodborne illness in the United States . -
pubmed
Update on lymphatic mapping and sentinel node biopsy in the management of
patients with
melanocytic tumours . -
pubmed
AIMS : To communicate best practices for sentinel lymph node evaluation and assessment of prognosis for
patients with
melanoma . -
pubmed
METHODS : Description and justification of approaches derive from experience with management of more than 2000
melanoma patients evaluated by lymphatic mapping and sentinel node biopsy ( LMSNB ) . -
pubmed
Continuous renal replacement therapy ( CRRT ) is used to treat
renal failure in
children . -
pubmed
Children with high
fluid overload ( & gt;10 % ) at CRRT initiation were at 3.02 times greater risk of mortality than those with low or no fluid overload [ 95 % confidence interval ( CI ) 1.50 - 6.10 , P=0.002 ] . -
pubmed
OBJECTIVE : To determine the incidence and risk factors for post - ICU mortality in
patients with
infection . -
pubmed
PATIENTS : All 1,872
patients discharged alive from the ICU over a 1 - year period were screened for
infection at ICU admission and daily throughout the ICU stay . -
pubmed
Campylobacter jejuni is a leading cause of
bacterial gastroenteritis in the developed world . -
pubmed
It is concluded that soil water was not equally available to
Fraxinus mandshurica seedlings in the test ranges of soil water potential , and significant
water stress could occur when the soil water potential was lower than -40 kPa . -
pubmed
The aim of this study was to investigate over a 3 - year period the connection between
homocysteine (
Hcy ) levels and development of
Alzheimer ' s disease (
AD ) in
patients with
mild cognitive impairment (
MCI ) . -
pubmed
Thirty - three percent of
men with
Hcy levels > 20 micromol / l converted to
AD . -
pubmed
The corresponding figure for men with
Hcy levels 20 - 17 micromol / l was 50 % , whereas none of the 18
men with
Hcy levels < 17 micromol / l converted to
AD . -
pubmed
There was also a statistically significant difference between the percentage of
women with
Hcy levels > 16 micromol / l who converted to
AD ( 45 % ) as compared to those with
Hcy levels < 16 micromol / l who converted ( 21 % ) . -
pubmed
However , our findings tentatively suggest a possible protective effect of low / normal
Hcy levels on
dementia conversion in
MCI patients . -
pubmed
During the more difficult three - operand task ,
individuals with
TS demonstrated significantly less activation in frontal , parietal and subcortical regions than controls . -
pubmed
Individuals with
TS demonstrate activation differences in fronto - parietal areas during arithmetic tasks compared with controls . -
pubmed
Past accidental
poisonings in
humans show that exposure to high levels of either contaminant is associated with motor impairments , including alterations in cerebellar functions such as balance and coordination . -
pubmed
Epidemiological studies of lower level exposures suggest some
neuromotor impairment in exposed
children , but the majority of these studies have focused on cognitive endpoints rather than examining a full - range of motor function . -
pubmed
Clinical and experimental findings in
humans and animals with chemotherapy - induced
peripheral neuropathy . -
pubmed
The pilot trial included 11
patients with acute - on -
chronic liver failure and concomitant
renal failure . -
pubmed
Thus , Prometheus might be a new therapeutic option in
patients with severe
hepatorenal syndrome . -
pubmed
Antiproliferation and apoptosis induced by
C - glycosides in
human leukemia cancer cells . -
pubmed
The treatment of
mice with
clenbuterol ( 2 mg / kg body wt for 30 days ) resulted in skeletal
muscle hypertrophy , more common amongst fast - twitch glycolytic fibres / muscle , with increase in body mass and a parallel rise in muscle mass to body mass ratio . -
pubmed
Measurement of fibre diameters in soleus ( rich in slow - twitch oxidative fibres ) ,
ALD or anterior latissimus dorsi ( with a predominance of fast - twitch glycolytic fibres ) and gastrocnemius ( a mixed - type of muscle ) from
clenbuterol - treated
mice for 30 days revealed noticeable increase in the per cent population of narrow slow - twitch fibre and a corresponding decline in white - type or fast - twitch glycolytic fibres in gastrocnemius and
ALD . -
pubmed
Th2 - dominant immune response , possibly caused by concurrent
bacterial or parasitic infections , could explain , in part , the lower risk of
H. - pubmed
BACKGROUND : Nonrandomized studies suggest that atrioventricular ( AV ) junction ablation and pacemaker implantation may improve quality of life , ejection fraction , and exercise tolerance in
patients with symptomatic drug - refractory
atrial fibrillation . -
pubmed
[ Protective effect of
melatonin and
sodium thiosulphate on histopathology and ultrastructure of the kidney in
rats with acute
paraquat poisoning ] . -
pubmed
Actions of
N - arachidonyl - glycine in a
rat neuropathic pain model . -
pubmed
In the present study we examined the effect of
NAGly in a
rat model of
neuropathic pain . -
pubmed
METHODS : A panel of 64 serum biomarkers was analyzed in sera of
patients with
stages I - III endometrial cancer and age - matched healthy women , utilizing a multiplex xMAP bead - based immunoassay . -
pubmed
Anatomic distribution and electrophysiologic properties of
accessory atrioventricular pathways in
dogs . -
pubmed
ANIMALS : 10
dogs with
tachyarrhythmias associated with an AP . -
pubmed
PROCEDURES : Each
dog underwent electrophysiologic testing to determine the inducibility of documented and undocumented
arrhythmias and to identify location , conduction properties , and antegrade and retrograde effective refractory periods of the APs . -
pubmed
RESULTS : 15 APs were identified ; 7
dogs each had a single
AP , and 3 had multiple
APs . -
pubmed
All documented
tachyarrhythmias could be induced during electrophysiologic testing ;
atrial fibrillation was also inducible in 2
dogs . -
pubmed
CONCLUSIONS AND CLINICAL RELEVANCE : Results suggested that in
dogs , most APs are right - sided , had unidirectional retrograde conduction , and are associated with various
arrhythmias , including orthodromic
atrioventricular reciprocating tachycardia and
atrial fibrillation without evidence of pre - excitation . -
pubmed
PATIENTS : Twelve
men with
IHH ( age 40.8 + /- 2.8 yr ) were studied : 1 ) on hormone replacement with normal T levels and 2 ) 2 wk after discontinuing therapy . -
pubmed
Seven
strains of
Listeria monocytogenes and 8 of their derivative
strains were screened for their capacity to form biofilms . -
pubmed
Aspergillosis was identified in 10 cases ( 3.6 % ) and diagnosis was confirmed when clinical symptoms were associated with identification of Aspergillus
sp . -
pubmed
Incidence of
Aspergillosis considerably decreased from 6.9 % to 0.6 % when liposomal
amphotericin B was introduced as prophylaxis in high - risk
patients . -
pubmed
Two
patients ( 20 % ) died because of
Aspergillosis Liposomal
Amphotericin B prophylaxis in high - risk children decreases the incidence of
Aspergillus infection . -
pubmed
OBJECTIVE : To know relative dose intensity ( RDI ) in
patients with
breast cancer treated with chemotherapy . -
pubmed
Esophageal hypersensitivity is one of the most common causes of noncardiac
chest pain in
patients . -
pubmed
We conclude that enhanced responses of thoracic spinal neurons to ED by the chemically challenged esophagus may provide a possible pathophysiological basis for
visceral hypersensitivity in
patients with
gastroesophageal reflux and/or
esophagitis . -
pubmed
Aldohexose malabsorption in preterm
pigs is directly related to the severity of
necrotizing enterocolitis . -
pubmed
Therefore , a preterm
pig model that spontaneously develops
NEC was used to investigate the relationship between severity of
NEC lesions and
galactose absorption in vivo and carrier - mediated
glucose absorption by intact mid small intestine . -
pubmed
Pigs were killed when symptoms of
NEC were observed or after 36 - 40 h of enteral nutrition . -
pubmed
Though the serological test showed no positive antibody titer against
Rickettsia japonica ,
Rickettsia japonica was isoleted from blood culture , to confirm
Japanese spotted fever ,
Japanese spotted fever is generaly a curative disease with early diagnosis and
minocycline . -
pubmed
Evolutionary relationships between sporadic and epidemic
strains of healthcare - associated
methicillin - resistant
Staphylococcus aureus . -
pubmed
No significant drug influence was observed on the
anxiety - related
mice behavior in the light / dark test . -
pubmed
IBS was subsequently compared with histologic findings of the respective tissue in 10
patients who underwent endarterectomy . -
pubmed
These data suggest that these high - drinking lines may represent an unexpectedly appropriate complex model of how multiple factors may contribute to the genesis of
human alcoholism . -
pubmed
OBJECTIVE : To evaluate the relationship between renal activity and quality of life ( QOL ) in
patients with
systemic lupus erythematosus (
SLE ) . -
pubmed
METHODS : Three hundred eighty - six
patients completed annual Medical Outcomes Study Short Form-36 questionnaires and physicians completed the
SLE Disease Activity Index and Systemic Lupus International Collaborating Clinics / American College of Rheumatology Damage Index . -
pubmed
Single
nucleotide polymorphisms of cytokine genes are associated with
fibrosis of the intrahepatic bile duct wall in
human clonorchiasis . -
pubmed
BACKGROUND :
Seizures are poorly controlled in many
people with
epilepsy , despite current antiepileptic treatments . -
pubmed
OBJECTIVES : To determine the effectiveness and safety of traditional Chinese medicine in
people with
epilepsy . -
pubmed
METHODS : One hundred and seven consecutive
patients with 110 wide - necked or fusiform
intracranial aneurysms were treated with the Neuroform stent - assisted coiling . -
pubmed
Angiography follow - up was obtained in 45.8 % ( 49/107
patients ; 51/110
aneurysms ; average follow - up time : 37.2 months ) . -
pubmed
One
patient with in - stent
stenosis and one with
penetrating artery occlusion occurred as delayed complications . -
pubmed
Recently , the
Arabidopsis -
Colletotrichum higginsianum ( causal agent of anthracnose ) system has emerged as a seminal paradigm for deciphering the
infection biology underlying fungus - plant interactions . -
pubmed
Trypan blue and
aniline blue staining were employed to scan the
infection structures of the hemibiotrophic fungus
C. - pubmed
BACKGROUND :
Individuals with
medial knee osteoarthritis often present with varus knee alignment and ambulate with increased knee adduction moments . -
pubmed
Second , as only few population - based studies are available , the prevalence of oxidative stress among
CKD patients remains undetermined . -
pubmed
Finally , while two recent pilot studies have demonstrated that treatment of
CKD patients with antioxidants is able to reduce cardiovascular events , information related to the pharmacokinetic characteristics of antioxidants , as well as their efficacy to prevent oxidative stress , is still limited in this
patient group . -
pubmed
METHODS : Thirty
subjects with clinical diagnosis of
primary open angle glaucoma and 30 healthy
subjects were recruited . -
pubmed
Semaphorins of the SemaIV family are expressed in neurons and decreased in brains from
patients with
Alzheimer ' s disease (
AD ) . -
pubmed
The significant antimalarial potential was revealed by a 100 % cure rate of
malaria in
mice with one administration of 100 mg / kg of 1 . -
pubmed
Ventricular function and all - cause mortality in
chronic kidney disease patients with angiographic
coronary artery disease . -
pubmed
Traditional and nontraditional risk factors ,
hypertension , fluid overloading and
anemia can lead to
myocardial ischemia , chamber
hypertrophy and dilatation , and low left ventricular ejection fraction ( LVEF ) in
CKD patients . -
pubmed
The angiographic feature , ventriculographic LVEF and its relationship to all - cause mortality are unclear in
patients with different stages of
CKD who are not yet on dialysis . -
pubmed
METHODS : This retrospective study involved 980
CKD patients with suspected
myocardial ischemia who underwent coronary angiography from 1995 to 2004 . -
pubmed
RESULTS : Of the
CKD patients , 445 ( 45.4 % ) had angiographic
CAD . -
pubmed
Low LVEF was the only independent significant prognostic factor in
CKD patients with angiographic
CAD ( HR=0.957 ; 95 % CI , 0.918 - 0.996 ) . -
pubmed
Community - acquired
pneumonia (
CAP ) is a common and potentially serious illness with significant
human and economic costs to society . -
pubmed
Pregabalin and
edema in young
women suffering from
premenstrual syndrome . -
pubmed
METHODS : From December 2005 to December 2008 , 54
patients with
cervical syndrome ( 34 males and 20 females , the age was from 39 to 69 years with an average of 50.5 ) were treated with single level Bryan prosthetic cervical disc replacement . -
pubmed
RESULTS : The
pain symptom and neurological function of all 54
patients were improved obviously . -
pubmed
PHPT is asymptomatic for 80 % of
patients and responsible for a decrease in bone mineral density particularly in women . -
pubmed
METHODS : We performed a prospective analysis of
patients with
PHPT in order to evaluate the prevalence of
vitamin D deficiency . -
pubmed
RESULTS : 75
patients with
PHPT were identified : 38
patients with
vitamin D deficiency but only 22
patients could be followed ( G1 ) . -
pubmed
Basophils are important effector cells , which contribute to protection against
helminths and execute proinflammatory effector function during
allergic inflammation . -
pubmed
Silent
ischemia normalized for coronary collateral function in
patients with and without
diabetes mellitus . -
pubmed
It appears to be spreading to new areas with several countries reporting their first
human cases of
CCHF disease within the past 10 years . -
pubmed
It is capable of detecting
strains from all 7 groups of
CCHF , including the AP92
strain that until recently represented a lineage of
strains that were not associated with
human disease . -
pubmed
BACKGROUND :
Tranexamic acid (
TXA ) has been shown to reduce
blood loss in surgical
patients and the risk of
death in
patients with
traumatic bleeding , with no apparent increase in vascular occlusive events . -
pubmed
OBJECTIVE : The Clinical Randomisation of an Antifibrinolytic in Significant
Haemorrhage Intracranial Bleeding Study ( CRASH-2 IBS ) was conducted to quantify the effect of an early short course of
TXA on
intracranial haemorrhage and new focal
cerebral ischaemic lesions in
patients with
TBI . -
pubmed
Patients eligible for inclusion in the CRASH-2
IBS fulfilled the inclusion criteria for the CRASH-2 trial , and also had
TBI [ Glasgow Coma Scale score of & lt;= 14 and a brain computerised tomography ( CT ) scan compatible with
TBI ] . -
pubmed
CONCLUSIONS : This was the first randomised controlled study to evaluate the effect of
TXA in
TBI patients and it found that neither moderate benefits nor moderate harmful effects can be excluded . -
pubmed
However , although uncertainty remains , our analyses suggest that
TXA administration might improve outcome in
TBI patients and provide grounds for evaluating this hypothesis in future research . -
pubmed
This article will give a short overview on the most common
animal models and a comprehensive overview on markers for
sepsis in animal models and clinical studies . -
pubmed
Patient charts were reviewed regarding
cardiac arrest variables and treatment data of all
patients from 1993 to 2010 . -
pubmed
The first recorded ECG rhythm showed pulseless electric activity in 23 ( 42 % ) ,
ventricular fibrillation in 21 ( 38 % ) and
asystole in 11 ( 20 % )
patients . -
pubmed
Cardiac arrest occurred out - of - hospital in 33 ( 60 % )
patients . -
pubmed
In this seemingly desperate
patient population after prolonged
cardiac arrest , we observed a high survival rate of 15 % . -
pubmed
Linear growth and neurodevelopmental outcome of
children with
congenital hypothyroidism detected by neonatal screening : A controlled study . -
pubmed
INTRODUCTION : Different growth and neuro - developmental outcomes have been associated with different doses of
thyroxine given to
infants with
congenital hypothyroidism (
CH ) . -
pubmed
RESULTS :
Birth weight , length , and head circumference of
patients ( 3.21 + - 0.43 kg , 50.5 + - 3.21 cm and 34.1 + - 1.5 cm , respectively ) did not differ than those for 10,560 normal newborns with normal thyroid function ( 3.19 + - 0.59 kg , 50.5 + - 2.2 cm and 34.2 + - 1.7 cm ) . -
pubmed
In this cross - sectional study , genomic DNA of 41
patients with permanent
CH due to
thyroid dyshormonogenesis was extracted using the salting out method . -
pubmed
To explore the mechanisms of Salmonella desiccation resistance , we studied the transcriptomic responses in
Salmonella Tennessee ( Tennessee ) , using
Salmonella Typhimurium LT2 ( LT2 ) , a
strain weakly resistant to desiccation , as a reference
strain . -
pubmed
In this study , we evaluated the clinical outcomes of this treatment approach in 75
patients with
LT . -
pubmed
Thus , induction chemotherapy followed by HCT has the potential for long - term disease control in select
patients with
LT preceded by a
MPN . -
pubmed
Consecutive eligible
patients ( n = 181 ) were divided into 3 groups :
patients with
CAE , those with newly diagnosed
coronary artery disease (
CAD ) , and those with a normal coronary angiogram . -
pubmed
The N / L ratio and MPV were significantly higher in
patients in both
CAE and
CAD groups compared to those in the control group ( P & lt ; .01 ) . -
pubmed
PURPOSE : The purpose of this study was to examine the influencing factors of
postoperative pain among
children undergoing elective surgery . -
pubmed
RESULTS :
Children experienced moderate preoperative
anxiety and
postoperative pain . -
pubmed
Boys reported less
postoperative pain than
girls . -
pubmed
PRACTICE IMPLICATIONS : Effective strategies for assessing and managing
children 's preoperative
anxiety are needed to achieve an optimal postoperative
pain management outcome . -
pubmed
The universe is made up of 60
overweight /
obese children and adolescents aged between 10 and 18 years . -
pubmed
Vaccination for
smallpox in
humans and
rinderpest in
cattle was the basis for disease eradication , and recent progress in
polio eradication is promising . -
pubmed
Then , chronic administrations of
HD0471953 were performed to evaluate the efficacy on various
diabetic rodent models . -
pubmed
The results suggest that
HD0471953 may be a potentially promising anti -
hyperglycemic agent for the treatment of
patients with
type 2 diabetes mellitus . -
pubmed
CKD patients are at high risk not only for
end - stage renal disease , but also for
cardiovascular disease ,
infection ,
malnutrition , and other comorbid conditions frequently associated with the elderly population . -
pubmed
Sleep fragmentation and
increased periodic limb movements are more common in
children with
nocturnal enuresis . -
pubmed
METHODS : Paediatricians assessed NE parameters in
children referred to an
enuresis clinic . -
pubmed
RESULTS : The study group comprised 67
children with proven
NE ( 50
boys and 17
girls between six and 16 years : 11.1 + - 2.8 SD ) . -
pubmed
Children with
NE had a higher incidence of periodic limb movements associated with cortical arousals in their sleep . -
pubmed
CONCLUSION :
Children with
NE displayed higher
sleep fragmentation and periodic limb movements in sleep than the control
children with a possible
sleep disorder without
NE . -
pubmed
Urinary
polycyclic aromatic hydrocarbon metabolites and
attention / deficit hyperactivity disorder ,
learning disability , and special education in U.S.
children aged 6 to 15 . -
pubmed
The balance was measured by Berg Balance Scale ( BBS ) , Postural Assessment Scale for
Stroke Patients ( PASS ) , and Functional Reach Test ( FRT ) . -
pubmed
Understanding this
dysbiosis is challenging because of the extraordinary complexity of the gut ecosystem and the tremendous variability between healthy individuals in the taxa that make up the
human microbiome . -
pubmed
PURPOSE : Postpneumonectomy
empyema (
PPE ) is a possible complication after a pneumonectomy in
patients with
lung cancer . -
pubmed
Recurrence of
PPE within 6 months of initial PPE resolution occurred in 28 % of
patients . -
pubmed
Crocin ( a
carotenoid isolated from
saffron ) , has protective effects against
DZN cardiotoxicity . -
pubmed
METHODS :
Rats were divided into 7 groups :
corn oil ( control ) ,
DZN ( 15 mg / kg / day , gavage ) ,
crocin ( 12.5 , 25 , 50 mg / kg / day , i. p. ) plus
DZN ,
vitamin E ( 200 IU / kg , i. p. , 3 days a week ) plus
DZN and
crocin ( 50 mg / kg / day , i. p. ) . -
pubmed
Prostatic urethral lift improves urinary symptoms and flow while preserving sexual function for
men with
benign prostatic hyperplasia : a systematic review and meta - analysis . -
pubmed
Repair of acute
type A aortic dissection in
comatose patients . -
pubmed
The DNA G+C content of
strain JC234 T was 54.3 mol % . -
pubmed
The type
strain is
JC234 T ( = KCTC 42071 T = LMG 28200 T ) . -
pubmed
SUBJECTS : Two hundred thirty adult male
Sprague - Dawley rats weighing 280 - 320 g. INTERVENTIONS :
Subarachnoid hemorrhage was induced in
rats by endovascular
perforation . -
pubmed
Nussenzweig and colleagues evaluate
genomic instability and germinal center derived lymphomagenesis in
mice infected with Plasmodium to recreate some of the hallmark characteristics of
Burkitt lymphoma , a form of
cancer more common in parts of Africa where
malaria is endemic . -
pubmed
We describe a
patient with
acute kidney injury due to
glomerular bleeding and
tubular injury related to severe
thrombocytopaenia , who was subsequently found to have
thin basement membrane disease . -
pubmed
CASE PRESENTATION : A 56 year old
man presented with macroscopic
haematuria ,
acute kidney injury and a platelet count of 35 x 10(9)/L , in the absence of anticoagulation . -
pubmed
At 9 months , the
patient progressed to Stage 5
chronic kidney disease with the development of gross
renal atrophy . -
pubmed
CONCLUSION : Recurrent macroscopic
haematuria may be a risk factor for progressive
renal injury in
patients with thin basement membrane . -
pubmed
In the absence of anticoagulation , severe
thrombocytopaenia may be a risk factor for heavy
glomerular bleeding and
acute kidney injury in these
patients . -
pubmed
Restricted temporal access to food and
anorexia in
mice : Microstructure of eating within feeding opportunities . -
pubmed
Intake and
body weight were recorded in a closed economy as male and female C57BL/6
mice progressed through either fixed interval ( FI ) or fixed unit price ( FUP ) schedules of cost for 20 - mg food pellets . -
pubmed
In the FI protocol ,
mice maintained adequate food intake and
body weight through the study , even though at the highest FI ( 50 - s ) they spent the entire 40 - min FOs engaged in eating at or near the maximum rate allowed by the schedule . -
pubmed
We discuss the role of effort or time in
FUP - induced
anorexia , and suggest this
murine model may emulate some aspects of
human anorexia nervosa better than current activity - based protocols . -
pubmed
Osteosarcoma is the most frequent primary
malignant bone tumor that occurs in
children and
adolescents . -
pubmed
The present study aimed to identify novel therapeutic strategies for
osteosarcoma , by assessing the antitumor activity of the cannabinoid
WIN-55,212 - 2 and its combined effect with
adriamycin (
ADM ) against the
MG-63 human osteosarcoma cell line . -
pubmed
Over - drainage and persistent shunt - dependency in
patients with
idiopathic intracranial hypertension treated with shunts and bariatric surgery . -
pubmed
METHODS : The study cohort includes 13
patients with
IIH that underwent shunt surgery for treatment of the IIH - related symptoms . -
pubmed
CONCLUSIONS :
Patients with
IIH that undergo shunt surgery and BS ( not concomitantly ) may suffer from OD symptoms , necessitating multiple shunt revisions , and valve upgrades . -
pubmed
Resident
workers and soldiers were age - matched with unfamiliar worker stimulus
animals as intruders , and encounters were videorecorded and scored for
aggressive behaviors . -
pubmed
These data suggest that in naked mole -
rats OT promotes prosocial behaviors rather than
aggression and that even within subordinates status exerts robust effects on brain and behavior . -
pubmed
Final components of the TB /
HIV electronic medical records system include : patient demographics ; anthropometric measurements ; laboratory samples and results ; HIV testing ; WHO clinical staging ;
TB diagnosis ; family planning ; clinical review ; and drug dispensing . -
pubmed
RESULTS : Our experience suggests that an electronic medical records system can improve patient management , enhance integration of
TB /
HIV services , and improve provider decision - making . -
pubmed
CASE DESCRIPTION : A 68 - year - old
man presented with
cerebral infarction due to an
artery - to - artery embolism from the
right cervical ICA stenosis . -
pubmed
BACKGROUND :
Snakebite incidence in southwestern China is mainly attributed to one of the several venomous snakes found in the country , the
white - lipped green pit viper Trimeresurus albolabris . -
pubmed
Resolution of
left ventricular postinfarction thrombi in
patients undergoing percutaneous coronary intervention using
rivaroxaban in addition to dual antiplatelet therapy . -
pubmed
Left ventricular ( LV )
thrombus is usually seen in situations with reduced LV function , and is mostly seen in
patients with large
anterior ST - elevation myocardial infarction (
MI ) . -
pubmed
Most embolic events , in
patients with LV
thrombus formation , occur within the first 3 - 4 months , thus the recommendations regarding the duration of anticoagulant therapy . -
pubmed
Novel oral anticoagulants were found to be either non - inferior or superior compared with
warfarin in prevention of
thromboembolism in
patients with non - valvular
atrial fibrillation . -
pubmed
Here , we report on the dissolution of LV apical
thrombus in 3
patients with anterior ST - elevation
MI receiving dual antiplatelet therapy and
rivaroxaban on a reduced dose for 3 months . -
pubmed
STUDY DESIGN : We retrospectively reviewed 158
children with
precursor B - cell type ALL who were followed up for & gt;2 years . -
pubmed
Intensive evaluations for
hematologic malignancies may be unnecessary in
children who complain of
limb pain without any definite cause , unless they also present with accompanying
leukemic symptoms . -
pubmed
Comparing samples from femoral heads harvested from 11
patients and 11 cadaveric controls , we show that the mineral and organic chemical composition of trabecular bone in
ON is not modified apart from age - related differences . -
pubmed
RESULTS : Two
patients ( 1.4 % ) developed
postoperative complications requiring redo surgery . -
pubmed
CONCLUSION : The ELAR technique with mesh augmentation is an innovative , minimally invasive surgical procedure for treatment of
patients with a complex
abdominal wall hernia comprising symptomatic umbilical , trocar , and/or
epigastric hernias with concomitant
rectus abdominis diastasis . -
pubmed
Brucellosis is regarded as one of the most common diseases among
humans and livestock . -
pubmed
The present case - study was carried out on 40
patients with
brucellosis ( case ) and 20 healthy people ( control ) . -
pubmed
Moreover , the present study indicated that
brucellosis produces oxidative stress in
patients . -
pubmed
Subsequent maternal separation exacerbates
neurobehavioral abnormalities in
rats neonatally exposed to
sevoflurane anesthesia . -
pubmed
Several recent studies suggest that in the
human population , a routine , short anesthetic in otherwise healthy infants is void of
neurodevelopmental insult . -
pubmed
On the other hand , many
human retrospective epidemiological studies report evidence of
cognitive abnormalities in
children after testing those who had different anesthesia - requiring procedures in early childhood . -
pubmed
Despite posing a challenge for the unsuspecting physician , an early diagnosis of
granulomatous mastitis improves
patient outcomes . -
pubmed
Potential Impact of Metabolic and Gut Microbial Response to Pregnancy and Lactation in Lean and Diet - Induced
Obese Rats on Offspring
Obesity Risk . -
pubmed
METHODS AND RESULTS : 1 H NMR serum metabolomics analysis was performed on samples collected pre - pregnancy and in pregnant and lactating lean and high fat /
sucrose ( HFS ) diet - induced
obese Sprague - Dawley rats to identify maternal metabolic pathways associated with developmental programming of offspring
obesity . -
pubmed
A case of
empyema and
septic arthritis due to
Nocardia farcinica . -
pubmed
There is paucity of information on how
glaucoma affects the quality of life of
patients in low and middle - income countries where resources for both diagnosis and treatment of such conditions are limited . -
pubmed
In this study we investigate the impact of
glaucoma on quality of life in Ethiopian
patients . -
pubmed
METHODS : The quality of life of 307
glaucoma patients and 76 normal controls that were frequency matched to the age and sex profiles of the cases was assessed using Amharic version of Glaucoma Quality of Life -15 questionnaire . -
pubmed
PATIENT CONCERNS : This is the case of a 73 - year - old
man who reported to the Clinic of Cranio - Maxillofacial and Oral Surgery and Implantology , Medical University of Warsaw , owing to a
skin tumor in the right parotideomasseteric region , initially diagnosed as
discoid lupus erythematosus . -
pubmed
INTERVENTIONS : The
patient was transferred to the
Lymphoid Tumours Clinic of the Maria Sklodowska Curie Memorial Cancer Centre and Institute of Oncology in Warsaw , where chemotherapy was initiated . -
pubmed
Misdiagnosis can lead to inappropriate therapy and result in
disease progression or unnecessary harm to the
patient . -
pubmed
This study investigated whether early signs of
attention deficit hyperactivity disorder (
ADHD ) in
toddlers aged 2 - 3 years are associated with disturbed sleep and activity levels . -
pubmed
Comparison of conservative exercise therapy with and without Maitland Thoracic Manipulative therapy in
patients with
subacromial pain : Clinical trial . -
pubmed
OBJECTIVE : To determine the effect of conservative exercise therapy with and without Maitland thoracic manipulation in
patients with
subacromial pain . -
pubmed
METHODS : The randomised controlled trial study was conducted at the Mayo Hospital , Lahore , Pakistan , from June 2015 to February 2016 , and comprised
patients with
subacromial pain ( group 1 ) and controls ( group 2).Pre - assessment was done by using numeric
pain rating scale and shoulder
pain and disability index as subjective measurements , while range of motion was taken as objective measurement . -
pubmed
Moreover , heart /
body weight ratio and ventricular interstitial
fibrosis were increased in TAC - operated WT
mice compared with that of sham - operated WT
mice . -
pubmed
However , there are still relatively few studies about circadian rhythms in
neuromyelitis optica spectrum disorders (
NMOSD ) and 2D2 transgenic
mice . -
pubmed
2D2
mice might be a suitable model for studying circadian disruption in
NMOSD . -
pubmed
Here , we describe the synthesis of
( E )- 2 - isopropyl-5 - methyl-4 -(( 2 -( pyridin-4 - yl ) hydrazono ) methyl ) phenol ( 18 ) , which binds
ferriprotoporphyrin - IX (
FeIII - PPIX ) ( Kd = 33 nM ) and offers antimalarial activity against
chloroquine - resistant and sensitive
strains of
Plasmodium falciparum in vitro . -
pubmed
berghei ANKA ( causing
cerebral malaria ) in
mice with negligible toxicity . -
pubmed
Human dermal fibroblast is essential in
wound healing of the skin through the synthesis of extracellular matrix proteins . -
pubmed
Remifentanil treatment increased the proliferation of
human dermal fibroblast and decreased apoptotic cell
death , enhancing autophagic activity under oxidative stress . -
pubmed
This study demonstrates that
remifentanil activated autophagy and decreased apoptotic
death of
human dermal fibroblasts under oxidative stress . -
pubmed
PARTICIPANTS : Thirty - one
individuals ( 21
men and 10
women ; mean age , 60 years ) , who had
poststroke hemiparesis . -
pubmed
BACKGROUND : Although accumulated evidence provides a strong scientific premise for using immune profiles to predict survival in
patients with
cancer , a universal immune profile across
tumor types is still lacking , and how to achieve a survival - associated immune profile remains to be evaluated . -
pubmed
Intriguingly , this immune profile transformation led to inhibition of
metastasis and to prolonged survival in both
mouse and
patient - derived xenograft malignant models . -
pubmed
Impacts of
Escherichia coli infection in young breeder
chicks on the behavior and cerebral activity of purinergic and cholinergic enzymes involved in the regulation of molecules with neurotransmitter and neuromodulator function . -
pubmed
Macroscopically ,
pericarditis and
hepatic congestion were observed in the birds , but without histopathological lesions in the encephalon although the bacterium was present in the cerebral cortex of all
animals in the infected group ( i.e. -
pubmed
Gluten , a group of proteins found in
wheat ,
barley , and
rye , is the trigger of
celiac disease , an
immune disorder that affects about 1 % of
people worldwide . -
pubmed
TNBC patient prognosis , survival and response to current therapies are poor and for this reason it is crucial to search new therapeutic targets in
TNBC to develop new therapeutic strategies . -
pubmed
METHODS : In a cross - sectional study , 18
PD patients ( 13 M/5F , 64 + - 7 years , range 46 - 74 years , disease duration 2.9 + - 2.6 years ; UPDRS motor 21.9 + - 5.2 ) and 20 age- and gender - matched healthy control ( HC )
subjects ( 15 M/5F , 61 + - 7 years , range 50 - 72 years ) were included . -
pubmed
In a subsequent longitudinal phase , ten of the
PD patients ( 7 M/3F , UPDRS motor 20.6 + - 6.9 ) underwent a second PET measurement after 18 - 24 months . -
pubmed
RESULTS : The univariate region - based analysis showed no differences in SERT levels when the
PD patients were compared with the HC neither at baseline or after 2 years of follow - up . -
pubmed
CONCLUSION : We conclude that the serotoninergic system in
PD patients seems to become involved with a network dysregulation as the disease progresses , suggesting a disturbed serotonergic signaling from raphe nuclei to target subcortical and cortical regions . -
pubmed
Patients with
prolactinoma , corticotroph
adenoma , and
Rathke ' s cleft cyst had small sellar masses ( < 1 centimeter ) while the majority of patients with other
SMs had
macroadenomas . -
pubmed
Hypogonadism and
growth hormone deficiency was present in 41.8 % and 20.5 % of the
patients , respectively . -
pubmed
BACKGROUND :
Patients with
focal segmental glomerulosclerosis (
FSGS ) characterized by
steroid - resistant
nephrotic syndrome (
SRNS ) are prone to progress to
ESRD . -
pubmed
Mechanism for the
FSGS patients ' response to
steroid treatment is still unknown and currently , it is impossible to predict the
steroid resistance before treatment of
patients with
FSGS . -
pubmed
METHODS : To identify biomarkers and potential therapeutic targets of
FSGS patients with
SRNS ,
patients diagnosed as kidney biopsy - proven
FSGS and
nephrotic syndrome (
NS ) were prospectively enrolled . -
pubmed
Additionally , the system was capable of penetrating
human skin beyond the stratum corneum , which enhances the potential of these nanoclusters as bifunctional photodynamic therapy effectors and biomarkers with application in a diversity of
skin diseases . -
pubmed
Three species accounted for around 60 % of the
strains :
F. - pubmed
OBJECTIVE :
Patients with
unilateral deafness and residual hearing on the contralateral ear can benefit from a cochlear implant ( CI ) on one side and a hearing aid ( HA ) on the other . -
pubmed
In this focused and histology - guided study , tissue from a
patient diagnosed with aggressive
BCC was analyzed by imaging mass spectrometry in order to probe the chemistry of the complex
tumor environment . -
pubmed
Comparison of the long - term efficacy between
tenofovir and
entecavir in
chronic hepatitis B patients . -
pubmed
Oropharyngeal cancer is a subtype of
head and neck squamous cell carcinoma that is associated with unique risk exposures like consumption of smokeless
tobacco and
areca nut and is highly prevalent in the northeastern region of India , especially Meghalaya . -
pubmed
HPV DNA sequences were not detected in any of the
tumor samples in RNA - Seq data . -
pubmed
Introduction : Various studies are being conducted because of the value of finding an appropriate medication to control
bleeding in
patients with
epistaxis faster and more conveniently . -
pubmed
Methods : This randomized clinical trial enrolled
patients with
epistaxis presenting to the emergency departments of two hospitals affiliated to Tabriz University of Medical sciences . -
pubmed
Primary outcome variables included
bleeding control time and
patient satisfaction . -
pubmed
Results :
Epistaxis was controlled in less than 5 minutes in 85 ( 79.4 % )
patients in the intervention group and 85 ( 88.5 % )
patients in the control group ( P=0.058 ) . -
pubmed
In the intervention group , 10
patients experienced
recurrence of
epistaxis within 24 hours of treatment , while 9
patients in the control group experienced
recurrence ( P= 0.591 ) . -
pubmed
Conclusion : Based on the findings ,
bleeding control time was similar in the two groups , but
patient satisfaction was higher in Traumastem group . -
pubmed
The clinical utility of computed tomographic scanning and neurologic examination in the management of
patients with minor
head injuries . -
pubmed
To validate this hypothesis we studied 2766
patients with an isolated
MHI admitted to seven
trauma centers between January 1 , 1988 , and December 31 , 1991 . -
pubmed
There were 1898 male
patients and 868 female patients ;
injury was blunt in 99 % . -
pubmed
Occurrence of
cataracts in
triploid Atlantic salmon (
Salmo salar ) on four farms in Scotland . -
pubmed
In September 1991
cataracts occurred in two year - classes of
triploid Atlantic salmon . -
pubmed
During the period mentioned above there ware hospitalized 54
patients having
epibulbar tumours . -
pubmed
The anatomopathological exam which was effectuated for 33
patients he s shown Bowen 's disease for 14 cases , spinocellular
carcinoma for 15
patients and basocellular for 3
patients . -
pubmed
There was
retinoblastoma for 19 cases ; it had been practiced the enucleation of ocular globe for 17
patients and for two cases it had been practiced the exenteration of the eye socket . -
pubmed
The hepatic scintigraphy was practiced for 56
patients and had shown for 8 cases hepatic
metastasis . -
pubmed
We have attempted to define the synergistic interaction between immuno- and chemotherapy further , using the
murine irradiated vaccine model of
schistosomiasis mansoni . -
pubmed
[
Eosinophilia and
giardia lamblia intestinal parasitism ] . -
pubmed
[ Binding of ( 3)-
imipramine by platelets from spontaneously
hypertensive , normotensive , and
Wistar rats and their behavior in stressful situations ] . -
pubmed
Spontaneously
hypertensive rats ( SHR ) , when submitted to stress remained active during both avoidance ( water escape task test ) and nonavoidance ( forced swimming test ) stress - situations . -
pubmed
Wistar rats responded to a
depression of active behaviour in forced swimming test and difficulty at resolving of complicated problem in water escape task test . -
pubmed
Effect of intrinsic sympathomimetic activity on the ability of
hypertensive patients to derive a cardiorespiratory training effect during chronic beta - blockade . -
pubmed
The effect of intrinsic sympathomimetic activity ( ISA ) on the ability of
patients with
high blood pressure ( BP ) to derive a cardiorespiratory training effect during long - term beta - blocker therapy was studied . -
pubmed
Fifty sedentary
hypertensive subjects were randomly assigned to
propranolol ( n = 23 ) or
pindolol ( n = 27 ) therapy for a 22 week double - blind parallel study . -
pubmed
Five normal subjects and 10
patients , of whom 5 presented
esophageal achalasia and 5
gastroesophageal reflux disease , underwent computerized esophageal manometry and were evaluated on the basis of both traditional and innovative parameters , of our own inception . -
pubmed
In both adults and children , postassault
infections with viral agents of
STDs , including
herpes simplex viruses ,
hepatitis B virus , and
human immunodeficiency virus , have been described . -
pubmed
To test the effects of chronic
hypoxia without an antecedent
hyperoxic injury in the kitten , the
animals were raised in 13 % or 21 % ( room air )
oxygen and their retinas examined at 3 , 7 , 14 , or 21 days . -
pubmed
Effect of
DMBA on
oral cancer development in
hamsters with latent
HSV-1 infections in trigeminal ganglia . -
pubmed
This study examined the effect of
7 , 12 - dimethyl - benz ( a ) anthracene (
DMBA ) ,
polycyclic aromatic hydrocarbon carcinogen , on pathologic changes in buccal pouch mucosa of
hamsters with latent
herpes simplex virus type 1 ( HSV-1 ) infections in their trigeminal ganglia . -
pubmed
Of the pouches receiving
DMBA , the average cumulative
tumor diameter ( the sum of the
tumor diameters in each group divided by the number of pouches in that group ) was notably greater in animals with latent
HSV-1 than in animals that had not been infected ; however , this difference was not significant . -
pubmed
The
DMBA - treated
hamsters that had latent
infections also displayed a higher severity and prevalence of histopathologic changes in their pouch mucosa . -
pubmed
This study indicates that latent
HSV-1 and
DMBA show synergism in the development of
tumors and precancerous histopathologic changes in
hamster buccal pouch mucosa . -
pubmed
Of the 35
subjects with
DS , 16 had values of 60 - 84 micrograms / dl ( mean 74.25 + /- 8.29 micrograms / dl ) ( table I ) , which are well below normal . -
pubmed
Out of 16
patients with low
zinc values 10 ( 68.5 % ) were particularly susceptible to
infections . -
pubmed
In
hypothyroid rats , endotoxin administration increased the rates of glycolysis in muscle in vitro . -
pubmed
Ventricular dysfunction induced by
dipyridamole would be evidence of
myocardial ischemia in
patients with limited ability to undergo standard exercise testing . -
pubmed
Among these
patients , 21 ( 68 % ) had significant
coronary artery disease ( greater than or equal to 50 % stenosis ) , 19 ( 61 % ) had severe
coronary disease ( greater than or equal to 70 % stenosis ) and 10 ( 32 % ) were " normal " ( less than 50 % stenosis ) . -
pubmed
However , in
patients with
coronary artery disease , the ejection fraction failed to increase during exercise or after
dipyridamole . -
pubmed
In the
patients with
coronary artery disease , regional wall motion decreased by 4.1 + /- 0.5 units during exercise ( p less than 0.003 ) and by 1.8 units after
dipyridamole ( p less than 0.02 ) . -
pubmed
Specific subsets of
patients with severe
coronary atherosclerosis were analyzed with use of these criteria . -
pubmed
In
patients with severe
stenosis ( greater than or equal to 70 % ) , the sensitivity of
dipyridamole ventriculography was 67 % compared with 89 % for exercise ventriculography . -
pubmed
This technique provides a widely applicable , useful alternative to exercise ventriculography in the diagnosis of
coronary atherosclerosis in
patients who have limited exercise tolerance . -
pubmed
The use of this technique is demonstrated for the cloning of a sequence from within the
human alpha -
globin complex that was previously shown to be " unclonable " in bacteriophage and cosmid vectors and which is a multiallelic general genetic marker , as well as both beta -
globin alleles from an
individual with
beta - thalassaemia . -
pubmed
Haldane himself rejected the simple explanation that males are innately more sensitive than females to the effects of hybridization because groups with heterogametic females ( such as
birds and
butterflies ) usually show
female sterility in hybrids , so that heterogamety itself is the critical feature . -
pubmed
Light sensitivity of the central and peripheral parts of the
human retina has been studied in an hour exposure to broadband noise of 95 dBA intensity and in an after - effect period . -
pubmed
[
Refractive errors among
children . -
pubmed
Emergency management of unexpected
defects of hemostatic function in surgical
patients . -
pubmed
Nondialysable
sugar - peptide fraction in the plasma of
diabetic patients . -
pubmed
Vomiting and
wasting disease in
piglets . -
pubmed
[ Action of
reserpine and of one of its derivatives on compensatory
ovarian hypertrophy in the female
rat ] . -
pubmed
Nature of immunity to
Newcastle disease in vaccinated
chickens . -
pubmed
[ Experience in saving 8
patients with
ventricular tachycardia ] . -
pubmed
An experimental model in
rats was developed to define the nature of humoral and cellular factors that contribute to impaired immune responsiveness in
chronic renal failure . -
pubmed
Addition of uremic
rat serum to both normal and
uremic lymphocytes significantly suppressed cellular responses , the suppression being more pronounced with uremic lymphocytes . -
pubmed
Thus the effect on antibody response in
uremic animals is dependent upon the antigen tested . -
pubmed
[
Atrial septal defect in 3
patients over 70 years of age ] . -
pubmed
From March 1971 to September 1973 , 200
patients with primary
bronchogenic carcinoma received 4,000 rad ( 40 Gy ) by means of split - course accelerated fractionation . -
pubmed
Forty - five
patients ( 22.5 % ) survived more than 11 months ; and of these , 6 ( 13.3 % ) were found to have progressive
myelitis . -
pubmed
Zinc and
copper levels in plasma , erythrocytes , and whole blood in
cancer patients . -
pubmed
Zinc and
copper levels in erythrocytes , plasma , and whole blood were determined in 35
cancer patients and compared with 24 normal individuals . -
pubmed
A decrease in
zinc was found in all three blood constituents of the
cancer patients . -
pubmed
Further investigations are indicated to determine whether these two elements could serve as indicators for diagnosis or prognosis in
cancer patients . -
pubmed
The first patient had no antecedent
ear disease and developed a large Bezold
abscess caused by
Fusobacterium varium . -
pubmed
This patient developed
labyrinthitis and
meningitis due to
B. - pubmed
Thirty - two young
athletes ( ages ranging from 17 to 30 years ) with a clinical diagnosis of a symptomatic
lumbar disc and
sciatica were treated with lumbar epidural
cortisone injections . -
pubmed
The serum levels and urinary excretion of
magnesium and
copper were studied in 66
patients with either acute
myocardial ischemia or
myocardial infarction . -
pubmed
The initial serum
magnesium levels were normal in
patients with
ischemia but were low in some
patients with
myocardial infarction . -
pubmed
Patients developing
ventricular arrhythmias with
myocardial infarction showed the lowest levels of serum
magnesium . -
pubmed
Copper in the serum appeared elevated in
patients developing acute
congestive heart failure but the elevation was not statistically significant . -
pubmed
These data indicate that a decrease in serum
magnesium as evaluated may be associated with
ventricular arrhythmias in
patients with
myocardial infarction ; thus continued observations of
magnesium levels in the
myocardial infarction patient is warranted . -
pubmed
MATERIALS AND METHODS : A review of all arthroscopic reports from two institutions during the periods 1990 - 1992 and 1992 - 1993 , respectively , revealed 13
patients with partial
tears of the ACL . -
pubmed
BACKGROUND :
Renal cell carcinoma is a frequent cause of morbidity and mortality in
patients with
von Hippel - Lindau disease . -
pubmed
METHODS : A review was conducted of 10
patients with
von Hippel - Lindau disease and localized
renal tumors , who underwent renal parenchyma - sparing surgery . -
pubmed
Four
patients had
recurrences , requiring a total of 16 operations . -
pubmed
Patients were followed for
recurrence by computed tomography . -
pubmed
Of the 10
patients , 2 died , one of primary
lung cancer with recurrent
renal cell carcinoma found at autopsy , and one of metastatic
renal cell carcinoma . -
pubmed
The other seven
patients were alive and without evidence of
renal cancer . -
pubmed
CONCLUSION : Although the risk of
recurrence is high , these
patients may be treated with parenchyma - sparing renal surgery and enjoy a prolonged survival , and avoid the complications of dialysis or transplantation . -
pubmed
A 26 - year - old
woman with
mononeuropathy multiplex complained of severe
pain of right foot and
ipsilateral steppage gait . -
pubmed
This is the first report of a
patient with
NSN showing positive ANCA . -
pubmed
Histopathology of the small intestinal mucosa in Nematodirus spathiger
infection in
rabbits . -
pubmed
These distal variations were similar to those previously described in experimental
Trichostrongylus colubriformis infections of
rabbits . -
pubmed
These results tend to confirm the use of the
rabbit as an experimental model to study
Nematodirus infection . -
pubmed
The objective of this article is ( 1 ) to review the range of
anterior segment ocular disease caused by
varicella - zoster virus (
VZV ) , ( 2 ) to discuss the pathophysiology of the mechanisms involved in the ensuing tissue damage , and ( 3 ) to bring the reader up to date on the current management and therapy of
herpes zoster ophthalmicus (
HZO ) . -
pubmed
Diagnostic testing for
dementia in
patients with
Parkinson ' s disease . -
pubmed
We describe the case of a
patient who presented with recurrent acute
hemarthrosis after anterior cruciate ligament reconstruction without additional
trauma and without instability . -
pubmed
White matter MR hyperintensities in adult
patients with
congenital rubella . -
pubmed
PURPOSE : To observe and quantify
white matter hyperintensities on MR images in
adults with
schizophrenialike symptoms who had had
congenital rubella , in order to elucidate the neuropathologic sequelae of this perinatal
viral infection and to explore the potential relationship of these lesions to
schizophrenia . -
pubmed
METHODS : Eleven deaf adult
patients with documented
prenatal rubella virus infection and schizophrenialike symptoms were compared with 19 age - matched
patients with early - onset
schizophrenia who did not have
congenital rubella and with 18 age - matched control subjects . -
pubmed
RESULTS : Ratings of
white matter lesions were significantly higher in the
rubella patients than in the control subjects : 6 of the 11
patients had ratings greater than 1 compared with 1 of the 18 control subjects and none of the 19
schizophrenic patients . -
pubmed
Also , MR images in five
rubella patients received ratings at the highest end of the scale of abnormality ( 3 or 4 ) . -
pubmed
Effect of combination therapy with lipid - reducing drugs in
patients with
coronary heart disease and " normal "
cholesterol levels . -
pubmed
BACKGROUND : Combination drug therapy has been shown to decrease
cholesterol levels in
hyperlipidemic patients . -
pubmed
Social phobia in disabled
workers with chronic
musculoskeletal pain . -
pubmed
Most
patients were had been taking
benzodiazepines because of
panic disorder or
neurosis . -
pubmed
During the withdrawal the
patients were rated daily for
anxiety ,
mood alterations , perception disturbances ,
neurological symptoms , and vegetative signs . -
pubmed
Most
patients showed
sleep disturbances ,
mood alterations or
anxiety . -
pubmed
Because
anxiety , the reason for the
benzodiazepine treatment in many cases , often recurs , the
patients must be offered continuous after - care to prevent a new dependence . -
pubmed
Some of the new insights on the origins of radiation induced
chromosome aberrations in
human ,
mouse and
Chinese hamster , using FISH are reviewed in this paper . -
pubmed
The development of
gynecomastia in male
patients treated with
ketoconazole has led to investigation of its potent inhibitory effect on adrenal steroidogenesis . -
pubmed
In this study , we present our preliminary experience using high dose
ketoconazole , which was used safely as a palliative treatment in 3
patients with
Cushing ' s syndrome prior to surgery . -
pubmed
The most significant improvement of clinical symptoms was that the
patients could sleep much more comfortably at night following the suppression of
hypercortisolism by
ketoconazole . -
pubmed
In this study , the ictal phenomena of
dystonic limb posturing ,
tonic limb posturing , unilateral immobile limb , and version were distinguished and examined in
patients with
temporal and extratemporal seizures . -
pubmed
METHODS : Partial
seizures in 54
patients , successfully treated by surgery ( 34 temporal , 20 extratemporal ; 14 frontal , 3 parietal , and 3 occipital ) , were analyzed blindly by 3 reviewers . -
pubmed
RESULTS : In
patients with
temporal lobe epilepsy (
TLE ) ,
dystonic posturing occurred in 35.3 % ( kappa 0.78 , positive predictive value ( PPV ) for the sign being contralateral to
seizure onset 92 % ) ;
tonic limb posturing occurred in 17.7 % ( kappa 0.36 , PPV 40 % ) ; unilateral immobile limb occurred in 11.8 % ( kappa 0.23 , PPV 100 % ) ; and version occurred in 35.3 % ( kappa 0.77 , PPV 100 % ) . -
pubmed
In
patients with
extratemporal epilepsy ,
dystonic posturing occurred in 20.0 % ( kappa 0.31 , PPV 100 % ) ;
tonic limb posturing occurred in 15.0 % ( kappa 0.08 , PPV 67 % ) ; and version occurred in 40.0 % ( kappa 0.54 , PPV 100 % ) . -
pubmed
Reduced responsiveness of
rat mesenteric resistance artery smooth muscle to
phenylephrine and
calcium following
myocardial infarction . -
pubmed
The diagnosis in each case was very difficult , being mistaken with
tuberculosis in two of the
patients and with
paraneoplasic myelopathy in the other one . -
pubmed
A group of 87
patients suffering from unilateral
sudden hearing loss were investigated . -
pubmed
Twenty - five percent of the
patients had accompanying
vertigo . -
pubmed
Vertigo occurred more often in
patients with severe
hearing loss in high tone frequencies . -
pubmed
Hearing recovery of high tone frequencies was poorer in the
patients with
vertigo than in those without it , although the initial
hearing loss was the same . -
pubmed
The
chromosome aberration test using cultured
mammalian cells is one of the sensitive methods to predict environmental mutagens and/or carcinogens , and is a complementary test to the
Salmonella / microsome assay ( Ames test ) . -
pubmed
The selected viruses grew well on
Vero cells , but both mutants exhibited a growth defect on
swine macrophages at low multiplicities of
infection ( MOI ) , yielding 0.1 to 1.0 % of wild - type levels . -
pubmed
The Malawi TK deletion mutant showed reduced virulence for
swine , producing transient
fevers , lower
viremia titers , and reduced mortality . -
pubmed
Swine surviving TK-
ASFV infection remained free of clinical signs of
African swine fever following subsequent challenge with the parental pathogenic
ASFV . -
pubmed
Detection of
HPV-16 genome in
human oral cancers and potentially
malignant lesions from India . -
pubmed
The presence of high risk
human papilloma virus ( HPV ) 16 and 18 was examined in 100
oral cancer patients of Indian descent , 80 patients with potentially malignant
oral lesions and corresponding clinically
normal mucosa from 48 of these patients . -
pubmed
Additionally , presence of
HPV-33 , -6 and -11 was also studied in 86
oral cancers , 50 potentially malignant
oral lesions and 30 corresponding
normal oral mucosa . -
pubmed
HPV-16 was detected in 15 out of 100 ( 15 % ) oral
tumours , 27 out of 80 ( 34 % ) potentially malignant
lesions and 15 out of 48 ( 31 % ) of the corresponding
normal mucosa in the patients with
oral lesions . -
pubmed
HPV-18 was not detected in any of the
oral cancers ,
oral lesions and
normal mucosa . -
pubmed
HPV-33 and the low - risk
HPV-6 and -11 were also not detected in the
oral cancers , oral
lesions and corresponding
normal mucosa . -
pubmed
A significantly higher prevalence of
HPV-16 was observed in oral
lesions ( 27 out of 80 , 34 % ) as compared to
oral cancers ( 15 out of 100 , 15 % ) . -
pubmed
Our data indicates that
HPV-16 may play a direct role in a certain proportion of
oral cancers ; whereas in a subpopulation of
oral cancers HPV-16 infection may be vital in the early events associated with development of potentially malignant
oral lesions , and the presence of the virus not essential in the progression of the
oral lesion to frank
malignancy . -
pubmed
In
rats , the length of
lactational anovulation is prolonged when litter size is increased or when the dam is food restricted . -
pubmed
In
patients with sufficient bone height but insufficient bone width as a result of
tooth loss , a
jaw enlargement technique with osteotomes combined with soft tissue manipulation may be utilized to facilitate proper implant placement while concomitantly optimizing the aesthetics of the final implant prosthesis . -
pubmed
Re : orthotopic urinary diversion with preservation of erectile and ejaculatory function in
men requiring radical cystectomy for
nonurothelial malignancy : a new technique . -
pubmed
We compared early and late outcome of
patients with complex
coronary lesions in small vessel treated with traditional coronary angioplasty ( angioplasty group ) and with elective stent implantation ( stent group ) . -
pubmed
No
patients in the two groups experienced in - hospital
death or bypass surgery . -
pubmed
Myocardial infarction occurred in four
patients in the angioplasty group and in seven
patients in the stent group ( P = 0.36 ) . -
pubmed
No
patients in either the angioplasty or the stent group had acute stent
thrombosis , whereas subacute stent
thrombosis occurred in only one
patients of the stent group ( 0.9 % ) . -
pubmed
Lung transplantation has become a valid therapeutic option for
cystic fibrosis patients with
end - stage lung disease . -
pubmed
BACKGROUND :
Panic attacks can be induced in
persons with
panic disorder by inhalation of
carbon dioxide . -
pubmed
METHODS : Twelve
patients with
PD received
biperiden hydrochloride ( a muscarinic antagonist that crosses the blood - brain barrier ) ,
pirenzepine hydrochloride ( a muscarinic antagonist that does not cross the blood - brain barrier ) , or placebo 2 hours before a 35 %
carbon dioxide-65 %
oxygen respiratory challenge ( vs air as a placebo ) on 3 separate days , in a double - blind , random crossover design . -
pubmed
RESULTS : According to
patients ' self - ratings of subjective
anxiety , inhalation of the
carbon dioxide /
oxygen mixture provoked a significant and intense response after treatment with
pirenzepine and placebo . -
pubmed
We found that
infection by
cytomegalovirus (
CMV ) resulted in substantial increases in MIC on cultured fibroblast and endothelial cells and was associated with induced MIC expression in
interstitial pneumonia . -
pubmed
High - volume haemofiltration in
human septic shock . -
pubmed
PATIENTS : Eleven
patients with
septic shock and
multi - organ failure . -
pubmed
An apparent
hypersensitivity reaction (
bronchospasm and decrease in blood pressure ) had occurred during heart transplantation in a 59 - year - old
woman after intravenous infusion of
cyclosporine . -
pubmed
In previous studies , we synthesized two classes of electrophilic
tocopheryl quinones ( TQ ) , nonarylating
alpha - TQ and arylating gamma- and
delta - TQ , and found that gamma- and
delta - TQ , but not
alpha - TQ , were highly cytotoxic in
human acute lymphoblastic leukemia cells (
CEM ) and
multidrug - resistant ( MDR ) CEM / VLB100 . -
pubmed
We have now extended these studies on
tumor biology with
CEM ,
HL60 and
MDR HL60 / MX2 human promyelocytic
leukemia ,
U937 human monocytic
leukemia , and
ZR-75 - 1 breast adenocarcinoma cells . -
pubmed
Serial
dexamethasone suppression tests ( DST ) , obtained during a course of electroconvulsive therapy in 43 severely
depressed patients , did not exhibit relationships between the initial DST , final DST , or the change in DST with clinical outcome measures at the time of discharge . -
pubmed
We are unable to confirm a clinical application for the DST in the management of
patients during a course of
convulsive therapy . -
pubmed
PARTICIPANTS :
Patients were 51 neurologic intensive care
patients with an
intracranial disease requiring a central venous catheter due to the primary ( intracranial ) disease . -
pubmed
We excluded
patients under the age of 19 yrs and those with active
cardiac arrhythmia , full
sepsis syndrome ,
bleeding diathesis and
infection , or
bleeding at the site of the intended catheter insertion . -
pubmed
was comparable to the rate usually observed in our neurologic intensive care
patients with such severe
intracranial diseases . -
pubmed
One awake
patient (
subarachnoid hemorrhage , Glasgow Coma Scale score 15 ) experienced mild to moderate
shivering throughout the entire period of 7 days . -
pubmed
CONCLUSION : This novel intravascular cooling device ( Cool Line catheter and Cool Gard cooling device ) was highly efficacious in prophylactically controlling the body temperature of neurologic intensive care
patients with very severe
intracranial disease ( median Glasgow Coma Scale score , 3 - 15 ) . -
pubmed
Adrenal suppression in
asthmatic children receiving low - dose inhaled
budesonide : comparison between dry powder inhaler and pressurized metered - dose inhaler attached to a spacer . -
pubmed
OBJECTIVE : The purpose of this study was to evaluate the prevalence of
adrenal suppression in
children using low - dose
budesonide given by DPI , as compared with pMDI attached to a large - volume spacer device ( pMDI + spacer ) . -
pubmed
METHODS : In an open - labeled crossover study , 15
asthmatic children aged 5 to 15 years received 200 microg of inhaled
budesonide twice daily by DPI (
Turbuhaler , Astra , Draco AB , Lund , Sweden ) and by pMDI + spacer , 1 month each , in a randomized order . -
pubmed
CONCLUSIONS : Treatment of
asthmatic children with
budesonide 400 microg daily given via a
DPI for 1 month was associated with hypothalamic - pituitary - adrenal axis suppression . -
pubmed
Three
patients with carotid artery ( CA )
pseudoaneurysms were treated using four
polyethylene terephthalate endografts ( Wallgraft endoprostheses ) . -
pubmed
Two
patients received a single graft and one
patient with bilateral
pseudoaneurysms received two grafts . -
pubmed
Complete occlusion of the
pseudoaneurysm with patency of the arterial lumen was achieved following endograft placement in all
patients . -
pubmed
One
patient experienced neurological symptoms , and in - graft
stenosis ranging from 50 to 100 % occurred in three of the four grafts . -
pubmed
Although the Wallgraft endoprosthesis produced good initial results for the treatment of cervical CA
pseudoaneurysms , as demonstrated on radiography , it was associated with a high rate of
stenosis or occlusion in all three
patients . -
pubmed
OBJECTIVES : Despite clinical use , the radiosensitizing effect of
gemcitabine (
2'2 '- difluorodeoxycytidine ) in
human transitional cell carcinoma (
TCC ) has not been shown to date . -
pubmed
Examining responses of the local immune system of the brain in
neurocancer patients suggests that the immune system is involved in the neuroimmune interaction of both physiological and pathological conditions in the central nervous system ( CNS ) . -
pubmed
The vertical distribution of
Simulium damnosum bites on the
human body . -
pubmed
Liver transplantation in
patients with
intrahepatic stones : report of two cases . -
pubmed
METHODS : Liver transplantation was successfully performed for a 28 - year - old
man and a 42 - year - old
woman , both with
intrahepatic stones . -
pubmed
RESULTS :
Patient 1 had
digestive tract bleeding on the postoperative day 6 and he was discharged from the hospital on the postoperative day 25 . -
pubmed
Patient 2 also had
hemorrhage from the digestive tract on the postoperative day 44 and a leakage of end - to - side intestinal anastomosis on the postoperative day 47 . -
pubmed
CONCLUSION : Liver transplantation is safe and effective for
patients with
intrahepatic stones . -
pubmed
We previously reported that heteroplasmic point substitutions in the mitochondrial DNA D - loop were found in 15 of 75
children at risk for
mitochondrial disease ( vs 0/95 controls ) . -
pubmed
Gemcitabine and low dose
carboplatin in the treatment of elderly
patients with advanced
non - small cell lung cancer . -
pubmed
BACKGROUND : Fifty percent of
lung cancers arise in
patients over 65 years old and 30 % in those over 70 . -
pubmed
The aim of this study was to evaluate response , survival and tolerability of the combination
carboplatin -
gemcitabine in elderly
patients with advanced
non - small cell lung cancer (
NSCLC ) . -
pubmed
WHO grades 3 - 4 toxicities were :
neutropenia in 13 % of the cycles ,
thrombocytopenia and
anaemia in 4.5 and 14.7 % of
patients in any cycle . -
pubmed
CONCLUSIONS : The combination
carboplatin -
gemcitabine at these doses is feasible in elderly
patients with advanced
non - small cell lung cancer . -
pubmed
The
women in
dysfunctional labor had higher capillary
lactate and lower capillary
O ( 2 ) saturation . -
pubmed
OBJECTIVE : This study reviewed
patients with unilateral facial
paralysis and normal clinical and imaging findings who underwent diagnostic facial nerve exploration . -
pubmed
Study design and setting Fifteen
patients with facial
paralysis and normal findings were seen in the Mayo Clinic Department of Otorhinolaryngology . -
pubmed
RESULTS : Eleven
patients were misdiagnosed as having
Bell palsy or
idiopathic paralysis . -
pubmed
Progressive
facial paralysis with sequential involvement of adjacent facial nerve branches occurred in all 15
patients . -
pubmed
Seven
patients had a history of regional
skin squamous cell carcinoma , 13
patients had surgical exploration to rule out a
neoplastic process , and 2
patients had negative exploration . -
pubmed
CONCLUSIONS :
Patients with facial
paralysis and normal clinical and imaging findings should be considered for facial nerve exploration when the
patient has a history of
pain or regional
skin cancer , involvement of other cranial nerves , and prolonged facial
paralysis . -
pubmed
SIGNIFICANCE : Occult
malignancy of the facial nerve may cause unilateral facial
paralysis in
patients with normal clinical and imaging findings . -
pubmed
Topiramate is a novel anticonvulsant that may induce
weight loss in some
patients . -
pubmed
This is the first study to address the long - term efficacy and impact on weight of the combination of
olanzapine and
topiramate in
bipolar patients . -
pubmed
Twenty - six Diagnostic and Statistical Manual of
Mental Disorders , Fourth Edition
bipolar spectrum
patients received
olanzapine plus
topiramate cotherapy for treatment of their
manic ( n = 14 ) ,
hypomanic ( n = 6 ) ,
depressive ( n = 2 ) , and mixed ( n = 1 ) symptoms for 1 year . -
pubmed
RESULTS : The most constant responses in
adrenal incidentalomas were observed after stimulation by
terlipressin ( 18/20
patients , 28 - 415 %
cortisol increase ) and
cisapride ( 17/21
patients , 25 - 364 %
cortisol increase ) . -
pubmed
Chronic oral toxicity of a high gel point methylcellulose ( methocel HG ) in
rats and
dogs . -
pubmed
Verbal perseveration in
individuals with
Alzheimer ' s disease . -
pubmed
The study investigated the frequency of verbal perseveration in
individuals with
AD in relation to task type , mental status , and performance on attention and memory tests . -
pubmed
Early invasive strategy in elderly
patients with non - ST elevation
acute coronary syndrome : comparison with younger
patients regarding 30 day and long term outcome . -
pubmed
METHODS : All consecutive
patients admitted with a diagnosis of non - ST elevation
ACS from June 2002 to February 2004 were enrolled in this registry . -
pubmed
RESULTS : An early invasive strategy was followed for 439
patients , of whom 159 ( 36 % ) were elderly and had a higher clinical risk profile and greater extent of
coronary artery disease (
CAD ) than the younger
patients . -
pubmed
At a mean ( SD ) follow up time of 10.7 ( 5.2 ) months overall mortality ,
cardiac death , and
death plus
myocardial infarction were significantly higher among elderly
patients than among younger
patients ( 9.4 % v 2.1 % , p & lt ; 0.001 ; 6.8 % v 1.8 % , p & lt ; 0.01 ; 11.3 % v 5 % , p = 0.02 , respectively ) . -
pubmed
The significant difference in
cardiac death between the two groups was related more to elderly
patients being treated by coronary artery bypass grafting ( 19.3 % v 4.9 % , p = 0.05 ) than by percutaneous coronary intervention ( PCI ) ( 2.9 % v 1.1 % , p = 0.3 ) . -
pubmed
Kaplan - Meier analysis showed that
patients with
low beta - catenin expressing tumors trended toward worse 5 - year
disease - free survival ( P = 0.06 ) . -
pubmed
Of the 57
patients , 14 ( 24.6 % ) ( mean age , 70+/-4.6 years ) were diagnosed as having
gastroesophageal reflux disease with the use of conventional method . -
pubmed
After correction ,
gastroesophageal reflux disease diagnosis was made in 6 additional
patients ( mean age , 2.4+/-2.4 years ) and total number of
patients with
reflux increased to 20 ( 35.1 % ) ( p=0.031 ) . -
pubmed
Natural transmission of
Johne ' s disease to feral
goats . -
pubmed
Behavioural studies on the potential for direct transmission of
tuberculosis from feral ferrets (
Mustela furo ) and possums (
Trichosurus vulpecula ) to farmed livestock . -
pubmed
Tuberculous possums commonly and
tuberculous ferrets less commonly have
lung lesions and/or discharging
sinuses , and may excrete
Mycobacterium bovis intermittently or continuously in aerosols or discharges . -
pubmed
Patients with an index of 30 kg / m2 and under had a partial fat
necrosis rate of 11.4 percent ( 10 of 88
patients ) , whereas two of 19
patients ( 10.5 percent ) with an index of greater than 30 kg / m2 had partial fat
necrosis of their flap ( not significant ) . -
pubmed
The rate of non - flap - related complications , such as
deep venous thrombosis and
pulmonary embolism , was 8 percent ( seven of 88
patients ) for those with a
body mass index of less than 30 kg / m2 and 31.6 percent ( six of 19
patients ) for those with an index greater than 30 kg / m2 ( p = 0.0112 ) . -
pubmed
After above 10 - day treatment , all the
mice were killed and the
tumor body was taken out and weighed to calculate the inhibiting rates on
tumor . -
pubmed
RESULT : ( DFVP1 plus small dose of
CTX obviously enhanced the inhibiting rate of
CTX on
tumor in the
mice inoculated with
S180 cells . -
pubmed
Incidence of
chronic pain in
patients with
end - stage renal disease on dialysis . -
pubmed
A semiquantitative assessment of myocyte damage /
inflammation ( grading ) as well as of
fibrosis ( staging ) is indicated , thus providing histopathological diagnosis useful to the clinician for more appropriate
patient risk stratification and for the application of new therapies . -
pubmed
A cDNA microarray containing 9600 cDNA
spots was used to investigate differential expression of
human genes in oocyte , 4 - cell and 8 - cell embryos . -
pubmed
Most common pathogens of the
pyogenic liver abscess are
Escherichia coli ,
Klebsiella pneumoniae , Bacteroides ,
Enterococci ,
Streptococci , and
Staphylococci . -
pubmed
The patient was 52 years - old
man who had an episode of intermittent
fever ,
chills and
epigastric pain for 2 weeks . -
pubmed
[ Present situation and future perspectives of the epidemic of
HIV and
AIDS in Spain ] . -
pubmed
The rate of diagnoses of
HIV has fallen in both the indigenous population and immigrants ; however , demographic changes have meant an increase in the percentage of
HIV diagnoses in immigrants . -
pubmed
In homosexual men there have been descriptions of a recent increase in the incidence of
syphilis and gonococcus , which are a warning of possible increases in the transmission of
HIV in this group . -
pubmed
One third of the people who developed
AIDS in 2004 had not until then been diagnosed with
HIV , which prevented starting the antiretroviral treatment in time . -
pubmed
[ Hemodynamic effects of
levosimendan compared with
dobutamine in
patients with
low cardiac output after cardiac surgery ] . -
pubmed
However , experience with
levosimendan in
patients with
reduced cardiac output following cardiopulmonary bypass is limited . -
pubmed
METHODS : Forty - one
patients who had
low cardiac output after cardiopulmonary bypass were randomly assigned to
dobutamine ( n=20 ) , 24 - hour infusion of 7.5 microg / kg per min , or
levosimendan ( n=21 ) , at a loading dose of 12 microg / kg followed by 24 - hour infusion of 0.2 microg / kg per min . -
pubmed
Image relocation with prisms in
patients with age - related
macular degeneration . -
pubmed
BACKGROUND : To determine the benefits of image relocation ( IR ) with prisms in
patients with age - related
macular degeneration (
AMD ) . -
pubmed
METHODS : This was a retrospective comparative interventional case series of 100
patients with
AMD and 5 years of available follow - up records . -
pubmed
The present paper describes 22 cases of
chromoblastomycosis (
CBM ) caused by
Cladophialophora carrionii in children and adolescents ( 2 - 19 years old ) . -
pubmed
The
patients were thus able to avoid the evolution of the chronic , deforming and incapacitation clinical manifestations associated with
CBM . -
pubmed
Data from
patients with
noncancer or
cancer pain treated with TD
buprenorphine or TD
fentanyl for at least 3 months between May 2002 and April 2005 were analyzed . -
pubmed
RESULTS : In total , 631
patients with
noncancer pain and 605
patients with
cancer pain were included in the analysis ( 782
women , 454
men ; mean age , 76.3 years [ range , 29 - 100 years ] ) . -
pubmed
A significantly larger proportion of
patients receiving TD
buprenorphine had stable dosages over the entire treatment period compared with
patients receiving TD
fentanyl (
noncancer groups : 56.9 % vs 41.6 % ;
cancer groups : 50.0 % vs 26.2 % [ both , P & lt ; 0.05 ] ) . -
pubmed
Compared with TD
buprenorphine , the proportion of
patients with alternating dosage changes was significantly greater in
patients receiving TD
fentanyl (
noncancer groups : 22.7 % vs 13.1 % ;
cancer groups : 30.6 % vs 11.8 % [ both , P & lt ; 0.05 ] ) . -
pubmed
Herein , we report a rare case of
actinomycosis presenting as a
vocal cord nodule in a healthy 21 - year - old
man who was not immunocompromised and had no other known medical disease . -
pubmed
CONCLUSIONS : The high rates of
infection found in the populations studied presume a high risk of transmission , making it a priority to intervene in these groups to prevent the spread of
HIV and
STI . -
pubmed
Active surveillance for selected
patients with
renal masses : updated results with long - term follow - up . -
pubmed
Patients elected observation because of age , comorbidity ,
solitary kidney , or
bilateral renal masses . -
pubmed
A small but non - negligible risk of developing
metastatic disease exists in this
patient population . -
pubmed
With the recent advances in molecular biology and the ever - expanding understanding of
trauma pathophysiology , immunomonitoring in
trauma patients attempts to characterise and quantify novel molecules in order to predict
patients at risk . -
pubmed
This review article assesses the existing evidence on the biomarkers of
endothelial injury and their potential utility as quantification parameters of
endothelial dysfunction in
trauma patients . -
pubmed
Body balance in
patients with
systemic vertigo after rehabilitation exercise . -
pubmed
Physiotherapeutic procedures were carried out in a group of 12
people , aged 25 - 60 years suffering from
vertigo . -
pubmed
Patients with
vertigo underwent a month - long therapy , which included : exercise of motor - visual coordination on a posturographic platform and balance exercise , which consisted of repeated visual , vestibular , and somatosensory stimulation for conscious postural control . -
pubmed
Altered red cell membrane compositions related to functional
vitamin B ( 12 ) deficiency manifested by elevated urine
methylmalonic acid concentrations in
patients with
schizophrenia . -
pubmed
BACKGROUND : Abnormal cell membrane composition and functional
cobalamin (
vitamin B ( 12 ) ) deficiency was reported in schizophrenic
individuals . -
pubmed
We aimed to investigate the relationship between
cobalamin state and cell membrane composition in
patients with
schizophrenia . -
pubmed
METHODS :
Malondialdehyde (
MDA ) ,
cholesterol , and phospholipid classes in the erythrocyte membranes of 18
schizophrenic and 20 healthy
individuals of the same age and sex distribution were determined . -
pubmed
In
schizophrenic individuals ,
uMMA concentrations have a significant positive correlation with membrane
MDA and a negative correlation with membrane
cholesterol concentrations ( P<0.05 ) . -
pubmed
CONCLUSION : Our present findings suggest that , functional
vitamin B ( 12 ) deficiency representing itself by
MMA elevations in
schizophrenic individuals could damage cell membrane . -
pubmed
RATIONALE : Laboratory
animal and
human models of drug self - administration are used to evaluate potential pharmacotherapies for
drug abuse , yet the utility of these models in predicting clinically useful medications is variable . -
pubmed
CONCLUSIONS : The self - administration model has reliably identified medications to treat
opioid dependence , and the recent data with
modafinil suggest that the
human laboratory model also identifies medications to treat
cocaine dependence . -
pubmed
"
Torsade de pointes " during
amiodarone infusion in a
cirrhotic woman with a
prolonged QT interval . -
pubmed
We describe an interesting case of a
woman with decompensated
cirrhosis ,
ischaemic heart disease and
prolonged QT interval , who developed a new - onset
atrial fibrillation . -
pubmed
Our report underlines that the potential harmfulness of a
prolonged QT interval in cirrhotic
patients is currently not perceived in its entirety , so that various categories of drugs affecting ventricular repolarization are rather thoughtlessly used in clinical practice without monitoring the QT interval . -
pubmed
Thus ,
amiodarone should be avoided , if possible , or used with extreme care in
arrhythmic patients with advanced
liver disease . -
pubmed
Moreover , beta - blockers may be considered the first - line treatment for rate - control during
supraventricular tachyarrhythmias in cirrhotic
patients with delayed repolarization . -
pubmed
RESULTS : Nine
patients presented with ocular symptoms and one
patient experienced pulsatile
tinnitus . -
pubmed
In
patients with
penile cancer health - related quality of life is closely related to organ - sparing surgery . -
pubmed
MBL was absent in the lavage of all 7
children without
lung infection but present in 62 % ( 8/13 ) of those with acute
pneumonia /
pneumonitis , 23 % ( 5/22 ) with recurrent
respiratory tract infections , 17 % ( 1/6 ) with
primary ciliary dyskinesia and 8 % ( 3/37 ) with
CF ( p<0.01 ) . -
pubmed
Children with acute
pneumonia /
pneumonitis had significantly higher levels than those in the other groups . -
pubmed
OBJECTIVE : Approximately 50 % of
patients with
depression report symptoms of
pain , yet the clinical and biological mechanisms underlying this association remain unclear . -
pubmed
Similar to the general population , reported associations between
obesity and
insulin resistance in chronic
uremia support a role of adipose tissue and altered adipokine profiles in
insulin resistance in
obese chronic kidney disease patients . -
pubmed
MATERIALS AND METHODS : Fifteen
patients ( geometric mean 47 years , range 8 - 69 years ) with different types of
inflammatory arthritis of the finger or wrist joints participated in the study . -
pubmed
OBJECTIVE : To develop and validate a modified index for assessing the radiologic axial involvement in
psoriatic arthritis (
PsA ) in a group of
patients with established disease . -
pubmed
A 23 - year - old
man had been treated for repeated
pneumonia from the age of 16 . -
pubmed
Placental and fetal hemodynamics after
labetalol or
pindolol in a
sheep model of increased placental vascular resistance and maternal
hypertension . -
pubmed
We investigated the effects of
labetalol and
pindolol on uterine , placental , and fetal hemodynamics following
norepinephrine - induced maternal
hypertension in a
sheep model of increased placental vascular resistance . -
pubmed
The in vivo effect of the antibody was investigated in a
rabbit model of trabeculectomy by measuring the intraocular pressure ( IOP ) and
bleb area , and by immunohistological analysis of angiogenesis ,
inflammation , and
fibrosis . -
pubmed
MATERIALS AND METHODS :
Bladder ischemia was induced by ligation of bilateral vesical arteries in female
rats . -
pubmed
In
diabetic rats , the rate of leukocyte transmigration into the retinal tissues of live animals was significantly increased , as determined by AOLS . -
pubmed
However , firm adhesion of leukocytes in
diabetic animals treated with the inhibitor did not differ significantly from vehicle - treated
diabetic controls . -
pubmed
Genomic imprinting disorders in
humans : a mini - review . -
pubmed
The first report in
humans occurred in
Prader - Willi syndrome due to a paternal deletion of chromosome 15 or
uniparental disomy 15 ( both chromosome 15s from only one parent ) and similar
genetic disturbances were reported later in
Angelman syndrome . -
pubmed
Immunization of volunteers by the
bite of mosquitoes carrying radiation - attenuated
Plasmodium falciparum sporozoites protects greater than 90 % of such volunteers against
malaria , if adequate numbers of immunizing biting sessions and sporozoite - infected mosquitoes are used . -
pubmed
We tested the efficacy and
toxicity of a chemotherapy protocol consisting of
gemcitabine ,
5 - fluorouracil (
5 - FU ) and
leucovorin in
patients with inoperable or metastatic
pancreatic cancer , which was shown to improve median survival in a small phase II trial . -
pubmed
PATIENTS AND METHODS :
Patients older than 18 years of age with histologically or cytologically confirmed
adenocarcinoma of the pancreas and bidimensionally measurable disease , and who were chemotherapy- and radiotherapy - naive , were treated with a chemotherapy protocol consisting of
gemcitabine 1250 mg / m2 on day 1 , 5 - FU 450 mg / m2 and
leucovorin 100 mg / m2 on days 1 - 3 . -
pubmed
RESULTS : In an - intention - to - treat analysis , of 37
patients with
pancreatic cancer ( 27
males , 10
females ) ( 67.6 % stage IVb ) there were 7 ( 18.9 % ) objective partial responses ( 95 % confidence interval , 8.33 % to 29 ) , 14 ( 37.8 % )
patients had stable disease and 16 ( 43.2 % ) had progressive disease . -
pubmed
CONCLUSION : Despite our poor survival data , the combination of
gemcitabine with
5 -/ FU and
leucovorin is an active and well - tolerated regimen in
patients with
pancreatic cancer that merits further evaluation in prospective randomized studies . -
pubmed
Trajectories of
fatigue in
patients with
breast cancer before , during , and after radiation therapy . -
pubmed
METHODS : Seventy - three
women with
breast cancer completed questionnaires that assessed
sleep disturbance ,
depression ,
anxiety , and
pain prior to the initiation of RT and the Lee Fatigue Scale , over 6 months . -
pubmed
The relationship between chronic
volume overload and elevated blood pressure in hemodialysis
patients : use of bioimpedance provides a different perspective from echocardiography and biomarker methodologies . -
pubmed
BACKGROUND : Chronic
volume overload is very frequent in hemodialysis (
HD )
patients and is directly associated with
hypertension , increased arterial stiffness ,
left ventricular hypertrophy (
LVH ) ,
heart failure and ultimately with higher mortality and morbidity . -
pubmed
Forty - five percent of
patients ( group A ) had a reasonable control of BP and volume (
SBP & lt ; 150 mmHg and RTH & lt ; 15 % ) , 29.3 % ( group B ) were classified as
hypertensive (
SBP & gt ; 150 mmHg and RTH & lt ; 15 % ) , 16.7 % ( group C ) had
high blood pressure and marked volume expansion , (
SBP & gt ; 150 mmHg and RTH & gt ; 15 % ) , while 9 % ( group D ) had
SBP & lt ; 150 mmHg despite RTH & gt ; 15 % . -
pubmed
RESULTS : The analysis included 110
patients , 60 ( 55 % ) with grade one or greater
rash and 47 ( 43 % ) with grade one or greater
diarrhoea . -
pubmed
METHODS : Nine
Sprague - Dawley ( SD ) male rats were randomly divided into
SCI , normal and sham - operation control groups . -
pubmed
In this study , we report a novel 3 - Tesla RT -RI based
porcine RF ablation model and visualization of
lesion formation in the atrium during RF energy delivery . -
pubmed
In recent years , study of rare
bone diseases has led to the identification of signalling pathways that regulate bone formation and provided targets for the development of novel therapeutic agents to stimulate bone formation in
patients with
osteoporosis . -
pubmed
Blood pressure effects of
naproxcinod in
hypertensive patients . -
pubmed
The blood pressure ( BP ) effects of
naproxcinod and
naproxen were assessed in an 8 - week , double - blind , crossover study in 131
hypertensive patients aged 50 to 74 years . -
pubmed
Naproxcinod may be a beneficial alternative for
patients with
osteoarthritis requiring nonsteroidal anti - inflammatory drugs . -
pubmed
We report three cases of
bullous pemphigoid in
adults younger than 50 years old , discussing the clinical characteristics of the disease in younger
patients . -
pubmed
METHODS :
Patients included in the study were divided in two separate groups : 30
patients had
chronic wounds and 24
patients had superficial
traumatic wounds . -
pubmed
The lesion area and the rate of re - epithelialization were calculated , considering the time span and monitoring the
patients for clinical signs of
wound infection . -
pubmed
Patients satisfaction and compliance were evaluated by a questionnaire aimed at assessing
pain and ease of use of the device . -
pubmed
A single - arm pilot phase II study of
gefitinib and
irinotecan in
children with newly diagnosed high - risk
neuroblastoma . -
pubmed
Five
patients had partial responses ; 9 others had a 23%-60 % decrease in primary
tumor volume and/or improved MIBG scans or
decreased bone or bone marrow tumor burden . -
pubmed
Several papers reported about
patients with
cushingoid appearance , suggesting an
adrenal suppression related to
clobetasol systemic absorption after local application . -
pubmed
Traditional medicinal uses attributed to
Ardisia include alleviation of
liver cancer ,
swelling ,
rheumatism ,
earache ,
cough ,
fever ,
diarrhea ,
broken bones ,
dysmenorrhea ,
respiratory tract infections ,
traumatic injuries ,
inflammation ,
pain , snake and
insect bites ,
birth complications and to improve general blood circulation , among others . -
pubmed
Traumatic experiences that occur during adolescence can render
individuals vulnerable to mood and
anxiety disorders . -
pubmed
A
rat pain model of
facial cancer . -
pubmed
Although several
cancer pain animal models have been reported , these models have focused on the sciatic nerve areas . -
pubmed
To understand the mechanisms of
pain associated with
orofacial cancer , we recently created a
rat facial cancer model by inoculation of
cancer cells into the vibrissal pad . -
pubmed
This model provides mechanical
allodynia ,
thermal hyperalgesia , and
feeding disorder characteristics , similar to
orofacial cancer patients . -
pubmed
In this chapter , we describe in detail the generation of a facial
cancer pain model of
rats by inoculation of
Walker carcinosarcoma 256B cells . -
pubmed
TRUS - guided seminal vesicle aspiration can be used in conjunction with TRUS to confirm the diagnosis pre - operatively , especially in
patients with seminal vesicle dilation and a
prostatic midline / ejaculatory duct cyst on TRUS . -
pubmed
In
patients with findings of
chronic inflammation , such as
ejaculatory duct calcifications and
seminal vesicle atrophy/
hypoplasia on TRUS , proximal
vasal obstruction or functional
EDO should be excluded . -
pubmed
Outcomes of mechanical valves in the pulmonic position in
patients with
congenital heart disease over a 20 - year period . -
pubmed
BACKGROUND : Homografts or bioprosthetic valves have been preferred in the pulmonic position in
patients with
congenital heart disease . -
pubmed
The dried roots of
Euphorbia kansui ( kansui ) have been used for centuries in China as a herbal medicine for
edema ,
ascites , and
asthma . -
pubmed
Most
ingenane - type
diterpenoids and
8 - ene-7 - one triterpenoids ( 5 - 11 ) exhibited a relatively lower IC(50 ) value ; therefore , these compounds had stronger
cytotoxicity against
human normal cell lines
L - O2 and
GES-1 with dose - dependent relationships . -
pubmed
We report a case of a 68 - year - old female
patient who developed
hemophagocytic lymphohistiocytosis (
HLH ) secondary to
peripheral T - cell lymphoma (
PTCL ) not otherwise specified (
NOS ) that developed in the setting of treatment - resistant
B - cell small lymphocytic lymphoma /
chronic lymphocytic leukemia (
SLL /
CLL ) . -
pubmed
The
patient 's
B - cell lymphoma had a good initial response to chemotherapy for 4 years , after which it became less responsive and was thought to have undergone transition to a higher - grade
lymphoma . -
pubmed
Different regimens of chemoradiotherapy were then tried with modest response until the
patient presented 3 years later with
signs and symptoms of
HLH . -
pubmed
RESULTS : Four hundred seventeen
PD patients returned the questionnaire , with
RBD scores > = 6 in 172
patients . -
pubmed
These
patients had longer disease duration and lower activity of daily living scores , as well as more frequent
nighttime awakenings and
hallucinations than
PD patients with RBDSQ scores < 6 . -
pubmed
Herpes simplex encephalitis (
HSE ) is a rare but severe complication of frequent and mostly benign
infection with herpes simplex virus (
HSV ) . -
pubmed
Twenty - seven
patients ( 71.1 % ) were
neutropenic at the onset of
infection . -
pubmed
In immunocompromised hematology - oncology patients with severe
sepsis ,
S. - pubmed
This allows for future autotransplantation if a
patient becomes permanently
hypocalcemic after surgery . -
pubmed
Three of the 4
patients remained
hypoparathyroid after this procedure . -
pubmed
A Gram - reaction - negative , aerobic , motile by one polar flagellum , yellow - pigmented , rod - shaped bacterium , designated
strain THG - B117(T ) , was isolated from soil of a cornus fruit field of Hoengseong province in South Korea and its taxonomic position was investigated by a polyphasic study . -
pubmed
DNA - DNA hybridization experiments showed that DNA relatedness between
strain THG - B117(T ) and its phylogenetically closest neighbours was below 45.1 % . -
pubmed
The G+C content of the genomic DNA of
strain THG - B117(T ) was 64.8 mol% . -
pubmed
is proposed , with the type
strain THG - B117(T ) ( = KACC 16981(T ) = JCM 18747(T ) ) . -
pubmed
Prospective evaluation of intra - observer variability of the
hydronephrosis index in sonographic examination of 44
patients with
acute renal colic . -
pubmed
A historical perspective on the early treatment of
night blindness and the use of dubious and unproven treatment strategies for
patients with
retinitis pigmentosa . -
pubmed
The portal inflammatory infiltrate and ductular reaction in
human nonalcoholic fatty liver disease . -
pubmed
We present a case of
accessory scrotum associated with
lipomatous hamartoma in a 46 - year - old
man who was born with a
perineal mass . -
pubmed
A 29 - month - old
girl presented with
seizure and a brain magnetic resonance image revealed a huge heterogeneous mass in the left lateral ventricle . -
pubmed
Salmonella enterica serovar Typhi is associated with a disseminated
febrile illness in
humans , termed
typhoid fever , while
Salmonella enterica serovar Typhimurium causes
localized gastroenteritis in immunocompetent individuals . -
pubmed
Clinical application of transient elastography in
patients with chronic
viral hepatitis receiving antiviral treatment . -
pubmed
Accurate evaluation of the degree of
liver fibrosis in
patients with
chronic liver diseases (
CLD ) is crucial , as
liver fibrosis is important in determining the prognosis of
liver diseases . -
pubmed
In the past few years , the role of TE in monitoring liver stiffness and determining prognosis in
patients with
chronic hepatitis B (
CHB ) or
chronic hepatitis C (
CHC ) who are undergoing antiviral treatment has been investigated . -
pubmed
In
patients with
CHC , TE can be used to monitor potential regression of
liver fibrosis after antiviral treatment and may predict the treatment outcome of
CHC . -
pubmed
In addition , TE is an adjunct tool for distinguishing inactive
hepatitis B virus carriers from patients with
chronic active hepatitis . -
pubmed
METHODS : Data were from the Multi - Ethnic Study of
Atherosclerosis ( MESA ) , a population - based cohort study of 6749
adults , aged 45 to 84 years and free of clinical
cardiovascular disease at baseline , conducted at 6 US sites . -
pubmed
INTRODUCTION : There are little data about
patients with
cardiogenic shock (
CS ) who survive the early phase of
acute myocardial infarction (
AMI ) . -
pubmed
METHODS : We analyzed 5 - year follow - up data from the French registry of Acute ST - elevation and
non - ST - elevation Myocardial Infarction ( FAST - MI ) 2005 registry , a nationwide French survey including consecutive
patients admitted for
ST or non - ST - elevation
AMI at the end of 2005 in 223 institutions . -
pubmed
RESULTS : Of 3670
patients enrolled ,
shock occurred in 224 ( 6.1 % ) , and 3411 survived beyond 30 days or hospital discharge , including 99 ( 2.9 % ) with
shock . -
pubmed
CONCLUSIONS : In
patients surviving the early phase of
AMI ,
CS at the initial stage carries an increased risk of
death up to one year after the acute event . -
pubmed
Beyond one year , however , mortality is similar to that of
patients without
shock . -
pubmed
Fluoxetine - induced
tardive dyskinesia in a
patient with
Parkinson ' s disease . -
pubmed
We report two cases of elderly
patients who were diagnosed with
disc fracture of the TMJ based on MRI , and we review related reports . -
pubmed
On physical examination , an incomplete
bite and mild joint
pain were observed on the affected side in both
patients . -
pubmed
The first line of treatment for
individuals with
prediabetes is lifestyle modification , including diet and exercise . -
pubmed
The poor prognosis of
patients with
GBM underscores the clear and urgent need for more precise and potent therapies . -
pubmed
BACKGROUND :
Dengue viruses (
DENVs ) are mosquito - borne viruses which can cause disease ranging from mild
fever to severe
dengue infection . -
pubmed
Strains from at least two genotypes of
DENV-1 ( Asia and America / Africa genotypes ) have been circulating in western Saudi Arabia until 2006 . -
pubmed
FINDINGS : Here , we report the isolation and the first complete genome sequence of a
DENV-1 strain (
DENV-1 - Jeddah-1 - 2011 ) isolated from a patient from Jeddah , Saudi Arabia in 2011 . -
pubmed
Whole genome sequence alignment and phylogenetic analysis showed high similarity between DENV-1 - Jeddah-1 - 2011
strain and
D1 / H / IMTSSA / 98 / 606 isolate ( Asian genotype ) reported from Djibouti in 1998 . -
pubmed
Our aim was to evaluate the results of combining endovascular treatment of SFA with distal vein bypass in
patients with
critical limb ischemia (
CLI ) and great tissue loss or in the cases where the below - knee endoluminal techniques alone were unable to salvage limbs . -
pubmed
CONCLUSION : The endovascular treatment of SFA associated with surgical distal vein bypass is a useful and effective strategy in
patients with severe
lower extremity arterial disease . -
pubmed
This paper reviews the nonotogenic causes of persisting
dizziness , the possible mechanisms , and the pathophysiology , as a framework for
patient management and for future research . -
pubmed
The experiment was performed on 30 female Polish
Large White pigs , aged 2 months , with
body weight of 15 - 18 kg , divided into two groups : control ( C , n = 15 ) and experimental ( Z , n = 15 ) . -
pubmed
Antiretroviral Effects on Host Lipoproteins Are Associated With Changes in Hepatitis C Virus (
HCV ) RNA Levels in
Human Immunodeficiency Virus / HCV Coinfected Individuals . -
pubmed
We evaluated the impact of antiretroviral - induced
dyslipidemia on
hepatitis C virus (
HCV ) biogenesis in
human immunodeficiency virus ( HIV )/ HCV coinfected patients . -
pubmed
This study used serum samples from antiretroviral - naive
HIV /
HCV patients initiating their first regimen as part of
AIDS Clinical Trials Group study protocols ( A5142 , A5202 ) . -
pubmed
Off - target lipogenic changes need to be considered in the context of liver and other
metabolic disease in
HIV /
HCV patients . -
pubmed
Short communication : use of the BetaStar Plus assay for detection of
ceftiofur antimicrobial residues in milk from individual
cows following intramammary treatment for
mastitis . -
pubmed
The objective of this study was to evaluate the effectiveness of a lateral - flow immunodiagnostic assay ( BetaStar Plus , Neogen Corp. , Lansing , MI ) in detecting
ceftiofur residues in milk from individual
cows treated for
mastitis . -
pubmed
Forty - five dairy
cows with clinical
mastitis from 4 dairy farms were enrolled and treated intramammary with 125 mg of
ceftiofur hydrochloride ( Spectramast LC , Zoetis , Madison , NJ ) according to the manufacturer 's label recommendation . -
pubmed
The BetaStar Plus assay could be useful for detecting
ceftiofur residues in milk from individual
cows following intramammary treatment for
mastitis before the milk is shipped for processing . -
pubmed
In this study , we isolated primary pancreatic fibroblasts from wild type
C57 mice and co - cultured them with
pancreatic cancer cell lines ,
BxPC-3 and
SW1990 , and observed the conversion from NF to CAF , or at least CAF - like cells . -
pubmed
FG-4592 administration also improved recovery and increased the survival of neurons in
spinal cord lesions in the
mice model . -
pubmed
While the introduction of anti - tVEGF agents has significantly improved visual outcomes of
patients with
DR , unpredictable response , largely due to genetic polymorphisms , appears to be a challenge with this therapy . -
pubmed
With advances in identification of various genetic biomarkers , novel therapeutic strategies consisting of gene transfer are being developed and tested for
patients with
DR . -
pubmed
Oral
steroids for the resolution of
otitis media with
effusion (
OME ) in
children ( OSTRICH ): study protocol for a randomised controlled trial . -
pubmed
BACKGROUND :
Otitis media with effusion (
OME ) is an accumulation of fluid in the middle ear affecting about 80 % of
children by the age of 4 years . -
pubmed
Children with persistent
hearing loss associated with
OME are usually offered hearing aids or insertion of ventilation tubes through the tympanic membrane . -
pubmed
The aim of the Oral
Steroids for the Resolution of
Otitis Media with
Effusion in
Children ( OSTRICH ) trial is to determine if a short course of oral
steroids improves the hearing of
children with
OME in the short and longer term . -
pubmed
A trained clinician seeks informed consent from parents of
children with symptoms for at least 3 months that are attributable to
OME and with confirmed bilateral
hearing loss at study entry . -
pubmed
Drugs for preventing red blood cell
dehydration in
people with
sickle cell disease . -
pubmed
AUTHORS ' CONCLUSIONS : While the results of
zinc for reducing sickle - related crises are encouraging , larger and longer - term multicenter studies are needed to evaluate the effectiveness of this therapy for
people with
sickle cell disease . -
pubmed
MATERIAL AND METHODS : The files of 38
patients , with recurrent
laryngeal nerve injury following thyroidectomy , that were referred to Istanbul Forensic Medicine Institute with request of expert opinion between 2008 - 2012 were retrospectively investigated . -
pubmed
Nineteen
patients had unilateral , and 19
patients had bilateral
nerve damage . -
pubmed
PURPOSE :
Dyslexia is one of the most common
learning disabilities affecting millions of
people worldwide . -
pubmed
Thirteen
children with
dyslexia and 13 sex- and age- matched controls performed three psychophysical tasks . -
pubmed
CONCLUSION : We may suggest that
dyslexic subjects might suffer from both magnocellular and parvocellular deficits . -
pubmed
MATERIALS AND METHODS : Hero 's modified Di Chiro classification differentiated four types of
spinal AVMs on digital subtraction angiogram ( DSA ) in 74
patients : I. -
pubmed
A
patient with extradural
AVM remained unclassified . -
pubmed
The present study reports the case of a male
patient presenting with multiple bilateral
cortical kidney cysts at the age of 4 years , at which time the kidneys were of normal size and function . -
pubmed
Most brands of soy milk tested in our study had
fluoride content below the optimal daily intake but brands containing
tea powder extract if consumed by children may increase their risk for
fluorosis . -
pubmed
Guar gum as a new antimicrobial peptide delivery system against
diabetic foot ulcers Staphylococcus aureus isolates . -
pubmed
Diabetic patients frequently develop
diabetic foot ulcers (
DFUs ) , particularly those patients vulnerable to
Staphylococcus aureus opportunistic infections . -
pubmed
Both were
patients with
inflammatory bowel disease [
IBD ] , treated successfully with
adalimumab . -
pubmed
Vigilance is appropriate when
patients present with symptoms compatible with
sarcoidosis . -
pubmed
Temporomandibular disorders and quality of life among 12 - year - old
schoolchildren . -
pubmed
Although its blockade has effective anticancer effects in experimental models , it may lead to fatal
arrhythmias in
humans . -
pubmed
Extensive
Usutu virus activity in the Netherlands in 2016 underlines the need to monitor mosquito activity and
mosquito - borne infections in 2017 and beyond . -
pubmed
High -
sucrose - induced maternal
obesity disrupts ovarian function and decreases fertility in
Drosophila melanogaster . -
pubmed
Using our previously reported
Drosophila high -
sucrose maternal
obesity model , we sought to determine how excess dietary
sucrose impacted the ovary . -
pubmed
PURPOSE : The purpose of this study was to evaluate the clinical features and the long - term outcomes of primary
conjunctival marginal zone B - cell lymphoma (
MZBCL )
patients who were treated with radiation therapy ( RT ) . -
pubmed
MATERIALS AND METHODS : Retrospective data of 79
patients with 121 primary
conjunctival MZBCL lesions were collected from January 1 , 2001 till June 30 , 2014 . -
pubmed
CONCLUSION : 26 Gy 's RT was highly effective and safe , with the use of lens - shielding device , in treating
patients with primary
conjunctival MZBCL . -
pubmed
For
women age & lt;45 years allocated 5 years of
tamoxifen , the risk of contralateral
breast cancer is halved over 15 years . -
pubmed
Premenopausal
women with
ER + ve HER2 - negative breast cancer with high - risk features can derive a meaningful improvement in 5 - year invasive
breast cancer - free interval with
exemestane plus
ovarian suppression , as an alternative to
tamoxifen . -
pubmed
Phosphoproteomic Analysis Identifies Signaling Pathways Regulated by
Curcumin in
Human Colon Cancer Cells . -
pubmed
Quantitative comparison of the spreading and invasion of radial growth phase and
metastatic melanoma cells in a three - dimensional
human skin equivalent model . -
pubmed
RESULTS : Twenty
patients who later developed
DCI were included , and twenty - eight
patients without
DCI were identified for comparison . -
pubmed
XeCT may be potentially helpful in managing poor - grade
SAH patients . -
pubmed
Hepatoprotective effect of
calculus bovis sativus on
nonalcoholic fatty liver disease in
mice by inhibiting oxidative stress and apoptosis of hepatocytes . -
pubmed
In Asian countries ,
CB Sativus ( CBS ) , an ideal substitute for natural CB , is presently extensively used for long - term treatment of chronic
liver diseases . -
pubmed
The
NAFLD model was established in C57BL/6
mice by exclusively feeding fluids containing 30 %
fructose for 8 consecutive weeks . -
pubmed
Histopathological examination showed that
liver steatosis and
injury were significantly reduced in
CBS - treated
mice . -
pubmed
In conclusion ,
CBS treatment exerted therapeutic effects in the liver of
mice with
NAFLD , which may be associated with amelioration of
metabolic disorders , enhanced antioxidant effects , and alleviation of apoptosis . -
pubmed
We herein present the case of a 23 - year - old
man with poorly controlled
T1DM who had
liver dysfunction . -
pubmed
In this case , the improvement of
hyperglycemia , not HbA1c , resulted in the improvement of the
patient 's liver function . -
pubmed
DESIGN : Observational cohort study of
subarachnoid hemorrhage patients ( n = 133 ) admitted to rehabilitation ( n = 49 ) , discharged home ( n = 52 ) , or died before discharge ( n = 10 ) . -
pubmed
Since the introduction of direct - acting antivirals ( DAAs ) , the outcomes of
hepatitis C (
HCV ) treatment have shown an improvement in cure rates with minimal side effects . -
pubmed
Species differences in renal drug transporters continue to plague drug development with animal models failing to adequately predict
renal drug toxicity . -
pubmed
For example ,
adefovir , a renally excreted antiviral drug , failed clinical studies for
human immunodeficiency virus due to pronounced
nephrotoxicity in
humans . -
pubmed
Developmental coordination disorder (
DCD ) is a
neurodevelopmental disorder affecting 5 - 6 % of
children that is characterized by deficits in motor skills . -
pubmed
Studies show that
children with
DCD have motor timing and sensorimotor timing deficits . -
pubmed
This idea is consistent with evidence from several domains , ( 1 ) motor - related brain regions are often involved in auditory timing process ; ( 2 )
DCD has high comorbidity with
dyslexia and
attention deficit hyperactivity , which are known to be associated with auditory timing deficits ; ( 3 ) a few studies report deficits in auditory - motor timing among
children with
DCD ; and ( 4 ) our preliminary behavioral and neuroimaging results show that
children with
DCD at age 6 and 7 have
deficits in auditory time discrimination compared to typically developing
children . -
pubmed
PURPOSE : The aim of this pilot study was to evaluate the effect of a multicomponent balance and resistance training intervention on physical function , balance , and falls in older ( & gt;=65 years ) community - dwelling
heart failure (
HF )
patients . -
pubmed
CONCLUSIONS : A supervised group session intervention can increase mobility and gait and reduce fall rate for
HF patients . -
pubmed
CLINICAL RELEVANCE : This study was designed to improve lower extremity strength , balance , and falls in elderly
HF patients , thus reducing costs and improving quality of life for this population . -
pubmed
MATERIAL AND METHODS : 76 cases of
ameloblastoma were investigated , the average age of the
patients was 46 years . -
pubmed
PURPOSE : To evaluate the outcome of surgical treatment in
patients with
type 1 monocular elevation deficiency . -
pubmed
METHODS :
Patients who were diagnosed as having
type 1 monocular elevation deficiency by forced duction test and exaggerated traction test between 2000 and 2016 were retrospectively reviewed . -
pubmed
The clinical features of the
patients who did not achieve surgical success after
inferior rectus recession were determined . -
pubmed
The surgical and functional results of contralateral
superior rectus recession were evaluated for
patients who had residual
hypotropia under
inferior rectus recession . -
pubmed
Ten ( 25.64 % )
patients did not achieve surgical success ( & gt ; 6 PD residual
hypotropia ) . -
pubmed
CONCLUSIONS :
Inferior rectus recession is the first surgical option for
patients with
type 1 monocular elevation deficiency . -
pubmed
Patients undergoing cytotoxic or immunosuppressive therapy for
cancer have an established predilection for
hepatitis B virus reactivation ; however , the risk associated with newer molecularly targeted agents has not been well investigated . -
pubmed
We report the case of a
patient who developed
hepatitis B virus reactivation while receiving
imatinib therapy for
gastrointestinal stromal tumor . -
pubmed
Imatinib - associated
hepatitis B virus reactivation was reported in seven patients with
chronic myeloid leukemia , one with
desmoid tumor , and one with
gastrointestinal stromal tumor . -
pubmed
We aim to increase awareness about this possible association and advocate for
hepatitis B virus screening prior to
imatinib therapy , especially in patients who are at increased risk for
chronic hepatitis B virus infection . -
pubmed
We queried prehospital databases to identify cases , which included all adult
patients ( & gt;= 18 years ) with a prehospital
glucose reading of & lt;72mg / dl ( 4.0mmol / L ) and excluded terminally ill and
cardiac arrest patients . -
pubmed
Successful recovery of associated
interstitial nephritis and
focal segmental glomerulosclerosis in
patients with
HCV and
HIV treated with
sofosbuvir and
daclatasvir and revision of literature . -
pubmed
In this report , we describe the coexistence of two rare and debated complications of
hepatitis C virus ( HCV ) infection :
interstitial nephritis , with associated
focal glomerulosclerosis , and
autoimmune hepatitis , in a 55 - year - old HIV /
HCV - coinfected woman . -
pubmed
A 24 - year - old
patient with
anaplastic astrocytoma requiring chemotherapy with
temozolomide for 12 cycles as soon as possible with wish for fertility preservation while using a long acting
etonogestrel birth control implant presented in our unit for fertility preservation in May 2017 . -
pubmed
IVM could be a possibility for fertility preservation in
patients with
polycystic ovaries when no time is available for stimulation for conventional in vitro fertilization . -
pubmed
Method : We recruited 22
patients under 15 years of age with
cough lasting longer than 4 weeks ( group 1 ) , 7 controls with
allergic rhinitis ( group 2 ) , and 10 controls without
respiratory symptoms ( group 3 ) . -
pubmed
Results : Group 1A (
cough with clinical bacterial
sinusitis n = 10 ): Eight ( 80 % ) patients had
bacterial sinusitis associated with dominant potential pathogenic bacteria ( PPB ):
Streptococcus pneumoniae ,
Haemophilus influenzae , and
Moraxella catarrhalis . -
pubmed
Delayed febrile response with
bloodstream infections in
patients with continuous - flow left ventricular assist devices . -
pubmed
We observed 59
BSIs in LVAD
patients and 45
BSIs in controls . -
pubmed
Group I
patients showed better improvement in terms of
functional impairment ( Inability Walking Scale ) , reported
pain ( visual analogue scale ) , and daily intake of
etoricoxib 60 mg . -
pubmed
We also investigated the impact of serum collected from HFD / CD pregnant
rats on
CD embryonic development in whole - embryo cultures . -
pubmed
These findings suggest that
metabolic disturbances in
HFD pregnant
rats have profound adverse developmental effects in the offspring . -
pubmed
To investigate the use of a corneal impression membrane ( CIM ) for the detection of
herpes simplex virus type 1 (
HSV-1 ) in suspected
herpes simplex keratitis (
HSK).Methodology . -
pubmed
In suspected
HSK , a
CIM is a useful alternative to a swab and more likely to detect the presence of
HSV-1 . -
pubmed
We aimed to investigate the effects of
DAA - therapy on
liver inflammation ,
fibrosis , metabolic function and cognitive function and the time course in
CHC patients with advanced
liver disease . -
pubmed
Seventy - one
CHC patients with advanced
liver disease were studied before , during , and one year after successful
sofosbuvir - based DAA - therapy . -
pubmed
SUBJECTS / METHODS : This cross - sectional study involved 95 ( 45 had MA and 50 had no MA )
patients with
type 2 diabetes mellitus (
DM ) without
DR and 91 age- and gender - matched non - diabetic controls . -
pubmed
However ,
diabetic patients ( n = 95 ) had significantly thinner inferior - temporal peripapillary retinal nerve fibre layer ( RNFL ) ( p = 0.042 ) than in the controls ( n = 91 ) . -
pubmed
However , 3 mm - nasal , temporal and superior perifoveal thicknesses were significantly lower in
patients with
DM duration over 10 years ( p & lt ; 0.05 ) . -
pubmed
CONCLUSIONS : In diabetic
patients without
DR , peripapillary inferior - temporal RNFL thinning might be an early sign of
neuroretinal degeneration and it seems to be independent from
vascular endothelial damage (
MA ) . -
pubmed
METHODS : In a 2017 cross - sectional study of rectal
STI screening and
HIV prevention , a convenience sample of MSM recruited from community venues in Lima completed a survey of demographic characteristics and sexual risk behavior with their three most recent partners . -
pubmed
Etiology for
airway stenosis in all
patients of study group was intubation
injury . -
pubmed
METHODS : A randomized controlled trial targeting Hiroshima University
students was performed to assess the
plaque removal efficacy of
polybutylene terephthalate (
PBT ) manual toothbrushes . -
pubmed
Predictive factors for progression - free survival in
non - small cell lung cancer patients receiving
nivolumab based on performance status . -
pubmed
METHODS : We retrospectively collected pretreatment clinical data of 296 consecutive
patients with
NSCLC treated with
nivolumab . -
pubmed
Internet society ,
internet addiction , and pathological social withdrawal : the
chicken and egg dilemma for
internet addiction and hikikomori . -
pubmed
METHODS : The study included in 59 non - smoker
asthma patient ( Exacerbated=25 , Stable=34 ) and 30 healthy
volunteers . -
pubmed
Patients with > =3 risk factors had more severe
pain intensity scores , spent a longer time in severe
pain , and wished to have received more
pain treatment ( P < 0.001 ) . -
pubmed
Conclusions :
Patients with > =3 risk factors are at higher risk for poor postoperative acute
pain outcome after surgery . -
pubmed
The effects of manual manipulation therapy on
pain and dysfunction in
patients with
lumbar spinal stenosis . -
pubmed
[ Purpose ] This study investigated the effects of manual manipulation therapy on the
pain and dysfunction of
patients with
lumbar spinal stenosis . -
pubmed
[ Participants and Methods ] In this study , 30
patients with
chronic back pain were evenly divided into an experimental group , who received manual traction therapy , and a control group , who received intermittent traction therapy . -
pubmed
[ Conclusion ] The results of this study suggest that manual manipulation therapy is an effective intervention for treating
pain and dysfunction in
patients with
lumbar spinal stenosis . -
pubmed
The
patient underwent an initial fine - needle aspiration biopsy ( FNAB ) of an enlarged cervical lymph node followed by surgical excision of the
tumor and immunohistochemistry which confirmed the diagnosis . -
pubmed
CRAFT - RCT : Randomised controlled trial arm ; To assess treatment for short cervix in
women at high risk of
preterm birth following a fully dilated caesarean section . -
pubmed
Studies on
human gingival fibroblasts in vitro revealed that the obtained microparticles did not induce any
cytotoxic effects . -
pubmed
Clinically , the combination of these two therapies has been used as a treatment for
tendon and ligament lesions in
horses ; however , there is no scientific evidence supporting this combination of therapies in vivo . -
pubmed
Human sparganosis in Arkansas . -
pubmed
Long - term ( 48 - hr ) incubations of either the fibroblast
strain WI-38 or its
SV40 - transformed counterpart ,
WI-38 - VA13 - 2RA , in growth medium containing 1 micron
prostaglandin E1 (
PGE1 ) resulted in a sustained production and release of
cyclic AMP from the cells into the medium . -
pubmed
Enrichment culture of organisms growing anaerobically in the light in
methanol -
bicarbonate medium resulted in isolation of
strains of
Rhodopseudomonas gelatinosa and
Rhodopseudomonas acidophila . -
pubmed
[ Controlled
hypotension with
sodium nitroprosside in
patients placed in the sitting position during intracranial operations ( author 's transl ) ] . -
pubmed
Sodium nitroprusside was used to induce
hypotension during continuous neuroleptanalgesia in 11 neurosurgical
patients aged between 13 and 53 years placed in the sitting position . -
pubmed
No
patient had
cardiovascular disease . -
pubmed
14
patients aged between 18 and 72 years without induced
hypotension were used as controls to compare the action of our standardized method of anaesthesia on the same parameters that were also monitored during blood pressure lowering . -
pubmed
Cerebral perfusion of these 14
patients with highly elevated intracranial pressure with or without
cardiovascular disease already seemed to be threatened by the upright position . -
pubmed
Careful monitoring of the
patients during and after blood pressure lowering with
sodium nitroprusside made it possible to take advantage of the induced
hypotension also in strictly - selected neurosurgical
patients who have to be operated on in upright position . -
pubmed
The postoperative
patient is at high risk , as is the
patient with
cancer or
renal failure . -
pubmed
Abnormal
bleeding was common , but significant
hemorrhage occurred only in postoperative
patients . -
pubmed
Action of
phenytoin ,
ethosuximide and of the
carbidopa -
L - dopa association in semi - chronic
cobalt - induced
epilepsy in the
rat . -
pubmed
A semi - chronic model of
cobalt - induced experimental
epilepsy in the
rat was used to investigate the action of two classic anticonvulsant drugs ,
phenytoin and
ethosuximide . -
pubmed
Malignant melanoma has provided an excellent model system for studying crucial events in
human tumor development and progression . -
pubmed
[ Changes in the intracranial pressure in relation to body posture and their use in the treatment of
patients after
cranio - cerebral injuries ] . -
pubmed
The determination of the best body position in
patients after
cranio - cerebral injuries was the main subject of the undertaken studies . -
pubmed
The positional changes of the intracranial pressure and cerebral perfusion pressure as well as cerebral elasticity were analyzed in 11
patients after
cranio - cerebral injuries . -
pubmed
The retrospective studies in 157
patients after
cranio - cerebral injuries permitted me to compare the results of the classical treatment and the positioning one . -
pubmed
The WO-1
strain of
Candida albicans is capable of alternating between two highly distinct
yeast cell types termed white and opaque ( E. H. A. Rikkerrink , B. -
pubmed
Pre- and postoperative evaluation of renal function with five different tests in
patients with
primary hyperparathyroidism . -
pubmed
Renal function was investigated immediately before and 1 year following parathyroidectomy in 19
patients with moderate
hypercalcaemia . -
pubmed
Glomerular filtration rate , as assessed by plasma
creatinine and clearance of both
creatinine and
51Cr - EDTA , was normal in most
patients , and was little affected by restoration of
normocalcaemia . -
pubmed
It is concluded that serious
renal damage is seldom encountered in present - day
HPT patients , but that a treatable decrease in renal concentrating capacity often exists . -
pubmed
The purpose of this study was to evaluate the association between anti - phospholipid antibodies and
cardiac abnormalities in
patients with
SLE . -
pubmed
PATIENTS AND METHODS : A total of 75 consecutive
SLE patients and 60 healthy sex- and age - matched control subjects were evaluated in a case - control study . -
pubmed
In 36
patients with mild , moderate and severe
aortic stenosis , proved by cardiac catheterization , some electrocardiographic indices for
left ventricular hypertrophy were compared with the value of the aortic valve peak systolic gradient . -
pubmed
The nocturnal secretion of plasma
melatonin was determined under dim to dark conditions in eight
patients with prospectively confirmed
premenstrual syndrome and in eight age- and menstrual cycle phase - matched normal control subjects . -
pubmed
Compared with normal controls ,
patients with
premenstrual syndrome had an earlier ( phase - advanced ) offset of
melatonin secretion , which contributed to a shorter secretion duration and a decreased area under the curve . -
pubmed
The fact that these
patients respond to treatments that affect circadian physiology , such as
sleep deprivation and phototherapy , suggests that
circadian abnormalities may contribute to the pathogenesis of
premenstrual syndrome . -
pubmed
Flow patterns and spatial distribution of
atherosclerotic lesions in
human coronary arteries . -
pubmed
To investigate the potential role of fluid mechanical factors in the localized genesis and development of
atherosclerotic lesions in
humans , the exact anatomic locations of
atherosclerotic lesions and the flow patterns at such sites in left and right
human coronary arteries were studied in detail by flow visualization and high - speed cinemicrographic techniques using five isolated , transparent
human coronary arterial trees prepared postmortem . -
pubmed
The results indicate that the major hemodynamic factors directly related to the localization of
atherosclerotic plaques and wall thickenings in the
human arterial system are the low fluid velocity and the resultant low shear stress that acts on the vessel wall . -
pubmed
There was no significant difference in the
pulse frequencies between the
patients and controls but the amplitude of both groups of
pulses was increased in the
PCOS patients . -
pubmed
This finding indicates that at least two different
genetic defects participate in the formation of the high incidence of spontaneous SCEs in
mouse cells . -
pubmed
As
burn therapy has enabled increasing numbers of
patients to survive extensive
burns , it is imperative that preservation of function not be ignored and that attention be directed at improved function early in the postburn course . -
pubmed
The in situ degradation of rapidly transported proteins in nerve terminals of retinal
ganglion cells was studied in pieces of the superior colliculus of the
rabbit . -
pubmed
[ Leukocyte migration inhibition response in
patients with
osteoarthrosis deformans ] . -
pubmed
[ Ultrastructural study on the effect of
pyronaridine on the erythrocytic stages of
chloroquine - resistant
strain of
Plasmodium berghei ] . -
pubmed
Emotional alterations of these
animals may account for this result , whereas true
cognitive deficits are likely to underly the
impairment of learning set formation seen in the low lead group . -
pubmed
This technique is particularly applicable to elderly , poor risk
patients and those
patients with villous
adenomas which extend so low in the rectum that anterior resection would be difficult or impossible . -
pubmed
[ Further investigation to the immunology of
murine mammary tumours of the CBA - Bln
strain using the colony inhibition tests ( author 's transl ) ] . -
pubmed
Language and the education of
children with early profound
deafness . -
pubmed
Evidence for selection of homogeneously staining regions in a
human melanoma cell line . -
pubmed
Cytogenetic analysis of
tumor cells from a
human malignant melanoma was performed on both the primary
tumor colony - forming cells and a cell line (
HA - A ) established subsequently from the clonogenic population . -
pubmed
This represents the first observation of
DMs or HSRs in cells from a
human malignant melanoma . -
pubmed
[ Effects of
10 - hydroxycamptothecin on
cAMP and
cGMP levels in
hepatoma and liver tissue of
mice ( author 's transl ) ] . -
pubmed
Fever ,
cough ,
anal ulcer in a heterosexual
man . -
pubmed
Prognostic significance of parametrial extension in
patients with
cervical carcinoma Stages IB , IIA , and IIB . -
pubmed
Parametrial extension was evaluated as a prognostic factor in 628
patients with
cervical carcinoma treated by radical hysterectomy and pelvic lymphadenectomy at the Aichi Cancer Center in Nagoya , Japan . -
pubmed
Vaterite gallstones in a
canary (
Serinus canarius ) . -
pubmed
[ The effect of short - term lung inflation on the strength of the expiratory reflex in
ferrets under normal conditions and in experimental
pneumothorax ] . -
pubmed
Two hundred and ninety - eight
patients attending their general practitioner and requiring treatment for
respiratory tract infections were randomly allocated to receive either 250 mg
cefaclor 3 - times daily ( intermittent ) or 500 mg
amoxycillin 3 - times daily ( continuous ) . -
pubmed
A combination therapy consisting of two endolymphic infusions of BCG vaccine and
methotrexate followed by remote gamma therapy 10 days after the second infusion was given to 96
patients with
stage III esophageal tumors . -
pubmed
Kinetic constants of asialoorosomucoid endocytosis comparison between hepatocytes from normal and
streptozotocin -
diabetic rats . -
pubmed
The findings lend support to our hypothesis and observation that the
human breast secretes mutagenic and
cancer - promoting substances which may have relevance in studies of the etiology of
benign breast disease and
cancer . -
pubmed
Report of a case and review of the literature .. A 13 - year - old
boy had
obstructive jaundice following several episodes of blunt
abdominal trauma . -
pubmed
Immediate versus delayed fluid resuscitation in
patients with
trauma . -
pubmed
We describe a 23 - year - old
woman without
coronary artery disease who had an acute non - Q - wave
myocardial infarction and
stunned myocardium after receiving topical
phenylephrine hydrochloride and
cocaine anesthesia for elective nasal septoplasty . -
pubmed
Time- and frequency - domain analyses of the signal - averaged ECG in
patients with
arrhythmogenic right ventricular dysplasia . -
pubmed
This study evaluated the usefulness of the frequency - domain analysis of the SAECG in addition to the conventional time - domain analysis for a screening test to detect
patients with
ARVD . -
pubmed
METHODS AND RESULTS : SAECG was recorded by using a bipolar X , Y , and Z lead system in 28
patients with
ARVD ( mean age , 38 + /- 13 years ) and 35 age - matched normal
subjects ( mean age , 35 + /- 11 years ) . -
pubmed
The authors report the occurrence of primary eosinophilic
granuloma of the oculomotor nerve without osseous involvement in a 68 - year - old
man . -
pubmed
A series of 12
patients with tectal plate
gliomas , is presented treated by direct surgery . -
pubmed
AIM : The purpose of the present study was to know the incidence and risk factors associated with
amikacin nephrotoxicity in a cohort of
patients form a general medial center . -
pubmed
Patients with other risk factors to develop
acute renal failure were excluded . -
pubmed
RESULTS : Ten
patients developed
nephrotoxicity ( 9.6 % ) . -
pubmed
Two groups of
patients were studied : group with stable
coronary artery disease and group without the
coronary artery disease as well as glycaemia and
insulinaemia were studied during the oral
glucose tolerance test . -
pubmed
A
patient with
lumbar lipomyelomeningocele with tethered cord ,
lower thoracic syringomyelia and
Chiari I malformation , shown by MRI is reported . -
pubmed
Nineteen
patients with symptomatic
anastomotic leakage after anterior resection were compared with 19 without leakage . -
pubmed
The study was carried out for reviewing the hypothesis on the relationship between integrated fish farming ( IFF ) and
human influenza A pandemic using study methods of longitudinal epidemiology , ecology and serology . -
pubmed
Four rural villages with IFF , non - IFF and non - fish farming , selected from two provinces ( Henan and Shandong of PRC ) were investigated for the status about
human influenza A epidemic and
infections with
human , duck ,
swine influenaz A viruses in those communities . -
pubmed
The results put forward views on that there is no relation between IFF and the increase of incidence rate ,
infection rate and antibodies level to
human influenza A virus . -
pubmed
Duck may play an important role in the increase of
infection rate to
human influenza A viruses among
human communities . -
pubmed
Pigs seem not to play obvious role in the increase of
infection rate to
human influenza A viruses among
human communities . -
pubmed
The ratio of sites with
gingivitis to sites with
bacterial plaque was calculated ( G / P - ratio ) . -
pubmed
OBJECTIVE : To evaluate whether
pulmonary embolism (
PE ) , as detected by perfusion lung scan , could be predicted by the ultrasonic ( US ) characteristics of the
thrombi in
patients with
deep venous thrombosis (
DVT ) of the lower limbs . -
pubmed
PATIENTS : Ninety - three consecutive
patients with
DVT and no symptoms of lung involvement ( 52
men , 41
women ; mean age , 67 + /- 17 years ) . -
pubmed
The diagnosis of
PE ( PIOPED criteria ) was highly probable in 46 % of the
patients , intermediate in 15 % , low in 8 % , and very low / normal in 31 % . -
pubmed
Low - dose
pulse methotrexate has emerged as one of the most frequently used slow - acting , symptom - modifying antirheumatic drugs in
patients with
rheumatoid arthritis (
RA ) because of its favourable risk - benefit profile . -
pubmed
Furthermore , studies in
patients with
juvenile rheumatoid arthritis provide evidence of age - dependent pharmacokinetics of the drug . -
pubmed
Finally , both
trimethoprim - sulfamethoxazole (
cotrimoxazole ) and
probenecid lead to increased
toxicity of
methotrexate , and hence should be avoided in
patients receiving these drugs . -
pubmed
Aortocaval fistulae : a percutaneous model and treatment with stent grafts in
sheep . -
pubmed
ACFs were successfully created in all
animals , with rapid dye shunt through the
fistula and a 20 % increase in cardiac pulsations . -
pubmed
The method was applied to samples from
patients with
deficiency in tryptophan metabolism ,
xanthurenic acid/
3 - hydroxy kynurenineuria and showed a striking elevation in serum
8 - methyl ether of
xanthurenic acid . -
pubmed
There were 9 adverse events ( reaction rate of 8.3 % ) in 6
patients with 5 %
NSA and 12 events ( reaction rate 12.1 % ) in 8
patients with
Albumex 5 . -
pubmed
Apoptosis and proliferation of fibroblasts during postnatal skin development and
scleroderma in the tight - skin
mouse . -
pubmed
Tight - skin ( Tsk ) is a dominant gene mutation that causes a
fibrotic skin disease in
mice , similar to
human scleroderma . -
pubmed
Eighteen
patients with primary mediastinal
germ cell tumour were treated over an 1 - year period ; 9 had
seminoma and 9
non - seminoma . -
pubmed
All
patients with
seminoma received consolidation radiotherapy to mediastinum . -
pubmed
Three
patients with
non - seminoma received radiotherapy following partial response . -
pubmed
All 9
patients with
seminoma achieved complete response at the end of chemotherapy . -
pubmed
Two
patients who underwent resection of the residual
tumour mass are surviving free of disease . -
pubmed
Nine out of 9
patients with
seminoma and 4/9 with
non - seminoma are surviving disease - free at a median follow - up of 48 months ( range 16 153 months ) . -
pubmed
Effect of
sucralfate on
aspirin induced
mucosal injury and impaired haemostasis in
humans . -
pubmed
Twenty - four hour blood pressure profile of different doses of
candesartan cilexetil in
patients with mild to moderate
hypertension . -
pubmed
Visual assessment of
human skin irritation : a sensitive and reproducible tool . -
pubmed
Human volunteer studies of
skin irritation have been carried out for decades , both for research and for safety evaluation purposes . -
pubmed
However , it is possible to use the
human eye , which is a very sensitive tool , to make detailed , accurate and reproducible descriptions of
skin irritation reactions . -
pubmed
CASE REPORT : An 86 - year - old
woman , with a 16 - month history of an
external auditory canal mass , presented with
hemiparesis , facial
paralysis , and obtundation . -
pubmed
METHOD : The
patient had a craniotomy for intracranial
tumor resection with concurrent mastoidectomy for facial nerve decompression and obtundation and
hemiparesis were resolved . -
pubmed
Omeprazole or
ranitidine plus
metoclopramide for
patients with severe
erosive oesophagitis . -
pubmed
In conclusion , superior efficacy at comparable cost is achieved by
omeprazole compared with
ranitidine /
metoclopramide in the treatment of
patients with severe
erosive oesophagitis . -
pubmed
About half ( 54 % ) of 106
patients with
structural heart disease had surgically induced
heart block . -
pubmed
Patients with
sick sinus syndrome had similar outcomes to those with
AV block . -
pubmed
The overall survival of young
patients without
structural heart disease who received a permanent pacemaker was comparable to an age- and sex - matched control population , while patients with
structural heart disease performed significantly worse than the control population . -
pubmed
This study examined 3 - dimensional ( 3D ) distribution of sectors with contrasting density in the
equine third metacarpal ( McIII ) and third metatarsal ( MtIII ) bones with a view to explaining the aetiology of distal
condylar fractures . -
pubmed
[
Nitric oxide levels in cephalorhachidian++ fluid in
patients with
HIV infection ] . -
pubmed
Three - dimensional spheroid cultures of
human prostate cancer cell lines . -
pubmed
BACKGROUND : Many of the available
human prostate cancer ( PC ) cell lines have lost
androgen sensitivity and no longer secrete prostate - specific proteins after serial culturing in cell monolayers . -
pubmed
Detection of acute
myocardial infarction by
99mTc - labeled D - glucaric acid imaging in
patients with acute
chest pain . -
pubmed
To determine whether imaging with
99mTc - labeled D - glucaric acid (
GLA ) could provide this information , we imaged a group of
patients presenting with symptoms suggestive of acute
infarction . -
pubmed
METHODS : Twenty - eight
patients presenting to the emergency department with symptoms highly suggestive of acute
infarction were injected with
99mTC - GLA and imaged about 3 h later . -
pubmed
Fourteen
patients with acute
infarction injected within 9 h of onset of
chest pain had positive scans , even in the presence of persistent occlusion . -
pubmed
Nine
patients with negative scans had acute
infarction but were injected more than 9 h after onset of
chest pain . -
pubmed
The final diagnosis in the remaining 5
patients was
unstable angina ( 3 injected & lt;9 h and 2 injected & gt;9 h after onset of
chest pain ) . -
pubmed
The eastern cottontail
rabbit ,
Sylvilagus floridanus ( Allen ) , may play an important role in the epidemiology of
Lyme disease in Missouri . -
pubmed
Isolates of
Borrelia burgdorferi Johnson , Schmid , Hyde , Steigerwalt & amp ; Brenner were made from ticks recovered from
rabbits , making the cottontail
rabbit a key species for further study of the epidemiology of
Lyme borreliosis in Missouri . -
pubmed
The following article analyses the available evidence of
orlistat 's effectiveness in the treatment of
obese patients . -
pubmed
However , the results of the studies can not be easily generalised to
obese patients in a primary care setting , due to limitations concerning the studies ' internal and external validity . -
pubmed
CONCLUSIONS : Based on these studies
orlistat is an efficient pharmacological treatment for
obesity in
patients adhering to a hypocaloric diet . -
pubmed
Ralstonia solanacearum is a plant pathogen that is also a naturally transformable bacterium that can develop the competence state during
infection of its host . -
pubmed
Use of canaliculorhinostomy for repair of
nasolacrimal duct obstruction in a
horse . -
pubmed
Alexithymic characteristics in
children with refractory
hematological diseases . -
pubmed
Fluorescence polarization immunoassay : can it result in an overestimation of
vancomycin in
patients not suffering from
renal failure ? -
pubmed
It has been reported in scientific data that fluorescence polarization immunoassay ( FPIA ) results in overestimation of
vancomycin in
patients with
renal failure . -
pubmed
Increases in
vancomycin levels have also been reported in
patients not suffering from
renal failure (
nonrenal failure patients ) who are receiving
vancomycin therapy for approximately 10 days or more . -
pubmed
Serum
vancomycin peak and trough samples were obtained from 10 adult ( mean age + /- SD : 55.9 years + /- 17.5 )
nonrenal failure patients ( mean ClCr + /- SD : 76.2 mL / min + /- 29.20 ) receiving
vancomycin therapy for at least 10 days . -
pubmed
BSPM with 123 channels was performed in 45
patients with
coronary artery disease (
CAD ) and 25 healthy controls during supine bicycle exercise testing . -
pubmed
Of the 45
patients , 18
patients had anterior , 14 had posterior , and 13 had inferior
ischemia documented by coronary angiography and
thallium scintigraphy . -
pubmed
Using a cut - off value of -10 microV , the ST
depression separated the
patients with
CAD from controls with a sensitivity of 84 % and a specificity of 96 % . -
pubmed
Expression profile of proteins involved in the xenotransplantability of
non - small cell lung cancers into athymic
nude mice . -
pubmed
The aim of this study was to evaluate the expression profile of proteins involved in growing of
human non - small cell lung cancer (
NSCLC ) in athymic
nude mice . -
pubmed
The expressions of 20 gene products in primary
NSCLC of 170
patients were analyzed and the proteins were correlated with the transplantability of the
carcinomas in
nude mice . -
pubmed
There was no relationship between xenotransplantability of
human non - small cell lung cancer in
nude mice and histology , stage or lymph node involvement . -
pubmed
The resulting clusters were correlated with the take rate of the
carcinomas in
nude mice . -
pubmed
We have previously documented that the dose of
trimegestone is the main determinant of the pattern of
bleeding in
women treated with
estradiol ( E(2 ) ) and sequential combined
trimegestone administered in four doses . -
pubmed
The objectives of this study were to test the effect of changing the dose of
trimegestone and the duration of treatment on the pattern of
bleeding in these
women who then entered a 6 month extension phase where a single dose of
trimegestone was given sequentially combined with E(2 ) . -
pubmed
RESULTS :
Women who had received
trimegestone 0.25 mg / day during the first 6 months experienced no change in the
bleeding pattern in the 6 month extension . -
pubmed
Women who had been treated with 0.5 mg / day dose experienced earlier onset , and more prolonged
bleeding ( P & lt ; 0.0001 ) following the change to 0.25 mg / day . -
pubmed
Women who previously received
trimegestone doses of 0.05 and 0.1 mg experienced a later onset of
bleeding , which was lighter and of shorter duration ( P & lt ; 0.001 ) during the extension phase as compared with the first 6 months . -
pubmed
Several clinical trials have determined that
thalidomide is active in 25 - 35 % of
patients with
relapsed myeloma . -
pubmed
The primary end - point of the present study was to investigate whether the alternating combination of
vincristine -
doxorubicin -
dexamethasone (
VAD ) and
melphalan -
prednisone (
MP ) or
vincristine -
mitoxantrone -
dexamethasone (
VND ) and
MP could improve the clinical outcome of
MM patients thus treated in comparison with those receiving
MP alone . -
pubmed
In both younger and elderly
patients , severe
granulocytopenia and related
infections were significantly more frequent with VND /
MP compared to the remaining arms of treatment ( p & lt ; 0.001 and p = 0.009 , respectively ) . -
pubmed
INTERPRETATION AND CONCLUSIONS : Alternating VAD / MP and VND / MP failed to improve the clinical outcome for
MM patients , at the cost of increased toxicity and morbidity . -
pubmed
Ardisiphenols showed moderate scavenging activities toward
1,1 - diphenyl-2 - picrylhydrazyl (
DPPH ) radicals and showed
cytotoxicity against the
murine breast cancer cell line ,
FM3A. -
pubmed
White - coat effect induced by therapist 's presence during speech therapy : study of
post - stroke aphasic Japanese
patients . -
pubmed
OBJECTIVE : To delineate the clinical characteristics of
post - stroke aphasic
patients exhibiting the white - coat effect when a therapist is present during therapy session , 18 Japanese
inpatients were studied . -
pubmed
METHODS : Bronchial biopsy and sputum samples were collected from 120
patients confirmed to have
lung cancer and 40
patients with benign
pulmonary diseases . -
pubmed
A case of necrotizing
fasciitis in a dialysis
patient is described . -
pubmed
Two large phase III studies in
patients with metastatic
colon cancer established at least equivalent efficacy and improved tolerability for
capecitabine compared to the Mayo Clinic bolus
5 - FU /
folinic acid regimen . -
pubmed
Phase II studies established remarkable activity in
women with heavily pretreated metastatic
breast cancer . -
pubmed
Moreover the combination with a
taxane yielded a unique survival benefit compared to the previous gold standard of
taxane monotherapy in a phase III trial of
women with
anthracycline resistant
breast cancer . -
pubmed
The commonest side - effects are
hand and foot syndrome ,
diarrhoea and
stomatitis with serious adverse events occurring in a minority of
patients . -
pubmed
[ Morphological changes of cultured
rabbit retinal cells after
injury ] . -
pubmed
PURPOSE : To investigate the morphological changes of cultured
rabbit retinal cells after
injury . -
pubmed
We report an 8 - year - old
girl with
adhesion ileus complicated with jejunal
perforation . -
pubmed
The
patient developed an
anaphylactic reaction to parenteral nutrition . -
pubmed
METHODS : From 1996 until 2002 , we analyzed 94 consecutive
patients with postoperative
colorectal anastomotic stenosis who were treated endoscopically . -
pubmed
Dilatation was successful in 59 % of
patients resected for
cancer and 88 % resected for a benign condition . -
pubmed
Complications developed in 17
patients ( benign
restenosis ,
perforation ,
abscess ) ; they were significantly more frequent after initial
cancer resection than after resection for a benign condition ( p & lt ; 0.05 ) . -
pubmed
CONCLUSION : High success and low complication rates make endoscopic dilatation the treatment of choice to avoid high - risk reoperations in
patients with benign anastomotic
stricture . -
pubmed
SUBJECTS AND METHODS : The authors analyze their experience with the course of pregnancy and delivery in a
patient with
MDS and
refractory anaemia who was treated on account of the disease for several years before pregnancy in the Institute of Haematology and Blood Transfusion . -
pubmed
Pregnancy was terminated in this
patient on account of
preeclampsia gravis per sectionem caesarean by delivery of a healthy foetus . -
pubmed
Transfer of blood between " tritonized " and normal
rats leads to a disappearance of the
hypercholesteremia in the former and its appearance in the latter
animals . -
pubmed
Escherichia coli as a causative organism of
infantile diarrhoea . -
pubmed
Peripheral
thyroxine metabolism in
patients with psychiatric and
neurological diseases . -
pubmed
CASE SUMMARY : A 47 - year - old white
man receiving combined
mirtazapine and
venlafaxine therapy for
major depressive disorder developed
agitation ,
confusion , severe
shivering ,
diaphoresis ,
myoclonus ,
hyperreflexia ,
mydriasis ,
tachycardia , and
fever on coadministration of
tramadol for
chronic pain . -
pubmed
CONCLUSIONS : It is vital that clinicians are aware of the potential for
SS when psychotropic and nonpsychotropic agents are coadministered to certain
patients , such as those with both
depression and
chronic pain . -
pubmed
Patients with an
alcohol concentration<2 g / l had mostly
soft tissue limb injuries ( 58 % ) , 2 - 2.5 mostly significant
limb fractures ( 55 % ) , and & gt;2.5 mostly significant
head injuries ( 90 % ) . -
pubmed
Thyroid storm most often occurs in
patients with known
thyrotoxicosis . -
pubmed
This report discusses a severe case of
thyroid storm developing as a direct result of
strangulation in a
patient without a preexisting history of
thyroid disease . -
pubmed
Therefore identification of the molecular events underlying
wound repair is essential to develop new effective treatments in support to
patients and the
wound care sector . -
pubmed
METHODS : The present study consisted of 35 eyes ( 34
patients ) with full thickness
corneal opacities and extensive corneal conjunctivalization after severe
corneal burns . -
pubmed
Inherited chondrodysplasia in Texel
sheep . -
pubmed
CASE HISTORY : A
skeletal disease characterised by
dwarfism ,
limb deformity and sometimes
sudden death occurred over a period of 5 years in
lambs born on a commercial
sheep farm in Southland . -
pubmed
CLINICAL FINDINGS : Affected
lambs appeared normal at birth but showed evidence of
dwarfism , wide - based stance and
exercise intolerance as early as 1 week of age . -
pubmed
Some severely - affected
lambs died suddenly of
respiratory embarrassment , probably due to tracheal collapse . -
pubmed
Affected
sheep that survived to breeding age eventually developed severe
degenerative joint disease . -
pubmed
DIAGNOSIS :
Inherited chondrodysplasia of Texel
sheep . -
pubmed
CLINICAL RELEVANCE AND CONCLUSIONS : This
chondrodysplasia differs from those previously described in
sheep and is considered to be a newly - recognised ,
recessively - inherited genetic disease of the Texel breed . -
pubmed
This disease of
sheep may provide a suitable model for studying various forms of therapy for
human chondrodysplasias . -
pubmed
Primary
cutaneous cryptococcosis in a
patient with minimal change
nephrotic syndrome . -
pubmed
In the hippocampal formation of
temporal lobe epilepsy patients , however , this stereotyped pattern of projection is often collapsed ; the mossy fibers branch out of the dentate hilus and abnormally innervate the dentate inner molecular layer , a phenomenon that is termed mossy fiber sprouting . -
pubmed
Experimental studies have replicated this sprouting in
animal models of
temporal lobe epilepsy , including kindling and pharmacological treatment with convulsants . -
pubmed
The influence of muscle type and
dystrophin deficiency on
murine expression profiles . -
pubmed
MATERIAL AND METHODS : A retrospective chart review of 77 previously untreated
patients with
squamous cell carcinomas of the oral cavity with N0 neck from 1988 to 2001 was performed . -
pubmed
The overall neck
recurrence rate in
patients with controlled primary disease was 2.4 % . -
pubmed
No cervical
recurrence occurred in 11
patients treated with SND alone . -
pubmed
Non - invasive detection of latent
cardiac conduction abnormalities in
patients with
pulmonary sarcoidosis . -
pubmed
METHODS AND RESULTS : Ten
patients with
CS , 52
patients with
pulmonary sarcoidosis (
PS ) but no obvious cardiac manifestations and 52 normal controls were studied . -
pubmed
All
participants underwent SAECG to detect
LP . -
pubmed
In 52
patients with
PS ,
LP were detected in 25
patients ( 46.2 % , PS - LP(+ ) group ) , comparing only 3 ( 5.8 % ) of normal controls ( p<0.0001 ) . -
pubmed
CONCLUSIONS : In the
PS patients without obvious cardiac manifestations ,
LP were detected as high as 46.2 % , suggesting latent minute conduction abnormality . -
pubmed
OBJECTIVES : To compare discontinuation rates of atypical antipsychotic agents in
patients with
schizophrenia . -
pubmed
METHOD : Adult Maryland Medicaid
patients with
schizophrenia were categorized based on initial atypical antipsychotic drug received :
aripiprazole ( n=446 ) ;
olanzapine ( n=1705 ) ;
quetiapine ( n=1467 ) ;
risperidone ( n=1580 ) ; and
ziprasidone ( n=700 ) . -
pubmed
In this study we compared the effect of 21 % and 100 % reoxygenation on temporal changes in the plasma level of these factors in newborn
piglets subjected to
hypoxia . -
pubmed
Newborn
piglets were subjected to 2 h
hypoxia followed by 1 h of reoxygenation with either 21 % or 100 %
oxygen and observed for 4 days . -
pubmed
Fanconi anemia (
FA ) patients have an increased risk for
squamous cell carcinomas (
SCCs ) at sites of predilection for
infection with high - risk
human papillomavirus (
HPV ) types , including the oral cavity and the anogenital tract . -
pubmed
We describe a 71 - year - old
man who had received
warfarin 7.5 mg / day for 5 years for
atrial fibrillation , which had maintained his international normalized ratio ( INR ) within a narrow range of 2.5 - 3.2 . -
pubmed
Potential further use of vaccines against
Streptococcus pneumoniae and
nontypeable Haemophilus influenzae means that
M. - pubmed
These findings could indicate that marine
strains of
F. - pubmed
CsA neurotoxicity is the second major problem that seems underestimated especially in case of subtle manifestations in
children . -
pubmed
Electrostimulation to enhance salivary secretion has been used frequently as a research tool but only in limited extent as a clinical method to treat
patients with
xerostomia . -
pubmed
MATERIALS AND METHODS : A Saliwell Crown was placed in the lower third molar area of an 81 - year - old female
patient with complaints of
dry and burning mouth . -
pubmed
CONCLUSIONS : The saliva stimulation device Saliwell Crown , placed on an implant in an 81 - year - old
patient with
dry and burning mouth complaints , presented promising results when both the salivary secretion tests and the self - assessment questionnaires were examined and compared . -
pubmed
3 - Nitropropionic acid (
3 - NP ) is a
plant - based mycotoxin that produces
HD like symptoms in animals . -
pubmed
RESULTS : Fourteen days of
EGCG pretreatment ( 10 , 20 , and 40 mg / kg ) significantly attenuated behavioral alterations , oxidative damage , mitochondrial complex enzymes dysfunction , and
striatal damage in 3 - NP - treated
animals . -
pubmed
The aim of the study was the assessment of therapeutic effectiveness of the phased application of
Rifampicin and electropulse therapy in the treatment of
patients with
psoriasis . -
pubmed
Under observation were 25
patients with
vulgar psoriasis ( 13
women and 12
men aged from 18 to 65 years , with duration of illness from 1 month to 25 years ) . -
pubmed
The effectiveness of treatment in
patients receiving
Rifampicin was the same regardless of the presence or absence of concomitant
bacterial infection , which suggests that the positive therapeutic results of
rifampicin is related not to its antibacterial , but to immunomodulatory effects . -
pubmed
As a conclusion we can say that , the application of electropulse therapy and
Rifampicin phase - treatment in
patients with
psoriasis reduces the period of the normalization of clinical indices for 7 days , as well as 2,5 times reduces the frequency of
relapses in the year . -
pubmed
Patients infected with
human immunodeficiency virus (
HIV ) often progress to
ESRD . -
pubmed
Patients infected with
HIV who also have
ESRD are at risk for critical interactions between medication regimens to treat both of these conditions . -
pubmed
Knowledge of antiretroviral regimens , drug interactions , and
HIV resistance as well as the management of
ESRD in the presence of
HIV infection will improve the care of these unique patients . -
pubmed
On the basis of initial leukocyte count and prognostic factors ,
patients enrolled in this study were divided into three risk groups ( early
relapse , high leukocyte count and standard risk groups ) . -
pubmed
On first year follow - up the
patient had completely recovered with no
neurological deficits . -
pubmed
OBJECTIVE : To observe the effect of combined therapy with Xuezhikang Capsule ( XZK ) and
Valsartan on
left ventricular hypertrophy (
LVH ) and heart rate turbulence ( HRT ) in
hypertensive patients . -
pubmed
METHODS : Ninety primary
hypertensive patients with
LVH were randomly assigned to three groups . -
pubmed
METHODS : A 37 - year - old right - handed
woman became
comatose after a
motor vehicle accident with
cerebral contusions and massive left
cerebral edema . -
pubmed
CONCLUSIONS : The label free QCM based biosensor was successfully developed to diagnose an abnormal
human globin gene causing
alpha - thalassemia 1 (
SEA deletion ) . -
pubmed
In the present study we investigated this and the related process of inhibitory control at the youngest possible age through the study of infant siblings of
children with an
autism spectrum disorder ( Sibs -
ASD ) . -
pubmed
MATERIAL AND METHODS : Retrospective study of seventeen cases of
children who were diagnosed with an
arachnoid cyst during prenatal MRI between July 1994 and January 2007 and followed up for a mean 6 years and 6 months . -
pubmed
RESULTS : Eight of the 17
patients included in this study underwent derivation surgery for the
cyst . -
pubmed
Two of the
children in group 3 present with a
supratentorial cyst , and 4 with a
cyst of the posterior fossa . -
pubmed
Whole - cell voltage - clamp recordings of lamina II neurons were performed in spinal cord slices from
streptozotocin - induced
diabetic rats . -
pubmed
The amplitude of glutamatergic excitatory postsynaptic currents ( EPSCs ) evoked from the dorsal root and the frequency of spontaneous EPSCs ( sEPSCs ) were significantly higher in
diabetic than vehicle - control
rats . -
pubmed
UK-14304 also inhibited the amplitude of evoked monosynaptic and polysynaptic EPSCs more in
diabetic than control
rats . -
pubmed
In addition , intrathecal administration of
UK-14304 increased the nociceptive threshold more in
diabetic than vehicle - control
rats . -
pubmed
BACKGROUND AND AIMS : The Scottish Intercollegiate Guidelines Network ( SIGN ) has published guidelines for the management of
children with
head injuries . -
pubmed
PATIENTS AND METHODS : This monocentric , observational , and retrospective survey was performed on 66 intensive care
patients treated by antibiotics including
vancomycin , alone or in combination , as a curative treatment for a severe
infection with Gram - positive bacteria . -
pubmed
Molecular profiling has allowed a more precise classification of
human cancers . -
pubmed
In addition , this approach can be used to determine the type of
tumor represented by particular cell lines or transgenic
animal models . -
pubmed
Vigabatrin should be considered for rCPS if a
patient has failed appropriate trials of other AEDs or is not a suitable candidate for other AEDs , is not an optimal surgical candidate , and continues to experience debilitating effects from
seizures . -
pubmed
Vigabatrin is indicated as monotherapy for pediatric
patients with
IS . -
pubmed
Its efficacy in achieving improved
seizure control should be apparent within 12 weeks in
patients with rCPS and within 2 - 4 weeks after attaining appropriate dosage for
patients with
IS . -
pubmed
Because 12 weeks is well less than the known time of onset of
visual defects , the risk of developing
pVFDs may be minimized by discontinuing
vigabatrin early during the course of therapy for
patients with inadequate response . -
pubmed
Although some
patients will be at risk of
retinopathy ,
vigabatrin is an appropriate treatment option for
patients who achieve substantial clinical benefit , especially given the severe consequences of
rCPS and uncontrolled
IS . -
pubmed
OBJECTIVES : The purpose of this study was to assess the effect of remote ischemic precondition ( RIPC ) on the incidence of
myocardial and renal injury in
patients undergoing cardiovascular interventions as measured by biomarkers . -
pubmed
Patients receiving RIPC had lower levels of markers of
myocardial injury in the first few days after surgery ( standardized mean difference [ SMD ] , 0.54 ; 95 % confidence interval [ CI ] , -1.01 to -0.08 ; P=.01 ) with highly heterogeneous results ( I2 = 93 % ) . -
pubmed
In
patients undergoing
abdominal aortic aneurysm repair , RIPC when compared to control also decreased
renal injury ( SMD , 0.28 ; 95 % CI , -0.49 to -0.08 ; P=.007 ; I2 = 51 % ) . -
pubmed
Genetic analysis of pathogen - specific clinical
mastitis in Norwegian
Red cows . -
pubmed
The objective of this study was to estimate heritabilities and genetic correlations for
pathogen - specific clinical mastitis (
CM ) in Norwegian
Red cows . -
pubmed
The 4 CM traits were defined as binary and scored as 1 if the
cow had at least 1 case of the
CM in question and 0 otherwise . -
pubmed
aureus
CM , 0.02 for
Strep . - pubmed
The highest genetic correlation was found between unspecific
CM and
Strep . - pubmed
dysgalactiae
CM , whereas the lowest was found for
E. - pubmed
PROCEDURE : A prospective series of 425 patients ( 28 % of them
adolescents ) with solid
tumors was analyzed to investigate the correlation between symptom interval and age , and the different contributions to symptom interval in terms of the time from symptom onset to the first contact with a doctor ( patient delay ) , referral to the oncologist ( referral delay ) , and final diagnosis ( oncologist delay ) . -
pubmed
The experience of our clinic between 2001 and 2011 covers 3500 cases of
patients with
bladder cancer . -
pubmed
Complex mixtures of
polycyclic aromatic hydrocarbons (
PAHs ) are present in air particulate matter ( PM ) and have been associated with many adverse
human health effects including
cancer and
respiratory disease . -
pubmed
It showed unsuspected N3 disease ( infraclavicular , supraclavicular , or internal mammary nodes ) in 40
patients and distant
metastases in 53 . -
pubmed
Inflammatory myofibroblastic tumor is an uncommon
spindle cell tumor , occurring mainly in
children and young adults . -
pubmed
It is an extremely rare
cardiac tumor especially
patients under 1 year . -
pubmed
Development and assessment of a complete - detoxication strategy for
Fuzi ( lateral root of
Aconitum carmichaeli ) and its application in
rheumatoid arthritis therapy . -
pubmed
AA model was established by incomplete Freund 's adjuvant injection in
Wistar rats , and the
animal 's physiological (
body weight , food intake , etc . ) -
pubmed
Indigestible colonic substrates from
brown beans may provide a preventive tool in relation to
obesity and the
metabolic syndrome . -
pubmed
Twenty - five
women with unilateral
endometrioma underwent laparoscopic stripping of the
endometrioma cyst capsule . -
pubmed
PURPOSE : Radiation
pneumonitis is the most severe dose - limiting complication in
patients receiving thoracic radiation therapy . -
pubmed
Tinea corporis occurred more frequently observed when
T. - pubmed
Children with
epilepsy often present with pervasive cognitive and behavioral comorbidities including
working memory impairments ,
attention deficit hyperactivity disorder (
ADHD ) and
autism spectrum disorder . -
pubmed
Some of these
children , particularly those with
epilepsies classified as
Landau - Kleffner Syndrome or continuous spike and wave during sleep , have infrequent
seizure activity but frequent focal
epileptiform activity . -
pubmed
To this end , we have recently developed a
rat model to test the role of frequent focal
epileptiform activity in the prefrontal cortex . -
pubmed
Using microinjections of a
GABA(A ) antagonist (
bicuculline methiodine ) delivered multiple times per day from postnatal day ( p ) 21 to p25 , we showed that
rat pups experiencing frequent , focal , recurrent
epileptiform activity in the form of interictal spikes during neurodevelopment have significant long - term
deficits in attention and sociability that persist into adulthood . -
pubmed
Transcatheter aortic valve implantation ( TAVI ) is a therapeutic option for
patients with severe
aortic valve stenosis and high surgical risk . -
pubmed
Data concerning combined TAVI and percutaneous coronary intervention ( PCI ) as an alternative treatment to surgery in high - risk
patients with
aortic valve stenosis and concomitant
coronary artery disease (
CAD ) are limited , and no prior cases of an emergency procedure in
cardiogenic shock have been described . -
pubmed
Herein is presented the case of a 53 - year - old
patient admitted in
cardiogenic shock due to subacute
myocardial infarction as well as high - grade
aortic valve disease . -
pubmed
We investigated
Chl degradation during
dehydration in both poikilochlorophyllous (
Xerophyta viscosa ) and homoiochlorophyllous (
Craterostigma pumilum ) species . -
pubmed
Epidemiological evidence suggests that the consumption of
fruits and
vegetables may reduce the risk of both
cancer and
cardiovascular disease , and it has been hypothesized that this is due in part to the presence of antioxidant compounds in
fruits and
vegetables . -
pubmed
CONCLUSIONS :
Hypertension is common among
HIV - positive individuals in rural Uganda . -
pubmed
Similar chemopreventative strategies may be useful in
humans who are at high risk of developing H.pylori - induced gastric
adenocarcinoma . -
pubmed
PATIENTS AND METHODS : From January 2011 to August 2014 , 21
patients underwent central quadrantectomy for
carcinoma of the central region of the breast . -
pubmed
Postoperative pathology revealed a
tumor mean safety margin of 2.5 + -0.83 cm , with positive axillary lymph nodes in 15 ( 75.0 % )
patients . -
pubmed
The study of genes associated with
infertility in
rodent models has expanded the field of translational genetics in identifying the underlying cause of
human infertility problems . -
pubmed
Many intriguing aspects of the molecular basis of
infertility in
humans remain poorly understood ; however , application of genetic knowledge in this field looks promising . -
pubmed
The growing literature on the genetics of
human infertility disorders deserves attention and a critical concise summary is required . -
pubmed
CONCLUSIONS : Our findings suggest that the
intestinal parasites infection was prevalent in captive Chinese alligators , and this condition requires our attention , whatever it is for controlling or preventing the intestinal
parasitic disease from spreading to
humans or conservation of this endangered species . -
pubmed
The prognostic role of
inflammation and hormones in
patients with
metastatic cancer with
cachexia . -
pubmed
Forty - six
patients diagnosed with
cancer cachexia and 34 healthy controls were included in the study . -
pubmed
There were 36 male and 10 female
patients in the
cachexia group , and 24 male and 10 female
patients in the control group . -
pubmed
In vivo growth delay studies in the subcutaneous
colon adenocarcinoma CT26.WT murine model were conducted at a photosensitizer dose equal to 0.5 and 0.2 MTD50 for
TLD1411 and
TLD1433 , respectively . -
pubmed
The recombinant
adenovirus was then delivered into the
tumor - bearing
rats and the results showed that such treatment significantly reduced the volumes of
gliomas and improved the survival of the transplanted
rats . -
pubmed
Impact of
Acute Kidney Injury on Early to Long - Term Outcomes in
Patients Who Underwent Surgery for
Type A Acute Aortic Dissection . -
pubmed
We investigated the incidence and risk factors for
AKI in
patients with
TA -
AAD and its impact on their outcomes . -
pubmed
Postoperative
AKI was observed in 165
patients ( 44.0 % ) . -
pubmed
METHODS :
Patients with H&N
cancer receiving RT as primary treatment were recruited . -
pubmed
By
mice tail amputation model and
blood coagulation timing experiment , it is showed that this chitosan accelerated the tail hemostasis by 55 % and shortened the blood clotting time by 38 % . -
pubmed
Although
multiple sclerosis is a uniquely
human disease , many pathological features can be induced in experimental
autoimmune encephalomyelitis (
EAE ) models following induction of central nervous system - directed autoimmunity . -
pubmed
However , the failure to translate many treatments from
EAE into
human benefit has led some to question the validity of the
EAE model . -
pubmed
Without
EAE and other
animal studies , clinical investigations will continue to be " look - see " exercises , which will most likely provide more misses than hits and will fail the people with
MS that they aim to serve . -
pubmed
METHODS :
Patients included had primary
cutaneous melanoma , Breslow thickness of 2.01 - 4.0 or & gt;4 mm with or without
tumor ulceration ( T3a , T3b , T4a , T4b ) . -
pubmed
Relationship between physical activity and function in elderly
patients discharged after surgical treatment for
gastrointestinal cancer . -
pubmed
[ Subjects and Methods ] The study participants were 18 elderly
patients who underwent surgical treatment for
gastrointestinal cancer [ 10 males and 8 females , aged 71.4 + - 4.2 years ( mean + - SD ) ] . -
pubmed
A total of 8
patients with
high - grade NCL treated at our institution from 1992 to 2014 were identified . -
pubmed
Primary
tumor location was supraglottic in 7
patients and glottic in 1
patient . -
pubmed
Locoregional
recurrence followed by distant
metastasis occurred in 6
patients . -
pubmed
To our knowledge , this is the largest series of
patients with high - grade
NCL treated at a single institution . -
pubmed
Relaxing effect of a new
ruthenium complex
nitric oxide donor on airway smooth muscle of an experimental model of
asthma in
rats . -
pubmed
Protocol for PIT : a phase III trial of prophylactic irradiation of tracts in
patients with
malignant pleural mesothelioma following invasive chest wall intervention . -
pubmed
These invasive procedures encourage
tumour cell seeding at the intervention site and
patients can develop
tumour nodules within the chest wall . -
pubmed
The T - plasty : a modified YV - plasty for highly recurrent
bladder neck contracture after transurethral surgery for benign
hyperplasia of the prostate : clinical outcome and
patient satisfaction . -
pubmed
OBJECTIVE : To describe a modified surgical technique for treatment of highly recurrent
bladder neck contracture (
BNC ) after transurethral surgery for benign
hyperplasia and to evaluate success rate and
patient satisfaction of this novel technique . -
pubmed
Patient reported functional outcomes were retrospectively analysed using a standardized questionnaire assessing
recurrence of
stenosis ,
incontinence , satisfaction and changes in quality of life ( QoL ) . -
pubmed
The evaluation of myocardial function of
patients in the early stage of
acute ischemic stroke by two - dimensional speckle tracking echocardiography . -
pubmed
METHODS : We included 29
patients with
acute ischemic stroke , in whom NIHSS scores were calculated and
stroke infarct volumes recorded . -
pubmed
A novel biologically active acid stable liposomal formulation of
docosahexaenoic acid in
human breast cancer cell lines . -
pubmed
Docosahexaenoic acid (
DHA ) , a component of
fish oil , is known to suppress
rat mammary
carcinogenesis , reduce cell growth and induce apoptosis in
human breast cancer cell lines . -
pubmed
METHODS : We developed an acid stable liposome formulation of
DHA by utilizing
ether and
phytanyl lipids similar in structure to those found in Archaea , known to endure high acidity and temperature ; we compared its biological activities with free
DHA in
human breast cancer cells . -
pubmed
The Clinical Global Impressions Scale Modified for Substance Use ( CGI - SU ) in
patients with
bipolar disorder . -
pubmed
Organ - sparing interventions also led to high
patient satisfaction rates , but contain the risk of symptom
recurrence . -
pubmed
CT26 colon cancer mouse model was developed to study whether the combination of RT and GNPs reduced
hypoxia - induced radioresistance . -
pubmed
Interspecific cooperation : enhanced growth , attachment and
strain - specific distribution in biofilms through
Azospirillum brasilense -
Pseudomonas protegens co - cultivation . -
pubmed
Randomized controlled clinical trial assessing the effects of oral nutritional supplements in postoperative
gastric cancer patients . -
pubmed
BACKGROUND : Postoperative
weight loss and
malnutrition are major issues in
gastric cancer patients . -
pubmed
We investigated the effects of ONS administration on postoperative body
weight loss in
patients with
gastric cancer who had undergone total gastrectomy or distal gastrectomy . -
pubmed
The effectiveness of pre - discharge educational programs on adherence to medication regimens and
relapse of
schizophrenic patients . -
pubmed
Epigenetic alterations underlie various
human disorders , including
cancer , and this has resulted in the development of drugs targeting epigenetic alterations . -
pubmed
In the periodontopathogen
Tannerella forsythia , several proposed virulence factors carry
strain - specifically either a
pseudaminic or a
legionaminic acid derivative as terminal
sugar on an otherwise structurally identical , protein - bound
oligosaccharide . -
pubmed
Image Gallery : Immunocompromised patient presenting with
inguinal rash : a case of
Scedosporium apiospermum . -
pubmed
Suppressive effects of the expectorant drug
ambroxol hydrochloride on
quartz - induced
lung inflammation in
F344 rats . -
pubmed
In the present study , we evaluated modulatory effects of
ambroxol hydrochloride on
quartz - induced
lung inflammation in
F344 rats . -
pubmed
At 120 ppm ,
ambroxol hydrochloride significantly decreased individual
lung inflammation scores for
pulmonary edema and lymph follicle proliferation around the bronchiole , as well as the total
inflammation score , in
quartz - treated
rats . -
pubmed
This mini - review will discuss the clinical manifestations and management of
children with
ARPKD liver disease . -
pubmed
Efficacy of Atypical Antipsychotics in the Management of Acute
Agitation and
Aggression in Hospitalized
Patients with
Schizophrenia or
Bipolar Disorder : Results from a Systematic Review . -
pubmed
Among available approaches , we discuss in detail recent evidence supporting the use of intramuscular ( IM ) antipsychotics and some recently approved oral atypical antipsychotics for the management of acute
aggression and
agitation in hospitalized
patients with
bipolar disorder or
schizophrenia presenting with acute
agitation or
aggression , highlighting some differences between individual antipsychotic agents . -
pubmed
Conclusions : A highly structured algorithm - guided treatment is associated with shorter times and fewer medication changes to achieve remission with
depressed inpatients than treatment as usual or computerized medication choice guidance . -
pubmed
Vitamin D - deficient
mice have more invasive
urinary tract infection . -
pubmed
To determine if
vitamin D had further protective mechanisms during
urinary tract infections , we therefore used a
mouse model . -
pubmed
The
patients ' clinical course is then typically complicated by ongoing
inflammation , protein catabolism , and marked haemodynamic perturbation . -
pubmed
[ Treatment outcome , survival and their risk factors among new
tuberculosis patients co - infected with
HIV during the
Ebola outbreak in Conakry ] . -
pubmed
BACKGROUND : Adjuvant chemotherapy is controversial in
patients with locally advanced
rectal cancer after preoperative chemoradiation . -
pubmed
PATIENTS AND METHODS : VN and the NAR were applied to 158 consecutive
patients with locally advanced
rectal cancer treated with chemoradiation followed by surgery . -
pubmed
The objective of this study was to evaluate the utility of serial radiographs in the clinical outcome of
children with stable distal radius buckle
fractures . -
pubmed
Serial radiographs did not appear to change the excellent clinical outcome for
children with distal radius buckle
fractures . -
pubmed
After VinV - TAVR procedure , 4 ( 2 % )
patients suffered from & gt;= moderate
AR . -
pubmed
Coronary obstruction was observed in 4 ( 2 % )
patients . -
pubmed
Major
bleeding and cerebrovascular complications ( according to VARC ) were reported in 3 ( 1 % ) and 4 ( 2 % )
patients at 30 days . -
pubmed
Residual
stenosis is a common finding which can be observed in 1/4 of
patients undergoing VinV - TAVR . -
pubmed
Enterocytozoon bieneusi genotypes in people with
gastrointestinal disorders in Queensland and Western Australia . -
pubmed
bieneusi in
humans with
gastrointestinal disorders in Queensland and Western Australia . -
pubmed
bieneusi in Australia , to identify possible reservoirs of
human infection , and to assist in the prevention and control of
human microsporidiosis . -
pubmed
Background : The treatment of
patients with severe
glenoid bone loss using reverse total shoulder arthroplasty ( RSA ) is challenging because of the difficulty in obtaining glenoid fixation . -
pubmed
Proteomics of the wheat tan
spot pathogen
Pyrenophora tritici - repentis . -
pubmed
OBJECTIVES : The fungus
Pyrenophora tritici - repentis is a major pathogen of
wheat worldwide , causing the
leaf spotting disease tan
spot . -
pubmed
A survey of proteins secreted by the pathogen into culture filtrate is especially useful , as these are likely to come in direct contact with the
wheat host and may play important roles in
infection / pathogenicity . -
pubmed
METHODS : We performed in vitro experiments in eight
human HNSCC cell lines and a
patient - derived
HNSCC cell line as well as in vivo xenografts in a
human HNSCC cell line . -
pubmed
Understanding the molecular and cellular bases of improved outcomes of subsequent pregnancy may lead to the development of treatment modalities designed for
women at high risk for
pregnancy disorders originating at the maternal - fetal interface . -
pubmed
During phase 2 , the
patient performed without complaining of
LBP , two repetitions of bench press exercise at a load intensity of 1.2 his
body weight and attained 4 min of plank stabilisation . -
pubmed
A 64 - year - old
man had
spasticity of digits 3 and 4 of the right hand for 22 years following a
stroke . -
pubmed
An equibiaxial
strain value of 12 % was applied on
rat PDLCs ( rPDLCs ) . -
pubmed
One of the central mechanisms is molecular mimicry , which is also the most plausible mechanism in the case of
ZIKV - induced
autoimmune disorders . -
pubmed
Thus , it is advised to evaluate and determine
ZIKV exposure and
infection in the management of potential
GBS patients . -
pubmed
Early Sociability and
Social Memory Impairment in the A53 T
Mouse Model of
Parkinson ' s Disease Are Ameliorated by Chemogenetic Modulation of Orexin Neuron Activity . -
pubmed
In this study , we investigated age - related reductions in sociability and social memory in the A53 T
mouse model of
PD . -
pubmed
Moreover , DREADD - induced activation of orexin neurons restores social cognition in the A53 T
mouse model of
PD . -
pubmed
In this study , we identified the A53 T
mouse as a model of social
cognitive impairment in
PD . -
pubmed
Relationship of CHA2DS2 - VASc score to left atrial volume and arterial stiffness in
patients with
atrial fibrillation . -
pubmed
BACKGROUND : Transcutaneous
carbon dioxide measurement ( TcCO2 ) is frequently used as a surrogate for arterial blood gas sampling in adults and
children with
critical illness . -
pubmed
Studies included women 15 - 50 + years from 25 LMIC for indications including
HIV prevention , contraception ,
abnormal bleeding , and menopause . -
pubmed
Gender , age , AO / OTA
fracture type ,
injury mechanism , inter - fragmentary gap , and follow - up time of
patients were recorded . -
pubmed
CONCLUSION :
Patients with comminuted
fractures of the inferior pole of the patella treated with a novel tension band experienced a longer operation time , but earlier partial - weight - bearing and
fracture - healed time , better clinical outcomes at 12 - month follow - up , and less complications . -
pubmed
Offspring of
rats with
cerebral hypoxia -
ischemia manifest
cognitive dysfunction in learning and memory abilities . -
pubmed
Neonatal
hypoxic - ischemic encephalopathy is a serious
neurological disease , often resulting in long - term
neurodevelopmental disorders among surviving
children . -
pubmed
Neonatal hypoxic -
ischemic rat models were established by subjecting the
rats to 8 %
O2 - 92 %
N2 for 2 hours . -
pubmed
These results indicated that the offspring of
hypoxic - ischemic encephalopathy model
rats displayed
cognitive impairments in learning and memory . -
pubmed
Therefore , miR-92 could serve as a potential diagnostic and prognostic marker in
glioma patients . -
pubmed
Circulating inflammatory markers in
cervical cancer patients and healthy controls . -
pubmed
What is unclear still in the potential for modifications of host responses to
human papillomaviruses (
HPV ) - a known causative agent of
CC , that could be induced by cigarette smoking . -
pubmed
The samples were the sera of 43
CC patients and 60 healthy ( NILM ) controls . -
pubmed
Analysis of cardiac magnetic resonance imaging in 36,000
individuals yields genetic insights into
dilated cardiomyopathy . -
pubmed
Toward this goal , we aimed to identify biomarkers associated with
BE and
EAC in
patients . -
pubmed
However , significantly fewer
infants in the
fosphenytoin group had moderate - to - severe
neurodevelopmental delay at the 18- and 24 - month assessments . -
pubmed
Most studies about the efficacy and tolerability conducted so far were performed in adult cohorts , whereas few studies have been performed in
children ; however ,
BRV was proven to be a useful ASM for paediatric
focal epilepsies , with fewer studies and conflicting results among
patients with generalized
epilepsies and
epileptic syndromes . -
pubmed
Retention rates were high in the cohorts analysed , and no serious treatment - emergent adverse events were reported in the majority of
patients , with
somnolence ,
drowsiness ,
irritability ,
aggression and
decreased appetite being the most frequently reported side effects . -
pubmed
Although there are few original papers published on the subject so far , the analysis of the literature data demonstrated the efficacy and safety of BRV in paediatric
patients , with more evidence for
children aged 4 to 16 years with an onset of focal
seizures . -
pubmed
However , a positive response was also achieved in
patients affected by
encephalopathic epilepsies ( e.g Jeavons '
epilepsy ,
Dravet syndrome ,
Lennox Gastaut syndrome and
juvenile myoclonic epilepsy ) , and ongoing studies are now testing BRV in order to widen its application to other forms of
epilepsy and to test its effectivness when used in monotherapy . -
pubmed
Recently resettled refugee populations may be at greater risk for exposure to
severe acute respiratory syndrome coronavirus 2 (
SARS - CoV-2 ) , a virus that causes coronavirus 2019 ( COVID-19 ) , and face unique challenges in following recommendations to protect their health . -
pubmed
Gene ontology analysis of public deposited gene array - based data and validation in our
mouse model showed that the biological process " protein polyubiquitination " is enriched after
CCl4 - induced
liver fibrosis . -
pubmed
Protection of
guinea pigs against primary and recurrent
genital herpes infections by immunization with live heterologous or homologous
Herpes simplex virus : implications for a
herpes virus vaccine . -
pubmed
Guinea pigs , inoculated intravaginally with HSV type 2 develop a primary and spontaneously recurring
genital herpes with clinical symptoms resembling
genital herpes in
humans . -
pubmed
Prior
infection with either subtype of
HSV moderated considerably the
acute disease induced by intravaginal HSV type 2 challenge . -
pubmed
The degree of chimaerism of the coat , bone marrow and cornea in
mouse chimaeras obtained by aggregation of an albino inbred embryo of A
strain with an A X CBA - T6T6 hybrid was investigated . -
pubmed
CPZ was tested here for its ability to inhibit the replication of
Mycobacterium tuberculosis and
Mycobacterium avium in cultured normal
human macrophages , as determined by counts of viable bacteria at 0 , 4 , and 7 days after
bacterial infection of the macrophages . -
pubmed
Role and specificity of T - cell subsets in spontaneous recovery from
Friend virus - induced leukemia in
mice . -
pubmed
Although
rhabdomyosarcoma is predominantly a
malignant disease of
children , it is also seen in adults . -
pubmed
Since adults account for only 15 % of
rhabdomyosarcomas , the experience gathered for the treatment of the
malignancy has been derived from treating
children . -
pubmed
reviewed the clinical histories of 500
patients presenting a
malignant melanoma localized in the head and neck region and treated in their Hospital between 1967 and 1987 . -
pubmed
An open continuation treatment trial was undertaken for
schizophrenic and
schizoaffective patients with
postpsychotic depressions who had manifested favorable responses to initial treatment with adjunctive
imipramine added to their
fluphenazine decanoate and
benztropine regimen . -
pubmed
Of 27
patients enrolled , none had a
psychotic or
depressive relapse , and 23 completed the 6 - month study . -
pubmed
The results therefore support continuation treatment with adjunctive antidepressant medication for those
patients with
postpsychotic depressions who initially respond favorably to this regimen . -
pubmed
Methylene blue can be used to treat
methemoglobinemia in
cats without inducing Heinz body
hemolytic anemia . -
pubmed
Although prolonged treatment of
cats for
urologic syndromes with
MB - containing antiseptics causes Heinz body ( HB )
hemolytic anemia , there is no evidence to suggest that single or repeated therapeutic doses of MB cause
hemolytic anemia . -
pubmed
We investigated the efficacy and safety of MB in reversing
nitrite - induced
MTHB in
cats . -
pubmed
Hemolytic anemia was not observed or demonstrated in any of the
cats groups . -
pubmed
Presentation of one case of gangrenous
cystitis or
vesical gangrene induced by the presence of a large
vesical calculus in a
patient with
neurogenic bladder . -
pubmed
Transesophageal echocardiography was used to study the effect of the balloon inflation on left ventricular function in 20
patients with critical
aortic stenosis undergoing balloon valvuloplasty . -
pubmed
Substance abuse in psychiatric
patients admitted to the emergency room . -
pubmed
Duodenogastric reflux was noted in 10 % of the
patients as compared with 47 % before the operation . -
pubmed
Fasting plasma
glucagon was increased to 0.047 + /- 0.009 nmol / l ( P less than 0.05 ) in the non -
diabetic dehydrated state ( normal 0.026 + /- 0.004 nmol / l ) , and a similar high level of plasma
glucagon was observed in the dehydrated
diabetic rat ( 0.052 + /- 0.020 nmol / l ) , especially after
cortisol treatment . -
pubmed
In the
diabetic rat this ratio was not significantly different . -
pubmed
Thus more catabolic hormonal changes were found in in vivo and in vitro studies in the hyperosmolar
diabetic rat . -
pubmed
Thirty - one
patients suffering from acute frontal
sinusitis were treated by trephination . -
pubmed
Similar findings were obtained in a
rat model of
type I diabetes mellitus induced by
streptozotocin in which glomerular hemodynamic factors appeared important to the development of progressive
renal disease . -
pubmed
Three hundred and fifteen
patients with
anterior uveitis associated with
juvenile chronic arthritis (
JCA ) were studied in order to identify the various risk factors for
uveitis . -
pubmed
Girls were more susceptible to
uveitis than
boys by a ratio of 3:1 . -
pubmed
Patients with pauciarticular onset
JCA had the highest risk of
uveitis and systemic onset patients the least risk . -
pubmed
Sixty
patients with
palmoplantar pustulosis were treated in a double - blind trial with either
acitretin (
etretin ,
Ro 10 - 1670 ) or with
etretinate . -
pubmed
It can be concluded that
acitretin and
etretinate do not significantly differ with regard to efficacy and overall safety in the treatment of
patients with
palmoplantar pustulosis . -
pubmed
Variants of the
R 3230 AC
rat mammary adenocarcinoma were studied , including a subline with increased metastatic potential established by lung colony assay . -
pubmed
Experiments carried out with sensitized
guinea pigs showed a contribution of tracheobronchial C - fibers to the
anaphylactic response . -
pubmed
When
3H - proline was administered to spontaneously
hypertensive ( SHR ) and Wistar - Kyoto ( WKY )
rats , its incorporation into non - collagen protein of the posterior cerebral artery or the mesenteric artery was greater in SHR than WKY . -
pubmed
Administration of
clonidine decreased the rate of incorporation of
3H - proline into the non - collagen protein of these arteries concomitantly with a reduction of blood pressure in each
rat strain . -
pubmed
Administration of
6 - OHDA slightly decreased the incorporation of the
proline into the non - collagen protein of the SHR posterior cerebral artery , but failed to reduce blood pressure in each
rat strain . -
pubmed
Clodronate reduced serum
calcium in 14 episodes and
bone resorption in all
patients . -
pubmed
Clodronate may be a useful measure for controlling
hypercalcaemia and
osteolysis in
patients with
carcinoma . -
pubmed
Results of
genotoxicity testing of
theophylline on
bacteria and two lines of
mammalian cells . -
pubmed
Its potential
mutagenicity was followed at the level of both
bacteria and
mammalian cells . -
pubmed
Occlusion was caused by
atherosclerosis in 43
patients ,
fibromuscular dysplasia in three , chronic dissection in two ,
abdominal aortic coarctation in one , and
neurofibromatosis in one . -
pubmed
Contralateral
renal artery occlusive disease occurred in 22
patients . -
pubmed
Extrarenal
atherosclerosis occurred in 44
patients . -
pubmed
Indication for renal revascularization was
hypertension in 49
patients and preservation of renal function in one . -
pubmed
At hospital dismissal ,
hypertension had improved in 45 of 46
patients . -
pubmed
Thirty - four
patients remained normotensive , five still had less
hypertension , and seven became worse . -
pubmed
These data demonstrate that revascularization of an occluded renal artery can be effective in controlling
hypertension and that this effect is durable in the majority of
patients . -
pubmed
According to a retrospective questionnaire given to 389 students ( 191
girls and 198
boys ) , 50 ( 12.9 % ) had suffered from
OSD . -
pubmed
Cinematographic analysis of the initial motor
syndrome of
audiogenic epilepsy in the
mouse ( Swiss albinos ) . -
pubmed
Proceedings : The
syndrome of acquired
aphasia , EEG abnormalities with or without
convulsive disorder in
children . -
pubmed
A controlled prospective trial was carried out in a group of 80
women undergoing gynaecological surgery and thought to be at risk of developing
postoperative venous thrombosis . -
pubmed
In the
warfarin group , 12 out of 40
patients developed
deep vein thrombosis , six of these episodes being classified as major and six as minor . -
pubmed
In the dextran 70 group , 4 out of 40
patients developed
deep vein thrombosis , all of them minor . -
pubmed
Comparative observations on the production of
fever by
bacterial pyrogens and leucocytic pyrogen in
goats and
rabbits . -
pubmed
[ Beginning of immunity in
swine , inoculated with lapinized swine
plague vaccine ] . -
pubmed
The exposure of
animal neutrophils to crystals implicated in joint
inflammation induces
superoxide and
peroxide generation in a concentration and temperature dependent fashion . -
pubmed
Urinary metabolites of
catecholamines and
indoleamines have been investigated in 16
patients with
anorexia nervosa (
AN ) and 13 controls using a HPLC - method . -
pubmed
In four
patients long - term treatment including parenteral and enteral nutrition together with psychological methods resulted in an increase in the levels of these substances and this correlated with increased
weight gain and urinary
creatinine . -
pubmed
The data indicated that the high rate of cortical
bone resorption in experimental
chicks was not increased above that observed in experimental
chicks was not increased above that observed in control
chicks . -
pubmed
The insufficient mineral mass in
vitamin D - deficient
chicks resulted from the indirect inhibition of bone mineralization due to the low intestinal absorption of
calcium rather than from a change in
bone resorption . -
pubmed
In
vitamin D - treated
chicks the apparent
bone atrophy and net loss of
( 45 ) Ca from bone resulted from inhibiting bone matrix formation and mineralization instead of increasing
bone resorption . -
pubmed
The insect growth regulator
diflubenzuron was found to be a potent inhibitor of melanosome synthesis and release in
mouse melanoma cell cultures , and after three to five successive passages of
melanoma cells in growth medium containing this compound , these cells were unable to produce monolayers in untreated medium and were incapable of inducing
tumor formation in
mice . -
pubmed
67Ga scintigraphy was performed in 42
patients with
pulmonary sarcoidosis and in 30 control subjects . -
pubmed
The pattern of
67Ga accumulation clearly differed in
patients who were radiographically defined as having only
lymphadenopathy and in
patients also having parenchymal involvement . -
pubmed
The morphology of degenerative
hip disease in male breeding
turkeys . -
pubmed
A form of
degenerative joint disease in male breeding
turkeys has been studied . -
pubmed
Of 59 male breeding
turkeys examined at approximately one year of age ,
antitrochanteric lesions were present in all but 5 of them . -
pubmed
Acetone metabolism in
mice : increased activity in
mice heterozygous for
obesity genes . -
pubmed
Mice heterozygous for
obesity - producing mutations , either
obese ( ob/+ ) or
diabetes ( db/+ ) , showed induction of the activity of this pathway to a significantly higher degree than did homozygous normal ( + /+ )
mice of the same
strain . -
pubmed
This more effective conversion of
acetone to
lactate exhibited by heterozygous
mice could account for their prolonged survival on a
starvation regimen compared to that of normal homozygotes . -
pubmed
In
cats the distal and proximal stumps of transected postganglionic bundles of the celiac
ganglion were studied by the Falck -- Hillarp histofluorescence methods 72 hrs after transection . -
pubmed
Surgical adjuvant therapy in
colon carcinoma : a
human tumor spheroid model for evaluating radiation sensitizing agents . -
pubmed
HT-29 human colon
tumor cells growing as spheroids have been evaluated as a model system for measuring the response of
human colon
tumor cell to antineoplastic agents . -
pubmed
The multicellular
HT-29 spheroids develop
hypoxic centers reflecting the cellular conditions found in
human cancer treatment , i.e. -
pubmed
Allopurinol at a concentration of 100 microgram / ml was found to protect these
human colonic carcinoma cells from the
cytotoxic effects of
5 - FU under conditions resembling those found in vivo . -
pubmed
Fine - needle aspiration samples from 54 consecutive
patients suffering from
prostatic benign lesions were analyzed for both cytological diagnosis and DNA cell content , by means of standard cytological criteria and flow cytometry , respectively . -
pubmed
The purpose of this study was to isolate the effects of
glucagon on the intestine by creating a
rat model of segmental mesenteric
ischemia that avoids the systemic
shock associated with total
superior mesenteric artery occlusion and reperfusion . -
pubmed
Control
animals ( n = 8) received normal saline solution ( 10 ml / kg / hr intravenously ) during
ischemia and for 2 hours after declamping . -
pubmed
RESULTS : Compared with nonischemic ileum , the ischemic segment in control
animals showed severe
mucosal injury with a reduction in mucosal thickness to 25 % , epithelial coverage to 23 % , and villar surface ratio to 33 % of that seen in nonischemic ileum ( p & lt ; 0.01 ) . -
pubmed
[ The sensorimotor reactivity of
rats with an initially high
anxiety -
phobia level ] . -
pubmed
Sensorimotor response was measured by acoustic startle reflex in
Wistar male rats with innate high and low levels of
anxiety . -
pubmed
The levels of
anxiety were determined using a complex multiparameter method for evaluating
anxiety - phobic states in
rats by a ranged scale . -
pubmed
Amplitude and prepulse inhibition of the acoustic startle response were increased , but latency of the startle reflex was decreased in
rats with innate high level of
anxiety as compared with those with innate low level . -
pubmed
In
rats with innate high level of
anxiety injection of subconvulsive doses of
pentylenetetrazol ( 10 and 15 mg / kg i.p . ) -
pubmed
Facilitation of acoustic startle in
rats with innate high level of
anxiety is suggested to reflect either a deficit of inhibitory , or intensification of excitatory modulating influences on signal transmission in nerve circuit of acoustic startle . -
pubmed
Studies of the sensorimotor response by acoustic startle in
rats with innate high level of
anxiety are believed to be useful for elucidating basic mechanisms of
anxiety and
phobia . -
pubmed
Arterial puncture and
hematoma were the commonest complications encountered in 8 and 4 per cent of the
patients respectively . -
pubmed
Pneumothorax occurred in two
patients ( 1.6 % ) , while misplacement of catheter tip and
thrombophlebitis was encountered in 0.8 per cent of all cannulations . -
pubmed
Catheter related
bacteremia ( recovery of the same organism from the catheter tip and peripheral blood cultures ) occurred in 31 of these 41
patients ( P & lt ; 0.01 ) . -
pubmed
Of these
patients 194 ( 48 % ) had
calcification in the ligamentum arteriosum including 26 ( 6 % ) with
calcification in the ligamentum arteriosum alone , 108 ( 27 % ) with
atherosclerotic calcification , 11 ( 3 % ) with
granulomatous calcification , and 49 ( 12 % ) with both . -
pubmed
In the study population 169
patients ( 42 % ) had
atherosclerotic calcification , 32 ( 8 % ) had
granulomatous calcification , and 75 ( 19 % ) had both . -
pubmed
The patterns of
calcification for the 26
patients with
calcification of the ligamentum arteriosum alone were curvilinear ( 7
patients , 27 % ) , punctate ( 17 patients , 65 % ) , and clumped ( 2 patients , 8 % ) . -
pubmed
The pattern of
ligamentum arteriosum calcification for the 108
patients with only
atherosclerotic and ligamentum arteriosum calcification was curvilinear ( 28
patients , 26 % ) , punctate ( 32 patients , 30 % ) , and clumped ( 48 patients , 44 % ) . -
pubmed
The patients without any calcifications and the
patients with
ligamentum arteriosum calcification formed one group ( based on their similarity in age , mean 47 years ) with a prevalence of
ligamentum arteriosum calcification of 21 % . -
pubmed
The
patients with
atherosclerotic and ligamentum arteriosum calcification formed a second group ( mean age 71 years ) with a prevalence of
ligamentum arteriosum calcification of 65 % . -
pubmed
Seventy - five percent of the
dogs tested during the acute phase of disease and 100 % of the
dogs tested during
convalescence were seropositive for
E. - pubmed
The geographic , clinical , serologic , and molecular evidence indicates that
granulocytic ehrlichiosis in Minnesota and Wisconsin dogs is not caused by
E. - pubmed
ewingii , but suggests that it is a
zoonotic disease caused by an agent closely related to
E. - pubmed
equi and that dogs likely contribute to the enzootic cycle and
human infection . -
pubmed
In this article , the natural history of
congenital diaphragmatic hernia in
humans is reviewed , and the development of antenatal management strategies is traced . -
pubmed
OBJECTIVE : To investigate
abnormalities of skeletal muscle metabolism in
patients with
congestive heart failure . -
pubmed
During exercise , the degree of
metabolic abnormality is related to the symptomatic status of the
patient . -
pubmed
Approximately 20 % of
patients with
ITP are refractory to
corticosteroids and splenectomy . -
pubmed
Recently ,
pulse high - dose
dexamethasone was reported to be effective in the treatment of chronic
ITP in adult
patients . -
pubmed
We treated 9
patients with severe chronic
ITP with monthly high - dose
dexamethasone . -
pubmed
The standard antiplatelet and antithrombin agents used
today in
patients with
acute coronary syndromes are
aspirin and
heparin . -
pubmed
Low - molecular - weight heparins appear to be beneficial in
patients with
acute coronary syndromes . -
pubmed
Recent trials with
direct thrombin inhibitors in
patients with
acute coronary syndromes have demonstrated modest benefit , but also revealed their narrow therapeutic window and associated risk of
bleeding . -
pubmed
Further trials with novel antiplatelet and antithrombin agents in
patients with
acute coronary syndromes are ongoing . -
pubmed
31P - NMR analysis of
congestive heart failure in the SHHF / Mcc - facp
rat heart . -
pubmed
The SHHF / Mcc - fa(cp ) ( spontaneous
hypertension and
heart failure )
rat is a relatively new genetic model in which all
individuals spontaneously develop
congestive heart failure , most during the second year of life . -
pubmed
4 K with
dobutamine infusion , whereas hearts in end - stage failure were able to increase their RPP from baseline values of 27+/-4 K to only 37+/-7 K. The data indicate that a pronounced decline in
PCr and total
creatine signals the transition from compensatory
hypertrophy to decompensation and failure in the SHF
rat model of
hypertensive cardiomyopathy . -
pubmed
The purpose of this study was to compare the resting heart rates of 10
patients with
panic disorder , 11
patients with
social phobia , and 13 healthy controls during two consecutive visits to our laboratory . -
pubmed
Glomerular filtration rate determination in
diabetic patients using
iohexol clearance -- comparison of single and multiple plasma sampling methods . -
pubmed
The aim of this study was to determine whether single plasma sampling 4 h after injection of
iohexol could accurately determine
GFR in
diabetic patients with mild to moderate
renal failure , compared to multiple plasma sampling . -
pubmed
Single plasma sampling 4 h after bolus injection of
iohexol is a safe and accurate method of determining
GFR and change in
GFR in
diabetic subjects with mild to moderate
renal impairment . -
pubmed
Fifty - nine
patients had at least 4 LM , 62 had an associated
EHL , and 187 had a
surgical margin & lt ; 10 mm . -
pubmed
Haemobartonellosis in
squirrel monkeys (
Saimiri sciureus ): antagonism between Haemobartonella sp . -
pubmed
A hemotropic parasite of the genus Haemo bartonella ( rickettsial parasite of the Family Anaplasmataceae ) is responsible for latent asymptomatic
infection in colony - born
Saimiri monkeys . -
pubmed
In certain
Saimiri monkeys , Haemobartonella
parasitemia remains latent following removal of the spleen . -
pubmed
Latent or patent
haemobartonellosis might raise a problem when
Saimiri monkeys are used as experimental hosts of
Plasmodium falciparum asexual blood stages , as already noticed with " rodent
malaria . " -
pubmed
METHODS : Experimental
TBI was induced in
Sprague - Dawley rats by using a controlled cortical impact device at a velocity of 3 m / second , resulting in a 2 - mm deformation . -
pubmed
Animals treated with
Sm 0.04 % presented a high incidence of
abortion and
stillbirth . -
pubmed
Mapping of two
tumor suppressor genes in the
pig . -
pubmed
Kainic acid ( 12.5 mg / kg ) or saline was injected intraperitoneally into 12 - week - old male
Fischer 344 rats and sacrificed by
decapitation at 4 and 24 h after injection . -
pubmed
METHODS : 50
patients with
dilated cardiomyopathy were randomly assigned to double - blind treatment with 2 I.U. -
pubmed
In order to overcome these limitations , new antifungal compounds are being developed , which may improve our therapeutic armamentarium for prevention and treatment of invasive
mycoses in high - risk
patients with
neoplastic diseases . -
pubmed
This limits the benefits of this therapy and excludes groups of patients such as young
children , the elderly or
hypoglycemia prone
patients . -
pubmed
The intensive therapy and self blood
glucose monitoring ( SMBG ) necessary to limit
hypoglycemia represent a heavy burden for the
patients and their family . -
pubmed
Axial computerized tomography simulation images of 25
patients with
non - small - cell lung cancer were used in this study . -
pubmed
The objective of the current study was to use the
mouse phrenic nerve - hemidiaphragm preparation and botulinum serotype A to investigate 1 ) the relationship of substrate cleavage to toxin - induced
paralysis , and 2 ) the relevance of substrate cleavage to the mechanism of toxin action . -
pubmed
If
animals failed to respond to an altered stimulus , we paired this stimulus with a weak electric
shock during training . -
pubmed
Kinetic analysis of cytokine gene expression in
patients with
GVHD after donor lymphocyte infusion . -
pubmed
Patients who receive a donor lymphocyte infusion ( DLI ) for the treatment of
relapsed leukemia after allogeneic BMT ( alloBMT ) often developed
GVHD . -
pubmed
These results suggest that Th1 dominates in the development of
human clinical
GVHD . -
pubmed
A benign
retroperitoneal schwannoma from a
patient without prior exposure to radiotherapy or chemotherapy was analyzed by chromosome banding after short - term culture . -
pubmed
Thus , our data clearly imply that if
H3 G crosses the BBB with equivalent efficiency to M3 G , then the
myoclonus ,
allodynia and
seizures observed in some
patients dosed chronically with large systemic doses of
HMOR , are almost certainly due to the accumulation of sufficient
H3 G in the central nervous system , to evoke behavioural excitation . -
pubmed
We report the case of a
patient with
anti - GBM disease who initially presented with seronegative
hemoptysis and normal urine . -
pubmed
Brain activation patterns in response to increasing WM processing load ( auditory n - back : 0- , 1- , 2- , and 3 - back conditions ) were assessed with fMRI in 18
MTBI patients within 1 month of their
injury and in 12 healthy controls . -
pubmed
Brain activation patterns differed between
MTBI patients and controls in response to increasing WM processing loads . -
pubmed
MTBI patients showed disproportionately increased activation during the moderate processing load condition , but very little increase in activation associated with the highest processing load condition . -
pubmed
MTBI patients showed a different pattern of allocation of processing resources associated with a high processing load condition compared to healthy controls , despite similar task performance . -
pubmed
Based on the reports of UNSCEAR for the period from 1958 to 2001 the paper presents a retrospective analysis of the use of direct methods and the doubling dose method for quantitative determination of the genetic risk of
human exposure expressed as different
hereditary diseases . -
pubmed
The level of
human natural genetic variability per 1,000,000 newborns is estimated at 738,000 hereditary
diseases including mendelian , chromosomal and multifactorial ones . -
pubmed
The present case was diagnosed as
teratoma in a
feline unilateral cryptorchid testis . -
pubmed
Outcome of lung transplantation in
patients with
mycetomas . -
pubmed
Pulmonary mycetomas are found in
patients with
end - stage lung diseases , especially
sarcoidosis . -
pubmed
Patients were included in our study if
mycetomas were present on the specimens . -
pubmed
RESULTS :
Mycetomas were present in 3.0 % of transplant recipients ( 9 of 303
patients ) . -
pubmed
The underlying pulmonary diagnoses were
sarcoidosis ( six
patients ) , and
emphysema ,
idiopathic pulmonary fibrosis , and
pneumoconiosis ( one patient each ) . -
pubmed
Two
patients died at 17 months and 24 months posttransplant , respectively ; one patient received a second transplant 30 months later ; and two
patients are alive and free from
fungal infections 17 months and 18 months , respectively , after transplantation . -
pubmed
Careful selection of patients and aggressive antifungal therapies before and after transplantation have led to improved outcomes in
patients with
mycetomas . -
pubmed
All
dogs developed
diarrhea , which resolved in all CON
dogs but persisted in all EXT
DEN dogs . -
pubmed
Despite greater
weight loss and persistent
diarrhea in EXT
DEN dogs , at 12 weeks there were no differences in net absorptive fluxes between the EXT
DEN and the CON group after extrinsic denervation . -
pubmed
OBJECTIVE : To compare the perioperative outcome of
patients & gt;or=13 years old undergoing surgery for
congenital heart disease in a
children 's hospital by a dedicated congenital heart surgery and anesthesia team with procedure - matched younger control patients . -
pubmed
All major complications - cardiopulmonary resuscitation ,
neurologic injury , massive
hemorrhage with sternotomy , femoral cannulation for emergent bypass , and severe episodes of
hypotension on induction of anesthesia - occurred in older
patients undergoing repeat sternotomy . -
pubmed
METHODS : Using an autotransplantation
pig kidney model , both early ( 40 min and 7 days ) and late ( 2 - 16 weeks ) changes in renal function and morphology were determined after different periods of
cold ischemia in University of Wisconsin or Euro - Collins solutions . -
pubmed
A 58 - year - old
man was diagnosed as having
type 3 gastric cancer ( poorly differentiated
adenocarcinoma ) . -
pubmed
In the field of
gastric cancer treatment , especially for
patients showing multiple resistance to anticancer drugs , an effective therapy is critically needed . -
pubmed
A
human neuroblastoma cell line (
IMR-32 ) , when differentiated , mimics large projections of the
human cerebral cortex and under certain tissue culture conditions , forms intracellular fibrillary material , commonly observed in brains of
patients affected with
Alzheimer ' s disease . -
pubmed
We have previously studied in vitro differentiation of
murine neuroblastoma (
N1E-115 ) cells with respect to resting membrane potential development . -
pubmed
Sixty
cirrhotic patients and 21 age - matched control subjects without
liver disease were included . -
pubmed
Lymphomas were categorized into
EBV - associated lymphoproliferative disease (
LPD ) and
EBV - negative
non - Hodgkin ' s lymphoma (
NHL ) , and the authors carried out separate analyses of these . -
pubmed
Investigation of the relation of risk of
EBV - negative
NHL to degree of immunosuppression is needed . -
pubmed
Since such an effect was seen in different
animal models of
Parkinson ' s disease (
PD ) , it seems that co - administration of
SCH 58261 may allow for the lowering of the doses of
L - DOPA in clinical practice , which indicates a potential therapeutic value of this compound in the treatment of
PD . -
pubmed
The Golgi complex and melanin elaboration of
human melanomas in tissue culture . -
pubmed
Selecting
girls with
precocious puberty for brain imaging : validation of European evidence - based diagnosis rule . -
pubmed
STUDY DESIGN : A retrospective , multicenter , hospital - based , cohort study was performed , including all
girls with
CPP seen in 7 centers in 6 European countries during given periods . -
pubmed
RESULTS :
Girls with
CPP ( n=443 ) , including 35 with
OICL , were recruited . -
pubmed
Nitric oxide synthesis is increased in the endometrial tissue of
women with
endometriosis . -
pubmed
BACKGROUND : Previous studies have shown that peritoneal macrophages from
women with
endometriosis produce excess
nitric oxide (
NO ) . -
pubmed
RESULTS : Mean ( + /- SEM ) levels of
NO were significantly increased in the endometrial tissues of
women with
endometriosis ( 13.2 + /- 7.8 versus 19.8 + /- 12.6 nmol / g tissue ; P = 0.016 ) . -
pubmed
METHODS : We performed heterologous , left lung transplantation ( +4 degrees C
ischemia ; 24 hours , Euro - Collins solution ) in 6
foxhounds ( untreated ) and in 6 animals that received calf lung surfactant extract ( Alveofact ) prior to explantation ( only donor lung ; 50 mg / kg
body weight ) and immediately after onset of reperfusion ( both lungs , 200 mg / kg
body weight ) . -
pubmed
Studies on
diabetic rats : the effect of
diabetes and of diet upon the plasma and liver lipids of
rats . -
pubmed
We describe a
patient whose testicular parenchyma was displaced by a
cyst . -
pubmed
Combination conformal radiotherapy and radioimmunoguided transperineal 103Pd implantation for
patients with intermediate and unfavorable risk
prostate adenocarcinoma . -
pubmed
PURPOSE : To report outcomes for
prostate cancer patients treated with external beam radiation therapy ( EBRT ) and permanent prostate brachytherapy utilizing radioimmunoguided targeting of biological
tumor volumes ( BTVs ) . -
pubmed
METHODS AND MATERIALS : Between February 1997 and October 2001 , 66
patients with intermediate- to high - risk
prostate cancer underwent EBRT and ProstaScint - guided transperineal brachytherapy . -
pubmed
Patients with intermediate- ( 1 RF ) and high - risk ( 2 - 3 RF )
prostate cancer exhibited 5 - year ASTRO - defined bDFS of 100 % and 81.9 % , respectively . -
pubmed
Among all 26
patients available at postoperative follow - up ( mean 11.9 months ) , the mean loss of
kyphosis correction was 2.0 degree . -
pubmed
Excluded from analysis were 29
patients who required profound hypothermic
circulatory arrest as a result of transverse arch involvement and 26
patients with
aortic rupture , leaving a group of 300
patients for which outcomes were analyzed . -
pubmed
The adjunct group of distal aortic perfusion and
cerebrospinal fluid drainage used in 238 ( 79.3 % )
patients was compared with a group of 62
patients who underwent simple cross - clamp with or without the addition of a single adjunct . -
pubmed
RESULTS : The incidence of
neurologic deficit after all repairs was 2.3 % ( 7 of 300
patients ) . -
pubmed
The incidence of
neurologic deficit ( immediate and delayed ) in the adjunct group was 1.3 % ( 3 of 238
patients ) , and in the nonadjunct group was 6.5 % ( 4 of 62
patients ; p & lt ; 0.02 ) . -
pubmed
All
neurologic deficits occurred in
patients with aneurysmal involvement of the entire descending thoracic aorta ( extent C ; p & lt ; 0.02 ) . -
pubmed
METHODS : We evaluated 564
patients with
rheumatoid arthritis (
RA ) and 155 controls using both techniques . -
pubmed
We present here one such case of
myelofibrosis where the
patient was treated with radiotherapy to the spleen for symptomatic relief . -
pubmed
Helicobacter pylori causes various
gastro - duodenal diseases , including
gastric cancer . -
pubmed
In contrast , recently ill and
chronically ill schizophrenia patients as well as
patients at high risk for
schizophrenia all failed to show this early ERP component while attending to color . -
pubmed
Metabolic control and
nocturnal enuresis in
children with
type 1 diabetes . -
pubmed
This study examined the relationship between metabolic control and
enuresis in
youths with
type 1 diabetes . -
pubmed
Participants were 203
youths with
type 1 diabetes at an outpatient pediatric
diabetes clinic . -
pubmed
The mean fasting blood
glucose ( FBG ) level of
children with
enuresis ( FBG = 192 mg / dl ) was significantly higher than that of
children without
enuresis ( FBG = 160 mg / dl , p = .03 ) . -
pubmed
Subacute stent
thrombosis was detected in 2
patients with failure of FKBI in the classic crush group ( 4.3 % ) . -
pubmed
CONCLUSIONS : Compared with classic crush , DK crush has the potential to improve the clinical outcome in
patients with
coronary bifurcation lesions . -
pubmed
We assessed the outcome of 170
patients with
AML in first complete remission , aged 1 - 47 years ( median 29 ) , who had undergone an allogeneic BMT before or after 1990 ( n=80 and n=90 , respectively ) ; all
patients were prepared with
cyclophosphamide and
TBI ; the median follow - up for surviving
patients was 13 years . -
pubmed
Patients transplanted after 1990 were older , had a shorter interval diagnosis - BMT , had less FAB - M3 cases , received a higher dose of
TBI , a higher marrow cell dose and combined (
cyclosporine+
methotrexate )
GVHD prophylaxis . -
pubmed
We investigated the effects of a continuous administration of high doses of
selenium in
septic shock patients . -
pubmed
METHODS : A prospective , multicentre , placebo - controlled , randomized , double - blind study was performed with an intention - to - treat analysis in severe
septic shock patients with documented
infection . -
pubmed
CONCLUSION : Continuous infusion of
selenium as
sodium selenite ( 4,000 microg on the first day , 1,000 microg / day on the nine following days ) had no obvious
toxicity but did not improve the clinical outcome in
septic shock patients . -
pubmed
RECENT FINDINGS :
Children with
inflammatory bowel disease are at risk for more difficulties in psychosocial functioning than healthy children , particularly
depression ,
anxiety and social difficulties . -
pubmed
One pilot study suggests psychotherapy is effective for depressed
adolescents with
inflammatory bowel disease . -
pubmed
The vascular delivery paradigm found successful in the
mouse was carried to the non -
human primate to test its potential translation to
boys with
DMD . -
pubmed
In this prospective study , we estimated the prevalence of
restless legs syndrome (
RLS ) in
multiple sclerosis (
MS )
patients , and compared the extent of
brain and cervical cord damage between
patients with and without
RLS using conventional and diffusion tensor magnetic resonance imaging ( MRI ) . -
pubmed
Eighty - two consecutive
MS patients were evaluated . -
pubmed
Thirty subjects had
RLS ; they showed a higher Expanded Disability Status Scale score than
patients without . -
pubmed
Cervical cord average FA was significantly reduced in
MS patients with
RLS compared to those without . -
pubmed
BACKGROUND :
Intussusception remains a common cause of
bowel obstruction in young
children and results in significant morbidity and mortality if not promptly treated . -
pubmed
METHODS :
Children treated for
intussusception over a 15 - year period were reviewed after treatment at a tertiary
children 's hospital . -
pubmed
RESULTS : Two hundred forty - four
children with
intussusception were identified . -
pubmed
One hundred forty
children required surgical intervention for
intussusception with 50 % requiring bowel resection . -
pubmed
Interestingly , the suppressors had very different effects on crucifer - infecting Tobamovirus (
crTMV )
infections . -
pubmed
's assertions that the Siberian " ice viruses " are most closely related either to
avian influenza virus or to
human influenza virus strains from Asia from the 1960s ( Zhang et al . -
pubmed
Efficacy and safety of
OCTANINE F in
children with
haemophilia B. -
pubmed
The primary objective of this trial was to investigate the immunogenicity of
OCTANINE F in
children aged & lt;6 years with
haemophilia B. -
pubmed
Twenty - five
children aged & lt;6 years with moderate or severe
haemophilia B , including six who were previously untreated and 13 who had less than previous 50 exposure days were assigned to prophylactic or on - demand treatment with
OCTANINE F over a 12- to 24 - month period . -
pubmed
[ Anesthesia for a
patient with
stiff - person syndrome ] . -
pubmed
The authors reported here a case of an axilally lymphadenectomy in a 46 - year - old
woman with
stiff - person syndrome . -
pubmed
Quantifying
hepatitis C transmission risk using a new weighted scoring system for the Blood - Borne Virus Transmission Risk Assessment Questionnaire ( BBV - TRAQ ): applications for community - based
HCV surveillance , education and prevention . -
pubmed
BACKGROUND : The
hepatitis C virus (
HCV ) is a major cause of drug - related morbidity and mortality , with incidence data implicating a wide range of
HCV transmission risk practices . -
pubmed
rotata aqueous extract ( LRAE ) was given to
mice at concentrations of 0.5 , 1.0 , 2.0 g / kg
body weight and 0.75 , 1.5 , 3.0 g / kg to
rats . -
pubmed
A 74 - year - old
man with
hypertension presented with foamy urine and intermittent right upper quadrant
abdominal pain . -
pubmed
The medial longitudinal fasciculus ( MLF ) is a key brainstem pathway for ocular adduction and is commonly injured in
patients with
MS , typically resulting in
internuclear ophthalmoparesis . -
pubmed
Patients Six
patients with chronic , unilateral , or
bilateral internuclear ophthalmoparesis and 10 healthy control subjects . -
pubmed
METHODS : A total of 213 elderly
patients were divided into 4 groups according to the criteria defined by the American College of Chest Physicians/ Society of Critical Care Medicine ( ACCP / SCCM ) , namely the non -
sepsis group ( group A ) ,
sepsis group ( group B ) , severe
sepsis group ( group C ) and
septic shock group ( group D ) . -
pubmed
Strains of
Escherichia coli ,
Zymomonas mobilis , and non -
Saccharomyces yeasts were unable to surmount the 2 %
butanol growth barrier . -
pubmed
Several
strains of
Saccharomyces cerevisiae exhibit limited growth in 2 %
butanol , while two
strains of
Lactobacillus were able to tolerate and grow in up to 3 %
butanol . -
pubmed
METHODS : A total of 1,286
children ( 6 - 12 yr ) were clinically examined for
goitre from study areas of Imphal east district . -
pubmed
PURPOSE : To assess the outcome of urologic evaluation in
patients with
voiding dysfunction due to
multiple sclerosis (
MS ) and to determine the relationship between urological and neurological parameters of these
patients . -
pubmed
MATERIALS AND METHODS : We retrospectively reviewed the medical records of 249 consecutive
patients ( 162 female and 87 male ) with
MS who were referred to our clinic between 1991 and 2006 , with a median time of 4 years ( range 3 months to 26 years ) of
MS onset . -
pubmed
RESULTS : All
patients except 13 had
lower urinary tract symptoms and 70 % manifested mixed symptoms . -
pubmed
Urodynamic evaluation of 75
patients ( 30.1 % ) revealed
detrusor overactivity with or without
detrusor - sphincter dyssynergia in 56 ( 75 % ) . -
pubmed
CONCLUSIONS : The prevalence of mixed symptoms in
patients with
MS is higher than storage or voiding symptoms alone . -
pubmed
PATIENTS AND METHODS : One hundred and ninety - two
patients with complex / staghorn
renal calculi who were treated with PCNL requiring multiple tracts were included in the study . -
pubmed
Infections with influenza A viruses are still a major threat to
humans and several animal species . -
pubmed
The occurrence of highly pathogenic
avian influenza viruses capable of infecting and killing
humans highlights the urgency for a new and efficient strategy for the treatment of diseases caused by the virus . -
pubmed
The administration of
AL-1 by oral gavage to
mice infected with
avian influenza A / Chicken / Guangdong / 96 ( H9N2 ) ,
A / Duck / Guangdong / 99 ( H5N1 ) , and
human influenza A / PR / 8 / 34 ( H1N1 ) viruses greatly reduced the
death rate , prolonged life , inhibited lung consolidation , and reduced viral titers in the lung . -
pubmed
The LD(50 ) of
AL-1 was 1243 mg / kg / d.
AL-1 was effective against
avian influenza A ( H9N2 and H5N1 ) and
human influenza A H1N1 viruses in vitro , with the 50 % effective concentrations ranging from 7.2 to 15.2 microM and the selective indexes ranging from 51 to 109 . -
pubmed
Evaluation of the use of prognostic information for the care of
individuals with
venous leg ulcers or
diabetic neuropathic foot ulcers . -
pubmed
Chronic colitis (
CC ) was induced in
BALB / c mice using dextran
sodium sulfate . -
pubmed
PROCEDURES : Groups 1 - 4 of
nude mice bearing
human breast carcinoma were injected with
phosphate - buffered saline ,
TRA-8 ,
bevacizumab , and TRA-8 +
bevacizumab on day 0 , respectively . -
pubmed
OBJECTIVE : We describe the case of a young male
patient with invasive
ductal breast carcinoma . -
pubmed
MATERIALS AND METHODS : Diffusion - weighted imaging data from 11
patients ( M : F = 7 : 4 , aged from 1 to 22 years , mean = 12.3 years ) who visited the
epilepsy clinic and received a routine
seizure protocol MRI exam were retrospectively analyzed . -
pubmed
Rotavirus incidence and genotype distribution before and after national
rotavirus vaccine introduction in Belgium . -
pubmed
pneumoniae
infection , suggesting that
S. - pubmed
After detailed investigations , the final adjudicated diagnosis was
acute coronary syndrome in 30
patients ( including acute
myocardial infarction in 13 and
unstable angina in 17 ) and
non - acute coronary syndrome in 28
patients . -
pubmed
Mechanical properties of single
bovine trabeculae are unaffected by
strain rate . -
pubmed
Anxiety and
depression are two of the most prevalent clinical manifestations of
patients with
CP /
CPPS , and have adverse effects on the health of the subjects and prognosis of comorbidities . -
pubmed
Of the 77
patients with
CP /
CPPS , 48 ( 62.3 % ) , 5 ( 6.5 % ) , and 1 ( 1.2 % ) had
anxiety symptoms ,
depression symptoms , or both
anxiety and
depression symptoms , respectively . -
pubmed
Ventricular and supraventricular arrhythmias and
heart failure in a
patient with
left ventricular noncompaction and
Brugada syndrome . -
pubmed
Upon
infection and development within
human erythrocytes ,
P. - pubmed
A 34 - year - old Nigerian
man presented with
nephrotic syndrome . -
pubmed
The rate of complete
tumor blockade [ FES standardized uptake value ( SUV ) & lt;=1.5 ] following
TAM ( 5/5
patients ) was greater than the blockade rate following
FUL ( 4/11 ; 2 - sided mid P = 0.019 ) . -
pubmed
Gender differences in UV - induced
inflammation and immunosuppression in
mice reveal male unresponsiveness to UVA radiation . -
pubmed
Immunosuppression attributed mainly to the UVB ( 290 - 320 nm ) waveband is a prerequisite for
skin cancer development in
mice and
humans . -
pubmed
This could explain the known gender bias in
skin cancer development in both
mice and
humans . -
pubmed
Re : An inducible model of abacterial
prostatitis induces antigen specific inflammatory and proliferative changes in the
murine prostate . -
pubmed
OBJECTIVE : To evaluate the prevalence of
pulmonary embolism(
PE ) in
patients with
chronic obstructive pulmonary disease (
COPD ) exacerbations of unknown origin and to explore the risk factors associated with
PE . -
pubmed
METHODS : A total of 208 consecutive
patients with
COPD were referred to this hospital for severe exacerbations of unknown origin . -
pubmed
RESULTS : The frequency of
PE was 33 % in this series of 208 consecutive
patients with
COPD referred for exacerbations of unknown origin . -
pubmed
CONCLUSIONS : This study showed a 33 % prevalence of
PE in
patients with
COPD who were hospitalized for severe exacerbations of unknown origin . -
pubmed
abortus 2308 from organic
hydroperoxide stress in in vitro assays , this protein is not required for the wild - type virulence of this
strain in cultured
murine macrophages or experimentally infected
mice . -
pubmed
Renal impairment is known to increase
rivaroxaban - associated
bleeding risk in
patients . -
pubmed
These results were obtained during
Sisymbrium officinale seed imbibition in the absence of endosperm
rupture . -
pubmed
[ Clinical analysis of
hepatitis B virus mutations related to
adefovir dipivoxil among patients with
chronic hepatitis B virus infection in eastern Zhejiang province ] . -
pubmed
OBJECTIVE : To explore the clinical characteristics of hepatic B virus (
HBV ) mutations related to
adefovir dipivoxil (
ADV ) among patients with chronic
HBV infection in eastern Zhejiang province and provide some reference values on normative usage of antiviral drugs . -
pubmed
METHODS : The data of chronic
HBV - infected patients with
HBV mutations related to
ADV ( n = 88 ) and non - mutation ( n = 202 ) from June 2008 to August 2010 were analyzed retrospectively . -
pubmed
CONTEXT : Nonspecific changes ( nonspecific
chronic inflammation ) in
patients with
chronic diarrhea represent the commonest diagnosis in colorectal biopsy interpretation , but these changes are of little clinical significance . -
pubmed
DESIGN : Detailed clinical features and histologic findings were analyzed in a cohort of 47
patients with
chronic diarrhea , with near - normal histology and no clear - cut known etiologic agent . -
pubmed
CONCLUSIONS : Lymphocytic follicles and aggregates
colitis , previously regarded as of negligible diagnostic significance , allows the prediction of the behavior of
chronic diarrhea in a subset of
patients with nonspecific changes on colonic biopsy . -
pubmed
Semiquantitative analysis of brain metabolism in
patients with
paraneoplastic neurologic syndromes . -
pubmed
PURPOSE : The objective of this study was to evaluate brain metabolism with
F - FDG - PET in
patients with definite or possible
paraneoplastic neurologic syndromes (
PNS ) using qualitative assessment and semiquantitative measurements with subsequent correlation with MRI . -
pubmed
A prospective PET database of
patients referred for PNS between 2001 and 2010 was queried retrospectively and identified 102
patients who met the diagnostic criteria for
PNS , had PET brain imaging , and lacked clinical or MRI evidence of an alternative diagnosis . -
pubmed
Both qualitative and semiquantitative analyses of brain
glucose metabolism may be helpful in evaluating
PNS , especially in
patients with a normal MRI . -
pubmed
Elevated T - wave alternans predicts nonsustained
ventricular tachycardia in association with percutaneous coronary intervention in
ST - segment elevation myocardial infarction (
STEMI )
patients . -
pubmed
We examined whether T - wave alternans ( TWA ) level is correlated with nonsustained
ventricular tachycardia (
NSVT ) incidence in association with PCI in
patients with acute
ST - segment elevation myocardial infarction (
STEMI ) . -
pubmed
METHODS AND RESULTS : We analyzed continuous 24 - hour ambulatory electrocardiograms in 48
STEMI patients during and after successful primary PCI , achieving
Thrombolysis in Myocardial Infarction ( TIMI ) grade 3 flow . -
pubmed
Maximum TWA was elevated in
patients with ( N = 22 ) compared to without ( N = 26 )
NSVT ( 75.1 + - 6.3 vs 49.9 + - 3.6 muV , P & lt ; 0.005 ) during the 22 - hour monitoring period . -
pubmed
Here we injected brain extracts from
humans who had died with various
tauopathies into the hippocampus and cerebral cortex of ALZ17
mice . -
pubmed
Similar inclusions also formed after intracerebral injection of brain homogenates from
human tauopathies into nontransgenic
mice . -
pubmed
Subcutaneous specific immunotherapy was performed in 57 ( 70.3 % )
allergic patients . -
pubmed
For the treatment of the developed
rhinitis , we used intranasal
glucocorticosteroids in all 47 ( 37.9 % )
patients with
rhinitis medicamentosa . -
pubmed
Only 5 ( 17.2 % )
patients with specific immunotherapy developed
rhinitis medicamentosa . -
pubmed
Specific immunotherapy is recommended for the prevention of
rhinitis medicamentosa in
patients suffering from
allergic rhinitis , whereas intranasal
glucocorticosteroids are the most appropriate for the treatment regardless initial cause of
rhinitis development . -
pubmed
Potentiation of
cytotoxicity of
paclitaxel in combination with
Cl - IB - MECA in
human C32 metastatic
melanoma cells : A new possible therapeutic strategy for
melanoma . -
pubmed
Our aim was to investigate a possible combinatory therapeutic strategy using
PXT and
Cl - IB - MECA on
human C32 melanoma cells and its underlying mechanisms . -
pubmed
SUMMARY : Methods for the evaluation and management of
patients with
zygomatic fractures continue to evolve . -
pubmed
It is the purpose of this Maintenance of Certification article to provide updated recommendations for preoperative assessment , surgical care , and postoperative management of
patients with
zygomatic fractures . -
pubmed
In 10 chronically instrumented
dogs ,
congestive heart failure (
HF ) was induced by high - frequency cardiac pacing . -
pubmed
Patients on three or more antihypertensive drugs , with systolic BP values above & gt;=160 mmHg ( & gt;=150 mmHg for
patients with
type 2 diabetes ) are classified as having resistant
hypertension . -
pubmed
METHODS : One hundred
neonates with
NRDS were divided into NIPPV group ( n=50 ) and nasal continuous positive airway pressure ( NCPAP ) group ( n=50 ) . -
pubmed
The results demonstrated the enhancement of the bone repair effects of ExCNFs by
BMP in a
rat femoral fracture model . -
pubmed
PERFORM : a system for monitoring , assessment and management of
patients with
Parkinson ' s disease . -
pubmed
In this paper , we describe the PERFORM system for the continuous remote monitoring and management of
Parkinson ' s disease (
PD )
patients . -
pubmed
This was done using skeletal muscle samples from
men subjected to physiological conditions often investigated in applied physiology where the intervention has been suggested to impede normalization ( ageing ,
muscle atrophy , and different muscle fiber type composition ) . -
pubmed
Pre - operative variables included the
patients ' age , sex , the affected side , cause of
injury , Tscherne classification of
soft tissue injury ,
fracture pattern , and time from
injury to surgery . -
pubmed
BACKGROUND : Although radiotherapy is a key component of curative - intent treatment for locally advanced , unresectable
non - small cell lung cancer (
NSCLC ) , it can be associated with substantial
pulmonary toxicity in some
patients . -
pubmed
[
Oral ulcer as primary manifestation of
HIV infection in an 80 - year - old
man ] . -
pubmed
Oral lesions such as
candidiasis ,
Kaposi ' s sarcoma ,
hairy leukoplakia ,
herpes simplex infection , and
ulcerative periodontitis are associated with
HIV infection and may be the primary presentation in persons with undiagnosed
HIV . -
pubmed
We report a clinical case in which an 80 - year - old
man presented with an
oral ulcer with morphological signs of immuno - suppression . -
pubmed
The patient was perceived to be at low risk of
HIV infection and thus , diagnostic
HIV testing was delayed until subsequent development of
Kaposi ' s sarcoma on the skin . -
pubmed
METHODS : Male
SD rats were randomly divided into normal group and model group , which were administrated with high fat diet to establish
nonalcoholic steatohepatitis model . -
pubmed
At the end of the 4th or the 12th week , lipid droplets in the model
rat liver cells were heavily dyed red and
hepatic steatosis increased severely , with ballooning degeneration of liver cells . -
pubmed
Superspectra created in this study enabled correct identification of 86
strains belonging to different subspecies of
S. - pubmed
The aim of the current study was to examine whether there are differences in initial threat reactivity and the time course of threat responding during predictable and unpredictable threat - of -
shock in 186
adults with : 1 ) current
PD and no history of
depression ( i.e. -
pubmed
We measured preoperative psychological distress and substance use , and then measured
pain and opioid use after surgery until
patients reported the cessation of both opioid consumption and
pain . -
pubmed
Polysaccharide
Agaricus blazei Murill ( pAbM ) has been found to have anti -
cancer activity , but the underlying mechanism of this is poorly understood . -
pubmed
In addition to , pAbM did not inhibit
tumour growth in
TLR2 (-/- ) mice . -
pubmed
Reduced skeletal muscle quantity and quality in
patients with
diabetic polyneuropathy assessed by magnetic resonance imaging . -
pubmed
METHODS : MRIs of the tibialis anterior ( TA ) muscle were recorded from 9
individuals ( 5
men ) with
DPN ( ~65 years ) and 8 ( 4
men ) age- and gender - matched controls . -
pubmed
Magnesium sulfate prevents maternal
inflammation - induced
impairment of learning ability and memory in
rat offspring . -
pubmed
The shuttle box is divided in half and the
animal moves between compartments to avoid an electric
shock in response to an auditory stimulus . -
pubmed
37 % of
patients had were found to have pathological tortuosity combined with haemodynamically significant ICA
stenosis . -
pubmed
It was demonstrated that surgical management of elderly
patients with pathological tortuosity is an effective method of prevention of
ischaemic stroke . -
pubmed
The complications rate in
patients presenting with combined
atherosclerotic lesions of the ICA and its pathological tortuosity , should adequate surgical policy be employed , falls within the framework of the accepted standards and does not depend on the type of ICA lesion . -
pubmed
Senescent peritoneal mesothelium induces a pro - angiogenic phenotype in
ovarian cancer cells in vitro and in a
mouse xenograft model in vivo . -
pubmed
The same was the case for the vascularization , size and number of
tumors that developed in the
mouse peritoneum upon injection of
ovarian cancer cells with senescent HPMCs . -
pubmed
Signs of
nausea - related behavior were observed in 25 % of the
rats treated with
buprenorphine . -
pubmed
We describe a 16 - year - old
boy with
rhabdomyosarcoma , consistent with embryonal subtype , of the lower extremity who received systemic neoadjuvant chemotherapy and subsequent excision . -
pubmed
Stick injuries in
dogs . -
pubmed
Pulmonary Tuberculosis in Humanized
Mice Infected with
HIV-1 . -
pubmed
Co -
infection with
HIV increases the morbidity and mortality associated with
tuberculosis due to multiple factors including a poorly understood microbial synergy . -
pubmed
We developed a novel small animal model of
co - infection in the humanized
mouse to investigate how
HIV infection disrupts pulmonary containment of
Mtb . -
pubmed
Following dual
infection ,
HIV - infected cells were localized to sites of Mtb - driven
inflammation and mycobacterial replication in the lung . -
pubmed
Consistent with disease in
human subjects , we observed increased mycobacterial burden , loss of
granuloma structure , and increased progression of
TB disease , due to
HIV co - infection . -
pubmed
These results suggest that in the early stages of
acute co - infection in the humanized
mouse ,
infection with
HIV exacerbates the pro - inflammatory response to pulmonary Mtb , leading to poorly formed
granulomas , more severe lung pathology , and increased mycobacterial burden and dissemination . -
pubmed
Despite efforts to fully understand the
Bacillus anthracis toxin components , the gastrointestinal ( GI )
anthrax mechanisms have not been fully elucidated . -
pubmed
In the present study , to identify the profile of the proteins potentially involved in GI
anthrax , protein - protein interactions were investigated using
human stomach T7 phage display ( T7PD ) cDNA libraries . -
pubmed
BACKGROUND :
Patient selection for endovascular revascularization treatment ( ERT ) in
acute ischemic stroke depends on the expected benefit - risk ratio . -
pubmed
METHODS : Consecutive
stroke patients from a single
stroke center with distal internal carotid artery- , proximal middle cerebral artery- or T - occlusions treated with ERT were retrospectively selected . -
pubmed
Three
patients ( 22 % ) had a lateral dural tear with an associated
spinal meningeal diverticulum , and in 1
patient ( 7 % ) , a
dorsal osteophyte was causal . -
pubmed
METHODS : Thirty - four
subjects with mild - to - moderate
COPD were randomly allocated 2:1 to ICS or placebo treatment in a double - blinded clinical trial over 6 months . -
pubmed
BACKGROUND : In the past 3 decades , a better understanding of gene mutations and their role in
carcinogenesis has led to improvement in our ability to treat
patients with
metastatic disease . -
pubmed
METHODS : DNA was collected from 165 randomly selected specimens of
patients who underwent margin - negative resection of
colorectal liver metastases with curative intent . -
pubmed
BACKGROUND :
Pleurostomophora richardsiae ( formerly
Phialophora richardsiae ) is a dematiaceous fungus that is an uncommon cause of
ocular infection . -
pubmed
The
patient was afebrile with
leukocytosis . -
pubmed
The
patient died several weeks after presentation due to a massive
intracranial hemorrhage . -
pubmed
RESULTS : The histology of the
breast tumour in the 58
patients was ductal type in 52 ( 90 % ) , lobular in 4 ( 7 % ) , and
mucinous in 2 ( 3 % ) . -
pubmed
The levels of TBRs were not significantly different between the
patients groups with
tumours of 2 cm or less and greater than 2 cm ( P=0.131 ) . -
pubmed
Perioperative morbidity , oncological outcomes and predictors of pT3a upstaging for
patients undergoing partial nephrectomy for cT1
tumors . -
pubmed
Patients with pT3a had a higher estimated
blood loss , transfusion rate ,
ischemia time and overall complications , though there were no differences in median e - GFR decline and major ( Grade III - V ) complications . -
pubmed
The remaining 39
patients were not examined owing to volume intolerance ,
cow 's milk
intolerance or
allergy , inability to lie still , or parents refusing participation . -
pubmed
GERD recurred in 7 ( 20 % )
patients . -
pubmed
Preoperative T1/2 in the seven
patients with recurrent
GERD was median 45 [ 21 - 87 ] min compared to 44 [ 16 - 121 ] min in the 28
patients without recurrent
GERD ( p=0.92 ) . -
pubmed
Here , we review the literature that has led to our current understanding of B cell regulation of
atherosclerosis , touching on the importance of subsets , local regulation ,
human translation , and therapeutic potential . -
pubmed
High - dose chemotherapy followed by autologous stem cell transplantation ( ASCT ) is frequently performed in
patients with
hematologic malignancies . -
pubmed
Music has been demonstrated to improve
nausea and
pain in
patients undergoing chemotherapy , but little data are available regarding the effects of music therapy in the transplantation setting . -
pubmed
In a prospective study ,
patients with
lymphoma or
multiple myeloma undergoing ASCT were randomized to receive either interactive music therapy with a board - certified music therapist or no music therapy . -
pubmed
Secondary outcomes were narcotic
pain medication use from day -1 to day +5 and impact of ASCT on
patient mood as assessed by Profile of Mood States ( POMS ) on day +5 . -
pubmed
Patients who received MT had slightly increased
nausea by day +7 compared with the no music therapy
patients . -
pubmed
The music therapy and no music therapy
patients had similar
pain scores ; however , the
patients who received music therapy used significantly less narcotic
pain medication ( median , 24 mg versus 73 mg ; P = .038 ) . -
pubmed
Music therapy may be a viable nonpharmacologic method of
pain management for
patients undergoing ASCT ; the music therapy
patients required significantly fewer
morphine equivalent doses compared with the no music therapy
patients . -
pubmed
Magnetic Resonance Diffusion data of 33
patients with
BD , 19 with
SCZ and 35 healthy controls were acquired . -
pubmed
Respiratory syncytial virus in adults with severe
acute respiratory illness in a high
HIV prevalence setting . -
pubmed
We studied the epidemiology of
RSV - associated severe
acute respiratory illness (
SARI ) hospitalizations in adults in South Africa from 2009 through 2013 . -
pubmed
On multivariable analysis , HIV - infected individuals with
RSV - associated
SARI had greater odds of being in the age groups 18 - 44 and 45 - 64 years ( odd ratios ( OR ) 26.3 ; 95 % confidence interval ( CI ) 6.2 - 112.1 and OR 11.4 ; 95 % CI 2.6 - 50.0 ) compared with those & gt;=65 years and being female ( OR 2.7 ; 95 % CI 1.4 - 5.4 ) . -
pubmed
The relative risk of hospitalization with
RSV - associated
SARI was 12 - 18 times higher in HIV infected individual compared to that of
HIV - uninfected . -
pubmed
CONCLUSION : The incidence of
RSV - associated
SARI was higher in HIV - infected individuals and those aged 65 years and older . -
pubmed
Further studies are warranted to describe the disease association of
RSV detected in adults with
SARI . -
pubmed
Nasopharyngeal and oropharyngeal swabs were collected from hospitalized patients meeting SARI case definitions and were analyzed for
infection with influenza ,
respiratory syncytial virus (
RSV ) ,
adenovirus (
AdV ) ,
human metapneumovirus (
hMPV ) and
human parainfluenza virus types 1 - 3 ( hPIV1 - 3 ) . -
pubmed
Participants with
hMPV infections and participants less than five years of age were significantly less likely than participants not infected with
hMPV and those older than five years of age , respectively , to experience a severe outcome , while participants with a pre - existing
chronic disease were at increased risk of a severe outcome , compared to those with no reported pre - existing
chronic disease . -
pubmed
To evaluate their potential anticancer effects on
human carcinoma cells , anti - proliferation , DNA binding and cleavage , and apoptosis elicitation were examined . -
pubmed
METHODS : Two hundred and thirty - five
patients who underwent catheter ablation for paroxysmal
AF ( 119 in irrigated - tip , 51 in contact - force sensing - guided , and 65
patients in second - generation cryoballoon ablation ) were included . -
pubmed
Of the total population , 45
patients had
recurrence . -
pubmed
The aim of the study was to prospectively evaluate the prevalence and progression of
HP in
patients after
TBI and
SAH in Icelandic population . -
pubmed
METHODS AND PROCEDURES : A total of 27
patients were included , 15
patients with
TBI and 12
patients with
SAH . -
pubmed
RESULTS : At three months , 16.7 % ( 2/12 ) of the
patients had
HP after
TBI and 33.3 % ( 4/12 ) after
SAH . -
pubmed
At 12 months , 21.4 % ( 3/14 ) of
patients had
HP after
TBI and 9.1 % ( 1/11 ) after
SAH . -
pubmed
CONCLUSIONS : There is a considerable risk of
HP after
TBI and reason to study pituitary function further in
patients with
SAH . -
pubmed
However , single time - point measurements appear to furnish insufficient information for detecting and predicting
AKI in intensive care unit
patients who are frequently affected by multiple and transient / persistent renal insults . -
pubmed
RESULTS : Among the enrolled 272
patients , 33 were determined to show newly developed
AKI after ICU admission , 58 showed worsening of
AKI , 57 recovered from
AKI , and 38 died in the hospital . -
pubmed
We performed miRNA in situ hybridization , RNA - sequencing , and immunohistochemical analyses of
tumor tissues from 51 untreated
patients with
EAC in the Netherlands . -
pubmed
Clinical and survival data were collected for
patients , and
EAC subtypes were determined . -
pubmed
Resident brain neural precursor cells develop age - dependent loss of therapeutic functions in
Alzheimer 's
mice . -
pubmed
To evaluate brain NPC function in relation to disease pathology , we first characterized the pathological properties of 5xFAD transgenic
mouse model of
Alzheimer ' s disease at different ages . -
pubmed
We found that age 7 months is a critical time point of heavy
amyloid deposition and
gliosis but before neurodegeneration and a normal basal rate of NPC turnover in the subventricular zone ( SVZ ) of 5xFAD
mice as compared to wild - type
mice . -
pubmed
Importantly , these functions were fully preserved in 2 - month - old 5xFAD
mice , a time point before
Alzheimer ' s disease - specific pathological changes . -
pubmed
The dysfunctional properties and downregulation of gene expression were reversible in NPCs derived from 7 - month - old 5xFAD
mice following in vitro expansion and were reproduced in wild - type
NPC by addition of amyloid beta peptide . -
pubmed
In 218 consecutive symptomatic
patients undergoing who underwent ablation for
AF ( 143 paroxysmal
AF ; 78 persistent
AF ) , the EATV index ( EATVI : EATV / body surface area , mL / m2 ) was measured using 320 - row multidetector computed tomography . -
pubmed
METHODS : Three - dimensional multiple b - value 3 He and 129
Xe diffusion - weighted MRI was acquired with compressed sensing at 1.5 T from 51 and 31 subjects , respectively , including healthy volunteers , ex - smokers ,
idiopathic pulmonary fibrosis , and
chronic obstructive pulmonary disease patients . -
pubmed
BACKGROUND :
Anterior cruciate ligament ( ACL ) rupture is a serious
injury in
patients who are typically young and athletically active , with potential long - term complica- tions including functional limitation , posttraumatic
osteoarthritis of the knee , and impaired quality of life . -
pubmed
BACKGROUND : Besides the numerous biologic and pharmacologic functions in the
human body that act as potent antioxidants ,
flavonoids (
flavones ,
flavanones ,
flavonols ,
flavanols and
isoflavones ) are noted as
cancer preventive or therapeutic agents . -
pubmed
Dyslexic children are sluggish in disengaging spatial attention . -
pubmed
The present study examined the time course of attentional orienting in
dyslexic and typically developing
children , by parametrically manipulating the cue - target onset asynchronies in a spatial cueing task . -
pubmed
Experiment 1 revealed an early facilitation effect in
dyslexic children , suggesting that they have no issue in engaging attention to salient spatial locations . -
pubmed
When a second cue was presented to encourage attentional disengagement in Experiment 2 , reliable IOR effects were observed in the same group of
dyslexic children , and importantly , the onset time of IOR was comparable with that in healthy controls . -
pubmed
These results clearly show a selective impairment of attentional disengagement in
dyslexic children and provide a solid empirical basis for intervention programmes focusing on attentional shifting . -
pubmed
The in vivo anti -
melanoma effects of HANPs were studied in the
tumor model of
nude mice . -
pubmed
This study was designed to explore the currently understudied alternative mechanisms by which compound
alpha - ketoacid tablets ( KA ) influenced
ischemia - reperfusion ( IR ) induced
murine renal injury , and to probe the current status of KA administration on staving
CKD progression in Chinese
CKD patients at different stages . -
pubmed
METHODS : In
animal experiment , IR surgery was performed to mimic progressive
chronic kidney injury , while KA was administrated orally . -
pubmed
In clinical research , after adjusting basic demographic factors ,
patients at stages 4 and 5 in KA group presented a much delayed and slower incidence of
eGFR decrease compared to those in No - KA group ( hazard ratio ( HR ) = 0.115 , 95 % confidence interval ( CI ) 0.021 - 0.639 , p = 0.0134 ) , demonstrating a positive effect of KA on staving
CKD progression . -
pubmed
BACKGROUND : Documentation of disease activity in
patients affected by
Crohn ' s disease (
CD ) is mandatory in order to manage
patients properly . -
pubmed
CONCLUSION : LP on contrast - enhanced MRI is a specific finding to rule out active
inflammation in
patients with
CD . -
pubmed
We analyzed 225 fixed
HCC tissues ( from 2 cohorts ) from
patients in China by immunohistochemistry and obtained survival data . -
pubmed
Human umbilical cord vein endothelial cells were exposed to sera from healthy donors ( n = 20 ) and
patients with
end - stage renal disease on haemodialysis ( n = 20 ) . -
pubmed
Dilatation of Retinal Arterioles Induced by Topical
Dorzolamide for One Week Is Impaired in
Patients with
Type 1 Diabetes and
Mild Retinopathy . -
pubmed
However , the effect of sustained treatment with
CAI on retinal arterioles in normal
persons and in
patients with
diabetic retinopathy is unknown . -
pubmed
RESULTS : Treatment with
dorzolamide for 1 week significantly increased the diameter of retinal arterioles in normal
persons , and breathing in of a
hypercapnic gas mixture reduced this response . -
pubmed
The pathological vasodilatation and reduced retinal autoregulation in
patients with
diabetic retinopathy were unaffected by
dorzolamide and
hypercapnia . -
pubmed
Releasing Wolbachia - infected
Aedes aegypti to prevent the spread of
dengue virus : A mathematical study . -
pubmed
Wolbachia is a bacterium that is present in 60 % of insects but it is not generally found in
Aedes aegypti , the primary vector responsible for the transmission of
dengue virus ,
Zika virus , and other
human diseases caused by RNA viruses . -
pubmed
For
AS patients , NSAID monotherapy increased the probability of
hematuria 2.4 - fold and the probability of mixed manifestations of
renal involvement 3.0 - fold . -
pubmed
CONCLUSION : NSAID or csDMARD monotherapy may significantly increase renal involvement in Chinese
AS patients . -
pubmed
Methacholine challenge has proved to be a highly sensitive test to diagnose
asthma in
patients with chronic respiratory symptoms and preserved baseline lung function ( FEV1 > 70 % pred . ) -
pubmed
We conducted a retrospective study on 270
patients recruited from the University
Asthma Clinic of Liege . -
pubmed
Controlling some metabolic variables will decrease the prevalence of these disorders and improves clinical remedy and quality of life in
patients with
type 2 diabetes . -
pubmed
METHODS :
Women > = 50 years of age with low - risk invasive
breast carcinoma ( pT1 - 2 pN0 ) were randomly assigned to 50 Gy/25 fr ( 5 weeks ) or 30 or 28.5 Gy in 5 fr of 6.0 or 5.7 Gy ( 1 week ) . -
pubmed
This study assessed the temporal pattern of
neuronal loss in subacute
ischemic stroke patients using
1H magnetic resonance spectroscopy , in parallel with functional recovery at 2 , 6 and 12 weeks after
stroke . -
pubmed
HPV - positive
HNSCC cell lines show strongly enhanced radiosensitivity after photon but not after
carbon ion irradiation . -
pubmed
METHODS AND RESULTS : Prescription data for 450 518
patients with
AF from 3352 General Practices in England , was obtained from the GRASP - AF registry , 2009 - 2018 . -
pubmed
We apply this strategy to an ex vivo
bovine model of discectomy and demonstrate that
PEGDA molecular weight tunes hydrogel mechanical properties and affects
herniation risk , where IVDs repaired with low - modulus hydrogels composed of 20kDa
PEGDA failed at levels at or exceeding discectomy , the clinical standard of care . -
pubmed
METHODS : This retrospective study included 43
patients diagnosed with
BP . -
pubmed
CONCLUSION : Although entrapment of FN in the labyrinthine segment in BP was known , this study showed that the cisternal FN , which could be evaluated more conveniently , enlarged in the paralytic side compared to the normal side , and revealed the necessity of performing the comparison among the MRI studies on
BP patients by using a standardized measurement method . -
pubmed
The emergence outbreak caused by a novel
severe acute respiratory syndrome coronavirus 2 (
SARS - CoV-2 ) has received significant attention on the global risks . -
pubmed
Neurosurgical consultation should be considered in pediatric
patients with
cerebellitis . -
pubmed
Human intact tibiae were tested using the static bending method to learn about the relationship between the
fracture surface and the failure mode . -
pubmed
Zinc metabolism and
dibutyl phthalate - induced
testicular atrophy in the
rat . -
pubmed
Clinical features and results of nerve conduction and electromyographic investigations were studied in 13 consecutive
patients with
idiopathic ischemic necrosis of the femoral head . -
pubmed
Of these
patients , one was a
diabetic , one had received
steroids and six gave a history of high
alcohol intake . -
pubmed
Skeletal muscles of newborn albino
mice experimentally infected with the virus showed degeneration ,
atrophy ,
necrosis , and inflammatory changes of muscle fibers . -
pubmed
Antibody prevalence in
humans and animals ranged from 10.3 % by neutralization tests of samples from healthy people in 1979 to 26.4 % by CF tests of samples from people with
febrile illnesses in 1982 . -
pubmed
The high prevalence of antibody in
pigs ,
horses , and
goats ( 17.6 % to 37.5 % ) indicated that
infection with Getah or a closely related virus is relatively common in domestic animals . -
pubmed
Clinical signs were confined to the lower limbs in 3
patients ; the remaining
patient presented only
paraesthesiae in 4 limbs . -
pubmed
Hemodynamic effects of
ibopamine on the pulmonary circulation and right ventricular performance in
patients with
chronic obstructive pulmonary disease . -
pubmed
We have studied the effects of
ibopamine , an oral
dopamine derivative , on pulmonary hemodynamics and blood gas values when given as a single oral dose ( 100 mg ) to
patients with severe hypoxic
chronic obstructive pulmonary disease . -
pubmed
These results do not indicate a role for
ibopamine in the treatment of
patients with hypoxic
chronic obstructive pulmonary disease and
pulmonary hypertension , but , in addition , do not indicate any major deleterious effects of
ibopamine on pulmonary hemodynamics or blood gas values in such
patients . -
pubmed
[ Sputum penetration of
levofloxacin and its clinical efficacy in
patients with
chronic lower respiratory tract infections ] . -
pubmed
The clinical efficacy and the safety of
LVFX were also evaluated in a total of 13
patients with
respiratory tract infections associated with
bronchiectasis ,
diffuse panbronchiolitis , etc . -
pubmed
All the 3
strains of
Haemophilus influenzae were eradicated . -
pubmed
Of the 3
strains of
Pseudomonas aeruginosa , eradication , decrease , and unchange was observed for 1
strain each . -
pubmed
One
strain of
Streptococcus pneumoniae remained unchanged . -
pubmed
Charts of 90
patients consecutively operated during 6 years for acute perforated
ulcer were analysed . -
pubmed
[ Spontaneous
rupture of the abdominal wall in cirrhotic
patients with
ascites ] . -
pubmed
Micromolar concentrations of
diethyldithiocarbamic acid (
DDC ) kill
fungi ,
bacteria and
malaria . -
pubmed
coli spheroplasts , suggesting a possible common mechanism of hemolytic and microbicidal action ; ( 2 ) higher ratios of drug : metal ( greater than 4:1 ) diminished hemolytic and , as observed earlier , microbicidal effects ; ( 3 )
cobalt , known to suppress the microbicidal effects of
DDC :
Cu , also prevented red cell lysis ; ( 4 ) despite the necessary involvement of
copper in
DDC - mediated
hemolysis , there was no evidence of oxidative damage to erythrocytes , and both lysis of erythrocytes and killing of
E. - pubmed
In contrast to adult
mice , young A / J
mice , developed an acute
hepatitis following
infection with Mouse Hepatitis virus type 3 . -
pubmed
Studies of chemically induced cell
injury and
death , which have used as model systems freshly isolated
rat hepatocytes and hepatocytes in culture , are discussed . -
pubmed
Homogeneous distribution and pressure dependent reduction of coronary blood flow in right ventricular free wall during
coronary hypoperfusion in anaesthetised open chest
dogs . -
pubmed
Chronic hypervitaminosis A in
adults is a clinical
syndrome that can develop over varying periods of time depending on the average daily intake of
vitamin A. -
pubmed
Hepatic cirrhosis developed as a manifestation of
vitamin A toxicity in one of the
patients ; this appears to be the first reported case of
chronic hypervitaminosis A in an adult induced by the long - term frequent ingestion of
beef liver . -
pubmed
Ten
patients have been studied using the Doppler flowmeter and phlebography to compare
varicoceles and
varicose veins in the legs and to decide whether or not the same principles apply in their surgical treatment . -
pubmed
Gonadoblastoma arising from the streak gonad was noted in five of the six
patients . " -
pubmed
We recommend evaluation of the gonads in prepubertal
girls with
end - stage renal disease at risk for this
syndrome . -
pubmed
Escherichia coli strain N100 has been mutagenized by transposon mutagenesis and mutants with a cell surface leaky phenotype have been isolated . -
pubmed
Partial splenic embolization in
patients with
thalassemia major . -
pubmed
The sample consisted of lateral roentgenographic cephalograms from 41
children who had been treated with functional appliances for
anterior crossbites and from their respective parents . -
pubmed
The radiosensitizing and toxic effects of
RSU-1069 on hypoxic cells in a
murine tumor . -
pubmed
Our studies have been carried out using the
SCCVII squamous carcinoma implanted subcutaneously in
C3H mice , using a technique we recently developed which facilitates isolation of
tumor cell subpopulations from known locations relative to the
tumor blood supply . -
pubmed
The results obtained to date clearly demonstrate that
RSU-1069 is an efficient
hypoxic cell radiosensitizer and cytotoxin in this
murine tumor and has little effect on well perfused ( i.e. -
pubmed
Combined
chlorambucil and
prednisolone treatment of five
patients with
Wegener ' s granulomatosis . -
pubmed
A modified method of culturing
human amniotic fluid cells for prenatal detection of
genetic disorders . -
pubmed
Incidence of
Linguatula serrata infection in Cairo mongrel
dogs . -
pubmed
Epidemiology of chronic
congenital and perinatal infections of
man . -
pubmed
Use of an electroimmunodiffusion method on cellulose acetate films for the detection of antigenicity in
human breast cancers that is related to the major core antigen of
mouse mammary
tumor virus (
MuMTV ) . -
pubmed
Eikenella corrodens in
hand infections . -
pubmed
Clinical and therapeutic information on 21 patients with
hand infection due to
Eikenella corrodens is reported . -
pubmed
A male
patient , aged 7.5 years , with known
sickle cell trait , presented for correction of
Fallot 's tetralogy . -
pubmed
A 37 - year - old
man with an evolving
anterior myocardial infarction received intracoronary thrombolytic therapy six hours after its onset . -
pubmed
Two
patients died of recurrent
carcinoma at 1 and 2 3/4 years respectively . -
pubmed
Three
infants with
malonic aciduria are reported , one of whom could be studied in detail . -
pubmed
All
children had severe and progressive
encephalopathy with intermittent
ketoacidosis and
hypoglycemia . -
pubmed
Biochemical studies revealed that one
patient had neither
malonyl - CoA decarboxylase nor glutaryl - CoA dehydrogenase deficiencies . -
pubmed
This variant of
malonic aciduria is different from that of four
patients previously reported , both in its clinical and biochemical presentations . -
pubmed
Biopsies of rectus abdominus muscle were taken from eight
obese and eight control
subjects undergoing elective surgery (
body mass index 52.9 + /- 3.6 vs 25.7 + /- 0.9 ) . -
pubmed
Infection of
cattle with
bluetongue viruses in Queensland , Australia : results of a sentinel herd study , 1990 - 1992 . -
pubmed
Between 1990 and 1992 , 47 sentinel herds of 10 - 20
cattle each were established throughout Queensland , Australia to monitor
bluetongue virus infection . -
pubmed
Only seroconversions to
bluetongue virus serotypes 1 and/or 21 were detected in the study ; no evidence was found of
infection with other serotyped previously isolated in Australia ( 3 , 9 , 15 , 16 , 20 , 23 ) . -
pubmed
This study confirmed the presence of only serotypes 1 and 21 in Queensland and demonstrated the sporadic and restricted nature of
bluetongue virus infection in the Queensland
cattle herd . -
pubmed
An ELISA test for the serological diagnosis of
amoebic liver abscess (
ALA ) was standardized and evaluated in sera from three groups of patients : ( 1 ) three
patients with diagnosis confirmed by isolation of the parasite , ( 2 ) thirty seven
patients with diagnosis established by clinical findings and ultrasound studies and ( 3 ) seven patients whose diagnosis were established by clinical findings and a positive double immunodifusion test . -
pubmed
Ninety one serum samples from healthy subjects and 22 from
patients with other
liver or parasitic diseases were also included in the study . -
pubmed
Multivariate analyses between conditioned taste aversion ( CTA ) and radial maze acquisition ( RMA ) scores and percentages of neuronal dropout within thalamic and telencephalic structures were completed for
rats in which overt
seizures had been evoked following a single systemic injection of
lithium /
pilocarpine . -
pubmed
DESIGN AND METHODS : One hundred and four
patients with
essential hypertension were classified as salt - sensitive or non - salt - sensitive depending on their blood pressure response to salt restriction . -
pubmed
Gunshot wounds to the brain in
children and adolescents : age and neurobehavioral development . -
pubmed
Neurobehavioral outcome after
craniocerebral gunshot wounds was evaluated in a prospective , 3 - year , longitudinal follow - up of a consecutive case series of 13
children and adolescents . -
pubmed
At the time of follow - up , younger
children sustaining
gunshot wounds had slightly lower intelligence quotient scores and similar receptive language , expressive language , and gross motor scores compared with children with severe
closed - head injury . -
pubmed
OBJECTIVE : To evaluate the clinical significance of DNA ploidy pattern for
patients with
nonseminomatous germ cell testicular tumors who did not receive
platinum - based chemotherapy . -
pubmed
We obtained longitudinal assessments of plasma measures of
dopamine (
pDA ) ,
norepinephrine (
pNE ) , and their metabolites ,
homovanillic acid (
pHVA ) and
3 - methoxy-4 - hydroxyphenylglycol (
pMHPG ) , in eight treatment - resistant or treatment - intolerant
schizophrenic patients who were treated with
clozapine for 12 weeks following a prolonged drug - washout period . -
pubmed
Sixty - two
patients with
port wine stains completed a questionnaire related to their flashlamp - pumped pulsed tunable dye laser treatment . -
pubmed
A 35 - year old
woman with
myoma of the uterus was admitted with an
acute abdomen and
ileus on the 16th day after delivery . -
pubmed
Magnetic resonance images and audiologic data on 22
patients with
NF2 who underwent multiple studies at the National Institutes of Health between 1983 and 1993 were reviewed to determine the growth characteristics of
ANs in these
patients . -
pubmed
We reviewed the clinical characteristics , response to therapy , and long - term prognosis in 13
children ( 1.5 to 16 years of age ) diagnosed with
CIDP at Washington University Medical Center , St. Louis , and the Royal Children 's Hospital , Melbourne , Australia , between 1979 and 1994 . -
pubmed
Preceding events within 1 months of onset , mostly intercurrent
infections or vaccinations , occurred in seven
children ( 54 % ) . -
pubmed
Ten
children ( 77 % ) had residual
weakness after an average follow - up of 6 years . -
pubmed
There seems to be two populations of
children with
CIDP . -
pubmed
One subgroup , with a favorable prognosis , progressed to peak disability over less than 3 months ; these
children often have a monophasic course with complete resolution of
symptoms and signs and withdrawal from all medications by 1 year after onset . -
pubmed
A second subgroup progressed for 3 months or longer ; these
children all required substantial does of
prednisone for prolonged periods and had considerable long - term morbidity with persistent
weakness . -
pubmed
Cell proliferation and ploidy of
human solid tumours : methodological experience with in vivo
bromodeoxyuridine and DNA flow cytometry . -
pubmed
The overall feasibility , together with some critical aspects of the DNA /
bromodeoxyuridine (
BrdU ) in vivo assay for cell kinetic studies in
human solid tumours , are reported , based on our experience in recent years . -
pubmed
These findings have implications on the applicability of peptide vaccination with peptide MT(27 - 35 ) on
melanoma patients . -
pubmed
Overall , there was little support for the prediction of a difference in acute outcome between
patients with or without pretreatment
cognitive dysfunction and negative stressors . -
pubmed
significantly suppressed neovascularization induced by
M5076 mouse tumor cells in a
mouse dorsal air sac assay system , compared to the vehicle alone ( P & lt ; 0.05 ) . -
pubmed
Epithelial tumors , common in the adult , are uncommon in
children and are of mild to moderate malignant potential . -
pubmed
PATIENTS AND METHODS : Between May 1991 and December 1996 146
patients with
biliary pancreatitis were subjected to ERCP after laboratory tests and ultrasound screening of the biliary system . -
pubmed
RESULTS : Of the 70
patients with attempted LC 26 had common
bile duct calculi , 23 had an impacted papillary stone and 10 had signs of a stone passage . -
pubmed
However , the relative antioxidant potencies of
CGP 2881 and
probucol seen with oral administration to
hypercholesterolemic rabbits were reversed when the compounds were given intravenously . -
pubmed
In addition , the effects of these antioxidants were potentiated when given to normocholesterolemic
rabbits compared to
hypercholesterolemic animals . -
pubmed
[ Epidemiological observations on the first case of
human paragonimiasis and potential intermediate hosts of Paragonimus sp . -
pubmed
Further , by various enzymatic treatments of
BTV - permissive L929 cells , preliminary data have been obtained which indicated that the
BTV receptor molecule(s ) is likely to be a glycoprotein and that either the protein moiety of the glycoprotein or a second protein molecule could also serve as a coreceptor for
BTV infection . -
pubmed
Anxiety in
mice following acute
aspartame and
ethanol exposure . -
pubmed
The results showed that rate of
MP infection in
COPD patients was 34.59 % . -
pubmed
We discuss the pathophysiological mechanism for the induction of this rare form of
thyrotoxic cardiomyopathy and emphasize that awareness of this possible presentation of
hyperthyroidism is essential to identify
patients with potentially reversible
dilated cardiomyopathy . -
pubmed
By virtue of their anatomic location in the eye , capsular - supported or sutured PCIOLs are appropriate for
patients with
glaucoma ,
diabetes , cornea guttata or low endothelial cell count , peripheral
anterior synechiae , or known or suspected
cystoid macular edema . -
pubmed
They may also be appropriate when the
patient with
aphakia is young and has a relatively long life expectancy . -
pubmed
Obesity modifies the relationship between ambulatory blood pressure and natriuresis in
children . -
pubmed
RESULTS : Weight and
sodium excretion are directly associated with
systolic blood pressure ; however , the relationship between blood pressure and
sodium excretion seems to be modified in
obese children as compared to controls . -
pubmed
The interaction between
sodium excretion and weight was negative indicating that the rate of change of
systolic blood pressure by
sodium unit is smaller for the
obese than for the non - obese , even though at the same urinary
sodium excretion level the
obese children had higher ambulatory
systolic blood pressure . -
pubmed
Suppression of
androgen action and the induction of gross
abnormalities of the reproductive tract in
male rats treated neonatally with
diethylstilbestrol . -
pubmed
This study evaluated whether
androgen action is altered in
rats treated neonatally with
diethylstilbestrol (
DES ) at a dose that induced
reproductive tract abnormalities . -
pubmed
To test whether suppression of
androgen production or action alone could induce comparable
reproductive abnormalities to 10 microg
DES ,
rats were treated neonatally with either a potent
gonadotropin - releasing hormone antagonist (
GnRHa ) or with
flutamide ( 50 mg / kg / day ) . -
pubmed
Monocyte / macrophage activation by normal
bacteria and
bacterial products : implications for altered epithelial function in
Crohn ' s disease . -
pubmed
Intestinal immune cells are less reactive than those in the peripheral blood ; however , such cells from patients with
Crohn ' s disease may be more responsive to
bacterial products . -
pubmed
Lamina propria mononuclear cells ( LPMCs ) and peripheral blood monocytes ( PBMs ) were obtained from
patients with
Crohn ' s disease and control patients . -
pubmed
LPS - activated PBMs from both controls and
patients with
Crohn ' s disease significantly increased Isc ( approximately 300 % ) and reduced transepithelial electrical resistance ( approximately 40 % ) . -
pubmed
PATIENTS AND METHODS : Twenty - five
patients with nonresectable
NSCLC were enrolled in an open - label , multicenter phase II study of three cycles of regimen A ,
carboplatin ( area under the curve , 6 ; day 1 ) plus
paclitaxel ( 175 mg / m(2 ) , day 1 ) , or regimen B ,
cisplatin ( 100 mg / m(2 ) , day 1 ) plus
vinorelbine ( 25 mg / m(2 ) , days 1 , 8 , 15 , and 22 ) in combination with intratumoral injection of 7.5 x 10(12 ) particles of
SCH 58500 ( rAd / p53 , day 1 ) . -
pubmed
Transgene expression was confirmed in
tumor samples from 68 % of
patients , and toxicities attributable to gene therapy were mild to moderate . -
pubmed
Intussusception at the ileocaecocolic junction in
kittens . -
pubmed
This finding confirms our earlier observation that
melatonin exerts a pro - apoptotic effect on
murine colonic cancer cells . -
pubmed
Failure of resting echocardiography and cardiac catheterization to identify
pulmonary hypertension in two
patients with
type I Gaucher disease . -
pubmed
Screening with echocardiography is recommended for
Gaucher patients . -
pubmed
Two
patients naive to enzyme replacement therapy are presented in whom resting echocardiography revealed no evidence of
PHT . -
pubmed
The diagnosis of
PHT was made with open lung biopsy in one
patient and
dobutamine echocardiography in the other . -
pubmed
Resting echocardiographic assessment may fail to identify
PHT in
patients with
Gaucher disease . -
pubmed
A
scar was selected for treatment in each
patient and divided into four equal 2 cm segments . -
pubmed
The 532 nm Q - switched
Nd : YAG laser may be preferred by
patients particularly distressed by the dark color of their
scars . -
pubmed
This has been shown in different
mammalian species under experimental conditions of acute or chronic
hypoxemia . -
pubmed
In the present study in
rats , we compared the effects of acute and chronic
hypoxemia on the activity of afferents from the tibialis anterior muscle to investigate the existence of possible adaptive mechanisms to
hypoxaemia . -
pubmed
Chronic
hypoxaemia was achieved by exposing the
rats for 45 consecutive days to a gas mixture containing 10 %
oxygen in
nitrogen , whereas acute
hypoxaemia was limited to a 1 - h exposure to a 10 %
oxygen mixture . -
pubmed
This may explain the observation that sensorimotor control of skeletal muscles is often markedly impaired in
hypoxemic humans . -
pubmed
OBJECTIVE : To assess effect of
Tanshinone II A on the apoptosis of
human nasopharyngeal carcinoma ( NPC ) cell line
CNE-1 and inquire into the mechanism there in involved . -
pubmed
A
girl with
rickets and
nephrocalcinosis . -
pubmed
This
patient is an example of
hypercalciuric rickets , most likely due to an
inherited disorder of phosphate metabolism . -
pubmed
Use of highly active chemotherapy in
patients with unresectable
disease ( particularly
liver metastases ) achieves responses that allow a subset of
patients to proceed to potentially curative surgery . -
pubmed
The emergence of novel agents targeted at processes such as
tumor angiogenesis will complement cytotoxic chemotherapy , while improved understanding of
tumor biology should enable agents to be selected according to the likely sensitivity of the
disease in a particular
patient . -
pubmed
[ Spores of
tree lichin ,
Palmeria caperata L , as cause of
allergic skin disease ] . -
pubmed
[ Research on
phenolsteroid metabolism ; chromatographic analysis of
phenolsteroid metabolites in
women with
fibroleiomyoma of the uterus ] . -
pubmed
L-3 , 4 - Dihydroxyphenylalanine (
L - dopa ) has been widely used for the treatment of
Parkinson ' s disease (
PD ) , but its pharmacokinetics in the striatum have hardly been investigated , especially in
primates . -
pubmed
MATERIALS AND METHODS : A total of 14
oncocytomas from 12
patients were collected in 2(1/2 ) years . -
pubmed
A total of 6
tumors from 5
individuals ( 46.2 % ) had
chromosome 1 abnormalities . -
pubmed
Structural anomalies resulting in loss of the short arm of chromosome 1 were found in an additional 2
patients . -
pubmed
Comorbid
depression and platelet
serotonin in hemodialysis
patients . -
pubmed
METHODS : Comorbid
depression and different clusters of
depressive symptoms were assessed in 79 male
HD patients and 35 male
depressed psychiatric
patients . -
pubmed
RESULTS : Comorbid
depression occurred in 50 out of 79
HD patients . -
pubmed
Depressed psychiatric
patients and depressed
HD patients had higher scores of
anxiety , retardation , and
cognitive symptoms than nondepressed
HD patients . -
pubmed
Platelet 5 - HT concentration was lower in depressed or nondepressed
HD patients than in healthy controls , or in depressed
patients . -
pubmed
Among
HD patients , anxious
HD patients had a higher platelet
5 - HT concentration than
HD patients without
anxiety symptoms . -
pubmed
CONCLUSIONS : Comorbid
depression occurred in 63 % of
HD patients . -
pubmed
Dialyzed
patients had decreased platelet
5 - HT concentration , regardless of the occurrence of comorbid
depression . -
pubmed
Higher platelet
5 - HT concentration was related to
anxiety symptoms in
HD patients . -
pubmed
Our data suggest that platelet
5 - HT concentration might be a suitable marker for
anxiety symptoms in dialyzed
patients . -
pubmed
BACKGROUND : The
Wistar Hannover rat has been considered as an alternative
animal model to the
Sprague - Dawley rat in the safety evaluation of candidate pharmaceuticals for potential reproductive and
developmental toxicity . -
pubmed
CONCLUSION : Differences in hematology and chemistry values in pregnant
Wistar Hannover rats are similar to those in
Sprague - Dawley rats and support use of the Wistar Hannover
rat as an
animal model in the assessment of
maternal toxicity . -
pubmed
OBJECTIVE(S ): Aim of the study was to assess the effectiveness and the complications associated with the use of tension - free vaginal tape ( TVT ) in
women with
stress urinary incontinence and low urethral closure pressure ( LUCP ) . -
pubmed
STUDY DESIGN : Thirty - seven
patients with
stress urinary incontinence and LUCP who were treated with the TVT procedure have been included in the study . -
pubmed
CONCLUSION(S ): Our study indicates that the TVT procedure is an effective and well - accepted minimal invasive surgery for treatment of
urinary stress incontinence in
women with LUCP . -
pubmed
The repeated activation of a microelectromechanical systems ( MEMS ) drug delivery device was studied in vivo in
rats to examine the effect of implantation on the device operation and the effect of electrochemical activation on the inflammatory and
wound - healing response . -
pubmed
Cysticercosis and
echinococcosis cause illness and productivity losses in
human and agricultural animal populations . -
pubmed
To evaluate the burden , the monetary and non - monetary impacts of these
zoonoses on
human health , agriculture and society must be considered comprehensively . -
pubmed
Mortality risk factors and validation of severity scoring systems in
critically ill patients with
acute renal failure . -
pubmed
BACKGROUND : Risk stratification and prediction of outcome in
acute renal failure patients in the intensive care unit are important determinants for improvement of
patient care and design of clinical trials . -
pubmed
METHODS : In order to identify mortality risks factors and validate general and specific predictive models for
acute renal failure (
ARF ) patients in the intensive care unit ( ICU ) , 324
patients were prospectively evaluated . -
pubmed
After delivery failed to correct her condition , a liver biopsy revealed
HSV hepatitis . -
pubmed
CONCLUSION : Pregnant
women are susceptible to disseminated
HSV causing
hepatitis . -
pubmed
Management of
JSLE has to challenge three objectives : controlling
disease progression , obtaining
patient 's adherence to treatment , and preventing consequences of medication side effects on growth , puberty , development and fertility . -
pubmed
BACKGROUND : Gastric electrical stimulation ( GES ) , which has been reported to have therapeutic potentials for
gastroparesis and
obesity , involves the surgical placement of electrodes with the
patient under general anesthesia . -
pubmed
Lipoproteins obtained from
anorexia nervosa patients induce higher oxidative stress in
U373MG astrocytes through
nitric oxide production . -
pubmed
BACKGROUND : The outcomes of
patients with localized or locally advanced
prostate cancer treated with external - beam radiotherapy are not well known in Japan . -
pubmed
METHODS : Thirty - four institutions combined data on 679
patients with localized or locally advanced
prostate cancer treated with a total dose & gt;/=60 Gy between 1995 and 2002 . -
pubmed
RESULTS : With a median follow - up of 46 months , the 5 - year overall , clinical progression - free , and biochemical
relapse - free survival rate were 93.0 , 95.3 and 71.9 % for all
patients , respectively . -
pubmed
Two developed
Epstein - Barr virus (
EBV)-associated
diffuse large B - cell lymphomas (
DLBCL ) that were clonally unrelated to the
CLL . -
pubmed
METHODS : A retrospective review was conducted of 236 consecutive
patients who underwent anatomic lung resection for
nontuberculous mycobacteria disease at our institution as part of a multimodality treatment program . -
pubmed
Cerebral perfusion ( HMPAO - SPECT ) in
patients with
depression with
cognitive impairment versus those with
mild cognitive impairment and
dementia of
Alzheimer 's type : a semiquantitative and automated evaluation . -
pubmed
PURPOSE : Comparative evaluation of regional brain perfusion measured by
HMPAO - SPECT of
patients with
mild cognitive impairment (
MCI ) ,
dementia of Alzheimer 's type (
DAT ) and
depression with
cognitive impairment (
DCI ) . -
pubmed
METHODS : A total of 736
patients were investigated because of suspected
cognitive dysfunction . -
pubmed
After exclusion of
patients with other forms of
dementia than DAT or relevant accompanying disorders , SPECT data from 149
MCI , 131 DAT and 127
DCI patients , and 123 controls without any
cognitive impairment , were analysed . -
pubmed
Compared to controls
DCI patients showed
hypoperfusion of the thalamus , lentiform nucleus and medial temporal cortex . -
pubmed
MCI patients differed significantly from controls concerning perfusion in both hemispheric temporal and parietal areas , and in the ( right hemispheric ) posterior part of the cingulate gyrus . -
pubmed
MCI and
DCI patients differed in the parietal , temporal superior and right hemispheric cingulate gyrus posterior cortices . -
pubmed
Global forebrain and regional perfusion was more extensively reduced in DAT
patients and discriminated them from controls , and
MCI and
DCI patients . -
pubmed
CONCLUSION : Automated analysis of
HMPAO - SPECT data from
MCI patients showed significant perfusion deficits in regions also involved in DAT
patients , but ROC analysis demonstrated only moderate sensitivity and specificity for differentiating
DAT patients from controls and
DCI patients . -
pubmed
Finally , the results in
DCI patients again raise the question of
depression as an early symptom of neurodegeneration . -
pubmed
SUBJECTS AND METHODS : The study group consisted of 80
OLP patients and 80 healthy
individuals . -
pubmed
Other factors , related to the etiopathogenesis of
Parkinson ' s disease or to
patients ' endophenotypes , are beginning to be identified . -
pubmed
Gastropericardial fistula and
Candida albicans pericarditis : a rare complication of
gastric adenocarcinoma treated with radiation and chemotherapy . -
pubmed
We report a 47 - year - old
man with gastric
adenocarcinoma who had completed radiotherapy and was on scheduled chemotherapy , who presented with
fever and
chest pain . -
pubmed
Gastric
adenocarcinoma complicated with
gastropericardial fistula and
Candida albicans pericarditis were diagnosed and treated successfully with conservative management . -
pubmed
This case demonstrates that first , panendoscopy may be safely performed in
patients with
gastropericardial fistula without significant risk of
cardiac tamponade ; second , although early diagnosis of
gastropericardial fistula is generally important , delayed recognition may not lead to devastating outcomes even in the absence of surgical intervention . -
pubmed
Episodic vomiting and
headache in
children : consider
occipital epilepsy . -
pubmed
Children with
occipital seizures often have ictal autonomic symptoms such as
pallor and
vomiting and lack motor manifestations . -
pubmed
This has lead to misdiagnosis of
occipital seizures in
children . -
pubmed
The following case report highlights the clinical features of a
child with
occipital epilepsy misdiagnosed as having
migraine . -
pubmed
BACKGROUND : The potential for transmission of
Mycobacterium tuberculosis during air travel has garnered considerable attention in the media and among public health authorities due to high - profile cases of international travelers with
infectious tuberculosis (
TB ) . -
pubmed
Herein , we report the cases of 2
patients who had malignant
ventricular arrhythmias secondary to
ischemic heart disease . -
pubmed
Acute
inflammation was induced in
mice and intestines were analyzed by biochemical and histologic methods . -
pubmed
In vitro
cytotoxicity of the
chlorinated naphthoquinone dichlone to
human endothelial
ECV304 cells . -
pubmed
The sensitivity of these cells to
dichlone was intermediate between that of
human hepatoblastoma HepG2 cells ( least sensitive ) and that of
human GMO5757 fibroblasts . -
pubmed
The later class of compounds reduces remarkably plasma
triglycerides , total
cholesterol and LDL -
cholesterol in
hyperlipidemic rats . -
pubmed
The medical records of 237
patients with invasive
breast cancer who underwent surgery between 1995 and 2006 were reviewed . -
pubmed
These cases included 10
patients ( 4.2 % ) with
mucinous carcinoma . -
pubmed
The
tumor size was T1 in 5
patients and T2 in 5
patients . -
pubmed
Treatment of disfiguring chronic
graft versus host disease in a
child with topical
pimecrolimus . -
pubmed
Even though
Mycobacterium tuberculosis (
Mtb ) remains one of the top microbial killers , more than 90 % of the 2 billion infected individuals never develop active
tuberculosis (
TB ) , indicating efficient immune control of
infection in these individuals . -
pubmed
An important preliminary step in the diagnosis of
leukemia is the visual examination of the
patient 's peripheral blood smear under the microscope . -
pubmed
For over ten years , chemotherapy with
gemcitabine has been standard treatment for those
patients with advanced
pancreatic cancer , prolonging survival by only 5 - 6 months . -
pubmed
Over the past several years , a number of phase II and phase III trials have combined
gemcitabine with these novel treatments , with the hope of prolonging survival in
patients with
pancreatic cancer . -
pubmed
MATERIAL AND METHODS : The survival rates of
testicular cancer patients were evaluated using the data of the Lithuanian Cancer Registry for 1998 - 2002 . -
pubmed
CONCLUSIONS : The survival of
patients with
testicular cancer in Lithuania was substantially lower than in other European countries . -
pubmed
Anterior surgery in selective
patients with massive
ossification of posterior longitudinal ligament of cervical spine : technical note . -
pubmed
CONCLUSION : Anterior surgery using our technique may be a relatively simple and safe procedure in selective
patients with massive
ossification of posterior longitudinal ligament of cervical spine . -
pubmed
Central lymph node metastases are a very common problem in
WDTC , being present in up to 90 % of
patients . -
pubmed
This study was performed to determine the influence of
tumor grade and histology on the glycolytic phenotype of
epithelial ovarian cancer patients . -
pubmed
MATERIAL AND METHODS : We identified 238
patients with
squamous intraepithelial lesions / cervical intraepithelial neoplasia (
CIN ) who were treated by loop electrocautery excision ( LEEP ) or conventional cold - knife conization ( CKC ) . -
pubmed
Samples collected from the Andhra Pradesh coast displayed a slightly higher prevalence of
WSSV and
MBV infection than those collected from Tamil Nadu , although this difference was not statistically significant ( P & gt ; 005 ) . -
pubmed
In addition , it was found that the prevalence of both
WSSV and
MBV infections fluctuated according to season . -
pubmed
The aim of our study was to screen for
liver disease among
type 1 diabetic children . -
pubmed
METHODS :
Children with
type 1 diabetes following in clinic have been examined for existence of
liver disease , from November 2008 to November 2009 . -
pubmed
RESULTS : 106
children with
type 1 diabetes were studied : age ranged between 8 months to 15.5 years , sixty two
patients were females . -
pubmed
Twenty two
patients ( 21 % ) were identified to have abnormal findings on ultrasound of the liver : 10
patients had
hepatomegaly and 12 had hyperechogenic liver . -
pubmed
CONCLUSIONS : Hyperechogenic liver and/or
hepatomegaly are not uncommon in
children with
type 1 diabetes and tend to be more prevalent among
children with poor glycemic control . -
pubmed
Because of its safety , and reliability , ultrasound can be used to screen for
hepatopathy in
type 1 diabetic child . -
pubmed
Methadone for
chronic non - cancer pain in
adults . -
pubmed
Both RCTs were cross - over studies , one involving 19
participants with diverse
neuropathic pain syndromes , the other involving 76
participants with
postherpetic neuralgia . -
pubmed
The non - randomized study found that in
patients initially prescribed
methadone it was effective in fewer participants than in those initially prescribed other long - acting opioids ( 28 % versus 42 % , 33 % and 50 % for
morphine ,
oxycodone and transdermal
fentanyl , respectively).One RCT compared incidences for several individual adverse events , but found a difference between
methadone and placebo for only one event ,
dizziness ( P = 0.041 ) . -
pubmed
CASE REPORT : The authors report the case of a
woman with recent - onset grade I
hypertension , who was referred to our staff for sonographic studies of the kidneys and urinary tract . -
pubmed
The case reported here underlines the importance of using color Doppler ultrasound when obstructive
uropathy is suspected , especially in
patients who have undergone renal biopsy . -
pubmed
An international longitudinal registry of
patients with
atrial fibrillation at risk of
stroke ( GARFIELD ): the UK protocol . -
pubmed
Reconstruction of a collapsed dental arch in a
patient with severe
periodontitis . -
pubmed
A Japanese
man ( age , 40 years 7 months ) had an
anterior crossbite , a collapsed occlusion , and severe
periodontitis . -
pubmed
Here , we study the genetic cause of his
albinism and making use of whole genome sequencing data we find a higher inbreeding coefficient compared to other
gorillas . -
pubmed
This transporter is known to be involved in
oculocutaneous albinism type 4 (
OCA4 ) in
humans . -
pubmed
The demographic and clinical features of the
patients , birth complications ,
infection rates and rates of neonatal intensive care unit attendance were evaluated . -
pubmed
Birth trauma was observed in three
patients ( 1.6 % ) as one
brachial nerve paralysis , one
cord rupture and one cephal
hematoma . -
pubmed
Prognostic factors in elderly
osteosarcoma patients : a multi - institutional retrospective study of 86 cases . -
pubmed
BACKGROUND : The occurrence of
osteosarcoma in elderly
patients has recently been increasing , and the outcome is poor . -
pubmed
This multi - institutional retrospective study was conducted to investigate clinical features and prognostic factors in
patients older than 40 years with
osteosarcoma . -
pubmed
METHODS :
Patients with conventional high - grade
osteosarcoma older than 40 years were recruited to this study . -
pubmed
Although
patients without
metastasis who received definitive surgery were regarded as good candidates for chemotherapy , the addition of chemotherapy did not have any impact on the outcome ( yes 63.4 % ; no 65.2 % ; p = 0.511 ) . -
pubmed
CONCLUSIONS : The present study revealed the distinct clinical features , such as the high incidence of truncal
tumors or
metastasis at diagnosis , in
patients older than 40 years with
osteosarcoma . -
pubmed
Efficacy and safety of renal denervation in elderly
patients with resistant
hypertension . -
pubmed
Elderly
patients with
rHTN should not be excluded from renal denervation . -
pubmed
Out of these , 33 ( 75 % ) , 36 ( 51.4 % ) , and 48 ( 73.8 % ) from
wounds , skin , and bed , respectively , were found to be
methicillin - resistant
Staphylococcus aureus (
MRSA ) using the disc - sensitive test methods . -
pubmed
The proportion of
patients with symptomatic
gastroesophageal reflux disease increased from 12.8 % to 27.4 % . -
pubmed
Our study provides a new rationale for combining metronomic chemotherapy with adoptive cell immunotherapy in the treatment of xenograft
NSCLC tumors in immunodeficient
mice . -
pubmed
Viridans streptococci were the most common cause of
IE ( 32 % ) , followed by
Staphylococcus aureus ( 24 % ) . -
pubmed
The risk of
stroke was higher in those with
endocarditis caused by
S. - pubmed
As part of that effort , the Agency will need to address the fact that while a National Toxicology Program ( NTP ) chronic inhalation bioassay of
V2O5 produced clear evidence of treatment - related
lung tumors in both male and female
B6C3F1 mice , neither of these responses were dose - related across the groups exposed to 1 , 2 , and 4mg / m(3 ) . -
pubmed
Herein we report results from computing poly-3 - adjusted Cochran - Armitage trend test statistics with and without inclusion of the
lung tumor incidence data from control group
mice . -
pubmed
These results confirm the absence of any significant dose - related effect on
mouse lung tumor incidence in the study groups exposed to
V2O5 . -
pubmed
This prescription must consider contraindications and medical conditions for safe insertion , especially to avoid
infection by screening
STD (
Chlamydia trachomatis and
Nesseria gonorrhoeae ) in nulliparous women<25 years old . -
pubmed
This report presents use of presurgical compression and prophylactic passive pressure therapy with acrylic appliances for
auricular keloids in a
patient . -
pubmed
Her hospital course included
Staphylococcus epidermidis bacteremia , for which broad spectrum antibiotics were prescribed . -
pubmed
Three previously treated
ATL patients , classified as intermediate- to high - risk , were subcutaneously administered with the vaccine , consisting of autologous dendritic cells ( DCs ) pulsed with Tax peptides corresponding to the CTL epitopes . -
pubmed
Shigella is the main cause of
bacillary dysentery with around 160 million annual cases , while
EIEC generally induces a milder disease compared to Shigella . -
pubmed
Caenorhabditis elegans killing- and bacterial colonization assays were performed to examine the potential difference in virulence between Shigella and
EIEC strains . -
pubmed
Shigella dysenteriae serotype 1 which carries the Shiga toxin showed the lowest nematode survival rate at 82.6 + - 3.97 % and highest bacterial colonization of 1.75 x 10(5 ) + - 8.17 x 10(4 ) CFU ml(-1 ) , whereas a virulence plasmid - negative Shigella
strain demonstrated 100 + - 0 % nematode survival and lowest bacterial accumulation of 1.02 x 10(4 ) + - 7.23 x 10(2 ) CFU ml(-1 ) . -
pubmed
Efficacy of
edaravone on coronary artery bypass
patients with
myocardial damage after
ischemia and reperfusion : a meta analysis . -
pubmed
METHODS : We included randomized controlled trials that compared
edaravone with placebo or no intervention in
patients with acute
myocardial infarction or undergoing coronary artery bypass . -
pubmed
Risk of
oral and gastrointestinal mucosal injury in
patients with
solid tumors treated with
everolimus ,
temsirolimus or
ridaforolimus : a comparative systematic review and meta - analysis . -
pubmed
BACKGROUND : The authors performed a systematic review and meta - analysis of
diarrhea and
stomatitis associated with the use of
everolimus ,
temsirolimus or
ridaforolimus in
patients with
solid tumors . -
pubmed
PATIENTS AND METHODS : Eligible studies included randomized trials of
patients with
solid tumors on
everolimus ,
temsirolimus or
ridaforolimus , describing the events of
diarrhea and
stomatitis . -
pubmed
We examined patterns of cortical thickness loss and cognitive decline over time in 19
patients with
Alzheimer ' s disease (
AD ) , 10 with
behavioral variant frontotemporal dementia (
bvFTD ) , and 34 controls with a mean interval of 2.1 + - 0.4 years . -
pubmed
Decrease of thickness over time was highest in
AD and generalized throughout the whole brain , most pronounced posteriorly , whereas
bvFTD patients had a more selective loss in frontal cortex and in anterior parts of the temporal lobes . -
pubmed
In a direct comparison ,
AD patients showed faster cortical thinning in the insula , temporal , and parietal regions , whereas
bvFTD patients only showed faster cortical thinning in the orbitofrontal gyrus . -
pubmed
Decline of cognitive performances was in line with cortical thinning and deteriorated the most in
AD patients . -
pubmed
Despite promising short - term results and emerging arthroscopic techniques , it remains unclear whether
patients benefit from surgical correction in the mid- to long - term and whether progressive
joint degeneration can be prevented . -
pubmed
Of these 44
patients , 39 were treated with correction of the femoral offset for isolated
cam deformity , 5 with additional focal pincer correction and partial labral resection . -
pubmed
CONCLUSIONS : Arthroscopic correction of
femoroacetabular impingement results in a persistent clinical improvement without significant progression of degenerative changes in the majority of
patients . -
pubmed
Clinical profile of
patients with
traumatic cervical spine injury in the emergency department of a tertiary care hospital . -
pubmed
However , studies in
human revealed that prolonged consumption of this plant led to dependence and tolerance while cessation caused a series of aversive
withdrawal symptoms . -
pubmed
PURPOSE : The purpose of this study was to determine the efficacy and feasibility of surgical management of
children with
thoracolumbar spine tuberculosis with
kyphosis by using one - stage posterior focus debridement , interbody grafts , and posterior instrumentation and fusion . -
pubmed
METHODS : From October 2010 to September 2013 , 21
children with
thoracolumbar spinal tuberculosis accompanied by
kyphosis were treated with one - stage posterior decompression , interbody grafts , and posterior instrumentation and fusion . -
pubmed
Patients were evaluated before and after surgery in terms of ESR , neurologic status ,
pain , and kyphotic angle . -
pubmed
RESULTS :
Spinal tuberculosis was completely cured , and the grafted bones were fused in all 21
patients . -
pubmed
Pain relief was obtained in all
patients . -
pubmed
CONCLUSIONS : Our results show that one - stage posterior decompression , interbody grafts , and posterior instrumentation and fusion were an effective treatment for
children with
thoracolumbar spinal tuberculosis . -
pubmed
METHODS : The records of 432
patients with
RCC who underwent radical or partial nephrectomy between 2005 and 2014 were retrospectively reviewed . -
pubmed
BACKGROUND :
Trauma - induced coagulopathy (
TIC ) is commonly seen among
patients with severe
injury . -
pubmed
RESULTS : We identified 53
patients with a diagnosis of
sub - epidermal autoimmune blistering disease . -
pubmed
Twenty - eight
patients had abnormal values of
eosinophilia , extremely susceptible to systemic
steroid therapy . -
pubmed
Allergic contact dermatitis caused by
panthenyl ethyl ether in a
patient with
psoriasis . -
pubmed
In this study , we used stochastic dynamic causal modeling ( sDCM ) to quantify connections among the left dorsolateral prefrontal cortex ( inner speech monitoring ) , auditory cortex ( auditory processing ) , hippocampus ( memory retrieval ) , thalamus ( information filtering ) , and Broca 's area ( language production ) in 17 first - episode drug - naive
SZ patients with
AVHs , 15 without
AVHs , and 19 healthy controls using resting - state functional magnetic resonance imaging . -
pubmed
sDCM revealed an increased sensitivity of auditory cortex to its thalamic afferents and a decrease in hippocampal sensitivity to auditory inputs in
SZ patients with
AVHs . -
pubmed
CONTEXT : Two - thirds of
patients undergoing coronary artery bypass grafting ( CABG ) surgery report moderate to severe
pain , particularly with ambulatory or respiratory effort . -
pubmed
The
pain was assessed at 4 h after extubation when the
patient was fully awake , then at 8 , 12 , 18 , and 24 h. Both groups received intravenous
tramadol 100 mg as rescue analgesia whenever visual analog scale score was 5 and above . -
pubmed
This study aimed to develop a predictive model of
POAF based on preoperative transthoracic echocardiography ( TTE ) findings in these
patients . -
pubmed
Results : Thirty - seven ( 12 % )
patients developed
POAF . -
pubmed
Copper accumulation in parts of the brain accompanied by some neurologic involvement was revealed in LEC
rats and tx / tx - j
mice , but the pathology is less severe than
human neurologic WD . -
pubmed
Several
dogs show
hepatic copper toxicity resembling
WD ; however , brain involvement has not been observed and the underlying
genetic defect is different . -
pubmed
Findings made by
animal studies may facilitate the development of specific therapies to ameliorate
WD progression . -
pubmed
Pathogenic endoparasites of the
spotted seatrout ,
Cynoscion nebulosus : patterns of
infection in estuaries of South Carolina , USA . -
pubmed
Six types of pathogenic endoparasites in an economically important fish ,
spotted seatrout Cynoscion nebulosus , were studied in order to test whether prevalence of
infection and assemblage richness varied with season , host sex , host size , or host age . -
pubmed
Treatment adherence during childhood in
individuals with
phenylketonuria : Early signs of treatment discontinuation . -
pubmed
Analyze how treatment adherence evolves through infancy , childhood , and early adolescence in
individuals with
PKU . -
pubmed
Individuals can be either
CD177 - deficient or harbor distinct CD177neg and CD177pos neutrophil subsets . -
pubmed
vignicola
strains cause bacterial blight of the legume crop
cowpea . -
pubmed
Changes in gene expression in
chronic allergy mouse model exposed to natural environmental PM2.5 - rich ambient air pollution . -
pubmed
In the present study , we aimed to investigate the cellular responses induced by exposure to natural ambient air pollution , employing a
mouse model of
chronic allergy . -
pubmed
Significantly higher frequencies of
anemia ,
hematinic deficiencies ,
hyperhomocysteinemia , and serum gastric parietal cell antibody positivity in
atrophic glossitis patients . -
pubmed
Of the 202 anemic
AG patients , 22 had
pernicious anemia , eight had
macrocytic anemia rather than
pernicious anemia , 117 had
normocytic anemia , 30 had
iron deficiency anemia , and 21 had
thalassemia trait - induced
anemia , and four had
microcytic anemia rather than
iron deficiency anemia and
thalassemia trait - induced
anemia . -
pubmed
The
normocytic anemia and
iron deficiency anemia are the two most common types of
anemia in our 1064
AG patients . -
pubmed
PURPOSE :
Patients with
localized muscle - invasive bladder cancer (
MIBC ) can choose to undergo either neoadjuvant chemotherapy followed by radical cystectomy or radiation therapy - based bladder preservation treatment modality with subsequent close cystoscopic surveillance with salvage cystectomy reserved for
patients with evidence of local disease
recurrence . -
pubmed
Once validated , biological markers will help clinicians tailor the management of
MIBC to individual
patients . -
pubmed
Accumulating evidence suggests that microRNA-326 ( miR-326 ) serves as a
tumor suppressor in the initiation and progression of several
human malignancies . -
pubmed
Downregulation of miR-326 was closely associated with aggressive progression and poor prognosis of primary
PCa patients . -
pubmed
Overexpression of miR-326 also suppressed
tumor growth in xenografted
nude mice in vivo . -
pubmed
RESULTS : We identified 129
HHD patients ; 104 ( 81 % ) were followed for & gt;=6 months . -
pubmed
With relatively rapid training ,
HHD should be considered in more
patients . -
pubmed
Here , we report the annotated draft genome sequences of six type
strains of the family Eggerthellaceae ,
Gordonibacter faecihominis JCM 16058 ,
Paraeggerthella hongkongensis DSM 16106 ,
Parvibacter caecicola DSM 22242 ,
Slackia equolifaciens DSM 24851 ,
Slackia faecicanis DSM 17537 , and
Slackia isoflavoniconvertens DSM 22006 . -
pubmed
The
obesity - increased macrophage infiltration and lipotoxicity was decreased in
mouse kidney after miR-155 sponge treatment . -
pubmed
Neuroanatomical and functional alterations of insula in mild
traumatic brain injury patients at the acute stage . -
pubmed
To explore this hypothesis , we investigated early alterations in the gray matter volume ( GMV ) and brain functional connectivity ( FC ) of insula in
mTBI patients within 7 days after
injury and any possible correlations with cognitive function . -
pubmed
A total of 58
mTBI patients at the acute stage and 32 matched healthy controls were recruited and underwentT1 - weighted magnetic resonance imaging ( MRI)andresting - state functional MRI scans within 7 days of
injury . -
pubmed
We found that the GMV was significantly reduced only in the right insula in
mTBI patients and no significant GMV increase was observed in either hemisphere . -
pubmed
mTBI patients demonstrated decreased FC in the right parahippocampal gyrus and increased FC in the right supramargianl gyrus . -
pubmed
In addition , compared to the healthy controls , the
mTBI patients in the acute stage presented a decline in the visuospatial / executive ( p = 0.013 ) and attention ( p = 0.038 ) subcategories . -
pubmed
Our data demonstrated alterations of the GMV and resting - stateFC of the right insula in
mTBI patients at the acute stage . -
pubmed
Mouse Model of Mutated in
Colorectal Cancer Gene Deletion Reveals Novel Pathways in
Inflammation and
Cancer . -
pubmed
davaonensis was not observed in recombinant
strains of
B. - pubmed
14 mg / l )
roseoflavin was produced with recombinant
strains of
C. - pubmed
A description is given of a
patient suffering from
MD1 with a number of
endocrine disorders , including
hypergonadotropic hypogonadism ,
autoimmune thyroid disease ,
hyperinsulinism , and also impaired
calcium -
phosphorus metabolism . -
pubmed
Patients with
PMV were associated with increased blood transfusions , more consumption of
vasopressin and antipulmonary
hypertension medication , higher incidence of reintubation , more renal replacement treatment , longer intensive care unit stay , greater hospitalization costs , and more specialist visits . -
pubmed
METHODS : Phase I , randomized , double - blind , single - dose , three - period , six - sequence cross - over , multi - center study to evaluate the pharmacokinetics , pharmacodynamics , safety , and
immunogenicity of Sandoz biosimilar
pegfilgrastim with US- and EU - references in healthy
adults . -
pubmed
CASE PRESENTATION : A 27 - year - old
woman at 31 + 5 weeks ' gestation presented to the emergency department with a three - day history of the left lower
abdominal pain . -
pubmed
With the provisional diagnosis of
adnexal torsion , the
patient was taken to surgery . -
pubmed
Brucellosis is a serious
zoonosis occurring mainly in developing countries , and its diagnosis is largely dependent on serologic detection and
bacterial culture . -
pubmed
The high stability of the tested agents in
human plasma will most likely result in long - lasting
poisoning in vivo , having relevant consequences for the treatment regimen . -
pubmed
An echocardiogram was performed in 170
hypertensive patients and 20 healthy individuals . -
pubmed
The Impact of Beta Blockers on Survival Outcomes in
Patients With
Non - small - cell Lung Cancer Treated With Immune Checkpoint Inhibitors . -
pubmed
We investigated
patients with
lung cancer who concomitantly used beta blockers and immune checkpoint inhibitors ( ICIs ) , with the hypothesis that beta blockade would positively impact clinical outcomes . -
pubmed
PATIENTS AND METHODS : We retrospectively reviewed the health records of 109
patients who were treated at Northwestern University from January 2014 through August 2018 with ICIs for
non - small - cell lung cancer (
NSCLC ) . -
pubmed
RESULTS : Among 109
patients treated with ICIs for
NSCLC , 28 of them were concomitantly prescribed beta blockers . -
pubmed
CONCLUSIONS : Our data suggests beta blocker use may be associated with improved PFS among
patients treated with ICIs for
NSCLC . -
pubmed
Methods : In the current study , we evaluated resting - state functional MRI ( rsfMRI ) data and neuropsychological assessments for various cognitive functions in a cohort with 84 early
PD patients from the Parkinson 's Progression Markers Initiative ( PPMI ) . -
pubmed
Results : Our study demonstrated that in the early
PD patients , scores of Letter Number Sequencing ( LNS ) were positively correlated with EC in the left inferior occipital gyrus ( IOG ) and lingual gyrus . -
pubmed
Influence of
Omega-3 Fatty Acid - Rich
Fish Oils on
Hyperlipidemia : Effect of Eel , Sardine , Trout , and Cod Oils on
Hyperlipidemic Mice . -
pubmed
The anti -
hyperlipidemic effect of selected
fish oils (
eel ,
sardine ,
trout ,
cod liver ) was comparatively evaluated in a high fat diet ( HFD)-fed
mouse model . -
pubmed
At the end of 30 days on the HFD , all
animals were
hyperlipidemic and were switched to a diet consisting of 90 % standard
rodent chow plus 10 % of oil from
eel ,
sardine ,
cod liver , or
trout . -
pubmed
The
fish oils tested here for effects on
hyperlipidemia vary in per cent of
omega-3 FAs and
omega-6 /- 3 FA ratios as determined by gas chromatography Overall , smoked
eel was the best source of
omega-3 FA , with a balance of
omega-6 FA , that ameliorated HFD - induced mixed
hyperlipidemia . -
pubmed
OBJECTIVE : The
cytotoxic effect of
bersaldegenin-1,3,5 - orthoacetate - a
bufadienolide steroid occuring in
plants from
Kalanchoe genus (
Crassulaceae ) , was evaluated with
cervical cancer HeLa cells in vitro . -
pubmed
We aimed to investigate the associations of the level and increase in D - dimer between baseline and 90 days with all - cause
death or poor functional outcome in
patients after
ischemic stroke or
transient ischemic attack . -
pubmed
The present substudy included 10 518
patients within 7 days ( baseline ) of
ischemic stroke or
transient ischemic attack and 6268
patients at 90 days . -
pubmed
Conclusions Our study shows that high level and an increase in D - dimer between baseline and 90 days are associated with poor outcomes in
patients after
ischemic stroke or
transient ischemic attack . -
pubmed
Results : The Korean
patients with
MacTel type 2 were predominantly female ( 75 % ) , and the mean logMAR visual acuity was 0.282 + - 0.280 at initial presentation . -
pubmed
The objective of this study is to determine whether middle - aged
adults prescribed a low
carbohydrate - high fat ( LCHF ) or low fat ( LF ) diet would have greater loss of central fat and to determine whether the
insulin resistance ( IR ) affects intervention response . -
pubmed
Evidence of
hyperthyroidism such as
weight loss , elevation of rectal temperature , increased heart rate and
oxygen consumption , was observed in all treated
rats . -
pubmed
1,4,5,6,8 - Pentaazaacenaphthylene-3 - amino-1,5 - dihydro-5 - methyl -( 5 - 14C )- 1 - beta - D - ribofuranysly (
NSC-154020 ) , a
tricyclic 7 - deazapurine nucleoside (
TCN ) , was rapidly incorporated into the acid - soluble pool by cultured Novikoff
rat hepatoma cells ,
mouse L - cells ,
HeLa cells , and
HEp-2 cells , but little incorporation into nucleic acids occurred . -
pubmed
Netilmicin , a new
aminoglycoside antibiotic , has increased in vitro bactericidal activity against many
strains of
Enterobacteriaceae as compared to other
aminoglycosides . -
pubmed
No
ototoxicity was observed in two
patients whose treatment required inordinately high serum levels and in whom other risk factors were present . -
pubmed
Ototoxicity in 1 of 21
patients studied was unilateral , partially reversible , and not associated with high serum levels . -
pubmed
Although
nephrotoxicity occurred in 4 of 25
patients ( 16 % ) , other host factors could have accounted for the
toxicity in two
patients . -
pubmed
Long - term follow - up of twenty - six
patients with unicameral
bone cysts treated by curettage and packing with plaster - of - Paris pellets showed a
recurrence in only two cases and no serious complications . -
pubmed
Reticulo - endothelial phagocytosis in
patients with
nephritis . -
pubmed
In Nallur , which was endemic for
JE and had a large
pig population , 4.4 - 5.4 % of the feedings were on these hosts . -
pubmed
By intravenous application of the specific
Quisqualate antagonist
glutamic acid diethyl ester (
GDEE ) 77.2 % of our
patients with cochlear synaptic
tinnitus noted a
tinnitus reduction . -
pubmed
The dimensions of the
aneurysms ( transversal diameter and length ) were greater in
hypertensive than in normotensive
animals ( F = 11 , P less than 0.001 ) and aneurysmal dimensions were positively correlated with the level of blood pressure ( r = 0.56 , P less than 0.001 ) . -
pubmed
Protection by
schisanhenol against
adriamycin toxicity in
rat heart mitochondria . -
pubmed
The effects of
schisanhenol (
Sal ) on
Adriamycin (
ADM)-induced
rat heart
mitochondrial toxicity in vitro were investigated . -
pubmed
These results indicate that
Sal could protect against
ADM - induced
rat heart
mitochondrial toxicity . -
pubmed
The content of
cyclic nucleotides in blood plasma was measured in 151
patients suffering from
rheumatoid arthritis . -
pubmed
RA patients untreated with glucocorticoids manifested significant correlations between the content of
cyclic nucleotides and some characteristics of
inflammation and of the immune status . -
pubmed
Treatment with
1 alpha - hydroxyvitamin D3 and
phosphates was associated with acceleration of growth in all
children , healing of
rickets in 21 , and normalization of the serum
phosphate in 22 . -
pubmed
This study was undertaken to evaluate the efficacy and the safety of transnasal
butorphanol (
TNB ) compared to intravenous
butorphanol (
IVB ) in 186
patients experiencing moderate to severe
post - cesarean section pain . -
pubmed
High therapeutic efficacy was demonstrated in experimental
mice septicemias with the
2 -( 3 - pyridyl ) derivative 2b and its orally absorbed
acetoxymethyl ester prodrug 4n . -
pubmed
A single episode of
systemic capillary leak syndrome is reported in a
HIV - positive
patient . -
pubmed
Therefore , it appears reasonable to monitor muscular pressure during volume expansion in
patients with
capillary leak syndrome , severe
shock and
muscular swelling . -
pubmed
The possibility can not be excluded that the natural exposure of
humans to SPM in the environmental atmosphere may explain the high prevalence rate of
allergic rhinitis caused by pollens in polluted districts in Japan . -
pubmed
After DR for various periods ,
kittens were subsequently exposed to light so as to trigger the onset of the
CP that had been postponed . -
pubmed
One is a 45 - year - old
man with
Philadelphia - positive CML , and the other a 74 - year - old patient with
Philadelphia - negative CML . -
pubmed
The test is therefore likely to be of value in the correct diagnosis of the cause of
renal dysfunction and thereby improve the management of
cyclosporine - treated renal transplant
patients . -
pubmed
All four patients in this study had a
cardiomyopathy , and
heart disease was the cause of
death in two of the
patients . -
pubmed
Like radioimmunoassay , immunoenzyme assay permits detecting
myoglobinemia both in healthy persons and in
patients with
acute myocardial infarction (
AMI ) . -
pubmed
In
AMI patients ,
myoglobinemia reaches a maximum 5 to 12 hours since the onset of a powerful
anginal attack whereupon it gradually and spasmodically decreases , without returning to normal toward outcome of the 3d day of the observation period . -
pubmed
A single assay of
myoglobinemia in
AMI patients is of diagnostic importance within 2 to 27 hours since the disease onset . -
pubmed
After three to four hours of treatment , hypan achieved greater
cervical dilation among primigravid
women and only modestly increased side effects , as compared with
16 dimethyl PGE2 suppositories or laminaria tents . -
pubmed
Obese patients showed no significant differences from controls in basal and nadir
glucose , basal and peak
glucagon ,
cortisol , and thyroid responses to both tests . -
pubmed
The brains of all three
patients with
developmental dyslexia studied thus far have shown scattered small malformations primarily in the cerebral cortex of the left cerebral hemisphere . -
pubmed
In view of the possible involvement of these systems in learning suggested by these and by previous data , it seems likely that the neurohumoral regulation of habituation and avoidance learning may be different in
rats submitted to
protein malnutrition when compared to controls . -
pubmed
Anatomic - ultrasound correlations for intraoperative open chest imaging of
coronary artery atherosclerotic lesions in
human beings . -
pubmed
Ultrasound images of
coronary atherosclerotic lesions were compared with anatomic specimens of the coronary arteries obtained from open chest
human subjects . -
pubmed
The anatomic specimens were derived from four cardiac transplant recipients , accepted as candidates for transplantation because they had severe diffuse
atherosclerotic disease , and one
patient who died in the early postoperative period after a coronary artery bypass procedure . -
pubmed
Twenty - six ultrasonically imaged
atherosclerotic areas of the coronary arteries in these
patients were compared with
formalin - fixed and decalcified anatomic specimens . -
pubmed
The management of common
bile duct calculi by endoscopic sphincterotomy in
patients with gallbladders in situ . -
pubmed
Endoscopic sphincterotomy ( ES ) is widely used in the treatment of
patients with
common bile duct ( CBD ) stones following cholecystectomy . -
pubmed
In Group A 5
patients required surgery , in 3 because of technical failure and in 2 because of
empyema of the gallbladder . -
pubmed
On follow - up ( 4 - 50 months ) , 16
patients have died but in only one from
gallbladder sepsis , and one has had a cholecystectomy for
pain . -
pubmed
Arterial blood flow and resistance in the forearm of
arteriosclerotic patients . -
pubmed
Twenty
patient with severe
atherosclerotic affection of the lower limbs , but without any symptoms of involvement of their upper extremities , and twenty healthy controls were examined . -
pubmed
The resistance of
mice to a lethal
infection with
Klebsiella pneumoniae , type I , was investigated . -
pubmed
This
antigen does not appear to be related to either the K or
O antigens of
Klebsiella and is present in several
strains of
Klebsiella . -
pubmed
Ophthalmologists treating
children with
retinoblastoma need to be aware of the limitations of new forms of therapy and their complications . -
pubmed
For this reason the following case of a
child with a small
peripheral retinoblastoma that failed to respond to treatment with both cryotherapy and photocoagulation is recorded . -
pubmed
Naturally occurring and chemically induced
brain tumors of
rats and
mice in
carcinogenesis bioassays . -
pubmed
Passive transfer of
insulitis from the " BB "
rat to the nude
mouse . -
pubmed
The " BB "
rat spontaneously develops
insulitis , and an
insulin - dependent diabetic syndrome like that in
man . -
pubmed
Of 72
mice receiving single injections 37 % showed
insulitis , with 13 % of islets examined being affected , and mean intensity of 1.9 + /- 0.3 ( on a scale of 0 to 3 ) . -
pubmed
In 12
mice receiving 3 separate injections of pooled blood and spleen lymphocytes , 58 % showed
insulitis , with 17 % of islets affected , and mean intensity 2.5 + /- 0.3 . -
pubmed
Because
cocaine blocks uptake of
catecholamines and has a sympathetic potentiating effect , its use is dangerous in
patients with
hypertensive cardiovascular disease or in conjunction with sympathomimetic or alpha - modifying drugs . -
pubmed
We encountered two
patients with indolent
chronic B - cell leukemia showing overlapping features of these
malignancies . -
pubmed
PATIENTS : Consecutive series of 37
patients ; 29 with chronic
sinusitis , five with chronic
dacryocystitis , one with recurrent
choanal stenosis , one with
tracheopathia osteoplastica , and one with a
sphenoid sinus mucocele . -
pubmed
RESULTS : Complications occurred in eight
patients : intranasal or ethmoid
scarring ( four ) , persistent
polyps ( one ) ,
bleeding ( one ) ,
stent dislodgment ( one ) , and
tracheitis ( one ) . -
pubmed
This study was undertaken to expand the current knowledge of the life cycle and adult morphology of the avian schistosome
Austrobilharzia variglandis , which causes a marine
cercarial dermatitis in New England . -
pubmed
The specific objectives were to : ( 1 ) investigate the seasonality of the
infection in the molluscan intermediate host ,
Ilyanassa obsoleta ; ( 2 ) determine which bird species are acting as natural definitive hosts for the parasite ; and ( 3 ) characterize the morphology of the parasite using scanning electron microscopy ( SEM ) . -
pubmed
Ilyanassa obsoleta was found to maintain a relatively low prevalence of
infection ( 0.7 - 5.1 % ) throughout the 14 - mo study , but no fully developed cercaria were visible in sporocysts recovered from snails collected in winter months . -
pubmed
For the purpose of follow - up of the disease as well as the availability of magnetic resonance imaging ( MRI ) as a method for diagnosing soft tissue changes 20
patients with imminent and manifest
compartment syndrome were examined for their fluid content of the lower limb . -
pubmed
The
patients with imminent
compartment syndrome and fasciotomy ( r = 0.83 , p & gt ; 0.001 , n = 19 ) demonstrated no significant changes compared to the normal volunteers ( r = 0.91 , p & gt ; 0.001 , n = 40 ) as well as the normal compartments of the diseased lower extremities ( r = 0.85 , p & gt ; 0.001 , n = 32 ) . -
pubmed
OBJECTIVE : To describe a series of consecutive
patients with
fulminant hepatic failure (
FHF ) and to present a new classification system for
brain edema , an important cause of mortality in such
patients . -
pubmed
DESIGN : We reviewed 22 computed tomographic ( CT ) scans of the brain in 12
patients with
FHF and classified the severity of
cerebral edema by using predefined criteria . -
pubmed
Three of the four
patients who had stage 1 or 2
hepatic encephalopathy at the time of initial assessment ultimately had a good outcome . -
pubmed
Of seven
patients with stage 3
encephalopathy , two had rapid deterioration to
brain death , three died of nonneurologic causes , and two had a good outcome after liver transplantation . -
pubmed
One
patient with stage 4
hepatic encephalopathy died , and autopsy showed
cerebral edema . -
pubmed
The clinical and radiologic signs of
cerebral edema in
patients who have progression to stage 3
hepatic encephalopathy can be reversed with conventional treatment of increased intracranial pressure . -
pubmed
Whether early recognition and treatment of
cerebral edema result in increased survival of
patients with
FHF remains to be determined . -
pubmed
Selective in vivo antagonism of
pinacidil - induced
hypotension by the
guanidine U37883A in anesthetized
rats . -
pubmed
Tumors in St. Lawrence
beluga whales (
Delphinapterus leucas ) A population of 450 - 500 belugas (
Delphinapterus leucas ) resides in the polluted estuary of the St. Lawrence River . -
pubmed
Overall , 28 of the 75 confirmed
tumors reported so far in cetaceans ( 37 % ) were from this small population of
beluga whales in the St. Lawrence Estuary . -
pubmed
Between 1980 and 1990 , 25
patients were treated for large
incisional hernias using the skin lacing technique . -
pubmed
Correlation between function and structure in "
epileptic "
human hippocampal tissue maintained in vitro . -
pubmed
In addition , we observed a distinctive early hemodynamic profile for
patients with strep
TSS that was unlike that for patients who had typical gram - negative
septic shock ; this profile was consistent with toxic
cardiomyopathy ( i.e. -
pubmed
Herein we present the results of pudendal canal decompression ( PCD ) , performed for the treatment of
FI in 21
patients whose
CRP was corrected by Ivalon sponge rectopexy 5.2 years before presentation . -
pubmed
Postoperatively , seven ( 53.8 % ) of the
patients with partial FI showed full fecal control with normalization or improvement of the
perianal hypoesthesia , rectal neck pressure , EMG of EAS and LA , as well as PNTML . -
pubmed
We extracted massive disciform
subretinal lesions in eight eyes of seven
patients with age - related
macular degeneration via pars plana access . -
pubmed
The chronic administration of
docosahexaenoic acid reduces the spatial
cognitive deficit following transient
forebrain ischemia in
rats . -
pubmed
The purpose of this study was to investigate whether chronic administration of
docosahexaenoic acid is able to reduce spatial
cognitive deficit following transient
ischemia in
rats . -
pubmed
Rats were subjected to 10 min of transient
forebrain ischemia by the method of four -
vessel occlusion and were tested in a radial eight - arm maze task after cerebral reperfusion . -
pubmed
A comprehensive evaluation of myelination during normal
human development is essential to understand the pathology of
congenital diseases of white matter . -
pubmed
By contrast ,
alpha - phenyl - tert - butyl nitrone did not significantly reduce the drug - induced
rotation asymmetry in
rats with a
3 - nitropropionic acid lesion . -
pubmed
The behavioural studies revealed that the combination of multiple lesions seen in
3 - nitropropionic acid - lesioned
rats significantly exacerbated paw - reaching deficits and
amphetamine - induced
rotation asymmetry . -
pubmed
The intrastriatal injection of
3 - nitropropionic acid led to degeneration of both intrinsic striatal neurons and the nigrostriatal dopaminergic system , suggesting that this lesion may provide an
animal model of a form of
multiple system atrophy rather than
Huntington ' s disease . -
pubmed
Mouse models will be powerful tools in the study of
human PWS phenotype and imprinting mechanisms . -
pubmed
One thousand one hundred and twenty - seven
patients with
vascular lesions were followed by the Department of Pediatric Oncology , Hacettepe University , for 19 years . -
pubmed
The distribution of the
vascular lesions was as follows : 969
patients had
hemangiomas , 120 had
lymphatic malformations , 18 had combined
vascular malformations , 11 had
venous malformations , six had port - wine stain , and three had
angiokeratoma . -
pubmed
METHODS :
Patients ( 18 - 80 yr ) with a culture proven
H. - pubmed
RESULTS : A total of 104
patients , 54
men , age 54+/-14 yr , ( 36
duodenal ulcer , 16
gastric ulcer , and 52
functional dyspepsia ) were included . -
pubmed
The effect of manual lung hyperinflation and postural drainage on pulmonary complications in mechanically ventilated
trauma patients . -
pubmed
Three
patients with advanced
systemic sclerosis and recurrent or incessant monomorphic
ventricular tachycardia underwent cardiac electrophysiologic studies . -
pubmed
As expected for environmental isolates , all
strains had a
Lactococcus lactis subsp . - pubmed
Twenty - four
patients ( 38 % ) had
pancreatic disorders : acute
pancreatitis ( n = 20 ) ,
chronic calcifying pancreatitis ( n = 2 ) , and
pancreatic carcinoma ( n = 2 ) . -
pubmed
The incidence of acute
pancreatitis was significantly higher in
patients with an abnormal pancreatogram , particularly dilatation , protein plugs or stones of the common channel or main pancreatic duct , and coexisting
pancreatic ductal anomaly . -
pubmed
All
patients with
choledochal cyst underwent
cyst excision and hepaticojejunostomy . -
pubmed
Eleven
patients without
choledochal cyst or pancreatobiliary
carcinoma underwent cholecystectomy alone . -
pubmed
No
patients experienced
pancreatitis during a mean postoperative follow - up of 6.7 years . -
pubmed
The incidence of benign mesothelial cells in mediastinal lymph nodes in
patients with a history of
pericarditis or
pleuritis is reported in this study . -
pubmed
Alopecia areata - like
hair loss in C3H / HeJ
mice and DEBR
rats can be reversed using topical
diphencyprone . -
pubmed
This study demonstrates the ability to treat successfully
alopecia areata - like
hair loss in both
mouse and
rat models using topical immunotherapy with
diphencyprone . -
pubmed
While intensive farming practices have been linked with the rise in
foodborne illness in
humans , it is interesting to note that the rise has continued even when there has been a shift to less intensive farm production systems . -
pubmed
Thirty - two eyes of 16 consecutive
patients who underwent trabeculectomy for uncontrolled
glaucoma of various causes form the study group . -
pubmed
The first contrast - enhanced images of 80
patients with 160 focal
liver lesions (
hepatocellular carcinoma , n = 79 ;
cavernous hemangioma , n = 51 ; metastatic
tumor , n = 30 ) were then retrospectively reviewed . -
pubmed
MATERIALS AND METHODS : Sixteen pre -
eclamptic patients and 18 healthy pregnant
women were studied . -
pubmed
METHODS : This was a prospective randomized study of
patients who received general surgery consultation for
appendicitis . -
pubmed
CLINICAL FINDINGS : A total of 271
patients with a variety of underlying
malignancies received
busulfan - containing myeloablative chemotherapy prior to aPBSCT ; none of these
patients received total body irradiation . -
pubmed
Ten
individuals developed
IPS , with a median time of onset of 102 days after stem cell infusion . -
pubmed
Nine
patients diagnosed with
IPS were treated with high doses of glucocorticoids parenterally . -
pubmed
Despite heroic measures , eight
patients died of
IPS . -
pubmed
DISCUSSION : Chronic low - dose
busulfan therapy results in
lung injury in 4 - 6 % of
patients after several years of treatment and once the cumulative dosage begins to approach 3 g. High - dose , short - course
busulfan ( 16 mg / kg)-containing conditioning chemotherapy prior to aPBSCT can also be complicated by
IPS . -
pubmed
Mortality from this complication is 80 % , but some
patients survive without long - term
pulmonary sequelae following early treatment with glucocorticoids . -
pubmed
- In 237
women ( mean age 62.9+/-7.4 years )
osteoporosis was defined by a T - score at the femoral neck below -2.5 SD . -
pubmed
METHODS : Twenty adult
sheep had
AAAs surgically created by replacing a segment of the infrarenal aorta with an autologous jugular venous graft . -
pubmed
Three months later , surviving animals underwent percutaneous implantation of macroporous
polyester - covered
nitinol stents ; 3
animals with untreated
AAAs served as controls . -
pubmed
RESULTS : Seven ( 35 % )
animals died within 24 hours of causes related to the technique ; 1
animal developed
paraplegia and was sacrificed on day 1 . -
pubmed
CLINICAL CASE : A 33 - year - old
woman presented with
seizures and a
right parietotemporal syndrome of acute onset . -
pubmed
In this study , the angle and its effect on flow velocity measurements were assessed with transcranial color Doppler sonography in
patients with
MCA stenosis . -
pubmed
METHODS : Eighteen
patients ( median age , 53 y ; age range , 22 - 72 y ) who satisfied qualifying criteria ( eg , angiographically revealed unilateral MCA
stenosis of & gt ; or = 50 % ) were selected from 149 consecutive
patients enrolled in a prospective study of transcranial color Doppler sonography and cerebral digital subtraction angiography . -
pubmed
CONCLUSION : In
patients with moderate or severe
MCA stenosis , the angle of insonation can be substantial and cause large errors when flow velocities are measured without angle correction . -
pubmed
During past decades , many attempts have been made to induce or enhance tumour - specific T - cell immunity in
cancer patients by vaccination . -
pubmed
The second
patient recovered but developed
hemiparesis . -
pubmed
METHODS : VEP of 63
patients with
nasopharyngeal carcinoma were tested before , at the end of , half a year , one year , 2 years and 3 years after their radiotherapy . -
pubmed
In
animals , GM1 ganglioside has been shown to reduce some of the behavioral deficits that follow
Central Nervous System lesions . -
pubmed
[ Study of a
strain of Bacillus , pathogenic for certain insects , identifiable with
Bacillus thuringiensis Berliner ] . -
pubmed
Incidence of
venous thromboembolism in
patients undergoing craniotomy and motor mapping for
glioma without intraoperative mechanical prophylaxis to the contralateral leg . -
pubmed
OBJECT : Evidence - based reviews support the use of
venous thromboembolism (
VTE ) prophylaxis in the form of compression devices and/or stockings for
patients undergoing craniotomy . -
pubmed
In
patients undergoing craniotomy with motor mapping for
glioma , the contralateral lower extremity should remain visible so that motor responses can be accurately identified . -
pubmed
As a consequence , these
patients could be placed at a higher risk to develop
VTE . -
pubmed
The authors have quantified the incidence of
VTE in
patients undergoing craniotomy with motor mapping and have shown that there is no increased risk of developing a
VTE in the contralateral lower extremity when compression devices are not used . -
pubmed
Intraoperative
VTE prophylaxis in all
patients consisted of ipsilateral ( that is , ipsilateral to the hemisphere being mapped ) lower - extremity mechanical prophylaxis ( antiembolism stocking plus compression device ) . -
pubmed
Six
patients ( 3.3 % ) experienced
VTE . -
pubmed
Two other
patients ( 1.1 % ) only had
PE . -
pubmed
There were no
deaths from
thromboembolic complications and no statistically significant predisposition to
VTE in the contralateral lower extremity among
patients not receiving intraoperative prophylaxis . -
pubmed
CONCLUSIONS : The incidence of
VTE in
patients undergoing craniotomy with motor mapping is comparable to that in
patients receiving bilateral lower - extremity mechanical
VTE prophylaxis . -
pubmed
Furthermore , calvarial
metastases are relatively uncommon in
children compared to adults . -
pubmed
The possibility of
neuroblastoma presenting in this unique fashion and the importance of considering a chemosensitive
tumor such as
neuroblastoma in the differential diagnosis of a solitary
calvarial mass in a
child is highlighted by our report . -
pubmed
PATIENTS : Forty
patients ( 33
men and 7
women ) with moderate to severe
traumatic brain injury ( mean age , 37 + /- 16 yrs ) were studied the day after termination of mechanical ventilation ( 7 - 60 days after
trauma ) . -
pubmed
MEASUREMENTS AND MAIN RESULTS : In
traumatic brain injury patients , mean baseline and low - dose stimulation test - stimulated
cortisol levels were 17.2 + /- 5.4 microg / dL and 24.0 + /- 6.6 microg / dL , respectively . -
pubmed
CONCLUSIONS : Adrenal
cortisol secretion after dynamic stimulation is deficient in a subset of
critically ill patients with moderate to severe
head injury . -
pubmed
Our studies provide the first evidence that
human nonsecretory myeloma may result from an alteration in the light - chain constant region . -
pubmed
The goal of this study was to evaluate
ARF in a large group of
patients who received nonmyeloablative HCT . -
pubmed
ARF ( & gt;50 % decrease in
GFR ) occurred in 40.4 % of
patients over a 3 - mo period , with 4.4 % of
patients requiring dialysis . -
pubmed
METHODS : Spherical ablations of -10.00 D were performed on 11 fresh
porcine corneas using either the Technolas Keracor 217C scanning -
spot or the Nidek EC-5000 scanning - slit beam excimer laser . -
pubmed
The responses to manipulation of extracellular and intracellular
calcium are altered in the
streptozotocin -
diabetic rat colon and ileum . -
pubmed
Studies were performed to see if alterations in
Ca2 + homeostasis underlie the gastrointestinal motility complications seen in many
diabetic patients . -
pubmed
Experiments were performed on colonic and ileal tissues taken from
streptozotocin - induced
diabetic and control
rats . -
pubmed
A gene(s ) for
all - trans - retinoic acid - induced
forelimb defects mapped and confirmed to
murine chromosome 11 . -
pubmed
All - trans - retinoic acid ( RA ) induces various
anatomical limb dysmorphologies in
mice dependent on the time of exposure . -
pubmed
During early limb development ,
RA induces
forelimb ectrodactyly ( digital absence ) with varying susceptibilities for different inbred
mouse strains ; C57BL/6N are highly susceptible while SWV are resistant . -
pubmed
The
human syntenic region of this locus has been previously linked to
Meckel syndrome ; the phenotype includes
postaxial polydactyly , an
ectopic digital defect hypothesized to be induced by a common molecular pathway with
ectrodactyly . -
pubmed
There are limited data regarding the antifungal susceptibility of
yeast causing
vulvovaginal candidiasis , since cultures are rarely performed . -
pubmed
Susceptibility testing was performed on vaginal
yeast isolates collected from January 1998 to March 2001 from 429 patients with suspected
vulvovaginal candidiasis . -
pubmed
Breast tumours were induced in female
Sprague - Dawley rats by
N - methyl - n - nitrosourea ( 50 mg kg(-1 ) , i.p ) . -
pubmed
, was administered to the
tumour bearing
rats via the tail vein . -
pubmed
The AUC(0 - infinity ) ( 9.42 + /- 3.18 microg h mL(-1 ) ) , clearance ( 0.69 + /- 0.17 L h(-1 ) kg(-1 ) ) , volume of distribution ( 10.31 + /- 4.54 L kg(-1 ) ) and half life ( 1.00 + /- 0.32 h ) of
[ 3H ]- paclitaxel in
tumour rats were similar in
rats treated with
IRL 1620 or vehicle . -
pubmed
Tumour concentration of
[ 3H ]- paclitaxel was determined in
rats treated with
IRL 1620 or vehicle and there was a significant increase in
tumour paclitaxel concentration ( 308.59 + /- 24.42 % ) in
rats treated with
IRL 1620 compared with vehicle . -
pubmed
Infectious bursal disease virus (
IBDV ) causes an
immunosuppressive disease in
chickens and leads to severe economic losses in the poultry industry . -
pubmed
Phenserine also showed small , non dose - dependent effects on learning in studies in aged
rats and lower
toxicity than
physostigmine . -
pubmed
Gene expression profiling in
human cardiovascular disease . -
pubmed
Most of these studies have been successfully performed for
human cancers . -
pubmed
Inspired by these results , researchers in the cardiovascular field have also started using large - scale transcriptional analysis to better understand and classify
human cardiovascular disease . -
pubmed
Many individuals attempting to lose weight have
hypertension , especially those with
diabetes , and the prevalence of
hyperaldosteronism among hypertensive
patients is higher than previously recognized . -
pubmed
We present a
patient with
Type 2 diabetes and previously undiagnosed
hyperaldosteronism who developed life - threatening
hypokalaemia while following a low -
carbohydrate diet . -
pubmed
CASE REPORT : A 60 - year - old
man with diet - treated
Type 2 diabetes and
hypertension presented with generalized
muscle weakness and serum
potassium of 1.9 mmol / l. He had succeeded in losing three and a half stones during the previous 4 months by adhering strictly to a low -
carbohydrate diet . -
pubmed
The majority of these
people are
normokalaemic and remain undiagnosed . -
pubmed
This technique is not known to have been described previously in the diagnostic investigation of r -
PDA in
dogs . -
pubmed
METHODS : We classified 67
patients with
PPA into three clinical variants :
semantic dementia (
SEMD ) ,
progressive nonfluent aphasia (
PNFA ) , and
logopenic progressive aphasia (
LPA ) , and we compared the severity of
behavioral dysfunction , as measured by the Neuropsychiatric Inventory , in these groups and
patients with
frontotemporal dementia (
FTD ) and
Alzheimer disease (
AD ) . -
pubmed
Since cellular sensitivity of primary
human fibroblasts usually reflects clinical sensitivity such patients with
cancer would be at risk of increased toxicity . -
pubmed
In group I , all treated
animals were followed until
death to assess therapeutic effect on survival . -
pubmed
In recent decades ,
apple cider has been implicated in a series of outbreaks of
foodborne illness . -
pubmed
Twenty - seven
patients with limited
SSc (
ISSc ) without
interstitial lung involvement were studied . -
pubmed
Eighteen of 27
SSc patients presented an ex - PAP & gt ; 40 mmHg , while in 9 of 27
patients ex - PAP values remained & lt ; 40 mmHg ( 48.8 + /- 4.5 mmHg versus 36.2 + /- 3.1 mmHg ; P & lt ; 0.001 ) . -
pubmed
Further mechanistic studies and randomized controlled clinical intervention trials with
lycopene involving
cancer patients are warranted . -
pubmed
A prospective study of sentinel lymph node status and parametrial involvement in
patients with small
tumour volume
cervical cancer . -
pubmed
METHODS : After radical abdominal hysterectomy , 158 women
patients were stratified into two groups based on
tumour size : In Group 1 ( 91
women )
tumours were less than 20 mm and less than half of stromal invasion . -
pubmed
In Group 2 ( 67
women )
tumours were between 20 and 30 mm and infiltration was not more than 2/3 of cervical stroma . -
pubmed
Distraction plate
fractures , screw
loosening or absence of new bone formation were the complications encountered in the other three
patients . -
pubmed
Impact of the degree of liver resection on survival for
patients with multiple
liver metastases from
colorectal cancer . -
pubmed
RESULTS : As the
patients undergoing major resection were more likely to have multiple ( p = 0.014 ) and large
tumors ( p = 0.021 ) compared to the minor - resection
patients , their overall survival was worse ( p = 0.046 ) and the
disease - free rate tended to be poorer . -
pubmed
When patients with six or more
metastases were selected and analyzed , the overall survival of
patients who had a major resection was significantly poorer than those who had minor resections ( p = 0.028 ) , although the clinical characteristics were comparable between the two groups . -
pubmed
Twenty - eight nonobese
women with previous severe
preeclampsia and 20
women with a previous normotensive pregnancy were studied 5 to 6 years after the index pregnancy . -
pubmed
METHODS : From January 2002 to May 2007 , 18
patients with old scaphoid
fractures were treated by grafting bones from distal radius and fixing absorbable screws . -
pubmed
INTRODUCTION : There is a lack of awareness of the prevalence of
infection by
Helicobacter pylori (
HP ) and its histopathological characterization in children in Peru . -
pubmed
CONCLUSION : A high prevalence of
infection by
HP was found in
children who underwent an upper endoscopy . -
pubmed
In this pilot study , we first hypothesized levels of synovial fluid markers would be higher in
patients with
cartilage lesions than in
patients with no
cartilage lesions , and then we hypothesized the levels of synovial fluid markers would decrease after cartilage repair . -
pubmed
Fifteen
patients undergoing knee arthroscopy for various symptoms but with no apparent
cartilage lesions served as control subjects . -
pubmed
We detected reduced feed intake resulting in lower growth ,
weight gain and muscle protein accretion in
salmon fed plant protein compared to a diet based on fish meal . -
pubmed
Interactions of the autonomic nervous system with local immune cells play an important role in the development of
IBD , and the balance of autonomic nerve function is broken in
IBD patients with
sympathetic overactivity . -
pubmed
Lamina propria mononuclear cells ( LPMCs ) from
mice with TNBS
colitis were cultured in the absence or presence of
RX821002 or
UK14304 , and stimulated further by lipopolysaccharide . -
pubmed
In future it may be possible to separate the genetic , enzymatic and environmental factors that are responsible for increased vulnerability of some
individuals to
alcohol abuse ( Fig . -
pubmed
Peri- and postnatal developmental
toxicity of
salcaprozate sodium (
SNAC ) in
Sprague - Dawley rats . -
pubmed
In summary ,
SNAC administered orally at 1000 mg / kg / d to pregnant
rats from gestation to weaning resulted in a slight decrease in maternal
body weights ( -3.8 % ) and prolonged gestation , along with an increase in
stillbirths , but had no effects on growth and development in surviving offspring . -
pubmed
Although controversy remains regarding indications for
testosterone supplementation in aging men due to lack of large - scale , long - term studies assessing the benefits and risks of
testosterone - replacement therapy in men , reports indicate that TRT may produce a wide range of benefits for
men with
hypogonadism that include improvement in libido and sexual function , bone density , muscle mass , body composition , mood , erythropoiesis , cognition , quality of life and
cardiovascular disease . -
pubmed
The aim of our study was to assess the long - term safety and efficacy of
MTX in
patients with chronic severe forms of
AA totalis . -
pubmed
PATIENTS AND METHODS : Thirty - three
patients ( 24
women and nine
men ) with
AA totalis or
universalis were included . -
pubmed
Relapse was observed on
corticosteroid dose reduction or withdrawal in 16 of the 20
patients in whom total hair regrowth initially occurred . -
pubmed
Regrowth after treatment of
relapse was seen in 14 of these 16
patients ( 87 % ) . -
pubmed
Seven
patients experienced adverse events consisting of transient elevated transaminases ( n=4 ) , persistent
nausea ( n=2 ) and
lymphocytopenia ( n=1 ) . -
pubmed
CONCLUSION :
MTX alone or in combination with low doses of oral
corticosteroids resulted in complete hair regrowth in about half of these
patients presenting
AA totalis or
universalis . -
pubmed
This study evaluated whether two people with
multiple disabilities would be able to improve their pointing performance through an Automatic Target Acquisition Program ( ATAP ) and a newly developed
mouse driver ( i.e. -
pubmed
We aimed to detect the presence of
HSV 1 and 2 (
herpes simplex virus ) and
HHV8 (
human herpesvirus 8) in our patients who were suffering from
pemphigus vulgaris . -
pubmed
CONCLUSION : Inability to detect
HHV8 and
HSV DNA in this study suggests that herpesviruses may be only occasional factors for development or exacerbation of
pemphigus vulgaris . -
pubmed
Distal
embolism is the most important complication for the
patients with vulnerable
plaque , which is detected by ultrasound sonography or MRI . -
pubmed
Hyperperfusion may also occur in
patients with
impairment of the cerebrovascular reactivity , which is detected by single photon emission computed tomography ( SPECT ) with
acetazolamide challenge . -
pubmed
We should identify
patients with high risk for
CAS due to anatomy or vulnerability of the plaque to avoid periprocedural complication . -
pubmed
Daily probiotic 's (
Lactobacillus casei Shirota ) reduction of
infection incidence in athletes . -
pubmed
A high proportion of
participants with good response rates to topical treatment ( 58%-92 % ) experience local side effects such as
itching and burning , less commonly erosion and
ulceration , but the proportion of participants ceasing treatment has not been high . -
pubmed
Novel mechanisms of immune modulation of
natalizumab in
multiple sclerosis patients . -
pubmed
The goal of this study was to investigate the effects of
natalizumab therapy on the immune cell composition and phenotype in the blood of relapsing
MS patients treated over the course of 12 months . -
pubmed
We collected peripheral blood from 26
RRMS patients before treatment onset , and then 6 and 12 months after therapy . -
pubmed
These changes may help to explain both the mechanisms of action of
natalizumab and also shed light on the potential for the observed increase in
PML in these
patients . -
pubmed
METHODS : A total of 81 previously treated histopathologically proven
glioma patients ; with clinical and conventional imaging findings suspicious of
recurrence were included in this study . -
pubmed
Data was censored , if the
patient died of
disease or at the end of the study . -
pubmed
Effects of
enoxaparin in the
rat hippocampus following
traumatic brain injury . -
pubmed
Purpose of this study was to investigate the effects of low molecular weight
heparin ,
enoxaparin , on different parameters of the
hippocampal damage following
traumatic brain injury (
TBI ) in the
rat . -
pubmed
Rats were sacrificed 48h after the induction of
TBI . -
pubmed
These findings demonstrate that
enoxaparin may reduce oxidative damage ,
inflammation and
astrocytosis following
TBI in the
rat and could be a candidate drug for neuroprotective treatment of this
injury . -
pubmed
Honeycombs , bees ,
honey and
propolis from depopulated
hives were analyzed for pesticide residues , whereas from active
beehives only
honey and
propolis were evaluated . -
pubmed
Interventional Radiology ( IR ) is occupying an increasingly prominent role in the care of
patients with
cancer , with involvement from initial diagnosis , right through to minimally invasive treatment of the
malignancy and its complications . -
pubmed
Therapeutic applications of IR in the oncology
patient include local
tumour treatments such as transarterial chemo - embolisation and radiofrequency ablation , as well as management of complications of
malignancy such as
pain , organ obstruction , and
venous thrombosis . -
pubmed
METHODS : Our cross - sectional study was carried out in 10 Italian rheumatology centers between January and September 2009 , and enrolled all consecutive
patients with
PsA and
FM who agreed to participate . -
pubmed
RESULTS : Two hundred sixty - six
patients with
PsA ( mean age 51.7 yrs ; disease duration 10.2 yrs ) and 120
patients with
FM ( mean age 50.2 yrs ; disease duration 5.6 yrs ) were evaluated . -
pubmed
Univariate analysis showed that
patients with
FM had higher mean tender point and
enthesitis scores , more
somatic symptoms , and responded less to NSAID . -
pubmed
This research was carried out to investigate if
zerumbone , a natural
cyclic sesquiterpene isolated from
Zingiber zerumbet Smith , will produce the anticancer effects on
pancreatic carcinoma cell lines . -
pubmed
Genome sequence of
erythromelalgia - related poxvirus identifies it as an
ectromelia virus strain . -
pubmed
An epidemic form of this
syndrome occurs in secondary students in rural China and a virus referred to as
erythromelalgia - associated poxvirus (
ERPV ) was reported to have been recovered from throat swabs in 1987 . -
pubmed
Studies performed at the time suggested that
ERPV belongs to the orthopoxvirus genus and has similarities with
ectromelia virus , the causative agent of
mousepox . -
pubmed
We have determined the complete genome sequence of
ERPV and demonstrated that it has 99.8 % identity to the Naval
strain of
ectromelia virus and a slighly lower identity to the Moscow
strain . -
pubmed
Small DNA deletions in the Naval genome that are absent from ERPV may suggest that the sequenced
strain of Naval was not the immediate progenitor of
ERPV . -
pubmed
MATERIALS AND METHODS : Between January 2006 and December 2009 a functional assessment of 15
patients ( 10
males and 5
females ) who had undergone ankle arthrodesis for
posttraumatic arthritis and/or
avascular necrosis (
AVN ) talus ( n=6 ) ,
malunited bimalleolar fracture ( n=4 ) , distal
tibial plafond fractures ( n=3 ) ,
medial malleoli nonunion ( n=2 ) . -
pubmed
RESULTS : All
patients had sound
ankylosis and no complications related to the surgery . -
pubmed
CONCLUSION : Spectral domain OCT is a valuable imaging technology enabling detailed visualization of retinal changes in
patients with
CSC . -
pubmed
Hemodialysis does not affect
everolimus pharmacokinetics : two cases of
patients with
metastatic renal cell cancer . -
pubmed
Assessment of cerebrovascular reactivity using real - time BOLD fMRI in
children with
moyamoya disease : a pilot study . -
pubmed
PURPOSE : This pilot study aims to test the reliability and clinical validity of the assessment of cerebrovascular reactivity ( CVR ) with real - time blood -
oxygen - level - dependent ( BOLD ) fMRI ( rtCVR ) in comparison with standard off - line processing in
children with
moyamoya disease . -
pubmed
CONCLUSIONS : rtCVR assessment in
children with
moyamoya disease is feasible , and the results are comparable to that of standard off - line analysis . -
pubmed
METHODS : We reviewed the literature dealing with
altered mental status or
seizures in enuretic
subjects on
desmopressin . -
pubmed
The retained publications included
patients who were described individually , revealing data on mode of administration , further identifiable factors predisposing to
hyponatremia , presentation and clinical course . -
pubmed
We developed an F1
mouse host embryo ( Perfect Host , PH ) that selectively ablates its own germ cells via tissue - specific induction of
diphtheria toxin . -
pubmed
Neurological disease in
lambs associated with exposure to high environmental temperature and humidity . -
pubmed
BACKGROUND : We detected a pattern of
lambs presenting with
hyperthermia and neurological signs during the summer . -
pubmed
ANIMALS : Fifteen clinical cases of
lambs less than 12 months of age presenting with neurological signs ,
tachypnea , and
hyperthermia over 4 summers . -
pubmed
Medical records were searched for
lambs less than 12 months of age that presented with neurological signs including the following :
kyphosis ,
pelvic limb hyperextension ,
treading of feet ,
muscle tremors and
recumbency , and
hyperthermia of greater than 104 F. A grading system was established to describe severity of presenting neurological signs . -
pubmed
Eighteen female
patients with a diagnosis of
BPD and 18 healthy control subjects anticipated cued visual stimuli with prior known emotional valence or prior unknown emotional content during functional magnetic resonance imaging . -
pubmed
DESIGN : Seventy - nine ( 79 )
children , aged 8 - 16 years , were studied and divided into four groups : 19 control (
BMI z - score range -2.15 - 1.24 ) , 20
overweight ( 1.34 - 2.49 ) , 20
obese ( 2.50 - 2.87 ) and 20 ultra -
obese ( 3 - 4.37 ) . -
pubmed
In
patients with
congenital heart disease , cardiac MRI is established as a valuable diagnostic tool in daily clinical management , especially for the evaluation of
pulmonary valve defects . -
pubmed
METHODS AND RESULTS : Excluding medication used in
atrial fibrillation , we matched
individuals on ACEi monotherapy 1:1 with
individuals on beta - blocker ( n = 48 658 ) ,
diuretic ( n = 69 630 ) ,
calcium - antagonist ( n = 57 646 ) , and ARB monotherapy ( n = 20 158 ) . -
pubmed
Identification and validation of novel candidate protein biomarkers for the detection of
human gastric cancer . -
pubmed
By combining a validated preclinical
mouse model with a proteomic approach we have recently discovered novel biomarkers for the detection of
gastric cancer . -
pubmed
Eighty
patients with isolated
SVT of the legs were instructed to wear compression stockings ( 23 - 32 mmHg ) ( CG ) or no compression ( NCG ) for 3 weeks . -
pubmed
At day 7 ,
patients in the CG revealed a significantly faster
thrombus regression ( p = .02 ) . -
pubmed
Aprocta cylindrica ( Nematoda ) infection in a
European Robin (
Erithacus rubecula ) in Britain . -
pubmed
A
European Robin (
Erithacus rubecula ) found dead in England had marked
blepharitis and
periocular alopecia associated with
Aprocta cylindrica ( Nematoda : Aproctidae ) and concurrent mixed
fungal infections . -
pubmed
Aprocta cylindrica should be considered a differential diagnosis in
periocular abnormalities of robins and other insectivorous , migratory passerines in Western Europe . -
pubmed
Serum galactomannan - based early detection of invasive
aspergillosis in hematology
patients receiving effective antimold prophylaxis . -
pubmed
BACKGROUND : There is a practical need to investigate the performance of the serum galactomannan ( GM ) assay in hematology
patients with a potentially low pretest risk of invasive
aspergillosis following effective antimold prophylaxis . -
pubmed
METHODS : We measured
frailty ( shrinking ,
weakness , exhaustion , low physical activity , and slowed walking speed ) , other
patient and donor characteristics , longitudinal MMF doses , and graft loss in 525 kidney transplantation recipients . -
pubmed
To address this , the responses of two
strains of the model
brown alga Ectocarpus siliculosus isolated from sites with different histories of metal contamination exposed to total
copper (
CuT ) concentrations ranging between 0 and 2.4 muM for 10 days were investigated . -
pubmed
parvum ( odds ratio [ OR ] = 2.6 ; 95 % confidence interval [ CI ] , 1.3 - 5.6 ; P = 0.02 ) ,
BRV ( OR = 2.7 ; 95 % CI , 1.3 - 5.9 ; P = 0.01 ) and co -
infection with more than one agent ( compared with mono -
infection : OR = 2.5 ; 95 % CI , 1.3 - 4.8 ; P = 0.01 ) were associated with increased odds of liquid faeces in calves which were 9 to 21 days old . -
pubmed
Vaccinating
cows against calf enteropathogens ( OR = 0.2 ; 95 % CI , 0.1 - 0.9 ; P = 0.03 ) , administering waste milk ( from
mastitis and/or containing antibiotics ; OR = 0.4 ; 95 % CI , 0.1 - 0.8 ; P = 0.01 ) , the sex of calves ( females compared to males OR = 0.2 , 95 % CI , 0.07 - 0.7 ; P & lt;0.01 ) , and the use of straw for bedding ( OR = 0.2 ; 95 % CI , 0.03 - 0.9 ; P = 0.03 ) decreased the odds of liquid faeces . -
pubmed
METHODS : In vivo studies , 50 mul PBS or 1.5x10(6)(Norm)BMSCs , ( GFP)BMSCs or ( CREG)BMSCs were implanted intramyocardially in
myocardial infarction rat models . -
pubmed
BACKGROUND : In
patients with
degenerative meniscal tears , subclinical
cartilage degeneration may be present even if gross morphological changes are not evident . -
pubmed
The aim of this study was to detect occult
cartilage degeneration using T1rho MRI mapping in
patients with
meniscal tears without obvious radiographic
osteoarthritis (
OA ) . -
pubmed
Measuring
glomerular filtration rate by
iohexol clearance on filter paper is feasible in
adolescents with
type 1 diabetes in the ambulatory setting . -
pubmed
Testing 24
women with
androgenetic alopecia has demonstrated a positive effect of mesotherapy on the hair growth , hair thickness , with only insignificant increase of hair density . -
pubmed
This randomized , double - blind controlled study evaluated the effects of a single 100 - mg oral dose of
ABT-639 , compared with placebo , on abnormal spontaneous activity in peripheral C - nociceptors , measured for the first time by microneurography in adult
patients with painful
diabetic neuropathy . -
pubmed
The utilization of microneurography as a means to measure abnormal activity in C - nociceptors in
human clinical studies opens new possibilities for future studies of compounds targeting
peripheral nerve hyperexcitability . -
pubmed
Duck virus enteritis , also known as duck
plague , is an acute
herpes viral infection of ducks caused by
duck enteritis virus (
DEV ) . -
pubmed
The method of repeated immunization with a live attenuated vaccine has been used for the prevention and control of
duck enteritis virus (
DEV ) . -
pubmed
We thus propose an emotional model of
ASD that adapts a Bayesian model of the uncanny valley effect , which holds that a
human - looking robot can provoke repulsion and sensations of eeriness . -
pubmed
Consequently , individuals with
ASD may find it more comfortable , and may modify their emotional response , if the robots look like deformed
humans , even if they appear " creepy " to typical individuals . -
pubmed
Therefore , we suggest that our model explains the effects of robot - assisted therapy in children with
ASD and that
human - looking robots may have potential advantages for improving social interactions in
ASD . -
pubmed
The aims of this study is to compare the growth and
glucose metabolism of three
Lactobacillus reuteri strains ( i.e. -
pubmed
It was also shown that , in the context of obtaining a large amount of biomass ,
DSM 20016 and
DSM 17938 strains were the most effective in terms of growth kinetics . -
pubmed
MATERIALS AND METHODS : We identified 422
patients who met National Comprehensive Cancer Network very low ( 199 ) and low risk ( 223 )
prostate cancer definitions who instead underwent radical prostatectomy . -
pubmed
Prolonged Support Using a Percutaneous OxyRVAD in a
Patient with
End - Stage Lung Disease ,
Pulmonary Hypertension , and Right
Cardiac Failure . -
pubmed
Options for cardiopulmonary support in
patients with severe
pulmonary hypertension (
PH ) that is not associated with left - sided
heart failure are limited . -
pubmed
We describe the novel use of prolonged percutaneous venovenous extracorporeal membrane oxygenation as a right ventricular assist device in a
patient presenting with
cardiogenic shock because of severe
PH decompensation . -
pubmed
METHODS : The medical records of
patients with
ovarian CCC who had undergone primary staging surgery or cytoreductive surgery followed by systemic chemotherapy were retrospectively reviewed . -
pubmed
Using a more clinically relevant sample , we extracted and amplified
Plasmodium falciparum DNA from
malaria - infected
human blood cultures . -
pubmed
Approximately half of
patients with
coronary spastic angina had pathologic exercise tests . -
pubmed
Organic stenosis ( & gt;75 % ) was observed in 44
patients . -
pubmed
Multiple
spasms were recognized in 204
patients ( 68 % ) . -
pubmed
Positive response was significantly higher in
patients with
organic stenosis than those without fixed
stenosis ( 63.6 % vs. 33.2 % , p<0.001 ) . -
pubmed
Moreover , ST elevation was more frequent in
patients with
organic stenosis than those without fixed
stenosis ( 27.3 % vs. 1.2 % , p<0.001 ) . -
pubmed
Positive response in
patients with
effort angina ( 46.8 % ) was higher than those in patients with
rest angina ( 33.6 % ) and rest and
effort angina ( 36.6 % ) , but not significant . -
pubmed
CONCLUSIONS : TET was useful in documenting
ischemia in
patients with
CSA . -
pubmed
Moreover , we obtained the pathologic TET response in approximately half of
patients with
CSA . -
pubmed
Pulmonary Embolism in a 3 - Year - Old
Boy with
Nephrotic Syndrome . -
pubmed
We present the case of a 3 - year - old
boy with
nephrotic syndrome with mild
respiratory symptoms who was shown by ventilation - perfusion scan to have
pulmonary embolism . -
pubmed
Onychomycosis caused by
Aspergillus terreus . -
pubmed
Between 1993 and 2011 , 107
patients with
intracranial meningiomas involving MVS underwent surgery in our institution . -
pubmed
Interestingly , there was no progression in
patients that underwent radiation therapy or gamma knife radiosurgery for residual
tumor . -
pubmed
Overall , 5.2 % of urine isolates were
ESBL and 9.5 % isolates with
pyuria ( & gt;100x106 WC / L ) had ESBL , whereas only 22/1032 ( 2.1 % ) with no
pyuria , ( P<0.0001 ) . -
pubmed
It has formed the basis for the setting up of
leg ulcer clinics in the community , the principles of patient assessment , and the use of four - layer bandages as the first - line treatment for
patients with venous and mixed disease . -
pubmed
This study sought to evaluate differences in nocturnal wakefulness in
depressed individuals who did and did not have an antisuicidal response to
ketamine . -
pubmed
Vaccination of
alpacas against
Rift Valley fever virus : Safety , immunogenicity and pathogenicity of MP-12 vaccine . -
pubmed
Previous outbreaks attributed camelids a significant role in the epidemiology of
Rift Valley fever virus (
RVFV ) , making them an important target species for vaccination . -
pubmed
Viral replication was confirmed by detection of various
RVFV - antigens in hepatocytes by immunohistochemistry and the presence of mild multifocal
necrotizing hepatitis . -
pubmed
OBJECTIVE : To identify the predictors of
RCD , in a population of community - dwelling
patients with recently diagnosed late onset
AD . -
pubmed
All
patients underwent a standardized clinical
dementia investigation . -
pubmed
Lymph Drainage During
Wound Healing in a
Hindlimb Lymphedema Mouse Model . -
pubmed
CONCLUSIONS : In a hindlimb
lymphedema mouse model , lymph transiently accumulated in subcutaneous tissue , and then was gradually absorbed by the existing lymph vessels . -
pubmed
Among the various
enteric diseases ,
necrotic enteritis (
NE ) is an
enterotoxemic disease caused by
Clostridium perfringens , which can result in severe economic losses in poultry farming . -
pubmed
Bacillus subtilis PB6 was reported to prevent
necrotic enteritis and improve performance in birds . -
pubmed
Bacillus subtilis PB6 significantly ( P & lt ; 0.05 ) improved
body weight and FCR ( 8 points ) compared to the control . -
pubmed
A total of 145
PsA patients were included in the study . -
pubmed
Nine
patients ( 6.2 % ) reported the onset of mild
infections resolved with antimicrobial specific oral regimen without therapy interruption . -
pubmed
Treatment - related mortality ( TRM ) remains elevated in adult
patients undergoing umbilical cord blood transplantation ( UCBT ) , including an early rise in TRM suggestive of excessive
toxicity associated with the standard myeloablative total body irradiation ( TBI ) ,
fludarabine , and
cyclophosphamide regimen . -
pubmed
Thirty - one adult
patients ( median age , 46 years ; range , 19 to 65 ) with
hematologic malignancies (
acute leukemia /
myelodysplastic syndrome , 77 % ;
lymphoid malignancy , 23 % ) underwent single ( n = 1 ) or double ( n = 30 ) UCBT from 2010 to 2015 at our institution . -
pubmed
The overall incidence of chronic
GVHD at 2 years was 40 % ( 95 % CI , 22 % to 57 % ) , with 17 % of
patients ( 95 % CI , 6 % to 33 % ) experiencing moderate to severe chronic
GVHD by 2 years . -
pubmed
The fungal
strains were identified and registered at NCBI as
Aspergillus niger asemoA ( KY473958.1 ) ,
Talaromyces purpurogenus asemoF ( KY488463.1 ) ,
Trichoderma harzianum asemoJ ( KY488466.1 ) and
Aspergillus flavus asemoM ( KY488467.1 ) . -
pubmed
BACKGROUND : The resistance of some medico - veterinary parasite
strains as well as the unavailability and
toxicity of synthetic anthelminthics on
humans , animals and the impacts of their residues in the environment have pushed scientists to turn to plants with anthelminthic properties . -
pubmed
Patients supported by LVADs were more likely to be supported longer ( p = 0.003 ) , have a higher
death by cardiac event ( p = 0.013 ) and retransplantation rate ( p = 0.015 ) . -
pubmed
Anti -
tumor effects of the
American cockroach ,
Periplaneta americana . -
pubmed
Since the incidence of
cancer has been on the rise due to increasing exposure to various carcinogenic factors in recent years ,
cancer has gradually become the first killer to the health of
human beings . -
pubmed
In this review , the research progress on the anti -
tumor effects of
P. - pubmed
This review aims to provide an overview of the research on anti -
tumor effects of
P. - pubmed
Many
strains of
zebrafish (
Danio rerio ) are readily available . -
pubmed
The latter finding adds to the growing database of phenotypical differences between
zebrafish of the AB and TL
strain . -
pubmed
Methods : Ninety - two
patients with stage III
NSCLC were analyzed retrospectively based on treatment given . -
pubmed
Conclusions :
Patients with stage IIIA and , perhaps IIIB
NSCLC with a high performance status should be considered for trimodality treatment . -
pubmed
The aim of the present study was to investigate the effects of carboxymethyl cellulose ( CMC ) and chitosan ( CH ) coatings containing
Mentha spicata essential oil ( MSO 0.1 and 0.2 % ) on survival of
Listeria monocytogenes , and physicochemical (
weight loss , titratable acidity and pH ) , microbial ( total viable count , psychrotrophic bacteria as well as yeasts and molds ) and sensory ( appearance , color , texture and overall acceptability ) properties of fresh
strawberries during refrigerated storage . -
pubmed
MATERIALS AND METHODS : Fifty - three
patients with advanced lower
rectal cancer were examined before and after neoadjuvant chemoradiotherapy with use of TRUS plus UE and CEUS and were diagnosed as having T stage disease . -
pubmed
RESULTS : For
patients with rectal
cancer , ultrasonic T stages were lower after neoadjuvant chemoradiotherapy than before , with a statistically significant difference ( P & lt ; 0.05 ) . -
pubmed
A battery of toxicological studies was conducted in accordance with international guidelines to investigate the
genotoxicity and repeated - dose
oral toxicity in
rats of synthetic
curcumin (
VEAMIN 99 , & gt;99 % purity ) . -
pubmed
There was no evidence of mutagenicity in a
bacterial reverse mutation test , whereas an in vitro
mammalian chromosomal aberration test was positive for induction of
chromosomal aberrations which is in line with results reported for natural
curcumin . -
pubmed
There was no evidence of
genotoxicity in an in vivo
mammalian micronucleus test . -
pubmed
Association of tibial plateau leveling osteotomy with proximal tibial
osteosarcoma in
dogs . -
pubmed
OBJECTIVE To assess for any association between a history of tibial plateau leveling osteotomy ( TPLO ) and subsequent development of proximal tibial
osteosarcoma in
dogs . -
pubmed
ANIMALS 34 client - owned
dogs in which proximal tibial
osteosarcoma was diagnosed between January 2005 and December 2012 ( cases ) and 79
dogs without
osteosarcoma , matched 3:1 to cases ( when possible ) by age , breed , and initial examination date ( controls ) . -
pubmed
A multivariable conditional logistic regression model was constructed to evaluate associations of
body weight and history of TPLO with the outcome of proximal tibial
osteosarcoma in
dogs . -
pubmed
RESULTS After adjusting for
body weight in the multivariable model ,
dogs with a history of TPLO were 40 times as likely to develop proximal tibial
osteosarcoma as were
dogs with no history of TPLO . -
pubmed
CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that
dogs with a history of TPLO were at increased risk of developing
osteosarcoma of the proximal region of the tibia relative to
dogs with no such history . -
pubmed
Therefore , it is important for proximal tibial
osteosarcoma to be included among the differential diagnoses for new or worsening
hind limb lameness in
dogs that underwent TPLO & gt;= 1 year previously . -
pubmed
This phenomenon can also be observed in
mycobacterial and fungal infections that produce
granulomas in infected
patients . -
pubmed
Patients are often diagnosed with
fractures ,
dislocations ,
bursitis , and
muscle strain . -
pubmed
To enhance its efficacy , a combinational study of
selenium yeast ( SY ) and
fish oil ( FO ) was performed in
A549 ,
CL1 - 0 ,
H1299 ,
HCC827 lung adenocarcinoma ( LADC ) cells to investigate the enhancement in apoptosis induction and underlying mechanism . -
pubmed
The primary efficacy endpoint was to demonstrate the superiority and higher accuracy of FD - OCT compared to 2D - QCA in evaluating
stenosis severity in
patients with ICL . -
pubmed
Methods : A cohort of
patients suffering from
GCTTS of the hand and treated surgically were studied in terms of diagnosis , therapy ,
recurrence , as well as in terms of functional outcome with the use of the QuickDASH score . -
pubmed
Prognosis and risk stratification in
patients with decompensated
heart failure receiving inotropic therapy . -
pubmed
Methods : We analysed a prospective cohort of adult
patients admitted with decompensated
HF and ejection fraction ( left ventricular ejection fraction ( LVEF ) ) less than 50 % . -
pubmed
Main aetiologies were
dilated cardiomyopathy in 273 ( 37.0 % ) patients ,
ischaemic heart disease in 195 ( 26.5 % ) patients and
Chagas disease in 163 ( 22.1 % )
patients . -
pubmed
PURPOSE : To describe the clinical and histopathologic features secondary to
ocular and periocular snakebites in
dogs requiring enucleation . -
pubmed
METHODS : Retrospective review of
patients with recorded
snakebite envenomation from the archives of the Comparative Ocular Pathology Laboratory of Wisconsin ( COPLOW ) and Texas A&M Veterinary Medical Teaching Hospital ( 1997 - 2017 ) . -
pubmed
The cases included in this study required witnessed
snakebites to the
dog by the owner , clinical signs supportive of
periocular or ocular envenomation , and/or histopathologic lesions compatible with
snakebites . -
pubmed
As in
humans and
horses , studying
inflammation of the deep airways by lung cytology raises the possibility of preventing
respiratory disease and targeting its treatment in the future . -
pubmed
Mean BALf neutrophil percentage was 36.6 % ( SD 23.8 ; R 0 - 97.4 ) and only a positive induced
tracheal cough reflex ( P = 0.04 ) , standing posture ( P = 0.03 ) increased breathing rate ( P = 0.02 ) and isolation of
Pasteurella multocida ( P = 0.005 ) , were associated with increased neutrophil percentage . -
pubmed
PURPOSE : As a conserved cellular stress response , autophagy has recently been demonstrated to be involved in the pathogenesis of several
human cancers . -
pubmed
METHODS : A total of 83
patients with primary
HCC were enrolled in this study . -
pubmed
In this review , we discuss the burden of
bleeding in anticoagulated
patients and the need for reversal agents , review the mechanism of action of
andexanet and critically evaluate the evidence for its efficacy and safety . -
pubmed
Breast cancer is one of the most
human malignant diseases and the leading cause of
cancer - related
death in the world . -
pubmed
Based on these results , we can conclude that this immune score may be a useful tool for overall survival prediction and treatment guidance for
patients with
breast cancer . -
pubmed
Impact of adjuvant therapy in
patients with invasive
intraductal papillary mucinous neoplasms of the pancreas . -
pubmed
BACKGROUND : There is limited data on the efficacy of adjuvant therapy ( AT ) in
patients with invasive
intraductal papillary mucinous neoplasms of the pancreas (
IPMN ) . -
pubmed
This single center retrospective cohort study aims to assess the impact of
AT on survival in these
patients . -
pubmed
METHODS :
Patients undergoing surgery for invasive
IPMN between 1993 and 2018 were included in the study . -
pubmed
Patients in the
AT group were significantly younger , presented at higher T and N stages and had more perineural and lymphovascular invasion . -
pubmed
N0
patients have excellent survival , and
AT should probably be avoided in them , whereas it may be considered in
patients with N+ disease . -
pubmed
Sulfated
vizantin showed no
cytotoxicity against the
human gingival cell line
Ca9 - 22 . -
pubmed
PARTICIPANTS :
Patients diagnosed with
acute ischemic stroke , January 1 , 2011 - May 31 , 2017 . -
pubmed
PARTICIPANTS : A total of 71 934 post-9/11
Veterans with
mTBI from the Chronic Effects of
Neurotrauma Consortium Epidemiology warfighter cohort . -
pubmed
Method Sample consisted of 59
tinnitus patients who reported stable
tinnitus . -
pubmed
BACKGROUND : Survival rates in
patients with
esophageal cancer undergoing esophagectomy have improved , but the prevalence of
gastric tube cancer (
GTC ) has also increased . -
pubmed
Total resection of the gastric tube with lymph node dissection is considered a radical treatment , but GTC surgery is more invasive and involves a higher risk of severe complications or
death , particularly in elderly
patients . -
pubmed
CASE SUMMARY : We report an elderly
patient with early
GTC that had invaded the duodenum who was successfully treated with resection of the distal gastric tube and Roux - en - Y ( R - Y ) reconstruction . -
pubmed
A 47 - year - old
woman was diagnosed with
PSC . -
pubmed
ICH and normal specimens were obtained from the tissue adjacent to and distant from
hematoma of
ICH patients , respectively . -
pubmed
There were under observation 440
patients with
ischemic heart disease due to
atherosclerosis of the coronary arteries in the phase of exacerbation of the disease and 52
patients suffering from
hypertensive disease with a clinical picture of
ischemic heart disease ; 192 practically healthy
individuals were examined as controls . -
pubmed
Significant increase in the levels of
cholesterol ,
triglycerides , and
glucose in blood of the
patients with
ischemic heart disease and of those with
hypertensive disease was revealed . -
pubmed
In
patients with
ischemic heart disease marked by
pain and
disorders of the rhythm as well as in individuals with
hypertensive disease hormonal - metabolic shifts , monotypical in character , were noted . -
pubmed
Utilizing antibarbiturate serum in an indirect immunofluorescence system ,
phenobarbital has been detected in the central nervous system of
mice given an
overdose of drugs . -
pubmed
The use of non -
human primates for production of antisera to
human tumor - associated antigens . -
pubmed
High - titered antisera against
human melanoma- and
leukemia - associated antigens have been produced in non -
human primates . -
pubmed
The data from this and from other studies suggest that this model may prove a valuable source of highly specific antisera against a variety of
human tumor - associated antigens or alloantigens . -
pubmed
In male
mice and
rats , one drop of an extract from
Dryopteris filix mas , administered orally pure or suspended in
sunflower - seed oil , caused a spectacular
enlargement of the penis . -
pubmed
From these observations and a review of the pertinent literature , we conclude that the
patients described in this report have an
organic deficiency of brain function , determined congenitally or in the early postnatal period . -
pubmed
This article reports on the treatment of 21
obesity patients employing auricular acupuncture . -
pubmed
It seems probable that the blood of goslings has a smaller
oxygen carrying capability that that of the
chicken and this might be reflected with their slower metabolic rate per
body weight unit . -
pubmed
Cryopreserved autologous platelet transfusions in alloimmunized
patients with
acute leukemia . -
pubmed
Autologous platelets of 5 alloimmunized
patients with
acute leukemia in remission were cryopreserved with 5 %
dimethylsulfoxide in liquid
nitrogen and retransfused in the following therapy - induced
thrombocytopenic phase . -
pubmed
To evaluate the spectrum of
coronary artery disease (
CAD ) in
cocaine users , coronary angiograms obtained from 33
patients ( 26
men [ 79 % ] and 7 women [ 21 % ] , mean age 37 years ) with history of
cocaine use and cardiac symptoms were retrospectively reviewed . -
pubmed
Thirteen
patients ( 40 % ) had normal coronary angiograms , and 20 ( 60 % ) had
CAD ; 7 ( 21 % ) had mild
CAD ( less than or equal to 70 % diameter
stenosis ) , and 13 ( 40 % ) had significant
CAD ( greater than 70 % diameter
stenosis ) . -
pubmed
Of 13
patients with significant
CAD , 7 had 1 - vessel , 4 had 2 - vessel and 2 had 3 - vessel
CAD . -
pubmed
There was enzymatic evidence of
myocardial infarction in 12 of 33
patients ( 36 % ) ; all 12 had
CAD ( 10 with significant and 2 with mild
CAD ) . -
pubmed
Mean age and number of risk factors ( serum total
cholesterol , cigarette smoking ,
systemic hypertension ,
diabetes mellitus , family history of
CAD , and
obesity ) in
patients with
CAD ( mild or significant ) and with normal coronary angiograms were not statistically different . -
pubmed
All
patients with
CAD and low ejection fractions ( n = 12 ) had regional wall motion abnormalities , whereas all those with normal coronary arteries and low ejection fraction ( n = 6 ) had global
hypokinesia . -
pubmed
The correction of
ARF was achieved in 85 % of the
patients with a mask of
O2 less than 40 % . -
pubmed
The results suggest that NMR imaging is effective for assessing the results of initial palliative surgery for
hypoplastic left heart syndrome , which seems to be important for managing
patients before subsequent definitive surgery . -
pubmed
In
human atherosclerotic lesions , many of the macrophage foam cells also contain ceroid , an insoluble polymer formed by oxidation of mixtures of lipid and protein . -
pubmed
In this study , the diagnostic value of a new tracer :
99mTc - methoxy - isobutyl - isonitrile (
MIBI ) has been demonstrated in
patients with
leg claudication . -
pubmed
We successively performed muscle perfusion scans in 6
normals and 18
patients with
claudication pain during rest and after exercise on the same day . -
pubmed
Muscle perfusion abnormalities in all
patients were consistent with the defects in the arteries of the affected limbs . -
pubmed
Propofol in combination with
fentanyl diminished mean arterial pressure ( -28.7 % ) and heart rate ( -17.3 % ) when used for induction in
patients with
ischemic heart disease , even in low doses and with slow administration . -
pubmed
There was no evidence of non - homogeneous tissue perfusion as assessed by increases in
lactate concentration ,
cardiac ischemia , or
liver dysfunction in any of the
patients . -
pubmed
There were no
postoperative complications in either group , but the
return of consciousness , adequate spontaneous ventilation , and psychomotor activity was more rapid in the
propofol patients . -
pubmed
However , the use of
propofolfentanyl for induction of anesthesia in
patients with limited coronary perfusion is not recommended because of its
hypotensive effect . -
pubmed
In the present study we compared the binding characteristics of peripheral
benzodiazepine - binding sites in
human epithelial ovarian carcinoma with those in benign
ovarian tumours and normal ovaries . -
pubmed
Patients who were thought to be at high risk for
postoperative ileus had a Foley catheter inserted intraoperatively through the greater curvature of the stomach . -
pubmed
The procedure was found to be technically easy , well tolerated by the
patients , and clinically useful , since postsurgical
ileus was prevented or treated without the local and respiratory ill effects of the commonly used nasogastric tube . -
pubmed
Toxicity of
FK-506 in
human fetal pancreas . -
pubmed
Our results suggest that further work with FK will show that this immunosuppressive agent can be used with HFP transplantation into
diabetic patients without toxicity to HFP . -
pubmed
Using a lead exposure model considered to represent subclinical lead
toxicity in
man , it was shown that perinatal lead exposure disrupts opioid but not non - opioid mediated stress antinociception . -
pubmed
As reported previously , the peculiar intracytoplasmic eosinophilic inclusion bodies ( IEIBs ) extensively appeared in the autopsied brain tissue from a 49 - year - old
man having
familial ataxia with
cerebrospinal fluid abnormality , and histochemically showed abundant proteins , but few lipids and
carbohydrates . -
pubmed
Cauliflower growths in
ulcers of
leprosy -- a question of
malignancy . -
pubmed
Systemic activation of the coagulation mechanism is known to exist in
patients with
colon cancer . -
pubmed
N -( 2 - hydroxypropyl ) methacrylamide polymeric prodrugs containing
adriamycin bound to polymers via
glycylphenylalanylleucylglycine side chains and , in one case ,
galactosamine bound via the same sequence , were tested for immunogenicity after intravenous , subcutaneous and oral application in two inbred
strains of
mice . -
pubmed
Achieving oral health in
patients with
renal failure and renal transplants . -
pubmed
The protocols for oral evaluation and treatment of
patients with
renal failure and renal transplants are presented . -
pubmed
Local cerebral metabolic rate for
glucose ( LCMRglc ) was measured with positron emission tomography using the
18F - fluorodeoxy - glucose method in five
patients with
chorea due to different underlying diseases . -
pubmed
Hypometabolism was observed in the striatum bilaterally in
patients with
Huntington ' s disease ,
choreoacanthocytosis ,
sporadic progressive chorea and
dementia , and pseudo - Huntington form of
dentato - rubro - pallido - luysian atrophy (
DRPLA ) . -
pubmed
The
patient with
hemichorea showed hypometabolism in the striatum on the contralateral side to the
chorea . -
pubmed
The
patient with pseudo - Huntington form of
DRPLA showed a diffusely decreased LCMRglc in other structures including the cerebral cortex , thalamus and cerebellum . -
pubmed
These findings indicated that
dysfunction of the striatum is relevant to the genesis of
chorea in all these
patients , even though the extent of dysfunction in other structures is different in each case . -
pubmed
Somatosensory - evoked potential study in
headache patients . -
pubmed
Somatosensory - evoked potentials ( SEPs ) after median nerve stimulation were studied in 34
patients with common
migraine , in 30
patients with
muscle - contraction headache , and in 10
cluster headache patients . -
pubmed
No changes were observed in muscle - contraction
headache patients either with or without
histamine administration . -
pubmed
In these 10
patients , 9 were
hypertensive , and the signs characteristics of parenchymal
hemorrhage , e.g. -
pubmed
Seven
patients with non advanced
cancer of the lower third of the rectum underwent sphincter - saving resection through a combined abdominoperineal approach . -
pubmed
The mean follow - up is 8 months and all
patients are free of
recurrence and continent . -
pubmed
A total of 433 extracorporeal lithotripsy procedures was performed for
renal , ureteral and bladder stones by means of a system of ultrasonographic detection and piezoelectric destruction in 386
patients . -
pubmed
Of the 217
patients with a
renal stone reviewed at 3 months 161 ( 74 per cent ) had successful results and 56 ( 26 per cent ) failed therapy . -
pubmed
The morbidity was low : 2 per cent of the
patients suffered
ureteral obstruction , 1.5 per cent had subcapsular
hematoma and 4 per cent had
fever . -
pubmed
The use of sublingual
nifedipine in a
patient with a
clonidine overdose . -
pubmed
The sensitivity to lipolytic agents is altered in
diabetic vs. control
animals . -
pubmed
Rats , rendered
diabetic by
STZ ( 65 mg / kg ) , were used on day 3 . -
pubmed
Aluminum - associated
osteomalacia and transfusion - induced
hemosiderosis developed in an
anephric patient receiving long - term maintenance treatment with continuous ambulatory peritoneal dialysis . -
pubmed
We have used groin flaps to cover deep hand
burn defects in nine
patients . -
pubmed
A series of
nitroheterocyclic compounds with antimicrobial and radiosensitizing properties was tested for
embryotoxicity in cultured
Sprague - Dawley rat embryos , and their effects were compared with various other five - membered
heterocycles . -
pubmed
The
dermatitis of 9 of the
patients had flared after open oral challenge with balsam of Peru , and the
dermatitis of 31
patients had flared after double - blind oral challenge . -
pubmed
The AoE index ( AoE corrected for body surface area ) in
patients with
ASD was significantly greater than in disease - free subjects ( 0.81 vs 0.59 cm , p less than 0.01 ) . -
pubmed
[
Vitamin A deficiency in
piglets with
seborrheic eczema ] . -
pubmed
Depression of humoral antibody formation in the
chicken by thymectomy and antilymphocyte serum . -
pubmed
The induction of
leukemia and life shortening in
mice by continuous low - level external gamma radiation . -
pubmed
Extended long term physical training regimes can induce chronic modifications of cardiac function in both healthy
individuals and subjects with
coronary artery disease . -
pubmed
The
human hepatoma cell line
PLC / PRF / 5 produces
tumours and
lung metastases in
nude athymic mice . -
pubmed
Antigens soluble in hot
trichloracetic acid from eighteen
strains of
Pityrosporum ovale were studied using
rabbit antiserum to American Type Culture Collection strains 24027 , 12078 , and 14521 . -
pubmed
These
strains were found to share two antigens , both of which were present in cells of
Pityrosporum orbiculare and one of which was present in cells of
Pityrosporum pachydermatis ,
Pityrosporum canus ,
Candida albicans and
Rhodotorula rubrum . -
pubmed
The paraclinical findings of 7
patients with
distal renal tubular acidosis and
nephrolithiasis and
nephrocalcinosis , respectively , are discussed . -
pubmed
We show that this '
retroviral lox system ' allows the
infection of cells and the expression of transferred genes . -
pubmed
High - dose
doxorubicin ,
etoposide , and
cyclophosphamide with stem cell reinfusion in
patients with metastatic or high - risk primary
breast cancer . -
pubmed
Recent data suggest that selected groups of
patients with metastatic
disease treated with high - dose chemotherapy and stem cell support may enjoy unmaintained , long - term remission . -
pubmed
This study was designed to establish the feasibility of administering the combination of high - dose infusional
doxorubicin ,
etoposide , and
cyclophosphamide followed by autologous stem cell rescue in
patients with responsive metastatic , or high - risk primary
breast cancer . -
pubmed
Two
patients suffered grade 3
mucositis at the highest level of
doxorubicin ( 200 mg / m2 ) . -
pubmed
Of 21
patients treated for primary high - risk
breast cancer , 19 are
recurrence free , with a median follow - up of more than 8 months ( & gt ; or = 4 - 36 months ) . -
pubmed
The diverse nature of the mutants isolated from
L5178Y cells suggests that the
mouse -
lymphoma mutagenesis assay is capable of detecting a number of mutation types , enhancing the utility of the assay in studying the range of
genetic lesions important in
human disease . -
pubmed
Myocardial
cyclic AMP and
norepinephrine content in
human heart failure . -
pubmed
Impaired production of myocardial
cyclic adenosine monophosphate (
cAMP ) is thought to contribute to
contractile dysfunction in end stage
heart failure , but myocardial
cAMP content has not yet been evaluated in
heart failure patients in comparison with controls . -
pubmed
We therefore measured the myocardial content of
cAMP by radioimmunoassay in endomyocardial biopsies from
patients in different stages of
heart failure and in controls and correlated it with biochemical and functional parameters . -
pubmed
Plasma
cAMP in 20
heart failure patients ( 22.0 + /- 4.2 pmol.l-1 ) was not different from controls(22.0 + /- 7.8 ) , whereas plasma
norepinephrine was increased (
heart failure : 460 + /- 257 pg.ml-1 , controls 182 + /- 49 , P & lt ; 0.001 ) . -
pubmed
Myocardial
cAMP levels are indistinguishable from controls in
human heart failure and therefore do not contribute to a further characterization of the cardiac adrenergic system in these
patients . -
pubmed
Lytic
infection of
Escherichia coli biofilms by bacteriophage T4 . -
pubmed
Early
ischemic injury leads to long - term functional and morphologic deterioration of naive
rat kidneys and may contribute to changes of chronic allograft rejection . -
pubmed
A homozygous deletion in a
small cell lung cancer cell line involving a 3p21 region with a marked instability in
yeast artificial chromosomes . -
pubmed
A 61 - year - old
man developed progressive
weakness ,
numbness , and exercise - induced
vascular symptoms in the left hand . -
pubmed
To evaluate two different methods of managing segmental
skeletal defects , 15
patients treated with the open bone graft ( Papineau ) technique were compared with 17
patients who had intercalary bone transport ( Ilizarov ) management . -
pubmed
Both techniques shared several fixator - associated problems such as implant site
sepsis and
patient discomfort . -
pubmed
Experimental
colitis in
rats induces low - grade
endotoxinemia without
hepatobiliary abnormalities . -
pubmed
In three experimental models in
rats , surgical construction of a self - filling blind loop ( SFBL ) ,
trinitrobenzene sulfonic acid (
TNB ) -induced
colitis , and the combination of SFBL and TNB , the hypothesis was studied that intestine - derived endotoxins play a role in the pathogenesis of
hepatobiliary disorders in
chronic inflammatory bowel disease (
CIBD ) . -
pubmed
These results show that low - grade portal and systemic
endotoxinemia in
rats , induced by
bacterial overgrowth and/or chemical
colitis , is not able to induce hepatobiliary alterations . -
pubmed
To exclude definitively a possible role for
portal endotoxinemia in the pathogenesis of
CIBD - associated
hepatobiliary abnormalities , however , an adequate
animal model for
CIBD is urgently needed . -
pubmed
MATERIALS AND METHODS : A total of 108
patients with clinical
shoulder problems and 16
volunteers underwent MR imaging with a 1.5 - T unit . -
pubmed
The presence of AC joint fluid was associated with advancing
patient age , presence of
osteophytes , and fluid in the glenohumeral joint . -
pubmed
Gastroesophageal reflux and
cow 's
milk allergy in infants : a prospective study . -
pubmed
OBJECTIVE : The aim of our study was to determine the frequency of the association of
gastroesophageal reflux with
cow 's milk
protein allergy in patients win the first year of life . -
pubmed
The
cow 's milk - free diet and two successive blind challenges confirmed the diagnosis of
cow 's milk
allergy in 85 of the 204
patients with
gastroesophageal reflux . -
pubmed
In all ,
gastroesophageal reflux was associated with , and probably caused by
cow 's milk
allergy , in 85 of 204 cases ( 41.8 % ) . -
pubmed
CONCLUSIONS : Considering the frequency of this association , patients younger than 12 months old with symptoms of
gastroesophageal reflux should be carefully examined to determine whether this disorder is primary or caused by
cow 's milk
allergy . -
pubmed
In addition ,
re - infection following an episode of self - limited
infection or during chronic carrier condition has been described in
chimpanzees and in
man . -
pubmed
daily ) or placebo on erythrocyte membrane
cholesterol content and
acyl chain composition have been studied in 36
patients with a clinical history of
atherosclerosis enrolled in the Oxford
Cholesterol Study . -
pubmed
We report severe
nodulocystic acne in a 21 - year - old
man associated with
ectrodactyly of the right foot and
soft - tissue syndactyly of the third and fourth left fingers , and the first to fourth left toes . -
pubmed
Follow - up on 46 of 49
patients revealed
recurrence in 27 % ( actual survival 68 % ) ; however all three cases containing
tumour cells on immunohistochemistry were free from
recurrence . -
pubmed
Murine MPS I : insights into the pathogenesis of
Hurler syndrome . -
pubmed
Here we report on the long - term clinical , biochemical , and pathological course of
MPS I in
mice with emphasis on the skeletal and central nervous system ( CNS ) manifestations . -
pubmed
Skeletal manifestations represent the earliest clinical finding in
MPS I mice with histologic analysis of growth plate and cortical bone revealing evidence that significant early pathology is present . -
pubmed
This
murine model clearly shows phenotypic and pathologic features which mimic those seen in severe
human MPS I and should be an invaluable tool for the study of the pathogenesis of generalized storage disorders . -
pubmed
The severe
bleeding diathesis produced by intoxication with the venom of
Lonomia achelous caterpillars is characterized by prolonged
bleeding from superficial skin
wounds as well as massive
hemorrhage into body cavities . -
pubmed
[ Diagnostic catheterization and angiography in the examination of
patients with
ischemic heart disease ] . -
pubmed
We herein report the course of two pregnancies in a
hypoparathyroid woman treated with
calcitriol (
1,25 ( OH ) 2D3 ) . -
pubmed
A 29 - year - old
hypoparathyroid woman receiving chronic treatment with
calcitriol ( 0.25 microg / day ) and
calcium ( 1.5 g / day ) was referred in the 6th week of her first pregnancy . -
pubmed
To maintain
normocalcaemia the
calcitriol dose was increased to 0.5 microg / day during the 33rd week and to 0.75 microg / day shortly before delivery of a healthy
girl in the 3 7th week . -
pubmed
Obese subjects were divided into three groups according to the OGTT . -
pubmed
Furthermore , we discuss the significance of these ganglia in
prostatic cancer patients . -
pubmed
METHODS : The study group comprised a total of 42
patients , who had all undergone a radical prostatectomy for
prostate adenocarcinoma with a relatively small volume . -
pubmed
METHODS : Four hundred and thirty - two
patients with
unstable angina were enrolled . -
pubmed
Efficacy was assessed by the number of
patients experiencing any episode of recurrent
ischaemia as measured by computer - assisted continuous ECG
ischaemia monitoring . -
pubmed
Minor
bleeding and
thrombophlebitis occurred more frequently in the
efegatran treated
patients . -
pubmed
During infusions of autologous
rat RBCs , Q and total V increased threefold in response to
hypoxia , whereas normalized RBC TT ( TTRBC / TTPl ) and normalized tissue hematocrit ( HM / HS ) did not show a significant trend , indicating an increase in the number of pathways through which the RBCs can traverse the network because of spatial recruitment of capillaries . -
pubmed
In contrast , during infusions of
human RBCs , TTRBC / TTPl and HM / HS decreased significantly in response to
hypoxia . -
pubmed
Although Q exhibited an increase similar to that during
rat RBC infusions , VRBC exhibited a smaller increase compared with VPl , suggesting that reduced RBC deformability leads to a redistribution of RBCs through larger - diameter pathways within the network and exclusion of these RBCs from pathways normally recruited during
hypoxia . -
pubmed
Antinociceptive effect of
( S )- N - desmethyl trimebutine against a mechanical stimulus in a
rat model of
peripheral neuropathy . -
pubmed
Trimebutine (
2 - dimethylamino-2 - phenylbutyl 3,4,5 - trimethoxybenzoate ,
hydrogen maleate ) relieves
abdominal pain in
humans . -
pubmed
In the present study , the antinociceptive action of systemic
( S )- N - desmethyl trimebutine , a stereoisomer of
N - monodesmethyl trimebutine , the main metabolite of
trimebutine in
humans , was studied in a
rat model of
neuropathic pain produced by chronic
constriction injury to the sciatic nerve . -
pubmed
[ Study on biliary motility in
cirrhotic patients with
portal hypertension ] . -
pubmed
OBJECTIVE : To study biliary motility in cirrhotic
patients with
portal hypertension and analyze the relationship between these biliary motility and the degree of liver function . -
pubmed
METHODS : Biliary motility function was detected in 40
patients with
portal hypertension and 30 normal controls by using quantitative hepatobiliary scintigraphy . -
pubmed
CONCLUSION : Cirrhotic
patients with
portal hypertension often have abnormal motility of gallbladder and biliary duct . -
pubmed
Effect of rhythm regularization on left ventricular contractility in
patients with
atrial fibrillation . -
pubmed
In 10
patients with
atrial fibrillation , echocardiographic measures of left ventricular function - interval relations were used to assess contractility and to test the hypothesis that rhythm regularization produces a higher contractile state than is seen when the rhythm is irregular . -
pubmed
Lymphocytic hypophysitis in a
man presenting with
hypercalcemia . -
pubmed
A 59 - year - old
man with a 30 - year history of
type 2 diabetes mellitus presented with
fatigue ,
confusion , and
weight loss over a 3 - month period . -
pubmed
The
patient developed
pneumonia and
adult respiratory distress syndrome and died of an acute
myocardial infarction . -
pubmed
Pseudohypertension in a
patient with
diffuse scleroderma . -
pubmed
It has been described in
patients with
uremia ,
diabetes mellitus , and severe
atherosclerosis . -
pubmed
We report a case of
pseudohypertension in a 65 - year - old
man with diffuse
scleroderma . -
pubmed
This is the first reported case of
pseudohypertension in a
patient with
diffuse scleroderma . -
pubmed
Subcutaneous AIT for
allergic rhinoconjunctivitis and
allergic asthma has been successfully assessed in controlled studies with several clinically important allergens ( i. e.
birch- ,
grass- and
mugwortpollen ,
dust mites ,
animal dander ) and has shown convincing clinical efficacy . -
pubmed
Hymenopteravenom
hypersensitivity ( to
bee- and
wasp venom ) treated with AIT gives the best results compared to AIT with other allergens . -
pubmed
BACKGROUND : Diabetic
patients are at increased risk for both
macrovascular and microvascular disease compared with nondiabetic
patients . -
pubmed
METHODS : We conducted a prospective observational study to assess the control of multiple predetermined cardiovascular risk factors in 235 treated
diabetic patients undergoing elective cardiac catheterization at our institution between December 20 , 1997 , and February 15 , 2000 . -
pubmed
One hundred ninety - one ( 81 % )
patients had documented
coronary artery disease at cardiac catheterization . -
pubmed
The mean Hgb A1c level for all
diabetic patients was 8.2 % + /- 1.6 % . -
pubmed
PURPOSE : To report the prevalence and clinical significance of ocular findings in 20
patients with
Menkes ' syndrome recruited for a clinical trial at the National Institute of Child Health and
Human Development ( NICHHD ) . -
pubmed
PARTICIPANTS : Twenty
patients with
Menkes ' syndrome enrolled in a clinical trial at the NICHHD , who underwent ophthalmic evaluation at the National Eye Institute from 1990 through 1997 . -
pubmed
MAIN OUTCOME MEASURES : Prevalence of ophthalmic signs of unusual frequency in
patients with
Menkes ' syndrome . -
pubmed
RESULTS : There was a high prevalence of very poor visual acuity ( 8
patients ) ,
myopia at 21 months old or younger ( 5 of 9
patients this age who underwent cycloplegic refraction ) ,
strabismus ( 11 of 18
patients whose motility was evaluated ) , blue irides ( 15 of 16
patients whose iris color was documented ) ,
iris stromal hypoplasia and bilateral peripheral transillumination ( 7 and 3
patients , respectively ) , peripheral
retinal hypopigmentation ( 7 of 18
patients whose retinal periphery was noted at the initial examination ) , and
aberrant eyelashes ( 5
patients ) . -
pubmed
CONCLUSIONS :
Patients with
Menkes ' syndrome exhibit a high prevalence of several ocular findings , including some ( very poor visual acuity ,
myopia ,
strabismus ) that may warrant special care . -
pubmed
Early ocular examination is thus indicated for
patients with
Menkes ' syndrome , particularly those with mild variants of the disease , whose neurologic status is better and lifespan is longer . -
pubmed
We report the case of a 67 year old
patient admitted at our institution for acute onset of
left hemiplegia . -
pubmed
Fatty acid analysis of
Stenotrophomonas maltophilia clinical
strains showing different susceptibility to antibiotics at 30 and 37 degrees C. Isolates of
Stenotrophomonas maltophilia species display the feature " temperature - dependent susceptibility " ( TDS ) to antibiotics . -
pubmed
RESULTS :
Men with the AC / CC genotype exhibited
higher blood pressures than men with the AA genotype ; however , this relationship was not found among women . -
pubmed
We investigated this question with
individuals with
neurological damage who suffered from
deficits of attention . -
pubmed
We presented 4
patients with neurological complications caused by
B cell lymphomas as follows . -
pubmed
Our first
patient was a 67 - year - old
woman with primary
intracranial lymphoma whose onset simulated that of a
cerebral infarct . -
pubmed
The second
patient was a 52 - year - old
man with
lymphoma , who developed
myelopathy caused by an
intradural extramedullary spinal cord tumor . -
pubmed
The third was a 80 - year - old
man with
left cavernous sinus syndrome , which did not respond to therapies against
lymphoma . -
pubmed
The fourth was a 55 - year - old
man who presented with
numb chin syndrome on both sides , followed by multifocal lymphomatous involvement of the cranial nerves , spinal roots and leptomeninges . -
pubmed
Endosulfan ( 13mg / kg / day
body weight ) was administered orally to
mices via intragastric - during 10 days . -
pubmed
RESULTS : Statistical analysis showed significantly lower results for the
patient group in the Hospital for Special Surgery score , the Knee Society score , the patella score , and the Visual Analog Scale for
pain . -
pubmed
[ Protein utilization on the part of
human tumor cells cultivated in vitro ] . -
pubmed
On peripheral nerve electrical excitability in rachitic and
dystrophic children in the Tohoku district ] . -
pubmed
MATERIAL AND METHODS : Ten
subjects with
gingivitis , but no signs of destructive
periodontitis , were recruited . -
pubmed
The least - studied clinical association for
SOD is in
patients with
biliary pain and intact gallbladders . -
pubmed
Elevated basal sphincter of Oddi pressure is predictive of clinical response to sphincterotomy in
patients with
postcholecystectomy pain in two randomized sham - controlled studies . -
pubmed
However ,
patients with suspected
SOD have the highest complication rate from endoscopic retrograde cholangiogram and sphincterotomy , and , therefore , careful
patient selection is mandatory . -
pubmed
METHODS : Records were reviewed for all
patients seen during a 3 - year period who underwent EUS of the upper - GI tract for staging of known or suspected
malignancy . -
pubmed
Patients were included if there was histopathologic evidence of
malignancy , they had undergone noninvasive liver imaging within 6 weeks of EUS , and liver surveillance was specifically mentioned in the report of the EUS procedure . -
pubmed
Liver lesions were seen in 27
patients , 17 of whom had an abnormal noninvasive liver imaging test . -
pubmed
EUS - guided FNA of the liver was performed in 21
patients and was diagnostic of
malignancy in 15 ( 6.8 % ) , 5 of whom ( 2.3 % ) had normal noninvasive imaging . -
pubmed
EUS missed
liver lesions in 4
patients known to have abnormalities by other imaging modalities . -
pubmed
CONCLUSIONS : EUS can detect occult
liver metastases in
patients in whom noninvasive hepatic imaging studies are normal , although the frequency at which such lesions are detected is low . -
pubmed
[ Long - term curative effect of ventilation tube insertion for
otitis media with
effusion in adult
patients ] . -
pubmed
OBJECTIVE : To examine the long - term effect of ventilation tube insertion in treating
patients with non -
tumor adult - onset
otitis media with
effusion (
OME ) . -
pubmed
During 12 - 18 months following the operation , the ventilation tubes were extruded in 89
patients , among whom 55 had OME
recurrence . -
pubmed
The
recurrence of
OME following ventilation tube extrusion was significantly correlated to the pathological changes in the nose or nasopharynx of the
patients . -
pubmed
Fertility preservation should be an integral part of improving the quality of life in
cancer survivors ; however , it is neither possible nor ethical to recommend the same recipe for every
cancer patient . -
pubmed
Variation in initial state is described by initial
body weight ( BW0 ) , from which the chemical composition of the
pig is calculated . -
pubmed
If all
pigs in a group are
affected at the same stressor intensity ( e.g. -
pubmed
Consequently , decreasing the variation in initial
body weight and improving ability of
pigs to cope may be a better way of improving
pig performance than selecting only for increased growth potential . -
pubmed
[ Radiotherapy of
venereal tumors of the
dog ] . -
pubmed
Adjunctive use of atypical antipsychotics and anticholinergic drugs among
patients with
schizophrenia . -
pubmed
METHOD : We identified
patients with
schizophrenia from outpatient clinics in the Veterans Health Administration ( VA ) and defined initiation of
olanzapine or
risperidone as
patients who were not on any antipsychotics for 6 months and subsequently initiated on the target drug between 1/4/1999 and 31/3/2000 . -
pubmed
REVIEW SUMMARY : The frequency of
neurologic manifestations , more common in male Behcet
patients , is between 5 % and 30 % . -
pubmed
CONCLUSION :
Neuro - Behcet disease must be considered in the differential diagnosis of
stroke in young
adults ,
multiple sclerosis ,
movement disorders ,
intracranial hypertension ,
intracranial sinovenous occlusive diseases , and other
neurologic syndromes . -
pubmed
Increased late
sodium current in myocytes from a
canine heart failure model and from failing
human heart . -
pubmed
We studied I(
Na ) in
heart failure ventricular cells from a
canine pacing model of
heart failure and also from explanted failing
human hearts . -
pubmed
Peak I(
Na ) density was significantly decreased by 39 % and 57 % in the
dog model and in
human heart failure , respectively . -
pubmed
The
TMD sample comprised 90
patients ( 30
patients with
muscle disorders ; 30
patients with disc displacement with reduction ; 30
patients with
muscle disorders and disc displacement with reduction ) and was compared with 90 healthy control subjects . -
pubmed
A reproducible model of
cardiac hypertrophy in
rats . -
pubmed
CONCLUSION : We have developed a reproducible model of significant
left ventricular hypertrophy in
rats . -
pubmed
Protein chip array profiling analysis of sera from
neuroblastoma patients . -
pubmed
Neuroblastoma , the most common
extracranial solid tumour in
children , is characterised by highly heterogeneous clinical behaviour ;
patients are stratified into risk categories according to a combination of clinical and biological markers . -
pubmed
Aggressive surgical therapy and radiotherapy for
patients with high - risk
neuroblastoma treated with rapid sequence tandem transplant . -
pubmed
BACKGROUND / PURPOSE : The treatment approach for
patients with high - risk
neuroblastoma has been one of dose intensification chemotherapy and aggressive treatment of the primary
tumor . -
pubmed
Local
tumor control is examined in high - risk
patients treated with tandem stem cell transplant , aggressive surgery , and selected radiation therapy ( XRT ) . -
pubmed
Two
patients had local
recurrence after gross total resection . -
pubmed
One of the
boys also had severe global
developmental delay with abnormal findings from magnetic resonance imaging of the brain . -
pubmed
Genetic studies implicating the region of
human chromosome 18p11.2 in susceptibility to
bipolar disorder and
schizophrenia have observed parent - of - origin effects that may be explained by genomic imprinting . -
pubmed
METHODS : An
individual with
CFEOM1 ( classic autosomal dominant
CFEOM ) and
MG underwent a comprehensive ophthalmic examination . -
pubmed
OBJECTIVE : To identify predictive factors for work capacity in
patients with
musculoskeletal disorders . -
pubmed
The initial level of proliferative activity of different
tumour types of individual
patients --
carcinoma of oropharingeal zone , stomach , oesophagys , rectum ,
glioblastoma have been studied . -
pubmed
Acute kidney injury (
AKI ) occurs in about half of
patients in
septic shock and the mortality of
AKI with
sepsis is extremely high . -
pubmed
All
patients complained of symptoms and had a neurophysiological examination that might have indicated
CTS . -
pubmed
Effect of Shenfu injection on
ischemia -
reperfusion injury of
rat liver graft . -
pubmed
BACKGROUND : It is reported that Shenfu injection ( an injection prepared from traditional Chinese medicines
red ginseng and aconite root ) can decrease the extent of
ischemia - reperfusion injury to many organs , such as the heart and kidney . -
pubmed
We therefore investigated the effect of Shenfu injection on
ischemia -
reperfusion injury of
rat liver graft and its mechanism . -
pubmed
CONCLUSIONS : Shenfu injection has protective effect on
ischemia - reperfusion injury of
rat liver graft . -
pubmed
PURPOSE : To determine whether evidence - based standards exist regarding the indications for orbital exenteration in
patients with
orbital mucormycosis . -
pubmed
Reversible
posterior leukoencephalopathy syndrome after repeat intermediate - dose
cytarabine chemotherapy in a
patient with
acute myeloid leukemia . -
pubmed
A 56 - year - old
man was admitted to our hospital with
leukocytosis ,
anemia , and
thrombocytopenia . -
pubmed
On day 15 after the final infusion of
cytarabine , the
patient suffered
headache , and on day 21 , he experienced a decrease in sensation on the sole of his left foot . -
pubmed
Working memory related gamma oscillations in
schizophrenia patients . -
pubmed
Recent reports show that the capability of neural networks supporting high - frequency synchronization is reduced in the brain of
schizophrenia patients . -
pubmed
Specifically , deficits in gamma activity have been shown in
schizophrenia patients during perception and simple cognitive tasks . -
pubmed
The main objective of this study was to investigate modulation of event - related gamma responses in tasks varying working memory ( WM ) load in
schizophrenia patients ( N=10 ) and healthy controls ( N=10 ) . -
pubmed
During all three tasks
schizophrenia patients showed significantly slower reaction times and higher error rates than controls . -
pubmed
These results suggest that healthy subjects used various cognitive strategies depending on task difficulty , while
schizophrenia patients needed to initiate complex cognitive processes similar to those used during processing of novel contexts or stimuli even for the simple choice reaction task with low cognitive demand . -
pubmed
Prior reports on
patients with
myotonic muscular dystrophy ,
multiple sclerosis ,
Parkinson ' s disease , and
amyotrophic lateral sclerosis , have shown beneficial effects of
modafinil in treating
fatigue . -
pubmed
We report 4
patients with genetically confirmed
Charcot - Marie - Tooth disease who had significant
fatigue that was almost completely relieved by
modafinil . -
pubmed
Long - term treatment of
patients with recurrent unipolar
major depression : evidence to clinical practice . -
pubmed
Yersinia ruckeri causes the
enteric redmouth disease or
yersiniosis , an important
systemic fish infection . -
pubmed
Epizootic of
tularemia in an outdoor housed group of
cynomolgus monkeys (
Macaca fascicularis ) . -
pubmed
Tularemia is a highly contagious
infectious zoonosis , transmissible by inoculation , ingestion , or inhalation of the infectious agent
Francisella tularensis . -
pubmed
Pathologic findings were similar in all
monkeys that died and resembled the clinical picture of the
human disease , including an
ulceroglandular syndrome with
local lymphadenopathy ,
gingivostomatitis , and systemic spread , with manifestations such as subacute necrotizing
hepatitis ,
granulomatous splenitis , and
pneumonia . -
pubmed
This is the largest outbreak in
nonhuman primates and the first report of
tularemia in
cynomolgus monkeys . -
pubmed
An overview of the recent literature about
tularemia in
nonhuman primates is given . -
pubmed
We report a 65 - year - old female
patient who demonstrated
cardiac perforation ,
pulmonary cement embolism , and
tricuspid regurgitation , and these were all caused by
venous leakage of
polymethylmethacrylate as a complication of the procedure . -
pubmed
MATERIALS AND METHODS : Between April 1987 and December 1991 , 241 THAs with insertion of an ARRH were performed in 178 unselected , consecutive
patients ( average age 58 years ; range 30 - 84 years ) with a secondary
osteoarthrosis in 41 % of the cases . -
pubmed
Patients with pathologic diagnosis of invasive
breast carcinoma & lt;20 mm in size ( pT1 ) and undergoing BCT were selected . -
pubmed
RESULTS : Of 206
patients who underwent BCT for pT1
tumors , 84 ( 41 % ) needed re - excision . -
pubmed
CONCLUSIONS : These predictive factors could be useful in reducing the rate of re - excision as well as in identifying
patients with multifocal
tumors and/or extensive in situ
carcinoma whose
disease would be better managed by mastectomy . -
pubmed
Furthermore , chemically induced changes in gene regulation are associated with serious and complex
human diseases , including
cancer ,
diabetes and
obesity ,
infertility ,
respiratory diseases ,
allergies , and
neurodegenerative disorders such as Parkinson and
Alzheimer diseases . -
pubmed
METHODS : Three unrelated
patients with
congenital myopathy were investigated by muscle biopsy and genetic analysis . -
pubmed
RESULTS : All three
patients had early - onset
muscle weakness of variable severity and distribution . -
pubmed
The
patient died on postoperative Day 5 from
cardiac arrest . -
pubmed
Sixty - four Korean
schizophrenic patients were enrolled . -
pubmed
Chronobiology of
arterial hypertension in hemodialysis
patients : implications for home blood pressure monitoring . -
pubmed
METHOD : Data were collected from 71 participants ( 30 females , 41
males ) with
CP ( Gross Motor Function Classification System [ GMFCS ] levels I - V ) between the ages of 8 and 18 years . -
pubmed
Meningitis from an uncommon serotype of
Streptococcus pneumoniae in a young child . -
pubmed
Typhoid Meningitis : Cultivation of
Bacillus typhosus from Meninges and mesenteric Lymph Node in a Case of General
Paresis , with Note on Experimental
Typhoid Meningitis in the Guinea - Pig . -
pubmed
Phase I / II clinical trials of I d vaccination in
lymphoma demonstrated that some
lymphoma patients could mount immune responses that were correlated with a favorable clinical outcome . -
pubmed
Although I d vaccines induce immune responses in
myeloma patients , their efficacy is insufficient to provide a clear clinical benefit . -
pubmed
Severe
peritonitis due to
Streptococcus viridans following adjustable gastric banding . -
pubmed
Streptococci is a significant cause of
peritoneal dialysis peritonitis ( 6 % to 16 % of the cases ) , and
S. - pubmed
However ,
peritonitis due to
S. - pubmed
We herein report a non -
uremic case of a 38 - year - old male patient with severe
peritonitis due to
S. - pubmed
Epidemic encephalitis in military personnel ; isolation of
Japanese B virus on Okinawa in 1945 , serologic diagnosis , clinical manifestations , epidemiologic aspects and use of
mouse brain vaccine . -
pubmed
An actinomycete , designated
strain GIMN4.002(T ) , was isolated from a
tomato rhizosphere soil sample in Guangzhou , China . -
pubmed
Further , the morphological , physiological and biochemical characteristics of
strain GIMN4.002(T ) are distinct from
S. - pubmed
On the basis of the physiological and molecular properties observed , it is proposed that
strain GIMN4.002(T ) represents a novel species of the genus Streptomyces , for which the name
Streptomyces caeruleatus sp . - pubmed
We sought to investigate the impact of preoperative LV diastolic function on outcomes after SVR in
patients with
heart failure . -
pubmed
METHODS : Sixty - seven
patients ( 60 + /- 14 years ) with
LV systolic dysfunction ( LV ejection fraction , 0.27 + /- 0.10 ) underwent SVR . -
pubmed
CONCLUSIONS : In
patients with
LV systolic dysfunction undergoing SVR , preoperative restrictive LV diastolic filling pattern strongly related to higher mortality with aggravation of LV systolic function ,
mitral regurgitation grade , or LV remodeling . -
pubmed
Efficacy of guided imagery with theta music for advanced
cancer patients with
dyspnea : a pilot study . -
pubmed
BACKGROUND :
Dyspnea is a frequent and devastating symptom among advanced
cancer patients for which improved and low - cost palliative techniques are needed . -
pubmed
METHODS : A one - group repeated measures research design investigated the efficacy of guided imagery ( GI ) with theta music ( M ) on
dyspnea in advanced
cancer patients . -
pubmed
RESULTS : Participants included 53
patients , 33 % with
lung cancer . -
pubmed
DISCUSSION : This study demonstrates that GI / M is a useful intervention for palliative care of
patients with
dyspnea . -
pubmed
METHODS : Plasma metabolic products in
patients of
coronary heart disease (
CHD ) with
XBSS or non - XBSS and
subjects in the control group were identified by gas chromatographic mass spectrometry ( GC - MS ) type QP2010 , the changes of their main elements in different groups were analyzed by principal components analysis ( PCA ) and partial least squares ( PLS ) analysis . -
pubmed
Discrepancy analysis on 11 changeful metabolites showed that the contents of
arachidonic acid ,
octadecanoic acid ,
lactic acid ,
urea ,
beta - hydroxy butanoic acid and
oleic acid increased in
CHD patients , especially in those with
XBSS ( P & lt ; 0.01 ) . -
pubmed
In
CHD patients , contents of
lactic acid ,
beta - hydroxy butanoic acid ,
linoleic acid and
glucose in patients of XBSS pattern were higher than in non - XBSS pattern ( P & lt ; 0.01 ) ; content of
linoleic acid ,
glucose ,
alanine and
proline decreased in non - XBSS pattern while increased in XBSS pattern . -
pubmed
Content of
glucose in
CHD - XBSS
patients was significantly higher than that in the healthy control ( P & lt ; 0.01 ) . -
pubmed
Content of
citric acid was lower in
CHD patients , and showed significant difference between that in
CHD - XBSS
patients and healthy control ( P & lt ; 0.01 ) . -
pubmed
CONCLUSIONS : The major plasmic metabolites in
CHD -
XBSS patients are
arachidonic acid ,
octadecanoic acid ,
lactic acid ,
urea ,
citric acid ,
beta - hydroxybutyric acid ,
oleic acid ,
glucose , and
alanine . -
pubmed
Developmental changes of gene expression after
spinal cord injury in neonatal
opossums . -
pubmed
Changes in gene expression have been measured 24h after
injury to
mammalian spinal cords that can and can not regenerate . -
pubmed
By the use of
marsupial cDNA microarrays , we detected 158 genes that respond differentially to
injury at the two ages critical for regeneration . -
pubmed
Intensive chemotherapy for a
relapsed ALL patient who received living - donor lobar lung transplantation . -
pubmed
METHODS : Two investigators independently conducted a MEDLINE search from 1 January 2007 through 30 June 2010 for all publications reporting
EoE in
human subjects , and also searched the proceedings of the 2007 - 2010 American College of Gastroenterology and American Gastroenterological Association meetings , using a predefined search strategy . -
pubmed
Left ventricular inflow tract obstruction secondary to a
myxoma in a
dog . -
pubmed
This is the first description of a
left ventricular inflow tract obstruction secondary to a
myxoma in a
dog . -
pubmed
A 4 yr old , male
fox terrier presented with a 1 mo history of
cough and
exercise intolerance . -
pubmed
Eleven months after diagnosis , the
dog was euthanized at the owner 's request because of recurrent
congestive heart failure . -
pubmed
Vibratome - cut myocardial slices were prepared from left ventricular biopsies obtained from end - stage
heart failure patients undergoing heart transplant or ventricular assist device implantation , and from hearts of normal
dogs . -
pubmed
We conclude that viable myocardial slices with preserved structural , biochemical and electrophysiological properties can be prepared from adult
human and
canine heart biopsies and offer a novel preparation suitable for the study of
heart failure and drug screening . -
pubmed
OBJECTIVE : To investigate the levels of serum
cortisol in
patients with
uncomplicated Plasmodium falciparum ( P. falciparum ) malaria in an area of unstable
malaria transmission in eastern Sudan . -
pubmed
METHODS : The concentrations of
cortisol were measured in sera of 25
patients with
uncomplicated P. falciparum malaria ( at presentation , 24 h and 7 d later ) and 25 healthy
volunteers using radioimmunoassay gamma counter . -
pubmed
RESULTS : There was no significant difference in mean ( SD ) of total
cortisol levels in
patients with
malaria in comparison with the control group ; 602.2 ( 369.6 ) vs. 449.2(311.7 ) ng / mL , P=0.12 . -
pubmed
In
patients with
uncomplicated P. falciparum malaria , the mean ( SD ) presenting
cortisol levels were significantly higher in comparison to the levels on day 7 ; 602.2 ( 369.6 ) vs. 373.6(139.1 ) ng / mL , P=0.009 . -
pubmed
In the
patients with
uncomplicated P. falciparum malaria ( on presentation )
cortisol levels were not correlated with initial temperature or the presenting
parasitaemia . -
pubmed
Streptococcus parauberis isolates were divided into two serologically distinct types ( serotype 1 and serotype 2 ) , except for one
strain ( S1091 ) , using an agglutination assay with
rabbit antiserum , and serotype 1 was identified as the dominant type ( 24 of 29 isolates ) in this study . -
pubmed
In the pathogenicity test , the serotype 1
strains induced significantly higher mortality than the serotype 2
strains in
olive flounder when experimentally inoculated via the intraperitoneal route . -
pubmed
Attenuation of nonenzymatic glycation ,
hyperglycemia , and
hyperlipidemia in
streptozotocin - induced
diabetic rats by
chloroform leaf extract of
Azadirachta indica . -
pubmed
BACKGROUND : The hypoglycemic effects of
hexane ,
chloroform and
methanol extracts of leaves of
Azadirachta indica ( AI ) were evaluated by oral administration in
streptozotocin - induced severe
diabetic rats ( SD ) . -
pubmed
MATERIALS AND METHODS : The effect of chronic oral administration of the extract for 28 days was evaluated in
streptozotozin diabetic rats . -
pubmed
CONCLUSION :
Azadirachta indica can improve
hyperlipidemia and
hyperinsulinema in
streptozocin - induced
diabetic rats and , therefore , AI can be potentially considered to be an antidiabetic - safe agent . -
pubmed
METHODS : Sera were obtained from 40
periodontitis patients and 30 control
subjects . -
pubmed
RESULTS :
Periodontitis patients demonstrated significantly higher serum antibody titer to
P. - pubmed
RESULTS : Four
patients underwent the modified combined approach after
tumor resection and prior to postoperative radiotherapy in three of the four cases . -
pubmed
The
patient underwent surgical management with diagnosis of sigmoid
volvulus . -
pubmed
STUDY DESIGN : We analyzed data from 101
women randomized to undergo abortion with routine
pain control measures only (
ibuprofen and paracervical block ) or with the addition of intraoperative music via headphones . -
pubmed
PVX - potyvirus synergistic
infections differentially alter microRNA accumulation in
Nicotiana benthamiana . -
pubmed
In comparison to single
infections , co -
infection of
Nicotiana benthamiana with
Potato virus X (
PVX ) and
Potato virus Y (
PVY ) or
Plum pox virus (
PPV ) , resulted in increased
systemic symptoms ( synergism in pathology ) . -
pubmed
Our studies revealed that double
infection by
PVX and
PVY or
PPV that produced the most severe symptoms in
N. - pubmed
These findings indicate a differential effect on miRNA metabolism of the combined
infection by two unrelated plant viruses , which may account in part for the severe symptoms caused by
PVX / potyvirus - associated synergisms . -
pubmed
Subsequently , this concentration was tested in 2 herds with high and low
bovine tuberculosis prevalence , the latter with
paratuberculosis coinfection . -
pubmed
The protein cocktail did not induce reactions in
tuberculosis - free
cattle or in
paratuberculosis - infected
cattle . -
pubmed
We have also reported , for the first time in general practice , the presence of seasonal and
pandemic influenza viruses in the stools of adult patients consulting for uncomplicated
AD . -
pubmed
A simultaneous investigation of enteric and
influenza viruses in patients complaining of gastrointestinal symptoms could be useful for future studies to better identify the agents responsible for
AD . -
pubmed
The risk of developing
IAH is minimal in mechanically ventilated
patients with positive end - expiratory pressure & lt ; 10 cmH2O , PaO2 / FiO2 & gt ; 300 , and
BMI & lt ; 30 and without
pancreatitis ,
hepatic failure /
cirrhosis with
ascites ,
gastrointestinal bleeding or laparotomy and the use of vasopressors / inotropes on admission . -
pubmed
Transcatheter closure of a large
ASD from the femoral vein in a
patient with
Budd - Chiari syndrome . -
pubmed
Anomalies of the inferior vena cava are rare in
patients with isolated
atrial septal defect (
ASD ) . -
pubmed
Correlation of the gastroesophageal flap valve grade with the surgery rate in
patients with
gastroesophageal reflux disease . -
pubmed
METHODS : For 453
patients with symptoms suggestive of
GERD , GEFV grading and 24 - h ambulatory pH monitoring were performed . -
pubmed
We report successful closure of
ASD associated with
RAA using a 26 - mm atrial septal occluder in a 30 - year - old male
patient . -
pubmed
In this case report , we review the experience of a
patient who presented with early stage
pancreatic cancer ( Stage IIb ) who underwent a Whipple procedure and adjuvant chemoradiation . -
pubmed
As soon as the patient started
gemcitabine chemotherapy the
patient developed
gouty arthritis again , requiring discontinuation of chemotherapy . -
pubmed
The
patient received no additional treatment until his recent
recurrence 8 months later where
gemcitabine chemotherapy was again introduced with prophylactic medications consisting of
allopurinol 100 mg by mouth daily and
colchicine 0.6 mg by mouth daily throughout
gemcitabine chemotherapy , and no signs of
gouty arthritis occurred . -
pubmed
Further monitoring and management may be required in
patients receiving
gemcitabine chemotherapy with underlying
gout . -
pubmed
BACKGROUND : There are few data addressing local - regional
recurrence ( LRR ) and salvage therapies in
patients treated with neoadjuvant chemotherapy ( NCT ) compared to those treated with surgery first . -
pubmed
RESULTS : 56
patients had a LRR , for a crude
recurrence rate of 3 % . -
pubmed
For
patients with potentially curable
recurrence ( excluding distant
metastases within 3 months of LRR ) , the 5 - year OS , LC , and DMFS rates were 52 , 77 , and 69 % . -
pubmed
CONCLUSIONS : LRR is an uncommon event after BCT and many
patients with
LRR remain curable ( 5 - year OS & gt;50 % ) . -
pubmed
Our data indicate that NCT does not compromise salvage after LRR , providing further assurance that this strategy is safe for appropriately selected
breast cancer patients . -
pubmed
Compared to either single vaccine ,
HUVEC - HDM induced a more significant inhibition on the growth and
metastasis of
H22 hepatocellular carcinoma in
mice and prolonged the survival of
tumor - bearing
mice . -
pubmed
These results not only highlight the superiority of the combined HUVEC - HDM treatment regimen , but also support the translation of such approaches into the clinic for the treatment of
patients with
hepatocellular carcinoma . -
pubmed
The most common cause of
asthma exacerbations is
viral respiratory infections , particularly
human rhinovirus (
HRV ) . -
pubmed
METHODS : We used an in vitro coculture model of primary
human eosinophils and the
BEAS-2B epithelial cell line either stimulated with
HRV1A infection or
polyinosinic - polycytidylic acid (
poly [ I : C ] ) . -
pubmed
Efficacy of TACE in TIPS
patients : comparison of treatment response to chemoembolization for
hepatocellular carcinoma in
patients with and without a transjugular intrahepatic portosystemic shunt . -
pubmed
PURPOSE : To compare treatment response after transarterial chemoembolization ( TACE ) for
hepatocellular carcinoma (
HCC ) in
patients with and without a transjugular intrahepatic portosystemic shunt ( TIPS ) . -
pubmed
MATERIALS AND METHODS : A retrospective review of
patients who underwent conventional TACE for
HCC between January 2005 and December 2009 identified 10
patients with patent TIPS . -
pubmed
From the same time period , 23
patients without TIPS were selected to control for comparable Model for
End - Stage Liver Disease and Child - Pugh - Turcotte scores . -
pubmed
OBJECTIVE : To observe clinical and laboratory features of
valproic acid - induced
hyperammonaemic encephalopathy in
patients taking
valproic acid . -
pubmed
Ten
patients on
valproic acid therapy of any age group with
idiopathic or secondary epilepsy , who presented with
encephalopathic symptoms , were registered and followed up during the study . -
pubmed
RESULTS :
Hyperammonaemia was found in all
patients with
encephalopathic symptoms . -
pubmed
All
patients taking
valproic acid presenting with
encephalopathic symptoms must be monitored for the condition . -
pubmed
Synergistic effect of
cisplatin and synchrotron irradiation on
F98 gliomas growing in
nude mice . -
pubmed
This protocol showed a cure of 33 % of
rats bearing the
F98 glioma but the efficiency of the treatment was only measured in terms of overall survival . -
pubmed
Firstly , changes in
tumor growth of the
F98 glioma implanted in the hindlimb of
nude mice after the PAT - Plat treatment and its different modalities have been characterized . -
pubmed
OBJECTIVES : To assess the effectiveness of chest physiotherapy in relation to time until clinical resolution in
children ( from birth up to 18 years old ) of either gender with any type of
pneumonia . -
pubmed
Cervical
carcinogenesis is a consequence of persistent
infection with high - risk
human papillomaviruses (
HPVs ) . -
pubmed
Recent studies indicate that
HPV - transformed cells actively instruct their microenvironment to promote
carcinogenesis . -
pubmed
However , detailed analysis by two - dimensional immunoblotting and mass spectrometry showed that three
spots originating from betaA1 - crystallin were detected only in sera from
cataract patients . -
pubmed
Chromosome 10 , frequently lost in
human melanoma , encodes multiple
tumor - suppressive functions . -
pubmed
METHODS : The participants of this study were the
patients who have undergone chest CT for the examination of
pulmonary diseases in our institute . -
pubmed
METHODS : Clinical data of 115
patients with metachronous
liver metastasis in Tianjin Medical University Cancer Institute and Hospital between 1996 and 2008 were analyzed retrospectively . -
pubmed
RESULTS : Among 115
patients , the 1- , 3- and 5 - year non - hepatic
metastasis rates were 45.3 % , 14.8 % and 3.5 % respectively . -
pubmed
CONCLUSIONS : The size of
gastric cancer , vascular invasion ,
tumor differentiation and lymph node
metastasis are important factors associated with the risk of hepatic
metastasis from
gastric cancer in
patients after radical gastrectomy . -
pubmed
We report a case of intraosseous
mucoepidermoid carcinoma of the mandible in an 80 - year old female
patient developing from a previously diagnosed
dentigerous cyst . -
pubmed
Prospective monitoring of cytomegalovirus ,
Epstein - Barr virus ,
BK virus , and
JC virus infections on
belatacept therapy after a kidney transplant . -
pubmed
The aim of this single - center study was to compare the incidence of
viral infections ( cytomegalovirus ,
Epstein Barr virus ,
BK virus , and
JC virus ) , in 62 de novo kidney transplant
patients enrolled in the BENEFIT studies , receiving either belatacept ( n=42 ) or
cyclosporine ( n=20 ) . -
pubmed
Treatment of
patients with suspected
brain tuberculoma before or without bacteriologic confirmation in endemic places : report of two cases . -
pubmed
Reconstruction of
urethral strictures in
patients with a long history of blind
urethral dilatation . -
pubmed
Sixty
patients with a long history of blind
urethral dilatation ( group 1 ) were compared with 47
patients without prior dilatations ( group 2 ) . -
pubmed
The greatest improvement in symptoms and quality of life occurred three months after the surgery ( P & lt ; .05).Postoperative
infection was persistent in 20/107 ( 18.7 % )
patients . -
pubmed
RESULTS : A proposed management guideline for
patients with penetrating
abdominal trauma was created . -
pubmed
BACKGROUND & amp ; AIMS : Differences in intrahepatic gene expression patterns may be associated with therapy response in
peginterferon - treated
chronic hepatitis B (
CHB )
patients . -
pubmed
Genes upregulated in responders exhibited strongest similarity with a set of genes induced in livers of
chimpanzees with
acute Hepatitis B infection . -
pubmed
Acute
myocardial infarction patients were excluded . -
pubmed
Primary intra- and juxta - articular
vascular malformations of the temporomandibular joint : a clinical analysis of 8 consecutive
patients . -
pubmed
PATIENTS AND METHODS : This study retrospectively reviewed eight
patients ( seven
venous malformations and one
lymphatico - venous malformation ) who were treated for
intra - or juxta - articular vascular malformations of the temporomandibular joint from November 2005 to January 2011 . -
pubmed
All treated
patients had no clinical or radiographic signs of
recurrence . -
pubmed
We report here a
patient with generalized
poikilodermatous skin lesions whose diagnosis of
mycosis fungoides was made only a few years after the onset of his disease due to its bizarre clinical behavior and a natural reluctance to diagnose this disease in
children and adolescents . -
pubmed
Recent studies of beta - adrenergic antagonists suggest they may have neuroprotective effects that lead to improved functional outcomes in
rodent models of
ischemic stroke ; however , there are limited data in
patients . -
pubmed
We aimed to determine whether there was an improvement in mortality rates among
patients who were taking beta - blockers during the acute phase of their
ischemic stroke . -
pubmed
METHODS : A retrospective analysis of a prospectively collected database of
ischemic stroke patients was performed . -
pubmed
CONCLUSIONS : The continuation of home beta - adrenergic antagonist medication during the first 3 days of hospitalization after an
ischemic stroke is associated with a decrease in
patient mortality . -
pubmed
This supports the work done in
rodent models suggesting neuroprotective effects of beta - blockers after
ischemic stroke . -
pubmed
Previous clinical study has demonstrated that 30 - 40 % of
patients undergoing pancreaticoduodenectomy ( PD ) developed
hepatic steatosis . -
pubmed
Recently we encountered two
patients with
PD who later developed
NASH diagnosed by liver biopsy . -
pubmed
Case 1 was a 79 - year - old
woman who underwent PD for
intraductal papillary mucinous neoplasm (
IPMN ) . -
pubmed
Case 2 was a 71 - year - old
woman who underwent PD for
IPMN . -
pubmed
For each
patient , treatment of
infection and high - dose pancreatic enzyme supplements improved
liver dysfunction and
liver steatosis . -
pubmed
The aim of this study was to evaluate , in a large cohort of chronically transfused
patients , whether the presence of extramedullary hematopoiesis (
EMH ) accounts for the typical patterns of cardiac
iron distribution and/or cardiac function parameters . -
pubmed
We retrospectively selected 1,266
thalassemia major
patients who had undergone regular transfusions ( 611 men and 655
women ; mean age : 31.3 + - 8.9 years , range : 4.2 - 66.6 years ) and were consecutively enrolled within the Myocardial
Iron Overload in
Thalassemia network . -
pubmed
EMH was detected in 167 ( 13.2 % )
patients . -
pubmed
The role of outpatient ambulatory electroencephalography in the diagnosis and management of
adults with
epilepsy or
nonepileptic attack disorder : A systematic literature review . -
pubmed
Electroencephalography ( EEG ) is an established diagnostic tool with important implications for the clinical management of
patients with
epilepsy or
nonepileptic attack disorder . -
pubmed
In this paper , we present the results of a systematic review of the scientific literature on the use of AEEG in the diagnosis of
epilepsy and
nonepileptic attacks in adult
patients . -
pubmed
A 44 - year - old
man was referred to the hospital with rightsided
diminished hearing for 7 weeks , left - sided
facial palsy for 2 weeks , and left - sided
sensorineural hearing loss for 1 week . -
pubmed
Despite the recent advances in the development of antitumor therapies , the prognosis for
patients with
malignant gliomas remains dismal . -
pubmed
To determine whether AIs produce
hypersensitivity in
animal models of
pain , we examined the effects of the AI ,
letrozole , on mechanical , thermal , and chemical sensitivity in
rats . -
pubmed
Repeated injection of 5mg / kg
letrozole in
male rats produced mechanical , but not thermal ,
hypersensitivity that extinguished when drug dosing was stopped . -
pubmed
To determine whether sensitization of sensory neurons contributed to AI - induced
hypersensitivity , we evaluated the excitability of neurons isolated from dorsal root ganglia of male
rats chronically treated with
letrozole . -
pubmed
These results provide the first evidence that AIs modulate the excitability of sensory neurons , which may be a primary mechanism for the effect of these drugs to augment
pain behaviors in
rats . -
pubmed
The interpretation and discussion of these data and further extensive insights into drug discovery against
tuberculosis from natural products of plant biodiversity can be found in " Antimycobacterial and
cytotoxic activity of selected medicinal
plant extracts " [ 2 ] . -
pubmed
Onychomycosis due to
Candida parapsilosis in a Child with
Ventricular Septal Defect : An Unusual Predisposition . -
pubmed
Candida parapsilosis is emerging as a potential pathogen for
onychomycosis . -
pubmed
STUDY DESIGN : We studied 20
neonates who were admitted with a diagnosis of
HIE in the neonatal intensive care unit . -
pubmed
Cancer gene panel analysis of cultured circulating
tumor cells and primary
tumor tissue from
patients with
breast cancer . -
pubmed
Although numerous effective therapies have improved the survival rate of
patients with
breast cancer , a number of patients present with
tumor recurrence and
metastasis . -
pubmed
The analgesic mechanism of subcutaneous injections of diluted
bee venom into an acupoint is thought to be part of an anti - inflammatory effect and the central modulation of
pain processing . -
pubmed
Outcome Measures Changes in the
rats '
pain thresholds were assessed by evaluation of
pain - related behavior , using a tail flick latency unit . -
pubmed
Multimodality treatment including macroscopic complete resection ( MCR ) is currently the most effective therapy for
patients with
malignant pleural mesothelioma (
MPM ) . -
pubmed
Quantification of
Salmonella Survival and
Infection in an In vitro Model of the
Human Intestinal Tract as Proxy for Foodborne Pathogens . -
pubmed
Five
strains of
Salmonella Heidelberg and one
strain of
Salmonella Typhimurium were used to assess the robustness of the system . -
pubmed
Heidelberg strains originated from an outbreak , the fifth S. Heidelberg
strain and the
S . - pubmed
Recent discoveries have demonstrated the presence of
inflammation propagating substrates in the central nervous system of
patients afflicted with
ALS . -
pubmed
METHODS : A retrospective review of 80
patients ( 95 feet ) undergoing surgical treatment for
hallux rigidus was performed . -
pubmed
Smoking is inversely associated with possessing
HPV antibodies from a past
infection suggesting that smoking may influence acquiring subsequent
infections . -
pubmed
METHODS : In a cohort of 1976 U.S. women , we evaluate whether reduced antibodies to
HPV-16 is a mechanism for smoking 's role on acquiring a subsequent
HPV-16 infection , through the analytic technique of causal mediation analysis . -
pubmed
The results support current smoking as a risk factor earlier in the natural history of
HPV and are consistent with the hypothesis that smoking increases the risk of a subsequent
infection by reducing immunity . -
pubmed
A broad variety of
rodent motor tests are available to determine deficits after
stroke or
TBI . -
pubmed
The pathogenesis and etiology of
pancreatic cancer remain to be fully elucidated ; therefore , associated investigations are required to improve the outcome and prognosis of
patients . -
pubmed
The sole
isoprenoid quinone of
strain NS08 T was
menaquinone MK-6 and the DNA G+C content was 39.4 mol% . -
pubmed
The polar lipid compositions of
strain NS08 T and the type
strain of the type species of the genus Aquimarina ,
Aquimarina muelleri KCTC 12285 T , were very similar with
phosphatidylethanolamine , an unidentified
aminolipid and two unknown polar lipids as the major components . -
pubmed
New compound 1 was evaluated for its
cytotoxicities against five
human cancer cell lines :
HL-60 ,
SMMC-7721 ,
A-549 ,
MCF-7 and
SW480 . -
pubmed
Compound 1 showed significant inhibitory effects against various
human cancer cell lines with IC50 values ranging from 0.82 to 8.53 muM. -
pubmed
Global lipid profiling of pooled serum samples from 10
patients currently with
MDD (
cMDD ) , 10
patients with remitted
MDD (
rMDD ) , and 10 healthy controls revealed 37 differentially regulated lipids ( DRLs ) . -
pubmed
Previous studies suggest reduced cortical thickness in
patients with
obesity . -
pubmed
This study provides preliminary evidence of brain change following surgery , suggests increases in cerebral cortical thickness in
patients with greater excess
weight loss , and indicates the need for further investigation using larger samples and correlation with neurocognitive measures , such as memory recall . -
pubmed
No studies have assessed sensitivity to reinforcement contingencies that specifically select highly variable response patterns in
mice , let alone in models of
neurodevelopmental disorders involving limited response variation . -
pubmed
Operant variability and incremental repeated acquisition ( IRA ) were used to assess unique aspects of behavioral variability of two
mouse strains : BALB / c , a model of some deficits in
ASD , and C57Bl/6 . -
pubmed
Strain differences emerged , however , after novel learning sequences began alternating with the performance sequence : BALB / c
mice substantially outperformed C57Bl/6
mice . -
pubmed
These findings constrain the use of BALB / c
mice as a model of
ASD , but once again reveal this
strain is highly sensitive to reinforcement contingencies and they are fast and robust learners . -
pubmed
Autoantibody profile and clinical patterns in 619 Italian
patients with
cutaneous lupus erythematosus . -
pubmed
Improvements have been made in the outcomes of
patients with
NSCLC due to advancements in radiotherapy ( RT ) techniques , the use of concurrent chemotherapy with RT , and the emergence of immunotherapy as first- and second - line treatment in the metastatic setting . -
pubmed
RT remains the mainstay treatment in
patients with inoperable early - stage
NSCLC and is given concurrently or sequentially with chemotherapy in
patients with locally advanced unresectable disease . -
pubmed
Here , we describe the rationale for the integration of RT and immunotherapy in
patients with
NSCLC , present safety and efficacy data that support this combination strategy , review planned and ongoing studies , and highlight unanswered questions and future research needs . -
pubmed
First , advances in radiological imaging have suggested that a primary
breast tumor is absent in
OBC patients . -
pubmed
Next , the Delta1 viruses were used to determine the hierarchy of immunodominance by measuring the hemagglutination inhibition reactivity of
mouse antisera and plasma from 18
human subjects before and after seasonal
influenza vaccination in 2017 - 2018 . -
pubmed
This study revealed that antigenic site B is immunodominant in the
H3N2 influenza virus strain included in the current vaccine preparations . -
pubmed
Intragenomic polymorphism and intergenomic recombination in the ribosomal RNA genes of
strains belonging to a yeast species
Pichia membranifaciens . -
pubmed
In this study , we clearly showed that significant polymorphisms of the internal transcribed spacers ( ITS1 and ITS2 ) of ribosomal DNA ( rDNA ) exist within the genome of a
strain of the
yeast species
Pichia membranifaciens . -
pubmed
Using a C57BL6 / J
mouse model of diet - induced
obesity , we show that
mannose supplementation of high - fat - diet - fed
mice prevents
weight gain , lowers adiposity , reduces
liver steatosis , increases endurance and maximal
O2 consumption , and improves
glucose tolerance . -
pubmed
Selenium amelioration of
arsenic toxicity in
rice shows genotypic variation : A transcriptomic and biochemical analysis . -
pubmed
Significant decrease in
As accumulation ,
H2O2 content , and fluorescent intensity of
nitric oxide (
NO ) , reactive
oxygen species ( ROS ) , and
superoxide radical ( O2.- ) along with cell
death with
Se supplementation in both
rice varieties demonstrated the protective role of
Se as a probable ROS quencher . -
pubmed
CONCLUSIONS : This exploratory study found trialling an adapted approach to the Alert Program that uses sensorimotor - based approach decreased
tic severity in
children with
tic disorders . -
pubmed
Implementation of
tranexamic acid for
bleeding trauma patients : a longitudinal and cross - sectional study . -
pubmed
RESULTS : Among 228 250 patients , the proportion of
trauma patients treated with
TXA increased from near zero in 2010 to 10 % ( 4593 ) in 2016 . -
pubmed
CONCLUSIONS : There is a low proportion of
patients treated with
TXA across the range of
injury severity and the range of physiological indicators of severity of
bleeding . -
pubmed
Most
patients receive treatment within the existing target of 3 hours from
injury , however there remains the potential to further improve major
trauma outcomes by the earlier treatment of a wider
patient group . -
pubmed
This article describes the clinical presentation , our treatment approach , and short - term outcomes for three pediatric
patients with multiligamentous
injuries of the knee and reviews the current literature relating to these uncommon
injuries . -
pubmed
CONCLUSION : This multi - electrode ablation catheter could cause minor
injury to renal artery instantly after RDN , but it is found to be safe in the
animal model at 1 - month follow - up . -
pubmed
Brain metabolism modulates neuronal excitability in a
mouse model of
pyruvate dehydrogenase deficiency . -
pubmed
However , the principles that govern their relationship are not always intuitive because heritable
defects of brain glucose metabolism are associated with the paradoxical coexistence , in the same
individual , of episodic neuronal hyperexcitation (
seizures ) with reduced basal cerebral electrical activity . -
pubmed
Does lumbar mobilization help
stroke patients to improve functional outcomes ? -
pubmed
The current study aimed to observe effects of lumbar mobilization on gait of
stroke patients . -
pubmed
Quasiinterventional study was conducted on 30
stroke survivors . -
pubmed
Sample included either gender with onset of
stroke ( & gt;03 - months ) ,
patients with other pathologies were excluded . -
pubmed
The Current study suggested lumbarmobilization to be effective in improving gait in
stroke survivors . -
pubmed
Lengthening temporalis myoplasty and reduction of the swallowing oral phase dysfunction in
facial palsy patients . -
pubmed
The aim of this study was to determine whether lengthening temporalis myoplasty could reduce the dysfunction in the oral phase of swallowing in
patients with
facial palsy . -
pubmed
METHODS : 158
patients with
BC treated in Yantai Yuhuangding Hospital from September 2015 to December 2017 were retrospectively analyzed . -
pubmed
Methods Between January 2003 and June 2008 , 150
patients were treated with radiosurgery for classical or symptomatic
TN . -
pubmed
Conclusion Immediate
pain relief leads to sustained relief and
patients present significantly better
pain outcomes in comparison to those without immediate relief . -
pubmed
Objective : To report our single - center experience in terms of
patient clinical characteristics , treatment outcomes , and chemotherapy - related toxicities in
patients with low - risk
gestational trophoblastic neoplasia (
GTN ) . -
pubmed
No
patient developed
MTX - related
hepatic toxicity or
ActD - related
blister formation . -
pubmed
The primary endpoint was
patient - reported shoulder - related
pain . -
pubmed
Although
tumor immune checkpoint inhibitors therapy brings survival benefits to
cancer patients , it also faces many challenges , such as the occurrence of immune - mediated
hepatotoxicity . -
pubmed
The Delayed Neuroprotective Effect of
Methylene Blue in Experimental
Rat Brain Trauma . -
pubmed
However , on the 180th day after
TBI , the magnetic resonance imaging scan of the
animal brains did not show a significant reduction in the volume of the lesion in
MB - treated
animals . -
pubmed
Recently , a pathogen has been identified as a novel coronavirus (
SARS - CoV-2 ) and found to trigger novel
pneumonia ( COVID-19 ) in
human beings and some other mammals . -
pubmed
Methods : A retrospective interventional study that analyzes cases of
congenital cataracts operated on a group of 14
children with
Down syndrome , respectively on 26 eyes , was performed . -
pubmed
The age of the
children at the time of the surgery , the presence of associated
ocular and systemic anomalies , the employed surgical technique , the frequency and the type of
postoperative complications , were examined . -
pubmed
Herein , we aim to summarize the relative efficacy and safety of all available diuretics used in the treatment of
patients with
HF . -
pubmed
Diuretics are the main treatment of
hypervolemia in
HF patients . -
pubmed
Spontaneously
hypertensive rats ( SHRs ) and WKY
rats were treated with VA deficiency ( VAD ) or normal ( VAN ) fodder for 20 weeks . -
pubmed
Therapeutic Drug Level Monitoring of
Teicoplanin in Korean Pediatric
Patients with Normal versus
Impaired Renal Function . -
pubmed
Therefore , the aim of this study was to investigate the therapeutic drug level monitoring of
teicoplanin in Korean pediatric
patients , including those with
impaired renal function . -
pubmed
Distribution and characteristics of trough levels in
patients with
decreased renal function and those with
bacteremia were also assessed . -
pubmed
Median trough levels were higher in
patients with
decreased renal functions ( P < 0.001 ) . -
pubmed
CONCLUSION : This study provides additive information on trough level monitoring of
teicoplanin in
children with
impaired renal function and treatment effect in
patients with gram - positive
bacteremia . -
pubmed
METHODS :
HCC was induced in
rats using a single dose of
diethyl nitrosamine (
DENA ) ( 200 mg / kg , ip ) , followed by
phenobarbital sodium ( 0.05 % ) in drinking water for 18 weeks . -
pubmed
The history of ever having performed fellatio was associated with
pharyngeal infection with
N. - pubmed
There was , however , no association between
pharyngeal infection with
N. - pubmed
The authors evaluated 48 curves for the right and left kidney of 24
children free from any
disorder of the uropoietic system , in whom radiorenography formed part of a general examination . -
pubmed
The percentual differences in the curves were compared with the findings in a group of 64
children with
cystopyelonephritis . -
pubmed
Immunoselective loss of parental h antigens by somatic reduction in an H-2 a / H-2 b hybrid
mouse leukemia . -
pubmed
Spirolactones (
spironolactone ,
potassium canrenoate ) may produce secundary sexual effects such as
gynecomastia in
man and
menstrual disturbances in
women . -
pubmed
Immune electron microscopy was performed on a serum pair and faeces from one of the
patients with
astrovirus . -
pubmed
[ Correlation between immuno - morphological parameters of regional lymph nodes and the mortality of
patients with
stage I and II bronchial squamos cell carcinoma ] . -
pubmed
, at least 16h before the earliest signs of
thalidomide dysmelia have been reported in
rabbits ( Vickers , ' 67 ) . -
pubmed
Since the dorsal root ganglia form in
rabbits on days 11 and 12 the changes evident at day 13 indicate that degeneration of neurons and axons may be a pathogenetic factor in
thalidomide - induced
peripheral deformities . -
pubmed
In a 44 - year - old
woman , a
pancreatic pseudocyst was demonstrated on delayed images obtained up to 8 days after the intravenous administration of 0.250 mCi
75Se - selenomethionine . -
pubmed
Prostaglandin release in
canine acute
haemorrhagic pancreatitis . -
pubmed
Chromatographic analysis of the peritoneal exudate from the
dogs with
pancreatitis showed high levels of
prostaglandin E - like material ( mean 43 ng / ml
prostaglandin E2 equivalents ) . -
pubmed
We examined twenty pregnant
women with suspected
rupture of membranes and twenty women with apparently intact membranes receiving routine prenatal care . -
pubmed
A case report involving
buspirone hydrochloride in the successful treatment of a
patient with an atypical
paraphilia and
transvestic fetishism is presented . -
pubmed
It is recommended in addition to echocardiography when
cardiac tumors are suspected , especially in
patients with
tuberous sclerosis . -
pubmed
Lactational [ correction of Lacational ]
anovulation in
rats and its dependency on
progesterone . -
pubmed
The same was true of 5 %
permethrin cream ( 2.5 % in
children below 5 years of age ) used in the treatment of
scabies . -
pubmed
Benzyl benzoate has an irritant potential , and
lindane has been reported to exert
CNS toxicity in a few anecdotal cases , in particular in small children or after repeated applications in
patients with
scabies crustosa , and
permethrin was distinctly superior to both of these . -
pubmed
This is documented by the results obtained in the treatment of 48
children and 56
adults suffering from
scabies . -
pubmed
Permethrin is recommended in
scabies therapy in premature infants , small
children ,
patients with
seizures and
neurological complications , in treatment failures with
lindane entailing the need to repeat the therapy , in
scabies crustosa and in pregnant women and nursing mothers . -
pubmed
The techniques of Southern , Northern , and Western blotting along with in situ hybridization and immunohistochemistry are all applicable to the analysis of oncogene status in
human solid tumors . -
pubmed
Qualitative and quantitative alterations of these genes may be associated with the transformation and progression of
human solid tumors . -
pubmed
The existing follow - up standard for
breast cancer patients has been reviewed by a representative trial involving 1,004 curatively treated
patients , who underwent surgery between 1977 and 1987 . -
pubmed
One hundred consecutive
patients were prospectively studied to assess the clinical and biochemical features of symptomatic
choledocholithiasis . -
pubmed
Pain was the most frequent symptom of
choledocholithiasis , observed in 75 % of the
patients , but rarely occurred alone ( 12 % ) . -
pubmed
These results indicate that , in
patients with suggestive symptoms ,
choledocholithiasis is unlikely in the absence of biochemical abnormalities in the first three days following the onset of symptoms . -
pubmed
Altered subsets of peripheral blood lymphocytes in
patients with
HTLV - I associated myelopathy (
HAM ) . -
pubmed
We studied subsets of peripheral blood lymphocytes ( PBL ) from 12
patients with
human T - lymphotropic virus type I ( HTLV - I ) associated myelopathy (
HAM ) . -
pubmed
The effect of therapeutic irradiation upon B lymphocyte function was investigated in
patients with various
malignancies . -
pubmed
Acetaminophen toxicosis : a potential model for
acute liver failure in
swine . -
pubmed
Male crabs (
Chasmagnathus granulatus ) exhibited a defensive response ( DR ) to an electric
shock ( 8 V , 50 Hz , 1 sec ) . -
pubmed
High - dose continuous infusion
folinic acid and bolus
5 - fluorouracil in
patients with advanced
colorectal cancer : a phase II study . -
pubmed
Encouraging results have recently been reported for studies using
folinic acid in combination with
5 - fluorouracil (
5 - FU ) in the treatment of
patients with
gastrointestinal ( GI ) malignancies . -
pubmed
Thirty - six
patients with advanced
colorectal cancer with unequivocal evidence of progression while treated with
fluoropyrimidines were treated with a six - day continuous infusion of 500 mg / m2 / d of
folinic acid initiated 24 hours before a five - day course of 5 - FU administered as an intravenous ( IV ) bolus of 370 mg / m2 / d. An initial dose of 250 mg / m2 / d of 5 - FU was used in
patients previously treated with ionizing radiation and/or a
nitrosourea . -
pubmed
Tumor cells were found in the blood only at end - stage disease in a minority of
animals . -
pubmed
To elucidate possible mechanisms by which
coenzyme Q10 enhances reoxygenation - induced recovery of cardiac contractile force after
hypoxia ,
rabbit hearts were subjected to hypoxic perfusion for 20 min , followed by 45 min - reoxygenation with or without pretreatment with
coenzyme Q10 . -
pubmed
We performed cellular analysis of bronchoalveolar lavage fluids ( BALF ) from 20
patients in different stages of
idiopathic pulmonary fibrosis (
IPF ) and compared the results with those from 16 controls and 10
sarcoidosis patients . -
pubmed
Patients with
IPF were divided into infiltrative and fibrotic groups as diagnosed by transbronchial lung biopsy and chest x - rays . -
pubmed
Promotional effects of
testosterone and high fat diet on the development of
autochthonous prostate cancer in
rats . -
pubmed
Depots of
testosterone implanted in Lobund -
Wistar ( L - W ) rats , resulted in increased incidence of
prostate adenocarcinomas (
PAs ) in the dorsal lateral lobe area . -
pubmed
In
testosterone - treated
rats which had been fed the same diet plus 15 %
corn oil , the
prostate tumors were more numerous and they appeared earlier . -
pubmed
Rats consuming the same feed containing 15 %
corn oil ( no
testosterone ) did not produce
prostate tumors . -
pubmed
Sixty - seven
patients with
idiopathic membranous glomerulonephritis (
iMGN ) were analyzed clinically . -
pubmed
During the follow - up ( mean 6.7 years )
renal death occurred in four
patients 12 - 151 ( mean 84.2 ) months after the diagnosis of
iMGN . -
pubmed
Patients with slight
proteinuria never showed
loss of renal function . -
pubmed
The retrospective comparison of survival in
patients who did ( N = 31 ) or did not ( N = 19 ) receive
corticosteroids and/or immunosuppressive drugs for the treatment of
NS revealed no evident difference at 5 or 10 years . -
pubmed
This clinical analysis emphasizes the fairly favorable outcome of
patients with
iMGN . -
pubmed
Mycoplasma meleagridis infection : development of lesions and distribution of
infection in
turkey embryos . -
pubmed
[ Experimental contributions to the knowledge of the
dermatitis pustulosa in
sheep . -
pubmed
Tumors and other lesions induced by
murine sarcoma viruses . -
pubmed
A new vaccine
strain of
feline panleukopenia virus grown in
ferret cell culture . -
pubmed
A comparative study of
mouse foot pad inoculation of skin biopsy specimens from patients with
lepromatous leprosy in San Francisco and Atlanta . -
pubmed
We are reporting the case of a
patient with this anomaly without concomitant
arteriosclerotic involvement who was managed surgically . -
pubmed
A 46 - year - old
woman was seen with disabling
angina of 8 months ' duration . -
pubmed
Localization of the defect in
skin diseases analyzed in the
human skin graft - nude
mouse model . -
pubmed
In order to validate the use of the nude
mouse human skin graft system in the analysis of
skin defects , we have demonstrated that a systemic metabolic defect which involves the skin , namely essential
fatty acid deficiency , can be differentiated from a defect residing primarily in the skin itself . -
pubmed
In previous studies ,
lamellar ichthyosis was shown to be well maintained after prolonged periods of growth on
nude athymic mice , indicating that the defect in this disease resides in the skin itself . -
pubmed
Psoriasis is well maintained on the nude
mouse - skin graft model . -
pubmed
The
epidermal hyperplasia and hyperproliferative epidermal cell kinetics of
psoriasis are manifested in the grafts of active
psoriasis maintained for prolonged periods on the
nude mice , but the inflammatory component of
psoriasis is absent . -
pubmed
The medial
fracture of the femur neck is mainly a
fracture of the old
man . -
pubmed
For this analysis the concentration
magnesium ,
copper and
zinc was performed from 10
patients which got a medial
fracture of the femur neck . -
pubmed
There are no significant alterations in blood levels of
magnesium ,
copper and
zinc in
patients with a medial
fracture to normal population . -
pubmed
We investigated the connection between the
pulmonary hypertension and the lung function in the preoperative time of 176
patients undergoing an operation for prosthetic valve replacement in mitral and aortal position and in both of them . -
pubmed
A
patient was seen with secondary
cluster headache whose acute
pain responded promptly to
sumatriptan . -
pubmed
Backscattered electron imaging and energy - dispersive X - ray microanalysis studies of evidence for
calcium salt heterogeneity in fifteen
gallstones from an elderly
human . -
pubmed
PATIENTS :
Patients ( N = 426 ; ages , & gt ; or = 65 years ) who were undergoing
cataract surgery . -
pubmed
CONCLUSIONS : Preoperative data can identify
patients who are likely to have improvements in visual function after
cataract surgery . -
pubmed
[ Intraperitoneal perfusion of compound injection of
salvia miltiorrhiza with dachengqi decoction in treating adhesive
intestinal obstruction ] . -
pubmed
The purpose of this study was to evaluate risk factors associated with
peripheral vascular disease (
PVD ) in
patients with
non - insulin - dependent diabetes mellitus (
NIDDM ) . -
pubmed
A group of 100
patients ( 50
men and 50
women ) aged 50 years or over with
PVD and another group of 200 age - sex - matched
patients ( 100
men and 100
women ) without
PVD were studied . -
pubmed
[ Effect of a new anticancer drug ,
docetaxel (
RP56976 ) , on
human leukemia cell lines ] . -
pubmed
The antitumor effect of a new derivative of
taxol ,
docetaxel (
RP56976 ) , was examined in
K562 human tumor system in vitro . -
pubmed
The authors report results of an 8 - week , open trial of
desipramine in 42
patients with
DSM - III - R dysthymia with a concurrent diagnosis of
major depression ( " double "
depression ) and 33 patients with
dysthymia who had no other
depressive diagnosis ( " pure "
dysthymia ) . -
pubmed
Either complete or partial remission was achieved by 70 % of the
patients with " pure "
dysthymia . -
pubmed
In
patients with the clinical diagnosis of
Alzheimer disease (
AD ) , we searched for systemic changes in components of the blood as a diagnostic tool . -
pubmed
Combination chemotherapy for
infections due to
methicillin - resistant
Staphylococcus aureus with combination therapy by
cefuzonam and
fosfomycin or
minocycline in the urologic field . -
pubmed
In this paper recent several reports were introduced and discussed on new opinion of
precancerous conditions such as
adenoma ,
intestinal metaplasia ,
gastric ulcer , remnant stomach and
H. - pubmed
Gastric
carcinogenesis for
ulcer , remnant stomach and
H. - pubmed
A sixty - year old
woman had
muscle pain of her extremities and
stiffness in her fingers after unusual physical exertion . -
pubmed
The rejection - free interval ( RFI ) following RATG treatment in group A was 21.6 + /- 10 days and 22 + /- 11 in group M. In group M , 3 of 27
patients ( 11 % ) had a rejection treatment - related
infection ( 2 bacterial ; 1 viral ) versus 6 of the 42
patients of group A ( 14.2 % ; bacterial 1 , viral 5 ) . -
pubmed
Children actuarial survival at 1 , 12 and 48 months was respectively 66 % , 60 % and 60 % versus 92 % , 86 % and 85 % ,
deaths occurring earlier in the urgent group . -
pubmed
BACKGROUND : We investigated the incidence of axillary lymph node
metastases in
patients with T1a ( & lt ; or = 0.5 cm ) and T1b ( & gt ; 0.5 cm and & lt ; or = 1.0 cm )
breast cancers . -
pubmed
METHODS : The charts of 2000
patients who underwent axillary lymph node dissection for
breast cancer at our institution from 1989 to 1991 were reviewed . -
pubmed
Of these , 81
patients had T1a and 166 had T1b primary
breast cancers . -
pubmed
Of those , 6 of 60 ( 10.0 % )
patients with T1a and 23 of 152 ( 15.1 % ) with T1b
tumors had positive nodes . -
pubmed
BACKGROUND : The authors previously showed that
children require larger infusion rates of
mivacurium than
adults to maintain target twitch
depression . -
pubmed
Superfusion of
( 1S,3R )- ACPD produced a concentration - dependent ventral root depolarization in naive and
hyperalgesic animals with no significant difference in EC50 values ( 55.5 + /- 6.36 microM and 51.0 + /- 5.76 microM , respectively , n = 4 ) . -
pubmed
However , the amplitude of the maximum response was significantly enhanced by 23 % in
hyperalgesic compared with naive
animals . -
pubmed
Altered activities of these substances in
patients with risk factors for
cardiovascular disease ( e.g. -
pubmed
This review describes the role of
NO in
human health and disease and summarizes strategies currently being used to measure and improve
endothelial dysfunction . -
pubmed
Anesthetized , physiologically monitored male
Wistar rats received 12.5 min of global
forebrain ischemia by bilateral common carotid artery occlusions plus
hemorrhagic hypotension to 45 mmHg . -
pubmed
Hyperglycemic animals received
dextrose ( 2.5 ml of a 25 % solution , intraperitoneally ) prior to
ischemia ; this doubled the mean plasma
glucose concentration to 296 mg/100 ml . -
pubmed
The neocortex and striatum of NI
rats showed only mild damage , while the majority of
HI rats had extensive lesions , and several showed large cortical , striatal or thalamic
infarcts . -
pubmed
In addition , widespread cortical ischemic neuronal changes were evident in
HI animals . -
pubmed
By contrast ,
HI rats showed prominent peri- and intravascular polymorphonuclear and monocytic accumulation evident at 24 h ; frequent white cell
thrombi in pial arterioles on day 3 ; and thickening of vascular endothelium , with foci of parenchymal rarefaction or
microinfarction adjacent to occluded vessels . -
pubmed
Prominent microglial activation , often along the course of penetrating blood vessels , was common in the striatum and neocortex of
HI animals but was much less extensive in the NI group . -
pubmed
Activated microglia in
HI rats were typically
hypertrophic and amoeboid . -
pubmed
In the group of
rats ( n = 10 ) operated on by using a straight IVC graft , graft
congestion was seen and only 1
rat could survive over 1 day . -
pubmed
Cutting edge : functional characterization of the effect of the
C3H / HeJ defect in
mice that lack an Lpsn gene : in vivo evidence for a dominant negative mutation . -
pubmed
The impact of nutritional status on the prognoses of
patients with advanced
head and neck cancer . -
pubmed
BACKGROUND :
Malnutrition has been recognized as a poor prognostic indicator for
cancer treatment - related morbidity and mortality in general , and it is reported to affect 30 - 50 % of all
patients with
head and neck cancer . -
pubmed
In this study , the correlation of nutritional status with 3 - year survival was studied prospectively in 64
patients with T2 - T4
carcinomas of the head and neck who were treated surgically with curative intent ; the surgery was often followed by radiotherapy . -
pubmed
CONCLUSIONS : Apart from the well - known prognostic parameters lymph node status ( T classification ) and status of
surgical margins , preoperative
weight loss and occurrence of major
postoperative complications were also found to have a negative effect on the survival of male
patients undergoing surgery for advanced
head and neck cancer . -
pubmed
ARCTIC : assessment of haemodynamic response in
patients with
congestive heart failure to
telmisartan : a multicentre dose - ranging study in Canada . -
pubmed
The beneficial effects of
peroxynitrite on
ischaemia - reperfusion
arrhythmias in
rat isolated hearts . -
pubmed
These results suggest that
ONOO (- ) at a low concentration may exert beneficial effects on
ischaemia - reperfusion - induced
arrhythmias in
rat isolated hearts . -
pubmed
About 25%-30 % of
patients with
non - small cell lung cancer can be resected with curative intent . -
pubmed
However , systemic
relapses occur in up to 70 % of these
patients . -
pubmed
[ Cotreatment of
amyotrophic lateral sclerosis patients ] . -
pubmed
Riluzole is a only drug which prolongs survival in
amyotrophic lateral sclerosis (
ALS )
patients , however its effect is modest . -
pubmed
We review the preclinical data supporting combination treatment for
ALS and discuss the possible combination treatment in
patients with
ALS . -
pubmed
Between 1982 and 1994 13
patients have needed surgery for
priapism persisting after conservative measures using the technique described by Quackel . -
pubmed
MATERIAL AND METHODS : 63
patients with
osteogenesis imperfecta underwent a total of 186 primary intramedullary fixations with Bailey - Dubow rods during period 1984 - 1996 . -
pubmed
Patients either suffered from knee - joint migration of the distal nail ( 3.9 % ) , proximal nail migration ( 7.9 % ) , detached T - pieces from the sleeve ( 7.9 % ) or
chronical nail infection ( 1.0 % ) . -
pubmed
Patients with diffuse large - cell type had better survival than
patients with small noncleaved - cell type in
Stage II high - grade lymphoma . -
pubmed
Effect of
ozone and
nitrogen dioxide on the release of proinflammatory mediators from bronchial epithelial cells of nonatopic nonasthmatic subjects and
atopic asthmatic patients in vitro . -
pubmed
OBJECTIVE : to analyze the clinical features and associated morbidity in a group of
patients with
vascular dementia (
VD ) . -
pubmed
METHODS : we retrospectively evaluated 25
patients with diagnosis of
VD , based on the State of California
Alzheimers Disease Diagnostic and Treatment Centers ( ADDTC ) criteria . -
pubmed
IMPLICATIONS : This is a case report of a
disk infection (
discitis ) caused by the bacteria ,
Streptococcus bovis after spinal anesthesia for cesarean delivery . -
pubmed
Allergy to soy formula and to extensively hydrolyzed whey formula in infants with
cow 's
milk allergy : a prospective , randomized study with a follow - up to the age of 2 years . -
pubmed
OBJECTIVES : We conducted a prospective , randomized study to evaluate the cumulative incidence of
allergy or other adverse reactions to soy formula and to extensively hydrolyzed formula up to the age of 2 years in infants with confirmed
cow 's
milk allergy . -
pubmed
STUDY DESIGN :
Infants ( n = 170 ) with documented
cow 's
milk allergy were randomly assigned to receive either a soy formula or an extensively hydrolyzed formula . -
pubmed
Soy formula can be recommended as a first - choice alternative for infants & gt;or=6 months of age with
cow 's milk
allergy . -
pubmed
Uterine
flushings were obtained under transvaginal ultrasonographic control from 132
women presenting for investigation and treatment of
infertility . -
pubmed
The overall frequency of these complications ( which involved the genito - urinary tract in over 75 % of cases ) regarded 5.3 % of all admission for
HIV disease , with a clear prevalence of
Enterococcus faecalis as the causative agent ( 86.5 % of episodes ) , and a proportionally elevated frequency of
polymicrobial infection ( 45.9 % of cases ) . -
pubmed
An advanced underlying
HIV disease characterized by a concurrent , severe
immunodeficiency , concomitant , prolonged
neurological complications , hospitalization itself ( with prevalence of
nosocomial infection ) , recourse to invasive diagnostic and/or therapeutic procedures , and prior administration of broad spectrum antimicrobial agents , all seem to support
HIV - associated
enterococcal disease ( mostly involving the genito - urinary tract ) . -
pubmed
In nature , the AAL - toxin is the primary determinant of the
Alternaria stem canker disease of
tomato , thus linking apoptosis to this disease caused by
Alternaria alternata f. sp . - pubmed
All
patients presented
maxillary ridge defects . -
pubmed
Toxicity and
carcinogenicity studies were conducted by administering turmeric oleoresin in feed to groups of male and female
F344 / N rats and
B6C3F1 mice for 13 weeks and 2 years . -
pubmed
The final mean
body weight of
males receiving 50,000 ppm was 5 % lower than that of the controls . -
pubmed
Dietary levels of 1,000 , 5,000,10,000 , 25,000 , or 50,000 ppm turmeric oleoresin were estimated to deliver average daily doses of 50 , 250 , 480 , 1,300 , or 2,600 mg / kg
body weight to
males and 60 , 300 , 550 , 1,450 , or 2,800 mg / kg to females . -
pubmed
Hyperplasia of the mucosal epithelium was observed in the cecum and colon of male and female
rats that received 50,000 ppm . -
pubmed
There were no
deaths attributed to turmeric oleoresin and the final mean body
weight gains and final mean
body weights of all exposed groups of male and female
mice were similar to those of the controls . -
pubmed
Dietary levels of 1,000 , 5,000,10,000 , 25,000 , or 50,000 ppm turmeric oleoresin were estimated to deliver average daily doses of 150 , 750 , 1,700 , 3,850 , or 7,700 mg / kg
body weight to
males and 200 , 1,000 , 1,800 , 4,700 or 9,300 mg / kg to females . -
pubmed
The final mean
body weights of all exposed male
rats and female
rats receiving 2,000 and 10,000 ppm were similar to those of the controls . -
pubmed
The final mean
body weights of male and female
rats that received 50,000 ppm were slightly lower ( up to 10&percnt ;) than those of the controls throughout much of the study . -
pubmed
Pathology Findings : Chemical - related
nonneoplastic lesions occurred in the gastrointestinal tract of
rats that received 50,000 ppm . -
pubmed
Males receiving 50,000 ppm had increased incidences of
ulcers ,
hyperplasia , and
hyperkeratosis of the forestomach . -
pubmed
Male and female
rats that received 50,000 ppm had
ulcers , chronic active
inflammation , and
hyperplasia of the cecum . -
pubmed
Male and female
rats that received 50,000 ppm and
male rats that received 10,000 ppm had significantly increased incidences of
sinus ectasia of the mesenteric Iymph node . -
pubmed
The incidences of
clitoral gland adenoma in all exposed groups of female
rats were significantly increased . -
pubmed
Clitoral gland carcinomas occurred in one control female and in four 2,000 ppm females , but not in
females that received 10,000 or 50,000 ppm . -
pubmed
The incidences of clitoral gland
adenoma or
carcinoma ( combined ) in all exposed groups of female
rats were similar ( 6/50 , 16/48 , 15/47 , 16/49 ) and did not increase with exposure level . -
pubmed
The incidence of
clitoral gland hyperplasia was similar among exposed and control groups of female
rats ( 7/50 , 5/48 , 4/47 , 7149 ) . -
pubmed
The mean
body weight of female
mice receiving 50,000 ppm was slightly lower ( up to 12&percnt ;) than that of the controls from about week 25 . -
pubmed
The final mean
body weights of
males that received 50,000 ppm and females that received 10,000 and 50,000 ppm were significantly lower than those of controls . -
pubmed
The final mean
body weights of other exposed groups of male and female
mice were similar to those of the controls . -
pubmed
Pathology Findings : The incidences of
hepatocellular adenoma in male and female
mice receiving 10,000 ppm , but not those in
mice receiving 2,000 or 50,000 ppm , were significantly increased ( male : 25/50 , 28/50 , 35/50 , 30/50 ; female : 7/50 , 8/50 , 19/51 , 14/50 ) . -
pubmed
The number of male and female
mice in the 10,000 and 50,000 ppm groups with multiple
hepatocellular neoplasms was significantly greater than that in the controls . -
pubmed
In contrast to
rats , there were no chemical - related
nonneoplastic lesions of the gastrointestinal tract in
mice . -
pubmed
Three
males that received 2,000 ppm and three
males that received 10,000 ppm had
carcinomas of the small intestine ;
neoplasms of the small intestine were not observed in control males or in
males that received 50,000 ppm . -
pubmed
Female
mice receiving 50,000 ppm had a significantly increased incidence of thyroid gland follicular cell
hyperplasia . -
pubmed
It induced small but significant increases in sister chromatid exchanges and
chromosomal aberrations in cultured
Chinese hamster ovary cells . -
pubmed
There was equivocal evidence of carcinogenic activity of turmeric oleoresin in female
F344 / N rats based on increased incidences of
clitoral gland adenomas in the exposed groups . -
pubmed
There was equivocal evidence of carcinogenic activity of turmeric oleoresin in male
B6C3F1 mice based on a marginally increased incidence of
hepatocellular adenoma at the 10,000 ppm level , and the occurrence of
carcinomas of the small intestine in the 2,000 and 10,000 ppm groups . -
pubmed
There was equivocal evidence of carcinogenic activity of turmeric oleoresin in female
B6C3F1 mice based on an increased incidence of
hepatocellular adenomas in the 10,000 ppm group . -
pubmed
Turmeric oleoresin ingestion was also associated with increased incidences of
ulcers ,
hyperplasia , and
inflammation of the forestomach , cecum , and colon in
male rats and of the cecum in female
rats . -
pubmed
In female
mice , ingestion of diets containing turmeric oleoresin was also associated with an increased incidence of
thyroid gland follicular cell hyperplasia . -
pubmed
[ Variability of antigenic properties of drug - resistant
strains of the
Gonococcus ] . -
pubmed
LIPID COMPONENTS OF BILE FROM
CHOLINE DEFICIENT RATS . -
pubmed
Fifty - two , 13 , and 9
MUD patients were treated with
ATG in a total dose of 8 mg / kg , 6 mg / kg , and 4 mg / kg ( given from days -8 until -4 ) , respectively . -
pubmed
Early age at
EBV infection and lower socioeconomic status have been related to increased
EBV - associated
BL in developing countries . -
pubmed
Our aim was to evaluate the clinicopathologic features and
EBV association of 44 children with
NHL from the state of Rio de Janeiro , situated in the southeast of Brazil . -
pubmed
DNA from fresh
tumor samples and from paraffin - embedded tissues of patients were analyzed by PCR , in which the first reaction included primers for an EBNA-2 common region while the nested reaction amplified the region discriminating between
EBV types 1 and 2 in separate reactions . -
pubmed
EBV was detected in 21 of 29
BLs ( 72 % ) , and type 1 virus infected the majority of
EBV - positive
BLs ( 18/21 ) . -
pubmed
There was a trend for younger age in children with
EBV - positive BL compared to EBV - negative
BL ( median age 4 compared to 6 years , respectively ; p = 0.056 ) . -
pubmed
In conclusion , our study suggests that early
infection with
EBV in the background of a low socioeconomic condition associated with other environmental factors could contribute to
BL in Brazil . -
pubmed
This alarming statistic is partly attributable to lifestyle , and partly due to the genetic factors that make
humans highly susceptible to
atherosclerotic vascular disease . -
pubmed
PATIENTS AND METHODS : All 21
patients who had undergone the IQLO were analyzed for operation time , blood loss , length of hospitalization , intraoperative and
postoperative complications , and radiographic abnormalities . -
pubmed
Chemotherapeutic agents have been used for the treatment of
patients with
osteosarcoma (
OS ) . -
pubmed
However , inherent or acquired resistance to these agents is a serious problem in the management of
OS patients . -
pubmed
The risk of
iodine - induced
thyrotoxicosis in euthyroid
patients receiving
iodine - containing contrast agents is known to be low , but data on this risk in
patients with latent
hyperthyroidism are scarce . -
pubmed
In the 56
patients with TCTU less than 1 % , no case of
iodine - induced
hyperthyroidism occurred within 4 wk after CA . -
pubmed
In the
patients who received prophylactic drugs , two cases of mild
thyrotoxicosis were observed . -
pubmed
Furthermore , two major changes associated to aging :
osteoporosis and
sarcopenia , have been also linked to the development of
frailty in elderly
patients . -
pubmed
In both cases
vitamin D plays an important role since the low levels of this vitamin seen in senior
people may be associated to a
deficit in bone formation and muscle function . -
pubmed
alpha - Lipoic acid induces apoptosis in
human colon cancer cells by increasing mitochondrial respiration with a concomitant
O2 -*-generation . -
pubmed
We determined in
HT-29 human colon cancer cells whether
ALA is able to affect apoptosis , as an important parameter disregulated in
tumour development . -
pubmed
In conclusion , our study provides evidence that
ALA and
DHLA can effectively induce apoptosis in
human colon cancer cells by a prooxidant mechanism that is initiated by an increased uptake of oxidizable substrates into mitochondria . -
pubmed
Osteoporosis in its most common form affects the elderly ( both sexes ) and all racial groups of
human beings . -
pubmed
PIMT - deficient mice manifested neurodegenerative changes concomitant with the accumulation of
L - isoaspartate in the brain . -
pubmed
We discuss here the pathological implications of the formation of
isoaspartate in damaged proteins during neurodegeneration in model
mice and
AD . -
pubmed
Atorvastatin in
patients with
type 2 diabetes mellitus undergoing dialysis . -
pubmed
OBJECTIVE : To investigate the effects of surgically induced
weight loss on exercise capacity in
patients with
morbid obesity (
MO ) . -
pubmed
After
weight loss ,
obese patients performed each workload with lower
oxygen consumption , heart rate ,
systolic arterial pressure , and ventilatory volume ( p & lt ; 0.001 ) . -
pubmed
DISCUSSION : After surgically induced
weight loss , MO
patients markedly improved their exercise capacity . -
pubmed
BACKGROUND : Noninvasive identification of culprit lesions has the potential to improve noninvasive risk stratification in
patients with acute
chest pain . -
pubmed
METHODS : Thirty - seven
patients with
acute coronary syndrome (
ACS ) or
stable angina underwent coronary 16 - slice MDCT and invasive selective angiography . -
pubmed
Differences between culprit lesions in
patients with
ACS and stable lesions in
patients with
ACS or
stable angina were determined . -
pubmed
RESULTS : We analyzed 40 lesions with excellent image quality in 14
patients with
ACS and 9
patients with
stable angina . -
pubmed
Culprit lesions in
patients with
ACS ( n = 14 ) had significantly greater plaque area and a higher remodeling index than both stable lesions in
patients with
ACS ( n = 13 ) and in
patients with
stable angina ( n = 13 ) ( 17.5 + /- 5.9 mm2 vs. 9.1 + /- 4.8 mm2 vs. 13.5 + /- 10.7 mm2 , p = 0.02 ; and 1.4 + /- 0.3 vs. 1.0 + /- 0.4 vs. 1.2 + /- 0.3 , p = 0.04 , respectively ) . -
pubmed
The prevalence of non - calcified plaque was 100 % , 62 % , and 77 % , respectively , and the prevalence of
calcified plaque was 71 % , 92 % , and 85 % , respectively , in culprit lesions in
patients with
ACS and in stable lesions in
patients with
ACS or
stable angina . -
pubmed
CONCLUSIONS : We introduce the concept of noninvasive detection and characterization of
coronary atherosclerotic lesions in
patients with
ACS by MDCT . -
pubmed
We show how guidelines formulated to advise travellers on appropriate chemoprophylaxis for areas of reported
Plasmodium falciparum and
Plasmodium vivax malaria risk can be used to generate crude spatial limits . -
pubmed
Intracranial pressure monitoring in
patients with
acute liver failure : a questionable invasive surveillance . -
pubmed
Coronary artery disease in
patients with
systemic lupus erythematosus . -
pubmed
BACKGROUND : A 24 - year - old
woman with an 11 - year history of
systemic lupus erythematosus presented with exacerbation of chronic
abdominal pain followed by substernal
chest pain . -
pubmed
Twenty
macromastia patients were subjected to free - nipple - graft reduction mammoplasty in combination with inferior pedicled dermaglandular reduction mammaplasty of a total of 40 breasts with this technique between years 2000 and 2004 . -
pubmed
In the present study , we evaluated the efficacy of HbV for improving
stroke - related symptoms induced by
middle cerebral artery ( MCA ) occlusion / reperfusion and an intra - internal carotid arterial injection of
arachidonic acid ( AA ) in
rats . -
pubmed
was administered to
rats immediately after the MCA occlusion , it reduced the
cerebral infarct volumes of the cortex and total of the cortex plus sub - cortex significantly as compared with saline as a vehicle . -
pubmed
Retrobulbar teratoma causing
exophthalmos in a
cat . -
pubmed
A 3 - year female - neutered domestic shorthair
cat presenting with
exophthalmos and an ipsilateral subzygomatic soft tissue mass lesion is described . -
pubmed
A retrobulbar location has not been previously reported in the
cat and should be considered a rare cause of
exophthalmos in this
species . -
pubmed
PATIENTS AND METHODS : Using strict inclusion criteria and a database of 1715 EVT
patients , we identified ten idiopathic ruptured
DCAAs ( 0.6 % ) over a 13 - year period ( 1993 - 2006 ) . -
pubmed
The series comprised six
males and four females with mean age of 64 years and solitary
aneurysms located on posterior inferior cerebellar artery ( five
patients ) , anterior inferior cerebellar artery ( three
patients ) and superior cerebellar artery ( two
patients ) . -
pubmed
One
patient died following a procedure - related re -
bleeding and one
patient required re - treatment after failed endosaccular packing . -
pubmed
Focal
cerebellar infarctions were seen on computed tomography images after EVT in three
patients , only one of whom was symptomatic with transient
dysmetria , which resolved completely during follow up . -
pubmed
Based on the clinical symptoms observed in this
patient , the broad differential diagnostic spectrum of
hyperpigmentation of the nails is briefly reviewed here . -
pubmed
In
individuals who undergo
hydroxycarbamide treatment ,
melanonychia might sometimes be seen as side effect and always has to be differentiated from subungual
malignant melanoma . -
pubmed
They were on triple immunosuppressive therapy and had serum
creatinine level of less than 160micromol / L. Thirty - one
patients ( 39.8 % ) were found to have blood
cholesterol levels & gt ; 6.4 mmol / L. Significant positive correlation was found between
hypercholesterolemia and
cyclosporine blood levels above 200 ng / ml ( p< ; 0.0009 ) . -
pubmed
There was no significant correlation between
cholesterol blood level and the
patient age , sex , presence of
diabetes ,
prednisolone , dose , or treatment with C.-blockers and diuretics . -
pubmed
In conclusion ,
hyper - cholesterolemia is common in stable renal transplant
patients . -
pubmed
The aim of this study was to investigate PPI deficit in relation to the dimensions of
auditory hallucinations in
patients with
schizophrenia or
schizoaffective disorder . -
pubmed
METHOD : PPI of the acoustically elicited eye blink startle response was measured electromyographically in 62
patients with
schizophrenia ( n=55 ) or
schizoaffective disorder ( n=7 ) ( 26 of 62 with current
auditory hallucinations ) and 22 healthy
participants matched , on average , to age and sex of the
patient group . -
pubmed
Hearing voices with a high degree of negative content was associated with high mean startle amplitude in
patients with current
auditory hallucinations . -
pubmed
CONCLUSIONS : Although
auditory hallucinations in
patients with
schizophrenia are theorised to result from impaired monitoring of inner speech , the inability to consciously ignore them appears to be associated with a gating deficit . -
pubmed
In this case series we present history , clinical manifestations , KOH smear , and histopathological findings of a series of four
patients with
crusted scabies . -
pubmed
MATERIALS AND METHODS : MDCT - guided transthoracic needle biopsy ( TNB ) was performed on 84
patients ( 55
men and 29
women ; mean age 65 years ) with suspected
lung neoplasm by using a spiral MDCT scanner with the simultaneous acquisition of six slices per rotation . -
pubmed
METHODS : One hundred six
patients with acute
aneurysmal SAH were randomized to receive either peroral or intravenous
nimodipine treatment . -
pubmed
The
patients were monitored for at least 10 days after
bleeding in terms of delayed
ischemic neurological deficits (
DINDs ) and with daily measurements of blood flow velocities in the middle cerebral arteries by using transcranial Doppler ultrasonography . -
pubmed
Clinical outcome according to the Glasgow Outcome Scale was the same in both groups , and there was no difference in the number of
patients with new
infarctions on MR imaging . -
pubmed
Hypertension is a common clinical disease and a major risk to
human health . -
pubmed
[ Changes in plasma hemostatic parameters under intravascular laser irradiation of blood in
patients with community - acquired
pneumonia ] . -
pubmed
SUBJECTS AND METHODS : One hundred and forty
patients aged 17 to 62 years ( mean 39.5 + /- 8.4 years ) with
CAP were examined . -
pubmed
CONCLUSION : ILIB is an effective method in correcting
hemocoagulative disorders in
patients with
CAP . -
pubmed
METHODS : Retrospective study of case - records of
patients with
intrabronchial mass lesions diagnosed by flexible bronchoscopy , bronchial washings and bronchial biopsy between January 2004 and June 2006 . -
pubmed
Repeat
traumatic brain injury in the juvenile
rat is associated with increased
axonal injury and
cognitive impairments . -
pubmed
Among the enormous population of head - injured
children and young adults are a growing subpopulation who experience repeat
traumatic brain injury (
RTBI ) . -
pubmed
While several
animal models have been proposed to study
RTBI , they have been shown to either produce
injuries too severe , were conducted in adults , involved craniotomy , or failed to show
behavioral deficits . -
pubmed
A closed
head injury model for postnatal day 35
rats was established , and single and repeat
TBI ( 1 - day interval ) were examined histologically for
axonal injury and behaviorally by the novel object recognition ( NOR ) task . -
pubmed
The results from the current study demonstrate that an experimental closed
head injury in the
rodent with low mortality rates and absence of gross pathology can produce measurable
cognitive deficits in a juvenile age group . -
pubmed
Over one in six
persons with
subclinical hypothyroidism progressed to overt
thyroid dysfunction over the 5 - year period . -
pubmed
Furthermore , the misidentification of nontuberculosis mycobacteria (
NTM ) in patients presumably suffering from
tuberculosis results in additional
human and health care costs . -
pubmed
Discussed are the anatomic conditions leading to this
syndrome in these two
patients , the methodology for confirming the diagnosis , and the successful management by partial resection of the transverse processes compressing the vertebral arteries . -
pubmed
Hyperplasia of airway smooth muscle cells ( ASMCs ) is a characteristic change of chronic
asthma patients . -
pubmed
METHODS : Twenty - seven asymptomatic
adults with
flat - arched foot posture were recruited to this study . -
pubmed
To assess the possible risk factors for developing
pain in normospermic adult varicocoele patients , 42 adult
patients with left
painful varicocoele ( group 1 ) and 35 age - matched
patients with left painless
varicocoele ( group 2 ) were recruited to this study . -
pubmed
Tunnel vision and
night blindness in a 52 - year - old
man . -
pubmed
METHODS : A retrospective analysis is performed : 20 consecutive
patients with both
lower extremity pain and
low back pain , with low back counting for at least 30 % of the overall
pain were implanted with a small profile plate type lead , S - Series ( SJM ) , via percutaneous approach . -
pubmed
Patients were asked to rate their back and leg
pain as well as their overall satisfaction and data on quality of life ( QOL ) on a ( 0 - 10 point ) visual analog scale ( VAS ) before and after implantation . -
pubmed
Medication use , functional
pain (
pain when bending forward , moving ) , and
patient satisfaction scores also were collected . -
pubmed
In 17
patients ( 85 % ) a clinically relevant reduction ( defined as reduction of 2 points or 30 % in VAS ) in back
pain was seen , with a mean decrease of 4.3 points ( 2.0 - 10.0 ) or 52 % ( 22 - 100 ) . -
pubmed
Only three
patients had no reduction in
back pain , although they had reduction of their
pain in the lower extremities . -
pubmed
CONCLUSION : Percutaneous implantation of the S - Series plate electrodes using a 10 gauge epidural needle combines the advantages of a minimal invasive technique with the possibility to cover the back area supplementing leg coverage in 85 % of the
failed back surgery syndrome patients . -
pubmed
There has been significant progress towards guinea worm eradication , and the control of
leprosy and
human African
trypanosomiasis . -
pubmed
Extract from
Dioscorea batatas ameliorates
insulin resistance in
mice fed a high - fat diet . -
pubmed
The aim of this study was to investigate whether
Dioscorea batatas ( DB ) extract attenuates high - fat diet ( HFD)-induced
insulin resistance in the visceral adipose tissues of
mice , and by what mechanism(s ) . -
pubmed
Mice were fed a HFD for 4 weeks to induce the early development of
insulin resistance . -
pubmed
The DB extract was administered to
mice fed a HFD by oral gavage at a dose of 100 mg / kg
body weight daily for 7 weeks . -
pubmed
PATIENTS : From March 2009 to January 2011 , 26 consecutive
patients ( 19
men and 7
women ) with a median age of 63 ( range , 49 - 79 ) years with
hepatocellular carcinoma were recruited . -
pubmed
Five ( 19 % ) of the
patients had recurrent
hepatocellular carcinoma after previous treatment . -
pubmed
Recurrent
tumours were noted in 11 ( 42 % ) of the
patients ( 5 were local , 2 were remote , and 4 were multifocal ) after a median follow - up of 14 ( range , 4 - 26 ) months . -
pubmed
The failure rate for local disease control was 23 % , and was 14 % if
patients with recurrent
hepatocellular carcinoma were excluded . -
pubmed
This study aimed at assessing the efficacy and safety of biweekly
oxaliplatin in combination with continuous infusional
5 - fluorouracil and
leucovorin ( modified FOLFOX regimen ) in
patients with advanced small bowel
adenocarcinoma (
SBA ) . -
pubmed
All
patients were evaluable for efficacy and
toxicity . -
pubmed
Grade 3 toxicities included
neutropenia ( 12.1 % ) ,
thrombocytopenia ( 3.0 % ) ,
nausea ( 6.1 % ) ,
vomiting ( 3.0 % ) ,
diarrhea ( 3.0 % ) ,
peripheral neuropathy ( 9.1 % ) , and
fatigue ( 3.0 % ) , and grade 4 toxicities occurred in none of the
patients . -
pubmed
The modified FOLFOX regimen is highly active and well tolerated as first - line chemotherapy for advanced
SBA patients . -
pubmed
METHODS : We retrospectively reviewed
stroke patients with
sMLI or
SLI in a consecutively collected
stroke registry with a predefined long - term clinical follow - up . -
pubmed
RESULTS : Of the 548 acute
ischemic stroke patients , sMLI was found in 23 ( 13.5 % ) and
SLI in 148 ( 86.5 % ) . -
pubmed
Preclinical studies with non - replicating
herpes simplex virus ( HSV)-based vectors injected into the skin to transduce neurons in the dorsal root
ganglion have demonstrated efficacy in reducing -
pain related behaviors in animal models of
inflammatory pain ,
neuropathic pain , and
pain caused by
cancer , and in preventing progression of
sensory neuropathy caused by toxins , chemotherapeutic drugs or resulting from
diabetes . -
pubmed
Successful completion of the first phase 1 clinical trial of
HSV - mediated gene transfer in
patients with intractable
pain from
cancer has set the stage for further clinical trials of this approach . -
pubmed
In our report , we explored the pharmacokinetic , pharmacodynamic , and antitumor properties of
MLN0905 in
DLBCL xenograft models grown in
mice . -
pubmed
The antitumor activity of
MLN0905 was evaluated in three
human subcutaneous
DLBCL xenograft models ,
OCI LY-10 ,
OCI LY-19 , and
PHTX-22L ( primary
lymphoma ) . -
pubmed
The antitumor activity of
MLN0905 was also evaluated in a disseminated xenograft (
OCI LY-19 ) model to better mimic
human DLBCL disease . -
pubmed
A 62 - year - old
man was referred to our center for
fracture of the left clavicle because of a fall , and he had a sudden
seizure during admission . -
pubmed
EBV - encoded RNA was negative for
tumor cells . -
pubmed
During the daytime , we interrupted the sedatives and analgesics unless the
patient complained of
discomfort . -
pubmed
CONCLUSIONS : In mechanically ventilated
patients , nighttime infusion of
dexmedetomidine preserved the day - night cycle of sleep but induced severely disturbed sleep architecture without evidence of
SWS or REM sleep . -
pubmed
RESULTS : Of 41
children enrolled , relative
AVP deficiency was present in 13 ( 32 % ) . -
pubmed
Initial combination therapy reduces the risk of cardiovascular events in
hypertensive patients : a matched cohort study . -
pubmed
AML cells are differentially sensitive to chemotherapy treatment in a
human xenograft model . -
pubmed
Mice treated with an optimized 5 - day induction protocol showed transient
weight loss , short - term reduction of peripheral blood cell and platelet counts , and slight
anemia . -
pubmed
AML cells showed significantly increased sensitivity to
doxorubicin - containing therapy compared with
murine BM cells . -
pubmed
Although early treatment could result in some cures ,
mice with significant
leukemia grafts were not cured by using induction therapy alone . -
pubmed
We report a case of a life - long non - smoker , 54 years old
woman who presented these symptoms associated with
bronchiectasis secondary to recurrent inhalation
pneumonia , hypercapnic
respiratory failure , and
central sleep apnea (
CSA).CSA was first unsuccessfully treated with nocturnal c - PAP . -
pubmed
We suggest that in
patients with
type I ACM the presence of pulmonary manifestations aggravating other respiratory disturbances including
sleep disordered breathing (
SDB ) should be actively investigated . -
pubmed
These results show that
infection with arg(- )
L. - pubmed
A visual analog scale ( VAS ) was used to quantify the amount of
pain ,
swelling , and
bleeding in the
patients . -
pubmed
In addition to maintaining the metabolic demands of the
individual in the short term , levels of energy intake must also maintain and defend
body weight over longer periods . -
pubmed
Early and late outcomes of hybrid endovascular and open repair procedures in
patients with
peripheral arterial disease . -
pubmed
PATIENTS AND METHODS : Consecutive
patients with multilevel
arterial disease who underwent single session hybrid procedures were analyzed depending on the type of
ischaemia and the type of revascularization . -
pubmed
Regional and overall aortic function in nondiabetic
individuals with
insulin resistance and normal
glucose tolerance . -
pubmed
OBJECTIVE : The objective of the study was to define the overall and regional aortic function as well as the changes of aortic function over time in nondiabetic
individuals with
insulin resistance and a normal oral
glucose tolerance test ( OGTT ) . -
pubmed
All
infections occurred in
patients who had received patellar resurfacing . -
pubmed
Effects of
dutasteride on
lower urinary tract symptoms and general health in
men with
benign prostatic hypertroplasia and
hypogonadism : a prospective study . -
pubmed
INTRODUCTION : We investigated the effects of the relative increase in
testosterone by
dutasteride administration in
patients with
benign prostatic hyperplasia and
hypogonadism on urinary symptoms or
androgen - responsive general health . -
pubmed
All
patients responded to the questionnaires : International prostatic symptom score ( IPSS ) ,
Overactive Bladder Symptom score ( OABSS ) . -
pubmed
We present a case report of a 74 - year old female
patient with the clinical diagnosis of
transient ischemic attack (
TIA ) in the vertebro - basilar ( VB ) circulation , in whom we found bilateral variation of the extracranial section of vertebral arteries on ultrasound , on the left side to the extent of kinking . -
pubmed
Screening for this innate response predicted accurately in which
mice recurrence would occur . -
pubmed
[ Relationship between residual milk and clinical
mastitis in dairy
cattle ] . -
pubmed
Mastitis in
cattle is an
infection of the mammary gland caused by
infection , toxins and/or
trauma . -
pubmed
We aim to examine the association between rapid eye movement ( REM ) AHI and QOL scores in
children with
sleep - disordered breathing (
SDB ) . -
pubmed
SUBJECTS AND METHODS :
Children between 3 and 16 years of age with suspected
SDB who were undergoing PSG were eligible . -
pubmed
The content of
oleanolic and ursolic acid in the extracts were determined , and different samples were screened for cellular
cytotoxicity and virus inhibition using a
HCV cell culture
infection system . -
pubmed
METHODS : Fifty - one
patients with
CLBP and 56
patients with
CNP participated . -
pubmed
Reply :
Endometrial injury and reproductive outcomes : there 's more to this story than meets the
horse 's blind eye . -
pubmed
In addition , a number of studies utilizing optogenetic strategies or transgenic
mouse lines have begun to examine specific central amygdala neurocircuit dynamics and neuronal subpopulations to better understand overall central amygdala neurocircuitry and the role of neuronal subtypes in mediating
anxiety - like behaviors . -
pubmed
Though the initial brain imaging showed extensive involvement of the white matter with multiple
haemorrhagic foci , the
patient improved spontaneously with no specific therapy . -
pubmed
METHODS : Sixty - eight
Candida isolates (
37 albicans and 31
non - albicans isolates ) recovered from corneal scrapings submitted to rule out
microbial keratitis , during the years 2005 to 2011 , at the Bascom Palmer Eye Institute , were examined in this study . -
pubmed
Mouse models are common tools for examining
post - traumatic osteoarthritis (
OA ) , which involves
cartilage deterioration following
injury or stress . -
pubmed
One challenge to current
mouse models is longitudinal monitoring of the
cartilage deterioration in vivo in the same
mouse during an experiment . -
pubmed
Future studies may use this reporter
mouse to advance basic and preclinical studies of
murine experimental
OA with applications in synovial joint biology , disease pathogenesis , and drug delivery . -
pubmed
From October 2013 to date , approximately 1,000 outbreaks of
porcine epidemic diarrhoea virus (
PEDV ) have occurred in Japan . -
pubmed
Phylogenetic analysis indicated that the Tottori2
PEDV strain might have been derived from the current
PEDV strains circulating in domestic pigs . -
pubmed
Moreover , the Tottori2
PEDV strain was successfully isolated in
Vero cells by serial passage . -
pubmed
The incorporation of the PSAD into risk assessments might provide additional prognostic information and identify some patients in whom active surveillance would be appropriate in
patients with
IRPCa . -
pubmed
OBJECTIVE : Analyzing the quality of sleep of
hypertensive patients registered in the national registration system and monitoring of
hypertensive patients . -
pubmed
RESULTS : The prevalence of poor sleep quality among respondents ( 156
hypertensive patients ) and high rates of using medication for sleeping ( 106
hypertensive patients ) was observed . -
pubmed
BACKGROUND AND OBJECTIVES :
Insulin resistance has been associated with
cardiovascular disease in peritoneal dialysis
patients . -
pubmed
Patients were categorized according to dialysate to plasma
creatinine ratio at 4 hours , 3.86 % peritoneal equilibration test , and
obesity parameters . -
pubmed
RESULTS :
Obesity was present in 49 % of
patients according to rel . -
pubmed
A total of 18
patients ( 35.3 % ) who had
insulin resistance presented with higher LAR and rel . -
pubmed
CONCLUSIONS :
Insulin resistance in nondiabetic peritoneal dialysis
patients is associated with
obesity and LAR independent of
glucose absorption and small - solute transport status . -
pubmed
Compound 13d , having good in vitro ADME profile and moderate oral bioavailability in
mice , showed potent anti - inflammatory activity against hapten - induced
contact hypersensitivity reaction in
mice following topical and oral administration . -
pubmed
MATERIALS AND METHODS : We conducted a prospective randomized study for a period of 2 years from September 2007 to August 2009 in 109 untreated
patients of
squamous cell carcinoma of head and neck with histologically confirmed diagnosis and no evidence of distant
metastasis . -
pubmed
CONCLUSION : Use of 6 fractions per week instead of 5 fractions per week is feasible , tolerable , and results in a better outcome in the
patients of
head and neck cancers . -
pubmed
We conclude that liver resection may improve the short- and long - term survival of carefully selected intermediate
HCC patients , and the procedure may be safely performed in the management of intermediate
HCC . -
pubmed
The effect of 1 mg
folic acid supplementation on clinical outcomes in female
migraine with aura patients . -
pubmed
We have previously provided evidence that reduction of
homocysteine with a vitamin supplementation can reduce the occurrence of
migraine in
women . -
pubmed
METHODS : This was a 6 month randomised , double blinded placebo controlled trial of daily vitamin supplementation containing 1 mg of
folic acid , 25 mg of
Vitamin B6 and
Vitamin B12 , on reduction of
homocysteine and the occurrence of
migraine in 300 female
patients diagnosed with
migraine with aura . -
pubmed
The treatment group did not show a significant decrease in the percentage of
participants with high
migraine disability , severity or frequency at the end of the 6 month intervention ( P & gt ; 0.1 ) . -
pubmed
Nineteen percentage of
children treated with
ondansetron continued
vomiting after the administration of the therapy vs 93 % of
children who received traditional therapy ( P & lt ; 0.05 , relative risk = 0.2 ) . -
pubmed
Moreover , we asked whether increased accumulation of
oxysterols characterizes the adipose cells of
obese patients with
type 2 diabetes (
T2D ) ( OBT2D ) compared with lean , nondiabetic controls ( CTRLs ) . -
pubmed
Co - administration of
thioperamide and
oxytocin significantly amplified
hypophagic effect of
oxytocin in
chickens ( P & lt ; 0.001 ) . -
pubmed
In addition ,
ICI 118,551 attenuated
hypophagic effect of
oxytocin ( P & lt ; 0.001 ) ; while
famotidine ,
prazosin ,
yohimbine ,
metoprolol and
SR59230R had no effect on
oxytocin- induced food intake in FD3
broiler chickens . -
pubmed
In cases of
cyst fenestrations postoperatively , the
cyst volume was significantly reduced in all
patients by mean of 47 % . -
pubmed
METHODS : In 2009 , a retrospective analysis was performed at one tertiary referral center for 953
patients diagnosed with
tuberculosis . -
pubmed
Long - term outcomes of
infliximab treatment and predictors of response in 195
patients with
ulcerative colitis : a hospital - based cohort study from Korea . -
pubmed
BACKGROUND : Large - scale studies regarding the long - term efficacy of
infliximab ( IFX ) treatment in non - Caucasian
patients with
ulcerative colitis (
UC ) are lacking . -
pubmed
STUDY : We analyzed the long - term outcomes of IFX in 195 Korean
UC patients who received scheduled IFX treatments at Asan Medical Center . -
pubmed
Multiple Subpial Transections for Medically Refractory
Epilepsy : A Disaggregated Review of
Patient - Level Data . -
pubmed
Data regarding
seizure outcome ,
patient demographics ,
seizure type , surgery type , and complications were extracted and analyzed . -
pubmed
Complications were frequent , with transient mono- or
hemiparesis affecting 19.8 % of
patients , transient
dysphasia 12.3 % , and permanent
paresis or
dysphasia in 6.6 % and 1.9 % of
patients , respectively . -
pubmed
Acute kidney injury (
AKI ) is a common and serious condition frequently encountered in hospitalized
patients . -
pubmed
Differences in
Neurocognitive Impairment Among
HIV - Infected Latinos in the United States . -
pubmed
OBJECTIVES :
Human immunodeficiency virus (
HIV ) disproportionately affects Hispanics / Latinos in the United States , yet little is known about
neurocognitive impairment (
NCI ) in this group . -
pubmed
METHODS : We prospectively studied 286
patients with
AIS who were admitted within 24 h after the onset of symptoms . -
pubmed
Evaluation of Serum Symmetric
Dimethylarginine Concentration as a Marker for Masked
Chronic Kidney Disease in
Cats With
Hyperthyroidism . -
pubmed
Currently , there is no clinical test that can reliably predict which
hyperthyroid cats have concurrent azotemic
CKD that will become apparent after treatment of the
hyperthyroidism . -
pubmed
OBJECTIVES : To investigate serum
symmetric dimethylarginine (
SDMA ) concentration as a potential marker of masked
azotemia in untreated
hyperthyroid cats . -
pubmed
ANIMALS : Two hundred and sixty - two
hyperthyroid cats and 206 aged - matched , clinically normal
cats . -
pubmed
RESULTS : No
hyperthyroid cats were
azotemic before treatment , but 42 ( 16 % ) became
azotemic when rechecked at 4 - 8 months ( median , 6 months ) after 131 I treatment ; of these , 14 had high
SDMA concentrations before treatment . -
pubmed
As a diagnostic test for pre - azotemic ( masked )
CKD in untreated
hyperthyroid cats ,
SDMA showed a sensitivity of 33.3 % and specificity of 97.7 % . -
pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : Finding a high serum
SDMA concentration in a
hyperthyroid cat can help predict development of
azotemia after treatment . -
pubmed
The test has high diagnostic test specificity ( few false - positive results ) but relatively low sensitivity ( fails to predict
azotemia in most
hyperthyroid cats ) . -
pubmed
Cheese - derived
SFA and individual
SFA that are commonly found in
cheese , were significantly related to lower
T2D risks . -
pubmed
Due to the increased detection of O113
strains and their relationship with clinical cases , which emphasizes the importance of this serogroup as an emerging pathogen , our aim was to determine the characteristics of
STEC O113 : H21 strains circulating in bovine
cattle and retail meat from Argentina . -
pubmed
IMPORTANCE The high - risk
human papillomaviruses (
HPVs ) are the etiological cause of
cervical cancer and the most common
sexually transmitted infection . -
pubmed
While the majority of
infections may be asymptomatic or cause only benign lesions , persistent
infection with the oncogenic high - risk
HPV types may lead to serious diseases , such as
cervical cancer ,
anogenital carcinoma , or
head and neck oropharyngeal squamous cell carcinoma . -
pubmed
A case study based on Orthopoxviruses ( Variola , Monkeypox , and
Ectromelia viruses ) demonstrates a considerable increase in the fluorescence signal ( up to 100 - fold ) when several oligonucleotide probes are printed to one
spot . -
pubmed
A
cerebral ischemic / reperfusional ( CI / R ) injury model in
mice was implemented to elucidate the neuronal protective mechanism(s ) of
P7C3 . -
pubmed
Anticancer studies demonstrated the in vitro
cytotoxicity value of
Cu - NPLs against tested
human colon cancer Caco-2 cells ,
human hepatic cancer HepG2 cells and
human breast cancer Mcf-7 cells . -
pubmed
To conclude ,
Cu - NPLs are promising in electronic devices and they possess a potential anticancer application for some
human cancer therapy as well . -
pubmed
We previously isolated a
monocrotophos - degrading
strain Starkeya sp . - pubmed
METHODS : We used 2191
NPC patients as a training set and 414
patients separately as an independent , external validation cohort . -
pubmed
Massive amounts of medical and health resources have been devoted to
patients with
osteoporosis and
osteoporosis - related
fractures . -
pubmed
Due to the emerging resistance by the parasites and mosquitoes for the current medications and insecticides , respectively , the
malaria free
human world can be attained only by the novel design and development of new anti - malarial drugs . -
pubmed
miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of
Alzheimer ' s Patients . -
pubmed
ROC analysis indicated that measurement of miR-132 - 3p in neurally - derived plasma EVs showed good sensitivity and specificity to diagnose
AD , but did not effectively separate
individuals with
AD -
MCI from controls . -
pubmed
Moreover , when we measured the levels of a related miRNA , miR-212 , we found that this miRNA was also decreased in neural EVs from
AD patients compared to controls . -
pubmed
Regional and temporal miRNAs expression profile in a transgenic
mouse model of
tauopathy : implication for its pathogenesis . -
pubmed
In the current paper , we assessed the miRNA expression profile at different age time points and brain regions in a relevant
mouse model of
human tauopathy , the hTau
mice , in relationship with the development of
behavioral deficits and tau neuropathology . -
pubmed
The expression of platelet - derived growth factor receptor alpha - positive cells in the stenotic tissue of
ureteropelvic junction obstruction in
children : . -
pubmed
Purpose : The
patient - reported outcome measure ( PROM)-based evaluation in
lumbar degenerative disc disease (
DDD ) is
today 's gold standard but has limitations . -
pubmed
Patients with
LEMD had slightly higher disability ( ODI 52.8 vs. 48.2 , p=0.025 ; RMDI 12.6 vs. 11.3 , p=0.034 ) but similar
pain and hrQoL scores . -
pubmed
OFI T - scores were significantly higher in
patients with
LEMD ( 144.2 vs. 124.3 , p=0.006 ) . -
pubmed
The draft genomes of three fungal clinical isolates of
Madurella mycetomatis from patients with
mycetoma are presented . -
pubmed
A middle - aged
woman was hospitalised for generalised , painful
skin lesions 6 weeks after a successful double - lung transplant . -
pubmed
Patients were followed - up until the delivery and final outcomes of pregnancy were recorded in terms of
preterm delivery and SGA births . -
pubmed
Here , we describe a case in which a
patient developed extensive anal epithelial proliferations resembling
condylomata acuminata , after starting
vemurafenib treatment . -
pubmed
OBJECTIVE : We aim to conduct a systematic review and meta - analysis of observational studies on the association between
LAN exposure and risk of
obesity in
human subjects . -
pubmed
Suprapubic cystostomy during renal transplantation in a
patient with a
urethral stricture after
hypospadias surgery : A case report . -
pubmed
Conclusion : A cystostomy may be one strategy for renal transplantation
patients with a
urethral stricture . -
pubmed
As - sessment of the antimicrobial activity of the conjugate revealed that attachment of the salmochelin mimic resulted in decreased potency , compared to
ciprofloxacin , against two
Escherichia coli strains ,
K12 and
Nissle 1917 , in both
iron - replete and deplete conditions . -
pubmed
Collectively , our results suggest that telomere shortening could represent a mechanism that moderates the proliferative capacity of
human hippocampal progenitors , which may subsequently impact on
human cognitive function and
psychiatric disorder pathophysiology . -
pubmed
Questionnaire responses from the
pig keepers in this area highlighted the need to implement basic biosecurity measures in smallholder
pig keepers to prevent outbreaks of
ASF in South Africa . -
pubmed
Background : The study was aimed to evaluate the safety and efficacy of
fentanyl and
pethidine on the sedative quality of
patients who underwent phacoemulsification
cataract surgery with
Propofol . -
pubmed
Demographic characteristics , hemodynamic parameters before , during , and after the operation , sedation and
pain scores , and
patients ' and surgeons ' satisfaction scores were compared in the two studied groups . -
pubmed
METHODS : We conducted a prospective case - control study in an inception cohort of 552
patients ( 328
IBD , 224 non - IBD ) , profiling proteins recruited across 6 centres . -
pubmed
These findings have profound implications for the development of
murine models of
human inflammatory disorders such as
infection and
sepsis . -
pubmed
What are the risk factors for
surgical site infection in
HIV positive
patients receiving open reduction and internal fixation of
traumatic limb fractures ? -
pubmed
We questioned ( 1 ) what is the proportion with
SSI in
HIV positive patients receiving open reduction and internal fixation ( ORIF ) of
traumatic limb fractures ; ( 2 ) what are the independent risk factors for SSI of
HIV positive patients with
traumatic limb fractures who received ORIF . -
pubmed
Data of
HIV positive adult patients with
traumatic limb fractures treated by ORIF were extracted from the electronic medical records , including the demographic information , characteristics of
fractures , treatment - related variables and indexes of laboratory examination . -
pubmed
RESULTS : A total of 26
patients developed
SSI in this study , the overall proportion was 10.6 % ( 95 % CI=7.2%-15.3 % ) . -
pubmed
CONCLUSION : We recommend that orthopedic surgeons assess immunosuppression and nutritional status of
HIV positive
patients rigorously and optimize the perioperative strategy of supplementary to reduce the risk of
SSI . -
pubmed
Methods : Cell function tests were performed to observe the inhibitory effect of
cynaropicrin on
human CRC cells (
RKO ,
HCT116 , and
DLD-1 ) . -
pubmed
Results :
Cynaropicrin significantly reduced the survival ability of
human CRC cells and promoted apoptosis in a dose - dependent manner . -
pubmed
PARTICIPANTS :
Adults with and without
TSCI . -
pubmed
Characteristics of the maternal lymphoid response of
mice to paternal
strain antigens induced by homologous pregnancy . -
pubmed
Mice mated with H-2 incompatible males were shown to have an increased frequency of specific allocluster - forming spleen cells to paternal
strain erythrocytes . -
pubmed
Peripheral blood leukocytes ( PBL ) from
patients with
rheumatoid arthritis (
RA ) and from control subjects were exposed to rheumatoid and osteoarthritic synovial membrane extracts . -
pubmed
Pulmonary angiography was performed in 125
patients with suspected
pulmonary embolism . -
pubmed
Balloon - occlusion angiography improved image quality and contributed substantially to the radiographic diagnosis of
pulmonary embolism in most
patients . -
pubmed
[ Long - term follow - up of
patients with disorders of intraventricular conduction in the acute phase of
myocardial infarct ] . -
pubmed
A light microscopic study of
bovine peripheral nerve sheath tumours . -
pubmed
Peripheral nerve sheath tumours from 66
cattle were classified as
schwannomas and
neurofibromas . -
pubmed
Bovine neurofibromatous tissue probably represents a
dysplasia whilst
bovine schwannomas are true neoplastic growths . -
pubmed
Bovine schwannomas probably develop from neurofibromatous nerve and the two entities may represent parts of a single pathological condition . -
pubmed
Hearing loss in renal dialysis and renal transplant
patients occurs quite frequently . -
pubmed
Sepsis was diagnosed in 18
patients , that made 1.7 per cent to a total number of observations . -
pubmed
Among these
septic patients 8
patients died . -
pubmed
Protooncogene activation in spontaneously occurring and chemically induced rodent and
human lung tumors . -
pubmed
Characteristics and kinetics of subzero
chilling injury in
Drosophila embryos . -
pubmed
and in the
rat chronic gastric fistula model . -
pubmed
The new
anthracycline analogue ,
4 '- iodo-4 '- deoxydoxorubicin (
I - DOX ) , was administered at 70 mg / m2 as first chemotherapy in 61
patients with advanced
NSCL ( 19 ) , colon ( 20 ) and
breast cancers ( 22 ) . -
pubmed
Partial responses were observed in 6 % of the
patients with
NSCL , in 5.5 % of those with colon and in 10 % of those with
breast cancers . -
pubmed
The main
toxicity was a selective
granulocytopenia characterized by a duration of about 1 week , and a high inter -
patient variability . -
pubmed
Although the biological function of the F alloantigen is unknown , the immune response to F has been extensively studied as a
murine model of tolerance and
autoimmunity . -
pubmed
The immune response to the allotypic form is restricted to
mouse strains of I - Ak. -
pubmed
The
Epstein - Barr virus (
EBV ) is associated with distinct forms of
human lymphoid malignancies , including the endemic ( eBL ) and sporadic forms of
Burkitt ' s lymphoma (
sBL ) and
acquired immunodeficiency syndrome - associated
non - Hodgkin lymphoma (
AIDS - NHL ) . -
pubmed
However , whether
EBV has a pathogenetic role in these
tumors or is a passenger virus has not been conclusively demonstrated . -
pubmed
Toward this end we analyzed the structure of the heterogeneous genomic termini of
EBV as markers of
clonal infection in a panel of
eBL ( 11 cases ) ,
sBL ( 9 cases ) , and
AIDS - NHL ( 10 cases ) biopsies . -
pubmed
A 49 - year - old
man with
aseptic meningitis and multiple
cranial neuropathies . -
pubmed
Myocarditis accompanies sublethal mouse
cytomegalovirus ( MCMV ) infection in susceptible BALB / c
mice and persists beyond the acute phase of
infection , in the absence of demonstrable virus
antigen but in the continuing presence of autoantibodies to cardiac muscle . -
pubmed
Increasing the virus dose given to C57BL/10
mice resulted in slight increases in titres of anti - myosin antibody ; however , the peak antibody titres did not approach those of BALB / c
mice and persisting
myocarditis did not develop . -
pubmed
Clinical validity of a normal perfusion lung scan in
patients with suspected
pulmonary embolism . -
pubmed
The objective of this study was to test the safety of withholding anticoagulant therapy in
patients with clinically suspected
pulmonary embolism who have normal perfusion lung scans , regardless of the clinical manifestations . -
pubmed
Anticoagulant therapy was withheld or withdrawn in 515 consecutive
patients except in patients in whom
deep - vein thrombosis was detected . -
pubmed
Only three of the 515
patients had symptomatic
venous thromboembolism on follow - up . -
pubmed
It is safe to withhold anticoagulant therapy in
patients with suspected
pulmonary embolism and normal perfusion scans , regardless of the clinical manifestations . -
pubmed
To determine the potential utility of antigen - specific immune complex analysis , we developed a competitive enzyme - linked immunosorbent assay utilizing polyclonal
human antibody to detect
tumor - associated antigen - specific immune complexes . -
pubmed
Sera from 10 normal
volunteers and 19
patients with recurrent
melanoma were studied . -
pubmed
Patients with recurrent
melanoma had a mean + /- SD percent inhibition of 27.6 % + /- 29.8 % in contrast to normal
individuals with a mean value of 8.4 % + /- 17.8 % . -
pubmed
Utilizing MAb JSI , we developed a " sandwich " enzyme - linked immunosorbent assay and studied sera from 45 normal
volunteers and 44
patients with
cancer with recurrent
melanoma . -
pubmed
The mean + /- SD percent maximum binding for normal
subjects was 4.9 % + /- 7.7 % in contrast to sera from
patients with
melanoma who had a mean of 38.3 % + /- 33.3 % . -
pubmed
Serial analysis of four
patients with
melanoma with
tumor - associated antigen - specific immune complexes demonstrated the presence of
tumor - associated antigen - specific immune complexes up to 12 years prior to clinical
recurrence . -
pubmed
The effect of repeated external cephalic version , performed at between 33 and 40 weeks gestation , on presentation at delivery was studied in a randomized controlled trial comprising 180 pregnant
women with
breech presentation . -
pubmed
Cerebral haemorrhage in a pregnant
woman with a
multiple endocrine neoplasia syndrome (
type 2A or
Sipple ' s syndrome ) . -
pubmed
We present the case history of a 30 - yr - old
woman who suffered a
cerebral haemorrhage toward the end of pregnancy ( at 35 wk ) . -
pubmed
Effects of
phenobarbital and secondary
bile acids on liver , gallbladder , and
pancreas carcinogenesis initiated by
N - nitrosobis ( 2 - hydroxypropyl ) amine in
hamsters . -
pubmed
[ The survival rate of primary molar fillings in
schoolchildren in relation to increase in
caries and
caries prevention ] . -
pubmed
Malachite green therapy of
proliferative kidney disease in
rainbow trout : field trials . -
pubmed
The results of a series of experiments to investigate the use of the
arylmethane dye ,
malachite green , for the control of
proliferative kidney disease in
rainbow trout (
Salmo gairdneri Richardson ) are described . -
pubmed
The epidemiology of
diplostomiasis in farmed
rainbow trout from north - east Scotland . -
pubmed
Experiments using caged fish indicated that
diplostomiasis was confined to certain areas of the farm only and that the
infection rate of
rainbow trout with
D. - pubmed
The results of the study indicated that it is possible by regular cleaning and use of molluscicides to keep the intensity of
diplostomiasis at such a level that
rainbow trout do not become severely affected . -
pubmed
However , as with other
parasitic diseases , a combination of control methods will probably be required to eradicate the disease completely from
trout farms . -
pubmed
Effects of
2 - deoxy - D - glucose on glycolysis , proliferation kinetics and radiation response of
human cancer cells . -
pubmed
[ The cytology of some transplanted
tumors in the
hamster cheek pouch ] . -
pubmed
Bovine hyperkeratosis . -
pubmed
Experimental relief of
spasticity in the
cat by lumbosacral radio - frequency cordotomy . -
pubmed
[ Changes in the electrocardiogram of
rats under normothermia and
hypothermia caused by the action of a mediator and
catecholamine ] . -
pubmed
Polysomes were isolated from an enterotoxigenic
strain of
Clostridium perfringens during vegetative growth and at 1 - h intervals after transfer into Duncan - Strong sporulation medium . -
pubmed
Endoscopic electrocoagulation was considered in 69
patients with active
gastroduodenal bleeding including 60
patients with
peptid ulcer . -
pubmed
Six
children in whom an
intussusception was diagnosed on a small bowel follow - through examination are presented . -
pubmed
This domain , which begins at the
amino - terminus and ends at residue 415 , is a major autoantigen in
human autoimmune thyroid disease . -
pubmed
Tissues were surgically obtained from
epileptic patients with
hippocampal sclerosis and compared with specimens from
patients with
seizures originating from
temporal lobe tumors and autopsy controls . -
pubmed
Enhanced
45Ca2 + efflux in cultured vascular smooth muscle cells from spontaneously
hypertensive rats . -
pubmed
In the present study we have compared these two
Ca2 + effluxes in cultured aortic smooth muscle cells derived from spontaneously
hypertensive rats ( SHR ) and Wistar - Kyoto normotensive
rats ( WKY ) . -
pubmed
To determine the spectrum of
systemic diseases associated with pauci - immune necrotizing crescentic
glomerulonephritis , we have analysed extra - renal manifestations , occurrence of
extra - glomerular vasculitis and incidence and specificity of antinuclear cytoplasmic antibodies ( ANCA ) in 40
patients selected only on renal histological criteria . -
pubmed
Among the 33
patients with suspected or established
vasculitis , 13 had presumed or biopsy - proven
Wegener ' s granulomatosis , three had a macroscopic form of
polyarteritis nodosa and 17 could not be adequately classified . -
pubmed
Seventy - three
hypertensive patients , aged 65 and over , entered the study . -
pubmed
The first goal of this clinical study was to define
MOF ; the second was to assess the typical onset , sequence , and pattern of
MOF ; and the third was to define certain risk factors for the development of
MOF in 342 multiple
trauma patients . -
pubmed
Patients with
dermatitis herpetiformis , similar to patients with
coeliac disease not adhering to a gluten free diet , seem to have increased risk for
lymphoma . -
pubmed
AIMS : This study looked at the occurrence of
malignancy and survival of
patients with
dermatitis herpetiformis and compared the results with those seen in patients with
coeliac disease or in the general population . -
pubmed
PATIENTS : A total of 305 adult
patients with
dermatitis herpetiformis diagnosed at the University Hospital of Tampere in 1970 - 1992 were studied . -
pubmed
A control group comprised 383 adult
patients with
coeliac disease , 81 % of them adhered to a gluten free diet , 6 % had a normal diet , and in 13 % the diet history remained unknown . -
pubmed
METHODS : The occurrence of
malignant diseases and survival of the
patients were assessed up to the end of 1993 . -
pubmed
RESULTS : Thirteen ( 4.3 % )
patients with
dermatitis herpetiformis developed 14
malignant disorders during the follow up ( SIR 1.25 ; 95 % confidence intervals 0.68 to 2.09 ) . -
pubmed
A
non - Hodgkin ' s lymphoma occurred in four
patients with
dermatitis herpetiformis , significantly more than expected ( SIR 10.3 ; 2.8 - 26.3 ) . -
pubmed
Thirteen ( 4.3 % )
patients with
dermatitis herpetiformis died during the follow up but there was no increased general mortality . -
pubmed
In
coeliac disease , 13 ( 3.4 % )
patients developed
malignancy ( SIR 1.16 ; 0.62 to 1.97 ) , 31 ( 8.1 % ) patients died but the survival rate did not differ from that in the general population . -
pubmed
CONCLUSIONS : The incidence of
non - Hodgkin ' s lymphoma was significantly increased in
patients with
dermatitis herpetiformis . -
pubmed
The results also confirm that the
patients with
dermatitis herpetiformis treated mainly with a gluten free diet have no increased general mortality . -
pubmed
However ,
oestrogen therapy may often not be appropriate because of clinical contraindications , side effects or
patient concerns regarding the risk of
breast cancer . -
pubmed
METHODS : Data for 59,876
cancer - registry
patients aged 50 - 79 were analysed . -
pubmed
In cases of
endophthalmitis all therapeutical options have to be performed as soon as possible to save the
patient 's eye and sight . -
pubmed
Potent antiretroviral therapy can reduce
human immunodeficiency virus (
HIV ) in plasma to levels below the limit of detection for up to 2 years , but the extent to which viral replication is suppressed is unknown . -
pubmed
Infection of a susceptible host with the blood fluke
Schistosoma mansoni results in the formation of periovular
granulomas and subsequent
fibrosis in the target organs . -
pubmed
Although the prevalence of significant
hypoglycaemia following pancreas transplantation remains unknown , it is important to conduct studies to determine the mechanisms , the natural history , predictors and treatment as well as the long - term prognosis ( graft and
patient survival rates ) of
type 1 diabetic patients who develop pancreas - allograft - associated
hypoglycaemia . -
pubmed
Finally , whether postpancreas allograft transplantation - associated
hypoglycaemia in
type 1 diabetic patients carries greater morbidity and mortality when compared to those without
hypoglycaemia deserves to be investigated . -
pubmed
[ The mineral density of the bone tissue in
patients with
rheumatic diseases of the joints ( based on x - ray densitometry data ) ] . -
pubmed
Manifestations were studied of
systemic osteoporosis in
patients with
rheumatoid arthritis ,
primary osteoarthrosis , and
ankylosing spondylarthritis . -
pubmed
A conclusion has been reached that it is necessary that the above - mentioned studies be made in order that we might choose relevant therapeutic alternatives for
patients with
rheumatic afflictions of the joints . -
pubmed
At the end of the observation period signs of
left ventricular backward failure were , however , detected in 75
rats with placebo and in 67
rats treated with
quinapril ( P=0.229 ) . -
pubmed
Clinical trials have shown
infliximab to be effective in producing and maintaining a clinical response in
patients with refractory , moderate to severe
CD . -
pubmed
Infliximab appears useful in the treatment of
CD and may improve
patients ' quality of life . -
pubmed
The aim of this study was to compare the effects of different rates of application of a commonly used physiotherapeutic spinal manipulative therapy technique on sympathetic function in normal
pain - free
volunteers . -
pubmed
Patients with
end - stage renal disease (
ESRD ) suffer from a secondary form of complex
dyslipidemia consisting of both quantitative and qualitative abnormalities in serum lipoproteins resulting from alterations in lipoprotein metabolism and composition . -
pubmed
The contribution of this complex and atherogenic form of
dyslipidemia to
cardiovascular disease in
patients with
renal disease is unclear at present . -
pubmed
Nevertheless ,
patients with
renal disease belong to a very high cardiovascular risk group and
dyslipidemia should most likely be subjected to sufficient lipid - lowering therapy in most
patients . -
pubmed
Seven healthy
volunteers with no family history of
NIDDM were studied on two occasions during a 12 - h oscillatory
glucose infusion with a periodicity of 144 min . -
pubmed
METHODS : From 1993 to 2000 , 74
patients with pathological T1N0M0
lung cancer were treated by the pulmonary artery - guided segmentectomy . -
pubmed
According to
tumor size , the 5 - year survival rate for
patients with
tumors of 20 mm or smaller ( 92.9 % , n=53 ) was higher than that for the
patients with
tumors of 21 - 30 mm ( 63.0 % , n=21 ) , but the difference did not reach statistical significance . -
pubmed
Locoregional
recurrences occurred in one of 53
patients ( 1.9 % ) with
tumors 20 mm or smaller and in seven of 21
patients ( 33.3 % ) with
tumors 21 - 30 mm , the difference being statistically significant ( P<0.01 ) . -
pubmed
CONCLUSIONS : Our intermediate results demonstrated that the new pulmonary artery - guided segmentectomy could be an alternative method for selected
patients with small
lung cancer , particularly with
tumors 20 mm or smaller in diameter . -
pubmed
Fifteen months after
lamivudine treatment was started , a breakthrough due to
lamivudine - resistant
strain M5521 occurred . -
pubmed
Recent studies define a subgroup of
patients at higher risk of
renal failure during induction chemotherapy . -
pubmed
All
children were treated for
lymphoproliferative malignancy with conventional preventive measures . -
pubmed
RESULTS : Three
children needed haemodialysis--2
boys had fully expressed
TLS with
ARF shortly after starting chemotherapy , in 1 boy the dialysis was indicated because of extreme
hyperuricemia and high
creatinine level presented before chemotherapy . -
pubmed
OBJECTIVES : To compare the degree of
osteoporosis and bone metabolism markers between elderly
women with
COPD and those with
bronchial asthma who had never received chronic systemic
corticosteroids , and to determine the factors influencing bone metabolism in these
patients . -
pubmed
PATIENTS : A total of 44 elderly female
patients with
COPD ( n = 20 ) or
bronchial asthma ( n = 24 ) who had not received chronic systemic
corticosteroids were enrolled ( mean + /- SEM age , 74.6 + /- 1.0 years ) . -
pubmed
Clean MAS observation of
13C - labeled
carbons in membrane - bound
HIV-1 and
influenza fusion peptides was made by using a rotational - echo double - resonance spectroscopy ( REDOR ) filter of directly bonded
13C-15N pairs . -
pubmed
Influence of suspended solids on acute
toxicity of
carbofuran to
Daphnia magna : I. Interactive effects . -
pubmed
[
Chronic polyarthritis in
children treated by
delta 5 pregnenolone ] . -
pubmed
[ EXPERIENCE WITH DISPENSARY SERVICES TO
PATIENTS WHO RECOVERED FROM
EPIDEMIC HEPATITIS IN INFECTIOUS DISEASE CLINICS ] . -
pubmed
[ The circulatory system in
patients with
familial hypercholesterolemic xanthomatosis ] . -
pubmed
Furthermore , no studies have compared prophylactic therapy for every
patient versus therapy only for those
patients who experience
AF after heart surgery . -
pubmed
OBJECTIVES : To report one case of
adrenal gland cyst in a
patient presenting with
lower urinary tract symptoms . -
pubmed
OBJECTIVE : To evaluate the effectiveness of
tramadol hydrochloride for the treatment of
chronic pain refractory to previous treatment in two pediatric
patients . -
pubmed
METHODS :
Tramadol hydrochloride was administered ( 50 mg / day to 150 mg / day ) to two
siblings with
Ehlers - Danlos syndrome -
Hypermobility type refractory to previous pharmacological treatments , and changes in
pain intensity and physical activity were assessed . -
pubmed
CONCLUSIONS :
Tramadol hydrochloride was a safe and effective treatment for relieving
chronic pain in two pediatric
patients suffering from the
hypermobility type of Ehlers - Danlos syndrome . -
pubmed
OBJECTIVE :
Renal and hormonal abnormalities , manifesting as
oedema or
hyponatraemia , are often seen in
patients with
COPD . -
pubmed
The aim of this study was to investigate the effect of
airflow obstruction and arterial blood gas abnormalities on
oedema formation in
COPD patients . -
pubmed
METHODOLOGY : A total of 58
COPD patients hospitalized for treatment of
COPD exacerbation were admitted to the study . -
pubmed
Of these , 38
patients had
peripheral oedema ( group 1 ) and 20
patients had no
oedema ( group 2 ) . -
pubmed
Hyponatraemia occurred in five
patients ( 13 % ) in group 1 and one
patient ( 5 % ) in group 2 . -
pubmed
CONCLUSION : Alterations in pH and PaCO2 (
respiratory acidosis and
hypercapnia ) appear to have more prominent roles than
hypoxaemia in
oedema formation in
COPD patients . -
pubmed
Circadian blood pressure profile in
patients with
Cushing ' s syndrome before and after treatment . -
pubmed
The aim of the study was to evaluate the circadian blood pressure ( BP ) profiles in
patients with two forms of
Cushing ' s syndrome , and to compare them to those in
patients with
essential hypertension . -
pubmed
The study included 100
patients with
Cushing ' s syndrome ( 80 with
pituitary adenomas and 20 with
adrenal adenomas ) and 40 with
essential hypertension . -
pubmed
The awake - sleep differences between the
patients with two forms of
Cushing ' s syndrome were similar . -
pubmed
The night - time BP decline in the
patients with
Cushing ' s disease , as well as in those with
adrenal adenomas , was significantly lower than that in the
patients with essential
hypertension . -
pubmed
In the
patients with both forms of
Cushing ' s syndrome , there was a highly significant decline in the office and ambulatory BP levels after the treatment , and the awake - sleep systolic BP difference became significantly higher . -
pubmed
The night - time diastolic BP decline was significantly higher after treatment in
patients with
adrenal adenomas and not - significantly higher in
patients with
Cushing ' s disease . -
pubmed
In the
patients with
Cushing ' s disease , the duration of
hypertension was greater , and lower percentage of normalized BP after treatment was observed in comparison with the
patients with
adrenal adenomas . -
pubmed
Between December 1998 and July 2002 , we operated on 12
patients with multiple
thoracic disc herniations . -
pubmed
PATIENTS AND METHODS : This is a retrospective study including 83
patients who underwent emergency operations for completely obstructing
colorectal cancers from 1991 to 2002 . -
pubmed
The effect of electromagnetic terahertz oscillations at frequencies of the molecular spectrum of
nitric oxide radiation and absorption ( 150.176 - 150.664 GHz ) on the properties of
blood coagulation in white laboratory
rats subjected to immobilization stress was studied . -
pubmed
Clinical outcome in
patients with
bipolar I disorder ,
obsessive compulsive disorder or both . -
pubmed
A cross - sectional survey on a cohort of
HIV - infected women seen at 27
HIV clinics was performed . -
pubmed
PURPOSE : This review aims to provide a literature survey of the association between photo - oxidation of lens proteins and lipid peroxidation with the genesis of age - related
cataract in laboratory studies using
rodent models , in epidemiological and interventional studies in
humans . -
pubmed
Dietary antioxidants are central in retarding cataractogenesis , although most evidence for this is gained from laboratory - based work on relatively unphysiologic
rodent cataract models , using antioxidant regimes that could not be sustained in clinical practice . -
pubmed
DESIGN : Twenty limbs of 18
patients with
venous leg ulcers were studied , median age 76 years . -
pubmed
Death at a discount : how the
tobacco industry thwarted
tobacco control policies in US military commissaries . -
pubmed
Repair of
oronasal fistulae using auricular cartilage grafts in five
cats . -
pubmed
OBJECTIVE : To describe repair of chronic
palatine defects in
cats , with free cartilage graft harvested from either the pinna ( scapha ) or vertical ear canal ( annular cartilage ) . -
pubmed
ANIMALS :
Cats ( n=5 ) with
chronic oronasal fistula . -
pubmed
CONCLUSIONS : Auricular cartilage provides a reliable framework for repair of
oronasal fistulae in
cats . -
pubmed
We recommend using conchal cartilage as the initial treatment approach for repair of small
oronasal fistulae in
cats . -
pubmed
Effect of a vigorous aerobic regimen on physical performance in
breast cancer patients - a randomized controlled pilot trial . -
pubmed
This randomized , controlled pilot trial was carried out to assess the feasibility and efficacy of an aerobic exercise in enhancing physical performance of
breast cancer patients after adjuvant treatments . -
pubmed
Extrahepatic abdominal hydatid disease caused by
Echinococcus granulosus : imaging findings . -
pubmed
OBJECTIVE : The classical findings in
hydatid disease caused by
Echinococcus granulosus with liver or lung involvement are well known . -
pubmed
Treating
patients with
overactive bladder syndrome with antimuscarinics : heart rate considerations . -
pubmed
The emergence and spread of the
PVYNTN strain , which is the causative agent of
potato tuber necrotic ringspot disease (
PTNRD ) , has lead to large economic losses and highlighted the need for accurate discrimination of the different
PVY strains . -
pubmed
BACKGROUND : Fast changes in
human demographics worldwide , coupled with increased mobility , and modified land uses make the threat of emerging
infectious diseases increasingly important . -
pubmed
METHODOLOGY / PRINCIPAL FINDINGS : We develop an extension of standard epidemiological models , appropriate for emerging
infectious diseases , that describes the probabilistic progression of case numbers due to the concurrent effects of ( incipient )
human transmission and multiple introductions from a reservoir . -
pubmed
We apply the methodology to case data from World Health Organization reports to place bounds on the current transmissibility of
H5N1 influenza in
humans and establish a statistical basis for monitoring its evolution in real time . -
pubmed
I will suggest that a diverse group of
vasculitic disease entities , with similar histologic patterns of
vascular inflammation , are the result of this mechanism , inherited from the social amoebae and invertebrate
echinoderms at the very base of the
deuterostome lineage . -
pubmed
STA-9090 activity was tested in a
canine mastocytoma xenograft model . -
pubmed
Lastly ,
STA-9090 inhibited
tumor growth in a
canine mastocytoma mouse xenograft model . -
pubmed
METHOD : We searched for articles in English published in peer - reviewed journals that perform cost - utility analyses to evaluate the addition of
HPV vaccine to 12 - year - old girls to existing
cervical cancer screening practices . -
pubmed
In this case report , we describe a 7 - year - old
patient with isolated
lung epithelial - myoepithelial carcinoma and the management of such a lesion . -
pubmed
SUMMARY :
Infection of the snail ,
Biomphalaria glabrata , by the free - swimming miracidial stage of the
human blood fluke ,
Schistosoma mansoni , and its subsequent development to the parasitic sporocyst stage is critical to establishment of viable
infections and continued
human transmission . -
pubmed
OBJECTIVES : To isolate and characterize
human muscle - derived cells ( MDCs ) for future management applications on
lower urinary tract symptoms , including
stress urinary incontinence and bladder reconstitution . -
pubmed
The development of muscle stem cells for transplantation or gene transfer in
patients with
muscle disorders has become more attractive and challenging recently . -
pubmed
Human MDCs might have the potential to be a novel tool for the management of
stress urinary incontinence and bladder reconstitution . -
pubmed
Earlier diagnosis , treatment of exacerbations , and the use of long - term therapies have all improved the lifespan of
patients with
cystic fibrosis (
CF ) . -
pubmed
Results showed that the two fermentatively different
strains of facultative anaerobes ,
Escherichia coli E 17 and
Klebsiella mobilis ATCC 13048 grew in balance regardless of
oxygen level ,
bile acid concentration or other components of the mixed cultures ,
Bacillus cereus or
Staphylococcus aureus . -
pubmed
Only 13.24 % of the 287 patient samples were sterile , and around 180
strains of both
E. - pubmed
Enterococcus sp . accounted for 246 isolates being the largest group of
strains ( 24.25 % of all the isolates ) . -
pubmed
48 % of
patients had a prior
myocardial infarction and 25 % had already coronary bypass surgery ( CABG ) . -
pubmed
PATIENTS AND METHODS : Four
seborrheic blepharitis patients with Malassezia spp . -
pubmed
Different aspects of the
Lewis ( x ) glycomimetic peptide were investigated by introducing it in in vitro assays measuring neurite outgrowth and in in vivo assays to determine its efficacy in regeneration of peripheral nerve and spinal cord after
injury in adult
mice . -
pubmed
For lymphadenectomy to have clinical utility in the care of
women with
stage IA2 cervical carcinoma , a sufficiently high incidence of node positivity would be required to justify the morbidity of the procedure for the whole group . -
pubmed
We assessed structural changes on brain imaging and neuropsychological outcomes in
critically ill patients who developed neurological changes during their intensive care unit ( ICU ) stay . -
pubmed
Patients with
idiopathic PAH (
IPAH ) ( n = 44 ) and normal
individuals ( n = 13 ) served as control subjects . -
pubmed
Chronic treatment with
D - chiro - inositol prevents autonomic and
somatic neuropathy in
STZ - induced
diabetic mice . -
pubmed
METHODS :
Streptozotocin - induced (
STZ )
diabetic mice were treated by oral gavage for 60 days with
DCI ( 20 mg / kg/12 h ) or saline (
NaCl 0.9 % ; 0.1 ml/10 g/12 h ; Diab ) and compared with euglycaemic groups treated with saline ( 0.1 ml/10 g/12 h ; Eugly ) . -
pubmed
It is based on the ex vivo expansion and activation of
tumor - specific T lymphocytes extracted from the
tumor and their administration back to the
patient . -
pubmed
BACKGROUND : Statins are an important part of the treatment plan for
patients with
type 2 diabetes . -
pubmed
OBJECTIVE : To estimate the influence of adherence on the optimal timing of statin initiation for
patients with
type 2 diabetes . -
pubmed
It has increasing importance for liver transplant ( OLT )
patients , in particular if when there is
decreased renal function . -
pubmed
In 10
patients , the
cholestasis associated with chronic rejection was sharply reduced after the introduction of
sirolimus . -
pubmed
CONCLUSION :
Sirolimus given alone or in combination with CNIs appears to be an effective primary immunosuppressant regimen for
OLT patients . -
pubmed
RESULTS :
Green tea intake ( & gt;=500 ml / d ) was inversely associated with
ccRCC risk , with an AOR of 0.34 ( 95 % CI 0.21 - 0.55 ) . -
pubmed
CONCLUSION :
BMI ( & gt;=25 kg / m(2 ) ) ,
hypertension , and
urolithiasis are independently associated with an increased risk , whereas
green tea intake ( & gt;=500 ml / d ) is independently associated with a decreased risk of
ccRCC . -
pubmed
With the increasing rate of
obesity and the potentially simultaneous development of
sarcopenia , bedrest presents a difficult clinical challenge to the elderly
individual . -
pubmed
Development of a home - based telehealthcare model for improving the effectiveness of the chronic care of
stroke patients . -
pubmed
This study describes the development of an information technology ( IT)-mediated home - based healthcare model designed to improve the effectiveness of caring for
stroke patients who require chronic , home care . -
pubmed
This model was evaluated at Kaohsiung Medical Hospital in Taiwan between 2005 and 2008 ; 84 newly diagnosed
stroke patients diagnosed as the chronic covalence stage were enrolled for preliminary testing of this model . -
pubmed
Evaluation of the trachea and intrathoracic airways by the acoustic reflection method in
children with
cystic fibrosis . -
pubmed
Tracheomalacia has been observed in older
patients with
cystic fibrosis (
CF ) . -
pubmed
The mean MTAv value was comparable in the
CF patients and the control subjects during SB , FI , and FE . -
pubmed
A 62 - year - old
man with a
right subclavian artery aneurysm had had a history of bird hunting using a shotgun that impacted substantially against his right clavicula and shoulder weekly for & gt;20 years . -
pubmed
The availability of suitable
animal models and the opportunity to record electrophysiologic data in
movement disorder patients undergoing neurosurgical procedures has allowed researchers to investigate
parkinsonism - related changes in neuronal firing patterns in the basal ganglia and associated areas of the thalamus and cortex . -
pubmed
Type 2 diabetes mellitus in
mice aggravates the renal impact of
hemorrhagic shock . -
pubmed
The objectives of this study were to determine whether
type 2 diabetic mice would exhibit a more severe renal impact of
hemorrhagic shock (
HS ) based on a recently described model of
acute kidney injury and to determine the impact of HS on renal responses to
hypoxia . -
pubmed
We induced HS or sham procedure in
type 2 diabetic and
obese db / db
mice . -
pubmed
Diabetic mice exhibiting mild
diabetic nephropathy express hypoxic signals at baseline . -
pubmed
The renal impact of
HS was more severe in
diabetic mice , with a worsening of tissular
hypoxia and an altered response to
hypoxia . -
pubmed
Renal impact of HS in
type 2 diabetic mice is more intense than in nondiabetic ones . -
pubmed
METHODS AND RESULTS : A total of 5953 Danish
men and
women aged 30 - 60 years without baseline
diabetes or
cardiovascular diseases were included in this prospective analysis . -
pubmed
Non - Hodgkin ' s lymphoma in a
patient on treatment with
temozolomide . -
pubmed
A 68 - year - old
man was diagnosed with
glioblastoma multiforme of the right basal ganglia in March 2010 . -
pubmed
In the present review , we discuss the phenotypic differences between
mice of the inbred C57BL/6J and DBA/2J strains that could be associated with the
strain - specific resistance to helplessness observable in DBA/2J
mice . -
pubmed
Variables significantly associated with increased cost in the multivariate analysis were complicated
pneumonia ( & gt;=2 and 1 complication ) versus non - complicated
pneumonia ( $ 4919 and $ 2822 vs. $ 1399 ) , performance of surgery versus no surgery ( $ 4849 vs. $ 1435 ) , intensive care versus no intensive care ( $ 6488 vs. $ 3862 ) and identification of non -
PCV7 serotypes versus
PCV7 serotypes ( $ 4656 vs. $ 1470 ) . -
pubmed
CONCLUSION : Invasive
pneumococcal pneumonia in children makes substantial demands on hospital health care and financial resources that could be mitigated with universal
PCV13 childhood immunization programmes and early management of complications . -
pubmed
One hundred and fifty - six
women age 18 - 65 years were enrolled at diagnosis of first
venous thromboembolism (
VTE ) . -
pubmed
The application and efficacy of combined neurofeedback therapy and imagery training in
adolescents with
Tourette syndrome . -
pubmed
We aimed to examine the effectiveness of combined neurofeedback therapy and imagery training in adolescent
patients with refractory
Tourette syndrome . -
pubmed
Patients showed significant improvement in motor
tic and
vocal tic symptoms , exemplified by a reduction in the frequency and intensity of
tics , indicating that neurofeedback , together with imagery training , has a positive therapeutic effect on adolescent
patients with medication - refractory
Tourette syndrome . -
pubmed
The overexpression of peptide receptors in many
human cancers has attracted an enormous interest in targeting molecules for the development of
tumor - specific radiopharmaceutical compounds for diagnostic imaging and therapy of
cancers . -
pubmed
Selective detection of
tumor cells while sparing normal tissue is possible and peptide - receptor ligands are the tools for obtaining the probes needed to explore specific biological and
pathological processes in both animals and
humans . -
pubmed
METHODS AND RESULTS : Consecutive
patients having undergone PVs isolation as repeat procedure for recurrent
AF after an initial CB ablation were eligible for this study . -
pubmed
At mean 20.2 + - 10.7 months follow - up , a total of 16
patients ( 55 % ) were free of
AF at without antiarrhythmic drugs ( AADs ) . -
pubmed
Adenoviral vectors carrying the enhanced green fluorescent protein ( EGFP ) transgene were used at different multiplicities of
infection ( MOI ) to infect multiple cell types , both in standard static and in perfused conditions . -
pubmed
Our results validate the mathematical models and demonstrate how the
infection processes through perfusion via microfluidic platform led to an enhancement of
adenoviral infection efficiency even at low MOIs . -
pubmed
OBJECTIVE : To explore the evidence regarding the effectiveness of dry needling to reduce
pain in
patients with
MPS of the upper quarter . -
pubmed
The findings of 3 studies that compared dry needling to sham or placebo treatment provided evidence that dry needling can immediately decrease
pain in
patients with upper - quarter MPS , with an overall effect favoring dry needling . -
pubmed
The findings of 2 studies that compared dry needling to sham or placebo treatment provided evidence that dry needling can decrease
pain after 4 weeks in
patients with upper - quarter MPS , although a wide confidence interval for the overall effect limits the impact of the effect . -
pubmed
CONCLUSION : Based on the best current available evidence ( grade A ) , we recommend dry needling , compared to sham or placebo , for decreasing
pain immediately after treatment and at 4 weeks in
patients with upper - quarter MPS . -
pubmed
A 40 - year - old
man with a medical history of
hypertension was admitted for
weight loss , generalised
weakness , joint
pains and
mottling of fingertips . -
pubmed
METHODS : From August 2011 to November 2011 , 25
patients with
ACL injuries were treated with arthroscopic reconstruction of ACL using hamstring tendon . -
pubmed
Fifteen
patients had
injuries in left knees , and 10
patients had
injuries in right knees . -
pubmed
The duration of the disease ranged from 1 to 60 d , with a mean of 9.6 d. All
patients with acute
injuries had
swelling and
pain on the knee , and anterior drawer test showed positive results in 14 cases , Lachman test showed positive results in 17 cases . -
pubmed
Among
patients with old
injuries , 5
patients had
knee joint pain , 5
patients had
unstability of knee joint , 5
patients had positive results of anterior drawer test , and 5
patients had positive results of Lachman test . -
pubmed
There were 20
patients with acute
injuries and 5
patients with old
injuries . -
pubmed
RECENT FINDINGS : Symptoms in
men with
chronic prostatitis /
CPPS appear to cluster into a group with primarily
pelvic or localized disease , and a group with more systemic symptoms . -
pubmed
Future therapy may include antibodies to mediators of
neurogenic inflammation and even treatment of
bacteria in the bowel . -
pubmed
SUMMARY : The diagnosis of
chronic prostatitis /
CPPS must include conditions traditionally outside the scope of urologic practice but important for the care of
men with chronic
pelvic pain . -
pubmed
We present two
patients , one of them with suspected biochemical
prostate cancer and one with biochemical
recurrence after radical treatment . -
pubmed
Despite intensive treatment with chemotherapy , radiotherapy and surgery , over 70 % of
patients with metastatic
Ewing ' s Sarcoma Family of
Tumors (
EFT ) will die of their disease . -
pubmed
METHODS : To examine prehospitalization symptom scenarios , semistructured interviews were conducted with 60
patients hospitalized for acute decompensated
HF . -
pubmed
Screening for
cognitive and affective dysfunction in
patients suspected of mild
cognitive impairment . -
pubmed
The goal of this study was to determine if
patients with
mild cognitive impairment (
MCI ) of the amnestic type would demonstrate impairments in these domains , as well as show expected
memory deficits . -
pubmed
METHODS : Thirty - nine French - speaking
patients with a clinical diagnosis of
MCI were compared with 39 age- and education - matched normal functioning
individuals on the French translation of the Barrow Neurological Institute Screen for Higher Cerebral Functions ( BNIS ) . -
pubmed
RESULTS :
Patients with
MCI performed significantly worse than controls on the BNIS subtests sampling memory , orientation , affect expression and perception , and accurate prediction of memory performance . -
pubmed
CONCLUSION : This sample of
MCI patients demonstrated disturbances not only in memory but also in self - awareness and affect expression and perception on the BNIS . -
pubmed
Successful Electroconvulsive Therapy in a
Clozapine - Refractory
Schizophrenia Patient with
Meningioma . -
pubmed
Thus synergistic effects on
cypermethrin toxicity of
A. - pubmed
Forty - nine
people with moderate to severe
chronic obstructive pulmonary disease completed 4 months of training and provided valid accelerometry data , and 34 also provided accelerometry data at 12 months of follow - up . -
pubmed
METHODS : A
subject with
Bietti crystalline tapetoretinal dystrophy was evaluated with ophthalmoscopy ,
fluorescein angiography , and OCT ( Stratus ) . -
pubmed
Tumor samples and clinical data were obtained from 50
patients with
craniopharyngioma who were admitted to the West China Hospital of Sichuan University ( Chengdu , China ) . -
pubmed
Measurement of the endotracheal cuff pressure was continued until the extubation of endotracheal or tracheostomy tube , or
death of the
patient . -
pubmed
The possible influencing factors were evaluated in the two groups , including
body mass index (
BMI ) , size of endotracheal tube , duration of intubation , use of sedative or analgesic , number of leaving from intensive care unit ( ICU ) , the number of turning over the
patients , and
aspiration of sputum . -
pubmed
CONCLUSIONS : Abnormal endotracheal cuff pressure is common in
critically ill patients with intratracheal intubation . -
pubmed
A 7 - year - old
boy presented with
fever and
ataxia 20 days after oral
polio vaccination . -
pubmed
PATIENTS AND METHODS : Forty - four
patients ( 34 male and mean age of 54.9 + - 10.9 years ) with acute
STEMI were included . -
pubmed
CONCLUSIONS : TPE measured from surface ECG recordings is significantly reduced in
STEMI patients with successful reperfusion after primary PCI , as determined by IC - ECG recordings . -
pubmed
We present the age - related schedules for immunizations against yellow and
typhoid fevers ,
hepatitis A and B , tick - borne and Japanese
encephalitis , and
rabies . -
pubmed
In experiments , isolate ZJ01 caused
death in 100 % of
pigs that were either 14 or 80 days old . -
pubmed
The impact of oral anticoagulation on time to surgery in
patients hospitalized with
hip fracture . -
pubmed
A significant number of
hip fracture patients have concomitant
cardiovascular disease requiring anticoagulation . -
pubmed
MATERIALS AND METHODS : This is a case control study comparing TTS in consecutively admitted
hip fracture patients receiving either a DOAC or VKA with age- and gender - matched controls between January 1 , 2010 and March 24 , 2014 . -
pubmed
CONCLUSIONS :
Patients on anticoagulation prior to admission for
hip fracture experienced longer delays in surgery when compared to patients not receiving anticoagulation . -
pubmed
Patients were without significant
renal or hepatic failure or
shock at entry . -
pubmed
Here , we investigated whether systemic perfusion pressure , a key driver of
tumor blood flow , could influence the intratumoral extravasation of systemically administered oncolytic
vesicular stomatitis virus ( VSV ) in
myeloma tumor - bearing
mice . -
pubmed
OBJECTIVES : The effect of
agmatine on bladder contractility and the
diabetes - induced alteration of this action were studied in the
rat . -
pubmed
METHODS : Bladder strips were isolated from 9 - week - old
streptozotocin (
STZ)-
diabetic rats and control
Wistar rats . -
pubmed
Relaxation was significantly increased in
STZ -
diabetic rats . -
pubmed
Two of 181 ( 1.1 % )
patients died , 5 of 181 ( 2.8 % ) lost their grafts , 12 of 181 ( 6.6 % ) had an episode of acute rejection , 13 of 181 ( 7.2 % ) had & gt;=1 serious event and
infection , and 85 of 181 ( 49.9 % ) had & gt;=1 nonserious adverse event or
infection . -
pubmed
Suspected
laryngeal granuloma secondary to chronic endotracheal intubation in a
dog . -
pubmed
Prevalence characteristics of high - risk
human papillomaviruses in women living in Shanghai with cervical
precancerous lesions and
cancer . -
pubmed
A complete understanding of the natural history of
infection with high - risk
human papillomaviruses (
HPVs ) in
cervical cancer requires data from regional and ethnic studies . -
pubmed
The prevalence of high - risk
HPVs was evaluated retrospectively in 2040 patients with
cervicitis , 239 with
cervical intraepithelial neoplasia grade 1 ( CIN1 ) , 242 with CIN2/3 , and 42 patients with
invasive squamous cell carcinoma (
SCC ) based on data from patients who visited our hospital between May 2013 and May 2015 . -
pubmed
HPV16 and
HPV58 positivity in
cervicitis , CIN1 , CIN2/3 , and
SCC patients were 20.9 % and 16.4 % , 19.0 % and 20.1 % , 44.1 % and 23.5 % , and 60.0 % and 31.4 % , respectively . -
pubmed
Compared to
cervicitis , the odds ratios ( ORs ) for CIN2/3 in HPV16- and
HPV58 - positive patients were 2.99 ( 95 % confidence interval [ CI ] : 1.32 - 4.33 ) and 1.56 ( 1.11 - 3.21 ) , respectively ; for
SCC , the corresponding values were 5.68 ( 2.31 - 7.893 ) and 2.33 ( 1.41 - 3.87 ) . -
pubmed
Further identifying of carcinogenic HPVs and a fully aware of regional differences in
HPV genotype distribution are tasks of top priority for
cervical cancer control and prevention . -
pubmed
The present study was carried out to investigate the effect and mechanisms of aloe -
emodin ( AE)-mediated photodynamic therapy ( AE - PDT ) on the
human osteosarcoma cell line
MG-63 . -
pubmed
After treatment with AE - PDT , the
human osteosarcoma cell line
MG-63 was tested for levels of viability , autophagy , reactive
oxygen species ( ROS ) and apoptosis and changes in cell morphology with the Cell Counting Kit-8 (
CCK-8 ) ,
monodansylcadaverine (
MDC ) and Hoechst staining and transmission electron microscopy . -
pubmed
METHODS : A total of 55
adults with comitant
horizontal strabismus participated in a prospective observational clinical series . -
pubmed
Thirty - one
patients with
esodeviations received
BPX injections in a lateral rectus muscle , some with BTXA in the medial rectus ; 24
patients with
exodeviations received
BPX in a medial rectus muscle , some with BTXA in the lateral rectus muscle . -
pubmed
[ Contact lens - associated
Paecilomyces lilacinus keratitis ] . -
pubmed
We present the case of a 23 - year - old otherwise healthy female patient with contact lens - associated
Paecilomyces lilacinus keratitis . -
pubmed
METHODS : BCP
mouse model was established by
osteosarcoma cell inoculation . -
pubmed
A total of 35
cows were diagnosed and treated for
periparturient paresis and , therefore , excluded from the study . -
pubmed
In this study , we report a
woman with a history of recurrent pregnancy losses (
RPL ) and
infertility who had low levels of memory B cells . -
pubmed
The subjects were
children and
adolescents with
hypothyroidism due to
dyshormonogenetic goiter . -
pubmed
Patients with
Parkinson ' s disease (
PD ) have higher - order
sensory dysfunctions including prolonged temporal discrimination threshold ( TDT ) . -
pubmed
METHODS : This study includes 33
PD patients and 24 healthy controls . -
pubmed
RESULTS : Compared to healthy controls , TDT was prolonged in the
PD patients . -
pubmed
Therefore , with the current public health concern on antibiotic resistance globally , in this review , we underscore the need to screen probiotic
strains that are used in both livestock and
human applications to assure their safety and mitigate their potential in significantly contributing to the spread of antibiotic resistance genes in our natural environments . -
pubmed
Methods : Between January 2000 and December 2014 , 60
patients were treated with endovascular aortic stent graft for
injury of the aortic isthmus . -
pubmed
One
patient had a
type 1 endoleak without any reintervention . -
pubmed
Nonetheless ,
FAP deficient mice showed similar pathologic kinetics to wildtype controls , and were capable of supporting normal anti -
influenza T and B cell responses . -
pubmed
OBJECTIVES : The primary objective of this prospective study was to determine the prevalence of
paroxysmal atrial fibrillation (
PAF ) in
patients aged 40 and above in a population who underwent continuous 24 - hour electrocardiographic monitoring . -
pubmed
At least one episode of
PAF was detected in 123
patients , a prevalence of 2.5 % ( 95 % CI : 2.1 - 3.0 ) . -
pubmed
Transarterial chemoembolization combined with recombinant
human adenovirus type 5 H101 prolongs overall survival of
patients with intermediate to advanced
hepatocellular carcinoma : a prognostic nomogram study . -
pubmed
BACKGROUND :
Patients with intermediate to advanced
hepatocellular carcinoma (
HCC ) are most commonly treated with transarterial chemoembolization ( TACE ) . -
pubmed
In the present study , we aimed to determine the survival benefit of TACE with or without H101 for
patients with intermediate to advanced
HCC and to develop an effective nomogram for predicting individual survival outcomes of these
patients . -
pubmed
METHODS : We retrospectively collected data from 590
patients with intermediate to advanced
HCC who were treated at Sun Yat - sen University Cancer Center between January 2007 and July 2015 . -
pubmed
CONCLUSIONS : TACE plus H101 extends the survival of
patients with intermediate to advanced
HCC . -
pubmed
Our proposed nomogram provides individual survival prediction and stratification for
patients with intermediate to advanced
HCC who receive TACE with or without H101 . -
pubmed
The poor predictive quality of currently used
animal models in preclinical research is an important cause of the high attrition of promising drug candidates for
human autoimmune disease in clinical trials . -
pubmed
Examples from own work in a
primate multiple sclerosis (
MS ) model illustrate that important lessons can be learned from a critical reassessment of failed drugs in the
animal model , which can help improve the
animal model and better understand the targeted disease . -
pubmed
BACKGROUND : Little is known about physical activity in daily life among
patients with
sarcoidosis . -
pubmed
METHODS : In
patients with
sarcoidosis , we measured physical activity ( steps per day ) by accelerometry ( SenseWear Armband ) for 1 week . -
pubmed
RESULTS : We investigated 57
patients with
sarcoidosis ( mean age 50 years , 56 % male , mean DLCO 73 % predicted , mean FVC 91 % predicted , mean 6MWD 525 m , mean steps per day 7,490 ) , of whom n = 14 ( 25 % ) had severe
fatigue . -
pubmed
MATERIALS AND METHODS : From January 1993 to March 2017 , 130
patients with primary
tumors in the APG region who underwent surgical treatment were enrolled . -
pubmed
RESULTS : Among the 130
patients , 53.8 % of lesions were benign ( n = 70 ) , 23.8 % were
malignant ( n = 31 ) , 14.6 % were
vascular malformations ( n = 19 ) , 6.15 % were
sialadenitis ( n = 8) , and 1.65 % were
cysts ( n = 2 ) . -
pubmed
OBJECTIVE : To assess the clinical effectiveness of a wearable patient sensor to improve care delivery and
patient outcomes by increasing the total time with turning compliance and preventing
pressure injuries in acutely ill
patients . -
pubmed
Additional clinical trials leveraging technologies like wearable sensors are needed to establish the appropriate frequency and dosing of individualized turning protocols to prevent
pressure injuries in at - risk hospitalized
patients . -
pubmed
The proportion of synchronous
metastases was highest for
women with lymph node ( 35 % ) , postmastectomy chest wall ( 30 % ) , and in - breast ( 15 % ) recurrence ; 54 % received systemic staging imaging within 30 days of a locoregional
recurrence . -
pubmed
Conclusion These findings support current recommendations for systemic imaging in the setting of locoregional
recurrence , particularly for
patients with lymph node or chest wall
recurrences . -
pubmed
Because most
patients with isolated locoregional
recurrence will be recommended locoregional treatment , early identification of distant
metastases through routine systemic imaging may spare them treatments unlikely to extend their survival . -
pubmed
This paper first investigated the anti -
inflammation effect of
C. - pubmed
Moreover , we first evaluated the anti - RA effects of CRME using collagen - induced
arthritis (
CIA ) in DBA/1J
mice , and the incidence , clinical score , and joint histopathology were evaluated . -
pubmed
The results showed that , compared with the model group , CRME significantly improved symptoms of the
arthritis index ,
limb swelling , and histological findings by decreasing synovial membrane damage , the extent of inflammatory cell infiltration , and the expansion of capillaries in
CIA mice . -
pubmed
Randomized controlled studies that assessed the effects of dual - task training in
stroke patients were included for the review ( last search in December 2017 ) . -
pubmed
Two weeks after the onset of
FS , leukemic cells appeared on a peripheral blood smear , and the
patient was diagnosed with
precursor B - cell ALL presenting as
nephromegaly and
FS . -
pubmed
Healthcare use , costs and quality of life in
patients with
end - stage kidney disease receiving conservative management : results from a multi - centre observational study ( PACKS ) . -
pubmed
Proteomic and miRNA analyses , combined with robust bioinformatics , identified circulating biomarkers applicable to diagnose
GD , predict GO disease status and optimize
patient management . -
pubmed
SUMMARY : Noninvasive imaging allows a comprehensive assessment of
patients with suspected
pulmonary hypertension . -
pubmed
Antitubercular treatment for 6 months was completed in all the
patients with active
peritoneal disease . -
pubmed
However , controversy remains as to whether
fish oil - enriched enteral nutrition can improve clinical outcomes in adult
critically ill patients in intensive care units ( ICUs ) . -
pubmed
The aim of this study was to provide an up - to - date systematic review and meta - analysis of all randomized controlled trials of
fish oil - containing enteral nutrition addressing relevant clinical outcomes in
critically ill patients . -
pubmed
Furthermore , subgroup analysis revealed a significant reduction in 28 - d mortality , ICU LOS , and ventilation duration in
patients with
acute respiratory distress syndrome but not in other subgroups . -
pubmed
Further research should focus on the relation between the individual
critically ill patients ' immune response , the administration of
fish oil , and clinical outcomes . -
pubmed
These findings suggested that neural network abnormalities between the thalamus and the frontal lobe can be related to
social dysfunction in
patients with
schizophrenia . -
pubmed
Methods : The
rat model of
depression was established by chronic unpredictable mild stress ( CUMS ) method for 6 weeks . -
pubmed
The
sucrose preference test and the forced swimming test were performed to assess the
rats '
depression behavior . -
pubmed
Conclusions :
Energy deficiency and damaged mitochondrial ultrastructure were found in hippocampus and gastrocnemius muscle of
depressed rats established by CUMS . -
pubmed
Disrupted Plasma Membrane Protein Homeostasis in a
Xenopus Laevis Model of
Retinitis Pigmentosa . -
pubmed
Patients with a unilaterally swollen optic nerve and normal visual function most likely have
optic nerve head drusen . -
pubmed
Patients with
abnormal visual function most likely have demyelinating
optic neuritis or non - arteritic
anterior ischaemic optic neuropathy . -
pubmed
Patients with bilaterally swollen optic nerve heads and normal visual function most likely have
papilloedema , and require neuroimaging followed by lumbar puncture . -
pubmed
The cumulative proportion of
relapse - free
patients in time was analyzed by Kaplan - Meier curves . -
pubmed
Thermal ablation versus cryotherapy or loop excision to treat
women positive for
cervical precancer on visual inspection with
acetic acid test : pilot phase of a randomised controlled trial . -
pubmed
BACKGROUND : Cryotherapy is standard practice for treating
patients with
cervical precancer in see - and - treat programmes in low - income and middle - income countries ( LMICs ) . -
pubmed
Coxiella burnetii , the etiologic agent of
Q fever , replicates in an intracellular phagolysosome with pH between 4 and 5 . -
pubmed
It has been reported that platelet aggregability is enhanced in
patients with
OSAS . -
pubmed
The objective of this study was to evaluate a contemporary series of
patients with
STEMI and OHCA to characterize treatment approaches and predictors of neurologic outcome . -
pubmed
At hospital presentation , 76 % of
patients were intubated , 37 % were in
cardiogenic shock , and 33 % were receiving vasopressors . -
pubmed
A single immunotherapy agent , Pembrolizumab , is the only currently approved treatment option in subset of
patients with unresectable locally advanced , recurrent , or metastatic esophageal , gastroesophageal , or
gastric cancers after failure or intolerance of initial systemic treatments . -
pubmed
Obesity is one of the main causes of
human cardiovascular and
cerebrovascular diseases . -
pubmed
Baicalin , a bioactive
flavonoid isolated from the herbal medicine
Scutellaria baicalensis Georgi , is reported to ameliorate
obesity and
hyperlipidemia . -
pubmed
Factors Associated with Poor Outcomes in
Patients with Mild or Moderate
Acute Subdural Hematomas . -
pubmed
The 66 moderate
ASDH patients exhibited significantly higher frequencies of surgery and mortality ( 24.2 % and 13.6 % , respectively ) than the 200 mild
ASDH patients ( 8.0 % and 4.5 % , respectively ) . -
pubmed
The factors associated with poor outcomes were age ( odds ratio [ OR ] : 1.06 ) and the ISS ( OR : 1.24 ) in the mild
ASDH patients , and older age ( OR : 1.09 ) and the higher ISS ( OR : 1.15 ) in the moderate group , too . -
pubmed
Since the elimination of dog and terrestrial wild animal
rabies , bat exposures remain the only source of autochthonous lyssavirus transmission to
humans in Western Europe . -
pubmed
European bats have already been found infected with several lyssaviruses , and
human - bat interactions represent a risk of viral transmission and fatal
encephalitis for
humans . -
pubmed
Effect of
diallyl disulfide and
garlic oil on different
human astrocytoma cell lines . -
pubmed
Despite significant efforts to optimize treatment options for
patients with high - grade
glioma , the prognosis of the overwhelming majority of
patients remain poor . -
pubmed
The aim of the present study was to investigate the potential anti -
glioma properties of DAD and
garlic oil on proliferation and induction of apoptosis in four different types of
glioma cell lines representative of different grades of the disease . -
pubmed
The results showed that
garlic oil exhibits favorable anti -
cancer potential towards
gliomas of various degrees of differentiation . -
pubmed
This report describes the cases of two
patients with a maxillary lateral incisor with
palatogingival groove and extensive
endodontic - periodontal lesions . -
pubmed
Case Presentation : We report a case of 66 - year - old
man with forgotten ureteral stent for 10 years , which caused
panureteral damage . -
pubmed
At embryonic day ( E ) 18 ( term ~E22 ) ,
placental insufficiency was induced in pregnant
Wistar rats via bilateral uterine vessel ligation to generate
IUGR offspring ( n = 10 ) ; control offspring ( n = 11 ) were generated via sham surgery . -
pubmed
In IUGR versus control
rats there was no difference in object preference in the NOL or NOR , the similar and dissimilar condition of the SLR task , or in locomotion and
anxiety - like behavior in the open field . -
pubmed
Enzyme studies in
human breast tumours . -
pubmed
To test the efficacy and
toxicity of colloidal
bismuth subcitrate (
CBS ) in a double - blind trial , forty - six consecutive
outpatients with active
duodenal ulceration were randomly allocated either to treatment with
CBS or to a placebo for a period of four weeks . -
pubmed
The symptomatic assessment of the
patients receiving
CBS or placebo showed that the reduction in
pain was highly significant in both groups , but there was statistically significant difference in the degree of reduction of
duodenal ulcer size in favour of the colloidal
bismuth subcitrate - treated group ( p less than 0.025 ) . -
pubmed
CALLA reacts with leukemic cells of 110 of 134
patients ( 82 % ) with
non - T - cell ALL ; 1 of 71 ( 1 % )
patients with
acute myelogenous leukemia (
AML ) ; 2 of 7
patients ( 29 % ) with
chronic myelogenous leukemia in
blast crisis ; 7 of 92
patients ( 8 % ) with other
hematologic malignancies ; and with the
leukemic cell lines Laz 221 and
NALM-1 . -
pubmed
It does not react with the normal hematopoietic cells ,
B - or T - cell lines , or cells from 26
patients with
T - cell ALL that were tested . -
pubmed
A study of 46
patients has shown that
Clonazepam is an effective drug in preventing attacks of
pain in essential
trigeminal and glossopharyngeal neuralgia and in
Sluder ' s syndrome . -
pubmed
A
patient is described in whom electrocardiographic changes simulating acute nontransmural
myocardial infarction occurred in association with
head trauma . -
pubmed
Polymorphonuclear leukocytes from burned
patients exhibit suppressed chemotaxis possibly related to the susceptibility of such
patients to
opportunistic infection . -
pubmed
The chemotactic impairment found in leukocytes from burned
patients , however , while related to
burn size and predictive of prognosis , did not vary with the agent used for the topical therapy . -
pubmed
Twenty
patients with symptomatic
vascular rings were evaluated preoperatively with echocardiography at this institution . -
pubmed
Most ( 17/20 ) presented with respiratory symptoms in the first year of life , although in 3
patients dysphagia was the primary complaint ( at birth , 4 months , 9 years ) . -
pubmed
Barium esophagogram remains the best screening test for
children in whom a
vascular ring is suspected . -
pubmed
[ Kinetics of vaccination antibodies against
tetanus toxoid ,
diphtheria toxoid ,
measles virus ,
poliomyelitis virus and
pneumococcus after allogenic and autologous bone marrow transplantation and booster vaccination . -
pubmed
In the second part of the paper we report on the results of the
diphtheria antitoxin valuation of 8
children after allogeneic bone marrow transplantation ( BMT ) with and without
graft versus host disease (
GvHD ) as well as on the kinetics of the
diphtheria antitoxin of 5
children after allogeneic BMT with and without
GvHD and of 5
children after autologous transplantation . -
pubmed
A genetic
animal model of
anxiety . -
pubmed
Nervous pointer
dogs have been suggested as an
animal model for pathological
anxiety . -
pubmed
BACKGROUND : Clinical and morphological studies clearly indicate that most
human coronary artery stenoses are capable of vasomotion . -
pubmed
Borrelia burgdorferi : another cause of
foodborne illness ? -
pubmed
Borrelia burgdorferi was identified as the etiological agent of
Lyme disease in 1982 . -
pubmed
In
humans , the symptoms of
Lyme disease , which manifest themselves days to years after the onset of
infection , may involve the skin , cardiac , nervous and/or muscular systems , and so misdiagnosis can occur . -
pubmed
Multiple learning tasks in
patients with
ideomotor apraxia . -
pubmed
The Authors studied a group of
patients with ideomotor
apraxia (
LBD+ ) to verify if these
patients had some difficulties in multiple learning tasks in respect to non - apraxic
patients and normal control subjects . -
pubmed
On the other hand , this could be tied to an aspecific more diffuse deterioration of attention if we consider that our apraxic
patients had a greater
cerebral lesion than non - apraxic
patients . -
pubmed
Inhibitory effects of
beta - carotene on
preneoplastic lesions induced in
Wistar rats by the resistant hepatocyte model . -
pubmed
The inhibitory effects of
beta - carotene ( BC ) on
preneoplastic lesions induced in male
Wistar rats by the resistant hepatocyte model was investigated . -
pubmed
Preliminary characterization of a persistent
infection of
HeLa cells with
human rhinovirus type 2 . -
pubmed
A 50 - year - old
woman had
seronegative polyarthritis for three years , followed by
vascular obstruction with classic
Takayasu ' s arteritis . -
pubmed
Although persistent
infection with hepatitis B virus and
woodchuck hepatitis virus has been associated with development of
hepatocellular carcinoma in the host , little has been known of such an association with
ground squirrel hepatitis virus (
GSHV ) , which is closely related to the
woodchuck virus . -
pubmed
Colonies of
GSHV - infected and -uninfected
Beechey ground squirrels were observed for
tumors for a period of 5 years . -
pubmed
Integrated
GSHV DNA was found in the
hepatocellular carcinoma tissue of the one carrier animal examined , paralleling the frequent findings of integrated
hepatitis B and woodchuck
hepatitis viral DNA in
human and woodchuck
hepatocellular carcinoma . -
pubmed
Although the incidence of
liver carcinoma reported here in carrier ground squirrels is neither as great as that in carrier woodchucks nor statistically different from the incidence in noncarrier squirrels , the data presented suggest that persistent
infection with
GSHV may also be associated with
hepatocellular carcinoma . -
pubmed
Bronchial hyperreactivity was studied in 79
patients who gave a history of
allergic symptoms . -
pubmed
The influence exerted by the specific immunotherapy ( SIT ) of delayed
hypersensitivity (
DH ) to staphylococci and subsequent sensitization with
tarragon pollen on the level of immunocompetent cells in the blood and lymphoid organs of
guinea pigs was studied . -
pubmed
DNA 's from
human hepatoma and
gastric cancer mitochondria . -
pubmed
[
Simian malaria in the State of Acre , Brazil : the finding of
titi monkeys ,
Callicebus moloch cupreus , infected with
Plasmodium brazilianum ] . -
pubmed
The influencing of
post - traumatic haemorrhage by
ellagic acid in
rats whole - body irradiated with 600 R. -
pubmed
Major
coronary thrombi formation in the unanesthetized
animal . -
pubmed
[ Bone iopsy in
cattle - possibilities of chemical and histological examination to diagnose cases of
osteopathy due to mineral deficit ] . -
pubmed
In a double - blind , crossover study
gamma - vinyl GABA , 2 g / day , and placebo were administered orally for 2 weeks each to six
patients with
Huntington ' s disease . -
pubmed
Ultrasonic examination of the parathyroid glands has been used in 50 consecutive
patients with surgically verified
hyperparathyroidism . -
pubmed
In 16
patients with primary or secondary ( uraemic )
hyperplasia , 11 out of 48
hyperplastic glands in the neck were identified by ultrasound . -
pubmed
A parathyroid
adenoma was revealed in all ( 3 )
patients with
hypercalcaemic crisis . -
pubmed
Enlarged parathyroid glands were correctly located in all ( 5 )
patients with
adenomas and previous explorations of the neck , whereas two out of three glands were visualized by ultrasound prior to secondary explorations in 3
patients with
hyperplasia associated with the
multiple endocrine neoplasia syndrome type 1 . -
pubmed
A nodular
thyroid goitre was present in almost half of the
patients with a negative ultrasonic examination of the parathyroid glands . -
pubmed
We evaluated anion gap in 28
children - 18
boys and 10
girls with minimal change
nephrotic syndrome during 55 separate episodes of exacerbations . -
pubmed
Intracranial pressure changes in
patients with
head trauma during haemodialysis . -
pubmed
Intracranial hypertension and
acute renal failure are frequent complications in polytraumatized
patients with
head trauma . -
pubmed
Epidermoid carcinomas were induced in
hamster buccal pouches with use of 7.12
dimethylbenz [ a ] anthracene (
DMBA ) . -
pubmed
In five
animals that served as
tumor controls ( Group 1 ) , right buccal pouches were painted with
DMBA ( 0.5 % solution in mineral oil ) thrice weekly for 14 weeks . -
pubmed
Histopathologically , there were also fewer sites of
dysplasia ,
carcinoma in situ , and early invasive
epidermoid carcinoma than in the
tumor control
animals . -
pubmed
We studied 38 normal controls and 12
patients with
peroxisomal diseases and found complete discrimination between the two groups . -
pubmed
The effect of alimentary pectin obtained from different raw materials (
apple ,
tomato ,
cotton - wool ) on the causative agents of infectious
diarrheal diseases , belonging to the genera Shigella ,
Salmonella ,
Klebsiella ,
Enterobacter ,
Proteus and
Citrobacter , was studied under experimental conditions and in clinical observations . -
pubmed
Contact sensitivity to
Tinuvin P in
mice . -
pubmed
Two methods that gave minimum variation between the readings are presented here with interobserver and intraobserver reliability on 17
girls with adolescent
idiopathic scoliosis . -
pubmed
Phase I dose - escalation trial of
iodine 131 - labeled monoclonal antibody OKB7 in
patients with
non - Hodgkin ' s lymphoma . -
pubmed
Specific
tumor visualization was noted in eight of 18
patients . -
pubmed
Hematologic
toxicity was observed in six of 18
patients , but was severe in only two
patients . -
pubmed
131I - OKB7 was safely administered to a
patient in leukemic phase of
NHL with prompt subsequent loss of approximately 1 kg of
tumor cells from the peripheral blood without associated
tumor lysis syndrome . -
pubmed
Antidepressant response to
sleep deprivation as a function of time into
depressive episode in rapidly cycling
bipolar patients . -
pubmed
Three
patients with treatment - resistant rapidly cycling
bipolar disorder were studied with multiple
sleep deprivations ( SD ) during several
depressive episodes to assess the effect of phase or duration of a
depressive episode on SD response . -
pubmed
In 2
subjects , the duration of antidepressant response to
SD increased linearly as time into episode increased . -
pubmed
These results suggest that the neurobiological substrates underlying
depression may change over the course of an episode , resulting in an increased responsivity to
sleep deprivation later compared with earlier in the course of an episode in rapidly cycling
patients . -
pubmed
The generalizability of these findings to
unipolar patients remains to be explored . -
pubmed
PURPOSE : The outcome of radical external beam radiation therapy for 26 consecutive
patients with invasive
carcinoma of the penis treated between 1970 and 1985 was assessed to test the efficacy , and side effects of such treatment . -
pubmed
METHODS AND MATERIAL : A retrospective review of 26
patients with invasive
carcinoma of the penis and 11
patients with
carcinoma in - situ of the penis , treated at the Princess Margaret Hospital between 1970 and 1985 , was performed . -
pubmed
RESULTS : The 5 - year overall actuarial survival for
patients with invasive
cancers was 62 % ( + /- 10 ) and the cause - specific survival was 69 % ( + /- 9 ) . -
pubmed
All
patients with
carcinoma in - situ achieved a complete response and , with follow - up ranging from 1 to 14 years , none recurred . -
pubmed
CONCLUSION : We conclude that radiation therapy with surgery reserved for the management of local
recurrence is an effective first line treatment for
patients with
carcinoma of the penis . -
pubmed
We have investigated the effect of mild
hyperthermia ( 42 degrees C ) on the
cytotoxic activity of a 1 h
melphalan exposure in
human melanoma cell lines . -
pubmed
Weaver
mice have a severe
hypoplasia of the cerebellum with an almost complete loss of the midline granule cells . -
pubmed
Helicobacter pylori and
congestive gastropathy . -
pubmed
This study evaluates the prevalence and significance of
Helicobacter pylori (
H . - pubmed
118
patients were selected , i. e. 90
patients with
portal hypertension ( 66 males , 24 females , mean age 49.1 + /- 2.1 years ) and 28 noncirrhotic patients with
nonulcerative dyspepsia as a control group ( twelve males , 16 females , mean age 47.6 + /- 2.8 years ) . -
pubmed
We found also that the presence and severity of
congestive gastropathy is independent of the
H. - pubmed
SUBJECTS : Three hundred
patients undergoing abdominal , thoracic , or vascular surgical procedures who either had documented
coronary artery disease or were at high risk for
coronary disease . -
pubmed
CONCLUSION : In
patients with cardiac risk factors who are undergoing noncardiac surgery , the perioperative maintenance of normothermia is associated with a reduced incidence of morbid cardiac events and
ventricular tachycardia . -
pubmed
Resting state patterns of regional
glucose metabolism in
idiopathic depressed patients , changes in metabolism with antidepressant treatment , and blood flow changes with induced sadness in healthy subjects were used to test and refine this hypothesis . -
pubmed
HIV - related
NP impairment was generally mild , especially in the medically asymptomatic stage of
infection , and most often affected attention , speed of information processing , and learning efficiency ; this pattern is consistent with earliest involvement of subcortical or frontostriatal brain systems . -
pubmed
METHODS : Twenty - one healthy
subjects , 58
patients with
acute pancreatitis , and 20
patients with
nonpancreatic acute abdomen were studied . -
pubmed
Characterization of the
mitochondrial DNA abnormalities in the skeletal muscle of
patients with
inclusion body myositis . -
pubmed
Twenty - two
HIV+
patients with
encephalitis were studied . -
pubmed
Of these , 7 had
meningoencephalitis due to
Toxoplasma gondii (
MT ) and 15 due to
Trypanosoma cruzi (
MC ) . -
pubmed
We found that focal necrotizing
encephalitis due to Toxoplasma involved the cerebral cortex and the basal ganglia , whereas lesions due to
Trypanosoma cruzi were centered in the white matter , sometimes extending into the cortex . -
pubmed
A study has been carried out on the action of cytoskeleton and metabolic inhibitors on intracellular multiplication in
HeLa cells of a virulent
strain of
Legionella pneumophila serogroup 6 . -
pubmed
We describe a 9 - year - old white
boy with
systemic juvenile rheumatoid arthritis (
JRA ) who developed
pancytopenia and
hypersplenism at the age of 13 years . -
pubmed
In 67 borderline psychiatric
patients suffering from schizotypal / slowly developing
schizophrenic disorders and 18
patients suffering from
cyclothymia , the factor structure of the period ( interval - amplitude ) parameters of the EEG proved to be similar to that obtained in normal subjects during mental activity and reported in part I ( Lazarev , Int . -
pubmed
This report provides the first evidence for the presence of vascular apoptosis in
myocardial infarction induced in
rats by occluding the coronary artery for 7 weeks . -
pubmed
Squamous cell carcinoma , not
basal cell carcinoma , is the most common
cancer in
humans . -
pubmed
HUC were isolated from the ureters or renal pelves of two nephrectomized
adults and of two
children with
ureteropelvic junction stenosis and cultured under serum - free conditions . -
pubmed
BACKGROUND : While small improvements in outcome have occurred for
patients with locally advanced
non - small cell lung cancer (
NSCLC ) , 5 - year survival results remain low , ranging from 5 % to 20 % . -
pubmed
METHODS : Trials investigating innovative treatment strategies for
patients with locally advanced and/or unresectable
NSCLC are reviewed , including altered radiation fractionation schema , conformal 3 - dimensional radiotherapy , and combined chemoradiotherapy regimens . -
pubmed
CONCLUSIONS : Ongoing investigations are warranted to combat both local - regional and systemic failures for
patients with locally advanced
NSCLC . -
pubmed
Salviae Miltiorrhizae Radix has exhibited a beneficial effect in the improvement of
renal failure . -
pubmed
The prevalence of different
African horsesickness virus serotypes in the Onderstepoort area near Pretoria , during an outbreak of
African horsesickness in South Africa in 1995/1996 . -
pubmed
OBJECTIVE : To assess the efficacy of
acarbose monotherapy during 12 - weeks treatment on the fasting glycemic level , lipid and lipoproteins profiles , in
patients with
type 2 diabetes mellitus . -
pubmed
METHODS : Forty - four
patients ( 36
men and 8
women , mean age 55.09 + /- 1.72 years ) were included of whom 25 ( 56.81 % )
patients were previously treated with diet alone , 11(25 % ) with diet and
glibenclamide , 5(11.36 % ) with diet and
gliclazide , and 3(6.81 % ) with diet and
chlorpropamide , more than at least 3 months known duration of diagnosed
type 2 diabetes ,
body mass index (
BMI ) 23.69 + /- 0.49 kg / m2 , were insufficiently controlled on diet alone , or diet plus
sulfonylureas , were studied . -
pubmed
Almost , all adverse experiences , as reported by
patients on
acarbose , were related to the digestive system and included
diarrhea ,
flatulence ,
bloating and
nausea . -
pubmed
Parametric control of fingertip forces during precision grip lifts in
children with
DCD (
developmental coordination disorder ) and DAMP ( deficits in attention motor control and perception ) . -
pubmed
Twenty
boys with
developmental coordination disorder (
DCD ) , 11 of whom had associated
attention deficit disorder (
ADD ) , were compared with an age - matched control group of 12
boys to examine mechanisms that adapt the grip force at the digit - object interface in a precision grip task . -
pubmed
In a clinical series , amniotic membrane patches of the ocular surface were performed in 20 eyes of 20
patients with persistent
corneal epithelial defects , or as a prophylactic measure after corneal limbal transplantation . -
pubmed
The effects of muscle activation on postural stability in
diabetes mellitus patients with cutaneous sensory deficit in the foot . -
pubmed
Activity of the lower leg muscles in response to an unexpected disturbance to upright standing was studied in
diabetic patients and non - diabetic matched controls . -
pubmed
The
diabetic individuals were classified into two groups :
diabetic patients with normal cutaneous sensitivity in the foot ( n=27 ) and
patients with cutaneous
sensory deficit ( n=23 ) . -
pubmed
The results suggest that the inability to generate a neuromuscular response with consistent temporal patterning is a contributing factor to greater postural sway observed in
diabetic patients with cutaneous sensory deficit in the foot . -
pubmed
The impact of this problem in the routine treatment of
patients with
human immunodeficiency virus infection is poorly defined . -
pubmed
OBJECTIVES : Our aim was to determine what clinical features are associated with
hepatotoxicity in
human immunodeficiency virus - infected patients receiving antiretroviral therapy . -
pubmed
METHODS : Consecutive
patients in a primary care - based
human immunodeficiency virus clinic were evaluated for
hepatotoxicity . -
pubmed
In this report , we describe
patients with
hypothyroidism who were receiving therapy for multi - drug - resistant
tuberculosis ,
tuberculosis namely , resistant to at least
isoniazid (
INH ) and
rifampicin (
RFP ) , with a regimen that contained
PAS . -
pubmed
CONCLUSIONS : These data indicate that aging attenuates the vestibulosympathetic reflex in
humans and may contribute to the increased prevalence of
orthostatic hypotension with age . -
pubmed
Heparin - induced
platelet reactivity was studied in a subgroup of 86
patients . -
pubmed
Antibodies were detected in 3 - 6 % of hemodialysis
patients and antibody levels correlated to blood access
thrombosis and change of access ( p<0.05 ) . -
pubmed
An unexpected finding was that of increased
heparin - induced platelet reactivity in 36 % of the control group of 24
uremic patients prior to dialysis or exposure to
heparin . -
pubmed
PARTICIPANTS : Optotype thresholds determination in three normal subjects and testing on 30 consecutive
patients with unclear
visual acuity loss . -
pubmed
A pocket chart was tested in a masked manner on 30 consecutive
patients referred because of unclear
visual acuity loss . -
pubmed
Ten percent ( 3 of 30 ) of the
patients referred because of unclear
visual acuity loss had to be excluded , because their diagnosis remained unclear . -
pubmed
All
patients ( 16 of 16 ) with organic
visual loss saw all optotypes sizes . -
pubmed
The first group ( n=6 ) was submitted to hysteroscopy and endometrial biopsy for metrorrhage , showing normal proliferative ( n=2 ) or secretory ( n=4 ) endometrium , the second group ( n=10 ) included
patients submitted to hysterectomy for endometrial
adenocarcinoma ( stages Ib - IIIb ) . -
pubmed
The mean
body weights of male
rats receiving 50,000 or 100,000 ppm and female
rats given 100,000 ppm were lower than those of controls . -
pubmed
Body weights of all groups of
mice were similar . -
pubmed
Kidney and liver weight to
body weight ratios for exposed
rats and
mice were greater than those for controls . -
pubmed
Centrilobular
hepatocellular hypertrophy was noted in male and female
mice receiving 20,000 and 50,000 ppm
acetone , respectively . -
pubmed
The final mean
body weights of
rats receiving 50,000 ppm were 19%percnt ; lower than that of controls for males and 7%percnt ; lower for females . -
pubmed
Liver and kidney weight to
body weight ratios were increased for male and female
rats receiving 20,000 ppm or greater . -
pubmed
Leukocytosis and
thrombocytopenia were observed at 20,000 ppm and above ( males and females ) , and
reticulocytopenia and
erythrocytopenia were seen at 5,000 ppm and above (
males ) . -
pubmed
Splenic pigmentation (
hemosiderosis ) noted in dosed
male rats was apparently related to these changes . -
pubmed
The increased incidence and severity of
nephropathy observed in dosed
male rats were considered the most prominent chemically related findings in this study . -
pubmed
The final mean
body weights of dosed and control
mice were similar . -
pubmed
The absolute liver weight and the liver weight to
body weight ratio were significantly increased for
females receiving 50,000 ppm , and the absolute spleen weight and the spleen weight to
body weight ratio were significantly decreased . -
pubmed
Centrilobular
hepatocellular hypertrophy of minimal severity was seen in 2110 female
mice receiving 50,000 ppm . -
pubmed
In 2002 , the reported numbers of
human and animal
infections increased , and the geographic range of
WNV activity expanded substantially . -
pubmed
These data underscore the need for intensive surveillance to detect and quantify
WNV activity in areas where
humans are at risk , public education to teach persons how to prevent mosquito
bites , and sustained and integrated mosquito - control activities . -
pubmed
A series of 10
cutaneous melanomas and 24 benign
melanocytic lesions with
patient records were independently examined for diagnosis confirmation and immunohistochemical expression by two dermatopathologists . -
pubmed
[ Experimental study on the formation of lung
metastasis in
ascites cancer of
mice ] . -
pubmed
Haemoglobinuria among adult
Nigerians due to
glucose-6 - phosphate dehydrogenase deficiency with drug sensitivity . -
pubmed
Bilateral occipital neuropathy as a rare complication of positioning for thyroid surgery in a morbidly obese
patient . -
pubmed
This is the first case report of temporary bilateral
occipital neuropathy from positioning for thyroid surgery in a morbidly obese
patient . -
pubmed
METHODS : A 48 - year - old
women with a history of
depression ,
fibro - myalgia ,
asthma ,
sleep apnea ,
diabetes mellitus and
morbid obesity ( 127 kg , 165 cm ) underwent 4 hours anesthesia with
propofol /
remifentanil without muscle relaxation for thyroid surgery . -
pubmed
Pressure from fat tissue during prolonged head extension for surgery seems to be the cause in this case and should therefore be avoided whenever possible in morbidly obese
patients , especially when other risk factors for
neuropathy like
diabetes are present . -
pubmed
RESULTS : Of the 155 patients , 144 fitted the clinical diagnosis of
tuberculosis , and 112 of them were culture positive for
M tuberculosis . -
pubmed
To determine whether there might be a biologic interaction between these two pathogens in vivo , we infected
mice with
Mycobacterium tuberculosis and then with a non - lethal
strain of
Plasmodium yoelii eight weeks later . -
pubmed
tuberculosis simulate the equilibrium between pathogen and host thought to exist in
human latent
infection . -
pubmed
RESULTS : The nerve was saved from peroperation damage in two
patients with
nervus laryngeus recurrens . -
pubmed
The third
patient with this deviation ended up with permanent unilateral
paralysis of the nerve , which indicated erroneous evaluation of nerve branches . -
pubmed
RESULTS : All
animals lacking both activities survived to the
hepatotoxic administration . -
pubmed
We analyzed the prognosis of 52
patients with
liver metastases from
colorectal cancer treated with
MCT as the first radical therapy . -
pubmed
Transformation of alternan - producing
strains of
Leuconostoc by electroporation . -
pubmed
METHODS : The results of treatment of
patients with symptomatic solitary non - parasitic
hepatic cysts treated between 1995 and 2000 were reviewed . -
pubmed
Five
patients were treated by laparoscopic fenestration ab initio as they also required a cholecystectomy because of
gallstones . -
pubmed
Biopsy specimens were taken from early
affected scalp lesions and paired with samples from clinically unaffected areas in the same
patient . -
pubmed
CONCLUSION : A descriptive , standardized histopathologic reporting of follicular architecture , type , location , and extent of the inflammatory infiltrate , and presence or absence of sebaceous glands , may be of greatest value in guiding the treatment of
patients with primary
cicatricial alopecias . -
pubmed
Inhibitory effects of
idoxifene on
hepatic fibrosis in
rats . -
pubmed
METHODS :
Hepatic fibrosis was induced by
dimethylnitrosamine (
DMN ) in male
rats . -
pubmed
RESULTS :
Idoxifene could markedly suppress
DMN - induced
hepatic fibrosis in
male rats . -
pubmed
CONCLUSION :
Idoxifene showed inhibitory action on
hepatic fibrosis in
male rats . -
pubmed
[ Nosohusial
infection by
Pseudomonas putida ] . -
pubmed
[ Effects of different levels of positive end expiratory pressure on lung recruitment and hemodynamics after sustained inflation in
acute respiratory distress syndrome in
sheep ] . -
pubmed
OBJECTIVE : To study the effects of different levels of positive end expiratory pressure ( PEEP ) on recruitment and hemodynamics after sustained inflation in
acute respiratory distress syndrome (
ARDS ) in
sheep . -
pubmed
METHODS : Twelve adult
sheep were anaesthetized and
ARDS was induced by lung lavage with warm normal saline . -
pubmed
For successful CPR of
trauma patients , a minimal intravascular volume status and management of
hypoxia are essential . -
pubmed
Despite bad prognosis , CPR in
trauma patients may be successful in select cases . -
pubmed
BACKGROUND : Elective colonoscopy is used increasingly to screen at risk
patients for
colonic malignancy . -
pubmed
Gamma - Hydroxybutyrate (
GHB ) ,
gamma - butyrolactone (
GBL ) , and
1,4 - butanediol (
1,4 - BD ) reduce the volume of
cerebral infarction in
rodent transient
middle cerebral artery occlusion . -
pubmed
We examined the potential neuroprotective effect of
GHB and its chemical precursors ,
gamma - butyrolactone (
GBL ) and
1,4 - butanediol (
1,4 - BD ) , in the
rodent ischemic stroke model by intraluminal filament
middle cerebral artery occlusion (
MCAO ) . -
pubmed
Adult male
Sprague - Dawley rats underwent transient left - sided
MCAO and received intraperitoneal treatment with 300 mg / kg of
GHB ,
GBL ,
1,4 - BD , or control vehicle given at 30 min before , as well as 180 and 360 min after the onset of
ischemia . -
pubmed
In transient
MCAO , the mean volume of
infarction for control
rats was 464.4 + /- 17.9 cu.mm versus 273.6 + /- 53.1 , 233.3 + /- 44.7 , and 275.4 + /- 39.9 cu.mm for
rats treated with
1,4 - BD ( P & lt ; 0.05 ) ,
GBL ( P & lt ; 0.05 ) , and
GHB ( P & lt ; 0.05 ) , respectively . -
pubmed
We conclude that
GHB ,
GBL , and
1,4 - BD protect against
rat focal
cerebral ischemia from transient
MCAO . -
pubmed
Quantitative sensory testing for spinal cord stimulation in
patients with chronic
neuropathic pain . -
pubmed
PARTICIPANTS : Thirteen
patients with
radicular leg pain due to
failed back surgery syndrome (
FBSS ) or
leg pain due to
complex regional pain syndrome (
CRPS ) who were candidates for SCS . -
pubmed
Selective loss of dentate hilar interneurons contributes to reduced synaptic inhibition of granule cells in an electrical stimulation - based
animal model of
temporal lobe epilepsy . -
pubmed
Neuropeptide - containing hippocampal interneurons and dentate granule cell inhibition were investigated at different periods following electrical stimulation - induced , self - sustaining
status epilepticus (
SE ) in
rats . -
pubmed
This loss may contribute to the reduced GABAergic synaptic inhibition of granule cells in
epileptic animals . -
pubmed
In secondary and sometimes in early latent
syphilis , antibodies reacted with high numbers of antigenic proteins of
T. - pubmed
CONCLUSION : The 1 - year incidence of
TMJ pain and/or dysfunction was high among 1st - year university
students . -
pubmed
Constituents in
rosemary have shown a variety of pharmacological activities for
cancer chemoprevention and therapy in in vitro and in vivo models . -
pubmed
In order to further explore the chemopreventive properties of crude extracts of
rosemary (
Rosmarinus officinalis L ) , we studied its anti - proliferative property on several
human cancer cell lines and its antioxidant and anti - inflammatory properties in vitro in a
mouse RAW 264.7 macrophage / monocyte cell line . -
pubmed
Our study shows that crude ethanolic rosemary extract ( RO ) has differential anti - proliferative effects on
human leukemia and
breast carcinoma cells . -
pubmed
On the other hand ,
LH cases showed extensive , predominantly lytic hepatocytic
necrosis ,
portal and hepatic vein phlebitis and morula cells in
patients with a morphological background of
chronic liver disease . -
pubmed
Risk factors for a
Blastocystis infection were drinking unboiled water , consumption of raw water plants and
pig ownership . -
pubmed
In conclusion ,
human Blastocystis was common in this village in southwest China , and different subtypes were associated with distinct transmission routes or sources of
infection , and hence Blastocystis subtypes might be linked to specific environmental compartments . -
pubmed
The objective was to evaluate the efficacy and
toxicity of
leucovorin plus
5 - fluorouracil combined with
oxaliplatin ( modified FOLFOX regimen ) every 2 weeks on previously untreated advanced
colorectal cancer patients in the Chinese population . -
pubmed
Toxicities were mild : five
patients ( 9.8 % ) reported grade 3 - 4
neutropenia , 33
patients ( 64.8 % ) experienced grade 1 - 3
neurotoxicity and only six
patients ( 11.8 % ) experienced grade 3
neurotoxicity . -
pubmed
The
leucovorin plus
5 - fluorouracil combined with
oxaliplatin ( modified FOLFOX ) regimen is active and well tolerated in
patients with previously untreated advanced
colorectal cancer in the Chinese population . -
pubmed
Characterization of
Trypanosoma cruzi isolated from
humans , vectors , and animal reservoirs following an outbreak of acute
human Chagas disease in Santa Catarina State , Brazil . -
pubmed
During March 2005 , 24 cases of acute
human Chagas disease were detected in Santa Catarina State , southern Brazil , all of them related to the ingestion of
Trypanosoma cruzi - contaminated
sugar cane juice . -
pubmed
Considering that mixed
strains ( TcI / TcII ) were isolated from triatomines in an area without active vectorial transmission to
humans and that all
strains isolated from
humans belong to the TcII group , our results show that
T. - pubmed
OBJECTIVE : To identify the complications and possible associated factors observed in
patients with suspected
prostate cancer undergoing transrectal ultrasound - guided ( TRUS ) biopsy . -
pubmed
The etiologies were heat
injury of the lateral malleolus in one
patient and
skin necrosis over the Achilles tendon attachment site in three
patients due to displaced calcaneal
fracture ,
pyogenic tendinitis of the Achilles tendon , and
vascular insufficiency of the wound after Achilles tendon surgery in a
patient with
Werner syndrome , respectively . -
pubmed
Postoperative complications included delayed
wound healing in one
patient and transient restriction of ankle motion in another
patient . -
pubmed
Hospital - acquired
methicillin - resistant
Staphylococcus aureus (
MRSA )
strains are no longer limited to acute - care hospitals but have now spread to other healthcare settings such as long - term - care facilities ( LTCFs ) , in most of which they are endemic . -
pubmed
Running activity increased gradually and was high in spontaneously
hypertensive rats ( SHR ) and
Sprague - Dawley rats , while low in
Wistar rats . -
pubmed
Patients with a clinical and radiographic diagnosis of
CAP were enrolled . -
pubmed
We report on two
FLSpCC patients treated with wide local excision and mastectomy associated with axillary lymph node dissection . -
pubmed
A comparative analysis found the vascular density in free liver
cyst walls was greater in
mice than in
humans . -
pubmed
The authors describe a
patient with
drop foot who had a compressed common peroneal nerve caused by
posterior fibular head dysfunction . -
pubmed
For
HIV positive patients , 11.7 % had
cerebral toxoplasmosis . -
pubmed
Twenty - one
patients presenting
toxoplasmic retinochoroiditis were treated by subconjonctival injections of
clindamycin and systemic corticotherapy at a dose of 1 mg / kg per day . -
pubmed
Predictors of the
recurrence of
hepatic encephalopathy in
lactulose - treated
patients . -
pubmed
METHODS :
Patients with
cirrhosis who were initiated on
lactulose after an index
hepatic encephalopathy episode in a liver - transplant centre were retrospectively reviewed . -
pubmed
Patients with / without
hepatic encephalopathy recurrence were compared , and predictors of
recurrence were analysed . -
pubmed
RESULTS : A total of 137
patients with
cirrhosis ( age 55 + /- 6years , MELD 17 + /- 7 ) who were initiated on
lactulose after the index
hepatic encephalopathy episode were included . -
pubmed
Of these , 103
patients developed recurrent
hepatic encephalopathy 9 + /- 1 months after their index episode ; 39 ( 38 % ) of these were not adherent on
lactulose , 56 ( 54 % ) were adherent and 8 ( 8 % ) had
lactulose - associated
dehydration leading to
recurrence . -
pubmed
Recurrent
hepatic encephalopathy precipitants in
lactulose - adherent
patients were
sepsis ( 19 % ) ,
GI bleeding ( 15 % ) ,
hyponatremia ( 4 % ) and
TIPS ( 7 % ) . -
pubmed
Glycemic control and the risk of
death in 1,484
patients receiving maintenance hemodialysis . -
pubmed
BACKGROUND : It is controversial whether tighter glycemic control is associated with better clinical outcomes in
people with
kidney failure . -
pubmed
How pDCs control peripheral immunetolerance and local parenchymal immune response and contribute to the altered immunoregulation in
autoimmune disorders in
humans is poorly understood . -
pubmed
To evaluate the potential immunoregulatory role of these two types of pDCs in
multiple sclerosis (
MS ) and other
human autoimmune disorders (
myasthenia gravis ) , we studied the phenotype and regulatory function of pDCs isolated from clinically stable , untreated
patients with
MS ( n = 16 ) . -
pubmed
Patients with
MS showed a reversed ratio of pDC1 / pDC2 in peripheral blood ( 4.4:1 in healthy controls , 0.69:1 in
MS ) , a phenomenon not observed in the other
autoimmune disorders . -
pubmed
Our data offer a plausible explanation for the disturbed immune tolerance in
MS patients and provide evidence that immunomodulatory therapy acts at the level of reconstituting homeostasis of pDC , thus reconstituting the disturbed balance . -
pubmed
In conclusion ,
ezetimibe 10mg / day add - on therapy may be safe and effective for treating
dislipidemia patients who have been treated with a statin . -
pubmed
However , the 3 autopsy
patients who were diagnosed with
NHLE on the basis of their typical clinical course died of complications . -
pubmed
After 24 months : 1 BMS , 2 SES
patients died ; 0
BMS , 0 SES
infarction ; 0
BMS , 0 SES stent
thrombosis and 3 BMS , 0 SES TVR between six and 24 months . -
pubmed
Between six and 24 months , neither stent
thrombosis occurred , nor repeat revascularisation was required in
patients who received a SES . -
pubmed
PURPOSE : The aim of this study was to evaluate treatment results in our
hypopharyngeal cancer patients . -
pubmed
PATIENTS AND METHODS : A total of three hundred and ninety five
hypopharyngeal cancer patients received radical treatment at our hospital ; 96 % were male . -
pubmed
All
patients received a CT scan or MRI for
tumor staging before treatment . -
pubmed
There was no significant difference in overall and
disease - specific survival rates between
patients who received radical surgery first and those who received
OPIT . -
pubmed
Thirty - seven
patients developed a second
malignancy , with an annual incidence of 4.6 % . -
pubmed
CONCLUSIONS : There was no survival difference between OPIT and radical surgery in
hypopharyngeal cancer patients at our hospital . -
pubmed
To discover how these changes are reflected at the level of gene expression , we used a subtractive transcription - based amplification of mRNA procedure to identify novel genes that have altered expression levels in the brains of
Alzheimer ' s disease (
AD )
patients . -
pubmed
METHODS : From September 2007 to September 2008 , 60
outpatients with stenosing
tenovaginitis of
flexor digitorum were randomized divided into the treatment group and the control group , 30 cases in each group . -
pubmed
The
patients were followed up for 6 months , and the relief of moving -
pain , tender -
pain , stretching -
pain and resist - ing --
pain were observed respectively . -
pubmed
Compared with the controls , the
patients given the combination were less likely to have
headaches after 7 days ( P = 0 038 ) , tended to have
headaches that cleared quicker ( P = 0 010 ) , and received fewer doses of
acetaminophen ( P = 0 036 ) . -
pubmed
Antibody recognition of
porcine circovirus type 2 capsid protein epitopes after vaccination ,
infection , and disease . -
pubmed
Baculovirus - based vaccines that express only ORF2 are protective against clinical disease following experimental challenge or
natural infection . -
pubmed
A retrospective case series of
bipolar patients with adjunctive
carbamazepine in long - term
lithium treatment : evaluation of the effectiveness . -
pubmed
From these results , more than 20 % of clinically normal and 97 % of diarrheic
rabbits were positive for single or concurrent
infection of three pathogens . -
pubmed
METHODS : We reviewed 36
schwannomas from 35
patients who underwent surgical excision of
schwannomas arising from the extremities . -
pubmed
The duration of symptoms , maximum
tumor diameter and site of occurrence were compared between
patients with the three grades of deficit . -
pubmed
RESULTS : In total , 22
patients developed no sensory changes following enucleation of
schwannoma or only temporary and minor changes that had fully resolved within 6 months . -
pubmed
Ten
patients developed new
neurological deficits following surgery that took longer than 6 months to resolve . -
pubmed
Four
patients experienced new motor deficits or
paresthesia following operation that had still not recovered at the final follow - up , all of whom underwent enucleation using the extra - capsular technique . -
pubmed
Patient age , duration of symptoms , maximum diameter of the
tumor and site of occurrence did not influence the
neurological deficit following enucleation of
schwannoma . -
pubmed
Thorough pre - operative counseling of
patients to inform them of the potential occurrence of
neurological deficit is important . -
pubmed
Endoscopic extraperitoneal radical prostatectomy ( EERPE ) is a well - established and standardized technique for treating
patients with
localized prostate cancer . -
pubmed
BACKGROUND : Age - specific comparisons of
influenza and
respiratory syncytial virus (
RSV ) hospitalization rates can inform prevention efforts , including vaccine development plans . -
pubmed
For each state and age group , we estimated the contribution of
influenza and
RSV to hospitalizations for respiratory and
circulatory disease by using negative binomial regression models that incorporated weekly
influenza and
RSV surveillance data as covariates . -
pubmed
Age - standardized annual rates per 100000 person - years varied substantially for
influenza ( 33 - 100 ) but less for
RSV ( 42 - 77 ) . -
pubmed
In recent years , the use of live microorganisms , such as viruses and
bacteria , has gained substantial research and clinical interest in both detection and therapy of
cancer . -
pubmed
CASE PRESENTATION : Case 1 was a 68 - year - old
man who was shown on radiography to have left lower calyx
calculi ( 19 x 15 mm , 7 x 5 mm , and 7 x 3 mm ) in
horseshoe kidney . -
pubmed
Case 2 was a 36 - year - old
woman shown on radiography to have a left lower calyx
calculus ( 10 x 8 mm ) in
horseshoe kidney . -
pubmed
RECENT FINDINGS : It is becoming apparent that the
skin inflammation alone has implications for systemic and
malignancy risk in
dermatomyositis patients , and that there may be several pathogenic similarities between muscle and
skin inflammation in
dermatomyositis . -
pubmed
SUMMARY : A more careful description and classification of
skin disease in
dermatomyositis may allow the clinician to predict more accurately which
patients will be at higher risk for
cancer ,
lung disease , or
muscle inflammation . -
pubmed
MATERIAL AND METHODS : The trial enrolled 83
patients ( 42 - 51 %
males , 41 - 49 %
females , mean age 46.7 years ) with stage II - IV
CKD of non - diabetic origin . -
pubmed
RESULTS :
LVH was detected in 31 ( 37.3 % ) of 83
patients . -
pubmed
Concentric remodeling , concentric
LVH , eccentric
LVH were detected in 31.3 , 19.3 and 18.1 %
patients , respectively . -
pubmed
CONCLUSION :
Patients with
renal dysfunction develop
LVH of different geometric model associated with both conventional and renal risk factors even at early stages of
CKD . -
pubmed
Due to their effectiveness as antifungal agents , three semisynthetic derivatives have been developed and approved for treatment of
human invasive candidiasis . -
pubmed
A comparison of coronary angiographic findings in
patients with and without prior
cerebral infarction . -
pubmed
Previous studies based on coronary angiography or computed tomography coronary angiography have demonstrated a high prevalence of
coronary stenosis in
patients with
cerebral infarction and no prior history of
coronary artery disease (
CAD ) . -
pubmed
The purpose of the present study was to compare the coronary angiographic findings of
patients with prior
cerebral infarction with those of
patients with no prior
cerebral infarction . -
pubmed
Consecutive
patients ( n = 126 ) who underwent a first coronary angiography for suspected
CAD but had no prior history of
CAD were classified into 2 groups , those with a clinical history of
cerebral infarction (
cerebral infarction group ) and those without a clinical history of
cerebral infarction (
noncerebral infarction group ) . -
pubmed
Thirty - four of 78
patients ( 44 % ) with
coronary stenosis did not have
angina symptoms . -
pubmed
Extracorporeal lung support in
patients with
chronic obstructive pulmonary disease . -
pubmed
Non - sex cord - stromal ovarian tumors frequently produce and secrete
estrogen in postmenopausal
women : impact on bone metabolism and abnormal endometrial histology . -
pubmed
OBJECTIVE : We investigated whether the
estrogen released from
non - sex cord - stromal ovarian tumors has biological effects on bone and endometrial tissue in postmenopausal
women . -
pubmed
Histological examinations of the endometrium were carried out in the 75
patients with
non - sex cord - stromal ovarian tumors . -
pubmed
Five ( 6.7 % ) of 75
patients with
non - sex cord - stromal ovarian tumors displayed abnormal endometrial histology , including 4
patients with grade 1 endometrioid
cancer . -
pubmed
15
patients had multiple stones , 10 pyelocalicial , 10 pelvic larger than 2 cm , 2 in
horseshoe kidneys and 3
staghorn stones . -
pubmed
Biochemical outcomes for
patients with intermediate risk
prostate cancer treated with
I-125 interstitial brachytherapy monotherapy . -
pubmed
BACKGROUND : The most common bariatric surgery , Roux - en - Y gastric bypass , leads to glycemia normalization in most
patients long before there is any appreciable
weight loss . -
pubmed
In vitro and in vivo anti - tumour effects of
MPT0B014 , a novel derivative
aroylquinoline , and in combination with
erlotinib in
human non - small - cell
lung cancer cells . -
pubmed
EXPERIMENTAL APPROACH :
Cytotoxicity in
human NSCLC cell lines was assessed by
sulforhodamine B and
3 -( 4,5 - dimethylthiazol-2 - yl )- 2,5 - diphenyltetrazolium bromide assays . -
pubmed
[
Dengue virus & amp ; co : are mosquito - borne
viral diseases on the rise ? ] -
pubmed
Postpartal subclinical
endometritis alters transcriptome profiles in liver and adipose tissue of dairy
cows . -
pubmed
Transcriptome alterations in liver and adipose tissue of
cows with
subclinical endometritis (
SCE ) at 29 d postpartum were evaluated . -
pubmed
RESULTS : Thirty - four out of 504
patients ( 6.8 % ) had incidental
prostate cancer with a mean age of 70.3 years . -
pubmed
Biochemical
recurrence occurred in 3
patients but no
prostate cancer - related
death during the follow - up . -
pubmed
BACKGROUND : The National Institutes of Health.funded Trial to Assess Chelation Therapy ( TACT ) randomized 1708 stablecoronary disease
patients aged .50 years who were .6 months
post.myocardial infarction ( 2003.2010 ) to 40 infusions ofa multicomponent
EDTA chelation solution or placebo . -
pubmed
CONCLUSIONS : In stable , predominantly asymptomatic
coronary disease patients with a history of
myocardial infarction ,
EDTA chelation therapy did not have a detectable effect on QOL during 2 years of follow - up . -
pubmed
A
bone failure was created in left parietal bone of adult male
mice . -
pubmed
After exclusion due to
death or
infection , thirty - eight
animals were evaluated ( BT=5 ; BM=6 ; BA=6 ; TCP=7 ; MDM=3 ; ALG=6 ; BAG=5 ) . -
pubmed
UNLABELLED :
Human papillomaviruses (
HPVs ) are small DNA viruses causally associated with
benign warts and
multiple cancers , including
cervical and head - and - neck cancers . -
pubmed
While the vast majority of people are exposed to
HPV , most instances of
infection are cleared naturally . -
pubmed
IMPORTANCE :
Human papillomaviruses (
HPVs ) are highly prevalent and potent
human pathogens that cause & gt;5 % of all
human cancers , including
cervical and head - and - neck cancers . -
pubmed
While the majority of people become infected with
HPV , only 10 to 20 % of
infections are established as persistent
infections . -
pubmed
Secondary endpoints included the number of
patients in whom the oral nutrition protocol was implemented successfully , as well as the number and type of
postoperative complications . -
pubmed
Up to 10 % of
patients with a benign
stricture are refractory to pneumatic dilatation and may benefit from biodegradable stent ( BD ) insertion . -
pubmed
Mean
dysphagia scores improved from 2.65 to 1.00 ( p value & lt;0.001 ) in benign disease and from 3.27 to 1.36 ( p value & lt;0.001 ) in
patients with malignant disease . -
pubmed
Distribution and treatment of
clavicular fractures in
monotrauma and
polytrauma patients . -
pubmed
BACKGROUND : Although extensive research for the optimal treatment of
clavicle fractures has been performed , comparative studies between
monotrauma and
polytrauma patients are lacking . -
pubmed
OBJECTIVE : To compare
fracture distribution and treatment in
monotrauma and
polytrauma patients with a
clavicle fracture . -
pubmed
Monotrauma patients sustained only a
clavicle fracture or a
clavicle fracture plus a minor
abrasion ,
hematoma , or
superficial skin lesion leading to an Injury Severity Score ( ISS ) of 4 or 5 respectively . -
pubmed
RESULTS : 154
monotrauma and 155
polytrauma patients with a
clavicle fracture were identified . -
pubmed
Monotrauma patients had a higher incidence of
Type IIB fractures (
displaced midshaft ) compared to
polytrauma patients ( P = 0.002 ) . -
pubmed
CONCLUSIONS :
Monotrauma patients had a higher incidence of displaced midshaft
clavicle fractures compared to
polytrauma patients , and
monotrauma patients with displaced midshaft
clavicle fractures were treated operatively more frequently . -
pubmed
Diminished
weight gain , impaired fat absorption , and elevated
steatorrhea occurred in KO
mice after instituting high - fat diet . -
pubmed
CONCLUSION : After SBR , KO
mice display an inefficient intestinal absorption profile with perturbed macronutrient transporter expression , impaired fat absorption , and slower postoperative
weight gain . -
pubmed
Posttraumatic seizures and
epilepsy in adult
rats after controlled cortical impact . -
pubmed
Posttraumatic epilepsy (
PTE ) has been modeled with different techniques of experimental
traumatic brain injury (
TBI ) using
mice and
rats at various ages . -
pubmed
We hypothesized that the technique of controlled cortical impact ( CCI ) could be used to establish a model of
PTE in young adult
rats . -
pubmed
Provoked class 3 - 5
seizures were recorded by video monitoring in 7/57 ( 12.3 % )
animals in the week immediately following CCI of the right parietal cortex ; none of the 7
animals demonstrated subsequent spontaneous
convulsive seizures . -
pubmed
Monitoring with video and/or video - EEG was performed on 128
animals at various time points 8 - 619 days beyond one week following CCI during which 26 ( 20.3 % ) demonstrated nonconvulsive or
convulsive epileptic seizures . -
pubmed
Nonconvulsive
epileptic seizures of & gt;10s were demonstrated in 7/40 ( 17.5 % )
animals implanted with 2 or 3 depth electrodes and usually characterized by an initial change in behavior ( head raising or
animal alerting ) followed by motor arrest during an ictal discharge that consisted of high - amplitude spikes or spike - waves with frequencies ranging between 1 and 2Hz class 3 - 5
epileptic seizures were recorded by video monitoring in 17/88 ( 19 % ) and by video - EEG in 2/40 ( 5 % )
CCI - injured animals . -
pubmed
These results indicate that the CCI model of
TBI in adult
rats can be used to study the structure - function relationships that underlie epileptogenesis and
PTE . -
pubmed
PATIENTS AND METHODS : In all , 1146 adult
patients with
renal or ureteric stones were treated at one urological centre using the latest model of the Modularis Vario lithotripter . -
pubmed
RESULTS : Between May 2007 and November 2009 , 698
patients with
renal stones and 448 with
ureteric stones underwent extracorporeal
shock - wave lithotripsy ( ESWL ) . -
pubmed
After 3 months , the success rate defined as the
patient being stone - free or with residual fragments of & lt;4 mm ; for
renal stones the rate was 91.1 % , with a 6.9 % complication rate in the form of steinstrasse and severe
renal colic . -
pubmed
Severe
OHSS can occur in
PCOS patients even after using a segmented approach i.e. -
pubmed
Patients at risk of
OHSS should be closely monitored following ovum pickup even when an agonist trigger has been given , for early detection and management . -
pubmed
The goal of this article is to convey an appreciation of these disorders because their recognition can benefit
patients tremendously , as
inflammatory lesions of the pancreas can be mass - forming , giving rise to
pseudotumors , and leading to surgical resection that may otherwise be unnecessary . -
pubmed
OBJECTIVE : To examine the incidence of
headache symptoms consistent with
migraine and
tension - type headache (
TTH ) in
children with
anxiety disorders . -
pubmed
METHOD : Parents of
children with
anxiety disorders ( n=27 ) and
children without
anxiety disorders ( n=36 ) completed a
headache questionnaire based on the International Classification of
Headache Disorders ( 2nd edition ) criteria . -
pubmed
RESULTS :
Children with
anxiety disorders had a higher incidence of
headache symptoms consistent with
migraine and
TTH compared to children without
anxiety disorders . -
pubmed
Girls with
anxiety disorders and children with
separation anxiety disorder had a higher incidence of
headaches compared to girls without
anxiety disorders and children with other
anxiety disorders respectively . -
pubmed
Children with
anxiety disorders and
headaches had higher self - reported
anxiety symptom severity compared to children with
anxiety disorders without
headaches and children without
anxiety disorders . -
pubmed
Spontaneous
flexor tendon rupture due to an
insufficiency fracture of the hamate hook in a
patient with
systemic lupus erythematosus : A case report . -
pubmed
CASE PRESENTATION : A 57 - year - old
woman was diagnosed with
SLE 22 years ago and being treated with oral
prednisolone . -
pubmed
CONCLUSION : When we encounter a case of spontaneous
flexor tendon rupture in a
patient with
systemic disease such as
SLE or long - term
steroid use , attention should be paid to the state of the carpal bones and joints as they sometimes accompany unexpected causes . -
pubmed
Partial characterization of bacteriocin - like compounds from two
strains of
Bacillus cereus with biological activity against
Paenibacillus larvae , the causal agent of American
Foulbrood disease . -
pubmed
American Foulbrood ( AFB ) , caused by the spore - forming Gram - positive bacterium
Paenibacillus larvae , is the most severe
bacterial disease affecting honeybees worldwide . -
pubmed
The most significant findings of this study are the characterization of bacteriocin - like compounds ( BLIS ) obtained from two
strains of
Bacillus cereus isolated from honey . -
pubmed
Both BLIS have a narrow activity range and highly inhibit the growth of
Paenibacillus larvae , the causal agent of American
Foulbrood disease of
honey bees . -
pubmed
Disbalance of
calcium regulation - related genes in
broiler hearts induced by
selenium deficiency . -
pubmed
Our objective was to investigate the effects of
Se deficiency on
Ca regulation - related genes in
broiler hearts . -
pubmed
In conclusion , the results demonstrated that
Se deficiency might cause
heart injury via modulating the
Ca - related pathway genes , and then induce
Ca2 + overload in the heart of
broilers . -
pubmed
Utility of plain radiographs and MRI in cervical spine clearance in symptomatic non - obtunded pediatric
patients without high - impact
trauma . -
pubmed
Currently , there is virtually no literature regarding imaging and management of symptomatic pediatric
patients who present with
cervical spine trauma without high - impact mechanism . -
pubmed
This study aims to establish an optimal imaging strategy for this subgroup of
trauma patients . -
pubmed
METHODS : We performed a retrospective review of pediatric
patients ( aged below 18 years ) who were admitted to Monash Medical Centre , Melbourne , Australia between July 2011 and June 2015 , who did not suffer a high - impact
trauma but were symptomatic for
cervical spine injury following
cervical trauma . -
pubmed
MRI was able to detect 4 cases of
ligamentous injury , which were not seen in CSS imaging and was able to facilitate cervical spine clearance in a further two
patients whose CSS radiographs were abnormal . -
pubmed
Veterinary radiologists who are aware of radiographic and imaging signs that result in
animal suffering , abuse , or neglect ; knowledgeable in ways radiology and imaging may support cause of
death determinations ; conversant in postmortem imaging ; comfortable discussing mechanisms and timing of blunt or sharp force and
projectile trauma in imaging ; and prepared to identify mimics of abuse can assist court participants in understanding imaging evidence . -
pubmed
Efficacy and safety of
nivolumab in Japanese
patients with previously untreated advanced
melanoma : A phase II study . -
pubmed
We carried out a single - arm , open - label , multicenter , phase II study to investigate the efficacy and safety of
nivolumab in previously untreated Japanese
patients with advanced
melanoma . -
pubmed
Treatment of
HCV is the mainstay of therapy for
mixed cryoglobulinemia syndrome , and newer
HCV therapies with direct - acting antiviral agents have achieved great success in treating
HCV infection compared with
pegylated interferon alfa and
ribavirin . -
pubmed
We report a case of recurrent mixed
cryoglobulinemia syndrome following
HCV treatment with a new direct - acting antiviral agent (
sofosbuvir ) and
ribavirin , in which
HCV RNA was undetectable in serum , but detectable in the cryoprecipitate . -
pubmed
RESULTS : Among the total 103
patients enrolled , 38 had disease complicated by
multiple organ dysfunction syndrome (
MODS ) . -
pubmed
Participants included 636 youth ( 338
girls , 298
boys ; X age in fourth grade = 9.95 , SD = .37 ) who completed measures assessing emotional clarity , stress responses , and
depressive symptoms . -
pubmed
valladaresi is a larger amoeba and although the
cysts are similar in size , there is no sign of the pore - like structures described in
L. - pubmed
Quantitative proteomic analysis of
murine white adipose tissue for
peritoneal cancer metastasis . -
pubmed
Cancer metastasis risk increases in older
individuals , but the mechanisms for this risk increase are unclear . -
pubmed
Because adipose tissue produces signals which influence several diseases including
cancer , proteomics of adipose tissue in aged and young
mice may provide insight into metastatic mechanisms . -
pubmed
INTRODUCTION : New treatments are required to improve clinical outcomes in
patients with
acute myocardial infarction (
AMI ) , for reduction of
myocardial infarct (
MI ) size and preventing
heart failure . -
pubmed
Pharmacological and genetic manipulation of these ncRNAs has the therapeutic potential to improve clinical outcomes in
AMI patients . -
pubmed
Functional outcomes of inpatient rehabilitation in very elderly
patients with
stroke : differences across three age groups . -
pubmed
Background As the population continues to age rapidly , clarifying the factors affecting the prognosis in very elderly
stroke patients is essential to enhance the quality of their rehabilitation . -
pubmed
Objectives To compare the functional recovery of elderly
stroke patients classified into three age groups and to identify the predictors of functional recovery in the very elderly following acute inpatient rehabilitation . -
pubmed
Methods Observational study : We collected data on 461
stroke patients in the neurology and neurosurgery ward and classified them into three age groups ( 65 - 74 , 75 - 84 , and & gt;= 85 years ) . -
pubmed
Conclusions This study identified the factors associated with functional recovery among very elderly
stroke patients . -
pubmed
Effective forms of rehabilitation for very elderly
stroke patients that take these factors into consideration need to be investigated . -
pubmed
METHODS : We interviewed 66
patients who acknowledged sensory changes during hypo /
manic states . -
pubmed
RESULTS :
Bipolar I patients were just as likely , if not more likely , to report suprasensory changes which typically involved enhancement of senses during hypo /
manic phases and muting or blunting during
depressive phases . -
pubmed
Here we explore the potential of a
tetraploid ( 2n = 4x = 68 ) interspecific hybrid
sunflower as a perennial oilseed for use in multifunctional agricultural systems . -
pubmed
A population of this novel
tetraploid was obtained from crosses between the annual diploid oilseed crop
Helianthus annuus ( 2n = 2x = 34 ) and the perennial hexaploid tuber crop
Helianthus tuberosus ( 2n = 6x = 102 ) . -
pubmed
These findings also offer insight into the mechanisms by which
chromosomal aberrations form during
human oogenesis and embryogenesis . -
pubmed
A short - cut review was carried out to establish whether a normal gait examination can rule out
cerebellar stroke in
patients with acute
vertigo . -
pubmed
A similar pattern of processing was also evident in tissue extracts from an invasive
ductal carcinoma patient . -
pubmed
Combining in vivo APT MRI measurements with ex vivo histological measurements of protein concentration in a
rat model of brain
metastasis , we determined that the proportion of APT MRI signal originating from changes in protein concentration was approximately 66 % , with the remaining 34 % originating from changes in
tumor pH. -
pubmed
In a
mouse model of
hypopharyngeal squamous cell carcinoma (
FaDu ) , APT MRI showed that a reduction in
tumor hypoxia was associated with a shift in
tumor pH. -
pubmed
The results of this study extend our understanding of APT MRI data and may enable the use of APT MRI to infer the pH of individual
patients '
tumors as either a biomarker for therapy stratification or as a measure of therapeutic response in clinical settings . -
pubmed
BACKGROUND : Over 80 % of
women with
X - linked adrenoleukodystrophy (
ALD ) develop
spinal cord disease in adulthood for which treatment is supportive only . -
pubmed
Moreover , diagnosis can be challenging in
ALD women , as the most important diagnostic biomarker is normal in 15 - 20 % . -
pubmed
The purpose of this single centre cross - sectional follow - up study in
women with
ALD was to assess whether Expanded Disability Status Scale ( EDSS ) , AMC Linear Disability Scale ( ALDS ) and Short Form ( 36 ) Health Survey ( SF-36 ) can detect
disease progression and to model the effect of age and duration of symptoms on the rate of progression . -
pubmed
For the pilot study we analysed plasma of 20
ALD women and 10 controls with ultra - high performance liquid chromatography coupled to high - resolution mass spectrometry , which identified 100 potential biomarker ratios with strong differentiating properties and non - overlapping data distributions between
ALD women and controls . -
pubmed
OBJECTIVES : Distinguishing between
kidney stones and phleboliths can constitute a diagnostic challenge in
patients undergoing unenhanced low - dose CT ( LDCT ) for
acute flank pain . -
pubmed
METHODS : Radiomics features were extracted following a semi - automatic segmentation of
kidney stones and phleboliths for two independent consecutive cohorts of
patients undergoing LDCT for
acute flank pain . -
pubmed
CONCLUSION : Radiomics and machine learning enable accurate differentiation between
kidney stones and
phleboliths on LDCT in
patients presenting with
acute flank pain . -
pubmed
Humans and
animals are widely and continuously exposed to
DEHP , especially with respect to diet , which is associated with
reproductive diseases . -
pubmed
Patients undergoing AXBF bypass were significantly more likely to be treated for
critical limb ischemia ( ABF bypass , 46.5 % ; AXBF bypass , 72.4 % ; HYB surgery , 51.8 % ; P & lt ; .001 ) under emergent conditions ( ABF bypass , 0.9 % ; AXBF bypass , 5.1 % ; HYB surgery , 3.6 % ; P & lt ; .001 ) . -
pubmed
HYB surgery
patients had significantly less
pneumonia ( ABF bypass , 8.7 % ; HYB surgery , 1.6 % ; P & lt ; .001 ) , unplanned intubation ( ABF bypass , 7.7 % ; HYB surgery , 3.1 % ; P = .032 ) ,
cardiac arrest ( ABF bypass , 3.7 % ; HYB surgery , 0.5 % ; P = .025 ) , transfusion ( ABF bypass , 44.4 % ; HYB surgery , 18.1 % ; P & lt ; .001 ) , and composite morbidity ( ABF bypass , 55 % ; HYB surgery , 32.6 % ; P & lt ; .001 ) . -
pubmed
This new approach will certainly improve
patient convenience and compliance , possibly resulting in broader acceptance and improved efficacy of
iloprost aerosol therapy in
PAH . -
pubmed
METHODS : A
mouse model of primary blast - induced
kidney injury was established using a custom - made explosive device . -
pubmed
INCLUSION CRITERIA : Primary diagnostic studies , published in English ; comparing red flags for
CES ; to Magnetic Resonance Imaging ( MRI ) as reference standard ; in
humans ; older than 18 years . -
pubmed
One hundred and ten paraffin - embedded tissue blocks ( 54 from
multiple sclerosis patients , 56 from non - neurological controls ) were matched to the diffusion tensor sequence to obtain regional diffusivity measures . -
pubmed
Five
patients aged between 42 and 62 were found to have Grade 1
hepatosteatosis . -
pubmed
METHODS : In this prospective single - center observational feasibility study , 30
cancer patients treated with palliative intent in an inpatient setting with an estimated life expectancy of & gt;8 weeks and & lt;12 months were provided with a smartphone including a pre - installed " Activity Monitoring " app and a sensor - equipped bracelet and monitored over a period of 12 weeks starting at discharge from hospital . -
pubmed
Materials and Methods : This prospective , single - center study enrolled 530
patients ( mean age 67.6 + -9.8 years ; 396
men ) undergoing endovascular procedures between August 2016 and July 2018 for chronic
PAD . -
pubmed
METHODS : Using total RNA from
human uterus
adenocarcinoma and
non - neoplastic uterus , we conducted a small RNA - sequencing experiment followed by prediction of novel miRNAs using MirDeep * software . -
pubmed
CONCLUSIONS :
Human tissues express an orthologue of
mouse miR-1839 - 5p and , given its expression pattern , we suggest that this miRNA could be explored as a potential oncomiR or
cancer marker . -
pubmed
Betulin attenuated
liver damage by prevention of hepatic
mitochondrial dysfunction in
rats with
alcoholic steatohepatitis . -
pubmed
The aim of this study was to evaluate the impact of liver mitochondria in hepatoprotection of
betulin using a
rat model of
alcoholic steatohepatitis induced by
ethanol administration ( 4 g / kg , intragastric ) for 8 weeks . -
pubmed
The increased susceptibility of mitochondria to
Ca2 + -induced permeability transition pore formation in the
hepatitis group was improved in
rats treated with
betulin . -
pubmed
In conclusion ,
betulin , having antioxidant properties , exerts a beneficial effect in the
rat model of
alcoholic steatohepatitis via prevention of
liver mitochondria dysfunction , which may be attributed to the inhibition of mitochondrial permeability transition . -
pubmed
Achieving sustained
HCV elimination is likely to require a combination approach including early access to DAAs in
acute infection and reinfection , validated and reproducible behavioural interventions and an efficacious
HCV vaccine . -
pubmed
RESULTS : The
pain Scale analysis showed that
patients in the RME group suffered from a significantly higher level of
pain than those in the LEAF group ( 88.6 % vs 25 % , p<0.01 ) . -
pubmed
Patients treated with Leaf Expander reported significantly lower
pain level in the first 7 days of treatment . -
pubmed
OBJECTIVE : To assess the risk of serious adverse events of
infections ( SAEI ) in
denosumab - treated
patients . -
pubmed
We excluded trials in
cancer patients for prevention of skeletal - related events . -
pubmed
Despite recently improved management of
LSCC , chemotherapy resistance of
patients remains a challenge . -
pubmed
Of the
plant - derived
n-3 FAs ,
SDA showed the greatest inhibition of
inflammation . -
pubmed
All the prediction models were validated using 70
non - small cell lung cancer (
NSCLC )
patients treated with volumetric modulated arc therapy ( VMAT ) . -
pubmed
Especially , from the results of the cellular morphology and proliferation of
human cancer stem cells ( hCSCs ) cultured on the
PEDOT nanofiber mats for 3 days , evidence was provided that the
PEDOT nanofiber mats have similar biocompatibility to tissue culture plates ( TCPs ) . -
pubmed
Successful Reduction of Intraocular Pressure in a
Patient with
Glaucoma Secondary to
Sturge - Weber Syndrome Using a Suprachoroidal Shunt . -
pubmed
Aim : We present a case of successful reduction of intraocular pressure ( IOP ) in a
patient with
Sturge - Weber syndrome (
SWS ) and moderate
open angle glaucoma using a suprachoroidal shunt . -
pubmed
Background :
Patients with
SWS glaucoma often have elevated episcleral venous pressure resulting in elevated IOP . -
pubmed
Case description : We present a case where a suprachoroidal shunt device ( CyPass ) was used to reduce IOP in a
patient with
SWS . -
pubmed
Clinical significance :
Glaucoma in
patients with
SWS has been historically difficult to treat . -
pubmed
Successful Reduction of Intraocular Pressure in a
Patient with
Glaucoma Secondary to
Sturge - Weber Syndrome Using a Suprachoroidal Shunt . -
pubmed
The present study included 23
relapsing - remitting MS (
RRMS )
patients , 23 seronegative
NMOSD patients , and 23 healthy age - matched controls between 18 and 45 years of age . -
pubmed
OBJECTIVE : This is the first investigation of the lipid - lowering and anti - atherosclerotic effects of
Ganoderma lucidum spore
ethanol extract ( EEG ) in
hyperlipidemic rabbits . -
pubmed
PATIENTS :
Adults and
children with
retraction pocket cholesteatoma . -
pubmed
Virulence and resistance determinants in
Pseudomonas aeruginosa isolated from
pericarditis in diseased broiler chickens in Egypt . -
pubmed
Objective : This study was performed to probe the antimicrobial resistance and virulence genes profiling in
Pseudomonas aeruginosa recovered from the cases of
pericarditis in broiler
chickens . -
pubmed
Materials and methods : The samples ( n = 250 ) collected from the cases of
pericarditis in broiler
chickens were bacteriologically examined . -
pubmed
aeruginosa recovered from
pericarditis in broiler chickens in the present study with
PAO1 ( reference
strain ) and with other sequences published on the GenBank representing different localities worldwide . -
pubmed
aeruginosa recovered from
pericarditis in broiler
chickens in the current study is highly virulent bacteria , resisting most of the therapeutic agents which not only bear hazards for poultry industry but also represent a public health concern . -
pubmed
Most
patients with
multiple myeloma (
MM ) will eventually relapse and current treatments have limited effect . -
pubmed
Their cytotoxic activities against
human lung cancer cells
A549 and
human breast cancer cells
MDA - MB-231 were evaluated using
MTT method . -
pubmed
All experimental
broilers were injected intraperitoneally with 0.5 mg / kg
body weight of either
Escherichia coli LPS or sterile saline at 16 , 18 , and 20 d of age . -
pubmed
We recruited 472
inpatients with chronic
SCZ ( 54
T2DM and 418 non -
T2DM ) , and 225 healthy controls . -
pubmed
SCZ patients with
T2DM scored higher in
delayed memory than
SCZ patients without
T2DM ( 77.17 + - 18.44 vs.66.24 + - 19.51 , p = 0.000 ) , and still showed significance after controlling for confounders . -
pubmed
Multivariate analyses ( after adjustment for other significant factors ) revealed that the changes in the abundance of
Hungatella hathewayi in the gut were significantly associated with the development of
eczema ( p = 0.005 ) . -
pubmed
In conclusion , the increased abundance of
Hungatella hathewayi was associated with an increased risk of developing
eczema by 1 year of age . -
pubmed
Terazosin and closely related drugs were recently discovered to enhance glycolysis and reduce
PD progression in animal models and
human clinical databases . -
pubmed
Patients in the Danish cohort who used
terazosin /
doxazosin /
alfuzosin had a hazard ratio ( HR ) for developing
PD of 0.88 ( 95 % CI , 0.81 - 0.98 ) , and patients in the Truven cohort had an HR of 0.63 ( 95 % CI , 0.58 - 0.69 ) . -
pubmed
Of the 179
patients diagnosed with a
stroke mimic on
TS , 27 ( 15 % ) were diagnosed with
AIS /
TA by discharge . -
pubmed
We performed a preliminary assessment of SISPA - nanopore sequencing as a potential approach for screening tick - borne viruses in six specimens with detectable
Crimean - Congo hemorrhagic fever virus (
CCHFV ) and
Jingmen tick virus (
JMTV ) sequences . -
pubmed
Isolation of a herpesvirus from the cell culture of a
malignant melanoma of a
ground squirrel (
Spermophilus tridecemlineatus ) . -
pubmed
On the basis of the literature and of their own investigations , including
animal experimentation , the authors attempt to show the possible causes of
death following lightning
strokes . -
pubmed
Animal experiments give evidence of the important role of
cardiac arrhythmias , in particular of
asystolia and
ventricular fibrillation . -
pubmed
[ Pathogenesis of
bone marrow necrosis in a
patient with
cancer ] . -
pubmed
Bone marrow necrosis was observed in a 23 - year - old pregnant
woman with severe
anemia and
thrombocytopenia due to bilateral
ovarian carcinoma . -
pubmed
Two
boys ( two years and a half old ) were admitted in this hospital for an
abdominal tumor . -
pubmed
[ A
hypophysis - abscess - syndrome in
cattle . -
pubmed
Two groups of subjects were studied : 24 healthy
volunteers ( 19 right - handed ) , and 53
patients ( 42 right - handed ) with autosomal dominant
FSHD . -
pubmed
Intratracheal instillation of
bleomycin in
hamsters initiates a series of events that mimic
human interstitial pulmonary fibrosis . -
pubmed
The cases of nine
patients who had a complex
fracture of the distal part of the femur and a deficient medial - cortical buttress were reviewed . -
pubmed
Additional stabilization with a medial plate and a bone graft from the iliac crest was applied in all nine
patients : in six , at the time of the index operation and in the remaining three , after the open
wound and open
fracture were considered clean . -
pubmed
Rat models showing similar
facial defects have already been described . -
pubmed
An asymmetric
deformity was produced which was similar to that occasionally seen in
man . -
pubmed
Although conventional wisdom holds that pharmacological interventions improve the haemodynamic and clinical status of
patients with chronic
heart failure by enhancing systolic performance , this hypothesis fails to explain many of the responses seen following the administration of these drugs . -
pubmed
This belief is supported by the following findings : ( 1 ) exercise capacity in chronic
heart failure is more closely related to left ventricular filling pressure than to cardiac output or limb blood flow ; ( 2 ) only drugs that lower left ventricular filling pressure have been shown to improve exercise capacity , whereas drugs that primarily increase cardiac output or left ventricular ejection fraction do not enhance effort tolerance ; ( 3 ) the primary mechanism by which vasodilator and inotropic drugs lower left ventricular filling pressure is by exerting a favourable effect on left ventricular diastolic function rather than on left ventricular volume ; ( 4 ) drugs that improve diastolic function tend to affect favourably the clinical status of
patients with chronic
heart failure , whereas drugs that adversely alter ventricular relaxation produce deleterious haemodynamic and clinical effects . -
pubmed
For our research ,
Bacillus pumilus spore strips and
vaccinia virus were used as more heat - resistant surrogates of the
human immunodeficiency virus (
HIV ) . -
pubmed
pumilus has defined cell
death values , whereas such values have not been established for
HIV . -
pubmed
The effects of negative regional lymph - node dissection on survival and disease - free interval of
patients with
stage - I malignant melanoma . -
pubmed
A group of 46
patients , with stage-1
malignant melanoma of intermediate thickness and histologically proven negative regional lymph nodes , was retrospectively reviewed . -
pubmed
A possible outbreak of
listeriosis caused by an unusual
strain of
Listeria monocytogenes . -
pubmed
During 1987 , a cluster of 23 cases of
listeriosis due to an unusual serotype of
Listeria monocytogenes was identified . -
pubmed
Oral
acyclovir reduces the incidence of recurrent
herpes simplex keratitis in
rabbits after penetrating keratoplasty . -
pubmed
To determine if
acyclovir sodium prevents postoperative
herpes simplex virus type 1 (
HSV-1 )
recurrences , 21
rabbits harboring latent
HSV-1 underwent uniocular autograft penetrating keratoplasty . -
pubmed
In addition , 9 ( 82 % ) of 11 of the operated - on eyes had
geographic ulcers develop in the non -
acyclovir - treated
rabbits , compared with 1 ( 10 % ) of 10 in the
acyclovir - treated
rabbits . -
pubmed
Finally ,
stromal keratitis appeared in 5 ( 56 % ) of 9 of the operated - on eyes in non -
acyclovir - treated
rabbits and 1 ( 12 % ) of 8 of the operated - on eyes in
acyclovir - treated
rabbits . -
pubmed
The results of this study indicate that
acyclovir significantly lowered the incidence of
HSV-1 ocular shedding ,
geographic ulceration , and
stromal keratitis in a
rabbit autograft penetrating keratoplasty model . -
pubmed
To clarify the relationship between
mitral regurgitation and
left ventricular outflow obstruction , Doppler and two - dimensional echocardiographic studies were performed in 62
patients with
hypertrophic cardiomyopathy ( 22 with and 40 without obstruction caused by mitral systolic anterior motion with septal contact ) . -
pubmed
Pulsed Doppler echocardiography with color Doppler flow imaging demostrated that in 20 of the 22
patients with obstruction ,
mitral regurgitation occurred mainly during midsystole from the onset to the end of mitral - septal contact . -
pubmed
A new modification in western blotting technique now permits the analysis of micro samples of blood collected from inhabitants of
malaria endemic areas using several different antigens of
Plasmodium falciparum . -
pubmed
It seems to open new prospects for seroepidemiological studies of
human malaria and for the selection of antigenic fractions that may allow the preparation of a vaccine . -
pubmed
We studied the changes in heart rate evoked during the Valsalva maneuver in 49 asymptomatic
Chagasic patients with different degrees of
myocardial involvement . -
pubmed
The
Chagasic patients were divided in three groups . -
pubmed
Sixteen
patients had a normal electrocardiogram but revealed evidence of localized
myocardial damage as shown by left ventricular cineangiography . -
pubmed
These results are in discordance with the commonly accepted hypothesis that cardiac parasympathetic denervation causes a
dilated myocardiopathy in
patients with chronic
Chagasic myocarditis . -
pubmed
[
Laryngeal papillomatosis in
children ] . -
pubmed
In vitro growth of
A431 human epidermoid carcinoma . -
pubmed
An examination of 80
patients with
ischaemic cerebrovascular disease , subdivided into 5 groups according to platelet antiaggregant treatment , demonstrated the insufficient effectiveness of
acetylsalicylic acid in preventing
recurrences . -
pubmed
In view of the fact that all our patients showed radiologically detectable
skeletal lesions of the head and neck , despite absence of symptoms in 35 per cent , it is advisable that all
patients with
von Recklinghausen ' s disease should routinely have radiological screening of this region , to detect early lesions . -
pubmed
A 3 - year - old
boy with segmental
stenosis of the distal trachea and a 2 - year - old girl with segmental
stenosis involving the carina and the right main bronchus were treated successfully with resection and reanastomosis . -
pubmed
Prevention of
cecitis in
hamsters by certain
prostaglandins . -
pubmed
Acute
inflammation of the colon (
cecitis ) was produced in
hamsters by daily subcutaneous administration of an antibiotic for 3 days . -
pubmed
Castor oil also prevented the
cecitis and
peanut oil exerted partial protection . -
pubmed
A straight - line relationship observed in the
death curve indicated a single target for
aflatoxin B1 action in
B. - pubmed
The involvement of plasma free
fatty acids in
( + ) - amphetamine - induced
hyperthermia in
rats . -
pubmed
Virilization superimposed on
Turner ' s syndrome : cytogenetic studies of a
gonadal tumor in a
patient with
XO - XY mixed gonadal dysgenesis . -
pubmed
An indirect E - rosette augmentation ( ERA ) assay was used to study cellular reactivity and tumour - related serum reactions in
mice bearing
methylcholanthrene (
MCA)-induced
tumours . -
pubmed
The organism , designated
strain 163 K , was isolated on modified Hayflick medium under aerobic conditions at 25 degrees C from the gills of a
tench (
Tinca tinca L. ) . -
pubmed
Study in Brattleboro
rats with
hereditary hypothalamic diabetes insipidus . -
pubmed
In all
patients bleeding stopped . -
pubmed
The nonspecific host defense system of 66
patients with
thermal injuries was studied prospectively . -
pubmed
Prognosis of sexual maturation in prepubertal
boys with
micropenis . -
pubmed
Long - term observations were made of the prognosis for sexual maturation ( onset of puberty ) in 15 prepubertal
boys with
micropenis . -
pubmed
Blood coagulation and fibrinolysis in fertile
women with previous
thromboembolic complications and effects of
venous occlusion . -
pubmed
It is also a useful staging procedure in selected
patients with
pulmonary and esophageal tumors . -
pubmed
We investigated the role of signal transduction systems in the attachment of
human uveal
melanoma cells to matrix proteins . -
pubmed
Echocardiographic prediction of the final event in
patients dying of
acute myocardial infarction . -
pubmed
From an autopsy series of 346
patients who died of
acute myocardial infarction , we selected 36 cases for whom echocardiographic data preceding
death were available : 17 cases died from a
rupture of the left ventricular free wall ( group A ) and 19 from
pump failure ( group B ) . -
pubmed
The results of treatment in twenty - seven
patients who had a
Ewing sarcoma of the pelvis were reviewed . -
pubmed
The actuarial over - all five - year survival was 45 per cent ( 23 to 65 per cent ) for all
patients who had had localized
disease when first seen . -
pubmed
Radiofrequency catheter ablation in pediatric
patients with
supraventricular arrhythmias . -
pubmed
A 38 year - old
man presented
fever and a clinical picture of
intracranial hypertension and
ataxic syndrome . -
pubmed
By 14 days after
injury , however , intimal area and SMC number were the same control and inhibitor - treated
rats . -
pubmed
An increased rate of SMC replication in the GM 6001
rats ( replication rates at 10 days were 56.7 + /- 10.0 % in the
GM 6001 group and 16.97 + /- 1.73 % in the control group ) contributed to " catch - up " growth of the
neointima . -
pubmed
Because the ductus arteriosus bridges the two vascular circuits in this lesion , we studied the Doppler echocardiographic flow patterns in the ductus arteriosus of 50
infants with
hypoplastic left heart syndrome to investigate their relationship to the degree of pulmonary blood flow as measured by simultaneously obtained levels of partial pressure of
oxygen in arterial blood . -
pubmed
Dysfunction in gastric myoelectric and motor activity in
Helicobacter pylori positive
gastritis patients with
non - ulcer dyspesia . -
pubmed
In Hp positive
patients before the triple therapy the mean fasted antral diameter was 4.3 cm2 , initial EGG showed significant
dysrhythmia of electrical control activity ( ECA ) with
tachygastria up to 25 % of recording time in 9 of 12 Hp positive
patients without normal increase of the power of signal in any of tested subjects . -
pubmed
We conclude that most symptomatic non
ulcer dyspeptic Hp positive
patients show changes in ECA and antral
hypomotility that are associated with
Hp infections . -
pubmed
Nondetectable cone and rod electroretinographic responses in a
patient with
Cockayne syndrome . -
pubmed
A total of 123
strains of
S hyodysenteriae and
S innocens were correctly identified by the colony blot assay whereas all the 26 non - Serpulina Gram - negative organisms commonly isolated from faecal material or tissues of
pigs remained negative . -
pubmed
DESIGN : Twenty - one adult female
mongrel dogs underwent either an open cholecystectomy , a laparoscopic cholecystectomy alone , or a laparoscopic cholecystectomy with
peritoneal injury ( n = 7 for each group ) . -
pubmed
Gastric dysrhythmias were observed in 23.8 % and 45.0 % of the
dogs on postoperative days 1 and 2 , respectively . -
pubmed
Adenovirus vector - mediated gene transfer into
human epileptogenic brain slices : prospects for gene therapy in
epilepsy . -
pubmed
As a first step in the development of a gene therapy approach to
epilepsy , we evaluated the ability of
adenovirus vectors to direct the transfer into and expression of a marker gene in
human brain slices obtained from
patients undergoing surgery for medically intractable
epilepsy . -
pubmed
Similarly , results of
irritability test demonstrated highest irritant behaviour of
An . - pubmed
Maturation of the Tract After Percutaneous Cholecystostomy with Regard to the Access Route Purpose : To assess the shortest time for catheter removal with regard to the transhepatic or transperitoneal approach in
patients undergoing percutaneous cholecystostomy ( PC).Methods : In this prospective study , 40 consecutive high - risk
patients with
acute cholecystitis ( calculous , n = 22 ; acalculous , n = 18 ) underwent PC by means of a transhepatic ( n = 20 ) or transperitoneal ( n = 20 ) access route . -
pubmed
The electrocochleographic recordings were carried out in 61
patients with a clinical diagnosis of
Meniere ' s disease and in 15 ears of normal hearing subjects . -
pubmed
Cytotoxicity levels in
human tumor cell lines were at comparable levels for several compounds . -
pubmed
The effect of
Cd2 + was similar , but
acidosis had less effect than in
rat myocytes ( e.g. -
pubmed
The data indicate that
acidosis and divalent cations influence Ito via a similar mechanism and act competitively in both
rat and
human myocytes , but that
human cells are less sensitive to the effects of
acidosis . -
pubmed
PATIENTS AND METHODS : Ten eyes of eight
patients with
chronic open angle glaucoma who had undergone erbium - YAG laser sclerostomy ab externo were examined using a UBM - probe with a 20 MHz transducer providing spatial resolution of approximately 80 microm . -
pubmed
Comparison of
genetic susceptibility to experimental allergic / immune - mediated
blepharoconjunctivitis between Lewis and Fischer
rats . -
pubmed
RESULTS :
Fischer rats developed mild
EAC compared with Lewis
rats . -
pubmed
CONCLUSION :
EAC in
Fischer rats was milder than that in Lewis
rats , although no apparent differences in immunological parameters between these two
strains were detected . -
pubmed
By using the
patient 's own cells , the procedure should obviate the need for immunosuppression and overcome the problem of tissue supply , while avoiding a
recurrence of cell destruction . -
pubmed
Importance of preoperative and postoperative pH monitoring in
patients with
esophageal achalasia . -
pubmed
We report the case of a
patient with synchronous
MPC of the lung , with
small cell carcinoma as the principal
tumor associated with
epidermoid carcinoma . -
pubmed
These data could suggest that the addition of a single new agent to a
platinum compound could be insufficient to substantially improve the prognosis of advanced
NSCLC patients . -
pubmed
In view of these disappointing data , the Southern Italy Cooperative Oncology Group has tried to improve the fate of
patients with advanced
NSCLC by testing new triplet combinations , which combined
cisplatin with two rather than one of the newest chemotherapy agents . -
pubmed
Evaluating the effectiveness of progressive muscle relaxation in reducing the
aggressive behaviors of
mentally handicapped patients . -
pubmed
This article reports the results of a study on the evaluation of the effectiveness of muscle relaxation training in reducing
aggressive behavior in
mentally handicapped patients ( MHPs ) . -
pubmed
Although the
syndrome of inappropriate anti - diuretic hormone secretion has been recognised as a complication associated with
burn and other
trauma in adults , relatively little is known about its incidence in
children . -
pubmed
The objective of this study was to investigate whether it is a complication associated with
burn injury in
children . -
pubmed
Recently ,
Mn was found to accumulate in brains of
cirrhotic patients who also present
motor abnormalities . -
pubmed
The relationship of
Mn content and DA turnover (
HVA : DA ) in the same
animal showed a positive and statically significant correlation ( P<0.05 ) , with differences in slope for sham ( b1=0.1528 ) and
cirrhotic rats ( b1=0.0174 ) . -
pubmed
These results suggest that
manganese brain accumulation observed in
liver failure could be a key element to understand
dopamine metabolism in cirrhotic condition of
humans . -
pubmed
Treatment of
attention deficit hyperactivity disorder in
children . -
pubmed
These are controversial times for those who care for
children with
attention deficit hyperactivity disorder (
ADHD ) . -
pubmed
Isolation and identification of pathogenic
strains of
Streptomyces acidiscabies from netted
scab lesions of
potato tubers in Hokkaido ( Japan ) . -
pubmed
A relatively homogeneous group of streptomycete isolates was obtained from netted
scab lesions of
potato tubers collected from a
potato field in Hokkaido , Japan . -
pubmed
Based on 55 phenotypic data of 72 Streptomyces
strains selected from these isolated together with spectral data on their soluble pigments and with data of a PCR analysis , using species specific primers , these netted scab causing pathogenic organisms were identified as
S. - pubmed
[ Correlation of endotracheal tube biofilm and recurrent
ventilator - associated pneumonia with
Pseudomonas aeruginosa ] . -
pubmed
In the present review , the authors summarize experiences with covered stents , and focus attention on available data on the implantation of
PTFE - covered stents in
human beings to treat
coronary ruptures ,
aneurysms and aortocoronary
vein graft stenosis . -
pubmed
Circulating T - lymphocyte activation in
patients with
variant angina . -
pubmed
DESIGN : To elucidate the role of systemic immune and inflammatory responses in the pathogenesis of
coronary spasm , we studied circulating T - lymphocyte activation in
variant angina patients (
VAPs ) , stable
effort angina patients (
EAPs ) and in control participants . -
pubmed
METHODS : Twenty documented
VAPs , 13
EAPs and 20 control
participants were studied . -
pubmed
Treatment - induced
anaemia and its potential clinical impact in
patients receiving sequential high dose chemotherapy for metastatic
testicular cancer . -
pubmed
First - line sequential high dose chemotherapy is under investigation in
patients with " poor prognosis "
metastatic germ cell tumours in order to improve survival . -
pubmed
This study investigates the frequency and degree of
anaemia in
patients receiving first - line sequential high dose chemotherapy for metastatic
testicular cancer and the impact of
anaemia on treatment outcome . -
pubmed
A total of 101 newly diagnosed
patients with " poor prognosis "
metastatic nonseminomatous germ cell tumours were treated with one cycle of standard VIP followed by three cycles of HD - VIP - chemotherapy (
etoposide ,
ifosfamide ,
cisplatin ) within a large phase I / II study . -
pubmed
Severe
anaemia is a very frequent side effect of sequential dose intensive therapy in
patients with
germ cell cancer , with almost all
patients becoming transfusion dependent . -
pubmed
We performed a detailed retrospective clinicopathologic analysis of 43
patients who underwent LT for
PBC . -
pubmed
Patients with no recurrent disease had shorter follow - up periods and more frequent immunosuppression , including
AZA ; some may still develop
recurrence with longer follow - up . -
pubmed
Surviving spleen graft rejected the
lymphoma cells , but not in
rats rejected the graft . -
pubmed
Alefacept therapy produces remission for
patients with
chronic plaque psoriasis . -
pubmed
In a previously published randomized , placebo - controlled phase II study of intravenous alefacept in 229
patients with
chronic plaque psoriasis , clinical improvement was observed during dosing as well as in the postdosing follow - up period . -
pubmed
Of 48
patients , 30 had suspected precancerous or
cancerous laryngeal lesions , 7 presented benign
laryngeal lesions , while 8 showed pharyngeal and 3
oral tumors . -
pubmed
METHODS : The sera from 65
patients with
colorectal cancer ( 18 at Dukes ' B , 24 at Dukes ' C , 23 at Dukes ' D ) were extracted before treatment . -
pubmed
The aim of this study was to investigate the metabolic correlates of these deficits in a group of non - selected consecutive
patients with
frontal lobe lesions . -
pubmed
PATIENTS AND METHODS : Clinicometabolic correlations between several emotional and social parameters and metabolic patterns in the frontal cortex and amygdala were investigated in 32
patients with
frontal lobe pathologies . -
pubmed
Pain -
spot densities in
human skin ; an experimental study . -
pubmed
Recovery after
anaphylaxis of isolated
guinea pig ileum segments . -
pubmed
The aim of this study was to determine the effects of improvements in
urinary incontinence resulting from pelvic floor rehabilitation on the sexual function of
patients . -
pubmed
To evaluate whether changes in surgical technique have influenced this pattern of
recurrence , a multicenter retrospective analysis was carried out on a
patient population treated recently . -
pubmed
Cloning of the
mouse obesity gene in 1994 is perhaps the most famous impetus for recognition that adipocytes are active in the regulation of multiple body functions . -
pubmed
Fetus - in - fetu (
FIF ) is a rare
congenital condition in which a
vertebrate fetus is incorporated within its twin . -
pubmed
Epidemiology and risk factors of
transmissible spongiform encephalopathies in
man . -
pubmed
Currently 60 % of
patients with
primary hyperparathyroidism can benefit of these techniques . -
pubmed
In Part 2 , relevant data on the development of intestinal adaptation in studies involving
humans will be reviewed as will the general management of
SBS . -
pubmed
METHODS : The
patients were retrospectively divided into two groups ( hypolordotic and
hyperlordotic ) using the lumbar
lordosis on lateral lumbosacral view . -
pubmed
DESIGN AND METHODS : We analyzed 1180 consecutive
patients with
leukemia ( n=979 ) or other
hematologic malignancies ( n=201 ) undergoing HSCT in 4 time periods : before 1990 , 1991 - 1995 , 1996 - 2000 , and 2001 - 2002 . -
pubmed
This is a consequence of reductions in
GvHD ,
infections and
multiorgan failure among
patients in remission but not among those who relapse . -
pubmed
There has been no improvement in survival for
patients beyond first remission , due to persisting high risk of
infections and
organ toxicity , a possible consequence of prolonged pre - transplant chemotherapy and
neutropenia . -
pubmed
kleinii the
pentacyclic triterpene alpha - amyrin , all caused a dose - related inhibition of both
ear oedema ( ID50 values are 0.55 and 0.31 mg / ear , respectively ) and influx of polymorphonuclear cells ( ID50 values are 0.72 and 0.45 mg / ear , respectively ) in response to topical application of
12 - O - tetradecanoylphorbol - acetate (
TPA ) in the of
mice ear . -
pubmed
In a
rat model , warm
ischemia of the left lateral liver lobe was induced for 90 minutes under intraperitoneal anesthesia with xylazine and
ketamine . -
pubmed
We tested the hypothesis that small airway reticular basement membrane thickening exists even in clinically stable lung transplant
recipients with some evidence of
inflammation but who are BOS - free . -
pubmed
Ursolic acid inhibits
neointima formation in the
rat carotid artery injury model . -
pubmed
Administration of
ursolic acid in the
rat carotid balloon catheter
injury model shows a significant inhibition of
neointimal hyperplasia . -
pubmed
In vitro activity of
tigecycline against isolates from
patients enrolled in phase 3 clinical trials of treatment for complicated skin and skin - structure
infections and complicated
intra - abdominal infections . -
pubmed
Tobacco use and
stomach cancer in Mizoram , India . -
pubmed
Tuibur (
tobacco smoke - infused water ) , used mainly in Mizoram , was seemed to increased the risk of
stomach cancer among current users in both univariate and multivariate models ( OR , 2.1 ; 95 % CI , 1.3 - 3.1 ) . -
pubmed
Tobacco use in any form [ smoking and smokeless ( tuibur and chewing ) ] increased the risk of
stomach cancer in Mizoram independently after adjusting for confounding variables . -
pubmed
Because acute
hemolysis is caused by exposure to an oxidative stressor in the form of an
infection , oxidative drug , or
fava beans , treatment is geared toward avoidance of these and other stressors . -
pubmed
Furthermore , in a trial conducted in
patients with
corticosteroid - induced
osteoporosis , intermittent i.v . -
pubmed
These simple
ibandronate regimens are expected to provide the optimal combination of efficacy , tolerability and
patient convenience , leading to improved treatment adherence and thus , enhanced outcomes in postmenopausal
osteoporosis . -
pubmed
Immune cell apoptosis may play a role in
human persistent
Helicobacter pylori infection . -
pubmed
PATIENTS : Forty - eight
patients ( 34 females and 14 males ) with a histologically confirmed diagnosis of appendiceal
carcinoid were included in the study . -
pubmed
Appendiceal
carcinoid was diagnosed incidentally in all 48
patients . -
pubmed
Following review of the literature , we were unable to find any recent evidence of distant
metastasis from
carcinoids in
patients already treated by appendectomy . -
pubmed
Fatty acids of
rice coleoptiles in air and
anoxia . -
pubmed
However , there is still much unknown regarding the nature and concentration of
RCOs in
HD patients . -
pubmed
This study was designed to evaluate the level of toxic
aldehydes in the plasma of
HD patients and to determine the extent to which these
aldehydes contribute to RCO
toxicity among these
patients . -
pubmed
METHODS : 15
aldehydes of the
alkanal ,
alkenal and
4 - HO - alkenal type were measured in the plasma of 17
HD patients and 20 healthy controls . -
pubmed
CONCLUSION : The increased levels of
alkanals ,
alkenals and
4 - HO - alkenals of lipid peroxidation in the plasma of
HD patients may greatly contribute to the toxicity of
RCOs . -
pubmed
Scarless skin repair in
immunodeficient mice . -
pubmed
Scarring , the end result of the
wound healing process in adult
mammals , is a problem of significant clinical importance . -
pubmed
We observed that
athymic nude - nu mice , similar to
mammalian fetuses , are able to restore the structure and integrity of injured skin through a process resembling regeneration , where
scar formation is absent . -
pubmed
CONCLUSION : Term
infants with a low Apgar score have
cochlear impairment , mainly at the frequencies 1 - 3 kHz . -
pubmed
OBJECTIVE : To detect any
peripheral impairment of cochlear origin in
infants with a low Apgar score . -
pubmed
SUBJECTS AND METHODS : Fifty - four term
infants with a low Apgar score at 1 and/or 5 min but without clinical signs of
hypoxic - ischaemic encephalopathy were recruited . -
pubmed
MATERIAL AND METHODS : A summary is given from recently published meta - analyses on three possible clinical applications of
human papillomavirus (
HPV)-DNA testing : triage of women with equivocal or low - grade cytological abnormalities ; prediction of the therapeutic outcome after treatment of
cervical intraepithelial neoplasia (
CIN ) lesions , and last not but not least , primary screening for
cervical cancer and pre -
cancer . -
pubmed
After treatment of cervical
lesions ,
HPV testing easily detects ( with higher sensitivity and not lower specificity ) residual or recurrent
CIN than follow - up cytology . -
pubmed
CONCLUSIONS : Sufficient evidence exists to recommend
HPV testing in triage of women with atypical cytology and in surveillance after treatment of
CIN lesions . -
pubmed
Cognitive functions in
patients with
MR - defined chronic focal
cerebellar lesions . -
pubmed
The aim of the present study was to examine cognitive functions in a group of chronic
patients with focal
cerebellar lesions . -
pubmed
Fourteen
patients with
infarctions within the territory of the posterior inferior cerebellar artery ( PICA ) and seven
patients with
infarctions within the territory of the superior cerebellar artery ( SCA ) participated . -
pubmed
The right cerebellar hemisphere was affected in eight PICA and two
SCA patients , the left hemisphere in six PICA and four
SCA patients . -
pubmed
One
SCA patient revealed a bilateral lesion . -
pubmed
In sum , the results showed preserved cognitive abilities in chronic cerebellar
patients apart from
impairments of verbal fluency in
patients with
right - cerebellar lesions . -
pubmed
The discovery of epigenetic silencing as a key mechanism of
tumor suppressor gene inactivation in
human cancer has led to great interest in utilizing epigenetic modulatory drugs as
cancer therapeutics . -
pubmed
Recent work has begun to dissect the specific epigenetic mechanisms controlling differential expression of CG antigen genes in
human cancers . -
pubmed
Taken together , these data encourage clinical evaluation of combination therapies involving epigenetic modulatory drugs and CG antigen - directed
tumor vaccines for the treatment of
human malignancies . -
pubmed
OBJECT : The purpose of this study was to measure the dose of radiation delivered to the cochlea during a Gamma knife surgery ( GKS ) procedure for treatment of
patients with
vestibular schwannomas (
VSs ) , and to analyze the relationship between cochlear irradiation and the hearing outcome of these
patients . -
pubmed
METHODS : Eighty - two
patients with
VSs were treated with GKS using a marginal dose of 12 Gy . -
pubmed
CASE PRESENTATION : A 70 - year - old
male underwent low anterior resection with total mesorectal excision for a rectal
adenocarcinoma . -
pubmed
Atomoxetine increases
histamine release and improves
learning deficits in an
animal model of
attention - deficit hyperactivity disorder : the spontaneously
hypertensive rat . -
pubmed
To that end , the aim of our study was to investigate the effect of
atomoxetine ( 2 mg / kg , intraperitoneally ) on
histamine release using the microdialysis technique in the spontaneously
hypertensive rat ( SHR ) , a suitable genetic model for
ADHD . -
pubmed
Chronic schizophrenic patients with a long - term disease process and medication period have not been investigated so far . -
pubmed
Subsequently ,
AG014699 dose was fixed at PID and
temozolomide escalated to maximum tolerated dose or 200 mg / m2 in metastatic
melanoma patients whose
tumors were biopsied . -
pubmed
Improved prognosis of
patients with
primary biliary cirrhosis that have a biochemical response to
ursodeoxycholic acid . -
pubmed
BACKGROUND & amp ; AIMS :
Ursodeoxycholic acid (
UDCA ) improves laboratory liver test results in
patients with
primary biliary cirrhosis (
PBC ) . -
pubmed
We performed a prospective multicenter study of
patients with
PBC treated with
UDCA to compare prognosis with biochemical response . -
pubmed
CONCLUSIONS : Prognosis for
UDCA - treated
patients with early
PBC is comparable to that of the general population . -
pubmed
At the same time ,
human neural stem cells ( hNSC ) were transfected under different multiplicity of
infection . -
pubmed
These
mice show
myometrial hyperplasia and develop
mesenchymal tumors with 100 % penetrance that exhibit histological and molecular characteristics of
human leiomyomas and
endometrial stromal sarcomas . -
pubmed
Additionally ,
adenomyosis and
endometrial gland hyperplasia were occasionally observed in some
mice . -
pubmed
Testing for the reappearance of lesions after injection of the
patient 's own erythrocytes is usually useful for the diagnosis of
AES , but the significance of this test is still controversial . -
pubmed
We report a 28 - year - old
woman who presented recurrent episodes of
painful purpura with
vertigo and hemilateral
auditory impairment after difficulties at her workplace . -
pubmed
These findings suggest that treatment for
psychological disorders is important in
patients with
AES . -
pubmed
METHODS : From Jan 2005 to Dec 2006 , 31 selected
patients ( 22
males and 9
females , aged from 41 to 63 years ) with
degenerative lumbar diseases were treated with minimally invasive TLIF assisted by METRx X - Tube micro - endoscopy system . -
pubmed
METHODS : Three
patient groups totalling 28 subjects with
diabetes [ group A 10 Type 1 ( Ulm ) , group B 10 Type 1 ( Neuss ) , group C eight Type 2 ( Aarhus ) ] participated in this trial . -
pubmed
The average absolute differences were 1.14 mmol / l for Type 1 and 0.88 mmol / l for Type 2
diabetic patients . -
pubmed
Relative absolute differences were 16.0 % for Type 1 and 12.6 % for
Type 2 diabetic patients . -
pubmed
CONCLUSIONS : These results demonstrate that this microdialysis system allows reliable continuous
glucose monitoring in
patients with
diabetes of either type . -
pubmed
PURPOSE : To evaluate a
low vision rehabilitation service implemented for heterogeneously diverse group of
Egyptianpatients with
vision loss in terms of improving their visual performance and fulfilling their visual needs . -
pubmed
METHODS : Fifty
patients with
low vision were included in a prospective study . -
pubmed
OBJECTIVE : The purpose of this study was to evaluate contrast - enhanced ultrasound and neural network data classification for determining the
breast cancer response to
bevacizumab therapy in a
murine model . -
pubmed
Twenty - five
nude athymic mice with orthotopic
breast cancers received a 30 - microL tail vein bolus of a
perflutren microsphere UCA , and baseline
tumor imaging was performed using microbubble destruction - replenishment techniques . -
pubmed
RESULTS : The
breast cancer response to a single dose of
bevacizumab in a
murine model was immediate and transient . -
pubmed
DESIGN AND METHODS : Sixty - nine untreated
adults with
T - cell acute lymphoblastic leukemia were evaluated by oligonucleotide arrays : unsupervised and supervised analyses were performed . -
pubmed
Of these , one branch included seven
patients whose gene expression profile resembled that of
acute myeloid leukemia . -
pubmed
Using one functional single- nucleotide polymorphism ( SNP ; rs6295 ) and one tagging SNP ( rs878567 ) , we conducted a genetic association analysis of case - control samples ( 857
schizophrenic patients , 1028
BP patients and 1810 controls ) in the Japanese population . -
pubmed
Here , we investigated whether alterations in endocannabinoid ( eCB ) signaling in the NAc contribute to
depression - like behaviors induced by chronic unpredictable stress ( CUS ) in
mice . -
pubmed
[ Preventive
relapse treatment for
tobacco cessation - is it worthwhile ? ] -
pubmed
We herein provide a selected overview of
tobacco relapse prevention strategies evaluated in different trials and in a recent meta - analysis . -
pubmed
Currently there is insufficient evidence to recommend systematic preventive
relapse treatment for
tobacco addiction with psychological or pharmacological interventions . -
pubmed
Extended treatment with
Varenicline may reduce
relapse rates following
tobacco cessation . -
pubmed
Further meticulously designed and appropriately powered trials will be necessary to clarify the role of alternative psychological and pharmacological strategies for the prevention of
relapse after
tobacco cessation . -
pubmed
Moreover , VB-201 , an orally available synthetic phospholipid analog of the
Lecinoxoid family , was found to attenuate
inflammation in various preclinical
animal models and is currently employed in a phase II clinical trial in
psoriasis . -
pubmed
We present the first evidence for the uptake of
nodularin by a terrestrial plant , and show that the exposure of
spinach to cyanobacterial crude water extract from
nodularin - producing
strain AV1 results in inhibition of growth and bleaching of the leaves . -
pubmed
Treatment of
mice with
Sphingomab resulted in blood B and T cell
lymphopenia . -
pubmed
No benefit of a proximal stem centralizer in cementing of a femoral prosthesis in
human cadavers . -
pubmed
A total of 136 faecal samples from
buffalo ( n = 122 ) and
cow calves ( n = 14 ) exhibiting clinical signs of
diarrhoea and from healthy calves were collected during 2007 - 2010 from subtropical ( central India ) and tarai area of western temperate Himalayan foothills ( Uttarakhand ) . -
pubmed
Among the five
PBV samples identified , three were from buffalo calves and one from
cow calf exhibiting clinical signs of
acute diarrhoea , while one sample from non - diarrhoeic buffalo calf also showed the presence of
PBV . -
pubmed
None of the samples showed dual
infection of rotavirus and
PBV . -
pubmed
The preliminary findings indicate sporadic incidences of
PBV in
bovine calves and emphasize the need for the development of better diagnostics for early detection and genetic characterization of these emerging isolates of farm animals of economic significance . -
pubmed
Previously , we demonstrated that reproductive senescence was associated with
mitochondrial deficits comparable to those of female triple - transgenic
Alzheimer 's
mice ( 3xTgAD ) . -
pubmed
Depletion of ovarian hormones by ovariectomy ( OVX ) in nontransgenic
mice significantly decreased brain bioenergetics , and induced
mitochondrial dysfunction and oxidative stress . -
pubmed
These findings provide a plausible mechanism for increased risk of
Alzheimer ' s disease in premenopausally oophorectomized
women while also suggesting a therapeutic strategy for prevention . -
pubmed
We report a case involving a 34 - year - old
woman who presented with a persistent
skin rash over her neck and upper body , with clinical features suggestive of
dermatomyositis . -
pubmed
Hematologic changes after total body irradiation and autologous transplantation of hematopoietic peripheral blood progenitor cells in
dogs with
lymphoma . -
pubmed
Dogs with and without
lymphoma have undergone hematopoietic cell transplantation in a research setting for decades . -
pubmed
All
dogs had & gt;= 500 neutrophils / mul by day 12 , while
thrombocytopenia persisted for many weeks . -
pubmed
502
patients will be recruited and randomized into two arms :
patients in arm A will receive IMRT in 28 fractions delivering 50.4 Gy to the breast and 64.4 Gy to the
tumor bed by integrated boost , while
patients in arm B will receive conventional radiotherapy of the breast in 28 fractions to a dose of 50.4 Gy and consecutive boost in 8 fractions to a total dose of 66.4 Gy . -
pubmed
Epidemiological data indicate that low serum
vitamin D concentrations are associated with an increased risk of a variety of
human tumours . -
pubmed
Cutaneous mast cell tumours (
MCT ) occur more frequently in
dogs than in any other species . -
pubmed
To examine this association , serum
25 - hydroxyvitamin D3 (
25 ( OH ) D3 ) concentrations were examined in eighty - seven
Labrador retrievers , including thirty - three with
MCT and fifty - four unaffected controls . -
pubmed
OBJECTIVES : We describe the clinical presentation of a 7 1/2 - year - old
boy with a history of mild intermittent
asthma who presented with left
lung collapse and was found to have
plastic bronchitis . -
pubmed
METHODS : We reviewed the
patient chart and imaging results and performed a literature review of
plastic bronchitis and its management . -
pubmed
MATERIAL AND METHOD : Between 2009 and 2010 , 90
cases with
MG , treated at the adult neurology service of King Chulalongkorn Memorial Hospital were consecutively recruited . -
pubmed
Graft /
patient status was classified as stable , serious
infection , or
malignancy . -
pubmed
IFT levels were analyzed with duration of follow - up after OLT , graft /
patient status , and the presence of
hepatitis C ( HCV ) infection . -
pubmed
Clinically stable
patients had higher IFT levels than those with serious
infection or
malignancy ( 254 + -11.1 vs. 162.5 + -23.9 , p<0.001 ) . -
pubmed
Fresh
vegetables , fruit and fish provide protection from
OSCC . -
pubmed
Management of
patients with
OPMD and treated
OSCC include careful life - long follow - up . -
pubmed
This international , randomized , placebo - controlled , double - blinded phase III trial examines the efficacy and safety of
ramucirumab treatment administered in combination with
docetaxel , as compared with
docetaxel administered with placebo , in
patients with stage IV
non - small - cell lung cancer (
NSCLC ) whose disease progressed during or after first - line
platinum - based chemotherapy with or without maintenance treatment . -
pubmed
Both drugs are administered via intravenous infusion once every 3 weeks until evidence of
disease progression , unacceptable
toxicity , noncompliance , or
patient 's consent withdrawal . -
pubmed
Efficacy and safety will be compared between the study arms and in
patient subgroups including
patients with nonsquamous versus squamous
tumor histology and
patients who received prior
bevacizumab treatment . -
pubmed
The goal of the REVEL study is to demonstrate that
ramucirumab in combination with
docetaxel improves overall survival of
patients with
NSCLC with progressive disease after first - line therapy , and to advance our knowledge of the role of angiogenesis blockade in
patients with
NSCLC by identifying
patients who are likely to experience maximum benefit based on extensive clinical biomarker correlative analysis . -
pubmed
[ Nonpharmacological methods of prevention of
thromboembolic complications in
patients with
atrial fibrillation ] . -
pubmed
We present in this review modern methods of prevention of
thromboembolic complications in
patients with
atrial fibrillation and give comparative description of evidence base , efficacy and safety of available techniques . -
pubmed
We describe 4 patients with
respiratory diseases where
C. - pubmed
Chronic , sometimes fatal
infections by the ascomycete
Aspergillus fumigatus and the basidiomycete
Schizophyllum commune are well established in the presence of an
anatomical pulmonary defect or in the background of
immunodeficiency . -
pubmed
Early rehabilitation in
patients operated for
breast carcinoma . -
pubmed
Its expression in the
chrysanthemum was up - regulated by salinity or
dehydration stress , but not by
abscisic acid (
ABA ) . -
pubmed
There was also limited evidence that prophylactic antibiotics reduced
bacteriuria in non - surgical
patients . -
pubmed
Interplay between autophagy and apoptosis mediated by
copper oxide nanoparticles in
human breast cancer cells
MCF7 . -
pubmed
These
CuO NPs ( ~30 nm ) induce autophagy in
human breast cancer cell line ,
MCF7 in a time- and dose - dependent manner . -
pubmed
Irrespectively of the many possible mechanisms of
HBV reactivation in patients infected with
HIV ( escape mutants selection , host
immune deficiency progression , antiretroviral - related immune reconstitution ,
glucocorticosteroids , chemotherapy ) , the message is that
HIV patients should be monitored strictly not only by serological and virological assays to recognize early
HBV reactivation , but also for drug over - exposure . -
pubmed
METHOD : A total of 99 consecutive adult
patients ( & gt;= 18 years ) with diagnosis of
somatoform disorders according to the International Classification of Diseases-10th Revision ( ICD-10 ) were evaluated for their explanatory models using the causal models section of Explanatory Model Interview Catalogue ( EMIC ) . -
pubmed
METHODS : Consecutive
patients with
ICH were enrolled as part of the Multicenter Study on
Cerebral Hemorrhage in Italy ( MUCH - Italy ) . -
pubmed
Within the subgroup of
patients taking OACs , international normalized ratio ( INR ) values were higher in those with lobar
ICH as compared to those with deep
ICH ( 2.8 + - 1.1 vs 2.2 + - 0.8 ; p = 0.011 ) . -
pubmed
The proportion of
patients with lobar
hematoma increased with increasing intensity of anticoagulation , with a ~2 - fold increased odds of lobar compared to deep
ICH ( odds 2.17 ; p = 0.03 ) in those exposed to overanticoagulation ( INR values & gt;3.0 ) . -
pubmed
The purposes of this study were to describe the effects of B1AA on survival in
septic animals and to explore for molecular mechanisms of potential treatment benefit . -
pubmed
Immunologic disease ( p = 0.0003 - 0.036 ) and cell
death / survival ( p = 0.0001 - 0.042 ) were significantly associated with improved survival in septic
mice treated with B1AA . -
pubmed
RESULTS : 80
patients with 339
thyroid nodules were included . -
pubmed
Ten
thyroid cancers (
TCs ) in ten
patients were diagnosed in histopathology . -
pubmed
Therefore , in this study , in order to understand the role of cell cycle regulators in
preeclamptic placentas we aimed to determine the spatio - temporal immunolocalizations of cell cycle regulators in
preeclamptic and normal
human term placentas . -
pubmed
In this study , we evaluated the incidence , clinical features , risk factors , and outcomes of
ES in
children and adults undergoing first - time allogeneic HCT . -
pubmed
Among 927
patients , 119 ( 13 % ) developed
ES at a median of 10 days ( interquartile range 9 to 12 ) after HCT . -
pubmed
ES
patients experienced significantly higher cumulative incidence of grade 2 to 4 acute
GVHD at day 100 ( 75 % versus 34 % , P & lt ; .001 ) and higher nonrelapse mortality at 2 years ( 38 % versus 19 % , P & lt ; .001 ) compared with non - ES
patients , resulting in lower overall survival at 2 years ( 38 % versus 54 % , P & lt ; .001 ) . -
pubmed
Despite early recognition of the
syndrome and prompt institution of
corticosteroid therapy , outcomes in
ES patients were uniformly poor . -
pubmed
METHODS : Male
Japanese subjects with or without
AGA ( n = 369 ) were included in this study . -
pubmed
We also showed that
Pkd1 ( RC / RC ) mice experience
hepatic hypertrophy that can be corrected by
pasireotide . -
pubmed
Effects of AFO use on walking in
boys with
Duchenne muscular dystrophy : a pilot study . -
pubmed
The aim of this pilot study was to describe the effects of dynamic response AFO ( DR - AFO ) use in
boys with
DMD who are ambulatory . -
pubmed
OBJECTIVE : To identify
patient factors and health care utilization patterns associated with dose escalation during the first year of long - term opioid therapy for
chronic pain . -
pubmed
MATERIAL AND METHODS : From September 2007 to August 2012 , 55
patients with large rectal
carcinoid tumors were treated by EMR - C ( 30 cases ) or ESD ( 25 cases ) . -
pubmed
Twenty four hours following reperfusion of a 2 - h
ischemic stroke ,
rats received either 0.56 - mg / kg
DETC -
MeSO or 40 - mg / kg of
taurine , either alone or in combination , subcutaneously for 4days . -
pubmed
MATERIALS AND METHODS : Twenty - one
patients suffering from irregularly formed
tracheostoma after laryngectomy followed by insertion of a speech valve were provided with a
silicone tracheostomal prosthesis . -
pubmed
Going green : using a bio - cellulose membrane for
patients with chronic non - healing
wounds . -
pubmed
METHODS : Three
patients underwent laparoscopic abdominal wall reconstruction for complex
hernias in August and September of 2015 . -
pubmed
CONCLUSION : Laparoscopic abdominal wall reconstruction with transversus abdominis release is a unique and feasible approach to complex
abdominal wall defects with the potential to reduce
pain , facilitate recovery , and decrease length of hospital stay for
patients . -
pubmed
RESULTS
Patients complained of
CLBP for 11.32 + -6.81 years on average . -
pubmed
Comparative Effects of Roux - en - Y Gastric Bypass and Sleeve Gastrectomy on
Glucose Homeostasis and Incretin Hormones in
Obese Type 2 Diabetic Patients : A One - Year Prospective Study . -
pubmed
The aim of the work was to compare the hormonal and the metabolic mechanisms involved in
weight loss and remission of
T2DM one year after Roux - en - Y gastric bypass ( RYGB ) and vertical sleeve gastrectomy ( VSG ) in morbidly obese
type 2 diabetic (
T2DM )
patients . -
pubmed
BACKGROUND : Increased free
cortisol fraction is associated with
insulin dysregulation (
ID ) in
people with
Metabolic Syndrome and
Cushing ' s Disease . -
pubmed
Free
cortisol has not been investigated in
equine endocrine disorders . -
pubmed
ANIMALS : Fifty - seven healthy
horses ; 40
horses and
ponies with
PPID ( n = 20 ) or EMS ( n = 20 ) . -
pubmed
CONCLUSIONS AND CLINICAL IMPORTANCE : Increased FCF is associated with
obesity in healthy
horses and with
ID (
hyperinsulinemia ) in
horses and
ponies with
endocrine disease . -
pubmed
Decreased plasma
cortisol - binding capacity could be a component of these
endocrine disorders in
horses . -
pubmed
One trial , with 84
participants , treated mild
sensory impairment of less than six months ' duration , and the other , with 95 participants , treated nerve function impairment of 6 to 24 months ' duration . -
pubmed
No systemic
infection with visible symptoms or accumulation of viral DNA in the upper leaves was observed in H24 challenged with another isolate ,
TYLCV - IL (
TYLCV - IL [ JR : Osaka ] ) , confirming that H24 is resistant to the IL
strain . -
pubmed
We report 2 cases of
hypothyroidism in whom the associated
haematological disturbances (
macrocytic anaemia in both cases , mild
leukopenia and
thrombo - penia in one
patient ) failed to be corrected by thyroid hormone replacement therapy . -
pubmed
These findings in
humans were consistent with the results from a
pilocarpine - induced
animal model of
chronic epilepsy . -
pubmed
Indoor
tobacco legislation is associated with fewer emergency department visits for
asthma exacerbation in children . -
pubmed
Switching to aflibercept among
patients with treatment - resistant neovascular age - related
macular degeneration : a systematic review with meta - analysis . -
pubmed
PURPOSE : To systematically review anatomical and functional outcomes subsequent to switching from
bevacizumab /
ranibizumab to aflibercept monotherapy in
patients with treatment - resistant neovascular age - related
macular degeneration (
nAMD ) . -
pubmed
These
patients had poorly responsive
chronic disease with limited potential for visual recovery . -
pubmed
The European Association for Neuro - Oncology guideline provides recommendations for the clinical care of adult
patients with
astrocytic and oligodendroglial gliomas , including
glioblastomas . -
pubmed
The recommendations are a resource for professionals involved in the management of
patients with
glioma , for patients and caregivers , and for health - care providers in Europe . -
pubmed
The aim of this study was to evaluate the prevalence of parasitological contamination ( helminthes eggs , Giardia and
Entamoeba histolytica cysts ) of
salad vegetables sold at supermarkets and street vendors in Amman and Baqa'a - Jordan . -
pubmed
cysts was 23 % , 6 % , 0 % and 0 % ; Taenia / Echinococcus eggs was 20 % , 0 % , 5 % and 0 % ;
Fasciola hepatica eggs was 13 % , 3 % , 2 % and 0 % ; and
E. - pubmed
Neuroprotective effects of
vitamin D alone or in combination with
lamotrigine against
lithium -
pilocarpine model of
status epilepticus in
rats . -
pubmed
Therefore , in the present study , the neuroprotective effects and mechanisms of
vit - D alone or in combination with
lamotrigine have been evaluated in the
lithium -
pilocarpine model of
SE in
rats . -
pubmed
A
strain of
Vibrio parahaemolyticus that emerged in 1995 caused the first known pandemic involving this species . -
pubmed
Chemopreventive effect of
artesunate in
1,2 - dimethylhydrazine - induced
rat colon
carcinogenesis . -
pubmed
Diabetes Mellitus in
Children . -
pubmed
BACKGROUND :
Patients with
kidney dysfunction are at risk of developing
ischaemic heart disease . -
pubmed
CONCLUSIONS : We report a strong association between kidney function and all - cause mortality at both early , mid- and long - term follow - up in
patients undergoing coronary angiography and intervention , with eGFR significantly associated with
MI - related mortality after one month of follow - up . -
pubmed
Further research is warranted to explore the mechanisms linking kidney function and
cardiovascular disease to improve both the short- and long - term care of these
patients . -
pubmed
Methods : A
mouse xenograft model of spontaneous
tumor metastasis was used to determine the metabolic rewiring that occurs between primary
cancers and their
metastases . -
pubmed
Metabolite analysis of
normal lung tissue in the
mouse model also revealed increased levels of these metabolites compared to tissues from normal MFP and primary MFP
tumors , indicating potential extracellular uptake by
cancer cells in lung
metastases . -
pubmed
BACKGROUND : The adoption of novel and effective
gastric cancer therapies into general clinical practice has crucial implications for
patient outcomes . -
pubmed
The current study explored trends in treatment use and overall survival in
patients with
gastric cancer in the United States . -
pubmed
METHODS :
Patients with
adenocarcinoma of the gastric cardia and noncardia were identified in the National Cancer Data Base between 2006 and 2014 . -
pubmed
RESULTS : A total of 89,098
patients with
gastric adenocarcinoma were identified . -
pubmed
In those with early - stage
cancer , endoscopic treatment increased over time in
patients with cardia and
noncardia disease . -
pubmed
In
patients with locally advanced
cardia disease , preoperative therapy use increased over time ( 2013 - 2014 [ vs 2006 - 2008 ] : odds ratio [ OR ] , 3.09 ; 95 % confidence interval [ 95 % CI ] , 2.80 - 3.41 ) . -
pubmed
In
patients with locally advanced
noncardia disease , the use of preoperative therapy also increased ( 2013 - 2014 : OR , 3.32 ; 95 % CI , 2.88 - 3.82 ) as did the use of perioperative therapy ( 2013 - 2014 : OR , 4.21 ; 95 % CI , 3.52 - 5.03 ) in lieu of postoperative treatment ( 2013 - 2014 : OR , 0.66 ; 95 % CI , 0.60 - 0.71 ) . -
pubmed
In
patients with metastatic
disease , approximately 34 % of patients with cardia and 40 % of patients with
noncardia cancer did not receive treatment . -
pubmed
CONCLUSIONS : Practice patterns for the treatment of
gastric cancer in the United States reflect the increased adoption of evidence - based therapies , including endoscopic resection of early - stage
cancer and preoperative therapy for
patients with locally advanced disease . -
pubmed
In this system , a gelatin sponge soaked with
tumor cells , cell - conditioned medium , or a compound to be tested is implanted , for 2 - 4 weeks , between the two
mouse ear skin layers . -
pubmed
Experimental Design : We produced 14 orthoxenograft transplanting
human nonseminomatous
testicular germ cell tumors (
TGCT ) in
mice , keeping the primary
tumor features in terms of genotype , phenotype , and sensitivity to
cisplatin . -
pubmed
RT - PCRs in
tumors and functional analyses in
Caenorhabditis elegans (
C. - pubmed
The virus had been discovered in 2015 as the cause of a cluster of cases of fatal
encephalitis among breeders of variegated squirrels (
Sciurus variegatoides ) in eastern Germany . -
pubmed
Phylogenetic analyses demonstrated a
spillover infection from the
Prevost ' s squirrel . -
pubmed
Drug - induced
abnormal heart rhythm known as
Torsades de Pointes (
TdP ) is a potential lethal
ventricular tachycardia found in many
patients . -
pubmed
Here , we present a single
patient who underwent bilateral microelectrode - guided stereotactic implantation of deep brain stimulating leads for the treatment of essential
tremor 52 yr following bilateral arm amputations . -
pubmed
NEW & amp ; NOTEWORTHY We had a unique opportunity to record neurons in the ventrointermediate ( Vim ) motor nucleus of thalamus in a
patient with
essential tremor , decades following bilateral forearm amputations . -
pubmed
METHODS : For Phase 1 , we will create a master list of
HIV and
STI testing sites in each city . -
pubmed
Although severe
blood coagulopathy in
horses with
acute colitis causes
multiple organ failure , which may be fatal , few studies have focused on the correlation between the fluctuations of coagulation parameters and severity of
colitis . -
pubmed
In this study , we evaluated the fluctuations of coagulation parameters in 14
Thoroughbred racehorses with
acute colitis for 5 days from the day of hospitalization and compared them between 5 survivors and 9 non - survivors . -
pubmed
PURPOSE : To identify women affected by recurrent
ovarian cancer who benefit from secondary cytoreductive surgery ( SCS ) , analyse their clinical and biological features and investigate the role of minimally invasive surgery ( MIS ) and hyperthermic intraperitoneal - based chemotherapy ( HIPEC ) in this subset of
patients . -
pubmed
CONCLUSIONS : While waiting for the final results of the ongoing randomized controlled trials , SCS seems feasible and safe in selected
patients with recurrent
ovarian cancer . -
pubmed
All 7 studies found an increased odds for at least 1
extracutaneous infection , including
endocarditis ,
meningitis ,
encephalitis ,
bone and joint infections , and
sepsis , in
AD patients . -
pubmed
CONCLUSION :
AD patients have higher odds of
extracutaneous infections . -
pubmed
One
patient was treated conservatively with an external fixator but died the next day , 2 patients received a new total hip arthroplasty and 47 underwent plate fixation of their
fracture ( one
patient was treated non - operatively because of poor medical condition ) . -
pubmed
The type of pathological response to neoadjuvant chemoradiation in
patients with locally advanced
esophageal cancer predicts overall survival ( OS).We aimed to assess early
18F - FDG positron emission tomography / computed tomography parameters in predicting the pathological response to neoadjuvant treatment . -
pubmed
The cohort included consecutive
patients with locally advanced
esophageal cancer who underwent baseline
18F - FDG positron emission tomography / computed tomography between September 2006 and February 2015 . -
pubmed
MTV at presentation is associated with the pathological response to neoadjuvant chemoradiation in
patients with locally advanced
esophageal cancer . -
pubmed
BACKGROUND :
Hepatitis C virus (
HCV ) point - of - care testing using rapid diagnostic test ( RDT ) is the solution for large - scale , feasible , fast and reliable screening of
HCV infection . -
pubmed
OBJECTIVES : The aim of this study was to evaluate the diagnostic performance of
HCV RDT for screening of
HCV infection in a real - life prison setting . -
pubmed
However , with exclusion of testing error in prison and considering
HCV RNA as the reference method for diagnosis of current
HCV infection the sensitivity reached 100 % . -
pubmed
METHODS : People living with
HIV (
PLHIV ) initiating antiretroviral therapy at 22
HIV clinics were enrolled and underwent systematic screening for
TB ( August 2012 - November 2014 ) . -
pubmed
RESULTS : Among 6041
patients enrolled ( smear arm , 1816 ; Xpert arm , 4225 ) , 256 ( 199 per 2985 and 57 per 1582 person - years of follow - up in Xpert and smear arms , respectively ; adjusted incidence rate ratio , 9.07 ; 95 % confidence interval [ CI ] : 4.70 - 17.48 ; p & lt ; 0.001 ) received
TB diagnosis and were treated . -
pubmed
Effects and cost - effectiveness of postoperative oral analgesics for additional
postoperative pain relief in
children and adolescents undergoing dental treatment : Health technology assessment including a systematic review . -
pubmed
BACKGROUND : There is an uncertainty regarding how to optimally prevent and/or reduce
pain after dental treatment on
children and adolescents . -
pubmed
Fiber dissection and brain functional mapping in 90
patients with
gliomas . -
pubmed
Second , 90
patients underwent awake craniotomy for
gliomas with direct electrical stimulations . -
pubmed
The
body weight , body composition , food intake , and energy expenditures of the
mice were measured . -
pubmed
In this report , we describe a 61 - year - old
man with isolated
sweating on the left side of his entire body . -
pubmed
The pulmonary involvement in
children with
COVID-19 was mild with a focal
GGO or consolidation . -
pubmed
INTERPRETATION : Atypical clinical findings of pregnant
women with
COVID-19 could increase the difficulty in initial identification . -
pubmed
Back From the Brink : Alterations in B and T Cell Responses Modulate Recovery of
Rainbow Trout From Chronic Immunopathological
Tetracapsuloides bryosalmonae Infection . -
pubmed
Proliferative kidney disease (
PKD ) caused by the myxozoan parasite
Tetracapsuloides bryosalmonae is one of the most serious
infectious diseases negatively impacting farmed and wild salmonids throughout Europe and North America . -
pubmed
The study also showed non - optimal treatment of
patients with
hypertension . -
pubmed
The most statin administration was observed in hypertensive
patients with
coronary artery disease ( 50.1 % ) and
myocardial infarction ( 62.7 % ) . -
pubmed
Corneal Epithelial Findings in
Patients with
Multiple Myeloma Treated with Antibody - Drug Conjugate
Belantamab Mafodotin in the Pivotal , Randomized , DREAMM-2 Study . -
pubmed
INTRODUCTION :
Patients with relapsed or refractory
multiple myeloma (
RRMM ) represent an unmet clinical need . -
pubmed
The first event resolved in most
patients ( grade > = 2 MECs and visual acuity [ each 77 % ] ,
blurred vision [ 67 % ] , and
dry eye [ 86 % ] ) , with no reports of permanent
vision loss to date . -
pubmed
CONCLUSION : Single - agent
belamaf represents a new treatment option for
patients with
RRMM . -
pubmed
OBJECTIVE : To explore the potential indicators including
patients ' characteristics , electrocardiogram ( ECG ) , echocardiography , and serological assay in predicting the major adverse cardiovascular events ( MACE ) within 1 year for
patients with low - risk
chest pain with a nomogram . -
pubmed
PATIENTS AND METHODS : The detected indicators of
patients with low - risk
chest pain were obtained as the alternative predictors for MACE . -
pubmed
A nomogram was constructed based on the multivariable Cox regression to link the independent predictors and the MACE within 1 year for
patients with low - risk
chest pain . -
pubmed
Rhythmic auditory stimulation ( RAS ) has been well researched with
stroke survivors and
individuals who have
Parkinson ' s disease , but little research exists on RAS with people who have experienced
traumatic brain injury (
TBI ) . -
pubmed
Dual - energy X - ray absorptiometry can be useful to detect abnormal bone mass and
fracture risk in this population and newer bone assessment methods are being evaluated in
children at risk for poor bone outcomes . -
pubmed
Metabolomic profiling of
IgG4 - RD patients offers an opportunity to identify novel pathophysiological targets and biomarkers . -
pubmed
CONCLUSION :
IgG4 - RD patients have a unique plasma metabolomic profile compared with healthy controls . -
pubmed
Bacillus subtilis Inhibits
Viral Hemorrhagic Septicemia Virus Infection in
Olive Flounder (
Paralichthys olivaceus ) Intestinal Epithelial Cells . -
pubmed
Bacillus subtilis is a probiotic with excellent antiviral properties , of which one of its secretions , surfactin , has been shown to inhibit
viral infections in mammals . -
pubmed
Herein , we demonstrate its ability to prevent
VHSV infection in
olive flounder (
Paralichthys olivaceus ) intestinal epithelial cells ( IECs ) and
infection in internal organs . -
pubmed
Our findings show inhibition of
VHSV infection in IECs by
B. - pubmed
Mitochondrial degeneration after organic
phosphate poisoning in
prosimian primates . -
pubmed
The degenerative reaction of mitochondria to
tricresylphosphate (
TCP )
poisoning in spinal
ganglion cells of
Slow Loris (
Nycticebus coucang coucang ) were studied with the electron microscope . -
pubmed
In neurones of
animals treated with
TCP , mitochondria display various stages of alterations which confirm mitochondrial involvement in
TCP poisoning . -
pubmed
Clinical , radiological and functional pulmonary manifestations in
patients with
leptospirosis . -
pubmed
Separate groups of
rats were sampled by
decapitation every 3 or 4 hours in two separate studies during a 24 h period consisting of 12 h light and 12 h dark . -
pubmed
The multidrug - resistant
strains most commonly isolated were
lactose - fermenting
Citrobacter freundii . -
pubmed
The overall resistance of these aquaria
strains was greater than the previously described resistance of clinical isolates of
C. - pubmed
Efficacy of training in
obese diabetic patients . -
pubmed
cells found in
dogs and
cats with
neurologic disorders , such as reactive monocytes and lymphocytes , macrophages , neutrophils and eosinophils in addition to cells of the first group , 3 . -
pubmed
Transient elevation of the intracranial pressure increases the
infarct size and perifocal
edema after subsequent
middle cerebral artery occlusion in the
rat . -
pubmed
The objective of this study was to mimic in a simple experiment the two major brain insults sustained by the
patient with a
subarachnoid hemorrhage , that is , the ictus and the subsequent delayed reduction of focal cerebral blood flow caused by
vasospasm without the interference of subarachnoid blood , to test the hypothesis that ictal events not related to the presence of blood in the subarachnoid space per se may be important for the development of
ischemic deficits and
cerebral infarction when
vasospasm develops . -
pubmed
Groups of
rats were subjected to a sudden transient elevation of the intracranial pressure to a level causing a brief period of complete global
ischemia by infusion of mock cerebrospinal fluid into the cisterna magna ( this manipulation was designed to allow survival of the
animal and recovery of consciousness ) . -
pubmed
Rats subjected to
middle cerebral artery occlusion alone and sham operation served as controls . -
pubmed
Functional digital subtraction sialography with a water soluble radiopaque agent (
verografin ) made it possible to investigate the structure and functional changes in the salivary glands of 26
patients with a minimum
injury of the glands . -
pubmed
A number of natural and synthetic
sugar analogues have been tested for their antiviral activity , using an
influenza virus strain as a model . -
pubmed
Changes that occur in
mice with experimentally induced
cryptorchidism are not identical to those seen in the
rat . -
pubmed
Teaching
patients with
ventricular dysrhythmias . -
pubmed
The
infarct size , estimated by % Defect decreased significantly in the
patients treated with V , while it remained unchanged in the
patients without it . -
pubmed
In the
patients with V , the left ventricular ejection fraction was more favourable , and exercise - induced
ischemia determined by redistribution of
201 - Tl SPECT in the chronic phase was found more frequently . -
pubmed
Guar additives did not improve the excessive postprandial glycemia found in
NIDDM patients in whom near - normal fasting plasma
glucose levels had been obtained . -
pubmed
It was previously determined that surgery plus the antibiotic
doxycycline were effective in eliminating or suppressing
Actinobacillus actinomycetemcomitans (
Aa ) , an organism strongly associated with disease in localized
juvenile periodontitis (
LJP ) . -
pubmed
Eight
patients with
LJP participated in this surgical study . -
pubmed
STUDY OBJECTIVE : To determine the prevalence of
vertebral fractures in
patients with mild asymptomatic
primary hyperparathyroidism and to ascertain whether this prevalence is increased in comparison with the rate in a retrospective control group previously studied at the same institution or with current estimates of the risk for
vertebral fractures in subjects of similar age . -
pubmed
PATIENTS : A consecutive series of
patients with mild asymptomatic
primary hyperparathyroidism diagnosed between 1 January 1976 and 31 December 1985 . -
pubmed
MEASUREMENTS AND MAIN RESULTS : The prevalence of
vertebral fractures in 174
patients ( mean age , 62 years ) with mild asymptomatic
primary hyperparathyroidism was 1.7 % ; in a subset of white women , the prevalence was 2.8 % . -
pubmed
CONCLUSIONS : The risk for
vertebral fractures is not increased in
patients with mild asymptomatic
primary hyperparathyroidism and is not a reason to recommend surgical intervention in asymptomatic
patients . -
pubmed
[ Antiparasitic activity of
Cis - Pt ( II ) pentamidine in experimental
trypanosomiasis of
sheep caused by
Trypanosoma brucei brucei ] . -
pubmed
brucei brucei ,
Cis - Pt ( II ) pentamidine was evaluated on an experimental
sheep trypanosomiasis model , standardized by the Institute of Neurological Epidemiology and Tropical Neurology of Limoges ( France ) . -
pubmed
Cis - Pt ( II ) pentamidine was able to cure infected
mice , without
relapse , after a single subcutaneous injection of 12.5 mg.kg-1
body weight . -
pubmed
In
sheep trypanosomiasis , the same treatment was used successfully during the first stage of
infection . -
pubmed
Rabies was confirmed in
dogs that died by
mouse inoculation and subsequent examination of
mouse brains by fluorescent antibody technique to detect
rabies antigen . -
pubmed
To evaluate this test further , a
dog was infected by
rabies virus , and serial serum and CSF specimens were collected until the time of
death . -
pubmed
Clonazepam , a high - potency
benzodiazepine marketed for the treatment of minor motor
epilepsy , was used to treat 50
patients with
panic disorder ( N = 22 ) or
agoraphobia with
panic attacks ( N = 28 ) . -
pubmed
Staphylococcosis in a commercial
rabbitry . -
pubmed
[ The effect of 2 %
calcium citrate on the incidence of
caries in
rats ] . -
pubmed
Pathogenesis of
osteopetrosis in
chickens . -
pubmed
Spontaneous disappearance of tumorigenicity in a
polyoma virus - induced
neoplasm carried in vitro . -
pubmed
[ The mineral feeding in
sheep herds with clinical cases of
hypocalcemia ] . -
pubmed
Five
patients with
ARN were seen . -
pubmed
Biopsy of one lesion yielded
herpes simplex virus (
HSV ) in culture . -
pubmed
Twenty - five upper extremities were operated upon in 24
patients because of
arterial occlusive disease . -
pubmed
Characterization of the peptide and sensory
neurotoxic effects of
capsaicin in the
guinea pig . -
pubmed
The results indicate that in the
guinea pig capsaicin is potent at producing a unique , long - lasting
syndrome of
peripheral sensory deficits that may result from an effect of the agent on SP - containing primary afferent neurons . -
pubmed
Study of kinetics of epithelial cell populations in normal tissues of the
rat 's intestines and in
carcinogenesis . -
pubmed
To compare the accuracy of 3DE with standard 2DE algorithms for quantitating LV volume , 28 excised
canine ventricles of known volume and varying shapes ( 15 symmetric and 13
aneurysmal ) and 10 instrumented
dogs prepared so that instantaneous ventricular volume could be measured were examined by 2DE ( bullet and biplane Simpson 's formulas ) and again by 3DE . -
pubmed
Antiarrhythmic and electrophysiologic effects of
ibutilide in a chronic
canine model of
atrial flutter . -
pubmed
We studied the effects of orally administered
ibutilide , a class III antiarrhythmic agent , in a model of reentrant
atrial flutter in conscious
dogs . -
pubmed
After baseline determination of atrial effective refractory period ( AERP ) and demonstration of reproducible induction of
atrial flutter by rapid atrial pacing , 8
dogs received either placebo or one of six doses of
ibutilide ranging from 0.1 to 5 mg / kg . -
pubmed
INTRODUCTION : The purpose of the study was to evaluate the effect of pregnancy and childbirth on the longterm prognosis for
women with
multiple sclerosis (
MS ) . -
pubmed
METHOD AND MATERIAL : A cohort of 39
women with definite
MS were identified on 1.1.1986 using a reproducible selection method . -
pubmed
OBJECTIVE : To present the CT and MR findings of three
patients with giant
intracranial aneurysms (
GIAs ) , each of which eroded the skull base and had an extracranial mass component . -
pubmed
MATERIALS AND METHODS : In the past year the imaging studies of three
patients with these unusual
GIAs were collected at our institutions . -
pubmed
Polymyxin B and an antiserum against an Re mutant
Salmonella typhimurium were evaluated for protective effect in an equine model
endotoxemia . -
pubmed
Reduced effect of inhaled
beta 2 - adrenergic agonists on lung mucociliary clearance in
patients with
cystic fibrosis . -
pubmed
Thus , we questioned whether the
beta 2 - adrenergic agonist ,
terbutaline , would improve mucociliary clearance in
patients with
CF as it does in healthy
subjects . -
pubmed
PATIENTS : Ten young
patients with
CF were studied ; three were heterozygous for deletion of the
phenylalanine at position 508 ( delta F508 ) , and seven were delta F508 homozygous . -
pubmed
CONCLUSIONS : We conclude that 1 mg of
terbutaline did not improve mucociliary clearance significantly in the
patients with
CF . -
pubmed
Histopathologic and ultrastructural findings of
photocoagulation lesions produced by transpupillary diode laser in the
rabbit retina . -
pubmed
81
patients were suffering from
hematologic malignancies and severe
aplastic anemia and six
patients had advanced
solid tumours /
sarcoma . -
pubmed
Probability of survival for
patients transplanted in the first chronic phase of
chronic myelogenous leukemia (
CML ) was 85 % , whereas the disease free survival ( DFS ) for
patients transplanted in accelerated phase or
blast crisis was only 40 % . -
pubmed
All
patients transplanted for
non - Hodgkin ' s lymphoma (
NHL ) or
Hodgkin ' s disease had refractory or advanced disease . -
pubmed
Probability of survival for
lymphoma patients was 60 % . -
pubmed
Results were compared with 44 historical control
patients treated with
CY ( 120 mg / kg ) and
TBI . -
pubmed
RESULTS : The 3 - year actuarial disease - free survival ( DFS ) rate was similar for the BU /
CY /
TBI group and the CY /
TBI group ( 23 % v 30 % , P = .6 ) , but there were trends toward lower
relapse rates ( 28 % v 54 % , P = .27 ) and higher nonrelapse mortality rates ( 68 % v 36 % , P = .12 ) among the current
patients compared with historical controls . -
pubmed
CONCLUSION :
Patients with advanced morphology
myelodysplasia tolerated the intensified BU /
CY /
TBI preparative regimen and reduced posttransplant immunosuppression poorly . -
pubmed
Predicting
patient outcome in
acute renal failure has become increasingly important as technology advances and ethical questions arise concerning life supporting therapies . -
pubmed
STUDY SELECTION : English - language articles that discussed the role of medications in the treatment of
human obesity , and studies that evaluated their safety and efficacy for a minimum of 24 weeks . -
pubmed
Until more data are available , pharmacotherapy can not be recommended for routine use in
obese individuals , although it may be helpful in carefully selected
patients . -
pubmed
[ Protein and RNA biosynthesis in the nuclei of the thymus cells of
piglets with
antenatal hypotrophy ] . -
pubmed
Differential serological diagnosis of
HTLV - I and
HTLV - II infection by external membrane protein peptide - based enzyme immunoassays . -
pubmed
BACKGROUND : HTLV antibody screening assays detect both antibodies to the etiological agent of
adult T - cell leukemia and
tropical spastic paraparesis HTLV - I and to the less pathogenic
HTLV - II . -
pubmed
The peptide EIA with the best performance was further used to differentiate between
HTLV - I and
HTLV - II antibodies in 807 samples from 18 countries in four continents and to provide ratios between the two
infections . -
pubmed
The sensitization phase of
contact hypersensitivity induced by the
hapten ,
dinitrofluorobenzene (
DNFB ) in the
mouse was used as a model of T lymphocyte trafficking in response to antigenic stimulation . -
pubmed
Cognitive performances are usually lower in
patients with
arterial hypertension . -
pubmed
A longitudinal study revealed that
patients with
AD aged 79 - 85 are more likely to have had higher values of blood pressure 10 to 15 years earlier , and they usually have a spontaneous decline of blood pressure beginning 1 or 2 years before the onset of
AD . -
pubmed
[ Effects of chronic
hypoxia on the expression of oncogene jun fos and myb mRNA in
rat lung ] . -
pubmed
This paper is to investigate the expression of oncogene jun fos and myb mRNA in the lung of
rats exposed to chronic
hypoxia . -
pubmed
The results showed that ( 1 ) there was a slight expression of jun mRNA but not fos and myb mRNA in the control normoxic
rats ' lung ; ( 2 ) it was found that a less expression of jun mRNA in lung after 1 week
hypoxia , but after 2 week
hypoxia jun mRNA elevated again and significantly increased after 3 week
hypoxia as compared with that in normoxia ; ( 3 ) the oncogene myb mRNA expression showed significant increase in 1 and 2 week
hypoxia and returned to normal status in 3 week
hypoxia ; ( 4 ) after 1 to 3 week
hypoxia , a significant increased expression of fos mRNA was found as compared with that in normoxia . -
pubmed
RESULTS : The proportion of 12 - year - old
children with no experience of
dentine caries was 47 % and 35 % were completely free from all
caries . -
pubmed
While the outcome for
patients with advanced
non - small cell lung carcinoma is still poor , new agents are being developed rapidly and offer the hope of improved survival . -
pubmed
The median concentration of
dioxin in fathers in this study is similar to doses that induce
epididymal impairments in
rats and is about 20 times the estimated average concentration of
TCDD currently found in
human beings in industrialised countries . -
pubmed
A-60 - year - old
man with medically intractable left - sided maxillary division
trigeminal neuralgia had severe
cardiac disease , was dependent on an internal defibrillator and could not undergo magnetic resonance imaging . -
pubmed
The
patient was
pain free 2 months after GKS . -
pubmed
Foam cell lesions were the only type of lesion in 12 of the aortas from transgenic
animals , while five
animals had developed
fibrofatty lesions . -
pubmed
Neutrophilic eccrine hidradenitis unassociated with chemotherapy in a
patient with
acute myelogenous leukemia . -
pubmed
SAMPLE POPULATION : Twenty limbs ( 10 limb pairs ) from 5
equine cadavers . -
pubmed
In general ,
HIV transmission in host - migrant or host - forced - migrant interactions depends on the maturity of the HIV epidemic in both the host and the migrant population , the relative seroprevalence of
HIV in the host and the migrant population , the prevalence of other
sexually transmitted infections (
STIs ) that may facilitate transmission , and the level of sexual interaction between the two communities . -
pubmed
In complex emergencies , additional factors such as sexual interaction between forced - migrant populations and the military ; sexual violence ; increasing commercial sex work ;
psychological trauma ; and disruption of preventive and curative health services may increase the risk for
HIV transmission . -
pubmed
Atypical antipsychotics have revolutionized the treatment of
schizophrenia , becoming the treatment of choice for
patients not only during their first episode , but also throughout their life course . -
pubmed
Atypical agents may be particularly helpful for elderly , child , or adolescent
patients who are especially susceptible to the side effects of medications and whose risk of
tardive dyskinesia is high but further controlled studies are necessary . -
pubmed
Intravenous / oral sequential therapy in
patients hospitalised with community - acquired
pneumonia : which patients , when and what agents ? -
pubmed
A new trend in antibacterial therapy is sequential therapy ( intravenous / oral ) in hospitalised
patients with moderate to severe
infections . -
pubmed
CAP requires prompt and effective antibacterial treatment and conventional therapy for
patients hospitalised with
CAP has typically been parenteral antibacterial therapy for 7 to 10 days . -
pubmed
Today a large number of clinical trials in
patients with
CAP have been undertaken and sequential therapy with appropriate antibacterials used in suitable patients has been proven as a treatment option . -
pubmed
In the studies presented here we provide data on our lead preclinical compound and compare its antivascular and antitumour activity to that of
CA4P in the
murine breast adenocarcinoma CaNT . -
pubmed
pylori eradication can be considered one of the methods to prevent
gastric cancer in patients with
H. - pubmed
22 - kHz ultrasonic vocalization in
rats as an index of
anxiety but not fear : behavioral and pharmacological modulation of affective state . -
pubmed
Ultrasonic vocalization ( USV ) was found useful for differentiating fear and
anxiety in
rats . -
pubmed
METHODS : Seventeen hydrogel lenses were explanted from 17 different
patients owing to
decreased visual acuity or quality of vision an average of 29 months after uneventful phacoemulsification and IOL implantation and associated with a granular - appearing opacification superficially within the optic . -
pubmed
[ CLINICO - BIOCHEMICAL COMPARATIVE STUDIES IN THE DIAGNOSIS OF EARLY PHASES OF DEVELOPMENT OF
HEPATIC DYSTROPHY IN
PATIENTS WITH
BOTKIN ' S HEPATITIS ] . -
pubmed
vivax infections , one in buffalo and another in a
cow , PCR detected
infections in 34.8 % buffaloes , 44.7 % bovines and 37.3 %
sheep . -
pubmed
Trypanozoon primers detected 41.8 %
infections in buffaloes and 8.1 % in
cattle . -
pubmed
PCR revealed 6.9 % mixed
infections in buffaloes and 5.3 % in
cattle . -
pubmed
Both
patients were treated by clipping of the
aneurysm , and the signs of
oculomotor nerve paresis gradually resolved . -
pubmed
A pattern of
pupil - sparing paresis was observed during the early recovery stage in both
patients . -
pubmed
We propose that CSF analysis may become part of the diagnostic work - up of
patients with
parkinsonian syndromes . -
pubmed
Some old
mice fight
parasitic infection better than young
mice do . -
pubmed
METHODS : Thirty - seven
patients with
short bowel syndrome received bowel rehabilitation therapy for 4 weeks . -
pubmed
Thirty - four
patients were treated within 2 years after
short bowel syndrome . -
pubmed
RESULTS : All
patients completed the treatment ; there were no
deaths caused by
malnutrition . -
pubmed
vivax /
Plasmodium malariae mixed
infection ( 3.0 % ) . -
pubmed
In conclusion , increases in
malaria cases , mostly due to
P. - pubmed
In an in vitro analysis of 41 individual
patient - derived primary
tumor samples ,
B - cell chronic lymphocytic leukemia (
B - CLL ) and
marginal zone lymphoma showed the strongest activation upon stimulation with
CpG oligodeoxynucleotides . -
pubmed
Focusing clinical studies on
patients with highly CpG oligodeoxynucleotide - sensitive
B - cell malignancies may improve the clinical outcome of such trials . -
pubmed
Advances in
allergic skin disease ,
anaphylaxis , and
hypersensitivity reactions to foods , drugs , and
insects . -
pubmed
This review highlights some of the research advances in
allergic skin disease ,
anaphylaxis , and
hypersensitivity reactions to foods , drugs , and
insects that were reported primarily in the Journal in 2004 . -
pubmed
Polioencephalomalacia in
cattle in New Zealand fed
chou moellier (
Brassica oleracea ) . -
pubmed
Polioencephalomalacia was diagnosed clinically in 26 heifers from a herd of 99
grazing chou moellier (
Brassica oleracea ) . -
pubmed
A positive
patient history or family history of
allergy were documented . -
pubmed
In this study we determined whether a similar change takes place in
patients with
bipolar disorder with and without a history of
psychosis . -
pubmed
BACKGROUND : Left atrium ( LA ) in
patients with
hypertrophic cardiomyopathy (
HC ) has been known to have an increased size and decreased contractile function . -
pubmed
METHODS : We performed real - time 3D echocardiography on 26
patients with
HC and on 15 control subjects . -
pubmed
Patients with
HC showed decreased LV early diastolic dV / dt compared with control subjects ( 0.10 + /- 0.05 vs 0.14 + /- 0.04 mL / ms , P & lt ; .05 ) . -
pubmed
In
rats and
mice , the
middle cerebral artery occlusion (
MCAO ) model was used to represent
cerebrovascular stroke , while in
gerbils the two - vessel occlusion model , representing global
ischemia , was used . -
pubmed
In the second half of this review , we present data on neuroprotection by
estrogen and
progesterone in
animal model of
epilepsy followed by exploration into ovarian
steroid effects on
neuronal damage in models of
multiple sclerosis and
traumatic brain injury . -
pubmed
Ongoing studies are being performed to determine if the addition of
panitumumab to first - line standard treatment for metastatic
colorectal cancer will improve the progression - free and overall survival of these
patients . -
pubmed
This study examined seasonal changes in
body weight , hibernation period , and body temperature of the
Japanese badger (
Meles meles anakuma ) from 1997 to 2001 . -
pubmed
A-56 - yr - old Malay
man was diagnosed to have
adenocarcinoma of the right colon [ Dukes B ] for which a right hemicolectomy was performed , followed by radiotherapy and chemotherapy . -
pubmed
Animal studies demonstrated that
females are more susceptible than
males to
benzo [ a ] pyrene (
BaP)-induced
toxicities , including
lung carcinogenesis . -
pubmed
METHODS : A total of 356
patients with confirmed diagnosis of active
RA from 9 clinical centers were randomly assigned to the TCM group ( 184 cases ) and the
WM group ( 172 cases ) . -
pubmed
RESULTS : The platelet count was positively correlated to the X- ray grading of
joint damage , namely ,
patients with a more severe
joint damage often presented a higher platelet count . -
pubmed
CONCLUSION : Platelet count is closely correlated to the efficacy of drug therapy , therefore , it may be taken as an important index for judging the curative effect of therapeutic approach in treating
RA patients . -
pubmed
Experimental
diabetes treated with
Achillea santolina : effect on pancreatic oxidative parameters . -
pubmed
In the present study , we examined possible protective effect of
Achillea santolina L. (
Compositae ) against
pancreatic damage in
streptozotocin (
STZ)-treated
diabetic rats . -
pubmed
ASE ( 0.1g / kgday ) was orally administered to a group of
diabetic rats for 30 consecutive days . -
pubmed
A 38 - year - old
woman presented after 2 weeks with penetrating
craniocerebral injury from a six inch nail . -
pubmed
AN UPDATE ON
CAT SCRATCH DISEASE :
Cat scratch disease is an uncommon and
infectious disease of
man characterized by regional
lymphadenopathy following a scratch or a
bite from a
cat or other inoculation
wounds . -
pubmed
Preoperative three - dimensional computed tomographic scans were used to acquire the stereolithographic biomodeling of the
patient for assessing the amount of
bone defect and precise planning of the surgery . -
pubmed
It shows bactericidal activity against forms of
Staphylococcus aureus (
phagolysosomal infection ) with different resistance phenotypes [
methicillin - resistant
S. - pubmed
We assessed the status of
dopamine nerve terminals in
patients treated with
dopamine receptor blocking agents ( DRBAs ) who had developed drug - induced
parkinsonism (
DIP ) . -
pubmed
We performed
[ ( 123 ) I ] FP - CIT SPET in 32 consecutive
patients who were on DRBAs for at least 6 months and developed
extrapyramidal signs . -
pubmed
Conversely , symmetry of
parkinsonian signs and presence
bucco - linguo - masticatory dyskinesias were more frequent in
individuals with normal tracer binding . -
pubmed
Lutzomyia longipalpis ( Diptera , Psychodidae , Phlebotominae ) and urbanization of
visceral leishmaniasis in Brazil . -
pubmed
The article discusses habits related to the vectorial competence of
Lutzomyia longipalpis , along with evidence confirming the importance of this sand fly species in the epidemiological chain of
visceral leishmaniasis in Brazil . -
pubmed
A new epidemiological profile for
visceral leishmaniasis is also postulated , associated with domestic environments and the role of
Lu . - pubmed
METHODS : We asked whether the correlation previously established in
rodents extends to the best
nonhuman primate model of
PD , the
1 - methyl-4 - phenyl-1,2,3,6 - tetrahydropyridine (
MPTP)-lesioned
macaque . -
pubmed
Inter - rater reliability of three standardized functional tests in
patients with
low back pain . -
pubmed
BACKGROUND : Of all
patients with
low back pain , 85 % are diagnosed as " non - specific
lumbar pain " . -
pubmed
The aim of this present study was to therefore standardize and examine the inter - rater reliability of three functional tests of muscular functional coordination of the lumbar spine in
patients with
low back pain . -
pubmed
A 67 - year - old
man with
celiac disease developed recurrent
diarrhea , profound
weakness and
weight loss , with evidence of marked protein depletion . -
pubmed
[ Genomic damage , adaptive response induction in blood lymphocytes at the
prostate cancer patients . -
pubmed
It was shown that in oncological
patients the DSB level and the frequency of cells with
MN have been increased . -
pubmed
We can suppose that prognosis of the treatment efficiency of the
prostate cancer patients with the pronounced adaptive response in blood lymphocytes will be worse . -
pubmed
We aimed to investigate whether PCI had different clinical outcomes from ACI in Chinese
patients with
ischemic stroke . -
pubmed
METHODS : Data on
ischemic stroke patients with ACI or PCI were collected including demographics , risk factors and 1 - month , 3 - month , and 1 - year case fatality and disability ( defined as modified Rankin Scale 3 - 5 ) . -
pubmed
The adjusted hazard ratio of
death for PCI was 0.52 at 1 month ( 95 % CI 0.29 - 0.94 ) and 0.52 at 3 months ( 95 % CI 0.31 - 0.85 ) , and the adjusted odds of disability in
patients with PCI was 0.53 at 1 year ( 95 % CI 0.35 - 0.81 ) . -
pubmed
Knowledge on the biodistribution and potential shedding of AAV2 is crucial to evaluate the risks of
infection with the viral vector for the
patient and the environment . -
pubmed
Individual patient data from four randomised trials in
fibromyalgia ( 2575
patients ) lasting 8 - 14weeks were used to calculate percentage
pain reduction for each completing
patient ( 1858 ) , divided into one of five groups according to
pain reduction , irrespective of treatment : substantial benefit - 50 %
pain reduction ; moderate - 30 % to & lt;50 % ; minimal - 15 % to & lt;30 % ; marginal - 0 % to & lt;15 % ; worse - & lt;0 % ( increased
pain intensity ) . -
pubmed
Infection with
Chlamydia pneumoniae ( Cp ) accounts for around 10 % of community acquired
bacterial pneumonia and has been associated with other chronic inflammatory conditions . -
pubmed
We describe a C57 / Bl6
murine model of
Cp lung infection characterized by a dose - dependent , resolving
neutrophilia followed by lymphocytic infiltration of the lungs . -
pubmed
DENTAL caries in the
rhesus monkey . -
pubmed
This study reports on the molecular systems biology of
gastrointestinal nematode ( GIN ) infection and potential biomarkers for
GIN resistance in
sheep . -
pubmed
These results provide specific gene targets for therapeutic interventions and provide insights into
GIN infections in
sheep which may be used to infer the same in related host species . -
pubmed
Endotracheal nebulization of
N - acetylcysteine increases airway resistance in
cats with experimental
asthma . -
pubmed
We hypothesized that in
cats with experimental
asthma , aerosol delivery of
NAC ( 400 mg cumulative dose ) via an endotracheal tube would increase airflow limitation as measured by ventilator - acquired mechanics . -
pubmed
After endotracheal drug delivery , airway resistance and inspiratory plateau pressure ( Pplat ) measurements were obtained in six mechanically ventilated
asthmatic cats . -
pubmed
All
cats exhibited at least one adverse effect : excessive airway secretions ( n=3 ) , spontaneous
cough ( n=2 ) , unilateral
strabismus ( n=1 ) and
post - anesthetic death ( n=1 ) . -
pubmed
No adverse reactions were noted with saline aerosol ;
cough was noted in one
cat with
methacholine challenge . -
pubmed
Further studies must be performed to evaluate if it is an effective mucolytic and/or antioxidant in
cats and to determine if bronchodilator pre - treatment will negate
NAC - induced
bronchoconstriction . -
pubmed
End - stage renal disease :
sudden cardiac death : stratifying risk in dialysis
patients . -
pubmed
Furthermore , variability in enterocyte
injury was observed among hyphal - producing
C. - pubmed
A
mouse model of term
chorioamnionitis : unraveling causes of adverse neurological outcomes . -
pubmed
A
mouse model of
intrauterine inflammation at term was utilized by injecting
lipopolysaccharide ( LPS ) , or normal saline into uterine horn . -
pubmed
THE PURPOSE OF THE RESEARCH : This study was designed to assess knowledge and attitude with respect to
epilepsy among secondary school
students (
epileptic and none ) in Assiut city , Egypt . -
pubmed
Only 7.1 % of
epileptic students and 8.5 % of non -
epileptic students thought that the
epilepsy is a
brain disease . -
pubmed
MATERIAL AND METHOD : The authors reviewed the data of dose measurement record from 53
patients ' treatment files to report the uniformity of absorbed in vivo dose distribution throughout the whole body from
TBI with semiconductor detectors and ionization chamber with the accepted homogeneity within + /- 10 % of the prescribed dose . -
pubmed
In - vitro studies demonstrated that 2 and 4 were active against
HeLa (
human cervical cancer ) ,
A375 (
human malignant melanoma ) ,
HepG2 (
human hepatocellular carcinoma ) ,
MCF-7 (
human breast cancer ) ,
A549 (
human nonsmall cell lung cancer ) ,
K562 (
human chronic myeloid leukemia ) , and
K562 /
ADR (
human adriamycin - resistant
K562 ) cell lines with IC(50 ) values in the range of 3.2 - 64.1 muM. -
pubmed
Vibrio parahaemolyticus is a marine bacterium , responsible for
gastroenteritis in
humans . -
pubmed
Atypical
strains of
V. - pubmed
Surgical intervention in
vascular trauma in
children . -
pubmed
Arterial injury in
children presents a challenge to the surgeon and may have long - term implications . -
pubmed
METHODS :
Patients ( & lt;13 years ) with
vascular injury requiring surgical intervention were retrospectively reviewed from a
trauma database of 446
trauma patients admitted to the Tygerberg Children 's Hospital . -
pubmed
RESULTS : We reviewed a total of 20
children where surgical intervention for
vascular trauma was required . -
pubmed
The first
Plasmodium vivax relapses of life are usually genetically homologous . -
pubmed
Distinctive features between community - acquired
pneumonia (
CAP ) due to
Chlamydophila psittaci and
CAP due to
Legionella pneumophila admitted to the intensive care unit ( ICU ) . -
pubmed
The spectrum of community - acquired
pneumonia (
CAP ) due to
Chlamydophila psittaci ranges from mild , self - limited
CAP , to acute
respiratory failure . -
pubmed
We performed a retrospective study of 13 consecutive patients with
CAP due to
C. - pubmed
Human erythrocytes and
neuroblastoma cells are in vitro affected by
sodium orthovanadate . -
pubmed
This report presents evidence in order that
orthovanadate interacted with red cell membranes as follows : a ) in scanning electron microscopy ( SEM ) studies it was observed that morphological changes on
human erythrocytes were induced ; b ) fluorescence spectroscopy experiments in isolated unsealed
human erythrocyte membranes ( IUM ) showed that an increase in the molecular dynamics and/or water content at the shallow depth of the lipids
glycerol backbone at concentrations as low as 50muM was produced ; c ) X - ray diffraction studies showed that
orthovanadate 0.25 - 1mM range induced increasing structural perturbation to
DMPE ; d ) somewhat similar effects were observed by differential scanning calorimetry ( DSC ) with the exception of the fact that
DMPC pretransition was shown to be affected ; and e ) fluorescence spectroscopy experiments performed in
DMPC large unilamellar vesicles ( LUV ) showed that at very low concentrations induced changes in
DPH fluorescence anisotropy at 18 C. Additional experiments were performed in
mice cholinergic
neuroblastoma SN56 cells ; a statistically significant decrease of cell viability was observed on
orthovanadate in low or moderate concentrations . -
pubmed
Recent discovery of
Taxol a
diterpenoid obtained form
Taxus species has opened new vistas in the treatment of
cancer and can be considered a major break through . -
pubmed
Patients with intense
carbon black exposure following industrial accidents will need frequent evaluation to manage any related
respiratory tract injury . -
pubmed
Imipramine protects
mouse hippocampus against
tunicamycin - induced cell
death . -
pubmed
This study retrospectively analyzes the results of arthrolysis and hinged external fixation performed on 15
patients suffering from
ankylosed elbows . -
pubmed
The in vitro
cytotoxicities of both complexes were preliminarily evaluated and the
cytotoxicity of complex 1 against the
human lung cancer cells (
H1299 ) is similar to
oxaliplatin , but higher than
transplatin and
carboplatin . -
pubmed
HSV-1 infection induced cell death as early as 6 h after
infection through the
necrotic pathway and required de novo protein synthesis in
L929 cells . -
pubmed
Novel
mouse model of chronic inflammatory and
overactive bladder by a single intravesical injection of
hydrogen peroxide . -
pubmed
There is so far no generally accepted
animal model of chronic
cystitis by which potential therapies can be evaluated . -
pubmed
In this study , we aimed to establish a new
mouse model of
cystitis based on the proinflammatory effects of reactive
oxygen species . -
pubmed
Management of elderly
patients with
primary central nervous system lymphoma . -
pubmed
Elderly patients , or those over the age of 60 years , represent an important subgroup and account for over half of
PCNSL patients . -
pubmed
However , chemotherapy is associated with systemic
toxicities , such as
myelosuppression , to which the older
patient is more vulnerable . -
pubmed
Radiotherapy is also effective but is limited by significant delayed
neurotoxicity , especially in older
patients . -
pubmed
Most studies support the use of chemotherapy - only treatments for elderly
patients given the high risks of
neurotoxicity associated with radiotherapy . -
pubmed
Acoustic emission based monitoring of the microdamage evolution during
fatigue of
human cortical bone . -
pubmed
The current study aims to assess the time history of the occurrence of AE events during
fatigue loading of
human tibial cortical bone and to determine the associations between AE variables ( energy content of waves , number of AE waveforms , etc . ) -
pubmed
Fatigue test specimens were prepared from the distal diaphysis of
human tibial cortical bone ( N = 32 , 22 to 52 years old , male and female ) . -
pubmed
[ Dietary patterns in
patients with
attention deficit hyperactivity disorder ] . -
pubmed
OBJECTIVE : To evaluate the dietary patterns in a group of
patients diagnosed with
attention deficit hyperactivity disorder (
ADHD ) and under treatment with extended - release
methylphenidate (
MPH - ER ) . -
pubmed
MATERIAL AND METHODS : A nutrition survey ( food intake recall for three consecutive days ) was carried out on 100
patients diagnosed with
ADHD and under treatment with
MPH - ER , and in 150 healthy
children ( control group ) . -
pubmed
The consumption of
cereals , meat ,
pulses and
fruits in the control group was significantly higher ( P & lt ; .05 ) than in
ADHD group . -
pubmed
RESULTS : Overall , 301
patients had
OPN and 149 LPN . -
pubmed
MATERIALS AND METHOD : The study consisted a group of 223 randomly selected
asthma patients with varying degrees of
asthma control . -
pubmed
The incidence and patterns of hardware failure after separation surgery in
patients with
spinal metastatic tumors . -
pubmed
BACKGROUND CONTEXT :
Spine metastases occur frequently in
patients with
cancer . -
pubmed
PURPOSE : The purpose of this study was to determine the incidence of symptomatic hardware failure and the associated risk factors in
patients with
metastatic epidural spinal cord compression (
MESCC ) . -
pubmed
PATIENT SAMPLE : The current series analyzes a cohort of 318
patients who underwent separation surgery , which involves single - stage posterolateral decompression and posterior segmental instrumentation for
MESCC . -
pubmed
RESULTS : Of the 318
patients , nine ( 2.8 % ) exhibited
signs and symptoms of hardware failure and required revision of the instrumentation . -
pubmed
CONCLUSIONS : The incidence of hardware failure is low in
patients with
MESCC who undergo posterolateral decompression and posterior screw - rod instrumentation . -
pubmed
NOD.IFNAR1(-/- )
mice developed
insulitis and
diabetes at a similar rate to NOD controls . -
pubmed
Successful use of
eculizumab in an 86 - year - old
patient with
paroxysmal nocturnal hemoglobinuria in Japan . -
pubmed
Eculizumab was used to treat an 86 - year - old male
patient with
paroxysmal nocturnal hemoglobinuria , the oldest reported case in Japan . -
pubmed
As observed in younger
patients , this drug rapidly suppressed
hemolysis in the present
patient , which allowed weaning from blood transfusion . -
pubmed
Despite the
patient 's advanced age , the inhibition of complement activity caused by this drug did not result in
infection , indicating that it is safe to use in elderly
patients . -
pubmed
We report an extremely rare case of
GIST of the anal canal in 60 - years - old
man with history of irregular bowel habits with dark colored stool mixed with blood and
constipation from 6 month . -
pubmed
The Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention recommends that
human papillomavirus (
HPV ) vaccination routinely be targeted to females and males aged 11 years or 12 years as part of the adolescent immunization platform to help reduce the incidence of
anogenital cancers and
genital warts associated with
HPV infection . -
pubmed
Obstetrician - gynecologists should advise patients and parents that
HPV vaccines are most effective in preventing
genital cancers when administered before the onset of sexual activity . -
pubmed
OBJECTIVE : To investigate self - reported
upper gastric symptoms experienced by
patients with
chronic kidney disease (
CKD ) and compare associations between uraemic symptoms and saliva composition . -
pubmed
METHODS : In a cross - sectional observational study , 30
patients with Stages 4 and 5
CKD were selected from a tertiary hospital renal outpatient clinic . -
pubmed
CONCLUSION : Altered saliva composition in
patients with Stages 4 and 5
CKD may be associated with
uraemic upper GI symptoms . -
pubmed
To date , there is a paucity of relevant model systems to critically evaluate how the signature
genetic abnormalities detected in
human ATC contribute to disease pathogenesis . -
pubmed
IMPLICATIONS : This genetically relevant
mouse model of ATC will be an invaluable platform for preclinical testing of pathway - targeted therapies for the prevention and treatment of
thyroid carcinoma . -
pubmed
A 74 - year - old
man with
intermittent claudication had undergone balloon - expandable stenting for the left
CIA . -
pubmed
Cytological smears were taken from the lesional site of
leukoplakia patients and buccal mucosa of controls . -
pubmed
Oxidative stress - mediated
cytotoxicity and metabolism of
T-2 toxin and
deoxynivalenol in animals and
humans : an update . -
pubmed
Conclusion We have shown that
hypoplastic PNH patients can be allografted safely using RIST and that the long - term results are adequate , the cost - benefit ratio of this treatment being reasonable . -
pubmed
687 baseline and 30 months follow - up MRIs of the knees of 348
overweight and obese middle - aged
women , free of
OA at baseline , were scored using the MOAKS . -
pubmed
The
subjects were evaluated for clinical and radiological outcome who were manifested by
back pain alone ( n = 4 ) or
back pain with
leg pain ( n = 19 ) associated with a primary diagnosis of
degenerative spondylolisthesis ,
massive disc herniation ,
lumbar stenosis ,
recurrent disc herniation or
degenerative disc disease . -
pubmed
Three
patients had persistent
back pain , 4
patients had residual
numbness or
radiculopathy . -
pubmed
The
bowhead whale transcriptome is a valuable resource for the study of this remarkable animal , including the evolution of longevity and its important correlates such as resistance to
cancer and other diseases . -
pubmed
We assume that in order to increase farmers ' motivation to have their animals immunized against
BTV-8 , ( 1 ) the vaccination needs to be subsidized , ( 2 ) combined vaccines with several different BT serotypes or even other
diseases should be available and ( 3 ) farmers need to be better informed about the safety and benefit of vaccination . -
pubmed
OBJECTIVES : Prognosis for
patients with locally advanced
esophagogastric adenocarcinoma (
EAC ) is poor with surgery alone , and adjuvant therapy after open esophagectomy is frequently not tolerated . -
pubmed
Recurrence patterns were similar between groups and 65 % of
patients with IIb or greater pathologic stage received adjuvant therapy . -
pubmed
Our data suggest that primary MIE in
patients with resectable
EAC may be a reasonable approach , improving stage - based prognostication and potentially minimizing overtreatment in
patients with early stage
disease through accurate stage assignments . -
pubmed
The squid ink polysaccharides protect tight junctions and adherens junctions from
chemotherapeutic injury in the small intestinal epithelium of
mice . -
pubmed
Comparative study of renal protective effects of
allopurinol and
N - acetyl - cysteine on contrast induced
nephropathy in
patients undergoing cardiac catheterization . -
pubmed
MATERIALS AND METHODS : This is a study of 500
patients undergoing angiography and coronary revascularisation in
patients showing significant
coronary block . -
pubmed
RESULTS :
CIN occurred in 56 of 500 the
patients ( 10.6 % ) who underwent angiography and 49 of 275
patients ( 17.8 % ) who underwent angioplasty . -
pubmed
In the
omnipaque group
CIN occurred in 16/40 , 8/40 , nil/45 in
patients receiving SH ,
NAC plus
SH and SH plus ALLP respectively . -
pubmed
CONCLUSION : Prophylactic oral administration of
allopurinol ( 300 mg / day ) along with hydration is better than
n - acetylcysteine and saline hydration alone for protection against
CIN in
patients undergoing coronary procedures . -
pubmed
This study aims to investigate whether attention and spatiotemporal integration deficits are dissociated in
patients with
bilateral posterior cortical atrophy (
PCA ) , and whether it is their combination that leads to a severe clinical handicap . -
pubmed
We recorded performance and ocular behavior of four
PCA patients and four age - matched controls in visual search and counting tasks . -
pubmed
Nebivolol to attenuate the effects of
hyper - homocysteinaemia in
rats . -
pubmed
METHODS : Prospectively collected clinical and radiological data of 236
AAA patients , treated at our institution between June 2009 and June 2012 , were retrospectively analyzed regarding the number , location and type of
SRCs and AWHs . -
pubmed
Two hundred thirty - six randomly chosen
patients with
aortoiliac occlusive disease (
AOD ) were recruited as control group . -
pubmed
RESEARCH DESIGN AND METHODS :
Acromegaly patients were identified in two commercial claims databases for this retrospective analysis . -
pubmed
METHODS AND MATERIALS : Eligible
patients had 1 to 3 liver
metastases , maximum sum diameter 6 cm , without extrahepatic progression . -
pubmed
CONCLUSION : SBRT is effective for selected
patients with
hepatic oligometastases with limited toxicities . -
pubmed
METHODS : Sixty
patients with moderate - to - severe
plaque psoriasis were randomized to cohort A : 100 mg , 200 mg or 400 mg
GSK2586184 twice daily or placebo ; and eight were randomized to open - label cohort B , a small exploratory cohort treated with 400 mg
GSK2586184 twice daily , to explore differential gene expression . -
pubmed
CONCLUSIONS : Our study demonstrates that 12 weeks of treatment with
GSK2586184 resulted in clinical improvement and was generally well tolerated in
patients with moderate - to - severe
plaque - type psoriasis . -
pubmed
Lemierre Syndrome of the Femoral Vein , Related to
Fusobacterium necrophorum Abscess of Vastus Lateralis . -
pubmed
BACKGROUND :
Lemierre syndrome is an uncommon , potentially lethal disorder combining
acute oropharyngeal infection caused by
Fusobacterium necrophorum , with
jugular vein suppurative thrombosis , complicated by anaerobic
sepsis with secondary multiple
metastatic abscesses . -
pubmed
CASE REPORT : We present a clinical case of
Fusobacterium necrophorum abscess complicated with
femoral vein thrombosis , called atypical localization of
Lemierre syndrome . -
pubmed
METHOD : Nasal samples were collected from 12
individuals with
asthma and 23 healthy controls early and late in a final exam period , and during a low - stress period in the semester . -
pubmed
RESULTS : Mixed effects analysis of variance models showed that
asthmatic participants with
allergies in contrast to healthy
individuals experienced a decrease in nasal
LTB4 during the final exam period as compared to mid - semester ( low stress period ) . -
pubmed
CONCLUSIONS : Our results suggest that nasal
LTB4 concentrations change in periods of psychological stress for
asthmatic individuals with
allergies . -
pubmed
To date treatment is unable to alter the natural history of
MDS except in those few
individuals who are able to undergo allogeneic progenitor cell transplantation . -
pubmed
METHODS : Seven
phFTD patients without progression or alternative psychiatric diagnosis , 12
bvFTD patients and 17 controls underwent resting state functional MRI ( rs - fMRI ) and diffusion tensor imaging ( DTI ) . -
pubmed
Salmonellosis is one of the most important bacterial
zoonotic diseases transmitted through the consumption of contaminated food , with
chicken and
pig related products being key reservoirs of
infection . -
pubmed
The aim of this study was to evaluate the prognostic significance of total atrial conduction time ( TACT ) assessed by tissue Doppler imaging ( PA - TDI interval ) to predict
AF presence in
patients with
cryptogenic stroke . -
pubmed
METHODS : Ninety
patients ( 57.7 + - 12.3 years , 48 %
women ) after acute
cryptogenic stroke and ICM implantation were prospective recruited at four centers for continuous rhythm monitoring . -
pubmed
Patients were followed up ( 331 + - 186 days ) for detection of
AF ( defined by episode lasting & gt;=30 s ) . -
pubmed
RESULTS :
AF was detected in 16
patients ( 18 % ) during follow - up ( 331 + - 186 days ) . -
pubmed
CONCLUSION : Our data suggest that measurement of TACT could help to predict future
AF detection in
patients with
cryptogenic stroke . -
pubmed
CONCLUSION : Given that
patients with obstructive
anuria can be asymptomatic ,
urolithiasis should be considered in all
patients presenting with
anuria . -
pubmed
Oral administration of both E / E - SBGS and
SBGS significantly suppressed
tumor volume and
tumor weight without gross toxicity in
mice . -
pubmed
Reduced - Concentration
Clavulanate for Young
Children with
Acute Otitis Media . -
pubmed
Amoxicillin -
clavulanate ( A / C ) is currently the most effective oral antimicrobial in treating
children with
acute otitis media (
AOM ) , but the standard dosage of 90 mg
amoxicillin/6.4 mg
clavulanate / kg of
body weight / day commonly causes
diarrhea . -
pubmed
We conducted an open - label study in
children with
AOM who were 6 to 23 months of age . -
pubmed
Rates of
PDD in
children receiving phase 2 and standard regimens were 17 % and 26 % , respectively ( P = 0.10 ) . -
pubmed
Coronary abnormalities were especially high in this group of
patients ( 46 % ) and 9
patients died ( 13 % ) . -
pubmed
METHODS : We analyzed cognitive data from
people with incident late - onset
Alzheimer 's
dementia from a prospective cohort study . -
pubmed
Modeling DNA damage - induced
pneumopathy in
mice : insight from danger signaling cascades . -
pubmed
The resulting pro - inflammatory and pro - angiogenic microenvironment triggers a cascade of events that can lead within weeks to a pronounced
lung inflammation (
pneumonitis ) or after months to excessive deposition of extracellular matrix molecules and tissue scarring (
pulmonary fibrosis).The use of preclinical in vivo models of DNA damage - induced
pneumopathy in genetically modified
mice has helped to substantially advance our understanding of molecular mechanisms and signalling molecules that participate in the pathogenesis of radiation - induced adverse late effects in the lung . -
pubmed
Here we summarize and discuss published data about the role of danger signalling in the response of the lung tissue to DNA damage and its cross - talk with the innate and adaptive immune systems obtained in preclinical studies using immune - deficient inbred
mouse strains and genetically modified
mice . -
pubmed
Leishmania donovani is the causing agent of
visceral leishmaniasis , a common
infection that affects millions of people from the most underdeveloped countries . -
pubmed
Miltefosine is the only oral drug to treat
infections caused by
L. - pubmed
Survival after whole brain radiotherapy for
brain metastases from
lung cancer and
breast cancer is poor in 6325 Dutch
patients treated between 2000 and 2014 . -
pubmed
BACKGROUND : Whole brain radiotherapy ( WBRT ) is considered standard of care for
patients with multiple
brain metastases or unfit for radical treatment modalities . -
pubmed
METHODS : Between 2000 and 2014 , 6325
patients had WBRT ( 20 Gy in 4 Gy fractions ) for brain
metastases from
non - small cell lung cancer (
NSCLC ; 4363
patients ) or
breast cancer (
BC ; 1962
patients ) ;
patients were treated in 15 out of 21 Dutch radiotherapy centres . -
pubmed
FINDINGS : The median survival was 2.7 months for
NSCLC and 3.7 months for
BC patients ( p & lt ; .001 ) . -
pubmed
For
NSCLC patients aged & lt;50 , 50 - 60 , 60 - 70 and & gt;70 years , survival was 4.0 , 3.0 , 2.8 and 2.1 months , respectively ( p & lt ; .001 ) . -
pubmed
For
BC patients , survival was 4.5 , 3.8 , 3.2 and 2.9 months , respectively ( p = .047 ) . -
pubmed
INTERPRETATION : The survival of
patients after WBRT for
brain metastases from
NSCLC treated in Dutch ' common radiotherapy practice ' is poor , in
breast cancer and younger
patients it is disappointingly little better . -
pubmed
Over a period of 12 years ( January 2000 - January 2012 ) , a total of 110
patients with
hyperactive muscles over the frontal region have been collected for a retrospective study . -
pubmed
Toward a noninvasive estimate of interstitial fluid pressure by dynamic contrast - enhanced MRI in a
rat model of
cerebral tumor . -
pubmed
PURPOSE : This study demonstrates a DCE - MRI estimate of
tumor interstitial fluid pressure ( TIFP ) and hydraulic conductivity in a
rat model of
glioblastoma , with validation against an invasive wick - in - needle ( WIN ) technique . -
pubmed
METHODS : The DCE - MRI studies were conducted in 36 athymic
rats ( controls and posttreatment animals ) with implanted
U251 cerebral tumors , and with TIFP measured using a WIN method . -
pubmed
DREADDed microglia in
pain : Implications for spinal inflammatory signaling in male
rats . -
pubmed
Samples from 45
chickens , two
turkeys , one peacock and one quail with symptoms of
fowlpox were collected in Mozambique between November 2016 and January 2018 . -
pubmed
The baseline oral health status of the enrolled
patients was poor and included
edentulism ,
caries ,
gingivitis ,
periodontitis and residual roots . -
pubmed
In addition , innovatively therapeutic strategy of daily drinking PAW on inflammatory - related diseases based on
animal disease models is demonstrated , examples being
chronic kidney disease (
CKD ) ,
chronic sleep deprivation (
CSD ) , and
lung cancer . -
pubmed
A total of 252
parasymphyseal fractures in 200
patients were selected for the study over the period of seven years ( January 2010 - January2017 ) and divided randomly into two groups . -
pubmed
Postoperative
paraesthesia ,
infection , and acceptability of the plate to
patients were also recorded . -
pubmed
Operations were significantly shorter , and significantly fewer
patients developed
paraesthesia or
infection , in the customised group . -
pubmed
Epidemiological investigation and nutritional intervention of
anthocyanins have exhibited broad - spectrum biological effects that they can benefit
patients with
metabolic syndrome related
chronic diseases . -
pubmed
Results : An industry - like SCJ - VHG bioethanol production process with 30 and 35 Bx broth was employed to investigate the effects of both the
yeast strain used and
nitrogen source supplementation on process yield , process productivity , biomass viability ,
glycerol concentration and retention - associated gene expression . -
pubmed
Highest process efficiency , with a 17 % ( w / v )
ethanol yield and only 0.2 % ( w / v )
sugar remaining unfermented , was observed with the
Saccharomyces cerevisiae industrial
strain CAT-1 in 30 Bx broth with
urea supplementation . -
pubmed
SCJ concentrated up to 30 Bx maintains industrially relevant
ethanol production yield and productivity , provided the broth is supplemented with a suitable
nitrogen source and an appropriate industrial
bioethanol - producing
yeast strain is used . -
pubmed
In addition , the work contributes to a better understanding of the VHG - SCJ process and the variable effects of process parameters on process efficiency and
yeast strain response . -
pubmed
Impact of Sensor - Augmented Pump Therapy with Predictive Low -
Glucose Suspend Function on Glycemic Control and
Patient Satisfaction in Adults and Children with
Type 1 Diabetes . -
pubmed
AIMS : The aim was to evaluate the effectiveness of sensor - augmented pump therapy with predictive low -
glucose suspend function (
SAP - PLGS ) in real - world use in
children and adults with
type 1 diabetes (
T1D ) . -
pubmed
METHODS :
Patients with
T1D treated with the MiniMed 640 G pump with PLGS function at three referral hospitals were retrospectively evaluated . -
pubmed
Mean age was 32 + - 17 years , 28 % were ( n = 46 )
children , and 29 % ( n = 47 ) were with a history of severe
hypoglycemia . -
pubmed
Three percent ( n = 5 ) of the
patients experienced severe
hypoglycemia during follow - up . -
pubmed
A total of 22
participants presented for re - treatment of a previously ruptured ( & gt;30 days prior to treatment ) target
aneurysm . -
pubmed
Medline , Embase , the Cochrane controlled trials register , the SCI , ASH , EHA , and ASCO were searched for clinical trials including high - dose chemotherapy plus ASCT for
patients with
NDMM . -
pubmed
ASCT could improve survival than alkylating agent - based regimens plus
lenalidomide consolidations for
patients with
NDMM . -
pubmed
The second
patient was diagnosed with
lipomyelomeningocele during an examination for severe
constipation at the age of 2 years and 8 months . -
pubmed
Bombyx mori bidensovirus infection alters the intestinal microflora of fifth instar
silkworm (
Bombyx mori ) larvae . -
pubmed
Bacterial diseases can occur as a result of disruption of the intestinal microbial population in the
silkworm ,
Bombyx mori , and are often induced by bidensovirus (
BmBDV )
infection . -
pubmed
The research of transgenic
human nucleus pulposus cell transplantation in the treatment of
lumbar disc degeneration . -
pubmed
Immumohistochemical staining , RT - PCR , and western blot were performed to observe the biological effects of double gene - transfected
human nucleus pulposus cells in degenerative lumbar discs on rhesus
lumbar disc degeneration . -
pubmed
Timely detection the side effects of statins makes it possible to diagnose and eliminate , which is crucial for conducting lipid - lowering therapy for
patients with
atherosclerotic cardiovascular diseases . -
pubmed
Escherichia coli was recovered in 34.1 % of culture - positive
UTI episodes , followed by
Proteus mirabilis and
Klebsiella spp , which were recovered in 24.5 % and 17.4 % of culture - positive
UTI episodes , respectively . -
pubmed
Extensive Fatty Replacement of the Pancreas (
Pancreatic Lipomatosis ) in a
Dog . -
pubmed
A 12 - year - old neutered female mixed - breed
dog was referred for occasional
vomiting that had increased progressively in frequency over the past 3 months . -
pubmed
Routine follow - up with the referring veterinarian showed no evidence of
postoperative complications , but the
dog continued to deteriorate further and died despite medical management . -
pubmed
Pancreatic lipomatosis is a rare condition in small
animal practice . -
pubmed
Meanwhile , all isolated compounds were evaluated for their immunosuppressive activities against
mice splenocyte proliferation and antiproliferative activities against
human gastric
adenocarcinoma cells (
SGC-7901 ) ,
human hepatoma (
HepG2 ) , and
human breast cancer (
MCF-7 ) in vitro . -
pubmed
In - vivo cortical thickness estimation from high - resolution T1w MRI scans in healthy and
mucopolysaccharidosis affected
dogs . -
pubmed
Preliminary results of 5 healthy and 5
mucopolysaccharidosis (
MPS )
dogs demonstrate single - canine mean / median cortical thickness in range of 2.69 - 3.58 mm in native space and 3.26 - 4.15 mm in template space . -
pubmed
RESULTS : A total of 212
type 2 diabetic patients aged 40 years or more , and 209 age - matched nondiabetic subjects were included in the study . -
pubmed
About one - quarter of the
diabetics and nondiabetics were positive for
H. - pubmed
We present an unusual case of a 60 - year - old
woman with
myasthenia gravis , who was diagnosed with an incidental
thymoma found on computerised tomography . -
pubmed
METHODS :
Patients with
RA ( symptom duration < 2 years ) were included from two randomised trials : BehandelStrategieen ( BeSt ) , n=508 and Induction therapy with
Methotrexate and
Prednisone in Rheumatoid Or Very
Early arthritic Disease ( IMPROVED ) , n=479 . -
pubmed
METHODS :
Patients treated with radiotherapy for localized
SCCA were included in Aarhus , Denmark from 2016 -2019 . -
pubmed
Baseline levels for
patients with treatment failure ( n=8 ) were above the 25th percentile ( p=0.05 ) which translates into difference in
disease free survival . -
pubmed
If successful , the proposed tools will provide practical screening and streamlined , comprehensive assessments that could be implemented in resource - limited settings to identify children with
cognitive deficits within programmes focused on the care and treatment of children affected by
HIV . -
pubmed
CONCLUSION : Our study shows that overexpression of immunohistochemical parameters together with the negative effects of ischemic and inflammatory processes that subjected to pBOO for 1 , 2 and 3 weeks may play a potential role in detrusor
fibrosis in the
rat bladders induced by pBOO . -
pubmed
H7N9 influenza A virus (
IAV ) is an emerged contagious pathogen that may cause severe
human infections , even
death . -
pubmed
Circular RNAs ( circRNAs ) have been reported to affect the development of
human cancers , including
HCC . -
pubmed
Patients in PG had significantly more often undergone
neuroma resection or stump revision surgery . -
pubmed
The use of dynamic MR - imaging in
patients with clinical
pelvic floor disorders . -
pubmed
METHODS : Fifty
patients ( 44
females , 6
males ; mean age : 57 years ) with symptomatic
pelvic floor dysfunction underwent both examinations , CD and MRD . -
pubmed
, enterotoxigenic
Escherichia coli ,
Clostridium difficile ,
Cryptosporidium parvum ,
Entamoeba histolytica , and
Hepatitis A virus . -
pubmed
METHODS : We tested this hypothesis in the Personalized Prevention of
Colorectal Cancer Trial ( PPCCT ) ( registered at clinicaltrials.gov as NCT01105169 ) , a double - blind 2 x 2 factorial randomized controlled trial enrolling 240
participants at high risk of
Mg deficiency . -
pubmed
From March 1975 until September 1978 , seventy
patients were referred for intra - aortic balloon counterpulsation for
cardiogenic shock complicating
acute myocardial infarction or for the treatment of
low cardiac output states following cardiopulmonary bypass . -
pubmed
Effects on in vitro
tumor growth of
murine macrophages isolated from
sarcoma lines differing in immunogenicity and metastasizing capacity . -
pubmed
Macrophages were isolated from the strongly immunogenic , non - metastasizing
FS6 sarcoma transplanted in syngeneic
C57BL / 6 mice and from a weakly immunogenic , spontaneously metastasizing line (
mFS6 ) of the same
tumor . -
pubmed
Of 200
girls having recurrent
urinary tract infection 43 per cent showed
ureterovesical reflux on the cystogram . -
pubmed
Of 39
boys with recurrent
urinary tract infection 41 per cent had reflux . -
pubmed
Letter :
Haloperidol for acute
amphetamine poisoning : a study in
dogs . -
pubmed
[ Activation of pulmonary macrophage in early stage of experimental acute
pancreatitis in
rat : preliminary report ] . -
pubmed
This is also true with
fibromas because many types of
fibromas would require suturing that would create an inconvenience for the
patient . -
pubmed
CO2 laser surgery performed on the punctata aeriata , interdigital clavus formations , and
hypertrophic scars are not always as successful but offer the surgeon another modality in taking care of the
patient 's problems without the need for extensive surgery . -
pubmed
The cumulative dose response effect of
eicosapentaenoic and docosahexaenoic acid on blood pressure , plasma lipid profile and diet pattern in mild to moderate essential
hypertensive black
patients . -
pubmed
In this study
eicosapentaenoic acid (
EPA ) and
docosahexaenoic acid (
DHA ) were given in a cumulative manner , every 6 weeks , starting with 10 mg , then 100 mg , 1000 mg and 10,000 mg
EPA daily to mild to moderate essential
hypertensive black
patients . -
pubmed
It is therefore concluded that
EPA and
DHA supplementation had no beneficial effects in mild to moderate essential
hypertensive black
patients except for a lowering of plasma AA . -
pubmed
We describe a young
man with radiographic evidence of early onset
bullous emphysema without the usual risk factors and provide a review of the alternative explanations proposed for this form of
lung damage . -
pubmed
We evaluated the neuropsychological functions , rate of
disease progression , and psychiatric characteristics of 22
patients with probable
Alzheimer ' s disease in whom periventricular white - matter radiolucencies (
PWMRs ) were seen on the computed tomographic scan of the brain and compared them with 22 matched
patients with
Alzheimer ' s disease without
PWMRs . -
pubmed
However ,
patients with PWMRs had significantly higher Hachinski Rating scores at both visits and were more likely to develop
cerebrovascular disease during follow - up than were controls with
Alzheimer ' s disease . -
pubmed
Chemoresistance in
rat ovarian tumours . -
pubmed
In a
cisplatin resistant subline (
O-342 / DPP ) of an intraperitoneally growing transplantable
rat ovarian tumour ( O-342 ) , intracellular
glutathione (
GSH ) was approximately doubled ( mean [ S.E. ] -
pubmed
From the sequence information , a synthetic peptide was synthesised which was recognised by one of the monoclonal antibodies directed against the 14 - kDa antigen and a small number of sera from
patients with
onchocerciasis . -
pubmed
After the
patients had been anaesthetized for some time and were haemodynamically stable , profound
bradycardia or
ventricular asystole occurred suddenly in response to manipulations of the bony structures of the maxilla or mandible , or dissection of , or traction on , the attached soft tissue structures . -
pubmed
All
patients undergoing maxillofacial procedures should be monitored carefully for reflex
bradycardia and
ventricular asystole . -
pubmed
In four of these nine
patients there was evidence of an
accessory esophageal disease responsible for the
chest pain . -
pubmed
In 44
patients organic or functional
ischemic heart disease was excluded . -
pubmed
The final results were that 15
patients had
pain of an esophageal origin and 13 had an
esophageal disease that made the esophagus a likely , or at least possible , source of
pain . -
pubmed
Biological markers characterizing the development of preneoplastic and
neoplastic lesions in
rodent liver . -
pubmed
Although no distinct single biochemical marker is ubiquitous to the process of
neoplasia or even to a single histogenetic type of
neoplasm , a variety of histogenetic types of
neoplasms in the
human and experimental
animals exhibit an extreme degree of marker or phenotypic heterogeneity . -
pubmed
Particularly well studied are markers which occurred during the process of hepatocarcinogenesis in the
rodent as well as in its final product , the
hepatoma . -
pubmed
Although phenotypic heterogeneity is characteristic of
hepatocellular carcinomas in both the
rat and
mouse , some degree of predominant marker pattern(s ) has become apparent . -
pubmed
Studies on the transcription of specific genes in
mouse liver as well as preneoplastic and
neoplastic lesions in this tissue further demonstrate the phenotypic heterogeneity characteristic of differentiated
hepatocellular carcinomas . -
pubmed
In general , current evidence supports the two these s that no single biologic marker or set of markers is uniquely characteristic of the preneoplastical and/or neoplastic phenotype and marker or phenotypic heterogeneity is by far the rule rather than the exception in hepatocarcinogenesis in the
rodent and quite possibly in all histogenetic types of
neoplasms in
mammals . -
pubmed
Sodium chloride depletion in a
cat with
fistulated meningomyelocele . -
pubmed
Decreased serum and CSF
chloride concentrations were documented in a 5 - year - old Manx
cat referred for evaluation of
anorexia . -
pubmed
Spinal trabecular bone mineral content in
patients with non - steroid treated
rheumatoid arthritis . -
pubmed
Spinal trabecular bone mineral content was measured in the first , second , and third lumbar vertebrae by quantitative computed tomography in 88
patients with non -
steroid treated
rheumatoid arthritis . -
pubmed
One
vertebral crush fracture was found in one
patient but not in any of the controls . -
pubmed
These results demonstrate a lower spinal trabecular bone mineral content in non -
steroid treated
patients with
rheumatoid arthritis than in age and sex matched controls , the difference being most marked in younger patients . -
pubmed
Alterations of electroencephalogramm and evoked potentials in
brain dead patients are known . -
pubmed
So we analysed those
comatose patients requiring for artificial respiration in whom brain stem acoustic responses could not be evoked . -
pubmed
We found 21
patients out of 103 unselected consecutive
patients with primary
cerebral disease . -
pubmed
All
patients with isoelectric EEG were
brain dead . -
pubmed
Earlier SSEP components were frequent , deformed flash evoked potentials were found in all
brain dead patients . -
pubmed
In all
brain dead patients there was an absence of early acoustic evoked responses and an isoelectric electroencephalogramm . -
pubmed
The Medical Research Council UKALL V trial for
children with standard - risk
acute lymphoblastic leukemia (
ALL ) ( aged 1 to 14 years , leucocyte count less than 20 X 10(9)/L ) was designed to determine whether the immunosuppressive effects of treatment could be reduced without sacrifice of antileukemic effect by alterations in the type of continuing therapy or in fractionation of cranial irradiation . -
pubmed
With a minimum follow - up of almost 7 years ,
patients in group I had significantly fewer remission
deaths ( P = .025 ) but a much higher rate of
bone marrow relapse than those in group C or G ( P = .002 ) . -
pubmed
47
children have been treated in Basel for
aganglionosis (
Hirschsprung ' s disease ) during the last 25 years . -
pubmed
Six
children presented severe
vomiting and an
ileus as leading symptoms instead of chronic
constipation , the classical leading symptom of
Hirschsprung ' s disease . -
pubmed
However , enzyme histochemical and immunocytochemical investigations disclosed an
aganglionosis of the entire colon (
Zuelzer - Wilson ' s disease ) in 3
patients ,
absence of the enteric nervous system in the small and large intestine in 2
patients , and a combination of both in 1 patient . -
pubmed
In contrast to
children suffering from
aganglionosis of the entire colon , the chance of survival for patients with an absence of the enteric nervous system is extremely small . -
pubmed
Constitutional predisposition to
vasovagal syncope : an additional risk factor in
patients exposed to electrical
injuries ? -
pubmed
An hour after a 220 V electric
shock a
patient who was susceptible to mild
vasovagal symptoms in response to emotional stress had a severe episode of
cardiac arrest in response to insertion of a cannula . -
pubmed
Patients with a history of
vasovagal reactions may be at high risk of developing lethal
sinus node or conduction disturbances after electrical
injuries . -
pubmed
To clarify the controversy over whether the neonatal heart is more or less susceptible to global
ischemia than the adult heart , the time interval between the onset of
ischemia and the beginning of
contracture (
TIC ) was compared in neonatal ( n = 6 , 3 to 5 days old ) and adult ( n = 6 , 4 to 5 months old )
pig hearts . -
pubmed
Body surface potential maps were recorded from 140 lead points on the entire chest surface in three groups of subjects : group A consisted of 15
patients with an old inferior
myocardial infarction and typical electrocardiographic signs of
necrosis ; group B consisted of 15
patients with an old inferior
myocardial infarction , but without electrocardiographic signs of
necrosis (
inferior myocardial infarction was documented during the acute phase ) ; group C consisted of 30 healthy controls . -
pubmed
In a randomized trial 49
patients with
fracture of the neck of the femur and an age of less than 70 years or a high level of physical activity were allocated to treatment with a sliding screw plate or a sliding nail plate fixation . -
pubmed
The effect of acute metabolic or respiratory acid - base disturbances on biliary
bicarbonate secretion was examined in bile
fistula rats . -
pubmed
I. Biliary and urinary excretion in normal
rats and with experimental
liver injury ] . -
pubmed
[ Influence of chronic intermittent hemodialysis on lymphocyte stimulation by
PHA in
patients with
terminal kidney failure ] . -
pubmed
Biochemical and electrophoretic studies of -galactosidase in normal
man , in
patients with
Fabry ' s disease , and in Equidae . -
pubmed
[ Upper digestive
hemorrhages in
patients with
gastroduodenal ulcer after administration of ulcerogenic drugs ] . -
pubmed
An experimental comparison between the
ganglion cell receptive field and the receptive field of the adaptation pool in the
cat retina . -
pubmed
Strain differences in susceptibility of
mice and
rats to
cadmium - induced
testicular damage . -
pubmed
Understanding the adaptive struggles of
schizophrenic patients . -
pubmed
Reactivity of sera from
sheep immunised with individual outer membrane proteins of
Bacteroides nodosus against heterologous bacterial
strains . -
pubmed
In order to identify those bacterial antigens which might be involved in immunity against
ovine footrot , antisera were raised in
sheep to 6 proteins in the outer membrane complex ( OMC ) of one
strain of
Bacteroides nodosus . -
pubmed
Subsequent analysis of these sera against 5
strains of
B. - pubmed
Accessory cell function in
tumor - bearing
mice and effects of
Corynebacterium parvum . -
pubmed
For investigation of the mechanism of the immunosuppression in
tumor - bearing
mice and the effects of
C. - pubmed
parvum , the accessory cell function of adherent cells from
tumor - bearing
mice and
C. - pubmed
parvum - treated
tumor - bearing
mice in in vitro cultures was studied . -
pubmed
Peritoneal and splenic cells from
tumor - bearing
mice were less efficient in promoting in vitro production of antibody to SRBC by macrophage - depleted normal nonadherent cells than the adherent cells from normal
mice . -
pubmed
parvum treatment restored the accessory cell function of splenic adherent cells from
tumor - bearing
mice but not that of peritoneal cells . -
pubmed
Furthermore , adherent cells from
tumor - bearing
mice did not show suppressive activity against the in vitro plaque - forming cell response . -
pubmed
This is a retrospective study of 18 acute traumatic tetraplegic
patients admitted to the Cardiff Royal Infirmary within 12 hours of
injury . -
pubmed
Ultraviolet light and
mitomycin C induced sister - chromatid exchanges in fibroblasts from
patients with
retinoblastoma . -
pubmed
A standard feeding procedure may be useful in evaluating
dogs with
gastrinoma . -
pubmed
Effects of systemic
hypertension on ischemic and nonischemic regional left ventricular function in awake , unsedated
dogs after experimental
coronary occlusion . -
pubmed
Hypertension and
atherosclerotic coronary arterial obstruction frequently coexist in
patients . -
pubmed
Systemic
hypertension resulted in a significant increase in endocardial and midwall RMBF and , in seven open - chest
dogs , decreased the intramyocardial accumulation of
carbon dioxide after
LAD occlusion . -
pubmed
Thus , the production of systemic
hypertension with
diastolic pressures of 110 - 120 mm Hg acutely or for 6 hours during evolving
canine myocardial infarction does not appear to exert an important deleterious effect on myocardial
oxygen supply and demand . -
pubmed
A young
man with
visual defect and
galactorrhea . -
pubmed
More than 100 lesions in 38
patients were treated with radiation alone and
hyperthermia in combination with radiation . -
pubmed
Experimental studies on laboratory
rats have shown that solvent mixtures with
n - hexane and
methyl - ethyl - ketone bring about an earlier onset of clinical -
neurological deficits and
hexacarbon - specific morphological changes than exposure to
n - hexane alone . -
pubmed
Hepatic lesions in
Lebistes reticulatus induced by
N - nitrosodiethylamine . -
pubmed
In the later period of the experiment , hyperplastic nodules of hepatocytes ,
cholangiofibrosis ,
cystic cholangiomas ,
hepatocellular and cholangiocellular carcinomas could be observed in the treated
animals . -
pubmed
Aquarium fish can be used as a model for short - term , in vivo
carcinogenesis experiments . -
pubmed
Lebistes reticulatus is a suitable
strain for use as a positive control with NDEA . -
pubmed
Thirty - three
subjects were studied : 6 normal
subjects , 12 with
chronic pancreatitis , 3 after recovery from acute
pancreatitis , 8 with
gall - stones , 3 with
carcinoma of the pancreas and 1 with
cancer of the biliary tract . -
pubmed
The
animals were killed forty - two and eighty - four days after the
injury . -
pubmed
Lipid abnormalities are seen frequently in renal transplant
patients . -
pubmed
Cardiovascular disease is an important cause of morbidity and mortality in these
patients . -
pubmed
Twelve renal transplant
patients who had persistent
hyperlipidemia despite 6 weeks of dietary treatment participated in this prospective , randomized , open - labeled crossover trial . -
pubmed
Although
flushing developed in 67 % of
patients treated with
nicotinic acid , this was not a reason for any of the study dropouts . -
pubmed
administration of 10 mg / kg
body weight to
woodchucks and
Pekin ducks . -
pubmed
MATERIAL AND METHODS : From 1979 to 1982 34
patients underwent surgical correction of a
flexion deformity of the spine in
ankylosing spondylitis . -
pubmed
Moreover , the degradation products of as - polymerized
PLLA bone plates , consisting of numerous stable particles of high crystallinity , are related with a
subcutaneous swelling in
patients 3 yr postoperatively . -
pubmed
Although turtles can serve as alternate hosts for Salmonella , available evidence suggests that turtles in tanks should not be a source of
human infection . -
pubmed
A novel translocation , t(5;14)(q33 - 34;q11 ) , was identified in the leukemic cells of four
children presenting with
acute lymphoblastic leukemia (
ALL ) . -
pubmed
The
patients were 14 months , 2 years , 10 years , and 12 years old ; each presented with one or more features of bulky disease , including
lymphadenopathy ,
organomegaly or a
mediastinal mass . -
pubmed
The
patients with
B - lineage ALL remain in continuous remission at 22 and 19 months following diagnosis . -
pubmed
One
patient with
T - lineage ALL relapsed 6 months after diagnosis . -
pubmed
The other
patient with
T - lineage ALL developed
acute myelocytic leukemia (
AML ) 17 months after diagnosis ; t(5;14)(q33 - 34;q11 ) was present in both the lymphoblasts at diagnosis and the myeloblasts at
relapse , consistent with a lineage switch from
ALL to
AML . -
pubmed
Microsatellite mutation ( CAG24 - ->18 ) in the
androgen receptor gene in
human prostate cancer . -
pubmed
Using the polymerase chain reaction ( PCR ) , we screened 40
human prostate cancer specimens for expansions or deletions of this microsatellite . -
pubmed
MATERIALS AND METHODS : We retrospectively reviewed the radiographs of 80
patients with pathologically proved
gastric carcinoma who had double -
contrast barium studies of the upper gastrointestinal tract between 1985 and 1992 . -
pubmed
The dermatomes below the Th9 lost all somatic sensation on the left side after the nerve blocks , but the
patient was not completely relieved from the
pain . -
pubmed
OBJECTIVE : To study whether fasting and 1 - h postbreakfast C - peptide levels in
NIDDM stabilize with time in individual
patients . -
pubmed
During the treatment of
patients with
renal failure or renal transplants the most important consideration is to eliminate sources of
infection before and after the treatment . -
pubmed
Flow cytometric analysis of neoplastic nodules and
hepatocellular carcinomas induced by
ciprofibrate in the
rat . -
pubmed
Thus , to investigate the role of DNA ploidy changes in development of
HCC , flow cytometric DNA content determinations were done in a
rat model system of peroxisome proliferator - induced
HCC . -
pubmed
CONCLUSION : Laparoscopic appendectomy has significant advantages in terms of
patient comfort and length of stay , and its overall complication rate seems to be lower than with open procedures ; however , its rate of
intra - abdominal abscess may actually be higher . -
pubmed
[ Study on obstructive causes of
internal arteriovenous fistula and prevention in hemodialysis
patients ] . -
pubmed
The interaction between
human endothelial cells ( EC ) and leukocytes during
inflammation is in part mediated through the release of soluble factors . -
pubmed
Fatal
postoperative airway obstruction in a
patient with
rheumatoid arthritis . -
pubmed
We report here the first case of symptomatic acute
hepatic injury due to
midecamycin in a 58 - year - old
man . -
pubmed
Thymic lymphoepithelioma - like carcinoma associated with
thymoma in a
patient with
ocular myasthenia . -
pubmed
A 65 - year - old
woman with
ocular myasthenia was found to have three
tumours in the anterior mediastinum , revealed by magnetic resonance imaging . -
pubmed
METHODS : From January 1 , 1993 , to December 31 , 1997 , all new
patients diagnosed with collagenous or
lymphocytic colitis living in the catchment area of the Hospital Mutua de Terrassa ( Barcelona , Spain ) were identified . -
pubmed
Since 1993 all
patients with
chronic diarrhea were referred for a diagnostic colonoscopy . -
pubmed
Normal rectal biopsies were found in 43 % and 8 % of
patients with collagenous and
lymphocytic colitis , respectively . -
pubmed
To address this and emphasize the role of testicular - sparing surgery in
children , four
patients with
testicular masses are presented who underwent this procedure . -
pubmed
RESULTS : Four
patients whose ages at diagnosis were 1 , 2 , 4 , and 17 years presented with unilateral
testicular masses . -
pubmed
It is a viable and useful method in the management of benign
testicular tumors in
children . -
pubmed
We present a case of
spontaneous rupture of a right coronary bypass vein graft in a 57 - year - old
woman 10 years after coronary by - pass surgery . -
pubmed
HBO
patients with intractable
ETD currently are treated by tympanostomy tube placement ; typically , these tubes are indwelling far longer than is required by the duration of HBO . -
pubmed
Only 1
patient had
otorrhea ; this resolved with dry ear precautions . -
pubmed
Role of
nitric oxide in the autoregulation of renal blood flow and
glomerular filtration rate in aging spontaneously
hypertensive rats . -
pubmed
Autoregulation of renal blood flow ( RBF ) and
glomerular filtration rate (
GFR ) is well maintained in the spontaneously
hypertensive rat ( SHR ) . -
pubmed
The results indicate that in
hypertensive rats with renal
hypertensive damage , the
GFR autoregulation is strongly
NO dependent , as doses of
L - NMMA that do not interfere with the RBF have an effect on the
GFR autoregulation . -
pubmed
Findings from immunization experiments using animal models of experimental
endocarditis support the notion that vaccine development is appropriate for study in
humans , and these findings are reviewed in this paper . -
pubmed
We describe a case of symptomatic
acute infection with
HCV in a woman whose sexual partner had
chronic hepatitis C. -
pubmed
The patient cleared
HCV RNA 8 weeks after the onset of acute
hepatitis and was found to be persistently
HCV - RNA negative during 90 weeks of follow - up . -
pubmed
The resolution of
acute hepatitis C in this case was probably related to the host rather than to intrinsic characteristics of the
HCV genome . -
pubmed
Seven
children ( 0.2 % ) were
visually handicapped ( visual acuity & lt;/=0.3 in the better eye ) . -
pubmed
Alterations of the normal bacterial flora on the exterior genitalia may cause the growth of opportunistic bacteria such as
Klebsiella pneumonia ,
Pseudomonas aeruginosa ,
Streptococcus zooepidemicus , which , if inseminated , may cause
infertility in susceptible mares . -
pubmed
Contagious equine metritis (
CEM ) , a highly transmissible , true
venereal disease of
horses , is caused by the gram - negative coccobacillis ,
Taylorella equigenitalis . -
pubmed
Viruses :
Equine coital exanthema (
equine herpes virus type 3 ;
EHV-3 ) is a highly contagious virus that causes
painful lesions on the stallion 's penis and mare 's vulva . -
pubmed
Protozoa : Dourine , caused by
Trympanosoma equiperidum , is a
venereal disease found only in Africa , South and Central America and the Middle East . -
pubmed
Piroplasmosis , a disease caused by
Babesia equi or by a less severe
strain ,
Babesia caballi , has received a great deal of attention in recent years due to the increased transfer of
horses between countries . -
pubmed
As a group ,
children and
adolescents with
epilepsy have a higher prevalence of
cognitive and behavioral disorders , although many fall within the normal distribution . -
pubmed
Although certain drugs appear more likely to be involved , no single drug causes problems in every
patient , and no drug can be assumed never to cause any
cognitive impairment . -
pubmed
We report a
patient with a
myelopathy in primary
Sjogren ' s syndrome , proven by salivary gland biopsy and specific antibodies . -
pubmed
Under a treatment with
azathioprine and
prednisone the
patient has suffered no
relapse within the last 20 months . -
pubmed
Dynamics of maternal antibodies to
hemorrhagic disease viruses ( Reoviridae : Orbivirus ) in
white - tailed deer . -
pubmed
Enzootic stability , potentially associated with acquired resistance and subsequent transfer of maternal antibodies , innate resistance , or both , has been hypothesized to explain the lack of reports of
hemorrhagic disease (
HD ) in
white - tailed deer (
Odocoileus virginianus ) from Texas . -
pubmed
The objectives of this research were to determine the following : how long maternal antibodies to
epizootic hemorrhagic disease (
EHD ) and
bluetongue (
BT ) viruses persist ; whether fawns from an enzootic site are naturally exposed to
EHD and BT viruses while maternal antibodies are present ; and whether field - challenged fawns develop clinical disease . -
pubmed
This may be due to acquired immunity and the subsequent transfer of maternal antibodies , but it does not exclude innate resistance as a possible factor in the enzootic stability of
EHD and
BT viruses at this location . -
pubmed
Repeat lumpectomy for
patients with ipsilateral
breast tumor recurrence after breast - conserving surgery . -
pubmed
Of 41
patients who had developed
IBTR from October 1986 to June 2000 at our institute , 11 underwent mastectomy of the remaining breast and 30 underwent repeat lumpectomy . -
pubmed
IBTRs in the majority of our
patients were small
lesions less than 1 cm in diameter . -
pubmed
The person currently in most need of an objective viewpoint on
AIDS research , including an outlook on the past , as well as the present and future , is the person who is infected with
HIV . -
pubmed
It delineates potential areas of concern for the
HIV infected patient in the present and future , which may be important directions in the fight against
HIV , both for treatment to evolve to the ideal and for an economically viable treatment for the Third World . -
pubmed
OBJECTIVE :
Stroke is a major complication after coronary surgery , occurring in 1 - 4 % of the
patients . -
pubmed
METHODS : Data from 4567
patients submitted to isolated coronary artery bypass grafting ( CABG ) with hypothermic
ventricular fibrillation between 1992 and 2001 were entered prospectively into a dedicated computerized database and analyzed retrospectively at this time . -
pubmed
RESULTS : The incidence of postoperative
CVA was 2.5 % ( 116
patients ) . -
pubmed
The 30 - day mortality for
patients who experienced a
CVA was 16.4 % versus 0.6 % for
patients who did not ( P<0.001 ) . -
pubmed
Postoperative CVA increased the length of hospital stay threefold to 20.3+/-28.3 days as compared with
patients who did not have a postoperative
CVA ( 7.6+/-4.2 days ; P<0.001 ) . -
pubmed
OBJECTIVES : To determine the number of
children with severe
brain injury due to closed
head injury or
hypoxic - ischemic encephalopathy as a proportion of all admissions of
children & lt;3 yrs of age in the regional pediatric intensive care unit ; to determine the outcome of these
children at & gt;6 mos postinjury ; and to explore the relationship of outcome measures to predictors of outcome obtained within the first 24 hrs after
brain injury . -
pubmed
PATIENTS : Of a cohort of 53
children of & lt;3 yrs of age ( 4 % of pediatric intensive care unit admissions , 1995 - 1998 ) admitted for severe
acquired brain injury ( Glasgow Coma Score , & lt;or=8 ) , 12 ( 23 % ) died , three ( 6 % ) were lost to follow - up , and 38 ( 71 % ) survived and received multidisciplinary outcome assessments . -
pubmed
In
patients with
mitral valve prolapse stress induced
mitral regurgitation has high predictive power for unfavorable clinical course . -
pubmed
Role of
nitric oxide in hemodialysis - related
hypotension in an experimental
renal dysfunction dog model . -
pubmed
In order to create a
renal dysfunction model ,
gentamicin was administered to male
beagles in which 7 of 8 renal artery branches had been ligated . -
pubmed
In renal dysfunctional
dogs , a continuous
hypotension occurred with a gradual increase in the plasma
NOx concentration during
HD . -
pubmed
These results suggest that
NO contributes to
HD - related
hypotension in renal dysfunctional
dogs but the plasma
NOx concentration does not reflect the change in blood pressure . -
pubmed
The sample was composed by 112 Spanish
human services professionals who work with
mentally retarded people . -
pubmed
[ Terminal
ileitis in a young
man with
Schoenlein - Henoch purpura ] . -
pubmed
METHODS : We prospectively studied 50
CVT patients from Brazil , comparing clinical and laboratory data among white ( W ) and African - Brazilian ( AB )
patients . -
pubmed
RESULTS : Seventy percent of the
patients were female , 26 W and 23
AB , mean age 34.7 years . -
pubmed
Losartan increases
bradykinin levels in
hypertensive humans . -
pubmed
Non -
neoplastic process after neck dissection demonstrated on enhanced CT in
patients with
head and neck cancer . -
pubmed
Non invasive evaluation of endothelial function in
patients with
Anderson - Fabry disease . -
pubmed
Patients ' exclusion criteria included a prior history of
cardiac disease ,
diabetes and treated or untreated
hypertension . -
pubmed
Patients underwent : anamnesis , physical examination , EKG , 2 - dimensional echocardiography with tissue Doppler , measurement of
body weight and height , blood pressure . -
pubmed
CONCLUSIONS : Our study demonstrated the presence of
endothelial dysfunction in
patients with
Fabry ' s disease in comparison to controls . -
pubmed
We hypothesized that
endothelial dysfunction may contribute to the pathogenesis of ischemic events in
patients with
Fabry ' s disease . -
pubmed
This paper presents two
patients with
rhinocerebral mucormycosis , both suffering from
diabetes . -
pubmed
Complete recovery was achieved in one
patient with surgical debridement of
necrotic tissue combined with systemic antifungal treatment , whereas in the other , the disease was complicated with
subarachnoid hemorrhage and the
patient died on the third day of treatment . -
pubmed
A 64 - year - old
man with unresectable sigmoid
adenocarcinoma due to peritoneal dissemination ( P3 ) and liver metastasis ( H2 ) treated with
TS-1 , showed a complete response . -
pubmed
OBJECTIVE : To study the effects of a special nutritional supplement on bone mineral density and bone turnover markers in Chilean elderly
subjects with
femoral osteoporosis . -
pubmed
SUBJECTS : Free living elderly
subjects with
femoral osteoporosis . -
pubmed
In addition , emerging pathogens such as
BK polyomavirus and
West Nile flavivirus infections and the introduction of newer immunosuppressive agents that constantly change the risk profiles for
opportunistic infections has added layers of complexity to this burgeoning field . -
pubmed
Most of the reviews described in detail several aspects of
HIV tropism , viral entry mechanism , coreceptor usage and its implication on
disease progression , antiretroviral therapy , and vaccine development . -
pubmed
Protective effects of hyperoxygenated solution preconditioning on intestinal
ischemia -
reperfusion injury in
rabbits . -
pubmed
BACKGROUND : The aim of this study was to investigate the protective effects of hyperoxygenated solution ( HOS ) preconditioning on intestinal
ischemia - reperfusion ( IR ) injury in
rabbits . -
pubmed
MATERIALS AND METHODS : Thirty - two
rabbits were randomly divided into four groups as follows : ( 1 ) control group in which sham operation was performed ( Sham group ) ; ( 2 ) sham operation and HOS treatment group ( sham+H group ) ; ( 3 )
ischemia - reperfusion group ( IR group ) ; ( 4 )
ischemia - reperfusion and HOS treatment group ( H group ) . -
pubmed
The sequencing of their genomes has revealed that a surprisingly large proportion of genes relevant for
human disease have counterparts in the worm and in the
fly . -
pubmed
We present our experience with a
patient in whom a homograft conduit was used to connect the superior vena cava ( SVC ) to the right pulmonary artery ( RPA ) in a functionally
univentricular heart where corrective repair was impossible . -
pubmed
Characterization of
human prostate and
breast cancer cell lines for experimental T cell - based immunotherapy . -
pubmed
METHODS : To assess the relative contribution of
infection and drugs , we compared the expression of marker genes corresponding to mitochondrial function , adipocyte differentiation and metabolism , and adipokines in subcutaneous adipose tissue from healthy controls , untreated
HIV-1 - infected
patients , and
HIV-1 - infected patients treated with HAART with or without HALS . -
pubmed
CONCLUSIONS : Disturbances in adipose tissue gene expression are already present in untreated
HIV-1 - infected patients , thus indicating a role of
HIV-1 infection itself in eliciting adipose tissue alterations that are worsened by HAART , which ultimately leads to
HALS . -
pubmed
Of the 3,400
hypertensive patients included in the study , 315 ( 9.3 % ) patients ( mean age : 66.9+/-10.4 years ; males : 43.5 % ) were prescribed diuretics . -
pubmed
In mosaic arthroplasty defects of live
sheep ,
bleeding occurred beneath part of the hydrogel carrier , and the gel was cleared after 1 month in vivo . -
pubmed
Louis encephalitis virus ,
West Nile virus , and consensus sequences for tick - borne
encephalitis complex groups : Russian Spring - Summer
encephalitis and
Central European encephalitis viruses . -
pubmed
Similarly , in portal
hypertensive rats portal systemic shunting measured by intrasplenic injections of radiolabelled
cobalt microspheres ( 37.1 + /- 3.9 % ) was significantly greater ( p & lt ; 0.005 ) than in control animals . -
pubmed
Pyridoxine supplementation for the treatment of
levetiracetam - induced
behavior side effects in
children : preliminary results . -
pubmed
Here we apply the integrative genomics principles to interrogate relationships between structural features and gene expression patterns of disease - linked SNPs , microRNAs and mRNAs of protein - coding genes in association to phenotypes of 15 major
human disorders , namely
bipolar disease (
BD ) ;
rheumatoid arthritis (
RA ) ;
coronary artery disease (
CAD ) ;
Crohn ' s disease (
CD ) ;
type 1 diabetes (
T1D ) ;
type 2 diabetes (
T2D ) ;
hypertension (
HT ) ;
ankylosing spondylitis (
AS ) ;
Graves ' disease (
autoimmune thyroid disease ;
AITD ) ;
multiple sclerosis (
MS ) ;
breast cancer (
BC ) ;
prostate cancer (
PC ) ;
systemic lupus erythematosus (
SLE ) ; vitiligo - associated
multiple autoimmune disease (
VIT ) ; and
ulcerative colitis (
UC ) . -
pubmed
Our analysis reveals a systematic primary sequence homology / complementarity - driven pattern of associations between disease - linked SNPs , microRNAs and protein - coding mRNAs defined here as a
human disease phenocode . -
pubmed
This review is intended as a first step to develop an instrument for identifying
patients at high risk for
CPSP , to optimize clinical
pain management . -
pubmed
This report stresses the importance of early , minimally interrupted , chest compression CPR in
children who suffer
sudden cardiac arrest in the out - of - hospital setting where defibrillation could be delayed . -
pubmed
A series of images in localized fibrinolytic treatment for a
patient with acute
superior mesenteric artery thromboembolism . -
pubmed
Antitumor effect of pretreatment for
colon cancer cells with
hyperthermia plus
geranylgeranylacetone in experimental
metastasis models and a subcutaneous
tumor model of
colon cancer in
mice . -
pubmed
For in vivo study , colon26 cells were injected via the tail vein or into a subcutaneous area of
mice and the numbers of lung metastatic nodules or the volumes of subcutaneous
tumors were assessed . -
pubmed
The Safe Implementation of Thrombolysis in
Stroke Monitoring Study ( SITS - MOST ) of 6,483
patients treated with intravenous
alteplase within 3 h after
stroke onset showed that this treatment was as safe and as effective in clinical practice as in randomized controlled trials . -
pubmed
After SITS - MOST , the registry is generating new information on outcome predictors , treatments in patients in later time windows ,
patients with hyperdense
middle cerebral artery signs , and several publications are in preparation . -
pubmed
[ Galavit - induced change of immunologic parameters in
patients with
non - small lung cancer ] . -
pubmed
Our results show that similar to other molecular chaperones , both
human and parasite TCTPs can bind to a variety of denatured proteins and protect them from the harmful effects of thermal
shock . -
pubmed
ATL - like marked atypical
lymphocytosis associated with drug - induced
hypersensitivity syndrome and
human herpesvirus-6 reactivation . -
pubmed
BACKGROUND : It has been reported that manipulative therapy directed at the cervical and thoracic spine may improve outcomes in
patients with
shoulder pain . -
pubmed
To date , limited data are available to help physical therapists determine which
patients with
shoulder pain may experience changes in
pain and disability following the application of these interventions . -
pubmed
OBJECTIVE : The purpose of this study was to identify prognostic factors from the history and physical examination in
individuals with
shoulder pain who are likely to experience rapid improvement in
pain and disability following cervical and thoracic spine manipulation . -
pubmed
influenzae
strains and all 110 ( 100 % )
H. - pubmed
influenzae
strains were
H. - pubmed
Screening of genes involved in chromosome segregation during meiosis I : toward the identification of genes responsible for
infertility in
humans . -
pubmed
To identify candidate genes responsible for
infertility in
humans , we performed gene expression profiling of
mouse spermatogenic cells undergoing meiotic prophase I. -
pubmed
These 726 candidates for
human infertility genes might serve as a useful resource for next - generation sequencing combined with exon capture by microarray . -
pubmed
RESULT(S ):
Cetrorelix inhibited ovulation in
mice , as shown by an increase in number of tertiary follicles concomitant with a significant inhibition of follicle
rupture and corpora lutea formation . -
pubmed
A semi - structured questionnaire was administered to consecutive consenting caregivers of
HIV - infected children aged & gt;=6 years attending the Paediatric
Infectious Disease Clinic of the University College Hospital , Ibadan , between November 2008 and October 2009 . -
pubmed
METHODS :
Sheep ( n = 15 ) underwent intracoronary sphere injection to create chronic
ischemic heart failure . -
pubmed
[ Occurrence of
struma ovarii among
women operated for
ovarian teratoma ] . -
pubmed
Authors reviewed the records of 94
patients operated for
ovarian teratoma in their department between 1986 and 2002 , of which 3 patients proved to have
struma ovarii . -
pubmed
They found that the 3
patients had highly variable clinical symptoms and morphological characteristics including
tumor size ,
pain as main symptom , and the presence or absence of
ascites and hormonal activity . -
pubmed
Al - treated
rats showed lower
body weight , lower serum pH , higher accumulation of
Al , in addition to disordered metabolism of
calcium and
phosphorus compared with control
rats . -
pubmed
These findings suggest that long - term
Al exposure in an acidic condition inhibits bone formation and induces
bone loss in young growing
animals . -
pubmed
Thus , in vivo experiments on trabecular bone healing and
osteoporosis research for application in
humans can be conducted in
ovine ,
bovine , or
porcine species . -
pubmed
Mineralocorticoid receptor antagonists ( MRAs ) have been effective in reducing total mortality in
patients with
heart failure (
HF ) and a reduced left ventricular ejection fraction . -
pubmed
Role of
etravirine in the management of treatment - experienced
patients with
human immunodeficiency virus type 1 . -
pubmed
Its safety profile is comparable to placebo with the exception of
rash , which has been mild and self - limited in the great majority of
patients . -
pubmed
METHODS : We analyzed MUPs recorded from biceps brachii muscle , including 209 associated with
ALS ( 12
patients ) and 127 with
SMA ( 5
patients ) . -
pubmed
Analysis of
variola and
vaccinia virus neutralization assays for
smallpox vaccines . -
pubmed
Possible
smallpox reemergence drives research for third - generation vaccines that effectively neutralize
variola virus . -
pubmed
A comparison of neutralization assays using different substrates ,
variola and
vaccinia ( Dryvax and modified
vaccinia Ankara [ MVA ] ) , showed significantly different 90 % neutralization titers ; Dryvax underestimated while
MVA overestimated
variola neutralization . -
pubmed
Thirty years after the discovery of the
human immunodeficiency virus (
HIV ) as the cause of
acquired immunodeficiency syndrome (
AIDS ) , no effective vaccines are available and there is no cure for the disease . -
pubmed
The ACI
rat model of
17beta - estradiol ( E2)-induced
mammary cancer has gained wide use in the study of
breast cancer etiology , prevention , and genetics . -
pubmed
The method is simple and fast for the preliminary pharmacokinetic study of
cefuroxime lysine in
liver - injured rats . -
pubmed
The effect of semelil ( angipars ) on
bone resorption and bone formation markers in
type 2 diabetic patients . -
pubmed
METHODS : In this randomized , double- blind clinical trial , 61
diabetic patients were included . -
pubmed
A QTL analysis was conducted with
disease severity and
infection type data obtained by controlled inoculation of the population with each of two previously characterized pathotypes of
Puccinia graminis subsp . - pubmed
Ethanol extract of
Peperomia pellucida (
Piperaceae ) promotes
fracture healing by an anabolic effect on osteoblasts . -
pubmed
MATERIALS AND METHODS :
Ethanol extract of
Peperomia pellucida was administered at 100 and 200mg / kg doses orally to adult female
Sprague - Dawley rats having a
drill hole injury ( 0.8 mm ) in the femur diaphysis . -
pubmed
RESULTS :
Ethanol extract from
Peperomia Pellucida ( L. ) dose - dependently induced bone regeneration at the
fracture site . -
pubmed
CONCLUSION : Ethanolic extract of P. pellucid ( L. ) accelerates
fracture repair in
rats via stimulatory effects on osteoblast differentiation and mineralization , thereby justifying its traditional use . -
pubmed
The
cancers in these
mice are moderately differentiated invasive mucinous
adenocarcinomas of the proximal colon that develop by 50 days of age . -
pubmed
In vivo studies were carried out for the promising formulation on eyes of albino
rabbits by inducing
bacterial keratitis . -
pubmed
We review demographic trends shaping the difficulties in providing care to incarcerated people with
HIV and recommend the Centers for
AIDS Research Collaboration on
HIV in Corrections as a model of interdisciplinary collaboration in addressing those difficulties . -
pubmed
Induction of apoptosis by
grape seed extract (
Vitis vinifera ) in
oral squamous cell carcinoma . -
pubmed
This study is the first to investigate the
cytotoxic effects and the mechanism of cell
death induced by
grape seed extract ( GSE ) in
oral squamous cell carcinoma ( KB cells ) . -
pubmed
METHODS : This was a substudy of a randomized single - blinded clinical trial reported earlier on
critically ill patients with clinical
hypovolemia after cardiac or major vascular surgery . -
pubmed
CONCLUSIONS : An increase in SvO2 & gt;=2 % , irrespective of a relatively high baseline value , can thus be used as a monitor of fluid responsiveness in clinically
hypovolemic patients after cardiac or major vascular surgery , particularly in those with systolic
cardiac dysfunction . -
pubmed
We included 43
patients with sporadic
FTLD -
TDP , type A , B , or C , from 269 consecutively autopsied
patients with
TDP-43 proteinopathy . -
pubmed
Patients were categorized as having
FTLD without
ALS ,
FTLD -
ALS ( onset of
FTLD symptoms / signs preceded those of
ALS ) , or
ALS -
FTLD ( onset of
ALS symptoms / signs preceded those of
FTLD ) . -
pubmed
All the
patients with type A or C
FTLD -
TDP were included in the
FTLD without
ALS group , and all those with type B pathological changes were in the
FTLD - ALS or the
ALS - FTLD group . -
pubmed
An evaluation of the safety and efficacy of
cariprazine in
patients with acute exacerbation of
schizophrenia : a phase II , randomized clinical trial . -
pubmed
This study ( NCT00694707 ) evaluated the efficacy and safety of
cariprazine in
patients with acute exacerbation of
schizophrenia . -
pubmed
CONCLUSION : The results of this study support the efficacy and safety of
cariprazine in
patients with acute exacerbation of
schizophrenia . -
pubmed
METHODS :
Rats with
visceral hypersensitivity were generated using neonatal colon
irritation during postnatal days 8 - 15 as described previously . -
pubmed
Abdominal withdrawal reflex ( AWR ) scores and
pain thresholds were also detected in adult
rats . -
pubmed
The
pain threshold in
rats with
visceral hypersensitivity significantly decreased compared to control
rats ( P & lt ; 0.05 ) . -
pubmed
Many
hyperthyroid cats develop
azotaemic chronic kidney disease (
aCKD ) following treatment , which has led to the hypothesis that
hyperthyroidism might be detrimental to renal function . -
pubmed
Therefore , tubular
hypoxia may not be a mechanism for
renal damage in
hyperthyroid cats . -
pubmed
The final valve position was adequate in 91.2 % of the Case
patients and in 97 % of the Control
patients , with no cases of valve migration or
coronary obstruction . -
pubmed
METHOD : Forty -
women with primary
breast cancer undergoing a modified radical mastectomy were randomized to receive postoperative analgesia with
flurbiprofen axetil combined with
fentanyl or
fentanyl alone . -
pubmed
However , it is now becoming increasingly clear that MVs are also stable in the circulation of
cancer patients , where they can mediate long - range effects and contribute to the formation of the pre - metastatic niche , an essential step in
metastasis ( Skog et al . -
pubmed
, Nat Med 18:1835 - 1840 , 2012 ) , point to critically important roles for MVs in
human cancer progression that can potentially be exploited to develop new targeted approaches for treating this disease . -
pubmed
MATERIAL AND METHODS : Examinations of 20
MS patients ( 10
women , 10
men ) were reviewed retrospectively . -
pubmed
CONCLUSION : 3D FLAIR sequences can improve the detection of
brain lesions in
patients with
MS and are even more sensitive in depicting lesions in cortical and infratentorial locations than current dual - echo sequences . -
pubmed
BACKGROUND : In our Institute , most of the
patients treated for
hand injuries were industrial
workers with poor compliance . -
pubmed
A total of 100
patients and 139 digits with
zone II flexor tendon injuries were studied . -
pubmed
Treatment of
hypercholesterolemia : screening of
Solanum macrocarpon Linn (
Solanaceae ) as a medicinal plant in Benin . -
pubmed
The present study is conducted to evaluate the lipid lowering activity of leaves and fruits of
Solanum macrocarpon , a vegetable , on
Wistar rats experimentally rendered
hypercholesterolemic by
Triton X-100 . -
pubmed
for 7 days to
rats at doses of 400 and 800 mg / kg of
body weight . -
pubmed
Hepatic disorders due to the
Triton have been corrected by
S. - pubmed
CONCLUSIONS : This vegetable effectively suppresses experimental
hypercholesterolemia in
Wistar rats , suggesting a protective role in
cardiovascular diseases . -
pubmed
BACKGROUND : Combined heart - liver transplantation ( CHLT ) is an uncommonly performed procedure for
patients with coexisting
cardiac and liver disease . -
pubmed
CONCLUSION : Combined heart - liver transplantation is a life - saving operation that is performed with relatively low mortality and can be successfully performed in select
patients with congenital or acquired
cardiac disease . -
pubmed
A 37 - year - old
woman was referred to our institution for further management of a
mass lesion located in the thoracic cavity . -
pubmed
The
patient had complained of left - sided
flank pain for a year and experienced
dyspnea for one month . -
pubmed
The
patient underwent adjuvant chemotherapy and has been doing well without any evidence of
recurrence for 14 months . -
pubmed
We report draft genome sequence of
Ochrobactrum intermedium strain 229E concurrent with
Helicobacter pylori in urease positive gastric biopsy of
non - ulcer dyspeptic individual from Southern part of India . -
pubmed
intermedium 299E
strain revealed functional similarities with virulence related gene clusters present in
H. - pubmed
[ Inhibitory effects of
Kukoamine B on the inflammatory response of small intestine in lipopolysaccharide - induced
septic mice and its potential mechanisms ] . -
pubmed
OBJECTIVE : To study the role of
Kukoamine B ( KB ) in inhibiting the inflammatory response of small intestine in
septic mice and its molecular mechanisms . -
pubmed
MATERIAL AND METHODS : We performed a cross - sectional study among
patients with
liver disease ,
inflammatory bowel disease ,
cancer or
pancreatitis . -
pubmed
METHODS : Case studies on two
patients with
LAHS were reviewed , details on their presentation , work up and management were extracted . -
pubmed
Additionally the review of the literature reveals that there are 15 case reports and 5 case series that report 25
children with
LAHS - AI , 9 case reports and 6 case series report 26
children of
LAHS associated with
viral infections (
LAHS - VI ) . -
pubmed
All
patients with
LAHS - AI had a protracted course and needed prolonged treatment with immune - suppressive therapy while
patients with LAHS - VI resolved spontaneously or needed short - term immune - modulating therapy . -
pubmed
METHODS : We compared intestinal microbiota of
patients with
IF ( n = 23 ) with healthy controls ( n = 58 ) using culture - independent phylogenetic microarray analysis . -
pubmed
METHODS : One hundred twenty - eight
patients were treated with
PVP for
osteoporotic vertebral compression fracture (
VCF ) where 46
patients underwent
PVP with JN needle and 82
patients with BVF . -
pubmed
Effects of alkylation and immunopotentiation against Ehrlich
ascites murine carcinoma in vivo using novel
tetra - O - acetate haloacetamido carbohydrate analogs . -
pubmed
In vitro , IC50 values of all four
Tet - OAHCs were determined against Ehrlich
ascites murine carcinoma , as well as two
leukemias (
U937 human monocytic leukemia and
L1210 murine lymphoid leukemia ) to assess their
cytotoxicity in multiple neoplastic cell lines . -
pubmed
3 ) The analogs demonstrate marked in vivo activity in both B6D2F1 and
CD2F1 mice challenged with a lethal dose of
Ehrlich ascites carcinoma , and frequently produce long term survival at 60 days , which is not observed in simple
halo derivatives or two currently approved antineoplastic agents (
daunorubicin and
mechlorethamine ) . -
pubmed
Pre - clinical neurobiological models of
addiction etiology including both the allostatic model and incentive sensitization theory suggest that
alcohol consumption among
alcohol - dependent (
AD )
individuals will be dissociated from hedonic reward as positive reinforcement mechanisms wane in later stage dependence . -
pubmed
Dual grading were performed with adjudication of admission
fluorescein images from a large cohort of
children with
cerebral malaria . -
pubmed
Documentation of
renal glomerular and tubular impairment and
glomerular hyperfiltration in multitransfused
patients with
beta thalassemia . -
pubmed
We aimed to assess the frequency and predictors of
glomerular and tubular defects ,
renal impairment , and
hyperfiltration in 96 adult
patients with
beta thalassemia intermedia and major . -
pubmed
Renal glomerular and / or tubular defects were observed in about 68.8 % of all
patients . -
pubmed
Forty percent of
patients had
glomerular hyperfiltration . -
pubmed
Renal tubular and glomerular damage is frequent in adult
patients with
thalassemia intermedia and major . -
pubmed
This retrospective study concerns 53
patients aged 16 to 55 years , hospitalized for
hemorrhage stroke in the neurological department of Fann Teaching Hospital during 2010 . -
pubmed
Hypertension was found in 62 % of the
patients , and 11 % had a history of
stroke . -
pubmed
During the acute phase of
hemorrhage , glycemic levels were high among one third of the
patients . -
pubmed
Curative intravenous
quinine treatment was used in 154/155
patients with severe
malaria and
atovaquone /
proguanil in 74 % of
patients with
uncomplicated malaria . -
pubmed
Hospital mortality was 5.2 % ( 8
patients ) , all in the severe
malaria group . -
pubmed
METHODS : We reviewed medical records of
children with
diabetes diagnosed before 12months of age . -
pubmed
RESULTS : 12
patients were diagnosed with
diabetes before 6months of age (
PNDM=6 ;
TNDM=6 ) , and 11 patients between 6 and 12months ( all with permanent
diabetes ) . -
pubmed
CONCLUSIONS : Investigating the underlying genetic basis of
diabetes in
children with onset before 1year is useful for choosing the most efficient treatment , the basis of Personalized Medicine . -
pubmed
Patients with
chronic insomnia have selective impairments in memory that are modulated by
cortisol . -
pubmed
The participants in this study were selected from the clinical setting and included 21
patients with
chronic insomnia disorder (
CID ) , 25
patients with
insomnia and comorbid
depressive disorder (
CDD ) , and 20 control participants without
insomnia . -
pubmed
Compared to the controls , the
CID patients made significantly more errors in spatial working and object recognition memory ( p & lt ; .05 ) , whereas the
CDD patients performed poorly in all the assessed memory types ( p & lt ; .05 ) . -
pubmed
After controlling for confounding variables , the partial correlation analysis revealed that the levels of
cortisol positively correlated with the errors in object working memory ( r = .534 , p = .033 ) and negatively correlated with the errors in object recognition memory ( r = -.659 , p = .006 ) in the
CID patients . -
pubmed
The results suggest that the
CID patients had selective
memory impairment , which may be mediated by increased
cortisol levels . -
pubmed
CASE REPORT : A 35 - year - old
woman presented with
waist pain for over 1 month . -
pubmed
Retinal sensitivity after selective retina therapy ( SRT ) on
patients with
central serous chorioretinopathy . -
pubmed
PURPOSE : To assess retinal sensitivity after selective retina therapy ( SRT ) in
patients with
central serous chorioretinopathy (
CSCR ) . -
pubmed
METHODS : Seventeen eyes of 17
patients with
CSCR lasting longer than 3 months were treated with SRT ( wavelength 527 nm Nd : YLF laser , 50 - 150 muJ /
pulse ,
spot diameter 200 mum ) . -
pubmed
In seven of them , a paramedian ITSC transcollicular approach was used to resect intrinsic
mid - brain lesions , and in the other nine
patients , an intermediate or lateral ITSC infra - trochlear approach was used for
ponto - mesencephalic lesions . -
pubmed
In seven
patients with
mid - brain lesions , the preoperative ocular symptoms improved in three of them , and the
neurological deficits - other than ocular symptoms improved - in five of them . -
pubmed
In nine
patients with a
ponto - mesencephalic lesion , the preoperative ocular symptoms improved in four of nine
patients , and the
neurological deficits other than ocular symptoms improved in five of them , while one
patient exhibited
venous infarction in a cerebellar hemisphere that caused
neurological deterioration . -
pubmed
Additionally , the treatment was further analyzed with respect to models of
AD and
PD in
mice . -
pubmed
Auditory hallucinations constitute an important symptom component in 70 - 80 % of
schizophrenia patients . -
pubmed
In this study , we describe the development of an auditory signal detection task using a carefully chosen set of English words that could be tested successfully in
schizophrenia patients coming from varying linguistic , cultural and social backgrounds . -
pubmed
Schizophrenia patients with significant
auditory hallucinations ( N=15 ) and healthy controls ( N=15 ) performed the auditory signal detection task wherein they were instructed to differentiate between a 5 - s burst of plain white noise and voiced - noise . -
pubmed
Impaired reproduction in Japanese Black
cattle under cold environmental conditions . -
pubmed
Structural lesions were seen in 74
patients ( 67 % ) and
inflammatory lesions in 88 ( 79 % ) . -
pubmed
CONCLUSION : This prospective observational cohort study in daily clinical practice shows a high prevalence of structural and inflammatory US lesions in
AS patients with longstanding and active disease . -
pubmed
METHODS : Clinical trial , double - blind , crossover , in which we evaluated healthy adolescent
athletes with
allergic rhinitis , using experimental and placebo ENDs , submitted to a maximum cardio - respiratory test in randomized order . -
pubmed
RESULTS : 65
adolescents participated in the study , 30 of whom had
allergic rhinitis . -
pubmed
Reperfusion Options for
ST Elevation Myocardial Infarction Patients with Expected Delays to Percutaneous Coronary Intervention . -
pubmed
METHODS : Whole blood gene expression profiles , performed using the Illumina HT-12v4
Human Expression Beadchip , were compared between ( i ) individuals with
obesity ( O ) or lean ( L ) individuals ( n=21 each ) , ( ii ) individuals with ( M ) or without ( H )
Metabolic Syndrome ( n=11 each ) matched on age and gender . -
pubmed
In large
human cohort studies , bilateral hippocampal structures are frequently identified and measured to gain insight into
human behaviour or genomic variability in
neuropsychiatric disorders of interest . -
pubmed
CLINICAL REPORT : We have presented the case of a
patient who developed a delayed
pruritic , and
erythematous maculopapular skin exanthema after the intake of
amlodipine . -
pubmed
ETHNOPHARMACOLOGICAL RELEVANCE :
Cordyceps sinensis is a traditional Chinese medicine and has been used as adjuvant treatments for
cancer and it has been also demonstrated to be effective in
cancer patients . -
pubmed
AIM OF THE STUDY : The objective of the present study is to investigate the anti -
metastasis effects of water extracts of
Cordyceps sinensis ( WECS ) in
breast cancer and the potential mechanisms . -
pubmed
The in vivo anti - metastatic activity of intraperitoneally administered WECS and its effect on animal survival were measured in a
mouse breast cancer metastasis model . -
pubmed
In animal studies , 50mg / kg WECS significantly reduced the number of metastatic lung nodules and the weight of lung , without affecting
body weight of
mice . -
pubmed
Furthermore , WECS increased the survival rate of
4T1 tumor bearing
mice in a dose dependent manner , and at high dose , WECS ( 50mg / kg ) significantly increased the life span of the
mice compared to untreated control group . -
pubmed
Staphylococcus aureus is the major cause of
foodborne diseases worldwide . -
pubmed
One isolate was obtained from a pet (
dog ) , one from an exotic animal ( a circus elephant ) , and four
human isolates were obtained during a severe
food poisoning outbreak that occurred in Sicily in 2015 . -
pubmed
We also determined lethal
toxicity of the venom ( LD50 : 9.17 mug per
mouse ) , and established the assay for the determination of an anti - lethal titer of antivenom in
mice . -
pubmed
BACKGROUND : While it is known that
perfluoroalkyl substances ( PFASs ) induce
liver toxicity in experimental studies , the evidence of an association in
humans is inconsistent . -
pubmed
METHODS : A total of 69
rectal cancer patients from a single referral surgical unit who had a loop ileostomy during low anterior resection of the rectum were included in this study . -
pubmed
Atorvastatin - Associated
Macroglossia in a
Cardioembolic Stroke Patient . -
pubmed
A single session of visual feedback improves range of motion in
patients with chronic
idiopathic neck pain : A randomized and controlled study . -
pubmed
OBJECTIVE : The clinical challenge in
blunt nasal trauma in
children , is to identify cases requiring specialized care among frequently encountered banalities , whilst trying to minimize the exposure to diagnostic procedures . -
pubmed
METHODS : This retrospective cohort study includes
children up to 16 years presenting at the emergency department with
blunt nasal trauma of our tertiary reference center . -
pubmed
Additionally , they did not evidence any accurate
cytotoxicity when incubated with healthy
human foreskin fibroblast ( BJH ) cells for doses as high as 50 mug mL-1 and contact time as long as 48 h , highlighting the ability of the prepared particles to be used as efficient down - converter light sources for cell labelling . -
pubmed
Broiler chicken meat is considered as the main source of foodborne
Campylobacter infection . -
pubmed
Campylobacter jejuni multilocus sequence type ST-5 has been previously identified as predominant among Latvian and Lithuanian broiler
chicken meat products and is often isolated from Lithuanian patients with
Campylobacter enteric infection . -
pubmed
RESULTS : Twenty - two GFFs ( unilateral n = 8 ; bilateral n = 7 ) were performed in 15
patients ( nine
women and six
men ; anal squamous cell
carcinoma n = 8 ; rectal
adenocarcinoma n = 7 ; mean age 65.5 + 8.2 years ) with a mean follow - up time of 1 year . -
pubmed
Methods : First , we transplanted autologous nucleus pulposus into dorsal root
ganglions to establish chronic
radiculitis in
rats . -
pubmed
Results : Chronic
radiculitis was established in
rats . -
pubmed
Acute stroke care should be reorganized by making use of the examples of workflow interventions described in this review to ensure the best medical care for
stroke patients . -
pubmed
Prominent for its resilient
mutagenicity and toxicity ,
DBF poses a major challenge to
human health . -
pubmed
In the present study , a new
strain of
Pseudomonas aeruginosa ,
FA - HZ1 , with high
DBF - degrading activity was isolated and identified . -
pubmed
A total of 1459 proteins were identified in
strain FA - HZ1 , of which 100 were up - regulated and 104 were down - regulated . -
pubmed
Case presentation An 11 - year - old
boy presented with severe
hypertension (
HTN ) with
cardiac target organ damage . -
pubmed
Signs and symptoms attributable to ectopic hormones should be investigated in
PCC patients . -
pubmed
This indicates that premenopausal
women may experience protection against deleterious effects of acute
hyperglycemia , regardless of menstrual cycle phase . -
pubmed
However , research in healthy premenopausal
women is lacking and the impact of menstrual phase [ early follicular ( EF ; low
estrogen ) and late follicular ( LF ; high
estrogen ) ] on vulnerability to acute
hyperglycemia - induced changes in arterial stiffness is unknown . -
pubmed
These results suggest that premenopausal
women may experience protection from acute
hyperglycemia - induced
increases in arterial stiffness . -
pubmed
Here , we briefly describe the progress made towards a vaccine against
Plasmodium falciparum , the most pathogenic of the
malaria parasite species to infect
humans . -
pubmed
Single - agent
ibrutinib in RESONATE-2 and RESONATE versus treatments in the real - world PHEDRA databases for
patients with
chronic lymphocytic leukemia . -
pubmed
After analyzing treatment patterns in
chronic lymphocytic leukemia (
CLL ) ( objective 1 ) , we investigated the relative effectiveness of
ibrutinib versus other commonly used treatments ( objective 2 ) in
patients with treatment - naive and relapsed / refractory
CLL , comparing patient - level data from two randomized registration trials with two real - world databases . -
pubmed
Grade > = 3
adverse drug reactions ( ADRs ) were reported in 61.7 % of the
patients . -
pubmed
Carcinoma of the breast ( 21.3 % ) , lung ( 12.9 % ) , and gastrointestinal tract ( GIT ) ( 35.8 % ) accounted for the majority of the
patients , and 44.7 % of the
patients had metastatic disease . -
pubmed
RESULTS :
Anemia was observed in 49.7 % of
patients with
cancer and in 11.9 % of healthy controls ( p < 0.001 ) . -
pubmed
Having
metastatic disease , and having
nutritional deficiencies as
iron ,
B12 , and
folate were evaluated as possible risk factors for
anemia in
patients with newly diagnosed
cancer , whereas
cancer with GIT localization and previous history of
tumor surgery were not . -
pubmed
Quercetin - Mediated Apoptosis and Cellular Senescence in
Human Colon Cancer . -
pubmed
BACKGROUND :
Quercetin is a
flavonol from the
flavonoid group of
polyphenols which positively affects
human health due to its anti -
cancer , anti - inflammatory , anti - microbial and cardioprotective effects . -
pubmed
Further , MycoAuNPs showed potential growth of
tumor in
tumor - bearing
mice models . -
pubmed
Further attention placed on potential sex differences in
epilepsies , comorbidities , and drug effects will enhance therapeutic options and efficacy for all
patients with
epilepsy . -
pubmed
In this review , we discuss sex differences in types of
epilepsies , associated comorbidities , pathophysiological mechanisms , and antiepileptic drug efficacy in both clinical
patient populations and preclinical animal models . -
pubmed
The lifestyle and lowered daily activity of elderly
adults , along with the
deficit of motor and cognitive brain functions , might lead to the developed ambidexterity , i.e. -
pubmed
We reviewed pathological findings and clinical breast MRI examinations of 169
patients with invasive
BC who were evaluated at the Hotel - Dieu de France Hospital in 2009 - 2015 . -
pubmed
Myositis induced by
durvalumab in a
patient with
non - small cell lung cancer : A case report . -
pubmed
A 60 - year - old
man with
stage IIIA lung adenocarcinoma was treated with
durvalumab after concurrent chemoradiation therapy . -
pubmed
Centruroides margaritatus scorpion stings are common in Colombia . -
pubmed
Vision - related quality of life in
patients with a history of
congenital glaucoma . -
pubmed
PURPOSE : To assess the vision - related quality of life in adult
patients with a history of primary
congenital glaucoma . -
pubmed
METHODS : In a cross - sectional hospital - based study eligible
patients with a history of primary
congenital glaucoma aged more than 18 were recruited in the study . -
pubmed
Patients with
secondary glaucoma and monocular
patients were excluded . -
pubmed
RESULTS : A total of 23
congenital glaucoma patients have enrolled in the study . -
pubmed
OBJECTIVES : This study aims to investigate the effect of radial extracorporeal
shock wave therapy ( rESWT ) treatment in the prevention of
epidural fibrosis after laminectomy in
rats . -
pubmed
CONCLUSION : The rESWT application immediately after surgery is effective in preventing epidural
fibrosis after laminectomy in
rats . -
pubmed
Wastewater - based surveillance of the
severe acute respiratory syndrome coronavirus 2 (
SARS - CoV-2 ) is used to monitor the population - level prevalence of the
COVID-19 disease . -
pubmed
The methods and criteria for testing for synergy were compared with use of 22
strains of
Klebsiella pneumoniae and a combination of
cephalothin and
gentamicin . -
pubmed
The indications , investigations and techniques for treating
patients with
chyluria are presented . -
pubmed
A case of
thymic carcinosarcoma associated with a
spindle cell thymoma in a 71 - year - old
woman is reported . -
pubmed
The following analyses , which examined whether the timing of the first breast milk substitute to which the infant was exposed differed between
diabetic and control subjects , were conducted for exposure to any breast milk substitute and to breast milk substitutes that were
cow 's milk based . -
pubmed
In whites , age at exposure to any breast milk substitutes and
cow 's milk - based substitutes were similar between
diabetic and control subjects . -
pubmed
In blacks , the first exposure to breast milk substitutes occurred significantly earlier for any substitute ( 5.1 vs. 11.9 wk , P = 0.02 ) and marginally earlier for
cow 's milk - based substitutes ( 3.9 vs. 8.5 wk , P = 0.07 ) in
diabetic subjects compared with control subjects . -
pubmed
Effects of exercise test on plasma markers of an activation of coagulation and/or fibrinolysis in
patients with symptomatic or silent
myocardial ischemia . -
pubmed
Symptoms and scintigrams allowed to define three groups of
patients : those showing no
ischemia ( n = 79 ) and those with symptomatic ( n = 8) or silent
myocardial ischemia ( n = 13 ) . -
pubmed
On the other hand , the F1 + 2 levels were slightly albeit significantly higher in the
patients without
ischemia than in the
patients with symptomatic or silent
ischemia . -
pubmed
When
P19 mouse embryonal carcinoma cells are grown in a serum - free N2 medium on surfaces of tissue culture plastic , they die within two days . -
pubmed
[ Diagnosis and therapeutic tactics in destructive
cholecystitis in middle - aged and elderly
patients ] . -
pubmed
Differential
tumor regression in
patients with bilobar hepatic
metastases and dual arterial supply : evidence supporting the advantage of intra - arterial over intravenous route of drug delivery . -
pubmed
Two
patients with bilobar
liver metastases were characterized by dual arterial blood supply to the liver . -
pubmed
Treatment of both
patients by the administration of chemotherapy , selectively via the arterial branches supplying the respective hepatic lobes bearing the
metastases , resulted in differential
tumor regression / progression . -
pubmed
When 6 - 7 months old ,
MSG - treated
rats presented reduced body , adrenal and pituitary weight ,
obesity ,
atrophy of the optic nerve and damage of the arcuate nuclei ( ARN ) of the hypothalamus . -
pubmed
These results suggest that the ARN may be involved in the regulation of the pituitary - adrenal axis , although the abnormalities observed in the
MSG syndrome partially differ from those in
rats with
hippocampal damage , previously studied in our laboratory . -
pubmed
A 30 week gestation infant developed
necrotising enterocolitis associated with
Clostridium perfringens septicaemia at 3 weeks of age . -
pubmed
In a 59 - year - old patient with
Crohn ' s disease ,
tricuspid valve endocarditis caused by
candida albicans was observed . -
pubmed
We have applied this technique of profound
hypothermia and
circulatory arrest in three other adult
patients in whom conventional techniques would not allow safe and adequate complete repair of acquired
intra - cardiac defects . -
pubmed
The second
patient underwent valve replacement during a period of
circulatory arrest because of extensive
calcification of the entire ascending aorta and transverse aortic arch . -
pubmed
The third
patient was a 54 - year - old female and had a large
patent ductus arteriosus with a 3:1 left - to - right shunt as well as significant
aortic and mitral valve disease . -
pubmed
All three
patients recovered uneventfully with no evidence of any significant
neurologic defect . -
pubmed
Very long chain
fatty acid (
VLCFA ) beta - oxidation was compared in homogenates and subcellular fractions of cultured skin fibroblasts from normal
individuals and from
Zellweger patients who show greatly reduced numbers of peroxisomes in their tissues . -
pubmed
Thus the relationship of
pseudomyotonia to increasing oxidative activity in the hind limb muscles of
dystrophic animals was evident . -
pubmed
The second
patient experienced
conjunctival pruritus after each of several doses of
zomepirac before emergency department presentation with acute
dyspnea and
urticaria . -
pubmed
The third
patient had been admitted previously with a diagnosis of rule out
myocardial infarction , which in retrospect was probably a
zomepirac reaction . -
pubmed
[ Serum and liquor immunoelectrophoresis in normal subjects and in
patients affected by degenerative and
spondylosic myelopathies ] . -
pubmed
[ The use of
aminokrovin in the treatment of
children suffering from
Botkin ' s disease ] . -
pubmed
Besides , antibody to
tick - borne encephalitis virus ,
Powassan virus and both viruses simultaneously was found in patients with progredient forms of
tick - borne encephalitis and in subjects with the history of tick attachment . -
pubmed
The
injury was caused by acid in 57
patients ( 33 % ) . -
pubmed
Fifty three
patients mostly with alkaline and acid
burns were treated with prolonged irrigation with one liter of physiological saline using intravenous delivery system during 1 - 2 hours . -
pubmed
Collagen metabolism was studied in
patients with
viral hepatitis ,
chronic hepatic disorders as well as under experimental conditions , in
rats with
carbon tetrachloride - induced
hepatic fibrosis . -
pubmed
Islet cell transplantation in
diabetic dogs : studies of graft function and storage . -
pubmed
Islet cell autotransplants rendered such
animals metabolically normal apart from persisting
impairment of glucose tolerance . -
pubmed
[ Individual variation and mechanism of
kanamycin ototoxicity in
rabbits ( author 's transl ) ] . -
pubmed
93
patients who had been irradiated before or after surgery of a
hypernephroma were checked up in order to find secondary diseases . -
pubmed
Sixteen
patients had died , three of them because of therapy effects , six because of
tumor recurrences and seven because of other factors . -
pubmed
Two
patients had local
recurrences . -
pubmed
Ocular Toxoplasmosis is usually considered a
recurrence of a
congenital infection , and this fact enhances the importance of prevention in pregnant women in order to avoid transplacental passage of free forms of the parasite
Toxoplasma gondii . -
pubmed
All of the Tg(MHu2 M )
mice developed
neurologic disease approximately 200 days after inoculation with brain homogenates from three
patients dying of
Creutzfeldt - Jakob disease (
CJD ) . -
pubmed
About 10 % of Tg(HuPrP )
mice expressing HuPrP and non - Tg
mice developed
neurologic disease & gt ; 500 days after inoculation with
CJD prions . -
pubmed
Diagnosis , prevention , and treatment of Hu
prion diseases should be facilitated by Tg(MHu2 M )
mice . -
pubmed
Although control of any degree of
hypertension with any antihypertensive drug will slow the progression of
renal failure from any cause ,
captopril , an
angiotensin - converting enzyme ( ACE ) inhibitor , has been shown to slow progressive
renal failure in
patients with
insulin - dependent diabetes mellitus to a greater degree than that expected from only its antihypertensive effect . -
pubmed
An analysis of results of 758
IVF cases provides preliminary evidence to show that there is a close association between
human in vitro fertilization rate and subsequent embryo viability following replacement . -
pubmed
In contrast , SD
hamsters that were given daily injections of the EAA agonist ,
N - methyl - D , L - aspartate (
NMA ; 50 mg / kg
body weight , s.c . ) -
pubmed
BACKGROUND : Uncontrolled
increase in intracranial pressure is the most significant cause of mortality in
patients with severe
traumatic brain lesions , and the efficacy of common non - surgical treatments has been questioned . -
pubmed
METHODS : In a
porcine model of
intracranial hypertension induced with two epidural balloons to a level of 26 - 28 mmHg , 18
animals were randomized into three groups receiving 0.1 , 0.3 , and 3.0 mg.kg-1.h-1
indomethacin , respectively , as an infusion during 80 min . -
pubmed
This was accompanied by signs of
cerebral ischemia when
indomethacin was used in a dose that has previously been suggested for the treatment of increased intracranial pressure in
patients . -
pubmed
Recurrent
hypoglycaemia associated with first and second trimester
insulin sensitivity in a
patient with
insulin - dependent diabetes . -
pubmed
A 35 - year - old
insulin - dependent diabetic woman presented at 8 weeks gestation with multiple severe
hypoglycaemic episodes occurring during the day and night without warning . -
pubmed
[ The functional activity of the lymphocyte subpopulations in
patients with
schizophrenia and
schizoaffective psychosis ] . -
pubmed
The increase of cytotoxic NK activity was seen in
patients with
schizoaffective psychosis after the treatment while such alterations in
schizophrenic patients were absent . -
pubmed
To develop an improved treatment schedule for
osteoporosis , a study was undertaken in 100 postmenopausal
women using a modified ADFR 90 - day cyclical regimen with
etidronate . -
pubmed
In addition ,
coinfection either with
HPV-6 and -16 or with
HPV-6 and -18 was detected in 20 cases ( 33.3 % of
HPV DNA - positive cases ) . -
pubmed
Although combination chemotherapy regimens may prolong survival for selected
patients with metastatic
breast cancer , few , if any , are cured . -
pubmed
Imaging investigations and other findings observed in a term
infant with a multicentric
hepatic hemangioendothelioma , admitted to the Intensive Care Unit at the age of 13 days because of non specified feeding difficulties and
dyspnoea , are presented . -
pubmed
The pattern of
fever response to empiric anti -
tuberculosis therapy in patients with
tuberculosis (
TB ) and
human immunodeficiency virus ( HIV ) infection , and the relationship between
fever response patterns and anti - TB drug susceptibility profiles of
Mycobacterium tuberculosis isolates are rarely described . -
pubmed
Drug susceptibility data were available for 22
patients with
TB . -
pubmed
138
patients with
end - stage kidney disease and 118
patients with
end - stage liver disease were included in an observational cohort study regarding their quality of life . -
pubmed
An initial rhythm of pulseless electrical activity was present in 50.1 % of the
patients ,
ventricular fibrillation /
ventricular tachycardia in 34.2 % , and
asystole in 15.7 % . -
pubmed
METHODS : Two hundred and ninety - nine
Type 2 diabetic patients were investigated for smoking habits by unstructured questionnaire , breath CO , and urinary ratio . -
pubmed
Striatal oxidative damage parallels the expression of a neurological phenotype in
mice transgenic for the mutation of
Huntington ' s disease . -
pubmed
We examined the degree of oxidative damage to the brain of
mice transgenic for the mutation responsible for
Huntington ' s disease . -
pubmed
Within a multicenter study 56
patients admitted for
chest pain ( & lt ; 12 h ) and with a non - diagnostic 12 - lead ECG on admission and a VCG recording were included . -
pubmed
Successful cannulation was achieved in six out of 10
patients with
haematoma complicating the procedure in two patients . -
pubmed
OBJECTIVE : To describe the clinical findings in
patients with acute idiopathic
blind spot enlargement (
AIBSE ) . -
pubmed
METHODS : Medical record review of 27
patients with
AIBSE ( without sufficient
optic nerve head swelling to cause
blind spot enlargement ) seen in 2 academic neuro - ophthalmology units . -
pubmed
All
patients had enlarged blind
spots of variable size and density . -
pubmed
Twelve of the 13
patients who underwent
fluorescein angiography had optic disc staining and 5 had
retinal pigment epithelial lesions with late staining . -
pubmed
Six
patients experienced
recurrence . -
pubmed
Unlike
patients with multiple evanescent
white dot syndrome , recovery of visual field did not occur in
patients with
AIBSE . -
pubmed
Changes in these domains lead to a reduced functional ability of the
AD patient which results , inevitably , in an increasing dependency of the patient on their carer . -
pubmed
Thus , a compromised quality of life for both the
patient with
AD and the carer ensues . -
pubmed
The abnormality in cholinergic neurotransmission , by contributing to both the
cognitive impairment and possibly the behavioural disturbances of
AD patients , has attracted particularly intense scientific attention . -
pubmed
Evidence for the involvement of a cholinergic dimension to the behavioural changes of
AD includes the following : the induction of
AD - like behaviours in normal
individuals by administration of anticholinergic drugs ; the exaggeration of behavioural disturbances in
AD patients by anticholinergic agents ; the correlation of the distribution of cholinergic deficits of
AD with regions that are relevant to the observed behaviours , i.e. -
pubmed
RESULTS : All
patients , including some with very severe
airway anomalies , were uneventfully intubated using the regimen we have described . -
pubmed
The onset of
hypoventilation was recognized in
patients and appropriately treated by adjusting the narcotic dose . -
pubmed
Coughing occurred only in 5
patients and 37 out of 40
patients had no recall that intubation had occurred . -
pubmed
A 92 - year - old
woman with mucinous
adenocarcinoma of Bartholin gland with
metastasis to the right inguinal lymph node was treated with radiation therapy alone . -
pubmed
Despite intensive radiation therapy , the
tumor was locally recurrent and the
patient died 10 months after radiation therapy . -
pubmed
UNLABELLED : Malfunction of vascular access is one of the most frequent causes of morbidity and mortality in hemodialysis
patients (
HD ) . -
pubmed
Early diagnosis makes possible the most frequent vascular access ( VA ) used in
HD patients . -
pubmed
Using the Transonic HD01 monitor , we studied vascular access in 45
patients in
HD older than 65 years , and compared them with 47
patients who were younger than 65 years . -
pubmed
Ammonia toxicity as a criterion for the evaluation of larval quality in the prawn
Macrobrachium rosenbergii . -
pubmed
CRRT is most commonly indicated for hemodynamically unstable
patients who have
acute renal failure and a narrow margin of tolerance for the rapid fluid shifts associated with traditional dialysis . -
pubmed
and the agent of
human granulocytic ehrlichiosis in Colorado . -
pubmed
Previous work demonstrated that
Ixodes spinipalpis ticks maintained an enzootic cycle of
Borrelia bissettii and the agent of
human granulocytic ehrlichiosis (
aoHGE ) within woodrats (
Neotoma mexicana ) and
deer mice (
Peromyscus maniculatus ) in northern Colorado ( USA ) . -
pubmed
METHODS : One hundred twenty - three
patients from 98 families with a diagnosis of
Hallervorden - Spatz syndrome were classified on the basis of clinical assessment as having classic disease ( characterized by early onset with rapid progression ) or atypical disease ( later onset with slow progression ) . -
pubmed
Genetic analysis of longitudinal trajectory of clinical
mastitis in first - lactation Norwegian
cattle . -
pubmed
[ Contribution of electron microscopy to the study of
human hepatic steatosis ] . -
pubmed
METHODS : The authors studied 18 female
patients who underwent either transurethral resection ( n = 2 ) or radical cystectomy ( n = 16 ) for high - grade
muscle - invasive urothelial carcinoma of the urinary bladder . -
pubmed
OBJECTIVE : This histomorphometric study compared the open and prematurely fused side of the coronal suture in
subjects with
unilateral coronal synostosis (
UCS ) . -
pubmed
METHODS : Sutures and parasutural bone were obtained from seven
subjects with nonsyndromic
UCS during operative correction at 3 to 24 months of age . -
pubmed
The primary causes of
squamous cell carcinoma of the esophagus are
tobacco use and
alcohol consumption , whereas the main risk factors for
adenocarcinoma of the esophagus are
gastroesophageal reflux disease and
obesity . -
pubmed
The aim of the present study was to compare
patient survival ,
death - censored technique survival and
peritonitis - free survival between patients initiating PD after failed renal allografts and those after failed native kidneys . -
pubmed
On multivariate analysis ,
PD patients with failed kidney transplants had comparable
patient mortality [ weighted hazards ratio ( HR ) 1.09 , 95 % confidence interval ( CI ) 0.81 - 1.45 , P = 0.582 ] ,
death - censored technique failure ( adjusted HR 0.91 , 95 % CI 0.75 - 1.10 , P = 0.315 ) and
peritonitis - free survival ( adjusted HR 0.92 , 95 % CI 0.72 - 1.16 , P = 0.444 ) with those
PD patients who had failed native kidneys . -
pubmed
Traumatic internal carotid artery dissection is a serious condition that may cause
ischemic stroke in young
patients . -
pubmed
The
CH ( 2 ) Cl ( 2 )/ CH ( 3 ) OH extract of
Kalanchoe crenata significantly increased the latency period in
seizures induced by
PTZ and significantly reduced the duration of
seizures induced by the three convulsant agents . -
pubmed
The assay has manifold applications in fundamental research for DNA damage and repair , in
genotoxicity testing of novel chemicals and pharmaceuticals , environmental biomonitoring , and
human population monitoring . -
pubmed
We used pulsed - field gel electrophoresis analysis and genotyping to compare clinical isolates of
Bordetella pertussis recovered since the early 1990s in Finland and France , 2 countries with similar histories of long - term mass vaccination with whole - cell
pertussis vaccines . -
pubmed
It has been proposed that
schizophrenia results from an environmental insult in genetically predisposed
individuals . -
pubmed
It outlines how three students , who formed a collegial group , prepared for the experience , completed and documented assigned visits , summarized outcomes , and discussed some implications for ministry with terminally ill
comatose patients . -
pubmed
Bilateral tibial
chronic osteomyelitis due to
Pantoea agglomerans in a patient with
sickle cell disease . -
pubmed
In
mammals , QA intoxication is characterized by trembling , shaking , excitation , and
convulsion . -
pubmed
A total of 185
patients with localized
esophageal cancer were included , 89 undergoing multimodal therapy and 96 surgery alone . -
pubmed
PURPOSE : This study was designed to evaluate the pharmacologic and biological properties of a
paclitaxel - hyaluronan bioconjugate ( ONCOFID - P ) against
IGROV-1 and
OVCAR-3 human ovarian cancer xenografts following i.p . -
pubmed
Female
severe combined immunodeficiency mice implanted with
ovarian cancer cells underwent treatment with
ONCOFID - P or free
paclitaxel starting from day 7 or 14 after
tumor injection , and survivals were compared . -
pubmed
Intraperitoneal treatment of
tumor - bearing
mice with the bioconjugate revealed that
ONCOFID - P exerted a relevant increase in therapeutic activity compared with free drug . -
pubmed
Between July 2003 and July 2006 , we treated 60
patients ( 20
men and 40
women , mean age 26 years ) who suffer from
palmar hyperhidrosis by endoscopic thoracic sympathectomy ( ETS ) . -
pubmed
METHODS : Clinically depressed older
adults with MRI - defined
SID ( n = 70 ) and
depressed elders without
SID ( n = 75 ) were compared on neuropsychological performance ,
depression symptoms , and medical burden . -
pubmed
CONCLUSIONS : Although auditory working memory span and nonverbal memory appear to be specifically associated with the ischemic pathology that defines
SID , the typical
individual with
SID is also likely to have a broader profile of neuropsychological deficits than those without
SID because they are typically older and have specific
depression symptoms that predispose them to
compromised neurocognitive performance . -
pubmed
Klebsiella oxytoca as a cause of
equine abortion -- short communication . -
pubmed
Effects of
selenium and low levels of lead on
mammary tumor development and growth in
MMTV - infected female
mice . -
pubmed
Selenium (
Se ) has been demonstrated in previous studies to inhibit mammary
tumorigenesis in
C3H mice infected with the
murine mammary tumorvirus ,
MMTV . -
pubmed
In the experimental groups , the
Pb - exposed
mice on the 0.15 ppm
Se feed developed signs of chronic
Pb toxicity as evidenced by diminished
weight gain that persisted up to the age of 10 months , during which period the animals remained
tumor - free . -
pubmed
In the group of
mice on the 0.65 ppm
Se feed , the toxic effects of
Pb were diminished , as evidenced by the normal
weight gains during the first 10 months but with concomitant physiological inactivation of
Se , causing 82.6 % of the
mice to develop
tumors , with the first
tumor to appear at the age of 5 months , 7 months earlier than in the
Pb - unexposed controls . -
pubmed
Direct evidence for the interactions of
Pb with
Se were obtained by determinations of the two elements in the livers , kidneys , and hair of
tumor - free and
tumor - bearing
mice . -
pubmed
However , the exposure of the
mice to
Pb in the water also altered the levels of
Zn ,
Cu ,
Fe , and
Cr in the organs and tissues , more so in
tumor - bearing than
tumor - free
animals . -
pubmed
In Mexico ,
Nocardia brasiliensis is the main causative agent of
mycetoma , producing about 86 % of the cases ; the gold standard for the therapy of
mycetoma by
N. - pubmed
In the present work , we evaluated the in vivo effect of
DA-7867 , an experimental
oxazolidinone , on the development of experimental
mycetomas by
N. - pubmed
As a control we utilized
linezolid at 25 mg / kg , a compound active in
murine and
human infections , three times a day . -
pubmed
Since
oxazolidinones seem to be active against a wide spectrum of actinobacteria , it is possible they could be used in
human cases of
mycetoma by other actinomycetales , such as
Streptomyces somaliensis , highly prevalent in Sudan , or
Actinomadura madurae and
A. - pubmed
The molecular mechanism of
dexamethasone - mediated effect on the
blood - brain tumor barrier permeability in a
rat brain tumor model . -
pubmed
METHODS : DNA was extracted from peripheral blood leukocytes of 49 euthymic
bipolar patients and 27 matched healthy controls . -
pubmed
RESULTS : Leukocyte global DNA methylation did not differ between
bipolar patients [ 62.3%+/-18.0 ( S.D ) ] and control subjects ( 63.9%+/-14.6 ) , p=0.70 . -
pubmed
Bipolar patients ' plasma
homocysteine levels ( 11.5 microM+/-4.8 ) did not differ from those of healthy controls ( 11.4+/-2.9 ) , p=0.92 . -
pubmed
Risperidone : a review of efficacy studies in
adolescents with
schizophrenia . -
pubmed
To reveal the molecular and genetic mechanism of fertility restoration in Ogura
male sterility in
Japanese wild radish (
Raphanus sativus var . - pubmed
RESULTS : Forty - two
patients with advanced
solid tumors , including 16
NSCLC , were treated . -
pubmed
Four
patients with
NSCLC remained on therapy for 9 , 16 , 16 , and 22 cycles . -
pubmed
Subsequent elimination of
brucellosis in commercial
swine resulted in a decrease in
B. - pubmed
Currently , swine - associated
brucellosis in
humans in the United States is predominantly associated with exposure to infected feral
swine ( i.e. -
pubmed
Hypomethylating agent induction therapy followed by hematopoietic cell transplantation is feasible in
patients with
myelodysplastic syndromes . -
pubmed
[ Engineering and metabolic characteristics of a
Clostridium tyrobutyricum strain ] . -
pubmed
This study aimed to determine the effectiveness of a
depression training program on practitioners ' confidence , perceived barriers , and their likelihood of responding to
depression in
patients with
vision impairment . -
pubmed
CONCLUSIONS : This preliminary study found that a brief training program is effective in increasing practitioners ' ability to respond to
depression in
patients with
vision impairment . -
pubmed
Recently , we showed that an active
mouse CMV ( mCMV ) infection in nonpregnant
mice increased endothelial - dependent vasodilation in isolated mesenteric and uterine arteries . -
pubmed
Thus
CMV infection affects the contribution of
NO differently in endothelial - dependent vasodilation in pregnant compared with nonpregnant
mice and also in the mesenteric compared with the uterine vascular bed . -
pubmed
A
patient with multiple synchronous
gliomas of distinctly different grades and correlative radiographic findings . -
pubmed
We present a
patient with bi - hemispheric , noncontiguous , low- and
high - grade gliomas proven by biopsy . -
pubmed
CASE DESCRIPTION : A 64 - year - old
female presented to the hospital with
confusion ,
disorientation and
retrograde amnesia after an unwitnessed fall . -
pubmed
We found that standard and large - capacity forceps used with standard upper endoscopes produced biopsy samples at least as adequate as those obtained with jumbo forceps and therapeutic endoscopes in
patients with
BE . -
pubmed
injection of BBL into
rats induced a dose - dependent paw
edema , an effect that occurred via
carbohydrate site interaction and was significantly reduced by
L - NAME , suggesting an important participation of
nitric oxide in the late phase of the
edema . -
pubmed
RESULTS : We reviewed the literature and provided several practical examples of common cross - sectional imaging findings in
patients with
pancreatic neoplasms . -
pubmed
The authors discuss the usefulness of therapeutic
hypothermia for neuroprotection in
patients with hypoxic
cerebral damage . -
pubmed
Recently , the American Heart Association and European Resuscitation Council recommended the use of mild
hypothermia ( 32 - 34 degrees C ) in adult
patients after
ventricular fibrillation . -
pubmed
Randomized clinical trials in
newborns with
hypoxic ischemic encephalopathy confirm improved neurological outcomes and survival at 18 months of age with therapeutic
hypothermia . -
pubmed
They conclude that mild
hypothermia can be regarded as a useful therapy in adult
patients after VF
cardiac arrest , and in neonates with
hypoxic cerebral brain damage . -
pubmed
Similar responses were observed after intravenous administration in spontaneously
hypertensive rats . -
pubmed
MATERIAL AND METHODS : Thirty - five needle biopsies from
patients with
prostate cancer (
PC ) aged 60 to 75 years were investigated . -
pubmed
Salidroside , a
phenol glycoside of
plant origin , has been documented to possess a broad spectrum of pharmacological properties , including protective effects against neuronal
death induced by different insults . -
pubmed
To provide further insights into the neuroprotective functions peculiar to
salidroside , this study used primary cultured cortical neurons of
rats as a cell model to examine whether
salidroside was able to prevent against cell damage after exposure to
cobalt chloride (
CoCl ( 2 ) ) , a
hypoxia - inducing agent . -
pubmed
Keratotic lesions on the nipples and areolae of a 62 - year - old
man . -
pubmed
An in vit ro model utilizing
human cervical cells and papillomaviruses (
HPV ) that mimics
human cervical cancer has been developed . -
pubmed
Acquisition of immortality after
HPV-16 transfection was associated with
aneuploidy , structural changes of chromosomes 8 , 10 , 17 , 19 , 20 , and 21 , as well as proto - oncogene alterations . -
pubmed
RESULTS : One hundred and ninety
patients with apparent early - stage
EOC undergoing primary surgical staging met criteria for inclusion . -
pubmed
No
patients with
mucinous cancers ( n=29 ) had lymph node
metastases . -
pubmed
CONCLUSIONS : Complete surgical staging in
EOC patients with gross
disease confined to the ovaries and pelvis should include bilateral pelvic and paraaortic lymphadenectomy . -
pubmed
Even in
patients with unilateral lesions , lymph node
metastases are commonly bilateral . -
pubmed
This information may be helpful in counseling
patients presenting for consideration of re - staging after unexpected findings of
malignancy . -
pubmed
Dengue virus (
DENV ) is the causative agent of the most prevalent
arthropod - borne viral disease , thus representing a significant global health burden . -
pubmed
A 65 - year - old
man with
chronic renal failure due to
polycystic kidneys and under hemodialysis treatment 3 times a week for 2 years was admitted to our hospital because of
anemia . -
pubmed
The experimental groups consisted of 20
gingivitis patients and 20
periodontitis patients and the control group had healthy subjects ( 20 samples ) . -
pubmed
Patients with
periodontal disease were under conventional periodontal treatment . -
pubmed
Tumor hypoxia is known to be associated with radio / chemo - resistance and
metastasis that eventually lead to
cancer progression contributing to poor prognosis in
cancer patients . -
pubmed
METHODS : Eleven male
adults with unilateral
midportion Achilles tendinopathy and nine control male
adults without
tendinopathy participated in the research . -
pubmed
RESULTS : We observed maximum
paralysis ( & gt;=70 % ) at 2 weeks , and the rate of recovery varied widely ranging from 2 to 5 months , with two
patients continuing to exhibit reduced contraction at 24 weeks . -
pubmed
[ Effectiveness of a stretching program on
anxiety levels of
workers in a logistic platform : a randomized controlled study ] . -
pubmed
OBJECTIVE : To study the influence of a short programme of stretching exercises on
anxiety levels of
workers in a Spanish logistic company . -
pubmed
The rate of
CRS in this cohort of 196
patients was 10.2 % ( n=20 ) , of which 15 % ( n=3 ) developed
ARS , although none had symptoms of
CRS at the time of surgery ; one had undergone previous
sinus surgery . -
pubmed
Presenting symptoms of
ARS included facial
pain ,
tenderness over the affected
sinus , and nasal discharge ; all
patients responded to oral antibiotic therapy . -
pubmed
A constant turnover of variant - specific
amino acid change was observed , particularly within the antigenic epitopes A , C and E. In conclusion , this study has characterized the
NoV strains in circulation in Singapore between 2004 and 2011 . -
pubmed
Clinical outcome post - progression to first - line triplet chemotherapy ( CT ) plus
bevacizumab ( FIr - B / FOx ) was evaluated in metastatic
colorectal cancer (
MCRC )
patients ( pts ) . -
pubmed
Almost half the
patients on peritoneal dialysis are
diabetic and glycemic control is essential to improve both
patient and technique survival . -
pubmed
METHODS :
Mice were anesthetized and then infected intranasally by dropping 0.05 mL of
influenza virus suspension ( 4xLD50 ;) except normal group . -
pubmed
However , inactivated vaccines are based on
TBEV strains of the heterologous Far Eastern or the European subtypes isolated 40 - 77 years ago . -
pubmed
To analyze the efficacy of the available vaccines against currently prevailing
TBEV isolates of the Siberian subtype ,
mice were immunized subcutaneously three times ( one group per each vaccine ) . -
pubmed
BACKGROUND :
Children with specific
language impairments carry a high risk for the development of
reading and writing disorders . -
pubmed
We reviewed prospectively collected data in a consecutive series of 193
patients with
laryngeal dystonia who were seen at St. Vincent 's Hospital between 1991 and 2011 . -
pubmed
Patients with
adductor SD ,
stridor ,
extra - laryngeal dystonia and male
patients had relatively better treatment outcomes . -
pubmed
Cross - cultural adaptation , reliability , internal consistency and validation of the Hand Function Sort ( HFS ) for French speaking
patients with
upper limb complaints . -
pubmed
METHODS : 150
patients with various
upper limbs impairments were recruited in a rehabilitation center . -
pubmed
However , in debilitated people with
immune deficiencies ,
Candida can cause serious invasive
infections with high mortality . -
pubmed
Even though some critical points about the BMSC - based therapy model still need clarification , we hope to develop more reliable pharmacological or biotechnical strategies utilizing the stem cell for the eventual treatment of
humans with
AKI , based on these studies and the understanding of mechanism of renal protection by BMSCs . -
pubmed
Postoperative complications were seen in 16 % ( 7
patients ) . -
pubmed
These 7
patients had the following complications :
wound dehiscence ( 7 % [ n = 3 ] ) ,
osteomyelitis ( 7 % [ n = 3 ] ) ,
abscess development ( 4 % [ n = 2 ] ) ,
bone necrosis ( 2 % [ n = 1 ] ) , and severe
nonocclusion ( 2 % [ n = 1 ] ) . -
pubmed
Dietary supplementation with
docosahexanoic acid (
DHA ) increases red blood cell membrane flexibility in
mice with
sickle cell disease . -
pubmed
Humans and
mice with
sickle cell disease (
SCD ) have rigid red blood cells ( RBCs ) . -
pubmed
Drug induced
hepatotoxicity was observed in the older
patients . -
pubmed
CONCLUSION : The study showed that the risk of development of drug - induced
hepatotoxicity following treatment with first line anti -
tuberculosis treatment increased with the age of the
patient . -
pubmed
Here , we investigated the antitumorigenic effects of
curcumin and
3 acetyl-11 - keto - beta - boswellic acid (
AKBA ) on modulation of specific
cancer - related miRNAs in
colorectal cancer cells and validated their protective effects in vivo using a xenograft
mouse model . -
pubmed
Furthermore , we demonstrated in a
mouse xenograft model that both
curcumin and
AKBA treatments suppressed
tumor growth , which corresponded with alterations in the expression of miR-34a and miR-27a , consistent with our in vitro findings . -
pubmed
We report the case of an
infant diagnosed as
cutaneous mastocytosis and
seasonal allergies . -
pubmed
METHODS : Three eyes of 3
patients with
pseudophakic bullous keratopathy underwent the procedure in this single - center , prospective interventional series . -
pubmed
Our results are generally comparable to previous PM2.5 and dLAN reports conducted on
mice and implicate PM2.5 and
dLAN as potential factors contributing to
depression and
anxiety . -
pubmed
Immunostimulant and chemoprotective effect of vivartana , a polyherbal formulation against
cyclophosphamide induced
toxicity in
Swiss albino mice . -
pubmed
Dengue has spread to new geographic areas affecting both
children and adults , and it has become a global threat . -
pubmed
Rituximab - induced
interstitial lung disease in a
patient with
follicular lymphoma : A rare case report . -
pubmed
Patient developed exertional
dyspnea and
dry cough after the fourth cycle of
rituximab - based chemotherapy . -
pubmed
[ Pathogenesis and prevention of secondary
thromboses and
thromboembolic complications in
patients with endured lower limb
deep vein thrombosis ] . -
pubmed
The study included a total of 84
patients presenting with lower limb
deep vein thrombosis . -
pubmed
The
patients of the Study Group ( n=44 ) were examined for
thrombophilic states , revealing of which was followed by prescribing specific lifelong therapy aimed at correction of the alterations revealed . -
pubmed
The Study Group
patients demonstrated less
relapses of
deep vein thromboses as compared with the Control Group
patients . -
pubmed
A conclusion was drawn on the necessity of carrying out further studies aimed at altering the recommended therapeutic regimen for
patients in the remote period after sustained
deep vein thrombosis . -
pubmed
The protective effects of
carvacrol and
thymol against
paracetamol - induced
toxicity on
human hepatocellular carcinoma cell lines (
HepG2 ) . -
pubmed
These findings provide novel insights into a possible molecular mechanism by which childhood maltreatment heightens the risk for
relapse in
cocaine - dependent
individuals . -
pubmed
Our results suggest that , as in
patients , chronic
pelvic pain is a consequence of
prostate inflammation . -
pubmed
Intraoperative
Tension Pneumothorax in a
Patient With Remote
Trauma and Previous Tracheostomy . -
pubmed
Many
trauma patients present with a combination of
cranial and thoracic injury . -
pubmed
We report a case of a 25 - year - old
patient with remote
thoracic trauma , who developed an intraoperative
tension pneumothorax and
hemodynamic instability while undergoing an elective cranioplasty . -
pubmed
The intraoperative
patient assessment was made even more challenging by unexpected massive
blood loss from the surgical site . -
pubmed
Timely recognition and management of intraoperative
pneumothorax along with adequate blood replacement stabilized the
patient and helped avoid an unfavorable outcome . -
pubmed
This case highlights the risks of intraoperative
pneumothorax in
trauma patients , which may develop even months after
injury . -
pubmed
Although Sapovirus ( Caliciviridae ) has been accepted as one of the causes of
acute gastroenteritis worldwide , little is known about the genetic characteristics of the whole genome of sapoviruses in China , especially those that infect
humans . -
pubmed
In this review , we evaluate the existing body of evidence and offer an approach to the management of
patients with
ARAS in light of the current literature . -
pubmed
7
patients died within 30 days ; none of the
deaths were recorded as procedure - related . -
pubmed
Capnocytophaga canimorsus is a dog oral commensal that causes rare but severe
infections in
humans . -
pubmed
We describe nine different serovars ( A to I ) , and this serotyping scheme allowed typing of 25/25 isolates from
human infections but only 18/52 isolates from dog mouths , indicating that the repertoire of capsules in the species is vast . -
pubmed
Capsular serotyping would thus allow identification of virulent isolates in
dogs , which could contribute to the prevention of these
infections . -
pubmed
Experiments in
rodents showed that severe chronic stress can reduce the number of dopaminergic neurons in the substantia nigra pars compacta ( SNc ) ; the same cells that are lost in
PD . -
pubmed
All
patients developed the same symptoms of ventilatory and hemodynamic decompensation , beginning with a reduction in end - tidal
carbon dioxide , arterial desaturation , and
cyanosis on the upper trunk , and rapidly progressed to
hypotension and 2
cardiac arrests . -
pubmed
Analysis on survival and prognostic factors in
patients with resectable
pancreatic adenocarcinoma . -
pubmed
A total of 96
patients who underwent curative resection for
pancreatic cancer were included . -
pubmed
Muli bamboo (
Melocanna baccifera ) leaves ethanolic extract a non - toxic phyto - prophylactic against low pH stress and
saprolegniasis in
Labeo rohita fingerlings . -
pubmed
In the 2nd experiment ,
toxicity study was carried on
Labeo rohita fingerlings ( average length of 10.3 + - 1.5 cm and weight 18.5 + - 1.5 g ) using BLAL ( Bamboo Leaf Alcoholic ) extract and it did not show any mortalities in fish even at the dose of 20 g kg-1
body weight , which can be regarded as virtually non - toxic with minimal effect . -
pubmed
In the 4th experiment , fish were exposed to multiple stressors like low pH stress , and
Saprolegnia parastica infection after feeding with BLAL extract ( 0.1 % ) based feed for 7 days . -
pubmed
Thus , it can be concluded that the BLAL has the potentiality to be used as a non - toxic phyto - prophylactic which can induce non - specific immune response , reduces the low pH stress responses and increases the resistance against
saprolegniasis under neutral pH condition in
rohu fingerlings . -
pubmed
The aim of this study was to describe the clinical characteristics of
PHPT patients at our center from January 2005 to December 2016 . -
pubmed
METHODS : Two hundred sixty
patients with
PHPT visiting Shanghai Jiao Tong University Affiliated Sixth People 's Hospital were enrolled retrospectively . -
pubmed
RESULTS : Among all
patients , 73.1 % had symptomatic
PHPT , while the number of symptomatic and asymptomatic
patients increased 1 to 2.5 times and 1.5 to 3 times , respectively , from 2005 to 2016 . -
pubmed
CONCLUSIONS : Most
patients with
PHPT in China still exhibit classic clinical and biochemical features . -
pubmed
BACKGROUND : The non - tuberculous mycobacteria include those mycobacterium species that are not members of the
Mycobacterium tuberculosis complex , the causative agent of
pulmonary tuberculosis and
Mycobacterium leprae . -
pubmed
CASE SUMMARY : We report a case of a 62 - year - old
man who developed external popliteal sciatic nerve
paralysis after 22 days of therapy with
daptomycin . -
pubmed
Background : The
skeletal muscle toxicity that accompanies the chemotherapy drug
doxorubicin (
DOX ) may lead to
cancer patient weakness and
fatigue . -
pubmed
The grimace scale reliably assesses chronic
pain in a
rodent model of trigeminal
neuropathic pain . -
pubmed
The limited success in translating basic science findings into effective
pain management therapies reflects , in part , the difficulty in reliably assessing
pain in experimental
animals . -
pubmed
Mice and
rats were subjected to CCI - ION , and tested for changes in mechanical
hypersensitivity and in grimace scores , 10 or more days after surgery . -
pubmed
Fentanyl reversed the changes in
rat grimace scale scores , suggesting that these scores reflect
pain perception . -
pubmed
These findings validate the grimace scale as a reliable and sensitive metric for the assessment of ongoing
pain in a
rodent model of chronic , trigeminal
neuropathic pain . -
pubmed
Here , we studied the
infection status of 815
human blood donors and of 803 sympatric dogs from five , newly endemic , areas in Northwestern Italy . -
pubmed
No significant correlation between the
infection status of dogs and that of their
human owners was found , but
L. - pubmed
Conclusion : Given the current understanding of mechanical transmission of pathogens in both
humans and animals by insects belonging to the Tabanidae family which also includes Chrysops , it is plausible that the same mechanism may hold true for
hepatitis B also . -
pubmed
In this review , we have summarized the potential health benefits of
Scutellaria and its active components also the underlying mechanism of
cytotoxicity and antitumor activity . -
pubmed
D - dimer has been used as both a diagnostic and prognostic biomarker in the assessment of
patients with
venous thromboembolism , but its prognostic value in the setting of arterial
acute coronary syndromes (
ACS ) and the ability of pharmacotherapy to reduce D - dimer in
ACS is less well characterized . -
pubmed
SELECTION CRITERIA : 1 ) Randomized controlled trials , 2 ) involving older
adults ( & gt;60 years old ) , 3 ) suffering from
mental illness or cognitive decline , 4 ) comparing mind - body interventions with a control group . -
pubmed
METHODS : We enrolled 30 independently living
patients aged 18 - 75 years who had undergone THA as a treatment for primary or
secondary osteoarthritis (
OA ) between December 2015 and February 2017 . -
pubmed
The PQQ-42
strain produces more EPS ( 0.36 g l-1 ) than the
PQQ-44 strain ( 0.15 g l-1 ) , whose chemical compositions also differ . -
pubmed
METHODS : A cross - sectional study was conducted to observe
diabetic patients in the internal medicine department in Dr M. Djamil Hospital , Padang , Indonesia . -
pubmed
PURPOSE : To evaluate real - world evidence for young Japanese
patients with
rhegmatogenous retinal detachment (
RRD ) by retrospectively examining surgical procedures and clinical outcomes in the Japan Clinical Retina Study group . -
pubmed
METHODS : This was a multicentre retrospective study of the medical records of 562 young
patients ( 384
males and 178
females ; mean age : 33.0 + - 11.8 years ) who had been diagnosed with
RRD and who underwent surgical procedures in participating centres during the period between April 2013 and August 2016 . -
pubmed
CONCLUSION : Scleral buckling ( SB ) and PPV were chosen with almost equal frequency for young
patients with
RRD . -
pubmed
Diagnostic usefulness of differential time to positivity in neutropenic
cancer patients with suspected catheter - related
candidemia . -
pubmed
In affected
patients , renal function may progressively decline up to
end - stage renal disease (
ESRD ) , and approximately 10 % of those with
ESRD are affected by
ADPKD . -
pubmed
We evaluated the renoprotective effect of
octreotide - LAR in
ADPKD patients at high risk of
ESRD because of later - stage
ADPKD . -
pubmed
METHODS AND FINDINGS : We did an internally funded , parallel - group , double - blind , placebo - controlled phase III trial to assess
octreotide - LAR in
adults with
ADPKD with
glomerular filtration rate (
GFR ) 15 - 40 ml / min/1.73 m2 . -
pubmed
Over a median ( IQR ) 36 ( 24 to 37 ) months of follow - up , 9
patients on
octreotide - LAR and 21
patients on placebo progressed to a doubling of serum
creatinine or
ESRD ( composite endpoint ) ( hazard ratio [ HR ] [ 95 % CI ] adjusted for age , sex , baseline serum
creatinine , and baseline TKV : 0.307 [ 0.127 to 0.742 ] , p = 0.009 ) . -
pubmed
Among 63
patients with
chronic kidney disease (
CKD ) stage 4 , 3 on
octreotide - LAR and 8 on placebo progressed to
ESRD ( adjusted HR [ 95 % CI ] : 0.121 [ 0.017 to 0.866 ] , p = 0.036 ) . -
pubmed
Three
patients on placebo had a serious
renal cyst rupture /
infection and 1 patient had a serious
urinary tract infection / obstruction , versus 1 patient on
octreotide - LAR with a serious
renal cyst infection . -
pubmed
BACKGROUND : We conducted a comparative survival analysis between primary
androgen deprivation therapy ( PADT ) and radical prostatectomy ( RP ) based on nationwide Korean population data that included all
patients with
prostate cancer . -
pubmed
MATERIALS AND METHODS : This study enrolled 4,538
patients with
prostate cancer from the National Health Insurance Service ( NHIS ) database linked with Korean Central Cancer Registry data who were treated with PADT or RP between January 1 , 2007 , and December 31 , 2014 . -
pubmed
RESULTS :
LAB strains were mixed at equal proportions ( 1:1 ) according to mathematical planning of experiments . -
pubmed
The antifungal effect of the most active
strain Lactobacillus rhamnosus MDC 9661 in the associations with other
LAB strains was partly decreased . -
pubmed
The co - cultivation of some
strains , like
L. - pubmed
Therefore , the objectives of
hypercholesterolaemia control in
patients at high cardiovascular risk are becoming ever stricter . -
pubmed
It is to be hoped that the new guidelines that are to be issued soon by various scientific societies will define in greater detail the
patients and the conditions in which we can use PCSK9i , drugs which currently constitute the greatest advance in
hypercholesterolaemia of recent decades . -
pubmed
PURPOSE : We introduce two validated single ( SH ) and dual hormone ( DH ) mathematical models that represent an in - silico virtual
patient population ( VPP ) for
type 1 diabetes (
T1D ) . -
pubmed
We present validation results comparing these virtual patients with true clinical
patients undergoing AP control and demonstrate that the virtual patients behave similarly to
people with
T1D. -
pubmed
We evaluated the SH - VPP and DH - VPP on a clinical data set of 20
people with
T1D who participated in a 3.5 - day outpatient AP study . -
pubmed
We compared percent time in target range ( 70 - 180 mg / dL ) , time in
hypoglycemia ( & lt;70 mg / dL ) and time in
hyperglycemia ( & gt;180 mg / dL ) for both the virtual
patients and the actual
patients . -
pubmed
RESULTS : The subjects in the SH - VPP performed similarly vs. the actual
patients ( time in range : 78.1 + - 5.1 % vs. 74.3 + - 8.1 % , p = 0.11 ; time in
hypoglycemia : 3.4 + - 1.3 % vs. 2.8 + - 1.7 % , p = 0.23 ) . -
pubmed
The subjects in the DH - VPP also performed similarly vs. the actual
patients ( time in range : 75.6 + - 5.5 % vs. 71.9 + - 10.9 % , p = 0.13 ; time in
hypoglycemia : 0.9 + - 0.8 % vs. 1.3 + - 1 % , p = 0.19 ) . -
pubmed
Recent clinical trials using
cancer and
non - cancer patients with
chronic fatigue have shown the benefit of Molecular Replacement Therapy plus antioxidants in restoring mitochondrial electron transport function , reducing moderate to severe
chronic fatigue and protecting mitochondrial and other cellular structures and enzymes from oxidative or other damage due to cytotoxic therapy . -
pubmed
In
animal models of
IUGR , long - term persistent changes in both DNA methylation and expression of genes implicated in metabolic processes have been repeatedly reported . -
pubmed
Findings from
human studies confirming the role of epigenetic mechanisms in linking early - life adverse experiences to the risk for
T2D in adult life are scarce compared to data from
animal studies , mainly because of limited access to suitable biological samples . -
pubmed
Cysticercosis cellulosa cutis is caused by larval stage of
Taenia solium . -
pubmed
In this study , we find that miR-204 - 5p expression is reduced in
PCa tissues and serum sample with
bone metastasis compared with that in
PCa tissues and serum sample without bone
metastasis , which is associated with advanced clinicopathological characteristics and poor bone metastasis - free survival in
PCa patients . -
pubmed
Diffuse variants of scalp
Lichen Planopilaris : clinical , trichoscopic and histopathologic features of 40
patients . -
pubmed
OBJECTIVES : The medical features of 40
patients affected by a diffuse hair thinning associated with a long - lasting history of
pruritus and
erythema of the scalp and a histopathological diagnosis of
LPP were reviewed . -
pubmed
RESULTS : Eighteen
patients were diagnosed with
FAPD and two
patients with
CPHL . -
pubmed
CONCLUSIONS : In
patients complaining of a long - lasting history of scalp
erythema ,
itching /
dysesthesia and diffuse hair thinning it 's advisable to consider diffuse variants of
LPP . -
pubmed
Brain functional connectivity data enhance prediction of clinical outcome in
youth at risk for
psychosis . -
pubmed
This study assesses a combined clinical and resting - state fMRI prediction model in 137
adolescents and young adults at Clinical High Risk ( CHR ) for
psychosis from the Shanghai At Risk for
Psychosis ( SHARP ) program . -
pubmed
OBJECTIVE : Impairments generally persist when
children diagnosed with
attention - deficit / hyperactivity disorder (
ADHD ) mature into adolescence . -
pubmed
North American hibernating bat species are threatened by the psychrophilic fungus
Pseudogymnoascus destructans ( Pd ) causing the disease called
white - nose syndrome (
WNS ) with unprecedented mortality rates . -
pubmed
We identified differentially expressed proteins for
acute phase response , constitutive and adaptive immunity , oxidative stress defense , metabolism and structural proteins of exosomes and desmosomes , suggesting a systemic response against
Pd in North American
M. - pubmed
Results : In this study , 625 laboratory - confirmed
COVID-19 patients were enrolled ; among them , 179
patients without an initial CT at admission and 25
patients aged < 18 years old were excluded and 421
patients were included in analysis . -
pubmed
To assess if there is a correlation between femoral neck - shaft angle ( NSA ) and the distance of the ischiofemoral space ( IFS ) and quadratus femoris space ( QFS ) and to determine the prevalence of quadratus femoris ( QF )
edema in
patients with
hip pain . -
pubmed
A retrospective case series was conducted involving 100 consecutive hip or pelvis magnetic resonance imaging scans on
patients presenting with
hip pain . -
pubmed
A similar decrease in ADCC titers was observed in Hvem-/-
mice vaccinated with an alternative HSV vaccine candidate ( dl5 - 29 ) or an unrelated
vesicular stomatitis virus - vectored vaccine . -
pubmed
METHODS : We included 101
MS patients and 77 healthy
subjects in this study . -
pubmed
BACKGROUND : Although pelvic osteotomy ( PO ) is an important surgical procedure that can alleviate symptoms and potentially slow progression of
osteoarthritis in
patients with
development dysplasia of the hip , some
patients eventually require conversion to total hip arthroplasty ( THA ) . -
pubmed
METHODS : Forty nine
patients with a history of prior PO who underwent conversion THA at a single institution were matched at a 1:3 ratio based on the date of surgery , age , gender , and
body mass index with 147
developmental dysplasia of the hip patients who underwent primary THA without prior PO . -
pubmed
RESULTS :
Patients with prior PO required more supplemental screw fixation for the acetabular component ( 59.2 % vs 38.1 % , P = .016 ) , more autologous bone grafting ( 24.5 % vs 11.6 % , P = .048 ) , had a longer mean operative time ( 106.0 vs 79.8 minutes , P < .001 ) , and greater estimated
blood loss ( 350.0 vs 206.8 mL , P = .015 ) . -
pubmed
We discuss the most common temporary mechanical circulatory support ( tMCS ) devices used for
patients in
cardiogenic shock , including the intra - aortic balloon pump ( IABP ) , transvalvular axial flow support systems ( Impella ) , the Tandem collection , and extracorporeal membrane oxygenation ( ECMO ) . -
pubmed
Objective : To describe the frequency and predisposing factors of
aortic structural disease among
patients with biopsy - proven
giant cell arteritis (
GCA ) . -
pubmed
Method : A retrospective review identified all
patients with biopsy - proven
GCA from 1998 to 2013 with aortic imaging . -
pubmed
Conclusion :
Thoracic aortic aneurysm / dilatation was seen in 8 % of
patients at baseline . -
pubmed
Among
patients without
aortic disease , the cumulative incidence of
aortic disease was 10 % at 5 years after diagnosis . -
pubmed
This note reports the first finding of clown beetles ( Coleoptera , Histeridae ) in a
hive aggregation of stingless and
honey bees in natural conditions and expands the known distribution of the species to the state of Espirito Santo , the second record in the Brazilian Atlantic Forest . -
pubmed
,
diabetes and
obesity ) has seriously affected
human health and life safety worldwide . -
pubmed
Both
animal and clinical studies have proved that
BBR has good therapeutic effects on these five
metabolic diseases . -
pubmed
All - cause
death occurred in 2.5 % of
patients assigned to experimental and 2.9 % of
patients assigned control therapy ( hazard ratio [ HR ] , 0.91 , 95 % CI , 0.75 - 1.11 ; P=0.37 ) . -
pubmed
Overall ,
patients treated with experimental versus control therapy showed no significant difference in terms of
myocardial infarction ( HR , 1.02 [ 0.85 - 1.22 ] , P=0.81 ) ,
stent thrombosis ( HR , 1.02 [ 0.87 - 1.20 ] , P=0.83 ) , or
stroke ( HR , 1.01 [ 0.68 - 1.49 ] , P=0.96 ) . -
pubmed
Conclusions In
patients treated with percutaneous coronary intervention and stenting , assigned to a strategy of early
aspirin discontinuation versus
DAPT , the risk of
death and
ischemic events is not significantly different but the risk of
bleeding is lower . -
pubmed
Subsequently ,
hydroxycarbamide proved efficacious in
adults with
SCA and was Food and Drug Administration ( FDA)-approved in 1998 . -
pubmed
Parallel efforts to develop curative therapies using haematopoietic stem cell transplant and gene therapy provide
individuals with
SCD multiple treatment options . -
pubmed
The target of the current research is to assess the antiarthritic efficacy of BM - MSCs ( 106 cells /
rat at 1 , 6 , 12 and 18 days ) and
IMC ( 2 mg / kg
body weight / day for 3 weeks ) either alone or concurrently administered against complete Freund 's adjuvant - induced
arthritic rats . -
pubmed
Patients exhibited changes in the thalamus , posterior thalamic radiations and sagittal stratum on brain MRI and demonstrated
impaired cognitive performance , specifically in the executive and visuospatial domains . -
pubmed
Nursing of a
patient with
stroke and improvement of the dememted state with agressive care ] . -
pubmed
Clinical review of
cervical spine injuries in
children . -
pubmed
Clinical presentation is made of 18
cervical fractures occurring in
children age 15 and under . -
pubmed
The data suggest that the elicited imitation procedures can be effectively used to increase the precision of the evaluation and clinical programming of
children with
language disorders . -
pubmed
Paraplegia developed in a 70 - year - old
man after resection of a ruptured
abdominal aortic aneurysm during which aortic occlusion time was 45 minutes . -
pubmed
Only four
patients have previously been reported to recover from
paraplegia produced in this manner . -
pubmed
Paraplegia is more common in
patients with
hypotension and when backbleeding from the lumbar arteries has been poor . -
pubmed
Fourteen cases of
patients with
photoconvulsive response during intermitent luminous stimulation ( eleven
women and three
men ) are reviewed . -
pubmed
Sustained and transient
ganglion cells in the
cat 's retina : spatial distribution of centre and surround receptive field mechanisms . -
pubmed
[
Heterotopic ossifications in a
patient with severe
craniocerebral trauma ] . -
pubmed
Patients with severe
head injury and
fractures of joints or of long bones often show a
hypertrophic callus formation which leads to a rapid consolidation of a
fracture but can also lead to an
ankylosis of the joints . -
pubmed
Seasonal occurrence of
Karoo paralysis in Angora
goats in relation to the infestation density of female
Ixodes rubicundus . -
pubmed
The seasonal occurrence of
Karoo paralysis in relation to the infestation density of female
Ixodes rubicundus was investigated in an enzootic area of the southwestern Orange Free State , South Africa . -
pubmed
Only the young
goats became paralysed and their infestation densities ( female ticks kg-1 host
body weight ) were significantly higher than those of healthy animals . -
pubmed
Monoclonal antibody B72.3 immunoscintigraphy in the follow - up of
patients with
colorectal cancer . -
pubmed
We describe EEG findings and clinical outcomes of 24
Alzheimer (
AD )
patients over a 3 year follow - up period . -
pubmed
At year 3 , only 2
patients still had normal EEGs and mild
dementia , probably representing a subgroup of
AD with a benign course , 7
patients needed institutional care and 3 had died . -
pubmed
The results support the idea of heterogeneity of
AD patients and suggest that EEG may provide valuable information for prediction of outcome . -
pubmed
[ Clinical usefulness of quantitative two - dimensional echocardiographic analysis of segmental kinesis of the left ventricle in monitoring of
patients with
neoplasms treated with
anthracyclines ] . -
pubmed
To determine whether serial quantitative two - dimensional echocardiographic analysis of left ventricular wall motion could be effective in selecting
patients in whom
anthracycline treatment must be stopped , 26
patients ( 18 M and 8 F , mean age 10 + /- 3 , range 6 to 16 years ) with
malignancy , receiving
doxorubicin or
daunomycin were followed up . -
pubmed
The following distribution of left ventricular contraction abnormalities was noted : septal , anteroseptal and posteroseptal
akinesis with
posterior wall hypokinesis in one
patient ; septal , anteroseptal and posteroseptal
akinesis with anterolateral free - wall
hypokinesis in another ; septal , anteroseptal and posteroseptal
hypokinesis in four ; lateral and posterolateral free - wall
hypokinesis in one ; septal , anteroseptal , posteroseptal and posterior
hypokinesis in four . -
pubmed
The drug was discontinued in only two
patients with
akinesis , since we regarded this contraction abnormality as a predictive index of more serious and extensive
myocardial damage . -
pubmed
A femoroperoneal bypass using a cryopreserved
human saphenous allograft was performed on a
patient who presented with critical
ischemia of the left lower extremity . -
pubmed
The
patient died of
myocardial infarction 48 hours later and the graft was examined histologically . -
pubmed
The histologic changes that occur in cryopreserved venous allografts are similar in experimental and
human material and may be the result of
anoxia of the vessel wall rather than immunologic mechanisms . -
pubmed
In 85
patients background factors such as
diabetes , age , sex and side of operation were analysed and found not to influence the degree of
edema . -
pubmed
Within the leg elevation group there was , like in
patients without special treatment , less
swelling if the distal anastomosis was performed above the knee and if a prosthetic graft was used . -
pubmed
In these cases leg elevation seemed to prevent
swelling with significantly less
edema than corresponding
patients treated without leg elevation . -
pubmed
METHOD : Fifty - nine
outpatients with
major depression with endogenous features , according to Research Diagnostic Criteria , were stratified into more severe ( score of 20 or more on the Hamilton Rating Scale for
Depression ; N = 38 ) or less severe ( Hamilton score of 19 or less ; N = 21 ) subgroups . -
pubmed
CONCLUSIONS : These results partially replicate the National Institute of Mental Health 's Treatment of
Depression Collaborative Research Program 's findings of poorer response to cognitive behavior therapy in
patients with Hamilton scale scores of 20 or more . -
pubmed
Identification of
patients at increased risk for potentially malignant
arrhythmias . -
pubmed
Appropriate identification of patients at high risk for malignant
ventricular arrhythmias requires subclassification by disease entity , historic information about
syncopal episodes , noninvasive testing , and invasive electrophysiologic studies in selected
patients . -
pubmed
We report on a
patient with
small - cell carcinoma of the esophagus treated with combination chemotherapy consisting of
cyclophosphamide ,
vincristine , and
VP-16 followed by local radiation therapy . -
pubmed
A report is given on the natural history of
multi - infarct dementia (
MID ) in 94
patients over a period of 5 years and describes neuroimaging criteria that may be used in order to more reliably separate vascular (
VD ) from primary degenerative types of
dementia (
DTD ) . -
pubmed
The annual mortality rate of
MID patients was 13 % . -
pubmed
The typical patchy pattern found in almost half of the
patients with
VD , and significant differences in 5 - 7 Hz range as shown by EEG mapping can also be used for increasing the accuracy of the clinical diagnosis . -
pubmed
DCB exhibited both direct and
H2O2 - dependent
mutagenicity to both tester strains
TA98 and TA98/
1,8 - DNP6 . -
pubmed
DCB , in contrast to its effects in tester
strains TA98 , was not mutagenic to
TA100 and
TA102 either directly or in the presence of
H2O2 . -
pubmed
Graft versus
leukemia effect in
man : the
relapse rate of
acute leukemia is lower after allogeneic than after syngeneic marrow transplantation . -
pubmed
To determine whether allogeneic bone marrow transplantation ( BMT ) is associated with a graft vs
leukemia (
GVL ) effect in
man , the
relapse rate of
acute leukemia after allogeneic BMT was compared with that occurring after syngeneic ( genetically identical twin ) BMT . -
pubmed
Experimentally induced
photosensitization in
cattle with
Cooperia pedunculata . -
pubmed
Photosensitization was induced in 2
Charolais heifers following administration of a mixture of air - dried , ground , green ( 75 % ) and dead ( 25 % ) leaves of the south
Texas forb ,
Cooperia pedunculata , and subsequent exposure to sunlight . -
pubmed
Plant material used in this study was collected from a pasture where natural cases of primary
bovine photosensitization were occurring . -
pubmed
A second
heifer developed signs of mild
photosensitization following administration of plant material at 1.7 g / kg / d for 4 days . -
pubmed
Clinical and pathologic findings of this trial were consistent with the primary form of
photosensitization observed in natural cases seen in
cattle of south Texas exposed to this plant . -
pubmed
Quantitative transplantation techniques have been employed to study radiogenic
cancer initiation frequency and cell interactions during promotion / progression in grafted clonogenic
rat thyroid epithelial cells . -
pubmed
aureus - infected milk samples ( 7 % ) from
cows with chronic
staphylococcal mastitis . -
pubmed
Failure to detect leukocidin in most mastitic milk samples with this assay indicated that , if leukocidin is produced in the
bovine mammary gland during chronic
staphylococcal mastitis , the concentration of the toxin may be too low to produce cytolytic effects on neutrophils . -
pubmed
The mixture of capped in vitro transcripts from all three clones produced normal
CCMV infections in
barley protoplasts and
cowpea plants . -
pubmed
Histological and electrophysiological studies were performed in Lewis
rats with
experimental allergic encephalomyelitis (
EAE ) to determine the cause of the neurological signs . -
pubmed
It is concluded that
demyelination - induced
conduction block in this region is an important cause of
hindlimb weakness and
paralysis in Lewis
rats with
EAE . -
pubmed
Toxicity of
pyrethroids to
Aedes aegypti larvae in relation to temperature . -
pubmed
The influence of temperature on the
toxicity of the
pyrethroids cypermethrin ,
permethrin ,
fenvalerate ,
d - phenothrin ,
flucythrinate and
bioallethrin to 3rd instar
Aedes aegypti larvae was determined . -
pubmed
Blood samples from 23
subjects with
chronic renal failure and 19 controls were tested using thrombelastography and other hematologic tests . -
pubmed
In vitro and ex vivo effect of
cimetidine on
human platelet aggregation . -
pubmed
The TBS is effective and may have wide application in producing amplification in good sound fidelity when used in
patients who have external canal , middle ear , or
eustachian tube disease that is poorly corrected by surgery or conventional hearing aids . -
pubmed
In order to determine whether superior cervical
ganglion ( SCG ) fibers sprouting into the hippocampus contribute to behavioral recovery , 31
Sprague - Dawley rats were first trained on a forced - choice task . -
pubmed
Early responses of liver to
cortisone in
alloxan -
diabetic rats . -
pubmed
The efficacy of fine - detail radiography in the evaluation of
patients with
rheumatoid arthritis . -
pubmed
Effect of
halothane anesthesia on experimental Salmonella
peritonitis in
mice . -
pubmed
Cochlear otosclerosis : a
human temporal bone report . -
pubmed
[ On the immunization of white
mice against
ectromelia by means of an active vaccine virus . -
pubmed
Effect of immunosuppressive drug therapy on blood
urea nitrogen concentration in
dogs with
azotemia . -
pubmed
Azotemic dogs receiving
prednisone and
azathioprine to enhance renal allograft survival had higher blood
urea nitrogen ( BUN):serum
creatinine ( SC ) ratios , when compared with nontreated
dogs with induced
azotemia . -
pubmed
However ,
dogs with naturally occurring
renal failure had
BUN : SC ratios that were similar to those for
dogs receiving the catabolic drugs . -
pubmed
It was concluded that even though catabolic drugs may influence
BUN : SC ratios , the multiplicity of other factors affecting
BUN and SC may interact to cause a wide range of
BUN : SC ratios under conditions of naturally occurring
primary renal failure in the
dog . -
pubmed
Fatty liver syndrome or
hepatic lipidosis (
HL ) is a condition thought to contribute to an increased incidence of
peripartum disease , reduced response to therapy and decreased fertility in dairy
cows . -
pubmed
The effect of
alcohol on the
toxicity of
acetaminophen in
mice . -
pubmed
The present report describes our results in using
alcohol as an antidote for
acetaminophen overdose in the
mouse model . -
pubmed
Alcohol thus appears to be an effective antidote for
acetaminophen overdose in the
mouse model , when given at an appropriate time and dose . -
pubmed
Four
patients with
aneurysmal bone cysts of the rib are presented and previously reported cases reviewed . -
pubmed
Most
steroid - dependent
asthmatic patients can be successfully controlled with the drug , at least most of the time , and the therapeutic effect is dose dependent . -
pubmed
It is important that
patients treated with
steroid aerosols continue to receive other effective therapeutic agents , notably adrenergic drugs , particularly by aerosol , and
theophylline compounds ; that they learn how to inhale the aerosol properly ; and , most important , that they promptly start taking oral
steroids when they experience an exacerbation of
asthma . -
pubmed
A breeding study to control chronic progressive
nephrosis in
rats . -
pubmed
The selection of low excretor males for breeding stock appears to offer a practical basis for minimizing the total expression of chronic progressive
nephrosis in this
strain of
rat . -
pubmed
The Schaefer seroagglutination test is useful in epidemiologic studies of
nontuberculous mycobacteria , especially the
Mycobacterium avium - intracellulare - scrofulaceum complex . -
pubmed
We assessed the long - term results of our experience with 109
patients with end - stage
cardiopulmonary disease who underwent primary combined heart - lung transplantation at Stanford University Medical Center between March 1981 and January 1994 . -
pubmed
Causes of
death included
hemorrhage ( five
patients ) ,
infection ( 21 ) , rejection ( one ) , nonspecific
pulmonary failure ( four ) , graft
coronary artery disease ( six ) , and
obliterative bronchiolitis ( eight ) . -
pubmed
Only 20 % + /- 3.9 % of
patients were free from any
infection 3 months after transplantation . -
pubmed
Although graft
coronary artery disease developed less frequently than in
patients after isolated heart transplantation ( 90 % + /- 4.6 % of
patients were free of graft
coronary artery disease at 5 years ) , obliterative
bronchiolitis remains a major long - term complication and cause of morbidity and mortality . -
pubmed
Involvement of free radicals in
cisplatin - induced
emesis in
Suncus murinus . -
pubmed
The participation of free radicals in
cisplatin - induced
emesis was investigated in the
house musk shrew ,
Suncus murinus . -
pubmed
A
patient is described who developed an intramural
haematoma of the oesophagus shortly after variceal endoscopic sclerotherapy . -
pubmed
Clinically , sensory or sympathetic damage caused
incontinence , but sympathectomy also caused high pressure waves , which may cause
upper tract damage and treatment resistant
incontinence in
patients . -
pubmed
cereus H.1 reacted not only with the homologous specific antigen but also reacted with the flagellar antigens of 23
strains of
B. - pubmed
cereus also reacted with flagellar antigens of 21
strains of
Bacillus thuringiensis by ELISA . -
pubmed
Effects of washing acid
injuries to the skin with water : an experimental study using
rats . -
pubmed
A
skin acid injury model has been constructed using SD
rats and
1N HCl . -
pubmed
After inflicting an acid
injury , the subcutaneous tissue pH of control
animals reached its minimum value at the seventh minute , and had not recovered to the pre - experimental level by the 60th minute . -
pubmed
[
Eye lesions in
patients with
pulmonary sarcoidosis ] . -
pubmed
Sarcoidosis involvement of the eyes was revealed in 36 % of
patients with
sarcoidosis of the respiratory organs . -
pubmed
Natural history of abnormal conduction and its relation to prognosis in
patients with
dilated cardiomyopathy . -
pubmed
To investigate the natural history of disturbances in ventricular activation , atrioventricular conduction , and ventricular cavity size , we retrospectively studied 58
patients from a total of 296
patients with
dilated cardiomyopathy seen within 4 years . -
pubmed
PATIENTS : Forty - six
patients with definite chronic progressive
MS ; 20 received treatment and 26 were in a nontreatment comparison group ( " waiting list " ) . -
pubmed
RESULTS : The
patients were divided into four outcome groups ( failure , fair , good , and excellent ) based on a scoring table that adds or subtracts points while evaluating three main areas : percentage of excess
weight loss , changes in medical conditions , and assessment of quality of life . -
pubmed
Magnetic resonance imaging analysis of left ventricular function in normal and spontaneously
hypertensive rats . -
pubmed
We have used magnetic resonance imaging ( MRI ) to examine acute morphological changes in the left ventricle throughout the cardiac cycle in normal
Wistar Kyoto rats ( WKY ) and also to follow the development of chronic changes in spontaneously
hypertensive rats ( SHR ) . -
pubmed
The Batista operation was performed in 30
patients ( 25
men and 5
women , mean age 47 years ) to treat
cardiac failure due to
non - ischemic cardiomyopathy , mostly
idiopathic dilated cardiomyopathy , from December 1996 to June 1998 . -
pubmed
Seven
patients required emergency surgery because of on - going
shock and 23
patients were operated electively . -
pubmed
Effects of
Ehrlich ascites carcinoma cells on the responses of non - pregnant and pregnant uterine smooth muscles of
mice to
oxytocin and
acetylcholine . -
pubmed
On the other hand , induction of pregnancy in control non -
tumor bearing
mice significantly increases the sensitivity of the uterine smooth muscles to
oxytocin as well as to
ACh . -
pubmed
In
tumor bearing
mice , the induction of pregnancy significantly reduced the sensitivity of the uterine smooth muscles to
oxytocin and
ACh when compared with the uterine muscles obtained from pregnant non -
tumor bearing
mice . -
pubmed
It is also providing an
animal model in which to test therapies aimed at reducing hemodynamic stress and the collapse of the aortic matrix during dissecting
aneurysm . -
pubmed
The
patients were nine
women with mild
preeclampsia and , for comparison , nine control
women matched for gestation and parity . -
pubmed
RESULTS :
Women with mild
preeclampsia had higher
norepinephrine levels throughout 25 h , and lower systemic
prostacyclin production as measured by the urinary
2,3 - dinor-6 - keto PGF1 alpha excretion during the daytime . -
pubmed
The majority of
HD patients require intravenous
iron therapy to achieve the hematocrit levels that correspond to improved outcome measures . -
pubmed
Specifically , no data unequivocally confirm that
iron overload from parenteral
iron contributes to all - cause
patient morbidity or mortality . -
pubmed
The
rat middle cerebral artery ( MCA ) was occluded by a
thrombus induced by photochemical reaction between green light and the photosensitizer dye , Rose Bengal . -
pubmed
ONO-5046 at doses of 10 and 30 mg / kg / h significantly ( p<0.05 and p<0.01 , respectively ) reduced the size of
cerebral damage and water content ( p<0.05 , p<0.01 , respectively ) in different eight
rats . -
pubmed
To date , 7
patients have been reported with clinical symptoms suggesting a
neurodegenerative disease . -
pubmed
At birth , the male
patient suffered from mild
perinatal asphyxia due to
meconium aspiration . -
pubmed
Evaluating a new strategy for prophylaxis to prevent
Pneumocystis carinii pneumonia in
HIV - exposed infants in Thailand . -
pubmed
METHODS :
HIV - infected women were offered
trimethoprim - sulfamethoxazole for
PCP prophylaxis for their
children at 1 - 2 months of age . -
pubmed
A 15 - year follow - up of a
boy with
pyridoxine (
vitamin B6)-dependent
seizures with
autism , breath holding , and severe
mental retardation . -
pubmed
Most
patients with
pyridoxine - dependent
seizures require lifelong treatment with
pyridoxine . -
pubmed
We report a 15 - year - old
boy with
pyridoxine - dependent
seizures ,
nonpyridoxine - dependent
seizures , severe
mental retardation ,
autistic disorder ,
aerophagia , breath holding , and self -
injury . -
pubmed
Is compensatory vasoconstrictor tone in the hindquarter vascular region induced by
hemorrhage in conscious spontaneously
hypertensive rats ? -
pubmed
We investigated whether a compensatory vasoconstrictor action would be induced by a
hypotensive intervention in the hindquarter vascular region of conscious spontaneously
hypertensive rats ( SHRs ) . -
pubmed
Healing index averaged 30 days / cm ( 27 days / cm when two
patients with
radial nerve palsy were excluded ) . -
pubmed
Transient
radial nerve palsy developed during lengthening in two
patients , and lengthening was discontinued . -
pubmed
Symptoms of
radial nerve palsy resolved completely in both
patients , but one
patient required an additional surgery to explore the radial nerve for persistent
paresthesia of the forearm . -
pubmed
Bilateral humeral lengthening was very effective for improving function and overall proportion in
patients with
achondroplasia . -
pubmed
Biological characteristics and chemosensitivity profile of four
human anaplastic thyroid carcinoma cell lines . -
pubmed
The xenotransplantation of the lines in athymic
nude mice produced
tumors with a histology similar to the original
tumors . -
pubmed
We have studied 34
individuals in a large 84 - member four - generation central Illinois family with autosomal dominant
Charcot - Marie - Tooth and
deafness . -
pubmed
Audiological evaluation revealed both
auditory neuropathy and cochlear involvement in affected
individuals . -
pubmed
Another
individual died at the age of 3 months from
hypotonia later attributed to
CMT . -
pubmed
These results raise an important additional concern for the health consequences of
nicotine abuse and open new insight on the possible neural mechanisms of
tobacco addiction . -
pubmed
Safety of
abacavir therapy after temporary interruptions in
patients without
hypersensitivity reactions to the drug . -
pubmed
The efficacy of Liposem , a polyherbal formulation , as an antioxidant and hypolipidaemic drug was evaluated in diet induced
hyperlipidaemia in
rats . -
pubmed
The hypolipidaemic effect was assessed by serum lipid profile in dietary
hyperlipidaemic rats and found to have decreased dose dependently in all the four different concentrations of administration ( 100 , 200 , 300 and 400 mg / kg body wt ) . -
pubmed
This is a retrospective study of 276
patients consisting of 157 active and 119 reactive
patients of
borderline leprosy . -
pubmed
Similar effects in
humans may contribute to the increased incidence of
psychiatric illness in
individuals exposed to early life adversity . -
pubmed
Comparison of quality of life and arm complaints after axillary lymph node dissection vs sentinel lymph node biopsy in
breast cancer patients . -
pubmed
The sentinel lymph node biopsy ( SLNB ) represents a minimal invasive surgical method for axillary staging in
patients with primary
breast cancer . -
pubmed
Arm /
shoulder pain was reported in 36 % of patients after SLNB in comparison to 68 % receiving axillary lymph node dissection ( ALND ) , and '
numbness ' was reported only in 4 % of
patients in the SLNB group vs 19.3 % after ALND . -
pubmed
Effect of pregnancy and lactation on
granuloma tissue formation and joint permeability in
rats . -
pubmed
MRI plays a strategic role in
patient care for initial evaluation and treatment planning in
patients with
ovarian cancer . -
pubmed
[ Clinical factors associated with response to biofeedback therapy for
patients with
chronic constipation ] . -
pubmed
METHODS : Biofeedback treatment was performed in 114
patients with
constipation . -
pubmed
Using prognostic factors , we may be able to evaluate the patterns of
pelvic floor dysfunction and responsiveness of biofeedback therapy for the
patients with
constipation . -
pubmed
Changes in intraocular pressure ( IOP ) elicited by a Valsalva manoeuvre were studied in 11 male
patients ( mean age 39.8 years ) suffering from episodic
cluster headache (
CH ) , and 12 healthy male controls ( mean age 39.9 years ) . -
pubmed
It has been reported that the oral administration of
TAS-102 increases the AUC of
FTD in
rodents and
monkeys in different manners . -
pubmed
Based on this modeling , we were able to quantitatively explain the
TPI dose - dependent enhancement of AUC of
FTD in
monkeys , while little increase was observed in
rats . -
pubmed
The differences in in vivo erythropoietic activity among glycosylation analogs were more evident with increased time following administration in exhypoxic
polycythemic mice . -
pubmed
Neosporosis in a young
dog presenting with
dermatitis and
neuromuscular signs . -
pubmed
A 16 - week - old , male boxer
dog developed
multifocal nodular dermatitis followed by rapidly progressive and fatal
neuromuscular disease . -
pubmed
Serology suggested active
infection with
Neospora caninum . -
pubmed
However ,
hearing loss and exposure to various environmental sounds can lead to changes in multiple organ systems , making what laboratory
animals hear of consequence for researchers beyond those solely interested in hearing . -
pubmed
For example , several inbred
mouse strains commonly used in biomedical research ( e.g. -
pubmed
Both researchers and laboratory
animal facility personnel should be aware of both
strain and species differences in hearing in order to minimize potentially confounding variables in their research and to aid in the interpretation of data . -
pubmed
OBJECTIVES : To investigate whether or not impairment of
HPV contributes to the
hypoxemia associated with
HVT and to evaluate the role of LTs in ventilator - induced
lung injury . -
pubmed
RESULTS : In wild - type
mice , HVT , but not LVT , increased pulmonary vascular permeability and
edema formation , impaired systemic oxygenation , and reduced survival . -
pubmed
We present one
patient with multiple
upper tract carcinoma treated with percutaneous surgery and BCG . -
pubmed
Twenty - five
human cadavers were examined to study the anatomy of the closed vascular system between the retroauricular artery and the retroauricular vein in the skin on the posterior aspect of the auricle and the mastoid process . -
pubmed
Our data show that RNAi results in stably inherited phenotypes and therefore represents an efficient tool for functional genomic studies in
polyploid wheat . -
pubmed
Comparison between serum and urinary
sulphadimidine acetylation as predictors of
isoniazid acetylator status in
patients with
pulmonary tuberculosis . -
pubmed
The acetylator status of 200
pulmonary tuberculosis patients was determined by
sulphadimidine (
SDM ) acetylation in ( 1 ) urine and ( 2 ) serum . -
pubmed
SUBJECTS AND METHODS : Between 1998 and 2004 , 135
patients consecutively presenting with a
parotid mass were prospectively enrolled into this study . -
pubmed
Children who receive a diagnosis of
bipolar disorder in community settings typically present with rapid fluctuations in mood and behavior , often associated with comorbid
attention - deficit / hyperactivity disorder and
disruptive behavior disorders . -
pubmed
METHODS : We examined 45 male
patients ( median age , 8 months ; range 3 - 28 ) with total
epispadias and classic
bladder exstrophy , combined with
cryptorchidism . -
pubmed
BACKGROUND : Documentation of
superfoetation is extremely rare in
humans . -
pubmed
OBJECTIVE : The aim of the present study was to compare health - related quality of life ( HRQoL ) measures in euthymic
patients with
bipolar I and II disorder . -
pubmed
METHOD : HRQoL was assessed using the Medical Outcomes Study 36 - Item Short - Form Health Survey ( SF-36 ) in 253 subjects recruited in 5 Italian centers : 90
patients with
bipolar I disorder , 52
patients with
bipolar II disorder , 61 subjects with
RMD , and 50 healthy comparison individuals . -
pubmed
CASE : A 26 - year - old , primiparous
woman , 32 weeks pregnant , presented with a 1 - day history of
pain in the upper abdomen . -
pubmed
Initially the
patient was managed conservatively on the suspicion of
gastritis , but she did not respond . -
pubmed
We demonstrate that this method can detect a single molecule of PicoGreen - stained mtDNA in intact DsRed2 - labeled mitochondrial particles isolated from
human osteosarcoma 143B cells . -
pubmed
Docetaxel monotherapy as second - line treatment for pretreated advanced
non - small cell lung cancer patients . -
pubmed
BACKGROUND : Second - line chemotherapy offers advanced
non - small cell lung cancer (
NSCLC )
patients a small , but significant increase in survival . -
pubmed
Hyperleukocytosis without other complications may not be an indication for adding cytotoxic therapy or
steroids , nor for discontinuing
arsenic trioxide therapy in
children . -
pubmed
Burn patients over the age of 60 are at a greater risk for developing
pulmonary complications than younger
patients . -
pubmed
At 6 or 24 h after receiving sham or 15 % total body surface area
scald injury , lungs from young and aged
mice were analyzed for leukocyte content by histological examination and immunostaining . -
pubmed
At 24 h , in contrast , neutrophils returned to sham levels in the lungs of young ,
burn - injured
mice ( P<0.05 ) but did not change in the lungs of aged ,
burn - injured
mice . -
pubmed
Changes in circulation of B and
non - B HIV strains : spotlight on a reference centre for
infectious diseases in Northern Italy . -
pubmed
In the period 1980 - -1982 , new
infections were entirely caused by
HIV-1 subtype B strains and were all diagnosed in injection drug users , 88.9 % of whom were males . -
pubmed
In conclusion , a picture of the changing scenario of circulating
HIV types and subtypes in a reference
Infectious Diseases centre in Northern Italy over the past 26 years is provided . -
pubmed
A progressive modification in risk factors for
HIV infection and a significant increase in the frequency of
non - B HIV strains were observed . -
pubmed
A 43 - year - old
man presented with a 2 - month history of left upper lobectomy due to an atypical
lung carcinoid tumor . -
pubmed
Malaria is currently highly prevalent and restricted to the north of Brazil , and its dynamics are severely affected by
human environmental changes , such as the large dam construction recently approved by the Brazilian Government in Rondonia . -
pubmed
As
HH is a major risk factor for
brain injury and subsequent neurodevelopment handicap , the identification , rapid diagnosis and prompt management of
patients with
HH is essential if
brain damage is to be avoided . -
pubmed
Advances in molecular genetics , radiological imaging techniques ( such as
fluorine-18 L-3 , 4 - dihydroxyphenylalanine positron emission tomography (
( 18F ) DOPA - PET ) scanning ) and laparoscopic surgery have completely changed the clinical approach to
infants with the severe congenital forms of
HH . -
pubmed
The introduction of Rituximab has greatly improved therapeutic options for
patients with
B - cell non - Hodgkin lymphoma (
B - NHL ) . -
pubmed
However , a substantial fraction of
patients with aggressive
B - NHL fails first - line therapy , and most
patients with relapsing indolent B -
NHL eventually acquire Rituximab resistance . -
pubmed
METHODS : A total of 108
patients who had
HCC were classified according to these systems . -
pubmed
Endoscopic biliary drainage for
choledocholithiasis in a
patient with
aplastic anemia before hematological engraftment after allogeneic transplantation . -
pubmed
A 30 - year - old
man was diagnosed with severe
aplastic anemia in 1997 . -
pubmed
One option is based on the vaccination of
cancer patients with autologous inactivated intact
tumor cells . -
pubmed
BACKGROUND : Affecting the core functional microbiome , peculiar high level taxonomic unbalances of the
human intestinal microbiota have been recently associated with specific diseases , such as
obesity ,
inflammatory bowel diseases , and intestinal
inflammation . -
pubmed
Trichinella infection was detected in 1 puma [ 2 larvae per gram ( LPG ) ] , 3 wild boars ( 8 - 420 LPG ) , 3 armadillos ( 0.04 - 0.08 LPG ) , and 9
rats ( 0.1 to 150 LPG ) . -
pubmed
The presence of
Trichinella infection among wild animal populations suggests a sylvatic cycle of transmission in Argentina , which can serve as a reservoir for
humans and domestic animals . -
pubmed
A total of 1337
hepatitis B cases ( including 38 cases of co -
infection with
HCV ) were reported in Poland in 2008 , with incidence rate 3.51 per 100,000 population . -
pubmed
Compelling evidence has accumulated that histologic assessment of infiltration patterns of different host immune response components in
non - small cell lung cancer specimens helps identify different prognostic
patient subgroups . -
pubmed
CONCLUSION : Because
apathy has not yet been found to relate to meaningful
patient outcomes , and it appears that other factors such as
depression and cognition are more strongly related to quality of life than
apathy , there is not enough evidence to conclude that
apathy is a clinically meaningful
syndrome in
PD . -
pubmed
Characterization of ex vivo expanded
tumor infiltrating lymphocytes from
patients with
malignant melanoma for clinical application . -
pubmed
Clinical trials of adoptive transfer of autologous
tumor infiltrating lymphocytes ( TILs ) to
patients with advanced
malignant melanoma have shown remarkable results with objective clinical responses in 50 % of the treated
patients . -
pubmed
When autologous
tumor was available , TILs showed specific activity in all
patients tested . -
pubmed
Comparison of a commercially available repetitive - element PCR system ( DiversiLab ) with PCR ribotyping for typing of
clostridium difficile strains . -
pubmed
METHOD : Between October 2008 and December 2009 , 140
patients with
ovarian cysts undergoing laparoscopic cystectomy at Peking Union Medical Hospital were enrolled : 74 had ovarian
endometrioma with no preoperative hormonal therapy ( group A ) , 40 had
ovarian endometrioma pretreated with GnRHa ( group B ) , and 26 had non - endometriotic
cysts ( group C ) . -
pubmed
In young
rats , the sustained pressor response was associated with increased indices of renal vascular resistance ,
glomerulosclerosis and
tubulointerstitial damage as well as with a moderate inflammatory response . -
pubmed
In adult
rats , renal pathology and
inflammation was significantly less than in young
rats and was reversible . -
pubmed
Two
patients developed
ventricular fibrillation during
hypothermia , both had an acute
myocardial infarction . -
pubmed
We did not find increased risk for
bleeding complications in
patients with double platelet inhibition after PCI ( 14.3 % compared to 9.5 % without PCI , p=0.63 ) compared to those without PCI . -
pubmed
CONCLUSIONS : Under strict clinical and laboratory parameter control , induced mild therapeutic
hypothermia can be applied to most
patients after out - of - hospital
cardiac arrest with no increased risk for
arrhythmias despite significant electrocardiographic changes . -
pubmed
The validity study was performed on data from 201
patients with
acute stroke . -
pubmed
Fifty
patients with
stroke and acquired
brain injury were recruited to examine intertester and test - retest reliability . -
pubmed
In a pilot study , contrast - enhanced whole - heart coronary MRI was also acquired in four
patients with suspected
coronary artery disease with 3 - fold acceleration . -
pubmed
Hemorrhagic enterocolitis and
death in two felines (
Panthera tigris altaica and
Panthera leo ) associated with Clostridium perfringens type A. -
pubmed
Severe
hemorrhagic enterocolitis was observed in a
Siberian tiger (
Panthera tigris altaica ) and a lion (
Panthera leo ) . -
pubmed
High agreement of routine cytopathology and immunocytochemistry in
canine lymphomas . -
pubmed
The study was performed on cytological samples of 70
canine lymphomas subtyped on the basis of the updated Kiel classification system . -
pubmed
Bone resorption markers , Urinary
hydroxyproline excretion was significantly increased ( p<0.001 ) in postmenopausal
women . -
pubmed
The results from this study suggest that simple , easy , common biochemical markers can still be used to assess the bone turnover in postmenopausal
women and hence their risk of developing
osteoporosis and
fractures . -
pubmed
A novel type of selective
immunoglobulin m deficiency in a
patient with
autoimmune liver cirrhosis with recurrent
hepatocellular carcinoma : a case report and review of the literature . -
pubmed
Tests for diagnosis , specially for screening
HIV antibodies , are now fully automated ; in the same way , tests for monitoring
HIV viral load (
HIV RNA copies / ml of plasma ) , which is used for monitoring
infection and response to antiretroviral treatment , are also fully automated ; however , resistance testing , tropism determination and minor variant detection , which are used to make decisions for changing antiretroviral treatment regimens in patients failing therapy , still remain highly laborious and time consuming . -
pubmed
A case of 42 - year - old
man with
post - traumatic right hepatic artery pseudoaneurysm successfully treated by endovascular embolization with
histoacrylate glue is presented . -
pubmed
METHODS : The data of 123 consecutive
AF patients ( 74 paroxysmal and 49 persistent
AF ) who underwent RFCA between April 2009 and December 2010 in our department were retrospectively analyzed . -
pubmed
The
patients were divided into
recurrence group and no
recurrence group . -
pubmed
The ratio of
patients with HATCH & gt;= 2 in
recurrence group was higher than in non -
recurrence group [ 23.3 % ( 10/43 ) vs. 8.8 % ( 7/80 ) , P & lt ; 0.01 ] . -
pubmed
Cumulative non -
recurrence rate of
patients with HATCH score & gt;= 2 was lower than patients with HATCH score = 0 and 1 ( P & lt ; 0.05 ) . -
pubmed
BACKGROUND : Some
patients with typical (
heartburn / regurgitation ) symptoms of
gastroesophageal reflux disease (
GERD ) are refractory to proton pump inhibitor ( PPI ) therapy . -
pubmed
METHODS : Forty - four consecutive
GERD patients with
heartburn /
regurgitation refractory to high - dose PPI therapy entered a 3 - year outcome assessment following robot - assisted laparoscopic fundoplication . -
pubmed
Postoperatively ,
heartburn /
regurgitation recurred in 3
patients ; abnormal impedance - pH findings were found in two of them , and they responded to PPI therapy . -
pubmed
CONCLUSIONS : Normal reflux parameters and persistent symptom remission at 3 - year follow - up can be achieved with laparoscopic fundoplication in the majority of
patients with PPI - refractory
GERD as diagnosed by impedance - pH monitoring . -
pubmed
Autologous
rat BPCs seeded on various scaffolds were transplanted into critical - size
calvarial defects . -
pubmed
We aimed to asses whether there was any evidence for a modified radical neck dissection over a selective neck dissection by looking at the extent to which DTC
metastases to levels I and V. We performed a review of the current literature including adult and paediatric
patients who underwent a lateral neck dissection for metastatic
DTC . -
pubmed
The incidence of level V
metastases during routine level V dissection in
patients with
DTC is 20 % and the incidence of level I metastases during routine level I dissection in
patients with
DTC is 8 % . -
pubmed
Irreversible MAOIs have the potential to treat the most challenging
mood disorder patients including those with treatment - resistant
depression ,
atypical depression and
bipolar depression . -
pubmed
Exercise rehabilitation is beneficial and has become a standard of care in
patients with
systolic heart failure and
chronic obstructive pulmonary disease . -
pubmed
In recent years , several small - scale studies have demonstrated that closely supervised and monitored exercise training programs may have potential benefits in the management of stable
PAH patients , improving exercise capacity and quality of life , with an acceptable low risk of adverse events in the studied populations . -
pubmed
This review describes the emerging clinical data supporting the efficacy and safety of exercise training in
PAH patients . -
pubmed
Whole genome sequencing and phylogenetic analysis of
West Nile virus lineage 1 and lineage 2 from
human cases of
infection , Italy , August 2013 . -
pubmed
A
human outbreak of
West Nile virus ( WNV ) infection caused by
WNV lineage 2 is ongoing in northern Italy . -
pubmed
Analysis of six
WNV genome sequences obtained from clinical specimens demonstrated similarities with
strains circulating in central Europe and Greece and the presence of unique
amino acid changes that identify a new viral
strain . -
pubmed
BACKGROUND : Early age at
infection with hepatitis B virus (
HBV ) increases the risk of chronic
HBV infection . -
pubmed
PATIENTS AND METHODS : Peripheral blood samples were collected from 81
patients with
colorectal cancer , 16 with
gastric cancer and 38 healthy blood donors , as controls . -
pubmed
CONCLUSION : Multiplex - PCR - based detection of circulating
tumor cells could serve as a useful tool for the diagnosis , and monitoring of
patients with
colorectal and gastric cancer . -
pubmed
Relationship between
angina pectoris and outcomes in
patients with
heart failure and reduced ejection fraction : an analysis of the Controlled
Rosuvastatin Multinational Trial in
Heart Failure ( CORONA ) . -
pubmed
METHODS AND RESULTS : Four thousand , eight hundred and seventy - eight
patients were divided into three categories : no history of
angina and no
chest pain at baseline ( Group A ; n = 1240 ) , past history of
angina but no
chest pain at baseline ( Group B ; n = 1353 ) and both a history of
angina and
chest pain at baseline ( Group C ; n = 2285 ) . -
pubmed
CONCLUSION :
Patients with
HF -
REF and ongoing
angina are at an increased risk of
acute coronary syndrome and
HF hospitalization . -
pubmed
Migraine was ascertained in 129 ( 16 % ) of 787
adolescents at age 18 years . -
pubmed
Of the 22
adolescents , 14 ( 64 % ) had
migraine without aura and eight ( 36 % ) had
migraine with aura . -
pubmed
Infants with
colic had an almost three - fold risk ( risk ratio 2.8 , 95 % confidence interval 1.2 - 6.5 ) for adolescent
migraine without aura , but no increased risk for
migraine with aura ( 0.8 , 0.3 - 2.2 ) . -
pubmed
GOAL : The goal of the research was to determine the efficacy of a fixed combination of
tramadol and
paracetamol (
acetaminophen ) in the treatment of
pain of
patients with the advanced stage of
cancer . -
pubmed
A total of 353
patients who were treated with a fixed combination of
tramadol and
acetaminophen ( 37.5 mg and 325 mg ) at the initial dosage 3x1 tablet ( 112.5 mg
tramadol and 975 mg
acetaminophen ) for
pain intensity 4 , up to 4x2 tablets ( 300 mg of
tramadol and 2600 mg
paracetamol ) for
pain intensity 7 and 8 . -
pubmed
If the
patient during previous day has two or more
pain episodes that required a " rescue dose " of
tramadol , increased was the dose of fixed combination
tramadol and
acetaminophen to a maximum of 8 tablets daily ( 300 mg of
tramadol and 2600 mg
paracetamol ) . -
pubmed
Side effects , in the treatment of
pain with a fixed combination
tramadol and
acetaminophen , were found in 29.18 % of
patients , with a predominance of
nausea and
vomiting . -
pubmed
A novel locus on
canine chromosome 13 is associated with
cataract in the Australian Shepherd breed of domestic
dog . -
pubmed
Hereditary cataract is a common
ocular disorder in the purebred
dog population and is a leading cause of
visual impairment and
blindness in
dogs . -
pubmed
Cataract cases were defined as
dogs with
bilateral posterior cataracts , or
bilateral nuclear cataracts . -
pubmed
Using 15 bilateral
posterior polar cataract cases and 68 controls , we identified a genome - wide statistical association for
cataracts in the Australian Shepherd on
canine chromosome 13 at 46.4 Mb ( P value : 1.5 x 10(-7 ) ) . -
pubmed
Both
Staphylococcus aureus and
Staphylococcus epidermidis can form biofilms on natural surfaces or abiotic surfaces , such as medical implants , resulting in
biofilm - associated diseases that are refractory to antibiotic treatment . -
pubmed
Delirium is a robust predictor of morbidity and mortality among
critically ill patients treated in the cardiac intensive care unit . -
pubmed
Among 590
patients included , the prevalence of
CICU delirium was 20.3 % . -
pubmed
Three of these inhibitors ,
suberoylanilide hydroxamic acid (
SAHA ;
vorinostat ( ) ) ,
romidepsin (
Istodax ( ) ) and
belinostat (
Beleodaq ( ) ) , are clinically approved for the treatment of
T - cell lymphoma , while the fourth ,
panobinostat , has recently been approved for combination therapy use in certain
patients with
multiple myeloma . -
pubmed
The compounds were found to have some selectivity for
malaria parasites compared with
mammalian cells , but were not selective for
trypanosome parasites versus
mammalian cells . -
pubmed
Medial retropharyngeal lymph node ( MRLN ) mass lesions are a common cause of
cranial cervical masses in
dogs and
cats , and are predominantly due to
metastatic neoplasia , primary
neoplasia , or
inflammatory lymphadenitis . -
pubmed
A total of 31
patients were sampled , with 15 in the inflammatory
lymphadenitis group and 16 in the
neoplasia group . -
pubmed
Patients with
inflammatory lymphadenitis were more likely to be younger and present with
lethargy ( P = 0.001 ) ,
pyrexia ( P = 0.000 ) , and
neck pain ( P = 0.006 ) . -
pubmed
Patients with
inflammatory lymphadenitis were also more likely to have a
leukocystosis ( P = 0.02 ) and segmental
neutrophilia ( P = 0.001 ) . -
pubmed
A randomized comparative trial with 104 healthy premenopausal
women with
overweight /
obesity was conducted in a university setting . -
pubmed
CONCLUSION : Using both office BP and HBPM this group of Thai
patient with essential
hypertension responded well to
Losartan and Generic
Losartan . -
pubmed
They studied 301
patients with moderate
ischemic mitral regurgitation (
IMR ) undergoing coronary artery bypass grafting ( CABG ) with or without mitral repair with the primary end - point of change in left ventricular end - diastolic volume index ( LVEDVI ) at one year and multiple clinical and echocardiographic secondary endpoints . -
pubmed
Stabilization of Tnf mRNA and other cytokine transcripts in
TTP - deficient mice results in the development of a profound ,
chronic inflammatory syndrome characterized by
polyarticular arthritis ,
dermatitis ,
myeloid hyperplasia , and
autoimmunity . -
pubmed
The aims of this study were to determine the prognostic implication of UMI in
patients with stable suspected
coronary artery disease (
CAD ) and to investigate the associations of UMI with the presence of
CAD . -
pubmed
For each
patient with
UMI , the
stenosis grade of the coronary branch supplying the infarcted area was determined . -
pubmed
UMIs were present in 25 % of the
patients and 67 % of the UMIs were located in an area supplied by a coronary artery with a
stenosis grade & gt;=70 % . -
pubmed
Cohort 2 consisted of 171 subjects including
patients with
Alzheimer disease and
mild cognitive impairment and healthy volunteers . -
pubmed
Antifibrinolytics (
lysine analogues ) for the prevention of
bleeding in
people with
haematological disorders . -
pubmed
BACKGROUND :
People with
haematological disorders are frequently at risk of severe or life - threatening
bleeding as a result of
thrombocytopenia ( reduced platelet count ) . -
pubmed
METHODS : Forty - three
mCRC patients who received
cetuximab or
panitumumab between April 2012 and December 2015 were the subjects of the present study . -
pubmed
All
patients were pretreated with oral
minocycline in combination with skin treatment using moisturizer for prevention of
skin rash . -
pubmed
ORR was significantly higher in
patients with
hypomagnesemia than in those without it ( 71.4 vs 34.5 % , P = 0.048 ) . -
pubmed
Median TTF tended to be longer , though not significantly , in
patients with
hypomagnesemia than in those without it . -
pubmed
Histopathology of the filum terminale in
children with and without
tethered cord syndrome with attention to the elastic tissue within the filum . -
pubmed
PURPOSE : To compare histologically transected fila from pediatric
patients with
tethered cord syndrome (
TCS ) , with and without a low conus , with controls , focusing on collagenous and elastic tissue . -
pubmed
METHODS : Thirty fila from
patients with
TCS , including 5 where minimal cautery was used prior to filum section , were compared with fila from 27 pediatric cadavers without
TCS ( controls ) . -
pubmed
Resection guidelines that include a borderline resectable group , as well as advancements in neoadjuvant chemotherapy and radiation that improve resectability of locally advanced disease , may improve outcomes for
patients with more invasive
disease . -
pubmed
Multi - agent chemotherapy regimens
fluorouracil ,
leucovorin ,
irinotecan , and
oxaliplatin (
FOLFIRINOX ) and nab -
paclitaxel with
gemcitabine improved response rates and survival in metastatic
pancreatic cancer and are now being used in earlier stages for
patients with localized potentially resectable and unresectable disease , with goals of downstaging
tumors to allow margin - negative resection and reducing systemic
recurrence . -
pubmed
Patient selection for optimal treatment designation is currently provided by multidisciplinary
tumor boards , but biomarker discovery , in blood ,
tumors , or through novel imaging , is an area of intense research . -
pubmed
Results to date suggest that some
patients with unresectable
disease at the outset have survival rates as good as those with initially resectable
disease if able to undergo surgical resection . -
pubmed
Long - term follow - up and improved clinical trials options are needed to determine optimal treatment modalities for
patients with localized
pancreatic cancer . -
pubmed
We describe a case of successful stenting of radio induced chronic
occlusion of the right CCA in a 41 - year - old
patient with
neurological deterioration and minor
stroke due to
cerebral hypoperfusion caused by concomitant bilateral
arterial occlusions . -
pubmed
Here we studied a top QTP predator , the
saker falcon , and analysed how the transcriptome has become modified to cope with the stresses of
hypoxia and
hypothermia . -
pubmed
We did a review , restricted only to
human studies , of transparent scientific articles and sample surveys carried out and published in the period between 2001 and 2016 based on the keywords : age , aging , physical activity , physical abilities , cognitive abilities , memory and
Alzheimer ' s disease . -
pubmed
ANIMALS : Eighty client - owned
anemic , 72 donor , and 7 control
dogs . -
pubmed
All 126 pretransfusion cross - match results for the 80
anemic recipients were compatible , but 54
dogs died or were lost to follow up . -
pubmed
Nivolumab improves survival for
patients with advanced
lung cancer . -
pubmed
strains were isolated and characterized from these patients at different time points during and after ICU hospitalization , including
E. - pubmed
MATERIAL AND METHODS : The records of 46
patients treated for distal tibia physeal
fractures between 2003 and 2013 were reviewed . -
pubmed
MATERIALS AND METHODS : We used a
rat sciatic nerve injury model in which we completely transected and repaired the left sciatic nerve to evaluate the efficacy of
PEG fusion over a span of 12 weeks . -
pubmed
Thus , the use of beta - blockers may have beneficial effects on the treatment of
myocardial fibrosis in
patients with
heart failure . -
pubmed
Durable Resolution of Severe
Psoriasis in a
Patient Treated with
Pentostatin for
Hairy Cell Leukemia : A Case Report . -
pubmed
CASE REPORT : Here , we report the case of a 43 - year - old
patient with a history of extensive
psoriasis who later developed
HCL . -
pubmed
RESULTS : The
patient had achieved complete remission of both
psoriasis and
HCL after receiving intravenous infusions of
pentostatin . -
pubmed
It is worth noting that
cladribine has already been reported to treat
plaque psoriasis lesions in two
patients with
HCL and in a third
patient with
gastric marginal zone B cell lymphoma [ 1 ] . -
pubmed
CONCLUSION : We believe that
adenosine analogues constitute a promising therapeutic option for moderate to severe
psoriasis , especially for severe and refractory
psoriasis , as well as for
patients with adjacent
lymphoid malignancies . -
pubmed
Material and Method :
Patients with
TMJ ankylosis ( 8 males , 2 females ) underwent release of the
ankylosed joint by the senior author , between June 2013 and Novemeber 2015 . -
pubmed
After reconstruction of temporomandibular joint with sternoclavicular graft in the growing
child there was a significant increase in the growth of mandible which was stunned due to
ankylosis . -
pubmed
30 of these women have been enrolled in the basic group including
children with
congenital abnormalities (
CA ) . -
pubmed
More than 60 % of
patients with a PSAdt of less than or equal to 6 months had a positive F - FCH PET / CT scan for
OMD . -
pubmed
BACKGROUND :
Patients with early stage
tongue cancer do not frequently complain of
tongue pain . -
pubmed
Meniscal allograft transplantation has been used successfully to treat
patients with
postmeniscectomy syndrome , and there is early laboratory and radiographic evidence hinting at a potential prophylactic role in preventing
joint degeneration . -
pubmed
Transient Abnormalities in Masking Tuning Curve in Early Progressive
Hearing Loss Mouse Model . -
pubmed
A total of 90
outpatients of our hospital with
onychomycosis were randomised into three treatment groups : ( 1 ) standard
itraconazole pulse therapy ( 200 mg twice per day , 1 week each month for three
pulses ) ; ( 2 ) long - term
pulse therapy ( 200 mg twice per day , 1 week each month for six
pulses ) ; ( 3 ) low - dose and long - term
pulse therapy ( 200 mg / d , 1 week per month for six
pulses ) and were followed up for 15 months . -
pubmed
Escherichia coli chromosome - based T7 - dependent constitutive overexpression system and its application to generating a
phenylalanine producing
strain . -
pubmed
Integration of synthetic pathway genes into the
Escherichia coli chromosome enables generation of a plasmid - free
strain that is stable and useful for industrial applications . -
pubmed
The constructed overexpression system , a " chromosome - based T7 - dependent constitutive overexpression system " , was applied in a metabolic engineering study to generate a plasmid - free and inducer - free
phenylalanine producing
strain of
E. - pubmed
BACKGROUND / PURPOSE :
Lymphedema surgery , when integrated into a comprehensive
lymphedema treatment program for
patients , can provide effective and long - term improvements that non - surgical management alone can not achieve . -
pubmed
Surgical treatments should not be seen as a " quick fix " , and should be pursued in the framework of continuing
lymphedema therapy and treatment to optimize each
patient 's outcome . -
pubmed
Downexpression of miR-133b positively correlates with advanced clinicopathological characteristics and shorter bone
metastasis - free survival in
PCa patients . -
pubmed
Method : A retrospective analysis of 50
patients with
Eustachian tube dysfunction diagnosed . -
pubmed
Metabolomic fingerprint of coronary blood in
STEMI patients depends on the ischemic time and inflammatory state . -
pubmed
In this study we investigated whether the metabolomic analysis could identify a specific fingerprint of coronary blood collected during primary PCI in
STEMI patients . -
pubmed
Given its more convenient regimen and our results , it seems justified to use
azithromycin as the first - line treatment for
patients with
preterm premature rupture of membranes . -
pubmed
Mycobacterium abscessus felon complicated with
osteomyelitis : not an ordinary nail salon visit . -
pubmed
Mycobacterium abscessus is an environmental organism that has been implicated in
pulmonary and extrapulmonary infections . -
pubmed
Pressure
pain sensitivity in
patients with traumatic first - time and recurrent
anterior shoulder dislocation : a cross - sectional analysis . -
pubmed
Methods This was a cross - sectional analysis of baseline data from a randomized controlled trial including 34
patients with first - time
ASD [ 82 % male , mean ( SD ) age 26 ( 7 ) years ] and 22
patients with recurrent
ASD [ 96 % male , mean ( SD ) age 25 ( 5 ) years ] . -
pubmed
Patients were assessed as follows : ( 1 ) assessment of local and distant pressure
pain sensitivity evaluated by pressure
pain thresholds ( PPTs ) using a handheld algometer on mm . -
pubmed
PURPOSE : The aim of this study was to assess the functional and clinical results of
patients who underwent ACL reconstruction surgery and were divided into subpopulations related to
ACL - associated lesions and focused on
ALL - associated lesion . -
pubmed
In 42
patients out of 62 ( 68 % ) ,
ALL lesion was evident . -
pubmed
RESULTS : The overall re -
injury rate in our cohort of
patients was 4.8 % with a smaller but not a significant difference between the two groups . -
pubmed
CONCLUSION : The additional
ALL reconstruction / repair surgery should always be considered in
patients with evident
ALL tear at the preoperative MRI . -
pubmed
Evaluation of
Neospora caninum serodiagnostic antigens for
bovine neosporosis . -
pubmed
Abortion and
reproductive failure caused by
Neospora caninum infection has a dramatic negative economic impact on the
cattle industry . -
pubmed
caninum antigens in relation to
abortion in
cattle . -
pubmed
METHODS : 60 laryngectomized
patients with
VP and 30 controls were included in the study . -
pubmed
RESULTS : A total of 7198 ESs were deployed endoscopically in hospitalized
patients with
dysphagia . -
pubmed
CONCLUSION : In the preceding decade , ES placement for hospitalized
patients with
dysphagia has increased , driven largely by an over 8 - fold rise in stent placement for benign indications . -
pubmed
Polycystic ovary syndrome (
PCOS ) in adolescent
girls is usually related to hepato - visceral fat excess and
insulin resistance , and associates with comorbidities such as
type 2 diabetes . -
pubmed
RESEARCH DESIGN AND METHODS : We studied 51 adolescent
patients with
PCOS and 21 age - matched healthy controls . -
pubmed
Thirty - one adolescent
patients with
PCOS under SPIOMET or
oral contraception - based treatment were also studied . -
pubmed
Human immunodeficiency virus type 1 ( HIV-1 ) establishes lifelong infections in
humans , a process that relies on its ability to thwart innate and adaptive immune defenses of the host . -
pubmed
IMPORTANCE People living with
HIV can experience accelerated aging and the development of
neurological disorders . -
pubmed
The purpose of this study was to investigate the cardioprotection offered by the
iron - chelating agent
deferiprone (
DFP ) in a
porcine AMI model by evaluating
hemorrhage neutralization and subsequent
cardiac remodeling . -
pubmed
Impaired follicular development and
endocrine disorders in female
rats by prepubertal exposure to toxic doses of
cadmium . -
pubmed
Chemoradiation in elderly
patients with
glioblastoma from the multi - institutional GBM - molRPA cohort : is short - course radiotherapy enough or is it a matter of selection ? -
pubmed
BACKGROUND : The optimal radiotherapy regimen in elderly
patients with
glioblastoma treated by chemoradiation needs to be addressed . -
pubmed
HBV+ cohort were younger ( p<0.001 ) but just as likely to have
diabetes , be on dialysis , and have similar smoking status compared to
HBV- cohort . -
pubmed
As a special subpopulation , pregnant
women are more susceptible to nanoparticle ( NP)-induced
toxicity . -
pubmed
Early diagnosis and genetic testing of
FH suspects is critical for improved prognosis of affected
individuals as lipid lowering treatments are effective in preventing
CHD related morbidity and mortality . -
pubmed
Methods The study included 311
patients with invasive
BC diagnosed at the Department of Pathology , School of Medicine in Sarajevo , Bosnia and Herzegovina , during the period 2015 - 2019 . -
pubmed
OBJECTIVE : To explore the genetic basis for a
child with
ichthyosis . -
pubmed
Patients undergoing PD for biliary , duodenal or
pancreatic diseases are randomly assigned to the
TXA or placebo group . -
pubmed
Patient characteristics , immediate versus delayed reconstruction , type of flap used , indication for secondary augmentation as well as perioperative and
postoperative complication including flap or implant loss were reviewed and analyzed . -
pubmed
Postoperative surgical site
infection occurred in a total of 4
patients ( 17 % ) with 3
patients requiring explantation of a total of 4 implants . -
pubmed
In a subgroup of
patients affected with novel
Coronavirus disease (
COVID-19 ) ,
tocilizumab has also increased the survival rate . -
pubmed
We present the case of a 31 - years - old Caucasian
patient who experienced an almost asymptomatic
Severe Acute Respiratory Syndrome Coronavirus (
SARS - CoV-2 ) infection during treatment with
tocilizumab , which was continued due to the very high risk of
relapses of the patient . -
pubmed
This study aims to establish an ELISA kit specifically for detecting UHp in urine samples of
patients with
diabetes and
DKD . -
pubmed
This kit was used to detect UHp in 246 healthy
individuals and 83
patients with
type 2 diabetes (
T2D ) . -
pubmed
METHODS : Data of adult
patients with
RA ,
PsA or
axSpA who had received reference
etanercept were retrospectively analysed . -
pubmed
RESULTS : Data of 84
patients were available ( 44 RA , 25
axSpA and 15
PsA patients ) , of whom 24 had been informed about the planned switch ( 28.5 % ) . -
pubmed
Seven
patients were lost to follow - up , and six
patients discontinued due to inefficacy or
ADE . -
pubmed
RESULTS : Eleven of 199
patients with
GC who achieved ypT0N0 status after
NAC were classified as the pCR group in this study . -
pubmed
Effectiveness of Hearing Aid Treatment in
Patients with
Chronic Tinnitus : Subscale Evaluations Using the Tinnitus Functional Index and Factor Analysis . -
pubmed
A total of 21
patients with
chronic tinnitus were included . -
pubmed
A method is described for comparing narcotic analgesics and adjuvants in
patients with
terminal cancer . -
pubmed
Egg production dropped after hens were inoculated with
fowlpox virus originally isolated from a natural mild
infection . -
pubmed
[ 3H ] GABA binding in brains from
Huntington ' s chorea patients : altered regulation by phospholipids ? -
pubmed
Binding sites for
tritum - labeled
gamma - aminobutyric acid (
GABA ) in cerebellar cortex of
Huntington ' s chorea patients have an increased affinity but unaltered maximum capacity as compared to binding sites in tissue from control
patients . -
pubmed
Limb - saving resection has become a valid alternative to amputation in carefully selected
patients with
bone tumors . -
pubmed
The samples were obtained from 12
patients with suspected
intracranial disease . -
pubmed
Prognostic significance of lymph node histology in
patients with
squamous cell carcinoma of the larynx , pharynx , or oral cavity . -
pubmed
Metastases occurred much more frequently in
patients whose nodes showed immunologic activity than in those whose did not . -
pubmed
X - ray therapy of selected
odontogenic neoplasms in the
dog . -
pubmed
Macrophage function and host resistance against
infection with
Toxoplasma gondii . -
pubmed
The role of macrophages on the course of an
infection with
Toxoplasma gondii has been examined . -
pubmed
The functional blockade of macrophages by dextran sulfate or
carbon particles did not result in a higher susceptibility of
mice to the lethal primary
infection with
T. - pubmed
Thus in vivo macrophages apparently do not play an essential role as effector cells as they do in
infections with other obligate intracellular infective organisms such as
Listeria monocytogenes . -
pubmed
gondii infection , since
death occurred earlier in splenectomized
mice than in control animals . -
pubmed
Data are presented on the state of the intrahepatic blood flow and the absorption - excretory capacity of the liver in 221
patients with
acute myocardial infarction . -
pubmed
The agents were tested for
cytotoxic activity against
P388 mouse leukemia cells . -
pubmed
None of the target molecules were as potent against
Escherichia coli as they were against the
tumor cells . -
pubmed
To evaluate the efficacy of plasma perfusion as a liver - assistance system , 17
patients with
hepatic failure were treated with a total 37 sessions of plasma perfusion and 43 sessions of plasma exchange . -
pubmed
A case of
human endocarditis due to
Streptococcus suis in North America . -
pubmed
We thus prospectively examined 275
children with
epilepsy ; in particular , we analyzed the prognostic role of the EEG . -
pubmed
In 107
children the anticonvulsive therapy was discontinued , leading to a
relapse rate of 27 % . -
pubmed
We reviewed scans from 500
patients who had screening CT examinations of the
sinuses for preendoscopic evaluation of
inflammatory sinonasal disease to better define an optimal imaging protocol . -
pubmed
A 62 - year - old
man with
rheumatoid arthritis developed
jaundice while taking
piroxicam . -
pubmed
The
patient 's
jaundice and all other liver function abnormalities normalized 4 months after he discontinued taking
piroxicam . -
pubmed
Glucose partitioning in the pregnant
ewe : effects of
undernutrition and exercise . -
pubmed
Clinical manifestations of gastrocnemius
hematoma in a 64 - year - old
man with local
swelling ,
pain and
tenderness that was aggravated by passive dorsiflexion of the ankle joint , mimicked
deep vein thrombosis . -
pubmed
In experimental
animals beta - blockers have been found to reduce spontaneous motor activity , to counteract isolation- , lesion- , stimulation- and
amphetamine - induced
hyperactivity , and to produce slow - wave and paradoxical
sleep disturbances . -
pubmed
[
Antibiotic - associated colitis and
Clostridium difficile ] . -
pubmed
Laser Doppler flowmetry ( LDF ) is a new and noninvasive technique for skin blood flow measurement and has been used pre - operatively in 25
patients undergoing amputation for
vascular disease and in five normal controls . -
pubmed
One
patient had mild
paresis of the lower extremities . -
pubmed
Effect of
cyclosporine on immunologically mediated
diabetes in nonobese
diabetic mice . -
pubmed
Spontaneous
diabetes in
NOD mice has an immunologically mediated cause and is a T cell - dependent process . -
pubmed
When
diabetic NOD
mice are grafted with cultured BALB / c islet tissue , the islet graft is destroyed by disease
recurrence in the graft . -
pubmed
Data presented here show that
cyclosporine is ineffective in controlling disease
recurrence in the islet graft transplanted to actively
diabetic animals . -
pubmed
Nine eyes of nine
patients affected by
retinal detachment with
macular hole were treated with pneumoretinopexy and postoperative positioning . -
pubmed
The prevention of
postoperative pain in
children who had undergone tonsillectomy was investigated in a double - blind trial . -
pubmed
Lung biopsies from four
children and two adults with
idiopathic pulmonary haemosiderosis have been examined by transmission electron microscopy . -
pubmed
The carrageenin
rat paw
edema was dose - dependently inhibited by i.v . -
pubmed
In contrast , no antiinflammatory activity of
desferrioxamine could be seen in
rat adjuvant
arthritis , a model of subacute and chronic
inflammation . -
pubmed
Magnetic resonance ( MR ) imaging of the cervical spine was employed in 18
patients with
rheumatoid arthritis and suspected cervical involvement . -
pubmed
Fifteen
patients had symptoms referable to the cervical spine , and seven had
neurologic deficits . -
pubmed
Cervical radiographs were available for all
patients ;
bone erosion was evident in 14 , subluxation in 17 , and no abnormalities in one . -
pubmed
MR imaging demonstrated indentation or abnormal signal in the caudal brain stem and/or cervical spinal cord in ten
patients , including the seven with related
neurologic deficits ; discrete indentation or distortion of the dura without visible morphologic effect on the underlying neuraxis was observed in five other
patients . -
pubmed
In all
patients with
neurologic symptoms , cord or brain - stem abnormalities were seen on MR images . -
pubmed
MR imaging therefore appears to provide valuable information regarding the status of the spinal cord and dura in
patients with
rheumatoid arthritis . -
pubmed
PISA -- a new noninvasive method for early detection and quantification of
ischemia in
hypertensive patients . -
pubmed
This method was therefore used in 25 healthy
individuals , 20
patients with documented
ischemic heart disease and 50
hypertensive patients ( duration 1 - 6 years ) with no
end - organ disease in order to determine if these
patients have
myocardial ischemia and/or
infarction . -
pubmed
All 20
patients with documented
ischemic heart disease had phase variant signature and had high PISA index in two or more leads . -
pubmed
Twenty - nine of the 50
hypertensive patients were found to have phase - variant ( abnormal ) PISA signatures and their PISA index was beyond the upper limit of normal PISA range ( mean + 3S.D. -
pubmed
Recovery of VEP delay in
patients with
vitamin B12 deficiency . -
pubmed
Two
patients with a
neurologic syndrome of vitamin B12 deficiency and delayed Visual Evoked Potentials are reported . -
pubmed
[ Response of
rat fetal adrenal glands to an
aggression in different experimental conditions ; effect of
nembutal ] . -
pubmed
[ Effect of the house climate and hygiene on production and the incidence of
respiratory and intestinal disorders in
pig breeding ] . -
pubmed
Amebic cellulocutaneous invasion by
Naegleria aerobia with generalized
visceral lesions after subcutaneous inoculation : an experimental study in
guinea pigs . -
pubmed
Data obtained from the naturally resistant
rat that had been immunized with both the Belton - Strange protective antigen and live vaccine demonstrated the role of " toxins " in terminal
anthrax . -
pubmed
Facilitation and antagonism of kindled
seizure development in the limbic system of the
rat . -
pubmed
To study the relative contribution of positive and negative transfer during the kindling of motor
seizures , we electrically stimulated the septal area and entorhinal cortex in
rats according to two different stimulation paradigms . -
pubmed
Thirteen of 14
animals exhibited generalized
convulsions from one site only . -
pubmed
Eight
patients who had
facial nerve neuromas were examined , and the radiographic findings are reported . -
pubmed
Radiologic imaging frequently permits a correct preoperative diagnosis and accurate definition of the extent of
facial nerve neuromas , assessments that are important for proper
patient management . -
pubmed
Comparative enzyme - inducing effects of
chlorpromazine and
fluphenazine therapies in
psychotic patients . -
pubmed
Antipyrine elimination kinetics were measured in
psychotic patients receiving either long - term
chlorpromazine or
fluphenazine decanoate therapy and in non - medicated control
subjects . -
pubmed
In addition , it is suggested that
bovine cervical mucus could be developed as a possible substitute for
human cervical mucus in cases of
infertility due to deficient endogenous mucus . -
pubmed
Appendico - vesical fistula and
persistent urachus in a
patient with
hematuria . -
pubmed
A 35 - year - old
man had been treated with
sulfamethizole on 6 occasions because of recurrent
urinary tract infections . -
pubmed
Dihydroergotoxine administration shortened the latency of
allylglycine - and
picrotoxin - induced
convulsions in
rats and increased the incidence of
convulsions elicited by
picrotoxin , i.e. -
pubmed
A localized
atheromatous plaque was induced in
rabbits after transmural electrical stimulation of the carotid and a
cholesterol - rich diet ( 1.33 %
cholesterol ) for 4 weeks . -
pubmed
During the experimental period , all
rabbits showed similar
weight gain , regardless of the treatment . -
pubmed
Seventeen
patients who received
radioiodine ( 131I ) therapy for
Graves ' hyperthyroidism had serial blood samples taken before therapy and after therapy for a period of at least 1 year . -
pubmed
Seven
patients were euthyroid , and four
patients were
hyperthyroid . -
pubmed
Four
patients out of 11 developed
hypothyroidism and six of the 11 developed
euthyroidism . -
pubmed
A decrease in TBII was observed in three
patients who developed
hyperthyroidism . -
pubmed
Of these , four developed
hypothyroidism and three developed
euthyroidism , whereas three of the four
patients who had a marked decrease in TPOAb developed
hyperthyroidism . -
pubmed
Four
mouse B16 melanoma subclones (
G3.15 ,
G3.5 ,
G3.12 and
G3.26 ) exhibit progressively greater growth capacity in vitro and in vivo . -
pubmed
Interest in tick - borne pathogens has been enhanced by the emergence of
Lyme disease and , more recently ,
human and animal
ehrlichioses . -
pubmed
CONCLUSION : It appears that conservative treatments contributed to the decreased survival of older
ovarian cancer patients . -
pubmed
This case suggests that we must consider the presence of
coronary vasospasm even in
patients with clinically - supposed
effort angina , to be possibly due to
vasospasm occurring in anomalous coronary arteries . -
pubmed
MRI findings in an
individual at risk for
familial Alzheimer ' s disease . -
pubmed
Anthroponotic cutaneous leishmaniasis in Kabul , Afghanistan : the high susceptibility of
Phlebotomus sergenti to
Leishmania tropica . -
pubmed
Causal relationship between occlusive lesions of the coronary artery and
myocardial fibrosis in arteriosclerotic
rabbits -- differences between
cholesterol - fed and heritable
hyperlipidemic rabbits . -
pubmed
To investigate the causal relationship between lesions of either the proximal large or the distal small coronary arteries and
myocardial fibrosis , the hearts and the aortas of 99
cholesterol - fed
rabbits with either intermittent or continuous
hyperlipidemia for 8 months or more , 44 Watanabe - heritable
hyperlipidemic ( WHHL )
rabbits and 20 normal
rabbits were studied histologically . -
pubmed
The size and location of the
myocardial fibrosis correlated closely with the almost completely occlusive distal small coronary artery which mainly consisted of macrophages ,
necrosis and
calcification but did not correlate with the maximum %
stenosis of the large proximal subepicardial coronary arteries in the
cholesterol - fed -
rabbits . -
pubmed
Myocardial
fibrosis and almost completely occlusive lesions of the distal small coronary arteries were very rare in the WHHL
rabbits , and the maximum %
stenosis of the proximal coronary artery and
aortic lesions in the WHHL
rabbits tended to be greater than those in the
cholesterol - fed
rabbits . -
pubmed
Thus , we are still not certain as to whether or not , the
organic stenosis of the subepicardial coronary artery is responsible for
myocardial fibrosis in WHHL -
rabbits . -
pubmed
In conclusion , a causal relationship was observed between
myocardial fibrosis and the occlusive lesions of the distal small coronary arteries in
cholesterol - fed
rabbits , while the
arteriosclerotic lesions of the small coronary artery in
cholesterol - fed
rabbits completely differed from those observed in WHHL -
rabbit . -
pubmed
Enhancement of gene therapy specificity for diffuse
colon carcinoma liver metastases with recombinant
herpes simplex virus . -
pubmed
OBJECTIVE : The authors determined whether a recombinant
herpes simplex virus ( HSV ) vector could destroy
human colon carcinoma cells in vitro and whether the vector would selectively replicate in
colon carcinoma liver metastases but not surrounding hepatocytes in vivo . -
pubmed
Further investigation of
HSV - based vectors as oncolytic agents for liver
metastases is warranted . -
pubmed
Hemianopic visual field defects in
children with intracranial shunts : report of two cases . -
pubmed
CLINICAL PRESENTATION : Two cases are described in which
homonymous hemianopsia resulted from unsuspected movement of the shunt catheter in growing
children . -
pubmed
In one male
patient , the catheter tip impaled the optic tract , and in the other male patient the shunt became embedded in the midbrain tegmentum and
shunt failure led to compression of the posterior cerebral artery . -
pubmed
Some
patients with
chronic hepatitis C develop liver / kidney microsome type 1 antibodies . -
pubmed
Serum from 24
patients with markers of
hepatitis C infection and liver / kidney microsome type 1 antibodies were tested by immunoblotting with
human liver microsomal proteins . -
pubmed
Evaluation of
glomerular lesion and abnormal urinary findings in OLETF
rats resulting from a long - term
diabetic state . -
pubmed
Otsuka Long - Evans Tokushima Fatty ( OLETF )
rats have been established as an
animal model in which
non - insulin - dependent diabetes mellitus develops spontaneously . -
pubmed
We examined the renal histopathology and the urinary findings serially in OLETF
rats and compared these findings with findings in age - matched Long - Evans Tokushima Otsuka ( LETO )
rats as a control
strain . -
pubmed
Accompanying the development of
hyperglycemia was an increase in the amount of
albuminuria in OLETF
rats from 18 weeks of age . -
pubmed
Mesangial lesions progressed to
mesangial sclerosis , and
exudative lesions were found in OLETF
rats from 36 weeks of age . -
pubmed
The anionic charge of glomerular basement membrane ( GBM ) , measured by
polyethyleneimine grain density , demonstrated that the lower grain density in OLETF
rats when compared with that in LETO
rats became more evident with an increase in the amount of
albuminuria . -
pubmed
Therefore , the defect in the charge - selective property found in OLETF
rats might be one of the causes of
albuminuria . -
pubmed
The
GBM became thickened in elderly OLETF
rats as compared with that in age - matched LETO
rats . -
pubmed
Given these findings , we consider the OLETF
strain of
rats to be an interesting
animal model for studying the relationship between
diabetes and renal involvement , because the
glomerular abnormalities and massive
albuminuria found in OLETF
rats were results of a long - term
diabetic state . -
pubmed
Retropharyngeal lymphadenopathy in
patients with
nasopharyngeal carcinoma : a computed tomography - based study . -
pubmed
METHODS : From January 1989 to December 1991 , 364
patients with newly diagnosed
nasopharyngeal carcinoma without distant metastasis had a baseline CT performed . -
pubmed
No significant differences in
relapse free survival rates , local control rates , lymph node control rates , or distant failure rates were observed between
patients with or without
retropharyngeal lymphadenopathy after adjusting for T and N classifications . -
pubmed
In 134
patients with clinical N0 disease ,
retropharyngeal lymphadenopathy was found in 21
patients , whereas 113 had no evidence of
retropharyngeal lymphadenopathy . -
pubmed
It was shown on one generation of
rats that
CBL at dose of 1 g and 10 g per 1 kg of body mass had no an embryotoxic ,
gonadotoxic and
teratogenic effects . -
pubmed
Normotensive
Wistar - Kyoto ( WKY ) rats responded to BilCAT like
Sprague - Dawley rats , whereas spontaneously
hypertensive rats ( SHR ) exhibited an exaggerated vasodepressor response to BilCAT ( -51 + /- 3 mmHg ) without increasing either UNaV or
GFR . -
pubmed
Healthy subjects ( n = 20 ) and
hypertriacylglycerolemic patients ( n = 6 ) were given a placebo (
olive oil , OO ) or a
fish - oil concentrate ( FOC ; 41 %
eicosapentaenoic acid and 23 %
docosahexaenoic acid ) in two , independent , randomized , blind trials . -
pubmed
OBJECT : The purpose of this study was to determine whether intrinsic neuronal properties and synaptic responses differed between interictally active and inactive tissue removed in neocortical resections from
patients undergoing surgical treatment for
epilepsy . -
pubmed
METHODS : Whole - cell patch recordings were performed in layer 2 or 3 and layer 5 pyramidal cells in neocortical slices obtained from tissue surgically removed from
patients for the treatment of medically intractable
seizures . -
pubmed
Therapeutic and prognostic implications of
peripheral blood lymphopenia in
patients with
Hodgkin ' s disease . -
pubmed
Patients with
Hodgkin ' s disease (
HD ) are known to have
peripheral blood lymphopenia , but the prognostic significance of this observation and its implication on immune therapy remain controversial . -
pubmed
We determined the peripheral blood lymphocyte ( PBL ) counts and their subsets of 238 newly diagnosed
patients with
HD referred to our institution , and the quantitative changes of B , T , and natural killer cells were correlated with the
patients ' clinical variables . -
pubmed
In this study , the decline in total PBL count or in its subsets in
HD patients did not correlate with shorter disease free survival . -
pubmed
Thus , strategies to improve lymphocyte functions in
HD patients should continue to be explored therapeutically . -
pubmed
In a patient with
chronic neuroborreliosis , we show that this strategy leads to the identification of potentially relevant T - cell targets derived from both
Borrelia burgdorferi and the host . -
pubmed
Those
strains from the outbreak of
digestive disease belonged to
serotype 050 : H11 and had a thermostable toxin . -
pubmed
The first case of
infectious neurologic syndrome with
Plesionomas shigelloides etiology reported in Cuba was described ; the
strain corresponded to
serotype 050 : H11 . -
pubmed
Six neurochemicals associated with a
decrease in blood pressure were measured in
humans ( n=18 ) and
dogs ( n=18 ) before and after positive interaction . -
pubmed
Altered activities of
rat brain metabolic enzymes in electroconvulsive
shock - induced
seizures . -
pubmed
The aim of this work was to investigate the influence of a single or repeated ECS - induced
seizures on
rat brain metabolism . -
pubmed
OBJECTIVES : To study the prophylactic efficacy of
lithium administered every second day to
patients with
bipolar disorder or recurrent
unipolar depressive disorder . -
pubmed
Participation in the study was conditional on the
patient having been in prophylactic
lithium treatment for the preceding 2 - year period and having been free of
depressive or
manic phases during the preceding 6 months . -
pubmed
RESULTS : Forty - seven
patients , 42 with a diagnosis of
bipolar disorder and five with a diagnosis of recurrent
unipolar depressive disorder , participated in the study . -
pubmed
The remaining nine
patients had
recurrences , a number not differing from the 16
patients in the same group of 47
patients who , during the 2 - year period preceding the study , had
recurrences . -
pubmed
The mean 12 - h standard serum
lithium concentration was lower in the
patients who had
recurrences than in those who stayed euthymic . -
pubmed
[ A case of
mucoid impaction of bronchi (
MIB ) due to
Schizophyllum commune ] . -
pubmed
Over the past 20 years at my institution , 71
patients with invasive necrotizing
aspergillosis have been encountered ; 42 have shown central nervous system ( CNS ) involvement by autopsy ( 40 ) or surgical biopsy ( 2 ) . -
pubmed
During the same period , single cases of
cerebritis caused by morphologically similar fungi (
Pseudoallescheria boydii [
Scedosporium apiospermum ] ,
Scedosporium inflatum ,
Chaetomium sp ) were identified and were indistinguishable from CNS
aspergillosis clinically and pathologically . -
pubmed
Pupil signs of
sympathetic autonomic neuropathy in
patients with
type 1 diabetes . -
pubmed
We investigated pupil responsiveness to directly and indirectly acting sympathomimetics in
type 1 diabetic patients with and without long - term complications , defined as
cardiac autonomic neuropathy (
CAN ) ,
peripheral sensomotor neuropathy ,
retinopathy , and
nephropathy , and in healthy subjects . -
pubmed
RESEARCH DESIGN AND METHODS : A total of 47 randomly chosen
type 1 diabetic patients and 20 healthy
subjects were selected for this study . -
pubmed
Patients were divided into groups determined by whether they had long - term
diabetic complications . -
pubmed
CONCLUSIONS : Our results clearly show that sympathetic denervation does exist in the pupil of
diabetic patients and that it can be rapidly assessed using the
cocaine test . -
pubmed
The effects of Biopin ( ointment containing pine resin ) used in the treatment of
burns ,
wounds , and pyoinflammatory processes on cell composition of the
wound surface ( smears ) and granulation tissue were studied on
rats . -
pubmed
We report a case of DeBakey IIIb type
dissecting aneurysm with
adrenal myelo - lipoma in a 50 - year - old
woman . -
pubmed
The
patient was referred to our hospital for severe
back pain with severe
hypertension . -
pubmed
Adaptive changes related to medication treatment of
ADHD : listening to parents of
children in clinical trials of a novel nonstimulant medication . -
pubmed
Increased intracranial blood flow volume in a
preeclamptic woman with postpartum
photophobia . -
pubmed
We studied the changes in intracranial blood flow volume using a new color Doppler ultrasonographic assessment in a
preeclamptic woman with
photophobia . -
pubmed
Specimens were derived from either the hippocampus or the temporal lobe cortex and from the
tumor - free approach corridor tissue of
patients with
brain tumors . -
pubmed
Does
right hemisphere damaged patients ' impaired performance on a sentence insertion task indicate a syntactic or a lexical level deficit ? -
pubmed
There is no cross - reactivity between
mono - bactams or
carbapenems with
beta - lactams , and these drugs may be used safely in
patients with
anaphylactic reactions to
beta - lactams . -
pubmed
A case report is presented of an
infant with
jejunal atresia and
hyperbilirubinemia with diagnosed
pancreaticobiliary maljunction without
choledochal dilatation . -
pubmed
Infection rates of digenetic trematodes in the snails were 6.9 % in
P. - pubmed
A rare case with
Endamoeba histolytica in the
ascites fluid and liver tissue ] . -
pubmed
Axon dystrophy in clinically normal
dogs . -
pubmed
We aimed to evaluate the interdomal region in four fresh
cadavers and 24
patients who underwent open rhinoplasty , since the nasal tip area is the most difficult part of the rhinoplasty . -
pubmed
Preclinical data from chimpanzees and studies in
hepatitis B virus / hepatitis C virus (
HCV ) coinfected transplant recipients suggest prophylactic
HCV antibody therapy may have a role in the prevention of
HCV recurrence . -
pubmed
Preemptive antiviral therapy , started within the first 4 weeks posttransplantation and prior to the onset of clinical
signs and symptoms , is effective in some
patients ( 5 - 33 % ) and is not associated with an increased risk of acute rejection . -
pubmed
Iron deficiency anemia as the only sign of
infection with
Helicobacter pylori : a report of 9 pediatric cases . -
pubmed
Recently , an association between
Helicobacter pylori (
HP ) and
iron deficiency anemia (
IDA ) was proposed . -
pubmed
The authors evaluated the results of a medial approach for the corrective osteotomy of 14 consecutive
children ( mean age 8.4 years ) with
cubitus varus . -
pubmed
Clinical follow - up was performed on 151
patients ( 93 % ) , to identify the incidence of cardiac and neurological events and freedom from late
death . -
pubmed
[ Effect of cardiopulmonary bypass on selected neutrophil functions in
children with cyanotic
congenital heart disease ] . -
pubmed
Children suffering from cyanotic
congenital heart disease (
CCHD ) have been assumed to have a deficiency in their defence mechanisms . -
pubmed
MATERIALS AND METHODS : 23
infants and
children with
congenital heart disease , scheduled for primary corrective surgical repair ; were enrolled . -
pubmed
In severely burned
rats ,
hyperemia ,
edema and other pathological
injuries occur in the intestinal mucosa . -
pubmed
In a randomised controlled trial , 92
patients with
adhesive capsulitis received either high - grade mobilisation techniques or low - grade mobilisation techniques and were followed for one year . -
pubmed
METHODS : In the present study , using leukapheresis products from 10
cancer patients , we validated an elutriation technology for large - scale clinical grade production of monocyte - derived DC . -
pubmed
Prostate cancer remains the most common noncutaneous
human malignancy , and the second most lethal
tumor among men . -
pubmed
A 62 - year - old
woman , who had been diagnosed with
sarcoidosis 3 years previously because of abnormalities on chest X - ray radiophotographs and lymph node pathology , was admitted to our hospital for the evaluation of
proteinuria and microscopic
hematuria . -
pubmed
Cytomegalovirus is usually transmitted by direct
human - to -
human contact through vertical or horizontal routes . -
pubmed
In the surgical literature , intestinal
CMV - infected cells in infants have prevalently been associated with
neonatal necrotizing enterocolitis , and only very few cases of primary
CMV infection of the gastrointestinal tract of surgical interest in immunocompetent neonates have been reported . -
pubmed
The authors present the cases of two
children who developed relatively uncommon adverse effects to new anticonvulsant medications , including
metabolic acidosis with
topiramate and
hyponatremia with
oxcarbazepine . -
pubmed
In one of our two
patients , intraoperative
acidosis related to
topiramate was noted . -
pubmed
In our second
patient ,
hyponatremia and
status epilepticus resulted from therapy with
oxcarbazepine . -
pubmed
By means of preimplantation genetic diagnosis (
PGD ) , we now can screen
human embryos in vitro for
aneuploidy before transferring the embryos to the uterus . -
pubmed
Also ,
human placental cytotrophoblasts ( CTBs ) at the fetal - maternal interface acquire
aneuploidies as they differentiate to an invasive phenotype . -
pubmed
Synergistic muscle activation during maximum voluntary contractions in
children with and without
spastic cerebral palsy . -
pubmed
We examined muscle recruitment patterns in
children with
cerebral palsy (
CP ) and comparison
children without
CP under conditions of maximum voluntary contractions . -
pubmed
Three groups of
children participated in the study : ( 1 ) 12
children with
diplegic CP ( eight
males , four
females ; age range 4 - 10 y , mean age 7 y [ SD 2 y 4 mo ] ) ; ( 2 ) six
children with
hemiplegic CP ( four
males , two
females ; age range 5 - 10 y , mean age 7 y 4 mo [ SD 2 y ] ) ; and ( 3 ) 13 comparison
children with normal motor function ( seven
males , six
females ; age range 4 - 11 y , mean age 7 y 2 mo , [ SD 2 y ] ) . -
pubmed
The
children with
CP were classified according to the Gross Motor Function Classification System : eight were Level I , five were Level II , four were Level III , and one was Level IV . -
pubmed
Children with
CP more frequently activated a muscle other than the intended prime mover first , compared with the comparison children , especially when the prime mover was a distal muscle . -
pubmed
In vitro
chromosome aberration tests using
human dental pulp cells to detect the carcinogenic potential of chemical agents . -
pubmed
To examine if
human dental pulp cells are useful for assessing the carcinogenic potential of chemical agents , we cultured
human dental pulp cells from
adults and studied the ability of chemical agents known to be carcinogenic to induce
chromosome aberrations in these cells . -
pubmed
Next , we examined if
chromosome aberrations were induced by exposure of
human dental pulp cells ( designated here as
D824 cells ) at seven to nine passages to chemical agents with carcinogenic activity . -
pubmed
Statistically significant increases in the frequencies of
chromosome aberrations were induced in
D824 cells treated with a direct - acting carcinogen ,
mitomycin C , for 3 h.
Chromosome aberrations were also induced at statistically significant levels in
D824 cells treated with an indirect - acting carcinogen ,
cyclophosphamide , for 2 h in the presence of exogenous metabolic activation with
rat liver postmitochondrial supernatant . -
pubmed
Although the reliability of
chromosome aberration tests using
human dental pulp cells remains to be validated by studying the ability of various other chemical agents with or without carcinogenic activity to induce
chromosome aberrations , this
chromosome aberration test system may be useful for carcinogenic risk assessment in the target cells . -
pubmed
Classic treatments of
osteogenesis imperfecta for
children and adults include rehabilitation therapy and orthopedic surgery . -
pubmed
However , further studies are needed to demonstrate an effect on
fracture rate in
children and adult
patients . -
pubmed
MATERIALS AND METHODS : Six
patients with biochemical evidence of an
insulinoma underwent pre - operative localisation studies and selective arterial
calcium injection ( SACI ) . -
pubmed
Those three
patients , in whom magnetic resonance imaging and/or endosonography could localise the
tumors pre - operatively , underwent laparoscopic surgery while the remaining three
patients underwent open surgery . -
pubmed
We report the case of a
patient with unilateral
AEC that was followed up over a 3 - year period and also discuss the role played by the right hemisphere in this disorder . -
pubmed
A few days after the
stroke the
patient reported the inability to close his left eye on command , although he was still able to blink spontaneously and the blink and visual threat reflexes were preserved . -
pubmed
PURPOSE : We report the feasibility of laparoscopic ipsilateral ureteroureterostomy for
duplication anomalies of the urinary tract in
infants and
children , and the short - term results in 6
patients . -
pubmed
PURPOSE : To evaluate the results of lacrimal probing in
children at or older than 1 year of age with
congenital nasolacrimal duct obstruction . -
pubmed
MATERIALS AND METHODS : Fifty eyes of 38
children ( 24
males , 14
females ) with
congenital epiphora who underwent nasolacrimal duct probing were evaluated in a prospective study . -
pubmed
Residual
epiphora was observed in 6 eyes of 4
patients ( 12 % ) . -
pubmed
Age of the
patient , gender , the frequency of
epiphora before probing and the unilaterality or bilaterality of
epiphora did not correlate with the success of probing ( p & gt ; 0.05 ) . -
pubmed
Unsuccessful probing may result from the selection of
nonmembranous obstructions rather than the increased age of the
patients . -
pubmed
The aim of the present study was to assess prospectively
patients ' response to facet joint injection performed for
lumbar back pain , and to check if it correlates with the response predicted by the Helbig and Lee scoring system . -
pubmed
Fifty - seven
patients who had facet joint injections for mechanical
low back pain unresponsive to medical treatment , were followed - up . -
pubmed
OBJECTIVE : The aim of this study was to extend a previous 2 - week assessment of a probiotic - prebiotic complex in
patients with
irritable bowel syndrome (
IBS ) . -
pubmed
METHODS : In this open - label , partially controlled , 1 - year ( 14 [ 2 ] months ) extension study , data were collected from
patients with
IBS who continued treatment following a 2 - week study of the efficacy of the probiotic - prebiotic complex . -
pubmed
Curcumin attenuates
diabetic encephalopathy in
rats : behavioral and biochemical evidences . -
pubmed
on cognitive functions , oxidative stress and
inflammation in
diabetic rats . -
pubmed
There was 107 % and 121 % rise in
thiobarbituric acid reactive substance levels in cerebral cortex and hippocampus of
diabetic rats , respectively . -
pubmed
significantly attenuated
cognitive deficit ,
cholinergic dysfunction , oxidative stress and
inflammation in
diabetic rats . -
pubmed
The results emphasize the involvement of
cholinergic dysfunction , oxidative stress and
inflammation in the development of
cognitive impairment in
diabetic animals and point towards the potential of
curcumin as an adjuvant therapy to conventional anti -
hyperglycemic regimens for the prevention and treatment of
diabetic encephalopathy . -
pubmed
Twenty - nine
patients with
tuberculosis at the University Hospital in Vitoria , Brazil , participated . -
pubmed
Participants included forty
women , stratified into
obese versus non - obese groups based upon their baseline
body mass index , who had specimens corresponding to the three menopause stages . -
pubmed
METHOD : Visuoperceptual , language , memory and frontal lobe functions were evaluated in 30
participants with severe motor impaired
CP and a variety of speech difficulties . -
pubmed
Laryngeal and hypopharyngeal obstruction in
sleep disordered breathing
patients , evaluated by sleep endoscopy . -
pubmed
Despite the high response rates of
small cell lung cancer (
SCLC ) to first - line
cisplatin - based chemotherapies , most
patients with
SCLC will eventually experience
disease progression . -
pubmed
Newly developed
multiple myeloma in a
patient with
primary T - cell lymphoma of bone . -
pubmed
A 48 - yr - old
man was diagnosed as
T - cell PLB , stage IE , 18 months ago . -
pubmed
The
patient received the chemoradiotherapy and salvage chemotherapy for
PLB . -
pubmed
On bone marrow biopsy , the
patient was diagnosed as having
multiple myeloma newly developed with
primary T - cell lymphoma of bone . -
pubmed
In spite of chemotherapy , the
patient died of
renal failure . -
pubmed
Patients in the WHI group experienced a significant reduction in
pain score at 6 h ( P = 0.006 ) , 1 day ( P = 0.010 ) and 3 days ( P & lt ; 0.001 ) after operation , and in
morphine usage on day 2 ( P = 0.040 ) . -
pubmed
This prospective study aims at identifying the risk factors associated with
infections , obstructions and surgical complications of these devices in pediatric
patients . -
pubmed
METHODS : From January 2006 to January 2008 , all
children older than one year of age with a diagnosis of
solid or blood cell malignancy were included in the study . -
pubmed
Gentle cleansing and moisturizing for
patients with
atopic dermatitis and sensitive skin . -
pubmed
Respiratory infections caused by nontypeable
Haemophilus influenzae (
NTHi ) are a major medical problem . -
pubmed
One resembled the European ( Eu ) type of
potato tuber necrosis strain ( Eu - PVY ( NTN ) ) , possessing three widely recognized recombinant joints ( RJs 1 - 3 ) of the common
strain (
PVY(O ) ) and the
Eu - type tobacco veinal necrosis strain ( Eu - PVY(N ) ) . -
pubmed
Crofelemer , a purified
proanthocyanidin oligomer extracted from the bark latex of
Croton lechleri , is in clinical trials for
secretory diarrheas of various etiologies . -
pubmed
Paradoxically , low
body weight in middle aged and elderly
humans is associated with increased mortality . -
pubmed
Medulloblastoma in childhood : revisiting intrathecal therapy in
infants and
children . -
pubmed
INTRODUCTION : Intrathecal chemotherapy is being explored in
medulloblastoma in pre - school
children as part of brain - sparing strategies and as an alternative to unacceptably
neurotoxic cranio - spinal radiotherapy . -
pubmed
Retinol - induced intestinal
tumorigenesis in Min/+
mice and importance of
vitamin D status . -
pubmed
The effects of life - long dietary exposure , starting in utero , to high
retinol , low
vitamin D , or high
retinol in combination with low
vitamin D on intestinal
tumorigenesis in Min/+
mice were investigated . -
pubmed
In
males , high
retinol alone significantly increased the number ( 2.6 - fold ) and size ( 1.3 - fold ) of small intestinal
tumours ; in females no significant increase in
tumour number or size was seen . -
pubmed
In
females , however , the high
retinol / low
vitamin D - induced
increase in tumour number ( 3.1 - fold ) and
tumour size ( 1.5 - fold ) exceeded that of high
retinol alone . -
pubmed
METHOD :
Patients who developed
osteonecrosis as a complication of
ALL therapy between 1994 and 2007 were treated at a single paediatric institution . -
pubmed
All
patients demonstrated reduction in the radiological burden of
osteonecrosis with time . -
pubmed
CONCLUSION :
Bisphosphonate use , in particular
pamidronate , improved
pain scores , analgesic requirement and musculoskeletal function in
patients with
osteonecrosis occurring as a complication of childhood
ALL therapy . -
pubmed
In this study we highlight the high prevalence and relatively low control rate of misdiagnosed
IP ( pathology undetermined pre - operatively ) and hope to remind clinicians that early recognition of the
tumour is most beneficial to
patients . -
pubmed
CASE PRESENTATION : A 46 - year - old
woman was hospitalized with a preoperative diagnosis of
gallbladder carcinoma , The
patient was referred for surgical opinion and laparotomy was subsequently performed . -
pubmed
Transurethral endoscopic treatment of
patients with
upper tract urothelial carcinomas using
neodymium - YAG and/or
holmium - YAG laser ablation . -
pubmed
OBJECTIVE : To report our experience of treating
patients with original and recurrent
upper tract urothelial carcinomas (
UC ) using endoscopic lasers , with
holmium - YAG and/or
neodymium - YAG laser ablation , and for whom
tumour stage and grade were obtained by endoscopic biopsy . -
pubmed
PATIENTS AND METHODS : From March 2003 to March 2007 , 15
patients with
upper tract UC were treated with endoscopic laser ablation as the primary management . -
pubmed
RESULTS : Of the 15
patients , five had an upper tract
recurrence during the follow - up . -
pubmed
Three
patients had residual
tumours ; they were treated with repeated endoscopic laser treatments and had no
recurrence over a median ( range ) of 24 ( 13 - 26 ) months . -
pubmed
PATIENT(S ): One hundred nineteen
women with
infertility and 99 healthy female controls without
infertility between the ages of 18 and 45 years were included in this study . -
pubmed
To see whether this longevity is associated with
orthopaedic disability , especially physeal growth defects , we examined 105
patients aged between 5 - 25 years for evidence of clinically detectable
premature epiphyseal fusions (
PEF ) . -
pubmed
We aimed to examine the impact of
dysglycemia on outcomes in 173
recipients of HCT treated with glucocorticoids for
aGVHD . -
pubmed
These data suggest an independent adverse effect of
dysglycemia in
patients treated with glucocorticoids for
aGVHD , and argue for stringent glycemic control in this setting . -
pubmed
We have recently shown that the
cholesterol oxidation metabolite
27 - hydroxycholesterol (
27 - OHC ) causes
AD - like pathology in
human neuroblastoma SH - SY5Y cells and in organotypic hippocampal slices . -
pubmed
The rapidly - changing pattern of gonococcal antimicrobial susceptibility warrants the need for an antimicrobial susceptibility - monitoring programme , and periodical analysis and dissemination of susceptibility data are essential to guide clinicians and for successful
STI /
HIV intervention programmes . -
pubmed
We compared the frequency of myelosuppressive chemotherapy treatment , erythropoiesis - stimulating agent administrations , and red blood cell transfusions before and after the National Coverage Decision in oncology
patients with chemotherapy - induced
anemia . -
pubmed
RESULTS : A 32 - year - old
man presented with a typical image of
neuroretinitis ,
retinal hemorrhages and
sheathing of the retinal veins in the nasal retina . -
pubmed
Between 2005 and 2010 , 362
patients underwent elective lung resection for malignant or benign
lung tumors . -
pubmed
Of the seven
patients , six had primary
lung cancer (
PLC ) , and one had metastatic
cancer of the lung . -
pubmed
PQ was administered to Balb / c
mice as intraperitoneal doses of 0.01 , 0.1 , or 1.0 mg PQ / kg
body weight ( BW ) for a total of 28 days . -
pubmed
During a high speed road traffic accident , a 26 - year - old
man suffered multiple
fractures of his thoracic vertebrae and bilateral
pneumothoraces . -
pubmed
A 62 - year - old female
patient with a chief complaint of
back pain and continuous
fever was referred to our hospital . -
pubmed
Combination chemotherapy consisting of
gemcitabine and
doxorubicin is a treatment option for
patients with
spindle cell renal cell carcinoma . -
pubmed
BACKGROUND : Indonesia is one of the countries most severely affected by H5N1 highly pathogenic
avian influenza (
HPAI ) virus in terms of poultry and
human health . -
pubmed
In this study ,
H5N1 virus infection occurring in 96 smallholder duck farms in central Java , Indonesia from 2007 - 2008 was investigated and the molecular and antigenic characteristics of
H5N1 viruses isolated from these farms were analysed . -
pubmed
The high proportion of live duck cases compared to
chickens over the study period suggests that ducks are more likely to survive
infection and they may better suit the role of long - term maintenance host for H5N1 . -
pubmed
Clinical characteristics in 53
patients with
cat scratch optic neuropathy . -
pubmed
OBJECTIVE : To describe the clinical manifestations and to identify risk factors associated with visual outcome in a large cohort of
patients with
cat scratch optic neuropathy (
CSON ) . -
pubmed
Only 5
patients had significant
visual complications ( branch
retinal artery occlusion ,
macular hole , and
corneal decompensation ) . -
pubmed
CONCLUSIONS :
Patients with
CSON have a good overall visual prognosis . -
pubmed
Relative to time of diagnosis , the preclinical
AD persons deviated from the normal aging curve earlier ( up to 9 years ) compared to the preclinical
VaD persons ( up to 6 years ) . -
pubmed
Developmentally altered inhibition in Ts65Dn , a
mouse model of
Down syndrome . -
pubmed
Different from other types of
strabismus ,
children with
intermittent exotropia can maintain normal eye alignment and binocular vision in a long period of time . -
pubmed
Prior research suggests that
HCQ may reduce the risk of
diabetes mellitus in
patients with
RA . -
pubmed
A diet low in
animal fat and rich in
N - hexacosanol and
fisetin is effective in reducing symptoms of
Parkinson ' s disease . -
pubmed
METHODS : Forty - five
patients with
AOSD ( active = 22 , inactive = 23 ) and 32 healthy controls were included . -
pubmed
Twenty - four
patients with
AOSD and 18 controls were examined for cytotoxic activity of NK cells by co - incubating NK cells with
NK - sensitive K562 cells . -
pubmed
RESULTS : The proportions of NK cells were significantly lower in
patients with active
AOSD than in
patients with inactive disease and controls . -
pubmed
NK cell cytotoxic function was significantly lower in
patients with
AOSD than in controls . -
pubmed
NK cell proportions and
cytotoxic functions were reexamined in 11 and 6
patients , respectively , after treatment . -
pubmed
Low NK cell proportion and
cytotoxic dysfunction were improved with clinical improvements of the
patients . -
pubmed
BACKGROUND :
Arsenic Trioxide (
ATO ) is effective in about 20 % of
patients with
myelodysplasia (
MDS ) ; its mechanisms of action have already been evaluated in vitro , but the in vivo activity is still not fully understood . -
pubmed
For this analysis , we selected 12
patients affected by
MDS who received
ATO in combination with
Ascorbic Acid in the context of the Italian clinical trial NCT00803530 , EudracT Number 2005 - 001321 - 28 . -
pubmed
Two
patients achieved a major response : in the
patient with refractory
anemia the treatment down - regulated 69 % of the pro - apoptotic genes , whereas 91 % of the pro - apoptotic genes were up - regulated in the
patient affected by refractory
anemia with excess of blasts-1 . -
pubmed
We assessed the perspectives of community - dwelling
individuals with
chronic stroke on their hand function limitations and recovery to explore the feasibility of developing a theoretical framework for understanding the process of continued
post - stroke recovery . -
pubmed
METHODS : Eight
subjects with chronic
post - stroke hemiparesis were interviewed and videotaped while they performed a battery of 20 upper limb tasks . -
pubmed
CONCLUSIONS : These themes suggest a therapeutic framework for continued upper limb rehabilitation in
patients ' own environment to maximize functional recovery in individuals long after their
stroke , and generate hypotheses which may lead to the development of new therapeutic protocols . -
pubmed
Risk for
nephropathy is highest in
dogs homozygous for the mutations ( OR = 9.06 ; 95 % CI = 4.24 - 19.35 ) . -
pubmed
This is the first molecular characterization of an
inherited podocytopathy in
dogs and may serve as a model for continued studies of complex genetic and environmental interactions in
glomerular disease . -
pubmed
Enzootic
pneumonia , resulting from
infection with
Mycoplasma hyopneumoniae , is of considerable economic importance to the
pig industry and normally is controlled through active vaccination of piglets . -
pubmed
We have demonstrated that administration of an inactivated
Mycoplasma hyopneumoniae vaccine to
piglets less than 1 week old is efficacious under field conditions and reduces the level of
lung lesions observed in comparison to that in control
pigs . -
pubmed
The number of
lung lesions was recorded 4 weeks after challenge , and bronchial swab and lung tissue specimens were analyzed for quantification of
Mycoplasma hyopneumoniae DNA . -
pubmed
PURPOSE : The aim was to compare preventive effect of total parenteral nutrition ( TPN ) and oral nutrition ( preOp ) on the perioperative
insulin resistance prevention in surgical
gastrointestinal cancer patients . -
pubmed
MATERIAL / METHODS : The study was conducted in a group of 75 elective
gastric and large intestine cancer patients . -
pubmed
However , a majority of
strains were isolated from rocky shores and , in particular ,
red seaweed surfaces and mollusks . -
pubmed
The 14
patients in the active microcurrent group [ mean , 10.8 ( 2.9 ) days ; range , 7 - 15 days ] experienced no difference in time to
wound healing as compared to the remaining
patients in the sham microcurrent group [ mean , 11.1 ( 2.0 ) days ; range , 8 - 14 days ; P = 0.75 ] . -
pubmed
CONCLUSIONS : In a sample size of 25
burn patients , the addition of direct microcurrent to
silver -
nylon dressings did not decrease time to wound closure of skin donor sites , and it did not show a difference in reported
pain levels . -
pubmed
Cardiovascular responses during a submaximal exercise test in
patients with
Parkinson ' s disease . -
pubmed
BACKGROUND :
Patients with
Parkinson ' s disease (
PD ) are physically less active than controls , and
autonomic dysfunction may contribute to this sedentary lifestyle . -
pubmed
OBJECTIVE : To assess the cardiovascular responses to a submaximal exercise test in
PD patients and controls , 546 sedentary
PD patients and 29 sedentary healthy controls performed the Astrand - Rhyming submaximal cycle exercise test . -
pubmed
Variables that may affect submaximal activity in
PD patients , including disease severity ,
fatigue , and level of physical activity in daily life , were recorded . -
pubmed
RESULTS : Fewer
PD patients ( 46 % ) completed the submaximal exercise test successfully than the controls ( 86 % ) . -
pubmed
PD patients with a successful submaximal exercise test had lower estimated VO2max values than controls . -
pubmed
Pre - clinical studies and recently reported
human trials suggest that pre - erythrocytic stage vaccines can provide protection against
infection . -
pubmed
PATIENTS AND METHODS : 80
women ( mean age 73 + - 5 years ) with early
breast cancer were retrospectively evaluated . -
pubmed
30 - 45 days after the percutaneous ablation , all
patients underwent surgical resection of the
tumor . -
pubmed
In 75
patients ( 93.8 % ) we observed complete
necrosis ; in 5 cases there was residual disease in the postprocedural MRI and postoperative histological examination . -
pubmed
Here we uncover roles for mitochondrial reactive
oxygen species ( mtROS ) during
Drosophila dorsal closure , a model for
wound healing . -
pubmed
RESULTS : Children with
cCMV ( n=34 ; 12
males , 22 females ; mean [ SD ] gestational age , 36.4 wk [ 4.4 ] , range 24 - 41 wk ) accounted for 1.5 % of
CP cases ; 2.9 per 100,000 live births , ( 95 % confidence intervals 1.9 - 3.9 ) . -
pubmed
The majority of the
patients are treated with the sphincter - sparing surgical procedure low anterior resection , and 50 % to 90 % of these patients experience
bowel dysfunction , known as the
low anterior resection syndrome . -
pubmed
PATIENTS : All
patients had undergone low anterior resection for
rectal cancer , had no stoma , had no dissemination or recurrence at the time of the study , and were at least 16 months past surgery . -
pubmed
In comparison with patients without low anterior resection
syndrome ,
patients with major low anterior resection
syndrome fared substantially worse in all selected subscales ( difference & gt;= 10 points , p & lt ; 0.01 ) , with the exception of
constipation . -
pubmed
The majority of studies contain a heterogeneous cohort of subjects , often combining
patients with and without
spondylolisthesis who received various surgical interventions , limiting fusions to those
patients with instability . -
pubmed
It is difficult if not impossible , therefore , to formulate valid conclusions regarding the utility of fusion for
patients with uncomplicated
stenosis . -
pubmed
The patient was a 47 - year - old
man with
deep - vein thrombosis . -
pubmed
The prevalence of EEG , PHES and CFFo / CFFm abnormalities was significantly higher in
patients with grade I overt
HE . -
pubmed
The prevalence of EEG abnormalities was significantly higher in
patients with a history of
HE . -
pubmed
This paper reports distinctive temporal - volatile profiles from three abiotic treatments , room temperature ( control ) , -15 C ( cold ) , and -15 C to room temperature (
shock ) , of
cactus tissue plugs . -
pubmed
Plasma total
25 ( OH ) D ,
25 ( OH ) D2 , and
25 ( OH ) D3 levels were measured by liquid chromatography - tandem mass spectrometry in
PD patients ( n = 478 ) and controls ( n = 431 ) . -
pubmed
The current study , however , can not exclude the possibility that
gastrointestinal dysfunction , a
non - motor PD symptom , contributes to the lower
vitamin D2 levels in
PD patients . -
pubmed
The study also revealed a high prevalence of
infection in
P. - pubmed
We report the outcomes of a series of
patients with pelvic
recurrences from
colorectal cancer reirradiated with SBRT . -
pubmed
Early diagnosis can result in prompt management of the patient since
wrist pain in older
individuals due to aging may go unnoticed or be due to other diagnoses with the production of greater damage and eventually a worse prognosis . -
pubmed
Given that older and stronger memories are generally more resistant to change , we tested whether disrupting reconsolidation would also diminish fear in
individuals who had developed a persistent
spider fear outside the laboratory . -
pubmed
Depression in
patients with
alcohol use disorders : Systematic review and meta - analysis of outcomes for independent and substance - induced disorders . -
pubmed
BACKGROUND : In
patients with an
alcohol use disorder ,
depression is commonly categorised as independent ( ID ) or substance - induced (
SID ) . -
pubmed
The effect of antidepressant therapy on
depression in
patients with
alcohol use disorders is modest , with stronger evidence in ID . -
pubmed
Postmenopausal
women experienced
pain during SCSH more often than premenopausal
women did : 71 % ( 17/24 ) compared with 32 % ( 24/75 ) experienced
pain ; p & lt ; 0.002 ; the median tolerance on the 100 - mm visual analog scale was 43 . -
pubmed
MATERIALS AND METHODS : A retrospective chart review study was conducted at Department of Clinical Chemistry , King Abdulaziz Medical City ( KAMC ) in Riyadh , Saudi Arabia , during the period from August 2014 to December 2014 , including 100 male and female
patients diagnosed with
diabetes mellitus (
DM ) type 2 and excluding
patients with
DM type 1 . -
pubmed
In the third simulated trial , risk of
MACE was significantly greater in
patients switching from
rosuvastatin to
atorvastatin than in those remaining on
rosuvastatin ( RR at 5 years : 1.109 ; P<0.001 ) . -
pubmed
Proteomic profiling of epileptogenesis in a
rat model : Focus on
inflammation . -
pubmed
The questionnaire included questions about
pain and sensory abnormalities located to the abdominal skin , and physical and psychological function ;
patient satisfaction with surgery was rated on a 4 - point scale . -
pubmed
MATERIALS AND METHODS :
Chronic kidney disease was created in
C57BL / 6 mice ; 28 days later , an AVF was created by connecting the right carotid artery to the ipsilateral jugular vein . -
pubmed
METHODS : In a sample of 70 twins discordant for
schizophrenia and 130 healthy control twins , structural equation modeling was applied to quantify unique contributions of genetic and environmental factors on
human brain structure ( cortical thickness , cortical surface and global white matter fractional anisotropy [ FA ] ) , intellectual ability and
schizophrenia liability . -
pubmed
METHODS : Here , 107
patients with biopsy - proven locally advanced
NPC between March 2004 and January 2011 were enrolled in the retrospective study . -
pubmed
The activity of enzymes of glycolysis has been studied in erythrocytes from
type - II diabetic patients in comparison with control . -
pubmed
cerulea and
Quercus agrifolia Nee against a DeltatolC mutant
strain of
Escherichia coli . -
pubmed
Poster 321
Trazodone Associated
Clitoral Priapism in a Transgender
Man following
Traumatic Brain Injury : A Case Report . -
pubmed
Actinomycosis is a chronic suppurative
granulomatous infection of subcutaneous tissues caused by bacterium
Actinomyces israelii . -
pubmed
Infection is first established locally by breach of mucosal barrier during various procedures , aspiration ,
trauma , or
human bite . -
pubmed
In this study , we enhance the radiosensitivity of
HCT116 human colorectal cells with
tiopronin - coated GNPs ( Tio - GNPs ) combined with a low - energy X - ray ( 26 keV effective energy ) source , similar to the Papillon 50 clinical irradiator used for topical irradiation of rectal
tumors . -
pubmed
In
nude mice bearing the
HCT116 tumor , intra - tumoral ( IT ) injection of Tio - GNPs allowed a 94 times higher quantity of Tio - GNPs to accumulate than was possible by intravenous injection and facilitated a significant
tumor response . -
pubmed
It includes the topics 1 )
gambling disorder from the neuroimaging and electroencephalography ( EEG ) perspective , 2 ) cognitive , executive functioning , and neuropsychological aspects of
gambling disorder , and 3 )
rodent models of
gambling disorder . -
pubmed
INTRODUCTION : The aim is to analyze the functional outcomes of
patients of
giant cell tumor (
GCT ) of distal radius treated with ulnar translocation and wrist arthrodesis . -
pubmed
METHODS : Study included 25
patients of aggressive
GCT of distal radius , resected and reconstructed using ulnar translocation and wrist arthrodesis . -
pubmed
The aim of this study was to evaluate the authors ' experience of sialendoscopy of the salivary glands in
patients with
SS . -
pubmed
MATERIALS AND METHODS : In this retrospective case series study , the surgical data of
patients with
SS who had undergone sialendoscopy at the VU University Medical Center ( Amsterdam , The Netherlands ) from November 2014 through April 2015 were used . -
pubmed
RESULTS : Surgical data of sialoendoscopic procedures in 26
patients with
SS ( 24
women and 2
men ; mean age , 57 yr ; range , 27 to 72 yr ) were analyzed . -
pubmed
Three
patients developed a
postoperative infection . -
pubmed
CONCLUSION : The overall rate of complications was limited and the sialoendoscopic complications in
patients with
SS could be regarded as minor . -
pubmed
Design and rationale for the WARFA trial : a randomized controlled cross - over trial testing the therapeutic equivalence of branded and generic
warfarin in
atrial fibrillation patients in Brazil . -
pubmed
METHODS : Prospective cohort of consecutive
patients with
ASBO . -
pubmed
MAIN OUTCOME : Intestinal
necrosis (
IN ) in 10
patients ( 21.3 % ) . -
pubmed
CONCLUSIONS : PCT levels are closely related to the presence of intestinal
ischemia and
necrosis in
children with ASBO . -
pubmed
The Combined Intervention with Germinated
Vigna radiata and Aerobic Interval Training Protocol Is an Effective Strategy for the Treatment of
Non - Alcoholic Fatty Liver Disease (
NAFLD ) and Other Alterations Related to the
Metabolic Syndrome in Zucker
Rats . -
pubmed
In the present experiment , the combined treatment with
mung bean (
Vigna radiata ) , a widely used
legume with promising nutritional and health benefits that was included in the experimental diet as raw or 4 day - germinated seed flour , and aerobic interval training protocol ( 65 - 85 % VO2 max ) has been tested in lean and
obese Zucker
rats following a 2 x 2 x 2 ( 2 phenotypes , 2 dietary interventions , 2 lifestyles ) factorial ANOVA ( Analysis of Variance ) statistical analysis . -
pubmed
radiata at improving the aerobic capacity and physical performance , hepatic histology and functionality , and plasma lipid parameters as well as reverting the
insulin resistance characteristic of the
obese Zucker
rat model . -
pubmed
In conclusion , the joint intervention with
legume sprouts and aerobic interval training protocol is an efficient treatment to improve the alterations of
glucose and lipid metabolism as well as hepatic histology and functionality related to the development of
NAFLD and the
MetS. -
pubmed
Numerous studies have demonstrated the suitability of
zebrafish (
Danio rerio ) embryos as a model to in vivo studies of
Pseudomonas aeruginosa infection . -
pubmed
In most
zebrafish - pathogen studies ,
infection is achieved by microinjection of bacteria into the larvae . -
pubmed
METHODS : We performed intravascular ultrasound ( IVUS ) with virtual histology in 98
patients prior to elective bare - metal stent ( BMS ) implantation in de novo
coronary artery lesions . -
pubmed
Subgroup analysis after exclusion of
acute coronary syndrome (
ACS )
patients yielded similar results . -
pubmed
SUBJECTS AND METHODS : One hundred and fifty
patients with
epilepsy were recruited between May 2016 and August 2016 . -
pubmed
For assessing
depression , Tamil validated version of
Patient Health Questionnaire-12 was used . -
pubmed
Depressive symptoms were present in 95
patients ( 63.3 % ) . -
pubmed
First time non -
cardiogenic ischemic stroke patients were enrolled and screened within 30 days . -
pubmed
Participants were randomized to receive either
triflusal or
clopidogrel for secondary
stroke prevention . -
pubmed
According to Paprosky classification , 2
patients had type IIB defect , 4 had
type IIC , and 12 had type IIIA , while 8 suffered from
type IIIB defect . -
pubmed
Early
brain injury (
EBI ) is the primary cause of poor outcome in
subarachnoid hemorrhage (
SAH )
patients . -
pubmed
Adult male
Sprague - Dawley rats were subjected to an endovascular perforation process to produce an
SAH model . -
pubmed
Edoxaban for the Treatment of
Venous Thromboembolism in
Patients with
Cancer . -
pubmed
Congenital anomalies of the kidney and urinary tract (
CAKUT ) are among the most common
developmental defects in
humans . -
pubmed
Methods : We compared the prognostic value of traditional demographic and cytogenetic risk factors , genomic data in the form of somatic aberrations of 25
AML - relevant genes , and whole - transcriptome expression profiling ( RNA sequencing ) in 267 intensively treated
AML patients ( Clinseq -
AML ) . -
pubmed
METHODS : A total of 28
patients ( n = 14 , 46,XX ; n = 14 , 46,XY ) with classical
11BOHD from 25 unrelated families were included in this study . -
pubmed
Two male
patients had
testicular microlithiasis and 5 ( 35.7 % ) patients had
testicular adrenal rest tumor during follow up . -
pubmed
Four
patients ( 28.6 % ) had
gynecomastia . -
pubmed
METHODS : From forty 4 - 5 months old SD
rats , 30 were randomly selected for the establishment of the model of testicular UU
infection by inoculating the bladder with UU suspension and the other 10 injected with normal saline as controls ( group A ) . -
pubmed
At 7 days after inoculation , the
rat models of
testicular UU infection were treated orally with normal saline ( group B ) , ZDD at 1 g per kg of the
body weight per day ( group C ) , and
azithromycin at 0.105 g per kg of the
body weight per day ( group D ) , respectively , once daily for 21 days . -
pubmed
Objective : To determine if
patients with
OSA have
thinner skulls than
patients without
OSA . -
pubmed
Patients with moderate to severe
OSA (
apnea - hypopnea index [ AHI]>=25 / h ) and without
OSA ( AHI<5 / h ) were matched for age and
body mass index (
BMI , calculated as weight in kilograms divided by height in meters squared ) . -
pubmed
Patients with
OSA had thinner mean ( SD ) calvaria ( 2.73 [ 0.67 ] vs 2.47 [ 0.52 ] mm ; difference , -0.26 mm ; 95 % CI , -0.49 to -0.04 ; Cohen d , 0.44 ) and thinner skull bases ( 5.03 [ 1.40 ] vs 4.32 [ 1.28 ] mm ; difference , -0.71 ; 95 % CI , -1.23 to -0.19 ; Cohen d , 0.53 ) . -
pubmed
The
tegmen mastoideum was dehiscent in nearly twice as many
patients with
OSA as those without ( 37 % vs 20 % ; difference , 17 % ; 95 % CI , 0.4 - 32 ) . -
pubmed
METHODS : Three radio - resistant
human rectal cancer cell lines (
SNU-61R80Gy ,
SNU-283R80Gy , and
SNU-503R80Gy ) were established from
human rectal cancer cell lines (
SNU-61 ,
SNU-283 , and
SNU-503 ) using total 80 Gy of fractionated irradiation . -
pubmed
Microarray analysis was performed to identify differently expressed genes in newly established radio - resistant
human rectal cancer cells compared to parental
rectal cancer cells . -
pubmed
To evaluate whether the
alpha , beta - unsaturated carbonyl can be used for
intracerebral hemorrhage (
ICH ) therapy , we investigated the effect of
shogaol on an in vivo
mouse ICH model . -
pubmed
Transpulmonary pressure , that is the difference between airway pressure ( Paw ) and pleural pressure , is considered one of the most important parameters to know in order to set a safe mechanical ventilation in
acute respiratory distress syndrome (
ARDS ) patients but also in
critically ill obese
patients , in
abdominal pathologies or in pathologies affecting the chest wall itself . -
pubmed
Esophageal pressure ( Pes ) is considered the best surrogate of pleural pressure in
critically ill patients , but concerns about its reliability exist . -
pubmed
Protein - rich extract of
Musca domestica larvae alleviated
metabolic disorder in
STZ - induced
type 2 diabetic rat model via hepatoprotective and pancreatic beta - cell protective activities . -
pubmed
The study was designed to explore the beneficial effect of
Musca domestica larvae extract ( MDLE ) on a
metabolic disorder using a
diabetic rat model . -
pubmed
Streptozotocin - induced
diabetic rats were treated with or without MDLE . -
pubmed
Tanoak (
Lithocarpus densiflorus ) is a principal host of
Phytophthora ramorum , cause of
sudden oak death (
SOD ) , in the western United States ( 1 ) . -
pubmed
A lung -
tumor patient was simulated with differently shaped
tumor - mimicking inlays in a thorax - phantom . -
pubmed
[ Possibilities and advantages of minimally invasive dorsal decompressive - stabilizing interventions in the treatment of
degenerative spondylolisthesis of the elderly
patients . ] -
pubmed
The purpose of the study was a comparative analysis of the clinical and radiographic efficacy of minimally invasive rigid stabilization techniques and the traditional open interbody fusion with transpedicular fixation in the treatment of
degenerative spondylolisthesis in elderly
patients . -
pubmed
Low traumatic surgery in the main study group makes it possible to use a technique for treating
degenerative spondylolisthesis in elderly
patients . -
pubmed
METHODS : From January 2016 through March 2018 , consecutive
children with
CLD without a history of
variceal bleeding were prospectively included . -
pubmed
Esophagogastroduodenoscopy was done in all the
children to detect and to grade
esophageal varices . -
pubmed
RESULTS : Of 288
patients with
RA , 204 ( 70.8 % ) and 84 ( 29.2 % ) continued standard dose treatment and underwent down - titration treatment , respectively . -
pubmed
METHODS : For this feasibility study , we enrolled 27 adult
patients presenting to the day hospital with
acute pain . -
pubmed
As expected , we found that
pain scores and heart rate decreased for most
patients during the course of their stay . -
pubmed
Safety and Efficacy Evaluation of Traditional Chinese Medicine ( Qingre - Lishi - Yishen Formula ) Based on Treatment of Regular Glucocorticoid Combined with
Cyclophosphamide Pulse in
Children Suffered from Moderately Severe
Henoch - Schonlein Purpura Nephritis with
Nephrotic Proteinuria . -
pubmed
Objective : At present , the most appropriate management of
Henoch - Schonlein purpura nephritis (
HSPN ) with
nephrotic - range
proteinuria still remains controversial ; thus , the purpose of this study is to evaluate safety and efficacy of traditional Chinese medicine ( TCM ) , Qingre - Lishi - Yishen Formula ( QLYF ) , integrated with regular oral
glucocorticoid and
cyclophosphamide intravenous
pulse therapeutic regimen in
children suffered from moderately severe
HSPN with
nephrotic proteinuria . -
pubmed
Methods : From 1 January 2012 , to 1 January 2016 , totally 150 hospitalized
children suffered from
HSPN with
nephrotic proteinuria were included . -
pubmed
Results : Total adverse event rate was lower in the QLYF group ( chi 2 = 5.357 , p = 0.022 ) ; rates of
respiratory infection ,
urinary infection ,
poor appetite ,
hepatotoxity ,
cardiotoxicity , and
neutropenia were all decreased in
patients who received QLYF ( p = 0.022 ) ; rates of
respiratory infection ,
urinary infection ,
poor appetite ,
hepatotoxity ,
cardiotoxicity , and
neutropenia were all decreased in
patients who received QLYF ( p = 0.022 ) ; rates of
respiratory infection ,
urinary infection ,
poor appetite ,
hepatotoxity ,
cardiotoxicity , and
neutropenia were all decreased in
patients who received QLYF ( p = 0.022 ) ; rates of
respiratory infection ,
urinary infection ,
poor appetite ,
hepatotoxity ,
cardiotoxicity , and
neutropenia were all decreased in
patients who received QLYF ( p = 0.022 ) ; rates of
respiratory infection ,
urinary infection ,
poor appetite ,
hepatotoxity ,
cardiotoxicity , and
neutropenia were all decreased in
patients who received QLYF ( p = 0.022 ) ; rates of
respiratory infection ,
urinary infection ,
poor appetite ,
hepatotoxity ,
cardiotoxicity , and
neutropenia were all decreased in
patients who received QLYF ( . -
pubmed
Conclusion : Compared with merely using regular oral
glucocorticoid plus
cyclophosphamide pulse therapeutic regimen , the therapeutic regimen that integrates QLYF with the abovementioned western medicine might be a safe means to decrease the occurrence rate of adverse events and improve short - term and long - term clinical effects in
children who suffered from moderately severe
HSPN with
nephrotic proteinuria . -
pubmed
Favipiravir cures all
mice in a lethal
influenza infection model , while
oseltamivir fails to cure the animals . -
pubmed
In addition to
influenza ,
favipiravir has a broad spectrum of anti - RNA virus activities in vitro and efficacies in animal models with lethal RNA viruses and has been used for treatment of
human infection with life - threatening
Ebola virus ,
Lassa virus ,
rabies , and severe
fever with
thrombocytopenia syndrome . -
pubmed
The primary endpoint was the development of
sepsis between 2011 and 2015 , and the secondary endpoint was 30 - day mortality among
diabetes patients diagnosed with
sepsis . -
pubmed
CONCLUSIONS : Prior
metformin therapy was not significantly associated with the risk of
sepsis and 30 - day mortality after diagnosis of
sepsis among
diabetes patients . -
pubmed
AEN can arise in
critically ill patients with multiple comorbidities and is an uncommon complication of
diabetic ketoacidosis (
DKA ) . -
pubmed
We present a case of a young
female with poorly controlled ,
insulin - dependent diabetes mellitus type 2 who developed
odynophagia , small volume coffee - ground
emesis , and inability to tolerate oral intake after resolution of
DKA . -
pubmed
Thus ,
AEN should be considered in the differential diagnosis for
critically ill patients who present with vague symptoms such as
odynophagia and
gastrointestinal bleeding . -
pubmed
In
fingolimod - treated
patients only , female sex and a higher Expanded Disability Status Scale score were predictors of
lymphopenia at 12 months ( p = 0.006 , odds ratio = 7.58 and p = 0.03 , odds ratio = 1.56 ) . -
pubmed
CONCLUSIONS : Our findings suggest that peripheral blood lymphocyte changes are not associated with short - term treatment response and with the rate of
infections during
fingolimod and
dimethyl - fumarate treatment in real - world
patients . -
pubmed
METHODS : This study included 110
BPH patients treated in our hospital from August 2017 to April 2018 , who were randomly assigned to receive HoLEP ( n = 55 ) or HoLEP + JSSD ( n = 55 ) . -
pubmed
CONCLUSIONS : HoLEP + JSSD can significantly alleviate the
lower urinary tract symptoms as well as improve the QOL and bladder and urinary tract functions of
BPH patients . -
pubmed
Patients with
acute myocardial infarction experienced a higher number of
hypoglycemic events compared with unstable
angina diagnosed
patients . -
pubmed
In our previous study ,
Hydrostatin - SN1 , a bioactive peptide extracted from the
Hydrophis cyanocinctus venom gland T7 phage display library , demonstrated anti - inflammatory activity in a dextran sulfate
sodium - induced
murine colitis model . -
pubmed
In LPS - induced acute
shock model , a significant higher survival rate of Hydrostatin - SN1 - treated
mice was observed . -
pubmed
CASE PRESENTATION : We report the case of a 65 - year - old
male with a
PPMM who has prolonged survival of more than 104 weeks after combined microsurgical and endoscopic total resection . -
pubmed
BACKGROUND :
Hypokalemia and
hypomagnesemia caused due to renal losses with
chloride - resistant
metabolic alkalosis in normotensive
patients should remind clinicians of the rare
inherited tubulopathy ,
Gitelman syndrome . -
pubmed
CONCLUSION : This lifelong disease could cause life - threatening conditions due to the cardiac complications of
hypokalemia in some of the affected
patients . -
pubmed
Therefore , it is necessary to be aware of the appropriate diagnosis and treatment for
patients admitted to the clinic with
hypokalemia ,
hypomagnesemia ,
hypocalciuria , and
hyperreninemia . -
pubmed
A weight of evidence assessment of the genotoxic potential of
4 - methylimidazole as a possible mode of action for the formation of
lung tumors in exposed
mice . -
pubmed
Two - year
rodent bioassays via oral exposure conducted by the National Toxicology Program reported evidence of
carcinogenicity only in
B6C3F1 mice ( increased
alveolar / bronchial neoplasms ) . -
pubmed
In 2011 , the International Agency for Research on
Cancer classified
4 - MeI as Group 2B , " possibly carcinogenic to
humans " . -
pubmed
An expert panel was commissioned to assess the genotoxic potential of
4 - MeI and the plausibility of a genotoxic mode of action in the formation of
lung tumors in
mice when exposed to high doses of
4 - MeI. -
pubmed
Based on the reviewed studies ' weighted contribution , the panel unanimously concluded that the WOE supports no clear evidence of in vivo
genotoxicity of
4 - MeI and no association for a genotoxic mode of action in the formation of
mouse lung tumors . -
pubmed
AF was associated with early discontinuation of
trastuzumab in
patients with
breast cancer . -
pubmed
Tumor sizes of
patients in the TACE -
apatinib group were more frequently classified as small ( < 5 cm ) compared to those in the TACE alone group ( P = 0.021 ; mean : 8.6 cm vs. 10.2 cm ) . -
pubmed
Conclusions : TACE combined with
apatinib may result in superior OS compared to TACE therapy alone for
HCC patients with macrovascular invasion . -
pubmed
METHODS :
Infants with
congenital heart disease were randomly divided into the breast milk oral stimulation group ( n = 23 ) , physiological saline oral stimulation group ( n = 23 ) and control group ( n = 23 ) . -
pubmed
Visual word form processing deficits driven by severity of
reading impairments in
children with
developmental dyslexia . -
pubmed
Here , we report fMRI data from a multicentre study with 140
children in primary school ( 7.9 - 12.2 years ; 55
children with
dyslexia , 73 typical readers , 12 intermediate readers ) . -
pubmed
BACKGROUND : One of the most feared complications of rhytidectomy is the formation of
hematoma and
seroma , which may harm
patients ' health and compromise the surgical outcome . -
pubmed
Time - course comparison of
pulmonary inflammation induced by intratracheal instillation of four different
nickel oxide nanoparticles in male
Fischer rats . -
pubmed
The NiOs were suspended in purified water and instilled once intratracheally into male
F344 rats ( 12 weeks old ) at 0 ( vehicle control ) , 0.67 , 2 , and 6 mg / kg
body weight . -
pubmed
To develop intravital criteria of the reperative processes following
myocardial infarction , clinical , biochemical and morphological parallels were traced in 62
patients dying of
myocardial infarction after different periods following the onset of the disease . -
pubmed
A second component of
Australian tiger snake venom was also found to be
myotoxic . -
pubmed
Notexin could be neutralized by incubation with
tiger snake antivenene ; the simultaneous injection of
antivenene with notexin did not afford complete protection against
muscle damage . -
pubmed
Indoprofen , a new non - steroidal anti - inflammatory drug , in the treatment of
osteoarthrosis : report on a multi - centre study in 1629
patients . -
pubmed
A multi - centre trial was carried out in 1629
patients with
osteoarthrosis in 233 clinical centres to investigate the therapeutic efficacy and tolerability of
indoprofen in this clinical condition . -
pubmed
The results indicate that sera from a large proportion of
patients with
adenocarcinomas of the digestive tract , pancreas , and breast are capable of inhibiting the above inactivation , whereas most normal sera do not inhibit . -
pubmed
This phenomenon may be implicated in the pathogenesis of
human breast cancer . -
pubmed
Clinical course , early and late complications as well as treatment of
ophthalmic zoster in 70 hospitalized
patients are presented . -
pubmed
This work investigated the pattern of ACTH and
cortisol response to
hypoglycemia in
goats and the effect of
dexamethasone on this response . -
pubmed
It is suggested that there is no value in the routine performance of liver function tests in
patients with
epilepsy . -
pubmed
Stress proteins and cross - protection by heat
shock and salt stress in
Bacillus subtilis . -
pubmed
We report here genetic recombination between 2 USDA - licensed vaccine
strains of
pseudorabies virus co - inoculated into
swine . -
pubmed
Co - inoculation resulted in the creation of novel
strains of
pseudorabies virus containing negative immunologic markers with restored virulence genes . -
pubmed
Plaque - purified recombinant progeny viruses were found in 2 litters of
pigs in which both
strains were co - inoculated IM , a litter in which both
strains were co - inoculated oronasally , and a litter in which the conventionally attenuated
strain was inoculated oronasally and the genetically engineered
strain was inoculated IM . -
pubmed
The creation , spread , and potential misdiagnosis of these types of recombinant
strains could disrupt control and eradication programs that are based on the serologic identification of
swine infected with potentially virulent
strains of
pseudorabies virus . -
pubmed
However , when injected in
patients with
LA , IVIg do not seem to operate by this mechanism of action . -
pubmed
Electric field stimulation of
human osteosarcoma - derived cells : a dose - response study . -
pubmed
In vitro electrical stimulation of
human osteosarcoma - derived cells resulted in increased cell adherence and current directed cell migration . -
pubmed
For the first time R - bodies are described in a new
strain 44T1 of
Pseudomonas aeruginosa . -
pubmed
The echocardiographic features and management of 10
children with
right heart thrombus (
RHT ) are presented . -
pubmed
The
thrombus was detected in the right atrium ( five
patients ) , in the right ventricle ( three ) , on the tricuspid valve or within the inferior vena cava , the superior vena cava , or its extension following Senning 's operation for transposition of great arteries (
TGA ) . -
pubmed
In two of three
patients with anatomically normal heart , the
thrombus occurred as a complication of a ventriculoatrial and a lymphovenous shunt system . -
pubmed
Transplantation of
Lewis lung carcinoma in
mouse uterus . -
pubmed
Earlier studies have shown that pregnant and nonpregnant
mammalian uteri respond differently to
tumor cell invasion , colonization and
metastasis , but the biological basis of such differential uterine response has not been clarified . -
pubmed
In the present study we have investigated the role of the metastatic potential of the
tumor in the differential response of different stages of
mouse uteri , using a highly metastatic
tumor . -
pubmed
In the
tumor cell - treated
animals , despite an early and uniform invasion the patterns of
tumor cell colonization and
metastasis differed remarkably from the pregnant to nonpregnant uteri . -
pubmed
Though 40 % of the pregnant
animals had
tumor cells in the uteri , none had
metastasis in other organs . -
pubmed
These results indicate the refractory nature of both the pregnant and nonpregnant
mouse uteri to the survival and colonization of LLC cells , but the mechanisms by which the
tumor cells are eliminated differ between these two types of uteri . -
pubmed
Chronic myeloid leukemia (
CML ) was diagnosed in a 19 - year - old
man in 1961 , and the disease remained in chronic phase , with occasional exacerbations , for 27 years . -
pubmed
Rearranged
Epstein - Barr virus genomes and clonal origin in
nasopharyngeal carcinoma . -
pubmed
Epstein - Barr virus (
EBV ) is known to be associated with two
malignant diseases ,
nasopharyngeal carcinoma (
NPC ) and endemic
Burkitt ' s lymphoma . -
pubmed
In this study , the genomes of
EBV in biopsy specimens from 4
NPC patients in Japan were analyzed using Southern blot hybridization . -
pubmed
The
animal model employed here might be suitable for studying the effects of
hypoxia in newborns and
children during chest operations involving the descending aorta . -
pubmed
Local administration was performed for
patients with
skin malignancy , and
bladder and hepatic carcinoma . -
pubmed
Among 239
cases eligible for evaluation ( 144 cases treated by systemic administration and 95 cases by local injection ) , complete response was observed in one case each of
renal cell carcinoma ,
malignant lymphoma and
mycosis fungoides , all treated by systemic administration . -
pubmed
Fever was observed in 89 % of the
cases treated by systemic administration . -
pubmed
Conditions for efficient regeneration in mutant
strains of the
doxorubicin - producing organism
Str . - pubmed
The lower control rate in
patients who had surgery alone could be due ( in part ) to inadequate surgery at the primary site ( 42 % local excision ) and lack of neck dissection ( 35 % for
SA vs. 77 % for S + R ) . -
pubmed
Postoperative radiation therapy to the primary site and neck is shown to effectively reduce local
recurrence in
patients with oral cavity and
oropharynx cancer , regardless of
surgical margins . -
pubmed
Ambulatory nursing of
patients with
infections ] . -
pubmed
[ Analgesia for dental interventions in
ischemic heart disease patients with intolerance to local anesthetic preparations ] . -
pubmed
Primary
zinc deficiency conditions of the magnitude seen in this study and in this - age
rat did not appear to alter serum
thyroid hormone levels or organ / glandular function . -
pubmed
For
patients with less frequent recurrent
HSV episodes involving localised and accessible sites topical
acyclovir cream may be preferred to the equally effective but more expensive oral
acyclovir . -
pubmed
The in vitro DNA - intercalator
ellipticine and five of its derivatives have been investigated for some of their physiological effects on several
Escherichia coli strains . -
pubmed
Sialic acid (
N - acetylneuraminic acid ) in the synovial fluid and serum of
patients with
inflammatory and non - inflammatory joint disease . -
pubmed
We reviewed our experience over the past six years with retroperitoneal inflow procedures ( aortofemoral and iliofemoral bypass grafts ) in high - risk
patients with
aortoiliac occlusive disease . -
pubmed
Twenty percent of the
patients were
diabetic , 80 % were smokers , 40 % had
heart disease , 54 % had
hypertension , and 25 % had symptomatic
chronic obstructive pulmonary disease . -
pubmed
The serum concentration of
salbutamol was determined in 29 pregnant
women during oral treatment ( 4 mg five times per day ) and in seven during intravenous infusion ( 6 - 30 micrograms / min ) because of
premature labour . -
pubmed
Deficiency of the fourth component of complement in
man . -
pubmed
Lymphographic findings in a series of 258
patients with
tumors of the testes . -
pubmed
[ Acute
basophil leukemia with cutaneous and osseous manifestations revealing
saturnism in young
children ] . -
pubmed
The rehabilitation of long - stay
schizophrenic patients . -
pubmed
[ The effect of vaporization with thermal sulfurous water on
phospholipids in the broncho - alveolar lavage solution following hypobaric
hypoxia in the
rat ] . -
pubmed
We have studied , in the
rat , the action of a vaporization with sulphurous water from Bagneres de Luchon on the surfactant modifications caused by
hypoxia . -
pubmed
So we can conclude that a vaporization with sulphurous water had a protective action against
hypoxia on the broncho - alveolar lavage of
rat lung . -
pubmed
[ Hormone - dependent enhancement of malignant phenotype in cells infected with
mouse mammary
tumor virus (
MMTV ) , and role of antigen transduction in this process ] . -
pubmed
Mouse mammary
tumor virus (
MMTV ) is known to infect heterologous cells but it does not appear that it alters their growth or morphological characteristics . -
pubmed
Djungarian hamster mammary tumor cells infected with
MMTV were found to increase the ability of the above cells to grow in semi - solid media . -
pubmed
[ Effects of medial preoptic area stimulation on the midbrain central gray related to
lordosis in female
rats ] . -
pubmed
These data suggest that in
patients with advanced
Parkinson ' s disease ,
L - dopa administration results in a smaller increase and a shorter duration of elevation in striatal
dopamine concentration than in controls . -
pubmed
These observations support the hypothesis that the " wearing - off " phenomenon that occurs during the treatment of
patients with
Parkinson ' s disease occurs as a consequence of a reduction in the rate of conversion of
L - dopa to
dopamine and perhaps diminished capacity for the storage of
dopamine . -
pubmed
Level and temporal pattern of naturally cytolytic cells during
acute Graft - versus - Host Disease (
GVHD ) in the
rat . -
pubmed
Acute lethal
GVHD was produced in either newborn or adult ( DA x LEW)F1
rats by iv injection of LEW spleen and lymph node ( LN ) cells . -
pubmed
At 7 , 14 , and 21 days after cell injection , the ability of non - adherent mononuclear cells from the LN , spleen , peripheral blood lymphocytes ( PBL ) , marrow , and thymus to kill 51Cr - labeled
dog ( DT-5 )
lymphoma , and undifferentiated
sarcoma ( 11031 ) or
human ( HUS-2 )
sarcoma cells in vitro was determined . -
pubmed
Cervical curve depth ( CCD ) was radiographically evaluated in 35
patients who presented with
cervical hypolordosis or
kyphosis (
CH / K ) . -
pubmed
The blood
glucose level of
rats with
streptozotocin (
STZ)-induced
diabetes has been found to be normalized by administration of
vanadyl or
vanadate complexes . -
pubmed
VPA was also effective for normalizing the blood
glucose level of
STZ - induced
diabetic rats when given intraperitoneally or orally . -
pubmed
Role of
sodium -
hydrogen exchange in the proliferation of immortalised lymphoblasts from
patients with essential
hypertension and normotensive subjects . -
pubmed
Similarly , expression of TGF - alpha mRNA and peptide has been shown to occur in various
human lung carcinomas in vivo and in vitro . -
pubmed
In an 8 - week , placebo - controlled multicenter study , the efficacy of dose levels of
simvastatin 2.5 , 5 , 10 , 20 , and 40 mg was evaluated in 166
patients with
hypercholesterolemia , of whom 163 completed the trial . -
pubmed
The ability of oxidative stress to induce apoptosis ( programmed cell
death ) , and the effect of
Trolox , a water soluble
vitamin E analog , on this induction were studied in vitro in
mouse thymocytes . -
pubmed
Two
patients with
schizophrenia had markedly abnormal neuroimaging studies ; one was found to have a large , cystic cavum vergae , while the other demonstrated complete
agenesis of the septum pellucidum with a monoventricular system . -
pubmed
Teaching was carried out by a Diabetes Nurse Educator within primary care health centres ( 141 patients ) and a hospital
diabetes clinic ( 17
patients ) . -
pubmed
Glucose-6 - phosphate isomerase deficiency associated with
nonspherocytic hemolytic anemia in the
mouse : an
animal model for the
human disease . -
pubmed
The first two mutations causing
hereditary glucose-6 - phosphate isomerase ( GPI ) deficiency associated with
chronic nonspherocytic hemolytic anemia in
nonhuman mammals are described in the
mouse . -
pubmed
In comparison with wild type , heterozygous
individuals exhibited neither hematologic differences nor alterations of other physiologic parameters , including plasma concentration of
glucose ,
pyruvate and
lactate ,
body weight , organo - somatic indices of liver , lung , kidney , spleen , and heart , as well as viability . -
pubmed
Homozygous
anemic mice showed
hepatosplenomegaly and typical adaptations to
hypoxia , such as an elevated heart - somatic index and , for one mutant line , an enhanced lung - somatic index . -
pubmed
Further , these
animals were characterized by a marked reduction of
body weight and an increase of lethality both correlated with the degree of
enzyme deficiency in tissues . -
pubmed
The latter findings were attributed to a reduced glycolytic capability of the whole
organism caused by the enzyme defect in tissues , rather than representing secondary consequences of
GPI deficiency in erythrocytes . -
pubmed
The similarity in physicochemical and kinetic properties of the mutant
murine proteins reported earlier with those of allozymes found in
human GPI deficiency , as well as the comparable metabolic and physiologic consequences of this enzyme defect in
mice and
humans support that these
murine mutants are excellent
animal models for the
human disease . -
pubmed
METHODS : We evaluated maternal reporting of
signs and symptoms 2 and 4 weeks after diagnosis among 271 Egyptian
children & lt ; 5 years old . -
pubmed
Children with
ARI were evaluated by physical examination , chest radiography , and
pulse oximetry , and were alternately assigned for a maternal interview about the episode 14 or 28 days later . -
pubmed
Outcome of respiratory symptoms after antireflux surgery on
patients with
gastroesophageal reflux disease . -
pubmed
DESIGN : A case series of
patients with
GERD and
respiratory symptoms undergoing fundoplication from 1987 to 1994 at a tertiary care university hospital . -
pubmed
PATIENTS : Of 118
patients undergoing fundoplication for cardinal symptoms of
GERD , 63 had respiratory symptoms . -
pubmed
RESULTS : Respiratory symptoms were present in 53 % ( 63/118 ) of
patients with
GERD . -
pubmed
Abnormalities of esophageal motility were present in 34 % ( 17/50 ) of the
patients , and these were significantly more common in patients who did not experience relief of their
respiratory symptoms ( 9/12 vs 8/38 , chi 2 = 9.54 , P = .002 ) . -
pubmed
CONCLUSIONS : Respiratory symptoms are common in
patients with
GERD . -
pubmed
Effect of left and right lateral decubitus positions on Doppler mitral flow patterns in
patients with severe
congestive heart failure . -
pubmed
Patients with severe
congestive heart failure (
SCHF ) complain of increasing
dyspnea when adopting left lateral decubitus ( LLD ) position that improves when turning over to the right lateral decubitus ( RLD ) position (
trepopnea ) . -
pubmed
This study analyzes the effect of RLD and LLD positions on LV filling pattern assessed by Doppler echocardiography in
patients with
SCHF . -
pubmed
Seventeen men and seven
women ( aged 56.22 + /- 18.52 years ) with
SCHF in New York Heart Association functional class III - IV and nine normal control subjects ( eight men and one woman aged 56.96 + /- 18.14 years ) were studied . -
pubmed
The objective of the present work was to study the effects of
tic disorder (
TD ) and
hyperactivity (
HA ) on slow cortical potentials in
children with combined TD +
HA symptoms . -
pubmed
Four groups of
children ( n = 10/11 in each group ) were studied : healthy controls , pure TD , pure
attention deficit hyperactivity disorder (
ADHD ) , and combined
tic and
hyperactivity symptoms . -
pubmed
Nevertheless , deviant patterns of scalp distribution were found for pure
ADHD patients , which suggested an inefficiency in involving the adequate task - related areas . -
pubmed
Human infection with the pathogenic tissue nematode
Onchocerca volvulus may result in a spectrum of clinical manifestations or in a putatively immune condition . -
pubmed
It was found that
Zn pretreatment ( I mg / kg
body weight as
ZnSO4 ) has a unique inhibitory effect on
IDDM development in MT - null
mice in contrast to no marked effect in control ( C57BL/6J )
mice , suggesting that
Zn ions free from MT molecules exerted this protective effect . -
pubmed
The highest
Zn dose ( 10 mg / kg
body weight ) fully suppressed development of
hyperglycaemia in both types of
mice . -
pubmed
Infection by hepatitis C viruses (
HCVs ) is a serious medical problem with no broadly effective treatment available for the progression of
chronic hepatitis . -
pubmed
Male BXSB
mice , unlike female BXSB , develop a severe early onset
lupus - like disease that has been linked to an intrinsic B cell defect . -
pubmed
A less marked and later
lymphocytopenia was also shown in
subjects affected by
chronic renal insufficiency ( 2907 + /- 726 t 0 ; 1944 + /- 512 t 180 minutes , p & lt ; 0.005 ) . -
pubmed
Conyza floribunda ,
Eupatorium articulatum ,
Bonafousia longituba ,
Bonafousia sananho ,
Tagetes pusilla and
Piper lenticellosum extracts showed a significant antiinflammatory activity in vivo in the carrageenan - induced paw
oedema model in
mice . -
pubmed
Re : "
Tobacco as a cause of
lung cancer : some reflections " . -
pubmed
RESULTS : Twenty - eight
patients ( 2.5 % ) had
intraoperative complications related to the vena cava preservation technique , which were treated during the operation . -
pubmed
Eleven
patients ( 1 % ) had early
postoperative complications ( first week ) , the most frequent ( nine cases ) being an acute
Budd - Chiari syndrome in the first 48 hr . -
pubmed
Three
patients developed symptoms of massive
ascites between 2 and 3 months ( late
postoperative complications ) , with patency of the retrohepatic cava verified by cavography . -
pubmed
This chronic
Budd - Chiari syndrome was controlled in all
patients with diuretics . -
pubmed
Anti - inflammatory activity of phycocyanin extract in
acetic acid - induced
colitis in
rats . -
pubmed
The anti - inflammatory effect of c - phycocyanin extract was studied in
acetic acid - induced
colitis in
rats . -
pubmed
was administered 30 min gbefore induction of
colitis with enema of 1 ml of 4 %
acetic acid per
rat . -
pubmed
Human astrovirus (
HAstV ) is a significant cause of
acute diarrhea among children , resulting in outbreaks of
diarrhea and occasionally in hospitalization . -
pubmed
Improved detection methods for eight antigenic types of
HAstV and studies assessing the frequency and severity of
HAstV diarrhea have further defined the impact of
HAstV infections in children . -
pubmed
However , frequent
coinfection of
HAstV with rotavirus and caliciviruses in childhood
diarrhea complicates the epidemiology . -
pubmed
STUDY OBJECTIVES : Respiratory muscle strength has been shown to be reduced in
patients with chronic
heart failure . -
pubmed
The purpose of this prospective study was to determine whether long - term therapy with the
angiotensin - converting enzyme ( ACE ) inhibitor perindopril improves respiratory muscle strength in
patients with chronic
heart failure . -
pubmed
PATIENTS AND METHODS : Eighteen
patients with stable chronic
heart failure were administered
perindopril , 4 mg / d , in addition to their standard therapy for a period of 6 months . -
pubmed
A 7 - month - old , neutered female
Labrador Retriever was evaluated for
tetraparesis and subtle
cerebellar dysfunction . -
pubmed
This disease and its relation to similar
human heritable
leukodystrophies are discussed . -
pubmed
DESIGN : Two hundred and sixty - eight pregnant
women with
type 1 diabetes mellitus were recruited . -
pubmed
Latent
infection of
human ganglia with
Varicella - Zoster virus (
VZV ) is characterized by a highly restricted pattern of viral gene expression . -
pubmed
At the later time points after
infection the RNA transcripts expressed most frequently were those for
VZV genes 21 , 62 , and 63 . -
pubmed
Management of
hydrocephalus in pediatric
patients with
posterior fossa tumors : the role of endoscopic third ventriculostomy . -
pubmed
OBJECT : The authors undertook a study to evaluate the effectiveness of endoscopic third ventriculostomy in the management of
hydrocephalus before and after surgical intervention for
posterior fossa tumors in
children . -
pubmed
METHODS : Between October 1 , 1993 , and December 31 , 1997 , a total of 206 consecutive
children with
posterior fossa tumors underwent surgery at Hjpital Necker - Enfants Malades in Paris . -
pubmed
The medical records and neuroimaging studies of the remaining 196
patients were reviewed and categorized into three groups : Group A , 67
patients with
hydrocephalus present on admission in whom endoscopic third ventriculostomy was performed prior to
tumor removal ; Group B , 82
patients with
hydrocephalus who did not undergo preliminary third ventriculostomy but instead received conventional treatment ; and Group C , 47
patients in whom no
ventricular dilation was present on admission . -
pubmed
There were no significant differences between
patients in Group A or B with respect to the following variables : age at presentation , evidence of
metastatic disease , extent of
tumor resection , or follow - up duration . -
pubmed
In
patients in Group A , however , more severe
hydrocephalus was demonstrated ( p & lt ; 0.01 ): the
patients in Group C were in this respect different from those in the other two groups . -
pubmed
Ultimately , there were only four
patients ( 6 % ) in Group A compared with 22
patients ( 26.8 % ) in Group B ( p = 0.001 ) in whom progressive
hydrocephalus required treatment following removal of the
posterior fossa tumor . -
pubmed
The other six
patients ( 7.3 % ) were treated by endoscopic third ventriculostomy after
tumor resection . -
pubmed
In Group C , two
patients ( 4.3 % ) with
postoperative hydrocephalus underwent endoscopic third ventriculostomy . -
pubmed
Although the authors acknowledge that the routine application of third ventriculostomy in selected
patients results in a proportion of
patients undergoing an " unnecessary " procedure , they believe that because
patients ' postoperative courses are less complicated and because the incidence of morbidity is low and the success rate is high in those
patients with severe
hydrocephalus that further investigation of this protocol is warranted . -
pubmed
Surgery for giant
intracranial aneurysms not operable using standard neurosurgical techniques was performed in 8
patients . -
pubmed
PURPOSE : The aim of this study was to investigate changes in quality of life ( QOL ) among medically inoperable Stage I
non - small - cell lung cancer (
NSCLC )
patients treated with curative radiotherapy . -
pubmed
PATIENTS AND METHODS : The study sample was composed of 46
patients irradiated for Stage I
NSCLC . -
pubmed
None of the locally treated
patients developed regional
recurrence . -
pubmed
Significantly higher levels of
dysphagia , which persisted up to 12 months , were observed in those in which the regional lymph nodes were treated , as compared to the locally treated
patients . -
pubmed
Taking into account the low incidence of regional
recurrences after local irradiation , the higher incidence and severity of radiation - induced changes , and the higher levels of
dysphagia persisting up to 12 months , local irradiation of the primary
tumor without elective irradiation of the regional lymph nodes may be the most appropriate treatment for
patients with small , peripherally located
tumors . -
pubmed
OBJECTIVE : The purpose of this study was to investigate the relationship between blood pressure that is measured with the automated blood pressure monitor , Omron HEM-705CP ( Omron Corporation , Tokyo , Japan ) , and
mercury sphygmomanometry in normotensive and
preeclamptic pregnant
women . -
pubmed
After routine
mercury blood pressure recordings that were taken by midwives , women with
preeclampsia ( n = 45
women ) measured their own blood pressure using an Omron HEM-705CP monitor ( n = 212 recordings ) . -
pubmed
METHODS : Argon plasma coagulation was applied in 13
children ( age 0.05 - 17 years ; median 3 years ) with significant comorbid conditions including immunosuppression , chemotherapy , acute or
chronic organ failure , and
coagulopathy . -
pubmed
Blood loss and transfusion requirement were reduced in 3 of the other 4
patients . -
pubmed
Complications occurred in 2 of 13
patients and included submucosal argon gas and
scar formation . -
pubmed
A male
patient underwent hepatectomy for removal of metastatic
tumors from
colon cancer . -
pubmed
CASE PRESENTATION : A 34 - year - old
man had a sudden onset of severe
headache . -
pubmed
The
patient had an uneventful postoperative course and his
neurologic symptoms were improved . -
pubmed
BACKGROUND :
Porphyromonas gingivalis , a key pathogen in
periodontitis , is able to adhere to and invade the pocket epithelium . -
pubmed
gingivalis serotypes ( 6 capsular types and non - encapsulated
strains ) was compared on in vitro cultured epithelial monolayers from
periodontal pockets of
patients with
periodontitis . -
pubmed
gingivalis to
human periodontal pocket epithelial cells . -
pubmed
Heterotopic ossification in the
ischemic kidney of the
rabbit ,
rat and
guinea pig . -
pubmed
CONCLUSION : The observed decreasing trend in
oral cancers in Indian men may be attributed to a decrease in the usage of pan and
tobacco . -
pubmed
Oats , antioxidants and endothelial function in
overweight ,
dyslipidemic adults . -
pubmed
OBJECTIVE : To determine effects of oat and antioxidant vitamin ( C 500 mg , E 400 IU ) ingestion on endothelial function in
overweight , dyslipidemic
adults . -
pubmed
Atypical antipsychotics are not well studied in the treatment of elderly
patients with
functional psychosis . -
pubmed
Secondary end points included changes in mean serum
creatinine and estimated GFR ( Cockroft and Gault , CG ) over time , incidence of
infection , cardiovascular risk factors ( blood pressure ,
cholesterol ) , graft and
patient survival rates , as well as incidence of biopsy - proven
chronic allograft nephropathy (
CAN ) . -
pubmed
Biopsy - proven
CAN was diagnosed in 2 control
patients ( 10 % ) at 6 to 8 months ' posttransplant . -
pubmed
Twenty - one
patients were treated in the Pacific Voice Clinic with trancutaneous injection of
CaHA for
vocal cord paralysis ( n = 19 ) and
vocal scarring ( n = 2 ) . -
pubmed
We report here that , in
C57BL / 6 mice , the recruitment of naive lymphocytes is impaired in LNs draining a
B16 melanoma tumor . -
pubmed
Cabbage and
wheat was more susceptive to
AlCl3 toxicity under acid than under neutral condition , while
radish was in adverse . -
pubmed
MATERIALS AND METHODS : Thirty - two pregnant
patients with the diagnosis of
malignancy were followed . -
pubmed
CONCLUSION : The
cancer treatment took into full consideration the specific condition of each pregnant
patient . -
pubmed
Nine
patients ( 10 eyes ) with complicated , refractory primary and secondary
open - angle glaucoma are discussed . -
pubmed
An elderly
woman presented with her third episode of
back pain ,
fever and
neurological deficits . -
pubmed
Herpes zoster virus (
HZV ) reactivation is commonly reported in elderly or immune compromised patients . -
pubmed
In a 43 - year - old
man admitted due to episodes of
syncope , the diagnosis of
LD was delayed -- after pacemaker implantation -- when he developed joint and neurological symptoms . -
pubmed
In the second case of a 26 - year - old
woman , presenting on admission with
fatigue and flu - like symptoms , ECG showed
CHB with a stable escape rhythm of about 52 / min . -
pubmed
Malaria has been a major selective force on the
human population , and several erythrocyte polymorphisms have evolved that confer resistance to severe
malaria . -
pubmed
A 76 - year - old
man was referred to our hospital because of
memory impairment . -
pubmed
After 6 months of treatment , the scores on verbal fluency (
animals and vegetables/60 seconds ) and frontal assessment battery of the
patient improved despite no significant changes on the Mini - Mental State Examination and
Alzheimer ' s Disease Assessment Scale . -
pubmed
Systemic reaction to
leucovorin in a
child with
lymphoblastic lymphoma suggestive of
hypersensitivity . -
pubmed
Honokiol is an active compound purified from
magnolia that has been shown to induce cell differentiation , apoptosis , and anti - angiogenesis effects , as well as an enhancement in
tumor growth delay in combination with chemotherapeutic agents in several
mouse xenograft models . -
pubmed
For an in vivo study ,
Lewis lung carcinoma - bearing
C57BL / 6 mice were treated with either liposomal
honokiol at 25 mg / kg or 5 Gy of single
tumor radiation , or a combination of both over 12 days of treatment . -
pubmed
Amino acid biosynthesis deficiency in bacteria associated with
human and animal hosts . -
pubmed
METHODS : Thirty - two consecutive
patients with pathologically proven
hilar cholangiocarcinomas were evaluated by both low mechanical index CEUS and CECT . -
pubmed
OBJECTIVES : To make a contribution to the treatment modality of
larynx cancer , we evaluated our surgical outcomes of the
patients with
larynx cancer and their quality of life in the postoperative period . -
pubmed
PATIENTS AND METHODS : Forty - three
patients ( 38
males , 5
females ; mean age 57.6 years ; range 34 to 84 years ) with
larynx cancer were included in this retrospective clinical study . -
pubmed
The
patients were evaluated with respect to age , sex , smoking ,
alcohol consumption , localization - differentiation - stage of the
tumor , surgery and RT ,
postoperative complications and survival . -
pubmed
RESULTS : The most frequent
postoperative complication was
pharyngocutaneous fistula ( 41.3 % ) , which occurred only in TL / NTL
patients . -
pubmed
We emphasize that multi - institutional prospective quality of life studies comparing different treatment methods for similar stage
tumors are essential in defining the optimal management strategy in
patients with
larynx cancer . -
pubmed
A 45 - year - old
woman presented with left - side pulsating
tinnitus ,
autophony and disequilibrium . -
pubmed
Furthermore , we show that beta toxin strongly stimulates biofilm formation in vivo as demonstrated by a role in causation of
infectious endocarditis in a
rabbit model . -
pubmed
Although there is still no consensus on the treatment of
individuals with asymptomatic
hyperuricemia , it is time to reappraise potential approaches for these subjects with regard to prevention of
hypertension and related
renal and cardiovascular complications . -
pubmed
In this study ,
ischemia induction for 18 min in male
New Zealand White rabbits resulted in the highest percentage ( 80 % ) of biphasic paraplegic outcome assessed by Tarlov 's score . -
pubmed
With improvement in
leukemia therapy ,
central nervous system ( CNS ) tumors are the leading cause of
cancer mortality in
children and the most expensive of all
human neoplasms to treat . -
pubmed
Therefore , considering the complex physiology of solid
tumors and in order to inform simulations well , we did experiments on Balb / c
mice using non - invasive fluorescence spectroscopy to have a feedback of
protoporphyrin IX (
PpIX ) concentration in
tumor just before irradiation and during treatment . -
pubmed
Atrial fibrillation , the most common cardiac complication of
hyperthyroidism , occurs in an estimated 10 % to 25 % of overtly
hyperthyroid patients . -
pubmed
Herein , we review the medical literature and examine the evidence behind the recommendations in order to determine the best approach to
thromboembolic prophylaxis in
patients who have
atrial fibrillation that is associated with
hyperthyroidism . -
pubmed
METHODS : Eighteen
cases with left peripheral facial
paralysis were randomly divided into a Hegu group , a Dicang group and a Houxi group , 6 cases in each group . -
pubmed
PATIENTS / METHODS : We studied 241
patients , including 162 after
ischemic stroke and 79 after
transient ischemic attack (
TIA ) , recruited 6 months to 4 years ( median , 36 months ) after the events . -
pubmed
After starting of
prednisone treatment
anemia ,
thromocytopenia and the
patient 's performance status rapidly improved . -
pubmed
Linkage study of
embryopathy - polygenic inheritance of
diabetes - induced
skeletal malformations in the
rat . -
pubmed
We developed an inbred
rat model of
diabetic embryopathy , in which the offspring displays
skeletal malformations (
agnathia or
micrognathia ) when the mother is
diabetic , and no malformations when she is not
diabetic . -
pubmed
We contrasted the fetal outcome in inbred Sprague - Dawley L
rats ( 20 %
skeletal malformations in
diabetic pregnancy ) with that of inbred Wistar Furth
rats ( denotedW , no
skeletal malformations in
diabetic pregnancy ) . -
pubmed
We conclude that the genetic involvement in
rodent diabetic embryopathy is polygenic and predisposing for
congenital malformations . -
pubmed
Five
patients with extensive lower abdominal wall disruption following
traumatic injuries or
infection were treated using a novel flap for functional reconstruction . -
pubmed
The innervated TFL osteomyocutaneous flap is an ideal option for lower abdominal reconstruction in
patients with complex
abdominoperineal defects with
loss of bony integrity . -
pubmed
METHODS : Corneas of
patients with
Fuchs ' dystrophy were examined prospectively before and at intervals through 2 years after DSEK . -
pubmed
Protective effects of
vitamins E , B and C and
L - carnitine in the prevention of
cisplatin - induced
ototoxicity in
rats . -
pubmed
CONCLUSION :
Vitamins B , E and C and
L - carnitine appear to reduce
cisplatin - induced
ototoxicity in
rats . -
pubmed
The use of such additional treatments to decrease
cisplatin - induced
ototoxicity in
humans is still under discussion . -
pubmed
STUDY OBJECTIVES : The purpose of this study was to determine if
subjects with moderate - to - severe
obstructive sleep apnea would experience increasing treatment effect when a tongue retention component was added to a mandibular repositioning appliance . -
pubmed
PATIENTS : Forty - four sequentially recruited
patients with moderate - to - severe
obstructive sleep apnea . -
pubmed
PATIENTS AND METHODS : 60
patients with
visceral obesity were randomly assigned to either receive 9 g of
L - arginine or placebo for 3 months . -
pubmed
OBJECTIVE : The aim of our study was to examine the 30 - day and 1 - year survival rate for
patients undergoing percutaneous coronary artery intervention ( PCI ) of unprotected left main ( ULM )
stenosis by the presence (
acute myocardial infarction [
AMI ] group ) or absence ( non - AMI group ) of
AMI at the time of hospital admission . -
pubmed
METHODS : We retrospectively reviewed 64
patients undergoing PCI of ULM
stenosis at our regional heart institute between 2000 and 2008 . -
pubmed
RESULTS : Thirty - six
men and 28
women underwent PCI for ULM
stenosis . -
pubmed
Thirty - three
patients ( 51.6 % ) presented with
AMI . -
pubmed
CONCLUSIONS : We found that
AMI at presentation was significantly associated with higher mortality in
patients undergoing ULM stenting . -
pubmed
Perseverative behavior in
rats with
methamphetamine - induced
neurotoxicity . -
pubmed
Infection of Mexican lime trees (
Citrus aurantifolia L. ) with the specialized bacterium "
CandidatusPhytoplasma aurantifolia " causes witches ' broom disease . -
pubmed
Respiratory disease due to current
egg drop syndrome virus in
Pekin ducks . -
pubmed
Severe acute respiratory symptoms with
coughing ,
dyspnea , and gasping were reported in two flocks of 9 - day - old
Pekin ducklings from different provinces . -
pubmed
Reproducibility of microvolt T - wave alternans in
patients with
ischemic heart disease . -
pubmed
Forty - two postmenopausal
women with
osteoporosis and thirty seven age and
BMI - matched healthy postmenopausal
women were included in the study . -
pubmed
A comparison of spectral quality in magnetic resonance spectroscopy data acquired with and without a novel EPI - navigated PRESS sequence in school - aged
children with
fetal alcohol spectrum disorders . -
pubmed
Association between bioimpedance analysis parameters and
left ventricular hypertrophy in peritoneal dialysis
patients . -
pubmed
In this study , we aimed to determine the impact of blood pressure measurements and volume status determined by bioelectrical impedance analysis ( BIA ) measurements over
left ventricular hypertrophy (
LVH ) in
PD patients . -
pubmed
METHODS : Thirty - one prevalent
PD patients were enrolled . -
pubmed
Patients with a documented
cardiovascular disease and uncontrolled
hypertension were excluded . -
pubmed
Fifty - eight percent of
patients had
LVH . -
pubmed
CONCLUSIONS : We want to underline that , besides maintaining residual renal function , strict blood pressure control , particularly diastolic blood pressure , and avoiding
hypervolemia and
abdominal obesity should be main clinical goals in follow - up of
PD patients in order to prevent
LVH progression . -
pubmed
33
volunteers drove for 90 min on a rural road during the afternoon and night in an instrumented car , while electroencephalography and electrooculography and lane departures were recorded continuously and subjective ratings of
sleepiness were made every 5 min ( Karolinska Sleepiness Scale - KSS ) . -
pubmed
Synthesis and
cytotoxic activity evaluation of novel
arylpiperazine derivatives on
human prostate cancer cell lines . -
pubmed
The in vitro
cytotoxic activities of all synthesized compounds against three
human prostate cancer cell lines (
PC-3 ,
LNCaP , and
DU145 ) were evaluated by a CCK-8 assay . -
pubmed
However , these compounds also exhibited
cytotoxicity towards
human epithelial prostate normal cells
RWPE-1 . -
pubmed
infections in
horses from northern and central Kazakhstan . -
pubmed
A cross - sectional survey was performed to obtain current data on the
gastrointestinal myiasis of
horses in the provinces of Kostanay , Akmola and Karagandy , northern and central Kazakhstan . -
pubmed
Evaluation of nanoformulated therapeutics in an ex - vivo
bovine corneal irritation model . -
pubmed
METHODS : The
bovine cornea obtained were subjected to the 0.5N
NaOH insult that induced alkali
burn and
inflammation as observed in the in vivo situation . -
pubmed
METHODS : Thirty - two
patients with primary
ACL deficiency were analysed by a navigation system immediately before and after each of the two reconstructions . -
pubmed
UNBLOCK : an open - label , dose - finding , pharmacokinetic and safety study of
bivalirudin in
children with
deep vein thrombosis . -
pubmed
PATIENTS / METHODS : The UNBLOCK ( UtilizatioN of BivaLirudin On Clots in Kids ) study was an open - label , single - arm , dose - finding , pharmacokinetic , safety and efficacy study of
bivalirudin for the acute treatment of
deep vein thrombosis (
DVT ) in
children aged 6 months to 18 years . -
pubmed
At 48 - 72 h , nine ( 50 % )
patients had complete or partial
thrombus resolution , increasing to 16 ( 89 % ) at 25 - 35 days . -
pubmed
CONCLUSIONS :
Bivalirudin demonstrated reassuring safety and noteworthy efficacy in terms of early clot resolution in
children and
adolescents with
DVT . -
pubmed
Although a widely available and familiar monitoring tool , the APTT correlates poorly with plasma
bivalirudin concentration , possibly limiting its utility in managing pediatric
patients receiving
bivalirudin for
DVT . -
pubmed
Lamotrigine (
LTG ) is commonly used to control
seizure in
epilepsy patients and with referenced therapeutic windows in clinical practice . -
pubmed
This study is to identify and characterize the function of genetic variants that influence the trough concentrations of
LTG in
epilepsy patients following monotherapy regimen ( 37.5 - 250 mg / d ) . -
pubmed
Our findings have important implications for the rational overcoming of drug resistance in individual
leukemia patients . -
pubmed
Methodology and technique advancements facilitated the early diagnosis of
AD leading to a shift toward preclinical
AD stages investigation in order to delay the disease onset in
individuals at risk for
AD . -
pubmed
Due to these promising results , an emerging field of studies is currently investigating the efficacy of interventions addressing different lifestyle habits in cognitive intact elderly
individuals as a potential preventive strategy against
AD onset . -
pubmed
PATIENTS AND METHODS : In a prospective study of 55
patients ( 30 m , 25 f , age 16 - 77 years ) with a
chronic rhinosinusitis with or without
polyps combined with a
deformity of the outer nose we performed a FESS together with a SRP using a closed or open approach . -
pubmed
Effect of chemoradiotherapy on nutrition status of
patients with
nasopharyngeal cancer . -
pubmed
We aimed to assess the effect of chemoradiotherapy on the nutritional status of
patients with
nasopharyngeal cancer (
NPC ) and to detect the risk factors for poor nutrition status in
NPC patients after radiotherapy . -
pubmed
A total of 104
NPC patients participated in this clinical observational study . -
pubmed
After radiotherapy , 20.19 % of
patients had more than 10 %
weight loss . -
pubmed
Radiotherapy affects the nutritional status of
NPC patients . -
pubmed
OBJECTIVE : To retrospectively analyze the clinical , radiologic , and endoscopic characteristics of small
bowel cancer patients in Thailand 's Siriraj Hospital . -
pubmed
MATERIALS AND METHODS : This retrospective analysis included 185 adult
patients ( 97
men , 88
women ; mean age = 57.6 + -14.9 ) with pathologically confirmed small bowel
cancer diagnosed between January 2006 and December 2013 . -
pubmed
RESULTS : Of the 185
patients analyzed ,
gastrointestinal stromal tumor (
GIST ) was the most common diagnosis ( 39.5 % , n=73 ) . -
pubmed
RESULTS : A 41 - year - old
woman was referred with a 2 - week history of
decreased vision and
scotoma in the left eye . -
pubmed
BACKGROUND :
Human immunodeficiency virus (
HIV ) Rapid diagnostic Test ( RDT ) kits are the preferred assays for
HIV testing in many countries . -
pubmed
Little is known about the diagnostic characteristics of First Response
HIV-1 - 2 RDT kit , used as a single test kit in national
HIV prevention and control programmes . -
pubmed
BACKGROUND :
Patients with bilateral
hip disease may undergo same - day or staged bilateral total hip arthroplasty ( THA ) . -
pubmed
Patients with subsequent
PJI were identified . -
pubmed
In this regard , somatic genetic evaluation of
tumors is useful in not only predicting response to initial targeted therapies but also in anticipating and guiding therapy after the development of acquired resistance ; therapeutic drug monitoring of novel small molecules and monoclonal antibodies must be incorporated in our day - to - day practice to minimize the negative effect on clinical outcome of interindividual variability on pharmacokinetic processes of these drugs for all patients , but especially for fragile
patient populations and those with
organ dysfunction or comorbidities . -
pubmed
METHODS : From October 2014 to August 2015 , 153
patients with early - stage
non - small - cell lung carcinoma (
NSCLC ) and benign disease underwent uniportal subxiphoid VATS major lung resections . -
pubmed
RESULTS : Of the 153
patients who underwent surgery with the uniportal subxiphoid VATS approach , 105 had lobectomies and 48 had segmental resections ; 135 cases of
lung cancer and 18 cases of benign
pulmonary disease were noted . -
pubmed
In
patients with
lung cancer , the mean total number of lymph node stations explored was 3.4 + - 0.8 . -
pubmed
Three of these six patients who became re - infected with
HBV experienced
HCC recurrence after LT . -
pubmed
The
HBV DNA reappearance rate was significantly higher in patients with
HCC recurrence after LT ( p & lt ; 0.001 ) . -
pubmed
HCC recurrence and mutations in the
HBV S gene were associated with
HBV reinfection after LT . -
pubmed
CONCLUSIONS : In
workers exposed to low levels of MDI and solvents in
polyurethane shoe sole production there was a high prevalence of
cough and
nasal congestion . -
pubmed
Nonkeratinizing
Squamous Cell Carcinoma In Situ of the Upper Aerodigestive Tract : An
HPV - Related Entity . -
pubmed
The clinical and pathologic characteristics of
human papillomavirus (
HPV)-related
premalignant lesions in the upper aerodigestive tract have not been adequately studied . -
pubmed
There are a few reports of oral cavity
HPV - related severe
dysplasia with unique morphology ( prominent apoptosis / karyorrhexis imparting a ' bowenoid ' appearance ) and a single case report of
HPV - related squamous cell carcinoma in situ with nonkeratinizing histology distinct from the ' bowenoid ' pattern that extensively involved the upper aerodigestive tract . -
pubmed
The aim of this study was to characterize the morphologic and clinical features of
HPV - related severe
dysplasia /
carcinoma in situ . -
pubmed
Thus , nonkeratinizing morphology was a strong predictor of transcriptionally - active
HPV in severe
dysplasia /
carcinoma in situ . -
pubmed
Moreover ,
Cu - BGNs showed no significant
cytotoxicity towards
human mesenchymal stem cells and fibroblast cells at concentrations of 100 , 10 and 1mug / mL. -
pubmed
In the present study , an in vitro study model for tumour - induced DC dysfunction was established by culturing DCs with pooled sera from multiple
non - small cell lung cancer (
NSCLC )
patients . -
pubmed
Head and pelvic movement asymmetries at trot in riding
horses in training and perceived as free from
lameness by the owner . -
pubmed
Recent studies evaluating
horses in training and considered free from
lameness by their owners have identified a large proportion of
horses with motion asymmetries . -
pubmed
In a cross - sectional study , vertical head and pelvic movement symmetry was measured in 222 Warmblood type riding
horses , all without perceived performance issues and considered free from
lameness by their owners . -
pubmed
A large proportion ( 72.5 % ) of
horses in training which were perceived as free from
lameness by their owner showed movement asymmetries above previously reported asymmetry thresholds during straight line trot . -
pubmed
We present a series of five
patients with
appendiceal intussusception and discuss features that may direct the pediatric surgeon to achieve early recognition and provide optimal treatment . -
pubmed
MATERIALS AND METHODS : The database of a tertiary medical center was retrospectively reviewed for all
patients treated for
appendiceal intussusception during the period from January 1995 to January 2016 . -
pubmed
Although
patients with indolent
B - cell lymphomas have a relatively good survival rate , conventional chemotherapy is not curative . -
pubmed
Patients affected with
urolithiasis ,
HIV infection ,
tumors , and vascular and chronic
inflammatory bowel diseases were excluded . -
pubmed
The inability to propagate
human prostate epithelial cells indefinitely has historically presented a serious impediment to
prostate cancer research . -
pubmed
We have previously reported that prostate
CRCs form functional prostate glands when implanted under the
mouse renal capsule . -
pubmed
CASE DESCRIPTION : A healthy 29 - year - old
female presented with intermittent right facial
numbness . -
pubmed
Effect of the dietary
polyacetylenes falcarinol and
falcarindiol on the gut microbiota composition in a
rat model of
colorectal cancer . -
pubmed
OBJECTIVES :
( 3R )- Falcarinol (
FaOH ) and
( 3R,8S )- falcarindiol (
FaDOH ) have previously been shown to reduce the number of
neoplastic lesions and the growth rate of
polyps in the colon of
azoxymethane (
AOM ) treated
rats . -
pubmed
Comparison of the gut microbiota of
rats who developed large
neoplasms in the colon with
rats without large
neoplasms showed that the gut microbiota was significantly different in
rats who developed large
colon neoplasms compared to
rats with no macroscopic
colon neoplasms . -
pubmed
A 38 - year - old
woman was suffering from back , right arm , and
ankle joint pain , and visited our emergency department . -
pubmed
The
patient was diagnosed with mixed phenotype lineage
acute leukemia , treated immediately , and achieved remission . -
pubmed
Background : Cross - facial nerve graft is considered the treatment of choice for facial reanimation in
patients with
unilateral facial palsy caused by central facial
nerve damage . -
pubmed
Methods : In this study , cross - facial nerve graft with the sural nerve was planned for three
patients with
facial palsy through an intraoral approach . -
pubmed
Results :
DR3 deficiency was associated with restoration of a homeostatic mucosal immunostat in
SAMP mice through the regulation of several pro- and anti - inflammatory genes . -
pubmed
The present study compared the efficacy and safety of the HPG - HA dual - polymer formulation vs a
sodium hyaluronate ( SH)-containing artificial - tear formulation in
patients with
DED . -
pubmed
BACKGROUND :
Hepatitis B (
HBV ) transmission may result from in utero transmission . -
pubmed
We aimed to determine the correlation between maternal serum and umbilical cord blood
HBV DNA levels in infants delivered by chronic
HBV - infected mothers and to describe the effect of
cord blood viremia on vertical transmission . -
pubmed
HBeAg + ve mothers were younger with higher
HBV and cord
viremia . -
pubmed
Infants delivered by
HBeAg positive mothers and mothers with high
HBV DNA of more than 6 LOG IU / mL ( 1 x 106 IU / mL ) have increased relative risk of cord blood
viremia . -
pubmed
Several compounds showed promising activity against
TBEV ( EC50 0.35 - 0.91 muM ) , but the activity was accompanied by pronounced
cytotoxicity . -
pubmed
The Effect of Combined Patching and
Citalopram on Visual Acuity in
Adults with
Amblyopia : A Randomized , Crossover , Placebo - Controlled Trial . -
pubmed
Nonhuman animal models have demonstrated that selective
serotonin reuptake inhibitors ( SSRIs ) can enhance plasticity within the mature visual cortex and enable recovery from
amblyopia . -
pubmed
Remodeling of the
Caenorhabditis elegans non - coding RNA transcriptome by heat
shock . -
pubmed
While the transcriptional response of PCGs to
HS has been comprehensively analyzed in a variety of
organisms , the effect of this stress on the expression of non - coding RNAs ( ncRNAs ) has not been systematically examined . -
pubmed
Autologous stem cell transplant ( ASCT ) is the standard of care for
patients with
multiple myeloma (
MM ) . -
pubmed
Here we evaluated T cell transcriptional messenger RNA profiles and immunophenotypes to correlate immunologic senescence , exhaustion , and anergy with clinical endpoints in a cohort of
patients with
MM undergoing ASCT . -
pubmed
In this report , we announce the first whole - genome sequencing of six
strains of
Salmonella enterica isolated from imported meat in Algeria . -
pubmed
Incidence and risk factors for major
infections in hospitalized
children with
nephrotic syndrome . -
pubmed
INTRODUCTION :
Children with
nephrotic syndrome are at increased risk of
infections because of disease status itself and use of various immunosuppressive agents . -
pubmed
This study aimed to determine the incidence , spectrum , and risk factors for major
infections in hospitalized
children with
nephrotic syndrome . -
pubmed
METHODS : All consecutive hospitalized
children between 1 - 12 years of age with
nephrotic syndrome were enrolled in the study . -
pubmed
Children with acute
nephritis , secondary
nephrotic syndrome as well as those admitted for diagnostic renal biopsy and intravenous
cyclophosphamide or rituximab infusion were excluded . -
pubmed
Incidence of major
infections in hospitalized
children with
nephrotic syndrome was 43.8 % . -
pubmed
Streptococcus pneumoniae ( n = 9 ) was the predominant organism isolated in children with
peritonitis and
pneumonia . -
pubmed
As
Pneumococcus was the most prevalent cause of
infection in those children , attention should be paid to the
pneumococcal immunization in
children with
nephrotic syndrome . -
pubmed
A 43 - year - old
man with a history of pedestrian - truck collision 18 months prior presented with right - sided
abdominal pain and
chills . -
pubmed
A 50 year - old
woman presented with
hypoxemia and echocardiographic findings consistent with
pulmonary hypertension and
cor pulmonale . -
pubmed
PTTM is a rare entity that must be considered in
cancer patients with unexplained
hypoxemia ,
pulmonary hypertension and
lung opacities on imaging . -
pubmed
Although structural variations in this organization are an important source of natural genetic diversity ,
cytogenetic aberrations can also underlie a number of
human diseases and disorders . -
pubmed
Volume overload is the most common complication in
end - stage renal disease (
ESRD )
patients , being directly related to numerous complications including resistant
hypertension ,
cardiac hypertrophy ,
congestive heart failure or arterial stiffness , among others . -
pubmed
: We studied three
boys with
primary adrenal failure and
hypogonadotropic hypogonadism presenting at different ages at the Paediatric Endocrinology Clinic . -
pubmed
MATERIALS AND METHODS : We retrospectively reviewed medical records of
patients with suspected
HL at Kitasato University Hospital in 2017 and 2018 . -
pubmed
Case Report : We presented a 3 year - old
boy having recurrent
seizures since 2 years old and diagnosed as
epilepsy and treated with multiple antiepileptic drugs . -
pubmed
The
patient was
hypotonic and neurodevelopmentally poor . -
pubmed
The
patient was stable on an oral maintenance dose of
magnesium oxide with borderline blood
magnesium levels without
hypocalcemia . -
pubmed
The co - existing
fatty liver may affect the efficacy of anti -
HBV therapy and increase the all - cause mortality rates in patients . -
pubmed
The impact of immune -
inflammation - nutritional parameters on the prognosis of
non - small cell lung cancer patients treated with
atezolizumab . -
pubmed
METHODS : Twenty - five
patients with
depression were randomised to either
ketamine ( 0.5 mg / kg ) or
midazolam ( 0.045 mg / kg ) infusions over 40 min . -
pubmed
Patients reported preoperative unilateral
low - back pain and
weakness when flexing the hip . -
pubmed
Since the light / dark assay has historically been used to investigate
anxiety - like responses in
animals , we measured
anxiety in a light - independent open field assay and asked if stimulation of a brain region , the periaqueductal gray , that induces
anxiety would yield similar results to posterior thalamic stimulation . -
pubmed
Benefits and Harms of Long - term
Opioid Dose Reduction or Discontinuation in
Patients with
Chronic Pain : a Rapid Review . -
pubmed
A 61 - year - old
woman with a history of
primary aldosteronism caused by unilateral
hyperplasia of the adrenal gland presented with a 2 - week history of redness and severe
pain in the right thumb and thenar regions . -
pubmed
Hence , we diagnosed the
patient with
erythromelalgia caused by
polycythemia vera . -
pubmed
MATERIALS AND METHODS : 15 healthy controls and 33
patients with long duration ( > = 20 years )
type 1 Diabetes Mellitus (
T1DM ) were recruited . -
pubmed
Diabetic
subjects were classified into two groups :
T1DM , constituted by 14 non - retinopathic
patients , and
T1DM+RD , constituted by 19
patients in any stage of
diabetic retinopathy . -
pubmed
Erythrocyte plasmatic membranes of
RD patients were found to be more fluid ( GP : 0.43 + -0.03 ) than non - RD
patients ( GP : 0.40 + -0.04 ) with a statistically significant difference ( p = 0.035 ) . -
pubmed
Effect of
Toremifene on Endometrium and Neurocognitive Function in
Patients with
Breast Cancer Based on Resting State Functional MRI . -
pubmed
Methods : A total of 100
patients who received endocrine therapy after
breast cancer surgery in our hospital from January 2016 to January 2019 were collected as the research objects . -
pubmed
EVs are released into the extracellular space , in most
human biological fluids and tissues , including
atherosclerotic plaques . -
pubmed
Time to initial
SCC was analyzed using the Kaplan - Meier method , and Cox proportional hazards regression was used to identify predictors of SCC.Among 384
patients enrolled with
MDR - TB , 359 ( 93.5 % ) successfully achieved initial
SCC after a median of 85 days ( interquartile range , 40 - 112 days ) . -
pubmed
From 4464 screened
participants , 557 amyloid - positive , cognitively normal ( Clinical
Dementia Rating of 0 ; aged 60 - 85 years ) participants ( approximately 34 % of originally planned 1650 ) were randomized before the trial sponsor stopped enrollment . -
pubmed
Our results also highlight the value of using the RCS
rat to model sectorial
retinitis pigmentosa , a disease known to predominantly effect the inferior retina . -
pubmed
OBJECTIVE : To assess the role of TE in
HIV infected patients with
NAFLD . -
pubmed
EXCLUSION CRITERIA : pregnancy ;
alcohol intake > = 20g / day and co -
infection with
hepatitis B or C.
Patients underwent abdominal US to diagnose
liver steatosis . -
pubmed
Liver steatosis was diagnosed in 31
patients ( 31.6 % ) and was independently associated with male sex ( PR= 2.18 ) and higher
BMI ( PR=1.08 ) . -
pubmed
Among the 31
patients with
NAFLD , 26 had results for
TE , APRI and FIB4 . -
pubmed
CONCLUSIONS :
NAFLD prevalence in
HIV infected patients is higher than general population . -
pubmed
TE > = 7.1kPa was not able to diagnose significant
fibrosis , but accurately detect a subgroup of patients with high risk for
NASH among
HIV monoinfected individuals with
steatosis . -
pubmed
T cells and
human autoimmune thyroid disease : emerging data show lack of need to invoke suppressor T cell problems . -
pubmed
In
animal models , T cells are able to transfer
autoimmune thyroiditis and T cells have , therefore , long been implicated in the etiology of
human autoimmune thyroid disease (
AITD ) . -
pubmed
Information gained from the study of intrathyroidal T cells and
thyroid antigen - specific T - cell clones has shown that in
patients with
Graves ' disease , mainly
helper T - cell clones have been obtained , whereas in
autoimmune ( Hashimoto ' s ) thyroiditis cytolytic T - cell clones may be predominant . -
pubmed
Recent findings of restricted T - cell receptor V gene use amongst intrathyroidal T cells confirm the primary role of T cells in
human thyroid autoimmune processes leading to
AITD . -
pubmed
When plated at appropriate densities in serum - free media , the
COMMA - D mammary epithelial cell line rapidly reorganizes into multicellular spheres on the basement membrane matrix derived from Engelbreth - Holm - Swarm
murine tumor . -
pubmed
Epithelial respiratory cells from
cystic fibrosis patients do not possess specific
Pseudomonas aeruginosa - adhesive properties . -
pubmed
Nasal
polyp cells in primary culture from
cystic fibrosis (
CF ) and
non - CF patients were compared for the ability to bind
Pseudomonas aeruginosa cells and for the presence of sulphated glycoconjugates at the epithelial cell surface . -
pubmed
Quantitation of
bacterial adhesion , by scanning electronmicroscopy , showed no significant difference between the cells cultured from
CF and non - CF
patients . -
pubmed
The interaction of aggregated
P aeruginosa cells with
polyp cells cultured from both
CF and
non - CF patients appeared to occur by means of this matrix material . -
pubmed
Our findings suggest that chronic colonisation of the airways of
CF patients can not be explained by an increased affinity between the
P. - pubmed
inoculated
P388 leukemia- and
M5076 sarcoma - bearing
mice . -
pubmed
Furthermore ,
KW-2149 remarkably increased the life span of
MMC - resistant
P388 leukemia- and
L1210 leukemia - bearing mice . -
pubmed
KW-2149 and
MMC inhibited the growth of
human tumors inoculated into
nude mice . -
pubmed
The in vitro anticellular spectrum of
KW-2149 against 23
human tumor cell lines was similar to that of
MMC . -
pubmed
The
patient was complaining from
pains , two years after the first operation in relation to lateral
recurrence . -
pubmed
Splenic macrophages from
tumor - bearing , but not normal ,
mice were responsible for this immunosuppression , as revealed by negative and positive selection experiments . -
pubmed
The levels of lipocortin I mRNA expression were markedly increased in peripheral blood cells from
tumor - bearing
mice as compared with those from normal
mice . -
pubmed
Lipocortin I mRNA was strongly induced in splenic mononuclear cells from
tumor - bearing
mice . -
pubmed
Some nonimmune organs such as the heart , submaxillary gland , muscle , and bladder also displayed increased levels of lipocortin I mRNA expression in
tumor - bearing
mice . -
pubmed
Giardia - spontaneously cured
mice were rendered resistant to challenge
infection . -
pubmed
Immune - depressed
mice were more susceptible to
Giardia infection , thus proving the active role of antibodies and cell - mediated immune response in
giardiasis . -
pubmed
The long - term results of four different regimens of
prednisone therapy were compared in 32
children with
steroid sensitive , frequently relapsing idiopathic
nephrotic syndrome with minimal
glomerular lesions on renal biopsy . -
pubmed
In frequently relapsing
patients without
steroid dependency the
relapse free intervals were similar with either intermittent or alternate - day
prednisone therapy ( median 75d ) ; however , they were significantly shorter with short - term
prednisone therapy ( median 33d ) . -
pubmed
This study reports on the frequency of point mutations at these codons , in vivo , in
human myeloid malignancies and in normal subjects . -
pubmed
Impaired natural defence of beige (
Chediak - Higashi syndrome )
mice against tissue - migrating larvae of
Strongyloides ratti and its reconstitution by bone marrow cells . -
pubmed
The susceptibility of C57BL/6 - bgJ / bgJ
mice , which exhibit a
murine counterpart of the
Chediak - Higashi syndrome , to infection with
Strongyloides ratti was examined . -
pubmed
After a primary
infection , the peak of the daily larval output in faeces ( LPG ) of bgJ / bgJ
mice was approximately twice as high as that of their littermate bgJ/+
mice . -
pubmed
The total number of tissue migrating larvae recovered from bgJ / bgJ
mice at 36 h after
infection was also approximately twice as high as that from bgJ/+
mice . -
pubmed
However , after a primary
infection , bgJ / bgJ
mice could completely expel adult worms in the intestine by day 14 . -
pubmed
The higher susceptibility of bgJ / bgJ
mice could be reduced to the level of bgJ/+
mice by bone marrow grafting from bgJ/+
mice 6 weeks prior to
infection . -
pubmed
The severity of
valvular aortic stenosis was assessed by Doppler color flow mapping in 100 consecutive
patients who underwent successful cardiac catheterization within 2 weeks of the Doppler study . -
pubmed
The
aortic stenosis jet was not seen in 39
patients ( Group B ) , and the mean pressure gradient and aortic valve area in these patients were assessed by conventional Doppler echocardiography alone . -
pubmed
The maximal
aortic stenosis jet width also correlated well with the aortic valve area estimated at catheterization in 54
patients ( r = 0.90 ) . -
pubmed
Effects of antihypertensive treatment on the cerebral microvasculature of spontaneously
hypertensive rats . -
pubmed
Experiments were performed in anesthetized 18 - 19 - week - old spontaneously
hypertensive rats ( SHR ) to evaluate the effects of delayed antihypertensive treatment on cerebrovascular function . -
pubmed
Animals were treated for 25 + /- 1 days with an oral antihypertensive regimen consisting of
hydralazine ,
reserpine , and
chlorothiazide , resulting in
normotension within 2 weeks . -
pubmed
Specimens from aganglionic ( constricted ) and ganglionic ( dilated ) gut were obtained from nine
patients with
Hirschsprung ' s disease . -
pubmed
Ten normal subjects and 9
patients affected by
aortic regurgitation were used as controls . -
pubmed
In eighty consecutive
patients who have the
dysplastic nevus syndrome , the concentration of
nevocytic nevi on the relatively sun - protected lateral thoracic area was compared to the concentration on the relatively sun - exposed areas of the anterior and posterior thorax . -
pubmed
These findings are consonant with the hypothesis that sunlight induces
nevocytic nevi in
patients who have the
dysplastic nevus syndrome . -
pubmed
The endolymphatic sacs are described in temporal bone specimens from a 31 - year - old
man with bilateral
Mondini disorder . -
pubmed
A severe
spinal deformity in a
cape buffalo calf (
Syncerus caffer ) similar to " short spine lethal " of Angus
cattle (
Bos taurus ) . -
pubmed
[ Therapy of
liver diseases with
protoporphyrin sodium in
children ] . -
pubmed
Cortical biopsies obtained from 5 young
children with severe
neurobehavioral retardation of unknown etiology have been analyzed using Golgi and EM techniques . -
pubmed
These
mice were also capable of rejecting allogeneic
mouse skin and
rat skin from a
strain ( Buffalo ) unrelated to the thymus donor ; however , they were incapable of rejecting
rat skin from the thymus donor
strain . -
pubmed
Experimental
auto - allergic sialoadenitis in male
rats . -
pubmed
Induced
auto - allergic lesions in the submandibular glands of
rats were studied by immunofluorescence . -
pubmed
In individual
rats , no relationship was found between the presence or absence of serum anti - salivary antibodies and the presence or absence of
salivary auto - allergic lesions . -
pubmed
Egg output of
Graphidium strigosum ( Nematoda ) in low - level prime
infection of
rabbits . -
pubmed
These derivatives had also an improved antimycoplasmal activity ; MIC values were 0.08 microgram / ml against
macrolide - resistant
strains of
Mycoplasma gallisepticum . -
pubmed
As an example of the chemical work done in this study , the analysis of two plants is reported :
Pueraria lobata (
Ge - gen ) , which contains an
isoflavonoid glycoside with
hypotensive effects , with excellent clinical results in the treatment of
hypertension ; and
Anisodus tanguticus , which contains
anisodamine , or
6 - hydroxy hyoscyamine , which proved to be similar in effect to
atropine but milder in action on the CNS . -
pubmed
Left ventricular thrombi in
children with
dilated cardiomyopathy . -
pubmed
To define the nature and course of left ventricular ( LV )
thrombi in pediatric patients , the charts and echocardiographic records of 32 pediatric
patients with
dilated cardiomyopathy from 1986 to 1991 were retrospectively reviewed . -
pubmed
Five
patients who were identified according to echocardiographic evidence of LV
thrombi fulfilled the criteria of
dilated cardiomyopathy . -
pubmed
Systemic embolization occurred in three
patients with LV
thrombi who invariably died despite anticoagulant treatment . -
pubmed
Although it was not statistically significant ,
patients with LV
thrombi tended to have a lower ejection fraction compared to
patients without LV
thrombi . -
pubmed
The morphology of LV
thrombi in
patients with systemic embolization showed nonprotruding features . -
pubmed
Thus ,
children with
dilated cardiomyopathy are at risk of developing LV
thrombi and systemic embolization . -
pubmed
Although it was not possible to identify the risk factors , the risk of developing LV
thrombi and systemic embolization may be higher in
patients with lower ejection fraction of the left ventricle . -
pubmed
Thrombolytic therapy was administered to a 64 - year - old
man with an acute
anterolateral myocardial infarction who had received cardiopulmonary resuscitation ( CPR ) for 24 minutes . -
pubmed
At the time of thrombolytic therapy , the
patient was alert and without clinical or radiographic evidence of
injury . -
pubmed
The
patient developed a retroperitoneal
hematoma related to femoral line placement , as well as subcutaneous
bruising of the anterior chest wall ; both were self - limited . -
pubmed
The use of thrombolytic therapy for
patients with acute
myocardial infarction who have received CPR is reviewed . -
pubmed
In the absence of clinical or radiographic evidence of
trauma from CPR ,
patients with acute
myocardial infarction should not be excluded from receiving thrombolytic therapy solely because of having had CPR or the duration of CPR . -
pubmed
Scid
mice heterotopically transplanted with gut from a congenic , immunocompetent donor developed clinical and histological signs of
inflammatory bowel disease (
IBD ) . -
pubmed
Changed blood rheology in
patients with
idiopathic dilated cardiomyopathy . -
pubmed
Rheologic properties of blood were studied in 8
patients with
dilated cardiomyopathy (
DCM ) and in 10 healthy subjects . -
pubmed
The measured hemorheologic abnormalities may contribute to the previously reported reduction of coronary blood flow reserve in
DCM patients and to myocardial microcirculatory disturbances , which have been suggested as a cause for
DCM . -
pubmed
Fine needle aspiration ( FNA ) cytology of lipid - secreting
carcinoma of the breast was performed on a 43 - year - old
woman who was admitted with a left
breast tumor . -
pubmed
Pathogenesis of
tuberculosis : interaction of
Mycobacterium tuberculosis with macrophages . -
pubmed
Thoria - labelled
murine and
human macrophages were infected with a virulent (
H37Rv ) or avirulent ( H37Ra )
strain of
M. - pubmed
Only viable
H37Rv showed a significant increase in bacterial counts during the course of
infection . -
pubmed
Thus , both of the attenuated
strains we examined differed from the virulent
strain H37Rv in their abilities to replicate successfully within macrophages , but each diverged from
H37Rv at a different point in the process . -
pubmed
Viable tubercle bacilli
H37Rv and
H37Ra had the capacity to escape from fused vesicles as the
infection progressed ;
BCG did not . -
pubmed
Samples from sixty - two
periodontal pockets were collected at pocket depths of over 4 mm in twenty - one
periodontitis patients aged 43 to 75 years . -
pubmed
However , clinical
strains of
P. - pubmed
Of all the 487
patients 32 % received thrombolytic treatment ; i.e 36 % of those with definite or suspected
myocardial infarction on admission . -
pubmed
A 59 - year - old
man with
mouth pain . -
pubmed
MATERIALS AND METHODS : Fourteen
breast cancers were examined in 13
women with MRI , ultrasonography and mammography . -
pubmed
DNA sequences that cross - hybridize with K139 phage DNA are present in all
strains of
V. - pubmed
This results suggests that O139
strains arose in part by horizontal gene transfer of the O139 antigen genes into an
El Tor O1 strain that harboured a K139 prophage . -
pubmed
BACKGROUND AND PURPOSE :
Hematoma volume is an important determinant of outcome and predictor of
clinical deterioration in
patients with
intracerebral hemorrhage . -
pubmed
METHODS : TCD was performed an average of 1.1 days ( range , 0 to 3 days ) after onset in 30
patients with supratentorial
intracerebral hemorrhage . -
pubmed
Compared with
patients with small
hemorrhages , those with large
hemorrhages ( & gt ; or = 25 mL , n = 10 ) had significantly higher ipsilateral pulsatility indexes ( 1.72 versus 1.13 , P & lt ; .0001 ) and higher ratios of ipsilateral - to - contralateral pulsatility ( 1.29 versus 1.06 , P = .001 ) . -
pubmed
The ratio of ipsilateral - to - contralateral mean velocity was similarly reduced in
patients with large versus small
hemorrhages ( 0.87 versus 1.06 , P = .01 ) , but this effect was less pronounced . -
pubmed
In a prospective , randomised , controlled trial of 92
patients with full - thickness pressure
ulcers , the efficacy of an alginate
wound dressing was compared to that of an established local treatment with dextranomer paste . -
pubmed
During treatment , a minimal 40 % reduction in
wound area was obtained in 74 % of the
patients in the alginate group and in 42 % of those in the
dextranomer group . -
pubmed
On this evidence , an attempt is made to interpret earlier discovered changes in the immunobiochemical status of these
patients and plausible mechanisms of progressive arterial
hypertension are hypothesized . -
pubmed
Patients with
intracranial aneurysm either present catastrophically with
rupture of the
aneurysm have
aneurysms that are incidentally discovered . -
pubmed
On the other hand , the surgical or endovascular mortality following treatment of an unruptured
aneurysm is minimal , with good
patient neurological outcome . -
pubmed
We performed LC on an emergency basis as soon as the diagnosis was made on all
patients presenting with
acute cholecystitis from January 1994 to December 1995 . -
pubmed
Patients with an operative delay of 96 hours or less from the onset of acute
cholecystitis had a conversion rate of 23 % , whereas a delay of more than 96 hours was associated with a conversion rate of 47 % ( p = 0.022 ) . -
pubmed
Patients over 65 years of age , with a history of
biliary disease , a nonpalpable gallbladder , WBC count over 13,000 / cc , and acute gangrenous
cholecystitis were independently associated with a high LC conversion rate ; male
patients , finding large
bile stones , serum
bilirubin over 0.8 mg / dl , and WBC count over 13,000 / cc were independently associated with a high complication rate following laparoscopic surgery with or without conversion . -
pubmed
Assessment of pretransplantation warm
ischemia time by
phosphorus-31 magnetic resonance spectroscopy in
pig kidneys . -
pubmed
Before the onset of
colitis , 15
horses had received antibiotics , 11 had undergone general anaesthesia and various surgical procedures , and 10 had been treated with non - steroidal anti - inflammatory drugs . -
pubmed
The
horses had acute onset , profuse
watery diarrhoea , profound
depression , mild to moderate
abdominal pain , reduced
intestinal borborygmi ,
tachycardia ,
dehydration and
endotoxic shock . -
pubmed
The aetiology of the
colitis could not be determined , but the clinicopathological features resembled those of
colitis attributed to an intestinal overgrowth of
Clostridium perfringens type A. -
pubmed
PURPOSE : The development of objective criteria for selecting
patients for seminal vesicle irradiation on radical radiotherapy for
prostate cancer will be important for successful planning of 3D conformal radiotherapy . -
pubmed
CONCLUSION : Prospective use of the objective criteria will be useful in the selection of
patients for seminal vesicle involvement and should be an integral part in 3D conformal radiotherapy of
prostate cancer . -
pubmed
We studied the relationship between genetic
hypertension and
insulin resistance in SHRSP and Wistar Kyoto
rats ( WKY ) as a control . -
pubmed
We report a case of
pseudomembranous necrotizing bronchial aspergillosis in a
patient with
acute myelocytic leukaemia who died of massive
haemoptysis . -
pubmed
A 47 year old
man with
chronic hepatitis C was treated with
interferon alfa , 3 million units three times a week , and developed widespread
plaque psoriasis within weeks of starting
interferon therapy . -
pubmed
OBJECTIVE : To investigate the occurrence of combined central and peripheral
demyelination in
CIDP patients and to correlate visual evoked potential ( VEP ) abnormalities with CNS
demyelinating lesions , observed on brain magnetic resonance imaging , and antibodies against
glycolipids . -
pubmed
METHODS : Nerve conduction studies , brain MRI and antibodies against
glycolipids were prospectively studied in 17
patients who fulfilled the diagnostic criteria proposed for
CIDP ( Cornblath DR , Asbury AK , Albers JW , Feasby TE , Hahn AF , McLeod JG , Mendell JR , Parry GJ , Pollard JD , Thomas PK . -
pubmed
CONCLUSION : This study confirmed the high frequency of abnormal VEPs in
CIDP patients , and found that they are poorly correlated with
CNS demyelinating lesions and antibodies against
glycolipids . -
pubmed
The
VEP abnormalities of these
patients may be explained by the susceptibility to immune - mediated damage of both the peripheral nervous system and the optic nerve . -
pubmed
To evaluate the presence of
autonomic neuropathy in childhood
uremia , cardiovascular autonomic reflexes were examined in
children with
chronic renal failure . -
pubmed
Cardiovascular autonomic reflexes of 10
uremic patients on chronic dialysis and 10 transplanted
patients were compared to assess the effect of transplantation on
autonomic neuropathy . -
pubmed
Of the 10
uremic children , 4 showed early involvement and 2 had definite involvement of
autonomic neuropathy . -
pubmed
Only 1 of the 10 transplanted
patients showed early signs of
autonomic neuropathy . -
pubmed
In conclusion ,
cardiovascular autonomic neuropathy is not rare in
children and
adolescents and young adults with
chronic renal failure . -
pubmed
In contrast , the prevalence is very low in transplanted
patients with similar
uremic precedents . -
pubmed
Antioxidant and free radical scavenging effects of the
tannins of
Terminalia catappa L. Reactive
oxygen species ( ROS ) react with biological molecules and destroy the structure of cells and eventually cause free radical - induced disease such as
inflammation and
cancer . -
pubmed
ABT-770 and other MMPIs , plus several metabolites of each , were assayed for their ability to induce
phospholipidosis in primary cultured
rat and
human hepatocytes . -
pubmed
At 24 and 48 hr , none of the parent compounds induced
phospholipidosis in vitro in
rat or
human hepatocytes . -
pubmed
The
amine metabolite of another MMPI ,
ABT-518 (
[ S -( R * , R *)]- N -[ 1 -( 2,2 - dimethyl-1,3 - dioxol-4 - yl )- 2 -[[ 4 -[ 4 -( trifluoromethoxy )- phenoxy ] phenyl ] sulfonyl ] ethyl ]- N - hydroxyformamide ) , produced little
phospholipidosis in
rat and
human hepatocytes even at concentrations up to 100 microM. -
pubmed
The presence or absence of
phospholipidosis in the in vitro assay correlated well with ultrastructural findings and drug accumulation in
rat tissues . -
pubmed
Urinary tract infections and a multidrug - resistant
Escherichia coli clonal group . -
pubmed
Efficacy and tolerance of a scalp - cooling system for prevention of
hair loss and the experience of
breast cancer patients treated by adjuvant chemotherapy . -
pubmed
Women accepting the scalp - cooling system were compared for
alopecia both against those who refused and against a " reference " group of 109
patients similarly treated but without being offered a scalp - cooling system . -
pubmed
Hair loss in the 105 study
patients was evaluated by nurses using World Health Organization ( WHO ) criteria at each cycle of chemotherapy . -
pubmed
Tolerance was generally good and no scalp
metastasis was observed among the 77 accepting
patients followed up . -
pubmed
Folate deficiency sensitizes
mice to dopaminergic
neurodegeneration and
motor dysfunction caused by the neurotoxin
1 - methyl-4 - phenyl-1,2,3,6 - tetrahydropyridine (
MPTP ) . -
pubmed
A 52 year old
man developed a
supranuclear gaze palsy and
opsoclonus after
Diazinon poisoning . -
pubmed
[ Contribution of electroencephalography to the study of unilateral
cerebral atrophy of
children ; correlations of pneumoencephalography and electroencephalography ] . -
pubmed
Striatal DAT uptakes were measured in 12 drug - nai;ve
schizophrenic patients and 12 age- and sex - matched healthy
volunteers . -
pubmed
The decreased right uptake and increased left uptake in the striatum might lead to the lack of right - left asymmetry in neuroleptic - nai;ve
schizophrenia patients , confirming that the disorder could be due to a disruption in brain lateralization . -
pubmed
This is the first report on the use TRODAT to evaluate the DAT density in
schizophrenia patients and shows lack of asymmetry in striatal uptake of
TRODAT in
schizophrenics . -
pubmed
The findings also suggest that TRODAT SPECT may be a useful technique to measure
dopamine transmission in the
human brain and for understanding the pathophysiology of
neuropsychiatric disorders . -
pubmed
Contrary to our expectations , we found that most
patients presented with either an early onset
neuropathy with
signs and symptoms prior to the onset of walking or a late onset
neuropathy with
signs and symptoms at around age 40 years . -
pubmed
Human gnathostomiasis : clinical study and report of a case . -
pubmed
Using a
strain of
Staphylococcus aureus ATCC 6538P as the test organism ,
enrofloxacin at concentrations ranging from 3.2 to 12.8 microg ml(-1 ) could be measured in injection . -
pubmed
Whilst disorders of short , medium and very long chain acyl dehydrogenases are known , there is no known disorder of
LCAD deficiency in
humans . -
pubmed
Experimental
LCAD deficiency in
mice shows an
acyl - carnitine profile with prominent elevations of
unsaturated fatty acid metabolites C14:1 and C14:2 [ Hum . -
pubmed
A
child with
autism whose
acyl - carnitine profile also shows these abnormalities is presented , and it is hypothesized that the child may have
LCAD deficiency . -
pubmed
METHODS : Forty - one anesthetized male
mice were subject to
thoracic aortic occlusion ( 11 minutes ) through a cervical mediastinotomy followed by 48 hours of reperfusion ( TAR ) under normothermic conditions . -
pubmed
PJ34 - treated
mice ( PJ , n = 12 ) were given 10 mg / kg
PJ34 intraperitoneally 1 hour before
ischemia and 1 hour after unclamping . -
pubmed
Blinded observers rated
murine neurologic status after TAR by using an established
rodent paralysis scoring system . -
pubmed
RESULTS : Immediately after TAR , UN and PJ
mice had severe
neurologic dysfunction ( PS = 5.8 + /- 0.1 and 4.6 + /- 0.6 , respectively ; P & gt ; .05 ) , which was significantly worse than the KO
mice ( PS = 1.0 + /- 0.7 , P & lt ; .001 ) . -
pubmed
After 6 , 24 , and 48 hours KO
mice had no discernable
neurologic injury ( PS = 0 ) . -
pubmed
UN
mice did not improve their PS , and Sham
mice showed no
neurologic abnormality at any time during these experiments . -
pubmed
MOTIVATION : Although the outbreak of the severe
acute respiratory syndrome (
SARS ) is currently over , it is expected that it will return to attack
human beings . -
pubmed
This excess risk can be attributed to high rates of
chronic hepatitis B viral ( HBV ) infection and low rates of
HBV vaccination among Asian immigrants . -
pubmed
Iron status and clinical outcome in
patients with
coronary artery disease after coronary stenting . -
pubmed
We conducted this study to investigate whether there is an association between body
iron status and clinical outcome in
patients with
coronary artery disease after coronary stenting . -
pubmed
METHODS AND RESULTS : The study included 664
patients with
coronary artery disease who underwent coronary stent implantation . -
pubmed
CONCLUSIONS : Our study showed no association between
iron status and the incidence of major adverse cardiac events or angiographic
coronary restenosis in
patients with
coronary artery disease after coronary stenting . -
pubmed
Patients with moderate to severe
chronic hepatitis and active
HBV replication should be managed according to
HBeAg status and presence of coinfecting virus(es ) (
HDV ,
HCV ,
HIV ) . -
pubmed
Malaria infection in
HIV - seropositive and
HIV - seronegative individuals in Jos - Nigeria . -
pubmed
Helicobacter pylori eradication in
peptic dyspepsia . -
pubmed
In addition , arthroscopy is a useful adjunct during surgical treatment of
patients with certain juxta - articular benign
bone tumors . -
pubmed
The effect of
hyaluronic acid and phospholipid based lubricants on friction within a
human cartilage damage model . -
pubmed
Levels of start - up friction were determined using an
osteoarthritis ( OA ) damaged
human cartilage model set within a specially designed friction rig . -
pubmed
Institution - specific protocols which reflect current guidelines may increase the number of ST - segment elevation
myocardial infarction patients who receive timely reperfusion . -
pubmed
BACKGROUND : The management of
patients who are receiving
warfarin therapy and have musculoskeletal problems that require treatment with a nonsteroidal antiinflammatory drug ( NSAID ) is problematic because NSAID use may increase the risk for
bleeding . -
pubmed
METHODS : We performed a randomized , controlled , crossover trial to assess the effect on INR of
celecoxib versus
codeine ( control treatment ) in 15
patients who were receiving
warfarin therapy and required analgesic treatment for
osteoarthritis . -
pubmed
UNLABELLED : The first herpes virus to be described was types 1 and 2 , whose denomination is
herpes simplex 1 and 2 or
HSV-1 and
HSV-2 . -
pubmed
METHODOLOGY : We evaluated 38
patients with
Bell ' s palsy submitted to anamnesis , clinical and ENT examination and saliva sampling for viral DNA detection by PCR technique . -
pubmed
CONCLUSION : The end result was that the presence of
HSV-1 in the saliva of
patients with
Bell ' s palsy indicating that the viral reactivation can be the etiology of this disease . -
pubmed
A 43 - year - old
woman with a history of
cocaine abuse presented with decreased mental responsiveness and
cyanosis of the extremities several hours after repeated use of "
crack " cocaine . -
pubmed
One
patient died as a direct consequence of the initial
SAH . -
pubmed
The technique may be considered as an alternative therapeutic option in selected
patients with ruptured
VBA -
DAs unsuitable for internal trapping of the parent artery . -
pubmed
OBJECTIVE : To relate morphology of new bone formation to outcome after tibial lengthening performed in
patients with
achondroplasia . -
pubmed
MATERIAL AND METHODS : A retrospective analysis of 60 tibial segments in 30
achondroplasia patients was performed . -
pubmed
Nonetheless , some of the adaptations in the
animals on these unique islands may have bearing on my hypotheses related to the incidence and pathogenesis of
otitis media in
humans . -
pubmed
Effects of chronic exposure to
DDT and
TCDD on disease activity in
murine systemic lupus erythematosus . -
pubmed
This study examined the effects of chronic exposure to xenoestrogens --
o , p '- dichlorodiphenyltrichloroethane (
DDT ) and
2,3,7,8 - tetrachlorodibenzo - p - dioxin (
TCDD ) on disease activity in the New Zealand Black / New Zealand White F1 hybrid ( B / W )
mouse model of
SLE . -
pubmed
Taken together ,
DDT exposure appeared to accelerate the development of
albuminuria in lupus - prone
mice . -
pubmed
TCDD was immunosuppressive to
murine SLE . -
pubmed
Trichophyton rubrum is the most common agent of
dermatophytosis , a disease that affects millions of individuals worldwide . -
pubmed
Effect of inhomogeneous static magnetic field on dental
pain in
humans . -
pubmed
Herein , we describe the placement of a novel , self - retaining , active - fixation coronary
sinus lead -- the Attain StarFix Model 4195 OTW Lead -- in an elderly
heart - failure patient , via the femoral approach . -
pubmed
Following
spinal cord injury (
SCI ) in
mammals , there is only limited repair and consequently only moderate recovery . -
pubmed
However , the antihyperglycemic effect of the
n - butanol fraction was not observed in
diabetic rats . -
pubmed
AIMS : To evaluate the prevalence and characteristics of different neurological and psychiatric presentations in
patients admitted to hospital with
systemic lupus erythematosus (
SLE ) . -
pubmed
MATERIALS AND METHODS : In this retrospective hospital - based study , we examined the medical records of
patients with
SLE who were referred to the hospitals affiliated to Shiraz University of Medical Sciences from 1995 to 2005 . -
pubmed
RESULTS : Of the 407 study
patients , 11.3 % had
neuropsychiatric complications . -
pubmed
Acid sphingomyelinase deficiency attenuates
bleomycin - induced
lung inflammation and
fibrosis in
mice . -
pubmed
[ Prevalence of
HPV 16 , 18 , 45 and 31 in women with
cervical lesions ] . -
pubmed
Multiple
infections occurred in 15 % of the cases and
infections with other
HPV types were detected in 14 % of the sample . -
pubmed
CONCLUSIONS :
HPV 16 and 18
infections do not always occur as a single
infection , and may be associated with other
HPV types on different occasions . -
pubmed
We describe a 64 - year - old
man who presented with progressive
dysphagia and
weight loss . -
pubmed
BACKGROUND AND PURPOSE : The aim of the study was to evaluate the influence of visual control on parameters of postural stability among
patients with
Parkinson disease (
PD ) in comparison with control subjects . -
pubmed
MATERIAL AND METHODS : Fifty
patients diagnosed with
idiopathic PD and 50 control
subjects without features of
central nervous system injury were selected for the study . -
pubmed
CONCLUSIONS : Visual control significantly affects the parameters of postural stability in
PD patients . -
pubmed
BACKGROUND :
Streptococcus pneumoniae ,
Moraxella catarrhalis , and nontypeable
Haemophilus influenzae is associated with
otitis media (
OM ) . -
pubmed
Development of an effective vaccine against
tuberculosis hinges on an improved understanding of the
human immune response to
Mycobacterium tuberculosis (
Mtb ) . -
pubmed
OBJECTIVE :
Patients with
primary hyperparathyroidism (
pHPT ) are at increased risk of cardiovascular mortality . -
pubmed
METHODS : Twenty - four
patients with mild
pHPT ( age 56 + - 10 years , blood pressure 136/85 mmHg , serum
calcium 2.55 - 3.00 mmol / L ) and 48 control subjects individually matched with cases by age , sex and blood pressure underwent aortic ( carotid - femoral ) and upper - limb ( carotid - radial )
pulse wave velocity ( PWV ) determination by applanation tonometry in a case - control study . -
pubmed
Subjects with
renal disease ,
diabetes , treated
hypertension or overt
cardiovascular disease were excluded from the study . -
pubmed
Seventeen of the
patients with
pHPT were re - examined 4 weeks after surgical parathyroidectomy . -
pubmed
Anti -
diabetic effect of
pyroglutamic acid in
type 2 diabetic Goto - Kakizaki
rats and KK - Ay
mice . -
pubmed
Evolutionary and protein structural analyses can provide functional insights into genes implicated in
human psychiatric diseases . -
pubmed
The effects of high custom made shoes on gait characteristics and
patient satisfaction in
hemiplegic gait . -
pubmed
OBJECTIVE : To determine the effects of a temporary high custom made orthopaedic shoe on functional mobility , walking speed , and gait characteristics in
hemiplegic stroke patients . -
pubmed
PARTICIPANTS : Nineteen
stroke patients ( 12
males ; mean age 55 years ( standard deviation ( SD ) 10 years ) ; mean time post onset 3.6 months ( SD 1.4 months ) ) with a
spastic paresis of the lower extremity . -
pubmed
[ Update on
HPV - induced
oropharyngeal cancer ] . -
pubmed
Moreover , the present protocol is appropriate for the isolation of microglia from autopsy samples irrespective of the neurological state of the brain or specific brain regions and ( with minor modification ) could be even used for the isolation of microglia from
human glioma tissue . -
pubmed
When
patients die after chiropractic or surgical interventions of the cervical spine , pathologists tasked with the autopsy are frequently overwhelmed by the complicated anatomy , laborious dissections , complex operative procedures and surgical hardware , and the necessity to differentiate artifacts from
trauma and disease . -
pubmed
OBJECTIVE : To describe 2
patients presenting with
idiopathic tinnitus concomitant with eye closure . -
pubmed
PATIENTS : Two
patients presented with intermittent
tinnitus synchronous with eye closing or blinking . -
pubmed
Neither
patient had
facial nerve disease or
myoclonus . -
pubmed
CONCLUSION : These are the rare 2 reported
patients presenting with idiopathic
muscular tinnitus concomitant with eye closure . -
pubmed
We suggest evaluation of compliance change in impedance audiometry to be a key examination in
patients with stapedial
muscular tinnitus concomitant with eye closure . -
pubmed
METHODS : A sample of 479
individuals aged 50 years or above ( average 66 + - 9.1 years ) , followed in primary care , with no history of
brain disorder were asked two questions concerning SLC , fulfilled a
depression scale and undertook a battery of cognitive tests . -
pubmed
Perioperative considerations in
patients with
Gitelman syndrome : a case series . -
pubmed
STUDY OBJECTIVE : To determine the perioperative considerations for low - risk and high - risk surgery in
patients with
Gitelman syndrome . -
pubmed
PATIENTS : 42
patients with
Gitelman syndrome . -
pubmed
MEASUREMENTS : Of the 42
patients with
Gitelman syndrome , 5 underwent procedures requiring anesthesia : mastectomy , spinal fusion , thyroidectomy , tonsillectomy , and bronchoscopy . -
pubmed
MAIN RESULTS : No acute
electrolyte abnormalities or
postoperative complications occurred with these procedures in
patients with
Gitelman syndrome . -
pubmed
Bevacizumab versus
ranibizumab in the treatment of exudative age - related
macular degeneration : a retrospective study of 58
patients . -
pubmed
PATIENTS AND METHODS : Retrospective case - controlled series of 30
patients treated with intravitreal
bevacizumab and 28
patients treated with intravitreal
ranibizumab for
exudative AMD . -
pubmed
Total arterial off - pump coronary artery bypass in a
patient with
situs inversus and
dextrocardia . -
pubmed
Genetic alterations and deregulation of the miRNA biogenesis pathway components have been reported in
human tumors . -
pubmed
This study investigated the effects of steady - state
liraglutide 1.8 mg versus placebo on postprandial plasma lipid concentrations after 3 weeks of treatment in
patients with
type 2 diabetes mellitus (
T2DM ) . -
pubmed
METHODS : In a cross - over trial ,
patients with
T2DM ( n = 20 , 18 - 75 years ,
BMI 18.5 - 40 kg / m2 ) were randomized to once - daily subcutaneous liraglutide ( weekly dose escalation from 0.6 to 1.8 mg ) and placebo . -
pubmed
Serum
copper ,
zinc and
selenium levels in Tunisian
patients with
Parkinson ' s disease . -
pubmed
METHODS : A serum level of 3 trace elements (
Cu ,
Zn and
Se ) was investigated in 48
patients with
PD and 36 matched controls using plasma atomic absorption spectrometry . -
pubmed
We compared these parameters in
PD patients with controls , and we also compared the variations within the
PD group according to age , illness duration , stage of the disease and
levodopa intake . -
pubmed
RESULTS :
Patients with
PD had significantly lower
Cu levels compared to controls . -
pubmed
The mean
Zn and
Se levels in
PD patients did not differ significantly from those of controls . -
pubmed
Lymph node
metastasis in
gastric cardiac adenocarcinoma in male
patients . -
pubmed
METHODS : We retrospective reviewed a total of 146 male and female
patients with
gastric cardiac adenocarcinoma who had undergone curative gastrectomy with lymphadenectomy in the Department of Surgery , Xin Hua Hospital and Rui Jin Hospital of Shanghai Jiaotong University Medical School between November 2001 and May 2012 . -
pubmed
RESULTS : The rate of lymph node
metastases in male
patients with
gastric cardiac adenocarcinoma was 72.1 % . -
pubmed
Univariate analysis showed an obvious correlation between lymph node
metastases and
tumor size , gross appearance , differentiation , pathological
tumor depth , and lymphatic invasion in male
patients . -
pubmed
Multivariate logistic regression analysis revealed that
tumor differentiation and pathological
tumor depth were the independent risk factors for lymph node
metastases in male
patients . -
pubmed
There was an obvious relationship between lymph node
metastases and
tumor size , gross appearance , differentiation , pathological
tumor depth , lymphatic invasion at pN1 and pN2 , and
nerve invasion at pN3 in male
patients . -
pubmed
There were no significant differences in clinicopathological features or lymph node
metastases between female and male
patients . -
pubmed
CONCLUSION :
Tumor differentiation and
tumor depth were risk factors for lymph node
metastases in male
patients with
gastric cardiac adenocarcinoma and should be considered when choosing surgery . -
pubmed
Quantifying vascular heterogeneity using microbubble disruption - replenishment kinetics in
patients with
renal cell cancer . -
pubmed
PURPOSE : The purposes of this study were to establish the physiological interpretation of the shape parameter of the dynamic contrast - enhanced ultrasound ( DCE - US ) lognormal perfusion model and to evaluate the clinical significance of the parameter in a sample of
patients undergoing antiangiogenic therapy for
metastatic renal cell carcinoma (
mRCC ) . -
pubmed
Dynamic contrast - enhanced ultrasound data were obtained from 31 consenting
patients with
mRCC being treated with antiangiogenic therapy . -
pubmed
A more abnormal flow distribution at baseline predicts for poorer outcome for
patients treated with antiangiogenic therapy for
metastatic renal cell cancer . -
pubmed
METHODS :
Patients diagnosed with a
pituitary adenoma and treated with two or more courses of radiation treatment ( RT ) to the sella were retrospectively analyzed for : initial diagnosis , including histological type and functional status ; RT modality , technique , dose , and fractionation ; treatment with surgery , endocrine agents , and chemotherapy ;
toxicity of RT including radiation - induced
optic neuropathy ,
radionecrosis , and radiation - induced
neoplasms ; and outcomes including local control , distant
metastasis , biochemical control of functional
tumors , and vital status at last follow - up . -
pubmed
RESULTS : We identified 15
patients with non - functioning
pituitary adenoma ( n = 6 ) ,
Cushing ' s disease (
CD ) ( n = 5 ) ,
acromegaly ( n = 3 ) , and
prolactinoma ( n = 1 ) . -
pubmed
Radiation - induced
optic neuropathy (
RION ) was observed in 2 ( 13.3 % )
patients , 6 months and 14 years after re - irradiation ; the 5 - year rate of
RION was 9 % . -
pubmed
Biochemical remission occurred in one of three
patients with
CD . -
pubmed
Four
patients ( 27 % ) ultimately developed
pituitary carcinoma . -
pubmed
Antioxidant effects of
maslinic acid in livers , hearts and kidneys of
streptozotocin - induced
diabetic rats : effects on kidney function . -
pubmed
We , therefore , investigated the effects of 5 - week MA treatment of
streptozotocin (
STZ)-induced
diabetic rats on anti - oxidative status of cardiac , hepatic and renal tissues as well as on kidney function . -
pubmed
In the United Kingdom , European badgers
Meles meles are a protected species and an important wildlife reservoir of bovine
tuberculosis . -
pubmed
Methamphetamine (
Meth ) can evoke extreme
hyperthermia , which correlates with
neurotoxicity and
death in laboratory animals and
humans . -
pubmed
Modern
soya formulas are used in
allergy / intolerance to
cows ' milk - based formulas ( CMF ) ,
post - infectious diarrhoea ,
lactose intolerance and
galactosaemia , as a vegan
human milk ( HM ) substitute , etc . -
pubmed
Feasibility study of personalized peptide vaccination for metastatic recurrent triple - negative
breast cancer patients . -
pubmed
Herein we conducted a phase II study of PPV for metastatic recurrent
breast cancer patients to investigate the feasibility of PPV for mrTNBC . -
pubmed
METHODS : Seventy - nine
patients with metastatic recurrent
breast cancer who had
metastases and had failed standard chemotherapy and/or hormonal therapy were enrolled . -
pubmed
In this study
bipolar RF was assessed in the 20
subjects , who are in treatment of periorbital rhytides and it was proved that it can successfully treat the periorbital rhytides . -
pubmed
Cytotoxic activity of the methanolic extract of
Turnera diffusa Willd on
breast cancer cells . -
pubmed
The aim of the present study was to evaluate the possible
cytotoxic effect of extracts and organic fractions of this plant on five
tumor cell lines (
SiHa ,
C-33 ,
Hep G2 ,
MDA - MB-231 , and
T-47D ) and normal
human fibroblasts . -
pubmed
This is the first report of a
cytotoxic effect by
T. - pubmed
A preliminary observation of
weight loss following left gastric artery embolization in
humans . -
pubmed
However ,
weight loss after LGA embolization in
humans has not been previously established . -
pubmed
The aim of this study was to evaluate postprocedural
weight loss in
patients following LGA embolization . -
pubmed
SUBJECTS / METHODS : A retrospective analysis of the medical records of
patients who underwent LGA embolization for
upper gastrointestinal ( GI ) bleeding was performed . -
pubmed
Postprocedural
weight loss in this group was compared to a control group of
patients who had undergone embolization of other arteries for upper
GI bleeding . -
pubmed
CONCLUSIONS : The current data suggest that
body weight in
humans may be modulated via LGA embolization . -
pubmed
A first - in -
human clinical trial of ultrasmall inorganic hybrid nanoparticles , " C dots " ( Cornell dots ) , in
patients with
metastatic melanoma is described for the imaging of
cancer . -
pubmed
( 124 ) I - cRGDY - PEG - C dot particles are inherently fluorescent , containing the dye ,
Cy5 , so they may be used as hybrid PET - optical imaging agents for lesion detection ,
cancer staging , and treatment management in
humans . -
pubmed
Coupled with preferential uptake and localization of the probe at sites of disease , these first - in -
human results suggest safe use of these particles in
human cancer diagnostics . -
pubmed
Parathyroid
carcinoma with
intracranial metastasis at diagnosis in a
patient with uncontrolled
hypercalcemia . -
pubmed
We report a case of metastatic parathyroid
carcinoma with two intracranial metastatic foci ( in the left frontal lobe and left cerebellar hemisphere ) identified at the time of the primary
tumor diagnosis in a
patient who presented with symptomatic
hypercalcemia . -
pubmed
Significant work has been done towards identifying the health - beneficial effects of the
grape antioxidant
resveratrol in a variety of bioassay- and disease- models , with much research being focused on its possible application to
cancer management . -
pubmed
Dysphagia ,
hoarseness , and globus in a postoperative
patient . -
pubmed
We present a case of a single
patient who presented to a tertiary care center after an elective outpatient procedure with
postoperative sore throat ,
hoarseness , and
dysphagia . -
pubmed
BACKGROUND :
Coagulopathy is a major issue in
children undergoing high - risk pediatric cardiac surgery . -
pubmed
This study aims to study the benefits
tranexamic acid in controlling
postoperative bleeding in pediatric cardiac surgical
patients . -
pubmed
Intraperitoneal administration of
butyrate prevents the severity of
acetic acid colitis in
rats . -
pubmed
The current study aimed at exploring and comparing the potential of intraperitoneally , intrarectally , and orally administered
butyrate against
acetic acid ( AA)-induced
UC in
rats . -
pubmed
We herein report a 35 - year - old
woman with
cardiac diffuse large B - cell lymphoma (
DLBCL ) with
breast infiltration . -
pubmed
The
patient was admitted to our hospital based on an initial presentation with
dyspnea on exertion ,
chest pain , and a hard mass of the left breast . -
pubmed
The increase in
body weight ( Deltabody weight ) in
patients without
knee problems was 13.5 kg ( 95 % CI 12.9 - 14.2 , range 3 - 38 ) . -
pubmed
Patients with incident
knee pain experienced a Deltabody weight of 16.8 kg ( 95 % CI 13.9 - 19.4 , range 6 - 35 ) . -
pubmed
The compounds were active against 9 out of 12 tested microorganisms including a resistant
strain ;
vancomycin - resistant entrococci (
VRE ) ,
Escherichia coli ,
Staphylococcus aureus and
Candida albicans . -
pubmed
MATERIALS AND METHODS : This review delves further into the current literature to discuss a possible algorithm for managing the risk of
stress incontinence after
pelvic organ prolapse repair and examines the support in the literature for the following treatment methods : ( 1 ) anti - incontinence surgery for all
women undergoing
pelvic organ prolapse repair , ( 2 ) anti - incontinence surgery for no women undergoing
pelvic organ prolapse repair , and ( 3 ) anti - incontinence surgery in select women undergoing
pelvic organ prolapse repair . -
pubmed
OBJECTIVES : The classical presentation of
giant cell arteritis (
GCA ) includes the new onset of
headache ,
scalp tenderness ,
facial pain or
jaw claudication in an older
patient . -
pubmed
Results after En Bloc Lateral Wall Decompression Surgery with Orbital Fat Resection in 111
Patients with
Graves ' Orbitopathy . -
pubmed
A retrospective , noncomparative case series study from 1999 to 2011 ( chart review ) in
Graves ' orbitopathy (
GO )
patients . -
pubmed
Mean
exophthalmos reduction was 3.05 mm and preoperative orbital pressure sensation resolved or improved in all
patients . -
pubmed
Preoperative
diplopia improved in 10
patients ( 9.0 % ) but worsened in 5
patients ( 4.5 % ) , necessitating surgical correction in 3
patients . -
pubmed
There were no significant complications ; however , one
patient had slight hollowing of the temporalis muscle around the
scar that did not necessitate revision , and another
patient with a circumscribed retraction of the
scar itself underwent surgical correction . -
pubmed
The study confirms the efficiency of en bloc lateral wall decompression in
GO in a large series of
patients , highlighting the low risk of disturbance of binocular functions and of cosmetic blemish in the temporal midface region . -
pubmed
Pharmacokinetic and Pharmacodynamic Properties of Oral
Voriconazole in
Patients with Invasive
Fungal Infections . -
pubmed
PATIENTS : Fifteen hospitalized
patients with proven
IFIs who were treated with oral
voriconazole for at least 2 weeks . -
pubmed
fAUC24 : MIC values higher than 25 and fCmin : MIC values higher than 1 may predict clinical response in
patients with
IFIs . -
pubmed
Designing an optimal dosage regimen based on individual PK / PD properties will improve the efficacy in
patients with
IFIs . -
pubmed
The isolates were assessed for their
cytotoxicity against five
human tumour lines (
HL-60 ,
SMMC-7721 ,
A-549 ,
MCF-7 and
SW-480 ) , and the result showed that only 2 displayed weak inhibitory activity . -
pubmed
Although
cardiac hypertrophy developed similarly in both KO and WT
mice after daily
isoproterenol (
ISO , 100 mg / kg ) treatment via intraperitoneal injection for 2 weeks , they were functionally indiscernible . -
pubmed
In the past decade , the laparoscopic approach in
trauma patients has shown better diagnostic outcomes than traditional laparotomies . -
pubmed
OBJECTIVE : To evaluate the feasibility , safety , and clinical outcomes of plug - assisted retrograde transvenous obliteration ( PARTO ) to treat
gastric variceal hemorrhage in
patients with
portal hypertension . -
pubmed
MATERIALS AND METHODS : From May 2012 to June 2014 , 19
patients ( 11
men and 8
women , median age ; 61 , with history of
gastric variceal hemorrhage ; 17 , active
bleeding ; 2 ) who underwent PARTO using a vascular plug and a gelfoam pledget were retrospectively analyzed . -
pubmed
RESULTS : Technical success ( complete occlusion of the efferent shunt and complete filling of
gastric varix [ GV ] with a gelfoam slurry ) was achieved in 18 of 19 ( 94.7 % )
patients . -
pubmed
The
embolic materials could not reach the GV in 1
patient who had endoscopic glue injection before our procedure . -
pubmed